-- dump date 20140619_000449 -- class Genbank::CDS -- table cds_note -- id note YP_004159617.1 COGs: COG0593 ATPase involved in DNA replication initiation; InterProIPR020591: IPR003593: IPR013159: IPR001957: IPR 018312: IPR013317; KEGG: bfs:BF3617 chromosomal replication initiation protein; PFAM: Chromosomal replication initiator DnaA; Chromosomal replication initiator DnaA domain; SMART: Chromosomal replication initiator DnaA domain; AAA ATPase; SPTR: Chromosomal replication initiator protein dnaA; TIGRFAM: chromosomal replication initiator protein DnaA; PFAM: domain; Bacterial dnaA protein; TIGRFAM: chromosomal replication initiator protein DnaA YP_004159618.1 COGs: COG0778 Nitroreductase; InterPro IPR000415: IPR016446; KEGG: bth:BT_2144 oxidoreductase; PFAM: nitroreductase; SPTR: uncharacterized protein; PFAM: Nitroreductase YP_004159619.1 InterPro IPR000788: IPR013344; KEGG: bfs:BF3619 ribonucleoside reductase; PFAM: ribonucleotide reductase large subunit; SPTR: Ribonucleoside-diphosphate reductase; TIGRFAM: ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; manually curated; PFAM: Ribonucleotide reductase, all-alpha domain; Ribonucleotide reductase, barrel domain; TIGRFAM: ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent YP_004159620.1 COGs: COG1640 4-alpha-glucanotransferase; InterPro IPR002044: IPR003385; KEGG: bfs:BF3620 alpha-glucanotransferase; PFAM: glycoside hydrolase 77; glycoside hydrolase starch-binding; PRIAM: 4-alpha-glucanotransferase; SPTR: uncharacterized protein; PFAM: Starch binding domain; 4-alpha-glucanotransferase; TIGRFAM: 4-alpha-glucanotransferase YP_004159621.1 COGs: COG1539 Dihydroneopterin aldolase; InterPro IPR006157: IPR006156; KEGG: bfs:BF3622 dihydroneopterin aldolase; PFAM: dihydroneopterin aldolase; SPTR: Dihydroneopterin aldolase; TIGRFAM: dihydroneopterin aldolase; PFAM: Dihydroneopterin aldolase; TIGRFAM: dihydroneopterin aldolase; FolB domain YP_004159622.1 InterPro IPR000189: IPR008258; KEGG: bvu:BVU_0605 glycoside hydrolase; PFAM: Lytic transglycosylase catalytic; SPTR: glycoside hydrolase 23; PFAM: Transglycosylase SLT domain YP_004159623.1 InterPro IPR013728; KEGG: bth:BT_1045 hypothetical protein; PFAM: domain of unknown function DUF1735; SPTR: Concanavalin A-like lectin/glucanase; PFAM: Domain of unknown function (DUF1735) YP_004159624.1 InterPro IPR001579; KEGG: bth:BT_1044 hypothetical protein; SPTR: secreted endoglycosidase, GH family 18; PFAM: glycosyl hydrolases family 18 YP_004159625.1 KEGG: bth:BT_1043 hypothetical protein; SPTR: SusD homolog YP_004159626.1 COGs: COG1629 Outer membrane receptor protein mostly Fe transport; InterPro IPR011662: IPR012910: IPR000531; KEGG: bth:BT_1042 hypothetical protein; PFAM: TonB-dependent receptor; TonB-dependent receptor plug; Secretin/TonB short domain; SPTR: SusC homolog; PFAM: TonB-dependent Receptor Plug Domain; TonB dependent receptor; Secretin and TonB N terminus short domain YP_004159627.1 COGs: COG3712 Fe2+-dicitrate sensor membrane component; InterPro IPR006860: IPR012373; KEGG: bfr:BF1325 anti-sigma factor; PFAM: FecR protein; SPTR: Fe2+-dicitrate sensor, membrane component; PFAM: FecR protein YP_004159628.1 COGs: COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog; InterProIPR000838: IPR007627: IPR013249: IPR014284: IPR 014327; KEGG: bfs:BF1308 RNA polymerase ECF-type sigma factor; PFAM: Sigma-70 region 4 type 2; sigma-70 region 2 domain protein; SPTR: RNA polymerase ECF-type sigma factor; TIGRFAM: RNA polymerase sigma-70 factor; RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; RNA polymerase sigma-70 factor, Bacteroides expansion family 1 YP_004159629.1 COGs: COG1803 methylglyoxal synthase; InterPro IPR004363: IPR018148: IPR011607; KEGG: bfs:BF3624 methylglyoxal synthase; PFAM: MGS domain protein; PRIAM: methylglyoxal synthase; SPTR: uncharacterized protein; PFAM: MGS-like domain; TIGRFAM: methylglyoxal synthase YP_004159630.1 COGs: COG1216 glycosyltransferase; InterPro IPR001173; KEGG: bfr:BF3854 glycosyltransferase; PFAM: glycosyl transferase 2; SPTR: uncharacterized protein; PFAM: glycosyl transferase 2 YP_004159631.1 COGs: COG0621 2-methylthioadenine synthetase; InterProIPR013848: IPR006638: IPR020612: IPR007197: IPR 005839: IPR006467; KEGG: bth:BT_2153 Fe-S oxidoreductase; PFAM: protein of unknown function UPF0004; radical SAM protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: uncharacterized protein; TIGRFAM: MiaB-like tRNA modifying enzyme; RNA modification enzyme, MiaB family; PFAM: Radical SAM superfamily; Uncharacterized protein family UPF0004; TIGRFAM: MiaB-like tRNA modifying enzyme; RNA modification enzyme, MiaB family YP_004159632.1 COGs: COG1022 Long-chain acyl-CoA synthetase (AMP-forming); InterPro IPR020845: IPR000873; KEGG: bfs:BF3628 long-chain-fatty-acid--CoA ligase; PFAM: AMP-dependent synthetase and ligase; SPTR: uncharacterized protein; PFAM: AMP-binding enzyme YP_004159633.1 KEGG: bfs:BF3629 hypothetical protein; SPTR: Predicted protein YP_004159634.1 COGs: COG0359 Ribosomal protein L9; InterPro IPR020594: IPR020070: IPR020069; KEGG: bfs:BF3630 50S ribosomal protein L9; PFAM: Ribosomal protein L9-like; SPTR: 50S ribosomal protein L9; TIGRFAM: ribosomal protein L9; PFAM: Ribosomal protein L9, N-terminal domain; Ribosomal protein L9, C-terminal domain; TIGRFAM: ribosomal protein L9 YP_004159635.1 COGs: COG0238 Ribosomal protein S18; InterPro IPR001648: IPR018275; KEGG: bfs:BF3631 30S ribosomal protein S18; PFAM: ribosomal protein S18; SPTR: 30S ribosomal protein S18; TIGRFAM: ribosomal protein S18; PFAM: Ribosomal protein S18; TIGRFAM: ribosomal protein S18 YP_004159636.1 COGs: COG0360 Ribosomal protein S6; InterPro IPR020814: IPR000529; KEGG: bvu:BVU_0013 30S ribosomal protein S6; PFAM: Ribosomal protein S6, bacterial-like; SPTR: 30S ribosomal protein S6; TIGRFAM: ribosomal protein S6; PFAM: Ribosomal protein S6; TIGRFAM: ribosomal protein S6 YP_004159637.1 COGs: COG1846 Transcriptional regulators; InterPro IPR000835; KEGG: bfs:BF3633 MarR family regulatory protein; PFAM: regulatory protein MarR; SMART: regulatory protein MarR; SPTR: uncharacterized protein; PFAM: MarR family YP_004159638.1 KEGG: pgn:PGN_1385 hypothetical protein; SPTR: uncharacterized protein YP_004159639.1 COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789: IPR001867; KEGG: bth:BT_2165 two-component system response regulator; PFAM: response regulator receiver; transcriptional regulator domain-containing protein; SMART: response regulator receiver; SPTR: uncharacterized protein; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal YP_004159640.1 COGs: COG0642 Signal transduction histidine kinase; InterPro IPR005467: IPR004358: IPR003661: IPR003594; KEGG: bfs:BF3635 two-component regulatory system, sensor kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: uncharacterized protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain YP_004159641.1 COGs: COG0480 Translation elongation factors (GTPase); InterProIPR000795: IPR004161: IPR005517: IPR000640: IPR 005225; KEGG: bfs:BF3636 elongation factor G; PFAM: protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; elongation factor G domain IV; elongation factor G domain-containing protein; SPTR: uncharacterized protein; TIGRFAM: small GTP-binding protein; PFAM: Elongation factor Tu domain 2; Elongation factor G C-terminus; Elongation factor Tu GTP binding domain; Elongation factor G, domain IV; TIGRFAM: translation elongation factor EF-G; small GTP-binding protein domain YP_004159642.1 COGs: COG3250 Beta-galactosidase/beta-glucuronidase; InterProIPR006101: IPR006104: IPR006102: IPR006103: IPR 004199; KEGG: pdi:BDI_0983 beta-galactosidase; PFAM: glycoside hydrolase 2; glycoside hydrolase 2 sugar binding; glycoside hydrolase 2 immunoglobulin domain protein beta-sandwich; glycoside hydrolase 42 domain 5 loop region; SPTR: uncharacterized protein; PFAM: domain; glycosyl hydrolases family 2, TIM barrel domain; glycosyl hydrolases family 2, sugar binding domain; Beta galactosidase small chain YP_004159643.1 COGs: COG0635 Coproporphyrinogen III oxidase and related Fe-S oxidoreductase; InterPro IPR006638: IPR007197: IPR010723: IPR004559; KEGG: bth:BT_2168 coproporphyrinogen III oxidase; PFAM: radical SAM protein; HemN domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: uncharacterized protein; TIGRFAM: oxygen-independent coproporphyrinogen III oxidase; PFAM: Radical SAM superfamily; HemN C-terminal region; TIGRFAM: oxygen-independent coproporphyrinogen III oxidase YP_004159644.1 COGs: COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog; InterPro IPR007627: IPR013249: IPR014284: IPR014327; KEGG: bth:BT_2169 RNA polymerase ECF-type sigma factor; PFAM: Sigma-70 region 4 type 2; sigma-70 region 2 domain protein; SPTR: RNA polymerase ECF-type sigma factor; TIGRFAM: RNA polymerase sigma-70 factor; RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; RNA polymerase sigma-70 factor, Bacteroides expansion family 1 YP_004159645.1 COGs: COG3712 Fe2+-dicitrate sensor membrane component; InterPro IPR006860: IPR012373; KEGG: bfs:BF3641 transmembrane sensor/regulatory protein; PFAM: FecR protein; SPTR: uncharacterized protein; PFAM: FecR protein YP_004159646.1 COGs: COG1629 Outer membrane receptor protein mostly Fe transport; InterPro IPR011662: IPR012910: IPR000531; KEGG: bfs:BF3642 hypothetical protein; PFAM: TonB-dependent receptor plug; Secretin/TonB short domain; TonB-dependent receptor; SPTR: uncharacterized protein; PFAM: TonB-dependent Receptor Plug Domain YP_004159647.1 KEGG: bfs:BF3643 lipoprotein; SPTR: uncharacterized protein YP_004159648.1 KEGG: bfs:BF3646 hypothetical protein; SPTR: uncharacterized protein YP_004159649.1 COGs: COG3279 Response regulator of the LytR/AlgR family; InterPro IPR001789: IPR007492; KEGG: bvu:BVU_3800 two-component system response regulator; PFAM: response regulator receiver; LytTr DNA-binding region; SMART: response regulator receiver; SPTR: uncharacterized protein; PFAM: Response regulator receiver domain; LytTr DNA-binding domain YP_004159650.1 COGs: COG3275 regulator of cell autolysis; InterPro IPR019734: IPR013026: IPR010559: IPR003594; KEGG: bvu:BVU_3801 two-component system sensor kinase; PFAM: histidine kinase internal region; ATP-binding region ATPase domain protein; SPTR: uncharacterized protein; PFAM: Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase YP_004159651.1 KEGG: bth:BT_4605 hypothetical protein; SPTR: uncharacterized protein YP_004159652.1 KEGG: edi:EDI_182940 hypothetical protein; SPTR: uncharacterized protein YP_004159653.1 COGs: COG3119 Arylsulfatase A; InterPro IPR000917; KEGG: rba:RB12325 arylsulfatase A precursor; PFAM: sulfatase; SPTR: Arylsulfatase A; PFAM: Sulfatase YP_004159654.1 InterPro IPR002625: IPR018598; KEGG: bfs:BF3653 hypothetical protein; PFAM: Domain of unknown function DUF2027; Smr protein/MutS2; SPTR: uncharacterized protein; PFAM: Domain of unknown function (DUF2027); Smr domain YP_004159655.1 COGs: COG0809 S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase); InterPro IPR003699; KEGG: bfs:BF3654 S-adenosylmethionine:tRNA ribosyltransferase-isomerase; PFAM: Queuosine biosynthesis protein; SPTR: S-adenosylmethionine:tRNA ribosyltransferase-isomerase; PFAM: Queuosine biosynthesis protein; TIGRFAM: S-adenosylmethionine:tRNA ribosyltransferase-isomerase YP_004159656.1 COGs: COG1443 Isopentenyldiphosphate isomerase; InterPro IPR020084: IPR000086; KEGG: bth:BT_3972 NTP pyrophosphohydrolase; PFAM: NUDIX hydrolase; SPTR: uncharacterized protein; PFAM: NUDIX domain YP_004159657.1 COGs: COG1109 phosphomannomutase; InterProIPR005841: IPR016066: IPR005844: IPR005845: IPR 005846: IPR005843; KEGG: bfs:BF3668 phosphoglucomutase/phosphomannomutase; PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; phosphoglucomutase/phosphomannomutase; SPTR: uncharacterized protein; PFAM: phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III; phosphoglucomutase/phosphomannomutase, C-terminal domain; phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I YP_004159658.1 KEGG: bfs:BF3669 hypothetical protein; SPTR: uncharacterized protein YP_004159659.1 COGs: COG0618 Exopolyphosphatase-related protein; InterPro IPR001667: IPR003156; KEGG: bth:BT_3948 exopolyphosphatase-like protein; PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; SPTR: uncharacterized protein; PFAM: DHH family YP_004159660.1 COGs: COG0658 membrane metal-binding protein; InterPro IPR004477; KEGG: bfr:BF3901 competence protein; PFAM: ComEC/Rec2-related protein; SPTR: uncharacterized protein; TIGRFAM: ComEC/Rec2-related protein; PFAM: Competence protein; TIGRFAM: ComEC/Rec2-related protein YP_004159661.1 KEGG: bvu:BVU_2763 hypothetical protein; SPTR: uncharacterized protein YP_004159662.1 COGs: COG3119 Arylsulfatase A; InterPro IPR000917; KEGG: bvu:BVU_2983 arylsulfatase precursor; PFAM: sulfatase; SPTR: uncharacterized protein; PFAM: Sulfatase YP_004159663.1 COGs: COG3119 Arylsulfatase A; InterPro IPR000917; KEGG: bfs:BF3094 sulfatase; PFAM: sulfatase; SPTR: N-acetylgalactosamine-6-sulfatase; PFAM: Sulfatase YP_004159664.1 InterPro IPR001760: IPR012944; KEGG: bvu:BVU_1158 hypothetical protein; PFAM: RagB/SusD domain protein; SPTR: uncharacterized protein; PFAM: SusD family YP_004159665.1 InterPro IPR012910: IPR000531; KEGG: bvu:BVU_1157 hypothetical protein; PFAM: TonB-dependent receptor plug; TonB-dependent receptor; SPTR: uncharacterized protein; PFAM: TonB dependent receptor; TonB-dependent Receptor Plug Domain YP_004159666.1 COGs: COG0036 Pentose-5-phosphate-3-epimerase; InterPro IPR000056; KEGG: bfr:BF3902 ribulose-phosphate 3-epimerase; PFAM: ribulose-phosphate 3-epimerase; PRIAM: Ribulose-phosphate 3-epimerase; SPTR: Ribulose-phosphate 3-epimerase; TIGRFAM: ribulose-phosphate 3-epimerase; PFAM: Ribulose-phosphate 3 epimerase; TIGRFAM: ribulose-phosphate 3-epimerase YP_004159667.1 COGs: COG0223 methionyl-tRNA formyltransferase; InterPro IPR005794: IPR002376: IPR005793; KEGG: bfs:BF3673 methionyl-tRNA formyltransferase; PFAM: formyl transferase domain protein; SPTR: methionyl-tRNA formyltransferase; TIGRFAM: methionyl-tRNA formyltransferase; PFAM: formyl transferase; formyl transferase, C-terminal domain; TIGRFAM: methionyl-tRNA formyltransferase YP_004159668.1 COGs: COG0038 Chloride channel protein EriC; InterPro IPR000644: IPR001807; KEGG: bfs:BF3674 transport related, membrane protein; PFAM: Cl- channel voltage-gated family protein; CBS domain containing protein; SPTR: uncharacterized protein; PFAM: CBS domain; Voltage gated chloride channel YP_004159669.1 COGs: COG0009 translation factor (SUA5); InterPro IPR006070: IPR004388; KEGG: bfs:BF3675 hypothetical protein; PFAM: SUA5/yciO/yrdC domain; SPTR: uncharacterized protein; TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; manually curated; PFAM: yrdC domain; TIGRFAM: Sua5/YciO/YrdC/YwlC family protein YP_004159670.1 COGs: COG0824 thioesterase; InterPro IPR006683; KEGG: bfs:BF3676 hypothetical protein; PFAM: thioesterase superfamily protein; SPTR: uncharacterized protein; PFAM: Thioesterase superfamily; TIGRFAM: acyl-CoA thioester hydrolase, YbgC/YbaW family YP_004159671.1 COGs: COG1609 Transcriptional regulators; InterPro IPR018060: IPR000005; KEGG: bfr:BF1760 transcriptional regulator; PFAM: helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: Transcriptional regulator; PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family YP_004159672.1 InterPro IPR011658: IPR004843; KEGG: bfr:BF1759 Icc family phosphohydrolase; PFAM: metallophosphoesterase; SMART: PA14 domain protein; SPTR: Icc family phosphohydrolase; PFAM: Calcineurin-like phosphoesterase; PA14 domain YP_004159673.1 COGs: COG3525 N-acetyl-beta-hexosaminidase; InterPro IPR001540: IPR015882: IPR015883: IPR000421; KEGG: bfr:BF1036 beta-hexosaminidase precursor; PFAM: glycoside hydrolase 20; Beta-N-acetylhexosaminidase, subunit a/b; coagulation factor 5/8 type domain protein; PRIAM: Beta-N-acetylhexosaminidase; SPTR: uncharacterized protein; PFAM: F5/8 type C domain; glycosyl hydrolase 20, catalytic domain; glycosyl hydrolase 20, domain 2 YP_004159674.1 COGs: COG3538 conserved hypothetical protein; InterPro IPR017909: IPR000425: IPR008313: IPR006311; KEGG: bfr:BF1758 hypothetical protein; PFAM: Uncharacterised conserved protein UCP028846; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF1237); TIGRFAM: Tat (twin-arginine translocation) pathway signal sequence YP_004159675.1 COGs: COG3408 glycogen debranching protein; KEGG: bfr:BF1757 hypothetical protein; SPTR: uncharacterized protein; PFAM: Mannosyl oligosaccharide glucosidase YP_004159676.1 COGs: COG1785 Alkaline phosphatase; InterPro IPR001952: IPR018299; KEGG: bfr:BF1756 alkaline phosphatase; PFAM: Alkaline phosphatase; SMART: Alkaline phosphatase; SPTR: Alkaline phosphatase; PFAM: Alkaline phosphatase YP_004159677.1 COGs: COG3568 Metal-dependent hydrolase; InterPro IPR005135; KEGG: bfr:BF1755 hypothetical protein; PFAM: Endonuclease/exonuclease/phosphatase; SPTR: uncharacterized protein; PFAM: Endonuclease/Exonuclease/phosphatase YP_004159678.1 COGs: COG3537 alpha-1 2-mannosidase; InterPro IPR011658: IPR012939: IPR005887; KEGG: bfr:BF1754 alpha-1,2-mannosidase; PFAM: glycosyl hydrolase 92; SMART: PA14 domain protein; SPTR: uncharacterized protein; TIGRFAM: alpha-1,2-mannosidase; PFAM: glycosyl hydrolase 92; PA14 domain; TIGRFAM: alpha-1,2-mannosidase YP_004159679.1 InterPro IPR012944; KEGG: pdi:BDI_3182 hypothetical protein; PFAM: RagB/SusD domain protein; SPTR: uncharacterized protein; PFAM: SusD family YP_004159680.1 InterPro IPR012910: IPR000531; KEGG: bfr:BF1752 hypothetical protein; PFAM: TonB-dependent receptor; TonB-dependent receptor plug; SPTR: uncharacterized protein; PFAM: TonB-dependent Receptor Plug Domain; TonB dependent receptor YP_004159681.1 COGs: COG1940 Transcriptional regulator/sugar kinase; InterPro IPR000600; KEGG: bfr:BF1751 transcriptional regulator; PFAM: ROK family protein; SPTR: ROK family transcriptional repressor; PFAM: ROK family YP_004159682.1 InterPro IPR000909; KEGG: bfr:BF1750 1-phosphatidylinositol phosphodiesterase precursor; SMART: phosphatidylinositol-specific phospholipase C X region; SPTR: 1-phosphatidylinositol phosphodiesterase; PFAM: phosphatidylinositol-specific phospholipase C, X domain YP_004159683.1 InterPro IPR018271: IPR007421; KEGG: pru:PRU_1139 hypothetical protein; PFAM: AAA-4 family protein; SPTR: uncharacterized protein; PFAM: Divergent AAA domain YP_004159684.1 KEGG: cat:CA2559_00400 hypothetical protein; SPTR: uncharacterized protein YP_004159685.1 COGs: COG3022 conserved hypothetical protein; InterPro IPR005583; KEGG: bvu:BVU_0413 hypothetical protein; PFAM: protein of unknown function DUF328; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF328) YP_004159686.1 COGs: COG0608 Single-stranded DNA-specific exonuclease; InterPro IPR001667: IPR003156: IPR004610; KEGG: bth:BT_3939 single-stranded-DNA-specific exonuclease RecJ; PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; SPTR: uncharacterized protein; TIGRFAM: single-stranded-DNA-specific exonuclease RecJ; PFAM: DHH family; DHHA1 domain; TIGRFAM: single-stranded-DNA-specific exonuclease RecJ YP_004159687.1 COGs: COG0514 Superfamily II DNA helicase; InterProIPR014021: IPR001650: IPR014001: IPR011545: IPR 018329; KEGG: bth:BT_3938 ATP-dependent DNA helicase RecQ; PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; SPTR: uncharacterized protein; TIGRFAM: ATP-dependent DNA helicase, RecQ family; PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase; TIGRFAM: ATP-dependent DNA helicase, RecQ family YP_004159688.1 InterPro IPR019734: IPR013026: IPR001440; KEGG: bfs:BF3707 hypothetical protein; PFAM: hypothetical protein; SPTR: uncharacterized protein; PFAM: Tetratricopeptide repeat YP_004159689.1 COGs: COG0077 Prephenate dehydratase; InterPro IPR001086; KEGG: bth:BT_3936 prephenate dehydratase; PFAM: prephenate dehydratase; PRIAM: Prephenate dehydratase; SPTR: uncharacterized protein; PFAM: Prephenate dehydratase YP_004159690.1 COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004838: IPR004839; KEGG: bfs:BF3716 aminotransferase; PFAM: aminotransferase class I and II; SPTR: uncharacterized protein; PFAM: Aminotransferase class I and II YP_004159691.1 COGs: COG2876 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase; InterPro IPR002701: IPR006218: IPR020822; KEGG: bfs:BF3717 chorismate mutase; PFAM: DAHP synthetase I/KDSA; Chorismate mutase, type II; PRIAM: 3-deoxy-7-phosphoheptulonate synthase; SPTR: uncharacterized protein; PFAM: Chorismate mutase type II; DAHP synthetase I family; TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase YP_004159692.1 COGs: COG0287 Prephenate dehydrogenase; InterPro IPR003099; KEGG: bth:BT_3933 chorismate mutase/prephenate dehydratase (TyrA); PFAM: Prephenate dehydrogenase; SPTR: uncharacterized protein; PFAM: Prephenate dehydrogenase YP_004159693.1 COGs: COG0358 DNA primase; InterProIPR002694: IPR006154: IPR013264: IPR006171: IPR 006295; KEGG: bth:BT_3932 DNA primase; PFAM: DNA primase catalytic core domain; TOPRIM domain-containing protein; SMART: Toprim sub domain-containing protein; SPTR: uncharacterized protein; TIGRFAM: DNA primase; PFAM: Toprim domain; DNA primase catalytic core, N-terminal domain; CHC2 zinc finger; DnaB-helicase binding domain of primase; TIGRFAM: DNA primase, catalytic core YP_004159694.1 COGs: COG0302 GTP cyclohydrolase I; InterPro IPR001474: IPR018234: IPR020602; KEGG: bth:BT_3931 GTP cyclohydrolase I; PFAM: GTP cyclohydrolase I/Nitrile oxidoreductase; PRIAM: GTP cyclohydrolase I; SPTR: GTP cyclohydrolase 1; TIGRFAM: GTP cyclohydrolase I; PFAM: GTP cyclohydrolase I; TIGRFAM: GTP cyclohydrolase I YP_004159695.1 InterPro IPR018130: IPR007730; KEGG: bfs:BF3728 hypothetical protein; PFAM: Sporulation domain-containing protein; SPTR: uncharacterized protein; PFAM: Sporulation related domain YP_004159696.1 COGs: COG0149 Triosephosphate isomerase; InterPro IPR000652: IPR020861; KEGG: bfs:BF3729 triosephosphate isomerase; PFAM: triosephosphate isomerase; PRIAM: Triose-phosphate isomerase; SPTR: Triosephosphate isomerase; TIGRFAM: triosephosphate isomerase; PFAM: Triosephosphate isomerase; TIGRFAM: triosephosphate isomerase YP_004159697.1 KEGG: bfr:BF3957 hypothetical protein; SPTR: uncharacterized protein; PFAM: DoxX YP_004159698.1 InterPro IPR011630; KEGG: bth:BT_3927 hypothetical protein; PFAM: protein of unknown function DUF1599; SPTR: uncharacterized protein; PFAM: Domain of Unknown Function (DUF1599) YP_004159699.1 COGs: COG0739 Membrane protein related to metalloendopeptidase; InterPro IPR002482: IPR016047: IPR018392; KEGG: bfs:BF3732 exported peptidase; PFAM: peptidase M23; peptidoglycan-binding lysin domain; SMART: peptidoglycan-binding LysM; SPTR: uncharacterized protein; PFAM: peptidase M23; LysM domain YP_004159700.1 COGs: COG1200 RecG-like helicase; InterProIPR014021: IPR001650: IPR014001: IPR019793: IPR 004365: IPR011545: IPR004609; KEGG: bfr:BF3961 ATP-dependent DNA helicase RecG; PFAM: DEAD/DEAH box helicase domain protein; nucleic acid binding OB-fold tRNA/helicase-type; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; SPTR: ATP-dependent DNA helicase RecG; TIGRFAM: ATP-dependent DNA helicase RecG; PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase; TIGRFAM: ATP-dependent DNA helicase RecG YP_004159701.1 COGs: COG1211 4-diphosphocytidyl-2-methyl-D-erithritol synthase; InterPro IPR001228; KEGG: bfs:BF3735 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; PFAM: 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; SPTR: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; TIGRFAM: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; PFAM: Uncharacterized protein family UPF0007; TIGRFAM: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase YP_004159702.1 COGs: COG0693 intracellular protease/amidase; InterPro IPR002818: IPR006287; KEGG: bth:BT_3922 ThiJ family intracellular protease/amidase; PFAM: ThiJ/PfpI domain-containing protein; SPTR: uncharacterized protein; TIGRFAM: DJ-1 family protein; PFAM: DJ-1/PfpI family; TIGRFAM: DJ-1 family protein YP_004159703.1 InterPro IPR006260; KEGG: bfs:BF3737 TonB exported protein; SPTR: uncharacterized protein; TIGRFAM: TonB family protein; TIGRFAM: TonB family C-terminal domain YP_004159704.1 COGs: COG0848 Biopolymer transport protein; InterPro IPR003400; KEGG: bfs:BF3738 tansport related protein; PFAM: Biopolymer transport protein ExbD/TolR; SPTR: uncharacterized protein; PFAM: Biopolymer transport protein ExbD/TolR YP_004159705.1 COGs: COG0811 Biopolymer transport protein; InterPro IPR002898; KEGG: bfs:BF3739 transport related membrane protein; PFAM: MotA/TolQ/ExbB proton channel; SPTR: uncharacterized protein; PFAM: MotA/TolQ/ExbB proton channel family; TC 2.C.1.1.1 YP_004159706.1 COGs: COG0854 Pyridoxal phosphate biosynthesis protein; InterPro IPR004569; KEGG: bfs:BF3740 pyridoxine 5'-phosphate synthase; PFAM: Pyridoxal phosphate biosynthetic protein PdxJ; PRIAM: Pyridoxine 5'-phosphate synthase; SPTR: Pyridoxine 5'-phosphate synthase; TIGRFAM: pyridoxal phosphate biosynthetic protein PdxJ; PFAM: Pyridoxal phosphate biosynthesis protein PdxJ; TIGRFAM: pyridoxine 5'-phosphate synthase YP_004159707.1 COGs: COG0061 sugar kinase; InterPro IPR002504; KEGG: bfs:BF3741 inorganic polyphosphate/ATP-NAD kinase; PFAM: ATP-NAD/AcoX kinase; SPTR: uncharacterized protein; PFAM: ATP-NAD kinase YP_004159708.1 COGs: COG3525 N-acetyl-beta-hexosaminidase; InterPro IPR001540: IPR015883; KEGG: bfr:BF2136 beta-hexosaminidase precursor; PFAM: glycoside hydrolase 20; PRIAM: Beta-N-acetylhexosaminidase; SPTR: uncharacterized protein; PFAM: glycosyl hydrolase 20, catalytic domain; glycosyl hydrolase 20, domain 2 YP_004159709.1 COGs: COG3250 Beta-galactosidase/beta-glucuronidase; InterPro IPR006101: IPR020904: IPR006104: IPR006103; KEGG: bvu:BVU_3844 beta-glycosidase; PFAM: glycoside hydrolase 2 sugar binding; glycoside hydrolase 2; PRIAM: Beta-galactosidase; SPTR: glycoside hydrolase 2; manually curated; PFAM: domain; glycosyl hydrolases family 2, TIM barrel domain; glycosyl hydrolases family 2, sugar binding domain YP_004159710.1 InterPro IPR010905; KEGG: bfs:BF0331 exported hydrolase; PFAM: glycosyl hydrolase 88; SPTR: uncharacterized protein; PFAM: glycosyl Hydrolase 88 YP_004159711.1 InterPro IPR012480; KEGG: bfr:BF0384 hypothetical protein; PFAM: Heparinase II/III family protein; SPTR: uncharacterized protein; PFAM: Heparinase II/III-like protein YP_004159712.1 InterPro IPR012944; KEGG: phe:Phep_3171 RagB/SusD domain protein; PFAM: RagB/SusD domain protein; SPTR: uncharacterized protein; PFAM: SusD family YP_004159713.1 COGs: COG4771 Outer membrane receptor for ferrienterochelin and colicins; InterPro IPR012910: IPR000531; KEGG: phe:Phep_3172 TonB-dependent receptor plug; PFAM: TonB-dependent receptor plug; TonB-dependent receptor; SPTR: uncharacterized protein; PFAM: TonB-dependent Receptor Plug Domain; TonB dependent receptor YP_004159714.1 COGs: COG0642 Signal transduction histidine kinase; InterProIPR018060: IPR005467: IPR001789: IPR004358: IPR 003661: IPR003594: IPR018062: IPR011110: IPR001180: IPR011123:I PR000005; KEGG: bth:BT_3334 two-component system sensor histidine kinase/response regulator, hybrid ('one-component system'); PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; two component regulator three Y domain-containing protein; Citron-like; two component regulator propeller; response regulator receiver; helix-turn-helix- domain containing protein AraC type; SMART: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; Helix-turn-helix, AraC domain; SPTR: uncharacterized protein; PFAM: Y_Y_Y domain; Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; two component regulator propeller; His Kinase A (phosphoacceptor) domain; Bacterial regulatory helix-turn-helix proteins, AraC family YP_004159715.1 COGs: COG3119 Arylsulfatase A; InterPro IPR000917; KEGG: rba:RB4784 arylsulfatase A precursor; PFAM: sulfatase; SPTR: Arylsulfatase A; PFAM: Sulfatase YP_004159716.1 COGs: COG3119 Arylsulfatase A; InterPro IPR000917; KEGG: bvu:BVU_1159 sulfatase; PFAM: sulfatase; SPTR: Aryl-sulphate sulphohydrolase; PFAM: Sulfatase YP_004159717.1 InterPro IPR012944; KEGG: bth:BT_0755 hypothetical protein; PFAM: RagB/SusD domain protein; SPTR: uncharacterized protein; PFAM: SusD family YP_004159718.1 InterPro IPR011662: IPR012910: IPR000531; KEGG: bth:BT_4357 hypothetical protein; PFAM: TonB-dependent receptor plug; Secretin/TonB short domain; TonB-dependent receptor; SPTR: SusC homolog; PFAM: TonB dependent receptor; TonB-dependent Receptor Plug Domain; Secretin and TonB N terminus short domain YP_004159719.1 COGs: COG3712 Fe2+-dicitrate sensor membrane component; InterPro IPR006860: IPR012373; KEGG: pdi:BDI_2335 anti-sigma factor; PFAM: FecR protein; SPTR: uncharacterized protein; PFAM: FecR protein YP_004159720.1 COGs: COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog; InterPro IPR007627: IPR013249: IPR014284: IPR014327; KEGG: pdi:BDI_2336 RNA polymerase ECF-type sigma factor; PFAM: Sigma-70 region 4 type 2; sigma-70 region 2 domain protein; SPTR: uncharacterized protein; TIGRFAM: RNA polymerase sigma-70 factor; RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; RNA polymerase sigma-70 factor, Bacteroides expansion family 1 YP_004159721.1 COGs: COG0793 Periplasmic protease; InterPro IPR011659: IPR005151: IPR012393; KEGG: bfr:BF3977 tricorn-like protease; PFAM: peptidase S41; hypothetical protein; SPTR: uncharacterized protein; PFAM: WD40-like Beta Propeller Repeat; peptidase S41 YP_004159722.1 COGs: COG0039 Malate/lactate dehydrogenase; InterPro IPR001557: IPR011275: IPR001236; KEGG: bfs:BF3753 malate dehydrogenase; PFAM: Lactate/malate dehydrogenase; SPTR: Malate dehydrogenase; TIGRFAM: malate dehydrogenase, NAD-dependent; PFAM: lactate/malate dehydrogenase, alpha/beta C-terminal domain; lactate/malate dehydrogenase, NAD binding domain; TIGRFAM: malate dehydrogenase, NAD-dependent YP_004159723.1 KEGG: bfs:BF3754 hypothetical protein; SPTR: uncharacterized protein YP_004159724.1 COGs: COG1538 Outer membrane protein; InterPro IPR003423; KEGG: bfs:BF3759 outer membrane protein; PFAM: outer membrane efflux protein; SPTR: uncharacterized protein; PFAM: Outer membrane efflux protein YP_004159725.1 COGs: COG1566 Multidrug resistance efflux pump; InterPro IPR006143; KEGG: bfs:BF3760 hypothetical protein; PFAM: hemolysin D; SPTR: uncharacterized protein; PFAM: HlyD family secretion protein YP_004159726.1 InterPro IPR000209: IPR013525; KEGG: bfs:BF3761 transport-related membrane protein; PFAM: ABC-2 type transporter; SPTR: uncharacterized protein; PFAM: ABC-2 type transporter YP_004159727.1 COGs: COG0842 ABC-type multidrug transport system permease component; InterPro IPR013525; KEGG: bfr:BF3987 hypothetical protein; PFAM: ABC-2 type transporter; SPTR: uncharacterized protein; PFAM: ABC-2 type transporter YP_004159728.1 KEGG: bfs:BF3797 hypothetical protein; SPTR: uncharacterized protein YP_004159729.1 KEGG: bfs:BF3798 hypothetical protein; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF1812) YP_004159730.1 KEGG: bfr:BF4025 hypothetical protein; SPTR: uncharacterized protein YP_004159731.1 KEGG: bfs:BF3800 outer membrane protein; SPTR: outer membrane protein YP_004159732.1 COGs: COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)protein; InterProIPR019734: IPR013026: IPR006665: IPR006664: IPR 011659; KEGG: bfs:BF3801 hypothetical protein; PFAM: OmpA/MotB domain protein; hypothetical protein; SMART: Tetratricopeptide repeat; SPTR: exported protein; PFAM: WD40-like Beta Propeller Repeat; OmpA family YP_004159733.1 KEGG: bfs:BF3802 hypothetical protein; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF3575) YP_004159734.1 KEGG: bfr:BF4030 hypothetical protein; SPTR: uncharacterized protein YP_004159735.1 KEGG: bfr:BF4031 hypothetical protein; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF1812) YP_004159736.1 InterPro IPR002104; KEGG: bfs:BF3806 tyrosine site-specific recombinase; PFAM: integrase; SPTR: Tyrosine type site-specific recombinase; PFAM: Phage integrase YP_004159737.1 COGs: COG1664 Integral membrane protein CcmA involved in cell shape determination; InterPro IPR007607; KEGG: bfs:BF3807 hypothetical protein; PFAM: protein of unknown function DUF583; SPTR: uncharacterized protein; PFAM: Protein of unknown function, DUF583 YP_004159738.1 KEGG: tgu:100223757 similar to chondroitin sulfate synthase 3; SPTR: membrane protein YP_004159739.1 COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683; KEGG: bvu:BVU_2041 oxidoreductase; PFAM: oxidoreductase domain protein; PRIAM: alpha-N-acetylgalactosaminidase; SPTR: uncharacterized protein; PFAM: Oxidoreductase, NAD-binding Rossmann fold YP_004159740.1 COGs: COG1501 alpha-glucosidase 31 of glycosyl hydrolase; InterPro IPR000421: IPR003961: IPR018247: IPR000322; KEGG: bfr:BF1144 alpha-xylosidase; PFAM: glycoside hydrolase 31; Fibronectin type III domain protein; coagulation factor 5/8 type domain protein; SPTR: uncharacterized protein; PFAM: F5/8 type C domain; glycosyl hydrolases family 31 YP_004159741.1 InterPro IPR012944; KEGG: bfr:BF0947 hypothetical protein; PFAM: RagB/SusD domain protein; SPTR: lipoprotein; PFAM: SusD family YP_004159742.1 COGs: COG1629 Outer membrane receptor protein mostly Fe transport; InterPro IPR012910: IPR000531; KEGG: bfs:BF0868 TonB-linked outer membrane protein; PFAM: TonB-dependent receptor; TonB-dependent receptor plug; SPTR: uncharacterized protein; PFAM: TonB dependent receptor; TonB-dependent Receptor Plug Domain; Secretin and TonB N terminus short domain YP_004159743.1 COGs: COG3712 Fe2+-dicitrate sensor membrane component; InterPro IPR006860; KEGG: bfs:BF0231 regulatory protein; PFAM: FecR protein; SPTR: uncharacterized protein; PFAM: FecR protein YP_004159744.1 COGs: COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog; InterPro IPR007627: IPR013249: IPR014284: IPR014327; KEGG: bfs:BF0232 ECF-type sigma factor; PFAM: Sigma-70 region 4 type 2; sigma-70 region 2 domain protein; SPTR: RNA polymerase ECF-type sigma factor; TIGRFAM: RNA polymerase sigma-70 factor; RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; RNA polymerase sigma-70 factor, Bacteroides expansion family 1 YP_004159745.1 COGs: COG3682 transcriptional regulator protein; InterPro IPR005650; KEGG: bfs:BF3766 hypothetical protein; PFAM: Penicillinase repressor; SPTR: uncharacterized protein; PFAM: Penicillinase repressor YP_004159746.1 COGs: COG0810 Periplasmic protein TonB links inner and outer membranes; InterPro IPR008756: IPR006260; KEGG: bth:BT_3898 TonB; PFAM: peptidase M56 BlaR1; TonB domain; SPTR: uncharacterized protein; TIGRFAM: TonB family protein; PFAM: BlaR1 peptidase M56; Gram-negative bacterial tonB protein; TIGRFAM: TonB family C-terminal domain; TC 2.C.1.1.1 YP_004159747.1 COGs: COG0489 ATPase involved in chromosome partitioning; InterPro IPR019591; KEGG: bth:BT_3895 Mrp/Nbp35 family ATP-binding protein; PFAM: ATPase-like, ParA/MinD; SPTR: uncharacterized protein; PFAM: ParA/MinD ATPase like; Anion-transporting ATPase YP_004159748.1 COGs: COG0220 S-adenosylmethionine-dependent methyltransferase; InterPro IPR003358; KEGG: bvu:BVU_0267 tRNA (guanine-N(7)-)-methyltransferase; PFAM: methyltransferase; PRIAM: tRNA (guanine-N(7)-)-methyltransferase; SPTR: uncharacterized protein; PFAM: methyltransferase; TIGRFAM: tRNA (guanine-N(7)-)-methyltransferase YP_004159749.1 COGs: COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase; InterPro IPR001544: IPR005786; KEGG: bfs:BF3772 branched-chain amino acid aminotransferase; PFAM: aminotransferase class IV; SPTR: uncharacterized protein; TIGRFAM: branched-chain amino acid aminotransferase; PFAM: Aminotransferase class IV; TIGRFAM: branched-chain amino acid aminotransferase, group II YP_004159750.1 InterPro IPR003761; KEGG: bth:BT_3891 hypothetical protein; PFAM: Exonuclease VII small subunit; SPTR: uncharacterized protein; PFAM: Exonuclease VII small subunit YP_004159751.1 COGs: COG1570 Exonuclease VII large subunit; InterPro IPR020579; KEGG: bfs:BF3774 exodeoxyribonuclease VII large subunit; PFAM: Exonuclease VII, large subunit-like; SPTR: Exodeoxyribonuclease 7 large subunit; PFAM: Exonuclease VII, large subunit; TIGRFAM: exodeoxyribonuclease VII, large subunit YP_004159752.1 COGs: COG1404 Subtilisin-like serine protease; InterPro IPR000209: IPR017317; KEGG: bfs:BF3775 subtilase serine protease; PFAM: peptidase S8 and S53 subtilisin kexin sedolisin; SPTR: uncharacterized protein; PFAM: Subtilase YP_004159753.1 COGs: COG0482 tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase contains the PP-loop ATPase domain; InterPro IPR004506; KEGG: bfs:BF3776 tRNA-specific 2-thiouridylase MnmA; SPTR: uncharacterized protein; TIGRFAM: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; PFAM: tRNA methyl transferase; TIGRFAM: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase YP_004159754.1 InterPro IPR010870; KEGG: bth:BT_3553 hypothetical protein; PFAM: phosphate-selective porin O and P; SPTR: uncharacterized protein; PFAM: phosphate-selective porin O and P YP_004159755.1 InterPro IPR004843: IPR011230; KEGG: bth:BT_3885 Icc family phosphohydrolase; PFAM: metallophosphoesterase; SPTR: uncharacterized protein; PFAM: Calcineurin-like phosphoesterase YP_004159756.1 COGs: COG0245 2C-methyl-D-erythritol 2 4-cyclodiphosphate synthase; InterPro IPR003526: IPR020555; KEGG: bfs:BF3780 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; PFAM: MECDP-synthase; SPTR: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; TIGRFAM: 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; PFAM: YgbB family; TIGRFAM: 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase YP_004159757.1 COGs: COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1 7-dioic acid hydratase (catechol pathway); InterPro IPR002529; KEGG: bfs:BF3781 hydrolase; PFAM: fumarylacetoacetate (FAA) hydrolase; SPTR: uncharacterized protein; PFAM: Fumarylacetoacetate (FAA) hydrolase YP_004159758.1 COGs: COG2344 AT-rich DNA-binding protein; InterPro IPR009718: IPR003781; KEGG: bfs:BF3782 redox-sensing transcriptional repressor REX; PFAM: CoA-binding domain protein; Rex DNA-binding domain protein; SPTR: uncharacterized protein; PFAM: CoA binding domain; DNA-binding protein N-terminus YP_004159759.1 COGs: COG0023 Translation initiation factor 1 (eIF-1/SUI1) and related protein; InterPro IPR001950: IPR017228; KEGG: bfr:BF4009 translation initiation factor SUI1; PFAM: translation initiation factor SUI1; SPTR: uncharacterized protein; PFAM: Translation initiation factor SUI1; TIGRFAM: translation initation factor SUI1, , prokaryotic YP_004159760.1 COGs: COG0264 Translation elongation factor Ts; InterPro IPR001816: IPR018101: IPR000449: IPR014039; KEGG: bth:BT_3878 elongation factor Ts; PFAM: Translation elongation factor EFTs/EF1B dimerisation; ubiquitin-associated- domain-containing protein; SPTR: Elongation factor Ts; TIGRFAM: translation elongation factor Ts; PFAM: Elongation factor TS; UBA/TS-N domain; TIGRFAM: translation elongation factor Ts YP_004159761.1 COGs: COG0052 Ribosomal protein S2; InterPro IPR001865: IPR018130: IPR005706; KEGG: bth:BT_3877 30S ribosomal protein S2; PFAM: ribosomal protein S2; SPTR: uncharacterized protein; TIGRFAM: ribosomal protein S2; PFAM: Ribosomal protein S2; TIGRFAM: ribosomal protein S2, bacterial type YP_004159762.1 COGs: COG0103 Ribosomal protein S9; InterPro IPR020574: IPR000754; KEGG: bfs:BF3786 30S ribosomal protein S9; PFAM: ribosomal protein S9; SPTR: 30S ribosomal protein S9; PFAM: Ribosomal protein S9/S16 YP_004159763.1 COGs: COG0102 Ribosomal protein L13; InterPro IPR005822: IPR005823; KEGG: bfs:BF3787 50S ribosomal protein L13; PFAM: ribosomal protein L13; SPTR: 50S ribosomal protein L13; TIGRFAM: ribosomal protein L13; PFAM: Ribosomal protein L13; TIGRFAM: ribosomal protein L13, bacterial type YP_004159764.1 KEGG: bvu:BVU_1631 hypothetical protein; SPTR: uncharacterized protein YP_004159765.1 KEGG: bth:BT_3874 hypothetical protein; SPTR: uncharacterized protein YP_004159766.1 COGs: COG0017 Aspartyl/asparaginyl-tRNA synthetase; InterProIPR006195: IPR002312: IPR004365: IPR004364: IPR 004522; KEGG: bvu:BVU_1628 asparaginyl-tRNA synthetase; PFAM: tRNA synthetase class II (D K and N); nucleic acid binding OB-fold tRNA/helicase-type; PRIAM: Asparagine--tRNA ligase; SPTR: Asparaginyl-tRNA synthetase; TIGRFAM: asparaginyl-tRNA synthetase; PFAM: tRNA synthetases class II (D, K and N); OB-fold nucleic acid binding domain; TIGRFAM: asparaginyl-tRNA synthetase YP_004159767.1 COGs: COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthase; InterPro IPR002942: IPR018496: IPR006145: IPR000748; KEGG: bth:BT_3872 ribosomal large subunit pseudouridine synthase B; PFAM: RNA-binding S4 domain protein; pseudouridine synthase; SMART: RNA-binding S4 domain protein; SPTR: Pseudouridine synthase; PFAM: RNA pseudouridylate synthase; S4 domain; TIGRFAM: pseudouridine synthase YP_004159768.1 COGs: COG0015 Adenylosuccinate lyase; InterPro IPR000362: IPR020557: IPR013539: IPR004769; KEGG: bth:BT_3871 adenylosuccinate lyase; PFAM: Adenylosuccinate lyase domain-containing protein; fumarate lyase; SPTR: uncharacterized protein; TIGRFAM: adenylosuccinate lyase; PFAM: Lyase; Adenylosuccinate lyase C-terminal; TIGRFAM: adenylosuccinate lyase YP_004159769.1 COGs: COG0110 Acetyltransferase (isoleucine patch superfamily); InterPro IPR001451; KEGG: bfs:BF3794 maltose O-acetyltransferase; SPTR: uncharacterized protein YP_004159770.1 InterPro IPR002547; KEGG: bcz:pE33L466_0260 protein secretion chaperonin; PFAM: tRNA-binding protein; SPTR: uncharacterized protein; PFAM: tRNA binding domain; TIGRFAM: export-related chaperone CsaA YP_004159771.1 COGs: COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); InterProIPR011761: IPR005483: IPR005479: IPR005481: IPR 005480: IPR011607: IPR006275; KEGG: bfs:BF3808 carbamoyl-phosphate synthase large chain 2; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; Carbamoyl-phosphate synthetase large chain oligomerisation; MGS domain protein; SPTR: uncharacterized protein; TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain, ATP binding domain; MGS-like domain; Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Carbamoyl-phosphate synthase L chain, N-terminal domain; TIGRFAM: carbamoyl-phosphate synthase, large subunit YP_004159772.1 SPTR: Carbamoyl-phosphate synthase large subunit YP_004159773.1 COGs: COG3568 Metal-dependent hydrolase; InterPro IPR005135; KEGG: dfe:Dfer_2405 endonuclease/exonuclease/phosphatase; PFAM: Endonuclease/exonuclease/phosphatase; SPTR: uncharacterized protein; PFAM: Endonuclease/Exonuclease/phosphatase YP_004159774.1 InterPro IPR012944; KEGG: pdi:BDI_3111 hypothetical protein; PFAM: RagB/SusD domain protein; SPTR: lipoprotein; PFAM: SusD family YP_004159775.1 InterPro IPR012910: IPR000531; KEGG: pdi:BDI_3110 hypothetical protein; PFAM: TonB-dependent receptor; TonB-dependent receptor plug; SPTR: outer membrane protein probably involved in nutrient binding; PFAM: TonB-dependent Receptor Plug Domain; TonB dependent receptor YP_004159776.1 KEGG: lbc:LACBIDRAFT_305747 hypothetical protein; SPTR: uncharacterized protein YP_004159777.1 KEGG: pdi:BDI_3895 hypothetical protein; SPTR: uncharacterized protein YP_004159778.1 KEGG: bfs:BF1725 hypothetical protein; SPTR: uncharacterized protein; manually curated YP_004159779.1 KEGG: bfs:BF1726 hypothetical protein; SPTR: uncharacterized protein YP_004159780.1 COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR000005: IPR018060; KEGG: bfs:BF1727 AraC family transcriptional regulator; PFAM: helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: AraC family transcriptional regulator; PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family YP_004159781.1 InterPro IPR018534; KEGG: bfs:BF1728 hypothetical protein; PFAM: Tetracycline regulation of excision, RteC; SPTR: uncharacterized protein; PFAM: RteC protein YP_004159782.1 InterPro IPR010093; KEGG: bfs:BF1729 hypothetical protein; SPTR: uncharacterized protein; TIGRFAM: DNA binding domain protein, excisionase; manually curated; TIGRFAM: DNA binding domain, excisionase YP_004159783.1 KEGG: bfs:BF1730 hypothetical protein; SPTR: uncharacterized protein YP_004159784.1 KEGG: bfs:BF1731 hypothetical protein; SPTR: uncharacterized protein YP_004159785.1 InterPro IPR002734; KEGG: bfs:BF1732 hypothetical protein; PFAM: bifunctional deaminase-reductase domain protein; SPTR: uncharacterized protein; PFAM: RibD C-terminal domain YP_004159786.1 KEGG: bfs:BF1733 hypothetical protein; SPTR: uncharacterized protein YP_004159787.1 KEGG: bfs:BF1734 hypothetical protein; SPTR: uncharacterized protein YP_004159788.1 KEGG: bfs:BF1735 hypothetical protein; SPTR: uncharacterized protein YP_004159789.1 COGs: COG0550 Topoisomerase IA; InterProIPR005738: IPR003601: IPR000380: IPR003602: IPR 006171: IPR006154: IPR013497; KEGG: bfs:BF1736 DNA topoisomerase I; PFAM: DNA topoisomerase type IA central domain protein; TOPRIM domain-containing protein; PRIAM: DNA topoisomerase; SMART: DNA topoisomerase I DNA-binding; DNA topoisomerase I ATP-binding; Toprim sub domain-containing protein; SPTR: DNA topoisomerase I; TIGRFAM: DNA topoisomerase III; PFAM: Toprim domain; DNA topoisomerase; TIGRFAM: DNA topoisomerase III, bacteria and conjugative plasmid YP_004159790.1 KEGG: bfs:BF1737 hypothetical protein; SPTR: uncharacterized protein YP_004159791.1 COGs: COG4974 Site-specific recombinase XerD; InterPro IPR002104; KEGG: bfs:BF1738 tyrosine recombinase; PFAM: integrase; SPTR: Tyrosine recombinase XerC; PFAM: Phage integrase, N-terminal SAM-like domain; Phage integrase; TIGRFAM: integron integrase YP_004159792.1 KEGG: bfs:BF1788 hypothetical protein; SPTR: uncharacterized protein YP_004159793.1 KEGG: bfs:BF1789 hypothetical protein; SPTR: uncharacterized protein YP_004159795.1 InterPro IPR017896: IPR017900; KEGG: bfs:BF1790 ferredoxin; SPTR: ferredoxin YP_004159796.1 COGs: COG1733 transcriptional regulator protein; InterPro IPR002577; KEGG: bfs:BF1791 transcriptional regulator; PFAM: helix-turn-helix HxlR type; SPTR: transcriptional regulator; PFAM: HxlR-like helix-turn-helix YP_004159797.1 KEGG: bfs:BF1792 hypothetical protein; SPTR: uncharacterized protein YP_004159798.1 KEGG: bfs:BF1793 hypothetical protein; SPTR: uncharacterized protein YP_004159799.1 KEGG: bfs:BF1794 hypothetical protein; SPTR: uncharacterized protein YP_004159800.1 COGs: COG4974 Site-specific recombinase XerD; InterPro IPR016059: IPR002104; KEGG: bfs:BF1795 bacteriophage integrase; PFAM: integrase; SPTR: bacteriophage integrase; PFAM: Phage integrase YP_004159801.1 InterPro IPR005902; KEGG: bth:BT_4601 hypothetical protein; SPTR: uncharacterized protein; TIGRFAM: DNA-binding protein; TIGRFAM: DNA-binding protein, histone-like YP_004159802.1 COGs: COG0180 Tryptophanyl-tRNA synthetase; InterPro IPR002306: IPR001412: IPR002305; KEGG: bfs:BF3809 tryptophanyl-tRNA synthetase II; PFAM: aminoacyl-tRNA synthetase class Ib; SPTR: Tryptophanyl-tRNA synthetase; TIGRFAM: tryptophanyl-tRNA synthetase; PFAM: tRNA synthetases class I (W and Y); TIGRFAM: tryptophanyl-tRNA synthetase YP_004159803.1 COGs: COG0323 DNA mismatch repair enzyme (predicted ATPase); InterProIPR020667: IPR014762: IPR003594: IPR013507: IPR 014790: IPR014763; KEGG: bth:BT_3851 DNA mismatch repair protein MutL; PFAM: MutL dimerisation; DNA mismatch repair protein domain protein; ATP-binding region ATPase domain protein; SPTR: DNA mismatch repair protein mutL; TIGRFAM: DNA mismatch repair protein MutL; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; MutL C terminal dimerisation domain; DNA mismatch repair protein, C-terminal domain; TIGRFAM: DNA mismatch repair protein MutL YP_004159804.1 KEGG: bfs:BF3886 hypothetical protein; SPTR: uncharacterized protein YP_004159805.1 KEGG: bth:BT_3849 hypothetical protein; SPTR: uncharacterized protein YP_004159806.1 InterPro IPR000297; KEGG: bth:BT_3848 peptidyl-prolyl cis-trans isomerase; PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; SPTR: uncharacterized protein; PFAM: PPIC-type PPIASE domain YP_004159807.1 KEGG: bfs:BF3889 hypothetical protein; SPTR: uncharacterized protein YP_004159808.1 InterPro IPR000297; KEGG: bfs:BF3890 exported isomerase; PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; SPTR: uncharacterized protein; PFAM: PPIC-type PPIASE domain YP_004159809.1 COGs: COG0516 IMP dehydrogenase/GMP reductase; InterProIPR000644: IPR015875: IPR001093: IPR005990: IPR 018529; KEGG: bvu:BVU_0428 inosine-5'-monophosphate dehydrogenase; PFAM: IMP dehydrogenase/GMP reductase; CBS domain containing protein; PRIAM: IMP dehydrogenase; SMART: CBS domain containing protein; SPTR: Inosine-5'-monophosphate dehydrogenase; TIGRFAM: inosine-5'-monophosphate dehydrogenase; PFAM: CBS domain; IMP dehydrogenase / GMP reductase domain; TIGRFAM: inosine-5'-monophosphate dehydrogenase YP_004159810.1 COGs: COG0514 Superfamily II DNA helicase; InterProIPR002121: IPR014021: IPR001650: IPR014001: IPR 011545: IPR018982: IPR006293: IPR018329; KEGG: bfs:BF3892 ATP-dependent DNA helicase; PFAM: RQC domain; helicase domain protein; DEAD/DEAH box helicase domain protein; HRDC domain protein; SMART: helicase domain protein; DEAD-like helicase; HRDC domain protein; SPTR: ATP-dependent DNA helicase RecQ; TIGRFAM: ATP-dependent DNA helicase RecQ; ATP-dependent DNA helicase, RecQ family; PFAM: Helicase conserved C-terminal domain; RQC domain; HRDC domain; DEAD/DEAH box helicase; TIGRFAM: ATP-dependent DNA helicase RecQ; ATP-dependent DNA helicase, RecQ family YP_004159811.1 COGs: COG1219 ATP-dependent protease Clp ATPase subunit; InterProIPR003593: IPR004487: IPR010603: IPR013093: IPR 019489; KEGG: bth:BT_3843 ATP-dependent protease ATP-binding subunit ClpX; PFAM: ATPase AAA; Clp ATPase-like; SMART: AAA ATPase; SPTR: ATP-dependent Clp protease ATP-binding subunit clpX; TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit ClpX; PFAM: AAA domain (Cdc48 subfamily); C-terminal, D2-small domain, of ClpB protein; ClpX C4-type zinc finger; TIGRFAM: endopeptidase Clp ATP-binding regulatory subunit (clpX) YP_004159812.1 COGs: COG0740 Protease subunit of ATP-dependent Clp protease; InterPro IPR001907; KEGG: bth:BT_3842 ATP-dependent Clp protease proteolytic subunit; PFAM: peptidase S14 ClpP; PRIAM: Endopeptidase Clp; SPTR: Clp protease; PFAM: Clp protease; TIGRFAM: ATP-dependent Clp protease, proteolytic subunit ClpP YP_004159813.1 COGs: COG0544 FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor); InterPro IPR008881: IPR005215; KEGG: bfs:BF3895 cell division trigger factor; PFAM: trigger factor domain-containing protein; SPTR: Trigger factor tig; TIGRFAM: trigger factor; PFAM: Bacterial trigger factor protein (TF); TIGRFAM: trigger factor YP_004159814.1 COGs: COG0724 RNA-binding protein (RRM domain); InterPro IPR000504; KEGG: bth:BT_3840 RNA-binding protein RbpA; PFAM: RNP-1 like RNA-binding protein; SMART: RNP-1 like RNA-binding protein; SPTR: uncharacterized protein; PFAM: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) YP_004159815.1 COGs: COG1137 ABC-type (unclassified) transport system ATPase component; InterPro IPR003439: IPR003593; KEGG: bfs:BF3898 ABC transport system, ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: uncharacterized protein; PFAM: ABC transporter YP_004159816.1 COGs: COG0767 ABC-type transport system involved in resistance to organic solvents permease component; InterPro IPR006162: IPR003453; KEGG: bfs:BF3899 hypothetical protein; PFAM: protein of unknown function DUF140; SPTR: uncharacterized protein; manually curated; PFAM: Domain of unknown function DUF140; TIGRFAM: conserved hypothetical integral membrane protein YP_004159817.1 COGs: COG1127 ABC-type transport system involved in resistance to organic solvents ATPase component; InterPro IPR003439: IPR003593: IPR017871; KEGG: bth:BT_3839 ABC transporter ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: uncharacterized protein; PFAM: ABC transporter YP_004159818.1 COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR000792: IPR001789; KEGG: bfs:BF3901 LuxR family regulatory protein; PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR; SPTR: uncharacterized protein; manually curated; PFAM: Response regulator receiver domain; Bacterial regulatory proteins, luxR family YP_004159819.1 COGs: COG1160 GTPase; InterPro IPR006073: IPR016484: IPR002917: IPR005225; KEGG: bth:BT_3836 GTP-binding protein EngA; PFAM: GTP-binding protein HSR1-related; SPTR: GTP-binding protein engA; TIGRFAM: ribosome-associated GTPase EngA; small GTP-binding protein; PFAM: GTPase of unknown function; TIGRFAM: ribosome-associated GTPase EngA; small GTP-binding protein domain YP_004159820.1 COGs: COG1159 GTPase; InterPro IPR004044: IPR005662: IPR002917: IPR005225; KEGG: bth:BT_3835 GTP-binding protein Era; PFAM: GTP-binding protein HSR1-related; KH type 2 domain protein; SPTR: GTP-binding protein era homolog; TIGRFAM: GTP-binding protein Era; small GTP-binding protein; manually curated; PFAM: GTPase of unknown function; KH domain; TIGRFAM: GTP-binding protein Era; small GTP-binding protein domain YP_004159821.1 COGs: COG0332 3-oxoacyl-ACP; InterPro IPR004655: IPR013751: IPR013747; KEGG: bth:BT_3834 3-oxoacyl-(ACP) synthase III; PFAM: 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III domain-containing protein; 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III; PRIAM: Beta-ketoacyl-acyl-carrier-protein synthase I; SPTR: 3-oxoacyl-[acyl-carrier-protein] synthase 3; TIGRFAM: 3-oxoacyl-ACP synthase III; PFAM: 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal; 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III; TIGRFAM: 3-oxoacyl-ACP synthase III YP_004159822.1 COGs: COG0333 Ribosomal protein L32; InterPro IPR002677; KEGG: bfr:BF4090 50S ribosomal protein L32; PFAM: ribosomal L32p protein; SPTR: 50S ribosomal protein L32; TIGRFAM: ribosomal protein L32; PFAM: Ribosomal L32p protein family; TIGRFAM: ribosomal protein L32 YP_004159823.1 InterPro IPR003772; KEGG: bfr:BF4091 hypothetical protein; PFAM: protein of unknown function DUF177; SPTR: uncharacterized protein; PFAM: Uncharacterized ACR, COG1399 YP_004159824.1 KEGG: bth:BT_1612 hypothetical protein; SPTR: uncharacterized protein YP_004159825.1 InterPro IPR007060; KEGG: bfs:BF3072 septum formation initiator-related protein; PFAM: Septum formation initiator; SPTR: uncharacterized protein; PFAM: Septum formation initiator YP_004159826.1 COGs: COG2812 DNA polymerase III gamma/tau subunits; InterPro IPR001270: IPR003593: IPR003959: IPR012763; KEGG: bfr:BF3231 DNA polymerase III subunit gamma/tau; PFAM: AAA ATPase central domain protein; SMART: AAA ATPase; SPTR: uncharacterized protein; TIGRFAM: DNA polymerase III, subunits gamma and tau; manually curated; PFAM: ATPase associated with various cellular activities (AAA); DNA polymerase III subunits gamma and tau domain III; TIGRFAM: DNA polymerase III, subunit gamma and tau YP_004159827.1 COGs: COG0642 Signal transduction histidine kinase; InterPro IPR005467: IPR004358: IPR003661: IPR003594; KEGG: bth:BT_1800 two-component system sensor histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: uncharacterized protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain YP_004159828.1 COGs: COG0642 Signal transduction histidine kinase; InterPro IPR005467: IPR003661; KEGG: bth:BT_1801 two-component system sensor histidine kinase; PFAM: histidine kinase A domain protein; SMART: histidine kinase A domain protein; SPTR: two-component system sensor histidine kinase; PFAM: His Kinase A (phosphoacceptor) domain YP_004159829.1 InterPro IPR017896: IPR017900: IPR000813; KEGG: bfr:BF0597 ferredoxin; SPTR: uncharacterized protein; PFAM: 4Fe-4S binding domain YP_004159830.1 COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR001176: IPR004838: IPR004839; KEGG: bfs:BF0545 aspartate aminotransferase; PFAM: aminotransferase class I and II; SPTR: Aspartate aminotransferase; PFAM: Aminotransferase class I and II YP_004159831.1 COGs: COG0108 3 4-dihydroxy-2-butanone 4-phosphate synthase; InterPro IPR000926: IPR000422: IPR016299; KEGG: bth:BT_2416 GTP cyclohydrolase II; PFAM: 34-dihydroxy-2-butanone 4-phosphate synthase; GTP cyclohydrolase II; SPTR: uncharacterized protein; TIGRFAM: 3,4-dihydroxy-2-butanone 4-phosphate synthase; GTP cyclohydrolase II; PFAM: GTP cyclohydrolase II; 3,4-dihydroxy-2-butanone 4-phosphate synthase; TIGRFAM: GTP cyclohydrolase II; 3,4-dihydroxy-2-butanone 4-phosphate synthase YP_004159832.1 COGs: COG0795 permease; InterPro IPR005495; KEGG: bfs:BF0543 permease; PFAM: permease YjgP/YjgQ family protein; SPTR: uncharacterized protein; manually curated; PFAM: Predicted permease YjgP/YjgQ family YP_004159833.1 KEGG: bth:BT_2418 hypothetical protein; SPTR: uncharacterized protein YP_004159834.1 COGs: COG5002 Signal transduction histidine kinase; InterProIPR005467: IPR000014: IPR003660: IPR004358: IPR 003661: IPR003594: IPR013767; KEGG: bfs:BF0533 two-component sensor histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; PAS fold domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; PAS domain containing protein; SPTR: uncharacterized protein; PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold YP_004159835.1 COGs: COG2205 Osmosensitive K+ channel histidine kinase; InterPro IPR020781: IPR003852; KEGG: bfs:BF0532 osmosensitive potassium transport sensor protein; PFAM: Osmosensitive K channel His kinase sensor; SPTR: uncharacterized protein; PFAM: Osmosensitive K+ channel His kinase sensor domain; Universal stress protein family YP_004159836.1 COGs: COG2156 K+-transporting ATPase c chain; InterPro IPR003820; KEGG: bth:BT_2423 potassium-transporting ATPase subunit C; PFAM: K transporting ATPase KdpC subunit; PRIAM: Potassium-transporting ATPase; SPTR: K+-transporting ATPase, C subunit; PFAM: K+-transporting ATPase, c chain; TIGRFAM: K+-transporting ATPase, C subunit YP_004159837.1 COGs: COG2216 High-affinity K+ transport system ATPase chain B; InterProIPR001757: IPR006391: IPR018247: IPR018303: IPR 000150: IPR008250: IPR005834; KEGG: bfs:BF0529 potassium-transporting ATPase B chain; PFAM: E1-E2 ATPase-associated domain protein; Haloacid dehalogenase domain protein hydrolase; SPTR: uncharacterized protein; TIGRFAM: K+-transporting ATPase, B subunit; ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase; haloacid dehalogenase-like hydrolase; TIGRFAM: K+-transporting ATPase, B subunit; ATPase, P-type (transporting), HAD superfamily, subfamily IC YP_004159838.1 COGs: COG2060 K+-transporting ATPase A chain; InterPro IPR004623; KEGG: bth:BT_2425 potassium-transporting ATPase subunit A; PFAM: K transporting ATPase A subunit; PRIAM: Potassium-transporting ATPase; SPTR: uncharacterized protein; TIGRFAM: potassium-transporting ATPase, A subunit; PFAM: Potassium-transporting ATPase A subunit; TIGRFAM: K+-transporting ATPase, KdpA YP_004159839.1 COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterProIPR002078: IPR001789: IPR020441: IPR003593: IPR 002197; KEGG: bfs:BF0527 two-component response regulator-like protein; PFAM: sigma-54 factor interaction domain-containing protein; response regulator receiver; helix-turn-helix Fis-type; SMART: response regulator receiver; AAA ATPase; SPTR: uncharacterized protein; PFAM: Response regulator receiver domain; Bacterial regulatory protein, Fis family; Sigma-54 interaction domain YP_004159840.1 KEGG: bay:RBAM_026730 phi ETA orf 55-like protein; SPTR: uncharacterized protein; PFAM: GDSL-like Lipase/Acylhydrolase YP_004159841.1 COGs: COG2942 N-acyl-D-glucosamine 2-epimerase; InterPro IPR010819; KEGG: bfr:BF0849 N-acyl-D-glucosamine 2-epimerase; PFAM: N-acylglucosamine 2-epimerase; SPTR: uncharacterized protein; PFAM: N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) YP_004159842.1 COGs: COG2211 Na+/melibiose symporter and related transporter; InterPro IPR011701: IPR001927; KEGG: bfs:BF0773 cation symporter; PFAM: major facilitator superfamily MFS_1; SPTR: uncharacterized protein; TIGRFAM: sugar (glycoside-Pentoside-Hexuronide) transporter; PFAM: Major Facilitator Superfamily; TIGRFAM: sugar (glycoside-Pentoside-Hexuronide) transporter YP_004159843.1 COGs: COG2152 glycosylase; InterPro IPR007184; KEGG: pdi:BDI_0059 hypothetical protein; PFAM: glycosidase related protein; SPTR: uncharacterized protein; PFAM: Domain of unknown function (DUF377) YP_004159844.1 COGs: COG4124 Beta-mannanase; InterPro IPR000805: IPR016714; KEGG: pdi:BDI_0060 beta-glycosidase; PRIAM: Mannan endo-1,4-beta-mannosidase; SPTR: glycoside hydrolase 26 protein; PFAM: glycosyl hydrolase 26 YP_004159845.1 InterPro IPR011659; KEGG: pdi:BDI_0062 hypothetical protein; PFAM: hypothetical protein; SPTR: uncharacterized protein; PFAM: WD40-like Beta Propeller Repeat YP_004159846.1 KEGG: pdi:BDI_0063 transmembrane protein; SPTR: uncharacterized protein YP_004159847.1 KEGG: pdi:BDI_0085 hypothetical protein; SPTR: uncharacterized protein YP_004159848.1 InterPro IPR012944; KEGG: pdi:BDI_0086 hypothetical protein; PFAM: RagB/SusD domain protein; SPTR: uncharacterized protein; PFAM: SusD family YP_004159849.1 InterPro IPR012910: IPR000531; KEGG: pdi:BDI_0087 hypothetical protein; PFAM: TonB-dependent receptor; TonB-dependent receptor plug; SPTR: uncharacterized protein; PFAM: TonB dependent receptor; TonB-dependent Receptor Plug Domain YP_004159850.1 COGs: COG3934 Endo-beta-mannanase; KEGG: bfr:BF0840 endo-1,4-beta-mannosidase; PRIAM: Mannan endo-1,4-beta-mannosidase; SPTR: uncharacterized protein; PFAM: Cellulase (glycosyl hydrolase 5) YP_004159851.1 COGs: COG3458 Acetyl esterase (deacetylase); InterPro IPR008391; KEGG: pru:PRU_1726 family 7 carbohydrate esterase; PFAM: Acetyl xylan esterase; SPTR: uncharacterized protein; PFAM: Acetyl xylan esterase (AXE1) YP_004159852.1 COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR018060: IPR020449: IPR018062: IPR000005; KEGG: bfs:BF0723 AraC family transcriptional regulator; PFAM: helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: uncharacterized protein; PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family YP_004159853.1 COGs: COG3250 Beta-galactosidase/beta-glucuronidase; InterPro IPR006101: IPR006104: IPR006102: IPR006103; KEGG: pru:PRU_2769 family 2 glycosyl hydrolase; PFAM: glycoside hydrolase 2 sugar binding; glycoside hydrolase 2 immunoglobulin domain protein beta-sandwich; glycoside hydrolase 2; PRIAM: Beta-galactosidase; SPTR: uncharacterized protein; PFAM: domain; glycosyl hydrolases family 2, TIM barrel domain; glycosyl hydrolases family 2, sugar binding domain YP_004159854.1 COGs: COG1472 Beta-glucosidase-related glycosidase; InterPro IPR001764: IPR019800: IPR002772; KEGG: sus:Acid_2679 glycoside hydrolase 3 protein; PFAM: glycoside hydrolase 3; SPTR: Xylosidase/arabinosidase; PFAM: glycosyl hydrolase 3 C terminal domain; glycosyl hydrolase 3 N terminal domain YP_004159855.1 COGs: COG0667 oxidoreductase (related to aryl-alcohol dehydrogenase); InterPro IPR001395; KEGG: bfs:BF0757 aldo/keto-reductase; PFAM: aldo/keto reductase; SPTR: uncharacterized protein; PFAM: Aldo/keto reductase YP_004159856.1 InterPro IPR019563; KEGG: fjo:Fjoh_4959 hypothetical protein; PFAM: glycoside hydrolase 97; SPTR: uncharacterized protein; PFAM: glycoside hydrolase 97 YP_004159857.1 InterPro IPR012910: IPR000531; KEGG: bfs:BF4256 outer membrane protein; PFAM: TonB-dependent receptor plug; TonB-dependent receptor; SPTR: outer membrane protein probably involved in nutrient binding; PFAM: TonB dependent receptor; TonB-dependent Receptor Plug Domain YP_004159858.1 InterPro IPR012944; KEGG: bfs:BF4257 hypothetical protein; PFAM: RagB/SusD domain protein; SPTR: uncharacterized protein; PFAM: SusD family YP_004159860.1 COGs: COG1472 Beta-glucosidase-related glycosidase; InterPro IPR001764: IPR001466; KEGG: bfr:BF0567 beta-N-acetylglucosaminidase; PFAM: glycoside hydrolase 3; beta-lactamase; SPTR: uncharacterized protein; PFAM: glycosyl hydrolase 3 N terminal domain; Beta-lactamase YP_004159861.1 COGs: COG1680 Beta-lactamase class C and other penicillin binding protein; InterPro IPR001764: IPR001466; KEGG: bfr:BF0566 beta-N-acetylglucosaminidase; PFAM: beta-lactamase; glycoside hydrolase 3; SPTR: uncharacterized protein; PFAM: glycosyl hydrolase 3 N terminal domain; Beta-lactamase YP_004159862.1 COGs: COG0737 5'-nucleotidase/2' 3'-cyclic phosphodiesterase and related esterase; InterPro IPR006179: IPR010916: IPR006146: IPR004843; KEGG: bfs:BF0515 secreted 5'-nucleotidase; PFAM: metallophosphoesterase; SPTR: uncharacterized protein; PFAM: Calcineurin-like phosphoesterase YP_004159863.1 COGs: COG0737 5'-nucleotidase/2' 3'-cyclic phosphodiesterase and related esterase; InterPro IPR006179: IPR008334; KEGG: bfs:BF0514 5'nucleotidase/UDP-sugar hydrolase; PFAM: 5'-Nucleotidase domain-containing protein; SPTR: uncharacterized protein; PFAM: 5'-nucleotidase, C-terminal domain YP_004159864.1 COGs: COG0335 Ribosomal protein L19; InterPro IPR001857: IPR018257; KEGG: bfs:BF0513 50S ribosomal protein L19; PFAM: ribosomal protein L19; SPTR: 50S ribosomal protein L19; TIGRFAM: ribosomal protein L19; PFAM: Ribosomal protein L19; TIGRFAM: ribosomal protein L19, bacterial type YP_004159865.1 COGs: COG3264 Small-conductance mechanosensitive channel; InterPro IPR006685; KEGG: pru:PRU_1625 mechanosensitive ion channel family protein; PFAM: MscS Mechanosensitive ion channel; SPTR: MscS Mechanosensitive ion channel; PFAM: Mechanosensitive ion channel YP_004159866.1 COGs: COG3279 Response regulator of the LytR/AlgR family; InterPro IPR001789: IPR007492; KEGG: bvu:BVU_3800 two-component system response regulator; PFAM: response regulator receiver; LytTr DNA-binding region; SMART: response regulator receiver; SPTR: uncharacterized protein; PFAM: Response regulator receiver domain; LytTr DNA-binding domain YP_004159867.1 COGs: COG3275 regulator of cell autolysis; InterPro IPR019734: IPR010559: IPR003594; KEGG: bfr:BF0088 two-component system sensor histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase internal region; SPTR: uncharacterized protein; manually curated; PFAM: Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase YP_004159868.1 COGs: COG0642 Signal transduction histidine kinase; InterPro IPR005467: IPR004358: IPR003661: IPR003594; KEGG: bfr:BF0293 two-component system sensor histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: uncharacterized protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain YP_004159869.1 COGs: COG0642 Signal transduction histidine kinase; InterPro IPR019734: IPR005467: IPR013026: IPR003661; KEGG: bth:BT_1598 two-component system sensor histidine kinase; PFAM: histidine kinase A domain protein; SMART: histidine kinase A domain protein; Tetratricopeptide repeat; SPTR: uncharacterized protein; PFAM: His Kinase A (phosphoacceptor) domain YP_004159870.1 COGs: COG1940 Transcriptional regulator/sugar kinase; InterPro IPR000600; KEGG: bth:BT_2493 ROK family transcriptional repressor; PFAM: ROK family protein; SPTR: uncharacterized protein; PFAM: ROK family; TIGRFAM: ROK family protein ( glucokinase) YP_004159871.1 COGs: COG1136 ABC-type antimicrobial peptide transport system ATPase component; InterPro IPR003439: IPR003593: IPR017871; KEGG: bfr:BF0561 ABC transporter ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: uncharacterized protein; PFAM: ABC transporter YP_004159872.1 COGs: COG0577 ABC-type antimicrobial peptide transport system permease component; InterPro IPR003838; KEGG: bfs:BF0510 ABC transporter; PFAM: protein of unknown function DUF214; SPTR: uncharacterized protein; PFAM: Predicted permease YP_004159873.1 COGs: COG0577 ABC-type antimicrobial peptide transport system permease component; InterPro IPR003838; KEGG: bfs:BF0509 ATP-binding component of ABC transporter; PFAM: protein of unknown function DUF214; SPTR: uncharacterized protein; PFAM: Predicted permease YP_004159874.1 COGs: COG0845 Membrane-fusion protein; InterPro IPR006143; KEGG: bfr:BF0558 membrane fusion efflux protein; PFAM: hemolysin D; SPTR: uncharacterized protein; TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: HlyD family secretion protein; TIGRFAM: RND family efflux transporter, MFP subunit YP_004159875.1 COGs: COG1538 Outer membrane protein; InterPro IPR003423; KEGG: bfr:BF0557 outer membrane efflux protein; PFAM: outer membrane efflux protein; SPTR: uncharacterized protein; PFAM: Outer membrane efflux protein YP_004159876.1 COGs: COG0744 Membrane carboxypeptidase (penicillin-binding protein); InterPro IPR001264; KEGG: bth:BT_2501 penicillin-binding protein; PFAM: glycosyl transferase 51; SPTR: uncharacterized protein; PFAM: Transglycosylase YP_004159877.1 KEGG: bfs:BF0494 hypothetical protein; SPTR: uncharacterized protein YP_004159878.1 KEGG: bfr:BF0543 hypothetical protein; SPTR: uncharacterized protein YP_004159879.1 COGs: COG2996 conserved hypothetical protein; InterPro IPR014464; KEGG: bfs:BF0491 hypothetical protein; SPTR: uncharacterized protein YP_004159880.1 COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR018060: IPR018062: IPR000005; KEGG: pdi:BDI_0990 transcriptional regulator; PFAM: helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: transcriptional regulator; PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family YP_004159881.1 COGs: COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)protein; InterPro IPR006665: IPR006664; KEGG: pdi:BDI_0996 outer membrane lipoprotein; PFAM: OmpA/MotB domain protein; SPTR: Outer membrane protein, OmpA domain protein; PFAM: OmpA family YP_004159882.1 KEGG: pth:PTH_1458 membrane-fusion protein; SPTR: Membrane-fusion protein YP_004159883.1 KEGG: dre:100330007 GTPase, IMAP family member 4-like; SPTR: Chromosome segregation ATPases YP_004159884.1 KEGG: pdi:BDI_1009 hypothetical protein; SPTR: uncharacterized protein YP_004159885.1 KEGG: pdi:BDI_1010 hypothetical protein; SPTR: uncharacterized protein; PFAM: Chloroplast import component protein (Tic20) YP_004159886.1 COGs: COG0039 Malate/lactate dehydrogenase; InterPro IPR001236: IPR001557; KEGG: bvu:BVU_0462 malate dehydrogenase; PFAM: Lactate/malate dehydrogenase; SPTR: uncharacterized protein; PFAM: lactate/malate dehydrogenase, alpha/beta C-terminal domain; lactate/malate dehydrogenase, NAD binding domain YP_004159887.1 InterPro IPR000421; KEGG: bfs:BF2939 lipoprotein; PFAM: coagulation factor 5/8 type domain protein; SPTR: uncharacterized protein; PFAM: F5/8 type C domain YP_004159888.1 InterPro IPR003961; KEGG: bfs:BF2940 hypothetical protein; SPTR: uncharacterized protein YP_004159889.1 InterPro IPR012944; KEGG: bfs:BF2941 hypothetical protein; PFAM: RagB/SusD domain protein; SPTR: uncharacterized protein; PFAM: SusD family YP_004159890.1 InterPro IPR012910: IPR000531; KEGG: bfs:BF2942 hypothetical protein; PFAM: TonB-dependent receptor; TonB-dependent receptor plug; SPTR: exported protein; PFAM: TonB-dependent Receptor Plug Domain; TonB dependent receptor YP_004159891.1 COGs: COG3712 Fe2+-dicitrate sensor membrane component; InterPro IPR006860: IPR012373; KEGG: bfr:BF3782 anti-sigma factor; PFAM: FecR protein; SPTR: anti-sigma factor; PFAM: FecR protein YP_004159892.1 COGs: COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog; InterPro IPR007627: IPR013249: IPR014284: IPR014327; KEGG: fjo:Fjoh_4791 ECF subfamily RNA polymerase sigma-24 factor; PFAM: Sigma-70 region 4 type 2; sigma-70 region 2 domain protein; SPTR: uncharacterized protein; TIGRFAM: RNA polymerase sigma-70 factor; RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; RNA polymerase sigma-70 factor, Bacteroides expansion family 1 YP_004159893.1 KEGG: bth:BT_2538 hypothetical protein; SPTR: uncharacterized protein; TIGRFAM: DNA-binding protein, histone-like YP_004159894.1 COGs: COG1438 Arginine repressor; InterPro IPR001669: IPR020899; KEGG: bfr:BF0535 transcriptional regulator of arginine metabolism; PFAM: Arginine repressor-like; SPTR: uncharacterized protein; TIGRFAM: arginine repressor; PFAM: Arginine repressor, C-terminal domain; Arginine repressor, DNA binding domain; TIGRFAM: arginine repressor YP_004159895.1 KEGG: bvu:BVU_0593 hypothetical protein; SPTR: uncharacterized protein; manually curated YP_004159896.1 COGs: COG0137 Argininosuccinate synthase; InterPro IPR018223: IPR001518; KEGG: bth:BT_3760 argininosuccinate synthase; PFAM: argininosuccinate synthase; PRIAM: Argininosuccinate synthase; SPTR: uncharacterized protein; PFAM: Arginosuccinate synthase; TIGRFAM: argininosuccinate synthase YP_004159897.1 COGs: COG1983 stress-responsive transcriptional regulator protein; InterPro IPR007168; KEGG: bth:BT_1609 hypothetical protein; PFAM: PspC domain protein; SPTR: uncharacterized protein; PFAM: PspC domain YP_004159898.1 COGs: COG0002 Acetylglutamate semialdehyde dehydrogenase; InterPro IPR000706: IPR000534: IPR012280; KEGG: bfs:BF0480 N-acetyl-gamma-glutamyl-phosphate reductase; PFAM: Semialdehyde dehydrogenase NAD - binding; Semialdehyde dehydrogenase dimerisation region; PRIAM: N-acetyl-gamma-glutamyl-phosphate reductase; SPTR: N-acetyl-gamma-glutamyl-phosphate reductase; TIGRFAM: N-acetyl-gamma-glutamyl-phosphate reductase; PFAM: Semialdehyde dehydrogenase, dimerisation domain; Semialdehyde dehydrogenase, NAD binding domain; TIGRFAM: N-acetyl-gamma-glutamyl-phosphate reductase, common form YP_004159899.1 COGs: COG4992 Ornithine/acetylornithine aminotransferase; InterPro IPR005814; KEGG: bth:BT_3758 acetylornithine aminotransferase; PFAM: aminotransferase class-III; SPTR: uncharacterized protein; PFAM: Aminotransferase class-III YP_004159900.1 KEGG: bth:BT_1460 hypothetical protein; SPTR: Prevent-host-death family protein YP_004159901.1 COGs: COG3275 regulator of cell autolysis; InterPro IPR010559; KEGG: bth:BT_1459 two-component system sensor; PFAM: histidine kinase internal region; SPTR: uncharacterized protein; PFAM: Histidine kinase YP_004159902.1 COGs: COG3275 regulator of cell autolysis; InterPro IPR010559; KEGG: bth:BT_1458 two-component system sensor histidine kinase; PFAM: histidine kinase internal region; SPTR: uncharacterized protein; PFAM: Histidine kinase YP_004159903.1 COGs: COG3279 Response regulator of the LytR/AlgR family; InterPro IPR001789: IPR007492; KEGG: bth:BT_1457 two-component system response regulator; PFAM: response regulator receiver; LytTr DNA-binding region; SMART: response regulator receiver; SPTR: two-component system response regulator; PFAM: Response regulator receiver domain; LytTr DNA-binding domain YP_004159904.1 KEGG: pkn:PKH_060900 hypothetical protein; SPTR: lipoprotein YP_004159905.1 COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR000792; KEGG: fjo:Fjoh_0173 response regulator receiver protein; PFAM: regulatory protein LuxR; SMART: regulatory protein LuxR; SPTR: uncharacterized protein; PFAM: Bacterial regulatory proteins, luxR family YP_004159906.1 KEGG: fjo:Fjoh_0174 hypothetical protein; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF1349) YP_004159907.1 InterPro IPR000182; KEGG: shi:Shel_25620 acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: Na+/H+ antiporter NhaC; PFAM: Acetyltransferase (GNAT) family YP_004159908.1 COGs: COG1020 Non-ribosomal peptide synthetase modules and related protein; InterPro IPR020459: IPR020845: IPR000873: IPR010071; KEGG: shi:Shel_25610 amino acid adenylation enzyme/thioester reductase; PFAM: AMP-dependent synthetase and ligase; SPTR: Bacitracin synthetase 2 (BA2); TIGRFAM: amino acid adenylation protein; PFAM: AMP-binding enzyme; TIGRFAM: amino acid adenylation domain YP_004159909.1 COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR018060: IPR000005; KEGG: bth:BT_1385 transcriptional regulator; PFAM: helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: Transcriptional regulator; PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family YP_004159910.1 KEGG: bvu:BVU_0429 hypothetical protein; SPTR: uncharacterized protein YP_004159911.1 KEGG: bvu:BVU_1438 hypothetical protein; SPTR: Predicted protein YP_004159912.1 COGs: COG0345 Pyrroline-5-carboxylate reductase; InterPro IPR004455: IPR000304; KEGG: bvu:BVU_0589 pyrroline-5-carboxylate reductase; PFAM: NADP oxidoreductase coenzyme F420-dependent; PRIAM: Pyrroline-5-carboxylate reductase; SPTR: Pyrroline-5-carboxylate reductase; TIGRFAM: pyrroline-5-carboxylate reductase; PFAM: NADP oxidoreductase coenzyme F420-dependent; TIGRFAM: pyrroline-5-carboxylate reductase YP_004159913.1 COGs: COG0642 Signal transduction histidine kinase; InterProIPR005467: IPR000700: IPR004358: IPR001610: IPR 003661: IPR003594: IPR013656: IPR013655; KEGG: bth:BT_0818 two-component system sensor histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAC repeat-containing protein; SPTR: uncharacterized protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box YP_004159914.1 InterPro IPR001387: IPR013096; KEGG: bfs:BF0477 regulatory protein; PFAM: cupin; hypothetical protein; SMART: hypothetical protein; SPTR: uncharacterized protein; PFAM: Cupin domain; Helix-turn-helix YP_004159915.1 COGs: COG0365 Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; InterPro IPR020845: IPR000873; KEGG: bvu:BVU_0574 acetyl-coenzyme A synthetase; PFAM: AMP-dependent synthetase and ligase; SPTR: AMP-binding enzyme; PFAM: AMP-binding enzyme YP_004159916.1 InterPro IPR017441; KEGG: bvu:BVU_0479 hypothetical protein; SPTR: uncharacterized protein; PFAM: Lipid A 3-O-deacylase (PagL) YP_004159917.1 InterPro IPR018873; KEGG: bfs:BF4124 hypothetical protein; PFAM: KilA-N, DNA-binding domain; SPTR: uncharacterized protein; PFAM: ORF6N domain YP_004159918.1 InterPro IPR010260; KEGG: cat:CA2559_11658 hypothetical protein; PFAM: Prophage CP4-57 regulatory; SPTR: Excisionase DNA binding domain-containing protein YP_004159919.1 KEGG: cth:Cthe_2466 hypothetical protein; SPTR: uncharacterized protein YP_004159920.1 KEGG: ate:Athe_2486 hypothetical protein; SPTR: uncharacterized protein YP_004159921.1 KEGG: sli:Slin_3285 hypothetical protein; SPTR: uncharacterized protein YP_004159922.1 KEGG: ppe:PEPE_0068 hypothetical protein; SPTR: uncharacterized protein YP_004159923.1 KEGG: zpr:ZPR_3619 GTP-binding protein TypA; SPTR: GTP-binding protein TypA YP_004159924.1 KEGG: pca:Pcar_1785 hypothetical protein; SPTR: uncharacterized protein YP_004159925.1 KEGG: ljf:FI9785_681 Xaa-Pro dipeptidyl-peptidase; SPTR: Xaa-Pro dipeptidyl-peptidase YP_004159926.1 InterPro IPR001387; KEGG: bth:BT_4733 hypothetical protein; PFAM: hypothetical protein; SMART: hypothetical protein; SPTR: Transcriptional regulator; PFAM: Helix-turn-helix YP_004159927.1 InterPro IPR009241; KEGG: bth:BT_4732 hypothetical protein; PFAM: protein of unknown function DUF891; SPTR: uncharacterized protein; PFAM: Phage derived protein Gp49-like (DUF891) YP_004159928.1 InterPro IPR001387; KEGG: bfs:BF0462 regulatory protein; PFAM: hypothetical protein; SMART: hypothetical protein; SPTR: Regulatory protein; PFAM: Helix-turn-helix YP_004159929.1 KEGG: hse:Hsero_1330 aerotaxis sensor receptor transmembrane protein YP_004159930.1 COGs: COG0165 Argininosuccinate lyase; InterPro IPR009049: IPR020557: IPR003031: IPR000362; KEGG: bth:BT_3733 argininosuccinate lyase; PFAM: fumarate lyase; SPTR: Argininosuccinate lyase; TIGRFAM: argininosuccinate lyase; PFAM: Lyase; TIGRFAM: argininosuccinate lyase YP_004159931.1 KEGG: bfs:BF0456 hypothetical protein; SPTR: uncharacterized protein; PFAM: polyketide cyclase / dehydrase and lipid transport YP_004159932.1 COGs: COG0461 Orotate phosphoribosyltransferase; InterPro IPR004467: IPR000836; KEGG: bfs:BF0455 orotate phosphoribosyltransferase; PFAM: phosphoribosyltransferase; SPTR: Orotate phosphoribosyltransferase; TIGRFAM: orotate phosphoribosyltransferase; PFAM: phosphoribosyl transferase domain; TIGRFAM: orotate phosphoribosyltransferase YP_004159933.1 COGs: COG2137 conserved hypothetical protein; InterPro IPR003783; KEGG: bth:BT_3730 regulatory protein; PFAM: regulatory protein RecX; SPTR: uncharacterized protein; PFAM: RecX family YP_004159934.1 COGs: COG2890 methylase of polypeptide chain release factors; InterPro IPR004556: IPR019874: IPR002052: IPR007848; KEGG: bfr:BF0508 protoporphyrinogen oxidase; PFAM: methyltransferase small; SPTR: uncharacterized protein; TIGRFAM: protein-(glutamine-N5) methyltransferase, release factor-specific; modification methylase, HemK family; manually curated; PFAM: methyltransferase small domain; TIGRFAM: HemK family methylases; protein-(glutamine-N5) methyltransferase, release factor-specific YP_004159935.1 COGs: COG0117 Pyrimidine deaminase; InterPro IPR004794: IPR016192: IPR002125: IPR002734; KEGG: bfs:BF0452 riboflavin biosynthesis protein [includes: diaminohydroxyphosphoribosylaminopyrimidine deaminase; PFAM: CMP/dCMP deaminase zinc-binding; bifunctional deaminase-reductase domain protein; SPTR: Riboflavin biosynthesis protein RibD; TIGRFAM: riboflavin biosynthesis protein RibD; PFAM: RibD C-terminal domain; Cytidine and deoxycytidylate deaminase zinc-binding region; TIGRFAM: riboflavin-specific deaminase C-terminal domain; riboflavin biosynthesis protein RibD YP_004159936.1 KEGG: bfs:BF0451 hypothetical protein; SPTR: uncharacterized protein YP_004159937.1 COGs: COG0020 UDP pyrophosphate synthase; InterPro IPR001441: IPR018520; KEGG: bfs:BF0450 UDP pyrophosphate synthase; PFAM: Di-trans-poly-cis-decaprenylcistransferase; PRIAM: Di-trans,poly-cis-decaprenylcistransferase; SPTR: Di-trans,poly-cis-decaprenylcistransferase; TIGRFAM: UDP diphosphate synthase; manually curated; PFAM: UDP diphosphate synthase; TIGRFAM: UDP diphosphate synthase YP_004159938.1 COGs: COG4775 Outer membrane protein/protective antigen OMA87; InterPro IPR016474: IPR010827: IPR000184; KEGG: bfs:BF0449 outer membrane protein; PFAM: surface antigen (D15); surface antigen variable number repeat-containing protein; SPTR: Outer membrane protein assembly complex, YaeT protein; TIGRFAM: outer membrane protein assembly complex, YaeT protein; PFAM: Surface antigen variable number repeat; TIGRFAM: outer membrane protein assembly complex, YaeT protein YP_004159939.1 COGs: COG2825 Outer membrane protein; InterPro IPR005632; KEGG: bfs:BF0448 cationic 19 kDa outer membrane protein precursor; PFAM: outer membrane chaperone Skp (OmpH); SPTR: uncharacterized protein; PFAM: Outer membrane protein (OmpH-like) YP_004159940.1 InterPro IPR005632; KEGG: bfs:BF0447 outer membrane protein; PFAM: outer membrane chaperone Skp (OmpH); SPTR: uncharacterized protein; PFAM: Outer membrane protein (OmpH-like) YP_004159941.1 COGs: COG0796 Glutamate racemase; InterPro IPR004391: IPR018187: IPR015942; KEGG: bfs:BF0446 glutamate racemase; PFAM: Asp/Glu/hydantoin racemase; PRIAM: Glutamate racemase; SPTR: Glutamate racemase; TIGRFAM: glutamate racemase; PFAM: Asp/Glu/Hydantoin racemase; TIGRFAM: glutamate racemase YP_004159942.1 KEGG: bfs:BF0445 hypothetical protein; SPTR: uncharacterized protein YP_004159943.1 COGs: COG0263 Glutamate 5-kinase; InterProIPR005715: IPR011529: IPR019797: IPR002478: IPR 001057: IPR001048; KEGG: bth:BT_3719 gamma-glutamyl kinase; PFAM: aspartate/glutamate/uridylate kinase; PUA domain containing protein; SMART: PUA domain containing protein; SPTR: uncharacterized protein; TIGRFAM: glutamate 5-kinase; PFAM: PUA domain; Amino acid kinase; TIGRFAM: glutamate 5-kinase YP_004159944.1 COGs: COG0014 Gamma-glutamyl phosphate reductase; InterPro IPR000965: IPR012134: IPR020593; KEGG: bfs:BF0443 gamma-glutamyl phosphate reductase; PRIAM: Glutamate-5-semialdehyde dehydrogenase; SPTR: Gamma-glutamyl phosphate reductase; TIGRFAM: gamma-glutamyl phosphate reductase; TIGRFAM: gamma-glutamyl phosphate reductase YP_004159945.1 COGs: COG0078 Ornithine carbamoyltransferase; InterPro IPR006130: IPR002082: IPR006132: IPR006131; KEGG: bth:BT_3717 ornithine carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; SPTR: uncharacterized protein; PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain YP_004159946.1 COGs: COG0607 Rhodanese-related sulfurtransferase; InterPro IPR001763; KEGG: bfr:BF0493 hypothetical protein; PFAM: Rhodanese domain protein; SMART: Rhodanese domain protein; SPTR: uncharacterized protein; PFAM: Rhodanese-like domain YP_004159947.1 KEGG: bfs:BF0437 hypothetical protein; SPTR: uncharacterized protein YP_004159948.1 KEGG: bth:BT_3714 hypothetical protein; SPTR: uncharacterized protein YP_004159949.1 COGs: COG1181 D-alanine-D-alanine ligase and related ATP-grasp protein; InterProIPR005905: IPR000291: IPR011761: IPR011127: IPR 011095; KEGG: bth:BT_3713 D-alanyl-alanine synthetase A; PFAM: D-alanine--D-alanine ligase domain protein; PRIAM: D-alanine--D-alanine ligase; SPTR: D-alanine--D-alanine ligase; TIGRFAM: D-alanine/D-alanine ligase; PFAM: D-ala D-ala ligase C-terminus; D-ala D-ala ligase N-terminus; TIGRFAM: D-alanine--D-alanine ligase YP_004159950.1 COGs: COG0564 Pseudouridylate synthase 23S RNA-specific; InterPro IPR006225: IPR006224: IPR002942: IPR006145; KEGG: bfs:BF0434 ribosomal large subunit pseudouridine synthase; PFAM: pseudouridine synthase; RNA-binding S4 domain protein; SMART: RNA-binding S4 domain protein; SPTR: Pseudouridine synthase; TIGRFAM: pseudouridine synthase, RluA family; PFAM: RNA pseudouridylate synthase; S4 domain; TIGRFAM: pseudouridine synthase, RluA family YP_004159951.1 COGs: COG2815 conserved hypothetical protein; InterPro IPR005543; KEGG: bth:BT_3711 hypothetical protein; PFAM: PASTA domain containing protein; SMART: PASTA domain containing protein; SPTR: uncharacterized protein; manually curated; PFAM: PASTA domain YP_004159952.1 InterPro IPR000271: IPR020939; KEGG: bfs:BF0432 50S ribosomal protein L34; PFAM: ribosomal protein L34; SPTR: 50S ribosomal protein L34; TIGRFAM: ribosomal protein L34; manually curated; PFAM: Ribosomal protein L34; TIGRFAM: ribosomal protein L34, bacterial type YP_004159953.1 COGs: COG0231 Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A); InterProIPR011768: IPR020599: IPR013852: IPR013185: IPR 001059: IPR015365; KEGG: bvu:BVU_0529 elongation factor P; PFAM: Elongation factor KOW-like domain-containing protein; Elongation factor P/YeiP protein; Elongation factor P; SPTR: Elongation factor P; TIGRFAM: translation elongation factor P; PFAM: Elongation factor P, C-terminal; Elongation factor P (EF-P) KOW-like domain; Elongation factor P (EF-P) OB domain; TIGRFAM: translation elongation factor P YP_004159954.1 COGs: COG1215 glycosyltransferase probably involved in cell wall biogenesis; InterPro IPR001173; KEGG: bfs:BF0429 glycosyltransferase; PFAM: glycosyl transferase 2; SPTR: uncharacterized protein; PFAM: glycosyl transferase 2 YP_004159955.1 COGs: COG2003 DNA repair protein; InterPro IPR001405: IPR020891: IPR020854; KEGG: bfr:BF0483 DNA repair protein; PFAM: DNA repair protein RadC; SPTR: uncharacterized protein; TIGRFAM: DNA repair protein RadC; PFAM: Protein of unknown function (DUF2466); TIGRFAM: DNA repair protein radc YP_004159956.1 KEGG: bcy:Bcer98_2698 lipoprotein; SPTR: Lipoprotein YP_004159957.1 KEGG: asa:ASA_3538 hypothetical protein; SPTR: Protein containing PDZ domain YP_004159958.1 KEGG: mmq:MmarC5_1321 hypothetical protein; SPTR: uncharacterized protein YP_004159959.1 KEGG: bfr:BF0465 hypothetical protein; SPTR: uncharacterized protein YP_004159960.1 KEGG: ppr:PBPRA1021 ToxS; SPTR: ToxS YP_004159961.1 InterPro IPR003961: IPR000421; KEGG: bth:BT_3014 chitobiase; PFAM: coagulation factor 5/8 type domain protein; Fibronectin type III domain protein; SPTR: uncharacterized protein; PFAM: F5/8 type C domain; Fibronectin type III domain YP_004159962.1 InterPro IPR012944; KEGG: bfs:BF2941 hypothetical protein; PFAM: RagB/SusD domain protein; SPTR: uncharacterized protein; PFAM: SusD family YP_004159963.1 InterPro IPR012910: IPR000531; KEGG: bfs:BF2942 hypothetical protein; PFAM: TonB-dependent receptor plug; TonB-dependent receptor; SPTR: exported protein; PFAM: TonB-dependent Receptor Plug Domain; TonB dependent receptor YP_004159965.1 COGs: COG2151 metal-sulfur cluster biosynthetic protein; InterPro IPR002744; KEGG: bfs:BF0426 hypothetical protein; PFAM: protein of unknown function DUF59; SPTR: uncharacterized protein; manually curated; PFAM: Domain of unknown function DUF59; TIGRFAM: FeS assembly SUF system protein YP_004159966.1 COGs: COG2908 conserved hypothetical protein; InterPro IPR004843; KEGG: bth:BT_3697 UDP-2,3-diacylglucosamine hydrolase; PFAM: metallophosphoesterase; SPTR: uncharacterized protein YP_004159967.1 COGs: COG1785 Alkaline phosphatase; InterPro IPR018299: IPR001952; KEGG: bfr:BF0480 alkaline phosphatase III precursor; PFAM: Alkaline phosphatase; SMART: Alkaline phosphatase; SPTR: uncharacterized protein; PFAM: Alkaline phosphatase YP_004159968.1 COGs: COG0282 Acetate kinase; InterPro IPR004372: IPR000890; KEGG: bvu:BVU_0524 acetate kinase; PFAM: acetate and butyrate kinase; SPTR: Acetate kinase; TIGRFAM: acetate kinase; PFAM: Acetokinase; TIGRFAM: acetate kinase YP_004159969.1 COGs: COG0280 phosphotransacetylase; InterPro IPR004614: IPR012147: IPR002505; KEGG: bfs:BF0423 phosphate acetyltransferase; PFAM: phosphate acetyl/butaryl transferase; PRIAM: phosphate acetyltransferase; SPTR: phosphate acetyltransferase; TIGRFAM: phosphate acetyltransferase; PFAM: phosphate acetyl/butaryl transferase; TIGRFAM: phosphate acetyltransferase YP_004159970.1 KEGG: bfs:BF0422 hypothetical protein; SPTR: uncharacterized protein YP_004159971.1 KEGG: bfs:BF0420 hypothetical protein; SPTR: uncharacterized protein YP_004159972.1 InterPro IPR003961; KEGG: bfs:BF4095 hypothetical protein; PFAM: Fibronectin type III domain protein; SPTR: Predicted protein; PFAM: The GLUG motif YP_004159973.1 InterPro IPR013229; KEGG: cts:Ctha_2276 PEGA domain protein; PFAM: PEGA domain protein; SPTR: PEGA domain protein; PFAM: PEGA domain YP_004159974.1 COGs: COG1380 effector of murein hydrolase LrgA; InterPro IPR005538; KEGG: bfs:BF0418 transmembrane holin-like protein LrgA; PFAM: LrgA family protein; SPTR: uncharacterized protein; PFAM: LrgA family YP_004159975.1 COGs: COG1346 effector of murein hydrolase; InterPro IPR007300; KEGG: bfs:BF0417 LrgB family transmembrane protein; PFAM: LrgB family protein; SPTR: uncharacterized protein; PFAM: LrgB-like family; TIGRFAM: conserved hypothetical protein TIGR00659 YP_004159976.1 COGs: COG4866 conserved hypothetical protein; InterPro IPR016732; KEGG: bth:BT_3689 hypothetical protein; SPTR: uncharacterized protein; PFAM: Uncharacterized conserved protein (DUF2156) YP_004159977.1 COGs: COG0810 Periplasmic protein TonB links inner and outer membranes; InterPro IPR006260: IPR003538; KEGG: bth:BT_3673 TonB; PFAM: TonB domain; SPTR: uncharacterized protein; TIGRFAM: TonB family protein; PFAM: Gram-negative bacterial tonB protein; TIGRFAM: TonB family C-terminal domain; TC 2.C.1.1.1 YP_004159978.1 COGs: COG4552 acetyltransferase involved in intracellular survival and related acetyltransferase; InterPro IPR000182; KEGG: bth:BT_3688 acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: uncharacterized protein YP_004159979.1 COGs: COG0312 Zn-dependent protease and their inactivated homologs; InterPro IPR002510; KEGG: bth:BT_3649 modulator of DNA gyrase; PFAM: peptidase U62 modulator of DNA gyrase; SPTR: uncharacterized protein; PFAM: modulator of DNA gyrase YP_004159980.1 COGs: COG0312 Zn-dependent protease and their inactivated homologs; InterPro IPR006311: IPR002510; KEGG: bth:BT_3648 modulator of DNA gyrase; PFAM: peptidase U62 modulator of DNA gyrase; SPTR: uncharacterized protein; PFAM: modulator of DNA gyrase YP_004159981.1 COGs: COG1624 conserved hypothetical protein; InterPro IPR014046: IPR003390; KEGG: bfs:BF0397 transmembrane protein; PFAM: protein of unknown function DUF147; SPTR: uncharacterized protein; PFAM: DisA bacterial checkpoint controller nucleotide-binding; TIGRFAM: conserved hypothetical protein TIGR00159 YP_004159982.1 COGs: COG0294 Dihydropteroate synthase; InterPro IPR006390: IPR000489; KEGG: bfs:BF0396 dihydropteroate synthase; PFAM: dihydropteroate synthase DHPS; PRIAM: Dihydropteroate synthase; SPTR: uncharacterized protein; TIGRFAM: dihydropteroate synthase; PFAM: Pterin binding enzyme; TIGRFAM: dihydropteroate synthase YP_004159983.1 COGs: COG0642 Signal transduction histidine kinase; InterProIPR019734: IPR003661: IPR003594: IPR004358: IPR 005467: IPR013026; KEGG: bth:BT_3645 two-component system sensor histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; Tetratricopeptide repeat; SPTR: uncharacterized protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain YP_004159984.1 COGs: COG0770 UDP-N-acetylmuramyl pentapeptide synthase; InterPro IPR005863: IPR000713: IPR013221: IPR004101; KEGG: bfr:BF0451 UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate- D-alanyl-D -alanyl ligase; PFAM: Mur ligase middle domain protein; cytoplasmic peptidoglycan synthetase domain protein; SPTR:UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-al anineligase; TIGRFAM:UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-d iaminopimelate/D-alanyl-D-alanylligase; PFAM: Mur ligase, glutamate ligase domain; Mur ligase, catalytic domain; Mur ligase middle domain; TIGRFAM: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase YP_004159985.1 KEGG: bfr:BF0450 hypothetical protein; SPTR: uncharacterized protein; manually curated; PFAM: VanZ like family YP_004159986.1 COGs: COG0733 Na+-dependent transporter of the SNF family; InterPro IPR000175; KEGG: bfs:BF0389 sodium-dependent transporter; PFAM: sodium:neurotransmitter symporter; SPTR: Transporter; PFAM: Sodium:neurotransmitter symporter family YP_004159987.1 InterPro IPR007781; KEGG: bfs:BF0603 alpha-N-acetylglucosaminidase; PFAM: alpha-N-acetylglucosaminidase; PRIAM: alpha-N-acetylglucosaminidase; SPTR: uncharacterized protein; PFAM: alpha-N-acetylglucosaminidase (NAGLU) YP_004159988.1 KEGG: bvu:BVU_2201 hypothetical protein; SPTR: uncharacterized protein YP_004159989.1 KEGG: bth:BT_3098 hypothetical protein; SPTR: uncharacterized protein YP_004159990.1 KEGG: bth:BT_3098 hypothetical protein; SPTR: uncharacterized protein YP_004159991.1 KEGG: bvu:BVU_2200 hypothetical protein; SPTR: uncharacterized protein YP_004159992.1 KEGG: mar:MAE_23900 hypothetical protein; SPTR: Predicted protein YP_004159993.1 COGs: COG1136 ABC-type antimicrobial peptide transport system ATPase component; InterPro IPR017871: IPR003593: IPR003439: IPR015854; KEGG: bfs:BF0387 ABC transporter ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: uncharacterized protein; PFAM: ABC transporter YP_004159994.1 InterPro IPR012910: IPR000531; KEGG: pru:PRU_1888 TonB dependent receptor; PFAM: TonB-dependent receptor plug; TonB-dependent receptor; SPTR: uncharacterized protein; PFAM: TonB dependent receptor; TonB-dependent Receptor Plug Domain YP_004159995.1 InterPro IPR012944; KEGG: pru:PRU_1889 hypothetical protein; PFAM: RagB/SusD domain protein; SPTR: uncharacterized protein; PFAM: SusD family YP_004159996.1 COGs: COG1179 Dinucleotide-utilizing protein involved in molybdopterin and thiamine biosynthesis family 1; InterPro IPR000594; KEGG: bfs:BF0386 ThiF family protein; PFAM: UBA/THIF-type NAD/FAD binding protein; SPTR: uncharacterized protein; PFAM: ThiF family YP_004159997.1 COGs: COG0475 Kef-type K+ transport systems membrane components; InterPro IPR006153: IPR006016; KEGG: bfs:BF0385 Na+/H+ antiporter; PFAM: sodium/hydrogen exchanger; UspA domain-containing protein; SPTR: uncharacterized protein; PFAM: Sodium/hydrogen exchanger family; TC 2.A.37 YP_004159998.1 COGs: COG0136 Aspartate-semialdehyde dehydrogenase; InterProIPR005986: IPR012080: IPR000319: IPR000534: IPR 012280; KEGG: bfs:BF0384 aspartate-semialdehyde dehydrogenase; PFAM: Semialdehyde dehydrogenase dimerisation region; Semialdehyde dehydrogenase NAD - binding; PRIAM: Aspartate-semialdehyde dehydrogenase; SPTR: Aspartate-semialdehyde dehydrogenase; TIGRFAM: aspartate-semialdehyde dehydrogenase; PFAM: Semialdehyde dehydrogenase, dimerisation domain; Semialdehyde dehydrogenase, NAD binding domain; TIGRFAM: aspartate-semialdehyde dehydrogenase, gamma-proteobacterial; aspartate-semialdehyde dehydrogenase (peptidoglycan organisms) YP_004159999.1 InterPro IPR012944; KEGG: phe:Phep_4138 RagB/SusD domain protein; PFAM: RagB/SusD domain protein; SPTR: uncharacterized protein; PFAM: SusD family YP_004160000.1 InterPro IPR012910: IPR000531; KEGG: bfs:BF0381 hypothetical protein; PFAM: TonB-dependent receptor plug; TonB-dependent receptor; SPTR: uncharacterized protein; PFAM: TonB dependent receptor; TonB-dependent Receptor Plug Domain YP_004160001.1 COGs: COG2971 N-acetylglucosamine kinase; KEGG: bfs:BF0382 hypothetical protein; SPTR: uncharacterized protein; PFAM: BadF/BadG/BcrA/BcrD ATPase YP_004160002.1 InterPro IPR012910: IPR000531; KEGG: bfr:BF0440 hypothetical protein; PFAM: TonB-dependent receptor plug; TonB-dependent receptor; SPTR: uncharacterized protein; PFAM: TonB dependent receptor; TonB-dependent Receptor Plug Domain YP_004160003.1 InterPro IPR012944; KEGG: bfs:BF0380 lipoprotein; PFAM: RagB/SusD domain protein; SPTR: uncharacterized protein; PFAM: SusD family YP_004160005.1 COGs: COG3876 conserved hypothetical protein; InterPro IPR008302; KEGG: bfs:BF0379 hypothetical protein; PFAM: Uncharacterised conserved protein UCP016719; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF1343) YP_004160006.1 COGs: COG0591 Na+/proline symporter; InterPro IPR001734; KEGG: bfr:BF0437 sodium/iodide co-transporter; PFAM: Na+/solute symporter; SPTR: uncharacterized protein; PFAM: Sodium:solute symporter family YP_004160007.1 COGs: COG1520 FOG: WD40-like repeat; InterPro IPR018391: IPR003961: IPR004843: IPR002372; KEGG: bfr:BF0436 xanthan lyase; PFAM: metallophosphoesterase; Fibronectin type III domain protein; Pyrrolo-quinoline quinone repeat-containing protein; SMART: Pyrrolo-quinoline quinone beta-propeller repeat; SPTR: uncharacterized protein; PFAM: Calcineurin-like phosphoesterase; PQQ enzyme repeat YP_004160008.1 COGs: COG0463 glycosyltransferase involved in cell wall biogenesis; InterPro IPR001173; KEGG: bfr:BF0434 glycosyltransferase; PFAM: glycosyl transferase 2; SPTR: uncharacterized protein; PFAM: glycosyl transferase 2 YP_004160009.1 COGs: COG2385 Sporulation protein and related protein; InterPro IPR013486: IPR013693; KEGG: pru:PRU_1563 group 2 family glycosyltransferase; PFAM: Stage II sporulation protein D; SPTR: glycosyltransferase; TIGRFAM: SpoIID/LytB domain protein; PFAM: Stage II sporulation protein; TIGRFAM: SpoIID/LytB domain YP_004160010.1 KEGG: bfs:BF0372 transmembrane permease; SPTR: uncharacterized protein; PFAM: Major Facilitator Superfamily YP_004160011.1 COGs: COG3876 conserved hypothetical protein; InterPro IPR008302; KEGG: bfr:BF0430 hypothetical protein; PFAM: Uncharacterised conserved protein UCP016719; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF1343) YP_004160012.1 COGs: COG0277 FAD/FMN-containing dehydrogenase; InterPro IPR017896: IPR016166: IPR006094: IPR004113; KEGG: bfs:BF0370 FAD-binding oxidoreductase; PFAM: FAD linked oxidase domain protein; SPTR: uncharacterized protein; PFAM: FAD binding domain; FAD linked oxidases, C-terminal domain YP_004160013.1 COGs: COG4299 conserved hypothetical protein; KEGG: bfs:BF0369 transmembrane protein; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF1624); GWT1 YP_004160014.1 COGs: COG2971 N-acetylglucosamine kinase; KEGG: bfr:BF0427 hypothetical protein; SPTR: uncharacterized protein; PFAM: BadF/BadG/BcrA/BcrD ATPase YP_004160015.1 COGs: COG2103 sugar phosphate isomerase; InterPro IPR005486: IPR005488: IPR001347; KEGG: bfs:BF0367 N-acetylmuramic acid-6-phosphate etherase; PFAM: sugar isomerase (SIS); SPTR: N-acetylmuramic acid 6-phosphate etherase; PFAM: SIS domain; TIGRFAM: N-acetylmuramic acid 6-phosphate etherase YP_004160016.1 COGs: COG1680 Beta-lactamase class C and other penicillin binding protein; InterPro IPR001466: IPR001087; KEGG: bfs:BF0366 beta-lactamase/acylhydrolase; PFAM: beta-lactamase; lipolytic protein G-D-S-L family; SPTR: uncharacterized protein; PFAM: GDSL-like Lipase/Acylhydrolase; Beta-lactamase YP_004160017.1 COGs: COG0545 FKBP-type peptidyl-prolyl cis-trans isomerase 1; InterPro IPR001179; KEGG: bth:BT_3612 FKBP-type peptidyl-prolyl cis-trans isomerase FkpA; PFAM: peptidylprolyl isomerase FKBP-type; SPTR: peptidyl-prolyl cis-trans isomerase; PFAM: FKBP-type peptidyl-prolyl cis-trans isomerase YP_004160018.1 COGs: COG0423 glycyl-tRNA synthetase (class II); InterPro IPR002315: IPR006195: IPR002314: IPR004154; KEGG: bvu:BVU_0207 glycyl-tRNA synthetase; PFAM: tRNA synthetase class II (G H P and S); Anticodon-binding domain protein; SPTR: glycyl-tRNA synthetase; TIGRFAM: glycyl-tRNA synthetase; PFAM: Anticodon binding domain; tRNA synthetase class II core domain (G, H, P, S and T); TIGRFAM: glycyl-tRNA synthetase, dimeric type YP_004160019.1 COGs: COG1874 Beta-galactosidase; InterPro IPR019801: IPR001944; KEGG: bfs:BF3793 exported beta-galactosidase; PFAM: glycoside hydrolase 35; PRIAM: Beta-galactosidase; SPTR: Beta-galactosidase; PFAM: glycosyl hydrolases family 35 YP_004160020.1 KEGG: pru:PRU_2116 hypothetical protein; SPTR: uncharacterized protein YP_004160021.1 KEGG: bvu:BVU_4157 cell surface protein; SPTR: uncharacterized protein YP_004160022.1 COGs: COG3943 Virulence protein; InterPro IPR011204; KEGG: amt:Amet_3301 hypothetical protein; SPTR: uncharacterized protein YP_004160023.1 COGs: COG0188 type IIA topoisomerase (DNA gyrase/topo II topoisomerase IV) A subunit; InterPro IPR002205; KEGG: bth:BT_3579 DNA topoisomerase IV subunit A; PFAM: DNA gyrase/topoisomerase IV subunit A; PRIAM: DNA topoisomerase (ATP-hydrolyzing); SMART: DNA gyrase/topoisomerase IV subunit A; SPTR: uncharacterized protein; PFAM: DNA gyrase/topoisomerase IV, subunit A YP_004160024.1 KEGG: bth:BT_3578 hypothetical protein; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF3316) YP_004160025.1 COGs: COG0793 Periplasmic protease; InterPro IPR005151; KEGG: bfs:BF0351 hypothetical protein; PFAM: peptidase S41; SMART: peptidase S41; SPTR: uncharacterized protein; PFAM: peptidase S41 YP_004160026.1 COGs: COG1629 Outer membrane receptor protein mostly Fe transport; InterPro IPR012910: IPR000531; KEGG: bfs:BF0326 TonB-dependent receptor exported protein; PFAM: TonB-dependent receptor plug; TonB-dependent receptor; SPTR: TonB-dependent receptor YP_004160027.1 COGs: COG3174 membrane protein; KEGG: bfs:BF0325 transmembrane protein; SPTR: uncharacterized protein YP_004160028.1 COGs: COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)protein; InterPro IPR006664: IPR006665; KEGG: bth:BT_1391 hypothetical protein; PFAM: OmpA/MotB domain protein; SPTR: uncharacterized protein; PFAM: OmpA family YP_004160029.1 COGs: COG2954 conserved hypothetical protein; InterPro IPR012042: IPR008172; KEGG: bfs:BF0324 hypothetical protein; PFAM: adenylate cyclase; SPTR: uncharacterized protein; PFAM: CYTH domain YP_004160030.1 KEGG: bfs:BF0322 hypothetical protein; SPTR: uncharacterized protein YP_004160031.1 InterPro IPR010744: IPR019759; KEGG: bth:BT_3196 hypothetical protein; PFAM: CI repressor; peptidase S24/S26A/S26B, conserved region; SPTR: uncharacterized protein; PFAM: peptidase S24-like; Bacteriophage CI repressor helix-turn-helix domain YP_004160032.1 KEGG: ecb:100069533 BTB (POZ) domain containing 12 YP_004160033.1 KEGG: bth:BT_3197 hypothetical protein; SPTR: uncharacterized protein YP_004160034.1 KEGG: bth:BT_3198 hypothetical protein; SPTR: uncharacterized protein YP_004160035.1 KEGG: ppp:PHYPADRAFT_137618 hypothetical protein; SPTR: Predicted protein YP_004160036.1 InterPro IPR005902: IPR017975; KEGG: bth:BT_3199 non-specific DNA-binding protein; SPTR: uncharacterized protein; TIGRFAM: DNA-binding protein; PFAM: Bacterial DNA-binding protein; TIGRFAM: DNA-binding protein, histone-like YP_004160037.1 InterPro IPR018247: IPR006619: IPR002502; KEGG: bth:BT_3200 N-acetylmuramoyl-L-alanine amidase; PFAM: N-acetylmuramoyl-L-alanine amidase 2; SMART: Animal peptidoglycan recognition protein PGRP; N-acetylmuramoyl-L-alanine amidase 2; SPTR: uncharacterized protein; PFAM: N-acetylmuramoyl-L-alanine amidase YP_004160038.1 SPTR: uncharacterized protein YP_004160039.1 KEGG: bfr:BF3850 hypothetical protein; SPTR: uncharacterized protein YP_004160040.1 KEGG: bfr:BF3849 hypothetical protein; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF3575) YP_004160041.1 InterPro IPR014941; KEGG: bfr:BF3848 hypothetical protein; PFAM: protein of unknown function DUF1812; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF1812) YP_004160042.1 KEGG: bfr:BF3847 hypothetical protein; SPTR: uncharacterized protein; manually curated YP_004160043.1 KEGG: bfr:BF3846 hypothetical protein; SPTR: uncharacterized protein YP_004160044.1 KEGG: fsu:Fisuc_0343 hypothetical protein; SPTR: Conserved domain protein YP_004160045.1 InterPro IPR000182; KEGG: bth:BT_2116 hypothetical protein; PFAM: GCN5-related N-acetyltransferase; SPTR: GCN5-related N-acetyltransferase-like protein; PFAM: Acetyltransferase (GNAT) family YP_004160046.1 KEGG: bfr:BF3845 hypothetical protein; SPTR: uncharacterized protein YP_004160047.1 COGs: COG3093 Plasmid maintenance system antidote protein; InterPro IPR013430: IPR001387; KEGG: pru:PRU_0963 virulence-associated protein; PFAM: hypothetical protein; SMART: hypothetical protein; SPTR: Toxin-antitoxin system, antitoxin component, Xre family; TIGRFAM: addiction module antidote protein, HigA family; PFAM: Helix-turn-helix; TIGRFAM: addiction module antidote protein, HigA family YP_004160048.1 InterPro IPR007711; KEGG: pru:PRU_0962 hypothetical protein; PFAM: plasmid maintenance system killer; SPTR: uncharacterized protein; PFAM: Plasmid maintenance system killer protein YP_004160049.1 KEGG: fsu:Fisuc_1583 hypothetical protein; SPTR: uncharacterized protein YP_004160050.1 InterPro IPR000182; KEGG: bth:BT_2116 hypothetical protein; PFAM: GCN5-related N-acetyltransferase; SPTR: GCN5-related N-acetyltransferase-like protein YP_004160051.1 COGs: COG3943 Virulence protein; KEGG: bth:BT_p548233 DNA-binding protein; SPTR: Toxin-antitoxin system, toxin component, Fic family YP_004160052.1 InterPro IPR013230; KEGG: bfr:BF3841 hypothetical protein; PFAM: peptidase M15A; SPTR: uncharacterized protein; PFAM: peptidase M15 YP_004160053.1 KEGG: fsu:Fisuc_1964 hypothetical protein; SPTR: Conserved domain protein YP_004160054.1 InterPro IPR000182; KEGG: bfr:BF3837 hypothetical protein; PFAM: GCN5-related N-acetyltransferase; SPTR: uncharacterized protein YP_004160055.1 COGs: COG1186 Protein chain release factor B; InterPro IPR000352: IPR005139; KEGG: bvu:BVU_1485 peptide chain release factor RF-2; PFAM: Class I peptide chain release factor; PCRF domain protein; SPTR: uncharacterized protein; PFAM: PCRF domain; RF-1 domain; TIGRFAM: peptide chain release factor 2 YP_004160056.1 COGs: COG1649 conserved hypothetical protein; InterPro IPR003790; KEGG: pdi:BDI_3432 hypothetical protein; PFAM: protein of unknown function DUF187; SPTR: uncharacterized protein; PFAM: Uncharacterised BCR, COG1649 YP_004160057.1 KEGG: dfe:Dfer_1233 hypothetical protein; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF1624) YP_004160058.1 SPTR: uncharacterized protein YP_004160059.1 COGs: COG1472 Beta-glucosidase-related glycosidase; InterPro IPR017975: IPR001764: IPR002772; KEGG: pru:PRU_1812 glucan 1,4-beta-glucosidase; PFAM: glycoside hydrolase 3; SPTR: Thermostable beta-glucosidase B (Gentiobiase)(Cellobiase) (Beta-D-glucoside glucohydrolase); PFAM: glycosyl hydrolase 3 C terminal domain; glycosyl hydrolase 3 N terminal domain YP_004160060.1 KEGG: fjo:Fjoh_4558 hypothetical protein; SPTR: uncharacterized protein YP_004160061.1 COGs: COG1629 Outer membrane receptor protein mostly Fe transport; InterPro IPR012910: IPR000531; KEGG: bfr:BF4329 hypothetical protein; PFAM: TonB-dependent receptor plug; TonB-dependent receptor; SPTR: uncharacterized protein; PFAM: TonB-dependent Receptor Plug Domain; TonB dependent receptor YP_004160062.1 COGs: COG0612 Zn-dependent peptidase; InterPro IPR011765: IPR007863; KEGG: bth:BT_3551 zinc protease; PFAM: peptidase M16; SPTR: uncharacterized protein; PFAM: peptidase M16 inactive domain; Insulinase (peptidase M16) YP_004160063.1 COGs: COG1022 Long-chain acyl-CoA synthetase (AMP-forming); InterPro IPR020845: IPR000873; KEGG: bfs:BF0320 AMP binding long chain acyl-CoA synthetase; PFAM: AMP-dependent synthetase and ligase; SPTR: uncharacterized protein; PFAM: AMP-binding enzyme YP_004160064.1 KEGG: fjo:Fjoh_1188 hypothetical protein; SPTR: uncharacterized protein YP_004160065.1 KEGG: cbk:CLL_A2172 cell surface protein; SPTR: Cell surface protein YP_004160066.1 COGs: COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylase; InterPro IPR001261: IPR002933: IPR011650; KEGG: bth:BT_3549 acetylornithine deacetylase; PFAM: peptidase M20; peptidase dimerisation domain protein; SPTR: uncharacterized protein; PFAM: peptidase M20/M25/M40; peptidase dimerisation domain YP_004160067.1 InterPro IPR012910: IPR000531; KEGG: pdi:BDI_2076 hypothetical protein; PFAM: TonB-dependent receptor plug; TonB-dependent receptor; SPTR: outer membrane protein probably involved in nutrient binding; PFAM: TonB dependent receptor; TonB-dependent Receptor Plug Domain YP_004160068.1 InterPro IPR012944; KEGG: pdi:BDI_2077 hypothetical protein; PFAM: RagB/SusD domain protein; SPTR: outer membrane protein probably involved in nutrient binding; PFAM: SusD family YP_004160069.1 COGs: COG3119 Arylsulfatase A; InterPro IPR000917; KEGG: bvu:BVU_1266 exported sulfatase; PFAM: sulfatase; SPTR: exported sulfatase; PFAM: Sulfatase YP_004160070.1 COGs: COG0642 Signal transduction histidine kinase; InterProIPR003594: IPR001789: IPR018060: IPR004358: IPR 005467: IPR011110: IPR011123: IPR003661: IPR000005; KEGG: bvu:BVU_1267 two-component system sensor histidine kinase/response regulator, hybrid; PFAM: ATP-binding region ATPase domain protein; two component regulator three Y domain-containing protein; two component regulator propeller; histidine kinase A domain protein; response regulator receiver; helix-turn-helix- domain containing protein AraC type; SMART: response regulator receiver; ATP-binding region ATPase domain protein; Helix-turn-helix, AraC domain; SPTR: two-component system sensor histidine kinase/response regulator; PFAM: Y_Y_Y domain; two component regulator propeller; Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; Bacterial regulatory helix-turn-helix proteins, AraC family YP_004160071.1 COGs: COG4942 Membrane-bound metallopeptidase; InterPro IPR016047; KEGG: bth:BT_3464 peptidase; PFAM: peptidase M23; SPTR: uncharacterized protein; PFAM: peptidase M23 YP_004160072.1 KEGG: bfs:BF0274 lipoprotein; SPTR: uncharacterized protein YP_004160073.1 InterPro IPR019734: IPR013026: IPR001440; KEGG: bth:BT_3462 TPR domain-containing protein; PFAM: hypothetical protein; SPTR: uncharacterized protein YP_004160074.1 COGs: COG0756 dUTPase; InterPro IPR008181: IPR008180; KEGG: bfs:BF0272 deoxyuridine 5'-triphosphate nucleotidohydrolase; PFAM: deoxyUTP pyrophosphatase; PRIAM: dUTP diphosphatase; SPTR: Deoxyuridine 5'-triphosphate nucleotidohydrolase; TIGRFAM: deoxyuridine 5'-triphosphate nucleotidohydrolase Dut; PFAM: dUTPase; TIGRFAM: deoxyuridine 5'-triphosphate nucleotidohydrolase (dut) YP_004160075.1 COGs: COG0232 dGTP triphosphohydrolase; InterPro IPR006261: IPR003607: IPR006674; KEGG: bfs:BF0271 deoxyguanosinetriphosphate triphosphohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; PRIAM: dGTPase; SMART: metal-dependent phosphohydrolase HD region; SPTR: uncharacterized protein; TIGRFAM: deoxyguanosinetriphosphate triphosphohydrolase; PFAM: HD domain; TIGRFAM: deoxyguanosinetriphosphate triphosphohydrolase YP_004160076.1 KEGG: bfs:BF0270 hemolysin A; SPTR: uncharacterized protein YP_004160077.1 COGs: COG3176 hemolysin; KEGG: bfr:BF0321 hypothetical protein; SPTR: uncharacterized protein; manually curated YP_004160078.1 COGs: COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog; InterPro IPR014284: IPR007627: IPR013249; KEGG: bth:BT_1197 RNA polymerase ECF-type sigma factor; PFAM: Sigma-70 region 4 type 2; sigma-70 region 2 domain protein; SPTR: uncharacterized protein; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family YP_004160079.1 COGs: COG3669 alpha-L-fucosidase; InterPro IPR000933: IPR000421; KEGG: bvu:BVU_0535 alpha-L-fucosidase; PFAM: coagulation factor 5/8 type domain protein; PRIAM: alpha-L-fucosidase; SMART: glycoside hydrolase 29 (alpha-L-fucosidase); SPTR: uncharacterized protein; PFAM: F5/8 type C domain; alpha-L-fucosidase YP_004160080.1 COGs: COG3250 Beta-galactosidase/beta-glucuronidase; InterProIPR006101: IPR006104: IPR006102: IPR006103: IPR 004199; KEGG: bvu:BVU_0536 beta-glycosidase; PFAM: glycoside hydrolase 2; glycoside hydrolase 2 sugar binding; glycoside hydrolase 2 immunoglobulin domain protein beta-sandwich; glycoside hydrolase 42 domain 5 loop region; SPTR: uncharacterized protein; PFAM: domain; glycosyl hydrolases family 2, TIM barrel domain; Beta galactosidase small chain; glycosyl hydrolases family 2, sugar binding domain YP_004160081.1 COGs: COG3525 N-acetyl-beta-hexosaminidase; InterPro IPR001540: IPR015883; KEGG: bvu:BVU_0537 beta-N-acetylhexosaminidase; PFAM: glycoside hydrolase 20; PRIAM: Beta-N-acetylhexosaminidase; SPTR: uncharacterized protein; PFAM: glycosyl hydrolase 20, catalytic domain YP_004160082.1 COGs: COG3119 Arylsulfatase A; InterPro IPR000917: IPR001202; KEGG: bvu:BVU_0538 sulfatase; PFAM: sulfatase; SPTR: uncharacterized protein; PFAM: Sulfatase YP_004160083.1 InterPro IPR012944; KEGG: bvu:BVU_0539 hypothetical protein; PFAM: RagB/SusD domain protein; SPTR: uncharacterized protein; PFAM: SusD family YP_004160084.1 InterPro IPR018247: IPR012910: IPR000531; KEGG: bvu:BVU_0540 hypothetical protein; PFAM: TonB-dependent receptor plug; TonB-dependent receptor; SPTR: uncharacterized protein; PFAM: TonB dependent receptor; TonB-dependent Receptor Plug Domain YP_004160085.1 COGs: COG0642 Signal transduction histidine kinase; InterProIPR018062: IPR003661: IPR003594: IPR001789: IPR 018060: IPR004358: IPR005467: IPR011110: IPR011123: IPR000005; KEGG: bvu:BVU_0542 two-component system sensor histidine kinase/response regulator, hybrid; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; two component regulator three Y domain-containing protein; two component regulator propeller; helix-turn-helix- domain containing protein AraC type; SMART: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; Helix-turn-helix, AraC domain; SPTR: uncharacterized protein; PFAM: Y_Y_Y domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; two component regulator propeller; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; Bacterial regulatory helix-turn-helix proteins, AraC family YP_004160086.1 COGs: COG2001 conserved hypothetical protein; InterPro IPR003444: IPR020603; KEGG: bth:BT_3456 cell division protein MraZ; PFAM: MraZ domain; SPTR: Protein mraZ; PFAM: MraZ protein; TIGRFAM: mraZ protein YP_004160087.1 COGs: COG0275 S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis; InterPro IPR002903; KEGG: bfr:BF0313 S-adenosyl-methyltransferase MraW; PFAM: methyltransferase; SPTR: Ribosomal RNA small subunit methyltransferase H; TIGRFAM: S-adenosyl-methyltransferase MraW; PFAM: MraW methylase; TIGRFAM: S-adenosyl-methyltransferase MraW YP_004160088.1 KEGG: bth:BT_3454 hypothetical protein; SPTR: uncharacterized protein YP_004160089.1 COGs: COG0768 Cell division protein FtsI/penicillin-binding protein 2; InterPro IPR005543: IPR005311: IPR001460; KEGG: bfr:BF0311 penicillin-binding protein; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; PASTA domain containing protein; PRIAM: peptidoglycan glycosyltransferase; SMART: PASTA domain containing protein; SPTR: uncharacterized protein; PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding Protein dimerisation domain; PASTA domain YP_004160090.1 COGs: COG0769 UDP-N-acetylmuramyl tripeptide synthase; InterPro IPR005761: IPR000713: IPR013221: IPR004101; KEGG: bth:BT_3452 UDP-N-acetylmuramoylalanyl-D-glutamate--2,6- diaminopimelate ligase; PFAM: Mur ligase middle domain protein; cytoplasmic peptidoglycan synthetase domain protein; SPTR: uncharacterized protein; TIGRFAM: UDP-N-acetylmuramyl-tripeptide synthetase; PFAM: Mur ligase, glutamate ligase domain; Mur ligase, catalytic domain; Mur ligase middle domain; TIGRFAM: UDP-N-acetylmuramyl-tripeptide synthetase YP_004160091.1 COGs: COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase; InterPro IPR003524: IPR018480: IPR018481; KEGG: bfs:BF0257 phospho-N-acetylmuramoyl-pentapeptide-transferase; PFAM: glycosyl transferase, family 4, conserved region; phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site; SPTR:phospho-N-acetylmuramoyl-pentapeptide-transfer ase; TIGRFAM:phospho-N-acetylmuramoyl-pentapeptide-trans ferase; PFAM: glycosyl transferase 4; TIGRFAM: phospho-N-acetylmuramoyl-pentapeptide-transferase YP_004160092.1 COGs: COG0771 UDP-N-acetylmuramoylalanine-D-glutamate ligase; InterPro IPR005762: IPR013221: IPR004101; KEGG: bfs:BF0256 UDP-N-acetylmuramoylalanine--D-glutamate ligase; PFAM: Mur ligase middle domain protein; cytoplasmic peptidoglycan synthetase domain protein; SPTR: UDP-N-acetylmuramoylalanine--D-glutamate ligase; TIGRFAM: UDP-N-acetylmuramoylalanine/D-glutamate ligase; PFAM: Mur ligase, glutamate ligase domain; Mur ligase middle domain; TIGRFAM: UDP-N-acetylmuramoylalanine--D-glutamate ligase YP_004160093.1 COGs: COG0772 Bacterial cell division membrane protein; InterPro IPR001182; KEGG: bfs:BF0255 transmembrane rod-shape determining protein; PFAM: cell cycle protein; SPTR: uncharacterized protein; PFAM: Cell cycle protein YP_004160094.1 COGs: COG0707 UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase; InterPro IPR006009: IPR004276: IPR007235; KEGG: bfs:BF0254 UDPdiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; PFAM: glycosyltransferase 28 domain; glycosyl transferase 28; PRIAM: UDPdiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; SPTR: UDPdiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; TIGRFAM:UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; PFAM: glycosyltransferase 28 N-terminal domain; glycosyltransferase 28 C-terminal domain; TIGRFAM: UDPdiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase YP_004160095.1 COGs: COG0773 UDP-N-acetylmuramate-alanine ligase; InterPro IPR005758: IPR000713: IPR013221: IPR004101; KEGG: bth:BT_3447 UDP-N-acetylmuramate--L-alanine ligase; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; SPTR: UDP-N-acetylmuramate--L-alanine ligase; TIGRFAM: UDP-N-acetylmuramate/alanine ligase; PFAM: Mur ligase, glutamate ligase domain; Mur ligase, catalytic domain; Mur ligase middle domain; TIGRFAM: UDP-N-acetylmuramate--alanine ligase YP_004160096.1 KEGG: bth:BT_3446 cell division protein FtsQ; SPTR: uncharacterized protein YP_004160097.1 COGs: COG0849 Actin-like ATPase involved in cell division; InterPro IPR020823: IPR003494; KEGG: bfs:BF0251 cell division protein; PFAM: cell division protein FtsA; SPTR: uncharacterized protein; TIGRFAM: cell division protein FtsA; PFAM: Cell division protein FtsA; TIGRFAM: cell division protein FtsA YP_004160098.1 COGs: COG0206 Cell division GTPase; InterPro IPR000158: IPR020805: IPR003008: IPR018316; KEGG: bfs:BF0250 cell division protein FtsZ; PFAM: Tubulin/FtsZ GTPase; Tubulin/FtsZ, 2-layer sandwich domain; SPTR: Cell division protein ftsZ; TIGRFAM: cell division protein FtsZ; PFAM: Tubulin/FtsZ family, GTPase domain; FtsZ family, C-terminal domain; TIGRFAM: cell division protein FtsZ YP_004160099.1 COGs: COG1610 conserved hypothetical protein; InterPro IPR019004; KEGG: bfs:BF0249 hypothetical protein; SPTR: uncharacterized protein; PFAM: Yqey-like protein YP_004160100.1 COGs: COG1381 Recombinational DNA repair protein (RecF pathway); InterPro IPR003717; KEGG: bth:BT_3431 DNA repair protein; PFAM: Recombination protein O RecO; SPTR: DNA repair protein RecO; TIGRFAM: DNA repair protein RecO; PFAM: Recombination protein O C terminal; Recombination protein O N terminal; TIGRFAM: DNA repair protein RecO YP_004160101.1 InterPro IPR002583; KEGG: bth:BT_3430 30S ribosomal protein S20; PFAM: ribosomal protein S20; SPTR: 30S ribosomal protein S20; TIGRFAM: ribosomal protein S20; PFAM: Ribosomal protein S20; TIGRFAM: ribosomal protein S20 YP_004160102.1 COGs: COG0187 type IIA topoisomerase (DNA gyrase/topo II topoisomerase IV) B subunit; InterProIPR011557: IPR018522: IPR003594: IPR001241: IPR 000565: IPR013506: IPR006171: IPR002288; KEGG: bvu:BVU_1388 DNA gyrase B subunit; PFAM: DNA topoisomerase type IIA subunit B region 2 domain protein; ATP-binding region ATPase domain protein; TOPRIM domain-containing protein; DNA gyrase subunit B domain protein; PRIAM: DNA topoisomerase (ATP-hydrolyzing); SMART: DNA topoisomerase II; ATP-binding region ATPase domain protein; SPTR: DNA gyrase subunit B; TIGRFAM: DNA gyrase, B subunit; PFAM: Toprim domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; DNA gyrase B; DNA gyrase B subunit, carboxyl terminus; TIGRFAM: DNA gyrase, B subunit YP_004160103.1 KEGG: bth:BT_3427 hypothetical protein; SPTR: uncharacterized protein; manually curated; PFAM: Protein of unknown function (DUF3109) YP_004160104.1 KEGG: bvu:BVU_3214 hypothetical protein; SPTR: uncharacterized protein YP_004160105.1 COGs: COG0696 phosphoglyceromutase; InterPro IPR005995: IPR011258: IPR006124; KEGG: bvu:BVU_1375 phosphoglyceromutase; PFAM: BPG-independent PGAM domain protein; metalloenzyme domain protein; PRIAM: phosphoglycerate mutase; SPTR: 2,3-bisphosphoglycerate-independent phosphoglycerate mutase; TIGRFAM: phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent; PFAM: Metalloenzyme superfamily; BPG-independent PGAM N-terminus (iPGM_N); TIGRFAM: 2,3-bisphosphoglycerate-independent phosphoglycerate mutase YP_004160106.1 COGs: COG0598 Mg2+ and Co2+ transporter; InterPro IPR002523; KEGG: bfs:BF0240 cationic transporter; PFAM: Mg2 transporter protein CorA family protein; SPTR: uncharacterized protein; PFAM: CorA-like Mg2+ transporter protein YP_004160107.1 COGs: COG0164 Ribonuclease HII; InterPro IPR001352; KEGG: bth:BT_3412 ribonuclease HII; PFAM: ribonuclease HII/HIII; PRIAM: Ribonuclease H; SPTR: Ribonuclease; PFAM: Ribonuclease HII YP_004160108.1 InterPro IPR019734: IPR013026: IPR001440: IPR000792; KEGG: bvu:BVU_1370 hypothetical protein; PFAM: hypothetical protein; regulatory protein LuxR; SMART: Tetratricopeptide repeat; SPTR: uncharacterized protein YP_004160109.1 InterPro IPR012910: IPR000531; KEGG: bvu:BVU_1369 hypothetical protein; PFAM: TonB-dependent receptor plug; TonB-dependent receptor; SPTR: TonB-dependent outer membrane receptor; PFAM: TonB-dependent Receptor Plug Domain; TonB dependent receptor YP_004160110.1 InterPro IPR012944; KEGG: bvu:BVU_1368 hypothetical protein; PFAM: RagB/SusD domain protein; SPTR: outer membrane protein, probably involved in nutrient binding; PFAM: SusD family YP_004160111.1 KEGG: bvu:BVU_1367 hypothetical protein; SPTR: uncharacterized protein; PFAM: Membrane protein of unknown function (DUF340) YP_004160112.1 COGs: COG2431 membrane protein; InterPro IPR005642; KEGG: bvu:BVU_1366 hypothetical protein; PFAM: protein of unknown function DUF340 membrane; SPTR: uncharacterized protein; PFAM: Membrane protein of unknown function (DUF340) YP_004160113.1 COGs: COG3250 Beta-galactosidase/beta-glucuronidase; InterProIPR006101: IPR006104: IPR006102: IPR006103: IPR 004199; KEGG: bvu:BVU_1365 glycoside hydrolase; PFAM: glycoside hydrolase 2; glycoside hydrolase 2 sugar binding; glycoside hydrolase 2 immunoglobulin domain protein beta-sandwich; glycoside hydrolase 42 domain 5 loop region; SPTR: uncharacterized protein; PFAM: domain; glycosyl hydrolases family 2, TIM barrel domain; glycosyl hydrolases family 2, sugar binding domain; Beta galactosidase small chain YP_004160114.1 COGs: COG3408 glycogen debranching protein; InterPro IPR001661; KEGG: bvu:BVU_1364 glycoside hydrolase; PFAM: glycoside hydrolase 37; SPTR: uncharacterized protein; PFAM: Trehalase; Mannosyl oligosaccharide glucosidase YP_004160115.1 COGs: COG3808 Inorganic pyrophosphatase; InterPro IPR004131: IPR006162; KEGG: bfr:BF0289 membrane-bound proton-translocating pyrophosphatase; PFAM: Inorganic H pyrophosphatase; PRIAM: Inorganic diphosphatase; SPTR: uncharacterized protein; TIGRFAM: V-type H(+)-translocating pyrophosphatase; PFAM: Inorganic H+ pyrophosphatase; TIGRFAM: vacuolar-type H(+)-translocating pyrophosphatase YP_004160116.1 COGs: COG0393 conserved hypothetical protein; InterPro IPR002765; KEGG: bfs:BF0226 hypothetical protein; PFAM: protein of unknown function DUF74; SPTR: uncharacterized protein; PFAM: Domain of unknown function (DUF74) YP_004160117.1 COGs: COG3669 alpha-L-fucosidase; InterPro IPR016286: IPR000933; KEGG: bfs:BF0810 alpha-L-fucosidase; PFAM: glycoside hydrolase 29 (alpha-L-fucosidase); PRIAM: alpha-L-fucosidase; SMART: glycoside hydrolase 29 (alpha-L-fucosidase); SPTR: alpha-L-fucosidase; PFAM: alpha-L-fucosidase YP_004160118.1 KEGG: bfs:BF1924 hypothetical protein; SPTR: uncharacterized protein; PFAM: Domain of unknown function (DUF1083) YP_004160119.1 KEGG: dfe:Dfer_1007 hypothetical protein; SPTR: uncharacterized protein YP_004160120.1 COGs: COG1629 Outer membrane receptor protein mostly Fe transport; InterPro IPR012910: IPR000531; KEGG: bvu:BVU_0563 hypothetical protein; PFAM: TonB-dependent receptor plug; TonB-dependent receptor; SPTR: TonB-dependent receptor plug domain protein; PFAM: TonB-dependent Receptor Plug Domain; TonB dependent receptor YP_004160121.1 KEGG: bfs:BF0569 anti-sigma factor; SPTR: anti-sigma factor YP_004160122.1 COGs: COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog; InterPro IPR014284: IPR014327: IPR007627: IPR013249; KEGG: bfs:BF0568 RNA polymerase ECF-type sigma factor; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; SPTR: RNA polymerase ECF-type sigma factor; TIGRFAM: RNA polymerase sigma-70 factor; RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; RNA polymerase sigma-70 factor, Bacteroides expansion family 1 YP_004160123.1 COGs: COG0520 Selenocysteine lyase; InterPro IPR010970: IPR000192; KEGG: bth:BT_3409 aminotransferase, cysteine desulfurase; PFAM: aminotransferase class V; SPTR: uncharacterized protein; TIGRFAM: cysteine desulfurase, SufS subfamily; PFAM: Aminotransferase class-V; TIGRFAM: cysteine desulfurases, SufS subfamily YP_004160124.1 COGs: COG0719 ABC-type transport system involved in Fe-S cluster assembly permease component; InterPro IPR011542: IPR000825; KEGG: bth:BT_3408 ABC transporter permease; PFAM: SufBD protein; SPTR: uncharacterized protein; TIGRFAM: FeS assembly protein SufD; PFAM: Uncharacterized protein family (UPF0051); TIGRFAM: FeS assembly protein SufD, group 1 YP_004160125.1 COGs: COG0396 ABC-type transport system involved in Fe-S cluster assembly ATPase component; InterPro IPR010230: IPR003439; KEGG: bvu:BVU_1358 ABC transporter ATP-binding protein; PFAM: ABC transporter related; SPTR: uncharacterized protein; TIGRFAM: FeS assembly ATPase SufC; PFAM: ABC transporter; TIGRFAM: FeS assembly ATPase SufC YP_004160126.1 COGs: COG0719 ABC-type transport system involved in Fe-S cluster assembly permease component; InterPro IPR010231: IPR000825; KEGG: bfs:BF0221 cysteine desulfurase activator complex subunit SufB; PFAM: SufBD protein; SPTR: FeS assembly protein SufB; TIGRFAM: FeS assembly protein SufB; PFAM: Uncharacterized protein family (UPF0051); TIGRFAM: FeS assembly protein SufB YP_004160127.1 InterPro IPR003825; KEGG: bth:BT_3405 hypothetical protein; PFAM: Colicin V production protein; SPTR: CvpA family protein; PFAM: Colicin V production protein YP_004160129.1 COGs: COG0532 Translation initiation factor 2 (IF-2; GTPase); InterProIPR000178: IPR005225: IPR006847: IPR000795: IPR 004161; KEGG: bth:BT_3404 translation initiation factor IF-2; PFAM: protein synthesis factor GTP-binding; translation initiation factor IF-2 domain-containing protein; elongation factor Tu domain 2 protein; SPTR: Translation initiation factor IF-2; TIGRFAM: translation initiation factor IF-2; small GTP-binding protein; PFAM: Elongation factor Tu domain 2; Translation-initiation factor 2; Translation initiation factor IF-2, N-terminal region; Elongation factor Tu GTP binding domain; TIGRFAM: small GTP-binding protein domain; translation initiation factor IF-2 YP_004160130.1 COGs: COG0195 Transcription elongation factor; InterPro IPR010213: IPR013735; KEGG: bfs:BF0218 transcription elongation factor NusA; PFAM: NusA domain-containing protein; SPTR: uncharacterized protein; TIGRFAM: transcription termination factor NusA; PFAM: NusA N-terminal domain; TIGRFAM: transcription termination factor NusA YP_004160131.1 InterPro IPR020790: IPR003728; KEGG: bfs:BF0217 hypothetical protein; PFAM: protein of unknown function DUF150; SPTR: Ribosome maturation factor rimP; PFAM: Uncharacterised BCR, YhbC family COG0779 YP_004160132.1 COGs: COG3506 conserved hypothetical protein; InterPro IPR015987: IPR009784; KEGG: pdi:BDI_2253 hypothetical protein; PFAM: protein of unknown function DUF1349; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF1349) YP_004160133.1 COGs: COG1472 Beta-glucosidase-related glycosidase; InterPro IPR001764: IPR002772; KEGG: pru:PRU_2590 family 3 glycosyl hydrolase; PFAM: glycoside hydrolase 3; SPTR: uncharacterized protein; PFAM: glycosyl hydrolase 3 C terminal domain; glycosyl hydrolase 3 N terminal domain YP_004160134.1 COGs: COG2382 Enterochelin esterase; InterPro IPR004193: IPR000801; KEGG: pdi:BDI_2687 glycosylhydrolase; PFAM: esterase; glycoside hydrolase 13 domain protein; SPTR: uncharacterized protein; PFAM: esterase YP_004160135.1 KEGG: bfr:BF0247 hypothetical protein; SPTR: uncharacterized protein YP_004160136.1 COGs: COG1451 metal-dependent hydrolase; InterPro IPR002725; KEGG: bfs:BF0203 hypothetical protein; PFAM: protein of unknown function DUF45; SPTR: uncharacterized protein; PFAM: Protein of unknown function DUF45 YP_004160137.1 KEGG: bfs:BF0201 lipoprotein; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF2807) YP_004160138.1 KEGG: bth:BT_3397 hypothetical protein; SPTR: uncharacterized protein YP_004160139.1 COGs: COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog; InterPro IPR014284: IPR007627: IPR013249; KEGG: bfs:BF0198 extracytoplasmic function alternative sigma factor; PFAM: Sigma-70 region 4 type 2; sigma-70 region 2 domain protein; SPTR: uncharacterized protein; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family YP_004160140.1 COGs: COG0548 Acetylglutamate kinase; InterPro IPR004662: IPR011148: IPR001048; KEGG: bth:BT_3395 acetylglutamate kinase; PFAM: aspartate/glutamate/uridylate kinase; SPTR: Acetylglutamate kinase; TIGRFAM: acetylglutamate kinase; PFAM: Amino acid kinase; TIGRFAM: acetylglutamate kinase YP_004160141.1 COGs: COG1166 Arginine decarboxylase (spermidine biosynthesis); InterPro IPR002985: IPR000183; KEGG: bvu:BVU_1337 arginine decarboxylase; PFAM: Orn/DAP/Arg decarboxylase 2; SPTR: Arginine decarboxylase; TIGRFAM: arginine decarboxylase; PFAM: Pyridoxal-dependent decarboxylase, C-terminal sheet domain; Pyridoxal-dependent decarboxylase, pyridoxal binding domain; TIGRFAM: arginine decarboxylase, biosynthetic YP_004160142.1 COGs: COG0703 Shikimate kinase; InterPro IPR000623; KEGG: bth:BT_3393 shikimate kinase; PFAM: shikimate kinase; PRIAM: Shikimate kinase; SPTR: Shikimate kinase; PFAM: Shikimate kinase YP_004160143.1 COGs: COG3560 oxidoreductase related to nitroreductase; InterPro IPR000415; KEGG: bfs:BF0191 hypothetical protein; PFAM: nitroreductase; SPTR: uncharacterized protein; PFAM: Nitroreductase YP_004160144.1 InterPro IPR012944; KEGG: coc:Coch_1140 RagB/SusD domain protein; PFAM: RagB/SusD domain protein; SPTR: lipoprotein; PFAM: SusD family YP_004160145.1 COGs: COG4771 Outer membrane receptor for ferrienterochelin and colicins; InterPro IPR012910: IPR000531; KEGG: bfs:BF0807 outer membrane protein; PFAM: TonB-dependent receptor plug; TonB-dependent receptor; SPTR: TonB-dependent receptor plug domain protein; PFAM: TonB dependent receptor; TonB-dependent Receptor Plug Domain YP_004160146.1 COGs: COG3341 double-stranded RNA/RNA-DNA hybrid binding protein; KEGG: bth:BT_3391 ribonuclease H-related protein; SPTR: Ribonuclease H; PFAM: RNase H; Caulimovirus viroplasmin YP_004160147.1 COGs: COG1132 ABC-type multidrug transport system ATPase and permease components; InterProIPR017871: IPR003593: IPR003439: IPR017940: IPR 001140; KEGG: bth:BT_3386 ABC transporter, ATP-binding protein; PFAM: ABC transporter related; ABC transporter transmembrane region; SMART: AAA ATPase; SPTR: uncharacterized protein; PFAM: ABC transporter transmembrane region; ABC transporter YP_004160148.1 COGs: COG1132 ABC-type multidrug transport system ATPase and permease components; InterProIPR017871: IPR003593: IPR003439: IPR017940: IPR 001140; KEGG: bvu:BVU_1072 ABC transporter ATP-binding protein; PFAM: ABC transporter related; ABC transporter transmembrane region; SMART: AAA ATPase; SPTR: ABC transporter ATP-binding protein; manually curated; PFAM: ABC transporter transmembrane region; ABC transporter YP_004160149.1 KEGG: bvu:BVU_1073 glycosyl transferase; SPTR: glycosyltransferase 4 YP_004160150.1 InterPro IPR002052: IPR001173; KEGG: bvu:BVU_1071 glycosyl transferase; PFAM: glycosyl transferase 2; SPTR: glycosyltransferase, group 2 family protein; PFAM: glycosyl transferase 2 YP_004160151.1 KEGG: pdi:BDI_2820 hypothetical protein; SPTR: uncharacterized protein YP_004160152.1 COGs: COG1368 phosphoglycerol transferase and related protein alkaline phosphatase superfamily; InterPro IPR012160: IPR000917; KEGG: bth:BT_0873 sulfatase; PFAM: sulfatase; SPTR: Membrane protein; PFAM: Sulfatase YP_004160153.1 KEGG: pdi:BDI_2811 hypothetical protein; SPTR: glycoside transferase, family 2; PFAM: Protein of unknown function (DUF2029) YP_004160154.1 COGs: COG0438 glycosyltransferase; InterPro IPR001296; KEGG: pdi:BDI_2815 mannosyltransferase; PFAM: glycosyl transferase group 1; SPTR: uncharacterized protein; PFAM: glycosyl transferases group 1 YP_004160155.1 COGs: COG0463 glycosyltransferase involved in cell wall biogenesis; InterPro IPR001173; KEGG: tye:THEYE_A2095 lipopolysaccharide biosynthesis glycosyltransferase; PFAM: glycosyl transferase 2; SPTR: Beta 1,4 glucosyltransferase; PFAM: glycosyl transferase 2 YP_004160156.1 KEGG: aap:NT05HA_2255 capsular polysaccharide synthesis protein; SPTR: Capsular polysaccharide synthesis protein; PFAM: Capsular polysaccharide synthesis protein YP_004160157.1 COGs: COG1216 glycosyltransferase; InterPro IPR001173; KEGG: dfe:Dfer_1547 glycosyl transferase 2; PFAM: glycosyl transferase 2; SPTR: Lipooligosaccharide biosynthesis glycosyltransferase; PFAM: glycosyl transferase 2 YP_004160158.1 KEGG: similar to Galactoside 2-alpha-L-fucosyltransferase 3 (GDP-L-fucose:beta-D-galactoside 2-alpha-L-fucosyltransferase 3) (Alpha(1,2)FT 3) (Fucosyltransferase 10) (Secretory blood group protein 1); SPTR: uncharacterized protein; PFAM: glycosyl transferase 11 YP_004160159.1 COGs: COG0463 glycosyltransferase involved in cell wall biogenesis; InterPro IPR001173; KEGG: ter:Tery_3238 glycosyl transferase; PFAM: glycosyl transferase 2; SPTR: glycosyltransferase 1; PFAM: glycosyl transferase 2 YP_004160160.1 COGs: COG1560 Lauroyl/myristoyl acyltransferase; InterPro IPR004960; KEGG: pru:PRU_2910 lipid A biosynthesis acyltransferase; PFAM: lipid A biosynthesis acyltransferase; SPTR: Lipid A biosynthesis acyltransferase; PFAM: Bacterial lipid A biosynthesis acyltransferase YP_004160161.1 COGs: COG0859 ADP-heptose:LPS heptosyltransferase; InterPro IPR002201; KEGG: bth:BT_3362 heptosyltransferase; PFAM: glycosyl transferase 9; SPTR: uncharacterized protein; PFAM: glycosyltransferase 9 (heptosyltransferase) YP_004160162.1 COGs: COG0111 phosphoglycerate dehydrogenase and related dehydrogenase; InterPro IPR020921: IPR006139: IPR006140; KEGG: bfr:BF0222 erythronate-4-phosphate dehydrogenase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; SPTR: Erythronate-4-phosphate dehydrogenase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; Domain of unknown function (DUF3410); D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain YP_004160163.1 COGs: COG0299 Folate-dependent phosphoribosylglycinamide formyltransferase PurN; InterPro IPR004607: IPR001555: IPR002376; KEGG: bfs:BF0180 phosphoribosylglycinamide formyltransferase; PFAM: formyl transferase domain protein; SPTR: uncharacterized protein; TIGRFAM: phosphoribosylglycinamide formyltransferase; PFAM: formyl transferase; TIGRFAM: phosphoribosylglycinamide formyltransferase, formyltetrahydrofolate-dependent YP_004160164.1 COGs: COG0236 ACP; InterPro IPR003231: IPR006162: IPR009081: IPR006163; KEGG: bth:BT_3359 ACP; PFAM: phosphopantetheine-binding; SPTR: ACP; TIGRFAM: ACP; PFAM: phosphopantetheine attachment site; TIGRFAM: ACP YP_004160165.1 COGs: COG0304 3-oxoacyl-ACP synthase; InterPro IPR017568: IPR018201: IPR014030: IPR014031; KEGG: bfs:BF0178 3-oxoacyl-[acyl-carrier-protein] synthase II; PFAM: Beta-ketoacyl synthase; SPTR: 3-oxoacyl-[acyl-carrier-protein] synthase 2; TIGRFAM: 3-oxoacyl-[acyl-carrier-protein] synthase 2; PFAM: Beta-ketoacyl synthase, N-terminal domain; Beta-ketoacyl synthase, C-terminal domain; TIGRFAM: beta-ketoacyl-acyl-carrier-protein synthase II YP_004160166.1 COGs: COG0571 dsRNA-specific ribonuclease; InterPro IPR011907: IPR000999: IPR001159; KEGG: bth:BT_3357 ribonuclease III; PFAM: ribonuclease III; double-stranded RNA binding domain protein; PRIAM: Ribonuclease III; SMART: ribonuclease III; double-stranded RNA binding domain protein; SPTR: uncharacterized protein; TIGRFAM: ribonuclease III; PFAM: RNase3 domain; Double-stranded RNA binding motif; TIGRFAM: ribonuclease III, bacterial YP_004160167.1 COGs: COG0205 6-phosphofructokinase; InterPro IPR012003: IPR000023; KEGG: bfs:BF0176 6-phosphofructokinase; PFAM: phosphofructokinase; SPTR: uncharacterized protein; PFAM: phosphofructokinase; TIGRFAM: phosphofructokinase YP_004160168.1 InterPro IPR004993; KEGG: bth:BT_3355 auxin-regulated protein; PFAM: GH3 auxin-responsive promoter; SPTR: uncharacterized protein; PFAM: GH3 auxin-responsive promoter YP_004160169.1 COGs: COG0482 tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase contains the PP-loop ATPase domain; InterPro IPR004506; KEGG: bfr:BF0215 tRNA-specific 2-thiouridylase MnmA; SPTR: tRNA methyl transferase; TIGRFAM: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; PFAM: tRNA methyl transferase; TIGRFAM: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase YP_004160170.1 COGs: COG0561 hydrolase of the HAD superfamily; InterPro IPR000150: IPR006379: IPR001757: IPR013200; KEGG: bfs:BF0163 haloacid dehalogenase-like hydrolase; PFAM: Haloacid dehalogenase domain protein hydrolase type 3; SPTR: uncharacterized protein; TIGRFAM: Cof-like hydrolase; HAD-superfamily hydrolase, subfamily IIB; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily; HAD-superfamily hydrolase, subfamily IIB YP_004160171.1 KEGG: bfs:BF3240 lipoprotein; SPTR: uncharacterized protein YP_004160172.1 KEGG: tps:THAPSDRAFT_25593 hypothetical protein; SPTR: Predicted protein YP_004160173.1 COGs: COG0215 Cysteinyl-tRNA synthetase; InterPro IPR002308: IPR015803: IPR015273; KEGG: bfr:BF0196 cysteinyl-tRNA synthetase; PFAM: Cysteinyl-tRNA synthetase class Ia; Cysteinyl-tRNA synthetase class Ia DALR; PRIAM: Cysteine--tRNA ligase; SPTR: uncharacterized protein; TIGRFAM: cysteinyl-tRNA synthetase; PFAM: tRNA synthetases class I (C) catalytic domain; DALR domain; TIGRFAM: cysteinyl-tRNA synthetase YP_004160174.1 COGs: COG3119 Arylsulfatase A; InterPro IPR000917; KEGG: bth:BT_3349 sulfatase YidJ; PFAM: sulfatase; SPTR: uncharacterized protein; PFAM: Sulfatase YP_004160175.1 InterPro IPR019454: IPR010905; KEGG: bth:BT_3348 unsaturated glucuronyl hydrolase; PFAM: glycosyl hydrolase 88; Cell-wall binding lipoprotein YkyA, SPTR: uncharacterized protein; PFAM: glycosyl Hydrolase 88 YP_004160176.1 KEGG: bfs:BF0158 hypothetical protein; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF3108) YP_004160177.1 COGs: COG0845 Membrane-fusion protein; InterPro IPR006143; KEGG: bth:BT_3339 AcrA/AcrE family multidrug resistance protein; PFAM: hemolysin D; SPTR: uncharacterized protein; TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: HlyD family secretion protein; TIGRFAM: RND family efflux transporter, MFP subunit YP_004160178.1 COGs: COG0841 Cation/multidrug efflux pump; InterPro IPR004764: IPR001036; KEGG: bth:BT_3338 AcrB/AcrD family multidrug resistance protein; PFAM: acriflavin resistance protein; SPTR: uncharacterized protein; TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: AcrB/AcrD/AcrF family; TIGRFAM: The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family YP_004160179.1 COGs: COG1538 Outer membrane protein; InterPro IPR010131: IPR003423; KEGG: bth:BT_3337 outer membrane protein OprM precursor, multidrug resistance protein; PFAM: outer membrane efflux protein; SPTR: uncharacterized protein; TIGRFAM: RND efflux system, outer membrane lipoprotein, NodT family; PFAM: Outer membrane efflux protein; TIGRFAM: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family YP_004160180.1 COGs: COG1043 Acyl-(ACP); InterPro IPR010137: IPR001451; KEGG: bth:BT_3336 UDP-N-acetylglucosamine acyltransferase; PFAM: transferase hexapeptide repeat containing protein; PRIAM:Acyl-[acyl-carrier-protein]--UDP-N-acetylgluc osamineO-acyltransferase; SPTR:Acyl-[acyl-carrier-protein]-UDP-N-acetylglucos amineO-acyltransferase; TIGRFAM:acyl-[acyl-carrier-protein]--UDP-N-acetylgl ucosamineO-acyltransferase; PFAM: Bacterial transferase hexapeptide (three repeats); TIGRFAM: acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase YP_004160181.1 COGs: COG0174 Glutamine synthetase; InterPro IPR008147: IPR008146; KEGG: bth:BT_0785 glutamine synthetase I; PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp; SPTR: Glutamate--ammonia ligase; PFAM: Glutamine synthetase, catalytic domain; Glutamine synthetase, beta-Grasp domain YP_004160182.1 KEGG: bfs:BF0152 hypothetical protein; SPTR: uncharacterized protein YP_004160183.1 InterPro IPR002575; KEGG: bfs:BF0850 desulfatase; PFAM: aminoglycoside phosphotransferase; SPTR: uncharacterized protein; PFAM: phosphotransferase enzyme family YP_004160184.1 KEGG: vfm:VFMJ11_B0085 hypothetical protein; SPTR: uncharacterized protein YP_004160185.1 COGs: COG0642 Signal transduction histidine kinase; InterProIPR003661: IPR003594: IPR001789: IPR018060: IPR 004358: IPR005467: IPR011110: IPR011123: IPR000005; KEGG: bth:BT_3334 two-component system sensor histidine kinase/response regulator, hybrid ('one-component system'); PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; two component regulator three Y domain-containing protein; two component regulator propeller; response regulator receiver; helix-turn-helix- domain containing protein AraC type; SMART: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; Helix-turn-helix, AraC domain; SPTR: uncharacterized protein; PFAM: Y_Y_Y domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; two component regulator propeller; His Kinase A (phosphoacceptor) domain; Bacterial regulatory helix-turn-helix proteins, AraC family YP_004160186.1 COGs: COG3119 Arylsulfatase A; InterPro IPR000917; KEGG: bth:BT_3333 arylsulfatase A precursor (ASA); PFAM: sulfatase; SPTR: uncharacterized protein; PFAM: Sulfatase YP_004160187.1 COGs: COG1629 Outer membrane receptor protein mostly Fe transport; InterPro IPR012910: IPR000531; KEGG: sli:Slin_0106 TonB-dependent receptor plug; PFAM: TonB-dependent receptor plug; TonB-dependent receptor; SPTR: uncharacterized protein; manually curated; PFAM: TonB dependent receptor; TonB-dependent Receptor Plug Domain YP_004160188.1 InterPro IPR012944; KEGG: sli:Slin_3951 RagB/SusD domain protein; PFAM: RagB/SusD domain protein; SPTR: uncharacterized protein; PFAM: SusD family YP_004160189.1 InterPro IPR012910: IPR000531; KEGG: bth:BT_3332 hypothetical protein; PFAM: TonB-dependent receptor plug; TonB-dependent receptor; SPTR: SusC homolog; PFAM: TonB dependent receptor; TonB-dependent Receptor Plug Domain YP_004160190.1 InterPro IPR012944; KEGG: bth:BT_3331 hypothetical protein; PFAM: RagB/SusD domain protein; SPTR: SusD homolog; PFAM: SusD family YP_004160191.1 InterPro IPR019775; KEGG: bth:BT_3330 hypothetical protein; SPTR: uncharacterized protein YP_004160192.1 InterPro IPR012970: IPR003159: IPR004103; KEGG: bth:BT_2964 chondroitinase AC precursor; PFAM: polysaccharide lyase 8 domain protein; polysaccharide lyase 8; polysaccharide lyase 8 alpha-helical; PRIAM: Chondroitin AC lyase; SPTR: Chondroitinase AC; PFAM: polysaccharide lyase 8, N terminal alpha-helical domain; polysaccharide lyase 8, super-sandwich domain; polysaccharide lyase 8, C-terminal beta-sandwich domain YP_004160193.1 COGs: COG0042 tRNA-dihydrouridine synthase; InterPro IPR001269; KEGG: bth:BT_3326 dihydrouridine synthase; PFAM: dihydrouridine synthase DuS; SPTR: uncharacterized protein; PFAM: Dihydrouridine synthase (Dus) YP_004160194.1 InterPro IPR015176: IPR015177: IPR003159; KEGG: bth:BT_3324 chondroitinase (chondroitin lyase) precursor; PFAM: Lyase catalytic; Lyase; polysaccharide lyase 8; SPTR: uncharacterized protein; PFAM: Lyase, N terminal; Lyase, catalytic; polysaccharide lyase 8, super-sandwich domain; polysaccharide lyase 8, C-terminal beta-sandwich domain YP_004160195.1 KEGG: bfs:BF0149 hypothetical protein; SPTR: uncharacterized protein YP_004160196.1 KEGG: bfs:BF0148 hypothetical protein; SPTR: uncharacterized protein; manually curated; PFAM: Protein of unknown function (DUF2851) YP_004160197.1 COGs: COG0289 Dihydrodipicolinate reductase; InterPro IPR011770: IPR000846; KEGG: bth:BT_3320 dihydrodipicolinate reductase; PFAM: dihydrodipicolinate reductase; PRIAM: Dihydrodipicolinate reductase; SPTR: Dihydrodipicolinate reductase; TIGRFAM: dihydrodipicolinate reductase; PFAM: Dihydrodipicolinate reductase, N-terminus; Dihydrodipicolinate reductase, C-terminus; TIGRFAM: dihydrodipicolinate reductase YP_004160198.1 InterPro IPR000223: IPR019758: IPR019759; KEGG: bth:BT_3319 signal peptidase I; PFAM: peptidase S24/S26A/S26B, conserved region; SPTR: uncharacterized protein; TIGRFAM: signal peptidase I; PFAM: peptidase S26; peptidase S24-like; TIGRFAM: signal peptidase I, bacterial type YP_004160199.1 InterPro IPR000223: IPR019759; KEGG: bfs:BF0145 exported signal peptidase I; PFAM: peptidase S24/S26A/S26B, conserved region; SPTR: uncharacterized protein; TIGRFAM: signal peptidase I; PFAM: peptidase S24-like; TIGRFAM: signal peptidase I, bacterial type YP_004160200.1 InterPro IPR014985; KEGG: bth:BT_3317 hypothetical protein; PFAM: WbqC-like family protein; SPTR: uncharacterized protein; PFAM: WbqC-like protein family YP_004160201.1 COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661: IPR003594: IPR004358: IPR005467; KEGG: bth:BT_3645 two-component system sensor histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: uncharacterized protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain YP_004160202.1 COGs: COG0642 Signal transduction histidine kinase; InterProIPR003661: IPR003594: IPR004358: IPR005467: IPR 011716; KEGG: bth:BT_3645 two-component system sensor histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; Tetratricopeptide TPR_3 repeat-containing protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: uncharacterized protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain YP_004160203.1 COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661: IPR003594: IPR004358: IPR005467; KEGG: bth:BT_3645 two-component system sensor histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: uncharacterized protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain YP_004160204.1 COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661: IPR003594: IPR004358: IPR005467; KEGG: bfr:BF0456 two-component system sensor histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: uncharacterized protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain YP_004160205.1 InterPro IPR011123; KEGG: phe:Phep_3632 two component regulator three Y domain protein; PFAM: two component regulator three Y domain-containing protein; SPTR: uncharacterized protein YP_004160206.1 InterPro IPR012910: IPR000531; KEGG: zpr:ZPR_0907 TonB-dependent receptor Plug domain protein; PFAM: TonB-dependent receptor plug; TonB-dependent receptor; SPTR: uncharacterized protein; PFAM: TonB dependent receptor; TonB-dependent Receptor Plug Domain YP_004160207.1 InterPro IPR012944; KEGG: zpr:ZPR_0908 hypothetical protein; PFAM: RagB/SusD domain protein; SPTR: uncharacterized protein; PFAM: SusD family YP_004160208.1 InterPro IPR011123: IPR000792; KEGG: phe:Phep_3632 two component regulator three Y domain protein; PFAM: two component regulator three Y domain-containing protein; regulatory protein LuxR; SPTR: uncharacterized protein YP_004160209.1 COGs: COG1629 Outer membrane receptor protein mostly Fe transport; InterPro IPR012910: IPR000531; KEGG: phe:Phep_2722 TonB-dependent receptor plug; PFAM: TonB-dependent receptor plug; TonB-dependent receptor; SPTR: uncharacterized protein; PFAM: TonB dependent receptor; TonB-dependent Receptor Plug Domain YP_004160210.1 InterPro IPR012944; KEGG: sli:Slin_2453 RagB/SusD domain protein; PFAM: RagB/SusD domain protein; SPTR: uncharacterized protein; PFAM: SusD family YP_004160211.1 KEGG: ooe:OEOE_1431 trypsin-like serine protease; SPTR: uncharacterized protein YP_004160212.1 COGs: COG3250 Beta-galactosidase/beta-glucuronidase; InterPro IPR006101: IPR006104: IPR006103; KEGG: bvu:BVU_1785 beta-glycosidase; PFAM: glycoside hydrolase 2 sugar binding; glycoside hydrolase 2; PRIAM: Beta-galactosidase; SPTR: glycoside hydrolase 2 protein; PFAM: domain; glycosyl hydrolases family 2, TIM barrel domain; Di-glucose binding within endoplasmic reticulum; glycosyl hydrolases family 2, sugar binding domain YP_004160213.1 InterPro IPR010905; KEGG: phe:Phep_2694 glycosyl hydrolase 88; PFAM: glycosyl hydrolase 88; SPTR: uncharacterized protein; PFAM: glycosyl Hydrolase 88 YP_004160214.1 COGs: COG3250 Beta-galactosidase/beta-glucuronidase; InterPro IPR006101: IPR006104: IPR006103; KEGG: phe:Phep_2700 beta-galactosidase; PFAM: glycoside hydrolase 2; glycoside hydrolase 2 sugar binding; SPTR: uncharacterized protein; PFAM: domain; glycosyl hydrolases family 2, TIM barrel domain; glycosyl hydrolases family 2, sugar binding domain YP_004160215.1 COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR020904: IPR002347: IPR002198; KEGG: bfs:BF0143 D-mannonate oxidoreductase; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: D-mannonate oxidoreductase; PFAM: short chain dehydrogenase YP_004160216.1 COGs: COG1312 D-mannonate dehydratase; InterPro IPR004628; KEGG: bfs:BF0142 mannonate dehydratase; PFAM: Mannonate dehydratase; PRIAM: Mannonate dehydratase; SPTR: uncharacterized protein; TIGRFAM: mannonate dehydratase; PFAM: D-mannonate dehydratase (UxuA); TIGRFAM: mannonate dehydratase YP_004160217.1 KEGG: pru:PRU_2215 hypothetical protein; SPTR: uncharacterized protein YP_004160218.1 InterPro IPR011659; KEGG: pdi:BDI_3581 hypothetical protein; SPTR: uncharacterized protein; PFAM: WD40-like Beta Propeller Repeat YP_004160219.1 COGs: COG0580 glycerol uptake facilitator and related permease (Major Intrinsic Protein Family); InterPro IPR000425: IPR005797: IPR012269; KEGG: pru:PRU_2051 aquaporin Z; PFAM: major intrinsic protein; Cytochrome b/b6 domain; SPTR: uncharacterized protein; TIGRFAM: MIP family channel protein; PFAM: Major intrinsic protein; TIGRFAM: MIP family channel proteins YP_004160220.1 COGs: COG1472 Beta-glucosidase-related glycosidase; InterPro IPR001764: IPR002772: IPR018486: IPR019800; KEGG: bth:BT_3314 thermostable beta-glucosidase B; PFAM: glycoside hydrolase 3; SPTR: uncharacterized protein; PFAM: glycosyl hydrolase 3 C terminal domain; glycosyl hydrolase 3 N terminal domain YP_004160221.1 COGs: COG2730 Endoglucanase; InterPro IPR001547: IPR018087; KEGG: aca:ACP_0988 glycosyl hydrolase, family 5; PFAM: glycoside hydrolase 5; SPTR: uncharacterized protein; PFAM: Cellulase (glycosyl hydrolase 5) YP_004160222.1 COGs: COG5520 O-glycosyl hydrolase; InterPro IPR001139; KEGG: pdi:BDI_1787 beta-glycosidase; PFAM: glycoside hydrolase 30; PRIAM: glucan endo-1,6-beta-glucosidase; SPTR: uncharacterized protein; PFAM: O-glycosyl hydrolase 30 YP_004160223.1 KEGG: bth:BT_3309 transcriptional regulator; SPTR: Transcriptional regulator YP_004160224.1 COGs: COG1636 conserved hypothetical protein; InterPro IPR003828; KEGG: bvu:BVU_2425 hypothetical protein; PFAM: protein of unknown function DUF208; SPTR: uncharacterized protein; PFAM: Uncharacterized BCR, COG1636 YP_004160225.1 COGs: COG0612 Zn-dependent peptidase; InterPro IPR011765: IPR007863: IPR001431; KEGG: bfr:BF0174 zinc protease YmxG; PFAM: peptidase M16; SPTR: uncharacterized protein; PFAM: peptidase M16 inactive domain; Insulinase (peptidase M16) YP_004160226.1 COGs: COG0794 sugar phosphate isomerase involved in capsule formation; InterPro IPR001347; KEGG: bfs:BF0137 SIS-domain-containing protein; PFAM: sugar isomerase (SIS); PRIAM: Arabinose-5-phosphate isomerase; SPTR: uncharacterized protein; PFAM: SIS domain; TIGRFAM: KpsF/GutQ family protein YP_004160227.1 COGs: COG0524 Sugar kinase ribokinase; InterPro IPR011611: IPR002173; KEGG: bfs:BF0136 fructokinase; PFAM: PfkB domain protein; SPTR: uncharacterized protein; PFAM: pfkB family carbohydrate kinase YP_004160228.1 COGs: COG2365 Protein tyrosine/serine phosphatase; InterPro IPR004861: IPR016130: IPR000387; KEGG: bfs:BF0135 hypothetical protein; PFAM: tyrosine phosphatase; SPTR: uncharacterized protein; PFAM: Tyrosine phosphatase YP_004160229.1 COGs: COG0513 Superfamily II DNA and RNA helicase; InterProIPR011545: IPR001650: IPR005580: IPR000629: IPR 014021: IPR014014: IPR014001; KEGG: bfs:BF0134 RNA helicase dead-box protein; PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; DbpA RNA-binding domain protein; SMART: DEAD-like helicase; helicase domain protein; SPTR: uncharacterized protein; PFAM: Helicase conserved C-terminal domain; DbpA RNA binding domain; DEAD/DEAH box helicase YP_004160230.1 COGs: COG0783 DNA-binding ferritin-like protein (oxidative damage protectant); InterPro IPR002177: IPR008331; KEGG: pdi:BDI_0620 non-specific DNA-binding protein Dps; PFAM: Ferritin Dps family protein; SPTR: uncharacterized protein; PFAM: Ferritin-like domain YP_004160231.1 COGs: COG0583 Transcriptional regulator; InterPro IPR000847: IPR005119; KEGG: bfs:BF1318 redox-sensitive transcriptional activator; PFAM: LysR substrate-binding; regulatory protein LysR; SPTR: uncharacterized protein; PFAM: LysR substrate binding domain; Bacterial regulatory helix-turn-helix protein, lysR family YP_004160232.1 COGs: COG0450 Peroxiredoxin; InterPro IPR000866: IPR019479: IPR017559: IPR017936; KEGG: bfs:BF1210 alkyl hydroperoxide reductase C subunit; PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Peroxiredoxin-like; SPTR: Alkyl hydroperoxide reductase subunit C; TIGRFAM: peroxiredoxin; PFAM: C-terminal domain of 1-Cys peroxiredoxin; AhpC/TSA family; TIGRFAM: peroxiredoxin YP_004160233.1 COGs: COG3634 Alkyl hydroperoxide reductase large subunit; InterPro IPR000103: IPR013027: IPR012081: IPR008255; KEGG: pdi:BDI_3397 alkyl hydroperoxide reductase subunit F; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: uncharacterized protein; TIGRFAM: alkyl hydroperoxide reductase, F subunit; PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: alkyl hydroperoxide reductase, F subunit YP_004160234.1 InterPro IPR019500; KEGG: bfs:BF0131 hypothetical protein; PFAM: peptidase S46; SPTR: uncharacterized protein; PFAM: peptidase S46 YP_004160235.1 COGs: COG1808 membrane protein; InterPro IPR005240; KEGG: bfs:BF0130 hypothetical protein; PFAM: protein of unknown function DUF389; SPTR: uncharacterized protein; PFAM: Domain of unknown function (DUF389); TIGRFAM: uncharacterized hydrophobic domain YP_004160236.1 COGs: COG2244 Membrane protein involved in the export of O-antigen and teichoic acid; InterPro IPR002797; KEGG: bvu:BVU_1290 polysaccharide biosynthesis protein; PFAM: polysaccharide biosynthesis protein; SPTR: uncharacterized protein; PFAM: polysaccharide biosynthesis protein YP_004160237.1 COGs: COG2255 Holliday junction resolvasome helicase subunit; InterProIPR008824: IPR003959: IPR008823: IPR004605: IPR 003593; KEGG: bth:BT_3285 Holliday junction DNA helicase RuvB; PFAM: AAA ATPase central domain protein; Holliday junction DNA helicase RuvB domain; SMART: AAA ATPase; SPTR: Holliday junction ATP-dependent DNA helicase ruvB; TIGRFAM: Holliday junction DNA helicase RuvB; PFAM: Holliday junction DNA helicase ruvB C-terminus; Holliday junction DNA helicase ruvB N-terminus; TIGRFAM: Holliday junction DNA helicase, RuvB subunit YP_004160239.1 COGs: COG0790 FOG: TPR repeat SEL1 subfamily; InterPro IPR006597; KEGG: aas:Aasi_0895 hypothetical protein; PFAM: Sel1 domain protein repeat-containing protein; SPTR: uncharacterized protein; PFAM: Sel1 repeat; Gram-negative bacterial tonB protein; TIGRFAM: TonB family C-terminal domain YP_004160240.1 COGs: COG0790 FOG: TPR repeat SEL1 subfamily; InterPro IPR006597; KEGG: lpp:lpp1310 hypothetical protein; PFAM: Sel1 domain protein repeat-containing protein; SMART: Sel1 domain protein repeat-containing protein; SPTR: uncharacterized protein; PFAM: Sel1 repeat; Gram-negative bacterial tonB protein; TIGRFAM: TonB family C-terminal domain YP_004160241.1 KEGG: ptr:742010 Purkinje cell protein 2; SPTR: Purkinje cell protein 2 homolog; manually curated YP_004160242.1 KEGG: ter:Tery_2057 hypothetical protein; SPTR: KWG Leptospira; PFAM: KWG Leptospira YP_004160243.1 InterPro IPR013152; KEGG: vpo:Kpol_1033p19 hypothetical protein; SPTR: uncharacterized protein YP_004160244.1 KEGG: rhi:NGR_c03650 hemolysin-type calcium-binding repeat-like hypothetical protein; SPTR: uncharacterized protein YP_004160245.1 KEGG: bts:Btus_2928 hypothetical protein; SPTR: uncharacterized protein YP_004160246.1 COGs: COG1106 ATPase; KEGG: hau:Haur_3672 hypothetical protein; SPTR: uncharacterized protein; PFAM: RecF/RecN/SMC N terminal domain YP_004160247.1 KEGG: sat:SYN_02410 cytoplasmic protein; SPTR: uncharacterized protein YP_004160248.1 KEGG: sat:SYN_02409 cytoplasmic protein; SPTR: uncharacterized protein YP_004160249.1 COGs: COG0641 Arylsulfatase regulator (Fe-S oxidoreductase); InterPro IPR007197; KEGG: sat:SYN_02408 radical SAM superfamily protein; PFAM: radical SAM protein; SPTR: uncharacterized protein; PFAM: Radical SAM superfamily YP_004160250.1 KEGG: mdo:100010750 hypothetical protein LOC100010750; SPTR: uncharacterized protein YP_004160251.1 COGs: COG5492 Bacterial surface protein containing Ig-like domains; InterPro IPR003343; KEGG: clj:CLJU_c22390 surface/cell-adhesion protein; PFAM: Ig domain protein group 2 domain protein; SMART: Ig domain protein group 2 domain protein; SPTR: uncharacterized protein; PFAM: Bacterial Ig-like domain (group 2) YP_004160252.1 InterPro IPR019775; KEGG: cat:CA2559_00400 hypothetical protein; SPTR: uncharacterized protein YP_004160253.1 COGs: COG4912 DNA alkylation repair protein; InterPro IPR014825; KEGG: bfs:BF0126 hypothetical protein; PFAM: DNA alkylation repair enzyme; SPTR: uncharacterized protein; PFAM: DNA alkylation repair enzyme YP_004160254.1 COGs: COG2234 aminopeptidase; InterPro IPR007484; KEGG: bfs:BF0657 aminopeptidase; PFAM: peptidase M28; SPTR: uncharacterized protein; PFAM: peptidase M28 YP_004160255.1 COGs: COG2715 hypothetical protein required for spore maturation in B.subtilis.; InterPro IPR011642: IPR011415; KEGG: bfs:BF0125 transmembrane spore maturation-like protein; PFAM: nucleoside recognition domain protein; SPTR: uncharacterized protein; PFAM: Nucleoside recognition YP_004160256.1 COGs: COG0319 metal-dependent hydrolase; InterPro IPR002036; KEGG: bth:BT_3283 hypothetical protein; PFAM: protein of unknown function UPF0054; SPTR: metalloprotease BACSTE_02421; PFAM: Uncharacterized protein family UPF0054; TIGRFAM: metalloprotein, YbeY/UPF0054 family YP_004160257.1 COGs: COG2017 Galactose mutarotase; InterPro IPR008183: IPR018052; KEGG: bth:BT_3529 aldose 1-epimerase precursor; PFAM: Aldose 1-epimerase; PRIAM: Aldose 1-epimerase; SPTR: uncharacterized protein; PFAM: Aldose 1-epimerase YP_004160258.1 KEGG: bvu:BVU_2232 hypothetical protein; SPTR: uncharacterized protein YP_004160259.1 COGs: COG3507 Beta-xylosidase; InterPro IPR006710: IPR016840; KEGG: bvu:BVU_2231 glycoside hydrolase; PFAM: glycoside hydrolase 43; SPTR: uncharacterized protein; PFAM: glycosyl hydrolases family 43 YP_004160260.1 COGs: COG3507 Beta-xylosidase; InterPro IPR006710; KEGG: bvu:BVU_2230 glycoside hydrolase; PFAM: glycoside hydrolase 43; SPTR: glycoside hydrolase 43 protein; PFAM: glycosyl hydrolases family 43 YP_004160261.1 InterPro IPR012944; KEGG: bvu:BVU_2228 hypothetical protein; PFAM: RagB/SusD domain protein; SPTR: outer membrane protein, probably involved in nutrient binding; PFAM: SusD family YP_004160262.1 InterPro IPR012910: IPR000531; KEGG: bvu:BVU_2227 hypothetical protein; PFAM: TonB-dependent receptor plug; TonB-dependent receptor; SPTR: uncharacterized protein; PFAM: TonB dependent receptor; TonB-dependent Receptor Plug Domain YP_004160263.1 COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358: IPR011110: IPR011123: IPR003661: IPR 003594: IPR001789: IPR000005: IPR018062: IPR018060: IPR005467; KEGG: bvu:BVU_2226 two-component system sensor histidine kinase/response regulator, hybrid; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; two component regulator three Y domain-containing protein; two component regulator propeller; helix-turn-helix- domain containing protein AraC type; SMART: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; Helix-turn-helix, AraC domain; SPTR: uncharacterized protein; PFAM: Y_Y_Y domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; two component regulator propeller; His Kinase A (phosphoacceptor) domain; Bacterial regulatory helix-turn-helix proteins, AraC family YP_004160264.1 COGs: COG3250 Beta-galactosidase/beta-glucuronidase; InterPro IPR006104: IPR006102; KEGG: bvu:BVU_2224 beta-glycosidase; PFAM: glycoside hydrolase 2 sugar binding; glycoside hydrolase 2 immunoglobulin domain protein beta-sandwich; SPTR: uncharacterized protein; PFAM: domain; glycosyl hydrolases family 2, TIM barrel domain; glycosyl hydrolases family 2, sugar binding domain YP_004160265.1 COGs: COG0445 NAD/FAD-utilizing enzyme apparently involved in cell division; InterPro IPR002218: IPR004416: IPR020595; KEGG: bfr:BF0100 tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; PFAM: glucose-inhibited division protein A; SPTR: tRNA uridine 5-carboxymethylaminomethyl modification enzyme mnmG; TIGRFAM: glucose inhibited division protein A; PFAM: glucose inhibited division protein A; TIGRFAM: glucose-inhibited division protein A YP_004160266.1 COGs: COG0503 Adenine/guanine phosphoribosyltransferase and related PRPP-binding protein; InterPro IPR000836: IPR005764; KEGG: bth:BT_3267 adenine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; SPTR: Adenine phosphoribosyltransferase; TIGRFAM: adenine phosphoribosyltransferase; PFAM: phosphoribosyl transferase domain; TIGRFAM: adenine phosphoribosyltransferase YP_004160267.1 COGs: COG0322 Nuclease subunit of the excinuclease complex; InterPro IPR000305: IPR001162: IPR004791; KEGG: bfs:BF0111 excinuclease ABC subunit C; PFAM: excinuclease ABC subunit C; excinuclease ABC subunit C; SMART: excinuclease ABC subunit C; SPTR: UvrABC system protein C; TIGRFAM: excinuclease ABC, C subunit; PFAM: UvrC Helix-hairpin-helix N-terminal; GIY-YIG catalytic domain; TIGRFAM: excinuclease ABC, C subunit YP_004160268.1 COGs: COG1490 D-Tyr-tRNAtyr deacylase; InterPro IPR003732; KEGG: bth:BT_3265 D-tyrosyl-tRNA(Tyr) deacylase; PFAM: D-tyrosyl-tRNA(Tyr) deacylase; SPTR: D-tyrosyl-tRNA(Tyr) deacylase; TIGRFAM: D-tyrosyl-tRNA(Tyr) deacylase; PFAM: D-Tyr-tRNA(Tyr) deacylase; TIGRFAM: D-tyrosyl-tRNA(Tyr) deacylase YP_004160269.1 InterPro IPR004518: IPR012359; KEGG: bth:BT_3264 hypothetical protein; PFAM: MazG nucleotide pyrophosphohydrolase; SPTR: uncharacterized protein; PFAM: MazG nucleotide pyrophosphohydrolase domain YP_004160270.1 COGs: COG0274 Deoxyribose-phosphate aldolase; InterPro IPR002915: IPR011343; KEGG: bfr:BF0095 deoxyribose-phosphate aldolase; PFAM: deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase; PRIAM: Deoxyribose-phosphate aldolase; SPTR: uncharacterized protein; TIGRFAM: deoxyribose-phosphate aldolase; PFAM: DeoC/LacD family aldolase; TIGRFAM: deoxyribose-phosphate aldolase YP_004160271.1 COGs: COG0142 Geranylgeranyl pyrophosphate synthase; InterPro IPR000092; KEGG: bfs:BF0105 octaprenyl-diphosphate synthase; PFAM: polyprenyl synthetase; SPTR: uncharacterized protein; PFAM: polyprenyl synthetase YP_004160272.1 COGs: COG0749 DNA polymerase I - 3'-5' exonuclease and polymerase domains; InterProIPR002298: IPR020046: IPR020047: IPR002562: IPR 001098: IPR018320: IPR019760: IPR002421: IPR008918; KEGG: bfs:BF0104 DNA polymerase I; PFAM: DNA-directed DNA polymerase; 5'-3' exonuclease, N-terminal resolvase-like domain; 5'-3' exonuclease, SAM-fold domain; 3'-5' exonuclease; SMART: 5'-3' exonuclease; Helix-hairpin-helix domain protein class 2; 3'-5' exonuclease; DNA-directed DNA polymerase; SPTR: uncharacterized protein; TIGRFAM: DNA polymerase I; PFAM: 5'-3' exonuclease, C-terminal SAM fold; 3'-5' exonuclease; 5'-3' exonuclease, N-terminal resolvase-like domain; DNA polymerase A; TIGRFAM: DNA polymerase I YP_004160274.1 KEGG: bfs:BF0103 hypothetical protein; SPTR: uncharacterized protein YP_004160275.1 InterPro IPR006674; KEGG: bth:BT_1563 hypothetical protein; PFAM: metal-dependent phosphohydrolase HD sub domain; SPTR: uncharacterized protein; PFAM: HD domain YP_004160276.1 KEGG: bfs:BF0873 hypothetical protein; SPTR: uncharacterized protein YP_004160277.1 InterPro IPR001611; KEGG: sbi:SORBI_05g018020 hypothetical protein; PFAM: leucine-rich repeat-containing protein; SPTR: uncharacterized protein YP_004160278.1 COGs: COG0249 Mismatch repair ATPase (MutS family); InterPro IPR000432; KEGG: zpr:ZPR_4587 mismatch repair protein MutS-like ATPase; PFAM: DNA mismatch repair protein MutS domain protein; SMART: DNA mismatch repair protein MutS domain protein; SPTR: uncharacterized protein; PFAM: MutS domain V YP_004160279.1 COGs: COG1234 Metal-dependent hydrolase of the beta-lactamase superfamily III; KEGG: dsy:DSY0293 hypothetical protein; SPTR: Metallo-beta-lactamase domain-containing protein; PFAM: Metallo-beta-lactamase superfamily YP_004160280.1 COGs: COG0012 GTPase probable translation factor; InterPro IPR006073: IPR002917: IPR013029: IPR004396; KEGG: bvu:BVU_1205 GTP-dependent nucleic acid-binding protein EngD; PFAM: protein of unknown function DUF933; GTP-binding protein HSR1-related; SPTR: GTP-binding protein YchF; TIGRFAM: GTP-binding protein YchF; PFAM: GTPase of unknown function; Protein of unknown function (DUF933); TIGRFAM: GTP-binding protein YchF YP_004160281.1 KEGG: bth:BT_3170 hypothetical protein; SPTR: uncharacterized protein YP_004160282.1 COGs: COG1893 Ketopantoate reductase; InterPro IPR013332: IPR013752; KEGG: bth:BT_3117 oxidoreductase; PFAM: Ketopantoate reductase ApbA/PanE domain protein; SPTR: 2-dehydropantoate 2-reductase; PFAM: Ketopantoate reductase PanE/ApbA; Ketopantoate reductase PanE/ApbA C terminal; TIGRFAM: 2-dehydropantoate 2-reductase YP_004160283.1 InterPro IPR018873; KEGG: bfs:BF2399 hypothetical protein; PFAM: KilA-N, DNA-binding domain; SPTR: uncharacterized protein; PFAM: ORF6N domain YP_004160284.1 COGs: COG1011 hydrolase (HAD superfamily); InterPro IPR005834: IPR006402; KEGG: pru:PRU_0967 HAD-superfamily hydrolase; PFAM: Haloacid dehalogenase domain protein hydrolase; SPTR: uncharacterized protein; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED YP_004160285.1 COGs: COG0682 Prolipoprotein diacylglyceryltransferase; InterPro IPR001640; KEGG: bfs:BF4367 prolipoprotein diacylglyceryl transferase; PFAM: prolipoprotein diacylglyceryl transferase; SPTR: Prolipoprotein diacylglyceryl transferase; TIGRFAM: prolipoprotein diacylglyceryl transferase; PFAM: Prolipoprotein diacylglyceryl transferase; TIGRFAM: prolipoprotein diacylglyceryl transferase YP_004160286.1 COGs: COG3279 Response regulator of the LytR/AlgR family; InterPro IPR007492; KEGG: bfr:BF3236 hypothetical protein; PFAM: LytTr DNA-binding region; SPTR: uncharacterized protein; PFAM: LytTr DNA-binding domain YP_004160287.1 KEGG: bvu:BVU_1144 hypothetical protein; SPTR: uncharacterized protein YP_004160288.1 COGs: COG0249 Mismatch repair ATPase (MutS family); InterProIPR007695: IPR007860: IPR007696: IPR007861: IPR 000432: IPR005748; KEGG: bth:BT_3121 DNA mismatch repair protein MutS; PFAM: MutS III domain protein; DNA mismatch repair protein MutS domain protein; MutS II domain protein; MutS IV domain protein; SMART: DNA mismatch repair protein MutS domain protein; MutS III domain protein; SPTR: DNA mismatch repair protein mutS; TIGRFAM: DNA mismatch repair protein MutS; PFAM: MutS family domain IV; MutS domain II; MutS domain V; MutS domain I; MutS domain III; TIGRFAM: DNA mismatch repair protein MutS YP_004160289.1 COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterProIPR020449: IPR013096: IPR000005: IPR018062: IPR 018060; KEGG: rbi:RB2501_01955 activator protein MtlR; PFAM: cupin; helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: uncharacterized protein; PFAM: Cupin domain; Bacterial regulatory helix-turn-helix proteins, AraC family YP_004160290.1 COGs: COG1835 acyltransferase; InterPro IPR002656; KEGG: tva:TVAG_195940 Acyltransferase; PFAM: acyltransferase; SPTR: Predicted acyltransferases; PFAM: Acyltransferase YP_004160291.1 InterPro IPR004360; KEGG: str:Sterm_3504 glyoxalase/bleomycin resistance protein/dioxygenase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; SPTR: Glyoxalase/bleomycin resistance protein/dioxygenase; PFAM: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily YP_004160292.1 InterPro IPR005902; KEGG: pgn:PGN_1415 DNA-binding protein histone-like family; SPTR: uncharacterized protein; TIGRFAM: DNA-binding protein; TIGRFAM: DNA-binding protein, histone-like YP_004160293.1 KEGG: cts:Ctha_1865 filamentous haemagglutinin family outer membrane protein; SPTR: The glug motif domain protein YP_004160294.1 KEGG: pno:SNOG_03182 hypothetical protein; SPTR: uncharacterized protein YP_004160295.1 KEGG: bta:785813 leptin receptor-like; SPTR: uncharacterized protein YP_004160296.1 InterPro IPR011600; KEGG: sli:Slin_6462 hypothetical protein; PFAM: peptidase C14 caspase catalytic subunit p20; SPTR: uncharacterized protein; PFAM: Caspase domain YP_004160297.1 KEGG: cho:Chro.60235 hypothetical protein; SPTR: uncharacterized protein YP_004160298.1 COGs: COG1704 conserved hypothetical protein; InterPro IPR007156; KEGG: bth:BT_1897 hypothetical protein; PFAM: LemA family protein; SPTR: uncharacterized protein; PFAM: LemA family YP_004160299.1 KEGG: bth:BT_1898 hypothetical protein; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF3137) YP_004160300.1 KEGG: mmu:104069 synuclein, beta; SPTR: Beta-synuclein YP_004160301.1 KEGG: llo:LLO_0786 transmembrane protein YP_004160302.1 InterPro IPR020449: IPR000005: IPR018062: IPR018060; KEGG: bvu:BVU_2093 transcriptional regulator; PFAM: helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: uncharacterized protein; PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family YP_004160303.1 InterPro IPR000415; KEGG: fma:FMG_1514 nitroreductase; PFAM: nitroreductase; SPTR: uncharacterized protein; PFAM: Nitroreductase YP_004160304.1 InterPro IPR005902; KEGG: bth:BT_0615 hypothetical protein; SPTR: uncharacterized protein; TIGRFAM: DNA-binding protein; TIGRFAM: DNA-binding protein, histone-like YP_004160305.1 COGs: COG1733 transcriptional regulator protein; InterPro IPR002577; KEGG: bvu:BVU_2064 transcriptional regulator; PFAM: helix-turn-helix HxlR type; SPTR: uncharacterized protein; PFAM: HxlR-like helix-turn-helix YP_004160306.1 KEGG: bth:BT_2087 hypothetical protein; SPTR: uncharacterized protein YP_004160307.1 InterPro IPR000620; KEGG: bth:BT_3123 hypothetical protein; PFAM: protein of unknown function DUF6 transmembrane; SPTR: uncharacterized protein; PFAM: EamA-like transporter family YP_004160308.1 COGs: COG0495 Leucyl-tRNA synthetase; InterProIPR002302: IPR015413: IPR002300: IPR013155: IPR 001412; KEGG: bth:BT_3126 leucyl-tRNA synthetase; PFAM: tRNA synthetase class I (M); aminoacyl-tRNA synthetase class Ia; tRNA synthetase valyl/leucyl anticodon-binding; SPTR: Leucyl-tRNA synthetase; TIGRFAM: leucyl-tRNA synthetase; PFAM: tRNA synthetases class I (I, L, M and V); Anticodon-binding domain; tRNA synthetases class I (M); TIGRFAM: leucyl-tRNA synthetase, eubacterial and mitochondrial family YP_004160309.1 COGs: COG1284 conserved hypothetical protein; InterPro IPR003740: IPR019264; KEGG: bfs:BF4373 transmembrane protein; PFAM: Protein of unknown function DUF2179; protein of unknown function DUF161; SPTR: uncharacterized protein; PFAM: Uncharacterized BCR, YitT family COG1284; Uncharacterized protein conserved in bacteria (DUF2179) YP_004160310.1 COGs: COG0127 Xanthosine triphosphate pyrophosphatase; InterPro IPR002637: IPR020922; KEGG: bvu:BVU_1146 deoxyribonucleoside-triphosphatase; PFAM: Ham1 family protein; SPTR: Nucleoside-triphosphatase; TIGRFAM: non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; PFAM: Ham1 family; TIGRFAM: non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family YP_004160311.1 COGs: COG0379 Quinolinate synthase; InterPro IPR003473; KEGG: bth:BT_3164 quinolinate synthetase; PFAM: Quinolinate synthetase A; PRIAM: Quinolinate synthase; SPTR: uncharacterized protein; TIGRFAM: quinolinate synthetase complex, A subunit; PFAM: Quinolinate synthetase A protein; TIGRFAM: quinolinate synthetase complex, A subunit YP_004160312.1 COGs: COG0566 rRNA methylase; InterPro IPR001537; KEGG: bfs:BF0001 SpoU rRNA methylase; PFAM: tRNA/rRNA methyltransferase (SpoU); SPTR: uncharacterized protein; PFAM: SpoU rRNA methylase YP_004160313.1 COGs: COG1284 conserved hypothetical protein; InterPro IPR003740: IPR019264; KEGG: cbl:CLK_2824 hypothetical protein; PFAM: Protein of unknown function DUF2179; protein of unknown function DUF161; SPTR: uncharacterized protein; PFAM: Uncharacterized BCR, YitT family COG1284; Uncharacterized protein conserved in bacteria (DUF2179) YP_004160314.1 COGs: COG0642 Signal transduction histidine kinase; InterPro IPR004358: IPR003661: IPR003594: IPR005467; KEGG: bth:BT_0654 two-component sensor histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: two-component sensor histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain YP_004160315.1 KEGG: bfs:BF0012 hypothetical protein; SPTR: uncharacterized protein YP_004160316.1 KEGG: bth:BT_3167 hypothetical protein; SPTR: uncharacterized protein YP_004160317.1 COGs: COG0731 Fe-S oxidoreductase; InterPro IPR007197; KEGG: bvu:BVU_1140 Fe-S oxidoreductase; PFAM: radical SAM protein; SPTR: uncharacterized protein; PFAM: Radical SAM superfamily YP_004160318.1 InterPro IPR001969; KEGG: hch:HCH_00467 PDZ domain-containing protein; SPTR: Protein containing PDZ domain; PFAM: Retroviral aspartyl protease YP_004160319.1 COGs: COG1864 DNA/RNA endonuclease G NUC1; InterPro IPR001604: IPR018524: IPR020821; KEGG: bvu:BVU_4053 endonuclease; PFAM: DNA/RNA non-specific endonuclease; SMART: Extracellular Endonuclease, subunit A; SPTR: uncharacterized protein; PFAM: DNA/RNA non-specific endonuclease YP_004160320.1 COGs: COG0659 Sulfate permease and related transporter (MFS superfamily); InterPro IPR011547: IPR002645: IPR001902; KEGG: bth:BT_3181 sulfate transporter, permease; PFAM: sulphate transporter; Sulfate transporter/antisigma-factor antagonist STAS; SPTR: uncharacterized protein; TIGRFAM: sulfate transporter; manually curated; PFAM: Sulfate transporter family; STAS domain; TIGRFAM: anti-anti-sigma factor; high affinity sulphate transporter 1 YP_004160321.1 KEGG: bth:BT_3183 hypothetical protein; SPTR: uncharacterized protein YP_004160322.1 COGs: COG1592 Rubrerythrin; InterPro IPR003251: IPR004039: IPR009040; KEGG: bfs:BF0020 rubrerythrin; PFAM: Rubrerythrin; SPTR: uncharacterized protein; PFAM: Rubrerythrin YP_004160323.1 InterPro IPR013096; KEGG: bfs:BF4112 hypothetical protein; PFAM: cupin; SPTR: uncharacterized protein; PFAM: Cupin domain YP_004160324.1 COGs: COG2273 Beta-glucanase/Beta-glucan synthetase; InterPro IPR000757; KEGG: bth:BT_2550 beta-glucanase precursor; PFAM: glycoside hydrolase 16; SPTR: Beta-glucanase; PFAM: glycosyl hydrolases family 16 YP_004160325.1 InterPro IPR018247; KEGG: bth:BT_4224 hypothetical protein; SPTR: uncharacterized protein YP_004160326.1 KEGG: pgi:PG2134 lipoprotein; SPTR: uncharacterized protein YP_004160327.1 InterPro IPR014941: IPR019775; KEGG: bvu:BVU_0901 hypothetical protein; PFAM: protein of unknown function DUF1812; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF1812) YP_004160328.1 KEGG: bfr:BF2997 hypothetical protein; SPTR: uncharacterized protein YP_004160329.1 KEGG: bvu:BVU_0907 hypothetical protein; SPTR: uncharacterized protein; PFAM: OmpA family YP_004160330.1 KEGG: bfr:BF2124 hypothetical protein; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF3575) YP_004160331.1 COGs: COG0029 Aspartate oxidase; InterPro IPR013027: IPR003953: IPR004112: IPR005288; KEGG: bvu:BVU_1113 exported L-aspartate oxidase; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; SPTR: uncharacterized protein; TIGRFAM: L-aspartate oxidase; PFAM: domain; FAD binding domain; TIGRFAM: L-aspartate oxidase YP_004160332.1 KEGG: bth:BT_3185 hypothetical protein; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF1200) YP_004160333.1 COGs: COG3279 Response regulator of the LytR/AlgR family; InterPro IPR007492; KEGG: pdi:BDI_3357 two-component system response regulator; PFAM: LytTr DNA-binding region; SPTR: uncharacterized protein; PFAM: LytTr DNA-binding domain YP_004160334.1 KEGG: bfs:BF3189 hypothetical protein; SPTR: uncharacterized protein YP_004160335.1 KEGG: bth:BT_1786 hypothetical protein; SPTR: uncharacterized protein YP_004160336.1 InterPro IPR006652; KEGG: bfs:BF3187 hypothetical protein; PFAM: Kelch repeat type 1-containing protein; SPTR: uncharacterized protein; PFAM: Kelch motif YP_004160337.1 KEGG: bth:BT_1788 hypothetical protein; SPTR: uncharacterized protein YP_004160338.1 KEGG: bfs:BF0409 hypothetical protein; SPTR: Hypothetical exported protein YP_004160339.1 KEGG: bfs:BF0061 hypothetical protein; SPTR: uncharacterized protein; manually curated YP_004160340.1 KEGG: phe:Phep_4133 hypothetical protein; SPTR: Predicted protein YP_004160341.1 KEGG: bfs:BF4290 hypothetical protein; SPTR: uncharacterized protein YP_004160342.1 COGs: COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3); InterProIPR013027: IPR000815: IPR004099: IPR006258: IPR 012999; KEGG: bfs:BF0023 dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; SPTR: Dihydrolipoyl dehydrogenase; TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; TIGRFAM: dihydrolipoamide dehydrogenase YP_004160343.1 KEGG: bfs:BF1337 hypothetical protein; SPTR: uncharacterized protein YP_004160344.1 COGs: COG2027 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4); InterPro IPR000667; KEGG: bfr:BF0025 D-alanyl-D-alanine carboxypeptidase; PFAM: peptidase S13 D-Ala-D-Ala carboxypeptidase C; PRIAM: Serine-type D-Ala-D-Ala carboxypeptidase; SPTR: uncharacterized protein; TIGRFAM: D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase; PFAM: D-Ala-D-Ala carboxypeptidase 3 (S13) family; TIGRFAM: D-alanyl-D-alanine carboxypeptidase, serine-type, PBP4 family YP_004160345.1 COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR000005: IPR018060; KEGG: bth:BT_2939 transcriptional regulator; PFAM: helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: Transcriptional regulator; PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family YP_004160346.1 COGs: COG0845 Membrane-fusion protein; InterPro IPR006143; KEGG: bth:BT_2940 multidrug resistance protein; PFAM: hemolysin D; SPTR: uncharacterized protein; TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: HlyD family secretion protein; TIGRFAM: RND family efflux transporter, MFP subunit YP_004160347.1 COGs: COG0841 Cation/multidrug efflux pump; InterPro IPR001036: IPR004764: IPR006162: IPR019756; KEGG: bth:BT_2941 multidrug resistance protein MexB (multidrug-efflux protein); PFAM: acriflavin resistance protein; SPTR: RND efflux system, inner membrane transporter CmeB; TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: AcrB/AcrD/AcrF family; TIGRFAM: The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family YP_004160348.1 COGs: COG1538 Outer membrane protein; InterPro IPR003423: IPR010131; KEGG: bth:BT_2942 multidrug resistance protein; PFAM: outer membrane efflux protein; SPTR: uncharacterized protein; TIGRFAM: RND efflux system, outer membrane lipoprotein, NodT family; PFAM: Outer membrane efflux protein; TIGRFAM: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family YP_004160349.1 COGs: COG0427 Acetyl-CoA hydrolase; InterPro IPR003702: IPR017821; KEGG: bth:BT_3193 coenzyme A transferase; PFAM: acetyl-CoA hydrolase/transferase; PRIAM: Acetyl-CoA hydrolase; SPTR: uncharacterized protein; TIGRFAM: succinate CoA transferase; PFAM: Acetyl-CoA hydrolase/transferase N-terminal domain; Citrate lyase, alpha subunit (CitF); TIGRFAM: succinate CoA transferases YP_004160350.1 KEGG: bfs:BF0026 hypothetical protein; SPTR: uncharacterized protein YP_004160351.1 COGs: COG0621 2-methylthioadenine synthetase; InterProIPR013848: IPR007197: IPR002792: IPR005839: IPR 006463: IPR020612: IPR006638; KEGG: bth:BT_3195 (dimethylallyl)adenosine tRNA methylthiotransferase; PFAM: protein of unknown function UPF0004; radical SAM protein; deoxyribonuclease/rho motif-related TRAM; SMART: Elongator protein 3/MiaB/NifB; SPTR: tRNA-I(6)A37 thiotransferase; TIGRFAM: RNA modification enzyme, MiaB family; tRNA-i(6)A37 thiotransferase enzyme MiaB; PFAM: TRAM domain; Radical SAM superfamily; Uncharacterized protein family UPF0004; TIGRFAM: tRNA-N(6)-(isopentenyl)adenosine-37 thiotransferase enzyme MiaB; RNA modification enzyme, MiaB family YP_004160352.1 InterPro IPR005151: IPR006162; KEGG: tle:Tlet_1253 peptidase S41; PFAM: peptidase S41; SPTR: peptidase S41; PFAM: peptidase S41 YP_004160353.1 KEGG: bth:BT_2500 hypothetical protein; SPTR: uncharacterized protein YP_004160354.1 InterPro IPR013217; KEGG: bfr:BF0053 hypothetical protein; PFAM: methyltransferase type 12; SPTR: uncharacterized protein; manually curated; PFAM: methyltransferase domain YP_004160355.1 COGs: COG2177 Cell division protein; InterPro IPR003838; KEGG: bfs:BF0066 cell division protein; PFAM: protein of unknown function DUF214; SPTR: uncharacterized protein; PFAM: Predicted permease YP_004160356.1 KEGG: bth:BT_3211 hypothetical protein; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF3098) YP_004160357.1 COGs: COG1968 Uncharacterized bacitracin resistance protein; InterPro IPR003824; KEGG: pgi:PG1538 undecaprenol kinase, PFAM: Bacitracin resistance protein BacA; SPTR: uncharacterized protein; TIGRFAM: undecaprenol kinase; PFAM: Bacitracin resistance protein BacA; TIGRFAM: UDP-diphosphatase UppP YP_004160358.1 COGs: COG0130 Pseudouridine synthase; InterPro IPR002501: IPR014780; KEGG: bfs:BF0069 tRNA pseudouridine synthase; PFAM: pseudouridylate synthase TruB domain protein; SPTR: uncharacterized protein; TIGRFAM: tRNA pseudouridine synthase B; PFAM: TruB family pseudouridylate synthase (N terminal domain); TIGRFAM: tRNA pseudouridine 55 synthase YP_004160359.1 COGs: COG0809 S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase); InterPro IPR003699; KEGG: bfs:BF0070 S-adenosylmethionine:tRNA ribosyltransferase-isomerase; PFAM: Queuosine biosynthesis protein; SPTR: uncharacterized protein; TIGRFAM:S-adenosylmethionine/tRNA-ribosyltransferas e-isomerase; PFAM: Queuosine biosynthesis protein; TIGRFAM: S-adenosylmethionine:tRNA ribosyltransferase-isomerase YP_004160360.1 COGs: COG0801 7 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase; InterPro IPR000550; KEGG: bfs:BF0071 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase (HppK); PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK; PRIAM:2-amino-4-hydroxy-6-hydroxymethyldihydropteri dinediphosphokinase; SPTR: 7, 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase; TIGRFAM:2-amino-4-hydroxy-6-hydroxymethyldihydropte ridinepyrophosphokinase; PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK); TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase YP_004160361.1 InterPro IPR005135: IPR010916; KEGG: bvu:BVU_0084 endonuclease/exonuclease/phosphatase; PFAM: Endonuclease/exonuclease/phosphatase; SPTR: uncharacterized protein; PFAM: Endonuclease/Exonuclease/phosphatase YP_004160362.1 KEGG: cbr:CBG09235 Hypothetical protein CBG09235; SPTR: CrcB-like protein YP_004160364.1 COGs: COG0192 S-adenosylmethionine synthetase; InterPro IPR002133; KEGG: bth:BT_3219 S-adenosylmethionine synthetase; PFAM: S-adenosylmethionine synthetase; PRIAM: methionine adenosyltransferase; SPTR: S-adenosylmethionine synthase; TIGRFAM: S-adenosylmethionine synthetase; PFAM: S-adenosylmethionine synthetase, C-terminal domain; S-adenosylmethionine synthetase, central domain; S-adenosylmethionine synthetase, N-terminal domain; TIGRFAM: S-adenosylmethionine synthetase YP_004160365.1 KEGG: pru:PRU_1399 hypothetical protein; SPTR: uncharacterized protein YP_004160366.1 COGs: COG1611 Rossmann fold nucleotide-binding protein; InterPro IPR005269; KEGG: bth:BT_3224 lysine decarboxylase; PFAM: Conserved hypothetical protein CHP00730; SPTR: uncharacterized protein; PFAM: Possible lysine decarboxylase; TIGRFAM: conserved hypothetical protein, DprA/Smf-related, family 1; conserved hypothetical protein, DprA/Smf-related, family 2 YP_004160367.1 KEGG: bfs:BF0074 hypothetical protein; SPTR: uncharacterized protein YP_004160368.1 COGs: COG1587 Uroporphyrinogen-III synthase; InterPro IPR003754; KEGG: bfs:BF0075 uroporphyrinogen-III synthase; PFAM: Uroporphyrinogen III synthase HEM4; SPTR: uncharacterized protein; PFAM: Uroporphyrinogen-III synthase HemD YP_004160369.1 InterPro IPR000100: IPR020539; KEGG: bfs:BF0076 ribonuclease P; PFAM: ribonuclease P protein; SPTR: Ribonuclease P protein component; TIGRFAM: ribonuclease P protein component; PFAM: Ribonuclease P; TIGRFAM: ribonuclease P protein component, eubacterial YP_004160370.1 COGs: COG0759 conserved hypothetical protein; InterPro IPR002696; KEGG: bfs:BF0077 hypothetical protein; PFAM: protein of unknown function DUF37; SPTR: UPF0161 protein HMPREF0969_01681; PFAM: Domain of unknown function DUF37; TIGRFAM: conserved hypothetical protein YidD YP_004160371.1 COGs: COG0084 Mg-dependent DNase; InterPro IPR001130: IPR012278; KEGG: bfs:BF0078 TatD-related DNase; PFAM: TatD-related deoxyribonuclease; SPTR: uncharacterized protein; PFAM: TatD related DNase YP_004160372.1 COGs: COG0162 Tyrosyl-tRNA synthetase; InterPro IPR002307: IPR002305: IPR001412: IPR002942; KEGG: bvu:BVU_1191 tyrosyl-tRNA synthetase 1; PFAM: aminoacyl-tRNA synthetase class Ib; PRIAM: Tyrosine--tRNA ligase; SPTR: uncharacterized protein; TIGRFAM: tyrosyl-tRNA synthetase; PFAM: tRNA synthetases class I (W and Y); TIGRFAM: tyrosyl-tRNA synthetase YP_004160373.1 COGs: COG2348 Uncharacterized protein involved in methicillin resistance; InterPro IPR003447; KEGG: pdi:BDI_3860 femAB family protein; PFAM: methicillin resistance protein; SPTR: FemAB family protein; manually curated; PFAM: FemAB family YP_004160374.1 COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR002347: IPR002198: IPR020904; KEGG: bvu:BVU_1106 gluconate 5-dehydrogenase; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: uncharacterized protein; PFAM: short chain dehydrogenase YP_004160375.1 KEGG: bfs:BF0084 hypothetical protein; SPTR: uncharacterized protein YP_004160376.1 COGs: COG0726 xylanase/chitin deacetylase; InterPro IPR002509; KEGG: bfs:BF0086 polysaccharide deacetylase; PFAM: polysaccharide deacetylase; SPTR: polysaccharide deacetylase; PFAM: polysaccharide deacetylase YP_004160377.1 KEGG: bth:BT_3247 hypothetical protein; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF2723) YP_004160379.1 SPTR: uncharacterized protein YP_004160380.1 InterPro IPR002241: IPR000111: IPR005084; KEGG: bvu:BVU_0640 glycoside hydrolase; PFAM: glycoside hydrolase clan GH-D; PRIAM: alpha-galactosidase; SPTR: alpha-galactosidase; PFAM: Melibiase YP_004160381.1 KEGG: bfs:BF4033 hypothetical protein; SPTR: uncharacterized protein YP_004160382.1 COGs: COG1121 ABC-type Mn/Zn transport systems ATPase component; InterPro IPR003439: IPR017871: IPR003593; KEGG: bth:BT_3248 metal ABC transporter, ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: uncharacterized protein; PFAM: ABC transporter YP_004160383.1 KEGG: rba:RB11540 signal peptide; SPTR: uncharacterized protein YP_004160384.1 COGs: COG0803 ABC-type metal ion transport system periplasmic component/surface adhesin; InterPro IPR006128: IPR006127; KEGG: bfs:BF0092 metal ABC transporter substrate-binding precursor; PFAM: periplasmic solute binding protein; SPTR: uncharacterized protein; PFAM: Periplasmic solute binding protein family YP_004160385.1 COGs: COG4121 conserved hypothetical protein; InterPro IPR008471; KEGG: bth:BT_3250 hypothetical protein; PFAM: protein of unknown function DUF752; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF752) YP_004160386.1 COGs: COG1238 membrane protein; InterPro IPR015414: IPR020143; KEGG: bfs:BF0094 transmembrane protein; PFAM: SNARE associated Golgi protein; SPTR: uncharacterized protein; PFAM: SNARE associated Golgi protein YP_004160387.1 KEGG: bfs:BF0095 transmembrane protein; SPTR: uncharacterized protein YP_004160388.1 COGs: COG0151 phosphoribosylamine-glycine ligase; InterProIPR020562: IPR020561: IPR020560: IPR000115: IPR 011761; KEGG: bth:BT_3253 phosphoribosylamine--glycine ligase; PFAM: phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; phosphoribosylglycinamide synthetase, N-domain; phosphoribosylglycinamide synthetase, C-domain; PRIAM: phosphoribosylamine--glycine ligase; SPTR: uncharacterized protein; TIGRFAM: phosphoribosylamine/glycine ligase; PFAM: phosphoribosylglycinamide synthetase, N domain; phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; phosphoribosylglycinamide synthetase, C domain; TIGRFAM: phosphoribosylamine--glycine ligase YP_004160389.1 COGs: COG1506 Dipeptidyl aminopeptidase/acylaminoacyl-peptidase; InterPro IPR002469; KEGG: bfs:BF0097 exported dipeptidyl peptidase IV; PFAM: peptidase S9B dipeptidylpeptidase IV domain protein; SPTR: uncharacterized protein; PFAM: Prolyl oligopeptidase; Dipeptidyl peptidase IV (DPP IV) N-terminal region YP_004160390.1 COGs: COG0116 N6-adenine-specific DNA methylase; InterPro IPR004114: IPR000241: IPR002052; KEGG: bth:BT_3255 N6-adenine-specific DNA methylase; PFAM: RNA methylase; THUMP domain-containing protein; PRIAM: rRNA (guanine-N(2)-)-methyltransferase; SPTR: uncharacterized protein; PFAM: RNA methylase UPF0020; THUMP domain YP_004160391.1 COGs: COG1045 Serine acetyltransferase; InterPro IPR001451; KEGG: bfs:BF0099 serine acetyltransferase; PRIAM: Serine O-acetyltransferase; SPTR: uncharacterized protein; TIGRFAM: serine O-acetyltransferase YP_004160392.1 COGs: COG0031 Cysteine synthase; InterPro IPR001926: IPR005856: IPR005859: IPR001216; KEGG: bfs:BF4362 cysteine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; SPTR: Cysteine synthase; TIGRFAM: cysteine synthase; cysteine synthase A; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: cysteine synthase A; cysteine synthases YP_004160393.1 COGs: COG3250 Beta-galactosidase/beta-glucuronidase; InterProIPR006101: IPR006104: IPR006102: IPR006103: IPR 004199: IPR000421: IPR000276; KEGG: bfs:BF3205 exported beta-galactosidase; PFAM: glycoside hydrolase 2; glycoside hydrolase 2 sugar binding; glycoside hydrolase 2 immunoglobulin domain protein beta-sandwich; glycoside hydrolase 42 domain 5 loop region; coagulation factor 5/8 type domain protein; SMART: coagulation factor 5/8 type domain protein; SPTR: uncharacterized protein; PFAM: F5/8 type C domain; domain; glycosyl hydrolases family 2, TIM barrel domain; glycosyl hydrolases family 2, sugar binding domain; Beta galactosidase small chain YP_004160394.1 InterPro IPR012944; KEGG: bvu:BVU_3711 hypothetical protein; PFAM: RagB/SusD domain protein; SPTR: outer membrane protein, probably involved in nutrient binding; PFAM: SusD family YP_004160395.1 COGs: COG4771 Outer membrane receptor for ferrienterochelin and colicins; InterPro IPR011662: IPR012910: IPR000531: IPR005479; KEGG: bvu:BVU_0959 hypothetical protein; PFAM: TonB-dependent receptor plug; Secretin/TonB short domain; TonB-dependent receptor; SPTR: outer membrane protein, probably involved in nutrient binding; PFAM: TonB dependent receptor; TonB-dependent Receptor Plug Domain; Secretin and TonB N terminus short domain YP_004160396.1 COGs: COG3712 Fe2+-dicitrate sensor membrane component; InterPro IPR006860: IPR012373; KEGG: bth:BT_1052 anti-sigma factor; PFAM: FecR protein; SPTR: uncharacterized protein; PFAM: FecR protein YP_004160397.1 COGs: COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog; InterPro IPR007627: IPR013249: IPR014284: IPR014327; KEGG: dfe:Dfer_2829 RNA polymerase, sigma-24 subunit, ECF subfamily; PFAM: Sigma-70 region 4 type 2; sigma-70 region 2 domain protein; SPTR: uncharacterized protein; TIGRFAM: RNA polymerase sigma-70 factor; RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; RNA polymerase sigma-70 factor, Bacteroides expansion family 1 YP_004160398.1 COGs: COG3467 flavin-nucleotide-binding protein; InterPro IPR011576; KEGG: bth:BT_3078 5-nitroimidazole antibiotic resistance protein; PFAM: pyridoxamine 5'-phosphate oxidase-related FMN-binding; SPTR: uncharacterized protein; PFAM: Pyridoxamine 5'-phosphate oxidase YP_004160399.1 KEGG: bgl:bglu_2g04620 membrane-anchored cell surface protein; SPTR: uncharacterized protein YP_004160400.1 COGs: COG0557 Exoribonuclease R; InterProIPR013223: IPR001900: IPR003029: IPR011805: IPR 004476; KEGG: bfs:BF4357 exoribonuclease; PFAM: ribonuclease II; Ribonuclease B OB region domain; RNA binding S1 domain protein; SPTR: Ribonuclease R; TIGRFAM: ribonuclease R; VacB and RNase II family 3'-5' exoribonuclease; PFAM: Ribonuclease B OB domain; RNB domain; S1 RNA binding domain; TIGRFAM: ribonuclease R; VacB and RNase II family 3'-5' exoribonucleases YP_004160401.1 COGs: COG0053 Co/Zn/Cd cation transporter; InterPro IPR002524; KEGG: bfs:BF4356 transmembrane cation efflux protein; PFAM: cation efflux protein; SPTR: uncharacterized protein; TIGRFAM: cation diffusion facilitator family transporter; PFAM: Cation efflux family; TIGRFAM: cation diffusion facilitator family transporter YP_004160402.1 COGs: COG0451 Nucleoside-diphosphate-sugar epimerase; InterPro IPR001509; KEGG: bfs:BF4355 UDP-glucose 4-epimerase; PFAM: NAD-dependent epimerase/dehydratase; SPTR: uncharacterized protein; PFAM: NAD dependent epimerase/dehydratase YP_004160403.1 InterPro IPR000326; KEGG: bfs:BF4354 transmembrane protein; PFAM: phosphoesterase PA-phosphatase related; SPTR: uncharacterized protein; PFAM: PAP2 superfamily YP_004160404.1 COGs: COG0042 tRNA-dihydrouridine synthase; InterPro IPR001269: IPR004652: IPR018517; KEGG: bth:BT_3073 dehydrogenase; PFAM: dihydrouridine synthase DuS; SPTR: uncharacterized protein; TIGRFAM: TIM-barrel protein, nifR3 family; PFAM: Dihydrouridine synthase (Dus); TIGRFAM: TIM-barrel protein, nifR3 family; tRNA dihydrouridine synthase A YP_004160405.1 InterPro IPR018637; KEGG: bfs:BF4352 hypothetical protein; PFAM: Protein of unknown function DUF2059; SPTR: uncharacterized protein; PFAM: Uncharacterized protein conserved in bacteria (DUF2059) YP_004160406.1 COGs: COG0826 Collagenase and related protease; InterPro IPR001539; KEGG: bth:BT_3072 collagenase precursor; PFAM: peptidase U32; SPTR: uncharacterized protein; PFAM: peptidase U32 YP_004160407.1 COGs: COG0824 thioesterase; InterPro IPR006683; KEGG: bfs:BF4350 thioesterase; PFAM: thioesterase superfamily protein; SPTR: uncharacterized protein; PFAM: Thioesterase superfamily; TIGRFAM: acyl-CoA thioester hydrolase, YbgC/YbaW family YP_004160408.1 COGs: COG0758 Rossmann fold nucleotide-binding protein involved in DNA uptake; InterPro IPR003488; KEGG: bfs:BF4349 DNA processing smf-like protein; PFAM: SMF family protein; SPTR: uncharacterized protein; TIGRFAM: DNA protecting protein DprA; PFAM: DNA recombination-mediator protein A; TIGRFAM: DNA protecting protein DprA YP_004160409.1 COGs: COG0584 glycerophosphoryl diester phosphodiesterase; InterPro IPR004129; KEGG: bfr:BF4444 glycerophosphoryl diester phosphodiesterase; PFAM: glycerophosphoryl diester phosphodiesterase; SPTR: uncharacterized protein; PFAM: glycerophosphoryl diester phosphodiesterase YP_004160410.1 InterPro IPR008254; KEGG: bfr:BF4307 flavodoxin; SPTR: Probable flavodoxin YP_004160411.1 KEGG: bfs:BF4370 hypothetical protein; SPTR: uncharacterized protein YP_004160412.1 COGs: COG0479 Succinate dehydrogenase/fumarate reductase Fe-S protein subunit; InterPro IPR006058: IPR017896: IPR001041: IPR004489; KEGG: bth:BT_3055 succinate dehydrogenase/fumarate reductase iron-sulfur subunit; PFAM: ferredoxin; SPTR: uncharacterized protein; TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; PFAM: 2Fe-2S iron-sulfur cluster binding domain; TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein YP_004160413.1 COGs: COG1053 Succinate dehydrogenase/fumarate reductase flavoprotein subunit; InterPro IPR003953: IPR004112: IPR011280; KEGG: bth:BT_3054 succinate dehydrogenase flavoprotein subunit; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; PRIAM: Succinate dehydrogenase; SPTR: uncharacterized protein; TIGRFAM: succinate dehydrogenase or fumarate reductase, flavoprotein subunit; PFAM: domain; FAD binding domain; TIGRFAM: succinate dehydrogenase or fumarate reductase, flavoprotein subunit, Bacillus subtilis subgroup YP_004160414.1 InterPro IPR011138; KEGG: bth:BT_3053 cytochrome b subunit; SPTR: uncharacterized protein; TIGRFAM: succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family; TIGRFAM: succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family YP_004160415.1 COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR018060; KEGG: bfs:BF4337 AraC family transcriptional regulator; SMART: Helix-turn-helix, AraC domain; SPTR: Transcriptional regulator YP_004160416.1 InterPro IPR000326; KEGG: bfs:BF4336 transmembrane PAP2-family protein; PFAM: phosphoesterase PA-phosphatase related; SMART: phosphoesterase PA-phosphatase related; SPTR: uncharacterized protein; PFAM: PAP2 superfamily YP_004160417.1 KEGG: bfr:BF1461 hypothetical protein; SPTR: uncharacterized protein YP_004160418.1 InterPro IPR000866: IPR017937: IPR017936; KEGG: cpi:Cpin_1833 alkyl hydroperoxide reductase/thiol specific antioxidant/Mal allergen; PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; SPTR: lipoprotein/thioderoxin; PFAM: AhpC/TSA family YP_004160419.1 KEGG: bfs:BF3824 hypothetical protein; SPTR: uncharacterized protein YP_004160420.1 KEGG: pdi:BDI_2997 hypothetical protein; SPTR: uncharacterized protein YP_004160421.1 COGs: COG0793 Periplasmic protease; InterPro IPR001478: IPR005151: IPR004447; KEGG: bfs:BF4335 carboxy-terminal processing protease precursor; PFAM: peptidase S41; PDZ/DHR/GLGF domain protein; SMART: peptidase S41; PDZ/DHR/GLGF domain protein; SPTR: uncharacterized protein; TIGRFAM: carboxyl-terminal protease; PFAM: peptidase S41; PDZ domain (Also known as DHR or GLGF); TIGRFAM: C-terminal peptidase (prc) YP_004160422.1 COGs: COG0669 phosphopantetheine adenylyltransferase; InterPro IPR001980: IPR004820: IPR004821; KEGG: bth:BT_3034 phosphopantetheine adenylyltransferase; PFAM: cytidylyltransferase; PRIAM: Pantetheine-phosphate adenylyltransferase; SPTR: phosphopantetheine adenylyltransferase; TIGRFAM: pantetheine-phosphate adenylyltransferase; cytidyltransferase-related domain protein; PFAM: Cytidylyltransferase; TIGRFAM: pantetheine-phosphate adenylyltransferase, bacterial; cytidyltransferase-related domain YP_004160423.1 COGs: COG0187 type IIA topoisomerase (DNA gyrase/topo II topoisomerase IV) B subunit; InterProIPR001241: IPR003594: IPR013506: IPR006171: IPR 018522; KEGG: bth:BT_3033 DNA topoisomerase IV subunit B; PFAM: DNA topoisomerase type IIA subunit B region 2 domain protein; ATP-binding region ATPase domain protein; TOPRIM domain-containing protein; SMART: DNA topoisomerase II; ATP-binding region ATPase domain protein; SPTR: uncharacterized protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; DNA gyrase B; DNA gyrase B subunit, carboxyl terminus YP_004160424.1 KEGG: bfs:BF4332 hypothetical protein; SPTR: uncharacterized protein YP_004160425.1 COGs: COG0530 Ca2+/Na+ antiporter; InterPro IPR004837: IPR004481; KEGG: bth:BT_3019 Na+/Ca2+ exchanger protein, cation antiporter; PFAM: sodium/calcium exchanger membrane region; SPTR: uncharacterized protein; TIGRFAM: Na+/Ca+ antiporter, CaCA family; PFAM: Sodium/calcium exchanger protein; TIGRFAM: K+-dependent Na+/Ca+ exchanger related-protein YP_004160426.1 COGs: COG0668 Small-conductance mechanosensitive channel; InterPro IPR006685: IPR005479; KEGG: bfr:BF4542 mechano-sensitive ion channel; PFAM: MscS Mechanosensitive ion channel; SPTR: uncharacterized protein; PFAM: Mechanosensitive ion channel YP_004160427.1 InterPro IPR004843; KEGG: bfs:BF4329 acid phosphatase; PFAM: metallophosphoesterase; SPTR: uncharacterized protein; PFAM: Calcineurin-like phosphoesterase YP_004160428.1 COGs: COG1629 Outer membrane receptor protein mostly Fe transport; InterPro IPR008454: IPR012910: IPR000531: IPR010104; KEGG: bfr:BF4539 TonB-dependent outer membrane protein; PFAM: TonB-dependent receptor; TonB-dependent receptor plug; Cna B domain protein; SPTR: uncharacterized protein; TIGRFAM: TonB-dependent receptor; PFAM: TonB dependent receptor; TonB-dependent Receptor Plug Domain; Cna protein B-type domain; TIGRFAM: TonB-dependent receptor YP_004160429.1 COGs: COG3119 Arylsulfatase A; InterPro IPR000917; KEGG: bvu:BVU_1045 sulfatase; PFAM: sulfatase; SPTR: sulfatase; PFAM: Sulfatase YP_004160430.1 COGs: COG3669 alpha-L-fucosidase; InterPro IPR000933; KEGG: bvu:BVU_1046 glycoside hydrolase; PRIAM: alpha-L-fucosidase; SMART: glycoside hydrolase 29 (alpha-L-fucosidase); SPTR: glycoside hydrolase 29; PFAM: alpha-L-fucosidase YP_004160431.1 COGs: COG3119 Arylsulfatase A; InterPro IPR000917; KEGG: bvu:BVU_1048 secreted sulfatase precursor; PFAM: sulfatase; SPTR: uncharacterized protein; PFAM: Sulfatase YP_004160432.1 KEGG: bth:BT_3008 hypothetical protein; SPTR: uncharacterized protein; PFAM: Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) YP_004160433.1 COGs: COG2173 D-alanyl-D-alanine dipeptidase; InterPro IPR000755; KEGG: bfs:BF4319 D-Ala-D-Ala dipeptidase; PFAM: peptidase M15D vanX D-ala-D-ala dipeptidase; SPTR: uncharacterized protein; PFAM: D-ala-D-ala dipeptidase YP_004160434.1 KEGG: bth:BT_4221 hypothetical protein; SPTR: uncharacterized protein YP_004160435.1 COGs: COG2268 conserved hypothetical protein; InterPro IPR001107; KEGG: bfs:BF0843 hypothetical protein; PFAM: band 7 protein; SMART: band 7 protein; SPTR: uncharacterized protein; PFAM: SPFH domain / Band 7 family YP_004160436.1 KEGG: bvu:BVU_3843 hypothetical protein; SPTR: uncharacterized protein; manually curated YP_004160437.1 KEGG: bth:BT_2989 hypothetical protein; SPTR: uncharacterized protein YP_004160438.1 KEGG: tet:TTHERM_00584700 kinase domain containing protein; SPTR: Predicted protein YP_004160439.1 KEGG: ptm:GSPATT00033357001 hypothetical protein; SPTR: Predicted protein YP_004160440.1 InterPro IPR002104; KEGG: bth:BT_2986 integrase; PFAM: integrase; SPTR: Site-specific recombinase, phage integrase; PFAM: Phage integrase YP_004160441.1 InterPro IPR019069; KEGG: cyc:PCC7424_4451 hypothetical protein; PFAM: Restriction endonuclease, type II, ScaI; PRIAM: type II site-specific deoxyribonuclease; SPTR: NmeSIR; PFAM: ScaI restriction endonuclease YP_004160442.1 COGs: COG0863 DNA modification methylase; InterPro IPR001091: IPR002941: IPR017985; KEGG: cyc:PCC7424_4450 DNA methylase N-4/N-6 domain protein; PFAM: DNA methylase N-4/N-6 domain protein; SPTR: DNA methylase; PFAM: DNA methylase YP_004160443.1 InterPro IPR013838; KEGG: bvu:BVU_2298 hypothetical protein; SPTR: uncharacterized protein YP_004160444.1 KEGG: cgr:CaglfMp02 mitochondrial ribosomal protein VAR1; SPTR: uncharacterized protein YP_004160445.1 KEGG: pfh:PFHG_01091 conserved hypothetical protein; SPTR: uncharacterized protein YP_004160446.1 KEGG: pmx:PERMA_0093 TPR domain containing protein; SPTR: uncharacterized protein YP_004160447.1 KEGG: sto:ST1963 hypothetical protein; SPTR: uncharacterized protein; manually curated YP_004160448.1 KEGG: pfh:PFHG_01679 conserved hypothetical protein; SPTR: uncharacterized protein YP_004160449.1 KEGG: tva:TVAG_394820 hypothetical protein; SPTR: uncharacterized protein YP_004160451.1 InterPro IPR017937; KEGG: bfr:BF3457 hypothetical protein; SPTR: uncharacterized protein YP_004160452.1 KEGG: bth:BT_2980 transposase; SPTR: Transposase YP_004160453.1 KEGG: bfr:BF4517 hypothetical protein; SPTR: uncharacterized protein YP_004160454.1 COGs: COG1522 Transcriptional regulators; InterPro IPR000485: IPR019887: IPR019888; KEGG: bfs:BF4310 AsnC family transcriptional regulator; PFAM: Transcription regulator AsnC-type-like; SMART: Transcription regulator AsnC-type; SPTR: uncharacterized protein; PFAM: HTH domain; AsnC family YP_004160455.1 COGs: COG0545 FKBP-type peptidyl-prolyl cis-trans isomerase 1; InterPro IPR000774: IPR001179; KEGG: bth:BT_2977 peptidylprolyl isomerase; PFAM: peptidylprolyl isomerase FKBP-type; FKBP-type peptidyl-prolyl isomerase domain protein; SPTR: peptidyl-prolyl cis-trans isomerase; PFAM: FKBP-type peptidyl-prolyl cis-trans isomerase; Domain amino terminal to FKBP-type peptidyl-prolyl isomerase YP_004160456.1 COGs: COG0545 FKBP-type peptidyl-prolyl cis-trans isomerase 1; InterPro IPR000774: IPR001179; KEGG: bfs:BF4308 FkbP-type 22 kDa peptidyl-prolyl cis-trans isomerase; PFAM: peptidylprolyl isomerase FKBP-type; FKBP-type peptidyl-prolyl isomerase domain protein; PRIAM: peptidylprolyl isomerase; SPTR: peptidyl-prolyl cis-trans isomerase; PFAM: FKBP-type peptidyl-prolyl cis-trans isomerase; Domain amino terminal to FKBP-type peptidyl-prolyl isomerase YP_004160457.1 COGs: COG0846 NAD-dependent protein deacetylase SIR2 family; InterPro IPR003000; KEGG: bth:BT_2975 NAD-dependent deacetylase; PFAM: Silent information regulator protein Sir2; SPTR: uncharacterized protein; PFAM: Sir2 family YP_004160458.1 COGs: COG0463 glycosyltransferase involved in cell wall biogenesis; InterPro IPR001173; KEGG: bth:BT_2947 glycosyltransferase; PFAM: glycosyl transferase 2; SPTR: uncharacterized protein; PFAM: glycosyl transferase 2 YP_004160459.1 COGs: COG0438 glycosyltransferase; InterPro IPR001296; KEGG: bfs:BF4305 glycosyltransferase; PFAM: glycosyl transferase group 1; SPTR: uncharacterized protein; manually curated; PFAM: glycosyl transferases group 1 YP_004160460.1 COGs: COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase; InterPro IPR001732: IPR014026: IPR014027: IPR017476; KEGG: bfs:BF4304 UDP-N-acetyl-D-mannosamine dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase; SPTR: UDP-N-acetyl-D-mannosamine dehydrogenase; TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase, NAD binding domain; UDP-glucose/GDP-mannose dehydrogenase, central domain; UDP-glucose/GDP-mannose dehydrogenase, UDP binding domain; TIGRFAM: nucleotide sugar dehydrogenase YP_004160461.1 COGs: COG0381 UDP-N-acetylglucosamine 2-epimerase; InterPro IPR003331; KEGG: bfr:BF4509 UDP-N-acetylglucosamine 2-epimerase; PFAM: UDP-N-acetylglucosamine 2-epimerase; PRIAM: UDP-N-acetylglucosamine 2-epimerase; SPTR: UDP-N-acetylglucosamine 2-epimerase; TIGRFAM: UDP-N-acetylglucosamine 2-epimerase; PFAM: UDP-N-acetylglucosamine 2-epimerase; TIGRFAM: UDP-N-acetylglucosamine 2-epimerase YP_004160462.1 COGs: COG0438 glycosyltransferase; InterPro IPR001296; KEGG: bfr:BF4507 glycosyltransferase; PFAM: glycosyl transferase group 1; SPTR: glycosyltransferase; PFAM: glycosyl transferases group 1 YP_004160463.1 InterPro IPR001296; KEGG: bth:BT_2937 glycosyltransferase; PFAM: glycosyl transferase group 1; SPTR: glycosyltransferase; PFAM: glycosyl transferases group 1 YP_004160464.1 COGs: COG0438 glycosyltransferase; InterPro IPR001296; KEGG: bth:BT_2936 glycosyltransferase; PFAM: glycosyl transferase group 1; SPTR: glycosyltransferase; PFAM: glycosyl transferases group 1 YP_004160465.1 InterPro IPR021141; KEGG: dfe:Dfer_0169 glycosyl transferase 14; PFAM: Core-2/I-Branching enzyme; SPTR: uncharacterized protein; PFAM: Core-2/I-Branching enzyme YP_004160466.1 COGs: COG2244 Membrane protein involved in the export of O-antigen and teichoic acid; InterPro IPR002797; KEGG: bth:BT_2934 transmembrane transport protein, lipopolysaccharide biosynthesis protein; PFAM: polysaccharide biosynthesis protein; SPTR: uncharacterized protein; PFAM: polysaccharide biosynthesis protein YP_004160467.1 COGs: COG0143 methionyl-tRNA synthetase; InterProIPR014758: IPR015413: IPR002547: IPR002304: IPR 004495: IPR001412; KEGG: bvu:BVU_0882 methionyl-tRNA synthetase; PFAM: tRNA synthetase class I (M); tRNA-binding protein; PRIAM: methionine--tRNA ligase; SPTR: uncharacterized protein; TIGRFAM: methionyl-tRNA synthetase; methionyl-tRNA synthetase, beta subunit; PFAM: Anticodon-binding domain; tRNA synthetases class I (M); tRNA binding domain; TIGRFAM: methionyl-tRNA synthetase C-terminal region/beta chain; methionyl-tRNA synthetase YP_004160468.1 KEGG: cat:CA2559_00400 hypothetical protein; SPTR: uncharacterized protein YP_004160469.1 COGs: COG3943 Virulence protein; KEGG: bth:BT_p548233 DNA-binding protein; SPTR: Toxin-antitoxin system, toxin component, Fic family YP_004160470.1 COGs: COG3943 Virulence protein; KEGG: bth:BT_p548233 DNA-binding protein; SPTR: DNA-binding protein YP_004160471.1 COGs: COG3943 Virulence protein; KEGG: bth:BT_p548233 DNA-binding protein; SPTR: Toxin-antitoxin system, toxin component, Fic family YP_004160472.1 KEGG: cth:Cthe_1890 cellulosome enzyme, dockerin type I; SPTR: Cellulosome enzyme, dockerin type I YP_004160473.1 KEGG: tad:TRIADDRAFT_51438 hypothetical protein; SPTR: uncharacterized protein YP_004160474.1 KEGG: bth:BT_3061 hypothetical protein; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF3575) YP_004160475.1 COGs: COG1042 Acyl-CoA synthetase (NDP forming); InterPro IPR003781: IPR011761; KEGG: bth:BT_2924 acetyl-CoA synthetase; PFAM: CoA-binding domain protein; SPTR: uncharacterized protein; PFAM: CoA binding domain YP_004160476.1 COGs: COG0606 ATPase with chaperone activity; InterProIPR001208: IPR000523: IPR004482: IPR002078: IPR 003593; KEGG: bth:BT_2846 magnesium chelatase, subunit ChlI; PFAM: magnesium chelatase ChlI subunit; SMART: AAA ATPase; SPTR: Mg chelatase; TIGRFAM: Mg chelatase, subunit ChlI; PFAM: Magnesium chelatase, subunit ChlI; TIGRFAM: Mg chelatase-related protein YP_004160477.1 InterPro IPR000866: IPR017936; KEGG: bfr:BF4486 hypothetical protein; PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; SPTR: uncharacterized protein; PFAM: AhpC/TSA family YP_004160478.1 InterPro IPR001440: IPR019734: IPR013026; KEGG: bfs:BF4280 hypothetical protein; PFAM: hypothetical protein; SMART: Tetratricopeptide repeat; SPTR: uncharacterized protein; PFAM: Tetratricopeptide repeat YP_004160479.1 COGs: COG4974 Site-specific recombinase XerD; InterPro IPR004107: IPR002104: IPR011932; KEGG: bfs:BF4279 tyrosine recombinase; PFAM: integrase; integrase domain protein SAM domain protein; SPTR: Tyrosine recombinase XerD; TIGRFAM: tyrosine recombinase XerD; PFAM: Phage integrase, N-terminal SAM-like domain; Phage integrase; TIGRFAM: tyrosine recombinase XerD YP_004160480.1 COGs: COG0757 3-dehydroquinate dehydratase II; InterPro IPR001874: IPR018509; KEGG: bth:BT_2842 3-dehydroquinate dehydratase; PFAM: dehydroquinase class II; PRIAM: 3-dehydroquinate dehydratase; SPTR: uncharacterized protein; TIGRFAM: 3-dehydroquinate dehydratase, type II; PFAM: Dehydroquinase class II; TIGRFAM: 3-dehydroquinate dehydratase, type II YP_004160481.1 COGs: COG0469 Pyruvate kinase; InterPro IPR015793: IPR015794: IPR001697: IPR018209; KEGG: bfs:BF4277 pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; PRIAM: Pyruvate kinase; SPTR: Pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase, barrel domain; Pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase YP_004160482.1 COGs: COG4122 O-methyltransferase; InterPro IPR002935; KEGG: bfs:BF4276 O-methyltransferase; PFAM: O-methyltransferase 3; SPTR: uncharacterized protein; PFAM: O-methyltransferase YP_004160483.1 COGs: COG1538 Outer membrane protein; InterPro IPR003423; KEGG: bfr:BF2093 outer membrane efflux protein; PFAM: outer membrane efflux protein; SPTR: Outer membrane efflux protein; PFAM: Outer membrane efflux protein YP_004160484.1 COGs: COG3696 silver efflux pump; InterPro IPR001036: IPR004763; KEGG: pgn:PGN_2013 cation efflux system protein; PFAM: acriflavin resistance protein; SPTR: Cation efflux system protein; TIGRFAM: heavy metal efflux pump, CzcA family; PFAM: AcrB/AcrD/AcrF family; TIGRFAM: heavy metal efflux pump (cobalt-zinc-cadmium) YP_004160485.1 COGs: COG0845 Membrane-fusion protein; InterPro IPR006143; KEGG: bfs:BF2153 lipoprotein; PFAM: hemolysin D; SPTR: Cation efflux system protein; TIGRFAM: efflux transporter, RND family, MFP subunit; TIGRFAM: RND family efflux transporter, MFP subunit YP_004160486.1 InterPro IPR000326; KEGG: fjo:Fjoh_1969 phosphoesterase, PA-phosphatase related; PFAM: phosphoesterase PA-phosphatase related; SMART: phosphoesterase PA-phosphatase related; SPTR: uncharacterized protein; PFAM: PAP2 superfamily YP_004160487.1 KEGG: pop:POPTR_591443 hypothetical protein YP_004160488.1 KEGG: bfs:BF2151 hypothetical protein; SPTR: uncharacterized protein; manually curated YP_004160489.1 COGs: COG1230 Co/Zn/Cd efflux system component; InterPro IPR002524; KEGG: pgn:PGN_0886 cation efflux protein; PFAM: cation efflux protein; SPTR: Heavy metal efflux pump, CzcD family; TIGRFAM: cation diffusion facilitator family transporter; PFAM: Cation efflux family; TIGRFAM: cation diffusion facilitator family transporter YP_004160490.1 COGs: COG0735 Fe2+/Zn2+ uptake regulation protein; KEGG: bfs:BF1284 hypothetical protein; SPTR: uncharacterized protein; PFAM: Ferric uptake regulator family YP_004160491.1 COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR000005: IPR018060; KEGG: bth:BT_1123 transcriptional regulator; PFAM: helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: uncharacterized protein; PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family YP_004160492.1 KEGG: bth:BT_1114 hypothetical protein; SPTR: uncharacterized protein YP_004160493.1 COGs: COG2814 Arabinose efflux permease; InterPro IPR011701; KEGG: lsa:LSA0227 drug:H(+) antiporter; PFAM: major facilitator superfamily MFS_1; SPTR: uncharacterized protein; PFAM: Major Facilitator Superfamily YP_004160494.1 COGs: COG0656 Aldo/keto reductase related to diketogulonate reductase; InterPro IPR020471: IPR001395: IPR018170; KEGG: bhy:BHWA1_00281 oxidoreductase, aldo/keto reductase; PFAM: aldo/keto reductase; SPTR: uncharacterized protein; PFAM: Aldo/keto reductase YP_004160496.1 COGs: COG0010 arginase/agmatinase/formimionoglutamate hydrolase arginase; InterPro IPR005924: IPR006035; KEGG: bpo:BP951000_0803 arginase; PFAM: arginase/agmatinase/formiminoglutamase; SPTR: arginase; PFAM: arginase YP_004160497.1 COGs: COG0778 Nitroreductase; InterPro IPR000415; KEGG: fnu:FN1223 dihydropteridine reductase; PFAM: nitroreductase; SPTR: uncharacterized protein; PFAM: Nitroreductase YP_004160498.1 COGs: COG1733 transcriptional regulator protein; InterPro IPR002577; KEGG: cpi:Cpin_5668 HxlR family transcriptional regulator; PFAM: helix-turn-helix HxlR type; SPTR: uncharacterized protein; PFAM: HxlR-like helix-turn-helix YP_004160499.1 InterPro IPR001668: IPR020062; KEGG: bvu:BVU_2464 mobilization protein; PFAM: plasmid recombination protein; SPTR: Mobilization protein BmpH; PFAM: Plasmid recombination enzyme YP_004160500.1 KEGG: pdi:BDI_2142 mobilization protein; SPTR: Mobilization protein YP_004160501.1 COGs: COG0858 Ribosome-binding factor A; InterPro IPR000238; KEGG: bth:BT_2839 ribosome-binding factor A; PFAM: ribosome-binding factor A; SPTR: uncharacterized protein; TIGRFAM: ribosome-binding factor A; PFAM: Ribosome-binding factor A; TIGRFAM: ribosome-binding factor A YP_004160502.1 COGs: COG4591 ABC-type transport system involved in lipoprotein release permease component; InterPro IPR003838; KEGG: bth:BT_2838 hypothetical protein; PFAM: protein of unknown function DUF214; SPTR: uncharacterized protein; PFAM: Predicted permease YP_004160503.1 KEGG: bth:BT_2796 hypothetical protein; SPTR: uncharacterized protein; PFAM: Bacterial membrane protein YfhO YP_004160504.1 COGs: COG0775 Nucleoside phosphorylase; InterPro IPR000845: IPR010049; KEGG: bvu:BVU_0894 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; PFAM: purine or other phosphorylase 1; PRIAM: Adenosylhomocysteine nucleosidase; SPTR: uncharacterized protein; TIGRFAM: MTA/SAH nucleosidase; PFAM: phosphorylase superfamily; TIGRFAM: 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase YP_004160505.1 COGs: COG1854 LuxS protein involved in autoinducer AI2 synthesis; InterPro IPR003815; KEGG: bvu:BVU_0895 S-ribosylhomocysteinase; PFAM: LuxS protein; PRIAM: S-ribosylhomocysteine lyase; SPTR: S-ribosylhomocysteine lyase; PFAM: S-Ribosylhomocysteinase (LuxS) YP_004160506.1 COGs: COG0318 Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterPro IPR000873: IPR020845; KEGG: bth:BT_2782 AMP-binding domain protein; PFAM: AMP-dependent synthetase and ligase; SPTR: uncharacterized protein; PFAM: AMP-binding enzyme YP_004160507.1 InterPro IPR001387: IPR013096; KEGG: bth:BT_2783 transcriptional regulator; PFAM: hypothetical protein; cupin; SMART: hypothetical protein; SPTR: uncharacterized protein; PFAM: Cupin domain; Helix-turn-helix YP_004160508.1 InterPro IPR001387; KEGG: pru:PRU_1496 hypothetical protein; SMART: hypothetical protein; SPTR: uncharacterized protein; PFAM: Bacterial regulatory proteins, lacI family YP_004160509.1 InterPro IPR001387: IPR017507; KEGG: bvu:BVU_3695 DNA-binding protein; PFAM: hypothetical protein; SMART: hypothetical protein; SPTR: Conserved domain protein; TIGRFAM: transcriptional regulator, y4mF family; PFAM: Helix-turn-helix; TIGRFAM: transcriptional regulator, y4mF family YP_004160510.1 InterPro IPR017508; KEGG: bvu:BVU_3694 hypothetical protein; SPTR: uncharacterized protein; TIGRFAM: HipA N-terminal domain protein; TIGRFAM: HipA N-terminal domain YP_004160511.1 COGs: COG3550 conserved hypothetical protein; InterPro IPR012894: IPR012893: IPR002057; KEGG: bvu:BVU_3693 hypothetical protein; PFAM: HipA domain protein; SPTR: Toxin-antitoxin system, toxin component, HipA family; PFAM: HipA-like N-terminal domain; HipA-like C-terminal domain YP_004160512.1 COGs: COG1917 conserved hypothetical protein contains double-stranded beta-helix domain; InterPro IPR003779; KEGG: msu:MS2158 hypothetical protein; PFAM: Carboxymuconolactone decarboxylase; SPTR: uncharacterized protein; PFAM: Cupin domain; Carboxymuconolactone decarboxylase YP_004160513.1 COGs: COG0184 Ribosomal protein S15P/S13E; InterPro IPR000589: IPR005290; KEGG: bfs:BF4259 30S ribosomal protein S15; PFAM: ribosomal protein S15; SPTR: 30S ribosomal protein S15; TIGRFAM: ribosomal protein S15; PFAM: Ribosomal protein S15; TIGRFAM: ribosomal protein S15, bacterial/organelle YP_004160514.1 COGs: COG1217 membrane GTPase involved in stress response; InterProIPR000795: IPR004161: IPR000640: IPR005225: IPR 006298; KEGG: bth:BT_2787 GTP-binding elongation factor family protein TypA/BipA; PFAM: protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; elongation factor G domain-containing protein; SPTR: GTP-binding protein TypA/BipA; TIGRFAM: GTP-binding protein TypA; small GTP-binding protein; PFAM: Elongation factor Tu domain 2; Elongation factor G C-terminus; Elongation factor Tu GTP binding domain; TIGRFAM: GTP-binding protein TypA/BipA; small GTP-binding protein domain YP_004160515.1 KEGG: bvu:BVU_0949 hypothetical protein; SPTR: uncharacterized protein YP_004160516.1 COGs: COG0778 Nitroreductase; InterPro IPR000415; KEGG: bvu:BVU_0975 NADH dehydrogenase/NAD(P)H nitroreductase; PFAM: nitroreductase; SPTR: uncharacterized protein; PFAM: Nitroreductase YP_004160517.1 COGs: COG1866 phosphoenolpyruvate carboxykinase (ATP); InterPro IPR001272: IPR015994; KEGG: bvu:BVU_0983 phosphoenolpyruvate carboxykinase; PFAM: phosphoenolpyruvate carboxykinase (ATP); SPTR: phosphoenolpyruvate carboxykinase [ATP]; TIGRFAM: phosphoenolpyruvate carboxykinase (ATP); PFAM: phosphoenolpyruvate carboxykinase; TIGRFAM: phosphoenolpyruvate carboxykinase (ATP) YP_004160518.1 COGs: COG0035 uracil phosphoribosyltransferase; KEGG: bvu:BVU_0984 uracil phosphoribosyltransferase; SPTR: uncharacterized protein; PFAM: phosphoribosyl transferase domain; TIGRFAM: uracil phosphoribosyltransferase YP_004160519.1 KEGG: bfs:BF3118 hypothetical protein; SPTR: uncharacterized protein YP_004160520.1 COGs: COG1696 membrane protein involved in D-alanine export; InterPro IPR004299; KEGG: bfs:BF3117 acetyltransferase membrane protein; PFAM: membrane bound O-acyl transferase MBOAT family protein; SPTR: uncharacterized protein; PFAM: MBOAT family YP_004160521.1 InterPro IPR009081; KEGG: bfs:BF3116 ACP; SPTR: ACP; PFAM: phosphopantetheine attachment site YP_004160522.1 COGs: COG1020 Non-ribosomal peptide synthetase modules and related protein; InterPro IPR000873: IPR020845; KEGG: bfr:BF3276 peptide synthetase; PFAM: AMP-dependent synthetase and ligase; SPTR: uncharacterized protein; PFAM: AMP-binding enzyme; TIGRFAM: amino acid adenylation domain YP_004160523.1 COGs: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase beta subunit; InterPro IPR011766; KEGG: bvu:BVU_0985 2-oxoglutarate ferredoxin oxidoreductase subunit beta; PFAM: thiamine pyrophosphate TPP-binding domain-containing protein; PRIAM: 2-oxoglutarate synthase; SPTR: uncharacterized protein; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP binding domain YP_004160524.1 COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterPro IPR002880; KEGG: bvu:BVU_0986 2-oxoglutarate synthase subunit KorA; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; SPTR: uncharacterized protein; PFAM: domain; Pyruvate ferredoxin/flavodoxin oxidoreductase; TIGRFAM: 2-oxoacid:acceptor oxidoreductase, alpha subunit YP_004160525.1 COGs: COG0342 Preprotein translocase subunit SecD; InterPro IPR003335: IPR005791: IPR005665; KEGG: bfr:BF4428 bifunctional preprotein translocase subunit SecD/SecF; PFAM: SecD/SecF/SecDF export membrane protein; SPTR: uncharacterized protein; TIGRFAM: protein-export membrane protein SecD; protein-export membrane protein, SecD/SecF family; protein-export membrane protein SecF; PFAM: Protein export membrane protein; SecD/SecF GG Motif; TIGRFAM: protein-export membrane protein SecD; protein-export membrane protein, SecD/SecF family; protein-export membrane protein SecF YP_004160526.1 COGs: COG0339 Zn-dependent oligopeptidase; InterPro IPR001567; KEGG: bth:BT_2834 peptidyl-dipeptidase; PFAM: peptidase M3A and M3B thimet/oligopeptidase F; PRIAM: peptidyl-dipeptidase Dcp; SPTR: uncharacterized protein; PFAM: peptidase M3 YP_004160527.1 InterPro IPR005135; KEGG: bfs:BF4223 hypothetical protein; PFAM: Endonuclease/exonuclease/phosphatase; SPTR: uncharacterized protein; PFAM: Endonuclease/Exonuclease/phosphatase YP_004160528.1 COGs: COG0705 membrane protein; InterPro IPR002610; KEGG: bfs:BF4222 transmembrane rhomboid family protein; PFAM: Rhomboid family protein; SPTR: uncharacterized protein; PFAM: Rhomboid family YP_004160529.1 COGs: COG0705 membrane protein; InterPro IPR002610; KEGG: bfs:BF4221 transmembrane rhomboid family protein; PFAM: Rhomboid family protein; SPTR: uncharacterized protein; PFAM: Rhomboid family YP_004160530.1 COGs: COG0776 Bacterial nucleoid DNA-binding protein; InterPro IPR000119: IPR020816: IPR017441; KEGG: bfs:BF4220 histone-like DNA-binding protein HU3; PFAM: histone family protein DNA-binding protein; SMART: histone family protein DNA-binding protein; SPTR: DNA-binding protein HU-beta; PFAM: Bacterial DNA-binding protein YP_004160531.1 COGs: COG0018 Arginyl-tRNA synthetase; InterProIPR001278: IPR005148: IPR015945: IPR008909: IPR 001412; KEGG: bfs:BF4219 arginyl-tRNA synthetase; PFAM: DALR anticodon binding domain protein; Arginyl-tRNA synthetase, class Ic, core; arginyl tRNA synthetase domain protein; PRIAM: Arginine--tRNA ligase; SPTR: Arginyl-tRNA synthetase; TIGRFAM: arginyl-tRNA synthetase; PFAM: DALR anticodon binding domain; Arginyl tRNA synthetase N terminal domain; tRNA synthetases class I (R); TIGRFAM: arginyl-tRNA synthetase YP_004160532.1 COGs: COG0550 Topoisomerase IA; InterProIPR006171: IPR013497: IPR006154: IPR003601: IPR 003602: IPR005733: IPR000380; KEGG: bfr:BF4419 DNA topoisomerase I; PFAM: DNA topoisomerase type IA central domain protein; TOPRIM domain-containing protein; PRIAM: DNA topoisomerase; SMART: DNA topoisomerase I DNA-binding; DNA topoisomerase I ATP-binding; Toprim sub domain-containing protein; SPTR: DNA topoisomerase; TIGRFAM: DNA topoisomerase I; PFAM: Toprim domain; DNA topoisomerase; TIGRFAM: DNA topoisomerase I, bacterial YP_004160533.1 KEGG: bth:BT_2817 TonB-dependent receptor; SPTR: uncharacterized protein YP_004160534.1 COGs: COG1729 conserved hypothetical protein; InterPro IPR019734: IPR013026: IPR001440; KEGG: bfs:BF4215 TPR repeat-containing protein; PFAM: hypothetical protein; SPTR: uncharacterized protein; PFAM: Tetratricopeptide repeat YP_004160535.1 COGs: COG1051 ADP-ribose pyrophosphatase; InterPro IPR000086: IPR020084; KEGG: bfs:BF4214 MutT/NUDIX family protein; PFAM: NUDIX hydrolase; SPTR: uncharacterized protein; PFAM: NUDIX domain YP_004160536.1 COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683; KEGG: cpi:Cpin_6559 oxidoreductase domain protein; PFAM: oxidoreductase domain protein; PRIAM: alpha-N-acetylgalactosaminidase; SPTR: uncharacterized protein; PFAM: Oxidoreductase, NAD-binding Rossmann fold YP_004160537.1 KEGG: bth:BT_0720 hypothetical protein; SPTR: uncharacterized protein YP_004160538.1 KEGG: cts:Ctha_2274 hypothetical protein; SPTR: uncharacterized protein YP_004160539.1 KEGG: cts:Ctha_2276 PEGA domain protein; SPTR: PEGA domain protein; PFAM: PEGA domain YP_004160540.1 KEGG: srm:SRM_02076 exonuclease SbcC; SPTR: Exonuclease SbcC YP_004160541.1 COGs: COG0847 DNA polymerase III epsilon subunit and related 3'-5' exonuclease; InterPro IPR013520: IPR006055; KEGG: bvu:BVU_3037 exonuclease/DNA polymerase III epsilon C; PFAM: Exonuclease RNase T and DNA polymerase III; SMART: Exonuclease; SPTR: uncharacterized protein; PFAM: Exonuclease YP_004160542.1 COGs: COG0483 fructose-1 6-bisphosphatase of inositol monophosphatase; InterPro IPR000760: IPR020583; KEGG: bfs:BF4187 inositol-1-monophosphatase; PFAM: inositol monophosphatase; SPTR: uncharacterized protein; PFAM: inositol monophosphatase YP_004160543.1 COGs: COG1040 amidophosphoribosyltransferase; InterPro IPR000836: IPR016160; KEGG: bth:BT_2800 amidophosphoribosyl-transferase; PFAM: phosphoribosyltransferase; SPTR: uncharacterized protein; manually curated; PFAM: phosphoribosyl transferase domain; TIGRFAM: comF family protein YP_004160544.1 COGs: COG0524 Sugar kinase ribokinase; InterPro IPR011611: IPR002173; KEGG: bth:BT_2799 PfkB family carbohydrate kinase; PFAM: PfkB domain protein; SPTR: uncharacterized protein; PFAM: pfkB family carbohydrate kinase YP_004160545.1 COGs: COG0793 Periplasmic protease; InterPro IPR001478: IPR005151: IPR004447; KEGG: bth:BT_2798 carboxy-terminal processing protease precursor; PFAM: peptidase S41; PDZ/DHR/GLGF domain protein; SMART: peptidase S41; PDZ/DHR/GLGF domain protein; SPTR: uncharacterized protein; TIGRFAM: carboxyl-terminal protease; PFAM: peptidase S41; PDZ domain (Also known as DHR or GLGF); TIGRFAM: C-terminal peptidase (prc) YP_004160546.1 COGs: COG0821 Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis; InterPro IPR004588: IPR017178; KEGG: bfs:BF4164 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; PFAM: IspG family protein; SPTR: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; TIGRFAM: 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase; PFAM: GcpE protein; TIGRFAM: 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase YP_004160547.1 COGs: COG0041 phosphoribosylcarboxyaminoimidazole (NCAIR) mutase; InterPro IPR000031; KEGG: bth:BT_2518 phosphoribosylaminoimidazole carboxylase; PFAM: 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase; PRIAM: phosphoribosylaminoimidazole carboxylase; SPTR: uncharacterized protein; TIGRFAM: phosphoribosylaminoimidazole carboxylase, catalytic subunit; PFAM: AIR carboxylase; TIGRFAM: phosphoribosylaminoimidazole carboxylase, PurE protein YP_004160548.1 COGs: COG0509 glycine cleavage system H protein (lipoate-binding); InterPro IPR002930: IPR017453: IPR003016; KEGG: bvu:BVU_1417 glycine cleavage system protein H; PFAM: glycine cleavage H-protein; SPTR: glycine cleavage system H protein; TIGRFAM: glycine cleavage system H protein; PFAM: glycine cleavage H-protein; TIGRFAM: glycine cleavage system H protein YP_004160549.1 KEGG: bfs:BF4161 transmembrane protein; SPTR: uncharacterized protein; PFAM: PAP2 superfamily YP_004160550.1 COGs: COG1508 DNA-directed RNA polymerase specialized sigma subunit sigma54 homolog; InterPro IPR000394: IPR007046: IPR007634; KEGG: bfr:BF4361 RNA polymerase sigma-54; PFAM: sigma-54 DNA-binding domain protein; sigma-54 factor core-binding region; SPTR: uncharacterized protein; TIGRFAM: RNA polymerase sigma-54 factor, RpoN; PFAM: Sigma-54 factor, Activator interacting domain (AID); Sigma-54 factor, core binding domain; Sigma-54, DNA binding domain; TIGRFAM: RNA polymerase sigma-54 factor YP_004160551.1 COGs: COG3119 Arylsulfatase A; InterPro IPR000917; KEGG: bvu:BVU_1160 arylsulfatase precursor; PFAM: sulfatase; SPTR: Arylsulfatase; PFAM: Sulfatase YP_004160552.1 COGs: COG0006 Xaa-Pro aminopeptidase; InterPro IPR000994; KEGG: bth:BT_2522 Xaa-Pro aminopeptidase; PFAM: peptidase M24; SPTR: uncharacterized protein; PFAM: Aminopeptidase P, N-terminal domain; Metallopeptidase M24 YP_004160554.1 InterPro IPR017936: IPR013740; KEGG: sli:Slin_0780 redoxin domain protein; PFAM: Redoxin domain protein; SPTR: uncharacterized protein; PFAM: Redoxin YP_004160555.1 KEGG: xtr:496660 keratin 24; SPTR: Keratin 13 YP_004160556.1 KEGG: bth:BT_3571 hypothetical protein; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF3244) YP_004160557.1 InterPro IPR013026: IPR019734; KEGG: bth:BT_2223 TPR repeat-containing protein; SPTR: uncharacterized protein YP_004160558.1 InterPro IPR018631: IPR012547; KEGG: bth:BT_4293 hypothetical protein; PFAM: AAA-ATPase-like; protein of unknown function DUF1703; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF1703); Predicted AAA-ATPase YP_004160559.1 COGs: COG0642 Signal transduction histidine kinase; InterPro IPR005467: IPR003594: IPR004358; KEGG: bfs:BF4153 two-component regulator sensor histidine kinase transcriptional regulator; PFAM: ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; SPTR: uncharacterized protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase YP_004160560.1 COGs: COG0572 Uridine kinase; KEGG: bfr:BF4352 uridine kinase; SPTR: Uridine kinase; PFAM: phosphoribulokinase / Uridine kinase YP_004160561.1 COGs: COG1283 Na+/phosphate symporter; InterPro IPR003841: IPR008170: IPR004633; KEGG: bth:BT_2528 Na+-dependent phosphate transporter; PFAM: Na+/Picotransporter; PhoU family protein; SPTR: uncharacterized protein; TIGRFAM: Na/Pi-cotransporter II-related protein; PFAM: PhoU domain; Na+/Pi-cotransporter; TIGRFAM: Na/Pi-cotransporter YP_004160562.1 COGs: COG1773 Rubredoxin; InterPro IPR004039: IPR001052: IPR018527; KEGG: bth:BT_2539 rubredoxin; PFAM: Rubredoxin-type Fe(Cys)4 protein; SPTR: Ferric-chelate reductase / Rubredoxin; PFAM: Rubredoxin YP_004160563.1 COGs: COG0642 Signal transduction histidine kinase; InterPro IPR005467: IPR003661: IPR003594: IPR004358; KEGG: bfs:BF4150 two-component system sensor kinase/response regulator fusion protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: uncharacterized protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain YP_004160564.1 COGs: COG0463 glycosyltransferase involved in cell wall biogenesis; InterPro IPR001173; KEGG: bfs:BF3262 glycosyl transferase; PFAM: glycosyl transferase 2; SPTR: Dolichol-phosphate mannosyltransferase; PFAM: glycosyl transferase 2 YP_004160565.1 COGs: COG3952 membrane protein; InterPro IPR011499; KEGG: bfs:BF3261 transport-related, membrane protein; PFAM: lipid A biosynthesis domain protein; SPTR: uncharacterized protein; PFAM: Lipid A Biosynthesis N-terminal domain YP_004160566.1 COGs: COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferase of PMT family; InterPro IPR003342; KEGG: bfr:BF3441 dolichyl-phosphate-mannose-protein mannosyltransferase; PFAM: glycosyl transferase 39; SPTR: Dolichyl-phosphate-mannose-protein mannosyltransferase; PFAM: Dolichyl-phosphate-mannose-protein mannosyltransferase YP_004160567.1 COGs: COG0451 Nucleoside-diphosphate-sugar epimerase; InterPro IPR001509: IPR008089; KEGG: bfs:BF3259 UDP-glucuronic acid epimerase; PFAM: NAD-dependent epimerase/dehydratase; SPTR: UDP-glucuronate 5'-epimerase; PFAM: NAD dependent epimerase/dehydratase YP_004160568.1 COGs: COG0474 Cation transport ATPase; InterProIPR004014: IPR008250: IPR005834: IPR006068: IPR 006408: IPR001757: IPR000695: IPR018303; KEGG: bfs:BF4149 transmembrane calcium-transporting ATPase; PFAM: E1-E2 ATPase-associated domain protein; cation transporting ATPase domain protein; Haloacid dehalogenase domain protein hydrolase; SPTR: Calcium-translocating P-type ATPase, PMCA-type; TIGRFAM: calcium-translocating P-type ATPase, PMCA-type; ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase; Cation transporting ATPase, C-terminus; Cation transporter/ATPase, N-terminus; haloacid dehalogenase-like hydrolase; TIGRFAM: plasma-membrane calcium-translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC YP_004160569.1 COGs: COG1011 hydrolase (HAD superfamily); InterPro IPR005834: IPR006402: IPR005833; KEGG: bfs:BF4148 haloacid dehalogenase-type hydrolase; PFAM: Haloacid dehalogenase domain protein hydrolase; SPTR: uncharacterized protein; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED YP_004160570.1 COGs: COG0196 FAD synthase; InterPro IPR015864: IPR015865: IPR002606; KEGG: bth:BT_2543 riboflavin biosynthesis protein RibF, riboflavin kinase; PFAM: Riboflavin kinase; FAD synthetase; SPTR: uncharacterized protein; TIGRFAM: riboflavin biosynthesis protein RibF; PFAM: Riboflavin kinase; FAD synthetase; TIGRFAM: riboflavin kinase/FMN adenylyltransferase YP_004160571.1 KEGG: bth:BT_2500 hypothetical protein; SPTR: uncharacterized protein YP_004160572.1 InterPro IPR003675; KEGG: bth:BT_2544 metal-dependent membrane protease; PFAM: Abortive infection protein; SPTR: uncharacterized protein; PFAM: CAAX amino terminal protease YP_004160573.1 KEGG: bfs:BF4144 transmembrane protein; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF2975) YP_004160574.1 KEGG: bfs:BF4144 transmembrane protein; SPTR: uncharacterized protein YP_004160575.1 KEGG: bvu:BVU_1295 hypothetical protein; SPTR: uncharacterized protein YP_004160576.1 KEGG: llk:LLKF_0558 TpsO family regulatory protein; SPTR: uncharacterized protein YP_004160577.1 COGs: COG3655 transcriptional regulator protein; InterPro IPR001387; KEGG: bfs:BF4143 DNA-binding protein; PFAM: hypothetical protein; SMART: hypothetical protein; SPTR: uncharacterized protein; PFAM: Helix-turn-helix YP_004160578.1 COGs: COG2166 SufE protein probably involved in Fe-S center assembly; InterPro IPR003808; KEGG: bth:BT_2547 hypothetical protein; PFAM: Fe-S metabolism associated SufE; SPTR: Fe-S metabolism associated domain family protein; PFAM: Fe-S metabolism associated domain YP_004160579.1 COGs: COG2234 aminopeptidase; InterPro IPR007484; KEGG: bvu:BVU_1317 leucine aminopeptidase precursor; PFAM: peptidase M28; SPTR: Leucine aminopeptidase; PFAM: peptidase M28 YP_004160580.1 COGs: COG1619 conserved hypothetical protein; InterPro IPR003507; KEGG: bth:BT_2549 carboxypeptidase; PFAM: peptidase U61 LD-carboxypeptidase A; SPTR: uncharacterized protein; PFAM: LD-carboxypeptidase YP_004160581.1 COGs: COG0280 phosphotransacetylase; InterPro IPR002505: IPR012147; KEGG: bfs:BF4138 phosphate acetyl/butyryltransferase; PFAM: phosphate acetyl/butaryl transferase; PRIAM: phosphate butyryltransferase; SPTR: uncharacterized protein; PFAM: phosphate acetyl/butaryl transferase YP_004160582.1 COGs: COG3426 Butyrate kinase; InterPro IPR000890: IPR011245; KEGG: bfr:BF4336 butyrate kinase; PFAM: acetate and butyrate kinase; SPTR: uncharacterized protein; TIGRFAM: butyrate kinase; PFAM: Acetokinase; TIGRFAM: butyrate kinase YP_004160583.1 COGs: COG1185 polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase); InterProIPR004088: IPR003029: IPR012162: IPR001247: IPR 015847: IPR015848: IPR018111: IPR004087; KEGG: bth:BT_2563 polynucleotide phosphorylase/polyadenylase; PFAM: 3' exoribonuclease; Exoribonuclease, phosphorolytic domain 2; polynucleotide phosphorylase, phosphorolytic RNA-binding; K Homology, type 1, subgroup; RNA binding S1 domain protein; PRIAM: polyribonucleotide nucleotidyltransferase; SMART: KH domain protein; SPTR: polyribonucleotide nucleotidyltransferase; TIGRFAM: polyribonucleotide nucleotidyltransferase; PFAM: KH domain; S1 RNA binding domain; 3' exoribonuclease, domain 1; 3' exoribonuclease, domain 2; polyribonucleotide nucleotidyltransferase, RNA binding domain; TIGRFAM: polyribonucleotide nucleotidyltransferase YP_004160584.1 InterPro IPR017936: IPR000866: IPR010916; KEGG: bfs:BF4128 hypothetical protein; PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; SPTR: uncharacterized protein; PFAM: AhpC/TSA family YP_004160585.1 COGs: COG0782 Transcription elongation factor; InterPro IPR001437: IPR006359: IPR018151; KEGG: bfs:BF4127 transcription elongation factor; PFAM: transcription elongation factor GreA/GreB domain-containing protein; SPTR: Transcription elongation factor; TIGRFAM: transcription elongation factor GreA; PFAM: domain; Transcription elongation factor, GreA/GreB, C-term; TIGRFAM: transcription elongation factor GreA YP_004160586.1 COGs: COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolase; InterPro IPR001310; KEGG: bth:BT_2566 HIT family protein; PFAM: histidine triad (HIT) protein; SPTR: uncharacterized protein; PFAM: HIT domain YP_004160587.1 COGs: COG0836 Mannose-1-phosphate guanylyltransferase; InterPro IPR005835; KEGG: bfs:BF4125 mannose-1-phosphate guanylyltransferase; PFAM: Nucleotidyl transferase; PRIAM: Mannose-1-phosphate guanylyltransferase; SPTR: uncharacterized protein; PFAM: Nucleotidyl transferase; TIGRFAM: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase YP_004160588.1 InterPro IPR003812; KEGG: bfr:BF4314 hypothetical protein; PFAM: filamentation induced by cAMP protein Fic; SPTR: uncharacterized protein; PFAM: Fic/DOC family YP_004160589.1 KEGG: dsy:DSY2015 hypothetical protein; SPTR: uncharacterized protein YP_004160590.1 COGs: COG1902 NADH:flavin oxidoreductase Old Yellow Enzyme family; InterPro IPR001155; KEGG: cpf:CPF_0697 oxidoreductase, FAD/FMN-binding; PFAM: NADH:flavin oxidoreductase/NADH oxidase; SPTR: uncharacterized protein; PFAM: NADH:flavin oxidoreductase / NADH oxidase YP_004160591.1 COGs: COG1733 transcriptional regulator protein; InterPro IPR002577; KEGG: cpi:Cpin_5668 HxlR family transcriptional regulator; PFAM: helix-turn-helix HxlR type; SPTR: uncharacterized protein; PFAM: HxlR-like helix-turn-helix YP_004160592.1 COGs: COG2249 NADPH-quinone reductase (modulator of drug activity B); InterPro IPR003680; KEGG: bth:BT_0673 NADP(H) oxidoreductase; PFAM: NAD(P)H dehydrogenase (quinone); SPTR: uncharacterized protein; PFAM: Flavodoxin-like fold YP_004160593.1 KEGG: bde:BDP_1620 hypothetical protein; SPTR: uncharacterized protein YP_004160594.1 COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR018060: IPR000005: IPR020449; KEGG: cpi:Cpin_5975 AraC family transcriptional regulator; PFAM: helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: AraC family transcriptional regulator; PFAM: AraC-like ligand binding domain; Bacterial regulatory helix-turn-helix proteins, AraC family YP_004160595.1 COGs: COG0778 Nitroreductase; InterPro IPR000415; KEGG: bvu:BVU_2535 NADH dehydrogenase/NAD(P)H nitroreductase; PFAM: nitroreductase; SPTR: uncharacterized protein; PFAM: Nitroreductase YP_004160596.1 COGs: COG1733 transcriptional regulator protein; InterPro IPR002577; KEGG: clj:CLJU_c14890 transcriptional regulator; PFAM: helix-turn-helix HxlR type; SPTR: HxlR family transcriptional regulator; PFAM: HxlR-like helix-turn-helix YP_004160597.1 COGs: COG5000 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation; InterPro IPR005467: IPR003594: IPR004358; KEGG: bth:BT_1470 two-component system sensor histidine kinase; PFAM: ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; SPTR: uncharacterized protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase YP_004160598.1 COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterProIPR002078: IPR001789: IPR002197: IPR003593: IPR 020441; KEGG: bth:BT_1469 two-component system response regulator; PFAM: sigma-54 factor interaction domain-containing protein; response regulator receiver; helix-turn-helix Fis-type; SMART: response regulator receiver; AAA ATPase; SPTR: uncharacterized protein; PFAM: Response regulator receiver domain; Bacterial regulatory protein, Fis family; Sigma-54 interaction domain YP_004160599.1 COGs: COG1538 Outer membrane protein; InterPro IPR003423; KEGG: bth:BT_1468 outer membrane efflux protein; PFAM: outer membrane efflux protein; SPTR: Outer membrane efflux protein; PFAM: Outer membrane efflux protein YP_004160600.1 COGs: COG1566 Multidrug resistance efflux pump; InterPro IPR006143; KEGG: bth:BT_1467 ABC transporter permease; PFAM: hemolysin D; SPTR: ABC transporter permease; TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: HlyD family secretion protein; TIGRFAM: RND family efflux transporter, MFP subunit YP_004160601.1 COGs: COG1136 ABC-type antimicrobial peptide transport system ATPase component; InterPro IPR003439: IPR003593: IPR017871; KEGG: bth:BT_1466 ABC transporter ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC transporter, ATP-binding protein; PFAM: ABC transporter YP_004160602.1 InterPro IPR003838; KEGG: bth:BT_1465 ABC transporter permease; PFAM: protein of unknown function DUF214; SPTR: Efflux ABC transporter, permease; PFAM: Predicted permease YP_004160603.1 COGs: COG3507 Beta-xylosidase; InterPro IPR006710; KEGG: gym:GYMC10_4842 xylan 1,4-beta-xylosidase; PFAM: glycoside hydrolase 43; PRIAM: alpha-N-arabinofuranosidase; SPTR: uncharacterized protein; PFAM: glycosyl hydrolases family 43 YP_004160604.1 COGs: COG5206 glycosylphosphatidylinositol transamidase (GPIT) subunit GPI8; InterPro IPR001096; KEGG: pru:PRU_1476 C13 family peptidase; PFAM: peptidase C13, legumain asparaginyl peptidase; PRIAM: Legumain; SPTR: Legumain; PFAM: Receptor family ligand binding region; peptidase C13 family YP_004160605.1 COGs: COG1744 Uncharacterized ABC-type transport system periplasmic component/surface lipoprotein; InterPro IPR003760; KEGG: pru:PRU_0514 hypothetical protein; PFAM: basic membrane lipoprotein; SPTR: Predicted protein; PFAM: Basic membrane protein YP_004160606.1 InterPro IPR020864; KEGG: bfr:BF1634 hypothetical protein; PFAM: Membrane attack complex component/perforin (MACPF) domain; SPTR: uncharacterized protein; PFAM: MAC/Perforin domain YP_004160607.1 InterPro IPR020864: IPR020865; KEGG: pru:PRU_0857 surface protein; PFAM: Membrane attack complex component/perforin (MACPF) domain; SMART: Membrane attack complex component/perforin (MACPF) domain, metazoa; SPTR: Ubiquitin family protein; PFAM: MAC/Perforin domain YP_004160608.1 InterPro IPR020864; KEGG: plu:plu1415 hypothetical protein; PFAM: Membrane attack complex component/perforin (MACPF) domain; SPTR: uncharacterized protein; PFAM: MAC/Perforin domain YP_004160609.1 KEGG: mmu:240028 leucyl/cystinyl aminopeptidase; SPTR: uncharacterized protein YP_004160610.1 KEGG: pto:PTO0878 glutamyl-tRNA synthetase; SPTR: uncharacterized protein YP_004160611.1 COGs: COG0642 Signal transduction histidine kinase; InterProIPR018060: IPR005467: IPR001789: IPR011110: IPR 011123: IPR003661: IPR003594: IPR000005: IPR004358: IPR018062:I PR005829; KEGG: bvu:BVU_2089 two-component system sensor histidine kinase/response regulator, hybrid; PFAM: ATP-binding region ATPase domain protein; two component regulator three Y domain-containing protein; two component regulator propeller; histidine kinase A domain protein; response regulator receiver; helix-turn-helix- domain containing protein AraC type; SMART: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; Helix-turn-helix, AraC domain; SPTR: uncharacterized protein; PFAM: Y_Y_Y domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; two component regulator propeller; His Kinase A (phosphoacceptor) domain; Bacterial regulatory helix-turn-helix proteins, AraC family YP_004160612.1 COGs: COG1501 alpha-glucosidase 31 of glycosyl hydrolase; InterPro IPR000322; KEGG: pdi:BDI_3102 alpha-glycosidase; PFAM: glycoside hydrolase 31; SPTR: uncharacterized protein; PFAM: glycosyl hydrolases family 31; PA14 domain YP_004160613.1 KEGG: bfs:BF4083 hypothetical protein; SPTR: uncharacterized protein YP_004160614.1 COGs: COG2096 conserved hypothetical protein; InterPro IPR002779: IPR017858; KEGG: bfs:BF4082 vitamin B12 related cobalamin adenosyltransferase; PFAM: cobalamin adenosyltransferase; PRIAM: Cob(I)yrinic acid a,c-diamide adenosyltransferase; SPTR: ATP:cob(I)alamin adenosyltransferase; TIGRFAM: ATP/cobalamin adenosyltransferase; PFAM: Cobalamin adenosyltransferase; TIGRFAM: ATP:cob(I)alamin adenosyltransferase YP_004160615.1 KEGG: bvu:BVU_1469 hypothetical protein; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF2795) YP_004160616.1 COGs: COG0514 Superfamily II DNA helicase; InterPro IPR014021: IPR001650: IPR011545: IPR014001; KEGG: bvu:BVU_2638 ATP-dependent DNA helicase; PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; SPTR: uncharacterized protein; PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase YP_004160617.1 KEGG: bth:BT_2410 acetyltransferase; SPTR: uncharacterized protein; manually curated YP_004160618.1 COGs: COG0698 Ribose 5-phosphate isomerase RpiB; InterPro IPR003500; KEGG: pmr:PMI2529 ribose 5-phosphate isomerase; PFAM: Ribose/galactose isomerase; SPTR: uncharacterized protein; TIGRFAM: sugar-phosphate isomerase, RpiB/LacA/LacB family; PFAM: Ribose/Galactose Isomerase; TIGRFAM: sugar-phosphate isomerases, RpiB/LacA/LacB family YP_004160619.1 COGs: COG2220 Zn-dependent hydrolase of the beta-lactamase fold; KEGG: dsa:Desal_0947 Zn-dependent hydrolase; SPTR: Zn-dependent hydrolase; PFAM: Metallo-beta-lactamase superfamily YP_004160620.1 InterPro IPR002781; KEGG: pat:Patl_2981 hypothetical protein; PFAM: protein of unknown function DUF81; SPTR: uncharacterized protein; PFAM: Sulfite exporter TauE/SafE YP_004160621.1 COGs: COG1979 Uncharacterized oxidoreductase Fe-dependent alcohol dehydrogenase; InterPro IPR001670; KEGG: cbe:Cbei_1932 iron-containing alcohol dehydrogenase; PFAM: iron-containing alcohol dehydrogenase; SPTR: uncharacterized protein; PFAM: Iron-containing alcohol dehydrogenase YP_004160622.1 COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR018060; KEGG: bfs:BF2137 AraC family transcriptional regulator; SMART: Helix-turn-helix, AraC domain; SPTR: uncharacterized protein; PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family YP_004160623.1 InterPro IPR018534; KEGG: bth:BT_0110 regulatory protein; PFAM: Tetracycline regulation of excision, RteC; SPTR: uncharacterized protein; PFAM: RteC protein YP_004160625.1 KEGG: bfs:BF4035 transmembrane protein; SPTR: uncharacterized protein YP_004160626.1 COGs: COG1198 Primosomal protein N' (replication factor Y) - superfamily II helicase; InterProIPR014021: IPR001650: IPR011545: IPR014001: IPR 005259; KEGG: bfs:BF4034 primosomal protein N'; PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; SPTR: uncharacterized protein; TIGRFAM: primosomal protein N'; manually curated; PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase; TIGRFAM: primosomal protein N' YP_004160627.1 COGs: COG0394 Protein-tyrosine-phosphatase; InterPro IPR017867: IPR000106; KEGG: bth:BT_2750 protein-tyrosine-phosphatase; PFAM: Protein-tyrosine phosphatase, low molecular weight; SMART: Protein-tyrosine phosphatase, low molecular weight; SPTR: uncharacterized protein; PFAM: Low molecular weight phosphotyrosine protein phosphatase YP_004160628.1 KEGG: fno:Fnod_1506 glucose-1-phosphate adenylyltransferase, GlgD subunit; SPTR: uncharacterized protein YP_004160629.1 COGs: COG1480 membrane-associated HD superfamily hydrolase; InterPro IPR011621: IPR006674: IPR003607: IPR006675; KEGG: bfs:BF4031 transmembrane HD family protein; PFAM: metal-dependent phosphohydrolase 7TM intracellular region; metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; SPTR: uncharacterized protein; TIGRFAM: metal dependent phophohydrolase; PFAM: 7TM-HD extracellular; HD domain; 7TM receptor with intracellular HD hydrolase; TIGRFAM: uncharacterized domain HDIG YP_004160630.1 COGs: COG0008 Glutamyl- and glutaminyl-tRNA synthetase; InterPro IPR020058: IPR004527: IPR020060: IPR001412; KEGG: bfs:BF4030 glutamyl-tRNA synthetase; PFAM: Glutamyl/glutaminyl-tRNA synthetase, class Ic, catalytic domain; SPTR: Glutamyl-tRNA synthetase; TIGRFAM: glutamyl-tRNA synthetase; PFAM: tRNA synthetases class I (E and Q), catalytic domain; TIGRFAM: glutamyl-tRNA synthetase, bacterial family YP_004160631.1 COGs: COG1519 3-deoxy-D-manno-octulosonic-acid transferase; InterPro IPR007507; KEGG: bfr:BF4205 3-deoxy-D-manno-octulosonic-acid transferase; PFAM: 3-deoxy-D-manno-octulosonic-acid transferase domain-containing protein; SPTR: uncharacterized protein; PFAM: 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) YP_004160632.1 KEGG: aag:AaeL_AAEL012551 hypothetical protein; SPTR: uncharacterized protein YP_004160633.1 COGs: COG0663 Carbonic anhydrase/acetyltransferase isoleucine patch superfamily; InterPro IPR001451; KEGG: bth:BT_2744 acetyltransferase; SPTR: uncharacterized protein YP_004160634.1 COGs: COG0006 Xaa-Pro aminopeptidase; InterPro IPR000587: IPR000994: IPR001969; KEGG: bfr:BF4203 aminopeptidase; PFAM: creatinase; peptidase M24; SPTR: uncharacterized protein; PFAM: Metallopeptidase M24; Creatinase/Prolidase N-terminal domain YP_004160635.1 InterPro IPR001911; KEGG: bfs:BF4025 30S ribosomal protein S21; PFAM: ribosomal protein S21; SPTR: 30S ribosomal protein S21; TIGRFAM: ribosomal protein S21; PFAM: Ribosomal protein S21; TIGRFAM: ribosomal protein S21 YP_004160636.1 COGs: COG4974 Site-specific recombinase XerD; InterPro IPR004107: IPR002104; KEGG: bfs:BF4024 site-specific recombinase; PFAM: integrase; integrase domain protein SAM domain protein; SPTR: uncharacterized protein; PFAM: Phage integrase, N-terminal SAM-like domain; Phage integrase; TIGRFAM: tyrosine recombinase XerC YP_004160637.1 InterPro IPR003489; KEGG: bfs:BF4023 sigma(54) modulation protein; PFAM: sigma 54 modulation protein/ribosomal protein S30EA; SPTR: Ribosomal subunit interface protein; TIGRFAM: ribosomal subunit interface protein; PFAM: Sigma 54 modulation protein / S30EA ribosomal protein; TIGRFAM: ribosomal subunit interface protein YP_004160638.1 COGs: COG0050 GTPase - translation elongation factors; InterProIPR000795: IPR004161: IPR004160: IPR004541: IPR 005225; KEGG: bfs:BF4022 elongation factor Tu; PFAM: protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; elongation factor Tu domain-containing protein; SPTR: Elongation factor Tu; TIGRFAM: translation elongation factor Tu; small GTP-binding protein; PFAM: Elongation factor Tu C-terminal domain; Elongation factor Tu domain 2; Elongation factor Tu GTP binding domain; TIGRFAM: small GTP-binding protein domain; translation elongation factor TU YP_004160639.1 InterPro IPR001901: IPR005807; KEGG: bfs:BF4021 preprotein translocase SecE subunit; PFAM: protein secE/sec61-gamma protein; SPTR: preprotein translocase subunit SecE; TIGRFAM: preprotein translocase subunit SecE; manually curated; PFAM: SecE/Sec61-gamma subunits of protein translocation complex; TIGRFAM: preprotein translocase subunit SecE, bacterial YP_004160640.1 COGs: COG0250 Transcription antiterminator; InterPro IPR006645: IPR005824: IPR001062; KEGG: bfs:BF4020 transcription antitermination protein; PFAM: NGN domain-containing protein; KOW domain protein; SMART: NGN domain-containing protein; KOW domain protein; SPTR: Transcription antitermination protein nusG; TIGRFAM: transcription termination/antitermination factor NusG; PFAM: Transcription termination factor nusG; KOW motif; TIGRFAM: transcription termination/antitermination factor NusG YP_004160641.1 COGs: COG0080 Ribosomal protein L11; InterProIPR020784: IPR020783: IPR000911: IPR006519: IPR 020785; KEGG: bfs:BF4019 50S ribosomal protein L11; PFAM: Ribosomal protein L11-like; SMART: ribosomal protein L11; SPTR: 50S ribosomal protein L11; TIGRFAM: ribosomal protein L11; PFAM: Ribosomal protein L11, RNA binding domain; Ribosomal protein L11, N-terminal domain; TIGRFAM: 50S ribosomal protein L11 YP_004160642.1 COGs: COG0081 Ribosomal protein L1; InterPro IPR002143: IPR005878; KEGG: bth:BT_2737 50S ribosomal protein L1; PFAM: ribosomal protein L1; SPTR: 50S ribosomal protein L1; TIGRFAM: ribosomal protein L1; PFAM: Ribosomal protein L1p/L10e family; TIGRFAM: ribosomal protein L1, bacterial/chloroplast YP_004160643.1 COGs: COG0244 Ribosomal protein L10; InterPro IPR001790; KEGG: bfr:BF4194 50S ribosomal protein L10; PFAM: ribosomal protein L10; SPTR: Predicted protein; PFAM: Ribosomal protein L10 YP_004160644.1 COGs: COG0222 Ribosomal protein L7/L12; InterPro IPR000206: IPR013823; KEGG: bvu:BVU_0814 50S ribosomal protein L7/L12; PFAM: Ribosomal protein L7/L12; SPTR: 50S ribosomal protein L7/L12; TIGRFAM: ribosomal protein L7/L12; PFAM: Ribosomal protein L7/L12 C-terminal domain; TIGRFAM: ribosomal protein L7/L12 YP_004160645.1 COGs: COG0085 DNA-directed RNA polymerase beta subunit/140 kD subunit; InterProIPR010243: IPR007644: IPR007642: IPR007645: IPR 019462: IPR007120: IPR007641: IPR007121; KEGG: bfs:BF4015 DNA-directed RNA polymerase subunit beta; PFAM: RNA polymerase Rpb2 domain 6; RNA polymerase Rpb2 domain 3; RNA polymerase Rpb2 domain 2; RNA polymerase beta subunit; DNA-directed RNA polymerase, beta subunit, external 1 domain; RNA polymerase Rpb2 domain 7; SPTR: DNA-directed RNA polymerase subunit beta; TIGRFAM: DNA-directed RNA polymerase, beta subunit; PFAM: RNA polymerase Rpb2, domain 3; RNA polymerase Rpb2, domain 6; RNA polymerase beta subunit; RNA polymerase beta subunit external 1 domain; RNA polymerase Rpb2, domain 2; RNA polymerase Rpb2, domain 7; TIGRFAM: DNA-directed RNA polymerase, beta subunit YP_004160646.1 COGs: COG0086 DNA-directed RNA polymerase beta' subunit/160 kD subunit; InterProIPR012754: IPR007080: IPR000722: IPR007066: IPR 007083: IPR007081: IPR006592; KEGG: bth:BT_2733 DNA-directed RNA polymerase subunit beta'; PFAM: RNA polymerase Rpb1 domain 1; RNA polymerase alpha subunit; RNA polymerase Rpb1 domain 3; RNA polymerase Rpb1 domain 4; RNA polymerase Rpb1 domain 5; SMART: RNA polymerase I subunit A domain protein; SPTR: DNA-directed RNA polymerase subunit beta'; TIGRFAM: DNA-directed RNA polymerase, beta' subunit; PFAM: RNA polymerase Rpb1, domain 2; RNA polymerase Rpb1, domain 4; RNA polymerase Rpb1, domain 1; RNA polymerase Rpb1, domain 3; RNA polymerase Rpb1, domain 5; TIGRFAM: DNA-directed RNA polymerase, beta' subunit, predominant form YP_004160647.1 KEGG: bth:BT_2732 hypothetical protein; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF3467) YP_004160648.1 COGs: COG0048 Ribosomal protein S12; InterPro IPR006032: IPR005679; KEGG: bfs:BF4007 30S ribosomal protein S12; PFAM: ribosomal protein S12/S23; SPTR: 30S ribosomal protein S12; TIGRFAM: ribosomal protein S12; PFAM: Ribosomal protein S12; TIGRFAM: ribosomal protein S12, bacterial/organelle YP_004160649.1 COGs: COG0049 Ribosomal protein S7; InterPro IPR000235: IPR005717; KEGG: bvu:BVU_0808 30S ribosomal protein S7; PFAM: ribosomal protein S7; SPTR: 30S ribosomal protein S7; TIGRFAM: ribosomal protein S7; PFAM: Ribosomal protein S7p/S5e; TIGRFAM: ribosomal protein S7, bacterial/organelle YP_004160650.1 COGs: COG0480 Translation elongation factors (GTPase); InterProIPR000795: IPR004161: IPR005517: IPR000640: IPR 004540: IPR005225; KEGG: bfs:BF4005 elongation factor G; PFAM: protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; elongation factor G domain IV; elongation factor G domain-containing protein; SPTR: uncharacterized protein; TIGRFAM: translation elongation factor G; small GTP-binding protein; PFAM: Elongation factor Tu domain 2; Elongation factor G C-terminus; Elongation factor Tu GTP binding domain; Elongation factor G, domain IV; TIGRFAM: translation elongation factor EF-G; small GTP-binding protein domain YP_004160651.1 COGs: COG0051 Ribosomal protein S10; InterPro IPR005731: IPR001848: IPR018268; KEGG: bvu:BVU_0806 30S ribosomal protein S10; PFAM: ribosomal protein S10; SPTR: 30S ribosomal protein S10; TIGRFAM: ribosomal protein S10; PFAM: Ribosomal protein S10p/S20e; TIGRFAM: ribosomal protein S10, bacterial/organelle YP_004160652.1 COGs: COG0087 Ribosomal protein L3; InterPro IPR000597: IPR019927: IPR019926; KEGG: bth:BT_2727 50S ribosomal protein L3; PFAM: ribosomal protein L3; SPTR: 50S ribosomal protein L3; TIGRFAM: 50S ribosomal protein L3; PFAM: Ribosomal protein L3; TIGRFAM: 50S ribosomal protein L3, bacterial YP_004160653.1 COGs: COG0088 Ribosomal protein L4; InterPro IPR002136; KEGG: bfs:BF4002 50S ribosomal protein L4; PFAM: ribosomal protein L4/L1e; SPTR: 50S ribosomal protein L4; PFAM: Ribosomal protein L4/L1 family YP_004160654.1 COGs: COG0089 Ribosomal protein L23; InterPro IPR013025; KEGG: bfs:BF4001 50S ribosomal protein L23; PFAM: Ribosomal protein L25/L23; SPTR: 50S ribosomal protein L23; PFAM: Ribosomal protein L23 YP_004160655.1 COGs: COG0090 Ribosomal protein L2; InterPro IPR002171: IPR005880; KEGG: bfs:BF4000 50S ribosomal protein L2; PFAM: ribosomal protein L2; SPTR: 50S ribosomal protein L2; TIGRFAM: ribosomal protein L2; PFAM: Ribosomal Proteins L2, RNA binding domain; Ribosomal Proteins L2, C-terminal domain; TIGRFAM: ribosomal protein L2, bacterial/organellar YP_004160656.1 COGs: COG0185 Ribosomal protein S19; InterPro IPR002222: IPR005732: IPR020934; KEGG: bvu:BVU_0801 30S ribosomal protein S19; PFAM: ribosomal protein S19/S15; SPTR: 30S ribosomal protein S19; TIGRFAM: ribosomal protein S19; PFAM: Ribosomal protein S19; TIGRFAM: ribosomal protein S19, bacterial/organelle YP_004160657.1 COGs: COG0091 Ribosomal protein L22; InterPro IPR001063: IPR005727; KEGG: bfr:BF4176 50S ribosomal protein L22; PFAM: ribosomal protein L22/L17; SPTR: 50S ribosomal protein L22; TIGRFAM: ribosomal protein L22; PFAM: Ribosomal protein L22p/L17e; TIGRFAM: ribosomal protein L22, bacterial type YP_004160658.1 COGs: COG0092 Ribosomal protein S3; InterProIPR004044: IPR008282: IPR001351: IPR004087: IPR 005704: IPR018280; KEGG: bth:BT_2721 30S ribosomal protein S3; PFAM: ribosomal protein S3- domain protein; Ribosomal protein S3 domain; KH type 2 domain protein; SMART: KH domain protein; SPTR: 30S ribosomal protein S3; TIGRFAM: ribosomal protein S3; PFAM: KH domain; Ribosomal protein S3, C-terminal domain; Ribosomal protein S3, N-terminal domain; TIGRFAM: ribosomal protein S3, bacterial type YP_004160659.1 COGs: COG0197 Ribosomal protein L16/L10E; InterPro IPR000114: IPR016180: IPR020798; KEGG: bth:BT_2720 50S ribosomal protein L16; PFAM: Ribosomal protein L10e/L16; SPTR: Ribosomal protein L16; TIGRFAM: ribosomal protein L16; PFAM: Ribosomal protein L16p/L10e; TIGRFAM: ribosomal protein L16, bacterial/organelle YP_004160660.1 InterPro IPR001854: IPR018254; KEGG: bth:BT_2719 50S ribosomal protein L29; PFAM: ribosomal protein L29; SPTR: uncharacterized protein; TIGRFAM: ribosomal protein L29; PFAM: Ribosomal L29 protein; TIGRFAM: ribosomal protein L29 YP_004160661.1 COGs: COG0186 Ribosomal protein S17; InterPro IPR000266: IPR019984: IPR019979; KEGG: bvu:BVU_0796 30S ribosomal protein S17; PFAM: ribosomal protein S17; SPTR: 30S ribosomal protein S17; TIGRFAM: 30S ribosomal protein S17; PFAM: Ribosomal protein S17; TIGRFAM: 30S ribosomal protein S17 YP_004160662.1 COGs: COG0093 Ribosomal protein L14; InterPro IPR019972: IPR000218: IPR005745; KEGG: bvu:BVU_0795 50S ribosomal protein L14; PFAM: ribosomal protein L14b/L23e; SPTR: 50S ribosomal protein L14; TIGRFAM: ribosomal protein L14; PFAM: Ribosomal protein L14p/L23e; TIGRFAM: ribosomal protein L14, bacterial/organelle YP_004160663.1 COGs: COG0198 Ribosomal protein L24; InterPro IPR005824: IPR003256; KEGG: bfs:BF3992 50S ribosomal protein L24; PFAM: KOW domain protein; SMART: KOW domain protein; SPTR: 50S ribosomal protein L24; TIGRFAM: ribosomal protein L24; PFAM: KOW motif; TIGRFAM: ribosomal protein L24, bacterial/organelle YP_004160664.1 COGs: COG0094 Ribosomal protein L5; InterPro IPR002132; KEGG: bfs:BF3991 50S ribosomal protein L5; SPTR: 50S ribosomal protein L5; PFAM: ribosomal L5P family C-terminus; Ribosomal protein L5 YP_004160665.1 COGs: COG0199 Ribosomal protein S14; InterPro IPR001209: IPR018271; KEGG: bfs:BF3990 30S ribosomal protein S14; PFAM: ribosomal protein S14; SPTR: 30S ribosomal protein S14; PFAM: Ribosomal protein S14p/S29e YP_004160666.1 COGs: COG0096 Ribosomal protein S8; InterPro IPR000630; KEGG: bfs:BF3989 30S ribosomal protein S8; PFAM: ribosomal protein S8; SPTR: 30S ribosomal protein S8; PFAM: Ribosomal protein S8 YP_004160667.1 COGs: COG0097 Ribosomal protein L6P/L9E; InterPro IPR020040: IPR019906: IPR000702: IPR002358; KEGG: bfs:BF3988 50S ribosomal protein L6; PFAM: Ribosomal protein L6, alpha-beta domain; SPTR: 50S ribosomal protein L6; TIGRFAM: ribosomal protein L6; PFAM: Ribosomal protein L6; TIGRFAM: ribosomal protein L6, bacterial type YP_004160668.1 COGs: COG0256 Ribosomal protein L18; InterPro IPR005484: IPR004389; KEGG: bth:BT_2711 50S ribosomal protein L18; PFAM: ribosomal protein L18P/L5E; SPTR: 50S ribosomal protein L18; TIGRFAM: ribosomal protein L18; PFAM: Ribosomal L18p/L5e family; TIGRFAM: ribosomal protein L18, bacterial type YP_004160669.1 COGs: COG0098 Ribosomal protein S5; InterPro IPR005712: IPR013810: IPR018192: IPR005324; KEGG: bfs:BF3986 30S ribosomal protein S5; PFAM: ribosomal protein S5 domain protein; Ribosomal protein S5; SPTR: uncharacterized protein; TIGRFAM: ribosomal protein S5; PFAM: Ribosomal protein S5, N-terminal domain; Ribosomal protein S5, C-terminal domain; TIGRFAM: ribosomal protein S5, bacterial/organelle type YP_004160670.1 COGs: COG1841 Ribosomal protein L30/L7E; InterPro IPR000517: IPR005996; KEGG: bfs:BF3985 50S ribosomal protein L30; PFAM: ribosomal protein L30; SPTR: 50S ribosomal protein L30; TIGRFAM: ribosomal protein L30; PFAM: Ribosomal protein L30p/L7e; TIGRFAM: ribosomal protein L30, bacterial/organelle YP_004160671.1 COGs: COG0200 Ribosomal protein L15; InterPro IPR005749: IPR001196; KEGG: bfs:BF3984 50S ribosomal protein L15; SPTR: 50S ribosomal protein L15; TIGRFAM: ribosomal protein L15; PFAM: Ribosomal protein L18e/L15; TIGRFAM: ribosomal protein L15, bacterial/organelle YP_004160672.1 COGs: COG0201 Preprotein translocase subunit SecY; InterPro IPR002208: IPR019825; KEGG: bfs:BF3983 preprotein translocase subunit SecY; PFAM: SecY protein; SPTR: Preprotein translocase subunit SecY; TIGRFAM: preprotein translocase, SecY subunit; PFAM: eubacterial secY protein; TIGRFAM: preprotein translocase, SecY subunit YP_004160673.1 COGs: COG0024 methionine aminopeptidase; InterPro IPR000994: IPR002467: IPR001714; KEGG: bfs:BF3982 methionine aminopeptidase; PFAM: peptidase M24; SPTR: methionine aminopeptidase; TIGRFAM: methionine aminopeptidase, type I; PFAM: Metallopeptidase M24; TIGRFAM: methionine aminopeptidase, type I YP_004160674.1 COGs: COG0361 Translation initiation factor 1 (IF-1); InterPro IPR006196: IPR004368; KEGG: bfs:BF3981 translation initiation factor IF-1; PFAM: S1 IF1 family protein; SPTR: Translation initiation factor IF-1; TIGRFAM: translation initiation factor IF-1; PFAM: Translation initiation factor 1A / IF-1; TIGRFAM: translation initiation factor IF-1 YP_004160675.1 InterPro IPR000473; KEGG: bfs:BF3980 50S ribosomal protein L36; PFAM: ribosomal protein L36; SPTR: Ribosomal protein L36; TIGRFAM: ribosomal protein L36; PFAM: Ribosomal protein L36; TIGRFAM: ribosomal protein L36, bacterial type YP_004160676.1 COGs: COG0099 Ribosomal protein S13; InterPro IPR001892: IPR019980: IPR018269; KEGG: bth:BT_2704 30S ribosomal protein S13; PFAM: ribosomal protein S13; SPTR: 30S ribosomal protein S13; TIGRFAM: 30S ribosomal protein S13; PFAM: Ribosomal protein S13/S18; TIGRFAM: 30S ribosomal protein S13 YP_004160677.1 COGs: COG0100 Ribosomal protein S11; InterPro IPR001971: IPR019981: IPR018102; KEGG: bfs:BF3978 30S ribosomal protein S11; PFAM: ribosomal protein S11; SPTR: 30S ribosomal protein S11; TIGRFAM: 30S ribosomal protein S11; PFAM: Ribosomal protein S11; TIGRFAM: 30S ribosomal protein S11 YP_004160679.1 COGs: COG0522 Ribosomal protein S4 and related protein; InterPro IPR005709: IPR002942: IPR018079: IPR001912; KEGG: bth:BT_2702 30S ribosomal protein S4; PFAM: ribosomal protein S4; RNA-binding S4 domain protein; SMART: RNA-binding S4 domain protein; SPTR: 30S ribosomal protein S4; TIGRFAM: ribosomal protein S4; PFAM: Ribosomal protein S4/S9 N-terminal domain; S4 domain; TIGRFAM: ribosomal protein S4, bacterial/organelle type YP_004160680.1 COGs: COG0202 DNA-directed RNA polymerase alpha subunit/40 kD subunit; InterProIPR011773: IPR011261: IPR011262: IPR011260: IPR 011263; KEGG: bfs:BF3976 DNA-directed RNA polymerase subunit alpha; PFAM: RNA polymerase insert; RNA polymerase dimerisation; RNA polymerase alpha subunit domain protein; SMART: RNA polymerase RpoA/D/Rpb3-type; SPTR: uncharacterized protein; TIGRFAM: DNA-directed RNA polymerase, alpha subunit; PFAM: RNA polymerase Rpb3/Rpb11 dimerisation domain; RNA polymerase Rpb3/RpoA insert domain; Bacterial RNA polymerase, alpha chain C terminal domain; TIGRFAM: DNA-directed RNA polymerase, alpha subunit, bacterial and chloroplast-type YP_004160681.1 COGs: COG0203 Ribosomal protein L17; InterPro IPR000456; KEGG: bth:BT_2700 50S ribosomal protein L17; PFAM: ribosomal protein L17; SPTR: 50S ribosomal protein L17; TIGRFAM: ribosomal protein L17; PFAM: Ribosomal protein L17; TIGRFAM: ribosomal protein L17 YP_004160682.1 KEGG: bfs:BF3974 hypothetical protein; SPTR: uncharacterized protein YP_004160683.1 KEGG: bfs:BF3973 transmembrane protein; SPTR: uncharacterized protein YP_004160684.1 COGs: COG0249 Mismatch repair ATPase (MutS family); InterPro IPR000432; KEGG: bfr:BF4151 DNA mismatch repair protein MutS; PFAM: DNA mismatch repair protein MutS domain protein; SMART: DNA mismatch repair protein MutS domain protein; SPTR: uncharacterized protein; PFAM: MutS domain V; MutS domain III YP_004160685.1 KEGG: bfr:BF4149 hypothetical protein; SPTR: uncharacterized protein YP_004160686.1 COGs: COG2987 Urocanate hydratase; InterPro IPR000193; KEGG: bth:BT_2694 urocanate hydratase; PFAM: Urocanase; PRIAM: Urocanate hydratase; SPTR: uncharacterized protein; TIGRFAM: urocanate hydratase; manually curated; PFAM: Urocanase; TIGRFAM: urocanate hydratase YP_004160687.1 COGs: COG3643 Glutamate formiminotransferase; InterPro IPR012886: IPR013802: IPR004227; KEGG: bvu:BVU_0334 formiminotransferase-cyclodeaminase; PFAM: formiminotransferase domain protein; formiminotransferase domain protein; PRIAM: Glutamate formimidoyltransferase; SPTR: uncharacterized protein; TIGRFAM: glutamate formiminotransferase; PFAM: formiminotransferase domain, N-terminal subdomain; formiminotransferase domain; TIGRFAM: glutamate formiminotransferase YP_004160688.1 COGs: COG1228 Imidazolonepropionase and related amidohydrolase; InterPro IPR005920: IPR006680; KEGG: bth:BT_2692 imidazolonepropionase; PFAM: amidohydrolase; PRIAM: Imidazolonepropionase; SPTR: Imidazolonepropionase; TIGRFAM: imidazolonepropionase; PFAM: Amidohydrolase; TIGRFAM: imidazolonepropionase YP_004160689.1 COGs: COG3404 methenyl tetrahydrofolate cyclohydrolase; InterPro IPR007044; KEGG: bfs:BF3967 formiminotransferase-cyclodeaminase; PFAM: formiminotransferase-cyclodeaminase; SPTR: uncharacterized protein; PFAM: formiminotransferase-cyclodeaminase YP_004160690.1 COGs: COG2986 Histidine ammonia-lyase; InterPro IPR001106: IPR005921; KEGG: bfs:BF3966 histidine ammonia-lyase; PFAM: phenylalanine/histidine ammonia-lyase; PRIAM: Histidine ammonia-lyase; SPTR: Histidine ammonia-lyase; TIGRFAM: histidine ammonia-lyase; PFAM: Phenylalanine and histidine ammonia-lyase; TIGRFAM: histidine ammonia-lyase YP_004160691.1 InterPro IPR001647; KEGG: bfs:BF3965 TetR transcriptional regulator; PFAM: regulatory protein TetR; SPTR: uncharacterized protein; PFAM: Bacterial regulatory proteins, tetR family YP_004160692.1 COGs: COG1538 Outer membrane protein; InterPro IPR003423; KEGG: bth:BT_2688 outer membrane efflux protein; PFAM: outer membrane efflux protein; SPTR: uncharacterized protein; PFAM: Outer membrane efflux protein YP_004160693.1 COGs: COG0845 Membrane-fusion protein; InterPro IPR006143; KEGG: bfs:BF3963 membrane fusion protein transporter; SPTR: uncharacterized protein; TIGRFAM: efflux transporter, RND family, MFP subunit; TIGRFAM: RND family efflux transporter, MFP subunit YP_004160694.1 COGs: COG0841 Cation/multidrug efflux pump; InterPro IPR001036; KEGG: bth:BT_2686 cation efflux transporter; PFAM: acriflavin resistance protein; SPTR: uncharacterized protein; PFAM: AcrB/AcrD/AcrF family; TIGRFAM: heavy metal efflux pump (cobalt-zinc-cadmium); The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family YP_004160695.1 KEGG: bth:BT_2685 hypothetical protein; SPTR: uncharacterized protein YP_004160696.1 KEGG: bfr:BF4138 periplasmic protein; SPTR: uncharacterized protein YP_004160697.1 KEGG: bth:BT_2682 periplasmic protein; SPTR: uncharacterized protein; manually curated YP_004160698.1 COGs: COG1696 membrane protein involved in D-alanine export; InterPro IPR004299; KEGG: bth:BT_2681 alginate O-acetylation protein; PFAM: membrane bound O-acyl transferase MBOAT family protein; SPTR: uncharacterized protein; PFAM: MBOAT family YP_004160699.1 KEGG: bfs:BF3948 hypothetical protein; SPTR: uncharacterized protein YP_004160700.1 COGs: COG0811 Biopolymer transport protein; InterPro IPR002898; KEGG: bfs:BF3947 transmembrane MotA/TolQ/ExbB proton channel family protein; PFAM: MotA/TolQ/ExbB proton channel; SPTR: uncharacterized protein; PFAM: MotA/TolQ/ExbB proton channel family; TC 2.C.1.1.1 YP_004160701.1 InterPro IPR003400; KEGG: bfs:BF3946 hypothetical protein; PFAM: Biopolymer transport protein ExbD/TolR; SPTR: uncharacterized protein; manually curated; PFAM: Biopolymer transport protein ExbD/TolR; TC 2.C.1.1.1 YP_004160702.1 InterPro IPR003400; KEGG: bfs:BF3945 hypothetical protein; PFAM: Biopolymer transport protein ExbD/TolR; SPTR: uncharacterized protein; PFAM: Biopolymer transport protein ExbD/TolR YP_004160703.1 InterPro IPR006260; KEGG: bfs:BF3944 TonB family outer membrane receptor protein; PFAM: TonB domain; SPTR: uncharacterized protein; TIGRFAM: TonB family protein; PFAM: Gram-negative bacterial tonB protein; TIGRFAM: TonB family C-terminal domain; TC 2.C.1.1.1 YP_004160704.1 COGs: COG0226 ABC-type phosphate transport system periplasmic component; KEGG: bfs:BF3943 hypothetical protein; SPTR: uncharacterized protein YP_004160705.1 InterPro IPR019734: IPR013026: IPR001440; KEGG: bfr:BF4129 TPR repeat-containing protein; PFAM: hypothetical protein; SPTR: uncharacterized protein YP_004160706.1 COGs: COG1131 ABC-type multidrug transport system ATPase component; InterPro IPR003439: IPR003593; KEGG: bfr:BF4128 ABC transporter ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: uncharacterized protein; PFAM: ABC transporter YP_004160707.1 KEGG: bfs:BF3940 transmembrane protein; SPTR: uncharacterized protein YP_004160708.1 COGs: COG1725 transcriptional regulator protein; InterPro IPR000524; KEGG: bfs:BF3939 GntR family transcriptional regulator; PFAM: regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; SPTR: uncharacterized protein; PFAM: Bacterial regulatory proteins, gntR family YP_004160709.1 KEGG: bfs:BF3938 hypothetical protein; SPTR: uncharacterized protein YP_004160710.1 InterPro IPR017936; KEGG: pru:PRU_2156 hypothetical protein; SPTR: uncharacterized protein; PFAM: Redoxin YP_004160711.1 InterPro IPR001647; KEGG: bfs:BF3933 TetR family transcriptional regulator; PFAM: regulatory protein TetR; SPTR: uncharacterized protein; PFAM: Bacterial regulatory proteins, tetR family YP_004160712.1 COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR002198: IPR011284: IPR002347: IPR020904; KEGG: bfs:BF3932 3-oxoacyl-[acyl-carrier protein] reductase; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: 3-oxoacyl-[acyl-carrier-protein] reductase; TIGRFAM: 3-oxoacyl-ACP reductase; PFAM: short chain dehydrogenase; TIGRFAM: 3-oxoacyl-ACP reductase YP_004160713.1 COGs: COG0564 Pseudouridylate synthase 23S RNA-specific; InterPro IPR006145; KEGG: bth:BT_3772 ribosomal large subunit pseudouridine synthase D; PFAM: pseudouridine synthase; SPTR: Pseudouridine synthase; PFAM: RNA pseudouridylate synthase; TIGRFAM: pseudouridine synthase, RluA family YP_004160714.1 COGs: COG1506 Dipeptidyl aminopeptidase/acylaminoacyl-peptidase; KEGG: bth:BT_1838 alanyl dipeptidyl peptidase; SPTR: uncharacterized protein; PFAM: Prolyl oligopeptidase YP_004160715.1 KEGG: bth:BT_3625 hypothetical protein; SPTR: uncharacterized protein YP_004160716.1 KEGG: bth:BT_3626 hypothetical protein; SPTR: uncharacterized protein YP_004160717.1 COGs: COG1131 ABC-type multidrug transport system ATPase component; InterPro IPR003439: IPR003593; KEGG: bth:BT_3627 ABC transporter, ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: uncharacterized protein; PFAM: ABC transporter YP_004160718.1 KEGG: bth:BT_3628 hypothetical protein; SPTR: uncharacterized protein YP_004160719.1 KEGG: bth:BT_3629 hypothetical protein; SPTR: uncharacterized protein YP_004160720.1 KEGG: bth:BT_3631 hypothetical protein; SPTR: uncharacterized protein YP_004160721.1 KEGG: bth:BT_3632 hypothetical protein; SPTR: uncharacterized protein YP_004160722.1 InterPro IPR012910: IPR000531; KEGG: bth:BT_3633 hypothetical protein; PFAM: TonB-dependent receptor; TonB-dependent receptor plug; SPTR: uncharacterized protein; PFAM: TonB-dependent Receptor Plug Domain; TonB dependent receptor YP_004160723.1 COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterProIPR002078: IPR001789: IPR002197: IPR003593: IPR 020441; KEGG: bth:BT_3801 RteB, two-component system response regulator; PFAM: sigma-54 factor interaction domain-containing protein; response regulator receiver; helix-turn-helix Fis-type; SMART: response regulator receiver; AAA ATPase; SPTR: uncharacterized protein; PFAM: Response regulator receiver domain; Bacterial regulatory protein, Fis family; Sigma-54 interaction domain YP_004160724.1 COGs: COG0652 peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family; InterPro IPR002130: IPR020892; KEGG: bfs:BF3928 peptidyl-prolyl cis-trans isomerase; PFAM: peptidyl-prolyl cis-trans isomerase cyclophilin type; SPTR: peptidyl-prolyl cis-trans isomerase; PFAM: Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD YP_004160725.1 COGs: COG0612 Zn-dependent peptidase; InterPro IPR011765: IPR007863; KEGG: bfs:BF3927 protease; PFAM: peptidase M16; SPTR: uncharacterized protein; PFAM: peptidase M16 inactive domain; Insulinase (peptidase M16) YP_004160726.1 COGs: COG0534 Na+-driven multidrug efflux pump; InterPro IPR002528; KEGG: bfs:BF3926 transmembrane transport efflux protein; PFAM: multi antimicrobial extrusion protein MatE; SPTR: uncharacterized protein; TIGRFAM: MATE efflux family protein; PFAM: MatE; TIGRFAM: efflux protein, MATE family YP_004160727.1 COGs: COG0642 Signal transduction histidine kinase; InterProIPR005467: IPR001789: IPR008207: IPR003661: IPR 003594: IPR004358; KEGG: bth:BT_3805 two-component system sensor histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; SPTR: uncharacterized protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain YP_004160728.1 InterPro IPR007452; KEGG: bfr:BF4109 hypothetical protein; PFAM: protein of unknown function DUF490; SPTR: uncharacterized protein; PFAM: Family of unknown function (DUF490) YP_004160729.1 COGs: COG4775 Outer membrane protein/protective antigen OMA87; InterPro IPR000184; KEGG: bth:BT_3807 hypothetical protein; PFAM: surface antigen (D15); SPTR: uncharacterized protein; PFAM: Surface antigen YP_004160730.1 KEGG: bth:BT_3808 hypothetical protein; SPTR: uncharacterized protein YP_004160731.1 COGs: COG1132 ABC-type multidrug transport system ATPase and permease components; InterPro IPR003439: IPR017940: IPR001140: IPR003593; KEGG: bth:BT_0073 ABC transporter, ATP-binding protein; PFAM: ABC transporter related; ABC transporter transmembrane region; SMART: AAA ATPase; SPTR: uncharacterized protein; PFAM: ABC transporter transmembrane region; ABC transporter YP_004160732.1 KEGG: bth:BT_0058 hypothetical protein; SPTR: uncharacterized protein YP_004160733.1 KEGG: dae:Dtox_0626 hypothetical protein; SPTR: uncharacterized protein; PFAM: Coenzyme PQQ synthesis protein D (PqqD) YP_004160734.1 KEGG: bth:BT_0074 hypothetical protein; SPTR: uncharacterized protein YP_004160735.1 KEGG: bth:BT_0059 hypothetical protein; SPTR: uncharacterized protein YP_004160736.1 COGs: COG1373 ATPase (AAA+ superfamily); InterPro IPR003593; KEGG: bvu:BVU_0570 hypothetical protein; SMART: AAA ATPase; SPTR: uncharacterized protein YP_004160737.1 KEGG: bvu:BVU_4157 cell surface protein; SPTR: uncharacterized protein YP_004160738.1 KEGG: tcr:507615.73 hypothetical protein; SPTR: uncharacterized protein YP_004160739.1 COGs: COG0488 ATPase components of ABC transporter with duplicated ATPase domains; InterPro IPR003439: IPR003593: IPR017871: IPR006118; KEGG: bth:BT_3809 ABC transporter ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: uncharacterized protein; PFAM: ABC transporter YP_004160740.1 COGs: COG3590 metalloendopeptidase; InterPro IPR008753: IPR018497; KEGG: bfr:BF4102 endothelin-converting enzyme; PFAM: peptidase M13; peptidase M13, neprilysin-like; PRIAM: Neprilysin; SPTR: uncharacterized protein; PFAM: peptidase M13 YP_004160741.1 COGs: COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful); InterPro IPR011607: IPR013982: IPR002695; KEGG: bfs:BF3917 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PFAM: AICARFT/IMPCHase bienzyme formylation region; MGS domain protein; PRIAM: phosphoribosylaminoimidazolecarboxamide formyltransferase; SMART: AICARFT/IMPCHase bienzyme formylation region; SPTR: uncharacterized protein; PFAM: AICARFT/IMPCHase bienzyme; MGS-like domain; TIGRFAM: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase YP_004160742.1 COGs: COG1077 Actin-like ATPase involved in cell morphogenesis; InterPro IPR004753; KEGG: bfs:BF3916 rod shape-determining protein MreB; PFAM: cell shape determining protein MreB/Mrl; SPTR: uncharacterized protein; TIGRFAM: cell shape determining protein, MreB/Mrl family; PFAM: MreB/Mbl protein; TIGRFAM: cell shape determining protein, MreB/Mrl family YP_004160743.1 COGs: COG1792 Cell shape-determining protein; InterPro IPR007221: IPR005223; KEGG: bth:BT_3814 rod shape-determining protein MreC; PFAM: Rod shape-determining protein MreC; SPTR: Rod shape-determining protein MreC; TIGRFAM: rod shape-determining protein MreC; PFAM: rod shape-determining protein MreC; TIGRFAM: rod shape-determining protein MreC YP_004160744.1 InterPro IPR007227; KEGG: bfr:BF4098 hypothetical protein; SPTR: uncharacterized protein; TIGRFAM: rod shape-determining protein MreD; TIGRFAM: rod shape-determining protein MreD YP_004160745.1 COGs: COG0768 Cell division protein FtsI/penicillin-binding protein 2; InterPro IPR005311: IPR001460: IPR017790; KEGG: bfs:BF3913 penicillin-binding protein 2; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; PRIAM: peptidoglycan glycosyltransferase; SPTR: uncharacterized protein; TIGRFAM: penicillin-binding protein 2; PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding Protein dimerisation domain; TIGRFAM: penicillin-binding protein 2 YP_004160746.1 COGs: COG0772 Bacterial cell division membrane protein; InterPro IPR001182: IPR018365; KEGG: bfr:BF4096 rod shape-determining protein RodA; PFAM: cell cycle protein; SPTR: uncharacterized protein; PFAM: Cell cycle protein YP_004160747.1 InterPro IPR020018; KEGG: bfs:BF3911 gliding motility protein; SPTR: uncharacterized protein; TIGRFAM: gliding motility-associated lipoprotein GldH; TIGRFAM: gliding motility-associated lipoprotein GldH YP_004160748.1 COGs: COG1774 Uncharacterized homolog of PSP1; InterPro IPR007557; KEGG: bfs:BF3910 hypothetical protein; PFAM: PSP1 domain protein; SPTR: uncharacterized protein; PFAM: PSP1 C-terminal conserved region YP_004160749.1 COGs: COG2812 DNA polymerase III gamma/tau subunits; KEGG: bth:BT_3820 DNA polymerase III, delta subunit; SPTR: uncharacterized protein; TIGRFAM: DNA polymerase III, delta' subunit YP_004160750.1 COGs: COG0685 5 10-methylenetetrahydrofolate reductase; InterPro IPR003171: IPR004620; KEGG: bth:BT_3821 5,10-methylenetetrahydrofolate reductase; PFAM: methylenetetrahydrofolate reductase; PRIAM: methylenetetrahydrofolate reductase (NAD(P)H); SPTR: methylenetetrahydrofolate reductase; TIGRFAM: 5,10-methylenetetrahydrofolate reductase; PFAM: methylenetetrahydrofolate reductase; TIGRFAM: 5,10-methylenetetrahydrofolate reductase, prokaryotic form YP_004160751.1 InterPro IPR011871; KEGG: bfs:BF3314 lipoprotein; SPTR: uncharacterized protein; PFAM: Fibrobacter succinogenes major domain (Fib_succ_major); TIGRFAM: Fibrobacter succinogenes major paralogous domain YP_004160752.1 COGs: COG1897 Homoserine trans-succinylase; InterPro IPR005697; KEGG: bfr:BF0598 homoserine O-succinyltransferase; PFAM: homoserine O-succinyltransferase; PRIAM: Homoserine O-succinyltransferase; SPTR: Homoserine O-succinyltransferase; TIGRFAM: homoserine O-succinyltransferase; manually curated; PFAM: Homoserine O-succinyltransferase; TIGRFAM: homoserine O-succinyltransferase YP_004160753.1 COGs: COG0826 Collagenase and related protease; InterPro IPR001539; KEGG: bth:BT_2412 collagenase; PFAM: peptidase U32; SPTR: uncharacterized protein; manually curated; PFAM: Collagenase; peptidase U32 YP_004160754.1 KEGG: bth:BT_2411 hypothetical protein; SPTR: uncharacterized protein YP_004160755.1 COGs: COG1629 Outer membrane receptor protein mostly Fe transport; InterPro IPR012910: IPR000531; KEGG: bth:BT_2409 TonB-dependent outer membrane protein; PFAM: TonB-dependent receptor; TonB-dependent receptor plug; SPTR: uncharacterized protein; PFAM: TonB-dependent Receptor Plug Domain; TonB dependent receptor YP_004160756.1 COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR000792; KEGG: bvu:BVU_2046 transcriptional regulator; PFAM: regulatory protein LuxR; SMART: regulatory protein LuxR; SPTR: uncharacterized protein; PFAM: Bacterial regulatory proteins, luxR family YP_004160757.1 COGs: COG2509 Uncharacterized FAD-dependent dehydrogenase; InterPro IPR013027; KEGG: bfs:BF0553 hypothetical protein; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: uncharacterized protein; PFAM: HI0933-like protein YP_004160758.1 COGs: COG1066 ATP-dependent serine protease; InterPro IPR003593: IPR004504; KEGG: bfs:BF0555 DNA repair protein RadA; SMART: AAA ATPase; SPTR: DNA repair protein radA; TIGRFAM: DNA repair protein RadA; PFAM: KaiC; Lon protease (S16) C-terminal proteolytic domain; TIGRFAM: DNA repair protein RadA YP_004160759.1 COGs: COG0252 L-asparaginase/ Glu-tRNAGln amidotransferase subunit D; InterPro IPR006034: IPR006033: IPR020827; KEGG: bfr:BF0607 L-asparaginase I; PFAM: Asparaginase/glutaminase; PRIAM: 1-alkyl-2-acetylglycerophosphocholine esterase; SPTR: uncharacterized protein; TIGRFAM: L-asparaginase, type I; manually curated; PFAM: Asparaginase; TIGRFAM: L-asparaginases, type I YP_004160760.1 COGs: COG0527 Aspartokinase; InterProIPR001048: IPR002912: IPR005106: IPR001342: IPR 001341: IPR011147: IPR018042; KEGG: bth:BT_2403 bifunctional aspartokinase I/homeserine dehydrogenase I; PFAM: homoserine dehydrogenase; aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; homoserine dehydrogenase NAD-binding; SPTR: uncharacterized protein; TIGRFAM: aspartate kinase; manually curated; PFAM: Homoserine dehydrogenase; Homoserine dehydrogenase, NAD binding domain; ACT domain; Amino acid kinase; TIGRFAM: aspartate kinase YP_004160761.1 COGs: COG3635 phosphoglycerate mutase AP superfamily; InterPro IPR019304: IPR006124: IPR013371: IPR004456; KEGG: bfs:BF0559 cofactor-independent phosphoglycerate mutase; PFAM: 2,3-bisphosphoglycerate-independent phosphoglycerate mutase; metalloenzyme domain protein; PRIAM: phosphoglycerate mutase; SPTR: uncharacterized protein; TIGRFAM: proposed homoserine kinase; phosphonopyruvate decarboxylase-related protein; PFAM: 2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Metalloenzyme superfamily; TIGRFAM: 2,3-bisphosphoglycerate-independent phosphoglycerate mutase, archaeal form; proposed homoserine kinase YP_004160762.1 COGs: COG0498 Threonine synthase; InterPro IPR001926: IPR004450: IPR000634; KEGG: bth:BT_2401 threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; PRIAM: Threonine synthase; SPTR: Threonine synthase; TIGRFAM: threonine synthase; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: threonine synthase YP_004160763.1 COGs: COG3746 phosphate-selective porin; InterPro IPR010870; KEGG: bvu:BVU_0532 polyphosphate-selective porin O; PFAM: phosphate-selective porin O and P; SPTR: uncharacterized protein; PFAM: phosphate-selective porin O and P YP_004160764.1 InterPro IPR000326: IPR011158: IPR001011: IPR018296; KEGG: bvu:BVU_0533 acid phosphatase; PFAM: phosphoesterase PA-phosphatase related; PRIAM: Acid phosphatase; SMART: phosphoesterase PA-phosphatase related; SPTR: Acid phosphatase; PFAM: PAP2 superfamily YP_004160765.1 InterPro IPR011110; KEGG: bvu:BVU_0534 hypothetical protein; SPTR: uncharacterized protein YP_004160766.1 COGs: COG1564 Thiamine pyrophosphokinase; InterPro IPR007371: IPR006282; KEGG: bfr:BF0613 hypothetical protein; PFAM: Thiamin pyrophosphokinase catalytic domain-containing protein; SPTR: Thiamine pyrophosphokinase; TIGRFAM: thiamine pyrophosphokinase; PFAM: Thiamin pyrophosphokinase, catalytic domain; TIGRFAM: thiamine pyrophosphokinase YP_004160767.1 COGs: COG3201 Nicotinamide mononucleotide transporter; InterPro IPR006419; KEGG: bfs:BF0564 nicotinamide mononucleotide transporter; PFAM: Nicotinamide mononucleotide transporter PnuC; SPTR: uncharacterized protein; TIGRFAM: nicotinamide mononucleotide transporter PnuC; PFAM: Nicotinamide mononucleotide transporter; TIGRFAM: nicotinamide mononucleotide transporter PnuC YP_004160768.1 COGs: COG1629 Outer membrane receptor protein mostly Fe transport; InterPro IPR012910: IPR000531; KEGG: bfs:BF0565 TonB-dependent transmembrane receptor protein; PFAM: TonB-dependent receptor; TonB-dependent receptor plug; SPTR: TonB-dependent receptor; PFAM: TonB-dependent Receptor Plug Domain; TonB dependent receptor YP_004160769.1 COGs: COG3264 Small-conductance mechanosensitive channel; InterPro IPR006685: IPR006686; KEGG: bfs:BF0566 transmembrane protein; PFAM: MscS Mechanosensitive ion channel; SPTR: uncharacterized protein; PFAM: Mechanosensitive ion channel; Conserved TM helix YP_004160770.1 COGs: COG5006 permease DMT superfamily protein; InterPro IPR000620; KEGG: pdi:BDI_3450 integral membrane protein; PFAM: protein of unknown function DUF6 transmembrane; SPTR: uncharacterized protein; PFAM: EamA-like transporter family YP_004160771.1 COGs: COG0628 permease; InterPro IPR002549; KEGG: bfr:BF0658 permease; PFAM: protein of unknown function UPF0118; SPTR: uncharacterized protein; PFAM: Domain of unknown function DUF20 YP_004160772.1 COGs: COG1435 Thymidine kinase; InterPro IPR020634: IPR001267; KEGG: bfs:BF0583 thymidine kinase; PFAM: thymidine kinase; PRIAM: Thymidine kinase; SPTR: Thymidine kinase; PFAM: Thymidine kinase YP_004160773.1 KEGG: bfr:BF0660 hypothetical protein; SPTR: uncharacterized protein YP_004160774.1 COGs: COG0313 methyltransferase; InterPro IPR000878: IPR008189: IPR018063; KEGG: bth:BT_2273 methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; SPTR: uncharacterized protein; PFAM: Tetrapyrrole (Corrin/Porphyrin) methylases; TIGRFAM: probable S-adenosylmethionine-dependent methyltransferase, YraL family YP_004160775.1 KEGG: bfs:BF0586 hypothetical protein; SPTR: uncharacterized protein YP_004160776.1 COGs: COG1011 hydrolase (HAD superfamily); InterPro IPR005834: IPR011951: IPR006439; KEGG: bth:BT_2271 haloacid dehalogenase-like hydrolase; PFAM: Haloacid dehalogenase domain protein hydrolase; SPTR: uncharacterized protein; TIGRFAM: HAD superfamily (subfamily IA) hydrolase, TIGR02254; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E; HAD superfamily (subfamily IA) hydrolase, TIGR02254 YP_004160777.1 COGs: COG2095 Multiple antibiotic transporter; InterPro IPR002771; KEGG: bth:BT_2270 MarC family integral membrane protein; PFAM: multiple antibiotic resistance (MarC)-related protein; SPTR: uncharacterized protein; PFAM: MarC family integral membrane protein; TIGRFAM: membrane protein, MarC family YP_004160778.1 InterPro IPR012944; KEGG: zpr:ZPR_0689 outer membrane protein, probably involved in nutrient binding; PFAM: RagB/SusD domain protein; SPTR: outer membrane protein, probably involved in nutrient binding; PFAM: SusD family YP_004160779.1 InterPro IPR012910: IPR000531; KEGG: zpr:ZPR_0688 RagA protein; PFAM: TonB-dependent receptor plug; TonB-dependent receptor; SPTR: outer membrane protein; PFAM: TonB-dependent Receptor Plug Domain; TonB dependent receptor YP_004160782.1 KEGG: dfe:Dfer_3579 fibronectin type III domain protein; SPTR: uncharacterized protein YP_004160783.1 InterPro IPR012944; KEGG: bvu:BVU_1848 hypothetical protein; PFAM: RagB/SusD domain protein; SPTR: outer membrane protein, probably involved in nutrient binding; PFAM: SusD family YP_004160784.1 InterPro IPR012910: IPR000531; KEGG: bvu:BVU_1847 hypothetical protein; PFAM: TonB-dependent receptor; TonB-dependent receptor plug; SPTR: TonB-dependent receptor plug domain protein; PFAM: TonB-dependent Receptor Plug Domain; TonB dependent receptor YP_004160785.1 COGs: COG4974 Site-specific recombinase XerD; InterPro IPR002104; KEGG: bfs:BF0593 integrase/transposase; PFAM: integrase; SPTR: uncharacterized protein; PFAM: Phage integrase YP_004160786.1 SPTR: uncharacterized protein YP_004160787.1 InterPro IPR012910: IPR000531; KEGG: pru:PRU_1888 TonB dependent receptor; PFAM: TonB-dependent receptor plug; TonB-dependent receptor; SPTR: RagA protein; PFAM: TonB dependent receptor; TonB-dependent Receptor Plug Domain YP_004160788.1 KEGG: pru:PRU_1889 hypothetical protein; SPTR: liporotein; PFAM: SusD family YP_004160789.1 COGs: COG2262 GTPase; InterPro IPR002917: IPR016496: IPR006073; KEGG: bth:BT_2258 GTP-binding protein; PFAM: GTP-binding protein HSR1-related; SPTR: GTP-binding protein HflX; TIGRFAM: GTP-binding proten HflX; PFAM: GTPase of unknown function; TIGRFAM: GTP-binding protein HflX; small GTP-binding protein domain YP_004160790.1 InterPro IPR002173; KEGG: bfs:BF0599 hypothetical protein; SPTR: uncharacterized protein YP_004160791.1 COGs: COG1951 Tartrate dehydratase alpha subunit/Fumarate hydratase class I N-terminal domain; InterPro IPR004646: IPR004647: IPR011167: IPR020557; KEGG: bth:BT_2256 fumarate hydratase class I, anaerobic; PFAM: Fe-S type hydro-lyase tartrate/fumarate beta region; Fe-S type hydro-lyase tartrate/fumarate alpha region; SPTR: uncharacterized protein; TIGRFAM: hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit; hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit; PFAM: Fumarase C-terminus; Fumarate hydratase (Fumerase); TIGRFAM: hydro-lyases, Fe-S type, tartrate/fumarate subfamily, beta region; hydro-lyases, Fe-S type, tartrate/fumarate subfamily, alpha region YP_004160792.1 COGs: COG3274 conserved hypothetical protein; KEGG: bfs:BF0602 transmembrane acyl-transferase; SPTR: uncharacterized protein; PFAM: Acyltransferase YP_004160793.1 COGs: COG1162 GTPase; InterPro IPR010914: IPR004881; KEGG: bfr:BF0688 ribosome-associated GTPase; PFAM: GTPase EngC; SPTR: uncharacterized protein; TIGRFAM: ribosome small subunit-dependent GTPase A; manually curated; PFAM: Protein of unknown function, DUF258; TIGRFAM: ribosome small subunit-dependent GTPase A YP_004160794.1 COGs: COG0233 Ribosome recycling factor; InterPro IPR015998: IPR002661; KEGG: bfs:BF0619 ribosome recycling factor; PFAM: ribosome recycling factor; SPTR: Ribosome recycling factor; TIGRFAM: ribosome recycling factor; PFAM: Ribosome recycling factor; TIGRFAM: ribosome recycling factor YP_004160795.1 COGs: COG0528 Uridylate kinase; InterPro IPR001048: IPR015963: IPR011817; KEGG: bfs:BF0626 uridylate kinase; PFAM: aspartate/glutamate/uridylate kinase; PRIAM: UMP kinase; SPTR: UMP kinase; TIGRFAM: uridylate kinase; PFAM: Amino acid kinase; TIGRFAM: uridylate kinase YP_004160796.1 COGs: COG2217 Cation transport ATPase; InterProIPR006121: IPR008250: IPR005834: IPR006403: IPR 006416: IPR001757: IPR001756: IPR018303: IPR017969; KEGG: bfs:BF3863 copper transport-related membrane protein; PFAM: E1-E2 ATPase-associated domain protein; Heavy metal transport/detoxification protein; Haloacid dehalogenase domain protein hydrolase; SPTR: uncharacterized protein; TIGRFAM: copper-translocating P-type ATPase; heavy metal translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase; Heavy-metal-associated domain; haloacid dehalogenase-like hydrolase; TIGRFAM: copper-(or silver)-translocating P-type ATPase; heavy metal translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC YP_004160797.1 COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR018060: IPR006121: IPR000005: IPR018062; KEGG: cat:CA2559_00255 regulatory protein; PFAM: helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: uncharacterized protein; PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family YP_004160798.1 COGs: COG1309 Transcriptional regulator; InterPro IPR001647; KEGG: bfs:BF2169 TetR family transcriptional regulator; PFAM: regulatory protein TetR; SPTR: uncharacterized protein; PFAM: Bacterial regulatory proteins, tetR family YP_004160799.1 COGs: COG0534 Na+-driven multidrug efflux pump; InterPro IPR002528; KEGG: bth:BT_2241 DNA-damage-inducible protein F; PFAM: multi antimicrobial extrusion protein MatE; SPTR: uncharacterized protein; TIGRFAM: MATE efflux family protein; PFAM: MatE; TIGRFAM: efflux protein, MATE family YP_004160800.1 InterPro IPR019734: IPR013026: IPR001440; KEGG: bfr:BF0701 hypothetical protein; PFAM: hypothetical protein; SPTR: uncharacterized protein YP_004160801.1 KEGG: pru:PRU_2343 hypothetical protein; SPTR: uncharacterized protein YP_004160802.1 InterPro IPR019115; KEGG: pru:PRU_2721 hypothetical protein; PFAM: Protein of unknown function, Porph ging; SPTR: uncharacterized protein; PFAM: Protein of unknown function (Porph_ging); TIGRFAM: Porphyromonas gingivalis paralogous family TIGR01200 YP_004160804.1 KEGG: bfs:BF3006 hypothetical protein; SPTR: exported protein; PFAM: Protein of unknown function (DUF3244) YP_004160805.1 InterPro IPR019734: IPR013026: IPR001440; KEGG: pdi:BDI_2763 TPR repeat-containing protein; PFAM: hypothetical protein; SMART: Tetratricopeptide repeat; SPTR: TPR-repeat-containing protein; PFAM: Tetratricopeptide repeat YP_004160806.1 COGs: COG0340 Biotin-(acetyl-CoA carboxylase) ligase; InterPro IPR004143: IPR004408; KEGG: bfr:BF0704 biotin-(acetyl-CoA carboxylase) synthetase; PFAM: biotin/lipoate A/B protein ligase; SPTR: uncharacterized protein; TIGRFAM: biotin/acetyl-CoA-carboxylase ligase; PFAM: Biotin/lipoate A/B protein ligase; TIGRFAM: birA, biotin-[acetyl-CoA-carboxylase] ligase region YP_004160807.1 COGs: COG2315 conserved hypothetical protein; KEGG: bfs:BF0633 hypothetical protein; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF419) YP_004160808.1 COGs: COG0792 endonuclease distantly related to Holliday junction resolvase; InterPro IPR003509; KEGG: bfs:BF0634 hypothetical protein; PFAM: Uncharacterised protein family UPF0102; SPTR: UPF0102 protein HMPREF0969_01065; PFAM: Uncharacterised protein family UPF0102 YP_004160809.1 COGs: COG0793 Periplasmic protease; InterPro IPR005151; KEGG: bth:BT_2239 carboxyl-terminal protease; PFAM: peptidase S41; SMART: peptidase S41; SPTR: Carboxyl-terminal protease; PFAM: peptidase S41 YP_004160810.1 KEGG: bfs:BF0636 hypothetical protein; SPTR: uncharacterized protein YP_004160811.1 COGs: COG0590 Cytosine/adenosine deaminase; InterPro IPR002125: IPR016192; KEGG: bfs:BF0637 cytosine deaminase; PFAM: CMP/dCMP deaminase zinc-binding; SPTR: uncharacterized protein; PFAM: Cytidine and deoxycytidylate deaminase zinc-binding region YP_004160812.1 KEGG: bfs:BF0638 hypothetical protein; SPTR: uncharacterized protein YP_004160813.1 COGs: COG1183 phosphatidylserine synthase; InterPro IPR000462; KEGG: bth:BT_2232 CDP-diacylglycerol--serine O-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; SPTR: CDP-diacylglycerol-serine O-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol--serine O-phosphatidyltransferase YP_004160814.1 COGs: COG0688 phosphatidylserine decarboxylase; InterPro IPR004428: IPR003817: IPR018130; KEGG: bfs:BF0640 phosphatidylserine decarboxylase; PFAM: phosphatidylserine decarboxylase-related; PRIAM: phosphatidylserine decarboxylase; SPTR: phosphatidylserine decarboxylase proenzyme; TIGRFAM: phosphatidylserine decarboxylase related protein; PFAM: phosphatidylserine decarboxylase; TIGRFAM: phosphatidylserine decarboxylase precursor-related protein YP_004160815.1 COGs: COG0587 DNA polymerase III alpha subunit; InterProIPR004013: IPR011708: IPR004365: IPR003141: IPR 004805; KEGG: bfs:BF0641 DNA polymerase III alpha subunit; PFAM: DNA polymerase III alpha subunit; PHP domain protein; nucleic acid binding OB-fold tRNA/helicase-type; PRIAM: DNA-directed DNA polymerase; SMART: phosphoesterase PHP domain protein; SPTR: uncharacterized protein; TIGRFAM: DNA polymerase III, alpha subunit; PFAM: PHP domain; Bacterial DNA polymerase III alpha subunit; TIGRFAM: DNA-directed DNA polymerase III (polc) YP_004160816.1 COGs: COG3118 Thioredoxin domain-containing protein; InterProIPR017936: IPR013766: IPR005746: IPR006662: IPR 017937; KEGG: bth:BT_2229 thioredoxin (thioredoxin M); PFAM: Thioredoxin domain-containing protein; SPTR: Thioredoxin; TIGRFAM: thioredoxin; PFAM: Thioredoxin; TIGRFAM: thioredoxin YP_004160817.1 KEGG: bth:BT_2228 hypothetical protein; SPTR: uncharacterized protein YP_004160818.1 KEGG: bth:BT_2208 hypothetical protein; SPTR: uncharacterized protein YP_004160819.1 COGs: COG0802 ATPase or kinase; InterPro IPR003442; KEGG: bfs:BF0654 ATP/GTP-binding transmembrane protein; PFAM: Uncharacterised protein family UPF0079, ATPase; SPTR: uncharacterized protein; PFAM: Uncharacterised P-loop hydrolase UPF0079; TIGRFAM: ATPase, YjeE family YP_004160820.1 COGs: COG1108 ABC-type Mn2+/Zn2+ transport systems permease components; InterPro IPR001626; KEGG: bfs:BF0655 ABC transporter membrane protein; PFAM: ABC-3 protein; SPTR: uncharacterized protein; PFAM: ABC 3 transport family YP_004160821.1 InterPro IPR013090; KEGG: bfs:BF0656 hypothetical protein; SPTR: uncharacterized protein YP_004160822.1 COGs: COG0128 5-enolpyruvylshikimate-3-phosphate synthase; InterPro IPR016228: IPR006264: IPR001986; KEGG: bfs:BF0666 3-phosphoshikimate 1-carboxyvinyltransferase; PFAM: EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase); PRIAM: 3-phosphoshikimate 1-carboxyvinyltransferase; SPTR: 3-phosphoshikimate 1-carboxyvinyltransferase; PFAM: EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase); TIGRFAM: 3-phosphoshikimate 1-carboxyvinyltransferase YP_004160823.1 KEGG: bvu:BVU_2501 hypothetical protein; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF2721) YP_004160824.1 KEGG: bvu:BVU_2234 hypothetical protein; SPTR: uncharacterized protein; PFAM: Aminotransferase class IV YP_004160825.1 COGs: COG0147 Anthranilate/para-aminobenzoate synthase component I; InterPro IPR019999: IPR015890; KEGG: bvu:BVU_2233 para-aminobenzoate synthase component I; PFAM: Chorismate binding-like; SPTR: uncharacterized protein; PFAM: chorismate binding enzyme YP_004160826.1 COGs: COG0793 Periplasmic protease; InterPro IPR012393: IPR011659: IPR005151; KEGG: bfs:BF0080 peptidase/protease; PFAM: peptidase S41; hypothetical protein; SPTR: uncharacterized protein; PFAM: WD40-like Beta Propeller Repeat; peptidase S41 YP_004160827.1 COGs: COG0484 DnaJ-class molecular chaperone with C-terminal Zn finger domain; InterPro IPR001623: IPR010916; KEGG: bvu:BVU_0073 DnaJ domain-containing protein; PFAM: heat shock protein DnaJ domain protein; SMART: heat shock protein DnaJ domain protein; SPTR: uncharacterized protein; PFAM: DnaJ domain; Tellurite resistance protein TerB YP_004160828.1 KEGG: bfs:BF0540 hypothetical protein; SPTR: uncharacterized protein YP_004160829.1 InterPro IPR005902; KEGG: bfs:BF3598 hypothetical protein; SPTR: uncharacterized protein; TIGRFAM: DNA-binding protein; PFAM: Bacterial DNA-binding protein; TIGRFAM: DNA-binding protein, histone-like YP_004160830.1 COGs: COG0337 3-dehydroquinate synthetase; InterPro IPR016303: IPR002658; KEGG: bfs:BF0672 3-dehydroquinate synthase; PFAM: 3-dehydroquinate synthase; PRIAM: 3-dehydroquinate synthase; SPTR: uncharacterized protein; PFAM: 3-dehydroquinate synthase; TIGRFAM: 3-dehydroquinate synthase YP_004160831.1 KEGG: bfs:BF0673 transmembrane protein; SPTR: uncharacterized protein YP_004160832.1 KEGG: bfs:BF0674 hypothetical protein; SPTR: uncharacterized protein YP_004160833.1 COGs: COG1502 phosphatidylserine/phosphatidylglycerophosphate/ cardiolipin synthase; InterPro IPR001736; KEGG: bth:BT_3978 cardiolipin synthetase; PFAM: phospholipase D/Transphosphatidylase; SMART: phospholipase D/Transphosphatidylase; SPTR: uncharacterized protein; PFAM: phospholipase D Active site motif YP_004160834.1 COGs: COG0742 N6-adenine-specific methylase; InterPro IPR004398: IPR002052; KEGG: bth:BT_3979 methyltransferase; PFAM: Conserved hypothetical protein CHP00095; SPTR: uncharacterized protein; manually curated; PFAM: Conserved hypothetical protein 95; TIGRFAM: RNA methyltransferase, RsmD family YP_004160835.1 KEGG: bfr:BF0748 hypothetical protein; SPTR: uncharacterized protein YP_004160836.1 KEGG: bfs:BF0678 hypothetical protein; SPTR: uncharacterized protein YP_004160837.1 COGs: COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member; KEGG: bfs:BF0679 ATP-dependent exodeoxyribonuclease; SPTR: uncharacterized protein; PFAM: PIF1 helicase YP_004160838.1 KEGG: gem:GM21_1897 hypothetical protein; SPTR: uncharacterized protein YP_004160839.1 COGs: COG1696 membrane protein involved in D-alanine export; InterPro IPR004299; KEGG: pdi:BDI_1486 alginate O-acetylation protein, alginate O-acetyltransferase; PFAM: membrane bound O-acyl transferase MBOAT family protein; SPTR: uncharacterized protein; manually curated; PFAM: MBOAT family YP_004160840.1 COGs: COG0013 Alanyl-tRNA synthetase; InterProIPR018165: IPR018164: IPR002318: IPR012947: IPR 003156; KEGG: bfr:BF0761 alanyl-tRNA synthetase; PFAM: Alanyl-tRNA synthetase, class IIc-like; threonyl/alanyl tRNA synthetase; phosphoesterase DHHA1; SPTR: uncharacterized protein; TIGRFAM: alanyl-tRNA synthetase; PFAM: DHHA1 domain; Threonyl and Alanyl tRNA synthetase second additional domain; tRNA synthetases class II (A); TIGRFAM: alanine--tRNA ligase YP_004160841.1 COGs: COG0739 Membrane protein related to metalloendopeptidase; InterPro IPR016047; KEGG: bfs:BF0690 transmembrane peptidase; PFAM: peptidase M23; SPTR: uncharacterized protein; PFAM: peptidase M23 YP_004160842.1 InterPro IPR000551; KEGG: bfs:BF0691 transcriptional regulator protein; PFAM: regulatory protein MerR; SMART: regulatory protein MerR; SPTR: uncharacterized protein YP_004160843.1 COGs: COG0317 Guanosine polyphosphate pyrophosphohydrolase/synthetase; InterProIPR004811: IPR006674: IPR007685: IPR004095: IPR 002912: IPR003607; KEGG: bfr:BF0764 GTP pyrophosphokinase; PFAM: RelA/SpoT domain protein; metal-dependent phosphohydrolase HD sub domain; TGS domain-containing protein; amino acid-binding ACT domain protein; PRIAM: GTP diphosphokinase; SMART: metal-dependent phosphohydrolase HD region; SPTR: uncharacterized protein; TIGRFAM: RelA/SpoT family protein; PFAM: HD domain; TGS domain; Region found in RelA / SpoT proteins; TIGRFAM: (p)ppGpp synthetase, RelA/SpoT family YP_004160844.1 InterPro IPR000189: IPR008258: IPR018392: IPR002482; KEGG: bfs:BF0693 lytic murein transglycosylase; PFAM: Lytic transglycosylase catalytic; peptidoglycan-binding lysin domain; SMART: peptidoglycan-binding LysM; SPTR: uncharacterized protein; PFAM: Transglycosylase SLT domain; LysM domain YP_004160845.1 KEGG: bfs:BF0694 hypothetical protein; SPTR: uncharacterized protein YP_004160846.1 COGs: COG1475 transcriptional regulator protein; InterPro IPR004437: IPR003115; KEGG: bfs:BF0695 ParB-like chromosome partitioning protein; PFAM: ParB domain protein nuclease; SMART: ParB domain protein nuclease; SPTR: uncharacterized protein; TIGRFAM: parB-like partition protein; PFAM: ParB-like nuclease domain; Helix-turn-helix; TIGRFAM: ParB-like partition proteins YP_004160847.1 COGs: COG1192 ATPase involved in chromosome partitioning; KEGG: bfs:BF0696 ParA chromosome partitioning protein; SPTR: ParaA family ATPase; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain YP_004160848.1 KEGG: act:ACLA_092110 mitochondrial inner membrane AAA protease Yta12, SPTR: Mitochondrial inner membrane AAA protease Yta12 YP_004160849.1 COGs: COG0496 acid phosphatase; InterPro IPR002828; KEGG: bfs:BF0698 stationary phase survival protein SurE; PFAM: Survival protein SurE; SPTR: 5'-nucleotidase surE; TIGRFAM: stationary-phase survival protein SurE; PFAM: Survival protein SurE; TIGRFAM: 5'/3'-nucleotidase SurE YP_004160850.1 COGs: COG0763 Lipid A disaccharide synthetase; InterPro IPR003835; KEGG: bth:BT_4004 lipid-A-disaccharide synthase; PFAM: glycosyl transferase 19; PRIAM: Lipid-A-disaccharide synthase; SPTR: Lipid-A-disaccharide synthetase; TIGRFAM: lipid-A-disaccharide synthase; PFAM: Lipid-A-disaccharide synthetase; TIGRFAM: lipid-A-disaccharide synthase YP_004160851.1 KEGG: bfs:BF0700 hypothetical protein; SPTR: uncharacterized protein; manually curated YP_004160852.1 COGs: COG0575 CDP-diglyceride synthetase; InterPro IPR000374; KEGG: bfs:BF0701 phosphatidate cytidylyltransferase; PFAM: phosphatidate cytidylyltransferase; SPTR: phosphatidate cytidylyltransferase; PFAM: Cytidylyltransferase YP_004160853.1 COGs: COG0465 ATP-dependent Zn protease; InterProIPR005936: IPR003960: IPR003959: IPR000642: IPR 003593; KEGG: bfs:BF0702 transmembrane AAA-metalloprotease FtsH; PFAM: AAA ATPase central domain protein; peptidase M41; SMART: AAA ATPase; SPTR: uncharacterized protein; TIGRFAM: ATP-dependent metalloprotease FtsH; PFAM: FtsH Extracellular; peptidase M41; ATPase associated with various cellular activities (AAA); TIGRFAM: ATP-dependent metalloprotease FtsH YP_004160854.1 COGs: COG0799 Iojap protein; InterPro IPR004394; KEGG: bth:BT_4008 hypothetical protein; PFAM: Iojap-related protein; SPTR: Iojap protein 155; TIGRFAM: iojap-like protein; PFAM: Domain of unknown function DUF143; TIGRFAM: iojap-like ribosome-associated protein YP_004160855.1 KEGG: kfl:Kfla_5708 UDP-N-acetylglucosamine pyrophosphorylase; SPTR: UDP-N-acetylglucosamine pyrophosphorylase YP_004160856.1 InterPro IPR007139; KEGG: bfs:BF0704 hypothetical protein; PFAM: protein of unknown function DUF349; SPTR: uncharacterized protein; PFAM: Domain of Unknown Function (DUF349) YP_004160857.1 COGs: COG2239 Mg/Co/Ni transporter MgtE (contains CBS domain); InterPro IPR000644: IPR006669: IPR006668: IPR006667; KEGG: bth:BT_4042 Mg2+ transporter MgtE; PFAM: MgtE intracellular region; CBS domain containing protein; MgtE integral membrane region; SPTR: Magnesium transporter; TIGRFAM: magnesium transporter; PFAM: MgtE intracellular N domain; Divalent cation transporter; CBS domain; TIGRFAM: Mg2+ transporter (mgtE) YP_004160858.1 COGs: COG0030 Dimethyladenosine transferase (rRNA methylation); InterPro IPR011530: IPR020596: IPR001737: IPR020598; KEGG: bth:BT_4043 dimethyladenosine transferase; PFAM: ribosomal RNA adenine methylase transferase; SMART: Ribosomal RNA adenine methylase transferase-like; SPTR: Ribosomal RNA small subunit methyltransferase A; TIGRFAM: dimethyladenosine transferase; PFAM: Ribosomal RNA adenine dimethylase; TIGRFAM: dimethyladenosine transferase YP_004160859.1 InterPro IPR005242; KEGG: bfr:BF0779 dolichol-P-glucose synthetase; SPTR: uncharacterized protein; PFAM: Uncharacterised protein family (UPF0104); TIGRFAM: conserved hypothetical protein YP_004160860.1 COGs: COG2195 Di- and tripeptidase; InterPro IPR001160: IPR002933: IPR011650; KEGG: bth:BT_4045 aminoacyl-histidine dipeptidase; PFAM: peptidase dimerisation domain protein; peptidase M20; PRIAM: Xaa-His dipeptidase; SPTR: uncharacterized protein; TIGRFAM: aminoacyl-histidine dipeptidase; PFAM: peptidase M20/M25/M40; peptidase dimerisation domain; TIGRFAM: aminoacyl-histidine dipeptidase YP_004160861.1 KEGG: vpo:Kpol_534p23 hypothetical protein; SPTR: NADH dehydrogenase subunit 11 YP_004160862.1 COGs: COG1917 conserved hypothetical protein contains double-stranded beta-helix domain; InterPro IPR013096; KEGG: pdi:BDI_1568 hypothetical protein; PFAM: cupin; SPTR: Cupin 2 domain-containing protein; PFAM: Cupin domain YP_004160863.1 InterPro IPR010916; KEGG: bth:BT_1395 hypothetical protein; SPTR: Flavodoxin; TIGRFAM: Listeria/Bacterioides repeat YP_004160864.1 COGs: COG2373 Large extracellular alpha-helical protein; InterPro IPR002890; KEGG: bth:BT_4047 hypothetical protein; PFAM: alpha-2-macroglobulin; SPTR: uncharacterized protein; PFAM: MG2 domain; alpha-2-macroglobulin family YP_004160865.1 InterPro IPR020606: IPR011467; KEGG: bfs:BF0717 hypothetical protein; PFAM: protein of unknown function DUF1573; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF1573) YP_004160866.1 COGs: COG1703 periplasmic protein kinase ArgK and related GTPase of G3E family; InterPro IPR005129; KEGG: bth:BT_4049 arginine/ornithine transport system ATPase; PFAM: ArgK protein; SPTR: uncharacterized protein; TIGRFAM: LAO/AO transport system ATPase; PFAM: ArgK protein; TIGRFAM: LAO/AO transport system ATPase YP_004160867.1 COGs: COG0642 Signal transduction histidine kinase; InterPro IPR005467: IPR004358: IPR003661: IPR003594; KEGG: bth:BT_1802 two-component system sensor histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: Signal transduction histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain YP_004160868.1 InterPro IPR017871: IPR003439: IPR003593; KEGG: bfr:BF0791 ABC transporter ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: uncharacterized protein; PFAM: Protein of unknown function, DUF258 YP_004160869.1 KEGG: bfr:BF0792 ABC transporter ATP-binding protein; SPTR: uncharacterized protein YP_004160870.1 COGs: COG0668 Small-conductance mechanosensitive channel; InterPro IPR006685; KEGG: bfr:BF0793 membrane transport protein; PFAM: MscS Mechanosensitive ion channel; SPTR: uncharacterized protein; PFAM: Mechanosensitive ion channel YP_004160871.1 COGs: COG0642 Signal transduction histidine kinase; InterProIPR005467: IPR003660: IPR004358: IPR003661: IPR 003594; KEGG: fjo:Fjoh_4292 integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: Integral membrane sensor signal transduction histidine kinase; PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain YP_004160872.1 COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789: IPR001867; KEGG: fjo:Fjoh_4291 two component transcriptional regulator; PFAM: response regulator receiver; transcriptional regulator domain-containing protein; SMART: response regulator receiver; SPTR: two component transcriptional regulator, winged helix family; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal YP_004160873.1 InterPro IPR012910: IPR000531; KEGG: bth:BT_0206 hypothetical protein; PFAM: TonB-dependent receptor plug; TonB-dependent receptor; SPTR: outer membrane protein; PFAM: TonB-dependent Receptor Plug Domain; TonB dependent receptor YP_004160874.1 InterPro IPR012944; KEGG: cpi:Cpin_0453 RagB/SusD domain protein; PFAM: RagB/SusD domain protein; SPTR: outer membrane protein; PFAM: SusD family YP_004160875.1 COGs: COG0845 Membrane-fusion protein; InterPro IPR006143; KEGG: bth:BT_4693 cation efflux system protein; PFAM: hemolysin D; SPTR: Cation efflux system protein; TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: HlyD family secretion protein; TIGRFAM: RND family efflux transporter, MFP subunit YP_004160876.1 COGs: COG3696 silver efflux pump; InterPro IPR001036: IPR004763; KEGG: bth:BT_4694 cation efflux system protein; PFAM: acriflavin resistance protein; SPTR: Heavy metal efflux pump, CzcA family; TIGRFAM: heavy metal efflux pump, CzcA family; PFAM: AcrB/AcrD/AcrF family; TIGRFAM: heavy metal efflux pump (cobalt-zinc-cadmium) YP_004160877.1 COGs: COG1538 Outer membrane protein; InterPro IPR003423; KEGG: bth:BT_4695 outer membrane efflux protein precursor; PFAM: outer membrane efflux protein; SPTR: Outer membrane efflux protein; PFAM: Outer membrane efflux protein YP_004160878.1 COGs: COG4585 Signal transduction histidine kinase; InterProIPR013026: IPR000169: IPR001440: IPR003594: IPR 019734; KEGG: bfr:BF0900 hypothetical protein; PFAM: ATP-binding region ATPase domain protein; hypothetical protein; SPTR: uncharacterized protein; PFAM: Histidine kinase YP_004160879.1 KEGG: bvu:BVU_1702 hypothetical protein; SPTR: uncharacterized protein YP_004160880.1 COGs: COG1629 Outer membrane receptor protein mostly Fe transport; InterPro IPR000540: IPR012910: IPR000531; KEGG: bvu:BVU_1701 TonB-dependent receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor plug; SPTR: uncharacterized protein; PFAM: TonB dependent receptor; TonB-dependent Receptor Plug Domain; TIGRFAM: TonB-dependent receptor YP_004160882.1 COGs: COG0642 Signal transduction histidine kinase; InterProIPR005467: IPR000700: IPR004358: IPR000014: IPR 003018: IPR013655: IPR003661: IPR003594; KEGG: bth:BT_1833 two-component system sensor histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; PAS fold-3 domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; SPTR: uncharacterized protein; TIGRFAM: PAS sensor protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; GAF domain; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box YP_004160884.1 InterPro IPR007815; KEGG: bfr:BF0006 hypothetical protein; PFAM: Erythromycin esterase; SPTR: uncharacterized protein; PFAM: Erythromycin esterase YP_004160885.1 COGs: COG1007 NADH:ubiquinone oxidoreductase subunit 2 (chain N); InterPro IPR010096: IPR001750; KEGG: bth:BT_4058 NADH dehydrogenase I, chain N; PFAM: NADH/Ubiquinone/plastoquinone (complex I); SPTR: uncharacterized protein; TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain N; PFAM: NADH-Ubiquinone/plastoquinone (complex I), various chains; TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain N YP_004160886.1 COGs: COG1008 NADH:ubiquinone oxidoreductase subunit 4 (chain M); InterPro IPR003918: IPR010227: IPR018116: IPR001750; KEGG: bth:BT_4059 NADH dehydrogenase I, chain M; PFAM: NADH/Ubiquinone/plastoquinone (complex I); SPTR: uncharacterized protein; TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain M; PFAM: NADH-Ubiquinone/plastoquinone (complex I), various chains; TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain M YP_004160887.1 COGs: COG1009 NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter MnhA subunit; InterProIPR003916: IPR018393: IPR003945: IPR001516: IPR 001750; KEGG: bfs:BF0785 NADH dehydrogenase chain L; PFAM: NADH/Ubiquinone/plastoquinone (complex I); NADH-Ubiquinone oxidoreductase (complex I) chain 5/L domain protein; SPTR: uncharacterized protein; TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain L; PFAM: NADH-Ubiquinone/plastoquinone (complex I), various chains; NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus; TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain L YP_004160888.1 COGs: COG0713 NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K); InterPro IPR001133; KEGG: bth:BT_4061 NADH dehydrogenase I, chain K; PFAM: NADH-ubiquinone oxidoreductase chain 4L; SPTR: uncharacterized protein; PFAM: NADH-ubiquinone/plastoquinone oxidoreductase chain 4L YP_004160889.1 COGs: COG0839 NADH:ubiquinone oxidoreductase subunit 6 (chain J); InterPro IPR001457; KEGG: bfs:BF0787 NADH dehydrogenase chain J; PFAM: NADH-ubiquinone/plastoquinone oxidoreductase chain 6; SPTR: uncharacterized protein; PFAM: NADH-ubiquinone/plastoquinone oxidoreductase chain 6 YP_004160890.1 COGs: COG1143 formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I); InterPro IPR010226: IPR017896: IPR017900; KEGG: bth:BT_4063 NADH dehydrogenase I, chain I; SPTR: uncharacterized protein; PFAM: 4Fe-4S binding domain YP_004160891.1 COGs: COG1005 NADH:ubiquinone oxidoreductase subunit 1 (chain H); InterPro IPR018086: IPR001694; KEGG: bfs:BF0789 NADH dehydrogenase subunit H; PFAM: respiratory-chain NADH dehydrogenase subunit 1; SPTR: uncharacterized protein; PFAM: NADH dehydrogenase YP_004160892.1 COGs: COG0649 NADH:ubiquinone oxidoreductase 49 kD subunit 7; InterPro IPR001268: IPR020396: IPR001135; KEGG: bfs:BF0790 NADH-quinone oxidoreductase chain C/D; PFAM: NADH-ubiquinone oxidoreductase chain 49kDa; NADH dehydrogenase (ubiquinone) 30 kDa subunit; SPTR: uncharacterized protein; PFAM: Respiratory-chain NADH dehydrogenase, 30 Kd subunit; Respiratory-chain NADH dehydrogenase, 49 Kd subunit YP_004160893.1 COGs: COG0838 NADH:ubiquinone oxidoreductase subunit 3 (chain A); InterPro IPR000440; KEGG: bfs:BF0792 NADH-quinone oxidoreductase chain A; PFAM: NADH-ubiquinone/plastoquinone oxidoreductase chain 3; SPTR: NADH-quinone oxidoreductase subunit; PFAM: NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 YP_004160894.1 KEGG: bfs:BF0793 hypothetical protein; SPTR: uncharacterized protein YP_004160895.1 COGs: COG0168 Trk-type K+ transport systems membrane components; InterPro IPR003445; KEGG: bfs:BF0794 potassium uptake protein; PFAM: cation transporter; SPTR: uncharacterized protein; PFAM: Cation transport protein; TIGRFAM: potassium uptake protein, TrkH family YP_004160896.1 COGs: COG0569 K+ transport systems NAD-binding component; InterPro IPR003148: IPR006037: IPR006036; KEGG: bfs:BF0795 potassium transporter peripheral membrane component; PFAM: TrkA-N domain protein; TrkA-C domain protein; SPTR: uncharacterized protein; PFAM: TrkA-N domain; TrkA-C domain YP_004160897.1 COGs: COG1154 Deoxyxylulose-5-phosphate synthase; InterPro IPR005477: IPR020826: IPR005475: IPR005476; KEGG: bfs:BF0796 1-deoxy-D-xylulose-5-phosphate synthase; PFAM: Transketolase central region; Transketolase domain-containing protein; SPTR: uncharacterized protein; TIGRFAM: deoxyxylulose-5-phosphate synthase; PFAM: Transketolase, C-terminal domain; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; Transketolase, pyrimidine binding domain; TIGRFAM: 1-deoxy-D-xylulose-5-phosphate synthase YP_004160898.1 COGs: COG1853 Conserved protein/domain typically associated with flavoprotein oxygenase DIM6/NTAB family; InterPro IPR002563; KEGG: bfs:BF0846 hypothetical protein; PFAM: flavin reductase domain protein FMN-binding; SPTR: uncharacterized protein; PFAM: Flavin reductase like domain YP_004160899.1 COGs: COG4977 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain; InterPro IPR018060: IPR020449: IPR018062: IPR000005; KEGG: cpi:Cpin_4585 AraC family transcriptional regulator; PFAM: helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: AraC family transcriptional regulator; PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family YP_004160900.1 COGs: COG1979 Uncharacterized oxidoreductase Fe-dependent alcohol dehydrogenase; InterPro IPR001670; KEGG: cby:CLM_1584 NADH-dependent butanol dehydrogenase; PFAM: iron-containing alcohol dehydrogenase; SPTR: uncharacterized protein; PFAM: Iron-containing alcohol dehydrogenase YP_004160901.1 COGs: COG0655 Multimeric flavodoxin WrbA; InterPro IPR005025; KEGG: mpd:MCP_1378 iron-sulfur flavoprotein; PFAM: NADPH-dependent FMN reductase; SPTR: Iron-sulfur flavoprotein; PFAM: NADPH-dependent FMN reductase YP_004160902.1 COGs: COG1408 phosphohydrolase; InterPro IPR004843; KEGG: bfr:BF3143 integral membrane protein; PFAM: metallophosphoesterase; SPTR: integral membrane protein; PFAM: Calcineurin-like phosphoesterase YP_004160903.1 InterPro IPR003812; KEGG: gsu:GSU2183 fic family protein; PFAM: filamentation induced by cAMP protein Fic; SPTR: Fic family protein; PFAM: Fic/DOC family YP_004160905.1 KEGG: bfr:BF3845 hypothetical protein; SPTR: uncharacterized protein YP_004160906.1 KEGG: ana:all4106 hypothetical protein YP_004160907.1 KEGG: act:ACLA_001370 glycosyl hydrolase, family 18, SPTR: glycosyl hydrolase, family 18 YP_004160908.1 KEGG: oaa:100089658 hypothetical protein LOC100089658; SPTR: Sensor histidine kinase YP_004160909.1 KEGG: bth:BT_1114 hypothetical protein; SPTR: uncharacterized protein YP_004160910.1 COGs: COG0667 oxidoreductase (related to aryl-alcohol dehydrogenase); InterPro IPR017909: IPR006311: IPR001395; KEGG: bth:BT_1115 aldo/keto reductase; PFAM: aldo/keto reductase; SPTR: Aldo/keto reductase; PFAM: Aldo/keto reductase YP_004160911.1 COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR018060: IPR020449: IPR000005; KEGG: pdi:BDI_1020 transcriptional regulator; PFAM: helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: Transcriptional regulator; manually curated; PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family YP_004160912.1 COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR018060: IPR020449: IPR000005; KEGG: bth:BT_0729 transcriptional regulator; PFAM: helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: AraC family transcriptional regulator; PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family YP_004160913.1 InterPro IPR014982; KEGG: bth:BT_4100 hypothetical protein; PFAM: GSCFA domain protein; SPTR: uncharacterized protein; PFAM: GSCFA family YP_004160914.1 COGs: COG0787 Alanine racemase; InterProIPR000821: IPR013221: IPR004101: IPR001608: IPR 011079; KEGG: bfs:BF0816 bifunctional UDP-N-acetylmuramoyl-tripeptide:D-alanyl-D-alanine ligase/alanine racemase; PFAM: alanine racemase; Mur ligase middle domain protein; cytoplasmic peptidoglycan synthetase domain protein; SPTR: uncharacterized protein; TIGRFAM: alanine racemase; PFAM: Alanine racemase, C-terminal domain; Alanine racemase, N-terminal domain; Mur ligase middle domain; TIGRFAM: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; alanine racemase YP_004160915.1 InterPro IPR006312: IPR003369; KEGG: bth:BT_4102 sec-independent protein translocase; PFAM: sec-independent translocation protein mttA/Hcf106; SPTR: uncharacterized protein; TIGRFAM: twin-arginine translocation protein, TatA/E family subunit; PFAM: mttA/Hcf106 family; TIGRFAM: twin arginine-targeting protein translocase, TatA/E family YP_004160916.1 COGs: COG0805 Sec-independent protein secretion pathway component TatC; InterPro IPR002033: IPR019822; KEGG: bfs:BF0814 sec-independent protein translocase component; PFAM: Sec-independent periplasmic protein translocase; SPTR: Twin arginine-targeting protein translocase TatC; TIGRFAM: Sec-independent protein translocase, TatC subunit; PFAM: Sec-independent protein translocase (TatC); TIGRFAM: Twin arginine targeting (Tat) protein translocase TatC YP_004160917.1 KEGG: tet:TTHERM_00558040 SnoRNA binding domain containing protein YP_004160918.1 COGs: COG1112 Superfamily I DNA and RNA helicase and helicase subunits; KEGG: bth:BT_4104 DNA helicase; SPTR: uncharacterized protein YP_004160919.1 COGs: COG2223 Nitrate/nitrite transporter; InterPro IPR011701; KEGG: bvu:BVU_1794 hexuronate transporter; PFAM: major facilitator superfamily MFS_1; SPTR: Hexuronate transporter; PFAM: Major Facilitator Superfamily YP_004160920.1 COGs: COG3717 5-keto 4-deoxyuronate isomerase; InterPro IPR021120; KEGG: bvu:BVU_1795 5-keto-4-deoxyuronate isomerase; PFAM: KduI/IolB isomerase; PRIAM: 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase; SPTR: 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase; PFAM: KduI/IolB family YP_004160921.1 COGs: COG3775 phosphotransferase system galactitol-specific IIC component; InterPro IPR013014: IPR004703; KEGG: bvu:BVU_1796 phosphotransferase enzyme II, C component; PFAM: PTS system Galactitol-specific IIC component; SPTR: uncharacterized protein; PFAM: PTS system sugar-specific permease component YP_004160923.1 COGs: COG0546 phosphatase; InterProIPR005833: IPR006402: IPR006439: IPR000150: IPR 005834; KEGG: bfr:BF0877 phosphoglycolate phosphatase; PFAM: Haloacid dehalogenase domain protein hydrolase; SPTR: uncharacterized protein; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; manually curated; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E YP_004160924.1 COGs: COG0623 Enoyl-ACP; KEGG: bvu:BVU_1986 enoyl-[acyl-carrier-protein] reductase; PRIAM: Enoyl-[acyl-carrier-protein] reductase (NADH); SPTR: uncharacterized protein YP_004160925.1 COGs: COG0313 methyltransferase; KEGG: bfs:BF0896 hypothetical protein; SPTR: uncharacterized protein; PFAM: Tetrapyrrole (Corrin/Porphyrin) methylases YP_004160926.1 KEGG: bfs:BF0897 transmembrane protein; SPTR: uncharacterized protein YP_004160927.1 COGs: COG0320 Lipoate synthase; InterPro IPR003698: IPR007197: IPR006638; KEGG: bfs:BF0898 lipoyl synthase; PFAM: radical SAM protein; PRIAM: Lipoyl synthase; SMART: Elongator protein 3/MiaB/NifB; SPTR: Lipoyl synthase; TIGRFAM: lipoic acid synthetase; PFAM: Radical SAM superfamily; TIGRFAM: lipoate synthase YP_004160928.1 COGs: COG1506 Dipeptidyl aminopeptidase/acylaminoacyl-peptidase; InterPro IPR002469; KEGG: bfs:BF0899 dipeptidyl peptidase; PFAM: peptidase S9B dipeptidylpeptidase IV domain protein; SPTR: uncharacterized protein; PFAM: Prolyl oligopeptidase; Dipeptidyl peptidase IV (DPP IV) N-terminal region YP_004160929.1 COGs: COG1242 Fe-S oxidoreductase; InterPro IPR005911: IPR007197: IPR006638; KEGG: bfs:BF0903 hypothetical protein; PFAM: radical SAM protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: TIGR01212 family radical SAM protein; TIGRFAM: conserved hypothetical protein; PFAM: Radical SAM superfamily; TIGRFAM: radical SAM protein, TIGR01212 family YP_004160930.1 COGs: COG0426 flavoprotein; InterPro IPR016440: IPR008254; KEGG: bfs:BF0904 flavoprotein; PFAM: flavodoxin/nitric oxide synthase; SPTR: uncharacterized protein; PFAM: Flavodoxin; Metallo-beta-lactamase superfamily YP_004160931.1 COGs: COG0363 6-phosphogluconolactonase/glucosamine-6-phosphate isomerase/deaminase; InterPro IPR018322: IPR018321: IPR006148; KEGG: bfs:BF0905 glucosamine-6-phosphate deaminase; PFAM: glucosamine/galactosamine-6-phosphate isomerase; SPTR: uncharacterized protein; TIGRFAM: glucosamine-6-phosphate isomerase; PFAM: glucosamine-6-phosphate isomerases/6-phosphogluconolactonase; TIGRFAM: glucosamine-6-phosphate isomerase YP_004160932.1 InterPro IPR018631: IPR012547; KEGG: bvu:BVU_1868 hypothetical protein; PFAM: AAA-ATPase-like; protein of unknown function DUF1703; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF1703); Predicted AAA-ATPase YP_004160933.1 KEGG: bfs:BF3003 lipoprotein; SPTR: uncharacterized protein YP_004160934.1 KEGG: bfs:BF4296 hypothetical protein; SPTR: uncharacterized protein YP_004160935.1 KEGG: bfs:BF0205 transmembrane protein; SPTR: uncharacterized protein YP_004160936.1 KEGG: bfs:BF0206 hypothetical protein; SPTR: uncharacterized protein YP_004160937.1 KEGG: bfs:BF0043 hypothetical protein; SPTR: Hypothetical exported protein YP_004160938.1 InterPro IPR018247; KEGG: pdi:BDI_3423 hypothetical protein; SPTR: exported protein YP_004160939.1 InterPro IPR011467; KEGG: bfr:BF3160 hypothetical protein; PFAM: protein of unknown function DUF1573; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF1573) YP_004160940.1 InterPro IPR000223: IPR019759; KEGG: bfs:BF2989 signal peptidase I; PFAM: peptidase S24/S26A/S26B, conserved region; SPTR: Signal peptidase I; TIGRFAM: signal peptidase I; PFAM: peptidase S26; peptidase S24-like; TIGRFAM: signal peptidase I, bacterial type YP_004160941.1 KEGG: bfr:BF4063 hypothetical protein; SPTR: Predicted protein YP_004160942.1 KEGG: phe:Phep_4133 hypothetical protein; SPTR: Predicted protein YP_004160943.1 KEGG: bfr:BF0052 hypothetical protein; SPTR: uncharacterized protein YP_004160944.1 COGs: COG3307 Lipid A core - O-antigen ligase; InterPro IPR007016; KEGG: bfs:BF2988 hypothetical protein; PFAM: O-antigen polymerase; SPTR: uncharacterized protein; PFAM: O-Antigen ligase YP_004160945.1 COGs: COG0845 Membrane-fusion protein; InterPro IPR006143; KEGG: bfr:BF3152 cation efflux system protein; PFAM: hemolysin D; SPTR: uncharacterized protein; TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: HlyD family secretion protein; TIGRFAM: RND family efflux transporter, MFP subunit YP_004160946.1 COGs: COG0841 Cation/multidrug efflux pump; InterPro IPR001036: IPR020053; KEGG: bfs:BF2986 ABC transport system, membrane protein; PFAM: acriflavin resistance protein; SPTR: uncharacterized protein; PFAM: AcrB/AcrD/AcrF family YP_004160947.1 COGs: COG1538 Outer membrane protein; InterPro IPR003423; KEGG: bfr:BF3150 outer membrane protein TolC; PFAM: outer membrane efflux protein; SPTR: uncharacterized protein; PFAM: Outer membrane efflux protein YP_004160948.1 COGs: COG0841 Cation/multidrug efflux pump; InterPro IPR001036; KEGG: bfs:BF2984 ABC transport system, membrane protein; PFAM: acriflavin resistance protein; SPTR: uncharacterized protein; PFAM: AcrB/AcrD/AcrF family YP_004160949.1 COGs: COG0009 translation factor (SUA5); InterPro IPR006070: IPR004388; KEGG: bfs:BF0907 SUA5/YciO/YrdC family protein; PFAM: SUA5/yciO/yrdC domain; SPTR: Sua5/YciO/YrdC/YwlC family protein; TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; PFAM: yrdC domain; TIGRFAM: Sua5/YciO/YrdC/YwlC family protein YP_004160950.1 COGs: COG3525 N-acetyl-beta-hexosaminidase; InterPro IPR001540: IPR015882: IPR015883; KEGG: bvu:BVU_0392 glycoside hydrolase; PFAM: glycoside hydrolase 20; Beta-N-acetylhexosaminidase, subunit a/b; SPTR: glycoside hydrolase 20; PFAM: glycosyl hydrolase 20, catalytic domain; glycosyl hydrolase 20, domain 2 YP_004160951.1 COGs: COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member; InterPro IPR019734: IPR013026: IPR001440: IPR003593; KEGG: bfs:BF0909 helicase; PFAM: hypothetical protein; SMART: AAA ATPase; Tetratricopeptide repeat; SPTR: uncharacterized protein; PFAM: PIF1 helicase YP_004160952.1 COGs: COG0561 hydrolase of the HAD superfamily; InterPro IPR000150: IPR006379: IPR013200; KEGG: bth:BT_4131 hypothetical protein; PFAM: Haloacid dehalogenase domain protein hydrolase type 3; SPTR: uncharacterized protein; TIGRFAM: Cof-like hydrolase; HAD-superfamily hydrolase, subfamily IIB; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily; HAD-superfamily hydrolase, subfamily IIB YP_004160953.1 InterPro IPR001107; KEGG: bth:BT_4194 integral membrane protein; PFAM: band 7 protein; SMART: band 7 protein; SPTR: uncharacterized protein; PFAM: SPFH domain / Band 7 family YP_004160954.1 KEGG: bfs:BF0799 hypothetical protein; SPTR: uncharacterized protein YP_004160955.1 KEGG: bth:BT_4195 hypothetical protein; SPTR: uncharacterized protein YP_004160956.1 KEGG: nve:NEMVE_v1g207844 hypothetical protein; SPTR: uncharacterized protein YP_004160957.1 KEGG: bth:BT_2480 hypothetical protein; SPTR: uncharacterized protein YP_004160958.1 InterPro IPR018976; KEGG: bth:BT_2479 iron-regulated protein A precursor; PFAM: peptidase M75, Imelysin; SPTR: uncharacterized protein; PFAM: Imelysin YP_004160959.1 COGs: COG3488 thiol oxidoreductase; InterPro IPR010538: IPR009056; KEGG: bth:BT_2478 hypothetical protein; PFAM: protein of unknown function DUF1111; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF1111) YP_004160960.1 InterPro IPR010870; KEGG: bth:BT_2477 hypothetical protein; PFAM: phosphate-selective porin O and P; SPTR: uncharacterized protein; PFAM: phosphate-selective porin O and P YP_004160961.1 KEGG: bth:BT_2476 hypothetical protein; SPTR: uncharacterized protein YP_004160962.1 COGs: COG0251 translation initiation inhibitor yjgF family; InterPro IPR006175; KEGG: bth:BT_2475 translation initiation inhibitor; PFAM: Endoribonuclease L-PSP; SPTR: uncharacterized protein; PFAM: Endoribonuclease L-PSP YP_004160963.1 COGs: COG0755 ABC-type transport system involved in cytochrome c biogenesis permease component; InterPro IPR002541; KEGG: bth:BT_2474 cytochrome c biogenesis protein CcsA; PFAM: cytochrome c assembly protein; SPTR: uncharacterized protein; PFAM: ResB-like family; Cytochrome C assembly protein; TIGRFAM: cytochrome c-type biogenesis protein CcsB YP_004160964.1 COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR000792; KEGG: bfs:BF2686 DNA-binding response regulator; PFAM: regulatory protein LuxR; SMART: regulatory protein LuxR; SPTR: uncharacterized protein; PFAM: Bacterial regulatory proteins, luxR family YP_004160965.1 InterPro IPR012312; KEGG: bvu:BVU_2874 hypothetical protein; PFAM: Hemerythrin HHE cation binding domain protein; SPTR: uncharacterized protein YP_004160966.1 COGs: COG3682 transcriptional regulator protein; InterPro IPR005650; KEGG: bfs:BF0820 regulatory protein; PFAM: Penicillinase repressor; SPTR: uncharacterized protein; PFAM: Penicillinase repressor YP_004160967.1 InterPro IPR017936: IPR000866; KEGG: pru:PRU_1669 hypothetical protein; PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; SPTR: uncharacterized protein; PFAM: AhpC/TSA family YP_004160968.1 COGs: COG0810 Periplasmic protein TonB links inner and outer membranes; InterPro IPR006260: IPR008756; KEGG: bvu:BVU_0113 hypothetical protein; PFAM: peptidase M56 BlaR1; TonB domain; SPTR: uncharacterized protein; TIGRFAM: TonB family protein; PFAM: BlaR1 peptidase M56; Gram-negative bacterial tonB protein; TIGRFAM: TonB family C-terminal domain; TC 2.C.1.1.1 YP_004160969.1 InterPro IPR017936: IPR000866; KEGG: pru:PRU_2053 hypothetical protein; PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; SPTR: Thioredoxin family protein; PFAM: AhpC/TSA family YP_004160970.1 COGs: COG1629 Outer membrane receptor protein mostly Fe transport; InterPro IPR012910: IPR000531; KEGG: bfr:BF4254 hypothetical protein; PFAM: TonB-dependent receptor; TonB-dependent receptor plug; SPTR: outer membrane protein probably involved in nutrient binding; PFAM: TonB-dependent Receptor Plug Domain; TonB dependent receptor YP_004160971.1 InterPro IPR012944; KEGG: bvu:BVU_3705 hypothetical protein; PFAM: RagB/SusD domain protein; SPTR: uncharacterized protein; PFAM: SusD family YP_004160972.1 COGs: COG0642 Signal transduction histidine kinase; InterProIPR018060: IPR005467: IPR001789: IPR004358: IPR 011110: IPR003661: IPR003594: IPR000005; KEGG: bth:BT_2826 two-component system sensor histidine kinase/response regulator, hybrid ('one component system'); PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; two component regulator propeller; helix-turn-helix- domain containing protein AraC type; SMART: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; Helix-turn-helix, AraC domain; SPTR: two-component system sensor histidine kinase/response regulator, hybrid (One component system); PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; two component regulator propeller; His Kinase A (phosphoacceptor) domain; Bacterial regulatory helix-turn-helix proteins, AraC family YP_004160973.1 COGs: COG0324 tRNA delta(2)-isopentenylpyrophosphate transferase; InterPro IPR018022: IPR002627; KEGG: bth:BT_4203 tRNA delta(2)-isopentenylpyrophosphate transferase; PFAM: tRNA isopentenyltransferase; PRIAM: tRNA isopentenyltransferase; SPTR: tRNA delta(2)-isopentenylpyrophosphate transferase; TIGRFAM: tRNA delta(2)-isopentenylpyrophosphate transferase; PFAM: IPP transferase; TIGRFAM: tRNA isopentenyltransferase (miaA) YP_004160974.1 KEGG: bfs:BF0826 hypothetical protein; SPTR: uncharacterized protein; PFAM: Plasmid pRiA4b ORF-3-like protein YP_004160975.1 COGs: COG1043 Acyl-(ACP); InterPro IPR010137: IPR001451; KEGG: bth:BT_4205 UDP-N-acetylglucosamine acyltransferase; PFAM: transferase hexapeptide repeat containing protein; PRIAM:Acyl-[acyl-carrier-protein]--UDP-N-acetylgluc osamineO-acyltransferase; SPTR:Acyl-[acyl-carrier-protein]-UDP-N-acetylglucos amineO-acyltransferase; TIGRFAM:acyl-[acyl-carrier-protein]--UDP-N-acetylgl ucosamineO-acyltransferase; TIGRFAM: acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase YP_004160976.1 COGs: COG0774 UDP-3-O-acyl-N-acetylglucosamine deacetylase; InterPro IPR010084: IPR004463: IPR013114; KEGG: bth:BT_4206 bifunctional UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase/(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase; PFAM: UDP-3-0-acyl N-acetylglucosamine deacetylase; Beta-hydroxyacyl-ACP dehydratase FabA/FabZ; SPTR: uncharacterized protein; TIGRFAM: beta-hydroxyacyl-ACP dehydratase FabZ; UDP-3-0-acyl N-acetylglucosamine deacetylase; PFAM: FabA-like domain; UDP-3-O-acyl N-acetylglycosamine deacetylase; TIGRFAM: UDP-3-0-acyl N-acetylglucosamine deacetylase; beta-hydroxyacyl-[ACP] dehydratase FabZ YP_004160977.1 COGs: COG1044 UDP-3-O-(3-hydroxymyristoyl); InterPro IPR007691: IPR020573: IPR001451; KEGG: bfs:BF0829 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; PFAM: UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, non-repeat region; transferase hexapeptide repeat containing protein; SPTR: UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; TIGRFAM: UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; PFAM: UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD; Bacterial transferase hexapeptide (three repeats); TIGRFAM: UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase YP_004160978.1 COGs: COG1078 HD superfamily phosphohydrolase; InterPro IPR006674: IPR003607; KEGG: bth:BT_4208 phosphohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; SPTR: uncharacterized protein; PFAM: HD domain YP_004160979.1 COGs: COG0584 glycerophosphoryl diester phosphodiesterase; InterPro IPR004129; KEGG: pdi:BDI_0402 glycerophosphodiester phosphodiesterase; PFAM: glycerophosphoryl diester phosphodiesterase; SPTR: uncharacterized protein; PFAM: glycerophosphoryl diester phosphodiesterase YP_004160980.1 InterPro IPR000421: IPR015882: IPR011496; KEGG: amu:Amuc_0052 hyalurononglucosaminidase; PFAM: hyaluronidase; Beta-N-acetylhexosaminidase, subunit a/b; coagulation factor 5/8 type domain protein; SPTR: uncharacterized protein; PFAM: F5/8 type C domain; beta-N-acetylglucosaminidase; glycosyl hydrolase 20, domain 2 YP_004160981.1 COGs: COG1835 acyltransferase; InterPro IPR002656; KEGG: bth:BT_2367 acyltransferase; PFAM: acyltransferase; SPTR: uncharacterized protein; PFAM: Acyltransferase YP_004160982.1 COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterPro IPR000595; KEGG: bfs:BF0313 cAMP-binding DNA-binding protein; PFAM: cyclic nucleotide-binding; SPTR: regulatory protein; PFAM: Cyclic nucleotide-binding domain YP_004160983.1 KEGG: bth:BT_0959 hypothetical protein; SPTR: transmembrane protein YP_004160984.1 COGs: COG1453 oxidoreductase of the aldo/keto reductase; InterProIPR017909: IPR017896: IPR006311: IPR017900: IPR 001395; KEGG: bth:BT_0962 aldo/keto reductase; PFAM: aldo/keto reductase; SPTR: uncharacterized protein; PFAM: Aldo/keto reductase; TIGRFAM: Tat (twin-arginine translocation) pathway signal sequence YP_004160985.1 COGs: COG0348 polyferredoxin; InterPro IPR017896: IPR017900; KEGG: bth:BT_0963 ferredoxin-type protein; SPTR: uncharacterized protein; PFAM: 4Fe-4S binding domain YP_004160986.1 COGs: COG1453 oxidoreductase of the aldo/keto reductase; InterPro IPR017896: IPR017900: IPR001395; KEGG: ele:Elen_1288 aldo/keto reductase; PFAM: aldo/keto reductase; SPTR: uncharacterized protein; PFAM: Aldo/keto reductase YP_004160987.1 COGs: COG0642 Signal transduction histidine kinase; InterPro IPR005467: IPR004358: IPR003661: IPR003594; KEGG: bfs:BF2647 two-component system sensor kinase/response regulator fusion protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: uncharacterized protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain YP_004160988.1 COGs: COG0284 Orotidine-5'-phosphate decarboxylase; InterPro IPR011995: IPR001754; KEGG: bfs:BF0831 orotidine 5'-phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase; PRIAM: Orotidine-5'-phosphate decarboxylase; SPTR: uncharacterized protein; TIGRFAM: orotidine 5'-phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase / HUMPS family; TIGRFAM: orotidine 5'-phosphate decarboxylase, subfamily 2 YP_004160989.1 KEGG: fsu:Fisuc_1282 hypothetical protein; SPTR: uncharacterized protein YP_004160990.1 COGs: COG0216 Protein chain release factor A; InterPro IPR004373: IPR000352: IPR005139; KEGG: bvu:BVU_0094 peptide chain release factor 1; PFAM: PCRF domain protein; Class I peptide chain release factor; SPTR: peptide chain release factor 1; PFAM: PCRF domain; RF-1 domain; TIGRFAM: peptide chain release factor 1 YP_004160991.1 KEGG: mpd:MCP_0287 hypothetical protein; SPTR: uncharacterized protein YP_004160992.1 KEGG: mmu:258747 olfactory receptor 1106; SPTR: Olfactory receptor MOR172-6 YP_004160994.1 KEGG: npu:Npun_R3915 hypothetical protein; SPTR: uncharacterized protein YP_004160995.1 COGs: COG0150 phosphoribosylaminoimidazole (AIR) synthetase; InterPro IPR010918; KEGG: bvu:BVU_0092 phosphoribosylformylglycinamidine cyclo-ligase; PFAM: AIR synthase related protein domain protein; PRIAM: phosphoribosylformylglycinamidine cyclo-ligase; SPTR: uncharacterized protein; PFAM: AIR synthase related protein, C-terminal domain YP_004160996.1 COGs: COG3275 regulator of cell autolysis; InterPro IPR010559; KEGG: dfe:Dfer_0857 signal transduction histidine kinase, LytS; PFAM: histidine kinase internal region; SPTR: uncharacterized protein; PFAM: Histidine kinase YP_004160997.1 COGs: COG3279 Response regulator of the LytR/AlgR family; InterPro IPR001789: IPR007492; KEGG: dfe:Dfer_0800 two component transcriptional regulator, LytTR family; PFAM: response regulator receiver; LytTr DNA-binding region; SMART: response regulator receiver; SPTR: two-component response transcriptional regulator; PFAM: Response regulator receiver domain; LytTr DNA-binding domain YP_004160998.1 KEGG: dfe:Dfer_0801 hypothetical protein; SPTR: uncharacterized protein YP_004160999.1 COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR018060: IPR020449: IPR018062: IPR000005; KEGG: bph:Bphy_0499 AraC family transcriptional regulator; PFAM: helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: uncharacterized protein; PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family; AraC-like ligand binding domain YP_004161000.1 InterPro IPR014998; KEGG: str:Sterm_3587 hypothetical protein; PFAM: Domain of unknown function DUF1848; SPTR: uncharacterized protein; PFAM: Domain of unknown function (DUF1848) YP_004161001.1 COGs: COG1704 conserved hypothetical protein; InterPro IPR007156; KEGG: bth:BT_4212 hypothetical protein; PFAM: LemA family protein; SPTR: uncharacterized protein; PFAM: LemA family YP_004161002.1 COGs: COG1512 Beta-propeller domains of methanol dehydrogenase type; InterPro IPR007621; KEGG: bfs:BF0836 hypothetical protein; PFAM: protein of unknown function DUF477; SPTR: uncharacterized protein; PFAM: Domain of unknown function (DUF477) YP_004161003.1 COGs: COG1073 Hydrolase of the alpha/beta superfamily; KEGG: bth:BT_4214 hypothetical protein; SPTR: uncharacterized protein; PFAM: Serine hydrolase (FSH1); lysophospholipase YP_004161004.1 COGs: COG0169 Shikimate 5-dehydrogenase; InterPro IPR013708: IPR006151; KEGG: bth:BT_4215 shikimate 5-dehydrogenase; PFAM: Shikimate dehydrogenase substrate binding domain protein; Shikimate/quinate 5-dehydrogenase; SPTR: uncharacterized protein; PFAM: Shikimate dehydrogenase substrate binding domain; TIGRFAM: shikimate 5-dehydrogenase YP_004161005.1 KEGG: bfs:BF3559 lipoprotein; SPTR: uncharacterized protein YP_004161006.1 COGs: COG2226 methylase involved in ubiquinone/menaquinone biosynthesis; InterPro IPR004033; KEGG: bth:BT_4216 ubiquinone/menaquinone biosynthesis methyltransferase; PFAM: UbiE/COQ5 methyltransferase; SPTR: uncharacterized protein; TIGRFAM: ubiquinone/menaquinone biosynthesis methyltransferase; PFAM: ubiE/COQ5 methyltransferase; TIGRFAM: ubiquinone/menaquinone biosynthesis methyltransferases YP_004161007.1 COGs: COG0152 phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; InterPro IPR001636: IPR018236; KEGG: bvu:BVU_2543 phosphoribosylaminoimidazole-succinocarboxamide synthase; PFAM: SAICAR synthetase; PRIAM: phosphoribosylaminoimidazolesuccinocarboxamide synthase; SPTR: phosphoribosylaminoimidazole-succinocarboxamide synthase; PFAM: SAICAR synthetase; TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase YP_004161008.1 COGs: COG1702 phosphate starvation-inducible protein PhoH predicted ATPase; InterPro IPR003714; KEGG: bfs:BF0841 phosphate starvation-inducible PhoH-like protein; PFAM: PhoH family protein; SPTR: uncharacterized protein; PFAM: PhoH-like protein YP_004161009.1 COGs: COG0739 Membrane protein related to metalloendopeptidase; InterPro IPR016047; KEGG: bth:BT_4391 metalloendopeptidase; PFAM: peptidase M23; SPTR: metalloendopeptidase; PFAM: peptidase M23 YP_004161010.1 COGs: COG3382 conserved hypothetical protein; InterPro IPR005146; KEGG: bfs:BF1035 hypothetical protein; PFAM: B3/4 domain protein; SPTR: uncharacterized protein; PFAM: B3/4 domain YP_004161011.1 InterPro IPR018550; KEGG: bth:BT_3434 hypothetical protein; PFAM: Lipid A 3-O-deacylase-related; SPTR: uncharacterized protein; PFAM: Lipid A 3-O-deacylase (PagL) YP_004161012.1 KEGG: bth:BT_3433 hypothetical protein; SPTR: uncharacterized protein YP_004161013.1 COGs: COG1496 conserved hypothetical protein; InterPro IPR003730; KEGG: bfr:BF1122 hypothetical protein; PFAM: protein of unknown function DUF152; SPTR: uncharacterized protein; PFAM: Multi-copper polyphenol oxidoreductase laccase; TIGRFAM: uncharacterized protein, YfiH family YP_004161014.1 COGs: COG0536 GTPase; InterProIPR014100: IPR006073: IPR005225: IPR006074: IPR 006169: IPR002917; KEGG: bfs:BF1033 GTPase ObgE; PFAM: GTP1/OBG sub domain protein; GTP-binding protein HSR1-related; SPTR: Obg family GTPase CgtA; TIGRFAM: GTP-binding protein Obg/CgtA; small GTP-binding protein; PFAM: GTPase of unknown function; GTP1/OBG; TIGRFAM: Obg family GTPase CgtA; small GTP-binding protein domain YP_004161015.1 COGs: COG0563 Adenylate kinase and related kinase; InterPro IPR000850: IPR006259; KEGG: bth:BT_4387 adenylate kinase; PFAM: adenylate kinase; SPTR: Adenylate kinase; TIGRFAM: adenylate kinase; PFAM: Adenylate kinase; TIGRFAM: adenylate kinases YP_004161016.1 COGs: COG0634 Hypoxanthine-guanine phosphoribosyltransferase; InterPro IPR005904: IPR000836; KEGG: bfs:BF1031 hypoxanthine guanine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; PRIAM: Hypoxanthine phosphoribosyltransferase; SPTR: Hypoxanthine phosphoribosyltransferase; TIGRFAM: hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyl transferase domain; TIGRFAM: hypoxanthine phosphoribosyltransferase YP_004161017.1 COGs: COG3104 Dipeptide/tripeptide permease; InterPro IPR005279: IPR018456: IPR000109; KEGG: bth:BT_4385 di-tripeptide ABC transporter; PFAM: TGF-beta receptor type I/II extracellular region; SPTR: uncharacterized protein; TIGRFAM: amino acid/peptide transporter; PFAM: POT family; TIGRFAM: amino acid/peptide transporter (peptide:H+ symporter), bacterial YP_004161018.1 KEGG: pdi:BDI_3742 transmembrane protein; SPTR: uncharacterized protein YP_004161019.1 COGs: COG0823 Periplasmic component of the Tol biopolymer transport system; InterPro IPR011659; KEGG: pdi:BDI_3581 hypothetical protein; SPTR: uncharacterized protein; PFAM: WD40-like Beta Propeller Repeat YP_004161020.1 KEGG: pru:PRU_1145 hypothetical protein; SPTR: uncharacterized protein YP_004161021.1 COGs: COG0063 sugar kinase; InterPro IPR000631: IPR004443: IPR017953; KEGG: bth:BT_4383 sugar kinase; PFAM: protein of unknown function UPF0031; YjeF-family domain-containing protein; SPTR: uncharacterized protein; TIGRFAM: carbohydrate kinase, YjeF related protein; PFAM: YjeF-related protein N-terminus; Carbohydrate kinase; TIGRFAM: yjeF N-terminal region; yjeF C-terminal region, hydroxyethylthiazole kinase-related YP_004161022.1 KEGG: bfs:BF0842 hypothetical protein; SPTR: uncharacterized protein YP_004161023.1 COGs: COG0101 Pseudouridylate synthase; InterPro IPR001406: IPR020097; KEGG: bth:BT_4237 tRNA pseudouridine synthase A; PFAM: Pseudouridine synthase I, TruA, alpha/beta domain; SPTR: tRNA pseudouridine synthase A; TIGRFAM: tRNA pseudouridine synthase A; PFAM: tRNA pseudouridine synthase; TIGRFAM: pseudouridylate synthase I YP_004161024.1 InterPro IPR000620; KEGG: bfr:BF0926 permease; PFAM: protein of unknown function DUF6 transmembrane; SPTR: uncharacterized protein; PFAM: EamA-like transporter family YP_004161025.1 COGs: COG1755 conserved hypothetical protein; InterPro IPR007269; KEGG: bfs:BF2104 transmembrane protein; PFAM: isoprenylcysteine carboxyl methyltransferase; SPTR: membrane protein; PFAM: isoprenylcysteine carboxyl methyltransferase (ICMT) family YP_004161026.1 KEGG: bfs:BF2105 hypothetical protein; SPTR: uncharacterized protein YP_004161027.1 COGs: COG1956 GAF domain-containing protein; InterPro IPR003018; KEGG: bfr:BF1809 GAF domain-containing protein; PFAM: GAF domain protein; SPTR: uncharacterized protein; PFAM: GAF domain YP_004161028.1 KEGG: bfs:BF0849 hypothetical protein; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF3256) YP_004161029.1 COGs: COG1284 conserved hypothetical protein; InterPro IPR003740: IPR019264; KEGG: bfs:BF0852 transmembrane protein; PFAM: Protein of unknown function DUF2179; protein of unknown function DUF161; SPTR: uncharacterized protein; PFAM: Uncharacterized BCR, YitT family COG1284; Uncharacterized protein conserved in bacteria (DUF2179) YP_004161030.1 COGs: COG0054 Riboflavin synthase beta-chain; InterPro IPR002180; KEGG: bth:BT_4253 6,7-dimethyl-8-ribityllumazine synthase; PFAM: 67-dimethyl-8-ribityllumazine synthase; SPTR: 6,7-dimethyl-8-ribityllumazine synthase; TIGRFAM: 6,7-dimethyl-8-ribityllumazine synthase; PFAM: 6,7-dimethyl-8-ribityllumazine synthase; TIGRFAM: 6,7-dimethyl-8-ribityllumazine synthase YP_004161031.1 InterPro IPR013026; KEGG: bth:BT_4254 hypothetical protein; SPTR: uncharacterized protein YP_004161032.1 COGs: COG1195 Recombinational DNA repair ATPase (RecF pathway); InterPro IPR001238: IPR018078: IPR003395; KEGG: bfr:BF0958 DNA replication and repair protein RecF; PFAM: SMC domain protein; SPTR: DNA replication and repair protein recF; TIGRFAM: DNA replication and repair protein RecF; PFAM: RecF/RecN/SMC N terminal domain; TIGRFAM: recF protein YP_004161033.1 InterPro IPR007922; KEGG: bfs:BF0878 hypothetical protein; PFAM: protein of unknown function DUF721; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF721) YP_004161034.1 COGs: COG1387 Histidinol phosphatase and related hydrolase of the PHP family; InterPro IPR010140: IPR004013; KEGG: bfs:BF0879 histidinol-phosphatase; PFAM: PHP domain protein; SPTR: uncharacterized protein; TIGRFAM: histidinol phosphate phosphatase; PFAM: PHP domain; TIGRFAM: histidinol phosphate phosphatase YP_004161035.1 COGs: COG0212 5-formyltetrahydrofolate cyclo-ligase; InterPro IPR002698; KEGG: bth:BT_4258 5-formyltetrahydrofolate cyclo-ligase; PFAM: 5-formyltetrahydrofolate cyclo-ligase; SPTR: 5-formyltetrahydrofolate cyclo-ligase; TIGRFAM: 5-formyltetrahydrofolate cyclo-ligase; manually curated; PFAM: 5-formyltetrahydrofolate cyclo-ligase; TIGRFAM: 5,10-methenyltetrahydrofolate synthetase YP_004161036.1 COGs: COG0793 Periplasmic protease; InterPro IPR001478: IPR004447: IPR005151; KEGG: bfr:BF0963 carboxy-terminal processing protease precursor; PFAM: peptidase S41; PDZ/DHR/GLGF domain protein; SMART: peptidase S41; PDZ/DHR/GLGF domain protein; SPTR: uncharacterized protein; TIGRFAM: carboxyl-terminal protease; PFAM: peptidase S41; PDZ domain (Also known as DHR or GLGF); TIGRFAM: C-terminal peptidase (prc) YP_004161037.1 COGs: COG2131 Deoxycytidylate deaminase; InterPro IPR016473: IPR016192: IPR002125; KEGG: bfs:BF0882 deoxycytidylate deaminase; PFAM: CMP/dCMP deaminase zinc-binding; SPTR: uncharacterized protein; PFAM: Cytidine and deoxycytidylate deaminase zinc-binding region YP_004161038.1 KEGG: bth:BT_4261 hypothetical protein; SPTR: uncharacterized protein YP_004161039.1 COGs: COG0339 Zn-dependent oligopeptidase; InterPro IPR001567; KEGG: bfs:BF0884 peptidyl-dipeptidase; PFAM: peptidase M3A and M3B thimet/oligopeptidase F; PRIAM: peptidyl-dipeptidase Dcp; SPTR: uncharacterized protein; PFAM: peptidase M3 YP_004161040.1 COGs: COG0057 glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; InterProIPR020831: IPR020832: IPR006424: IPR020830: IPR 020828: IPR020829; KEGG: bth:BT_4263 glyceraldehyde 3-phosphate dehydrogenase; PFAM: glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain; glyceraldehyde 3-phosphate dehydrogenase, catalytic domain; PRIAM: glyceraldehyde-3-phosphate dehydrogenase (phosphorylating); SPTR: glyceraldehyde 3-phosphate dehydrogenase; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I YP_004161041.1 COGs: COG1970 Large-conductance mechanosensitive channel; InterPro IPR001185: IPR019823; KEGG: bfs:BF0886 large-conductance mechanosensitive channel; PFAM: large-conductance mechanosensitive channel; SPTR: uncharacterized protein; TIGRFAM: large conductance mechanosensitive channel protein; PFAM: Large-conductance mechanosensitive channel, MscL; TIGRFAM: large conductance mechanosensitive channel protein YP_004161042.1 COGs: COG0519 GMP synthase PP-ATPase domain/subunit; InterProIPR017926: IPR011702: IPR004739: IPR001674: IPR 000991; KEGG: bfs:BF0887 GMP synthase; PFAM: GMP synthase domain protein; glutamine amidotransferase class-I; SPTR: uncharacterized protein; TIGRFAM: GMP synthase, large subunit; GMP synthase, small subunit; PFAM: Glutamine amidotransferase class-I; GMP synthase C terminal domain; NAD synthase; TIGRFAM: GMP synthase (glutamine-hydrolyzing), C-terminal domain or B subunit; GMP synthase (glutamine-hydrolyzing), N-terminal domain or A subunit YP_004161043.1 COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterPro IPR000595; KEGG: bth:BT_4300 Crp family transcriptional regulator; PFAM: cyclic nucleotide-binding; SPTR: uncharacterized protein; PFAM: Cyclic nucleotide-binding domain YP_004161044.1 COGs: COG3408 glycogen debranching protein; InterPro IPR010401; KEGG: bfs:BF0919 hypothetical protein; PFAM: Amylo-alpha-16-glucosidase; SPTR: uncharacterized protein; PFAM: Amylo-alpha-1,6-glucosidase; glycogen debranching enzyme N terminal; TIGRFAM: glycogen debranching enzyme, archaeal type YP_004161045.1 COGs: COG0438 glycosyltransferase; InterPro IPR001296; KEGG: bvu:BVU_2775 glycosyl transferase; PFAM: glycosyl transferase group 1; SPTR: uncharacterized protein; PFAM: Starch synthase catalytic domain; glycosyl transferases group 1 YP_004161046.1 COGs: COG1449 alpha-amylase/alpha-mannosidase; InterPro IPR004300; KEGG: bfs:BF0921 glycosyl hydrolase; PFAM: glycoside hydrolase 57; PRIAM: alpha-amylase; SPTR: uncharacterized protein; PFAM: glycosyl hydrolase 57 YP_004161047.1 KEGG: bfs:BF0922 hypothetical protein; SPTR: uncharacterized protein YP_004161048.1 COGs: COG0297 glycogen synthase; InterPro IPR013534; KEGG: bvu:BVU_2897 glycosyl transferase; PFAM: Starch synthase catalytic domain-containing protein; PRIAM: Starch synthase; SPTR: uncharacterized protein; PFAM: Starch synthase catalytic domain YP_004161049.1 COGs: COG0414 Panthothenate synthetase; InterPro IPR003721; KEGG: bfs:BF0924 pantoate--beta-alanine ligase; PFAM: Pantoate-beta-alanine ligase; SPTR: Pantothenate synthetase; TIGRFAM: pantoate/beta-alanine ligase; PFAM: Pantoate-beta-alanine ligase; TIGRFAM: pantoate--beta-alanine ligase YP_004161050.1 COGs: COG0853 Aspartate 1-decarboxylase; InterPro IPR003190; KEGG: bfs:BF0925 aspartate alpha-decarboxylase; PFAM: aspartate decarboxylase; PRIAM: Aspartate 1-decarboxylase; SPTR: Aspartate 1-decarboxylase; TIGRFAM: aspartate 1-decarboxylase; PFAM: Aspartate decarboxylase; TIGRFAM: L-aspartate-alpha-decarboxylase YP_004161051.1 InterPro IPR005151; KEGG: pto:PTO0769 hypothetical protein; PFAM: peptidase S41; SPTR: uncharacterized protein; PFAM: peptidase S41 YP_004161052.1 COGs: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase; InterProIPR017927: IPR000759: IPR006004: IPR008333: IPR 001433: IPR019480: IPR013027; KEGG: bth:BT_4310 bifunctional 2-polyprenylphenol hydroxylase/glutamate synthase subunit beta; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain; SPTR: uncharacterized protein; TIGRFAM: glutamate synthase (NADPH), homotetrameric; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Oxidoreductase FAD-binding domain; Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B; Oxidoreductase NAD-binding domain; TIGRFAM: glutamate synthase (NADPH), homotetrameric YP_004161053.1 COGs: COG0642 Signal transduction histidine kinase; InterPro IPR005467: IPR003594; KEGG: dae:Dtox_2301 histidine kinase; PFAM: ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; SPTR: Histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase YP_004161054.1 KEGG: bfr:BF4289 hypothetical protein; SPTR: DNA-binding protein; TIGRFAM: DNA-binding protein, histone-like YP_004161056.1 COGs: COG0172 Seryl-tRNA synthetase; InterProIPR002317: IPR006195: IPR018156: IPR015866: IPR 002314; KEGG: bfs:BF0928 seryl-tRNA synthetase; PFAM: tRNA synthetase class II (G H P and S); Seryl-tRNA synthetase, class IIa-like; PRIAM: Serine--tRNA ligase; SPTR: uncharacterized protein; TIGRFAM: seryl-tRNA synthetase; PFAM: Seryl-tRNA synthetase N-terminal domain; tRNA synthetase class II core domain (G, H, P, S and T); TIGRFAM: seryl-tRNA synthetase YP_004161057.1 COGs: COG0211 Ribosomal protein L27; InterPro IPR001684: IPR018261; KEGG: bfs:BF0929 50S ribosomal protein L27; PFAM: ribosomal protein L27; SPTR: 50S ribosomal protein L27; TIGRFAM: ribosomal protein L27; PFAM: Ribosomal L27 protein; TIGRFAM: ribosomal protein L27 YP_004161058.1 COGs: COG0261 Ribosomal protein L21; InterPro IPR001787; KEGG: bfs:BF0930 50S ribosomal protein L21; PFAM: ribosomal protein L21; SPTR: 50S ribosomal protein L21; TIGRFAM: ribosomal protein L21; manually curated; PFAM: Ribosomal prokaryotic L21 protein; TIGRFAM: ribosomal protein L21 YP_004161059.1 COGs: COG0546 phosphatase; InterPro IPR006439: IPR005834; KEGG: bvu:BVU_3633 HPr(Ser) phosphatase; PFAM: Haloacid dehalogenase domain protein hydrolase; SPTR: uncharacterized protein; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Protein of unknown function (DUF3667); haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E YP_004161060.1 COGs: COG3537 alpha-1 2-mannosidase; InterPro IPR005887: IPR012939; KEGG: bvu:BVU_0628 glycoside hydrolase; PFAM: glycosyl hydrolase 92; SPTR: alpha-1,2-mannosidase; TIGRFAM: alpha-1,2-mannosidase; PFAM: glycosyl hydrolase 92; TIGRFAM: alpha-1,2-mannosidase YP_004161061.1 COGs: COG3537 alpha-1 2-mannosidase; InterPro IPR005887: IPR012939; KEGG: bvu:BVU_0625 glycoside hydrolase; PFAM: glycosyl hydrolase 92; SPTR: glycoside hydrolase 92; TIGRFAM: alpha-1,2-mannosidase; PFAM: glycosyl hydrolase 92; TIGRFAM: alpha-1,2-mannosidase YP_004161062.1 COGs: COG3537 alpha-1 2-mannosidase; InterPro IPR005887: IPR012939; KEGG: bvu:BVU_0624 glycoside hydrolase; PFAM: glycosyl hydrolase 92; SPTR: glycoside hydrolase 92 protein; TIGRFAM: alpha-1,2-mannosidase; PFAM: glycosyl hydrolase 92; TIGRFAM: alpha-1,2-mannosidase YP_004161063.1 KEGG: pdi:BDI_0466 hypothetical protein; SPTR: uncharacterized protein; PFAM: Uncharacterised BCR, COG1649 YP_004161064.1 KEGG: bth:BT_0318 hypothetical protein; SPTR: lipoprotein YP_004161065.1 InterPro IPR012910: IPR000531; KEGG: bth:BT_0317 hypothetical protein; PFAM: TonB-dependent receptor plug; TonB-dependent receptor; SPTR: TonB-dependent receptor plug domain protein; PFAM: TonB-dependent Receptor Plug Domain; TonB dependent receptor YP_004161066.1 COGs: COG4206 Outer membrane cobalamin receptor protein; InterPro IPR012910: IPR000531; KEGG: pru:PRU_1160 TonB dependent receptor; PFAM: TonB-dependent receptor plug; TonB-dependent receptor; SPTR: TonB dependent receptor; PFAM: TonB-dependent Receptor Plug Domain; TonB dependent receptor YP_004161067.1 KEGG: pru:PRU_1161 lipoprotein; SPTR: lipoprotein YP_004161068.1 COGs: COG3669 alpha-L-fucosidase; InterPro IPR016286: IPR000933; KEGG: pru:PRU_1164 alpha-L-fucosidase; PFAM: glycoside hydrolase 29 (alpha-L-fucosidase); SMART: glycoside hydrolase 29 (alpha-L-fucosidase); SPTR: uncharacterized protein; PFAM: alpha-L-fucosidase YP_004161069.1 COGs: COG1262 conserved hypothetical protein; InterPro IPR005532; KEGG: bvu:BVU_1801 glycoside hydrolase; PFAM: protein of unknown function DUF323; SPTR: BNR/Asp-box repeat protein; PFAM: BNR/Asp-box repeat; formylglycine-generating sulfatase enzyme YP_004161070.1 COGs: COG3669 alpha-L-fucosidase; InterPro IPR016286: IPR000933; KEGG: pru:PRU_1164 alpha-L-fucosidase; PFAM: glycoside hydrolase 29 (alpha-L-fucosidase); SMART: glycoside hydrolase 29 (alpha-L-fucosidase); SPTR: uncharacterized protein; PFAM: alpha-L-fucosidase YP_004161071.1 COGs: COG1472 Beta-glucosidase-related glycosidase; InterPro IPR001764: IPR002772; KEGG: bvu:BVU_0556 glycoside hydrolase beta-glycosidase; PFAM: glycoside hydrolase 3; SPTR: glycoside hydrolase 3, candidate beta-glycosidase; PFAM: glycosyl hydrolase 3 C terminal domain; glycosyl hydrolase 3 N terminal domain YP_004161072.1 COGs: COG3537 alpha-1 2-mannosidase; InterPro IPR005887: IPR012939; KEGG: bvu:BVU_0555 glycoside hydrolase; PFAM: glycosyl hydrolase 92; SPTR: glycoside hydrolase 92; TIGRFAM: alpha-1,2-mannosidase; PFAM: glycosyl hydrolase 92; TIGRFAM: alpha-1,2-mannosidase YP_004161073.1 KEGG: bvu:BVU_0565 hypothetical protein; SPTR: uncharacterized protein YP_004161074.1 InterPro IPR011701; KEGG: bth:BT_1034 signal transducer; PFAM: major facilitator superfamily MFS_1; SPTR: AmpG protein; PFAM: Major Facilitator Superfamily YP_004161075.1 COGs: COG2152 glycosylase; InterPro IPR007184; KEGG: bth:BT_1033 hypothetical protein; PFAM: glycosidase related protein; SPTR: uncharacterized protein; PFAM: Domain of unknown function (DUF377) YP_004161076.1 COGs: COG3537 alpha-1 2-mannosidase; InterPro IPR005887: IPR012939; KEGG: bth:BT_1032 hypothetical protein; PFAM: glycosyl hydrolase 92; SPTR: uncharacterized protein; TIGRFAM: alpha-1,2-mannosidase; PFAM: glycosyl hydrolase 92; TIGRFAM: alpha-1,2-mannosidase YP_004161077.1 COGs: COG3735 conserved hypothetical protein; InterPro IPR010891; KEGG: bth:BT_4316 hypothetical protein; PFAM: GumN family protein; SPTR: uncharacterized protein; PFAM: GumN protein YP_004161078.1 COGs: COG0791 Cell wall-associated hydrolase (invasion-associated protein); InterPro IPR000064; KEGG: bfs:BF0932 lipoprotein; PFAM: NLP/P60 protein; SPTR: uncharacterized protein; PFAM: NlpC/P60 family YP_004161079.1 COGs: COG1131 ABC-type multidrug transport system ATPase component; InterPro IPR003439: IPR003593; KEGG: bfs:BF0933 ATP-binding component of ABC transporter protein; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: uncharacterized protein; PFAM: ABC transporter YP_004161080.1 KEGG: bth:BT_4319 hypothetical protein; SPTR: uncharacterized protein YP_004161081.1 COGs: COG0612 Zn-dependent peptidase; InterPro IPR001431: IPR011765: IPR007863; KEGG: bfr:BF1018 zinc protease; PFAM: peptidase M16; SPTR: uncharacterized protein; PFAM: peptidase M16 inactive domain; Insulinase (peptidase M16) YP_004161082.1 COGs: COG2877 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase; InterPro IPR006269: IPR006218; KEGG: bth:BT_4321 2-dehydro-3-deoxyphosphooctonate aldolase; PFAM: DAHP synthetase I/KDSA; SPTR: 3-deoxy-8-phosphooctulonate synthase; TIGRFAM: 2-dehydro-3-deoxyphosphooctonate aldolase; PFAM: DAHP synthetase I family; TIGRFAM: 3-deoxy-8-phosphooctulonate synthase YP_004161083.1 COGs: COG1597 Sphingosine kinase; InterPro IPR001206; KEGG: bfr:BF1020 hypothetical protein; PFAM: diacylglycerol kinase catalytic region; SMART: diacylglycerol kinase catalytic region; SPTR: uncharacterized protein; PFAM: Diacylglycerol kinase catalytic domain; TIGRFAM: lipid kinase, YegS/Rv2252/BmrU family YP_004161084.1 COGs: COG0324 tRNA delta(2)-isopentenylpyrophosphate transferase; InterPro IPR018022: IPR002627; KEGG: bfs:BF0938 tRNA delta(2)-isopentenylpyrophosphate transferase; PFAM: tRNA isopentenyltransferase; PRIAM: tRNA isopentenyltransferase; SPTR: uncharacterized protein; TIGRFAM: tRNA delta(2)-isopentenylpyrophosphate transferase; PFAM: IPP transferase; TIGRFAM: tRNA isopentenyltransferase (miaA) YP_004161085.1 COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR018060: IPR000005; KEGG: bfr:BF3851 transcriptional regulator; PFAM: helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: Transcriptional regulator; PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family YP_004161086.1 KEGG: acd:AOLE_17225 hypothetical protein YP_004161087.1 COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR018060: IPR020449: IPR000005; KEGG: cpi:Cpin_3787 AraC family transcriptional regulator; PFAM: helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: uncharacterized protein; PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family YP_004161088.1 COGs: COG0471 Di- and tricarboxylate transporter; InterPro IPR006037: IPR004680; KEGG: bth:BT_0539 Na+/sulphate transporter; PFAM: Citrate transporter; TrkA-C domain protein; SPTR: uncharacterized protein; PFAM: Citrate transporter; TrkA-C domain YP_004161089.1 COGs: COG0249 Mismatch repair ATPase (MutS family); InterPro IPR000432; KEGG: bfs:BF0496 mismatch repair-like protein; PFAM: DNA mismatch repair protein MutS domain protein; SMART: DNA mismatch repair protein MutS domain protein; SPTR: uncharacterized protein; PFAM: MutS domain V; MutS domain III YP_004161090.1 KEGG: bth:BT_4325 hypothetical protein; SPTR: uncharacterized protein YP_004161091.1 COGs: COG1136 ABC-type antimicrobial peptide transport system ATPase component; InterPro IPR003439: IPR017871; KEGG: bth:BT_4326 ABC transporter ATP-binding protein; PFAM: ABC transporter related; SPTR: uncharacterized protein; PFAM: ABC transporter YP_004161092.1 KEGG: bth:BT_4327 hypothetical protein; SPTR: uncharacterized protein YP_004161093.1 COGs: COG1385 conserved hypothetical protein; InterPro IPR006700; KEGG: bfr:BF1025 16S ribosomal RNA methyltransferase RsmE; PFAM: protein of unknown function DUF558; SPTR: uncharacterized protein; PFAM: RNA methyltransferase; TIGRFAM: RNA methyltransferase, RsmE family YP_004161094.1 COGs: COG1259 conserved hypothetical protein; InterPro IPR001943: IPR003729; KEGG: bfr:BF1026 hypothetical protein; PFAM: protein of unknown function DUF151; UvrB/UvrC protein; SPTR: uncharacterized protein; PFAM: Uncharacterised ACR, COG1259; UvrB/uvrC motif YP_004161095.1 KEGG: bvu:BVU_3613 xanthosine permease; SPTR: uncharacterized protein; PFAM: Nucleoside H+ symporter; TIGRFAM: nucleoside transporter YP_004161096.1 COGs: COG1092 SAM-dependent methyltransferase; InterPro IPR002478; KEGG: bfs:BF0947 hypothetical protein; SMART: PUA domain containing protein; SPTR: uncharacterized protein; PFAM: S-adenosylmethionine-dependent methyltransferase YP_004161097.1 COGs: COG0349 Ribonuclease D; InterPro IPR002562; KEGG: bfs:BF0948 3'-5' exonuclease; PFAM: 3'-5' exonuclease; SMART: 3'-5' exonuclease; SPTR: uncharacterized protein; PFAM: 3'-5' exonuclease YP_004161098.1 KEGG: bfs:BF0949 hypothetical protein; SPTR: uncharacterized protein YP_004161100.1 COGs: COG1674 DNA segregation ATPase FtsK/SpoIIIE and related protein; InterPro IPR002543: IPR018247: IPR018541; KEGG: bfr:BF1033 FtsK/SpoIIIE family cell division protein; PFAM: cell divisionFtsK/SpoIIIE; DNA translocase ftsK gamma; SPTR: uncharacterized protein; PFAM: Ftsk gamma domain; FtsK/SpoIIIE family YP_004161101.1 KEGG: bfs:BF0951 hypothetical protein; SPTR: uncharacterized protein YP_004161102.1 COGs: COG0492 Thioredoxin reductase; InterPro IPR000103: IPR013027: IPR005982: IPR008255; KEGG: bfs:BF0952 thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: Thioredoxin reductase; TIGRFAM: thioredoxin reductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: thioredoxin-disulfide reductase YP_004161103.1 COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterPro IPR000595: IPR012318: IPR001808; KEGG: bfs:BF0954 FNR family transcriptional regulator protein; PFAM: cyclic nucleotide-binding; SMART: cyclic nucleotide-binding; regulatory protein Crp; SPTR: uncharacterized protein; PFAM: Cyclic nucleotide-binding domain YP_004161105.1 COGs: COG3968 Uncharacterized protein related to glutamine synthetase; InterPro IPR008146; KEGG: bfs:BF0955 glutamine synthetase; PFAM: glutamine synthetase catalytic region; SPTR: uncharacterized protein; PFAM: Glutamine synthetase, catalytic domain; Glutamine synthetase type III N terminal YP_004161106.1 KEGG: bfr:BF1041 hypothetical protein; SPTR: uncharacterized protein YP_004161107.1 COGs: COG5146 Pantothenate kinase acetyl-CoA regulated; InterPro IPR002731: IPR011602; KEGG: bvu:BVU_3836 pantothenate kinase; PFAM: Fumble domain protein; ATPase BadF/BadG/BcrA/BcrD type; SPTR: uncharacterized protein; PFAM: Fumble; TIGRFAM: CoA-substrate-specific enzyme activase, ; pantothenate kinase, eukaryotic/staphyloccocal type YP_004161108.1 COGs: COG0539 Ribosomal protein S1; InterPro IPR003029: IPR000110; KEGG: bfs:BF0959 30S ribosomal protein S1; PFAM: RNA binding S1 domain protein; SPTR: uncharacterized protein; PFAM: S1 RNA binding domain; TIGRFAM: ribosomal protein S1 YP_004161109.1 COGs: COG1234 Metal-dependent hydrolase of the beta-lactamase superfamily III; InterPro IPR013471; KEGG: bfr:BF1044 ribonuclease Z; SPTR: Ribonuclease Z; TIGRFAM: ribonuclease Z; PFAM: Metallo-beta-lactamase superfamily; TIGRFAM: ribonuclease Z YP_004161110.1 COGs: COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog; InterPro IPR014284: IPR000838: IPR007627: IPR013249; KEGG: bfs:BF0961 RNA polymerase ECF-type sigma factor; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; SPTR: uncharacterized protein; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family YP_004161111.1 KEGG: bfs:BF0962 hypothetical protein; SPTR: uncharacterized protein YP_004161112.1 KEGG: bfr:BF1047 hypothetical protein; SPTR: uncharacterized protein YP_004161113.1 COGs: COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like (predicted pyrophosphatase) domain; InterPro IPR011551: IPR004518; KEGG: bth:BT_4350 nucleoside triphosphate pyrophosphohydrolase; PFAM: MazG nucleotide pyrophosphohydrolase; SPTR: uncharacterized protein; TIGRFAM: MazG family protein; manually curated; PFAM: MazG nucleotide pyrophosphohydrolase domain; TIGRFAM: MazG family protein YP_004161114.1 InterPro IPR002818; KEGG: pru:PRU_2581 DJ-1/PfpI family/glyoxalase; PFAM: ThiJ/PfpI domain-containing protein; SPTR: uncharacterized protein; PFAM: DJ-1/PfpI family YP_004161115.1 KEGG: bfs:BF0965 transmembrane zinc-binding protein; SPTR: uncharacterized protein YP_004161117.1 COGs: COG0525 Valyl-tRNA synthetase; InterProIPR002303: IPR019754: IPR002300: IPR013155: IPR 019499: IPR001412; KEGG: bth:BT_4353 valyl-tRNA synthetase; PFAM: aminoacyl-tRNA synthetase class Ia; tRNA synthetase valyl/leucyl anticodon-binding; Valyl-tRNA synthetase, class Ia, tRNA binding arm; SPTR: uncharacterized protein; TIGRFAM: valyl-tRNA synthetase; PFAM: tRNA synthetases class I (I, L, M and V); Anticodon-binding domain; Valyl tRNA synthetase tRNA binding arm; TIGRFAM: valyl-tRNA synthetase YP_004161118.1 KEGG: bfr:BF1066 hypothetical protein; SPTR: uncharacterized protein YP_004161119.1 KEGG: bfr:BF1067 hypothetical protein; SPTR: uncharacterized protein YP_004161120.1 COGs: COG0653 Preprotein translocase subunit SecA (ATPase RNA helicase); InterProIPR000185: IPR011115: IPR014018: IPR011130: IPR 001650: IPR011116: IPR004027: IPR020937; KEGG: bth:BT_4362 preprotein translocase subunit SecA; PFAM: SecA DEAD domain protein; SecA preprotein cross-linking region; helicase domain protein; SecA Wing and Scaffold; SEC-C motif domain protein; SPTR: uncharacterized protein; TIGRFAM: preprotein translocase, SecA subunit; PFAM: SecA DEAD-like domain; SecA preprotein cross-linking domain; SEC-C motif; SecA Wing and Scaffold domain; TIGRFAM: preprotein translocase, SecA subunit YP_004161121.1 InterPro IPR002591; KEGG: bfs:BF0984 alkaline phosphatase; PFAM: type I phosphodiesterase/nucleotide pyrophosphatase; SPTR: uncharacterized protein; PFAM: type I phosphodiesterase / nucleotide pyrophosphatase YP_004161122.1 KEGG: bfs:BF0985 transmembrane protein; SPTR: uncharacterized protein YP_004161123.1 COGs: COG1521 transcriptional regulator protein; InterPro IPR004619; KEGG: bfs:BF0989 pantothenate kinase; PFAM: Bvg accessory factor; SPTR: uncharacterized protein; TIGRFAM: transcriptional activator, Baf family; PFAM: Bordetella pertussis Bvg accessory factor family; TIGRFAM: pantothenate kinase, type III YP_004161124.1 KEGG: bfs:BF0990 outer membrane protein; SPTR: uncharacterized protein YP_004161125.1 InterPro IPR019734: IPR013026: IPR001440; KEGG: bth:BT_4368 hypothetical protein; PFAM: hypothetical protein; SMART: Tetratricopeptide repeat; SPTR: uncharacterized protein YP_004161126.1 InterPro IPR010664; KEGG: bth:BT_4369 hypothetical protein; PFAM: protein of unknown function DUF1239; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF1239) YP_004161127.1 COGs: COG1253 Hemolysins and related protein containing CBS domains; InterPro IPR000644: IPR002550: IPR005170; KEGG: bfs:BF0993 CBS domain-containing protein; PFAM: protein of unknown function DUF21; CBS domain containing protein; transporter-associated region; SPTR: uncharacterized protein; manually curated; PFAM: CBS domain; Domain of unknown function DUF21; Transporter associated domain YP_004161128.1 KEGG: bfr:BF1077 peptidyl-prolyl cis-trans isomerase; SPTR: uncharacterized protein YP_004161129.1 COGs: COG0820 Fe-S-cluster redox enzyme; InterPro IPR004383: IPR007197; KEGG: bfs:BF0995 ribosomal RNA large subunit methyltransferase N; PFAM: radical SAM protein; SPTR: Ribosomal RNA large subunit methyltransferase N; TIGRFAM: radical SAM enzyme, Cfr family; PFAM: Radical SAM superfamily; TIGRFAM: radical SAM enzyme, Cfr family YP_004161130.1 KEGG: bfs:BF0996 hypothetical protein; SPTR: uncharacterized protein YP_004161131.1 COGs: COG1995 Pyridoxal phosphate biosynthesis protein; InterPro IPR005255; KEGG: bfs:BF0997 4-hydroxythreonine-4-phosphate dehydrogenase; PFAM: Pyridoxal phosphate biosynthetic protein PdxA; PRIAM: 4-hydroxythreonine-4-phosphate dehydrogenase; SPTR: uncharacterized protein; TIGRFAM: 4-hydroxythreonine-4-phosphate dehydrogenase; PFAM: Pyridoxal phosphate biosynthetic protein PdxA; TIGRFAM: 4-hydroxythreonine-4-phosphate dehydrogenase YP_004161132.1 COGs: COG3604 Transcriptional regulator containing GAF AAA-type ATPase and DNA binding domains; InterPro IPR020441: IPR002078: IPR002197: IPR003593; KEGG: bfs:BF0998 sigma-54 dependent transcriptional regulator; PFAM: sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; SMART: AAA ATPase; SPTR: uncharacterized protein; PFAM: Bacterial regulatory protein, Fis family; Sigma-54 interaction domain YP_004161133.1 KEGG: bth:BT_4376 hypothetical protein; SPTR: uncharacterized protein YP_004161134.1 KEGG: bfr:BF1083 hypothetical protein; SPTR: uncharacterized protein YP_004161135.1 COGs: COG1314 Preprotein translocase subunit SecG; InterPro IPR004692; KEGG: bfs:BF1001 preprotein translocase subunit SecG; PFAM: Preprotein translocase SecG subunit; SPTR: uncharacterized protein; TIGRFAM: preprotein translocase, SecG subunit; PFAM: Preprotein translocase SecG subunit; TIGRFAM: protein translocase, SecG subunit YP_004161136.1 InterPro IPR011701; KEGG: bfs:BF1002 transmembrane transporter; PFAM: major facilitator superfamily MFS_1; SPTR: uncharacterized protein; PFAM: Major Facilitator Superfamily YP_004161137.1 KEGG: bth:BT_4380 hypothetical protein; SPTR: uncharacterized protein; PFAM: Coenzyme PQQ synthesis protein D (PqqD) YP_004161138.1 KEGG: bth:BT_4382 hypothetical protein; SPTR: uncharacterized protein YP_004161139.1 COGs: COG2706 3-carboxymuconate cyclase; KEGG: bfs:BF1038 hypothetical protein; PRIAM: 6-phosphogluconolactonase; SPTR: uncharacterized protein; manually curated; PFAM: 3-carboxy-cis,cis-muconate lactonizing enzyme YP_004161140.1 COGs: COG1472 Beta-glucosidase-related glycosidase; InterPro IPR001764: IPR002772; KEGG: phe:Phep_2280 glycoside hydrolase 3; PFAM: glycoside hydrolase 3; SPTR: uncharacterized protein; tmRNA as predicted by Rfam (RF00023), score 136.16; PFAM: glycosyl hydrolase 3 C terminal domain; glycosyl hydrolase 3 N terminal domain YP_004161141.1 COGs: COG0735 Fe2+/Zn2+ uptake regulation protein; KEGG: bfs:BF1284 hypothetical protein; SPTR: uncharacterized protein; PFAM: Ferric uptake regulator family YP_004161142.1 COGs: COG2217 Cation transport ATPase; InterProIPR006404: IPR006416: IPR001757: IPR008250: IPR 005834: IPR018303; KEGG: bth:BT_2512 cation-transporting ATPase, P-type, zinc-transporting ATPase; PFAM: E1-E2 ATPase-associated domain protein; Haloacid dehalogenase domain protein hydrolase; SPTR: uncharacterized protein; TIGRFAM: heavy metal translocating P-type ATPase; cadmium-translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase; haloacid dehalogenase-like hydrolase; TIGRFAM: heavy metal translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; heavy metal-(Cd/Co/Hg/Pb/Zn)-translocating P-type ATPase YP_004161143.1 InterPro IPR005490; KEGG: bth:BT_1831 hypothetical protein; PFAM: ErfK/YbiS/YcfS/YnhG family protein; SPTR: uncharacterized protein; PFAM: L,D-transpeptidase catalytic domain YP_004161144.1 KEGG: bfs:BF0440 hypothetical protein; SPTR: uncharacterized protein YP_004161145.1 COGs: COG0534 Na+-driven multidrug efflux pump; InterPro IPR002528; KEGG: bvu:BVU_3780 hypothetical protein; PFAM: multi antimicrobial extrusion protein MatE; SPTR: uncharacterized protein; TIGRFAM: MATE efflux family protein; PFAM: MatE; TIGRFAM: efflux protein, MATE family YP_004161146.1 COGs: COG0389 Nucleotidyltransferase/DNA polymerase involved in DNA repair; InterPro IPR017963: IPR001126; KEGG: bfr:BF1131 DNA damage-inducible protein; PFAM: UMUC domain protein DNA-repair protein; PRIAM: DNA-directed DNA polymerase; SPTR: uncharacterized protein; PFAM: impB/mucB/samB family C-terminal; IMS family HHH motif; impB/mucB/samB family YP_004161147.1 COGs: COG3304 membrane protein; InterPro IPR005185; KEGG: bth:BT_4608 hypothetical protein; PFAM: protein of unknown function DUF307; SPTR: uncharacterized protein; PFAM: Domain of unknown function (DUF307) YP_004161148.1 KEGG: bfs:BF1047 hypothetical protein; SPTR: uncharacterized protein; manually curated YP_004161149.1 KEGG: sab:SAB0593 ATP-binding cassette transporter A YP_004161150.1 COGs: COG3279 Response regulator of the LytR/AlgR family; InterPro IPR007492; KEGG: bfr:BF3236 hypothetical protein; PFAM: LytTr DNA-binding region; SPTR: uncharacterized protein; PFAM: LytTr DNA-binding domain YP_004161151.1 COGs: COG4771 Outer membrane receptor for ferrienterochelin and colicins; InterPro IPR012910; KEGG: bfs:BF3075 hypothetical protein; PFAM: TonB-dependent receptor plug; SPTR: uncharacterized protein; PFAM: TonB dependent receptor; TonB-dependent Receptor Plug Domain YP_004161152.1 COGs: COG4704 conserved hypothetical protein; InterPro IPR018673; KEGG: bfs:BF3074 hypothetical protein; PFAM: Protein of unknown function DUF2141; SPTR: uncharacterized protein; PFAM: Uncharacterized protein conserved in bacteria (DUF2141) YP_004161153.1 InterPro IPR002931; KEGG: bvu:BVU_3899 hypothetical protein; PFAM: transglutaminase; SMART: transglutaminase; SPTR: uncharacterized protein; PFAM: Transglutaminase-like superfamily YP_004161154.1 COGs: COG3142 Uncharacterized protein involved in copper resistance; InterPro IPR005627; KEGG: bth:BT_4416 Cu2+ homeostasis protein CutC; PFAM: CutC family protein; SPTR: uncharacterized protein; manually curated; PFAM: CutC family YP_004161155.1 COGs: COG1418 HD superfamily hydrolase; InterProIPR017705: IPR006675: IPR004088: IPR007779: IPR 018111: IPR006674: IPR004087: IPR003607; KEGG: bfs:BF3405 phosphodiesterase; PFAM: metal-dependent phosphohydrolase HD sub domain; K Homology, type 1, subgroup; SMART: metal-dependent phosphohydrolase HD region; KH domain protein; SPTR: uncharacterized protein; TIGRFAM: YmdA/YtgF protein; metal dependent phophohydrolase; PFAM: KH domain; HD domain; Domain of unknown function (DUF3552); TIGRFAM: conserved hypothetical protein YmdA/YtgF; uncharacterized domain HDIG YP_004161156.1 KEGG: bth:BT_4418 hypothetical protein; SPTR: uncharacterized protein; PFAM: Cell division protein ZapA YP_004161157.1 KEGG: bfs:BF3407 hypothetical protein; SPTR: uncharacterized protein YP_004161158.1 KEGG: bth:BT_1571 hypothetical protein; SPTR: uncharacterized protein; PFAM: Uncharacterized protein conserved in bacteria (DUF2141) YP_004161159.1 KEGG: pdi:BDI_1981 hypothetical protein; SPTR: uncharacterized protein YP_004161160.1 KEGG: kcr:Kcr_0473 hypothetical protein; SPTR: uncharacterized protein YP_004161161.1 KEGG: bvu:BVU_0461 hypothetical protein; SPTR: uncharacterized protein YP_004161162.1 COGs: COG0596 hydrolase or acyltransferase (alpha/beta hydrolase superfamily); InterPro IPR000073; KEGG: fjo:Fjoh_0564 alpha/beta hydrolase fold; PFAM: alpha/beta hydrolase fold; SPTR: uncharacterized protein; PFAM: alpha/beta hydrolase fold YP_004161163.1 COGs: COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog; InterPro IPR014284: IPR007627: IPR013249; KEGG: fjo:Fjoh_0563 ECF subfamily RNA polymerase sigma-24 factor; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; SPTR: uncharacterized protein; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; manually curated; PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family YP_004161164.1 KEGG: fjo:Fjoh_0562 hypothetical protein; SPTR: uncharacterized protein YP_004161165.1 COGs: COG0775 Nucleoside phosphorylase; InterPro IPR000845; KEGG: bfs:BF3401 hypothetical protein; PFAM: purine or other phosphorylase 1; SPTR: uncharacterized protein; PFAM: phosphorylase superfamily YP_004161166.1 COGs: COG2832 conserved hypothetical protein; InterPro IPR007401; KEGG: bfr:BF3597 hypothetical protein; PFAM: protein of unknown function DUF454; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF454) YP_004161167.1 COGs: COG2240 Pyridoxal/pyridoxine/pyridoxamine kinase; InterPro IPR013749; KEGG: bfs:BF3861 pyridoxamine kinase; PFAM: phosphomethylpyrimidine kinase type-1; SPTR: Pyridoxamine kinase; PFAM: phosphomethylpyrimidine kinase; TIGRFAM: pyridoxal kinase YP_004161168.1 COGs: COG0720 6-pyruvoyl-tetrahydropterin synthase; InterPro IPR007115; KEGG: pdi:BDI_1299 6-pyruvoyl-tetrahydropterin synthase; PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; SPTR: uncharacterized protein; PFAM: 6-pyruvoyl tetrahydropterin synthase; TIGRFAM: queuosine biosynthesis protein QueD; 6-pyruvoyl tetrahydropterin synthase/QueD family protein YP_004161169.1 COGs: COG0602 Organic radical activating protein; InterPro IPR007197; KEGG: bth:BT_4454 hypothetical protein; PFAM: radical SAM protein; SPTR: uncharacterized protein; PFAM: Radical SAM superfamily YP_004161170.1 COGs: COG3663 G:T/U mismatch-specific DNA glycosylase; KEGG: bfs:BF3386 hypothetical protein; SPTR: uncharacterized protein YP_004161171.1 COGs: COG1509 Lysine 2 3-aminomutase; InterPro IPR018245; KEGG: bfs:BF3383 hypothetical protein; SPTR: uncharacterized protein; TIGRFAM: KamA family protein YP_004161172.1 KEGG: bth:BT_4475 hypothetical protein; SPTR: uncharacterized protein YP_004161173.1 InterPro IPR001611: IPR003591; KEGG: tde:TDE2003 internalin-related protein; PFAM: leucine-rich repeat-containing protein; SPTR: Leucine Rich Repeat domain protein YP_004161174.1 COGs: COG3016 Uncharacterized iron-regulated protein; InterPro IPR007314; KEGG: bfs:BF3448 hypothetical protein; PFAM: protein of unknown function DUF399; SPTR: uncharacterized protein; PFAM: Protein of unknown function, DUF399 YP_004161175.1 COGs: COG0612 Zn-dependent peptidase; InterPro IPR011765: IPR007863; KEGG: bfs:BF3447 peptidase; PFAM: peptidase M16; SPTR: peptidase; PFAM: peptidase M16 inactive domain; Insulinase (peptidase M16) YP_004161176.1 KEGG: bfs:BF3446 lipoprotein; SPTR: uncharacterized protein YP_004161177.1 InterPro IPR012944; KEGG: bfs:BF3445 hypothetical protein; PFAM: RagB/SusD domain protein; SPTR: RagB/SusD domain-containing protein; PFAM: SusD family YP_004161178.1 InterPro IPR012910: IPR000531; KEGG: bfs:BF3444 hypothetical protein; PFAM: TonB-dependent receptor; TonB-dependent receptor plug; SPTR: Membrane protein; PFAM: TonB-dependent Receptor Plug Domain YP_004161179.1 KEGG: bfr:BF3574 hypothetical protein; SPTR: uncharacterized protein; PFAM: Histone H1-like protein Hc1 YP_004161180.1 COGs: COG4277 DNA-binding protein with the Helix-hairpin-helix motif; InterPro IPR007197: IPR000532; KEGG: bfs:BF3376 hypothetical protein; PFAM: radical SAM protein; SPTR: uncharacterized protein YP_004161181.1 KEGG: bth:BT_4483 hypothetical protein; SPTR: uncharacterized protein YP_004161182.1 COGs: COG0741 Soluble lytic murein transglycosylase and related regulatory protein (some contain LysM/invasin domains); InterPro IPR008258: IPR000189; KEGG: bth:BT_4487 membrane-bound lytic murein transglycosylase; PFAM: Lytic transglycosylase catalytic; SPTR: uncharacterized protein; PFAM: Transglycosylase SLT domain YP_004161183.1 COGs: COG0300 Short-chain dehydrogenase of various substrate specificities; InterPro IPR002347: IPR002198; KEGG: bth:BT_4496 oxidoreductase; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: uncharacterized protein; PFAM: short chain dehydrogenase YP_004161184.1 COGs: COG2030 Acyl dehydratase; InterPro IPR002539; KEGG: bth:BT_4503 hypothetical protein; PFAM: MaoC domain protein dehydratase; PRIAM: Enoyl-CoA hydratase; SPTR: uncharacterized protein; PFAM: MaoC like domain YP_004161185.1 COGs: COG3695 methylated DNA-protein cysteine methyltransferase; InterPro IPR014048: IPR001497; KEGG: pdi:BDI_2036 methylated-DNA methyltransferase; PFAM: methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding; SPTR: uncharacterized protein; TIGRFAM: methylated-DNA/protein-cysteine methyltransferase; PFAM: 6-O-methylguanine DNA methyltransferase, DNA binding domain; TIGRFAM: O-6-methylguanine DNA methyltransferase YP_004161186.1 COGs: COG0648 Endonuclease IV; InterPro IPR001719: IPR012307: IPR018246; KEGG: bth:BT_4651 endonuclease IV; PFAM: Xylose isomerase domain-containing protein TIM barrel; PRIAM: Deoxyribonuclease IV (phage-T(4)-induced); SMART: AP endonuclease 2; SPTR: Probable endonuclease 4; TIGRFAM: apurinic endonuclease Apn1; PFAM: Xylose isomerase-like TIM barrel; TIGRFAM: apurinic endonuclease (APN1) YP_004161187.1 InterPro IPR020483; KEGG: bth:BT_4497 hypothetical protein; SPTR: uncharacterized protein; PFAM: Nitrous oxide-stimulated promoter YP_004161188.1 COGs: COG1670 Acetyltransferase including N-acetylase of ribosomal protein; InterPro IPR000182; KEGG: pdi:BDI_2175 acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: uncharacterized protein; PFAM: Acetyltransferase (GNAT) family YP_004161189.1 COGs: COG0564 Pseudouridylate synthase 23S RNA-specific; InterPro IPR006145: IPR006224; KEGG: bfr:BF1141 ribosomal large subunit pseudouridine synthase A; PFAM: pseudouridine synthase; SPTR: Pseudouridine synthase; PFAM: RNA pseudouridylate synthase; TIGRFAM: pseudouridine synthase, RluA family YP_004161190.1 KEGG: bfs:BF1060 dehydrogenase/oxidoreductase; SPTR: uncharacterized protein YP_004161191.1 KEGG: bth:BT_0658 hypothetical protein; SPTR: uncharacterized protein YP_004161192.1 COGs: COG4783 Zn-dependent protease contains TPR repeats; InterPro IPR001915; KEGG: pdi:BDI_0072 Zn-dependent protease with chaperone function; PFAM: peptidase M48 Ste24p; SPTR: uncharacterized protein; PFAM: peptidase M48 YP_004161193.1 COGs: COG0590 Cytosine/adenosine deaminase; InterPro IPR002125: IPR016192; KEGG: fsu:Fisuc_2567 CMP/dCMP deaminase zinc-binding protein; PFAM: CMP/dCMP deaminase zinc-binding; SPTR: CMP/dCMP deaminase zinc-binding protein; PFAM: Cytidine and deoxycytidylate deaminase zinc-binding region YP_004161194.1 COGs: COG0332 3-oxoacyl-ACP; InterPro IPR004655: IPR013751: IPR013747; KEGG: bth:BT_0122 3-oxoacyl-(ACP) synthase III; PFAM: 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III domain-containing protein; 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III; PRIAM: Beta-ketoacyl-acyl-carrier-protein synthase I; SPTR: 3-oxoacyl-ACP synthase III; TIGRFAM: 3-oxoacyl-ACP synthase III; PFAM: 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal; 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III; TIGRFAM: 3-oxoacyl-ACP synthase III YP_004161195.1 COGs: COG0566 rRNA methylase; InterPro IPR001537; KEGG: bfs:BF1278 SpoU-like rRNA methylase; PFAM: tRNA/rRNA methyltransferase (SpoU); SPTR: uncharacterized protein; PFAM: SpoU rRNA methylase YP_004161197.1 KEGG: bth:BT_4675 heparin lyase I precursor; PRIAM: Heparin lyase; SPTR: uncharacterized protein YP_004161198.1 COGs: COG3119 Arylsulfatase A; InterPro IPR000917; KEGG: dfe:Dfer_2520 sulfatase; PFAM: sulfatase; SPTR: uncharacterized protein; PFAM: Sulfatase YP_004161199.1 COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358: IPR018060: IPR005467: IPR001789: IPR 011110: IPR011123: IPR003661: IPR003594: IPR000005; KEGG: bth:BT_4663 two-component system sensor histidine kinase/response; PFAM: ATP-binding region ATPase domain protein; two component regulator three Y domain-containing protein; two component regulator propeller; histidine kinase A domain protein; response regulator receiver; helix-turn-helix- domain containing protein AraC type; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; Helix-turn-helix, AraC domain; SPTR: uncharacterized protein; PFAM: Y_Y_Y domain; Response regulator receiver domain; two component regulator propeller; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; Bacterial regulatory helix-turn-helix proteins, AraC family YP_004161200.1 COGs: COG2017 Galactose mutarotase; InterPro IPR008183: IPR018052; KEGG: dfe:Dfer_2820 aldose 1-epimerase; PFAM: Aldose 1-epimerase; PRIAM: Aldose 1-epimerase; SPTR: uncharacterized protein; manually curated; PFAM: Aldose 1-epimerase YP_004161201.1 COGs: COG1917 conserved hypothetical protein contains double-stranded beta-helix domain; InterPro IPR013096; KEGG: bvu:BVU_1812 pectin degradation protein; PFAM: cupin; SPTR: uncharacterized protein; PFAM: Cupin domain YP_004161202.1 InterPro IPR012910: IPR000531; KEGG: phe:Phep_2829 TonB-dependent receptor plug; PFAM: TonB-dependent receptor; TonB-dependent receptor plug; SPTR: uncharacterized protein; manually curated; PFAM: TonB-dependent Receptor Plug Domain; TonB dependent receptor YP_004161203.1 InterPro IPR012944; KEGG: phe:Phep_2828 RagB/SusD domain protein; PFAM: RagB/SusD domain protein; SPTR: uncharacterized protein; PFAM: SusD family YP_004161204.1 InterPro IPR010905: IPR003016; KEGG: bth:BT_4658 glucuronyl hydrolase; PFAM: glycosyl hydrolase 88; SPTR: uncharacterized protein; PFAM: glycosyl Hydrolase 88 YP_004161205.1 InterPro IPR012480; KEGG: bth:BT_4657 heparinase III protein; PFAM: Heparinase II/III family protein; SPTR: uncharacterized protein; PFAM: Heparinase II/III-like protein YP_004161206.1 COGs: COG3119 Arylsulfatase A; InterPro IPR000917; KEGG: bth:BT_4656 N-acetylglucosamine-6-sulfatase precursor; PFAM: sulfatase; SPTR: uncharacterized protein; PFAM: Sulfatase YP_004161207.1 InterPro IPR006311; KEGG: bth:BT_4655 hypothetical protein; SPTR: uncharacterized protein YP_004161208.1 COGs: COG1940 Transcriptional regulator/sugar kinase; InterPro IPR000600: IPR016160; KEGG: bth:BT_4654 ROK family transcriptional repressor; PFAM: ROK family protein; SPTR: uncharacterized protein; PFAM: ROK family; TIGRFAM: ROK family protein ( glucokinase) YP_004161209.1 COGs: COG0738 Fucose permease; InterPro IPR011701; KEGG: bth:BT_4653 glucose/galactose transporter; PFAM: major facilitator superfamily MFS_1; SPTR: uncharacterized protein; PFAM: Major Facilitator Superfamily YP_004161210.1 KEGG: bth:BT_4652 hypothetical protein; SPTR: uncharacterized protein; PFAM: Heparinase II/III-like protein YP_004161211.1 COGs: COG3119 Arylsulfatase A; InterPro IPR000917; KEGG: art:Arth_1708 sulfatase; PFAM: sulfatase; SPTR: uncharacterized protein; PFAM: Sulfatase YP_004161212.1 KEGG: eca:ECA0413 hypothetical protein; SPTR: uncharacterized protein YP_004161213.1 InterPro IPR002104; KEGG: bvu:BVU_3179 integrase; PFAM: integrase; SPTR: Predicted protein; PFAM: Phage integrase YP_004161214.1 KEGG: dgr:Dgri_GH12492 GH12492 gene product from transcript GH12492-RA YP_004161215.1 KEGG: bfr:BF3455 tyrosine type site-specific recombinase; SPTR: Predicted protein YP_004161216.1 KEGG: bfr:BF3455 tyrosine type site-specific recombinase; SPTR: Predicted protein YP_004161217.1 InterPro IPR001387; KEGG: bfr:BF1147 transcriptional regulator; PFAM: hypothetical protein; SMART: hypothetical protein; SPTR: transcriptional regulator; PFAM: Helix-turn-helix YP_004161218.1 COGs: COG3550 conserved hypothetical protein; InterPro IPR012894: IPR012893; KEGG: bfr:BF1148 hypothetical protein; PFAM: HipA domain protein; SPTR: Toxin-antitoxin system, toxin component, HipA family; PFAM: HipA-like C-terminal domain; HipA-like N-terminal domain YP_004161219.1 KEGG: bfr:BF1149 hypothetical protein; SPTR: uncharacterized protein YP_004161220.1 InterPro IPR001387; KEGG: bfs:BF1116 DNA-binding protein; PFAM: hypothetical protein; SMART: hypothetical protein; SPTR: DNA-binding protein; PFAM: Helix-turn-helix YP_004161221.1 COGs: COG1451 metal-dependent hydrolase; InterPro IPR002725; KEGG: scb:SCAB_29221 hypothetical protein; PFAM: protein of unknown function DUF45; SPTR: Zinc metalloprotease; PFAM: Protein of unknown function DUF45 YP_004161222.1 COGs: COG0610 type I site-specific restriction-modification system R (restriction) subunit and related helicase; InterProIPR004473: IPR014021: IPR007409: IPR006935: IPR 014001; KEGG: bfs:BF1079 type I restriction enzyme; PFAM: protein of unknown function DUF450; type III restriction protein res subunit; SMART: DEAD-like helicase; SPTR: type I site-specific deoxyribonuclease, HsdR family; TIGRFAM: type I site-specific deoxyribonuclease, HsdR family; PFAM: type I restriction enzyme R protein N terminus (HSDR_N); type III restriction enzyme, res subunit; TIGRFAM: type I site-specific deoxyribonuclease, HsdR family YP_004161223.1 COGs: COG0286 type I restriction-modification system methyltransferase subunit; InterPro IPR002296: IPR003356: IPR002052; KEGG: tgr:Tgr7_1779 type I restriction-modification system specificity subunit; PFAM: N-6 DNA methylase; SPTR: type I restriction-modification system, M subunit; PFAM: N-6 DNA methylase; HsdM N-terminal domain; TIGRFAM: type I restriction system adenine methylase (hsdM) YP_004161224.1 COGs: COG0732 Restriction endonuclease S subunits; InterPro IPR000055; KEGG: fma:FMG_0078 type I restriction-modification enzyme specificity subunit; PFAM: restriction modification system DNA specificity domain; SPTR: type I restriction-modification enzyme specificity subunit; PFAM: type I restriction modification DNA specificity domain YP_004161225.1 InterPro IPR005829; KEGG: bth:BT_4745 hypothetical protein; SPTR: uncharacterized protein YP_004161226.1 KEGG: bhy:BHWA1_01798 TPR domain-containing protein; SPTR: TPR domain-containing protein YP_004161227.1 KEGG: cel:R07G3.3 Nuclear Pore complex Protein; SPTR: uncharacterized protein YP_004161228.1 COGs: COG2184 Protein involved in cell division; InterPro IPR003812; KEGG: bth:BT_4222 hypothetical protein; PFAM: filamentation induced by cAMP protein Fic; SPTR: Cell filamentation protein Fic-related protein; PFAM: Fic/DOC family YP_004161229.1 COGs: COG1479 conserved hypothetical protein; InterPro IPR020305: IPR004919; KEGG: bln:Blon_0814 protein of unknown function DUF262; PFAM: protein of unknown function DUF262; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF1524); Protein of unknown function DUF262 YP_004161230.1 InterPro IPR004919; KEGG: bln:Blon_0815 protein of unknown function DUF262; PFAM: protein of unknown function DUF262; SPTR: uncharacterized protein; PFAM: Protein of unknown function DUF262 YP_004161231.1 InterPro IPR004256; KEGG: bfs:BF1799 ATP/GTP-binding protein; PFAM: DUF234 DEXX-box ATPase; SPTR: uncharacterized protein; PFAM: Archaeal ATPase; Archaea bacterial proteins of unknown function YP_004161232.1 KEGG: bfr:BF1161 hypothetical protein; SPTR: uncharacterized protein YP_004161233.1 KEGG: bfs:BF1134 transmembrane protein; SPTR: uncharacterized protein YP_004161234.1 COGs: COG4974 Site-specific recombinase XerD; InterPro IPR002104; KEGG: bfs:BF1136 bacteriophage integrase; PFAM: integrase; SPTR: bacteriophage integrase; PFAM: Phage integrase YP_004161235.1 InterPro IPR010093; KEGG: bfs:BF1137 transposase; SPTR: uncharacterized protein; TIGRFAM: DNA binding domain protein, excisionase; TIGRFAM: DNA binding domain, excisionase YP_004161236.1 COGs: COG0486 GTPase; InterProIPR004520: IPR005225: IPR001806: IPR018948: IPR 002917; KEGG: bth:BT_4551 tRNA modification GTPase TrmE; PFAM: GTP-binding protein TrmE-like; GTP-binding protein HSR1-related; SPTR: tRNA modification GTPase mnmE; TIGRFAM: tRNA modification GTPase TrmE; small GTP-binding protein; PFAM: GTPase of unknown function; GTP-binding protein TrmE N-terminus; TIGRFAM: tRNA modification GTPase TrmE; small GTP-binding protein domain YP_004161237.1 COGs: COG2820 Uridine phosphorylase; InterPro IPR000845; KEGG: bfr:BF1175 purine nucleoside phosphorylase II; PFAM: purine or other phosphorylase 1; SPTR: Purine nucleoside phosphorylase II; PFAM: phosphorylase superfamily YP_004161238.1 COGs: COG4864 conserved hypothetical protein; InterPro IPR001107; KEGG: bfs:BF1143 hypothetical protein; PFAM: band 7 protein; SPTR: uncharacterized protein; PFAM: SigmaW regulon antibacterial YP_004161239.1 InterPro IPR002810; KEGG: bth:BT_4556 hypothetical protein; PFAM: protein of unknown function DUF107; SPTR: uncharacterized protein; PFAM: NfeD-like YP_004161240.1 InterPro IPR013026: IPR011659; KEGG: bfs:BF1145 hypothetical protein; PFAM: hypothetical protein; SPTR: uncharacterized protein YP_004161241.1 COGs: COG0037 ATPase of the PP-loop superfamily protein implicated in cell cycle control; InterPro IPR012089: IPR011063; KEGG: bfs:BF1146 hypothetical protein; PFAM: PP-loop domain protein; SPTR: uncharacterized protein; PFAM: PP-loop family YP_004161242.1 COGs: COG3169 conserved hypothetical protein; InterPro IPR007437; KEGG: bfs:BF1147 hypothetical protein; PFAM: protein of unknown function DUF486; SPTR: uncharacterized protein; PFAM: Protein of unknown function, DUF486 YP_004161243.1 COGs: COG1477 Membrane-associated lipoprotein involved in thiamine biosynthesis; InterPro IPR003374; KEGG: bfr:BF1182 thiamine biosynthesis lipoprotein ApbE precursor; PFAM: ApbE family lipoprotein; SPTR: uncharacterized protein; PFAM: ApbE family YP_004161244.1 COGs: COG1971 membrane protein; InterPro IPR003810; KEGG: bfs:BF1149 transmembrane protein; PFAM: protein of unknown function DUF204; SPTR: uncharacterized protein; PFAM: Domain of unknown function DUF YP_004161245.1 KEGG: bfr:BF1184 hypothetical protein; SPTR: uncharacterized protein YP_004161246.1 KEGG: bfs:BF1151 hypothetical protein; SPTR: uncharacterized protein YP_004161247.1 COGs: COG0463 glycosyltransferase involved in cell wall biogenesis; InterPro IPR001173; KEGG: bth:BT_4564 glycosyltransferase; PFAM: glycosyl transferase 2; SPTR: uncharacterized protein; PFAM: glycosyl transferase 2 YP_004161248.1 KEGG: bfr:BF1187 hypothetical protein; SPTR: uncharacterized protein YP_004161249.1 InterPro IPR011123: IPR000792; KEGG: phe:Phep_3632 two component regulator three Y domain protein; PFAM: two component regulator three Y domain-containing protein; regulatory protein LuxR; SMART: regulatory protein LuxR; SPTR: uncharacterized protein; PFAM: Y_Y_Y domain YP_004161250.1 InterPro IPR012910: IPR000531; KEGG: pru:PRU_1950 receptor antigen RagA; PFAM: TonB-dependent receptor plug; TonB-dependent receptor; SPTR: uncharacterized protein; PFAM: TonB dependent receptor; TonB-dependent Receptor Plug Domain YP_004161251.1 InterPro IPR012944; KEGG: pru:PRU_1951 lipoprotein; PFAM: RagB/SusD domain protein; SPTR: uncharacterized protein; PFAM: SusD family YP_004161252.1 InterPro IPR000601; KEGG: pru:PRU_1952 hypothetical protein; SPTR: uncharacterized protein YP_004161253.1 COGs: COG2273 Beta-glucanase/Beta-glucan synthetase; InterPro IPR000757; KEGG: pru:PRU_1953 family 16 glycosyl hydrolase; PFAM: glycoside hydrolase 16; PRIAM: Licheninase; SPTR: uncharacterized protein; PFAM: glycosyl hydrolases family 16 YP_004161254.1 COGs: COG1472 Beta-glucosidase-related glycosidase; InterPro IPR001764: IPR002772: IPR019800: IPR001901; KEGG: hau:Haur_3463 glycoside hydrolase 3 protein; PFAM: glycoside hydrolase 3; SPTR: uncharacterized protein; PFAM: glycosyl hydrolase 3 C terminal domain; glycosyl hydrolase 3 N terminal domain YP_004161255.1 COGs: COG0148 Enolase; InterPro IPR000941: IPR020811: IPR020810: IPR020809; KEGG: bfs:BF1155 phosphopyruvate hydratase; PFAM: Enolase-like; PRIAM: phosphopyruvate hydratase; SPTR: Enolase; TIGRFAM: enolase; PFAM: Enolase, N-terminal domain; Enolase, C-terminal TIM barrel domain; TIGRFAM: phosphopyruvate hydratase YP_004161256.1 COGs: COG0239 Integral membrane protein possibly involved in chromosome condensation; InterPro IPR003691; KEGG: bfs:BF1157 camphor resistance protein CrcB; PFAM: Camphor resistance CrcB protein; SPTR: CrcB protein; TIGRFAM: CrcB protein; PFAM: CrcB-like protein; TIGRFAM: crcB protein YP_004161257.1 COGs: COG0642 Signal transduction histidine kinase; InterPro IPR004358: IPR005467: IPR003661: IPR003594; KEGG: pdi:BDI_0806 two-component system sensor histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: uncharacterized protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain YP_004161258.1 InterPro IPR019563; KEGG: bth:BT_4581 alpha-glucosidase; PFAM: glycoside hydrolase 97; SPTR: uncharacterized protein; PFAM: glycoside hydrolase 97 YP_004161259.1 COGs: COG0034 Glutamine phosphoribosylpyrophosphate amidotransferase; InterPro IPR017932: IPR005854; KEGG: bth:BT_4582 amidophosphoribosyltransferase precursor; PRIAM: Amidophosphoribosyltransferase; SPTR: Amidophosphoribosyl-transferase; PFAM: phosphoribosyl transferase domain; TIGRFAM: amidophosphoribosyltransferase YP_004161260.1 COGs: COG2195 Di- and tripeptidase; InterPro IPR010161: IPR002933: IPR011650: IPR001261; KEGG: bfs:BF1289 peptidase T; PFAM: peptidase dimerisation domain protein; peptidase M20; PRIAM: Tripeptide aminopeptidase; SPTR: peptidase T; TIGRFAM: peptidase T; PFAM: peptidase M20/M25/M40; peptidase dimerisation domain; TIGRFAM: peptidase T YP_004161261.1 COGs: COG0404 glycine cleavage system T protein (aminomethyltransferase); InterPro IPR006223: IPR006222: IPR013977; KEGG: bfs:BF1290 glycine cleavage system aminomethyltransferase T; PFAM: glycine cleavage T protein (aminomethyl transferase); glycine cleavage T-protein barrel; SPTR: Aminomethyltransferase; TIGRFAM: glycine cleavage system T protein; PFAM: glycine cleavage T-protein C-terminal barrel domain; Aminomethyltransferase folate-binding domain; TIGRFAM: glycine cleavage system T protein YP_004161262.1 COGs: COG5009 Membrane carboxypeptidase/penicillin-binding protein; InterPro IPR001264: IPR001460: IPR000634; KEGG: pru:PRU_0704 penicillin-binding protein 1A; PFAM: glycosyl transferase 51; penicillin-binding protein transpeptidase; PRIAM: peptidoglycan glycosyltransferase; SPTR: uncharacterized protein; PFAM: Penicillin binding protein transpeptidase domain; Transglycosylase YP_004161263.1 COGs: COG0254 Ribosomal protein L31; InterPro IPR002150; KEGG: bvu:BVU_1670 50S ribosomal protein L31 type B; PFAM: ribosomal protein L31; SPTR: 50S ribosomal protein L31; TIGRFAM: ribosomal protein L31; PFAM: Ribosomal protein L31; TIGRFAM: ribosomal protein L31 YP_004161264.1 InterPro IPR005135; KEGG: bfs:BF3139 hypothetical protein; PFAM: Endonuclease/exonuclease/phosphatase; SPTR: uncharacterized protein; PFAM: Endonuclease/Exonuclease/phosphatase YP_004161265.1 COGs: COG0191 Fructose/tagatose bisphosphate aldolase; InterPro IPR000771: IPR011289; KEGG: bth:BT_1691 fructose-bisphosphate aldolase; PFAM: ketose-bisphosphate aldolase class-II; PRIAM: Fructose-bisphosphate aldolase; SPTR: Fructose-1,6-bisphosphate aldolase, class II; TIGRFAM: fructose-1,6-bisphosphate aldolase, class II; ketose-bisphosphate aldolase; PFAM: Fructose-bisphosphate aldolase class-II; TIGRFAM: ketose-bisphosphate aldolases; fructose-1,6-bisphosphate aldolase, class II, various bacterial and amitochondriate protist YP_004161266.1 COGs: COG0366 glycosidase; InterPro IPR015171: IPR006047: IPR019492: IPR006589; KEGG: bfs:BF3134 alpha-amylase precursor; PFAM: alpha amylase catalytic region; Cyclomaltodextrinase; Cyclo-malto-dextrinase-like; SMART: alpha amylase catalytic sub domain; SPTR: uncharacterized protein; PFAM: Cyclomaltodextrinase, N-terminal; Alpha amylase, catalytic domain; Cyclo-malto-dextrinase C-terminal domain YP_004161267.1 InterPro IPR019734: IPR013026: IPR001440; KEGG: bth:BT_1690 TPR domain-containing protein; PFAM: hypothetical protein; SPTR: TPR-domain-containing protein; PFAM: Tetratricopeptide repeat YP_004161268.1 COGs: COG1883 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase beta subunit; InterPro IPR005661; KEGG: bvu:BVU_2488 oxaloacetate decarboxylase beta chain; PFAM: Na+transporting methylmalonyl-CoA/oxaloacetate decarboxylase beta subunit; PRIAM: Glutaconyl-CoA decarboxylase; SPTR: Oxaloacetate decarboxylase subunit beta; TIGRFAM: sodium ion-translocating decarboxylase, beta subunit; PFAM: subunit; TIGRFAM: sodium ion-translocating decarboxylase, beta subunit YP_004161269.1 COGs: COG4770 Acetyl/propionyl-CoA carboxylase alpha subunit; InterPro IPR000089: IPR001882; KEGG: bth:BT_1688 biotin carboxyl carrier protein (BccP); PFAM: biotin/lipoyl attachment domain-containing protein; SPTR: uncharacterized protein; PFAM: Biotin-requiring enzyme YP_004161270.1 KEGG: bvu:BVU_2490 hypothetical protein; SPTR: uncharacterized protein; PFAM: Oxaloacetate decarboxylase, gamma chain YP_004161271.1 COGs: COG4799 Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta); InterPro IPR011762: IPR011763: IPR000022; KEGG: bth:BT_1686 propionyl-CoA carboxylase beta chain; PFAM: carboxyl transferase; SPTR: uncharacterized protein; PFAM: Carboxyl transferase domain YP_004161272.1 InterPro IPR017515: IPR004360; KEGG: bvu:BVU_2492 lactoyl gluthatione lyase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; SPTR: methylmalonyl-CoA epimerase; TIGRFAM: methylmalonyl-CoA epimerase; PFAM: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; TIGRFAM: methylmalonyl-CoA epimerase YP_004161273.1 InterPro IPR018201; KEGG: wri:WRi_008170 methyltransferase, SPTR: uncharacterized protein YP_004161274.1 KEGG: bfs:BF1160 hypothetical protein; SPTR: Conserved hypothetical exported protein YP_004161275.1 COGs: COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)protein; InterPro IPR006665; KEGG: bfs:BF3180 hypothetical protein; PFAM: OmpA/MotB domain protein; SPTR: uncharacterized protein; PFAM: OmpA family YP_004161276.1 COGs: COG0475 Kef-type K+ transport systems membrane components; InterPro IPR006037: IPR006153; KEGG: bfs:BF1293 Na+/H+ antiporter; PFAM: sodium/hydrogen exchanger; TrkA-C domain protein; SPTR: uncharacterized protein; PFAM: TrkA-C domain; Sodium/hydrogen exchanger family; TC 2.A.37 YP_004161277.1 COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683: IPR004104; KEGG: bfs:BF1650 GFO/IDH/MocA family oxidoreductase; PFAM: oxidoreductase domain protein; Oxidoreductase domain; SPTR: uncharacterized protein; PFAM: Oxidoreductase, NAD-binding Rossmann fold; Oxidoreductase, C-terminal alpha/beta domain YP_004161278.1 COGs: COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog); InterPro IPR002942; KEGG: bfs:BF1162 ribosome-associated heat shock protein; PFAM: RNA-binding S4 domain protein; SMART: RNA-binding S4 domain protein; SPTR: uncharacterized protein; PFAM: S4 domain YP_004161279.1 COGs: COG0193 peptidyl-tRNA hydrolase; InterPro IPR001328: IPR018171; KEGG: bfs:BF1163 peptidyl-tRNA hydrolase; PFAM: peptidyl-tRNA hydrolase; PRIAM: Aminoacyl-tRNA hydrolase; SPTR: peptidyl-tRNA hydrolase; TIGRFAM: peptidyl-tRNA hydrolase; PFAM: peptidyl-tRNA hydrolase; TIGRFAM: peptidyl-tRNA hydrolase YP_004161280.1 COGs: COG1825 Ribosomal protein L25 (general stress protein Ctc); InterPro IPR001021: IPR020055; KEGG: bfs:BF1164 50S ribosomal protein L25/general stress protein Ctc; PFAM: Ribosomal protein L25-like; SPTR: 50S ribosomal protein L25; TIGRFAM: ribosomal 5S rRNA E-loop binding protein Ctc/L25/TL5; PFAM: Ribosomal L25p family; TIGRFAM: ribosomal protein L25, Ctc-form YP_004161281.1 InterPro IPR006628; KEGG: bfs:BF1165 hypothetical protein; SMART: PUR-alpha/beta/gamma DNA/RNA-binding; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF3276) YP_004161282.1 SPTR: uncharacterized protein YP_004161283.1 COGs: COG0781 Transcription termination factor; InterPro IPR011605: IPR006027; KEGG: bfs:BF1166 N utilization substance protein; PFAM: NusB/RsmB/TIM44; SPTR: uncharacterized protein; TIGRFAM: transcription antitermination factor NusB; PFAM: NusB family; TIGRFAM: transcription antitermination factor NusB YP_004161284.1 COGs: COG1862 Preprotein translocase subunit YajC; InterPro IPR003849; KEGG: bfs:BF1167 hypothetical protein; PFAM: YajC family protein; SPTR: uncharacterized protein; TIGRFAM: preprotein translocase, YajC subunit; PFAM: Preprotein translocase subunit; TIGRFAM: preprotein translocase, YajC subunit YP_004161285.1 InterPro IPR012505; KEGG: bfs:BF1168 hypothetical protein; PFAM: YbbR family protein; SPTR: uncharacterized protein; PFAM: YbbR-like protein YP_004161286.1 COGs: COG0237 Dephospho-CoA kinase; InterPro IPR001977; KEGG: bth:BT_4594 dephospho-CoA kinase; PFAM: Dephospho-CoA kinase; PRIAM: Dephospho-CoA kinase; SPTR: uncharacterized protein; TIGRFAM: dephospho-CoA kinase; PFAM: Dephospho-CoA kinase; TIGRFAM: dephospho-CoA kinase YP_004161287.1 KEGG: bth:BT_4595 hypothetical protein; SPTR: uncharacterized protein YP_004161288.1 COGs: COG0542 ATPase with chaperone activity ATP-binding subunit; InterProIPR017730: IPR001270: IPR004176: IPR003959: IPR 013093: IPR019489: IPR003593: IPR018368; KEGG: bth:BT_4597 endopeptidase Clp ATP-binding chain B; PFAM: ATPase AAA; AAA ATPase central domain protein; Clp domain protein; Clp ATPase-like; SMART: AAA ATPase; SPTR: uncharacterized protein; TIGRFAM: ATP-dependent chaperone ClpB; PFAM: AAA domain (Cdc48 subfamily); C-terminal, D2-small domain, of ClpB protein; Clp amino terminal domain; ATPase associated with various cellular activities (AAA); TIGRFAM: ATP-dependent chaperone ClpB YP_004161289.1 KEGG: bfs:BF1173 hypothetical protein; SPTR: uncharacterized protein YP_004161290.1 COGs: COG0583 Transcriptional regulator; InterPro IPR000847: IPR005119; KEGG: bfs:BF1174 transcriptional regulator; PFAM: LysR substrate-binding; regulatory protein LysR; SPTR: uncharacterized protein; PFAM: LysR substrate binding domain; Bacterial regulatory helix-turn-helix protein, lysR family YP_004161291.1 COGs: COG2855 membrane protein; InterPro IPR018383; KEGG: bfr:BF1208 hypothetical protein; PFAM: Uncharacterised protein family UPF0324; SPTR: uncharacterized protein; PFAM: Conserved hypothetical protein 698; TIGRFAM: conserved hypothetical integral membrane protein YP_004161292.1 InterPro IPR006645; KEGG: bfs:BF1709 LPS-related regulatory protein; PFAM: NGN domain-containing protein; SPTR: uncharacterized protein; PFAM: Transcription termination factor nusG YP_004161293.1 KEGG: tte:TTE2118 hypothetical protein; SPTR: uncharacterized protein YP_004161294.1 InterPro IPR001387; KEGG: bfr:BF1192 hypothetical protein; PFAM: hypothetical protein; SPTR: uncharacterized protein; PFAM: Helix-turn-helix YP_004161295.1 COGs: COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog; InterPro IPR014284: IPR007627: IPR013249; KEGG: bfs:BF1178 RNA polymerase ECF-type sigma factor; PFAM: Sigma-70 region 4 type 2; sigma-70 region 2 domain protein; SPTR: uncharacterized protein; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family YP_004161296.1 KEGG: bfr:BF1210 hypothetical protein; SPTR: uncharacterized protein YP_004161297.1 KEGG: bfr:BF1209 hypothetical protein; SPTR: uncharacterized protein YP_004161298.1 COGs: COG0468 RecA/RadA recombinase; InterProIPR013765: IPR001553: IPR020588: IPR020587: IPR 003593: IPR020584; KEGG: bth:BT_4610 recombinase A; PFAM: RecA domain protein; SMART: AAA ATPase; SPTR: Protein recA; TIGRFAM: recA protein; PFAM: recA bacterial DNA recombination protein; TIGRFAM: protein RecA YP_004161299.1 COGs: COG1225 Peroxiredoxin; InterPro IPR017936: IPR000866; KEGG: bfr:BF1214 bacterioferritin co-migratory protein; PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; PRIAM: Peroxiredoxin; SPTR: uncharacterized protein; PFAM: AhpC/TSA family YP_004161300.1 COGs: COG1748 Saccharopine dehydrogenase and related protein; InterPro IPR005097; KEGG: bvu:BVU_2379 hypothetical protein; PFAM: Saccharopine dehydrogenase; SPTR: Saccharopine dehydrogenase; PFAM: Saccharopine dehydrogenase YP_004161301.1 COGs: COG3187 Heat shock protein; InterPro IPR005184; KEGG: bfs:BF1184 hypothetical protein; PFAM: protein of unknown function DUF306 Meta and HslJ; SPTR: uncharacterized protein; PFAM: META domain YP_004161302.1 COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterPro IPR000595; KEGG: bvu:BVU_0342 regulatory protein; PFAM: cyclic nucleotide-binding; SPTR: uncharacterized protein; PFAM: Cyclic nucleotide-binding domain YP_004161303.1 COGs: COG0534 Na+-driven multidrug efflux pump; InterPro IPR002528; KEGG: bvu:BVU_0343 transmembrane cation efflux protein; PFAM: multi antimicrobial extrusion protein MatE; SPTR: uncharacterized protein; manually curated; PFAM: MatE; TIGRFAM: efflux protein, MATE family YP_004161304.1 COGs: COG0443 Molecular chaperone; InterPro IPR012725: IPR001023: IPR013126: IPR018181; KEGG: bfs:BF1189 molecular chaperone DnaK; PFAM: Heat shock protein 70; SPTR: Chaperone protein dnaK; TIGRFAM: chaperone protein DnaK; PFAM: Hsp70 protein; TIGRFAM: chaperone protein DnaK YP_004161305.1 InterPro IPR010093; KEGG: bth:BT_4616 hypothetical protein; SPTR: uncharacterized protein; TIGRFAM: DNA binding domain protein, excisionase; PFAM: Bacteriophage Lambda NinG protein; TIGRFAM: DNA binding domain, excisionase YP_004161306.1 COGs: COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog; InterPro IPR014284: IPR014327: IPR007627: IPR013249; KEGG: bth:BT_4402 RNA polymerase ECF-type sigma factor; PFAM: Sigma-70 region 4 type 2; sigma-70 region 2 domain protein; SPTR: RNA polymerase ECF-type sigma factor; TIGRFAM: RNA polymerase sigma-70 factor; RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; RNA polymerase sigma-70 factor, Bacteroides expansion family 1 YP_004161307.1 KEGG: dfe:Dfer_5410 transposase IS116/IS110/IS902 family protein; SPTR: uncharacterized protein YP_004161308.1 COGs: COG3712 Fe2+-dicitrate sensor membrane component; InterPro IPR012373: IPR006860; KEGG: bth:BT_4403 anti-sigma factor; PFAM: FecR protein; SPTR: uncharacterized protein; PFAM: FecR protein YP_004161309.1 COGs: COG1629 Outer membrane receptor protein mostly Fe transport; InterPro IPR011662: IPR012910: IPR000531: IPR002114; KEGG: bth:BT_4404 hypothetical protein; PFAM: TonB-dependent receptor; TonB-dependent receptor plug; Secretin/TonB short domain; SPTR: uncharacterized protein; PFAM: TonB-dependent Receptor Plug Domain; Secretin and TonB N terminus short domain YP_004161310.1 KEGG: bth:BT_4405 hypothetical protein; SPTR: uncharacterized protein YP_004161311.1 KEGG: bth:BT_4406 hypothetical protein; SPTR: Secreted endoglycosidase YP_004161312.1 InterPro IPR013728; KEGG: bth:BT_4407 hypothetical protein; PFAM: domain of unknown function DUF1735; SPTR: uncharacterized protein; PFAM: Domain of unknown function (DUF1735) YP_004161314.1 KEGG: bth:BT_2317 hypothetical protein; SPTR: uncharacterized protein YP_004161315.1 KEGG: bth:BT_2318 hypothetical protein; SPTR: uncharacterized protein YP_004161316.1 KEGG: bth:BT_2319 hypothetical protein; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF3575); OmpA family YP_004161317.1 COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR018060: IPR000005; KEGG: bth:BT_2320 transcription regulator; PFAM: helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: Transcription regulator; PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family YP_004161318.1 COGs: COG4974 Site-specific recombinase XerD; InterPro IPR002104; KEGG: bth:BT_2322 integrase; PFAM: integrase; SPTR: uncharacterized protein; PFAM: Phage integrase YP_004161320.1 KEGG: cim:CIMG_06225 hypothetical protein; SPTR: glycyl-tRNA synthetase YP_004161321.1 KEGG: bth:BT_2316 hypothetical protein; SPTR: uncharacterized protein YP_004161322.1 KEGG: bfr:BF2863 hypothetical protein; SPTR: uncharacterized protein YP_004161323.1 InterPro IPR004256; KEGG: bfr:BF2824 ATPase; PFAM: DUF234 DEXX-box ATPase; SPTR: uncharacterized protein; PFAM: Archaeal ATPase; Archaea bacterial proteins of unknown function YP_004161324.1 KEGG: bfr:BF2819 hypothetical protein; SPTR: uncharacterized protein YP_004161325.1 COGs: COG0561 hydrolase of the HAD superfamily; InterProIPR000150: IPR006379: IPR003736: IPR013200: IPR 006683; KEGG: bth:BT_4699 hydrolase, haloacid dehalogenase-like hydrolase; PFAM: Haloacid dehalogenase domain protein hydrolase type 3; thioesterase superfamily protein; SPTR: uncharacterized protein; TIGRFAM: Cof-like hydrolase; HAD-superfamily hydrolase, subfamily IIB; PFAM: Thioesterase superfamily; haloacid dehalogenase-like hydrolase; TIGRFAM: uncharacterized domain 1; Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily; HAD-superfamily hydrolase, subfamily IIB YP_004161326.1 KEGG: tad:TRIADDRAFT_62071 hypothetical protein; SPTR: Predicted protein YP_004161327.1 COGs: COG4206 Outer membrane cobalamin receptor protein; InterPro IPR012910: IPR000531; KEGG: pdi:BDI_3417 vitamin B12 receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor plug; SPTR: uncharacterized protein; manually curated; PFAM: TonB dependent receptor; TonB-dependent Receptor Plug Domain YP_004161328.1 KEGG: pdi:BDI_3418 hypothetical protein; SPTR: uncharacterized protein YP_004161329.1 COGs: COG0614 ABC-type Fe3+-hydroxamate transport system periplasmic component; InterPro IPR002491; KEGG: bvu:BVU_2055 iron-related ABC transport periplasmic binding protein; PFAM: periplasmic binding protein; SPTR: uncharacterized protein; PFAM: Periplasmic binding protein YP_004161330.1 COGs: COG0609 ABC-type Fe3+-siderophore transport system permease component; InterPro IPR000522; KEGG: bvu:BVU_2054 iron(III) ABC transporter permease; PFAM: transport system permease; SPTR: uncharacterized protein; PFAM: FecCD transport family YP_004161331.1 InterPro IPR002104; KEGG: bvu:BVU_2525 tyrosine type site-specific recombinase; PFAM: integrase; SPTR: uncharacterized protein; PFAM: Phage integrase YP_004161332.1 KEGG: avi:Avi_5260 hypothetical protein; SPTR: uncharacterized protein YP_004161333.1 KEGG: lpc:LPC_1855 hypothetical protein; SPTR: uncharacterized protein YP_004161334.1 KEGG: bth:BT_4642 hypothetical protein; SPTR: uncharacterized protein YP_004161335.1 COGs: COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog; InterPro IPR014284: IPR014327: IPR007627: IPR013249; KEGG: bth:BT_4643 RNA polymerase ECF-type sigma factor; PFAM: Sigma-70 region 4 type 2; sigma-70 region 2 domain protein; SPTR: RNA polymerase ECF-type sigma factor; TIGRFAM: RNA polymerase sigma-70 factor; RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; RNA polymerase sigma-70 factor, Bacteroides expansion family 1 YP_004161336.1 COGs: COG3712 Fe2+-dicitrate sensor membrane component; InterPro IPR006860; KEGG: bth:BT_4644 anti-sigma factor; PFAM: FecR protein; SPTR: uncharacterized protein; PFAM: FecR protein YP_004161337.1 KEGG: bth:BT_4645 hypothetical protein; SPTR: uncharacterized protein YP_004161338.1 KEGG: bfs:BF0576 hypothetical protein; SPTR: uncharacterized protein YP_004161339.1 COGs: COG1350 alternative tryptophan synthase beta-subunit (paralog of TrpB); InterPro IPR006316: IPR001926: IPR006653; KEGG: bfs:BF1192 tryptophan synthase subunit beta; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; SPTR: Pyridoxal-phosphate dependent TrpB-like enzyme; TIGRFAM: pyridoxal-phosphate dependent TrpB-like enzyme; manually curated; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: pyridoxal-phosphate dependent TrpB-like enzyme YP_004161340.1 COGs: COG0168 Trk-type K+ transport systems membrane components; InterPro IPR003445; KEGG: bth:BT_4665 K+ uptake protein; PFAM: cation transporter; PRIAM: H(+)-transporting two-sector ATPase; SPTR: uncharacterized protein; PFAM: Cation transport protein YP_004161341.1 COGs: COG0569 K+ transport systems NAD-binding component; InterPro IPR003148: IPR006037; KEGG: bth:BT_4666 K+ uptake system protein; PFAM: TrkA-N domain protein; SPTR: uncharacterized protein; PFAM: TrkA-N domain YP_004161342.1 KEGG: bth:BT_2534 hypothetical protein; SPTR: uncharacterized protein; TIGRFAM: DNA-binding protein, histone-like YP_004161343.1 InterPro IPR005902; KEGG: bth:BT_2538 hypothetical protein; SPTR: uncharacterized protein; TIGRFAM: DNA-binding protein; TIGRFAM: DNA-binding protein, histone-like YP_004161344.1 KEGG: bfs:BF1212 hypothetical protein; SPTR: uncharacterized protein YP_004161345.1 KEGG: tca:660908 similar to CG15744-PA; SPTR: uncharacterized protein YP_004161346.1 KEGG: bth:BT_4674 hypothetical protein; SPTR: uncharacterized protein; manually curated YP_004161347.1 COGs: COG1760 L-serine deaminase; InterPro IPR005131: IPR005130; KEGG: bfs:BF1216 L-serine dehydratase; PFAM: serine dehydratase alpha chain; serine dehydratase beta chain; PRIAM: L-serine ammonia-lyase; SPTR: uncharacterized protein; PFAM: Serine dehydratase alpha chain; Serine dehydratase beta chain; TIGRFAM: L-serine dehydratase, iron-sulfur-dependent, single chain form YP_004161348.1 COGs: COG1193 Mismatch repair ATPase (MutS family); InterPro IPR002625: IPR005747: IPR000432: IPR007696; KEGG: bfr:BF1267 DNA mismatch repair protein MutS; PFAM: Smr protein/MutS2; DNA mismatch repair protein MutS domain protein; SMART: DNA mismatch repair protein MutS domain protein; MutS III domain protein; Smr protein/MutS2; SPTR: uncharacterized protein; PFAM: MutS domain V; Smr domain; TIGRFAM: MutS2 family protein YP_004161349.1 COGs: COG4974 Site-specific recombinase XerD; InterPro IPR002104; KEGG: bvu:BVU_2470 transposase; PFAM: integrase; SPTR: uncharacterized protein; PFAM: Phage integrase YP_004161350.1 KEGG: tde:TDE0367 hypothetical protein; SPTR: uncharacterized protein YP_004161351.1 KEGG: bth:BT_2279 ribose phosphate pyrophosphokinase; SPTR: uncharacterized protein; PFAM: phosphoribosyl transferase domain YP_004161352.1 InterPro IPR000305; KEGG: cro:ROD_20541 hypothetical protein; PFAM: excinuclease ABC subunit C; SPTR: uncharacterized protein; PFAM: GIY-YIG catalytic domain YP_004161353.1 InterPro IPR010093; KEGG: bvu:BVU_2478 hypothetical protein; SPTR: uncharacterized protein; TIGRFAM: DNA binding domain protein, excisionase; TIGRFAM: DNA binding domain, excisionase YP_004161354.1 KEGG: bth:BT_2332 hypothetical protein; SPTR: uncharacterized protein YP_004161355.1 KEGG: bfr:BF0145 hypothetical protein; SPTR: uncharacterized protein YP_004161356.1 KEGG: pdi:BDI_1003 hypothetical protein; SPTR: uncharacterized protein; TIGRFAM: DNA-binding protein, histone-like YP_004161357.1 KEGG: pgn:PGN_1291 conserved hypothetical protein related to phage; SPTR: uncharacterized protein YP_004161358.1 KEGG: bfr:BF0106 hypothetical protein; SPTR: uncharacterized protein YP_004161359.1 KEGG: bth:BT_2283 hypothetical protein; SPTR: Ctn001 YP_004161360.1 COGs: COG4474 conserved hypothetical protein; KEGG: bth:BT_2282 hypothetical protein; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF1273) YP_004161361.1 KEGG: pgn:PGN_1295 hypothetical protein; SPTR: uncharacterized protein; manually curated YP_004161362.1 InterPro IPR001387; KEGG: bvu:BVU_3740 hypothetical protein; PFAM: hypothetical protein; SMART: hypothetical protein; SPTR: Toxin-antitoxin system, antitoxin component, Xre family; PFAM: Helix-turn-helix YP_004161363.1 COGs: COG0642 Signal transduction histidine kinase; InterPro IPR005467: IPR003594; KEGG: ses:SARI_03149 hypothetical protein; PFAM: ATP-binding region ATPase domain protein; SPTR: uncharacterized protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase YP_004161364.1 KEGG: ses:SARI_03148 hypothetical protein; SPTR: uncharacterized protein YP_004161365.1 InterPro IPR002711: IPR003615; KEGG: ses:SARI_03147 hypothetical protein; PFAM: HNH endonuclease; SMART: HNH nuclease; SPTR: HNH endonuclease domain-containing protein; PFAM: HNH endonuclease YP_004161366.1 InterPro IPR002296: IPR002052; KEGG: wsu:WS1930 hypothetical protein; SPTR: uncharacterized protein; PFAM: N-6 DNA methylase YP_004161367.1 KEGG: edi:EDI_296810 hypothetical protein; SPTR: uncharacterized protein YP_004161368.1 KEGG: lbc:LACBIDRAFT_292160 hypothetical protein; SPTR: uncharacterized protein YP_004161369.1 KEGG: bta:100298387 similar to guanylate binding protein 2; SPTR: uncharacterized protein YP_004161370.1 KEGG: bfs:BF1319 hypothetical protein; SPTR: uncharacterized protein YP_004161371.1 COGs: COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog; InterPro IPR014284: IPR007627: IPR013249; KEGG: bfs:BF1320 RNA polymerase ECF-type sigma factor; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; SPTR: uncharacterized protein; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family YP_004161372.1 KEGG: bfs:BF1321 hypothetical protein; SPTR: uncharacterized protein YP_004161373.1 COGs: COG1180 Pyruvate-formate lyase-activating enzyme; InterPro IPR012838: IPR007197: IPR001989; KEGG: bth:BT_4737 pyruvate formate-lyase activating enzyme; PFAM: radical SAM protein; PRIAM: [formate-C-acetyltransferase]-activating enzyme; SPTR: Pyruvate formate-lyase 1-activating enzyme; TIGRFAM: pyruvate formate-lyase activating enzyme; PFAM: Radical SAM superfamily; TIGRFAM: pyruvate formate-lyase 1-activating enzyme YP_004161374.1 COGs: COG1882 Pyruvate-formate lyase; InterPro IPR005949: IPR001150: IPR004184: IPR019777; KEGG: bfs:BF1323 formate acetyltransferase 1; PFAM: pyruvate formate-lyase PFL; formate C-acetyltransferase glycine radical; PRIAM: formate C-acetyltransferase; SPTR: uncharacterized protein; TIGRFAM: formate acetyltransferase; PFAM: glycine radical; Pyruvate formate lyase; TIGRFAM: formate acetyltransferase 1 YP_004161375.1 KEGG: lma:LmjF15.0900 hypothetical protein; SPTR: uncharacterized protein YP_004161376.1 KEGG: bfr:BF3849 hypothetical protein; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF3575) YP_004161377.1 InterPro IPR014941; KEGG: bfr:BF3848 hypothetical protein; PFAM: protein of unknown function DUF1812; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF1812) YP_004161378.1 KEGG: bfr:BF3847 hypothetical protein; SPTR: uncharacterized protein YP_004161379.1 KEGG: bfr:BF3846 hypothetical protein; SPTR: uncharacterized protein YP_004161380.1 InterPro IPR005902; KEGG: bfr:BF3676 non-specific DNA binding protein; SPTR: uncharacterized protein; TIGRFAM: DNA-binding protein; TIGRFAM: DNA-binding protein, histone-like YP_004161381.1 KEGG: bfs:BF1388 hypothetical protein; SPTR: uncharacterized protein; PFAM: Chagasin family peptidase inhibitor I42 YP_004161382.1 InterPro IPR017441; KEGG: bfr:BF3845 hypothetical protein; SPTR: uncharacterized protein YP_004161383.1 KEGG: ddi:DDB_G0274605 Ras guanine nucleotide exchange factor; SPTR: Ras guanine nucleotide exchange factor R YP_004161384.1 InterPro IPR018534; KEGG: bfr:BF3844 hypothetical protein; PFAM: Tetracycline regulation of excision, RteC; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF2589); RteC protein YP_004161385.1 COGs: COG4804 conserved hypothetical protein; InterPro IPR009362; KEGG: hap:HAPS_0836 hypothetical protein; PFAM: protein of unknown function DUF1016; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF1016) YP_004161386.1 COGs: COG0863 DNA modification methylase; InterPro IPR001091: IPR002941: IPR002052: IPR005829; KEGG: cyc:PCC7424_3051 DNA methylase N-4/N-6 domain protein; PFAM: DNA methylase N-4/N-6 domain protein; SPTR: DNA methylase N-4/N-6 domain protein; PFAM: DNA methylase YP_004161387.1 COGs: COG2843 protein of poly-gamma-glutamate biosynthesis (capsule formation); InterPro IPR019079; KEGG: bfr:BF3221 capsule biosynthesis protein; PFAM: Capsule synthesis protein, CapA; SPTR: uncharacterized protein; PFAM: Bacterial capsule synthesis protein PGA_cap YP_004161388.1 COGs: COG0190 5 10-methylene-tetrahydrofolate dehydrogenase/methenyl tetrahydrofolate cyclohydrolase; InterPro IPR000672: IPR020630: IPR020631: IPR020867; KEGG: bth:BT_1607 bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/5,10-methylene-tetrahydrofolate cyclohydrolase; PFAM: Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain; Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; PRIAM: methenyltetrahydrofolate cyclohydrolase; SPTR: Bifunctional protein folD; PFAM: Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain; Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain YP_004161389.1 COGs: COG0541 Signal recognition particle GTPase; InterProIPR004780: IPR013822: IPR000897: IPR004125: IPR 003593; KEGG: bth:BT_1601 signal recognition protein; PFAM: GTP-binding signal recognition particle SRP54 G- domain; GTP-binding signal recognition particle SRP54 helical bundle; Signal peptide binding (SRP54) M- domain protein; SMART: AAA ATPase; SPTR: uncharacterized protein; TIGRFAM: signal recognition particle protein; PFAM: SRP54-type protein, GTPase domain; SRP54-type protein, helical bundle domain; Signal peptide binding domain; TIGRFAM: signal recognition particle protein YP_004161390.1 COGs: COG1158 Transcription termination factor; InterProIPR004665: IPR011112: IPR011113: IPR000194: IPR 011129: IPR003593; KEGG: bfr:BF3213 transcription termination factor Rho; PFAM: H+transporting two-sector ATPase alpha/beta subunit central region; Rho termination factor RNA-binding; Rho termination factor domain protein; SMART: Cold shock protein; AAA ATPase; SPTR: Transcription termination factor Rho; TIGRFAM: transcription termination factor Rho; manually curated; PFAM: Rho termination factor, N-terminal domain; Rho termination factor, RNA-binding domain; ATP synthase alpha/beta family, nucleotide-binding domain; TIGRFAM: transcription termination factor Rho YP_004161391.1 COGs: COG0037 ATPase of the PP-loop superfamily protein implicated in cell cycle control; InterPro IPR012795: IPR012796: IPR011063: IPR003006; KEGG: bfr:BF1416 cell-cycle protein; PFAM: PP-loop domain protein; SPTR: uncharacterized protein; TIGRFAM: tRNA(Ile)-lysidine synthetase; PFAM: PP-loop family; B3/4 domain; TIGRFAM: tRNA(Ile)-lysidine synthetase, C-terminal domain; tRNA(Ile)-lysidine synthetase, N-terminal domain YP_004161392.1 COGs: COG0370 Fe2+ transport system protein B; InterProIPR005225: IPR003373: IPR007167: IPR002917: IPR 011619: IPR011642: IPR011640; KEGG: bvu:BVU_2887 iron transport, fusion membrane protein; PFAM: Ferrous iron transport protein B domain-containing protein; GTP-binding protein HSR1-related; FeoA family protein; nucleoside recognition domain protein; Ferrous iron transport B domain-containing protein; SPTR: uncharacterized protein; TIGRFAM: ferrous iron transport protein B; small GTP-binding protein; PFAM: FeoA domain; Ferrous iron transport protein B; Ferrous iron transport protein B C terminus; Nucleoside recognition; TIGRFAM: ferrous iron transporter FeoB; small GTP-binding protein domain YP_004161393.1 COGs: COG1225 Peroxiredoxin; InterPro IPR017936: IPR013740; KEGG: bfs:BF1378 hypothetical protein; PFAM: Redoxin domain protein; SPTR: uncharacterized protein; PFAM: Redoxin YP_004161394.1 InterPro IPR013216; KEGG: bfs:BF1380 methyltransferase; PFAM: methyltransferase type 11; SPTR: uncharacterized protein YP_004161395.1 KEGG: bfs:BF1381 hypothetical protein; SPTR: uncharacterized protein YP_004161396.1 InterPro IPR004360; KEGG: bth:BT_1580 lactoylglutathione lyase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; SPTR: uncharacterized protein; PFAM: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily YP_004161397.1 KEGG: bfs:BF1383 hypothetical protein; SPTR: uncharacterized protein YP_004161398.1 COGs: COG2220 Zn-dependent hydrolase of the beta-lactamase fold; InterPro IPR018252; KEGG: bfs:BF1384 hypothetical protein; SPTR: uncharacterized protein YP_004161399.1 COGs: COG1052 Lactate dehydrogenase and related dehydrogenase; InterPro IPR006139: IPR006140; KEGG: bfs:BF1389 D-lactate dehydrogenase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; SPTR: uncharacterized protein; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain YP_004161400.1 KEGG: bvu:BVU_2212 outer membrane protein precursor; SPTR: uncharacterized protein YP_004161401.1 COGs: COG1738 conserved hypothetical protein; InterPro IPR003744; KEGG: bfr:BF1464 hypothetical protein; PFAM: protein of unknown function DUF165; SPTR: uncharacterized protein; TIGRFAM: conserved hypothetical protein; PFAM: Uncharacterized ACR, YhhQ family COG1738; TIGRFAM: conserved hypothetical integral membrane protein YP_004161402.1 COGs: COG0603 PP-loop superfamily ATPase; InterPro IPR004479: IPR018317; KEGG: bth:BT_1566 aluminum resistance protein; PFAM: Queuosine synthesis-like; SPTR: uncharacterized protein; TIGRFAM: exsB protein; PFAM: ExsB; TIGRFAM: exsB protein YP_004161403.1 COGs: COG0780 Enzyme related to GTP cyclohydrolase I; InterPro IPR016856: IPR020602; KEGG: bth:BT_1564 7-cyano-7-deazaguanine reductase; PFAM: GTP cyclohydrolase I/Nitrile oxidoreductase; PRIAM: PreQ(1) synthase; SPTR: NADPH-dependent 7-cyano-7-deazaguanine reductase; TIGRFAM: 7-cyano-7-deazaguanine reductase; PFAM: GTP cyclohydrolase I; TIGRFAM: 7-cyano-7-deazaguanine reductase YP_004161404.1 COGs: COG0148 Enolase; InterPro IPR000941: IPR020811: IPR020810: IPR020809; KEGG: bth:BT_4572 phosphopyruvate hydratase; PFAM: Enolase-like; PRIAM: phosphopyruvate hydratase; SPTR: Enolase; TIGRFAM: enolase; PFAM: Enolase, N-terminal domain; Enolase, C-terminal TIM barrel domain; TIGRFAM: phosphopyruvate hydratase YP_004161405.1 KEGG: bfs:BF2704 hypothetical protein; SPTR: uncharacterized protein YP_004161406.1 KEGG: bfs:BF1027 iron-regulated transmembrane protein; SPTR: uncharacterized protein; PFAM: PepSY-associated TM helix YP_004161407.1 KEGG: bfs:BF2166 hypothetical protein; SPTR: uncharacterized protein YP_004161408.1 KEGG: bfs:BF2165 lipoprotein; SPTR: uncharacterized protein YP_004161409.1 COGs: COG4771 Outer membrane receptor for ferrienterochelin and colicins; InterPro IPR012910: IPR000531; KEGG: bfr:BF2102 TonB-dependent outer membrane receptor protein; PFAM: TonB-dependent receptor; TonB-dependent receptor plug; SPTR: TonB-dependent outer membrane receptor protein; PFAM: TonB-dependent Receptor Plug Domain; TonB dependent receptor YP_004161410.1 KEGG: bfs:BF2163 lipoprotein; SPTR: uncharacterized protein YP_004161411.1 KEGG: bfr:BF2100 hypothetical protein; SPTR: uncharacterized protein YP_004161412.1 KEGG: bfs:BF2161 hypothetical protein; SPTR: uncharacterized protein YP_004161413.1 KEGG: bfr:BF2098 hypothetical protein; SPTR: uncharacterized protein YP_004161414.1 COGs: COG1132 ABC-type multidrug transport system ATPase and permease components; InterProIPR003439: IPR017940: IPR001140: IPR003593: IPR 017871; KEGG: bfs:BF2172 transport-related membrane protein; PFAM: ABC transporter related; ABC transporter transmembrane region; SMART: AAA ATPase; SPTR: ABC transporter ATP-binding protein; PFAM: ABC transporter; ABC transporter transmembrane region YP_004161415.1 COGs: COG2226 methylase involved in ubiquinone/menaquinone biosynthesis; InterPro IPR013216; KEGG: bfs:BF1007 methyltransferase; PFAM: methyltransferase type 11; SPTR: uncharacterized protein; PFAM: methyltransferase domain YP_004161416.1 COGs: COG1132 ABC-type multidrug transport system ATPase and permease components; InterProIPR003439: IPR017940: IPR001140: IPR003593: IPR 017871; KEGG: bfs:BF2171 transport-related membrane protein; PFAM: ABC transporter related; ABC transporter transmembrane region; SMART: AAA ATPase; SPTR: transport-related membrane protein; PFAM: ABC transporter transmembrane region; ABC transporter YP_004161417.1 KEGG: fsu:Fisuc_1741 hypothetical protein; SPTR: uncharacterized protein YP_004161418.1 KEGG: pgi:PG1179 hypothetical protein; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF1329) YP_004161419.1 COGs: COG1033 exporter of the RND superfamily protein; InterPro IPR000731; KEGG: fsu:Fisuc_1739 exporter of the RND superfamily protein-like protein; SPTR: uncharacterized protein; PFAM: MMPL family YP_004161421.1 COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterPro IPR000595: IPR001808; KEGG: bvu:BVU_2982 transcriptional regulator; PFAM: cyclic nucleotide-binding; SMART: cyclic nucleotide-binding; regulatory protein Crp; SPTR: uncharacterized protein; PFAM: Cyclic nucleotide-binding domain YP_004161422.1 COGs: COG1151 6Fe-6S prismane cluster-containing protein; InterPro IPR004137: IPR010048; KEGG: bvu:BVU_2981 hydroxylamine reductase; PFAM: Prismane; SPTR: Hydroxylamine reductase; TIGRFAM: hybrid cluster protein; PFAM: Prismane/CO dehydrogenase; TIGRFAM: hydroxylamine reductase YP_004161423.1 COGs: COG0524 Sugar kinase ribokinase; InterPro IPR011611; KEGG: bvu:BVU_2607 ribokinase; PFAM: PfkB domain protein; SPTR: uncharacterized protein; PFAM: pfkB family carbohydrate kinase YP_004161424.1 COGs: COG2220 Zn-dependent hydrolase of the beta-lactamase fold; KEGG: pdi:BDI_3557 outer membrane protein; SPTR: uncharacterized protein; PFAM: Metallo-beta-lactamase superfamily YP_004161425.1 KEGG: bfs:BF2377 hypothetical protein; SPTR: uncharacterized protein YP_004161426.1 COGs: COG1154 Deoxyxylulose-5-phosphate synthase; InterPro IPR005475: IPR005476; KEGG: bth:BT_1403 1-deoxy-D-xylulose-5-phosphate synthase; PFAM: Transketolase central region; Transketolase domain-containing protein; PRIAM: 1-deoxy-D-xylulose-5-phosphate synthase; SPTR: 1-deoxy-D-xylulose-5-phosphate synthase; PFAM: Dehydrogenase E1 component; Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain; TIGRFAM: 1-deoxy-D-xylulose-5-phosphate synthase YP_004161427.1 SPTR: uncharacterized protein YP_004161428.1 COGs: COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog; InterPro IPR007627: IPR013249: IPR014284: IPR014327; KEGG: bfr:BF3609 RNA polymerase ECF-type sigma factor; PFAM: Sigma-70 region 4 type 2; sigma-70 region 2 domain protein; SPTR: RNA polymerase sigma-70 factor; TIGRFAM: RNA polymerase sigma-70 factor; RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; RNA polymerase sigma-70 factor, Bacteroides expansion family 1 YP_004161429.1 COGs: COG3712 Fe2+-dicitrate sensor membrane component; InterPro IPR006860: IPR012373; KEGG: bfs:BF3411 regulatory protein; PFAM: FecR protein; SPTR: Sigma factor regulatory protein, FecR/PupR family; PFAM: FecR protein YP_004161430.1 COGs: COG1629 Outer membrane receptor protein mostly Fe transport; InterPro IPR011662: IPR012910: IPR000531: IPR001564; KEGG: bfs:BF3412 outer membrane protein Omp117; PFAM: TonB-dependent receptor plug; Secretin/TonB short domain; TonB-dependent receptor; SPTR: outer membrane protein; PFAM: TonB dependent receptor; TonB-dependent Receptor Plug Domain; Secretin and TonB N terminus short domain YP_004161431.1 KEGG: bfr:BF3612 hypothetical protein; SPTR: uncharacterized protein YP_004161432.1 InterPro IPR001579; KEGG: bfs:BF1312 endo-beta-N-acetylglucosaminidase; SPTR: Endo-beta-N-acetylglucosaminidase F2 (Mannosyl-glycoprotein endo-beta-N-acetyl-glucosaminidase F2) YP_004161433.1 InterPro IPR013728; KEGG: bfs:BF3415 lipoprotein; PFAM: domain of unknown function DUF1735; SPTR: uncharacterized protein; PFAM: Domain of unknown function (DUF1735) YP_004161434.1 InterPro IPR000421; KEGG: coc:Coch_1391 hypothetical protein; PFAM: coagulation factor 5/8 type domain protein; SPTR: lipoprotein; PFAM: F5/8 type C domain YP_004161436.1 COGs: COG0788 formyltetrahydrofolate hydrolase; InterPro IPR004810: IPR002912: IPR002376; KEGG: bth:BT_1381 formyltetrahydrofolate deformylase; PFAM: formyl transferase domain protein; amino acid-binding ACT domain protein; SPTR: uncharacterized protein; TIGRFAM: formyltetrahydrofolate deformylase; PFAM: ACT domain; formyl transferase; TIGRFAM: formyltetrahydrofolate deformylase YP_004161437.1 COGs: COG0118 Glutamine amidotransferase; InterPro IPR000991: IPR010139: IPR017926: IPR016226; KEGG: bfr:BF3055 imidazole glycerol phosphate synthase subunit HisH; PFAM: glutamine amidotransferase class-I; SPTR: Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; TIGRFAM: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; PFAM: Glutamine amidotransferase class-I; TIGRFAM: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit YP_004161438.1 COGs: COG0106 phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase; InterPro IPR006062; KEGG: bfs:BF2890 imidazole-4-carboxamide isomerase; PFAM: histidine biosynthesis protein; SPTR: uncharacterized protein; PFAM: Histidine biosynthesis protein; TIGRFAM: phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase YP_004161439.1 COGs: COG0107 Imidazoleglycerol-phosphate synthase; InterPro IPR006062: IPR004651; KEGG: bth:BT_1378 imidazole glycerol phosphate synthase subunit HisF; PFAM: histidine biosynthesis protein; SPTR: uncharacterized protein; TIGRFAM: imidazoleglycerol phosphate synthase, cyclase subunit; PFAM: Histidine biosynthesis protein; TIGRFAM: imidazoleglycerol phosphate synthase, cyclase subunit YP_004161440.1 COGs: COG0139 phosphoribosyl-AMP cyclohydrolase; InterPro IPR002496: IPR021130: IPR008179; KEGG: bfs:BF2888 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase; PFAM: phosphoribosyl-AMP cyclohydrolase; phosphoribosyl-ATP pyrophosphohydrolase-like; SPTR: uncharacterized protein; TIGRFAM: phosphoribosyl-ATP diphosphatase; PFAM: phosphoribosyl-ATP pyrophosphohydrolase; phosphoribosyl-AMP cyclohydrolase; TIGRFAM: phosphoribosyl-ATP pyrophosphohydrolase YP_004161441.1 COGs: COG2884 ATPase involved in cell division; InterPro IPR003593: IPR003439: IPR017871; KEGG: bth:BT_1376 ATP-binding protein involved in cell division; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: uncharacterized protein; PFAM: ABC transporter YP_004161442.1 COGs: COG0527 Aspartokinase; InterPro IPR001048: IPR001341: IPR018042; KEGG: bfs:BF2886 aspartokinase III; PFAM: aspartate/glutamate/uridylate kinase; PRIAM: Aspartate kinase; SPTR: Aspartokinase; TIGRFAM: aspartate kinase; PFAM: Amino acid kinase; TIGRFAM: aspartate kinase YP_004161443.1 COGs: COG0019 Diaminopimelate decarboxylase; InterPro IPR000183: IPR002986; KEGG: bfr:BF3049 diaminopimelate decarboxylase; PFAM: Orn/DAP/Arg decarboxylase 2; SPTR: Diaminopimelate decarboxylase; TIGRFAM: diaminopimelate decarboxylase; PFAM: Pyridoxal-dependent decarboxylase, C-terminal sheet domain; Pyridoxal-dependent decarboxylase, pyridoxal binding domain; TIGRFAM: diaminopimelate decarboxylase YP_004161444.1 COGs: COG1528 Ferritin-like protein; InterPro IPR008331: IPR009040; KEGG: bth:BT_1373 ferritin A; PFAM: Ferritin Dps family protein; PRIAM: Ferroxidase; SPTR: uncharacterized protein; PFAM: Ferritin-like domain YP_004161445.1 COGs: COG0156 7-keto-8-aminopelargonate synthetase; InterPro IPR004839: IPR011282; KEGG: bfs:BF2864 2-amino-3-ketobutyrate coenzyme A ligase; PFAM: aminotransferase class I and II; PRIAM: glycine C-acetyltransferase; SPTR: 2-amino-3-ketobutyrate coenzyme A ligase; TIGRFAM: 2-amino-3-ketobutyrate coenzyme A ligase; PFAM: Aminotransferase class I and II; TIGRFAM: 8-amino-7-oxononanoate synthase; 2-amino-3-ketobutyrate coenzyme A ligase YP_004161446.1 COGs: COG0451 Nucleoside-diphosphate-sugar epimerase; InterPro IPR001509; KEGG: bfs:BF2863 epimerase; PFAM: NAD-dependent epimerase/dehydratase; PRIAM: L-threonine 3-dehydrogenase; SPTR: uncharacterized protein; PFAM: NAD dependent epimerase/dehydratase YP_004161447.1 KEGG: bth:BT_1369 hypothetical protein; SPTR: uncharacterized protein YP_004161448.1 COGs: COG0812 UDP-N-acetylmuramate dehydrogenase; InterPro IPR006094: IPR011601: IPR003170: IPR016166; KEGG: bfr:BF2985 UDP-N-acetylenolpyruvoylglucosamine reductase; PFAM: UDP-N-acetylenolpyruvoylglucosamine reductase domain-containing protein; FAD linked oxidase domain protein; PRIAM: UDP-N-acetylmuramate dehydrogenase; SPTR: uncharacterized protein; TIGRFAM: UDP-N-acetylenolpyruvoylglucosamine reductase; PFAM: FAD binding domain; UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; TIGRFAM: UDP-N-acetylenolpyruvoylglucosamine reductase YP_004161449.1 COGs: COG1235 Metal-dependent hydrolase of the beta-lactamase superfamily I; KEGG: bfr:BF2984 hydrolase; SPTR: uncharacterized protein; PFAM: Metallo-beta-lactamase superfamily YP_004161450.1 KEGG: bfs:BF2859 hypothetical protein; SPTR: uncharacterized protein YP_004161451.1 KEGG: bfs:BF2858 hypothetical protein; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF3127) YP_004161452.1 COGs: COG0592 DNA polymerase sliding clamp subunit (PCNA homolog); InterPro IPR001001; KEGG: bth:BT_1364 DNA polymerase III, beta chain; PFAM: DNA polymerase III beta chain; PRIAM: DNA-directed DNA polymerase; SMART: DNA polymerase III beta chain; SPTR: DNA polymerase III, beta subunit; TIGRFAM: DNA polymerase III, beta subunit; PFAM: DNA polymerase III beta subunit, C-terminal domain; DNA polymerase III beta subunit, N-terminal domain; DNA polymerase III beta subunit, central domain; TIGRFAM: DNA polymerase III, beta subunit YP_004161453.1 COGs: COG0847 DNA polymerase III epsilon subunit and related 3'-5' exonuclease; InterPro IPR006055: IPR013520; KEGG: bfs:BF2856 DNA polymerase III epsilon chain; PFAM: Exonuclease RNase T and DNA polymerase III; SMART: Exonuclease; SPTR: uncharacterized protein; PFAM: Exonuclease YP_004161454.1 COGs: COG0452 phosphopantothenoylcysteine synthetase/decarboxylase; InterPro IPR003382: IPR007085: IPR005252; KEGG: bfs:BF2855 DNA/pantothenate metabolism flavoprotein; PFAM: flavoprotein; DNA/pantothenate metabolism flavoprotein domain protein; PRIAM: phosphopantothenate--cysteine ligase; SPTR: phosphopantothenoylcysteine decarboxylase/phosphopantothenate-cysteine ligase; TIGRFAM: phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; PFAM: DNA / pantothenate metabolism flavoprotein; Flavoprotein; TIGRFAM: phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase, prokaryotic YP_004161455.1 COGs: COG0497 ATPase involved in DNA repair; InterPro IPR003395: IPR004604; KEGG: bfr:BF2978 DNA repair protein RecN; PFAM: SMC domain protein; SPTR: DNA repair protein RecN; TIGRFAM: DNA repair protein RecN; PFAM: RecF/RecN/SMC N terminal domain; TIGRFAM: DNA repair protein RecN YP_004161456.1 COGs: COG0566 rRNA methylase; InterPro IPR013123: IPR001537: IPR004441; KEGG: bth:BT_1360 tRNA/rRNA methyltransferase; PFAM: tRNA/rRNA methyltransferase (SpoU); RNA 2-O ribose methyltransferase substrate binding; SPTR: uncharacterized protein; TIGRFAM: RNA methyltransferase, TrmH family, group 3; PFAM: SpoU rRNA methylase; RNA 2'-O ribose methyltransferase substrate binding; TIGRFAM: rRNA methylase, , group 3 YP_004161457.1 InterPro IPR019734: IPR001440: IPR013026; KEGG: bfr:BF2976 TPR repeat-containing protein; PFAM: hypothetical protein; SPTR: uncharacterized protein YP_004161458.1 COGs: COG0251 translation initiation inhibitor yjgF family; InterPro IPR006175: IPR006056: IPR019897; KEGG: bth:BT_1336 translation initiation inhibitor; PFAM: Endoribonuclease L-PSP; SPTR: uncharacterized protein; TIGRFAM: endoribonuclease L-PSP; PFAM: Endoribonuclease L-PSP; TIGRFAM: endoribonuclease L-PSP YP_004161459.1 COGs: COG0285 Folylpolyglutamate synthase; InterPro IPR013221: IPR001645: IPR018109; KEGG: bfs:BF2850 folylpolyglutamate synthase; PFAM: Mur ligase middle domain protein; PRIAM: Tetrahydrofolate synthase; SPTR: uncharacterized protein; TIGRFAM: FolC bifunctional protein; PFAM: Mur ligase middle domain; TIGRFAM: folylpolyglutamate synthase/dihydrofolate synthase YP_004161460.1 COGs: COG1875 ATPase related to phosphate starvation-inducible protein PhoH; InterPro IPR006596: IPR003714; KEGG: bfs:BF2849 PhoH-like protein; PFAM: PhoH family protein; SMART: Nucleotide binding protein PINc; SPTR: uncharacterized protein; PFAM: PhoH-like protein YP_004161461.1 COGs: COG1086 nucleoside-diphosphate sugar epimerase; InterPro IPR003869; KEGG: bfs:BF2848 capsular polysaccharide biosynthesis protein; PFAM: polysaccharide biosynthesis protein CapD; SPTR: uncharacterized protein; PFAM: polysaccharide biosynthesis protein YP_004161462.1 COGs: COG0167 Dihydroorotate dehydrogenase; InterPro IPR012135; KEGG: bth:BT_1333 dihydroorotate dehydrogenase 2; PFAM: dihydroorotate oxidase; SPTR: uncharacterized protein; PFAM: Dihydroorotate dehydrogenase YP_004161463.1 COGs: COG0325 enzyme with a TIM-barrel fold; InterPro IPR001608: IPR011078; KEGG: bth:BT_1332 hypothetical protein; PFAM: alanine racemase; SPTR: YggS family pyridoxal phosphate enzyme; PFAM: Alanine racemase, N-terminal domain; TIGRFAM: pyridoxal phosphate enzyme, YggS family YP_004161464.1 KEGG: bfs:BF2824 hypothetical protein; SPTR: uncharacterized protein YP_004161465.1 COGs: COG1961 Site-specific recombinase DNA invertase Pin homologs; InterPro IPR006119: IPR006118; KEGG: bfs:BF2779 multiple promoter invertase; PFAM: Resolvase domain; SPTR: uncharacterized protein; PFAM: Resolvase, N terminal domain YP_004161466.1 COGs: COG2077 Peroxiredoxin; InterPro IPR013740: IPR017936: IPR018219; KEGG: bth:BT_1329 thiol peroxidase; PFAM: Redoxin domain protein; SPTR: uncharacterized protein; PFAM: Redoxin YP_004161467.1 COGs: COG0586 membrane-associated protein; InterPro IPR015414; KEGG: bfs:BF2775 hypothetical protein; PFAM: SNARE associated Golgi protein; SPTR: uncharacterized protein; PFAM: SNARE associated Golgi protein YP_004161468.1 InterPro IPR019734: IPR001440: IPR013026; KEGG: bfs:BF2774 hypothetical protein; PFAM: hypothetical protein; SPTR: uncharacterized protein; PFAM: Tetratricopeptide repeat YP_004161469.1 COGs: COG0008 Glutamyl- and glutaminyl-tRNA synthetase; InterProIPR020060: IPR020058: IPR020059: IPR004514: IPR 001412; KEGG: bth:BT_1325 glutaminyl-tRNA synthetase; PFAM: Glutamyl/glutaminyl-tRNA synthetase, class Ic, catalytic domain; Glutamyl/glutaminyl-tRNA synthetase, class Ic, anti-codon binding domain; SPTR: uncharacterized protein; TIGRFAM: glutaminyl-tRNA synthetase; manually curated; PFAM: tRNA synthetases class I (E and Q), catalytic domain; tRNA synthetases class I (E and Q), anti-codon binding domain; TIGRFAM: glutaminyl-tRNA synthetase YP_004161470.1 COGs: COG0226 ABC-type phosphate transport system periplasmic component; InterPro IPR006059: IPR011862; KEGG: bfs:BF2772 phosphate-related ABC transport system, exported protein; PFAM: extracellular solute-binding protein family 1; SPTR: phosphate ABC transporter; TIGRFAM: phosphate binding protein; TIGRFAM: phosphate binding protein YP_004161471.1 COGs: COG0573 ABC-type phosphate transport system permease component; InterPro IPR000515: IPR011864; KEGG: bth:BT_1323 ABC transporter permease; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: uncharacterized protein; TIGRFAM: phosphate ABC transporter, inner membrane subunit PstC; PFAM: Binding-protein-dependent transport system inner membrane component; TIGRFAM: phosphate ABC transporter, permease PstC; phosphate ABC transporter, permease PstA YP_004161472.1 COGs: COG0581 ABC-type phosphate transport system permease component; InterPro IPR000515: IPR005672: IPR001412; KEGG: bfs:BF2770 phosphate transport system permease; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: phosphate ABC transporter, permease PstA; TIGRFAM: phosphate ABC transporter, inner membrane subunit PstA; PFAM: Binding-protein-dependent transport system inner membrane component; TIGRFAM: phosphate ABC transporter, permease PstA YP_004161473.1 COGs: COG1117 ABC-type phosphate transport system ATPase component; InterProIPR003593: IPR003439: IPR005670: IPR015850: IPR 017871; KEGG: bfs:BF2769 phosphate ABC transporter ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: phosphate ABC transporter, ATP-binding protein; TIGRFAM: phosphate ABC transporter, ATPase subunit; PFAM: ABC transporter; TIGRFAM: phosphate ABC transporter, ATP-binding protein YP_004161474.1 COGs: COG0704 phosphate uptake regulator; InterPro IPR008170; KEGG: bfs:BF2768 phosphate transport chemotaxis-related protein; PFAM: PhoU family protein; SPTR: uncharacterized protein; TIGRFAM: phosphate transport system regulatory protein PhoU; PFAM: PhoU domain; TIGRFAM: phosphate transport system regulatory protein PhoU YP_004161475.1 InterPro IPR010106; KEGG: bth:BT_2030 hypothetical protein; SPTR: uncharacterized protein; TIGRFAM: conserved hypothetical protein ( transposase or invertase) YP_004161476.1 KEGG: bvu:BVU_0898 hypothetical protein; SPTR: uncharacterized protein YP_004161477.1 InterPro IPR018247; KEGG: bth:BT_4224 hypothetical protein; SPTR: uncharacterized protein YP_004161478.1 KEGG: bth:BT_4225 hypothetical protein; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF1812) YP_004161479.1 InterPro IPR014941; KEGG: bth:BT_4226 hypothetical protein; PFAM: protein of unknown function DUF1812; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF1812) YP_004161480.1 KEGG: bth:BT_4227 hypothetical protein; SPTR: uncharacterized protein YP_004161481.1 KEGG: ctt:CtCNB1_4635 hypothetical protein; SPTR: uncharacterized protein YP_004161482.1 KEGG: bth:BT_4233 hypothetical protein; SPTR: uncharacterized protein; PFAM: OmpA family YP_004161483.1 KEGG: bth:BT_4234 hypothetical protein; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF3575) YP_004161485.1 KEGG: bth:BT_4235 hypothetical protein; SPTR: uncharacterized protein YP_004161486.1 COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterProIPR001789: IPR018060: IPR011110: IPR003594: IPR 000005: IPR005467: IPR018062; KEGG: bth:BT_4236 two-component system sensor histidine kinase/response regulator, hybrid ('one-component system'); PFAM: response regulator receiver; ATP-binding region ATPase domain protein; two component regulator propeller; helix-turn-helix- domain containing protein AraC type; SMART: response regulator receiver; Helix-turn-helix, AraC domain; SPTR: uncharacterized protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; two component regulator propeller; Response regulator receiver domain YP_004161487.1 COGs: COG0307 Riboflavin synthase alpha chain; InterPro IPR001783; KEGG: bth:BT_1317 riboflavin synthase subunit alpha; PFAM: Lumazine-binding protein; PRIAM: Riboflavin synthase; SPTR: uncharacterized protein; TIGRFAM: riboflavin synthase, alpha subunit; PFAM: Lumazine binding domain; TIGRFAM: riboflavin synthase, alpha subunit YP_004161488.1 COGs: COG1295 membrane protein; InterPro IPR004664: IPR017039; KEGG: bfr:BF2749 ribonuclease BN; PFAM: ribonuclease BN; SPTR: uncharacterized protein; TIGRFAM: ribonuclease BN; PFAM: Ribonuclease BN-like family; TIGRFAM: YihY family protein (not ribonuclease BN) YP_004161489.1 COGs: COG0791 Cell wall-associated hydrolase (invasion-associated protein); InterPro IPR003646: IPR000064; KEGG: bfr:BF2747 dipeptidyl peptidase VI; PFAM: NLP/P60 protein; SMART: SH3 domain protein; SPTR: uncharacterized protein; PFAM: NlpC/P60 family YP_004161490.1 COGs: COG4948 L-alanine-DL-glutamate epimerase; InterPro IPR013341: IPR013342: IPR006311: IPR017909; KEGG: bfr:BF2746 muconate cycloisomerase; PFAM: Mandelate racemase/muconate lactonizing protein; SPTR: uncharacterized protein; PFAM: Mandelate racemase / muconate lactonizing enzyme, C-terminal domain; Mandelate racemase / muconate lactonizing enzyme, N-terminal domain; TIGRFAM: Tat (twin-arginine translocation) pathway signal sequence YP_004161491.1 COGs: COG1305 Transglutaminase-like protein; InterPro IPR002931; KEGG: bfr:BF2745 cysteine protease; PFAM: transglutaminase; SMART: transglutaminase; SPTR: uncharacterized protein; PFAM: Transglutaminase-like superfamily YP_004161492.1 COGs: COG0265 Trypsin-like serine protease typically periplasmic contain C-terminal PDZ domain; InterPro IPR001478: IPR001940: IPR001254: IPR011782; KEGG: bfs:BF2761 heat shock-related protease; PFAM: peptidase S1 and S6 chymotrypsin/Hap; PRIAM: HtrA2 peptidase; SMART: PDZ/DHR/GLGF domain protein; SPTR: uncharacterized protein; TIGRFAM: protease Do; PFAM: Trypsin; PDZ domain (Also known as DHR or GLGF); TIGRFAM: periplasmic serine protease, Do/DeqQ family YP_004161493.1 COGs: COG0568 DNA-directed RNA polymerase sigma subunit (sigma70/sigma32); InterProIPR000943: IPR007624: IPR009042: IPR014284: IPR 007627: IPR007630; KEGG: bth:BT_1311 RNA polymerase sigma factor RpoD (sigma-A); PFAM: sigma-70 region 4 domain protein; sigma-70 region 2 domain protein; sigma-70 region 3 domain protein; sigma-70 region 1.2; SPTR: uncharacterized protein; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70, region 4; Sigma-70 region 3; Sigma-70 region 2; Sigma-70 factor, region 1.2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family YP_004161494.1 KEGG: bfs:BF2758 hypothetical protein; SPTR: uncharacterized protein YP_004161495.1 InterPro IPR005077; KEGG: bfr:BF2740 clostripain-related protein; PFAM: peptidase C11 clostripain; SPTR: uncharacterized protein; PFAM: Clostripain family YP_004161496.1 COGs: COG0446 NAD(FAD)-dependent dehydrogenase; InterPro IPR001763: IPR013027: IPR004099: IPR001455; KEGG: bvu:BVU_2422 pyridine nucleotide-disulphide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; Rhodanese domain protein; SirA-like domain-containing protein; SMART: Rhodanese domain protein; SPTR: uncharacterized protein; PFAM: Pyridine nucleotide-disulphide oxidoreductase; SirA-like protein; Rhodanese-like domain; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain YP_004161497.1 InterPro IPR000326; KEGG: pdi:BDI_0813 hypothetical protein; PFAM: phosphoesterase PA-phosphatase related; SMART: phosphoesterase PA-phosphatase related; SPTR: uncharacterized protein; PFAM: PAP2 superfamily YP_004161498.1 InterPro IPR000835; KEGG: bvu:BVU_1310 transcriptional regulator; PFAM: regulatory protein MarR; SMART: regulatory protein MarR; SPTR: uncharacterized protein; PFAM: MarR family YP_004161499.1 SPTR: uncharacterized protein YP_004161500.1 InterPro IPR006645; KEGG: bfs:BF0731 transcriptional regulator; PFAM: NGN domain-containing protein; SPTR: transcriptional regulator UpxY homolog; manually curated; PFAM: Transcription termination factor nusG YP_004161501.1 InterPro IPR010570; KEGG: bfs:BF0732 transcriptional regulator; PFAM: protein of unknown function DUF1141; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF1141) YP_004161502.1 COGs: COG1086 nucleoside-diphosphate sugar epimerase; InterPro IPR003869: IPR020025; KEGG: cps:CPS_2092 polysaccharide biosynthesis protein; PFAM: polysaccharide biosynthesis protein CapD; SPTR: uncharacterized protein; TIGRFAM: UDP-N-acetylglucosamine 4,6-dehydratase; PFAM: polysaccharide biosynthesis protein; TIGRFAM: UDP-N-acetylglucosamine 4,6-dehydratase YP_004161503.1 COGs: COG0399 pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; InterPro IPR000653: IPR020026; KEGG: gfo:GFO_2027 SpsC-like DegT/DnrJ/EryC1/StrS family aminotransferase; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; SPTR: uncharacterized protein; TIGRFAM: UDP-4-keto-6-deoxy-N-acetylglucosamine 4-aminotransferase; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; TIGRFAM: UDP-4-keto-6-deoxy-N-acetylglucosamine 4-aminotransferase YP_004161504.1 COGs: COG1083 CMP-N-acetylneuraminic acid synthetase; InterPro IPR003329: IPR020039; KEGG: cat:CA2559_13063 NeuA; PFAM: acylneuraminate cytidylyltransferase; SPTR: uncharacterized protein; TIGRFAM: pseudaminic acid CMP-transferase; PFAM: Cytidylyltransferase; TIGRFAM: pseudaminic acid CMP-transferase YP_004161505.1 KEGG: sli:Slin_0533 hypothetical protein; SPTR: uncharacterized protein YP_004161506.1 COGs: COG1669 nucleotidyltransferase; InterPro IPR002934; KEGG: pdi:BDI_1404 hypothetical protein; PFAM: DNA polymerase beta domain protein region; SPTR: uncharacterized protein; PFAM: Nucleotidyltransferase domain YP_004161507.1 COGs: COG3980 Spore coat polysaccharide biosynthesis protein predicted glycosyltransferase; InterPro IPR020023; KEGG: gfo:GFO_2022 hypothetical protein; SPTR: uncharacterized protein; TIGRFAM: pseudaminic acid biosynthesis-associated protein PseG; TIGRFAM: pseudaminic acid biosynthesis-associated protein PseG YP_004161508.1 COGs: COG0223 methionyl-tRNA formyltransferase; InterPro IPR002376: IPR005793; KEGG: phe:Phep_3943 formyl transferase domain protein; PFAM: formyl transferase domain protein; SPTR: formyl transferase domain protein; PFAM: formyl transferase; formyl transferase, C-terminal domain YP_004161509.1 InterPro IPR011761; KEGG: pdi:BDI_0029 hypothetical protein; SPTR: uncharacterized protein YP_004161510.1 COGs: COG3949 hypothetical protein; KEGG: shi:Shel_21530 hypothetical protein; SPTR: uncharacterized protein YP_004161511.1 KEGG: bmq:BMQ_0201 SH3 domain protein; SPTR: Predicted protein YP_004161512.1 COGs: COG2089 Sialic acid synthase; InterPro IPR013132: IPR013974: IPR020030: IPR006190; KEGG: tmt:Tmath_0718 pseudaminic acid synthase; PFAM: N-acetylneuraminic acid synthase domain; SAF domain protein; PRIAM: N-acetylneuraminate synthase; SPTR: Pseudaminic acid synthase; TIGRFAM: pseudaminic acid synthase; PFAM: SAF domain; NeuB family; TIGRFAM: pseudaminic acid synthase YP_004161513.1 COGs: COG2120 conserved hypothetical protein LmbE homologs; InterPro IPR003737; KEGG: gfo:GFO_2017 hypothetical protein; PFAM: LmbE family protein; SPTR: uncharacterized protein; PFAM: GlcNAc-PI de-N-acetylase YP_004161514.1 InterPro IPR006619: IPR002502; KEGG: bvu:BVU_3916 N-acetylmuramoyl-L-alanine amidase; PFAM: N-acetylmuramoyl-L-alanine amidase 2; SMART: N-acetylmuramoyl-L-alanine amidase 2; Animal peptidoglycan recognition protein PGRP; SPTR: N-acetylmuramoyl-L-alanine amidase; PFAM: N-acetylmuramoyl-L-alanine amidase YP_004161515.1 KEGG: bth:BT_1640 hypothetical protein; SPTR: uncharacterized protein; TIGRFAM: DNA-binding protein, histone-like YP_004161516.1 KEGG: bth:BT_1704 hypothetical protein; SPTR: uncharacterized protein YP_004161517.1 KEGG: bth:BT_1638 hypothetical protein; SPTR: uncharacterized protein YP_004161518.1 InterPro IPR014907; KEGG: bth:BT_1702 hypothetical protein; PFAM: VirE; SPTR: uncharacterized protein; PFAM: VirE N-terminal domain YP_004161520.1 InterPro IPR002934: IPR000489: IPR020606; KEGG: bvu:BVU_2668 hypothetical protein; PFAM: DNA polymerase beta domain protein region; SPTR: Nucleotidyltransferase domain protein; PFAM: Nucleotidyltransferase domain YP_004161521.1 KEGG: hna:Hneap_0241 hypothetical protein; SPTR: Toxin-antitoxin system, antitoxin component family protein YP_004161522.1 InterPro IPR018631: IPR012547; KEGG: bfs:BF2880 hypothetical protein; PFAM: AAA-ATPase-like; protein of unknown function DUF1703; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF1703); Predicted AAA-ATPase YP_004161523.1 InterPro IPR018631: IPR012547; KEGG: bfs:BF2880 hypothetical protein; PFAM: AAA-ATPase-like; protein of unknown function DUF1703; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF1703); Predicted AAA-ATPase YP_004161524.1 InterPro IPR018631: IPR012547; KEGG: bfs:BF2880 hypothetical protein; PFAM: AAA-ATPase-like; protein of unknown function DUF1703; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF1703); Predicted AAA-ATPase YP_004161525.1 KEGG: sli:Slin_3349 hypothetical protein; SPTR: uncharacterized protein YP_004161526.1 KEGG: bvu:BVU_4034 hypothetical protein; SPTR: uncharacterized protein YP_004161527.1 COGs: COG0438 glycosyltransferase; InterPro IPR001296; KEGG: bpy:Bphyt_2105 glycosyl transferase group 1; PFAM: glycosyl transferase group 1; SPTR: glycosyl transferase group 1; PFAM: glycosyl transferases group 1 YP_004161528.1 COGs: COG2244 Membrane protein involved in the export of O-antigen and teichoic acid; InterPro IPR002797; KEGG: bvu:BVU_4032 lipopolysaccharide biosynthesis related polysaccharide transporter/flippase; PFAM: polysaccharide biosynthesis protein; SPTR: uncharacterized protein; PFAM: polysaccharide biosynthesis protein YP_004161529.1 COGs: COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon); InterPro IPR005835: IPR013446; KEGG: pru:PRU_0434 glucose-1-phosphate cytidylyltransferase; PFAM: Nucleotidyl transferase; PRIAM: glucose-1-phosphate cytidylyltransferase; SPTR: uncharacterized protein; TIGRFAM: glucose-1-phosphate cytidylyltransferase; PFAM: Nucleotidyl transferase; TIGRFAM: glucose-1-phosphate cytidylyltransferase YP_004161530.1 COGs: COG0451 Nucleoside-diphosphate-sugar epimerase; InterPro IPR001509: IPR013445; KEGG: bth:BT_1350 CDP-glucose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; SPTR: uncharacterized protein; TIGRFAM: CDP-glucose 4,6-dehydratase; PFAM: NAD dependent epimerase/dehydratase; TIGRFAM: CDP-glucose 4,6-dehydratase YP_004161531.1 KEGG: bth:BT_1349 hypothetical protein; SPTR: uncharacterized protein YP_004161532.1 COGs: COG0451 Nucleoside-diphosphate-sugar epimerase; InterPro IPR001509; KEGG: bth:BT_1348 CDP-abequose synthase; PFAM: NAD-dependent epimerase/dehydratase; SPTR: uncharacterized protein; PFAM: NAD dependent epimerase/dehydratase YP_004161533.1 COGs: COG0463 glycosyltransferase involved in cell wall biogenesis; InterPro IPR001173; KEGG: geo:Geob_1476 glycosyl transferase 2; PFAM: glycosyl transferase 2; SPTR: uncharacterized protein; PFAM: glycosyl transferase 2 YP_004161534.1 InterPro IPR002656; KEGG: pru:PRU_2543 acyltransferase; PFAM: acyltransferase; SPTR: Acyltransferase; PFAM: Acyltransferase YP_004161536.1 KEGG: pin:Ping_1180 hypothetical protein; SPTR: uncharacterized protein; PFAM: Acyltransferase YP_004161537.1 KEGG: bvu:BVU_4021 hypothetical protein; SPTR: uncharacterized protein YP_004161538.1 COGs: COG0438 glycosyltransferase; InterPro IPR001296; KEGG: bvu:BVU_4020 glycosyl transferase; PFAM: glycosyl transferase group 1; SPTR: glycosyltransferase 4; PFAM: glycosyl transferases group 1 YP_004161539.1 COGs: COG0438 glycosyltransferase; InterPro IPR001296; KEGG: ecx:EcHS_A2166 glycosyl transferase, group 1 family protein; PFAM: glycosyl transferase group 1; SPTR: glycosyl transferase, group 1; PFAM: glycosyl transferases group 1 YP_004161540.1 InterPro IPR000276; KEGG: bvu:BVU_4024 hypothetical protein; SPTR: uncharacterized protein; PFAM: IS66 Orf2 like protein YP_004161541.1 SPTR: uncharacterized protein YP_004161542.1 InterPro IPR007712; KEGG: chu:CHU_2622 hypothetical protein; PFAM: plasmid stabilization system; SPTR: uncharacterized protein; manually curated; PFAM: Plasmid stabilisation system protein YP_004161543.1 COGs: COG0451 Nucleoside-diphosphate-sugar epimerase; InterPro IPR001509; KEGG: bfs:BF1564 DNTP-hexose dehydratase-epimerase; PFAM: NAD-dependent epimerase/dehydratase; SPTR: uncharacterized protein; PFAM: NAD dependent epimerase/dehydratase YP_004161544.1 COGs: COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase; InterPro IPR018481; KEGG: bfs:BF1026 phosphate transferase; PFAM: glycosyl transferase, family 4, conserved region; SPTR: uncharacterized protein; PFAM: glycosyl transferase 4 YP_004161545.1 COGs: COG2605 kinase related to galactokinase and mevalonate kinase; InterPro IPR001174: IPR012887: IPR006204: IPR013750; KEGG: bfr:BF2586 bifunctional fucokinase/L-fucose-1-P-guanylyltransferase; PFAM: L-fucokinase; GHMP kinase; GHMP kinase domain protein; PRIAM: Fucokinase; SPTR: Bifunctional fucokinase/L-fucose-1-P-guanylyltransferase; PFAM: GHMP kinases C terminal; GHMP kinases N terminal domain; L-fucokinase YP_004161546.1 COGs: COG1576 conserved hypothetical protein; InterPro IPR003742; KEGG: bth:BT_1562 rRNA large subunit methyltransferase; PFAM: protein of unknown function DUF163; SPTR: Ribosomal RNA large subunit methyltransferase H; PFAM: Predicted SPOUT methyltransferase; TIGRFAM: rRNA large subunit m3Psi methyltransferase RlmH YP_004161547.1 KEGG: bfs:BF1399 hypothetical protein; SPTR: uncharacterized protein YP_004161548.1 COGs: COG0157 Nicotinate-nucleotide pyrophosphorylase; InterPro IPR002638: IPR004393; KEGG: bth:BT_1560 nicotinate-nucleotide pyrophosphorylase; PFAM: Quinolinate phosphoribosyl transferase; PRIAM: Nicotinate-nucleotide diphosphorylase (carboxylating); SPTR: uncharacterized protein; TIGRFAM: nicotinate-nucleotide pyrophosphorylase; PFAM: Quinolinate phosphoribosyl transferase, C-terminal domain; Quinolinate phosphoribosyl transferase, N-terminal domain; TIGRFAM: nicotinate-nucleotide pyrophosphorylase YP_004161549.1 KEGG: bvu:BVU_0010 hypothetical protein; SPTR: uncharacterized protein YP_004161550.1 COGs: COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog; InterPro IPR007627: IPR013249: IPR014284; KEGG: bfs:BF1401 RNA polymerase ECF-type sigma factor; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; SPTR: uncharacterized protein; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family YP_004161551.1 KEGG: bfs:BF1402 hypothetical protein; SPTR: uncharacterized protein YP_004161552.1 KEGG: bfr:BF1472 hypothetical protein; SPTR: uncharacterized protein YP_004161553.1 KEGG: bth:BT_1556 hypothetical protein; SPTR: uncharacterized protein YP_004161554.1 COGs: COG2070 Dioxygenase related to 2-nitropropane dioxygenase; InterPro IPR004136; KEGG: bth:BT_1555 dioxygenase, related to 2-nitropropane dioxygenase; PFAM: 2-nitropropane dioxygenase NPD; SPTR: uncharacterized protein; PFAM: 2-nitropropane dioxygenase YP_004161555.1 COGs: COG0686 Alanine dehydrogenase; InterProIPR007886: IPR007698: IPR008141: IPR008142: IPR 008143; KEGG: bfs:BF1406 alanine dehydrogenase; PFAM: alanine dehydrogenase/PNT domain protein; PRIAM: Alanine dehydrogenase; SPTR: Alanine dehydrogenase; TIGRFAM: alanine dehydrogenase; PFAM: Alanine dehydrogenase/PNT, C-terminal domain; Alanine dehydrogenase/PNT, N-terminal domain; TIGRFAM: alanine dehydrogenase YP_004161556.1 InterPro IPR016047; KEGG: bth:BT_1550 hypothetical protein; PFAM: peptidase M23; SPTR: uncharacterized protein YP_004161557.1 COGs: COG4690 Dipeptidase; InterPro IPR005322; KEGG: bfr:BF1477 secreted peptidase; PFAM: peptidase U34 dipeptidase; SPTR: uncharacterized protein; PFAM: peptidase C69 YP_004161558.1 COGs: COG1109 phosphomannomutase; InterPro IPR005841: IPR005844: IPR005845: IPR016066; KEGG: bvu:BVU_3804 phosphoglucomutase; PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; SPTR: uncharacterized protein; PFAM: phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III; phosphoglucomutase/phosphomannomutase, C-terminal domain; phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I YP_004161559.1 COGs: COG2816 NTP pyrophosphohydrolase containing a Zn-finger probably nucleic-acid-binding; InterPro IPR015375: IPR015376: IPR000086; KEGG: bth:BT_1544 NADH pyrophosphatase; PFAM: NUDIX hydrolase; Zinc ribbon NADH pyrophosphatase; NADH pyrophosphatase-like; PRIAM: NAD(+) diphosphatase; SPTR: uncharacterized protein; PFAM: NADH pyrophosphatase zinc ribbon domain; NUDIX domain YP_004161560.1 KEGG: bth:BT_1424 hypothetical protein; SPTR: uncharacterized protein; TIGRFAM: DNA-binding protein, histone-like YP_004161561.1 SPTR: uncharacterized protein YP_004161562.1 KEGG: bfs:BF2937 hypothetical protein; SPTR: exported protein; PFAM: BNR/Asp-box repeat YP_004161563.1 KEGG: bfs:BF0631 hypothetical protein; SPTR: uncharacterized protein; PFAM: Pregnancy-associated plasma protein-A YP_004161564.1 KEGG: sbp:Sbal223_0744 hypothetical protein; SPTR: uncharacterized protein YP_004161565.1 COGs: COG2425 Uncharacterized protein containing a von Willebrand factor A (vWA) domain; KEGG: bth:BT_0336 hypothetical protein; SPTR: uncharacterized protein YP_004161566.1 COGs: COG0295 Cytidine deaminase; InterPro IPR002125: IPR016192; KEGG: bfr:BF1494 cytidine deaminase; PFAM: CMP/dCMP deaminase zinc-binding; SPTR: uncharacterized protein; PFAM: Cytidine and deoxycytidylate deaminase zinc-binding region; TIGRFAM: cytidine deaminase, homotetrameric YP_004161567.1 COGs: COG1705 Muramidase (flagellum-specific); InterProIPR013338: IPR002482: IPR000423: IPR002901: IPR 018392; KEGG: bth:BT_1538 hemagglutinin; PFAM: Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase; peptidoglycan-binding lysin domain; SMART: Lysozyme subfamily 2; peptidoglycan-binding LysM; SPTR: uncharacterized protein; PFAM: Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase; LysM domain YP_004161568.1 KEGG: phu:Phum_PHUM581880 beta-parvin, SPTR: uncharacterized protein YP_004161569.1 InterPro IPR002842; KEGG: bth:BT_1301 ATP synthase subunit E; PFAM: H+transporting two-sector ATPase E subunit; SPTR: uncharacterized protein; PFAM: ATP synthase B/B' CF(0) YP_004161570.1 KEGG: bfs:BF2748 hypothetical protein; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF2764) YP_004161571.1 COGs: COG1155 H+-ATPase subunit A; InterPro IPR004100: IPR000194: IPR020003; KEGG: bfs:BF2747 V-type ATP synthase subunit A; PFAM: H+transporting two-sector ATPase alpha/beta subunit central region; H+transporting two-sector ATPase alpha/beta subunit domain protein; SPTR: uncharacterized protein; PFAM: ATP synthase alpha/beta family, beta-barrel domain; ATP synthase alpha/beta chain, C terminal domain; ATP synthase alpha/beta family, nucleotide-binding domain YP_004161572.1 COGs: COG1156 H+-ATPase subunit B; InterPro IPR004100: IPR000194; KEGG: bth:BT_1298 V-type ATP synthase subunit B; PFAM: H+transporting two-sector ATPase alpha/beta subunit central region; H+transporting two-sector ATPase alpha/beta subunit domain protein; SPTR: uncharacterized protein; PFAM: ATP synthase alpha/beta family, beta-barrel domain; ATP synthase alpha/beta family, nucleotide-binding domain YP_004161573.1 COGs: COG1394 H+-ATPase subunit D; InterPro IPR002699; KEGG: bfs:BF2745 V-type ATP synthase subunit D; PFAM: H+transporting two-sector ATPase D subunit; SPTR: uncharacterized protein; PFAM: ATP synthase subunit D; TIGRFAM: H(+)-transporting ATP synthase, vacuolar type, subunit D YP_004161574.1 COGs: COG1269 H+-ATPase subunit I; InterPro IPR002490; KEGG: bfs:BF2744 V(vacuolar)-type Na+ ATP synthase subunit I; PFAM: V-type ATPase 116 kDa subunit; SPTR: uncharacterized protein; PFAM: V-type ATPase 116kDa subunit family YP_004161575.1 InterPro IPR002379; KEGG: bfs:BF2743 V(vacuolar)-type Na+-ATP synthase subunit K; PFAM: H+transporting two-sector ATPase C subunit; SPTR: uncharacterized protein; PFAM: ATP synthase subunit C YP_004161576.1 InterPro IPR001296; KEGG: bth:BT_1294 glycogen [starch] synthase, glycosyltransferase; PFAM: glycosyl transferase group 1; PRIAM: glycogen(starch) synthase; SPTR: uncharacterized protein; PFAM: glycogen synthase YP_004161577.1 COGs: COG0058 glucan phosphorylase; InterPro IPR000811: IPR011834; KEGG: bth:BT_1293 alpha-glucan phosphorylase; PFAM: glycosyl transferase 35; PRIAM: phosphorylase; SPTR: uncharacterized protein; TIGRFAM: alpha-glucan phosphorylase; PFAM: Starch synthase catalytic domain; Carbohydrate phosphorylase; Protein of unknown function (DUF3417); TIGRFAM: alpha-glucan phosphorylases YP_004161578.1 InterPro IPR018594; KEGG: bvu:BVU_3218 hypothetical protein; PFAM: Domain of unknown function DUF2023; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF2023) YP_004161579.1 COGs: COG0716 Flavodoxins; InterPro IPR001094: IPR008254: IPR010086; KEGG: bvu:BVU_3217 flavodoxin FldA; PFAM: flavodoxin/nitric oxide synthase; SPTR: Flavodoxin; TIGRFAM: flavodoxin; PFAM: Flavodoxin; TIGRFAM: flavodoxin, long chain YP_004161580.1 KEGG: bth:BT_2481 hypothetical protein; SPTR: uncharacterized protein YP_004161581.1 COGs: COG0588 phosphoglycerate mutase 1; InterPro IPR013078: IPR005952: IPR001345; KEGG: bfs:BF3091 phosphoglyceromutase; PFAM: phosphoglycerate mutase; PRIAM: Bisphosphoglycerate mutase; SPTR: 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase; TIGRFAM: phosphoglycerate mutase 1 family; PFAM: phosphoglycerate mutase; TIGRFAM: phosphoglycerate mutase, BPG-dependent, family 1 YP_004161582.1 KEGG: bth:BT_0973 hypothetical protein; SPTR: uncharacterized protein YP_004161583.1 COGs: COG3610 conserved hypothetical protein; KEGG: bfs:BF2536 hypothetical protein; SPTR: uncharacterized protein YP_004161584.1 COGs: COG2966 conserved hypothetical protein; InterPro IPR010619; KEGG: bfs:BF2537 hypothetical protein; PFAM: protein of unknown function DUF1212; SPTR: uncharacterized protein; manually curated; PFAM: Protein of unknown function (DUF1212) YP_004161585.1 COGs: COG2966 conserved hypothetical protein; InterPro IPR010619; KEGG: pdi:BDI_3405 hypothetical protein; PFAM: protein of unknown function DUF1212; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF1212) YP_004161586.1 COGs: COG0602 Organic radical activating protein; InterPro IPR007197: IPR012837; KEGG: pdi:BDI_3406 hypothetical protein; PFAM: radical SAM protein; SPTR: Anaerobic ribonucleoside-triphosphate reductase activating protein; TIGRFAM: anaerobic ribonucleoside-triphosphate reductase activating protein; PFAM: Radical SAM superfamily; TIGRFAM: anaerobic ribonucleoside-triphosphate reductase activating protein YP_004161587.1 COGs: COG1328 Oxygen-sensitive ribonucleoside-triphosphate reductase; InterPro IPR005144: IPR012833: IPR003006; KEGG: pdi:BDI_3407 anaerobic ribonucleoside triphosphate reductase; PFAM: ATP-cone domain protein; PRIAM: Ribonucleoside-triphosphate reductase; SPTR: Anaerobic ribonucleoside-triphosphate reductase; TIGRFAM: anaerobic ribonucleoside-triphosphate reductase; PFAM: ATP cone domain; TIGRFAM: anaerobic ribonucleoside-triphosphate reductase YP_004161588.1 COGs: COG0620 methionine synthase II (cobalamin-independent); KEGG: bfs:BF2696 hypothetical protein; SPTR: uncharacterized protein YP_004161589.1 COGs: COG1225 Peroxiredoxin; InterPro IPR000866: IPR017936: IPR017937; KEGG: bfs:BF2739 lipoprotein/thioderoxin; PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; SPTR: uncharacterized protein; PFAM: AhpC/TSA family YP_004161590.1 COGs: COG0228 Ribosomal protein S16; InterPro IPR000307; KEGG: bth:BT_1271 30S ribosomal protein S16; PFAM: ribosomal protein S16; SPTR: 30S ribosomal protein S16; TIGRFAM: ribosomal protein S16; PFAM: Ribosomal protein S16; TIGRFAM: ribosomal protein S16 YP_004161591.1 COGs: COG1757 Na+/H+ antiporter; InterPro IPR018461; KEGG: bfr:BF2713 Na+/H+ antiporter; PFAM: Na+/H+ antiporter NhaC-like; SPTR: uncharacterized protein; PFAM: Na+/H+ antiporter family; TC 2.A.35.1.- YP_004161592.1 COGs: COG1879 ABC-type sugar transport system periplasmic component; InterPro IPR000843; KEGG: bfr:BF2701 transcriptional regulator; PFAM: regulatory protein LacI; SMART: regulatory protein LacI; SPTR: uncharacterized protein; PFAM: Bacterial regulatory proteins, lacI family YP_004161593.1 COGs: COG0524 Sugar kinase ribokinase; InterPro IPR011611; KEGG: bvu:BVU_3055 2-dehydro-3-deoxygluconokinase; PFAM: PfkB domain protein; SPTR: uncharacterized protein; PFAM: pfkB family carbohydrate kinase YP_004161594.1 COGs: COG0800 2-keto-3-deoxy-6-phosphogluconate aldolase; InterPro IPR000887; KEGG: bvu:BVU_3056 keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase; PFAM: KDPG and KHG aldolase; SPTR: uncharacterized protein; PFAM: KDPG and KHG aldolase; TIGRFAM: Entner-Doudoroff aldolase YP_004161596.1 COGs: COG1215 glycosyltransferase probably involved in cell wall biogenesis; InterPro IPR001173; KEGG: pdi:BDI_1280 glycosyl transferase; PFAM: glycosyl transferase 2; SPTR: uncharacterized protein; PFAM: glycosyl transferase 2 YP_004161597.1 COGs: COG0463 glycosyltransferase involved in cell wall biogenesis; InterPro IPR001173; KEGG: bth:BT_2876 glycosyltransferase; PFAM: glycosyl transferase 2; SPTR: uncharacterized protein; PFAM: glycosyl transferase 2 YP_004161599.1 KEGG: dfe:Dfer_5326 helix-turn-helix domain-containing protein; SPTR: Toxin-antitoxin system, antitoxin component, Xre family YP_004161600.1 COGs: COG0463 glycosyltransferase involved in cell wall biogenesis; InterPro IPR001173; KEGG: pru:PRU_1758 group 2 family glycosyltransferase; PFAM: glycosyl transferase 2; SPTR: uncharacterized protein; PFAM: glycosyl transferase 2 YP_004161601.1 KEGG: amu:Amuc_0636 flippase; SPTR: uncharacterized protein YP_004161602.1 COGs: COG1216 glycosyltransferase; InterPro IPR001173; KEGG: bfs:BF2059 capsule-related glycosyltransferase; PFAM: glycosyl transferase 2; SPTR: uncharacterized protein; PFAM: glycosyl transferase 2 YP_004161603.1 COGs: COG0463 glycosyltransferase involved in cell wall biogenesis; InterPro IPR001173; KEGG: bfs:BF2056 capsular polysaccharide glycosyltransferase; PFAM: glycosyl transferase 2; SPTR: uncharacterized protein; PFAM: glycosyl transferase 2 YP_004161604.1 KEGG: bfs:BF2054 hypothetical protein; SPTR: uncharacterized protein YP_004161605.1 COGs: COG0438 glycosyltransferase; InterPro IPR001296; KEGG: pdi:BDI_1281 glycosyl transferase; PFAM: glycosyl transferase group 1; SPTR: uncharacterized protein; PFAM: glycosyl transferases group 1 YP_004161606.1 KEGG: pdi:BDI_1280 glycosyl transferase; SPTR: uncharacterized protein YP_004161607.1 KEGG: pdi:BDI_1279 hypothetical protein; SPTR: uncharacterized protein; PFAM: O-Antigen ligase YP_004161608.1 KEGG: pdi:BDI_1278 hypothetical protein; SPTR: uncharacterized protein YP_004161609.1 KEGG: pdi:BDI_1277 hypothetical protein; SPTR: uncharacterized protein; PFAM: Outer membrane efflux protein YP_004161610.1 COGs: COG2148 Sugar transferase involved in lipopolysaccharide synthesis; InterPro IPR003362; KEGG: bth:BT_0523 glycosyltransferase; PFAM: sugar transferase; PRIAM: UDP-phosphate galactose phosphotransferase; SPTR: uncharacterized protein; PFAM: Bacterial sugar transferase YP_004161611.1 COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789; KEGG: bth:BT_0524 two-component system response regulator; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: uncharacterized protein; PFAM: Response regulator receiver domain YP_004161612.1 KEGG: bth:BT_0525 outer membrane protein, function unknown; SPTR: uncharacterized protein YP_004161613.1 COGs: COG0252 L-asparaginase/ Glu-tRNAGln amidotransferase subunit D; InterPro IPR006034: IPR006033: IPR020827; KEGG: bth:BT_0526 L-asparaginase I; PFAM: Asparaginase/glutaminase; SPTR: uncharacterized protein; TIGRFAM: L-asparaginase, type I; PFAM: Asparaginase; TIGRFAM: L-asparaginases, type I YP_004161615.1 COGs: COG0159 Tryptophan synthase alpha chain; InterPro IPR002028: IPR018204; KEGG: bfs:BF2678 tryptophan synthase subunit alpha; PFAM: tryptophan synthase alpha chain; PRIAM: Tryptophan synthase; SPTR: Tryptophan synthase alpha chain; TIGRFAM: tryptophan synthase, alpha subunit; PFAM: Tryptophan synthase alpha chain; TIGRFAM: tryptophan synthase, alpha subunit YP_004161616.1 COGs: COG0135 phosphoribosylanthranilate isomerase; InterPro IPR001240; KEGG: bfr:BF2655 N-(5'-phosphoribosyl)anthranilate isomerase; PFAM: N-(5'phosphoribosyl)anthranilate isomerase (PRAI); PRIAM: phosphoribosylanthranilate isomerase; SPTR: N-(5'-phosphoribosyl)anthranilate isomerase; PFAM: N-(5'phosphoribosyl)anthranilate (PRA) isomerase YP_004161617.1 COGs: COG0134 Indole-3-glycerol phosphate synthase; InterPro IPR013798: IPR001468; KEGG: bfs:BF2676 indole-3-glycerol-phosphate synthase; PFAM: Indole-3-glycerol phosphate synthase; PRIAM: Indole-3-glycerol-phosphate synthase; SPTR: uncharacterized protein; PFAM: Indole-3-glycerol phosphate synthase YP_004161618.1 COGs: COG0547 Anthranilate phosphoribosyltransferase; InterPro IPR017459: IPR000312: IPR005940; KEGG: bvu:BVU_4090 anthranilate phosphoribosyltransferase; PFAM: glycosyl transferase 3; glycosyl transferase, family 3-like; PRIAM: Anthranilate phosphoribosyltransferase; SPTR: Anthranilate phosphoribosyltransferase; TIGRFAM: anthranilate phosphoribosyltransferase; PFAM: glycosyl transferase, a/b domain; glycosyl transferase, helical bundle domain; TIGRFAM: anthranilate phosphoribosyltransferase YP_004161619.1 COGs: COG0512 Anthranilate/para-aminobenzoate synthase component II; InterProIPR006220: IPR011702: IPR001317: IPR000991: IPR 006221: IPR017926; KEGG: bvu:BVU_4089 anthranilate synthase component II; PFAM: glutamine amidotransferase class-I; SPTR: uncharacterized protein; TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: Glutamine amidotransferase class-I; TIGRFAM: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase YP_004161620.1 COGs: COG0147 Anthranilate/para-aminobenzoate synthase component I; InterPro IPR019999: IPR015890: IPR016160; KEGG: bvu:BVU_4088 anthranilate synthase component I; PFAM: Chorismate binding-like; SPTR: Anthranilate synthase component I; PFAM: Anthranilate synthase component I, N terminal region; chorismate binding enzyme YP_004161621.1 COGs: COG0133 Tryptophan synthase beta chain; InterPro IPR001926: IPR006654: IPR006653; KEGG: bth:BT_0533 tryptophan synthase subunit beta; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; SPTR: Tryptophan synthase, beta subunit; TIGRFAM: tryptophan synthase, beta subunit; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: tryptophan synthase, beta subunit YP_004161622.1 KEGG: bfs:BF2667 hypothetical protein; SPTR: uncharacterized protein YP_004161623.1 InterPro IPR008761; KEGG: bfs:BF0523 hypothetical protein; PFAM: peptidase S37 tripeptidyl aminopeptidase; SPTR: uncharacterized protein; PFAM: PS-10 peptidase S37 YP_004161624.1 COGs: COG2814 Arabinose efflux permease; InterPro IPR011701; KEGG: bfr:BF2248 membrane efflux protein; PFAM: major facilitator superfamily MFS_1; SPTR: uncharacterized protein; PFAM: Major Facilitator Superfamily YP_004161625.1 COGs: COG0655 Multimeric flavodoxin WrbA; InterPro IPR005025; KEGG: mru:mru_1609 NADPH-dependent FMN reductase; PFAM: NADPH-dependent FMN reductase; SPTR: Multimeric flavodoxin WrbA; PFAM: NADPH-dependent FMN reductase YP_004161626.1 KEGG: shc:Shell_0866 hypothetical protein; SPTR: uncharacterized protein YP_004161627.1 COGs: COG3968 Uncharacterized protein related to glutamine synthetase; InterPro IPR008146; KEGG: bth:BT_0543 glutamine synthetase; PFAM: glutamine synthetase catalytic region; SPTR: uncharacterized protein; PFAM: Glutamine synthetase, catalytic domain; Glutamine synthetase type III N terminal YP_004161628.1 COGs: COG0004 Ammonia permease; InterPro IPR001905: IPR018047; KEGG: bth:BT_0544 ammonium transporter; PFAM: ammonium transporter; SPTR: uncharacterized protein; TIGRFAM: ammonium transporter; PFAM: Ammonium Transporter Family; TIGRFAM: ammonium transporter; TC 1.A.11 YP_004161629.1 COGs: COG0347 Nitrogen regulatory protein PII; InterPro IPR002187: IPR017918; KEGG: bth:BT_0545 nitrogen regulatory protein P-II; PFAM: nitrogen regulatory protein P-II; SPTR: Nitrogen regulatory protein P-II; PFAM: Nitrogen regulatory protein P-II YP_004161630.1 KEGG: bth:BT_0546 hypothetical protein; SPTR: uncharacterized protein; PFAM: Bacterial protein of unknown function (Gcw_chp) YP_004161631.1 COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004839: IPR019942; KEGG: bth:BT_0547 L,L-diaminopimelate aminotransferase; PFAM: aminotransferase class I and II; SPTR: uncharacterized protein; TIGRFAM: LL-diaminopimelate aminotransferase; PFAM: Aminotransferase class I and II; TIGRFAM: LL-diaminopimelate aminotransferase YP_004161632.1 COGs: COG0253 Diaminopimelate epimerase; InterPro IPR001653: IPR018510; KEGG: bth:BT_0548 diaminopimelate epimerase; PFAM: diaminopimelate epimerase; PRIAM: Diaminopimelate epimerase; SPTR: Diaminopimelate epimerase; TIGRFAM: diaminopimelate epimerase; PFAM: Diaminopimelate epimerase; TIGRFAM: diaminopimelate epimerase YP_004161633.1 COGs: COG1566 Multidrug resistance efflux pump; InterPro IPR006143; KEGG: bth:BT_1536 ABC transporter permease; SPTR: uncharacterized protein; TIGRFAM: efflux transporter, RND family, MFP subunit; TIGRFAM: RND family efflux transporter, MFP subunit YP_004161634.1 COGs: COG0577 ABC-type antimicrobial peptide transport system permease component; InterPro IPR003838; KEGG: bfr:BF1500 hypothetical protein; PFAM: protein of unknown function DUF214; SPTR: uncharacterized protein; PFAM: Predicted permease YP_004161635.1 InterPro IPR003838; KEGG: bfs:BF1434 ABC transporter permease component; PFAM: protein of unknown function DUF214; SPTR: uncharacterized protein; PFAM: Predicted permease YP_004161636.1 COGs: COG1136 ABC-type antimicrobial peptide transport system ATPase component; InterPro IPR003593: IPR003439: IPR017871; KEGG: bvu:BVU_2346 ABC transporter ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: uncharacterized protein; PFAM: ABC transporter YP_004161637.1 COGs: COG0577 ABC-type antimicrobial peptide transport system permease component; InterPro IPR003838; KEGG: pdi:BDI_1956 hypothetical protein; PFAM: protein of unknown function DUF214; SPTR: uncharacterized protein; PFAM: Predicted permease YP_004161638.1 COGs: COG4591 ABC-type transport system involved in lipoprotein release permease component; InterPro IPR003838; KEGG: pdi:BDI_1955 ABC transporter permease; PFAM: protein of unknown function DUF214; SPTR: uncharacterized protein; PFAM: Predicted permease YP_004161639.1 KEGG: bfs:BF1444 hypothetical protein; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF2807) YP_004161640.1 COGs: COG0577 ABC-type antimicrobial peptide transport system permease component; InterPro IPR003838; KEGG: bvu:BVU_2349 hypothetical protein; PFAM: protein of unknown function DUF214; SPTR: uncharacterized protein; PFAM: Predicted permease YP_004161641.1 InterPro IPR003838; KEGG: bvu:BVU_2350 ABC transporter permease; PFAM: protein of unknown function DUF214; SPTR: uncharacterized protein; PFAM: Predicted permease YP_004161642.1 COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661: IPR003594: IPR004358: IPR005467; KEGG: bth:BT_1531 two-component system sensor histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: uncharacterized protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box YP_004161643.1 COGs: COG2407 L-fucose isomerase and related protein; KEGG: bfs:BF1600 hypothetical protein; SPTR: uncharacterized protein; PFAM: L-fucose isomerase, C-terminal domain YP_004161644.1 COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR001176: IPR004839; KEGG: bfs:BF1601 aspartate aminotransferase; PFAM: aminotransferase class I and II; SPTR: uncharacterized protein; PFAM: Aminotransferase class I and II YP_004161645.1 COGs: COG4591 ABC-type transport system involved in lipoprotein release permease component; InterPro IPR003838; KEGG: bfs:BF1602 transmembrane permease; PFAM: protein of unknown function DUF214; SPTR: uncharacterized protein; PFAM: Predicted permease YP_004161646.1 COGs: COG1215 glycosyltransferase probably involved in cell wall biogenesis; InterPro IPR001173; KEGG: bth:BT_1472 hypothetical protein; PFAM: glycosyl transferase 2; SPTR: uncharacterized protein; PFAM: glycosyl transferase 2 YP_004161647.1 COGs: COG0132 Dethiobiotin synthetase; InterPro IPR004472: IPR010916; KEGG: bfs:BF1614 dithiobiotin synthetase; PRIAM: Dethiobiotin synthase; SPTR: Dethiobiotin synthetase; TIGRFAM: dethiobiotin synthase; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain; TIGRFAM: dethiobiotin synthase YP_004161648.1 InterPro IPR013216: IPR011814; KEGG: bfs:BF1615 biotin synthesis-related fusion protein; PFAM: methyltransferase type 11; SPTR: Biotin biosynthesis protein BioC; TIGRFAM: biotin biosynthesis protein BioC; PFAM: methyltransferase domain; TIGRFAM: biotin biosynthesis protein BioC YP_004161649.1 COGs: COG2830 conserved hypothetical protein; InterPro IPR007398; KEGG: bfr:BF1601 biotin synthesis protein BioC; PFAM: protein of unknown function DUF452; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF452) YP_004161650.1 COGs: COG0156 7-keto-8-aminopelargonate synthetase; InterPro IPR004839: IPR004723; KEGG: bth:BT_1443 8-amino-7-oxononanoate synthase; PFAM: aminotransferase class I and II; PRIAM: 8-amino-7-oxononanoate synthase; SPTR: uncharacterized protein; TIGRFAM: 8-amino-7-oxononanoate synthase; PFAM: Aminotransferase class I and II; TIGRFAM: 8-amino-7-oxononanoate synthase YP_004161651.1 COGs: COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; InterProIPR006638: IPR007197: IPR010722: IPR005814: IPR 002684: IPR005815; KEGG: bfs:BF1617 adenosylmethionine-8-amino-7-oxononanoate aminotransferase; PFAM: aminotransferase class-III; biotin and thiamin synthesis associated; radical SAM protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: uncharacterized protein; TIGRFAM: adenosylmethionine-8-amino-7-oxononanoate aminotransferase; biotin synthase; PFAM: Aminotransferase class-III; Radical SAM superfamily; Biotin and Thiamin Synthesis associated domain; TIGRFAM: biotin synthetase; adenosylmethionine-8-amino-7-oxononanoate transaminase YP_004161652.1 KEGG: bfr:BF1604 hypothetical protein; SPTR: uncharacterized protein; manually curated YP_004161653.1 COGs: COG0367 Asparagine synthase (glutamine-hydrolyzing); InterPro IPR000583: IPR001962: IPR006426: IPR017932; KEGG: bth:BT_0551 asparagine synthetase B; PFAM: asparagine synthase; glutamine amidotransferase class-II; PRIAM: Asparagine synthase (glutamine-hydrolyzing); SPTR: Asparagine synthase; TIGRFAM: asparagine synthase (glutamine-hydrolyzing); PFAM: Asparagine synthase; TIGRFAM: asparagine synthase (glutamine-hydrolyzing) YP_004161654.1 COGs: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase; InterPro IPR000759: IPR013027: IPR006005: IPR017896; KEGG: bth:BT_0552 glutamate synthase, small subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: uncharacterized protein; TIGRFAM: glutamate synthase, NADH/NADPH, small subunit; PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: glutamate synthases, NADH/NADPH, small subunit YP_004161655.1 COGs: COG0069 Glutamate synthase domain 2; InterProIPR000583: IPR006982: IPR002932: IPR002489: IPR 017932; KEGG: bth:BT_0553 glutamate synthase, large subunit; PFAM: ferredoxin-dependent glutamate synthase; glutamine amidotransferase class-II; glutamate synthase; glutamate synthase alpha subunit domain protein; PRIAM: Glutamate synthase (ferredoxin); SPTR: uncharacterized protein; PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II YP_004161656.1 COGs: COG0449 glucosamine 6-phosphate synthetase contains amidotransferase and phosphosugar isomerase domains; InterPro IPR000583: IPR017932; KEGG: bth:BT_0554 glucosamine--fructose-6-phosphate aminotransferase; PFAM: glutamine amidotransferase class-II; SPTR: uncharacterized protein; PFAM: Glutamine amidotransferases class-II YP_004161657.1 COGs: COG0034 Glutamine phosphoribosylpyrophosphate amidotransferase; InterPro IPR000583: IPR017932; KEGG: bth:BT_0555 amidophosphoribosyltransferase; PFAM: glutamine amidotransferase class-II; PRIAM: Amidophosphoribosyltransferase; SPTR: uncharacterized protein; PFAM: Glutamine amidotransferases class-II YP_004161658.1 COGs: COG0505 Carbamoylphosphate synthase small subunit; InterProIPR001317: IPR011702: IPR006220: IPR002474: IPR 000991: IPR006274: IPR017926; KEGG: bth:BT_0556 carbamoyl phosphate synthase small subunit; PFAM: Carbamoyl-phosphate synthase small chain; glutamine amidotransferase class-I; SPTR: uncharacterized protein; TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: Carbamoyl-phosphate synthase small chain, CPSase domain; Glutamine amidotransferase class-I; TIGRFAM: carbamoyl-phosphate synthase, small subunit YP_004161659.1 COGs: COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); InterProIPR005483: IPR005481: IPR005479: IPR005480: IPR 011607: IPR006275: IPR011761; KEGG: bfr:BF2635 carbamyl phosphate synthetase; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; Carbamoyl-phosphate synthetase large chain oligomerisation; MGS domain protein; SPTR: uncharacterized protein; TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain, ATP binding domain; MGS-like domain; Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Carbamoyl-phosphate synthase L chain, N-terminal domain; TIGRFAM: carbamoyl-phosphate synthase, large subunit YP_004161660.1 COGs: COG1538 Outer membrane protein; InterPro IPR003423; KEGG: bvu:BVU_4126 outer membrane protein; PFAM: outer membrane efflux protein; SPTR: uncharacterized protein; PFAM: Outer membrane efflux protein YP_004161661.1 COGs: COG0841 Cation/multidrug efflux pump; InterPro IPR001036; KEGG: bvu:BVU_4125 AcrB/AcrD/AcrF family transporter; PFAM: acriflavin resistance protein; SPTR: uncharacterized protein; PFAM: AcrB/AcrD/AcrF family YP_004161662.1 COGs: COG0845 Membrane-fusion protein; InterPro IPR006143; KEGG: bvu:BVU_4124 lipoprotein; PFAM: hemolysin D; SPTR: uncharacterized protein; TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: HlyD family secretion protein; TIGRFAM: RND family efflux transporter, MFP subunit YP_004161663.1 COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR018060: IPR020449: IPR000005; KEGG: bvu:BVU_4123 transcriptional regulator; PFAM: helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: Transcriptional regulator; PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family YP_004161664.1 KEGG: bfs:BF1890 hypothetical protein; SPTR: uncharacterized protein YP_004161666.1 SPTR: uncharacterized protein YP_004161667.1 InterPro IPR006645; KEGG: bfs:BF0731 transcriptional regulator; PFAM: NGN domain-containing protein; SPTR: transcriptional regulator UpxY homolog; manually curated; PFAM: Transcription termination factor nusG YP_004161668.1 InterPro IPR010570; KEGG: bfs:BF0732 transcriptional regulator; PFAM: protein of unknown function DUF1141; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF1141) YP_004161669.1 InterPro IPR018631; KEGG: pdi:BDI_1343 hypothetical protein; PFAM: AAA-ATPase-like; SPTR: uncharacterized protein; PFAM: Predicted AAA-ATPase YP_004161670.1 InterPro IPR012547; KEGG: bfs:BF2880 hypothetical protein; PFAM: protein of unknown function DUF1703; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF1703) YP_004161671.1 COGs: COG0615 Cytidylyltransferase; InterPro IPR007074: IPR004820: IPR004821; KEGG: pru:PRU_1767 glycerophosphoryl diester phosphodiesterase/cytidylyltransferase; PFAM: cytidylyltransferase; LicD family protein; SPTR: glycerophosphoryl diester phosphodiesterase/cytidylyltransferase; TIGRFAM: cytidyltransferase-related domain protein; PFAM: Cytidylyltransferase; TIGRFAM: glycerol-3-phosphate cytidylyltransferase; cytidyltransferase-related domain YP_004161672.1 COGs: COG0406 Fructose-2 6-bisphosphatase; InterPro IPR013078; KEGG: dsy:DSY1979 alpha-ribazole-5-phosphate phosphatase; PFAM: phosphoglycerate mutase; SPTR: uncharacterized protein; PFAM: phosphoglycerate mutase YP_004161673.1 InterPro IPR007525: IPR017896: IPR017900; KEGG: dps:DPPB80 related to F420H2-dehydrogenase, beta subunit; PFAM: coenzyme F420 hydrogenase/dehydrogenase beta subunit domain protein; SPTR: uncharacterized protein; PFAM: Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus YP_004161674.1 KEGG: esi:Exig_2626 polysaccharide biosynthesis protein; SPTR: EpsT YP_004161675.1 COGs: COG1794 Aspartate racemase; InterPro IPR015942: IPR004380: IPR018187; KEGG: hhe:HH0075 aspartate racemase; PFAM: Asp/Glu/hydantoin racemase; SPTR: Aspartate racemase; TIGRFAM: aspartate racemase; PFAM: Asp/Glu/Hydantoin racemase; TIGRFAM: aspartate racemase YP_004161676.1 COGs: COG1887 glycosyl/glycerophosphate transferase involved in teichoic acid biosynthesis TagF/TagB/EpsJ/RodC; InterPro IPR007577: IPR007554; KEGG: cpe:CPE0482 glycero-phosphotransferase; PFAM: CDP-glycerol:poly(glycerophosphate) glycerophosphotransferase; glycosyltransferase sugar-binding region containing DXD motif; SPTR: CDP-glycerol:poly(glycerophosphate) glycerophosphotransferase; PFAM: glycosyltransferase sugar-binding region containing DXD motif; CDP-glycerol:poly(glycerophosphate) glycerophosphotransferase YP_004161677.1 KEGG: amt:Amet_0211 hypothetical protein; SPTR: uncharacterized protein; PFAM: polysaccharide pyruvyl transferase YP_004161678.1 KEGG: lpl:lp_2101 polysaccharide polymerase; SPTR: polysaccharide polymerase YP_004161679.1 COGs: COG0463 glycosyltransferase involved in cell wall biogenesis; InterPro IPR001173; KEGG: cpe:CPE0501 capsular polysaccharide biosynthsis protein; PFAM: glycosyl transferase 2; SPTR: glycosyl transferase CpsJ; PFAM: glycosyl transferase 2 YP_004161680.1 COGs: COG0463 glycosyltransferase involved in cell wall biogenesis; InterPro IPR001173; KEGG: bpo:BP951000_1254 glycosyltransferase/CDP-glycerol:poly(glycerophosphate) glycerophosphotransferase; PFAM: glycosyl transferase 2; SPTR: glycosyl transferase; PFAM: glycosyl transferase 2 YP_004161681.1 InterPro IPR001173; KEGG: pdi:BDI_1839 glycosyl transferase; PFAM: glycosyl transferase 2; SPTR: glycosyltransferase 2; PFAM: glycosyl transferase 2 YP_004161682.1 KEGG: pti:PHATRDRAFT_42818 hypothetical protein; SPTR: Transposase YP_004161683.1 KEGG: bfo:BRAFLDRAFT_99151 hypothetical protein YP_004161684.1 COGs: COG2148 Sugar transferase involved in lipopolysaccharide synthesis; InterPro IPR003362; KEGG: nis:NIS_1249 UDP-phosphate galactose phosphotransferase; PFAM: sugar transferase; SPTR: uncharacterized protein; PFAM: Bacterial sugar transferase YP_004161685.1 COGs: COG0399 pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; InterPro IPR000653; KEGG: pdi:BDI_3641 aminotransferase; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; SPTR: uncharacterized protein; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase YP_004161686.1 InterPro IPR005902; KEGG: bfr:BF0828 non-specific DNA binding protein; SPTR: uncharacterized protein; TIGRFAM: DNA-binding protein; PFAM: Bacterial DNA-binding protein; TIGRFAM: DNA-binding protein, histone-like YP_004161687.1 KEGG: bfs:BF0755 hypothetical protein; SPTR: uncharacterized protein YP_004161688.1 COGs: COG0556 Helicase subunit of the DNA excision repair complex; InterProIPR014001: IPR001650: IPR006935: IPR001943: IPR 004807: IPR014021; KEGG: bfs:BF2642 excinuclease ABC subunit B; PFAM: helicase domain protein; type III restriction protein res subunit; UvrB/UvrC protein; SMART: DEAD-like helicase; helicase domain protein; SPTR: UvrABC system protein B; TIGRFAM: excinuclease ABC, B subunit; PFAM: Helicase conserved C-terminal domain; UvrB/uvrC motif; type III restriction enzyme, res subunit; Ultra-violet resistance protein B; TIGRFAM: excinuclease ABC, B subunit YP_004161689.1 COGs: COG1541 Coenzyme F390 synthetase; InterPro IPR000873; KEGG: bth:BT_0571 phenylacetate-coenzyme A ligase; PFAM: AMP-dependent synthetase and ligase; PRIAM: Phenylacetate--CoA ligase; SPTR: uncharacterized protein; PFAM: AMP-binding enzyme YP_004161690.1 COGs: COG4747 ACT domain-containing protein; InterPro IPR002912; KEGG: bfs:BF2640 hypothetical protein; PFAM: amino acid-binding ACT domain protein; SPTR: uncharacterized protein YP_004161691.1 COGs: COG4105 DNA uptake lipoprotein; InterPro IPR011716: IPR017689: IPR019734: IPR013026; KEGG: bth:BT_0573 hypothetical protein; PFAM: Tetratricopeptide TPR_3 repeat-containing protein; SPTR: uncharacterized protein; TIGRFAM: outer membrane assembly lipoprotein YfiO; TIGRFAM: outer membrane assembly lipoprotein YfiO YP_004161692.1 KEGG: bth:BT_0574 hypothetical protein; SPTR: uncharacterized protein; PFAM: RNA polymerase Rpb6 YP_004161693.1 KEGG: bfs:BF2637 hypothetical protein; SPTR: uncharacterized protein YP_004161694.1 KEGG: bfs:BF2636 hypothetical protein; SPTR: uncharacterized protein YP_004161695.1 InterPro IPR002482: IPR018392; KEGG: bfs:BF2635 hypothetical protein; PFAM: peptidoglycan-binding lysin domain; SMART: peptidoglycan-binding LysM; SPTR: uncharacterized protein; PFAM: LysM domain YP_004161696.1 COGs: COG0178 excinuclease ATPase subunit; InterPro IPR003593: IPR003439: IPR004602: IPR017871; KEGG: bfs:BF2634 UvrABC SOS-repair system protein excinuclease A; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: uncharacterized protein; TIGRFAM: excinuclease ABC, A subunit; PFAM: ABC transporter; TIGRFAM: excinuclease ABC, A subunit YP_004161697.1 COGs: COG2606 conserved hypothetical protein; InterPro IPR007214: IPR004369; KEGG: bth:BT_0579 transcription regulator; PFAM: YbaK/prolyl-tRNA synthetase associated region; SPTR: YbaK/EbsC family protein; TIGRFAM: ybaK/ebsC protein; PFAM: YbaK / prolyl-tRNA synthetases associated domain; TIGRFAM: ybaK/ebsC protein YP_004161698.1 COGs: COG3104 Dipeptide/tripeptide permease; InterPro IPR000109: IPR005279: IPR018456; KEGG: bth:BT_0580 H+/peptide symporter; PFAM: TGF-beta receptor type I/II extracellular region; SPTR: uncharacterized protein; TIGRFAM: amino acid/peptide transporter; PFAM: POT family; TIGRFAM: amino acid/peptide transporter (peptide:H+ symporter), bacterial YP_004161699.1 InterPro IPR000182; KEGG: bth:BT_0581 GNAT family acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: uncharacterized protein; PFAM: Acetyltransferase (GNAT) family YP_004161700.1 COGs: COG4624 Iron only hydrogenase large subunit C-terminal domain; InterPro IPR004108: IPR017896: IPR017900; KEGG: bvu:BVU_0347 hydrogenase; PFAM: hydrogenase large subunit; SPTR: uncharacterized protein; PFAM: Iron only hydrogenase large subunit, C-terminal domain; 4Fe-4S binding domain YP_004161701.1 COGs: COG0502 Biotin synthase; InterPro IPR006638: IPR007197: IPR005244; KEGG: bvu:BVU_0348 biotin synthase; PFAM: radical SAM protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: uncharacterized protein; PFAM: Radical SAM superfamily YP_004161702.1 COGs: COG1060 Thiamine biosynthesis protein ThiH; InterPro IPR007197: IPR010722; KEGG: bvu:BVU_0349 thiamine biosynthesis protein ThiH; PFAM: biotin and thiamin synthesis associated; radical SAM protein; SPTR: uncharacterized protein; PFAM: Radical SAM superfamily; Biotin and Thiamin Synthesis associated domain; TIGRFAM: thiazole biosynthesis protein ThiH YP_004161703.1 COGs: COG1160 GTPase; InterPro IPR002917: IPR005225; KEGG: bvu:BVU_0350 GTP-binding protein, GTPase; PFAM: GTP-binding protein HSR1-related; SPTR: uncharacterized protein; TIGRFAM: small GTP-binding protein; PFAM: GTPase of unknown function; TIGRFAM: small GTP-binding protein domain YP_004161704.1 COGs: COG1695 transcriptional regulator protein; InterPro IPR005149; KEGG: bth:BT_0582 hypothetical protein; PFAM: transcriptional regulator PadR family protein; SPTR: uncharacterized protein; PFAM: Transcriptional regulator PadR-like family YP_004161705.1 COGs: COG1983 stress-responsive transcriptional regulator protein; InterPro IPR007168; KEGG: bfs:BF2629 hypothetical protein; PFAM: PspC domain protein; SPTR: uncharacterized protein; PFAM: PspC domain YP_004161706.1 InterPro IPR006645; KEGG: bfs:BF1893 LPS biosynthesis related transcriptional regulatory protein; PFAM: NGN domain-containing protein; SPTR: uncharacterized protein; PFAM: Transcription termination factor nusG YP_004161707.1 InterPro IPR010570; KEGG: bfs:BF1894 LPS biosynthesis related transcriptional regulatory protein; PFAM: protein of unknown function DUF1141; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF1141) YP_004161708.1 COGs: COG2089 Sialic acid synthase; InterPro IPR013132; KEGG: pca:Pcar_1277 sialic acid synthase; PFAM: N-acetylneuraminic acid synthase domain; PRIAM: N-acetylneuraminate synthase; SPTR: Sialic acid synthase; PFAM: NeuB family YP_004161709.1 COGs: COG1083 CMP-N-acetylneuraminic acid synthetase; InterPro IPR003329: IPR010023: IPR006549; KEGG: mac:MA3766 acylneuraminate cytidylyltransferase; PFAM: acylneuraminate cytidylyltransferase; SPTR: Acylneuraminate cytidylyltransferase; TIGRFAM: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family; hydrolase, HAD-superfamily, subfamily IIIA; PFAM: Cytidylyltransferase; TIGRFAM: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family; HAD-superfamily hydrolase, subfamily IIIA YP_004161710.1 KEGG: kol:Kole_1286 hypothetical protein; SPTR: Predicted protein YP_004161711.1 COGs: COG2244 Membrane protein involved in the export of O-antigen and teichoic acid; InterPro IPR002797; KEGG: ddf:DEFDS_0379 polysaccharide biosynthesis protein; PFAM: polysaccharide biosynthesis protein; SPTR: Predicted protein; PFAM: polysaccharide biosynthesis protein YP_004161712.1 KEGG: cby:CLM_3076 hypothetical protein; SPTR: CoA-binding domain-containing protein; PFAM: FemAB family YP_004161713.1 COGs: COG0399 pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; KEGG: pmh:P9215_14191 pyridoxal phosphate-dependent enzyme; SPTR: Predicted protein; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase YP_004161714.1 COGs: COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase; InterPro IPR001732: IPR014026: IPR014027: IPR017476; KEGG: pdi:BDI_2219 UDP-glucose-6 dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase; SPTR: uncharacterized protein; TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase, NAD binding domain; UDP-glucose/GDP-mannose dehydrogenase, central domain; UDP-glucose/GDP-mannose dehydrogenase, UDP binding domain; TIGRFAM: nucleotide sugar dehydrogenase YP_004161715.1 COGs: COG0438 glycosyltransferase; InterPro IPR001296; KEGG: dfe:Dfer_4018 glycosyl transferase group 1; PFAM: glycosyl transferase group 1; SPTR: glycosyl transferase group 1; PFAM: glycosyl transferases group 1 YP_004161716.1 KEGG: sde:Sde_2120 hypothetical protein; SPTR: Predicted protein YP_004161717.1 InterPro IPR001173; KEGG: dol:Dole_0525 glycosyl transferase; PFAM: glycosyl transferase 2; SPTR: glycosyl transferase; manually curated; PFAM: glycosyl transferase 2 YP_004161718.1 COGs: COG0463 glycosyltransferase involved in cell wall biogenesis; InterPro IPR001173; KEGG: lba:Lebu_2148 glycosyl transferase 2; PFAM: glycosyl transferase 2; SPTR: uncharacterized protein; PFAM: glycosyl transferase 2 YP_004161719.1 COGs: COG0451 Nucleoside-diphosphate-sugar epimerase; InterPro IPR001509; KEGG: tye:THEYE_A0495 NDP-sugar dehydratase or epimerase, PFAM: NAD-dependent epimerase/dehydratase; SPTR: uncharacterized protein; PFAM: 3-beta hydroxysteroid dehydrogenase/isomerase YP_004161720.1 COGs: COG0463 glycosyltransferase involved in cell wall biogenesis; InterPro IPR001173; KEGG: bfs:BF1024 glycosyltransferase; PFAM: glycosyl transferase 2; SPTR: glycosyltransferase; PFAM: glycosyl transferase 2 YP_004161721.1 COGs: COG1089 GDP-D-mannose dehydratase; InterPro IPR001509: IPR020904: IPR006368; KEGG: bvu:BVU_3946 GDP-mannose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; SPTR: uncharacterized protein; TIGRFAM: GDP-mannose 4,6-dehydratase; PFAM: NAD dependent epimerase/dehydratase; TIGRFAM: GDP-mannose 4,6-dehydratase YP_004161722.1 SPTR: Predicted protein YP_004161723.1 KEGG: sli:Slin_3349 hypothetical protein; SPTR: uncharacterized protein YP_004161724.1 COGs: COG0451 Nucleoside-diphosphate-sugar epimerase; InterPro IPR001509; KEGG: bfs:BF1025 epimerase/dehydratase; PFAM: NAD-dependent epimerase/dehydratase; SPTR: uncharacterized protein; PFAM: NAD dependent epimerase/dehydratase YP_004161725.1 COGs: COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase; InterPro IPR018481; KEGG: bfs:BF1914 LPS biosynthesis related UndPP-QuiNAc-P-transferase; PFAM: glycosyl transferase, family 4, conserved region; SPTR: uncharacterized protein; PFAM: glycosyl transferase 4 YP_004161726.1 COGs: COG0071 Molecular chaperone (small heat shock protein); InterPro IPR002068; KEGG: bfs:BF2646 heat-shock related protein; PFAM: heat shock protein Hsp20; SPTR: uncharacterized protein; PFAM: Hsp20/alpha crystallin family YP_004161727.1 COGs: COG0013 Alanyl-tRNA synthetase; InterPro IPR012947; KEGG: bth:BT_0566 alanyl-tRNA synthetase; PFAM: threonyl/alanyl tRNA synthetase; SPTR: uncharacterized protein; PFAM: Threonyl and Alanyl tRNA synthetase second additional domain YP_004161728.1 COGs: COG1022 Long-chain acyl-CoA synthetase (AMP-forming); InterPro IPR000873: IPR020845; KEGG: bfr:BF2144 long-chain-fatty-acid-CoA ligase; PFAM: AMP-dependent synthetase and ligase; SPTR: uncharacterized protein; PFAM: AMP-binding enzyme YP_004161729.1 COGs: COG3263 NhaP-type Na+/H+ and K+/H+ antiporter with a unique C-terminal domain; InterPro IPR006153: IPR006037; KEGG: bth:BT_0685 potassium/proton antiporter; PFAM: sodium/hydrogen exchanger; TrkA-C domain protein; SPTR: uncharacterized protein; PFAM: Sodium/hydrogen exchanger family; TrkA-C domain; TC 2.A.36 YP_004161730.1 COGs: COG5000 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation; InterPro IPR003594: IPR005467: IPR000014: IPR004358; KEGG: bfr:BF2149 two-component system sensor histidine kinase; PFAM: ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; SPTR: uncharacterized protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase YP_004161731.1 COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterProIPR001789: IPR002078: IPR002197: IPR003593: IPR 020441; KEGG: bth:BT_0690 two-component system response regulator; PFAM: sigma-54 factor interaction domain-containing protein; response regulator receiver; helix-turn-helix Fis-type; SMART: response regulator receiver; AAA ATPase; SPTR: uncharacterized protein; PFAM: Response regulator receiver domain; Bacterial regulatory protein, Fis family; Sigma-54 interaction domain YP_004161732.1 KEGG: bth:BT_0691 hypothetical protein; SPTR: uncharacterized protein YP_004161733.1 InterPro IPR004843; KEGG: bfs:BF2209 lipoprotein; PFAM: metallophosphoesterase; SPTR: uncharacterized protein; PFAM: Calcineurin-like phosphoesterase YP_004161734.1 InterPro IPR003838; KEGG: bth:BT_0693 hypothetical protein; PFAM: protein of unknown function DUF214; SPTR: uncharacterized protein; PFAM: Predicted permease YP_004161735.1 COGs: COG1136 ABC-type antimicrobial peptide transport system ATPase component; InterPro IPR003439: IPR003593: IPR017871; KEGG: bth:BT_0694 ABC transporter, ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: uncharacterized protein; PFAM: ABC transporter; TIGRFAM: bacteriocin export ABC transporter, lactococcin 972 group YP_004161736.1 KEGG: bth:BT_0695 ABC transporter, permease; SPTR: ABC transporter, permease YP_004161737.1 InterPro IPR003838; KEGG: bfr:BF2157 ABC transporter permease; PFAM: protein of unknown function DUF214; SPTR: uncharacterized protein; PFAM: Predicted permease YP_004161738.1 COGs: COG0534 Na+-driven multidrug efflux pump; InterPro IPR002528; KEGG: bth:BT_0696 hypothetical protein; PFAM: multi antimicrobial extrusion protein MatE; SPTR: uncharacterized protein; TIGRFAM: MATE efflux family protein; PFAM: MatE; TIGRFAM: efflux protein, MATE family YP_004161739.1 COGs: COG0637 phosphatase/phosphohexomutase; InterPro IPR005834: IPR006402; KEGG: bth:BT_0697 phosphatase/phosphohexomutase; PFAM: Haloacid dehalogenase domain protein hydrolase; SPTR: uncharacterized protein; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; manually curated; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED YP_004161740.1 COGs: COG0413 Ketopantoate hydroxymethyltransferase; InterPro IPR003700; KEGG: bfs:BF2220 3-methyl-2-oxobutanoate hydroxymethyltransferase; PFAM: Ketopantoate hydroxymethyltransferase; PRIAM: 3-methyl-2-oxobutanoate hydroxymethyltransferase; SPTR: 3-methyl-2-oxobutanoate hydroxymethyltransferase; TIGRFAM: 3-methyl-2-oxobutanoate hydroxymethyltransferase; PFAM: Ketopantoate hydroxymethyltransferase; TIGRFAM: 3-methyl-2-oxobutanoate hydroxymethyltransferase YP_004161741.1 InterPro IPR011701; KEGG: bfr:BF2164 sugar transporter; PFAM: major facilitator superfamily MFS_1; SPTR: uncharacterized protein; PFAM: Major Facilitator Superfamily YP_004161742.1 COGs: COG0818 Diacylglycerol kinase; InterPro IPR000829; KEGG: bfs:BF2222 diacylglycerol kinase; PFAM: diacylglycerol kinase; SPTR: uncharacterized protein; PFAM: Prokaryotic diacylglycerol kinase YP_004161743.1 COGs: COG0317 Guanosine polyphosphate pyrophosphohydrolase/synthetase; InterPro IPR007685: IPR004095: IPR004811; KEGG: bfs:BF2223 GTP pyrophosphokinase; PFAM: RelA/SpoT domain protein; TGS domain-containing protein; PRIAM: GTP diphosphokinase; SPTR: uncharacterized protein; TIGRFAM: RelA/SpoT family protein; PFAM: Region found in RelA / SpoT proteins; TGS domain; TIGRFAM: (p)ppGpp synthetase, RelA/SpoT family YP_004161744.1 COGs: COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)protein; InterPro IPR006665: IPR006690: IPR006664; KEGG: bvu:BVU_2187 hypothetical protein; PFAM: OmpA/MotB domain protein; SPTR: uncharacterized protein; PFAM: OmpA family YP_004161745.1 KEGG: bvu:BVU_2188 hypothetical protein; SPTR: uncharacterized protein YP_004161746.1 InterPro IPR018060; KEGG: bvu:BVU_2189 transcriptional regulator; SMART: Helix-turn-helix, AraC domain; SPTR: Transcriptional regulator YP_004161747.1 KEGG: bfs:BF2224 hypothetical protein; SPTR: uncharacterized protein YP_004161748.1 COGs: COG3525 N-acetyl-beta-hexosaminidase; InterPro IPR015883: IPR001540; KEGG: bfs:BF0669 glycosyl hydrolase, beta-N-acetylhexosaminidase; PFAM: glycoside hydrolase 20; SPTR: Beta-N-acetylhexosaminidase; PFAM: glycosyl hydrolase 20, catalytic domain YP_004161749.1 COGs: COG0027 formate-dependent phosphoribosylglycinamide formyltransferase (GAR transformylase); InterPro IPR003135: IPR005862: IPR011761; KEGG: bth:BT_0704 phosphoribosylglycinamide formyltransferase 2; PFAM: ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; SPTR: phosphoribosylglycinamide formyltransferase 2; PFAM: ATP-grasp domain; TIGRFAM: phosphoribosylglycinamide formyltransferase 2 YP_004161750.1 COGs: COG1947 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase; InterPro IPR006204: IPR013750: IPR004424; KEGG: bfs:BF2610 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; PFAM: GHMP kinase; GHMP kinase domain protein; PRIAM: 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase; SPTR: 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; TIGRFAM: 4-diphosphocytidyl-2C-methyl-D-erythritol kinase; PFAM: GHMP kinases C terminal; GHMP kinases N terminal domain; TIGRFAM: 4-diphosphocytidyl-2C-methyl-D-erythritol kinase YP_004161751.1 COGs: COG0305 Replicative DNA helicase; InterPro IPR007693: IPR007694: IPR007692; KEGG: bth:BT_0625 DNA helicase; PFAM: DnaB domain protein helicase domain protein; SPTR: Replicative DNA helicase; TIGRFAM: replicative DNA helicase; PFAM: DnaB-like helicase N terminal domain; DnaB-like helicase C terminal domain; TIGRFAM: replicative DNA helicase YP_004161752.1 COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR000005: IPR018060: IPR018062: IPR020449; KEGG: pdi:BDI_2989 transcriptional regulator; PFAM: helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: transcriptional regulator; PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family YP_004161753.1 KEGG: bfr:BF2096 hypothetical protein; SPTR: uncharacterized protein YP_004161754.1 COGs: COG0793 Periplasmic protease; InterPro IPR005151; KEGG: bfs:BF2157 lipoprotein; PFAM: peptidase S41; SMART: peptidase S41; SPTR: lipoprotein; PFAM: peptidase S41 YP_004161755.1 InterPro IPR010846; KEGG: bfr:BF2036 xylanase; PFAM: protein of unknown function DUF1460; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF1460) YP_004161756.1 COGs: COG0657 Esterase/lipase; KEGG: bth:BT_1087 xylanase; SPTR: uncharacterized protein; PFAM: alpha/beta hydrolase fold YP_004161757.1 COGs: COG1297 membrane protein; InterPro IPR004813: IPR004814; KEGG: bth:BT_1086 oligopeptide transporter; PFAM: Oligopeptide transporter OPT superfamily protein; SPTR: uncharacterized protein; TIGRFAM: oligopeptide transporter, OPT family; oligopeptide transporters, OPT superfamily; PFAM: OPT oligopeptide transporter protein; TIGRFAM: oligopeptide transporters, OPT superfamily; oligopeptide transporter, OPT family YP_004161758.1 InterPro IPR011467; KEGG: bfs:BF2093 hypothetical protein; PFAM: protein of unknown function DUF1573; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF1573) YP_004161759.1 COGs: COG2243 Precorrin-2 methylase; InterPro IPR000878: IPR003043: IPR012382; KEGG: bfs:BF2245 cobalamin synthesis related methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; SPTR: uncharacterized protein; PFAM: Tetrapyrrole (Corrin/Porphyrin) methylases; TIGRFAM: precorrin-2 C20-methyltransferase YP_004161760.1 COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR018060; KEGG: bvu:BVU_2735 transcriptional regulator; SMART: Helix-turn-helix, AraC domain; SPTR: uncharacterized protein YP_004161761.1 COGs: COG3059 membrane protein; InterPro IPR007339; KEGG: bvu:BVU_2736 hypothetical protein; PFAM: protein of unknown function DUF417; SPTR: uncharacterized protein; PFAM: Protein of unknown function, DUF417 YP_004161762.1 COGs: COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3); InterPro IPR013027: IPR004099: IPR012999: IPR000815; KEGG: bfr:BF1491 pyridine nucleotide-disulfide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; SPTR: uncharacterized protein; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain YP_004161763.1 COGs: COG0614 ABC-type Fe3+-hydroxamate transport system periplasmic component; InterPro IPR002491; KEGG: bfs:BF2246 exported periplasmic protein; PFAM: periplasmic binding protein; SPTR: uncharacterized protein; PFAM: Periplasmic binding protein YP_004161764.1 COGs: COG0609 ABC-type Fe3+-siderophore transport system permease component; InterPro IPR000522; KEGG: bfs:BF2247 iron transport related membrane protein; PFAM: transport system permease; SPTR: uncharacterized protein; PFAM: FecCD transport family YP_004161765.1 COGs: COG1120 ABC-type cobalamin/Fe3+-siderophores transport systems ATPase components; InterPro IPR003439: IPR003593; KEGG: bfr:BF2194 iron(III) ABC transporter ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: uncharacterized protein; PFAM: ABC transporter YP_004161766.1 KEGG: mla:Mlab_1574 hypothetical protein; SPTR: Catalase YP_004161767.1 KEGG: bvu:BVU_1692 hypothetical protein; SPTR: uncharacterized protein YP_004161768.1 COGs: COG1903 Cobalamin biosynthesis protein CbiD; InterPro IPR003723: IPR002748; KEGG: bvu:BVU_3080 precorrin-6x reductase/cobalamin biosynthetic protein CbiD; PFAM: cobalamin (vitamin B12) biosynthesis CbiD protein; Precorrin-6x reductase CbiJ/CobK; SPTR: uncharacterized protein; PFAM: Precorrin-6x reductase CbiJ/CobK; CbiD; TIGRFAM: precorrin-6x reductase; cobalamin biosynthesis protein CbiD YP_004161769.1 COGs: COG2875 Precorrin-4 methylase; InterPro IPR002750: IPR000878: IPR003043: IPR006362; KEGG: bfr:BF2520 precorrin-4 C11-methyltransferase; PFAM: cobalamin (vitamin B12) biosynthesis CbiG protein; Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; PRIAM: Precorrin-4 C(11)-methyltransferase; SPTR: uncharacterized protein; TIGRFAM: precorrin-4 C11-methyltransferase; PFAM: Cobalamin biosynthesis central region; Cobalamin synthesis G C-terminus; Tetrapyrrole (Corrin/Porphyrin) methylases; Cobalamin synthesis G N-terminal; TIGRFAM: precorrin-4 C11-methyltransferase YP_004161770.1 COGs: COG2242 Precorrin-6B methylase 2; InterPro IPR010916: IPR006365: IPR012818: IPR014008; KEGG: bfs:BF2548 bifunctional CbiE/CbiT cobalamin biosynthesis protein; PRIAM: Precorrin-6Y C(5,15)-methyltransferase (decarboxylating); SPTR: uncharacterized protein; TIGRFAM: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; PFAM: Tetrapyrrole (Corrin/Porphyrin) methylases; TIGRFAM: precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit YP_004161771.1 COGs: COG1010 Precorrin-3B methylase; InterPro IPR000878: IPR003722: IPR006363; KEGG: bfr:BF2518 precorrin-3B C17-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Precorrin-8X methylmutase CbiC/CobH; SPTR: uncharacterized protein; TIGRFAM: precorrin-3B C17-methyltransferase; PFAM: Precorrin-8X methylmutase; Tetrapyrrole (Corrin/Porphyrin) methylases; TIGRFAM: precorrin-3B C17-methyltransferase YP_004161772.1 KEGG: cte:CT1927 hypothetical protein; SPTR: uncharacterized protein YP_004161773.1 KEGG: pdi:BDI_0540 hypothetical protein; SPTR: uncharacterized protein; manually curated YP_004161774.1 KEGG: pdi:BDI_1003 hypothetical protein; SPTR: uncharacterized protein; TIGRFAM: DNA-binding protein, histone-like YP_004161775.1 KEGG: bfs:BF2542 hypothetical protein; SPTR: uncharacterized protein YP_004161776.1 COGs: COG4822 Cobalamin biosynthesis protein CbiK Co2+ chelatase; InterPro IPR010388: IPR019758; KEGG: bfr:BF2511 anaerobic cobalt chelatase CbiK; PFAM: anaerobic cobalt chelatase; PRIAM: Sirohydrochlorin cobaltochelatase; SPTR: Anaerobic cobalt chelatase CbiK; PFAM: Cobalt chelatase (CbiK) YP_004161777.1 COGs: COG4771 Outer membrane receptor for ferrienterochelin and colicins; InterPro IPR012910: IPR000531; KEGG: bvu:BVU_3110 iron transport-related exported protein; PFAM: TonB-dependent receptor; TonB-dependent receptor plug; SPTR: uncharacterized protein; PFAM: TonB dependent receptor; TonB-dependent Receptor Plug Domain YP_004161778.1 KEGG: pfh:PFHG_03036 conserved hypothetical protein; SPTR: Zinc finger protein YP_004161779.1 COGs: COG4773 Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid; InterPro IPR012910: IPR000531: IPR010917; KEGG: pdi:BDI_1069 transport-related exported protein; PFAM: TonB-dependent receptor; TonB-dependent receptor plug; SPTR: TonB-dependent outer membrane protein; PFAM: TonB dependent receptor; TonB-dependent Receptor Plug Domain YP_004161780.1 COGs: COG4822 Cobalamin biosynthesis protein CbiK Co2+ chelatase; InterPro IPR010388; KEGG: pru:PRU_1084 cobalt chelatase; PFAM: anaerobic cobalt chelatase; SPTR: Heme-binding protein FetB; PFAM: Cobalt chelatase (CbiK) YP_004161781.1 COGs: COG4771 Outer membrane receptor for ferrienterochelin and colicins; InterPro IPR012910: IPR000531; KEGG: pru:PRU_1085 outer membrane receptor (OMR) family transporter; PFAM: TonB-dependent receptor; TonB-dependent receptor plug; SPTR: TonB-dependent receptor; PFAM: TonB-dependent Receptor Plug Domain; TonB dependent receptor YP_004161782.1 COGs: COG4770 Acetyl/propionyl-CoA carboxylase alpha subunit; InterProIPR005481: IPR005479: IPR005482: IPR011761: IPR 011764: IPR004549; KEGG: bvu:BVU_3104 pyruvate carboxylase subunit A; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; SPTR: Acetyl-CoA carboxylase, biotin carboxylase; TIGRFAM: acetyl-CoA carboxylase, biotin carboxylase; PFAM: Carbamoyl-phosphate synthase L chain, ATP binding domain; Biotin carboxylase C-terminal domain; Carbamoyl-phosphate synthase L chain, N-terminal domain; TIGRFAM: acetyl-CoA carboxylase, biotin carboxylase subunit YP_004161783.1 COGs: COG4770 Acetyl/propionyl-CoA carboxylase alpha subunit; InterPro IPR000089; KEGG: bvu:BVU_3103 hypothetical protein; PFAM: biotin/lipoyl attachment domain-containing protein; SPTR: uncharacterized protein; PFAM: Biotin-requiring enzyme YP_004161784.1 COGs: COG4799 Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta); InterPro IPR000022: IPR011762: IPR011763; KEGG: bvu:BVU_1465 propionyl-CoA carboxylase beta chain; PFAM: carboxyl transferase; SPTR: uncharacterized protein; PFAM: Carboxyl transferase domain YP_004161785.1 COGs: COG2985 permease; InterPro IPR006512: IPR006037: IPR006162; KEGG: bfs:BF2538 hypothetical protein; PFAM: YidE/YbjL duplication domain-containing protein; TrkA-C domain protein; SPTR: uncharacterized protein; TIGRFAM: YidE/YbjL duplication; PFAM: Predicted Permease Membrane Region; TrkA-C domain; TIGRFAM: AspT/YidE/YbjL antiporter duplication domain YP_004161786.1 COGs: COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon); InterPro IPR005835; KEGG: bth:BT_1633 mannose-1-phosphate guanyltransferase; PFAM: Nucleotidyl transferase; SPTR: uncharacterized protein; PFAM: Nucleotidyl transferase YP_004161787.1 COGs: COG1660 P-loop-containing kinase; InterPro IPR002575: IPR005337; KEGG: bth:BT_1634 hypothetical protein; PFAM: aminoglycoside phosphotransferase; SPTR: uncharacterized protein; PFAM: P-loop ATPase; phosphotransferase enzyme family YP_004161788.1 COGs: COG1797 Cobyrinic acid a c-diamide synthase; InterPro IPR011698: IPR017929: IPR004484; KEGG: bfr:BF2503 cobyrinic acid a,c-diamide synthase; PFAM: CobB/CobQ domain protein glutamine amidotransferase; SPTR: uncharacterized protein; TIGRFAM: cobyrinic acid a,c-diamide synthase; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain; CobB/CobQ-like glutamine amidotransferase domain; TIGRFAM: cobyrinic acid a,c-diamide synthase YP_004161789.1 InterPro IPR006645; KEGG: bfs:BF1893 LPS biosynthesis related transcriptional regulatory protein; PFAM: NGN domain-containing protein; SPTR: uncharacterized protein; PFAM: Transcription termination factor nusG YP_004161790.1 InterPro IPR010570; KEGG: bfs:BF2605 transcriptional regulatory protein; PFAM: protein of unknown function DUF1141; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF1141) YP_004161791.1 InterPro IPR002797; KEGG: bvu:BVU_3931 LPS biosynthesis related polysaccharide transporter/flippase; PFAM: polysaccharide biosynthesis protein; SPTR: LPS biosynthesis related polysaccharide transporter/flippase; PFAM: polysaccharide biosynthesis protein YP_004161792.1 InterPro IPR019825; KEGG: ppg:PputGB1_1370 hemolytic protein HlpA-like protein; SPTR: Hemolytic protein HlpA-like protein YP_004161793.1 KEGG: mtp:Mthe_0963 transmembrane protein; SPTR: transmembrane protein YP_004161794.1 COGs: COG0463 glycosyltransferase involved in cell wall biogenesis; InterPro IPR001173; KEGG: eci:UTI89_C2306 rhamnosyltransferase; PFAM: glycosyl transferase 2; SPTR: rhamnosyltransferase; PFAM: glycosyl transferase 2 YP_004161795.1 InterPro IPR001296; KEGG: cce:Ccel_2930 TPR/glycosyl transferase domain-containing protein; PFAM: glycosyl transferase group 1; SPTR: glycosyl transferase group 1; PFAM: glycosyl transferases group 1 YP_004161796.1 COGs: COG0438 glycosyltransferase; InterPro IPR001296; KEGG: bfr:BF3915 glycosyltransferase; PFAM: glycosyl transferase group 1; SPTR: uncharacterized protein; PFAM: glycosyl transferases group 1 YP_004161797.1 COGs: COG1086 nucleoside-diphosphate sugar epimerase; InterPro IPR003869: IPR013692; KEGG: bvu:BVU_1539 dehydratase; PFAM: polysaccharide biosynthesis protein CapD; polysaccharide biosynthesis domain protein; PRIAM: UDP-glucose 4-epimerase; SPTR: uncharacterized protein; PFAM: polysaccharide biosynthesis protein; polysaccharide biosynthesis protein C-terminal YP_004161798.1 KEGG: fsu:Fisuc_0955 hypothetical protein; SPTR: uncharacterized protein YP_004161799.1 InterPro IPR006596: IPR002850; KEGG: bvu:BVU_3921 nucleic acid-binding protein; SMART: Nucleotide binding protein PINc; SPTR: uncharacterized protein; TIGRFAM: probable toxin-antitoxin system toxin component, PIN family YP_004161800.1 COGs: COG0451 Nucleoside-diphosphate-sugar epimerase; InterPro IPR001509; KEGG: bvu:BVU_1540 epimerase/dehydratase; PFAM: NAD-dependent epimerase/dehydratase; SPTR: uncharacterized protein; PFAM: NAD dependent epimerase/dehydratase YP_004161801.1 COGs: COG0381 UDP-N-acetylglucosamine 2-epimerase; InterPro IPR003331; KEGG: bfr:BF1108 epimerase; PFAM: UDP-N-acetylglucosamine 2-epimerase; PRIAM: UDP-N-acetylglucosamine 2-epimerase; SPTR: UDP-N-acetylglucosamine 2-epimerase; TIGRFAM: UDP-N-acetylglucosamine 2-epimerase; PFAM: UDP-N-acetylglucosamine 2-epimerase; TIGRFAM: UDP-N-acetylglucosamine 2-epimerase YP_004161802.1 COGs: COG0438 glycosyltransferase; InterPro IPR001296; KEGG: bfr:BF2568 glycosyltransferase; PFAM: glycosyl transferase group 1; SPTR: glycosyltransferase; PFAM: glycosyl transferases group 1 YP_004161803.1 COGs: COG0451 Nucleoside-diphosphate-sugar epimerase; InterPro IPR001509; KEGG: bfs:BF2592 LPS biosynthesis related DNTP-hexose dehydratase-epimerase; PFAM: NAD-dependent epimerase/dehydratase; SPTR: uncharacterized protein; PFAM: NAD dependent epimerase/dehydratase YP_004161804.1 COGs: COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase; InterPro IPR018481; KEGG: bfr:BF2566 UndPP-QuiNAc-P-transferase; PFAM: glycosyl transferase, family 4, conserved region; SPTR: uncharacterized protein; PFAM: glycosyl transferase 4 YP_004161805.1 COGs: COG2096 conserved hypothetical protein; InterPro IPR002779: IPR017858; KEGG: bfs:BF2533 cobalamin adenosyltransferase; PFAM: cobalamin adenosyltransferase; PRIAM: Cob(I)yrinic acid a,c-diamide adenosyltransferase; SPTR: uncharacterized protein; TIGRFAM: ATP/cobalamin adenosyltransferase; PFAM: Cobalamin adenosyltransferase; TIGRFAM: ATP:cob(I)alamin adenosyltransferase YP_004161806.1 COGs: COG1488 Nicotinic acid phosphoribosyltransferase; InterPro IPR015977: IPR007229: IPR006406; KEGG: bfs:BF3334 nicotinate phosphoribosyltransferase; PFAM: Nicotinate phosphoribosyltransferase-like; PRIAM: Nicotinate phosphoribosyltransferase; SPTR: Nicotinate phosphoribosyltransferase; TIGRFAM: nicotinate phosphoribosyltransferase; PFAM: Nicotinate phosphoribosyltransferase (NAPRTase) family; TIGRFAM: nicotinate phosphoribosyltransferase YP_004161807.1 KEGG: bvu:BVU_1306 hypothetical protein; SPTR: uncharacterized protein YP_004161808.1 KEGG: bvu:BVU_1305 hypothetical protein; SPTR: uncharacterized protein YP_004161809.1 COGs: COG1492 Cobyric acid synthase; InterPro IPR011698: IPR004459: IPR017929; KEGG: bfs:BF2524 cobyric acid synthase; PFAM: CobB/CobQ domain protein glutamine amidotransferase; SPTR: Cobyric acid synthase CobQ; TIGRFAM: cobyric acid synthase CobQ; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain; CobB/CobQ-like glutamine amidotransferase domain; TIGRFAM: cobyric acid synthase CobQ YP_004161810.1 COGs: COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; InterPro IPR004839: IPR004838; KEGG: bfs:BF2523 histidinol-phosphate aminotransferase; PFAM: aminotransferase class I and II; SPTR: uncharacterized protein; PFAM: Aminotransferase class I and II; TIGRFAM: L-threonine-O-3-phosphate decarboxylase YP_004161811.1 COGs: COG1270 Cobalamin biosynthesis protein CobD/CbiB; InterPro IPR004485; KEGG: bfr:BF2489 cobalamin biosynthesis protein CobD; PFAM: cobalamin biosynthesis protein CbiB; SPTR: Cobalamin biosynthesis protein CobD; TIGRFAM: cobalamin biosynthesis protein CobD; PFAM: CobD/Cbib protein; TIGRFAM: cobalamin biosynthesis protein CobD YP_004161812.1 COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661: IPR003594: IPR005467: IPR004358; KEGG: bfr:BF3214 two-component system sensor histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: uncharacterized protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain YP_004161813.1 COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661: IPR005467; KEGG: bth:BT_1598 two-component system sensor histidine kinase; PFAM: histidine kinase A domain protein; SMART: histidine kinase A domain protein; SPTR: uncharacterized protein; PFAM: His Kinase A (phosphoacceptor) domain YP_004161814.1 COGs: COG0406 Fructose-2 6-bisphosphatase; InterPro IPR013078: IPR017578; KEGG: bfr:BF2488 phosphoglycerate mutase; PFAM: phosphoglycerate mutase; SPTR: uncharacterized protein; TIGRFAM: alpha-ribazole phosphatase; PFAM: phosphoglycerate mutase; TIGRFAM: alpha-ribazole phosphatase YP_004161815.1 COGs: COG0368 Cobalamin-5-phosphate synthase; InterPro IPR003805; KEGG: bfr:BF2487 cobalamin 5'-phosphate synthase; PFAM: cobalamin-5-phosphate synthase CobS; SPTR: uncharacterized protein; PFAM: Cobalamin-5-phosphate synthase; TIGRFAM: cobalamin 5'-phosphate synthase/cobalamin synthase YP_004161816.1 COGs: COG2038 NaMN:DMB phosphoribosyltransferase; InterPro IPR003200: IPR017846; KEGG: bfs:BF2519 phosphoribosyltransferase; PFAM: Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase; PRIAM: Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; SPTR: Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; TIGRFAM:nicotinate-nucleotide/dimethylbenzimidazole phosphoribosyltransferase; PFAM: phosphoribosyltransferase; TIGRFAM: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase YP_004161817.1 COGs: COG2087 Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase; InterPro IPR003203; KEGG: bfs:BF2518 bifunctional cobalamin biosynthesis protein; PFAM: cobalbumin biosynthesis protein; PRIAM: Adenosylcobinamide-phosphate guanylyltransferase; SPTR: uncharacterized protein; PFAM: Cobinamide kinase / cobinamide phosphate guanyltransferase YP_004161818.1 COGs: COG0442 Prolyl-tRNA synthetase; InterProIPR002314: IPR004154: IPR016061: IPR004499: IPR 006195; KEGG: bth:BT_0929 prolyl-tRNA synthetase; PFAM: Prolyl-tRNA synthetase, class II-like; Anticodon-binding domain protein; tRNA synthetase class II (G H P and S); PRIAM: Proline--tRNA ligase; SPTR: Prolyl-tRNA synthetase; TIGRFAM: prolyl-tRNA synthetase; PFAM: Anticodon binding domain; Prolyl-tRNA synthetase, C-terminal; tRNA synthetase class II core domain (G, H, P, S and T); TIGRFAM: prolyl-tRNA synthetase, family I YP_004161819.1 KEGG: bfs:BF3012 hypothetical protein; SPTR: uncharacterized protein YP_004161820.1 COGs: COG2908 conserved hypothetical protein; InterPro IPR004843; KEGG: bvu:BVU_2988 phosphoesterase; PFAM: metallophosphoesterase; SPTR: Probable phosphoesterase; PFAM: Calcineurin-like phosphoesterase YP_004161821.1 KEGG: bvu:BVU_2989 glycosyltransferase; SPTR: uncharacterized protein; TIGRFAM: conserved hypothetical protein YP_004161822.1 COGs: COG0855 polyphosphate kinase; InterPro IPR003414; KEGG: bvu:BVU_2990 polyphosphate kinase; PFAM: polyphosphate kinase; PRIAM: polyphosphate kinase; SPTR: polyphosphate kinase; TIGRFAM: polyphosphate kinase; PFAM: polyphosphate kinase; TIGRFAM: polyphosphate kinase 1 YP_004161823.1 COGs: COG0248 Exopolyphosphatase; InterPro IPR003695; KEGG: bvu:BVU_3507 exopolyphosphatase; PFAM: Ppx/GppA phosphatase; SPTR: exopolyphosphatase; PFAM: Ppx/GppA phosphatase YP_004161824.1 InterPro IPR007452; KEGG: bfr:BF2432 hypothetical protein; PFAM: protein of unknown function DUF490; SPTR: uncharacterized protein; PFAM: Family of unknown function (DUF490) YP_004161826.1 COGs: COG0533 Metal-dependent protease with possible chaperone activity; InterPro IPR000905: IPR017860: IPR017861; KEGG: bth:BT_0920 DNA-binding/iron metalloprotein/AP endonuclease; PFAM: peptidase M22 glycoprotease; PRIAM: O-sialoglycoprotein endopeptidase; SPTR: uncharacterized protein; TIGRFAM: metalloendopeptidase, glycoprotease; PFAM: glycoprotease; TIGRFAM: glycoprotease GCP; metallohydrolase, glycoprotease/Kae1 family YP_004161827.1 COGs: COG1546 Uncharacterized protein (competence- and mitomycin-induced); InterPro IPR008136; KEGG: bth:BT_0917 competence-damage inducible protein; PFAM: CinA domain protein; SPTR: uncharacterized protein; PFAM: Competence-damaged protein; TIGRFAM: competence/damage-inducible protein CinA C-terminal domain YP_004161828.1 COGs: COG0227 Ribosomal protein L28; InterPro IPR001383; KEGG: bth:BT_0916 50S ribosomal protein L28; PFAM: ribosomal protein L28; SPTR: 50S ribosomal protein L28; TIGRFAM: ribosomal protein L28; PFAM: Ribosomal L28 family; TIGRFAM: ribosomal protein L28 YP_004161829.1 InterPro IPR001705; KEGG: bfs:BF2509 50S ribosomal protein L33; PFAM: ribosomal protein L33; SPTR: Ribosomal protein L33; TIGRFAM: ribosomal protein L33; PFAM: Ribosomal protein L33; TIGRFAM: ribosomal protein L33, bacterial type YP_004161830.1 KEGG: pru:PRU_0750 hypothetical protein; SPTR: uncharacterized protein YP_004161831.1 COGs: COG0552 Signal recognition particle GTPase; InterPro IPR013822: IPR000897: IPR003593: IPR004390; KEGG: bth:BT_0914 recognition particle-docking protein FtsY; PFAM: GTP-binding signal recognition particle SRP54 G- domain; GTP-binding signal recognition particle SRP54 helical bundle; SMART: AAA ATPase; SPTR: uncharacterized protein; TIGRFAM: signal recognition particle-docking protein FtsY; PFAM: SRP54-type protein, GTPase domain; SRP54-type protein, helical bundle domain; TIGRFAM: signal recognition particle-docking protein FtsY YP_004161832.1 COGs: COG0621 2-methylthioadenine synthetase; InterProIPR013848: IPR007197: IPR005840: IPR006638: IPR 020612: IPR002792: IPR005839; KEGG: bfs:BF2507 oxidoreductase; PFAM: radical SAM protein; protein of unknown function UPF0004; SMART: Elongator protein 3/MiaB/NifB; SPTR: MiaB-like tRNA modifying enzyme YliG; TIGRFAM: MiaB-like tRNA modifying enzyme YliG; RNA modification enzyme, MiaB family; PFAM: Radical SAM superfamily; Uncharacterized protein family UPF0004; TIGRFAM: MiaB-like tRNA modifying enzyme YliG, TIGR01125; RNA modification enzyme, MiaB family YP_004161833.1 COGs: COG0776 Bacterial nucleoid DNA-binding protein; InterPro IPR000119; KEGG: bth:BT_0912 DNA-binding protein HU; PFAM: histone family protein DNA-binding protein; SMART: histone family protein DNA-binding protein; SPTR: uncharacterized protein; PFAM: Bacterial DNA-binding protein YP_004161834.1 COGs: COG0714 MoxR-like ATPase; InterPro IPR011703: IPR016366; KEGG: bfs:BF2504 magnesium chelatase; PFAM: ATPase associated with various cellular activities AAA_3; SPTR: uncharacterized protein; PFAM: ATPase associated with various cellular activities (AAA) YP_004161835.1 COGs: COG1721 conserved hypothetical protein (some members contain a von Willebrand factor A (vWA) domain); InterPro IPR002881; KEGG: bth:BT_0909 hypothetical protein; PFAM: protein of unknown function DUF58; SPTR: uncharacterized protein; PFAM: Protein of unknown function DUF58 YP_004161836.1 KEGG: bfs:BF2502 membrane exported protein; SPTR: uncharacterized protein YP_004161837.1 InterPro IPR002035; KEGG: bth:BT_0907 aerotolerance protein BatA; PFAM: von Willebrand factor A; SMART: von Willebrand factor A; SPTR: uncharacterized protein; PFAM: von Willebrand factor A domain YP_004161838.1 InterPro IPR002035; KEGG: bfr:BF2418 hypothetical protein; PFAM: von Willebrand factor A; SMART: von Willebrand factor A; SPTR: uncharacterized protein; PFAM: von Willebrand factor A domain YP_004161839.1 InterPro IPR001440: IPR019734: IPR013026; KEGG: bfs:BF2499 aerotolerance-related exported protein; PFAM: hypothetical protein; SPTR: uncharacterized protein; PFAM: Tetratricopeptide repeat YP_004161840.1 KEGG: bth:BT_0904 hypothetical protein; SPTR: uncharacterized protein YP_004161841.1 InterPro IPR001440: IPR013247: IPR019734: IPR013026; KEGG: bth:BT_0903 hypothetical protein; PFAM: hypothetical protein; SH3 type 3 domain protein; SMART: Tetratricopeptide repeat; SPTR: uncharacterized protein; PFAM: Tetratricopeptide repeat; Bacterial SH3 domain YP_004161842.1 KEGG: bth:BT_0902 hypothetical protein; SPTR: uncharacterized protein YP_004161843.1 COGs: COG0589 Universal stress protein UspA and related nucleotide-binding protein; InterPro IPR006016: IPR006015; KEGG: bfs:BF2495 hypothetical protein; PFAM: UspA domain-containing protein; SPTR: uncharacterized protein; PFAM: Universal stress protein family YP_004161844.1 InterPro IPR001440: IPR019734: IPR013026; KEGG: bfr:BF2412 TPR repeat-containing protein; PFAM: hypothetical protein; SPTR: uncharacterized protein; PFAM: Tetratricopeptide repeat YP_004161845.1 COGs: COG0188 type IIA topoisomerase (DNA gyrase/topo II topoisomerase IV) A subunit; InterPro IPR002205: IPR006691: IPR005743; KEGG: bfs:BF2493 DNA gyrase A subunit; PFAM: DNA gyrase/topoisomerase IV subunit A; DNA gyrase repeat beta-propeller; PRIAM: DNA topoisomerase (ATP-hydrolyzing); SMART: DNA gyrase/topoisomerase IV subunit A; SPTR: uncharacterized protein; TIGRFAM: DNA gyrase, A subunit; PFAM: DNA gyrase/topoisomerase IV, subunit A; DNA gyrase C-terminal domain, beta-propeller; TIGRFAM: DNA gyrase, A subunit YP_004161846.1 KEGG: pcr:Pcryo_1224 periplasmic sensor signal transduction histidine kinase; SPTR: Periplasmic sensor signal transduction histidine kinase YP_004161847.1 COGs: COG0542 ATPase with chaperone activity ATP-binding subunit; InterProIPR004176: IPR003959: IPR001943: IPR013093: IPR 019489: IPR003593: IPR018368: IPR001270; KEGG: bfs:BF2492 negative regulator of genetic competence; PFAM: ATPase AAA; Clp domain protein; AAA ATPase central domain protein; UvrB/UvrC protein; Clp ATPase-like; SMART: AAA ATPase; SPTR: uncharacterized protein; PFAM: AAA domain (Cdc48 subfamily); C-terminal, D2-small domain, of ClpB protein; Clp amino terminal domain; ATPase associated with various cellular activities (AAA); UvrB/uvrC motif YP_004161848.1 COGs: COG0326 Molecular chaperone HSP90 family; InterProIPR003594: IPR020576: IPR019805: IPR001404: IPR 020575; KEGG: bfs:BF2491 heat shock protein 90; PFAM: ATP-binding region ATPase domain protein; Heat shock protein Hsp90-like; SPTR: uncharacterized protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Hsp90 protein YP_004161849.1 COGs: COG1752 esterase of the alpha-beta hydrolase superfamily; InterPro IPR002641; KEGG: bfs:BF2490 hypothetical protein; PFAM: patatin; SPTR: uncharacterized protein; PFAM: patatin-like phospholipase YP_004161850.1 COGs: COG0329 Dihydrodipicolinate synthase/N-acetylneuraminate lyase; InterPro IPR002220: IPR020625: IPR005479: IPR005263; KEGG: bth:BT_0895 dihydrodipicolinate synthase; PFAM: dihydrodipicolinate synthetase; SPTR: uncharacterized protein; TIGRFAM: dihydrodipicolinate synthase; PFAM: Dihydrodipicolinate synthetase; TIGRFAM: dihydrodipicolinate synthase YP_004161851.1 COGs: COG0272 NAD-dependent DNA ligase (contains BRCT domain type II); InterProIPR013839: IPR004150: IPR004149: IPR001357: IPR 013840: IPR003583: IPR018239: IPR001679; KEGG: bfs:BF2485 DNA ligase; PFAM: NAD-dependent DNA ligase adenylation; NAD-dependent DNA ligase OB-fold; BRCT domain protein; PRIAM: DNA ligase (NAD(+)); SMART: NAD-dependent DNA ligase; Helix-hairpin-helix DNA-binding class 1; BRCT domain protein; SPTR: uncharacterized protein; TIGRFAM: DNA ligase, NAD-dependent; PFAM: NAD-dependent DNA ligase OB-fold domain; NAD-dependent DNA ligase adenylation domain; NAD-dependent DNA ligase C4 zinc finger domain; BRCA1 C Terminus (BRCT) domain; TIGRFAM: DNA ligase, NAD-dependent YP_004161852.1 COGs: COG0336 tRNA-(guanine-N1)-methyltransferase; InterPro IPR016009: IPR002649; KEGG: bth:BT_0893 tRNA (guanine-N(1)-)-methyltransferase; PFAM: tRNA (guanine-N1-)-methyltransferase; PRIAM: tRNA (guanine-N(1)-)-methyltransferase; SPTR: tRNA (guanine-N(1)-)-methyltransferase; TIGRFAM: tRNA (guanine-N1)-methyltransferase; PFAM: tRNA (Guanine-1)-methyltransferase; TIGRFAM: tRNA (guanine-N1)-methyltransferase YP_004161853.1 COGs: COG0167 Dihydroorotate dehydrogenase; InterPro IPR012135: IPR001295: IPR005720; KEGG: bth:BT_0892 dihydroorotate dehydrogenase 1B; PFAM: dihydroorotate oxidase; SPTR: uncharacterized protein; TIGRFAM: dihydroorotate dehydrogenase; PFAM: Dihydroorotate dehydrogenase; TIGRFAM: dihydroorotate dehydrogenase (subfamily 1) family protein YP_004161854.1 COGs: COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductase; InterProIPR008333: IPR001433: IPR019480: IPR012165: IPR 017927: IPR000951; KEGG: bfs:BF2482 dihydroorotate dehydrogenase electron transfer subunit; PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain; SPTR: uncharacterized protein; PFAM: Oxidoreductase FAD-binding domain; Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B; Oxidoreductase NAD-binding domain YP_004161855.1 InterPro IPR010744; KEGG: bth:BT_0890 hypothetical protein; PFAM: CI repressor; SPTR: uncharacterized protein; manually curated; PFAM: Bacteriophage CI repressor helix-turn-helix domain YP_004161856.1 COGs: COG1466 DNA polymerase III delta subunit; InterPro IPR010372: IPR005790; KEGG: bfs:BF2480 hypothetical protein; PFAM: DNA polymerase III delta; SPTR: DNA polymerase III, delta subunit; TIGRFAM: DNA polymerase III, delta subunit; PFAM: DNA polymerase III, delta subunit; TIGRFAM: DNA polymerase III, delta subunit YP_004161857.1 COGs: COG2820 Uridine phosphorylase; InterPro IPR000845: IPR010944; KEGG: bfs:BF2479 AMP nucleosidase; PFAM: purine or other phosphorylase 1; SPTR: AMP nucleosidase; TIGRFAM: AMP nucleosidase; PFAM: phosphorylase superfamily; TIGRFAM: AMP nucleosidase YP_004161858.1 InterPro IPR007409; KEGG: bth:BT_0887 hypothetical protein; PFAM: protein of unknown function DUF450; SPTR: uncharacterized protein YP_004161859.1 InterPro IPR002656; KEGG: pin:Ping_1180 hypothetical protein; PFAM: acyltransferase; SPTR: membrane protein; PFAM: Acyltransferase YP_004161860.1 KEGG: bvu:BVU_0248 hypothetical protein; SPTR: uncharacterized protein YP_004161861.1 KEGG: bvu:BVU_0247 hypothetical protein; SPTR: uncharacterized protein YP_004161862.1 COGs: COG1579 Zn-ribbon protein possibly nucleic acid-binding; InterPro IPR003743; KEGG: bfs:BF2474 hypothetical protein; PFAM: protein of unknown function DUF164; SPTR: uncharacterized protein; PFAM: zinc ribbon domain YP_004161863.1 COGs: COG0327 conserved hypothetical protein; InterPro IPR002678: IPR017221; KEGG: bth:BT_0882 hypothetical protein; PFAM: protein of unknown function DUF34; SPTR: uncharacterized protein; PFAM: NIF3 (NGG1p interacting factor 3); TIGRFAM: dinuclear metal center protein, YbgI/SA1388 family YP_004161864.1 KEGG: bfs:BF2472 hypothetical protein; SPTR: uncharacterized protein YP_004161865.1 COGs: COG0390 ABC-type uncharacterized transport system permease component; InterPro IPR005226; KEGG: bfs:BF2469 ABC transport system, membrane protein; PFAM: Conserved hypothetical protein CHP00245; SPTR: uncharacterized protein; manually curated; PFAM: Uncharacterised protein family (UPF0014); TIGRFAM: conserved hypothetical protein TIGR00245 YP_004161866.1 COGs: COG1136 ABC-type antimicrobial peptide transport system ATPase component; InterPro IPR003439: IPR003593: IPR017871; KEGG: bth:BT_0878 ABC transporter, ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: uncharacterized protein; PFAM: ABC transporter YP_004161867.1 COGs: COG4739 Uncharacterized protein containing a ferredoxin domain; InterPro IPR019224; KEGG: bth:BT_0877 ferredoxin domain-containing protein; PFAM: Protein of unknown function DUF2148; SPTR: uncharacterized protein; PFAM: Uncharacterized protein containing a ferredoxin domain (DUF2148) YP_004161868.1 COGs: COG2957 peptidylarginine deiminase; InterPro IPR007466; KEGG: bth:BT_0876 hypothetical protein; PFAM: Porphyromonas-type peptidyl-arginine deiminase; PRIAM: Agmatine deiminase; SPTR: uncharacterized protein; PFAM: Porphyromonas-type peptidyl-arginine deiminase YP_004161869.1 COGs: COG0388 amidohydrolase; InterPro IPR003010; KEGG: bfs:BF2465 hydrolase; PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; SPTR: uncharacterized protein; PFAM: Carbon-nitrogen hydrolase YP_004161870.1 InterPro IPR007267; KEGG: bfs:BF2464 hypothetical protein; PFAM: GtrA family protein; SPTR: uncharacterized protein; PFAM: GtrA-like protein YP_004161871.1 COGs: COG0173 Aspartyl-tRNA synthetase; InterProIPR004365: IPR004364: IPR004115: IPR006195: IPR 002312: IPR004524; KEGG: bth:BT_0872 aspartyl-tRNA synthetase; PFAM: tRNA synthetase class II (D K and N); nucleic acid binding OB-fold tRNA/helicase-type; GAD domain protein; SPTR: Aspartyl-tRNA synthetase; TIGRFAM: aspartyl-tRNA synthetase; PFAM: GAD domain; tRNA synthetases class II (D, K and N); OB-fold nucleic acid binding domain; TIGRFAM: aspartyl-tRNA synthetase, bacterial type YP_004161872.1 COGs: COG1597 Sphingosine kinase; InterPro IPR001206: IPR005218; KEGG: bfs:BF2462 hypothetical protein; PFAM: diacylglycerol kinase catalytic region; SMART: diacylglycerol kinase catalytic region; SPTR: uncharacterized protein; PFAM: Diacylglycerol kinase catalytic domain; TIGRFAM: lipid kinase, YegS/Rv2252/BmrU family YP_004161873.1 COGs: COG0156 7-keto-8-aminopelargonate synthetase; InterPro IPR004839: IPR001917; KEGG: bvu:BVU_3166 8-amino-7-oxononanoate synthase; PFAM: aminotransferase class I and II; PRIAM: glycine C-acetyltransferase; SPTR: uncharacterized protein; PFAM: Aminotransferase class I and II; TIGRFAM: 8-amino-7-oxononanoate synthase YP_004161874.1 KEGG: dfe:Dfer_2276 alkyl hydroperoxide reductase/thiol specific antioxidant/Mal allergen; SPTR: Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen YP_004161875.1 COGs: COG4123 O-methyltransferase; InterPro IPR007848: IPR002052: IPR002296; KEGG: bth:BT_0838 RNA methyltransferase; PFAM: methyltransferase small; SPTR: uncharacterized protein; PFAM: methyltransferase small domain YP_004161876.1 COGs: COG0466 ATP-dependent Lon protease; InterProIPR003111: IPR003959: IPR003593: IPR008268: IPR 001984: IPR004815; KEGG: bfs:BF2393 ATP-dependent protease; PFAM: peptidase S16 lon domain protein; AAA ATPase central domain protein; PRIAM: Endopeptidase La; SMART: peptidase S16 lon domain protein; AAA ATPase; SPTR: ATP-dependent protease La; TIGRFAM: ATP-dependent protease La; PFAM: ATP-dependent protease La (LON) domain; ATPase associated with various cellular activities (AAA); Lon protease (S16) C-terminal proteolytic domain; TIGRFAM: ATP-dependent protease La YP_004161877.1 COGs: COG0343 Queuine/archaeosine tRNA-ribosyltransferase; InterPro IPR002616: IPR004803; KEGG: bth:BT_0835 tRNA-guanine transglycosylase; PFAM: Queuine/other tRNA-ribosyltransferase; PRIAM: tRNA-guanine transglycosylase; SPTR: uncharacterized protein; TIGRFAM: queuine tRNA-ribosyltransferase; tRNA-guanine transglycosylase, various specificities; PFAM: Queuine tRNA-ribosyltransferase; TIGRFAM: tRNA-guanine transglycosylases, various specificities; tRNA-guanine transglycosylase, queuosine-34-forming YP_004161878.1 COGs: COG0795 permease; InterPro IPR005495; KEGG: bth:BT_0834 hypothetical protein; PFAM: permease YjgP/YjgQ family protein; SPTR: uncharacterized protein; PFAM: Predicted permease YjgP/YjgQ family YP_004161879.1 KEGG: dvi:Dvir_GJ20554 GJ20554 gene product from transcript GJ20554-RA; SPTR: GJ20554 YP_004161880.1 InterPro IPR000866: IPR017936; KEGG: bfs:BF2390 hypothetical protein; PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; SPTR: uncharacterized protein; PFAM: AhpC/TSA family YP_004161882.1 COGs: COG0560 phosphoserine phosphatase; InterPro IPR002912: IPR005834: IPR004469: IPR006383; KEGG: bfs:BF2389 phosphoserine phosphatase; PFAM: Haloacid dehalogenase domain protein hydrolase; amino acid-binding ACT domain protein; PRIAM: phosphoserine phosphatase; SPTR: uncharacterized protein; TIGRFAM: phosphoserine phosphatase SerB; HAD-superfamily hydrolase, subfamily IB (PSPase-like); PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: Haloacid Dehalogenase superfamily, subfamily IB, phosphoserine phosphatase-like; phosphoserine phosphatase SerB YP_004161883.1 COGs: COG0513 Superfamily II DNA and RNA helicase; InterProIPR011545: IPR001650: IPR014001: IPR000629: IPR 014021: IPR014014; KEGG: bfs:BF2388 ATP-dependent RNA helicase; PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; SPTR: uncharacterized protein; PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase YP_004161884.1 KEGG: bfr:BF2298 hypothetical protein; SPTR: uncharacterized protein YP_004161885.1 COGs: COG1004 UDP-glucose 6-dehydrogenase; InterPro IPR001732: IPR014026: IPR014027: IPR017476; KEGG: bfr:BF2297 UDP-glucose 6-dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase; PRIAM: UDP-glucose 6-dehydrogenase; SPTR: uncharacterized protein; TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase, NAD binding domain; UDP-glucose/GDP-mannose dehydrogenase, central domain; UDP-glucose/GDP-mannose dehydrogenase, UDP binding domain; TIGRFAM: nucleotide sugar dehydrogenase YP_004161886.1 COGs: COG1898 dTDP-4-dehydrorhamnose 3 5-epimerase; InterPro IPR000888; KEGG: bth:BT_0828 dTDP-4-dehydrorhamnose 3,5-epimerase; PFAM: dTDP-4-dehydrorhamnose 35-epimerase related; PRIAM: dTDP-4-dehydrorhamnose 3,5-epimerase; SPTR: uncharacterized protein; TIGRFAM: dTDP-4-dehydrorhamnose 3,5-epimerase; PFAM: dTDP-4-dehydrorhamnose 3,5-epimerase; TIGRFAM: dTDP-4-dehydrorhamnose 3,5-epimerase YP_004161887.1 InterPro IPR007730; KEGG: bfs:BF2384 hypothetical protein; PFAM: Sporulation domain-containing protein; SPTR: uncharacterized protein; PFAM: Sporulation related domain YP_004161888.1 InterPro IPR000253; KEGG: bfs:BF2383 hypothetical protein; PFAM: Forkhead-associated protein; SPTR: uncharacterized protein; PFAM: FHA domain YP_004161890.1 COGs: COG1904 glucuronate isomerase; InterPro IPR003766; KEGG: bth:BT_0823 glucuronate isomerase; PFAM: glucuronate isomerase; PRIAM: glucuronate isomerase; SPTR: Uronate isomerase; PFAM: glucuronate isomerase YP_004161891.1 COGs: COG1235 Metal-dependent hydrolase of the beta-lactamase superfamily I; KEGG: bth:BT_0822 metallo-beta-lactamase superfamily hydrolase; SPTR: uncharacterized protein; PFAM: Metallo-beta-lactamase superfamily YP_004161892.1 InterPro IPR015067; KEGG: bfr:BF4297 TonB-dependent outer membrane receptor; PFAM: Domain of unknown function DUF1893; SPTR: uncharacterized protein; PFAM: Domain of unknown function (DUF1893) YP_004161893.1 COGs: COG2194 membrane-associated metal-dependent hydrolase; InterPro IPR000917; KEGG: bth:BT_1813 integral membrane protein; PFAM: sulfatase; SPTR: uncharacterized protein; manually curated; PFAM: Sulfatase; Domain of unknown function (DUF1705) YP_004161894.1 InterPro IPR000184; KEGG: bth:BT_1814 hypothetical protein; PFAM: surface antigen (D15); SPTR: uncharacterized protein; PFAM: Surface antigen YP_004161895.1 InterPro IPR011637; KEGG: bfr:BF2284 hypothetical protein; PFAM: DoxX family protein; SPTR: uncharacterized protein; PFAM: DoxX YP_004161896.1 KEGG: bfs:BF2375 hypothetical protein; SPTR: uncharacterized protein; PFAM: Domain of unknown function (DUF3332) YP_004161897.1 COGs: COG4775 Outer membrane protein/protective antigen OMA87; InterPro IPR000184: IPR005829; KEGG: bfr:BF2282 outer membrane protein; PFAM: surface antigen (D15); SPTR: uncharacterized protein; PFAM: Surface antigen YP_004161898.1 COGs: COG0566 rRNA methylase; InterPro IPR001537; KEGG: bth:BT_0811 tRNA/rRNA methyltransferase; PFAM: tRNA/rRNA methyltransferase (SpoU); SPTR: uncharacterized protein; PFAM: SpoU rRNA methylase YP_004161899.1 KEGG: bth:BT_0810 hypothetical protein; SPTR: uncharacterized protein YP_004161900.1 KEGG: bfr:BF2278 hypothetical protein; SPTR: uncharacterized protein YP_004161901.1 COGs: COG0597 Lipoprotein signal peptidase; InterPro IPR001872; KEGG: bfs:BF2369 lipoprotein signal peptidase; PFAM: peptidase A8 signal peptidase II; SPTR: uncharacterized protein; PFAM: Signal peptidase (SPase) II YP_004161902.1 InterPro IPR000962; KEGG: bth:BT_0807 DnaK suppressor protein, SPTR: uncharacterized protein; PFAM: Prokaryotic dksA/traR C4-type zinc finger; TIGRFAM: RNA polymerase-binding protein DksA YP_004161903.1 COGs: COG0060 isoleucyl-tRNA synthetase; InterPro IPR002300: IPR013155: IPR015905: IPR002301; KEGG: bth:BT_0806 isoleucyl-tRNA synthetase; PFAM: aminoacyl-tRNA synthetase class Ia; tRNA synthetase valyl/leucyl anticodon-binding; SPTR: uncharacterized protein; TIGRFAM: isoleucyl-tRNA synthetase; PFAM: tRNA synthetases class I (I, L, M and V); Anticodon-binding domain; TIGRFAM: isoleucyl-tRNA synthetase YP_004161904.1 COGs: COG0388 amidohydrolase; InterPro IPR000182: IPR003010: IPR001110; KEGG: bfs:BF2359 carbon-nitrogen hydrolase; PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; GCN5-related N-acetyltransferase; SPTR: uncharacterized protein; PFAM: Acetyltransferase (GNAT) family; Carbon-nitrogen hydrolase YP_004161905.1 InterPro IPR005144: IPR013509: IPR000788: IPR013346; KEGG: bfs:BF2713 ribonucleotide-diphosphate reductase subunit alpha; PFAM: ribonucleotide reductase large subunit; Ribonucleotide reductase large subunit domain protein; ATP-cone domain protein; SPTR: Ribonucleoside-diphosphate reductase; TIGRFAM: ribonucleoside-diphosphate reductase, alpha subunit; PFAM: Ribonucleotide reductase, all-alpha domain; ATP cone domain; Ribonucleotide reductase, barrel domain; TIGRFAM: ribonucleoside-diphosphate reductase, alpha subunit YP_004161906.1 COGs: COG0208 Ribonucleotide reductase beta subunit; InterPro IPR000358; KEGG: bvu:BVU_3097 ribonucleotide-diphosphate reductase subunit beta; PFAM: ribonucleotide reductase; SPTR: Ribonucleotide-diphosphate reductase subunit beta; PFAM: Ribonucleotide reductase, small chain YP_004161907.1 COGs: COG1524 Uncharacterized protein of the AP superfamily; InterPro IPR002591; KEGG: bfs:BF2358 phosphodiesterase-nucleotide pyrophosphatase; PFAM: type I phosphodiesterase/nucleotide pyrophosphatase; PRIAM: Sphingomyelin phosphodiesterase; SPTR: uncharacterized protein; PFAM: type I phosphodiesterase / nucleotide pyrophosphatase YP_004161908.1 InterPro IPR005829: IPR003663; KEGG: pru:PRU_1620 D-xylose:proton symporter; SPTR: uncharacterized protein; TIGRFAM: sugar transporter; PFAM: Sugar (and other) transporter; TIGRFAM: MFS transporter, sugar porter (SP) family YP_004161909.1 COGs: COG2115 Xylose isomerase; InterPro IPR012307: IPR001998: IPR013452; KEGG: bvu:BVU_3953 xylose isomerase; PFAM: Xylose isomerase domain-containing protein TIM barrel; PRIAM: Xylose isomerase; SPTR: Xylose isomerase; TIGRFAM: xylose isomerase; PFAM: Xylose isomerase-like TIM barrel; TIGRFAM: xylose isomerase YP_004161910.1 COGs: COG1070 Sugar (pentulose and hexulose) kinase; InterPro IPR018484: IPR018485; KEGG: bth:BT_0792 xylulose kinase (xylulokinase); PFAM: Carbohydrate kinase, FGGY-like; SPTR: uncharacterized protein; PFAM: FGGY family of carbohydrate kinases, N-terminal domain; FGGY family of carbohydrate kinases, C-terminal domain YP_004161911.1 InterPro IPR000086; KEGG: bth:BT_0791 hypothetical protein; PFAM: NUDIX hydrolase; SPTR: uncharacterized protein; PFAM: NUDIX domain YP_004161912.1 COGs: COG0331 ACP S-malonyltransferase; InterPro IPR014043: IPR016160: IPR004410; KEGG: bth:BT_0789 malonyl CoA-ACP transacylase; PFAM: Acyl transferase; SPTR: Malonyl CoA-ACP transacylase; TIGRFAM: malonyl CoA-ACP transacylase; PFAM: Acyl transferase domain; TIGRFAM: malonyl CoA-ACP transacylase YP_004161914.1 InterPro IPR003749: IPR010035; KEGG: bfr:BF2528 ThiS protein involved in thiamine biosynthesis; PFAM: thiamineS protein; SPTR: uncharacterized protein; TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: ThiS family; TIGRFAM: thiamine biosynthesis protein ThiS YP_004161915.1 COGs: COG0352 Thiamine monophosphate synthase; InterPro IPR003733; KEGG: bvu:BVU_3541 thiamine-phosphate pyrophosphorylase; PFAM: thiamine monophosphate synthase; SPTR: Thiamine-phosphate pyrophosphorylase; TIGRFAM: thiamine-phosphate pyrophosphorylase; PFAM: Thiamine monophosphate synthase/TENI; TIGRFAM: thiamine-phosphate pyrophosphorylase YP_004161916.1 COGs: COG2022 Uncharacterized protein of thiazole biosynthesis; InterPro IPR008867; KEGG: bfs:BF2559 thiazole synthase; PFAM: thiazole biosynthesis family protein; SPTR: Thiazole synthase; PFAM: Thiazole biosynthesis protein ThiG YP_004161917.1 COGs: COG0422 Thiamine biosynthesis protein ThiC; InterPro IPR002817; KEGG: bfs:BF2560 thiamine biosynthesis protein ThiC; PFAM: thiamine biosynthesis protein ThiC; SPTR: phosphomethylpyrimidine synthase; TIGRFAM: thiamine biosynthesis protein ThiC; PFAM: ThiC family; TIGRFAM: thiamine biosynthesis protein ThiC YP_004161918.1 COGs: COG1060 Thiamine biosynthesis protein ThiH; InterPro IPR007197: IPR010722: IPR012726; KEGG: bth:BT_0649 thiamine biosynthesis protein ThiH; PFAM: biotin and thiamin synthesis associated; radical SAM protein; SPTR: uncharacterized protein; TIGRFAM: thiazole biosynthesis protein ThiH; PFAM: Biotin and Thiamin Synthesis associated domain; TIGRFAM: thiazole biosynthesis protein ThiH YP_004161919.1 COGs: COG0476 Dinucleotide-utilizing protein involved in molybdopterin and thiamine biosynthesis family 2; InterPro IPR000594: IPR007901; KEGG: bfs:BF2563 molybdopterin biosynthesis-related protein; PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; SPTR: uncharacterized protein; PFAM: MoeZ/MoeB domain; ThiF family YP_004161920.1 COGs: COG0352 Thiamine monophosphate synthase; InterPro IPR003733; KEGG: bvu:BVU_3550 thiamine phosphate pyrophosphorylase; PFAM: thiamine monophosphate synthase; SPTR: uncharacterized protein; PFAM: Thiamine monophosphate synthase/TENI YP_004161921.1 COGs: COG0351 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase; InterPro IPR013749: IPR004399; KEGG: bth:BT_0790 phosphomethylpyrimidine kinase; PFAM: phosphomethylpyrimidine kinase type-1; PRIAM: phosphomethylpyrimidine kinase; SPTR: uncharacterized protein; TIGRFAM: phosphomethylpyrimidine kinase; PFAM: phosphomethylpyrimidine kinase; TIGRFAM: phosphomethylpyrimidine kinase YP_004161922.1 COGs: COG1752 esterase of the alpha-beta hydrolase superfamily; InterPro IPR002641; KEGG: bth:BT_0774 hypothetical protein; PFAM: patatin; SPTR: uncharacterized protein; PFAM: patatin-like phospholipase YP_004161923.1 COGs: COG0366 glycosidase; InterPro IPR006047: IPR006589; KEGG: bfs:BF2339 amylase; PFAM: alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; SPTR: uncharacterized protein; PFAM: Alpha amylase, catalytic domain YP_004161924.1 KEGG: bfs:BF1922 hypothetical protein; SPTR: uncharacterized protein YP_004161925.1 COGs: COG5587 conserved hypothetical protein; InterPro IPR012808: IPR015996; KEGG: bfs:BF2337 hypothetical protein; PFAM: Conserved hypothetical protein CHP02453; SPTR: uncharacterized protein; PFAM: Conserved hypothetical protein (DUF2461); TIGRFAM: conserved hypothetical protein TIGR02453 YP_004161926.1 COGs: COG2731 Beta-galactosidase beta subunit; InterPro IPR004375; KEGG: bth:BT_0770 hypothetical protein; PFAM: Conserved hypothetical protein CHP00022; SPTR: Uncharacterized protein, YhcH/YjgK/YiaL family; PFAM: Domain of unknown function (DUF386); TIGRFAM: uncharacterized protein, YhcH/YjgK/YiaL family YP_004161927.1 COGs: COG0296 1 4-alpha-glucan branching enzyme; InterPro IPR004193: IPR006047: IPR006048: IPR006589; KEGG: bfr:BF2243 1,4-alpha-glucan branching enzyme; PFAM: alpha amylase all-beta; glycoside hydrolase 13 domain protein; alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; SPTR: uncharacterized protein; PFAM: Alpha amylase, C-terminal all-beta domain; Carbohydrate-binding module 48 (Isoamylase N-terminal domain); Alpha amylase, catalytic domain YP_004161928.1 InterPro IPR001440: IPR019734: IPR013026; KEGG: bfs:BF2334 hypothetical protein; PFAM: hypothetical protein; SPTR: uncharacterized protein YP_004161929.1 InterPro IPR019620; KEGG: pdi:BDI_1027 hypothetical protein; PFAM: Protein of unknown function DUF2492; SPTR: uncharacterized protein; TIGRFAM: Protein of unknown function DUF2492; PFAM: Protein of unknown function (DUF2492); TIGRFAM: probable metal-binding protein YP_004161930.1 KEGG: fps:FP2425 lipoprotein precursor; SPTR: Predicted protein YP_004161931.1 KEGG: bfs:BF1639 hypothetical protein; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF2874) YP_004161932.1 COGs: COG4413 Urea transporter; InterPro IPR004937; KEGG: bfs:BF1925 UreA transport protein; PFAM: Urea transporter; SPTR: urea transport protein; PFAM: Urea transporter; TIGRFAM: urea transporter, Yersinia type YP_004161933.1 KEGG: cim:CIMG_09847 hypothetical protein YP_004161934.1 COGs: COG3015 Uncharacterized lipoprotein NlpE involved in copper resistance; KEGG: amu:Amuc_1432 lipoprotein; SPTR: Conserved domain protein; PFAM: Uncharacterized lipoprotein NlpE involved in copper resistance YP_004161935.1 KEGG: bvu:BVU_3699 hypothetical protein; SPTR: uncharacterized protein YP_004161936.1 COGs: COG1629 Outer membrane receptor protein mostly Fe transport; InterPro IPR012910: IPR000531; KEGG: bvu:BVU_3700 outer membrane protein; PFAM: TonB-dependent receptor; TonB-dependent receptor plug; SPTR: TonB-dependent receptor; PFAM: TonB-dependent Receptor Plug Domain YP_004161937.1 KEGG: bvu:BVU_3701 hypothetical protein; SPTR: uncharacterized protein; manually curated YP_004161938.1 KEGG: bfs:BF0577 lipoprotein; SPTR: uncharacterized protein YP_004161939.1 COGs: COG1629 Outer membrane receptor protein mostly Fe transport; InterPro IPR012910: IPR000531; KEGG: bfr:BF0628 TonB-linked outer membrane receptor; PFAM: TonB-dependent receptor plug; TonB-dependent receptor; SPTR: TonB-dependent receptor plug domain protein; PFAM: TonB-dependent Receptor Plug Domain; PEGA domain YP_004161940.1 SPTR: Predicted protein YP_004161941.1 KEGG: bvu:BVU_2848 hypothetical protein; SPTR: NUMOD4 motif superfamily YP_004161942.1 COGs: COG0358 DNA primase; InterPro IPR002694; KEGG: bfs:BF2325 DNA primase; SPTR: uncharacterized protein; PFAM: CHC2 zinc finger; TIGRFAM: DNA primase, catalytic core YP_004161943.1 KEGG: bfs:BF2323 hypothetical protein; SPTR: uncharacterized protein YP_004161944.1 KEGG: bfs:BF2322 hypothetical protein; SPTR: uncharacterized protein YP_004161945.1 KEGG: dvi:Dvir_GJ14029 GJ14029 gene product from transcript GJ14029-RA; SPTR: GJ14029 YP_004161946.1 KEGG: ttu:TERTU_2884 transmembrane sensor; SPTR: uncharacterized protein YP_004161947.1 KEGG: tps:THAPSDRAFT_22180 hypothetical protein; SPTR: uncharacterized protein YP_004161948.1 COGs: COG0740 Protease subunit of ATP-dependent Clp protease; InterPro IPR001907; KEGG: pru:PRU_0953 Clp protease; PFAM: peptidase S14 ClpP; SPTR: uncharacterized protein; PFAM: Clp protease YP_004161949.1 KEGG: pru:PRU_0952 hypothetical protein; SPTR: uncharacterized protein YP_004161950.1 KEGG: bfs:BF2317 hypothetical protein; SPTR: uncharacterized protein YP_004161951.1 KEGG: aga:AgaP_AGAP008674 AGAP008674-PA; SPTR: uncharacterized protein YP_004161952.1 KEGG: plm:Plim_2133 hypothetical protein; SPTR: uncharacterized protein YP_004161953.1 KEGG: ptm:GSPATT00035844001 hypothetical protein; SPTR: uncharacterized protein YP_004161954.1 SPTR: uncharacterized protein YP_004161955.1 KEGG: pru:PRU_0944 hypothetical protein; SPTR: uncharacterized protein YP_004161956.1 KEGG: smf:Smon_0055 hypothetical protein; SPTR: uncharacterized protein YP_004161957.1 KEGG: bfs:BF2310 hypothetical protein; SPTR: uncharacterized protein; PFAM: Domain of unknown function (DUF1738) YP_004161958.1 KEGG: tva:TVAG_248740 hypothetical protein; SPTR: uncharacterized protein YP_004161959.1 COGs: COG2003 DNA repair protein; InterPro IPR001405: IPR020891; KEGG: bfr:BF0483 DNA repair protein; PFAM: DNA repair protein RadC; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF2466); TIGRFAM: DNA repair protein radc YP_004161960.1 KEGG: ljo:LJ0700 glycerol uptake facilitator protein; SPTR: uncharacterized protein; PFAM: Holin family YP_004161961.1 KEGG: mac:MA1355 aldehyde dehydrogenase; SPTR: uncharacterized protein YP_004161962.1 KEGG: clj:CLJU_c13030 elongation factor Ts; SPTR: uncharacterized protein YP_004161963.1 KEGG: bhy:BHWA1_01579 penicillin binding protein; SPTR: uncharacterized protein YP_004161964.1 KEGG: bfs:BF2306 hypothetical protein; SPTR: uncharacterized protein YP_004161965.1 KEGG: bfs:BF2305 hypothetical protein; SPTR: uncharacterized protein YP_004161966.1 KEGG: pfd:PFDG_03850 predicted protein; SPTR: uncharacterized protein YP_004161967.1 KEGG: dpe:Dper_GL15116 GL15116 gene product from transcript GL15116-RA; SPTR: uncharacterized protein YP_004161968.1 InterPro IPR006089; KEGG: pmr:PMI0527 phage host specificity protein; SPTR: Predicted protein YP_004161969.1 KEGG: aga:AgaP_AGAP002830 AGAP002830-PA; SPTR: uncharacterized protein YP_004161970.1 KEGG: ppp:PHYPADRAFT_198113 hypothetical protein YP_004161971.1 COGs: COG3926 secretion activating protein; InterPro IPR008565: IPR018537; KEGG: pgn:PGN_1670 conserved hypothetical protein with predicted lysozyme domain; PFAM: protein of unknown function DUF847; peptidoglycan binding domain; SPTR: uncharacterized protein; PFAM: Predicted peptidoglycan domain; Predicted lysozyme (DUF847) YP_004161972.1 KEGG: bfs:BF2295 hypothetical protein; SPTR: uncharacterized protein YP_004161973.1 InterPro IPR010090; KEGG: bfs:BF2294 hypothetical protein; PFAM: tail tape measure protein TP901 core region; SPTR: uncharacterized protein; TIGRFAM: phage tail tape measure protein, TP901 family; PFAM: Phage-related minor tail protein; TIGRFAM: phage tail tape measure protein, TP901 family, core region YP_004161974.1 KEGG: pru:PRU_0912 hypothetical protein; SPTR: uncharacterized protein YP_004161975.1 SPTR: ArsR-family transcription regulator YP_004161976.1 KEGG: bth:BT_4467 hypothetical protein; SPTR: uncharacterized protein YP_004161977.1 KEGG: bfr:BF1566 hypothetical protein; SPTR: uncharacterized protein; PFAM: MAC/Perforin domain YP_004161978.1 InterPro IPR020864; KEGG: bfr:BF1566 hypothetical protein; PFAM: Membrane attack complex component/perforin (MACPF) domain; SPTR: uncharacterized protein; manually curated; PFAM: MAC/Perforin domain YP_004161979.1 KEGG: bfs:BF2302 hypothetical protein; SPTR: uncharacterized protein YP_004161980.1 KEGG: hje:HacjB3_10965 phenylalanyl-tRNA synthetase subunit alpha; SPTR: Predicted protein YP_004161981.1 KEGG: dwi:Dwil_GK14371 GK14371 gene product from transcript GK14371-RA; SPTR: GK14371 YP_004161982.1 KEGG: tet:TTHERM_00219480 hypothetical protein; SPTR: von Willebrand factor A domain protein YP_004161984.1 KEGG: bfs:BF2297 hypothetical protein; SPTR: uncharacterized protein YP_004161985.1 KEGG: cph:Cpha266_2319 FG-GAP repeat-containing protein; SPTR: uncharacterized protein YP_004161986.1 KEGG: tet:TTHERM_01060850 hypothetical protein; SPTR: uncharacterized protein YP_004161987.1 COGs: COG4974 Site-specific recombinase XerD; InterPro IPR002104; KEGG: bfs:BF2284 phage integrase; PFAM: integrase; SPTR: uncharacterized protein; PFAM: Phage integrase YP_004161988.1 COGs: COG2978 p-aminobenzoyl-glutamate transporter; InterPro IPR004697; KEGG: bfs:BF2283 transport-related membrane protein; PFAM: AbgT transporter; SPTR: uncharacterized protein; PFAM: AbgT transporter family; TIGRFAM: p-Aminobenzoyl-glutamate transporter family YP_004161989.1 COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR001789; KEGG: bfs:BF2282 two component system response regulator; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: uncharacterized protein; PFAM: Response regulator receiver domain YP_004161990.1 COGs: COG0642 Signal transduction histidine kinase; InterProIPR001440: IPR003594: IPR019734: IPR005467: IPR 013026; KEGG: bfs:BF2281 two component system sensor histidine kinase; PFAM: ATP-binding region ATPase domain protein; hypothetical protein; SMART: ATP-binding region ATPase domain protein; Tetratricopeptide repeat; SPTR: uncharacterized protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase YP_004161991.1 COGs: COG0462 phosphoribosylpyrophosphate synthetase; InterPro IPR000836: IPR000842: IPR005946; KEGG: bth:BT_0748 ribose-phosphate pyrophosphokinase; PFAM: phosphoribosyltransferase; PRIAM: Ribose-phosphate diphosphokinase; SPTR: Ribose-phosphate pyrophosphokinase; TIGRFAM: ribose-phosphate pyrophosphokinase; PFAM: phosphoribosyl transferase domain; TIGRFAM: ribose-phosphate pyrophosphokinase YP_004161992.1 COGs: COG4642 conserved hypothetical protein; InterPro IPR003409; KEGG: bfs:BF2279 hypothetical protein; PFAM: MORN repeat-containing protein; SPTR: uncharacterized protein; PFAM: MORN repeat YP_004161993.1 COGs: COG0612 Zn-dependent peptidase; InterPro IPR007863; KEGG: bfr:BF2229 zinc protease; PFAM: peptidase M16; SPTR: uncharacterized protein; PFAM: peptidase M16 inactive domain; Insulinase (peptidase M16) YP_004161994.1 COGs: COG1212 CMP-2-keto-3-deoxyoctulosonic acid synthetase; InterPro IPR003329: IPR004528; KEGG: bth:BT_0745 3-deoxy-manno-octulosonate cytidylyltransferase; PFAM: acylneuraminate cytidylyltransferase; PRIAM: 3-deoxy-manno-octulosonate cytidylyltransferase; SPTR: 3-deoxy-D-manno-octulosonate cytidylyltransferase; TIGRFAM: 3-deoxy-D-manno-octulosonate cytidylyltransferase; PFAM: Cytidylyltransferase; TIGRFAM: 3-deoxy-D-manno-octulosonate cytidylyltransferase YP_004161995.1 KEGG: bth:BT_0744 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; SPTR: uncharacterized protein; PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK); TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase YP_004161996.1 COGs: COG5009 Membrane carboxypeptidase/penicillin-binding protein; InterPro IPR001264: IPR001460; KEGG: bfs:BF2276 penicillin-binding peptidoglycan biosynthesis-related exported protein; PFAM: glycosyl transferase 51; penicillin-binding protein transpeptidase; PRIAM: peptidoglycan glycosyltransferase; SPTR: uncharacterized protein; PFAM: Penicillin binding protein transpeptidase domain; Transglycosylase YP_004161997.1 COGs: COG0399 pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; InterPro IPR000653; KEGG: pdi:BDI_3641 aminotransferase; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; SPTR: uncharacterized protein; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase YP_004161998.1 COGs: COG0663 Carbonic anhydrase/acetyltransferase isoleucine patch superfamily; InterPro IPR001451: IPR018357: IPR020019; KEGG: bfs:BF0750 acetyltransferase; SPTR: uncharacterized protein; TIGRFAM: sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family; TIGRFAM: sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family YP_004161999.1 COGs: COG2148 Sugar transferase involved in lipopolysaccharide synthesis; InterPro IPR003362; KEGG: bfr:BF1110 UDP-phosphate glycosyl-1-phosphate transferase; PFAM: sugar transferase; PRIAM: UDP-phosphate galactose phosphotransferase; SPTR: uncharacterized protein; PFAM: Bacterial sugar transferase YP_004162000.1 COGs: COG0438 glycosyltransferase; InterPro IPR001296; KEGG: bfs:BF0748 glycosyltransferase; PFAM: glycosyl transferase group 1; SPTR: glycosyltransferase; PFAM: glycosyl transferases group 1 YP_004162001.1 InterPro IPR012480; KEGG: bfs:BF0747 hypothetical protein; PFAM: Heparinase II/III family protein; SPTR: uncharacterized protein; PFAM: Heparinase II/III-like protein YP_004162002.1 COGs: COG0673 dehydrogenase and related protein; InterPro IPR013154: IPR013149: IPR000683; KEGG: pdi:BDI_1580 zinc-binding dehydrogenase; PFAM: oxidoreductase domain protein; Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; SPTR: uncharacterized protein; manually curated; PFAM: Oxidoreductase, NAD-binding Rossmann fold; Zinc-binding dehydrogenase YP_004162003.1 KEGG: dfe:Dfer_3368 hypothetical protein; SPTR: uncharacterized protein YP_004162004.1 KEGG: esa:ESA_01185 hypothetical protein; SPTR: uncharacterized protein YP_004162005.1 InterPro IPR002509; KEGG: bge:BC1002_0559 polysaccharide deacetylase; PFAM: polysaccharide deacetylase; SPTR: uncharacterized protein; PFAM: polysaccharide deacetylase YP_004162006.1 COGs: COG1216 glycosyltransferase; InterPro IPR001173; KEGG: tit:Thit_0646 glycosyl transferase 2; PFAM: glycosyl transferase 2; SPTR: uncharacterized protein; PFAM: glycosyl transferase 2 YP_004162007.1 COGs: COG2244 Membrane protein involved in the export of O-antigen and teichoic acid; InterPro IPR002797; KEGG: mst:Msp_0066 polysaccharide biosynthesis protein; PFAM: polysaccharide biosynthesis protein; SPTR: uncharacterized protein; PFAM: polysaccharide biosynthesis protein YP_004162008.1 COGs: COG0381 UDP-N-acetylglucosamine 2-epimerase; InterPro IPR003331; KEGG: bfs:BF0744 UDP-GlcNAc 2-epimerase; PFAM: UDP-N-acetylglucosamine 2-epimerase; PRIAM: UDP-N-acetylglucosamine 2-epimerase; SPTR: UDP-N-acetylglucosamine 2-epimerase; TIGRFAM: UDP-N-acetylglucosamine 2-epimerase; PFAM: UDP-N-acetylglucosamine 2-epimerase; TIGRFAM: UDP-N-acetylglucosamine 2-epimerase YP_004162009.1 COGs: COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase; InterPro IPR001732: IPR014026: IPR014027: IPR017476; KEGG: bfs:BF0743 UDP-ManNAc dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase; PRIAM: UDP-glucose 6-dehydrogenase; SPTR: uncharacterized protein; TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase, NAD binding domain; UDP-glucose/GDP-mannose dehydrogenase, central domain; UDP-glucose/GDP-mannose dehydrogenase, UDP binding domain; TIGRFAM: nucleotide sugar dehydrogenase YP_004162010.1 InterPro IPR010570; KEGG: bfs:BF0732 transcriptional regulator; PFAM: protein of unknown function DUF1141; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF1141) YP_004162011.1 InterPro IPR006645; KEGG: bfs:BF0731 transcriptional regulator; PFAM: NGN domain-containing protein; SPTR: transcriptional regulator UpxY homolog; manually curated; PFAM: Transcription termination factor nusG YP_004162013.1 KEGG: bld:BLi03354 ComP; SPTR: uncharacterized protein YP_004162014.1 COGs: COG5545 P-loop ATPase and inactivated derivatives; InterPro IPR014907: IPR007936; KEGG: bfr:BF3670 hypothetical protein; PFAM: VirE; virulence-associated E family protein; SPTR: uncharacterized protein; PFAM: VirE N-terminal domain; Virulence-associated protein E YP_004162015.1 KEGG: bfs:BF3472 hypothetical protein; SPTR: uncharacterized protein YP_004162016.1 InterPro IPR000119: IPR005902; KEGG: bfs:BF3473 hypothetical protein; PFAM: histone family protein DNA-binding protein; SPTR: uncharacterized protein; TIGRFAM: DNA-binding protein; manually curated; PFAM: Bacterial DNA-binding protein; TIGRFAM: DNA-binding protein, histone-like YP_004162017.1 KEGG: bvu:BVU_2198 hypothetical protein; SPTR: uncharacterized protein YP_004162018.1 InterPro IPR012944; KEGG: bvu:BVU_0390 hypothetical protein; PFAM: RagB/SusD domain protein; SPTR: SusD/RagB family protein; PFAM: SusD family YP_004162019.1 InterPro IPR011662: IPR012910: IPR000531; KEGG: bvu:BVU_0389 hypothetical protein; PFAM: TonB-dependent receptor; TonB-dependent receptor plug; Secretin/TonB short domain; SPTR: outer membrane protein, probably involved in nutrient binding; PFAM: TonB-dependent Receptor Plug Domain; TonB dependent receptor; Secretin and TonB N terminus short domain YP_004162020.1 COGs: COG3712 Fe2+-dicitrate sensor membrane component; InterPro IPR012373: IPR006860; KEGG: bvu:BVU_0388 anti-sigma factor; PFAM: FecR protein; SPTR: uncharacterized protein; PFAM: FecR protein YP_004162021.1 COGs: COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog; InterPro IPR014284: IPR014327: IPR007627: IPR013249; KEGG: bvu:BVU_0387 RNA polymerase ECF-type sigma factor; PFAM: Sigma-70 region 4 type 2; sigma-70 region 2 domain protein; SPTR: uncharacterized protein; TIGRFAM: RNA polymerase sigma-70 factor; RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; RNA polymerase sigma-70 factor, Bacteroides expansion family 1 YP_004162022.1 COGs: COG0540 Aspartate carbamoyltransferase catalytic chain; InterPro IPR006130: IPR002082: IPR006132: IPR006131; KEGG: bth:BT_0742 aspartate carbamoyltransferase catalytic subunit; PFAM: aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; PRIAM: Aspartate carbamoyltransferase; SPTR: Aspartate carbamoyltransferase; TIGRFAM: aspartate carbamoyltransferase; PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; TIGRFAM: aspartate carbamoyltransferase YP_004162023.1 COGs: COG1781 Aspartate carbamoyltransferase regulatory subunit; InterPro IPR002801: IPR020545: IPR020542; KEGG: bfs:BF2261 aspartate carbamoyltransferase regulatory subunit; PFAM: Aspartate carbamoyltransferase regulatory subunit-like; SPTR: Aspartate carbamoyltransferase regulatory chain; TIGRFAM: aspartate carbamoyltransferase, regulatory subunit; PFAM: Aspartate carbamoyltransferase regulatory chain, metal binding domain; Aspartate carbamoyltransferase regulatory chain, allosteric domain; TIGRFAM: aspartate carbamoyltransferase, regulatory subunit YP_004162024.1 COGs: COG1853 Conserved protein/domain typically associated with flavoprotein oxygenase DIM6/NTAB family; InterPro IPR002563; KEGG: bfr:BF2206 flavoredoxin; PFAM: flavin reductase domain protein FMN-binding; SPTR: uncharacterized protein; PFAM: Flavin reductase like domain YP_004162025.1 KEGG: bfs:BF2259 hypothetical protein; SPTR: uncharacterized protein YP_004162026.1 COGs: COG0112 glycine/serine hydroxymethyltransferase; InterPro IPR019798: IPR001085; KEGG: bvu:BVU_3341 serine hydroxymethyltransferase; PFAM: glycine hydroxymethyltransferase; PRIAM: glycine hydroxymethyltransferase; SPTR: Serine hydroxymethyltransferase; PFAM: Serine hydroxymethyltransferase YP_004162027.1 COGs: COG2759 formyltetrahydrofolate synthetase; InterPro IPR020628: IPR000559; KEGG: bth:BT_0737 formate--tetrahydrofolate ligase; PFAM: formate-tetrahydrofolate ligase FTHFS; PRIAM: formate--tetrahydrofolate ligase; SPTR: uncharacterized protein; PFAM: formate--tetrahydrofolate ligase YP_004162028.1 InterPro IPR017936: IPR000866; KEGG: pru:PRU_2053 hypothetical protein; PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; SPTR: uncharacterized protein; PFAM: Redoxin YP_004162030.1 KEGG: bfr:BF2200 hypothetical protein; SPTR: uncharacterized protein YP_004162031.1 COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661: IPR003594: IPR005467: IPR004358; KEGG: bfs:BF2253 two component system sensor histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: uncharacterized protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain YP_004162032.1 COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR005829: IPR001789: IPR001867; KEGG: bfs:BF2252 two component system response regulator; PFAM: response regulator receiver; transcriptional regulator domain-containing protein; SMART: response regulator receiver; SPTR: uncharacterized protein; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal YP_004162033.1 KEGG: bth:BT_0731 hypothetical protein; SPTR: uncharacterized protein YP_004162034.1 COGs: COG1091 dTDP-4-dehydrorhamnose reductase; InterPro IPR005913; KEGG: bfr:BF2195 dTDP-4-dehydrorhamnose reductase; PFAM: dTDP-4-dehydrorhamnose reductase; SPTR: dTDP-4-dehydrorhamnose reductase; PFAM: RmlD substrate binding domain; TIGRFAM: dTDP-4-dehydrorhamnose reductase YP_004162035.1 COGs: COG0224 F0F1-type ATP synthase gamma subunit; InterPro IPR000131; KEGG: bfr:BF2179 F0F1 ATP synthase subunit gamma; PFAM: H+transporting two-sector ATPase gamma subunit; SPTR: ATP synthase gamma chain; TIGRFAM: ATP synthase F1, gamma subunit; PFAM: ATP synthase; TIGRFAM: ATP synthase, F1 gamma subunit YP_004162036.1 COGs: COG0056 F0F1-type ATP synthase alpha subunit; InterProIPR020003: IPR005294: IPR004100: IPR000194: IPR 000793; KEGG: bfs:BF2234 F0F1 ATP synthase subunit alpha; PFAM: H+transporting two-sector ATPase alpha/beta subunit central region; H+transporting two-sector ATPase alpha/beta subunit domain protein; SPTR: ATP synthase subunit alpha; TIGRFAM: ATP synthase F1, alpha subunit; PFAM: ATP synthase alpha/beta family, beta-barrel domain; ATP synthase alpha/beta family, nucleotide-binding domain; ATP synthase alpha/beta chain, C terminal domain; TIGRFAM: proton translocating ATP synthase, F1 alpha subunit YP_004162037.1 COGs: COG0712 F0F1-type ATP synthase delta subunit (mitochondrial oligomycin sensitivity protein); InterPro IPR000711; KEGG: bth:BT_0717 F0F1 ATP synthase subunit delta; PFAM: H+transporting two-sector ATPase delta (OSCP) subunit; SPTR: ATP synthase F1, delta subunit; TIGRFAM: ATP synthase F1, delta subunit; PFAM: ATP synthase delta (OSCP) subunit; TIGRFAM: ATP synthase, F1 delta subunit YP_004162038.1 COGs: COG0711 F0F1-type ATP synthase subunit b; InterPro IPR005864: IPR002146; KEGG: bfs:BF2232 ATP synthase B chain; PFAM: H+transporting two-sector ATPase B/B' subunit; SPTR: ATP synthase subunit b; TIGRFAM: ATP synthase F0, B subunit; PFAM: ATP synthase B/B' CF(0); TIGRFAM: ATP synthase, F0 subunit b YP_004162039.1 InterPro IPR020537: IPR005953: IPR002379: IPR000454; KEGG: bth:BT_0715 ATP synthase C subunit; PFAM: H+transporting two-sector ATPase C subunit; SPTR: Predicted protein; TIGRFAM: ATP synthase F0, C subunit; PFAM: ATP synthase subunit C; TIGRFAM: ATP synthase, F0 subunit c YP_004162040.1 COGs: COG0356 F0F1-type ATP synthase subunit a; InterPro IPR000568; KEGG: bth:BT_0714 ATP synthase A subunit; PFAM: H+transporting two-sector ATPase A subunit; SPTR: ATP synthase subunit a; TIGRFAM: ATP synthase F0, A subunit; PFAM: ATP synthase A chain; TIGRFAM: ATP synthase subunit 6 (eukaryotes),also subunit A (prokaryotes) YP_004162041.1 KEGG: bth:BT_0713 hypothetical protein; SPTR: uncharacterized protein YP_004162042.1 COGs: COG0355 F0F1-type ATP synthase epsilon subunit (mitochondrial delta subunit); InterPro IPR020546; KEGG: bfs:BF2228 ATP synthase epsilon chain; PFAM: ATPase, F1 complex, delta/epsilon subunit-like; SPTR: Predicted protein; PFAM: ATP synthase, Delta/Epsilon chain, beta-sandwich domain; TIGRFAM: ATP synthase, F1 epsilon subunit (delta in mitochondria) YP_004162043.1 COGs: COG0055 F0F1-type ATP synthase beta subunit; InterProIPR020003: IPR003593: IPR005722: IPR004100: IPR 000194: IPR000793; KEGG: bfs:BF2227 F0F1 ATP synthase subunit beta; PFAM: H+transporting two-sector ATPase alpha/beta subunit central region; H+transporting two-sector ATPase alpha/beta subunit domain protein; SMART: AAA ATPase; SPTR: uncharacterized protein; TIGRFAM: ATP synthase F1, beta subunit; PFAM: ATP synthase alpha/beta family, beta-barrel domain; ATP synthase alpha/beta chain, C terminal domain; ATP synthase alpha/beta family, nucleotide-binding domain; TIGRFAM: ATP synthase, F1 beta subunit YP_004162044.1 InterPro IPR002143; KEGG: bth:BT_1485 hypothetical protein; SPTR: uncharacterized protein; PFAM: AhpC/TSA family YP_004162045.1 COGs: COG1087 UDP-glucose 4-epimerase; InterPro IPR005886: IPR001509; KEGG: bth:BT_0623 UDP-glucose 4-epimerase; PFAM: NAD-dependent epimerase/dehydratase; SPTR: UDP-glucose 4-epimerase; TIGRFAM: UDP-glucose 4-epimerase; PFAM: NAD dependent epimerase/dehydratase; TIGRFAM: UDP-glucose-4-epimerase YP_004162046.1 COGs: COG4657 NADH:ubiquinone oxidoreductase subunit RnfA; InterPro IPR011293: IPR003667; KEGG: bth:BT_0622 Na+-transporting NADH:ubiquinone oxidoreductase, electron transport complex protein RnfA; PFAM: RnfA-Nqr electron transport subunit; SPTR: uncharacterized protein; TIGRFAM: electron transport complex, RnfABCDGE type, A subunit; PFAM: Rnf-Nqr subunit, membrane protein; TIGRFAM: electron transport complex, RnfABCDGE type, A subunit YP_004162047.1 COGs: COG4660 NADH:ubiquinone oxidoreductase subunit RnfE; InterPro IPR010968: IPR003667; KEGG: bth:BT_0621 electron transport complex RsxE subunit; PFAM: RnfA-Nqr electron transport subunit; SPTR: uncharacterized protein; TIGRFAM: electron transport complex, RnfABCDGE type, E subunit; manually curated; PFAM: Rnf-Nqr subunit, membrane protein; TIGRFAM: electron transport complex, RnfABCDGE type, E subunit YP_004162048.1 COGs: COG4659 NADH:ubiquinone oxidoreductase subunit RnfG; InterPro IPR010209: IPR007329; KEGG: bfs:BF2616 electron transport complex protein RnfG; PFAM: FMN-binding domain protein; SPTR: uncharacterized protein; TIGRFAM: electron transport complex, RnfABCDGE type, G subunit; manually curated; PFAM: FMN-binding domain; TIGRFAM: electron transport complex, RnfABCDGE type, G subunit YP_004162049.1 COGs: COG4658 NADH:ubiquinone oxidoreductase subunit RnfD; InterPro IPR011303: IPR004338; KEGG: bth:BT_0619 Na+-transporting NADH:ubiquinone oxidoreductase, electron transport complex protein RnfD; PFAM: NQR2 and RnfD family protein; SPTR: uncharacterized protein; TIGRFAM: electron transport complex, RnfABCDGE type, D subunit; PFAM: NQR2, RnfD, RnfE family; TIGRFAM: electron transport complex, RnfABCDGE type, D subunit YP_004162050.1 COGs: COG4656 NADH:ubiquinone oxidoreductase subunit RnfC; InterProIPR017900: IPR017896: IPR010208: IPR011538: IPR 019554; KEGG: bfs:BF2618 electron transport complex protein; PFAM: Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; Soluble ligand binding domain; SPTR: uncharacterized protein; TIGRFAM: electron transport complex, RnfABCDGE type, C subunit; PFAM: Respiratory-chain NADH dehydrogenase 51 Kd subunit; SLBB domain; TIGRFAM: electron transport complex, RnfABCDGE type, C subunit YP_004162051.1 COGs: COG2878 NADH:ubiquinone oxidoreductase subunit RnfB; InterPro IPR017900: IPR017896: IPR010207: IPR007202; KEGG: bth:BT_0617 ferredoxin; PFAM: Fe-S cluster domain protein; SPTR: uncharacterized protein; TIGRFAM: electron transport complex, RnfABCDGE type, B subunit; PFAM: Fe-S cluster; 4Fe-4S binding domain; TIGRFAM: electron transport complex, RnfABCDGE type, B subunit YP_004162052.1 InterPro IPR007359; KEGG: bth:BT_0616 hypothetical protein; PFAM: Positive regulator of sigma(E) RseC/MucC; SPTR: uncharacterized protein; manually curated; PFAM: Positive regulator of sigma(E), RseC/MucC YP_004162053.1 KEGG: bfr:BF2601 hypothetical protein; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF3078) YP_004162054.1 COGs: COG0504 CTP synthase (UTP-ammonia lyase); InterPro IPR017926: IPR004468: IPR017456: IPR000991; KEGG: bth:BT_0590 CTP synthetase; PFAM: CTP synthase-like; glutamine amidotransferase class-I; PRIAM: CTP synthase; SPTR: CTP synthase; TIGRFAM: CTP synthase; PFAM: Glutamine amidotransferase class-I; CTP synthase N-terminus; TIGRFAM: CTP synthase YP_004162055.1 COGs: COG0706 Preprotein translocase subunit YidC; InterPro IPR019998: IPR020001: IPR001708; KEGG: bfr:BF2603 inner membrane protein translocase component YidC; PFAM: 60 kDa inner membrane insertion protein; SPTR: uncharacterized protein; TIGRFAM: membrane protein insertase, YidC/Oxa1 family; membrane protein insertase, YidC/Oxa1 family domain containing; PFAM: 60Kd inner membrane protein; TIGRFAM: membrane protein insertase, YidC/Oxa1 family, C-terminal domain; membrane protein insertase, YidC/Oxa1 family, N-terminal domain YP_004162056.1 COGs: COG0534 Na+-driven multidrug efflux pump; InterPro IPR002528; KEGG: bfs:BF2626 transpor-related membrane protein; PFAM: multi antimicrobial extrusion protein MatE; SPTR: uncharacterized protein; TIGRFAM: MATE efflux family protein; PFAM: MatE; TIGRFAM: efflux protein, MATE family YP_004162057.1 COGs: COG1506 Dipeptidyl aminopeptidase/acylaminoacyl-peptidase; InterPro IPR011659; KEGG: bth:BT_0587 prolyl oligopeptidase; PFAM: hypothetical protein; SPTR: uncharacterized protein; manually curated; PFAM: Prolyl oligopeptidase; Dipeptidyl peptidase IV (DPP IV) N-terminal region; WD40-like Beta Propeller Repeat YP_004162058.1 COGs: COG1074 ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains); InterPro IPR014016: IPR014017: IPR000212; KEGG: bth:BT_1054 ATP-dependent helicase; PFAM: UvrD/REP helicase; SPTR: uncharacterized protein; PFAM: UvrD/REP helicase YP_004162059.1 KEGG: hsl:OE5371R hypothetical protein YP_004162060.1 KEGG: bth:BT_1057 hypothetical protein; SPTR: uncharacterized protein YP_004162061.1 COGs: COG0642 Signal transduction histidine kinase; InterProIPR001789: IPR003661: IPR003594: IPR005467: IPR 004358; KEGG: bfs:BF2190 two component system histidine kinase/response regulator fusion protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; SMART: response regulator receiver; histidine kinase A domain protein; ATP-binding region ATPase domain protein; SPTR: uncharacterized protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain YP_004162062.1 COGs: COG0451 Nucleoside-diphosphate-sugar epimerase; InterPro IPR001509; KEGG: bth:BT_1059 UDP-glucose 4-epimerase; PFAM: NAD-dependent epimerase/dehydratase; SPTR: uncharacterized protein; PFAM: NAD dependent epimerase/dehydratase YP_004162063.1 COGs: COG1475 transcriptional regulator protein; KEGG: bth:BT_1069 transcriptional regulator; SPTR: uncharacterized protein; PFAM: ParB-like nuclease domain YP_004162064.1 COGs: COG3969 phosphoadenosine phosphosulfate sulfotransferase; InterPro IPR002500; KEGG: bth:BT_1070 hypothetical protein; PFAM: phosphoadenosine phosphosulfate reductase; SPTR: uncharacterized protein; PFAM: Domain of unknown function (DUF3440); phosphoadenosine phosphosulfate reductase YP_004162065.1 KEGG: bfs:BF2179 hypothetical protein; SPTR: uncharacterized protein YP_004162066.1 COGs: COG0738 Fucose permease; InterPro IPR005275: IPR011701; KEGG: bvu:BVU_2606 fucose permease; PFAM: major facilitator superfamily MFS_1; SPTR: L-fucose:H+ symporter permease; TIGRFAM: L-fucose transporter; PFAM: Major Facilitator Superfamily; TIGRFAM: L-fucose:H+ symporter permease YP_004162067.1 COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004839; KEGG: bfs:BF2110 amino acid transferase; PFAM: aminotransferase class I and II; SPTR: uncharacterized protein; PFAM: Aminotransferase class I and II YP_004162068.1 KEGG: cpy:Cphy_0005 DNA gyrase, B subunit; SPTR: Predicted protein YP_004162069.1 KEGG: bth:BT_2309 hypothetical protein; SPTR: uncharacterized protein YP_004162070.1 COGs: COG1475 transcriptional regulator protein; KEGG: bth:BT_2310 hypothetical protein; SPTR: transcriptional regulator YP_004162071.1 KEGG: bth:BT_2315 hypothetical protein; SPTR: uncharacterized protein YP_004162072.1 KEGG: bth:BT_2316 hypothetical protein; SPTR: uncharacterized protein YP_004162073.1 KEGG: bth:BT_2317 hypothetical protein; SPTR: uncharacterized protein YP_004162074.1 COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR018060: IPR000005; KEGG: bth:BT_2320 transcription regulator; PFAM: helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: Transcription regulator; PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family YP_004162075.1 COGs: COG4584 Transposase and inactivated derivatives; InterPro IPR001584; KEGG: bvu:BVU_3767 transposase; PFAM: Integrase catalytic region; SPTR: ISPsy14, transposase; PFAM: Integrase core domain YP_004162076.1 COGs: COG1484 DNA replication protein; InterPro IPR003593: IPR002611; KEGG: zpr:ZPR_1312 probable insertion sequence ATP-binding protein, IS21 family; PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase; SPTR: Y4pL; PFAM: IstB-like ATP binding protein YP_004162077.1 KEGG: bth:BT_2316 hypothetical protein; SPTR: uncharacterized protein YP_004162078.1 KEGG: bth:BT_2317 hypothetical protein; SPTR: uncharacterized protein YP_004162079.1 KEGG: bth:BT_2318 hypothetical protein; SPTR: uncharacterized protein YP_004162080.1 KEGG: bth:BT_2319 hypothetical protein; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF3575); OmpA family YP_004162081.1 COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR018060: IPR000005; KEGG: bth:BT_2320 transcription regulator; PFAM: helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: Transcription regulator; PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family YP_004162082.1 COGs: COG4974 Site-specific recombinase XerD; InterPro IPR002104; KEGG: bth:BT_2322 integrase; PFAM: integrase; SPTR: uncharacterized protein; PFAM: Phage integrase YP_004162083.1 KEGG: ddi:DDB_G0279679 hypothetical protein; SPTR: uncharacterized protein YP_004162084.1 KEGG: ppp:PHYPADRAFT_198836 hypothetical protein; SPTR: uncharacterized protein YP_004162085.1 KEGG: bpy:Bphyt_0054 ABC transporter related; SPTR: uncharacterized protein YP_004162086.1 KEGG: ehi:EHI_008590 hypothetical protein; SPTR: Predicted protein YP_004162087.1 COGs: COG1670 Acetyltransferase including N-acetylase of ribosomal protein; InterPro IPR000182; KEGG: bth:BT_1079 acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: uncharacterized protein; PFAM: Acetyltransferase (GNAT) family YP_004162088.1 KEGG: bfs:BF2107 transmembrane protein; SPTR: uncharacterized protein YP_004162089.1 COGs: COG0353 Recombinational DNA repair protein (RecF pathway); InterPro IPR015967: IPR006154: IPR000093: IPR006171; KEGG: bth:BT_1081 recombination protein RecR; PFAM: Zinc finger C4-type, RecR; TOPRIM domain-containing protein; SMART: Toprim sub domain-containing protein; SPTR: uncharacterized protein; TIGRFAM: recombination protein RecR; PFAM: Toprim domain; RecR protein; TIGRFAM: recombination protein RecR YP_004162090.1 COGs: COG0218 GTPase; InterPro IPR019987: IPR002917; KEGG: bfr:BF2048 ribosome biogenesis GTP-binding protein YsxC; PFAM: GTP-binding protein HSR1-related; SPTR: Probable GTP-binding protein engB; TIGRFAM: ribosome biogenesis GTP-binding protein YsxC; PFAM: GTPase of unknown function; TIGRFAM: ribosome biogenesis GTP-binding protein YsxC/EngB; small GTP-binding protein domain YP_004162091.1 KEGG: bth:BT_1084 hypothetical protein; SPTR: uncharacterized protein YP_004162092.1 COGs: COG0019 Diaminopimelate decarboxylase; InterPro IPR005730: IPR000183; KEGG: bth:BT_0674 carboxynorspermidine decarboxylase; PFAM: Orn/DAP/Arg decarboxylase 2; SPTR: Carboxynorspermidine decarboxylase; TIGRFAM: carboxynorspermidine decarboxylase; PFAM: Pyridoxal-dependent decarboxylase, C-terminal sheet domain; Pyridoxal-dependent decarboxylase, pyridoxal binding domain; TIGRFAM: carboxynorspermidine decarboxylase YP_004162093.1 COGs: COG0210 Superfamily I DNA and RNA helicase; InterPro IPR014016: IPR014017: IPR000212; KEGG: bfs:BF2555 helicase; PFAM: UvrD/REP helicase; SPTR: uncharacterized protein; PFAM: UvrD/REP helicase YP_004162094.1 COGs: COG0605 Superoxide dismutase; InterPro IPR019833: IPR001189: IPR019831: IPR019832; KEGG: bfr:BF2527 superoxide dismutase; PFAM: Manganese/iron superoxide dismutase-like; SPTR: Superoxide dismutase; PFAM: Iron/manganese superoxide dismutases, alpha-hairpin domain; Iron/manganese superoxide dismutases, C-terminal domain YP_004162095.1 COGs: COG0352 Thiamine monophosphate synthase; InterPro IPR003733; KEGG: bfs:BF2564 thiamine phosphate pyrophosphorylase; PFAM: thiamine monophosphate synthase; SPTR: uncharacterized protein; PFAM: Thiamine monophosphate synthase/TENI YP_004162096.1 COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661: IPR003594: IPR005467: IPR004358; KEGG: bth:BT_1833 two-component system sensor histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: uncharacterized protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain YP_004162097.1 COGs: COG0574 phosphoenolpyruvate synthase/pyruvate phosphate dikinase; InterProIPR018274: IPR000121: IPR010121: IPR002192: IPR 008279; KEGG: bfr:BF2538 pyruvate phosphate dikinase; PFAM: pyruvate phosphate dikinase PEP/pyruvate-binding; PEP-utilising protein mobile region; PEP-utilizing protein; PRIAM: Pyruvate, phosphate dikinase; SPTR: uncharacterized protein; TIGRFAM: pyruvate, phosphate dikinase; PFAM: PEP-utilising enzyme, TIM barrel domain; PEP-utilising enzyme, mobile domain; Pyruvate phosphate dikinase, PEP/pyruvate binding domain; TIGRFAM: pyruvate, phosphate dikinase YP_004162098.1 COGs: COG2265 SAM-dependent methyltransferase related to tRNA (uracil-5-)-methyltransferase; InterPro IPR010280: IPR002792: IPR001566; KEGG: bfs:BF2568 RNA methyltransferase; PFAM: (uracil-5)-methyltransferase; deoxyribonuclease/rho motif-related TRAM; SPTR: 23S rRNA (uracil-5-)-methyltransferase RumA; TIGRFAM: RNA methyltransferase, TrmA family; manually curated; PFAM: tRNA (uracil-5-)-methyltransferase; TRAM domain; TIGRFAM: 23S rRNA (uracil-5-)-methyltransferase RumA YP_004162099.1 COGs: COG0564 Pseudouridylate synthase 23S RNA-specific; InterPro IPR006224: IPR002942: IPR006225: IPR006145; KEGG: bth:BT_0642 RNA pseudouridylate synthase; PFAM: pseudouridine synthase; RNA-binding S4 domain protein; SPTR: Pseudouridine synthase; TIGRFAM: pseudouridine synthase, RluA family; PFAM: RNA pseudouridylate synthase; TIGRFAM: pseudouridine synthase, RluA family YP_004162100.1 KEGG: bfs:BF2570 lipoprotein; SPTR: uncharacterized protein YP_004162101.1 COGs: COG0286 type I restriction-modification system methyltransferase subunit; InterPro IPR002052: IPR004546: IPR003356: IPR002296; KEGG: fjo:Fjoh_4393 type I restriction-modification system, M subunit; PFAM: N-6 DNA methylase; SPTR: type I restriction-modification system, M subunit; TIGRFAM: type I restriction-modification system, M subunit; PFAM: N-6 DNA methylase; HsdM N-terminal domain; TIGRFAM: type I restriction system adenine methylase (hsdM) YP_004162102.1 COGs: COG4804 conserved hypothetical protein; InterPro IPR009362; KEGG: hap:HAPS_1837 cytoplasmic protein; PFAM: protein of unknown function DUF1016; SPTR: cytoplasmic protein; PFAM: Protein of unknown function (DUF1016) YP_004162103.1 KEGG: pay:PAU_03969 anticodon nuclease prrc; SPTR: uncharacterized protein YP_004162104.1 COGs: COG0610 type I site-specific restriction-modification system R (restriction) subunit and related helicase; InterProIPR014001: IPR014021: IPR004473: IPR007409: IPR 006935; KEGG: fjo:Fjoh_4396 HsdR family type I site-specific deoxyribonuclease; PFAM: type III restriction protein res subunit; protein of unknown function DUF450; PRIAM: type I site-specific deoxyribonuclease; SMART: DEAD-like helicase; SPTR: type I site-specific deoxyribonuclease, HsdR family; TIGRFAM: type I site-specific deoxyribonuclease, HsdR family; PFAM: type I restriction enzyme R protein N terminus (HSDR_N); type I restriction and modification enzyme - subunit R C terminal; type III restriction enzyme, res subunit; TIGRFAM: type I site-specific deoxyribonuclease, HsdR family YP_004162105.1 COGs: COG0350 methylated DNA-protein cysteine methyltransferase; InterPro IPR014048; KEGG: bvu:BVU_3221 methylated-DNA-protein-cysteine methyltransferase; PFAM: methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding; SPTR: uncharacterized protein; TIGRFAM: methylated-DNA/protein-cysteine methyltransferase; PFAM: 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain; 6-O-methylguanine DNA methyltransferase, DNA binding domain; TIGRFAM: O-6-methylguanine DNA methyltransferase YP_004162106.1 COGs: COG0350 methylated DNA-protein cysteine methyltransferase; InterProIPR018062: IPR001497: IPR018060: IPR014048: IPR 000005; KEGG: phe:Phep_0721 methylated-DNA/protein-cysteine methyltransferase; PFAM: methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding; helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: uncharacterized protein; TIGRFAM: methylated-DNA/protein-cysteine methyltransferase; PFAM: 6-O-methylguanine DNA methyltransferase, DNA binding domain; Bacterial regulatory helix-turn-helix proteins, AraC family; TIGRFAM: O-6-methylguanine DNA methyltransferase YP_004162107.1 KEGG: bfs:BF2565 hypothetical protein; SPTR: uncharacterized protein; PFAM: Autotransporter beta-domain YP_004162108.1 InterPro IPR005902; KEGG: bth:BT_4601 hypothetical protein; SPTR: uncharacterized protein; TIGRFAM: DNA-binding protein; PFAM: Bacterial DNA-binding protein; TIGRFAM: DNA-binding protein, histone-like YP_004162109.1 COGs: COG0420 DNA repair exonuclease; InterPro IPR004593: IPR004843; KEGG: pdi:BDI_1730 exonuclease; PFAM: metallophosphoesterase; SPTR: uncharacterized protein; TIGRFAM: nuclease SbcCD, D subunit; PFAM: Calcineurin-like phosphoesterase; type 5 capsule protein repressor C terminal; TIGRFAM: exonuclease SbcD YP_004162110.1 COGs: COG0419 ATPase involved in DNA repair; InterPro IPR002078; KEGG: bvu:BVU_0486 ATP-dependent exonuclease SbcC; SPTR: uncharacterized protein; TIGRFAM: exonuclease SbcC YP_004162111.1 COGs: COG0024 methionine aminopeptidase; InterPro IPR002467: IPR000994: IPR001714; KEGG: bfs:BF2576 aminopeptidase; PFAM: peptidase M24; SPTR: methionine aminopeptidase; TIGRFAM: methionine aminopeptidase, type I; PFAM: Metallopeptidase M24; TIGRFAM: methionine aminopeptidase, type I YP_004162112.1 COGs: COG1322 conserved hypothetical protein; InterPro IPR003798; KEGG: pgn:PGN_0031 hypothetical protein; PFAM: protein of unknown function DUF195; SPTR: uncharacterized protein; PFAM: RmuC family YP_004162113.1 COGs: COG0503 Adenine/guanine phosphoribosyltransferase and related PRPP-binding protein; InterPro IPR010079: IPR000836; KEGG: bvu:BVU_2532 xanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; SPTR: Xanthine phosphoribosyltransferase; TIGRFAM: xanthine phosphoribosyltransferase; PFAM: phosphoribosyl transferase domain; TIGRFAM: xanthine phosphoribosyltransferase YP_004162114.1 COGs: COG2233 Xanthine/uracil permease; InterPro IPR006042: IPR017588: IPR006043; KEGG: bvu:BVU_2531 purine permease; PFAM: Xanthine/uracil/vitamin C permease; SPTR: uncharacterized protein; TIGRFAM: xanthine permease; uracil-xanthine permease; PFAM: Permease; TIGRFAM: uracil-xanthine permease; xanthine permease YP_004162115.1 COGs: COG3004 Na+/H+ antiporter; InterPro IPR004670; KEGG: bfs:BF2579 Na+/H+ antiporter; PFAM: Na+/H+ antiporter NhaA; SPTR: Na+/H+ antiporter NhaA; TIGRFAM: Na+/H+ antiporter NhaA; PFAM: Na+/H+ antiporter 1; TIGRFAM: Na+/H+ antiporter NhaA; TC 2.A.33.1.1 YP_004162116.1 COGs: COG0481 Membrane GTPase LepA; InterProIPR005225: IPR006297: IPR000795: IPR004161: IPR 000640: IPR013842; KEGG: bth:BT_0632 GTP-binding protein LepA; PFAM: GTP-binding protein LepA domain protein; protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; elongation factor G domain-containing protein; SPTR: GTP-binding protein lepA; TIGRFAM: GTP-binding protein LepA; small GTP-binding protein; PFAM: Elongation factor Tu domain 2; Elongation factor G C-terminus; Elongation factor Tu GTP binding domain; GTP-binding protein LepA C-terminus; TIGRFAM: GTP-binding protein LepA; small GTP-binding protein domain YP_004162117.1 InterPro IPR019707; KEGG: bfs:BF2582 hypothetical protein; PFAM: Protein of unknown function DUF2582; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF2582) YP_004162118.1 InterPro IPR010181; KEGG: bfs:BF2583 hypothetical protein; PFAM: C_GCAxxG_C_C family protein; SPTR: uncharacterized protein; TIGRFAM: C_GCAxxG_C_C family protein; PFAM: redox-active protein (C_GCAxxG_C_C); TIGRFAM: C_GCAxxG_C_C family probable redox protein YP_004162119.1 COGs: COG0708 Exonuclease III; InterPro IPR020847: IPR004808: IPR000097: IPR005135; KEGG: bth:BT_0630 exodeoxyribonuclease; PFAM: Endonuclease/exonuclease/phosphatase; PRIAM: DNA-(apurinic or apyrimidinic site) lyase; SPTR: uncharacterized protein; TIGRFAM: exodeoxyribonuclease III Xth; exodeoxyribonuclease III; PFAM: Endonuclease/Exonuclease/phosphatase; TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III (xth) YP_004162120.1 COGs: COG1914 Mn2+ and Fe2+ transporter of the NRAMP family; InterPro IPR001046; KEGG: bfs:BF2586 manganese transport-related membrane protein; PFAM: natural resistance-associated macrophage protein; SPTR: uncharacterized protein; PFAM: Natural resistance-associated macrophage protein; TIGRFAM: NRAMP (natural resistance-associated macrophage protein) metal ion transporters YP_004162121.1 KEGG: bth:BT_0628 hypothetical protein; SPTR: uncharacterized protein YP_004162122.1 COGs: COG0217 conserved hypothetical protein; InterPro IPR002876; KEGG: bth:BT_0627 hypothetical protein; PFAM: protein of unknown function DUF28; SPTR: UPF0082 protein HMPREF0969_00623; PFAM: Domain of unknown function DUF28; TIGRFAM: DNA-binding regulatory protein, YebC/PmpR family YP_004162123.1 COGs: COG0072 Phenylalanyl-tRNA synthetase beta subunit; InterProIPR002547: IPR005121: IPR004532: IPR005146: IPR 005147; KEGG: bfr:BF2565 phenylalanyl-tRNA synthetase subunit beta; PFAM: B3/4 domain protein; tRNA-binding protein; tRNA synthetase B5; ferredoxin-fold anticodon-binding; SPTR: uncharacterized protein; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit; PFAM: tRNA synthetase B5 domain; Ferredoxin-fold anticodon binding domain; B3/4 domain; tRNA binding domain; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit, non-spirochete bacterial YP_004162124.1 COGs: COG0321 Lipoate-protein ligase B; InterPro IPR020605: IPR000544: IPR004143; KEGG: bfr:BF2034 lipoate-protein ligase B; PFAM: biotin/lipoate A/B protein ligase; PRIAM: Lipoyl(octanoyl) transferase; SPTR: Octanoyltransferase; TIGRFAM: lipoate-protein ligase B; PFAM: Biotin/lipoate A/B protein ligase; TIGRFAM: lipoate-protein ligase B YP_004162125.1 KEGG: pic:PICST_67318 hypothetical protein; SPTR: uncharacterized protein YP_004162126.1 KEGG: dse:Dsec_GM21914 GM21914 gene product from transcript GM21914-RA; SPTR: uncharacterized protein YP_004162127.1 KEGG: hut:Huta_2386 transcriptional regulator, TrmB; SPTR: uncharacterized protein YP_004162128.1 COGs: COG0463 glycosyltransferase involved in cell wall biogenesis; InterPro IPR001173; KEGG: pdi:BDI_1344 glycosyl transferase; PFAM: glycosyl transferase 2; SPTR: uncharacterized protein; PFAM: glycosyl transferase 2 YP_004162129.1 COGs: COG1032 Fe-S oxidoreductase; InterPro IPR006638: IPR006158: IPR007197; KEGG: pdi:BDI_1345 Fe-S oxidoreductase; PFAM: radical SAM protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: Fe-S oxidoreductase; PFAM: Radical SAM superfamily; B12 binding domain YP_004162130.1 COGs: COG0463 glycosyltransferase involved in cell wall biogenesis; InterPro IPR001173; KEGG: fsu:Fisuc_0503 glycosyl transferase 2; PFAM: glycosyl transferase 2; SPTR: glycosyl transferase 2; PFAM: glycosyl transferase 2 YP_004162131.1 KEGG: pdi:BDI_1843 hypothetical protein; SPTR: uncharacterized protein YP_004162132.1 COGs: COG0463 glycosyltransferase involved in cell wall biogenesis; InterPro IPR001173; KEGG: bth:BT_1648 glycosyltransferase; PFAM: glycosyl transferase 2; SPTR: glycoside transferase 2; PFAM: glycosyl transferase 2 YP_004162133.1 COGs: COG0110 Acetyltransferase (isoleucine patch superfamily); InterPro IPR018357: IPR001451; KEGG: sli:Slin_0720 acetyltransferase (isoleucine patch superfamily)-like protein; SPTR: Acetyltransferase (Isoleucine patch superfamily)-like protein YP_004162134.1 InterPro IPR007074; KEGG: cpf:CPF_0603 hypothetical protein; PFAM: LicD family protein; SPTR: uncharacterized protein; PFAM: LICD Protein Family YP_004162135.1 KEGG: nth:Nther_2746 hypothetical protein; SPTR: uncharacterized protein YP_004162136.1 COGs: COG2843 protein of poly-gamma-glutamate biosynthesis (capsule formation); InterPro IPR019079; KEGG: fsu:Fisuc_2666 capsule synthesis protein, CapA; PFAM: Capsule synthesis protein, CapA; SPTR: Capsule synthesis protein, CapA; PFAM: Bacterial capsule synthesis protein PGA_cap YP_004162137.1 COGs: COG2423 ornithine cyclodeaminase mu-crystallin homolog; InterPro IPR003462; KEGG: pdi:BDI_1464 ornithine cyclodeaminase; PFAM: ornithine cyclodeaminase/mu-crystallin; SPTR: ornithine cyclodeaminase; PFAM: Ornithine cyclodeaminase/mu-crystallin family YP_004162138.1 COGs: COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; InterPro IPR004838: IPR004839: IPR001176; KEGG: pdi:BDI_1415 hemolysin erythrocyte lysis protein 2; PFAM: aminotransferase class I and II; PRIAM: Histidinol-phosphate transaminase; SPTR: Hemolysin erythrocyte lysis protein 2; PFAM: Nucleotidyl transferase; Aminotransferase class I and II YP_004162140.1 KEGG: ccs:CCNA_03092 cytochrome P450 IVA5; SPTR: uncharacterized protein YP_004162141.1 COGs: COG5545 P-loop ATPase and inactivated derivatives; InterPro IPR014907; KEGG: pru:PRU_1575 hypothetical protein; PFAM: VirE; SPTR: uncharacterized protein; PFAM: VirE N-terminal domain; Virulence-associated protein E YP_004162142.1 KEGG: bth:BT_1170 hypothetical protein; SPTR: Predicted protein YP_004162143.1 InterPro IPR005902; KEGG: bvu:BVU_3915 hypothetical protein; SPTR: uncharacterized protein; TIGRFAM: DNA-binding protein; TIGRFAM: DNA-binding protein, histone-like YP_004162144.1 KEGG: bfs:BF0755 hypothetical protein; SPTR: uncharacterized protein YP_004162145.1 COGs: COG2148 Sugar transferase involved in lipopolysaccharide synthesis; InterPro IPR003362; KEGG: pdi:BDI_1355 capsular polysaccharide biosynthesis glycosyltransferase; PFAM: sugar transferase; SPTR: uncharacterized protein; PFAM: Bacterial sugar transferase YP_004162146.1 InterPro IPR010570; KEGG: bfs:BF0732 transcriptional regulator; PFAM: protein of unknown function DUF1141; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF1141) YP_004162147.1 InterPro IPR006645; KEGG: bfs:BF0731 transcriptional regulator; PFAM: NGN domain-containing protein; SPTR: transcriptional regulator UpxY homolog; manually curated; PFAM: Transcription termination factor nusG YP_004162149.1 KEGG: bfs:BF2082 hypothetical protein; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF3298) YP_004162150.1 COGs: COG0357 S-adenosylmethionine-dependent methyltransferase involved in cell division; InterPro IPR003682; KEGG: bfs:BF2081 16S rRNA methyltransferase GidB; PFAM: glucose inhibited division protein; SPTR: Ribosomal RNA small subunit methyltransferase G; TIGRFAM: methyltransferase GidB; PFAM: rRNA small subunit methyltransferase G; TIGRFAM: 16S rRNA methyltransferase GidB YP_004162151.1 COGs: COG0491 Zn-dependent hydrolase including glyoxylase; KEGG: bfr:BF2026 metallo-beta-lactamase; SPTR: uncharacterized protein; PFAM: Metallo-beta-lactamase superfamily YP_004162152.1 COGs: COG1003 glycine cleavage system protein P (pyridoxal-binding) C-terminal domain; InterPro IPR003437: IPR020580; KEGG: bfs:BF2079 glycine dehydrogenase; PFAM: glycine cleavage system P-protein-like; SPTR: glycine dehydrogenase [decarboxylating]; TIGRFAM: glycine dehydrogenase; PFAM: glycine cleavage system P-protein; TIGRFAM: glycine dehydrogenase (decarboxylating) YP_004162153.1 COGs: COG1272 membrane protein hemolysin III homolog; InterPro IPR004254; KEGG: pru:PRU_2761 hemolysin III; PFAM: Hly-III family protein; SPTR: uncharacterized protein; PFAM: Haemolysin-III related; TIGRFAM: channel protein, hemolysin III family YP_004162154.1 InterPro IPR019062; KEGG: bfr:BF2023 type II restriction enzyme HpaII; PFAM: Restriction endonuclease, type II, HpaII; PRIAM: type II site-specific deoxyribonuclease; SPTR: uncharacterized protein; PFAM: HpaII restriction endonuclease YP_004162155.1 COGs: COG1739 conserved hypothetical protein; InterPro IPR020569: IPR001498; KEGG: bfs:BF2076 hypothetical protein; PFAM: Uncharacterised protein family UPF0029, Impact, N-terminal; SPTR: uncharacterized protein; manually curated; PFAM: Uncharacterized protein family UPF0029; TIGRFAM: uncharacterized protein, YigZ family YP_004162156.1 COGs: COG4198 conserved hypothetical protein; InterPro IPR008323; KEGG: bth:BT_1151 hypothetical protein; PFAM: Uncharacterised conserved protein UCP033563; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF1015) YP_004162157.1 COGs: COG1052 Lactate dehydrogenase and related dehydrogenase; InterPro IPR006139: IPR006140; KEGG: bvu:BVU_3242 D-3-phosphoglycerate dehydrogenase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; SPTR: uncharacterized protein; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain YP_004162158.1 COGs: COG1932 phosphoserine aminotransferase; InterPro IPR003248: IPR000192; KEGG: bth:BT_1153 phosphoserine aminotransferase; PFAM: aminotransferase class V; PRIAM: phosphoserine transaminase; SPTR: uncharacterized protein; TIGRFAM: phosphoserine aminotransferase; PFAM: Aminotransferase class-V; TIGRFAM: phosphoserine aminotransferase YP_004162159.1 COGs: COG0513 Superfamily II DNA and RNA helicase; InterProIPR014001: IPR001650: IPR014021: IPR011545: IPR 005580; KEGG: bfr:BF2017 ATP-independent RNA helicase; PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; DbpA RNA-binding domain protein; SMART: DEAD-like helicase; helicase domain protein; SPTR: uncharacterized protein; PFAM: Helicase conserved C-terminal domain; DbpA RNA binding domain; DEAD/DEAH box helicase YP_004162160.1 COGs: COG2871 Na+-transporting NADH:ubiquinone oxidoreductase subunit NqrF; InterProIPR001041: IPR017927: IPR010205: IPR008333: IPR 001433: IPR001709; KEGG: bth:BT_1155 Na(+)-translocating NADH-quinone reductase subunit F; PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; ferredoxin; Oxidoreductase FAD-binding domain protein; SPTR: NADH:ubiquinone oxidoreductase, F subunit; TIGRFAM: NADH:ubiquinone oxidoreductase, subunit F; PFAM: 2Fe-2S iron-sulfur cluster binding domain; Oxidoreductase FAD-binding domain; Oxidoreductase NAD-binding domain; TIGRFAM: NADH:ubiquinone oxidoreductase, Na(+)-translocating, F subunit YP_004162161.1 COGs: COG2209 Na+-transporting NADH:ubiquinone oxidoreductase subunit NqrE; InterPro IPR010967: IPR003667; KEGG: bth:BT_1156 Na(+)-translocating NADH-quinone reductase subunit E; PFAM: RnfA-Nqr electron transport subunit; SPTR: uncharacterized protein; TIGRFAM: NADH:ubiquinone oxidoreductase, subunit E; manually curated; PFAM: Rnf-Nqr subunit, membrane protein; TIGRFAM: NADH:ubiquinone oxidoreductase, Na(+)-translocating, E subunit YP_004162162.1 COGs: COG1347 Na+-transporting NADH:ubiquinone oxidoreductase subunit NqrD; InterPro IPR011292: IPR003667; KEGG: bth:BT_1157 Na(+)-translocating NADH-quinone reductase subunit D; PFAM: RnfA-Nqr electron transport subunit; SPTR: uncharacterized protein; TIGRFAM: NADH:ubiquinone oxidoreductase, subunit D; PFAM: Rnf-Nqr subunit, membrane protein; TIGRFAM: NADH:ubiquinone oxidoreductase, Na(+)-translocating, D subunit YP_004162163.1 COGs: COG2869 Na+-transporting NADH:ubiquinone oxidoreductase subunit NqrC; InterPro IPR010204: IPR007329; KEGG: bth:BT_1158 Na(+)-translocating NADH-quinone reductase subunit C; PFAM: FMN-binding domain protein; SPTR: uncharacterized protein; TIGRFAM: NADH:ubiquinone oxidoreductase, subunit C; PFAM: FMN-binding domain; TIGRFAM: NADH:ubiquinone oxidoreductase, Na(+)-translocating, C subunit YP_004162164.1 COGs: COG1805 Na+-transporting NADH:ubiquinone oxidoreductase subunit NqrB; InterPro IPR010966: IPR004338; KEGG: bth:BT_1159 Na(+)-translocating NADH-quinone reductase subunit B; PFAM: NQR2 and RnfD family protein; SPTR: uncharacterized protein; TIGRFAM: NADH:ubiquinone oxidoreductase, subunit B; PFAM: NQR2, RnfD, RnfE family; TIGRFAM: NADH:ubiquinone oxidoreductase, Na(+)-translocating, B subunit YP_004162165.1 COGs: COG1726 Na+-transporting NADH:ubiquinone oxidoreductase subunit NqrA; InterPro IPR008703; KEGG: bfr:BF2011 Na(+)-translocating NADH-quinone reductase subunit A; PFAM: Na-translocating NADH-quinone reductase subunit A; SPTR: uncharacterized protein; TIGRFAM: NADH:ubiquinone oxidoreductase, subunit A; PFAM: NQRA C-terminal domain; Na(+)-translocating NADH-quinone reductase subunit A (NQRA); TIGRFAM: NADH:ubiquinone oxidoreductase, Na(+)-translocating, A subunit YP_004162166.1 COGs: COG3579 Aminopeptidase C; InterPro IPR000169: IPR000408: IPR004134; KEGG: bfs:BF2064 aminopeptidase; PFAM: peptidase C1B bleomycin hydrolase; PRIAM: Bleomycin hydrolase; SPTR: uncharacterized protein; PFAM: peptidase C1-like family YP_004162167.1 KEGG: bfs:BF2063 hypothetical protein; SPTR: uncharacterized protein; PFAM: Surface antigen YP_004162168.1 COGs: COG1215 glycosyltransferase probably involved in cell wall biogenesis; InterPro IPR001173; KEGG: bfr:BF1995 glycosyltransferase; PFAM: glycosyl transferase 2; SPTR: two-component system sensor histidine kinase/response regulator; PFAM: glycosyl transferase 2 YP_004162169.1 COGs: COG5016 Pyruvate/oxaloacetate carboxyltransferase; InterPro IPR000891; KEGG: bvu:BVU_3346 pyruvate carboxylase subunit B; PFAM: pyruvate carboxyltransferase; PRIAM: Pyruvate carboxylase; SPTR: uncharacterized protein; PFAM: HMGL-like; Conserved carboxylase domain YP_004162170.1 COGs: COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog; InterPro IPR014284: IPR007627: IPR013249; KEGG: bfs:BF1954 RNA polymerase ECF-type sigma factor; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; SPTR: uncharacterized protein; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family YP_004162172.1 COGs: COG0612 Zn-dependent peptidase; InterPro IPR011765: IPR007863; KEGG: pdi:BDI_0963 M16 family peptidase; PFAM: peptidase M16; SPTR: uncharacterized protein; PFAM: peptidase M16 inactive domain; Insulinase (peptidase M16) YP_004162173.1 COGs: COG2860 membrane protein; InterPro IPR005115; KEGG: bvu:BVU_3350 hypothetical protein; PFAM: Uncharacterised protein family UPF0126; SPTR: uncharacterized protein; PFAM: UPF0126 domain YP_004162174.1 COGs: COG0381 UDP-N-acetylglucosamine 2-epimerase; InterPro IPR003331; KEGG: bfs:BF1948 UDP-N-acetylglucosamine 2-epimerase; PFAM: UDP-N-acetylglucosamine 2-epimerase; PRIAM: UDP-N-acetylglucosamine 2-epimerase; SPTR: UDP-N-acetylglucosamine 2-epimerase; PFAM: UDP-N-acetylglucosamine 2-epimerase; TIGRFAM: UDP-N-acetylglucosamine 2-epimerase YP_004162175.1 KEGG: bfs:BF1947 hypothetical protein; SPTR: uncharacterized protein YP_004162176.1 COGs: COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase; InterPro IPR003593: IPR003959; KEGG: bth:BT_1205 recombination factor protein RarA; PFAM: AAA ATPase central domain protein; SMART: AAA ATPase; SPTR: uncharacterized protein; PFAM: MgsA AAA+ ATPase C terminal; ATPase associated with various cellular activities (AAA) YP_004162177.1 COGs: COG1052 Lactate dehydrogenase and related dehydrogenase; InterPro IPR006140: IPR006139; KEGG: bth:BT_1207 glycerate dehydrogenase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; SPTR: glycerate dehydrogenase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain YP_004162178.1 InterPro IPR005135; KEGG: bfr:BF1993 hypothetical protein; PFAM: Endonuclease/exonuclease/phosphatase; SPTR: uncharacterized protein; PFAM: Endonuclease/Exonuclease/phosphatase YP_004162179.1 InterPro IPR012910; KEGG: cpi:Cpin_5935 TonB-dependent receptor plug; PFAM: TonB-dependent receptor plug; SPTR: transporter, outer membrane receptor (OMR) family YP_004162180.1 COGs: COG1864 DNA/RNA endonuclease G NUC1; InterPro IPR020821: IPR001604; KEGG: bth:BT_3558 endonuclease; PFAM: DNA/RNA non-specific endonuclease; SMART: Extracellular Endonuclease, subunit A; SPTR: uncharacterized protein; PFAM: DNA/RNA non-specific endonuclease YP_004162181.1 KEGG: bvu:BVU_2751 hypothetical protein; SPTR: uncharacterized protein YP_004162182.1 COGs: COG1629 Outer membrane receptor protein mostly Fe transport; InterPro IPR012910: IPR000531; KEGG: bfs:BF2044 TonB-dependent outer membrane receptor protein; PFAM: TonB-dependent receptor; TonB-dependent receptor plug; SPTR: TonB-dependent receptor; PFAM: TonB dependent receptor; TonB-dependent Receptor Plug Domain YP_004162183.1 COGs: COG0488 ATPase components of ABC transporter with duplicated ATPase domains; InterPro IPR017871: IPR003593: IPR003439; KEGG: bfs:BF2043 ABC transporter ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: uncharacterized protein; PFAM: ABC transporter; TIGRFAM: ATP-binding cassette protein, ChvD family YP_004162184.1 KEGG: pmo:Pmob_1275 GntR family transcriptional regulator; SPTR: uncharacterized protein YP_004162185.1 KEGG: fps:FP1570 hypothetical protein; SPTR: uncharacterized protein; manually curated YP_004162186.1 COGs: COG0433 ATPase; KEGG: bhy:BHWA1_01315 hypothetical protein; SPTR: uncharacterized protein; PFAM: Domain of unknown function DUF87 YP_004162187.1 KEGG: pct:PC1_3280 hypothetical protein; SPTR: uncharacterized protein YP_004162188.1 KEGG: pvi:Cvib_0491 phosphotransferase domain-containing protein; SPTR: ABC transporter; PFAM: PHP domain YP_004162189.1 InterPro IPR002052: IPR003356: IPR002296; KEGG: wsu:WS1930 hypothetical protein; PFAM: N-6 DNA methylase; SPTR: uncharacterized protein; PFAM: N-6 DNA methylase YP_004162190.1 InterPro IPR002052: IPR007409: IPR002296; KEGG: abi:Aboo_1333 protein of unknown function DUF450; PFAM: protein of unknown function DUF450; SPTR: uncharacterized protein; PFAM: N-6 DNA methylase; Eco57I restriction endonuclease YP_004162191.1 InterPro IPR001387; KEGG: fps:FP0735 DNA binding protein; PFAM: hypothetical protein; SMART: hypothetical protein; SPTR: uncharacterized protein; PFAM: Helix-turn-helix YP_004162192.1 KEGG: pdi:BDI_0746 hypothetical protein; SPTR: uncharacterized protein YP_004162193.1 KEGG: pdi:BDI_0745 hypothetical protein; SPTR: DNA binding domain, excisionase; TIGRFAM: DNA binding domain, excisionase YP_004162194.1 KEGG: pdi:BDI_0743 hypothetical protein; SPTR: uncharacterized protein YP_004162195.1 COGs: COG4974 Site-specific recombinase XerD; InterPro IPR002104; KEGG: pdi:BDI_0742 integrase; PFAM: integrase; SPTR: Integrase; PFAM: Phage integrase YP_004162196.1 COGs: COG4974 Site-specific recombinase XerD; InterPro IPR002104; KEGG: bth:BT_4022 integrase; PFAM: integrase; SPTR: Integrase; PFAM: Phage integrase YP_004162197.1 COGs: COG1629 Outer membrane receptor protein mostly Fe transport; InterPro IPR012910: IPR000531; KEGG: fps:FP1882 TonB-dependent outer membrane receptorprecursor; PFAM: TonB-dependent receptor; TonB-dependent receptor plug; SPTR: TonB-dependent outer membrane receptorprecursor; PFAM: TonB dependent receptor YP_004162199.1 KEGG: pdi:BDI_0768 hypothetical protein; SPTR: uncharacterized protein; PFAM: TonB-dependent Receptor Plug Domain YP_004162200.1 KEGG: mpe:MYPE1840 NAD-dependent DNA ligase; SPTR: Predicted protein YP_004162201.1 COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR000792; KEGG: bvu:BVU_1455 transcriptional regulator; PFAM: regulatory protein LuxR; SMART: regulatory protein LuxR; SPTR: Transcriptional regulator; PFAM: Bacterial regulatory proteins, luxR family YP_004162202.1 COGs: COG3943 Virulence protein; InterPro IPR011204; KEGG: bfs:BF1126 hypothetical protein; SPTR: uncharacterized protein YP_004162203.1 KEGG: svo:SVI_2814 exodeoxyribonuclease III; SPTR: Predicted protein YP_004162204.1 KEGG: bfs:BF2415 hypothetical protein; SPTR: Predicted protein YP_004162205.1 KEGG: cat:CA2559_00405 excisionase; SPTR: Predicted protein YP_004162206.1 KEGG: pcb:PC000112.01.0 vacuolar ATP synthase subunit h YP_004162207.1 InterPro IPR005182; KEGG: bvu:BVU_2479 hypothetical protein; PFAM: membrane-flanked domain; SPTR: uncharacterized protein; PFAM: Bacterial membrane flanked domain YP_004162208.1 KEGG: bfr:BF1380 hypothetical protein; SPTR: uncharacterized protein YP_004162209.1 KEGG: bfr:BF1975 hypothetical protein; SPTR: uncharacterized protein YP_004162210.1 KEGG: bfr:BF1974 hypothetical protein; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF1266) YP_004162211.1 KEGG: bfr:BF1973 hypothetical protein; SPTR: uncharacterized protein YP_004162212.1 KEGG: mhu:Mhun_3087 hypothetical protein; SPTR: uncharacterized protein YP_004162213.1 KEGG: bfr:BF3138 hypothetical protein; SPTR: uncharacterized protein YP_004162214.1 KEGG: pdi:BDI_3895 hypothetical protein; SPTR: uncharacterized protein; manually curated YP_004162215.1 KEGG: tle:Tlet_0675 cobalt transport protein; SPTR: Cobalt transport protein YP_004162216.1 KEGG: bfs:BF1725 hypothetical protein; SPTR: uncharacterized protein YP_004162217.1 KEGG: bfs:BF1757 transmembrane protein; SPTR: uncharacterized protein YP_004162218.1 KEGG: bfs:BF2973 hypothetical protein; SPTR: uncharacterized protein; manually curated YP_004162219.1 KEGG: bfs:BF1789 hypothetical protein; SPTR: uncharacterized protein YP_004162220.1 KEGG: cth:Cthe_2751 hypothetical protein; SPTR: uncharacterized protein YP_004162221.1 KEGG: cqu:CpipJ_CPIJ009720 alpha-mannosidase 2; SPTR: uncharacterized protein YP_004162222.1 KEGG: gym:GYMC10_1086 hypothetical protein; SPTR: uncharacterized protein YP_004162223.1 KEGG: pru:PRU_1548 hypothetical protein; SPTR: uncharacterized protein YP_004162224.1 COGs: COG2253 conserved hypothetical protein; InterPro IPR014942; KEGG: pru:PRU_1547 hypothetical protein; PFAM: Domain of unknown function DUF1814; SPTR: uncharacterized protein; PFAM: Domain of unknown function (DUF1814) YP_004162225.1 InterPro IPR001647; KEGG: bfr:BF1965 transcriptional regulator; PFAM: regulatory protein TetR; SPTR: Transcriptional regulator; PFAM: Bacterial regulatory proteins, tetR family YP_004162226.1 COGs: COG2189 Adenine specific DNA methylase Mod; InterPro IPR002052: IPR002941: IPR001091; KEGG: gwc:GWCH70_2068 DNA methylase N-4/N-6 domain protein; PFAM: DNA methylase N-4/N-6 domain protein; PRIAM: Site-specific DNA-methyltransferase (adenine-specific); SPTR: uncharacterized protein; PFAM: DNA methylase YP_004162227.1 KEGG: gwc:GWCH70_2067 type III restriction protein res subunit; SPTR: uncharacterized protein; PFAM: type III restriction enzyme, res subunit YP_004162229.1 COGs: COG3345 alpha-galactosidase; InterPro IPR002252: IPR000111; KEGG: pdi:BDI_0447 alpha-glycosidase; PFAM: glycoside hydrolase clan GH-D; PRIAM: alpha-galactosidase; SPTR: uncharacterized protein; PFAM: Melibiase YP_004162230.1 COGs: COG3842 ABC-type spermidine/putrescine transport systems ATPase components; InterProIPR017871: IPR003593: IPR003439: IPR017879: IPR 013611; KEGG: pdi:BDI_1648 spermidine/putrescine transport ATP-binding protein; PFAM: ABC transporter related; Transport-associated OB domain-containing protein; SMART: AAA ATPase; SPTR: uncharacterized protein; PFAM: ABC transporter; TOBE domain; TIGRFAM: spermidine/putrescine ABC transporter ATP-binding subunit YP_004162231.1 COGs: COG1176 ABC-type spermidine/putrescine transport system permease component I; InterPro IPR000515; KEGG: pdi:BDI_1647 putrescine transport system permease PotH; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: uncharacterized protein; PFAM: Binding-protein-dependent transport system inner membrane component YP_004162232.1 COGs: COG1177 ABC-type spermidine/putrescine transport system permease component II; InterPro IPR000515; KEGG: pdi:BDI_1646 putrescine transport system permease PotI; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: uncharacterized protein; PFAM: Binding-protein-dependent transport system inner membrane component YP_004162233.1 COGs: COG0687 Spermidine/putrescine-binding periplasmic protein; InterPro IPR001188; KEGG: pdi:BDI_1645 spermidine/putrescine ABC transporter; SPTR: uncharacterized protein; PFAM: Bacterial extracellular solute-binding protein YP_004162234.1 COGs: COG1820 N-acetylglucosamine-6-phosphate deacetylase; InterPro IPR003764: IPR006680; KEGG: bfs:BF2752 N-acetylglucosamine-6-phosphate deacetylase; PFAM: amidohydrolase; PRIAM: N-acetylglucosamine-6-phosphate deacetylase; SPTR: uncharacterized protein; TIGRFAM: N-acetylglucosamine-6-phosphate deacetylase; PFAM: Amidohydrolase; TIGRFAM: N-acetylglucosamine-6-phosphate deacetylase YP_004162235.1 COGs: COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)protein; InterPro IPR006665: IPR006664; KEGG: bfs:BF1959 OmpA family membrane protein; PFAM: OmpA/MotB domain protein; SPTR: uncharacterized protein; PFAM: OmpA family YP_004162236.1 COGs: COG0744 Membrane carboxypeptidase (penicillin-binding protein); InterPro IPR011812: IPR001264; KEGG: bth:BT_1195 monofunctional biosynthetic peptidoglycan transglycosylase; PFAM: glycosyl transferase 51; SPTR: uncharacterized protein; TIGRFAM: monofunctional biosynthetic peptidoglycan transglycosylase; PFAM: Transglycosylase; TIGRFAM: monofunctional biosynthetic peptidoglycan transglycosylase YP_004162237.1 COGs: COG1294 Cytochrome bd-type quinol oxidase subunit 2; InterPro IPR003317; KEGG: bfs:BF1938 cytochrome d ubiquinol oxidase subunit II; PFAM: cytochrome bd ubiquinol oxidase subunit II; SPTR: uncharacterized protein; PFAM: Cytochrome oxidase subunit II; TIGRFAM: cytochrome d oxidase, subunit II (cydB) YP_004162238.1 COGs: COG1271 Cytochrome bd-type quinol oxidase subunit 1; InterPro IPR002585; KEGG: bth:BT_1210 cytochrome d ubiquinol oxidase subunit I; PFAM: cytochrome bd ubiquinol oxidase subunit I; SPTR: uncharacterized protein; PFAM: Bacterial Cytochrome Ubiquinol Oxidase YP_004162239.1 KEGG: bfr:BF1874 hypothetical protein; SPTR: uncharacterized protein YP_004162241.1 COGs: COG1538 Outer membrane protein; InterPro IPR003423; KEGG: bfs:BF1936 outer membrane lipoprotein precursor; PFAM: outer membrane efflux protein; SPTR: uncharacterized protein; PFAM: Outer membrane efflux protein; TIGRFAM: type I secretion outer membrane protein, TolC family YP_004162242.1 COGs: COG0845 Membrane-fusion protein; InterPro IPR006143; KEGG: bfs:BF1935 HlyD family secretion protein; PFAM: hemolysin D; SPTR: uncharacterized protein; TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: HlyD family secretion protein; TIGRFAM: RND family efflux transporter, MFP subunit YP_004162243.1 COGs: COG1136 ABC-type antimicrobial peptide transport system ATPase component; InterPro IPR017871: IPR003593: IPR003439; KEGG: bfs:BF1934 ABC transporter ATP-binding component; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC transporter ATP-binding protein; PFAM: ABC transporter YP_004162244.1 COGs: COG0577 ABC-type antimicrobial peptide transport system permease component; InterPro IPR003838; KEGG: bfs:BF1933 permease component of ABC transporter; PFAM: protein of unknown function DUF214; SPTR: ABC transporter permease; PFAM: Predicted permease YP_004162245.1 COGs: COG3275 regulator of cell autolysis; InterPro IPR010559; KEGG: bth:BT_1216 two-component system sensor; PFAM: histidine kinase internal region; SPTR: uncharacterized protein; PFAM: Histidine kinase YP_004162246.1 COGs: COG3279 Response regulator of the LytR/AlgR family; InterPro IPR001789: IPR007492; KEGG: bfs:BF1931 two-component system response regulator; PFAM: LytTr DNA-binding region; response regulator receiver; SMART: response regulator receiver; SPTR: uncharacterized protein; PFAM: Response regulator receiver domain; LytTr DNA-binding domain YP_004162247.1 InterPro IPR001869; KEGG: sss:SSUSC84_1264 suilysin (hemolysin); PFAM: Thiol-activated cytolysin; SPTR: Hemolysin; PFAM: Thiol-activated cytolysin YP_004162248.1 KEGG: hau:Haur_3530 hypothetical protein; SPTR: Protein-glutaminase YP_004162249.1 COGs: COG0363 6-phosphogluconolactonase/glucosamine-6-phosphate isomerase/deaminase; InterPro IPR005900; KEGG: bfs:BF1921 6-phosphogluconolactonase; SPTR: uncharacterized protein; TIGRFAM: 6-phosphogluconolactonase; TIGRFAM: 6-phosphogluconolactonase YP_004162250.1 COGs: COG0364 glucose-6-phosphate 1-dehydrogenase; InterPro IPR019796: IPR001282; KEGG: bfs:BF1920 glucose-6-phosphate 1-dehydrogenase; PFAM: glucose-6-phosphate dehydrogenase; PRIAM: glucose-6-phosphate dehydrogenase; SPTR: glucose-6-phosphate 1-dehydrogenase; TIGRFAM: glucose-6-phosphate 1-dehydrogenase; PFAM: glucose-6-phosphate dehydrogenase, C-terminal domain; glucose-6-phosphate dehydrogenase, NAD binding domain; TIGRFAM: glucose-6-phosphate 1-dehydrogenase YP_004162251.1 COGs: COG0362 6-phosphogluconate dehydrogenase; InterProIPR006184: IPR006113: IPR006115: IPR006114: IPR 006183; KEGG: bth:BT_1222 6-phosphogluconate dehydrogenase; PFAM: 6-phosphogluconate dehydrogenase domain-containing protein; 6-phosphogluconate dehydrogenase NAD-binding; PRIAM: phosphogluconate dehydrogenase (decarboxylating); SPTR: 6-phosphogluconate dehydrogenase, decarboxylating; TIGRFAM: 6-phosphogluconate dehydrogenase, decarboxylating; PFAM: 6-phosphogluconate dehydrogenase, C-terminal domain; NAD binding domain of 6-phosphogluconate dehydrogenase; TIGRFAM: 6-phosphogluconate dehydrogenase, decarboxylating YP_004162252.1 COGs: COG1301 Na+/H+-dicarboxylate symporter; InterPro IPR001991; KEGG: bfs:BF1918 transmembrane symporter; PFAM: sodium:dicarboxylate symporter; SPTR: Na+/H+-dicarboxylate symporter; PFAM: Sodium:dicarboxylate symporter family YP_004162253.1 KEGG: mag:amb3279 hypothetical protein YP_004162254.1 KEGG: pru:PRU_2116 hypothetical protein; SPTR: uncharacterized protein YP_004162255.1 KEGG: fgr:FG03188.1 hypothetical protein; SPTR: uncharacterized protein YP_004162256.1 KEGG: tet:TTHERM_00697580 hypothetical protein; SPTR: uncharacterized protein YP_004162257.1 InterPro IPR005902; KEGG: pdi:BDI_1003 hypothetical protein; SPTR: uncharacterized protein; TIGRFAM: DNA-binding protein; TIGRFAM: DNA-binding protein, histone-like YP_004162258.1 COGs: COG1089 GDP-D-mannose dehydratase; InterPro IPR020904: IPR006368: IPR001509; KEGG: bvu:BVU_2652 GDP-mannose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; SPTR: uncharacterized protein; TIGRFAM: GDP-mannose 4,6-dehydratase; PFAM: NAD dependent epimerase/dehydratase; TIGRFAM: GDP-mannose 4,6-dehydratase YP_004162259.1 COGs: COG0451 Nucleoside-diphosphate-sugar epimerase; InterPro IPR001509; KEGG: bth:BT_1225 GDP-fucose synthetase; PFAM: NAD-dependent epimerase/dehydratase; PRIAM: GDP-L-fucose synthase; SPTR: uncharacterized protein; PFAM: NAD dependent epimerase/dehydratase YP_004162260.1 COGs: COG1022 Long-chain acyl-CoA synthetase (AMP-forming); InterPro IPR020845: IPR000873; KEGG: bth:BT_1226 long-chain-fatty-acid--CoA ligase; PFAM: AMP-dependent synthetase and ligase; SPTR: uncharacterized protein; PFAM: AMP-binding enzyme YP_004162261.1 InterPro IPR000408: IPR000169; KEGG: bfr:BF1820 hypothetical protein; SPTR: uncharacterized protein YP_004162262.1 COGs: COG3855 conserved hypothetical protein; InterPro IPR009164; KEGG: bfs:BF1884 hypothetical protein; PFAM: fructose-16-bisphosphatase; PRIAM: Fructose-bisphosphatase; SPTR: Fructose-1,6-bisphosphatase class 3; PFAM: Firmicute fructose-1,6-bisphosphatase YP_004162263.1 COGs: COG2985 permease; InterPro IPR006037: IPR006512; KEGG: bfr:BF1818 hypothetical protein; PFAM: YidE/YbjL duplication domain-containing protein; TrkA-C domain protein; SPTR: uncharacterized protein; TIGRFAM: YidE/YbjL duplication; PFAM: Predicted Permease Membrane Region; TrkA-C domain; TIGRFAM: AspT/YidE/YbjL antiporter duplication domain YP_004162264.1 COGs: COG0306 phosphate/sulphate permease; InterPro IPR001204; KEGG: bvu:BVU_2706 inorganic phosphate transporter; PFAM: phosphate transporter; SPTR: uncharacterized protein; PFAM: phosphate transporter family YP_004162265.1 COGs: COG1392 phosphate transport regulator (distant homolog of PhoU); InterPro IPR018445; KEGG: bth:BT_4638 hypothetical protein; PFAM: Putitive phosphate transport regulator; SPTR: uncharacterized protein; PFAM: Protein of unknown function DUF47; TIGRFAM: conserved hypothetical protein TIGR00153 YP_004162266.1 COGs: COG0586 membrane-associated protein; InterPro IPR015414; KEGG: bvu:BVU_2704 hypothetical protein; PFAM: SNARE associated Golgi protein; SPTR: uncharacterized protein; PFAM: SNARE associated Golgi protein YP_004162267.1 KEGG: bth:BT_4640 hypothetical protein; SPTR: uncharacterized protein YP_004162268.1 KEGG: bfs:BF3328 lipoprotein; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF1812) YP_004162269.1 KEGG: bfs:BF1978 hypothetical protein; SPTR: uncharacterized protein; TIGRFAM: Fibrobacter succinogenes major paralogous domain YP_004162270.1 COGs: COG0534 Na+-driven multidrug efflux pump; InterPro IPR002528; KEGG: bfr:BF1817 Na+ driven multidrug efflux pump; PFAM: multi antimicrobial extrusion protein MatE; SPTR: uncharacterized protein; TIGRFAM: MATE efflux family protein; PFAM: MatE; TIGRFAM: efflux protein, MATE family YP_004162271.1 COGs: COG0318 Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterPro IPR020845: IPR000873; KEGG: bvu:BVU_2415 O-succinylbenzoate--CoA ligase; PFAM: AMP-dependent synthetase and ligase; SPTR: uncharacterized protein; PFAM: AMP-binding enzyme YP_004162272.1 COGs: COG4948 L-alanine-DL-glutamate epimerase; InterPro IPR018110: IPR013342; KEGG: bvu:BVU_2416 muconate cycloisomerase; PFAM: Mandelate racemase/muconate lactonizing protein; SPTR: muconate cycloisomerase; PFAM: Mandelate racemase / muconate lactonizing enzyme, C-terminal domain; TIGRFAM: o-succinylbenzoic acid (OSB) synthetase YP_004162273.1 COGs: COG0447 Dihydroxynaphthoic acid synthase; InterPro IPR018376: IPR010198: IPR001753; KEGG: bvu:BVU_2417 naphthoate synthase; PFAM: Enoyl-CoA hydratase/isomerase; SPTR: Naphthoate synthase; TIGRFAM: naphthoate synthase; PFAM: Enoyl-CoA hydratase/isomerase; TIGRFAM: naphthoate synthase (dihydroxynaphthoic acid synthetase) YP_004162274.1 COGs: COG1165 2-succinyl-6-hydroxy-2 4-cyclohexadiene-1-carboxylate synthase; InterPro IPR004433: IPR012001; KEGG: bvu:BVU_2418 2-oxoglutarate decarboxylase; PFAM: thiamine pyrophosphate TPP-binding domain-containing protein; SPTR:2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexe ne-1-carboxylatesynthase; TIGRFAM: 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid synthase/2-oxoglutarate decarboxylase; PFAM: Thiamine pyrophosphate enzyme, N-terminal TPP binding domain; TIGRFAM: 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1- carboxylic-acid synthase YP_004162275.1 COGs: COG1169 Isochorismate synthase; InterPro IPR004561: IPR015890; KEGG: bvu:BVU_2419 isochorismate synthase EntC; PFAM: Chorismate binding-like; SPTR: Isochorismate synthase EntC; TIGRFAM: isochorismate synthase; PFAM: chorismate binding enzyme; TIGRFAM: isochorismate synthases YP_004162276.1 KEGG: ecr:ECIAI1_3816 DNA-damage-inducible protein D; SPTR: DNA-damage-inducible protein D YP_004162277.1 KEGG: tet:TTHERM_00951730 ABC transporter family protein; SPTR: ABC transporter family protein YP_004162278.1 KEGG: bfr:BF1286 hypothetical protein; SPTR: uncharacterized protein YP_004162279.1 KEGG: bfr:BF1950 hypothetical protein; SPTR: uncharacterized protein YP_004162281.1 KEGG: phe:Phep_1494 hypothetical protein; SPTR: uncharacterized protein YP_004162282.1 KEGG: sgo:SGO_1603 hypothetical protein; SPTR: Predicted protein; PFAM: Interferon-induced transmembrane protein YP_004162283.1 KEGG: chu:CHU_1410 hypothetical protein; SPTR: uncharacterized protein YP_004162284.1 KEGG: phe:Phep_1494 hypothetical protein; SPTR: uncharacterized protein YP_004162285.1 COGs: COG2849 conserved hypothetical protein; InterPro IPR011652; KEGG: bth:BT_1755 hypothetical protein; SPTR: uncharacterized protein; PFAM: MORN repeat variant YP_004162286.1 InterPro IPR001647; KEGG: bfr:BF2828 transcriptional regulator; PFAM: regulatory protein TetR; SPTR: uncharacterized protein; PFAM: Bacterial regulatory proteins, tetR family YP_004162287.1 InterPro IPR000595; KEGG: bfs:BF1878 DNA-binding cyclic-nucleotide binding protein; PFAM: cyclic nucleotide-binding; SPTR: uncharacterized protein; PFAM: Cyclic nucleotide-binding domain YP_004162288.1 COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR018060: IPR000005: IPR020449; KEGG: pdi:BDI_0788 transcriptional regulator; PFAM: helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: uncharacterized protein; PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family YP_004162289.1 COGs: COG4771 Outer membrane receptor for ferrienterochelin and colicins; InterPro IPR012910: IPR000531; KEGG: bfr:BF1811 TonB-dependent outer membrane receptor; PFAM: TonB-dependent receptor plug; TonB-dependent receptor; SPTR: uncharacterized protein; PFAM: TonB dependent receptor; TonB-dependent Receptor Plug Domain YP_004162290.1 KEGG: bfr:BF1810 hypothetical protein; SPTR: uncharacterized protein YP_004162291.1 COGs: COG0737 5'-nucleotidase/2' 3'-cyclic phosphodiesterase and related esterase; InterPro IPR004843: IPR008334: IPR006179; KEGG: bfs:BF1873 2', 3'-cyclic nucleotide 2'-phosphodiesterase; PFAM: 5'-Nucleotidase domain-containing protein; metallophosphoesterase; SPTR: uncharacterized protein; PFAM: 5'-nucleotidase, C-terminal domain; Calcineurin-like phosphoesterase YP_004162292.1 COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661: IPR003594: IPR005467: IPR004358; KEGG: bfr:BF1807 two-component system sensor histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: uncharacterized protein; manually curated; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain YP_004162293.1 COGs: COG2183 Transcriptional accessory protein; InterPro IPR006641: IPR003029: IPR018974; KEGG: bth:BT_1238 RNA-binding protein; PFAM: Tex-like protein-like; RNA binding S1 domain protein; SMART: Resolvase RNase H domain protein fold; SPTR: uncharacterized protein; PFAM: Tex-like protein N-terminal domain; S1 RNA binding domain; TIGRFAM: competence protein ComEA helix-hairpin-helix repeat region YP_004162294.1 InterPro IPR003675; KEGG: bth:BT_1239 metal-dependent membrane protease; PFAM: Abortive infection protein; SPTR: uncharacterized protein; PFAM: CAAX amino terminal protease YP_004162295.1 KEGG: bth:BT_1240 hypothetical protein; SPTR: uncharacterized protein YP_004162296.1 COGs: COG0488 ATPase components of ABC transporter with duplicated ATPase domains; InterPro IPR003593: IPR003439; KEGG: bth:BT_1242 ABC transporter ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: uncharacterized protein; PFAM: ABC transporter YP_004162297.1 COGs: COG1629 Outer membrane receptor protein mostly Fe transport; InterPro IPR012910: IPR000531; KEGG: bfs:BF1986 outer membrane protein; PFAM: TonB-dependent receptor plug; TonB-dependent receptor; SPTR: outer membrane protein; PFAM: TonB dependent receptor; TonB-dependent Receptor Plug Domain YP_004162298.1 InterPro IPR011701; KEGG: bfs:BF1985 transmembrane transporter protein; PFAM: major facilitator superfamily MFS_1; SPTR: transmembrane transporter protein; PFAM: Major Facilitator Superfamily YP_004162299.1 COGs: COG0635 Coproporphyrinogen III oxidase and related Fe-S oxidoreductase; InterPro IPR006638: IPR004558: IPR007197: IPR010723; KEGG: bfr:BF1914 coproporphyrinogen III oxidase; PFAM: radical SAM protein; HemN domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: oxygen-independent coproporphyrinogen III oxidase; TIGRFAM: oxygen-independent coproporphyrinogen III oxidase; PFAM: Radical SAM superfamily; HemN C-terminal region; TIGRFAM: oxygen-independent coproporphyrinogen III oxidase YP_004162300.1 COGs: COG1232 Protoporphyrinogen oxidase; InterPro IPR004572: IPR002937; KEGG: bfr:BF1913 protoporphyrinogen oxidase; PFAM: amine oxidase; SPTR: Protoporphyrinogen oxidase; TIGRFAM: protoporphyrinogen oxidase; PFAM: Flavin containing amine oxidoreductase; TIGRFAM: protoporphyrinogen oxidase YP_004162301.1 COGs: COG1587 Uroporphyrinogen-III synthase; KEGG: lif:LinJ03.0300 hypothetical protein; SPTR: uncharacterized protein; PFAM: Uroporphyrinogen-III synthase HemD YP_004162302.1 COGs: COG0576 Molecular chaperone GrpE (heat shock protein); InterPro IPR000740; KEGG: bth:BT_1243 GrpE protein (HSP-70 cofactor); PFAM: GrpE protein; SPTR: uncharacterized protein; PFAM: GrpE YP_004162303.1 COGs: COG0484 DnaJ-class molecular chaperone with C-terminal Zn finger domain; InterProIPR018253: IPR001623: IPR001305: IPR012724: IPR 002939: IPR003095; KEGG: bfs:BF1818 chaperone protein DnaJ; PFAM: chaperone DnaJ domain protein; heat shock protein DnaJ domain protein; DnaJ central domain protein; SMART: heat shock protein DnaJ domain protein; SPTR: Chaperone protein dnaJ; TIGRFAM: chaperone protein DnaJ; PFAM: DnaJ C terminal region; DnaJ domain; DnaJ central domain (4 repeats); TIGRFAM: chaperone protein DnaJ YP_004162304.1 KEGG: bfs:BF4290 hypothetical protein; SPTR: uncharacterized protein YP_004162305.1 KEGG: bfs:BF4295 hypothetical protein; SPTR: uncharacterized protein YP_004162306.1 KEGG: bfs:BF4296 hypothetical protein; SPTR: uncharacterized protein YP_004162307.1 KEGG: dfe:Dfer_3749 hypothetical protein; SPTR: uncharacterized protein YP_004162308.1 KEGG: pdi:BDI_2952 hypothetical protein; SPTR: uncharacterized protein YP_004162309.1 COGs: COG3055 conserved hypothetical protein; InterPro IPR019937: IPR001087: IPR005181: IPR006652; KEGG: bfs:BF1809 sialate O-acetylesterase; PFAM: protein of unknown function DUF303 acetylesterase; lipolytic protein G-D-S-L family; Kelch repeat type 1-containing protein; PRIAM: Sialate O-acetylesterase; SPTR: Sialate O-acetylesterase; TIGRFAM: cyclically-permuted mutatrotase; PFAM: Domain of unknown function (DUF303); GDSL-like Lipase/Acylhydrolase; TIGRFAM: cyclically-permuted mutatrotase YP_004162310.1 KEGG: bfr:BF2190 acetylhydrolase; SPTR: uncharacterized protein YP_004162311.1 COGs: COG3525 N-acetyl-beta-hexosaminidase; InterPro IPR015883: IPR001540; KEGG: bfr:BF1730 beta-N-acetylhexosaminidase; PFAM: glycoside hydrolase 20; SPTR: Beta-N-acetylhexosaminidase; PFAM: glycosyl hydrolase 20, catalytic domain; glycosyl hydrolase 20, domain 2 YP_004162312.1 KEGG: bmy:Bm1_09230 S-adenosylmethionine synthetase; SPTR: Zeta toxin YP_004162313.1 COGs: COG4409 Neuraminidase (sialidase); KEGG: bvu:BVU_4143 sialidase; SPTR: Sialidase; PFAM: BNR/Asp-box repeat YP_004162314.1 KEGG: bfr:BF1715 hypothetical protein; SPTR: uncharacterized protein YP_004162315.1 InterPro IPR012944; KEGG: bfs:BF1721 hypothetical protein; PFAM: RagB/SusD domain protein; SPTR: uncharacterized protein; PFAM: SusD family YP_004162316.1 InterPro IPR018247: IPR001917: IPR012910: IPR000531; KEGG: bfr:BF1722 hypothetical protein; PFAM: TonB-dependent receptor plug; TonB-dependent receptor; SPTR: outer membrane protein probably involved in nutrient binding; PFAM: TonB-dependent Receptor Plug Domain; TonB dependent receptor YP_004162317.1 COGs: COG2942 N-acyl-D-glucosamine 2-epimerase; InterPro IPR010819; KEGG: bvu:BVU_4118 renin-binding protein-related protein; PFAM: N-acylglucosamine 2-epimerase; PRIAM: N-acylglucosamine 2-epimerase; SPTR: uncharacterized protein; PFAM: N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) YP_004162318.1 COGs: COG0329 Dihydrodipicolinate synthase/N-acetylneuraminate lyase; InterPro IPR002220; KEGG: bvu:BVU_4117 N-acetylneuraminate lyase; PFAM: dihydrodipicolinate synthetase; PRIAM: N-acetylneuraminate lyase; SPTR: uncharacterized protein; PFAM: Dihydrodipicolinate synthetase YP_004162319.1 COGs: COG2271 Sugar phosphate permease; InterPro IPR011701: IPR005829; KEGG: bfs:BF1714 major facilitator transporter; PFAM: major facilitator superfamily MFS_1; SPTR: uncharacterized protein; PFAM: Major Facilitator Superfamily YP_004162320.1 COGs: COG2731 Beta-galactosidase beta subunit; InterPro IPR004375; KEGG: bfr:BF1709 hypothetical protein; PFAM: Conserved hypothetical protein CHP00022; SPTR: uncharacterized protein; PFAM: Domain of unknown function (DUF386); TIGRFAM: uncharacterized protein, YhcH/YjgK/YiaL family YP_004162321.1 COGs: COG3250 Beta-galactosidase/beta-glucuronidase; InterPro IPR006104; KEGG: bfr:BF1733 beta-mannosidase; PFAM: glycoside hydrolase 2 sugar binding; PRIAM: Beta-mannosidase; SPTR: Beta-mannosidase; PFAM: domain; glycosyl hydrolases family 2, TIM barrel domain; glycosyl hydrolases family 2, sugar binding domain YP_004162322.1 COGs: COG3525 N-acetyl-beta-hexosaminidase; InterPro IPR015882: IPR015883: IPR000421: IPR001540; KEGG: bfr:BF1734 beta-N-acetylhexosaminidase; PFAM: glycoside hydrolase 20; Beta-N-acetylhexosaminidase, subunit a/b; coagulation factor 5/8 type domain protein; PRIAM: Beta-N-acetylhexosaminidase; SPTR: Beta-N-acetylhexosaminidase; PFAM: F5/8 type C domain; glycosyl hydrolase 20, catalytic domain; glycosyl hydrolase 20, domain 2 YP_004162323.1 COGs: COG3525 N-acetyl-beta-hexosaminidase; InterPro IPR015883: IPR001540; KEGG: bfr:BF1736 beta-N-acetylhexosaminidase; PFAM: glycoside hydrolase 20; PRIAM: Beta-N-acetylhexosaminidase; SPTR: Beta-N-acetylhexosaminidase; PFAM: glycosyl hydrolase 20, catalytic domain; glycosyl hydrolase 20, domain 2 YP_004162324.1 COGs: COG3250 Beta-galactosidase/beta-glucuronidase; InterProIPR006104: IPR006102: IPR006103: IPR017972: IPR 006101; KEGG: bfr:BF1738 beta-galactosidase; PFAM: glycoside hydrolase 2 sugar binding; glycoside hydrolase 2 immunoglobulin domain protein beta-sandwich; glycoside hydrolase 2; SPTR: uncharacterized protein; PFAM: domain; glycosyl hydrolases family 2, TIM barrel domain; glycosyl hydrolases family 2, sugar binding domain YP_004162325.1 COGs: COG1940 Transcriptional regulator/sugar kinase; InterPro IPR000600; KEGG: bth:BT_0433 xylose repressor; PFAM: ROK family protein; SPTR: uncharacterized protein; PFAM: ROK family YP_004162326.1 KEGG: bfr:BF1704 hypothetical protein; SPTR: uncharacterized protein; PFAM: Cupin domain YP_004162327.1 InterPro IPR006645; KEGG: bfs:BF1709 LPS-related regulatory protein; PFAM: NGN domain-containing protein; SPTR: uncharacterized protein; PFAM: Transcription termination factor nusG YP_004162328.1 InterPro IPR003856; KEGG: bfr:BF1702 protein involved in capsular polysaccharide biosynthesis; PFAM: lipopolysaccharide biosynthesis protein; SPTR: uncharacterized protein; PFAM: Chain length determinant protein YP_004162329.1 COGs: COG1596 Periplasmic protein involved in polysaccharide export; InterPro IPR003715: IPR019554; KEGG: bfs:BF1707 capsule polysaccharide export protein; PFAM: polysaccharide export protein; Soluble ligand binding domain; SPTR: uncharacterized protein; PFAM: polysaccharide biosynthesis/export protein; SLBB domain YP_004162330.1 COGs: COG1086 nucleoside-diphosphate sugar epimerase; InterPro IPR003869; KEGG: bfs:BF1706 capsular biosynthesis protein; PFAM: polysaccharide biosynthesis protein CapD; SPTR: Capsular polysaccharide biosynthesis protein CapD; PFAM: polysaccharide biosynthesis protein YP_004162331.1 KEGG: bfr:BF2439 hypothetical protein; SPTR: uncharacterized protein YP_004162332.1 KEGG: bfr:BF2440 hypothetical protein; SPTR: uncharacterized protein YP_004162334.1 KEGG: bfr:BF1625 hypothetical protein; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF2874) YP_004162335.1 KEGG: tgo:TGME49_018560 acetyl-coA carboxylase; SPTR: Predicted protein YP_004162336.1 KEGG: bfs:BF2285 hypothetical protein; SPTR: uncharacterized protein YP_004162337.1 KEGG: tra:Trad_0913 nucleoside recognition domain protein; SPTR: Predicted protein YP_004162338.1 KEGG: msu:MS0176 protoporphyrinogen oxidase; SPTR: FldA protein YP_004162339.1 KEGG: aga:AgaP_AGAP002830 AGAP002830-PA; SPTR: uncharacterized protein YP_004162340.1 KEGG: pdi:BDI_0883 hypothetical protein; SPTR: uncharacterized protein YP_004162341.1 COGs: COG5499 transcription regulator containing HTH domain; InterPro IPR001387; KEGG: pdi:BDI_0882 hypothetical protein; PFAM: hypothetical protein; SMART: hypothetical protein; SPTR: uncharacterized protein; PFAM: Helix-turn-helix YP_004162342.1 KEGG: pdi:BDI_0880 hypothetical protein; SPTR: uncharacterized protein; PFAM: Phage portal protein, SPP1 Gp6-like; TIGRFAM: phage portal protein, SPP1 family YP_004162344.1 KEGG: ctp:CTRG_02230 chromatin remodelling complex ATPase chain ISW1; SPTR: adhesin MAA1 YP_004162345.1 InterPro IPR001387: IPR020537; KEGG: bfs:BF0462 regulatory protein; PFAM: hypothetical protein; SMART: hypothetical protein; SPTR: Predicted protein; PFAM: Helix-turn-helix YP_004162346.1 InterPro IPR009241; KEGG: bfr:BF2944 hypothetical protein; PFAM: protein of unknown function DUF891; SPTR: Toxin-antitoxin system, toxin component, RelE family; PFAM: Phage derived protein Gp49-like (DUF891) YP_004162347.1 InterPro IPR001387; KEGG: bfr:BF2945 hypothetical protein; PFAM: hypothetical protein; SMART: hypothetical protein; SPTR: uncharacterized protein; PFAM: Helix-turn-helix YP_004162348.1 KEGG: ptr:742975 heat shock 70kDa protein 4-like; SPTR: cDNA FLJ55529, highly similar to Heat shock 70 kDa protein 4L YP_004162349.1 KEGG: pdi:BDI_0869 hypothetical protein; SPTR: uncharacterized protein YP_004162350.1 SPTR: ZPAX protein YP_004162351.1 COGs: COG1559 periplasmic solute-binding protein; InterPro IPR003770; KEGG: bth:BT_0431 hypothetical protein; PFAM: aminodeoxychorismate lyase; SPTR: uncharacterized protein; PFAM: YceG-like family; TIGRFAM: conserved hypothetical protein, YceG family YP_004162352.1 COGs: COG4231 Indolepyruvate ferredoxin oxidoreductase alpha and beta subunits; InterPro IPR011766: IPR006118; KEGG: bfs:BF1702 indolepyruvate oxidoreductase/indolepyruvate ferredoxin oxidoreductase; PFAM: thiamine pyrophosphate TPP-binding domain-containing protein; SPTR: uncharacterized protein; PFAM: domain; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; TIGRFAM: indolepyruvate ferredoxin oxidoreductase, alpha subunit YP_004162353.1 COGs: COG1014 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase gamma subunit; InterPro IPR019752; KEGG: bfs:BF1701 indolepyruvate oxidoreductase subunit beta; PFAM: Pyruvate/ketoisovalerate oxidoreductase, catalytic domain; SPTR: uncharacterized protein; PFAM: Pyruvate ferredoxin/flavodoxin oxidoreductase; TIGRFAM: indolepyruvate ferredoxin oxidoreductase, beta subunit YP_004162354.1 COGs: COG1541 Coenzyme F390 synthetase; InterPro IPR000873; KEGG: bfs:BF1700 phenylacetate-coenzyme A ligase; PFAM: AMP-dependent synthetase and ligase; PRIAM: Phenylacetate--CoA ligase; SPTR: uncharacterized protein; PFAM: AMP-binding enzyme YP_004162355.1 COGs: COG0292 Ribosomal protein L20; InterPro IPR005813; KEGG: bth:BT_0425 50S ribosomal protein L20; PFAM: ribosomal protein L20; SPTR: 50S ribosomal protein L20; TIGRFAM: ribosomal protein L20; PFAM: Ribosomal protein L20; TIGRFAM: ribosomal protein L20 YP_004162356.1 InterPro IPR001706: IPR021137: IPR018265; KEGG: bth:BT_0424 50S ribosomal protein L35; PFAM: Ribosomal protein L35; SPTR: 50S ribosomal protein L35; TIGRFAM: ribosomal protein L35; PFAM: Ribosomal protein L35; TIGRFAM: ribosomal protein L35 YP_004162357.1 COGs: COG0290 Translation initiation factor 3 (IF-3); InterPro IPR001288: IPR019814: IPR019815: IPR019813; KEGG: bfs:BF1695 translation initiation factor IF-3; PFAM: Translation initiation factor 3-like; SPTR: Translation initiation factor IF-3; TIGRFAM: translation initiation factor IF-3; manually curated; PFAM: Translation initiation factor IF-3, C-terminal domain; Translation initiation factor IF-3, N-terminal domain; TIGRFAM: translation initiation factor IF-3 YP_004162358.1 COGs: COG0441 Threonyl-tRNA synthetase; InterProIPR002320: IPR004095: IPR012947: IPR002314: IPR 004154: IPR006195: IPR018158; KEGG: bfs:BF1694 threonyl-tRNA synthetase; PFAM: tRNA synthetase class II (G H P and S); threonyl/alanyl tRNA synthetase; TGS domain-containing protein; Anticodon-binding domain protein; SPTR: Threonyl-tRNA synthetase; TIGRFAM: threonyl-tRNA synthetase; PFAM: Anticodon binding domain; Threonyl and Alanyl tRNA synthetase second additional domain; tRNA synthetase class II core domain (G, H, P, S and T); TGS domain; TIGRFAM: threonyl-tRNA synthetase YP_004162359.1 InterPro IPR019734: IPR001440: IPR013026; KEGG: bfs:BF1693 TPR repeat-containing protein; PFAM: hypothetical protein; SMART: Tetratricopeptide repeat; SPTR: uncharacterized protein; PFAM: Tetratricopeptide repeat YP_004162360.1 COGs: COG0242 N-formylmethionyl-tRNA deformylase; InterPro IPR000181; KEGG: bfs:BF1691 peptide deformylase; PFAM: formylmethionine deformylase; PRIAM: peptide deformylase; SPTR: peptide deformylase; TIGRFAM: peptide deformylase; PFAM: polypeptide deformylase; TIGRFAM: peptide deformylase YP_004162361.1 COGs: COG0816 endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis); InterPro IPR006641: IPR005227; KEGG: bth:BT_0419 Holliday junction resolvase-like protein; PFAM: Holliday junction resolvase YqgF; SMART: Resolvase RNase H domain protein fold; SPTR: Holliday junction resolvase; PFAM: Uncharacterised protein family (UPF0081); TIGRFAM: RNAse H-fold protein YqgF YP_004162362.1 KEGG: bfs:BF1682 hypothetical protein; SPTR: uncharacterized protein; PFAM: Bacterial lipoprotein (DUF940) YP_004162363.1 COGs: COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)protein; InterPro IPR006665; KEGG: bvu:BVU_4065 major outer membrane protein OmpA; PFAM: OmpA/MotB domain protein; SPTR: uncharacterized protein; PFAM: OmpA family YP_004162364.1 KEGG: bvu:BVU_4064 hypothetical protein; SPTR: uncharacterized protein YP_004162365.1 KEGG: bvu:BVU_4063 hypothetical protein; SPTR: uncharacterized protein; PFAM: Bacterial lipoprotein (DUF940) YP_004162366.1 COGs: COG4974 Site-specific recombinase XerD; InterPro IPR002104; KEGG: bfs:BF1685 bacteriophage integrase; PFAM: integrase; SPTR: uncharacterized protein; PFAM: Phage integrase YP_004162367.1 KEGG: bvu:BVU_4063 hypothetical protein; SPTR: uncharacterized protein; PFAM: Bacterial lipoprotein (DUF940) YP_004162368.1 KEGG: bvu:BVU_4064 hypothetical protein; SPTR: uncharacterized protein YP_004162369.1 COGs: COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)protein; InterPro IPR006665; KEGG: bfs:BF1689 outer membrane protein; PFAM: OmpA/MotB domain protein; SPTR: uncharacterized protein; PFAM: OmpA family YP_004162370.1 KEGG: bfs:BF1682 hypothetical protein; SPTR: uncharacterized protein; PFAM: Bacterial lipoprotein (DUF940) YP_004162371.1 KEGG: bth:BT_0417 hypothetical protein; SPTR: uncharacterized protein YP_004162372.1 KEGG: bfs:BF1678 sulfotransferase; SPTR: uncharacterized protein; PFAM: Sulfotransferase domain YP_004162373.1 COGs: COG2895 GTPase - Sulfate adenylate transferase subunit 1; InterPro IPR005225: IPR011779: IPR000795: IPR004161; KEGG: bth:BT_0415 sulfate adenylyltransferase subunit 1; PFAM: protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; PRIAM: Sulfate adenylyltransferase; SPTR: uncharacterized protein; TIGRFAM: sulfate adenylyltransferase, large subunit; small GTP-binding protein; PFAM: Elongation factor Tu domain 2; Elongation factor Tu GTP binding domain; TIGRFAM: sulfate adenylyltransferase, large subunit; small GTP-binding protein domain YP_004162374.1 COGs: COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase; InterPro IPR011784: IPR002500; KEGG: bfs:BF1676 sulfate adenylyltransferase subunit 2; PFAM: phosphoadenosine phosphosulfate reductase; SPTR: uncharacterized protein; TIGRFAM: sulfate adenylyltransferase, small subunit; PFAM: phosphoadenosine phosphosulfate reductase; TIGRFAM: sulfate adenylyltransferase, small subunit YP_004162375.1 COGs: COG0529 Adenylylsulfate kinase and related kinase; InterPro IPR002891; KEGG: bth:BT_0413 adenylylsulfate kinase; PFAM: adenylylsulfate kinase; PRIAM: Adenylyl-sulfate kinase; SPTR: Adenylyl-sulfate kinase; TIGRFAM: adenylylsulfate kinase; PFAM: Adenylylsulphate kinase; TIGRFAM: adenylylsulfate kinase (apsK) YP_004162376.1 COGs: COG0471 Di- and tricarboxylate transporter; InterPro IPR004680: IPR006037: IPR001898; KEGG: bfs:BF1674 Na+/sulfite symporter; PFAM: TrkA-C domain protein; Citrate transporter; SPTR: uncharacterized protein; PFAM: Citrate transporter YP_004162377.1 COGs: COG1218 3'-phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase; InterPro IPR006240: IPR000760: IPR020583; KEGG: bfs:BF1673 sulfite synthesis pathway protein; PFAM: inositol monophosphatase; SPTR: uncharacterized protein; TIGRFAM: 3'(2'),5'-bisphosphate nucleotidase; PFAM: inositol monophosphatase; TIGRFAM: 3'(2'),5'-bisphosphate nucleotidase, bacterial YP_004162378.1 InterPro IPR007730; KEGG: bfs:BF1670 hypothetical protein; PFAM: Sporulation domain-containing protein; SPTR: uncharacterized protein; PFAM: Sporulation related domain YP_004162379.1 COGs: COG0513 Superfamily II DNA and RNA helicase; InterProIPR014001: IPR001650: IPR011545: IPR000629: IPR 014021: IPR014014; KEGG: bfs:BF1668 ATP-dependent RNA helicase; PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; SPTR: ATP-dependent RNA helicase DeaD; PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase YP_004162381.1 KEGG: bfs:BF1667 hypothetical protein; SPTR: Conserved domain protein YP_004162382.1 KEGG: bth:BT_0407 hypothetical protein; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF1469) YP_004162383.1 KEGG: bth:BT_0406 hypothetical protein; SPTR: uncharacterized protein YP_004162384.1 COGs: COG1482 phosphomannose isomerase; InterPro IPR001250: IPR014628; KEGG: bfs:BF1664 mannose-6-phosphate isomerase; PFAM: mannose-6-phosphate isomerase type I; PRIAM: Mannose-6-phosphate isomerase; SPTR: Mannose-6-phosphate isomerase, class I; TIGRFAM: mannose-6-phosphate isomerase, class I; PFAM: phosphomannose isomerase type I; TIGRFAM: mannose-6-phosphate isomerase, class I YP_004162385.1 COGs: COG2017 Galactose mutarotase; InterPro IPR008183; KEGG: bth:BT_0372 aldose 1-epimerase precursor; PFAM: Aldose 1-epimerase; PRIAM: Aldose 1-epimerase; SPTR: uncharacterized protein; PFAM: Aldose 1-epimerase YP_004162386.1 COGs: COG0738 Fucose permease; InterPro IPR011701; KEGG: bth:BT_0371 glucose/galactose transporter; PFAM: major facilitator superfamily MFS_1; SPTR: uncharacterized protein; PFAM: Major Facilitator Superfamily YP_004162387.1 COGs: COG0153 Galactokinase; InterProIPR000705: IPR019539: IPR006204: IPR013750: IPR 019741: IPR006203: IPR018294: IPR006206; KEGG: bvu:BVU_2325 galactokinase; PFAM: Galactokinase galactose-binding domain; GHMP kinase; GHMP kinase domain protein; SPTR: Galactokinase; TIGRFAM: galactokinase; PFAM: Galactokinase galactose-binding signature; GHMP kinases C terminal; GHMP kinases N terminal domain; TIGRFAM: galactokinase YP_004162388.1 COGs: COG0021 Transketolase; InterPro IPR005474: IPR005475: IPR020826; KEGG: bth:BT_0347 transketolase; PFAM: Transketolase domain-containing protein; Transketolase central region; PRIAM: formaldehyde transketolase; SPTR: uncharacterized protein; PFAM: Transketolase, thiamine diphosphate binding domain; Transketolase, pyrimidine binding domain YP_004162389.1 COGs: COG0698 Ribose 5-phosphate isomerase RpiB; InterPro IPR004785: IPR003500; KEGG: bfr:BF1651 ribose 5-phosphate isomerase B; PFAM: Ribose/galactose isomerase; SPTR: uncharacterized protein; TIGRFAM: sugar-phosphate isomerase, RpiB/LacA/LacB family; ribose 5-phosphate isomerase B; PFAM: Ribose/Galactose Isomerase; TIGRFAM: ribose 5-phosphate isomerase B; sugar-phosphate isomerases, RpiB/LacA/LacB family YP_004162390.1 InterPro IPR019734: IPR001440: IPR013026; KEGG: bfs:BF1658 hypothetical protein; PFAM: hypothetical protein; SMART: Tetratricopeptide repeat; SPTR: uncharacterized protein; PFAM: Tetratricopeptide repeat YP_004162391.1 InterPro IPR017900: IPR017896; KEGG: bfs:BF1657 ferredoxin; SPTR: uncharacterized protein; PFAM: 4Fe-4S binding domain YP_004162392.1 COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterPro IPR002880: IPR005476; KEGG: bfs:BF1656 2-ketoisovalerate ferredoxin reductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Transketolase domain-containing protein; SPTR: uncharacterized protein; PFAM: domain; Transketolase, C-terminal domain YP_004162393.1 KEGG: bfs:BF1655 hypothetical protein; SPTR: uncharacterized protein; manually curated YP_004162394.1 COGs: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase beta subunit; InterPro IPR011766; KEGG: bfs:BF1653 2-oxoglutarate synthase subunit; PFAM: thiamine pyrophosphate TPP-binding domain-containing protein; SPTR: uncharacterized protein; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP binding domain YP_004162395.1 COGs: COG1014 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase gamma subunit; InterPro IPR019752; KEGG: bfs:BF1652A 2-oxoglutarate synthase subunit; PFAM: Pyruvate/ketoisovalerate oxidoreductase, catalytic domain; SPTR: Ketoisovalerate ferredoxin oxidoreductase; PFAM: Pyruvate ferredoxin/flavodoxin oxidoreductase YP_004162396.1 KEGG: bfs:BF1652 hypothetical protein; SPTR: uncharacterized protein YP_004162397.1 COGs: COG0834 ABC-type amino acid transport/signal transduction systems periplasmic component/domain; InterPro IPR001638; KEGG: bth:BT_0327 glutamine ABC transporter, periplasmic glutamine-binding protein (GlnH); PFAM: extracellular solute-binding protein family 3; SMART: extracellular solute-binding protein family 3; SPTR: uncharacterized protein; PFAM: Bacterial extracellular solute-binding proteins, family 3 YP_004162398.1 COGs: COG0171 NAD synthase; InterPro IPR003694: IPR003010: IPR014445; KEGG: bfs:BF3022 NAD synthetase; PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; SPTR: uncharacterized protein; TIGRFAM: NAD+ synthetase; PFAM: NAD synthase; Carbon-nitrogen hydrolase; TIGRFAM: NAD+ synthetase YP_004162399.1 COGs: COG0735 Fe2+/Zn2+ uptake regulation protein; InterPro IPR002481; KEGG: bfr:BF3179 iron uptake regulatory protein; PFAM: ferric-uptake regulator; SPTR: uncharacterized protein; manually curated; PFAM: Ferric uptake regulator family YP_004162400.1 COGs: COG1592 Rubrerythrin; InterPro IPR004039: IPR003251: IPR009040; KEGG: bfs:BF3018 rubrerythrin-like protein; PFAM: Rubrerythrin; Rubredoxin-type Fe(Cys)4 protein; SPTR: rubrerythrin; PFAM: Rubrerythrin YP_004162401.1 COGs: COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog; InterPro IPR014284: IPR007627: IPR013249; KEGG: bth:BT_0326 RNA polymerase ECF-type sigma factor; PFAM: Sigma-70 region 4 type 2; sigma-70 region 2 domain protein; SPTR: uncharacterized protein; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family YP_004162402.1 KEGG: bfs:BF1648 hypothetical protein; SPTR: uncharacterized protein YP_004162403.1 KEGG: bth:BT_0324 hypothetical protein; SPTR: uncharacterized protein YP_004162404.1 KEGG: bth:BT_0323 hypothetical protein; SPTR: uncharacterized protein YP_004162405.1 KEGG: bfs:BF1644 hypothetical protein; SPTR: hemin receptor; PFAM: Outer membrane protein transport protein (OMPP1/FadL/TodX) YP_004162406.1 KEGG: bfs:BF1643 hypothetical protein; SPTR: uncharacterized protein YP_004162407.1 COGs: COG2264 Ribosomal protein L11 methylase; InterPro IPR004498: IPR010456; KEGG: bfs:BF1638 ribosomal protein L11 methyltransferase; PFAM: ribosomal L11 methyltransferase; SPTR: Ribosomal protein L11 methyltransferase; PFAM: Ribosomal protein L11 methyltransferase (PrmA); TIGRFAM: ribosomal protein L11 methyltransferase YP_004162408.1 InterPro IPR003838; KEGG: bfr:BF1501 ABC transporter permease; PFAM: protein of unknown function DUF214; SPTR: ABC transporter permease; PFAM: Predicted permease YP_004162409.1 COGs: COG0577 ABC-type antimicrobial peptide transport system permease component; InterPro IPR003838; KEGG: bfs:BF1433 ABC transporter permease component; PFAM: protein of unknown function DUF214; SPTR: ABC transporter permease component; manually curated; PFAM: Predicted permease YP_004162410.1 COGs: COG3757 Lyzozyme M1 (1 4-beta-N-acetylmuramidase); InterPro IPR018077: IPR002053; KEGG: bfr:BF3098 glycosylhydrolase; PFAM: glycoside hydrolase 25; PRIAM: Lysozyme; SMART: glycoside hydrolase, family 25 subgroup; SPTR: uncharacterized protein; PFAM: glycosyl hydrolases family 25 YP_004162411.1 COGs: COG0205 6-phosphofructokinase; InterPro IPR011183: IPR000023; KEGG: bth:BT_0307 diphosphate--fructose-6-phosphate 1-phosphotransferase; PFAM: phosphofructokinase; SPTR: uncharacterized protein; TIGRFAM: diphosphate/fructose-6-phosphate 1-phosphotransferase; PFAM: phosphofructokinase; TIGRFAM: diphosphate--fructose-6-phosphate 1-phosphotransferase YP_004162413.1 COGs: COG0724 RNA-binding protein (RRM domain); InterPro IPR000504; KEGG: bth:BT_1887 RNA-binding protein RbpA; PFAM: RNP-1 like RNA-binding protein; SMART: RNP-1 like RNA-binding protein; SPTR: uncharacterized protein; PFAM: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) YP_004162414.1 KEGG: bth:BT_0261 hypothetical protein; SPTR: uncharacterized protein YP_004162415.1 COGs: COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase; InterPro IPR002123; KEGG: bth:BT_0260 acyltransferase; PFAM: phospholipid/glycerol acyltransferase; SMART: phospholipid/glycerol acyltransferase; SPTR: uncharacterized protein; PFAM: Acyltransferase YP_004162416.1 COGs: COG0388 amidohydrolase; InterPro IPR003010; KEGG: bth:BT_0259 amidohydrolase; PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; SPTR: uncharacterized protein; PFAM: Carbon-nitrogen hydrolase YP_004162417.1 COGs: COG2859 conserved hypothetical protein; InterPro IPR007497: IPR016907; KEGG: bvu:BVU_2585 hypothetical protein; PFAM: protein of unknown function DUF541; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF541) YP_004162418.1 KEGG: bth:BT_2509 transcriptional regulator; SPTR: uncharacterized protein YP_004162419.1 KEGG: pdi:BDI_1264 hypothetical protein; SPTR: uncharacterized protein; PFAM: OmpA family YP_004162420.1 KEGG: osa:4342280 hypothetical protein; SPTR: uncharacterized protein YP_004162421.1 COGs: COG1820 N-acetylglucosamine-6-phosphate deacetylase; InterPro IPR003764: IPR006680; KEGG: bfs:BF2952 N-acetylglucosamine-6-phosphate deacetylase; PFAM: amidohydrolase; PRIAM: N-acetylglucosamine-6-phosphate deacetylase; SPTR: uncharacterized protein; TIGRFAM: N-acetylglucosamine-6-phosphate deacetylase; PFAM: Amidohydrolase; TIGRFAM: N-acetylglucosamine-6-phosphate deacetylase YP_004162422.1 COGs: COG0363 6-phosphogluconolactonase/glucosamine-6-phosphate isomerase/deaminase; InterPro IPR006148: IPR003737; KEGG: bfs:BF2953 glucosamine-6-phosphate deaminase-like protein; PFAM: LmbE family protein; glucosamine/galactosamine-6-phosphate isomerase; SPTR: uncharacterized protein; PFAM: glucosamine-6-phosphate isomerases/6-phosphogluconolactonase; GlcNAc-PI de-N-acetylase; TIGRFAM: glucosamine-6-phosphate isomerase YP_004162423.1 InterPro IPR003961; KEGG: bfs:BF2955 hypothetical protein; PFAM: Fibronectin type III domain protein; SMART: Fibronectin type III domain protein; SPTR: uncharacterized protein YP_004162424.1 KEGG: bfs:BF2958 hypothetical protein; SPTR: uncharacterized protein YP_004162425.1 KEGG: bth:BT_0255 hypothetical protein; SPTR: uncharacterized protein; PFAM: SirA-like protein YP_004162426.1 COGs: COG1032 Fe-S oxidoreductase; InterPro IPR006638: IPR013704: IPR002052: IPR020612; KEGG: bfs:BF2962 hypothetical protein; PFAM: radical SAM protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: uncharacterized protein; PFAM: Radical SAM superfamily; Radical SAM N-terminal YP_004162427.1 InterPro IPR011496; KEGG: bth:BT_4395 hyaluronoglucosaminidase precursor; PFAM: hyaluronidase; PRIAM: Beta-N-acetylhexosaminidase; SPTR: uncharacterized protein; PFAM: beta-N-acetylglucosaminidase YP_004162428.1 SPTR: uncharacterized protein YP_004162429.1 KEGG: tva:TVAG_014040 hypothetical protein; SPTR: uncharacterized protein YP_004162430.1 KEGG: zro:ZYRO0G02310g hypothetical protein; SPTR: uncharacterized protein YP_004162431.1 COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR018060: IPR000005: IPR020449; KEGG: coc:Coch_1294 AraC family transcriptional regulator; PFAM: helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: AraC family transcriptional regulator; PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family YP_004162432.1 COGs: COG0667 oxidoreductase (related to aryl-alcohol dehydrogenase); InterPro IPR001395; KEGG: bfr:BF2086 aldo/keto reductase; PFAM: aldo/keto reductase; SPTR: uncharacterized protein; PFAM: Aldo/keto reductase YP_004162433.1 KEGG: ect:ECIAI39_2207 outer membrane export usher protein; SPTR: uncharacterized protein YP_004162434.1 KEGG: bvu:BVU_1688 hypothetical protein; SPTR: uncharacterized protein YP_004162435.1 InterPro IPR005902; KEGG: bth:BT_4601 hypothetical protein; SPTR: uncharacterized protein; TIGRFAM: DNA-binding protein; TIGRFAM: DNA-binding protein, histone-like YP_004162436.1 COGs: COG1197 Transcription-repair coupling factor (superfamily II helicase); InterProIPR014001: IPR001650: IPR004576: IPR003711: IPR 011545: IPR005118: IPR018245: IPR014021; KEGG: bth:BT_0252 transcription-repair coupling factor; PFAM: transcription factor CarD; DEAD/DEAH box helicase domain protein; helicase domain protein; TRCF domain protein; SMART: DEAD-like helicase; helicase domain protein; SPTR: uncharacterized protein; TIGRFAM: transcription-repair coupling factor; PFAM: Helicase conserved C-terminal domain; TRCF domain; CarD-like/TRCF domain; DEAD/DEAH box helicase; TIGRFAM: transcription-repair coupling factor (mfd) YP_004162437.1 COGs: COG0463 glycosyltransferase involved in cell wall biogenesis; InterPro IPR001173; KEGG: bth:BT_0251 dolichol-phosphate mannosyltransferase; PFAM: glycosyl transferase 2; SPTR: uncharacterized protein; PFAM: glycosyl transferase 2 YP_004162438.1 COGs: COG0044 Dihydroorotase and related cyclic amidohydrolase; InterPro IPR006680: IPR002195; KEGG: bfs:BF2965 dihydroorotase; PFAM: amidohydrolase; SPTR: Dihydroorotase; PFAM: Amidohydrolase; TIGRFAM: dihydroorotase, multifunctional complex type YP_004162439.1 COGs: COG1410 methionine synthase I cobalamin-binding domain; InterPro IPR004223; KEGG: bth:BT_0249 5-methyltetrahydrofolate--homocysteine methyltransferase or methionine synthase; PFAM: Vitamin B12 dependent methionine synthase activation region; PRIAM: methionine synthase; SPTR: uncharacterized protein; PFAM: Vitamin B12 dependent methionine synthase, activation domain YP_004162440.1 COGs: COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog; InterPro IPR014284: IPR007627: IPR013249; KEGG: bfs:BF2975 RNA polymerase sigma factor; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; SPTR: uncharacterized protein; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family YP_004162441.1 KEGG: bth:BT_0247 hypothetical protein; SPTR: uncharacterized protein YP_004162442.1 COGs: COG1408 phosphohydrolase; InterPro IPR004843; KEGG: bth:BT_0246 calcineurin-like phosphoesterase domain-containing protein; PFAM: metallophosphoesterase; SPTR: uncharacterized protein; PFAM: Calcineurin-like phosphoesterase YP_004162443.1 KEGG: bfs:BF0845 ATP/GTP-binding site; PRIAM: alpha-galactosidase; SPTR: alpha-1,3-galactosidase B YP_004162444.1 InterPro IPR016518; KEGG: bfs:BF4255 hypothetical protein; PRIAM: alpha-L-fucosidase; SPTR: uncharacterized protein YP_004162445.1 KEGG: bfs:BF4254 hypothetical protein; SPTR: uncharacterized protein YP_004162446.1 COGs: COG4299 conserved hypothetical protein; KEGG: bfr:BF4455 hypothetical protein; SPTR: uncharacterized protein YP_004162447.1 KEGG: bth:BT_0664 hypothetical protein; SPTR: uncharacterized protein YP_004162448.1 KEGG: bfr:BF1484 hypothetical protein; SPTR: uncharacterized protein; manually curated YP_004162449.1 InterPro IPR012944; KEGG: dfe:Dfer_1844 RagB/SusD domain protein; PFAM: RagB/SusD domain protein; SPTR: RagB/SusD domain protein; PFAM: SusD family YP_004162450.1 InterPro IPR012910: IPR000531: IPR002173; KEGG: bfr:BF4451 hypothetical protein; PFAM: TonB-dependent receptor plug; TonB-dependent receptor; SPTR: uncharacterized protein; PFAM: TonB dependent receptor; TonB-dependent Receptor Plug Domain YP_004162451.1 COGs: COG3712 Fe2+-dicitrate sensor membrane component; InterPro IPR006860: IPR012373; KEGG: bfs:BF1413 anti-sigma factor; PFAM: FecR protein; SPTR: uncharacterized protein; PFAM: FecR protein YP_004162452.1 COGs: COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog; InterPro IPR014284: IPR014327: IPR007627: IPR013249; KEGG: bvu:BVU_0387 RNA polymerase ECF-type sigma factor; PFAM: Sigma-70 region 4 type 2; sigma-70 region 2 domain protein; SPTR: uncharacterized protein; TIGRFAM: RNA polymerase sigma-70 factor; RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; RNA polymerase sigma-70 factor, Bacteroides expansion family 1 YP_004162453.1 COGs: COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase; InterPro IPR002123; KEGG: bfs:BF2983 phospholipids biosynthesis-related protein; PFAM: phospholipid/glycerol acyltransferase; SMART: phospholipid/glycerol acyltransferase; SPTR: uncharacterized protein; PFAM: Acyltransferase; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferases YP_004162454.1 KEGG: bfs:BF3008 hypothetical protein; SPTR: uncharacterized protein YP_004162455.1 COGs: COG0641 Arylsulfatase regulator (Fe-S oxidoreductase); InterPro IPR007197; KEGG: bfr:BF3170 anaerobic sulfatase-maturase; PFAM: radical SAM protein; SPTR: uncharacterized protein; PFAM: Radical SAM superfamily YP_004162456.1 InterPro IPR019500; KEGG: bfs:BF3010 hypothetical protein; PFAM: peptidase S46; SPTR: uncharacterized protein; PFAM: peptidase S46 YP_004162457.1 InterPro IPR019500; KEGG: bfr:BF3172 hypothetical protein; PFAM: peptidase S46; SPTR: uncharacterized protein; PFAM: peptidase S46 YP_004162458.1 COGs: COG3118 Thioredoxin domain-containing protein; InterProIPR005746: IPR013766: IPR017937: IPR017936: IPR 006662; KEGG: bth:BT_0219 thioredoxin C-2; PFAM: Thioredoxin domain-containing protein; SPTR: Thioredoxin; TIGRFAM: thioredoxin; PFAM: Thioredoxin; TIGRFAM: thioredoxin YP_004162459.1 COGs: COG3118 Thioredoxin domain-containing protein; InterPro IPR013766: IPR017937: IPR017936; KEGG: bth:BT_0218 thioredoxin (TRX); PFAM: Thioredoxin domain-containing protein; SPTR: uncharacterized protein; PFAM: Thioredoxin; TIGRFAM: thioredoxin YP_004162460.1 COGs: COG1387 Histidinol phosphatase and related hydrolase of the PHP family; InterPro IPR010140: IPR004013; KEGG: bth:BT_1478 histidinol-phosphatase; PFAM: PHP domain protein; SPTR: uncharacterized protein; TIGRFAM: histidinol phosphate phosphatase; PFAM: PHP domain; TIGRFAM: histidinol phosphate phosphatase YP_004162461.1 COGs: COG0488 ATPase components of ABC transporter with duplicated ATPase domains; InterPro IPR003593: IPR003439: IPR017871; KEGG: bfr:BF1582 ABC transporter ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: uncharacterized protein; PFAM: ABC transporter YP_004162462.1 KEGG: bfr:BF1581 hypothetical protein; SPTR: uncharacterized protein YP_004162463.1 KEGG: bfs:BF1592 hypothetical protein; SPTR: uncharacterized protein YP_004162464.1 COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789: IPR001867; KEGG: bth:BT_1482 two-component system response regulator; PFAM: response regulator receiver; transcriptional regulator domain-containing protein; SMART: response regulator receiver; SPTR: uncharacterized protein; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal YP_004162465.1 COGs: COG5002 Signal transduction histidine kinase; InterProIPR003661: IPR003594: IPR018087: IPR005467: IPR 004358; KEGG: bfs:BF1589 two-component histidine kinase sensor protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: uncharacterized protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain YP_004162466.1 KEGG: bfr:BF1558 siderophore (surfactin) biosynthesis regulatory protein; SPTR: Siderophore biosynthesis regulatory protein YP_004162467.1 COGs: COG1253 Hemolysins and related protein containing CBS domains; InterPro IPR019862: IPR002550: IPR000644: IPR005170; KEGG: bfs:BF1572 CorC/HlyC family transporter associated protein; PFAM: protein of unknown function DUF21; CBS domain containing protein; transporter-associated region; SPTR: uncharacterized protein; TIGRFAM: gliding motility-associated protein GldE; PFAM: CBS domain; Domain of unknown function DUF21; Transporter associated domain; TIGRFAM: gliding motility-associated protein GldE YP_004162468.1 COGs: COG0629 Single-stranded DNA-binding protein; InterPro IPR011344: IPR000424; KEGG: bfs:BF1571 single-strand binding protein; PFAM: single-strand binding protein/Primosomal replication protein n; SPTR: Single-stranded DNA-binding protein; TIGRFAM: single-strand binding protein; PFAM: Single-strand binding protein family; TIGRFAM: single stranded DNA-binding protein (ssb) YP_004162469.1 COGs: COG1194 A/G-specific DNA glycosylase; InterPro IPR003265: IPR005760: IPR003651; KEGG: bfs:BF1569 A/G-specific adenine glycosylase; PFAM: HhH-GPD family protein; iron-sulfur cluster loop; SMART: HhH-GPD family protein; SPTR: uncharacterized protein; TIGRFAM: A/G-specific adenine glycosylase; PFAM: HhH-GPD superfamily base excision DNA repair protein; Iron-sulfur binding domain of endonuclease III; TIGRFAM: A/G-specific adenine glycosylase YP_004162470.1 COGs: COG0776 Bacterial nucleoid DNA-binding protein; InterPro IPR000119; KEGG: bfs:BF1568 histone-like DNA-binding protein HU1; PFAM: histone family protein DNA-binding protein; SMART: histone family protein DNA-binding protein; SPTR: uncharacterized protein; PFAM: Bacterial DNA-binding protein YP_004162471.1 COGs: COG1530 Ribonuclease G and E; InterPro IPR004659: IPR003029: IPR019307; KEGG: bfs:BF1566 ribonuclease E; PFAM: RNA-binding protein AU-1/Ribonuclease E/G; RNA binding S1 domain protein; SPTR: uncharacterized protein; TIGRFAM: ribonuclease, Rne/Rng family; PFAM: Ribonuclease E/G family; S1 RNA binding domain; TIGRFAM: ribonuclease, Rne/Rng family YP_004162472.1 COGs: COG1061 DNA or RNA helicase of superfamily II; InterPro IPR014001: IPR001650: IPR006935: IPR014021; KEGG: bvu:BVU_2967 helicase; PFAM: type III restriction protein res subunit; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; SPTR: helicase; PFAM: Helicase conserved C-terminal domain; type III restriction enzyme, res subunit YP_004162473.1 COGs: COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase; InterPro IPR018481: IPR018480; KEGG: bfr:BF3665 UDP-phosphate alpha-N-acetylglucosaminyltransferase; PFAM: glycosyl transferase, family 4, conserved region; SPTR: uncharacterized protein; PFAM: glycosyl transferase 4 YP_004162475.1 COGs: COG1089 GDP-D-mannose dehydratase; InterPro IPR006368: IPR001509: IPR020904; KEGG: bvu:BVU_3946 GDP-mannose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; SPTR: uncharacterized protein; TIGRFAM: GDP-mannose 4,6-dehydratase; PFAM: NAD dependent epimerase/dehydratase; TIGRFAM: GDP-mannose 4,6-dehydratase YP_004162476.1 COGs: COG0463 glycosyltransferase involved in cell wall biogenesis; InterPro IPR001173; KEGG: bfs:BF1024 glycosyltransferase; PFAM: glycosyl transferase 2; SPTR: glycosyltransferase; PFAM: glycosyl transferase 2 YP_004162477.1 COGs: COG0451 Nucleoside-diphosphate-sugar epimerase; InterPro IPR001509; KEGG: tye:THEYE_A0495 NDP-sugar dehydratase or epimerase, PFAM: NAD-dependent epimerase/dehydratase; SPTR: uncharacterized protein; PFAM: RmlD substrate binding domain YP_004162478.1 COGs: COG0438 glycosyltransferase; InterPro IPR001296; KEGG: clj:CLJU_c01990 glycosyltransferase; PFAM: glycosyl transferase group 1; SPTR: glycosyltransferase; PFAM: glycosyl transferases group 1 YP_004162479.1 KEGG: ecr:ECIAI1_2620 O-acyltransferase, transmembrane; SPTR: Wzy YP_004162480.1 COGs: COG3774 Mannosyltransferase OCH1; InterPro IPR007577; KEGG: pdi:BDI_1286 glycosyl transferase; PFAM: glycosyltransferase sugar-binding region containing DXD motif; SPTR: glycosyltransferase 32; PFAM: glycosyltransferase sugar-binding region containing DXD motif YP_004162481.1 COGs: COG0463 glycosyltransferase involved in cell wall biogenesis; InterPro IPR001173; KEGG: lhk:LHK_02953 glycosyltransferase; PFAM: glycosyl transferase 2; SPTR: uncharacterized protein; PFAM: glycosyl transferase 2 YP_004162482.1 InterPro IPR002797: IPR013838; KEGG: pdi:BDI_3621 flippase, involved in lipopolysaccharide biosynthesis; PFAM: polysaccharide biosynthesis protein; SPTR: flippase, involved in lipopolysaccharide biosynthesis; PFAM: polysaccharide biosynthesis protein YP_004162483.1 KEGG: bth:BT_1135 hypothetical protein; SPTR: uncharacterized protein YP_004162484.1 KEGG: tcu:Tcur_4038 two component LuxR family transcriptional regulator; SPTR: uncharacterized protein YP_004162485.1 COGs: COG0399 pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; InterPro IPR000653; KEGG: bfr:BF3659 aminotransferase; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; SPTR: Aminotransferase, DegT/DnrJ/EryC1/StrS family; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase YP_004162486.1 COGs: COG1024 Enoyl-CoA hydratase/carnithine racemase; InterPro IPR001753; KEGG: sen:SACE_3132 enoyl-CoA hydratase; PFAM: Enoyl-CoA hydratase/isomerase; SPTR: enoyl-CoA hydratase/isomerase; PFAM: Enoyl-CoA hydratase/isomerase YP_004162487.1 COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR002198: IPR020904: IPR002347; KEGG: ctc:CTC00130 3-ketoacyl-ACP reductase; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: 3-oxoacyl-[acyl-carrier protein] reductase; PFAM: short chain dehydrogenase YP_004162488.1 COGs: COG0332 3-oxoacyl-ACP; InterPro IPR004655: IPR013751: IPR013747; KEGG: glo:Glov_2408 3-oxoacyl-ACP synthase III; PFAM: 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III domain-containing protein; 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III; PRIAM: Beta-ketoacyl-acyl-carrier-protein synthase I; SPTR: Beta-ketoacyl-ACP synthase (FabH-like); TIGRFAM: 3-oxoacyl-ACP synthase III; PFAM: 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal; 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III; TIGRFAM: 3-oxoacyl-ACP synthase III YP_004162489.1 KEGG: kfl:Kfla_5854 GCN5-related N-acetyltransferase; SPTR: GCN5-related N-acetyltransferase YP_004162490.1 InterPro IPR008894; KEGG: pdi:BDI_3618 hypothetical protein; PFAM: WxcM-like domain-containing protein; SPTR: uncharacterized protein; PFAM: WxcM-like, C-terminal YP_004162491.1 InterPro IPR008894; KEGG: bfr:BF3663 hypothetical protein; PFAM: WxcM-like domain-containing protein; SPTR: WxcM-like, C-terminal protein; PFAM: WxcM-like, C-terminal YP_004162492.1 KEGG: aga:AgaP_AGAP011427 AGAP011427-PA; SPTR: uncharacterized protein YP_004162493.1 InterPro IPR006645; KEGG: bvu:BVU_2387 transcriptional regulator UpxY-like protein; PFAM: NGN domain-containing protein; SPTR: transcriptional regulator UpxY-like protein; PFAM: Transcription termination factor nusG YP_004162494.1 InterPro IPR002104; KEGG: bvu:BVU_2386 transposase; PFAM: integrase; SPTR: Transposase; PFAM: Phage integrase YP_004162495.1 COGs: COG1979 Uncharacterized oxidoreductase Fe-dependent alcohol dehydrogenase; InterPro IPR001670: IPR018211: IPR000623; KEGG: bvu:BVU_3015 Fe-dependent alcohol dehydrogenase oxidoreductase; PFAM: iron-containing alcohol dehydrogenase; SPTR: uncharacterized protein; PFAM: Iron-containing alcohol dehydrogenase YP_004162496.1 InterPro IPR000326; KEGG: bth:BT_1522 aureobasidin A resistance protein; PFAM: phosphoesterase PA-phosphatase related; SPTR: uncharacterized protein; PFAM: PAP2 superfamily YP_004162497.1 COGs: COG0558 phosphatidylglycerophosphate synthase; InterPro IPR000462; KEGG: bth:BT_1523 CDP-diacylglycerol-inositol 3-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; SPTR: uncharacterized protein; PFAM: CDP-alcohol phosphatidyltransferase YP_004162498.1 KEGG: bth:BT_1524 hypothetical protein; SPTR: uncharacterized protein; PFAM: GtrA-like protein YP_004162499.1 COGs: COG1267 phosphatidylglycerophosphatase A and related protein; InterPro IPR007686; KEGG: bth:BT_1525 phosphatidylglycerophosphatase A; PFAM: phosphatidylglycerophosphatase A; SPTR: phosphatidylglycerophosphatase A; PFAM: phosphatidylglycerophosphatase A YP_004162500.1 COGs: COG1260 Myo-inositol-1-phosphate synthase; InterPro IPR002587: IPR013021; KEGG: bth:BT_1526 myo-inositol-1-phosphate synthase; PFAM: Myo-inositol-1-phosphate synthase; Myo-inositol-1-phosphate synthase GAPDH domain protein; PRIAM: inositol-3-phosphate synthase; SPTR: uncharacterized protein; PFAM: Myo-inositol-1-phosphate synthase YP_004162501.1 KEGG: bth:BT_1527 hypothetical protein; SPTR: uncharacterized protein YP_004162502.1 COGs: COG5000 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation; InterProIPR000014: IPR003594: IPR003660: IPR013767: IPR 005467: IPR004358; KEGG: bth:BT_1528 two-component system sensor histidine kinase; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; PAS domain containing protein; SPTR: uncharacterized protein; PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; PAS fold; TIGRFAM: PAS domain S-box YP_004162503.1 COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterProIPR001789: IPR003593: IPR002078: IPR002197: IPR 020441; KEGG: bfr:BF1515 two-component system response regulator; PFAM: sigma-54 factor interaction domain-containing protein; response regulator receiver; helix-turn-helix Fis-type; SMART: response regulator receiver; AAA ATPase; SPTR: two component system response regulator; PFAM: Response regulator receiver domain; Bacterial regulatory protein, Fis family; Sigma-54 interaction domain YP_004162504.1 COGs: COG1538 Outer membrane protein; InterPro IPR003423; KEGG: bth:BT_1530 outer membrane protein OprM precursor; PFAM: outer membrane efflux protein; SPTR: uncharacterized protein; PFAM: Outer membrane efflux protein YP_004162505.1 COGs: COG0131 Imidazoleglycerol-phosphate dehydratase; InterProIPR005954: IPR006543: IPR006549: IPR000807: IPR 020565; KEGG: bth:BT_0203 imidazole glycerol-phosphate dehydratase/histidinol phosphatase; PFAM: imidazoleglycerol-phosphate dehydratase; PRIAM: Histidinol-phosphatase; SPTR: uncharacterized protein; TIGRFAM: histidinol-phosphatase; histidinol-phosphate phosphatase; hydrolase, HAD-superfamily, subfamily IIIA; PFAM: Imidazoleglycerol-phosphate dehydratase; TIGRFAM: HAD-superfamily hydrolase, subfamily IIIA; histidinol-phosphate phosphatase domain; histidinol-phosphatase YP_004162506.1 COGs: COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; InterPro IPR005861: IPR004839: IPR001917; KEGG: bth:BT_0202 histidinol-phosphate aminotransferase; PFAM: aminotransferase class I and II; SPTR: Histidinol-phosphate aminotransferase; TIGRFAM: histidinol-phosphate aminotransferase; PFAM: Aminotransferase class I and II; TIGRFAM: histidinol-phosphate aminotransferase YP_004162507.1 COGs: COG0141 Histidinol dehydrogenase; InterPro IPR012131: IPR001692; KEGG: bfs:BF3029 histidinol dehydrogenase; PFAM: Histidinol dehydrogenase; PRIAM: Histidinol dehydrogenase; SPTR: Histidinol dehydrogenase; TIGRFAM: histidinol dehydrogenase; PFAM: Histidinol dehydrogenase; TIGRFAM: histidinol dehydrogenase YP_004162508.1 COGs: COG0040 ATP phosphoribosyltransferase; InterPro IPR013820: IPR013115: IPR020621: IPR018198; KEGG: bth:BT_0200 ATP phosphoribosyltransferase; PFAM: ATP phosphoribosyltransferase catalytic region; Histidine biosynthesis protein HisG domain; PRIAM: ATP phosphoribosyltransferase; SPTR: ATP phosphoribosyltransferase; TIGRFAM: ATP phosphoribosyltransferase; PFAM: HisG, C-terminal domain; ATP phosphoribosyltransferase; TIGRFAM: ATP phosphoribosyltransferase, C-terminal domain; ATP phosphoribosyltransferase YP_004162509.1 InterPro IPR006683; KEGG: bfs:BF3031 thioesterase; PFAM: thioesterase superfamily protein; SPTR: uncharacterized protein; PFAM: Thioesterase superfamily; TIGRFAM: uncharacterized domain 1 YP_004162510.1 COGs: COG0738 Fucose permease; InterPro IPR005275: IPR011701; KEGG: bfs:BF0215 L-fucose permease; PFAM: major facilitator superfamily MFS_1; SPTR: uncharacterized protein; TIGRFAM: L-fucose transporter; PFAM: Major Facilitator Superfamily; TIGRFAM: L-fucose:H+ symporter permease YP_004162511.1 COGs: COG3254 conserved hypothetical protein; InterPro IPR008000; KEGG: bth:BT_1276 hypothetical protein; PFAM: protein of unknown function DUF718; SPTR: uncharacterized protein; PFAM: Domain of unknown function (DUF718) YP_004162512.1 COGs: COG1070 Sugar (pentulose and hexulose) kinase; InterPro IPR018484; KEGG: bfs:BF0214 fuculokinase; PFAM: Carbohydrate kinase, FGGY-like; SPTR: uncharacterized protein; PFAM: FGGY family of carbohydrate kinases, N-terminal domain; FGGY family of carbohydrate kinases, C-terminal domain YP_004162513.1 COGs: COG0235 Ribulose-5-phosphate 4-epimerase and related epimerase and aldolase; InterPro IPR001303; KEGG: bfs:BF0213 aldolase; PFAM: class II aldolase/adducin family protein; SPTR: uncharacterized protein; PFAM: Class II Aldolase and Adducin N-terminal domain YP_004162514.1 COGs: COG1454 Alcohol dehydrogenase class IV; InterPro IPR013460: IPR001670: IPR018211; KEGG: bfs:BF0212 L-1,2-propanediol oxidoreductase; PFAM: iron-containing alcohol dehydrogenase; SPTR: lactaldehyde reductase; TIGRFAM: lactaldehyde reductase; PFAM: Iron-containing alcohol dehydrogenase; TIGRFAM: lactaldehyde reductase YP_004162515.1 COGs: COG2407 L-fucose isomerase and related protein; InterPro IPR005763: IPR012888: IPR012889: IPR015888; KEGG: bvu:BVU_1373 L-fucose isomerase; PFAM: L-fucose isomerase _2 domain protein; L-fucose isomerase _1 domain protein; L-fucose isomerase-like-like; PRIAM: L-fucose isomerase; SPTR: L-fucose isomerase; TIGRFAM: L-fucose isomerase; PFAM: L-fucose isomerase, C-terminal domain; L-fucose isomerase, first N-terminal domain; L-fucose isomerase, second N-terminal domain; TIGRFAM: L-fucose isomerase YP_004162516.1 COGs: COG2188 Transcriptional regulators; InterPro IPR000524; KEGG: bvu:BVU_1374 transcriptional regulator, FucR; PFAM: regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; SPTR: uncharacterized protein; PFAM: Bacterial regulatory proteins, gntR family YP_004162517.1 COGs: COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog; InterPro IPR014284: IPR007627: IPR013249; KEGG: dfe:Dfer_2829 RNA polymerase, sigma-24 subunit, ECF subfamily; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; SPTR: RNA polymerase sigma-70 factor, ECF subfamily; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; RNA polymerase sigma-70 factor, Bacteroides expansion family 1 YP_004162518.1 InterPro IPR000866: IPR017937: IPR017936: IPR006662; KEGG: bfs:BF2739 lipoprotein/thioderoxin; PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; SPTR: uncharacterized protein; PFAM: AhpC/TSA family YP_004162520.1 COGs: COG4845 Chloramphenicol O-acetyltransferase; InterPro IPR001707; KEGG: bvu:BVU_1202 chloramphenicol acetyltransferase; PFAM: chloramphenicol acetyltransferase; SPTR: uncharacterized protein; PFAM: Chloramphenicol acetyltransferase YP_004162521.1 COGs: COG4232 Thiol:disulfide interchange protein; InterPro IPR003834: IPR017936; KEGG: bfs:BF3033 exported cytochrome c biogenesis-related protein; PFAM: cytochrome c biogenesis protein transmembrane region; PRIAM: Protein-disulfide reductase; SPTR: uncharacterized protein; PFAM: Cytochrome C biogenesis protein transmembrane region; Protein of unknown function, DUF255 YP_004162522.1 InterPro IPR013097; KEGG: bfs:BF3034 hypothetical protein; PFAM: Stress responsive alpha-beta barrel domain-containing protein; SPTR: uncharacterized protein; PFAM: Stress responsive A/B Barrel Domain YP_004162523.1 COGs: COG0572 Uridine kinase; InterPro IPR000764: IPR017975; KEGG: bfs:BF3035 uridine kinase; SPTR: Uridine kinase; TIGRFAM: uridine kinase; PFAM: phosphoribulokinase / Uridine kinase; TIGRFAM: uridine kinase YP_004162524.1 COGs: COG4623 soluble lytic transglycosylase fused to an ABC-type amino acid-binding protein; InterPro IPR001638: IPR008258; KEGG: bth:BT_0183 transglycosylase; PFAM: Lytic transglycosylase catalytic; extracellular solute-binding protein family 3; SMART: extracellular solute-binding protein family 3; SPTR: uncharacterized protein; PFAM: Transglycosylase SLT domain; Bacterial extracellular solute-binding proteins, family 3 YP_004162525.1 COGs: COG3682 transcriptional regulator protein; InterPro IPR005650; KEGG: fjo:Fjoh_1362 CopY family transcriptional regulator; PFAM: Penicillinase repressor; SPTR: CopY family transcriptional regulator; PFAM: Penicillinase repressor YP_004162526.1 InterPro IPR008756: IPR020904; KEGG: sli:Slin_3430 peptidase M56 BlaR1; PFAM: peptidase M56 BlaR1; SPTR: uncharacterized protein; PFAM: BlaR1 peptidase M56 YP_004162527.1 COGs: COG1410 methionine synthase I cobalamin-binding domain; InterProIPR011822: IPR003726: IPR000489: IPR003759: IPR 006158; KEGG: bfs:BF3039 5-methyltetrahydrofolate--homocysteine methyltransferase; PFAM: homocysteine S-methyltransferase; dihydropteroate synthase DHPS; methionine synthase B12-binding module cap domain protein; cobalamin B12-binding domain protein; SPTR: methionine synthase; TIGRFAM: methionine synthase; PFAM: Pterin binding enzyme; B12 binding domain; Homocysteine S-methyltransferase; TIGRFAM: methylmalonyl-CoA mutase C-terminal domain; 5-methyltetrahydrofolate--homocysteine methyltransferase YP_004162528.1 COGs: COG0691 tmRNA-binding protein; InterPro IPR000037: IPR020081; KEGG: bth:BT_0179 SsrA-binding protein; PFAM: SmpB protein; SPTR: SsrA-binding protein; TIGRFAM: SsrA-binding protein; PFAM: SmpB protein; TIGRFAM: SsrA-binding protein YP_004162529.1 KEGG: bfs:BF3041 hypothetical protein; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF1282) YP_004162530.1 KEGG: bth:BT_0177 hypothetical protein; SPTR: uncharacterized protein YP_004162531.1 KEGG: bfs:BF3043 hypothetical protein; SPTR: uncharacterized protein YP_004162532.1 COGs: COG0822 NifU homolog involved in Fe-S cluster formation; KEGG: bth:BT_0174 hypothetical protein; SPTR: NifU-related domain containing protein YP_004162533.1 KEGG: bvu:BVU_2514 hypothetical protein; SPTR: uncharacterized protein YP_004162534.1 COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR018060; KEGG: bfs:BF2137 AraC family transcriptional regulator; SMART: Helix-turn-helix, AraC domain; SPTR: uncharacterized protein YP_004162535.1 COGs: COG1454 Alcohol dehydrogenase class IV; InterPro IPR001670; KEGG: mmp:MMP0802 iron-containing alcohol dehydrogenase; PFAM: iron-containing alcohol dehydrogenase; SPTR: Iron-containing alcohol dehydrogenase; PFAM: Iron-containing alcohol dehydrogenase YP_004162536.1 COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR018060: IPR000005; KEGG: bfs:BF2137 AraC family transcriptional regulator; PFAM: helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: uncharacterized protein; manually curated; PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family YP_004162537.1 COGs: COG0655 Multimeric flavodoxin WrbA; InterPro IPR005025; KEGG: fsu:Fisuc_1718 NADPH-dependent FMN reductase; PFAM: NADPH-dependent FMN reductase; SPTR: uncharacterized protein; PFAM: NADPH-dependent FMN reductase YP_004162538.1 COGs: COG4925 conserved hypothetical protein; KEGG: sli:Slin_2181 hypothetical protein; SPTR: uncharacterized protein YP_004162539.1 COGs: COG0110 Acetyltransferase (isoleucine patch superfamily); InterPro IPR001451; KEGG: pdi:BDI_1427 acetyltransferase; SPTR: Acetyltransferase; PFAM: Bacterial transferase hexapeptide (three repeats) YP_004162540.1 COGs: COG2768 Uncharacterized Fe-S center protein; KEGG: pdi:BDI_0351 uncharacterized Fe-S center protein, ferredoxin; SPTR: uncharacterized protein YP_004162541.1 COGs: COG4206 Outer membrane cobalamin receptor protein; InterPro IPR012910: IPR000531; KEGG: bfr:BF4297 TonB-dependent outer membrane receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor plug; SPTR: uncharacterized protein; PFAM: TonB-dependent Receptor Plug Domain; TonB dependent receptor YP_004162542.1 COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR000792; KEGG: bth:BT_0156 transcriptional regulator; PFAM: regulatory protein LuxR; SMART: regulatory protein LuxR; SPTR: uncharacterized protein; PFAM: Bacterial regulatory proteins, luxR family YP_004162543.1 COGs: COG0482 tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase contains the PP-loop ATPase domain; InterPro IPR004506; KEGG: bth:BT_0155 tRNA-specific 2-thiouridylase MnmA; SPTR: uncharacterized protein; TIGRFAM: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; PFAM: tRNA methyl transferase; TIGRFAM: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase YP_004162544.1 COGs: COG2873 O-acetylhomoserine sulfhydrylase; InterPro IPR006235: IPR000277; KEGG: pdi:BDI_2552 O-acetylhomoserine (thiol)-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; PRIAM: Cysteine synthase; SPTR: O-acetylhomoserine (Thiol)-lyase; TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism PLP-dependent enzyme; TIGRFAM: OAH/OAS sulfhydrylase YP_004162545.1 COGs: COG0793 Periplasmic protease; InterPro IPR005151; KEGG: bfs:BF1979 hypothetical protein; PFAM: peptidase S41; SMART: peptidase S41; SPTR: uncharacterized protein; PFAM: peptidase S41 YP_004162546.1 KEGG: bfs:BF1340 hypothetical protein; SPTR: uncharacterized protein YP_004162547.1 COGs: COG0627 esterase; InterPro IPR000801; KEGG: bth:BT_0152 acetyl esterase (acetylxylosidase); PFAM: esterase; SPTR: uncharacterized protein; PFAM: esterase YP_004162548.1 COGs: COG1253 Hemolysins and related protein containing CBS domains; InterPro IPR000644: IPR002550: IPR005170; KEGG: bfs:BF1334 CorC/HlyC family transporter; PFAM: protein of unknown function DUF21; CBS domain containing protein; transporter-associated region; SMART: CBS domain containing protein; SPTR: uncharacterized protein; manually curated; PFAM: CBS domain; Domain of unknown function DUF21; Transporter associated domain YP_004162549.1 KEGG: bfs:BF1333 hypothetical protein; SPTR: uncharacterized protein; PFAM: Uncharacterized lipoprotein NlpE involved in copper resistance YP_004162550.1 InterPro IPR005632; KEGG: bth:BT_1613 hypothetical protein; PFAM: outer membrane chaperone Skp (OmpH); SPTR: uncharacterized protein; PFAM: Outer membrane protein (OmpH-like) YP_004162551.1 KEGG: bfs:BF3078 hypothetical protein; SPTR: uncharacterized protein YP_004162552.1 COGs: COG2195 Di- and tripeptidase; InterPro IPR001160: IPR002933: IPR011650; KEGG: bth:BT_1615 aminoacyl-histidine dipeptidase; PFAM: peptidase dimerisation domain protein; peptidase M20; PRIAM: Xaa-His dipeptidase; SPTR: uncharacterized protein; TIGRFAM: aminoacyl-histidine dipeptidase; PFAM: peptidase M20/M25/M40; peptidase dimerisation domain; TIGRFAM: aminoacyl-histidine dipeptidase YP_004162553.1 COGs: COG2374 extracellular nuclease; InterPro IPR005135; KEGG: bth:BT_1616 hypothetical protein; PFAM: Endonuclease/exonuclease/phosphatase; SPTR: uncharacterized protein; PFAM: Endonuclease/Exonuclease/phosphatase YP_004162554.1 InterPro IPR000326; KEGG: bfs:BF3253 hypothetical protein; PFAM: phosphoesterase PA-phosphatase related; SMART: phosphoesterase PA-phosphatase related; SPTR: uncharacterized protein; PFAM: PAP2 superfamily YP_004162555.1 COGs: COG1368 phosphoglycerol transferase and related protein alkaline phosphatase superfamily; InterPro IPR000917: IPR012160; KEGG: bfr:BF3431 sulfatase; PFAM: sulfatase; SPTR: uncharacterized protein; PFAM: Sulfatase YP_004162556.1 COGs: COG0176 Transaldolase; InterPro IPR004731: IPR001585: IPR018225; KEGG: bth:BT_1658 translaldolase; PFAM: Transaldolase; SPTR: uncharacterized protein; TIGRFAM: transaldolase; PFAM: Transaldolase; TIGRFAM: fructose-6-phosphate aldolase, TalC/MipB family YP_004162557.1 KEGG: bfr:BF0258 hypothetical protein; SPTR: uncharacterized protein YP_004162558.1 COGs: COG1119 ABC-type molybdenum transport system ATPase component/photorepair protein PhrA; InterPro IPR003593: IPR003439: IPR017871; KEGG: bth:BT_1662 molybdenum transport ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: uncharacterized protein; PFAM: ABC transporter YP_004162559.1 KEGG: ppp:PHYPADRAFT_160448 hypothetical protein; SPTR: Predicted protein YP_004162560.1 COGs: COG1523 type II secretory pathway pullulanase PulA and related glycosidase; InterProIPR006589: IPR011840: IPR004193: IPR006047: IPR 006048: IPR002355; KEGG: bfs:BF3100 exported amylase; PFAM: glycoside hydrolase 13 domain protein; alpha amylase catalytic region; alpha amylase all-beta; SMART: alpha amylase catalytic sub domain; SPTR: Pullulanase, type I; TIGRFAM: pullulanase, type I; PFAM: Carbohydrate-binding module 48 (Isoamylase N-terminal domain); Alpha amylase, catalytic domain; TIGRFAM: pullulanase, type I YP_004162561.1 COGs: COG0817 Holliday junction resolvasome endonuclease subunit; InterPro IPR002176: IPR020563; KEGG: bth:BT_1664 Holliday junction resolvase; PFAM: Crossover junction endodeoxyribonuclease RuvC; PRIAM: Crossover junction endodeoxyribonuclease; SPTR: Crossover junction endodeoxyribonuclease ruvC; TIGRFAM: crossover junction endodeoxyribonuclease RuvC; PFAM: Crossover junction endodeoxyribonuclease RuvC; TIGRFAM: crossover junction endodeoxyribonuclease RuvC YP_004162562.1 KEGG: bth:BT_1665 hypothetical protein; SPTR: uncharacterized protein YP_004162563.1 InterPro IPR012944; KEGG: bfr:BF2139 hypothetical protein; PFAM: RagB/SusD domain protein; SPTR: uncharacterized protein; PFAM: SusD family YP_004162564.1 InterPro IPR012910: IPR000531; KEGG: bfs:BF2195 hypothetical protein; PFAM: TonB-dependent receptor plug; TonB-dependent receptor; SPTR: uncharacterized protein; PFAM: TonB-dependent Receptor Plug Domain; TonB dependent receptor YP_004162565.1 InterPro IPR001818; KEGG: bfr:BF2137 hypothetical protein; PFAM: peptidase M10A and M12B matrixin and adamalysin; SPTR: uncharacterized protein YP_004162567.1 COGs: COG0016 Phenylalanyl-tRNA synthetase alpha subunit; InterPro IPR004529: IPR004188: IPR002319: IPR006195; KEGG: bth:BT_1669 phenylalanyl-tRNA synthetase subunit alpha; PFAM: phenylalanyl-tRNA synthetase class IIc; aminoacyl tRNA synthetase class II domain protein; SPTR: uncharacterized protein; TIGRFAM: phenylalanyl-tRNA synthetase, alpha subunit; PFAM: tRNA synthetases class II core domain (F); Aminoacyl tRNA synthetase class II, N-terminal domain; TIGRFAM: phenylalanyl-tRNA synthetase, alpha subunit YP_004162568.1 COGs: COG2814 Arabinose efflux permease; InterPro IPR011701; KEGG: bth:BT_1670 transmembrane transport protein; PFAM: major facilitator superfamily MFS_1; SPTR: uncharacterized protein; PFAM: Major Facilitator Superfamily YP_004162569.1 COGs: COG0177 EndoIII-related endonuclease; InterPro IPR003265: IPR003651: IPR005759: IPR004036; KEGG: bfs:BF3106 endonuclease; PFAM: HhH-GPD family protein; iron-sulfur cluster loop; PRIAM: DNA-(apurinic or apyrimidinic site) lyase; SMART: HhH-GPD family protein; iron-sulfur cluster loop; SPTR: uncharacterized protein; TIGRFAM: endonuclease III; PFAM: HhH-GPD superfamily base excision DNA repair protein; Helix-hairpin-helix motif; TIGRFAM: endonuclease III YP_004162570.1 COGs: COG0126 3-phosphoglycerate kinase; InterPro IPR001576; KEGG: bth:BT_1672 phosphoglycerate kinase; PFAM: phosphoglycerate kinase; PRIAM: phosphoglycerate kinase; SPTR: phosphoglycerate kinase; PFAM: phosphoglycerate kinase YP_004162571.1 InterPro IPR010870; KEGG: pru:PRU_1514 hypothetical protein; PFAM: phosphate-selective porin O and P; SPTR: phosphate-selective porin O and P family protein; PFAM: phosphate-selective porin O and P YP_004162572.1 COGs: COG2704 Anaerobic C4-dicarboxylate transporter; InterPro IPR004668; KEGG: pru:PRU_1070 anaerobic C4-dicarboxylate membrane transporter DcuB; PFAM: anaerobic c4-dicarboxylate membrane transporter; SPTR: Anaerobic C4-dicarboxylate membrane transporter DcuB; TIGRFAM: anaerobic c4-dicarboxylate antiporter, Dcu family; PFAM: Anaerobic c4-dicarboxylate membrane transporter; TIGRFAM: anaerobic c4-dicarboxylate membrane transporter family protein YP_004162573.1 COGs: COG0471 Di- and tricarboxylate transporter; InterPro IPR001898; KEGG: bth:BT_3739 Na+/dicarboxylate or sulfate symporter; PFAM: sodium/sulphate symporter; SPTR: Na+/dicarboxylate or sulfate symporter; TIGRFAM: anion transporter; manually curated; PFAM: Sodium:sulfate symporter transmembrane region; TIGRFAM: anion transporter YP_004162574.1 InterPro IPR019734: IPR001440: IPR013026; KEGG: bfs:BF3111 hypothetical protein; PFAM: hypothetical protein; SPTR: uncharacterized protein; PFAM: Tetratricopeptide repeat YP_004162575.1 COGs: COG0424 Nucleotide-binding protein implicated in inhibition of septum formation; InterPro IPR003697; KEGG: bth:BT_1676 Maf-like protein; PFAM: Maf family protein; SPTR: Maf-like protein BACSTE_01667; TIGRFAM: maf protein; PFAM: Maf-like protein; TIGRFAM: MAF protein YP_004162576.1 COGs: COG1778 Low specificity phosphatase (HAD superfamily); InterPro IPR010023: IPR006549; KEGG: bfs:BF3121 lipopolysaccharide biosynthesis-related protein; SPTR: uncharacterized protein; TIGRFAM: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family; hydrolase, HAD-superfamily, subfamily IIIA; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family; HAD-superfamily hydrolase, subfamily IIIA YP_004162577.1 COGs: COG5495 conserved hypothetical protein; InterPro IPR018931; KEGG: bfr:BF3283 hypothetical protein; PFAM: Domain of unknown function DUF2520; SPTR: uncharacterized protein; PFAM: Domain of unknown function (DUF2520); Shikimate / quinate 5-dehydrogenase YP_004162578.1 KEGG: bfs:BF3123 hypothetical protein; SPTR: uncharacterized protein YP_004162579.1 COGs: COG0778 Nitroreductase; InterPro IPR000415; KEGG: bth:BT_1680 NADH dehydrogenase/NAD(P)H nitroreductase; PFAM: nitroreductase; SPTR: uncharacterized protein; PFAM: Nitroreductase YP_004162580.1 KEGG: bfs:BF3126 hypothetical protein; SPTR: uncharacterized protein YP_004162581.1 COGs: COG0296 1 4-alpha-glucan branching enzyme; InterPro IPR006589: IPR006047; KEGG: bfr:BF3304 alpha-amylase; PFAM: alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; SPTR: Lipoprotein; PFAM: Alpha amylase, catalytic domain YP_004162582.1 KEGG: pru:PRU_2684 hypothetical protein; SPTR: uncharacterized protein YP_004162583.1 KEGG: bth:BT_3700 outer membrane protein SusE; SPTR: Outer membrane protein YP_004162584.1 InterPro IPR012944; KEGG: pru:PRU_2682 outer membrane protein SusD; PFAM: RagB/SusD domain protein; SPTR: Outer membrane protein; PFAM: SusD family YP_004162585.1 InterPro IPR012910: IPR000531; KEGG: pru:PRU_2681 outer membrane protein SusC; PFAM: TonB-dependent receptor plug; TonB-dependent receptor; SPTR: Outer membrane protein SusC; PFAM: TonB-dependent Receptor Plug Domain; TonB dependent receptor YP_004162586.1 COGs: COG3867 Arabinogalactan endo-1 4-beta-galactosidase; InterPro IPR011683; KEGG: pru:PRU_2676 family 53 glycosyl hydrolase; PFAM: glycosyl hydrolase 53 domain protein; PRIAM: Arabinogalactan endo-1,4-beta-galactosidase; SPTR: uncharacterized protein; PFAM: glycosyl hydrolase 53 YP_004162587.1 COGs: COG0642 Signal transduction histidine kinase; InterProIPR003661: IPR003594: IPR018060: IPR011110: IPR 011123: IPR000005: IPR005467: IPR004358; KEGG: bth:BT_4673 two-component system sensor histidine kinase; PFAM: ATP-binding region ATPase domain protein; two component regulator three Y domain-containing protein; two component regulator propeller; histidine kinase A domain protein; helix-turn-helix- domain containing protein AraC type; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; Helix-turn-helix, AraC domain; SPTR: two-component system sensor histidine kinase; PFAM: Y_Y_Y domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; two component regulator propeller; His Kinase A (phosphoacceptor) domain; Bacterial regulatory helix-turn-helix proteins, AraC family YP_004162588.1 COGs: COG1609 Transcriptional regulators; InterPro IPR000843: IPR001761; KEGG: bfs:BF3147 LacI family transcriptional regulator; PFAM: periplasmic binding protein/LacI transcriptional regulator; regulatory protein LacI; SMART: regulatory protein LacI; SPTR: uncharacterized protein; manually curated; PFAM: Bacterial regulatory proteins, lacI family; family YP_004162589.1 COGs: COG2211 Na+/melibiose symporter and related transporter; InterPro IPR011701; KEGG: bvu:BVU_1386 sugar transporter; PFAM: major facilitator superfamily MFS_1; SPTR: uncharacterized protein; PFAM: Major Facilitator Superfamily YP_004162590.1 COGs: COG1554 Trehalose and maltose hydrolase (possible phosphorylase); InterPro IPR005196: IPR005195: IPR005194: IPR017045; KEGG: bfr:BF3310 maltose phosphorylase; PFAM: glycoside hydrolase 65; glycoside hydrolase 65 domain protein; SPTR: uncharacterized protein; PFAM: glycosyl hydrolase 65, C-terminal domain; glycosyl hydrolase 65, N-terminal domain; glycosyl hydrolase 65 central catalytic domain YP_004162591.1 COGs: COG1883 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase beta subunit; InterPro IPR005661; KEGG: bvu:BVU_1976 oxaloacetate decarboxylase beta chain; PFAM: Na+transporting methylmalonyl-CoA/oxaloacetate decarboxylase beta subunit; PRIAM: Oxaloacetate decarboxylase; SPTR: uncharacterized protein; TIGRFAM: sodium ion-translocating decarboxylase, beta subunit; PFAM: subunit; TIGRFAM: sodium ion-translocating decarboxylase, beta subunit YP_004162592.1 COGs: COG5016 Pyruvate/oxaloacetate carboxyltransferase; InterPro IPR000891: IPR000089: IPR001882: IPR000150; KEGG: bth:BT_1697 pyruvate carboxylase subunit B; PFAM: biotin/lipoyl attachment domain-containing protein; pyruvate carboxyltransferase; PRIAM: Pyruvate carboxylase; SPTR: uncharacterized protein; PFAM: HMGL-like; Conserved carboxylase domain; Biotin-requiring enzyme YP_004162593.1 InterPro IPR005899; KEGG: bfs:BF2821 hypothetical protein; PFAM: sodium pump decarboxylase gamma subunit; SPTR: uncharacterized protein; PFAM: Oxaloacetate decarboxylase, gamma chain; TIGRFAM: sodium pump decarboxylases, gamma subunit YP_004162594.1 InterPro IPR005902; KEGG: bth:BT_3199 non-specific DNA-binding protein; SPTR: uncharacterized protein; TIGRFAM: DNA-binding protein; PFAM: Bacterial DNA-binding protein; TIGRFAM: DNA-binding protein, histone-like YP_004162595.1 COGs: COG1343 Uncharacterized protein predicted to be involved in DNA repair; InterPro IPR021127; KEGG: pdi:BDI_1184 hypothetical protein; SPTR: Uncharacterized protein predicted to be involved in DNA repair; TIGRFAM: CRISPR-associated protein Cas2; PFAM: CRISPR associated protein Cas2; TIGRFAM: CRISPR-associated endoribonuclease Cas2 YP_004162596.1 COGs: COG1518 Uncharacterized protein predicted to be involved in DNA repair; InterPro IPR019856: IPR002729; KEGG: pdi:BDI_1183 hypothetical protein; PFAM: protein of unknown function DUF48; SPTR: uncharacterized protein; TIGRFAM: CRISPR-associated protein Cas1; PFAM: CRISPR associated protein Cas1; TIGRFAM: CRISPR-associated endonuclease Cas1, DVULG subtype; CRISPR-associated endonuclease Cas1 YP_004162597.1 COGs: COG1468 RecB family exonuclease; InterPro IPR013343; KEGG: pdi:BDI_1182 RecB family exonuclease; SPTR: Exonuclease; TIGRFAM: CRISPR-associated protein Cas4; PFAM: Domain of unknown function DUF83; TIGRFAM: CRISPR-associated protein Cas4 YP_004162598.1 COGs: COG3649 Uncharacterized protein predicted to be involved in DNA repair; InterPro IPR006482: IPR013418; KEGG: pdi:BDI_1181 hypothetical protein; PFAM: CRISPR-associated protein TM1801; SPTR: Uncharacterized protein predicted to be involved in DNA repair; TIGRFAM: CRISPR-associated protein, Csd2 family; CRISPR-associated protein, CT1132 family; PFAM: Family of unknown function (DUF694); TIGRFAM: CRISPR-associated protein, CT1132 family; CRISPR-associated protein, Csd2 family; CRISPR-associated protein, Csh2 family YP_004162599.1 InterPro IPR010144; KEGG: mta:Moth_0496 CRISPR-associated Csd1 family protein; PFAM: CRISPR-associated protein CT1133; SPTR: CRISPR-associated protein, CT1133; TIGRFAM: CRISPR-associated protein, Csd1 family; PFAM: CRISPR-associated protein (Cas_Csd1); TIGRFAM: CRISPR-associated protein, Csd1 family YP_004162600.1 InterPro IPR013422: IPR010155: IPR021124; KEGG: mta:Moth_0497 CRISPR-associated Csd1 family protein; PFAM: CRISPR-associated protein, Cas5; SPTR: CRISPR-associated protein, CT1134; TIGRFAM: CRISPR-associated protein Cas5 family; CRISPR-associated protein Cas5; PFAM: CRISPR-associated protein (Cas_Cas5); TIGRFAM: CRISPR-associated protein Cas5, Dvulg subtype; CRISPR-associated protein Cas5, N-terminal domain YP_004162601.1 COGs: COG1203 helicase; InterProIPR014001: IPR001650: IPR006483: IPR006474: IPR 006674: IPR006935: IPR014021; KEGG: mta:Moth_0498 CRISPR-associated helicase Cas3 family protein protein; PFAM: type III restriction protein res subunit; metal-dependent phosphohydrolase HD sub domain; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; SPTR: CRISPR-associated helicase Cas3, core; TIGRFAM: CRISPR-associated HD domain protein; CRISPR-associated helicase Cas3; PFAM: Helicase conserved C-terminal domain; HD domain; DEAD/DEAH box helicase; TIGRFAM: CRISPR-associated helicase Cas3; CRISPR-associated endonuclease Cas3-HD; uncharacterized domain HDIG YP_004162602.1 KEGG: hso:HS_1527 hypothetical protein; SPTR: uncharacterized protein YP_004162604.1 KEGG: bvu:BVU_0275 hypothetical protein; SPTR: uncharacterized protein YP_004162605.1 COGs: COG4108 peptide chain release factor RF-3; InterPro IPR004548: IPR005225: IPR000795; KEGG: bvu:BVU_0074 peptide chain release factor 3; PFAM: protein synthesis factor GTP-binding; SPTR: uncharacterized protein; TIGRFAM: peptide chain release factor 3; small GTP-binding protein; PFAM: Elongation factor Tu GTP binding domain; TIGRFAM: small GTP-binding protein domain; peptide chain release factor 3 YP_004162606.1 COGs: COG1091 dTDP-4-dehydrorhamnose reductase; InterPro IPR005913; KEGG: bfs:BF1296 dTDP-dehydrorhamnose reductase; PFAM: dTDP-4-dehydrorhamnose reductase; SPTR: dTDP-4-dehydrorhamnose reductase; TIGRFAM: dTDP-4-dehydrorhamnose reductase; PFAM: RmlD substrate binding domain; TIGRFAM: dTDP-4-dehydrorhamnose reductase YP_004162607.1 KEGG: bfs:BF1295 hypothetical protein; SPTR: uncharacterized protein YP_004162608.1 InterPro IPR001123; KEGG: bfs:BF1294 transmembrane protein; PFAM: Lysine exporter protein (LYSE/YGGA); SPTR: uncharacterized protein; PFAM: LysE type translocator YP_004162609.1 KEGG: bfs:BF3153 hypothetical protein; SPTR: uncharacterized protein YP_004162610.1 COGs: COG0046 phosphoribosylformylglycinamidine (FGAM) synthase synthetase domain; InterPro IPR000728: IPR010918: IPR017926; KEGG: bth:BT_1733 phosphoribosylformylglycinamidine synthase; PFAM: AIR synthase related protein domain protein; AIR synthase related protein; PRIAM: phosphoribosylformylglycinamidine synthase; SPTR: uncharacterized protein; PFAM: AIR synthase related protein, N-terminal domain; AIR synthase related protein, C-terminal domain; TIGRFAM: phosphoribosylformylglycinamidine synthase, single chain form YP_004162611.1 COGs: COG0642 Signal transduction histidine kinase; InterProIPR003661: IPR003594: IPR001789: IPR018060: IPR 011110: IPR011123: IPR000005: IPR018062: IPR005467: IPR004358; KEGG: bfs:BF3155 two-component system sensor kinase/response regulator fusion protein; PFAM: ATP-binding region ATPase domain protein; two component regulator three Y domain-containing protein; two component regulator propeller; histidine kinase A domain protein; response regulator receiver; helix-turn-helix- domain containing protein AraC type; SMART: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; Helix-turn-helix, AraC domain; SPTR: uncharacterized protein; PFAM: Y_Y_Y domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; two component regulator propeller; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; Bacterial regulatory helix-turn-helix proteins, AraC family YP_004162612.1 COGs: COG2059 Chromate transport protein ChrA; InterPro IPR003370; KEGG: bfs:BF3156 chromate transport protein; PFAM: Chromate transporter; SPTR: uncharacterized protein; PFAM: Chromate transporter YP_004162613.1 COGs: COG2059 Chromate transport protein ChrA; InterPro IPR003370; KEGG: bfr:BF3318 chromate transport protein; PFAM: Chromate transporter; SPTR: uncharacterized protein; PFAM: Chromate transporter YP_004162614.1 COGs: COG1649 conserved hypothetical protein; InterPro IPR003790; KEGG: bfr:BF3319 secreted protein; PFAM: protein of unknown function DUF187; SPTR: uncharacterized protein; PFAM: Uncharacterised BCR, COG1649 YP_004162615.1 COGs: COG0178 excinuclease ATPase subunit; InterPro IPR004602: IPR003439: IPR017871; KEGG: bfr:BF3320 excinuclease ABC subunit A; PFAM: ABC transporter related; SPTR: excinuclease ABC, A subunit; TIGRFAM: excinuclease ABC, A subunit; PFAM: ABC transporter; TIGRFAM: excinuclease ABC, A subunit YP_004162616.1 InterPro IPR018060: IPR000005; KEGG: pru:PRU_0411 AraC family transcriptional regulator; PFAM: helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: AraC family transcriptional regulator YP_004162617.1 COGs: COG3119 Arylsulfatase A; InterPro IPR000917; KEGG: pru:PRU_0412 sulfatase; PFAM: sulfatase; SPTR: Sulfatase; PFAM: Sulfatase YP_004162618.1 KEGG: bfs:BF3160 hypothetical protein; SPTR: uncharacterized protein YP_004162619.1 KEGG: bfs:BF3161 hypothetical protein; SPTR: uncharacterized protein YP_004162620.1 COGs: COG1966 Carbon starvation protein predicted membrane protein; InterPro IPR003706; KEGG: bth:BT_1742 carbon starvation protein A; PFAM: carbon starvation protein CstA; SPTR: uncharacterized protein; PFAM: Carbon starvation protein CstA YP_004162621.1 COGs: COG1649 conserved hypothetical protein; InterPro IPR003790; KEGG: bfr:BF3325 hypothetical protein; PFAM: protein of unknown function DUF187; SPTR: uncharacterized protein; PFAM: Uncharacterised BCR, COG1649 YP_004162622.1 KEGG: dmo:Dmoj_GI19101 GI19101 gene product from transcript GI19101-RA; SPTR: GI19101 YP_004162623.1 KEGG: rno:689900 hypothetical protein LOC689900; SPTR: Predicted protein YP_004162624.1 KEGG: pdi:BDI_1003 hypothetical protein; SPTR: uncharacterized protein; TIGRFAM: DNA-binding protein, histone-like YP_004162625.1 KEGG: bfo:BRAFLDRAFT_111358 hypothetical protein; SPTR: uncharacterized protein YP_004162626.1 InterPro IPR005829; KEGG: bth:BT_1745 hypothetical protein; SPTR: uncharacterized protein YP_004162627.1 COGs: COG1373 ATPase (AAA+ superfamily); KEGG: bfs:BF3166 hypothetical protein; SPTR: uncharacterized protein YP_004162628.1 COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterProIPR011895: IPR017900: IPR002880: IPR019752: IPR 019456: IPR011766: IPR017896; KEGG: bth:BT_1747 pyruvate-flavodoxin oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase, catalytic domain; Pyruvate-flavodoxin oxidoreductase, EKR domain; thiamine pyrophosphate TPP-binding domain-containing protein; SPTR: Pyruvate:ferredoxin (Flavodoxin) oxidoreductase; TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: Domain of unknown function; domain; Pyruvate ferredoxin/flavodoxin oxidoreductase; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; TIGRFAM: 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate family; pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric YP_004162629.1 InterPro IPR005902; KEGG: pgn:PGN_1415 DNA-binding protein histone-like family; SPTR: uncharacterized protein; TIGRFAM: DNA-binding protein; TIGRFAM: DNA-binding protein, histone-like YP_004162630.1 COGs: COG0642 Signal transduction histidine kinase; InterPro IPR004358: IPR003661: IPR003594: IPR005467; KEGG: pdi:BDI_0806 two-component system sensor histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: uncharacterized protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain YP_004162631.1 KEGG: afm:AFUA_5G09960 GPI anchored protein; SPTR: uncharacterized protein YP_004162632.1 COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR020449: IPR000005: IPR018060; KEGG: bth:BT_0729 transcriptional regulator; PFAM: helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: uncharacterized protein; PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family YP_004162633.1 COGs: COG0667 oxidoreductase (related to aryl-alcohol dehydrogenase); InterPro IPR020471: IPR001395; KEGG: bfs:BF2134 aldo/keto reductase; PFAM: aldo/keto reductase; SPTR: uncharacterized protein; PFAM: Aldo/keto reductase YP_004162634.1 COGs: COG2159 metal-dependent hydrolase of the TIM-barrel fold; InterPro IPR006992; KEGG: amu:Amuc_1808 amidohydrolase 2; PFAM: amidohydrolase 2; SPTR: Amidohydrolase 2; PFAM: Amidohydrolase YP_004162635.1 InterPro IPR007138; KEGG: pru:PRU_1505 antibiotic biosynthesis monooxygenase; PFAM: Antibiotic biosynthesis monooxygenase; SPTR: uncharacterized protein; PFAM: Antibiotic biosynthesis monooxygenase YP_004162636.1 COGs: COG1853 Conserved protein/domain typically associated with flavoprotein oxygenase DIM6/NTAB family; InterPro IPR002563; KEGG: bfr:BF2074 NADPH-flavin oxidoreductase; PFAM: flavin reductase domain protein FMN-binding; SPTR: Flavoredoxin; PFAM: Flavin reductase like domain YP_004162637.1 COGs: COG0524 Sugar kinase ribokinase; InterPro IPR002173: IPR011611; KEGG: bth:BT_1757 fructokinase; PFAM: PfkB domain protein; SPTR: uncharacterized protein; PFAM: pfkB family carbohydrate kinase YP_004162638.1 COGs: COG0738 Fucose permease; InterPro IPR011701; KEGG: bfs:BF3176 sugar transport-related, membrane protein; PFAM: major facilitator superfamily MFS_1; SPTR: uncharacterized protein; PFAM: Major Facilitator Superfamily YP_004162639.1 COGs: COG1621 Beta-fructosidase (levanase/invertase); InterPro IPR013148: IPR013189: IPR001362; KEGG: bth:BT_1765 levanase precursor (2,6-beta-D-fructofuranosidase); PFAM: glycosyl hydrolase 32; SMART: glycoside hydrolase 32; SPTR: Levanase; PFAM: glycosyl hydrolases family 32 C terminal; glycosyl hydrolases family 32 N-terminal domain YP_004162640.1 COGs: COG4667 esterase of the alpha-beta hydrolase superfamily; InterPro IPR002641; KEGG: bfs:BF3185 phospholipase; PFAM: patatin; SPTR: uncharacterized protein; PFAM: patatin-like phospholipase YP_004162641.1 COGs: COG3579 Aminopeptidase C; InterPro IPR000169: IPR004134; KEGG: bvu:BVU_2072 aminopeptidase C; PFAM: peptidase C1B bleomycin hydrolase; SPTR: Aminopeptidase C; PFAM: peptidase C1-like family YP_004162642.1 COGs: COG0545 FKBP-type peptidyl-prolyl cis-trans isomerase 1; InterPro IPR001179; KEGG: pru:PRU_0972 FKBP family peptidyl-prolyl cis-trans isomerase; PFAM: peptidylprolyl isomerase FKBP-type; SPTR: peptidyl-prolyl cis-trans isomerase; PFAM: FKBP-type peptidyl-prolyl cis-trans isomerase YP_004162643.1 COGs: COG3279 Response regulator of the LytR/AlgR family; InterPro IPR001789: IPR007492; KEGG: bfr:BF3365 two-component system response regulator; PFAM: LytTr DNA-binding region; response regulator receiver; SMART: response regulator receiver; SPTR: Response regulator receiver domain protein; PFAM: Response regulator receiver domain; LytTr DNA-binding domain YP_004162644.1 COGs: COG3275 regulator of cell autolysis; InterPro IPR010559; KEGG: bfr:BF3366 two-component system sensor protein; PFAM: histidine kinase internal region; SPTR: two-component system sensor protein; PFAM: Histidine kinase YP_004162645.1 KEGG: bth:BT_1796 hypothetical protein; SPTR: uncharacterized protein YP_004162646.1 InterPro IPR019619; KEGG: bth:BT_3499 hypothetical protein; PFAM: Protein of unknown function DUF2490; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF2490) YP_004162647.1 KEGG: bth:BT_3498 hypothetical protein; SPTR: uncharacterized protein YP_004162648.1 InterPro IPR018966; KEGG: bth:BT_3497 hypothetical protein; PFAM: VTC domain; SPTR: peptidase aspartic, active site; PFAM: VTC domain YP_004162649.1 COGs: COG2086 Electron transfer flavoprotein beta subunit; InterPro IPR000049: IPR014730; KEGG: bvu:BVU_0325 electron transfer flavoprotein beta-subunit; PFAM: Electron transfer flavoprotein alpha/beta-subunit; SPTR: uncharacterized protein; PFAM: Electron transfer flavoprotein domain YP_004162650.1 COGs: COG2025 Electron transfer flavoprotein alpha subunit; InterPro IPR014730: IPR014731: IPR001308; KEGG: bvu:BVU_0326 electron transfer flavoprotein alpha-subunit; PFAM: Electron transfer flavoprotein alpha subunit; Electron transfer flavoprotein alpha/beta-subunit; SPTR: uncharacterized protein; PFAM: Electron transfer flavoprotein domain; Electron transfer flavoprotein FAD-binding domain YP_004162651.1 KEGG: cpb:Cphamn1_1908 S23 ribosomal protein; SPTR: Intervening sequence, 23S rRNA; PFAM: S23 ribosomal protein YP_004162652.1 COGs: COG1960 Acyl-CoA dehydrogenase; InterPro IPR006089: IPR006092: IPR006091: IPR006090; KEGG: bvu:BVU_0328 acyl-CoA dehydrogenase; PFAM: acyl-CoA dehydrogenase domain-containing protein; SPTR: uncharacterized protein; PFAM: Acyl-CoA dehydrogenase, C-terminal domain; Acyl-CoA dehydrogenase, middle domain; Acyl-CoA dehydrogenase C terminal; Acyl-CoA dehydrogenase, N-terminal domain YP_004162653.1 InterPro IPR000182; KEGG: bth:BT_4696 hypothetical protein; SPTR: uncharacterized protein; PFAM: Acetyltransferase (GNAT) family YP_004162654.1 KEGG: bth:BT_4511 hypothetical protein; SPTR: uncharacterized protein YP_004162655.1 KEGG: bth:BT_2370 hypothetical protein; SPTR: uncharacterized protein YP_004162656.1 InterPro IPR002781; KEGG: lpj:JDM1_2547 transport protein; PFAM: protein of unknown function DUF81; SPTR: Conserved domain protein; PFAM: Sulfite exporter TauE/SafE YP_004162657.1 KEGG: bfr:BF3376 hypothetical protein; SPTR: uncharacterized protein YP_004162658.1 COGs: COG0484 DnaJ-class molecular chaperone with C-terminal Zn finger domain; InterPro IPR003095: IPR018253: IPR001623: IPR002939; KEGG: bth:BT_1812 chaperone DnAJ; PFAM: chaperone DnaJ domain protein; heat shock protein DnaJ domain protein; SMART: heat shock protein DnaJ domain protein; SPTR: uncharacterized protein; PFAM: DnaJ domain; DnaJ C terminal region YP_004162659.1 COGs: COG2008 Threonine aldolase; InterPro IPR001597; KEGG: bfs:BF3212 aldolase; PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase; PRIAM: Threonine aldolase; SPTR: uncharacterized protein; PFAM: Beta-eliminating lyase YP_004162660.1 InterPro IPR019707; KEGG: bfs:BF3216 hypothetical protein; PFAM: Protein of unknown function DUF2582; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF2582) YP_004162661.1 COGs: COG0459 Chaperonin GroEL (HSP60 family); InterPro IPR001844: IPR018370: IPR002423; KEGG: bth:BT_1829 chaperonin GroEL; PFAM: chaperonin Cpn60/TCP-1; SPTR: 60 kDa chaperonin; TIGRFAM: chaperonin GroEL; PFAM: TCP-1/cpn60 chaperonin family; TIGRFAM: chaperonin GroL YP_004162662.1 COGs: COG0234 Co-chaperonin GroES (HSP10); InterPro IPR001476: IPR020818; KEGG: bth:BT_1830 co-chaperonin GroES; PFAM: Chaperonin Cpn10; SPTR: 10 kDa chaperonin; PFAM: Chaperonin 10 Kd subunit YP_004162663.1 InterPro IPR017900: IPR017896; KEGG: bvu:BVU_4056 hypothetical protein; SPTR: uncharacterized protein YP_004162664.1 KEGG: bfr:BF3405 hypothetical protein; SPTR: uncharacterized protein YP_004162665.1 InterPro IPR002931; KEGG: bfs:BF3239 hypothetical protein; PFAM: transglutaminase; SPTR: uncharacterized protein; PFAM: Transglutaminase-like superfamily YP_004162666.1 COGs: COG0124 Histidyl-tRNA synthetase; InterProIPR015807: IPR002314: IPR004154: IPR006195: IPR 004516; KEGG: bth:BT_1840 histidyl-tRNA synthetase; PFAM: tRNA synthetase class II (G H P and S); Anticodon-binding domain protein; PRIAM: Histidine--tRNA ligase; SPTR: Histidyl-tRNA synthetase; TIGRFAM: histidyl-tRNA synthetase; PFAM: Anticodon binding domain; tRNA synthetase class II core domain (G, H, P, S and T); TIGRFAM: histidyl-tRNA synthetase YP_004162667.1 InterPro IPR002931; KEGG: bfs:BF3239 hypothetical protein; PFAM: transglutaminase; SPTR: uncharacterized protein; PFAM: Transglutaminase-like superfamily YP_004162668.1 COGs: COG2738 Zn-dependent protease; InterPro IPR007395; KEGG: bfs:BF3241 hypothetical protein; PFAM: peptidase membrane zinc metallopeptidase; SPTR: uncharacterized protein; PFAM: neutral zinc metallopeptidase YP_004162669.1 COGs: COG3669 alpha-L-fucosidase; InterPro IPR016286: IPR000933; KEGG: bfs:BF3242 exported alpha-L-fucosidase; PFAM: glycoside hydrolase 29 (alpha-L-fucosidase); SMART: glycoside hydrolase 29 (alpha-L-fucosidase); SPTR: uncharacterized protein; PFAM: alpha-L-fucosidase YP_004162670.1 COGs: COG0104 Adenylosuccinate synthase; InterPro IPR001114: IPR018220; KEGG: bfs:BF3243 adenylosuccinate synthetase; PFAM: adenylosuccinate synthetase; PRIAM: Adenylosuccinate synthase; SMART: adenylosuccinate synthetase; SPTR: Adenylosuccinate synthetase; TIGRFAM: adenylosuccinate synthetase; PFAM: Adenylosuccinate synthetase; TIGRFAM: adenylosuccinate synthase YP_004162671.1 COGs: COG0735 Fe2+/Zn2+ uptake regulation protein; InterPro IPR002481; KEGG: bth:BT_1844 transcriptional regulator, iron uptake regulation protein; PFAM: ferric-uptake regulator; SPTR: uncharacterized protein; PFAM: Ferric uptake regulator family YP_004162672.1 KEGG: bth:BT_1845 hypothetical protein; SPTR: uncharacterized protein; PFAM: DNA alkylation repair enzyme YP_004162673.1 InterPro IPR005317; KEGG: bfs:BF3247 membrane attached peptidase; PFAM: peptidase M49; PRIAM: Dipeptidyl-peptidase III; SPTR: uncharacterized protein; PFAM: peptidase M49 YP_004162674.1 COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR000005: IPR018060; KEGG: bfs:BF3248 AraC family transcriptional regulator; PFAM: helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: AraC/XylS family transcriptional regulator YP_004162675.1 COGs: COG0514 Superfamily II DNA helicase; InterProIPR006293: IPR018329: IPR011545: IPR001650: IPR 018982: IPR002121: IPR014001: IPR014021; KEGG: bth:BT_1848 ATP-dependent DNA helicase RecQ; PFAM: RQC domain; DEAD/DEAH box helicase domain protein; helicase domain protein; HRDC domain protein; SMART: helicase domain protein; DEAD-like helicase; HRDC domain protein; SPTR: uncharacterized protein; TIGRFAM: ATP-dependent DNA helicase RecQ; ATP-dependent DNA helicase, RecQ family; PFAM: Helicase conserved C-terminal domain; RQC domain; HRDC domain; DEAD/DEAH box helicase; TIGRFAM: ATP-dependent DNA helicase RecQ; ATP-dependent DNA helicase, RecQ family YP_004162676.1 InterPro IPR001440: IPR019734: IPR013026; KEGG: bfs:BF3250 TPR repeat-containing protein; PFAM: hypothetical protein; SPTR: uncharacterized protein; PFAM: Tetratricopeptide repeat YP_004162677.1 COGs: COG0031 Cysteine synthase; InterPro IPR005856: IPR005859: IPR001216: IPR001926; KEGG: bfs:BF3251 cysteine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; SPTR: Cysteine synthase; TIGRFAM: cysteine synthase; cysteine synthase A; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: cysteine synthase A; cysteine synthases YP_004162678.1 COGs: COG0473 Isocitrate/isopropylmalate dehydrogenase; InterPro IPR004429: IPR019818: IPR001804; KEGG: pdi:BDI_2059 3-isopropylmalate dehydrogenase; PFAM: isocitrate/isopropylmalate dehydrogenase; PRIAM: 3-isopropylmalate dehydrogenase; SPTR: 3-isopropylmalate dehydrogenase; TIGRFAM: 3-isopropylmalate dehydrogenase; PFAM: Isocitrate/isopropylmalate dehydrogenase; TIGRFAM: 3-isopropylmalate dehydrogenase YP_004162679.1 KEGG: mdo:100021661 similar to chromosome 9 open reading frame 61; SPTR: uncharacterized protein YP_004162680.1 COGs: COG0119 Isopropylmalate/homocitrate/citramalate synthase; InterPro IPR002034: IPR000891: IPR013709; KEGG: bvu:BVU_2007 2-isopropylmalate synthase; PFAM: pyruvate carboxyltransferase; LeuA allosteric (dimerisation) domain-containing protein; PRIAM: (R)-citramalate synthase; SPTR: uncharacterized protein; PFAM: HMGL-like; LeuA allosteric (dimerisation) domain YP_004162681.1 COGs: COG0066 3-isopropylmalate dehydratase small subunit; InterPro IPR004431: IPR000573; KEGG: bvu:BVU_2006 3-isopropylmalate dehydratase small subunit; PFAM: aconitate hydratase domain-containing protein; SPTR: uncharacterized protein; TIGRFAM: 3-isopropylmalate dehydratase, small subunit; PFAM: Aconitase C-terminal domain; TIGRFAM: 3-isopropylmalate dehydratase, small subunit YP_004162682.1 COGs: COG0065 3-isopropylmalate dehydratase large subunit; InterPro IPR001030: IPR004430: IPR018136; KEGG: bth:BT_1860 isopropylmalate isomerase large subunit; PFAM: aconitate hydratase domain-containing protein; SPTR: uncharacterized protein; TIGRFAM: 3-isopropylmalate dehydratase, large subunit; PFAM: Aconitase (aconitate hydratase); TIGRFAM: 3-isopropylmalate dehydratase, large subunit YP_004162683.1 COGs: COG0119 Isopropylmalate/homocitrate/citramalate synthase; InterProIPR005671: IPR002034: IPR018278: IPR000891: IPR 013709; KEGG: bth:BT_1861 2-isopropylmalate synthase; PFAM: pyruvate carboxyltransferase; LeuA allosteric (dimerisation) domain-containing protein; SPTR: 2-isopropylmalate synthase; TIGRFAM: 2-isopropylmalate synthase; PFAM: LeuA allosteric (dimerisation) domain; HMGL-like; TIGRFAM: 2-isopropylmalate synthase, bacterial type YP_004162684.1 KEGG: bfs:BF3268 lipoprotein; SPTR: uncharacterized protein YP_004162685.1 COGs: COG0616 Periplasmic serine protease (ClpP class); InterPro IPR004634: IPR004635: IPR002142; KEGG: bth:BT_1879 protease IV; PFAM: peptidase S49; SPTR: uncharacterized protein; TIGRFAM: signal peptide peptidase SppA, 67K type; signal peptide peptidase SppA, 36K type; PFAM: peptidase S49; TIGRFAM: signal peptide peptidase SppA, 36K type; signal peptide peptidase SppA, 67K type YP_004162686.1 COGs: COG1663 Tetraacyldisaccharide-1-P 4'-kinase; InterPro IPR003758; KEGG: bfs:BF3273 tetraacyldisaccharide kinase (lipid A biosynthesis) related protein; PFAM: Tetraacyldisaccharide-1-P 4'-kinase; PRIAM: Tetraacyldisaccharide 4'-kinase; SPTR: Tetraacyldisaccharide 4'-kinase; TIGRFAM: tetraacyldisaccharide 4'-kinase; PFAM: Tetraacyldisaccharide-1-P 4'-kinase; TIGRFAM: tetraacyldisaccharide 4'-kinase YP_004162687.1 COGs: COG0005 Purine nucleoside phosphorylase; InterPro IPR011268: IPR011270: IPR000845; KEGG: bfs:BF3274 purine nucleoside phosphorylase; PFAM: purine or other phosphorylase 1; SPTR: uncharacterized protein; TIGRFAM: inosine guanosine and xanthosine phosphorylase; purine nucleoside phosphorylase I, inosine and guanosine-specific; PFAM: phosphorylase superfamily; TIGRFAM: purine nucleoside phosphorylase I, inosine and guanosine-specific; inosine guanosine and xanthosine phosphorylase YP_004162688.1 COGs: COG0611 Thiamine monophosphate kinase; InterPro IPR006283: IPR000728: IPR010918; KEGG: bth:BT_1882 thiamine-monophosphate kinase; PFAM: AIR synthase related protein; AIR synthase related protein domain protein; PRIAM: Thiamine-phosphate kinase; SPTR: uncharacterized protein; TIGRFAM: thiamine-monophosphate kinase; PFAM: AIR synthase related protein, N-terminal domain; AIR synthase related protein, C-terminal domain; TIGRFAM: thiamine-monophosphate kinase YP_004162689.1 COGs: COG4974 Site-specific recombinase XerD; InterPro IPR002104; KEGG: bfr:BF2058 tyrosine type site-specific recombinase; PFAM: integrase; SPTR: Site-specific recombinase, phage integrase; PFAM: Phage integrase YP_004162690.1 InterPro IPR000425; KEGG: pdi:BDI_0743 hypothetical protein; SPTR: uncharacterized protein YP_004162691.1 KEGG: pdi:BDI_0746 hypothetical protein; SPTR: uncharacterized protein YP_004162692.1 KEGG: pdi:BDI_2234 hypothetical protein; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF3408) YP_004162693.1 InterPro IPR002104; KEGG: pdi:BDI_0750 transposase; PFAM: integrase; SPTR: Site-specific recombinase XerD; PFAM: Phage integrase YP_004162694.1 KEGG: bth:BT_4014 type II restriction endonuclease; SPTR: type II restriction endonuclease YP_004162695.1 InterPro IPR002052: IPR006935: IPR014001: IPR014021; KEGG: bth:BT_4013 restriction endonuclease; PFAM: type III restriction protein res subunit; SMART: DEAD-like helicase; SPTR: Eco57I restriction endonuclease; PFAM: Eco57I restriction endonuclease; type III restriction enzyme, res subunit YP_004162696.1 KEGG: ant:Arnit_2902 hypothetical protein; SPTR: uncharacterized protein; TIGRFAM: conserved hypothetical protein TIGR02646 YP_004162697.1 KEGG: abu:Abu_0110 hypothetical protein; SPTR: uncharacterized protein YP_004162698.1 InterPro IPR001917; KEGG: bfs:BF1101 hypothetical protein; SPTR: uncharacterized protein YP_004162699.1 KEGG: bfs:BF1100 ATP-binding protein; SPTR: uncharacterized protein YP_004162702.1 COGs: COG0225 peptide methionine sulfoxide reductase; InterPro IPR002569; KEGG: bfs:BF3378 bifunctional methionine sulfoxide reductase A/B protein; PFAM: methionine sulfoxide reductase A; PRIAM: peptide-methionine (S)-S-oxide reductase; SPTR: uncharacterized protein; TIGRFAM: peptide methionine sulfoxide reductase; PFAM: peptide methionine sulfoxide reductase; TIGRFAM: methionine-S-sulfoxide reductase YP_004162703.1 COGs: COG1359 conserved hypothetical protein; InterPro IPR007138; KEGG: pdi:BDI_1077 hypothetical protein; PFAM: Antibiotic biosynthesis monooxygenase; SPTR: uncharacterized protein; PFAM: Antibiotic biosynthesis monooxygenase YP_004162704.1 KEGG: bfs:BF2168 hypothetical protein; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF2874) YP_004162705.1 InterPro IPR014127; KEGG: bth:BT_1899 hypothetical protein; PFAM: Conserved hypothetical protein CHP02757; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF2400); TIGRFAM: conserved hypothetical protein TIGR02757 YP_004162706.1 COGs: COG0860 N-acetylmuramoyl-L-alanine amidase; InterPro IPR002508; KEGG: bfs:BF3352 cell wall biosynthesis related protein; PFAM: cell wall hydrolase/autolysin; SPTR: uncharacterized protein; PFAM: N-acetylmuramoyl-L-alanine amidase YP_004162707.1 COGs: COG2873 O-acetylhomoserine sulfhydrylase; InterPro IPR006235: IPR000277; KEGG: bfs:BF3351 cysteine biosynthesis related protein; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; PRIAM: Cysteine synthase; SPTR: uncharacterized protein; TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism PLP-dependent enzyme; TIGRFAM: OAH/OAS sulfhydrylase YP_004162708.1 COGs: COG0281 Malic enzyme; InterPro IPR012301: IPR012302: IPR002505: IPR012188; KEGG: bvu:BVU_0245 malic enzyme; PFAM: malic protein NAD-binding; malic protein domain protein; phosphate acetyl/butaryl transferase; SPTR: uncharacterized protein; PFAM: Malic enzyme, NAD binding domain; phosphate acetyl/butaryl transferase; Malic enzyme, N-terminal domain YP_004162709.1 COGs: COG0334 Glutamate dehydrogenase/leucine dehydrogenase; InterPro IPR006095: IPR006097: IPR006096: IPR014362; KEGG: bvu:BVU_0246 glutamate dehydrogenase; PFAM: Glu/Leu/Phe/Val dehydrogenase; Glu/Leu/Phe/Val dehydrogenase dimerisation region; PRIAM: Glutamate dehydrogenase (NADP(+)); SPTR: uncharacterized protein; PFAM: Glutamate/Leucine/Phenylalanine/Valine dehydrogenase; Glu/Leu/Phe/Val dehydrogenase, dimerisation domain YP_004162710.1 COGs: COG1538 Outer membrane protein; KEGG: sli:Slin_6956 hypothetical protein; SPTR: Predicted protein YP_004162711.1 InterPro IPR006143; KEGG: sli:Slin_6955 hypothetical protein; SPTR: Predicted protein; TIGRFAM: efflux transporter, RND family, MFP subunit; TIGRFAM: RND family efflux transporter, MFP subunit YP_004162712.1 COGs: COG0841 Cation/multidrug efflux pump; InterPro IPR001036; KEGG: sli:Slin_6954 acriflavin resistance protein; PFAM: acriflavin resistance protein; SPTR: Acriflavin resistance protein; PFAM: AcrB/AcrD/AcrF family; TIGRFAM: heavy metal efflux pump (cobalt-zinc-cadmium) YP_004162713.1 COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789: IPR001867; KEGG: cpi:Cpin_4882 two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain-containing protein; SMART: response regulator receiver; SPTR: two-component system response regulator; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal YP_004162714.1 COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661: IPR003594: IPR005467; KEGG: cpi:Cpin_4883 histidine kinase; PFAM: histidine kinase A domain protein; ATP-binding region ATPase domain protein; SMART: histidine kinase A domain protein; ATP-binding region ATPase domain protein; SPTR: Twp-component sensor histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain YP_004162715.1 COGs: COG1629 Outer membrane receptor protein mostly Fe transport; InterPro IPR012910: IPR000531; KEGG: pzu:PHZ_c3264 TonB-dependent receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor plug; SPTR: TonB-dependent receptor domain protein; PFAM: TonB dependent receptor; TonB-dependent Receptor Plug Domain YP_004162716.1 InterPro IPR000326; KEGG: pdi:BDI_0813 hypothetical protein; PFAM: phosphoesterase PA-phosphatase related; SMART: phosphoesterase PA-phosphatase related; SPTR: PAP2 superfamily protein; PFAM: PAP2 superfamily YP_004162717.1 COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR002347: IPR002198; KEGG: amu:Amuc_1001 short chain dehydrogenase; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: Short-chain dehydrogenase/reductase SDR; PFAM: short chain dehydrogenase YP_004162718.1 KEGG: chy:CHY_1707 hypothetical protein; SPTR: uncharacterized protein YP_004162719.1 InterPro IPR000005: IPR018060; KEGG: coc:Coch_1294 AraC family transcriptional regulator; PFAM: helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: AraC family transcriptional regulator; PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family YP_004162720.1 COGs: COG0523 GTPase (G3E family); InterPro IPR003495: IPR011629; KEGG: bvu:BVU_1746 hypothetical protein; PFAM: cobalamin synthesis protein P47K; cobalamin synthesis CobW domain protein; SPTR: uncharacterized protein; PFAM: Cobalamin synthesis protein cobW C-terminal domain; CobW/HypB/UreG, nucleotide-binding domain YP_004162721.1 COGs: COG1057 Nicotinic acid mononucleotide adenylyltransferase; InterPro IPR004821: IPR005248: IPR004820; KEGG: bfs:BF3501 nicotinic acid mononucleotide adenylyltransferase; PFAM: cytidylyltransferase; PRIAM: Nicotinate-nucleotide adenylyltransferase; SPTR: Probable nicotinate-nucleotide adenylyltransferase; TIGRFAM: nicotinate (nicotinamide) nucleotide adenylyltransferase; cytidyltransferase-related domain protein; PFAM: Cytidylyltransferase; TIGRFAM: nicotinate (nicotinamide) nucleotide adenylyltransferase; cytidyltransferase-related domain YP_004162722.1 COGs: COG0194 Guanylate kinase; InterProIPR017665: IPR018073: IPR020590: IPR008144: IPR 008145; KEGG: bvu:BVU_1644 guanylate kinase; PFAM: guanylate kinase; PRIAM: Guanylate kinase; SMART: guanylate kinase/L-type calcium channel region; SPTR: Guanylate kinase; TIGRFAM: guanylate kinase; PFAM: Guanylate kinase; TIGRFAM: guanylate kinase YP_004162723.1 COGs: COG1561 Uncharacterized stress-induced protein; InterPro IPR005229: IPR013527: IPR013551; KEGG: bth:BT_2008 hypothetical protein; PFAM: YicC-like domain-containing protein; domain of unknown function DUF1732; SPTR: uncharacterized protein; PFAM: YicC-like family, N-terminal region; Domain of unknown function (DUF1732); TIGRFAM: conserved hypothetical protein TIGR00255 YP_004162724.1 COGs: COG1214 Inactive homolog of metal-dependent protease molecular chaperone; InterPro IPR000905; KEGG: bfs:BF3497 glycoprotease exported protein; PFAM: peptidase M22 glycoprotease; SPTR: uncharacterized protein; PFAM: glycoprotease; TIGRFAM: universal bacterial protein YeaZ YP_004162725.1 KEGG: bfs:BF3496 hypothetical protein; SPTR: uncharacterized protein YP_004162726.1 COGs: COG0766 UDP-N-acetylglucosamine enolpyruvyl transferase; InterPro IPR005750: IPR001986; KEGG: bfs:BF3495 UDP-N-acetylglucosamine 1-carboxyvinyltransferase; PFAM: EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase); PRIAM: UDP-N-acetylglucosamine 1-carboxyvinyltransferase; SPTR: uncharacterized protein; TIGRFAM: UDP-N-acetylglucosamine 1-carboxyvinyltransferase; PFAM: EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase); TIGRFAM: UDP-N-acetylglucosamine 1-carboxyvinyltransferase YP_004162727.1 KEGG: lsg:lse_1654 hypothetical protein; SPTR: Lin1794 protein YP_004162728.1 COGs: COG0806 RimM protein required for 16S rRNA processing; InterPro IPR011961; KEGG: bfs:BF3494 16S rRNA-processing protein RimM; SPTR: uncharacterized protein; TIGRFAM: 16S rRNA processing protein RimM; PFAM: RimM N-terminal domain; TIGRFAM: 16S rRNA processing protein RimM YP_004162729.1 COGs: COG0739 Membrane protein related to metalloendopeptidase; InterPro IPR016047; KEGG: bfr:BF3700 membrane peptidase; PFAM: peptidase M23; SPTR: uncharacterized protein; PFAM: peptidase M23 YP_004162730.1 COGs: COG0743 1-deoxy-D-xylulose 5-phosphate reductoisomerase; InterPro IPR003821: IPR013512: IPR013644; KEGG: bfs:BF3492 1-deoxy-D-xylulose 5-phosphate reductoisomerase; PFAM: 1-deoxy-D-xylulose 5-phosphate reductoisomerase domain-containing protein; PRIAM: 1-deoxy-D-xylulose-5-phosphate reductoisomerase; SPTR: 1-deoxy-D-xylulose 5-phosphate reductoisomerase; TIGRFAM: 1-deoxy-D-xylulose 5-phosphate reductoisomerase; PFAM: 1-deoxy-D-xylulose 5-phosphate reductoisomerase; 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal; TIGRFAM: 1-deoxy-D-xylulose 5-phosphate reductoisomerase YP_004162731.1 COGs: COG0750 membrane-associated Zn-dependent protease 1; InterPro IPR008915; KEGG: bfs:BF3491 protease; PFAM: peptidase M50; SPTR: uncharacterized protein; PFAM: peptidase M50; TIGRFAM: RIP metalloprotease RseP YP_004162732.1 InterPro IPR010190: IPR000683; KEGG: bth:BT_1979 meso-diaminopimelate D-dehydrogenase; PFAM: oxidoreductase domain protein; SPTR: Diaminopimelate dehydrogenase; TIGRFAM: diaminopimelate dehydrogenase; PFAM: Oxidoreductase, NAD-binding Rossmann fold; TIGRFAM: diaminopimelate dehydrogenase YP_004162733.1 COGs: COG0632 Holliday junction resolvasome DNA-binding subunit; InterPro IPR000085: IPR013849: IPR011114: IPR003583; KEGG: bfs:BF3480 Holliday junction DNA helicase RuvA; PFAM: DNA recombination protein RuvA domain I; RuvA domain protein; SPTR: Holliday junction ATP-dependent DNA helicase ruvA; TIGRFAM: Holliday junction DNA helicase RuvA; manually curated; PFAM: RuvA, C-terminal domain; RuvA N terminal domain; TIGRFAM: Holliday junction DNA helicase, RuvA subunit YP_004162734.1 KEGG: bth:BT_1977 hypothetical protein; SPTR: uncharacterized protein YP_004162735.1 COGs: COG0006 Xaa-Pro aminopeptidase; InterPro IPR000587: IPR000994; KEGG: bfs:BF3438 peptidase; PFAM: peptidase M24; creatinase; SPTR: uncharacterized protein; PFAM: Metallopeptidase M24; Creatinase/Prolidase N-terminal domain YP_004162736.1 COGs: COG4744 conserved hypothetical protein; InterPro IPR018676; KEGG: bvu:BVU_2197 hypothetical protein; PFAM: Protein of unknown function DUF2149; SPTR: uncharacterized protein; PFAM: Uncharacterized conserved protein (DUF2149) YP_004162737.1 COGs: COG0811 Biopolymer transport protein; KEGG: bvu:BVU_2196 integral membrane protein; SPTR: uncharacterized protein; PFAM: MotA/TolQ/ExbB proton channel family; TC 2.C.1.1.1 YP_004162738.1 KEGG: bvu:BVU_2195 hypothetical protein; SPTR: uncharacterized protein YP_004162739.1 COGs: COG1429 Cobalamin biosynthesis protein CobN and related Mg-chelatase; InterPro IPR003672; KEGG: bvu:BVU_2194 protoporphyrin IX magnesium chelatase; PFAM: CobN/magnesium chelatase; PRIAM: Magnesium chelatase; SPTR: Protoporphyrin IX magnesium chelatase; PFAM: CobN/Magnesium Chelatase YP_004162740.1 COGs: COG4771 Outer membrane receptor for ferrienterochelin and colicins; InterPro IPR012910: IPR000531; KEGG: bvu:BVU_2193 TonB-dependent receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor plug; SPTR: uncharacterized protein; PFAM: TonB dependent receptor; TonB-dependent Receptor Plug Domain YP_004162741.1 KEGG: bvu:BVU_2192 hypothetical protein; SPTR: uncharacterized protein YP_004162742.1 KEGG: bvu:BVU_2191 hypothetical protein; SPTR: uncharacterized protein YP_004162743.1 COGs: COG0334 Glutamate dehydrogenase/leucine dehydrogenase; InterPro IPR006095: IPR006097: IPR006096: IPR014362; KEGG: bfs:BF3437 glutamate dehydrogenase; PFAM: Glu/Leu/Phe/Val dehydrogenase; Glu/Leu/Phe/Val dehydrogenase dimerisation region; PRIAM: Glutamate dehydrogenase; SPTR: uncharacterized protein; PFAM: Glutamate/Leucine/Phenylalanine/Valine dehydrogenase; Glu/Leu/Phe/Val dehydrogenase, dimerisation domain YP_004162744.1 KEGG: lmh:LMHCC_2631 glycosyl hydrolase 9; SPTR: glycosyl hydrolase 9 protein; PFAM: glycosyl hydrolase 9; N-terminal ig-like domain of cellulase YP_004162745.1 KEGG: aba:Acid345_2907 YVTN beta-propeller repeat-containing protein; SPTR: YVTN beta-propeller repeat-containing protein; PFAM: Trehalose utilisation YP_004162746.1 KEGG: bfr:BF1988 tyrosine type site-specific recombinase; SPTR: Tyrosine type site-specific recombinase YP_004162747.1 SPTR: uncharacterized protein YP_004162748.1 COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR020449: IPR018062: IPR000005: IPR018060; KEGG: lic:LIC20105 DNA binding protein; PFAM: helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: uncharacterized protein; PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family YP_004162749.1 KEGG: mrb:Mrub_0245 hypothetical protein; SPTR: uncharacterized protein YP_004162750.1 COGs: COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)protein; InterPro IPR006664: IPR006665; KEGG: bfs:BF3556 hypothetical protein; PFAM: OmpA/MotB domain protein; SPTR: peptidoglycan-associated lipoprotein; PFAM: OmpA family YP_004162751.1 KEGG: bth:BT_3148 hypothetical protein; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF1812) YP_004162752.1 KEGG: bfr:BF3847 hypothetical protein; SPTR: uncharacterized protein YP_004162753.1 KEGG: bfr:BF3846 hypothetical protein; SPTR: uncharacterized protein YP_004162754.1 KEGG: cce:Ccel_2338 hypothetical protein; SPTR: The GLUG motif protein family protein YP_004162755.1 InterPro IPR005902; KEGG: pdi:BDI_1732 non-specific DNA-binding protein; SPTR: uncharacterized protein; TIGRFAM: DNA-binding protein; TIGRFAM: DNA-binding protein, histone-like YP_004162756.1 KEGG: pru:PRU_2230 lipoprotein; SPTR: uncharacterized protein; PFAM: IPT/TIG domain YP_004162757.1 InterPro IPR012944; KEGG: pru:PRU_2229 lipoprotein; PFAM: RagB/SusD domain protein; SPTR: uncharacterized protein; manually curated; PFAM: SusD family YP_004162758.1 InterPro IPR012910; KEGG: pru:PRU_2228 hypothetical protein; PFAM: TonB-dependent receptor plug; SPTR: uncharacterized protein; PFAM: TonB-dependent Receptor Plug Domain; TonB dependent receptor YP_004162759.1 InterPro IPR012944; KEGG: pru:PRU_2227 lipoprotein; PFAM: RagB/SusD domain protein; SPTR: uncharacterized protein; PFAM: SusD family YP_004162760.1 InterPro IPR012910: IPR000531; KEGG: pru:PRU_2226 hypothetical protein; PFAM: TonB-dependent receptor plug; TonB-dependent receptor; SPTR: uncharacterized protein; PFAM: TonB-dependent Receptor Plug Domain; TonB dependent receptor YP_004162761.1 InterPro IPR005902; KEGG: pgn:PGN_1415 DNA-binding protein histone-like family; SPTR: uncharacterized protein; TIGRFAM: DNA-binding protein; TIGRFAM: DNA-binding protein, histone-like YP_004162762.1 COGs: COG3325 Chitinase; InterPro IPR001579: IPR001223: IPR011583; KEGG: bvu:BVU_1273 glycoside hydrolase; PFAM: glycoside hydrolase 18; PRIAM: Chitinase; SMART: chitinase II; SPTR: uncharacterized protein; PFAM: Trehalose utilisation; glycosyl hydrolases family 18 YP_004162763.1 COGs: COG0738 Fucose permease; InterPro IPR011701; KEGG: bfs:BF3182 transport-related, membrane protein; PFAM: major facilitator superfamily MFS_1; SPTR: Major facilitator superfamily transporter MFS_1; PFAM: Major Facilitator Superfamily YP_004162764.1 COGs: COG0363 6-phosphogluconolactonase/glucosamine-6-phosphate isomerase/deaminase; InterPro IPR018321: IPR006148; KEGG: ctc:CTC02631 glucosamine-6-phosphate deaminase; PFAM: glucosamine/galactosamine-6-phosphate isomerase; PRIAM: glucosamine-6-phosphate deaminase; SPTR: glucosamine-6-phosphate isomerase; PFAM: glucosamine-6-phosphate isomerases/6-phosphogluconolactonase; TIGRFAM: glucosamine-6-phosphate isomerase YP_004162765.1 COGs: COG1940 Transcriptional regulator/sugar kinase; InterPro IPR000600; KEGG: lmh:LMHCC_2632 ROK family protein; PFAM: ROK family protein; SPTR: ROK family protein; PFAM: ROK family YP_004162766.1 COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358: IPR018062: IPR001345: IPR011110: IPR 011123: IPR003661: IPR003594: IPR001789: IPR000005: IPR018060:I PR005467; KEGG: bth:BT_1734 two-component system sensor histidine kinase/response regulator, hybrid ('one component system'); PFAM: ATP-binding region ATPase domain protein; two component regulator three Y domain-containing protein; two component regulator propeller; histidine kinase A domain protein; response regulator receiver; helix-turn-helix- domain containing protein AraC type; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; Helix-turn-helix, AraC domain; SPTR: uncharacterized protein; PFAM: Y_Y_Y domain; Response regulator receiver domain; two component regulator propeller; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; Bacterial regulatory helix-turn-helix proteins, AraC family YP_004162767.1 InterPro IPR002192: IPR001789; KEGG: bth:BT_1972 phosphoenolpyruvate synthase/pyruvate phosphate dikinase; PFAM: pyruvate phosphate dikinase PEP/pyruvate-binding; SPTR: uncharacterized protein; PFAM: Pyruvate phosphate dikinase, PEP/pyruvate binding domain YP_004162768.1 COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR000005: IPR018060; KEGG: pdi:BDI_2802 transcriptional regulator; PFAM: helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: uncharacterized protein; PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family YP_004162769.1 KEGG: pdi:BDI_2800 hypothetical protein; SPTR: uncharacterized protein YP_004162770.1 KEGG: pdi:BDI_2799 hypothetical protein; SPTR: uncharacterized protein YP_004162771.1 KEGG: pdi:BDI_2798 hypothetical protein; SPTR: uncharacterized protein YP_004162772.1 KEGG: pdi:BDI_2796 hypothetical protein; SPTR: uncharacterized protein YP_004162773.1 KEGG: pdi:BDI_2795 lipoprotein; SPTR: uncharacterized protein YP_004162774.1 KEGG: bfr:BF3627 hypothetical protein; SPTR: uncharacterized protein YP_004162775.1 KEGG: bfs:BF3428 hypothetical protein; SPTR: uncharacterized protein YP_004162776.1 COGs: COG1575 1 4-dihydroxy-2-naphthoate octaprenyltransferase; InterPro IPR004657: IPR000537; KEGG: bfs:BF3503 prenyltransferase; PFAM: UbiA prenyltransferase; SPTR: uncharacterized protein; TIGRFAM: 1,4-dihydroxy-2-naphthoate octaprenyltransferase; manually curated; PFAM: UbiA prenyltransferase; TIGRFAM: 1,4-dihydroxy-2-naphthoate octaprenyltransferase YP_004162777.1 COGs: COG1088 dTDP-D-glucose 4 6-dehydratase; InterPro IPR005888: IPR001509; KEGG: bfs:BF3504 dTDP-glucose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; SPTR: dTDP-glucose 4,6-dehydratase; TIGRFAM: dTDP-glucose 4,6-dehydratase; PFAM: NAD dependent epimerase/dehydratase; TIGRFAM: dTDP-glucose 4,6-dehydratase YP_004162778.1 COGs: COG1209 dTDP-glucose pyrophosphorylase; InterPro IPR005907: IPR005835; KEGG: bth:BT_2017 glucose-1-phosphate thymidylyltransferase; PFAM: Nucleotidyl transferase; SPTR: glucose-1-phosphate thymidylyltransferase; TIGRFAM: glucose-1-phosphate thymidylyltransferase; PFAM: Nucleotidyl transferase; TIGRFAM: glucose-1-phosphate thymidylyltransferase, short form YP_004162779.1 COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358: IPR001440: IPR003661: IPR003594: IPR 019734: IPR005467: IPR013026; KEGG: pdi:BDI_0991 two-component sensor histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; hypothetical protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; Tetratricopeptide repeat; SPTR: Sensor histidine kinase/response regulator; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain YP_004162780.1 COGs: COG0622 phosphoesterase; InterPro IPR000979: IPR004843; KEGG: bfs:BF3506 phosphoesterase; PFAM: metallophosphoesterase; SPTR: phosphoesterase; TIGRFAM: phosphodiesterase, MJ0936 family; TIGRFAM: phosphoesterase, MJ0936 family YP_004162781.1 COGs: COG0855 polyphosphate kinase; InterPro IPR003414: IPR000834; KEGG: bfr:BF3714 polyphosphate kinase; PFAM: polyphosphate kinase; PRIAM: polyphosphate kinase; SPTR: polyphosphate kinase; TIGRFAM: polyphosphate kinase; PFAM: polyphosphate kinase; TIGRFAM: polyphosphate kinase 1 YP_004162782.1 KEGG: bfs:BF3508 hypothetical protein; SPTR: uncharacterized protein; PFAM: phosphate transporter family YP_004162783.1 COGs: COG0617 tRNA nucleotidyltransferase/poly(A) polymerase; InterPro IPR005829: IPR002646: IPR006674: IPR003607; KEGG: bth:BT_1975 tRNA nucleotidyltransferase; PFAM: polynucleotide adenylyltransferase region; metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; SPTR: uncharacterized protein; PFAM: HD domain; poly A polymerase head domain YP_004162784.1 KEGG: bfr:BF3641 hypothetical protein; SPTR: uncharacterized protein; manually curated YP_004162785.1 KEGG: bvu:BVU_1845 hypothetical protein; SPTR: uncharacterized protein YP_004162786.1 KEGG: bvu:BVU_1855 hypothetical protein; SPTR: uncharacterized protein; PFAM: SusD family YP_004162787.1 InterPro IPR012910: IPR000531; KEGG: bvu:BVU_1854 hypothetical protein; PFAM: TonB-dependent receptor plug; TonB-dependent receptor; SPTR: RagA protein; PFAM: TonB dependent receptor; TonB-dependent Receptor Plug Domain YP_004162788.1 InterPro IPR012910: IPR000531; KEGG: bth:BT_2264 outer membrane protein Omp121; PFAM: TonB-dependent receptor plug; TonB-dependent receptor; SPTR: uncharacterized protein; PFAM: TonB-dependent Receptor Plug Domain; TonB dependent receptor YP_004162789.1 KEGG: dfe:Dfer_2717 hypothetical protein; SPTR: uncharacterized protein YP_004162790.1 KEGG: bth:BT_2262 hypothetical protein; SPTR: uncharacterized protein YP_004162791.1 KEGG: bth:BT_2261 hypothetical protein; SPTR: uncharacterized protein YP_004162792.1 COGs: COG0784 FOG: CheY-like receiver; InterPro IPR001789; KEGG: bth:BT_2034 two-component system response regulator; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: uncharacterized protein; PFAM: Response regulator receiver domain YP_004162793.1 COGs: COG0488 ATPase components of ABC transporter with duplicated ATPase domains; InterPro IPR017871: IPR003439: IPR003593; KEGG: bfs:BF3510 ABC transport system, ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: uncharacterized protein; PFAM: ABC transporter YP_004162794.1 COGs: COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3); InterPro IPR013027: IPR000815: IPR004099; KEGG: bth:BT_1542 pyridine nucleotide-disulfide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; SPTR: uncharacterized protein; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain YP_004162795.1 KEGG: bfr:BF3720 hypothetical protein; SPTR: uncharacterized protein YP_004162796.1 COGs: COG0845 Membrane-fusion protein; InterPro IPR006143: IPR000089; KEGG: bfs:BF3511 metal resistance related exported protein; PFAM: biotin/lipoyl attachment domain-containing protein; SPTR: uncharacterized protein; TIGRFAM: efflux transporter, RND family, MFP subunit; TIGRFAM: RND family efflux transporter, MFP subunit YP_004162797.1 COGs: COG3696 silver efflux pump; InterPro IPR001036: IPR004763; KEGG: bfs:BF3512 metal resistance related trasport membrane protein; PFAM: acriflavin resistance protein; SPTR: uncharacterized protein; TIGRFAM: heavy metal efflux pump, CzcA family; PFAM: AcrB/AcrD/AcrF family; TIGRFAM: heavy metal efflux pump (cobalt-zinc-cadmium) YP_004162798.1 COGs: COG1538 Outer membrane protein; InterPro IPR003423; KEGG: bfs:BF3513 puter membrane protein; PFAM: outer membrane efflux protein; SPTR: uncharacterized protein; PFAM: Outer membrane efflux protein YP_004162799.1 COGs: COG0144 tRNA and rRNA cytosine-C5-methylase; InterPro IPR001678; KEGG: bth:BT_2042 tRNA and rRNA cytosine-C5-methylase; PFAM: Fmu (Sun) domain protein; SPTR: uncharacterized protein; PFAM: NOL1/NOP2/sun family YP_004162800.1 COGs: COG4771 Outer membrane receptor for ferrienterochelin and colicins; InterPro IPR012910: IPR000531; KEGG: bvu:BVU_3095 TonB-dependent outer membrane receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor plug; SPTR: uncharacterized protein; PFAM: TonB dependent receptor; TonB-dependent Receptor Plug Domain YP_004162801.1 KEGG: bvu:BVU_3094 hypothetical protein; SPTR: uncharacterized protein; manually curated YP_004162802.1 KEGG: bfs:BF3519 hypothetical protein; SPTR: uncharacterized protein YP_004162803.1 COGs: COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog; InterPro IPR014284: IPR000838: IPR007627: IPR013249; KEGG: bfs:BF3520 RNA polymerase sigma factor; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; SPTR: RNA polymerase sigma factor; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family YP_004162804.1 KEGG: bfs:BF3521 hypothetical protein; SPTR: uncharacterized protein YP_004162805.1 COGs: COG1502 phosphatidylserine/phosphatidylglycerophosphate/ cardiolipin synthase; InterPro IPR001736; KEGG: bfs:BF3522 phospholipid biosynthesis related protein; PFAM: phospholipase D/Transphosphatidylase; SMART: phospholipase D/Transphosphatidylase; SPTR: uncharacterized protein; PFAM: phospholipase D Active site motif YP_004162806.1 COGs: COG0207 Thymidylate synthase; InterPro IPR000398: IPR020940; KEGG: bfs:BF3523 thymidylate synthase; PFAM: thymidylate synthase; PRIAM: Thymidylate synthase; SPTR: Thymidylate synthase; TIGRFAM: thymidylate synthase; PFAM: Thymidylate synthase; TIGRFAM: thymidylate synthase YP_004162807.1 COGs: COG0262 Dihydrofolate reductase; InterPro IPR012259: IPR001796; KEGG: bth:BT_2048 dihydrofolate reductase; PFAM: dihydrofolate reductase region; PRIAM: Dihydrofolate reductase; SPTR: uncharacterized protein; PFAM: Dihydrofolate reductase YP_004162808.1 COGs: COG1522 Transcriptional regulators; InterPro IPR000485: IPR019887: IPR019888; KEGG: bfs:BF3525 AsnC family transcriptional regulator; PFAM: Transcription regulator AsnC-type-like; SMART: Transcription regulator AsnC-type; SPTR: uncharacterized protein; PFAM: AsnC family YP_004162809.1 InterPro IPR019026; KEGG: bfs:BF3526 lipoprotein; PFAM: peptidase M64, IgA; SPTR: uncharacterized protein; PFAM: IgA peptidase M64 YP_004162810.1 InterPro IPR000182; KEGG: bth:BT_2051 hypothetical protein; PFAM: GCN5-related N-acetyltransferase; SPTR: uncharacterized protein; PFAM: Acetyltransferase (GNAT) family YP_004162811.1 InterPro IPR003400; KEGG: bfs:BF3527 hypothetical protein; PFAM: Biopolymer transport protein ExbD/TolR; SPTR: uncharacterized protein; PFAM: Biopolymer transport protein ExbD/TolR YP_004162812.1 InterPro IPR003400; KEGG: bfs:BF3528 hypothetical protein; PFAM: Biopolymer transport protein ExbD/TolR; SPTR: uncharacterized protein; PFAM: Biopolymer transport protein ExbD/TolR YP_004162813.1 KEGG: bth:BT_2054 hypothetical protein; SPTR: uncharacterized protein YP_004162814.1 COGs: COG0811 Biopolymer transport protein; InterPro IPR002898; KEGG: bth:BT_2055 biopolymer transport protein; PFAM: MotA/TolQ/ExbB proton channel; SPTR: uncharacterized protein; PFAM: MotA/TolQ/ExbB proton channel family YP_004162815.1 COGs: COG0084 Mg-dependent DNase; InterPro IPR015991: IPR018228: IPR001130: IPR012278; KEGG: bfs:BF3531 DNAse related protein; PFAM: TatD-related deoxyribonuclease; SPTR: uncharacterized protein; TIGRFAM: hydrolase, TatD family; PFAM: TatD related DNase; TIGRFAM: hydrolase, TatD family YP_004162816.1 KEGG: bfr:BF3744 hypothetical protein; SPTR: uncharacterized protein YP_004162817.1 COGs: COG0142 Geranylgeranyl pyrophosphate synthase; InterPro IPR000092; KEGG: bfs:BF3533 isoprenoid biosynthesis related protein; PFAM: polyprenyl synthetase; SPTR: uncharacterized protein; PFAM: polyprenyl synthetase YP_004162818.1 COGs: COG0810 Periplasmic protein TonB links inner and outer membranes; InterPro IPR003538: IPR006260; KEGG: bth:BT_2059 TonB; PFAM: TonB domain; SPTR: uncharacterized protein; TIGRFAM: TonB family protein; PFAM: Gram-negative bacterial tonB protein; TIGRFAM: TonB family C-terminal domain; TC 2.C.1.1.1 YP_004162819.1 COGs: COG0283 Cytidylate kinase; InterPro IPR003136: IPR011994; KEGG: bfs:BF3535 cytidylate kinase; PFAM: cytidylate kinase region; SPTR: Cytidylate kinase; TIGRFAM: cytidylate kinase; PFAM: Cytidylate kinase; TIGRFAM: cytidylate kinase YP_004162820.1 COGs: COG0761 Penicillin tolerance protein; InterPro IPR003451; KEGG: bfs:BF3536 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; PFAM: LytB protein; PRIAM: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; SPTR: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; TIGRFAM: hydroxymethylbutenyl pyrophosphate reductase; PFAM: LytB protein; TIGRFAM: (E)-4-hydroxy-3-methyl-but-2-enyl pyrophosphate reductase (IPP and DMAPP forming) YP_004162821.1 COGs: COG0205 6-phosphofructokinase; InterPro IPR000023: IPR012828: IPR015912: IPR012003; KEGG: bth:BT_2062 6-phosphofructokinase; PFAM: phosphofructokinase; SPTR: uncharacterized protein; TIGRFAM: 6-phosphofructokinase; PFAM: phosphofructokinase; TIGRFAM: 6-phosphofructokinase YP_004162822.1 COGs: COG0372 Citrate synthase; InterPro IPR002020; KEGG: bvu:BVU_1961 citrate synthase; PFAM: Citrate synthase; SPTR: uncharacterized protein; PFAM: Citrate synthase YP_004162823.1 COGs: COG0538 Isocitrate dehydrogenase; InterPro IPR019818: IPR001804; KEGG: bth:BT_2071 isocitrate dehydrogenase [NADP]; PFAM: isocitrate/isopropylmalate dehydrogenase; PRIAM: Isocitrate dehydrogenase (NADP(+)); SPTR: Isocitrate dehydrogenase [NADP]; PFAM: Isocitrate/isopropylmalate dehydrogenase; TIGRFAM: isocitrate dehydrogenase, NADP-dependent, prokaryotic type YP_004162824.1 COGs: COG1048 Aconitase A; InterPro IPR001030: IPR006248: IPR018136: IPR000573; KEGG: bth:BT_2072 aconitate hydratase; PFAM: aconitate hydratase domain-containing protein; SPTR: Aconitate hydratase; TIGRFAM: aconitate hydratase; PFAM: Aconitase C-terminal domain; Aconitase (aconitate hydratase); TIGRFAM: aconitate hydratase, mitochondrial YP_004162825.1 COGs: COG1112 Superfamily I DNA and RNA helicase and helicase subunits; KEGG: bth:BT_2073 helicase; SPTR: uncharacterized protein; TIGRFAM: DNA helicase YP_004162826.1 COGs: COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities; InterPro IPR004839; KEGG: pdi:BDI_2080 aminotransferase; PFAM: aminotransferase class I and II; SPTR: Aminotransferase, classes I and II; PFAM: Aminotransferase class I and II YP_004162827.1 COGs: COG2873 O-acetylhomoserine sulfhydrylase; InterPro IPR000277; KEGG: bfr:BF0991 O-acetylhomoserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; SPTR: uncharacterized protein; PFAM: Cys/Met metabolism PLP-dependent enzyme YP_004162828.1 COGs: COG0059 Ketol-acid reductoisomerase; InterPro IPR013023: IPR013116: IPR000506; KEGG: pdi:BDI_2069 ketol-acid reductoisomerase; PFAM: Acetohydroxy acid isomeroreductase catalytic domain-containing protein; acetohydroxy acid isomeroreductase; SPTR: uncharacterized protein; TIGRFAM: ketol-acid reductoisomerase; PFAM: Acetohydroxy acid isomeroreductase, catalytic domain; TIGRFAM: ketol-acid reductoisomerase YP_004162829.1 COGs: COG3884 Acyl-ACP thioesterase; InterPro IPR002864; KEGG: bth:BT_2075 acyl-ACP thioesterase; PFAM: acyl-ACP thioesterase; SPTR: uncharacterized protein; PFAM: Acyl-ACP thioesterase YP_004162830.1 COGs: COG0440 Acetolactate synthase small (regulatory) subunit; InterPro IPR004789: IPR002912: IPR019455; KEGG: bfs:BF3549 acetohydroxyacid synthase small subunit; PFAM: Acetolactate synthase, small subunit-like; amino acid-binding ACT domain protein; SPTR: uncharacterized protein; TIGRFAM: acetolactate synthase, small subunit; PFAM: ACT domain; Small subunit of acetolactate synthase; TIGRFAM: acetolactate synthase, small subunit YP_004162831.1 COGs: COG0028 Thiamine pyrophosphate-requiring protein; InterPro IPR012846: IPR012001: IPR012000: IPR011766; KEGG: bfs:BF3550 acetolactate synthase large subunit; PFAM: thiamine pyrophosphate TPP-binding domain-containing protein; thiamine pyrophosphate central domain-containing protein; SPTR: uncharacterized protein; TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: Thiamine pyrophosphate enzyme, central domain; Thiamine pyrophosphate enzyme, N-terminal TPP binding domain; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; TIGRFAM: acetolactate synthase, large subunit, biosynthetic type YP_004162832.1 COGs: COG0129 Dihydroxyacid dehydratase/phosphogluconate dehydratase; InterPro IPR004404: IPR020558: IPR000581; KEGG: bth:BT_2078 dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; PRIAM: Dihydroxy-acid dehydratase; SPTR: uncharacterized protein; TIGRFAM: dihydroxy-acid dehydratase; PFAM: Dehydratase; TIGRFAM: dihydroxy-acid dehydratase YP_004162833.1 COGs: COG1047 FKBP-type peptidyl-prolyl cis-trans isomerase 2; InterPro IPR001179; KEGG: bth:BT_2079 peptidyl-prolyl cis-trans isomerase; PFAM: peptidylprolyl isomerase FKBP-type; SPTR: peptidyl-prolyl cis-trans isomerase; PFAM: FKBP-type peptidyl-prolyl cis-trans isomerase YP_004162834.1 COGs: COG3681 conserved hypothetical protein; InterPro IPR021144: IPR013032; KEGG: bfr:BF3772 inner membrane protein; SPTR: uncharacterized protein; PFAM: Serine dehydratase alpha chain YP_004162835.1 KEGG: bvu:BVU_0249 hypothetical protein; SPTR: uncharacterized protein YP_004162837.1 COGs: COG0082 Chorismate synthase; InterPro IPR000453: IPR020541; KEGG: bfr:BF3792 chorismate synthase; PFAM: chorismate synthase; PRIAM: Chorismate synthase; SPTR: Chorismate synthase; TIGRFAM: chorismate synthase; PFAM: Chorismate synthase; TIGRFAM: chorismate synthase YP_004162838.1 COGs: COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylase; InterPro IPR002933: IPR011650; KEGG: bth:BT_2085 succinyl-diaminopimelate desuccinylase; PFAM: peptidase M20; peptidase dimerisation domain protein; SPTR: uncharacterized protein; PFAM: peptidase M20/M25/M40; peptidase dimerisation domain YP_004162839.1 InterPro IPR000086; KEGG: bfr:BF4292 NUDIX/MutT family protein; PFAM: NUDIX hydrolase; SPTR: uncharacterized protein; PFAM: NUDIX domain YP_004162840.1 COGs: COG0550 Topoisomerase IA; InterProIPR000380: IPR005738: IPR006171: IPR013497: IPR 006154: IPR003601: IPR003602; KEGG: bfr:BF3798 DNA topoisomerase III; PFAM: DNA topoisomerase type IA central domain protein; TOPRIM domain-containing protein; SMART: DNA topoisomerase I DNA-binding; DNA topoisomerase I ATP-binding; Toprim sub domain-containing protein; SPTR: uncharacterized protein; TIGRFAM: DNA topoisomerase III; PFAM: Toprim domain; DNA topoisomerase; TIGRFAM: DNA topoisomerase III, bacteria and conjugative plasmid YP_004162841.1 COGs: COG1884 methylmalonyl-CoA mutase N-terminal domain/subunit; InterPro IPR006098: IPR006159: IPR006099: IPR006158; KEGG: bth:BT_2090 methylmalonyl-CoA mutase; PFAM: methylmalonyl-CoA mutase; cobalamin B12-binding domain protein; PRIAM: methylmalonyl-CoA mutase; SPTR: uncharacterized protein; TIGRFAM: methylmalonyl-CoA mutase, large subunit; PFAM: methylmalonyl-CoA mutase; B12 binding domain; TIGRFAM: methylmalonyl-CoA mutase N-terminal domain; methylmalonyl-CoA mutase C-terminal domain YP_004162842.1 COGs: COG1884 methylmalonyl-CoA mutase N-terminal domain/subunit; InterPro IPR004608: IPR006099; KEGG: bfs:BF3593 methylmalonyl-CoA mutase small subunit; PFAM: methylmalonyl-CoA mutase; PRIAM: methylmalonyl-CoA mutase; SPTR: methylmalonyl-CoA mutase, small subunit; TIGRFAM: methylmalonyl-CoA mutase, beta subunit; PFAM: methylmalonyl-CoA mutase; TIGRFAM: methylmalonyl-CoA mutase N-terminal domain; methylmalonyl-CoA mutase, heterodimeric type, beta chain YP_004162843.1 COGs: COG2985 permease; InterPro IPR006512: IPR006037; KEGG: bth:BT_2092 hypothetical protein; PFAM: YidE/YbjL duplication domain-containing protein; TrkA-C domain protein; SPTR: uncharacterized protein; TIGRFAM: YidE/YbjL duplication; PFAM: Predicted Permease Membrane Region; TrkA-C domain; TIGRFAM: AspT/YidE/YbjL antiporter duplication domain YP_004162844.1 KEGG: bfs:BF3595 hypothetical protein; SPTR: uncharacterized protein YP_004162845.1 COGs: COG0534 Na+-driven multidrug efflux pump; InterPro IPR002528; KEGG: bfs:BF3601 cation transport related membrane protein; PFAM: multi antimicrobial extrusion protein MatE; SPTR: uncharacterized protein; TIGRFAM: MATE efflux family protein; PFAM: MatE; TIGRFAM: efflux protein, MATE family YP_004162846.1 COGs: COG1190 Lysyl-tRNA synthetase (class II); InterProIPR018149: IPR002313: IPR004365: IPR004364: IPR 006195; KEGG: bth:BT_2122 lysyl-tRNA synthetase; PFAM: tRNA synthetase class II (D K and N); nucleic acid binding OB-fold tRNA/helicase-type; SPTR: Lysyl-tRNA synthetase; TIGRFAM: lysyl-tRNA synthetase; PFAM: tRNA synthetases class II (D, K and N); OB-fold nucleic acid binding domain; TIGRFAM: lysyl-tRNA synthetase, eukaryotic and non-spirochete bacterial YP_004162847.1 COGs: COG0240 glycerol-3-phosphate dehydrogenase; InterPro IPR006168: IPR011128: IPR006109; KEGG: bth:BT_2123 glycerol-3-phosphate dehydrogenase; PFAM: NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; PRIAM: glycerol-3-phosphate dehydrogenase (NAD(P)(+)); SPTR: glycerol-3-phosphate dehydrogenase; PFAM: NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus YP_004162848.1 COGs: COG0166 glucose-6-phosphate isomerase; InterPro IPR001672: IPR018189; KEGG: bfs:BF3604 glucose-6-phosphate isomerase; PFAM: phosphoglucose isomerase (PGI); PRIAM: glucose-6-phosphate isomerase; SPTR: glucose-6-phosphate isomerase; PFAM: phosphoglucose isomerase YP_004162849.1 COGs: COG0637 phosphatase/phosphohexomutase; InterPro IPR005833: IPR006402: IPR005834; KEGG: bfr:BF3814 beta-phosphoglucomutase; PFAM: Haloacid dehalogenase domain protein hydrolase; SPTR: uncharacterized protein; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED YP_004162850.1 COGs: COG2502 Asparagine synthetase A; InterPro IPR004618: IPR006195; KEGG: bfs:BF3607 asparagine synthetase AsnA; PFAM: aspartate--ammonia ligase; PRIAM: Aspartate--ammonia ligase; SPTR: Aspartate-ammonia ligase; TIGRFAM: aspartate/ammonia ligase; PFAM: Aspartate-ammonia ligase; TIGRFAM: aspartate--ammonia ligase, AsnA-type YP_004162851.1 COGs: COG0692 uracil DNA glycosylase; InterPro IPR002043: IPR018085: IPR005122; KEGG: bth:BT_2130 uracil-DNA glycosylase; PFAM: uracil-DNA glycosylase superfamily; SPTR: uracil-DNA glycosylase; TIGRFAM: uracil-DNA glycosylase; PFAM: uracil DNA glycosylase superfamily; TIGRFAM: uracil-DNA glycosylase YP_004162852.1 COGs: COG1452 Organic solvent tolerance protein OstA; KEGG: bfs:BF3609 hypothetical protein; SPTR: uncharacterized protein YP_004162853.1 InterPro IPR006675: IPR006674; KEGG: bvu:BVU_4150 hypothetical protein; PFAM: metal-dependent phosphohydrolase HD sub domain; SPTR: uncharacterized protein; TIGRFAM: metal dependent phophohydrolase; PFAM: HD domain; TIGRFAM: uncharacterized domain HDIG YP_004162854.1 COGs: COG0726 xylanase/chitin deacetylase; InterPro IPR002509; KEGG: pru:PRU_2902 polysaccharide deacetylase domain-containing protein; PFAM: polysaccharide deacetylase; SPTR: polysaccharide deacetylase; PFAM: Domain of unknown function (DUF3473); polysaccharide deacetylase YP_004162855.1 COGs: COG0463 glycosyltransferase involved in cell wall biogenesis; InterPro IPR001173; KEGG: csc:Csac_1057 ribonuclease III; PFAM: glycosyl transferase 2; SPTR: glycosyl transferase, group 2 family; PFAM: glycosyl transferase 2 YP_004162856.1 InterPro IPR007267; KEGG: bth:BT_3390 hypothetical protein; PFAM: GtrA family protein; SPTR: membrane protein; PFAM: GtrA-like protein YP_004162857.1 KEGG: bth:BT_1588 hypothetical protein; SPTR: uncharacterized protein YP_004162858.1 KEGG: pdi:BDI_0245 sodium-dependent transporter; SPTR: uncharacterized protein YP_004162859.1 COGs: COG0860 N-acetylmuramoyl-L-alanine amidase; InterPro IPR002508; KEGG: bth:BT_2141 N-acetylmuramoyl-L-alanine amidase AmiA; PFAM: cell wall hydrolase/autolysin; SMART: cell wall hydrolase/autolysin; SPTR: uncharacterized protein; manually curated; PFAM: N-acetylmuramoyl-L-alanine amidase YP_004162860.1 COGs: COG1463 ABC-type transport system involved in resistance to organic solvents periplasmic component; InterPro IPR003399; KEGG: bfs:BF3616 hypothetical protein; PFAM: Mammalian cell entry related domain protein; SPTR: uncharacterized protein; PFAM: mce related protein