-- dump date   	20140618_211811
-- class       	Genbank::misc_feature
-- table       	misc_feature_note
-- id	note
1034836000001	chromosomal replication initiation protein; Reviewed; Region: dnaA; PRK00149
1034836000002	DnaA N-terminal domain; Region: DnaA_N; pfam11638
1034836000003	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1034836000004	Walker A motif; other site
1034836000005	ATP binding site [chemical binding]; other site
1034836000006	Walker B motif; other site
1034836000007	arginine finger; other site
1034836000008	C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571
1034836000009	DnaA box-binding interface [nucleotide binding]; other site
1034836000010	DNA polymerase III subunit beta; Validated; Region: PRK05643
1034836000011	Beta clamp domain.  The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria.  The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cd00140
1034836000012	putative DNA binding surface [nucleotide binding]; other site
1034836000013	dimer interface [polypeptide binding]; other site
1034836000014	beta-clamp/clamp loader binding surface; other site
1034836000015	beta-clamp/translesion DNA polymerase binding surface; other site
1034836000016	S4 domain; Region: S4_2; pfam13275
1034836000017	recombination protein F; Reviewed; Region: recF; PRK00064
1034836000018	ATP-binding cassette domain of RecF; Region: ABC_RecF; cd03242
1034836000019	Walker A/P-loop; other site
1034836000020	ATP binding site [chemical binding]; other site
1034836000021	Q-loop/lid; other site
1034836000022	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1034836000023	ABC transporter signature motif; other site
1034836000024	Walker B; other site
1034836000025	D-loop; other site
1034836000026	H-loop/switch region; other site
1034836000027	DNA gyrase subunit B; Validated; Region: gyrB; PRK05644
1034836000028	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1034836000029	ATP binding site [chemical binding]; other site
1034836000030	Mg2+ binding site [ion binding]; other site
1034836000031	G-X-G motif; other site
1034836000032	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
1034836000033	anchoring element; other site
1034836000034	dimer interface [polypeptide binding]; other site
1034836000035	ATP binding site [chemical binding]; other site
1034836000036	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
1034836000037	active site
1034836000038	putative metal-binding site [ion binding]; other site
1034836000039	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
1034836000040	DNA gyrase subunit A; Validated; Region: PRK05560
1034836000041	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
1034836000042	CAP-like domain; other site
1034836000043	active site
1034836000044	primary dimer interface [polypeptide binding]; other site
1034836000045	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1034836000046	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1034836000047	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1034836000048	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1034836000049	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1034836000050	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1034836000051	YaaC-like Protein; Region: YaaC; pfam14175
1034836000052	inosine 5'-monophosphate dehydrogenase; Reviewed; Region: PRK05567
1034836000053	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
1034836000054	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the inosine 5' monophosphate dehydrogenase (IMPDH) protein.  IMPDH is an essential enzyme that catalyzes the first step unique to GTP synthesis, playing a...; Region: CBS_pair_IMPDH; cd04601
1034836000055	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
1034836000056	active site
1034836000057	D-alanyl-D-alanine carboxypeptidase [Cell envelope biogenesis, outer membrane]; Region: DacC; COG1686
1034836000058	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
1034836000059	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; smart00936
1034836000060	pyridoxal 5'-phosphate synthase, synthase subunit Pdx1; Region: TIGR00343
1034836000061	PdxS is a subunit of the pyridoxal 5'-phosphate (PLP) synthase, an important enzyme in deoxyxylulose 5-phosphate (DXP)-independent pathway for de novo biosynthesis of PLP,  present in some eubacteria, in archaea, fungi, plants, plasmodia, and some...; Region: pdxS; cd04727
1034836000062	active site
1034836000063	multimer interface [polypeptide binding]; other site
1034836000064	Glutamine Amidotransferase (GATase_I) involved in pyridoxine biosynthesis; Region: GATase1_PB; cd01749
1034836000065	Glutamine amidotransferase class-I; Region: GATase; pfam00117
1034836000066	predicted active site [active]
1034836000067	catalytic triad [active]
1034836000068	seryl-tRNA synthetase; Provisional; Region: PRK05431
1034836000069	Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403
1034836000070	Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme...; Region: SerRS_core; cd00770
1034836000071	dimer interface [polypeptide binding]; other site
1034836000072	active site
1034836000073	motif 1; other site
1034836000074	motif 2; other site
1034836000075	motif 3; other site
1034836000076	Glycerate kinase [Carbohydrate transport and metabolism]; Region: COG1929
1034836000077	Deoxynucleoside kinases [Nucleotide transport and metabolism]; Region: COG1428
1034836000078	Deoxyribonucleoside kinase (dNK) catalyzes the phosphorylation of deoxyribonucleosides to yield corresponding monophosphates (dNMPs). This family consists of various deoxynucleoside kinases including deoxyribo- cytidine (EC 2.7.1.74), guanosine (EC 2.7.1; Region: dNK; cd01673
1034836000079	Substrate-binding site [chemical binding]; other site
1034836000080	Substrate specificity [chemical binding]; other site
1034836000081	Deoxynucleoside kinases [Nucleotide transport and metabolism]; Region: COG1428
1034836000082	Deoxyribonucleoside kinase (dNK) catalyzes the phosphorylation of deoxyribonucleosides to yield corresponding monophosphates (dNMPs). This family consists of various deoxynucleoside kinases including deoxyribo- cytidine (EC 2.7.1.74), guanosine (EC 2.7.1; Region: dNK; cd01673
1034836000083	Substrate-binding site [chemical binding]; other site
1034836000084	Substrate specificity [chemical binding]; other site
1034836000085	Predicted glycosyl hydrolase [General function prediction only]; Region: COG3858
1034836000086	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1034836000087	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1034836000088	Cortical fragment-lytic enzyme (CFLE) is a peptidoglycan hydrolase involved in  bacterial endospore germination.  CFLE is expressed as an inactive preprotein (called SleB) in the forespore compartment of sporulating cells.  SleB translocates across the...; Region: GH18_CFLE_spore_hydrolase; cd02874
1034836000089	active site
1034836000090	Isochorismatase family; Region: Isochorismatase; pfam00857
1034836000091	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cd00431
1034836000092	catalytic triad [active]
1034836000093	conserved cis-peptide bond; other site
1034836000094	Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285
1034836000095	nucleoside/Zn binding site; other site
1034836000096	dimer interface [polypeptide binding]; other site
1034836000097	catalytic motif [active]
1034836000098	DNA polymerase III subunits gamma and tau; Validated; Region: PRK05563
1034836000099	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1034836000100	Walker A motif; other site
1034836000101	ATP binding site [chemical binding]; other site
1034836000102	Walker B motif; other site
1034836000103	arginine finger; other site
1034836000104	DNA polymerase III subunits gamma and tau domain III; Region: DNA_pol3_gamma3; pfam12169
1034836000105	hypothetical protein; Validated; Region: PRK00153
1034836000106	recombination protein RecR; Reviewed; Region: recR; PRK00076
1034836000107	RecR protein; Region: RecR; pfam02132
1034836000108	TOPRIM_recR: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in Escherichia coli RecR.  RecR participates in the RecFOR pathway of homologous recombinational repair in prokaryotes. This pathway provides a...; Region: TOPRIM_recR; cd01025
1034836000109	putative active site [active]
1034836000110	putative metal-binding site [ion binding]; other site
1034836000111	tetramer interface [polypeptide binding]; other site
1034836000112	Protein of unknown function (DUF2508); Region: DUF2508; pfam10704
1034836000113	SigmaK-factor processing regulatory protein BofA; Region: BofA; pfam07441
1034836000114	Inhibitor of sigma-G Gin; Region: Gin; pfam10764
1034836000115	5-bromo-4-chloroindolyl phosphate hydrolysis protein; Region: Halogen_Hydrol; pfam10112
1034836000116	Toxic anion resistance protein (TelA); Region: TelA; pfam05816
1034836000117	Arginine/lysine/ornithine decarboxylases [Amino acid transport and metabolism]; Region: LdcC; COG1982
1034836000118	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
1034836000119	homodimer interface [polypeptide binding]; other site
1034836000120	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1034836000121	catalytic residue [active]
1034836000122	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
1034836000123	thymidylate kinase; Validated; Region: tmk; PRK00698
1034836000124	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
1034836000125	TMP-binding site; other site
1034836000126	ATP-binding site [chemical binding]; other site
1034836000127	Protein of unknown function (DUF970); Region: DUF970; pfam06153
1034836000128	Protein of unknown function (DUF327); Region: DUF327; pfam03885
1034836000129	DNA polymerase III subunit delta'; Validated; Region: PRK08058
1034836000130	DNA polymerase III subunit delta'; Validated; Region: PRK08485
1034836000131	Uncharacterized homolog of PSP1 [Function unknown]; Region: COG1774
1034836000132	DNA replication intiation control protein YabA; Reviewed; Region: PRK13169
1034836000133	Predicted O-methyltransferase [General function prediction only]; Region: COG4123
1034836000134	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1034836000135	S-adenosylmethionine binding site [chemical binding]; other site
1034836000136	The GIY-YIG domain of uncharacterized protein family UPF0213 related to structure-specific endonuclease SLX1; Region: GIY-YIG_UPF0213; cd10456
1034836000137	GIY-YIG motif/motif A; other site
1034836000138	putative active site [active]
1034836000139	putative metal binding site [ion binding]; other site
1034836000140	Predicted methyltransferases [General function prediction only]; Region: COG0313
1034836000141	Ribosomal RNA small subunit methyltransferase I, also known as rRNA (cytidine-2'-O-)-methyltransferase RsmI; Region: RsmI; cd11648
1034836000142	putative SAM binding site [chemical binding]; other site
1034836000143	putative homodimer interface [polypeptide binding]; other site
1034836000144	Regulators of stationary/sporulation gene expression [Transcription]; Region: AbrB; COG2002
1034836000145	SpoVT / AbrB like domain; Region: SpoVT_AbrB; smart00966
1034836000146	methionyl-tRNA synthetase; Reviewed; Region: PRK12267
1034836000147	catalytic core domain of methioninyl-tRNA synthetases; Region: MetRS_core; cd00814
1034836000148	active site
1034836000149	HIGH motif; other site
1034836000150	KMSKS motif; other site
1034836000151	Anticodon-binding domain of methionyl tRNA synthetases; Region: Anticodon_Ia_Met; cd07957
1034836000152	tRNA binding surface [nucleotide binding]; other site
1034836000153	anticodon binding site; other site
1034836000154	tRNA-binding-domain-containing Escherichia coli methionyl-tRNA synthetase (EcMetRS)-like proteins.  This family includes EcMetRS and Aquifex aeolicus Trbp111 (AaTrbp111). This domain has general tRNA binding properties.  MetRS aminoacylates methionine...; Region: tRNA_bind_EcMetRS_like; cd02800
1034836000155	dimer interface [polypeptide binding]; other site
1034836000156	putative tRNA-binding site [nucleotide binding]; other site
1034836000157	Predicted metal-dependent hydrolases with the TIM-barrel fold [General function prediction only]; Region: COG1099
1034836000158	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
1034836000159	active site
1034836000160	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3583
1034836000161	Domain of unknown function (DUF348); Region: DUF348; pfam03990
1034836000162	Domain of unknown function (DUF348); Region: DUF348; pfam03990
1034836000163	Domain of unknown function (DUF348); Region: DUF348; pfam03990
1034836000164	G5 domain; Region: G5; pfam07501
1034836000165	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3584
1034836000166	ribonuclease M5; Region: 5S_RNA_mat_M5; TIGR00334
1034836000167	TOPRIM_ RNase M5_like: The topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain found in Ribonuclease M5: (RNase M5) and other small primase-like proteins from bacteria and archaea.  RNase M5 catalyzes the maturation of 5S rRNA in low...; Region: TOPRIM_RNase_M5_like; cd01027
1034836000168	putative active site [active]
1034836000169	putative metal binding site [ion binding]; other site
1034836000170	Domain of unknown function (DUF4093); Region: DUF4093; pfam13331
1034836000171	16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Reviewed; Region: ksgA; PRK00274
1034836000172	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1034836000173	S-adenosylmethionine binding site [chemical binding]; other site
1034836000174	sporulation peptidase YabG; Region: spore_yabG; TIGR02855
1034836000175	Protein of unknown function (DUF1021); Region: DUF1021; pfam06257
1034836000176	Small, acid-soluble spore proteins, alpha/beta type; Region: SASP; pfam00269
1034836000177	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Provisional; Region: ipk; PRK00128
1034836000178	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
1034836000179	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
1034836000180	pur operon repressor; Provisional; Region: PRK09213
1034836000181	Bacterial purine repressor, N-terminal; Region: PuR_N; pfam09182
1034836000182	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1034836000183	active site
1034836000184	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
1034836000185	homotrimer interaction site [polypeptide binding]; other site
1034836000186	putative active site [active]
1034836000187	regulatory protein SpoVG; Reviewed; Region: PRK13259
1034836000188	bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase; Provisional; Region: glmU; PRK14354
1034836000189	N-terminal domain of bacterial GlmU; Region: GT2_GlmU_N_bac; cd02540
1034836000190	Substrate binding site; other site
1034836000191	Mg++ binding site; other site
1034836000192	N-acetyl-glucosamine-1-phosphate uridyltransferase (GlmU), C-terminal left-handed beta-helix (LbH) acetyltransferase domain: GlmU is also known as UDP-N-acetylglucosamine pyrophosphorylase. It is a bifunctional bacterial enzyme that catalyzes two...; Region: LbH_GlmU_C; cd03353
1034836000193	active site
1034836000194	substrate binding site [chemical binding]; other site
1034836000195	CoA binding site [chemical binding]; other site
1034836000196	ribose-phosphate pyrophosphokinase; Provisional; Region: PRK01259
1034836000197	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
1034836000198	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1034836000199	active site
1034836000200	50S ribosomal protein L25/general stress protein Ctc; Reviewed; Region: PRK05618
1034836000201	Ribosomal L25/TL5/CTC N-terminal 5S rRNA binding domain; Region: Ribosomal_L25_TL5_CTC; cd00495
1034836000202	5S rRNA interface [nucleotide binding]; other site
1034836000203	CTC domain interface [polypeptide binding]; other site
1034836000204	L16 interface [polypeptide binding]; other site
1034836000205	Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462
1034836000206	putative active site [active]
1034836000207	catalytic residue [active]
1034836000208	Protein of unknown function (DUF2757); Region: DUF2757; pfam10955
1034836000209	Transcription-repair coupling factor (superfamily II helicase) [DNA replication, recombination, and repair / Transcription]; Region: Mfd; COG1197
1034836000210	CarD-like/TRCF domain; Region: CarD_CdnL_TRCF; pfam02559
1034836000211	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1034836000212	ATP binding site [chemical binding]; other site
1034836000213	putative Mg++ binding site [ion binding]; other site
1034836000214	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1034836000215	nucleotide binding region [chemical binding]; other site
1034836000216	ATP-binding site [chemical binding]; other site
1034836000217	This domain is found in proteins necessary for strand-specific repair in DNA such as TRCF in Escherichia coli; Region: TRCF; smart00982
1034836000218	stage V sporulation protein T; Region: spore_V_T; TIGR02851
1034836000219	looped-hinge helix DNA binding domain, AbrB family; Region: lp_hng_hel_AbrB; TIGR01439
1034836000220	Stage V sporulation protein B, also known as Stage III sporulation protein F, and related proteins; Region: MATE_SpoVB_like; cd13124
1034836000221	Protein containing tetrapyrrole methyltransferase domain and MazG-like (predicted pyrophosphatase) domain [General function prediction only]; Region: COG3956
1034836000222	N-terminal S-AdoMet dependent methylase domain of Bacillus subtilis YabN and related proteins; Region: YabN_N; cd11723
1034836000223	putative SAM binding site [chemical binding]; other site
1034836000224	putative homodimer interface [polypeptide binding]; other site
1034836000225	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) N-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs; Region: NTP-PPase_MazG_Nterm; cd11528
1034836000226	homodimer interface [polypeptide binding]; other site
1034836000227	metal binding site [ion binding]; metal-binding site
1034836000228	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) C-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs' Region: NTP-PPase_MazG_Cterm; cd11529
1034836000229	homodimer interface [polypeptide binding]; other site
1034836000230	active site
1034836000231	putative chemical substrate binding site [chemical binding]; other site
1034836000232	metal binding site [ion binding]; metal-binding site
1034836000233	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1034836000234	RNA binding surface [nucleotide binding]; other site
1034836000235	sporulation protein YabP; Region: spore_yabP; TIGR02892
1034836000236	spore cortex biosynthesis protein YabQ; Region: spore_yabQ; TIGR02893
1034836000237	Septum formation initiator [Cell division and chromosome partitioning]; Region: COG2919
1034836000238	Septum formation initiator; Region: DivIC; pfam04977
1034836000239	hypothetical protein; Provisional; Region: PRK08582
1034836000240	S1_RPS1_repeat_hs4: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_hs4; cd05692
1034836000241	RNA binding site [nucleotide binding]; other site
1034836000242	stage II sporulation protein E; Region: spore_II_E; TIGR02865
1034836000243	Stage II sporulation protein E (SpoIIE); Region: SpoIIE; pfam07228
1034836000244	Uncharacterized protein containing a von Willebrand factor type A (vWA) domain [General function prediction only]; Region: COG2304
1034836000245	von Willebrand factor (vWF) type A domain; Region: VWA; smart00327
1034836000246	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cd00198
1034836000247	metal ion-dependent adhesion site (MIDAS); other site
1034836000248	Serine/threonine protein kinase [General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair]; Region: SPS1; COG0515
1034836000249	Protein Kinases, catalytic domain; Region: PKc_like; cl09925
1034836000250	active site
1034836000251	ATP binding site [chemical binding]; other site
1034836000252	substrate binding site [chemical binding]; other site
1034836000253	tRNA(Ile)-lysidine synthase MesJ [Cell cycle control, cell division, chromosome partitioning]; Region: MesJ; COG0037
1034836000254	N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases...; Region: PP-ATPase; cd01992
1034836000255	Ligand Binding Site [chemical binding]; other site
1034836000256	TilS substrate C-terminal domain; Region: TilS_C; smart00977
1034836000257	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1034836000258	active site
1034836000259	FtsH Extracellular; Region: FtsH_ext; pfam06480
1034836000260	ATP-dependent metalloprotease FtsH; Region: FtsH_fam; TIGR01241
1034836000261	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1034836000262	Walker A motif; other site
1034836000263	ATP binding site [chemical binding]; other site
1034836000264	Walker B motif; other site
1034836000265	arginine finger; other site
1034836000266	Peptidase family M41; Region: Peptidase_M41; pfam01434
1034836000267	pantothenate kinase; Reviewed; Region: PRK13318
1034836000268	Hsp33-like chaperonin; Reviewed; Region: hslO; PRK00114
1034836000269	Heat shock protein 33 (Hsp33):  Cytosolic protein that acts as a molecular chaperone under oxidative conditions.  In normal (reducing) cytosolic conditions, four conserved Cys residues are coordinated by a Zn ion. Under oxidative stress (such as heat...; Region: Hsp33; cd00498
1034836000270	dimerization interface [polypeptide binding]; other site
1034836000271	domain crossover interface; other site
1034836000272	redox-dependent activation switch; other site
1034836000273	peptidylprolyl isomerase; Provisional; Region: prsA; PRK00059
1034836000274	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
1034836000275	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
1034836000276	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
1034836000277	dimer interface [polypeptide binding]; other site
1034836000278	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1034836000279	catalytic residue [active]
1034836000280	Anthranilate/para-aminobenzoate synthases component I [Amino acid transport and metabolism / Coenzyme metabolism]; Region: TrpE; COG0147
1034836000281	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
1034836000282	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
1034836000283	para-aminobenzoate synthase component II; Provisional; Region: PRK08857
1034836000284	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
1034836000285	glutamine binding [chemical binding]; other site
1034836000286	catalytic triad [active]
1034836000287	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
1034836000288	ADCL_like: 4-Amino-4-deoxychorismate lyase:  is a member of the fold-type IV of PLP dependent enzymes that converts 4-amino-4-deoxychorismate (ADC) to p-aminobenzoate and pyruvate.  Based on the information available from the crystal structure, most...; Region: ADCL_like; cd01559
1034836000289	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1034836000290	catalytic residue [active]
1034836000291	DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and...; Region: DHPS; cd00739
1034836000292	dihydropteroate synthase; Region: DHPS; TIGR01496
1034836000293	substrate binding pocket [chemical binding]; other site
1034836000294	dimer interface [polypeptide binding]; other site
1034836000295	inhibitor binding site; inhibition site
1034836000296	Dihydroneopterin aldolase (DHNA) and 7,8-dihydroneopterin triphosphate epimerase domain (DHNTPE); these enzymes have been designated folB and folX, respectively. Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and...; Region: DHNA_DHNTPE; cd00534
1034836000297	homooctamer interface [polypeptide binding]; other site
1034836000298	active site
1034836000299	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after...; Region: HPPK; cd00483
1034836000300	catalytic center binding site [active]
1034836000301	ATP binding site [chemical binding]; other site
1034836000302	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1034836000303	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1034836000304	non-specific DNA binding site [nucleotide binding]; other site
1034836000305	salt bridge; other site
1034836000306	sequence-specific DNA binding site [nucleotide binding]; other site
1034836000307	putative TIM-barrel protein, nifR3 family; Region: nifR3_yhdG; TIGR00737
1034836000308	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
1034836000309	FMN binding site [chemical binding]; other site
1034836000310	active site
1034836000311	catalytic residues [active]
1034836000312	substrate binding site [chemical binding]; other site
1034836000313	lysyl-tRNA synthetase; Reviewed; Region: lysS; PRK00484
1034836000314	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
1034836000315	dimer interface [polypeptide binding]; other site
1034836000316	putative anticodon binding site; other site
1034836000317	Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775
1034836000318	motif 1; other site
1034836000319	active site
1034836000320	motif 2; other site
1034836000321	motif 3; other site
1034836000322	Firmicute transcriptional repressor of class III stress genes (CtsR); Region: CtsR; pfam05848
1034836000323	Modulator of heat shock repressor CtsR, McsA [Signal transduction    mechanisms]; Region: COG3880
1034836000324	UvrB/uvrC motif; Region: UVR; pfam02151
1034836000325	ATP:guanido phosphotransferase; Provisional; Region: PRK01059
1034836000326	Phosphagen (guanidino) kinases found in bacteria; Region: bacterial_phosphagen_kinase; cd07930
1034836000327	ADP binding site [chemical binding]; other site
1034836000328	phosphagen binding site; other site
1034836000329	substrate specificity loop; other site
1034836000330	ATP-binding subunits of Clp protease and DnaK/DnaJ chaperones [Posttranslational modification, protein turnover, chaperones]; Region: clpA; COG0542
1034836000331	Clp amino terminal domain; Region: Clp_N; pfam02861
1034836000332	Clp amino terminal domain; Region: Clp_N; pfam02861
1034836000333	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1034836000334	Walker A motif; other site
1034836000335	ATP binding site [chemical binding]; other site
1034836000336	Walker B motif; other site
1034836000337	arginine finger; other site
1034836000338	UvrB/uvrC motif; Region: UVR; pfam02151
1034836000339	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1034836000340	Walker A motif; other site
1034836000341	ATP binding site [chemical binding]; other site
1034836000342	Walker B motif; other site
1034836000343	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
1034836000344	DNA repair protein RadA; Provisional; Region: PRK11823
1034836000345	Sms (bacterial radA) DNA repair protein. This protein is not related to archael radA any more than is to other RecA-like NTPases. Sms has a role in recombination and recombinational repair and is responsible for the stabilization or processing of...; Region: Sms; cd01121
1034836000346	Walker A motif/ATP binding site; other site
1034836000347	ATP binding site [chemical binding]; other site
1034836000348	Walker B motif; other site
1034836000349	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
1034836000350	DNA integrity scanning protein DisA; Provisional; Region: PRK13482
1034836000351	DisA bacterial checkpoint controller nucleotide-binding; Region: DisA_N; pfam02457
1034836000352	DisA bacterial checkpoint controller linker region; Region: DisA-linker; pfam10635
1034836000353	Integral membrane protein (PIN domain superfamily) [General function prediction only]; Region: COG4956
1034836000354	PIN domain of Thermus Thermophilus Hb8, uncharacterized Bacillus subtilis YacL, and other bacterial homologs; Region: PIN_YacL; cd09877
1034836000355	putative active site [active]
1034836000356	CDP-ME synthetase is involved in mevalonate-independent isoprenoid production; Region: CDP-ME_synthetase; cd02516
1034836000357	substrate binding site; other site
1034836000358	dimer interface; other site
1034836000359	MECDP_synthase (2-C-methyl-D-erythritol-2,4-cyclodiphosphate synthase), encoded by the ispF gene, catalyzes the formation of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (MEC) in the non-mevalonate deoxyxylulose (DOXP) pathway for isoprenoid biosynthesis; Region: MECDP_synthase; cd00554
1034836000360	homotrimer interaction site [polypeptide binding]; other site
1034836000361	zinc binding site [ion binding]; other site
1034836000362	CDP-binding sites; other site
1034836000363	glutamyl-tRNA synthetase; Reviewed; Region: gltX; PRK01406
1034836000364	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
1034836000365	HIGH motif; other site
1034836000366	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
1034836000367	active site
1034836000368	KMSKS motif; other site
1034836000369	serine O-acetyltransferase; Region: cysE; TIGR01172
1034836000370	Serine acetyltransferase, N-terminal; Region: SATase_N; cl05762
1034836000371	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
1034836000372	trimer interface [polypeptide binding]; other site
1034836000373	active site
1034836000374	substrate binding site [chemical binding]; other site
1034836000375	CoA binding site [chemical binding]; other site
1034836000376	cysteinyl-tRNA synthetase; Validated; Region: cysS; PRK00260
1034836000377	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
1034836000378	active site
1034836000379	HIGH motif; other site
1034836000380	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
1034836000381	KMSKS motif; other site
1034836000382	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
1034836000383	tRNA binding surface [nucleotide binding]; other site
1034836000384	anticodon binding site; other site
1034836000385	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
1034836000386	active site
1034836000387	metal binding site [ion binding]; metal-binding site
1034836000388	dimerization interface [polypeptide binding]; other site
1034836000389	rRNA methylase, putative, group 3; Region: rRNA_methyl_3; TIGR00186
1034836000390	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; pfam08032
1034836000391	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
1034836000392	Predicted RNA-binding protein containing a PIN domain [General function prediction only]; Region: COG3688
1034836000393	RNA polymerase factor sigma-70; Validated; Region: PRK08295
1034836000394	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1034836000395	Sigma-70, region 4; Region: Sigma70_r4_2; pfam08281
1034836000396	50S ribosomal protein L33; Validated; Region: rpmG; PRK00504
1034836000397	preprotein translocase subunit SecE; Reviewed; Region: secE; PRK07597
1034836000398	transcription antitermination protein NusG; Validated; Region: nusG; PRK05609
1034836000399	Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1; cd09891
1034836000400	putative homodimer interface [polypeptide binding]; other site
1034836000401	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
1034836000402	heterodimer interface [polypeptide binding]; other site
1034836000403	homodimer interface [polypeptide binding]; other site
1034836000404	50S ribosomal protein L11; Validated; Region: rplK; PRK00140
1034836000405	Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349
1034836000406	L7/L12 interface [polypeptide binding]; other site
1034836000407	23S rRNA interface [nucleotide binding]; other site
1034836000408	L25 interface [polypeptide binding]; other site
1034836000409	Ribosomal protein L1.  The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA.  In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403
1034836000410	mRNA/rRNA interface [nucleotide binding]; other site
1034836000411	Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797
1034836000412	23S rRNA interface [nucleotide binding]; other site
1034836000413	Interface with L7/L12 ribosomal proteins [polypeptide binding]; other site
1034836000414	Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cd00387
1034836000415	core dimer interface [polypeptide binding]; other site
1034836000416	peripheral dimer interface [polypeptide binding]; other site
1034836000417	L10 interface [polypeptide binding]; other site
1034836000418	L11 interface [polypeptide binding]; other site
1034836000419	putative EF-Tu interaction site [polypeptide binding]; other site
1034836000420	putative EF-G interaction site [polypeptide binding]; other site
1034836000421	16S RNA G1207 methylase RsmC [Translation, ribosomal structure and biogenesis]; Region: RsmC; COG2813
1034836000422	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1034836000423	S-adenosylmethionine binding site [chemical binding]; other site
1034836000424	DNA-directed RNA polymerase subunit beta; Reviewed; Region: rpoB; PRK00405
1034836000425	RNA polymerase Rpb2, domain 2; Region: RNA_pol_Rpb2_2; pfam04561
1034836000426	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585
1034836000427	RNA polymerase beta subunit external 1 domain; Region: RNA_pol_Rpb2_45; pfam10385
1034836000428	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
1034836000429	RPB1 interaction site [polypeptide binding]; other site
1034836000430	RPB10 interaction site [polypeptide binding]; other site
1034836000431	RPB11 interaction site [polypeptide binding]; other site
1034836000432	RPB3 interaction site [polypeptide binding]; other site
1034836000433	RPB12 interaction site [polypeptide binding]; other site
1034836000434	DNA-directed RNA polymerase subunit beta'; Provisional; Region: PRK00566
1034836000435	RNA polymerase Rpb1, domain 1; Region: RNA_pol_Rpb1_1; pfam04997
1034836000436	RNA polymerase I subunit A N-terminus; Region: RPOLA_N; smart00663
1034836000437	RNA polymerase Rpb1, domain 3; Region: RNA_pol_Rpb1_3; pfam04983
1034836000438	RNA polymerase Rpb1, domain 4; Region: RNA_pol_Rpb1_4; pfam05000
1034836000439	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
1034836000440	Rpb1 (beta') - Rpb6 (omega) interaction site [polypeptide binding]; other site
1034836000441	Rpb1 (beta') - Rpb2 (beta) interaction site [polypeptide binding]; other site
1034836000442	G-loop; other site
1034836000443	DNA binding site [nucleotide binding]
1034836000444	putative ribosomal protein L7Ae-like; Provisional; Region: PRK13602
1034836000445	30S ribosomal protein S7; Validated; Region: PRK05302
1034836000446	elongation factor G; Reviewed; Region: PRK00007
1034836000447	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
1034836000448	G1 box; other site
1034836000449	putative GEF interaction site [polypeptide binding]; other site
1034836000450	GTP/Mg2+ binding site [chemical binding]; other site
1034836000451	Switch I region; other site
1034836000452	G2 box; other site
1034836000453	G3 box; other site
1034836000454	Switch II region; other site
1034836000455	G4 box; other site
1034836000456	G5 box; other site
1034836000457	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
1034836000458	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
1034836000459	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
1034836000460	elongation factor Tu; Reviewed; Region: PRK00049
1034836000461	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
1034836000462	G1 box; other site
1034836000463	GEF interaction site [polypeptide binding]; other site
1034836000464	GTP/Mg2+ binding site [chemical binding]; other site
1034836000465	Switch I region; other site
1034836000466	G2 box; other site
1034836000467	G3 box; other site
1034836000468	Switch II region; other site
1034836000469	G4 box; other site
1034836000470	G5 box; other site
1034836000471	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
1034836000472	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
1034836000473	Antibiotic Binding Site [chemical binding]; other site
1034836000474	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
1034836000475	50S ribosomal protein L3; Validated; Region: rplC; PRK00001
1034836000476	Ribosomal protein L4/L1 family; Region: Ribosomal_L4; cl00325
1034836000477	50S ribosomal protein L23; Reviewed; Region: rplW; PRK05738
1034836000478	50S ribosomal protein L2; Validated; Region: rplB; PRK09374
1034836000479	Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181
1034836000480	Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947
1034836000481	30S ribosomal protein S19; Reviewed; Region: rpsS; PRK00357
1034836000482	30S ribosomal protein S3; Reviewed; Region: rpsC; PRK00310
1034836000483	K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3  is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel.  The KH...; Region: 30S_S3_KH; cd02412
1034836000484	G-X-X-G motif; other site
1034836000485	Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189
1034836000486	Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433
1034836000487	L27 interface [polypeptide binding]; other site
1034836000488	Ribosomal L29 protein/HIP.  L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals.  L29 is located on the surface of the large ribosomal subunit, where it...; Region: Ribosomal_L29_HIP; cd00427
1034836000489	23S rRNA interface [nucleotide binding]; other site
1034836000490	putative translocon interaction site; other site
1034836000491	signal recognition particle (SRP54) interaction site; other site
1034836000492	L23 interface [polypeptide binding]; other site
1034836000493	trigger factor interaction site; other site
1034836000494	30S ribosomal protein S17; Reviewed; Region: rpsQ; PRK05610
1034836000495	50S ribosomal protein L24; Reviewed; Region: rplX; PRK00004
1034836000496	KOW motif of Ribosomal Protein L26; Region: KOW_RPL26; cd06089
1034836000497	RNA binding site [nucleotide binding]; other site
1034836000498	50S ribosomal protein L5; Validated; Region: rplE; PRK00010
1034836000499	Ribosomal protein L5; Region: Ribosomal_L5; pfam00281
1034836000500	ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673
1034836000501	30S ribosomal protein S8; Validated; Region: rpsH; PRK00136
1034836000502	50S ribosomal protein L6; Validated; Region: rplF; PRK05498
1034836000503	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
1034836000504	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
1034836000505	Ribosomal L18/L5e:  L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432
1034836000506	23S rRNA interface [nucleotide binding]; other site
1034836000507	L5 interface [polypeptide binding]; other site
1034836000508	30S ribosomal protein S5; Validated; Region: rpsE; PRK00550
1034836000509	Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333
1034836000510	Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719
1034836000511	Ribosomal protein L30, which is found in eukaryotes and prokaryotes but not in archaea, is one of the smallest ribosomal proteins with a molecular mass of about 7kDa. L30 binds the 23SrRNA as well as the 5S rRNA and is one of five ribosomal proteins that...; Region: Ribosomal_L30; cd01658
1034836000512	23S rRNA binding site [nucleotide binding]; other site
1034836000513	50S ribosomal protein L15; Reviewed; Region: rplO; PRK05592
1034836000514	preprotein translocase, SecY subunit; Region: 3a0501s007; TIGR00967
1034836000515	SecY translocase; Region: SecY; pfam00344
1034836000516	adenylate kinase; Reviewed; Region: adk; PRK00279
1034836000517	Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428
1034836000518	AMP-binding site [chemical binding]; other site
1034836000519	ATP-AMP (Ap5A)-binding site [chemical binding]; other site
1034836000520	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
1034836000521	active site
1034836000522	50S ribosomal protein L36; Reviewed; Region: rpmJ; PRK00465
1034836000523	30S ribosomal protein S13; Validated; Region: rpsM; PRK05179
1034836000524	30S ribosomal protein S13; Region: bact_S13; TIGR03631
1034836000525	DNA-directed RNA polymerase subunit alpha; Provisional; Region: PRK05182
1034836000526	N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928
1034836000527	alphaNTD homodimer interface [polypeptide binding]; other site
1034836000528	alphaNTD - beta interaction site [polypeptide binding]; other site
1034836000529	alphaNTD - beta' interaction site [polypeptide binding]; other site
1034836000530	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118
1034836000531	cobalt transporter ATP-binding subunit; Provisional; Region: cbiO; PRK13635
1034836000532	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
1034836000533	Walker A/P-loop; other site
1034836000534	ATP binding site [chemical binding]; other site
1034836000535	Q-loop/lid; other site
1034836000536	ABC transporter signature motif; other site
1034836000537	Walker B; other site
1034836000538	D-loop; other site
1034836000539	H-loop/switch region; other site
1034836000540	cobalt transporter ATP-binding subunit; Provisional; Region: cbiO; PRK13634
1034836000541	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
1034836000542	Walker A/P-loop; other site
1034836000543	ATP binding site [chemical binding]; other site
1034836000544	Q-loop/lid; other site
1034836000545	ABC transporter signature motif; other site
1034836000546	Walker B; other site
1034836000547	D-loop; other site
1034836000548	H-loop/switch region; other site
1034836000549	ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism]; Region: CbiQ; COG0619
1034836000550	tRNA pseudouridine synthase A; Validated; Region: truA; PRK00021
1034836000551	Eukaryotic and bacterial pseudouridine synthases similar to E.  coli TruA; Region: PseudoU_synth_EcTruA; cd02570
1034836000552	dimerization interface 3.5A [polypeptide binding]; other site
1034836000553	active site
1034836000554	Ribosomal protein L13.  Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392
1034836000555	23S rRNA interface [nucleotide binding]; other site
1034836000556	L3 interface [polypeptide binding]; other site
1034836000557	Methyltransferase domain; Region: Methyltransf_31; pfam13847
1034836000558	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1034836000559	S-adenosylmethionine binding site [chemical binding]; other site
1034836000560	Protein of unknown function (DUF2521); Region: DUF2521; pfam10730
1034836000561	N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: AmiC; COG0860
1034836000562	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
1034836000563	active site
1034836000564	metal binding site [ion binding]; metal-binding site
1034836000565	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Mrp; COG0489
1034836000566	MRP (Multiple Resistance and pH adaptation) is a homologue of the Fer4_NifH superfamily. Like the other members of the superfamily, MRP contains a ATP-binding domain at the N-termini. It is found in bacteria as a membrane-spanning protein and functions...; Region: MRP-like; cd02037
1034836000567	KinB-signalling pathway activation in sporulation; Region: KbaA; pfam14089
1034836000568	Predicted xylanase/chitin deacetylase [Carbohydrate transport and metabolism]; Region: CDA1; COG0726
1034836000569	Catalytic NodB homology domain of the carbohydrate esterase 4 superfamily; Region: CE4_SF; cl15692
1034836000570	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1034836000571	4-aminobutyrate aminotransferase and related aminotransferases [Amino acid transport and metabolism]; Region: GabT; COG0160
1034836000572	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1034836000573	inhibitor-cofactor binding pocket; inhibition site
1034836000574	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1034836000575	catalytic residue [active]
1034836000576	FIG, FBPase/IMPase/glpX-like domain. A superfamily of metal-dependent phosphatases with various substrates. Fructose-1,6-bisphospatase (both the major and the glpX-encoded variant) hydrolyze fructose-1,6,-bisphosphate to fructose-6-phosphate in...; Region: FIG; cl00289
1034836000577	active site
1034836000578	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
1034836000579	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
1034836000580	NAD(P) binding site [chemical binding]; other site
1034836000581	Carbamoyltransferase; Region: CmcH_NodU; pfam02543
1034836000582	Sulfate transporter N-terminal domain with GLY motif; Region: Sulfate_tra_GLY; pfam13792
1034836000583	Sulfate permease and related transporters (MFS superfamily) [Inorganic ion transport and metabolism]; Region: SUL1; COG0659
1034836000584	Sulfate transporter family; Region: Sulfate_transp; pfam00916
1034836000585	Sulphate Transporter and Anti-Sigma factor antagonist domain of SulP-like sulfate transporters, plays a role in the function and regulation of the transport activity, proposed general NTP binding function; Region: STAS_SulP_like_sulfate_transporter; cd07042
1034836000586	Predicted Na+-dependent transporter [General function prediction only]; Region: COG0385
1034836000587	Sodium Bile acid symporter family; Region: SBF; cl17470
1034836000588	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
1034836000589	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
1034836000590	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1034836000591	ABC-ATPase subunit  interface; other site
1034836000592	dimer interface [polypeptide binding]; other site
1034836000593	putative PBP binding regions; other site
1034836000594	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
1034836000595	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1034836000596	ABC-ATPase subunit  interface; other site
1034836000597	dimer interface [polypeptide binding]; other site
1034836000598	putative PBP binding regions; other site
1034836000599	ABC-type Fe3+-hydroxamate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: FepB; COG0614
1034836000600	Periplasmic binding protein FeuA.  These proteins have predicted to function as initial receptors in ABC transport of metal ions in some eubacterial species.  They belong to the TroA superfamily of periplasmic metal binding proteins that share a distinct...; Region: FeuA; cd01138
1034836000601	putative ligand binding residues [chemical binding]; other site
1034836000602	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1034836000603	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1034836000604	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1034836000605	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
1034836000606	ABC-type Fe3+-hydroxamate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: FepB; COG0614
1034836000607	intersubunit interface [polypeptide binding]; other site
1034836000608	Protein of unknown function (DUF1343); Region: DUF1343; pfam07075
1034836000609	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
1034836000610	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
1034836000611	Glycosyl hydrolase family 3 C-terminal domain; Region: Glyco_hydro_3_C; pfam01915
1034836000612	putative periplasmic esterase; Provisional; Region: PRK03642
1034836000613	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
1034836000614	PTS system, sucrose-specific IIBC component; Region: PTS-II-BC-sucr; TIGR01996
1034836000615	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1034836000616	active site turn [active]
1034836000617	phosphorylation site [posttranslational modification]
1034836000618	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1034836000619	N-acetylmuramic acid-6-phosphate etherase; Reviewed; Region: murQ; PRK05441
1034836000620	N-acetylmuramic acid 6-phosphate etherase. Members of this family contain the SIS (Sugar ISomerase) domain. The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. The bacterial cell wall sugar N-acetylmuramic acid...; Region: SIS_Etherase; cd05007
1034836000621	putative active site [active]
1034836000622	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
1034836000623	Uncharacterized conserved protein [Function unknown]; Region: COG1683
1034836000624	RNA polymerase sigma factor SigW; Provisional; Region: PRK09641
1034836000625	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1034836000626	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1034836000627	DNA binding residues [nucleotide binding]
1034836000628	Predicted transmembrane transcriptional regulator (anti-sigma factor) [Transcription]; Region: COG5662
1034836000629	mycothiol system anti-sigma-R factor; Region: antisig_RsrA; cl15806
1034836000630	Polymer-forming cytoskeletal; Region: Bactofilin; pfam04519
1034836000631	Uncharacterized conserved protein [Function unknown]; Region: COG1624
1034836000632	DisA bacterial checkpoint controller nucleotide-binding; Region: DisA_N; pfam02457
1034836000633	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4856
1034836000634	YbbR-like protein; Region: YbbR; pfam07949
1034836000635	YbbR-like protein; Region: YbbR; pfam07949
1034836000636	YbbR-like protein; Region: YbbR; pfam07949
1034836000637	phosphoglucosamine mutase; Provisional; Region: glmM; PRK14316
1034836000638	GlmM is a bacterial phosphoglucosamine mutase (PNGM) that belongs to the alpha-D-phosphohexomutase superfamily. It is required for the interconversion of glucosamine-6-phosphate and glucosamine-1-phosphate in the biosynthetic pathway of...; Region: GlmM; cd05802
1034836000639	active site
1034836000640	substrate binding site [chemical binding]; other site
1034836000641	metal binding site [ion binding]; metal-binding site
1034836000642	glucosamine--fructose-6-phosphate aminotransferase; Reviewed; Region: PRK00331
1034836000643	Glutamine amidotransferases class-II (Gn-AT)_GFAT-type. This domain is found at the N-terminus of glucosamine-6P synthase (GlmS, or GFAT in humans).  The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the appropriate substrate. In...; Region: GFAT; cd00714
1034836000644	glutaminase active site [active]
1034836000645	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
1034836000646	dimer interface [polypeptide binding]; other site
1034836000647	active site
1034836000648	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
1034836000649	dimer interface [polypeptide binding]; other site
1034836000650	active site
1034836000651	Myosin and Kinesin motor domain. These ATPases belong to the P-loop NTPase family and provide the driving force in myosin and kinesin mediated processes; Region: Motor_domain; cl00286
1034836000652	ABC-2 family transporter protein; Region: ABC2_membrane_5; pfam13346
1034836000653	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1034836000654	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1034836000655	active site
1034836000656	catalytic tetrad [active]
1034836000657	Putative effector of murein hydrolase [Cell envelope biogenesis, outer membrane]; Region: LrgB; COG1346
1034836000658	LrgA family; Region: LrgA; cl00608
1034836000659	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1034836000660	MarR family; Region: MarR; pfam01047
1034836000661	putative transport protein YifK; Provisional; Region: PRK10746
1034836000662	HAD superfamily (subfamily IA) hydrolase, TIGR02254; Region: YjjG/YfnB
1034836000663	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1034836000664	active site
1034836000665	motif I; other site
1034836000666	motif II; other site
1034836000667	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG4585
1034836000668	Histidine kinase; Region: HisKA_3; pfam07730
1034836000669	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Region: HATPase_c; pfam02518
1034836000670	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1034836000671	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1034836000672	active site
1034836000673	phosphorylation site [posttranslational modification]
1034836000674	intermolecular recognition site; other site
1034836000675	dimerization interface [polypeptide binding]; other site
1034836000676	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1034836000677	DNA binding residues [nucleotide binding]
1034836000678	dimerization interface [polypeptide binding]; other site
1034836000679	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
1034836000680	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1034836000681	Walker A/P-loop; other site
1034836000682	ATP binding site [chemical binding]; other site
1034836000683	Q-loop/lid; other site
1034836000684	ABC transporter signature motif; other site
1034836000685	Walker B; other site
1034836000686	D-loop; other site
1034836000687	H-loop/switch region; other site
1034836000688	ABC-2 family transporter protein; Region: ABC2_membrane_3; pfam12698
1034836000689	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
1034836000690	ABC-type Na+ efflux pump, permease component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatB; COG1668
1034836000691	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
1034836000692	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
1034836000693	potential frameshift: common BLAST hit: gi|154684725|ref|YP_001419886.1| YqeB
1034836000694	Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531
1034836000695	Glycerophosphoryl diester phosphodiesterase [Energy production and conversion]; Region: UgpQ; COG0584
1034836000696	Glycerophosphodiester phosphodiesterase domain of Staphylococcus aureus and similar proteins; Region: GDPD_SaGlpQ_like; cd08601
1034836000697	active site
1034836000698	catalytic site [active]
1034836000699	metal binding site [ion binding]; metal-binding site
1034836000700	glycerol-3-phosphate transporter; Region: glpT; TIGR00712
1034836000701	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1034836000702	putative substrate translocation pore; other site
1034836000703	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1034836000704	Protein of unknown function (DUF2651); Region: DUF2651; pfam10852
1034836000705	Aromatic ring hydroxylase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG2368
1034836000706	4-hydroxyphenylacetate 3-hydroxylase C terminal; Region: HpaB; pfam03241
1034836000707	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1034836000708	non-specific DNA binding site [nucleotide binding]; other site
1034836000709	salt bridge; other site
1034836000710	sequence-specific DNA binding site [nucleotide binding]; other site
1034836000711	Glycerol dehydrogenase and related enzymes [Energy production and conversion]; Region: GldA; COG0371
1034836000712	Glycerol_dehydrogenase-like; Region: GlyDH-like; cd08550
1034836000713	active site
1034836000714	NAD binding site [chemical binding]; other site
1034836000715	metal binding site [ion binding]; metal-binding site
1034836000716	phosphoribosylglycinamide formyltransferase 2; Validated; Region: purT; PRK09288
1034836000717	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1034836000718	ATP-grasp domain; Region: ATP-grasp; pfam02222
1034836000719	CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; pfam01066
1034836000720	CDP-diacylglycerol--serine O-phosphatidyltransferase; Region: pssA; TIGR00473
1034836000721	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1034836000722	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
1034836000723	phosphatidylserine decarboxylase; Provisional; Region: PRK03140
1034836000724	putative rhodanese-related sulfurtransferase; Provisional; Region: PRK00142
1034836000725	Member of the Rhodanese Homology Domain superfamily. This CD includes Escherichia coli YceA, Bacillus subtilis YbfQ, and similar uncharacterized proteins; Region: RHOD_YceA; cd01518
1034836000726	active site residue [active]
1034836000727	Protein of unknown function (DUF3650); Region: DUF3650; pfam12368
1034836000728	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
1034836000729	Sodium:dicarboxylate symporter family; Region: SDF; cl00573
1034836000730	branched-chain amino acid aminotransferase; Provisional; Region: PRK13357
1034836000731	BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids  leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and...; Region: BCAT_beta_family; cd01557
1034836000732	homodimer interface [polypeptide binding]; other site
1034836000733	substrate-cofactor binding pocket; other site
1034836000734	catalytic residue [active]
1034836000735	S-methylmethionine transporter; Provisional; Region: PRK11387
1034836000736	homocysteine methyltransferase; Provisional; Region: mmuM; PRK09485
1034836000737	Homocysteine S-methyltransferase; Region: S-methyl_trans; pfam02574
1034836000738	Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115
1034836000739	Sodium:alanine symporter family; Region: Na_Ala_symp; pfam01235
1034836000740	glutaminase; Reviewed; Region: PRK12357
1034836000741	Glutaminase [Amino acid transport and metabolism]; Region: GlsA; COG2066
1034836000742	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1034836000743	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1034836000744	ATP binding site [chemical binding]; other site
1034836000745	Mg2+ binding site [ion binding]; other site
1034836000746	G-X-G motif; other site
1034836000747	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1034836000748	Response regulator receiver domain; Region: Response_reg; pfam00072
1034836000749	active site
1034836000750	phosphorylation site [posttranslational modification]
1034836000751	intermolecular recognition site; other site
1034836000752	dimerization interface [polypeptide binding]; other site
1034836000753	YcbB domain; Region: YcbB; pfam08664
1034836000754	Macrolide 2'-Phosphotransferase (MPH2'). MPH2' is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs), RIO kinases, actin-fragmin kinase; Region: MPH2' cd05152
1034836000755	putative active site [active]
1034836000756	putative substrate binding site [chemical binding]; other site
1034836000757	Phosphotransferase enzyme family; Region: APH; pfam01636
1034836000758	ATP binding site [chemical binding]; other site
1034836000759	anti-TRAP (AT) protein specific to Bacilli; Region: anti-TRAP; cd10748
1034836000760	dodecamer interface 1 [polypeptide binding]; other site
1034836000761	dodecamer interface 2 [polypeptide binding]; other site
1034836000762	trimer interface [polypeptide binding]; other site
1034836000763	TRAP binding interface [polypeptide binding]; other site
1034836000764	Zn binding site [ion binding]; other site
1034836000765	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
1034836000766	cation diffusion facilitator family transporter; Region: CDF; TIGR01297
1034836000767	Nitroreductase-like family 1. A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and...; Region: Nitroreductase_1; cd02137
1034836000768	dimer interface [polypeptide binding]; other site
1034836000769	FMN binding site [chemical binding]; other site
1034836000770	N-terminal domain of Sphingobium chlorophenolicum 2,6-dichloro-p-hydroquinone 1,2-dioxygenase (PcpA), and similar proteins; Region: PcpA_N_like; cd08346
1034836000771	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1034836000772	Zn binding site [ion binding]; other site
1034836000773	C-terminal domain of Sphingobium chlorophenolicum 2,6-dichloro-p-hydroquinone 1,2-dioxygenase (PcpA), and similar proteins; Region: PcpA_C_like; cd08347
1034836000774	Zn binding site [ion binding]; other site
1034836000775	Predicted membrane protein [Function unknown]; Region: COG2259
1034836000776	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
1034836000777	catalytic residues [active]
1034836000778	Protein of unknown function (DUF2512); Region: DUF2512; pfam10710
1034836000779	Cell wall hydrolyses involved in spore germination [Cell envelope biogenesis, outer membrane]; Region: SleB; COG3773
1034836000780	Cell Wall Hydrolase; Region: Hydrolase_2; pfam07486
1034836000781	Phosphodiesterase/alkaline phosphatase D [Inorganic ion transport and metabolism]; Region: PhoD; COG3540
1034836000782	Bacillus subtilis PhoD and related proteins, metallophosphatase domain; Region: MPP_PhoD; cd07389
1034836000783	putative active site [active]
1034836000784	putative metal binding site [ion binding]; other site
1034836000785	twin arginine translocase protein A; Provisional; Region: tatA; PRK14861
1034836000786	Sec-independent protein secretion pathway component TatC [Intracellular trafficking and secretion]; Region: TatC; COG0805
1034836000787	Pyroglutamyl peptidase (PGP) type I, also known as pyrrolidone carboxyl peptidase (pcp) type I:  Enzymes responsible for cleaving pyroglutamate (pGlu) from the N-terminal end of specialized proteins. The N-terminal pGlu protects these proteins from...; Region: Peptidase_C15; cd00501
1034836000788	putative substrate binding pocket [chemical binding]; other site
1034836000789	AC domain interface; other site
1034836000790	catalytic triad [active]
1034836000791	AB domain interface; other site
1034836000792	interchain disulfide; other site
1034836000793	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
1034836000794	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
1034836000795	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1034836000796	catalytic residue [active]
1034836000797	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1034836000798	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1034836000799	putative substrate translocation pore; other site
1034836000800	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1034836000801	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1034836000802	Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold [General function prediction only]; Region: LipA; COG1075
1034836000803	Lipase (class 2); Region: Lipase_2; pfam01674
1034836000804	Predicted metal-binding protein related to the C-terminal domain of SecA [General function prediction only]; Region: COG3318
1034836000805	helix-turn-helix, Psq domain; Region: HTH_psq; pfam05225
1034836000806	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1034836000807	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1034836000808	active site
1034836000809	catalytic tetrad [active]
1034836000810	Domain of unknown function (DUF4352); Region: DUF4352; pfam11611
1034836000811	D-alanyl-D-alanine carboxypeptidase; Region: VanY; pfam02557
1034836000812	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1034836000813	binding surface
1034836000814	TPR motif; other site
1034836000815	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
1034836000816	Tetratricopeptide repeat; Region: TPR_12; pfam13424
1034836000817	TPR motif; other site
1034836000818	binding surface
1034836000819	glucose-1-dehydrogenase; Provisional; Region: PRK08936
1034836000820	glucose 1 dehydrogenase (GlcDH), classical (c) SDRs; Region: GlcDH_SDR_c; cd05358
1034836000821	NAD binding site [chemical binding]; other site
1034836000822	homodimer interface [polypeptide binding]; other site
1034836000823	active site
1034836000824	alpha,alpha-phosphotrehalase; Region: trehalose_treC; TIGR02403
1034836000825	Alpha amylase catalytic domain found in Sucrose isomerases, oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase), dextran glucosidase (also called glucan 1,6-alpha-glucosidase), and related proteins; Region: AmyAc_SI_OligoGlu_DGase; cd11333
1034836000826	Ca binding site [ion binding]; other site
1034836000827	active site
1034836000828	catalytic site [active]
1034836000829	Domain of unknown function (DUF4188); Region: DUF4188; pfam13826
1034836000830	Predicted transcriptional regulators [Transcription]; Region: COG1695
1034836000831	Transcriptional regulator PadR-like family; Region: PadR; cl17335
1034836000832	Virulence activator alpha C-term; Region: Vir_act_alpha_C; pfam10400
1034836000833	ABC-type metal ion transport system, periplasmic component/surface adhesin [Inorganic ion transport and metabolism]; Region: LraI; COG0803
1034836000834	Metal binding protein AcdA.  These proteins have been shown to function in the ABC uptake of Zn2+ and Mn2+ and in competence for genetic transformation and adhesion. The AcdA proteins belong to the TroA superfamily of helical backbone metal receptor...; Region: AdcA; cd01017
1034836000835	metal binding site [ion binding]; metal-binding site
1034836000836	ABC-type Mn/Zn transport systems, ATPase component [Inorganic ion transport and metabolism]; Region: ZnuC; COG1121
1034836000837	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
1034836000838	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
1034836000839	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1034836000840	ABC-ATPase subunit  interface; other site
1034836000841	dimer interface [polypeptide binding]; other site
1034836000842	putative PBP binding regions; other site
1034836000843	Flavin-utilizing monoxygenases; Region: Flavin_utilizing_monoxygenases; cd00347
1034836000844	luciferase family oxidoreductase, group 1; Region: oxido_grp_1; TIGR03558
1034836000845	Flavin-utilizing monoxygenases; Region: Flavin_utilizing_monoxygenases; cl07892
1034836000846	Flavin-utilizing monoxygenases; Region: Flavin_utilizing_monoxygenases; cd00347
1034836000847	Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1 [Signal transduction mechanisms]; Region: TerZ; COG2310
1034836000848	Uncharacterized proteins involved in stress response, similar to tellurium resistance terD; Region: TerD_like; cd06974
1034836000849	putative metal binding site [ion binding]; other site
1034836000850	Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1 [Signal transduction mechanisms]; Region: TerZ; COG2310
1034836000851	Uncharacterized proteins involved in stress response, similar to tellurium resistance terD; Region: TerD_like; cd06974
1034836000852	putative metal binding site [ion binding]; other site
1034836000853	Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1 [Signal transduction mechanisms]; Region: TerZ; COG2310
1034836000854	Uncharacterized proteins involved in stress response, similar to tellurium resistance terD; Region: TerD_like; cd06974
1034836000855	putative metal binding site [ion binding]; other site
1034836000856	integral membrane protein, YkoY family; Region: R_switched_YkoY; TIGR03716
1034836000857	Domain of unknown function (DUF4356); Region: DUF4356; pfam14266
1034836000858	Toxic anion resistance protein (TelA); Region: TelA; pfam05816
1034836000859	benzoate transport; Region: 2A0115; TIGR00895
1034836000860	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1034836000861	putative substrate translocation pore; other site
1034836000862	ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and metabolism]; Region: ProV; COG4175
1034836000863	ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; Region: ABC_Pro_Gly_Betaine; cd03294
1034836000864	Walker A/P-loop; other site
1034836000865	ATP binding site [chemical binding]; other site
1034836000866	Q-loop/lid; other site
1034836000867	ABC transporter signature motif; other site
1034836000868	Walker B; other site
1034836000869	D-loop; other site
1034836000870	H-loop/switch region; other site
1034836000871	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cl15354
1034836000872	glycine betaine transporter membrane protein; Provisional; Region: PRK10952
1034836000873	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1034836000874	dimer interface [polypeptide binding]; other site
1034836000875	conserved gate region; other site
1034836000876	putative PBP binding loops; other site
1034836000877	ABC-ATPase subunit interface; other site
1034836000878	ABC-type proline/glycine betaine transport systems, periplasmic components [Amino acid transport and metabolism]; Region: ProX; cl17891
1034836000879	Substrate binding domain of ABC-type glycine betaine transport system; Region: OpuAC; pfam04069
1034836000880	Substrate binding domain of ABC-type glycine betaine transport system; Region: OpuAC; pfam04069
1034836000881	M20 Peptidase Aminoacylase 1 amhX_like subfamily; Region: M20_Acy1_amhX_like; cd08018
1034836000882	amidohydrolase; Region: amidohydrolases; TIGR01891
1034836000883	metal binding site [ion binding]; metal-binding site
1034836000884	putative dimer interface [polypeptide binding]; other site
1034836000885	Predicted membrane protein [Function unknown]; Region: COG1288
1034836000886	C4-dicarboxylate anaerobic carrier; Region: DcuC; pfam03606
1034836000887	RDD family; Region: RDD; pfam06271
1034836000888	RDD family; Region: RDD; pfam06271
1034836000889	L-lactate dehydrogenase; Reviewed; Region: ldh; PRK00066
1034836000890	L-2-hydroxyisocapronate dehydrogenases and some bacterial L-lactate dehydrogenases; Region: HicDH_like; cd05291
1034836000891	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1034836000892	NAD binding site [chemical binding]; other site
1034836000893	dimer interface [polypeptide binding]; other site
1034836000894	substrate binding site [chemical binding]; other site
1034836000895	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1034836000896	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1034836000897	putative substrate translocation pore; other site
1034836000898	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1034836000899	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1034836000900	MarR family; Region: MarR; pfam01047
1034836000901	LysE type translocator; Region: LysE; pfam01810
1034836000902	Uncharacterized conserved protein [Function unknown]; Region: COG3403
1034836000903	Gamma-aminobutyrate permease and related permeases [Amino acid transport and metabolism]; Region: AnsP; COG1113
1034836000904	Spore germination protein; Region: Spore_permease; cl17796
1034836000905	Domain of unknown function (DUF1989); Region: DUF1989; cl01474
1034836000906	urea carboxylase-associated protein 1; Region: urea_degr_1; TIGR03424
1034836000907	NAD synthase [Coenzyme metabolism]; Region: NadE; COG0171
1034836000908	NAD+ synthase is a homodimer, which catalyzes the final step in de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis, an amide transfer from either ammonia or glutamine to nicotinic acid adenine dinucleotide (NaAD). The conversion of NaAD to NAD...; Region: NAD_synthase; cd00553
1034836000909	homodimer interface [polypeptide binding]; other site
1034836000910	NAD binding pocket [chemical binding]; other site
1034836000911	ATP binding pocket [chemical binding]; other site
1034836000912	Mg binding site [ion binding]; other site
1034836000913	active-site loop [active]
1034836000914	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
1034836000915	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
1034836000916	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1034836000917	D-galactonate transporter; Region: 2A0114; TIGR00893
1034836000918	putative substrate translocation pore; other site
1034836000919	shikimate kinase; Reviewed; Region: aroK; PRK00131
1034836000920	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
1034836000921	ADP binding site [chemical binding]; other site
1034836000922	magnesium binding site [ion binding]; other site
1034836000923	putative shikimate binding site; other site
1034836000924	Acetyl xylan esterase (AXE1); Region: AXE1; pfam05448
1034836000925	Predicted nucleotidyltransferase; Region: Nuc-transf; pfam10127
1034836000926	Proline dehydrogenase; Region: Pro_dh; pfam01619
1034836000927	1-pyrroline-5-carboxylate dehydrogenase; Provisional; Region: PRK03137
1034836000928	Delta(1)-pyrroline-5-carboxylate dehydrogenase, RocA; Region: ALDH_PutA-P5CDH-RocA; cd07124
1034836000929	Glutamate binding site [chemical binding]; other site
1034836000930	homodimer interface [polypeptide binding]; other site
1034836000931	NAD binding site [chemical binding]; other site
1034836000932	catalytic residues [active]
1034836000933	Na(+)/proline cotransporter PutP and related proteins; solute binding domain; Region: SLC5sbd_PutP; cd11475
1034836000934	Na binding site [ion binding]; other site
1034836000935	Regulator of polyketide synthase expression [Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG2508
1034836000936	PucR C-terminal helix-turn-helix domain; Region: HTH_30; pfam13556
1034836000937	Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones]; Region: TrxB; COG0492
1034836000938	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1034836000939	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1034836000940	Uroporphyrin-III C-methyltransferase (S-Adenosyl-L-methionine:uroporphyrinogen III methyltransferase, SUMT); Region: SUMT; cd11642
1034836000941	active site
1034836000942	SAM binding site [chemical binding]; other site
1034836000943	homodimer interface [polypeptide binding]; other site
1034836000944	Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in...; Region: HemD; cd06578
1034836000945	Small subunit of nitrite reductase (NirD) family, Rieske domain; composed of proteins similar to the Bacillus subtilis small subunit of assimilatory nitrite reductase containing a Rieske domain. The Rieske domain is a [2Fe-2S] cluster binding domain...; Region: Rieske_NirD_small_Bacillus; cd03530
1034836000946	[2Fe-2S] cluster binding site [ion binding]; other site
1034836000947	nitrite reductase [NAD(P)H], large subunit; Region: nitri_red_nirB; TIGR02374
1034836000948	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1034836000949	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
1034836000950	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
1034836000951	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
1034836000952	Nitrate/nitrite transporter [Inorganic ion transport and metabolism]; Region: NarK; COG2223
1034836000953	Putative GTPases (G3E family) [General function prediction only]; Region: COG0523
1034836000954	CobW/HypB/UreG, nucleotide-binding domain; Region: cobW; pfam02492
1034836000955	Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; smart00833
1034836000956	Glutathione-dependent formaldehyde dehydrogenase related proteins, child 1; Region: FDH_like_1; cd08283
1034836000957	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
1034836000958	NAD binding site [chemical binding]; other site
1034836000959	catalytic Zn binding site [ion binding]; other site
1034836000960	structural Zn binding site [ion binding]; other site
1034836000961	RDD family; Region: RDD; pfam06271
1034836000962	Protein of unknown function (DUF2680); Region: DUF2680; pfam10925
1034836000963	Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase [Carbohydrate transport and metabolism]; Region: BglB; COG2723
1034836000964	beta-galactosidase; Region: BGL; TIGR03356
1034836000965	Competence protein J (ComJ); Region: ComJ; pfam11033
1034836000966	Deoxyribonuclease NucA/NucB; Region: DNase_NucA_NucB; pfam14040
1034836000967	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
1034836000968	Hexulose-6-phosphate isomerase (PHI). PHI is a member of the SIS (Sugar ISomerase domain) superfamily. In the ribulose monophosphate pathway of formaldehyde fixation, hexulose-6-phosphate synthase catalyzes the condensation of ribulose-5-phosphate with...; Region: SIS_PHI; cd05005
1034836000969	tetramer interface [polypeptide binding]; other site
1034836000970	active site
1034836000971	3-Keto-L-gulonate 6-phosphate decarboxylase (KGPDC) and D-arabino-3-hexulose-6-phosphate synthase (HPS). KGPDC catalyzes the formation of L-xylulose 5-phosphate and carbon dioxide from 3-keto-L-gulonate 6-phosphate as part of the anaerobic pathway for...; Region: KGPDC_HPS; cd04726
1034836000972	active site
1034836000973	dimer interface [polypeptide binding]; other site
1034836000974	magnesium binding site [ion binding]; other site
1034836000975	Predicted transcriptional regulators [Transcription]; Region: COG1733
1034836000976	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
1034836000977	Condensation domain; Region: Condensation; pfam00668
1034836000978	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
1034836000979	HxxPF-repeated domain; Region: HxxPF_rpt; pfam13745
1034836000980	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
1034836000981	acyl-activating enzyme (AAE) consensus motif; other site
1034836000982	AMP binding site [chemical binding]; other site
1034836000983	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
1034836000984	Condensation domain; Region: Condensation; pfam00668
1034836000985	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
1034836000986	HxxPF-repeated domain; Region: HxxPF_rpt; pfam13745
1034836000987	The adenylation domain of nonribosomal peptide synthetases (NRPS), including Bacillus subtilis termination module Surfactin (SrfA-C); Region: A_NRPS_Srf_like; cd12117
1034836000988	acyl-activating enzyme (AAE) consensus motif; other site
1034836000989	AMP binding site [chemical binding]; other site
1034836000990	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
1034836000991	Condensation domain; Region: Condensation; pfam00668
1034836000992	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
1034836000993	HxxPF-repeated domain; Region: HxxPF_rpt; pfam13745
1034836000994	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
1034836000995	acyl-activating enzyme (AAE) consensus motif; other site
1034836000996	AMP binding site [chemical binding]; other site
1034836000997	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
1034836000998	Condensation domain; Region: Condensation; pfam00668
1034836000999	non-ribosomal peptide synthase domain TIGR01720; Region: NRPS-para261
1034836001000	Condensation domain; Region: Condensation; pfam00668
1034836001001	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
1034836001002	The adenylation domain of nonribosomal peptide synthetases (NRPS), including Bacillus subtilis termination module Surfactin (SrfA-C); Region: A_NRPS_Srf_like; cd12117
1034836001003	acyl-activating enzyme (AAE) consensus motif; other site
1034836001004	AMP binding site [chemical binding]; other site
1034836001005	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
1034836001006	Condensation domain; Region: Condensation; pfam00668
1034836001007	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
1034836001008	HxxPF-repeated domain; Region: HxxPF_rpt; pfam13745
1034836001009	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
1034836001010	acyl-activating enzyme (AAE) consensus motif; other site
1034836001011	AMP binding site [chemical binding]; other site
1034836001012	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
1034836001013	Condensation domain; Region: Condensation; pfam00668
1034836001014	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
1034836001015	HxxPF-repeated domain; Region: HxxPF_rpt; pfam13745
1034836001016	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
1034836001017	acyl-activating enzyme (AAE) consensus motif; other site
1034836001018	AMP binding site [chemical binding]; other site
1034836001019	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
1034836001020	Condensation domain; Region: Condensation; pfam00668
1034836001021	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
1034836001022	non-ribosomal peptide synthase domain TIGR01720; Region: NRPS-para261
1034836001023	Condensation domain; Region: Condensation; pfam00668
1034836001024	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
1034836001025	The adenylation domain of nonribosomal peptide synthetases (NRPS), including Bacillus subtilis termination module Surfactin (SrfA-C); Region: A_NRPS_Srf_like; cd12117
1034836001026	acyl-activating enzyme (AAE) consensus motif; other site
1034836001027	AMP binding site [chemical binding]; other site
1034836001028	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
1034836001029	Thioesterase domains of type I polyketide synthases or non-ribosomal peptide synthetases [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3319
1034836001030	Predicted thioesterase involved in non-ribosomal peptide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]; Region: GrsT; COG3208
1034836001031	Protein of unknown function (DUF3089); Region: DUF3089; pfam11288
1034836001032	Aspartate/tyrosine/aromatic aminotransferase [Amino acid transport and metabolism]; Region: COG0436
1034836001033	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1034836001034	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1034836001035	homodimer interface [polypeptide binding]; other site
1034836001036	catalytic residue [active]
1034836001037	Phosphopantetheinyl transferase [Coenzyme metabolism]; Region: Sfp; COG2091
1034836001038	phosphopantetheine--protein transferase domain; Region: pantethn_trn; TIGR00556
1034836001039	Predicted membrane protein [Function unknown]; Region: COG2364
1034836001040	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
1034836001041	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
1034836001042	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
1034836001043	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1034836001044	Walker A/P-loop; other site
1034836001045	ATP binding site [chemical binding]; other site
1034836001046	Q-loop/lid; other site
1034836001047	ABC transporter signature motif; other site
1034836001048	Walker B; other site
1034836001049	D-loop; other site
1034836001050	H-loop/switch region; other site
1034836001051	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1034836001052	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1034836001053	dimer interface [polypeptide binding]; other site
1034836001054	conserved gate region; other site
1034836001055	putative PBP binding loops; other site
1034836001056	ABC-ATPase subunit interface; other site
1034836001057	Bacterial periplasmic substrate-binding proteins; Region: PBPb; smart00062
1034836001058	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1034836001059	substrate binding pocket [chemical binding]; other site
1034836001060	membrane-bound complex binding site; other site
1034836001061	hinge residues; other site
1034836001062	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1034836001063	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1034836001064	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1034836001065	dimerization interface [polypeptide binding]; other site
1034836001066	3-polyprenyl-4-hydroxybenzoate decarboxylase [Coenzyme metabolism]; Region: UbiX; COG0163
1034836001067	Flavoprotein; Region: Flavoprotein; pfam02441
1034836001068	UbiD family decarboxylase; Region: TIGR00148
1034836001069	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
1034836001070	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1034836001071	Pectate lyase superfamily protein; Region: Pectate_lyase_3; pfam12708
1034836001072	Right handed beta helix region; Region: Beta_helix; pfam13229
1034836001073	Right handed beta helix region; Region: Beta_helix; pfam13229
1034836001074	Bacillus/Clostridium GerA spore germination protein; Region: GerA; pfam03323
1034836001075	germination protein, Ger(x)C family; Region: spore_ger_x_C; TIGR02887
1034836001076	Spore germination B3/ GerAC like, C-terminal; Region: Spore_GerAC; pfam05504
1034836001077	Spore germination protein; Region: Spore_permease; pfam03845
1034836001078	nitrilotriacetate monoxygenase oxidizes nitrilotriacetate utilizing reduced flavin mononucleotide (FMNH2) and oxygen. The FMNH2 is provided by an NADH:flavin mononucleotide (FMN) oxidorductase that uses NADH to reduce FMN to FMNH2; Region: Nitrilotriacetate_monoxgenase; cd01095
1034836001079	FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family; Region: FMN_nitrolo; TIGR03860
1034836001080	active site
1034836001081	non-prolyl cis peptide bond; other site
1034836001082	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1034836001083	Coenzyme A binding pocket [chemical binding]; other site
1034836001084	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
1034836001085	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1034836001086	substrate binding pocket [chemical binding]; other site
1034836001087	membrane-bound complex binding site; other site
1034836001088	hinge residues; other site
1034836001089	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1034836001090	dimer interface [polypeptide binding]; other site
1034836001091	conserved gate region; other site
1034836001092	putative PBP binding loops; other site
1034836001093	ABC-ATPase subunit interface; other site
1034836001094	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
1034836001095	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1034836001096	Walker A/P-loop; other site
1034836001097	ATP binding site [chemical binding]; other site
1034836001098	Q-loop/lid; other site
1034836001099	ABC transporter signature motif; other site
1034836001100	Walker B; other site
1034836001101	D-loop; other site
1034836001102	H-loop/switch region; other site
1034836001103	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
1034836001104	M20 Peptidase Aminoacyclase-1 YxeP-like proteins, including YxeP, YtnL, YjiB and HipO2; Region: M20_Acy1_YxeP_like; cd05669
1034836001105	metal binding site [ion binding]; metal-binding site
1034836001106	dimer interface [polypeptide binding]; other site
1034836001107	MmgE/PrpD family; Region: MmgE_PrpD; cl00912
1034836001108	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1034836001109	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1034836001110	Walker A/P-loop; other site
1034836001111	ATP binding site [chemical binding]; other site
1034836001112	Q-loop/lid; other site
1034836001113	ABC transporter signature motif; other site
1034836001114	Walker B; other site
1034836001115	D-loop; other site
1034836001116	H-loop/switch region; other site
1034836001117	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1034836001118	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
1034836001119	FtsX-like permease family; Region: FtsX; pfam02687
1034836001120	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1034836001121	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1034836001122	active site
1034836001123	phosphorylation site [posttranslational modification]
1034836001124	intermolecular recognition site; other site
1034836001125	dimerization interface [polypeptide binding]; other site
1034836001126	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1034836001127	DNA binding site [nucleotide binding]
1034836001128	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1034836001129	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1034836001130	dimerization interface [polypeptide binding]; other site
1034836001131	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1034836001132	dimer interface [polypeptide binding]; other site
1034836001133	phosphorylation site [posttranslational modification]
1034836001134	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1034836001135	ATP binding site [chemical binding]; other site
1034836001136	Mg2+ binding site [ion binding]; other site
1034836001137	G-X-G motif; other site
1034836001138	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
1034836001139	binding surface
1034836001140	TPR motif; other site
1034836001141	Tetratricopeptide repeat; Region: TPR_12; pfam13424
1034836001142	Tetratricopeptide repeat; Region: TPR_12; pfam13424
1034836001143	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1034836001144	TPR motif; other site
1034836001145	binding surface
1034836001146	Tetratricopeptide repeat; Region: TPR_12; pfam13424
1034836001147	Rap-phr extracellular signalling; Region: PhrC_PhrF; pfam11131
1034836001148	aspartate kinase; Reviewed; Region: PRK09034
1034836001149	AAK_AKiii-YclM-BS: Amino Acid Kinase Superfamily (AAK), AKiii-YclM-BS; this CD includes the N-terminal catalytic aspartokinase (AK) domain of the lysine plus threonine-sensitive aspartokinase isoenzyme AKIII, a monofunctional class enzyme found in...; Region: AAK_AKiii-YclM-BS; cd04245
1034836001150	putative catalytic residues [active]
1034836001151	putative nucleotide binding site [chemical binding]; other site
1034836001152	putative aspartate binding site [chemical binding]; other site
1034836001153	ACT domains located C-terminal to the catalytic domain of the lysine plus threonine-sensitive aspartokinase isoenzyme AKIII; Region: ACT_AKiii-YclM-BS_1; cd04911
1034836001154	allosteric regulatory residue; other site
1034836001155	ACT domains located C-terminal to the catalytic domain of the lysine plus threonine-sensitive aspartokinase isoenzyme AKIII; Region: ACT_AKiii-YclM-BS_2; cd04916
1034836001156	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
1034836001157	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1034836001158	ABC-ATPase subunit  interface; other site
1034836001159	dimer interface [polypeptide binding]; other site
1034836001160	putative PBP binding regions; other site
1034836001161	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1034836001162	ABC-ATPase subunit  interface; other site
1034836001163	dimer interface [polypeptide binding]; other site
1034836001164	putative PBP binding regions; other site
1034836001165	ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CeuD; COG4604
1034836001166	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
1034836001167	Walker A/P-loop; other site
1034836001168	ATP binding site [chemical binding]; other site
1034836001169	Q-loop/lid; other site
1034836001170	ABC transporter signature motif; other site
1034836001171	Walker B; other site
1034836001172	D-loop; other site
1034836001173	H-loop/switch region; other site
1034836001174	ABC-type enterochelin transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: CeuA; COG4607
1034836001175	Siderophore binding protein FatB.  These proteins have been shown to function as ABC-type initial receptors in the siderophore-mediated iron uptake in some eubacterial species.  They belong to the TroA superfamily of periplasmic metal binding proteins...; Region: FatB; cd01140
1034836001176	putative ligand binding residues [chemical binding]; other site
1034836001177	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1034836001178	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1034836001179	putative substrate translocation pore; other site
1034836001180	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1034836001181	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1034836001182	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1034836001183	This family contains NADPH-dependent flavin reductase and oxygen-insensitive nitroreductase. These enzymes are homodimeric flavoproteins that contain one FMN per monomer as a cofactor. Flavin reductase catalyzes the reduction of flavin by using NADPH as...; Region: NfsA_FRP; cd02146
1034836001184	dimer interface [polypeptide binding]; other site
1034836001185	FMN binding site [chemical binding]; other site
1034836001186	NADPH bind site [chemical binding]; other site
1034836001187	Uncharacterized conserved protein [Function unknown]; Region: COG1359
1034836001188	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1034836001189	dimerization interface [polypeptide binding]; other site
1034836001190	putative DNA binding site [nucleotide binding]; other site
1034836001191	putative Zn2+ binding site [ion binding]; other site
1034836001192	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
1034836001193	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1034836001194	DNA-binding site [nucleotide binding]; DNA binding site
1034836001195	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1034836001196	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1034836001197	homodimer interface [polypeptide binding]; other site
1034836001198	catalytic residue [active]
1034836001199	4-aminobutyrate aminotransferase; Reviewed; Region: PRK06918
1034836001200	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1034836001201	inhibitor-cofactor binding pocket; inhibition site
1034836001202	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1034836001203	catalytic residue [active]
1034836001204	succinic semialdehyde dehydrogenase; Region: PLN02278
1034836001205	Mitochondrial succinate-semialdehyde dehydrogenase and ALDH family members 5A1 and 5F1-like; Region: ALDH_F5_SSADH_GabD; cd07103
1034836001206	tetramerization interface [polypeptide binding]; other site
1034836001207	NAD(P) binding site [chemical binding]; other site
1034836001208	catalytic residues [active]
1034836001209	Putative glucose uptake permease [Carbohydrate transport and metabolism]; Region: GlcU; COG4975
1034836001210	L-rhamnose-proton symport protein (RhaT); Region: RhaT; cl05728
1034836001211	glucose-1-dehydrogenase; Provisional; Region: PRK08936
1034836001212	glucose 1 dehydrogenase (GlcDH), classical (c) SDRs; Region: GlcDH_SDR_c; cd05358
1034836001213	NAD binding site [chemical binding]; other site
1034836001214	homodimer interface [polypeptide binding]; other site
1034836001215	active site
1034836001216	Reeler-like domain of YcnI and similar proteins; Region: YcnI_like; cd08545
1034836001217	Uncharacterized protein, homolog of Cu resistance protein CopC [General function prediction only]; Region: CopC; COG2372
1034836001218	Putative copper export protein [Inorganic ion transport and metabolism]; Region: PcoD; COG1276
1034836001219	YtkA-like; Region: YtkA; pfam13115
1034836001220	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1034836001221	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
1034836001222	Phosphotransferase system, mannitol-specific IIBC component [Carbohydrate transport and metabolism]; Region: MtlA; COG2213
1034836001223	PTS system, mannitol-specific IIC component; Region: mtlA; TIGR00851
1034836001224	PTS_IIB_mannitol: subunit IIB of enzyme II (EII) of the mannitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is a mannitol-specific permease with two cytoplasmic domains (IIA and IIB) and a transmembrane...; Region: PTS_IIB_mannitol; cd05567
1034836001225	active site
1034836001226	P-loop; other site
1034836001227	phosphorylation site [posttranslational modification]
1034836001228	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1034836001229	active site
1034836001230	phosphorylation site [posttranslational modification]
1034836001231	mannitol-1-phosphate 5-dehydrogenase; Provisional; Region: PRK02318
1034836001232	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
1034836001233	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
1034836001234	FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid...; Region: FabZ; cd01288
1034836001235	Predicted hydrolases of the HAD superfamily [General function prediction only]; Region: Cof; COG0561
1034836001236	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1034836001237	active site
1034836001238	motif I; other site
1034836001239	motif II; other site
1034836001240	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1034836001241	LamB/YcsF family of  lactam utilization protein; Region: LamB_YcsF_like; cd10787
1034836001242	putative active site [active]
1034836001243	Mn2+ and Fe2+ transporters of the NRAMP family [Inorganic ion transport and metabolism]; Region: MntH; COG1914
1034836001244	hypothetical protein; Provisional; Region: PRK05463
1034836001245	Allophanate hydrolase subunit 1 [Amino acid transport and metabolism]; Region: DUR1; COG2049
1034836001246	Allophanate hydrolase subunit 1; Region: AHS1; pfam02682
1034836001247	Allophanate hydrolase subunit 2 [Amino acid transport and metabolism]; Region: DUR1; COG1984
1034836001248	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
1034836001249	Transcriptional regulator [Transcription]; Region: IclR; COG1414
1034836001250	Bacterial transcriptional regulator; Region: IclR; pfam01614
1034836001251	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cl01053
1034836001252	active site
1034836001253	catalytic triad [active]
1034836001254	oxyanion hole [active]
1034836001255	Protein of unknown function (DUF3953); Region: DUF3953; pfam13129
1034836001256	Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides [General function prediction only]; Region: COG2329
1034836001257	NTF2-like N-terminal transpeptidase domain; Region: MecA_N; pfam05223
1034836001258	Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane]; Region: FtsI; COG0768
1034836001259	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
1034836001260	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
1034836001261	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1034836001262	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1034836001263	active site
1034836001264	catalytic tetrad [active]
1034836001265	Transcriptional antiterminator [Transcription]; Region: BglG; COG3711
1034836001266	HTH domain; Region: HTH_11; pfam08279
1034836001267	HTH domain; Region: HTH_11; cl17392
1034836001268	PRD domain; Region: PRD; pfam00874
1034836001269	PRD domain; Region: PRD; pfam00874
1034836001270	PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568
1034836001271	active site
1034836001272	P-loop; other site
1034836001273	phosphorylation site [posttranslational modification]
1034836001274	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cl00163
1034836001275	Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: CaiC; COG0318
1034836001276	Prokaryotic long-chain fatty acid CoA synthetases similar to Escherichia coli FadD; Region: FC-FACS_FadD_like; cd05936
1034836001277	acyl-activating enzyme (AAE) consensus motif; other site
1034836001278	putative AMP binding site [chemical binding]; other site
1034836001279	putative active site [active]
1034836001280	putative CoA binding site [chemical binding]; other site
1034836001281	short chain dehydrogenase; Provisional; Region: PRK06701
1034836001282	classical (c) SDR, subgroup 1; Region: SDR_c1; cd05355
1034836001283	NAD binding site [chemical binding]; other site
1034836001284	metal binding site [ion binding]; metal-binding site
1034836001285	active site
1034836001286	Protein of unknown function (DUF1498); Region: DUF1498; cl17840
1034836001287	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
1034836001288	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
1034836001289	Uncharacterized stress protein (general stress protein 26) [General function prediction only]; Region: COG3871
1034836001290	Pyridoxamine 5'-phosphate oxidase; Region: Pyridox_oxidase; pfam01243
1034836001291	Protein of unknown function (DUF2837); Region: DUF2837; pfam10997
1034836001292	Domain of unknown function (DUF3817); Region: DUF3817; pfam12823
1034836001293	helix_turn_helix ASNC type; Region: HTH_ASNC; smart00344
1034836001294	AsnC-type helix-turn-helix domain; Region: HTH_AsnC-type; pfam13404
1034836001295	putative DNA binding site [nucleotide binding]; other site
1034836001296	putative Zn2+ binding site [ion binding]; other site
1034836001297	AsnC family; Region: AsnC_trans_reg; pfam01037
1034836001298	DNA topoisomerase III; Provisional; Region: PRK07726
1034836001299	TOPRIM_TopoIA_TopoIII: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to topoisomerase III. Type IA DNA topoisomerases remove (relax) negative supercoils in the DNA by: cleaving...; Region: TOPRIM_TopoIA_TopoIII; cd03362
1034836001300	active site
1034836001301	putative interdomain interaction site [polypeptide binding]; other site
1034836001302	putative metal-binding site [ion binding]; other site
1034836001303	putative nucleotide binding site [chemical binding]; other site
1034836001304	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
1034836001305	domain I; other site
1034836001306	DNA binding groove [nucleotide binding]
1034836001307	phosphate binding site [ion binding]; other site
1034836001308	domain II; other site
1034836001309	domain III; other site
1034836001310	nucleotide binding site [chemical binding]; other site
1034836001311	catalytic site [active]
1034836001312	domain IV; other site
1034836001313	Zn-finger domain associated with topoisomerase type I [DNA replication, recombination, and repair]; Region: TopA; COG0551
1034836001314	RNA polymerases M/15 Kd subunit; Region: RNA_POL_M_15KD; cl02717
1034836001315	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1034836001316	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1034836001317	metal binding site [ion binding]; metal-binding site
1034836001318	active site
1034836001319	I-site; other site
1034836001320	Putative NodB-like catalytic domain of uncharacterized proteins found in bacteria; Region: CE4_COG5298; cd10923
1034836001321	Uncharacterized protein conserved in bacteria (DUF2334); Region: DUF2334; pfam10096
1034836001322	NodB motif; other site
1034836001323	putative active site [active]
1034836001324	putative catalytic site [active]
1034836001325	putative Zn binding site [ion binding]; other site
1034836001326	potential frameshift: common BLAST hit: gi|308172288|ref|YP_003918993.1| glycosyltransferase associated to biofilm formation
1034836001327	Bacterial cellulose synthase subunit; Region: BcsB; cl15851
1034836001328	Amino acid permease; Region: AA_permease_2; pfam13520
1034836001329	pyruvate oxidase; Provisional; Region: PRK08611
1034836001330	Pyrimidine (PYR) binding domain of POX; Region: TPP_PYR_POX; cd07039
1034836001331	PYR/PP interface [polypeptide binding]; other site
1034836001332	dimer interface [polypeptide binding]; other site
1034836001333	tetramer interface [polypeptide binding]; other site
1034836001334	TPP binding site [chemical binding]; other site
1034836001335	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1034836001336	Thiamine pyrophosphate (TPP) family, Pyruvate oxidase (POX) subfamily, TPP-binding module; composed of proteins similar to Lactobacillus plantarum POX, which plays a key role in controlling acetate production under aerobic conditions. POX decarboxylates...; Region: TPP_POX; cd02014
1034836001337	TPP-binding site [chemical binding]; other site
1034836001338	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
1034836001339	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1034836001340	Coenzyme A binding pocket [chemical binding]; other site
1034836001341	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cl00107
1034836001342	Uncharacterized distant relative of cell wall-associated hydrolases [Function unknown]; Region: COG3863
1034836001343	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
1034836001344	binding surface
1034836001345	TPR motif; other site
1034836001346	Tetratricopeptide repeat; Region: TPR_12; pfam13424
1034836001347	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
1034836001348	TPR motif; other site
1034836001349	binding surface
1034836001350	Tetratricopeptide repeat; Region: TPR_12; pfam13424
1034836001351	Spore germination protein gerPA/gerPF; Region: gerPA; pfam10676
1034836001352	manganese transport protein MntH; Reviewed; Region: PRK00701
1034836001353	Natural resistance-associated macrophage protein; Region: Nramp; pfam01566
1034836001354	Bacterial SH3 domain; Region: SH3_3; cl17532
1034836001355	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4876
1034836001356	Membrane transporters of cations and cationic drugs [Inorganic ion transport and metabolism]; Region: EmrE; COG2076
1034836001357	EcsC protein family; Region: EcsC; pfam12787
1034836001358	General stress protein [General function prediction only]; Region: GsiB; COG3729
1034836001359	General stress protein [General function prediction only]; Region: GsiB; COG3729
1034836001360	Mannose-6-phosphate isomerase [Carbohydrate transport and metabolism]; Region: {ManC}; COG0662
1034836001361	Manganese catalase, ferritin-like diiron-binding domain; Region: Mn_catalase; cd01051
1034836001362	dimanganese center [ion binding]; other site
1034836001363	TRAP-type C4-dicarboxylate transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: DctP; COG1638
1034836001364	tripartite ATP-independent periplasmic transporter solute receptor, DctP family; Region: dctP; TIGR00787
1034836001365	Signal transduction histidine kinase regulating citrate/malate metabolism [Signal transduction mechanisms]; Region: CitA; COG3290
1034836001366	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1034836001367	putative active site [active]
1034836001368	heme pocket [chemical binding]; other site
1034836001369	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1034836001370	ATP binding site [chemical binding]; other site
1034836001371	Mg2+ binding site [ion binding]; other site
1034836001372	G-X-G motif; other site
1034836001373	Response regulator of citrate/malate metabolism [Transcription / Signal transduction mechanisms]; Region: CitB; COG4565
1034836001374	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1034836001375	active site
1034836001376	phosphorylation site [posttranslational modification]
1034836001377	intermolecular recognition site; other site
1034836001378	dimerization interface [polypeptide binding]; other site
1034836001379	HTH domain; Region: HTH_11; pfam08279
1034836001380	C4-dicarboxylate transporter DctA; Reviewed; Region: PRK01663
1034836001381	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
1034836001382	Domain of unknown function DUF20; Region: UPF0118; pfam01594
1034836001383	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
1034836001384	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
1034836001385	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1034836001386	Walker A/P-loop; other site
1034836001387	ATP binding site [chemical binding]; other site
1034836001388	Q-loop/lid; other site
1034836001389	ABC transporter signature motif; other site
1034836001390	Walker B; other site
1034836001391	D-loop; other site
1034836001392	H-loop/switch region; other site
1034836001393	ABC-2 family transporter protein; Region: ABC2_membrane_2; pfam12679
1034836001394	ABC-2 family transporter protein; Region: ABC2_membrane_4; pfam12730
1034836001395	Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960
1034836001396	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
1034836001397	active site
1034836001398	Protein of unknown function (DUF3901); Region: DUF3901; pfam13040
1034836001399	Protein of unknown function (DUF3940); Region: DUF3940; pfam13076
1034836001400	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
1034836001401	cation diffusion facilitator family transporter; Region: CDF; TIGR01297
1034836001402	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
1034836001403	catalytic residues [active]
1034836001404	D-alanyl-alanine synthetase A; Reviewed; Region: ddl; PRK01966
1034836001405	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
1034836001406	D-ala D-ala ligase C-terminus; Region: Dala_Dala_lig_C; pfam07478
1034836001407	UDP-N-acetylmuramyl pentapeptide synthase [Cell envelope biogenesis, outer membrane]; Region: MurF; COG0770
1034836001408	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1034836001409	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1034836001410	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1034836001411	helicase 45; Provisional; Region: PTZ00424
1034836001412	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
1034836001413	ATP binding site [chemical binding]; other site
1034836001414	Mg++ binding site [ion binding]; other site
1034836001415	motif III; other site
1034836001416	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1034836001417	nucleotide binding region [chemical binding]; other site
1034836001418	ATP-binding site [chemical binding]; other site
1034836001419	Uncharacterized conserved protein [Function unknown]; Region: COG3402
1034836001420	Predicted membrane protein [Function unknown]; Region: COG3428
1034836001421	Bacterial PH domain; Region: DUF304; pfam03703
1034836001422	Bacterial PH domain; Region: DUF304; pfam03703
1034836001423	Bacterial PH domain; Region: DUF304; pfam03703
1034836001424	Rhomboid family; Region: Rhomboid; pfam01694
1034836001425	4'-phosphopantetheinyl transferase; Provisional; Region: acpS; PRK00070
1034836001426	Outer membrane lipoprotein-sorting protein [Cell envelope biogenesis, outer membrane]; Region: LolA; COG2834
1034836001427	alanine racemase; Region: alr; TIGR00492
1034836001428	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Alanine Racemase; Region: PLPDE_III_AR; cd00430
1034836001429	active site
1034836001430	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1034836001431	dimer interface [polypeptide binding]; other site
1034836001432	substrate binding site [chemical binding]; other site
1034836001433	catalytic residues [active]
1034836001434	Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain and a metal-binding domain [Transcription]; Region: NikR; COG0864
1034836001435	ribbon-helix-helix domain containing protein; Region: PHA00617
1034836001436	Growth inhibitor [Signal transduction mechanisms]; Region: MazF; COG2337
1034836001437	Rsbr N terminal; Region: Rsbr_N; pfam08678
1034836001438	Sulphate Transporter and Anti-Sigma factor antagonist domain of the "stressosome" complex proteins RsbS and RsbR, regulators of the bacterial stress activated alternative sigma factor sigma-B by phosphorylation; Region: STAS_RsbR_RsbS_like; cd07041
1034836001439	Sulphate Transporter and Anti-Sigma factor antagonist domain of the "stressosome" complex proteins RsbS and RsbR, regulators of the bacterial stress activated alternative sigma factor sigma-B by phosphorylation; Region: STAS_RsbR_RsbS_like; cd07041
1034836001440	Anti-sigma regulatory factor (Ser/Thr protein kinase) [Signal transduction mechanisms]; Region: RsbW; COG2172
1034836001441	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1034836001442	ATP binding site [chemical binding]; other site
1034836001443	Mg2+ binding site [ion binding]; other site
1034836001444	G-X-G motif; other site
1034836001445	Serine phosphatase RsbU, regulator of sigma subunit [Signal transduction mechanisms / Transcription]; Region: RsbU; COG2208
1034836001446	Phosphoserine phosphatase RsbU, N-terminal domain; Region: RsbU_N; pfam08673
1034836001447	Stage II sporulation protein E (SpoIIE); Region: SpoIIE; pfam07228
1034836001448	Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation; Region: STAS_anti-anti-sigma_factors; cd07043
1034836001449	anti sigma factor interaction site; other site
1034836001450	regulatory phosphorylation site [posttranslational modification]; other site
1034836001451	Anti-sigma regulatory factor (Ser/Thr protein kinase) [Signal transduction mechanisms]; Region: RsbW; COG2172
1034836001452	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1034836001453	ATP binding site [chemical binding]; other site
1034836001454	Mg2+ binding site [ion binding]; other site
1034836001455	G-X-G motif; other site
1034836001456	RNA polymerase sigma factor SigB; Validated; Region: PRK08583
1034836001457	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1034836001458	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
1034836001459	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1034836001460	DNA binding residues [nucleotide binding]
1034836001461	Sigma factor PP2C-like phosphatases; Region: PP2C_SIG; smart00331
1034836001462	Transcriptional accessory protein [Transcription]; Region: Tex; COG2183
1034836001463	Tex-like protein N-terminal domain; Region: Tex_N; pfam09371
1034836001464	Likely ribonuclease with RNase H fold; Region: YqgFc; smart00732
1034836001465	S1_Tex: The C-terminal S1 domain of a transcription accessory factor called Tex, which has been characterized in Bordetella pertussis and Pseudomonas aeruginosa. The tex gene is essential in Bortella pertusis and is named for its role in toxin expression; Region: S1_Tex; cd05685
1034836001466	RNA binding site [nucleotide binding]; other site
1034836001467	Zn-dependent metalloprotease, SprT family [General function prediction only]; Region: SprT; COG3091
1034836001468	hypothetical protein; Provisional; Region: PRK04351
1034836001469	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cd00312
1034836001470	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
1034836001471	substrate binding pocket [chemical binding]; other site
1034836001472	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1034836001473	peroxiredoxin, Ohr subfamily; Region: organ_hyd_perox; TIGR03561
1034836001474	Transcriptional regulators [Transcription]; Region: MarR; COG1846
1034836001475	MarR family; Region: MarR; pfam01047
1034836001476	Domain of unknown function (DUF4367); Region: DUF4367; pfam14285
1034836001477	Transcriptional regulators [Transcription]; Region: MarR; COG1846
1034836001478	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1034836001479	dimerization interface [polypeptide binding]; other site
1034836001480	putative Zn2+ binding site [ion binding]; other site
1034836001481	putative DNA binding site [nucleotide binding]; other site
1034836001482	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1034836001483	Coenzyme A binding pocket [chemical binding]; other site
1034836001484	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1034836001485	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1034836001486	putative substrate translocation pore; other site
1034836001487	Glycosyl hydrolase family 26; Region: Glyco_hydro_26; pfam02156
1034836001488	Replication initiation factor; Region: Rep_trans; pfam02486
1034836001489	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
1034836001490	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1034836001491	DNA-binding site [nucleotide binding]; DNA binding site
1034836001492	RNA-binding motif; other site
1034836001493	Asp/Glu/Hydantoin racemase; Region: Asp_Glu_race; cl00518
1034836001494	aspartate racemase; Region: asp_race; TIGR00035
1034836001495	Protein of unknown function (DUF2812); Region: DUF2812; pfam11193
1034836001496	Predicted transcriptional regulators [Transcription]; Region: COG1695
1034836001497	Transcriptional regulator PadR-like family; Region: PadR; cl17335
1034836001498	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
1034836001499	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1034836001500	DNA-binding site [nucleotide binding]; DNA binding site
1034836001501	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1034836001502	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1034836001503	homodimer interface [polypeptide binding]; other site
1034836001504	catalytic residue [active]
1034836001505	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1034836001506	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1034836001507	putative substrate translocation pore; other site
1034836001508	Patatin [General function prediction only]; Region: COG3621
1034836001509	Patatin-like phospholipase; Region: Pat17_PNPLA8_PNPLA9_like1; cd07213
1034836001510	active site
1034836001511	nucleophile elbow; other site
1034836001512	FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277
1034836001513	FAD binding domain; Region: FAD_binding_4; pfam01565
1034836001514	Berberine and berberine like; Region: BBE; pfam08031
1034836001515	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_10; cd07251
1034836001516	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1034836001517	Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism]; Region: CzcD; COG1230
1034836001518	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
1034836001519	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1034836001520	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
1034836001521	Mannose-6-phosphate isomerase [Carbohydrate transport and metabolism]; Region: {ManC}; COG0662
1034836001522	Histone acetyltransferase HPA2 and related acetyltransferases [Transcription / General function prediction only]; Region: WecD; COG0454
1034836001523	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1034836001524	Coenzyme A binding pocket [chemical binding]; other site
1034836001525	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1034836001526	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3708
1034836001527	chloramphenicol/florfenicol resistance protein; Provisional; Region: PRK14453
1034836001528	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1034836001529	FeS/SAM binding site; other site
1034836001530	Arsenite efflux pump ACR3 and related permeases [Inorganic ion transport and metabolism]; Region: ACR3; COG0798
1034836001531	Sodium Bile acid symporter family; Region: SBF; cl17470
1034836001532	Zn-dependent alcohol dehydrogenases [General function prediction only]; Region: AdhP; COG1064
1034836001533	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD1; cd05283
1034836001534	putative NAD(P) binding site [chemical binding]; other site
1034836001535	putative substrate binding site [chemical binding]; other site
1034836001536	catalytic Zn binding site [ion binding]; other site
1034836001537	structural Zn binding site [ion binding]; other site
1034836001538	dimer interface [polypeptide binding]; other site
1034836001539	Predicted transcriptional regulators [Transcription]; Region: SoxR; COG0789
1034836001540	Helix-Turn-Helix DNA binding domain of the MerR-like transcription regulators YyaN and YraB; Region: HTH_YyaN; cd01109
1034836001541	DNA binding residues [nucleotide binding]
1034836001542	putative dimer interface [polypeptide binding]; other site
1034836001543	Na+/H+ antiporter family; Region: Na_H_antiporter; pfam03553
1034836001544	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
1034836001545	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1034836001546	DNA-binding site [nucleotide binding]; DNA binding site
1034836001547	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1034836001548	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1034836001549	homodimer interface [polypeptide binding]; other site
1034836001550	catalytic residue [active]
1034836001551	Putative FMN-binding domain; Region: FMN_bind_2; pfam04299
1034836001552	benzoate transport; Region: 2A0115; TIGR00895
1034836001553	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1034836001554	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1034836001555	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
1034836001556	EamA-like transporter family; Region: EamA; cl17759
1034836001557	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
1034836001558	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1034836001559	DNA-binding site [nucleotide binding]; DNA binding site
1034836001560	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1034836001561	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1034836001562	homodimer interface [polypeptide binding]; other site
1034836001563	catalytic residue [active]
1034836001564	Spore coat protein [Cell envelope biogenesis, outer membrane]; Region: COG5577
1034836001565	Glutathione-dependent formaldehyde dehydrogenase related proteins, child 1; Region: FDH_like_1; cd08283
1034836001566	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
1034836001567	NAD binding site [chemical binding]; other site
1034836001568	catalytic Zn binding site [ion binding]; other site
1034836001569	structural Zn binding site [ion binding]; other site
1034836001570	Spore coat protein [Cell envelope biogenesis, outer membrane]; Region: COG5577
1034836001571	Predicted drug exporters of the RND superfamily [General function prediction only]; Region: COG2409
1034836001572	Predicted glutamine amidotransferases [General function prediction only]; Region: COG2071
1034836001573	Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain; Region: GATase1_2; cd01745
1034836001574	catalytic triad [active]
1034836001575	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
1034836001576	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1034836001577	ABC transporter; Region: ABC_tran_2; pfam12848
1034836001578	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1034836001579	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
1034836001580	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1034836001581	Coenzyme A binding pocket [chemical binding]; other site
1034836001582	Uncharacterized conserved protein [Function unknown]; Region: COG1284
1034836001583	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
1034836001584	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
1034836001585	Uncharacterized protein conserved in bacteria (DUF2179); Region: DUF2179; pfam10035
1034836001586	Iron-containing alcohol dehydrogenase; Region: Fe-ADH; pfam00465
1034836001587	Glycerol dehydrogenases (GlyDH) catalyzes oxidation of glycerol to dihydroxyacetone in glycerol dissmilation; Region: GlyDH; cd08170
1034836001588	dimer interface [polypeptide binding]; other site
1034836001589	active site
1034836001590	metal binding site [ion binding]; metal-binding site
1034836001591	drug resistance transporter, Bcr/CflA subfamily; Region: efflux_Bcr_CflA; TIGR00710
1034836001592	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1034836001593	putative substrate translocation pore; other site
1034836001594	beta-ketoacyl-acyl-carrier-protein synthase II; Region: fabF; TIGR03150
1034836001595	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
1034836001596	dimer interface [polypeptide binding]; other site
1034836001597	active site
1034836001598	Helix-turn-helix domain; Region: HTH_31; pfam13560
1034836001599	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
1034836001600	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1034836001601	Coenzyme A binding pocket [chemical binding]; other site
1034836001602	Helix-Turn-Helix DNA binding domain of the BltR transcription regulator; Region: HTH_BltR; cd04782
1034836001603	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
1034836001604	DNA binding residues [nucleotide binding]
1034836001605	Transcriptional regulator, effector-binding domain/component [Transcription / Signal transduction mechanisms]; Region: COG4978
1034836001606	EamA-like transporter family; Region: EamA; pfam00892
1034836001607	EamA-like transporter family; Region: EamA; pfam00892
1034836001608	Hydrolase of X-linked nucleoside diphosphate N terminal; Region: Nudix_N; pfam12535
1034836001609	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_14; cd04672
1034836001610	nudix motif; other site
1034836001611	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
1034836001612	Epoxide hydrolase N terminus; Region: EHN; pfam06441
1034836001613	Isocitrate/isopropylmalate dehydrogenase [Amino acid transport and metabolism]; Region: LeuB; COG0473
1034836001614	tartrate dehydrogenase; Provisional; Region: PRK08194
1034836001615	Transcriptional regulators [Transcription]; Region: GntR; COG1802
1034836001616	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1034836001617	DNA-binding site [nucleotide binding]; DNA binding site
1034836001618	FCD domain; Region: FCD; pfam07729
1034836001619	This family includes the Gtfs, a group of homologous glycosyltransferases involved in the final stages of the biosynthesis of antibiotics vancomycin and related chloroeremomycin. Gtfs transfer sugar moieties from an activated NDP-sugar donor to the...; Region: GT1_Gtf_like; cd03784
1034836001620	glycosyltransferase, MGT family; Region: MGT; TIGR01426
1034836001621	active site
1034836001622	TDP-binding site; other site
1034836001623	acceptor substrate-binding pocket; other site
1034836001624	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
1034836001625	Beta-lactamase; Region: Beta-lactamase; pfam00144
1034836001626	Domain of unknown function (DUF3471); Region: DUF3471; pfam11954
1034836001627	Protein of unknown function (DUF1541); Region: DUF1541; pfam07563
1034836001628	Protein of unknown function (DUF1541); Region: DUF1541; pfam07563
1034836001629	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
1034836001630	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1034836001631	putative substrate translocation pore; other site
1034836001632	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
1034836001633	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1034836001634	DNA-binding site [nucleotide binding]; DNA binding site
1034836001635	The UbiC transcription regulator-associated (UTRA) domain is a conserved ligand-binding domain; Region: UTRA; smart00866
1034836001636	Transcriptional regulators [Transcription]; Region: FadR; COG2186
1034836001637	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1034836001638	DNA-binding site [nucleotide binding]; DNA binding site
1034836001639	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
1034836001640	Cyanate permease [Inorganic ion transport and metabolism]; Region: CynX; COG2807
1034836001641	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1034836001642	putative substrate translocation pore; other site
1034836001643	Membrane transporters of cations and cationic drugs [Inorganic ion transport and metabolism]; Region: EmrE; COG2076
1034836001644	Membrane transporters of cations and cationic drugs [Inorganic ion transport and metabolism]; Region: EmrE; COG2076
1034836001645	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1034836001646	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1034836001647	amino acid transporter; Region: 2A0306; TIGR00909
1034836001648	Manganese catalase, ferritin-like diiron-binding domain; Region: Mn_catalase; cd01051
1034836001649	dimanganese center [ion binding]; other site
1034836001650	Putative hydrophobic ligand-binding SRPBCC domain of Micromonospora echinospora CalC, human Aha1, and related proteins; Region: SRPBCC_CalC_Aha1-like; cd07814
1034836001651	putative hydrophobic ligand binding site [chemical binding]; other site
1034836001652	Yhfp putative quinone oxidoreductases; Region: MDR_yhfp_like; cd08289
1034836001653	putative quinone oxidoreductase, YhdH/YhfP family; Region: oxido_YhdH; TIGR02823
1034836001654	putative NADP binding site [chemical binding]; other site
1034836001655	putative dimer interface [polypeptide binding]; other site
1034836001656	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1034836001657	Sugar (and other) transporter; Region: Sugar_tr; pfam00083
1034836001658	putative substrate translocation pore; other site
1034836001659	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1034836001660	thiamine monophosphate kinase; Provisional; Region: PRK05731
1034836001661	ThiL (Thiamine-monophosphate kinase) plays a dual role in de novo biosynthesis and in salvage of exogenous thiamine. Thiamine salvage occurs in two steps, with thiamine kinase catalyzing the formation of thiamine phosphate, and ThiL catalyzing the...; Region: ThiL; cd02194
1034836001662	ATP binding site [chemical binding]; other site
1034836001663	dimerization interface [polypeptide binding]; other site
1034836001664	Predicted ATPase or kinase [General function prediction only]; Region: COG0802
1034836001665	tRNA threonylcarbamoyl adenosine modification protein YeaZ; Region: T6A_YeaZ; TIGR03725
1034836001666	Glycoprotease family; Region: Peptidase_M22; pfam00814
1034836001667	ribosomal-protein-alanine acetyltransferase; Region: rimI; TIGR01575
1034836001668	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1034836001669	Coenzyme A binding pocket [chemical binding]; other site
1034836001670	UGMP family protein; Validated; Region: PRK09604
1034836001671	tRNA threonylcarbamoyl adenosine modification protein YeaZ; Region: T6A_YeaZ; TIGR03725
1034836001672	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
1034836001673	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
1034836001674	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1034836001675	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1034836001676	ABC transporter; Region: ABC_tran_2; pfam12848
1034836001677	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1034836001678	ABC transporter; Region: ABC_tran_2; pfam12848
1034836001679	MoaC family, prokaryotic and eukaryotic. Members of this family are involved in molybdenum cofactor (Moco) biosynthesis, an essential cofactor of a diverse group of redox enzymes. MoaC, a small hexameric protein, converts, together with MoaA, a guanosine...; Region: MoaC_PE; cd01420
1034836001680	trimer interface [polypeptide binding]; other site
1034836001681	dimer interface [polypeptide binding]; other site
1034836001682	putative active site [active]
1034836001683	redox-sensing transcriptional repressor Rex; Provisional; Region: PRK05472
1034836001684	Putative DNA-binding protein N-terminus; Region: Put_DNA-bind_N; pfam06971
1034836001685	CoA binding domain; Region: CoA_binding; pfam02629
1034836001686	twin arginine translocase protein A; Provisional; Region: tatA; PRK14861
1034836001687	Sec-independent protein secretion pathway component TatC [Intracellular trafficking and secretion]; Region: TatC; COG0805
1034836001688	Domain of unknown function (DUF4305); Region: DUF4305; pfam14146
1034836001689	CAAX protease self-immunity; Region: Abi; pfam02517
1034836001690	Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320
1034836001691	oligomerisation interface [polypeptide binding]; other site
1034836001692	mobile loop; other site
1034836001693	roof hairpin; other site
1034836001694	chaperonin GroEL; Reviewed; Region: groEL; PRK12849
1034836001695	GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344
1034836001696	ring oligomerisation interface [polypeptide binding]; other site
1034836001697	ATP/Mg binding site [chemical binding]; other site
1034836001698	stacking interactions; other site
1034836001699	hinge regions; other site
1034836001700	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
1034836001701	Putative peptidoglycan-binding domain-containing protein [Cell envelope biogenesis, outer membrane]; Region: COG3409
1034836001702	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
1034836001703	BacA is a bacterial lysin from Enterococcus faecalis that degrades bacterial cell walls by catalyzing the hydrolysis of 1,4-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues. BacA is homologous to the YbfG and YkuG lysins of...; Region: GH25_BacA-like; cd06418
1034836001704	active site
1034836001705	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1034836001706	Walker A motif; other site
1034836001707	ATP binding site [chemical binding]; other site
1034836001708	Walker B motif; other site
1034836001709	Tetratricopeptide repeat; Region: TPR_12; pfam13424
1034836001710	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1034836001711	binding surface
1034836001712	TPR motif; other site
1034836001713	TPR repeat; Region: TPR_11; pfam13414
1034836001714	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
1034836001715	Sorbitol dehydrogenase; Region: sorbitol_DH; cd05285
1034836001716	inhibitor binding site; inhibition site
1034836001717	catalytic Zn binding site [ion binding]; other site
1034836001718	structural Zn binding site [ion binding]; other site
1034836001719	NADP binding site [chemical binding]; other site
1034836001720	tetramer interface [polypeptide binding]; other site
1034836001721	sugar (Glycoside-Pentoside-Hexuronide) transporter; Region: gph; TIGR00792
1034836001722	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1034836001723	putative substrate translocation pore; other site
1034836001724	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1034836001725	Fructokinases (FRKs) mainly from bacteria and plants are enzymes with high specificity for fructose, as are all FRKs, but they catalyzes the conversion of fructose to fructose-6-phosphate, which is an entry point into glycolysis via conversion into...; Region: bac_FRK; cd01167
1034836001726	putative substrate binding site [chemical binding]; other site
1034836001727	putative ATP binding site [chemical binding]; other site
1034836001728	Domain of unknown function (DUF4306); Region: DUF4306; pfam14154
1034836001729	Phage shock protein A (IM30), suppresses sigma54-dependent transcription [Transcription / Signal transduction mechanisms]; Region: PspA; COG1842
1034836001730	TFIIB zinc-binding; Region: TF_Zn_Ribbon; pfam08271
1034836001731	Beta-propeller domains of methanol dehydrogenase type [General function prediction only]; Region: COG1512
1034836001732	Repair protein; Region: Repair_PSII; pfam04536
1034836001733	Membrane protease subunit, stomatin/prohibitin family [Amino acid    transport and metabolism]; Region: COG4260
1034836001734	A subgroup of the band 7 domain of flotillin (reggie) like proteins. This subgroup contains proteins similar to stomatin, prohibitin, flotillin, HlfK/C and podicin.  Many of these band 7 domain-containing proteins are lipid raft-associated.  Individual...; Region: Band_7_5; cd03408
1034836001735	zinc-ribbon domain; Region: zf-ribbon_3; pfam13248
1034836001736	Predicted acyltransferases [Lipid metabolism]; Region: COG1835
1034836001737	Protein of unknown function (DUF1624); Region: DUF1624; cl01394
1034836001738	Protein of unknown function (DUF1510); Region: DUF1510; pfam07423
1034836001739	yrhL-like subfamily of SGNH-hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase_yrhL_like; cd01840
1034836001740	catalytic triad [active]
1034836001741	catalytic triad [active]
1034836001742	oxyanion hole [active]
1034836001743	Domain of unknown function (DUF4163); Region: DUF4163; pfam13739
1034836001744	Protein of unknown function (DUF3298); Region: DUF3298; pfam11738
1034836001745	RNA polymerase sigma-70 factor, TIGR02954 family; Region: Sig70_famx3
1034836001746	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1034836001747	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1034836001748	DNA binding residues [nucleotide binding]
1034836001749	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
1034836001750	(2R,3R)-2,3-butanediol dehydrogenase; Region: butanediol_DH_like; cd08233
1034836001751	putative NAD(P) binding site [chemical binding]; other site
1034836001752	catalytic Zn binding site [ion binding]; other site
1034836001753	Rare lipoprotein A (RlpA)-like double-psi beta-barrel; Region: DPBB_1; cl04011
1034836001754	tol-pal system beta propeller repeat protein TolB; Region: propeller_TolB; TIGR02800
1034836001755	Cold-inducible protein YdjO; Region: YdjO; pfam14169
1034836001756	Putative multicopper oxidases [Secondary metabolites biosynthesis, transport, and catabolism]; Region: SufI; COG2132
1034836001757	Multicopper oxidase; Region: Cu-oxidase_3; pfam07732
1034836001758	Multicopper oxidase; Region: Cu-oxidase; pfam00394
1034836001759	Multicopper oxidase; Region: Cu-oxidase_2; pfam07731
1034836001760	gamma-aminobutyrate permease; Region: GABAperm; TIGR01773
1034836001761	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
1034836001762	cation diffusion facilitator family transporter; Region: CDF; TIGR01297
1034836001763	MoxR-like ATPases [General function prediction only]; Region: COG0714
1034836001764	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1034836001765	Walker A motif; other site
1034836001766	ATP binding site [chemical binding]; other site
1034836001767	Walker B motif; other site
1034836001768	arginine finger; other site
1034836001769	Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) [General function prediction only]; Region: COG1721
1034836001770	Protein of unknown function DUF58; Region: DUF58; pfam01882
1034836001771	Transglutaminase-like enzymes, putative cysteine proteases [Amino acid transport and metabolism]; Region: COG1305
1034836001772	Transglutaminase-like superfamily; Region: Transglut_core; pfam01841
1034836001773	Domain of unknown function (DUF4129); Region: DUF4129; pfam13559
1034836001774	GMP synthase; Reviewed; Region: guaA; PRK00074
1034836001775	Type 1 glutamine amidotransferase (GATase1) domain found in GMP synthetase; Region: GATase1_GMP_Synthase; cd01742
1034836001776	AMP/PPi binding site [chemical binding]; other site
1034836001777	candidate oxyanion hole; other site
1034836001778	catalytic triad [active]
1034836001779	potential glutamine specificity residues [chemical binding]; other site
1034836001780	The C-terminal domain of GMP synthetase. It contains two subdomains; the ATP pyrophosphatase domain which closes to the N-termial and the dimerization domain at C-terminal end. The ATP-PPase is a twisted, five-stranded parallel beta-sheet sandwiched...; Region: GMP_synthase_C; cd01997
1034836001781	ATP Binding subdomain [chemical binding]; other site
1034836001782	Ligand Binding sites [chemical binding]; other site
1034836001783	Dimerization subdomain; other site
1034836001784	RNA polymerase sigma-70 factor, TIGR02954 family; Region: Sig70_famx3
1034836001785	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1034836001786	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1034836001787	DNA binding residues [nucleotide binding]
1034836001788	Domain of unknown function (DUF4179); Region: DUF4179; pfam13786
1034836001789	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
1034836001790	Protein of unknown function (DUF3940); Region: DUF3940; pfam13076
1034836001791	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4843
1034836001792	Uncharacterized protein conserved in bacteria (DUF2179); Region: DUF2179; pfam10035
1034836001793	NETI protein; Region: NETI; pfam14044
1034836001794	Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase [Nucleotide transport and metabolism]; Region: PurE; COG0041
1034836001795	phosphoribosylaminoimidazole carboxylase ATPase subunit; Reviewed; Region: PRK06019
1034836001796	Formate/glycerate dehydrogenases, D-specific 2-hydroxy acid dehydrogenases and related dehydrogenases; Region: FDH_GDH_like; cl17240
1034836001797	NAD binding site [chemical binding]; other site
1034836001798	ATP-grasp domain; Region: ATP-grasp; pfam02222
1034836001799	adenylosuccinate lyase; Provisional; Region: PRK07492
1034836001800	Adenylsuccinate lyase (ASL)_subgroup 1; Region: Adenylsuccinate_lyase_1; cd01360
1034836001801	tetramer interface [polypeptide binding]; other site
1034836001802	active site
1034836001803	phosphoribosylaminoimidazole-succinocarboxamide synthase; Reviewed; Region: PRK09362
1034836001804	bacterial and archaeal 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; Region: SAICAR_synt_PurC; cd01415
1034836001805	ATP binding site [chemical binding]; other site
1034836001806	active site
1034836001807	substrate binding site [chemical binding]; other site
1034836001808	phosphoribosylformylglycinamidine synthase subunit PurS; Reviewed; Region: PRK05974
1034836001809	phosphoribosylformylglycinamidine synthase I; Provisional; Region: PRK03619
1034836001810	Type 1 glutamine amidotransferase (GATase1)-like domain found in Formylglycinamide ribonucleotide amidotransferase; Region: GATase1_FGAR_AT; cd01740
1034836001811	putative active site [active]
1034836001812	catalytic triad [active]
1034836001813	phosphoribosylformylglycinamidine synthase II; Provisional; Region: PRK01213
1034836001814	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), first repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat1; cd02203
1034836001815	dimerization interface [polypeptide binding]; other site
1034836001816	ATP binding site [chemical binding]; other site
1034836001817	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), second repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat2; cd02204
1034836001818	dimerization interface [polypeptide binding]; other site
1034836001819	ATP binding site [chemical binding]; other site
1034836001820	amidophosphoribosyltransferase; Provisional; Region: PRK07631
1034836001821	Glutamine amidotransferases class-II (GN-AT)_GPAT- type. This domain is found at the N-terminus of  glutamine phosphoribosylpyrophosphate (Prpp) amidotransferase (GPATase) . The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the...; Region: GPATase_N; cd00715
1034836001822	active site
1034836001823	tetramer interface [polypeptide binding]; other site
1034836001824	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1034836001825	active site
1034836001826	phosphoribosylaminoimidazole synthetase; Provisional; Region: PRK05385
1034836001827	PurM (Aminoimidazole Ribonucleotide [AIR] synthetase), one of eleven enzymes required for purine biosynthesis, catalyzes the conversion of formylglycinamide ribonucleotide (FGAM) and ATP to AIR, ADP, and Pi, the fifth step in de novo purine biosynthesis; Region: PurM; cd02196
1034836001828	dimerization interface [polypeptide binding]; other site
1034836001829	putative ATP binding site [chemical binding]; other site
1034836001830	phosphoribosylglycinamide formyltransferase; Reviewed; Region: purN; PRK05647
1034836001831	Phosphoribosylglycinamide formyltransferase (GAR transformylase, GART); Region: FMT_core_GART; cd08645
1034836001832	active site
1034836001833	substrate binding site [chemical binding]; other site
1034836001834	cosubstrate binding site; other site
1034836001835	catalytic site [active]
1034836001836	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional; Region: purH; PRK00881
1034836001837	Inosine monophosphate cyclohydrolase domain. This is the N-terminal domain in the purine biosynthesis pathway protein ATIC (purH). The bifunctional ATIC protein contains a C-terminal  ATIC formylase domain that formylates...; Region: IMPCH; cd01421
1034836001838	purine monophosphate binding site [chemical binding]; other site
1034836001839	dimer interface [polypeptide binding]; other site
1034836001840	putative catalytic residues [active]
1034836001841	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; smart00798
1034836001842	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; cl03362
1034836001843	phosphoribosylamine--glycine ligase; Provisional; Region: PRK00885
1034836001844	Phosphoribosylglycinamide synthetase, N domain; Region: GARS_N; pfam02844
1034836001845	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Region: GARS_A; pfam01071
1034836001846	Phosphoribosylglycinamide synthetase, C domain; Region: GARS_C; pfam02843
1034836001847	helix_turn_helix ASNC type; Region: HTH_ASNC; smart00344
1034836001848	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1034836001849	putative DNA binding site [nucleotide binding]; other site
1034836001850	putative Zn2+ binding site [ion binding]; other site
1034836001851	AsnC family; Region: AsnC_trans_reg; pfam01037
1034836001852	putative transporter; Provisional; Region: PRK11021
1034836001853	Protein of unknown function (DUF2892); Region: DUF2892; pfam11127
1034836001854	Adenine deaminase [Nucleotide transport and metabolism]; Region: AdeC; COG1001
1034836001855	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1034836001856	Adenine deaminase (AdeC) directly deaminates adenine to form hypoxanthine. This reaction is part of one of the adenine salvage pathways, as well as the degradation pathway. It is important for adenine utilization as a purine, as well as a nitrogen source...; Region: AdeC; cd01295
1034836001857	active site
1034836001858	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1034836001859	Protein of unknown function (DUF3048); Region: DUF3048; pfam11258
1034836001860	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4496
1034836001861	Glutamate synthase domain 2 [Amino acid transport and metabolism]; Region: GltB; COG0069
1034836001862	Glutamate synthase (GltS) FMN-binding domain.  GltS is a complex iron-sulfur flavoprotein that catalyzes the reductive synthesis of L-glutamate from 2-oxoglutarate and L-glutamine via intramolecular channelling of ammonia, a reaction in the plant, yeast...; Region: GltS_FMN; cd02808
1034836001863	active site
1034836001864	FMN binding site [chemical binding]; other site
1034836001865	substrate binding site [chemical binding]; other site
1034836001866	3Fe-4S cluster binding site [ion binding]; other site
1034836001867	PcrB family; Region: PcrB; pfam01884
1034836001868	PcrB_like proteins. One member of this family, a protein from Archaeoglobus fulgidus, has been characterized as a (S)-3-O-geranylgeranylglyceryl phosphate synthase (AfGGGPS). AfGGGPS catalyzes the formation of an ether linkage between...; Region: PcrB_like; cd02812
1034836001869	substrate binding site [chemical binding]; other site
1034836001870	putative active site [active]
1034836001871	dimer interface [polypeptide binding]; other site
1034836001872	ATP-dependent DNA helicase PcrA; Region: pcrA; TIGR01073
1034836001873	Part of AAA domain; Region: AAA_19; pfam13245
1034836001874	Family description; Region: UvrD_C_2; pfam13538
1034836001875	NAD-dependent DNA ligase LigA; Validated; Region: ligA; PRK07956
1034836001876	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114
1034836001877	nucleotide binding pocket [chemical binding]; other site
1034836001878	K-X-D-G motif; other site
1034836001879	catalytic site [active]
1034836001880	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
1034836001881	NAD-dependent DNA ligase C4 zinc finger domain; Region: DNA_ligase_ZBD; pfam03119
1034836001882	Helix-hairpin-helix motif; Region: HHH; pfam00633
1034836001883	Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027
1034836001884	Dimer interface [polypeptide binding]; other site
1034836001885	Protein involved in sex pheromone biosynthesis [General function prediction only]; Region: CamS; COG4851
1034836001886	N-terminal repeat domain of CamS sex pheromone cAM373 precursor; Region: CamS_repeat_1; cd13441
1034836001887	putative dimer interface [polypeptide binding]; other site
1034836001888	C-terminal repeat domain of CamS sex pheromone cAM373 precursor; Region: CamS_repeat_2; cd13440
1034836001889	putative dimer interface [polypeptide binding]; other site
1034836001890	Putative homoserine kinase type II (protein kinase fold) [General function prediction only]; Region: COG2334
1034836001891	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cl17270
1034836001892	active site
1034836001893	ATP binding site [chemical binding]; other site
1034836001894	substrate binding site [chemical binding]; other site
1034836001895	Uncharacterized membrane protein [Function unknown]; Region: SapB; COG1285
1034836001896	MgtC family; Region: MgtC; pfam02308
1034836001897	Na(+)/proline cotransporter PutP and related proteins; solute binding domain; Region: SLC5sbd_PutP; cd11475
1034836001898	Na binding site [ion binding]; other site
1034836001899	aspartyl/glutamyl-tRNA amidotransferase subunit C; Reviewed; Region: gatC; PRK00034
1034836001900	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases [Translation, ribosomal structure and biogenesis]; Region: GatA; COG0154
1034836001901	aspartyl/glutamyl-tRNA amidotransferase subunit A; Reviewed; Region: gatA; PRK00012
1034836001902	aspartyl/glutamyl-tRNA amidotransferase subunit B; Validated; Region: gatB; PRK05477
1034836001903	GatB/GatE catalytic domain; Region: GatB_N; pfam02934
1034836001904	GatB domain; Region: GatB_Yqey; pfam02637
1034836001905	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1034836001906	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1034836001907	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
1034836001908	Protein export membrane protein; Region: SecD_SecF; cl14618
1034836001909	putative lipid kinase; Reviewed; Region: PRK13337
1034836001910	Diacylglycerol kinase catalytic domain; Region: DAGK_cat; pfam00781
1034836001911	Predicted RNA-binding protein, contains TRAM domain [General function prediction only]; Region: COG3269
1034836001912	23S rRNA (uracil-5-)-methyltransferase RumA; Region: rumA; TIGR00479
1034836001913	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1034836001914	S-adenosylmethionine binding site [chemical binding]; other site
1034836001915	Part of AAA domain; Region: AAA_19; pfam13245
1034836001916	Uncharacterized conserved protein (DUF2075); Region: DUF2075; pfam09848
1034836001917	Uncharacterized conserved protein [Function unknown]; Region: COG3410
1034836001918	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
1034836001919	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1034836001920	Walker A/P-loop; other site
1034836001921	ATP binding site [chemical binding]; other site
1034836001922	Q-loop/lid; other site
1034836001923	ABC transporter signature motif; other site
1034836001924	Walker B; other site
1034836001925	D-loop; other site
1034836001926	H-loop/switch region; other site
1034836001927	Domain of unknown function (DUF4162); Region: DUF4162; pfam13732
1034836001928	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
1034836001929	Protein of unknown function, DUF600; Region: DUF600; cl04640
1034836001930	Protein of unknown function, DUF600; Region: DUF600; cl04640
1034836001931	Protein of unknown function, DUF600; Region: DUF600; pfam04634
1034836001932	DNA/RNA non-specific endonuclease; Region: Endonuclea_NS_2; pfam13930
1034836001933	LXG domain of WXG superfamily; Region: LXG; pfam04740
1034836001934	hypothetical protein; Provisional; Region: PRK12378
1034836001935	Streptomycin adenylyltransferase; Region: Adenyl_transf; pfam04439
1034836001936	Spore coat associated protein JA (CotJA); Region: CotJA; pfam11007
1034836001937	CotJB protein; Region: CotJB; pfam12652
1034836001938	Manganese catalase, ferritin-like diiron-binding domain; Region: Mn_catalase; cd01051
1034836001939	dimanganese center [ion binding]; other site
1034836001940	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1034836001941	Coenzyme A binding pocket [chemical binding]; other site
1034836001942	YesK-like protein; Region: YesK; pfam14150
1034836001943	Predicted membrane protein [Function unknown]; Region: COG2323
1034836001944	Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides [General function prediction only]; Region: COG2329
1034836001945	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1034836001946	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_16; cd07263
1034836001947	Sulphate Transporter and Anti-Sigma factor antagonist domain of the "stressosome" complex proteins RsbS and RsbR, regulators of the bacterial stress activated alternative sigma factor sigma-B by phosphorylation; Region: STAS_RsbR_RsbS_like; cd07041
1034836001948	Uncharacterized small protein [Function unknown]; Region: COG5583
1034836001949	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
1034836001950	Bacterial BAX inhibitor (BI)-1/YccA-like proteins; Region: BI-1-like_bacterial; cd10432
1034836001951	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1034836001952	MarR family; Region: MarR; pfam01047
1034836001953	hypothetical protein; Provisional; Region: PRK06847
1034836001954	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
1034836001955	Protein of unknown function (DUF3900); Region: DUF3900; pfam13039
1034836001956	Domain of unknown function (DUF3898); Region: DUF3898; pfam13037
1034836001957	Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]; Region: CypX; COG2124
1034836001958	Cytochrome P450; Region: p450; pfam00067
1034836001959	Sulfite reductase, alpha subunit (flavoprotein) [Inorganic ion transport and metabolism]; Region: CysJ; COG0369
1034836001960	Flavodoxin; Region: Flavodoxin_1; pfam00258
1034836001961	These bifunctional proteins fuse N-terminal cytochrome p450 with a cytochrome p450 reductase (CYPOR). NADPH cytochrome p450 reductase serves as an electron donor in several oxygenase systems and is a component of nitric oxide synthases and methionine...; Region: bifunctional_CYPOR; cd06206
1034836001962	FAD binding pocket [chemical binding]; other site
1034836001963	FAD binding motif [chemical binding]; other site
1034836001964	catalytic residues [active]
1034836001965	NAD binding pocket [chemical binding]; other site
1034836001966	phosphate binding motif [ion binding]; other site
1034836001967	beta-alpha-beta structure motif; other site
1034836001968	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily [Cell envelope biogenesis, outer membrane]; Region: MdoB; COG1368
1034836001969	Sulfatase; Region: Sulfatase; pfam00884
1034836001970	Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) [Cell envelope biogenesis, outer membrane / Translation, ribosomal structure...; Region: GCD1; COG1208
1034836001971	G1P_cytidylyltransferase catalyzes the production of CDP-D-Glucose; Region: G1P_cytidylyltransferase; cd02524
1034836001972	substrate binding site; other site
1034836001973	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
1034836001974	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1034836001975	NAD(P) binding site [chemical binding]; other site
1034836001976	active site
1034836001977	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1034836001978	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
1034836001979	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
1034836001980	active site
1034836001981	N-terminal domain of galactosyltransferase; Region: Glyco_transf_7C; cl17476
1034836001982	Nucleotide-diphospho-sugar transferase; Region: Nucleotid_trans; pfam03407
1034836001983	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1034836001984	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1034836001985	putative substrate translocation pore; other site
1034836001986	amino acid transporter; Region: 2A0306; TIGR00909
1034836001987	C-terminus of AA_permease; Region: AA_permease_C; pfam13906
1034836001988	NADP+-dependent p-hydroxybenzaldehyde dehydrogenase-like; Region: ALDH_HBenzADH; cd07151
1034836001989	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
1034836001990	NAD(P) binding site [chemical binding]; other site
1034836001991	catalytic residues [active]
1034836001992	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1034836001993	dimer interface [polypeptide binding]; other site
1034836001994	putative CheW interface [polypeptide binding]; other site
1034836001995	oxidoreductase; Provisional; Region: PRK07985
1034836001996	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1034836001997	NAD(P) binding site [chemical binding]; other site
1034836001998	active site
1034836001999	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
1034836002000	UDP-glucose LOS-beta-1,4 glucosyltransferase is required for biosynthesis of lipooligosaccharide; Region: Beta4Glucosyltransferase; cd02511
1034836002001	putative metal binding site; other site
1034836002002	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
1034836002003	binding surface
1034836002004	TPR motif; other site
1034836002005	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
1034836002006	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1034836002007	Walker A/P-loop; other site
1034836002008	ATP binding site [chemical binding]; other site
1034836002009	Q-loop/lid; other site
1034836002010	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1034836002011	ABC transporter signature motif; other site
1034836002012	Walker B; other site
1034836002013	D-loop; other site
1034836002014	ABC transporter; Region: ABC_tran_2; pfam12848
1034836002015	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1034836002016	Predicted transcriptional regulators [Transcription]; Region: SoxR; COG0789
1034836002017	Helix-Turn-Helix DNA binding domain of transcription regulators from the MerR superfamily; Region: HTH_MerR-SF; cl02600
1034836002018	DNA binding residues [nucleotide binding]
1034836002019	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
1034836002020	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1034836002021	putative substrate translocation pore; other site
1034836002022	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
1034836002023	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1034836002024	Walker A/P-loop; other site
1034836002025	ATP binding site [chemical binding]; other site
1034836002026	Q-loop/lid; other site
1034836002027	ABC transporter signature motif; other site
1034836002028	Walker B; other site
1034836002029	D-loop; other site
1034836002030	H-loop/switch region; other site
1034836002031	ABC transporter; Region: ABC_tran_2; pfam12848
1034836002032	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1034836002033	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
1034836002034	DEAD-like helicases superfamily; Region: DEXDc; smart00487
1034836002035	ATP binding site [chemical binding]; other site
1034836002036	Mg++ binding site [ion binding]; other site
1034836002037	motif III; other site
1034836002038	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1034836002039	nucleotide binding region [chemical binding]; other site
1034836002040	ATP-binding site [chemical binding]; other site
1034836002041	Putative NADP-dependent oxidoreductases [General function prediction only]; Region: COG2130
1034836002042	Prostaglandin dehydrogenases; Region: PGDH; cd05288
1034836002043	NAD(P) binding site [chemical binding]; other site
1034836002044	substrate binding site [chemical binding]; other site
1034836002045	dimer interface [polypeptide binding]; other site
1034836002046	Protein of unknown function (DUF3212); Region: DUF3212; pfam11486
1034836002047	Heat induced stress protein YflT; Region: YflT; pfam11181
1034836002048	Pectate lyase [Carbohydrate transport and metabolism]; Region: PelB; COG3866
1034836002049	Amb_all domain; Region: Amb_all; smart00656
1034836002050	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
1034836002051	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cd00625
1034836002052	transmembrane helices; other site
1034836002053	BclB C-terminal domain; Region: exospore_TM; TIGR03721
1034836002054	7TM diverse intracellular signalling; Region: 7TMR-DISM_7TM; pfam07695
1034836002055	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1034836002056	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1034836002057	dimer interface [polypeptide binding]; other site
1034836002058	phosphorylation site [posttranslational modification]
1034836002059	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1034836002060	ATP binding site [chemical binding]; other site
1034836002061	Mg2+ binding site [ion binding]; other site
1034836002062	G-X-G motif; other site
1034836002063	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
1034836002064	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1034836002065	active site
1034836002066	phosphorylation site [posttranslational modification]
1034836002067	intermolecular recognition site; other site
1034836002068	dimerization interface [polypeptide binding]; other site
1034836002069	Predicted signal transduction protein with a C-terminal ATPase domain [Signal transduction mechanisms]; Region: COG2972
1034836002070	Histidine kinase; Region: His_kinase; pfam06580
1034836002071	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1034836002072	ATP binding site [chemical binding]; other site
1034836002073	Mg2+ binding site [ion binding]; other site
1034836002074	G-X-G motif; other site
1034836002075	Response regulator containing CheY-like receiver and SARP domains [Signal transduction mechanisms]; Region: COG3947
1034836002076	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1034836002077	active site
1034836002078	phosphorylation site [posttranslational modification]
1034836002079	intermolecular recognition site; other site
1034836002080	dimerization interface [polypeptide binding]; other site
1034836002081	Transcriptional regulatory protein, C terminal; Region: Trans_reg_C; smart00862
1034836002082	Predicted outer membrane protein [Cell envelope biogenesis, outer membrane]; Region: COG4932
1034836002083	Collagen binding domain; Region: Collagen_bind; pfam05737
1034836002084	Collagen binding domain; Region: Collagen_bind; pfam05737
1034836002085	Collagen binding domain; Region: Collagen_bind; pfam05737
1034836002086	Collagen binding domain; Region: Collagen_bind; pfam05737
1034836002087	Cna protein B-type domain; Region: Cna_B; pfam05738
1034836002088	Cna protein B-type domain; Region: Cna_B; pfam05738
1034836002089	Cna protein B-type domain; Region: Cna_B; pfam05738
1034836002090	Predicted outer membrane protein [Cell envelope biogenesis, outer membrane]; Region: COG4932
1034836002091	Cna protein B-type domain; Region: Cna_B; pfam05738
1034836002092	Cna protein B-type domain; Region: Cna_B; pfam05738
1034836002093	Cna protein B-type domain; Region: Cna_B; pfam05738
1034836002094	Cna protein B-type domain; Region: Cna_B; pfam05738
1034836002095	Cna protein B-type domain; Region: Cna_B; pfam05738
1034836002096	Cna protein B-type domain; Region: Cna_B; pfam05738
1034836002097	Sortase A (SrtA) or subfamily-1 sortases are cysteine transpeptidases found in gram-positive bacteria that anchor surface proteins to peptidoglycans of the bacterial cell wall envelope. They do so by catalyzing a transpeptidation reaction in which the...; Region: Sortase_A_1; cd06165
1034836002098	active site
1034836002099	catalytic site [active]
1034836002100	Signal transduction histidine kinase regulating citrate/malate metabolism [Signal transduction mechanisms]; Region: CitA; COG3290
1034836002101	PAS domain; Region: PAS; smart00091
1034836002102	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1034836002103	ATP binding site [chemical binding]; other site
1034836002104	Mg2+ binding site [ion binding]; other site
1034836002105	G-X-G motif; other site
1034836002106	Response regulator of citrate/malate metabolism [Transcription / Signal transduction mechanisms]; Region: CitB; COG4565
1034836002107	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1034836002108	active site
1034836002109	phosphorylation site [posttranslational modification]
1034836002110	intermolecular recognition site; other site
1034836002111	dimerization interface [polypeptide binding]; other site
1034836002112	Transcriptional regulator; Region: CitT; pfam12431
1034836002113	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3181
1034836002114	H+/citrate symporter [Energy production and conversion]; Region: CitM; cl17620
1034836002115	Citrate transporter; Region: CitMHS; pfam03600
1034836002116	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
1034836002117	Nitric oxide synthase (NOS) prokaryotic oxygenase domain. NOS produces nitric oxide (NO) by catalyzing a five-electron heme-based oxidation of a guanidine nitrogen of L-arginine to L-citrulline via two successive monooxygenation reactions producing N...; Region: NOS_oxygenase_prok; cd00794
1034836002118	active site
1034836002119	dimer interface [polypeptide binding]; other site
1034836002120	Acylphosphatase; Region: Acylphosphatase; cl00551
1034836002121	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2258
1034836002122	MOSC domain; Region: MOSC; pfam03473
1034836002123	3-alpha domain; Region: 3-alpha; pfam03475
1034836002124	Protein of unknown function (DUF2639); Region: DUF2639; pfam11121
1034836002125	Protein of unknown function (DUF3243); Region: DUF3243; pfam11588
1034836002126	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
1034836002127	active site
1034836002128	PTS system, N-acetylglucosamine-specific IIBC component; Region: PTS-II-BC-nag; TIGR01998
1034836002129	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1034836002130	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1034836002131	active site turn [active]
1034836002132	phosphorylation site [posttranslational modification]
1034836002133	Uncharacterized protein from bacillus cereus group; Region: YfmQ; pfam10787
1034836002134	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily [Cell envelope biogenesis, outer membrane]; Region: MdoB; COG1368
1034836002135	Sulfatase; Region: Sulfatase; pfam00884
1034836002136	Domain of unknown function (DUF1992); Region: DUF1992; pfam09350
1034836002137	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
1034836002138	Alpha-crystallin domain (ACD) of alpha-crystallin-type small(s) heat shock proteins (Hsps). sHsps are small stress induced proteins with monomeric masses between 12 -43 kDa, whose common feature is the Alpha-crystallin domain  (ACD). sHsps are generally...; Region: ACD_sHsps-like; cd06464
1034836002139	putative dimer interface [polypeptide binding]; other site
1034836002140	Spore germination protein gerPA/gerPF; Region: gerPA; pfam10676
1034836002141	Spore germination protein gerPA/gerPF; Region: gerPA; pfam10676
1034836002142	PTS system, trehalose-specific IIBC component; Region: PTS-IIBC-Tre; TIGR01992
1034836002143	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1034836002144	active site turn [active]
1034836002145	phosphorylation site [posttranslational modification]
1034836002146	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1034836002147	alpha,alpha-phosphotrehalase; Region: trehalose_treC; TIGR02403
1034836002148	Alpha amylase catalytic domain found in Sucrose isomerases, oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase), dextran glucosidase (also called glucan 1,6-alpha-glucosidase), and related proteins; Region: AmyAc_SI_OligoGlu_DGase; cd11333
1034836002149	Ca binding site [ion binding]; other site
1034836002150	active site
1034836002151	catalytic site [active]
1034836002152	trehalose operon repressor, B. subtilis-type; Region: trehalos_R_Bsub; TIGR02404
1034836002153	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1034836002154	DNA-binding site [nucleotide binding]; DNA binding site
1034836002155	UTRA domain; Region: UTRA; pfam07702
1034836002156	NAD(P)H:FMN oxidoreductase family. This domain catalyzes the reduction of flavin, nitrocompound, quinones and azo compounds using NADH or NADPH as an electron donor. The enzyme is a homodimer, and each monomer binds a FMN as co-factor. This family...; Region: NfsB_like_nitroreductase; cd02149
1034836002157	dimer interface [polypeptide binding]; other site
1034836002158	FMN binding site [chemical binding]; other site
1034836002159	YibE/F-like protein; Region: YibE_F; pfam07907
1034836002160	YibE/F-like protein; Region: YibE_F; pfam07907
1034836002161	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase precursor protein; Reviewed; Region: PRK09419
1034836002162	Escherichia coli CpdB and related proteins, N-terminal metallophosphatase domain; Region: MPP_CpdB_N; cd07410
1034836002163	active site
1034836002164	metal binding site [ion binding]; metal-binding site
1034836002165	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
1034836002166	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
1034836002167	active site
1034836002168	metal binding site [ion binding]; metal-binding site
1034836002169	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
1034836002170	intracellular protease, PfpI family; Region: PfpI; TIGR01382
1034836002171	A type 1 glutamine amidotransferase (GATase1)-like domain found in PfpI from Pyrococcus furiosus; Region: GATase1_PfpI_like; cd03134
1034836002172	proposed catalytic triad [active]
1034836002173	conserved cys residue [active]
1034836002174	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1034836002175	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1034836002176	DNA binding site [nucleotide binding]
1034836002177	domain linker motif; other site
1034836002178	Ligand-binding domain of MalI, a transcription regulator of the maltose system of Escherichia coli and its close homologs from other bacteria; Region: PBP1_MalI_like; cd06289
1034836002179	putative dimerization interface [polypeptide binding]; other site
1034836002180	putative ligand binding site [chemical binding]; other site
1034836002181	shikimate 5-dehydrogenase; Provisional; Region: PRK12548
1034836002182	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
1034836002183	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
1034836002184	shikimate binding site; other site
1034836002185	NAD(P) binding site [chemical binding]; other site
1034836002186	3-dehydroquinate dehydratase [Amino acid transport and metabolism]; Region: AroD; COG0710
1034836002187	Type I 3-dehydroquinase, (3-dehydroquinate dehydratase or DHQase); Region: DHQase_I; cd00502
1034836002188	active site
1034836002189	catalytic residue [active]
1034836002190	dimer interface [polypeptide binding]; other site
1034836002191	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1034836002192	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1034836002193	putative substrate translocation pore; other site
1034836002194	Protein of unknown function (DUF1128); Region: DUF1128; pfam06569
1034836002195	Protein-tyrosine-phosphatase [Signal transduction mechanisms]; Region: Wzb; COG0394
1034836002196	Low molecular weight phosphatase family; Region: LMWPc; cd00115
1034836002197	active site
1034836002198	Virulence factor BrkB; Region: Virul_fac_BrkB; cl07918
1034836002199	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1034836002200	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1034836002201	putative substrate translocation pore; other site
1034836002202	calcium/proton exchanger (cax); Region: cax; TIGR00378
1034836002203	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
1034836002204	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
1034836002205	YfkD-like protein; Region: YfkD; pfam14167
1034836002206	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
1034836002207	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1034836002208	Radical SAM superfamily; Region: Radical_SAM; pfam04055
1034836002209	YfkB-like domain; Region: YfkB; pfam08756
1034836002210	Catalytic NodB homology domain of Bacillus subtilis polysaccharide deacetylase PdaA, and its bacterial homologs; Region: CE4_BsPdaA_like; cd10948
1034836002211	delta-lactam-biosynthetic de-N-acetylase; Region: spore_pdaA; TIGR02884
1034836002212	NodB motif; other site
1034836002213	active site
1034836002214	catalytic site [active]
1034836002215	Cd binding site [ion binding]; other site
1034836002216	3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases [Lipid metabolism]; Region: MmsB; COG2084
1034836002217	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
1034836002218	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
1034836002219	Uncharacterized bacterial subfamily of the Thermotoga maritima CorA-like family; Region: TmCorA-like_u2; cd12831
1034836002220	oligomer interface [polypeptide binding]; other site
1034836002221	metal binding site [ion binding]; metal-binding site
1034836002222	metal binding site [ion binding]; metal-binding site
1034836002223	putative Cl binding site [ion binding]; other site
1034836002224	aspartate ring; other site
1034836002225	basic sphincter; other site
1034836002226	hydrophobic gate; other site
1034836002227	periplasmic entrance; other site
1034836002228	The Ntn hydrolases (N-terminal nucleophile) are a diverse superfamily of of enzymes that are activated autocatalytically via an N-terminally lcated nucleophilic amino acid.  N-terminal nucleophile (NTN-) hydrolase superfamily, which contains a...; Region: Ntn_hydrolase; cl00467
1034836002229	3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase [DNA replication, recombination, and repair]; Region: AlkA; COG0122
1034836002230	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
1034836002231	minor groove reading motif; other site
1034836002232	helix-hairpin-helix signature motif; other site
1034836002233	substrate binding pocket [chemical binding]; other site
1034836002234	active site
1034836002235	TRAM domain; Region: TRAM; pfam01938
1034836002236	23S rRNA (uracil-5-)-methyltransferase RumA; Region: rumA; TIGR00479
1034836002237	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1034836002238	S-adenosylmethionine binding site [chemical binding]; other site
1034836002239	Peptidase domain in the S8 and S53 families; Region: Peptidases_S8_S53; cl10459
1034836002240	active site
1034836002241	catalytic residues [active]
1034836002242	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1034836002243	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1034836002244	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1034836002245	Walker A/P-loop; other site
1034836002246	ATP binding site [chemical binding]; other site
1034836002247	Q-loop/lid; other site
1034836002248	ABC transporter signature motif; other site
1034836002249	Walker B; other site
1034836002250	D-loop; other site
1034836002251	H-loop/switch region; other site
1034836002252	Protein Kinases, catalytic domain; Region: PKc_like; cl09925
1034836002253	active site
1034836002254	ATP binding site [chemical binding]; other site
1034836002255	substrate binding site [chemical binding]; other site
1034836002256	activation loop (A-loop); other site
1034836002257	Lanthionine synthetase C-like protein; Region: LANC_like; pfam05147
1034836002258	LanC-like proteins. LanC is the cyclase enzyme of the lanthionine synthetase. Lanthionine is a lantibiotic, a unique class of peptide antibiotics. They are ribosomally synthesized as a precursor peptide and then post-translationally modified to contain...; Region: LanC_like; cl04955
1034836002259	active site
1034836002260	zinc binding site [ion binding]; other site
1034836002261	Subunit B of Class III Extradiol ring-cleavage dioxygenases; Region: Extradiol_Dioxygenase_3B_like; cl00599
1034836002262	tRNA-dihydrouridine synthase [Translation, ribosomal structure and biogenesis]; Region: COG0042
1034836002263	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
1034836002264	FMN binding site [chemical binding]; other site
1034836002265	active site
1034836002266	catalytic residues [active]
1034836002267	substrate binding site [chemical binding]; other site
1034836002268	Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit [Energy production and conversion]; Region: AcoA; COG1071
1034836002269	Thiamine pyrophosphate (TPP) family, E1 of PDC_ADC_BCADC subfamily, TPP-binding module; composed of proteins similar to the E1 components of the human pyruvate dehydrogenase complex (PDC), the acetoin dehydrogenase complex (ADC) and the branched chain...; Region: TPP_E1_PDC_ADC_BCADC; cd02000
1034836002270	tetramer interface [polypeptide binding]; other site
1034836002271	TPP-binding site [chemical binding]; other site
1034836002272	heterodimer interface [polypeptide binding]; other site
1034836002273	phosphorylation loop region [posttranslational modification]
1034836002274	Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit [Energy production and conversion]; Region: AcoB; COG0022
1034836002275	Pyrimidine (PYR) binding domain of the beta subunits of the E1 components of human pyruvate dehydrogenase complex (E1- PDHc) and related proteins; Region: TPP_PYR_E1-PDHc-beta_like; cd07036
1034836002276	alpha subunit interface [polypeptide binding]; other site
1034836002277	TPP binding site [chemical binding]; other site
1034836002278	heterodimer interface [polypeptide binding]; other site
1034836002279	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1034836002280	branched-chain alpha-keto acid dehydrogenase subunit E2; Reviewed; Region: PRK11856
1034836002281	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1034836002282	E3 interaction surface; other site
1034836002283	lipoyl attachment site [posttranslational modification]; other site
1034836002284	e3 binding domain; Region: E3_binding; pfam02817
1034836002285	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
1034836002286	dihydrolipoamide dehydrogenase; Validated; Region: acoL; PRK06912
1034836002287	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1034836002288	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
1034836002289	Transcriptional activator of acetoin/glycerol metabolism [Secondary metabolites biosynthesis, transport, and catabolism / Transcription]; Region: AcoR; COG3284
1034836002290	GAF domain; Region: GAF; pfam01590
1034836002291	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1034836002292	Walker A motif; other site
1034836002293	ATP binding site [chemical binding]; other site
1034836002294	Walker B motif; other site
1034836002295	arginine finger; other site
1034836002296	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
1034836002297	Small acid-soluble spore protein H family; Region: SspH; pfam08141
1034836002298	Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: CelF; COG1486
1034836002299	Glycoside Hydrolases Family 4; GlvA- and pagL-like glycosidases; Region: GH4_GlvA_pagL_like; cd05298
1034836002300	NAD binding site [chemical binding]; other site
1034836002301	sugar binding site [chemical binding]; other site
1034836002302	divalent metal binding site [ion binding]; other site
1034836002303	putative tetramer (dimer of dimers) interface [polypeptide binding]; other site
1034836002304	dimer interface [polypeptide binding]; other site
1034836002305	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
1034836002306	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
1034836002307	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
1034836002308	putative active site [active]
1034836002309	PTS system, alpha-glucoside-specific IIBC component; Region: PTS-IIBC-alpha; TIGR02005
1034836002310	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1034836002311	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1034836002312	active site turn [active]
1034836002313	phosphorylation site [posttranslational modification]
1034836002314	Pectate lyase superfamily protein; Region: Pectate_lyase_3; pfam12708
1034836002315	Peptidase_G2, IMC autoproteolytic cleavage domain; Region: Peptidase_G2; pfam11962
1034836002316	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1034836002317	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1034836002318	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1034836002319	Walker A/P-loop; other site
1034836002320	ATP binding site [chemical binding]; other site
1034836002321	Q-loop/lid; other site
1034836002322	ABC transporter signature motif; other site
1034836002323	Walker B; other site
1034836002324	D-loop; other site
1034836002325	H-loop/switch region; other site
1034836002326	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1034836002327	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1034836002328	ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Region: ABCC_Glucan_exporter_like; cd03254
1034836002329	Walker A/P-loop; other site
1034836002330	ATP binding site [chemical binding]; other site
1034836002331	Q-loop/lid; other site
1034836002332	ABC transporter signature motif; other site
1034836002333	Walker B; other site
1034836002334	D-loop; other site
1034836002335	H-loop/switch region; other site
1034836002336	Predicted membrane protein [Function unknown]; Region: COG2259
1034836002337	Predicted ring-cleavage extradiol dioxygenase [General function prediction only]; Region: COG2514
1034836002338	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_12; cd07255
1034836002339	putative metal binding site [ion binding]; other site
1034836002340	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cl14632
1034836002341	active site
1034836002342	potential frameshift: common BLAST hit: gi|154685298|ref|YP_001420459.1| CtaO
1034836002343	Predicted transcriptional regulators [Transcription]; Region: COG1695
1034836002344	Transcriptional regulator PadR-like family; Region: PadR; pfam03551
1034836002345	Virulence activator alpha C-term; Region: Vir_act_alpha_C; pfam10400
1034836002346	Flavodoxin-like fold; Region: Flavodoxin_2; pfam02525
1034836002347	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
1034836002348	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis/biofilm formation [Carbohydrate transport and metabolism]; Region: COG3936
1034836002349	Acyltransferase family; Region: Acyl_transf_3; pfam01757
1034836002350	Barstar is an intracellular inhibitor of barnase, an extracellular ribonuclease of Bacillus amyloliquefaciens. Barstar binds tightly to the barnase active site and sterically blocks it thus inhibiting its potentially lethal RNase activity inside the cell; Region: Barstar; cd05142
1034836002351	RNAase interaction site [polypeptide binding]; other site
1034836002352	metal-dependent hydrolase; Provisional; Region: PRK13291
1034836002353	DinB superfamily; Region: DinB_2; pfam12867
1034836002354	benzoate transport; Region: 2A0115; TIGR00895
1034836002355	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1034836002356	putative substrate translocation pore; other site
1034836002357	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1034836002358	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1034836002359	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1034836002360	putative Zn2+ binding site [ion binding]; other site
1034836002361	putative DNA binding site [nucleotide binding]; other site
1034836002362	Predicted integral membrane protein [Function unknown]; Region: COG0392
1034836002363	Uncharacterized conserved protein [Function unknown]; Region: COG2898
1034836002364	Uncharacterized conserved protein (DUF2156); Region: DUF2156; pfam09924
1034836002365	phenazine biosynthesis protein PhzF family; Region: PhzF_family; TIGR00654
1034836002366	Nitroreductase-like family which includes NADH oxidase and arsenite oxidiase. NADH oxidase catalyses the oxidation of NAD(P)H and accepts a wide broad range of compounds as electron acceptors, such as nitrocompound. Arsenite oxidase in a...; Region: Arsenite_oxidase; cd02135
1034836002367	putative FMN binding site [chemical binding]; other site
1034836002368	YfhD-like protein; Region: YfhD; pfam14151
1034836002369	YfhE-like protein; Region: YfhE; pfam14152
1034836002370	atypical (a) SDRs, subgroup 8; Region: SDR_a8; cd05242
1034836002371	TIGR01777 family protein; Region: yfcH
1034836002372	putative NAD(P) binding site [chemical binding]; other site
1034836002373	putative active site [active]
1034836002374	recombination regulator RecX; Provisional; Region: recX; PRK14135
1034836002375	Protein of unknown function (DUF1811); Region: DUF1811; pfam08838
1034836002376	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
1034836002377	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1034836002378	putative substrate translocation pore; other site
1034836002379	Protein of unknown function (DUF2606); Region: DUF2606; pfam10794
1034836002380	V8-like Glu-specific endopeptidase [Amino acid transport and metabolism]; Region: COG3591
1034836002381	acid-soluble spore protein K; Provisional; Region: sspK; PRK03081
1034836002382	WVELL protein; Region: WVELL; pfam14043
1034836002383	Bacterial SH3 domain; Region: SH3_3; pfam08239
1034836002384	Bacterial SH3 domain; Region: SH3_3; cl17532
1034836002385	SdpI/YhfL protein family; Region: SdpI; pfam13630
1034836002386	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
1034836002387	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
1034836002388	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
1034836002389	Ligand binding site; other site
1034836002390	Putative Catalytic site; other site
1034836002391	DXD motif; other site
1034836002392	Predicted membrane protein [Function unknown]; Region: COG4485
1034836002393	Caenorhabditis protein of unknown function, DUF267; Region: DUF267; pfam03268
1034836002394	Predicted membrane-bound metal-dependent hydrolases [General function prediction only]; Region: COG1988
1034836002395	A/G-specific DNA glycosylase [DNA replication, recombination, and repair]; Region: MutY; COG1194
1034836002396	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
1034836002397	minor groove reading motif; other site
1034836002398	helix-hairpin-helix signature motif; other site
1034836002399	substrate binding pocket [chemical binding]; other site
1034836002400	active site
1034836002401	Iron-sulfur binding domain of endonuclease III; Region: EndIII_4Fe-2S; pfam10576
1034836002402	DNA glycosylase (MutY in bacteria and hMYH in humans) is responsible for repairing misread  A*oxoG residues to C*G by removing the inappropriately paired adenine base from the DNA backbone. It belongs to the Nudix hydrolase superfamily and is important...; Region: DNA_Glycosylase_C; cd03431
1034836002403	DNA binding and oxoG recognition site [nucleotide binding]
1034836002404	enoyl-(acyl carrier protein) reductase; Provisional; Region: PRK08063
1034836002405	1-cyclohexenylcarbonyl_coenzyme A_reductase (ChcA)_like, classical (c) SDRs; Region: ChcA_like_SDR_c; cd05359
1034836002406	putative NAD(P) binding site [chemical binding]; other site
1034836002407	active site
1034836002408	YgaB-like protein; Region: YgaB; pfam14182
1034836002409	hypothetical protein; Provisional; Region: PRK13662
1034836002410	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1034836002411	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1034836002412	ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; Region: ABCC_MsbA; cd03251
1034836002413	Walker A/P-loop; other site
1034836002414	ATP binding site [chemical binding]; other site
1034836002415	Q-loop/lid; other site
1034836002416	ABC transporter signature motif; other site
1034836002417	Walker B; other site
1034836002418	D-loop; other site
1034836002419	H-loop/switch region; other site
1034836002420	Predicted membrane protein [Function unknown]; Region: COG4129
1034836002421	Bacterial protein of unknown function (DUF939); Region: DUF939; pfam06081
1034836002422	glutamate-1-semialdehyde aminotransferase; Provisional; Region: PRK12389
1034836002423	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1034836002424	inhibitor-cofactor binding pocket; inhibition site
1034836002425	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1034836002426	catalytic residue [active]
1034836002427	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
1034836002428	Peroxiredoxin (PRX) family, Bacterioferritin comigratory protein (BCP) subfamily; composed of thioredoxin-dependent thiol peroxidases, widely expressed in pathogenic bacteria, that protect cells against toxicity from reactive oxygen species by reducing...; Region: PRX_BCP; cd03017
1034836002429	catalytic triad [active]
1034836002430	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
1034836002431	metal binding site 2 [ion binding]; metal-binding site
1034836002432	putative DNA binding helix; other site
1034836002433	metal binding site 1 [ion binding]; metal-binding site
1034836002434	dimer interface [polypeptide binding]; other site
1034836002435	structural Zn2+ binding site [ion binding]; other site
1034836002436	Protein of unknown function (DUF2614); Region: DUF2614; pfam11023
1034836002437	Na+/H+ antiporter family; Region: Na_H_antiporter; pfam03553
1034836002438	Type 1 glutamine amidotransferase (GATase1)-like domain found in peptidase E; Region: GAT1_Peptidase_E; cd03146
1034836002439	active site pocket [active]
1034836002440	oxyanion hole [active]
1034836002441	catalytic triad [active]
1034836002442	active site nucleophile [active]
1034836002443	thiamine biosynthesis protein ThiC; Provisional; Region: PRK09284
1034836002444	ThiC-associated domain; Region: ThiC-associated; pfam13667
1034836002445	Thiamine biosynthesis protein ThiC [Coenzyme metabolism]; Region: ThiC; COG0422
1034836002446	FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277
1034836002447	FAD binding domain; Region: FAD_binding_4; pfam01565
1034836002448	Berberine and berberine like; Region: BBE; pfam08031
1034836002449	Protein of unknown function (DUF3901); Region: DUF3901; pfam13040
1034836002450	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
1034836002451	The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cl01709
1034836002452	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
1034836002453	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1034836002454	dimer interface [polypeptide binding]; other site
1034836002455	conserved gate region; other site
1034836002456	putative PBP binding loops; other site
1034836002457	ABC-ATPase subunit interface; other site
1034836002458	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
1034836002459	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
1034836002460	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1034836002461	dimer interface [polypeptide binding]; other site
1034836002462	conserved gate region; other site
1034836002463	putative PBP binding loops; other site
1034836002464	ABC-ATPase subunit interface; other site
1034836002465	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppD; COG0444
1034836002466	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1034836002467	Walker A/P-loop; other site
1034836002468	ATP binding site [chemical binding]; other site
1034836002469	Q-loop/lid; other site
1034836002470	ABC transporter signature motif; other site
1034836002471	Walker B; other site
1034836002472	D-loop; other site
1034836002473	H-loop/switch region; other site
1034836002474	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
1034836002475	ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism]; Region: AppF; COG4608
1034836002476	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1034836002477	Walker A/P-loop; other site
1034836002478	ATP binding site [chemical binding]; other site
1034836002479	Q-loop/lid; other site
1034836002480	ABC transporter signature motif; other site
1034836002481	Walker B; other site
1034836002482	D-loop; other site
1034836002483	H-loop/switch region; other site
1034836002484	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
1034836002485	Catalase [Inorganic ion transport and metabolism]; Region: KatE; COG0753
1034836002486	Clade 3 of the heme-binding enzyme catalase; Region: catalase_clade_3; cd08156
1034836002487	tetramer interface [polypeptide binding]; other site
1034836002488	heme binding pocket [chemical binding]; other site
1034836002489	NADPH binding site [chemical binding]; other site
1034836002490	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cd01292
1034836002491	active site
1034836002492	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: TauB; COG1116
1034836002493	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
1034836002494	Walker A/P-loop; other site
1034836002495	ATP binding site [chemical binding]; other site
1034836002496	Q-loop/lid; other site
1034836002497	ABC transporter signature motif; other site
1034836002498	Walker B; other site
1034836002499	D-loop; other site
1034836002500	H-loop/switch region; other site
1034836002501	ABC transporter, substrate-binding protein, aliphatic sulfonates family; Region: SsuA_fam; TIGR01728
1034836002502	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1034836002503	substrate binding pocket [chemical binding]; other site
1034836002504	membrane-bound complex binding site; other site
1034836002505	hinge residues; other site
1034836002506	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
1034836002507	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1034836002508	dimer interface [polypeptide binding]; other site
1034836002509	conserved gate region; other site
1034836002510	putative PBP binding loops; other site
1034836002511	ABC-ATPase subunit interface; other site
1034836002512	alkanesulfonate monooxygenase; Provisional; Region: PRK00719
1034836002513	Alkanesulfonate monoxygenase is the monoxygenase of a two-component system that catalyzes the conversion of alkanesulfonates to the corresponding aldehyde and sulfite. Alkanesulfonate monoxygenase (SsuD) has an absolute requirement for reduced flavin...; Region: Alkanesulfonate_monoxygenase; cd01094
1034836002514	active site
1034836002515	dimer interface [polypeptide binding]; other site
1034836002516	non-prolyl cis peptide bond; other site
1034836002517	insertion regions; other site
1034836002518	potential frameshift: common BLAST hit: gi|308172874|ref|YP_003919579.1| sulfur oxidoreductase
1034836002519	30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08881
1034836002520	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1034836002521	non-specific DNA binding site [nucleotide binding]; other site
1034836002522	salt bridge; other site
1034836002523	sequence-specific DNA binding site [nucleotide binding]; other site
1034836002524	Solo B3/4 domain (OB-fold DNA/RNA-binding) of Phe-aaRS-beta [General function prediction only]; Region: COG3382
1034836002525	epoxyqueuosine reductase; Region: TIGR00276
1034836002526	Domain of unknown function (DUF1730); Region: DUF1730; pfam08331
1034836002527	E-Z type HEAT repeats; Region: EZ_HEAT; smart00567
1034836002528	Putative amidase domain; Region: Amidase_6; pfam12671
1034836002529	tRNA (cytidine(34)-2'-O)-methyltransferase; Region: tRNA_yibK_trmL; TIGR00185
1034836002530	Protein of unknown function (DUF4004); Region: DUF4004; pfam13171
1034836002531	Polymer-forming cytoskeletal; Region: Bactofilin; pfam04519
1034836002532	Integral membrane protein CcmA involved in cell shape determination [Cell envelope biogenesis, outer membrane]; Region: CcmA; COG1664
1034836002533	Integral membrane protein CcmA involved in cell shape determination [Cell envelope biogenesis, outer membrane]; Region: CcmA; COG1664
1034836002534	Putative Ser protein kinase [Signal transduction mechanisms]; Region: PrkA; COG2766
1034836002535	PrkA serine protein kinase C-terminal domain; Region: PrkA; pfam06798
1034836002536	sporulation protein YhbH; Region: spore_yhbH; TIGR02877
1034836002537	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1034836002538	MarR family; Region: MarR; pfam01047
1034836002539	Multidrug resistance efflux pump [Defense mechanisms]; Region: EmrA; COG1566
1034836002540	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
1034836002541	carboxyltransferase (CT) interaction site; other site
1034836002542	biotinylation site [posttranslational modification]; other site
1034836002543	HlyD family secretion protein; Region: HlyD_3; pfam13437
1034836002544	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
1034836002545	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1034836002546	putative substrate translocation pore; other site
1034836002547	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1034836002548	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
1034836002549	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
1034836002550	Predicted transcriptional regulators [Transcription]; Region: COG1725
1034836002551	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1034836002552	DNA-binding site [nucleotide binding]; DNA binding site
1034836002553	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1034836002554	gallidermin-class lantibiotic protection ABC transporter, ATP-binding subunit; Region: galliderm_ABC; TIGR03740
1034836002555	Walker A/P-loop; other site
1034836002556	ATP binding site [chemical binding]; other site
1034836002557	Q-loop/lid; other site
1034836002558	ABC transporter signature motif; other site
1034836002559	Walker B; other site
1034836002560	D-loop; other site
1034836002561	H-loop/switch region; other site
1034836002562	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
1034836002563	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1034836002564	Walker A/P-loop; other site
1034836002565	ATP binding site [chemical binding]; other site
1034836002566	Q-loop/lid; other site
1034836002567	ABC transporter signature motif; other site
1034836002568	Walker B; other site
1034836002569	D-loop; other site
1034836002570	H-loop/switch region; other site
1034836002571	ABC-type transport system involved in multi-copper enzyme maturation, permease component [General function prediction only]; Region: NosY; COG1277
1034836002572	ABC-2 family transporter protein; Region: ABC2_membrane_4; pfam12730
1034836002573	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1034836002574	DNA-binding site [nucleotide binding]; DNA binding site
1034836002575	RNA-binding motif; other site
1034836002576	ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism]; Region: NlpA; COG1464
1034836002577	NLPA lipoprotein; Region: Lipoprotein_9; pfam03180
1034836002578	5TMR of 5TMR-LYT; Region: 5TM-5TMR_LYT; pfam07694
1034836002579	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1034836002580	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1034836002581	metal binding site [ion binding]; metal-binding site
1034836002582	active site
1034836002583	I-site; other site
1034836002584	Predicted Na+/dicarboxylate symporter [General function prediction only]; Region: COG1823
1034836002585	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
1034836002586	Zinc peptidases M18, M20, M28, and M42; Region: Zinc_peptidase_like; cl14876
1034836002587	sporulation lipoprotein, YhcN/YlaJ family; Region: spore_YhcN_YlaJ; TIGR02898
1034836002588	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ); Region: Spore_YhcN_YlaJ; pfam09580
1034836002589	Peptidase MA superfamily; Region: Peptidase_MA_2; pfam13485
1034836002590	Spore coat protein [Cell envelope biogenesis, outer membrane]; Region: COG5577
1034836002591	5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases [Nucleotide transport and metabolism]; Region: UshA; COG0737
1034836002592	Bacillus subtilis YhcR endonuclease and related proteins, N-terminal metallophosphatase domain; Region: MPP_YhcR_N; cd07412
1034836002593	putative active site [active]
1034836002594	putative metal binding site [ion binding]; other site
1034836002595	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
1034836002596	Sortase D (SrtD) is a membrane transpeptidase found in gram-positive bacteria that anchors surface proteins to peptidoglycans of the bacterial cell wall envelope. This involves a transpeptidation reaction in which the surface protein substrate is cleaved...; Region: Sortase_D_4; cd05828
1034836002597	active site
1034836002598	catalytic site [active]
1034836002599	pseudouridine synthase, RluA family; Region: rluA_subfam; TIGR00005
1034836002600	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1034836002601	active site
1034836002602	FOG: CBS domain [General function prediction only]; Region: COG0517
1034836002603	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair_9; cd04622
1034836002604	Predicted phosphatase/phosphohexomutase [General function prediction only]; Region: COG0637
1034836002605	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1034836002606	motif II; other site
1034836002607	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
1034836002608	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1034836002609	Coenzyme A binding pocket [chemical binding]; other site
1034836002610	Predicted amidohydrolase [General function prediction only]; Region: COG0388
1034836002611	Uncharacterized subgroup of the nitrilase superfamily; some members of this subgroup have an N-terminal RimI domain (class 12 nitrilases); Region: nitrilase_Rim1_like; cd07574
1034836002612	putative active site [active]
1034836002613	catalytic triad [active]
1034836002614	putative dimer interface [polypeptide binding]; other site
1034836002615	aminotransferase; Validated; Region: PRK07678
1034836002616	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1034836002617	inhibitor-cofactor binding pocket; inhibition site
1034836002618	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1034836002619	catalytic residue [active]
1034836002620	Glycerol-3-phosphate responsive antiterminator (mRNA-binding) [Transcription]; Region: GlpP; COG1954
1034836002621	Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; Region: MIP; cd00333
1034836002622	amphipathic channel; other site
1034836002623	Asn-Pro-Ala signature motifs; other site
1034836002624	glycerol kinase; Provisional; Region: glpK; PRK00047
1034836002625	Escherichia coli glycerol kinase-like proteins; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_EcGK_like; cd07786
1034836002626	N- and C-terminal domain interface [polypeptide binding]; other site
1034836002627	active site
1034836002628	MgATP binding site [chemical binding]; other site
1034836002629	catalytic site [active]
1034836002630	metal binding site [ion binding]; metal-binding site
1034836002631	glycerol binding site [chemical binding]; other site
1034836002632	homotetramer interface [polypeptide binding]; other site
1034836002633	homodimer interface [polypeptide binding]; other site
1034836002634	FBP binding site [chemical binding]; other site
1034836002635	protein IIAGlc interface [polypeptide binding]; other site
1034836002636	Glycerol-3-phosphate dehydrogenase [Energy production and conversion]; Region: GlpA; COG0578
1034836002637	phosphoglucomutase-2-like protein; Provisional; Region: PTZ00150
1034836002638	This CD includes PGM2 (phosphoglucomutase 2) and PGM2L1 (phosphoglucomutase 2-like 1). The mammalian PGM2 is thought to be a phosphopentomutase that catalyzes the conversion of the nucleoside breakdown products, ribose-1-phosphate and...; Region: PGM2; cd05799
1034836002639	active site
1034836002640	substrate binding site [chemical binding]; other site
1034836002641	metal binding site [ion binding]; metal-binding site
1034836002642	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
1034836002643	GAF domain; Region: GAF; pfam01590
1034836002644	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG3920
1034836002645	Histidine kinase; Region: HisKA_3; pfam07730
1034836002646	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1034836002647	ATP binding site [chemical binding]; other site
1034836002648	Mg2+ binding site [ion binding]; other site
1034836002649	G-X-G motif; other site
1034836002650	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1034836002651	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1034836002652	active site
1034836002653	phosphorylation site [posttranslational modification]
1034836002654	intermolecular recognition site; other site
1034836002655	dimerization interface [polypeptide binding]; other site
1034836002656	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1034836002657	DNA binding residues [nucleotide binding]
1034836002658	dimerization interface [polypeptide binding]; other site
1034836002659	Predicted flavoprotein [General function prediction only]; Region: COG0431
1034836002660	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
1034836002661	YhdB-like protein; Region: YhdB; pfam14148
1034836002662	Protein of unknown function (DUF3889); Region: DUF3889; pfam13028
1034836002663	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1034836002664	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1034836002665	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1034836002666	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1034836002667	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
1034836002668	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1034836002669	NlpC/P60 family; Region: NLPC_P60; pfam00877
1034836002670	Transcriptional regulator; Region: Rrf2; cl17282
1034836002671	Rrf2 family protein; Region: rrf2_super; TIGR00738
1034836002672	Conserved TM helix; Region: TM_helix; pfam05552
1034836002673	Conserved TM helix; Region: TM_helix; pfam05552
1034836002674	Conserved TM helix; Region: TM_helix; pfam05552
1034836002675	Uncharacterized conserved protein [Function unknown]; Region: SpoVR; COG2719
1034836002676	SpoVR like protein; Region: SpoVR; pfam04293
1034836002677	Alkaline phosphatase [Inorganic ion transport and metabolism]; Region: PhoA; COG1785
1034836002678	Alkaline phosphatase homologues; alkaline phosphatases are non-specific phosphomonoesterases that catalyze the hydrolysis reaction via a phosphoseryl intermediate to produce inorganic phosphate and the corresponding alcohol, optimally at high pH; Region: alkPPc; cd00016
1034836002679	dimer interface [polypeptide binding]; other site
1034836002680	active site
1034836002681	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1034836002682	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1034836002683	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
1034836002684	NlpC/P60 family; Region: NLPC_P60; pfam00877
1034836002685	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1034836002686	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1034836002687	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1034836002688	dimerization interface [polypeptide binding]; other site
1034836002689	Bacillus subtilis (Bs) citrate synthase CS-I_like. CS catalyzes the condensation of acetyl coenzyme A (AcCoA) and oxalacetate (OAA) to form citrate and coenzyme A (CoA), the first step in the citric acid cycle (TCA or Krebs cycle). 2MCS catalyzes the...; Region: BsCS-I_like; cd06109
1034836002690	dimer interface [polypeptide binding]; other site
1034836002691	Citrate synthase; Region: Citrate_synt; pfam00285
1034836002692	active site
1034836002693	citrylCoA binding site [chemical binding]; other site
1034836002694	oxalacetate/citrate binding site [chemical binding]; other site
1034836002695	coenzyme A binding site [chemical binding]; other site
1034836002696	catalytic triad [active]
1034836002697	short chain dehydrogenase; Provisional; Region: PRK06701
1034836002698	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1034836002699	NAD(P) binding site [chemical binding]; other site
1034836002700	active site
1034836002701	amino acid transporter; Region: 2A0306; TIGR00909
1034836002702	C-terminus of AA_permease; Region: AA_permease_C; pfam13906
1034836002703	solute carrier 6 subfamily, Fusobacterium nucleatum Tyt1-like; solute-binding domain; Region: SLC6sbd_Tyt1-Like; cd10336
1034836002704	putative substrate binding site 2 [chemical binding]; other site
1034836002705	putative substrate binding site 1 [chemical binding]; other site
1034836002706	Na binding site 1 [ion binding]; other site
1034836002707	Na2 binding site [ion binding]; other site
1034836002708	Sigma factor regulator N-terminal; Region: Sigma_reg_N; pfam13800
1034836002709	Sigma factor regulator C-terminal; Region: Sigma_reg_C; pfam13791
1034836002710	RNA polymerase sigma factor SigM; Provisional; Region: PRK09644
1034836002711	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1034836002712	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1034836002713	DNA binding residues [nucleotide binding]
1034836002714	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
1034836002715	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
1034836002716	putative acyl-acceptor binding pocket; other site
1034836002717	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
1034836002718	Domain of unknown function DUF21; Region: DUF21; pfam01595
1034836002719	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1034836002720	Transporter associated domain; Region: CorC_HlyC; smart01091
1034836002721	Helix-Turn-Helix DNA binding domain of transcription regulators from the MerR superfamily; Region: HTH_MerR-SF; cl02600
1034836002722	aspartate aminotransferase; Provisional; Region: PRK06836
1034836002723	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1034836002724	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1034836002725	homodimer interface [polypeptide binding]; other site
1034836002726	catalytic residue [active]
1034836002727	polyketide beta-ketoacyl:acyl carrier protein synthase; Validated; Region: PRK07103
1034836002728	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
1034836002729	dimer interface [polypeptide binding]; other site
1034836002730	active site
1034836002731	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
1034836002732	Domain of unknown function DUF21; Region: DUF21; pfam01595
1034836002733	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1034836002734	Transporter associated domain; Region: CorC_HlyC; smart01091
1034836002735	CrcB-like protein; Region: CRCB; cl09114
1034836002736	CrcB-like protein; Region: CRCB; cl09114
1034836002737	Glycerophosphoryl diester phosphodiesterase [Energy production and conversion]; Region: UgpQ; COG0584
1034836002738	Catalytic domain of phosphoinositide-specific phospholipase C-like phosphodiesterases superfamily; Region: PI-PLCc_GDPD_SF; cl14615
1034836002739	active site
1034836002740	catalytic site [active]
1034836002741	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
1034836002742	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1034836002743	NAD-dependent deacetylase; Provisional; Region: PRK00481
1034836002744	SIR2 family of proteins includes silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation, where the acetyl group from the lysine epsilon-amino group is transferred to the ADP-ribose moiety of NAD+; Region: SIR2-fam; cd01407
1034836002745	NAD+ binding site [chemical binding]; other site
1034836002746	substrate binding site [chemical binding]; other site
1034836002747	Zn binding site [ion binding]; other site
1034836002748	Predicted xylanase/chitin deacetylase [Carbohydrate transport and metabolism]; Region: CDA1; COG0726
1034836002749	Catalytic NodB homology domain of Streptococcus mutans polysaccharide deacetylase PgdA, Bacillus subtilis YheN, and similar proteins; Region: CE4_SmPgdA_like; cd10944
1034836002750	NodB motif; other site
1034836002751	active site
1034836002752	catalytic site [active]
1034836002753	Zn binding site [ion binding]; other site
1034836002754	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
1034836002755	D-Alanine aminotransferase (D-AAT_like): D-amino acid aminotransferase catalyzes transamination between D-amino acids and their respective alpha-keto acids. It plays a major role in the synthesis of bacterial cell wall components like D-alanine and...; Region: D-AAT_like; cd01558
1034836002756	homodimer interface [polypeptide binding]; other site
1034836002757	substrate-cofactor binding pocket; other site
1034836002758	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1034836002759	catalytic residue [active]
1034836002760	transcriptional repressor BetI; Region: betaine_BetI; TIGR03384
1034836002761	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1034836002762	Bacterial transcriptional repressor; Region: TetR_C_6; pfam13977
1034836002763	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1034836002764	Ligand Binding Site [chemical binding]; other site
1034836002765	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1034836002766	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1034836002767	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1034836002768	Walker A/P-loop; other site
1034836002769	ATP binding site [chemical binding]; other site
1034836002770	Q-loop/lid; other site
1034836002771	ABC transporter signature motif; other site
1034836002772	Walker B; other site
1034836002773	D-loop; other site
1034836002774	H-loop/switch region; other site
1034836002775	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1034836002776	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1034836002777	ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Region: ABCC_Glucan_exporter_like; cd03254
1034836002778	Walker A/P-loop; other site
1034836002779	ATP binding site [chemical binding]; other site
1034836002780	Q-loop/lid; other site
1034836002781	ABC transporter signature motif; other site
1034836002782	Walker B; other site
1034836002783	D-loop; other site
1034836002784	H-loop/switch region; other site
1034836002785	biliverdin IX beta reductase (BVR-B, aka flavin reductase)-like proteins; atypical (a) SDRs; Region: BVR-B_like_SDR_a; cd05244
1034836002786	NADH(P)-binding; Region: NAD_binding_10; pfam13460
1034836002787	NAD binding site [chemical binding]; other site
1034836002788	substrate binding site [chemical binding]; other site
1034836002789	putative active site [active]
1034836002790	Small, acid-soluble spore proteins, alpha/beta type; Region: SASP; pfam00269
1034836002791	YheC/D like ATP-grasp; Region: ATPgrasp_YheCD; pfam14398
1034836002792	YheC/D like ATP-grasp; Region: ATPgrasp_YheCD; pfam14398
1034836002793	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4399
1034836002794	hypothetical protein; Provisional; Region: PRK13676
1034836002795	Predicted hydrolases of the HAD superfamily [General function prediction only]; Region: Cof; COG0561
1034836002796	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1034836002797	active site
1034836002798	motif I; other site
1034836002799	motif II; other site
1034836002800	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
1034836002801	coproporphyrinogen III oxidase; Provisional; Region: PRK08207
1034836002802	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1034836002803	FeS/SAM binding site; other site
1034836002804	Lysine/ornithine N-monooxygenase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: IucD; COG3486
1034836002805	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; COG0475
1034836002806	Sodium/hydrogen exchanger family; Region: Na_H_Exchanger; pfam00999
1034836002807	Putative regulatory, ligand-binding protein related to C-terminal domains of K+ channels [Inorganic ion transport and metabolism]; Region: COG0490
1034836002808	TrkA-C domain; Region: TrkA_C; pfam02080
1034836002809	enoyl-CoA hydratase; Provisional; Region: PRK07659
1034836002810	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
1034836002811	substrate binding site [chemical binding]; other site
1034836002812	oxyanion hole (OAH) forming residues; other site
1034836002813	trimer interface [polypeptide binding]; other site
1034836002814	YhzD-like protein; Region: YhzD; pfam14120
1034836002815	ABC-type uncharacterized transport system, ATPase component [General function prediction only]; Region: COG4152
1034836002816	ATP-binding cassette domain of an uncharacterized transporter; Region: ABC_putative_ATPase; cd03269
1034836002817	Walker A/P-loop; other site
1034836002818	ATP binding site [chemical binding]; other site
1034836002819	Q-loop/lid; other site
1034836002820	ABC transporter signature motif; other site
1034836002821	Walker B; other site
1034836002822	D-loop; other site
1034836002823	H-loop/switch region; other site
1034836002824	Domain of unknown function (DUF4162); Region: DUF4162; pfam13732
1034836002825	ABC-type Na+ efflux pump, permease component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatB; COG1668
1034836002826	Mre11 nuclease, N-terminal metallophosphatase domain; Region: MPP_Mre11_N; cd00840
1034836002827	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
1034836002828	active site
1034836002829	metal binding site [ion binding]; metal-binding site
1034836002830	DNA binding site [nucleotide binding]
1034836002831	Uncharacterized conserved protein [Function unknown]; Region: COG4717
1034836002832	3'-5' exoribonuclease YhaM; Provisional; Region: PRK13480
1034836002833	YhaM_OBF_like: A subfamily of OB folds similar to that found in Bacillus subtilis YhaM and Staphylococcus aureus cmp-binding factor-1 (SaCBF1). Both these proteins are 3'-to-5'exoribonucleases. YhaM requires Mn2+ or Co2+ for activity and is...; Region: YhaM_OBF_like; cd04492
1034836002834	generic binding surface II; other site
1034836002835	generic binding surface I; other site
1034836002836	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1034836002837	Zn2+ binding site [ion binding]; other site
1034836002838	Mg2+ binding site [ion binding]; other site
1034836002839	Sporulation protein YhaL; Region: Spore_YhaL; pfam14147
1034836002840	peptidylprolyl isomerase; Provisional; Region: prsA; PRK04405
1034836002841	Bacterial trigger factor protein (TF) C-terminus; Region: Trigger_C; pfam05698
1034836002842	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
1034836002843	Protein of unknown function (DUF3267); Region: DUF3267; pfam11667
1034836002844	Protein of unknown function (DUF1878); Region: DUF1878; pfam08963
1034836002845	transcriptional regulator Hpr; Provisional; Region: PRK13777
1034836002846	MarR family; Region: MarR; pfam01047
1034836002847	Gas vesicle protein [General function prediction only]; Region: GvpP; COG4980
1034836002848	Phosphoserine aminotransferase (PSAT) family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major group in this CD corresponds to phosphoserine aminotransferase (PSAT).  PSAT is active as...; Region: PSAT_like; cd00611
1034836002849	homodimer interface [polypeptide binding]; other site
1034836002850	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
1034836002851	substrate-cofactor binding pocket; other site
1034836002852	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1034836002853	catalytic residue [active]
1034836002854	HINT (histidine triad nucleotide-binding protein) subgroup: Members of this CD belong to the superfamily of histidine triad hydrolases that act on alpha-phosphate of ribonucleotides. This subgroup includes members from all three forms of cellular life; Region: HINT_subgroup; cd01277
1034836002855	HIT family signature motif; other site
1034836002856	catalytic residue [active]
1034836002857	ABC-type Na+ transport system, ATPase component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatA; COG4555
1034836002858	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1034836002859	Walker A/P-loop; other site
1034836002860	ATP binding site [chemical binding]; other site
1034836002861	Q-loop/lid; other site
1034836002862	ABC transporter signature motif; other site
1034836002863	Walker B; other site
1034836002864	D-loop; other site
1034836002865	H-loop/switch region; other site
1034836002866	Bacterial ABC transporter protein EcsB; Region: EcsB; pfam05975
1034836002867	EcsC protein family; Region: EcsC; pfam12787
1034836002868	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
1034836002869	M20 Peptidase Aminoacylase 1 family; Region: M20_Acy1; cd03886
1034836002870	metal binding site [ion binding]; metal-binding site
1034836002871	dimer interface [polypeptide binding]; other site
1034836002872	Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides [General function prediction only]; Region: COG2329
1034836002873	Transglycosylase; Region: Transgly; pfam00912
1034836002874	penicillin-binding protein, 1A family; Region: PBP_1a_fam; TIGR02074
1034836002875	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
1034836002876	Uroporphyrinogen decarboxylase (URO-D) is a dimeric cytosolic enzyme that decarboxylates the four acetate side chains of uroporphyrinogen III (uro-III) to create coproporphyrinogen III, without requiring any prosthetic groups or cofactors. This reaction...; Region: URO-D; cd00717
1034836002877	substrate binding site [chemical binding]; other site
1034836002878	active site
1034836002879	ferrochelatase; Provisional; Region: PRK12435
1034836002880	Ferrochelatase, N-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_N; cd03411
1034836002881	C-terminal domain interface [polypeptide binding]; other site
1034836002882	active site
1034836002883	Ferrochelatase, C-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_C; cd00419
1034836002884	active site
1034836002885	N-terminal domain interface [polypeptide binding]; other site
1034836002886	protoporphyrinogen oxidase; Reviewed; Region: PRK11883
1034836002887	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
1034836002888	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1034836002889	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1034836002890	Predicted membrane protein [Function unknown]; Region: COG1511
1034836002891	YhgE/Pip N-terminal domain; Region: pip_yhgE_Nterm; TIGR03061
1034836002892	YhgE/Pip C-terminal domain; Region: pip_yhgE_Cterm; TIGR03062
1034836002893	3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK12879
1034836002894	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
1034836002895	dimer interface [polypeptide binding]; other site
1034836002896	active site
1034836002897	CoA binding pocket [chemical binding]; other site
1034836002898	Cellulase M and related proteins [Carbohydrate transport and metabolism]; Region: FrvX; COG1363
1034836002899	M42 Peptidase, Endoglucanase-like subfamily; Region: M42_glucanase_like; cd05657
1034836002900	putative oligomer interface [polypeptide binding]; other site
1034836002901	putative active site [active]
1034836002902	metal binding site [ion binding]; metal-binding site
1034836002903	Sodium:dicarboxylate symporter family; Region: SDF; cl00573
1034836002904	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
1034836002905	Metal-dependent hydrolases of the beta-lactamase superfamily III [General function prediction only]; Region: ElaC; COG1234
1034836002906	Lipoate-protein ligase A [Coenzyme metabolism]; Region: LplA; COG0095
1034836002907	lipoyltransferase and lipoate-protein ligase; Region: lipoyltrans; TIGR00545
1034836002908	Bacterial lipoate protein ligase C-terminus; Region: Lip_prot_lig_C; pfam10437
1034836002909	atypical (a) SDRs, subgroup 5; Region: SDR_a5; cd05243
1034836002910	NADH(P)-binding; Region: NAD_binding_10; pfam13460
1034836002911	NAD(P) binding site [chemical binding]; other site
1034836002912	putative active site [active]
1034836002913	long-chain-fatty-acid--CoA ligase; Validated; Region: PRK07656
1034836002914	Prokaryotic long-chain fatty acid CoA synthetases similar to Escherichia coli FadD; Region: FC-FACS_FadD_like; cd05936
1034836002915	acyl-activating enzyme (AAE) consensus motif; other site
1034836002916	putative AMP binding site [chemical binding]; other site
1034836002917	putative active site [active]
1034836002918	putative CoA binding site [chemical binding]; other site
1034836002919	Peptidase family M48; Region: Peptidase_M48; pfam01435
1034836002920	Peptidase inhibitor I9; Region: Inhibitor_I9; pfam05922
1034836002921	Peptidase S8 family domain in Subtilisin proteins; Region: Peptidases_S8_Subtilisin_subset; cd07477
1034836002922	active site
1034836002923	catalytic residues [active]
1034836002924	ABC-type Fe3+-citrate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: FecB; COG4594
1034836002925	Fe3+-siderophore binding domain FhuD.  These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species. They belong to the TroA-like superfamily of helical backbone metal receptor proteins...; Region: FhuD; cd01146
1034836002926	siderophore binding site; other site
1034836002927	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1034836002928	catalytic core [active]
1034836002929	acetyl-CoA acetyltransferase; Provisional; Region: PRK06690
1034836002930	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
1034836002931	dimer interface [polypeptide binding]; other site
1034836002932	active site
1034836002933	acyl-CoA synthetase; Validated; Region: PRK07638
1034836002934	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
1034836002935	acyl-activating enzyme (AAE) consensus motif; other site
1034836002936	Adenylate forming domain, Class I; Region: AFD_class_I; cd04433
1034836002937	acyl-activating enzyme (AAE) consensus motif; other site
1034836002938	active site
1034836002939	AMP binding site [chemical binding]; other site
1034836002940	CoA binding site [chemical binding]; other site
1034836002941	BioY family; Region: BioY; pfam02632
1034836002942	Globin domain present in Globin-Coupled-Sensors (GCS). These domains detect changes in intracellular concentrations of oxygen, carbon monoxyde, or nitrous oxide,  which result in aerotaxis and/or gene regulation. One subgroup, the HemATs, are aerotactic...; Region: sensor_globin; cd01068
1034836002943	heme-binding site [chemical binding]; other site
1034836002944	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1034836002945	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1034836002946	dimer interface [polypeptide binding]; other site
1034836002947	putative CheW interface [polypeptide binding]; other site
1034836002948	putative aminophosphonate oxidoreductase; Region: Phn_aa_oxid; TIGR03329
1034836002949	Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665
1034836002950	Rieske Fe-S protein [Energy production and conversion]; Region: QcrA; COG0723
1034836002951	YhfW family, C-terminal Rieske domain; YhfW is a protein of unknown function with an N-terminal DadA-like (glycine/D-amino acid dehydrogenase) domain and a C-terminal Rieske domain. The Rieske domain is a [2Fe-2S] cluster binding domain involved in...; Region: Rieske_YhfW_C; cd03477
1034836002952	[2Fe-2S] cluster binding site [ion binding]; other site
1034836002953	short chain dehydrogenase; Provisional; Region: PRK06701
1034836002954	classical (c) SDR, subgroup 1; Region: SDR_c1; cd05355
1034836002955	NAD binding site [chemical binding]; other site
1034836002956	metal binding site [ion binding]; metal-binding site
1034836002957	active site
1034836002958	IDEAL domain; Region: IDEAL; pfam08858
1034836002959	Genetic competence transcription factor [Transcription]; Region: ComK; COG4903
1034836002960	Uncharacterized conserved protein [Function unknown]; Region: COG5646
1034836002961	Acetyltransferase (GNAT) domain; Region: Acetyltransf_9; pfam13527
1034836002962	Sterol carrier protein domain; Region: SCP2_2; pfam13530
1034836002963	Uncharacterized proteins similar to Bacillus subtilis YncM; Region: YncM_like; cd13427
1034836002964	putative binding site; other site
1034836002965	putative dimer interface [polypeptide binding]; other site
1034836002966	Excalibur calcium-binding domain; Region: Excalibur; cl05460
1034836002967	Putative heavy-metal-binding; Region: YbjQ_1; cl00426
1034836002968	Predicted symporter [General function prediction only]; Region: DhlC; COG4147
1034836002969	Solute carrier 5 family, sodium/glucose transporters and related proteins; solute-binding domain; Region: SLC5sbd; cd10322
1034836002970	Na binding site [ion binding]; other site
1034836002971	Protein of unknown function (DUF3311); Region: DUF3311; pfam11755
1034836002972	Uncharacterized conserved protein [Function unknown]; Region: COG0398
1034836002973	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
1034836002974	signal peptidase I, bacterial type; Region: sigpep_I_bact; TIGR02227
1034836002975	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
1034836002976	Catalytic site [active]
1034836002977	hypothetical protein; Provisional; Region: PRK08244
1034836002978	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
1034836002979	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1034836002980	MarR family; Region: MarR; pfam01047
1034836002981	membrane protein AbrB duplication; Region: Gneg_AbrB_dup; TIGR03082
1034836002982	Putative ammonia monooxygenase; Region: AmoA; pfam05145
1034836002983	membrane protein AbrB duplication; Region: Gneg_AbrB_dup; TIGR03082
1034836002984	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1034836002985	putative substrate translocation pore; other site
1034836002986	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1034836002987	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1034836002988	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1034836002989	QacR-like protein, C-terminal region; Region: TetR_C_5; pfam08360
1034836002990	Uncharacterized conserved protein [Function unknown]; Region: COG1633
1034836002991	Ferritin-like superfamily of diiron-containing four-helix-bundle proteins; Region: Ferritin_like; cd00657
1034836002992	dinuclear metal binding motif [ion binding]; other site
1034836002993	Predicted membrane protein [Function unknown]; Region: COG2323
1034836002994	helicase-exonuclease AddAB, AddB subunit; Region: addB_Gpos; TIGR02773
1034836002995	PD-(D/E)XK nuclease superfamily; Region: PDDEXK_1; pfam12705
1034836002996	helicase-exonuclease AddAB, AddA subunit, Firmicutes type; Region: addA_Gpos; TIGR02785
1034836002997	Part of AAA domain; Region: AAA_19; pfam13245
1034836002998	Family description; Region: UvrD_C_2; pfam13538
1034836002999	PD-(D/E)XK nuclease superfamily; Region: PDDEXK_1; pfam12705
1034836003000	DNA repair exonuclease [DNA replication, recombination, and repair]; Region: SbcD; COG0420
1034836003001	Mre11 nuclease, N-terminal metallophosphatase domain; Region: MPP_Mre11_N; cd00840
1034836003002	active site
1034836003003	metal binding site [ion binding]; metal-binding site
1034836003004	DNA binding site [nucleotide binding]
1034836003005	Type 5 capsule protein repressor C-terminal domain; Region: SbcD_C; pfam12320
1034836003006	ATP-binding cassette domain of sbcCD; Region: ABC_sbcCD; cd03279
1034836003007	AAA domain; Region: AAA_23; pfam13476
1034836003008	Walker A/P-loop; other site
1034836003009	ATP binding site [chemical binding]; other site
1034836003010	Q-loop/lid; other site
1034836003011	ABC transporter signature motif; other site
1034836003012	ATPase involved in DNA repair [DNA replication, recombination, and repair]; Region: SbcC; COG0419
1034836003013	ATP-binding cassette domain of sbcCD; Region: ABC_sbcCD; cd03279
1034836003014	ABC transporter signature motif; other site
1034836003015	Walker B; other site
1034836003016	D-loop; other site
1034836003017	H-loop/switch region; other site
1034836003018	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cl00083
1034836003019	Spore germination protein gerPA/gerPF; Region: gerPA; pfam10676
1034836003020	Protein of unknown function (DUF2772); Region: DUF2772; pfam10970
1034836003021	Spore germination protein GerPC; Region: GerPC; pfam10737
1034836003022	Protein of unknown function (DUF2539); Region: DUF2539; pfam10803
1034836003023	Spore germination protein gerPA/gerPF; Region: gerPA; pfam10676
1034836003024	Spo0E like sporulation regulatory protein; Region: SpoOE-like; pfam09388
1034836003025	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
1034836003026	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
1034836003027	hypothetical protein; Provisional; Region: PRK13673
1034836003028	Peptidase S8 family domain in Thermitase-like proteins; Region: Peptidases_S8_Thermitase_like; cd07484
1034836003029	active site
1034836003030	catalytic triad [active]
1034836003031	Protein of unknown function (DUF2777); Region: DUF2777; pfam10949
1034836003032	Glutamine amidotransferases class-II (GATase) asparagine synthase_B type.  Asparagine synthetase B catalyses the ATP-dependent conversion of aspartate to asparagine. This enzyme is a homodimer, with each monomer composed of a  glutaminase domain and a...; Region: AsnB; cd00712
1034836003033	active site
1034836003034	asparagine synthase (glutamine-hydrolyzing); Region: asn_synth_AEB; TIGR01536
1034836003035	dimer interface [polypeptide binding]; other site
1034836003036	The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B  catalyzes the...; Region: Asn_Synthase_B_C; cd01991
1034836003037	Ligand Binding Site [chemical binding]; other site
1034836003038	Molecular Tunnel; other site
1034836003039	Phytoene/squalene synthetase [Lipid metabolism]; Region: ERG9; COG1562
1034836003040	substrate binding pocket [chemical binding]; other site
1034836003041	substrate-Mg2+ binding site; other site
1034836003042	aspartate-rich region 1; other site
1034836003043	aspartate-rich region 2; other site
1034836003044	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_like_8; cd13134
1034836003045	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
1034836003046	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
1034836003047	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
1034836003048	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1034836003049	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1034836003050	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1034836003051	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1034836003052	DNA binding site [nucleotide binding]
1034836003053	domain linker motif; other site
1034836003054	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
1034836003055	dimerization interface [polypeptide binding]; other site
1034836003056	ligand binding site [chemical binding]; other site
1034836003057	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1034836003058	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1034836003059	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1034836003060	Uncharacterized protein conserved in bacteria [Function unknown]; Region: DinB; COG2318
1034836003061	Lysine efflux permease [General function prediction only]; Region: COG1279
1034836003062	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
1034836003063	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1034836003064	DNA-binding site [nucleotide binding]; DNA binding site
1034836003065	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1034836003066	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1034836003067	homodimer interface [polypeptide binding]; other site
1034836003068	catalytic residue [active]
1034836003069	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
1034836003070	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
1034836003071	Acetyltransferase (GNAT) domain; Region: Acetyltransf_7; pfam13508
1034836003072	Coenzyme A binding pocket [chemical binding]; other site
1034836003073	bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein; Reviewed; Region: PRK08645
1034836003074	Methionine synthase I (cobalamin-dependent), methyltransferase domain [Amino acid transport and metabolism]; Region: MetH; COG0646
1034836003075	Methylenetetrahydrofolate reductase (MTHFR). 5,10-Methylenetetrahydrofolate is reduced to 5-methyltetrahydrofolate by methylenetetrahydrofolate reductase, a cytoplasmic, NAD(P)-dependent enzyme. 5-methyltetrahydrofolate is utilized by methionine synthase...; Region: MTHFR; cd00537
1034836003076	FAD binding site [chemical binding]; other site
1034836003077	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1666
1034836003078	Proteins similar to Escherichia coli YajQ; Region: YajQ_like; cd11740
1034836003079	Predicted RNA-bindining protein (contains S1 and HTH domains) [General function prediction only]; Region: COG2996
1034836003080	S1 domain; Region: S1_2; pfam13509
1034836003081	Ribosomal protein S1-like RNA-binding domain; Region: S1; smart00316
1034836003082	RNA binding site [nucleotide binding]; other site
1034836003083	Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein [General function prediction only]; Region: Med; COG1744
1034836003084	Periplasmic binding domain of basic membrane lipoprotein, PnrA, in Treponema pallidum and its homologs from other bacteria and Archaea; Region: PBP1_BmpA_PnrA_like; cd06354
1034836003085	ligand binding site [chemical binding]; other site
1034836003086	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1034836003087	dimerization interface [polypeptide binding]; other site
1034836003088	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1034836003089	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1034836003090	dimer interface [polypeptide binding]; other site
1034836003091	putative CheW interface [polypeptide binding]; other site
1034836003092	Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]; Region: CypX; COG2124
1034836003093	Cytochrome P450; Region: p450; cl12078
1034836003094	EDD domain protein, DegV family; Region: DegV; TIGR00762
1034836003095	Uncharacterized protein, DegV family COG1307; Region: DegV; pfam02645
1034836003096	Uncharacterized conserved protein [Function unknown]; Region: COG1284
1034836003097	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
1034836003098	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
1034836003099	Uncharacterized protein conserved in bacteria (DUF2179); Region: DUF2179; pfam10035
1034836003100	Intracellular proteinase inhibitor; Region: BsuPI; pfam12690
1034836003101	Protein of unknown function (DUF3813); Region: DUF3813; pfam12758
1034836003102	Predicted hydrolases of the HAD superfamily [General function prediction only]; Region: Cof; COG0561
1034836003103	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1034836003104	motif II; other site
1034836003105	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1034836003106	esterase; Provisional; Region: PRK10566
1034836003107	Predicted metal-sulfur cluster biosynthetic enzyme [General function prediction only]; Region: PaaD; COG2151
1034836003108	fosfomycin resistance protein FosB; Provisional; Region: PRK04101
1034836003109	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cl14632
1034836003110	active site
1034836003111	metal binding site [ion binding]; metal-binding site
1034836003112	FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277
1034836003113	FAD binding domain; Region: FAD_binding_4; pfam01565
1034836003114	Phosphopentomutase [Carbohydrate transport and metabolism]; Region: DeoB; cl17415
1034836003115	purine nucleoside phosphorylase; Provisional; Region: PRK08202
1034836003116	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
1034836003117	D-alanyl-D-alanine carboxypeptidase [Cell envelope biogenesis, outer membrane]; Region: DacC; COG1686
1034836003118	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; smart00936
1034836003119	anti-sigma F factor antagonist; Region: spore_II_AA; TIGR02886
1034836003120	Anti-sigma regulatory factor (Ser/Thr protein kinase) [Signal transduction mechanisms]; Region: RsbW; COG2172
1034836003121	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1034836003122	ATP binding site [chemical binding]; other site
1034836003123	Mg2+ binding site [ion binding]; other site
1034836003124	G-X-G motif; other site
1034836003125	sporulation sigma factor SigF; Validated; Region: PRK05572
1034836003126	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1034836003127	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
1034836003128	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1034836003129	DNA binding residues [nucleotide binding]
1034836003130	Stage V sporulation protein AA; Region: SporV_AA; pfam12164
1034836003131	Stage V sporulation protein AB; Region: SpoVAB; pfam13782
1034836003132	stage V sporulation protein AC; Region: spore_V_AC; TIGR02838
1034836003133	stage V sporulation protein AD; Validated; Region: PRK08304
1034836003134	stage V sporulation protein AD; Provisional; Region: PRK12404
1034836003135	stage V sporulation protein AE; Region: spore_V_AE; TIGR02839
1034836003136	Stage V sporulation protein AE1; Region: SpoVAE; pfam14097
1034836003137	Bacillus/Clostridium GerA spore germination protein; Region: GerA; pfam03323
1034836003138	diaminopimelate decarboxylase; Region: lysA; TIGR01048
1034836003139	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Diaminopimelate Decarboxylase; Region: PLPDE_III_DapDC; cd06828
1034836003140	active site
1034836003141	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1034836003142	substrate binding site [chemical binding]; other site
1034836003143	catalytic residues [active]
1034836003144	dimer interface [polypeptide binding]; other site
1034836003145	Predicted secreted protein [Function unknown]; Region: COG4086
1034836003146	Protein of unknown function (DUF1002); Region: DUF1002; pfam06207
1034836003147	cyclophilin: cyclophilin-type peptidylprolyl cis- trans isomerases. This family contains eukaryotic, bacterial and archeal proteins which exhibit a peptidylprolyl cis- trans isomerases activity (PPIase, Rotamase) and in addition bind the...; Region: cyclophilin; cd00317
1034836003148	active site
1034836003149	Protein of unknown function (DUF1453); Region: DUF1453; pfam07301
1034836003150	signal peptidase I, bacterial type; Region: sigpep_I_bact; TIGR02227
1034836003151	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
1034836003152	Catalytic site [active]
1034836003153	riboflavin biosynthesis protein RibD; Region: eubact_ribD; TIGR00326
1034836003154	Riboflavin-specific deaminase. Riboflavin biosynthesis protein RibD (Diaminohydroxyphosphoribosylaminopyrimidine deaminase) catalyzes the deamination of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, which is an intermediate step in the...; Region: Riboflavin_deaminase-reductase; cd01284
1034836003155	catalytic motif [active]
1034836003156	Zn binding site [ion binding]; other site
1034836003157	riboflavin-specific deaminase C-terminal domain; Region: ribD_Cterm; TIGR00227
1034836003158	riboflavin synthase subunit alpha; Provisional; Region: PRK09289
1034836003159	Lumazine binding domain; Region: Lum_binding; pfam00677
1034836003160	Lumazine binding domain; Region: Lum_binding; pfam00677
1034836003161	bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein; Provisional; Region: PRK09311
1034836003162	3,4-dihydroxy-2-butanone 4-phosphate synthase; Region: DHBP_synthase; pfam00926
1034836003163	GTP cyclohydrolase II (RibA).  GTP cyclohydrolase II catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5' phosphate, formate, pyrophosphate (APy), and GMP in the biosynthetic pathway of riboflavin. Riboflavin is the...; Region: GTP_cyclohydro2; cd00641
1034836003164	dimerization interface [polypeptide binding]; other site
1034836003165	active site
1034836003166	lumazine synthase (6,7-dimethyl-8-ribityllumazine synthase, LS), catalyzes the penultimate step in the biosynthesis of riboflavin (vitamin B2); type-I; Region: Lumazine_synthase-I; cd09209
1034836003167	homopentamer interface [polypeptide binding]; other site
1034836003168	active site
1034836003169	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1034836003170	Coenzyme A binding pocket [chemical binding]; other site
1034836003171	Domain of unknown function (DUF309); Region: DUF309; cl00667
1034836003172	segregation and condensation protein A; Reviewed; Region: scpA; PRK00104
1034836003173	segregation and condensation protein B; Region: TIGR00281
1034836003174	Protein of unknown function (DUF3907); Region: DUF3907; pfam13047
1034836003175	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
1034836003176	D-alanyl-D-alanine carboxypeptidase [Cell envelope biogenesis, outer membrane]; Region: DacC; COG1686
1034836003177	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; pfam07943
1034836003178	Uncharacterized membrane protein, required for spore maturation in B.subtilis. [General function prediction only]; Region: SpmA; COG2715
1034836003179	Uncharacterized membrane protein [Function unknown]; Region: SpmB; COG0700
1034836003180	16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187
1034836003181	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1034836003182	RNA binding surface [nucleotide binding]; other site
1034836003183	Pseudouridine synthases, RsuA subfamily; Region: PseudoU_synth_RsuA_like; cd02870
1034836003184	active site
1034836003185	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
1034836003186	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
1034836003187	catalytic residues [active]
1034836003188	ResB protein required for cytochrome c biosynthesis [Posttranslational modification, protein turnover, chaperones]; Region: ResB; COG1333
1034836003189	ResB-like family; Region: ResB; pfam05140
1034836003190	Cytochrome C assembly protein; Region: Cytochrom_C_asm; cl00504
1034836003191	Cytochrome C assembly protein; Region: Cytochrom_C_asm; cl00504
1034836003192	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1034836003193	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1034836003194	active site
1034836003195	phosphorylation site [posttranslational modification]
1034836003196	intermolecular recognition site; other site
1034836003197	dimerization interface [polypeptide binding]; other site
1034836003198	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1034836003199	DNA binding site [nucleotide binding]
1034836003200	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: VicK; COG5002
1034836003201	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1034836003202	dimerization interface [polypeptide binding]; other site
1034836003203	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1034836003204	putative active site [active]
1034836003205	heme pocket [chemical binding]; other site
1034836003206	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1034836003207	dimer interface [polypeptide binding]; other site
1034836003208	phosphorylation site [posttranslational modification]
1034836003209	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1034836003210	ATP binding site [chemical binding]; other site
1034836003211	Mg2+ binding site [ion binding]; other site
1034836003212	G-X-G motif; other site
1034836003213	RNA polymerase sigma factor SigX; Provisional; Region: PRK09639
1034836003214	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1034836003215	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1034836003216	DNA binding residues [nucleotide binding]
1034836003217	D-3-phosphoglycerate dehydrogenase; Provisional; Region: PRK13581
1034836003218	Phosphoglycerate dehydrogenases, NAD-binding and catalytic domains; Region: PGDH_4; cd12173
1034836003219	ligand binding site [chemical binding]; other site
1034836003220	NAD binding site [chemical binding]; other site
1034836003221	dimerization interface [polypeptide binding]; other site
1034836003222	catalytic site [active]
1034836003223	C-terminal ACT (regulatory) domain of D-3-phosphoglycerate dehydrogenase (3PGDH); Region: ACT_3PGDH-xct; cd04902
1034836003224	putative L-serine binding site [chemical binding]; other site
1034836003225	Predicted membrane protein [Function unknown]; Region: COG3601
1034836003226	Protein of unknown function (DUF3816); Region: DUF3816; pfam12822
1034836003227	Ferredoxin [Energy production and conversion]; Region: Fer; COG1141
1034836003228	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4955
1034836003229	Superfamily II DNA helicase [DNA replication, recombination, and repair]; Region: RecQ; COG0514
1034836003230	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1034836003231	ATP binding site [chemical binding]; other site
1034836003232	putative Mg++ binding site [ion binding]; other site
1034836003233	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1034836003234	nucleotide binding region [chemical binding]; other site
1034836003235	ATP-binding site [chemical binding]; other site
1034836003236	CAAX protease self-immunity; Region: Abi; pfam02517
1034836003237	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1034836003238	Protein of unknown function (DUF2663); Region: DUF2663; pfam10864
1034836003239	Bacillus subtilis YkuE and related proteins, C-terminal metallophosphatase domain; Region: MPP_YkuE_C; cd07385
1034836003240	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
1034836003241	putative active site [active]
1034836003242	putative metal binding site [ion binding]; other site
1034836003243	adaptor protein; Provisional; Region: PRK02899
1034836003244	Glutamate dehydrogenase/leucine dehydrogenase [Amino acid transport and metabolism]; Region: GdhA; COG0334
1034836003245	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
1034836003246	NAD(P) binding domain of glutamate dehydrogenase, subgroup 1; Region: NAD_bind_1_Glu_DH; cd01076
1034836003247	NAD(P) binding site [chemical binding]; other site
1034836003248	putative bacillithiol system oxidoreductase, YpdA family; Region: Bthiol_YpdA; TIGR04018
1034836003249	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox_3; pfam13738
1034836003250	Membrane proteinase, regulator of anti-sigma factor [Posttranslational modification, protein turnover, chaperones]; Region: prsW; COG2339
1034836003251	spore cortex-lytic enzyme; Region: spore_SleB; TIGR02869
1034836003252	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
1034836003253	Cell Wall Hydrolase; Region: Hydrolase_2; pfam07486
1034836003254	germination protein YpeB; Region: spore_YpeB; TIGR02889
1034836003255	c-di-GMP-binding protein [Signal transduction mechanisms]; Region: COG5581
1034836003256	Flagellar protein YcgR; Region: YcgR_2; pfam12945
1034836003257	PilZ domain; Region: PilZ; pfam07238
1034836003258	cytidylate kinase; Provisional; Region: cmk; PRK00023
1034836003259	Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor; Region: CMPK; cd02020
1034836003260	CMP-binding site; other site
1034836003261	The sites determining sugar specificity; other site
1034836003262	30S ribosomal protein S1; Reviewed; Region: rpsA; PRK06676
1034836003263	S1_RPS1_repeat_ec1_hs1: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec1_hs1; cd05687
1034836003264	RNA binding site [nucleotide binding]; other site
1034836003265	S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465
1034836003266	RNA binding site [nucleotide binding]; other site
1034836003267	S1_RPS1_repeat_ec3: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec3; cd05688
1034836003268	RNA binding site [nucleotide binding]; other site
1034836003269	S1_RPS1_repeat_hs4: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_hs4; cd05692
1034836003270	RNA binding site [nucleotide binding]; other site
1034836003271	isopentenyl pyrophosphate isomerase; Provisional; Region: PRK05437
1034836003272	Isopentenyl-diphosphate:dimethylallyl diphosphate isomerase type 2 (IDI-2) FMN-binding domain. Two types of IDIs have been characterized at present. The long known IDI-1 is only dependent on divalent metals for activity, whereas IDI-2 requires a metal; Region: IDI-2_FMN; cd02811
1034836003273	homotetramer interface [polypeptide binding]; other site
1034836003274	FMN binding site [chemical binding]; other site
1034836003275	homodimer contacts [polypeptide binding]; other site
1034836003276	putative active site [active]
1034836003277	putative substrate binding site [chemical binding]; other site
1034836003278	YpzI-like protein; Region: YpzI; pfam14140
1034836003279	GTP-binding protein Der; Reviewed; Region: PRK00093
1034836003280	EngA1 GTPase contains the first domain of EngA; Region: EngA1; cd01894
1034836003281	G1 box; other site
1034836003282	GTP/Mg2+ binding site [chemical binding]; other site
1034836003283	Switch I region; other site
1034836003284	G2 box; other site
1034836003285	Switch II region; other site
1034836003286	G3 box; other site
1034836003287	G4 box; other site
1034836003288	G5 box; other site
1034836003289	EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895
1034836003290	G1 box; other site
1034836003291	GTP/Mg2+ binding site [chemical binding]; other site
1034836003292	Switch I region; other site
1034836003293	G2 box; other site
1034836003294	G3 box; other site
1034836003295	Switch II region; other site
1034836003296	G4 box; other site
1034836003297	G5 box; other site
1034836003298	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Validated; Region: gpsA; PRK00094
1034836003299	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
1034836003300	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479
1034836003301	Protein of unknown function (DUF2768); Region: DUF2768; pfam10966
1034836003302	Stage IV sporulation protein A (spore_IV_A); Region: Spore_IV_A; pfam09547
1034836003303	stage IV sporulation protein A; Region: spore_IV_A; TIGR02836
1034836003304	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
1034836003305	IHF dimer interface [polypeptide binding]; other site
1034836003306	IHF - DNA interface [nucleotide binding]; other site
1034836003307	GTP cyclohydrolase I (GTP-CH-I) catalyzes the conversion of GTP into dihydroneopterin triphosphate.  The enzyme product is the precursor of tetrahydrofolate in eubacteria, fungi, and plants and of the folate analogs in methanogenic bacteria.  In...; Region: GTP_cyclohydro1; cd00642
1034836003308	homodecamer interface [polypeptide binding]; other site
1034836003309	GTP cyclohydrolase I; Provisional; Region: PLN03044
1034836003310	active site
1034836003311	putative catalytic site residues [active]
1034836003312	zinc binding site [ion binding]; other site
1034836003313	GTP-CH-I/GFRP interaction surface; other site
1034836003314	Tryptophan RNA-binding attenuator protein; Region: TrpBP; pfam02081
1034836003315	Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1; Region: HEPPP_synt_1; pfam07307
1034836003316	ubiE/COQ5 methyltransferase family; Region: Ubie_methyltran; pfam01209
1034836003317	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1034836003318	S-adenosylmethionine binding site [chemical binding]; other site
1034836003319	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
1034836003320	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
1034836003321	substrate binding pocket [chemical binding]; other site
1034836003322	chain length determination region; other site
1034836003323	substrate-Mg2+ binding site; other site
1034836003324	catalytic residues [active]
1034836003325	aspartate-rich region 1; other site
1034836003326	active site lid residues [active]
1034836003327	aspartate-rich region 2; other site
1034836003328	Nucleoside diphosphate kinase Group I (NDPk_I)-like: NDP kinase domains are present in a large family of structurally and functionally conserved proteins from bacteria to humans that generally catalyze the transfer of gamma-phosphates of a nucleoside...; Region: NDPk_I; cd04413
1034836003329	active site
1034836003330	multimer interface [polypeptide binding]; other site
1034836003331	Methylase of chemotaxis methyl-accepting proteins [Cell motility and secretion / Signal transduction mechanisms]; Region: CheR; COG1352
1034836003332	CheR methyltransferase, all-alpha domain; Region: CheR_N; pfam03705
1034836003333	CheR methyltransferase, SAM binding domain; Region: CheR; pfam01739
1034836003334	Chorismate synthase [Amino acid transport and metabolism]; Region: AroC; COG0082
1034836003335	Chorismase synthase, the enzyme catalyzing the final step of the shikimate pathway; Region: Chorismate_synthase; cd07304
1034836003336	Tetramer interface [polypeptide binding]; other site
1034836003337	active site
1034836003338	FMN-binding site [chemical binding]; other site
1034836003339	Dehydroquinate synthase (DHQS) catalyzes the conversion of DAHP to DHQ in shikimate pathway for aromatic compounds synthesis; Region: DHQS; cd08195
1034836003340	active site
1034836003341	dimer interface [polypeptide binding]; other site
1034836003342	metal binding site [ion binding]; metal-binding site
1034836003343	Chorismate mutase (AroH) is one of at least five chorismate-utilizing enzymes present in microorganisms that catalyze the rearrangement of chorismate to prephenic acid, the first committed step in the biosynthesis of aromatic amino acids. In prokaryotes; Region: AroH; cd02185
1034836003344	homotrimer interaction site [polypeptide binding]; other site
1034836003345	active site
1034836003346	anthranilate synthase component I; Provisional; Region: PRK13569
1034836003347	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
1034836003348	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
1034836003349	anthranilate phosphoribosyltransferase; Provisional; Region: trpD; PRK00188
1034836003350	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
1034836003351	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
1034836003352	Indole-3-glycerol phosphate synthase (IGPS); an enzyme in the tryptophan biosynthetic pathway, catalyzing the ring closure reaction of 1-(o-carboxyphenylamino)-1-deoxyribulose-5-phosphate (CdRP) to indole-3-glycerol phosphate (IGP), accompanied by the...; Region: IGPS; cd00331
1034836003353	active site
1034836003354	ribulose/triose binding site [chemical binding]; other site
1034836003355	phosphate binding site [ion binding]; other site
1034836003356	substrate (anthranilate) binding pocket [chemical binding]; other site
1034836003357	product (indole) binding pocket [chemical binding]; other site
1034836003358	Phosphoribosylanthranilate isomerase (PRAI) catalyzes the fourth step of the tryptophan biosynthesis, the conversion of N-(5'- phosphoribosyl)-anthranilate (PRA) to 1-(o-carboxyphenylamino)- 1-deoxyribulose 5-phosphate (CdRP). Most PRAIs are...; Region: PRAI; cd00405
1034836003359	active site
1034836003360	tryptophan synthase, beta subunit; Region: trpB; TIGR00263
1034836003361	Tryptophan synthase-beta:  Trptophan synthase is a bifunctional enzyme that catalyses the last two steps in the biosynthesis of L-tryptophan via its alpha and beta reactions. In the alpha reaction, indole 3-glycerol phosphate is cleaved reversibly to...; Region: Trp-synth_B; cd06446
1034836003362	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1034836003363	catalytic residue [active]
1034836003364	tryptophan synthase alpha subunit; Provisional; Region: trpA; CHL00200
1034836003365	Ttryptophan synthase (TRPS) alpha subunit (TSA). TPRS is a bifunctional tetrameric enzyme (2 alpha and 2 beta subunits) that catalyzes the last two steps of L-tryptophan biosynthesis. Alpha and beta subunit catalyze two distinct reactions which are both...; Region: Tryptophan_synthase_alpha; cd04724
1034836003366	substrate binding site [chemical binding]; other site
1034836003367	active site
1034836003368	catalytic residues [active]
1034836003369	heterodimer interface [polypeptide binding]; other site
1034836003370	histidinol-phosphate aminotransferase; Provisional; Region: PRK03158
1034836003371	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1034836003372	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1034836003373	homodimer interface [polypeptide binding]; other site
1034836003374	catalytic residue [active]
1034836003375	prephenate dehydrogenase; Validated; Region: PRK06545
1034836003376	prephenate dehydrogenase; Validated; Region: PRK08507
1034836003377	C-terminal ACT domain of the monofunctional, NAD dependent, prephenate dehydrogenase (PDH); Region: ACT_PDH-BS; cd04909
1034836003378	3-phosphoshikimate 1-carboxyvinyltransferase; Provisional; Region: PRK02427
1034836003379	EPSP synthase domain. 3-phosphoshikimate 1-carboxyvinyltransferase (5-enolpyruvylshikimate-3-phosphate synthase) (EC 2.5.1.19) catalyses the reaction between shikimate-3-phosphate (S3P) and phosphoenolpyruvate (PEP) to form...; Region: EPSP_synthase; cd01556
1034836003380	hinge; other site
1034836003381	active site
1034836003382	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
1034836003383	TPR motif; other site
1034836003384	binding surface
1034836003385	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1034836003386	binding surface
1034836003387	TPR motif; other site
1034836003388	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1034836003389	TPR motif; other site
1034836003390	binding surface
1034836003391	Anaphase-promoting complex, cyclosome, subunit 3; Region: Apc3; pfam12895
1034836003392	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1034836003393	binding surface
1034836003394	TPR motif; other site
1034836003395	hypothetical protein; Provisional; Region: PRK03636
1034836003396	UPF0302 domain; Region: UPF0302; pfam08864
1034836003397	IDEAL domain; Region: IDEAL; pfam08858
1034836003398	Protein of unknown function (DUF2487); Region: DUF2487; pfam10673
1034836003399	Rieske Fe-S protein [Energy production and conversion]; Region: QcrA; COG0723
1034836003400	Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal; Region: UCR_Fe-S_N; pfam10399
1034836003401	Rieske domain; a [2Fe-2S] cluster binding domain commonly found in Rieske non-heme iron oxygenase (RO) systems such as naphthalene and biphenyl dioxygenases, as well as in plant/cyanobacterial chloroplast b6f and mitochondrial cytochrome bc(1) complexes; Region: Rieske; cd03467
1034836003402	iron-sulfur cluster [ion binding]; other site
1034836003403	[2Fe-2S] cluster binding site [ion binding]; other site
1034836003404	Cytochrome b subunit of the bc complex [Energy production and conversion]; Region: QcrB; COG1290
1034836003405	Cytochrome b (N-terminus)/b6/petB:  Cytochrome b is a subunit of cytochrome bc1, an 11-subunit mitochondrial respiratory enzyme. Cytochrome b spans the mitochondrial membrane with 8 transmembrane helices (A-H) in eukaryotes. In plants and cyanobacteria; Region: Cytochrome_b_N; cd00284
1034836003406	interchain domain interface [polypeptide binding]; other site
1034836003407	intrachain domain interface; other site
1034836003408	heme bH binding site [chemical binding]; other site
1034836003409	Qi binding site; other site
1034836003410	heme bL binding site [chemical binding]; other site
1034836003411	Qo binding site; other site
1034836003412	Qo binding site; other site
1034836003413	Cytochrome b(C-terminus)/b6/petD:  Cytochrome b is a subunit of cytochrome bc1, an 11-subunit mitochondrial respiratory enzyme. Cytochrome b spans the mitochondrial membrane with 8 transmembrane helices (A-H) in eukaryotes. In plants and cyanobacteria; Region: cytochrome_b_C; cl00193
1034836003414	Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010
1034836003415	Cytochrome C oxidase, cbb3-type, subunit III; Region: Cytochrome_CBB3; pfam13442
1034836003416	Protein of unknown function (DUF1405); Region: DUF1405; cl01798
1034836003417	Sporulation protein YpjB (SpoYpjB); Region: Spore_YpjB; pfam09577
1034836003418	bicupin, oxalate decarboxylase family; Region: bicupin_oxalic; TIGR03404
1034836003419	Cupin; Region: Cupin_1; smart00835
1034836003420	Cupin; Region: Cupin_1; smart00835
1034836003421	Uncharacterized conserved protein [Function unknown]; Region: COG1284
1034836003422	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
1034836003423	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
1034836003424	Uncharacterized protein conserved in bacteria (DUF2179); Region: DUF2179; pfam10035
1034836003425	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain putative pyrophosphatase YpjD from Bacillus subtilis and its bacterial homologs; Region: NTP-PPase_BsYpjD; cd11531
1034836003426	homodimer interface [polypeptide binding]; other site
1034836003427	metal binding site [ion binding]; metal-binding site
1034836003428	dihydrodipicolinate reductase; Region: dapB; TIGR00036
1034836003429	Dihydrodipicolinate reductase, N-terminus; Region: DapB_N; pfam01113
1034836003430	Dihydrodipicolinate reductase, C-terminus; Region: DapB_C; pfam05173
1034836003431	Methylglyoxal synthase catalyzes the enolization of dihydroxyacetone phosphate (DHAP) to produce methylglyoxal. The first part of the catalytic mechanism is believed to be similar to TIM (triosephosphate isomerase) in that both enzymes utilize DHAP to...; Region: MGS; cd01422
1034836003432	active site
1034836003433	dimer interfaces [polypeptide binding]; other site
1034836003434	catalytic residues [active]
1034836003435	bacillithiol biosynthesis deacetylase BshB1; Region: thiol_BshB1; TIGR04001
1034836003436	N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA; Region: thiol_BshA; TIGR03999
1034836003437	This family is most closely related to the GT1 family of glycosyltransferases. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can...; Region: GT1_like_5; cd04962
1034836003438	tRNA CCA-pyrophosphorylase; Provisional; Region: PRK13299
1034836003439	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
1034836003440	active site
1034836003441	NTP binding site [chemical binding]; other site
1034836003442	metal binding triad [ion binding]; metal-binding site
1034836003443	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
1034836003444	tRNA nucleotidyltransferase domain 2 putative; Region: tRNA_NucTran2_2; pfam13735
1034836003445	Biotin operon repressor [Transcription]; Region: BirA; COG1654
1034836003446	birA, biotin-[acetyl-CoA-carboxylase] ligase region; Region: birA_ligase; TIGR00121
1034836003447	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; pfam03099
1034836003448	Biotin protein ligase C terminal domain; Region: BPL_C; pfam02237
1034836003449	Ketopantoate hydroxymethyltransferase (KPHMT) is the first enzyme in the pantothenate biosynthesis pathway. Ketopantoate hydroxymethyltransferase (KPHMT) catalyzes the first committed step in the biosynthesis of pantothenate (vitamin B5), which is a...; Region: KPHMT-like; cd06557
1034836003450	oligomerization interface [polypeptide binding]; other site
1034836003451	active site
1034836003452	metal binding site [ion binding]; metal-binding site
1034836003453	Pantoate-beta-alanine ligase; Region: PanC; cd00560
1034836003454	pantoate--beta-alanine ligase; Region: panC; TIGR00018
1034836003455	active site
1034836003456	ATP-binding site [chemical binding]; other site
1034836003457	pantoate-binding site; other site
1034836003458	HXXH motif; other site
1034836003459	Aspartate alpha-decarboxylase or L-aspartate 1-decarboxylase, a pyruvoyl group-dependent  decarboxylase in beta-alanine production; Region: Asp_decarbox; cd06919
1034836003460	tetramerization interface [polypeptide binding]; other site
1034836003461	active site
1034836003462	bifunctional ATP-dependent DNA helicase/DNA polymerase III subunit epsilon; Validated; Region: PRK08074
1034836003463	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
1034836003464	active site
1034836003465	catalytic site [active]
1034836003466	substrate binding site [chemical binding]; other site
1034836003467	Helicase C-terminal domain; Region: Helicase_C_2; pfam13307
1034836003468	Protein of unknown function (DUF4264); Region: DUF4264; pfam14084
1034836003469	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5353
1034836003470	Peptidase propeptide and YPEB domain; Region: PepSY; pfam03413
1034836003471	aspartate aminotransferase; Provisional; Region: PRK05764
1034836003472	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1034836003473	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1034836003474	homodimer interface [polypeptide binding]; other site
1034836003475	catalytic residue [active]
1034836003476	asparaginyl-tRNA synthetase; Validated; Region: asnC; PRK03932
1034836003477	AsnRS_cyto_like_N: N-terminal, anticodon recognition domain of the type found in human and Saccharomyces cerevisiae cytoplasmic asparaginyl-tRNA synthetase (AsnRS), in Brugia malayai AsnRs and, in various putative bacterial AsnRSs.  This domain is a...; Region: AsnRS_cyto_like_N; cd04323
1034836003478	putative dimer interface [polypeptide binding]; other site
1034836003479	putative anticodon binding site; other site
1034836003480	Asx tRNA synthetase (AspRS/AsnRS) class II core domain.  Assignment to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs in the core domain. This family includes AsnRS as well as...; Region: AsxRS_core; cd00776
1034836003481	homodimer interface [polypeptide binding]; other site
1034836003482	motif 1; other site
1034836003483	motif 2; other site
1034836003484	active site
1034836003485	motif 3; other site
1034836003486	Putative primosome component and related proteins [DNA replication, recombination, and repair]; Region: DnaD; COG3935
1034836003487	Replication initiation and membrane attachment; Region: DnaB_2; pfam07261
1034836003488	Predicted EndoIII-related endonuclease [DNA replication, recombination, and repair]; Region: Nth; COG0177
1034836003489	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
1034836003490	minor groove reading motif; other site
1034836003491	helix-hairpin-helix signature motif; other site
1034836003492	substrate binding pocket [chemical binding]; other site
1034836003493	active site
1034836003494	Iron-sulfur binding domain of endonuclease III; Region: EndIII_4Fe-2S; cl15304
1034836003495	Membrane carboxypeptidase (penicillin-binding protein) [Cell envelope biogenesis, outer membrane]; Region: MrcB; COG0744
1034836003496	Transglycosylase; Region: Transgly; pfam00912
1034836003497	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
1034836003498	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
1034836003499	Interdomain contacts; other site
1034836003500	Cytokine receptor motif; other site
1034836003501	Holliday junction-specific endonuclease; Reviewed; Region: recU; PRK02234
1034836003502	Protein of unknown function (DUF2515); Region: DUF2515; pfam10720
1034836003503	Bacterial domain of unknown function (DUF1798); Region: DUF1798; pfam08807
1034836003504	YppF-like protein; Region: YppF; pfam14178
1034836003505	YppG-like protein; Region: YppG; pfam14179
1034836003506	alpha-crystallin domain (ACD) found in alpha-crystallin-type small heat shock proteins, and a similar domain found in p23 (a cochaperone for Hsp90) and in other p23-like proteins; Region: alpha-crystallin-Hsps_p23-like; cl00175
1034836003507	Phosphotransferase system IIA components [Carbohydrate transport and metabolism]; Region: NagE; COG2190
1034836003508	HPr interaction site; other site
1034836003509	glycerol kinase (GK) interaction site [polypeptide binding]; other site
1034836003510	active site
1034836003511	phosphorylation site [posttranslational modification]
1034836003512	Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster [General function prediction only]; Region: COG1205
1034836003513	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1034836003514	ATP binding site [chemical binding]; other site
1034836003515	putative Mg++ binding site [ion binding]; other site
1034836003516	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1034836003517	nucleotide binding region [chemical binding]; other site
1034836003518	ATP-binding site [chemical binding]; other site
1034836003519	Domain of unknown function (DUF1998); Region: DUF1998; pfam09369
1034836003520	Predicted exonuclease [DNA replication, recombination, and repair]; Region: COG3359
1034836003521	RNase_H superfamily; Region: RNase_H_2; pfam13482
1034836003522	active site
1034836003523	substrate binding site [chemical binding]; other site
1034836003524	catalytic site [active]
1034836003525	hypothetical protein; Provisional; Region: PRK13660
1034836003526	cell division protein GpsB; Provisional; Region: PRK14127
1034836003527	DivIVA domain; Region: DivI1A_domain; TIGR03544
1034836003528	Predicted N6-adenine-specific DNA methylase [DNA replication, recombination, and repair]; Region: COG0116
1034836003529	THUMP domain associated with S-adenosylmethionine-dependent methyltransferases; Region: THUMP_AdoMetMT; cd11715
1034836003530	Putative RNA methylase family UPF0020; Region: UPF0020; pfam01170
1034836003531	YpzG-like protein; Region: YpzG; pfam14139
1034836003532	Rad3-related DNA helicases [Transcription / DNA replication, recombination, and repair]; Region: DinG; COG1199
1034836003533	CRISPR/Cas system-associated DinG family helicase Csf4; Region: Csf4_U; cl17460
1034836003534	Helicase C-terminal domain; Region: Helicase_C_2; pfam13307
1034836003535	Zn-dependent carboxypeptidase [Amino acid transport and metabolism]; Region: COG2317
1034836003536	Peptidase family M32 includes thermostable carboxypeptidases TaqCP and PfuCP; Region: M32_Taq; cd06460
1034836003537	active site
1034836003538	Zn binding site [ion binding]; other site
1034836003539	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1034836003540	active site
1034836003541	xanthine permease; Region: pbuX; TIGR03173
1034836003542	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
1034836003543	Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or C-terminal to the catalytic domain. These enzymes perform site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining...; Region: Ser_Recombinase; cd00338
1034836003544	catalytic residues [active]
1034836003545	catalytic nucleophile [active]
1034836003546	Recombinase; Region: Recombinase; pfam07508
1034836003547	Recombinase zinc beta ribbon domain; Region: Zn_ribbon_recom; pfam13408
1034836003548	Staphylococcal nuclease homologues; Region: SNc; smart00318
1034836003549	Staphylococcal nuclease homologues. SNase homologues are found in bacteria, archaea, and eukaryotes. They contain no disufide bonds; Region: SNc; cd00175
1034836003550	Catalytic site; other site
1034836003551	Excalibur calcium-binding domain; Region: Excalibur; smart00894
1034836003552	SMI1 / KNR4 family; Region: SMI1_KNR4; smart00860
1034836003553	LXG domain of WXG superfamily; Region: LXG; pfam04740
1034836003554	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
1034836003555	active site
1034836003556	SMI1 / KNR4 family (SUKH-1); Region: SMI1_KNR4; pfam09346
1034836003557	potential frameshift: common BLAST hit: gi|154687346|ref|YP_001422507.1| YunB
1034836003558	YolD-like protein; Region: YolD; pfam08863
1034836003559	DNA polymerase IV; Reviewed; Region: PRK03103
1034836003560	umuC subunit of DNA Polymerase V; Region: PolY_Pol_V_umuC; cd01700
1034836003561	active site
1034836003562	DNA binding site [nucleotide binding]
1034836003563	potential frameshift: common BLAST hit: gi|323651054|ref|YP_004243697.1| response regulator aspartate phosphatase
1034836003564	Tetratricopeptide repeat; Region: TPR_12; pfam13424
1034836003565	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1034836003566	TPR motif; other site
1034836003567	Tetratricopeptide repeat; Region: TPR_12; pfam13424
1034836003568	binding surface
1034836003569	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
1034836003570	amidase catalytic site [active]
1034836003571	Zn binding residues [ion binding]; other site
1034836003572	substrate binding site [chemical binding]; other site
1034836003573	Bacterial SH3 domain; Region: SH3_3; pfam08239
1034836003574	Probable polygalacturonase At3g15720; Region: PLN03003; cl14103
1034836003575	Pectate lyase superfamily protein; Region: Pectate_lyase_3; pfam12708
1034836003576	Peptidase_G2, IMC autoproteolytic cleavage domain; Region: Peptidase_G2; pfam11962
1034836003577	Prophage endopeptidase tail; Region: Prophage_tail; cl12123
1034836003578	Phage-related protein [Function unknown]; Region: COG4722
1034836003579	Phage tail protein; Region: Sipho_tail; cl17486
1034836003580	potential frameshift: common BLAST hit: gi|221310044|ref|ZP_03591891.1| hypothetical protein Bsubs1_11756
1034836003581	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
1034836003582	Catalytic domain of Protein Kinases; Region: PKc; cd00180
1034836003583	active site
1034836003584	ATP binding site [chemical binding]; other site
1034836003585	substrate binding site [chemical binding]; other site
1034836003586	activation loop (A-loop); other site
1034836003587	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
1034836003588	DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182
1034836003589	active site
1034836003590	catalytic residues [active]
1034836003591	DNA binding site [nucleotide binding]
1034836003592	Int/Topo IB signature motif; other site
1034836003593	Glycerophosphoryl diester phosphodiesterase [Energy production and conversion]; Region: UgpQ; COG0584
1034836003594	Catalytic domain of phosphoinositide-specific phospholipase C-like phosphodiesterases superfamily; Region: PI-PLCc_GDPD_SF; cl14615
1034836003595	active site
1034836003596	catalytic site [active]
1034836003597	Phage uncharacterized protein (Phage_XkdX); Region: Phage_XkdX; cl09900
1034836003598	Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family [Energy production and conversion]; Region: COG1979
1034836003599	ACT domain-containing protein [General function prediction only]; Region: COG1707
1034836003600	Intein/homing endonuclease [DNA replication, recombination, and repair]; Region: COG1372
1034836003601	Hedgehog/Intein domain, found in Hedgehog proteins as well as proteins which contain inteins and undergo protein splicing (e.g. DnaB, RIR1-2, GyrA and Pol). In protein splicing an intervening polypeptide sequence - the intein - is excised from a protein; Region: Hint; cd00081
1034836003602	protein-splicing catalytic site; other site
1034836003603	thioester formation/cholesterol transfer; other site
1034836003604	Hint (Hedgehog/Intein) domain C-terminal region; Region: HintC; smart00305
1034836003605	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
1034836003606	IHF - DNA interface [nucleotide binding]; other site
1034836003607	IHF dimer interface [polypeptide binding]; other site
1034836003608	RNA dependent RNA polymerase; Region: RdRP; pfam05183
1034836003609	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1034836003610	sequence-specific DNA binding site [nucleotide binding]; other site
1034836003611	salt bridge; other site
1034836003612	Tubulin/FtsZ: Family includes tubulin alpha-, beta-, gamma-, delta-, and epsilon-tubulins as well as FtsZ, all of which are involved in polymer formation. Tubulin is the major component of microtubules, but also exists as a heterodimer and as a curved...; Region: Tubulin_FtsZ; cl10017
1034836003613	Tubulin/FtsZ family, GTPase domain; Region: Tubulin; pfam00091
1034836003614	nucleotide binding site [chemical binding]; other site
1034836003615	ORF6C domain; Region: ORF6C; pfam10552
1034836003616	Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair]; Region: UvrD; COG0210
1034836003617	Part of AAA domain; Region: AAA_19; pfam13245
1034836003618	Family description; Region: UvrD_C_2; pfam13538
1034836003619	Phage regulatory protein Rha (Phage_pRha); Region: Phage_pRha; pfam09669
1034836003620	Phage antirepressor protein KilAC domain; Region: ANT; pfam03374
1034836003621	RNase H is an endonuclease that cleaves the RNA strand of an RNA/DNA hybrid in a sequence non-specific manner; Region: RNase_H; cl14782
1034836003622	Predicted acyltransferases [Lipid metabolism]; Region: COG1835
1034836003623	Cro/C1-type HTH DNA-binding domain; Region: HTH_26; pfam13443
1034836003624	HIRAN domain; Region: HIRAN; cl07418
1034836003625	UPF0489 domain; Region: UPF0489; pfam12640
1034836003626	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1034836003627	non-specific DNA binding site [nucleotide binding]; other site
1034836003628	salt bridge; other site
1034836003629	sequence-specific DNA binding site [nucleotide binding]; other site
1034836003630	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1034836003631	active site
1034836003632	DNA binding site [nucleotide binding]
1034836003633	Int/Topo IB signature motif; other site
1034836003634	DNA-sulfur modification-associated; Region: DndB; pfam14072
1034836003635	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1034836003636	salt bridge; other site
1034836003637	non-specific DNA binding site [nucleotide binding]; other site
1034836003638	sequence-specific DNA binding site [nucleotide binding]; other site
1034836003639	Hypothetical protein Yopt; Region: Yopt; pfam09467
1034836003640	SEC7 domain proteins [General function prediction only]; Region: COG5307
1034836003641	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
1034836003642	DNA methylase; Region: N6_N4_Mtase; pfam01555
1034836003643	ATP-dependent DNA ligase; Reviewed; Region: ligB; PRK07636
1034836003644	Adenylation domain of Mycobacterium tuberculosis LigD and LigC-like ATP-dependent DNA ligases; Region: Adenylation_DNA_ligase_LigD_LigC; cd07906
1034836003645	active site
1034836003646	DNA binding site [nucleotide binding]
1034836003647	Uncharacterized conserved protein [Function unknown]; Region: COG2135
1034836003648	YopX protein; Region: YopX; pfam09643
1034836003649	Protein of unknown function (DUF867); Region: DUF867; pfam05908
1034836003650	Pectate lyase superfamily protein; Region: Pectate_lyase_3; pfam12708
1034836003651	Right handed beta helix region; Region: Beta_helix; pfam13229
1034836003652	Periplasmic copper-binding protein (NosD); Region: NosD; pfam05048
1034836003653	Right handed beta helix region; Region: Beta_helix; pfam13229
1034836003654	phosphoprotein phosphatases of the metallophosphatase superfamily, metallophosphatase domain; Region: MPP_PPP_family; cd00144
1034836003655	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
1034836003656	active site
1034836003657	metal binding site [ion binding]; metal-binding site
1034836003658	AAA domain; Region: AAA_24; pfam13479
1034836003659	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
1034836003660	Walker A motif; other site
1034836003661	ATP binding site [chemical binding]; other site
1034836003662	hypothetical protein; Provisional; Region: PRK08624
1034836003663	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
1034836003664	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
1034836003665	active site
1034836003666	metal binding site [ion binding]; metal-binding site
1034836003667	interdomain interaction site; other site
1034836003668	single-stranded-DNA-specific exonuclease RecJ; Region: recJ; TIGR00644
1034836003669	DHH family; Region: DHH; pfam01368
1034836003670	DnaQ-like (or DEDD) 3'-5' exonuclease domain superfamily; Region: DnaQ_like_exo; cl10012
1034836003671	active site
1034836003672	substrate binding site [chemical binding]; other site
1034836003673	Family A polymerase primarily fills DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A; cl02626
1034836003674	active site
1034836003675	DNA binding site [nucleotide binding]
1034836003676	catalytic site [active]
1034836003677	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3584
1034836003678	YorP protein; Region: YorP; pfam09629
1034836003679	ribulose-bisphosphate carboxylase small chain; Region: PLN02289
1034836003680	Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates...; Region: NK; cl17190
1034836003681	AAA domain; Region: AAA_18; pfam13238
1034836003682	active site
1034836003683	5'(3')-deoxyribonucleotidase [Nucleotide transport and metabolism]; Region: COG4502
1034836003684	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
1034836003685	DNA-methyltransferase (dcm); Region: dcm; TIGR00675
1034836003686	cofactor binding site; other site
1034836003687	DNA binding site [nucleotide binding]
1034836003688	substrate interaction site [chemical binding]; other site
1034836003689	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
1034836003690	Protein of unknown function (DUF1653); Region: DUF1653; pfam07866
1034836003691	Ribonucleotide reductase N-terminal; Region: RNR_N; pfam08343
1034836003692	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
1034836003693	Ribonucleotide reductase, barrel domain; Region: Ribonuc_red_lgC; pfam02867
1034836003694	Ribonucleotide reductase, barrel domain; Region: Ribonuc_red_lgC; pfam02867
1034836003695	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
1034836003696	dimer interface [polypeptide binding]; other site
1034836003697	putative radical transfer pathway; other site
1034836003698	diiron center [ion binding]; other site
1034836003699	tyrosyl radical; other site
1034836003700	Peptidyl-tRNA hydrolase PTH2; Region: PTH2; pfam01981
1034836003701	Peptidyl-tRNA hydrolase, type 2 (PTH2)_like . Peptidyl-tRNA hydrolase activity releases tRNA from the premature translation termination product peptidyl-tRNA. Two structurally different enzymes have been reported to encode such activity, Pth present in...; Region: PTH2_family; cl00869
1034836003702	dimer interface [polypeptide binding]; other site
1034836003703	putative active site [active]
1034836003704	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
1034836003705	trimer interface [polypeptide binding]; other site
1034836003706	active site
1034836003707	thymidylate synthase; Reviewed; Region: thyA; PRK01827
1034836003708	Thymidylate synthase and pyrimidine hydroxymethylase: Thymidylate synthase (TS) and deoxycytidylate hydroxymethylase (dCMP-HMase) are homologs that catalyze analogous alkylation of C5 of pyrimidine nucleotides. Both enzymes are involved in the...; Region: TS_Pyrimidine_HMase; cd00351
1034836003709	dimerization interface [polypeptide binding]; other site
1034836003710	active site
1034836003711	Dihydrofolate reductase [Coenzyme metabolism]; Region: FolA; COG0262
1034836003712	Dihydrofolate reductase (DHFR). Reduces 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH as a cofactor. This is an essential step in the biosynthesis of deoxythymidine phosphate since 5,6,7,8-tetrahydrofolate is required to regenerate 5; Region: DHFR; cd00209
1034836003713	folate binding site [chemical binding]; other site
1034836003714	NADP+ binding site [chemical binding]; other site
1034836003715	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1034836003716	sequence-specific DNA binding site [nucleotide binding]; other site
1034836003717	salt bridge; other site
1034836003718	Penicillin-binding protein-related factor A, putative recombinase [General function prediction only]; Region: PrfA; COG3331
1034836003719	xanthine permease; Region: pbuX; TIGR03173
1034836003720	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
1034836003721	DNA binding site [nucleotide binding]
1034836003722	active site
1034836003723	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
1034836003724	Predicted naringenin-chalcone synthase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: BcsA; COG3424
1034836003725	Chalcone and stilbene synthases; plant-specific polyketide synthases (PKS) and related enzymes, also called type III PKSs. PKS generate an array of different products, dependent on the nature of the starter molecule. They share a common chemical strategy; Region: CHS_like; cd00831
1034836003726	malonyl-CoA binding site [chemical binding]; other site
1034836003727	dimer interface [polypeptide binding]; other site
1034836003728	active site
1034836003729	product binding site; other site
1034836003730	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1755
1034836003731	Dynamin-like protein including dynamins, mitofusins, and guanylate-binding proteins; Region: DLP_2; cd09912
1034836003732	Dynamin family; Region: Dynamin_N; pfam00350
1034836003733	G1 box; other site
1034836003734	GTP/Mg2+ binding site [chemical binding]; other site
1034836003735	G2 box; other site
1034836003736	Switch I region; other site
1034836003737	G3 box; other site
1034836003738	Switch II region; other site
1034836003739	G4 box; other site
1034836003740	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
1034836003741	G1 box; other site
1034836003742	GTP/Mg2+ binding site [chemical binding]; other site
1034836003743	Dynamin family; Region: Dynamin_N; pfam00350
1034836003744	G2 box; other site
1034836003745	Switch I region; other site
1034836003746	Dynamin-like protein including dynamins, mitofusins, and guanylate-binding proteins; Region: DLP_2; cd09912
1034836003747	G3 box; other site
1034836003748	Switch II region; other site
1034836003749	GTP/Mg2+ binding site [chemical binding]; other site
1034836003750	G4 box; other site
1034836003751	G5 box; other site
1034836003752	Protein of unknown function (DUF2533); Region: DUF2533; pfam10752
1034836003753	5'-3' exonuclease; Region: 53EXOc; smart00475
1034836003754	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
1034836003755	active site
1034836003756	metal binding site 1 [ion binding]; metal-binding site
1034836003757	putative 5' ssDNA interaction site; other site
1034836003758	metal binding site 3; metal-binding site
1034836003759	metal binding site 2 [ion binding]; metal-binding site
1034836003760	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
1034836003761	putative DNA binding site [nucleotide binding]; other site
1034836003762	putative metal binding site [ion binding]; other site
1034836003763	small, acid-soluble spore protein L; Region: SASP_sspL; TIGR03093
1034836003764	RNAse HI family that includes Archaeal RNase HI; Region: RNase_HI_archaeal_like; cd09279
1034836003765	RNA/DNA hybrid binding site [nucleotide binding]; other site
1034836003766	active site
1034836003767	conserved hypothetical integral membrane protein; Region: TIGR00697
1034836003768	hypothetical protein; Validated; Region: PRK07708
1034836003769	RNAse HI family that includes Archaeal RNase HI; Region: RNase_HI_archaeal_like; cd09279
1034836003770	RNA/DNA hybrid binding site [nucleotide binding]; other site
1034836003771	active site
1034836003772	Protein of unknown function (DUF2602); Region: DUF2602; pfam10782
1034836003773	Protein of unknown function (DUF2564); Region: DUF2564; pfam10819
1034836003774	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1034836003775	DNA-binding site [nucleotide binding]; DNA binding site
1034836003776	RNA-binding motif; other site
1034836003777	diacylglycerol glucosyltransferase; Provisional; Region: PRK13609
1034836003778	Monogalactosyldiacylglycerol (MGDG) synthase; Region: MGDG_synth; pfam06925
1034836003779	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
1034836003780	homoserine O-succinyltransferase; Provisional; Region: PRK05368
1034836003781	Type 1 glutamine amidotransferase (GATase1)-like domain found in homoserine trans-succinylase (HTS); Region: GATase1_HTS; cd03131
1034836003782	proposed active site lysine [active]
1034836003783	conserved cys residue [active]
1034836003784	Glutathione (GSH) peroxidase family; tetrameric selenoenzymes that catalyze the reduction of a variety of hydroperoxides including lipid peroxidases, using GSH as a specific electron donor substrate. GSH peroxidase contains one selenocysteine residue per...; Region: GSH_Peroxidase; cd00340
1034836003785	catalytic residues [active]
1034836003786	dimer interface [polypeptide binding]; other site
1034836003787	Predicted HD superfamily hydrolase [General function prediction only]; Region: COG1418
1034836003788	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1034836003789	Zn2+ binding site [ion binding]; other site
1034836003790	Mg2+ binding site [ion binding]; other site
1034836003791	Scaffold protein Nfu/NifU N terminal; Region: Nfu_N; smart00932
1034836003792	Virulence factor; Region: Virulence_fact; pfam13769
1034836003793	HEAT repeats; Region: HEAT_2; pfam13646
1034836003794	E-Z type HEAT repeats; Region: EZ_HEAT; smart00567
1034836003795	dihydroxy-acid dehydratase; Provisional; Region: PRK00911
1034836003796	Disulphide isomerase; Region: Disulph_isomer; pfam06491
1034836003797	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1034836003798	S-adenosylmethionine binding site [chemical binding]; other site
1034836003799	YpjP-like protein; Region: YpjP; pfam14005
1034836003800	thymidylate synthase; Reviewed; Region: thyA; PRK01827
1034836003801	Thymidylate synthase and pyrimidine hydroxymethylase: Thymidylate synthase (TS) and deoxycytidylate hydroxymethylase (dCMP-HMase) are homologs that catalyze analogous alkylation of C5 of pyrimidine nucleotides. Both enzymes are involved in the...; Region: TS_Pyrimidine_HMase; cd00351
1034836003802	dimerization interface [polypeptide binding]; other site
1034836003803	active site
1034836003804	Dihydrofolate reductase [Coenzyme metabolism]; Region: FolA; COG0262
1034836003805	Dihydrofolate reductase (DHFR). Reduces 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH as a cofactor. This is an essential step in the biosynthesis of deoxythymidine phosphate since 5,6,7,8-tetrahydrofolate is required to regenerate 5; Region: DHFR; cd00209
1034836003806	folate binding site [chemical binding]; other site
1034836003807	NADP+ binding site [chemical binding]; other site
1034836003808	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
1034836003809	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
1034836003810	putative acyl-acceptor binding pocket; other site
1034836003811	Haemolysin-III related; Region: HlyIII; cl03831
1034836003812	channel protein, hemolysin III family; Region: hlyIII; TIGR01065
1034836003813	Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms]; Region: AtoC; COG2204
1034836003814	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1034836003815	Walker A motif; other site
1034836003816	ATP binding site [chemical binding]; other site
1034836003817	Walker B motif; other site
1034836003818	arginine finger; other site
1034836003819	threonine dehydratase; Validated; Region: PRK08639
1034836003820	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
1034836003821	tetramer interface [polypeptide binding]; other site
1034836003822	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1034836003823	catalytic residue [active]
1034836003824	Second of two tandem C-terminal ACT domains of threonine dehydratase I (ThrD-I; L-threonine hydrolyase); Region: ACT_ThrD-I_2; cd04907
1034836003825	putative Ile/Val binding site [chemical binding]; other site
1034836003826	Protein of unknown function (DUF2535); Region: DUF2535; pfam10751
1034836003827	Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems [General function prediction only]; Region: COG1999
1034836003828	SCO (an acronym for Synthesis of Cytochrome c Oxidase) family; composed of proteins similar to Sco1, a membrane-anchored protein possessing a soluble domain with a TRX fold. Members of this family are required for the proper assembly of cytochrome c...; Region: SCO; cd02968
1034836003829	Cu(I) binding site [ion binding]; other site
1034836003830	Members of the SGNH-hydrolase superfamily, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase_YpmR_like; cd04506
1034836003831	active site
1034836003832	catalytic triad [active]
1034836003833	oxyanion hole [active]
1034836003834	Uncharacterized protein conserved in bacteria (DUF2140); Region: DUF2140; pfam09911
1034836003835	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1034836003836	MarR family; Region: MarR; pfam01047
1034836003837	methionine sulfoxide reductase A; Provisional; Region: PRK14054
1034836003838	methionine sulfoxide reductase B; Provisional; Region: PRK00222
1034836003839	SelR domain; Region: SelR; pfam01641
1034836003840	Predicted nucleoside-diphosphate sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG1086
1034836003841	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1034836003842	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
1034836003843	Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or C-terminal to the catalytic domain. These enzymes perform site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining...; Region: Ser_Recombinase; cd00338
1034836003844	catalytic residues [active]
1034836003845	catalytic nucleophile [active]
1034836003846	Recombinase; Region: Recombinase; pfam07508
1034836003847	Recombinase zinc beta ribbon domain; Region: Zn_ribbon_recom; pfam13408
1034836003848	Regulatory protein YrvL; Region: YrvL; pfam14184
1034836003849	L-Lactate 2-monooxygenase (LMO) FMN-binding domain. LMO is a FMN-containing enzyme that catalyzes the conversion of L-lactate and oxygen to acetate, carbon dioxide, and water. LMO is a member of the family of alpha-hydroxy acid oxidases.  It is thought...; Region: LMO_FMN; cd03332
1034836003850	FMN-dependent dehydrogenase; Region: FMN_dh; pfam01070
1034836003851	putative active site [active]
1034836003852	putative substrate binding site [chemical binding]; other site
1034836003853	putative FMN binding site [chemical binding]; other site
1034836003854	putative catalytic residues [active]
1034836003855	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1034836003856	NAD(P) binding site [chemical binding]; other site
1034836003857	active site
1034836003858	Phytase; Region: Phytase; cl17685
1034836003859	DUF based on E. rectale Gene description (DUF3880); Region: DUF3880; pfam12996
1034836003860	Glycosyl transferases group 1; Region: Glyco_trans_1_2; pfam13524
1034836003861	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
1034836003862	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
1034836003863	active site
1034836003864	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1034836003865	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
1034836003866	Coenzyme A binding pocket [chemical binding]; other site
1034836003867	DNA gyrase inhibitor [DNA replication, recombination, and repair]; Region: COG3449
1034836003868	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1034836003869	hypothetical protein; Provisional; Region: PRK06917
1034836003870	inhibitor-cofactor binding pocket; inhibition site
1034836003871	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1034836003872	catalytic residue [active]
1034836003873	Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit [Lipid metabolism]; Region: AtoD; COG1788
1034836003874	3-oxoacid CoA-transferase, B subunit; Region: pcaJ_scoB_fam; TIGR02428
1034836003875	acetylornithine deacetylase; Validated; Region: PRK06915
1034836003876	M20 Peptidases with similarity to acetylornithine deacetylases and succinyl-diaminopimelate desuccinylases; Region: M20_ArgE_DapE_like2; cd03895
1034836003877	metal binding site [ion binding]; metal-binding site
1034836003878	dimer interface [polypeptide binding]; other site
1034836003879	putative beta-lysine N-acetyltransferase; Region: GNAT_ablB; TIGR03827
1034836003880	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1034836003881	Coenzyme A binding pocket [chemical binding]; other site
1034836003882	lysine-2,3-aminomutase; Region: lys_2_3_AblA; TIGR03820
1034836003883	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1034836003884	FeS/SAM binding site; other site
1034836003885	Lysine-2,3-aminomutase; Region: LAM_C; pfam12544
1034836003886	antitoxin MqsA for MqsR toxin; Region: MqsA; cd12870
1034836003887	Zn binding site [ion binding]; other site
1034836003888	toxin interface [polypeptide binding]; other site
1034836003889	hypothetical protein; Provisional; Region: PRK13672
1034836003890	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1034836003891	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_16; cd07263
1034836003892	YozD-like protein; Region: YozD; pfam14162
1034836003893	PAP2_like_2 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase; Region: PAP2_like_2; cd03392
1034836003894	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
1034836003895	active site
1034836003896	YodL-like; Region: YodL; pfam14191
1034836003897	purine nucleoside phosphorylase; Reviewed; Region: deoD; PRK05819
1034836003898	Uridine phosphorylase [Nucleotide transport and metabolism]; Region: Udp; COG2820
1034836003899	D-alanyl-D-alanine carboxypeptidase [Cell envelope biogenesis, outer membrane]; Region: VanY; COG1876
1034836003900	D-alanyl-D-alanine carboxypeptidase; Region: VanY; pfam02557
1034836003901	Methyltransferase domain; Region: Methyltransf_31; pfam13847
1034836003902	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1034836003903	S-adenosylmethionine binding site [chemical binding]; other site
1034836003904	C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526
1034836003905	C-terminal peptidase (prc); Region: prc; TIGR00225
1034836003906	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
1034836003907	protein binding site [polypeptide binding]; other site
1034836003908	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
1034836003909	Catalytic dyad [active]
1034836003910	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
1034836003911	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
1034836003912	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1034836003913	DNA-binding site [nucleotide binding]; DNA binding site
1034836003914	The UbiC transcription regulator-associated (UTRA) domain is a conserved ligand-binding domain; Region: UTRA; smart00866
1034836003915	Glycosyl hydrolase family 1; Region: Glyco_hydro_1; cl01046
1034836003916	beta-galactosidase; Region: BGL; TIGR03356
1034836003917	O-Glycosyl hydrolase [Cell envelope biogenesis, outer membrane]; Region: COG5520
1034836003918	O-Glycosyl hydrolase family 30; Region: Glyco_hydro_30; pfam02055
1034836003919	Solute carrier 5 family, sodium/glucose transporters and related proteins; solute-binding domain; Region: SLC5sbd; cd10322
1034836003920	Na binding site [ion binding]; other site
1034836003921	Protein of unknown function (DUF3311); Region: DUF3311; pfam11755
1034836003922	N-terminal domain of Sphingobium chlorophenolicum 2,6-dichloro-p-hydroquinone 1,2-dioxygenase (PcpA), and similar proteins; Region: PcpA_N_like; cd08346
1034836003923	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1034836003924	Zn binding site [ion binding]; other site
1034836003925	C-terminal domain of Sphingobium chlorophenolicum 2,6-dichloro-p-hydroquinone 1,2-dioxygenase (PcpA), and similar proteins; Region: PcpA_C_like; cd08347
1034836003926	Zn binding site [ion binding]; other site
1034836003927	Predicted esterase [General function prediction only]; Region: COG0400
1034836003928	Nitroreductase-like family 1. A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and...; Region: Nitroreductase_1; cd02137
1034836003929	dimer interface [polypeptide binding]; other site
1034836003930	FMN binding site [chemical binding]; other site
1034836003931	Predicted transcriptional regulators [Transcription]; Region: COG1733
1034836003932	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1034836003933	dimerization interface [polypeptide binding]; other site
1034836003934	putative DNA binding site [nucleotide binding]; other site
1034836003935	putative Zn2+ binding site [ion binding]; other site
1034836003936	4-Oxalocrotonate Tautomerase:  Catalyzes the isomerization of unsaturated ketones. The structure is a homohexamer that is arranged as a trimer of dimers. The hexamer contains six active sites, each formed by residues from three monomers, two from one...; Region: 4Oxalocrotonate_Tautomerase; cl00235
1034836003937	This domain family includes the alpha-crystallin domain (ACD) of alpha-crystallin-type small heat shock proteins (sHsps) and a similar domain found in p23-like proteins.  sHsps are small stress induced proteins with monomeric masses between 12 -43 kDa; Region: ACD_sHsps_p23-like; cd00298
1034836003938	Predicted permeases [General function prediction only]; Region: RarD; COG2962
1034836003939	EamA-like transporter family; Region: EamA; pfam00892
1034836003940	Protein of unknown function (DUF1806); Region: DUF1806; pfam08830
1034836003941	bacillithiol biosynthesis deacetylase BshB2; Region: thiol_BshB2; TIGR04000
1034836003942	Sulphate Transporter and Anti-Sigma factor antagonist domain of the "stressosome" complex proteins RsbS and RsbR, regulators of the bacterial stress activated alternative sigma factor sigma-B by phosphorylation; Region: STAS_RsbR_RsbS_like; cd07041
1034836003943	multidrug efflux protein; Reviewed; Region: PRK01766
1034836003944	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Vibrio cholerae NorM; Region: MATE_NorM_like; cd13131
1034836003945	cation binding site [ion binding]; other site
1034836003946	Uncharacterized conserved protein [Function unknown]; Region: COG1624
1034836003947	Bacterial membrane-spanning protein N-terminus; Region: YojJ; pfam10372
1034836003948	DisA bacterial checkpoint controller nucleotide-binding; Region: DisA_N; pfam02457
1034836003949	This family includes the Gtfs, a group of homologous glycosyltransferases involved in the final stages of the biosynthesis of antibiotics vancomycin and related chloroeremomycin. Gtfs transfer sugar moieties from an activated NDP-sugar donor to the...; Region: GT1_Gtf_like; cd03784
1034836003950	glycosyltransferase, MGT family; Region: MGT; TIGR01426
1034836003951	active site
1034836003952	TDP-binding site; other site
1034836003953	acceptor substrate-binding pocket; other site
1034836003954	homodimer interface [polypeptide binding]; other site
1034836003955	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1034836003956	FOG: LysM repeat [Cell envelope biogenesis, outer membrane]; Region: LytE; COG1388
1034836003957	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1034836003958	FOG: LysM repeat [Cell envelope biogenesis, outer membrane]; Region: LytE; COG1388
1034836003959	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1034836003960	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1034836003961	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
1034836003962	NlpC/P60 family; Region: NLPC_P60; pfam00877
1034836003963	Cu/Zn superoxide dismutase [Inorganic ion transport and metabolism]; Region: SodC; COG2032
1034836003964	Copper/zinc superoxide dismutase (SOD). superoxide dismutases catalyse the conversion of superoxide radicals to molecular oxygen. Three evolutionarily distinct families of SODs are known, of which the copper/zinc-binding family is one. Defects in the...; Region: Cu-Zn_Superoxide_Dismutase; cd00305
1034836003965	E-class dimer interface [polypeptide binding]; other site
1034836003966	P-class dimer interface [polypeptide binding]; other site
1034836003967	active site
1034836003968	Cu2+ binding site [ion binding]; other site
1034836003969	Zn2+ binding site [ion binding]; other site
1034836003970	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1034836003971	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
1034836003972	Walker A motif; other site
1034836003973	ATP binding site [chemical binding]; other site
1034836003974	Walker B motif; other site
1034836003975	arginine finger; other site
1034836003976	CbbQ/NirQ/NorQ C-terminal; Region: CbbQ_C; pfam08406
1034836003977	Nitric oxide reductase activation protein [Inorganic ion transport and metabolism]; Region: NorD; COG4548
1034836003978	norD type: Denitrifying bacteria contain both membrane bound and periplasmic nitrate reductases. Denitrification plays a major role  in completing the nitrogen cycle by converting nitrate or nitrite to nitrogen gas. The pathway for microbial...; Region: vWA_norD_type; cd01454
1034836003979	metal ion-dependent adhesion site (MIDAS); other site
1034836003980	2-oxoglutarate dehydrogenase E1 component; Reviewed; Region: sucA; PRK09404
1034836003981	Thiamine pyrophosphate (TPP) family, E1 of OGDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the 2-oxoglutarate dehydrogenase multienzyme complex (OGDC). OGDC catalyzes the oxidative decarboxylation of...; Region: TPP_E1_OGDC_like; cd02016
1034836003982	TPP-binding site [chemical binding]; other site
1034836003983	Transketolase, pyrimidine binding domain; Region: Transket_pyr; pfam02779
1034836003984	dihydrolipoamide succinyltransferase; Validated; Region: PRK05704
1034836003985	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1034836003986	E3 interaction surface; other site
1034836003987	lipoyl attachment site [posttranslational modification]; other site
1034836003988	e3 binding domain; Region: E3_binding; pfam02817
1034836003989	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
1034836003990	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
1034836003991	Predicted Na+-dependent transporter [General function prediction only]; Region: COG0385
1034836003992	Sodium Bile acid symporter family; Region: SBF; pfam01758
1034836003993	solute carrier 6 subfamily, Fusobacterium nucleatum Tyt1-like; solute-binding domain; Region: SLC6sbd_Tyt1-Like; cd10336
1034836003994	Na2 binding site [ion binding]; other site
1034836003995	putative substrate binding site 1 [chemical binding]; other site
1034836003996	Na binding site 1 [ion binding]; other site
1034836003997	putative substrate binding site 2 [chemical binding]; other site
1034836003998	Superoxide dismutase [Inorganic ion transport and metabolism]; Region: SodA; COG0605
1034836003999	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
1034836004000	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
1034836004001	This group contains class II terpene cyclases, protein prenyltransferases beta subunit, two broadly specific proteinase inhibitors alpha2-macroglobulin (alpha (2)-M) and pregnancy zone protein (PZP) and, the C3 C4 and C5 components of vertebrate...; Region: ISOPREN_C2_like; cl08267
1034836004002	Prenyltransferase-like; Region: Prenyltrans_2; pfam13249
1034836004003	Squalene cyclase [Lipid metabolism]; Region: SqhC; COG1657
1034836004004	ALDH subfamily: ALDH families 1and 2, including 10-formyltetrahydrofolate dehydrogenase, NAD+-dependent retinal dehydrogenase 1 and related proteins; Region: ALDH_F1-2_Ald2-like; cd07091
1034836004005	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
1034836004006	NAD(P) binding site [chemical binding]; other site
1034836004007	catalytic residues [active]
1034836004008	Pleckstrin homology (PH)-like domains in bacteria (PHb); Region: PH-like_bacteria; cd13225
1034836004009	pentamer interface [polypeptide binding]; other site
1034836004010	dodecaamer interface [polypeptide binding]; other site
1034836004011	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
1034836004012	Alpha-crystallin domain (ACD) of alpha-crystallin-type small(s) heat shock proteins (Hsps). sHsps are small stress induced proteins with monomeric masses between 12 -43 kDa, whose common feature is the Alpha-crystallin domain  (ACD). sHsps are generally...; Region: ACD_sHsps-like; cd06464
1034836004013	putative dimer interface [polypeptide binding]; other site
1034836004014	Prokaryotic dksA/traR C4-type zinc finger; Region: zf-dskA_traR; cl00755
1034836004015	azoreductase; Provisional; Region: PRK13556
1034836004016	Superfamily II DNA helicase [DNA replication, recombination, and repair]; Region: RecQ; COG0514
1034836004017	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1034836004018	ATP binding site [chemical binding]; other site
1034836004019	putative Mg++ binding site [ion binding]; other site
1034836004020	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1034836004021	nucleotide binding region [chemical binding]; other site
1034836004022	ATP-binding site [chemical binding]; other site
1034836004023	This DNA-binding domain is found in the RecQ helicase among others and has a helix-turn-helix structure; Region: RQC; smart00956
1034836004024	HRDC domain; Region: HRDC; pfam00570
1034836004025	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1034836004026	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1034836004027	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3584
1034836004028	Microcin C7 self-immunity protein determines resistance to exogenous microcin C7; Region: Peptidase_S66_mccF_like; cd07062
1034836004029	putative dimer interface [polypeptide binding]; other site
1034836004030	catalytic triad [active]
1034836004031	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
1034836004032	Predicted membrane protein [Function unknown]; Region: COG2322
1034836004033	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1034836004034	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1034836004035	catalytic residue [active]
1034836004036	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1034836004037	dimerization interface [polypeptide binding]; other site
1034836004038	putative DNA binding site [nucleotide binding]; other site
1034836004039	putative Zn2+ binding site [ion binding]; other site
1034836004040	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
1034836004041	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1034836004042	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1034836004043	WHG domain; Region: WHG; pfam13305
1034836004044	Cupin domain; Region: Cupin_2; pfam07883
1034836004045	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1034836004046	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1034836004047	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1034836004048	tRNA-binding-domain-containing CsaA-like proteins. CsaA is a molecular chaperone with export related activities. CsaA has a putative tRNA binding activity. The functional unit of CsaA is a homodimer and this domain acts as a dimerization domain; Region: tRNA_bind_CsaA; cd02798
1034836004049	dimer interface [polypeptide binding]; other site
1034836004050	putative tRNA-binding site [nucleotide binding]; other site
1034836004051	Protein of unknown function (DUF1093); Region: DUF1093; pfam06486
1034836004052	MarR family; Region: MarR_2; pfam12802
1034836004053	MarR family; Region: MarR_2; cl17246
1034836004054	Anaerobic dehydrogenases, typically selenocysteine-containing [Energy production and conversion]; Region: BisC; COG0243
1034836004055	The MopB_3 CD includes a group of related uncharacterized bacterial and archaeal molybdopterin-binding oxidoreductase-like domains with a putative N-terminal iron-sulfur [4Fe-4S] cluster binding site and molybdopterin cofactor binding site. These members...; Region: MopB_3; cd02766
1034836004056	putative [4Fe-4S] binding site [ion binding]; other site
1034836004057	putative molybdopterin cofactor binding site [chemical binding]; other site
1034836004058	The MopB_CT_3 CD includes a group of related uncharacterized bacterial molybdopterin-binding oxidoreductase-like domains with a putative N-terminal iron-sulfur [4Fe-4S] cluster binding site and molybdopterin cofactor binding site. This CD is of the...; Region: MopB_CT_3; cd02786
1034836004059	putative molybdopterin cofactor binding site; other site
1034836004060	Phosphoglycerate dehydrogenase and related dehydrogenases [Amino acid transport and metabolism]; Region: SerA; COG0111
1034836004061	Putative D-isomer specific 2-hydroxyacid dehydrogenases; Region: 2-Hacid_dh_10; cd12171
1034836004062	putative ligand binding site [chemical binding]; other site
1034836004063	putative NAD binding site [chemical binding]; other site
1034836004064	catalytic site [active]
1034836004065	Sugar (pentulose and hexulose) kinases [Carbohydrate transport and metabolism]; Region: XylB; COG1070
1034836004066	Autoinducer-2 kinase-like proteins; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_AI-2K_like; cd07798
1034836004067	putative N- and C-terminal domain interface [polypeptide binding]; other site
1034836004068	putative active site [active]
1034836004069	putative MgATP binding site [chemical binding]; other site
1034836004070	catalytic site [active]
1034836004071	metal binding site [ion binding]; metal-binding site
1034836004072	carbohydrate binding site [chemical binding]; other site
1034836004073	polyol permease family; Region: 2A0118; TIGR00897
1034836004074	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1034836004075	putative substrate translocation pore; other site
1034836004076	Bacterial protein of unknown function (DUF948); Region: DUF948; cl01972
1034836004077	3-ketoacyl-(acyl-carrier-protein) reductase; Provisional; Region: fabG; PRK07666
1034836004078	classical (c) SDRs; Region: SDR_c; cd05233
1034836004079	NAD(P) binding site [chemical binding]; other site
1034836004080	active site
1034836004081	Replication terminator protein; Region: RTP; pfam02334
1034836004082	NADP oxidoreductase coenzyme F420-dependent; Region: F420_oxidored; cl17232
1034836004083	Pyrroline-5-carboxylate reductase [Amino acid transport and metabolism]; Region: ProC; COG0345
1034836004084	gamma-glutamyl kinase; Provisional; Region: PRK13402
1034836004085	AAK_G5K_ProB: Glutamate-5-kinase (G5K) catalyzes glutamate-dependent ATP cleavage; G5K transfers the terminal phosphoryl group of ATP to the gamma-carboxyl group of glutamate, in the first and controlling step of proline (and, in mammals, ornithine)...; Region: AAK_G5K_ProB; cd04242
1034836004086	nucleotide binding site [chemical binding]; other site
1034836004087	homotetrameric interface [polypeptide binding]; other site
1034836004088	putative phosphate binding site [ion binding]; other site
1034836004089	putative allosteric binding site; other site
1034836004090	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1034836004091	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1034836004092	The substrate binding domain of LysR-type transcriptional regulator GltC, which activates gltA expression of glutamate synthase operon, contains type 2 periplasmic binding fold; Region: PBP2_GltC_like; cd08434
1034836004093	putative dimerization interface [polypeptide binding]; other site
1034836004094	glutamate synthase subunit alpha; Provisional; Region: gltB; PRK11750
1034836004095	Glutamine amidotransferases class-II (Gn-AT), glutamate synthase (GltS)-type. GltS is a homodimer that synthesizes L-glutamate from 2-oxoglutarate and L-glutamine, an important step in ammonia assimilation in bacteria, cyanobacteria and plants. The...; Region: GltS; cd00713
1034836004096	active site
1034836004097	dimer interface [polypeptide binding]; other site
1034836004098	Glutamate synthase central domain; Region: Glu_syn_central; pfam04898
1034836004099	Glutamate synthase (GltS) FMN-binding domain.  GltS is a complex iron-sulfur flavoprotein that catalyzes the reductive synthesis of L-glutamate from 2-oxoglutarate and L-glutamine via intramolecular channelling of ammonia, a reaction in the plant, yeast...; Region: GltS_FMN; cd02808
1034836004100	active site
1034836004101	FMN binding site [chemical binding]; other site
1034836004102	substrate binding site [chemical binding]; other site
1034836004103	3Fe-4S cluster binding site [ion binding]; other site
1034836004104	gltb_C. This domain is found at the C-terminus of the large subunit (gltB) of glutamate synthase (GltS). GltS encodes a complex iron-sulfur flavoprotein that catalyzes the synthesis of L-glutamate from L-glutamine and 2-oxoglutarate. It requires the...; Region: gltB_C; cd00982
1034836004105	domain interface; other site
1034836004106	glutamate synthases, NADH/NADPH, small subunit; Region: GOGAT_sm_gam; TIGR01317
1034836004107	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1034836004108	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
1034836004109	NADPH:quinone reductase and related Zn-dependent oxidoreductases [Energy production and conversion / General function prediction only]; Region: Qor; COG0604
1034836004110	NAD(P) binding site [chemical binding]; other site
1034836004111	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1034836004112	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1034836004113	The C-terminal substrate binding domain of LysR-type transcriptional regulators, YofA and SoxR, contains the type 2 periplasmic binding fold; Region: PBP2_YofA_SoxR_like; cd08442
1034836004114	putative dimerization interface [polypeptide binding]; other site
1034836004115	threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK00413
1034836004116	TGS _ThrRS_N:  ThrRS (threonyl-tRNA Synthetase)  is a class II tRNA synthetase that couples threonine to its cognate tRNA.  In addition to its catalytic and anticodon-binding domains, ThrRS has an N-terminal TGS domain, named after the ThrRS, GTPase, and...; Region: TGS_ThrRS_N; cd01667
1034836004117	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
1034836004118	Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771
1034836004119	active site
1034836004120	dimer interface [polypeptide binding]; other site
1034836004121	motif 1; other site
1034836004122	motif 2; other site
1034836004123	motif 3; other site
1034836004124	ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860
1034836004125	anticodon binding site; other site
1034836004126	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1034836004127	dimerization interface [polypeptide binding]; other site
1034836004128	putative DNA binding site [nucleotide binding]; other site
1034836004129	putative Zn2+ binding site [ion binding]; other site
1034836004130	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
1034836004131	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1034836004132	putative substrate translocation pore; other site
1034836004133	Gamma-glutamyltransferase [Amino acid transport and metabolism]; Region: Ggt; COG0405
1034836004134	gamma-glutamyltranspeptidase; Region: g_glut_trans; TIGR00066
1034836004135	Helix-turn-helix domain; Region: HTH_17; cl17695
1034836004136	INT_SG3, DNA breaking-rejoining enzymes, integrase/recombinases subgroup 3, catalytic domain. The CD contains various predicted bacterial and phage integrase/recombinase sequences for which not much experimental characterization is available; Region: INT_SG3_C; cd01186
1034836004137	Int/Topo IB signature motif; other site
1034836004138	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Bacillus subtilis yoeA; Region: MATE_yoeA_like; cd13138
1034836004139	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
1034836004140	aldose 1-epimerase superfamily; Region: Aldose_epim; cd01081
1034836004141	active site
1034836004142	catalytic residues [active]
1034836004143	D-Ala-D-Ala carboxypeptidase 3 (S13) family; Region: Peptidase_S13; pfam02113
1034836004144	D-alanyl-D-alanine carboxypeptidase, serine-type, PBP4 family; Region: PBP4; TIGR00666
1034836004145	Condensation domain; Region: Condensation; pfam00668
1034836004146	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
1034836004147	HxxPF-repeated domain; Region: HxxPF_rpt; pfam13745
1034836004148	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
1034836004149	acyl-activating enzyme (AAE) consensus motif; other site
1034836004150	AMP binding site [chemical binding]; other site
1034836004151	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
1034836004152	Condensation domain; Region: Condensation; pfam00668
1034836004153	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
1034836004154	HxxPF-repeated domain; Region: HxxPF_rpt; pfam13745
1034836004155	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
1034836004156	acyl-activating enzyme (AAE) consensus motif; other site
1034836004157	AMP binding site [chemical binding]; other site
1034836004158	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
1034836004159	Condensation domain; Region: Condensation; pfam00668
1034836004160	non-ribosomal peptide synthase domain TIGR01720; Region: NRPS-para261
1034836004161	Condensation domain; Region: Condensation; pfam00668
1034836004162	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
1034836004163	The adenylation domain of nonribosomal peptide synthetases (NRPS), including Bacillus subtilis termination module Surfactin (SrfA-C); Region: A_NRPS_Srf_like; cd12117
1034836004164	acyl-activating enzyme (AAE) consensus motif; other site
1034836004165	AMP binding site [chemical binding]; other site
1034836004166	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
1034836004167	Thioesterase domains of type I polyketide synthases or non-ribosomal peptide synthetases [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3319
1034836004168	Protein of unknown function (DUF1360); Region: DUF1360; pfam07098
1034836004169	Uncharacterized BCR, COG1649; Region: DUF187; pfam02638
1034836004170	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1649
1034836004171	Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960
1034836004172	Short chain acyl-CoA dehydrogenases and eukaryotic short/branched chain acyl-CoA dehydrogenases; Region: SCAD_SBCAD; cd01158
1034836004173	FAD binding site [chemical binding]; other site
1034836004174	homotetramer interface [polypeptide binding]; other site
1034836004175	substrate binding pocket [chemical binding]; other site
1034836004176	catalytic base [active]
1034836004177	AMP-binding domain protein; Validated; Region: PRK08315
1034836004178	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
1034836004179	Uncharacterized subfamily of fatty acid CoA ligase (FACL); Region: FACL_like_2; cd05917
1034836004180	acyl-activating enzyme (AAE) consensus motif; other site
1034836004181	putative AMP binding site [chemical binding]; other site
1034836004182	putative active site [active]
1034836004183	putative CoA binding site [chemical binding]; other site
1034836004184	acetyl-CoA carboxylase biotin carboxylase subunit; Validated; Region: PRK06111
1034836004185	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1034836004186	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
1034836004187	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
1034836004188	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
1034836004189	carboxyltransferase (CT) interaction site; other site
1034836004190	biotinylation site [posttranslational modification]; other site
1034836004191	Isopropylmalate/homocitrate/citramalate synthases [Amino acid transport and metabolism]; Region: LeuA; COG0119
1034836004192	3-hydroxy-3-methylglutaryl-CoA lyase, catalytic TIM barrel domain; Region: DRE_TIM_HMGL; cd07938
1034836004193	active site
1034836004194	catalytic residues [active]
1034836004195	metal binding site [ion binding]; metal-binding site
1034836004196	enoyl-CoA hydratase; Provisional; Region: PRK07657
1034836004197	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
1034836004198	substrate binding site [chemical binding]; other site
1034836004199	oxyanion hole (OAH) forming residues; other site
1034836004200	trimer interface [polypeptide binding]; other site
1034836004201	Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) [Lipid metabolism]; Region: COG4799
1034836004202	Acetyl-CoA carboxylase alpha subunit [Lipid metabolism]; Region: AccA; cl17345
1034836004203	Acetyl-CoA carboxylase alpha subunit [Lipid metabolism]; Region: AccA; cl17345
1034836004204	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1034836004205	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
1034836004206	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
1034836004207	dTDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane]; Region: RfbA; COG1209
1034836004208	active site
1034836004209	tetramer interface; other site
1034836004210	Predicted membrane protein [Function unknown]; Region: COG2246
1034836004211	GtrA-like protein; Region: GtrA; pfam04138
1034836004212	6-carboxyhexanoate--CoA ligase; Provisional; Region: PRK01322
1034836004213	adenosylmethionine--8-amino-7-oxononanoate transaminase; Provisional; Region: PRK06916
1034836004214	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1034836004215	inhibitor-cofactor binding pocket; inhibition site
1034836004216	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1034836004217	catalytic residue [active]
1034836004218	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
1034836004219	KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS); Region: KBL_like; cd06454
1034836004220	substrate-cofactor binding pocket; other site
1034836004221	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1034836004222	catalytic residue [active]
1034836004223	AAA domain; Region: AAA_26; pfam13500
1034836004224	dithiobiotin synthetase; Reviewed; Region: bioD; PRK00090
1034836004225	biotin synthase; Validated; Region: PRK06256
1034836004226	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1034836004227	FeS/SAM binding site; other site
1034836004228	Biotin and Thiamin Synthesis associated domain; Region: BATS; pfam06968
1034836004229	Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]; Region: CypX; COG2124
1034836004230	Cytochrome P450; Region: p450; cl12078
1034836004231	Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit [Lipid metabolism]; Region: AtoD; COG1788
1034836004232	3-oxoacid CoA-transferase, B subunit; Region: pcaJ_scoB_fam; TIGR02428
1034836004233	3-hydroxybutyrate dehydrogenase; Provisional; Region: PRK12429
1034836004234	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1034836004235	NAD(P) binding site [chemical binding]; other site
1034836004236	active site
1034836004237	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
1034836004238	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
1034836004239	Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: CaiC; COG0318
1034836004240	The adenylation domain of nonribosomal peptide synthetases (NRPS) similar to mycosubtilin synthase subunit A (MycA); Region: A_NRPS_MycA_like; cd05908
1034836004241	acyl-activating enzyme (AAE) consensus motif; other site
1034836004242	putative AMP binding site [chemical binding]; other site
1034836004243	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
1034836004244	polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or...; Region: PKS; cd00833
1034836004245	Beta-ketoacyl synthase; Region: PKS_KS; smart00825
1034836004246	active site
1034836004247	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
1034836004248	Glutamate-1-semialdehyde aminotransferase [Coenzyme metabolism]; Region: HemL; COG0001
1034836004249	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1034836004250	inhibitor-cofactor binding pocket; inhibition site
1034836004251	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1034836004252	catalytic residue [active]
1034836004253	Condensation domain; Region: Condensation; pfam00668
1034836004254	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
1034836004255	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
1034836004256	Condensation domain; Region: Condensation; pfam00668
1034836004257	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
1034836004258	HxxPF-repeated domain; Region: HxxPF_rpt; pfam13745
1034836004259	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
1034836004260	acyl-activating enzyme (AAE) consensus motif; other site
1034836004261	AMP binding site [chemical binding]; other site
1034836004262	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
1034836004263	Condensation domain; Region: Condensation; pfam00668
1034836004264	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
1034836004265	HxxPF-repeated domain; Region: HxxPF_rpt; pfam13745
1034836004266	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
1034836004267	amino acid adenylation domain; Region: AA-adenyl-dom; TIGR01733
1034836004268	acyl-activating enzyme (AAE) consensus motif; other site
1034836004269	AMP binding site [chemical binding]; other site
1034836004270	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
1034836004271	Condensation domain; Region: Condensation; pfam00668
1034836004272	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
1034836004273	non-ribosomal peptide synthase domain TIGR01720; Region: NRPS-para261
1034836004274	Condensation domain; Region: Condensation; pfam00668
1034836004275	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
1034836004276	amino acid adenylation domain; Region: AA-adenyl-dom; TIGR01733
1034836004277	acyl-activating enzyme (AAE) consensus motif; other site
1034836004278	AMP binding site [chemical binding]; other site
1034836004279	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
1034836004280	Condensation domain; Region: Condensation; pfam00668
1034836004281	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
1034836004282	non-ribosomal peptide synthase domain TIGR01720; Region: NRPS-para261
1034836004283	Condensation domain; Region: Condensation; pfam00668
1034836004284	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
1034836004285	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
1034836004286	acyl-activating enzyme (AAE) consensus motif; other site
1034836004287	AMP binding site [chemical binding]; other site
1034836004288	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
1034836004289	Condensation domain; Region: Condensation; pfam00668
1034836004290	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
1034836004291	HxxPF-repeated domain; Region: HxxPF_rpt; pfam13745
1034836004292	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
1034836004293	acyl-activating enzyme (AAE) consensus motif; other site
1034836004294	AMP binding site [chemical binding]; other site
1034836004295	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
1034836004296	Condensation domain; Region: Condensation; pfam00668
1034836004297	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
1034836004298	HxxPF-repeated domain; Region: HxxPF_rpt; pfam13745
1034836004299	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
1034836004300	amino acid adenylation domain; Region: AA-adenyl-dom; TIGR01733
1034836004301	acyl-activating enzyme (AAE) consensus motif; other site
1034836004302	AMP binding site [chemical binding]; other site
1034836004303	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
1034836004304	Condensation domain; Region: Condensation; pfam00668
1034836004305	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
1034836004306	non-ribosomal peptide synthase domain TIGR01720; Region: NRPS-para261
1034836004307	Condensation domain; Region: Condensation; pfam00668
1034836004308	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
1034836004309	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
1034836004310	acyl-activating enzyme (AAE) consensus motif; other site
1034836004311	AMP binding site [chemical binding]; other site
1034836004312	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
1034836004313	Thioesterase domains of type I polyketide synthases or non-ribosomal peptide synthetases [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3319
1034836004314	Glycosyl hydrolase family 43; Region: GH43_AXH_1; cd09003
1034836004315	substrate binding site [chemical binding]; other site
1034836004316	active site
1034836004317	Carbohydrate Binding Module 6 (CBM6); many are appended to glycoside hydrolase (GH) family 11 and GH43 xylanase domains; Region: CBM6_xylanase-like; cd04084
1034836004318	metal binding site [ion binding]; metal-binding site
1034836004319	ligand binding site [chemical binding]; other site
1034836004320	O-Glycosyl hydrolase [Cell envelope biogenesis, outer membrane]; Region: COG5520
1034836004321	O-Glycosyl hydrolase family 30; Region: Glyco_hydro_30; pfam02055
1034836004322	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1034836004323	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1034836004324	active site
1034836004325	phosphorylation site [posttranslational modification]
1034836004326	intermolecular recognition site; other site
1034836004327	dimerization interface [polypeptide binding]; other site
1034836004328	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1034836004329	DNA binding site [nucleotide binding]
1034836004330	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1034836004331	HAMP domain; Region: HAMP; pfam00672
1034836004332	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1034836004333	dimer interface [polypeptide binding]; other site
1034836004334	phosphorylation site [posttranslational modification]
1034836004335	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1034836004336	ATP binding site [chemical binding]; other site
1034836004337	Mg2+ binding site [ion binding]; other site
1034836004338	G-X-G motif; other site
1034836004339	YndJ-like protein; Region: YndJ; pfam14158
1034836004340	Domain of unknown function (DUF4166); Region: DUF4166; pfam13761
1034836004341	potential frameshift: common BLAST hit: gi|308173794|ref|YP_003920499.1| YndG
1034836004342	Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115
1034836004343	Sodium:alanine symporter family; Region: Na_Ala_symp; pfam01235
1034836004344	DNA topoisomerase IV, A subunit, Gram-positive; Region: parC_Gpos; TIGR01061
1034836004345	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
1034836004346	CAP-like domain; other site
1034836004347	active site
1034836004348	primary dimer interface [polypeptide binding]; other site
1034836004349	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1034836004350	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1034836004351	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1034836004352	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1034836004353	DNA topoisomerase IV, B subunit, Gram-positive; Region: parE_Gpos; TIGR01058
1034836004354	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1034836004355	ATP binding site [chemical binding]; other site
1034836004356	Mg2+ binding site [ion binding]; other site
1034836004357	G-X-G motif; other site
1034836004358	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
1034836004359	anchoring element; other site
1034836004360	dimer interface [polypeptide binding]; other site
1034836004361	ATP binding site [chemical binding]; other site
1034836004362	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
1034836004363	active site
1034836004364	putative metal-binding site [ion binding]; other site
1034836004365	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
1034836004366	Predicted CoA-binding protein [General function prediction only]; Region: COG1832
1034836004367	putative glycerol-3-phosphate acyltransferase PlsY; Provisional; Region: PRK00220
1034836004368	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4841
1034836004369	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
1034836004370	active site
1034836004371	small acid-soluble spore protein Tlp; Provisional; Region: PRK03830
1034836004372	acid-soluble spore protein N; Provisional; Region: sspN; PRK09398
1034836004373	Protein of unknown function (DUF3901); Region: DUF3901; pfam13040
1034836004374	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
1034836004375	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
1034836004376	catalytic residues [active]
1034836004377	aconitate hydratase; Validated; Region: PRK09277
1034836004378	Aconitase A catalytic domain; Region: AcnA_IRP; cd01586
1034836004379	substrate binding site [chemical binding]; other site
1034836004380	ligand binding site [chemical binding]; other site
1034836004381	Aconitase A swivel domain. This is the major form of the TCA cycle enzyme aconitate hydratase, also known as aconitase and citrate hydro-lyase. It includes bacterial and archaeal aconitase A, and the eukaryotic cytosolic form of aconitase. This group...; Region: AcnA_IRP_Swivel; cd01580
1034836004382	substrate binding site [chemical binding]; other site
1034836004383	acid-soluble spore protein O; Provisional; Region: sspO; PRK02984
1034836004384	acid-soluble spore protein P; Provisional; Region: sspP; PRK09399
1034836004385	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
1034836004386	Protein of unknown function (DUF2621); Region: DUF2621; pfam11084
1034836004387	Protein of unknown function (DUF1453); Region: DUF1453; cl02009
1034836004388	Response regulator receiver domain; Region: Response_reg; pfam00072
1034836004389	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1034836004390	active site
1034836004391	phosphorylation site [posttranslational modification]
1034836004392	intermolecular recognition site; other site
1034836004393	dimerization interface [polypeptide binding]; other site
1034836004394	Cytochrome c biogenesis protein [Posttranslational modification, protein turnover, chaperones]; Region: CcdA; COG0785
1034836004395	Cytochrome C biogenesis protein transmembrane region; Region: DsbD; pfam02683
1034836004396	Spo0E like sporulation regulatory protein; Region: SpoOE-like; pfam09388
1034836004397	hypothetical protein; Provisional; Region: PRK01844
1034836004398	Protein of unknown function (DUF2522); Region: DUF2522; pfam10747
1034836004399	Transketolase [Carbohydrate transport and metabolism]; Region: TktA; COG0021
1034836004400	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
1034836004401	TPP-binding site [chemical binding]; other site
1034836004402	dimer interface [polypeptide binding]; other site
1034836004403	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
1034836004404	PYR/PP interface [polypeptide binding]; other site
1034836004405	dimer interface [polypeptide binding]; other site
1034836004406	TPP binding site [chemical binding]; other site
1034836004407	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1034836004408	Bacterial protein of unknown function (DUF896); Region: DUF896; pfam05979
1034836004409	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
1034836004410	Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or C-terminal to the catalytic domain. These enzymes perform site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining...; Region: Ser_Recombinase; cd00338
1034836004411	catalytic residues [active]
1034836004412	catalytic nucleophile [active]
1034836004413	cell division suppressor protein YneA; Provisional; Region: PRK14125
1034836004414	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1034836004415	LexA repressor; Validated; Region: PRK00215
1034836004416	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1034836004417	putative DNA binding site [nucleotide binding]; other site
1034836004418	putative Zn2+ binding site [ion binding]; other site
1034836004419	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
1034836004420	Catalytic site [active]
1034836004421	Protein of unknown function (DUF2512); Region: DUF2512; pfam10710
1034836004422	The band 7 domain of flotillin (reggie) like proteins. This group contains proteins similar to stomatin, prohibitin, flotillin, HlfK/C and podicin.  Many of these band 7 domain-containing proteins are lipid raft-associated.  Individual proteins of this...; Region: Band_7; cd02106
1034836004423	Protein of unknown function (DUF867); Region: DUF867; pfam05908
1034836004424	Domain of unknown function (DUF4177); Region: DUF4177; pfam13783
1034836004425	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
1034836004426	trimer interface [polypeptide binding]; other site
1034836004427	active site
1034836004428	Predicted membrane protein [Function unknown]; Region: XynA; COG2314
1034836004429	Pectate lyase superfamily protein; Region: Pectate_lyase_3; pfam12708
1034836004430	Peptidase_G2, IMC autoproteolytic cleavage domain; Region: Peptidase_G2; pfam11962
1034836004431	Chitin binding domain; Region: Chitin_bind_3; pfam03067
1034836004432	putative luciferase-like monooxygenase, FMN-dependent, CE1758 family; Region: LLM_CE1758_fam; TIGR04036
1034836004433	Flavin-utilizing monoxygenases; Region: Flavin_utilizing_monoxygenases; cl07892
1034836004434	N5,N10-methylenetetrahydromethanopterin reductase (Mer) catalyzes the reduction of N5,N10-methylenetetrahydromethanopterin with reduced coenzyme F420 to N5-methyltetrahydromethanopterin and oxidized coenzyme F420; Region: Tetrahydromethanopterin_reductase; cd01097
1034836004435	Domain of unknown function (DUF3885); Region: DUF3885; pfam13021
1034836004436	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1034836004437	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
1034836004438	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
1034836004439	YoaP-like; Region: YoaP; pfam14268
1034836004440	Protein of unknown function (DUF4025); Region: DUF4025; pfam13217
1034836004441	ethanol-active dehydrogenase/acetaldehyde-active reductase; Provisional; Region: PRK09422
1034836004442	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD3; cd08297
1034836004443	NAD binding site [chemical binding]; other site
1034836004444	substrate binding site [chemical binding]; other site
1034836004445	catalytic Zn binding site [ion binding]; other site
1034836004446	tetramer interface [polypeptide binding]; other site
1034836004447	structural Zn binding site [ion binding]; other site
1034836004448	DinB family; Region: DinB; cl17821
1034836004449	Tetratricopeptide repeat; Region: TPR_12; pfam13424
1034836004450	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
1034836004451	(2R,3R)-2,3-butanediol dehydrogenase; Region: butanediol_DH_like; cd08233
1034836004452	putative NAD(P) binding site [chemical binding]; other site
1034836004453	catalytic Zn binding site [ion binding]; other site
1034836004454	probable dihydroxyacetone kinase regulator; Region: DHAK_reg; TIGR02366
1034836004455	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1034836004456	phosphoenolpyruvate synthase; Validated; Region: PRK06241
1034836004457	Pyruvate phosphate dikinase, PEP/pyruvate binding domain; Region: PPDK_N; pfam01326
1034836004458	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
1034836004459	Glycosyl hydrolases family 11; Region: Glyco_hydro_11; pfam00457
1034836004460	Escherichia coli xylulokinase-like D-xylulose kinases; a subgroup of the FGGY family of carbohydrate kinases; Region: FGGY_D-XK_EcXK-like; cd07808
1034836004461	N- and C-terminal domain interface [polypeptide binding]; other site
1034836004462	D-xylulose kinase; Region: XylB; TIGR01312
1034836004463	active site
1034836004464	MgATP binding site [chemical binding]; other site
1034836004465	catalytic site [active]
1034836004466	metal binding site [ion binding]; metal-binding site
1034836004467	xylulose binding site [chemical binding]; other site
1034836004468	homodimer interface [polypeptide binding]; other site
1034836004469	xylose isomerase; Provisional; Region: PRK05474
1034836004470	xylose isomerase; Region: xylose_isom_A; TIGR02630
1034836004471	Transcriptional regulators [Transcription]; Region: MarR; COG1846
1034836004472	Winged helix-turn-helix DNA-binding; Region: HTH_24; pfam13412
1034836004473	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
1034836004474	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1034836004475	nucleotide binding site [chemical binding]; other site
1034836004476	Beta-xylosidase [Carbohydrate transport and metabolism]; Region: XynB; COG3507
1034836004477	Glycosyl hydrolase family 43, beta-D-xylosidase; Region: GH43_XYL_1; cd09000
1034836004478	inhibitor binding site; inhibition site
1034836004479	active site
1034836004480	melibiose:sodium symporter; Provisional; Region: PRK10429; cl15392
1034836004481	Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]; Region: CypX; COG2124
1034836004482	Cytochrome P450; Region: p450; cl12078
1034836004483	Uncharacterized conserved protein [Function unknown]; Region: COG5444
1034836004484	GTPase YlqF; Reviewed; Region: rbgA; PRK09563
1034836004485	glutamine synthetase, type I; Region: GlnA; TIGR00653
1034836004486	Glutamine synthetase, beta-Grasp domain; Region: Gln-synt_N; pfam03951
1034836004487	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
1034836004488	Helix-Turn-Helix DNA binding domain of GlnR-like transcription regulators; Region: HTH_GlnR-like; cd01105
1034836004489	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
1034836004490	DNA binding residues [nucleotide binding]
1034836004491	putative dimer interface [polypeptide binding]; other site
1034836004492	Cystathionine beta-lyase family protein involved in aluminum resistance [Inorganic ion transport and metabolism]; Region: COG4100
1034836004493	Aluminium resistance protein; Region: Alum_res; pfam06838
1034836004494	GTP-binding protein HflX; Region: GTP_HflX; TIGR03156
1034836004495	GTP-binding GTPase N-terminal; Region: GTP-bdg_N; pfam13167
1034836004496	HflX GTPase family; Region: HflX; cd01878
1034836004497	G1 box; other site
1034836004498	GTP/Mg2+ binding site [chemical binding]; other site
1034836004499	Switch I region; other site
1034836004500	G2 box; other site
1034836004501	G3 box; other site
1034836004502	Switch II region; other site
1034836004503	G4 box; other site
1034836004504	G5 box; other site
1034836004505	stage V sporulation protein K; Region: spore_V_K; TIGR02881
1034836004506	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1034836004507	Walker A motif; other site
1034836004508	ATP binding site [chemical binding]; other site
1034836004509	Walker B motif; other site
1034836004510	arginine finger; other site
1034836004511	potential frameshift: common BLAST hit: gi|154686154|ref|YP_001421315.1| CwlC
1034836004512	Predicted phosphoesterase (MutT family) [General function prediction only]; Region: COG4112
1034836004513	ribonucleotide-diphosphate reductase subunit beta; Provisional; Region: nrdF2; PRK13966
1034836004514	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
1034836004515	dimer interface [polypeptide binding]; other site
1034836004516	putative radical transfer pathway; other site
1034836004517	diiron center [ion binding]; other site
1034836004518	tyrosyl radical; other site
1034836004519	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK07632
1034836004520	Ribonucleotide reductase N-terminal; Region: RNR_N; pfam08343
1034836004521	Class I ribonucleotide reductase; Region: RNR_I; cd01679
1034836004522	active site
1034836004523	dimer interface [polypeptide binding]; other site
1034836004524	catalytic residues [active]
1034836004525	effector binding site; other site
1034836004526	R2 peptide binding site; other site
1034836004527	ribonucleotide reductase stimulatory protein; Reviewed; Region: nrdI; PRK03600
1034836004528	YmzC-like protein; Region: YmzC; pfam14157
1034836004529	bacterial Hfq-like; Region: Hfq; cd01716
1034836004530	hexamer interface [polypeptide binding]; other site
1034836004531	Sm1 motif; other site
1034836004532	RNA binding site [nucleotide binding]; other site
1034836004533	Sm2 motif; other site
1034836004534	tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed; Region: miaA; PRK00091
1034836004535	tRNA delta(2)-isopentenylpyrophosphate transferase [Translation, ribosomal structure and biogenesis]; Region: MiaA; COG0324
1034836004536	YmaF family; Region: YmaF; pfam12788
1034836004537	Membrane transporters of cations and cationic drugs [Inorganic ion transport and metabolism]; Region: EmrE; COG2076
1034836004538	Membrane transporters of cations and cationic drugs [Inorganic ion transport and metabolism]; Region: EmrE; COG2076
1034836004539	peroxiredoxin, SACOL1771 subfamily; Region: perox_SACOL1771; TIGR03563
1034836004540	Protein of unknown function (DUF867); Region: DUF867; pfam05908
1034836004541	Subtilisin-like serine proteases [Posttranslational modification, protein turnover, chaperones]; Region: AprE; COG1404
1034836004542	Peptidase S8 family domain, uncharacterized subfamily 1; Region: Peptidases_S8_1; cd07487
1034836004543	active site
1034836004544	catalytic triad [active]
1034836004545	Protein of unknown function (DUF1275); Region: DUF1275; pfam06912
1034836004546	Deoxyribonuclease NucA/NucB; Region: DNase_NucA_NucB; pfam14040
1034836004547	Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]; Region: CypX; COG2124
1034836004548	Cytochrome P450; Region: p450; cl12078
1034836004549	Methyltransferase domain; Region: Methyltransf_23; pfam13489
1034836004550	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1034836004551	S-adenosylmethionine binding site [chemical binding]; other site
1034836004552	Phosphopantetheine attachment site; Region: PKS_PP; smart00823
1034836004553	polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or...; Region: PKS; cd00833
1034836004554	Beta-ketoacyl synthase; Region: PKS_KS; smart00825
1034836004555	active site
1034836004556	Phosphopantetheine attachment site; Region: PKS_PP; smart00823
1034836004557	3-oxoacyl-(acyl-carrier-protein) synthase [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: FabB; COG0304
1034836004558	polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or...; Region: PKS; cd00833
1034836004559	active site
1034836004560	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
1034836004561	Thioesterase domains of type I polyketide synthases or non-ribosomal peptide synthetases [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3319
1034836004562	Condensation domain; Region: Condensation; pfam00668
1034836004563	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
1034836004564	HxxPF-repeated domain; Region: HxxPF_rpt; pfam13745
1034836004565	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
1034836004566	acyl-activating enzyme (AAE) consensus motif; other site
1034836004567	AMP binding site [chemical binding]; other site
1034836004568	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
1034836004569	Polyketide synthase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3321
1034836004570	polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or...; Region: PKS; cd00833
1034836004571	active site
1034836004572	Dehydratase domain in polyketide synthase (PKS) enzymes; Region: PKS_DH; smart00826
1034836004573	ketoreductase (KR), subgroup 2, complex (x) SDRs; Region: KR_2_SDR_x; cd08953
1034836004574	putative NADP binding site [chemical binding]; other site
1034836004575	KR domain; Region: KR; pfam08659
1034836004576	active site
1034836004577	Phosphopantetheine attachment site; Region: PKS_PP; smart00823
1034836004578	Polyketide synthase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3321
1034836004579	polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or...; Region: PKS; cd00833
1034836004580	active site
1034836004581	Dehydratase domain in polyketide synthase (PKS) enzymes; Region: PKS_DH; smart00826
1034836004582	ketoreductase (KR), subgroup 2, complex (x) SDRs; Region: KR_2_SDR_x; cd08953
1034836004583	putative NADP binding site [chemical binding]; other site
1034836004584	This enzymatic domain is part of bacterial polyketide synthases; Region: PKS_KR; smart00822
1034836004585	active site
1034836004586	Phosphopantetheine attachment site; Region: PKS_PP; smart00823
1034836004587	Polyketide synthase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3321
1034836004588	polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or...; Region: PKS; cd00833
1034836004589	active site
1034836004590	Dehydratase domain in polyketide synthase (PKS) enzymes; Region: PKS_DH; smart00826
1034836004591	ketoreductase (KR), subgroup 2, complex (x) SDRs; Region: KR_2_SDR_x; cd08953
1034836004592	putative NADP binding site [chemical binding]; other site
1034836004593	This enzymatic domain is part of bacterial polyketide synthases; Region: PKS_KR; smart00822
1034836004594	active site
1034836004595	Dehydratase domain in polyketide synthase (PKS) enzymes; Region: PKS_DH; smart00826
1034836004596	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
1034836004597	polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or...; Region: PKS; cd00833
1034836004598	Polyketide synthase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3321
1034836004599	active site
1034836004600	Dehydratase domain in polyketide synthase (PKS) enzymes; Region: PKS_DH; smart00826
1034836004601	ketoreductase (KR), subgroup 2, complex (x) SDRs; Region: KR_2_SDR_x; cd08953
1034836004602	putative NADP binding site [chemical binding]; other site
1034836004603	This enzymatic domain is part of bacterial polyketide synthases; Region: PKS_KR; smart00822
1034836004604	active site
1034836004605	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1034836004606	Phosphopantetheine attachment site; Region: PKS_PP; smart00823
1034836004607	polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or...; Region: PKS; cd00833
1034836004608	Beta-ketoacyl synthase; Region: PKS_KS; smart00825
1034836004609	active site
1034836004610	ketoreductase (KR), subgroup 2, complex (x) SDRs; Region: KR_2_SDR_x; cd08953
1034836004611	putative NADP binding site [chemical binding]; other site
1034836004612	This enzymatic domain is part of bacterial polyketide synthases; Region: PKS_KR; smart00822
1034836004613	active site
1034836004614	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
1034836004615	Polyketide synthase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3321
1034836004616	polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or...; Region: PKS; cd00833
1034836004617	active site
1034836004618	Dehydratase domain in polyketide synthase (PKS) enzymes; Region: PKS_DH; smart00826
1034836004619	ketoreductase (KR), subgroup 2, complex (x) SDRs; Region: KR_2_SDR_x; cd08953
1034836004620	This enzymatic domain is part of bacterial polyketide synthases; Region: PKS_KR; smart00822
1034836004621	putative NADP binding site [chemical binding]; other site
1034836004622	active site
1034836004623	Phosphopantetheine attachment site; Region: PKS_PP; smart00823
1034836004624	polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or...; Region: PKS; cd00833
1034836004625	Beta-ketoacyl synthase; Region: PKS_KS; smart00825
1034836004626	active site
1034836004627	Phosphopantetheine attachment site; Region: PKS_PP; smart00823
1034836004628	Phosphopantetheine attachment site; Region: PKS_PP; smart00823
1034836004629	polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or...; Region: PKS; cd00833
1034836004630	Beta-ketoacyl synthase; Region: PKS_KS; smart00825
1034836004631	active site
1034836004632	ketoreductase (KR), subgroup 2, complex (x) SDRs; Region: KR_2_SDR_x; cd08953
1034836004633	This enzymatic domain is part of bacterial polyketide synthases; Region: PKS_KR; smart00822
1034836004634	putative NADP binding site [chemical binding]; other site
1034836004635	active site
1034836004636	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
1034836004637	polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or...; Region: PKS; cd00833
1034836004638	Beta-ketoacyl synthase; Region: PKS_KS; smart00825
1034836004639	active site
1034836004640	The adenylation domain (A domain) of a family of nonribosomal peptide synthetases (NRPSs) synthesizing toxins and antitumor agents; Region: A_NRPS_TubE_like; cd05906
1034836004641	Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: CaiC; COG0318
1034836004642	acyl-activating enzyme (AAE) consensus motif; other site
1034836004643	putative AMP binding site [chemical binding]; other site
1034836004644	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
1034836004645	Condensation domain; Region: Condensation; pfam00668
1034836004646	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
1034836004647	HxxPF-repeated domain; Region: HxxPF_rpt; pfam13745
1034836004648	The adenylation domain of nonribosomal peptide synthetases (NRPS), including salinosporamide A polyketide synthase; Region: A_NRPS_Ta1_like; cd12116
1034836004649	acyl-activating enzyme (AAE) consensus motif; other site
1034836004650	AMP binding site [chemical binding]; other site
1034836004651	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
1034836004652	Polyketide synthase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3321
1034836004653	polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or...; Region: PKS; cd00833
1034836004654	active site
1034836004655	Dehydratase domain in polyketide synthase (PKS) enzymes; Region: PKS_DH; smart00826
1034836004656	ketoreductase (KR), subgroup 2, complex (x) SDRs; Region: KR_2_SDR_x; cd08953
1034836004657	This enzymatic domain is part of bacterial polyketide synthases; Region: PKS_KR; smart00822
1034836004658	putative NADP binding site [chemical binding]; other site
1034836004659	active site
1034836004660	Phosphopantetheine attachment site; Region: PKS_PP; smart00823
1034836004661	Phosphopantetheine attachment site; Region: PKS_PP; smart00823
1034836004662	Polyketide synthase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3321
1034836004663	polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or...; Region: PKS; cd00833
1034836004664	active site
1034836004665	ketoreductase (KR), subgroup 2, complex (x) SDRs; Region: KR_2_SDR_x; cd08953
1034836004666	putative NADP binding site [chemical binding]; other site
1034836004667	active site
1034836004668	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
1034836004669	polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or...; Region: PKS; cd00833
1034836004670	Beta-ketoacyl synthase; Region: PKS_KS; smart00825
1034836004671	active site
1034836004672	Enoyl-CoA hydratase/isomerase family; Region: ECH; pfam00378
1034836004673	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
1034836004674	substrate binding site [chemical binding]; other site
1034836004675	oxyanion hole (OAH) forming residues; other site
1034836004676	trimer interface [polypeptide binding]; other site
1034836004677	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
1034836004678	Enoyl-CoA hydratase/isomerase family; Region: ECH; pfam00378
1034836004679	substrate binding site [chemical binding]; other site
1034836004680	oxyanion hole (OAH) forming residues; other site
1034836004681	trimer interface [polypeptide binding]; other site
1034836004682	3-hydroxy-3-methylglutaryl CoA synthase [Lipid metabolism]; Region: PksG; COG3425
1034836004683	"initiating" condensing enzymes are a subclass of decarboxylating condensing enzymes, including beta-ketoacyl [ACP] synthase, type III and polyketide synthases, type III, which include chalcone synthase and related enzymes. They are...; Region: init_cond_enzymes; cd00827
1034836004684	dimer interface [polypeptide binding]; other site
1034836004685	active site
1034836004686	acyl carrier protein; Validated; Region: PRK07117
1034836004687	potential frameshift: common BLAST hit: gi|154686126|ref|YP_001421287.1| BaeE
1034836004688	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
1034836004689	Acyl transferase domain in polyketide synthase (PKS) enzymes; Region: PKS_AT; smart00827
1034836004690	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
1034836004691	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
1034836004692	Metallo-beta-lactamase superfamily; Region: Lactamase_B; cl00446
1034836004693	DNA mismatch repair protein; Reviewed; Region: mutL; PRK00095
1034836004694	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1034836004695	ATP binding site [chemical binding]; other site
1034836004696	Mg2+ binding site [ion binding]; other site
1034836004697	G-X-G motif; other site
1034836004698	MutL_Trans: transducer domain, having a ribosomal S5 domain 2-like fold, conserved in the C-terminal domain of DNA mismatch repair (MutL/MLH1/PMS2) family. This transducer domain is homologous to the second domain of the DNA gyrase B subunit, which is...; Region: MutL_Trans; cd00782
1034836004699	ATP binding site [chemical binding]; other site
1034836004700	MutL C terminal dimerisation domain; Region: MutL_C; pfam08676
1034836004701	DNA mismatch repair protein MutS; Provisional; Region: PRK05399
1034836004702	MutS domain I; Region: MutS_I; pfam01624
1034836004703	MutS domain II; Region: MutS_II; pfam05188
1034836004704	MutS domain III; Region: MutS_III; pfam05192
1034836004705	ATP-binding cassette domain of MutS1 homolog; Region: ABC_MutS1; cd03284
1034836004706	Walker A/P-loop; other site
1034836004707	ATP binding site [chemical binding]; other site
1034836004708	Q-loop/lid; other site
1034836004709	ABC transporter signature motif; other site
1034836004710	Walker B; other site
1034836004711	D-loop; other site
1034836004712	H-loop/switch region; other site
1034836004713	Outer spore coat protein E (CotE); Region: CotE; pfam10628
1034836004714	Predicted membrane protein [Function unknown]; Region: COG4550
1034836004715	(dimethylallyl)adenosine tRNA methylthiotransferase; Provisional; Region: PRK14327
1034836004716	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
1034836004717	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1034836004718	FeS/SAM binding site; other site
1034836004719	TRAM domain; Region: TRAM; pfam01938
1034836004720	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
1034836004721	KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS); Region: KBL_like; cd06454
1034836004722	substrate-cofactor binding pocket; other site
1034836004723	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1034836004724	catalytic residue [active]
1034836004725	Threonine dehydrogenase; Region: TDH; cd05281
1034836004726	L-threonine 3-dehydrogenase; Validated; Region: tdh; PRK05396
1034836004727	structural Zn binding site [ion binding]; other site
1034836004728	catalytic Zn binding site [ion binding]; other site
1034836004729	tetramer interface [polypeptide binding]; other site
1034836004730	NADP binding site [chemical binding]; other site
1034836004731	Stage V sporulation protein S (SpoVS); Region: SpoVS; pfam04232
1034836004732	Deinococcus radiodurans DR1281 and related proteins, metallophosphatase domain; Region: MPP_DR1281; cd07382
1034836004733	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
1034836004734	putative active site [active]
1034836004735	metal binding site [ion binding]; metal-binding site
1034836004736	homodimer binding site [polypeptide binding]; other site
1034836004737	Domain of unknown function (DUF3552); Region: DUF3552; pfam12072
1034836004738	Predicted HD superfamily hydrolase [General function prediction only]; Region: COG1418
1034836004739	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1034836004740	Zn2+ binding site [ion binding]; other site
1034836004741	Mg2+ binding site [ion binding]; other site
1034836004742	Beta-lactamase; Region: Beta-lactamase; pfam00144
1034836004743	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
1034836004744	recombinase A; Provisional; Region: recA; PRK09354
1034836004745	RecA is a  bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response.  RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983
1034836004746	hexamer interface [polypeptide binding]; other site
1034836004747	Walker A motif; other site
1034836004748	ATP binding site [chemical binding]; other site
1034836004749	Walker B motif; other site
1034836004750	competence damage-inducible protein A; Provisional; Region: PRK00549
1034836004751	Competence-damaged protein. CinA is the first gene in the competence- inducible (cin) operon and is thought to be specifically required at some stage in the process of transformation. This domain is closely related to a domain, found in a variety of...; Region: cinA; cd00885
1034836004752	putative MPT binding site; other site
1034836004753	Competence-damaged protein; Region: CinA; pfam02464
1034836004754	CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Region: pgsA; TIGR00560
1034836004755	Predicted transcriptional regulator contains Xre-like HTH domain [Function unknown]; Region: COG1426
1034836004756	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1034836004757	non-specific DNA binding site [nucleotide binding]; other site
1034836004758	salt bridge; other site
1034836004759	sequence-specific DNA binding site [nucleotide binding]; other site
1034836004760	Domain of unknown function (DUF4115); Region: DUF4115; pfam13464
1034836004761	ACT domain; Region: ACT; pfam01842
1034836004762	Protein of unknown function (DUF3388); Region: DUF3388; pfam11868
1034836004763	Protein of unknown function (DUF3243); Region: DUF3243; pfam11588
1034836004764	3-ketoacyl-(acyl-carrier-protein) reductase; Provisional; Region: fabG; PRK05565
1034836004765	classical (c) SDRs; Region: SDR_c; cd05233
1034836004766	NAD(P) binding site [chemical binding]; other site
1034836004767	active site
1034836004768	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
1034836004769	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
1034836004770	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
1034836004771	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
1034836004772	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
1034836004773	MMPL family; Region: MMPL; pfam03176
1034836004774	Predicted drug exporters of the RND superfamily [General function prediction only]; Region: COG2409
1034836004775	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1034836004776	MarR family; Region: MarR_2; pfam12802
1034836004777	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1034836004778	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1034836004779	putative substrate translocation pore; other site
1034836004780	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
1034836004781	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1034836004782	DNA-binding site [nucleotide binding]; DNA binding site
1034836004783	UTRA domain; Region: UTRA; pfam07702
1034836004784	Domain of unknown function (DUF4117); Region: DUF4117; pfam13491
1034836004785	DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell division and chromosome partitioning]; Region: FtsK; COG1674
1034836004786	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
1034836004787	Ftsk gamma domain; Region: Ftsk_gamma; pfam09397
1034836004788	YlzJ-like protein; Region: YlzJ; pfam14035
1034836004789	Clp protease; Region: CLP_protease; pfam00574
1034836004790	Caseinolytic protease (ClpP) is an ATP-dependent protease; Region: Clp_protease_like; cl15763
1034836004791	active site
1034836004792	mRNA degradation ribonucleases J1/J2 (metallo-beta-lactamase superfamily) [Translation, ribosomal structure and biogenesis; Replication, recombination and repair]; Region: COG0595
1034836004793	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
1034836004794	RNA-metabolising metallo-beta-lactamase; Region: RMMBL; pfam07521
1034836004795	Dihydrodipicolinate synthase (DHDPS); Region: DHDPS; cd00950
1034836004796	dihydrodipicolinate synthase; Region: dapA; TIGR00674
1034836004797	dimer interface [polypeptide binding]; other site
1034836004798	active site
1034836004799	catalytic residue [active]
1034836004800	aspartate kinase I; Reviewed; Region: PRK08210
1034836004801	AAK_AKi-DapG-BS: Amino Acid Kinase Superfamily (AAK), AKi-DapG; this CD includes the N-terminal catalytic aspartokinase (AK) domain of  the diaminopimelate-sensitive aspartokinase isoenzyme AKI (DapG), a monofunctional class enzyme found in Bacilli; Region: AAK_AKi-DapG-BS; cd04260
1034836004802	putative catalytic residues [active]
1034836004803	putative nucleotide binding site [chemical binding]; other site
1034836004804	putative aspartate binding site [chemical binding]; other site
1034836004805	ACT domains of the diaminopimelate-sensitive aspartokinase (AK) isoenzyme AKI; Region: ACT_AKi-DapG-BS_1; cd04914
1034836004806	ACT domains of the diaminopimelate-sensitive aspartokinase (AK) isoenzyme AKI; Region: ACT_AKi-DapG-BS_2; cd04937
1034836004807	aspartate-semialdehyde dehydrogenase; Provisional; Region: PRK14874
1034836004808	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
1034836004809	dipicolinate synthase subunit B; Reviewed; Region: spoVFB; PRK08305
1034836004810	dipicolinate synthase subunit A; Reviewed; Region: PRK08306
1034836004811	Formate/glycerate dehydrogenases, D-specific 2-hydroxy acid dehydrogenases and related dehydrogenases; Region: FDH_GDH_like; cl17240
1034836004812	NAD binding site [chemical binding]; other site
1034836004813	sporulation protein, YlmC/YmxH family; Region: spore_YlmC_YmxH; TIGR02888
1034836004814	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
1034836004815	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
1034836004816	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
1034836004817	probable sporulation protein, polysaccharide deacetylase family; Region: spore_ylxY; TIGR02873
1034836004818	Putative catalytic NodB homology domain of uncharacterized protein YlxY from Bacillus subtilis and its bacterial homologs; Region: CE4_BsYlxY_like; cd10950
1034836004819	NodB motif; other site
1034836004820	polynucleotide phosphorylase/polyadenylase; Provisional; Region: PRK11824
1034836004821	Polyribonucleotide nucleotidyltransferase, repeat 1; Region: RNase_PH_PNPase_1; cd11363
1034836004822	RNase E interface [polypeptide binding]; other site
1034836004823	trimer interface [polypeptide binding]; other site
1034836004824	Polyribonucleotide nucleotidyltransferase, RNA binding domain; Region: PNPase; pfam03726
1034836004825	Polyribonucleotide nucleotidyltransferase, repeat 2; Region: RNase_PH_PNPase_2; cd11364
1034836004826	RNase E interface [polypeptide binding]; other site
1034836004827	trimer interface [polypeptide binding]; other site
1034836004828	active site
1034836004829	Polynucleotide phosphorylase (PNPase) K homology RNA-binding domain (KH). PNPase is a polyribonucleotide nucleotidyl transferase that degrades mRNA in prokaryotes and plant chloroplasts. The C-terminal region of PNPase contains domains homologous to...; Region: PNPase_KH; cd02393
1034836004830	putative nucleic acid binding region [nucleotide binding]; other site
1034836004831	G-X-X-G motif; other site
1034836004832	S1_PNPase: Polynucleotide phosphorylase (PNPase), ), S1-like RNA-binding domain. PNPase  is a polyribonucleotide nucleotidyl transferase that degrades mRNA. It is a trimeric multidomain protein. The C-terminus contains the S1 domain which binds ssRNA; Region: S1_PNPase; cd04472
1034836004833	RNA binding site [nucleotide binding]; other site
1034836004834	domain interface; other site
1034836004835	bifunctional riboflavin kinase/FMN adenylyltransferase; Reviewed; Region: PRK05627
1034836004836	FAD synthetase, N-terminal domain of the bifunctional enzyme; Region: FAD_synthetase_N; cd02064
1034836004837	active site
1034836004838	Riboflavin kinase; Region: Flavokinase; smart00904
1034836004839	tRNA pseudouridine synthase B; Provisional; Region: truB; PRK01550
1034836004840	Pseudouridine synthase, Escherichia coli TruB like; Region: PseudoU_synth_EcTruB; cd02573
1034836004841	RNA binding site [nucleotide binding]; other site
1034836004842	active site
1034836004843	ribosome-binding factor A; Validated; Region: rbfA; PRK00521
1034836004844	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1550
1034836004845	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
1034836004846	translation initiation factor IF-2; Region: IF-2; TIGR00487
1034836004847	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
1034836004848	Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; Region: IF2_eIF5B; cd01887
1034836004849	G1 box; other site
1034836004850	putative GEF interaction site [polypeptide binding]; other site
1034836004851	GTP/Mg2+ binding site [chemical binding]; other site
1034836004852	Switch I region; other site
1034836004853	G2 box; other site
1034836004854	G3 box; other site
1034836004855	Switch II region; other site
1034836004856	G4 box; other site
1034836004857	G5 box; other site
1034836004858	This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; Region: IF2_mtIF2_II; cd03702
1034836004859	Translation-initiation factor 2; Region: IF-2; pfam11987
1034836004860	mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; Region: mtIF2_IVc; cd03692
1034836004861	Ribosomal protein L7Ae/L30e/S12e/Gadd45 family; Region: Ribosomal_L7Ae; cl00600
1034836004862	Ylxr homologs; group of conserved hypothetical bacterial proteins of unknown function; structure revealed putative RNA binding cleft; proteins are encoded by an operon that includes other proteins involved in transcription and/or translation; Region: YlxR; cd00279
1034836004863	putative RNA binding cleft [nucleotide binding]; other site
1034836004864	transcription elongation factor NusA; Provisional; Region: nusA; PRK12327
1034836004865	NusA N-terminal domain; Region: NusA_N; pfam08529
1034836004866	S1_NusA: N-utilizing substance A protein (NusA), S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. NusA is a transcription elongation factor containing an N-terminal catalytic domain and three...; Region: S1_NusA; cd04455
1034836004867	RNA binding site [nucleotide binding]; other site
1034836004868	homodimer interface [polypeptide binding]; other site
1034836004869	NusA-like KH domain; Region: KH_5; pfam13184
1034836004870	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
1034836004871	G-X-X-G motif; other site
1034836004872	ribosome maturation protein RimP; Reviewed; Region: PRK00092
1034836004873	Sm and related proteins; Region: Sm_like; cl00259
1034836004874	Bacillus subtilis YxlS-like, C-terminal domain; Region: YlxS_C; cd01734
1034836004875	putative oligomer interface [polypeptide binding]; other site
1034836004876	putative RNA binding site [nucleotide binding]; other site
1034836004877	DNA polymerase III PolC; Validated; Region: polC; PRK00448
1034836004878	DNA polymerase III polC-type N-terminus; Region: DNA_pol3_alph_N; pfam11490
1034836004879	polC_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold nucleic acid binding domain of Bacillus subtilis type C replicative DNA polymerase III alpha subunit (polC). Replication in B. subtilis and Staphylococcus aureus requires two...; Region: polC_OBF; cd04484
1034836004880	generic binding surface II; other site
1034836004881	generic binding surface I; other site
1034836004882	Polymerase and Histidinol Phosphatase domain; Region: PHP; cl17102
1034836004883	active site
1034836004884	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
1034836004885	active site
1034836004886	catalytic site [active]
1034836004887	substrate binding site [chemical binding]; other site
1034836004888	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III at PolC gene; Region: PHP_PolIIIA_POLC; cd07435
1034836004889	prolyl-tRNA synthetase; Provisional; Region: PRK09194
1034836004890	Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ProRS_core_prok; cd00779
1034836004891	dimer interface [polypeptide binding]; other site
1034836004892	motif 1; other site
1034836004893	active site
1034836004894	motif 2; other site
1034836004895	INS is an amino acid-editing domain inserted (INS) into the bacterial class II prolyl-tRNA synthetase (ProRS) however, this CD is not exclusively bacterial. It is also found at the N-terminus of the eukaryotic/archaea-like ProRS's of yeasts and...; Region: ProRS-INS; cd04334
1034836004896	putative deacylase active site [active]
1034836004897	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
1034836004898	active site
1034836004899	motif 3; other site
1034836004900	ProRS Prolyl-anticodon binding domain, short version found predominantly in bacteria. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding; Region: ProRS_anticodon_short; cd00861
1034836004901	anticodon binding site; other site
1034836004902	RIP metalloprotease RseP; Region: TIGR00054
1034836004903	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
1034836004904	active site
1034836004905	Site-2 protease (S2P) class of zinc metalloproteases (MEROPS family M50) cleaves transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of this family use proteolytic...; Region: S2P-M50; cl10020
1034836004906	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
1034836004907	protein binding site [polypeptide binding]; other site
1034836004908	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
1034836004909	putative substrate binding region [chemical binding]; other site
1034836004910	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Provisional; Region: PRK05447
1034836004911	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Region: DXP_reductoisom; pfam02670
1034836004912	1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal; Region: DXP_redisom_C; pfam08436
1034836004913	DXP reductoisomerase C-terminal domain; Region: DXPR_C; pfam13288
1034836004914	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
1034836004915	Cytidylyltransferase family; Region: CTP_transf_1; pfam01148
1034836004916	Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS); homodimers which catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl...; Region: CIS_IPPS; cd00475
1034836004917	Putative undecaprenyl diphosphate synthase; Region: Prenyltransf; pfam01255
1034836004918	catalytic residue [active]
1034836004919	putative FPP diphosphate  binding site; other site
1034836004920	putative FPP binding hydrophobic cleft; other site
1034836004921	dimer interface [polypeptide binding]; other site
1034836004922	putative IPP diphosphate binding site; other site
1034836004923	ribosome recycling factor; Reviewed; Region: frr; PRK00083
1034836004924	Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation.  Thus ribosomes are "recycled" and ready for another...; Region: RRF; cd00520
1034836004925	hinge region; other site
1034836004926	UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and...; Region: AAK_UMPK-PyrH-Ec; cd04254
1034836004927	putative nucleotide binding site [chemical binding]; other site
1034836004928	uridine monophosphate binding site [chemical binding]; other site
1034836004929	homohexameric interface [polypeptide binding]; other site
1034836004930	elongation factor Ts; Provisional; Region: tsf; PRK09377
1034836004931	UBA/TS-N domain; Region: UBA; pfam00627
1034836004932	Elongation factor TS; Region: EF_TS; pfam00889
1034836004933	Elongation factor TS; Region: EF_TS; pfam00889
1034836004934	Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425
1034836004935	rRNA interaction site [nucleotide binding]; other site
1034836004936	S8 interaction site; other site
1034836004937	putative laminin-1 binding site; other site
1034836004938	RNA polymerase sigma factor SigD; Validated; Region: PRK07670
1034836004939	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1034836004940	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
1034836004941	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1034836004942	DNA binding residues [nucleotide binding]
1034836004943	Chemotaxis protein; stimulates methylation of MCP proteins [Cell motility and secretion / Signal transduction mechanisms]; Region: CheD; COG1871
1034836004944	Chemotaxis protein CheC, inhibitor of MCP methylation [Cell motility and secretion / Signal transduction mechanisms]; Region: CheC; COG1776
1034836004945	CheC-like family; Region: CheC; pfam04509
1034836004946	CheC-like family; Region: CheC; pfam04509
1034836004947	CheW, a small regulator protein, unique to the chemotaxis signalling in prokaryotes and archea. CheW interacts with the histidine kinase CheA, most likely with the related regulatory domain of CheA. CheW is proposed to form signalling arrays together...; Region: CheW; cd00732
1034836004948	putative CheA interaction surface; other site
1034836004949	Chemotaxis protein histidine kinase and related kinases [Cell motility and secretion / Signal transduction mechanisms]; Region: CheA; COG0643
1034836004950	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
1034836004951	putative binding surface; other site
1034836004952	active site
1034836004953	P2 response regulator binding domain; Region: P2; pfam07194
1034836004954	Signal transducing histidine kinase, homodimeric domain; Region: H-kinase_dim; pfam02895
1034836004955	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1034836004956	ATP binding site [chemical binding]; other site
1034836004957	Mg2+ binding site [ion binding]; other site
1034836004958	G-X-G motif; other site
1034836004959	CheA regulatory domain; CheA is a histidine protein kinase present in bacteria and archea. Activated by the chemotaxis receptor a histidine phosphoryl group from CheA is passed directly to an aspartate in the response regulator CheY. This signalling...; Region: CheA_reg; cd00731
1034836004960	chemotaxis-specific methylesterase; Provisional; Region: PRK00742
1034836004961	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1034836004962	active site
1034836004963	phosphorylation site [posttranslational modification]
1034836004964	intermolecular recognition site; other site
1034836004965	dimerization interface [polypeptide binding]; other site
1034836004966	CheB methylesterase; Region: CheB_methylest; pfam01339
1034836004967	Antiactivator of flagellar biosynthesis FleN, an ATPase [Cell motility]; Region: flhG; COG0455
1034836004968	FleN is a member of the Fer4_NifH superfamily. It shares the common function as an ATPase, with the ATP-binding domain at the N-terminus. In Pseudomonas aeruginosa, FleN gene is involved in regulating the number of flagella and chemotactic motility by...; Region: FleN-like; cd02038
1034836004969	P-loop; other site
1034836004970	FleN is a member of the Fer4_NifH superfamily. It shares the common function as an ATPase, with the ATP-binding domain at the N-terminus. In Pseudomonas aeruginosa, FleN gene is involved in regulating the number of flagella and chemotactic motility by...; Region: FleN-like; cd02038
1034836004971	flagellar biosynthesis regulator FlhF; Validated; Region: flhF; PRK05703
1034836004972	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
1034836004973	flagellar biosynthesis protein FlhA; Validated; Region: flhA; PRK06012
1034836004974	FHIPEP family; Region: FHIPEP; pfam00771
1034836004975	flagellar biosynthesis protein FlhB; Reviewed; Region: flhB; PRK05702
1034836004976	Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB [Function unknown]; Region: COG2257
1034836004977	flagellar biosynthesis protein FliR; Reviewed; Region: fliR; PRK05701
1034836004978	flagellar biosynthesis protein FliQ; Validated; Region: fliQ; PRK05700
1034836004979	flagellar biosynthesis protein FliP; Reviewed; Region: fliP; PRK05699
1034836004980	flagella biosynthesis protein FliZ; Provisional; Region: PRK13415
1034836004981	Response regulator receiver domain; Region: Response_reg; pfam00072
1034836004982	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1034836004983	active site
1034836004984	phosphorylation site [posttranslational modification]
1034836004985	intermolecular recognition site; other site
1034836004986	dimerization interface [polypeptide binding]; other site
1034836004987	flagellar motor switch protein; Validated; Region: PRK08119
1034836004988	CheC-like family; Region: CheC; pfam04509
1034836004989	CheC-like family; Region: CheC; pfam04509
1034836004990	flagellar motor switch protein FliN; Region: fliN; TIGR02480
1034836004991	flagellar motor switch protein FliM; Validated; Region: fliM; PRK06666
1034836004992	Surface presentation of antigens (SPOA); Region: SpoA; pfam01052
1034836004993	Flagellar basal body-associated protein [Cell motility and secretion]; Region: FliL; COG1580
1034836004994	flagellar basal body-associated protein FliL; Reviewed; Region: fliL; PRK07718
1034836004995	Flagellar protein (FlbD); Region: FlbD; pfam06289
1034836004996	flagellar basal body rod protein FlgG; Provisional; Region: flgG; PRK12636
1034836004997	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
1034836004998	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1034836004999	flagellar basal body rod modification protein; Provisional; Region: flgD; PRK09618
1034836005000	Flagellar hook capping protein - N-terminal region; Region: FlgD; pfam03963
1034836005001	Flagellar hook-length control protein FliK; Region: Flg_hook; pfam02120
1034836005002	Uncharacterized conserved protein [Function unknown]; Region: COG3334
1034836005003	Flagellar biosynthesis chaperone [Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones]; Region: FliJ; COG2882
1034836005004	flagellar biosynthesis chaperone; Validated; Region: fliJ; PRK07720
1034836005005	flagellum-specific ATP synthase; Validated; Region: fliI; PRK07721
1034836005006	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
1034836005007	Flagellum-specific ATPase/type III secretory pathway virulence-related protein. This group of ATPases are responsible for the export of flagellum and virulence-related proteins. The bacterial flagellar motor is similar to the F0F1-ATPase, in that they...; Region: ATPase_flagellum-secretory_path_III; cd01136
1034836005008	Walker A motif/ATP binding site; other site
1034836005009	Walker B motif; other site
1034836005010	flagellar assembly protein FliH; Region: FliH_bacil; TIGR03825
1034836005011	Flagellar assembly protein FliH; Region: FliH; pfam02108
1034836005012	flagellar motor switch protein FliG; Region: fliG; TIGR00207
1034836005013	MgtE intracellular N domain; Region: MgtE_N; smart00924
1034836005014	FliG C-terminal domain; Region: FliG_C; pfam01706
1034836005015	flagellar basal-body M-ring protein/flagellar hook-basal body protein (fliF); Region: fliF; TIGR00206
1034836005016	Secretory protein of YscJ/FliF family; Region: YscJ_FliF; pfam01514
1034836005017	Flagellar M-ring protein C-terminal; Region: YscJ_FliF_C; pfam08345
1034836005018	flagellar hook-basal body protein FliE; Provisional; Region: fliE; PRK12728
1034836005019	flagellar basal body rod protein FlgC; Reviewed; Region: flgC; PRK05681
1034836005020	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
1034836005021	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1034836005022	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK05680
1034836005023	transcriptional repressor CodY; Validated; Region: PRK04158
1034836005024	CodY GAF-like domain; Region: CodY; pfam06018
1034836005025	CodY helix-turn-helix domain; Region: HTH_CodY; pfam08222
1034836005026	ATP-dependent protease ATP-binding subunit HslU; Provisional; Region: hslU; PRK05201
1034836005027	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1034836005028	Walker A motif; other site
1034836005029	ATP binding site [chemical binding]; other site
1034836005030	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
1034836005031	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
1034836005032	Protease HslV and the ATPase/chaperone HslU are part of an ATP-dependent proteolytic system that is the prokaryotic homolog of the proteasome. HslV is a dimer of hexamers (a dodecamer) that forms a central proteolytic chamber with active sites on the...; Region: protease_HslV; cd01913
1034836005033	active site
1034836005034	HslU subunit interaction site [polypeptide binding]; other site
1034836005035	Site-specific recombinase XerD [DNA replication, recombination, and repair]; Region: XerD; COG4974
1034836005036	XerD and XerC integrases, DNA breaking-rejoining enzymes, N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination...; Region: INT_XerDC; cd00798
1034836005037	active site
1034836005038	Int/Topo IB signature motif; other site
1034836005039	tRNA (uracil-5-)-methyltransferase Gid; Reviewed; Region: PRK05335
1034836005040	Glucose inhibited division protein A; Region: GIDA; pfam01134
1034836005041	DNA topoisomerase I; Validated; Region: PRK05582
1034836005042	TOPRIM_TopoIA_TopoI: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to Escherichia coli DNA topoisomerase I.   Type IA DNA topoisomerases remove (relax) negative supercoils in the...; Region: TOPRIM_TopoIA_TopoI; cd03363
1034836005043	active site
1034836005044	interdomain interaction site; other site
1034836005045	putative metal-binding site [ion binding]; other site
1034836005046	nucleotide binding site [chemical binding]; other site
1034836005047	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
1034836005048	domain I; other site
1034836005049	DNA binding groove [nucleotide binding]
1034836005050	phosphate binding site [ion binding]; other site
1034836005051	domain II; other site
1034836005052	domain III; other site
1034836005053	nucleotide binding site [chemical binding]; other site
1034836005054	catalytic site [active]
1034836005055	domain IV; other site
1034836005056	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1034836005057	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1034836005058	DNA protecting protein DprA; Region: dprA; TIGR00732
1034836005059	DNA recombination-mediator protein A; Region: DNA_processg_A; pfam02481
1034836005060	succinyl-CoA synthetase subunit alpha; Validated; Region: PRK05678
1034836005061	CoA binding domain; Region: CoA_binding; smart00881
1034836005062	CoA-ligase; Region: Ligase_CoA; pfam00549
1034836005063	succinyl-CoA synthetase subunit beta; Provisional; Region: sucC; PRK00696
1034836005064	ATP-grasp domain; Region: ATP-grasp_2; pfam08442
1034836005065	CoA-ligase; Region: Ligase_CoA; pfam00549
1034836005066	Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB [Function unknown]; Region: COG2257
1034836005067	bacterial Ribonuclease HII-like; Region: RNase_HII_bacteria_HII_like; cd07182
1034836005068	RNA/DNA hybrid binding site [nucleotide binding]; other site
1034836005069	active site
1034836005070	GTPase YlqF; Reviewed; Region: rbgA; PRK09563
1034836005071	Circularly permuted YlqF GTPase; Region: YlqF; cd01856
1034836005072	GTP/Mg2+ binding site [chemical binding]; other site
1034836005073	G4 box; other site
1034836005074	G5 box; other site
1034836005075	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cd00882
1034836005076	G1 box; other site
1034836005077	G1 box; other site
1034836005078	GTP/Mg2+ binding site [chemical binding]; other site
1034836005079	Switch I region; other site
1034836005080	G2 box; other site
1034836005081	G2 box; other site
1034836005082	G3 box; other site
1034836005083	G3 box; other site
1034836005084	Switch II region; other site
1034836005085	Switch II region; other site
1034836005086	tRNA (guanine-N(1)-)-methyltransferase; Reviewed; Region: trmD; PRK00026
1034836005087	16S rRNA-processing protein RimM; Provisional; Region: rimM; PRK00122
1034836005088	RimM N-terminal domain; Region: RimM; pfam01782
1034836005089	PRC-barrel domain; Region: PRC; pfam05239
1034836005090	Protein of unknown function (DUF2869); Region: DUF2869; pfam11068
1034836005091	Predicted RNA-binding protein (contains KH domain) [General function prediction only]; Region: COG1837
1034836005092	KH domain; Region: KH_4; pfam13083
1034836005093	30S ribosomal protein S16; Reviewed; Region: rpsP; PRK00040
1034836005094	signal recognition particle protein; Provisional; Region: PRK10867
1034836005095	SRP54-type protein, helical bundle domain; Region: SRP54_N; smart00963
1034836005096	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
1034836005097	P loop; other site
1034836005098	GTP binding site [chemical binding]; other site
1034836005099	Signal peptide binding domain; Region: SRP_SPB; pfam02978
1034836005100	putative DNA-binding protein; Validated; Region: PRK00118
1034836005101	Putative helix-turn-helix protein, YlxM / p13 like; Region: UPF0122; pfam04297
1034836005102	signal recognition particle-docking protein FtsY; Provisional; Region: PRK10416
1034836005103	SRP54-type protein, helical bundle domain; Region: SRP54_N; pfam02881
1034836005104	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
1034836005105	GTP binding site [chemical binding]; other site
1034836005106	chromosome segregation protein SMC, common bacterial type; Region: SMC_prok_B; TIGR02168
1034836005107	ATP-binding cassette domain of barmotin, a member of the SMC protein family; Region: ABC_SMC_barmotin; cd03278
1034836005108	Walker A/P-loop; other site
1034836005109	ATP binding site [chemical binding]; other site
1034836005110	Q-loop/lid; other site
1034836005111	SMC proteins Flexible Hinge Domain; Region: SMC_hinge; smart00968
1034836005112	ATP-binding cassette domain of barmotin, a member of the SMC protein family; Region: ABC_SMC_barmotin; cd03278
1034836005113	ABC transporter signature motif; other site
1034836005114	Walker B; other site
1034836005115	D-loop; other site
1034836005116	H-loop/switch region; other site
1034836005117	ribonuclease III, bacterial; Region: RNaseIII; TIGR02191
1034836005118	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
1034836005119	dimerization interface [polypeptide binding]; other site
1034836005120	active site
1034836005121	metal binding site [ion binding]; metal-binding site
1034836005122	Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048
1034836005123	dsRNA binding site [nucleotide binding]; other site
1034836005124	acyl carrier protein; Provisional; Region: acpP; PRK00982
1034836005125	beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs; Region: BKR_SDR_c; cd05333
1034836005126	3-oxoacyl-(acyl-carrier-protein) reductase; Region: 3oxo_ACP_reduc; TIGR01830
1034836005127	NAD(P) binding site [chemical binding]; other site
1034836005128	homotetramer interface [polypeptide binding]; other site
1034836005129	homodimer interface [polypeptide binding]; other site
1034836005130	active site
1034836005131	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
1034836005132	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
1034836005133	putative phosphate acyltransferase; Provisional; Region: PRK05331
1034836005134	fatty acid biosynthesis transcriptional regulator; Provisional; Region: PRK04424
1034836005135	HGG motif-containing thioesterase, possibly involved in aromatic compounds catabolism [Secondary metabolites biosynthesis,    transport, and catabolism]; Region: PaaI; COG2050
1034836005136	ATP-dependent DNA helicase RecG; Provisional; Region: PRK10917
1034836005137	RecG_wedge_OBF: A subfamily of OB folds corresponding to the OB fold found in the N-terminal (wedge) domain of Escherichia coli RecG. RecG is a branched-DNA-specific helicase, which catalyzes the interconversion of a DNA replication fork to a...; Region: RecG_wedge_OBF; cd04488
1034836005138	generic binding surface II; other site
1034836005139	ssDNA binding site; other site
1034836005140	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1034836005141	ATP binding site [chemical binding]; other site
1034836005142	putative Mg++ binding site [ion binding]; other site
1034836005143	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1034836005144	nucleotide binding region [chemical binding]; other site
1034836005145	ATP-binding site [chemical binding]; other site
1034836005146	Serine dehydratase alpha chain; Region: SDH_alpha; cl12120
1034836005147	L-serine deaminase [Amino acid transport and metabolism]; Region: SdaA; COG1760
1034836005148	L-serine dehydratase, iron-sulfur-dependent, beta subunit; Region: sda_beta; TIGR00719
1034836005149	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
1034836005150	C-terminal ACT domain of the L-serine dehydratase (LSD), iron-sulfur-dependent, beta subunit; Region: ACT_LSD; cd04903
1034836005151	putative L-serine binding site [chemical binding]; other site
1034836005152	DAK2 domain fusion protein YloV; Region: YloV; TIGR03599
1034836005153	DAK2 domain; Region: Dak2; pfam02734
1034836005154	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1302
1034836005155	50S ribosomal protein L28; Reviewed; Region: rpmB; PRK00359
1034836005156	stage V sporulation protein M; Provisional; Region: spoVM; PRK14741
1034836005157	Thiamine pyrophosphokinase; Region: TPK; cd07995
1034836005158	thiamine pyrophosphokinase; Region: thi_PPkinase; TIGR01378
1034836005159	active site
1034836005160	dimerization interface [polypeptide binding]; other site
1034836005161	thiamine binding site [chemical binding]; other site
1034836005162	Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]; Region: Rpe; COG0036
1034836005163	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
1034836005164	substrate binding site [chemical binding]; other site
1034836005165	hexamer interface [polypeptide binding]; other site
1034836005166	metal binding site [ion binding]; metal-binding site
1034836005167	GTPase RsgA; Reviewed; Region: PRK00098
1034836005168	S1_YloQ_GTPase: YloQ GTase family (also known as YjeQ and CpgA), S1-like RNA-binding domain. Proteins in the YloQ GTase family bind the ribosome and have GTPase activity. The precise role of this family is unknown. The protein structure is composed of...; Region: S1_YloQ_GTPase; cd04466
1034836005169	RNA binding site [nucleotide binding]; other site
1034836005170	homodimer interface [polypeptide binding]; other site
1034836005171	Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; Region: YjeQ_EngC; cd01854
1034836005172	GTPase/Zn-binding domain interface [polypeptide binding]; other site
1034836005173	GTP/Mg2+ binding site [chemical binding]; other site
1034836005174	G4 box; other site
1034836005175	G5 box; other site
1034836005176	G1 box; other site
1034836005177	Switch I region; other site
1034836005178	G2 box; other site
1034836005179	G3 box; other site
1034836005180	Switch II region; other site
1034836005181	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
1034836005182	Catalytic domain of Protein Kinases; Region: PKc; cd00180
1034836005183	active site
1034836005184	ATP binding site [chemical binding]; other site
1034836005185	substrate binding site [chemical binding]; other site
1034836005186	activation loop (A-loop); other site
1034836005187	Protein Kinases, catalytic domain; Region: PKc_like; cl09925
1034836005188	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2815
1034836005189	PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577
1034836005190	PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577
1034836005191	PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577
1034836005192	Protein phosphatase 2C; Region: PP2C; pfam00481
1034836005193	Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence...; Region: PP2Cc; cd00143
1034836005194	active site
1034836005195	ribosomal RNA large subunit methyltransferase N; Provisional; Region: PRK14455
1034836005196	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1034836005197	FeS/SAM binding site; other site
1034836005198	16S rRNA methyltransferase B; Provisional; Region: PRK14902
1034836005199	N-terminal RNA binding domain of the methyltransferase Sun. The rRNA-specific 5-methylcytidine transferase Sun, also known as RrmB or Fmu shares the RNA-binding non-catalytic domain with the transcription termination factor NusB. The precise biological...; Region: Methyltransferase_Sun; cd00620
1034836005200	putative RNA binding site [nucleotide binding]; other site
1034836005201	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1034836005202	S-adenosylmethionine binding site [chemical binding]; other site
1034836005203	methionyl-tRNA formyltransferase; Reviewed; Region: fmt; PRK00005
1034836005204	Methionyl-tRNA formyltransferase, N-terminal hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N; cd08646
1034836005205	putative active site [active]
1034836005206	substrate binding site [chemical binding]; other site
1034836005207	putative cosubstrate binding site; other site
1034836005208	catalytic site [active]
1034836005209	C-terminal domain of Formyltransferase and other enzymes; Region: Met_tRNA_FMT_C; cd08704
1034836005210	substrate binding site [chemical binding]; other site
1034836005211	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
1034836005212	active site
1034836005213	catalytic residues [active]
1034836005214	metal binding site [ion binding]; metal-binding site
1034836005215	Primosomal protein N' (replication factor Y) - superfamily II helicase [DNA replication, recombination, and repair]; Region: PriA; COG1198
1034836005216	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1034836005217	ATP binding site [chemical binding]; other site
1034836005218	putative Mg++ binding site [ion binding]; other site
1034836005219	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1034836005220	nucleotide binding region [chemical binding]; other site
1034836005221	ATP-binding site [chemical binding]; other site
1034836005222	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated; Region: PRK05579
1034836005223	Flavoprotein; Region: Flavoprotein; pfam02441
1034836005224	DNA / pantothenate metabolism flavoprotein; Region: DFP; pfam04127
1034836005225	DNA-directed RNA polymerase, omega subunit; Region: rpoZ; TIGR00690
1034836005226	Guanylate kinase [Nucleotide transport and metabolism]; Region: Gmk; COG0194
1034836005227	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
1034836005228	catalytic site [active]
1034836005229	G-X2-G-X-G-K; other site
1034836005230	hypothetical protein; Provisional; Region: PRK04323
1034836005231	TIGR00255 family protein; Region: TIGR00255
1034836005232	YicC-like family, N-terminal region; Region: YicC_N; pfam03755
1034836005233	Domain of unknown function (DUF1732); Region: DUF1732; pfam08340
1034836005234	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: MgtA; COG0474
1034836005235	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; smart00831
1034836005236	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1034836005237	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
1034836005238	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1034836005239	motif II; other site
1034836005240	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
1034836005241	Fibronectin-binding protein A N-terminus (FbpA); Region: FbpA; pfam05833
1034836005242	Domain of unknown function (DUF814); Region: DUF814; pfam05670
1034836005243	cytoplasmic alpha-amylase; Reviewed; Region: PRK09441
1034836005244	Alpha amylase catalytic domain found in bacterial and fungal Alpha amylases (also called 1,4-alpha-D-glucan-4-glucanohydrolase); Region: AmyAc_bac_fung_AmyA; cd11318
1034836005245	active site
1034836005246	Na/Ca binding site [ion binding]; other site
1034836005247	catalytic site [active]
1034836005248	Domain of unknown function (DUF1939); Region: DUF1939; pfam09154
1034836005249	Putative NAD(P)-binding; Region: NAD_binding_7; pfam13241
1034836005250	Sirohydrochlorin ferrochelatase [Inorganic ion transport and metabolism]; Region: COG2138
1034836005251	Sirohydrochlorin cobalt chelatase (CbiX) and sirohydrochlorin iron chelatase (SirB), N-terminal domain. SirB catalyzes the ferro-chelation of sirohydrochlorin to siroheme, the prosthetic group of sulfite and nitrite reductases. CbiX is a cobaltochelatase; Region: CbiX_SirB_N; cd03416
1034836005252	putative active site [active]
1034836005253	Sirohydrochlorin cobalt chelatase (CbiX) and sirohydrochlorin iron chelatase (SirB), C-terminal domain. SirB catalyzes the ferro-chelation of sirohydrochlorin to siroheme, the prosthetic group of sulfite and nitrite reductases. CbiX is a cobaltochelatase; Region: CbiX_SirB_C; cd03414
1034836005254	putative active site [active]
1034836005255	Uroporphyrin-III C-methyltransferase (S-Adenosyl-L-methionine:uroporphyrinogen III methyltransferase, SUMT); Region: SUMT; cd11642
1034836005256	diphthine synthase; Region: dph5; TIGR00522
1034836005257	active site
1034836005258	SAM binding site [chemical binding]; other site
1034836005259	homodimer interface [polypeptide binding]; other site
1034836005260	AAA domain; Region: AAA_33; pfam13671
1034836005261	Adenosine 5'-phosphosulfate kinase (APSK) catalyzes the phosphorylation of adenosine 5'-phosphosulfate to form 3'-phosphoadenosine 5'-phosphosulfate (PAPS). The end-product PAPS is a biologically "activated" sulfate form...; Region: APSK; cd02027
1034836005262	ligand-binding site [chemical binding]; other site
1034836005263	sulfate adenylyltransferase; Reviewed; Region: sat; PRK04149
1034836005264	ATP-sulfurylase; Region: ATPS; cd00517
1034836005265	active site
1034836005266	HXXH motif; other site
1034836005267	flexible loop; other site
1034836005268	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
1034836005269	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes [Amino acid transport and metabolism / Coenzyme metabolism]; Region: CysH; COG0175
1034836005270	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
1034836005271	Active Sites [active]
1034836005272	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1034836005273	active site
1034836005274	Orotidine 5'-phosphate decarboxylase (ODCase) is a dimeric enzyme that decarboxylates orotidine 5'-monophosphate (OMP) to form uridine 5'-phosphate (UMP), an essential step in the pyrimidine biosynthetic pathway. In mammals, UMP synthase...; Region: OMP_decarboxylase_like; cd04725
1034836005275	active site
1034836005276	dimer interface [polypeptide binding]; other site
1034836005277	dihydroorotate dehydrogenase (subfamily 1) family protein; Region: pyrD_sub1_fam; TIGR01037
1034836005278	Dihydroorotate dehydrogenase (DHOD) class 1B FMN-binding domain. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine...; Region: DHOD_1B_like; cd04740
1034836005279	heterodimer interface [polypeptide binding]; other site
1034836005280	active site
1034836005281	FMN binding site [chemical binding]; other site
1034836005282	homodimer interface [polypeptide binding]; other site
1034836005283	substrate binding site [chemical binding]; other site
1034836005284	dihydroorotate dehydrogenase electron transfer subunit; Reviewed; Region: PRK00054
1034836005285	FAD/NAD binding domain in the electron transfer subunit of dihydroorotate dehydrogenase. Dihydroorotate dehydrogenases (DHODs) catalyze the only redox reaction in pyrimidine de novo biosynthesis. They catalyze the oxidation of (S)-dihydroorotate to...; Region: DHOD_e_trans; cd06218
1034836005286	FAD binding pocket [chemical binding]; other site
1034836005287	FAD binding motif [chemical binding]; other site
1034836005288	phosphate binding motif [ion binding]; other site
1034836005289	beta-alpha-beta structure motif; other site
1034836005290	NAD binding pocket [chemical binding]; other site
1034836005291	Iron coordination center [ion binding]; other site
1034836005292	carbamoyl phosphate synthase large subunit; Reviewed; Region: carB; PRK05294
1034836005293	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1034836005294	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
1034836005295	Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; pfam02787
1034836005296	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1034836005297	ATP-grasp domain; Region: ATP-grasp_4; cl17255
1034836005298	Methylglyoxal synthase-like domain from type II glutamine-dependent carbamoyl phosphate synthetase (CSP). CSP, a CarA and CarB heterodimer, catalyzes the production of carbamoyl phosphate which is subsequently employed in the metabolic pathways...; Region: MGS_CPS_II; cd01424
1034836005299	IMP binding site; other site
1034836005300	dimer interface [polypeptide binding]; other site
1034836005301	interdomain contacts; other site
1034836005302	partial ornithine binding site; other site
1034836005303	carbamoyl phosphate synthase small subunit; Reviewed; Region: PRK12564
1034836005304	Carbamoyl-phosphate synthase small chain, CPSase domain; Region: CPSase_sm_chain; smart01097
1034836005305	Small chain of the glutamine-dependent form of carbamoyl phosphate synthase, CPSase II; Region: GATase1_CPSase; cd01744
1034836005306	catalytic site [active]
1034836005307	subunit interface [polypeptide binding]; other site
1034836005308	dihydroorotase; Validated; Region: pyrC; PRK09357
1034836005309	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1034836005310	Dihydroorotase (DHOase), subgroup IIa; DHOases catalyze the reversible interconversion of carbamoyl aspartate to dihydroorotate, a key reaction in pyrimidine biosynthesis. This subgroup also contains proteins that lack the active site, like unc-33, a C; Region: DHOase_IIa; cd01317
1034836005311	active site
1034836005312	aspartate carbamoyltransferase catalytic subunit; Provisional; Region: pyrB; PRK00856
1034836005313	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
1034836005314	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
1034836005315	uracil-xanthine permease; Region: ncs2; TIGR00801
1034836005316	Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase [Nucleotide transport and metabolism]; Region: PyrR; COG2065
1034836005317	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1034836005318	active site
1034836005319	pseudouridine synthase, RluA family; Region: rluA_subfam; TIGR00005
1034836005320	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1034836005321	RNA binding surface [nucleotide binding]; other site
1034836005322	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1034836005323	active site
1034836005324	lipoprotein signal peptidase; Reviewed; Region: lspA; PRK00376
1034836005325	DnaK suppressor protein [Signal transduction mechanisms]; Region: DksA; COG1734
1034836005326	isoleucyl-tRNA synthetase; Reviewed; Region: ileS; PRK05743
1034836005327	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
1034836005328	HIGH motif; other site
1034836005329	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
1034836005330	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
1034836005331	active site
1034836005332	KMSKS motif; other site
1034836005333	Anticodon-binding domain of bacterial and eukaryotic mitochondrial isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_BEm; cd07960
1034836005334	tRNA binding surface [nucleotide binding]; other site
1034836005335	anticodon binding site; other site
1034836005336	DivIVA protein; Region: DivIVA; pfam05103
1034836005337	DivIVA domain; Region: DivI1A_domain; TIGR03544
1034836005338	Uncharacterized conserved protein, contains S4-like domain [Function unknown]; Region: COG2302
1034836005339	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1034836005340	RNA binding surface [nucleotide binding]; other site
1034836005341	YGGT family; Region: YGGT; pfam02325
1034836005342	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1799
1034836005343	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, YBL036c-like proteins; Region: PLPDE_III_YBL036c_like; cd00635
1034836005344	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1034836005345	catalytic residue [active]
1034836005346	Multicopper polyphenol oxidase (laccase) [Secondary metabolites biosynthesis, transport and catabolism]; Region: yfiH; COG1496
1034836005347	Multi-copper polyphenol oxidoreductase laccase; Region: Cu-oxidase_4; pfam02578
1034836005348	sporulation protein, YlmC/YmxH family; Region: spore_YlmC_YmxH; TIGR02888
1034836005349	acetylornithine deacetylase; Validated; Region: PRK08596
1034836005350	Zinc peptidases M18, M20, M28, and M42; Region: Zinc_peptidase_like; cl14876
1034836005351	metal binding site [ion binding]; metal-binding site
1034836005352	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
1034836005353	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
1034836005354	Walker A/P-loop; other site
1034836005355	ATP binding site [chemical binding]; other site
1034836005356	Q-loop/lid; other site
1034836005357	ABC transporter signature motif; other site
1034836005358	Walker B; other site
1034836005359	D-loop; other site
1034836005360	H-loop/switch region; other site
1034836005361	sporulation sigma factor SigG; Reviewed; Region: PRK08215
1034836005362	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1034836005363	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
1034836005364	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1034836005365	DNA binding residues [nucleotide binding]
1034836005366	sporulation sigma factor SigE; Reviewed; Region: PRK08301
1034836005367	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1034836005368	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1034836005369	DNA binding residues [nucleotide binding]
1034836005370	Sporulation factor SpoIIGA; Region: Peptidase_U4; pfam03419
1034836005371	sigma-E processing peptidase SpoIIGA; Region: spore_II_GA; TIGR02854
1034836005372	Peptidase inhibitor I9; Region: Inhibitor_I9; pfam05922
1034836005373	Subtilisin-like serine proteases [Posttranslational modification, protein turnover, chaperones]; Region: AprE; COG1404
1034836005374	Peptidase S8 family domain in BacillopeptidaseF-like proteins; Region: Peptidases_S8_BacillopeptidaseF-like; cd07481
1034836005375	active site
1034836005376	catalytic triad [active]
1034836005377	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4412
1034836005378	Immune inhibitor A peptidase M6; Region: Peptidase_M6; cl11525
1034836005379	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1034836005380	Cna protein B-type domain; Region: Cna_B_2; pfam13715
1034836005381	Cadherin-like beta sandwich domain; Region: Cadherin-like; pfam12733
1034836005382	cell division protein FtsZ; Validated; Region: PRK09330
1034836005383	FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes.  FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at...; Region: FtsZ_type1; cd02201
1034836005384	nucleotide binding site [chemical binding]; other site
1034836005385	SulA interaction site; other site
1034836005386	cell division protein FtsA; Region: ftsA; TIGR01174
1034836005387	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1034836005388	nucleotide binding site [chemical binding]; other site
1034836005389	Cell division protein FtsA; Region: FtsA; pfam14450
1034836005390	Cell division septal protein [Cell envelope biogenesis, outer membrane]; Region: FtsQ; COG1589
1034836005391	POTRA domain, FtsQ-type; Region: POTRA_1; pfam08478
1034836005392	Cell division protein FtsQ; Region: FtsQ; pfam03799
1034836005393	UDP-N-acetylenolpyruvoylglucosamine reductase; Provisional; Region: murB; PRK13905
1034836005394	FAD binding domain; Region: FAD_binding_4; pfam01565
1034836005395	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873
1034836005396	undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional; Region: murG; PRK00726
1034836005397	MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide...; Region: GT1_MurG; cd03785
1034836005398	active site
1034836005399	homodimer interface [polypeptide binding]; other site
1034836005400	Cell cycle protein; Region: FTSW_RODA_SPOVE; cl00511
1034836005401	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional; Region: murD; PRK02472
1034836005402	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1034836005403	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1034836005404	phospho-N-acetylmuramoyl-pentapeptide-transferase; Region: mraY; TIGR00445
1034836005405	Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of...; Region: GT_MraY; cd06852
1034836005406	Mg++ binding site [ion binding]; other site
1034836005407	putative catalytic motif [active]
1034836005408	putative substrate binding site [chemical binding]; other site
1034836005409	UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Provisional; Region: murE; PRK00139
1034836005410	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1034836005411	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1034836005412	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1034836005413	stage V sporulation protein D; Region: spoVD_pbp; TIGR02214
1034836005414	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
1034836005415	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
1034836005416	PASTA domain. This domain is found at the C-termini of several Penicillin-binding proteins (PBPs) and bacterial serine/threonine kinases. It is a small globular fold consisting of 3 beta-sheets and an alpha-helix. The name PASTA is derived from PBP and...; Region: PASTA; cd06573
1034836005417	Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane]; Region: FtsI; COG0768
1034836005418	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
1034836005419	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
1034836005420	PASTA domain of PBP2x-like proteins, first repeat. Penicillin-binding proteins (PBPs) are the major targets for beta-lactam antibiotics, like penicillins and cephalosporins. Beta-lactam antibiotics specifically inhibit transpeptidase activity by...; Region: PASTA_Pbp2x-like_1; cd06576
1034836005421	PASTA domain of PBP2x-like proteins, second repeat. Penicillin-binding proteins (PBPs) are the major targets for beta-lactam antibiotics, like penicillins and cephalosporins. Beta-lactam antibiotics specifically inhibit transpeptidase activity by...; Region: PASTA_Pbp2x-like_2; cd06575
1034836005422	Protein required for the initiation of cell division [Cell division and chromosome partitioning]; Region: FtsL; COG4839
1034836005423	MraW methylase family; Region: Methyltransf_5; pfam01795
1034836005424	16S rRNA m(4)C1402 methyltranserfase; Provisional; Region: PRK00050
1034836005425	mraZ protein; Region: TIGR00242
1034836005426	MraZ protein; Region: MraZ; pfam02381
1034836005427	MraZ protein; Region: MraZ; pfam02381
1034836005428	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4365
1034836005429	Uncharacterized protein conserved in bacteria (DUF2317); Region: DUF2317; pfam10079
1034836005430	2-dehydropantoate 2-reductase; Reviewed; Region: PRK06522
1034836005431	Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558
1034836005432	Ketopantoate reductase PanE/ApbA C terminal; Region: ApbA_C; pfam08546
1034836005433	hypothetical protein; Provisional; Region: PRK13688
1034836005434	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1034836005435	Coenzyme A binding pocket [chemical binding]; other site
1034836005436	putative spore coat protein regulator protein YlbO; Provisional; Region: PRK13923
1034836005437	transcription factor, RsfA family; Region: DNA_bind_RsfA; TIGR02894
1034836005438	50S ribosomal protein L32; Reviewed; Region: rpmF; PRK12286
1034836005439	Predicted metal-binding, possibly nucleic acid-binding protein [General function prediction only]; Region: COG1399
1034836005440	hypothetical protein; Provisional; Region: PRK13670
1034836005441	HIGH Nucleotidyl Transferase; Region: HIGH_NTase1; pfam05636
1034836005442	Predicted secreted protein containing a PDZ domain [Signal transduction mechanisms]; Region: SdrC; COG3480
1034836005443	PDZ domain of ATP-dependent LON serine proteases. Most PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated. In this bacterial subfamily of protease-associated PDZ...; Region: PDZ_LON_protease; cd00986
1034836005444	protein binding site [polypeptide binding]; other site
1034836005445	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
1034836005446	Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; Region: RssA; COG1752
1034836005447	Bacterial patatin-like phospholipase domain containing protein 6; Region: Pat_NTE_like_bacteria; cd07228
1034836005448	active site
1034836005449	nucleophile elbow; other site
1034836005450	sporulation integral membrane protein YlbJ; Region: spore_ylbJ; TIGR02871
1034836005451	Nucleoside recognition; Region: Gate; pfam07670
1034836005452	Nucleoside recognition; Region: Gate; pfam07670
1034836005453	phosphopantetheine adenylyltransferase; Provisional; Region: coaD; PRK00168
1034836005454	Phosphopantetheine adenylyltransferase; Region: PPAT; cd02163
1034836005455	active site
1034836005456	(T/H)XGH motif; other site
1034836005457	N6-adenine-specific methylase [DNA replication, recombination, and repair]; Region: COG0742
1034836005458	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1034836005459	S-adenosylmethionine binding site [chemical binding]; other site
1034836005460	hypothetical protein; Provisional; Region: PRK02886
1034836005461	Regulatory protein involved in competence development and sporulation [Replication, recombination and repair;    Signal transduction mechanisms]; Region: COG3679
1034836005462	YlbE-like protein; Region: YlbE; pfam14003
1034836005463	Putative coat protein; Region: YlbD_coat; pfam14071
1034836005464	Uncharacterized protein with SCP/PR1 domains [Function unknown]; Region: COG2340
1034836005465	SCP_bacterial: SCP-like extracellular protein domain, as found in bacteria and archaea. The wider family of SCP containing proteins includes plant pathogenesis-related protein 1 (PR-1), CRISPs, mammalian cysteine-rich secretory proteins, and allergen 5...; Region: SCP_bacterial; cd05379
1034836005466	FOG: CBS domain [General function prediction only]; Region: COG0517
1034836005467	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair_9; cd04622
1034836005468	YugN-like family; Region: YugN; pfam08868
1034836005469	Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG); Region: Caa3_CtaG; cl09173
1034836005470	cytochrome c oxidase, subunit IVB; Region: CoxD_Bacillus; TIGR02908
1034836005471	Ubiquinol oxidase subunit III subfamily. Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane.  It catalyzes the reduction of O2 and simultaneously...; Region: Ubiquinol_oxidase_III; cd02863
1034836005472	Subunit I/III interface [polypeptide binding]; other site
1034836005473	Subunit III/IV interface [polypeptide binding]; other site
1034836005474	Heme/copper-type cytochrome/quinol oxidases, subunit 1 [Energy production and conversion]; Region: CyoB; COG0843
1034836005475	Ubiquinol oxidase subunit I.  Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane.  It catalyzes the reduction of O2 and simultaneously pumps protons...; Region: Ubiquinol_Oxidase_I; cd01662
1034836005476	D-pathway; other site
1034836005477	Putative ubiquinol binding site [chemical binding]; other site
1034836005478	Low-spin heme (heme b) binding site [chemical binding]; other site
1034836005479	Putative water exit pathway; other site
1034836005480	Binuclear center (heme o3/CuB) [ion binding]; other site
1034836005481	K-pathway; other site
1034836005482	Putative proton exit pathway; other site
1034836005483	Heme/copper-type cytochrome/quinol oxidases, subunit 2 [Energy production and conversion]; Region: CyoA; COG1622
1034836005484	Cytochrome C oxidase subunit II, periplasmic domain; Region: COX2; pfam00116
1034836005485	Cytochrome c; Region: Cytochrom_C; pfam00034
1034836005486	protoheme IX farnesyltransferase; Provisional; Region: PRK04375
1034836005487	UbiA prenyltransferase family; Region: UbiA; pfam01040
1034836005488	Uncharacterized protein required for cytochrome oxidase assembly [Posttranslational modification, protein turnover, chaperones]; Region: CtaA; COG1612
1034836005489	Cytochrome oxidase assembly protein; Region: COX15-CtaA; pfam02628
1034836005490	pyruvate carboxylase; Reviewed; Region: PRK12999
1034836005491	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1034836005492	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
1034836005493	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
1034836005494	Pyruvate carboxylase and Transcarboxylase 5S, carboxyltransferase domain; Region: DRE_TIM_PC_TC_5S; cd07937
1034836005495	active site
1034836005496	catalytic residues [active]
1034836005497	metal binding site [ion binding]; metal-binding site
1034836005498	homodimer binding site [polypeptide binding]; other site
1034836005499	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
1034836005500	carboxyltransferase (CT) interaction site; other site
1034836005501	biotinylation site [posttranslational modification]; other site
1034836005502	Cell cycle protein; Region: FTSW_RODA_SPOVE; pfam01098
1034836005503	hypothetical protein; Provisional; Region: PRK13666
1034836005504	Glutaminase [Amino acid transport and metabolism]; Region: GlsA; COG2066
1034836005505	glutaminase A; Region: Gln_ase; TIGR03814
1034836005506	NYN ribonuclease and ATPase of PhoH family domains [General    function prediction only]; Region: COG1875
1034836005507	PIN domain of bacterial Smg6-like homologs with PhoH-like ATPase domains; Region: PIN_PhoHL-ATPase; cd09883
1034836005508	putative active site [active]
1034836005509	PhoH-like protein; Region: PhoH; pfam02562
1034836005510	sporulation lipoprotein, YhcN/YlaJ family; Region: spore_YhcN_YlaJ; TIGR02898
1034836005511	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ); Region: Spore_YhcN_YlaJ; pfam09580
1034836005512	Uncharacterized protein conserved in bacteria (DUF2197); Region: DUF2197; pfam09963
1034836005513	YlaH-like protein; Region: YlaH; pfam14036
1034836005514	Predicted membrane GTPase involved in stress response [Signal transduction mechanisms]; Region: TypA; COG1217
1034836005515	Tyrosine phosphorylated protein A (TypA)/BipA family belongs to ribosome-binding GTPases; Region: TypA_BipA; cd01891
1034836005516	G1 box; other site
1034836005517	putative GEF interaction site [polypeptide binding]; other site
1034836005518	GTP/Mg2+ binding site [chemical binding]; other site
1034836005519	Switch I region; other site
1034836005520	G2 box; other site
1034836005521	G3 box; other site
1034836005522	Switch II region; other site
1034836005523	G4 box; other site
1034836005524	G5 box; other site
1034836005525	BipA_TypA_II: domain II of BipA (also called TypA) having homology to domain II of the elongation factors (EFs) EF-G and EF-Tu.  BipA is a highly conserved protein with global regulatory properties in Escherichia coli. BipA is phosphorylated on a...; Region: BipA_TypA_II; cd03691
1034836005526	BipA_TypA_C: a C-terminal portion of BipA or TypA having homology to the C terminal domains of the elongation factors EF-G and EF-2. A member of the ribosome binding GTPase superfamily, BipA is widely distributed in bacteria and plants.  BipA is a highly...; Region: BipA_TypA_C; cd03710
1034836005527	Putative zinc-finger; Region: zf-HC2; pfam13490
1034836005528	Zinc metalloprotease (elastase) [Amino acid transport and metabolism]; Region: LasB; COG3227
1034836005529	Fungalysin/Thermolysin Propeptide Motif; Region: FTP; pfam07504
1034836005530	Peptidase propeptide and YPEB domain; Region: PepSY; pfam03413
1034836005531	Peptidase M4 family includes thermolysin, protealysin, aureolysin and neutral protease; Region: M4_neutral_protease; cd09597
1034836005532	active site
1034836005533	Zn binding site [ion binding]; other site
1034836005534	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1034836005535	Coenzyme A binding pocket [chemical binding]; other site
1034836005536	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
1034836005537	Inositol-monophosphatase-like domains. This family of phosphatases is dependent on bivalent metal ions such as Mg++, and many members are inhibited by Li+ (which is thought to displace a bivalent ion in the active site). Substrates include fructose-1; Region: IMPase_like; cd01637
1034836005538	active site
1034836005539	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4493
1034836005540	Protein of unknown function (DUF1054); Region: DUF1054; pfam06335
1034836005541	Uncharacterized protein family (UPF0223); Region: UPF0223; pfam05256
1034836005542	Arginine/lysine/ornithine decarboxylases [Amino acid transport and metabolism]; Region: LdcC; COG1982
1034836005543	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
1034836005544	homodimer interface [polypeptide binding]; other site
1034836005545	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1034836005546	catalytic residue [active]
1034836005547	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
1034836005548	Domain of unknown function (DUF4182); Region: DUF4182; pfam13790
1034836005549	Predicted xylanase/chitin deacetylase [Carbohydrate transport and metabolism]; Region: CDA1; COG0726
1034836005550	Catalytic NodB homology domain of rhizobial NodB-like proteins; Region: CE4_NodB_like_6s_7s; cd10917
1034836005551	NodB motif; other site
1034836005552	active site
1034836005553	catalytic site [active]
1034836005554	metal binding site [ion binding]; metal-binding site
1034836005555	dihydrolipoamide dehydrogenase; Reviewed; Region: PRK06416
1034836005556	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
1034836005557	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1034836005558	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
1034836005559	branched-chain alpha-keto acid dehydrogenase subunit E2; Reviewed; Region: PRK11856
1034836005560	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1034836005561	E3 interaction surface; other site
1034836005562	lipoyl attachment site [posttranslational modification]; other site
1034836005563	e3 binding domain; Region: E3_binding; pfam02817
1034836005564	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
1034836005565	Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit [Energy production and conversion]; Region: AcoB; COG0022
1034836005566	Pyrimidine (PYR) binding domain of the beta subunits of the E1 components of human pyruvate dehydrogenase complex (E1- PDHc) and related proteins; Region: TPP_PYR_E1-PDHc-beta_like; cd07036
1034836005567	alpha subunit interface [polypeptide binding]; other site
1034836005568	TPP binding site [chemical binding]; other site
1034836005569	heterodimer interface [polypeptide binding]; other site
1034836005570	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1034836005571	pyruvate dehydrogenase E1 component, alpha subunit; Region: PDH_E1_alph_x; TIGR03181
1034836005572	Thiamine pyrophosphate (TPP) family, E1 of PDC_ADC_BCADC subfamily, TPP-binding module; composed of proteins similar to the E1 components of the human pyruvate dehydrogenase complex (PDC), the acetoin dehydrogenase complex (ADC) and the branched chain...; Region: TPP_E1_PDC_ADC_BCADC; cd02000
1034836005573	TPP-binding site [chemical binding]; other site
1034836005574	tetramer interface [polypeptide binding]; other site
1034836005575	heterodimer interface [polypeptide binding]; other site
1034836005576	phosphorylation loop region [posttranslational modification]
1034836005577	Putative cell-wall binding lipoprotein; Region: YkyA; pfam10368
1034836005578	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
1034836005579	active site
1034836005580	catalytic residues [active]
1034836005581	metal binding site [ion binding]; metal-binding site
1034836005582	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cl17915
1034836005583	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
1034836005584	motif II; other site
1034836005585	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1034836005586	5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase; Region: PLN02475
1034836005587	hypothetical protein; Provisional; Region: PRK13667
1034836005588	mRNA degradation ribonucleases J1/J2 (metallo-beta-lactamase superfamily) [Translation, ribosomal structure and biogenesis; Replication, recombination and repair]; Region: COG0595
1034836005589	Metallo-beta-lactamase superfamily; Region: Lactamase_B; pfam00753
1034836005590	RNA-metabolising metallo-beta-lactamase; Region: RMMBL; pfam07521
1034836005591	adenine deaminase; Region: ade; TIGR01178
1034836005592	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1034836005593	Adenine deaminase (AdeC) directly deaminates adenine to form hypoxanthine. This reaction is part of one of the adenine salvage pathways, as well as the degradation pathway. It is important for adenine utilization as a purine, as well as a nitrogen source...; Region: AdeC; cd01295
1034836005594	active site
1034836005595	Adenine deaminase C-terminal domain; Region: Adenine_deam_C; pfam13382
1034836005596	K+ transport systems, NAD-binding component [Inorganic ion transport and metabolism]; Region: TrkA; COG0569
1034836005597	TrkA-N domain; Region: TrkA_N; pfam02254
1034836005598	TrkA-C domain; Region: TrkA_C; pfam02080
1034836005599	GGCT-like domains, also called AIG2-like family. Gamma-glutamyl cyclotransferase (GGCT) catalyzes the formation of pyroglutamic acid (5-oxoproline) from dipeptides containing gamma-glutamyl, and is a dimeric protein. In Homo sapiens, the protein is...; Region: GGCT_like; cd06661
1034836005600	putative active site pocket [active]
1034836005601	dimerization interface [polypeptide binding]; other site
1034836005602	GGCT-like domains, also called AIG2-like family. Gamma-glutamyl cyclotransferase (GGCT) catalyzes the formation of pyroglutamic acid (5-oxoproline) from dipeptides containing gamma-glutamyl, and is a dimeric protein. In Homo sapiens, the protein is...; Region: GGCT_like; cd06661
1034836005603	putative active site pocket [active]
1034836005604	dimerization interface [polypeptide binding]; other site
1034836005605	putative catalytic residue [active]
1034836005606	PAS fold; Region: PAS; pfam00989
1034836005607	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1034836005608	putative active site [active]
1034836005609	heme pocket [chemical binding]; other site
1034836005610	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1034836005611	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1034836005612	dimer interface [polypeptide binding]; other site
1034836005613	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1034836005614	ATP binding site [chemical binding]; other site
1034836005615	Mg2+ binding site [ion binding]; other site
1034836005616	G-X-G motif; other site
1034836005617	Regulators of stationary/sporulation gene expression [Transcription]; Region: AbrB; COG2002
1034836005618	SpoVT / AbrB like domain; Region: SpoVT_AbrB; smart00966
1034836005619	CRISPR/Cas system-associated protein Cas1; Region: Cas1_I-II-III; cl00656
1034836005620	rod-share determining protein MreBH; Provisional; Region: PRK13929
1034836005621	MreB and similar proteins; Region: MreB_like; cd10225
1034836005622	nucleotide binding site [chemical binding]; other site
1034836005623	Mg binding site [ion binding]; other site
1034836005624	putative protofilament interaction site [polypeptide binding]; other site
1034836005625	RodZ interaction site [polypeptide binding]; other site
1034836005626	Thermophilic metalloprotease (M29); Region: Peptidase_M29; pfam02073
1034836005627	Leucyl aminopeptidase (aminopeptidase T) [Amino acid transport and metabolism]; Region: AmpS; COG2309
1034836005628	2-dehydropantoate 2-reductase; Provisional; Region: PRK12921
1034836005629	Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558
1034836005630	Ketopantoate reductase PanE/ApbA C terminal; Region: ApbA_C; pfam08546
1034836005631	ABC transporter ATP-binding protein; Provisional; Region: PRK15064
1034836005632	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1034836005633	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1034836005634	ABC transporter; Region: ABC_tran_2; pfam12848
1034836005635	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1034836005636	signal peptidase I, bacterial type; Region: sigpep_I_bact; TIGR02227
1034836005637	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
1034836005638	Catalytic site [active]
1034836005639	PTS system 2-O-a-mannosyl-D-glycerate specific transporter subunit IIABC; Provisional; Region: PRK09765
1034836005640	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1034836005641	active site
1034836005642	phosphorylation site [posttranslational modification]
1034836005643	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
1034836005644	active site
1034836005645	P-loop; other site
1034836005646	phosphorylation site [posttranslational modification]
1034836005647	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299
1034836005648	Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) [Carbohydrate transport and metabolism]; Region: FruK; COG1105
1034836005649	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
1034836005650	putative substrate binding site [chemical binding]; other site
1034836005651	putative ATP binding site [chemical binding]; other site
1034836005652	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1034836005653	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
1034836005654	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1034836005655	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1034836005656	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
1034836005657	FtsX-like permease family; Region: FtsX; pfam02687
1034836005658	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1034836005659	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1034836005660	Walker A/P-loop; other site
1034836005661	ATP binding site [chemical binding]; other site
1034836005662	Q-loop/lid; other site
1034836005663	ABC transporter signature motif; other site
1034836005664	Walker B; other site
1034836005665	D-loop; other site
1034836005666	H-loop/switch region; other site
1034836005667	Membrane-fusion protein [Cell envelope biogenesis, outer membrane]; Region: AcrA; COG0845
1034836005668	HlyD family secretion protein; Region: HlyD_3; pfam13437
1034836005669	Yip1 domain; Region: Yip1; pfam04893
1034836005670	Ubiquitin domain of MoaD-like proteins; Region: MoaD; cd00754
1034836005671	MoaE interaction surface [polypeptide binding]; other site
1034836005672	MoeB interaction surface [polypeptide binding]; other site
1034836005673	thiocarboxylated glycine; other site
1034836005674	MoaE family. Members of this family are involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor for a diverse group of redox enzymes. Moco biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoaE; cd00756
1034836005675	MoaE homodimer interface [polypeptide binding]; other site
1034836005676	MoaD interaction [polypeptide binding]; other site
1034836005677	active site residues [active]
1034836005678	Molybdenum is an essential trace element in the form of molybdenum cofactor (Moco) which is associated with the metabolism of nitrogen, carbon and sulfur by redox active enzymes. In E. coli, the synthesis of Moco involves genes from several loci: moa; Region: MobB; cd03116
1034836005679	Walker A motif; other site
1034836005680	Molybdopterin biosynthesis enzyme [Coenzyme metabolism]; Region: MoeA; COG0303
1034836005681	MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoeA; cd00887
1034836005682	dimer interface [polypeptide binding]; other site
1034836005683	putative functional site; other site
1034836005684	putative MPT binding site; other site
1034836005685	thiamine/molybdopterin biosynthesis MoeB-like protein; Provisional; Region: PRK12475
1034836005686	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
1034836005687	ATP binding site [chemical binding]; other site
1034836005688	substrate interface [chemical binding]; other site
1034836005689	molybdopterin-guanine dinucleotide biosynthesis protein MobA; Reviewed; Region: mobA; PRK00317
1034836005690	MobA catalyzes the formation of molybdopterin guanine dinucleotide; Region: MobA; cd02503
1034836005691	GTP binding site; other site
1034836005692	chromosome segregation protein SMC, common bacterial type; Region: SMC_prok_B; TIGR02168
1034836005693	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
1034836005694	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
1034836005695	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
1034836005696	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
1034836005697	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1034836005698	hypothetical protein; Provisional; Region: PRK03094
1034836005699	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
1034836005700	M20 Peptidase Aminoacyclase-1 YkuR-like proteins, including YkuR and Ama/HipO/HyuC proteins; Region: M20_Acy1_YkuR_like; cd05670
1034836005701	metal binding site [ion binding]; metal-binding site
1034836005702	putative dimer interface [polypeptide binding]; other site
1034836005703	Tetrahydrodipicolinate succinyltransferase N-terminal; Region: DapH_N; pfam08503
1034836005704	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase; Region: DapD_Ac; TIGR03532
1034836005705	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate (THDP) N-succinyltransferase (also called THP succinyltransferase): THDP N-succinyltransferase catalyzes the conversion of tetrahydrodipicolinate and succinyl-CoA to N-succinyltetrahydrodipicolinate and CoA; Region: LbH_THP_succinylT; cd03350
1034836005706	active site
1034836005707	trimer interface [polypeptide binding]; other site
1034836005708	substrate binding site [chemical binding]; other site
1034836005709	CoA binding site [chemical binding]; other site
1034836005710	Uncharacterized flavoproteins [Energy production and conversion]; Region: FpaA; COG0426
1034836005711	flavodoxin, short chain; Region: flav_short; TIGR01753
1034836005712	BNR repeat-like domain; Region: BNR_2; pfam13088
1034836005713	flavodoxin; Provisional; Region: PRK06703
1034836005714	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1034836005715	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1034836005716	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1034836005717	dimerization interface [polypeptide binding]; other site
1034836005718	FOG: CBS domain [General function prediction only]; Region: COG0517
1034836005719	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair_30; cd04643
1034836005720	Antirepressor AbbA; Region: AbbA_antirepres; pfam14156
1034836005721	Protein of unknown function (DUF458); Region: DUF458; pfam04308
1034836005722	Protein of unknown function (DUF1797); Region: DUF1797; cl11550
1034836005723	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1034836005724	EAL-domain associated signalling protein domain; Region: YkuI_C; pfam10388
1034836005725	short chain dehydrogenase; Provisional; Region: PRK07677
1034836005726	Trans-2-enoyl-CoA reductase (TER) and 2,4-dienoyl-CoA reductase (DECR), atypical (a) SDR; Region: TER_DECR_SDR_a; cd05369
1034836005727	NAD(P) binding site [chemical binding]; other site
1034836005728	substrate binding site [chemical binding]; other site
1034836005729	homotetramer interface [polypeptide binding]; other site
1034836005730	active site
1034836005731	homodimer interface [polypeptide binding]; other site
1034836005732	phosphodiesterase YaeI; Provisional; Region: PRK11340
1034836005733	Bacillus subtilis YkuE and related proteins, C-terminal metallophosphatase domain; Region: MPP_YkuE_C; cd07385
1034836005734	putative active site [active]
1034836005735	putative metal binding site [ion binding]; other site
1034836005736	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1034836005737	Uncharacterized protein conserved in bacteria [Function unknown]; Region: ErfK; COG1376
1034836005738	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
1034836005739	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1034836005740	H+ Antiporter protein; Region: 2A0121; TIGR00900
1034836005741	putative substrate translocation pore; other site
1034836005742	YkyB-like protein; Region: YkyB; pfam14177
1034836005743	CheW, a small regulator protein, unique to the chemotaxis signalling in prokaryotes and archea. CheW interacts with the histidine kinase CheA, most likely with the related regulatory domain of CheA. CheW is proposed to form signalling arrays together...; Region: CheW; cd00732
1034836005744	putative CheA interaction surface; other site
1034836005745	Response regulator receiver domain; Region: Response_reg; pfam00072
1034836005746	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1034836005747	active site
1034836005748	phosphorylation site [posttranslational modification]
1034836005749	intermolecular recognition site; other site
1034836005750	dimerization interface [polypeptide binding]; other site
1034836005751	aminotransferase A; Validated; Region: PRK07683
1034836005752	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1034836005753	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1034836005754	homodimer interface [polypeptide binding]; other site
1034836005755	catalytic residue [active]
1034836005756	FOG: PAS/PAC domain [Signal transduction mechanisms]; Region: AtoS; COG2202
1034836005757	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1034836005758	putative active site [active]
1034836005759	heme pocket [chemical binding]; other site
1034836005760	FOG: PAS/PAC domain [Signal transduction mechanisms]; Region: AtoS; COG2202
1034836005761	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1034836005762	putative active site [active]
1034836005763	heme pocket [chemical binding]; other site
1034836005764	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1034836005765	putative active site [active]
1034836005766	heme pocket [chemical binding]; other site
1034836005767	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1034836005768	dimer interface [polypeptide binding]; other site
1034836005769	phosphorylation site [posttranslational modification]
1034836005770	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1034836005771	ATP binding site [chemical binding]; other site
1034836005772	Mg2+ binding site [ion binding]; other site
1034836005773	G-X-G motif; other site
1034836005774	Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane]; Region: FtsI; COG0768
1034836005775	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
1034836005776	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
1034836005777	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
1034836005778	Uncharacterized protein with SCP/PR1 domains [Function unknown]; Region: COG2340
1034836005779	SCP_bacterial: SCP-like extracellular protein domain, as found in bacteria and archaea. The wider family of SCP containing proteins includes plant pathogenesis-related protein 1 (PR-1), CRISPs, mammalian cysteine-rich secretory proteins, and allergen 5...; Region: SCP_bacterial; cd05379
1034836005780	3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases [Lipid metabolism]; Region: MmsB; COG2084
1034836005781	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
1034836005782	Cache domain; Region: Cache_1; pfam02743
1034836005783	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1034836005784	dimerization interface [polypeptide binding]; other site
1034836005785	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1034836005786	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1034836005787	dimer interface [polypeptide binding]; other site
1034836005788	putative CheW interface [polypeptide binding]; other site
1034836005789	DNA repair photolyase [DNA replication, recombination, and repair]; Region: SplB; COG1533
1034836005790	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1034836005791	FeS/SAM binding site; other site
1034836005792	Transcriptional regulator protein (SplA); Region: SplA; pfam11132
1034836005793	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism]; Region: PtsA; COG1080
1034836005794	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
1034836005795	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
1034836005796	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
1034836005797	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
1034836005798	dimerization domain swap beta strand [polypeptide binding]; other site
1034836005799	regulatory protein interface [polypeptide binding]; other site
1034836005800	active site
1034836005801	regulatory phosphorylation site [posttranslational modification]; other site
1034836005802	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1034836005803	PTS system, glucose-specific IIBC component; Region: PTS-II-BC-glcB; TIGR02002
1034836005804	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1034836005805	active site turn [active]
1034836005806	phosphorylation site [posttranslational modification]
1034836005807	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210
1034836005808	HPr interaction site; other site
1034836005809	glycerol kinase (GK) interaction site [polypeptide binding]; other site
1034836005810	active site
1034836005811	phosphorylation site [posttranslational modification]
1034836005812	CAT RNA binding domain; Region: CAT_RBD; pfam03123
1034836005813	transcriptional antiterminator BglG; Provisional; Region: PRK09772
1034836005814	PRD domain; Region: PRD; pfam00874
1034836005815	PRD domain; Region: PRD; pfam00874
1034836005816	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1034836005817	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1034836005818	DNA binding site [nucleotide binding]
1034836005819	domain linker motif; other site
1034836005820	Ligand-binding domain of a novel transcription factor implicated in catabolite repression in Bacillus and Clostridium species; Region: PBP1_CcpB_like; cd06286
1034836005821	putative dimerization interface [polypeptide binding]; other site
1034836005822	putative ligand binding site [chemical binding]; other site
1034836005823	Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006
1034836005824	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
1034836005825	Similar to Prolidase and Aminopeptidase P. The members of this subfamily presumably catalyse hydrolysis of Xaa-Pro dipeptides and/or release of any N-terminal amino acid, including proline, that is linked with proline; Region: APP-like; cd01092
1034836005826	active site
1034836005827	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217
1034836005828	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1034836005829	Soluble P-type ATPase [General function prediction only]; Region: COG4087
1034836005830	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
1034836005831	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
1034836005832	catalytic residues [active]
1034836005833	Stage V sporulation protein B, also known as Stage III sporulation protein F, and related proteins; Region: MATE_SpoVB_like; cd13124
1034836005834	Cell wall hydrolyses involved in spore germination [Cell envelope biogenesis, outer membrane]; Region: SleB; COG3773
1034836005835	Cell Wall Hydrolase; Region: Hydrolase_2; pfam07486
1034836005836	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4873
1034836005837	Protein of unknown function (DUF3219); Region: DUF3219; pfam11514
1034836005838	Enzyme related to GTP cyclohydrolase I [General function prediction only]; Region: COG0780
1034836005839	7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE; Region: Bsubt_queE; TIGR03365
1034836005840	putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE; Region: rSAM_QueE_Ecoli; TIGR04322
1034836005841	6-pyruvoyl tetrahydropterin synthase/QueD family protein; Region: 6PTHBS; TIGR00039
1034836005842	active site
1034836005843	ExsB is a transcription regulator related protein. It is a subfamily of a Adenosine nucleotide binding superfamily of proteins. This protein family is represented by a single member in nearly every completed large (> 1000 genes) prokaryotic genome. In...; Region: ExsB; cd01995
1034836005844	Ligand Binding Site [chemical binding]; other site
1034836005845	Uncharacterized membrane protein [Function unknown]; Region: COG3949
1034836005846	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1034836005847	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
1034836005848	Walker A motif; other site
1034836005849	ATP binding site [chemical binding]; other site
1034836005850	Walker B motif; other site
1034836005851	arginine finger; other site
1034836005852	UvrB/uvrC motif; Region: UVR; pfam02151
1034836005853	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1034836005854	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
1034836005855	Walker A motif; other site
1034836005856	ATP binding site [chemical binding]; other site
1034836005857	Walker B motif; other site
1034836005858	arginine finger; other site
1034836005859	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
1034836005860	flagellar motor protein MotA; Validated; Region: PRK08124
1034836005861	MotA/TolQ/ExbB proton channel family; Region: MotA_ExbB; cl00568
1034836005862	flagellar motor protein MotB; Reviewed; Region: motB; PRK07734
1034836005863	Membrane MotB of proton-channel complex MotA/MotB; Region: MotB_plug; pfam13677
1034836005864	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1034836005865	ligand binding site [chemical binding]; other site
1034836005866	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1034836005867	MarR family; Region: MarR; pfam01047
1034836005868	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1034836005869	dimer interface [polypeptide binding]; other site
1034836005870	phosphorylation site [posttranslational modification]
1034836005871	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1034836005872	ATP binding site [chemical binding]; other site
1034836005873	Mg2+ binding site [ion binding]; other site
1034836005874	G-X-G motif; other site
1034836005875	Spo0E like sporulation regulatory protein; Region: SpoOE-like; pfam09388
1034836005876	Uncharacterized conserved protein, contains double-stranded beta-helix domain [Function unknown]; Region: COG1791
1034836005877	Cupin domain; Region: Cupin_2; pfam07883
1034836005878	methylthioribulose-1-phosphate dehydratase; Reviewed; Region: mtnB; PRK06754
1034836005879	intersubunit interface [polypeptide binding]; other site
1034836005880	active site
1034836005881	Zn2+ binding site [ion binding]; other site
1034836005882	haloacid dehalogenase-like hydrolase; Region: Hydrolase; pfam00702
1034836005883	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1034836005884	motif II; other site
1034836005885	2,3-diketo-5-methylthiopentyl-1-phosphate enolase; Reviewed; Region: mtnW; PRK09549
1034836005886	2,3-diketo-5-methylthiopentyl-1-phosphate enolase; Region: RLP_DK-MTP-1-P-enolase; cd08209
1034836005887	dimer interface [polypeptide binding]; other site
1034836005888	active site
1034836005889	catalytic residue [active]
1034836005890	metal binding site [ion binding]; metal-binding site
1034836005891	transaminase; Reviewed; Region: PRK08068
1034836005892	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1034836005893	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1034836005894	homodimer interface [polypeptide binding]; other site
1034836005895	catalytic residue [active]
1034836005896	Predicted amidohydrolase [General function prediction only]; Region: COG0388
1034836005897	Uncharacterized subgroup of the nitrilase superfamily (putative class 13 nitrilases); Region: nitrilase_5; cd07583
1034836005898	putative active site [active]
1034836005899	catalytic triad [active]
1034836005900	putative dimer interface [polypeptide binding]; other site
1034836005901	methylthioribose kinase; Reviewed; Region: mtnK; PRK09550
1034836005902	Phosphotransferase enzyme family; Region: APH; pfam01636
1034836005903	methylthioribose-1-phosphate isomerase; Reviewed; Region: mtnA; PRK05720
1034836005904	S-methyl-5-thioribose-1-phosphate isomerase; Region: salvage_mtnA; TIGR00512
1034836005905	6-O-methylguanine DNA methyltransferase, ribonuclease-like domain; Region: Methyltransf_1N; pfam02870
1034836005906	methylated-DNA--protein-cysteine methyltransferase; Provisional; Region: PRK00901
1034836005907	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
1034836005908	DNA binding site [nucleotide binding]
1034836005909	active site
1034836005910	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1034836005911	FOG: PAS/PAC domain [Signal transduction mechanisms]; Region: AtoS; COG2202
1034836005912	putative active site [active]
1034836005913	heme pocket [chemical binding]; other site
1034836005914	PAS domain; Region: PAS; smart00091
1034836005915	FOG: PAS/PAC domain [Signal transduction mechanisms]; Region: AtoS; COG2202
1034836005916	PAS domain; Region: PAS; smart00091
1034836005917	Signal transduction histidine kinase, nitrogen specific [Signal transduction mechanisms]; Region: NtrB; COG3852
1034836005918	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1034836005919	dimer interface [polypeptide binding]; other site
1034836005920	phosphorylation site [posttranslational modification]
1034836005921	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1034836005922	ATP binding site [chemical binding]; other site
1034836005923	Mg2+ binding site [ion binding]; other site
1034836005924	G-X-G motif; other site
1034836005925	Fucose 4-O-acetylase and related acetyltransferases [Carbohydrate transport and metabolism]; Region: NolL; COG3594
1034836005926	Acyltransferase family; Region: Acyl_transf_3; pfam01757
1034836005927	Predicted membrane protein [Function unknown]; Region: COG2323
1034836005928	Trk-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: TrkG; COG0168
1034836005929	potassium uptake protein, TrkH family; Region: 2a38; TIGR00933
1034836005930	heat shock protein HtpX; Provisional; Region: PRK05457
1034836005931	Domain of unknown function (DUF1836); Region: DUF1836; pfam08876
1034836005932	Small, acid-soluble spore proteins, alpha/beta type; Region: SASP; pfam00269
1034836005933	Anti-sigma factor N-terminus; Region: RsgI_N; pfam12791
1034836005934	putative RNA polymerase sigma factor SigI; Reviewed; Region: PRK08311
1034836005935	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1034836005936	integral membrane protein, YkoY family; Region: R_switched_YkoY; TIGR03716
1034836005937	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1034836005938	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
1034836005939	MHYT domain (predicted integral membrane sensor domain) [Signal transduction mechanisms]; Region: COG3300
1034836005940	Bacterial signalling protein N terminal repeat; Region: MHYT; pfam03707
1034836005941	Bacterial signalling protein N terminal repeat; Region: MHYT; pfam03707
1034836005942	PAS domain; Region: PAS_9; pfam13426
1034836005943	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1034836005944	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1034836005945	metal binding site [ion binding]; metal-binding site
1034836005946	active site
1034836005947	I-site; other site
1034836005948	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1034836005949	Ku-homolog [Replication, recombination, and repair]; Region: COG1273
1034836005950	Ku-core domain, Ku-like subfamily; composed of prokaryotic homologs of the eukaryotic DNA binding protein Ku. The alignment includes the core domain shared by the prokaryotic YkoV-like proteins and the eukaryotic Ku70 and Ku80. The prokaryotic Ku...; Region: KU_like; cd00789
1034836005951	putative DNA binding site [nucleotide binding]; other site
1034836005952	putative homodimer interface [polypeptide binding]; other site
1034836005953	ATP-dependent DNA ligase; Reviewed; Region: ligD; PRK09633
1034836005954	Adenylation domain of Mycobacterium tuberculosis LigD and LigC-like ATP-dependent DNA ligases; Region: Adenylation_DNA_ligase_LigD_LigC; cd07906
1034836005955	active site
1034836005956	DNA binding site [nucleotide binding]
1034836005957	LigD_Pol_like_3: Polymerase (Pol) domain of bacterial LigD proteins similar to Pseudomonas aeruginosa (Pae) LigD, subgroup 3. The LigD Pol domain belongs to the archaeal/eukaryal primase (AEP) superfamily. In prokaryotes, LigD along with Ku is required...; Region: LigD_Pol_like_3; cd04866
1034836005958	nucleotide binding site [chemical binding]; other site
1034836005959	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1034836005960	MarR family; Region: MarR; pfam01047
1034836005961	Helix-Turn-Helix DNA binding domain of GlnR-like transcription regulators; Region: HTH_GlnR-like; cd01105
1034836005962	Predicted transcriptional regulators [Transcription]; Region: SoxR; COG0789
1034836005963	DNA binding residues [nucleotide binding]
1034836005964	putative dimer interface [polypeptide binding]; other site
1034836005965	Mg2+ transporter (mgtE); Region: mgtE; TIGR00400
1034836005966	MgtE intracellular N domain; Region: MgtE_N; smart00924
1034836005967	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domain in the magnesium transporter, MgtE.  MgtE and its homologs are found in eubacteria, archaebacteria, and eukaryota. Members of this family transport Mg2+ or other...; Region: CBS_pair_Mg_transporter; cd04606
1034836005968	Divalent cation transporter; Region: MgtE; pfam01769
1034836005969	Transcriptional regulator protein (SplA); Region: SplA; pfam11132
1034836005970	Predicted glycosyl hydrolase [General function prediction only]; Region: COG3858
1034836005971	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1034836005972	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1034836005973	Cortical fragment-lytic enzyme (CFLE) is a peptidoglycan hydrolase involved in  bacterial endospore germination.  CFLE is expressed as an inactive preprotein (called SleB) in the forespore compartment of sporulating cells.  SleB translocates across the...; Region: GH18_CFLE_spore_hydrolase; cd02874
1034836005974	active site
1034836005975	ABC-type cobalt transport system, permease component; Region: ABC_cobalt; cl01943
1034836005976	ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only]; Region: COG1123
1034836005977	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
1034836005978	Walker A/P-loop; other site
1034836005979	ATP binding site [chemical binding]; other site
1034836005980	Q-loop/lid; other site
1034836005981	ABC transporter signature motif; other site
1034836005982	Walker B; other site
1034836005983	D-loop; other site
1034836005984	H-loop/switch region; other site
1034836005985	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
1034836005986	Walker A/P-loop; other site
1034836005987	ATP binding site [chemical binding]; other site
1034836005988	Q-loop/lid; other site
1034836005989	ABC transporter signature motif; other site
1034836005990	Walker B; other site
1034836005991	D-loop; other site
1034836005992	H-loop/switch region; other site
1034836005993	Cobalt transport protein; Region: CbiQ; pfam02361
1034836005994	Sulphate Transporter and Anti-Sigma factor antagonist domain of the "stressosome" complex proteins RsbS and RsbR, regulators of the bacterial stress activated alternative sigma factor sigma-B by phosphorylation; Region: STAS_RsbR_RsbS_like; cd07041
1034836005995	Peptidase S8 family domain in Subtilisin proteins; Region: Peptidases_S8_Subtilisin_subset; cd07477
1034836005996	active site
1034836005997	catalytic residues [active]
1034836005998	5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase; Provisional; Region: PRK05222
1034836005999	CIMS - Cobalamine-independent methonine synthase, or MetE, N-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_N_terminal_like; cd03312
1034836006000	THF binding site; other site
1034836006001	CIMS - Cobalamine-independent methonine synthase, or MetE, C-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_C_terminal_like; cd03311
1034836006002	substrate binding site [chemical binding]; other site
1034836006003	THF binding site; other site
1034836006004	zinc-binding site [ion binding]; other site
1034836006005	DNA-binding transcriptional activator YeiL; Provisional; Region: PRK10402
1034836006006	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
1034836006007	ligand binding site [chemical binding]; other site
1034836006008	flexible hinge region; other site
1034836006009	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cl17320
1034836006010	putative 3-phenylpropionic acid transporter; Provisional; Region: PRK11128
1034836006011	Carbohydrate binding domain; Region: CBM_5_12; pfam02839
1034836006012	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
1034836006013	UDP-glucose LOS-beta-1,4 glucosyltransferase is required for biosynthesis of lipooligosaccharide; Region: Beta4Glucosyltransferase; cd02511
1034836006014	putative metal binding site; other site
1034836006015	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1034836006016	binding surface
1034836006017	TPR motif; other site
1034836006018	TPR repeat; Region: TPR_11; pfam13414
1034836006019	peroxiredoxin, Ohr subfamily; Region: organ_hyd_perox; TIGR03561
1034836006020	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1034836006021	MarR family; Region: MarR; pfam01047
1034836006022	peroxiredoxin, Ohr subfamily; Region: organ_hyd_perox; TIGR03561
1034836006023	Gamma-glutamyl phosphate reductase (GPR), aldehyde dehydrogenase families 18 and 19; Region: ALDH_F18-19_ProA-GPR; cd07079
1034836006024	gamma-glutamyl phosphate reductase; Region: proA; TIGR00407
1034836006025	putative catalytic cysteine [active]
1034836006026	gamma-glutamyl kinase; Provisional; Region: PRK05429
1034836006027	AAK_G5K_ProB: Glutamate-5-kinase (G5K) catalyzes glutamate-dependent ATP cleavage; G5K transfers the terminal phosphoryl group of ATP to the gamma-carboxyl group of glutamate, in the first and controlling step of proline (and, in mammals, ornithine)...; Region: AAK_G5K_ProB; cd04242
1034836006028	nucleotide binding site [chemical binding]; other site
1034836006029	homotetrameric interface [polypeptide binding]; other site
1034836006030	putative phosphate binding site [ion binding]; other site
1034836006031	putative allosteric binding site; other site
1034836006032	PUA domain; Region: PUA; pfam01472
1034836006033	formyltetrahydrofolate deformylase; Reviewed; Region: purU; PRK06027
1034836006034	N-terminal ACT domain of formyltetrahydrofolate deformylase (F4HF-DF; formyltetrahydrofolate hydrolase); Region: ACT_F4HF-DF; cd04875
1034836006035	Formyltetrahydrofolate deformylase (Formyl-FH4 hydrolase), C-terminal hydrolase domain; Region: FMT_core_Formyl-FH4-Hydrolase_C; cd08648
1034836006036	putative active site [active]
1034836006037	putative substrate binding site [chemical binding]; other site
1034836006038	putative cosubstrate binding site; other site
1034836006039	catalytic site [active]
1034836006040	Membrane transporters of cations and cationic drugs [Inorganic ion transport and metabolism]; Region: EmrE; COG2076
1034836006041	Small Multidrug Resistance protein; Region: Multi_Drug_Res; pfam00893
1034836006042	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1034836006043	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
1034836006044	Brown fat-inducible thioesterase (BFIT).  Brain acyl-CoA hydrolase (BACH).  These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis; Region: BFIT_BACH; cd03442
1034836006045	N-Dimethylarginine dimethylaminohydrolase [Amino acid transport and metabolism]; Region: COG1834
1034836006046	Amidinotransferase; Region: Amidinotransf; pfam02274
1034836006047	Lactonase, 7-bladed beta-propeller; Region: Lactonase; pfam10282
1034836006048	ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism]; Region: AppF; COG4608
1034836006049	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1034836006050	Walker A/P-loop; other site
1034836006051	ATP binding site [chemical binding]; other site
1034836006052	Q-loop/lid; other site
1034836006053	ABC transporter signature motif; other site
1034836006054	Walker B; other site
1034836006055	D-loop; other site
1034836006056	H-loop/switch region; other site
1034836006057	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1034836006058	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
1034836006059	NlpC/P60 family; Region: NLPC_P60; pfam00877
1034836006060	L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily [Cell envelope biogenesis, outer membrane / General function prediction only]; Region: COG4948
1034836006061	L-Ala-D/L-Glu epimerase catalyzes the epimerization of L-Ala-D/L-Glu and other dipeptides. The genomic context and the substrate specificity of characterized members of this family from E.coli and B.subtilis indicates a possible role in the metabolism of...; Region: L-Ala-DL-Glu_epimerase; cd03319
1034836006062	active site
1034836006063	LD-Carboxypeptidase, a serine protease, includes microcin C7 self immunity protein; Region: Peptidase_S66; cd07025
1034836006064	dimer interface [polypeptide binding]; other site
1034836006065	catalytic triad [active]
1034836006066	potential frameshift: common BLAST hit: gi|154685714|ref|YP_001420875.1| DppE
1034836006067	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppD; COG0444
1034836006068	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1034836006069	Walker A/P-loop; other site
1034836006070	ATP binding site [chemical binding]; other site
1034836006071	Q-loop/lid; other site
1034836006072	ABC transporter signature motif; other site
1034836006073	Walker B; other site
1034836006074	D-loop; other site
1034836006075	H-loop/switch region; other site
1034836006076	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1034836006077	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
1034836006078	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
1034836006079	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1034836006080	dimer interface [polypeptide binding]; other site
1034836006081	conserved gate region; other site
1034836006082	putative PBP binding loops; other site
1034836006083	ABC-ATPase subunit interface; other site
1034836006084	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
1034836006085	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1034836006086	dimer interface [polypeptide binding]; other site
1034836006087	conserved gate region; other site
1034836006088	putative PBP binding loops; other site
1034836006089	ABC-ATPase subunit interface; other site
1034836006090	Peptidase M55, D-aminopeptidase dipeptide-binding protein family; Region: DAP_dppA; cd00281
1034836006091	SxDxEG motif; other site
1034836006092	active site
1034836006093	metal binding site [ion binding]; metal-binding site
1034836006094	homopentamer interface [polypeptide binding]; other site
1034836006095	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1034836006096	putative substrate translocation pore; other site
1034836006097	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1034836006098	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
1034836006099	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1034836006100	protein binding site [polypeptide binding]; other site
1034836006101	undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional; Region: PRK10714
1034836006102	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
1034836006103	Ligand binding site; other site
1034836006104	Putative Catalytic site; other site
1034836006105	DXD motif; other site
1034836006106	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family [Cell envelope biogenesis, outer membrane]; Region: ArnT; COG1807
1034836006107	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; pfam13231
1034836006108	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family [Cell envelope biogenesis, outer membrane]; Region: ArnT; COG1807
1034836006109	N-terminal domain of Sphingobium chlorophenolicum 2,6-dichloro-p-hydroquinone 1,2-dioxygenase (PcpA), and similar proteins; Region: PcpA_N_like; cd08346
1034836006110	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1034836006111	Zn binding site [ion binding]; other site
1034836006112	C-terminal domain of Sphingobium chlorophenolicum 2,6-dichloro-p-hydroquinone 1,2-dioxygenase (PcpA), and similar proteins; Region: PcpA_C_like; cd08347
1034836006113	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1034836006114	Zn binding site [ion binding]; other site
1034836006115	putative fructoselysine transporter; Provisional; Region: frlA; PRK11357
1034836006116	Phosphate transport regulator (distant homolog of PhoU) [Inorganic ion transport and metabolism]; Region: COG1392
1034836006117	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
1034836006118	Toxin SpoIISA, type II toxin-antitoxin system; Region: SpoIISA_toxin; pfam14171
1034836006119	Antitoxin SpoIISB, type II toxin-antitoxin system; Region: SpoIISB_antitox; pfam14185
1034836006120	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
1034836006121	amidase catalytic site [active]
1034836006122	Zn binding residues [ion binding]; other site
1034836006123	substrate binding site [chemical binding]; other site
1034836006124	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1034836006125	Putative peptidoglycan-binding domain-containing protein [Cell envelope biogenesis, outer membrane]; Region: COG3409
1034836006126	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
1034836006127	Phage lysis protein, holin; Region: Phage_holin; pfam04688
1034836006128	Haemolysin XhlA; Region: XhlA; pfam10779
1034836006129	Phage uncharacterized protein (Phage_XkdX); Region: Phage_XkdX; cl09900
1034836006130	XkdW protein; Region: XkdW; pfam09636
1034836006131	Uncharacterized protein conserved in bacteria (DUF2313); Region: DUF2313; pfam10076
1034836006132	Uncharacterized homolog of phage Mu protein gp47 [Function unknown]; Region: XkdT; COG3299
1034836006133	Protein of unknown function (DUF2634); Region: DUF2634; pfam10934
1034836006134	Protein of unknown function (DUF2577); Region: DUF2577; pfam10844
1034836006135	Uncharacterized protein containing LysM domain [Function unknown]; Region: XkdP; COG1652
1034836006136	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1034836006137	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
1034836006138	AAA ATPase domain; Region: AAA_15; pfam13175
1034836006139	membrane protein P6; Region: PHA01399
1034836006140	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1034836006141	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
1034836006142	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1034836006143	catalytic residue [active]
1034836006144	Phage XkdN-like protein; Region: XkdN; pfam08890
1034836006145	Protein of unknown function (DUF2001); Region: DUF2001; pfam09393
1034836006146	Phage tail sheath protein; Region: Phage_sheath_1; pfam04984
1034836006147	Predicted P-loop ATPase fused to an acetyltransferase [General function prediction only]; Region: COG1444
1034836006148	Domain of unknown function (DUF3599); Region: DUF3599; pfam12206
1034836006149	Putative Head-Tail Connector Protein Yqbg from Bacillus subtilis and similar proteins; Region: Yqbg; cd08053
1034836006150	Phage capsid family; Region: Phage_capsid; pfam05065
1034836006151	Bacteriophage capsid portal protein [General function prediction only]; Region: COG5518
1034836006152	Phage terminase large subunit [General function prediction only]; Region: XtmB; COG1783
1034836006153	Phage terminase small subunit; Region: Phage_terminase; pfam10668
1034836006154	Phage terminase, small subunit [DNA replication, recombination, and repair]; Region: XtmA; COG3728
1034836006155	positive control sigma-like factor; Validated; Region: PRK06930
1034836006156	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1034836006157	DNA binding residues [nucleotide binding]
1034836006158	hypothetical protein; Provisional; Region: PRK06921
1034836006159	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1034836006160	Walker A motif; other site
1034836006161	ATP binding site [chemical binding]; other site
1034836006162	Walker B motif; other site
1034836006163	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1034836006164	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1034836006165	non-specific DNA binding site [nucleotide binding]; other site
1034836006166	salt bridge; other site
1034836006167	sequence-specific DNA binding site [nucleotide binding]; other site
1034836006168	Domain of unknown function (DUF955); Region: DUF955; pfam06114
1034836006169	Protein of unknown function (DUF867); Region: DUF867; pfam05908
1034836006170	Pleckstrin homology (PH)-like domains in bacteria (PHb); Region: PH-like_bacteria; cd13225
1034836006171	pentamer interface [polypeptide binding]; other site
1034836006172	dodecaamer interface [polypeptide binding]; other site
1034836006173	N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: COG5632
1034836006174	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
1034836006175	amidase catalytic site [active]
1034836006176	Zn binding residues [ion binding]; other site
1034836006177	substrate binding site [chemical binding]; other site
1034836006178	FOG: LysM repeat [Cell envelope biogenesis, outer membrane]; Region: LytE; COG1388
1034836006179	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1034836006180	Putative peptidoglycan-binding domain-containing protein [Cell envelope biogenesis, outer membrane]; Region: COG3409
1034836006181	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
1034836006182	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1034836006183	binding surface
1034836006184	TPR motif; other site
1034836006185	Tetratricopeptide repeat; Region: TPR_12; pfam13424
1034836006186	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
1034836006187	binding surface
1034836006188	TPR motif; other site
1034836006189	DinB family; Region: DinB; cl17821
1034836006190	DinB superfamily; Region: DinB_2; pfam12867
1034836006191	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
1034836006192	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1034836006193	HAMP domain; Region: HAMP; pfam00672
1034836006194	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1034836006195	dimer interface [polypeptide binding]; other site
1034836006196	phosphorylation site [posttranslational modification]
1034836006197	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1034836006198	ATP binding site [chemical binding]; other site
1034836006199	Mg2+ binding site [ion binding]; other site
1034836006200	G-X-G motif; other site
1034836006201	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1034836006202	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1034836006203	active site
1034836006204	phosphorylation site [posttranslational modification]
1034836006205	intermolecular recognition site; other site
1034836006206	dimerization interface [polypeptide binding]; other site
1034836006207	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1034836006208	DNA binding site [nucleotide binding]
1034836006209	D-galactarate dehydratase / Altronate hydrolase, C terminus; Region: GD_AH_C; pfam04295
1034836006210	altronate oxidoreductase; Provisional; Region: PRK03643
1034836006211	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1034836006212	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1034836006213	DNA binding site [nucleotide binding]
1034836006214	domain linker motif; other site
1034836006215	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
1034836006216	dimerization interface [polypeptide binding]; other site
1034836006217	ligand binding site [chemical binding]; other site
1034836006218	Glucuronate isomerase; Region: UxaC; cl00829
1034836006219	Glucuronate isomerase [Carbohydrate transport and metabolism]; Region: UxaC; COG1904
1034836006220	NADH dehydrogenase, FAD-containing subunit [Energy production and conversion]; Region: Ndh; COG1252
1034836006221	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1034836006222	Uncharacterized conserved protein [Function unknown]; Region: COG2427
1034836006223	Uncharacterized protein containing double-stranded beta helix domain [Function unknown]; Region: COG4297
1034836006224	Multidrug resistance efflux transporter; Region: EmrE; pfam13536
1034836006225	phosphate ABC transporter ATP-binding protein; Provisional; Region: PRK14250
1034836006226	ATP-binding cassette domain of the phosphate transport system; Region: ABC_PstB_phosphate_transporter; cd03260
1034836006227	Walker A/P-loop; other site
1034836006228	ATP binding site [chemical binding]; other site
1034836006229	Q-loop/lid; other site
1034836006230	ABC transporter signature motif; other site
1034836006231	Walker B; other site
1034836006232	D-loop; other site
1034836006233	H-loop/switch region; other site
1034836006234	TIGR00245 family protein; Region: TIGR00245
1034836006235	uroporphyrinogen-III synthase; Reviewed; Region: hemD; PRK05928
1034836006236	Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in...; Region: HemD; cd06578
1034836006237	active site
1034836006238	This family includes the Gtfs, a group of homologous glycosyltransferases involved in the final stages of the biosynthesis of antibiotics vancomycin and related chloroeremomycin. Gtfs transfer sugar moieties from an activated NDP-sugar donor to the...; Region: GT1_Gtf_like; cd03784
1034836006239	glycosyltransferase, MGT family; Region: MGT; TIGR01426
1034836006240	active site
1034836006241	TDP-binding site; other site
1034836006242	acceptor substrate-binding pocket; other site
1034836006243	homodimer interface [polypeptide binding]; other site
1034836006244	Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]; Region: CypX; COG2124
1034836006245	Cytochrome P450; Region: p450; cl12078
1034836006246	Uncharacterized conserved protein [Function unknown]; Region: COG2427
1034836006247	Uncharacterized anaerobic dehydrogenase [General function prediction only]; Region: COG3383
1034836006248	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1034836006249	catalytic loop [active]
1034836006250	iron binding site [ion binding]; other site
1034836006251	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Region: NADH-G_4Fe-4S_3; smart00929
1034836006252	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1034836006253	Formate dehydrogenase H (Formate-Dh-H) catalyzes the reversible oxidation of formate to CO2 with the release of a proton and two electrons. It is a component of the anaerobic formate hydrogen lyase complex. The E. coli formate dehydrogenase H (Fdh-H) is...; Region: MopB_Formate-Dh-H; cd02753
1034836006254	[4Fe-4S] binding site [ion binding]; other site
1034836006255	molybdopterin cofactor binding site; other site
1034836006256	Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_CT_Formate-Dh-Na-like; cd02792
1034836006257	molybdopterin cofactor binding site; other site
1034836006258	Domain of unknown function (DUF4309); Region: DUF4309; pfam14172
1034836006259	Protein of unknown function (DUF2809); Region: DUF2809; pfam10990
1034836006260	Putative motility protein; Region: YjfB_motility; pfam14070
1034836006261	MgtC family; Region: MgtC; pfam02308
1034836006262	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1034836006263	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1034836006264	putative DNA binding site [nucleotide binding]; other site
1034836006265	putative Zn2+ binding site [ion binding]; other site
1034836006266	hypothetical protein; Provisional; Region: PRK09272
1034836006267	beta-phosphoglucomutase family hydrolase; Region: PGMB-YQAB-SF; TIGR02009
1034836006268	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1034836006269	motif II; other site
1034836006270	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1034836006271	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
1034836006272	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1034836006273	6-phospho-beta-galactosidase; Provisional; Region: PRK13511
1034836006274	beta-galactosidase; Region: BGL; TIGR03356
1034836006275	PTS_IIA, PTS system, lactose/cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_lac; cd00215
1034836006276	methionine cluster; other site
1034836006277	active site
1034836006278	phosphorylation site [posttranslational modification]
1034836006279	metal binding site [ion binding]; metal-binding site
1034836006280	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; cl17295
1034836006281	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
1034836006282	PTS_IIB_lactose: subunit IIB of enzyme II (EII) of the lactose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS) found in Firmicutes as well as Actinobacteria. In this system, EII is a lactose-specific permease with two...; Region: PTS_IIB_lactose; cd05565
1034836006283	active site
1034836006284	P-loop; other site
1034836006285	phosphorylation site [posttranslational modification]
1034836006286	galactose-1-phosphate uridylyltransferase; Provisional; Region: PRK05270
1034836006287	Glycosyl hydrolase family 53; Region: Glyco_hydro_53; cl06672
1034836006288	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1034836006289	putative Zn2+ binding site [ion binding]; other site
1034836006290	putative DNA binding site [nucleotide binding]; other site
1034836006291	dimerization interface [polypeptide binding]; other site
1034836006292	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1034836006293	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1034836006294	putative substrate translocation pore; other site
1034836006295	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1034836006296	Uncharacterized conserved protein [Function unknown]; Region: COG1359
1034836006297	Beta-lactamase class A [Defense mechanisms]; Region: PenP; COG2367
1034836006298	Beta-lactamase enzyme family; Region: Beta-lactamase2; pfam13354
1034836006299	Kelch motif; Region: Kelch_1; pfam01344
1034836006300	Kelch domain; Region: Kelch; smart00612
1034836006301	Kelch motif; Region: Kelch_1; pfam01344
1034836006302	Galactose oxidase, central domain; Region: Kelch_4; pfam13418
1034836006303	Kelch domain; Region: Kelch; smart00612
1034836006304	Bacillus cereus group antimicrobial protein; Region: lci; pfam12197
1034836006305	YolD-like protein; Region: YolD; pfam08863
1034836006306	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1034836006307	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
1034836006308	Coenzyme A binding pocket [chemical binding]; other site
1034836006309	SMI1 / KNR4 family (SUKH-1); Region: SMI1_KNR4; pfam09346
1034836006310	Ketopantoate reductase [Coenzyme metabolism]; Region: ApbA; COG1893
1034836006311	Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558
1034836006312	SMI1 / KNR4 family (SUKH-1); Region: SMI1_KNR4; pfam09346
1034836006313	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1034836006314	Bacterial EndoU nuclease; Region: EndoU_bacteria; pfam14436
1034836006315	LXG domain of WXG superfamily; Region: LXG; pfam04740
1034836006316	DNase/tRNase domain of colicin-like bacteriocin; Region: Colicin-DNase; pfam12639
1034836006317	SMI1 / KNR4 family (SUKH-1); Region: SMI1_KNR4; pfam09346
1034836006318	Helix-turn-helix domain; Region: HTH_17; pfam12728
1034836006319	Orthopoxvirus protein of unknown function (DUF830); Region: DUF830; cl13998
1034836006320	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
1034836006321	amidase catalytic site [active]
1034836006322	Zn binding residues [ion binding]; other site
1034836006323	substrate binding site [chemical binding]; other site
1034836006324	Bacterial SH3 domain; Region: SH3_3; cl17532
1034836006325	Putative peptidoglycan-binding domain-containing protein [Cell envelope biogenesis, outer membrane]; Region: COG3409
1034836006326	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
1034836006327	holin, SPP1 family; Region: holin_SPP1; TIGR01592
1034836006328	Haemolysin XhlA; Region: XhlA; pfam10779
1034836006329	Phage uncharacterized protein (Phage_XkdX); Region: Phage_XkdX; cl09900
1034836006330	Protein of unknown function (DUF2612); Region: DUF2612; pfam11041
1034836006331	Uncharacterized homolog of phage Mu protein gp47 [Function unknown]; Region: XkdT; COG3299
1034836006332	Protein of unknown function (DUF2634); Region: DUF2634; pfam10934
1034836006333	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1034836006334	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1034836006335	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1034836006336	catalytic residue [active]
1034836006337	cell division protein FtsE; Provisional; Region: PRK10908
1034836006338	Protein of unknown function (DUF3383); Region: DUF3383; pfam11863
1034836006339	Phage Mu protein F like protein; Region: Phage_Mu_F; cl10072
1034836006340	P22 coat protein - gene protein 5; Region: P22_CoatProtein; pfam11651
1034836006341	Uncharacterized conserved protein [Function unknown]; Region: COG1615; cl09133
1034836006342	Domain of unknown function (DUF4355); Region: DUF4355; pfam14265
1034836006343	Phage portal protein, SPP1 Gp6-like; Region: Phage_prot_Gp6; pfam05133
1034836006344	phage portal protein, SPP1 family; Region: portal_SPP1; TIGR01538
1034836006345	Phage terminase large subunit; Region: Terminase_3; cl12054
1034836006346	Terminase-like family; Region: Terminase_6; pfam03237
1034836006347	Uncharacterized conserved protein [Function unknown]; Region: COG5484
1034836006348	Helix-turn-helix domain; Region: HTH_28; pfam13518
1034836006349	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
1034836006350	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cl17315
1034836006351	homoserine O-acetyltransferase; Provisional; Region: PRK08775
1034836006352	Adenylate cyclase, family 3 (some proteins contain HAMP domain) [Signal transduction mechanisms]; Region: CyaA; COG2114
1034836006353	cyclase homology domain; Region: CHD; cd07302
1034836006354	nucleotidyl binding site; other site
1034836006355	metal binding site [ion binding]; metal-binding site
1034836006356	dimer interface [polypeptide binding]; other site
1034836006357	Adenine nucleotide alpha hydrolases superfamily including N type ATP PPases, ATP sulphurylases Universal Stress Response protein and electron transfer flavoprotein (ETF). The domain forms a apha/beta/apha fold which  binds to Adenosine nucleotide; Region: AANH_like; cl00292
1034836006358	Ligand Binding Site [chemical binding]; other site
1034836006359	Uncharacterized protein conserved in bacteria (DUF2225); Region: DUF2225; pfam09986
1034836006360	cell division protein ZipA; Provisional; Region: PRK01741
1034836006361	Holliday junction resolvase [DNA replication, recombination, and repair]; Region: Rus; COG4570
1034836006362	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
1034836006363	Walker A motif; other site
1034836006364	ATP binding site [chemical binding]; other site
1034836006365	Walker B motif; other site
1034836006366	arginine finger; other site
1034836006367	Replication initiation and membrane attachment; Region: DnaB_2; pfam07261
1034836006368	PDDEXK-like domain of unknown function (DUF3799); Region: DUF3799; pfam12684
1034836006369	Hypothetical protein Yqai; Region: Yqai; pfam09466
1034836006370	Helix-turn-helix XRE-family like proteins; Region: HTH_XRE; smart00530
1034836006371	Helix-turn-helix domain; Region: HTH_17; pfam12728
1034836006372	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1034836006373	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1034836006374	non-specific DNA binding site [nucleotide binding]; other site
1034836006375	salt bridge; other site
1034836006376	sequence-specific DNA binding site [nucleotide binding]; other site
1034836006377	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1034836006378	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1034836006379	non-specific DNA binding site [nucleotide binding]; other site
1034836006380	salt bridge; other site
1034836006381	sequence-specific DNA binding site [nucleotide binding]; other site
1034836006382	Staphylococcal nuclease homologues; Region: SNc; smart00318
1034836006383	Staphylococcal nuclease homologues. SNase homologues are found in bacteria, archaea, and eukaryotes. They contain no disufide bonds; Region: SNc; cd00175
1034836006384	Catalytic site; other site
1034836006385	Excalibur calcium-binding domain; Region: Excalibur; smart00894
1034836006386	Domain of unknown function (DUF955); Region: DUF955; pfam06114
1034836006387	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
1034836006388	phiLC3 phage and phage-related integrases, site-specific recombinases, DNA breaking-rejoining enzymes, C-terminal catalytic domain. This CD includes various bacterial (mainly gram positive) and phage integrases, including those similar to Lactococcus...; Region: INT_phiLC3_C; cd01189
1034836006389	Int/Topo IB signature motif; other site
1034836006390	cystathionine beta-lyase; Provisional; Region: PRK08064
1034836006391	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
1034836006392	homodimer interface [polypeptide binding]; other site
1034836006393	substrate-cofactor binding pocket; other site
1034836006394	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1034836006395	catalytic residue [active]
1034836006396	cystathionine gamma-synthase; Reviewed; Region: PRK08247
1034836006397	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
1034836006398	homodimer interface [polypeptide binding]; other site
1034836006399	substrate-cofactor binding pocket; other site
1034836006400	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1034836006401	catalytic residue [active]
1034836006402	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
1034836006403	Putative esterase; Region: Esterase; pfam00756
1034836006404	hypothetical protein; Provisional; Region: PRK13679
1034836006405	LigT like Phosphoesterase; Region: LigT_PEase; pfam02834
1034836006406	Acetyltransferase (GNAT) domain; Region: Acetyltransf_5; cl17496
1034836006407	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1034836006408	Coenzyme A binding pocket [chemical binding]; other site
1034836006409	Regulators of stationary/sporulation gene expression [Transcription]; Region: AbrB; COG2002
1034836006410	looped-hinge helix DNA binding domain, AbrB family; Region: lp_hng_hel_AbrB; TIGR01439
1034836006411	ABC-type Na+ transport system, ATPase component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatA; COG4555
1034836006412	ATP-binding cassette domain of the lipid transporters, subfamily A; Region: ABC_subfamily_A; cd03263
1034836006413	Walker A/P-loop; other site
1034836006414	ATP binding site [chemical binding]; other site
1034836006415	Q-loop/lid; other site
1034836006416	ABC transporter signature motif; other site
1034836006417	Walker B; other site
1034836006418	D-loop; other site
1034836006419	H-loop/switch region; other site
1034836006420	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
1034836006421	ABC-2 family transporter protein; Region: ABC2_membrane_3; pfam12698
1034836006422	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
1034836006423	Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair]; Region: UvrD; COG0210
1034836006424	Part of AAA domain; Region: AAA_19; pfam13245
1034836006425	Family description; Region: UvrD_C_2; pfam13538
1034836006426	Stage VI sporulation protein F; Region: SpoVIF; pfam14069
1034836006427	Protein of unknown function (DUF1360); Region: DUF1360; pfam07098
1034836006428	Spore Coat Protein X and V domain; Region: Coat_X; pfam07552
1034836006429	Spore Coat Protein X and V domain; Region: Coat_X; pfam07552
1034836006430	Spore Coat Protein X and V domain; Region: Coat_X; pfam07552
1034836006431	Spore coat protein Z; Region: Spore-coat_CotZ; pfam10612
1034836006432	Spore coat protein Z; Region: Spore-coat_CotZ; pfam10612
1034836006433	Spore coat protein CotO; Region: Spore_coat_CotO; pfam14153
1034836006434	enoyl-(acyl carrier protein) reductase; Provisional; Region: PRK08594
1034836006435	Enoyl acyl carrier protein (ACP) reductase (ENR), divergent SDR; Region: ENR_SDR; cd05372
1034836006436	NAD binding site [chemical binding]; other site
1034836006437	homotetramer interface [polypeptide binding]; other site
1034836006438	homodimer interface [polypeptide binding]; other site
1034836006439	substrate binding site [chemical binding]; other site
1034836006440	active site
1034836006441	4-amino-5-hydroxymethyl-2-methyl-pyrimidine phosphate kinase (HMPP-kinase) catalyzes two consecutive phosphorylation steps in the thiamine phosphate biosynthesis pathway, leading to the synthesis of vitamin B1. The first step is the phosphorylation of...; Region: HMPP_kinase; cd01169
1034836006442	dimer interface [polypeptide binding]; other site
1034836006443	substrate binding site [chemical binding]; other site
1034836006444	ATP binding site [chemical binding]; other site
1034836006445	thiamine/molybdopterin biosynthesis ThiF/MoeB-like protein; Validated; Region: PRK07688
1034836006446	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
1034836006447	ATP binding site [chemical binding]; other site
1034836006448	substrate interface [chemical binding]; other site
1034836006449	Thiazole synthase (ThiG) is the tetrameric enzyme that is involved in the formation of the thiazole moiety of thiamin pyrophosphate, an essential ubiquitous cofactor that plays an important role in carbohydrate and amino acid metabolism. ThiG catalyzes...; Region: ThiG; cd04728
1034836006450	ThiS interaction site; other site
1034836006451	putative active site [active]
1034836006452	tetramer interface [polypeptide binding]; other site
1034836006453	ThiaminS ubiquitin-like sulfur carrier protein; Region: ThiS; cd00565
1034836006454	thiS-thiF/thiG interaction site; other site
1034836006455	glycine oxidase ThiO; Region: thiamin_ThiO; TIGR02352
1034836006456	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1034836006457	Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-; Region: TMP_TenI; cd00564
1034836006458	thiamine phosphate binding site [chemical binding]; other site
1034836006459	active site
1034836006460	pyrophosphate binding site [ion binding]; other site
1034836006461	TENA/THI-4/PQQC family; Region: TENA_THI-4; cl15243
1034836006462	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; COG0475
1034836006463	Sodium/hydrogen exchanger family; Region: Na_H_Exchanger; pfam00999
1034836006464	K+ transport systems, NAD-binding component [Inorganic ion transport and metabolism]; Region: TrkA; COG0569
1034836006465	TrkA-N domain; Region: TrkA_N; pfam02254
1034836006466	TrkA-C domain; Region: TrkA_C; pfam02080
1034836006467	bis(5'-nucleosyl)-tetraphosphatase PrpE; Provisional; Region: PRK13625
1034836006468	Bacillus subtilis PrpE and related proteins, metallophosphatase domain; Region: MPP_PrpE; cd07423
1034836006469	active site
1034836006470	metal binding site [ion binding]; metal-binding site
1034836006471	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
1034836006472	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1034836006473	active site
1034836006474	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK04885
1034836006475	ATP-NAD kinase; Region: NAD_kinase; pfam01513
1034836006476	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
1034836006477	synthetase active site [active]
1034836006478	NTP binding site [chemical binding]; other site
1034836006479	metal binding site [ion binding]; metal-binding site
1034836006480	Uncharacterized subgroup 1 of the CYTH-like superfamily; Region: CYTH-like_Pase_1; cd07762
1034836006481	putative active site [active]
1034836006482	putative metal binding residues [ion binding]; other site
1034836006483	signature motif; other site
1034836006484	putative triphosphate binding site [ion binding]; other site
1034836006485	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
1034836006486	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1034836006487	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1034836006488	catalytic residue [active]
1034836006489	Truncated hemoglobins (trHbs) are a family of oxygen-binding heme proteins found in cyanobacteria, eubacteria, unicellular eukaryotes, and plants. The truncated hemoglobins have a characteristic two-over-two alpha helical folding pattern that is distinct...; Region: Trunc_globin; cd00454
1034836006490	apolar tunnel; other site
1034836006491	heme binding site [chemical binding]; other site
1034836006492	dimerization interface [polypeptide binding]; other site
1034836006493	Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]; Region: FrnE; COG2761
1034836006494	DsbA family, FrnE-like subfamily; composed of uncharacterized proteins containing a CXXC motif with similarity to DsbA and FrnE. FrnE is presumed to be a thiol oxidoreductase involved in polyketide biosynthesis, specifically in the production of the...; Region: DsbA_FrnE_like; cd03025
1034836006495	catalytic residues [active]
1034836006496	oligoendopeptidase F; Region: pepF; TIGR00181
1034836006497	Peptidase family M3B Oligopeptidase F (PepF); Region: M3B_PepF_3; cd09608
1034836006498	active site
1034836006499	Zn binding site [ion binding]; other site
1034836006500	Competence protein CoiA-like family; Region: CoiA; cl11541
1034836006501	adaptor protein; Provisional; Region: PRK02315
1034836006502	integral membrane protein, YjbE family; Region: R_switched_YjbE; TIGR03717
1034836006503	Arsenate Reductase (ArsC) family, Spx subfamily; Spx is a unique RNA polymerase (RNAP)-binding protein present in bacilli and some mollicutes. It inhibits transcription by binding to the C-terminal domain of the alpha subunit of RNAP, disrupting complex...; Region: ArsC_Spx; cd03032
1034836006504	ArsC family; Region: ArsC; pfam03960
1034836006505	putative catalytic residues [active]
1034836006506	thiol/disulfide switch; other site
1034836006507	Acetyltransferase (GNAT) domain; Region: Acetyltransf_7; pfam13508
1034836006508	Coenzyme A binding pocket [chemical binding]; other site
1034836006509	Putative glycosyl hydrolase domain; Region: DUF4015; pfam13200
1034836006510	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
1034836006511	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1034836006512	Walker A/P-loop; other site
1034836006513	ATP binding site [chemical binding]; other site
1034836006514	Q-loop/lid; other site
1034836006515	ABC transporter signature motif; other site
1034836006516	Walker B; other site
1034836006517	D-loop; other site
1034836006518	H-loop/switch region; other site
1034836006519	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
1034836006520	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppD; COG0444
1034836006521	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1034836006522	Walker A/P-loop; other site
1034836006523	ATP binding site [chemical binding]; other site
1034836006524	Q-loop/lid; other site
1034836006525	ABC transporter signature motif; other site
1034836006526	Walker B; other site
1034836006527	D-loop; other site
1034836006528	H-loop/switch region; other site
1034836006529	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1034836006530	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
1034836006531	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
1034836006532	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1034836006533	dimer interface [polypeptide binding]; other site
1034836006534	conserved gate region; other site
1034836006535	putative PBP binding loops; other site
1034836006536	ABC-ATPase subunit interface; other site
1034836006537	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
1034836006538	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1034836006539	dimer interface [polypeptide binding]; other site
1034836006540	conserved gate region; other site
1034836006541	putative PBP binding loops; other site
1034836006542	ABC-ATPase subunit interface; other site
1034836006543	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
1034836006544	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
1034836006545	peptide binding site [polypeptide binding]; other site
1034836006546	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
1034836006547	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
1034836006548	active site
1034836006549	HIGH motif; other site
1034836006550	dimer interface [polypeptide binding]; other site
1034836006551	KMSKS motif; other site
1034836006552	Protein of unknown function (DUF3603); Region: DUF3603; pfam12227
1034836006553	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
1034836006554	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
1034836006555	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1034836006556	dimer interface [polypeptide binding]; other site
1034836006557	conserved gate region; other site
1034836006558	putative PBP binding loops; other site
1034836006559	ABC-ATPase subunit interface; other site
1034836006560	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
1034836006561	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1034836006562	dimer interface [polypeptide binding]; other site
1034836006563	conserved gate region; other site
1034836006564	putative PBP binding loops; other site
1034836006565	ABC-ATPase subunit interface; other site
1034836006566	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
1034836006567	The substrate-binding component of the oligopeptide-binding protein, AppA, from Bacillus subtilis contains the type 2 periplasmic-binding fold; Region: PBP2_AppA_like; cd08514
1034836006568	peptide binding site [polypeptide binding]; other site
1034836006569	dipeptide transporter ATP-binding subunit; Provisional; Region: dppF; PRK11308
1034836006570	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1034836006571	Walker A/P-loop; other site
1034836006572	ATP binding site [chemical binding]; other site
1034836006573	Q-loop/lid; other site
1034836006574	ABC transporter signature motif; other site
1034836006575	Walker B; other site
1034836006576	D-loop; other site
1034836006577	H-loop/switch region; other site
1034836006578	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
1034836006579	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppD; COG0444
1034836006580	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1034836006581	Walker A/P-loop; other site
1034836006582	ATP binding site [chemical binding]; other site
1034836006583	Q-loop/lid; other site
1034836006584	ABC transporter signature motif; other site
1034836006585	Walker B; other site
1034836006586	D-loop; other site
1034836006587	H-loop/switch region; other site
1034836006588	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
1034836006589	Predicted Zn-dependent protease [Posttranslational modification, protein turnover, chaperones]; Region: COG5504
1034836006590	beta-ketoacyl-acyl-carrier-protein synthase II; Region: fabF; TIGR03150
1034836006591	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
1034836006592	dimer interface [polypeptide binding]; other site
1034836006593	active site
1034836006594	3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK09352
1034836006595	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
1034836006596	dimer interface [polypeptide binding]; other site
1034836006597	active site
1034836006598	CoA binding pocket [chemical binding]; other site
1034836006599	ComZ; Region: ComZ; pfam10815
1034836006600	Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein [General function prediction only]; Region: Med; COG1744
1034836006601	Periplasmic binding domain of the basic membrane lipoprotein Med in Bacillus and its close homologs from other bacteria and Archaea; Region: PBP1_BmpA_Med_like; cd06353
1034836006602	putative ligand binding site [chemical binding]; other site
1034836006603	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1034836006604	Lysophospholipase [Lipid metabolism]; Region: PldB; COG2267
1034836006605	Protein of unknown function (DUF2929); Region: DUF2929; pfam11151
1034836006606	YjzC-like protein; Region: YjzC; pfam14168
1034836006607	ornithine carbamoyltransferase; Provisional; Region: PRK00779
1034836006608	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
1034836006609	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
1034836006610	carbamoyl phosphate synthase large subunit; Reviewed; Region: carB; PRK12815
1034836006611	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1034836006612	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
1034836006613	Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; pfam02787
1034836006614	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1034836006615	ATP-grasp domain; Region: ATP-grasp_4; cl17255
1034836006616	carbamoyl phosphate synthase small subunit; Reviewed; Region: PRK12838
1034836006617	Carbamoyl-phosphate synthase small chain, CPSase domain; Region: CPSase_sm_chain; pfam00988
1034836006618	Small chain of the glutamine-dependent form of carbamoyl phosphate synthase, CPSase II; Region: GATase1_CPSase; cd01744
1034836006619	catalytic site [active]
1034836006620	subunit interface [polypeptide binding]; other site
1034836006621	acetylornithine aminotransferase; Provisional; Region: argD; PRK02936
1034836006622	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1034836006623	inhibitor-cofactor binding pocket; inhibition site
1034836006624	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1034836006625	catalytic residue [active]
1034836006626	AAK_NAGK-like: N-Acetyl-L-glutamate kinase (NAGK)-like . Included in this CD are the Escherichia coli and Pseudomonas aeruginosa type NAGKs which catalyze the phosphorylation of N-acetyl-L-glutamate (NAG) by ATP in the second step of arginine...; Region: AAK_NAGK-like; cd04238
1034836006627	nucleotide binding site [chemical binding]; other site
1034836006628	N-acetyl-L-glutamate binding site [chemical binding]; other site
1034836006629	Ornithine acetyltransferase (OAT) family; also referred to as ArgJ. OAT catalyzes the first and fifth steps in arginine biosynthesis, coupling acetylation of glutamate with deacetylation of N-acetylornithine, which allows recycling of the acetyl group in...; Region: OAT; cd02152
1034836006630	heterotetramer interface [polypeptide binding]; other site
1034836006631	active site pocket [active]
1034836006632	cleavage site
1034836006633	N-acetyl-gamma-glutamyl-phosphate reductase; Validated; Region: argC; PRK00436
1034836006634	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
1034836006635	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1034836006636	FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277
1034836006637	D-arabinono-1,4-lactone oxidase; Region: ALO; pfam04030
1034836006638	Phosphopentomutase [Carbohydrate transport and metabolism]; Region: DeoB; cl17415
1034836006639	site-specific tyrosine recombinase XerD; Reviewed; Region: xerD; PRK00283
1034836006640	XerD and XerC integrases, DNA breaking-rejoining enzymes, N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination...; Region: INT_XerDC; cd00798
1034836006641	active site
1034836006642	Int/Topo IB signature motif; other site
1034836006643	Protein of unknown function (DUF4227); Region: DUF4227; pfam14004
1034836006644	ferric uptake regulator; Provisional; Region: fur; PRK09462
1034836006645	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
1034836006646	metal binding site 2 [ion binding]; metal-binding site
1034836006647	putative DNA binding helix; other site
1034836006648	metal binding site 1 [ion binding]; metal-binding site
1034836006649	dimer interface [polypeptide binding]; other site
1034836006650	structural Zn2+ binding site [ion binding]; other site
1034836006651	stage II sporulation protein M; Region: spo_II_M; TIGR02831
1034836006652	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
1034836006653	Malic enzyme [Energy production and conversion]; Region: SfcA; COG0281
1034836006654	Malic enzyme, N-terminal domain; Region: malic; pfam00390
1034836006655	Malic enzyme, NAD binding domain; Region: Malic_M; smart00919
1034836006656	NAD(P) binding pocket [chemical binding]; other site
1034836006657	Na+/H+ antiporter NhaC; Region: antiport_nhaC; TIGR00931
1034836006658	aspartate ammonia-lyase; Provisional; Region: aspA; PRK12273
1034836006659	Aspartase; Region: Aspartase; cd01357
1034836006660	active sites [active]
1034836006661	tetramer interface [polypeptide binding]; other site
1034836006662	Type I (cytosolic) bacterial L-asparaginase; Region: L-asparaginase_I; cd08963
1034836006663	active site
1034836006664	homodimer interface [polypeptide binding]; other site
1034836006665	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1034836006666	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1034836006667	non-specific DNA binding site [nucleotide binding]; other site
1034836006668	salt bridge; other site
1034836006669	sequence-specific DNA binding site [nucleotide binding]; other site
1034836006670	TIGR00375 family protein; Region: TIGR00375
1034836006671	PHP-associated; Region: PHP_C; pfam13263
1034836006672	zinc-ribbon domain; Region: zinc_ribbon_2; pfam13240
1034836006673	nudix-type nucleoside diphosphatase, YffH/AdpP family; Region: TIGR00052
1034836006674	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
1034836006675	dimer interface [polypeptide binding]; other site
1034836006676	ADP-ribose binding site [chemical binding]; other site
1034836006677	active site
1034836006678	nudix motif; other site
1034836006679	metal binding site [ion binding]; metal-binding site
1034836006680	Protein of unknown function (DUF3936); Region: DUF3936; pfam13072
1034836006681	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1034836006682	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1034836006683	active site
1034836006684	catalytic tetrad [active]
1034836006685	Hydrolases of the alpha/beta superfamily [General function prediction only]; Region: COG1073
1034836006686	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
1034836006687	BAAT / Acyl-CoA thioester hydrolase C terminal; Region: BAAT_C; pfam08840
1034836006688	Eukaryotic protein of unknown function (DUF829); Region: DUF829; pfam05705
1034836006689	Protein of unknown function (DUF2552); Region: DUF2552; pfam10827
1034836006690	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4918
1034836006691	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
1034836006692	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1034836006693	Coenzyme A binding pocket [chemical binding]; other site
1034836006694	Uncharacterized protein family (UPF0157); Region: UPF0157; pfam04229
1034836006695	Sortase and related acyltransferases [Cell envelope biogenesis, outer membrane]; Region: COG1247
1034836006696	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1034836006697	Coenzyme A binding pocket [chemical binding]; other site
1034836006698	DNA polymerase IV; Reviewed; Region: PRK03103
1034836006699	umuC subunit of DNA Polymerase V; Region: PolY_Pol_V_umuC; cd01700
1034836006700	active site
1034836006701	DNA binding site [nucleotide binding]
1034836006702	Domain of unknown function (DUF4113); Region: DUF4113; pfam13438
1034836006703	YolD-like protein; Region: YolD; pfam08863
1034836006704	YqzH-like protein; Region: YqzH; pfam14164
1034836006705	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
1034836006706	Domain of unknown function DUF20; Region: UPF0118; pfam01594
1034836006707	pantothenate kinase; Provisional; Region: PRK05439
1034836006708	Pantothenate kinase (PanK) catalyzes the phosphorylation of pantothenic acid to form 4'-phosphopantothenic, which is the first of five steps in coenzyme A (CoA) biosynthetic pathway. The reaction carried out by this enzyme is a key regulatory point...; Region: PanK; cd02025
1034836006709	ATP-binding site [chemical binding]; other site
1034836006710	CoA-binding site [chemical binding]; other site
1034836006711	Mg2+-binding site [ion binding]; other site
1034836006712	D-serine dehydratase; Provisional; Region: PRK02991
1034836006713	Pyridoxal-phosphate dependent enzyme; Region: PALP; pfam00291
1034836006714	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1034836006715	catalytic residue [active]
1034836006716	Short-chain dehydrogenases of various substrate specificities [General function prediction only]; Region: DltE; COG0300
1034836006717	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1034836006718	NAD(P) binding site [chemical binding]; other site
1034836006719	active site
1034836006720	Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491
1034836006721	NADP oxidoreductase coenzyme F420-dependent; Region: F420_oxidored; cl17232
1034836006722	Pyrroline-5-carboxylate reductase [Amino acid transport and metabolism]; Region: ProC; COG0345
1034836006723	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1034836006724	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1034836006725	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1034836006726	dimerization interface [polypeptide binding]; other site
1034836006727	GlpM protein; Region: GlpM; cl01212
1034836006728	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
1034836006729	Old yellow enzyme (OYE) YqjM-like FMN binding domain. YqjM is involved in the oxidative stress response of Bacillus subtilis.  Like the other OYE members, each monomer of YqjM contains FMN as a non-covalently bound cofactor and uses NADPH as a reducing...; Region: OYE_YqiM_FMN; cd02932
1034836006730	active site
1034836006731	FMN binding site [chemical binding]; other site
1034836006732	substrate binding site [chemical binding]; other site
1034836006733	homotetramer interface [polypeptide binding]; other site
1034836006734	catalytic residue [active]
1034836006735	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
1034836006736	ribonuclease Z; Region: RNase_Z; TIGR02651
1034836006737	glucose-6-phosphate 1-dehydrogenase; Validated; Region: PRK05722
1034836006738	Glucose-6-phosphate dehydrogenase, NAD binding domain; Region: G6PD_N; pfam00479
1034836006739	Glucose-6-phosphate dehydrogenase, C-terminal domain; Region: G6PD_C; pfam02781
1034836006740	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
1034836006741	6-phosphogluconate dehydrogenase; Validated; Region: PRK09287
1034836006742	6-phosphogluconate dehydrogenase, C-terminal domain; Region: 6PGD; pfam00393
1034836006743	DNA polymerase IV; Validated; Region: PRK01810
1034836006744	DNA Polymerase IV/Kappa; Region: PolY_Pol_IV_kappa; cd03586
1034836006745	active site
1034836006746	DNA binding site [nucleotide binding]
1034836006747	Domain of unknown function (DUF4113); Region: DUF4113; pfam13438
1034836006748	OxaA-like protein precursor; Validated; Region: PRK01622
1034836006749	Preprotein translocase subunit YidC [Intracellular trafficking and secretion]; Region: YidC; COG0706
1034836006750	potential frameshift: common BLAST hit: gi|154686652|ref|YP_001421813.1| YqjE
1034836006751	Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) [Lipid metabolism]; Region: COG4799
1034836006752	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682
1034836006753	Acetyl-CoA carboxylase alpha subunit [Lipid metabolism]; Region: AccA; cl17345
1034836006754	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1034836006755	Methylmalonyl-CoA epimerase (MMCE); Region: MMCE; cd07249
1034836006756	dimer interface [polypeptide binding]; other site
1034836006757	substrate binding site [chemical binding]; other site
1034836006758	metal binding site [ion binding]; metal-binding site
1034836006759	Uncharacterized protein conserved in bacteria [Function unknown]; Region: ErfK; COG1376
1034836006760	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
1034836006761	Predicted membrane protein [Function unknown]; Region: COG4129
1034836006762	Bacterial protein of unknown function (DUF939); Region: DUF939; pfam06081
1034836006763	DUF939 C-terminal domain; Region: DUF939_C; pfam11728
1034836006764	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
1034836006765	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1034836006766	Walker A/P-loop; other site
1034836006767	ATP binding site [chemical binding]; other site
1034836006768	Q-loop/lid; other site
1034836006769	ABC transporter signature motif; other site
1034836006770	Walker B; other site
1034836006771	D-loop; other site
1034836006772	H-loop/switch region; other site
1034836006773	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1034836006774	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1034836006775	dimer interface [polypeptide binding]; other site
1034836006776	conserved gate region; other site
1034836006777	putative PBP binding loops; other site
1034836006778	ABC-ATPase subunit interface; other site
1034836006779	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1034836006780	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
1034836006781	substrate binding pocket [chemical binding]; other site
1034836006782	membrane-bound complex binding site; other site
1034836006783	hinge residues; other site
1034836006784	Disulphide isomerase; Region: Disulph_isomer; pfam06491
1034836006785	lipid kinase, YegS/Rv2252/BmrU family; Region: TIGR00147
1034836006786	Diacylglycerol kinase catalytic domain; Region: DAGK_cat; pfam00781
1034836006787	branched-chain alpha-keto acid dehydrogenase subunit E2; Reviewed; Region: PRK11856
1034836006788	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1034836006789	E3 interaction surface; other site
1034836006790	lipoyl attachment site [posttranslational modification]; other site
1034836006791	e3 binding domain; Region: E3_binding; pfam02817
1034836006792	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
1034836006793	Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit [Energy production and conversion]; Region: AcoB; COG0022
1034836006794	Pyrimidine (PYR) binding domain of the beta subunits of the E1 components of human pyruvate dehydrogenase complex (E1- PDHc) and related proteins; Region: TPP_PYR_E1-PDHc-beta_like; cd07036
1034836006795	alpha subunit interface [polypeptide binding]; other site
1034836006796	TPP binding site [chemical binding]; other site
1034836006797	heterodimer interface [polypeptide binding]; other site
1034836006798	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1034836006799	Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit [Energy production and conversion]; Region: AcoA; COG1071
1034836006800	Thiamine pyrophosphate (TPP) family, E1 of PDC_ADC_BCADC subfamily, TPP-binding module; composed of proteins similar to the E1 components of the human pyruvate dehydrogenase complex (PDC), the acetoin dehydrogenase complex (ADC) and the branched chain...; Region: TPP_E1_PDC_ADC_BCADC; cd02000
1034836006801	tetramer interface [polypeptide binding]; other site
1034836006802	TPP-binding site [chemical binding]; other site
1034836006803	heterodimer interface [polypeptide binding]; other site
1034836006804	phosphorylation loop region [posttranslational modification]
1034836006805	dihydrolipoamide dehydrogenase; Validated; Region: PRK05976
1034836006806	Anaerobic glycerol-3-phosphate dehydrogenase [Amino acid transport and metabolism]; Region: GlpB; cl17730
1034836006807	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1034836006808	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
1034836006809	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1034836006810	nucleotide binding site [chemical binding]; other site
1034836006811	Acetokinase family; Region: Acetate_kinase; cl17229
1034836006812	Glutamate dehydrogenase/leucine dehydrogenase [Amino acid transport and metabolism]; Region: GdhA; COG0334
1034836006813	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
1034836006814	NAD(P) binding domain of leucine dehydrogenase, phenylalanine dehydrogenase, and valine dehydrogenase; Region: NAD_bind_Leu_Phe_Val_DH; cd01075
1034836006815	NAD binding site [chemical binding]; other site
1034836006816	Phe binding site; other site
1034836006817	phosphate butyryltransferase; Validated; Region: PRK07742
1034836006818	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1034836006819	Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains [Transcription / Signal transduction mechanisms]; Region: RocR; COG3829
1034836006820	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1034836006821	putative active site [active]
1034836006822	heme pocket [chemical binding]; other site
1034836006823	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1034836006824	putative active site [active]
1034836006825	heme pocket [chemical binding]; other site
1034836006826	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1034836006827	Walker A motif; other site
1034836006828	ATP binding site [chemical binding]; other site
1034836006829	Walker B motif; other site
1034836006830	arginine finger; other site
1034836006831	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
1034836006832	Protein of unknown function (DUF2627); Region: DUF2627; pfam11118
1034836006833	Phosphoenolpyruvate phosphomutase; Region: PEP_mutase; pfam13714
1034836006834	Members of the ICL/PEPM enzyme family catalyze either P-C or C-C bond formation/cleavage. Known members are phosphoenolpyruvate mutase (PEPM), phosphonopyruvate hydrolase (PPH), carboxyPEP mutase (CPEP mutase), oxaloacetate hydrolase (OAH), isocitrate...; Region: ICL_PEPM; cd00377
1034836006835	tetramer interface [polypeptide binding]; other site
1034836006836	active site
1034836006837	Mg2+/Mn2+ binding site [ion binding]; other site
1034836006838	2-methylcitrate dehydratase; Provisional; Region: prpD; PRK09425
1034836006839	2-methylcitrate dehydratase; Region: prpD; TIGR02330
1034836006840	Citrate synthase (CS) catalyzes the condensation of acetyl coenzyme A (AcCoA) and oxalacetate (OAA) to form citrate and coenzyme A (CoA), the first step in the oxidative citric acid cycle (TCA or Krebs cycle). Peroxisomal CS is involved in the glyoxylate...; Region: citrate_synt_like_1; cd06118
1034836006841	dimer interface [polypeptide binding]; other site
1034836006842	Citrate synthase; Region: Citrate_synt; pfam00285
1034836006843	active site
1034836006844	coenzyme A binding site [chemical binding]; other site
1034836006845	citrylCoA binding site [chemical binding]; other site
1034836006846	oxalacetate/citrate binding site [chemical binding]; other site
1034836006847	catalytic triad [active]
1034836006848	Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960
1034836006849	Short chain acyl-CoA dehydrogenases and eukaryotic short/branched chain acyl-CoA dehydrogenases; Region: SCAD_SBCAD; cd01158
1034836006850	FAD binding site [chemical binding]; other site
1034836006851	homotetramer interface [polypeptide binding]; other site
1034836006852	substrate binding pocket [chemical binding]; other site
1034836006853	catalytic base [active]
1034836006854	3-hydroxybutyryl-CoA dehydrogenase; Validated; Region: PRK05808
1034836006855	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
1034836006856	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
1034836006857	acetyl-CoA acetyltransferase; Provisional; Region: PRK08235
1034836006858	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
1034836006859	dimer interface [polypeptide binding]; other site
1034836006860	active site
1034836006861	Glycerophosphoryl diester phosphodiesterase [Energy production and conversion]; Region: UgpQ; COG0584
1034836006862	Glycerophosphodiester phosphodiesterase domain of Thermoanaerobacter tengcongensis and similar proteins; Region: GDPD_TtGDE_like; cd08563
1034836006863	active site
1034836006864	catalytic site [active]
1034836006865	metal binding site [ion binding]; metal-binding site
1034836006866	dimer interface [polypeptide binding]; other site
1034836006867	N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: AmiC; COG0860
1034836006868	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
1034836006869	active site
1034836006870	metal binding site [ion binding]; metal-binding site
1034836006871	putative sporulation protein YtaF; Region: spore_YtaF; TIGR02840
1034836006872	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1034836006873	sequence-specific DNA binding site [nucleotide binding]; other site
1034836006874	salt bridge; other site
1034836006875	Protein of unknown function (DUF1232); Region: DUF1232; pfam06803
1034836006876	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
1034836006877	Old yellow enzyme (OYE)-related FMN binding domain, group 4.  Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a reducing agent with oxygens, quinones, and alpha,beta-unsaturated aldehydes and ketones, and can act as...; Region: OYE_like_4_FMN; cd04735
1034836006878	putative active site [active]
1034836006879	putative FMN binding site [chemical binding]; other site
1034836006880	putative substrate binding site [chemical binding]; other site
1034836006881	putative catalytic residue [active]
1034836006882	Spore germination protein gerPA/gerPF; Region: gerPA; pfam10676
1034836006883	Spore germination protein gerPA/gerPF; Region: gerPA; pfam10676
1034836006884	alanine racemase; Region: alr; TIGR00492
1034836006885	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Alanine Racemase; Region: PLPDE_III_AR; cd00430
1034836006886	active site
1034836006887	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1034836006888	dimer interface [polypeptide binding]; other site
1034836006889	substrate binding site [chemical binding]; other site
1034836006890	catalytic residues [active]
1034836006891	sporulation transcription factor Spo0A; Region: spore_0_A; TIGR02875
1034836006892	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1034836006893	active site
1034836006894	phosphorylation site [posttranslational modification]
1034836006895	intermolecular recognition site; other site
1034836006896	dimerization interface [polypeptide binding]; other site
1034836006897	Sporulation initiation factor Spo0A C terminal; Region: Spo0A_C; pfam08769
1034836006898	stage IV sporulation protein B; Region: spore_IV_B; TIGR02860
1034836006899	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
1034836006900	protein binding site [polypeptide binding]; other site
1034836006901	SpoIVB peptidase S55; Region: Peptidase_S55; pfam05580
1034836006902	ATPase involved in DNA repair [DNA replication, recombination, and repair]; Region: RecN; COG0497
1034836006903	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
1034836006904	Walker A/P-loop; other site
1034836006905	ATP binding site [chemical binding]; other site
1034836006906	Q-loop/lid; other site
1034836006907	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
1034836006908	ABC transporter signature motif; other site
1034836006909	Walker B; other site
1034836006910	D-loop; other site
1034836006911	H-loop/switch region; other site
1034836006912	Arginine repressor, DNA binding domain; Region: Arg_repressor; pfam01316
1034836006913	arginine repressor; Provisional; Region: PRK04280
1034836006914	Arginine repressor, C-terminal domain; Region: Arg_repressor_C; pfam02863
1034836006915	Predicted rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: COG1189
1034836006916	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1034836006917	RNA binding surface [nucleotide binding]; other site
1034836006918	FtsJ-like methyltransferase; Region: FtsJ; pfam01728
1034836006919	1-deoxy-D-xylulose-5-phosphate synthase; Region: dxs; TIGR00204
1034836006920	Thiamine pyrophosphate (TPP) family, DXS subfamily, TPP-binding module; 1-Deoxy-D-xylulose-5-phosphate synthase (DXS) is a regulatory enzyme of the mevalonate-independent pathway involved in terpenoid biosynthesis. Terpeniods are plant natural products...; Region: TPP_DXS; cd02007
1034836006921	TPP-binding site; other site
1034836006922	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
1034836006923	PYR/PP interface [polypeptide binding]; other site
1034836006924	dimer interface [polypeptide binding]; other site
1034836006925	TPP binding site [chemical binding]; other site
1034836006926	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1034836006927	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
1034836006928	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
1034836006929	substrate binding pocket [chemical binding]; other site
1034836006930	chain length determination region; other site
1034836006931	substrate-Mg2+ binding site; other site
1034836006932	catalytic residues [active]
1034836006933	aspartate-rich region 1; other site
1034836006934	active site lid residues [active]
1034836006935	aspartate-rich region 2; other site
1034836006936	exodeoxyribonuclease VII small subunit; Provisional; Region: PRK14063
1034836006937	exodeoxyribonuclease VII, large subunit; Region: xseA; TIGR00237
1034836006938	ExoVII_LU_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold domain of Escherichia coli exodeoxyribonuclease VII (ExoVII) large subunit. E. coli ExoVII is composed of two non-identical subunits. E. coli ExoVII is a...; Region: ExoVII_LU_OBF; cd04489
1034836006939	generic binding surface II; other site
1034836006940	generic binding surface I; other site
1034836006941	Tubulin/FtsZ: Family includes tubulin alpha-, beta-, gamma-, delta-, and epsilon-tubulins as well as FtsZ, all of which are involved in polymer formation. Tubulin is the major component of microtubules, but also exists as a heterodimer and as a curved...; Region: Tubulin_FtsZ; cl10017
1034836006942	bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase; Provisional; Region: PRK14190
1034836006943	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763
1034836006944	NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080
1034836006945	homodimer interface [polypeptide binding]; other site
1034836006946	NADP binding site [chemical binding]; other site
1034836006947	substrate binding site [chemical binding]; other site
1034836006948	Transcription termination factor NusB (N protein-Utilization Substance B). NusB plays a key role in the regulation of ribosomal RNA biosynthesis in eubacteria by modulating the efficiency of transcriptional antitermination. NusB along with other Nus...; Region: Terminator_NusB; cd00619
1034836006949	putative RNA binding site [nucleotide binding]; other site
1034836006950	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1302
1034836006951	acetyl-CoA carboxylase biotin carboxylase subunit; Validated; Region: PRK08591
1034836006952	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1034836006953	ATP-grasp domain; Region: ATP-grasp_4; cl17255
1034836006954	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
1034836006955	acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated; Region: PRK06302
1034836006956	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
1034836006957	carboxyltransferase (CT) interaction site; other site
1034836006958	biotinylation site [posttranslational modification]; other site
1034836006959	SpoIIIAH-like protein; Region: SpoIIIAH; pfam12685
1034836006960	stage III sporulation protein AG; Region: spore_III_AG; TIGR02830
1034836006961	Stage III sporulation protein AF (Spore_III_AF); Region: Spore_III_AF; pfam09581
1034836006962	stage III sporulation protein AE; Region: spore_III_AE; TIGR02829
1034836006963	stage III sporulation protein AD; Region: spore_III_AD; TIGR02849
1034836006964	stage III sporulation protein AC; Region: spore_III_AC; TIGR02848
1034836006965	stage III sporulation protein SpoAB; Provisional; Region: PRK08307
1034836006966	stage III sporulation protein AA; Region: spore_III_AA; TIGR02858
1034836006967	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1034836006968	Walker A motif; other site
1034836006969	ATP binding site [chemical binding]; other site
1034836006970	Walker B motif; other site
1034836006971	Protein of unknown function (DUF2619); Region: DUF2619; pfam10942
1034836006972	elongation factor P; Validated; Region: PRK00529
1034836006973	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
1034836006974	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
1034836006975	RNA binding site [nucleotide binding]; other site
1034836006976	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
1034836006977	RNA binding site [nucleotide binding]; other site
1034836006978	Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006
1034836006979	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
1034836006980	Similar to Prolidase and Aminopeptidase P. The members of this subfamily presumably catalyse hydrolysis of Xaa-Pro dipeptides and/or release of any N-terminal amino acid, including proline, that is linked with proline; Region: APP-like; cd01092
1034836006981	active site
1034836006982	Conserved membrane protein YqhR; Region: YqhR; pfam11085
1034836006983	Predicted metal-dependent enzyme [General function prediction only]; Region: COG3872
1034836006984	Domain of unknown function (DUF1772); Region: DUF1772; cl12097
1034836006985	Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; Region: RssA; COG1752
1034836006986	ExoU and VipD-like proteins; homologus to patatin, cPLA2, and iPLA2; Region: Pat_ExoU_VipD_like; cd07207
1034836006987	active site
1034836006988	nucleophile elbow; other site
1034836006989	manganese transport transcriptional regulator; Provisional; Region: PRK03902
1034836006990	Iron dependent repressor, N-terminal DNA binding domain; Region: Fe_dep_repress; pfam01325
1034836006991	Iron dependent repressor, metal binding and dimerisation domain; Region: Fe_dep_repr_C; pfam02742
1034836006992	Lipoate-protein ligase A [Coenzyme metabolism]; Region: LplA; COG0095
1034836006993	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
1034836006994	active site residue [active]
1034836006995	Glycine cleavage system protein P (pyridoxal-binding), N-terminal domain [Amino acid transport and metabolism]; Region: GcvP; COG0403
1034836006996	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
1034836006997	tetramer interface [polypeptide binding]; other site
1034836006998	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1034836006999	catalytic residue [active]
1034836007000	Glycine cleavage system protein P (pyridoxal-binding), N-terminal domain [Amino acid transport and metabolism]; Region: GcvP; COG0403
1034836007001	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
1034836007002	tetramer interface [polypeptide binding]; other site
1034836007003	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1034836007004	catalytic residue [active]
1034836007005	glycine cleavage system aminomethyltransferase T; Reviewed; Region: gcvT; PRK00389
1034836007006	Sarcosine oxidase, gamma subunit family; Region: SoxG; cl01893
1034836007007	Glycine cleavage T-protein C-terminal barrel domain; Region: GCV_T_C; pfam08669
1034836007008	SNF2 family N-terminal domain; Region: SNF2_N; pfam00176
1034836007009	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1034836007010	ATP binding site [chemical binding]; other site
1034836007011	putative Mg++ binding site [ion binding]; other site
1034836007012	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1034836007013	nucleotide binding region [chemical binding]; other site
1034836007014	ATP-binding site [chemical binding]; other site
1034836007015	Bacterial protein YqhG of unknown function; Region: YqhG; pfam11079
1034836007016	DNA polymerase III, epsilon subunit, Proteobacterial; Region: dnaQ_proteo; TIGR01406
1034836007017	Anti-repressor SinI; Region: SinI; pfam08671
1034836007018	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1034836007019	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1034836007020	non-specific DNA binding site [nucleotide binding]; other site
1034836007021	salt bridge; other site
1034836007022	sequence-specific DNA binding site [nucleotide binding]; other site
1034836007023	Anti-repressor SinI; Region: SinI; pfam08671
1034836007024	Camelysin metallo-endopeptidase; Region: Peptidase_M73; cl13780
1034836007025	Signal peptidase I [Intracellular trafficking and secretion]; Region: LepB; COG0681
1034836007026	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
1034836007027	Catalytic site [active]
1034836007028	YqxM protein; Region: YqxM_for_SipW; TIGR04087
1034836007029	Protein of unknown function (DUF3889); Region: DUF3889; pfam13028
1034836007030	YqzE-like protein; Region: YqzE; pfam14038
1034836007031	ComG operon protein 7; Region: ComGG; pfam14173
1034836007032	Competence protein ComGF [Intracellular trafficking and secretion]; Region: ComGF; COG4940
1034836007033	Competence protein ComGC [Intracellular trafficking and secretion]; Region: ComGC; COG4537
1034836007034	Type II secretory pathway, component PulF [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulF; COG1459
1034836007035	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
1034836007036	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
1034836007037	Type II/IV secretion system protein; Region: T2SE; pfam00437
1034836007038	PulE/GspE The type II secretory pathway is the main terminal branch of the general secretory pathway (GSP). It is responsible for the export the majority of Gram-negative bacterial exoenzymes and toxins. PulE is a cytoplasmic protein of the GSP, which...; Region: PulE-GspE; cd01129
1034836007039	Walker A motif; other site
1034836007040	ATP binding site [chemical binding]; other site
1034836007041	Walker B motif; other site
1034836007042	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
1034836007043	Escherichia coli CorA-Salmonella typhimurium ZntB_like family; Region: EcCorA_ZntB-like; cd12821
1034836007044	Cl binding site [ion binding]; other site
1034836007045	oligomer interface [polypeptide binding]; other site
1034836007046	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
1034836007047	Domain of unknown function DUF21; Region: DUF21; pfam01595
1034836007048	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1034836007049	Transporter associated domain; Region: CorC_HlyC; smart01091
1034836007050	Sulphate Transporter and Anti-Sigma factor antagonist domain of the "stressosome" complex proteins RsbS and RsbR, regulators of the bacterial stress activated alternative sigma factor sigma-B by phosphorylation; Region: STAS_RsbR_RsbS_like; cd07041
1034836007051	Arsenate Reductase (ArsC) family, Spx subfamily; Spx is a unique RNA polymerase (RNAP)-binding protein present in bacilli and some mollicutes. It inhibits transcription by binding to the C-terminal domain of the alpha subunit of RNAP, disrupting complex...; Region: ArsC_Spx; cd03032
1034836007052	ArsC family; Region: ArsC; pfam03960
1034836007053	putative catalytic residues [active]
1034836007054	thiol/disulfide switch; other site
1034836007055	Protein of unknown function (DUF2626); Region: DUF2626; pfam11117
1034836007056	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
1034836007057	Protein of unknown function (DUF2759); Region: DUF2759; pfam10958
1034836007058	Uncharacterized conserved protein [Function unknown]; Region: COG0011
1034836007059	potential frameshift: common BLAST hit: gi|154686745|ref|YP_001421906.1| YqgU
1034836007060	Predicted carboxypeptidase [Amino acid transport and metabolism]; Region: COG2866
1034836007061	Peptidase M14 carboxypeptidase family-like domain of Endopeptidase I; Region: M14_Endopeptidase_I; cd06229
1034836007062	putative active site [active]
1034836007063	Zn binding site [ion binding]; other site
1034836007064	ROK family protein (putative glucokinase); Region: ROK_glcA_fam; TIGR00744
1034836007065	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1034836007066	nucleotide binding site [chemical binding]; other site
1034836007067	Bacterial protein of unknown function (DUF910); Region: DUF910; pfam06014
1034836007068	Na+/H+ antiporter NhaC; Region: antiport_nhaC; TIGR00931
1034836007069	H+/citrate symporter [Energy production and conversion]; Region: CitM; cl17620
1034836007070	5-formyltetrahydrofolate cyclo-ligase family; Region: 5-FTHF_cyc-lig; pfam01812
1034836007071	5,10-methenyltetrahydrofolate synthetase; Region: MTHFS_bact; TIGR02727
1034836007072	YceG-like family; Region: YceG; pfam02618
1034836007073	phosphate ABC transporter ATP-binding protein; Provisional; Region: PRK14274
1034836007074	ATP-binding cassette domain of the phosphate transport system; Region: ABC_PstB_phosphate_transporter; cd03260
1034836007075	Walker A/P-loop; other site
1034836007076	ATP binding site [chemical binding]; other site
1034836007077	Q-loop/lid; other site
1034836007078	ABC transporter signature motif; other site
1034836007079	Walker B; other site
1034836007080	D-loop; other site
1034836007081	H-loop/switch region; other site
1034836007082	phosphate ABC transporter ATP-binding protein; Provisional; Region: PRK14248
1034836007083	ATP-binding cassette domain of the phosphate transport system; Region: ABC_PstB_phosphate_transporter; cd03260
1034836007084	Walker A/P-loop; other site
1034836007085	ATP binding site [chemical binding]; other site
1034836007086	Q-loop/lid; other site
1034836007087	ABC transporter signature motif; other site
1034836007088	Walker B; other site
1034836007089	D-loop; other site
1034836007090	H-loop/switch region; other site
1034836007091	ABC-type phosphate transport system, permease component [Inorganic ion transport and metabolism]; Region: PstA; COG0581
1034836007092	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1034836007093	dimer interface [polypeptide binding]; other site
1034836007094	conserved gate region; other site
1034836007095	ABC-ATPase subunit interface; other site
1034836007096	phosphate ABC transporter, permease protein PstC; Region: phosphate_pstC; TIGR02138
1034836007097	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1034836007098	dimer interface [polypeptide binding]; other site
1034836007099	conserved gate region; other site
1034836007100	putative PBP binding loops; other site
1034836007101	ABC-ATPase subunit interface; other site
1034836007102	PBP superfamily domain; Region: PBP_like_2; cl17296
1034836007103	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
1034836007104	Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane]; Region: FtsI; COG0768
1034836007105	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
1034836007106	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
1034836007107	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1034836007108	putative substrate translocation pore; other site
1034836007109	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1034836007110	Superoxide dismutase [Inorganic ion transport and metabolism]; Region: SodA; COG0605
1034836007111	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
1034836007112	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
1034836007113	Protein of unknown function (DUF2827); Region: DUF2827; pfam10933
1034836007114	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2839
1034836007115	Protein of unknown function (DUF1189); Region: DUF1189; pfam06691
1034836007116	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cl00107
1034836007117	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Reviewed; Region: ispG; PRK00366
1034836007118	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
1034836007119	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
1034836007120	Uncharacterized conserved protein [Function unknown]; Region: COG5663
1034836007121	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
1034836007122	metal binding site 2 [ion binding]; metal-binding site
1034836007123	putative DNA binding helix; other site
1034836007124	metal binding site 1 [ion binding]; metal-binding site
1034836007125	dimer interface [polypeptide binding]; other site
1034836007126	structural Zn2+ binding site [ion binding]; other site
1034836007127	Uncharacterized conserved protein [Function unknown]; Region: COG1284
1034836007128	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
1034836007129	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
1034836007130	Uncharacterized protein conserved in bacteria (DUF2179); Region: DUF2179; pfam10035
1034836007131	Protein of unknown function (DUF2624); Region: DUF2624; pfam11116
1034836007132	endonuclease IV; Provisional; Region: PRK01060
1034836007133	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
1034836007134	AP (apurinic/apyrimidinic) site pocket; other site
1034836007135	DNA interaction; other site
1034836007136	Metal-binding active site; metal-binding site
1034836007137	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
1034836007138	DEAD-like helicases superfamily; Region: DEXDc; smart00487
1034836007139	ATP binding site [chemical binding]; other site
1034836007140	Mg++ binding site [ion binding]; other site
1034836007141	motif III; other site
1034836007142	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1034836007143	nucleotide binding region [chemical binding]; other site
1034836007144	ATP-binding site [chemical binding]; other site
1034836007145	YqfQ-like protein; Region: YqfQ; pfam14181
1034836007146	4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Reviewed; Region: ispH; PRK01045
1034836007147	LytB protein; Region: LYTB; pfam02401
1034836007148	Uncharacterized conserved protein [Function unknown]; Region: COG0327
1034836007149	NIF3 (NGG1p interacting factor 3); Region: NIF3; pfam01784
1034836007150	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3323
1034836007151	NIF3 (NGG1p interacting factor 3); Region: NIF3; pfam01784
1034836007152	Uncharacterized conserved protein [Function unknown]; Region: COG0327
1034836007153	Predicted SAM-dependent methyltransferase [General function prediction only]; Region: COG2384
1034836007154	Family of unknown function (DUF633); Region: DUF633; pfam04816
1034836007155	Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010
1034836007156	Cytochrome C oxidase, cbb3-type, subunit III; Region: Cytochrome_CBB3; pfam13442
1034836007157	RNA polymerase sigma factor RpoD; Validated; Region: PRK09210
1034836007158	Sigma-70 factor, region 1.1; Region: Sigma70_r1_1; pfam03979
1034836007159	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
1034836007160	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1034836007161	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
1034836007162	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1034836007163	DNA binding residues [nucleotide binding]
1034836007164	DNA primase; Validated; Region: dnaG; PRK05667
1034836007165	CHC2 zinc finger; Region: zf-CHC2; pfam01807
1034836007166	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
1034836007167	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
1034836007168	active site
1034836007169	metal binding site [ion binding]; metal-binding site
1034836007170	interdomain interaction site; other site
1034836007171	DnaB-helicase binding domain of primase; Region: DnaB_bind; pfam10410
1034836007172	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1671
1034836007173	PEP synthetase regulatory protein; Provisional; Region: PRK05339
1034836007174	HTH domain; Region: HTH_11; pfam08279
1034836007175	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair_4; cd04617
1034836007176	FOG: CBS domain [General function prediction only]; Region: COG0517
1034836007177	glycyl-tRNA synthetase subunit beta; Validated; Region: glyS; PRK01233
1034836007178	DALR anticodon binding domain; Region: DALR_1; pfam05746
1034836007179	Class II Glycyl-tRNA synthetase (GlyRS) alpha subunit core catalytic domain. GlyRS functions as a homodimer in eukaryotes, archaea and some bacteria and as a heterotetramer in the remainder of prokaryotes and in arabidopsis. It is responsible for the...; Region: GlyRS_alpha_core; cd00733
1034836007180	dimer interface [polypeptide binding]; other site
1034836007181	motif 1; other site
1034836007182	active site
1034836007183	motif 2; other site
1034836007184	motif 3; other site
1034836007185	Recombination protein O N terminal; Region: RecO_N; pfam11967
1034836007186	DNA repair protein RecO; Region: reco; TIGR00613
1034836007187	Recombination protein O C terminal; Region: RecO_C; pfam02565
1034836007188	YqzL-like protein; Region: YqzL; pfam14006
1034836007189	GTPase Era; Reviewed; Region: era; PRK00089
1034836007190	E. coli Ras-like protein (Era) is a multifunctional GTPase; Region: Era; cd04163
1034836007191	G1 box; other site
1034836007192	GTP/Mg2+ binding site [chemical binding]; other site
1034836007193	Switch I region; other site
1034836007194	G2 box; other site
1034836007195	Switch II region; other site
1034836007196	G3 box; other site
1034836007197	G4 box; other site
1034836007198	G5 box; other site
1034836007199	KH domain; Region: KH_2; pfam07650
1034836007200	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
1034836007201	active site
1034836007202	catalytic motif [active]
1034836007203	Zn binding site [ion binding]; other site
1034836007204	Diacylglycerol kinase [Cell envelope biogenesis, outer membrane]; Region: DgkA; COG0818
1034836007205	metal-binding heat shock protein; Provisional; Region: PRK00016
1034836007206	Predicted membrane-associated HD superfamily hydrolase [General function prediction only]; Region: COG1480
1034836007207	7TM receptor with intracellular HD hydrolase; Region: 7TM-7TMR_HD; pfam07698
1034836007208	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1034836007209	Zn2+ binding site [ion binding]; other site
1034836007210	Mg2+ binding site [ion binding]; other site
1034836007211	Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702
1034836007212	PhoH-like protein; Region: PhoH; pfam02562
1034836007213	Putative stage IV sporulation protein YqfD; Region: YqfD; pfam06898
1034836007214	sporulation protein YqfD; Region: spore_yqfD; TIGR02876
1034836007215	sporulation protein YqfC; Region: spore_yqfC; TIGR02856
1034836007216	hypothetical protein; Provisional; Region: PRK13665
1034836007217	Membrane-bound serine protease (ClpP class) [Posttranslational modification, protein turnover, chaperones]; Region: NfeD; COG1030
1034836007218	Nodulation formation efficiency D (NfeD) is a membrane-bound ClpP-class protease; Region: Clp_protease_NfeD_like; cd07021
1034836007219	dimer interface [polypeptide binding]; other site
1034836007220	active site residues [active]
1034836007221	NfeD-like C-terminal, partner-binding; Region: NfeD; cl00686
1034836007222	Yqey-like protein; Region: YqeY; pfam09424
1034836007223	30S ribosomal protein S21; Reviewed; Region: rpsU; PRK00270
1034836007224	Na/Pi-cotransporter; Region: NaPi_cotrn_rel; TIGR00704
1034836007225	Na+/Pi-cotransporter; Region: Na_Pi_cotrans; pfam02690
1034836007226	Na+/Pi-cotransporter; Region: Na_Pi_cotrans; pfam02690
1034836007227	2-methylthioadenine synthetase [Translation, ribosomal structure and biogenesis]; Region: MiaB; COG0621
1034836007228	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
1034836007229	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1034836007230	FeS/SAM binding site; other site
1034836007231	TRAM domain; Region: TRAM; cl01282
1034836007232	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1385
1034836007233	RNA methyltransferase, RsmE family; Region: TIGR00046
1034836007234	ribosomal protein L11 methyltransferase; Region: prmA; TIGR00406
1034836007235	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1034836007236	S-adenosylmethionine binding site [chemical binding]; other site
1034836007237	chaperone protein DnaJ; Provisional; Region: PRK14280
1034836007238	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
1034836007239	HSP70 interaction site [polypeptide binding]; other site
1034836007240	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cl03262
1034836007241	substrate binding site [polypeptide binding]; other site
1034836007242	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
1034836007243	Zn binding sites [ion binding]; other site
1034836007244	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
1034836007245	dimer interface [polypeptide binding]; other site
1034836007246	molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290
1034836007247	Nucleotide-binding domain of human HSPA9 and similar proteins; Region: HSPA9-Ssq1-like_NBD; cd10234
1034836007248	nucleotide binding site [chemical binding]; other site
1034836007249	NEF interaction site [polypeptide binding]; other site
1034836007250	SBD interface [polypeptide binding]; other site
1034836007251	GrpE; Region: GrpE; pfam01025
1034836007252	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446
1034836007253	dimer interface [polypeptide binding]; other site
1034836007254	hsp70 (ATPase domain) interactions [polypeptide binding]; other site
1034836007255	heat-inducible transcription repressor; Provisional; Region: hrcA; PRK00082
1034836007256	Winged helix-turn-helix transcription repressor, HrcA DNA-binding; Region: HrcA_DNA-bdg; pfam03444
1034836007257	coproporphyrinogen III oxidase; Provisional; Region: PRK08599
1034836007258	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1034836007259	FeS/SAM binding site; other site
1034836007260	HemN C-terminal domain; Region: HemN_C; pfam06969
1034836007261	GTP-binding protein LepA; Provisional; Region: PRK05433
1034836007262	LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890
1034836007263	G1 box; other site
1034836007264	putative GEF interaction site [polypeptide binding]; other site
1034836007265	GTP/Mg2+ binding site [chemical binding]; other site
1034836007266	Switch I region; other site
1034836007267	G2 box; other site
1034836007268	G3 box; other site
1034836007269	Switch II region; other site
1034836007270	G4 box; other site
1034836007271	G5 box; other site
1034836007272	lepA_II: This subfamily represents the domain II of LepA, a GTP-binding protein localized in the cytoplasmic membrane. The N-terminal domain of LepA shares regions of homology to translation factors. In terms of interaction with the ribosome, EF-G, EF-Tu...; Region: lepA_II; cd03699
1034836007273	lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane.   LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709
1034836007274	GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421
1034836007275	Protein of unknown function (DUF3679); Region: DUF3679; pfam12438
1034836007276	Stage II sporulation protein P (SpoIIP); Region: SpoIIP; pfam07454
1034836007277	stage II sporulation protein P; Region: spore_II_P; TIGR02867
1034836007278	germination protease; Provisional; Region: PRK02858
1034836007279	30S ribosomal protein S20; Reviewed; Region: rpsT; PRK00239
1034836007280	DNA polymerase III subunit delta; Reviewed; Region: holA; PRK05574
1034836007281	DNA polymerase III, delta subunit; Region: DNA_pol3_delta; pfam06144
1034836007282	YqzM-like protein; Region: YqzM; pfam14141
1034836007283	Domain of unknown function (DUF4131); Region: DUF4131; pfam13567
1034836007284	DNA internalization-related competence protein ComEC/Rec2; Region: ComEC_Rec2; TIGR00361
1034836007285	Competence protein; Region: Competence; pfam03772
1034836007286	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
1034836007287	Deoxycytidylate deaminase domain. Deoxycytidylate deaminase catalyzes the deamination of dCMP to dUMP, providing the nucleotide substrate for thymidylate synthase. The enzyme binds Zn++, which is required for catalytic activity. The activity of the...; Region: deoxycytidylate_deaminase; cd01286
1034836007288	catalytic motif [active]
1034836007289	Zn binding site [ion binding]; other site
1034836007290	SLBB domain; Region: SLBB; pfam10531
1034836007291	comEA protein; Region: comE; TIGR01259
1034836007292	Helix-hairpin-helix motif; Region: HHH; pfam00633
1034836007293	late competence protein ComER; Validated; Region: PRK07680
1034836007294	NADP oxidoreductase coenzyme F420-dependent; Region: F420_oxidored; cl17232
1034836007295	SAM-dependent methyltransferases [Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only]; Region: SmtA; COG0500
1034836007296	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1034836007297	S-adenosylmethionine binding site [chemical binding]; other site
1034836007298	Uncharacterized homolog of plant Iojap protein [Function unknown]; Region: COG0799
1034836007299	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1034836007300	Zn2+ binding site [ion binding]; other site
1034836007301	Mg2+ binding site [ion binding]; other site
1034836007302	nicotinic acid mononucleotide adenylyltransferase; Provisional; Region: nadD; PRK00071
1034836007303	Nicotinamide/nicotinate mononucleotide adenylyltransferase; Region: NMNAT; cd02165
1034836007304	active site
1034836007305	(T/H)XGH motif; other site
1034836007306	putative RNA-binding protein, YhbY family; Region: RNA_bind_YhbY; TIGR00253
1034836007307	shikimate 5-dehydrogenase; Reviewed; Region: aroE; PRK00258
1034836007308	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
1034836007309	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
1034836007310	shikimate binding site; other site
1034836007311	NAD(P) binding site [chemical binding]; other site
1034836007312	GTPase YqeH; Provisional; Region: PRK13796
1034836007313	Circularly permuted YqeH GTPase; Region: YqeH; cd01855
1034836007314	GTP/Mg2+ binding site [chemical binding]; other site
1034836007315	G4 box; other site
1034836007316	G5 box; other site
1034836007317	G1 box; other site
1034836007318	Switch I region; other site
1034836007319	G2 box; other site
1034836007320	G3 box; other site
1034836007321	Switch II region; other site
1034836007322	Predicted hydrolase of the HAD superfamily [General function prediction only]; Region: COG2179
1034836007323	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1034836007324	active site
1034836007325	motif I; other site
1034836007326	motif II; other site
1034836007327	Sporulation inhibitor A; Region: Sda; pfam08970
1034836007328	GDSL-like Lipase/Acylhydrolase; Region: Lipase_GDSL; pfam00657
1034836007329	active site
1034836007330	catalytic triad [active]
1034836007331	oxyanion hole [active]
1034836007332	Predicted xylanase/chitin deacetylase [Carbohydrate transport and metabolism]; Region: CDA1; COG0726
1034836007333	Catalytic NodB homology domain of rhizobial NodB-like proteins; Region: CE4_NodB_like_6s_7s; cd10917
1034836007334	NodB motif; other site
1034836007335	active site
1034836007336	catalytic site [active]
1034836007337	metal binding site [ion binding]; metal-binding site
1034836007338	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
1034836007339	amidase catalytic site [active]
1034836007340	Zn binding residues [ion binding]; other site
1034836007341	substrate binding site [chemical binding]; other site
1034836007342	Putative peptidoglycan-binding domain-containing protein [Cell envelope biogenesis, outer membrane]; Region: COG3409
1034836007343	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
1034836007344	Uncharacterized conserved protein [Function unknown]; Region: COG0398
1034836007345	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
1034836007346	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1034836007347	Coenzyme A binding pocket [chemical binding]; other site
1034836007348	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1034836007349	putative substrate translocation pore; other site
1034836007350	sporulation sigma factor SigK; Reviewed; Region: PRK05803
1034836007351	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1034836007352	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1034836007353	DNA binding residues [nucleotide binding]
1034836007354	Domain of unknown function (DUF303); Region: DUF303; pfam03629
1034836007355	Transcriptional regulator PadR-like family; Region: PadR; cl17335
1034836007356	Predicted transcriptional regulators [Transcription]; Region: COG1695
1034836007357	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1034836007358	DNA binding residues [nucleotide binding]
1034836007359	hypothetical protein; Validated; Region: PRK06217
1034836007360	Adenylate kinase and related kinases [Nucleotide transport and metabolism]; Region: Adk; COG0563
1034836007361	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1034836007362	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1034836007363	putative substrate translocation pore; other site
1034836007364	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1034836007365	DinB family; Region: DinB; pfam05163
1034836007366	DinB superfamily; Region: DinB_2; pfam12867
1034836007367	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cl17915
1034836007368	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
1034836007369	active site
1034836007370	motif I; other site
1034836007371	motif II; other site
1034836007372	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1034836007373	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
1034836007374	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1034836007375	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
1034836007376	active site
1034836007377	motif I; other site
1034836007378	motif II; other site
1034836007379	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
1034836007380	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
1034836007381	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
1034836007382	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
1034836007383	putative active site [active]
1034836007384	Phosphomannose isomerase [Carbohydrate transport and metabolism]; Region: ManA; COG1482
1034836007385	mannose-6-phosphate isomerase, class I; Region: manA; TIGR00218
1034836007386	putative PTS system  transporter subunits IIBC; Provisional; Region: PRK11404
1034836007387	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
1034836007388	active site
1034836007389	P-loop; other site
1034836007390	phosphorylation site [posttranslational modification]
1034836007391	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299
1034836007392	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1034836007393	active site
1034836007394	phosphorylation site [posttranslational modification]
1034836007395	Transcriptional antiterminator [Transcription]; Region: BglG; COG3711
1034836007396	HTH domain; Region: HTH_11; cl17392
1034836007397	Mga helix-turn-helix domain; Region: Mga; pfam05043
1034836007398	PRD domain; Region: PRD; pfam00874
1034836007399	PRD domain; Region: PRD; pfam00874
1034836007400	PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568
1034836007401	active site
1034836007402	P-loop; other site
1034836007403	phosphorylation site [posttranslational modification]
1034836007404	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1034836007405	active site
1034836007406	phosphorylation site [posttranslational modification]
1034836007407	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
1034836007408	Metallo-beta-lactamase superfamily; Region: Lactamase_B; cl00446
1034836007409	This CD includes cysteinyl-tRNA(Pro) deacylases from Haemophilus influenzae and Escherichia coli and other related bacterial proteins. These trans-acting, single-domain proteins are homologs of ProX and also the cis-acting prolyl-tRNA synthetase (ProRS)...; Region: YbaK_deacylase; cd00002
1034836007410	putative deacylase active site [active]
1034836007411	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1034836007412	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1034836007413	The substrate binding domain of LysR-type transcriptional regulator GltC, which activates gltA expression of glutamate synthase operon, contains type 2 periplasmic binding fold; Region: PBP2_GltC_like; cd08434
1034836007414	putative dimerization interface [polypeptide binding]; other site
1034836007415	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
1034836007416	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1034836007417	putative substrate translocation pore; other site
1034836007418	Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]; Region: CypX; COG2124
1034836007419	Cytochrome P450; Region: p450; pfam00067
1034836007420	Sulfite reductase, alpha subunit (flavoprotein) [Inorganic ion transport and metabolism]; Region: CysJ; COG0369
1034836007421	Flavodoxin; Region: Flavodoxin_1; pfam00258
1034836007422	These bifunctional proteins fuse N-terminal cytochrome p450 with a cytochrome p450 reductase (CYPOR). NADPH cytochrome p450 reductase serves as an electron donor in several oxygenase systems and is a component of nitric oxide synthases and methionine...; Region: bifunctional_CYPOR; cd06206
1034836007423	FAD binding pocket [chemical binding]; other site
1034836007424	FAD binding motif [chemical binding]; other site
1034836007425	catalytic residues [active]
1034836007426	NAD binding pocket [chemical binding]; other site
1034836007427	phosphate binding motif [ion binding]; other site
1034836007428	beta-alpha-beta structure motif; other site
1034836007429	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1034836007430	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1034836007431	Methyltransferase domain; Region: Methyltransf_11; pfam08241
1034836007432	Probable sporulation protein (Bac_small_yrzI); Region: Bac_small_YrzI; cl09734
1034836007433	Formate/nitrite transporter; Region: Form_Nir_trans; pfam01226
1034836007434	Uncharacterized conserved protein [Function unknown]; Region: COG5609
1034836007435	Uncharacterized anaerobic dehydrogenase [General function prediction only]; Region: COG3383
1034836007436	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1034836007437	catalytic loop [active]
1034836007438	iron binding site [ion binding]; other site
1034836007439	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Region: NADH-G_4Fe-4S_3; pfam10588
1034836007440	4Fe-4S binding domain; Region: Fer4; pfam00037
1034836007441	Formate dehydrogenase H (Formate-Dh-H) catalyzes the reversible oxidation of formate to CO2 with the release of a proton and two electrons. It is a component of the anaerobic formate hydrogen lyase complex. The E. coli formate dehydrogenase H (Fdh-H) is...; Region: MopB_Formate-Dh-H; cd02753
1034836007442	[4Fe-4S] binding site [ion binding]; other site
1034836007443	molybdopterin cofactor binding site; other site
1034836007444	Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_CT_Formate-Dh-Na-like; cd02792
1034836007445	molybdopterin cofactor binding site; other site
1034836007446	Uncharacterized conserved protein [Function unknown]; Region: COG2427
1034836007447	YrhC-like protein; Region: YrhC; pfam14143
1034836007448	cystathionine beta-lyase; Provisional; Region: PRK07671
1034836007449	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
1034836007450	homodimer interface [polypeptide binding]; other site
1034836007451	substrate-cofactor binding pocket; other site
1034836007452	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1034836007453	catalytic residue [active]
1034836007454	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
1034836007455	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
1034836007456	dimer interface [polypeptide binding]; other site
1034836007457	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1034836007458	catalytic residue [active]
1034836007459	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Validated; Region: PRK05584
1034836007460	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Region: MTA/SAH-Nsdase; TIGR01704
1034836007461	Methyltransferase domain; Region: Methyltransf_31; pfam13847
1034836007462	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1034836007463	S-adenosylmethionine binding site [chemical binding]; other site
1034836007464	Protein of unknown function (DUF2536); Region: DUF2536; pfam10750
1034836007465	Protein of unknown function (DUF1510); Region: DUF1510; pfam07423
1034836007466	Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane]; Region: FtsI; COG0768
1034836007467	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
1034836007468	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
1034836007469	transcription elongation factor GreA; Reviewed; Region: greA; PRK00226
1034836007470	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
1034836007471	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
1034836007472	Uridine kinase [Nucleotide transport and metabolism]; Region: Udk; COG0572
1034836007473	Uridine monophosphate kinase (UMPK, EC 2.7.1.48), also known as uridine kinase or uridine-cytidine kinase (UCK), catalyzes the reversible phosphoryl transfer from ATP to uridine or cytidine to yield UMP or CMP. In the primidine nucleotide-salvage pathway; Region: UMPK; cd02023
1034836007474	Sugar specificity; other site
1034836007475	Pyrimidine base specificity; other site
1034836007476	ATP-binding site [chemical binding]; other site
1034836007477	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
1034836007478	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
1034836007479	Peptidase family U32; Region: Peptidase_U32; pfam01136
1034836007480	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
1034836007481	Peptidase family U32; Region: Peptidase_U32; pfam01136
1034836007482	Predicted O-methyltransferase [General function prediction only]; Region: COG4122
1034836007483	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1034836007484	S-adenosylmethionine binding site [chemical binding]; other site
1034836007485	conserved hypothetical protein, YceG family; Region: TIGR00247
1034836007486	proteins similar to Escherichia coli yceG; Region: yceG_like; cd08010
1034836007487	dimerization interface [polypeptide binding]; other site
1034836007488	hypothetical protein; Provisional; Region: PRK13678
1034836007489	RNAse H-fold protein YqgF; Region: RNAse_H_YqgF; TIGR00250
1034836007490	hypothetical protein; Provisional; Region: PRK05473
1034836007491	alanyl-tRNA synthetase; Reviewed; Region: alaS; PRK00252
1034836007492	Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: AlaRS_core; cd00673
1034836007493	motif 1; other site
1034836007494	active site
1034836007495	motif 2; other site
1034836007496	motif 3; other site
1034836007497	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
1034836007498	DHHA1 domain; Region: DHHA1; pfam02272
1034836007499	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
1034836007500	Domain of unknown function DUF20; Region: UPF0118; pfam01594
1034836007501	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
1034836007502	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1034836007503	Walker A/P-loop; other site
1034836007504	ATP binding site [chemical binding]; other site
1034836007505	Q-loop/lid; other site
1034836007506	ABC transporter signature motif; other site
1034836007507	Walker B; other site
1034836007508	D-loop; other site
1034836007509	H-loop/switch region; other site
1034836007510	Bacterial periplasmic substrate-binding proteins; Region: PBPb; smart00062
1034836007511	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1034836007512	substrate binding pocket [chemical binding]; other site
1034836007513	membrane-bound complex binding site; other site
1034836007514	hinge residues; other site
1034836007515	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1034836007516	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1034836007517	dimer interface [polypeptide binding]; other site
1034836007518	conserved gate region; other site
1034836007519	putative PBP binding loops; other site
1034836007520	ABC-ATPase subunit interface; other site
1034836007521	amine acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family; Region: HEQRo_perm_3TM; TIGR01726
1034836007522	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1034836007523	dimer interface [polypeptide binding]; other site
1034836007524	ABC-ATPase subunit interface; other site
1034836007525	putative PBP binding loops; other site
1034836007526	PRC-barrel domain containing protein [General function prediction only]; Region: COG3881
1034836007527	helicase, putative, RecD/TraA family; Region: recD_rel; TIGR01448
1034836007528	AAA domain; Region: AAA_30; pfam13604
1034836007529	Family description; Region: UvrD_C_2; pfam13538
1034836007530	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1034836007531	binding surface
1034836007532	TPR repeat; Region: TPR_11; pfam13414
1034836007533	TPR motif; other site
1034836007534	TPR repeat; Region: TPR_11; pfam13414
1034836007535	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1034836007536	binding surface
1034836007537	TPR motif; other site
1034836007538	TPR repeat; Region: TPR_11; pfam13414
1034836007539	tRNA methyl transferase; Region: tRNA_Me_trans; pfam03054
1034836007540	tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998
1034836007541	Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism]; Region: NifS; COG1104
1034836007542	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
1034836007543	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1034836007544	catalytic residue [active]
1034836007545	Predicted transcriptional regulator [Transcription]; Region: COG1959
1034836007546	Transcriptional regulator; Region: Rrf2; pfam02082
1034836007547	recombination factor protein RarA; Reviewed; Region: PRK13342
1034836007548	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1034836007549	Walker A motif; other site
1034836007550	ATP binding site [chemical binding]; other site
1034836007551	Walker B motif; other site
1034836007552	arginine finger; other site
1034836007553	MgsA AAA+ ATPase C terminal; Region: MgsA_C; pfam12002
1034836007554	Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 [Coenzyme metabolism]; Region: COG1179
1034836007555	Family of activating enzymes (E1) of ubiquitin-like proteins related to the E.coli hypothetical protein ygdL. The common reaction mechanism catalyzed by E1-like enzymes begins with a nucleophilic attack of the C-terminal carboxylate of the ubiquitin-like...; Region: YgdL_like; cd00755
1034836007556	putative ATP binding site [chemical binding]; other site
1034836007557	putative substrate interface [chemical binding]; other site
1034836007558	aspartyl-tRNA synthetase; Validated; Region: aspS; PRK00476
1034836007559	EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; Region: EcAspRS_like_N; cd04317
1034836007560	dimer interface [polypeptide binding]; other site
1034836007561	anticodon binding site; other site
1034836007562	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
1034836007563	homodimer interface [polypeptide binding]; other site
1034836007564	motif 1; other site
1034836007565	active site
1034836007566	motif 2; other site
1034836007567	GAD domain; Region: GAD; pfam02938
1034836007568	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
1034836007569	active site
1034836007570	motif 3; other site
1034836007571	histidyl-tRNA synthetase; Reviewed; Region: hisS; PRK00037
1034836007572	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
1034836007573	dimer interface [polypeptide binding]; other site
1034836007574	motif 1; other site
1034836007575	active site
1034836007576	motif 2; other site
1034836007577	motif 3; other site
1034836007578	HisRS Histidyl-anticodon binding domain. HisRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: HisRS_anticodon; cd00859
1034836007579	anticodon binding site; other site
1034836007580	SH3 domain protein [Signal transduction mechanisms]; Region: COG3103
1034836007581	Bacterial SH3 domain; Region: SH3_3; pfam08239
1034836007582	Bacterial SH3 domain; Region: SH3_3; pfam08239
1034836007583	Bacterial SH3 domain; Region: SH3_3; pfam08239
1034836007584	Bacterial SH3 domain homologues; Region: SH3b; smart00287
1034836007585	N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: AmiC; COG0860
1034836007586	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
1034836007587	active site
1034836007588	metal binding site [ion binding]; metal-binding site
1034836007589	D-Tyrosyl-tRNAtyr deacylases; a class of tRNA-dependent hydrolases which are capable of hydrolyzing the ester bond of D-Tyrosyl-tRNA reducing the level of cellular D-Tyrosine while recycling the peptidyl-tRNA; found in bacteria and in eukaryotes but not...; Region: Dtyr_deacylase; cd00563
1034836007590	putative active site [active]
1034836007591	dimerization interface [polypeptide binding]; other site
1034836007592	putative tRNAtyr binding site [nucleotide binding]; other site
1034836007593	Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription]; Region: SpoT; COG0317
1034836007594	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1034836007595	Zn2+ binding site [ion binding]; other site
1034836007596	Mg2+ binding site [ion binding]; other site
1034836007597	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
1034836007598	synthetase active site [active]
1034836007599	NTP binding site [chemical binding]; other site
1034836007600	metal binding site [ion binding]; metal-binding site
1034836007601	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
1034836007602	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
1034836007603	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1034836007604	active site
1034836007605	single-stranded-DNA-specific exonuclease RecJ; Region: recJ; TIGR00644
1034836007606	DHH family; Region: DHH; pfam01368
1034836007607	DHHA1 domain; Region: DHHA1; pfam02272
1034836007608	Single-strand DNA-specific exonuclease, C terminal domain; Region: ssDNA-exonuc_C; pfam10141
1034836007609	Uncharacterized integral membrane protein [Function unknown]; Region: COG5416
1034836007610	Putative regulatory, ligand-binding protein related to C-terminal domains of K+ channels [Inorganic ion transport and metabolism]; Region: COG0490
1034836007611	TrkA-C domain; Region: TrkA_C; pfam02080
1034836007612	bifunctional preprotein translocase subunit SecD/SecF; Reviewed; Region: PRK13024
1034836007613	protein-export membrane protein, SecD/SecF family; Region: 2A0604s01; TIGR00916
1034836007614	Protein export membrane protein; Region: SecD_SecF; pfam02355
1034836007615	Post-transcriptional regulator; Region: Post_transc_reg; pfam13797
1034836007616	stage V sporulation protein B; Region: spore_V_B; TIGR02900
1034836007617	Stage V sporulation protein B, also known as Stage III sporulation protein F, and related proteins; Region: MATE_SpoVB_like; cd13124
1034836007618	Predicted membrane protein [Function unknown]; Region: COG2323
1034836007619	Protein of unknown function (DUF3792); Region: DUF3792; pfam12670
1034836007620	preprotein translocase subunit YajC; Validated; Region: yajC; PRK05585
1034836007621	queuine tRNA-ribosyltransferase; Provisional; Region: tgt; PRK00112
1034836007622	Queuine/archaeosine tRNA-ribosyltransferase [Translation, ribosomal structure and biogenesis]; Region: Tgt; COG0343
1034836007623	potential frameshift: common BLAST hit: gi|154686913|ref|YP_001422074.1| S-adenosylmethionine:tRNA ribosyltransferase-isomerase
1034836007624	Protein of unknown function (DUF2905); Region: DUF2905; pfam11146
1034836007625	Holliday junction DNA helicase RuvB; Reviewed; Region: ruvB; PRK00080
1034836007626	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1034836007627	Walker A motif; other site
1034836007628	ATP binding site [chemical binding]; other site
1034836007629	Walker B motif; other site
1034836007630	arginine finger; other site
1034836007631	Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491
1034836007632	Holliday junction DNA helicase RuvA; Reviewed; Region: ruvA; PRK00116
1034836007633	RuvA N terminal domain; Region: RuvA_N; pfam01330
1034836007634	RuvA, C-terminal domain; Region: RuvA_C; pfam07499
1034836007635	Bypass of Forespore C, N terminal; Region: BOFC_N; pfam08977
1034836007636	BofC C-terminal domain; Region: BofC_C; pfam08955
1034836007637	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ); Region: Spore_YhcN_YlaJ; pfam09580
1034836007638	FOG: LysM repeat [Cell envelope biogenesis, outer membrane]; Region: LytE; COG1388
1034836007639	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1034836007640	quinolinate synthetase; Provisional; Region: PRK09375
1034836007641	nicotinate-nucleotide pyrophosphorylase; Provisional; Region: PRK08072
1034836007642	Quinolinate phosphoribosyl transferase (QAPRTase or QPRTase), also called nicotinate-nucleotide pyrophosphorylase, is involved in the de novo synthesis of NAD in both prokaryotes and eukaryotes. It catalyses the reaction of quinolinic acid (QA) with...; Region: QPRTase; cd01572
1034836007643	dimerization interface [polypeptide binding]; other site
1034836007644	active site
1034836007645	L-aspartate oxidase; Provisional; Region: PRK08071
1034836007646	L-aspartate oxidase; Provisional; Region: PRK06175
1034836007647	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
1034836007648	cysteine desulfurase; Provisional; Region: PRK02948
1034836007649	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
1034836007650	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1034836007651	catalytic residue [active]
1034836007652	Predicted small molecule binding protein (contains 3H domain) [General function prediction only]; Region: COG1827
1034836007653	HTH domain; Region: HTH_11; pfam08279
1034836007654	3H domain; Region: 3H; pfam02829
1034836007655	prephenate dehydratase; Provisional; Region: PRK11898
1034836007656	Prephenate dehydratase; Region: PDT; pfam00800
1034836007657	C-terminal ACT domain of the bifunctional chorismate mutase-prephenate dehydratase (CM-PDT) enzyme and the prephenate dehydratase (PDT) enzyme; Region: ACT_CM-PDT; cd04905
1034836007658	putative L-Phe binding site [chemical binding]; other site
1034836007659	hypothetical protein; Provisional; Region: PRK04435
1034836007660	C-terminal ACT domain of a small (; 147 a.a.) putative phenylalanine biosynthetic pathway protein described in Bacillus subtilis (BS) PheB (PheB-BS) and related domains; Region: ACT_PheB-BS; cd04888
1034836007661	GTPase CgtA; Reviewed; Region: obgE; PRK12297
1034836007662	GTP1/OBG; Region: GTP1_OBG; pfam01018
1034836007663	Obg GTPase; Region: Obg; cd01898
1034836007664	G1 box; other site
1034836007665	GTP/Mg2+ binding site [chemical binding]; other site
1034836007666	Switch I region; other site
1034836007667	G2 box; other site
1034836007668	G3 box; other site
1034836007669	Switch II region; other site
1034836007670	G4 box; other site
1034836007671	G5 box; other site
1034836007672	Domain of unknown function (DUF1967); Region: DUF1967; pfam09269
1034836007673	Signal transduction histidine kinase regulating citrate/malate metabolism [Signal transduction mechanisms]; Region: CitA; COG3290
1034836007674	50S ribosomal protein L27; Validated; Region: rpmA; PRK05435
1034836007675	hypothetical protein; Provisional; Region: PRK14553
1034836007676	50S ribosomal protein L21/unknown domain fusion protein; Provisional; Region: PRK12278
1034836007677	50S ribosomal protein L21; Validated; Region: rplU; PRK05573
1034836007678	SpoIVFB Site-2 protease (S2P), a zinc metalloprotease (MEROPS family M50B), regulates intramembrane proteolysis (RIP), and is involved in the pro-sigmaK pathway of bacterial spore formation. SpoIVFB (sporulation protein, stage IV cell wall formation, F...; Region: S2P-M50_SpoIVFB; cd06161
1034836007679	Peptidase family M50; Region: Peptidase_M50; pfam02163
1034836007680	active site
1034836007681	putative substrate binding region [chemical binding]; other site
1034836007682	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
1034836007683	Peptidase family M23; Region: Peptidase_M23; pfam01551
1034836007684	septum site-determining protein MinD; Region: minD_bact; TIGR01968
1034836007685	Bacterial cell division requires the formation of a septum at mid-cell. The site is determined by the min operon products MinC, MinD and MinE. MinC is a nonspecific inhibitor of the septum protein FtsZ. MinE is the supressor of MinC. MinD plays a pivotal...; Region: MinD; cd02036
1034836007686	Switch I; other site
1034836007687	Switch II; other site
1034836007688	septum formation inhibitor; Reviewed; Region: minC; PRK00513
1034836007689	Septum formation inhibitor MinC, C-terminal domain; Region: MinC_C; pfam03775
1034836007690	Cell shape-determining protein [Cell envelope biogenesis, outer membrane]; Region: MreD; COG2891
1034836007691	rod shape-determining protein MreC; Region: mreC; TIGR00219
1034836007692	rod shape-determining protein MreC; Region: MreC; pfam04085
1034836007693	rod shape-determining protein MreB; Provisional; Region: PRK13927
1034836007694	MreB and similar proteins; Region: MreB_like; cd10225
1034836007695	nucleotide binding site [chemical binding]; other site
1034836007696	Mg binding site [ion binding]; other site
1034836007697	putative protofilament interaction site [polypeptide binding]; other site
1034836007698	RodZ interaction site [polypeptide binding]; other site
1034836007699	hypothetical protein; Reviewed; Region: PRK00024
1034836007700	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
1034836007701	MPN+ (JAMM) motif; other site
1034836007702	Zinc-binding site [ion binding]; other site
1034836007703	Maf-like protein; Region: Maf; pfam02545
1034836007704	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
1034836007705	active site
1034836007706	dimer interface [polypeptide binding]; other site
1034836007707	Sporulation related domain; Region: SPOR; pfam05036
1034836007708	Type II secretory pathway, prepilin signal peptidase PulO and related peptidases [Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: PulO; COG1989
1034836007709	Bacterial Peptidase A24 N-terminal domain; Region: DiS_P_DiS; pfam06750
1034836007710	Type IV leader peptidase family; Region: Peptidase_A24; pfam01478
1034836007711	Folylpolyglutamate synthase [Coenzyme metabolism]; Region: FolC; COG0285
1034836007712	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1034836007713	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1034836007714	valyl-tRNA synthetase; Reviewed; Region: valS; PRK05729
1034836007715	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1034836007716	active site
1034836007717	HIGH motif; other site
1034836007718	nucleotide binding site [chemical binding]; other site
1034836007719	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
1034836007720	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
1034836007721	active site
1034836007722	KMSKS motif; other site
1034836007723	Anticodon-binding domain of valyl tRNA synthetases; Region: Anticodon_Ia_Val; cd07962
1034836007724	tRNA binding surface [nucleotide binding]; other site
1034836007725	anticodon binding site; other site
1034836007726	Valyl tRNA synthetase tRNA binding arm; Region: Val_tRNA-synt_C; pfam10458
1034836007727	spore coat protein YsxE; Region: spore_ysxE; TIGR02904
1034836007728	spore coat protein, CotS family; Region: spore_CotS; TIGR02906
1034836007729	stage VI sporulation protein D; Region: spore_VI_D; TIGR02907
1034836007730	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1034836007731	glutamate-1-semialdehyde aminotransferase; Provisional; Region: PRK00062
1034836007732	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1034836007733	inhibitor-cofactor binding pocket; inhibition site
1034836007734	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1034836007735	catalytic residue [active]
1034836007736	Porphobilinogen synthase (PBGS), which is also called delta-aminolevulinic acid dehydratase (ALAD), catalyzes the condensation of two 5-aminolevulinic acid (ALA) molecules to form the pyrrole porphobilinogen (PBG), which is the second step in the...; Region: ALAD_PBGS; cd00384
1034836007737	dimer interface [polypeptide binding]; other site
1034836007738	active site
1034836007739	Schiff base residues; other site
1034836007740	Uroporphyrinogen-III synthase [Coenzyme metabolism]; Region: HemD; COG1587
1034836007741	Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in...; Region: HemD; cd06578
1034836007742	active site
1034836007743	porphobilinogen deaminase; Reviewed; Region: hemC; PRK00072
1034836007744	Hydroxymethylbilane synthase (HMBS), also known as porphobilinogen deaminase (PBGD), is an intermediate enzyme in the biosynthetic pathway of tetrapyrrolic ring systems, such as heme, chlorophylls, and vitamin B12. HMBS catalyzes the conversion of...; Region: HMBS; cd00494
1034836007745	domain interfaces; other site
1034836007746	active site
1034836007747	Cytochrome C assembly protein; Region: Cytochrom_C_asm; pfam01578
1034836007748	glutamyl-tRNA reductase; Reviewed; Region: hemA; PRK00045
1034836007749	NADP-binding domain of glutamyl-tRNA reductase; Region: NAD_bind_Glutamyl_tRNA_reduct; cd05213
1034836007750	tRNA; other site
1034836007751	putative tRNA binding site [nucleotide binding]; other site
1034836007752	putative NADP binding site [chemical binding]; other site
1034836007753	Glutamyl-tRNAGlu reductase, dimerisation domain; Region: GlutR_dimer; pfam00745
1034836007754	YihA (EngB) GTPase family; Region: YihA_EngB; cd01876
1034836007755	G1 box; other site
1034836007756	GTP/Mg2+ binding site [chemical binding]; other site
1034836007757	Switch I region; other site
1034836007758	G2 box; other site
1034836007759	G3 box; other site
1034836007760	Switch II region; other site
1034836007761	G4 box; other site
1034836007762	G5 box; other site
1034836007763	ATP-dependent Lon protease, bacterial type [Posttranslational modification, protein turnover, chaperones]; Region: Lon; COG0466
1034836007764	Found in ATP-dependent protease La (LON); Region: LON; smart00464
1034836007765	Found in ATP-dependent protease La (LON); Region: LON; smart00464
1034836007766	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1034836007767	Walker A motif; other site
1034836007768	ATP binding site [chemical binding]; other site
1034836007769	Walker B motif; other site
1034836007770	arginine finger; other site
1034836007771	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
1034836007772	ATP-dependent protease LonB; Region: spore_lonB; TIGR02902
1034836007773	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1034836007774	Walker A motif; other site
1034836007775	ATP binding site [chemical binding]; other site
1034836007776	Walker B motif; other site
1034836007777	arginine finger; other site
1034836007778	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
1034836007779	ATP-dependent protease ATP-binding subunit ClpX; Provisional; Region: clpX; PRK05342
1034836007780	ClpX C4-type zinc finger; Region: zf-C4_ClpX; pfam06689
1034836007781	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1034836007782	Walker A motif; other site
1034836007783	ATP binding site [chemical binding]; other site
1034836007784	Walker B motif; other site
1034836007785	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
1034836007786	trigger factor; Provisional; Region: tig; PRK01490
1034836007787	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1034836007788	Bacterial trigger factor protein (TF) C-terminus; Region: Trigger_C; pfam05698
1034836007789	TPR repeat; Region: TPR_11; pfam13414
1034836007790	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1034836007791	binding surface
1034836007792	TPR motif; other site
1034836007793	isopropylmalate isomerase small subunit; Provisional; Region: leuD; PRK01641
1034836007794	Aconatase-like swivel domain of 3-isopropylmalate dehydratase and related uncharacterized proteins. 3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate...; Region: IPMI_Swivel; cd01577
1034836007795	substrate binding site [chemical binding]; other site
1034836007796	3-isopropylmalate dehydratase large subunit; Reviewed; Region: PRK00402
1034836007797	3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; Region: IPMI; cd01583
1034836007798	substrate binding site [chemical binding]; other site
1034836007799	ligand binding site [chemical binding]; other site
1034836007800	3-isopropylmalate dehydrogenase; Provisional; Region: PRK00772
1034836007801	tartrate dehydrogenase; Region: TTC; TIGR02089
1034836007802	2-isopropylmalate synthase; Validated; Region: PRK00915
1034836007803	2-isopropylmalate synthase (IPMS), N-terminal catalytic TIM barrel domain; Region: DRE_TIM_IPMS; cd07940
1034836007804	active site
1034836007805	catalytic residues [active]
1034836007806	metal binding site [ion binding]; metal-binding site
1034836007807	LeuA allosteric (dimerisation) domain; Region: LeuA_dimer; pfam08502
1034836007808	ketol-acid reductoisomerase; Provisional; Region: PRK05479
1034836007809	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvN; pfam07991
1034836007810	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
1034836007811	acetolactate synthase 3 regulatory subunit; Reviewed; Region: ilvH; PRK11895
1034836007812	N-terminal ACT domain of the Escherichia coli IlvH-like regulatory subunit of acetohydroxyacid synthase (AHAS); Region: ACT_AHAS; cd04878
1034836007813	putative valine binding site [chemical binding]; other site
1034836007814	dimer interface [polypeptide binding]; other site
1034836007815	Small subunit of acetolactate synthase; Region: ALS_ss_C; pfam10369
1034836007816	acetolactate synthase catalytic subunit; Reviewed; Region: PRK07710
1034836007817	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
1034836007818	PYR/PP interface [polypeptide binding]; other site
1034836007819	dimer interface [polypeptide binding]; other site
1034836007820	TPP binding site [chemical binding]; other site
1034836007821	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1034836007822	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
1034836007823	TPP-binding site [chemical binding]; other site
1034836007824	dimer interface [polypeptide binding]; other site
1034836007825	Escherichia coli YfcE and related proteins, metallophosphatase domain; Region: MPP_YfcE; cd00841
1034836007826	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
1034836007827	active site
1034836007828	metal binding site [ion binding]; metal-binding site
1034836007829	homotetramer interface [polypeptide binding]; other site
1034836007830	NTPase/HAM1.  This family consists of the HAM1 protein and pyrophosphate-releasing xanthosine/ inosine triphosphatase. HAM1 protects the cell against mutagenesis by the base analog 6-N-hydroxylaminopurine (HAP) in E. Coli and S. cerevisiae. A...; Region: HAM1; cd00515
1034836007831	active site
1034836007832	dimerization interface [polypeptide binding]; other site
1034836007833	ribonuclease PH; Reviewed; Region: rph; PRK00173
1034836007834	Ribonuclease PH; Region: RNase_PH_bact; cd11362
1034836007835	hexamer interface [polypeptide binding]; other site
1034836007836	active site
1034836007837	Sporulation and spore germination; Region: Germane; pfam10646
1034836007838	Spore germination protein [General function prediction only]; Region: COG5401
1034836007839	Sporulation and spore germination; Region: Germane; pfam10646
1034836007840	glutamate racemase; Provisional; Region: PRK00865
1034836007841	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1034836007842	MarR family; Region: MarR; pfam01047
1034836007843	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1034836007844	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1034836007845	DNA binding residues [nucleotide binding]
1034836007846	dimerization interface [polypeptide binding]; other site
1034836007847	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
1034836007848	active site
1034836007849	succinate dehydrogenase iron-sulfur subunit; Reviewed; Region: sdhB; PRK08640
1034836007850	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
1034836007851	succinate dehydrogenase flavoprotein subunit; Reviewed; Region: sdhA; PRK08641
1034836007852	L-aspartate oxidase; Provisional; Region: PRK06175
1034836007853	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
1034836007854	Succinate:quinone oxidoreductase (SQR) Type B subfamily 1, transmembrane subunit; composed of proteins similar to Bacillus subtilis SQR. SQR catalyzes the oxidation of succinate to fumarate coupled to the reduction of quinone to quinol. Bacillus subtilis...; Region: SQR_TypeB_1_TM; cd03497
1034836007855	putative Iron-sulfur protein interface [polypeptide binding]; other site
1034836007856	succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family; Region: sdhC_b558_fam; TIGR02046
1034836007857	proximal heme binding site [chemical binding]; other site
1034836007858	distal heme binding site [chemical binding]; other site
1034836007859	putative dimer interface [polypeptide binding]; other site
1034836007860	Protein of unknown function (DUF2507); Region: DUF2507; pfam10702
1034836007861	aspartate kinase; Reviewed; Region: PRK06635
1034836007862	AAK_AKii-LysC-BS: Amino Acid Kinase Superfamily (AAK), AKii; this CD includes the N-terminal catalytic aspartokinase (AK) domain of the lysine-sensitive aspartokinase isoenzyme AKII of Bacillus subtilis 168, and the lysine plus threonine-sensitive...; Region: AAK_AKii-LysC-BS; cd04261
1034836007863	putative nucleotide binding site [chemical binding]; other site
1034836007864	putative catalytic residues [active]
1034836007865	putative Mg ion binding site [ion binding]; other site
1034836007866	putative aspartate binding site [chemical binding]; other site
1034836007867	ACT domains of the lysine-sensitive aspartokinase isoenzyme AKII of Bacillus subtilis (BS) strain 168 and related proteins; Region: ACT_AKii-LysC-BS-like_1; cd04913
1034836007868	putative allosteric regulatory site; other site
1034836007869	ACT domains of the lysine-sensitive aspartokinase isoenzyme AKII of Bacillus subtilis (BS) strain 168 and related domains; Region: ACT_AK-LysC-DapG-like_2; cd04923
1034836007870	excinuclease ABC subunit C; Validated; Region: uvrC; PRK00558
1034836007871	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
1034836007872	GIY-YIG motif/motif A; other site
1034836007873	active site
1034836007874	catalytic site [active]
1034836007875	putative DNA binding site [nucleotide binding]; other site
1034836007876	metal binding site [ion binding]; metal-binding site
1034836007877	UvrB/uvrC motif; Region: UVR; pfam02151
1034836007878	UvrC Helix-hairpin-helix N-terminal; Region: UvrC_HhH_N; pfam08459
1034836007879	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
1034836007880	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
1034836007881	catalytic residues [active]
1034836007882	Alpha-L-arabinofuranosidase [Carbohydrate transport and metabolism]; Region: AbfA; COG3534
1034836007883	Alpha-L-arabinofuranosidase C-terminus; Region: Alpha-L-AF_C; pfam06964
1034836007884	Electron transfer flavoprotein, alpha subunit [Energy production and conversion]; Region: FixB; COG2025
1034836007885	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_alpha; cd01715
1034836007886	Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766
1034836007887	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_beta; cd01714
1034836007888	Ligand binding site [chemical binding]; other site
1034836007889	Electron transfer flavoprotein domain; Region: ETF; pfam01012
1034836007890	enoyl-CoA hydratase; Provisional; Region: PRK07658
1034836007891	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
1034836007892	substrate binding site [chemical binding]; other site
1034836007893	oxyanion hole (OAH) forming residues; other site
1034836007894	trimer interface [polypeptide binding]; other site
1034836007895	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1034836007896	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1034836007897	YsiA-like protein, C-terminal region; Region: TetR_C_4; pfam08359
1034836007898	long-chain-fatty-acid--CoA ligase; Validated; Region: PRK06710
1034836007899	Prokaryotic long-chain fatty acid CoA synthetases similar to Escherichia coli FadD; Region: FC-FACS_FadD_like; cd05936
1034836007900	acyl-activating enzyme (AAE) consensus motif; other site
1034836007901	putative AMP binding site [chemical binding]; other site
1034836007902	putative active site [active]
1034836007903	putative CoA binding site [chemical binding]; other site
1034836007904	Protein of unknown function (DUF2711); Region: DUF2711; pfam10924
1034836007905	Predicted membrane protein [Function unknown]; Region: COG3766
1034836007906	Domain of Unknown Function (DUF350); Region: DUF350; pfam03994
1034836007907	Domain of Unknown Function (DUF350); Region: DUF350; pfam03994
1034836007908	recombination and DNA strand exchange inhibitor protein; Reviewed; Region: PRK00409
1034836007909	MutS domain III; Region: MutS_III; pfam05192
1034836007910	ATP-binding cassette domain of MutS2; Region: ABC_MutS2; cd03280
1034836007911	Walker A/P-loop; other site
1034836007912	ATP binding site [chemical binding]; other site
1034836007913	Q-loop/lid; other site
1034836007914	ABC transporter signature motif; other site
1034836007915	Walker B; other site
1034836007916	D-loop; other site
1034836007917	H-loop/switch region; other site
1034836007918	Smr domain; Region: Smr; pfam01713
1034836007919	hypothetical protein; Provisional; Region: PRK08609
1034836007920	Nucleotidyltransferase (NT) domain of family X DNA Polymerases; Region: NT_POLXc; cd00141
1034836007921	active site
1034836007922	primer binding site [nucleotide binding]; other site
1034836007923	NTP  binding site [chemical binding]; other site
1034836007924	metal binding triad [ion binding]; metal-binding site
1034836007925	Polymerase and Histidinol Phosphatase domain of bacterial polymerase X; Region: PHP_PolX; cd07436
1034836007926	active site
1034836007927	Uncharacterized membrane protein, required for colicin V production [General function prediction only]; Region: CvpA; COG1286
1034836007928	Colicin V production protein; Region: Colicin_V; pfam02674
1034836007929	cell division protein ZapA; Provisional; Region: PRK14126
1034836007930	ribonuclease HIII; Provisional; Region: PRK00996
1034836007931	Domain of unknown function (DUF3378); Region: DUF3378; pfam11858
1034836007932	bacterial Ribonuclease HIII-like; Region: RNase_HII_bacteria_HIII_like; cd06590
1034836007933	RNA/DNA hybrid binding site [nucleotide binding]; other site
1034836007934	active site
1034836007935	phenylalanyl-tRNA synthetase subunit beta; Reviewed; Region: pheT; PRK00629
1034836007936	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
1034836007937	putative tRNA-binding site [nucleotide binding]; other site
1034836007938	B3/4 domain; Region: B3_4; pfam03483
1034836007939	tRNA synthetase B5 domain; Region: B5; smart00874
1034836007940	Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA,  PheRS is an...; Region: PheRS_beta_core; cd00769
1034836007941	dimer interface [polypeptide binding]; other site
1034836007942	motif 1; other site
1034836007943	motif 3; other site
1034836007944	motif 2; other site
1034836007945	Ferredoxin-fold anticodon binding domain; Region: FDX-ACB; pfam03147
1034836007946	phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488
1034836007947	Aminoacyl tRNA synthetase class II, N-terminal domain; Region: Phe_tRNA-synt_N; pfam02912
1034836007948	Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496
1034836007949	dimer interface [polypeptide binding]; other site
1034836007950	motif 1; other site
1034836007951	active site
1034836007952	motif 2; other site
1034836007953	motif 3; other site
1034836007954	rRNA methylases [Translation, ribosomal structure and biogenesis]; Region: SpoU; COG0566
1034836007955	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; smart00967
1034836007956	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
1034836007957	small acid-soluble spore protein SspI; Provisional; Region: PRK02955
1034836007958	Sugar diacid utilization regulator [Transcription / Signal transduction mechanisms]; Region: CdaR; COG3835
1034836007959	Putative sugar diacid recognition; Region: Diacid_rec; pfam05651
1034836007960	PucR C-terminal helix-turn-helix domain; Region: HTH_30; pfam13556
1034836007961	FAD binding domain; Region: FAD_binding_4; pfam01565
1034836007962	glycolate oxidase, subunit GlcD; Region: glcD; TIGR00387
1034836007963	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1034836007964	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
1034836007965	Cysteine-rich domain; Region: CCG; pfam02754
1034836007966	Cysteine-rich domain; Region: CCG; pfam02754
1034836007967	Carbon starvation protein, predicted membrane protein [Signal transduction mechanisms]; Region: CstA; COG1966
1034836007968	Carbon starvation protein CstA; Region: CstA; pfam02554
1034836007969	C-terminal domain on CstA (DUF4161); Region: DUF4161; pfam13722
1034836007970	Alpha-L-arabinofuranosidase [Carbohydrate transport and metabolism]; Region: AbfA; COG3534
1034836007971	Alpha-L-arabinofuranosidase C-terminus; Region: Alpha-L-AF_C; pfam06964
1034836007972	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1034836007973	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1034836007974	dimer interface [polypeptide binding]; other site
1034836007975	conserved gate region; other site
1034836007976	putative PBP binding loops; other site
1034836007977	ABC-ATPase subunit interface; other site
1034836007978	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1034836007979	dimer interface [polypeptide binding]; other site
1034836007980	conserved gate region; other site
1034836007981	putative PBP binding loops; other site
1034836007982	ABC-ATPase subunit interface; other site
1034836007983	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
1034836007984	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
1034836007985	Glycerol-1-phosphate dehydrogenase (G1PDH) catalyzes the reversible reduction of dihydroxyacetone phosphate (DHAP) to glycerol-1-phosphate (G1P) in an NADH-dependent manner; Region: G1PDH; cd08175
1034836007986	Glycerol dehydrogenase and related enzymes [Energy production and conversion]; Region: GldA; COG0371
1034836007987	active site
1034836007988	metal binding site [ion binding]; metal-binding site
1034836007989	Predicted sugar phosphatases of the HAD superfamily [Carbohydrate transport and metabolism]; Region: NagD; COG0647
1034836007990	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1034836007991	active site
1034836007992	motif I; other site
1034836007993	motif II; other site
1034836007994	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1034836007995	motif II; other site
1034836007996	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
1034836007997	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
1034836007998	intersubunit interface [polypeptide binding]; other site
1034836007999	active site
1034836008000	Zn2+ binding site [ion binding]; other site
1034836008001	ribulokinase; Provisional; Region: PRK04123
1034836008002	Ribulokinases; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_RBK; cd07781
1034836008003	N- and C-terminal domain interface [polypeptide binding]; other site
1034836008004	active site
1034836008005	MgATP binding site [chemical binding]; other site
1034836008006	catalytic site [active]
1034836008007	metal binding site [ion binding]; metal-binding site
1034836008008	carbohydrate binding site [chemical binding]; other site
1034836008009	homodimer interface [polypeptide binding]; other site
1034836008010	L-arabinose isomerase; Provisional; Region: PRK02929
1034836008011	L-Arabinose isomerase (AI) catalyzes the isomerization of L-arabinose to L-ribulose, the first reaction in its conversion into D-xylulose-5-phosphate, an intermediate in the pentose phosphate pathway, which allows L-arabinose to be used as a carbon...; Region: L-arabinose_isomerase; cd03557
1034836008012	putative hexamer (dimer of trimers) interface [polypeptide binding]; other site
1034836008013	trimer interface [polypeptide binding]; other site
1034836008014	putative substrate binding site [chemical binding]; other site
1034836008015	putative metal binding site [ion binding]; other site
1034836008016	Glycosyl hydrolase family 43; Region: GH43_ABN; cd08988
1034836008017	substrate binding site [chemical binding]; other site
1034836008018	active site
1034836008019	Cellulase M and related proteins [Carbohydrate transport and metabolism]; Region: FrvX; COG1363
1034836008020	M42 Peptidase, Endoglucanases; Region: M42_Frv; cd05656
1034836008021	oligomer interface [polypeptide binding]; other site
1034836008022	active site
1034836008023	metal binding site [ion binding]; metal-binding site
1034836008024	Protein of unknown function (DUF1294); Region: DUF1294; cl01311
1034836008025	Ribosomal protein L20; Region: Ribosomal_L20; cd07026
1034836008026	23S rRNA binding site [nucleotide binding]; other site
1034836008027	L21 binding site [polypeptide binding]; other site
1034836008028	L13 binding site [polypeptide binding]; other site
1034836008029	translation initiation factor IF-3; Reviewed; Region: infC; PRK00028
1034836008030	Translation initiation factor IF-3, N-terminal domain; Region: IF3_N; pfam05198
1034836008031	Translation initiation factor IF-3, C-terminal domain; Region: IF3_C; pfam00707
1034836008032	antiholin-like protein LrgB; Provisional; Region: PRK04288
1034836008033	murein hydrolase regulator LrgA; Provisional; Region: PRK04125
1034836008034	two-component response regulator; Provisional; Region: PRK14084
1034836008035	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1034836008036	active site
1034836008037	phosphorylation site [posttranslational modification]
1034836008038	intermolecular recognition site; other site
1034836008039	dimerization interface [polypeptide binding]; other site
1034836008040	LytTr DNA-binding domain; Region: LytTR; smart00850
1034836008041	Putative regulator of cell autolysis [Signal transduction mechanisms]; Region: LytS; COG3275
1034836008042	5TMR of 5TMR-LYT; Region: 5TM-5TMR_LYT; pfam07694
1034836008043	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
1034836008044	Histidine kinase; Region: His_kinase; pfam06580
1034836008045	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1034836008046	ATP binding site [chemical binding]; other site
1034836008047	Mg2+ binding site [ion binding]; other site
1034836008048	G-X-G motif; other site
1034836008049	Predicted hydrolase (HAD superfamily) [General function prediction only]; Region: COG1011
1034836008050	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1034836008051	motif II; other site
1034836008052	threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK00413
1034836008053	TGS _ThrRS_N:  ThrRS (threonyl-tRNA Synthetase)  is a class II tRNA synthetase that couples threonine to its cognate tRNA.  In addition to its catalytic and anticodon-binding domains, ThrRS has an N-terminal TGS domain, named after the ThrRS, GTPase, and...; Region: TGS_ThrRS_N; cd01667
1034836008054	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
1034836008055	Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771
1034836008056	active site
1034836008057	dimer interface [polypeptide binding]; other site
1034836008058	motif 1; other site
1034836008059	motif 2; other site
1034836008060	motif 3; other site
1034836008061	ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860
1034836008062	anticodon binding site; other site
1034836008063	SAM dependent carboxyl methyltransferase; Region: Methyltransf_7; cl04109
1034836008064	YtxC-like family; Region: YtxC; pfam08812
1034836008065	Uncharacterized conserved protein [Function unknown]; Region: COG0398
1034836008066	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
1034836008067	primosomal protein DnaI; Reviewed; Region: PRK08939
1034836008068	Primosomal protein DnaI N-terminus; Region: DnaI_N; pfam07319
1034836008069	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1034836008070	Walker A motif; other site
1034836008071	ATP binding site [chemical binding]; other site
1034836008072	Walker B motif; other site
1034836008073	Replication initiation/membrane attachment protein [DNA replication, recombination, and repair]; Region: DnaB; COG3611
1034836008074	Replication initiation and membrane attachment; Region: DnaB_2; pfam07261
1034836008075	transcriptional regulator NrdR; Validated; Region: nrdR; PRK00464
1034836008076	ATP cone domain; Region: ATP-cone; pfam03477
1034836008077	S-adenosylmethionine decarboxylase proenzyme; Provisional; Region: PRK03124
1034836008078	glyceraldehyde-3-phosphate dehydrogenase; Validated; Region: PRK07729
1034836008079	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; pfam00044
1034836008080	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
1034836008081	Predicted transcriptional regulators [Transcription]; Region: COG1733
1034836008082	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
1034836008083	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
1034836008084	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1034836008085	putative substrate translocation pore; other site
1034836008086	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1034836008087	active site
1034836008088	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1034836008089	catalytic tetrad [active]
1034836008090	dephospho-CoA kinase; Region: TIGR00152
1034836008091	Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022
1034836008092	CoA-binding site [chemical binding]; other site
1034836008093	ATP-binding [chemical binding]; other site
1034836008094	putative sporulation protein YtaF; Region: spore_YtaF; TIGR02840
1034836008095	formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA glycosylase; Validated; Region: PRK01103
1034836008096	N-terminal domain of Escherichia coli Fpg1/MutM and related bacterial DNA glycosylases; Region: EcFpg-like_N; cd08966
1034836008097	DNA binding site [nucleotide binding]
1034836008098	catalytic residue [active]
1034836008099	H2TH interface [polypeptide binding]; other site
1034836008100	putative catalytic residues [active]
1034836008101	turnover-facilitating residue; other site
1034836008102	intercalation triad [nucleotide binding]; other site
1034836008103	8OG recognition residue [nucleotide binding]; other site
1034836008104	putative reading head residues; other site
1034836008105	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
1034836008106	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
1034836008107	DNA polymerase I; Provisional; Region: PRK05755
1034836008108	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
1034836008109	active site
1034836008110	metal binding site 1 [ion binding]; metal-binding site
1034836008111	putative 5' ssDNA interaction site; other site
1034836008112	metal binding site 3; metal-binding site
1034836008113	metal binding site 2 [ion binding]; metal-binding site
1034836008114	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
1034836008115	putative DNA binding site [nucleotide binding]; other site
1034836008116	putative metal binding site [ion binding]; other site
1034836008117	inactive DEDDy 3'-5' exonuclease domain of Bacillus stearothermophilus DNA polymerase I and similar family-A DNA polymerases; Region: DNA_polA_I_Bacillus_like_exo; cd06140
1034836008118	Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A_pol_I_C; cd08637
1034836008119	active site
1034836008120	DNA binding site [nucleotide binding]
1034836008121	catalytic site [active]
1034836008122	phosphate regulon sensor kinase PhoR; Region: phoR_proteo; TIGR02966
1034836008123	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1034836008124	putative active site [active]
1034836008125	heme pocket [chemical binding]; other site
1034836008126	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1034836008127	dimer interface [polypeptide binding]; other site
1034836008128	phosphorylation site [posttranslational modification]
1034836008129	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1034836008130	ATP binding site [chemical binding]; other site
1034836008131	Mg2+ binding site [ion binding]; other site
1034836008132	G-X-G motif; other site
1034836008133	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1034836008134	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1034836008135	active site
1034836008136	phosphorylation site [posttranslational modification]
1034836008137	intermolecular recognition site; other site
1034836008138	dimerization interface [polypeptide binding]; other site
1034836008139	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1034836008140	DNA binding site [nucleotide binding]
1034836008141	malate dehydrogenase; Reviewed; Region: PRK06223
1034836008142	L-lactate dehydrogenase-like malate dehydrogenase proteins; Region: LDH-like_MDH; cd01339
1034836008143	NAD(P) binding site [chemical binding]; other site
1034836008144	dimer interface [polypeptide binding]; other site
1034836008145	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1034836008146	substrate binding site [chemical binding]; other site
1034836008147	isocitrate dehydrogenase; Reviewed; Region: PRK07006
1034836008148	isocitrate dehydrogenase; Validated; Region: PRK07362
1034836008149	Bacillus subtilis (Bs) citrate synthase (CS)-II_like. CS catalyzes the condensation of acetyl coenzyme A (AcCoA) and oxalacetate (OAA) to form citrate and coenzyme A (CoA), the first step in the citric acid cycle (TCA or Krebs cycle). 2MCS catalyzes the...; Region: BSuCS-II_like; cd06110
1034836008150	dimer interface [polypeptide binding]; other site
1034836008151	Citrate synthase; Region: Citrate_synt; pfam00285
1034836008152	active site
1034836008153	citrylCoA binding site [chemical binding]; other site
1034836008154	oxalacetate/citrate binding site [chemical binding]; other site
1034836008155	coenzyme A binding site [chemical binding]; other site
1034836008156	catalytic triad [active]
1034836008157	Protein of unknown function (DUF441); Region: DUF441; pfam04284
1034836008158	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; cl00465
1034836008159	Domain of unknown function DUF20; Region: UPF0118; pfam01594
1034836008160	phage T7 F exclusion suppressor FxsA; Reviewed; Region: fxsA; PRK11463
1034836008161	pyruvate kinase; Provisional; Region: PRK06354
1034836008162	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cl17342
1034836008163	domain interfaces; other site
1034836008164	active site
1034836008165	Phosphohistidine swiveling domain [Signal transduction mechanisms]; Region: COG3848
1034836008166	Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include bacterial ATP-dependent...; Region: Bacterial_PFK; cd00763
1034836008167	6-phosphofructokinase; Region: PFKA_ATP; TIGR02482
1034836008168	active site
1034836008169	ADP/pyrophosphate binding site [chemical binding]; other site
1034836008170	dimerization interface [polypeptide binding]; other site
1034836008171	allosteric effector site; other site
1034836008172	fructose-1,6-bisphosphate binding site; other site
1034836008173	acetyl-CoA carboxylase carboxyltransferase subunit alpha; Validated; Region: PRK05724
1034836008174	acetyl-CoA carboxylase carboxyltransferase alpha subunit; Provisional; Region: accA; CHL00198
1034836008175	acetyl-CoA carboxylase subunit beta; Validated; Region: PRK05654
1034836008176	RNA polymerases M/15 Kd subunit; Region: RNA_POL_M_15KD; cl02717
1034836008177	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682
1034836008178	Malic enzyme [Energy production and conversion]; Region: SfcA; COG0281
1034836008179	Malic enzyme, N-terminal domain; Region: malic; pfam00390
1034836008180	NAD(P) binding domain of malic enzyme (ME), subgroup 2; Region: NAD_bind_2_malic_enz; cd05311
1034836008181	putative NAD(P) binding site [chemical binding]; other site
1034836008182	DNA polymerase III DnaE; Reviewed; Region: dnaE; PRK06920
1034836008183	Polymerase and Histidinol Phosphatase domain; Region: PHP; cl17102
1034836008184	active site
1034836008185	DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485
1034836008186	generic binding surface I; other site
1034836008187	generic binding surface II; other site
1034836008188	Sporulation protein YtrH; Region: Spore_YtrH; pfam14034
1034836008189	Exopolyphosphatase-related proteins [General function prediction only]; Region: COG0618
1034836008190	DHH family; Region: DHH; pfam01368
1034836008191	DHHA1 domain; Region: DHHA1; pfam02272
1034836008192	YtpI-like protein; Region: YtpI; pfam14007
1034836008193	Predicted transcriptional regulator containing CBS domains [Transcription]; Region: COG4109
1034836008194	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1034836008195	DNA-binding site [nucleotide binding]; DNA binding site
1034836008196	DRTGG domain; Region: DRTGG; pfam07085
1034836008197	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with a DRTGG domain upstream. The function of the DRTGG domain, named after its conserved residues, is unknown. CBS is a small domain originally...; Region: CBS_pair_DRTGG_assoc; cd04596
1034836008198	The hotdog fold was initially identified in the E. coli FabA (beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase) structure and subsequently in 4HBT (4-hydroxybenzoyl-CoA thioesterase) from Pseudomonas. A number of other seemingly unrelated...; Region: hot_dog; cd03440
1034836008199	active site 2 [active]
1034836008200	active site 1 [active]
1034836008201	metal-dependent hydrolase; Provisional; Region: PRK00685
1034836008202	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
1034836008203	3-ketoacyl-(acyl-carrier-protein) reductase; Provisional; Region: fabG; PRK12825
1034836008204	classical (c) SDRs; Region: SDR_c; cd05233
1034836008205	NAD(P) binding site [chemical binding]; other site
1034836008206	active site
1034836008207	argininosuccinate lyase; Provisional; Region: PRK00855
1034836008208	Argininosuccinate lyase (argininosuccinase, ASAL); Region: Argininosuccinate_lyase; cd01359
1034836008209	active sites [active]
1034836008210	tetramer interface [polypeptide binding]; other site
1034836008211	argininosuccinate synthase; Provisional; Region: PRK13820
1034836008212	Argininosuccinate synthase. The Argininosuccinate synthase is a urea cycle enzyme that catalyzes the penultimate step in arginine biosynthesis: the ATP-dependent ligation of citrulline to aspartate to form argininosuccinate, AMP and pyrophosphate .  In...; Region: Argininosuccinate_Synthase; cd01999
1034836008213	ANP binding site [chemical binding]; other site
1034836008214	Substrate Binding Site II [chemical binding]; other site
1034836008215	Substrate Binding Site I [chemical binding]; other site
1034836008216	MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea; Region: MogA_MoaB; cd00886
1034836008217	MPT binding site; other site
1034836008218	trimer interface [polypeptide binding]; other site
1034836008219	acetate kinase A/propionate kinase 2; Reviewed; Region: PRK00180
1034836008220	propionate/acetate kinase; Provisional; Region: PRK12379
1034836008221	Adenine-specific DNA methylase [DNA replication, recombination, and repair]; Region: COG0827
1034836008222	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1034836008223	S-adenosylmethionine binding site [chemical binding]; other site
1034836008224	Peroxiredoxin (PRX) family, Atypical 2-cys PRX subfamily; composed of PRXs containing peroxidatic and resolving cysteines, similar to the homodimeric thiol specific antioxidant (TSA) protein also known as TRX-dependent thiol peroxidase (Tpx). Tpx is a...; Region: PRX_Atyp2cys; cd03014
1034836008225	dimer interface [polypeptide binding]; other site
1034836008226	catalytic triad [active]
1034836008227	peroxidatic and resolving cysteines [active]
1034836008228	sporulation protein YtfJ; Region: spore_ytfJ; TIGR02874
1034836008229	Protein of unknown function (DUF2953); Region: DUF2953; pfam11167
1034836008230	RDD family; Region: RDD; pfam06271
1034836008231	signal peptide peptidase SppA, 36K type; Region: SppA_dom; TIGR00706
1034836008232	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_N_C; cd07023
1034836008233	tandem repeat interface [polypeptide binding]; other site
1034836008234	oligomer interface [polypeptide binding]; other site
1034836008235	active site residues [active]
1034836008236	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK03501
1034836008237	ATP-NAD kinase; Region: NAD_kinase; pfam01513
1034836008238	Predicted metal-dependent hydrolase with the TIM-barrel fold [General function prediction only]; Region: COG1574
1034836008239	YtcJ_like metal dependent amidohydrolases. YtcJ is a Bacillus subtilis ORF of unknown function. The Arabidopsis homolog LAF3 has been identified as a factor required for photochrome A signalling; Region: YtcJ_like; cd01300
1034836008240	active site
1034836008241	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1034836008242	Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases [Lipid metabolism]; Region: Acs; COG0365
1034836008243	Medium-chain acyl-CoA synthetase (MACS or ACSM); Region: MACS_like; cd05972
1034836008244	active site
1034836008245	acyl-activating enzyme (AAE) consensus motif; other site
1034836008246	putative CoA binding site [chemical binding]; other site
1034836008247	AMP binding site [chemical binding]; other site
1034836008248	Small, acid-soluble spore proteins, alpha/beta type; Region: SASP; pfam00269
1034836008249	thiamine biosynthesis protein ThiI; Provisional; Region: PRK01565
1034836008250	THUMP domain of thiamine biosynthesis protein ThiI; Region: THUMP_ThiI; cd11716
1034836008251	ThiI is required for thiazole synthesis in the thiamine biosynthesis pathway. It belongs to the Adenosine Nucleotide Hydrolysis suoerfamily and predicted to bind to Adenosine nucleotide; Region: ThiI; cd01712
1034836008252	Ligand Binding Site [chemical binding]; other site
1034836008253	Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism]; Region: NifS; COG1104
1034836008254	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
1034836008255	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1034836008256	catalytic residue [active]
1034836008257	Branched-chain amino acid transport protein; Region: Branch_AA_trans; pfam05525
1034836008258	Septation ring formation regulator, EzrA; Region: EzrA; pfam06160
1034836008259	TMPIT-like protein; Region: TMPIT; pfam07851
1034836008260	histidinol-phosphatase; Reviewed; Region: PRK08123
1034836008261	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase of Hisj like; Region: PHP_HisPPase_Hisj_like; cd12110
1034836008262	active site
1034836008263	dimer interface [polypeptide binding]; other site
1034836008264	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1034836008265	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1034836008266	GAF domain-containing protein [Signal transduction mechanisms]; Region: COG1956
1034836008267	GAF domain; Region: GAF_2; pfam13185
1034836008268	GAF domain; Region: GAF_3; pfam13492
1034836008269	GAF domain; Region: GAF_2; pfam13185
1034836008270	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1034836008271	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1034836008272	metal binding site [ion binding]; metal-binding site
1034836008273	active site
1034836008274	I-site; other site
1034836008275	30S ribosomal protein S4; Validated; Region: rpsD; PRK05327
1034836008276	Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163
1034836008277	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1034836008278	RNA binding surface [nucleotide binding]; other site
1034836008279	bifunctional nitric oxide dioxygenase/dihydropteridine reductase 2; Provisional; Region: PRK13289
1034836008280	Globins are heme proteins, which bind and transport oxygen. This family summarizes a diverse set of homologous protein domains, including: (1) tetrameric vertebrate hemoglobins, which are the major protein component of erythrocytes and transport oxygen...; Region: globin; cd01040
1034836008281	heme-binding site [chemical binding]; other site
1034836008282	FAD_NAD(P)H binding domain of flavohemoglobin. Flavohemoglobins have a globin domain containing a B-type heme fused with a ferredoxin reductase-like FAD/NAD-binding domain. Flavohemoglobins detoxify nitric oxide (NO) via an NO dioxygenase reaction. The...; Region: flavohem_like_fad_nad_binding; cd06184
1034836008283	FAD binding pocket [chemical binding]; other site
1034836008284	FAD binding motif [chemical binding]; other site
1034836008285	phosphate binding motif [ion binding]; other site
1034836008286	beta-alpha-beta structure motif; other site
1034836008287	NAD binding pocket [chemical binding]; other site
1034836008288	Heme binding  pocket [chemical binding]; other site
1034836008289	Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GAT_1; cl00020
1034836008290	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cd00229
1034836008291	active site
1034836008292	catalytic triad [active]
1034836008293	oxyanion hole [active]
1034836008294	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
1034836008295	cation diffusion facilitator family transporter; Region: CDF; TIGR01297
1034836008296	Predicted transcriptional regulators [Transcription]; Region: COG1378
1034836008297	Sugar-specific transcriptional regulator TrmB; Region: TrmB; pfam01978
1034836008298	Middle phospholipase D-like domain of the transcriptional regulator TrmB and similar proteins; Region: PLDc_like_TrmB_middle; cd09124
1034836008299	C-terminal domain interface [polypeptide binding]; other site
1034836008300	sugar binding site [chemical binding]; other site
1034836008301	Predicted branched-chain amino acid permease (azaleucine resistance) [Amino acid transport and metabolism]; Region: AzlC; COG1296
1034836008302	Branched-chain amino acid transport protein (AzlD); Region: AzlD; pfam05437
1034836008303	tyrosyl-tRNA synthetase; Validated; Region: PRK05912
1034836008304	catalytic core domain of tyrosinyl-tRNA and tryptophanyl-tRNA synthetase; Region: Tyr_Trp_RS_core; cd00395
1034836008305	active site
1034836008306	HIGH motif; other site
1034836008307	dimer interface [polypeptide binding]; other site
1034836008308	KMSKS motif; other site
1034836008309	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1034836008310	RNA binding surface [nucleotide binding]; other site
1034836008311	acetyl-CoA synthetase; Provisional; Region: PRK04319
1034836008312	Domain of unknown function (DUF3448); Region: DUF3448; pfam11930
1034836008313	Uncharacterized subfamily of Acetyl-CoA synthetase like family (ACS); Region: MACS_like_4; cd05969
1034836008314	active site
1034836008315	acyl-activating enzyme (AAE) consensus motif; other site
1034836008316	putative CoA binding site [chemical binding]; other site
1034836008317	AMP binding site [chemical binding]; other site
1034836008318	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1034836008319	Coenzyme A binding pocket [chemical binding]; other site
1034836008320	FOG: CBS domain [General function prediction only]; Region: COG0517
1034836008321	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in  the acetoin utilization proteins in bacteria. Acetoin is a product of fermentative metabolism in many prokaryotic and eukaryotic microorganisms.  They produce...; Region: CBS_pair_ACT_assoc; cd04584
1034836008322	C-terminal ACT domain of the Bacillus subtilis acetoin utilization protein, AcuB; Region: ACT_AcuB; cd04883
1034836008323	Deacetylases, including yeast histone deacetylase and acetoin utilization protein [Chromatin structure and dynamics / Secondary metabolites biosynthesis, transport, and catabolism]; Region: AcuC; COG0123
1034836008324	Class I histone deacetylase AcuC (Acetoin utilization protein)-like enzymes; Region: HDAC_AcuC_like; cd09994
1034836008325	active site
1034836008326	Zn binding site [ion binding]; other site
1034836008327	flagellar motor protein MotS; Reviewed; Region: PRK06925
1034836008328	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1034836008329	ligand binding site [chemical binding]; other site
1034836008330	flagellar motor protein MotP; Reviewed; Region: PRK06926
1034836008331	MotA/TolQ/ExbB proton channel family; Region: MotA_ExbB; cl00568
1034836008332	catabolite control protein A; Region: ccpA; TIGR01481
1034836008333	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1034836008334	DNA binding site [nucleotide binding]
1034836008335	domain linker motif; other site
1034836008336	Ligand-binding domain of the catabolite control protein A (CcpA), which functions as the major transcriptional regulator of carbon catabolite repression/regulation; Region: PBP1_CcpA_like; cd06298
1034836008337	dimerization interface [polypeptide binding]; other site
1034836008338	effector binding site; other site
1034836008339	bifunctional 3-deoxy-7-phosphoheptulonate synthase/chorismate mutase; Reviewed; Region: PRK12595
1034836008340	Chorismate mutase type II; Region: CM_2; cl00693
1034836008341	phospho-2-dehydro-3-deoxyheptonate aldolase; Region: DAHP_synth_Bsub; TIGR01361
1034836008342	Protein of unknown function (DUF2847); Region: DUF2847; pfam11009
1034836008343	Gas vesicle protein [General function prediction only]; Region: GvpP; COG4980
1034836008344	Uncharacterized protein containing a divergent version of the methyl-accepting chemotaxis-like domain [General function prediction only]; Region: COG4768
1034836008345	UDP-N-acetylmuramate--L-alanine ligase; Provisional; Region: murC; PRK00421
1034836008346	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1034836008347	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1034836008348	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1034836008349	DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell division and chromosome partitioning]; Region: FtsK; COG1674
1034836008350	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
1034836008351	This domain directs oriented DNA translocation and forms a winged helix structure; Region: Ftsk_gamma; smart00843
1034836008352	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
1034836008353	putative tRNA-binding site [nucleotide binding]; other site
1034836008354	hypothetical protein; Provisional; Region: PRK13668
1034836008355	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
1034836008356	catalytic residues [active]
1034836008357	YtoQ family protein; Region: YtoQ_fam; TIGR03646
1034836008358	Cellulase M and related proteins [Carbohydrate transport and metabolism]; Region: FrvX; COG1363
1034836008359	M42 Peptidase, Endoglucanases; Region: M42_Frv; cd05656
1034836008360	oligomer interface [polypeptide binding]; other site
1034836008361	active site
1034836008362	metal binding site [ion binding]; metal-binding site
1034836008363	Predicted small secreted protein [Function unknown]; Region: COG5584
1034836008364	malate dehydrogenase; Provisional; Region: PRK13529
1034836008365	Adenine nucleotide alpha hydrolases superfamily including N type ATP PPases, ATP sulphurylases Universal Stress Response protein and electron transfer flavoprotein (ETF). The domain forms a apha/beta/apha fold which  binds to Adenosine nucleotide; Region: AANH_like; cl00292
1034836008366	Malic enzyme, N-terminal domain; Region: malic; pfam00390
1034836008367	NAD(P) binding domain of malic enzyme (ME), subgroup 1; Region: NAD_bind_1_malic_enz; cd05312
1034836008368	NAD(P) binding site [chemical binding]; other site
1034836008369	Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491
1034836008370	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1034836008371	S-adenosylmethionine binding site [chemical binding]; other site
1034836008372	YtzH-like protein; Region: YtzH; pfam14165
1034836008373	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cd05120
1034836008374	active site
1034836008375	ATP binding site [chemical binding]; other site
1034836008376	Phosphotransferase enzyme family; Region: APH; pfam01636
1034836008377	substrate binding site [chemical binding]; other site
1034836008378	lipid kinase, YegS/Rv2252/BmrU family; Region: TIGR00147
1034836008379	Diacylglycerol kinase catalytic domain; Region: DAGK_cat; pfam00781
1034836008380	2'-5' RNA ligase; Region: 2_5_ligase; TIGR02258
1034836008381	LigT like Phosphoesterase; Region: LigT_PEase; pfam02834
1034836008382	LigT like Phosphoesterase; Region: LigT_PEase; pfam02834
1034836008383	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
1034836008384	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
1034836008385	dimer interface [polypeptide binding]; other site
1034836008386	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1034836008387	catalytic residue [active]
1034836008388	dipeptidase PepV; Reviewed; Region: PRK07318
1034836008389	M20 Peptidase Xaa-His dipeptidase (PepV) degrades hydrophobic dipeptides; Region: M20_PepV; cd03888
1034836008390	active site
1034836008391	metal binding site [ion binding]; metal-binding site
1034836008392	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
1034836008393	Bacterial ABC transporter protein EcsB; Region: EcsB; cl11542
1034836008394	ABC-type Na+ transport system, ATPase component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatA; COG4555
1034836008395	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1034836008396	Walker A/P-loop; other site
1034836008397	ATP binding site [chemical binding]; other site
1034836008398	Q-loop/lid; other site
1034836008399	ABC transporter signature motif; other site
1034836008400	Walker B; other site
1034836008401	D-loop; other site
1034836008402	H-loop/switch region; other site
1034836008403	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; cl17531
1034836008404	16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187
1034836008405	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1034836008406	RNA binding surface [nucleotide binding]; other site
1034836008407	Pseudouridine synthase, Escherichia coli RsuA like; Region: PseudoU_synth_RsuA; cd02553
1034836008408	active site
1034836008409	uracil binding [chemical binding]; other site
1034836008410	stage V sporulation protein B; Region: spore_V_B; TIGR02900
1034836008411	Stage V sporulation protein B, also known as Stage III sporulation protein F, and related proteins; Region: MATE_SpoVB_like; cd13124
1034836008412	HI0933-like protein; Region: HI0933_like; pfam03486
1034836008413	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1034836008414	BCCT family transporter; Region: BCCT; pfam02028
1034836008415	Protein of unknown function (DUF2758); Region: DUF2758; pfam10957
1034836008416	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1034836008417	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1034836008418	DNA binding site [nucleotide binding]
1034836008419	domain linker motif; other site
1034836008420	Ligand-binding domain of DNA transcription repressor GalR which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalR; cd01544
1034836008421	putative ligand binding site [chemical binding]; other site
1034836008422	putative dimerization interface [polypeptide binding]; other site
1034836008423	PBP superfamily domain; Region: PBP_like_2; cl17296
1034836008424	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
1034836008425	Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416
1034836008426	ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism]; Region: LplB; COG4209
1034836008427	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1034836008428	dimer interface [polypeptide binding]; other site
1034836008429	conserved gate region; other site
1034836008430	putative PBP binding loops; other site
1034836008431	ABC-ATPase subunit interface; other site
1034836008432	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1034836008433	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1034836008434	dimer interface [polypeptide binding]; other site
1034836008435	conserved gate region; other site
1034836008436	putative PBP binding loops; other site
1034836008437	ABC-ATPase subunit interface; other site
1034836008438	alpha-galactosidase; Provisional; Region: PRK15076
1034836008439	Glycoside Hydrolases Family 4; Alpha-glucosidases and alpha-galactosidases; Region: GH4_alpha_glucosidase_galactosidase; cd05297
1034836008440	NAD binding site [chemical binding]; other site
1034836008441	sugar binding site [chemical binding]; other site
1034836008442	divalent metal binding site [ion binding]; other site
1034836008443	putative tetramer (dimer of dimers) interface [polypeptide binding]; other site
1034836008444	dimer interface [polypeptide binding]; other site
1034836008445	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
1034836008446	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1034836008447	Coenzyme A binding pocket [chemical binding]; other site
1034836008448	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
1034836008449	active site residue [active]
1034836008450	leucyl-tRNA synthetase; Validated; Region: leuS; PRK00390
1034836008451	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
1034836008452	HIGH motif; other site
1034836008453	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
1034836008454	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1034836008455	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
1034836008456	active site
1034836008457	KMSKS motif; other site
1034836008458	Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; Region: Anticodon_Ia_Leu_BEm; cd07958
1034836008459	tRNA binding surface [nucleotide binding]; other site
1034836008460	Protein of unknown function (DUF4257); Region: DUF4257; pfam14074
1034836008461	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1034836008462	PAS domain; Region: PAS_9; pfam13426
1034836008463	putative active site [active]
1034836008464	heme pocket [chemical binding]; other site
1034836008465	Sulphate Transporter and Anti-Sigma factor antagonist domain of the "stressosome" complex proteins RsbS and RsbR, regulators of the bacterial stress activated alternative sigma factor sigma-B by phosphorylation; Region: STAS_RsbR_RsbS_like; cd07041
1034836008466	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1034836008467	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1034836008468	putative substrate translocation pore; other site
1034836008469	Integral membrane protein (intg_mem_TP0381); Region: Intg_mem_TP0381; pfam09529
1034836008470	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
1034836008471	FtsX-like permease family; Region: FtsX; pfam02687
1034836008472	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1034836008473	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1034836008474	Walker A/P-loop; other site
1034836008475	ATP binding site [chemical binding]; other site
1034836008476	Q-loop/lid; other site
1034836008477	ABC transporter signature motif; other site
1034836008478	Walker B; other site
1034836008479	D-loop; other site
1034836008480	H-loop/switch region; other site
1034836008481	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1034836008482	dimer interface [polypeptide binding]; other site
1034836008483	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cl00080
1034836008484	phosphorylation site [posttranslational modification]
1034836008485	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1034836008486	ATP binding site [chemical binding]; other site
1034836008487	Mg2+ binding site [ion binding]; other site
1034836008488	G-X-G motif; other site
1034836008489	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1034836008490	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1034836008491	active site
1034836008492	phosphorylation site [posttranslational modification]
1034836008493	intermolecular recognition site; other site
1034836008494	dimerization interface [polypeptide binding]; other site
1034836008495	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1034836008496	DNA binding site [nucleotide binding]
1034836008497	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1034836008498	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
1034836008499	FtsX-like permease family; Region: FtsX; pfam02687
1034836008500	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1034836008501	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1034836008502	Walker A/P-loop; other site
1034836008503	ATP binding site [chemical binding]; other site
1034836008504	Q-loop/lid; other site
1034836008505	ABC transporter signature motif; other site
1034836008506	Walker B; other site
1034836008507	D-loop; other site
1034836008508	H-loop/switch region; other site
1034836008509	ABC-2 family transporter protein; Region: ABC2_membrane_2; cl17866
1034836008510	ABC-2 family transporter protein; Region: ABC2_membrane_2; cl17866
1034836008511	potential frameshift: common BLAST hit: gi|154687224|ref|YP_001422385.1| hypothetical protein RBAM_028220
1034836008512	Predicted transcriptional regulators [Transcription]; Region: COG1725
1034836008513	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1034836008514	DNA-binding site [nucleotide binding]; DNA binding site
1034836008515	Protein of unknown function (DUF2524); Region: DUF2524; pfam10732
1034836008516	Predicted Fe-S oxidoreductase [General function prediction only]; Region: COG1242
1034836008517	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1034836008518	S-adenosylmethionine binding site [chemical binding]; other site
1034836008519	Protein of unknown function (DUF2600); Region: DUF2600; pfam10776
1034836008520	Lysophospholipase [Lipid metabolism]; Region: PldB; COG2267
1034836008521	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
1034836008522	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
1034836008523	Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily [General function prediction only]; Region: PaaY; COG0663
1034836008524	Gamma carbonic anhydrase-like: This family is composed of gamma carbonic anhydrase (CA), Ferripyochelin Binding Protein (FBP), E. coli paaY protein, and similar proteins. CAs are zinc-containing enzymes that catalyze the reversible hydration of carbon...; Region: LbH_gamma_CA_like; cd04645
1034836008525	trimer interface [polypeptide binding]; other site
1034836008526	putative metal binding site [ion binding]; other site
1034836008527	Gamma-aminobutyrate permease and related permeases [Amino acid transport and metabolism]; Region: AnsP; COG1113
1034836008528	Spore germination protein; Region: Spore_permease; cl17796
1034836008529	Asparagine synthase (glutamine-hydrolyzing) [Amino acid transport and metabolism]; Region: AsnB; COG0367
1034836008530	Glutamine amidotransferases class-II (GATase) asparagine synthase_B type.  Asparagine synthetase B catalyses the ATP-dependent conversion of aspartate to asparagine. This enzyme is a homodimer, with each monomer composed of a  glutaminase domain and a...; Region: AsnB; cd00712
1034836008531	active site
1034836008532	dimer interface [polypeptide binding]; other site
1034836008533	The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B  catalyzes the...; Region: Asn_Synthase_B_C; cd01991
1034836008534	Ligand Binding Site [chemical binding]; other site
1034836008535	Molecular Tunnel; other site
1034836008536	S-adenosylmethionine synthetase; Validated; Region: PRK05250
1034836008537	S-adenosylmethionine synthetase, N-terminal domain; Region: S-AdoMet_synt_N; pfam00438
1034836008538	S-adenosylmethionine synthetase, central domain; Region: S-AdoMet_synt_M; pfam02772
1034836008539	S-adenosylmethionine synthetase, C-terminal domain; Region: S-AdoMet_synt_C; pfam02773
1034836008540	Phosphoenolpyruvate carboxykinase; Region: PEPCK_ATP; pfam01293
1034836008541	Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and...; Region: PEPCK_ATP; cd00484
1034836008542	active site
1034836008543	substrate-binding site [chemical binding]; other site
1034836008544	metal-binding site [ion binding]
1034836008545	ATP binding site [chemical binding]; other site
1034836008546	Protein of unknown function (DUF2584); Region: DUF2584; pfam10763
1034836008547	Dienelactone hydrolase family; Region: DLH; pfam01738
1034836008548	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1034836008549	ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components [Inorganic ion transport and metabolism]; Region: TauA; COG0715
1034836008550	NMT1-like family; Region: NMT1_2; pfam13379
1034836008551	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: TauB; COG1116
1034836008552	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
1034836008553	Walker A/P-loop; other site
1034836008554	ATP binding site [chemical binding]; other site
1034836008555	Q-loop/lid; other site
1034836008556	ABC transporter signature motif; other site
1034836008557	Walker B; other site
1034836008558	D-loop; other site
1034836008559	H-loop/switch region; other site
1034836008560	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
1034836008561	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1034836008562	dimer interface [polypeptide binding]; other site
1034836008563	conserved gate region; other site
1034836008564	putative PBP binding loops; other site
1034836008565	ABC-ATPase subunit interface; other site
1034836008566	nucleoside triphosphatase YtkD; Region: nudix_YtkD; TIGR02705
1034836008567	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_8; cd04665
1034836008568	nudix motif; other site
1034836008569	Phage-related holin (Lysis protein) [General function prediction only]; Region: COG4824
1034836008570	DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism]; Region: Dps; COG0783
1034836008571	DPS protein, ferritin-like diiron-binding domain; Region: DPS; cd01043
1034836008572	dimerization interface [polypeptide binding]; other site
1034836008573	DPS ferroxidase diiron center [ion binding]; other site
1034836008574	ion pore; other site
1034836008575	YtkA-like; Region: YtkA; pfam13115
1034836008576	S-ribosylhomocysteinase; Provisional; Region: PRK02260
1034836008577	Haemolytic domain; Region: Haemolytic; pfam01809
1034836008578	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeD; cd03379
1034836008579	active site clefts [active]
1034836008580	zinc binding site [ion binding]; other site
1034836008581	dimer interface [polypeptide binding]; other site
1034836008582	50S ribosomal protein L31 type B; Reviewed; Region: rpmE2; PRK01678
1034836008583	Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; pfam01654
1034836008584	Cytochrome bd-type quinol oxidase, subunit 2 [Energy production and conversion]; Region: AppB; COG1294
1034836008585	Domain of Unknown Function (DUF1540); Region: DUF1540; pfam07561
1034836008586	N-acylamino acid racemase (NAAAR), an octameric enzyme that catalyzes the racemization of N-acylamino acids. NAAARs act on a broad range of N-acylamino acids rather than amino acids. Enantiopure amino acids are of industrial interest as chiral building...; Region: NAAAR; cd03317
1034836008587	o-succinylbenzoate synthase; Region: menC_lowGC/arch; TIGR01928
1034836008588	active site
1034836008589	octamer interface [polypeptide binding]; other site
1034836008590	O-succinylbenzoic acid--CoA ligase; Provisional; Region: PRK03640
1034836008591	O-succinylbenzoate-CoA ligase (also known as O-succinylbenzoate-CoA synthase, OSB-CoA synthetase, or MenE); Region: OSB_CoA_lg; cd05912
1034836008592	acyl-activating enzyme (AAE) consensus motif; other site
1034836008593	putative AMP binding site [chemical binding]; other site
1034836008594	putative active site [active]
1034836008595	putative CoA binding site [chemical binding]; other site
1034836008596	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
1034836008597	Enoyl-CoA hydratase/isomerase family; Region: ECH; pfam00378
1034836008598	substrate binding site [chemical binding]; other site
1034836008599	oxyanion hole (OAH) forming residues; other site
1034836008600	trimer interface [polypeptide binding]; other site
1034836008601	2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase; Region: menH_SHCHC; TIGR03695
1034836008602	homoserine O-acetyltransferase; Provisional; Region: metX; cl17114
1034836008603	2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1- carboxylate synthase; Validated; Region: PRK07449
1034836008604	Pyrimidine (PYR) binding domain of 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexadiene-1- carboxylate synthase (MenD) and related proteins; Region: TPP_PYR_MenD; cd07037
1034836008605	dimer interface [polypeptide binding]; other site
1034836008606	tetramer interface [polypeptide binding]; other site
1034836008607	PYR/PP interface [polypeptide binding]; other site
1034836008608	TPP binding site [chemical binding]; other site
1034836008609	Thiamine pyrophosphate (TPP) family, SHCHC synthase subfamily, TPP-binding module; composed of proteins similar to Escherichia coli 2-succinyl-6-hydroxyl-2,4-cyclohexadiene-1-carboxylic acid (SHCHC) synthase (also called MenD). SHCHC synthase plays a key...; Region: TPP_SHCHC_synthase; cd02009
1034836008610	TPP-binding site; other site
1034836008611	Isochorismate synthase [Coenzyme metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: MenF; COG1169
1034836008612	chorismate binding enzyme; Region: Chorismate_bind; cl10555
1034836008613	regulatory protein, yteA family; Region: bacill_yteA; TIGR02890
1034836008614	TspO/MBR family; Region: TspO_MBR; pfam03073
1034836008615	Predicted membrane protein [Function unknown]; Region: COG3859
1034836008616	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2268
1034836008617	Band_7_flotillin: a subgroup of the band 7 domain of flotillin (reggie) like proteins. This subgroup contains proteins similar to stomatin, prohibitin, flotillin, HlfK/C and podicin.  These two proteins are lipid raft-associated.  Individual proteins of...; Region: Band_7_flotillin; cd03399
1034836008618	DinB superfamily; Region: DinB_2; pfam12867
1034836008619	DinB family; Region: DinB; cl17821
1034836008620	MOSC domain; Region: MOSC; pfam03473
1034836008621	Alcohol dehydrogenase, class IV [Energy production and conversion]; Region: EutG; COG1454
1034836008622	Dehydroquinate synthase-like (DHQ-like) and iron-containing alcohol dehydrogenases (Fe-ADH); Region: DHQ_Fe-ADH; cl02872
1034836008623	active site
1034836008624	NAD binding site [chemical binding]; other site
1034836008625	metal binding site [ion binding]; metal-binding site
1034836008626	Bacillus subtilis NAD+-dependent betaine aldehyde dehydrogenase-like; Region: ALDH_BADH-GbsA; cd07119
1034836008627	glycine betaine aldehyde dehydrogenase; Region: BADH; TIGR01804
1034836008628	tetramerization interface [polypeptide binding]; other site
1034836008629	NAD(P) binding site [chemical binding]; other site
1034836008630	catalytic residues [active]
1034836008631	Predicted transcriptional regulators [Transcription]; Region: COG1510
1034836008632	MarR family; Region: MarR_2; pfam12802
1034836008633	K+ transport systems, NAD-binding component [Inorganic ion transport and metabolism]; Region: TrkA; COG0569
1034836008634	TrkA-N domain; Region: TrkA_N; pfam02254
1034836008635	TrkA-C domain; Region: TrkA_C; pfam02080
1034836008636	Muramidase (flagellum-specific) [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FlgJ; COG1705
1034836008637	SH3-like domain; Region: SH3_8; pfam13457
1034836008638	bifunctional nitric oxide dioxygenase/dihydropteridine reductase 2; Provisional; Region: PRK13289
1034836008639	Globins are heme proteins, which bind and transport oxygen. This family summarizes a diverse set of homologous protein domains, including: (1) tetrameric vertebrate hemoglobins, which are the major protein component of erythrocytes and transport oxygen...; Region: globin; cd01040
1034836008640	heme-binding site [chemical binding]; other site
1034836008641	FAD_NAD(P)H binding domain of flavohemoglobin. Flavohemoglobins have a globin domain containing a B-type heme fused with a ferredoxin reductase-like FAD/NAD-binding domain. Flavohemoglobins detoxify nitric oxide (NO) via an NO dioxygenase reaction. The...; Region: flavohem_like_fad_nad_binding; cd06184
1034836008642	FAD binding pocket [chemical binding]; other site
1034836008643	FAD binding motif [chemical binding]; other site
1034836008644	phosphate binding motif [ion binding]; other site
1034836008645	beta-alpha-beta structure motif; other site
1034836008646	NAD binding pocket [chemical binding]; other site
1034836008647	Heme binding  pocket [chemical binding]; other site
1034836008648	Cupin domain; Region: Cupin_2; cl17218
1034836008649	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
1034836008650	binding surface
1034836008651	TPR motif; other site
1034836008652	Tetratricopeptide repeat; Region: TPR_12; pfam13424
1034836008653	Tetratricopeptide repeat; Region: TPR_12; pfam13424
1034836008654	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1034836008655	binding surface
1034836008656	TPR motif; other site
1034836008657	Cro/C1-type HTH DNA-binding domain; Region: HTH_26; pfam13443
1034836008658	Protein of unknown function (DUF1433); Region: DUF1433; pfam07252
1034836008659	D-alanyl-D-alanine carboxypeptidase; Region: Peptidase_M15_4; pfam13539
1034836008660	Phage uncharacterized protein (Phage_XkdX); Region: Phage_XkdX; cl09900
1034836008661	Domain of unknown function (DUF2479); Region: DUF2479; pfam10651
1034836008662	Pectate lyase superfamily protein; Region: Pectate_lyase_3; pfam12708
1034836008663	Peptidase_G2, IMC autoproteolytic cleavage domain; Region: Peptidase_G2; pfam11962
1034836008664	Prophage endopeptidase tail; Region: Prophage_tail; cl12123
1034836008665	Prophage endopeptidase tail; Region: Prophage_tail; cl12123
1034836008666	Phage tail protein; Region: Sipho_tail; pfam05709
1034836008667	Fibrinogen alpha/beta chain family; Region: Fib_alpha; pfam08702
1034836008668	Phage-related minor tail protein; Region: PhageMin_Tail; pfam10145
1034836008669	Phage-related protein [Function unknown]; Region: COG5412
1034836008670	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1034836008671	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1034836008672	catalytic residue [active]
1034836008673	phage major tail protein, phi13 family; Region: maj_tail_phi13; TIGR01603
1034836008674	phage protein, HK97 gp10 family; Region: phge_HK97_gp10; TIGR01725
1034836008675	Phage head-tail joining protein; Region: Phage_H_T_join; pfam05521
1034836008676	phage major capsid protein, HK97 family; Region: major_cap_HK97; TIGR01554
1034836008677	Phage capsid family; Region: Phage_capsid; pfam05065
1034836008678	Phage head maturation protease [General function prediction only]; Region: COG3740
1034836008679	Phage portal protein; Region: Phage_portal; pfam04860
1034836008680	Phage-related protein [Function unknown]; Region: COG4695; cl01923
1034836008681	Phage Terminase; Region: Terminase_1; pfam03354
1034836008682	Phage terminase, small subunit; Region: Terminase_4; pfam05119
1034836008683	Prophage antirepressor [Transcription]; Region: COG3617
1034836008684	BRO family, N-terminal domain; Region: Bro-N; smart01040
1034836008685	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1034836008686	non-specific DNA binding site [nucleotide binding]; other site
1034836008687	salt bridge; other site
1034836008688	sequence-specific DNA binding site [nucleotide binding]; other site
1034836008689	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
1034836008690	phiLC3 phage and phage-related integrases, site-specific recombinases, DNA breaking-rejoining enzymes, C-terminal catalytic domain. This CD includes various bacterial (mainly gram positive) and phage integrases, including those similar to Lactococcus...; Region: INT_phiLC3_C; cd01189
1034836008691	Int/Topo IB signature motif; other site
1034836008692	undecaprenyl pyrophosphate phosphatase; Reviewed; Region: PRK00281
1034836008693	Domain of unknown function DUF20; Region: UPF0118; pfam01594
1034836008694	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
1034836008695	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1034836008696	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1034836008697	intracellular protease, PfpI family; Region: PfpI; TIGR01382
1034836008698	A type 1 glutamine amidotransferase (GATase1)-like domain found in PfpI from Pyrococcus furiosus; Region: GATase1_PfpI_like; cd03134
1034836008699	proposed catalytic triad [active]
1034836008700	conserved cys residue [active]
1034836008701	Tar ligand binding domain homologue; Region: TarH; pfam02203
1034836008702	Cache domain; Region: Cache_1; pfam02743
1034836008703	Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840
1034836008704	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1034836008705	dimerization interface [polypeptide binding]; other site
1034836008706	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1034836008707	dimer interface [polypeptide binding]; other site
1034836008708	putative CheW interface [polypeptide binding]; other site
1034836008709	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cl00144
1034836008710	Cache domain; Region: Cache_1; pfam02743
1034836008711	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1034836008712	dimerization interface [polypeptide binding]; other site
1034836008713	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1034836008714	dimer interface [polypeptide binding]; other site
1034836008715	Methyl-accepting chemotaxis protein (MCP) signalling domain; Region: MCPsignal; pfam00015
1034836008716	putative CheW interface [polypeptide binding]; other site
1034836008717	Tar ligand binding domain homologue; Region: TarH; pfam02203
1034836008718	Cache domain; Region: Cache_1; pfam02743
1034836008719	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1034836008720	dimerization interface [polypeptide binding]; other site
1034836008721	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1034836008722	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1034836008723	dimer interface [polypeptide binding]; other site
1034836008724	putative CheW interface [polypeptide binding]; other site
1034836008725	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cl00144
1034836008726	Cache domain; Region: Cache_1; pfam02743
1034836008727	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1034836008728	dimerization interface [polypeptide binding]; other site
1034836008729	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1034836008730	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1034836008731	dimer interface [polypeptide binding]; other site
1034836008732	putative CheW interface [polypeptide binding]; other site
1034836008733	transglutaminase; Provisional; Region: tgl; PRK03187
1034836008734	secondary thiamine-phosphate synthase enzyme; Region: TIGR00149_YjbQ
1034836008735	Nitronate monooxygenase; Region: NMO; pfam03060
1034836008736	2-Nitropropane dioxygenase (NPD), one of the nitroalkane oxidizing enzyme families, catalyzes oxidative denitrification of nitroalkanes to their corresponding carbonyl compounds and nitrites. NDP is a member of the NAD(P)H-dependent flavin oxidoreductase...; Region: NPD_like; cd04730
1034836008737	FMN binding site [chemical binding]; other site
1034836008738	substrate binding site [chemical binding]; other site
1034836008739	putative catalytic residue [active]
1034836008740	alpha,alpha-phosphotrehalase; Region: trehalose_treC; TIGR02403
1034836008741	Alpha amylase catalytic domain found in Sucrose isomerases, oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase), dextran glucosidase (also called glucan 1,6-alpha-glucosidase), and related proteins; Region: AmyAc_SI_OligoGlu_DGase; cd11333
1034836008742	Ca binding site [ion binding]; other site
1034836008743	active site
1034836008744	catalytic site [active]
1034836008745	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
1034836008746	Domain of unknown function DUF21; Region: DUF21; pfam01595
1034836008747	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1034836008748	Transporter associated domain; Region: CorC_HlyC; smart01091
1034836008749	Predicted Zn-dependent protease [General function prediction only]; Region: COG2738
1034836008750	Membrane-integrating protein Mistic; Region: Mistic; pfam11458
1034836008751	Ion channel; Region: Ion_trans_2; pfam07885
1034836008752	Kef-type K+ transport systems, predicted NAD-binding component [Inorganic ion transport and metabolism]; Region: Kch; COG1226
1034836008753	TrkA-N domain; Region: TrkA_N; pfam02254
1034836008754	YugN-like family; Region: YugN; pfam08868
1034836008755	glucose-6-phosphate isomerase; Provisional; Region: pgi; PRK14097
1034836008756	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_1; cd05015
1034836008757	active site
1034836008758	dimer interface [polypeptide binding]; other site
1034836008759	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_2; cd05016
1034836008760	dimer interface [polypeptide binding]; other site
1034836008761	active site
1034836008762	Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family [Energy production and conversion]; Region: COG1979
1034836008763	Butanol dehydrogenase catalyzes the conversion of butyraldehyde to butanol with the cofactor NAD(P)H being oxidized in the process; Region: BDH; cd08187
1034836008764	dimer interface [polypeptide binding]; other site
1034836008765	active site
1034836008766	metal binding site [ion binding]; metal-binding site
1034836008767	Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family [Energy production and conversion]; Region: COG1979
1034836008768	Butanol dehydrogenase catalyzes the conversion of butyraldehyde to butanol with the cofactor NAD(P)H being oxidized in the process; Region: BDH; cd08187
1034836008769	dimer interface [polypeptide binding]; other site
1034836008770	active site
1034836008771	metal binding site [ion binding]; metal-binding site
1034836008772	Uncharacterized conserved protein [Function unknown]; Region: COG2155
1034836008773	general stress protein 13; Validated; Region: PRK08059
1034836008774	S1_RPS1_repeat_hs4: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_hs4; cd05692
1034836008775	RNA binding site [nucleotide binding]; other site
1034836008776	hypothetical protein; Validated; Region: PRK07682
1034836008777	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1034836008778	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1034836008779	homodimer interface [polypeptide binding]; other site
1034836008780	catalytic residue [active]
1034836008781	Transcriptional regulators [Transcription]; Region: Lrp; COG1522
1034836008782	AsnC family; Region: AsnC_trans_reg; pfam01037
1034836008783	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
1034836008784	Domain of unknown function (DUF1871); Region: DUF1871; pfam08958
1034836008785	Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities [Amino acid transport and metabolism]; Region: MalY; COG1168
1034836008786	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1034836008787	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1034836008788	homodimer interface [polypeptide binding]; other site
1034836008789	catalytic residue [active]
1034836008790	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1034836008791	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1034836008792	dimer interface [polypeptide binding]; other site
1034836008793	phosphorylation site [posttranslational modification]
1034836008794	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1034836008795	ATP binding site [chemical binding]; other site
1034836008796	Mg2+ binding site [ion binding]; other site
1034836008797	G-X-G motif; other site
1034836008798	Kinase associated protein B; Region: KapB; pfam08810
1034836008799	DEDDh 3'-5' exonuclease domain of Caenorhabditis elegans ERI-1, human 3' exonuclease, and similar proteins; Region: ERI-1_3'hExo_like; cd06133
1034836008800	active site
1034836008801	catalytic site [active]
1034836008802	substrate binding site [chemical binding]; other site
1034836008803	sugar efflux transporter; Region: 2A0120; TIGR00899
1034836008804	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1034836008805	putative substrate translocation pore; other site
1034836008806	Transglycosylase; Region: Transgly; pfam00912
1034836008807	penicillin-binding protein, 1A family; Region: PBP_1a_fam; TIGR02074
1034836008808	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
1034836008809	Predicted thiol-disulfide oxidoreductase [General function    prediction only]; Region: COG3011
1034836008810	sensory histidine kinase DcuS; Provisional; Region: PRK11086
1034836008811	PAS domain; Region: PAS; smart00091
1034836008812	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1034836008813	ATP binding site [chemical binding]; other site
1034836008814	Mg2+ binding site [ion binding]; other site
1034836008815	G-X-G motif; other site
1034836008816	Response regulator of citrate/malate metabolism [Transcription / Signal transduction mechanisms]; Region: CitB; COG4565
1034836008817	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1034836008818	active site
1034836008819	phosphorylation site [posttranslational modification]
1034836008820	intermolecular recognition site; other site
1034836008821	dimerization interface [polypeptide binding]; other site
1034836008822	Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein [General function prediction only]; Region: Med; COG1744
1034836008823	Periplasmic binding domain of basic membrane lipoprotein, PnrA, in Treponema pallidum and its homologs from other bacteria and Archaea; Region: PBP1_BmpA_PnrA_like; cd06354
1034836008824	ligand binding site [chemical binding]; other site
1034836008825	potential frameshift: common BLAST hit: gi|154687266|ref|YP_001422427.1| YufO
1034836008826	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1034836008827	Transmembrane subunit (TM) of Treponema pallidum (Tp) RbsC-1, RbsC-2 and related proteins. This is a functionally uncharacterized subgroup of TMs which belong to a larger group of TMs of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette; Region: TM_PBP1_transp_TpRbsC_like; cd06580
1034836008828	TM-ABC transporter signature motif; other site
1034836008829	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1034836008830	Transmembrane subunit (TM) of Treponema pallidum (Tp) RbsC-1, RbsC-2 and related proteins. This is a functionally uncharacterized subgroup of TMs which belong to a larger group of TMs of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette; Region: TM_PBP1_transp_TpRbsC_like; cd06580
1034836008831	TM-ABC transporter signature motif; other site
1034836008832	monovalent cation/H+ antiporter subunit A; Reviewed; Region: PRK12645
1034836008833	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1034836008834	Multisubunit Na+/H+ antiporter, MnhB subunit [Inorganic ion transport and metabolism]; Region: MnhB; COG2111
1034836008835	putative monovalent cation/H+ antiporter subunit B; Reviewed; Region: PRK12573
1034836008836	putative monovalent cation/H+ antiporter subunit C; Reviewed; Region: PRK08600
1034836008837	putative monovalent cation/H+ antiporter subunit D; Reviewed; Region: PRK07691
1034836008838	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1034836008839	putative monovalent cation/H+ antiporter subunit E; Reviewed; Region: PRK12651
1034836008840	putative monovalent cation/H+ antiporter subunit F; Reviewed; Region: PRK12600
1034836008841	Na+/H+ antiporter subunit; Region: PhaG_MnhG_YufB; cl00583
1034836008842	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
1034836008843	CoenzymeA binding site [chemical binding]; other site
1034836008844	subunit interaction site [polypeptide binding]; other site
1034836008845	PHB binding site; other site
1034836008846	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1034836008847	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1034836008848	active site
1034836008849	phosphorylation site [posttranslational modification]
1034836008850	intermolecular recognition site; other site
1034836008851	dimerization interface [polypeptide binding]; other site
1034836008852	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1034836008853	DNA binding residues [nucleotide binding]
1034836008854	dimerization interface [polypeptide binding]; other site
1034836008855	potential frameshift: common BLAST hit: gi|154687278|ref|YP_001422439.1| ComP
1034836008856	Bacillus competence pheromone ComX; Region: ComX; pfam05952
1034836008857	Isoprenoid Biosynthesis enzymes, Class 1; Region: Isoprenoid_Biosyn_C1; cl00210
1034836008858	aspartate-rich region 2; other site
1034836008859	DegQ (SacQ) family; Region: DegQ; pfam08181
1034836008860	Predicted signal transduction protein containing EAL and modified HD-GYP domains [Signal transduction mechanisms]; Region: COG3434
1034836008861	EAL domain; Region: EAL; pfam00563
1034836008862	nicotinate phosphoribosyltransferase; Validated; Region: PRK09243
1034836008863	Nicotinate phosphoribosyltransferase (NAPRTase), subgroup A. Nicotinate phosphoribosyltransferase catalyses the formation of NAMN and PPi from 5-phosphoribosy -1-pyrophosphate (PRPP) and nicotinic acid, this is the first, and also rate limiting, reaction...; Region: NAPRTase_A; cd01570
1034836008864	active site
1034836008865	Isochorismatase family; Region: Isochorismatase; pfam00857
1034836008866	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cd00431
1034836008867	catalytic triad [active]
1034836008868	conserved cis-peptide bond; other site
1034836008869	Protein of unknown function (DUF1694); Region: DUF1694; pfam07997
1034836008870	YueH-like protein; Region: YueH; pfam14166
1034836008871	Spore germination protein gerPA/gerPF; Region: gerPA; pfam10676
1034836008872	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
1034836008873	Domain of unknown function DUF20; Region: UPF0118; pfam01594
1034836008874	Protein of unknown function (DUF2642); Region: DUF2642; pfam10842
1034836008875	Predicted HD superfamily hydrolase [General function prediction only]; Region: COG1418
1034836008876	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1034836008877	Zn2+ binding site [ion binding]; other site
1034836008878	Mg2+ binding site [ion binding]; other site
1034836008879	short chain dehydrogenase; Provisional; Region: PRK06924
1034836008880	sepiapterin reductase (SPR)-like, classical (c) SDRs; Region: SPR-like_SDR_c; cd05367
1034836008881	NADP binding site [chemical binding]; other site
1034836008882	homodimer interface [polypeptide binding]; other site
1034836008883	active site
1034836008884	type VII secretion protein EssA; Region: T7SS_EssA_Firm; TIGR03927
1034836008885	type VII secretion protein EsaA, N-terminal domain; Region: T7_esaA_Nterm; TIGR03929
1034836008886	YhgE/Pip N-terminal domain; Region: pip_yhgE_Nterm; TIGR03061
1034836008887	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; cl10482
1034836008888	DNA transporter; Region: FtsK_SpoIIIE_N; pfam12538
1034836008889	type VII secretion protein EssC, C-terminal domain; Region: T7_EssCb_Firm; TIGR03928
1034836008890	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
1034836008891	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
1034836008892	Domain of unknown function DUF87; Region: DUF87; pfam01935
1034836008893	type VII secretion protein EssB; Region: T7_EssB; TIGR03926
1034836008894	WXG100 protein secretion system (Wss), protein YukC; Region: YukC; pfam10140
1034836008895	Uncharacterized small protein [Function unknown]; Region: COG5417
1034836008896	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4842
1034836008897	Regulator of polyketide synthase expression [Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG2508
1034836008898	CodY GAF-like domain; Region: CodY; pfam06018
1034836008899	PucR C-terminal helix-turn-helix domain; Region: HTH_30; pfam13556
1034836008900	Alanine dehydrogenase [Amino acid transport and metabolism]; Region: Ald; COG0686
1034836008901	Alanine dehydrogenase NAD-binding and catalytic domains; Region: L-AlaDH; cd05305
1034836008902	hexamer interface [polypeptide binding]; other site
1034836008903	ligand binding site [chemical binding]; other site
1034836008904	putative active site [active]
1034836008905	NAD(P) binding site [chemical binding]; other site
1034836008906	Uncharacterized conserved protein (DUF2278); Region: DUF2278; pfam10042
1034836008907	MbtH-like protein; Region: MbtH; cl01279
1034836008908	Condensation domain; Region: Condensation; pfam00668
1034836008909	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
1034836008910	amino acid adenylation domain; Region: AA-adenyl-dom; TIGR01733
1034836008911	acyl-activating enzyme (AAE) consensus motif; other site
1034836008912	AMP binding site [chemical binding]; other site
1034836008913	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
1034836008914	enterobactin synthase subunit F; Provisional; Region: entF; PRK10252
1034836008915	HxxPF-repeated domain; Region: HxxPF_rpt; pfam13745
1034836008916	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
1034836008917	acyl-activating enzyme (AAE) consensus motif; other site
1034836008918	AMP binding site [chemical binding]; other site
1034836008919	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
1034836008920	Isochorismatase, also known as 2,3 dihydro-2,3 dihydroxybenzoate synthase, catalyses the conversion of isochorismate, in the presence of water, to 2,3-dihydroxybenzoate and pyruvate, via the hydrolysis of a vinyl ether, an uncommon reaction in biological...; Region: isochorismatase; cd01013
1034836008921	hydrophobic substrate binding pocket; other site
1034836008922	Isochorismatase family; Region: Isochorismatase; pfam00857
1034836008923	active site
1034836008924	conserved cis-peptide bond; other site
1034836008925	Aryl carrier domain [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3433
1034836008926	Peptide arylation enzymes [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntE; COG1021
1034836008927	2,3-dihydroxybenzoate-AMP ligase; Region: 23DHB-AMP_lg; cd05920
1034836008928	acyl-activating enzyme (AAE) consensus motif; other site
1034836008929	active site
1034836008930	AMP binding site [chemical binding]; other site
1034836008931	substrate binding site [chemical binding]; other site
1034836008932	isochorismate synthase DhbC; Validated; Region: PRK06923
1034836008933	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
1034836008934	2,3-dihydroxybenzoate-2,3-dehydrogenase; Validated; Region: PRK08220
1034836008935	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1034836008936	NAD(P) binding site [chemical binding]; other site
1034836008937	active site
1034836008938	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
1034836008939	Sulfite oxidase and related enzymes [General function prediction only]; Region: COG2041
1034836008940	bacterial and archael members of the sulfite oxidase (SO) family of molybdopterin binding domains. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and...; Region: arch_bact_SO_family_Moco; cd02109
1034836008941	Moco binding site; other site
1034836008942	metal coordination site [ion binding]; other site
1034836008943	Uncharacterized conserved protein [General function prediction only]; Region: BioY; COG1268
1034836008944	Predicted permease [General function prediction only]; Region: COG2056
1034836008945	Na+-H+ antiporter family; Region: Na_H_antiport_2; pfam13726
1034836008946	multifunctional aminopeptidase A; Provisional; Region: PRK00913
1034836008947	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
1034836008948	interface (dimer of trimers) [polypeptide binding]; other site
1034836008949	Substrate-binding/catalytic site; other site
1034836008950	Zn-binding sites [ion binding]; other site
1034836008951	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1963
1034836008952	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3584
1034836008953	Putative membrane protein; Region: YuiB; pfam14068
1034836008954	Archaea-specific RecJ-like exonuclease, contains DnaJ-type Zn finger domain [DNA replication, recombination, and repair]; Region: COG1107
1034836008955	NADH dehydrogenase, FAD-containing subunit [Energy production and conversion]; Region: Ndh; COG1252
1034836008956	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1034836008957	Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones]; Region: TrxB; COG0492
1034836008958	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1034836008959	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1034836008960	guanosine 5'-monophosphate oxidoreductase; Provisional; Region: PRK05458
1034836008961	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
1034836008962	active site
1034836008963	Integral membrane protein DUF95; Region: DUF95; pfam01944
1034836008964	ABC-type Na+ transport system, ATPase component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatA; COG4555
1034836008965	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1034836008966	Walker A/P-loop; other site
1034836008967	ATP binding site [chemical binding]; other site
1034836008968	Q-loop/lid; other site
1034836008969	ABC transporter signature motif; other site
1034836008970	Walker B; other site
1034836008971	D-loop; other site
1034836008972	H-loop/switch region; other site
1034836008973	potential frameshift: common BLAST hit: gi|154687326|ref|YP_001422487.1| YjcK
1034836008974	Short-chain dehydrogenase involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein) [Cell envelope biogenesis, outer membrane]; Region: DltE; COG3967
1034836008975	classical (c) SDR, subgroup 2; Region: SDR_c2; cd05370
1034836008976	putative NAD(P) binding site [chemical binding]; other site
1034836008977	active site
1034836008978	Phage holin; Region: Phage_holin_5; pfam06946
1034836008979	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
1034836008980	amidase catalytic site [active]
1034836008981	Zn binding residues [ion binding]; other site
1034836008982	substrate binding site [chemical binding]; other site
1034836008983	FOG: LysM repeat [Cell envelope biogenesis, outer membrane]; Region: LytE; COG1388
1034836008984	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1034836008985	Phage uncharacterized protein (Phage_XkdX); Region: Phage_XkdX; pfam09693
1034836008986	Domain of unknown function (DUF2479); Region: DUF2479; pfam10651
1034836008987	Pectate lyase superfamily protein; Region: Pectate_lyase_3; pfam12708
1034836008988	Peptidase_G2, IMC autoproteolytic cleavage domain; Region: Peptidase_G2; pfam11962
1034836008989	Prophage endopeptidase tail; Region: Prophage_tail; pfam06605
1034836008990	Muramidase (flagellum-specific) [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FlgJ; COG1705
1034836008991	Phage tail protein; Region: Sipho_tail; pfam05709
1034836008992	phage tail tape measure protein, TP901 family, core region; Region: tape_meas_TP901; TIGR01760
1034836008993	Phosphoinositide-specific phospholipase C, efhand-like; Region: efhand_like; pfam09279
1034836008994	phage tail tape measure protein, TP901 family, core region; Region: tape_meas_TP901; TIGR01760
1034836008995	Phage minor capsid protein 2; Region: Phage_min_cap2; pfam06152
1034836008996	Phage portal protein, SPP1 Gp6-like; Region: Phage_prot_Gp6; pfam05133
1034836008997	Helix-turn-helix of insertion element transposase; Region: HTH_Tnp_1_2; pfam13022
1034836008998	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5410
1034836008999	Phage-related terminase [General function prediction only]; Region: COG5362; cl02216
1034836009000	INT_SG3, DNA breaking-rejoining enzymes, integrase/recombinases subgroup 3, catalytic domain. The CD contains various predicted bacterial and phage integrase/recombinase sequences for which not much experimental characterization is available; Region: INT_SG3_C; cd01186
1034836009001	Int/Topo IB signature motif; other site
1034836009002	Mn-dependent transcriptional regulator [Transcription]; Region: TroR; COG1321
1034836009003	Cro/C1-type HTH DNA-binding domain; Region: HTH_26; pfam13443
1034836009004	Helix-turn-helix domain; Region: HTH_36; pfam13730
1034836009005	Site-specific recombinase XerD [DNA replication, recombination, and repair]; Region: XerD; COG4974
1034836009006	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1034836009007	active site
1034836009008	DNA binding site [nucleotide binding]
1034836009009	Int/Topo IB signature motif; other site
1034836009010	Fe-S cluster assembly scaffold protein [Posttranslational modification, protein turnover, chaperones]; Region: sufA; COG0316
1034836009011	diaminopimelate epimerase; Provisional; Region: dapF; PRK00450
1034836009012	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
1034836009013	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
1034836009014	Nucleoside permease [Nucleotide transport and metabolism]; Region: NupC; COG1972
1034836009015	Na+ dependent nucleoside transporter N-terminus; Region: Nucleos_tra2_N; pfam01773
1034836009016	Nucleoside recognition; Region: Gate; pfam07670
1034836009017	Na+ dependent nucleoside transporter C-terminus; Region: Nucleos_tra2_C; pfam07662
1034836009018	hypothetical protein; Provisional; Region: PRK13669
1034836009019	NADH dehydrogenase, FAD-containing subunit [Energy production and conversion]; Region: Ndh; COG1252
1034836009020	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1034836009021	Protein of unknown function (DUF1462); Region: DUF1462; pfam07315
1034836009022	NifU-like domain; Region: NifU; pfam01106
1034836009023	Dipeptidyl aminopeptidases/acylaminoacyl-peptidases [Amino acid transport and metabolism]; Region: DAP2; COG1506
1034836009024	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
1034836009025	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cl02567
1034836009026	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1034836009027	homoserine kinase; Region: thrB; TIGR00191
1034836009028	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
1034836009029	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
1034836009030	threonine synthase; Reviewed; Region: PRK06721
1034836009031	Threonine synthase is a pyridoxal phosphate (PLP) dependent enzyme that catalyses the last reaction in the synthesis of  threonine from aspartate. It proceeds by converting O-phospho-L-homoserine (OPH) into threonine and inorganic phosphate. In plants; Region: Thr-synth_1; cd01563
1034836009032	homodimer interface [polypeptide binding]; other site
1034836009033	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1034836009034	catalytic residue [active]
1034836009035	homoserine dehydrogenase; Provisional; Region: PRK06349
1034836009036	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
1034836009037	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
1034836009038	ACT_HSDH_Hom CD includes the C-terminal ACT domain of the NAD(P)H-dependent, homoserine dehydrogenase (HSDH) and related domains; Region: ACT_HSDH-Hom; cd04881
1034836009039	spore coat protein YutH; Region: spore_yutH; TIGR02905
1034836009040	Phosphatidylglycerophosphatase A; a bacterial membrane-associated enzyme involved in lipid metabolism; Region: PgpA; cd06971
1034836009041	tetramer interfaces [polypeptide binding]; other site
1034836009042	binuclear metal-binding site [ion binding]; other site
1034836009043	HAD-superfamily subfamily IIA hydrolase, TIGR01457; Region: HAD-SF-IIA-hyp2
1034836009044	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1034836009045	active site
1034836009046	motif I; other site
1034836009047	motif II; other site
1034836009048	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1034836009049	Uncharacterized conserved protein [Function unknown]; Region: COG2445
1034836009050	Protein of unknown function (DUF1027); Region: DUF1027; pfam06265
1034836009051	lipoyl synthase; Provisional; Region: PRK05481
1034836009052	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1034836009053	FeS/SAM binding site; other site
1034836009054	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
1034836009055	Peptidase family M23; Region: Peptidase_M23; pfam01551
1034836009056	sporulation protein YunB; Region: spo_yunB; TIGR02832
1034836009057	5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases [Nucleotide transport and metabolism]; Region: UshA; COG0737
1034836009058	Escherichia coli UshA-like family, N-terminal metallophosphatase domain; Region: MPP_UshA_N_like; cd00845
1034836009059	active site
1034836009060	metal binding site [ion binding]; metal-binding site
1034836009061	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
1034836009062	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
1034836009063	Uncharacterized conserved protein [Function unknown]; Region: COG1801
1034836009064	allantoinase; Provisional; Region: PRK06189
1034836009065	L-Hydantoinases (L-HYDs) and Allantoinase (ALN); L-Hydantoinases are a member of the dihydropyrimidinase family, which catalyzes the reversible hydrolytic ring opening of dihydropyrimidines and hydantoins (five-membered cyclic diamides used in...; Region: L-HYD_ALN; cd01315
1034836009066	active site
1034836009067	Purine catabolism regulatory protein-like family; Region: PucR; pfam07905
1034836009068	Regulator of polyketide synthase expression [Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG2508
1034836009069	PucR C-terminal helix-turn-helix domain; Region: HTH_30; pfam13556
1034836009070	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1034836009071	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1034836009072	putative substrate translocation pore; other site
1034836009073	Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase [Amino acid transport and metabolism]; Region: COG0075
1034836009074	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1034836009075	catalytic residue [active]
1034836009076	allantoate amidohydrolase; Reviewed; Region: PRK09290
1034836009077	M20 Peptidase beta-alanine synthase, an amidohydrolase; Region: M20_bAS; cd03884
1034836009078	active site
1034836009079	metal binding site [ion binding]; metal-binding site
1034836009080	dimer interface [polypeptide binding]; other site
1034836009081	Endonuclease I; Region: Endonuclease_1; pfam04231
1034836009082	glycerol-3-phosphate transporter ATP-binding subunit; Provisional; Region: ugpC; PRK11650
1034836009083	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
1034836009084	Walker A/P-loop; other site
1034836009085	ATP binding site [chemical binding]; other site
1034836009086	Q-loop/lid; other site
1034836009087	ABC transporter signature motif; other site
1034836009088	Walker B; other site
1034836009089	D-loop; other site
1034836009090	H-loop/switch region; other site
1034836009091	TOBE domain; Region: TOBE_2; pfam08402
1034836009092	DNA-binding transcriptional regulator FrlR; Provisional; Region: PRK11402
1034836009093	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1034836009094	DNA-binding site [nucleotide binding]; DNA binding site
1034836009095	UTRA domain; Region: UTRA; pfam07702
1034836009096	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1034836009097	ribokinase/pfkB superfamily: Kinases that accept a wide variety of substrates, including carbohydrates and aromatic small molecules, all are phosphorylated at a hydroxyl group. The superfamily includes ribokinase, fructokinase, ketohexokinase; Region: ribokinase_pfkB_like; cl00192
1034836009098	substrate binding site [chemical binding]; other site
1034836009099	ATP binding site [chemical binding]; other site
1034836009100	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1034836009101	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1034836009102	dimer interface [polypeptide binding]; other site
1034836009103	conserved gate region; other site
1034836009104	putative PBP binding loops; other site
1034836009105	ABC-ATPase subunit interface; other site
1034836009106	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1034836009107	dimer interface [polypeptide binding]; other site
1034836009108	conserved gate region; other site
1034836009109	putative PBP binding loops; other site
1034836009110	ABC-ATPase subunit interface; other site
1034836009111	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
1034836009112	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
1034836009113	Predicted phosphosugar isomerases [Cell envelope biogenesis, outer membrane]; Region: AgaS; COG2222
1034836009114	A subgroup of the SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars; Region: SIS_1; cd05710
1034836009115	putative active site [active]
1034836009116	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
1034836009117	dimer interface [polypeptide binding]; other site
1034836009118	active site
1034836009119	Predicted transcriptional regulators [Transcription]; Region: SoxR; COG0789
1034836009120	Helix-Turn-Helix DNA binding domain of MerR-like transcription regulators; Region: HTH_MerR-like; cd00592
1034836009121	DNA binding residues [nucleotide binding]
1034836009122	dimer interface [polypeptide binding]; other site
1034836009123	antimicrobial peptide, SdpC family; Region: toxin_SdpC; TIGR04032
1034836009124	Vitamin K-dependent gamma-carboxylase; Region: VKG_Carbox; cl02773
1034836009125	antimicrobial peptide system protein, SdpA family; Region: export_SdpA; TIGR04034
1034836009126	Protein of unknown function (DUF1648); Region: DUF1648; pfam07853
1034836009127	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
1034836009128	GIY-YIG motif/motif A; other site
1034836009129	active site
1034836009130	catalytic site [active]
1034836009131	putative DNA binding site [nucleotide binding]; other site
1034836009132	metal binding site [ion binding]; metal-binding site
1034836009133	Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665
1034836009134	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1034836009135	S-adenosylmethionine binding site [chemical binding]; other site
1034836009136	Protein of unknown function (DUF2691); Region: DUF2691; pfam10903
1034836009137	Glycosyl hydrolase family 46 chitosanase domain. This family are composed of the chitosanase enzymes which hydrolyzes chitosan, a biopolymer of beta (1,4)-linked -D-glucosamine (GlcN) residues produced by partial or full deacetylation of chitin; Region: chitosanase_glyco_hydro_46; cd00978
1034836009138	chitosan binding site [chemical binding]; other site
1034836009139	catalytic residues [active]
1034836009140	cysteine desulfurase activator complex subunit SufB; Provisional; Region: PRK11814; cl03223
1034836009141	FeS assembly protein SufB; Region: sufB; TIGR01980
1034836009142	NifU homolog involved in Fe-S cluster formation [Energy production and conversion]; Region: IscU; COG0822
1034836009143	Iron-sulfur cluster scaffold-like proteins; Region: IscU_like; cd06664
1034836009144	trimerization site [polypeptide binding]; other site
1034836009145	active site
1034836009146	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
1034836009147	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
1034836009148	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1034836009149	catalytic residue [active]
1034836009150	Cysteine desulfurase activator SufB [Posttranslational modification, protein turnover, chaperones]; Region: SufB; COG0719
1034836009151	FeS assembly protein SufD; Region: sufD; TIGR01981
1034836009152	Cysteine desulfurase activator ATPase [Posttranslational modification, protein turnover, chaperones]; Region: sufC; COG0396
1034836009153	ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Region: ABC_FeS_Assembly; cd03217
1034836009154	Walker A/P-loop; other site
1034836009155	ATP binding site [chemical binding]; other site
1034836009156	Q-loop/lid; other site
1034836009157	ABC transporter signature motif; other site
1034836009158	Walker B; other site
1034836009159	D-loop; other site
1034836009160	H-loop/switch region; other site
1034836009161	Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit [Function unknown]; Region: COG0599
1034836009162	ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism]; Region: NlpA; COG1464
1034836009163	NLPA lipoprotein; Region: Lipoprotein_9; pfam03180
1034836009164	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1034836009165	dimer interface [polypeptide binding]; other site
1034836009166	conserved gate region; other site
1034836009167	ABC-ATPase subunit interface; other site
1034836009168	ABC-type metal ion transport system, ATPase component [Inorganic ion transport and metabolism]; Region: AbcC; COG1135
1034836009169	ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258
1034836009170	Walker A/P-loop; other site
1034836009171	ATP binding site [chemical binding]; other site
1034836009172	Q-loop/lid; other site
1034836009173	ABC transporter signature motif; other site
1034836009174	Walker B; other site
1034836009175	D-loop; other site
1034836009176	H-loop/switch region; other site
1034836009177	NIL domain; Region: NIL; pfam09383
1034836009178	SCP-2 sterol transfer family; Region: SCP2; pfam02036
1034836009179	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
1034836009180	catalytic residues [active]
1034836009181	TOPRIM_ RNase M5_like: The topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain found in Ribonuclease M5: (RNase M5) and other small primase-like proteins from bacteria and archaea.  RNase M5 catalyzes the maturation of 5S rRNA in low...; Region: TOPRIM_RNase_M5_like; cd01027
1034836009182	putative active site [active]
1034836009183	putative metal binding site [ion binding]; other site
1034836009184	Protein of unknown function (DUF2553); Region: DUF2553; pfam10830
1034836009185	Glycine cleavage H-protein. Glycine cleavage H-proteins are part of the glycine cleavage system (GCS) found in bacteria, archea and the mitochondria of eukaryotes. GCS is a multienzyme complex consisting of 4 different components (P-, H-, T- and...; Region: GCS_H; cd06848
1034836009186	lipoyl attachment site [posttranslational modification]; other site
1034836009187	Arsenate Reductase (ArsC) family, unknown subfamily; uncharacterized proteins containing a CXXC motif with similarity to thioredoxin (TRX)-fold arsenic reductases, ArsC. Proteins containing a redox active CXXC motif like TRX and glutaredoxin (GRX)...; Region: ArsC_like; cd03036
1034836009188	ArsC family; Region: ArsC; pfam03960
1034836009189	putative ArsC-like catalytic residues; other site
1034836009190	putative TRX-like catalytic residues [active]
1034836009191	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
1034836009192	Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960
1034836009193	active site
1034836009194	acetyl-CoA acetyltransferase; Provisional; Region: PRK07661
1034836009195	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
1034836009196	dimer interface [polypeptide binding]; other site
1034836009197	active site
1034836009198	3-hydroxyacyl-CoA dehydrogenase [Lipid metabolism]; Region: FadB; COG1250
1034836009199	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
1034836009200	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
1034836009201	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
1034836009202	Enoyl-CoA hydratase/carnithine racemase [Lipid metabolism]; Region: CaiD; COG1024
1034836009203	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
1034836009204	substrate binding site [chemical binding]; other site
1034836009205	oxyanion hole (OAH) forming residues; other site
1034836009206	trimer interface [polypeptide binding]; other site
1034836009207	YuzL-like protein; Region: YuzL; pfam14115
1034836009208	Proline dehydrogenase; Region: Pro_dh; cl03282
1034836009209	Pyruvate formate lyase; Region: PFL; pfam02901
1034836009210	Coat F domain; Region: Coat_F; pfam07875
1034836009211	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1034836009212	MarR family; Region: MarR; pfam01047
1034836009213	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1034836009214	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1034836009215	putative substrate translocation pore; other site
1034836009216	Restriction endonuclease BamHI; Region: BamHI; pfam02923
1034836009217	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1034836009218	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1034836009219	non-specific DNA binding site [nucleotide binding]; other site
1034836009220	salt bridge; other site
1034836009221	sequence-specific DNA binding site [nucleotide binding]; other site
1034836009222	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1034836009223	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
1034836009224	DNA methylase; Region: N6_N4_Mtase; pfam01555
1034836009225	Protein of unknown function (DUF2573); Region: DUF2573; pfam10835
1034836009226	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
1034836009227	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
1034836009228	Walker A/P-loop; other site
1034836009229	ATP binding site [chemical binding]; other site
1034836009230	Q-loop/lid; other site
1034836009231	ABC transporter signature motif; other site
1034836009232	Walker B; other site
1034836009233	D-loop; other site
1034836009234	H-loop/switch region; other site
1034836009235	YusW-like protein; Region: YusW; pfam14039
1034836009236	oligoendopeptidase, pepF/M3 family; Region: M3_fam_3; TIGR02290
1034836009237	Peptidase family M3B Oligopeptidase F (PepF); Region: M3B_PepF_2; cd09607
1034836009238	active site
1034836009239	Zn binding site [ion binding]; other site
1034836009240	short chain dehydrogenase; Provisional; Region: PRK06914
1034836009241	17beta hydroxysteroid dehydrogenase-like, classical (c) SDRs; Region: 17beta-HSD-like_SDR_c; cd05374
1034836009242	NADP binding site [chemical binding]; other site
1034836009243	active site
1034836009244	steroid binding site; other site
1034836009245	DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism]; Region: Dps; COG0783
1034836009246	DPS protein, ferritin-like diiron-binding domain; Region: DPS; cd01043
1034836009247	dimerization interface [polypeptide binding]; other site
1034836009248	DPS ferroxidase diiron center [ion binding]; other site
1034836009249	ion pore; other site
1034836009250	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
1034836009251	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1034836009252	protein binding site [polypeptide binding]; other site
1034836009253	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1034836009254	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1034836009255	active site
1034836009256	phosphorylation site [posttranslational modification]
1034836009257	intermolecular recognition site; other site
1034836009258	dimerization interface [polypeptide binding]; other site
1034836009259	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1034836009260	DNA binding site [nucleotide binding]
1034836009261	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1034836009262	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1034836009263	dimerization interface [polypeptide binding]; other site
1034836009264	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1034836009265	dimer interface [polypeptide binding]; other site
1034836009266	phosphorylation site [posttranslational modification]
1034836009267	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1034836009268	ATP binding site [chemical binding]; other site
1034836009269	Mg2+ binding site [ion binding]; other site
1034836009270	G-X-G motif; other site
1034836009271	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1034836009272	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1034836009273	fumarate hydratase; Reviewed; Region: fumC; PRK00485
1034836009274	Class II fumarases; Region: Fumarase_classII; cd01362
1034836009275	active site
1034836009276	tetramer interface [polypeptide binding]; other site
1034836009277	Protein of unknown function (DUF3970); Region: DUF3970; pfam13113
1034836009278	Bacillus/Clostridium GerA spore germination protein; Region: GerA; pfam03323
1034836009279	Spore germination protein; Region: Spore_permease; pfam03845
1034836009280	germination protein, Ger(x)C family; Region: spore_ger_x_C; TIGR02887
1034836009281	Spore germination B3/ GerAC like, C-terminal; Region: Spore_GerAC; pfam05504
1034836009282	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1034836009283	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1034836009284	active site
1034836009285	phosphorylation site [posttranslational modification]
1034836009286	intermolecular recognition site; other site
1034836009287	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1034836009288	DNA binding residues [nucleotide binding]
1034836009289	dimerization interface [polypeptide binding]; other site
1034836009290	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG4585
1034836009291	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1034836009292	dimerization interface [polypeptide binding]; other site
1034836009293	Histidine kinase; Region: HisKA_3; pfam07730
1034836009294	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1034836009295	ATP binding site [chemical binding]; other site
1034836009296	Mg2+ binding site [ion binding]; other site
1034836009297	G-X-G motif; other site
1034836009298	Predicted membrane protein [Function unknown]; Region: COG4758
1034836009299	Cell wall-active antibiotics response protein (DUF2154); Region: DUF2154; pfam09922
1034836009300	Domain of unknown function (DUF4097); Region: DUF4097; pfam13349
1034836009301	Domain of unknown function (DUF4098); Region: DUF4098; pfam13345
1034836009302	PspA/IM30 family; Region: PspA_IM30; pfam04012
1034836009303	putative uroporphyrinogen III C-methyltransferase; Provisional; Region: PRK10920
1034836009304	Flagellar biosynthesis pathway, component FlhA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FlhA; cl07980
1034836009305	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1034836009306	H+ Antiporter protein; Region: 2A0121; TIGR00900
1034836009307	putative substrate translocation pore; other site
1034836009308	cob(I)alamin adenosyltransferase [Coenzyme transport and    metabolism]; Region: COG2096
1034836009309	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
1034836009310	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
1034836009311	Walker A/P-loop; other site
1034836009312	ATP binding site [chemical binding]; other site
1034836009313	Q-loop/lid; other site
1034836009314	ABC transporter signature motif; other site
1034836009315	Walker B; other site
1034836009316	D-loop; other site
1034836009317	H-loop/switch region; other site
1034836009318	Adenosylcobinamide amidohydrolase; Region: CbiZ; cl00808
1034836009319	ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism]; Region: FepG; COG4779
1034836009320	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1034836009321	ABC-ATPase subunit  interface; other site
1034836009322	dimer interface [polypeptide binding]; other site
1034836009323	putative PBP binding regions; other site
1034836009324	ABC-type Fe3+-hydroxamate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: FepB; COG0614
1034836009325	Periplasmic binding protein YvrC.  These proteins are predicted to function as initial receptors in ABC transport of metal ions in eubacteria and archaea.  They belong to the TroA superfamily of periplasmic metal binding proteins that share a distinct...; Region: YvrC; cd01143
1034836009326	putative binding site residues; other site
1034836009327	3-ketoacyl-(acyl-carrier-protein) reductase; Provisional; Region: fabG; PRK07231
1034836009328	classical (c) SDRs; Region: SDR_c; cd05233
1034836009329	NAD(P) binding site [chemical binding]; other site
1034836009330	active site
1034836009331	SMP-30/Gluconolaconase/LRE-like region; Region: SGL; pfam08450
1034836009332	Predicted signal transduction protein with a C-terminal ATPase domain [Signal transduction mechanisms]; Region: COG2972
1034836009333	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1034836009334	dimer interface [polypeptide binding]; other site
1034836009335	phosphorylation site [posttranslational modification]
1034836009336	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1034836009337	ATP binding site [chemical binding]; other site
1034836009338	Mg2+ binding site [ion binding]; other site
1034836009339	G-X-G motif; other site
1034836009340	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1034836009341	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1034836009342	active site
1034836009343	phosphorylation site [posttranslational modification]
1034836009344	intermolecular recognition site; other site
1034836009345	dimerization interface [polypeptide binding]; other site
1034836009346	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1034836009347	DNA binding site [nucleotide binding]
1034836009348	hypothetical protein; Provisional; Region: PRK14082
1034836009349	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
1034836009350	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1034836009351	DNA binding residues [nucleotide binding]
1034836009352	YvrJ protein family; Region: YvrJ; pfam12841
1034836009353	bicupin, oxalate decarboxylase family; Region: bicupin_oxalic; TIGR03404
1034836009354	Cupin; Region: Cupin_1; smart00835
1034836009355	Cupin; Region: Cupin_1; smart00835
1034836009356	Regulatory protein YrvL; Region: YrvL; pfam14184
1034836009357	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
1034836009358	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
1034836009359	Walker A/P-loop; other site
1034836009360	ATP binding site [chemical binding]; other site
1034836009361	Q-loop/lid; other site
1034836009362	ABC transporter signature motif; other site
1034836009363	Walker B; other site
1034836009364	D-loop; other site
1034836009365	H-loop/switch region; other site
1034836009366	ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism]; Region: FepG; COG4779
1034836009367	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1034836009368	ABC-ATPase subunit  interface; other site
1034836009369	dimer interface [polypeptide binding]; other site
1034836009370	putative PBP binding regions; other site
1034836009371	ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism]; Region: FepG; COG4779
1034836009372	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1034836009373	ABC-ATPase subunit  interface; other site
1034836009374	dimer interface [polypeptide binding]; other site
1034836009375	putative PBP binding regions; other site
1034836009376	ABC-type Fe3+-hydroxamate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: FepB; COG0614
1034836009377	Periplasmic binding protein FeuA.  These proteins have predicted to function as initial receptors in ABC transport of metal ions in some eubacterial species.  They belong to the TroA superfamily of periplasmic metal binding proteins that share a distinct...; Region: FeuA; cd01138
1034836009378	putative ligand binding residues [chemical binding]; other site
1034836009379	O-Methyltransferase involved in polyketide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3315
1034836009380	Leucine carboxyl methyltransferase; Region: LCM; pfam04072
1034836009381	histidine-histamine antiporter; Region: his_histam_anti; TIGR04298
1034836009382	Predicted membrane-bound metal-dependent hydrolase (DUF457); Region: DUF457; pfam04307
1034836009383	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily [Cell envelope biogenesis, outer membrane]; Region: MdoB; COG1368
1034836009384	Sulfatase; Region: Sulfatase; pfam00884
1034836009385	DNA binding domain, excisionase family; Region: excise; TIGR01764
1034836009386	Periplasmic molybdate-binding protein/domain [Inorganic ion transport and metabolism]; Region: COG1910
1034836009387	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
1034836009388	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
1034836009389	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
1034836009390	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1034836009391	dimer interface [polypeptide binding]; other site
1034836009392	conserved gate region; other site
1034836009393	putative PBP binding loops; other site
1034836009394	ABC-ATPase subunit interface; other site
1034836009395	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1034836009396	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1034836009397	active site
1034836009398	phosphorylation site [posttranslational modification]
1034836009399	intermolecular recognition site; other site
1034836009400	dimerization interface [polypeptide binding]; other site
1034836009401	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1034836009402	DNA binding residues [nucleotide binding]
1034836009403	dimerization interface [polypeptide binding]; other site
1034836009404	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG4585
1034836009405	Histidine kinase; Region: HisKA_3; pfam07730
1034836009406	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Region: HATPase_c; pfam02518
1034836009407	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
1034836009408	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1034836009409	Walker A/P-loop; other site
1034836009410	ATP binding site [chemical binding]; other site
1034836009411	Q-loop/lid; other site
1034836009412	ABC transporter signature motif; other site
1034836009413	Walker B; other site
1034836009414	D-loop; other site
1034836009415	H-loop/switch region; other site
1034836009416	ABC-type Na+ efflux pump, permease component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatB; COG1668
1034836009417	ABC-2 family transporter protein; Region: ABC2_membrane_2; cl17866
1034836009418	ABC-type Na+ efflux pump, permease component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatB; COG1668
1034836009419	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
1034836009420	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
1034836009421	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1034836009422	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1034836009423	active site
1034836009424	catalytic tetrad [active]
1034836009425	NhaP-type Na+/H+ and K+/H+ antiporters [Inorganic ion transport and metabolism]; Region: NhaP; COG0025
1034836009426	sulfite reductase subunit beta; Provisional; Region: PRK13504
1034836009427	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
1034836009428	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
1034836009429	sulfite reductase [NADPH] flavoprotein, alpha-component; Region: cysJ; TIGR01931
1034836009430	Flavodoxin; Region: Flavodoxin_1; pfam00258
1034836009431	Cytochrome p450- like alpha subunits of E. coli sulfite reductase (SiR) multimerize with beta subunits to catalyze the NADPH dependent reduction of sulfite to sulfide. Beta subunits have an Fe4S4 cluster and a siroheme, while the alpha subunits (cysJ...; Region: SiR; cd06199
1034836009432	FAD binding pocket [chemical binding]; other site
1034836009433	FAD binding motif [chemical binding]; other site
1034836009434	catalytic residues [active]
1034836009435	NAD binding pocket [chemical binding]; other site
1034836009436	phosphate binding motif [ion binding]; other site
1034836009437	beta-alpha-beta structure motif; other site
1034836009438	Superfamily I DNA and RNA helicases [General function prediction only]; Region: COG3973
1034836009439	Family description; Region: UvrD_C_2; pfam13538
1034836009440	Predicted membrane protein [Function unknown]; Region: COG2860
1034836009441	UPF0126 domain; Region: UPF0126; pfam03458
1034836009442	UPF0126 domain; Region: UPF0126; pfam03458
1034836009443	Metallo-peptidase family M84; Region: Peptidase_M84; pfam13688
1034836009444	active site
1034836009445	Disulfide bond formation protein DsbB; Region: DsbB; cl00649
1034836009446	Protein-disulfide isomerase [Posttranslational modification, protein turnover, chaperones]; Region: DsbG; COG1651
1034836009447	Thioredoxin; Region: Thioredoxin_4; pfam13462
1034836009448	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217
1034836009449	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
1034836009450	metal-binding site [ion binding]
1034836009451	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1034836009452	Soluble P-type ATPase [General function prediction only]; Region: COG4087
1034836009453	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217
1034836009454	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
1034836009455	metal-binding site [ion binding]
1034836009456	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217
1034836009457	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
1034836009458	metal-binding site [ion binding]
1034836009459	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1034836009460	Soluble P-type ATPase [General function prediction only]; Region: COG4087
1034836009461	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217
1034836009462	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
1034836009463	metal-binding site [ion binding]
1034836009464	Transcriptional regulators CsoR (copper-sensitive operon repressor), RcnR, and FrmR, and related domains; this domain superfamily was previously known as DUF156; Region: CsoR-like_DUF156; cl00846
1034836009465	putative homodimer interface [polypeptide binding]; other site
1034836009466	putative homotetramer interface [polypeptide binding]; other site
1034836009467	putative allosteric switch controlling residues; other site
1034836009468	putative metal binding site [ion binding]; other site
1034836009469	putative homodimer-homodimer interface [polypeptide binding]; other site
1034836009470	putative oxidoreductase; Provisional; Region: PRK11579
1034836009471	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1034836009472	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1034836009473	azoreductase; Reviewed; Region: PRK00170
1034836009474	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
1034836009475	nitrilotriacetate monoxygenase oxidizes nitrilotriacetate utilizing reduced flavin mononucleotide (FMNH2) and oxygen. The FMNH2 is provided by an NADH:flavin mononucleotide (FMN) oxidorductase that uses NADH to reduce FMN to FMNH2; Region: Nitrilotriacetate_monoxgenase; cd01095
1034836009476	FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family; Region: FMN_nitrolo; TIGR03860
1034836009477	active site
1034836009478	non-prolyl cis peptide bond; other site
1034836009479	NrdH-redoxin (NrdH) family; NrdH is a small monomeric protein with a conserved redox active CXXC motif within a TRX fold, characterized by a glutaredoxin (GRX)-like sequence and TRX-like activity profile. In vitro, it displays protein disulfide reductase...; Region: NrdH; cd02976
1034836009480	catalytic residues [active]
1034836009481	luciferase family oxidoreductase, group 1; Region: oxido_grp_1; TIGR03558
1034836009482	probable oxidoreductase, LLM family; Region: LLM_2I7G; TIGR03858
1034836009483	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
1034836009484	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1034836009485	Walker A/P-loop; other site
1034836009486	ATP binding site [chemical binding]; other site
1034836009487	Q-loop/lid; other site
1034836009488	ABC transporter signature motif; other site
1034836009489	Walker B; other site
1034836009490	D-loop; other site
1034836009491	H-loop/switch region; other site
1034836009492	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1034836009493	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1034836009494	dimer interface [polypeptide binding]; other site
1034836009495	conserved gate region; other site
1034836009496	putative PBP binding loops; other site
1034836009497	ABC-ATPase subunit interface; other site
1034836009498	amine acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family; Region: HEQRo_perm_3TM; TIGR01726
1034836009499	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1034836009500	dimer interface [polypeptide binding]; other site
1034836009501	conserved gate region; other site
1034836009502	putative PBP binding loops; other site
1034836009503	ABC-ATPase subunit interface; other site
1034836009504	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
1034836009505	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1034836009506	substrate binding pocket [chemical binding]; other site
1034836009507	membrane-bound complex binding site; other site
1034836009508	hinge residues; other site
1034836009509	Bacterial periplasmic substrate-binding proteins; Region: PBPb; smart00062
1034836009510	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1034836009511	substrate binding pocket [chemical binding]; other site
1034836009512	membrane-bound complex binding site; other site
1034836009513	hinge residues; other site
1034836009514	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
1034836009515	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1034836009516	Coenzyme A binding pocket [chemical binding]; other site
1034836009517	GNAT acetyltransferase 2; Region: GNAT_acetyltr_2; pfam13718
1034836009518	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1034836009519	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1034836009520	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1034836009521	dimerization interface [polypeptide binding]; other site
1034836009522	potential frameshift: common BLAST hit: gi|375363802|ref|YP_005131841.1| 3-oxoacyl-ACP reductase
1034836009523	short chain dehydrogenase; Provisional; Region: PRK06523
1034836009524	classical (c) SDRs; Region: SDR_c; cd05233
1034836009525	NAD(P) binding site [chemical binding]; other site
1034836009526	active site
1034836009527	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1034836009528	Barstar is an intracellular inhibitor of barnase, an extracellular ribonuclease of Bacillus amyloliquefaciens. Barstar binds tightly to the barnase active site and sterically blocks it thus inhibiting its potentially lethal RNase activity inside the cell; Region: Barstar; cd05142
1034836009529	RNAase interaction site [polypeptide binding]; other site
1034836009530	Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294
1034836009531	SmpB-tmRNA interface; other site
1034836009532	ribonuclease R; Region: RNase_R; TIGR02063
1034836009533	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
1034836009534	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
1034836009535	RNB domain; Region: RNB; pfam00773
1034836009536	S1_RNase_R: RNase R C-terminal S1 domain. RNase R is a processive 3' to 5' exoribonuclease, which is a homolog of RNase II. RNase R degrades RNA with secondary structure having a 3' overhang of at least 7 nucleotides. RNase R and PNPase...; Region: S1_RNase_R; cd04471
1034836009537	RNA binding site [nucleotide binding]; other site
1034836009538	Esterase/lipase [General function prediction only]; Region: COG1647
1034836009539	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
1034836009540	Uncharacterized conserved protein (DUF2048); Region: DUF2048; pfam09752
1034836009541	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1034836009542	salt bridge; other site
1034836009543	non-specific DNA binding site [nucleotide binding]; other site
1034836009544	sequence-specific DNA binding site [nucleotide binding]; other site
1034836009545	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1034836009546	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1034836009547	non-specific DNA binding site [nucleotide binding]; other site
1034836009548	salt bridge; other site
1034836009549	sequence-specific DNA binding site [nucleotide binding]; other site
1034836009550	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1034836009551	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1034836009552	non-specific DNA binding site [nucleotide binding]; other site
1034836009553	salt bridge; other site
1034836009554	sequence-specific DNA binding site [nucleotide binding]; other site
1034836009555	Predicted transcriptional regulators [Transcription]; Region: COG1733
1034836009556	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1034836009557	dimerization interface [polypeptide binding]; other site
1034836009558	putative DNA binding site [nucleotide binding]; other site
1034836009559	putative Zn2+ binding site [ion binding]; other site
1034836009560	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1034836009561	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1034836009562	dimer interface [polypeptide binding]; other site
1034836009563	phosphorylation site [posttranslational modification]
1034836009564	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1034836009565	ATP binding site [chemical binding]; other site
1034836009566	Mg2+ binding site [ion binding]; other site
1034836009567	G-X-G motif; other site
1034836009568	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1034836009569	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1034836009570	active site
1034836009571	phosphorylation site [posttranslational modification]
1034836009572	intermolecular recognition site; other site
1034836009573	dimerization interface [polypeptide binding]; other site
1034836009574	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1034836009575	DNA binding site [nucleotide binding]
1034836009576	lantibiotic protection ABC transporter permease subunit, MutG family; Region: lanti_perm_MutG; TIGR03733
1034836009577	ABC-2 family transporter protein; Region: ABC2_membrane_4; pfam12730
1034836009578	lantibiotic protection ABC transporter permease subunit, MutE/EpiE family; Region: lanti_perm_MutE; TIGR03732
1034836009579	ABC-2 family transporter protein; Region: ABC2_membrane_4; pfam12730
1034836009580	gallidermin-class lantibiotic protection ABC transporter, ATP-binding subunit; Region: galliderm_ABC; TIGR03740
1034836009581	ATP-binding cassette domain of the bacitracin-resistance transporter; Region: ABC_BcrA_bacitracin_resist; cd03268
1034836009582	Walker A/P-loop; other site
1034836009583	ATP binding site [chemical binding]; other site
1034836009584	Q-loop/lid; other site
1034836009585	ABC transporter signature motif; other site
1034836009586	Walker B; other site
1034836009587	D-loop; other site
1034836009588	H-loop/switch region; other site
1034836009589	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1034836009590	dimer interface [polypeptide binding]; other site
1034836009591	conserved gate region; other site
1034836009592	putative PBP binding loops; other site
1034836009593	ABC-ATPase subunit interface; other site
1034836009594	Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) [Cell envelope biogenesis, outer membrane]; Region: OpuBC; COG1732
1034836009595	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1034836009596	dimer interface [polypeptide binding]; other site
1034836009597	conserved gate region; other site
1034836009598	putative PBP binding loops; other site
1034836009599	ABC-ATPase subunit interface; other site
1034836009600	ATP-binding cassette domain of the osmoprotectant transporter; Region: ABC_OpuCA_Osmoprotection; cd03295
1034836009601	glycine betaine/L-proline transport ATP binding subunit; Region: proV; TIGR01186
1034836009602	Walker A/P-loop; other site
1034836009603	ATP binding site [chemical binding]; other site
1034836009604	Q-loop/lid; other site
1034836009605	ABC transporter signature motif; other site
1034836009606	Walker B; other site
1034836009607	D-loop; other site
1034836009608	H-loop/switch region; other site
1034836009609	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in association with the ABC transporter OpuCA. OpuCA is the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing...; Region: CBS_pair_ABC_OpuCA_assoc2; cd04583
1034836009610	Predicted transcriptional regulators [Transcription]; Region: COG1510
1034836009611	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1034836009612	putative DNA binding site [nucleotide binding]; other site
1034836009613	putative Zn2+ binding site [ion binding]; other site
1034836009614	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1034836009615	dimer interface [polypeptide binding]; other site
1034836009616	conserved gate region; other site
1034836009617	putative PBP binding loops; other site
1034836009618	ABC-ATPase subunit interface; other site
1034836009619	Substrate binding domain of ABC-type glycine betaine transport system; Region: OpuAC; pfam04069
1034836009620	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1034836009621	dimer interface [polypeptide binding]; other site
1034836009622	conserved gate region; other site
1034836009623	putative PBP binding loops; other site
1034836009624	ABC-ATPase subunit interface; other site
1034836009625	ATP-binding cassette domain of the osmoprotectant transporter; Region: ABC_OpuCA_Osmoprotection; cd03295
1034836009626	glycine betaine/L-proline transport ATP binding subunit; Region: proV; TIGR01186
1034836009627	Walker A/P-loop; other site
1034836009628	ATP binding site [chemical binding]; other site
1034836009629	Q-loop/lid; other site
1034836009630	ABC transporter signature motif; other site
1034836009631	Walker B; other site
1034836009632	D-loop; other site
1034836009633	H-loop/switch region; other site
1034836009634	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in association with the ABC transporter OpuCA. OpuCA is the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing...; Region: CBS_pair_ABC_OpuCA_assoc2; cd04583
1034836009635	Predicted transcriptional regulators [Transcription]; Region: COG1510
1034836009636	MarR family; Region: MarR_2; pfam12802
1034836009637	membrane protein, MarC family; Region: TIGR00427
1034836009638	potential frameshift: common BLAST hit: gi|154687515|ref|YP_001422676.1| YvbJ
1034836009639	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1034836009640	Coenzyme A binding pocket [chemical binding]; other site
1034836009641	H+ Antiporter protein; Region: 2A0121; TIGR00900
1034836009642	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1034836009643	putative substrate translocation pore; other site
1034836009644	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
1034836009645	Uncharacterized proteins, LmbE homologs [Function unknown]; Region: COG2120
1034836009646	WbqC-like protein family; Region: WbqC; pfam08889
1034836009647	Acetyltransferase (GNAT) domain; Region: Acetyltransf_6; cl17497
1034836009648	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
1034836009649	DegT/DnrJ/EryC1/StrS aminotransferase family; Region: DegT_DnrJ_EryC1; pfam01041
1034836009650	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1034836009651	catalytic residue [active]
1034836009652	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
1034836009653	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1034836009654	NAD(P) binding site [chemical binding]; other site
1034836009655	active site
1034836009656	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
1034836009657	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
1034836009658	inhibitor-cofactor binding pocket; inhibition site
1034836009659	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1034836009660	catalytic residue [active]
1034836009661	UDP-N-acetyl-D-mannosaminuronate dehydrogenase [Cell envelope biogenesis, outer membrane]; Region: WecC; COG0677
1034836009662	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
1034836009663	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
1034836009664	UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain; Region: UDPG_MGDP_dh_C; pfam03720
1034836009665	PA_C5a_like: Protease-associated domain containing proteins like Streptococcus pyogenes C5a peptidase. This group contains various PA domain-containing proteins similar to S. pyogenes C5a, including, i) Vpr, a minor extracellular serine protease from...; Region: PA_C5a_like; cd02133
1034836009666	putative integrin binding motif; other site
1034836009667	PA/protease domain interface [polypeptide binding]; other site
1034836009668	M28 Zn-peptidases include aminopeptidases and carboxypeptidases; Region: M28; cd02690
1034836009669	Peptidase family M28; Region: Peptidase_M28; pfam04389
1034836009670	metal binding site [ion binding]; metal-binding site
1034836009671	enolase; Provisional; Region: eno; PRK00077
1034836009672	Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313
1034836009673	dimer interface [polypeptide binding]; other site
1034836009674	metal binding site [ion binding]; metal-binding site
1034836009675	substrate binding pocket [chemical binding]; other site
1034836009676	Phosphoglyceromutase [Carbohydrate transport and metabolism]; Region: GpmI; COG0696
1034836009677	phosphoglyceromutase; Provisional; Region: PRK05434
1034836009678	Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311
1034836009679	triosephosphate isomerase; Provisional; Region: PRK14565
1034836009680	substrate binding site [chemical binding]; other site
1034836009681	dimer interface [polypeptide binding]; other site
1034836009682	catalytic triad [active]
1034836009683	Phosphoglycerate kinase; Region: PGK; pfam00162
1034836009684	Phosphoglycerate kinase (PGK) is a monomeric enzyme which catalyzes the transfer of the high-energy phosphate group of 1,3-bisphosphoglycerate to ADP, forming ATP and 3-phosphoglycerate. This reaction represents the first of the two substrate-level...; Region: Phosphoglycerate_kinase; cd00318
1034836009685	substrate binding site [chemical binding]; other site
1034836009686	hinge regions; other site
1034836009687	ADP binding site [chemical binding]; other site
1034836009688	catalytic site [active]
1034836009689	Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase [Carbohydrate transport and metabolism]; Region: GapA; COG0057
1034836009690	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
1034836009691	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
1034836009692	Transcriptional regulator, contains sigma factor-related N-terminal domain [Transcription]; Region: DeoR; COG2390
1034836009693	Putative sugar-binding domain; Region: Sugar-bind; pfam04198
1034836009694	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1034836009695	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1034836009696	DNA-binding site [nucleotide binding]; DNA binding site
1034836009697	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1034836009698	Ligand-binding domain of DNA transcription repressor specific for arabinose (AraR) which is a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_AraR; cd01541
1034836009699	putative dimerization interface [polypeptide binding]; other site
1034836009700	putative ligand binding site [chemical binding]; other site
1034836009701	luciferase family oxidoreductase, group 1; Region: oxido_grp_1; TIGR03558
1034836009702	Flavin-utilizing monoxygenases; Region: Flavin_utilizing_monoxygenases; cl07892
1034836009703	Flavin-utilizing monoxygenases; Region: Flavin_utilizing_monoxygenases; cd00347
1034836009704	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1034836009705	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1034836009706	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1034836009707	dimerization interface [polypeptide binding]; other site
1034836009708	EamA-like transporter family; Region: EamA; pfam00892
1034836009709	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
1034836009710	EamA-like transporter family; Region: EamA; pfam00892
1034836009711	gamma-aminobutyrate permease; Region: GABAperm; TIGR01773
1034836009712	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
1034836009713	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
1034836009714	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
1034836009715	putative active site [active]
1034836009716	gluconate kinase, FGGY type; Region: gntK_FGGY; TIGR01314
1034836009717	Gluconate kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_GntK; cd07770
1034836009718	N- and C-terminal domain interface [polypeptide binding]; other site
1034836009719	active site
1034836009720	catalytic site [active]
1034836009721	metal binding site [ion binding]; metal-binding site
1034836009722	carbohydrate binding site [chemical binding]; other site
1034836009723	ATP binding site [chemical binding]; other site
1034836009724	fructuronate transporter; Provisional; Region: PRK10034; cl15264
1034836009725	GntP family permease; Region: GntP_permease; pfam02447
1034836009726	Uncharacterized conserved protein [Function unknown]; Region: COG1556
1034836009727	iron-sulfur cluster-binding protein; Region: TIGR00273
1034836009728	Uncharacterized ACR, YkgG family COG1556; Region: DUF162; pfam02589
1034836009729	Domain of unknown function (DUF3390); Region: DUF3390; pfam11870
1034836009730	CoB--CoM heterodisulfide reductase, subunit B; Region: CoB_CoM_SS_B; TIGR03288
1034836009731	Cysteine-rich domain; Region: CCG; pfam02754
1034836009732	Cysteine-rich domain; Region: CCG; pfam02754
1034836009733	Aspartate/tyrosine/aromatic aminotransferase [Amino acid transport and metabolism]; Region: COG0436
1034836009734	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1034836009735	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1034836009736	homodimer interface [polypeptide binding]; other site
1034836009737	catalytic residue [active]
1034836009738	Transcriptional regulators [Transcription]; Region: FadR; COG2186
1034836009739	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1034836009740	DNA-binding site [nucleotide binding]; DNA binding site
1034836009741	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
1034836009742	L-lactate permease [Energy production and conversion]; Region: LldP; COG1620
1034836009743	L-lactate permease; Region: Lactate_perm; pfam02652
1034836009744	Sigma-54 factor, Activator interacting domain (AID); Region: Sigma54_AID; pfam00309
1034836009745	RNA polymerase sigma-54 factor; Region: rpoN_sigma; TIGR02395
1034836009746	Sigma-54 factor, core binding domain; Region: Sigma54_CBD; pfam04963
1034836009747	Sigma-54, DNA binding domain; Region: Sigma54_DBD; pfam04552
1034836009748	YvfG protein; Region: YvfG; pfam09628
1034836009749	Exopolysaccharide biosynthesis protein [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: COG5039
1034836009750	Polysaccharide pyruvyl transferase; Region: PS_pyruv_trans; pfam04230
1034836009751	Polysaccharide pyruvyl transferase; Region: PS_pyruv_trans; pfam04230
1034836009752	aminotransferase, LLPSF_NHT_00031 family; Region: NHT_00031; TIGR04181
1034836009753	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
1034836009754	inhibitor-cofactor binding pocket; inhibition site
1034836009755	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1034836009756	catalytic residue [active]
1034836009757	Putative Acyltransferase (AT), Left-handed parallel beta-Helix (LbH) domain; This group is composed of mostly uncharacterized proteins containing an N-terminal helical subdomain followed by a LbH domain. The alignment contains 6 turns, each containing...; Region: LbH_AT_putative; cd03360
1034836009758	sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family; Region: NeuD_NnaD; TIGR03570
1034836009759	putative trimer interface [polypeptide binding]; other site
1034836009760	putative CoA binding site [chemical binding]; other site
1034836009761	Bacterial sugar transferase; Region: Bac_transf; pfam02397
1034836009762	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
1034836009763	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cd12082
1034836009764	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
1034836009765	active site
1034836009766	Exopolysaccharide biosynthesis protein [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: COG5039
1034836009767	Polysaccharide pyruvyl transferase; Region: PS_pyruv_trans; pfam04230
1034836009768	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
1034836009769	active site
1034836009770	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1034836009771	This family is most closely related to the GT1 family of glycosyltransferases. capH in Staphylococcus aureus has been shown to be required for the biosynthesis of the type 1 capsular polysaccharide (CP1); Region: GT1_CapH_like; cd03812
1034836009772	putative ADP-binding pocket [chemical binding]; other site
1034836009773	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
1034836009774	Glycosyl transferase family 2; Region: Glycos_transf_2; pfam00535
1034836009775	active site
1034836009776	This family is most closely related to the GT1 family of glycosyltransferases. cap1E in Streptococcus pneumoniae is required for the synthesis of type 1 capsular polysaccharides; Region: GT1_cap1E_like; cd03808
1034836009777	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1034836009778	putative ADP-binding pocket [chemical binding]; other site
1034836009779	Predicted nucleoside-diphosphate sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG1086
1034836009780	UDP-Glcnac (UDP-linked N-acetylglucosamine) inverting 4,6-dehydratase, extended (e) SDRs; Region: UDP_invert_4-6DH_SDR_e; cd05237
1034836009781	NAD(P) binding site [chemical binding]; other site
1034836009782	homodimer interface [polypeptide binding]; other site
1034836009783	substrate binding site [chemical binding]; other site
1034836009784	active site
1034836009785	exopolysaccharide/PEP-CTERM locus tyrosine autokinase; Region: pepcterm_TyrKin; TIGR03018
1034836009786	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
1034836009787	Capsular polysaccharide biosynthesis protein [Cell envelope biogenesis, outer membrane]; Region: COG3944
1034836009788	Chain length determinant protein; Region: Wzz; cl15801
1034836009789	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1034836009790	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1034836009791	non-specific DNA binding site [nucleotide binding]; other site
1034836009792	salt bridge; other site
1034836009793	sequence-specific DNA binding site [nucleotide binding]; other site
1034836009794	Anti-repressor SinI; Region: SinI; pfam08671
1034836009795	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cd00312
1034836009796	Carboxylesterase type B [Lipid metabolism]; Region: PnbA; COG2272
1034836009797	substrate binding pocket [chemical binding]; other site
1034836009798	catalytic triad [active]
1034836009799	RibD C-terminal domain; Region: RibD_C; cl17279
1034836009800	Dihydrofolate reductase [Coenzyme metabolism]; Region: FolA; COG0262
1034836009801	hypothetical protein; Provisional; Region: PRK07236
1034836009802	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme metabolism / Energy production and conversion]; Region: UbiH; COG0654
1034836009803	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
1034836009804	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
1034836009805	Predicted membrane protein [Function unknown]; Region: COG2364
1034836009806	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
1034836009807	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
1034836009808	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1034836009809	Coenzyme A binding pocket [chemical binding]; other site
1034836009810	Phenolic acid decarboxylase (PAD); Region: PA_decarbox; cl01382
1034836009811	hypothetical protein; Provisional; Region: PRK00872
1034836009812	Protein of unknown function (DUF1433); Region: DUF1433; pfam07252
1034836009813	Protein of unknown function (DUF1433); Region: DUF1433; pfam07252
1034836009814	Protein of unknown function (DUF1433); Region: DUF1433; pfam07252
1034836009815	Lipase.  Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface. A typical feature of lipases is "interfacial activation", the process of...; Region: Lipase; cd00741
1034836009816	nucleophilic elbow; other site
1034836009817	catalytic triad; other site
1034836009818	Beta-fructosidases (levanase/invertase) [Carbohydrate transport and metabolism]; Region: SacC; COG1621
1034836009819	Glycosyl hydrolase family 32, beta-fructosidases; Region: GH32_B_Fructosidase; cd08996
1034836009820	substrate binding [chemical binding]; other site
1034836009821	active site
1034836009822	Glycosyl hydrolases family 32 C terminal; Region: Glyco_hydro_32C; pfam08244
1034836009823	galactoside permease; Reviewed; Region: lacY; PRK09528
1034836009824	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1034836009825	putative substrate translocation pore; other site
1034836009826	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1034836009827	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1034836009828	DNA binding site [nucleotide binding]
1034836009829	domain linker motif; other site
1034836009830	Ligand binding domain of the lacI-like transcription regulator from a novel metal-reducing bacterium Alkaliphilus Metalliredigens (strain Qymf) and its close homologs; Region: PBP1_Qymf_like; cd06291
1034836009831	dimerization interface [polypeptide binding]; other site
1034836009832	ligand binding site [chemical binding]; other site
1034836009833	sodium binding site [ion binding]; other site
1034836009834	Clp protease; Region: CLP_protease; pfam00574
1034836009835	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
1034836009836	oligomer interface [polypeptide binding]; other site
1034836009837	active site residues [active]
1034836009838	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1034836009839	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1034836009840	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1034836009841	dimerization interface [polypeptide binding]; other site
1034836009842	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2828
1034836009843	benzoate transport; Region: 2A0115; TIGR00895
1034836009844	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1034836009845	putative substrate translocation pore; other site
1034836009846	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1034836009847	TIGR00730 family protein; Region: TIGR00730
1034836009848	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain superfamily; Region: NTP-PPase; cd11523
1034836009849	metal binding site [ion binding]; metal-binding site
1034836009850	Sulfate permease and related transporters (MFS superfamily) [Inorganic ion transport and metabolism]; Region: SUL1; COG0659
1034836009851	Sulfate transporter N-terminal domain with GLY motif; Region: Sulfate_tra_GLY; pfam13792
1034836009852	Sulfate transporter family; Region: Sulfate_transp; pfam00916
1034836009853	Sulphate Transporter and Anti-Sigma factor antagonist domain of SulP-like sulfate transporters, plays a role in the function and regulation of the transport activity, proposed general NTP binding function; Region: STAS_SulP_like_sulfate_transporter; cd07042
1034836009854	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeD; cd03379
1034836009855	active site clefts [active]
1034836009856	zinc binding site [ion binding]; other site
1034836009857	dimer interface [polypeptide binding]; other site
1034836009858	Lactate dehydrogenase and related dehydrogenases [Energy production and conversion / Coenzyme metabolism / General function prediction only]; Region: LdhA; COG1052
1034836009859	D-glycerate dehydrogenase/hydroxypyruvate reductase (GDH); Region: GDH; cd05301
1034836009860	dimerization interface [polypeptide binding]; other site
1034836009861	ligand binding site [chemical binding]; other site
1034836009862	NADP binding site [chemical binding]; other site
1034836009863	catalytic site [active]
1034836009864	Barnase, a member of the family of homologous microbial ribonucleases, catalyses the cleavage of single-stranded RNA via a two-step mechanism thought to be similar to that of pancreatic ribonuclease. The mechanism involves a transesterification to give a...; Region: barnase; cd00933
1034836009865	active site
1034836009866	Arylamine N-acetyltransferase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: NhoA; COG2162
1034836009867	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
1034836009868	dimerization domain swap beta strand [polypeptide binding]; other site
1034836009869	regulatory protein interface [polypeptide binding]; other site
1034836009870	active site
1034836009871	regulatory phosphorylation site [posttranslational modification]; other site
1034836009872	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1481
1034836009873	Sporulation Regulator WhiA N terminal; Region: WhiA_N; pfam10298
1034836009874	conserved hypothetical protein, cofD-related; Region: CofD_related; TIGR01826
1034836009875	family of mostly uncharacterized proteins similar to B.subtilis YvcK; Region: YvcK_like; cd07187
1034836009876	phosphate binding site [ion binding]; other site
1034836009877	putative substrate binding pocket [chemical binding]; other site
1034836009878	dimer interface [polypeptide binding]; other site
1034836009879	glmZ(sRNA)-inactivating NTPase; Provisional; Region: PRK05416
1034836009880	MutT homolog-1 (MTH1) is a member of the Nudix hydrolase superfamily. MTH1, the mammalian counterpart of MutT, hydrolyzes oxidized purine nucleoside triphosphates, such as 8-oxo-dGTP and 2-hydroxy-ATP, to monophosphates, thereby preventing the...; Region: MTH1; cd03427
1034836009881	putative active site [active]
1034836009882	nucleotide binding site [chemical binding]; other site
1034836009883	nudix motif; other site
1034836009884	putative metal binding site [ion binding]; other site
1034836009885	thioredoxin-disulfide reductase; Region: TRX_reduct; TIGR01292
1034836009886	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1034836009887	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1034836009888	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3883
1034836009889	GDP/GTP exchange factor Sec2p; Region: Sec2p; pfam06428
1034836009890	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
1034836009891	NlpC/P60 family; Region: NLPC_P60; pfam00877
1034836009892	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1034836009893	binding surface
1034836009894	Tetratricopeptide repeat; Region: TPR_16; pfam13432
1034836009895	TPR motif; other site
1034836009896	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1034836009897	TPR motif; other site
1034836009898	binding surface
1034836009899	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1034836009900	dimer interface [polypeptide binding]; other site
1034836009901	phosphorylation site [posttranslational modification]
1034836009902	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1034836009903	ATP binding site [chemical binding]; other site
1034836009904	Mg2+ binding site [ion binding]; other site
1034836009905	G-X-G motif; other site
1034836009906	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1034836009907	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1034836009908	active site
1034836009909	phosphorylation site [posttranslational modification]
1034836009910	intermolecular recognition site; other site
1034836009911	dimerization interface [polypeptide binding]; other site
1034836009912	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1034836009913	DNA binding site [nucleotide binding]
1034836009914	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1034836009915	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1034836009916	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1034836009917	Walker A/P-loop; other site
1034836009918	ATP binding site [chemical binding]; other site
1034836009919	Q-loop/lid; other site
1034836009920	ABC transporter signature motif; other site
1034836009921	Walker B; other site
1034836009922	D-loop; other site
1034836009923	H-loop/switch region; other site
1034836009924	Phosphoribosyl-AMP cyclohydrolase [Amino acid transport and metabolism]; Region: HisI; COG0139
1034836009925	bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein; Reviewed; Region: PRK02759
1034836009926	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in Escherichia coli phosphoribosyl-ATP pyrophosphohydrolase (HisIE or PRATP-PH) and its homologs; Region: NTP-PPase_HisIE_like; cd11534
1034836009927	metal binding site [ion binding]; metal-binding site
1034836009928	The cyclase subunit of imidazoleglycerol phosphate synthase (HisF). Imidazole glycerol phosphate synthase (IGPS) catalyzes the fifth step of histidine biosynthesis, the formation of the imidazole ring. IGPS converts N1-(5'-phosphoribulosyl)...; Region: HisF; cd04731
1034836009929	Histidine biosynthesis protein; Region: His_biosynth; pfam00977
1034836009930	substrate binding site [chemical binding]; other site
1034836009931	glutamase interaction surface [polypeptide binding]; other site
1034836009932	HisA.  Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase catalyzes the fourth step in histidine biosynthesis, an isomerisation of the aminoaldose moiety of ProFAR to the aminoketose of PRFAR (N-(5'-phospho-D-1...; Region: HisA; cd04732
1034836009933	phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; Region: TIGR00007
1034836009934	catalytic residues [active]
1034836009935	imidazole glycerol phosphate synthase subunit HisH; Provisional; Region: hisH; PRK13141
1034836009936	Type 1 glutamine amidotransferase (GATase1) domain found in imidazole glycerol phosphate synthase (IGPS); Region: GATase1_IGP_Synthase; cd01748
1034836009937	putative active site [active]
1034836009938	oxyanion strand; other site
1034836009939	catalytic triad [active]
1034836009940	Imidazoleglycerol-phosphate dehydratase; Region: IGPD; cd07914
1034836009941	putative active site pocket [active]
1034836009942	4-fold oligomerization interface [polypeptide binding]; other site
1034836009943	metal binding residues [ion binding]; metal-binding site
1034836009944	3-fold/trimer interface [polypeptide binding]; other site
1034836009945	Histidinol dehydrogenase, HisD, E.C 1.1.1.23. Histidinol dehydrogenase catalyzes the last two steps in the L-histidine biosynthesis pathway, which is conserved in bacteria, archaea, fungi, and plants. These last two steps are (i) the NAD-dependent...; Region: Histidinol_dh; cd06572
1034836009946	histidinol dehydrogenase; Region: hisD; TIGR00069
1034836009947	NAD binding site [chemical binding]; other site
1034836009948	dimerization interface [polypeptide binding]; other site
1034836009949	product binding site; other site
1034836009950	substrate binding site [chemical binding]; other site
1034836009951	zinc binding site [ion binding]; other site
1034836009952	catalytic residues [active]
1034836009953	ATP phosphoribosyltransferase [Amino acid transport and metabolism]; Region: HisG; COG0040
1034836009954	ATP phosphoribosyltransferase catalytic subunit; Reviewed; Region: hisG; PRK01686
1034836009955	ATP phosphoribosyltransferase regulatory subunit; Provisional; Region: hisZ; PRK12292
1034836009956	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
1034836009957	dimer interface [polypeptide binding]; other site
1034836009958	motif 1; other site
1034836009959	active site
1034836009960	motif 2; other site
1034836009961	motif 3; other site
1034836009962	A sub-family of peptidase family C39. Peptidase family C39 mostly contains bacteriocin-processing endopeptidases from bacteria. The cysteine peptidases in family C39 cleave the "double-glycine" leader peptides from the precursors of various...; Region: Peptidase_C39A; cd02549
1034836009963	putative active site [active]
1034836009964	Acetyltransferase (isoleucine patch superfamily) [General function prediction only]; Region: WbbJ; COG0110
1034836009965	Maltose O-acyltransferase (MAT)-like: This family is composed of maltose O-acetyltransferase, galactoside O-acetyltransferase (GAT), xenobiotic acyltransferase (XAT) and similar proteins. MAT and GAT catalyze the CoA-dependent acetylation of the...; Region: LbH_MAT_like; cd04647
1034836009966	trimer interface [polypeptide binding]; other site
1034836009967	active site
1034836009968	substrate binding site [chemical binding]; other site
1034836009969	CoA binding site [chemical binding]; other site
1034836009970	pyrophosphatase PpaX; Provisional; Region: PRK13288
1034836009971	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cl17915
1034836009972	motif I; other site
1034836009973	active site
1034836009974	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1034836009975	motif II; other site
1034836009976	prolipoprotein diacylglyceryl transferase; Reviewed; Region: PRK12437
1034836009977	HPr kinase/phosphorylase; Provisional; Region: PRK05428
1034836009978	HPr Serine kinase N terminus; Region: Hpr_kinase_N; pfam02603
1034836009979	HprK/P, the bifunctional histidine-containing protein kinase/phosphatase, controls the phosphorylation state of the phosphocarrier protein HPr and regulates the utilization of carbon sources by gram-positive bacteria. It catalyzes both the ATP-dependent...; Region: HprK_C; cd01918
1034836009980	Hpr binding site; other site
1034836009981	active site
1034836009982	homohexamer subunit interaction site [polypeptide binding]; other site
1034836009983	N-acetylglucosamine-6-phosphate deacetylase; Region: nagA; TIGR00221
1034836009984	N-acetylglucosamine-6-phosphate deacetylase, NagA, catalyzes the hydrolysis of the N-acetyl group of N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to glucosamine 6-phosphate and acetate. This is the first committed step in the biosynthetic pathway to...; Region: NagA; cd00854
1034836009985	active site
1034836009986	dimer interface [polypeptide binding]; other site
1034836009987	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
1034836009988	GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399
1034836009989	active site
1034836009990	trimer interface [polypeptide binding]; other site
1034836009991	allosteric site; other site
1034836009992	active site lid [active]
1034836009993	hexamer (dimer of trimers) interface [polypeptide binding]; other site
1034836009994	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
1034836009995	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1034836009996	DNA-binding site [nucleotide binding]; DNA binding site
1034836009997	The UbiC transcription regulator-associated (UTRA) domain is a conserved ligand-binding domain; Region: UTRA; smart00866
1034836009998	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1034836009999	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1034836010000	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1034836010001	Bacillus subtilis YvnB and related proteins, metallophosphatase domain; Region: MPP_YvnB; cd07399
1034836010002	putative active site [active]
1034836010003	putative metal binding site [ion binding]; other site
1034836010004	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
1034836010005	Predicted membrane protein [Function unknown]; Region: COG1950
1034836010006	PspC domain; Region: PspC; pfam04024
1034836010007	Uncharacterized conserved protein [Function unknown]; Region: COG3595
1034836010008	Domain of unknown function (DUF4098); Region: DUF4098; pfam13345
1034836010009	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
1034836010010	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
1034836010011	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
1034836010012	ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271
1034836010013	excinuclease ABC subunit B; Provisional; Region: PRK05298
1034836010014	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1034836010015	ATP binding site [chemical binding]; other site
1034836010016	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1034836010017	nucleotide binding region [chemical binding]; other site
1034836010018	ATP-binding site [chemical binding]; other site
1034836010019	Ultra-violet resistance protein B; Region: UvrB; pfam12344
1034836010020	Uncharacterized protein conserved in bacteria (DUF2198); Region: DUF2198; pfam09964
1034836010021	phosphoenolpyruvate synthase; Validated; Region: PRK06241
1034836010022	Pyruvate phosphate dikinase, PEP/pyruvate binding domain; Region: PPDK_N; pfam01326
1034836010023	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
1034836010024	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1034836010025	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1034836010026	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1034836010027	putative substrate translocation pore; other site
1034836010028	40-residue YVTN family beta-propeller repeat; Region: beta_rpt_yvtn; TIGR02276
1034836010029	Uncharacterized conserved protein [Function unknown]; Region: COG3391
1034836010030	40-residue YVTN family beta-propeller repeat; Region: beta_rpt_yvtn; TIGR02276
1034836010031	40-residue YVTN family beta-propeller repeat; Region: beta_rpt_yvtn; TIGR02276
1034836010032	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain [Posttranslational modification, protein turnover, chaperones]; Region: DegQ; COG0265
1034836010033	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1034836010034	C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526
1034836010035	C-terminal peptidase (prc); Region: prc; TIGR00225
1034836010036	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
1034836010037	protein binding site [polypeptide binding]; other site
1034836010038	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
1034836010039	Catalytic dyad [active]
1034836010040	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
1034836010041	Protein of unknown function (DUF1565); Region: DUF1565; pfam07602
1034836010042	Right handed beta helix region; Region: Beta_helix; pfam13229
1034836010043	Cell division protein [Cell division and chromosome partitioning]; Region: FtsX; COG2177
1034836010044	cell division ABC transporter subunit FtsX; Provisional; Region: ftsX; PRK11026
1034836010045	Predicted ATPase involved in cell division [Cell division and chromosome partitioning]; Region: FtsE; COG2884
1034836010046	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1034836010047	Walker A/P-loop; other site
1034836010048	ATP binding site [chemical binding]; other site
1034836010049	Q-loop/lid; other site
1034836010050	ABC transporter signature motif; other site
1034836010051	Walker B; other site
1034836010052	D-loop; other site
1034836010053	H-loop/switch region; other site
1034836010054	Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010
1034836010055	Cytochrome C oxidase, cbb3-type, subunit III; Region: Cytochrome_CBB3; pfam13442
1034836010056	Uncharacterized conserved protein [Function unknown]; Region: COG1284
1034836010057	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
1034836010058	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
1034836010059	Uncharacterized protein conserved in bacteria (DUF2179); Region: DUF2179; pfam10035
1034836010060	peptide chain release factor 2; Provisional; Region: PRK06746
1034836010061	This domain is found in peptide chain release factors; Region: PCRF; smart00937
1034836010062	RF-1 domain; Region: RF-1; pfam00472
1034836010063	preprotein translocase subunit SecA; Reviewed; Region: PRK12904
1034836010064	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
1034836010065	SecA preprotein cross-linking domain; Region: SecA_PP_bind; smart00958
1034836010066	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cl17351
1034836010067	nucleotide binding region [chemical binding]; other site
1034836010068	ATP-binding site [chemical binding]; other site
1034836010069	SEC-C motif; Region: SEC-C; pfam02810
1034836010070	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
1034836010071	30S subunit binding site; other site
1034836010072	Flagellar protein FliT; Region: FliT; pfam05400
1034836010073	flagellar protein FliS; Validated; Region: fliS; PRK05685
1034836010074	flagellar capping protein; Validated; Region: fliD; PRK07737
1034836010075	Flagellar hook-associated protein 2 C-terminus; Region: FliD_N; pfam02465
1034836010076	Flagellar hook-associated protein 2 C-terminus; Region: FliD_C; pfam07195
1034836010077	flagellin; Provisional; Region: PRK12804
1034836010078	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
1034836010079	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
1034836010080	carbon storage regulator; Provisional; Region: PRK01712
1034836010081	flagellar assembly protein FliW; Provisional; Region: PRK13285
1034836010082	flagellar hook-associated protein FlgL; Validated; Region: flgL; PRK07701
1034836010083	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
1034836010084	flagellar hook-associated protein FlgK; Validated; Region: flgK; PRK07739
1034836010085	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
1034836010086	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1034836010087	FlgN protein; Region: FlgN; pfam05130
1034836010088	flagellar biosynthesis anti-sigma factor FlgM; Region: FlgM_jcvi; TIGR03824
1034836010089	flagellar operon protein TIGR03826; Region: YvyF
1034836010090	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1034836010091	active site
1034836010092	Late competence development protein ComFB; Region: ComFB; pfam10719
1034836010093	Superfamily II DNA/RNA helicase required for DNA uptake (late competence protein) [DNA replication, recombination, and repair]; Region: comFA; COG4098
1034836010094	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1034836010095	ATP binding site [chemical binding]; other site
1034836010096	putative Mg++ binding site [ion binding]; other site
1034836010097	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1034836010098	nucleotide binding region [chemical binding]; other site
1034836010099	ATP-binding site [chemical binding]; other site
1034836010100	EDD domain protein, DegV family; Region: DegV; TIGR00762
1034836010101	Uncharacterized protein, DegV family COG1307; Region: DegV; pfam02645
1034836010102	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1034836010103	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1034836010104	active site
1034836010105	phosphorylation site [posttranslational modification]
1034836010106	intermolecular recognition site; other site
1034836010107	dimerization interface [polypeptide binding]; other site
1034836010108	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1034836010109	DNA binding residues [nucleotide binding]
1034836010110	dimerization interface [polypeptide binding]; other site
1034836010111	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG4585
1034836010112	Histidine kinase; Region: HisKA_3; pfam07730
1034836010113	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1034836010114	ATP binding site [chemical binding]; other site
1034836010115	Mg2+ binding site [ion binding]; other site
1034836010116	G-X-G motif; other site
1034836010117	uncharacterized protein, YigZ family; Region: IMPACT_YIGZ; TIGR00257
1034836010118	Uncharacterized protein family UPF0029; Region: UPF0029; pfam01205
1034836010119	Domain of unknown function (DUF1949); Region: DUF1949; pfam09186
1034836010120	Transcriptional regulator [Transcription]; Region: LytR; COG1316
1034836010121	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase [Cell envelope biogenesis, outer membrane]; Region: Rfe; COG0472
1034836010122	This subfamily contains Escherichia coli WecA, Bacillus subtilis TagO and related proteins. WecA is an UDP-N-acetylglucosamine (GlcNAc):undecaprenyl-phosphate (Und-P) GlcNAc-1-phosphate transferase that catalyzes the formation of a phosphodiester bond...; Region: GT_WecA_like; cd06853
1034836010123	Mg++ binding site [ion binding]; other site
1034836010124	putative catalytic motif [active]
1034836010125	substrate binding site [chemical binding]; other site
1034836010126	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: GT1_like_1; cd04950
1034836010127	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1034836010128	putative homodimer interface [polypeptide binding]; other site
1034836010129	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
1034836010130	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
1034836010131	active site
1034836010132	Chain length determinant protein; Region: Wzz; cl15801
1034836010133	O-Antigen ligase; Region: Wzy_C; pfam04932
1034836010134	Predicted UDP-glucose 6-dehydrogenase [Cell envelope biogenesis, outer membrane]; Region: Ugd; COG1004
1034836010135	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
1034836010136	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
1034836010137	UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain; Region: UDPG_MGDP_dh_C; pfam03720
1034836010138	This family is most closely related to the GT1 family of glycosyltransferases. wlbH in Bordetella parapertussis has been shown to be required for the biosynthesis of a trisaccharide that, when attached to the B. pertussis lipopolysaccharide (LPS) core; Region: GT1_wlbH_like; cd03798
1034836010139	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1034836010140	colanic acid exporter; Provisional; Region: PRK10459
1034836010141	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_tuaB_like; cd13127
1034836010142	exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; Region: EPS_sugtrans; TIGR03025
1034836010143	Bacterial sugar transferase; Region: Bac_transf; pfam02397
1034836010144	Putative cell wall-binding domain [Cell envelope biogenesis, outer membrane]; Region: LytB; COG2247
1034836010145	Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122
1034836010146	Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122
1034836010147	Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122
1034836010148	N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: AmiC; COG0860
1034836010149	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
1034836010150	active site
1034836010151	metal binding site [ion binding]; metal-binding site
1034836010152	Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122
1034836010153	Putative cell wall-binding domain [Cell envelope biogenesis, outer membrane]; Region: LytB; COG2247
1034836010154	Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122
1034836010155	Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122
1034836010156	Stage II sporulation protein; Region: SpoIID; pfam08486
1034836010157	SpoIID/LytB domain; Region: SpoIID_LytB; TIGR02669
1034836010158	Copper binding periplasmic protein CusF; Region: CusF_Ec; cl02363
1034836010159	membrane-bound transcriptional regulator LytR; Provisional; Region: PRK09379
1034836010160	UDP-N-acetylglucosamine 2-epimerase; Region: wecB; TIGR00236
1034836010161	Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase  family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786
1034836010162	active site
1034836010163	homodimer interface [polypeptide binding]; other site
1034836010164	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
1034836010165	dTDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane]; Region: RfbA; COG1209
1034836010166	active site
1034836010167	tetramer interface; other site
1034836010168	ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: TagH; COG1134
1034836010169	ATP-binding cassette component of polysaccharide transport system; Region: ABC_KpsT_Wzt; cd03220
1034836010170	Walker A/P-loop; other site
1034836010171	ATP binding site [chemical binding]; other site
1034836010172	Q-loop/lid; other site
1034836010173	ABC transporter signature motif; other site
1034836010174	Walker B; other site
1034836010175	D-loop; other site
1034836010176	H-loop/switch region; other site
1034836010177	ABC-type polysaccharide/polyol phosphate export systems, permease component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: TagG; COG1682
1034836010178	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
1034836010179	Putative glycosyl/glycerophosphate transferases involved in teichoic acid biosynthesis TagF/TagB/EpsJ/RodC [Cell envelope biogenesis, outer membrane]; Region: TagB; COG1887
1034836010180	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase; Region: Glyphos_transf; pfam04464
1034836010181	Domain of unknown function (DUF1975); Region: DUF1975; pfam09318
1034836010182	This family is most closely related to the GT1 family of glycosyltransferases and is named after gtfA in Streptococcus gordonii, where it plays a role in the O-linked glycosylation of GspB, a cell surface glycoprotein involved in platelet binding.  In...; Region: GT1_gtfA_like; cd04949
1034836010183	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1034836010184	glycerol-3-phosphate cytidylyltransferase; Region: G3P_Cytidylyltransferase; cd02171
1034836010185	Cytidylyltransferase; Region: CTP_transf_2; pfam01467
1034836010186	active site
1034836010187	Teichoic acid biosynthesis proteins [Cell envelope biogenesis, outer membrane]; Region: WecG; COG1922
1034836010188	The glycosyltransferase WecG/TagA superfamily contains Escherichia coli WecG, Bacillus subtilis TagA and related proteins. E. coli WecG is believed to be a UDP-N-acetyl-D-mannosaminuronic acid transferase, and is involved in enterobacterial common...; Region: Glyco_transf_WecG_TagA; cd06533
1034836010189	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase; Region: Glyphos_transf; pfam04464
1034836010190	Putative glycosyl/glycerophosphate transferases involved in teichoic acid biosynthesis TagF/TagB/EpsJ/RodC [Cell envelope biogenesis, outer membrane]; Region: TagB; COG1887
1034836010191	Beta- N-acetylglucosaminidase [Carbohydrate transport and metabolism]; Region: LytD; COG4193
1034836010192	Bacterial SH3 domain; Region: SH3_3; pfam08239
1034836010193	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase; Region: Glucosaminidase; cl17361
1034836010194	Phosphomannose isomerase [Carbohydrate transport and metabolism]; Region: ManA; COG1482
1034836010195	mannose-6-phosphate isomerase, class I; Region: manA; TIGR00218
1034836010196	Bacillus/Clostridium GerA spore germination protein; Region: GerA; pfam03323
1034836010197	Spore germination protein; Region: Spore_permease; pfam03845
1034836010198	germination protein, Ger(x)C family; Region: spore_ger_x_C; TIGR02887
1034836010199	Spore germination B3/ GerAC like, C-terminal; Region: Spore_GerAC; pfam05504
1034836010200	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
1034836010201	Subfamily of Glycosyltransferase Family GT2 of unknown function; Region: GT_2_like_c; cd04186
1034836010202	Probable Catalytic site; other site
1034836010203	metal-binding site
1034836010204	Methyltransferase domain; Region: Methyltransf_23; pfam13489
1034836010205	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1034836010206	S-adenosylmethionine binding site [chemical binding]; other site
1034836010207	Sugar (and other) transporter; Region: Sugar_tr; pfam00083
1034836010208	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1034836010209	putative substrate translocation pore; other site
1034836010210	Transcriptional regulator [Transcription]; Region: LytR; COG1316
1034836010211	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1034836010212	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
1034836010213	active site
1034836010214	motif I; other site
1034836010215	motif II; other site
1034836010216	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1034836010217	SH3 domain protein; Region: SH3_and_anchor; TIGR04211
1034836010218	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
1034836010219	NlpC/P60 family; Region: NLPC_P60; pfam00877
1034836010220	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
1034836010221	NlpC/P60 family; Region: NLPC_P60; pfam00877
1034836010222	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
1034836010223	NlpC/P60 family; Region: NLPC_P60; pfam00877
1034836010224	Putative enzyme of poly-gamma-glutamate biosynthesis (capsule formation) [Cell envelope biogenesis, outer membrane]; Region: PgsA; COG2843
1034836010225	CapA and related proteins, metallophosphatase domain; Region: MPP_CapA; cd07381
1034836010226	putative active site [active]
1034836010227	putative metal binding site [ion binding]; other site
1034836010228	Capsule biosynthesis CapC; Region: Caps_synth_CapC; cl14855
1034836010229	poly-gamma-glutamate synthase PgsB/CapB; Region: poly_gGlu_PgsB; TIGR04012
1034836010230	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1034836010231	Bacillus/Clostridium GerA spore germination protein; Region: GerA; pfam03323
1034836010232	Spore germination protein; Region: Spore_permease; cl17796
1034836010233	germination protein, Ger(x)C family; Region: spore_ger_x_C; TIGR02887
1034836010234	Spore germination B3/ GerAC like, C-terminal; Region: Spore_GerAC; pfam05504
1034836010235	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1034836010236	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1034836010237	DNA binding site [nucleotide binding]
1034836010238	domain linker motif; other site
1034836010239	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
1034836010240	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1034836010241	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
1034836010242	substrate binding site [chemical binding]; other site
1034836010243	dimer interface [polypeptide binding]; other site
1034836010244	ATP binding site [chemical binding]; other site
1034836010245	D-ribose pyranase; Provisional; Region: PRK11797
1034836010246	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
1034836010247	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1034836010248	Walker A/P-loop; other site
1034836010249	ATP binding site [chemical binding]; other site
1034836010250	Q-loop/lid; other site
1034836010251	ABC transporter signature motif; other site
1034836010252	Walker B; other site
1034836010253	D-loop; other site
1034836010254	H-loop/switch region; other site
1034836010255	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1034836010256	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1034836010257	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1034836010258	TM-ABC transporter signature motif; other site
1034836010259	D-ribose transporter subunit RbsB; Provisional; Region: PRK10653
1034836010260	Periplasmic sugar-binding domain of the thermophilic Thermoanaerobacter tengcongensis ribose binding protein (ttRBP) and its mesophilic homologs; Region: PBP1_ribose_binding; cd06323
1034836010261	ligand binding site [chemical binding]; other site
1034836010262	dimerization interface [polypeptide binding]; other site
1034836010263	Bacterial SH3 domain homologues; Region: SH3b; smart00287
1034836010264	Flavodoxin-like fold; Region: Flavodoxin_2; pfam02525
1034836010265	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
1034836010266	alpha-acetolactate decarboxylase; Region: acetolac_decarb; TIGR01252
1034836010267	acetolactate synthase; Reviewed; Region: PRK08617
1034836010268	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
1034836010269	PYR/PP interface [polypeptide binding]; other site
1034836010270	dimer interface [polypeptide binding]; other site
1034836010271	TPP binding site [chemical binding]; other site
1034836010272	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1034836010273	Thiamine pyrophosphate (TPP) family, Acetolactate synthase (ALS) subfamily, TPP-binding module; composed of proteins similar to Klebsiella pneumoniae ALS, a catabolic enzyme required for butanediol fermentation. ALS catalyzes the conversion of 2...; Region: TPP_ALS; cd02010
1034836010274	TPP-binding site [chemical binding]; other site
1034836010275	dimer interface [polypeptide binding]; other site
1034836010276	DNA-binding transcriptional regulator HcaR; Provisional; Region: PRK09906
1034836010277	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1034836010278	The C-terminal substrate binding domain of LysR-type trnascriptional regulator AlsR, which regulates acetoin formation under stationary phase growth conditions; contains the type 2 periplasmic binding fold; Region: PBP2_AlsR; cd08452
1034836010279	putative dimerization interface [polypeptide binding]; other site
1034836010280	putative substrate binding pocket [chemical binding]; other site
1034836010281	Anion permease ArsB.  These permeases have been shown to export arsenate and antimonite in eubacteria and archaea.  A typical ArsB permease contains 8-13 transmembrane helices and can function either independently as a chemiosmotic transporter or as a...; Region: ArsB_permease; cd01118
1034836010282	Na+/H+ antiporter NhaD and related arsenite permeases [Inorganic ion transport and metabolism]; Region: ArsB; COG1055
1034836010283	transmembrane helices; other site
1034836010284	CotH protein; Region: CotH; pfam08757
1034836010285	Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family [General function prediction only]; Region: COG1853
1034836010286	Gamma-glutamyltransferase [Amino acid transport and metabolism]; Region: Ggt; COG0405
1034836010287	gamma-glutamyltranspeptidase; Region: g_glut_trans; TIGR00066
1034836010288	Transcriptional regulators [Transcription]; Region: Lrp; COG1522
1034836010289	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1034836010290	putative DNA binding site [nucleotide binding]; other site
1034836010291	putative Zn2+ binding site [ion binding]; other site
1034836010292	AsnC family; Region: AsnC_trans_reg; pfam01037
1034836010293	Chromate transport protein ChrA [Inorganic ion transport and metabolism]; Region: ChrA; COG2059
1034836010294	Chromate transport protein ChrA [Inorganic ion transport and metabolism]; Region: ChrA; COG2059
1034836010295	SMI1 / KNR4 family; Region: SMI1_KNR4; smart00860
1034836010296	SUKH-4 immunity protein; Region: SUKH-4; pfam14435
1034836010297	LXG domain of WXG superfamily; Region: LXG; pfam04740
1034836010298	A pre-toxin domain with the TG motif; Region: PT-TG; pfam14449
1034836010299	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3878
1034836010300	Predicted UDP-glucose 6-dehydrogenase [Cell envelope biogenesis, outer membrane]; Region: Ugd; COG1004
1034836010301	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
1034836010302	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
1034836010303	UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain; Region: UDPG_MGDP_dh_C; pfam03720
1034836010304	Capsular polysaccharide biosynthesis protein [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: CapC; COG4464
1034836010305	capsular exopolysaccharide family; Region: eps_fam; TIGR01007
1034836010306	ArsA ATPase functionas as an efflux pump located on the inner membrane of the cell. This ATP-driven oxyanion pump catalyzes the extrusion of arsenite, antimonite and arsenate. Maintenance of a low intracellular concentration of oxyanion produces...; Region: ArsA; cd02035
1034836010307	Nucleotide binding site [chemical binding]; other site
1034836010308	DTAP/Switch II; other site
1034836010309	Switch I; other site
1034836010310	Chain length determinant protein; Region: Wzz; cl15801
1034836010311	SWIM zinc finger; Region: SWIM; pfam04434
1034836010312	SNF2 Helicase protein; Region: DUF3670; pfam12419
1034836010313	SNF2 family N-terminal domain; Region: SNF2_N; pfam00176
1034836010314	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1034836010315	ATP binding site [chemical binding]; other site
1034836010316	putative Mg++ binding site [ion binding]; other site
1034836010317	Superfamily II DNA and RNA helicases [DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis]; Region: SrmB; COG0513
1034836010318	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1034836010319	nucleotide binding region [chemical binding]; other site
1034836010320	ATP-binding site [chemical binding]; other site
1034836010321	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1034836010322	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
1034836010323	active site
1034836010324	motif I; other site
1034836010325	motif II; other site
1034836010326	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1034836010327	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1034836010328	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
1034836010329	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1034836010330	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
1034836010331	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
1034836010332	dimer interface [polypeptide binding]; other site
1034836010333	ssDNA binding site [nucleotide binding]; other site
1034836010334	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1034836010335	YwpF-like protein; Region: YwpF; pfam14183
1034836010336	large-conductance mechanosensitive channel; Provisional; Region: mscL; PRK13955
1034836010337	large-conductance mechanosensitive channel; Reviewed; Region: mscL; PRK00567
1034836010338	FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid...; Region: FabZ; cd01288
1034836010339	Tetratricopeptide repeat; Region: TPR_12; pfam13424
1034836010340	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1034836010341	binding surface
1034836010342	TPR motif; other site
1034836010343	Tetratricopeptide repeat; Region: TPR_12; pfam13424
1034836010344	Flagellar basal body rod protein [Cell motility and secretion]; Region: FlgG; COG4786
1034836010345	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
1034836010346	flagellar basal-body rod protein FlgF; Region: flgF; TIGR02490
1034836010347	Flagellar basal body rod protein [Cell motility and secretion]; Region: FlgG; COG4786
1034836010348	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
1034836010349	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1034836010350	rod shape-determining protein Mbl; Provisional; Region: PRK13928
1034836010351	MreB and similar proteins; Region: MreB_like; cd10225
1034836010352	nucleotide binding site [chemical binding]; other site
1034836010353	Mg binding site [ion binding]; other site
1034836010354	putative protofilament interaction site [polypeptide binding]; other site
1034836010355	RodZ interaction site [polypeptide binding]; other site
1034836010356	Stage III sporulation protein D; Region: SpoIIID; pfam12116
1034836010357	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1034836010358	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1034836010359	putative Zn2+ binding site [ion binding]; other site
1034836010360	putative DNA binding site [nucleotide binding]; other site
1034836010361	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1034836010362	putative substrate translocation pore; other site
1034836010363	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1034836010364	uncharacterized nucleobase-cation-symport-1 (NCS1) transporter subfamily, YbbW-like; solute-binding domain; Region: SLC-NCS1sbd_YbbW-like; cd11485
1034836010365	Permease for cytosine/purines, uracil, thiamine, allantoin; Region: Transp_cyt_pur; pfam02133
1034836010366	Na binding site [ion binding]; other site
1034836010367	putative substrate binding site [chemical binding]; other site
1034836010368	potential frameshift: common BLAST hit: gi|154687765|ref|YP_001422926.1| YwoD
1034836010369	Isochorismatase family; Region: Isochorismatase; pfam00857
1034836010370	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cd00431
1034836010371	catalytic triad [active]
1034836010372	conserved cis-peptide bond; other site
1034836010373	Ammonia permease [Inorganic ion transport and metabolism]; Region: AmtB; COG0004
1034836010374	Nitrogen regulatory protein PII [Amino acid transport and metabolism]; Region: GlnK; COG0347
1034836010375	Nitrogen regulatory protein P-II; Region: P-II; smart00938
1034836010376	cell division protein FtsW; Region: ftsW; TIGR02614
1034836010377	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
1034836010378	PAP2_like proteins, BcrC_like subfamily. Several members of this family have been annotated as bacitracin transport permeases, as it was suspected that they form the permease component of an ABC transporter system. It was shown, however, that BcrC from...; Region: PAP2_BcrC_like; cd03385
1034836010379	active site
1034836010380	VanZ like family; Region: VanZ; pfam04892
1034836010381	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
1034836010382	Peptidase family M23; Region: Peptidase_M23; pfam01551
1034836010383	Sortase and related acyltransferases [Cell envelope biogenesis, outer membrane]; Region: COG1247
1034836010384	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1034836010385	Coenzyme A binding pocket [chemical binding]; other site
1034836010386	cardiolipin synthase; Region: bac_cardiolipin; TIGR04265
1034836010387	Phospholipase_D-nuclease N-terminal; Region: PLDc_N; pfam13396
1034836010388	Catalytic domain, repeat 1, of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_1; cd09110
1034836010389	putative active site [active]
1034836010390	catalytic site [active]
1034836010391	catalytic domain repeat 2 of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_2; cd09112
1034836010392	putative active site [active]
1034836010393	catalytic site [active]
1034836010394	biliverdin IX beta reductase (BVR-B, aka flavin reductase)-like proteins; atypical (a) SDRs; Region: BVR-B_like_SDR_a; cd05244
1034836010395	NADH(P)-binding; Region: NAD_binding_10; pfam13460
1034836010396	NAD binding site [chemical binding]; other site
1034836010397	substrate binding site [chemical binding]; other site
1034836010398	putative active site [active]
1034836010399	Predicted transcriptional regulator [Transcription]; Region: COG1959
1034836010400	Transcriptional regulator; Region: Rrf2; pfam02082
1034836010401	urease subunit alpha; Reviewed; Region: ureC; PRK13207
1034836010402	Urease alpha-subunit; Urease is a nickel-dependent metalloenzyme that catalyzes the hydrolysis of urea to form ammonia and carbon dioxide. Nickel-dependent ureases are found in bacteria, fungi and plants. Their primary role is to allow the use of...; Region: Urease_alpha; cd00375
1034836010403	subunit interactions [polypeptide binding]; other site
1034836010404	active site
1034836010405	flap region; other site
1034836010406	Urease beta-subunit; Urease is a nickel-dependent metalloenzyme that catalyzes the hydrolysis of urea to form ammonia and carbon dioxide. Nickel-dependent ureases are found in bacteria, archaea, fungi and plants. Their primary role is to allow the use of...; Region: Urease_beta; cd00407
1034836010407	gamma-beta subunit interface [polypeptide binding]; other site
1034836010408	alpha-beta subunit interface [polypeptide binding]; other site
1034836010409	Urease gamma-subunit; Urease is a nickel-dependent metalloenzyme that catalyzes the hydrolysis of urea to form ammonia and carbon dioxide. Nickel-dependent ureases are found in bacteria, archaea, fungi and plants. Their primary role is to allow the use...; Region: Urease_gamma; cd00390
1034836010410	alpha-gamma subunit interface [polypeptide binding]; other site
1034836010411	beta-gamma subunit interface [polypeptide binding]; other site
1034836010412	CsbD-like; Region: CsbD; pfam05532
1034836010413	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
1034836010414	TPR motif; other site
1034836010415	binding surface
1034836010416	Tetratricopeptide repeat; Region: TPR_12; pfam13424
1034836010417	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1034836010418	binding surface
1034836010419	TPR motif; other site
1034836010420	TPR repeat; Region: TPR_11; pfam13414
1034836010421	molybdenum cofactor biosynthesis protein A; Reviewed; Region: moaA; PRK00164
1034836010422	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1034836010423	FeS/SAM binding site; other site
1034836010424	Molybdenum Cofactor Synthesis C; Region: Mob_synth_C; pfam06463
1034836010425	formate dehydrogenase accessory protein; Reviewed; Region: PRK00724
1034836010426	VWA ywmD type:Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b...; Region: vWA_ywmD_type; cd01456
1034836010427	metal ion-dependent adhesion site (MIDAS); other site
1034836010428	VWA ywmD type:Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b...; Region: vWA_ywmD_type; cd01456
1034836010429	metal ion-dependent adhesion site (MIDAS); other site
1034836010430	Stage II sporulation protein; Region: SpoIID; pfam08486
1034836010431	SpoIID/LytB domain; Region: SpoIID_LytB; TIGR02669
1034836010432	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
1034836010433	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
1034836010434	hinge; other site
1034836010435	active site
1034836010436	Protein of unknown function (DUF1779); Region: DUF1779; pfam08680
1034836010437	Protein of unknown function (DUF1146); Region: DUF1146; cl11486
1034836010438	F0F1 ATP synthase subunit epsilon; Validated; Region: atpC; PRK00571
1034836010439	mitochondrial ATP synthase delta subunit; Region: F1-ATPase_delta; cd12152
1034836010440	gamma subunit interface [polypeptide binding]; other site
1034836010441	epsilon subunit interface [polypeptide binding]; other site
1034836010442	LBP interface [polypeptide binding]; other site
1034836010443	F0F1 ATP synthase subunit beta; Validated; Region: PRK09280
1034836010444	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
1034836010445	F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133
1034836010446	alpha subunit interaction interface [polypeptide binding]; other site
1034836010447	Walker A motif; other site
1034836010448	ATP binding site [chemical binding]; other site
1034836010449	Walker B motif; other site
1034836010450	inhibitor binding site; inhibition site
1034836010451	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
1034836010452	mitochondrial ATP synthase gamma subunit; Region: F1-ATPase_gamma; cd12151
1034836010453	core domain interface [polypeptide binding]; other site
1034836010454	delta subunit interface [polypeptide binding]; other site
1034836010455	epsilon subunit interface [polypeptide binding]; other site
1034836010456	F0F1 ATP synthase subunit alpha; Validated; Region: PRK09281
1034836010457	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
1034836010458	F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to...; Region: F1_ATPase_alpha; cd01132
1034836010459	beta subunit interaction interface [polypeptide binding]; other site
1034836010460	Walker A motif; other site
1034836010461	ATP binding site [chemical binding]; other site
1034836010462	Walker B motif; other site
1034836010463	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
1034836010464	ATP synthase, F1 delta subunit; Region: ATP_synt_delta; TIGR01145
1034836010465	ATP synthase delta (OSCP) subunit; Region: OSCP; pfam00213
1034836010466	F0F1-type ATP synthase, subunit b [Energy production and conversion]; Region: AtpF; COG0711
1034836010467	F0F1 ATP synthase subunit B; Validated; Region: PRK05759
1034836010468	F0F1 ATP synthase subunit C; Validated; Region: PRK06876
1034836010469	F0F1-type ATP synthase, subunit a [Energy production and conversion]; Region: AtpB; COG0356
1034836010470	F0F1 ATP synthase subunit A; Validated; Region: PRK05815
1034836010471	ATP synthase I chain; Region: ATP_synt_I; pfam03899
1034836010472	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1034836010473	active site
1034836010474	serine hydroxymethyltransferase; Reviewed; Region: glyA; PRK00011
1034836010475	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
1034836010476	dimer interface [polypeptide binding]; other site
1034836010477	active site
1034836010478	glycine-pyridoxal phosphate binding site [chemical binding]; other site
1034836010479	folate binding site [chemical binding]; other site
1034836010480	hypothetical protein; Provisional; Region: PRK13690
1034836010481	ribose-5-phosphate isomerase B; Provisional; Region: PRK05571
1034836010482	Low molecular weight phosphatase family; Region: LMWPc; cl00105
1034836010483	Low molecular weight phosphotyrosine protein phosphatase; Region: LMWPc; pfam01451
1034836010484	Predicted membrane protein [Function unknown]; Region: COG1971
1034836010485	Domain of unknown function DUF; Region: DUF204; pfam02659
1034836010486	Domain of unknown function DUF; Region: DUF204; pfam02659
1034836010487	Putative translation factor (SUA5) [Translation, ribosomal structure and biogenesis]; Region: SUA5; COG0009
1034836010488	Putative GTP-binding controlling metal-binding; Region: SUA5; pfam03481
1034836010489	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
1034836010490	stage II sporulation protein R; Region: spore_II_R; TIGR02837
1034836010491	N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional; Region: PRK09328
1034836010492	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1034836010493	S-adenosylmethionine binding site [chemical binding]; other site
1034836010494	peptide chain release factor 1; Validated; Region: prfA; PRK00591
1034836010495	This domain is found in peptide chain release factors; Region: PCRF; smart00937
1034836010496	RF-1 domain; Region: RF-1; pfam00472
1034836010497	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_1; cd08352
1034836010498	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1034836010499	putative metal binding site [ion binding]; other site
1034836010500	polar chromosome segregation protein; Reviewed; Region: racA; PRK13182
1034836010501	Helix-Turn-Helix DNA binding domain of truncated MerR-like proteins; Region: HTH_MerR-trunc; cd04762
1034836010502	DNA binding residues [nucleotide binding]
1034836010503	Trypanosomal VSG domain; Region: VSG_B; cl11958
1034836010504	he Auxin Efflux Carrier (AEC) Family; Region: 2a69; TIGR00946
1034836010505	malate dehydrogenase; Provisional; Region: PRK13529
1034836010506	Malic enzyme, N-terminal domain; Region: malic; pfam00390
1034836010507	NAD(P) binding domain of malic enzyme (ME), subgroup 1; Region: NAD_bind_1_malic_enz; cd05312
1034836010508	NAD(P) binding site [chemical binding]; other site
1034836010509	thymidine kinase; Provisional; Region: PRK04296
1034836010510	50S ribosomal protein L31; Reviewed; Region: rpmE; PRK00019
1034836010511	transcription termination factor Rho; Provisional; Region: rho; PRK09376
1034836010512	Rho termination factor, N-terminal domain; Region: Rho_N; pfam07498
1034836010513	Rho_CSD: Rho protein cold-shock domain (CSD). Rho protein is a transcription termination factor in most bacteria. In bacteria, there are two distinct mechanisms for mRNA transcription termination. In intrinsic termination, RNA polymerase and nascent mRNA...; Region: Rho_CSD; cd04459
1034836010514	RNA binding site [nucleotide binding]; other site
1034836010515	Transcription termination factor rho is a bacterial ATP-dependent RNA/DNA helicase. It is a homohexamer. Each monomer consists of an N-terminal domain of the OB fold, which is responsible for binding to cysteine rich nucleotides. This alignment is of the...; Region: rho_factor; cd01128
1034836010516	multimer interface [polypeptide binding]; other site
1034836010517	Walker A motif; other site
1034836010518	ATP binding site [chemical binding]; other site
1034836010519	Walker B motif; other site
1034836010520	Bacterial fructose-1,6-bisphosphatase, glpX-encoded. A dimeric enzyme dependent on Mg(2+). glpX-encoded FPBase (FBPase class II) differs from other members of the inositol-phosphatase superfamily by permutation of secondary structure elements. The core...; Region: FBPase_glpX; cd01516
1034836010521	Bacterial fructose-1,6-bisphosphatase, glpX-encoded; Region: FBPase_glpX; pfam03320
1034836010522	putative active site [active]
1034836010523	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
1034836010524	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
1034836010525	hinge; other site
1034836010526	active site
1034836010527	Transaldolase-like fructose-6-phosphate aldolases (FSA) found in bacteria and archaea; Region: Transaldolase_FSA; cd00956
1034836010528	active site
1034836010529	intersubunit interactions; other site
1034836010530	catalytic residue [active]
1034836010531	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
1034836010532	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
1034836010533	intersubunit interface [polypeptide binding]; other site
1034836010534	active site
1034836010535	zinc binding site [ion binding]; other site
1034836010536	Na+ binding site [ion binding]; other site
1034836010537	Response regulator receiver domain; Region: Response_reg; pfam00072
1034836010538	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1034836010539	active site
1034836010540	phosphorylation site [posttranslational modification]
1034836010541	intermolecular recognition site; other site
1034836010542	dimerization interface [polypeptide binding]; other site
1034836010543	Protein of unknown function (DUF2529); Region: DUF2529; pfam10740
1034836010544	CTP synthetase; Validated; Region: pyrG; PRK05380
1034836010545	CTP synthetase (CTPs) is a two-domain protein, which consists of an N-terminal synthetase domain and C-terminal glutaminase domain. The enzymes hydrolyze the amide bond of glutamine to ammonia and glutamate at the glutaminase domains and transfer nascent...; Region: CTGs; cd03113
1034836010546	Catalytic site [active]
1034836010547	active site
1034836010548	UTP binding site [chemical binding]; other site
1034836010549	Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; Region: GATase1_CTP_Synthase; cd01746
1034836010550	active site
1034836010551	putative oxyanion hole; other site
1034836010552	catalytic triad [active]
1034836010553	DNA-directed RNA polymerase delta subunit; Region: RNA_pol_delta; pfam05066
1034836010554	Protein of unknown function (DUF4199); Region: DUF4199; pfam13858
1034836010555	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
1034836010556	Cysteine-rich domain; Region: CCG; pfam02754
1034836010557	Cysteine-rich domain; Region: CCG; pfam02754
1034836010558	Catalytic domain, repeat 1, of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_1; cd09110
1034836010559	PLD-like domain; Region: PLDc_2; pfam13091
1034836010560	putative active site [active]
1034836010561	catalytic site [active]
1034836010562	catalytic domain repeat 2 of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_2; cd09112
1034836010563	PLD-like domain; Region: PLDc_2; pfam13091
1034836010564	putative active site [active]
1034836010565	catalytic site [active]
1034836010566	putative UV damage endonuclease; Provisional; Region: uvsE; PRK02308
1034836010567	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1034836010568	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1034836010569	ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; Region: ABCC_MsbA; cd03251
1034836010570	Walker A/P-loop; other site
1034836010571	ATP binding site [chemical binding]; other site
1034836010572	Q-loop/lid; other site
1034836010573	ABC transporter signature motif; other site
1034836010574	Walker B; other site
1034836010575	D-loop; other site
1034836010576	H-loop/switch region; other site
1034836010577	cardiolipin synthetase; Reviewed; Region: cls; PRK01642
1034836010578	Catalytic domain, repeat 1, of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_1; cd09110
1034836010579	putative active site [active]
1034836010580	catalytic site [active]
1034836010581	catalytic domain repeat 2 of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_2; cd09112
1034836010582	putative active site [active]
1034836010583	catalytic site [active]
1034836010584	respiratory nitrate reductase, gamma subunit; Region: narI; TIGR00351
1034836010585	Nitrate reductase delta subunit; Region: Nitrate_red_del; cl00958
1034836010586	Nitrate reductase beta subunit [Energy production and conversion]; Region: NarY; COG1140
1034836010587	respiratory nitrate reductase, alpha subunit; Region: narG; TIGR01580
1034836010588	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_Nitrate-R-NarG-like; cd02750
1034836010589	[4Fe-4S] binding site [ion binding]; other site
1034836010590	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1034836010591	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1034836010592	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1034836010593	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_CT_Nitrate-R-NarG-like; cd02776
1034836010594	molybdopterin cofactor binding site; other site
1034836010595	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cl00047
1034836010596	ligand binding site [chemical binding]; other site
1034836010597	flexible hinge region; other site
1034836010598	YwiC-like protein; Region: YwiC; pfam14256
1034836010599	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
1034836010600	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
1034836010601	ligand binding site [chemical binding]; other site
1034836010602	flexible hinge region; other site
1034836010603	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
1034836010604	putative switch regulator; other site
1034836010605	non-specific DNA interactions [nucleotide binding]; other site
1034836010606	DNA binding site [nucleotide binding]
1034836010607	sequence specific DNA binding site [nucleotide binding]; other site
1034836010608	putative cAMP binding site [chemical binding]; other site
1034836010609	Nitrate/nitrite transporter [Inorganic ion transport and metabolism]; Region: NarK; COG2223
1034836010610	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1034836010611	putative substrate translocation pore; other site
1034836010612	arginyl-tRNA synthetase; Reviewed; Region: argS; PRK01611
1034836010613	Arginyl tRNA synthetase N terminal dom; Region: Arg_tRNA_synt_N; smart01016
1034836010614	catalytic core domain of arginyl-tRNA synthetases; Region: ArgRS_core; cd00671
1034836010615	active site
1034836010616	HIGH motif; other site
1034836010617	KMSK motif region; other site
1034836010618	Anticodon-binding domain of arginyl tRNA synthetases; Region: Anticodon_Ia_Arg; cd07956
1034836010619	tRNA binding surface [nucleotide binding]; other site
1034836010620	anticodon binding site; other site
1034836010621	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4506
1034836010622	Uncharacterized conserved protein [Function unknown]; Region: COG3391
1034836010623	40-residue YVTN family beta-propeller repeat; Region: beta_rpt_yvtn; TIGR02276
1034836010624	Anaphase-promoting complex, cyclosome, subunit 3; Region: Apc3; pfam12895
1034836010625	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1034836010626	binding surface
1034836010627	TPR motif; other site
1034836010628	Tetratricopeptide repeat; Region: TPR_12; pfam13424
1034836010629	Rap-phr extracellular signalling; Region: PhrC_PhrF; pfam11131
1034836010630	agmatinase; Region: agmatinase; TIGR01230
1034836010631	Agmatinase and related proteins; Region: Agmatinase-like_2; cd11593
1034836010632	putative active site [active]
1034836010633	Mn binding site [ion binding]; other site
1034836010634	spermidine synthase; Provisional; Region: PRK00811
1034836010635	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
1034836010636	Membrane carboxypeptidase (penicillin-binding protein) [Cell envelope biogenesis, outer membrane]; Region: MrcB; COG0744
1034836010637	Transglycosylase; Region: Transgly; pfam00912
1034836010638	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
1034836010639	YwhD family; Region: YwhD; pfam08741
1034836010640	Uncharacterized homologs of Site-2 protease (S2P), zinc metalloproteases (MEROPS family M50) which cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of the...; Region: S2P-M50_like_1; cd06158
1034836010641	Peptidase family M50; Region: Peptidase_M50; pfam02163
1034836010642	active site
1034836010643	putative substrate binding region [chemical binding]; other site
1034836010644	4-Oxalocrotonate Tautomerase:  Catalyzes the isomerization of unsaturated ketones. The structure is a homohexamer that is arranged as a trimer of dimers. The hexamer contains six active sites, each formed by residues from three monomers, two from one...; Region: 4Oxalocrotonate_Tautomerase; cd00491
1034836010645	active site 1 [active]
1034836010646	dimer interface [polypeptide binding]; other site
1034836010647	hexamer interface [polypeptide binding]; other site
1034836010648	active site 2 [active]
1034836010649	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1034836010650	dimerization interface [polypeptide binding]; other site
1034836010651	putative DNA binding site [nucleotide binding]; other site
1034836010652	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1034836010653	putative Zn2+ binding site [ion binding]; other site
1034836010654	amino acid transporter; Region: 2A0306; TIGR00909
1034836010655	C-terminus of AA_permease; Region: AA_permease_C; pfam13906
1034836010656	Uncharacterized conserved protein [Function unknown]; Region: COG3465
1034836010657	HD superfamily phosphohydrolases [General function prediction only]; Region: COG1078
1034836010658	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1034836010659	Zn2+ binding site [ion binding]; other site
1034836010660	Mg2+ binding site [ion binding]; other site
1034836010661	Protein of unknown function (DUF1450); Region: DUF1450; cl11488
1034836010662	putative spore coat protein regulator protein YlbO; Provisional; Region: PRK13923
1034836010663	Predicted transcriptional regulators [Transcription]; Region: COG1695
1034836010664	Transcriptional regulator PadR-like family; Region: PadR; pfam03551
1034836010665	Protein of unknown function (DUF1700); Region: DUF1700; pfam08006
1034836010666	potential frameshift: common BLAST hit: gi|154687875|ref|YP_001423036.1| putative ABC transporter ATP-binding protein
1034836010667	ABC-2 family transporter protein; Region: ABC2_membrane_4; pfam12730
1034836010668	ABC-2 family transporter protein; Region: ABC2_membrane_2; cl17866
1034836010669	Lipoate-protein ligase A [Coenzyme metabolism]; Region: LplA; COG0095
1034836010670	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1034836010671	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1034836010672	C-terminal substrate binding domain of LysR-type transcriptional regulator CysL, which activates the transcription of the cysJI operon encoding sulfite reductase, contains the type 2 periplasmic binding fold; Region: PBP2_CysL_like; cd08420
1034836010673	putative dimerization interface [polypeptide binding]; other site
1034836010674	Predicted membrane protein [Function unknown]; Region: COG2855
1034836010675	phosphotransacetylase; Reviewed; Region: eutD; PRK09653
1034836010676	putative heme peroxidase; Provisional; Region: PRK12276
1034836010677	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653
1034836010678	putative beta-ketoacyl acyl carrier protein [ACP] reductase (BKR)-like, SDR; Region: BKR_like_SDR_like; cd05344
1034836010679	putative NAD(P) binding site [chemical binding]; other site
1034836010680	putative active site [active]
1034836010681	transaminase; Reviewed; Region: PRK08068
1034836010682	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1034836010683	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1034836010684	homodimer interface [polypeptide binding]; other site
1034836010685	catalytic residue [active]
1034836010686	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1034836010687	H+ Antiporter protein; Region: 2A0121; TIGR00900
1034836010688	putative substrate translocation pore; other site
1034836010689	Biotin carboxylase [Lipid metabolism]; Region: AccC; COG0439
1034836010690	ATP-grasp domain; Region: ATP-grasp_4; pfam13535
1034836010691	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653
1034836010692	classical (c) SDRs; Region: SDR_c; cd05233
1034836010693	NAD(P) binding site [chemical binding]; other site
1034836010694	active site
1034836010695	Cupin domain; Region: Cupin_2; pfam07883
1034836010696	Cupin domain; Region: Cupin_2; pfam07883
1034836010697	Prephenate dehydratase; Region: PDT; pfam00800
1034836010698	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
1034836010699	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1034836010700	putative substrate translocation pore; other site
1034836010701	drug resistance transporter, Bcr/CflA subfamily; Region: efflux_Bcr_CflA; TIGR00710
1034836010702	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1034836010703	putative substrate translocation pore; other site
1034836010704	S-methylmethionine transporter; Provisional; Region: PRK11387
1034836010705	M20 Peptidase Arginine utilization protein, RocB; Region: M20_ArgE_RocB; cd05654
1034836010706	putative metal binding site [ion binding]; other site
1034836010707	putative dimer interface [polypeptide binding]; other site
1034836010708	1-pyrroline-5-carboxylate dehydrogenase; Provisional; Region: PRK03137
1034836010709	Delta(1)-pyrroline-5-carboxylate dehydrogenase, RocA; Region: ALDH_PutA-P5CDH-RocA; cd07124
1034836010710	Glutamate binding site [chemical binding]; other site
1034836010711	homodimer interface [polypeptide binding]; other site
1034836010712	NAD binding site [chemical binding]; other site
1034836010713	catalytic residues [active]
1034836010714	Glutamate dehydrogenase/leucine dehydrogenase [Amino acid transport and metabolism]; Region: GdhA; COG0334
1034836010715	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
1034836010716	NAD(P) binding domain of glutamate dehydrogenase, subgroup 1; Region: NAD_bind_1_Glu_DH; cd01076
1034836010717	NAD(P) binding site [chemical binding]; other site
1034836010718	dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes [Cell envelope biogenesis, outer membrane]; Region: RfbC; COG1898
1034836010719	dTDP-4-dehydrorhamnose reductase [Cell envelope biogenesis, outer membrane]; Region: RfbD; COG1091
1034836010720	dTDP-6-deoxy-L-lyxo-4-hexulose reductase and related proteins, extended (e) SDRs; Region: dTDP_HR_like_SDR_e; cd05254
1034836010721	NADP binding site [chemical binding]; other site
1034836010722	active site
1034836010723	putative substrate binding site [chemical binding]; other site
1034836010724	dTDP-D-glucose 4,6-dehydratase [Cell envelope biogenesis, outer membrane]; Region: RfbB; COG1088
1034836010725	dTDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: dTDP_GD_SDR_e; cd05246
1034836010726	NAD binding site [chemical binding]; other site
1034836010727	substrate binding site [chemical binding]; other site
1034836010728	homodimer interface [polypeptide binding]; other site
1034836010729	active site
1034836010730	G1P_TT_short is the short form of glucose-1-phosphate thymidylyltransferase; Region: G1P_TT_short; cd02538
1034836010731	dTDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane]; Region: RfbA; COG1209
1034836010732	substrate binding site; other site
1034836010733	tetramer interface; other site
1034836010734	Spore coat polysaccharide biosynthesis protein, predicted glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: spsG; COG3980
1034836010735	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
1034836010736	SpsF is a glycosyltrnasferase implicated in the synthesis of the spore coat; Region: GT2_SpsF; cd02518
1034836010737	ligand binding site; other site
1034836010738	Sialic acid synthase [Cell envelope biogenesis, outer membrane]; Region: SpsE; COG2089
1034836010739	NeuB family; Region: NeuB; pfam03102
1034836010740	C-terminal SAF domain of sialic acid synthetase; Region: SAF_NeuB_like; cd11615
1034836010741	NeuB binding interface [polypeptide binding]; other site
1034836010742	putative substrate binding site [chemical binding]; other site
1034836010743	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1034836010744	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
1034836010745	Coenzyme A binding pocket [chemical binding]; other site
1034836010746	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
1034836010747	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
1034836010748	inhibitor-cofactor binding pocket; inhibition site
1034836010749	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1034836010750	catalytic residue [active]
1034836010751	Putative glycosyl/glycerophosphate transferases involved in teichoic acid biosynthesis TagF/TagB/EpsJ/RodC [Cell envelope biogenesis, outer membrane]; Region: TagB; COG1887
1034836010752	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
1034836010753	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
1034836010754	active site
1034836010755	Spore coat protein (Spore_GerQ); Region: Spore_GerQ; pfam09671
1034836010756	Uncharacterized small membrane protein [Function unknown]; Region: COG2363
1034836010757	Permease family; Region: Xan_ur_permease; pfam00860
1034836010758	Family 1 of Uracil-DNA glycosylase (UDG) enzymes; Region: UDG_F1; cd10027
1034836010759	ligand binding site [chemical binding]; other site
1034836010760	active site
1034836010761	UGI interface [polypeptide binding]; other site
1034836010762	catalytic site [active]
1034836010763	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
1034836010764	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
1034836010765	active site
1034836010766	4-amino-5-hydroxymethyl-2-methyl-pyrimidine phosphate kinase (HMPP-kinase) catalyzes two consecutive phosphorylation steps in the thiamine phosphate biosynthesis pathway, leading to the synthesis of vitamin B1. The first step is the phosphorylation of...; Region: HMPP_kinase; cd01169
1034836010767	dimer interface [polypeptide binding]; other site
1034836010768	substrate binding site [chemical binding]; other site
1034836010769	ATP binding site [chemical binding]; other site
1034836010770	sucrose-6-phosphate hydrolase; Region: scrB_fam; TIGR01322
1034836010771	Glycosyl hydrolase family 32, beta-fructosidases; Region: GH32_B_Fructosidase; cd08996
1034836010772	substrate binding [chemical binding]; other site
1034836010773	active site
1034836010774	Glycosyl hydrolases family 32 C terminal; Region: Glyco_hydro_32C; pfam08244
1034836010775	PTS system, sucrose-specific IIBC component; Region: PTS-II-BC-sucr; TIGR01996
1034836010776	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1034836010777	active site turn [active]
1034836010778	phosphorylation site [posttranslational modification]
1034836010779	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1034836010780	transcriptional antiterminator BglG; Provisional; Region: PRK09772
1034836010781	CAT RNA binding domain; Region: CAT_RBD; smart01061
1034836010782	PRD domain; Region: PRD; pfam00874
1034836010783	PRD domain; Region: PRD; pfam00874
1034836010784	Subtilisin-like serine proteases [Posttranslational modification, protein turnover, chaperones]; Region: AprE; COG1404
1034836010785	Peptidase inhibitor I9; Region: Inhibitor_I9; pfam05922
1034836010786	Peptidase S8 family domain in Vpr-like proteins; Region: Peptidases_S8_subtilisin_Vpr-like; cd07474
1034836010787	putative active site [active]
1034836010788	catalytic triad [active]
1034836010789	PA_C5a_like: Protease-associated domain containing proteins like Streptococcus pyogenes C5a peptidase. This group contains various PA domain-containing proteins similar to S. pyogenes C5a, including, i) Vpr, a minor extracellular serine protease from...; Region: PA_C5a_like; cd02133
1034836010790	PA/protease domain interface [polypeptide binding]; other site
1034836010791	putative integrin binding motif; other site
1034836010792	Peptidase S8 family domain in Vpr-like proteins; Region: Peptidases_S8_subtilisin_Vpr-like; cd07474
1034836010793	FlgD Tudor-like domain; Region: FLgD_tudor; pfam13861
1034836010794	luciferase family oxidoreductase, group 1; Region: oxido_grp_1; TIGR03558
1034836010795	Flavin-utilizing monoxygenases; Region: Flavin_utilizing_monoxygenases; cl07892
1034836010796	Predicted transcriptional regulator [Transcription]; Region: COG2378
1034836010797	HTH domain; Region: HTH_11; pfam08279
1034836010798	WYL domain; Region: WYL; pfam13280
1034836010799	short chain dehydrogenase; Provisional; Region: PRK06523
1034836010800	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1034836010801	NAD(P) binding site [chemical binding]; other site
1034836010802	active site
1034836010803	Calcium/calmodulin dependent protein kinase II Association; Region: CaMKII_AD; cl17504
1034836010804	Stress responsive A/B Barrel Domain; Region: Dabb; smart00886
1034836010805	This family contains NADPH-dependent flavin reductase and oxygen-insensitive nitroreductase. These enzymes are homodimeric flavoproteins that contain one FMN per monomer as a cofactor. Flavin reductase catalyzes the reduction of flavin by using NADPH as...; Region: NfsA_FRP; cd02146
1034836010806	dimer interface [polypeptide binding]; other site
1034836010807	FMN binding site [chemical binding]; other site
1034836010808	NADPH bind site [chemical binding]; other site
1034836010809	Cell cycle protein; Region: FTSW_RODA_SPOVE; pfam01098
1034836010810	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
1034836010811	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1034836010812	Coenzyme A binding pocket [chemical binding]; other site
1034836010813	cytochrome aa3 quinol oxidase, subunit IV; Region: QoxD; TIGR02901
1034836010814	Ubiquinol oxidase subunit III subfamily. Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane.  It catalyzes the reduction of O2 and simultaneously...; Region: Ubiquinol_oxidase_III; cd02863
1034836010815	Subunit I/III interface [polypeptide binding]; other site
1034836010816	Subunit III/IV interface [polypeptide binding]; other site
1034836010817	Heme/copper-type cytochrome/quinol oxidases, subunit 1 [Energy production and conversion]; Region: CyoB; COG0843
1034836010818	Ubiquinol oxidase subunit I.  Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane.  It catalyzes the reduction of O2 and simultaneously pumps protons...; Region: Ubiquinol_Oxidase_I; cd01662
1034836010819	D-pathway; other site
1034836010820	Putative ubiquinol binding site [chemical binding]; other site
1034836010821	Low-spin heme (heme b) binding site [chemical binding]; other site
1034836010822	Putative water exit pathway; other site
1034836010823	Binuclear center (heme o3/CuB) [ion binding]; other site
1034836010824	K-pathway; other site
1034836010825	Putative proton exit pathway; other site
1034836010826	cytochrome aa3 quinol oxidase, subunit II; Region: QOXA; TIGR01432
1034836010827	Cytochrome C oxidase subunit II, transmembrane domain; Region: COX2_TM; pfam02790
1034836010828	COX Aromatic Rich Motif; Region: COX_ARM; pfam06481
1034836010829	galactose-1-phosphate uridylyltransferase; Provisional; Region: PRK05270
1034836010830	Galactose-1-phosphate uridyl transferase, N-terminal domain; Region: GalP_UDP_transf; pfam01087
1034836010831	Galactose-1-phosphate uridyl transferase, C-terminal domain; Region: GalP_UDP_tr_C; pfam02744
1034836010832	galactokinase; Provisional; Region: PRK05322
1034836010833	Galactokinase galactose-binding signature; Region: GalKase_gal_bdg; pfam10509
1034836010834	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
1034836010835	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
1034836010836	Predicted membrane protein [Function unknown]; Region: COG2246
1034836010837	GtrA-like protein; Region: GtrA; pfam04138
1034836010838	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1034836010839	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1034836010840	Uso1 / p115 like vesicle tethering protein, head region; Region: Uso1_p115_head; pfam04869
1034836010841	Anti-repressor SinI; Region: SinI; pfam08671
1034836010842	Methyltransferase domain; Region: Methyltransf_23; pfam13489
1034836010843	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1034836010844	S-adenosylmethionine binding site [chemical binding]; other site
1034836010845	Glycosyltransferase like family; Region: Glyco_tranf_2_5; pfam13712
1034836010846	Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]; Region: FrnE; COG2761
1034836010847	DsbA family, FrnE subfamily; FrnE is a DsbA-like protein containing a CXXC motif. It is presumed to be a thiol oxidoreductase involved in polyketide biosynthesis, specifically in the production of the aromatic antibiotics frenolicin and nanaomycins; Region: DsbA_FrnE; cd03024
1034836010848	catalytic residues [active]
1034836010849	Tat-translocated enzyme; Region: tat_substr_1; TIGR01412
1034836010850	Predicted iron-dependent peroxidase [Inorganic ion transport and metabolism]; Region: COG2837
1034836010851	Predicted periplasmic lipoprotein involved in iron transport [Inorganic ion transport and metabolism]; Region: COG2822
1034836010852	Imelysin; Region: Peptidase_M75; pfam09375
1034836010853	FTR1 family protein; Region: TIGR00145
1034836010854	Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-; Region: TMP_TenI; cd00564
1034836010855	thiamine phosphate binding site [chemical binding]; other site
1034836010856	active site
1034836010857	pyrophosphate binding site [ion binding]; other site
1034836010858	4-methyl-5-beta-hydroxyethylthiazole (Thz) kinase catalyzes the phosphorylation of the hydroxylgroup of Thz. A reaction that allows cells to recycle Thz into the thiamine biosynthesis pathway, as an alternative to its synthesis from cysteine, tyrosine...; Region: THZ_kinase; cd01170
1034836010859	substrate binding site [chemical binding]; other site
1034836010860	multimerization interface [polypeptide binding]; other site
1034836010861	ATP binding site [chemical binding]; other site
1034836010862	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1034836010863	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1034836010864	The C-terminal substrate binding domain of LysR-like transcriptional regulator CidR, contains the type 2 periplasmic binding fold; Region: PBP2_CidR; cd08438
1034836010865	putative dimerization interface [polypeptide binding]; other site
1034836010866	LrgA family; Region: LrgA; cl00608
1034836010867	LrgB-like family; Region: LrgB; cl00596
1034836010868	Uncharacterized conserved protein (DUF2196); Region: DUF2196; pfam09962
1034836010869	Helix-Turn-Helix DNA binding domain of the transcription regulators TipAL, Mta, and SkgA; Region: HTH_TipAL-Mta; cd01106
1034836010870	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
1034836010871	DNA binding residues [nucleotide binding]
1034836010872	dimer interface [polypeptide binding]; other site
1034836010873	TipAS antibiotic-recognition domain; Region: TipAS; pfam07739
1034836010874	Predicted Zn-dependent protease [Posttranslational modification, protein turnover, chaperones]; Region: COG5504
1034836010875	Predicted SAM-dependent methyltransferases [General function prediction only]; Region: COG1092
1034836010876	Middle domain of the SAM-dependent methyltransferase RlmI and related proteins; Region: RlmI_M_like; cd11572
1034836010877	putative RNA binding site [nucleotide binding]; other site
1034836010878	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1034836010879	S-adenosylmethionine binding site [chemical binding]; other site
1034836010880	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1034836010881	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cd06587
1034836010882	active site
1034836010883	metal binding site [ion binding]; metal-binding site
1034836010884	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
1034836010885	PTS system, lactose/cellobiose family IIC component; Region: lacE; TIGR00410
1034836010886	Peptidase inhibitor I9; Region: Inhibitor_I9; pfam05922
1034836010887	Peptidase S8 family domain in Subtilisin proteins; Region: Peptidases_S8_Subtilisin_subset; cd07477
1034836010888	active site
1034836010889	catalytic residues [active]
1034836010890	A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; Region: GT8_A4GalT_like; cd04194
1034836010891	Glycosyl transferase family 8; Region: Glyco_transf_8; pfam01501
1034836010892	Ligand binding site; other site
1034836010893	metal-binding site
1034836010894	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
1034836010895	synthetase active site [active]
1034836010896	NTP binding site [chemical binding]; other site
1034836010897	metal binding site [ion binding]; metal-binding site
1034836010898	1,4-dihydroxy-2-naphthoate octaprenyltransferase; Validated; Region: PRK06080
1034836010899	UbiA prenyltransferase family; Region: UbiA; pfam01040
1034836010900	D-Ala-teichoic acid biosynthesis protein; Region: DUF3687; pfam12459
1034836010901	D-alanine--poly(phosphoribitol) ligase subunit 1; Provisional; Region: PRK04813
1034836010902	D-alanine:D-alanyl carrier protein ligase (DltA); Region: DltA; cd05945
1034836010903	acyl-activating enzyme (AAE) consensus motif; other site
1034836010904	AMP binding site [chemical binding]; other site
1034836010905	D-alanyl-lipoteichoic acid biosynthesis protein DltB; Region: LTA_dltB; TIGR04091
1034836010906	D-alanine--poly(phosphoribitol) ligase subunit 2; Validated; Region: PRK05087
1034836010907	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein) [Cell envelope biogenesis, outer membrane]; Region: DltD; COG3966
1034836010908	DltD N-terminal region; Region: DltD_N; pfam04915
1034836010909	DltD central region; Region: DltD_M; pfam04918
1034836010910	DltD C-terminal region; Region: DltD_C; pfam04914
1034836010911	branched-chain amino acid aminotransferase; Provisional; Region: PRK13357
1034836010912	BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids  leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and...; Region: BCAT_beta_family; cd01557
1034836010913	homodimer interface [polypeptide binding]; other site
1034836010914	substrate-cofactor binding pocket; other site
1034836010915	catalytic residue [active]
1034836010916	Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: CelF; COG1486
1034836010917	Glycoside Hydrolases Family 4; Phospho-beta-glucosidase; Region: GH4_P_beta_glucosidase; cd05296
1034836010918	NAD binding site [chemical binding]; other site
1034836010919	sugar binding site [chemical binding]; other site
1034836010920	divalent metal binding site [ion binding]; other site
1034836010921	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1034836010922	dimer interface [polypeptide binding]; other site
1034836010923	PTS_IIA, PTS system, lactose/cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_lac; cd00215
1034836010924	methionine cluster; other site
1034836010925	active site
1034836010926	phosphorylation site [posttranslational modification]
1034836010927	metal binding site [ion binding]; metal-binding site
1034836010928	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
1034836010929	PTS system, lactose/cellobiose family IIC component; Region: lacE; TIGR00410
1034836010930	PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N; Region: PTS_IIB_chitobiose_lichenan; cd05564
1034836010931	active site
1034836010932	P-loop; other site
1034836010933	phosphorylation site [posttranslational modification]
1034836010934	Transcriptional antiterminator [Transcription]; Region: BglG; COG3711
1034836010935	HTH domain; Region: HTH_11; pfam08279
1034836010936	Mga helix-turn-helix domain; Region: Mga; pfam05043
1034836010937	PRD domain; Region: PRD; pfam00874
1034836010938	PRD domain; Region: PRD; pfam00874
1034836010939	PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568
1034836010940	active site
1034836010941	P-loop; other site
1034836010942	phosphorylation site [posttranslational modification]
1034836010943	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1034836010944	active site
1034836010945	phosphorylation site [posttranslational modification]
1034836010946	Alkyladenine DNA glycosylase catalyzes the first step in base excision repair; Region: AAG; cd00540
1034836010947	active site
1034836010948	DNA binding site [nucleotide binding]
1034836010949	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
1034836010950	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1034836010951	ABC-ATPase subunit  interface; other site
1034836010952	dimer interface [polypeptide binding]; other site
1034836010953	putative PBP binding regions; other site
1034836010954	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
1034836010955	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1034836010956	ABC-ATPase subunit  interface; other site
1034836010957	dimer interface [polypeptide binding]; other site
1034836010958	putative PBP binding regions; other site
1034836010959	ABC-type Fe3+-hydroxamate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: FepB; COG0614
1034836010960	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
1034836010961	intersubunit interface [polypeptide binding]; other site
1034836010962	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1034836010963	dimerization interface [polypeptide binding]; other site
1034836010964	putative DNA binding site [nucleotide binding]; other site
1034836010965	putative Zn2+ binding site [ion binding]; other site
1034836010966	arsenical pump membrane protein; Provisional; Region: PRK15445
1034836010967	Anion permease ArsB.  These permeases have been shown to export arsenate and antimonite in eubacteria and archaea.  A typical ArsB permease contains 8-13 transmembrane helices and can function either independently as a chemiosmotic transporter or as a...; Region: ArsB_permease; cd01118
1034836010968	transmembrane helices; other site
1034836010969	PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N; Region: PTS_IIB_chitobiose_lichenan; cd05564
1034836010970	active site
1034836010971	P-loop; other site
1034836010972	phosphorylation site [posttranslational modification]
1034836010973	PTS_IIA, PTS system, lactose/cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_lac; cd00215
1034836010974	active site
1034836010975	methionine cluster; other site
1034836010976	phosphorylation site [posttranslational modification]
1034836010977	metal binding site [ion binding]; metal-binding site
1034836010978	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
1034836010979	PTS system, lactose/cellobiose family IIC component; Region: lacE; TIGR00410
1034836010980	Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase [Carbohydrate transport and metabolism]; Region: BglB; COG2723
1034836010981	beta-galactosidase; Region: BGL; TIGR03356
1034836010982	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
1034836010983	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1034836010984	nucleotide binding site [chemical binding]; other site
1034836010985	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
1034836010986	Phosphomannose isomerase [Carbohydrate transport and metabolism]; Region: ManA; COG1482
1034836010987	mannose-6-phosphate isomerase, class I; Region: manA; TIGR00218
1034836010988	Glycosyl hydrolase family 26; Region: Glyco_hydro_26; pfam02156
1034836010989	Catalase [Inorganic ion transport and metabolism]; Region: KatE; COG0753
1034836010990	Clade 1 of the heme-binding enzyme catalase; Region: catalase_clade_1; cd08154
1034836010991	tetramer interface [polypeptide binding]; other site
1034836010992	heme binding pocket [chemical binding]; other site
1034836010993	Linear amide C-N hydrolases, choloylglycine hydrolase family; Region: CBAH; pfam02275
1034836010994	Penicillin V acylase (PVA), also known as conjugated bile salt acid hydrolase (CBAH), catalyzes the hydrolysis of penicillin V to yield 6-amino penicillanic acid (6-APA), an important key intermediate of semisynthetic penicillins.  PVA has an N-terminal...; Region: Ntn_PVA; cd00542
1034836010995	active site
1034836010996	Purine-cytosine permease and related proteins [Nucleotide transport and metabolism]; Region: CodB; COG1457
1034836010997	Permease for cytosine/purines, uracil, thiamine, allantoin; Region: Transp_cyt_pur; pfam02133
1034836010998	Na binding site [ion binding]; other site
1034836010999	B.subtilis YXKO protein of unknown function and related proteins. Based on the conservation of the ATP binding site, the substrate binding site and the Mg2+binding site and structural homology this group is a member of the ribokinase-like superfamily; Region: YXKO-related; cd01171
1034836011000	putative substrate binding site [chemical binding]; other site
1034836011001	putative ATP binding site [chemical binding]; other site
1034836011002	ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion / Posttranslational modification, protein turnover, chaperones]; Region: CydC; COG4987
1034836011003	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1034836011004	ATP-binding cassette domain of CydCD, subfamily C; Region: ABCC_cytochrome_bd; cd03247
1034836011005	Walker A/P-loop; other site
1034836011006	ATP binding site [chemical binding]; other site
1034836011007	Q-loop/lid; other site
1034836011008	ABC transporter signature motif; other site
1034836011009	Walker B; other site
1034836011010	D-loop; other site
1034836011011	H-loop/switch region; other site
1034836011012	ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion / Posttranslational modification, protein turnover, chaperones]; Region: CydD; COG4988
1034836011013	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1034836011014	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1034836011015	ATP binding site [chemical binding]; other site
1034836011016	Q-loop/lid; other site
1034836011017	ABC transporter signature motif; other site
1034836011018	Walker B; other site
1034836011019	D-loop; other site
1034836011020	H-loop/switch region; other site
1034836011021	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003; cl12219
1034836011022	Cytochrome oxidase subunit II; Region: Cyto_ox_2; pfam02322
1034836011023	cytochrome d terminal oxidase subunit 1; Provisional; Region: PRK15097
1034836011024	Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; pfam01654
1034836011025	2-hydroxycarboxylate transporter family; Region: 2HCT; pfam03390
1034836011026	Predicted xylanase/chitin deacetylase [Carbohydrate transport and metabolism]; Region: CDA1; COG0726
1034836011027	Putative catalytic NodB homology domain of PgaB, IcaB, and similar proteins which consist of a deformed (beta/alpha)8 barrel fold with 5- or 6-strands; Region: CE4_NodB_like_5s_6s; cd10918
1034836011028	putative active site [active]
1034836011029	putative metal binding site [ion binding]; other site
1034836011030	glycerol-3-phosphate transporter ATP-binding subunit; Provisional; Region: ugpC; PRK11650
1034836011031	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
1034836011032	Walker A/P-loop; other site
1034836011033	ATP binding site [chemical binding]; other site
1034836011034	Q-loop/lid; other site
1034836011035	ABC transporter signature motif; other site
1034836011036	Walker B; other site
1034836011037	D-loop; other site
1034836011038	H-loop/switch region; other site
1034836011039	TOBE domain; Region: TOBE; pfam03459
1034836011040	Regulator of polyketide synthase expression [Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG2508
1034836011041	PucR C-terminal helix-turn-helix domain; Region: HTH_30; pfam13556
1034836011042	Uncharacterized conserved protein [Function unknown]; Region: COG1284
1034836011043	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
1034836011044	Uncharacterized protein conserved in bacteria (DUF2179); Region: DUF2179; pfam10035
1034836011045	zinc-ribbon domain; Region: zinc_ribbon_2; pfam13240
1034836011046	Domain of unknown function (DUF4352); Region: DUF4352; pfam11611
1034836011047	UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs; Region: UDP_G4E_1_SDR_e; cd05247
1034836011048	UDP-glucose 4-epimerase; Region: PLN02240
1034836011049	NAD binding site [chemical binding]; other site
1034836011050	homodimer interface [polypeptide binding]; other site
1034836011051	active site
1034836011052	substrate binding site [chemical binding]; other site
1034836011053	peptidase T; Region: peptidase-T; TIGR01882
1034836011054	M20 Peptidase T specifically cleaves tripeptides; Region: M20_peptT; cd03892
1034836011055	metal binding site [ion binding]; metal-binding site
1034836011056	dimer interface [polypeptide binding]; other site
1034836011057	Tubby C 2; Region: Tub_2; cl02043
1034836011058	CIMS - Cobalamine-independent methonine synthase, or MetE, C-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_C_terminal_like; cd03311
1034836011059	substrate binding site [chemical binding]; other site
1034836011060	THF binding site; other site
1034836011061	zinc-binding site [ion binding]; other site
1034836011062	23S rRNA methyltransferase A; Provisional; Region: rrmA; PRK11088
1034836011063	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1034836011064	S-adenosylmethionine binding site [chemical binding]; other site
1034836011065	nucleoside transporter; Region: nupC; TIGR00804
1034836011066	Na+ dependent nucleoside transporter N-terminus; Region: Nucleos_tra2_N; pfam01773
1034836011067	Na+ dependent nucleoside transporter C-terminus; Region: Nucleos_tra2_C; pfam07662
1034836011068	Domain of unknown function (DUF4163); Region: DUF4163; pfam13739
1034836011069	Protein of unknown function (DUF3298); Region: DUF3298; pfam11738
1034836011070	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1034836011071	ABC transporter signature motif; other site
1034836011072	Walker B; other site
1034836011073	D-loop; other site
1034836011074	H-loop/switch region; other site
1034836011075	hydroperoxidase II; Provisional; Region: katE; PRK11249
1034836011076	Clade 2 of the heme-binding enzyme catalase; Region: catalase_clade_2; cd08155
1034836011077	tetramer interface [polypeptide binding]; other site
1034836011078	heme binding pocket [chemical binding]; other site
1034836011079	Type 1 glutamine amidotransferase (GATase1)-like domain found in at the C-terminal of several large catalases; Region: GATase1_catalase; cd03132
1034836011080	domain interactions; other site
1034836011081	citrate transporter, CitMHS family; Region: citMHS; TIGR00784
1034836011082	Citrate transporter; Region: CitMHS; pfam03600
1034836011083	Beta-glucanase/Beta-glucan synthetase [Carbohydrate transport and metabolism]; Region: SKN1; COG2273
1034836011084	lichenase, member of glycosyl hydrolase family 16; Region: GH16_lichenase; cd02175
1034836011085	active site
1034836011086	active site
1034836011087	catalytic residues [active]
1034836011088	transcriptional antiterminator BglG; Provisional; Region: PRK09772
1034836011089	CAT RNA binding domain; Region: CAT_RBD; smart01061
1034836011090	PRD domain; Region: PRD; pfam00874
1034836011091	PRD domain; Region: PRD; pfam00874
1034836011092	Permeases of the major facilitator superfamily [General function prediction only]; Region: COG2270
1034836011093	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1034836011094	putative substrate translocation pore; other site
1034836011095	Superfamily II DNA and RNA helicases [DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis]; Region: SrmB; COG0513
1034836011096	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
1034836011097	ATP binding site [chemical binding]; other site
1034836011098	Mg++ binding site [ion binding]; other site
1034836011099	motif III; other site
1034836011100	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1034836011101	nucleotide binding region [chemical binding]; other site
1034836011102	RNA recognition motif in Bacillus subtilis ATP-dependent RNA helicase YxiN and similar proteins; Region: RRM_BsYxiN_like; cd12500
1034836011103	RNA binding site [nucleotide binding]; other site
1034836011104	YxiJ-like protein; Region: YxiJ; pfam14176
1034836011105	Pectate lyase [Carbohydrate transport and metabolism]; Region: PelB; COG3866
1034836011106	Amb_all domain; Region: Amb_all; smart00656
1034836011107	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
1034836011108	EamA-like transporter family; Region: EamA; pfam00892
1034836011109	EamA-like transporter family; Region: EamA; pfam00892
1034836011110	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1034836011111	Ligand Binding Site [chemical binding]; other site
1034836011112	Glycosyl hydrolase family 1; Region: Glyco_hydro_1; cl01046
1034836011113	beta-galactosidase; Region: BGL; TIGR03356
1034836011114	PTS system, beta-glucoside-specific IIABC component; Region: PTS-II-ABC-beta; TIGR01995
1034836011115	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1034836011116	active site turn [active]
1034836011117	phosphorylation site [posttranslational modification]
1034836011118	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1034836011119	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210
1034836011120	HPr interaction site; other site
1034836011121	glycerol kinase (GK) interaction site [polypeptide binding]; other site
1034836011122	active site
1034836011123	phosphorylation site [posttranslational modification]
1034836011124	Superfamily of nucleases including Short Patch Repair (Vsr) Endonucleases, archaeal Holliday junction resolvases, MutH methy-directed DNA mismatch-repair endonucleases, and catalytic domains of many restriction endonucleases, such as EcoRI, BamHI, and...; Region: Restriction_endonuclease_like; cl00277
1034836011125	putative active site [active]
1034836011126	Site-specific DNA methylase [DNA replication, recombination, and repair]; Region: Dcm; COG0270
1034836011127	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
1034836011128	cofactor binding site; other site
1034836011129	DNA binding site [nucleotide binding]
1034836011130	substrate interaction site [chemical binding]; other site
1034836011131	Site-specific DNA methylase [DNA replication, recombination, and repair]; Region: Dcm; COG0270
1034836011132	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
1034836011133	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
1034836011134	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1034836011135	ATP binding site [chemical binding]; other site
1034836011136	G-X-G motif; other site
1034836011137	Z1 domain; Region: Z1; pfam10593
1034836011138	Domain of unknown function (DUF4420); Region: DUF4420; pfam14390
1034836011139	potential frameshift: common BLAST hit: gi|308175646|ref|YP_003922351.1| AIPR protein
1034836011140	Beta-xylosidase [Carbohydrate transport and metabolism]; Region: XynB; COG3507
1034836011141	Glycosyl hydrolase family 43; Region: GH43_ABN_1; cd08998
1034836011142	substrate binding site [chemical binding]; other site
1034836011143	active site
1034836011144	anti-terminator HutP; Provisional; Region: hutP; PRK03065
1034836011145	RNA binding site [nucleotide binding]; other site
1034836011146	hexamer interface [polypeptide binding]; other site
1034836011147	Histidine-zinc binding site [chemical binding]; other site
1034836011148	Phenylalanine ammonia-lyase (PAL) and histidine ammonia-lyase (HAL); Region: PAL-HAL; cd00332
1034836011149	active sites [active]
1034836011150	tetramer interface [polypeptide binding]; other site
1034836011151	urocanate hydratase; Provisional; Region: PRK05414
1034836011152	imidazolonepropionase; Validated; Region: PRK09356
1034836011153	Imidazolonepropionase/imidazolone-5-propionate hydrolase (Imidazolone-5PH) catalyzes the third step in the histidine degradation pathway, the hydrolysis of (S)-3-(5-oxo-4,5-dihydro-3H-imidazol-4-yl)propanoate to N-formimidoyl-L-glutamate. In bacteria; Region: Imidazolone-5PH; cd01296
1034836011154	active site
1034836011155	Agmatinase-like family; Region: Agmatinase-like; cd09990
1034836011156	agmatinase; Region: agmatinase; TIGR01230
1034836011157	active site
1034836011158	oligomer interface [polypeptide binding]; other site
1034836011159	Mn binding site [ion binding]; other site
1034836011160	S-methylmethionine transporter; Provisional; Region: PRK11387
1034836011161	pyrimidine-nucleoside phosphorylase; Reviewed; Region: PRK06078
1034836011162	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
1034836011163	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
1034836011164	Pyrimidine nucleoside phosphorylase C-terminal domain; Region: PYNP_C; pfam07831
1034836011165	Nucleoside permease [Nucleotide transport and metabolism]; Region: NupC; COG1972
1034836011166	Na+ dependent nucleoside transporter N-terminus; Region: Nucleos_tra2_N; pfam01773
1034836011167	Nucleoside recognition; Region: Gate; pfam07670
1034836011168	Na+ dependent nucleoside transporter C-terminus; Region: Nucleos_tra2_C; pfam07662
1034836011169	2-deoxyribose-5-phosphate aldolase (DERA) of the DeoC family; Region: DeoC; cd00959
1034836011170	intersubunit interface [polypeptide binding]; other site
1034836011171	active site
1034836011172	catalytic residue [active]
1034836011173	Transcriptional regulator, contains sigma factor-related N-terminal domain [Transcription]; Region: DeoR; COG2390
1034836011174	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
1034836011175	non-specific DNA interactions [nucleotide binding]; other site
1034836011176	DNA binding site [nucleotide binding]
1034836011177	sequence specific DNA binding site [nucleotide binding]; other site
1034836011178	putative cAMP binding site [chemical binding]; other site
1034836011179	Putative sugar-binding domain; Region: Sugar-bind; pfam04198
1034836011180	sugar phosphate phosphatase; Provisional; Region: PRK10513
1034836011181	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1034836011182	active site
1034836011183	motif I; other site
1034836011184	motif II; other site
1034836011185	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1034836011186	Protein of unknown function (DUF3255); Region: DUF3255; pfam11631
1034836011187	ABC-type Fe3+-hydroxamate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: FepB; COG0614
1034836011188	Periplasmic binding protein FeuA.  These proteins have predicted to function as initial receptors in ABC transport of metal ions in some eubacterial species.  They belong to the TroA superfamily of periplasmic metal binding proteins that share a distinct...; Region: FeuA; cd01138
1034836011189	putative ligand binding residues [chemical binding]; other site
1034836011190	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5294
1034836011191	FtsX-like permease family; Region: FtsX; pfam02687
1034836011192	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1034836011193	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1034836011194	Walker A/P-loop; other site
1034836011195	ATP binding site [chemical binding]; other site
1034836011196	Q-loop/lid; other site
1034836011197	ABC transporter signature motif; other site
1034836011198	Walker B; other site
1034836011199	D-loop; other site
1034836011200	H-loop/switch region; other site
1034836011201	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1034836011202	His Kinase A (phosphoacceptor) domain; Region: HisKA; smart00388
1034836011203	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1034836011204	ATP binding site [chemical binding]; other site
1034836011205	Mg2+ binding site [ion binding]; other site
1034836011206	G-X-G motif; other site
1034836011207	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1034836011208	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1034836011209	active site
1034836011210	phosphorylation site [posttranslational modification]
1034836011211	intermolecular recognition site; other site
1034836011212	dimerization interface [polypeptide binding]; other site
1034836011213	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1034836011214	DNA binding site [nucleotide binding]
1034836011215	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
1034836011216	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
1034836011217	intersubunit interface [polypeptide binding]; other site
1034836011218	active site
1034836011219	zinc binding site [ion binding]; other site
1034836011220	Na+ binding site [ion binding]; other site
1034836011221	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
1034836011222	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cl12060
1034836011223	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
1034836011224	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cl12060
1034836011225	DNA interaction; other site
1034836011226	Metal-binding active site; metal-binding site
1034836011227	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1034836011228	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1034836011229	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1034836011230	Glucuronate isomerase; Region: UxaC; cl00829
1034836011231	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1034836011232	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1034836011233	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1034836011234	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
1034836011235	Acetolactate synthase [Amino acid transport and metabolism]; Region: COG3962
1034836011236	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
1034836011237	PYR/PP interface [polypeptide binding]; other site
1034836011238	dimer interface [polypeptide binding]; other site
1034836011239	TPP binding site [chemical binding]; other site
1034836011240	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1034836011241	Thiamine pyrophosphate (TPP) family, IolD subfamily, TPP-binding module; composed of proteins similar to Rhizobium leguminosarum bv. viciae IolD. IolD plays an important role in myo-inositol catabolism; Region: TPP_IolD; cd02003
1034836011242	TPP-binding site; other site
1034836011243	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1034836011244	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
1034836011245	substrate binding site [chemical binding]; other site
1034836011246	ATP binding site [chemical binding]; other site
1034836011247	Uncharacterized enzyme involved in inositol metabolism [Carbohydrate transport and metabolism]; Region: IolB; COG3718
1034836011248	Methylmalonate semialdehyde dehydrogenase and ALDH family members 6A1 and 6B2; Region: ALDH_F6_MMSDH; cd07085
1034836011249	methylmalonic acid semialdehyde dehydrogenase; Region: MMSDH; TIGR01722
1034836011250	tetrameric interface [polypeptide binding]; other site
1034836011251	NAD binding site [chemical binding]; other site
1034836011252	catalytic residues [active]
1034836011253	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1034836011254	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
1034836011255	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1034836011256	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1034836011257	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1034836011258	active site
1034836011259	catalytic tetrad [active]
1034836011260	Sugar (and other) transporter; Region: Sugar_tr; pfam00083
1034836011261	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1034836011262	putative substrate translocation pore; other site
1034836011263	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1034836011264	heat shock protein 90; Provisional; Region: PRK05218
1034836011265	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1034836011266	ATP binding site [chemical binding]; other site
1034836011267	Mg2+ binding site [ion binding]; other site
1034836011268	G-X-G motif; other site
1034836011269	short chain dehydrogenase; Validated; Region: PRK08589
1034836011270	classical (c) SDRs; Region: SDR_c; cd05233
1034836011271	NAD(P) binding site [chemical binding]; other site
1034836011272	active site
1034836011273	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1034836011274	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1034836011275	active site
1034836011276	phosphorylation site [posttranslational modification]
1034836011277	intermolecular recognition site; other site
1034836011278	dimerization interface [polypeptide binding]; other site
1034836011279	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1034836011280	DNA binding residues [nucleotide binding]
1034836011281	dimerization interface [polypeptide binding]; other site
1034836011282	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG4585
1034836011283	Histidine kinase; Region: HisKA_3; pfam07730
1034836011284	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Region: HATPase_c; pfam02518
1034836011285	ATP binding site [chemical binding]; other site
1034836011286	Mg2+ binding site [ion binding]; other site
1034836011287	G-X-G motif; other site
1034836011288	Fatty acid desaturase [Lipid metabolism]; Region: DesA; COG3239
1034836011289	The Delta12 Fatty Acid Desaturase (Delta12-FADS)-like CD includes the integral-membrane enzymes, delta-12 acyl-lipid desaturases, oleate 12-hydroxylases, omega3 and omega6 fatty acid desaturases, and other related proteins, found in a wide range of...; Region: Delta12-FADS-like; cd03507
1034836011290	putative di-iron ligands [ion binding]; other site
1034836011291	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1034836011292	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1034836011293	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1034836011294	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1034836011295	NAD-dependent aldehyde dehydrogenases [Energy production and conversion]; Region: PutA; COG1012
1034836011296	Pseudomonas putida Aldehyde dehydrogenase AlkH-like; Region: ALDH_AlkH-like; cd07134
1034836011297	NAD(P) binding site [chemical binding]; other site
1034836011298	catalytic residues [active]
1034836011299	FOG: WD40-like repeat [Function unknown]; Region: COG1520
1034836011300	PQQ-dependent dehydrogenases and related proteins; Region: PQQ_DH_like; cl11493
1034836011301	Trp docking motif [polypeptide binding]; other site
1034836011302	active site
1034836011303	The membrane fatty acid desaturase (Membrane_FADS)-like CD includes membrane FADSs, alkane hydroxylases, beta carotene ketolases (CrtW-like), hydroxylases (CrtR-like), and other related proteins. They are present in all groups of organisms with the...; Region: Membrane-FADS-like; cl00615
1034836011304	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1034836011305	putative DNA binding site [nucleotide binding]; other site
1034836011306	dimerization interface [polypeptide binding]; other site
1034836011307	putative Zn2+ binding site [ion binding]; other site
1034836011308	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
1034836011309	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1034836011310	putative substrate translocation pore; other site
1034836011311	RDD family; Region: RDD; pfam06271
1034836011312	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1034836011313	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cd06587
1034836011314	active site
1034836011315	peroxiredoxin; Region: AhpC; TIGR03137
1034836011316	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
1034836011317	dimer interface [polypeptide binding]; other site
1034836011318	decamer (pentamer of dimers) interface [polypeptide binding]; other site
1034836011319	catalytic triad [active]
1034836011320	peroxidatic and resolving cysteines [active]
1034836011321	alkyl hydroperoxide reductase subunit F; Provisional; Region: PRK15317
1034836011322	Alkyl hydroperoxide reductase F subunit (AhpF) N-terminal domain (NTD) family, N-terminal TRX-fold subdomain; AhpF is a homodimeric flavoenzyme which catalyzes the NADH-dependent reduction of the peroxiredoxin AhpC, which in turn catalyzes the reduction...; Region: AhpF_NTD_N; cd02974
1034836011323	catalytic residue [active]
1034836011324	TRX-GRX-like family, Alkyl hydroperoxide reductase F subunit (AhpF) N-terminal domain (NTD) subfamily, C-terminal TRX-fold subdomain; AhpF is a homodimeric flavoenzyme which catalyzes the NADH-dependent reduction of the peroxiredoxin AhpC, which then...; Region: AhpF_NTD_C; cd03026
1034836011325	catalytic residues [active]
1034836011326	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1034836011327	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1034836011328	Major royal jelly protein; Region: MRJP; pfam03022
1034836011329	Gamma-aminobutyrate permease and related permeases [Amino acid transport and metabolism]; Region: AnsP; COG1113
1034836011330	HTH domain; Region: HTH_11; pfam08279
1034836011331	WYL domain; Region: WYL; pfam13280
1034836011332	Bacterial transcription activator, effector binding domain; Region: AraC_E_bind; smart00871
1034836011333	Firmicute fructose-1,6-bisphosphatase; Region: FBPase_2; pfam06874
1034836011334	Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs [Energy production and conversion]; Region: CoxS; COG2080
1034836011335	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
1034836011336	[2Fe-2S] binding domain; Region: Fer2_2; pfam01799
1034836011337	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs [Energy production and conversion]; Region: CoxM; COG1319
1034836011338	CO dehydrogenase flavoprotein C-terminal domain; Region: CO_deh_flav_C; smart01092
1034836011339	Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs [Energy production and conversion]; Region: CoxL; COG1529
1034836011340	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Region: Ald_Xan_dh_C; smart01008
1034836011341	Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738
1034836011342	molybdopterin-guanine dinucleotide biosynthesis protein MobA; Reviewed; Region: mobA; PRK00317
1034836011343	GT_2_like_f is a subfamily of the glycosyltransferase family 2 (GT-2) with unknown function; Region: GT_2_like_f; cd04182
1034836011344	Ligand binding site; other site
1034836011345	metal-binding site
1034836011346	Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family [Posttranslational modification, protein turnover, chaperones]; Region: XdhC; COG1975
1034836011347	XdhC and CoxI family; Region: XdhC_CoxI; pfam02625
1034836011348	XdhC Rossmann domain; Region: XdhC_C; pfam13478
1034836011349	Predicted membrane protein [Function unknown]; Region: COG4129
1034836011350	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
1034836011351	Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair]; Region: UvrD; COG0210
1034836011352	Part of AAA domain; Region: AAA_19; pfam13245
1034836011353	AAA ATPase domain; Region: AAA_15; pfam13175
1034836011354	TOPRIM_OLD: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in bacterial and archaeal nucleases of the OLD (overcome lysogenization defect) family.  The bacteriophage P2 OLD protein, which has DNase as well as...; Region: TOPRIM_OLD; cd01026
1034836011355	putative active site [active]
1034836011356	putative metal-binding site [ion binding]; other site
1034836011357	rRNA large subunit methyltransferase; Provisional; Region: PRK00103
1034836011358	CxxH/CxxC protein, BA_5709 family; Region: CxxH_BA5709; TIGR04129
1034836011359	Uncharacterized distant relative of cell wall-associated hydrolases [Function unknown]; Region: COG3863
1034836011360	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1034836011361	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1034836011362	active site
1034836011363	catalytic tetrad [active]
1034836011364	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1034836011365	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1034836011366	Coenzyme A binding pocket [chemical binding]; other site
1034836011367	Tetratricopeptide repeat; Region: TPR_12; pfam13424
1034836011368	Tetratricopeptide repeat; Region: TPR_12; pfam13424
1034836011369	Arginase family; Region: Arginase; cd09989
1034836011370	agmatinase; Region: agmatinase; TIGR01230
1034836011371	active site
1034836011372	Mn binding site [ion binding]; other site
1034836011373	oligomer interface [polypeptide binding]; other site
1034836011374	S-methylmethionine transporter; Provisional; Region: PRK11387
1034836011375	ornithine--oxo-acid transaminase; Provisional; Region: rocD; PRK04073
1034836011376	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1034836011377	inhibitor-cofactor binding pocket; inhibition site
1034836011378	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1034836011379	catalytic residue [active]
1034836011380	Predicted integral membrane protein [Function unknown]; Region: COG5658
1034836011381	Protein of unknown function (DUF1648); Region: DUF1648; pfam07853
1034836011382	SdpI/YhfL protein family; Region: SdpI; pfam13630
1034836011383	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1034836011384	dimerization interface [polypeptide binding]; other site
1034836011385	putative DNA binding site [nucleotide binding]; other site
1034836011386	putative Zn2+ binding site [ion binding]; other site
1034836011387	PAS domain; Region: PAS_9; pfam13426
1034836011388	psp operon transcriptional activator PspF; Region: phageshock_pspF; TIGR02974
1034836011389	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1034836011390	Walker A motif; other site
1034836011391	ATP binding site [chemical binding]; other site
1034836011392	Walker B motif; other site
1034836011393	arginine finger; other site
1034836011394	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
1034836011395	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1034836011396	putative substrate translocation pore; other site
1034836011397	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1034836011398	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1034836011399	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1034836011400	dimerization interface [polypeptide binding]; other site
1034836011401	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1034836011402	dimer interface [polypeptide binding]; other site
1034836011403	phosphorylation site [posttranslational modification]
1034836011404	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1034836011405	ATP binding site [chemical binding]; other site
1034836011406	Mg2+ binding site [ion binding]; other site
1034836011407	G-X-G motif; other site
1034836011408	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1034836011409	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1034836011410	active site
1034836011411	phosphorylation site [posttranslational modification]
1034836011412	intermolecular recognition site; other site
1034836011413	dimerization interface [polypeptide binding]; other site
1034836011414	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1034836011415	DNA binding site [nucleotide binding]
1034836011416	Peptidase propeptide and YPEB domain; Region: PepSY; pfam03413
1034836011417	Peptidase propeptide and YPEB domain; Region: PepSY; pfam03413
1034836011418	Peptidase propeptide and YPEB domain; Region: PepSY; pfam03413
1034836011419	Predicted membrane protein [Function unknown]; Region: COG3212
1034836011420	Peptidase propeptide and YPEB domain; Region: PepSY; pfam03413
1034836011421	periplasmic serine pepetdase DegS; Region: protease_degS; TIGR02038
1034836011422	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
1034836011423	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1034836011424	protein binding site [polypeptide binding]; other site
1034836011425	Metal-dependent hydrolases of the beta-lactamase superfamily I [General function prediction only]; Region: PhnP; COG1235
1034836011426	YycH protein; Region: YycI; cl02015
1034836011427	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4863
1034836011428	YycH protein; Region: YycH; pfam07435
1034836011429	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: VicK; COG5002
1034836011430	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1034836011431	dimerization interface [polypeptide binding]; other site
1034836011432	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1034836011433	putative active site [active]
1034836011434	heme pocket [chemical binding]; other site
1034836011435	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1034836011436	dimer interface [polypeptide binding]; other site
1034836011437	phosphorylation site [posttranslational modification]
1034836011438	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1034836011439	ATP binding site [chemical binding]; other site
1034836011440	Mg2+ binding site [ion binding]; other site
1034836011441	G-X-G motif; other site
1034836011442	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1034836011443	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1034836011444	active site
1034836011445	phosphorylation site [posttranslational modification]
1034836011446	intermolecular recognition site; other site
1034836011447	dimerization interface [polypeptide binding]; other site
1034836011448	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1034836011449	DNA binding site [nucleotide binding]
1034836011450	Adenylosuccinate synthetase; Region: Adenylsucc_synt; smart00788
1034836011451	Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the...; Region: AdSS; cd03108
1034836011452	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1034836011453	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cd06587
1034836011454	active site
1034836011455	replicative DNA helicase; Provisional; Region: PRK05748
1034836011456	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
1034836011457	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
1034836011458	Walker A motif; other site
1034836011459	ATP binding site [chemical binding]; other site
1034836011460	Walker B motif; other site
1034836011461	DNA binding loops [nucleotide binding]
1034836011462	Uncharacterized protein conserved in bacteria (DUF2188); Region: DUF2188; pfam09954
1034836011463	YycC-like protein; Region: YycC; pfam14174
1034836011464	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1034836011465	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
1034836011466	Phosphotransferase enzyme family; Region: APH; pfam01636
1034836011467	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cl17270
1034836011468	Predicted ATP-grasp enzyme [General function prediction only]; Region: COG3919
1034836011469	ATP-grasp domain; Region: ATP-grasp_4; pfam13535
1034836011470	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1034836011471	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
1034836011472	Uncharacterized proteins, LmbE homologs [Function unknown]; Region: COG2120
1034836011473	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cd05120
1034836011474	active site
1034836011475	substrate binding site [chemical binding]; other site
1034836011476	ATP binding site [chemical binding]; other site
1034836011477	50S ribosomal protein L9; Reviewed; Region: rplI; PRK00137
1034836011478	Ribosomal protein L9, N-terminal domain; Region: Ribosomal_L9_N; pfam01281
1034836011479	Ribosomal protein L9, C-terminal domain; Region: Ribosomal_L9_C; pfam03948
1034836011480	Predicted signaling protein consisting of a modified GGDEF domain and a DHH domain [Signal transduction mechanisms]; Region: COG3887
1034836011481	diguanylate cyclase; Region: GGDEF; smart00267
1034836011482	DHH family; Region: DHH; pfam01368
1034836011483	Predicted membrane protein (DUF2232); Region: DUF2232; pfam09991
1034836011484	Spore coat protein [Cell envelope biogenesis, outer membrane]; Region: COG5577
1034836011485	Predicted transcriptional regulators [Transcription]; Region: COG1733
1034836011486	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
1034836011487	putative manganese-dependent inorganic pyrophosphatase; Provisional; Region: PRK05427
1034836011488	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cl15354
1034836011489	DHHA2 domain; Region: DHHA2; pfam02833
1034836011490	EamA-like transporter family; Region: EamA; pfam00892
1034836011491	EamA-like transporter family; Region: EamA; pfam00892
1034836011492	Glycosyl hydrolase family 68, includes levansucrase, beta-fructofuranosidase and inulosucrase; Region: GH68; cd08997
1034836011493	active site
1034836011494	Beta-fructosidases (levanase/invertase) [Carbohydrate transport and metabolism]; Region: SacC; COG1621
1034836011495	Glycosyl hydrolase family 32, beta-fructosidases; Region: GH32_B_Fructosidase; cd08996
1034836011496	substrate binding [chemical binding]; other site
1034836011497	active site
1034836011498	Glycosyl hydrolases family 32 C terminal; Region: Glyco_hydro_32C; pfam08244
1034836011499	phosphonate utilization associated transcriptional regulator; Region: phnR_burk; TIGR03338
1034836011500	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1034836011501	DNA-binding site [nucleotide binding]; DNA binding site
1034836011502	FCD domain; Region: FCD; pfam07729
1034836011503	Uncharacterized protein conserved in bacteria [Function unknown]; Region: DinB; COG2318
1034836011504	H+ Antiporter protein; Region: 2A0121; TIGR00900
1034836011505	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cl17904
1034836011506	putative substrate translocation pore; other site
1034836011507	Protein of unknown function (DUF1304); Region: DUF1304; pfam06993
1034836011508	Nitroreductase-like family 1. A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and...; Region: Nitroreductase_1; cd02137
1034836011509	dimer interface [polypeptide binding]; other site
1034836011510	FMN binding site [chemical binding]; other site
1034836011511	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1034836011512	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1034836011513	putative DNA binding site [nucleotide binding]; other site
1034836011514	putative Zn2+ binding site [ion binding]; other site
1034836011515	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
1034836011516	Uncharacterized conserved protein [Function unknown]; Region: COG1284
1034836011517	Uncharacterized protein conserved in bacteria (DUF2179); Region: DUF2179; pfam10035
1034836011518	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1034836011519	MarR family; Region: MarR; pfam01047
1034836011520	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
1034836011521	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1034836011522	Coenzyme A binding pocket [chemical binding]; other site
1034836011523	DinB superfamily; Region: DinB_2; pfam12867
1034836011524	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
1034836011525	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1034836011526	DNA-binding site [nucleotide binding]; DNA binding site
1034836011527	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1034836011528	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1034836011529	homodimer interface [polypeptide binding]; other site
1034836011530	catalytic residue [active]
1034836011531	EamA-like transporter family; Region: EamA; pfam00892
1034836011532	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
1034836011533	EamA-like transporter family; Region: EamA; pfam00892
1034836011534	Reverse transcriptase (RNA-dependent DNA polymerase); Region: RVT_1; pfam00078
1034836011535	RT_Bac_retron_II: Reverse transcriptases (RTs) in bacterial retrotransposons or retrons. The polymerase reaction of this enzyme leads to the production of a unique RNA-DNA complex called msDNA (multicopy single-stranded (ss)DNA) in which a small ssDNA...; Region: RT_Bac_retron_II; cd03487
1034836011536	putative active site [active]
1034836011537	putative NTP binding site [chemical binding]; other site
1034836011538	putative nucleic acid binding site [nucleotide binding]; other site
1034836011539	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
1034836011540	Highly conserved protein containing a thioredoxin domain [Posttranslational modification, protein turnover, chaperones]; Region: COG1331
1034836011541	TRX domain, SSP411 protein family; members of this family are highly conserved proteins present in eukaryotes, bacteria and archaea, about 600-800 amino acids in length, which contain a TRX domain with a redox active CXXC motif. The human/rat protein; Region: SSP411; cd02955
1034836011542	catalytic residues [active]
1034836011543	CAAX protease self-immunity; Region: Abi; pfam02517
1034836011544	benzoate transport; Region: 2A0115; TIGR00895
1034836011545	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1034836011546	putative substrate translocation pore; other site
1034836011547	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1034836011548	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_3; cd07241
1034836011549	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1034836011550	putative metal binding site [ion binding]; other site
1034836011551	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1034836011552	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1034836011553	DNA binding site [nucleotide binding]
1034836011554	domain linker motif; other site
1034836011555	Ligand-binding domain of a novel transcription factor implicated in catabolite repression in Bacillus and Clostridium species; Region: PBP1_CcpB_like; cd06286
1034836011556	putative dimerization interface [polypeptide binding]; other site
1034836011557	putative ligand binding site [chemical binding]; other site
1034836011558	Human Ape1-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases; Region: Ape1-like_AP-endo; cd09087
1034836011559	active site
1034836011560	putative catalytic site [active]
1034836011561	DNA binding site [nucleotide binding]
1034836011562	putative phosphate binding site [ion binding]; other site
1034836011563	metal binding site A [ion binding]; metal-binding site
1034836011564	AP binding site [nucleotide binding]; other site
1034836011565	metal binding site B [ion binding]; metal-binding site
1034836011566	Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]; Region: Ada; COG0350
1034836011567	6-O-methylguanine DNA methyltransferase, ribonuclease-like domain; Region: Methyltransf_1N; pfam02870
1034836011568	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
1034836011569	DNA binding site [nucleotide binding]
1034836011570	active site
1034836011571	Adenosine deaminase [Nucleotide transport and metabolism]; Region: Ada; COG2169
1034836011572	Metal binding domain of Ada; Region: Ada_Zn_binding; pfam02805
1034836011573	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1034836011574	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1034836011575	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
1034836011576	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
1034836011577	dimer interface [polypeptide binding]; other site
1034836011578	ssDNA binding site [nucleotide binding]; other site
1034836011579	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1034836011580	30S ribosomal protein S6; Reviewed; Region: rpsF; PRK00453
1034836011581	GTP-binding protein YchF; Reviewed; Region: PRK09601
1034836011582	YchF GTPase; Region: YchF; cd01900
1034836011583	G1 box; other site
1034836011584	GTP/Mg2+ binding site [chemical binding]; other site
1034836011585	Switch I region; other site
1034836011586	G2 box; other site
1034836011587	Switch II region; other site
1034836011588	G3 box; other site
1034836011589	G4 box; other site
1034836011590	G5 box; other site
1034836011591	TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867
1034836011592	Anaerobic dehydrogenases, typically selenocysteine-containing [Energy production and conversion]; Region: BisC; COG0243
1034836011593	The MopB_3 CD includes a group of related uncharacterized bacterial and archaeal molybdopterin-binding oxidoreductase-like domains with a putative N-terminal iron-sulfur [4Fe-4S] cluster binding site and molybdopterin cofactor binding site. These members...; Region: MopB_3; cd02766
1034836011594	putative [4Fe-4S] binding site [ion binding]; other site
1034836011595	putative molybdopterin cofactor binding site [chemical binding]; other site
1034836011596	Molybdopterin-Binding, C-terminal (MopB_CT) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum-...; Region: MopB_CT; cl09929
1034836011597	molybdopterin cofactor binding site; other site
1034836011598	Bacterial protein of unknown function (DUF951); Region: DUF951; pfam06107
1034836011599	Uncharacterized membrane protein [Function unknown]; Region: COG3949
1034836011600	Spore germination protein; Region: Spore_permease; cl17796
1034836011601	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
1034836011602	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1034836011603	Coenzyme A binding pocket [chemical binding]; other site
1034836011604	putative sporulation protein YyaC; Region: spore_YyaC; TIGR02841
1034836011605	ParB/RepB/Spo0J family partition protein; Region: parB_part; TIGR00180
1034836011606	ParB-like nuclease domain; Region: ParB; smart00470
1034836011607	KorB domain; Region: KorB; pfam08535
1034836011608	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
1034836011609	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
1034836011610	P-loop; other site
1034836011611	Magnesium ion binding site [ion binding]; other site
1034836011612	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
1034836011613	Magnesium ion binding site [ion binding]; other site
1034836011614	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
1034836011615	nucleoid occlusion protein; Region: nucleoid_noc; TIGR04285
1034836011616	ParB-like nuclease domain; Region: ParB; smart00470
1034836011617	Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division [Cell envelope biogenesis, outer membrane]; Region: GidB; COG0357
1034836011618	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1034836011619	S-adenosylmethionine binding site [chemical binding]; other site
1034836011620	tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; Validated; Region: PRK05192
1034836011621	NAD(FAD)-utilizing enzyme possibly involved in translation [Translation, ribosomal structure and biogenesis]; Region: Gid; COG1206
1034836011622	GidA associated domain 3; Region: GIDA_assoc_3; pfam13932
1034836011623	tRNA modification GTPase TrmE; Reviewed; Region: trmE; PRK05291
1034836011624	GTP-binding protein TrmE N-terminus; Region: TrmE_N; pfam10396
1034836011625	trmE is a tRNA modification GTPase; Region: trmE; cd04164
1034836011626	G1 box; other site
1034836011627	GTP/Mg2+ binding site [chemical binding]; other site
1034836011628	Switch I region; other site
1034836011629	G2 box; other site
1034836011630	Switch II region; other site
1034836011631	G3 box; other site
1034836011632	G4 box; other site
1034836011633	G5 box; other site
1034836011634	Catalytic cysteine-containing C-terminus of GTPase, MnmE; Region: GTPase_Cys_C; pfam12631
1034836011635	Predicted RNA-binding protein [General function prediction only]; Region: Jag; COG1847
1034836011636	jag_K homology RNA-binding domain. The KH domain is found in proteins homologous to the Bacillus subtilis protein Jag, which is associated with SpoIIIJ and is necessary for the third stage of sporulation.  The KH motif is a beta-alpha-alpha-beta-beta...; Region: jag_KH; cd02414
1034836011637	G-X-X-G motif; other site
1034836011638	R3H domain found in proteins homologous to Bacillus subtilus Jag, which is associated with SpoIIIJ. SpoIIIJ is necessary for the third stage of sporulation. The name of the R3H domain comes from the characteristic spacing of the most conserved arginine...; Region: R3H_jag; cd02644
1034836011639	RxxxH motif; other site
1034836011640	OxaA-like protein precursor; Validated; Region: PRK02944
1034836011641	Preprotein translocase subunit YidC [Intracellular trafficking and secretion]; Region: YidC; COG0706
1034836011642	ribonuclease P; Reviewed; Region: rnpA; PRK00499