-- dump date 20240507_081832 -- class Genbank::CDS -- table cds_note -- id note AKAW2_10001S InterPro:IPR011329,IPR029167; PFAM:PF15474; SECRETED:SignalP(1-17); go_component: GO:0005576 - extracellular region [Evidence IEA]; go_process: GO:0009405 - pathogenesis [Evidence IEA] AKAW2_10002A COG:S; EggNog:ENOG410PTCG; SECRETED:SignalP(1-19); TransMembrane:1 (n2-12c17/18o172-196i) AKAW2_10003A COG:C; EggNog:ENOG410PMUN; InterPro:IPR011032,IPR020843,IPR036291; PFAM:PF13602,PF00107; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA] AKAW2_10004A COG:S; EggNog:ENOG410Q2P1 AKAW2_10005A COG:P; EggNog:ENOG410PMUG; InterPro:IPR004481,IPR004837; PFAM:PF01699; TransMembrane:10 (o6-24i44-65o71-95i107-125o131-152i212-232o244-265i277- 304o310-331i338-356o); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_10006A COG:S; EggNog:ENOG410Q2CG AKAW2_10007S SECRETED:SignalP(1-20) AKAW2_10008A COG:S; EggNog:ENOG410PNMF; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF04082; TransMembrane:3 (o366-384i543-560o643-664i); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_10009A COG:G; EggNog:ENOG410QDAM; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i30-58o70-87i99-119o125-145i157-183o189-209i233-254o266- 284i296-316o322-350i362-382o388-413i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_10010A CAZy:PL1; COG:G; EggNog:ENOG410PIPP; InterPro:IPR012334,IPR002022,IPR011050; PFAM:PF00544; SECRETED:SignalP(1-20) AKAW2_10012S COG:S; EggNog:ENOG410PSER; InterPro:IPR000182,IPR016181; PFAM:PF13508; go_function: GO:0008080 - N-acetyltransferase activity [Evidence IEA] AKAW2_10011A COG:S; EggNog:ENOG410PY1F; TransMembrane:6 (o15-37i49-70o90-111i123-144o164-185i197-215o) AKAW2_10013S COG:E; EggNog:ENOG410PIEB; InterPro:IPR002293; PFAM:PF00324,PF13520; TransMembrane:12 (i50-72o84-108i129-154o174-193i200-222o242-261i282- 304o334-356i383-403o409-433i453-473o485-505i); go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_10014A COG:S; EggNog:ENOG410PGN5; InterPro:IPR025340; PFAM:PF14033 AKAW2_10015A COG:S; EggNog:ENOG410PZYI; InterPro:IPR002889; PFAM:PF01822; TransMembrane:2 (o35-54i66-85o) AKAW2_10017S COG:S; EggNog:ENOG410PY41; SECRETED:SignalP(1-22) AKAW2_10018A COG:G; EggNog:ENOG410PMG2; InterPro:IPR008922,IPR002227; PFAM:PF00264; SECRETED:SignalP(1-20); go_function: GO:0016491 - oxidoreductase activity [Evidence IEA] AKAW2_10019S COG:S; EggNog:ENOG410PWYB; TransMembrane:7 (o29-50i62-85o105-128i140-169o189-210i222-240o260-280i) AKAW2_10020S CAZy:CBM24; COG:G; EggNog:ENOG410PJGT; InterPro:IPR005197; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_10022S COG:S; EggNog:ENOG410PY1P; SECRETED:SignalP(1-16) AKAW2_10023S COG:G; EggNog:ENOG410QDWX; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690,PF00083; TransMembrane:12 (i62-80o100-118i130-148o160-182i189-212o218-238i303- 328o340-367i388-409o415-439i451-469o481-503i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_10024A COG:S; EggNog:ENOG410PYG3; InterPro:IPR025363; PFAM:PF14087; SECRETED:SignalP(1-23); TransMembrane:2 (n9-20c25/26o87-108i120-137o) AKAW2_10025A COG:O; EggNog:ENOG410PR7B; InterPro:IPR008978,IPR031107,IPR002068; PFAM:PF00011 AKAW2_10027S COG:J; EggNog:ENOG410PKI1; InterPro:IPR023631,IPR036928; PFAM:PF01425 AKAW2_10028A COG:S; EggNog:ENOG410Q1TK; TransMembrane:6 (o20-44i56-74o96-120i132-153o173-195i207-229o) AKAW2_10029S COG:E; EggNog:ENOG410PMJG; InterPro:IPR002293,IPR004840; PFAM:PF13520,PF00324; TransMembrane:12 (i42-59o79-102i123-147o167-187i199-220o240-257i278- 298o340-359i379-399o405-429i450-470o482-500i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0006865 - amino acid transport [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_10030S COG:S; EggNog:ENOG410PRIM; InterPro:IPR010451,IPR023375; PFAM:PF06314; go_function: GO:0016829 - lyase activity [Evidence IEA] AKAW2_10031A CAZy:AA7; COG:C; EggNog:ENOG410PKSP; InterPro:IPR006094,IPR036318,IPR016166,IPR012951; PFAM:PF08031,PF01565; SECRETED:SignalP(1-21); go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_function: GO:0071949 - FAD binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_10032S COG:S; EggNog:ENOG410QDES; TransMembrane:7 (o20-38i54-74o111-133i145-168o213-235i247-269o289-309i) AKAW2_10033A COG:E; EggNog:ENOG410Q1CB; InterPro:IPR012001,IPR012000,IPR011766,IPR029061, IPR039368,IPR029035,IPR000399; PFAM:PF02775,PF02776,PF00205; go_function: GO:0000287 - magnesium ion binding [Evidence IEA]; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0030976 - thiamine pyrophosphate binding [Evidence IEA] AKAW2_10035S COG:Q; EggNog:ENOG410PQ3K; InterPro:IPR005128; PFAM:PF03306; go_function: GO:0047605 - acetolactate decarboxylase activity [Evidence IEA]; go_process: GO:0045151 - acetoin biosynthetic process [Evidence IEA] AKAW2_10034A CAZy:GH30; COG:G; EggNog:ENOG410PPTR; InterPro:IPR017853,IPR033453,IPR033452,IPR001139; PFAM:PF17189,PF02055; SECRETED:SignalP(1-26); go_function: GO:0004348 - glucosylceramidase activity [Evidence IEA]; go_process: GO:0006665 - sphingolipid metabolic process [Evidence IEA] AKAW2_10036S COG:S; EggNog:ENOG410PW14; TransMembrane:1 (o584-610i); antiSMASH:Cluster_1.1 AKAW2_10037S COG:S; EggNog:ENOG410PQY4; antiSMASH:Cluster_1.1 AKAW2_10038S COG:S; EggNog:ENOG410PQY4; antiSMASH:Cluster_1.1 AKAW2_10039A COG:S; EggNog:ENOG410PU0M; InterPro:IPR011009; antiSMASH:Cluster_1.1 AKAW2_10040A COG:K; EggNog:ENOG410Q2P5; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172; antiSMASH:Cluster_1.1; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_10041A COG:G; EggNog:ENOG410PMPY; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; SMCOG1005:Drug resistance transporter, EmrB/QacA; TransMembrane:13 (o44-70i82-100o112-129i169-187o199-221i233-256o268- 286i298-317o337-358i370-389o401-420i432-456o515-534i); antiSMASH:Cluster_1.1; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_10042A COG:E; EggNog:ENOG410PFSG; InterPro:IPR004839,IPR015424,IPR015421,IPR015422; PFAM:PF00155; SMCOG1109:8-amino-7-oxononanoate synthase; antiSMASH:Cluster_1.1; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0030170 - pyridoxal phosphate binding [Evidence IEA]; go_process: GO:0009058 - biosynthetic process [Evidence IEA] AKAW2_10043S COG:Q; EggNog:ENOG410QD82; InterPro:IPR016036,IPR016035,IPR029063,IPR016039, IPR042104,IPR014030,IPR014031,IPR001227,IPR032821, IPR014043,IPR020807,IPR020841,IPR013217; PFAM:PF16197,PF13489,PF02801,PF00698,PF13847, PF13649,PF14765,PF00109,PF08242,PF08241; SMCOG1022:Beta-ketoacyl synthase; antiSMASH:Cluster_1.1; go_function: GO:0016740 - transferase activity [Evidence IEA]; go_function: GO:0016746 - transferase activity, transferring acyl groups [Evidence IEA] AKAW2_10044S COG:Q; EggNog:ENOG410QD82; InterPro:IPR009081,IPR013149,IPR036736,IPR036291, IPR020806,IPR011032,IPR013968,IPR020843; PFAM:PF00107,PF00106,PF08659,PF00550,PF13602; SMCOG1028:crotonyl-CoA reductase / alcohol dehydrogenase; antiSMASH:Cluster_1.1; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0031177 - phosphopantetheine binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_10045S COG:S; EggNog:ENOG410PY4T; InterPro:IPR011009; antiSMASH:Cluster_1.1 AKAW2_10046S COG:E; EggNog:ENOG410PGUG; InterPro:IPR013057; PFAM:PF01490; TransMembrane:11 (i137-156o168-187i225-243o249-269i281-303o347-363i375- 397o417-438i480-500o506-530i568-593o) AKAW2_10047S CAZy:GH76; COG:G; EggNog:ENOG410PFRH; InterPro:IPR014480,IPR008928,IPR005198; PFAM:PF03663; SECRETED:SignalP(1-28); TransMembrane:1 (n13-24c28/29o441-462i); go_function: GO:0008496 - mannan endo-1,6-alpha-mannosidase activity [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA]; go_process: GO:0016052 - carbohydrate catabolic process [Evidence IEA] AKAW2_10048S COG:Q; EggNog:ENOG410PF88; InterPro:IPR000269,IPR015798,IPR016182,IPR036460; PFAM:PF01179; go_function: GO:0005507 - copper ion binding [Evidence IEA]; go_function: GO:0008131 - primary amine oxidase activity [Evidence IEA]; go_function: GO:0048038 - quinone binding [Evidence IEA]; go_process: GO:0009308 - amine metabolic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_10049S COG:S; EggNog:ENOG410PTBF AKAW2_10050A COG:D,P; EggNog:ENOG410PGV0; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:11 (i48-68o74-94i106-125o137-159i171-190o196-221i241-260o280- 298i305-329o335-355i442-460o); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_10051S COG:K; EggNog:ENOG410PMRV; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_10052S COG:S; EggNog:ENOG410PRRT; InterPro:IPR038903; SECRETED:SignalP(1-18); go_component: GO:0005576 - extracellular region [Evidence IEA]; go_function: GO:0019863 - IgE binding [Evidence IEA] AKAW2_10053A COG:A; EggNog:ENOG410PSFX; InterPro:IPR000999,IPR036389; PFAM:PF00636,PF14622; antiSMASH:Cluster_1.2; go_function: GO:0004525 - ribonuclease III activity [Evidence IEA]; go_process: GO:0006396 - RNA processing [Evidence IEA] AKAW2_10054A antiSMASH:Cluster_1.2 AKAW2_10055A COG:S; EggNog:ENOG410PZBI; SECRETED:SignalP(1-19); antiSMASH:Cluster_1.2 AKAW2_10056S SECRETED:SignalP(1-22); antiSMASH:Cluster_1.2 AKAW2_10057S COG:S; EggNog:ENOG410Q013; TransMembrane:1 (o330-350i); antiSMASH:Cluster_1.2 AKAW2_10058S COG:H; EggNog:ENOG410PXDT; InterPro:IPR008949,IPR000092; PFAM:PF00348; SMCOG1182:Polyprenyl synthetase; TransMembrane:1 (i12-32o); antiSMASH:Cluster_1.2; go_process: GO:0008299 - isoprenoid biosynthetic process [Evidence IEA] AKAW2_10059S COG:H; EggNog:ENOG410Q248; InterPro:IPR033749,IPR008949,IPR000092; PFAM:PF00348; SMCOG1182:Polyprenyl synthetase; antiSMASH:Cluster_1.2; go_process: GO:0008299 - isoprenoid biosynthetic process [Evidence IEA] AKAW2_10060A COG:S; EggNog:ENOG410PRQY; InterPro:IPR011009,IPR002575; antiSMASH:Cluster_1.2 AKAW2_10061A COG:V; EggNog:ENOG410PJT2; InterPro:IPR036291,IPR001509; PFAM:PF07993,PF01370; SMCOG1010:NAD-dependent epimerase/dehydratase; antiSMASH:Cluster_1.2; go_function: GO:0003824 - catalytic activity [Evidence IEA] AKAW2_10062A CAZy:GH10; COG:G; EggNog:ENOG410PHN8; InterPro:IPR017853,IPR031158,IPR001000; PFAM:PF00331; SECRETED:SignalP(1-19); antiSMASH:Cluster_1.2; go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_10063S CAZy:GH62; COG:G; EggNog:ENOG410PJ53; InterPro:IPR005193,IPR023296; PFAM:PF03664; antiSMASH:Cluster_1.2; go_function: GO:0046556 - alpha-L-arabinofuranosidase activity [Evidence IEA]; go_process: GO:0046373 - L-arabinose metabolic process [Evidence IEA] AKAW2_10064S COG:S; EggNog:ENOG410PKSA; InterPro:IPR011009 AKAW2_10065A COG:S; EggNog:ENOG410PXBC AKAW2_10067S COG:S; EggNog:ENOG410PVD5; InterPro:IPR008427; PFAM:PF05730; SECRETED:SignalP(1-20); TransMembrane:6 (n6-17c25/26o101-119i131-151o180-201i208-227o255-280i292- 316o) AKAW2_10068A COG:O; EggNog:ENOG410PHFF; InterPro:IPR036852,IPR015366,IPR030400; MEROPS:MER0005329; PFAM:PF09286; SECRETED:SignalP(1-18); go_function: GO:0004252 - serine-type endopeptidase activity [Evidence IEA]; go_function: GO:0008236 - serine-type peptidase activity [Evidence IEA]; go_process: GO:0006508 - proteolysis [Evidence IEA] AKAW2_10069A COG:C; EggNog:ENOG410PGDD; InterPro:IPR016166,IPR016167,IPR006094,IPR036318, IPR016169; SECRETED:SignalP(1-25); go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_function: GO:0071949 - FAD binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_10070S CAZy:GH5; COG:G; EggNog:ENOG410PKCC; InterPro:IPR017853,IPR001547; PFAM:PF00150; SECRETED:SignalP(1-23); go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_process: GO:0071704 - organic substance metabolic process [Evidence IEA] AKAW2_10071S COG:S; EggNog:ENOG410PWCM; InterPro:IPR042183,IPR036148,IPR005656; PFAM:PF03972; go_function: GO:0016829 - lyase activity [Evidence IEA] AKAW2_10072A SECRETED:SignalP(1-19) AKAW2_10073A COG:M; EggNog:ENOG410PUFY; InterPro:IPR029044,IPR007577,IPR039367; PFAM:PF04488; go_function: GO:0000009 - alpha-1,6-mannosyltransferase activity [Evidence IEA] AKAW2_10074S COG:C; EggNog:ENOG410PG0F; InterPro:IPR018108,IPR023395; PFAM:PF00153 AKAW2_10075A COG:E; EggNog:ENOG410PMF9; InterPro:IPR004839,IPR000796,IPR015424,IPR015421, IPR015422; PFAM:PF00155; SECRETED:SignalP(1-31); go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0008483 - transaminase activity [Evidence IEA]; go_function: GO:0030170 - pyridoxal phosphate binding [Evidence IEA]; go_process: GO:0006520 - cellular amino acid metabolic process [Evidence IEA]; go_process: GO:0009058 - biosynthetic process [Evidence IEA] AKAW2_10077A COG:S; EggNog:ENOG410PKT1; InterPro:IPR010699; PFAM:PF06912; TransMembrane:6 (i50-73o97-117i129-150o189-210i222-241o247-266i) AKAW2_10076S COG:G; EggNog:ENOG410PHMM; InterPro:IPR006045,IPR014710,IPR011051,IPR017774; PFAM:PF07883,PF00190; SECRETED:SignalP(1-26); go_process: GO:0033609 - oxalate metabolic process [Evidence IEA] AKAW2_10078A COG:S; EggNog:ENOG410PY5J AKAW2_10079A COG:S; EggNog:ENOG410PSW1; TransMembrane:4 (i66-87o107-126i157-180o569-590i) AKAW2_10080S COG:S; EggNog:ENOG410PHQA; InterPro:IPR007461; PFAM:PF04366 AKAW2_10081S COG:S; EggNog:ENOG410PNJZ; InterPro:IPR036291,IPR016040; PFAM:PF13460 AKAW2_10082A COG:S; EggNog:ENOG410PWTR; InterPro:IPR005645,IPR029058; PFAM:PF03959 AKAW2_10083S COG:M; EggNog:ENOG410PMQ8; InterPro:IPR001509,IPR036291; PFAM:PF04321,PF01073,PF16363,PF07993,PF01370; go_function: GO:0003824 - catalytic activity [Evidence IEA] AKAW2_10084S COG:S; EggNog:ENOG410PI62; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; TransMembrane:1 (o580-601i); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_10086A COG:T; EggNog:ENOG410PGVB; InterPro:IPR000651,IPR036964,IPR019804,IPR023578, IPR008937,IPR001895; PFAM:PF00617,PF00618; TransMembrane:1 (i42-61o); go_function: GO:0005085 - guanyl-nucleotide exchange factor activity [Evidence IEA]; go_process: GO:0007264 - small GTPase mediated signal transduction [Evidence IEA] AKAW2_10087A COG:G; EggNog:ENOG410QE3G; InterPro:IPR011701,IPR036259; PFAM:PF07690; TransMembrane:14 (i87-104o124-142i154-171o177-199i211-230o242-265i297- 320o326-346i366-388o408-427i434-452o458-478i499-519o570- 592i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_10088S COG:S; EggNog:ENOG410PP6I; InterPro:IPR012312; PFAM:PF01814 AKAW2_10089S BUSCO:EOG09260WYQ; COG:J; EggNog:ENOG410PG6P; InterPro:IPR020056,IPR000924,IPR020059,IPR020058, IPR001412,IPR014729,IPR004514,IPR011035; PFAM:PF00749,PF03950; go_component: GO:0005737 - cytoplasm [Evidence IEA]; go_function: GO:0000166 - nucleotide binding [Evidence IEA]; go_function: GO:0004812 - aminoacyl-tRNA ligase activity [Evidence IEA]; go_function: GO:0004819 - glutamine-tRNA ligase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006412 - translation [Evidence IEA]; go_process: GO:0006418 - tRNA aminoacylation for protein translation [Evidence IEA]; go_process: GO:0006425 - glutaminyl-tRNA aminoacylation [Evidence IEA]; go_process: GO:0043039 - tRNA aminoacylation [Evidence IEA] AKAW2_10090S COG:S; EggNog:ENOG410PHNS; InterPro:IPR036691; SECRETED:SignalP(1-19) AKAW2_10091S COG:S; EggNog:ENOG410PNYD; TransMembrane:7 (o12-32i44-65o85-109i121-141o168-194i206-224o244-264i) AKAW2_10092A BUSCO:EOG092620EL; COG:F; EggNog:ENOG410Q2V5; InterPro:IPR017456,IPR027417,IPR029062,IPR017926, IPR004468,IPR033828; MEROPS:MER0437468; PFAM:PF07722,PF00117,PF06418; go_function: GO:0003883 - CTP synthase activity [Evidence IEA]; go_process: GO:0006221 - pyrimidine nucleotide biosynthetic process [Evidence IEA]; go_process: GO:0006241 - CTP biosynthetic process [Evidence IEA] AKAW2_10093S COG:S; EggNog:ENOG410PW90; InterPro:IPR040632,IPR027417; PFAM:PF17784; TransMembrane:1 (i236-254o) AKAW2_10094S COG:E; EggNog:ENOG410PJ3P; InterPro:IPR013154,IPR013149,IPR015421,IPR036291, IPR001597,IPR015424,IPR011032,IPR002328,IPR020843, IPR015422; PFAM:PF00107,PF01212,PF08240; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0016829 - lyase activity [Evidence IEA]; go_process: GO:0006520 - cellular amino acid metabolic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_10095A COG:Q; EggNog:ENOG410PN00; InterPro:IPR036291,IPR002347,IPR020904; PFAM:PF00106,PF13561; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_10096S COG:C,H; EggNog:ENOG410PJVZ; InterPro:IPR036188,IPR002938; PFAM:PF01494; TransMembrane:1 (n3-11c16/17o361-379i); go_function: GO:0071949 - FAD binding [Evidence IEA] AKAW2_10097A COG:S; EggNog:ENOG410PNJ8; TransMembrane:7 (o6-25i41-60o98-119i135-159o179-204i216-236o256-272i) AKAW2_10098A COG:G; EggNog:ENOG410PJWU; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i65-84o104-122i134-156o162-184i191-215o235-257i347- 369o389-412i419-438o444-465i485-502o508-526i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_10099A COG:Q; EggNog:ENOG410PIRX; InterPro:IPR026992,IPR027443,IPR005123; PFAM:PF03171,PF14226; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_10100S COG:G; EggNog:ENOG410PJJE; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i35-53o80-102i109-128o134-158i170-191o203-223i273- 296o308-325i337-358o364-385i397-418o430-451i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_10101S COG:K; EggNog:ENOG410PJ1I; InterPro:IPR036236,IPR013087,IPR007219; PFAM:PF04082; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA] AKAW2_10102A InterPro:IPR016446,IPR029479,IPR000415; PFAM:PF00881; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_10103A COG:S; EggNog:ENOG410PTWX; InterPro:IPR036864,IPR021858,IPR001138; PFAM:PF00172,PF11951; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_10104S TransMembrane:1 (i21-38o) AKAW2_10105A COG:C; EggNog:ENOG410PGTG; InterPro:IPR001155,IPR001711,IPR013785; PFAM:PF00724; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0004435 - phosphatidylinositol phospholipase C activity [Evidence IEA]; go_function: GO:0010181 - FMN binding [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0006629 - lipid metabolic process [Evidence IEA]; go_process: GO:0007165 - signal transduction [Evidence IEA]; go_process: GO:0035556 - intracellular signal transduction [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_10106S COG:F; EggNog:ENOG410PMHW; InterPro:IPR036683,IPR012675,IPR006058,IPR016208, IPR036884,IPR001041,IPR036010,IPR036318,IPR000674, IPR036856,IPR008274,IPR005107,IPR002888,IPR016169, IPR002346,IPR016166,IPR037165; PFAM:PF02738,PF00111,PF03450,PF01315,PF00941, PF01799; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0009055 - electron transfer activity [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0046872 - metal ion binding [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_function: GO:0051536 - iron-sulfur cluster binding [Evidence IEA]; go_function: GO:0051537 - 2 iron, 2 sulfur cluster binding [Evidence IEA]; go_function: GO:0071949 - FAD binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_10107A COG:C,H; EggNog:ENOG410PIAV; InterPro:IPR036188,IPR002938; TransMembrane:1 (i21-41o); go_function: GO:0071949 - FAD binding [Evidence IEA] AKAW2_10108S COG:Q; EggNog:ENOG410PMDD; InterPro:IPR002347,IPR036291,IPR020904; PFAM:PF00106,PF13561,PF08659; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_10109S COG:C,H; EggNog:ENOG410PJC1; InterPro:IPR036188,IPR002938,IPR036249,IPR038220, IPR012941; PFAM:PF07976,PF01494; go_function: GO:0071949 - FAD binding [Evidence IEA] AKAW2_10110A COG:O; EggNog:ENOG410PGZ9; InterPro:IPR027417,IPR000641,IPR003593,IPR003959; PFAM:PF00004; SECRETED:SignalP(1-20); go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA] AKAW2_10111A COG:E; EggNog:ENOG410Q2XF; InterPro:IPR004840,IPR004841; PFAM:PF13520,PF00324; TransMembrane:12 (i52-68o80-100i120-141o161-183i195-213o233-254i274- 293o326-347i368-389o401-422i443-468o480-501i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_process: GO:0006865 - amino acid transport [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_10112S COG:G; EggNog:ENOG410PJ41; InterPro:IPR005829,IPR005828,IPR003663,IPR036259, IPR020846; PFAM:PF00083,PF07690; TransMembrane:12 (i7-32o52-71i78-101o107-126i147-167o173-190i266-287o299- 316i323-344o370-394i406-425o437-455i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_10113S COG:S; EggNog:ENOG410PQJH AKAW2_10114S COG:S; EggNog:ENOG410Q2B7 AKAW2_10115A COG:U; EggNog:ENOG410PU1A; InterPro:IPR004695,IPR038665; PFAM:PF03595; TransMembrane:9 (o53-74i95-117o129-151i158-178o198-219i239-257o288- 309i321-341o353-372i); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_10116S COG:O,P; EggNog:ENOG410PFQK; InterPro:IPR041756,IPR003137,IPR007484,IPR029514; MEROPS:MER0001288; PFAM:PF02225,PF04389; SECRETED:SignalP(1-20); go_function: GO:0004177 - aminopeptidase activity [Evidence IEA]; go_process: GO:0006508 - proteolysis [Evidence IEA] AKAW2_10117S COG:E; EggNog:ENOG410PUH4; SECRETED:SignalP(1-18) AKAW2_10119A COG:E; EggNog:ENOG410PVQQ; InterPro:IPR002129,IPR015421,IPR015424,IPR021115, IPR010977; PFAM:PF00282,PF01212,PF00266; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0016831 - carboxy-lyase activity [Evidence IEA]; go_function: GO:0030170 - pyridoxal phosphate binding [Evidence IEA]; go_process: GO:0006520 - cellular amino acid metabolic process [Evidence IEA]; go_process: GO:0019752 - carboxylic acid metabolic process [Evidence IEA] AKAW2_10120A COG:Q; EggNog:ENOG410PNKN; InterPro:IPR008854,IPR029063; PFAM:PF05724,PF13649,PF13489,PF08241,PF13847; go_function: GO:0008757 - S-adenosylmethionine-dependent methyltransferase activity [Evidence IEA] AKAW2_10121S COG:S; EggNog:ENOG410PIJH; TransMembrane:7 (o20-40i61-80o155-173i185-203o286-304i316-335o372-394i); antiSMASH:Cluster_1.3 AKAW2_10122S COG:G; EggNog:ENOG410PU9A; InterPro:IPR005829,IPR005828,IPR003663,IPR036259, IPR020846; PFAM:PF00083,PF07690; SMCOG1169:sugar transport protein; TransMembrane:12 (i12-30o58-82i94-111o117-141i153-172o192-214i273-295o307- 326i338-355o367-392i404-428o434-455i); antiSMASH:Cluster_1.3; go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_10123A COG:S; EggNog:ENOG410PXPC; SECRETED:SignalP(1-19); antiSMASH:Cluster_1.3 AKAW2_10124A COG:O; EggNog:ENOG410PNF8; InterPro:IPR036249,IPR040079,IPR036282,IPR010987, IPR004045,IPR004046; PFAM:PF13409,PF00043,PF14497,PF13417,PF02798; SMCOG1193:glutathione S-transferase; antiSMASH:Cluster_1.3; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0006749 - glutathione metabolic process [Evidence IEA] AKAW2_10125A COG:P; EggNog:ENOG410PNY1; InterPro:IPR041891,IPR001148,IPR018338,IPR023561, IPR036398; PFAM:PF00194; antiSMASH:Cluster_1.3; go_function: GO:0004089 - carbonate dehydratase activity [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA] AKAW2_10126A CAZy:GH16; COG:G; EggNog:ENOG410PJB2; InterPro:IPR000757,IPR013320,IPR017168; PFAM:PF00722; SECRETED:SignalP(1-21); TransMembrane:1 (n6-16c21/22o310-330i); antiSMASH:Cluster_1.3; go_component: GO:0005618 - cell wall [Evidence IEA]; go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_function: GO:0016798 - hydrolase activity, acting on glycosyl bonds [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA]; go_process: GO:0071555 - cell wall organization [Evidence IEA] AKAW2_10127S COG:Q; EggNog:ENOG410QEEM; InterPro:IPR001613,IPR036188,IPR002937; PFAM:PF13450,PF01593; SECRETED:SignalP(1-18); antiSMASH:Cluster_1.3; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_10128A SECRETED:SignalP(1-17); antiSMASH:Cluster_1.3 AKAW2_10129A COG:I; EggNog:ENOG410PJU0; InterPro:IPR000873,IPR009081,IPR006162,IPR036736, IPR036291,IPR020806,IPR013120,IPR042099,IPR020845; PFAM:PF00501,PF00550,PF01370,PF07993; SMCOG1002:AMP-dependent synthetase and ligase; antiSMASH:Cluster_1.3; go_function: GO:0031177 - phosphopantetheine binding [Evidence IEA] AKAW2_10130A CAZy:GH142; COG:S; EggNog:ENOG410PKZ9; InterPro:IPR008979,IPR008928,IPR012341; SECRETED:SignalP(1-20); antiSMASH:Cluster_1.3; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_10131A COG:Q; EggNog:ENOG410PM9I; InterPro:IPR016036,IPR016035,IPR016039,IPR018201, IPR042104,IPR014030,IPR011032,IPR013968,IPR013154, IPR001227,IPR032821,IPR014031,IPR006162,IPR014043, IPR020806,IPR020807,IPR020843,IPR020841,IPR009081, IPR036736,IPR036291; PFAM:PF16197,PF00550,PF08659,PF13561,PF02801, PF00698,PF13602,PF14765,PF00107,PF00106,PF00109,PF08240; SMCOG1093:Beta-ketoacyl synthase; antiSMASH:Cluster_1.3; go_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein] synthase activity [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0016740 - transferase activity [Evidence IEA]; go_function: GO:0016746 - transferase activity, transferring acyl groups [Evidence IEA]; go_function: GO:0031177 - phosphopantetheine binding [Evidence IEA]; go_process: GO:0006633 - fatty acid biosynthetic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_10132S COG:S; EggNog:ENOG410PPAI; InterPro:IPR005645,IPR029058; PFAM:PF03959; antiSMASH:Cluster_1.3 AKAW2_10133A COG:S; EggNog:ENOG410PMYD; InterPro:IPR002523; TransMembrane:2 (i298-320o340-362i); antiSMASH:Cluster_1.3; go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0046873 - metal ion transmembrane transporter activity [Evidence IEA]; go_process: GO:0030001 - metal ion transport [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_10134A COG:S; EggNog:ENOG410Q1T6; InterPro:IPR036864,IPR001138; PFAM:PF00172; antiSMASH:Cluster_1.3; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_10135A COG:P; EggNog:ENOG410PKCD; InterPro:IPR006043; PFAM:PF00860; TransMembrane:10 (i99-117o123-139i151-171o191-209i247-280o369-394i406- 427o433-450i457-475o481-498i); antiSMASH:Cluster_1.4; go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_10136A COG:G; EggNog:ENOG410Q1FC; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; SMCOG1106:major facilitator transporter; TransMembrane:12 (i146-172o178-198i210-227o233-255i267-294o300-318i374- 396o408-430i451-472o478-499i511-535o547-569i); antiSMASH:Cluster_1.4; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_10137S COG:S; EggNog:ENOG410PRSA; TransMembrane:8 (i5-22o79-99i111-138o158-180i192-215o235-266i306-323o343- 365i); antiSMASH:Cluster_1.4 AKAW2_10138S COG:S; EggNog:ENOG410PKIP; InterPro:IPR000571; PFAM:PF00642,PF18044; antiSMASH:Cluster_1.4; go_function: GO:0046872 - metal ion binding [Evidence IEA] AKAW2_10139S InterPro:IPR002110,IPR020683,IPR036770; PFAM:PF00023; antiSMASH:Cluster_1.4; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_10140A COG:G; EggNog:ENOG410PN7S; InterPro:IPR023271,IPR022357,IPR000425; PFAM:PF00230; TransMembrane:7 (o223-243i255-276o296-317i354-372o384-402i414-430o436- 459i); go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0015267 - channel activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_10141A COG:S; EggNog:ENOG410PQ0N; InterPro:IPR036291,IPR002347; PFAM:PF00106; TransMembrane:1 (o227-245i); go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_10142S COG:Q; EggNog:ENOG410PH0S; InterPro:IPR017871,IPR027417,IPR003593,IPR011527, IPR003439,IPR036640; PFAM:PF00005,PF00664; TransMembrane:15 (o12-34i75-102o108-126i138-156o168-189i275-299o311- 329i426-445o508-532i893-918o944-970i1023-1043o1049- 1066i1122-1142o1148-1171i); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA]; go_function: GO:0042626 - ATPase-coupled transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_10143S COG:Q; EggNog:ENOG410QECW; InterPro:IPR002347,IPR036291,IPR020904; PFAM:PF00106,PF13561,PF08659; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_10144A COG:S; EggNog:ENOG410PXNS; InterPro:IPR036864,IPR001138; PFAM:PF00172; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_10145A COG:G; EggNog:ENOG410Q1CY; InterPro:IPR013022,IPR036237; PFAM:PF01261 AKAW2_10146A COG:U; EggNog:ENOG410PPK5; TransMembrane:4 (i31-52o64-86i98-115o135-152i) AKAW2_10147A COG:S; EggNog:ENOG410PIWF; InterPro:IPR008979,IPR029058,IPR005674,IPR013736, IPR000383; PFAM:PF02129,PF08530; go_function: GO:0008239 - dipeptidyl-peptidase activity [Evidence IEA]; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_10148S COG:S; EggNog:ENOG410PKBY; InterPro:IPR008775; PFAM:PF05721 AKAW2_10149S COG:S; EggNog:ENOG410QDY8; InterPro:IPR005829,IPR002052,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i61-84o104-123i130-150o156-177i189-207o219-239i316- 339o359-379i400-419o431-455i467-487o499-519i); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0008168 - methyltransferase activity [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0032259 - methylation [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_10150A COG:S; EggNog:ENOG410PT45; InterPro:IPR001810,IPR036047; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_10151S COG:P,Q; EggNog:ENOG410PHSN; InterPro:IPR013112,IPR017927,IPR013130,IPR013121, IPR039261; PFAM:PF08022,PF01794,PF08030; SECRETED:SignalP(1-16); TransMembrane:7 (n2-12c16/17o178-202i271-291o311-337i349-369o384-405i412- 429o441-459i); go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_10152A COG:I; EggNog:ENOG410PP2D; InterPro:IPR019826,IPR002018,IPR029058; MEROPS:MER0030934; PFAM:PF00135; SECRETED:SignalP(1-22) AKAW2_10153A COG:G; EggNog:ENOG410PUJ2; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i64-85o97-120i132-150o156-178i190-213o225-251i298- 321o333-356i377-396o402-421i433-459o471-490i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_10154S COG:S; EggNog:ENOG410PYBY AKAW2_10155S COG:O; EggNog:ENOG410PIXI; InterPro:IPR021109,IPR033876,IPR001461,IPR001969, IPR033121; MEROPS:MER0003669; PFAM:PF00026,PF14543; go_function: GO:0004190 - aspartic-type endopeptidase activity [Evidence IEA]; go_process: GO:0006508 - proteolysis [Evidence IEA] AKAW2_10156A COG:S; EggNog:ENOG410PIJ1; InterPro:IPR017853; SECRETED:SignalP(1-20) AKAW2_10157S CAZy:GH29; COG:G; EggNog:ENOG410PG9E; InterPro:IPR017853,IPR016286,IPR000933; PFAM:PF01120; SECRETED:SignalP(1-18); go_function: GO:0004560 - alpha-L-fucosidase activity [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA]; go_process: GO:0006004 - fucose metabolic process [Evidence IEA] AKAW2_10158A COG:S; EggNog:ENOG410PM6A; InterPro:IPR036864,IPR021858,IPR001138; PFAM:PF11951; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_10159A COG:G; EggNog:ENOG410PIY9; InterPro:IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i56-83o95-117i124-143o155-174i186-204o216-237i286- 310o322-343i350-370o376-399i411-431o443-463i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_10160S COG:E; EggNog:ENOG410PGSZ; InterPro:IPR002821,IPR008040,IPR003692; PFAM:PF01968,PF05378,PF02538; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_10161S COG:S; EggNog:ENOG410PMK6 AKAW2_10162A COG:Q; EggNog:ENOG410PMFG; InterPro:IPR001128,IPR017972,IPR002401,IPR036396; PFAM:PF00067; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_10163A COG:Q; EggNog:ENOG410PWJA; InterPro:IPR008775; PFAM:PF05721 AKAW2_10164S COG:E; EggNog:ENOG410PUZE; InterPro:IPR004841; PFAM:PF13520,PF00324; TransMembrane:11 (o54-73i85-103o136-158i165-185o191-212i278-297o330- 349i378-399o405-430i451-475o487-507i); go_component: GO:0016020 - membrane [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_10165A COG:S; EggNog:ENOG410PGY4; InterPro:IPR000791; PFAM:PF01184; TransMembrane:6 (i88-109o115-134i141-162o182-203i210-231o243-263i); go_component: GO:0016021 - integral component of membrane [Evidence IEA] AKAW2_10166S COG:E; EggNog:ENOG410PI88; InterPro:IPR015889,IPR007535,IPR000627; PFAM:PF04444,PF00775; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0008199 - ferric iron binding [Evidence IEA]; go_function: GO:0016702 - oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [Evidence IEA]; go_function: GO:0018576 - catechol 1,2-dioxygenase activity [Evidence IEA]; go_process: GO:0006725 - cellular aromatic compound metabolic process [Evidence IEA]; go_process: GO:0009712 - catechol-containing compound metabolic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_10167A COG:S; EggNog:ENOG410PW15; InterPro:IPR017441,IPR011009; go_function: GO:0005524 - ATP binding [Evidence IEA] AKAW2_10168A COG:S; EggNog:ENOG410PITV; InterPro:IPR017946; TransMembrane:1 (i101-125o); go_function: GO:0008081 - phosphoric diester hydrolase activity [Evidence IEA]; go_process: GO:0006629 - lipid metabolic process [Evidence IEA] AKAW2_10169A COG:S; EggNog:ENOG410PSXZ; InterPro:IPR029063; PFAM:PF13489,PF08241 AKAW2_10170A COG:T; EggNog:ENOG410PM0V; InterPro:IPR019819,IPR019826,IPR002018,IPR029058; MEROPS:MER0033198; PFAM:PF00135; SECRETED:SignalP(1-16); antiSMASH:Cluster_1.5 AKAW2_10171A COG:S; EggNog:ENOG410Q2MT; TransMembrane:7 (o26-49i61-83o103-126i138-158o178-200i212-235o247-268i); antiSMASH:Cluster_1.5 AKAW2_10172S COG:E; EggNog:ENOG410PV03; InterPro:IPR002293; PFAM:PF00324,PF13520; SMCOG1038:phenylalanine-specific permease; TransMembrane:12 (i58-78o98-119i140-172o184-203i215-234o246-268i289- 317o337-362i394-414o420-444i465-483o495-515i); antiSMASH:Cluster_1.5; go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_10173A COG:S; EggNog:ENOG410PN3H; InterPro:IPR033964,IPR017795,IPR012148; MEROPS:MER0066227; PFAM:PF11991; TransMembrane:1 (o14-34i); antiSMASH:Cluster_1.5; go_function: GO:0016765 - transferase activity, transferring alkyl or aryl (other than methyl) groups [Evidence IEA]; go_process: GO:0009820 - alkaloid metabolic process [Evidence IEA] AKAW2_10174S COG:Q; EggNog:ENOG410PK67; InterPro:IPR020946,IPR036188; PFAM:PF07992,PF13738,PF13450; SMCOG1092:hypothetical protein; antiSMASH:Cluster_1.5; go_function: GO:0004499 - N,N-dimethylaniline monooxygenase activity [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_function: GO:0050661 - NADP binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_10175S COG:S; EggNog:ENOG410PNHN; InterPro:IPR027417; antiSMASH:Cluster_1.5 AKAW2_10176S COG:S; EggNog:ENOG410PJS1; InterPro:IPR000048; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_10177A COG:S; EggNog:ENOG410PZ05; InterPro:IPR036568,IPR009288,IPR013024; PFAM:PF06094 AKAW2_10178S COG:T; EggNog:ENOG410PKZR; InterPro:IPR004813,IPR004648; PFAM:PF03169; TransMembrane:15 (o51-71i78-96o125-145i157-182o188-208i220-239o297-319i372- 395o434-455i462-483o511-528i544-563o610-632i653-678o690- 714i); go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_10179S COG:G; EggNog:ENOG410PMKK; InterPro:IPR041792,IPR008963,IPR039331,IPR025733, IPR003961,IPR004843,IPR014390,IPR015914; PFAM:PF16656,PF00149,PF14008; SECRETED:SignalP(1-20); go_function: GO:0003993 - acid phosphatase activity [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_function: GO:0016787 - hydrolase activity [Evidence IEA]; go_function: GO:0046872 - metal ion binding [Evidence IEA] AKAW2_10182A COG:S; EggNog:ENOG410PYZS AKAW2_10183A COG:S; EggNog:ENOG410Q2QD; InterPro:IPR021858; PFAM:PF11951 AKAW2_10184S COG:Q; EggNog:ENOG410PJKV; InterPro:IPR036291,IPR002347; PFAM:PF08659,PF00106,PF13561; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_10185S COG:G; EggNog:ENOG410PG6S; InterPro:IPR018970,IPR019789,IPR029061,IPR018969, IPR019790,IPR005593,IPR023962,IPR009014; PFAM:PF09364,PF03894,PF09363; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0016832 - aldehyde-lyase activity [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_10186A COG:S; EggNog:ENOG410Q23K; InterPro:IPR036404 AKAW2_10187A COG:S; EggNog:ENOG410Q2DN; TransMembrane:6 (o26-50i57-80o86-108i120-143o163-181i202-227o) AKAW2_10188A CAZy:GH28; COG:G; EggNog:ENOG410PNPK; InterPro:IPR000743,IPR012334,IPR006626,IPR011050; PFAM:PF00295; SECRETED:SignalP(1-18); go_function: GO:0004650 - polygalacturonase activity [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_10189A COG:S; EggNog:ENOG410PIKX; InterPro:IPR012292; PFAM:PF11563; go_function: GO:0019825 - oxygen binding [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA] AKAW2_10190S COG:S; EggNog:ENOG410Q2Y6 AKAW2_10191A COG:G; EggNog:ENOG410PVSU; InterPro:IPR020846,IPR005828,IPR036259; TransMembrane:5 (o69-92i99-121o127-146i167-187o193-214i); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_10192A COG:G; EggNog:ENOG410PVSU; InterPro:IPR005829,IPR005828,IPR020846,IPR036259, IPR003663; TransMembrane:6 (i12-30o60-79i86-106o112-132i144-162o182-202i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_10193A CAZy:GH11; COG:G; EggNog:ENOG410PK7J; InterPro:IPR001137,IPR013319,IPR013320,IPR033123, IPR018208; PFAM:PF00457; SECRETED:SignalP(1-19); go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_10194A COG:Q; EggNog:ENOG410PUVH; InterPro:IPR013154,IPR013149,IPR036291,IPR011032, IPR020843; PFAM:PF00107,PF08240; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_10195S COG:S; EggNog:ENOG410PSHX; InterPro:IPR018392,IPR036779; PFAM:PF01476; SECRETED:SignalP(1-19) AKAW2_10196S COG:E; EggNog:ENOG410PHQD; InterPro:IPR000132,IPR036526,IPR037544,IPR044149, IPR003010; PFAM:PF00795; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0030196 - cyanide hydratase activity [Evidence IEA]; go_process: GO:0006807 - nitrogen compound metabolic process [Evidence IEA]; go_process: GO:0019500 - cyanide catabolic process [Evidence IEA] AKAW2_10197S COG:S; EggNog:ENOG410Q1U5; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; TransMembrane:1 (o587-607i); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_10198S COG:C; EggNog:ENOG410PKHE; InterPro:IPR012133,IPR037396,IPR008259,IPR013785, IPR000262; PFAM:PF01070; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0010181 - FMN binding [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_10199A CAZy:AA7; COG:C; EggNog:ENOG410PKT2; InterPro:IPR006094,IPR036318,IPR016166,IPR012951; PFAM:PF08031,PF01565; SECRETED:SignalP(1-21); go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_function: GO:0071949 - FAD binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_10200A COG:I; EggNog:ENOG410PG8S; InterPro:IPR011074,IPR036865,IPR036273,IPR001251; PFAM:PF00650,PF03765,PF13716 AKAW2_10201S COG:Q; EggNog:ENOG410PI5X; InterPro:IPR001128,IPR017972,IPR002401,IPR036396; PFAM:PF00067; TransMembrane:2 (i7-26o38-57i); go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_10202S COG:M,P,T; EggNog:ENOG410PUCJ; InterPro:IPR002110,IPR036770,IPR020683; PFAM:PF13857,PF12796,PF00023,PF13637,PF13606; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_10203S COG:U; EggNog:ENOG410QE2Y; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:14 (i73-92o126-145i157-180o186-205i217-239o245-266i278- 297o309-327i347-369o381-405i412-431o437-462i474-494o514- 533i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_10204S COG:G; EggNog:ENOG410PFF2; InterPro:IPR020846,IPR001958,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i49-69o84-104i116-133o139-162i174-192o204-224i283- 305o317-336i376-394o406-427i439-460o466-489i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_10205S SECRETED:SignalP(1-24) AKAW2_10206S COG:S; EggNog:ENOG410PSF9; InterPro:IPR011008,IPR009799; PFAM:PF07110; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA] AKAW2_10207S COG:T; EggNog:ENOG410PWBG; InterPro:IPR000719,IPR011009,IPR017441; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_10208S COG:T; EggNog:ENOG410PWBG; InterPro:IPR011009 AKAW2_10209A COG:I; EggNog:ENOG410PPMM; InterPro:IPR000073,IPR029058,IPR000639; MEROPS:MER0017177; PFAM:PF12697; go_function: GO:0003824 - catalytic activity [Evidence IEA] AKAW2_10210A COG:S; EggNog:ENOG410PX5S; InterPro:IPR036610,IPR008914,IPR035810; PFAM:PF01161; SECRETED:SignalP(1-16) AKAW2_10212A COG:S; EggNog:ENOG410PUSJ AKAW2_10213A COG:F; EggNog:ENOG410PMUR; InterPro:IPR036322,IPR015943,IPR011047,IPR001680, IPR017986; PFAM:PF00400; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_10214A COG:F; EggNog:ENOG410PMUR; InterPro:IPR029058 AKAW2_10215S COG:G; EggNog:ENOG410PWKY; InterPro:IPR016477,IPR011009; PFAM:PF03881 AKAW2_10216A COG:S; EggNog:ENOG410PIBV; InterPro:IPR036864,IPR021858,IPR001138; PFAM:PF00172; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_10218A COG:U,Y; EggNog:ENOG410PJ5B; InterPro:IPR016024,IPR011989,IPR040122; PFAM:PF02985,PF13513; go_process: GO:0006606 - protein import into nucleus [Evidence IEA] AKAW2_10219A COG:I; EggNog:ENOG410PGTK; InterPro:IPR034753,IPR022158,IPR002013; PFAM:PF02383,PF12456; SECRETED:SignalP(1-16); go_function: GO:0042578 - phosphoric ester hydrolase activity [Evidence IEA] AKAW2_10220A COG:S; EggNog:ENOG410PFV6; InterPro:IPR008521; PFAM:PF05653; TransMembrane:9 (o6-26i51-72o78-97i104-123o135-160i172-194o206-223i244- 261o273-291i); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0015095 - magnesium ion transmembrane transporter activity [Evidence IEA]; go_process: GO:0015693 - magnesium ion transport [Evidence IEA] AKAW2_10221A COG:S; EggNog:ENOG410PTTB; InterPro:IPR018822; PFAM:PF10336 AKAW2_10222S BUSCO:EOG09264V3H; COG:U; EggNog:ENOG410PFIY; InterPro:IPR022775,IPR027059,IPR011012,IPR036168, IPR028565; PFAM:PF00928,PF01217; go_component: GO:0030126 - COPI vesicle coat [Evidence IEA]; go_process: GO:0006890 - retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [Evidence IEA] AKAW2_10223A COG:S; EggNog:ENOG410PKT9 AKAW2_10224A COG:S; EggNog:ENOG410PVKY; InterPro:IPR013785,IPR001754; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0004590 - orotidine-5'-phosphate decarboxylase activity [Evidence IEA]; go_process: GO:0006207 - 'de novo' pyrimidine nucleobase biosynthetic process [Evidence IEA] AKAW2_10225S BUSCO:EOG09263KDI; COG:I; EggNog:ENOG410PH7M; InterPro:IPR001199,IPR014430,IPR036400,IPR018506, IPR006694; PFAM:PF00173,PF04116; TransMembrane:4 (i184-208o214-231i269-287o293-312i); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_function: GO:0080132 - fatty acid alpha-hydroxylase activity [Evidence IEA]; go_process: GO:0006629 - lipid metabolic process [Evidence IEA]; go_process: GO:0008610 - lipid biosynthetic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_10226S COG:A; EggNog:ENOG410PI0I; InterPro:IPR000504,IPR035979,IPR012677,IPR029123, IPR006509; PFAM:PF15519,PF00076; go_component: GO:0005634 - nucleus [Evidence IEA]; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0003723 - RNA binding [Evidence IEA]; go_process: GO:0006397 - mRNA processing [Evidence IEA] AKAW2_10227S BUSCO:EOG09261KRX; COG:T; EggNog:ENOG410PFGC; InterPro:IPR000222,IPR036457,IPR001932,IPR015655; PFAM:PF00481; go_function: GO:0004722 - protein serine/threonine phosphatase activity [Evidence IEA]; go_function: GO:0016791 - phosphatase activity [Evidence IEA]; go_function: GO:0043169 - cation binding [Evidence IEA]; go_process: GO:0006470 - protein dephosphorylation [Evidence IEA] AKAW2_10228S BUSCO:EOG09264CP8; COG:I; EggNog:ENOG410PI51; InterPro:IPR000462,IPR043130; PFAM:PF01066; TransMembrane:2 (i183-203o238-257i); go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0016780 - phosphotransferase activity, for other substituted phosphate groups [Evidence IEA]; go_process: GO:0008654 - phospholipid biosynthetic process [Evidence IEA] AKAW2_10229S COG:E; EggNog:ENOG410PFHG; InterPro:IPR019818,IPR024084,IPR004429; PFAM:PF00180; go_function: GO:0000287 - magnesium ion binding [Evidence IEA]; go_function: GO:0003862 - 3-isopropylmalate dehydrogenase activity [Evidence IEA]; go_function: GO:0016616 - oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Evidence IEA]; go_function: GO:0051287 - NAD binding [Evidence IEA]; go_process: GO:0009098 - leucine biosynthetic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_10230A BUSCO:EOG09265DVA; COG:D; EggNog:ENOG410PPMA; InterPro:IPR004939,IPR016901,IPR008979; PFAM:PF03256; go_component: GO:0005680 - anaphase-promoting complex [Evidence IEA]; go_process: GO:0031145 - anaphase-promoting complex-dependent catabolic process [Evidence IEA] AKAW2_10231A BUSCO:EOG092639H5; COG:I; EggNog:ENOG410PFVD; InterPro:IPR003817,IPR033661,IPR033177; PFAM:PF02666; TransMembrane:1 (o82-100i); go_component: GO:0005739 - mitochondrion [Evidence IEA]; go_function: GO:0004609 - phosphatidylserine decarboxylase activity [Evidence IEA]; go_process: GO:0008654 - phospholipid biosynthetic process [Evidence IEA] AKAW2_10232S COG:S; EggNog:ENOG410PMIN; InterPro:IPR039751,IPR000626,IPR029071; PFAM:PF00240; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_10233A COG:G; EggNog:ENOG410PMU8; InterPro:IPR013078,IPR029033 AKAW2_10234A COG:J; EggNog:ENOG410PNSS; InterPro:IPR035987,IPR000630; PFAM:PF00410; go_component: GO:0005840 - ribosome [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_process: GO:0006412 - translation [Evidence IEA] AKAW2_10235A BUSCO:EOG09260HMA; COG:U,Y; EggNog:ENOG410PFHH; InterPro:IPR016024,IPR011989,IPR021133,IPR040122, IPR001494; PFAM:PF02985,PF03810,PF13513; go_function: GO:0008536 - Ran GTPase binding [Evidence IEA]; go_process: GO:0006606 - protein import into nucleus [Evidence IEA]; go_process: GO:0006886 - intracellular protein transport [Evidence IEA] AKAW2_10236A COG:D; EggNog:ENOG410PIQN; InterPro:IPR024790,IPR024977,IPR024789,IPR036322, IPR015943; PFAM:PF12894,PF12896; go_component: GO:0005680 - anaphase-promoting complex [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0030071 - regulation of mitotic metaphase/anaphase transition [Evidence IEA]; go_process: GO:0031145 - anaphase-promoting complex-dependent catabolic process [Evidence IEA] AKAW2_10237A COG:S; EggNog:ENOG410PW5S AKAW2_10238A COG:S; EggNog:ENOG410Q1PY; InterPro:IPR036465,IPR002035 AKAW2_10239A COG:S; EggNog:ENOG410PWIG; InterPro:IPR036864,IPR021858,IPR001138; PFAM:PF00172,PF11951; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_10240A CAZy:AA1; COG:Q; EggNog:ENOG410PJMK; InterPro:IPR008972,IPR011707,IPR011706,IPR033138, IPR002355,IPR001117; PFAM:PF00394,PF07731,PF07732; SECRETED:SignalP(1-23); go_function: GO:0005507 - copper ion binding [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_10241A COG:Q; EggNog:ENOG410PNXK; InterPro:IPR036291,IPR002347; PFAM:PF00106,PF13561; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_10244A COG:S; EggNog:ENOG410PNQZ; InterPro:IPR011057 AKAW2_10245S COG:K; EggNog:ENOG410PRHB; InterPro:IPR011598,IPR036638; PFAM:PF00010; go_function: GO:0046983 - protein dimerization activity [Evidence IEA] AKAW2_10246S BUSCO:EOG092643IE; COG:D; EggNog:ENOG410PJZR; InterPro:IPR029001,IPR003697; PFAM:PF02545; go_function: GO:0047429 - nucleoside-triphosphate diphosphatase activity [Evidence IEA] AKAW2_10247A COG:C; EggNog:ENOG410PNQN; InterPro:IPR034804,IPR007992; PFAM:PF05328; go_component: GO:0005740 - mitochondrial envelope [Evidence IEA]; go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA] AKAW2_10248A COG:F; EggNog:ENOG410PFCH; InterPro:IPR001114,IPR027417,IPR042110,IPR042111, IPR033128,IPR018220,IPR042109; PFAM:PF00709; go_function: GO:0004019 - adenylosuccinate synthase activity [Evidence IEA]; go_function: GO:0005525 - GTP binding [Evidence IEA]; go_process: GO:0006164 - purine nucleotide biosynthetic process [Evidence IEA] AKAW2_10249A COG:O; EggNog:ENOG410QDQN; InterPro:IPR001623,IPR036869,IPR018253; PFAM:PF00226 AKAW2_10250A COG:K; EggNog:ENOG410PHRG; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; TransMembrane:3 (i355-371o436-457i733-756o); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_10251A COG:G; EggNog:ENOG410PH2P; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i28-50o65-87i99-118o124-148i160-181o201-223i320-340o376- 395i407-426o438-461i468-486o506-524i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_10253S COG:B,T; EggNog:ENOG410PH3Q; InterPro:IPR036726,IPR006073,IPR027417,IPR006169, IPR031167; PFAM:PF01018,PF01926; go_function: GO:0005525 - GTP binding [Evidence IEA] AKAW2_10254S COG:B,T; EggNog:ENOG410PI7T; InterPro:IPR041667,IPR003347; PFAM:PF13621 AKAW2_10255S COG:K; EggNog:ENOG410PFTN; InterPro:IPR008422,IPR001356,IPR013087,IPR009057; PFAM:PF05920; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_10256S COG:S; EggNog:ENOG410PR2Y; TransMembrane:1 (o255-278i) AKAW2_10257S COG:O; EggNog:ENOG410PIZU; InterPro:IPR016135,IPR000608; PFAM:PF00179 AKAW2_10258S TransMembrane:1 (o12-34i) AKAW2_10259A COG:S; EggNog:ENOG410PK17; InterPro:IPR005123,IPR003892,IPR010666,IPR032854, IPR027450,IPR037151; PFAM:PF06839,PF13532; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0043130 - ubiquitin binding [Evidence IEA]; go_function: GO:0051213 - dioxygenase activity [Evidence IEA]; go_process: GO:0006281 - DNA repair [Evidence IEA]; go_process: GO:0006307 - DNA dealkylation involved in DNA repair [Evidence IEA]; go_process: GO:0035552 - oxidative single-stranded DNA demethylation [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_10260S COG:Q; EggNog:ENOG410PW8M; InterPro:IPR036188; PFAM:PF07992,PF13738 AKAW2_10261A COG:S; EggNog:ENOG410Q2KG AKAW2_10262S COG:K; EggNog:ENOG410PMKE; InterPro:IPR036236,IPR027417,IPR029058,IPR007111, IPR013087; PFAM:PF05729,PF00096 AKAW2_10263A COG:L; EggNog:ENOG410PIVK; InterPro:IPR038718,IPR000330,IPR027417,IPR014001, IPR001650; PFAM:PF00176,PF00271; go_function: GO:0005524 - ATP binding [Evidence IEA] AKAW2_10264A COG:L; EggNog:ENOG410PIVK AKAW2_10265A COG:S; EggNog:ENOG410PI3H; TransMembrane:4 (o142-161i237-257o269-287i308-337o) AKAW2_10266S BUSCO:EOG09262VOC; COG:U; EggNog:ENOG410PG5J; InterPro:IPR036322,IPR015943,IPR019775,IPR001680, IPR017986; PFAM:PF00400; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_10267A COG:S; EggNog:ENOG410PGCR; InterPro:IPR010422; PFAM:PF06244 AKAW2_10268A COG:S; EggNog:ENOG410PM71; InterPro:IPR001810,IPR036047; PFAM:PF00646,PF12937; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_10269A CAZy:AA1; COG:Q; EggNog:ENOG410PJMK; InterPro:IPR008972,IPR011707,IPR011706,IPR033138, IPR002355,IPR001117; PFAM:PF00394,PF07731,PF07732; SECRETED:SignalP(1-21); go_function: GO:0005507 - copper ion binding [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_10270A COG:S; EggNog:ENOG410PQXD; TransMembrane:1 (o500-517i) AKAW2_10271A COG:K; EggNog:ENOG410PHAZ; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_10272A COG:S; EggNog:ENOG410PHJP; InterPro:IPR012349,IPR002563; PFAM:PF01613; go_function: GO:0010181 - FMN binding [Evidence IEA] AKAW2_10273S COG:Q; EggNog:ENOG410Q2GV; InterPro:IPR014049,IPR004887,IPR037013,IPR016185, IPR014042,IPR014709,IPR005615; PFAM:PF03917,PF03199; TransMembrane:1 (o90-110i); go_function: GO:0004363 - glutathione synthase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016874 - ligase activity [Evidence IEA]; go_process: GO:0006750 - glutathione biosynthetic process [Evidence IEA] AKAW2_10274A CAZy:GH13; COG:G; EggNog:ENOG410PINX; InterPro:IPR006047,IPR015237,IPR017853,IPR013780, IPR013776; PFAM:PF00128,PF09154; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_function: GO:0005509 - calcium ion binding [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_10275S COG:C; EggNog:ENOG410PFA1; InterPro:IPR018108,IPR023395,IPR002067; PFAM:PF00153; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_10276A COG:S; EggNog:ENOG410Q2JW; TransMembrane:4 (i70-91o111-132i144-163o183-202i) AKAW2_10277A COG:E; EggNog:ENOG410PH1F; InterPro:IPR032095,IPR036291,IPR005097; PFAM:PF03435,PF01488,PF16653; SECRETED:SignalP(1-25); go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_10278S COG:E; EggNog:ENOG410PHFQ; InterPro:IPR000073,IPR008220,IPR029058; PFAM:PF00561; go_function: GO:0016747 - transferase activity, transferring acyl groups other than amino-acyl groups [Evidence IEA]; go_process: GO:0009058 - biosynthetic process [Evidence IEA] AKAW2_10279S BUSCO:EOG09260VYK; COG:A; EggNog:ENOG410PIVC; InterPro:IPR014492,IPR002934,IPR007012,IPR011068, IPR007010,IPR043519; PFAM:PF04928,PF04926,PF01909; go_component: GO:0005634 - nucleus [Evidence IEA]; go_function: GO:0003723 - RNA binding [Evidence IEA]; go_function: GO:0004652 - polynucleotide adenylyltransferase activity [Evidence IEA]; go_function: GO:0016779 - nucleotidyltransferase activity [Evidence IEA]; go_process: GO:0031123 - RNA 3'-end processing [Evidence IEA]; go_process: GO:0043631 - RNA polyadenylation [Evidence IEA] AKAW2_10280A COG:S; EggNog:ENOG410QDK1; InterPro:IPR042213,IPR010737,IPR037051,IPR031475; PFAM:PF17042,PF07005 AKAW2_10281A BUSCO:EOG0926129I; COG:L; EggNog:ENOG410PX24; InterPro:IPR003874; PFAM:PF02724; TransMembrane:1 (o722-742i); go_process: GO:0006270 - DNA replication initiation [Evidence IEA] AKAW2_10282A BUSCO:EOG09262M0W; COG:O; EggNog:ENOG410PFK5; InterPro:IPR028361,IPR001096; MEROPS:MER0002477; PFAM:PF01650; SECRETED:SignalP(1-25); go_component: GO:0042765 - GPI-anchor transamidase complex [Evidence IEA]; go_function: GO:0003923 - GPI-anchor transamidase activity [Evidence IEA]; go_function: GO:0008233 - peptidase activity [Evidence IEA]; go_process: GO:0006508 - proteolysis [Evidence IEA]; go_process: GO:0016255 - attachment of GPI anchor to protein [Evidence IEA] AKAW2_10283A CAZy:AA3; COG:E; EggNog:ENOG410PG0A; InterPro:IPR007867,IPR000172,IPR036188,IPR029058; PFAM:PF00732; go_function: GO:0016614 - oxidoreductase activity, acting on CH-OH group of donors [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_10284S COG:S; EggNog:ENOG410PNYM; InterPro:IPR029058; TransMembrane:3 (o138-162i183-205o211-229i) AKAW2_10285S COG:I; EggNog:ENOG410PHJJ; InterPro:IPR003703,IPR029069; PFAM:PF13622,PF02551; go_function: GO:0047617 - acyl-CoA hydrolase activity [Evidence IEA]; go_process: GO:0006637 - acyl-CoA metabolic process [Evidence IEA] AKAW2_10286A COG:S; EggNog:ENOG410PWEF; InterPro:IPR021848; PFAM:PF11927 AKAW2_10287S COG:S; EggNog:ENOG410PNTG; InterPro:IPR036691 AKAW2_10288A COG:O; EggNog:ENOG410PH37; InterPro:IPR013126,IPR043129 AKAW2_10289A COG:G; EggNog:ENOG410PHDA; InterPro:IPR012901,IPR029063; PFAM:PF07942 AKAW2_10290S COG:S; EggNog:ENOG410PQM8; InterPro:IPR032157; PFAM:PF16093; go_process: GO:0043248 - proteasome assembly [Evidence IEA] AKAW2_10292S COG:K; EggNog:ENOG410PJXA; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_10293A COG:O; EggNog:ENOG410PPVD; InterPro:IPR009053,IPR016661,IPR002777; PFAM:PF01920; go_component: GO:0016272 - prefoldin complex [Evidence IEA]; go_function: GO:0051082 - unfolded protein binding [Evidence IEA]; go_process: GO:0006457 - protein folding [Evidence IEA] AKAW2_10294S COG:S; EggNog:ENOG410PKXN; InterPro:IPR018939; PFAM:PF09451; SECRETED:SignalP(1-23); TransMembrane:1 (n6-17c23/24o269-291i) AKAW2_10295A COG:S; EggNog:ENOG410PH3C; InterPro:IPR027417 AKAW2_10296S COG:O; EggNog:ENOG410PGGQ; InterPro:IPR028299,IPR003959,IPR003593,IPR004176, IPR027417,IPR041546,IPR019489,IPR018368,IPR036628, IPR001270; PFAM:PF10431,PF00004,PF17871,PF07724,PF02861, PF00158,PF07728; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA] AKAW2_10297A CAZy:CE4; COG:Q; EggNog:ENOG410Q18D; InterPro:IPR002509,IPR037950,IPR011330,IPR036291, IPR002347; PFAM:PF00106,PF13561,PF01522; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0016810 - hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_10298A COG:S; EggNog:ENOG410PMVQ; TransMembrane:7 (o23-42i54-75o112-130i142-166o186-206i218-236o256-275i) AKAW2_10299S COG:E; EggNog:ENOG410PJE6; InterPro:IPR002293,IPR004840; PFAM:PF13520,PF00324; TransMembrane:12 (i38-57o77-97i118-142o162-182i194-214o234-255i276-299o328- 350i380-400o406-425i446-469o475-496i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0006865 - amino acid transport [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_10300S COG:L; EggNog:ENOG410PG5P; InterPro:IPR038718,IPR000330,IPR027417,IPR014001, IPR001650; PFAM:PF00176,PF00271,PF04851; go_function: GO:0005524 - ATP binding [Evidence IEA] AKAW2_10301A COG:O; EggNog:ENOG410PFF0 AKAW2_10302A COG:I; EggNog:ENOG410PN3B; InterPro:IPR033118,IPR007905; PFAM:PF05241; TransMembrane:5 (o30-53i65-86o117-139i151-169o189-209i); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0047750 - cholestenol delta-isomerase activity [Evidence IEA]; go_process: GO:0016125 - sterol metabolic process [Evidence IEA] AKAW2_10303S BUSCO:EOG09263A3Y; COG:S; EggNog:ENOG410PI99; InterPro:IPR028115,IPR018626; PFAM:PF09804,PF14831 AKAW2_10304A COG:S; EggNog:ENOG410PSKN AKAW2_10305S BUSCO:EOG09261N20; COG:Z; EggNog:ENOG410PIW0; InterPro:IPR019605,IPR029209,IPR036525; PFAM:PF14881,PF10644 AKAW2_10306S BUSCO:EOG09260JPV; COG:O; EggNog:ENOG410PFF0; InterPro:IPR013126,IPR029047,IPR029048,IPR043129; PFAM:PF00012; SECRETED:SignalP(1-38); TransMembrane:1 (i33-55o); antiSMASH:Cluster_1.6 AKAW2_10307A COG:S; EggNog:ENOG410PRXE; InterPro:IPR013900; antiSMASH:Cluster_1.6 AKAW2_10308A BUSCO:EOG09260TLW; COG:D,Z; EggNog:ENOG410PFF6; InterPro:IPR012977,IPR027312,IPR016024,IPR007949; PFAM:PF05285,PF08158; antiSMASH:Cluster_1.6; go_process: GO:0000055 - ribosomal large subunit export from nucleus [Evidence IEA]; go_process: GO:0030036 - actin cytoskeleton organization [Evidence IEA]; go_process: GO:0042273 - ribosomal large subunit biogenesis [Evidence IEA] AKAW2_10309A COG:J; EggNog:ENOG410PIAI; InterPro:IPR020606,IPR036823,IPR000235,IPR023798, IPR005716; PFAM:PF00177; antiSMASH:Cluster_1.6; go_component: GO:0015935 - small ribosomal subunit [Evidence IEA]; go_function: GO:0003723 - RNA binding [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_process: GO:0006412 - translation [Evidence IEA] AKAW2_10310S COG:I,Q; EggNog:ENOG410PI0R; InterPro:IPR042099,IPR010506,IPR000873,IPR037337; PFAM:PF00501; SMCOG1002:AMP-dependent synthetase and ligase; TransMembrane:1 (i350-370o); antiSMASH:Cluster_1.6 AKAW2_10311A COG:E; EggNog:ENOG410PGJG; InterPro:IPR036230,IPR002034,IPR000891,IPR013709, IPR005668,IPR013785,IPR039371; PFAM:PF00682,PF08502; SMCOG1271:2-isopropylmalate synthase; antiSMASH:Cluster_1.6; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0003852 - 2-isopropylmalate synthase activity [Evidence IEA]; go_function: GO:0046912 - transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer [Evidence IEA]; go_process: GO:0009098 - leucine biosynthetic process [Evidence IEA]; go_process: GO:0019752 - carboxylic acid metabolic process [Evidence IEA] AKAW2_10312A COG:A; EggNog:ENOG410PH8K; InterPro:IPR027417,IPR001650,IPR014014,IPR014001, IPR011545,IPR000629; PFAM:PF00270,PF00271; SMCOG1122:ATP-dependent RNA helicase; antiSMASH:Cluster_1.6; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0004386 - helicase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA] AKAW2_10313A COG:S; EggNog:ENOG410PT52; InterPro:IPR000182,IPR016181; PFAM:PF00583; antiSMASH:Cluster_1.6; go_function: GO:0008080 - N-acetyltransferase activity [Evidence IEA] AKAW2_10314S BUSCO:EOG09264RJ7; COG:U; EggNog:ENOG410Q7WP; InterPro:IPR005225,IPR027417,IPR006689; PFAM:PF00025,PF08477,PF00071,PF01926; antiSMASH:Cluster_1.6; go_function: GO:0005525 - GTP binding [Evidence IEA] AKAW2_10315S COG:S; EggNog:ENOG410PG87; InterPro:IPR025118,IPR007122,IPR029919,IPR029006; PFAM:PF13254; antiSMASH:Cluster_1.6; go_function: GO:0051015 - actin filament binding [Evidence IEA]; go_process: GO:0030036 - actin cytoskeleton organization [Evidence IEA]; go_process: GO:0051014 - actin filament severing [Evidence IEA] AKAW2_10316A TransMembrane:1 (i94-114o) AKAW2_10317S SECRETED:SignalP(1-44); TransMembrane:2 (n27-39c44/45o54-71i83-101o) AKAW2_10318S COG:K; EggNog:ENOG410PXAE; InterPro:IPR036864,IPR001138; PFAM:PF00172; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_10319A COG:O; EggNog:ENOG410PFF7; InterPro:IPR014756,IPR004179,IPR001623,IPR036869, IPR035892,IPR027137; PFAM:PF00226,PF02889; TransMembrane:3 (o12-34i73-94o205-225i); go_process: GO:0031204 - posttranslational protein targeting to membrane, translocation [Evidence IEA] AKAW2_10320A COG:S; EggNog:ENOG410PZJE AKAW2_10322A COG:E; EggNog:ENOG410PIZA; InterPro:IPR000994,IPR029149,IPR001131,IPR036005, IPR007865; MEROPS:MER0001733; PFAM:PF05195,PF00557; go_function: GO:0030145 - manganese ion binding [Evidence IEA]; go_function: GO:0070006 - metalloaminopeptidase activity [Evidence IEA] AKAW2_10323S COG:S; EggNog:ENOG410PHKF; InterPro:IPR035780,IPR043136,IPR013320,IPR001870, IPR003877; PFAM:PF00622; TransMembrane:1 (o74-98i); go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_10324S BUSCO:EOG092620FM; COG:T; EggNog:ENOG410PFC9; InterPro:IPR000396,IPR036866; go_function: GO:0004115 - 3',5'-cyclic-AMP phosphodiesterase activity [Evidence IEA]; go_process: GO:0006198 - cAMP catabolic process [Evidence IEA] AKAW2_10325A COG:J; EggNog:ENOG410PJW5; InterPro:IPR023631,IPR036928,IPR000120,IPR020556; PFAM:PF01425; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_10326A BUSCO:EOG09264FWI; COG:G; EggNog:ENOG410PH5V; InterPro:IPR009447; PFAM:PF06423; TransMembrane:13 (o20-41i53-73o79-96i136-154o166-185i205-225o240-258i270- 288o308-326i347-367o387-410i440-459o465-487i); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0016746 - transferase activity, transferring acyl groups [Evidence IEA]; go_process: GO:0006506 - GPI anchor biosynthetic process [Evidence IEA] AKAW2_10327A TransMembrane:1 (i21-42o) AKAW2_10329S COG:K; EggNog:ENOG410PY65 AKAW2_10330A SECRETED:SignalP(1-22); TransMembrane:1 (o97-116i) AKAW2_10331A COG:I; EggNog:ENOG410PGSK; InterPro:IPR006091,IPR006089,IPR009075,IPR013786, IPR009100,IPR036250,IPR037069; PFAM:PF02770,PF00441,PF02771,PF08028; go_function: GO:0003995 - acyl-CoA dehydrogenase activity [Evidence IEA]; go_function: GO:0016627 - oxidoreductase activity, acting on the CH-CH group of donors [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_10333A COG:S; EggNog:ENOG410PW9T; InterPro:IPR004843,IPR029052; PFAM:PF00149; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_10332S COG:S; EggNog:ENOG410PGAK; InterPro:IPR009686; PFAM:PF06911 AKAW2_10334S COG:T; EggNog:ENOG410PHT0; InterPro:IPR017441,IPR008271,IPR000719,IPR011009; PFAM:PF07714,PF00069; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_10337S COG:U; EggNog:ENOG410PI4S; InterPro:IPR027532,IPR031468,IPR019411; go_component: GO:0032865 - ERMES complex [Evidence IEA]; go_function: GO:0008289 - lipid binding [Evidence IEA]; go_process: GO:0007005 - mitochondrion organization [Evidence IEA]; go_process: GO:0045040 - protein insertion into mitochondrial outer membrane [Evidence IEA] AKAW2_10339A BUSCO:EOG09264XKX; COG:V; EggNog:ENOG410PH90; InterPro:IPR040463,IPR008417,IPR041672; PFAM:PF18035,PF05529; TransMembrane:3 (o6-28i49-70o108-126i); go_component: GO:0005783 - endoplasmic reticulum [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_process: GO:0006886 - intracellular protein transport [Evidence IEA] AKAW2_10340A BUSCO:EOG09261ZPW; COG:J; EggNog:ENOG410PFC8; InterPro:IPR018517,IPR035587,IPR000571,IPR013785, IPR001269; PFAM:PF01207; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0017150 - tRNA dihydrouridine synthase activity [Evidence IEA]; go_function: GO:0046872 - metal ion binding [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_process: GO:0008033 - tRNA processing [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_10341S COG:K; EggNog:ENOG410PI5F; InterPro:IPR036236,IPR013087 AKAW2_10342A BUSCO:EOG092651HW; COG:K; EggNog:ENOG410QDKB; InterPro:IPR004855,IPR009088; PFAM:PF03153; go_component: GO:0005672 - transcription factor TFIIA complex [Evidence IEA]; go_process: GO:0006367 - transcription initiation from RNA polymerase II promoter [Evidence IEA] AKAW2_10343S COG:S; EggNog:ENOG410PWDN; InterPro:IPR036864,IPR001138; PFAM:PF00172; TransMembrane:1 (i233-251o); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_10344A COG:D; EggNog:ENOG410PIDR; InterPro:IPR024977,IPR036322,IPR015943,IPR019775, IPR001680,IPR033010,IPR017986; PFAM:PF12894,PF00400; go_function: GO:0005515 - protein binding [Evidence IEA]; go_function: GO:0010997 - anaphase-promoting complex binding [Evidence IEA]; go_function: GO:0097027 - ubiquitin-protein transferase activator activity [Evidence IEA]; go_process: GO:1904668 - positive regulation of ubiquitin protein ligase activity [Evidence IEA] AKAW2_10345S COG:S; EggNog:ENOG410PIC0; InterPro:IPR000210,IPR015915,IPR011333,IPR006652; PFAM:PF13418,PF01344,PF00651,PF13415,PF07646, PF13854; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_10346A COG:L; EggNog:ENOG410PRV7 AKAW2_10347A COG:O; EggNog:ENOG410PFCT; InterPro:IPR011990,IPR006597; PFAM:PF08238; SECRETED:SignalP(1-21); TransMembrane:1 (n9-17c21/22o766-785i); go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_10348A COG:K; EggNog:ENOG410PGUD; InterPro:IPR007066,IPR000684,IPR007073,IPR007075, IPR038593,IPR007081,IPR007080,IPR007083,IPR038120, IPR000722,IPR042102,IPR006592; PFAM:PF05000,PF04998,PF05001,PF04997,PF04992, PF04983,PF04990,PF00623; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0003899 - DNA-directed 5'-3' RNA polymerase activity [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006366 - transcription by RNA polymerase II [Evidence IEA] AKAW2_10349S BUSCO:EOG09262XRU; COG:S; EggNog:ENOG410PF85; InterPro:IPR037850,IPR036322,IPR015943,IPR019775, IPR001680,IPR017986; PFAM:PF00400; go_component: GO:0048188 - Set1C/COMPASS complex [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_10350A COG:S; EggNog:ENOG410PNGW; InterPro:IPR029063; PFAM:PF13489 AKAW2_10351S COG:S; EggNog:ENOG410PS85 AKAW2_10352A BUSCO:EOG09264G0H; COG:S; EggNog:ENOG410PGHR; InterPro:IPR024956,IPR038469,IPR007537,IPR025845; PFAM:PF14413,PF04446; go_function: GO:0000287 - magnesium ion binding [Evidence IEA]; go_function: GO:0008193 - tRNA guanylyltransferase activity [Evidence IEA]; go_process: GO:0006400 - tRNA modification [Evidence IEA] AKAW2_10353A COG:S; EggNog:ENOG410PISW; InterPro:IPR013783,IPR036116,IPR003961; TransMembrane:1 (i21-42o); go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_10354S BUSCO:EOG092636Y6; COG:I,N; EggNog:ENOG410Q74I; InterPro:IPR031315,IPR007651,IPR036412,IPR026058, IPR013209; PFAM:PF08235,PF04571 AKAW2_10355S BUSCO:EOG092650VI; COG:K; EggNog:ENOG410PP2X; InterPro:IPR009072,IPR003162; PFAM:PF02291; go_function: GO:0046982 - protein heterodimerization activity [Evidence IEA]; go_process: GO:0006352 - DNA-templated transcription, initiation [Evidence IEA] AKAW2_10356A COG:S; EggNog:ENOG410PRXN; InterPro:IPR013892; PFAM:PF08583 AKAW2_10358S BUSCO:EOG09264CA0; COG:S; EggNog:ENOG410PJ5P; InterPro:IPR007144; PFAM:PF03998; go_component: GO:0032040 - small-subunit processome [Evidence IEA]; go_process: GO:0006364 - rRNA processing [Evidence IEA] AKAW2_10357A BUSCO:EOG09262E98; COG:E; EggNog:ENOG410PJJQ; InterPro:IPR012131,IPR038019,IPR008179,IPR001692, IPR002496,IPR016161,IPR016298,IPR021130; PFAM:PF00815,PF01502,PF01503; go_function: GO:0004399 - histidinol dehydrogenase activity [Evidence IEA]; go_function: GO:0004635 - phosphoribosyl-AMP cyclohydrolase activity [Evidence IEA]; go_function: GO:0004636 - phosphoribosyl-ATP diphosphatase activity [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0016616 - oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Evidence IEA]; go_function: GO:0046872 - metal ion binding [Evidence IEA]; go_function: GO:0051287 - NAD binding [Evidence IEA]; go_process: GO:0000105 - histidine biosynthetic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_10359S CAZy:GH47; COG:G; EggNog:ENOG410PM8H; InterPro:IPR036026,IPR012341,IPR001382; PFAM:PF01532; SECRETED:SignalP(1-21); go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0004571 - mannosyl-oligosaccharide 1,2-alpha-mannosidase activity [Evidence IEA]; go_function: GO:0005509 - calcium ion binding [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_10360A COG:P; EggNog:ENOG410PJ1N; InterPro:IPR036314,IPR019833,IPR019832,IPR019831, IPR036324,IPR001189; PFAM:PF02777,PF00081; go_function: GO:0004784 - superoxide dismutase activity [Evidence IEA]; go_function: GO:0046872 - metal ion binding [Evidence IEA]; go_process: GO:0006801 - superoxide metabolic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_10361S COG:Q; EggNog:ENOG410PHGE; InterPro:IPR002347,IPR036291,IPR020904; PFAM:PF00106,PF13561,PF08659; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_10363S TransMembrane:1 (o12-29i) AKAW2_10364S COG:I,J,T; EggNog:ENOG410PKDU; InterPro:IPR023631,IPR036928; PFAM:PF01425 AKAW2_10365A COG:C; EggNog:ENOG410PKX2; InterPro:IPR036188,IPR023753; PFAM:PF07992,PF00070; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_10366A COG:M; EggNog:ENOG410PI1N; InterPro:IPR002523,IPR002110,IPR036770,IPR020683; PFAM:PF13857,PF12796,PF00023,PF01544,PF13637, PF13606; TransMembrane:2 (o957-983i995-1016o); go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_function: GO:0046873 - metal ion transmembrane transporter activity [Evidence IEA]; go_process: GO:0030001 - metal ion transport [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_10367A COG:S; EggNog:ENOG410PK0F AKAW2_10368S COG:E; EggNog:ENOG410PHRT; InterPro:IPR004839,IPR015424,IPR015421,IPR015422; PFAM:PF00155; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0030170 - pyridoxal phosphate binding [Evidence IEA]; go_process: GO:0009058 - biosynthetic process [Evidence IEA] AKAW2_10369S CAZy:GH55; COG:G; EggNog:ENOG410PK13; InterPro:IPR012334,IPR011050,IPR024535; PFAM:PF12708; SECRETED:SignalP(1-20) AKAW2_10370S CAZy:AA16; COG:S; EggNog:ENOG410PP2H; InterPro:IPR004302; PFAM:PF03067; SECRETED:SignalP(1-19) AKAW2_10371A COG:S; EggNog:ENOG410PMM1; InterPro:IPR004152,IPR008942; PFAM:PF03127; go_process: GO:0006886 - intracellular protein transport [Evidence IEA] AKAW2_10372A COG:J; EggNog:ENOG410PKT5; InterPro:IPR036394,IPR001063,IPR005721,IPR018260; PFAM:PF00237; go_component: GO:0005840 - ribosome [Evidence IEA]; go_component: GO:0015934 - large ribosomal subunit [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_process: GO:0006412 - translation [Evidence IEA] AKAW2_10373A COG:K; EggNog:ENOG410PHDW; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_10374S COG:Q; EggNog:ENOG410PHW8; InterPro:IPR002347,IPR036291,IPR020904; PFAM:PF00106,PF13561,PF08659,PF01370; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_10375S COG:P,Q; EggNog:ENOG410PJV5; InterPro:IPR013112,IPR017927,IPR013130,IPR013121, IPR039261; PFAM:PF08022,PF01794,PF08030; TransMembrane:5 (o37-59i201-219o239-256i268-286o298-320i); go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_10376A COG:Q; EggNog:ENOG410PG6M; InterPro:IPR034001,IPR043926,IPR027417,IPR003593, IPR010929,IPR017871,IPR029481,IPR003439,IPR013525, IPR034003; PFAM:PF01061,PF00005,PF06422,PF14510; TransMembrane:11 (o574-594i606-628o681-702i714-733o819-839i1235-1256o1268- 1290i1311-1338o1358-1380i1392-1416o1509-1529i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA]; go_function: GO:0042626 - ATPase-coupled transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_10377A BUSCO:EOG09262E4T; COG:O; EggNog:ENOG410PH0W; InterPro:IPR009060,IPR036249,IPR001012,IPR006577, IPR029071; PFAM:PF00789,PF14555; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_10378S BUSCO:EOG09261Q5L; COG:A; EggNog:ENOG410PHHT; InterPro:IPR030844,IPR000719,IPR011009,IPR000571, IPR041332; PFAM:PF18101; go_component: GO:0031251 - PAN complex [Evidence IEA]; go_function: GO:0003723 - RNA binding [Evidence IEA]; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0046872 - metal ion binding [Evidence IEA]; go_process: GO:0000289 - nuclear-transcribed mRNA poly(A) tail shortening [Evidence IEA]; go_process: GO:0006397 - mRNA processing [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_10379A COG:S; EggNog:ENOG410PH5P; InterPro:IPR036378,IPR000782; PFAM:PF02469; SECRETED:SignalP(1-16) AKAW2_10380A COG:A; EggNog:ENOG410PRCE; InterPro:IPR010920,IPR017132,IPR001163; PFAM:PF01423; go_process: GO:0000398 - mRNA splicing, via spliceosome [Evidence IEA]; go_process: GO:0000956 - nuclear-transcribed mRNA catabolic process [Evidence IEA] AKAW2_10381S TransMembrane:1 (i103-127o) AKAW2_10382S COG:S; EggNog:ENOG410PMUE; InterPro:IPR001138; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_10383S COG:Q; EggNog:ENOG410PFEK; InterPro:IPR000627,IPR007535,IPR039390,IPR015889; PFAM:PF04444,PF00775; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0008199 - ferric iron binding [Evidence IEA]; go_function: GO:0016702 - oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [Evidence IEA]; go_function: GO:0018576 - catechol 1,2-dioxygenase activity [Evidence IEA]; go_process: GO:0006725 - cellular aromatic compound metabolic process [Evidence IEA]; go_process: GO:0009712 - catechol-containing compound metabolic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_10384A BUSCO:EOG09263OZR; COG:U; EggNog:ENOG410PIKE; InterPro:IPR032914,IPR001180; go_process: GO:0016192 - vesicle-mediated transport [Evidence IEA] AKAW2_10385S BUSCO:EOG09261OXD; COG:U; EggNog:ENOG410PFYG; InterPro:IPR012955; PFAM:PF08172; TransMembrane:1 (o690-708i); go_component: GO:0030173 - integral component of Golgi membrane [Evidence IEA]; go_process: GO:0006891 - intra-Golgi vesicle-mediated transport [Evidence IEA] AKAW2_10386A COG:S; EggNog:ENOG410PMZJ; InterPro:IPR038921; SECRETED:SignalP(1-19) AKAW2_10387S InterPro:IPR008427; PFAM:PF05730; SECRETED:SignalP(1-18); TransMembrane:1 (n3-13c18/19o191-215i) AKAW2_10389S COG:S; EggNog:ENOG410PN9Z; InterPro:IPR021706,IPR021851; PFAM:PF11937,PF11693; SECRETED:SignalP(1-17) AKAW2_10390S BUSCO:EOG092648VW; COG:A; EggNog:ENOG410PIJ4; InterPro:IPR029063,IPR000692; PFAM:PF01269; go_function: GO:0003723 - RNA binding [Evidence IEA]; go_function: GO:0008168 - methyltransferase activity [Evidence IEA]; go_process: GO:0006364 - rRNA processing [Evidence IEA] AKAW2_10391S COG:M; EggNog:ENOG410PJWK; InterPro:IPR036291,IPR001509; PFAM:PF04321,PF01073,PF01370; go_function: GO:0003824 - catalytic activity [Evidence IEA] AKAW2_10392S COG:O; EggNog:ENOG410PGP4; InterPro:IPR001431,IPR011765,IPR007863,IPR011249; MEROPS:MER0043985; PFAM:PF05193,PF00675; go_function: GO:0046872 - metal ion binding [Evidence IEA]; go_process: GO:0006508 - proteolysis [Evidence IEA] AKAW2_10393A COG:S; EggNog:ENOG410PQR3; InterPro:IPR006461; PFAM:PF04749; TransMembrane:1 (o49-70i) AKAW2_10394A COG:G; EggNog:ENOG410QDAM; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i32-52o72-89i101-121o127-148i160-182o188-211i237-258o270- 288i300-319o325-345i366-386o392-417i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_10395S BUSCO:EOG09264FXB; COG:J; EggNog:ENOG410PFYD; InterPro:IPR023270,IPR029063,IPR018314,IPR023267, IPR001678; PFAM:PF01189; go_function: GO:0003723 - RNA binding [Evidence IEA]; go_function: GO:0008168 - methyltransferase activity [Evidence IEA]; go_function: GO:0016428 - tRNA (cytosine-5-)-methyltransferase activity [Evidence IEA]; go_process: GO:0001510 - RNA methylation [Evidence IEA] AKAW2_10396A COG:Q; EggNog:ENOG410PUA3; InterPro:IPR013154,IPR013149,IPR036291,IPR011032, IPR020843; PFAM:PF00107,PF08240; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_10397S CAZy:GH35; COG:G; EggNog:ENOG410PGTY; InterPro:IPR019801,IPR025300,IPR025972,IPR037110, IPR008979,IPR036833,IPR018954,IPR017853,IPR001944, IPR031330; PFAM:PF13363,PF10435,PF01301,PF13364; go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_10398A COG:S; EggNog:ENOG410PJS5; InterPro:IPR023213,IPR003480; PFAM:PF02458; go_function: GO:0016747 - transferase activity, transferring acyl groups other than amino-acyl groups [Evidence IEA] AKAW2_10399S COG:S; EggNog:ENOG410PN7N; InterPro:IPR007219; TransMembrane:2 (i103-124o136-157i); go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA] AKAW2_10400S COG:S; EggNog:ENOG410PHFD; InterPro:IPR036291,IPR000534; PFAM:PF01118; go_function: GO:0016620 - oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Evidence IEA]; go_function: GO:0051287 - NAD binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_10401S COG:M; EggNog:ENOG410PXPX; InterPro:IPR002110,IPR020683,IPR025676,IPR036770; PFAM:PF12796,PF00023,PF13637,PF14420; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_10402S COG:C; EggNog:ENOG410PM8Z; InterPro:IPR017938,IPR000951,IPR012675,IPR001041, IPR017927,IPR006058,IPR005302,IPR001433,IPR011037, IPR039261,IPR036010; PFAM:PF00175,PF00111,PF03473; TransMembrane:1 (o357-376i); go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0009055 - electron transfer activity [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0030151 - molybdenum ion binding [Evidence IEA]; go_function: GO:0030170 - pyridoxal phosphate binding [Evidence IEA]; go_function: GO:0051536 - iron-sulfur cluster binding [Evidence IEA]; go_function: GO:0051537 - 2 iron, 2 sulfur cluster binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_10403A COG:Q; EggNog:ENOG410PKHI; InterPro:IPR001447,IPR038765; PFAM:PF00797; go_function: GO:0016407 - acetyltransferase activity [Evidence IEA] AKAW2_10405S COG:M; EggNog:ENOG410PWIQ AKAW2_10406S COG:S; EggNog:ENOG410PSN3; InterPro:IPR023213 AKAW2_10407S COG:I; EggNog:ENOG410PJ2Y; InterPro:IPR014030,IPR018201,IPR016039,IPR020841; PFAM:PF00109; go_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein] synthase activity [Evidence IEA]; go_function: GO:0016746 - transferase activity, transferring acyl groups [Evidence IEA]; go_process: GO:0006633 - fatty acid biosynthetic process [Evidence IEA] AKAW2_10408S COG:I; EggNog:ENOG410PJ2Y; InterPro:IPR016036,IPR016035,IPR001227,IPR014043, IPR020807,IPR042104; PFAM:PF14765,PF00698; go_function: GO:0016740 - transferase activity [Evidence IEA] AKAW2_10409S COG:I; EggNog:ENOG410PJ2Y; InterPro:IPR009081,IPR013154,IPR013149,IPR036736, IPR036291,IPR011032,IPR013968,IPR020843,IPR002364; PFAM:PF00107,PF00106,PF08240,PF08659,PF00550, PF13602; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_10410S InterPro:IPR036736,IPR009081; PFAM:PF00550 AKAW2_10411S CAZy:GT2_Glyco_tranf_2; COG:U; EggNog:ENOG410PGTI; InterPro:IPR029044; PFAM:PF13632,PF13641; TransMembrane:6 (i187-210o230-255i513-534o554-575i582-598o610-631i) AKAW2_10412A COG:T; EggNog:ENOG410PW4Q; InterPro:IPR000719,IPR011009; PFAM:PF00069; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_10413S COG:S; EggNog:ENOG410PZGQ; TransMembrane:1 (o65-88i) AKAW2_10414A COG:S; EggNog:ENOG410Q2NZ AKAW2_10415S COG:A; EggNog:ENOG410PKD8; InterPro:IPR027417,IPR007111,IPR015943,IPR011047, IPR001680,IPR031359,IPR017986; PFAM:PF05729,PF00400,PF17100; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_10416S COG:U; EggNog:ENOG410PJJN; InterPro:IPR000757,IPR013320; TransMembrane:1 (i79-96o); go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_10417A BUSCO:EOG09264HOY; COG:S; EggNog:ENOG410PGA2; InterPro:IPR039604 AKAW2_10418S BUSCO:EOG09264904; COG:K; EggNog:ENOG410PN0D; InterPro:IPR036710,IPR005571,IPR020608,IPR020609, IPR000783,IPR014381,IPR035913,IPR039531; PFAM:PF01191,PF03871; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0003899 - DNA-directed 5'-3' RNA polymerase activity [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA] AKAW2_10419A COG:I; EggNog:ENOG410PWJI; InterPro:IPR036291,IPR026055,IPR013120; PFAM:PF07993; go_function: GO:0080019 - fatty-acyl-CoA reductase (alcohol-forming) activity [Evidence IEA] AKAW2_10420A COG:S; EggNog:ENOG410PFIG; TransMembrane:7 (o32-53i65-85o105-129i150-168o188-217i229-248o268-285i) AKAW2_10421A BUSCO:EOG09262K9A; COG:E; EggNog:ENOG410PGU7; InterPro:IPR001917,IPR004839,IPR005861,IPR015424, IPR015421,IPR015422; PFAM:PF00155; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0004400 - histidinol-phosphate transaminase activity [Evidence IEA]; go_function: GO:0016740 - transferase activity [Evidence IEA]; go_function: GO:0030170 - pyridoxal phosphate binding [Evidence IEA]; go_process: GO:0000105 - histidine biosynthetic process [Evidence IEA]; go_process: GO:0009058 - biosynthetic process [Evidence IEA] AKAW2_10422A BUSCO:EOG09263B7X; COG:U; EggNog:ENOG410PGPT; InterPro:IPR015222; PFAM:PF09139; go_function: GO:0004605 - phosphatidate cytidylyltransferase activity [Evidence IEA]; go_process: GO:0032049 - cardiolipin biosynthetic process [Evidence IEA] AKAW2_10423S COG:D; EggNog:ENOG410PPAQ; InterPro:IPR001370; MEROPS:MER0018608; PFAM:PF00653 AKAW2_10424A COG:S; EggNog:ENOG410PPJX; InterPro:IPR036236,IPR040107,IPR022755,IPR003604, IPR013087; PFAM:PF12171,PF12874; go_component: GO:0005681 - spliceosomal complex [Evidence IEA]; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0000398 - mRNA splicing, via spliceosome [Evidence IEA] AKAW2_10425S COG:S; EggNog:ENOG410PS1D; InterPro:IPR001810,IPR036047; PFAM:PF00646; TransMembrane:1 (i139-159o); go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_10426A COG:Q; EggNog:ENOG410PG34; InterPro:IPR001128,IPR017972,IPR002401,IPR036396; PFAM:PF00067; SMCOG1034:cytochrome P450; antiSMASH:Cluster_1.7; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_10427A COG:Q; EggNog:ENOG410Q24T; InterPro:IPR001128,IPR036396; antiSMASH:Cluster_1.7; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_10428A COG:K; EggNog:ENOG410PJIV; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172; TransMembrane:3 (o274-291i298-316o521-545i); antiSMASH:Cluster_1.7; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_10429A COG:S; EggNog:ENOG410Q1V1; SECRETED:SignalP(1-20); antiSMASH:Cluster_1.7 AKAW2_10430A antiSMASH:Cluster_1.7 AKAW2_10431S COG:S; EggNog:ENOG410Q00G; InterPro:IPR038883; antiSMASH:Cluster_1.7 AKAW2_10432A COG:A; EggNog:ENOG410PHJT; InterPro:IPR000504,IPR039722,IPR005120,IPR035979, IPR012677; PFAM:PF03467,PF00076; antiSMASH:Cluster_1.7; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_process: GO:0000184 - nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [Evidence IEA] AKAW2_10433S COG:D,T; EggNog:ENOG410PGS9; InterPro:IPR004843,IPR006186; PFAM:PF00149; antiSMASH:Cluster_1.7; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_10434S COG:C,H; EggNog:ENOG410PIRA; InterPro:IPR036188,IPR002938,IPR036249,IPR038220, IPR012941; PFAM:PF07976,PF01494; SMCOG1050:monooxygenase FAD-binding; antiSMASH:Cluster_1.7; go_function: GO:0071949 - FAD binding [Evidence IEA] AKAW2_10435S COG:I; EggNog:ENOG410Q286; InterPro:IPR000873,IPR009081,IPR036736,IPR029058, IPR001031,IPR020802,IPR042099,IPR020845; PFAM:PF00501,PF00550,PF00975; SMCOG1002:AMP-dependent synthetase and ligase; antiSMASH:Cluster_1.7; go_function: GO:0016788 - hydrolase activity, acting on ester bonds [Evidence IEA]; go_process: GO:0009058 - biosynthetic process [Evidence IEA] AKAW2_10436A COG:L; EggNog:ENOG410PS5H; InterPro:IPR015797,IPR000086; PFAM:PF00293; antiSMASH:Cluster_1.7; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_10437S COG:I; EggNog:ENOG410PMS5; InterPro:IPR000873,IPR009081,IPR006162,IPR036736, IPR042099,IPR010071,IPR020845; PFAM:PF00501,PF00550; SMCOG1002:AMP-dependent synthetase and ligase; TransMembrane:1 (o718-734i); antiSMASH:Cluster_1.7 AKAW2_10438A COG:G; EggNog:ENOG410PJKR; InterPro:IPR011701,IPR036259; PFAM:PF07690; SMCOG1137:Major facilitator superfamily MFS 1; TransMembrane:11 (i50-72o92-115i122-141o147-168i180-199o211-231i255- 276o318-337i344-367o379-398i410-432o); antiSMASH:Cluster_1.7; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_10439S COG:T; EggNog:ENOG410PNTH; InterPro:IPR000719,IPR011009; PFAM:PF07714,PF00069; SMCOG1030:serine/threonine protein kinase; antiSMASH:Cluster_1.7; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_10440S COG:O; EggNog:ENOG410PG7J; InterPro:IPR008257,IPR032466; MEROPS:MER0001260; PFAM:PF01244; antiSMASH:Cluster_1.7; go_function: GO:0070573 - metallodipeptidase activity [Evidence IEA]; go_process: GO:0006508 - proteolysis [Evidence IEA] AKAW2_10441A antiSMASH:Cluster_1.7 AKAW2_10442S COG:S; EggNog:ENOG410PXKU; InterPro:IPR011990,IPR010730; PFAM:PF06985,PF13374; antiSMASH:Cluster_1.7; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_10443S COG:C; EggNog:ENOG410PGWZ; InterPro:IPR007197,IPR013917,IPR034556,IPR029039, IPR013785,IPR008254; PFAM:PF04055,PF08608; antiSMASH:Cluster_1.7; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0010181 - FMN binding [Evidence IEA]; go_function: GO:0051536 - iron-sulfur cluster binding [Evidence IEA]; go_function: GO:0051539 - 4 iron, 4 sulfur cluster binding [Evidence IEA]; go_process: GO:0008033 - tRNA processing [Evidence IEA] AKAW2_10444A COG:G; EggNog:ENOG410PIK6; InterPro:IPR005828,IPR036259; TransMembrane:3 (i12-32o52-72i84-102o); antiSMASH:Cluster_1.8; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_10445S COG:S; EggNog:ENOG410PNYD; TransMembrane:7 (o12-31i43-66o86-110i117-137o170-190i202-220o240-260i) AKAW2_10446A COG:S; EggNog:ENOG410PJFE; InterPro:IPR015943,IPR019405; PFAM:PF10282; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_10447A CAZy:GH5; COG:G; EggNog:ENOG410PGYW; InterPro:IPR001547,IPR035971,IPR017853,IPR000254; PFAM:PF00734,PF00150; SECRETED:SignalP(1-19); go_component: GO:0005576 - extracellular region [Evidence IEA]; go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_function: GO:0030248 - cellulose binding [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA]; go_process: GO:0071704 - organic substance metabolic process [Evidence IEA] AKAW2_10448A CAZy:GH7; COG:G; EggNog:ENOG410PHJ4; InterPro:IPR035971,IPR037019,IPR000254,IPR001722, IPR013320; PFAM:PF00734,PF00840; SECRETED:SignalP(1-21); go_component: GO:0005576 - extracellular region [Evidence IEA]; go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_function: GO:0030248 - cellulose binding [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_10449S COG:G; EggNog:ENOG410QDS0; InterPro:IPR041729,IPR004810,IPR002376,IPR036477, IPR002912,IPR044074; PFAM:PF01842,PF00551; go_function: GO:0008864 - formyltetrahydrofolate deformylase activity [Evidence IEA]; go_function: GO:0016742 - hydroxymethyl-, formyl-and related transferase activity [Evidence IEA]; go_process: GO:0006189 - 'de novo' IMP biosynthetic process [Evidence IEA]; go_process: GO:0009058 - biosynthetic process [Evidence IEA] AKAW2_10450A COG:P; EggNog:ENOG410PMJH; InterPro:IPR024041,IPR029020; PFAM:PF00909; TransMembrane:9 (o16-36i48-66o101-121i128-150o170-191i212-229o241-262i274- 293o299-317i); go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0008519 - ammonium transmembrane transporter activity [Evidence IEA]; go_process: GO:0015696 - ammonium transport [Evidence IEA] AKAW2_10451S BUSCO:EOG09265PUI; COG:U; EggNog:ENOG410PRYA; InterPro:IPR023391,IPR008158,IPR001901; PFAM:PF00584; TransMembrane:1 (i34-55o); antiSMASH:Cluster_1.9; go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0015450 - P-P-bond-hydrolysis-driven protein transmembrane transporter activity [Evidence IEA]; go_process: GO:0006605 - protein targeting [Evidence IEA]; go_process: GO:0006886 - intracellular protein transport [Evidence IEA]; go_process: GO:0015031 - protein transport [Evidence IEA] AKAW2_10452S COG:S; EggNog:ENOG410PX9A; InterPro:IPR020915; PFAM:PF11578; antiSMASH:Cluster_1.9 AKAW2_10453A COG:S; EggNog:ENOG410PSTT; InterPro:IPR036864,IPR021858,IPR001138; PFAM:PF00172; antiSMASH:Cluster_1.9; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_10454A COG:E; EggNog:ENOG410PJ40; InterPro:IPR017144,IPR002933,IPR011650,IPR017439, IPR036264; MEROPS:MER0014418; PFAM:PF01546,PF07687; SMCOG1244:amidohydrolase; antiSMASH:Cluster_1.9; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_10455S COG:G; EggNog:ENOG410QDJA; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; SMCOG1106:major facilitator transporter; TransMembrane:12 (i64-81o110-128i135-153o165-185i197-216o228-248i298- 322o334-357i362-382o394-415i427-445o457-478i); antiSMASH:Cluster_1.9; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_10456A COG:S; EggNog:ENOG410PXAA; antiSMASH:Cluster_1.9 AKAW2_10457S COG:S; EggNog:ENOG410PFGS; InterPro:IPR011118,IPR029058; PFAM:PF07519; SECRETED:SignalP(1-26); antiSMASH:Cluster_1.9 AKAW2_10458S COG:S; EggNog:ENOG410PFK2; InterPro:IPR036188; PFAM:PF13450; antiSMASH:Cluster_1.9 AKAW2_10459A COG:Q; EggNog:ENOG410PJA1; InterPro:IPR016036,IPR016035,IPR016039,IPR018201, IPR042104,IPR014030,IPR011032,IPR013968,IPR013154, IPR001227,IPR032821,IPR014031,IPR014043,IPR002328, IPR020807,IPR020843,IPR020841,IPR013149,IPR029063, IPR036291,IPR013217; PFAM:PF16197,PF00109,PF08659,PF13489,PF02801, PF00698,PF13847,PF13649,PF13602,PF14765,PF00107,PF00106, PF08242,PF08241; SMCOG1022:Beta-ketoacyl synthase; antiSMASH:Cluster_1.9; go_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein] synthase activity [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0016740 - transferase activity [Evidence IEA]; go_function: GO:0016746 - transferase activity, transferring acyl groups [Evidence IEA]; go_process: GO:0006633 - fatty acid biosynthetic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_10460A COG:E; EggNog:ENOG410Q0GJ; InterPro:IPR005645,IPR029058; PFAM:PF03959; TransMembrane:1 (o87-105i); antiSMASH:Cluster_1.9 AKAW2_10461S COG:S; EggNog:ENOG410PQ74; TransMembrane:7 (o20-41i53-74o100-123i135-157o177-199i211-232o244-270i); antiSMASH:Cluster_1.9 AKAW2_10462S COG:I; EggNog:ENOG410PJ8T; InterPro:IPR000873,IPR009081,IPR036736,IPR036291, IPR013120,IPR042099,IPR020845; PFAM:PF00501,PF00550,PF01370,PF07993; SMCOG1002:AMP-dependent synthetase and ligase; antiSMASH:Cluster_1.9 AKAW2_10463A antiSMASH:Cluster_1.9 AKAW2_10464A CAZy:GH28; COG:G; EggNog:ENOG410PFRD; InterPro:IPR000743,IPR012334,IPR006626,IPR011050; PFAM:PF00295; SECRETED:SignalP(1-18); antiSMASH:Cluster_1.9; go_function: GO:0004650 - polygalacturonase activity [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_10465S antiSMASH:Cluster_1.9 AKAW2_10466A COG:P; EggNog:ENOG410Q2RJ; InterPro:IPR032506,IPR017850,IPR024607,IPR000917; PFAM:PF16347,PF01663,PF00884; antiSMASH:Cluster_1.9; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0008484 - sulfuric ester hydrolase activity [Evidence IEA] AKAW2_10467A CAZy:AA7; COG:C; EggNog:ENOG410PM34; InterPro:IPR006094,IPR036318,IPR016166,IPR012951; PFAM:PF08031,PF01565; SECRETED:SignalP(1-21); SMCOG1138:FAD linked oxidase domain protein; antiSMASH:Cluster_1.10; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_function: GO:0071949 - FAD binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_10468A COG:G; EggNog:ENOG410PGSS; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; SMCOG1106:major facilitator transporter; TransMembrane:12 (i100-118o138-155i167-185o197-216i228-249o261-279i340- 361o373-393i405-425o431-455i467-487o502-522i); antiSMASH:Cluster_1.10; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_10469A COG:M; EggNog:ENOG410PPZS; InterPro:IPR001509,IPR036291; PFAM:PF04321,PF01073,PF13460,PF01370; SMCOG1010:NAD-dependent epimerase/dehydratase; antiSMASH:Cluster_1.10; go_function: GO:0003824 - catalytic activity [Evidence IEA] AKAW2_10470A COG:S; EggNog:ENOG410PXZA AKAW2_10471A COG:S; EggNog:ENOG410PVGK; InterPro:IPR039020; TransMembrane:7 (o35-55i67-84o90-110i122-141o153-173i209-227o239-262i) AKAW2_10472A COG:Z; EggNog:ENOG410PPAP; InterPro:IPR040632,IPR027417; PFAM:PF17784; TransMembrane:1 (o240-260i) AKAW2_10473A COG:S; EggNog:ENOG410PZ7E AKAW2_10474A COG:S; EggNog:ENOG410PX97 AKAW2_10475A COG:O; EggNog:ENOG410PH0R; InterPro:IPR036388,IPR000994,IPR036390,IPR002468, IPR036005,IPR001714,IPR018349; MEROPS:MER0001728; PFAM:PF00557; go_function: GO:0070006 - metalloaminopeptidase activity [Evidence IEA]; go_process: GO:0006508 - proteolysis [Evidence IEA] AKAW2_10476S COG:O; EggNog:ENOG410PI0E; InterPro:IPR000994,IPR002467,IPR036005,IPR001714, IPR031615; MEROPS:MER0001342; PFAM:PF15801,PF00557; go_function: GO:0070006 - metalloaminopeptidase activity [Evidence IEA]; go_process: GO:0006508 - proteolysis [Evidence IEA] AKAW2_10477A COG:S; EggNog:ENOG410PT1S AKAW2_10478S SECRETED:SignalP(1-20) AKAW2_10479A COG:S; EggNog:ENOG410PWFD; InterPro:IPR036864,IPR001138; PFAM:PF00172; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_10480A COG:G; EggNog:ENOG410PFZ6; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690,PF06609; TransMembrane:11 (o55-75i121-145o151-172i179-198o210-230i251-270o282- 299i319-340o360-379i386-404o516-538i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_10481A COG:S; EggNog:ENOG410PP0G; InterPro:IPR006680,IPR032466,IPR032465; PFAM:PF04909; go_function: GO:0016787 - hydrolase activity [Evidence IEA]; go_function: GO:0016831 - carboxy-lyase activity [Evidence IEA] AKAW2_10482S COG:S; EggNog:ENOG410PNBP; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_10483A COG:S; EggNog:ENOG410PQB5; TransMembrane:2 (i121-140o160-177i) AKAW2_10484A COG:S; EggNog:ENOG410PRQZ; SECRETED:SignalP(1-17) AKAW2_10485S COG:S; EggNog:ENOG410PSS4; SECRETED:SignalP(1-18); antiSMASH:Cluster_1.11 AKAW2_10486S COG:S; EggNog:ENOG410PNPP; SECRETED:SignalP(1-22); TransMembrane:7 (o34-55i67-92o112-138i150-173o193-219i231-251o263-285i); antiSMASH:Cluster_1.11 AKAW2_10487S COG:Q; EggNog:ENOG410PN1F; InterPro:IPR036291,IPR002347; PFAM:PF08659,PF00106,PF13561; SMCOG1001:short-chain dehydrogenase/reductase SDR; antiSMASH:Cluster_1.11; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_10488S COG:H; EggNog:ENOG410PG02; InterPro:IPR002937,IPR036188,IPR008150; PFAM:PF01593; SMCOG1222:dehydrogenase; antiSMASH:Cluster_1.11; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_10489A COG:I; EggNog:ENOG410PM2C; InterPro:IPR019845,IPR008949; PFAM:PF00494; antiSMASH:Cluster_1.11; go_function: GO:0016765 - transferase activity, transferring alkyl or aryl (other than methyl) groups [Evidence IEA] AKAW2_10490A COG:T; EggNog:ENOG410PMT2; InterPro:IPR000719,IPR011009,IPR017441; PFAM:PF07714,PF00069; SMCOG1030:serine/threonine protein kinase; antiSMASH:Cluster_1.11; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_10491A COG:S; EggNog:ENOG410PX69; TransMembrane:5 (o35-57i69-91o116-136i148-172o192-211i); antiSMASH:Cluster_1.11 AKAW2_10492S CAZy:AA7; COG:C; EggNog:ENOG410PGWT; InterPro:IPR016166,IPR006094,IPR036318; PFAM:PF01565; SMCOG1138:FAD linked oxidase domain protein; antiSMASH:Cluster_1.11; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_function: GO:0071949 - FAD binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_10493A COG:O; EggNog:ENOG410Q20Q; SECRETED:SignalP(1-18) AKAW2_10494S COG:O; EggNog:ENOG410PIV9; InterPro:IPR038765,IPR036959,IPR041507,IPR001578, IPR017390; MEROPS:MER0013494; PFAM:PF01088,PF18031; go_function: GO:0004843 - thiol-dependent ubiquitin-specific protease activity [Evidence IEA]; go_process: GO:0006511 - ubiquitin-dependent protein catabolic process [Evidence IEA]; go_process: GO:0016579 - protein deubiquitination [Evidence IEA] AKAW2_10495A COG:I; EggNog:ENOG410PJ5D; InterPro:IPR011009,IPR007521; PFAM:PF01633,PF04428,PF01636; go_function: GO:0016773 - phosphotransferase activity, alcohol group as acceptor [Evidence IEA] AKAW2_10496A COG:S; EggNog:ENOG410PS8S; InterPro:IPR016181,IPR000182; PFAM:PF13508,PF13527,PF13673,PF00583; go_function: GO:0008080 - N-acetyltransferase activity [Evidence IEA] AKAW2_10497A COG:I; EggNog:ENOG410PK2J; InterPro:IPR007312,IPR017850; PFAM:PF04185; SECRETED:SignalP(1-20); go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0016788 - hydrolase activity, acting on ester bonds [Evidence IEA] AKAW2_10498S CAZy:AA1; COG:Q; EggNog:ENOG410PHK0; InterPro:IPR008972,IPR011707,IPR011706,IPR033138, IPR002355,IPR001117; PFAM:PF00394,PF07731; go_function: GO:0005507 - copper ion binding [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_10499A BUSCO:EOG092624SJ; COG:I; EggNog:ENOG410PGAF; InterPro:IPR004776; PFAM:PF03547; TransMembrane:10 (o44-69i81-100o112-133i145-166o186-204i379-395o401- 422i482-501o513-531i552-571o); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_10500S COG:T; EggNog:ENOG410PHWT; InterPro:IPR000719,IPR011009,IPR008271; PFAM:PF07714,PF00069; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_10501S COG:S; EggNog:ENOG410PNKJ; InterPro:IPR036291,IPR008030; PFAM:PF13460,PF05368 AKAW2_10503S CAZy:GH16; COG:G; EggNog:ENOG410PJB2; InterPro:IPR000757,IPR013320,IPR017168; PFAM:PF00722; SECRETED:SignalP(1-19); go_component: GO:0005618 - cell wall [Evidence IEA]; go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_function: GO:0016798 - hydrolase activity, acting on glycosyl bonds [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA]; go_process: GO:0071555 - cell wall organization [Evidence IEA] AKAW2_10504A COG:S; EggNog:ENOG410QEAG; TransMembrane:1 (i147-166o) AKAW2_10505S COG:J; EggNog:ENOG410PG6E; InterPro:IPR036621,IPR006195,IPR002320,IPR004154, IPR033728,IPR002314; PFAM:PF03129,PF00587; go_component: GO:0005737 - cytoplasm [Evidence IEA]; go_function: GO:0000166 - nucleotide binding [Evidence IEA]; go_function: GO:0004812 - aminoacyl-tRNA ligase activity [Evidence IEA]; go_function: GO:0004829 - threonine-tRNA ligase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006418 - tRNA aminoacylation for protein translation [Evidence IEA]; go_process: GO:0006435 - threonyl-tRNA aminoacylation [Evidence IEA] AKAW2_10506S COG:S; EggNog:ENOG410PMPE; InterPro:IPR007219; PFAM:PF04082; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA] AKAW2_10507A COG:G; EggNog:ENOG410PMTW; InterPro:IPR005828,IPR003663,IPR036259,IPR020846; PFAM:PF00083,PF07690; TransMembrane:12 (i16-33o72-90i102-123o129-146i158-180o192-212i285-307o327- 348i355-374o386-410i422-443o455-474i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_10508S COG:S; EggNog:ENOG410PMQ4; InterPro:IPR006680,IPR032466; PFAM:PF04909; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_10509S COG:S; EggNog:ENOG410PM77; InterPro:IPR029062,IPR032633; MEROPS:MER0038141; PFAM:PF01965,PF17124 AKAW2_10510A SECRETED:SignalP(1-19) AKAW2_10511A CAZy:GH31; COG:G; EggNog:ENOG410PHCX; InterPro:IPR025887,IPR000322,IPR017853,IPR011013, IPR013780,IPR031727; PFAM:PF13802,PF01055,PF16863; SECRETED:SignalP(1-14); go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_function: GO:0030246 - carbohydrate binding [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_10513A COG:Q; EggNog:ENOG410PJR0; InterPro:IPR013154,IPR013149,IPR002328,IPR036291, IPR011032; PFAM:PF00107,PF08240; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_10514A COG:Q; EggNog:ENOG410PWWV; InterPro:IPR015889; SECRETED:SignalP(1-18); go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016702 - oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_10516S COG:C; EggNog:ENOG410PPI0; InterPro:IPR006808; PFAM:PF04718; go_component: GO:0000276 - mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) [Evidence IEA]; go_function: GO:0015078 - proton transmembrane transporter activity [Evidence IEA]; go_process: GO:0015986 - ATP synthesis coupled proton transport [Evidence IEA] AKAW2_10517A COG:S; EggNog:ENOG410PQ91; SECRETED:SignalP(1-16) AKAW2_10518S COG:O; EggNog:ENOG410PX2Z; InterPro:IPR027417,IPR003593,IPR003959; PFAM:PF00004; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA] AKAW2_10519A COG:S; EggNog:ENOG410QE63; InterPro:IPR029063,IPR019410; PFAM:PF10294 AKAW2_10520A COG:U; EggNog:ENOG410PJD3; InterPro:IPR017899,IPR017898,IPR037206,IPR037202, IPR038358,IPR007143; PFAM:PF03997; go_component: GO:0000813 - ESCRT I complex [Evidence IEA]; go_process: GO:0032509 - endosome transport via multivesicular body sorting pathway [Evidence IEA] AKAW2_10521S BUSCO:EOG09262N5O; COG:J; EggNog:ENOG410PH1G; InterPro:IPR005343; PFAM:PF03715 AKAW2_10522A COG:P; EggNog:ENOG410PHY9; InterPro:IPR003445; TransMembrane:2 (o70-88i100-117o); go_function: GO:0008324 - cation transmembrane transporter activity [Evidence IEA]; go_process: GO:0006812 - cation transport [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_10523A COG:P; EggNog:ENOG410PHY9; InterPro:IPR003445; TransMembrane:8 (o20-42i54-73o85-105i317-346o358-379i391-418o456-479i500- 526o); go_function: GO:0008324 - cation transmembrane transporter activity [Evidence IEA]; go_process: GO:0006812 - cation transport [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_10524S COG:S; EggNog:ENOG410Q28V; InterPro:IPR006694; PFAM:PF04116; TransMembrane:3 (i59-80o86-105i169-189o); go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0008610 - lipid biosynthetic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_10525S COG:S; EggNog:ENOG410PSQJ; InterPro:IPR019626; PFAM:PF10685 AKAW2_10527S COG:S; EggNog:ENOG410PHVW; InterPro:IPR004827; PFAM:PF00170; go_function: GO:0003700 - DNA-binding transcription factor activity [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_10528S COG:Q; EggNog:ENOG410PGTV; InterPro:IPR027794,IPR036866; PFAM:PF13691; go_process: GO:0008033 - tRNA processing [Evidence IEA] AKAW2_10529A COG:I; EggNog:ENOG410PKVZ; InterPro:IPR000560,IPR029033; PFAM:PF00328 AKAW2_10531S BUSCO:EOG09263274; COG:U; EggNog:ENOG410PH4C; InterPro:IPR039400,IPR006762,IPR027417; PFAM:PF04670; go_function: GO:0005525 - GTP binding [Evidence IEA] AKAW2_10532S COG:E; EggNog:ENOG410PJXB; InterPro:IPR036400,IPR001199; PFAM:PF00173; TransMembrane:1 (i41-59o) AKAW2_10533A BUSCO:EOG09265SHL; COG:J; EggNog:ENOG410PQUS; InterPro:IPR004977; PFAM:PF03297 AKAW2_10534A COG:S; EggNog:ENOG410PMIA; InterPro:IPR015943,IPR011044; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_10535S BUSCO:EOG09262Q6S; COG:J; EggNog:ENOG410PH4P; InterPro:IPR001269,IPR018517,IPR035587,IPR013785; PFAM:PF01207; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0017150 - tRNA dihydrouridine synthase activity [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_process: GO:0008033 - tRNA processing [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_10536A COG:S; EggNog:ENOG410PSEG; InterPro:IPR009072,IPR018552; PFAM:PF09415; go_function: GO:0046982 - protein heterodimerization activity [Evidence IEA]; go_process: GO:0006281 - DNA repair [Evidence IEA]; go_process: GO:0051382 - kinetochore assembly [Evidence IEA] AKAW2_10537A COG:S; EggNog:ENOG410PNTE; InterPro:IPR002589,IPR043472; PFAM:PF01661 AKAW2_10538A COG:S; EggNog:ENOG410PNTE; InterPro:IPR001398,IPR014347; PFAM:PF01187 AKAW2_10539A COG:S; EggNog:ENOG410Q24J; InterPro:IPR040459; PFAM:PF04457 AKAW2_10540S BUSCO:EOG09264DY4; COG:S; EggNog:ENOG410PMW0; InterPro:IPR008685; PFAM:PF05859; go_component: GO:0000775 - chromosome, centromeric region [Evidence IEA]; go_component: GO:0005634 - nucleus [Evidence IEA]; go_process: GO:0000278 - mitotic cell cycle [Evidence IEA] AKAW2_10541A BUSCO:EOG092649QJ; COG:F; EggNog:ENOG410PGPI; InterPro:IPR004721,IPR006680,IPR002195,IPR032466; MEROPS:MER0061068; PFAM:PF01979; go_function: GO:0004151 - dihydroorotase activity [Evidence IEA]; go_function: GO:0016787 - hydrolase activity [Evidence IEA]; go_function: GO:0016812 - hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides [Evidence IEA]; go_process: GO:0019856 - pyrimidine nucleobase biosynthetic process [Evidence IEA] AKAW2_10543A COG:Q; EggNog:ENOG410PIXU; InterPro:IPR015889,IPR000627; PFAM:PF00775; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0008199 - ferric iron binding [Evidence IEA]; go_function: GO:0016702 - oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [Evidence IEA]; go_process: GO:0006725 - cellular aromatic compound metabolic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_10542S COG:S; EggNog:ENOG410PRUF; TransMembrane:4 (i39-63o83-109i121-143o215-238i) AKAW2_10545A COG:Q; EggNog:ENOG410PJFX; InterPro:IPR036291,IPR002347,IPR020904; PFAM:PF13561; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_10546S COG:K; EggNog:ENOG410PN3P; InterPro:IPR011421,IPR027124; PFAM:PF07572 AKAW2_10548A COG:A; EggNog:ENOG410PHXQ; InterPro:IPR018188,IPR033697,IPR001568,IPR033130, IPR036430; PFAM:PF00445; SECRETED:SignalP(1-23); go_function: GO:0003723 - RNA binding [Evidence IEA]; go_function: GO:0033897 - ribonuclease T2 activity [Evidence IEA] AKAW2_10549S COG:K; EggNog:ENOG410QE18; InterPro:IPR000182,IPR016181; PFAM:PF13508,PF00583,PF08445; go_function: GO:0008080 - N-acetyltransferase activity [Evidence IEA] AKAW2_10550A COG:K; EggNog:ENOG410PSQP; InterPro:IPR036236,IPR013087; PFAM:PF00096 AKAW2_10552A COG:S; EggNog:ENOG410PHIS; InterPro:IPR033433,IPR032514,IPR014870; PFAM:PF17168,PF16335,PF08760; SECRETED:SignalP(1-19) AKAW2_10553S COG:S; EggNog:ENOG410PZWM AKAW2_10554A COG:J; EggNog:ENOG410PFQM; InterPro:IPR027417,IPR001650,IPR014014,IPR014001, IPR011545,IPR000629; PFAM:PF00270,PF00271; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0004386 - helicase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA] AKAW2_10555A COG:S; EggNog:ENOG410PYWD; SECRETED:SignalP(1-21) AKAW2_10556A BUSCO:EOG09260W52; COG:A; EggNog:ENOG410PHT3; InterPro:IPR003107,IPR011990,IPR008847; PFAM:PF05843; TransMembrane:1 (o679-697i); go_component: GO:0005634 - nucleus [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0006396 - RNA processing [Evidence IEA]; go_process: GO:0006397 - mRNA processing [Evidence IEA] AKAW2_10557S BUSCO:EOG09264COX; COG:B; EggNog:ENOG410PI2N; InterPro:IPR017282,IPR006818,IPR036747; PFAM:PF04729; go_component: GO:0005634 - nucleus [Evidence IEA]; go_function: GO:0042393 - histone binding [Evidence IEA]; go_process: GO:0006333 - chromatin assembly or disassembly [Evidence IEA]; go_process: GO:0006334 - nucleosome assembly [Evidence IEA]; go_process: GO:0006337 - nucleosome disassembly [Evidence IEA]; go_process: GO:0016573 - histone acetylation [Evidence IEA] AKAW2_10558A BUSCO:EOG09260931; COG:U; EggNog:ENOG410QDDC; InterPro:IPR013905,IPR036322,IPR015943,IPR011048, IPR019775,IPR001680; PFAM:PF00400,PF08596; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_10559A COG:S; EggNog:ENOG410PSQX; InterPro:IPR011009 AKAW2_10560A BUSCO:EOG09264829; COG:S; EggNog:ENOG410PJZB; InterPro:IPR004114,IPR040183; PFAM:PF02926; go_function: GO:0003723 - RNA binding [Evidence IEA]; go_process: GO:0006400 - tRNA modification [Evidence IEA] AKAW2_10561S COG:H; EggNog:ENOG410PHI5; InterPro:IPR012000,IPR011766,IPR029061,IPR029035; PFAM:PF02775,PF00205; go_function: GO:0000287 - magnesium ion binding [Evidence IEA]; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0030976 - thiamine pyrophosphate binding [Evidence IEA] AKAW2_10562S COG:T; EggNog:ENOG410PG0D; InterPro:IPR017441,IPR008271,IPR000719,IPR011009; PFAM:PF07714,PF00069; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_10563A COG:U; EggNog:ENOG410PKJA; InterPro:IPR007265; PFAM:PF04136; go_component: GO:0005801 - cis-Golgi network [Evidence IEA]; go_component: GO:0016020 - membrane [Evidence IEA]; go_process: GO:0006886 - intracellular protein transport [Evidence IEA] AKAW2_10564S COG:J; EggNog:ENOG410QDBB; InterPro:IPR009091,IPR000408; PFAM:PF13540,PF00415 AKAW2_10565S COG:E; EggNog:ENOG410PJ7Y; InterPro:IPR015424,IPR002129,IPR015421; PFAM:PF00282; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0016831 - carboxy-lyase activity [Evidence IEA]; go_function: GO:0030170 - pyridoxal phosphate binding [Evidence IEA]; go_process: GO:0019752 - carboxylic acid metabolic process [Evidence IEA] AKAW2_10566A COG:D,U; EggNog:ENOG410PI2T; InterPro:IPR007528,IPR042044; PFAM:PF04437; go_component: GO:0005783 - endoplasmic reticulum [Evidence IEA]; go_process: GO:0048193 - Golgi vesicle transport [Evidence IEA] AKAW2_10567S COG:L; EggNog:ENOG410PJZ1; InterPro:IPR012308,IPR012309,IPR036599,IPR012310, IPR016059,IPR000977,IPR012340; PFAM:PF04675,PF01068,PF04679; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0003909 - DNA ligase activity [Evidence IEA]; go_function: GO:0003910 - DNA ligase (ATP) activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006281 - DNA repair [Evidence IEA]; go_process: GO:0006310 - DNA recombination [Evidence IEA]; go_process: GO:0051103 - DNA ligation involved in DNA repair [Evidence IEA]; go_process: GO:0071897 - DNA biosynthetic process [Evidence IEA] AKAW2_10568A COG:S; EggNog:ENOG410PMUJ AKAW2_10570S COG:S; EggNog:ENOG410PHFV; InterPro:IPR021917,IPR036404,IPR001229; PFAM:PF12044 AKAW2_10571S COG:K; EggNog:ENOG410PJAG; InterPro:IPR007604; PFAM:PF04516 AKAW2_10572S SECRETED:SignalP(1-21); TransMembrane:1 (n6-17c21/22o239-256i) AKAW2_10573A BUSCO:EOG09260EQD; COG:U; EggNog:ENOG410PGI4; InterPro:IPR036322,IPR011990,IPR000547; PFAM:PF00637; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0006886 - intracellular protein transport [Evidence IEA]; go_process: GO:0016192 - vesicle-mediated transport [Evidence IEA] AKAW2_10574S COG:S; EggNog:ENOG410PMAF; InterPro:IPR003734; PFAM:PF02582; TransMembrane:1 (o400-418i) AKAW2_10575S COG:A; EggNog:ENOG410PHXQ; InterPro:IPR018188,IPR033697,IPR001568,IPR033130, IPR036430; PFAM:PF00445; go_function: GO:0003723 - RNA binding [Evidence IEA]; go_function: GO:0033897 - ribonuclease T2 activity [Evidence IEA] AKAW2_10576A COG:K; EggNog:ENOG410PJ87; InterPro:IPR036236,IPR013087; PFAM:PF00096 AKAW2_10577S COG:J; EggNog:ENOG410PN07; InterPro:IPR038582,IPR019956,IPR029071,IPR011332, IPR002906,IPR019954,IPR000626; PFAM:PF00240,PF14560,PF11976,PF01599; go_component: GO:0005840 - ribosome [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0006412 - translation [Evidence IEA] AKAW2_10578A CAZy:GH18; COG:G; EggNog:ENOG410PH2N; InterPro:IPR011583,IPR029070,IPR001223,IPR017853, IPR001579; PFAM:PF00704; go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_function: GO:0008061 - chitin binding [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_10579A COG:S; EggNog:ENOG410PIX1 AKAW2_10580A COG:O; EggNog:ENOG410PH7X; InterPro:IPR029055,IPR001353,IPR023332; MEROPS:MER0047593; PFAM:PF00227; go_component: GO:0005839 - proteasome core complex [Evidence IEA]; go_process: GO:0051603 - proteolysis involved in cellular protein catabolic process [Evidence IEA] AKAW2_10581A BUSCO:EOG092644DY; COG:S; EggNog:ENOG410PTB2; InterPro:IPR019327; PFAM:PF10180 AKAW2_10582A COG:Z; EggNog:ENOG410PIAW; InterPro:IPR007259,IPR041470,IPR042241,IPR040457; PFAM:PF04130,PF17681; go_component: GO:0000922 - spindle pole [Evidence IEA]; go_component: GO:0005815 - microtubule organizing center [Evidence IEA]; go_function: GO:0043015 - gamma-tubulin binding [Evidence IEA]; go_process: GO:0000226 - microtubule cytoskeleton organization [Evidence IEA]; go_process: GO:0007020 - microtubule nucleation [Evidence IEA] AKAW2_10583A COG:K; EggNog:ENOG410PIV6; InterPro:IPR004827,IPR020956,IPR002112,IPR021755, IPR021756; PFAM:PF00170,PF11785,PF11786,PF07716,PF11787; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0003700 - DNA-binding transcription factor activity [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_10584A COG:F; EggNog:ENOG410PRX6; InterPro:IPR014306,IPR036817,IPR023418,IPR023416; PFAM:PF00576; go_function: GO:0033971 - hydroxyisourate hydrolase activity [Evidence IEA]; go_process: GO:0006144 - purine nucleobase metabolic process [Evidence IEA] AKAW2_10585S BUSCO:EOG092631UM; COG:P; EggNog:ENOG410PG12; InterPro:IPR025723,IPR027417,IPR027542,IPR016300; PFAM:PF01656,PF02374,PF13614; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA] AKAW2_10586A COG:J; EggNog:ENOG410PISD; InterPro:IPR016650,IPR019010,IPR036390,IPR000717; PFAM:PF09440,PF01399; go_component: GO:0005737 - cytoplasm [Evidence IEA]; go_component: GO:0005852 - eukaryotic translation initiation factor 3 complex [Evidence IEA]; go_function: GO:0003743 - translation initiation factor activity [Evidence IEA] AKAW2_10587S COG:S; EggNog:ENOG410PTBJ; InterPro:IPR007740; PFAM:PF05046; go_component: GO:0005840 - ribosome [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_process: GO:0006412 - translation [Evidence IEA] AKAW2_10588A COG:K; EggNog:ENOG410QDPZ; InterPro:IPR036431,IPR001606; PFAM:PF01388; go_function: GO:0003677 - DNA binding [Evidence IEA] AKAW2_10590S COG:E; EggNog:ENOG410PU8G; InterPro:IPR024688,IPR018357,IPR011004,IPR001451; PFAM:PF14602,PF00132,PF12464; go_function: GO:0016407 - acetyltransferase activity [Evidence IEA]; go_function: GO:0016740 - transferase activity [Evidence IEA] AKAW2_10589A COG:S; EggNog:ENOG410PWGD; InterPro:IPR036864,IPR021858,IPR001138; PFAM:PF00172,PF11951; TransMembrane:1 (o392-409i); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_10591S COG:O; EggNog:ENOG410PGYA; InterPro:IPR003960,IPR003959,IPR027417,IPR003593, IPR032501,IPR035256,IPR005937; PFAM:PF16450,PF00004,PF07728,PF07724; go_component: GO:0005737 - cytoplasm [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016787 - hydrolase activity [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA]; go_function: GO:0036402 - proteasome-activating ATPase activity [Evidence IEA]; go_process: GO:0030163 - protein catabolic process [Evidence IEA] AKAW2_10592S COG:O; EggNog:ENOG410PFB5; InterPro:IPR021109,IPR033819,IPR001461,IPR001969, IPR033121; MEROPS:MER0000941; PFAM:PF00026,PF14543; SECRETED:SignalP(1-18); go_component: GO:0000324 - fungal-type vacuole [Evidence IEA]; go_function: GO:0004190 - aspartic-type endopeptidase activity [Evidence IEA]; go_process: GO:0006508 - proteolysis [Evidence IEA] AKAW2_10593S COG:K; EggNog:ENOG410PH1W; InterPro:IPR036420,IPR001357,IPR011947,IPR036412, IPR039189,IPR023214,IPR004274; PFAM:PF03031,PF00533; go_component: GO:0005634 - nucleus [Evidence IEA]; go_function: GO:0004721 - phosphoprotein phosphatase activity [Evidence IEA]; go_function: GO:0008420 - RNA polymerase II CTD heptapeptide repeat phosphatase activity [Evidence IEA]; go_process: GO:0070940 - dephosphorylation of RNA polymerase II C-terminal domain [Evidence IEA] AKAW2_10594A COG:S; EggNog:ENOG410PPT9; TransMembrane:4 (i20-42o54-76i81-100o152-171i) AKAW2_10595A BUSCO:EOG09263E87; COG:E; EggNog:ENOG410PFFU; InterPro:IPR020855,IPR023696,IPR014033,IPR006035; PFAM:PF00491; go_function: GO:0004053 - arginase activity [Evidence IEA]; go_function: GO:0016813 - hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines [Evidence IEA]; go_function: GO:0046872 - metal ion binding [Evidence IEA]; go_process: GO:0006525 - arginine metabolic process [Evidence IEA] AKAW2_10596A BUSCO:EOG09262MFL; COG:J; EggNog:ENOG410PFWQ; InterPro:IPR014746,IPR017958,IPR017959,IPR042114, IPR018027,IPR006075,IPR004413,IPR003789; PFAM:PF02934,PF02637; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0016874 - ligase activity [Evidence IEA]; go_function: GO:0016884 - carbon-nitrogen ligase activity, with glutamine as amido-N-donor [Evidence IEA] AKAW2_10597S COG:S; EggNog:ENOG410PNQ2; TransMembrane:3 (i422-443o449-468i480-498o) AKAW2_10598A COG:S; EggNog:ENOG410PH22 AKAW2_10599S COG:S; EggNog:ENOG410PK1G AKAW2_10600S COG:I; EggNog:ENOG410PJME; InterPro:IPR001753,IPR029045,IPR014748; PFAM:PF00378,PF16113; go_function: GO:0003824 - catalytic activity [Evidence IEA] AKAW2_10601S COG:S; EggNog:ENOG410QDUK; InterPro:IPR027417,IPR002182,IPR029058; PFAM:PF00931; go_function: GO:0043531 - ADP binding [Evidence IEA] AKAW2_10602S COG:S; EggNog:ENOG410PR6N AKAW2_10603S CAZy:CE10; COG:V; EggNog:ENOG410PIXW; InterPro:IPR002168,IPR033140,IPR029058,IPR013094; MEROPS:MER0034960; PFAM:PF07859; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_10605A COG:S; EggNog:ENOG410PT4N; TransMembrane:2 (i707-723o760-780i) AKAW2_10606A COG:U; EggNog:ENOG410PJTE; InterPro:IPR040040,IPR019460; PFAM:PF10377; go_process: GO:0000045 - autophagosome assembly [Evidence IEA]; go_process: GO:0000422 - autophagy of mitochondrion [Evidence IEA] AKAW2_10607S COG:S; EggNog:ENOG410PQD9; InterPro:IPR008426,IPR040034; PFAM:PF05837; go_component: GO:0000776 - kinetochore [Evidence IEA]; go_process: GO:0051382 - kinetochore assembly [Evidence IEA] AKAW2_10608S COG:K; EggNog:ENOG410PRUP; InterPro:IPR009071,IPR036910; PFAM:PF00505,PF09011 AKAW2_10609S COG:S; EggNog:ENOG410PP2J AKAW2_10610A COG:S; EggNog:ENOG410PMAE; InterPro:IPR025066; PFAM:PF13300 AKAW2_10611S BUSCO:EOG09263483; COG:E; EggNog:ENOG410PGAE; InterPro:IPR019811,IPR005106,IPR022697,IPR001342, IPR036291; PFAM:PF03447,PF00742; go_function: GO:0004412 - homoserine dehydrogenase activity [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0050661 - NADP binding [Evidence IEA]; go_process: GO:0006520 - cellular amino acid metabolic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_10612A COG:S; EggNog:ENOG410PFC5; InterPro:IPR021848; PFAM:PF11927; TransMembrane:1 (o12-33i) AKAW2_10613A COG:S; EggNog:ENOG410PYE6; TransMembrane:1 (o20-40i) AKAW2_10614A COG:S; EggNog:ENOG410PFHI; InterPro:IPR003864,IPR027815,IPR032880; PFAM:PF02714,PF14703,PF13967; TransMembrane:11 (o32-54i117-135o162-181i385-410o430-452i479-503o523- 540i547-564o594-621i648-668o674-693i); go_component: GO:0016020 - membrane [Evidence IEA] AKAW2_10615A BUSCO:EOG092635YY; COG:G; EggNog:ENOG410PGPF; InterPro:IPR000771,IPR006411,IPR013785; PFAM:PF01116; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0004332 - fructose-bisphosphate aldolase activity [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_function: GO:0016832 - aldehyde-lyase activity [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA]; go_process: GO:0006096 - glycolytic process [Evidence IEA] AKAW2_10616A COG:D,Z; EggNog:ENOG410Q2XJ AKAW2_10617A COG:D,Z; EggNog:ENOG410Q2XJ; InterPro:IPR009091,IPR000408; PFAM:PF13540,PF00415 AKAW2_10618A COG:O; EggNog:ENOG410PFRG; InterPro:IPR038765,IPR001394,IPR018200,IPR028889; MEROPS:MER0005855; PFAM:PF13423,PF00443; TransMembrane:1 (i7-27o); go_function: GO:0004843 - thiol-dependent ubiquitin-specific protease activity [Evidence IEA]; go_process: GO:0006511 - ubiquitin-dependent protein catabolic process [Evidence IEA]; go_process: GO:0016579 - protein deubiquitination [Evidence IEA] AKAW2_10619A BUSCO:EOG09262XGK; COG:E; EggNog:ENOG410PG8G; InterPro:IPR027281,IPR007698,IPR036291,IPR007886; PFAM:PF01262,PF05222; go_function: GO:0004754 - saccharopine dehydrogenase (NAD+, L-lysine-forming) activity [Evidence IEA]; go_process: GO:0009085 - lysine biosynthetic process [Evidence IEA] AKAW2_10621A COG:S; EggNog:ENOG410PRD2 AKAW2_10622S COG:S; EggNog:ENOG410PFMJ; InterPro:IPR041803,IPR009060,IPR003892; PFAM:PF02845; go_function: GO:0005515 - protein binding [Evidence IEA]; go_function: GO:0043130 - ubiquitin binding [Evidence IEA] AKAW2_10623S TransMembrane:1 (o103-124i) AKAW2_10624A COG:S; EggNog:ENOG410PUFJ; InterPro:IPR036864,IPR001138; PFAM:PF00172; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_10625S COG:S; EggNog:ENOG410PWUB; InterPro:IPR007568; PFAM:PF04479; TransMembrane:7 (o20-39i46-68o80-99i120-142o154-177i198-216o231-250i); go_component: GO:0016021 - integral component of membrane [Evidence IEA] AKAW2_10626A COG:T; EggNog:ENOG410PH58; InterPro:IPR037239,IPR000648,IPR018494; PFAM:PF01237; go_function: GO:0008289 - lipid binding [Evidence IEA] AKAW2_10627S COG:G; EggNog:ENOG410PGZ4; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i71-96o108-127i139-158o164-186i198-222o228-247i289- 308o328-349i370-391o403-425i437-460o466-485i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_10628S CAZy:GH3; COG:G; EggNog:ENOG410PJPJ; InterPro:IPR036962,IPR036881,IPR001764,IPR016181, IPR017853,IPR000182; PFAM:PF13673,PF00933,PF13508,PF00583; go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_function: GO:0008080 - N-acetyltransferase activity [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_10629S COG:C; EggNog:ENOG410PFY0; InterPro:IPR036188,IPR037099,IPR003953,IPR003952, IPR027477,IPR014006,IPR011281,IPR015939; PFAM:PF02910,PF00890; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0016627 - oxidoreductase activity, acting on the CH-CH group of donors [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_process: GO:0006099 - tricarboxylic acid cycle [Evidence IEA]; go_process: GO:0022900 - electron transport chain [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_10630A COG:G; EggNog:ENOG410PGPU; InterPro:IPR005829,IPR005828,IPR003663,IPR036259, IPR020846; PFAM:PF00083,PF07690; TransMembrane:12 (i118-135o165-185i197-215o227-245i257-278o284-307i378- 401o413-435i442-464o470-488i509-529o541-560i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_10631S COG:S; EggNog:ENOG410PW6F; InterPro:IPR018866,IPR043145,IPR000433,IPR003347; PFAM:PF10497,PF00569; go_function: GO:0008270 - zinc ion binding [Evidence IEA] AKAW2_10632S COG:S; EggNog:ENOG410PJQH AKAW2_10633S BUSCO:EOG09264V2U; COG:L; EggNog:ENOG410PNZS; InterPro:IPR036397,IPR013520,IPR012337,IPR022894; PFAM:PF00929; go_function: GO:0000175 - 3'-5'-exoribonuclease activity [Evidence IEA]; go_function: GO:0003676 - nucleic acid binding [Evidence IEA] AKAW2_10634S COG:G; EggNog:ENOG410PHM1; InterPro:IPR036900,IPR016055,IPR005846,IPR005845, IPR005844,IPR005843,IPR005841,IPR016066; PFAM:PF00408,PF02879,PF02878,PF02880; go_function: GO:0000287 - magnesium ion binding [Evidence IEA]; go_function: GO:0016868 - intramolecular transferase activity, phosphotransferases [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA]; go_process: GO:0071704 - organic substance metabolic process [Evidence IEA] AKAW2_10635A COG:S; EggNog:ENOG410PKCI; InterPro:IPR004104,IPR000683,IPR036291; PFAM:PF02894,PF01408; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA] AKAW2_10636A COG:S; EggNog:ENOG410PT9Y; TransMembrane:1 (o319-341i) AKAW2_10637A BUSCO:EOG09264KO7; COG:Z; EggNog:ENOG410PUQ7; InterPro:IPR004953,IPR027328,IPR036133,IPR001715, IPR042180,IPR036872; PFAM:PF00307,PF03271; go_function: GO:0005515 - protein binding [Evidence IEA]; go_function: GO:0008017 - microtubule binding [Evidence IEA] AKAW2_10638A COG:S; EggNog:ENOG410PJ7H; InterPro:IPR001810,IPR036322,IPR015943,IPR001680, IPR036047,IPR019775,IPR020472,IPR017986; PFAM:PF00646,PF00400,PF12937; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_10639A COG:S; EggNog:ENOG410PH6Y; InterPro:IPR036291,IPR000683; PFAM:PF01408; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA] AKAW2_10640S COG:E; EggNog:ENOG410PHAW; InterPro:IPR002220,IPR013785; PFAM:PF00701; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0016829 - lyase activity [Evidence IEA] AKAW2_10641A COG:B; EggNog:ENOG410PNZZ; InterPro:IPR028651,IPR019787,IPR019786,IPR011011, IPR024610,IPR001965,IPR013083; PFAM:PF12998 AKAW2_10642S COG:S; EggNog:ENOG410PWY3; InterPro:IPR040410; TransMembrane:6 (i20-39o78-98i125-144o156-176i183-201o221-244i) AKAW2_10643S COG:S; EggNog:ENOG410PN9N; InterPro:IPR036397,IPR040151,IPR012337; go_function: GO:0003676 - nucleic acid binding [Evidence IEA] AKAW2_10644S COG:K; EggNog:ENOG410PRT8; InterPro:IPR004305,IPR016084; PFAM:PF03070 AKAW2_10645S COG:Z; EggNog:ENOG410PMJ4; InterPro:IPR001451,IPR011004; PFAM:PF00132 AKAW2_10646A CAZy:GT4; COG:M; EggNog:ENOG410PHGT; InterPro:IPR001296; PFAM:PF00534,PF13692 AKAW2_10647S COG:U; EggNog:ENOG410PGCD; InterPro:IPR005225,IPR027417,IPR041838,IPR006689; PFAM:PF04670,PF08477,PF00025,PF00071,PF01926, PF09439; go_function: GO:0003924 - GTPase activity [Evidence IEA]; go_function: GO:0005525 - GTP binding [Evidence IEA] AKAW2_10648S COG:S; EggNog:ENOG410PSY0; InterPro:IPR021331; PFAM:PF11160 AKAW2_10649A COG:E; EggNog:ENOG410PGGM; InterPro:IPR038071,IPR002629; PFAM:PF01717; go_function: GO:0003871 - 5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0009086 - methionine biosynthetic process [Evidence IEA] AKAW2_10650S COG:S; EggNog:ENOG410PS9J AKAW2_10651S COG:S; EggNog:ENOG410PS9J AKAW2_10652A COG:S; EggNog:ENOG410QEE0; InterPro:IPR019787,IPR019786,IPR037869,IPR011011, IPR001965,IPR011009,IPR013083; PFAM:PF00628; go_component: GO:0048188 - Set1C/COMPASS complex [Evidence IEA] AKAW2_10653S COG:S; EggNog:ENOG410Q2IT; InterPro:IPR027417 AKAW2_10654S COG:O; EggNog:ENOG410PW5X AKAW2_10655A COG:G; EggNog:ENOG410PM50; InterPro:IPR005829,IPR005828,IPR003663,IPR036259, IPR020846; PFAM:PF00083,PF07690; TransMembrane:10 (n4-19c28/29o52-70i77-97o103-123i135-155o167-188i259- 277o297-318i325-343o363-385i428-447o); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_10656S COG:K; EggNog:ENOG410PGE6; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; TransMembrane:2 (o383-406i633-652o); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_10657A COG:E; EggNog:ENOG410PNBR; InterPro:IPR006620,IPR005123; PFAM:PF13640; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0031418 - L-ascorbic acid binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_10658S COG:G; EggNog:ENOG410PVSJ; InterPro:IPR005829,IPR005828,IPR003663,IPR036259, IPR020846; PFAM:PF00083,PF07690; TransMembrane:11 (i20-44o64-87i99-118o124-149i161-182o194-215i285-305o325- 346i353-375o387-405i456-477o); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_10660S COG:K; EggNog:ENOG410PIFD; InterPro:IPR036236,IPR013087 AKAW2_10661S COG:K; EggNog:ENOG410PKHY; InterPro:IPR036388,IPR001766,IPR008984,IPR036390, IPR018122,IPR000253,IPR030456; PFAM:PF00250,PF00498; go_function: GO:0003700 - DNA-binding transcription factor activity [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_function: GO:0043565 - sequence-specific DNA binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_10662S SECRETED:SignalP(1-20) AKAW2_10664S COG:S; EggNog:ENOG410PN5J; InterPro:IPR007568; PFAM:PF04479; TransMembrane:7 (o16-36i45-62o82-105i117-141o153-176i206-226o241-261i); go_component: GO:0016021 - integral component of membrane [Evidence IEA] AKAW2_10665A CAZy:AA7; COG:C; EggNog:ENOG410PMJF; InterPro:IPR006094,IPR036318,IPR016166,IPR016167, IPR016169; PFAM:PF01565; SECRETED:SignalP(1-16); go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_function: GO:0071949 - FAD binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_10666S COG:S; EggNog:ENOG410PRRF AKAW2_10668S TransMembrane:2 (i39-56o68-93i) AKAW2_10667A COG:Q; EggNog:ENOG410QEHX; InterPro:IPR002937,IPR036188; PFAM:PF00070,PF01593,PF13450; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_10669A COG:K; EggNog:ENOG410PN62; InterPro:IPR017970,IPR001356,IPR009057; PFAM:PF00046; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_10670S COG:S; EggNog:ENOG410PXRS; TransMembrane:2 (i7-33o53-75i) AKAW2_10671A COG:S; EggNog:ENOG410PQFJ; InterPro:IPR029063 AKAW2_10672A COG:S; EggNog:ENOG410PU56; InterPro:IPR036610,IPR008914,IPR035810; PFAM:PF01161; SECRETED:SignalP(1-30) AKAW2_10673A COG:P; EggNog:ENOG410PICQ; InterPro:IPR002524,IPR036837,IPR027470,IPR027469; PFAM:PF01545,PF16916; TransMembrane:6 (i239-261o267-288i309-327o347-368i380-397o403-421i); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0008324 - cation transmembrane transporter activity [Evidence IEA]; go_process: GO:0006812 - cation transport [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_10674S COG:O; EggNog:ENOG410PPWX; InterPro:IPR036249,IPR000866; PFAM:PF00578; go_function: GO:0016209 - antioxidant activity [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_10675S COG:G; EggNog:ENOG410PM50; InterPro:IPR005829,IPR005828,IPR003663,IPR036259, IPR020846; PFAM:PF00083,PF07690; TransMembrane:11 (n5-16c21/22o45-66i78-97o103-124i136-160o172-191i259- 280o300-318i327-346o358-383i395-414o426-446i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_10676A COG:S; EggNog:ENOG410PK6M; InterPro:IPR006680,IPR032466,IPR032465; PFAM:PF04909; go_function: GO:0016787 - hydrolase activity [Evidence IEA]; go_function: GO:0016831 - carboxy-lyase activity [Evidence IEA] AKAW2_10677S COG:O; EggNog:ENOG410PG37; InterPro:IPR001841,IPR013083; PFAM:PF00097,PF17123,PF13639; TransMembrane:1 (o16-40i) AKAW2_10678A COG:K; EggNog:ENOG410PP1W; InterPro:IPR036864,IPR001138; PFAM:PF00172; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_10679A COG:S; EggNog:ENOG410QDZJ; InterPro:IPR036291; TransMembrane:2 (i152-173o240-260i) AKAW2_10680A COG:P; EggNog:ENOG410PGDX; InterPro:IPR005829,IPR005828,IPR020846,IPR036259; PFAM:PF07690; TransMembrane:11 (o90-109i116-137o143-164i185-209o221-241i267-289o309- 329i341-360o366-390i402-424o436-457i); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_10681S COG:S; EggNog:ENOG410PN6J; InterPro:IPR008775; PFAM:PF05721 AKAW2_10682S COG:S; EggNog:ENOG410PY4I; InterPro:IPR006675,IPR006674,IPR003607; PFAM:PF01966 AKAW2_10683A BUSCO:EOG09262E7I; COG:V; EggNog:ENOG410PHH0; InterPro:IPR029021,IPR026070,IPR003595,IPR020422, IPR029260,IPR016130,IPR000387,IPR000340; PFAM:PF14671,PF00782; go_function: GO:0004721 - phosphoprotein phosphatase activity [Evidence IEA]; go_function: GO:0004725 - protein tyrosine phosphatase activity [Evidence IEA]; go_function: GO:0008138 - protein tyrosine/serine/threonine phosphatase activity [Evidence IEA]; go_function: GO:0016791 - phosphatase activity [Evidence IEA]; go_process: GO:0006470 - protein dephosphorylation [Evidence IEA]; go_process: GO:0007096 - regulation of exit from mitosis [Evidence IEA]; go_process: GO:0016311 - dephosphorylation [Evidence IEA] AKAW2_10684S COG:S; EggNog:ENOG410Q5MY; SECRETED:SignalP(1-17) AKAW2_10685S COG:S; EggNog:ENOG410PRWM; InterPro:IPR015419; PFAM:PF09341 AKAW2_10686S COG:O; EggNog:ENOG410PN5P; InterPro:IPR029759,IPR000889,IPR036249,IPR029760; PFAM:PF00255; go_function: GO:0004602 - glutathione peroxidase activity [Evidence IEA]; go_process: GO:0006979 - response to oxidative stress [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_10687A COG:S; EggNog:ENOG410PJDZ; InterPro:IPR033956,IPR002848,IPR016069,IPR016068, IPR036081; PFAM:PF01997; go_function: GO:0003697 - single-stranded DNA binding [Evidence IEA]; go_function: GO:0003723 - RNA binding [Evidence IEA]; go_function: GO:0043565 - sequence-specific DNA binding [Evidence IEA]; go_process: GO:0016070 - RNA metabolic process [Evidence IEA] AKAW2_10688A BUSCO:EOG0926506U; COG:A; EggNog:ENOG410PMYK; InterPro:IPR036249,IPR004123; PFAM:PF02966; go_component: GO:0046540 - U4/U6 x U5 tri-snRNP complex [Evidence IEA]; go_process: GO:0000398 - mRNA splicing, via spliceosome [Evidence IEA] AKAW2_10689S COG:J; EggNog:ENOG410PQSK; InterPro:IPR002671,IPR038526; PFAM:PF01776; go_component: GO:0005840 - ribosome [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_process: GO:0006412 - translation [Evidence IEA] AKAW2_10690A COG:L; EggNog:ENOG410PG7T; InterPro:IPR012337,IPR036397,IPR013520,IPR034922; go_function: GO:0003676 - nucleic acid binding [Evidence IEA] AKAW2_10691S COG:L; EggNog:ENOG410PI0C; InterPro:IPR007751,IPR029058; PFAM:PF05057; TransMembrane:1 (o278-299i) AKAW2_10692A COG:G; EggNog:ENOG410PHS3; InterPro:IPR036412,IPR006357,IPR006353,IPR023214; PFAM:PF13242,PF13344 AKAW2_10693A COG:S; EggNog:ENOG410Q073; InterPro:IPR008427; PFAM:PF05730; SECRETED:SignalP(1-25); TransMembrane:1 (n9-20c32/33o220-244i) AKAW2_10694A COG:S; EggNog:ENOG410PRTI; InterPro:IPR000612; PFAM:PF01679; TransMembrane:1 (o32-55i); go_component: GO:0016021 - integral component of membrane [Evidence IEA] AKAW2_10695S COG:C; EggNog:ENOG410PMYT; InterPro:IPR011555,IPR035921,IPR000245,IPR002379; PFAM:PF00137; TransMembrane:4 (o12-34i55-76o88-113i125-151o); go_component: GO:0033177 - proton-transporting two-sector ATPase complex, proton-transporting domain [Evidence IEA]; go_component: GO:0033179 - proton-transporting V-type ATPase, V0 domain [Evidence IEA]; go_function: GO:0015078 - proton transmembrane transporter activity [Evidence IEA]; go_process: GO:1902600 - proton transmembrane transport [Evidence IEA] AKAW2_10696A COG:S; EggNog:ENOG410PRE8; InterPro:IPR013177; PFAM:PF08213 AKAW2_10697A COG:D,T; EggNog:ENOG410PG0J; InterPro:IPR002975,IPR027417,IPR011025,IPR001019; PFAM:PF00503,PF00025; go_component: GO:0005834 - heterotrimeric G-protein complex [Evidence IEA]; go_function: GO:0001664 - G protein-coupled receptor binding [Evidence IEA]; go_function: GO:0003924 - GTPase activity [Evidence IEA]; go_function: GO:0005525 - GTP binding [Evidence IEA]; go_function: GO:0019001 - guanyl nucleotide binding [Evidence IEA]; go_function: GO:0031683 - G-protein beta/gamma-subunit complex binding [Evidence IEA]; go_process: GO:0007165 - signal transduction [Evidence IEA]; go_process: GO:0007186 - G protein-coupled receptor signaling pathway [Evidence IEA] AKAW2_10699S TransMembrane:1 (i101-122o) AKAW2_10700S COG:S; EggNog:ENOG410PTAV; InterPro:IPR011008,IPR009799; PFAM:PF07110; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA] AKAW2_10701A COG:E; EggNog:ENOG410PG5N; InterPro:IPR002293; PFAM:PF00324,PF13520; TransMembrane:12 (i32-48o68-92i113-137o157-177i189-210o230-251i263-288o316- 340i373-391o397-419i440-459o471-490i); go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_10702S COG:S; EggNog:ENOG410PWPT; InterPro:IPR036864,IPR021858,IPR001138; PFAM:PF00172,PF11951; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_10703S COG:S; EggNog:ENOG410PP8H; InterPro:IPR014710,IPR010424,IPR011051; PFAM:PF05899 AKAW2_10704S COG:H; EggNog:ENOG410PKM6; InterPro:IPR001613,IPR036188,IPR002937; PFAM:PF13450,PF01593; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_10705S COG:T; EggNog:ENOG410QDPV; InterPro:IPR000651,IPR036964,IPR023578,IPR008937, IPR001895; PFAM:PF00617,PF00618; go_function: GO:0005085 - guanyl-nucleotide exchange factor activity [Evidence IEA]; go_process: GO:0007264 - small GTPase mediated signal transduction [Evidence IEA] AKAW2_10706S COG:F; EggNog:ENOG410PI9B; InterPro:IPR002110,IPR037986,IPR036770,IPR002710, IPR020683; PFAM:PF01843,PF13857,PF12796,PF00023; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_10707S COG:S; EggNog:ENOG410PPPB AKAW2_10708A COG:S; EggNog:ENOG410PKY2; InterPro:IPR035969,IPR000195; PFAM:PF00566 AKAW2_10709A BUSCO:EOG092633QB; COG:D; EggNog:ENOG410PHCR; InterPro:IPR016024,IPR011989,IPR013878; PFAM:PF08569 AKAW2_10710S COG:K,O,T; EggNog:ENOG410PFG1; InterPro:IPR036236,IPR029063,IPR041698,IPR025799; PFAM:PF13649,PF08241,PF13847; go_function: GO:0016274 - protein-arginine N-methyltransferase activity [Evidence IEA]; go_process: GO:0018216 - peptidyl-arginine methylation [Evidence IEA] AKAW2_10711A COG:S; EggNog:ENOG410PPME; InterPro:IPR039875,IPR019339; PFAM:PF10197 AKAW2_10712S BUSCO:EOG09260NC6; COG:O; EggNog:ENOG410PIAG; InterPro:IPR039812,IPR041569,IPR003959,IPR003338, IPR029067,IPR027417,IPR003593,IPR003960,IPR009010, IPR004201; PFAM:PF17862,PF00004,PF07724,PF02933; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA]; go_process: GO:0035494 - SNARE complex disassembly [Evidence IEA] AKAW2_10714A COG:S; EggNog:ENOG410PQND; InterPro:IPR019371; PFAM:PF10241 AKAW2_10715A COG:T; EggNog:ENOG410PFP0; InterPro:IPR001610,IPR000014,IPR035965,IPR003594, IPR003661,IPR036890,IPR036097,IPR000700,IPR013656, IPR004358,IPR005467; PFAM:PF00512,PF02518,PF08448; go_function: GO:0000155 - phosphorelay sensor kinase activity [Evidence IEA]; go_function: GO:0016772 - transferase activity, transferring phosphorus-containing groups [Evidence IEA]; go_process: GO:0007165 - signal transduction [Evidence IEA]; go_process: GO:0016310 - phosphorylation [Evidence IEA] AKAW2_10716S COG:T; EggNog:ENOG410QDVW; InterPro:IPR027417,IPR029016,IPR001789,IPR003594, IPR003661,IPR036890,IPR041664,IPR036097,IPR011006, IPR003018,IPR000719,IPR011009,IPR004358,IPR005467; PFAM:PF00072,PF00512,PF13185,PF13191,PF02518, PF01590; TransMembrane:2 (o1415-1436i1448-1467o); go_function: GO:0000155 - phosphorelay sensor kinase activity [Evidence IEA]; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016772 - transferase activity, transferring phosphorus-containing groups [Evidence IEA]; go_process: GO:0000160 - phosphorelay signal transduction system [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA]; go_process: GO:0007165 - signal transduction [Evidence IEA]; go_process: GO:0016310 - phosphorylation [Evidence IEA] AKAW2_10717A COG:F; EggNog:ENOG410PFHD; InterPro:IPR008979,IPR005164,IPR015908; PFAM:PF03561; go_function: GO:0004037 - allantoicase activity [Evidence IEA]; go_process: GO:0000256 - allantoin catabolic process [Evidence IEA] AKAW2_10718A COG:S; EggNog:ENOG410Q2S0 AKAW2_10719S COG:S; EggNog:ENOG410Q2PT; InterPro:IPR002110,IPR020683,IPR036047,IPR036770; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_10720S COG:Q; EggNog:ENOG410PWWV; InterPro:IPR000627,IPR015889; SECRETED:SignalP(1-18); go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0008199 - ferric iron binding [Evidence IEA]; go_function: GO:0016702 - oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [Evidence IEA]; go_process: GO:0006725 - cellular aromatic compound metabolic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_10721S COG:I; EggNog:ENOG410PN99; InterPro:IPR005079; MEROPS:MER0004220; PFAM:PF03417 AKAW2_10723S COG:S; EggNog:ENOG410PN16; InterPro:IPR006593; PFAM:PF03188; TransMembrane:6 (i42-65o71-93i105-127o147-166i187-207o213-232i) AKAW2_10724S COG:J; EggNog:ENOG410PHEH; InterPro:IPR006195,IPR015866,IPR042103,IPR010978, IPR002317,IPR002314; PFAM:PF02403,PF00587; go_function: GO:0000166 - nucleotide binding [Evidence IEA]; go_function: GO:0004812 - aminoacyl-tRNA ligase activity [Evidence IEA]; go_function: GO:0004828 - serine-tRNA ligase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006418 - tRNA aminoacylation for protein translation [Evidence IEA]; go_process: GO:0006434 - seryl-tRNA aminoacylation [Evidence IEA] AKAW2_10725A COG:S; EggNog:ENOG410PIVX; InterPro:IPR000210; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_10726S COG:S; EggNog:ENOG410PQHU; InterPro:IPR036864,IPR021858,IPR001138; PFAM:PF00172,PF11951; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_10727A COG:T; EggNog:ENOG410PGTT; InterPro:IPR017441,IPR008271,IPR039046,IPR000719, IPR011009; PFAM:PF07714,PF00069; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0004674 - protein serine/threonine kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_10730A COG:H; EggNog:ENOG410PHSQ; InterPro:IPR036188; PFAM:PF01593,PF13450 AKAW2_10731S COG:E,G; EggNog:ENOG410PGHJ; TransMembrane:1 (o36-57i) AKAW2_10732S COG:E,G; EggNog:ENOG410PGHJ; InterPro:IPR004853; PFAM:PF03151; TransMembrane:9 (i24-41o47-70i82-99o105-129i141-160o175-196i203-223o229- 247i276-298o) AKAW2_10733S COG:S; EggNog:ENOG410PP2V AKAW2_10734S TransMembrane:2 (i12-34o46-67i) AKAW2_10735A COG:G; EggNog:ENOG410Q223; InterPro:IPR005829,IPR005828,IPR003663,IPR036259, IPR020846; PFAM:PF00083,PF07690; TransMembrane:11 (i12-33o53-75i87-105o111-131i143-162o177-196i300-321o333- 352i364-388o400-418i430-449o); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_10736A BUSCO:EOG092613QA; COG:K; EggNog:ENOG410PFE5; InterPro:IPR013150,IPR036915,IPR011665,IPR000812, IPR029529,IPR013763; PFAM:PF07741,PF00382; go_component: GO:0000126 - transcription factor TFIIIB complex [Evidence IEA]; go_function: GO:0000995 - RNA polymerase III general transcription initiation factor activity [Evidence IEA]; go_function: GO:0017025 - TBP-class protein binding [Evidence IEA]; go_process: GO:0006352 - DNA-templated transcription, initiation [Evidence IEA]; go_process: GO:0006383 - transcription by RNA polymerase III [Evidence IEA]; go_process: GO:0070897 - transcription preinitiation complex assembly [Evidence IEA] AKAW2_10737S COG:P; EggNog:ENOG410Q1HB; InterPro:IPR018303,IPR023298,IPR023299,IPR036163, IPR036412,IPR001757,IPR017969,IPR006121,IPR027256, IPR008250,IPR023214; PFAM:PF00403,PF00702,PF00122; TransMembrane:8 (i468-493o517-537i558-585o597-614i766-789o809-837i1174- 1196o1220-1242i); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0000166 - nucleotide binding [Evidence IEA]; go_function: GO:0019829 - ATPase-coupled cation transmembrane transporter activity [Evidence IEA]; go_function: GO:0046872 - metal ion binding [Evidence IEA]; go_process: GO:0006812 - cation transport [Evidence IEA]; go_process: GO:0030001 - metal ion transport [Evidence IEA] AKAW2_10738A COG:L; EggNog:ENOG410PIJ7; InterPro:IPR027421,IPR011335,IPR006166,IPR036388; PFAM:PF02732; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0004518 - nuclease activity [Evidence IEA] AKAW2_10739S COG:S; EggNog:ENOG410PJJS; InterPro:IPR021709; PFAM:PF11696; TransMembrane:2 (i162-191o352-375i) AKAW2_10740A COG:M; EggNog:ENOG410PGXW; InterPro:IPR036291,IPR001509; PFAM:PF04321,PF01073,PF01370; go_function: GO:0003824 - catalytic activity [Evidence IEA] AKAW2_10741S COG:S; EggNog:ENOG410PICM; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_10743A COG:S; EggNog:ENOG410PQDH; TransMembrane:1 (o448-467i) AKAW2_10744S COG:S; EggNog:ENOG410PRMG AKAW2_10745S COG:O; EggNog:ENOG410Q07F; InterPro:IPR036291,IPR008030; PFAM:PF05368 AKAW2_10747A BUSCO:EOG0926142Y; COG:S; EggNog:ENOG410PFA8; InterPro:IPR015374,IPR011990; PFAM:PF09295; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_10748S COG:K; EggNog:ENOG410PHS4; InterPro:IPR033053; go_process: GO:0006336 - DNA replication-independent nucleosome assembly [Evidence IEA] AKAW2_10749A COG:Z; EggNog:ENOG410PGNR; InterPro:IPR036961,IPR027417,IPR027640,IPR001752; PFAM:PF00225,PF16796; go_function: GO:0003777 - microtubule motor activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0008017 - microtubule binding [Evidence IEA]; go_process: GO:0007018 - microtubule-based movement [Evidence IEA] AKAW2_10750S COG:S; EggNog:ENOG410PMQ5; InterPro:IPR007568; PFAM:PF04479; TransMembrane:7 (o23-41i53-73o79-102i122-145o160-179i199-216o244-264i); go_component: GO:0016021 - integral component of membrane [Evidence IEA] AKAW2_10751S COG:O; EggNog:ENOG410PPYQ; InterPro:IPR016135,IPR000608; PFAM:PF00179 AKAW2_10752S COG:Q; EggNog:ENOG410PW5A; InterPro:IPR001128,IPR017972,IPR002401,IPR036396; PFAM:PF00067; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_10753S COG:U; EggNog:ENOG410PFC7; InterPro:IPR035969,IPR000195; PFAM:PF00566 AKAW2_10754S COG:I; EggNog:ENOG410PHF7; InterPro:IPR007603; PFAM:PF04515; TransMembrane:12 (i93-114o142-162i169-191o197-217i238-268o288-305i312- 328o348-367i379-400o406-424i445-470o482-503i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_10755A SECRETED:SignalP(1-15); TransMembrane:1 (n4-15c22/23o347-367i) AKAW2_10756A COG:S; EggNog:ENOG410PU4S; TransMembrane:1 (o584-608i) AKAW2_10757A COG:O; EggNog:ENOG410PG2M; InterPro:IPR014851,IPR003959,IPR003960,IPR027417, IPR003593; PFAM:PF08740,PF00004; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA] AKAW2_10758S COG:S; EggNog:ENOG410PICU; InterPro:IPR024884,IPR036866,IPR001279; PFAM:PF13483,PF12706; SECRETED:SignalP(1-26); go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_function: GO:0070290 - N-acylphosphatidylethanolamine-specific phospholipase D activity [Evidence IEA] AKAW2_10760S COG:O; EggNog:ENOG410PGNN; InterPro:IPR002423,IPR027410,IPR027413,IPR017998, IPR002194,IPR012719,IPR027409; PFAM:PF00118; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0051082 - unfolded protein binding [Evidence IEA]; go_process: GO:0006457 - protein folding [Evidence IEA] AKAW2_10761A COG:S; EggNog:ENOG410PQ3T; InterPro:IPR009548; PFAM:PF06658; go_function: GO:0003725 - double-stranded RNA binding [Evidence IEA] AKAW2_10762S COG:O; EggNog:ENOG410QE85; InterPro:IPR016135,IPR000608; PFAM:PF00179 AKAW2_10763S COG:S; EggNog:ENOG410PSUB; InterPro:IPR036957,IPR001510; PFAM:PF00645; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA] AKAW2_10764A COG:G; EggNog:ENOG410QDY1; InterPro:IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i55-71o91-110i122-140o152-170i182-204o210-231i324- 350o370-390i411-430o436-454i466-489o504-527i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_10765S COG:E; EggNog:ENOG410PH30; InterPro:IPR006076,IPR036188; PFAM:PF01266; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_10766S COG:S; EggNog:ENOG410PPXY; TransMembrane:2 (i290-308o314-336i) AKAW2_10767S COG:S; EggNog:ENOG410PSZE AKAW2_10768S COG:S; EggNog:ENOG410PQKN; SECRETED:SignalP(1-21) AKAW2_10769S COG:S; EggNog:ENOG410PS58; InterPro:IPR000719,IPR011009; PFAM:PF00069; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_10770A COG:S; EggNog:ENOG410PMSZ; InterPro:IPR013907; PFAM:PF08598 AKAW2_10771A COG:S; EggNog:ENOG410PN8R AKAW2_10772A COG:S; EggNog:ENOG410PX68 AKAW2_10773S CAZy:GH72; COG:S; EggNog:ENOG410PHD0; InterPro:IPR017853,IPR004886; PFAM:PF03198; SECRETED:SignalP(1-27); TransMembrane:1 (n6-17c27/28o469-489i) AKAW2_10774A COG:T; EggNog:ENOG410PKMQ; InterPro:IPR000719,IPR011009,IPR001245; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_10775A TransMembrane:1 (i72-99o) AKAW2_10776A COG:S; EggNog:ENOG410Q2P0 AKAW2_10777A COG:L; EggNog:ENOG410PW8Z; InterPro:IPR017956; go_function: GO:0003677 - DNA binding [Evidence IEA] AKAW2_10778S COG:G; EggNog:ENOG410Q2XP; InterPro:IPR014718,IPR008183,IPR011013; PFAM:PF01263; SECRETED:SignalP(1-23); go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0016853 - isomerase activity [Evidence IEA]; go_function: GO:0030246 - carbohydrate binding [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_10779A COG:Z; EggNog:ENOG410PHP7; InterPro:IPR043129,IPR004000,IPR027127; PFAM:PF00022 AKAW2_10780S COG:S; EggNog:ENOG410QE0J; InterPro:IPR041177,IPR006086,IPR006084,IPR006085, IPR029060,IPR036279,IPR037316; PFAM:PF18380,PF00867,PF00752; go_function: GO:0004518 - nuclease activity [Evidence IEA]; go_function: GO:0008821 - crossover junction endodeoxyribonuclease activity [Evidence IEA] AKAW2_10781S COG:S; EggNog:ENOG410QE0J AKAW2_10782A BUSCO:EOG09263OD3; COG:I; EggNog:ENOG410PFIS; InterPro:IPR037997; TransMembrane:4 (i213-231o237-258i270-291o366-383i); go_function: GO:0004143 - diacylglycerol kinase activity [Evidence IEA] AKAW2_10783S COG:A; EggNog:ENOG410PIRE; InterPro:IPR025313,IPR027417,IPR001650,IPR014014, IPR014001,IPR011545,IPR000629; PFAM:PF00270,PF00271,PF13959; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0004386 - helicase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA] AKAW2_10784A COG:S; EggNog:ENOG410PXY6 AKAW2_10785A BUSCO:EOG092643JW; COG:J; EggNog:ENOG410PID3; InterPro:IPR009068,IPR005290,IPR000589; PFAM:PF00312; go_component: GO:0005840 - ribosome [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_process: GO:0006412 - translation [Evidence IEA] AKAW2_10786S COG:J; EggNog:ENOG410PGPW; InterPro:IPR001865,IPR032281,IPR023591,IPR005707, IPR018130,IPR027498; PFAM:PF16122; go_component: GO:0005840 - ribosome [Evidence IEA]; go_component: GO:0015935 - small ribosomal subunit [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_process: GO:0006412 - translation [Evidence IEA] AKAW2_10787A COG:S; EggNog:ENOG410PNCR; InterPro:IPR001806,IPR027417; PFAM:PF00071,PF08477; go_function: GO:0003924 - GTPase activity [Evidence IEA]; go_function: GO:0005525 - GTP binding [Evidence IEA] AKAW2_10788S BUSCO:EOG09263UAJ; COG:J; EggNog:ENOG410PIEK; InterPro:IPR020103,IPR020095,IPR001406,IPR020097; PFAM:PF01416; go_function: GO:0003723 - RNA binding [Evidence IEA]; go_function: GO:0009982 - pseudouridine synthase activity [Evidence IEA]; go_process: GO:0001522 - pseudouridine synthesis [Evidence IEA]; go_process: GO:0009451 - RNA modification [Evidence IEA] AKAW2_10789A COG:G; EggNog:ENOG410PQ61; InterPro:IPR019328; PFAM:PF10181; TransMembrane:3 (o32-54i66-82o88-106i); go_function: GO:0017176 - phosphatidylinositol N-acetylglucosaminyltransferase activity [Evidence IEA] AKAW2_10790S COG:F; EggNog:ENOG410PGS4; InterPro:IPR029057,IPR000836,IPR029099,IPR005946; PFAM:PF00156,PF14572,PF13793; go_function: GO:0000287 - magnesium ion binding [Evidence IEA]; go_function: GO:0004749 - ribose phosphate diphosphokinase activity [Evidence IEA]; go_process: GO:0009116 - nucleoside metabolic process [Evidence IEA]; go_process: GO:0009165 - nucleotide biosynthetic process [Evidence IEA] AKAW2_10791A COG:C; EggNog:ENOG410PJN9; InterPro:IPR016727,IPR036079,IPR002843; PFAM:PF01992; go_component: GO:0033179 - proton-transporting V-type ATPase, V0 domain [Evidence IEA]; go_function: GO:0015078 - proton transmembrane transporter activity [Evidence IEA]; go_process: GO:1902600 - proton transmembrane transport [Evidence IEA] AKAW2_10792S COG:A; EggNog:ENOG410PIKN; InterPro:IPR012976,IPR012974,IPR002687,IPR036070, IPR029012,IPR042239; PFAM:PF08156,PF01798 AKAW2_10793A CAZy:AA3; CAZy:AA8; COG:E; EggNog:ENOG410PKE9; InterPro:IPR012132,IPR036188,IPR000172,IPR007867; PFAM:PF05199,PF00732; SECRETED:SignalP(1-26); go_function: GO:0016614 - oxidoreductase activity, acting on CH-OH group of donors [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_10794S COG:S; EggNog:ENOG410PWUC AKAW2_10795S COG:S; EggNog:ENOG410Q0CJ; InterPro:IPR038846,IPR038324; go_component: GO:0005666 - RNA polymerase III complex [Evidence IEA]; go_process: GO:0006384 - transcription initiation from RNA polymerase III promoter [Evidence IEA] AKAW2_10796A COG:S; EggNog:ENOG410PR79; TransMembrane:1 (i40-57o) AKAW2_10797A COG:S; EggNog:ENOG410PJ8B AKAW2_10798A COG:C; EggNog:ENOG410PHPJ; InterPro:IPR001972,IPR043202,IPR036013,IPR001107; MEROPS:MER0192051; PFAM:PF01145; go_component: GO:0005886 - plasma membrane [Evidence IEA]; go_component: GO:0016020 - membrane [Evidence IEA] AKAW2_10799S COG:S; EggNog:ENOG410PSDR; InterPro:IPR001810,IPR036047; PFAM:PF00646; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_10800S COG:S; EggNog:ENOG410PQYB; InterPro:IPR025204; PFAM:PF13092 AKAW2_10801A COG:P; EggNog:ENOG410PI9V; InterPro:IPR002645,IPR001902,IPR036513,IPR011547; PFAM:PF00916,PF01740; TransMembrane:12 (i118-135o141-159i171-191o221-244i256-275o309-326i347- 363o369-387i399-418o438-457i478-497o534-565i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0008271 - secondary active sulfate transmembrane transporter activity [Evidence IEA]; go_function: GO:0015116 - sulfate transmembrane transporter activity [Evidence IEA]; go_process: GO:0008272 - sulfate transport [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_10802S BUSCO:EOG09263CAH; COG:J; EggNog:ENOG410PJGU; InterPro:IPR012340,IPR022967,IPR003029,IPR044126, IPR011488,IPR024055,IPR024054; PFAM:PF00575,PF07541; antiSMASH:Cluster_1.12; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0003723 - RNA binding [Evidence IEA]; go_function: GO:0003743 - translation initiation factor activity [Evidence IEA] AKAW2_10803S COG:P; EggNog:ENOG410PGN6; InterPro:IPR013122,IPR024862; TransMembrane:8 (i232-252o264-282i294-316o336-354i375-393o435-456i490- 510o522-540i); antiSMASH:Cluster_1.12; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0005216 - ion channel activity [Evidence IEA]; go_process: GO:0006811 - ion transport [Evidence IEA] AKAW2_10804A COG:V; EggNog:ENOG410PIPX; InterPro:IPR001466,IPR012338; MEROPS:MER0011726; PFAM:PF00144; SMCOG1053:beta-lactamase; antiSMASH:Cluster_1.12 AKAW2_10805A COG:S; EggNog:ENOG410PFQR; antiSMASH:Cluster_1.12 AKAW2_10806S COG:Q; EggNog:ENOG410PFKE; InterPro:IPR001227,IPR016036,IPR014043,IPR016035; PFAM:PF00698; antiSMASH:Cluster_1.12; go_function: GO:0016740 - transferase activity [Evidence IEA] AKAW2_10807S COG:Q; EggNog:ENOG410PFKE; InterPro:IPR020807,IPR042104; antiSMASH:Cluster_1.12 AKAW2_10808S COG:Q; EggNog:ENOG410PFKE; InterPro:IPR020807,IPR042104; PFAM:PF14765; antiSMASH:Cluster_1.12 AKAW2_10809S COG:Q; EggNog:ENOG410PFKE; InterPro:IPR036291,IPR013968; antiSMASH:Cluster_1.12 AKAW2_10810S COG:Q; EggNog:ENOG410PFKE; InterPro:IPR020806,IPR036736,IPR009081; PFAM:PF00550; antiSMASH:Cluster_1.12; go_function: GO:0031177 - phosphopantetheine binding [Evidence IEA] AKAW2_10811S COG:Q; EggNog:ENOG410PH86; InterPro:IPR036291,IPR002347; PFAM:PF08659,PF00106,PF13561; SMCOG1001:short-chain dehydrogenase/reductase SDR; antiSMASH:Cluster_1.12; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_10812A COG:Q; EggNog:ENOG410PU85; InterPro:IPR001128,IPR002401,IPR036396; TransMembrane:1 (o44-66i); antiSMASH:Cluster_1.12; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_10813A COG:Q; EggNog:ENOG410PU85; InterPro:IPR001128,IPR036396; PFAM:PF00067; SECRETED:SignalP(1-19); SMCOG1034:cytochrome P450; antiSMASH:Cluster_1.12; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_10814S COG:Q; EggNog:ENOG410PFZD; InterPro:IPR016036,IPR016035,IPR001227,IPR014043, IPR016039,IPR032821,IPR014030,IPR014031,IPR020841; PFAM:PF16197,PF00109,PF02801,PF00698; SMCOG1022:Beta-ketoacyl synthase; antiSMASH:Cluster_1.12; go_function: GO:0016740 - transferase activity [Evidence IEA]; go_function: GO:0016746 - transferase activity, transferring acyl groups [Evidence IEA] AKAW2_10815S COG:Q; EggNog:ENOG410QD7U; InterPro:IPR016035,IPR001227,IPR029063,IPR013217, IPR020807,IPR042104,IPR011032,IPR020843; PFAM:PF14765,PF13649,PF13489,PF05401,PF01209, PF08242,PF08241,PF13847; SMCOG1028:crotonyl-CoA reductase / alcohol dehydrogenase; antiSMASH:Cluster_1.12; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0016740 - transferase activity [Evidence IEA] AKAW2_10816A COG:M; EggNog:ENOG410Q1EM; InterPro:IPR002110,IPR036770,IPR020683; PFAM:PF13857,PF12796,PF00023,PF13637,PF13606; antiSMASH:Cluster_1.12; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_10817A BUSCO:EOG092629RT; COG:S; EggNog:ENOG410PG39; InterPro:IPR017455,IPR036531,IPR011011,IPR021565, IPR000306,IPR006642,IPR013087,IPR013083; PFAM:PF11464,PF01363; antiSMASH:Cluster_1.12; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0046872 - metal ion binding [Evidence IEA]; go_process: GO:0006281 - DNA repair [Evidence IEA] AKAW2_10818A COG:P; EggNog:ENOG410PFI2; InterPro:IPR018303,IPR023298,IPR023299,IPR001757, IPR036412,IPR008250,IPR023214,IPR006544; PFAM:PF00122,PF00702; SMCOG1037:heavy metal translocating P-type ATPase; TransMembrane:9 (o26-44i56-75o221-241i413-432o1051-1071i1078-1096o1116- 1136i1195-1215o1235-1253i); antiSMASH:Cluster_1.12; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0000166 - nucleotide binding [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA]; go_process: GO:0006812 - cation transport [Evidence IEA] AKAW2_10819A COG:S; EggNog:ENOG410PN1U; TransMembrane:7 (o12-32i44-67o87-109i121-141o171-191i203-223o243-265i); antiSMASH:Cluster_1.12 AKAW2_10820A COG:S; EggNog:ENOG410Q1TK; TransMembrane:7 (o24-49i61-83o103-124i136-156o176-200i212-235o255-273i) AKAW2_10821S COG:E; EggNog:ENOG410PMJG; InterPro:IPR002293; PFAM:PF13520; TransMembrane:6 (i31-48o68-89i175-196o202-220i241-261o273-291i); go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_10822A COG:G; EggNog:ENOG410PJIN; InterPro:IPR014830,IPR036497; PFAM:PF08718; go_component: GO:0005737 - cytoplasm [Evidence IEA]; go_function: GO:0120013 - lipid transfer activity [Evidence IEA]; go_process: GO:0120009 - intermembrane lipid transfer [Evidence IEA] AKAW2_10823A COG:B,K; EggNog:ENOG410PKNF; InterPro:IPR002589,IPR043472; PFAM:PF01661 AKAW2_10824A COG:K; EggNog:ENOG410PRGP; InterPro:IPR000679,IPR013088; PFAM:PF00320; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_function: GO:0043565 - sequence-specific DNA binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_10825A COG:T; EggNog:ENOG410PII6; InterPro:IPR019826,IPR002018,IPR029058; MEROPS:MER0030934; PFAM:PF00135; SECRETED:SignalP(1-18) AKAW2_10826S COG:S; EggNog:ENOG410QEAN; InterPro:IPR032710 AKAW2_10827A BUSCO:EOG09261DGU; COG:H; EggNog:ENOG410PFP6; InterPro:IPR014746,IPR004308; PFAM:PF03074; TransMembrane:1 (o463-485i); go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0004357 - glutamate-cysteine ligase activity [Evidence IEA]; go_process: GO:0006750 - glutathione biosynthetic process [Evidence IEA] AKAW2_10829A COG:C; EggNog:ENOG410PQX2; InterPro:IPR008698; PFAM:PF05676; go_component: GO:0005739 - mitochondrion [Evidence IEA]; go_function: GO:0003954 - NADH dehydrogenase activity [Evidence IEA]; go_function: GO:0008137 - NADH dehydrogenase (ubiquinone) activity [Evidence IEA] AKAW2_10830S COG:K; EggNog:ENOG410PGHG; InterPro:IPR018004,IPR002110,IPR036887,IPR020683, IPR029793,IPR036770,IPR003163; PFAM:PF00023,PF13637,PF13606; go_component: GO:0030907 - MBF transcription complex [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0000083 - regulation of transcription involved in G1/S transition of mitotic cell cycle [Evidence IEA] AKAW2_10832S COG:K; EggNog:ENOG410PVXP; InterPro:IPR036864,IPR021858,IPR001138; PFAM:PF00172,PF11951; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_10833A COG:E; EggNog:ENOG410PJF5; InterPro:IPR002293; PFAM:PF00324,PF13520; TransMembrane:12 (i47-68o88-109i130-149o183-202i209-231o257-275i296- 316o347-376i397-416o422-444i464-482o494-513i); go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_10834S COG:I; EggNog:ENOG410PKE2; InterPro:IPR026255,IPR008142,IPR007698,IPR036291, IPR024605,IPR008143,IPR007886,IPR029035,IPR034300; PFAM:PF02233,PF01262,PF05222,PF12769; TransMembrane:13 (n3-12c16/17o513-534i541-563o569-588i608-628o634-652i659- 678o684-703i715-735o747-768i789-806o812-830i842-860o866- 888i); go_function: GO:0008746 - NAD(P)+ transhydrogenase activity [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA]; go_process: GO:1902600 - proton transmembrane transport [Evidence IEA] AKAW2_10837A COG:S; EggNog:ENOG410Q2TG AKAW2_10838A COG:S; EggNog:ENOG410PU0E AKAW2_10839A COG:S; EggNog:ENOG410Q1SK AKAW2_10840A COG:S; EggNog:ENOG410Q8QX AKAW2_10841A SECRETED:SignalP(1-20) AKAW2_10842A COG:I; EggNog:ENOG410PGGA; InterPro:IPR030457,IPR002076; PFAM:PF01151; TransMembrane:5 (o54-72i84-103o182-202i222-240o260-281i); go_component: GO:0016021 - integral component of membrane [Evidence IEA] AKAW2_10843S BUSCO:EOG0926522L; COG:C; EggNog:ENOG410PPDG; InterPro:IPR036545,IPR003204; PFAM:PF02284; go_component: GO:0005743 - mitochondrial inner membrane [Evidence IEA]; go_function: GO:0004129 - cytochrome-c oxidase activity [Evidence IEA] AKAW2_10844A CAZy:GT15; COG:G; EggNog:ENOG410PIMR; InterPro:IPR029044,IPR002685; PFAM:PF01793; SECRETED:SignalP(1-32); go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0000030 - mannosyltransferase activity [Evidence IEA]; go_process: GO:0006486 - protein glycosylation [Evidence IEA] AKAW2_10845S COG:Z; EggNog:ENOG410PFIT; InterPro:IPR007259,IPR041470,IPR042241,IPR040457; PFAM:PF04130,PF17681; go_component: GO:0000922 - spindle pole [Evidence IEA]; go_component: GO:0005815 - microtubule organizing center [Evidence IEA]; go_function: GO:0043015 - gamma-tubulin binding [Evidence IEA]; go_process: GO:0000226 - microtubule cytoskeleton organization [Evidence IEA]; go_process: GO:0007020 - microtubule nucleation [Evidence IEA] AKAW2_10846A COG:F; EggNog:ENOG410PHVU; InterPro:IPR010073,IPR041609,IPR010918,IPR036676, IPR029062,IPR017926,IPR036604,IPR040707,IPR036921; MEROPS:MER0042827; PFAM:PF18072,PF13507,PF18076,PF02769; go_function: GO:0004642 - phosphoribosylformylglycinamidine synthase activity [Evidence IEA]; go_process: GO:0006189 - 'de novo' IMP biosynthetic process [Evidence IEA] AKAW2_10847S COG:G; EggNog:ENOG410PFTW; InterPro:IPR036259; TransMembrane:2 (i87-107o127-147i) AKAW2_10848S COG:G; EggNog:ENOG410PFTW; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; SECRETED:SignalP(1-25); TransMembrane:10 (i12-33o39-57i64-83o95-120i165-190o210-229i250-271o277- 298i310-331o343-364i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_10849S COG:S; EggNog:ENOG410PX5S; InterPro:IPR036610,IPR008914; PFAM:PF01161 AKAW2_10850S COG:K; EggNog:ENOG410PKPQ; InterPro:IPR036864,IPR007219,IPR004507,IPR001138; PFAM:PF00172,PF04082; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_10851A COG:G; EggNog:ENOG410PH6P; InterPro:IPR015377,IPR036462,IPR036663,IPR011234, IPR005959; PFAM:PF09298,PF01557; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0004334 - fumarylacetoacetase activity [Evidence IEA]; go_process: GO:0009072 - aromatic amino acid family metabolic process [Evidence IEA] AKAW2_10852A COG:S; EggNog:ENOG410Q28I; InterPro:IPR004827; go_function: GO:0003700 - DNA-binding transcription factor activity [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_10854A COG:Q; EggNog:ENOG410PI19; InterPro:IPR036396,IPR001128,IPR017972,IPR002401; PFAM:PF00067; TransMembrane:1 (o257-279i); go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_10855A CAZy:GT90; COG:S; EggNog:ENOG410PMW2; InterPro:IPR006598; PFAM:PF05686; TransMembrane:1 (i17-36o); antiSMASH:Cluster_1.13 AKAW2_10856A antiSMASH:Cluster_1.13 AKAW2_10857A COG:Q; EggNog:ENOG410PKKR; InterPro:IPR017871,IPR027417,IPR003593,IPR011527, IPR003439,IPR036640; PFAM:PF00005,PF00664; SMCOG1288:ABC transporter related protein; TransMembrane:15 (o32-51i72-93o105-123i135-155o161-179i311-335o409-431i498- 518o530-551i870-893o913-944i989-1010o1016-1036i1103- 1124o1130-1150i); antiSMASH:Cluster_1.13; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA]; go_function: GO:0042626 - ATPase-coupled transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_10858A COG:G; EggNog:ENOG410PMK1; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; SMCOG1005:Drug resistance transporter, EmrB/QacA; TransMembrane:14 (i29-57o69-89i96-116o122-143i150-173o185-205i226-248o254- 276i297-319o331-351i363-382o394-414i426-450o499-518i); antiSMASH:Cluster_1.13; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_10859A COG:S; EggNog:ENOG410PWWN; antiSMASH:Cluster_1.13 AKAW2_10860S COG:I; EggNog:ENOG410PNHB; InterPro:IPR029058,IPR013094; PFAM:PF07859; antiSMASH:Cluster_1.13; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_10861A COG:I; EggNog:ENOG410QDSG; InterPro:IPR000873,IPR009081,IPR036736,IPR029058, IPR001031,IPR020806,IPR042099; PFAM:PF00501,PF00550,PF00975; SMCOG1002:AMP-dependent synthetase and ligase; antiSMASH:Cluster_1.13; go_function: GO:0016788 - hydrolase activity, acting on ester bonds [Evidence IEA]; go_function: GO:0031177 - phosphopantetheine binding [Evidence IEA]; go_process: GO:0009058 - biosynthetic process [Evidence IEA] AKAW2_10862S COG:I; EggNog:ENOG410PFKD; InterPro:IPR023606,IPR003673; PFAM:PF02515; SMCOG1189:L-carnitine dehydratase/bile acid-inducible; antiSMASH:Cluster_1.13; go_function: GO:0008410 - CoA-transferase activity [Evidence IEA] AKAW2_10863S BUSCO:EOG09262DKA; COG:E; EggNog:ENOG410PVV7; InterPro:IPR004839,IPR015424,IPR015421,IPR015422; PFAM:PF00155; SMCOG1019:aminotransferase; antiSMASH:Cluster_1.13; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0030170 - pyridoxal phosphate binding [Evidence IEA]; go_process: GO:0009058 - biosynthetic process [Evidence IEA] AKAW2_10864S COG:G; EggNog:ENOG410QD9A; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; SMCOG1137:Major facilitator superfamily MFS 1; TransMembrane:12 (i45-66o86-108i115-134o140-161i173-196o208-226i247- 269o281-301i313-333o339-362i374-396o408-429i); antiSMASH:Cluster_1.13; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_10865S BUSCO:EOG09260S5R; COG:D; EggNog:ENOG410PG4I; InterPro:IPR013026,IPR019734,IPR011990; PFAM:PF13374,PF13432,PF12895; SMCOG1272:TPR repeat-containing protein; antiSMASH:Cluster_1.13; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_10866S BUSCO:EOG092655M5; COG:S; EggNog:ENOG410PHJD; InterPro:IPR007590,IPR043701; PFAM:PF04502; antiSMASH:Cluster_1.13; go_process: GO:0000398 - mRNA splicing, via spliceosome [Evidence IEA] AKAW2_10867A BUSCO:EOG092605T6; COG:B; EggNog:ENOG410QDJZ; InterPro:IPR016024,IPR003152,IPR003151,IPR033317, IPR011009,IPR014009,IPR000403; PFAM:PF00454,PF02259; antiSMASH:Cluster_1.13; go_component: GO:0000123 - histone acetyltransferase complex [Evidence IEA]; go_component: GO:0005634 - nucleus [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0016573 - histone acetylation [Evidence IEA] AKAW2_10868A BUSCO:EOG09261T98; COG:T; EggNog:ENOG410PFJ3; InterPro:IPR016024,IPR011989,IPR002554; PFAM:PF01603; go_component: GO:0000159 - protein phosphatase type 2A complex [Evidence IEA]; go_function: GO:0019888 - protein phosphatase regulator activity [Evidence IEA]; go_process: GO:0007165 - signal transduction [Evidence IEA] AKAW2_10869S BUSCO:EOG09263GSR; COG:K; EggNog:ENOG410PKPW; InterPro:IPR041499,IPR019136,IPR040454; PFAM:PF17682,PF09734; go_component: GO:0000127 - transcription factor TFIIIC complex [Evidence IEA]; go_process: GO:0006384 - transcription initiation from RNA polymerase III promoter [Evidence IEA] AKAW2_10870A COG:S; EggNog:ENOG410PP3M AKAW2_10871S COG:S; EggNog:ENOG410PTGN; InterPro:IPR012337,IPR036397,IPR002156; PFAM:PF00075; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0004523 - RNA-DNA hybrid ribonuclease activity [Evidence IEA] AKAW2_10872A COG:L; EggNog:ENOG410PGAC; InterPro:IPR012340,IPR027417,IPR001208,IPR041562, IPR033762,IPR031327,IPR008048,IPR018525; PFAM:PF00493,PF17855,PF17207,PF07728; go_component: GO:0005634 - nucleus [Evidence IEA]; go_component: GO:0042555 - MCM complex [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0003688 - DNA replication origin binding [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006260 - DNA replication [Evidence IEA]; go_process: GO:0006270 - DNA replication initiation [Evidence IEA]; go_process: GO:0032508 - DNA duplex unwinding [Evidence IEA] AKAW2_10873S BUSCO:EOG09260WCZ; COG:U; EggNog:ENOG410PGGC; InterPro:IPR039745,IPR012501; PFAM:PF07928; go_component: GO:0000938 - GARP complex [Evidence IEA]; go_process: GO:0042147 - retrograde transport, endosome to Golgi [Evidence IEA] AKAW2_10874A COG:S; EggNog:ENOG410Q2B6 AKAW2_10876S CAZy:GT3; COG:G; EggNog:ENOG410PJA3; InterPro:IPR008631; PFAM:PF05693; go_function: GO:0004373 - glycogen (starch) synthase activity [Evidence IEA]; go_process: GO:0005978 - glycogen biosynthetic process [Evidence IEA] AKAW2_10877S COG:P; EggNog:ENOG410PFME; InterPro:IPR015168,IPR027939; PFAM:PF09084; go_process: GO:0009228 - thiamine biosynthetic process [Evidence IEA] AKAW2_10878A COG:S; EggNog:ENOG410PHWY; InterPro:IPR039535,IPR011047; PFAM:PF05935,PF14269; SECRETED:SignalP(1-21); TransMembrane:1 (n5-16c21/22o529-554i) AKAW2_10879S COG:S; EggNog:ENOG410PJ5Y; InterPro:IPR008928; SECRETED:SignalP(1-23); go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_10880A BUSCO:EOG092633US; COG:H; EggNog:ENOG410PFX3; InterPro:IPR033749,IPR039702,IPR008949,IPR000092; PFAM:PF00348; go_function: GO:0016765 - transferase activity, transferring alkyl or aryl (other than methyl) groups [Evidence IEA]; go_process: GO:0008299 - isoprenoid biosynthetic process [Evidence IEA] AKAW2_10881S BUSCO:EOG092613S3; COG:D; EggNog:ENOG410PG1F; InterPro:IPR011990,IPR019734,IPR007192,IPR013026; PFAM:PF13432,PF04049,PF13176,PF13181,PF13414; go_component: GO:0005680 - anaphase-promoting complex [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0030071 - regulation of mitotic metaphase/anaphase transition [Evidence IEA] AKAW2_10882A COG:L; EggNog:ENOG410PMHH; InterPro:IPR012308,IPR029710,IPR036599,IPR012310; PFAM:PF04675,PF01068; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0003910 - DNA ligase (ATP) activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006281 - DNA repair [Evidence IEA]; go_process: GO:0006310 - DNA recombination [Evidence IEA]; go_process: GO:0051103 - DNA ligation involved in DNA repair [Evidence IEA] AKAW2_10883A COG:A; EggNog:ENOG410PGMT; InterPro:IPR031776,IPR036236,IPR031774,IPR022755, IPR021966,IPR024598,IPR013087; PFAM:PF11931,PF16837,PF12171,PF12108,PF12874; go_component: GO:0005681 - spliceosomal complex [Evidence IEA]; go_function: GO:0003723 - RNA binding [Evidence IEA]; go_process: GO:0000398 - mRNA splicing, via spliceosome [Evidence IEA] AKAW2_10884S COG:A; EggNog:ENOG410PHSA; InterPro:IPR027417,IPR001650,IPR014014,IPR014001, IPR011545,IPR000629; PFAM:PF00270,PF00271; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0004386 - helicase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA] AKAW2_10885A BUSCO:EOG0926312D; COG:H; EggNog:ENOG410PJ1V; InterPro:IPR036322,IPR015943,IPR001680,IPR006595, IPR017986; PFAM:PF00400; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_10887A COG:S; EggNog:ENOG410PK5T; InterPro:IPR037473,IPR018713; PFAM:PF09995; TransMembrane:2 (o371-390i460-484o) AKAW2_10888S BUSCO:EOG09261225; COG:C; EggNog:ENOG410PH6V; InterPro:IPR020003,IPR031686,IPR022878,IPR027417, IPR024034,IPR036121,IPR004100,IPR005725,IPR023366, IPR000194; PFAM:PF02874,PF16886,PF00006; go_component: GO:0033180 - proton-transporting V-type ATPase, V1 domain [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0046961 - proton-transporting ATPase activity, rotational mechanism [Evidence IEA]; go_process: GO:0046034 - ATP metabolic process [Evidence IEA]; go_process: GO:1902600 - proton transmembrane transport [Evidence IEA] AKAW2_10889S COG:U; EggNog:ENOG410PIAR; InterPro:IPR019762,IPR022812,IPR027417,IPR003130, IPR001401,IPR000375,IPR030381,IPR020850; PFAM:PF00350,PF01031,PF02212; go_function: GO:0003924 - GTPase activity [Evidence IEA]; go_function: GO:0005525 - GTP binding [Evidence IEA] AKAW2_10890A COG:E; EggNog:ENOG410PQMD; InterPro:IPR036526,IPR003010; PFAM:PF00795; go_process: GO:0006807 - nitrogen compound metabolic process [Evidence IEA] AKAW2_10891S COG:I; EggNog:ENOG410QDEJ; InterPro:IPR000073,IPR029058; MEROPS:MER0210990; PFAM:PF12697,PF12146,PF00561 AKAW2_10892S COG:S; EggNog:ENOG410PQQT; InterPro:IPR036851,IPR000028; PFAM:PF01328; TransMembrane:1 (i225-242o); go_function: GO:0004601 - peroxidase activity [Evidence IEA] AKAW2_10893S CAZy:GH16; COG:U; EggNog:ENOG410PJJN; InterPro:IPR000757,IPR013320; PFAM:PF00722; TransMembrane:1 (i68-86o); go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_10895S CAZy:GH43; COG:G; EggNog:ENOG410QDR4; InterPro:IPR016840,IPR023296,IPR006710; PFAM:PF04616; SECRETED:SignalP(1-15); go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_function: GO:0046558 - arabinan endo-1,5-alpha-L-arabinosidase activity [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_10896A COG:S; EggNog:ENOG410PHIK; InterPro:IPR011993,IPR029071,IPR001849,IPR000159; PFAM:PF00788,PF00169; go_process: GO:0007165 - signal transduction [Evidence IEA] AKAW2_10897A COG:S; EggNog:ENOG410PW3I AKAW2_10898S COG:S; EggNog:ENOG410Q1E6; TransMembrane:2 (i504-528o548-572i) AKAW2_10899A COG:E,I; EggNog:ENOG410QDQG; InterPro:IPR005913,IPR036291,IPR029903; PFAM:PF04321,PF01073,PF01370 AKAW2_10900S COG:C; EggNog:ENOG410PG19; InterPro:IPR016171,IPR006094,IPR036318,IPR004113, IPR016164,IPR016166,IPR016167,IPR016169; PFAM:PF02913,PF01565; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_function: GO:0071949 - FAD binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_10901S COG:Q; EggNog:ENOG410PP34; InterPro:IPR002347,IPR036291,IPR020904; PFAM:PF00106,PF13561,PF08659; SECRETED:SignalP(1-21); go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_10902A COG:S; EggNog:ENOG410PN18; InterPro:IPR001138; TransMembrane:3 (o165-184i204-221o281-299i); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_10903A COG:Q; EggNog:ENOG410PU77; InterPro:IPR001128,IPR017972,IPR002401,IPR036396; PFAM:PF00067; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_10904S COG:T; EggNog:ENOG410PF80; InterPro:IPR000719,IPR011009,IPR017441; PFAM:PF07714,PF00069; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_10905S COG:S; EggNog:ENOG410PFZV; InterPro:IPR025122; PFAM:PF13257 AKAW2_10906S COG:U; EggNog:ENOG410PQDK; InterPro:IPR039175; PFAM:PF02466; TransMembrane:1 (i50-72o); go_component: GO:0042721 - TIM22 mitochondrial import inner membrane insertion complex [Evidence IEA]; go_process: GO:0045039 - protein insertion into mitochondrial inner membrane [Evidence IEA] AKAW2_10907A COG:E; EggNog:ENOG410PJXH; InterPro:IPR036052,IPR001216,IPR001926; PFAM:PF00291; go_process: GO:0006535 - cysteine biosynthetic process from serine [Evidence IEA] AKAW2_10908S BUSCO:EOG09260LRX; COG:D; EggNog:ENOG410PH2X; InterPro:IPR027165,IPR011989,IPR025977,IPR016024; PFAM:PF12719; go_component: GO:0000796 - condensin complex [Evidence IEA]; go_process: GO:0007076 - mitotic chromosome condensation [Evidence IEA] AKAW2_10909S COG:S; EggNog:ENOG410Q18M; InterPro:IPR000504,IPR012337,IPR036443,IPR035979, IPR036397,IPR012677,IPR034351,IPR013520,IPR001876; PFAM:PF00641,PF00929,PF00076; go_function: GO:0003676 - nucleic acid binding [Evidence IEA] AKAW2_10910S COG:O; EggNog:ENOG410PFMY; InterPro:IPR029055,IPR001353,IPR023332; MEROPS:MER0004372; PFAM:PF00227; go_component: GO:0005839 - proteasome core complex [Evidence IEA]; go_process: GO:0051603 - proteolysis involved in cellular protein catabolic process [Evidence IEA] AKAW2_10911A COG:O; EggNog:ENOG410PPTJ; InterPro:IPR008913,IPR037274; PFAM:PF05495; go_function: GO:0008270 - zinc ion binding [Evidence IEA] AKAW2_10912S COG:U; EggNog:ENOG410PIQY; InterPro:IPR036322,IPR005135,IPR015943,IPR000300, IPR001680,IPR036691; PFAM:PF03372; TransMembrane:1 (o953-971i); go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0046856 - phosphatidylinositol dephosphorylation [Evidence IEA] AKAW2_10913S COG:G; EggNog:ENOG410PHZT; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; SMCOG1005:Drug resistance transporter, EmrB/QacA; TransMembrane:13 (i24-44o95-117i129-151o157-177i189-212o224-243i255- 274o309-331i343-367o373-393i400-421o441-461i473-493o); antiSMASH:Cluster_1.14; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_10914S COG:Q; EggNog:ENOG410PUEJ; InterPro:IPR001128,IPR017972,IPR002401,IPR036396; PFAM:PF00067; SMCOG1034:cytochrome P450; antiSMASH:Cluster_1.14; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_10915A COG:S; EggNog:ENOG410PQUC; InterPro:IPR021858; antiSMASH:Cluster_1.14 AKAW2_10916S COG:S; EggNog:ENOG410PY88; antiSMASH:Cluster_1.14 AKAW2_10917A COG:S; EggNog:ENOG410PN0P; InterPro:IPR000073,IPR029058; PFAM:PF12697; antiSMASH:Cluster_1.14 AKAW2_10918A COG:S; EggNog:ENOG410PXH0; TransMembrane:7 (o18-41i53-82o102-120i132-156o176-199i211-231o251-273i); antiSMASH:Cluster_1.14 AKAW2_10919S COG:T; EggNog:ENOG410PM0V; InterPro:IPR019819,IPR019826,IPR002018,IPR029058; MEROPS:MER0033188; PFAM:PF00135; SECRETED:SignalP(1-20); antiSMASH:Cluster_1.14 AKAW2_10920A COG:I; EggNog:ENOG410PVFD; InterPro:IPR016036,IPR016035,IPR016039,IPR018201, IPR042104,IPR014030,IPR011032,IPR013968,IPR001227, IPR032821,IPR014031,IPR006162,IPR014043,IPR020806, IPR020807,IPR020843,IPR020841,IPR009081,IPR029063, IPR036736,IPR036291,IPR013217,IPR013120; PFAM:PF16197,PF00109,PF07993,PF00550,PF13489, PF13649,PF01209,PF02801,PF00698,PF13847,PF14765,PF08659, PF01370,PF00106,PF08242,PF08241; SMCOG1022:Beta-ketoacyl synthase; antiSMASH:Cluster_1.14; go_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein] synthase activity [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0016740 - transferase activity [Evidence IEA]; go_function: GO:0016746 - transferase activity, transferring acyl groups [Evidence IEA]; go_function: GO:0031177 - phosphopantetheine binding [Evidence IEA]; go_process: GO:0006633 - fatty acid biosynthetic process [Evidence IEA] AKAW2_10921A COG:S; EggNog:ENOG410PP44; InterPro:IPR014710,IPR011051; TransMembrane:1 (o181-206i); antiSMASH:Cluster_1.14 AKAW2_10922S COG:Q; EggNog:ENOG410PHGJ; InterPro:IPR015798,IPR016182,IPR036460,IPR000269, IPR015802,IPR015800; PFAM:PF01179,PF02728,PF02727; antiSMASH:Cluster_1.14; go_function: GO:0005507 - copper ion binding [Evidence IEA]; go_function: GO:0008131 - primary amine oxidase activity [Evidence IEA]; go_function: GO:0048038 - quinone binding [Evidence IEA]; go_process: GO:0009308 - amine metabolic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_10923A COG:C; EggNog:ENOG410PHJW; InterPro:IPR044152,IPR001155,IPR013785; PFAM:PF00724; SMCOG1217:NADH:flavin oxidoreductase/NADH oxidase; antiSMASH:Cluster_1.14; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0003959 - NADPH dehydrogenase activity [Evidence IEA]; go_function: GO:0010181 - FMN binding [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0050661 - NADP binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_10924A COG:Q; EggNog:ENOG410PK2P; InterPro:IPR001128,IPR002401,IPR036396; PFAM:PF00067; SECRETED:SignalP(1-21); SMCOG1034:cytochrome P450; TransMembrane:1 (o12-37i); antiSMASH:Cluster_1.14; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_10925S COG:S; EggNog:ENOG410PTUB; TransMembrane:7 (o31-52i64-86o116-141i153-177o201-226i238-260o272-292i); antiSMASH:Cluster_1.14 AKAW2_10926S COG:Q; EggNog:ENOG410PUEQ; InterPro:IPR036291,IPR002347; PFAM:PF08659,PF00106,PF13561; SMCOG1001:short-chain dehydrogenase/reductase SDR; antiSMASH:Cluster_1.14; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_10927S COG:S; EggNog:ENOG410PH4N; InterPro:IPR036249,IPR036282,IPR010987,IPR004045; PFAM:PF13409,PF13417; antiSMASH:Cluster_1.14; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0006749 - glutathione metabolic process [Evidence IEA] AKAW2_10928A COG:S; EggNog:ENOG410PN18; InterPro:IPR001138,IPR036864; antiSMASH:Cluster_1.14; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_10929S COG:I; EggNog:ENOG410PFJU; InterPro:IPR002060,IPR006449,IPR008949,IPR033904; PFAM:PF00494; antiSMASH:Cluster_1.14; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0004310 - farnesyl-diphosphate farnesyltransferase activity [Evidence IEA]; go_function: GO:0016740 - transferase activity [Evidence IEA]; go_function: GO:0051996 - squalene synthase activity [Evidence IEA]; go_process: GO:0008610 - lipid biosynthetic process [Evidence IEA]; go_process: GO:0009058 - biosynthetic process [Evidence IEA] AKAW2_10930S COG:S; EggNog:ENOG410PY07; antiSMASH:Cluster_1.15 AKAW2_10931S COG:S; EggNog:ENOG410PY07; antiSMASH:Cluster_1.15 AKAW2_10932S COG:T; EggNog:ENOG410PKRQ; InterPro:IPR004839,IPR004838,IPR015424,IPR015421, IPR015422; PFAM:PF00155; SMCOG1019:aminotransferase; antiSMASH:Cluster_1.15; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0030170 - pyridoxal phosphate binding [Evidence IEA]; go_process: GO:0009058 - biosynthetic process [Evidence IEA] AKAW2_10933A COG:C; EggNog:ENOG410PGE5; InterPro:IPR001030,IPR018136,IPR006248,IPR036008, IPR015931,IPR015932,IPR015928,IPR000573; PFAM:PF00694,PF00330; go_function: GO:0003994 - aconitate hydratase activity [Evidence IEA]; go_function: GO:0051539 - 4 iron, 4 sulfur cluster binding [Evidence IEA]; go_process: GO:0006099 - tricarboxylic acid cycle [Evidence IEA] AKAW2_10934A COG:G; EggNog:ENOG410PKV4; InterPro:IPR005829,IPR005828,IPR003663,IPR036259, IPR020846; PFAM:PF00083,PF07690; TransMembrane:11 (o12-31i99-117o123-145i157-177o189-210i274-297o317- 337i344-362o374-399i411-435o441-461i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_10935A COG:S; EggNog:ENOG410PF8G; InterPro:IPR007400; PFAM:PF04303 AKAW2_10936A COG:K; EggNog:ENOG410PUUR; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; TransMembrane:1 (o515-534i); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_10937A COG:S; EggNog:ENOG410PRJP; InterPro:IPR006680,IPR032466; PFAM:PF04909; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_10938S COG:C; EggNog:ENOG410PHBV; InterPro:IPR018108,IPR023395; PFAM:PF00153 AKAW2_10939S COG:T; EggNog:ENOG410PFII; InterPro:IPR004813; PFAM:PF03169; TransMembrane:14 (o98-120i172-194o206-225i260-277o297-318i330-351o410- 431i467-485o491-517i577-599o645-663i675-691o697-714i721- 744o); go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_10940S COG:S; EggNog:ENOG410PWMA; InterPro:IPR036291,IPR008030; PFAM:PF13460,PF05368 AKAW2_10941S COG:G; EggNog:ENOG410PG7S; InterPro:IPR002241,IPR000111,IPR041233,IPR017853, IPR013780,IPR013785; PFAM:PF17801; SECRETED:SignalP(1-16); go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_10942A COG:S; EggNog:ENOG410PFA9; InterPro:IPR001810,IPR032675; PFAM:PF12937; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_10943S COG:S; EggNog:ENOG410PN30; InterPro:IPR011057,IPR006913; PFAM:PF04828; go_function: GO:0016846 - carbon-sulfur lyase activity [Evidence IEA] AKAW2_10944S COG:S; EggNog:ENOG410PP1Q; InterPro:IPR008701 AKAW2_10945S COG:S; EggNog:ENOG410PMX6; InterPro:IPR001602,IPR035917; PFAM:PF01894 AKAW2_10946A COG:C; EggNog:ENOG410PPT3; InterPro:IPR019401; PFAM:PF10276 AKAW2_10947S COG:S; EggNog:ENOG410PSM5 AKAW2_10949A BUSCO:EOG09264E6Z; COG:H; EggNog:ENOG410PI3Q; InterPro:IPR027417,IPR001977; PFAM:PF01121; TransMembrane:1 (o237-263i); go_function: GO:0004140 - dephospho-CoA kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0015937 - coenzyme A biosynthetic process [Evidence IEA] AKAW2_10950A COG:G; EggNog:ENOG410PG0X; InterPro:IPR005829,IPR005828,IPR003663,IPR036259, IPR020846; PFAM:PF00083,PF07690; TransMembrane:12 (i7-30o58-77i86-106o112-132i144-162o174-196i266-289o301- 323i335-354o366-390i402-425o431-451i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_10952S COG:S; EggNog:ENOG410PVDC; InterPro:IPR021858; PFAM:PF11951 AKAW2_10951A COG:S; EggNog:ENOG410PUGN; InterPro:IPR036864,IPR001138; PFAM:PF00172; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_10953A COG:T; EggNog:ENOG410PKMA; InterPro:IPR017946,IPR035892,IPR000909,IPR001192, IPR001711; PFAM:PF00388,PF00387; go_function: GO:0004435 - phosphatidylinositol phospholipase C activity [Evidence IEA]; go_function: GO:0008081 - phosphoric diester hydrolase activity [Evidence IEA]; go_process: GO:0006629 - lipid metabolic process [Evidence IEA]; go_process: GO:0007165 - signal transduction [Evidence IEA]; go_process: GO:0035556 - intracellular signal transduction [Evidence IEA] AKAW2_10954A BUSCO:EOG09265KQ4; COG:S; EggNog:ENOG410PR5G; InterPro:IPR013870; PFAM:PF08561 AKAW2_10955A COG:M; EggNog:ENOG410PM6B; InterPro:IPR016040,IPR036291,IPR005886; PFAM:PF16363,PF07993,PF01370; go_function: GO:0003978 - UDP-glucose 4-epimerase activity [Evidence IEA]; go_process: GO:0006012 - galactose metabolic process [Evidence IEA] AKAW2_10956S CAZy:GH135; COG:S; EggNog:ENOG410PRJ3; InterPro:IPR021986; PFAM:PF12138; TransMembrane:1 (i20-43o) AKAW2_10957A CAZy:GH114; COG:S; EggNog:ENOG410PJDR; InterPro:IPR017853,IPR004352,IPR013785; PFAM:PF03537; TransMembrane:1 (i26-51o); go_function: GO:0003824 - catalytic activity [Evidence IEA] AKAW2_10959A COG:S; EggNog:ENOG410PKR3; InterPro:IPR011330; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_10960S COG:M; EggNog:ENOG410PKT7; PFAM:PF00534,PF13692; TransMembrane:14 (o20-41i821-841o861-885i897-922o928-952i964-981o987- 1004i1147-1163o1183-1200i1244-1265o1271-1288i1300- 1317o1323-1345i1667-1684o) AKAW2_10961A COG:O; EggNog:ENOG410PGX8; InterPro:IPR001375,IPR038554,IPR029058,IPR002469; MEROPS:MER0000405; PFAM:PF00930,PF00326; TransMembrane:1 (i91-111o); go_function: GO:0008236 - serine-type peptidase activity [Evidence IEA]; go_process: GO:0006508 - proteolysis [Evidence IEA] AKAW2_10963S BUSCO:EOG09260DUR; COG:U; EggNog:ENOG410Q8MH; InterPro:IPR024554,IPR024555,IPR001683,IPR036871; PFAM:PF12825,PF12828,PF00787; go_function: GO:0035091 - phosphatidylinositol binding [Evidence IEA] AKAW2_10964S COG:S; EggNog:ENOG410PS0G; InterPro:IPR010666; PFAM:PF06839; go_function: GO:0008270 - zinc ion binding [Evidence IEA] AKAW2_10965S BUSCO:EOG09262I0R; COG:A; EggNog:ENOG410PI9Q; InterPro:IPR030382,IPR025792,IPR029063; PFAM:PF02475; go_function: GO:0009019 - tRNA (guanine-N1-)-methyltransferase activity [Evidence IEA]; go_process: GO:0030488 - tRNA methylation [Evidence IEA] AKAW2_10966S BUSCO:EOG09264ZI5; COG:K; EggNog:ENOG410PP7T; InterPro:IPR006590,IPR010997,IPR038324,IPR005574; PFAM:PF03874; go_component: GO:0030880 - RNA polymerase complex [Evidence IEA]; go_function: GO:0000166 - nucleotide binding [Evidence IEA]; go_process: GO:0006352 - DNA-templated transcription, initiation [Evidence IEA]; go_process: GO:0044237 - cellular metabolic process [Evidence IEA] AKAW2_10967S COG:K; EggNog:ENOG410PGMJ; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF04082; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_10968A COG:S; EggNog:ENOG410PWDQ; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; TransMembrane:2 (o445-467i661-680o); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_10969S COG:Q; EggNog:ENOG410PFEK; InterPro:IPR015889,IPR007535,IPR000627; PFAM:PF04444,PF00775; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0008199 - ferric iron binding [Evidence IEA]; go_function: GO:0016702 - oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [Evidence IEA]; go_function: GO:0018576 - catechol 1,2-dioxygenase activity [Evidence IEA]; go_process: GO:0006725 - cellular aromatic compound metabolic process [Evidence IEA]; go_process: GO:0009712 - catechol-containing compound metabolic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_10970S COG:E; EggNog:ENOG410PIV7; InterPro:IPR009770; PFAM:PF07063 AKAW2_10971S CAZy:AA3; COG:E; EggNog:ENOG410PH3P; InterPro:IPR012132,IPR036188,IPR000172,IPR007867; PFAM:PF05199,PF00732; SECRETED:SignalP(1-20); go_function: GO:0016614 - oxidoreductase activity, acting on CH-OH group of donors [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_10972A COG:J; EggNog:ENOG410PP2I; InterPro:IPR028909,IPR036164; PFAM:PF00829; go_component: GO:0005840 - ribosome [Evidence IEA] AKAW2_10973S BUSCO:EOG09263ZBF; COG:J; EggNog:ENOG410PJ4S; InterPro:IPR039411,IPR022309; PFAM:PF01201 AKAW2_10974A BUSCO:EOG092610LQ; COG:D; EggNog:ENOG410PHX5; InterPro:IPR017441,IPR008271,IPR027084,IPR000719, IPR011009; PFAM:PF07714,PF00069; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0004712 - protein serine/threonine/tyrosine kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA]; go_process: GO:0007093 - mitotic cell cycle checkpoint [Evidence IEA]; go_process: GO:0051304 - chromosome separation [Evidence IEA] AKAW2_10975S COG:S; EggNog:ENOG410Q2KH; SECRETED:SignalP(1-18) AKAW2_10976A COG:A; EggNog:ENOG410PNXE; InterPro:IPR002483,IPR036483; PFAM:PF01480; go_process: GO:0006397 - mRNA processing [Evidence IEA] AKAW2_10977S SECRETED:SignalP(1-16) AKAW2_10978A COG:S; EggNog:ENOG410Q167 AKAW2_10979S COG:Q; EggNog:ENOG410PGIV; InterPro:IPR011234,IPR036663; PFAM:PF01557; go_function: GO:0003824 - catalytic activity [Evidence IEA] AKAW2_10980A COG:S; EggNog:ENOG410Q03F AKAW2_10981A COG:J; EggNog:ENOG410PFHJ; InterPro:IPR027417,IPR001650,IPR014014,IPR014001, IPR011545,IPR000629; PFAM:PF04851,PF00270,PF00271; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0004386 - helicase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA] AKAW2_10982S COG:B,T; EggNog:ENOG410PGKP; InterPro:IPR001810,IPR041667,IPR036047,IPR003347; PFAM:PF00646,PF02373,PF12937; SECRETED:SignalP(1-19); go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_10983A COG:P; EggNog:ENOG410PPMQ; InterPro:IPR007274; PFAM:PF04145; TransMembrane:3 (o53-72i140-160o166-182i); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0005375 - copper ion transmembrane transporter activity [Evidence IEA]; go_process: GO:0035434 - copper ion transmembrane transport [Evidence IEA] AKAW2_10984S BUSCO:EOG092658WS; COG:K; EggNog:ENOG410PT7H; InterPro:IPR015418; PFAM:PF09340; go_component: GO:0000123 - histone acetyltransferase complex [Evidence IEA]; go_process: GO:0016573 - histone acetylation [Evidence IEA] AKAW2_10985A BUSCO:EOG092607QZ; COG:G; EggNog:ENOG410PH3N; InterPro:IPR028995,IPR015341,IPR037094,IPR000602, IPR027291,IPR011330,IPR011013,IPR041147,IPR011682; PFAM:PF17677,PF01074,PF09261,PF07748; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0004559 - alpha-mannosidase activity [Evidence IEA]; go_function: GO:0030246 - carbohydrate binding [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA]; go_process: GO:0006013 - mannose metabolic process [Evidence IEA] AKAW2_10986S BUSCO:EOG09265040; COG:S; EggNog:ENOG410PIMK; InterPro:IPR031838,IPR007785; PFAM:PF16803,PF05093; go_component: GO:0005737 - cytoplasm [Evidence IEA]; go_function: GO:0051536 - iron-sulfur cluster binding [Evidence IEA]; go_process: GO:0016226 - iron-sulfur cluster assembly [Evidence IEA] AKAW2_10987A COG:S; EggNog:ENOG410Q1TI AKAW2_10988A TransMembrane:1 (o79-97i) AKAW2_10990A COG:L; EggNog:ENOG410PKDX; InterPro:IPR015797,IPR000086; PFAM:PF00293; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_10991A COG:S; EggNog:ENOG410PGFS; InterPro:IPR011685,IPR033122; PFAM:PF07766; TransMembrane:1 (i208-228o); go_function: GO:0043022 - ribosome binding [Evidence IEA] AKAW2_10992A BUSCO:EOG09263JCT; COG:S; EggNog:ENOG410PHFB; InterPro:IPR021261; PFAM:PF10998; TransMembrane:8 (i167-184o190-207i214-236o242-261i273-292o324-345i386- 407o413-432i) AKAW2_10993A COG:S; EggNog:ENOG410PSMP; InterPro:IPR021264; PFAM:PF11001 AKAW2_10994A CAZy:GH79; COG:S; EggNog:ENOG410PJBK; InterPro:IPR017853,IPR031728; PFAM:PF16862; SECRETED:SignalP(1-21) AKAW2_10995A BUSCO:EOG092606CY; COG:D; EggNog:ENOG410PH43; InterPro:IPR010935,IPR003395,IPR027417,IPR036277, IPR028468,IPR024704; PFAM:PF06470,PF13555,PF02463; go_component: GO:0005694 - chromosome [Evidence IEA]; go_component: GO:0008278 - cohesin complex [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0007064 - mitotic sister chromatid cohesion [Evidence IEA]; go_process: GO:0051276 - chromosome organization [Evidence IEA] AKAW2_10996A COG:S; EggNog:ENOG410PU6K; TransMembrane:2 (i96-114o134-151i) AKAW2_10997S COG:C; EggNog:ENOG410PKBH; InterPro:IPR004167,IPR036625; PFAM:PF02817; go_function: GO:0016746 - transferase activity, transferring acyl groups [Evidence IEA] AKAW2_10998A COG:D; EggNog:ENOG410QD8S; InterPro:IPR036322,IPR015943,IPR019775,IPR001680, IPR033010,IPR017986; PFAM:PF00400; go_function: GO:0005515 - protein binding [Evidence IEA]; go_function: GO:0010997 - anaphase-promoting complex binding [Evidence IEA]; go_function: GO:0097027 - ubiquitin-protein transferase activator activity [Evidence IEA]; go_process: GO:1904668 - positive regulation of ubiquitin protein ligase activity [Evidence IEA] AKAW2_10999S COG:E; EggNog:ENOG410PGFT; InterPro:IPR001948,IPR023358; MEROPS:MER0003374; PFAM:PF02127; go_function: GO:0004177 - aminopeptidase activity [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006508 - proteolysis [Evidence IEA] AKAW2_11000S COG:S; EggNog:ENOG410PQJQ; InterPro:IPR013715,IPR038967; PFAM:PF08508; TransMembrane:3 (i58-83o103-121i154-173o); go_component: GO:0044695 - Dsc E3 ubiquitin ligase complex [Evidence IEA]; go_process: GO:0035103 - sterol regulatory element binding protein cleavage [Evidence IEA] AKAW2_11001A COG:O; EggNog:ENOG410PXHM; InterPro:IPR029045,IPR001907,IPR018215,IPR023562, IPR033135; MEROPS:MER0006046; PFAM:PF00574; go_function: GO:0004176 - ATP-dependent peptidase activity [Evidence IEA]; go_function: GO:0004252 - serine-type endopeptidase activity [Evidence IEA]; go_process: GO:0006508 - proteolysis [Evidence IEA] AKAW2_11002S COG:S; EggNog:ENOG410PXT1 AKAW2_11003A COG:P; EggNog:ENOG410PFJB; InterPro:IPR006349,IPR036412,IPR006357,IPR023214; PFAM:PF13242,PF13344,PF00702; go_function: GO:0016791 - phosphatase activity [Evidence IEA] AKAW2_11004A COG:L; EggNog:ENOG410PH5Y; InterPro:IPR003959,IPR027417,IPR003593,IPR013748, IPR008921; PFAM:PF13177,PF00004,PF08542; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA]; go_process: GO:0006260 - DNA replication [Evidence IEA] AKAW2_11005A COG:U; EggNog:ENOG410PMMI; InterPro:IPR005606; PFAM:PF03908; TransMembrane:2 (i227-245o257-277i); go_function: GO:0005484 - SNAP receptor activity [Evidence IEA]; go_process: GO:0006890 - retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [Evidence IEA] AKAW2_11006S COG:S; EggNog:ENOG410Q26N; InterPro:IPR019716; PFAM:PF10780 AKAW2_11007A COG:C; EggNog:ENOG410PFM5; InterPro:IPR008162,IPR036649; PFAM:PF00719; go_component: GO:0005737 - cytoplasm [Evidence IEA]; go_function: GO:0000287 - magnesium ion binding [Evidence IEA]; go_function: GO:0004427 - inorganic diphosphatase activity [Evidence IEA]; go_process: GO:0006796 - phosphate-containing compound metabolic process [Evidence IEA] AKAW2_11008S BUSCO:EOG092628FW; COG:J; EggNog:ENOG410PH64; InterPro:IPR001269,IPR018517,IPR035587,IPR013785; PFAM:PF01207; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0017150 - tRNA dihydrouridine synthase activity [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_process: GO:0008033 - tRNA processing [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_11009A COG:B; EggNog:ENOG410PG2X; InterPro:IPR038718,IPR000330,IPR027417,IPR014001, IPR001650; PFAM:PF00176,PF00271,PF04851; go_function: GO:0005524 - ATP binding [Evidence IEA] AKAW2_11010S COG:U; EggNog:ENOG410PS81; InterPro:IPR019013; PFAM:PF09446; TransMembrane:2 (i42-59o71-90i); go_process: GO:0070072 - vacuolar proton-transporting V-type ATPase complex assembly [Evidence IEA] AKAW2_11011A COG:S; EggNog:ENOG410PNSC; InterPro:IPR000644 AKAW2_11012S COG:C; EggNog:ENOG410PFFI; InterPro:IPR018108,IPR023395; PFAM:PF00153 AKAW2_11013S COG:S; EggNog:ENOG410PS0S; InterPro:IPR022024; PFAM:PF12223 AKAW2_11014A COG:S; EggNog:ENOG410PQFF; InterPro:IPR018809; PFAM:PF10295 AKAW2_11015A COG:J; EggNog:ENOG410PPN6; InterPro:IPR001780,IPR038661,IPR018266,IPR009000; PFAM:PF01247; go_component: GO:0005840 - ribosome [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_process: GO:0006412 - translation [Evidence IEA] AKAW2_11016S BUSCO:EOG09261N64; COG:G; EggNog:ENOG410PHEK; InterPro:IPR019796,IPR022675,IPR022674,IPR001282, IPR036291; PFAM:PF00479,PF02781; go_function: GO:0004345 - glucose-6-phosphate dehydrogenase activity [Evidence IEA]; go_function: GO:0016614 - oxidoreductase activity, acting on CH-OH group of donors [Evidence IEA]; go_function: GO:0050661 - NADP binding [Evidence IEA]; go_process: GO:0006006 - glucose metabolic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_11017S COG:G; EggNog:ENOG410PKCY; InterPro:IPR036259; PFAM:PF13347; TransMembrane:12 (i20-38o58-79i91-109o129-154i175-198o204-224i261-279o313- 333i369-386o392-413i491-515o544-563i) AKAW2_11018A COG:S; EggNog:ENOG410PGC4; InterPro:IPR037508,IPR012965; PFAM:PF08101 AKAW2_11019S COG:K; EggNog:ENOG410QEEN; InterPro:IPR033896,IPR036879,IPR002100; PFAM:PF00319; TransMembrane:1 (i32-50o); go_function: GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0046983 - protein dimerization activity [Evidence IEA]; go_process: GO:0045944 - positive regulation of transcription by RNA polymerase II [Evidence IEA] AKAW2_11020A COG:G; EggNog:ENOG410PKJQ; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:14 (i98-124o136-155i167-186o192-213i225-246o252-275i296- 315o321-341i362-383o395-419i428-450o456-477i489-512o570- 591i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_11021A COG:T; EggNog:ENOG410PI12; InterPro:IPR011992,IPR002048,IPR018247; PFAM:PF00036,PF13499,PF13405,PF13202,PF13833; go_function: GO:0005509 - calcium ion binding [Evidence IEA] AKAW2_11022A COG:Q; EggNog:ENOG410PVJM; InterPro:IPR036291,IPR002347; PFAM:PF08659,PF00106,PF13561; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_11023S COG:P; EggNog:ENOG410PN6U; InterPro:IPR036568,IPR013024,IPR006840; PFAM:PF04752; go_function: GO:0003839 - gamma-glutamylcyclotransferase activity [Evidence IEA]; go_process: GO:0006751 - glutathione catabolic process [Evidence IEA] AKAW2_11024A COG:A; EggNog:ENOG410PQQ1; InterPro:IPR000504,IPR012677,IPR035979; PFAM:PF00076; go_function: GO:0003676 - nucleic acid binding [Evidence IEA] AKAW2_11025S COG:S; EggNog:ENOG410PZ3U AKAW2_11027A COG:S; EggNog:ENOG410PS2H; InterPro:IPR037652; PFAM:PF19117; go_process: GO:0045040 - protein insertion into mitochondrial outer membrane [Evidence IEA]; go_process: GO:0070096 - mitochondrial outer membrane translocase complex assembly [Evidence IEA] AKAW2_11028S BUSCO:EOG09264OQ8; COG:J; EggNog:ENOG410PG7A; InterPro:IPR002735,IPR000048,IPR016190,IPR016189; PFAM:PF01873; go_function: GO:0003743 - translation initiation factor activity [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0006413 - translational initiation [Evidence IEA] AKAW2_11029A COG:S; EggNog:ENOG410PKQ4; InterPro:IPR016031,IPR002838,IPR036983; PFAM:PF01987 AKAW2_11030A COG:M; EggNog:ENOG410PMUV; InterPro:IPR002110,IPR036770,IPR020683; PFAM:PF12796,PF13637,PF13857; SECRETED:SignalP(1-19); TransMembrane:5 (n3-14c19/20o59-80i196-222o234-259i326-344o350-370i); go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_11031A COG:T; EggNog:ENOG410PPWP; InterPro:IPR001452,IPR036028; PFAM:PF07653,PF00018,PF14604; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_11032A COG:S; EggNog:ENOG410Q291 AKAW2_11033S BUSCO:EOG09264MN3; COG:K; EggNog:ENOG410PN0T; InterPro:IPR013729,IPR010982,IPR001387; PFAM:PF08523,PF01381; go_function: GO:0003677 - DNA binding [Evidence IEA] AKAW2_11034A BUSCO:EOG09262W7C; COG:J; EggNog:ENOG410PH6Q; InterPro:IPR027525,IPR036322,IPR015943,IPR019775, IPR001680,IPR017986; PFAM:PF00400; go_component: GO:0005737 - cytoplasm [Evidence IEA]; go_component: GO:0005852 - eukaryotic translation initiation factor 3 complex [Evidence IEA]; go_function: GO:0003743 - translation initiation factor activity [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_11035S COG:H; EggNog:ENOG410PFGE; InterPro:IPR020628,IPR020867,IPR020631,IPR000672, IPR027417,IPR036291,IPR000559,IPR020630; PFAM:PF02882,PF01268,PF00763; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0004329 - formate-tetrahydrofolate ligase activity [Evidence IEA]; go_function: GO:0004488 - methylenetetrahydrofolate dehydrogenase (NADP+) activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_11036S COG:C; EggNog:ENOG410PFHR; InterPro:IPR019818,IPR024084,IPR004790; PFAM:PF00180; go_function: GO:0000287 - magnesium ion binding [Evidence IEA]; go_function: GO:0004450 - isocitrate dehydrogenase (NADP+) activity [Evidence IEA]; go_function: GO:0016616 - oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Evidence IEA]; go_function: GO:0051287 - NAD binding [Evidence IEA]; go_process: GO:0006102 - isocitrate metabolic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_11037S COG:S; EggNog:ENOG410PKP8; TransMembrane:6 (o6-24i36-55o79-102i114-143o163-181i193-212o) AKAW2_11038A COG:S; EggNog:ENOG410PZ6K AKAW2_11039A CAZy:GH28; COG:G; EggNog:ENOG410PJR1; InterPro:IPR000743,IPR012334,IPR011050; PFAM:PF00295; SECRETED:SignalP(1-19); go_function: GO:0004650 - polygalacturonase activity [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_11040S COG:S; EggNog:ENOG410PT6J; InterPro:IPR023393 AKAW2_11041S COG:T; EggNog:ENOG410PUX0; InterPro:IPR000719,IPR011009,IPR008271; PFAM:PF07714,PF00069; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_11042A COG:S; EggNog:ENOG410PK5F; InterPro:IPR001737,IPR029063 AKAW2_11043S COG:T; EggNog:ENOG410PIV2; InterPro:IPR000555,IPR037518,IPR015063,IPR044098; MEROPS:MER0029722; PFAM:PF08969,PF01398; go_function: GO:0005515 - protein binding [Evidence IEA]; go_function: GO:0008237 - metallopeptidase activity [Evidence IEA]; go_function: GO:0061578 - Lys63-specific deubiquitinase activity [Evidence IEA]; go_function: GO:0070122 - isopeptidase activity [Evidence IEA]; go_process: GO:0016579 - protein deubiquitination [Evidence IEA]; go_process: GO:0070536 - protein K63-linked deubiquitination [Evidence IEA] AKAW2_11044S COG:S; EggNog:ENOG410PXQS; InterPro:IPR000073,IPR029058; PFAM:PF12697 AKAW2_11045S BUSCO:EOG092645TJ; COG:K; EggNog:ENOG410PFX1; InterPro:IPR035100,IPR003617,IPR036575,IPR017923, IPR035441,IPR003618,IPR001222,IPR006289; PFAM:PF01096,PF08711,PF07500; go_component: GO:0005634 - nucleus [Evidence IEA]; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_11046S COG:S; EggNog:ENOG410PQW1 AKAW2_11047A CAZy:CE8; COG:G; EggNog:ENOG410PI3K; InterPro:IPR012334,IPR011050,IPR000070; PFAM:PF01095; SECRETED:SignalP(1-18); go_function: GO:0030599 - pectinesterase activity [Evidence IEA]; go_process: GO:0042545 - cell wall modification [Evidence IEA] AKAW2_11048A COG:P; EggNog:ENOG410PFW2; InterPro:IPR018303,IPR023298,IPR023299,IPR001757, IPR036412,IPR006534,IPR008250; PFAM:PF00122,PF00702; TransMembrane:9 (o33-52i224-245o265-292i623-644o650-672i684-704o724- 740i752-772o801-825i); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0000166 - nucleotide binding [Evidence IEA]; go_function: GO:0008553 - proton-exporting ATPase activity, phosphorylative mechanism [Evidence IEA]; go_process: GO:0120029 - proton export across plasma membrane [Evidence IEA] AKAW2_11050A COG:S; EggNog:ENOG410PPDZ; InterPro:IPR041712,IPR001279,IPR036866 AKAW2_11051A BUSCO:EOG09260KNI; COG:A,T,Y; EggNog:ENOG410PGV5; InterPro:IPR001611,IPR032675; PFAM:PF13516; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_11052S COG:O; EggNog:ENOG410PSUK; InterPro:IPR009069,IPR007745; PFAM:PF05051; go_component: GO:0005758 - mitochondrial intermembrane space [Evidence IEA]; go_function: GO:0005507 - copper ion binding [Evidence IEA]; go_function: GO:0016531 - copper chaperone activity [Evidence IEA] AKAW2_11053A BUSCO:EOG09260NZ8; CAZy:GT57; COG:G; EggNog:ENOG410PGJR; InterPro:IPR039488,IPR004856; TransMembrane:13 (o55-77i157-179o191-209i221-247o253-271i278-303o377- 398i405-423o429-446i453-470o476-499i520-542o548-570i); go_component: GO:0005783 - endoplasmic reticulum [Evidence IEA]; go_function: GO:0016758 - transferase activity, transferring hexosyl groups [Evidence IEA]; go_function: GO:0042281 - dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity [Evidence IEA]; go_process: GO:0006488 - dolichol-linked oligosaccharide biosynthetic process [Evidence IEA] AKAW2_11054S COG:K; EggNog:ENOG410QDZZ; InterPro:IPR000504,IPR035979,IPR012677,IPR034276, IPR034272; PFAM:PF00076; go_function: GO:0003676 - nucleic acid binding [Evidence IEA] AKAW2_11055S COG:S; EggNog:ENOG410PPJP; TransMembrane:1 (o340-364i) AKAW2_11056A BUSCO:EOG09261XNJ; COG:O; EggNog:ENOG410PFPI; InterPro:IPR002423,IPR027410,IPR027413,IPR017998, IPR002194,IPR012717,IPR027409; PFAM:PF00118; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0051082 - unfolded protein binding [Evidence IEA]; go_process: GO:0006457 - protein folding [Evidence IEA] AKAW2_11057S COG:O; EggNog:ENOG410PG2P; InterPro:IPR003959,IPR003960,IPR027417,IPR003593, IPR035245,IPR005937; PFAM:PF00004; go_component: GO:0005737 - cytoplasm [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016787 - hydrolase activity [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA]; go_function: GO:0036402 - proteasome-activating ATPase activity [Evidence IEA]; go_process: GO:0030163 - protein catabolic process [Evidence IEA] AKAW2_11058S COG:C; EggNog:ENOG410PFY0; InterPro:IPR036188,IPR037099,IPR003953,IPR003952, IPR027477,IPR014006,IPR011281,IPR015939; PFAM:PF02910,PF00890; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0016627 - oxidoreductase activity, acting on the CH-CH group of donors [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_process: GO:0006099 - tricarboxylic acid cycle [Evidence IEA]; go_process: GO:0022900 - electron transport chain [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_11059S COG:S; EggNog:ENOG410PTYI; TransMembrane:1 (o170-194i) AKAW2_11060A COG:S; EggNog:ENOG410PS2Z; InterPro:IPR013653,IPR016181; PFAM:PF08445; go_function: GO:0016747 - transferase activity, transferring acyl groups other than amino-acyl groups [Evidence IEA] AKAW2_11061A COG:S; EggNog:ENOG410Q1PA AKAW2_11062S COG:S; EggNog:ENOG410Q1WM AKAW2_11063S COG:O; EggNog:ENOG410Q2F5; TransMembrane:2 (i30-50o95-114i) AKAW2_11064A COG:S; EggNog:ENOG410PVHM; InterPro:IPR008949 AKAW2_11065S COG:S; EggNog:ENOG410PG2S; InterPro:IPR011009,IPR004147; PFAM:PF03109; TransMembrane:2 (i75-94o607-626i) AKAW2_11066A COG:Q; EggNog:ENOG410PMQ6; InterPro:IPR001128,IPR002403,IPR017972,IPR036396; TransMembrane:1 (o20-40i); go_function: GO:0004497 - monooxygenase activity [Evidence IEA]; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_11067S COG:S; EggNog:ENOG410PQ8R; TransMembrane:6 (o24-44i56-83o103-126i138-160o180-199i220-237o) AKAW2_11068A COG:G; EggNog:ENOG410PH3B; InterPro:IPR011701,IPR036259; PFAM:PF07690; TransMembrane:6 (i30-52o58-77i98-118o138-156i163-182o307-326i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_11069A COG:G; EggNog:ENOG410PH3B; InterPro:IPR020846,IPR011701,IPR036259; SECRETED:SignalP(1-30); TransMembrane:4 (n14-25c30/31o54-72i84-109o115-134i141-163o); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_11070S COG:S; EggNog:ENOG410PKXT; InterPro:IPR012312; PFAM:PF01814 AKAW2_11071S COG:Q; EggNog:ENOG410PGTM; InterPro:IPR001128,IPR002401,IPR036396; PFAM:PF00067; TransMembrane:1 (o16-34i); go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_11072S COG:S; EggNog:ENOG410PX4E; InterPro:IPR010730; PFAM:PF06985 AKAW2_11073A COG:S; EggNog:ENOG410PSXD AKAW2_11074S BUSCO:EOG09263J3H; COG:U; EggNog:ENOG410PGDE; InterPro:IPR021538,IPR000727,IPR010989; PFAM:PF11416,PF05739; TransMembrane:1 (i322-341o); go_component: GO:0016020 - membrane [Evidence IEA]; go_process: GO:0016192 - vesicle-mediated transport [Evidence IEA] AKAW2_11075A COG:G,M; EggNog:ENOG410Q8ND; InterPro:IPR036291,IPR008030; PFAM:PF13460,PF05368 AKAW2_11076S COG:V; EggNog:ENOG410PN7G; InterPro:IPR036291,IPR001509; PFAM:PF13460,PF01073,PF01370; go_function: GO:0003824 - catalytic activity [Evidence IEA] AKAW2_11077S COG:S; EggNog:ENOG410PPNV; InterPro:IPR036922,IPR017941; PFAM:PF13806,PF00355; go_function: GO:0051537 - 2 iron, 2 sulfur cluster binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_11078A COG:G; EggNog:ENOG410PVPW; InterPro:IPR011701,IPR036259; PFAM:PF07690; TransMembrane:7 (o21-41i105-123o135-155i176-195o201-223i235-257o269-290i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_11079A COG:G; EggNog:ENOG410PVPW; InterPro:IPR020846,IPR011701,IPR036259; TransMembrane:4 (i44-65o85-104i116-134o140-158i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_11080A InterPro:IPR004827; go_function: GO:0003700 - DNA-binding transcription factor activity [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_11081A COG:Q; EggNog:ENOG410PXEZ; InterPro:IPR042099,IPR000873,IPR020845 AKAW2_11082S COG:E; EggNog:ENOG410PGQW; InterPro:IPR023603,IPR001597,IPR015424,IPR015421, IPR015422; PFAM:PF01212; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0016829 - lyase activity [Evidence IEA]; go_process: GO:0006520 - cellular amino acid metabolic process [Evidence IEA] AKAW2_11083S COG:K; EggNog:ENOG410PP1W; InterPro:IPR007219; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA] AKAW2_11085S COG:S; EggNog:ENOG410PNEP AKAW2_11086A COG:S; EggNog:ENOG410PJFD; PFAM:PF13398; TransMembrane:6 (i29-48o106-124i131-147o153-171i178-195o225-246i) AKAW2_11087A COG:S; EggNog:ENOG410PV62; InterPro:IPR010699; PFAM:PF06912; TransMembrane:6 (i95-118o144-167i179-197o217-239i273-293o299-316i) AKAW2_11088A COG:U; EggNog:ENOG410PII9; InterPro:IPR009571; TransMembrane:3 (n9-22c26/27o83-106i118-144o150-172i); go_component: GO:0005886 - plasma membrane [Evidence IEA] AKAW2_11089A COG:L; EggNog:ENOG410PUXI; InterPro:IPR010730; PFAM:PF06985 AKAW2_11090A COG:P,Q; EggNog:ENOG410PHKD; InterPro:IPR017938,IPR017927,IPR013130,IPR013121, IPR039261,IPR013112; PFAM:PF08022,PF01794,PF08030; TransMembrane:7 (o51-70i122-141o161-178i199-219o239-256i263-282o294-312i); go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_11092S CAZy:GH55; COG:S; EggNog:ENOG410PIPD; InterPro:IPR012334,IPR011050,IPR024535; PFAM:PF12708; SECRETED:SignalP(1-22) AKAW2_11093S COG:S; EggNog:ENOG410PIWI; InterPro:IPR021840; PFAM:PF11915; TransMembrane:8 (i253-276o296-319i361-386o406-425i558-579o599-622i674- 700o706-733i) AKAW2_11094S COG:S; EggNog:ENOG410PM0B; InterPro:IPR036864,IPR021858,IPR001138; PFAM:PF00172,PF11951; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_11096S COG:S; EggNog:ENOG410PYW1; InterPro:IPR038814; TransMembrane:1 (n2-10c18/19o56-73i) AKAW2_11095A COG:S; EggNog:ENOG410PGDM; InterPro:IPR000467,IPR000504,IPR036443,IPR035979, IPR012677,IPR013087,IPR001876; PFAM:PF01585,PF00641,PF00076; go_function: GO:0003676 - nucleic acid binding [Evidence IEA] AKAW2_11097S COG:I; EggNog:ENOG410PFXA; InterPro:IPR016035,IPR002642; PFAM:PF01735; go_function: GO:0004620 - phospholipase activity [Evidence IEA]; go_process: GO:0009395 - phospholipid catabolic process [Evidence IEA] AKAW2_11099A COG:S; EggNog:ENOG410Q27W; SECRETED:SignalP(1-19) AKAW2_11100A CAZy:GH13; COG:G; EggNog:ENOG410PGUZ; InterPro:IPR017853,IPR006047,IPR013780; PFAM:PF00128; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_11101A COG:G; EggNog:ENOG410Q1FG; InterPro:IPR023271,IPR000425; PFAM:PF00230; TransMembrane:5 (n19-29c34/35o44-63i95-113o157-177i189-210o236-256i); go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0015267 - channel activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_11102A InterPro:IPR032710 AKAW2_11103S COG:Q; EggNog:ENOG410PUAV; InterPro:IPR001128,IPR017972,IPR002401,IPR036396; PFAM:PF00067; TransMembrane:1 (i50-72o); go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_11104A COG:S; EggNog:ENOG410PJQR; InterPro:IPR017945,IPR006070; PFAM:PF01300; go_function: GO:0003725 - double-stranded RNA binding [Evidence IEA] AKAW2_11105S COG:S; EggNog:ENOG410QDYX; InterPro:IPR036864,IPR021858,IPR001138; PFAM:PF00172,PF11951; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_11106S COG:S; EggNog:ENOG410PKCG; InterPro:IPR043750; PFAM:PF18951; SECRETED:SignalP(1-17) AKAW2_11107S COG:S; EggNog:ENOG410Q2UF; InterPro:IPR014710,IPR011051 AKAW2_11108A COG:S; EggNog:ENOG410PKRE; InterPro:IPR010839; PFAM:PF07287 AKAW2_11110S COG:I; EggNog:ENOG410PV78 AKAW2_11111S COG:I; EggNog:ENOG410PV78; InterPro:IPR023606,IPR003673; PFAM:PF02515; go_function: GO:0008410 - CoA-transferase activity [Evidence IEA] AKAW2_11109A COG:K; EggNog:ENOG410PGYQ; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_11112A COG:I; EggNog:ENOG410PHHA; InterPro:IPR019819,IPR019826,IPR002018,IPR029058; MEROPS:MER0030934; PFAM:PF00135; SECRETED:SignalP(1-16) AKAW2_11113S COG:H; EggNog:ENOG410PMW6; InterPro:IPR036563,IPR028888,IPR003448; PFAM:PF02391; go_component: GO:0005829 - cytosol [Evidence IEA]; go_component: GO:0019008 - molybdopterin synthase complex [Evidence IEA]; go_function: GO:0030366 - molybdopterin synthase activity [Evidence IEA]; go_process: GO:0006777 - Mo-molybdopterin cofactor biosynthetic process [Evidence IEA] AKAW2_11114A BUSCO:EOG09264ENO; COG:C; EggNog:ENOG410PG4G; InterPro:IPR036249,IPR017276,IPR003782,IPR013766; PFAM:PF02630,PF00578; TransMembrane:1 (o89-110i); go_component: GO:0005743 - mitochondrial inner membrane [Evidence IEA]; go_function: GO:0005507 - copper ion binding [Evidence IEA]; go_function: GO:0016531 - copper chaperone activity [Evidence IEA]; go_process: GO:0006878 - cellular copper ion homeostasis [Evidence IEA]; go_process: GO:0008535 - respiratory chain complex IV assembly [Evidence IEA] AKAW2_11115A COG:S; EggNog:ENOG410PJKH AKAW2_11116S COG:S; EggNog:ENOG410Q4K6 AKAW2_11117A COG:S; EggNog:ENOG410PR4G; InterPro:IPR038881,IPR019191; PFAM:PF09811 AKAW2_11118S COG:M; EggNog:ENOG410Q2HB AKAW2_11119A COG:S; EggNog:ENOG410Q1WK; SECRETED:SignalP(1-22) AKAW2_11120A BUSCO:EOG092624UF; COG:P; EggNog:ENOG410PH6F; InterPro:IPR004752,IPR024371,IPR036259; TransMembrane:12 (i91-113o119-137i158-178o198-221i233-252o272-295i316- 337o357-376i388-412o418-445i457-477o535-554i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0008521 - acetyl-CoA transmembrane transporter activity [Evidence IEA] AKAW2_11121S COG:S; EggNog:ENOG410PNBY; InterPro:IPR018464; PFAM:PF09496; go_component: GO:0000776 - kinetochore [Evidence IEA]; go_process: GO:0034508 - centromere complex assembly [Evidence IEA] AKAW2_11122A COG:S; EggNog:ENOG410PXPK AKAW2_11123A CAZy:CE10; COG:V; EggNog:ENOG410PWZP; InterPro:IPR029058,IPR013094; MEROPS:MER0034665; PFAM:PF00326,PF07859; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_11124A CAZy:GT69; COG:S; EggNog:ENOG410PKUE; InterPro:IPR021047; PFAM:PF11735; TransMembrane:1 (i72-94o) AKAW2_11128A COG:P; EggNog:ENOG410PG6R; InterPro:IPR001248,IPR030175,IPR026030,IPR038271; PFAM:PF02133; TransMembrane:12 (i213-234o240-262i283-302o322-343i350-369o389-411i423- 443o477-501i513-531o543-564i585-607o622-641i); go_component: GO:0005886 - plasma membrane [Evidence IEA]; go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_function: GO:0031924 - vitamin B6 transmembrane transporter activity [Evidence IEA]; go_process: GO:0031919 - vitamin B6 transport [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_11129S COG:S; EggNog:ENOG410PMVQ; TransMembrane:7 (o17-35i47-67o104-124i136-155o175-202i214-234o254-275i) AKAW2_11130A COG:S; EggNog:ENOG410PND5; InterPro:IPR039362,IPR039113,IPR040666; PFAM:PF18388; go_process: GO:0000045 - autophagosome assembly [Evidence IEA] AKAW2_11131S COG:C; EggNog:ENOG410PJ9A; InterPro:IPR023210,IPR036812; PFAM:PF00248 AKAW2_11132S COG:U; EggNog:ENOG410PH2C; InterPro:IPR022812,IPR027417,IPR001401,IPR000375, IPR030381; PFAM:PF00350,PF01031; go_function: GO:0003924 - GTPase activity [Evidence IEA]; go_function: GO:0005525 - GTP binding [Evidence IEA] AKAW2_11133S BUSCO:EOG09263YFX; COG:H; EggNog:ENOG410PGAA; InterPro:IPR035929,IPR007085; TransMembrane:2 (i164-184o190-207i) AKAW2_11134S COG:S; EggNog:ENOG410QEGN; InterPro:IPR003378; go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0016757 - transferase activity, transferring glycosyl groups [Evidence IEA] AKAW2_11135A CAZy:CE4; COG:H; EggNog:ENOG410PK45; InterPro:IPR002509,IPR011330; PFAM:PF01522; SECRETED:SignalP(1-19); go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0016810 - hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_11136A COG:A; EggNog:ENOG410PFY4; InterPro:IPR027417,IPR001650; PFAM:PF00271 AKAW2_11137A COG:A; EggNog:ENOG410PFY4; InterPro:IPR027417,IPR014014,IPR014001,IPR011545, IPR000629; PFAM:PF00270; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0004386 - helicase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA] AKAW2_11138S BUSCO:EOG09262IP2; COG:H; EggNog:ENOG410PFR3; InterPro:IPR004567,IPR043129; PFAM:PF03630; go_function: GO:0004594 - pantothenate kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0015937 - coenzyme A biosynthetic process [Evidence IEA] AKAW2_11139S COG:S; EggNog:ENOG410Q2NY AKAW2_11140S COG:I; EggNog:ENOG410PH39; InterPro:IPR009450; PFAM:PF06432; TransMembrane:8 (i184-212o218-236i356-375o387-405i417-435o441-458i470- 489o495-519i); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0017176 - phosphatidylinositol N-acetylglucosaminyltransferase activity [Evidence IEA]; go_process: GO:0006506 - GPI anchor biosynthetic process [Evidence IEA] AKAW2_11141S CAZy:GH18; COG:G; EggNog:ENOG410PI4X; InterPro:IPR036861,IPR011583,IPR001223,IPR017853, IPR001002,IPR001579,IPR018371; PFAM:PF00187,PF00704; SECRETED:SignalP(1-16); go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_function: GO:0008061 - chitin binding [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_11142A COG:T; EggNog:ENOG410QDWC; InterPro:IPR001789,IPR003594,IPR003661,IPR036890, IPR036097,IPR011006,IPR004358,IPR029016,IPR005467; PFAM:PF00512,PF02518,PF00072; go_function: GO:0000155 - phosphorelay sensor kinase activity [Evidence IEA]; go_function: GO:0016772 - transferase activity, transferring phosphorus-containing groups [Evidence IEA]; go_process: GO:0000160 - phosphorelay signal transduction system [Evidence IEA]; go_process: GO:0007165 - signal transduction [Evidence IEA]; go_process: GO:0016310 - phosphorylation [Evidence IEA] AKAW2_11143A COG:G; EggNog:ENOG410PH2S; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i144-167o187-206i211-228o240-263i270-293o299-319i510- 534o554-578i599-620o626-652i672-688o694-716i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_11144S COG:S; EggNog:ENOG410PM05; InterPro:IPR036259; TransMembrane:12 (i22-48o68-90i97-129o149-166i187-210o216-236i257-276o282- 299i320-340o346-365i377-403o415-436i) AKAW2_11145S COG:S; EggNog:ENOG410Q0X1; InterPro:IPR013783,IPR036452,IPR011483; PFAM:PF07632; SECRETED:SignalP(1-17) AKAW2_11146S COG:S; EggNog:ENOG410PPWM; InterPro:IPR008972; SECRETED:SignalP(1-24); TransMembrane:1 (n7-18c24/25o218-240i) AKAW2_11147A COG:S; EggNog:ENOG410PQ78; SECRETED:SignalP(1-18) AKAW2_11148A COG:S; EggNog:ENOG410Q2SV AKAW2_11149S BUSCO:EOG092646CB; COG:S; EggNog:ENOG410PJC6; InterPro:IPR001727; PFAM:PF01169; SECRETED:SignalP(1-19); TransMembrane:6 (n8-16c21/22o249-272i279-299o311-328i421-440o460-481i493- 511o) AKAW2_11150S COG:S; EggNog:ENOG410PTXW; InterPro:IPR001005,IPR009057,IPR017930; PFAM:PF00249 AKAW2_11151A SECRETED:SignalP(1-17) AKAW2_11152S COG:S; EggNog:ENOG410PMYC; InterPro:IPR036864,IPR001138; PFAM:PF00172; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_11154A COG:G,O; EggNog:ENOG410PPVN; InterPro:IPR002889; PFAM:PF01822; SECRETED:SignalP(1-23) AKAW2_11155S COG:E; EggNog:ENOG410PHSC; InterPro:IPR001261,IPR017141,IPR002933,IPR011650, IPR036264; MEROPS:MER0001269; PFAM:PF01546,PF07687; SECRETED:SignalP(1-24); go_function: GO:0004181 - metallocarboxypeptidase activity [Evidence IEA]; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_11156A COG:S; EggNog:ENOG410PHIS; InterPro:IPR033433,IPR032514,IPR014870; PFAM:PF17168,PF16335,PF08760; SECRETED:SignalP(1-19) AKAW2_11157A COG:S; EggNog:ENOG410Q2VP; InterPro:IPR039535,IPR011047; PFAM:PF05935,PF14269; SECRETED:SignalP(1-16); TransMembrane:1 (n3-11c16/17o566-587i) AKAW2_11158A COG:S; EggNog:ENOG410PG1M; InterPro:IPR037104,IPR018502; PFAM:PF00191; go_function: GO:0005509 - calcium ion binding [Evidence IEA]; go_function: GO:0005544 - calcium-dependent phospholipid binding [Evidence IEA] AKAW2_11160A COG:S; EggNog:ENOG410PIU7; InterPro:IPR030379,IPR027417; go_function: GO:0005525 - GTP binding [Evidence IEA] AKAW2_11161A COG:S; EggNog:ENOG410PIDW; InterPro:IPR009291; SECRETED:SignalP(1-20) AKAW2_11162A COG:Q; EggNog:ENOG410PND2; InterPro:IPR023389,IPR014980; PFAM:PF08883 AKAW2_11163A COG:S; EggNog:ENOG410PPHP AKAW2_11164S COG:S; EggNog:ENOG410PMYM; InterPro:IPR037475; go_component: GO:0031617 - NMS complex [Evidence IEA]; go_process: GO:0034501 - protein localization to kinetochore [Evidence IEA] AKAW2_11165A COG:J; EggNog:ENOG410PG10; InterPro:IPR036986,IPR022801,IPR001912,IPR002942, IPR018079,IPR005710; PFAM:PF00163,PF01479; go_component: GO:0015935 - small ribosomal subunit [Evidence IEA]; go_function: GO:0003723 - RNA binding [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_function: GO:0019843 - rRNA binding [Evidence IEA]; go_process: GO:0006412 - translation [Evidence IEA] AKAW2_11166S COG:J; EggNog:ENOG410PHM8; InterPro:IPR036948,IPR018259,IPR008991,IPR001147; PFAM:PF01157; go_component: GO:0005840 - ribosome [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_process: GO:0006412 - translation [Evidence IEA] AKAW2_11167S COG:S; EggNog:ENOG410PJ57 AKAW2_11169A COG:B; EggNog:ENOG410PHAU; InterPro:IPR000953,IPR036388,IPR016197,IPR025995, IPR016181,IPR040706,IPR002717; PFAM:PF01853,PF11717,PF17772; go_function: GO:0004402 - histone acetyltransferase activity [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA]; go_process: GO:0016573 - histone acetylation [Evidence IEA] AKAW2_11170A BUSCO:EOG09261CXQ; COG:A,D; EggNog:ENOG410PFBZ; InterPro:IPR017930,IPR009057,IPR021786,IPR001005; PFAM:PF00249,PF13921,PF11831 AKAW2_11171S BUSCO:EOG09263C55; COG:L; EggNog:ENOG410PKBP; InterPro:IPR011687; PFAM:PF07767 AKAW2_11172S BUSCO:EOG092646PE; COG:L; EggNog:ENOG410PK7W; InterPro:IPR012337,IPR036397,IPR013520,IPR037431; PFAM:PF00929; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0008408 - 3'-5' exonuclease activity [Evidence IEA]; go_process: GO:0006364 - rRNA processing [Evidence IEA] AKAW2_11173S COG:S; EggNog:ENOG410PR3W; InterPro:IPR013924; PFAM:PF08615; go_component: GO:0032299 - ribonuclease H2 complex [Evidence IEA]; go_process: GO:0006401 - RNA catabolic process [Evidence IEA] AKAW2_11174S COG:O; EggNog:ENOG410PFAX; InterPro:IPR011145,IPR036265,IPR008594; PFAM:PF05652,PF11969; go_function: GO:0016787 - hydrolase activity [Evidence IEA]; go_process: GO:0000290 - deadenylation-dependent decapping of nuclear-transcribed mRNA [Evidence IEA] AKAW2_11176S COG:O; EggNog:ENOG410PFAX; InterPro:IPR038765,IPR036959,IPR001578; MEROPS:MER0000836; PFAM:PF01088; go_function: GO:0004843 - thiol-dependent ubiquitin-specific protease activity [Evidence IEA]; go_process: GO:0006511 - ubiquitin-dependent protein catabolic process [Evidence IEA] AKAW2_11175A COG:K,T; EggNog:ENOG410PQ9D; InterPro:IPR002052,IPR007757; PFAM:PF05063; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0008168 - methyltransferase activity [Evidence IEA]; go_process: GO:0032259 - methylation [Evidence IEA] AKAW2_11177A COG:A; EggNog:ENOG410PFWH; InterPro:IPR001313,IPR000504,IPR011989,IPR016024, IPR012677,IPR033133,IPR035979; PFAM:PF00806,PF00076; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0003723 - RNA binding [Evidence IEA] AKAW2_11178S COG:S; EggNog:ENOG410PM2F; InterPro:IPR013272,IPR008895; PFAM:PF05764,PF08265; go_component: GO:0005634 - nucleus [Evidence IEA]; go_process: GO:0006338 - chromatin remodeling [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA]; go_process: GO:0043486 - histone exchange [Evidence IEA] AKAW2_11179A COG:Q; EggNog:ENOG410PW4T; InterPro:IPR001128,IPR002401,IPR036396; PFAM:PF00067; TransMembrane:2 (i12-33o45-66i); go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_11180S COG:S; EggNog:ENOG410PYN6; InterPro:IPR024368 AKAW2_11181A SECRETED:SignalP(1-20) AKAW2_11183S COG:K; EggNog:ENOG410Q1GW AKAW2_11184A BUSCO:EOG09261CQG; COG:J; EggNog:ENOG410PFF1; InterPro:IPR006195,IPR012340,IPR004365,IPR004364, IPR004522,IPR002312; PFAM:PF00152,PF01336; go_function: GO:0000166 - nucleotide binding [Evidence IEA]; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0004812 - aminoacyl-tRNA ligase activity [Evidence IEA]; go_function: GO:0004816 - asparagine-tRNA ligase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006418 - tRNA aminoacylation for protein translation [Evidence IEA]; go_process: GO:0006421 - asparaginyl-tRNA aminoacylation [Evidence IEA] AKAW2_11185S BUSCO:EOG09261ZFN; COG:A; EggNog:ENOG410PGH9; InterPro:IPR034195,IPR000504,IPR035979,IPR012677, IPR039171,IPR018835; PFAM:PF10378,PF00076; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0003723 - RNA binding [Evidence IEA] AKAW2_11186S COG:S; EggNog:ENOG410PSR4; InterPro:IPR040150,IPR013883; PFAM:PF08574; go_process: GO:0006606 - protein import into nucleus [Evidence IEA] AKAW2_11187A COG:S; EggNog:ENOG410PXAF AKAW2_11188A COG:S; EggNog:ENOG410PWSE AKAW2_11189A CAZy:GT69; COG:S; EggNog:ENOG410PKUE; InterPro:IPR021047; PFAM:PF11735; TransMembrane:1 (i50-71o) AKAW2_11190S COG:S; EggNog:ENOG410PQS6; InterPro:IPR009784; PFAM:PF07081 AKAW2_11191S COG:U; EggNog:ENOG410QE3C; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:13 (i64-81o101-121i133-154o166-184i193-213o225-247i281- 300o312-330i351-370o390-411i418-438o444-464i559-577o); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_11192S COG:Z; EggNog:ENOG410PH0N; InterPro:IPR005225,IPR001806,IPR027417,IPR003578; PFAM:PF08477,PF00071; go_function: GO:0003924 - GTPase activity [Evidence IEA]; go_function: GO:0005525 - GTP binding [Evidence IEA]; go_process: GO:0007264 - small GTPase mediated signal transduction [Evidence IEA] AKAW2_11193A COG:E; EggNog:ENOG410PI69; InterPro:IPR020855,IPR023696,IPR006035; PFAM:PF00491; SECRETED:SignalP(1-20); go_function: GO:0016813 - hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines [Evidence IEA]; go_function: GO:0046872 - metal ion binding [Evidence IEA] AKAW2_11194S COG:H; EggNog:ENOG410PFCF; InterPro:IPR000794,IPR016039,IPR018201,IPR017568, IPR014030,IPR014031,IPR020841; PFAM:PF00109,PF02801; go_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein] synthase activity [Evidence IEA]; go_function: GO:0016746 - transferase activity, transferring acyl groups [Evidence IEA]; go_function: GO:0016747 - transferase activity, transferring acyl groups other than amino-acyl groups [Evidence IEA]; go_process: GO:0006633 - fatty acid biosynthetic process [Evidence IEA] AKAW2_11195S COG:B; EggNog:ENOG410PIIX; InterPro:IPR013243,IPR037804; PFAM:PF08313; go_component: GO:0000124 - SAGA complex [Evidence IEA] AKAW2_11196S BUSCO:EOG09262K8L; COG:A; EggNog:ENOG410PG3F; InterPro:IPR017075,IPR001339,IPR012340,IPR013846; PFAM:PF03919,PF01068,PF01331; go_component: GO:0031533 - mRNA cap methyltransferase complex [Evidence IEA]; go_function: GO:0004484 - mRNA guanylyltransferase activity [Evidence IEA]; go_process: GO:0006370 - 7-methylguanosine mRNA capping [Evidence IEA] AKAW2_11197A COG:S; EggNog:ENOG410PQHG; InterPro:IPR019481; PFAM:PF10419 AKAW2_11198S COG:S; EggNog:ENOG410PIDW; InterPro:IPR009291; SECRETED:SignalP(1-38) AKAW2_11199A COG:T; EggNog:ENOG410PK02; InterPro:IPR019819,IPR019826,IPR002018,IPR029058; MEROPS:MER0033240; PFAM:PF00135; SECRETED:SignalP(1-18) AKAW2_11200S COG:S; EggNog:ENOG410PU7B; TransMembrane:7 (o22-42i54-76o107-127i134-156o176-203i215-235o247-272i) AKAW2_11201A COG:B; EggNog:ENOG410PHW2; InterPro:IPR019787,IPR019786,IPR011011,IPR001965, IPR001138,IPR003347,IPR041070,IPR013083; PFAM:PF13621,PF00628,PF02373; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_11202S COG:A; EggNog:ENOG410PP6T; InterPro:IPR000504,IPR034150,IPR035979,IPR012677; PFAM:PF13893,PF00076; go_function: GO:0003676 - nucleic acid binding [Evidence IEA] AKAW2_11203S COG:A; EggNog:ENOG410PMV3; InterPro:IPR002415,IPR029064,IPR018492,IPR004038; PFAM:PF01248; go_component: GO:0005730 - nucleolus [Evidence IEA]; go_function: GO:0003723 - RNA binding [Evidence IEA] AKAW2_11204S COG:S; EggNog:ENOG410PKQ2; InterPro:IPR022127; PFAM:PF12400; SECRETED:SignalP(1-24); TransMembrane:5 (n4-15c33/34o71-93i114-136o148-172i207-227o247-268i) AKAW2_11205S COG:A; EggNog:ENOG410PGJX; InterPro:IPR015943,IPR001680,IPR036322,IPR017986; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_11206A SECRETED:SignalP(1-20) AKAW2_11207A COG:G; EggNog:ENOG410PG3C; InterPro:IPR001312,IPR019807,IPR022673,IPR022672, IPR043129; PFAM:PF00349,PF03727; go_function: GO:0004396 - hexokinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0005536 - glucose binding [Evidence IEA]; go_function: GO:0016773 - phosphotransferase activity, alcohol group as acceptor [Evidence IEA]; go_process: GO:0001678 - cellular glucose homeostasis [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA]; go_process: GO:0006096 - glycolytic process [Evidence IEA] AKAW2_11209A COG:B,K; EggNog:ENOG410Q10R; InterPro:IPR017328,IPR026590,IPR026591,IPR029035, IPR003000; PFAM:PF02146; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_function: GO:0017136 - NAD-dependent histone deacetylase activity [Evidence IEA]; go_function: GO:0070403 - NAD+ binding [Evidence IEA] AKAW2_11208S COG:U; EggNog:ENOG410PG81; InterPro:IPR013167; PFAM:PF08318 AKAW2_11210A COG:P; EggNog:ENOG410PFGK; InterPro:IPR024041,IPR018047,IPR001905,IPR029020; PFAM:PF00909; TransMembrane:11 (o51-71i83-101o141-162i169-193o205-227i239-259o271- 292i299-317o323-341i362-383o403-428i); go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0008519 - ammonium transmembrane transporter activity [Evidence IEA]; go_process: GO:0015696 - ammonium transport [Evidence IEA]; go_process: GO:0072488 - ammonium transmembrane transport [Evidence IEA] AKAW2_11212A COG:P; EggNog:ENOG410PIJI; InterPro:IPR006068,IPR018303,IPR023298,IPR023299, IPR001757,IPR004014,IPR036412,IPR008250; PFAM:PF00689,PF13246,PF00122,PF00690,PF00702; TransMembrane:8 (i95-113o119-135i349-368o374-403i902-922o942-962i983- 1003o1015-1034i); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0000166 - nucleotide binding [Evidence IEA] AKAW2_11213S COG:D; EggNog:ENOG410PG96; InterPro:IPR036390,IPR039781,IPR006909,IPR006910, IPR023093; PFAM:PF04824,PF04825; go_component: GO:0008278 - cohesin complex [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0007062 - sister chromatid cohesion [Evidence IEA] AKAW2_11214S COG:G; EggNog:ENOG410PHC0; InterPro:IPR005829,IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:11 (o113-137i149-168o180-198i210-232o269-290i345-367o379- 399i430-452o458-482i494-515o521-543i); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_11215S COG:K; EggNog:ENOG410PGKG; InterPro:IPR036864,IPR001138; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_11216A COG:S; EggNog:ENOG410PZ49; SECRETED:SignalP(1-20) AKAW2_11217S COG:F; EggNog:ENOG410PFKK; InterPro:IPR022310,IPR022955,IPR029062,IPR017926, IPR025777,IPR004739,IPR001674,IPR014729; MEROPS:MER0045886; PFAM:PF00117,PF00958; go_function: GO:0003922 - GMP synthase (glutamine-hydrolyzing) activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016462 - pyrophosphatase activity [Evidence IEA]; go_process: GO:0006164 - purine nucleotide biosynthetic process [Evidence IEA]; go_process: GO:0006177 - GMP biosynthetic process [Evidence IEA] AKAW2_11218S BUSCO:EOG092659OC; COG:H; EggNog:ENOG410PQKB; InterPro:IPR015865,IPR023465,IPR023468; PFAM:PF01687; go_function: GO:0008531 - riboflavin kinase activity [Evidence IEA]; go_process: GO:0009231 - riboflavin biosynthetic process [Evidence IEA] AKAW2_11219S COG:Q; EggNog:ENOG410Q2HH AKAW2_11220S BUSCO:EOG092628A0; COG:O; EggNog:ENOG410PJD1; InterPro:IPR007676; PFAM:PF04597; SECRETED:SignalP(1-24); TransMembrane:1 (n4-15c24/25o478-499i); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_process: GO:0006486 - protein glycosylation [Evidence IEA] AKAW2_11221S BUSCO:EOG09260E8K; COG:E; EggNog:ENOG410QE6V; InterPro:IPR036291,IPR028971,IPR016210,IPR006096; PFAM:PF00208; go_function: GO:0004352 - glutamate dehydrogenase (NAD+) activity [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0006520 - cellular amino acid metabolic process [Evidence IEA]; go_process: GO:0019551 - glutamate catabolic process to 2-oxoglutarate [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_11222A COG:S; EggNog:ENOG410PIHE; InterPro:IPR011990; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_11223S BUSCO:EOG09264XLN; COG:J; EggNog:ENOG410PQXB; InterPro:IPR036870,IPR001648; PFAM:PF01084; go_component: GO:0005840 - ribosome [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_process: GO:0006412 - translation [Evidence IEA] AKAW2_11224S BUSCO:EOG092619L1; COG:Z; EggNog:ENOG410PI4U; InterPro:IPR024977,IPR036322,IPR015943,IPR001680, IPR019775,IPR020472,IPR017986; PFAM:PF12894,PF00400; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_11225S COG:S; EggNog:ENOG410PI9M; InterPro:IPR023244; PFAM:PF13515; TransMembrane:11 (o104-122i150-175o181-204i211-228o248-268i648-665o677- 694i701-719o725-743i750-769o789-812i) AKAW2_11226S COG:K; EggNog:ENOG410PM83; InterPro:IPR024738; PFAM:PF12767; go_component: GO:0070461 - SAGA-type complex [Evidence IEA] AKAW2_11227A COG:A; EggNog:ENOG410PJ5I; InterPro:IPR011990,IPR027108,IPR010491,IPR019734, IPR003107,IPR013026; PFAM:PF13432,PF06424,PF13428,PF14559; TransMembrane:1 (i129-146o); go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0000398 - mRNA splicing, via spliceosome [Evidence IEA]; go_process: GO:0006396 - RNA processing [Evidence IEA] AKAW2_11228S BUSCO:EOG09263720; COG:A; EggNog:ENOG410PHZA; InterPro:IPR029063,IPR020598,IPR001737,IPR011530, IPR020596; PFAM:PF00398,PF13649,PF08241; go_function: GO:0000179 - rRNA (adenine-N6,N6-)-dimethyltransferase activity [Evidence IEA]; go_function: GO:0008649 - rRNA methyltransferase activity [Evidence IEA]; go_process: GO:0000154 - rRNA modification [Evidence IEA]; go_process: GO:0006364 - rRNA processing [Evidence IEA] AKAW2_11229A BUSCO:EOG09261YLQ; COG:U; EggNog:ENOG410PHR5; InterPro:IPR035969,IPR000195; PFAM:PF00566 AKAW2_11230S COG:A; EggNog:ENOG410PIPU; InterPro:IPR000504,IPR012677,IPR035979,IPR034156; PFAM:PF00076; go_function: GO:0003676 - nucleic acid binding [Evidence IEA] AKAW2_11231A COG:S; EggNog:ENOG410PIYC; InterPro:IPR032800,IPR010308,IPR040241; PFAM:PF06011,PF14558; SECRETED:SignalP(1-22); TransMembrane:7 (n6-17c22/23o349-380i401-421o427-449i489-509o515-534i546- 565o577-606i) AKAW2_11232A COG:G; EggNog:ENOG410QDI7; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (o52-70i91-112o118-140i147-167o179-198i210-230o282- 303i315-335o341-360i367-390o402-422i434-456o); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_11233A COG:S; EggNog:ENOG410PM2J; InterPro:IPR042183,IPR036148,IPR042188,IPR005656; PFAM:PF03972; go_function: GO:0016829 - lyase activity [Evidence IEA] AKAW2_11234A COG:S; EggNog:ENOG410PQA6; InterPro:IPR010756; PFAM:PF07052 AKAW2_11235S BUSCO:EOG09262MOO; COG:B; EggNog:ENOG410PFT0; InterPro:IPR004000,IPR043129; PFAM:PF00022 AKAW2_11236A COG:S; EggNog:ENOG410PPVF AKAW2_11237A COG:S; EggNog:ENOG410PQ42; InterPro:IPR007219; PFAM:PF04082; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA] AKAW2_11238S BUSCO:EOG09264GMT; COG:L; EggNog:ENOG410PGX3; InterPro:IPR002043,IPR036895,IPR018085,IPR005122; PFAM:PF03167; go_function: GO:0004844 - uracil DNA N-glycosylase activity [Evidence IEA]; go_function: GO:0016799 - hydrolase activity, hydrolyzing N-glycosyl compounds [Evidence IEA]; go_process: GO:0006281 - DNA repair [Evidence IEA]; go_process: GO:0006284 - base-excision repair [Evidence IEA] AKAW2_11239A COG:O; EggNog:ENOG410PHME; InterPro:IPR017937,IPR005788,IPR036249,IPR005792, IPR013766; PFAM:PF00085,PF01216,PF13848; SECRETED:SignalP(1-20); go_function: GO:0003756 - protein disulfide isomerase activity [Evidence IEA] AKAW2_11240A COG:P; EggNog:ENOG410PICK; InterPro:IPR024671,IPR020846,IPR036259; PFAM:PF07690,PF11700; TransMembrane:12 (i38-61o129-148i160-179o185-205i291-311o323-342i383- 408o420-440i452-471o491-510i522-545o551-572i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA] AKAW2_11241S BUSCO:EOG09260NAN; COG:K; EggNog:ENOG410PJBX; InterPro:IPR013947; PFAM:PF08638; go_component: GO:0016592 - mediator complex [Evidence IEA]; go_function: GO:0003712 - transcription coregulator activity [Evidence IEA]; go_process: GO:0006357 - regulation of transcription by RNA polymerase II [Evidence IEA] AKAW2_11242A COG:L; EggNog:ENOG410PFPN; InterPro:IPR007185,IPR016266; PFAM:PF04042; go_component: GO:0008622 - epsilon DNA polymerase complex [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_process: GO:0006260 - DNA replication [Evidence IEA]; go_process: GO:0006261 - DNA-dependent DNA replication [Evidence IEA] AKAW2_11243S COG:B,D; EggNog:ENOG410PHY4; InterPro:IPR011990,IPR019544; PFAM:PF10516; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_11244A COG:S; EggNog:ENOG410PPSW; InterPro:IPR034751,IPR004910,IPR039058; PFAM:PF03226 AKAW2_11245A BUSCO:EOG0926357F; COG:A; EggNog:ENOG410PI16; InterPro:IPR025829,IPR014891,IPR001878,IPR036875, IPR033489,IPR013083; PFAM:PF13696,PF08783; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_function: GO:0061630 - ubiquitin protein ligase activity [Evidence IEA]; go_process: GO:0006397 - mRNA processing [Evidence IEA]; go_process: GO:0016567 - protein ubiquitination [Evidence IEA] AKAW2_11246S COG:F; EggNog:ENOG410PGCY; InterPro:IPR002125,IPR035105,IPR027417,IPR016193, IPR016192,IPR015517; PFAM:PF14437,PF00383; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_11247S BUSCO:EOG09261NLY; COG:E; EggNog:ENOG410PFI1; InterPro:IPR011060,IPR004651,IPR029062,IPR006062, IPR017926,IPR014640,IPR010139,IPR013785; MEROPS:MER0065588; PFAM:PF01174,PF00117,PF00977; go_function: GO:0000107 - imidazoleglycerol-phosphate synthase activity [Evidence IEA]; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0016763 - transferase activity, transferring pentosyl groups [Evidence IEA]; go_function: GO:0016833 - oxo-acid-lyase activity [Evidence IEA]; go_process: GO:0000105 - histidine biosynthetic process [Evidence IEA] AKAW2_11248S COG:H; EggNog:ENOG410PG9W; InterPro:IPR035985,IPR000594,IPR042523,IPR042522, IPR032197,IPR006285; PFAM:PF16420,PF00899; go_component: GO:0005737 - cytoplasm [Evidence IEA]; go_function: GO:0008641 - ubiquitin-like modifier activating enzyme activity [Evidence IEA]; go_process: GO:0006914 - autophagy [Evidence IEA] AKAW2_11249A COG:A; EggNog:ENOG410PH9V; InterPro:IPR015507,IPR002877,IPR029063; PFAM:PF01728; go_function: GO:0008168 - methyltransferase activity [Evidence IEA]; go_process: GO:0001510 - RNA methylation [Evidence IEA]; go_process: GO:0032259 - methylation [Evidence IEA] AKAW2_11250S BUSCO:EOG09264R0D; COG:O; EggNog:ENOG410PHIV; InterPro:IPR036249,IPR021149; PFAM:PF04756; SECRETED:SignalP(1-21); TransMembrane:4 (n3-14c21/22o177-197i209-228o262-280i292-312o) AKAW2_11251S COG:D; EggNog:ENOG410PFSS; InterPro:IPR007594; PFAM:PF04506; TransMembrane:14 (i12-32o44-66i117-137o149-173i185-206o218-240i261-283o303- 321i359-378o398-419i431-449o461-479i500-520o526-543i); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_process: GO:0006488 - dolichol-linked oligosaccharide biosynthetic process [Evidence IEA] AKAW2_11252A BUSCO:EOG092625P1; COG:A; EggNog:ENOG410PGQU; InterPro:IPR027417,IPR001650,IPR014001,IPR011545, IPR000629; PFAM:PF04851,PF00270,PF00271; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA] AKAW2_11253A COG:Q; EggNog:ENOG410PFM9; InterPro:IPR013154,IPR014189,IPR036291,IPR011032, IPR020843; PFAM:PF00107,PF13602; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_11254A BUSCO:EOG09262387; COG:L; EggNog:ENOG410PGI7; InterPro:IPR031657,IPR004591,IPR013955,IPR004365, IPR012340,IPR007199; PFAM:PF01336,PF04057,PF08646,PF16900; go_component: GO:0005634 - nucleus [Evidence IEA]; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_process: GO:0006260 - DNA replication [Evidence IEA]; go_process: GO:0006281 - DNA repair [Evidence IEA]; go_process: GO:0006310 - DNA recombination [Evidence IEA] AKAW2_11255S COG:O; EggNog:ENOG410PFVY; InterPro:IPR038765,IPR016652,IPR001607,IPR009060, IPR018200,IPR001394,IPR015940,IPR041432,IPR028889, IPR013083; MEROPS:MER0001881; PFAM:PF13423,PF02148,PF00443,PF00627,PF17807; go_function: GO:0004843 - thiol-dependent ubiquitin-specific protease activity [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006511 - ubiquitin-dependent protein catabolic process [Evidence IEA]; go_process: GO:0016579 - protein deubiquitination [Evidence IEA] AKAW2_11256S COG:S; EggNog:ENOG410PMWY; InterPro:IPR009057,IPR007526; PFAM:PF04433; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_11257S COG:D,K,T; EggNog:ENOG410PG9Y; InterPro:IPR005045; PFAM:PF03381; TransMembrane:2 (i53-74o342-367i); go_component: GO:0016020 - membrane [Evidence IEA] AKAW2_11258S COG:O; EggNog:ENOG410PIAE; InterPro:IPR008754,IPR024079; MEROPS:MER0011122; PFAM:PF05572; SECRETED:SignalP(1-25); go_function: GO:0008237 - metallopeptidase activity [Evidence IEA] AKAW2_11259A BUSCO:EOG09260K4V; COG:K; EggNog:ENOG410PGE8; InterPro:IPR000994,IPR011993,IPR013953,IPR029148, IPR029149,IPR040258,IPR036005,IPR013719; MEROPS:MER0026495; PFAM:PF08512,PF08644,PF14826,PF00557; go_component: GO:0035101 - FACT complex [Evidence IEA] AKAW2_11260S COG:C; EggNog:ENOG410PJN4; InterPro:IPR018108,IPR023395; PFAM:PF00153; TransMembrane:2 (i111-133o153-173i) AKAW2_11261S COG:G; EggNog:ENOG410PGCG; InterPro:IPR005829,IPR005828,IPR003663,IPR036259, IPR020846; PFAM:PF00083,PF07690; TransMembrane:11 (i20-40o60-80i92-111o117-138i150-171o183-203i269-293o305- 327i334-355o367-387i430-449o); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_11262S CAZy:GT39; COG:O; EggNog:ENOG410PGRQ; InterPro:IPR036300,IPR027005,IPR016093,IPR003342, IPR032421; PFAM:PF16192,PF02815,PF02366; TransMembrane:10 (o54-72i103-125o145-163i194-215o227-260i281-306o601- 622i643-663o669-687i699-721o); go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0000030 - mannosyltransferase activity [Evidence IEA]; go_process: GO:0006493 - protein O-linked glycosylation [Evidence IEA] AKAW2_11263A COG:U; EggNog:ENOG410PKSE; InterPro:IPR001806,IPR027417,IPR005225; PFAM:PF00009,PF00025; go_function: GO:0003924 - GTPase activity [Evidence IEA]; go_function: GO:0005525 - GTP binding [Evidence IEA] AKAW2_11264A COG:S; EggNog:ENOG410PRXY; TransMembrane:1 (o597-615i) AKAW2_11265A COG:S; EggNog:ENOG410PKDI; InterPro:IPR018170,IPR020471,IPR036812,IPR023210; PFAM:PF00248; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_11266S COG:H; EggNog:ENOG410PFM8; InterPro:IPR003846; PFAM:PF02696 AKAW2_11267A COG:O; EggNog:ENOG410PPNC; InterPro:IPR036875,IPR001878; PFAM:PF00098; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA] AKAW2_11268A COG:S; EggNog:ENOG410PJPC; InterPro:IPR001810,IPR036322,IPR036047,IPR001680, IPR017986; PFAM:PF00646,PF12937; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_11269S COG:S; EggNog:ENOG410PSHE; InterPro:IPR033316,IPR013882; PFAM:PF08573; go_function: GO:0004519 - endonuclease activity [Evidence IEA]; go_process: GO:0006281 - DNA repair [Evidence IEA] AKAW2_11270S COG:U; EggNog:ENOG410PIYK; InterPro:IPR013919; PFAM:PF08610 AKAW2_11271A BUSCO:EOG09263OWL; COG:L; EggNog:ENOG410PJ2H; InterPro:IPR012337,IPR024567,IPR001352,IPR004649, IPR023160,IPR036397; PFAM:PF01351; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0003723 - RNA binding [Evidence IEA]; go_function: GO:0004523 - RNA-DNA hybrid ribonuclease activity [Evidence IEA]; go_process: GO:0016070 - RNA metabolic process [Evidence IEA] AKAW2_11272S COG:O; EggNog:ENOG410PP80; InterPro:IPR028929,IPR025974,IPR028386,IPR014710, IPR011051; PFAM:PF15624,PF07883,PF11699; go_component: GO:0000776 - kinetochore [Evidence IEA]; go_function: GO:0019237 - centromeric DNA binding [Evidence IEA]; go_process: GO:0051382 - kinetochore assembly [Evidence IEA] AKAW2_11273A BUSCO:EOG0926505R; COG:O; EggNog:ENOG410PF90; InterPro:IPR029071,IPR036859,IPR000938,IPR000626; PFAM:PF14560,PF01302; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_11274S BUSCO:EOG09264DIM; COG:Q; EggNog:ENOG410PMYZ; InterPro:IPR029063,IPR013216,IPR032873; PFAM:PF13649,PF13489,PF08241; go_function: GO:0008168 - methyltransferase activity [Evidence IEA]; go_function: GO:0016300 - tRNA (uracil) methyltransferase activity [Evidence IEA]; go_process: GO:0002098 - tRNA wobble uridine modification [Evidence IEA] AKAW2_11275A COG:K; EggNog:ENOG410PKQ5; InterPro:IPR001005,IPR009057,IPR017930,IPR017877; PFAM:PF00249 AKAW2_11277S TransMembrane:1 (i71-93o) AKAW2_11278S COG:O; EggNog:ENOG410PIZR; InterPro:IPR038765,IPR037798,IPR001394,IPR028889; MEROPS:MER0004311; PFAM:PF13423,PF00443; TransMembrane:1 (i48-69o); go_function: GO:0004843 - thiol-dependent ubiquitin-specific protease activity [Evidence IEA]; go_process: GO:0016578 - histone deubiquitination [Evidence IEA]; go_process: GO:0016579 - protein deubiquitination [Evidence IEA] AKAW2_11279S COG:S; EggNog:ENOG410PRMT; InterPro:IPR007527; go_function: GO:0008270 - zinc ion binding [Evidence IEA] AKAW2_11280A BUSCO:EOG09263KRO; COG:O; EggNog:ENOG410PHXE; InterPro:IPR024969,IPR037518,IPR033858,IPR000555; MEROPS:MER0030134; PFAM:PF13012,PF01398; go_component: GO:0005838 - proteasome regulatory particle [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_function: GO:0008237 - metallopeptidase activity [Evidence IEA]; go_function: GO:0070122 - isopeptidase activity [Evidence IEA] AKAW2_11281S COG:F; EggNog:ENOG410PG6Q; InterPro:IPR027417,IPR006259,IPR000850,IPR028587, IPR033690,IPR007862; PFAM:PF05191,PF00406,PF13238,PF13207; go_function: GO:0004017 - adenylate kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016776 - phosphotransferase activity, phosphate group as acceptor [Evidence IEA]; go_function: GO:0019205 - nucleobase-containing compound kinase activity [Evidence IEA]; go_process: GO:0006139 - nucleobase-containing compound metabolic process [Evidence IEA]; go_process: GO:0006172 - ADP biosynthetic process [Evidence IEA] AKAW2_11282A COG:G,Q; EggNog:ENOG410PKW7; InterPro:IPR036291,IPR000683; PFAM:PF01408; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA] AKAW2_11283A COG:A; EggNog:ENOG410QE1P; InterPro:IPR006569,IPR021605,IPR008942; PFAM:PF04818; go_component: GO:0005849 - mRNA cleavage factor complex [Evidence IEA]; go_process: GO:0006369 - termination of RNA polymerase II transcription [Evidence IEA]; go_process: GO:0006378 - mRNA polyadenylation [Evidence IEA]; go_process: GO:0006379 - mRNA cleavage [Evidence IEA] AKAW2_11284S COG:S; EggNog:ENOG410PTV0; InterPro:IPR037045; SECRETED:SignalP(1-18) AKAW2_11285S COG:S; EggNog:ENOG410PQX0; InterPro:IPR043936,IPR036872; PFAM:PF19047; go_process: GO:0030705 - cytoskeleton-dependent intracellular transport [Evidence IEA] AKAW2_11286A BUSCO:EOG09262CUO; COG:H; EggNog:ENOG410PIF2; InterPro:IPR018375,IPR001260,IPR036406; PFAM:PF01218; TransMembrane:1 (i54-72o); go_function: GO:0004109 - coproporphyrinogen oxidase activity [Evidence IEA]; go_process: GO:0006779 - porphyrin-containing compound biosynthetic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_11287S BUSCO:EOG09265BTA; COG:U; EggNog:ENOG410PNV6; InterPro:IPR029071,IPR004241; PFAM:PF04110,PF02991 AKAW2_11288S BUSCO:EOG09263JTO; COG:C; EggNog:ENOG410PF7V; InterPro:IPR018108,IPR023395; PFAM:PF00153 AKAW2_11289S COG:S; EggNog:ENOG410Q2BD; InterPro:IPR024242; PFAM:PF11654; TransMembrane:1 (o6-25i); go_process: GO:0009306 - protein secretion [Evidence IEA] AKAW2_11290A COG:O; EggNog:ENOG410PFQW; InterPro:IPR018181,IPR029047,IPR029048,IPR013126, IPR043129; PFAM:PF00012,PF06723 AKAW2_11291S COG:S; EggNog:ENOG410Q06F; InterPro:IPR019098; PFAM:PF09649 AKAW2_11292S COG:U; EggNog:ENOG410PNJI; InterPro:IPR039899,IPR039897; TransMembrane:1 (i148-169o); go_component: GO:0030173 - integral component of Golgi membrane [Evidence IEA]; go_process: GO:0015031 - protein transport [Evidence IEA] AKAW2_11293A COG:S; EggNog:ENOG410PY2Q; InterPro:IPR008402; PFAM:PF05841; go_component: GO:0005680 - anaphase-promoting complex [Evidence IEA]; go_process: GO:0030071 - regulation of mitotic metaphase/anaphase transition [Evidence IEA]; go_process: GO:0031145 - anaphase-promoting complex-dependent catabolic process [Evidence IEA] AKAW2_11294S BUSCO:EOG092600T9; COG:E; EggNog:ENOG410PGFW; InterPro:IPR028261,IPR023753,IPR029055,IPR017932, IPR002932,IPR009051,IPR006982,IPR002489,IPR013785, IPR036188,IPR036485,IPR012220,IPR006005; MEROPS:MER1054487; PFAM:PF07992,PF01645,PF13450,PF04898,PF00310, PF01493,PF14691; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0010181 - FMN binding [Evidence IEA]; go_function: GO:0015930 - glutamate synthase activity [Evidence IEA]; go_function: GO:0016040 - glutamate synthase (NADH) activity [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0016638 - oxidoreductase activity, acting on the CH-NH2 group of donors [Evidence IEA]; go_function: GO:0016639 - oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_function: GO:0051536 - iron-sulfur cluster binding [Evidence IEA]; go_process: GO:0006537 - glutamate biosynthetic process [Evidence IEA]; go_process: GO:0006807 - nitrogen compound metabolic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_11296A BUSCO:EOG092656IY; COG:S; EggNog:ENOG410PR9N; InterPro:IPR021475; PFAM:PF11326 AKAW2_11297S BUSCO:EOG092613R2; COG:A; EggNog:ENOG410PFI4; InterPro:IPR000504,IPR039627,IPR018850,IPR035979, IPR012677,IPR034260; PFAM:PF10443,PF00076; TransMembrane:1 (o295-315i); go_component: GO:0031305 - integral component of mitochondrial inner membrane [Evidence IEA]; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_process: GO:0000002 - mitochondrial genome maintenance [Evidence IEA] AKAW2_11298S COG:Q; EggNog:ENOG410PN22; InterPro:IPR001128,IPR002403,IPR036396; PFAM:PF00067; TransMembrane:1 (o23-43i); go_function: GO:0004497 - monooxygenase activity [Evidence IEA]; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_11299S COG:E; EggNog:ENOG410PIS1; InterPro:IPR020558,IPR000581,IPR037237,IPR042096; PFAM:PF00920; go_function: GO:0003824 - catalytic activity [Evidence IEA] AKAW2_11300S BUSCO:EOG09260S2Z; COG:S; EggNog:ENOG410PFNV; InterPro:IPR015943,IPR022100,IPR019775,IPR001680, IPR017986; PFAM:PF12894,PF12341,PF00400; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_11301S COG:S; EggNog:ENOG410PP99; InterPro:IPR031342; PFAM:PF17119 AKAW2_11302A COG:G; EggNog:ENOG410PK1M; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i12-33o75-97i109-127o133-154i166-187o199-221i263-283o303- 321i328-347o353-375i396-413o419-437i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_11303A COG:S; EggNog:ENOG410PNIX AKAW2_11304A COG:S; EggNog:ENOG410PS30; InterPro:IPR009072,IPR003958; PFAM:PF00808; antiSMASH:Cluster_1.16; go_function: GO:0046982 - protein heterodimerization activity [Evidence IEA] AKAW2_11305A COG:L; EggNog:ENOG410PKYA; InterPro:IPR015797,IPR000086; PFAM:PF00293; TransMembrane:1 (o417-438i); antiSMASH:Cluster_1.16; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_11306S COG:P; EggNog:ENOG410PFJD; InterPro:IPR003807,IPR018966,IPR004331; PFAM:PF09359,PF02656; TransMembrane:3 (o661-679i691-709o729-749i); antiSMASH:Cluster_1.16 AKAW2_11307A COG:S; EggNog:ENOG410PMH0; InterPro:IPR019402; PFAM:PF10277; TransMembrane:6 (i29-53o81-103i177-198o210-230i261-285o297-317i); antiSMASH:Cluster_1.16 AKAW2_11308A COG:Q; EggNog:ENOG410PW8P; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; SMCOG1005:Drug resistance transporter, EmrB/QacA; TransMembrane:14 (i49-75o87-106i118-137o143-164i176-198o210-229i241- 261o267-292i313-331o351-369i376-395o407-427i439-463o523- 542i); antiSMASH:Cluster_1.16; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_11309A COG:Q; EggNog:ENOG410PKS3; InterPro:IPR001128,IPR002401,IPR036396; PFAM:PF00067; SMCOG1034:cytochrome P450; TransMembrane:1 (o6-24i); antiSMASH:Cluster_1.16; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_11310S COG:T; EggNog:ENOG410Q226; InterPro:IPR017850,IPR039527,IPR002591,IPR037674; TransMembrane:14 (i12-30o456-475i487-506o512-529i536-554o574-592i604- 628o648-669i681-698o704-721i733-752o772-797i818-844o864- 883i); antiSMASH:Cluster_1.16; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0051377 - mannose-ethanolamine phosphotransferase activity [Evidence IEA]; go_process: GO:0006506 - GPI anchor biosynthetic process [Evidence IEA] AKAW2_11311A COG:S; EggNog:ENOG410PIV5; InterPro:IPR022742,IPR029058; PFAM:PF12697,PF12146; antiSMASH:Cluster_1.16 AKAW2_11312S COG:Q; EggNog:ENOG410PFKE; InterPro:IPR016036,IPR016035,IPR016039,IPR042104, IPR014030,IPR011032,IPR013968,IPR013154,IPR001227, IPR032821,IPR014031,IPR014043,IPR020806,IPR020807, IPR020843,IPR020841,IPR009081,IPR036736,IPR036291; PFAM:PF16197,PF08659,PF00550,PF02801,PF00698, PF13602,PF14765,PF00107,PF00109,PF08240; SMCOG1022:Beta-ketoacyl synthase; antiSMASH:Cluster_1.16; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0016740 - transferase activity [Evidence IEA]; go_function: GO:0016746 - transferase activity, transferring acyl groups [Evidence IEA]; go_function: GO:0031177 - phosphopantetheine binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_11313S COG:Q; EggNog:ENOG410PHMX; InterPro:IPR036249,IPR001853; PFAM:PF01323; antiSMASH:Cluster_1.16; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA] AKAW2_11314A COG:G; EggNog:ENOG410PHF2; InterPro:IPR013079,IPR013078,IPR027417,IPR001345, IPR003094,IPR029033; SMCOG1101:phosphoglycerate mutase; antiSMASH:Cluster_1.16; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0003873 - 6-phosphofructo-2-kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006000 - fructose metabolic process [Evidence IEA]; go_process: GO:0006003 - fructose 2,6-bisphosphate metabolic process [Evidence IEA] AKAW2_11315A COG:S; EggNog:ENOG410PQ17; TransMembrane:3 (i40-59o65-83i111-131o); antiSMASH:Cluster_1.16 AKAW2_11316S COG:C; EggNog:ENOG410PGNY; InterPro:IPR037458,IPR001199,IPR037396,IPR013785, IPR036400,IPR000262,IPR018506; PFAM:PF00173,PF01070; SECRETED:SignalP(1-30); antiSMASH:Cluster_1.16; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA] AKAW2_11317A antiSMASH:Cluster_1.16 AKAW2_11318A COG:S; EggNog:ENOG410PNAW; InterPro:IPR011009; PFAM:PF01636; antiSMASH:Cluster_1.16 AKAW2_11319S COG:S; EggNog:ENOG410PY96; InterPro:IPR003480,IPR023213; PFAM:PF02458; antiSMASH:Cluster_1.16; go_function: GO:0016747 - transferase activity, transferring acyl groups other than amino-acyl groups [Evidence IEA] AKAW2_11320A CAZy:GH3; COG:G; EggNog:ENOG410PVVB; InterPro:IPR017853,IPR036962,IPR002772,IPR036881, IPR026891,IPR013783,IPR001764; PFAM:PF14310,PF01915; SECRETED:SignalP(1-18); go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_11321S COG:L; EggNog:ENOG410PJMD; InterPro:IPR012337,IPR036397,IPR009027,IPR011320, IPR002156,IPR037056; PFAM:PF00075,PF01693; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0004523 - RNA-DNA hybrid ribonuclease activity [Evidence IEA] AKAW2_11322S COG:P; EggNog:ENOG410PJR5; InterPro:IPR006153,IPR038770; PFAM:PF00999; SECRETED:SignalP(1-24); TransMembrane:7 (n7-16c28/29o70-86i107-125o145-177i198-217o223-245i257- 279o306-326i); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0015299 - solute:proton antiporter activity [Evidence IEA]; go_process: GO:0006812 - cation transport [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_11323A BUSCO:EOG09260V8Q; COG:O; EggNog:ENOG410PIVR; InterPro:IPR038765,IPR001394,IPR018200,IPR028889; MEROPS:MER0005436; PFAM:PF13423,PF00443; go_function: GO:0004843 - thiol-dependent ubiquitin-specific protease activity [Evidence IEA]; go_process: GO:0006511 - ubiquitin-dependent protein catabolic process [Evidence IEA]; go_process: GO:0016579 - protein deubiquitination [Evidence IEA] AKAW2_11324A COG:O; EggNog:ENOG410PJY0; InterPro:IPR001841,IPR017907,IPR039739,IPR018957, IPR013083; PFAM:PF00097,PF13445; go_function: GO:0046872 - metal ion binding [Evidence IEA] AKAW2_11325S COG:I; EggNog:ENOG410PFUR; InterPro:IPR001171,IPR018083; PFAM:PF01222; TransMembrane:9 (i108-129o172-193i205-231o243-264i297-316o322-341i362- 386o398-414i478-498o); go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0016628 - oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor [Evidence IEA]; go_process: GO:0016126 - sterol biosynthetic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_11326S COG:G; EggNog:ENOG410PGQA; InterPro:IPR002925,IPR029058; PFAM:PF01738; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_11327S COG:S; EggNog:ENOG410PIP5; InterPro:IPR022057; PFAM:PF12271; TransMembrane:7 (i50-72o88-107i119-143o149-170i191-220o226-246i258-279o) AKAW2_11328A COG:S; EggNog:ENOG410PPSU; InterPro:IPR009598; PFAM:PF06726; TransMembrane:1 (n2-13c17/18o27-48i) AKAW2_11329S COG:S; EggNog:ENOG410PKKU; InterPro:IPR015943,IPR036322; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_11330A COG:A; EggNog:ENOG410PMF0; InterPro:IPR016193; go_function: GO:0003824 - catalytic activity [Evidence IEA] AKAW2_11331A COG:S; EggNog:ENOG410PHAD; InterPro:IPR013922,IPR036915; PFAM:PF08613,PF00134; go_function: GO:0019901 - protein kinase binding [Evidence IEA]; go_process: GO:0000079 - regulation of cyclin-dependent protein serine/threonine kinase activity [Evidence IEA] AKAW2_11332S COG:S; EggNog:ENOG410PG4B; InterPro:IPR038739,IPR000225,IPR011989,IPR016024; TransMembrane:1 (n4-11c16/17o889-906i); go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_11333S COG:G; EggNog:ENOG410PIGN; InterPro:IPR016477,IPR011009; PFAM:PF03881,PF01636 AKAW2_11334S COG:O; EggNog:ENOG410PKP1; InterPro:IPR005442,IPR036249,IPR040079,IPR036282, IPR010987,IPR004045; PFAM:PF13409,PF13417,PF13410,PF02798; go_component: GO:0005737 - cytoplasm [Evidence IEA]; go_function: GO:0004364 - glutathione transferase activity [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0006749 - glutathione metabolic process [Evidence IEA] AKAW2_11335S COG:D; EggNog:ENOG410PJ8K; InterPro:IPR006671,IPR036915,IPR013763,IPR043198; PFAM:PF00134; go_function: GO:0016538 - cyclin-dependent protein serine/threonine kinase regulator activity [Evidence IEA]; go_process: GO:0006357 - regulation of transcription by RNA polymerase II [Evidence IEA] AKAW2_11336A BUSCO:EOG09261W90; COG:I; EggNog:ENOG410PHHQ; InterPro:IPR000374,IPR016720; PFAM:PF01148; TransMembrane:8 (i70-87o93-117i129-149o169-186i198-216o222-248i260- 278o333-355i); go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0004605 - phosphatidate cytidylyltransferase activity [Evidence IEA]; go_function: GO:0016772 - transferase activity, transferring phosphorus-containing groups [Evidence IEA] AKAW2_11337S COG:L; EggNog:ENOG410PJ9I; InterPro:IPR022093; PFAM:PF12331 AKAW2_11339S BUSCO:EOG092651FJ; COG:J; EggNog:ENOG410PGZX; InterPro:IPR036986,IPR022801,IPR002942,IPR018079, IPR005709; PFAM:PF01479; go_component: GO:0015935 - small ribosomal subunit [Evidence IEA]; go_function: GO:0003723 - RNA binding [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_function: GO:0019843 - rRNA binding [Evidence IEA]; go_process: GO:0006412 - translation [Evidence IEA] AKAW2_11340S COG:S; EggNog:ENOG410PWRB AKAW2_11341A BUSCO:EOG09262Q8D; COG:C; EggNog:ENOG410PFYV; InterPro:IPR017597,IPR029061,IPR001017; PFAM:PF00676; go_component: GO:0043231 - intracellular membrane-bounded organelle [Evidence IEA]; go_function: GO:0004739 - pyruvate dehydrogenase (acetyl-transferring) activity [Evidence IEA]; go_function: GO:0016624 - oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor [Evidence IEA]; go_process: GO:0006086 - acetyl-CoA biosynthetic process from pyruvate [Evidence IEA] AKAW2_11343S COG:O; EggNog:ENOG410PFGQ; InterPro:IPR001841,IPR011993,IPR001849,IPR002035, IPR036465,IPR013083; PFAM:PF15411,PF13768,PF00092 AKAW2_11345S COG:S; EggNog:ENOG410Q2SF AKAW2_11346A COG:K; EggNog:ENOG410PFWM; InterPro:IPR036864,IPR021858,IPR001138; PFAM:PF00172,PF11951; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_11347S COG:S; EggNog:ENOG410PJCT; InterPro:IPR013761,IPR001849,IPR001660; PFAM:PF18016,PF00536,PF07647; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_11348S COG:M; EggNog:ENOG410PK0T; InterPro:IPR002110,IPR027417,IPR007111,IPR036770, IPR020683; PFAM:PF13857,PF05729,PF12796,PF13401,PF13606, PF13637,PF00023; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_11349A COG:U; EggNog:ENOG410PMQQ; InterPro:IPR042527,IPR007239,IPR042526; PFAM:PF04106; go_component: GO:0005737 - cytoplasm [Evidence IEA]; go_process: GO:0006914 - autophagy [Evidence IEA] AKAW2_11350S COG:S; EggNog:ENOG410Q2YD; InterPro:IPR038656,IPR000250,IPR013320; MEROPS:MER0001321; PFAM:PF01828; SECRETED:SignalP(1-19); go_function: GO:0004190 - aspartic-type endopeptidase activity [Evidence IEA]; go_process: GO:0006508 - proteolysis [Evidence IEA] AKAW2_11351A SECRETED:SignalP(1-17) AKAW2_11352A COG:K; EggNog:ENOG410PU72; InterPro:IPR036864,IPR001138; PFAM:PF00172; TransMembrane:1 (o344-363i); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_11353A COG:T; EggNog:ENOG410PPHK; InterPro:IPR008978,IPR007052,IPR037898; PFAM:PF04969 AKAW2_11354A COG:S; EggNog:ENOG410PPY3 AKAW2_11355A BUSCO:EOG09262SI7; COG:J; EggNog:ENOG410PH60; InterPro:IPR016435,IPR042263,IPR010014,IPR042265, IPR042264; PFAM:PF01866; go_process: GO:0017183 - peptidyl-diphthamide biosynthetic process from peptidyl-histidine [Evidence IEA] AKAW2_11356A COG:C; EggNog:ENOG410PM6E; InterPro:IPR034786,IPR016435,IPR001670,IPR039697; PFAM:PF13685,PF00465; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0018506 - maleylacetate reductase activity [Evidence IEA]; go_function: GO:0046872 - metal ion binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_11357A COG:Q; EggNog:ENOG410PNKZ; InterPro:IPR036291 AKAW2_11358A COG:S; EggNog:ENOG410PGDQ; InterPro:IPR015943,IPR036322; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_11359A CAZy:GH7; COG:G; EggNog:ENOG410PHJ4; InterPro:IPR037019,IPR001722,IPR013320; PFAM:PF00840; SECRETED:SignalP(1-17); go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_11360S COG:S; EggNog:ENOG410PGEP; InterPro:IPR029058 AKAW2_11361A COG:S; EggNog:ENOG410Q1TH AKAW2_11362A COG:S; EggNog:ENOG410PQ3H; InterPro:IPR025702; PFAM:PF13816 AKAW2_11363A COG:T; EggNog:ENOG410PK2U; InterPro:IPR004254; PFAM:PF03006; TransMembrane:7 (o264-284i296-316o336-356i363-379o391-410i422-444o464- 480i); go_component: GO:0016021 - integral component of membrane [Evidence IEA] AKAW2_11364S COG:U; EggNog:ENOG410PKP7; InterPro:IPR019163 AKAW2_11365S BUSCO:EOG092635DF; COG:M,O; EggNog:ENOG410PFJ8; InterPro:IPR019540; PFAM:PF10510; TransMembrane:2 (i43-60o514-533i); go_component: GO:0042765 - GPI-anchor transamidase complex [Evidence IEA]; go_process: GO:0016255 - attachment of GPI anchor to protein [Evidence IEA] AKAW2_11366A COG:S; EggNog:ENOG410PR29; SECRETED:SignalP(1-31); TransMembrane:1 (n16-26c31/32o226-249i) AKAW2_11367S COG:P; EggNog:ENOG410PNDY; InterPro:IPR036314,IPR036324,IPR019832; go_function: GO:0004784 - superoxide dismutase activity [Evidence IEA]; go_function: GO:0046872 - metal ion binding [Evidence IEA]; go_process: GO:0006801 - superoxide metabolic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_11368A COG:I; EggNog:ENOG410PR4K; InterPro:IPR005031,IPR023393; PFAM:PF03364 AKAW2_11369A COG:K; EggNog:ENOG410PW70; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; TransMembrane:1 (i256-274o); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_11370A COG:S; EggNog:ENOG410PIBR; InterPro:IPR029069 AKAW2_11371A InterPro:IPR036236,IPR013087; PFAM:PF00096 AKAW2_11372S COG:M; EggNog:ENOG410PY8W; InterPro:IPR002110,IPR020683,IPR036770; PFAM:PF13637,PF12796; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_11373A COG:I; EggNog:ENOG410PFBH; InterPro:IPR000873,IPR020845,IPR030310,IPR042099, IPR025110; PFAM:PF00501,PF13193; TransMembrane:3 (o12-31i117-140o273-296i); go_function: GO:0004467 - long-chain fatty acid-CoA ligase activity [Evidence IEA]; go_process: GO:0006633 - fatty acid biosynthetic process [Evidence IEA] AKAW2_11374A COG:E; EggNog:ENOG410PHWC; InterPro:IPR004839,IPR004838,IPR015424,IPR015421, IPR015422; PFAM:PF00155; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0030170 - pyridoxal phosphate binding [Evidence IEA]; go_process: GO:0009058 - biosynthetic process [Evidence IEA] AKAW2_11375S COG:Q; EggNog:ENOG410PGHX; InterPro:IPR043926,IPR000742,IPR027417,IPR003593, IPR017871,IPR003439,IPR013525; PFAM:PF01061,PF00005; SECRETED:SignalP(1-24); TransMembrane:7 (n6-17c24/25o317-339i838-859o871-893i914-939o951-974i981- 1001o1067-1090i); go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA]; go_function: GO:0042626 - ATPase-coupled transmembrane transporter activity [Evidence IEA] AKAW2_11376S COG:O,T,U; EggNog:ENOG410PPPS; InterPro:IPR033466,IPR003377; PFAM:PF03311; SECRETED:SignalP(1-25); TransMembrane:4 (n2-9c14/15o113-130i137-161o186-214i243-265o); go_process: GO:0016192 - vesicle-mediated transport [Evidence IEA] AKAW2_11377S BUSCO:EOG09262A6N; COG:A; EggNog:ENOG410PFEV; InterPro:IPR001680,IPR036322,IPR015943,IPR032847, IPR019775,IPR020472,IPR017986; PFAM:PF12894,PF00400; go_component: GO:0071013 - catalytic step 2 spliceosome [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0000398 - mRNA splicing, via spliceosome [Evidence IEA] AKAW2_11378A COG:S; EggNog:ENOG410PG6V; InterPro:IPR011992,IPR043145,IPR028846,IPR002048, IPR018247,IPR000433; PFAM:PF00036,PF13499,PF13202,PF00569; TransMembrane:1 (i16-36o); go_function: GO:0005509 - calcium ion binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA] AKAW2_11379A COG:D,P; EggNog:ENOG410PGV0; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:14 (i59-82o94-113i125-144o150-170i182-205o211-231i252- 269o275-299i320-344o356-376i383-408o414-435i447-467o526- 544i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_11380A COG:O; EggNog:ENOG410PI0E; InterPro:IPR000994,IPR002467,IPR036005,IPR001714, IPR031615; MEROPS:MER0001342; PFAM:PF15801,PF01753,PF00557; go_function: GO:0070006 - metalloaminopeptidase activity [Evidence IEA]; go_process: GO:0006508 - proteolysis [Evidence IEA] AKAW2_11381S COG:C; EggNog:ENOG410PFFH; InterPro:IPR027545,IPR036188,IPR002938; PFAM:PF01494; TransMembrane:1 (o459-479i); go_function: GO:0004502 - kynurenine 3-monooxygenase activity [Evidence IEA]; go_function: GO:0071949 - FAD binding [Evidence IEA]; go_process: GO:0006569 - tryptophan catabolic process [Evidence IEA]; go_process: GO:0019805 - quinolinate biosynthetic process [Evidence IEA] AKAW2_11382S COG:S; EggNog:ENOG410Q078 AKAW2_11383A COG:S; EggNog:ENOG410PKAG AKAW2_11384A BUSCO:EOG092650I8; COG:J; EggNog:ENOG410PPXD; InterPro:IPR035987,IPR000630; PFAM:PF00410; go_component: GO:0005840 - ribosome [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_process: GO:0006412 - translation [Evidence IEA] AKAW2_11385S COG:S; EggNog:ENOG410PPBB AKAW2_11386A COG:S; EggNog:ENOG410PNEI; InterPro:IPR002818,IPR029062; PFAM:PF01965 AKAW2_11387A COG:S; EggNog:ENOG410PSWT AKAW2_11389A COG:S; EggNog:ENOG410PP7R AKAW2_11390S COG:S; EggNog:ENOG410PIV1; InterPro:IPR026941,IPR021894,IPR001810,IPR036047; PFAM:PF12014,PF00646,PF12937; go_component: GO:0019005 - SCF ubiquitin ligase complex [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_function: GO:0030332 - cyclin binding [Evidence IEA]; go_process: GO:0006974 - cellular response to DNA damage stimulus [Evidence IEA]; go_process: GO:0031146 - SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [Evidence IEA]; go_process: GO:0031571 - mitotic G1 DNA damage checkpoint [Evidence IEA] AKAW2_11391A COG:S; EggNog:ENOG410PSHV; InterPro:IPR013726; PFAM:PF08520 AKAW2_11392S COG:G; EggNog:ENOG410PFMR; InterPro:IPR015793,IPR036918,IPR040442,IPR015795, IPR015806,IPR015813,IPR018209,IPR011037,IPR001697; PFAM:PF00224,PF02887; go_function: GO:0000287 - magnesium ion binding [Evidence IEA]; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0004743 - pyruvate kinase activity [Evidence IEA]; go_function: GO:0030955 - potassium ion binding [Evidence IEA]; go_process: GO:0006096 - glycolytic process [Evidence IEA] AKAW2_11393A BUSCO:EOG092600X0; COG:T; EggNog:ENOG410PG1R; InterPro:IPR017455,IPR002423,IPR027410,IPR011011, IPR002498,IPR000306,IPR027409,IPR027484,IPR013083; PFAM:PF01363,PF01504; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016307 - phosphatidylinositol phosphate kinase activity [Evidence IEA]; go_function: GO:0046872 - metal ion binding [Evidence IEA]; go_process: GO:0046488 - phosphatidylinositol metabolic process [Evidence IEA] AKAW2_11394S COG:S; EggNog:ENOG410PTU7 AKAW2_11395A COG:S; EggNog:ENOG410PINU; InterPro:IPR009571; PFAM:PF06687; TransMembrane:4 (o12-31i163-189o195-218i239-259o); go_component: GO:0005886 - plasma membrane [Evidence IEA] AKAW2_11396A CAZy:GH5; COG:G; EggNog:ENOG410PGYW; InterPro:IPR017853,IPR001547; PFAM:PF00150; SECRETED:SignalP(1-18); go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_process: GO:0071704 - organic substance metabolic process [Evidence IEA] AKAW2_11397A CAZy:CE16; COG:I; EggNog:ENOG410Q1TN; InterPro:IPR001087,IPR036514; PFAM:PF00657,PF13472; SECRETED:SignalP(1-24); go_function: GO:0016788 - hydrolase activity, acting on ester bonds [Evidence IEA] AKAW2_11398A COG:S; EggNog:ENOG410QE9U; InterPro:IPR036322,IPR015943,IPR019775,IPR001680, IPR017986; PFAM:PF00400; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_11399S COG:S; EggNog:ENOG410PFSH; InterPro:IPR028245,IPR027267; PFAM:PF13805 AKAW2_11400A COG:K; EggNog:ENOG410QDP5; InterPro:IPR004827; PFAM:PF07716; go_function: GO:0003700 - DNA-binding transcription factor activity [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_11401S COG:S; EggNog:ENOG410Q2YI; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; TransMembrane:2 (i560-580o639-660i); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_11402A BUSCO:EOG092640PR; COG:S; EggNog:ENOG410PGE3; InterPro:IPR013253,IPR033338; PFAM:PF15402,PF08317 AKAW2_11403S BUSCO:EOG092653NM; COG:J; EggNog:ENOG410PFMT; InterPro:IPR032440,IPR019979,IPR012340,IPR000266, IPR028333; PFAM:PF16205,PF00366; go_component: GO:0005840 - ribosome [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_process: GO:0006412 - translation [Evidence IEA] AKAW2_11404A COG:S; EggNog:ENOG410PXBH AKAW2_11405S COG:T,U; EggNog:ENOG410PG0M; InterPro:IPR013809,IPR011417,IPR014712,IPR008942; PFAM:PF01417,PF07651; go_component: GO:0030136 - clathrin-coated vesicle [Evidence IEA]; go_function: GO:0005543 - phospholipid binding [Evidence IEA]; go_function: GO:0005545 - 1-phosphatidylinositol binding [Evidence IEA]; go_function: GO:0030276 - clathrin binding [Evidence IEA]; go_process: GO:0048268 - clathrin coat assembly [Evidence IEA] AKAW2_11406S COG:S; EggNog:ENOG410PJVP; InterPro:IPR021858; PFAM:PF11951 AKAW2_11407A COG:S; EggNog:ENOG410PGY4; InterPro:IPR000791; PFAM:PF01184; TransMembrane:6 (i76-97o109-128i135-155o175-195i202-223o235-255i); go_component: GO:0016021 - integral component of membrane [Evidence IEA] AKAW2_11409S COG:G; EggNog:ENOG410PI9I; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i69-88o108-126i138-159o165-187i199-221o227-251i299- 323o335-355i362-383o395-415i422-443o455-476i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_11410A COG:C; EggNog:ENOG410PGTG; InterPro:IPR001155,IPR013785; PFAM:PF00724; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0010181 - FMN binding [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_11411A COG:S; EggNog:ENOG410PPF7 AKAW2_11412S COG:S; EggNog:ENOG410PJT9 AKAW2_11413S COG:B,L; EggNog:ENOG410PI7A; InterPro:IPR024977,IPR036322,IPR019015,IPR015943, IPR001680,IPR017986; PFAM:PF12894,PF09453,PF00400; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_11414A CAZy:GT20; COG:G; EggNog:ENOG410Q2VB; InterPro:IPR001830,IPR003337,IPR036412,IPR023214; PFAM:PF00982,PF02358; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_process: GO:0005992 - trehalose biosynthetic process [Evidence IEA] AKAW2_11415S CAZy:GT20; COG:H; EggNog:ENOG410Q22N; InterPro:IPR012766,IPR001830; PFAM:PF00982; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0003825 - alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity [Evidence IEA]; go_process: GO:0005992 - trehalose biosynthetic process [Evidence IEA] AKAW2_11416S COG:O; EggNog:ENOG410PJHM; InterPro:IPR018325,IPR038765,IPR002931; PFAM:PF03835,PF01841 AKAW2_11417A InterPro:IPR001452,IPR036028; TransMembrane:1 (o205-226i); go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_11418A COG:S; EggNog:ENOG410PU5W AKAW2_11419A TransMembrane:2 (i12-33o95-113i) AKAW2_11420A BUSCO:EOG09262WFG; COG:S; EggNog:ENOG410PM3F; InterPro:IPR002737; PFAM:PF01875 AKAW2_11421S COG:S; EggNog:ENOG410PU5A AKAW2_11422S COG:S; EggNog:ENOG410PS56; InterPro:IPR034110,IPR010920,IPR001163; PFAM:PF01423; go_component: GO:0031417 - NatC complex [Evidence IEA] AKAW2_11423S COG:T; EggNog:ENOG410PFNB; InterPro:IPR029052,IPR011159,IPR031675,IPR006186, IPR004843; PFAM:PF00149,PF16891; go_function: GO:0004724 - magnesium-dependent protein serine/threonine phosphatase activity [Evidence IEA]; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_11424A BUSCO:EOG09260VEY; COG:A; EggNog:ENOG410PFRR; InterPro:IPR015943,IPR001680,IPR036322,IPR017986; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_11425S COG:D; EggNog:ENOG410PI0X; InterPro:IPR036915,IPR006671,IPR004367,IPR039361, IPR013763; PFAM:PF02984,PF00134 AKAW2_11426A COG:L; EggNog:ENOG410PHAC; InterPro:IPR000212,IPR027417,IPR014016,IPR014017, IPR013986,IPR034739; PFAM:PF13361,PF13538,PF13245,PF00580; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0003678 - DNA helicase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_11427S COG:S; EggNog:ENOG410PJRU AKAW2_11428S TransMembrane:1 (o80-100i) AKAW2_11430S COG:U; EggNog:ENOG410PR82; InterPro:IPR033468,IPR019564; PFAM:PF10568,PF17171; TransMembrane:1 (o400-420i); go_component: GO:0001401 - SAM complex [Evidence IEA] AKAW2_11431A TransMembrane:3 (i7-30o42-64i76-93o) AKAW2_11432A COG:S; EggNog:ENOG410PRRT; InterPro:IPR038903; SECRETED:SignalP(1-20); go_component: GO:0005576 - extracellular region [Evidence IEA]; go_function: GO:0019863 - IgE binding [Evidence IEA] AKAW2_11433A COG:C; EggNog:ENOG410QDJN; InterPro:IPR039556,IPR018523,IPR015813,IPR040442; PFAM:PF13714; TransMembrane:1 (o232-251i); go_function: GO:0003824 - catalytic activity [Evidence IEA] AKAW2_11434S COG:B; EggNog:ENOG410PGMA; InterPro:IPR037138,IPR023696,IPR003084,IPR023801, IPR000286; PFAM:PF00850; go_function: GO:0004407 - histone deacetylase activity [Evidence IEA]; go_process: GO:0016575 - histone deacetylation [Evidence IEA] AKAW2_11435A BUSCO:EOG09264JW6; COG:A; EggNog:ENOG410PFTI; InterPro:IPR006811; PFAM:PF04722; go_component: GO:0005634 - nucleus [Evidence IEA]; go_function: GO:0004721 - phosphoprotein phosphatase activity [Evidence IEA]; go_process: GO:0006397 - mRNA processing [Evidence IEA] AKAW2_11436S COG:V; EggNog:ENOG410PMV9; InterPro:IPR000868,IPR036380; PFAM:PF00857 AKAW2_11437S COG:S; EggNog:ENOG410PN0C; InterPro:IPR022036; PFAM:PF12239 AKAW2_11438S BUSCO:EOG09262VQQ; COG:T; EggNog:ENOG410PH63; InterPro:IPR037239,IPR000648,IPR018494; PFAM:PF01237; go_function: GO:0008289 - lipid binding [Evidence IEA] AKAW2_11439A COG:L; EggNog:ENOG410PHTJ; InterPro:IPR038718,IPR000330,IPR027417,IPR001650, IPR014001,IPR029256; PFAM:PF04851,PF00176,PF00271,PF14773; go_function: GO:0005524 - ATP binding [Evidence IEA] AKAW2_11440S BUSCO:EOG0926407T; COG:J; EggNog:ENOG410PI30; InterPro:IPR020568,IPR027408,IPR001247,IPR036345; PFAM:PF01138 AKAW2_11441S COG:P; EggNog:ENOG410PP94; InterPro:IPR007274; PFAM:PF04145; TransMembrane:3 (o53-71i178-198o204-225i); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0005375 - copper ion transmembrane transporter activity [Evidence IEA]; go_process: GO:0035434 - copper ion transmembrane transport [Evidence IEA] AKAW2_11442A COG:O; EggNog:ENOG410PM2G; InterPro:IPR029000,IPR020892,IPR002130; PFAM:PF00160; go_function: GO:0003755 - peptidyl-prolyl cis-trans isomerase activity [Evidence IEA]; go_process: GO:0000413 - protein peptidyl-prolyl isomerization [Evidence IEA]; go_process: GO:0006457 - protein folding [Evidence IEA] AKAW2_11443A COG:S; EggNog:ENOG410PK5B; InterPro:IPR039892,IPR013724; PFAM:PF08518 AKAW2_11444A BUSCO:EOG092608ZS; COG:I; EggNog:ENOG410PH8V; InterPro:IPR023282,IPR002202,IPR023076,IPR023074, IPR025583,IPR000731,IPR009023,IPR004554,IPR009029; PFAM:PF00368,PF13323,PF12349; TransMembrane:7 (o243-264i271-291o297-317i374-393o399-421i485-506o607- 627i); go_function: GO:0004420 - hydroxymethylglutaryl-CoA reductase (NADPH) activity [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_function: GO:0016616 - oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Evidence IEA]; go_process: GO:0008299 - isoprenoid biosynthetic process [Evidence IEA]; go_process: GO:0015936 - coenzyme A metabolic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_11445S COG:S; EggNog:ENOG410PQD0; SECRETED:SignalP(1-26) AKAW2_11446S COG:T; EggNog:ENOG410PKCU; InterPro:IPR001452,IPR036028; PFAM:PF07653,PF00018,PF14604; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_11447S COG:O; EggNog:ENOG410PK8M; InterPro:IPR036249,IPR040079,IPR036282,IPR010987, IPR004045,IPR004046; PFAM:PF13409,PF00043,PF14497,PF13417,PF02798; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0006749 - glutathione metabolic process [Evidence IEA] AKAW2_11448A BUSCO:EOG09263WB5; COG:F; EggNog:ENOG410PJ8R; InterPro:IPR013809,IPR008942; PFAM:PF01417 AKAW2_11449A BUSCO:EOG09260GF5; COG:Z; EggNog:ENOG410PFE1; InterPro:IPR000048,IPR001936,IPR000593,IPR008936, IPR001715,IPR036872; PFAM:PF03836,PF00307,PF00616,PF00612; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0007165 - signal transduction [Evidence IEA]; go_process: GO:0043087 - regulation of GTPase activity [Evidence IEA] AKAW2_11450S COG:S; EggNog:ENOG410PSBE; InterPro:IPR009297; PFAM:PF06108 AKAW2_11451A COG:Q; EggNog:ENOG410PHD4; InterPro:IPR002347,IPR036291,IPR020904; PFAM:PF00106,PF13561,PF08659; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_11452S BUSCO:EOG09261T6U; COG:F; EggNog:ENOG410QE6G; InterPro:IPR013785,IPR000644,IPR001093,IPR005990, IPR015875; PFAM:PF00571,PF00478; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0003938 - IMP dehydrogenase activity [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0006164 - purine nucleotide biosynthetic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_11453S COG:L; EggNog:ENOG410PJUP; InterPro:IPR039121,IPR000086,IPR015797; PFAM:PF00293; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_11454S COG:J; EggNog:ENOG410PQS0; InterPro:IPR038579,IPR001931,IPR018279; PFAM:PF01249; go_component: GO:0005840 - ribosome [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_process: GO:0006412 - translation [Evidence IEA] AKAW2_11455A BUSCO:EOG09261RU1; COG:J; EggNog:ENOG410PG09; InterPro:IPR006195,IPR040725,IPR004529,IPR002319; PFAM:PF18553,PF01409; TransMembrane:1 (o396-416i); go_component: GO:0005737 - cytoplasm [Evidence IEA]; go_function: GO:0000049 - tRNA binding [Evidence IEA]; go_function: GO:0000166 - nucleotide binding [Evidence IEA]; go_function: GO:0004812 - aminoacyl-tRNA ligase activity [Evidence IEA]; go_function: GO:0004826 - phenylalanine-tRNA ligase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006432 - phenylalanyl-tRNA aminoacylation [Evidence IEA]; go_process: GO:0043039 - tRNA aminoacylation [Evidence IEA] AKAW2_11456S COG:T; EggNog:ENOG410PF99; InterPro:IPR001789,IPR003594,IPR003661,IPR003660, IPR036890,IPR036097,IPR011006,IPR004358,IPR005467; PFAM:PF00512,PF00672,PF02518,PF00072,PF18947; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0000155 - phosphorelay sensor kinase activity [Evidence IEA]; go_function: GO:0016772 - transferase activity, transferring phosphorus-containing groups [Evidence IEA]; go_process: GO:0000160 - phosphorelay signal transduction system [Evidence IEA]; go_process: GO:0007165 - signal transduction [Evidence IEA]; go_process: GO:0016310 - phosphorylation [Evidence IEA] AKAW2_11457A SECRETED:SignalP(1-23) AKAW2_11458A COG:G; EggNog:ENOG410QDB6; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i125-147o167-188i195-213o219-241i253-272o284-304i330- 352o364-383i395-414o420-443i455-473o485-506i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_11459A COG:S; EggNog:ENOG410PYH8 AKAW2_11461A COG:S; EggNog:ENOG410PMBG; InterPro:IPR007751,IPR029058; PFAM:PF05057 AKAW2_11464A COG:S; EggNog:ENOG410PQK6 AKAW2_11465S COG:O; EggNog:ENOG410PI6E AKAW2_11466S COG:O; EggNog:ENOG410PI6E; InterPro:IPR027417,IPR003593,IPR003959; PFAM:PF00004; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA] AKAW2_11467S COG:E,O; EggNog:ENOG410Q1SM; InterPro:IPR018202,IPR001563,IPR033124,IPR029058; MEROPS:MER0002512; PFAM:PF00450; SECRETED:SignalP(1-49); go_function: GO:0004185 - serine-type carboxypeptidase activity [Evidence IEA]; go_process: GO:0006508 - proteolysis [Evidence IEA] AKAW2_11468A TransMembrane:1 (i101-117o) AKAW2_11469A COG:S; EggNog:ENOG410PFJ9; InterPro:IPR037190,IPR036322,IPR017252,IPR015943, IPR001680,IPR019775,IPR020472,IPR006594,IPR017986; PFAM:PF12894,PF00400; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_11471S COG:G; EggNog:ENOG410Q1SR; InterPro:IPR020846,IPR005828,IPR036259; PFAM:PF07690,PF00083; TransMembrane:12 (i110-129o149-168i180-200o206-230i237-260o290-311i394- 415o435-457i469-486o492-514i526-550o556-577i); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_11472A COG:T; EggNog:ENOG410PGJ8; InterPro:IPR000719,IPR011009,IPR008271; PFAM:PF07714,PF00069; TransMembrane:1 (i318-336o); go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_11473S COG:S; EggNog:ENOG410PMAU AKAW2_11474A COG:K; EggNog:ENOG410PHJM; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_11476A COG:S; EggNog:ENOG410PGEV; InterPro:IPR015943,IPR001810,IPR036047; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_11477A BUSCO:EOG09262QRH; COG:U; EggNog:ENOG410PGG7; InterPro:IPR036412,IPR027111,IPR023214,IPR004274; PFAM:PF03031; TransMembrane:1 (i162-179o); go_component: GO:0005743 - mitochondrial inner membrane [Evidence IEA]; go_component: GO:0005744 - TIM23 mitochondrial import inner membrane translocase complex [Evidence IEA]; go_process: GO:0015031 - protein transport [Evidence IEA] AKAW2_11478S COG:S; EggNog:ENOG410PMYS; InterPro:IPR038883 AKAW2_11479A BUSCO:EOG09263QB7; COG:O; EggNog:ENOG410PHCZ; InterPro:IPR024969,IPR037518,IPR035299,IPR000555; MEROPS:MER0022005; PFAM:PF13012,PF14464,PF01398; go_function: GO:0005515 - protein binding [Evidence IEA]; go_function: GO:0008237 - metallopeptidase activity [Evidence IEA]; go_function: GO:0061578 - Lys63-specific deubiquitinase activity [Evidence IEA]; go_function: GO:0070122 - isopeptidase activity [Evidence IEA] AKAW2_11480S COG:B; EggNog:ENOG410PHUX; InterPro:IPR037138,IPR023696,IPR003084,IPR023801, IPR000286; PFAM:PF00850; go_function: GO:0004407 - histone deacetylase activity [Evidence IEA]; go_process: GO:0016575 - histone deacetylation [Evidence IEA] AKAW2_11481S BUSCO:EOG09265CQO; COG:J; EggNog:ENOG410PMYQ; InterPro:IPR000218,IPR019972,IPR036853; PFAM:PF00238; go_component: GO:0005840 - ribosome [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_process: GO:0006412 - translation [Evidence IEA] AKAW2_11482A COG:L; EggNog:ENOG410PHBP; InterPro:IPR033308,IPR033307; TransMembrane:1 (n6-16c21/22o521-540i); go_process: GO:0006506 - GPI anchor biosynthetic process [Evidence IEA] AKAW2_11483A COG:T; EggNog:ENOG410PIJE; InterPro:IPR001849,IPR036028,IPR001660,IPR001452, IPR035551,IPR013761; PFAM:PF07653,PF00018,PF07647,PF14604,PF00169; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_11484S COG:K; EggNog:ENOG410PNZG; InterPro:IPR004181,IPR013083; PFAM:PF02891; go_function: GO:0008270 - zinc ion binding [Evidence IEA] AKAW2_11485A COG:S; EggNog:ENOG410PFP8; InterPro:IPR031355; PFAM:PF17104 AKAW2_11486S COG:Y; EggNog:ENOG410PGJ5; InterPro:IPR007758,IPR025574,IPR026010; PFAM:PF13634,PF05064; go_component: GO:0005643 - nuclear pore [Evidence IEA]; go_function: GO:0017056 - structural constituent of nuclear pore [Evidence IEA] AKAW2_11487A COG:S; EggNog:ENOG410PSSD; InterPro:IPR007648; PFAM:PF04568; go_component: GO:0005739 - mitochondrion [Evidence IEA]; go_function: GO:0042030 - ATPase inhibitor activity [Evidence IEA]; go_process: GO:0032780 - negative regulation of ATPase activity [Evidence IEA] AKAW2_11488S COG:O; EggNog:ENOG410PHTI; InterPro:IPR023410,IPR000308,IPR036815,IPR023409; PFAM:PF00244 AKAW2_11489S TransMembrane:2 (n7-14c23/24o33-53i65-85o) AKAW2_11490A COG:S; EggNog:ENOG410PRKQ; InterPro:IPR019357; PFAM:PF10224 AKAW2_11491S SECRETED:SignalP(1-31) AKAW2_11492A CAZy:GH76; COG:G; EggNog:ENOG410PG4P; InterPro:IPR005198; SECRETED:SignalP(1-22) AKAW2_11493A COG:A; EggNog:ENOG410PPRS; InterPro:IPR000504,IPR008111,IPR035979,IPR012677, IPR033744; PFAM:PF00076; go_component: GO:0005634 - nucleus [Evidence IEA]; go_component: GO:0005737 - cytoplasm [Evidence IEA]; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0003723 - RNA binding [Evidence IEA]; go_function: GO:0003729 - mRNA binding [Evidence IEA]; go_process: GO:0006396 - RNA processing [Evidence IEA] AKAW2_11494S COG:S; EggNog:ENOG410Q1KP AKAW2_11495A COG:T; EggNog:ENOG410PHM7; InterPro:IPR006214; PFAM:PF01027; TransMembrane:7 (o77-95i116-134o146-166i178-196o202-222i229-255o267-284i) AKAW2_11496S COG:S; EggNog:ENOG410Q13K; InterPro:IPR013926,IPR036504; PFAM:PF08617 AKAW2_11497S COG:L; EggNog:ENOG410PPZT; InterPro:IPR018574,IPR027784; PFAM:PF09494; go_component: GO:0005634 - nucleus [Evidence IEA]; go_component: GO:0033557 - Slx1-Slx4 complex [Evidence IEA]; go_function: GO:0017108 - 5'-flap endonuclease activity [Evidence IEA]; go_process: GO:0006260 - DNA replication [Evidence IEA]; go_process: GO:0006281 - DNA repair [Evidence IEA] AKAW2_11498A InterPro:IPR036864,IPR001138; PFAM:PF00172; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_11499A COG:P,T; EggNog:ENOG410QE71; InterPro:IPR018488,IPR001810,IPR000595,IPR018490, IPR036047,IPR032675,IPR014710,IPR006553; PFAM:PF00027,PF00646,PF16643,PF12937; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_11500A COG:S; EggNog:ENOG410PRES AKAW2_11501S COG:S; EggNog:ENOG410PXXS AKAW2_11502S BUSCO:EOG09260BRA; COG:Z; EggNog:ENOG410PGBY; InterPro:IPR019821,IPR036961,IPR027417,IPR027640, IPR001752; PFAM:PF16796,PF00225; go_function: GO:0003777 - microtubule motor activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0008017 - microtubule binding [Evidence IEA]; go_process: GO:0007018 - microtubule-based movement [Evidence IEA] AKAW2_11503S COG:O; EggNog:ENOG410PI59; InterPro:IPR036509,IPR002569; PFAM:PF01625; go_function: GO:0008113 - peptide-methionine (S)-S-oxide reductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_11504A COG:S; EggNog:ENOG410PXXZ AKAW2_11505S CAZy:GH16; COG:G; EggNog:ENOG410PH2Y; InterPro:IPR000757,IPR013320,IPR017168; PFAM:PF00722; SECRETED:SignalP(1-20); TransMembrane:1 (n5-15c20/21o410-427i); go_component: GO:0005618 - cell wall [Evidence IEA]; go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_function: GO:0016798 - hydrolase activity, acting on glycosyl bonds [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA]; go_process: GO:0071555 - cell wall organization [Evidence IEA] AKAW2_11506A COG:P; EggNog:ENOG410PGCW; InterPro:IPR001952,IPR017850,IPR018299; PFAM:PF00245; TransMembrane:1 (i48-68o); go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0016791 - phosphatase activity [Evidence IEA] AKAW2_11507A COG:S; EggNog:ENOG410PNVB; InterPro:IPR007523,IPR034095,IPR036748; PFAM:PF04430; go_process: GO:0032981 - mitochondrial respiratory chain complex I assembly [Evidence IEA] AKAW2_11508A COG:Q; EggNog:ENOG410PH02; InterPro:IPR017871,IPR027417,IPR003593,IPR039421, IPR011527,IPR003439,IPR036640; PFAM:PF00005,PF00664; TransMembrane:10 (o12-36i81-106o118-137i149-169o198-217i301-318o338- 356i423-442o448-468i540-558o); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA]; go_function: GO:0042626 - ATPase-coupled transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_11509S COG:U; EggNog:ENOG410PHM3; InterPro:IPR036322,IPR015943,IPR001680,IPR019775, IPR020472,IPR037590,IPR017986; PFAM:PF00400; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0032008 - positive regulation of TOR signaling [Evidence IEA] AKAW2_11510A COG:S; EggNog:ENOG410PQ86; InterPro:IPR015381; PFAM:PF09302; go_component: GO:0005634 - nucleus [Evidence IEA]; go_process: GO:0006302 - double-strand break repair [Evidence IEA] AKAW2_11511S COG:T; EggNog:ENOG410PFCZ; InterPro:IPR018816,IPR019134; PFAM:PF10312,PF09732; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_11512S COG:K; EggNog:ENOG410PRNW; InterPro:IPR030456,IPR001766,IPR036390,IPR036388; PFAM:PF00250; go_function: GO:0003700 - DNA-binding transcription factor activity [Evidence IEA]; go_function: GO:0043565 - sequence-specific DNA binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_11514A COG:J; EggNog:ENOG410PPQN; InterPro:IPR018065,IPR038562,IPR008195; PFAM:PF01199; go_component: GO:0005840 - ribosome [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_process: GO:0006412 - translation [Evidence IEA] AKAW2_11515S BUSCO:EOG092600NM; COG:A; EggNog:ENOG410PHSR; InterPro:IPR012337,IPR037518,IPR043173,IPR043172, IPR027652,IPR019582,IPR012984,IPR019580,IPR012591, IPR019581,IPR042516,IPR012592,IPR021983,IPR000555; PFAM:PF08083,PF10598,PF10596,PF12134,PF08084, PF10597,PF08082; go_component: GO:0005681 - spliceosomal complex [Evidence IEA]; go_function: GO:0003723 - RNA binding [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_function: GO:0008237 - metallopeptidase activity [Evidence IEA]; go_function: GO:0017070 - U6 snRNA binding [Evidence IEA]; go_function: GO:0030623 - U5 snRNA binding [Evidence IEA]; go_function: GO:0070122 - isopeptidase activity [Evidence IEA]; go_process: GO:0000398 - mRNA splicing, via spliceosome [Evidence IEA] AKAW2_11516S TransMembrane:3 (i98-121o133-150i162-182o) AKAW2_11517S COG:K; EggNog:ENOG410PNVK; InterPro:IPR001005,IPR009057,IPR017930,IPR017877; PFAM:PF13921 AKAW2_11518S BUSCO:EOG09265MAN; COG:C; EggNog:ENOG410PR50; InterPro:IPR002124,IPR036972; PFAM:PF01215; go_component: GO:0005740 - mitochondrial envelope [Evidence IEA]; go_function: GO:0004129 - cytochrome-c oxidase activity [Evidence IEA] AKAW2_11519A COG:P; EggNog:ENOG410PG6R; InterPro:IPR001248,IPR030175,IPR026030,IPR038271; PFAM:PF02133; TransMembrane:12 (i84-103o115-142i163-182o202-223i230-248o268-290i302- 327o354-374i395-413o419-439i464-487o499-519i); go_component: GO:0005886 - plasma membrane [Evidence IEA]; go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_function: GO:0031924 - vitamin B6 transmembrane transporter activity [Evidence IEA]; go_process: GO:0031919 - vitamin B6 transport [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_11520A COG:K; EggNog:ENOG410PPD8; InterPro:IPR017930,IPR009057,IPR017877,IPR001005; PFAM:PF00249,PF13921 AKAW2_11522S COG:U; EggNog:ENOG410PK6I; InterPro:IPR000133; PFAM:PF00810; TransMembrane:7 (o6-27i34-52o64-84i96-120o132-150i162-180o192-212i); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0046923 - ER retention sequence binding [Evidence IEA]; go_process: GO:0006621 - protein retention in ER lumen [Evidence IEA] AKAW2_11524S COG:S; EggNog:ENOG410PYYX AKAW2_11525A BUSCO:EOG09262NB1; COG:J; EggNog:ENOG410PFZ1; InterPro:IPR029064,IPR005142,IPR004405,IPR005140, IPR005141,IPR042226,IPR038069; PFAM:PF03464,PF03463,PF03465; go_process: GO:0070481 - nuclear-transcribed mRNA catabolic process, non-stop decay [Evidence IEA]; go_process: GO:0070966 - nuclear-transcribed mRNA catabolic process, no-go decay [Evidence IEA]; go_process: GO:0071025 - RNA surveillance [Evidence IEA] AKAW2_11526S COG:S; EggNog:ENOG410PJMQ; InterPro:IPR018170,IPR020471,IPR036812,IPR023210; PFAM:PF00248; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_11527S COG:S; EggNog:ENOG410PN8P AKAW2_11528S COG:S; EggNog:ENOG410PN8P; InterPro:IPR022742,IPR029058; MEROPS:MER0037236; PFAM:PF12697,PF12146 AKAW2_11529A COG:E; EggNog:ENOG410PKGR; InterPro:IPR015889,IPR007535,IPR039390,IPR000627; PFAM:PF04444,PF00775; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0008199 - ferric iron binding [Evidence IEA]; go_function: GO:0016702 - oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [Evidence IEA]; go_function: GO:0018576 - catechol 1,2-dioxygenase activity [Evidence IEA]; go_process: GO:0006725 - cellular aromatic compound metabolic process [Evidence IEA]; go_process: GO:0009712 - catechol-containing compound metabolic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_11530A COG:J; EggNog:ENOG410PPA7; InterPro:IPR002745,IPR042080; PFAM:PF01885; go_function: GO:0003950 - NAD+ ADP-ribosyltransferase activity [Evidence IEA] AKAW2_11531A COG:S; EggNog:ENOG410PGNQ; InterPro:IPR036322,IPR015943,IPR031488,IPR001680, IPR037593; PFAM:PF17034; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_11532S BUSCO:EOG09264UKL; COG:S; EggNog:ENOG410PSH4; InterPro:IPR019310; PFAM:PF10153; go_process: GO:0006364 - rRNA processing [Evidence IEA] AKAW2_11533A COG:S; EggNog:ENOG410PJ93; InterPro:IPR001611,IPR001810,IPR006553,IPR036047, IPR032675; PFAM:PF13516,PF00646,PF12937; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_11536A COG:T; EggNog:ENOG410QD8C; InterPro:IPR000719,IPR011009,IPR008271; PFAM:PF07714,PF00069; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_11537A COG:U; EggNog:ENOG410PH7C; InterPro:IPR035969,IPR000195; PFAM:PF00566 AKAW2_11538S COG:S; EggNog:ENOG410PP4A AKAW2_11539S COG:S; EggNog:ENOG410PPS5; InterPro:IPR034751,IPR004910,IPR039058; PFAM:PF03226 AKAW2_11540S COG:Q; EggNog:ENOG410PG9N; InterPro:IPR013154,IPR013149,IPR002328,IPR036291, IPR011032,IPR020843; PFAM:PF00107,PF08240; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_11541S COG:A; EggNog:ENOG410PK1N; InterPro:IPR004087,IPR004088,IPR036612; PFAM:PF00013; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0003723 - RNA binding [Evidence IEA] AKAW2_11542A COG:S; EggNog:ENOG410PM53 AKAW2_11543S COG:V; EggNog:ENOG410PMWH; InterPro:IPR020422,IPR029021,IPR016130,IPR000387, IPR000340; PFAM:PF00782; go_function: GO:0004725 - protein tyrosine phosphatase activity [Evidence IEA]; go_function: GO:0008138 - protein tyrosine/serine/threonine phosphatase activity [Evidence IEA]; go_function: GO:0016791 - phosphatase activity [Evidence IEA]; go_process: GO:0006470 - protein dephosphorylation [Evidence IEA]; go_process: GO:0016311 - dephosphorylation [Evidence IEA] AKAW2_11544S COG:S; EggNog:ENOG410PMV7; InterPro:IPR026635,IPR029063,IPR025714; go_function: GO:0008168 - methyltransferase activity [Evidence IEA] AKAW2_11545A COG:S; EggNog:ENOG410QE1C; InterPro:IPR029063,IPR019410; PFAM:PF10294 AKAW2_11546S COG:S; EggNog:ENOG410PHSP; InterPro:IPR013087 AKAW2_11547A COG:K; EggNog:ENOG410PGYQ; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; TransMembrane:2 (o614-633i645-666o); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_11548A COG:O; EggNog:ENOG410PQPJ; InterPro:IPR001623,IPR036869 AKAW2_11549S COG:J; EggNog:ENOG410PH0Y; InterPro:IPR038630,IPR000988 AKAW2_11550S COG:O; EggNog:ENOG410PHG7; InterPro:IPR000642,IPR041569,IPR003959,IPR027417, IPR003593,IPR003960,IPR037219,IPR011546,IPR005936; MEROPS:MER0002600; PFAM:PF00004,PF01434,PF06480,PF17862; TransMembrane:2 (i234-254o356-376i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0004176 - ATP-dependent peptidase activity [Evidence IEA]; go_function: GO:0004222 - metalloendopeptidase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA]; go_process: GO:0006508 - proteolysis [Evidence IEA] AKAW2_11551A COG:S; EggNog:ENOG410PH50; InterPro:IPR010721; PFAM:PF06966; TransMembrane:5 (o57-75i87-105o111-129i157-179o199-218i) AKAW2_11552S BUSCO:EOG09260XL0; COG:L; EggNog:ENOG410PJ78; InterPro:IPR034144,IPR006171,IPR003602,IPR003601, IPR013826,IPR013824,IPR013825,IPR023406,IPR013497, IPR000380,IPR023405; PFAM:PF01131,PF01751; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0003916 - DNA topoisomerase activity [Evidence IEA]; go_function: GO:0003917 - DNA topoisomerase type I (single strand cut, ATP-independent) activity [Evidence IEA]; go_process: GO:0006265 - DNA topological change [Evidence IEA] AKAW2_11553S TransMembrane:1 (i88-110o) AKAW2_11554S COG:S; EggNog:ENOG410Q078 AKAW2_11555A COG:S; EggNog:ENOG410PTG5; SECRETED:SignalP(1-20) AKAW2_11556S COG:S; EggNog:ENOG410PTTE AKAW2_11557A COG:S; EggNog:ENOG410PXXD AKAW2_11558S COG:A; EggNog:ENOG410PVDN; InterPro:IPR037783,IPR036322,IPR027417,IPR007111, IPR015943,IPR019775,IPR001680,IPR031359,IPR017986; PFAM:PF05729,PF00400,PF17100; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_11559A COG:C; EggNog:ENOG410PJBY; InterPro:IPR005828,IPR003663,IPR036259,IPR020846; PFAM:PF00083,PF07690; SMCOG1169:sugar transport protein; TransMembrane:11 (i19-36o74-97i135-152o164-186i198-219o306-326i338-355o361- 383i395-418o438-459i466-485o); antiSMASH:Cluster_1.17; go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_11560A antiSMASH:Cluster_1.17 AKAW2_11561S COG:C; EggNog:ENOG410PGM9; InterPro:IPR036188,IPR006258,IPR004099,IPR023753, IPR016156; PFAM:PF02852,PF00070; SMCOG1175:pyridine nucleotide-disulfide oxidoreductase; antiSMASH:Cluster_1.17; go_function: GO:0004148 - dihydrolipoyl dehydrogenase activity [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_process: GO:0045454 - cell redox homeostasis [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_11562A COG:Q; EggNog:ENOG410PPEB; InterPro:IPR036291,IPR002347; PFAM:PF08659,PF00106,PF13561; SMCOG1001:short-chain dehydrogenase/reductase SDR; antiSMASH:Cluster_1.17; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_11563A COG:G; EggNog:ENOG410PIBT; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; SMCOG1005:Drug resistance transporter, EmrB/QacA; TransMembrane:14 (i28-46o68-86i98-117o123-144i156-178o190-208i220-248o260- 284i305-325o337-357i369-387o399-420i432-455o509-527i); antiSMASH:Cluster_1.17; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_11564A COG:S; EggNog:ENOG410Q2TY; TransMembrane:6 (i19-36o56-73i134-156o178-202i214-235o255-278i); antiSMASH:Cluster_1.17 AKAW2_11565A COG:E; EggNog:ENOG410Q0GJ; InterPro:IPR005645,IPR029058; PFAM:PF03959; antiSMASH:Cluster_1.17 AKAW2_11566S COG:I; EggNog:ENOG410PJWX; InterPro:IPR016036,IPR016035,IPR016039,IPR018201, IPR042104,IPR014030,IPR011032,IPR013968,IPR001227, IPR032821,IPR014031,IPR006162,IPR014043,IPR020806, IPR020807,IPR020843,IPR020841,IPR009081,IPR029063, IPR036736,IPR036291,IPR013217; PFAM:PF16197,PF00109,PF10294,PF13489,PF13649, PF01209,PF02801,PF00698,PF13847,PF08659,PF14765,PF00106, PF08242,PF08241; SMCOG1022:Beta-ketoacyl synthase; antiSMASH:Cluster_1.17; go_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein] synthase activity [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0016740 - transferase activity [Evidence IEA]; go_function: GO:0016746 - transferase activity, transferring acyl groups [Evidence IEA]; go_function: GO:0031177 - phosphopantetheine binding [Evidence IEA]; go_process: GO:0006633 - fatty acid biosynthetic process [Evidence IEA] AKAW2_11567A COG:S; EggNog:ENOG410PTR2; InterPro:IPR029032,IPR003779; PFAM:PF02627; SMCOG1298:putative carboxymuconolactone decarboxylase; TransMembrane:1 (o15-32i); antiSMASH:Cluster_1.17; go_function: GO:0051920 - peroxiredoxin activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_11568S COG:C,H; EggNog:ENOG410QEF6; InterPro:IPR036188; SMCOG1087:hypothetical protein; antiSMASH:Cluster_1.17 AKAW2_11569A COG:G; EggNog:ENOG410PGSN; InterPro:IPR036900,IPR016055,IPR005846,IPR005845, IPR005844,IPR005843,IPR005841,IPR016066; PFAM:PF02879,PF02878,PF02880; antiSMASH:Cluster_1.17; go_function: GO:0000287 - magnesium ion binding [Evidence IEA]; go_function: GO:0016868 - intramolecular transferase activity, phosphotransferases [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA]; go_process: GO:0071704 - organic substance metabolic process [Evidence IEA] AKAW2_11570S COG:I; EggNog:ENOG410PFMX; InterPro:IPR001199,IPR012171,IPR005804,IPR036400; PFAM:PF00173,PF00487; TransMembrane:4 (i235-256o276-294i354-371o391-410i); antiSMASH:Cluster_1.17; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0006629 - lipid metabolic process [Evidence IEA] AKAW2_11571S BUSCO:EOG09265CFP; COG:J; EggNog:ENOG410PQ4U; InterPro:IPR036838,IPR001848,IPR018268,IPR005729, IPR027486; PFAM:PF00338; antiSMASH:Cluster_1.17; go_component: GO:0005840 - ribosome [Evidence IEA]; go_component: GO:0015935 - small ribosomal subunit [Evidence IEA]; go_function: GO:0003723 - RNA binding [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_process: GO:0006412 - translation [Evidence IEA] AKAW2_11572A COG:S; EggNog:ENOG410PM7N; InterPro:IPR036855,IPR000571,IPR041367; PFAM:PF18044,PF00642; antiSMASH:Cluster_1.17; go_function: GO:0046872 - metal ion binding [Evidence IEA] AKAW2_11573A COG:S; EggNog:ENOG410PSEP; InterPro:IPR025151; PFAM:PF13934; antiSMASH:Cluster_1.17 AKAW2_11574S COG:D; EggNog:ENOG410PFHT; InterPro:IPR010935,IPR003395,IPR041738,IPR027417, IPR036277; PFAM:PF06470,PF02463; antiSMASH:Cluster_1.17; go_component: GO:0005694 - chromosome [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0051276 - chromosome organization [Evidence IEA] AKAW2_11575S COG:S; EggNog:ENOG410PN28 AKAW2_11577S COG:E,U; EggNog:ENOG410PIH7; InterPro:IPR037521,IPR037520,IPR021713; PFAM:PF11704 AKAW2_11578A BUSCO:EOG09261DRB; COG:S; EggNog:ENOG410PKBG; InterPro:IPR032319,IPR027417; PFAM:PF16575 AKAW2_11579S COG:S; EggNog:ENOG410PSVB; InterPro:IPR013240; PFAM:PF08208; go_process: GO:0006360 - transcription by RNA polymerase I [Evidence IEA] AKAW2_11580S CAZy:GT1; COG:I; EggNog:ENOG410PGF0; InterPro:IPR011993,IPR004276,IPR001849,IPR004182; PFAM:PF00169,PF03033; go_function: GO:0016758 - transferase activity, transferring hexosyl groups [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA]; go_process: GO:0030259 - lipid glycosylation [Evidence IEA] AKAW2_11581A BUSCO:EOG09264UVA; COG:O; EggNog:ENOG410PMX5; InterPro:IPR004127,IPR016655,IPR009053; PFAM:PF02996; go_component: GO:0016272 - prefoldin complex [Evidence IEA]; go_process: GO:0006457 - protein folding [Evidence IEA] AKAW2_11582S COG:S; EggNog:ENOG410PN7C; InterPro:IPR021013; PFAM:PF11712; TransMembrane:2 (i166-185o217-238i); go_process: GO:0070072 - vacuolar proton-transporting V-type ATPase complex assembly [Evidence IEA] AKAW2_11583A COG:S; EggNog:ENOG410PNF1 AKAW2_11584A BUSCO:EOG09265D7J; COG:J; EggNog:ENOG410PP96; InterPro:IPR001209,IPR043140; PFAM:PF00253; go_component: GO:0005840 - ribosome [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_process: GO:0006412 - translation [Evidence IEA] AKAW2_11585A COG:C; EggNog:ENOG410PS1N; InterPro:IPR006995; PFAM:PF04911; TransMembrane:1 (o20-38i); go_component: GO:0045263 - proton-transporting ATP synthase complex, coupling factor F(o) [Evidence IEA]; go_function: GO:0015078 - proton transmembrane transporter activity [Evidence IEA]; go_process: GO:0015986 - ATP synthesis coupled proton transport [Evidence IEA] AKAW2_11587S COG:S; EggNog:ENOG410PPMH; InterPro:IPR013251; PFAM:PF08287; go_component: GO:0005876 - spindle microtubule [Evidence IEA]; go_component: GO:0042729 - DASH complex [Evidence IEA]; go_process: GO:0008608 - attachment of spindle microtubules to kinetochore [Evidence IEA] AKAW2_11586A COG:J; EggNog:ENOG410PH29; InterPro:IPR015324; go_function: GO:0008168 - methyltransferase activity [Evidence IEA]; go_process: GO:0006412 - translation [Evidence IEA] AKAW2_11588A COG:S; EggNog:ENOG410PQJK; InterPro:IPR028241; PFAM:PF10259 AKAW2_11589S COG:S; EggNog:ENOG410PP30; InterPro:IPR009571; PFAM:PF06687; TransMembrane:3 (n10-28c33/34o114-136i148-169o189-212i); go_component: GO:0005886 - plasma membrane [Evidence IEA] AKAW2_11590A COG:O; EggNog:ENOG410PHA3; InterPro:IPR013126,IPR043129; PFAM:PF00012 AKAW2_11591S BUSCO:EOG09264XJC; COG:J; EggNog:ENOG410PKPF; InterPro:IPR041054,IPR036612,IPR012340,IPR026699, IPR004088; PFAM:PF15985,PF18311; go_component: GO:0000178 - exosome (RNase complex) [Evidence IEA]; go_function: GO:0003723 - RNA binding [Evidence IEA] AKAW2_11592S CAZy:AA3; COG:E; EggNog:ENOG410PFGF; InterPro:IPR007867,IPR012132,IPR036188; PFAM:PF05199; go_function: GO:0016614 - oxidoreductase activity, acting on CH-OH group of donors [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_11593A COG:J; EggNog:ENOG410PPR2; InterPro:IPR006175,IPR035959; PFAM:PF01042 AKAW2_11594S COG:K; EggNog:ENOG410PMZT; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF04082; TransMembrane:1 (o467-486i); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_11595A COG:Q; EggNog:ENOG410PGFN; InterPro:IPR011032,IPR013154,IPR036291; PFAM:PF08240; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_11596S CAZy:GH3; COG:G; EggNog:ENOG410PFI5; InterPro:IPR017853,IPR036962,IPR037524,IPR008979, IPR002772,IPR036881,IPR026891,IPR013783,IPR001764, IPR011658; PFAM:PF00933,PF01915,PF14310,PF07691; go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_11597S COG:A; EggNog:ENOG410PFSV; InterPro:IPR005829,IPR005828,IPR003663,IPR036259, IPR020846; PFAM:PF00083,PF07690; TransMembrane:12 (i7-27o56-77i84-103o109-132i144-164o176-195i263-283o295- 318i325-344o356-379i391-411o423-446i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_11598S InterPro:IPR020846,IPR005828,IPR036259; TransMembrane:3 (i45-71o97-118i125-144o); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_11599S COG:G; EggNog:ENOG410PF97; InterPro:IPR005829,IPR005828,IPR036259,IPR020846; PFAM:PF00083,PF07690; TransMembrane:8 (i49-69o89-111i171-192o204-226i235-254o266-289i301- 324o336-354i); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_11600S COG:T; EggNog:ENOG410PW8S; InterPro:IPR000719,IPR011009; PFAM:PF00069; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_11601S COG:Q; EggNog:ENOG410PWEY; InterPro:IPR001128,IPR036396; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_11602A COG:O; EggNog:ENOG410PZYJ AKAW2_11603A COG:G; EggNog:ENOG410PUTR; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690,PF00083; TransMembrane:12 (i81-102o122-141i148-167o173-195i207-229o235-257i319- 338o358-379i400-420o426-447i459-482o494-516i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_11604A BUSCO:EOG0926049A; CAZy:GT24; COG:O; EggNog:ENOG410PHC3; InterPro:IPR040497,IPR029044,IPR040525,IPR009448, IPR040693,IPR040692,IPR040694; PFAM:PF18403,PF18402,PF18404,PF18400,PF18401, PF06427; SECRETED:SignalP(1-28); go_function: GO:0003980 - UDP-glucose:glycoprotein glucosyltransferase activity [Evidence IEA]; go_process: GO:0006486 - protein glycosylation [Evidence IEA] AKAW2_11605A COG:S; EggNog:ENOG410PMBE AKAW2_11606S COG:Q; EggNog:ENOG410PVQY; InterPro:IPR015798,IPR016182,IPR036460,IPR000269, IPR015802; PFAM:PF01179,PF02728; go_function: GO:0005507 - copper ion binding [Evidence IEA]; go_function: GO:0008131 - primary amine oxidase activity [Evidence IEA]; go_function: GO:0048038 - quinone binding [Evidence IEA]; go_process: GO:0009308 - amine metabolic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_11607S COG:S; EggNog:ENOG410Q19Q AKAW2_11608S COG:S; EggNog:ENOG410PT02; InterPro:IPR010730; PFAM:PF06985 AKAW2_11609S COG:S; EggNog:ENOG410PXZA AKAW2_11611S COG:A; EggNog:ENOG410PSIW; InterPro:IPR020241,IPR014612,IPR036882; PFAM:PF01918,PF12328; go_component: GO:0005634 - nucleus [Evidence IEA]; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0004526 - ribonuclease P activity [Evidence IEA]; go_process: GO:0008033 - tRNA processing [Evidence IEA] AKAW2_11610A COG:K; EggNog:ENOG410Q1NG; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172; TransMembrane:1 (o272-293i); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_11612A COG:T; EggNog:ENOG410PJ97; InterPro:IPR008984,IPR000253; PFAM:PF00498; TransMembrane:1 (o738-755i); go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_11613S BUSCO:EOG09265KNL; COG:S; EggNog:ENOG410PRBY; InterPro:IPR018450; PFAM:PF10247; TransMembrane:2 (i28-47o59-77i) AKAW2_11614A COG:S; EggNog:ENOG410PN3F; InterPro:IPR010699; PFAM:PF06912; TransMembrane:6 (i43-63o69-87i99-119o125-145i225-242o248-269i) AKAW2_11615A CAZy:AA3; COG:E; EggNog:ENOG410PHJ8; InterPro:IPR012132,IPR036188,IPR000172,IPR007867; PFAM:PF05199,PF00732; go_function: GO:0016614 - oxidoreductase activity, acting on CH-OH group of donors [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_11616A COG:G; EggNog:ENOG410Q1Z0; InterPro:IPR005829,IPR005828,IPR003663,IPR036259, IPR020846; PFAM:PF00083,PF07690; TransMembrane:11 (n18-26c44/45o68-88i95-115o127-145i157-178o190-211i284- 302o322-346i353-374o386-409i421-439o464-482i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_11617A COG:O; EggNog:ENOG410Q2TW; InterPro:IPR036249,IPR040079,IPR036282,IPR010987, IPR004045,IPR004046; PFAM:PF13409,PF14497,PF13417,PF02798; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0006749 - glutathione metabolic process [Evidence IEA] AKAW2_11618S COG:S; EggNog:ENOG410PMB2 AKAW2_11619S COG:G; EggNog:ENOG410QE3G; InterPro:IPR036259,IPR010573; PFAM:PF07690; TransMembrane:14 (i53-70o90-110i122-143o149-166i178-197o209-231i256- 284o296-316i328-348o368-391i400-418o424-451i463-485o539- 556i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_11620S SECRETED:SignalP(1-21) AKAW2_11621S COG:S; EggNog:ENOG410PN08; InterPro:IPR001611,IPR003591,IPR032675; PFAM:PF13855; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_11622A COG:O; EggNog:ENOG410PGTS; InterPro:IPR001841,IPR003137,IPR013083; PFAM:PF17123,PF02225,PF13923,PF13639,PF14634, PF00097,PF13445,PF12678; TransMembrane:1 (n6-16c21/22o607-627i) AKAW2_11624S COG:S; EggNog:ENOG410PZ41 AKAW2_11625S COG:S; EggNog:ENOG410PJRM; PFAM:PF07264; TransMembrane:4 (i55-73o85-107i166-189o236-257i) AKAW2_11626A BUSCO:EOG092609RF; COG:D; EggNog:ENOG410PGI1; InterPro:IPR016024,IPR011989,IPR029347,IPR036322, IPR019775,IPR015943,IPR004083,IPR001680,IPR017986; PFAM:PF14538; go_component: GO:0031931 - TORC1 complex [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0031929 - TOR signaling [Evidence IEA] AKAW2_11627S COG:S; EggNog:ENOG410PIAP; InterPro:IPR006652,IPR015915; PFAM:PF13415; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_11628A COG:T; EggNog:ENOG410PFS3; InterPro:IPR017441,IPR008271,IPR030509,IPR000719, IPR011009; PFAM:PF07714,PF00069; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_11629A COG:K; EggNog:ENOG410PMSR; InterPro:IPR004827; PFAM:PF00170; go_function: GO:0003700 - DNA-binding transcription factor activity [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_11630A BUSCO:EOG09264873; COG:T; EggNog:ENOG410PFC1; InterPro:IPR036249,IPR024253; PFAM:PF02114 AKAW2_11632S BUSCO:EOG09260JTZ; COG:U; EggNog:ENOG410PIB8; InterPro:IPR016024,IPR011989,IPR032154,IPR012295, IPR013040,IPR013041,IPR002553,IPR037067,IPR009028, IPR017106; PFAM:PF01602,PF08752,PF13646,PF16381; go_component: GO:0030117 - membrane coat [Evidence IEA]; go_component: GO:0030126 - COPI vesicle coat [Evidence IEA]; go_function: GO:0005198 - structural molecule activity [Evidence IEA]; go_process: GO:0006886 - intracellular protein transport [Evidence IEA]; go_process: GO:0016192 - vesicle-mediated transport [Evidence IEA] AKAW2_11633A COG:S; EggNog:ENOG410PIJ8; InterPro:IPR001810,IPR032675; PFAM:PF12937; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_11634S COG:I; EggNog:ENOG410PHQT; InterPro:IPR036412,IPR006357,IPR006353,IPR023214; PFAM:PF13242,PF13344 AKAW2_11635S COG:J; EggNog:ENOG410PFAW; InterPro:IPR006195,IPR002312,IPR012340,IPR004364, IPR004523; PFAM:PF00152; go_component: GO:0005737 - cytoplasm [Evidence IEA]; go_function: GO:0000166 - nucleotide binding [Evidence IEA]; go_function: GO:0004812 - aminoacyl-tRNA ligase activity [Evidence IEA]; go_function: GO:0004815 - aspartate-tRNA ligase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006418 - tRNA aminoacylation for protein translation [Evidence IEA]; go_process: GO:0006422 - aspartyl-tRNA aminoacylation [Evidence IEA] AKAW2_11636S COG:S; EggNog:ENOG410PH4E; InterPro:IPR035426; PFAM:PF04938 AKAW2_11637S COG:U; EggNog:ENOG410PFW0; InterPro:IPR000727,IPR001683,IPR036871; PFAM:PF00787; go_function: GO:0035091 - phosphatidylinositol binding [Evidence IEA] AKAW2_11638A BUSCO:EOG09261ACJ; COG:L; EggNog:ENOG410PK4Q; InterPro:IPR006164,IPR014893,IPR036494,IPR016194, IPR036465,IPR005161,IPR024193,IPR002035; PFAM:PF03731,PF02735,PF08785; go_component: GO:0005634 - nucleus [Evidence IEA]; go_component: GO:0043564 - Ku70:Ku80 complex [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0003684 - damaged DNA binding [Evidence IEA]; go_function: GO:0042162 - telomeric DNA binding [Evidence IEA]; go_process: GO:0000723 - telomere maintenance [Evidence IEA]; go_process: GO:0006303 - double-strand break repair via nonhomologous end joining [Evidence IEA]; go_process: GO:0006310 - DNA recombination [Evidence IEA] AKAW2_11639A COG:M; EggNog:ENOG410Q2I7; InterPro:IPR002110,IPR020683,IPR036770; PFAM:PF13637; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_11640S COG:C; EggNog:ENOG410PW3S; InterPro:IPR018108,IPR023395; PFAM:PF00153; TransMembrane:3 (i159-180o205-225i279-299o) AKAW2_11641A COG:S; EggNog:ENOG410Q024; InterPro:IPR036875,IPR001878; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA] AKAW2_11642A COG:M; EggNog:ENOG410Q2I7; InterPro:IPR002110,IPR020683,IPR036770; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_11643A COG:M; EggNog:ENOG410Q2I7 AKAW2_11644A COG:L; EggNog:ENOG410PREP; InterPro:IPR014048,IPR001497,IPR036388,IPR036217; PFAM:PF01035; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0003908 - methylated-DNA-[protein]-cysteine S-methyltransferase activity [Evidence IEA]; go_process: GO:0006281 - DNA repair [Evidence IEA] AKAW2_11645A COG:S; EggNog:ENOG410PTEP; InterPro:IPR036236,IPR013087; PFAM:PF00096 AKAW2_11646A COG:K; EggNog:ENOG410PIR5; InterPro:IPR012270,IPR007207,IPR007282,IPR040168, IPR038635; PFAM:PF04065,PF04153; go_component: GO:0005634 - nucleus [Evidence IEA]; go_component: GO:0030015 - CCR4-NOT core complex [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_11647S BUSCO:EOG09264ZQC; COG:J; EggNog:ENOG410PPBZ; InterPro:IPR003732,IPR023509; PFAM:PF02580; go_component: GO:0005737 - cytoplasm [Evidence IEA]; go_function: GO:0002161 - aminoacyl-tRNA editing activity [Evidence IEA]; go_function: GO:0051499 - D-aminoacyl-tRNA deacylase activity [Evidence IEA] AKAW2_11648A COG:O; EggNog:ENOG410PHJ3; InterPro:IPR011990,IPR002130,IPR013105,IPR020892, IPR019734,IPR013026,IPR029000; PFAM:PF07719,PF00160; go_function: GO:0003755 - peptidyl-prolyl cis-trans isomerase activity [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0000413 - protein peptidyl-prolyl isomerization [Evidence IEA]; go_process: GO:0006457 - protein folding [Evidence IEA] AKAW2_11649A COG:S; EggNog:ENOG410PRVV AKAW2_11650A COG:E; EggNog:ENOG410PH30; InterPro:IPR006076,IPR036188; PFAM:PF01266,PF00890; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_11651S COG:G; EggNog:ENOG410PMPF; InterPro:IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i57-73o100-117i124-143o149-172i184-205o211-233i322- 348o368-397i409-428o434-460i472-492o504-525i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_11652A COG:S; EggNog:ENOG410PYY2; InterPro:IPR037401,IPR032710; PFAM:PF12680 AKAW2_11653S COG:U; EggNog:ENOG410QDYG; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i49-72o92-109i116-133o145-168i175-193o205-225i310- 335o355-378i399-420o426-451i463-481o493-514i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_11654A COG:C; EggNog:ENOG410PKCF; InterPro:IPR004304; PFAM:PF03069; go_function: GO:0016811 - hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [Evidence IEA] AKAW2_11655A COG:S; EggNog:ENOG410PIEN; TransMembrane:5 (i39-67o87-106i179-198o218-239i273-298o) AKAW2_11656S COG:S; EggNog:ENOG410PQID; InterPro:IPR024758; PFAM:PF12634; TransMembrane:1 (o481-500i); go_component: GO:0005780 - extrinsic component of intraperoxisomal membrane [Evidence IEA]; go_process: GO:0045033 - peroxisome inheritance [Evidence IEA] AKAW2_11657A COG:U; EggNog:ENOG410PR8H; InterPro:IPR009018,IPR003210; PFAM:PF02290; go_component: GO:0005786 - signal recognition particle, endoplasmic reticulum targeting [Evidence IEA]; go_component: GO:0048500 - signal recognition particle [Evidence IEA]; go_function: GO:0008312 - 7S RNA binding [Evidence IEA]; go_function: GO:0030942 - endoplasmic reticulum signal peptide binding [Evidence IEA]; go_process: GO:0006614 - SRP-dependent cotranslational protein targeting to membrane [Evidence IEA] AKAW2_11658S BUSCO:EOG09261I1G; COG:T; EggNog:ENOG410PFVN; InterPro:IPR016024,IPR016021,IPR003890,IPR003891; PFAM:PF02854,PF02847; go_function: GO:0003723 - RNA binding [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_11659A COG:S; EggNog:ENOG410PYXU AKAW2_11660A COG:S; EggNog:ENOG410Q2TC AKAW2_11661A COG:S; EggNog:ENOG410PMWN; InterPro:IPR036412,IPR023214 AKAW2_11662A COG:G; EggNog:ENOG410QDAS; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i47-68o88-110i117-133o139-162i174-194o206-230i250- 272o284-302i314-335o341-364i376-396o408-429i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_11663S COG:S; EggNog:ENOG410PFB9; InterPro:IPR000073,IPR029058; MEROPS:MER0031610; PFAM:PF12697,PF00561 AKAW2_11664S COG:T; EggNog:ENOG410PUCU; InterPro:IPR000719,IPR011009,IPR017441; PFAM:PF00069; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_11665A COG:S; EggNog:ENOG410PQ0Z AKAW2_11666A COG:S; EggNog:ENOG410PQ0Z; InterPro:IPR011009,IPR002575; PFAM:PF01636 AKAW2_11667S COG:S; EggNog:ENOG410PMZJ; InterPro:IPR038921; SECRETED:SignalP(1-22); TransMembrane:1 (n6-17c22/23o518-537i) AKAW2_11668S COG:S; EggNog:ENOG410Q28S; SECRETED:SignalP(1-25) AKAW2_11669S COG:I; EggNog:ENOG410PH9Z; InterPro:IPR036188,IPR002938; go_function: GO:0071949 - FAD binding [Evidence IEA] AKAW2_11670S COG:K; EggNog:ENOG410Q2XA; InterPro:IPR036864,IPR001138; PFAM:PF00172; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_11672A COG:D; EggNog:ENOG410PM0Z; InterPro:IPR018564,IPR024146; PFAM:PF09444 AKAW2_11673A BUSCO:EOG09264XOZ; COG:K; EggNog:ENOG410Q10W; InterPro:IPR004343,IPR036128; PFAM:PF03126; go_function: GO:0003677 - DNA binding [Evidence IEA] AKAW2_11674S COG:H; EggNog:ENOG410PIYJ; InterPro:IPR009078,IPR011566; PFAM:PF03232; go_function: GO:0004497 - monooxygenase activity [Evidence IEA]; go_process: GO:0006744 - ubiquinone biosynthetic process [Evidence IEA] AKAW2_11675A BUSCO:EOG09265A08; COG:T; EggNog:ENOG410PN7B; InterPro:IPR023485,IPR017867,IPR036196; PFAM:PF01451; go_function: GO:0004725 - protein tyrosine phosphatase activity [Evidence IEA]; go_process: GO:0006470 - protein dephosphorylation [Evidence IEA] AKAW2_11676S CAZy:GT2_Chitin_synth; COG:M; EggNog:ENOG410PF8Q; InterPro:IPR029044,IPR004835,IPR004834,IPR013616; PFAM:PF01644,PF08407,PF13632; TransMembrane:7 (o561-580i601-620o640-659i671-694o714-736i842-862o882- 906i); go_function: GO:0004100 - chitin synthase activity [Evidence IEA]; go_function: GO:0016758 - transferase activity, transferring hexosyl groups [Evidence IEA]; go_process: GO:0006031 - chitin biosynthetic process [Evidence IEA] AKAW2_11677A COG:S; EggNog:ENOG410PPBU; InterPro:IPR018908; PFAM:PF10639; TransMembrane:3 (o48-69i174-194o200-220i) AKAW2_11678A COG:S; EggNog:ENOG410PH44; InterPro:IPR029063,IPR016461,IPR036390,IPR036388; go_function: GO:0008168 - methyltransferase activity [Evidence IEA] AKAW2_11679A COG:P,Q; EggNog:ENOG410PJDJ; InterPro:IPR013112,IPR017927,IPR013130,IPR013121, IPR039261; PFAM:PF08022,PF01794,PF08030; TransMembrane:6 (o47-66i122-144o164-182i203-225o245-261i282-311o); go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_11680S COG:P; EggNog:ENOG410PQ6C; InterPro:IPR007274; PFAM:PF04145; TransMembrane:4 (i12-36o42-62i115-132o138-154i); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0005375 - copper ion transmembrane transporter activity [Evidence IEA]; go_process: GO:0035434 - copper ion transmembrane transport [Evidence IEA] AKAW2_11681A COG:O; EggNog:ENOG410PW61; InterPro:IPR027417,IPR000641; go_function: GO:0005524 - ATP binding [Evidence IEA] AKAW2_11682A COG:S; EggNog:ENOG410PPU5; InterPro:IPR029063; PFAM:PF13489 AKAW2_11683A COG:S; EggNog:ENOG410Q04N; SECRETED:SignalP(1-16) AKAW2_11684A COG:Q; EggNog:ENOG410PNWA; InterPro:IPR036291,IPR002347; PFAM:PF00106,PF13561; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_11685S COG:I; EggNog:ENOG410PPX0; InterPro:IPR029058,IPR013094; MEROPS:MER0043003; PFAM:PF07859; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_11686A COG:S; EggNog:ENOG410Q2E9 AKAW2_11687A BUSCO:EOG09263D2P; COG:S; EggNog:ENOG410PIMA; InterPro:IPR000008,IPR037791,IPR035892; PFAM:PF00168 AKAW2_11688S BUSCO:EOG09261MMR; COG:A; EggNog:ENOG410PH3J; InterPro:IPR036322,IPR018983,IPR015943,IPR001680, IPR019775,IPR020472,IPR017986; PFAM:PF09384,PF00400; go_component: GO:0005730 - nucleolus [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0006364 - rRNA processing [Evidence IEA] AKAW2_11689A COG:I; EggNog:ENOG410PM9D; InterPro:IPR008775; PFAM:PF05721 AKAW2_11690A COG:S; EggNog:ENOG410PPZY; TransMembrane:4 (i21-44o97-120i132-155o170-191i) AKAW2_11691A COG:A; EggNog:ENOG410PM4Y; InterPro:IPR000504,IPR031766,IPR011990,IPR035979, IPR012677,IPR034397,IPR034398,IPR003107; PFAM:PF16842,PF00076; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0006396 - RNA processing [Evidence IEA] AKAW2_11692A TransMembrane:1 (i12-33o) AKAW2_11693S BUSCO:EOG09264LC7; COG:J; EggNog:ENOG410PNW5; InterPro:IPR036394,IPR001063,IPR005727; PFAM:PF00237; go_component: GO:0005840 - ribosome [Evidence IEA]; go_component: GO:0015934 - large ribosomal subunit [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_process: GO:0006412 - translation [Evidence IEA] AKAW2_11694A COG:G; EggNog:ENOG410PKMG; InterPro:IPR013078,IPR029033; PFAM:PF00300 AKAW2_11695A COG:S; EggNog:ENOG410PYG0 AKAW2_11696S COG:S; EggNog:ENOG410PTTX; InterPro:IPR001214; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_11697S COG:S; EggNog:ENOG410PX8X; InterPro:IPR018717; PFAM:PF13840,PF10000 AKAW2_11698A COG:S; EggNog:ENOG410PZAI AKAW2_11699S COG:I; EggNog:ENOG410PIIB; InterPro:IPR000873,IPR037337,IPR042099,IPR025110; PFAM:PF00501,PF13193 AKAW2_11700S COG:S; EggNog:ENOG410PM6C; InterPro:IPR002110,IPR027417,IPR007111,IPR036770, IPR020683; PFAM:PF05729,PF12796; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_11701A COG:T; EggNog:ENOG410PK93; InterPro:IPR017441,IPR008271,IPR000719,IPR011009; PFAM:PF07714,PF00069; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_11702A COG:S; EggNog:ENOG410PPE7; InterPro:IPR018613,IPR040233 AKAW2_11703S COG:S; EggNog:ENOG410PGY6; InterPro:IPR029063; PFAM:PF01564; TransMembrane:6 (i21-40o46-63i75-100o112-129i161-181o187-207i) AKAW2_11704A COG:N; EggNog:ENOG410PJG0; InterPro:IPR008467,IPR022780; PFAM:PF05783; go_component: GO:0005868 - cytoplasmic dynein complex [Evidence IEA]; go_process: GO:0007018 - microtubule-based movement [Evidence IEA] AKAW2_11705S COG:S; EggNog:ENOG410PJVW; InterPro:IPR000504,IPR012677,IPR035979; PFAM:PF00076; go_function: GO:0003676 - nucleic acid binding [Evidence IEA] AKAW2_11706A COG:U; EggNog:ENOG410PHY0; InterPro:IPR015943,IPR001680,IPR036322; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_11707S COG:D; EggNog:ENOG410PGVE; InterPro:IPR030379,IPR027417,IPR016491; PFAM:PF00735,PF01926; go_function: GO:0005525 - GTP binding [Evidence IEA] AKAW2_11708S COG:S; EggNog:ENOG410PK9X; InterPro:IPR010730; PFAM:PF06985 AKAW2_11709A COG:T; EggNog:ENOG410PFP7; InterPro:IPR000219,IPR041675,IPR001180,IPR035899, IPR011993,IPR036390,IPR000591,IPR036388; PFAM:PF15405,PF00610,PF00780,PF00621; go_function: GO:0005085 - guanyl-nucleotide exchange factor activity [Evidence IEA]; go_process: GO:0035556 - intracellular signal transduction [Evidence IEA] AKAW2_11710S COG:C; EggNog:ENOG410PMV0; InterPro:IPR011555,IPR035921,IPR000245,IPR002379; PFAM:PF00137; TransMembrane:4 (o12-35i56-77o97-119i131-156o); go_component: GO:0033177 - proton-transporting two-sector ATPase complex, proton-transporting domain [Evidence IEA]; go_component: GO:0033179 - proton-transporting V-type ATPase, V0 domain [Evidence IEA]; go_function: GO:0015078 - proton transmembrane transporter activity [Evidence IEA]; go_process: GO:1902600 - proton transmembrane transport [Evidence IEA] AKAW2_11711S COG:T; EggNog:ENOG410PGKH; InterPro:IPR017441,IPR008271,IPR000961,IPR000719, IPR011009; PFAM:PF07714,PF00069; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0004674 - protein serine/threonine kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_11712A COG:E; EggNog:ENOG410PFDI; InterPro:IPR028939,IPR036291,IPR000304,IPR029036, IPR008927; PFAM:PF03807,PF14748; go_function: GO:0004735 - pyrroline-5-carboxylate reductase activity [Evidence IEA]; go_process: GO:0006561 - proline biosynthetic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_11713A COG:E; EggNog:ENOG410PHWR; InterPro:IPR002872,IPR015659,IPR029041; PFAM:PF01619; go_function: GO:0004657 - proline dehydrogenase activity [Evidence IEA]; go_process: GO:0006562 - proline catabolic process [Evidence IEA] AKAW2_11714S COG:S; EggNog:ENOG410PV21; InterPro:IPR039535; PFAM:PF05935,PF14269; SECRETED:SignalP(1-19); TransMembrane:1 (n4-14c19/20o561-583i) AKAW2_11715S COG:S; EggNog:ENOG410PX01; InterPro:IPR036864,IPR021858,IPR001138; PFAM:PF00172,PF11951; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_11716A COG:E; EggNog:ENOG410PUA5; InterPro:IPR006076,IPR036188; PFAM:PF01266,PF13450; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_11717A COG:E; EggNog:ENOG410PMN3; InterPro:IPR015590,IPR005931,IPR029510,IPR016160, IPR016161,IPR016162,IPR016163; PFAM:PF00171; go_function: GO:0003842 - 1-pyrroline-5-carboxylate dehydrogenase activity [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0016620 - oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Evidence IEA]; go_process: GO:0010133 - proline catabolic process to glutamate [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_11718S COG:S; EggNog:ENOG410PV0T; InterPro:IPR038781; TransMembrane:3 (o20-45i78-97o117-138i) AKAW2_11719S COG:E; EggNog:ENOG410PHHD; InterPro:IPR013057; PFAM:PF01490; TransMembrane:11 (i60-79o85-106i133-156o162-183i190-214o234-255i267- 288o308-327i348-369o381-402i414-437o) AKAW2_11720A COG:S; EggNog:ENOG410PV9X; InterPro:IPR011009,IPR002575; PFAM:PF01636 AKAW2_11721S COG:S; EggNog:ENOG410Q0BW; InterPro:IPR027417,IPR031359,IPR007111; PFAM:PF17100,PF05729 AKAW2_11722S COG:S; EggNog:ENOG410PKHW; InterPro:IPR041472,IPR011761; PFAM:PF13535,PF18130; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0046872 - metal ion binding [Evidence IEA] AKAW2_11723S COG:S; EggNog:ENOG410PJD4; InterPro:IPR011009,IPR002575; PFAM:PF01636 AKAW2_11724A COG:G; EggNog:ENOG410PII4; InterPro:IPR029044,IPR007577,IPR039367; PFAM:PF04488; SECRETED:SignalP(1-23); go_function: GO:0000009 - alpha-1,6-mannosyltransferase activity [Evidence IEA] AKAW2_11725S CAZy:GH43; COG:G; EggNog:ENOG410PUF3; InterPro:IPR023296,IPR006710; PFAM:PF04616; TransMembrane:1 (i62-88o); go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_11726A COG:S; EggNog:ENOG410PJTK; InterPro:IPR036609,IPR004043; PFAM:PF03815; TransMembrane:6 (i129-147o309-342i363-380o431-452i464-487o507-527i) AKAW2_11727S COG:S; EggNog:ENOG410PJJ3; InterPro:IPR009836; PFAM:PF07173 AKAW2_11728A COG:S; EggNog:ENOG410PRB9; InterPro:IPR008253; PFAM:PF01284; TransMembrane:4 (i7-32o44-64i76-102o122-142i); go_component: GO:0016020 - membrane [Evidence IEA] AKAW2_11729S COG:S; EggNog:ENOG410PREZ; InterPro:IPR038071 AKAW2_11730A COG:S; EggNog:ENOG410PH1E; InterPro:IPR025638,IPR036866 AKAW2_11731A BUSCO:EOG092634ZL; COG:S; EggNog:ENOG410PJWR; InterPro:IPR029225,IPR027786,IPR014854; PFAM:PF08743,PF15412; go_component: GO:0005634 - nucleus [Evidence IEA]; go_component: GO:0030915 - Smc5-Smc6 complex [Evidence IEA]; go_process: GO:0006281 - DNA repair [Evidence IEA] AKAW2_11732S BUSCO:EOG0926137U; COG:T; EggNog:ENOG410PFBC; InterPro:IPR001263,IPR015433,IPR002420,IPR016024, IPR036940,IPR008290,IPR018936,IPR035892,IPR042236, IPR011009,IPR000403; PFAM:PF00613,PF00792; go_function: GO:0016301 - kinase activity [Evidence IEA]; go_function: GO:0016303 - 1-phosphatidylinositol-3-kinase activity [Evidence IEA]; go_process: GO:0046854 - phosphatidylinositol phosphorylation [Evidence IEA]; go_process: GO:0048015 - phosphatidylinositol-mediated signaling [Evidence IEA] AKAW2_11733A COG:P; EggNog:ENOG410PHXB; InterPro:IPR003020,IPR011531; TransMembrane:12 (i95-115o135-155i162-179o191-211i218-237o249-272i293- 309o339-363i384-404o454-487i542-561o567-583i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0005452 - inorganic anion exchanger activity [Evidence IEA]; go_process: GO:0006820 - anion transport [Evidence IEA] AKAW2_11734S BUSCO:EOG09262WHU; COG:S; EggNog:ENOG410PK4S; InterPro:IPR027417,IPR006073,IPR016478,IPR023179; PFAM:PF01926; go_function: GO:0005525 - GTP binding [Evidence IEA] AKAW2_11735A BUSCO:EOG09264IOS; COG:A; EggNog:ENOG410PKY9; InterPro:IPR029012,IPR037200,IPR009360; PFAM:PF06246; go_process: GO:0000350 - generation of catalytic spliceosome for second transesterification step [Evidence IEA] AKAW2_11736A COG:Z; EggNog:ENOG410PG6I; InterPro:IPR008989,IPR000048,IPR002928,IPR036961, IPR001609,IPR027417,IPR027401,IPR004009; PFAM:PF02736,PF01576,PF00063; go_component: GO:0016459 - myosin complex [Evidence IEA]; go_function: GO:0003774 - motor activity [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0051015 - actin filament binding [Evidence IEA] AKAW2_11737S COG:S; EggNog:ENOG410PNYB; InterPro:IPR039278,IPR019607; PFAM:PF10650 AKAW2_11739S COG:S; EggNog:ENOG410PMPJ; InterPro:IPR001594; PFAM:PF01529; TransMembrane:4 (i12-32o52-75i216-239o251-278i); go_function: GO:0016409 - palmitoyltransferase activity [Evidence IEA] AKAW2_11740S COG:S; EggNog:ENOG410PRFN AKAW2_11741S COG:S; EggNog:ENOG410PGT1 AKAW2_11742S CAZy:GH17; COG:G; EggNog:ENOG410PGUY; InterPro:IPR017853; TransMembrane:1 (i304-327o) AKAW2_11743A COG:S; EggNog:ENOG410PPV0; InterPro:IPR012942; PFAM:PF07985 AKAW2_11744S COG:S; EggNog:ENOG410PWZU AKAW2_11746S COG:S; EggNog:ENOG410PNID; SECRETED:SignalP(1-25); TransMembrane:1 (n12-20c25/26o226-243i) AKAW2_11747A COG:I; EggNog:ENOG410QDEN; InterPro:IPR000073,IPR029058,IPR000639; MEROPS:MER0017177; PFAM:PF12697,PF00561; go_function: GO:0003824 - catalytic activity [Evidence IEA] AKAW2_11748S COG:S; EggNog:ENOG410PRKZ AKAW2_11749S COG:S; EggNog:ENOG410PN96; InterPro:IPR008991,IPR001884,IPR012340,IPR037318, IPR014722; go_function: GO:0003723 - RNA binding [Evidence IEA]; go_function: GO:0003746 - translation elongation factor activity [Evidence IEA]; go_function: GO:0043022 - ribosome binding [Evidence IEA]; go_process: GO:0045901 - positive regulation of translational elongation [Evidence IEA] AKAW2_11750S COG:G; EggNog:ENOG410PMEJ; InterPro:IPR017996,IPR011042; PFAM:PF03022 AKAW2_11751S COG:C; EggNog:ENOG410PJ9A; InterPro:IPR023210,IPR036812; PFAM:PF00248 AKAW2_11752A BUSCO:EOG09260NE0; COG:B; EggNog:ENOG410QDBI; InterPro:IPR011011,IPR001965,IPR019787,IPR003903; PFAM:PF00628 AKAW2_11754S COG:S; EggNog:ENOG410PK12 AKAW2_11755S COG:S; EggNog:ENOG410PQUE; TransMembrane:4 (i52-71o87-112i124-146o166-183i) AKAW2_11756A COG:S; EggNog:ENOG410PTJ1; InterPro:IPR013860; PFAM:PF08550 AKAW2_11757A COG:S; EggNog:ENOG410PY6U AKAW2_11758S COG:O; EggNog:ENOG410PKZ7; InterPro:IPR027417,IPR003593,IPR003959; PFAM:PF00004; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA] AKAW2_11759A COG:T; EggNog:ENOG410PKHA; InterPro:IPR019819,IPR019826,IPR002018,IPR029058; MEROPS:MER0033188; PFAM:PF00135; TransMembrane:1 (i52-71o) AKAW2_11760S COG:G; EggNog:ENOG410PKV4; InterPro:IPR005829,IPR005828,IPR003663,IPR036259, IPR020846; PFAM:PF00083,PF07690; TransMembrane:12 (i5-24o59-81i93-114o120-138i150-168o180-203i268-298o310- 331i338-356o368-391i403-427o433-454i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_11761S CAZy:GH35; COG:G; EggNog:ENOG410PGTY; InterPro:IPR025300,IPR025972,IPR037110,IPR008979, IPR036833,IPR018954,IPR017853,IPR001944,IPR031330; PFAM:PF13363,PF10435,PF01301,PF13364; SECRETED:SignalP(1-19); go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_11762A CAZy:AA7; COG:C; EggNog:ENOG410PWDY; InterPro:IPR006093,IPR006094,IPR036318,IPR016166, IPR012951; PFAM:PF08031,PF01565; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_function: GO:0071949 - FAD binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_11763S COG:S; EggNog:ENOG410PKJC; SECRETED:SignalP(1-17); TransMembrane:7 (n3-13c17/18o435-454i474-497o509-532i544-566o586-606i691- 713o725-745i) AKAW2_11764A COG:S; EggNog:ENOG410Q2E7; InterPro:IPR000719,IPR011009; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_11765A COG:S; EggNog:ENOG410PMWP; TransMembrane:4 (i126-146o152-171i224-241o247-266i) AKAW2_11766S COG:S; EggNog:ENOG410PNE4; InterPro:IPR010730 AKAW2_11767S COG:S; EggNog:ENOG410PNE4 AKAW2_11768A COG:Q; EggNog:ENOG410PKFE; InterPro:IPR002347,IPR036291,IPR020904; PFAM:PF00106,PF13561,PF08659; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_11769A COG:E,I; EggNog:ENOG410PHUI; InterPro:IPR000089,IPR011761,IPR016185,IPR011764, IPR005479,IPR005482,IPR005481,IPR011054,IPR011053; PFAM:PF02786,PF02222,PF00364,PF02785,PF07478, PF00289; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0046872 - metal ion binding [Evidence IEA] AKAW2_11770S COG:U; EggNog:ENOG410Q1UI AKAW2_11771A COG:I; EggNog:ENOG410PFKB; InterPro:IPR006091,IPR034183,IPR006089,IPR009075, IPR013786,IPR009100,IPR036250,IPR037069; PFAM:PF02770,PF00441,PF02771,PF08028; go_function: GO:0003995 - acyl-CoA dehydrogenase activity [Evidence IEA]; go_function: GO:0016627 - oxidoreductase activity, acting on the CH-CH group of donors [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_11772S COG:E,I; EggNog:ENOG410PKSU; InterPro:IPR011763,IPR011762,IPR029045,IPR034733; PFAM:PF01039; go_function: GO:0016874 - ligase activity [Evidence IEA] AKAW2_11773S COG:I; EggNog:ENOG410PK30; InterPro:IPR013746,IPR016039,IPR013528,IPR010122; PFAM:PF01154,PF08540; go_function: GO:0004421 - hydroxymethylglutaryl-CoA synthase activity [Evidence IEA]; go_function: GO:0016746 - transferase activity, transferring acyl groups [Evidence IEA]; go_process: GO:0006084 - acetyl-CoA metabolic process [Evidence IEA]; go_process: GO:0008299 - isoprenoid biosynthetic process [Evidence IEA]; go_process: GO:0010142 - farnesyl diphosphate biosynthetic process, mevalonate pathway [Evidence IEA] AKAW2_11774A COG:S; EggNog:ENOG410PFUD; InterPro:IPR001806,IPR027417,IPR020849; go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0003924 - GTPase activity [Evidence IEA]; go_function: GO:0005525 - GTP binding [Evidence IEA]; go_process: GO:0007165 - signal transduction [Evidence IEA] AKAW2_11775A COG:S; EggNog:ENOG410PFUD; InterPro:IPR001806,IPR027417,IPR005225,IPR020849; PFAM:PF08477; go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0003924 - GTPase activity [Evidence IEA]; go_function: GO:0005525 - GTP binding [Evidence IEA]; go_process: GO:0007165 - signal transduction [Evidence IEA] AKAW2_11776A TransMembrane:1 (o79-100i) AKAW2_11778A COG:I; EggNog:ENOG410PG26; InterPro:IPR000073,IPR029058; MEROPS:MER0208659; PFAM:PF04083,PF00561; TransMembrane:1 (i12-34o) AKAW2_11779S BUSCO:EOG09265I72; COG:O; EggNog:ENOG410PQRY; InterPro:IPR018793; PFAM:PF10203 AKAW2_11780A COG:O; EggNog:ENOG410PIP1; InterPro:IPR005013; PFAM:PF03345; SECRETED:SignalP(1-19); TransMembrane:1 (n3-14c19/20o424-446i); go_component: GO:0005789 - endoplasmic reticulum membrane [Evidence IEA]; go_process: GO:0018279 - protein N-linked glycosylation via asparagine [Evidence IEA] AKAW2_11781S COG:U; EggNog:ENOG410PS2C; InterPro:IPR039961; TransMembrane:1 (o23-41i) AKAW2_11782A COG:S; EggNog:ENOG410PYEH AKAW2_11783A COG:S; EggNog:ENOG410PRVB AKAW2_11785S BUSCO:EOG09261801; COG:L; EggNog:ENOG410PFN6; InterPro:IPR017961,IPR036775,IPR043502,IPR001126, IPR041298,IPR043128; PFAM:PF00817,PF18439,PF11799; go_function: GO:0003684 - damaged DNA binding [Evidence IEA]; go_process: GO:0006281 - DNA repair [Evidence IEA] AKAW2_11786S COG:S; EggNog:ENOG410PP1R AKAW2_11787S COG:U; EggNog:ENOG410QDU7; InterPro:IPR002889; PFAM:PF01822; SECRETED:SignalP(1-24); TransMembrane:1 (n6-17c24/25o194-218i) AKAW2_11788S COG:S; EggNog:ENOG410PGUC; InterPro:IPR021848; PFAM:PF11927 AKAW2_11789A COG:A; EggNog:ENOG410PMVF; InterPro:IPR005037; PFAM:PF03371 AKAW2_11790A COG:T; EggNog:ENOG410PRPN; InterPro:IPR000719,IPR011009; PFAM:PF00069; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_11791S COG:S; EggNog:ENOG410PYJ4; TransMembrane:1 (o12-32i) AKAW2_11792A BUSCO:EOG092614UB; COG:K; EggNog:ENOG410PHS7; InterPro:IPR015943,IPR001680,IPR036322,IPR017986; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_11793S COG:L; EggNog:ENOG410PJFY; InterPro:IPR041677,IPR027417,IPR041679; PFAM:PF13245,PF13086,PF13087; go_function: GO:0004386 - helicase activity [Evidence IEA] AKAW2_11794S COG:K; EggNog:ENOG410PF8J; InterPro:IPR017441,IPR008271,IPR003527,IPR000719, IPR011009; PFAM:PF07714,PF00069; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0004707 - MAP kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_11795A COG:E; EggNog:ENOG410PJYQ; InterPro:IPR013057; PFAM:PF01490; TransMembrane:11 (i60-77o89-110i131-154o160-181i188-210o237-261i273- 295o315-340i361-387o393-411i423-447o) AKAW2_11796S COG:J; EggNog:ENOG410PFKV; InterPro:IPR023631,IPR036928,IPR000120; PFAM:PF01425; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_11797A COG:Q; EggNog:ENOG410PIRR; InterPro:IPR036291,IPR002347; PFAM:PF08659,PF00106,PF13561; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_11798S COG:S; EggNog:ENOG410PM8D; InterPro:IPR036236,IPR013087,IPR007219; PFAM:PF00096,PF04082; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA] AKAW2_11799A COG:S; EggNog:ENOG410Q259; PFAM:PF13668; SECRETED:SignalP(1-18) AKAW2_11800A COG:Q; EggNog:ENOG410PHP4; InterPro:IPR017871,IPR027417,IPR003593,IPR011527, IPR003439,IPR036640; PFAM:PF00005,PF00664; TransMembrane:17 (o26-46i110-131o137-158i170-189o201-220i305-330o350- 373i475-497o503-522i582-609o615-634i1009-1031o1092- 1112i1167-1188o1194-1214i1279-1302o1308-1328i); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA]; go_function: GO:0042626 - ATPase-coupled transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_11801S COG:O; EggNog:ENOG410PFTE; InterPro:IPR016135,IPR023313,IPR000608; PFAM:PF00179 AKAW2_11802A COG:O; EggNog:ENOG410PFG2; InterPro:IPR023828,IPR000209,IPR034193,IPR010259, IPR022398,IPR015500,IPR036852,IPR037045; MEROPS:MER0000356; PFAM:PF00082,PF05922; SECRETED:SignalP(1-16); go_function: GO:0004252 - serine-type endopeptidase activity [Evidence IEA]; go_function: GO:0008236 - serine-type peptidase activity [Evidence IEA]; go_process: GO:0006508 - proteolysis [Evidence IEA] AKAW2_11804S COG:T,U; EggNog:ENOG410PG0G; InterPro:IPR023362,IPR036372,IPR013320,IPR036322, IPR015943,IPR000409,IPR019775,IPR001680,IPR017986; PFAM:PF02138,PF00400,PF14844,PF13385; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_11805S COG:G; EggNog:ENOG410PI4K; InterPro:IPR004730,IPR018225,IPR013785,IPR001585; PFAM:PF00923; go_component: GO:0005737 - cytoplasm [Evidence IEA]; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0004801 - sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA]; go_process: GO:0006098 - pentose-phosphate shunt [Evidence IEA] AKAW2_11806A SECRETED:SignalP(1-20) AKAW2_11808S COG:P; EggNog:ENOG410PN4F; InterPro:IPR036423,IPR018152,IPR024134,IPR001424; PFAM:PF00080; go_function: GO:0004784 - superoxide dismutase activity [Evidence IEA]; go_function: GO:0046872 - metal ion binding [Evidence IEA]; go_process: GO:0006801 - superoxide metabolic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_11809S COG:K; EggNog:ENOG410PHEC; InterPro:IPR002999,IPR016685,IPR016071,IPR035437; PFAM:PF00567,PF00565; go_component: GO:0016442 - RISC complex [Evidence IEA]; go_process: GO:0031047 - gene silencing by RNA [Evidence IEA] AKAW2_11810S COG:I; EggNog:ENOG410PKSK; InterPro:IPR011074,IPR036865,IPR036273,IPR001251; PFAM:PF00650,PF03765 AKAW2_11811A BUSCO:EOG09260QVP; COG:S; EggNog:ENOG410PIW9; InterPro:IPR015943,IPR011678,IPR026895,IPR018391, IPR002372,IPR011047; PFAM:PF13360,PF07774; SECRETED:SignalP(1-19); TransMembrane:1 (n3-14c19/20o914-934i); go_component: GO:0072546 - ER membrane protein complex [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_11812A COG:S; EggNog:ENOG410PG1Y; InterPro:IPR010856,IPR027443; PFAM:PF07350 AKAW2_11813S COG:Q; EggNog:ENOG410QE03; InterPro:IPR036291,IPR002347,IPR020904; PFAM:PF00106,PF13561; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_11814A COG:S; EggNog:ENOG410PX45 AKAW2_11815S COG:E; EggNog:ENOG410PJ3E; InterPro:IPR013057; PFAM:PF01490; TransMembrane:11 (i34-58o64-84i105-132o158-175i182-203o215-238i259-283o295- 316i367-385o391-413i477-501o) AKAW2_11816A BUSCO:EOG09263K45; COG:T; EggNog:ENOG410PJKI; InterPro:IPR006214; PFAM:PF01027; TransMembrane:7 (i71-91o103-122i129-152o158-176i188-208o214-234i246-266o) AKAW2_11817A COG:U; EggNog:ENOG410PJWS; InterPro:IPR033507,IPR004342,IPR004331; PFAM:PF03105,PF03124; TransMembrane:10 (i488-509o529-553i574-593o599-617i629-645o660-678i690- 711o723-739i751-773o793-815i); go_component: GO:0016021 - integral component of membrane [Evidence IEA] AKAW2_11818A COG:S; EggNog:ENOG410PQZQ; InterPro:IPR022234; PFAM:PF12585 AKAW2_11820S COG:I; EggNog:ENOG410PQ09; InterPro:IPR003140,IPR029058; PFAM:PF02230; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_11821A COG:S; EggNog:ENOG410PHMW; TransMembrane:2 (i504-524o530-547i) AKAW2_11822A COG:T; EggNog:ENOG410PGAU; InterPro:IPR029052,IPR006186,IPR004843,IPR041751, IPR043360; PFAM:PF00149; go_function: GO:0016787 - hydrolase activity [Evidence IEA]; go_function: GO:0033192 - calmodulin-dependent protein phosphatase activity [Evidence IEA]; go_process: GO:0097720 - calcineurin-mediated signaling [Evidence IEA] AKAW2_11823S COG:S; EggNog:ENOG410PPUK AKAW2_11824S COG:S; EggNog:ENOG410PRAA; InterPro:IPR039924,IPR011993; PFAM:PF03517 AKAW2_11825A COG:S; EggNog:ENOG410PZ6D; TransMembrane:1 (o6-30i) AKAW2_11826S COG:Q; EggNog:ENOG410PJRP; InterPro:IPR002347,IPR036291,IPR020904; PFAM:PF00106,PF13561,PF08659; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_11827S COG:S; EggNog:ENOG410Q23F AKAW2_11828S COG:S; EggNog:ENOG410Q1CM AKAW2_11829A COG:A; EggNog:ENOG410PIGH; InterPro:IPR007855; PFAM:PF05183; go_function: GO:0003968 - RNA-directed 5'-3' RNA polymerase activity [Evidence IEA] AKAW2_11830A COG:E; EggNog:ENOG410Q2BV; InterPro:IPR004840,IPR004841; PFAM:PF13520,PF00324; TransMembrane:11 (o46-64i76-97o123-144i156-177o183-206i277-296o333-357i378- 397o409-430i450-468o488-506i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_process: GO:0006865 - amino acid transport [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_11831A COG:S; EggNog:ENOG410PW0S; InterPro:IPR036291,IPR008030; PFAM:PF13460,PF05368 AKAW2_11832S COG:G; EggNog:ENOG410QDJA; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:10 (i61-82o106-128i140-158o196-216i228-248o336-354i361- 381o387-409i421-442o454-475i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_11833A BUSCO:EOG09264I6B; COG:J; EggNog:ENOG410PPRY; InterPro:IPR008991,IPR001857,IPR038657; PFAM:PF01245; go_component: GO:0005840 - ribosome [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_process: GO:0006412 - translation [Evidence IEA] AKAW2_11835S COG:S; EggNog:ENOG410PRD4 AKAW2_11834A COG:S; EggNog:ENOG410PH6R; TransMembrane:1 (o22-42i) AKAW2_11836S COG:S; EggNog:ENOG410PNM2; InterPro:IPR012578; PFAM:PF08058; TransMembrane:2 (o54-78i90-111o) AKAW2_11837S COG:S; EggNog:ENOG410PHI6; InterPro:IPR026705; PFAM:PF12722,PF09742; TransMembrane:1 (i295-312o) AKAW2_11838S COG:S; EggNog:ENOG410PKH3; InterPro:IPR017946,IPR039559; go_function: GO:0008081 - phosphoric diester hydrolase activity [Evidence IEA]; go_process: GO:0006629 - lipid metabolic process [Evidence IEA] AKAW2_11839S BUSCO:EOG09262D4G; COG:S; EggNog:ENOG410PIQJ; InterPro:IPR016849,IPR013178; PFAM:PF08214; go_component: GO:0005634 - nucleus [Evidence IEA]; go_function: GO:0004402 - histone acetyltransferase activity [Evidence IEA]; go_function: GO:0010484 - H3 histone acetyltransferase activity [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA]; go_process: GO:0016573 - histone acetylation [Evidence IEA]; go_process: GO:0043618 - regulation of transcription from RNA polymerase II promoter in response to stress [Evidence IEA] AKAW2_11840S CAZy:GT21; COG:I; EggNog:ENOG410PIM2; InterPro:IPR025993,IPR029044; TransMembrane:3 (o33-55i437-459o499-516i); go_function: GO:0016757 - transferase activity, transferring glycosyl groups [Evidence IEA] AKAW2_11841A COG:S; EggNog:ENOG410PN3C; InterPro:IPR002110,IPR020683,IPR036770; PFAM:PF13857,PF12796,PF00023,PF13637,PF13606; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_11842A COG:S; EggNog:ENOG410PP2Q; InterPro:IPR036020,IPR001202; PFAM:PF00397; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_11843S COG:O; EggNog:ENOG410PZ95; InterPro:IPR001338; PFAM:PF01185; go_component: GO:0009277 - fungal-type cell wall [Evidence IEA]; go_function: GO:0005199 - structural constituent of cell wall [Evidence IEA] AKAW2_11845A COG:S; EggNog:ENOG410PHSS; InterPro:IPR004136,IPR013785; PFAM:PF03060,PF00478; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0018580 - nitronate monooxygenase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_11847S BUSCO:EOG09262H50; COG:J; EggNog:ENOG410PJ45; InterPro:IPR014816,IPR029063; PFAM:PF08704; go_component: GO:0031515 - tRNA (m1A) methyltransferase complex [Evidence IEA]; go_function: GO:0016429 - tRNA (adenine-N1-)-methyltransferase activity [Evidence IEA]; go_process: GO:0030488 - tRNA methylation [Evidence IEA] AKAW2_11846A COG:S; EggNog:ENOG410PJMR; InterPro:IPR009060,IPR036869,IPR015940,IPR011990; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_11848S COG:S; EggNog:ENOG410PI0G; InterPro:IPR012469 AKAW2_11849S BUSCO:EOG09264IV9; COG:U; EggNog:ENOG410PIE6; InterPro:IPR027417,IPR006762,IPR039397; PFAM:PF04670,PF00025,PF08477,PF00071,PF01926; go_function: GO:0005525 - GTP binding [Evidence IEA] AKAW2_11850S TransMembrane:2 (i21-37o105-123i) AKAW2_11851A COG:U; EggNog:ENOG410PGQF; InterPro:IPR022775,IPR001392,IPR011012,IPR036168, IPR028565,IPR018240; PFAM:PF01217,PF00928; go_component: GO:0030131 - clathrin adaptor complex [Evidence IEA]; go_process: GO:0006886 - intracellular protein transport [Evidence IEA]; go_process: GO:0016192 - vesicle-mediated transport [Evidence IEA] AKAW2_11852A COG:S; EggNog:ENOG410PNPU; InterPro:IPR040030,IPR000999,IPR036389; PFAM:PF00636,PF14622; go_component: GO:0005762 - mitochondrial large ribosomal subunit [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_function: GO:0004525 - ribonuclease III activity [Evidence IEA]; go_process: GO:0006396 - RNA processing [Evidence IEA]; go_process: GO:0032543 - mitochondrial translation [Evidence IEA] AKAW2_11854A COG:C; EggNog:ENOG410PNR7; InterPro:IPR018495,IPR014314,IPR034804,IPR000701; PFAM:PF01127; TransMembrane:2 (i86-106o118-135i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0045281 - succinate dehydrogenase complex [Evidence IEA]; go_function: GO:0000104 - succinate dehydrogenase activity [Evidence IEA]; go_function: GO:0009055 - electron transfer activity [Evidence IEA]; go_function: GO:0016627 - oxidoreductase activity, acting on the CH-CH group of donors [Evidence IEA]; go_process: GO:0006099 - tricarboxylic acid cycle [Evidence IEA] AKAW2_11855S COG:G; EggNog:ENOG410PJER; InterPro:IPR018225,IPR013785,IPR001585; PFAM:PF00923; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_11856A BUSCO:EOG09260B65; COG:J; EggNog:ENOG410PGHV; InterPro:IPR016024,IPR011989,IPR040017,IPR013598; PFAM:PF08389; go_function: GO:0000049 - tRNA binding [Evidence IEA]; go_function: GO:0008536 - Ran GTPase binding [Evidence IEA]; go_process: GO:0006409 - tRNA export from nucleus [Evidence IEA]; go_process: GO:0071528 - tRNA re-export from nucleus [Evidence IEA] AKAW2_11857A BUSCO:EOG09261HZD; COG:G; EggNog:ENOG410PGX4; InterPro:IPR018485,IPR018484,IPR042024,IPR043129; PFAM:PF00370,PF02782; go_function: GO:0004856 - xylulokinase activity [Evidence IEA]; go_function: GO:0016773 - phosphotransferase activity, alcohol group as acceptor [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA]; go_process: GO:0042732 - D-xylose metabolic process [Evidence IEA] AKAW2_11858A COG:P; EggNog:ENOG410PGYD; InterPro:IPR027469,IPR002524; PFAM:PF01545; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0008324 - cation transmembrane transporter activity [Evidence IEA]; go_process: GO:0006812 - cation transport [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_11859S COG:S; EggNog:ENOG410PK8R; InterPro:IPR009836; PFAM:PF07173 AKAW2_11860A InterPro:IPR001810,IPR036047; PFAM:PF00646; SECRETED:SignalP(1-20); go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_11861A COG:S; EggNog:ENOG410PURZ AKAW2_11862S COG:S; EggNog:ENOG410PIPA; InterPro:IPR000571; go_function: GO:0046872 - metal ion binding [Evidence IEA] AKAW2_11863A CAZy:CE1; COG:S; EggNog:ENOG410PI1S; InterPro:IPR000801,IPR014186,IPR029058; MEROPS:MER0043126; PFAM:PF00326,PF00756; go_function: GO:0018738 - S-formylglutathione hydrolase activity [Evidence IEA]; go_process: GO:0046294 - formaldehyde catabolic process [Evidence IEA] AKAW2_11864A BUSCO:EOG092603JK; COG:D; EggNog:ENOG410PHZC; InterPro:IPR030397,IPR005314,IPR011990; MEROPS:MER0010982; PFAM:PF03568; go_component: GO:0005634 - nucleus [Evidence IEA]; go_function: GO:0004197 - cysteine-type endopeptidase activity [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0006508 - proteolysis [Evidence IEA] AKAW2_11865S COG:S; EggNog:ENOG410PRQC; InterPro:IPR035213; PFAM:PF17254; TransMembrane:1 (o81-100i) AKAW2_11866A COG:C; EggNog:ENOG410PFJQ; InterPro:IPR011992,IPR023395,IPR018108,IPR002048, IPR018247,IPR002067; PFAM:PF00036,PF13405,PF00153,PF13202,PF13499; TransMembrane:1 (o276-296i); go_function: GO:0005509 - calcium ion binding [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_11867A COG:S; EggNog:ENOG410PM27; InterPro:IPR026841; PFAM:PF14378; TransMembrane:7 (o6-23i71-91o152-171i183-200o231-252i259-280o286-307i) AKAW2_11868S COG:S; EggNog:ENOG410PIN4; InterPro:IPR021840; PFAM:PF11915; TransMembrane:8 (i26-44o70-89i135-154o485-503i593-619o639-660i705- 728o1050-1072i) AKAW2_11869S COG:S; EggNog:ENOG410PYU9 AKAW2_11870S COG:O; EggNog:ENOG410PGPJ; InterPro:IPR017860,IPR017861,IPR000905,IPR043129, IPR022450; go_process: GO:0002949 - tRNA threonylcarbamoyladenosine modification [Evidence IEA] AKAW2_11871A COG:S; EggNog:ENOG410PU5Y AKAW2_11872S BUSCO:EOG092618M2; COG:B,K; EggNog:ENOG410PFPU; InterPro:IPR019542,IPR019787,IPR019786,IPR011011, IPR034732,IPR001965,IPR013083; PFAM:PF10513,PF13832,PF00628,PF13771,PF13831 AKAW2_11873S COG:S; EggNog:ENOG410PNZQ; InterPro:IPR000504,IPR012677,IPR035979; PFAM:PF00076; go_function: GO:0003676 - nucleic acid binding [Evidence IEA] AKAW2_11874A COG:S; EggNog:ENOG410PTFD; InterPro:IPR007858; PFAM:PF05186 AKAW2_11875S COG:S; EggNog:ENOG410PJWP; InterPro:IPR011856,IPR014883,IPR033315; PFAM:PF08774; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0004518 - nuclease activity [Evidence IEA]; go_function: GO:0016788 - hydrolase activity, acting on ester bonds [Evidence IEA]; go_process: GO:0036297 - interstrand cross-link repair [Evidence IEA] AKAW2_11876A BUSCO:EOG0926514P; COG:J; EggNog:ENOG410PMVC; InterPro:IPR009068,IPR000589,IPR023029,IPR012606; PFAM:PF08069,PF00312; go_component: GO:0005840 - ribosome [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_process: GO:0006412 - translation [Evidence IEA] AKAW2_11877S COG:S; EggNog:ENOG410PKEB; InterPro:IPR017981; TransMembrane:7 (o87-109i121-140o160-180i201-223o243-270i312-333o378- 399i); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0004888 - transmembrane signaling receptor activity [Evidence IEA]; go_process: GO:0007166 - cell surface receptor signaling pathway [Evidence IEA] AKAW2_11878A COG:A; EggNog:ENOG410PJ8F; InterPro:IPR000504,IPR012677,IPR006529,IPR035979; PFAM:PF00076; go_component: GO:0005634 - nucleus [Evidence IEA]; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0003723 - RNA binding [Evidence IEA]; go_process: GO:0006397 - mRNA processing [Evidence IEA] AKAW2_11879S COG:L; EggNog:ENOG410PIA2; InterPro:IPR003265,IPR012904,IPR023170,IPR011257; PFAM:PF07934,PF00730; go_function: GO:0003684 - damaged DNA binding [Evidence IEA]; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0008534 - oxidized purine nucleobase lesion DNA N-glycosylase activity [Evidence IEA]; go_process: GO:0006281 - DNA repair [Evidence IEA]; go_process: GO:0006284 - base-excision repair [Evidence IEA]; go_process: GO:0006289 - nucleotide-excision repair [Evidence IEA] AKAW2_11880A COG:S; EggNog:ENOG410PHYQ; InterPro:IPR036864,IPR021858,IPR001138; PFAM:PF11951; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_11881A BUSCO:EOG092605VU; COG:S; EggNog:ENOG410PHY5; InterPro:IPR015915,IPR011043; PFAM:PF12768; TransMembrane:1 (n3-14c19/20o1143-1166i); go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_11882S BUSCO:EOG09261WVT; COG:K; EggNog:ENOG410PHIH; InterPro:IPR024954,IPR035417,IPR000969,IPR011993, IPR013719,IPR038167; PFAM:PF17292,PF08512,PF03531; go_component: GO:0005634 - nucleus [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA] AKAW2_11883S COG:D; EggNog:ENOG410PGWY; InterPro:IPR030379,IPR027417,IPR016491; PFAM:PF00735,PF01926; go_function: GO:0005525 - GTP binding [Evidence IEA] AKAW2_11884S COG:S; EggNog:ENOG410PGKI; InterPro:IPR005344; PFAM:PF03661; TransMembrane:3 (i24-50o56-74i194-219o); go_component: GO:0016021 - integral component of membrane [Evidence IEA] AKAW2_11885S COG:C; EggNog:ENOG410PHPK; InterPro:IPR018108,IPR023395; PFAM:PF00153; TransMembrane:2 (i130-152o168-186i) AKAW2_11886S COG:S; EggNog:ENOG410PNJA; InterPro:IPR038872; TransMembrane:3 (o232-255i276-295o319-340i) AKAW2_11887A COG:H; EggNog:ENOG410PMIX; InterPro:IPR016966,IPR036759,IPR007373,IPR036371, IPR007371; PFAM:PF04263,PF04265; go_function: GO:0004788 - thiamine diphosphokinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0030975 - thiamine binding [Evidence IEA]; go_process: GO:0009229 - thiamine diphosphate biosynthetic process [Evidence IEA] AKAW2_11888A COG:M; EggNog:ENOG410PJJV; InterPro:IPR002110,IPR036770,IPR020683; PFAM:PF12796,PF00023,PF13637; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_11889S BUSCO:EOG092651BA; COG:O; EggNog:ENOG410PQPT; InterPro:IPR010625,IPR039289; PFAM:PF06747; go_function: GO:0015035 - protein disulfide oxidoreductase activity [Evidence IEA]; go_process: GO:0045041 - protein import into mitochondrial intermembrane space [Evidence IEA] AKAW2_11890A BUSCO:EOG09260BZ0; COG:A; EggNog:ENOG410PGB8; InterPro:IPR016024,IPR016021,IPR003890,IPR039762, IPR007193; PFAM:PF02854,PF04050; go_function: GO:0003723 - RNA binding [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0000184 - nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [Evidence IEA] AKAW2_11892A COG:S; EggNog:ENOG410PKEK; InterPro:IPR000253; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_11893A CAZy:GH132; COG:S; EggNog:ENOG410PFHK; InterPro:IPR005556; PFAM:PF03856; SECRETED:SignalP(1-19) AKAW2_11894S TransMembrane:2 (i45-64o70-86i) AKAW2_11895S BUSCO:EOG092649VG; COG:C; EggNog:ENOG410PFFW; InterPro:IPR033947,IPR014731,IPR014730,IPR001308, IPR014729,IPR029035; PFAM:PF00766,PF01012; go_function: GO:0009055 - electron transfer activity [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA] AKAW2_11896A COG:S; EggNog:ENOG410PN46; InterPro:IPR023674,IPR028364,IPR016095; PFAM:PF00687 AKAW2_11897A BUSCO:EOG09260N2T; COG:L; EggNog:ENOG410PG1B; InterPro:IPR003959,IPR027417,IPR003593; PFAM:PF00004,PF13401,PF07728; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA] AKAW2_11898A COG:L; EggNog:ENOG410PG1B AKAW2_11900A COG:J; EggNog:ENOG410PGET; InterPro:IPR016024,IPR011989,IPR040533,IPR017871, IPR027417,IPR003593,IPR003439,IPR015688; PFAM:PF00005,PF17947; antiSMASH:Cluster_1.18; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA] AKAW2_11901S TransMembrane:1 (o159-177i); antiSMASH:Cluster_1.18 AKAW2_11902S antiSMASH:Cluster_1.18 AKAW2_11903S SECRETED:SignalP(1-31); antiSMASH:Cluster_1.18 AKAW2_11904A COG:Q; EggNog:ENOG410PHH6; InterPro:IPR001128,IPR036396; PFAM:PF00067; SMCOG1034:cytochrome P450; TransMembrane:4 (i64-82o94-112i124-145o532-552i); antiSMASH:Cluster_1.18; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_11905S COG:S; EggNog:ENOG410Q20Z; InterPro:IPR033964,IPR017795,IPR012148; MEROPS:MER0066227; PFAM:PF11991; antiSMASH:Cluster_1.18; go_function: GO:0016765 - transferase activity, transferring alkyl or aryl (other than methyl) groups [Evidence IEA]; go_process: GO:0009820 - alkaloid metabolic process [Evidence IEA] AKAW2_11906S COG:G; EggNog:ENOG410PF8Z; InterPro:IPR020846,IPR005828,IPR036259; PFAM:PF07690,PF00083; SMCOG1169:sugar transport protein; TransMembrane:10 (i66-84o104-126i133-151o157-178i190-213o225-243i279- 297o317-340i347-366o445-466i); antiSMASH:Cluster_1.18; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_11907S BUSCO:EOG09262KN8; COG:U; EggNog:ENOG410PGPB; InterPro:IPR012908,IPR039529,IPR029058; PFAM:PF12697,PF07819; TransMembrane:10 (i114-135o783-801i831-849o881-899i906-926o946-977i998- 1021o1041-1058i1070-1089o1095-1112i); antiSMASH:Cluster_1.18; go_function: GO:0016788 - hydrolase activity, acting on ester bonds [Evidence IEA] AKAW2_11909S COG:S; EggNog:ENOG410PU6N; antiSMASH:Cluster_1.18 AKAW2_11908A antiSMASH:Cluster_1.18 AKAW2_11910A COG:S; EggNog:ENOG410PV1W; InterPro:IPR011009 AKAW2_11911A COG:S; EggNog:ENOG410PV1W; TransMembrane:2 (o6-25i37-55o) AKAW2_11912A COG:S; EggNog:ENOG410PS4Z AKAW2_11913S COG:I; EggNog:ENOG410Q4K2; InterPro:IPR019826,IPR002018,IPR029058; MEROPS:MER0033241; PFAM:PF00135; SECRETED:SignalP(1-21) AKAW2_11916A COG:U; EggNog:ENOG410PIM9; InterPro:IPR016024,IPR011990,IPR000547; PFAM:PF00637; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0006886 - intracellular protein transport [Evidence IEA]; go_process: GO:0016192 - vesicle-mediated transport [Evidence IEA] AKAW2_11917A COG:S; EggNog:ENOG410PRCF; TransMembrane:7 (o12-32i44-63o100-121i133-153o184-203i215-235o247-274i) AKAW2_11918A COG:S; EggNog:ENOG410PHD3; InterPro:IPR032805; PFAM:PF13813; TransMembrane:6 (n8-19c23/24o33-55i62-83o188-213i280-297o309-331i352- 371o) AKAW2_11919S COG:Q; EggNog:ENOG410PK4R; InterPro:IPR001128,IPR002403,IPR036396; PFAM:PF00067; TransMembrane:2 (o22-39i314-334o); go_function: GO:0004497 - monooxygenase activity [Evidence IEA]; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_11920A COG:S; EggNog:ENOG410PQVD AKAW2_11921A COG:S; EggNog:ENOG410PNPP; TransMembrane:7 (o25-49i61-82o102-128i140-163o183-209i221-240o260-278i) AKAW2_11922A CAZy:AA7; COG:C; EggNog:ENOG410PKNQ; InterPro:IPR016166,IPR006094,IPR036318; PFAM:PF01565; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_function: GO:0071949 - FAD binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_11923S COG:S; EggNog:ENOG410PPHV; InterPro:IPR039601; go_component: GO:0000500 - RNA polymerase I upstream activating factor complex [Evidence IEA]; go_process: GO:0042790 - nucleolar large rRNA transcription by RNA polymerase I [Evidence IEA] AKAW2_11924S COG:O; EggNog:ENOG410PHHE; InterPro:IPR036249,IPR036282,IPR010987,IPR004045, IPR004046; PFAM:PF13409,PF00043,PF14497,PF13410,PF13417, PF02798; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0006749 - glutathione metabolic process [Evidence IEA] AKAW2_11925S COG:B; EggNog:ENOG410PFJS; InterPro:IPR009057,IPR017884,IPR036388,IPR041984, IPR032451,IPR007526,IPR001005; PFAM:PF16495,PF00249,PF13921,PF04433; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_11927S COG:S; EggNog:ENOG410PRA5 AKAW2_11926A COG:S; EggNog:ENOG410PS02; InterPro:IPR008011; PFAM:PF05347 AKAW2_11928S COG:K; EggNog:ENOG410PGG6; InterPro:IPR018004,IPR036887,IPR036770,IPR020683, IPR003163; PFAM:PF13637; go_function: GO:0003677 - DNA binding [Evidence IEA] AKAW2_11929S BUSCO:EOG09260UXC; COG:L; EggNog:ENOG410PFUP; InterPro:IPR013026,IPR011990,IPR019734; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_11930A COG:S; EggNog:ENOG410PIKW; InterPro:IPR029063,IPR010286; PFAM:PF05971; go_function: GO:0008168 - methyltransferase activity [Evidence IEA] AKAW2_11931S COG:I; EggNog:ENOG410PKYE; InterPro:IPR016555,IPR015679,IPR001736; PFAM:PF00614; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0004630 - phospholipase D activity [Evidence IEA]; go_process: GO:0006654 - phosphatidic acid biosynthetic process [Evidence IEA]; go_process: GO:0048017 - inositol lipid-mediated signaling [Evidence IEA] AKAW2_11933A COG:F; EggNog:ENOG410PFQH; InterPro:IPR029057,IPR000836,IPR000842,IPR029099, IPR005946; PFAM:PF14572,PF13793; go_function: GO:0000287 - magnesium ion binding [Evidence IEA]; go_function: GO:0004749 - ribose phosphate diphosphokinase activity [Evidence IEA]; go_process: GO:0009116 - nucleoside metabolic process [Evidence IEA]; go_process: GO:0009156 - ribonucleoside monophosphate biosynthetic process [Evidence IEA]; go_process: GO:0009165 - nucleotide biosynthetic process [Evidence IEA]; go_process: GO:0044249 - cellular biosynthetic process [Evidence IEA] AKAW2_11934S COG:H; EggNog:ENOG410PFN2; InterPro:IPR006367,IPR028281,IPR028161,IPR028162, IPR036291; PFAM:PF13241,PF14823,PF14824; go_function: GO:0004325 - ferrochelatase activity [Evidence IEA]; go_function: GO:0043115 - precorrin-2 dehydrogenase activity [Evidence IEA]; go_process: GO:0006779 - porphyrin-containing compound biosynthetic process [Evidence IEA]; go_process: GO:0019354 - siroheme biosynthetic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_11935A BUSCO:EOG092602UY; COG:U; EggNog:ENOG410PG3R; InterPro:IPR016024,IPR035999,IPR023394,IPR032629, IPR032691,IPR015403,IPR000904; PFAM:PF16213,PF12783,PF09324,PF01369; go_function: GO:0005086 - ARF guanyl-nucleotide exchange factor activity [Evidence IEA]; go_process: GO:0032012 - regulation of ARF protein signal transduction [Evidence IEA] AKAW2_11936S COG:C; EggNog:ENOG410PGQ4; InterPro:IPR036625,IPR000089,IPR001078,IPR004167, IPR023213,IPR003016,IPR006257,IPR011053; PFAM:PF00364,PF00198,PF02817; go_component: GO:0045254 - pyruvate dehydrogenase complex [Evidence IEA]; go_function: GO:0004742 - dihydrolipoyllysine-residue acetyltransferase activity [Evidence IEA]; go_function: GO:0016746 - transferase activity, transferring acyl groups [Evidence IEA]; go_process: GO:0006090 - pyruvate metabolic process [Evidence IEA] AKAW2_11937S COG:S; EggNog:ENOG410PR1V; InterPro:IPR039453,IPR039454; PFAM:PF17304; TransMembrane:2 (i104-124o136-154i); go_component: GO:0031307 - integral component of mitochondrial outer membrane [Evidence IEA]; go_function: GO:1990593 - nascent polypeptide-associated complex binding [Evidence IEA] AKAW2_11938S COG:U; EggNog:ENOG410PJYZ; InterPro:IPR027027; PFAM:PF12352; TransMembrane:1 (i222-242o); go_component: GO:0005794 - Golgi apparatus [Evidence IEA]; go_function: GO:0005484 - SNAP receptor activity [Evidence IEA]; go_process: GO:0016192 - vesicle-mediated transport [Evidence IEA] AKAW2_11939S COG:C; EggNog:ENOG410PGCI; InterPro:IPR015955,IPR001236,IPR036291,IPR001557, IPR010097,IPR001252,IPR022383; PFAM:PF00056,PF02866; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0016615 - malate dehydrogenase activity [Evidence IEA]; go_function: GO:0016616 - oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Evidence IEA]; go_function: GO:0030060 - L-malate dehydrogenase activity [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA]; go_process: GO:0006099 - tricarboxylic acid cycle [Evidence IEA]; go_process: GO:0006108 - malate metabolic process [Evidence IEA]; go_process: GO:0019752 - carboxylic acid metabolic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_11940A COG:O; EggNog:ENOG410PG6Z; InterPro:IPR027417,IPR003593,IPR003959; PFAM:PF00004; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA] AKAW2_11941S COG:S; EggNog:ENOG410PXTQ AKAW2_11942A COG:S; EggNog:ENOG410PIJU; InterPro:IPR013745; PFAM:PF08539; TransMembrane:1 (o585-608i) AKAW2_11944S COG:S; EggNog:ENOG410PTB0; InterPro:IPR014849; PFAM:PF08738 AKAW2_11943A BUSCO:EOG09260OCI; COG:U; EggNog:ENOG410PHR7; InterPro:IPR019453,IPR019452,IPR001180,IPR032914, IPR000547; PFAM:PF10367,PF10366,PF00780; go_process: GO:0006886 - intracellular protein transport [Evidence IEA]; go_process: GO:0016192 - vesicle-mediated transport [Evidence IEA] AKAW2_11945A COG:G; EggNog:ENOG410PIZY; InterPro:IPR013079,IPR013078,IPR027417,IPR001345, IPR003094,IPR029033; PFAM:PF00300,PF01591; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0003873 - 6-phosphofructo-2-kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006000 - fructose metabolic process [Evidence IEA]; go_process: GO:0006003 - fructose 2,6-bisphosphate metabolic process [Evidence IEA] AKAW2_11946A COG:A; EggNog:ENOG410PQRD; InterPro:IPR000504,IPR012677,IPR035979; PFAM:PF00076; go_function: GO:0003676 - nucleic acid binding [Evidence IEA] AKAW2_11947A COG:C; EggNog:ENOG410PFFH; InterPro:IPR027545,IPR036188,IPR002938; PFAM:PF01494; TransMembrane:1 (o460-487i); go_function: GO:0004502 - kynurenine 3-monooxygenase activity [Evidence IEA]; go_function: GO:0071949 - FAD binding [Evidence IEA]; go_process: GO:0006569 - tryptophan catabolic process [Evidence IEA]; go_process: GO:0019805 - quinolinate biosynthetic process [Evidence IEA] AKAW2_11948S COG:S; EggNog:ENOG410PYTI; InterPro:IPR014710,IPR011051; TransMembrane:1 (o239-259i) AKAW2_11949A COG:G; EggNog:ENOG410PHGF; InterPro:IPR005828,IPR003663,IPR036259,IPR020846; PFAM:PF00083,PF07690; TransMembrane:10 (i199-221o233-254i296-316o328-347i419-440o460-481i488- 510o516-537i558-577o589-608i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_11950S COG:S; EggNog:ENOG410PJAS; InterPro:IPR006680,IPR032466,IPR032465; PFAM:PF04909; go_function: GO:0016787 - hydrolase activity [Evidence IEA]; go_function: GO:0016831 - carboxy-lyase activity [Evidence IEA] AKAW2_11951A COG:S; EggNog:ENOG410Q21V AKAW2_11952A COG:O; EggNog:ENOG410PJZX; InterPro:IPR013083,IPR011016; PFAM:PF12906; TransMembrane:3 (o158-184i221-241o261-278i); go_function: GO:0008270 - zinc ion binding [Evidence IEA] AKAW2_11953S BUSCO:EOG092645G0; COG:O; EggNog:ENOG410PHVE; InterPro:IPR029055,IPR034644,IPR001353,IPR023332, IPR000426; MEROPS:MER0004996; PFAM:PF00227,PF10584; go_component: GO:0005839 - proteasome core complex [Evidence IEA]; go_component: GO:0019773 - proteasome core complex, alpha-subunit complex [Evidence IEA]; go_process: GO:0006511 - ubiquitin-dependent protein catabolic process [Evidence IEA]; go_process: GO:0051603 - proteolysis involved in cellular protein catabolic process [Evidence IEA] AKAW2_11954S COG:S; EggNog:ENOG410Q1TV; TransMembrane:7 (o28-50i57-78o90-109i121-138o177-195i207-231o237-258i) AKAW2_11955A COG:S; EggNog:ENOG410PPMP; InterPro:IPR013632,IPR027417,IPR020588; PFAM:PF08423; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0008094 - DNA-dependent ATPase activity [Evidence IEA]; go_process: GO:0006281 - DNA repair [Evidence IEA] AKAW2_11956A COG:O; EggNog:ENOG410PFN8; InterPro:IPR024079,IPR024077,IPR024080,IPR001567; MEROPS:MER0003110; PFAM:PF01432; go_function: GO:0004222 - metalloendopeptidase activity [Evidence IEA]; go_function: GO:0008237 - metallopeptidase activity [Evidence IEA]; go_process: GO:0006508 - proteolysis [Evidence IEA] AKAW2_11957A COG:I; EggNog:ENOG410Q2RD; InterPro:IPR001199,IPR001522,IPR015876,IPR005804, IPR036400,IPR018506; PFAM:PF00173; TransMembrane:2 (i34-52o58-83i); go_function: GO:0016717 - oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0006629 - lipid metabolic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_11958A COG:I; EggNog:ENOG410Q2RD; InterPro:IPR015876; TransMembrane:2 (i36-57o63-84i); go_function: GO:0016717 - oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_11959S COG:P; EggNog:ENOG410PFK4; InterPro:IPR006042,IPR006043; PFAM:PF00860; TransMembrane:11 (o122-139i151-171o199-220i227-245o280-299i311-330o350- 367i437-459o465-484i496-515o535-557i); go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_11960S COG:U; EggNog:ENOG410PUQI; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:8 (i12-40o46-63i131-150o170-188i200-218o233-261i282-304o310- 330i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_11962A COG:E,O; EggNog:ENOG410PHV7; InterPro:IPR018202,IPR001563,IPR029058; MEROPS:MER0003541; PFAM:PF00450; SECRETED:SignalP(1-18); go_function: GO:0004185 - serine-type carboxypeptidase activity [Evidence IEA]; go_process: GO:0006508 - proteolysis [Evidence IEA] AKAW2_11963S COG:S; EggNog:ENOG410Q1DU AKAW2_11964A COG:M; EggNog:ENOG410PKAU; InterPro:IPR002110,IPR027417,IPR007111,IPR036770, IPR020683; PFAM:PF13857,PF05729,PF12796,PF00023,PF13606, PF13637; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_11965A COG:S; EggNog:ENOG410PKYB; InterPro:IPR005302,IPR005303,IPR011037; PFAM:PF03473; TransMembrane:2 (i21-42o512-532i); go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0030151 - molybdenum ion binding [Evidence IEA]; go_function: GO:0030170 - pyridoxal phosphate binding [Evidence IEA] AKAW2_11966A COG:E; EggNog:ENOG410PW8E; InterPro:IPR037523,IPR041735,IPR041736,IPR029068, IPR004360,IPR005956; PFAM:PF00903; go_function: GO:0003868 - 4-hydroxyphenylpyruvate dioxygenase activity [Evidence IEA]; go_function: GO:0016701 - oxidoreductase activity, acting on single donors with incorporation of molecular oxygen [Evidence IEA]; go_process: GO:0009072 - aromatic amino acid family metabolic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_11968S COG:C,H; EggNog:ENOG410PGID; InterPro:IPR036188,IPR002938,IPR036249,IPR038220, IPR012941; PFAM:PF07976,PF01494; go_function: GO:0071949 - FAD binding [Evidence IEA] AKAW2_11969S COG:C; EggNog:ENOG410PI5D; InterPro:IPR037458,IPR001199,IPR037396,IPR013785, IPR036400,IPR000262; PFAM:PF00173,PF01070; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA] AKAW2_11970A COG:S; EggNog:ENOG410PWFA; InterPro:IPR011717,IPR011990,IPR035994; PFAM:PF07721; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_function: GO:0042802 - identical protein binding [Evidence IEA]; go_process: GO:0009116 - nucleoside metabolic process [Evidence IEA] AKAW2_11971A COG:Q; EggNog:ENOG410PKXD; InterPro:IPR036291,IPR002347; PFAM:PF08659,PF00106,PF13561; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_11972A COG:S; EggNog:ENOG410PZQA; SECRETED:SignalP(1-19) AKAW2_11973A COG:S; EggNog:ENOG410PYAH AKAW2_11975S InterPro:IPR008999,IPR022768; PFAM:PF06268; go_function: GO:0030674 - protein-macromolecule adaptor activity [Evidence IEA]; go_function: GO:0051015 - actin filament binding [Evidence IEA] AKAW2_11978S COG:Q; EggNog:ENOG410PV9C; InterPro:IPR008775; PFAM:PF05721 AKAW2_11977A COG:S; EggNog:ENOG410PX5I; InterPro:IPR036864,IPR021858,IPR001138; PFAM:PF00172; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_11979S COG:S; EggNog:ENOG410PVIV; InterPro:IPR004104,IPR000683,IPR036291; PFAM:PF02894,PF01408; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA] AKAW2_11980S COG:S; EggNog:ENOG410PU7Z; InterPro:IPR036864,IPR021858,IPR001138; PFAM:PF00172; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_11981A COG:S; EggNog:ENOG410QDYX; InterPro:IPR036864,IPR021858,IPR001138; PFAM:PF00172; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_11982A COG:S; EggNog:ENOG410PJR7; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_11983A COG:S; EggNog:ENOG410PG4U; InterPro:IPR000073,IPR029058; MEROPS:MER0209971; PFAM:PF12697 AKAW2_11984S COG:S; EggNog:ENOG410PSVD AKAW2_11985A BUSCO:EOG09265591; COG:T; EggNog:ENOG410PMCV; InterPro:IPR002048,IPR011992; PFAM:PF13833,PF13499; go_function: GO:0005509 - calcium ion binding [Evidence IEA] AKAW2_11986A COG:K; EggNog:ENOG410PFUT; InterPro:IPR036236,IPR013087,IPR007219; PFAM:PF00096,PF04082; TransMembrane:1 (o926-942i); go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA] AKAW2_11988A BUSCO:EOG09260Z5E; COG:U; EggNog:ENOG410PFXQ; InterPro:IPR001494,IPR016024,IPR013598,IPR011989; PFAM:PF08389; go_function: GO:0008536 - Ran GTPase binding [Evidence IEA]; go_process: GO:0006886 - intracellular protein transport [Evidence IEA] AKAW2_11989S BUSCO:EOG09265NHW; COG:A; EggNog:ENOG410PS8Z; InterPro:IPR027078,IPR010920,IPR001163; PFAM:PF01423; go_component: GO:0005681 - spliceosomal complex [Evidence IEA]; go_process: GO:0000398 - mRNA splicing, via spliceosome [Evidence IEA] AKAW2_11990A COG:H; EggNog:ENOG410PPHN; InterPro:IPR024185,IPR037171,IPR002698; PFAM:PF01812 AKAW2_11991S COG:U; EggNog:ENOG410PFUS; InterPro:IPR019623; PFAM:PF10681; SECRETED:SignalP(1-17); TransMembrane:1 (n2-13c21/22o218-234i); go_component: GO:0005783 - endoplasmic reticulum [Evidence IEA]; go_process: GO:0006458 - 'de novo' protein folding [Evidence IEA] AKAW2_11992A COG:S; EggNog:ENOG410PQB3; InterPro:IPR003789,IPR019004,IPR042184; PFAM:PF09424; go_function: GO:0016884 - carbon-nitrogen ligase activity, with glutamine as amido-N-donor [Evidence IEA] AKAW2_11993S BUSCO:EOG092606UX; COG:U,Y; EggNog:ENOG410PHQ9; InterPro:IPR042538,IPR042537,IPR014908,IPR004870, IPR042533,IPR007187; PFAM:PF03177,PF08801; go_component: GO:0005643 - nuclear pore [Evidence IEA]; go_function: GO:0017056 - structural constituent of nuclear pore [Evidence IEA]; go_process: GO:0006913 - nucleocytoplasmic transport [Evidence IEA] AKAW2_11994A COG:I; EggNog:ENOG410PHDX; InterPro:IPR042098,IPR003819; PFAM:PF02668; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_11996S COG:S; EggNog:ENOG410PS4P; InterPro:IPR016964,IPR033118; PFAM:PF05241; TransMembrane:4 (i17-39o71-91i103-127o139-159i) AKAW2_11997A COG:L; EggNog:ENOG410PI87; InterPro:IPR021109,IPR009060,IPR019103,IPR015940, IPR000626,IPR029071; MEROPS:MER0030081; PFAM:PF00240,PF09668,PF13650,PF00627,PF13975; go_function: GO:0004190 - aspartic-type endopeptidase activity [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0006508 - proteolysis [Evidence IEA] AKAW2_11998S COG:S; EggNog:ENOG410PSXP; InterPro:IPR011008 AKAW2_11999A COG:C,H; EggNog:ENOG410PK0A; InterPro:IPR010451,IPR036188,IPR002938,IPR023375; PFAM:PF01494,PF06314; TransMembrane:1 (i12-31o); go_function: GO:0016829 - lyase activity [Evidence IEA]; go_function: GO:0071949 - FAD binding [Evidence IEA] AKAW2_12000S COG:S; EggNog:ENOG410PHT6; InterPro:IPR008979,IPR029058,IPR005674,IPR013736, IPR000383; PFAM:PF02129,PF08530; go_function: GO:0008239 - dipeptidyl-peptidase activity [Evidence IEA]; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_12001S COG:S; EggNog:ENOG410PP69; InterPro:IPR014710,IPR011051,IPR013096; PFAM:PF07883 AKAW2_12002A COG:S; EggNog:ENOG410PST1 AKAW2_12003S COG:S; EggNog:ENOG410PN8Z; InterPro:IPR015590,IPR016161,IPR016162,IPR016163; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0016620 - oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_12004A COG:S; EggNog:ENOG410PJMW; InterPro:IPR014436,IPR004183; PFAM:PF02900; go_function: GO:0008198 - ferrous iron binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0016701 - oxidoreductase activity, acting on single donors with incorporation of molecular oxygen [Evidence IEA]; go_process: GO:0006725 - cellular aromatic compound metabolic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_12005S COG:K; EggNog:ENOG410QEEY; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; TransMembrane:1 (o702-723i); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_12006A COG:S; EggNog:ENOG410PFNZ; InterPro:IPR029063; PFAM:PF13649,PF13489,PF08242,PF08241,PF13847 AKAW2_12007S COG:S; EggNog:ENOG410PJ3X; InterPro:IPR036188,IPR002938; go_function: GO:0071949 - FAD binding [Evidence IEA] AKAW2_12008A COG:S; EggNog:ENOG410Q2VN; InterPro:IPR022085; PFAM:PF12311 AKAW2_12009S COG:O; EggNog:ENOG410PT8R; InterPro:IPR023112,IPR022706; PFAM:PF11402; SECRETED:SignalP(1-18) AKAW2_12010A COG:G; EggNog:ENOG410PMHX; InterPro:IPR005829,IPR005828,IPR003663,IPR036259, IPR020846; PFAM:PF00083,PF07690; TransMembrane:11 (o106-125i137-155o161-182i194-215o227-248i315-337o352- 373i380-402o414-436i448-466o478-497i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_12011S COG:Q; EggNog:ENOG410PVDZ; InterPro:IPR013154,IPR013149,IPR002328,IPR036291, IPR011032,IPR020843; PFAM:PF00107,PF08240,PF16912; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_12012A COG:K; EggNog:ENOG410PXX0; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; TransMembrane:2 (i240-257o584-604i); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_12013S COG:S; EggNog:ENOG410PGN5; InterPro:IPR025340; PFAM:PF14033 AKAW2_12014A SECRETED:SignalP(1-28) AKAW2_12015A COG:S; EggNog:ENOG410PTHV; InterPro:IPR008427; PFAM:PF05730; SECRETED:SignalP(1-20) AKAW2_12016S CAZy:GH55; COG:S; EggNog:ENOG410PKNM; InterPro:IPR012334,IPR011050,IPR024535; PFAM:PF12708 AKAW2_12017S COG:G; EggNog:ENOG410PG0X; InterPro:IPR005828,IPR003663,IPR036259,IPR020846; PFAM:PF00083,PF07690; TransMembrane:11 (o38-59i71-89o95-116i128-148o160-180i255-279o291-313i320- 339o345-372i393-410o416-434i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_12018S COG:Q; EggNog:ENOG410Q2DA; InterPro:IPR043926,IPR027417,IPR003593,IPR010929, IPR017871,IPR029481,IPR003439,IPR013525,IPR034003; PFAM:PF01061,PF00005,PF06422,PF14510; TransMembrane:13 (o483-503i515-537o557-580i592-613o619-640i729-746o1140- 1160i1172-1195o1215-1243i1255-1275o1281-1301i1308- 1326o1408-1427i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA]; go_function: GO:0042626 - ATPase-coupled transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_12019A COG:Q; EggNog:ENOG410PUZA; InterPro:IPR013149,IPR036291,IPR011032,IPR020843; PFAM:PF00107,PF13602; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_12020A COG:S; EggNog:ENOG410PUU6; InterPro:IPR029058 AKAW2_12021S CAZy:GH16; COG:G; EggNog:ENOG410PH2Y; InterPro:IPR000757,IPR013320,IPR017168; PFAM:PF00722; SECRETED:SignalP(1-19); go_component: GO:0005618 - cell wall [Evidence IEA]; go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_function: GO:0016798 - hydrolase activity, acting on glycosyl bonds [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA]; go_process: GO:0071555 - cell wall organization [Evidence IEA] AKAW2_12022A COG:H; EggNog:ENOG410PG02; InterPro:IPR036188,IPR002937,IPR008150,IPR014105; PFAM:PF13450,PF01593; TransMembrane:1 (o523-543i); go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0016117 - carotenoid biosynthetic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_12023A InterPro:IPR007657; PFAM:PF04577; SECRETED:SignalP(1-23); go_function: GO:0016757 - transferase activity, transferring glycosyl groups [Evidence IEA] AKAW2_12024A COG:I; EggNog:ENOG410PVGT; InterPro:IPR002656; PFAM:PF01757; TransMembrane:10 (i12-30o61-87i108-129o149-172i184-202o208-236i257-277o307- 325i337-358o384-409i); go_function: GO:0016747 - transferase activity, transferring acyl groups other than amino-acyl groups [Evidence IEA] AKAW2_12026S COG:M; EggNog:ENOG410PJTB; InterPro:IPR029044; PFAM:PF13506,PF13632,PF13641; TransMembrane:6 (i28-45o51-67i422-445o482-500i521-543o555-576i); antiSMASH:Cluster_1.19 AKAW2_12027A COG:O; EggNog:ENOG410PMZQ; InterPro:IPR036249,IPR040079,IPR036282,IPR010987, IPR004045; PFAM:PF13409,PF13417,PF00462,PF02798; SMCOG1193:glutathione S-transferase; antiSMASH:Cluster_1.19; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0006749 - glutathione metabolic process [Evidence IEA] AKAW2_12028A COG:G; EggNog:ENOG410PHMI; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; SMCOG1005:Drug resistance transporter, EmrB/QacA; TransMembrane:10 (i133-152o172-195i216-236o248-268i324-342o362-384i404- 424o430-450i462-489o501-524i); antiSMASH:Cluster_1.19; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_12029A COG:S; EggNog:ENOG410PX0V; InterPro:IPR010730; PFAM:PF06985; antiSMASH:Cluster_1.19 AKAW2_12030A COG:S; EggNog:ENOG410PU0M; InterPro:IPR000719,IPR011009; antiSMASH:Cluster_1.19; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_12031A COG:S; EggNog:ENOG410PSHX; InterPro:IPR018392,IPR036779; PFAM:PF01476; antiSMASH:Cluster_1.19 AKAW2_12032S antiSMASH:Cluster_1.19 AKAW2_12033A COG:Q; EggNog:ENOG410PVV8; InterPro:IPR009081,IPR036736,IPR036291,IPR020806, IPR013968; PFAM:PF00550,PF08659; antiSMASH:Cluster_1.19; go_function: GO:0031177 - phosphopantetheine binding [Evidence IEA] AKAW2_12034A COG:Q; EggNog:ENOG410PVV8; InterPro:IPR016036,IPR016035,IPR016039,IPR042104, IPR014030,IPR011032,IPR013154,IPR001227,IPR013217, IPR032821,IPR014031,IPR014043,IPR020807,IPR020843, IPR020841,IPR013149,IPR029063,IPR036291; PFAM:PF16197,PF00109,PF13489,PF02801,PF00698, PF13847,PF13649,PF14765,PF00107,PF08242,PF08240,PF08241; SMCOG1022:Beta-ketoacyl synthase; antiSMASH:Cluster_1.19; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0016740 - transferase activity [Evidence IEA]; go_function: GO:0016746 - transferase activity, transferring acyl groups [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_12035S COG:Q; EggNog:ENOG410PVJW; InterPro:IPR001128,IPR017972,IPR002401,IPR036396; PFAM:PF00067; SMCOG1034:cytochrome P450; antiSMASH:Cluster_1.19; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_12036A COG:G; EggNog:ENOG410PM5G; InterPro:IPR032506,IPR017850,IPR000917; PFAM:PF00884,PF01663; antiSMASH:Cluster_1.19; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0008484 - sulfuric ester hydrolase activity [Evidence IEA] AKAW2_12037S COG:S; EggNog:ENOG410PH7P; InterPro:IPR012334,IPR011050; SECRETED:SignalP(1-18); antiSMASH:Cluster_1.19 AKAW2_12038S COG:S; EggNog:ENOG410PH7P; InterPro:IPR000743,IPR012334,IPR011050; antiSMASH:Cluster_1.19; go_function: GO:0004650 - polygalacturonase activity [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_12039S COG:G; EggNog:ENOG410QEIP; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; SMCOG1106:major facilitator transporter; TransMembrane:10 (i106-123o177-195i202-225o237-258i270-292o383-406i413- 432o438-454i475-496o511-529i); antiSMASH:Cluster_1.19; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_12040S COG:S; EggNog:ENOG410PN5J; InterPro:IPR007568; PFAM:PF04479; TransMembrane:7 (o20-40i47-66o86-111i123-141o161-186i207-227o239-259i); antiSMASH:Cluster_1.19; go_component: GO:0016021 - integral component of membrane [Evidence IEA] AKAW2_12041S COG:O; EggNog:ENOG410PNP1; InterPro:IPR034164,IPR021109,IPR001461,IPR001969, IPR033121; MEROPS:MER0081262; PFAM:PF00026; SECRETED:SignalP(1-18); antiSMASH:Cluster_1.19; go_function: GO:0004190 - aspartic-type endopeptidase activity [Evidence IEA]; go_process: GO:0006508 - proteolysis [Evidence IEA] AKAW2_12042A COG:M; EggNog:ENOG410PQCH; InterPro:IPR002110,IPR036770,IPR020683; PFAM:PF12796,PF13637,PF13606; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_12043S COG:S; EggNog:ENOG410PM9X; InterPro:IPR007568; PFAM:PF04479; TransMembrane:7 (o20-42i49-68o80-108i120-145o157-183i204-224o244-263i); go_component: GO:0016021 - integral component of membrane [Evidence IEA] AKAW2_12044A COG:S; EggNog:ENOG410PZZF; InterPro:IPR036864,IPR021858,IPR001138; PFAM:PF00172; TransMembrane:3 (o226-245i421-438o450-471i); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_12045S COG:C; EggNog:ENOG410Q2DB; InterPro:IPR044152,IPR001155,IPR013785; PFAM:PF00724; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0003959 - NADPH dehydrogenase activity [Evidence IEA]; go_function: GO:0010181 - FMN binding [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0050661 - NADP binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_12046A COG:C; EggNog:ENOG410PM5N; InterPro:IPR011032,IPR020843,IPR013154,IPR036291; PFAM:PF08240; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_12047A COG:I; EggNog:ENOG410PGSV; InterPro:IPR006091,IPR029320,IPR012258,IPR002655, IPR037069,IPR009100,IPR036250; PFAM:PF02770,PF01756,PF14749; go_component: GO:0005777 - peroxisome [Evidence IEA]; go_function: GO:0003997 - acyl-CoA oxidase activity [Evidence IEA]; go_function: GO:0016627 - oxidoreductase activity, acting on the CH-CH group of donors [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_function: GO:0071949 - FAD binding [Evidence IEA]; go_process: GO:0006631 - fatty acid metabolic process [Evidence IEA]; go_process: GO:0006635 - fatty acid beta-oxidation [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_12048A COG:Q; EggNog:ENOG410PIRX; InterPro:IPR026992,IPR027443,IPR005123; PFAM:PF03171,PF14226; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_12049A COG:C; EggNog:ENOG410PKHE; InterPro:IPR012133,IPR037396,IPR008259,IPR013785, IPR000262; PFAM:PF01070; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0010181 - FMN binding [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_12050S COG:S; EggNog:ENOG410PUC2; InterPro:IPR036291,IPR016040; PFAM:PF13460; SMCOG1010:NAD-dependent epimerase/dehydratase; antiSMASH:Cluster_1.20 AKAW2_12051S COG:S; EggNog:ENOG410PHC5; InterPro:IPR021858; PFAM:PF11951; antiSMASH:Cluster_1.20 AKAW2_12052A COG:E; EggNog:ENOG410PNE3; InterPro:IPR002220,IPR020624,IPR013785; PFAM:PF00701; antiSMASH:Cluster_1.20; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0016829 - lyase activity [Evidence IEA] AKAW2_12053S COG:C; EggNog:ENOG410PJ9J; InterPro:IPR015590,IPR029510,IPR016161,IPR016162, IPR016163; PFAM:PF00171; SMCOG1017:aldehyde dehydrogenase; antiSMASH:Cluster_1.20; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0016620 - oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_12054A COG:S; EggNog:ENOG410PMWB; InterPro:IPR039653,IPR000537; PFAM:PF01040; TransMembrane:4 (i146-164o263-282i289-307o319-339i); antiSMASH:Cluster_1.20; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0016765 - transferase activity, transferring alkyl or aryl (other than methyl) groups [Evidence IEA] AKAW2_12055A COG:I; EggNog:ENOG410PM2C; InterPro:IPR017825,IPR008949,IPR019845; PFAM:PF00494; TransMembrane:8 (o6-25i37-60o80-98i119-138o144-162i169-187o218-239i414- 433o); antiSMASH:Cluster_1.20; go_function: GO:0016765 - transferase activity, transferring alkyl or aryl (other than methyl) groups [Evidence IEA]; go_function: GO:0016872 - intramolecular lyase activity [Evidence IEA] AKAW2_12056A COG:P; EggNog:ENOG410Q07G; InterPro:IPR036922,IPR017941,IPR015879,IPR001663; PFAM:PF00355; antiSMASH:Cluster_1.20; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0051537 - 2 iron, 2 sulfur cluster binding [Evidence IEA]; go_process: GO:0044237 - cellular metabolic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_12057A COG:G; EggNog:ENOG410QD9V; InterPro:IPR011701,IPR036259; PFAM:PF07690; SMCOG1137:Major facilitator superfamily MFS 1; TransMembrane:12 (i23-43o63-81i93-111o117-138i150-170o182-201i221-241o261- 280i292-311o317-343i355-376o388-410i); antiSMASH:Cluster_1.20; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_12058S COG:I; EggNog:ENOG410PUUA; InterPro:IPR023606,IPR003673; PFAM:PF02515; SMCOG1189:L-carnitine dehydratase/bile acid-inducible; antiSMASH:Cluster_1.20; go_function: GO:0008410 - CoA-transferase activity [Evidence IEA] AKAW2_12059S COG:S; EggNog:ENOG410PKV0; InterPro:IPR007219; PFAM:PF04082; antiSMASH:Cluster_1.20; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA] AKAW2_12060S COG:Q; EggNog:ENOG410PQAF; InterPro:IPR036291,IPR002347; PFAM:PF00106,PF13561; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_12061S COG:Q; EggNog:ENOG410PIXU; InterPro:IPR015889; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016702 - oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_12062S COG:E; EggNog:ENOG410PURD; InterPro:IPR015424,IPR001597,IPR015422,IPR015421; PFAM:PF01212; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0016829 - lyase activity [Evidence IEA]; go_process: GO:0006520 - cellular amino acid metabolic process [Evidence IEA] AKAW2_12063S COG:S; EggNog:ENOG410PNA2; InterPro:IPR007219; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA] AKAW2_12064S COG:U; EggNog:ENOG410Q19X; SECRETED:SignalP(1-18); TransMembrane:1 (n6-16c20/21o171-193i) AKAW2_12065S COG:I; EggNog:ENOG410PMTP; InterPro:IPR042098,IPR003819; PFAM:PF02668; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_12066A COG:S; EggNog:ENOG410PIT7; InterPro:IPR007219; PFAM:PF04082; TransMembrane:3 (i31-49o99-116i309-331o); go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA] AKAW2_12067A COG:S; EggNog:ENOG410PIT7; InterPro:IPR001138,IPR036864; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_12068S COG:S; EggNog:ENOG410PJ7E; InterPro:IPR000073,IPR029058; PFAM:PF12697 AKAW2_12069A COG:U; EggNog:ENOG410Q2V4; InterPro:IPR011042,IPR011659; PFAM:PF07676 AKAW2_12070A COG:U; EggNog:ENOG410Q2V4; InterPro:IPR011042,IPR011659; PFAM:PF07676; SECRETED:SignalP(1-18) AKAW2_12071A COG:S; EggNog:ENOG410PSDH; TransMembrane:7 (o12-39i51-74o94-117i129-150o179-201i213-235o247-267i) AKAW2_12072S COG:I; EggNog:ENOG410PT1I; InterPro:IPR036188,IPR002938; PFAM:PF01494; TransMembrane:1 (o6-26i); go_function: GO:0071949 - FAD binding [Evidence IEA] AKAW2_12073A COG:S; EggNog:ENOG410PZ01; InterPro:IPR036291,IPR008030; PFAM:PF13460,PF05368 AKAW2_12074S COG:Q; EggNog:ENOG410PHH6; InterPro:IPR001128,IPR002401,IPR036396; PFAM:PF00067; TransMembrane:3 (o6-23i35-57o63-84i); go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_12075S COG:O; EggNog:ENOG410PPG1; InterPro:IPR036249,IPR040079,IPR036282,IPR010987, IPR004045,IPR004046; PFAM:PF13409,PF00043,PF14497,PF13417,PF02798; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0006749 - glutathione metabolic process [Evidence IEA] AKAW2_12076A COG:S; EggNog:ENOG410PZ20; InterPro:IPR024078,IPR003737; PFAM:PF02585 AKAW2_12077A COG:S; EggNog:ENOG410PXY0; InterPro:IPR036291,IPR016040; PFAM:PF13460 AKAW2_12078A COG:O; EggNog:ENOG410Q2AN; InterPro:IPR024079,IPR024077,IPR024080,IPR001567; MEROPS:MER0003110; PFAM:PF01432; go_function: GO:0004222 - metalloendopeptidase activity [Evidence IEA]; go_function: GO:0008237 - metallopeptidase activity [Evidence IEA]; go_process: GO:0006508 - proteolysis [Evidence IEA] AKAW2_12079S CAZy:AA3; COG:E; EggNog:ENOG410PJ6X; InterPro:IPR012132,IPR036188,IPR027424,IPR000172, IPR007867; PFAM:PF00732,PF05199; go_function: GO:0016614 - oxidoreductase activity, acting on CH-OH group of donors [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_12080A COG:O; EggNog:ENOG410PKER; InterPro:IPR029058,IPR005152; PFAM:PF03583; SECRETED:SignalP(1-19); go_function: GO:0004806 - triglyceride lipase activity [Evidence IEA]; go_process: GO:0016042 - lipid catabolic process [Evidence IEA] AKAW2_12081A COG:Q; EggNog:ENOG410PNVS; InterPro:IPR002347,IPR036291; PFAM:PF00106,PF13561,PF08659,PF01370; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_12082S COG:Q; EggNog:ENOG410PHWX; InterPro:IPR036291,IPR002347; PFAM:PF00106,PF13561,PF01370; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_12083A COG:E; EggNog:ENOG410PGKT; InterPro:IPR002821,IPR008040,IPR010318,IPR027479, IPR043129; PFAM:PF01968,PF05378,PF06032; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_12084S COG:F,H; EggNog:ENOG410PJYB; InterPro:IPR038271,IPR001248; PFAM:PF02133; TransMembrane:11 (o43-63i70-87o93-110i122-144o164-183i190-211o231-249i269- 289o382-408i433-456o468-492i); go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_12085S COG:G; EggNog:ENOG410QDX4; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i45-64o84-105i112-130o136-156i177-199o205-223i274- 297o324-344i365-387o393-421i433-450o462-482i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_12086A CAZy:GH31; COG:G; EggNog:ENOG410Q21M; InterPro:IPR017853,IPR011013,IPR000322,IPR013780; PFAM:PF01055; SECRETED:SignalP(1-21); go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_function: GO:0030246 - carbohydrate binding [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_12087S COG:S; EggNog:ENOG410PZQA; SECRETED:SignalP(1-16) AKAW2_12088A COG:S; EggNog:ENOG410PNSB; InterPro:IPR038656,IPR000250,IPR013320; MEROPS:MER0003426; PFAM:PF01828; SECRETED:SignalP(1-18); go_function: GO:0004190 - aspartic-type endopeptidase activity [Evidence IEA]; go_process: GO:0006508 - proteolysis [Evidence IEA] AKAW2_12089S COG:E; EggNog:ENOG410PHU6; TransMembrane:1 (i45-65o) AKAW2_12090S COG:E; EggNog:ENOG410PHU6; InterPro:IPR002293; PFAM:PF00324,PF13520; TransMembrane:8 (o31-55i67-91o103-121i201-224o244-266i305-323o329-346i366- 399o); go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_12091S COG:S; EggNog:ENOG410QDXZ; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i21-43o63-81i88-106o118-136i148-172o178-197i248-274o286- 306i334-355o361-381i393-416o428-450i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_12092A COG:I; EggNog:ENOG410PJ85; InterPro:IPR001753,IPR029045; PFAM:PF16113,PF00378; go_function: GO:0003824 - catalytic activity [Evidence IEA] AKAW2_12093A COG:S; EggNog:ENOG410PJ7E; InterPro:IPR029058 AKAW2_12094A COG:S; EggNog:ENOG410PJ7E; InterPro:IPR029058 AKAW2_12095A COG:I; EggNog:ENOG410PHRI; InterPro:IPR011009,IPR002575,IPR041726; PFAM:PF01636 AKAW2_12096A COG:Q; EggNog:ENOG410Q1ER; InterPro:IPR001128,IPR002403,IPR017972,IPR036396; PFAM:PF00067; TransMembrane:2 (i12-30o36-55i); go_function: GO:0004497 - monooxygenase activity [Evidence IEA]; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_12097S CAZy:CBM67; CAZy:GH78; COG:S; EggNog:ENOG410PJDQ; InterPro:IPR008928,IPR013783,IPR035396,IPR008902, IPR013737,IPR035398,IPR012341; PFAM:PF17390,PF17389,PF05592,PF08531; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_12098S COG:G; EggNog:ENOG410PK1K; InterPro:IPR005829,IPR005828,IPR003663,IPR036259, IPR020846; PFAM:PF00083,PF07690; TransMembrane:9 (n4-14c32/33o48-67i79-97o103-124i136-155o167-188i295- 316o322-342i354-378o421-441i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_12099A COG:S; EggNog:ENOG410PIKI AKAW2_12100A SECRETED:SignalP(1-18) AKAW2_12101S CAZy:GH18; COG:G; EggNog:ENOG410PMRY; InterPro:IPR036861,IPR011583,IPR029070,IPR001223, IPR017853,IPR018392,IPR001002,IPR001579,IPR036779; PFAM:PF00704,PF01476; SECRETED:SignalP(1-19); TransMembrane:3 (n3-14c19/20o1148-1167i1174-1194o1206-1226i); go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_function: GO:0008061 - chitin binding [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_12102A COG:S; EggNog:ENOG410PIA0; TransMembrane:7 (o20-39i51-72o92-118i130-150o174-197i209-229o249-267i) AKAW2_12103S COG:S; EggNog:ENOG410PRG9; InterPro:IPR000073,IPR029058; PFAM:PF12697 AKAW2_12104A COG:S; EggNog:ENOG410PX6E; InterPro:IPR029063; PFAM:PF13489,PF13649 AKAW2_12105S COG:S; EggNog:ENOG410PRIH; SECRETED:SignalP(1-22) AKAW2_12106A COG:S; EggNog:ENOG410Q07U; SECRETED:SignalP(1-20) AKAW2_20001S COG:S; EggNog:ENOG410PQEA AKAW2_20002A COG:G; EggNog:ENOG410PFF2; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i40-62o74-95i107-124o130-153i165-189o195-215i283-302o314- 338i373-392o404-427i439-457o463-487i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_20003S InterPro:IPR011584,IPR009017; PFAM:PF01353; go_process: GO:0008218 - bioluminescence [Evidence IEA] AKAW2_20004S InterPro:IPR007219; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA] AKAW2_20005A COG:E; EggNog:ENOG410PI69; InterPro:IPR020855,IPR023696,IPR006035; PFAM:PF00491; SECRETED:SignalP(1-19); go_function: GO:0016813 - hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines [Evidence IEA]; go_function: GO:0046872 - metal ion binding [Evidence IEA] AKAW2_20006S COG:G; EggNog:ENOG410PHZT; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:14 (i20-45o65-84i91-113o119-142i154-173o185-207i219-240o252- 271i291-311o323-349i356-375o381-406i418-437o457-475i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_20007S COG:S; EggNog:ENOG410PS9Y; InterPro:IPR011008,IPR007138; PFAM:PF03992 AKAW2_20008S COG:S; EggNog:ENOG410PS9Y AKAW2_20009A COG:Q; EggNog:ENOG410PIJR; InterPro:IPR001128,IPR002403,IPR017972,IPR036396; TransMembrane:1 (i12-31o); go_function: GO:0004497 - monooxygenase activity [Evidence IEA]; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_20010S COG:Q; EggNog:ENOG410PVG3; InterPro:IPR026992,IPR027443,IPR005123; PFAM:PF03171,PF14226; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_20011S COG:S; EggNog:ENOG410PX5I; InterPro:IPR021858; PFAM:PF11951 AKAW2_20012S SECRETED:SignalP(1-17) AKAW2_20013A COG:S; EggNog:ENOG410Q2VS; InterPro:IPR029063,IPR016461,IPR001077; PFAM:PF00891; go_function: GO:0008168 - methyltransferase activity [Evidence IEA]; go_function: GO:0008171 - O-methyltransferase activity [Evidence IEA] AKAW2_20014A COG:S; EggNog:ENOG410PHAX; InterPro:IPR029063,IPR016461,IPR001077,IPR036390; PFAM:PF00891; go_function: GO:0008168 - methyltransferase activity [Evidence IEA]; go_function: GO:0008171 - O-methyltransferase activity [Evidence IEA] AKAW2_20016S COG:Q; EggNog:ENOG410PUCS; InterPro:IPR001128,IPR002401,IPR036396; PFAM:PF00067; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_20017S COG:S; EggNog:ENOG410PVBI; SECRETED:SignalP(1-20) AKAW2_20018A COG:S; EggNog:ENOG410PU5C AKAW2_20019A COG:I; EggNog:ENOG410PJJG; InterPro:IPR005804; PFAM:PF00487; TransMembrane:5 (o47-71i83-105o117-137i241-260o272-292i); go_process: GO:0006629 - lipid metabolic process [Evidence IEA] AKAW2_20020A COG:E; EggNog:ENOG410PJCN; InterPro:IPR036152,IPR006034,IPR004550,IPR027475, IPR027474,IPR020827,IPR027473,IPR040919,IPR037152; PFAM:PF00710,PF17763; go_function: GO:0004067 - asparaginase activity [Evidence IEA]; go_process: GO:0006520 - cellular amino acid metabolic process [Evidence IEA]; go_process: GO:0006528 - asparagine metabolic process [Evidence IEA] AKAW2_20021A COG:E; EggNog:ENOG410PWAP; InterPro:IPR010349; PFAM:PF06089 AKAW2_20022S COG:I; EggNog:ENOG410Q2EG; InterPro:IPR007312,IPR017850; SECRETED:SignalP(1-18); antiSMASH:Cluster_2.1; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0016788 - hydrolase activity, acting on ester bonds [Evidence IEA] AKAW2_20023S COG:I; EggNog:ENOG410Q2EG; InterPro:IPR007312,IPR017850; antiSMASH:Cluster_2.1; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0016788 - hydrolase activity, acting on ester bonds [Evidence IEA] AKAW2_20024A COG:S; EggNog:ENOG410PMUA; InterPro:IPR043504,IPR008256,IPR009003; MEROPS:MER0001513; antiSMASH:Cluster_2.1; go_function: GO:0008236 - serine-type peptidase activity [Evidence IEA]; go_process: GO:0006508 - proteolysis [Evidence IEA] AKAW2_20025A COG:P; EggNog:ENOG410PGDX; InterPro:IPR005829,IPR005828,IPR020846,IPR036259; PFAM:PF07690; SMCOG1074:major facilitator family transporter; TransMembrane:12 (i48-68o88-107i119-139o145-166i187-212o224-245i272- 289o309-334i346-365o371-395i407-431o443-463i); antiSMASH:Cluster_2.1; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_20026S COG:E; EggNog:ENOG410PKWI; InterPro:IPR036005,IPR029149,IPR000994; MEROPS:MER0005715; PFAM:PF00557; SMCOG1172:methionine aminopeptidase; TransMembrane:1 (i29-47o); antiSMASH:Cluster_2.1 AKAW2_20027S COG:S; EggNog:ENOG410Q2JQ; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; TransMembrane:1 (o558-577i); antiSMASH:Cluster_2.1; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_20028A COG:G; EggNog:ENOG410PHFT; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; SMCOG1106:major facilitator transporter; TransMembrane:9 (o6-33i45-67o79-101i152-172o184-203i215-233o239-263i275- 296o308-329i); antiSMASH:Cluster_2.1; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_20029S antiSMASH:Cluster_2.1 AKAW2_20030A COG:S; EggNog:ENOG410PKHJ; InterPro:IPR007325,IPR037175; PFAM:PF04199; antiSMASH:Cluster_2.1; go_function: GO:0004061 - arylformamidase activity [Evidence IEA]; go_process: GO:0019441 - tryptophan catabolic process to kynurenine [Evidence IEA] AKAW2_20031S COG:C; EggNog:ENOG410PFVQ; InterPro:IPR018170,IPR020471,IPR036812,IPR023210; PFAM:PF00248; SMCOG1039:aldo/keto reductase family oxidoreductase; antiSMASH:Cluster_2.1; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_20032S COG:S; EggNog:ENOG410PHZM; TransMembrane:6 (o20-46i53-72o84-107i119-147o167-187i199-220o); antiSMASH:Cluster_2.1 AKAW2_20033S COG:Q; EggNog:ENOG410PIAK; InterPro:IPR000873,IPR020845,IPR009081,IPR006162, IPR036291,IPR027417,IPR036736,IPR018247,IPR020806, IPR013120,IPR042099,IPR006001; PFAM:PF00501,PF01202,PF13671,PF00550,PF01370, PF07993; SMCOG1002:AMP-dependent synthetase and ligase; antiSMASH:Cluster_2.1; go_function: GO:0016301 - kinase activity [Evidence IEA]; go_function: GO:0031177 - phosphopantetheine binding [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_20034A COG:S; EggNog:ENOG410PUK0; InterPro:IPR000073,IPR029058; PFAM:PF12697; antiSMASH:Cluster_2.1 AKAW2_20035A COG:S; EggNog:ENOG410PNVY; TransMembrane:1 (o281-302i); antiSMASH:Cluster_2.1 AKAW2_20036S COG:S; EggNog:ENOG410PSTM; SECRETED:SignalP(1-20); TransMembrane:1 (n4-15c22/23o155-174i); antiSMASH:Cluster_2.1 AKAW2_20037A COG:O; EggNog:ENOG410PWH7; InterPro:IPR011118,IPR029058; PFAM:PF07519; SECRETED:SignalP(1-49); antiSMASH:Cluster_2.1 AKAW2_20038S COG:E; EggNog:ENOG410PWAR; InterPro:IPR024688,IPR018357,IPR011004,IPR001451; PFAM:PF14602,PF00132,PF12464; SMCOG1156:Chloramphenicol acetyltransferase; antiSMASH:Cluster_2.1; go_function: GO:0016407 - acetyltransferase activity [Evidence IEA]; go_function: GO:0016740 - transferase activity [Evidence IEA] AKAW2_20039A COG:Q; EggNog:ENOG410PUUN; InterPro:IPR013154,IPR013149,IPR036291,IPR011032, IPR020843; PFAM:PF00107,PF08240,PF13602; SMCOG1028:crotonyl-CoA reductase / alcohol dehydrogenase; antiSMASH:Cluster_2.1; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_20040S COG:S; EggNog:ENOG410PW3E; InterPro:IPR036236,IPR013087,IPR007219; PFAM:PF00096,PF04082; TransMembrane:1 (o699-718i); antiSMASH:Cluster_2.1; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA] AKAW2_20041A COG:C; EggNog:ENOG410PVVZ; InterPro:IPR012951; PFAM:PF08031; antiSMASH:Cluster_2.1; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_20042A COG:C; EggNog:ENOG410PVVZ; InterPro:IPR016167,IPR006094,IPR036318; antiSMASH:Cluster_2.1; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_20043S TransMembrane:1 (i82-103o) AKAW2_20044A CAZy:AA3; COG:E; EggNog:ENOG410Q22J; InterPro:IPR012132,IPR036188,IPR027424,IPR000172, IPR007867; PFAM:PF00732,PF05199; SECRETED:SignalP(1-16); go_function: GO:0016614 - oxidoreductase activity, acting on CH-OH group of donors [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_20045S COG:G; EggNog:ENOG410PGRF; InterPro:IPR015943,IPR011045,IPR019405; PFAM:PF10282; SECRETED:SignalP(1-17); go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_20046A COG:K; EggNog:ENOG410Q1CX; InterPro:IPR036236,IPR013087,IPR007219; PFAM:PF00096,PF04082; TransMembrane:1 (i431-451o); go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA] AKAW2_20047A COG:S; EggNog:ENOG410PGZI; TransMembrane:6 (o20-43i50-71o83-105i117-141o161-182i203-224o) AKAW2_20049S COG:G; EggNog:ENOG410PFWR; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i90-107o127-146i158-185o191-210i217-240o246-266i341- 360o380-398i418-436o442-469i490-508o514-532i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_20050A COG:I; EggNog:ENOG410PIDF; InterPro:IPR042098,IPR003819; PFAM:PF02668; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_20051S CAZy:GH28; COG:G; EggNog:ENOG410PMNA; InterPro:IPR000743,IPR012334,IPR006626,IPR011050; PFAM:PF00295; SECRETED:SignalP(1-19); go_function: GO:0004650 - polygalacturonase activity [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_20052S COG:I; EggNog:ENOG410PW7X; InterPro:IPR006176,IPR036291,IPR029752; PFAM:PF02737; go_function: GO:0003857 - 3-hydroxyacyl-CoA dehydrogenase activity [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0006631 - fatty acid metabolic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_20053A COG:G; EggNog:ENOG410PHMC; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i71-95o110-127i139-158o164-185i197-221o227-246i289- 312o332-354i375-394o406-429i441-460o472-491i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_20054S COG:S; EggNog:ENOG410PNJC; InterPro:IPR002575; PFAM:PF01636 AKAW2_20055A COG:K; EggNog:ENOG410PHDW; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_20056S COG:I; EggNog:ENOG410PVQ7; InterPro:IPR008775; PFAM:PF05721 AKAW2_20057A COG:S; EggNog:ENOG410Q2BR; InterPro:IPR017771,IPR003607 AKAW2_20058A COG:K; EggNog:ENOG410PVKB; InterPro:IPR021858; PFAM:PF11951 AKAW2_20059A COG:S; EggNog:ENOG410PW7A; InterPro:IPR011009,IPR002575; PFAM:PF01636 AKAW2_20060S COG:S; EggNog:ENOG410PWXG AKAW2_20061S COG:S; EggNog:ENOG410PWXG AKAW2_20062A COG:S; EggNog:ENOG410PRHR; InterPro:IPR011008 AKAW2_20063S COG:S; EggNog:ENOG410PYW8; SECRETED:SignalP(1-22) AKAW2_20064S SECRETED:SignalP(1-21) AKAW2_20065S SECRETED:SignalP(1-21) AKAW2_20066A COG:S; EggNog:ENOG410PWPB; TransMembrane:1 (i158-177o) AKAW2_20067A COG:S; EggNog:ENOG410PWPB; InterPro:IPR021840; PFAM:PF11915; TransMembrane:7 (i49-70o90-110i158-183o517-535i627-645o665-685i734-757o) AKAW2_20068S SECRETED:SignalP(1-19) AKAW2_20069A COG:S; EggNog:ENOG410Q1US; InterPro:IPR037401,IPR032710; PFAM:PF12680,PF13577 AKAW2_20070A COG:S; EggNog:ENOG410PUFN; InterPro:IPR036188,IPR002938; go_function: GO:0071949 - FAD binding [Evidence IEA] AKAW2_20071S COG:G; EggNog:ENOG410PWM6; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (o36-62i74-91o103-119i131-153o187-205i232-252o264-284i304- 325o337-356i368-386o392-415i498-519o); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_20072A COG:S; EggNog:ENOG410PQUX; InterPro:IPR011008,IPR013097; PFAM:PF07876 AKAW2_20073S COG:K; EggNog:ENOG410Q25B; InterPro:IPR036864,IPR001138; PFAM:PF00172; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_20075A COG:S; EggNog:ENOG410Q1U5; InterPro:IPR007219; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA] AKAW2_20076A COG:Q; EggNog:ENOG410PJDN; InterPro:IPR001128,IPR017972,IPR002401,IPR036396; PFAM:PF00067; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_20077A COG:S; EggNog:ENOG410PHJV; InterPro:IPR022596,IPR023041; PFAM:PF11710,PF11970; TransMembrane:7 (o46-69i90-113o138-156i163-185o213-232i258-278o290-314i) AKAW2_20078A COG:S; EggNog:ENOG410PFEA AKAW2_20079A COG:B,K; EggNog:ENOG410PKX1; InterPro:IPR011257,IPR003265; PFAM:PF00730; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_process: GO:0006281 - DNA repair [Evidence IEA]; go_process: GO:0006284 - base-excision repair [Evidence IEA] AKAW2_20080A COG:E; EggNog:ENOG410PGQX; InterPro:IPR000101,IPR043137,IPR029055,IPR043138; MEROPS:MER0001629; PFAM:PF01019; TransMembrane:1 (i48-70o); go_function: GO:0036374 - glutathione hydrolase activity [Evidence IEA]; go_process: GO:0006751 - glutathione catabolic process [Evidence IEA] AKAW2_20081A COG:S; EggNog:ENOG410Q1WQ; InterPro:IPR036864,IPR021858,IPR001138; PFAM:PF00172; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_20082S COG:S; EggNog:ENOG410PWKM; InterPro:IPR036864,IPR001138; PFAM:PF00172; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_20083S COG:S; EggNog:ENOG410PKSY; TransMembrane:7 (o50-76i168-184o342-367i468-489o537-560i581-605o637-656i) AKAW2_20084A CAZy:GH92; COG:G; EggNog:ENOG410PKN0; InterPro:IPR041371,IPR014718,IPR012939,IPR008928, IPR005887; PFAM:PF17678,PF07971; SECRETED:SignalP(1-20); go_function: GO:0030246 - carbohydrate binding [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_20085A COG:G; EggNog:ENOG410QE3G; InterPro:IPR011701,IPR036259; PFAM:PF07690,PF06609; TransMembrane:14 (i84-102o122-141i153-170o176-198i210-229o241-264i294- 313o325-345i365-387o407-425i432-453o459-478i499-522o572- 592i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_20086A BUSCO:EOG09261727; COG:K; EggNog:ENOG410PGHN; InterPro:IPR001374,IPR036867,IPR034077,IPR000967, IPR034078,IPR019786; PFAM:PF01422,PF01424; go_component: GO:0005634 - nucleus [Evidence IEA]; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0003700 - DNA-binding transcription factor activity [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_20087A COG:D; EggNog:ENOG410PQGA; InterPro:IPR014898,IPR039999; PFAM:PF08790; go_function: GO:0003677 - DNA binding [Evidence IEA] AKAW2_20088A COG:O; EggNog:ENOG410PQ4I; InterPro:IPR036774,IPR017905,IPR039799; PFAM:PF04777; go_function: GO:0016971 - flavin-linked sulfhydryl oxidase activity [Evidence IEA]; go_function: GO:0016972 - thiol oxidase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_20089A COG:S; EggNog:ENOG410PJEQ; InterPro:IPR022742,IPR029058; MEROPS:MER0017242; PFAM:PF03959,PF00326,PF12146; TransMembrane:1 (o20-43i) AKAW2_20090S COG:O; EggNog:ENOG410PFUB; InterPro:IPR029055,IPR001353,IPR023333,IPR000243, IPR037559,IPR016050; MEROPS:MER0001645; PFAM:PF00227; go_component: GO:0005839 - proteasome core complex [Evidence IEA]; go_function: GO:0004298 - threonine-type endopeptidase activity [Evidence IEA]; go_process: GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process [Evidence IEA]; go_process: GO:0051603 - proteolysis involved in cellular protein catabolic process [Evidence IEA] AKAW2_20091S BUSCO:EOG09263L00; COG:S; EggNog:ENOG410PIDM; InterPro:IPR013922; go_function: GO:0019901 - protein kinase binding [Evidence IEA]; go_process: GO:0000079 - regulation of cyclin-dependent protein serine/threonine kinase activity [Evidence IEA] AKAW2_20092S COG:S; EggNog:ENOG410Q1AY; SECRETED:SignalP(1-22) AKAW2_20093A COG:S; EggNog:ENOG410PZ09 AKAW2_20094A COG:O; EggNog:ENOG410PHBA; InterPro:IPR003653,IPR038765; MEROPS:MER0064210; PFAM:PF02902; go_function: GO:0008234 - cysteine-type peptidase activity [Evidence IEA]; go_process: GO:0006508 - proteolysis [Evidence IEA] AKAW2_20095A COG:T; EggNog:ENOG410PH75; InterPro:IPR000219,IPR004148,IPR027267,IPR035899, IPR001331; PFAM:PF00621; go_component: GO:0005737 - cytoplasm [Evidence IEA]; go_function: GO:0005085 - guanyl-nucleotide exchange factor activity [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0035556 - intracellular signal transduction [Evidence IEA] AKAW2_20096S COG:B,L; EggNog:ENOG410PIET; InterPro:IPR003545,IPR000477,IPR021891,IPR043502; PFAM:PF12009; TransMembrane:1 (i613-632o); go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0003721 - telomerase RNA reverse transcriptase activity [Evidence IEA]; go_function: GO:0003964 - RNA-directed DNA polymerase activity [Evidence IEA] AKAW2_20097S COG:T; EggNog:ENOG410PGK1; InterPro:IPR035969,IPR000195; PFAM:PF00566 AKAW2_20098S COG:T; EggNog:ENOG410Q2W4; InterPro:IPR000719,IPR011009; PFAM:PF07714,PF00069; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_20099A COG:Q; EggNog:ENOG410PI0J; InterPro:IPR002347,IPR036291,IPR020904; PFAM:PF00106,PF13561,PF08659; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_20100A COG:S; EggNog:ENOG410PH0U; InterPro:IPR041694,IPR013149,IPR036291,IPR011032, IPR020843; PFAM:PF00107,PF13602,PF16884; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_20101S COG:S; EggNog:ENOG410PZ53 AKAW2_20102S COG:S; EggNog:ENOG410PJEV; InterPro:IPR029058 AKAW2_20103A BUSCO:EOG09263LP3; COG:E; EggNog:ENOG410PI50; InterPro:IPR001348,IPR013115,IPR013820,IPR015867, IPR020621,IPR018198,IPR011322; PFAM:PF01634,PF08029; go_component: GO:0005737 - cytoplasm [Evidence IEA]; go_function: GO:0000287 - magnesium ion binding [Evidence IEA]; go_function: GO:0003879 - ATP phosphoribosyltransferase activity [Evidence IEA]; go_process: GO:0000105 - histidine biosynthetic process [Evidence IEA] AKAW2_20104S COG:J; EggNog:ENOG410PQTH; InterPro:IPR012340,IPR000289,IPR028626; PFAM:PF01200; go_component: GO:0005840 - ribosome [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_process: GO:0006412 - translation [Evidence IEA] AKAW2_20105A BUSCO:EOG09260LI6; COG:L; EggNog:ENOG410PGVC; InterPro:IPR027417,IPR036678,IPR036187,IPR017261, IPR007696,IPR016151,IPR000432,IPR007695,IPR007861, IPR007860; PFAM:PF05188,PF05190,PF05192,PF00488,PF01624; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0030983 - mismatched DNA binding [Evidence IEA]; go_process: GO:0006298 - mismatch repair [Evidence IEA] AKAW2_20106A COG:S; EggNog:ENOG410PR3X AKAW2_20107A BUSCO:EOG09263G3M; COG:O; EggNog:ENOG410PGTA; InterPro:IPR001330,IPR026873,IPR008930; PFAM:PF00432; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0004663 - Rab geranylgeranyltransferase activity [Evidence IEA]; go_process: GO:0018344 - protein geranylgeranylation [Evidence IEA] AKAW2_20109S COG:T; EggNog:ENOG410QDGC; InterPro:IPR000198,IPR008936; PFAM:PF00620; TransMembrane:1 (o498-517i); go_process: GO:0007165 - signal transduction [Evidence IEA] AKAW2_20110A COG:J; EggNog:ENOG410PNYS; InterPro:IPR007023; PFAM:PF04939; go_component: GO:0005634 - nucleus [Evidence IEA]; go_process: GO:0042254 - ribosome biogenesis [Evidence IEA] AKAW2_20111S BUSCO:EOG092625U6; COG:J; EggNog:ENOG410PHXU; InterPro:IPR019368; PFAM:PF10236 AKAW2_20112A COG:S; EggNog:ENOG410PW4Z; InterPro:IPR001214,IPR011990; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_20113S COG:S; EggNog:ENOG410PPGJ AKAW2_20114S COG:S; EggNog:ENOG410PUE0; InterPro:IPR007527; go_function: GO:0008270 - zinc ion binding [Evidence IEA] AKAW2_20115A COG:Q; EggNog:ENOG410PGFN; InterPro:IPR013154,IPR013149,IPR002328,IPR036291, IPR011032,IPR020843; PFAM:PF00107,PF08240; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_20116S COG:S; EggNog:ENOG410PM07; InterPro:IPR006680,IPR032466; PFAM:PF04909; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_20117A COG:Q; EggNog:ENOG410PJ9Z; InterPro:IPR036291,IPR002347; PFAM:PF08659,PF00106,PF13561; TransMembrane:1 (o257-278i); go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_20118A COG:M; EggNog:ENOG410PJ5V; InterPro:IPR023444,IPR029065,IPR036849,IPR013342, IPR013341,IPR029017; PFAM:PF13378,PF02746; go_function: GO:0050032 - L-rhamnonate dehydratase activity [Evidence IEA] AKAW2_20119S COG:K; EggNog:ENOG410PHUR; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_20120A COG:T; EggNog:ENOG410PF80; InterPro:IPR000719,IPR011009; PFAM:PF07714,PF00069; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_20121A COG:O; EggNog:ENOG410PIWE; InterPro:IPR009060,IPR036249,IPR001012,IPR006577, IPR029071; PFAM:PF14555,PF00789,PF13899; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_20122S COG:L; EggNog:ENOG410PHC7; InterPro:IPR036388,IPR003959,IPR027417,IPR003593, IPR036390,IPR015163,IPR016314; PFAM:PF09079,PF00004,PF13401; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA]; go_process: GO:0006270 - DNA replication initiation [Evidence IEA]; go_process: GO:0051301 - cell division [Evidence IEA] AKAW2_20123A BUSCO:EOG09261C0G; COG:T; EggNog:ENOG410PGKQ; InterPro:IPR001060,IPR027267,IPR008936,IPR000591, IPR000198,IPR031160,IPR036390; PFAM:PF00611,PF00610,PF00620; go_process: GO:0007165 - signal transduction [Evidence IEA]; go_process: GO:0035556 - intracellular signal transduction [Evidence IEA] AKAW2_20124A COG:E; EggNog:ENOG410PJCY; InterPro:IPR004840,IPR004841,IPR004762; PFAM:PF13520,PF00324; TransMembrane:12 (i86-107o113-140i161-180o192-210i222-244o264-284i305- 326o346-372i407-425o431-457i478-499o519-539i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_process: GO:0006865 - amino acid transport [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_20125A COG:A; EggNog:ENOG410PQY0; InterPro:IPR010920,IPR033871,IPR001163; PFAM:PF01423 AKAW2_20126S COG:S; EggNog:ENOG410PJ2P; InterPro:IPR036397,IPR012337,IPR002562; PFAM:PF01612; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0008408 - 3'-5' exonuclease activity [Evidence IEA]; go_process: GO:0006139 - nucleobase-containing compound metabolic process [Evidence IEA] AKAW2_20127A BUSCO:EOG092635ST; COG:O; EggNog:ENOG410PJ4X; InterPro:IPR001841,IPR017907,IPR006845,IPR013083; PFAM:PF13923,PF14634,PF04757,PF13920,PF14447, PF00097,PF13445,PF13639; TransMembrane:2 (o198-216i237-256o) AKAW2_20128S COG:U; EggNog:ENOG410PIWD; InterPro:IPR004342; PFAM:PF03124; TransMembrane:5 (o20-41i66-87o107-123i326-342o348-367i); go_component: GO:0016021 - integral component of membrane [Evidence IEA] AKAW2_20129A COG:S; EggNog:ENOG410PMZW; SECRETED:SignalP(1-33); TransMembrane:1 (n17-28c33/34o127-149i) AKAW2_20130A COG:S; EggNog:ENOG410PQNX; InterPro:IPR037654; SECRETED:SignalP(1-18); TransMembrane:1 (n3-13c18/19o241-265i); go_process: GO:0006078 - (1->6)-beta-D-glucan biosynthetic process [Evidence IEA]; go_process: GO:0009272 - fungal-type cell wall biogenesis [Evidence IEA] AKAW2_20131S COG:S; EggNog:ENOG410PQWB; InterPro:IPR019186; PFAM:PF09805 AKAW2_20132A BUSCO:EOG09264XUV; COG:Z; EggNog:ENOG410PNPX; InterPro:IPR000533; PFAM:PF12718 AKAW2_20133S COG:S; EggNog:ENOG410PQ8N AKAW2_20134S COG:M; EggNog:ENOG410PFZI; InterPro:IPR029063; PFAM:PF02353,PF08241,PF13649,PF13489; TransMembrane:2 (o53-71i78-100o) AKAW2_20135S COG:K; EggNog:ENOG410PKBD; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_20136A COG:G; EggNog:ENOG410Q2VM; InterPro:IPR011701,IPR036259; PFAM:PF07690; TransMembrane:7 (o14-34i88-107o127-147i168-187o193-214i226-248o260-281i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_20137A COG:G; EggNog:ENOG410Q2VM; InterPro:IPR020846,IPR011701,IPR036259; TransMembrane:2 (i61-78o98-117i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_20138A COG:Q; EggNog:ENOG410PF88; InterPro:IPR000269,IPR015798,IPR016182,IPR036460; PFAM:PF01179; go_function: GO:0005507 - copper ion binding [Evidence IEA]; go_function: GO:0008131 - primary amine oxidase activity [Evidence IEA]; go_function: GO:0048038 - quinone binding [Evidence IEA]; go_process: GO:0009308 - amine metabolic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_20139S COG:K; EggNog:ENOG410PSGR; InterPro:IPR036864,IPR021858,IPR001138; PFAM:PF00172,PF11951; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_20140A COG:S; EggNog:ENOG410PJ9U; InterPro:IPR010482,IPR006614; PFAM:PF06398; TransMembrane:3 (i84-109o115-134i213-234o); go_component: GO:0016021 - integral component of membrane [Evidence IEA] AKAW2_20141S BUSCO:EOG09265M8S; COG:U; EggNog:ENOG410PQ6Q; InterPro:IPR036869,IPR005341; PFAM:PF03656; go_component: GO:0005744 - TIM23 mitochondrial import inner membrane translocase complex [Evidence IEA]; go_process: GO:0030150 - protein import into mitochondrial matrix [Evidence IEA] AKAW2_20142S COG:C; EggNog:ENOG410PKGN; InterPro:IPR023210,IPR036812; PFAM:PF00248 AKAW2_20143A COG:L; EggNog:ENOG410PJHK; InterPro:IPR002058,IPR002934,IPR043519; PFAM:PF03828,PF01909; go_function: GO:0016779 - nucleotidyltransferase activity [Evidence IEA] AKAW2_20144A COG:S; EggNog:ENOG410PMWI; InterPro:IPR011057,IPR006913; PFAM:PF04828; go_function: GO:0016846 - carbon-sulfur lyase activity [Evidence IEA] AKAW2_20145A BUSCO:EOG0926195C; COG:O; EggNog:ENOG410PG93; InterPro:IPR026874,IPR036607,IPR028146,IPR036055, IPR039794,IPR009011; PFAM:PF13015,PF07915; SECRETED:SignalP(1-22); go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0006491 - N-glycan processing [Evidence IEA] AKAW2_20146S COG:S; EggNog:ENOG410PN59; InterPro:IPR006735,IPR027799; PFAM:PF04641; go_process: GO:1902979 - mitotic DNA replication termination [Evidence IEA] AKAW2_20147A COG:S; EggNog:ENOG410PT3P; InterPro:IPR018305; PFAM:PF10501; go_component: GO:0005739 - mitochondrion [Evidence IEA] AKAW2_20148A COG:I; EggNog:ENOG410PHTR; InterPro:IPR016039,IPR020613,IPR020610,IPR020617, IPR020616,IPR020615,IPR002155; PFAM:PF00108,PF02803; go_function: GO:0016746 - transferase activity, transferring acyl groups [Evidence IEA]; go_function: GO:0016747 - transferase activity, transferring acyl groups other than amino-acyl groups [Evidence IEA] AKAW2_20149A COG:S; EggNog:ENOG410PS0A AKAW2_20150S COG:Q; EggNog:ENOG410PNMS; InterPro:IPR036291,IPR002347; PFAM:PF08659,PF00106,PF13561; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_20151S COG:E; EggNog:ENOG410PG9I; InterPro:IPR006219,IPR013785,IPR006218; PFAM:PF00793; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0003849 - 3-deoxy-7-phosphoheptulonate synthase activity [Evidence IEA]; go_process: GO:0009058 - biosynthetic process [Evidence IEA]; go_process: GO:0009073 - aromatic amino acid family biosynthetic process [Evidence IEA] AKAW2_20152A COG:S; EggNog:ENOG410PRFB; InterPro:IPR029208; PFAM:PF14880; TransMembrane:1 (i100-120o) AKAW2_20153S COG:S; EggNog:ENOG410PRC2; InterPro:IPR018858; PFAM:PF10454 AKAW2_20154A COG:G; EggNog:ENOG410PIP7; InterPro:IPR001312,IPR022673,IPR022672,IPR043129; PFAM:PF00349,PF03727; TransMembrane:1 (o15-33i); go_function: GO:0004396 - hexokinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0005536 - glucose binding [Evidence IEA]; go_function: GO:0016773 - phosphotransferase activity, alcohol group as acceptor [Evidence IEA]; go_process: GO:0001678 - cellular glucose homeostasis [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_20155S COG:S; EggNog:ENOG410PTAC; InterPro:IPR021331; PFAM:PF11160 AKAW2_20156S COG:S; EggNog:ENOG410PJCV; InterPro:IPR029058; SECRETED:SignalP(1-22) AKAW2_20157S COG:S; EggNog:ENOG410Q2VP; InterPro:IPR039535,IPR011047; PFAM:PF05935,PF14269; SECRETED:SignalP(1-21); TransMembrane:1 (n2-12c21/22o572-596i) AKAW2_20158A COG:S; EggNog:ENOG410PZE3 AKAW2_20159S BUSCO:EOG09264O6J; COG:F; EggNog:ENOG410PG3G; InterPro:IPR000850,IPR027417,IPR033690,IPR006266; PFAM:PF00406,PF13238,PF13207; go_function: GO:0004127 - cytidylate kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0009041 - uridylate kinase activity [Evidence IEA]; go_function: GO:0019205 - nucleobase-containing compound kinase activity [Evidence IEA]; go_process: GO:0006139 - nucleobase-containing compound metabolic process [Evidence IEA]; go_process: GO:0006207 - 'de novo' pyrimidine nucleobase biosynthetic process [Evidence IEA]; go_process: GO:0006221 - pyrimidine nucleotide biosynthetic process [Evidence IEA] AKAW2_20160A COG:J; EggNog:ENOG410PFV2; InterPro:IPR040750,IPR027528,IPR000717; PFAM:PF18005,PF01399; go_component: GO:0005737 - cytoplasm [Evidence IEA]; go_component: GO:0005852 - eukaryotic translation initiation factor 3 complex [Evidence IEA]; go_function: GO:0003743 - translation initiation factor activity [Evidence IEA] AKAW2_20161A COG:S; EggNog:ENOG410PS2K; SECRETED:SignalP(1-17) AKAW2_20163S COG:S; EggNog:ENOG410PX6T; InterPro:IPR029069,IPR006683; PFAM:PF03061 AKAW2_20162A COG:S; EggNog:ENOG410PY40; InterPro:IPR029069,IPR042171; PFAM:PF13622 AKAW2_20164A CAZy:GT20; COG:G; EggNog:ENOG410PH2A; InterPro:IPR001830,IPR003337,IPR006379,IPR036412, IPR023214; PFAM:PF00982,PF02358; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_process: GO:0005992 - trehalose biosynthetic process [Evidence IEA] AKAW2_20165S COG:S; EggNog:ENOG410PPJB; InterPro:IPR018865; PFAM:PF10494 AKAW2_20166S COG:S; EggNog:ENOG410PRIG; InterPro:IPR024500; PFAM:PF11274 AKAW2_20167A COG:K; EggNog:ENOG410PIHY; InterPro:IPR036236,IPR013087; SECRETED:SignalP(1-18) AKAW2_20169S COG:S; EggNog:ENOG410PIM8; TransMembrane:4 (i145-171o191-215i227-251o292-319i) AKAW2_20170A BUSCO:EOG09260WU6; COG:L; EggNog:ENOG410PFHS; InterPro:IPR022816; PFAM:PF05786; go_component: GO:0000796 - condensin complex [Evidence IEA]; go_process: GO:0007076 - mitotic chromosome condensation [Evidence IEA] AKAW2_20172S COG:P; EggNog:ENOG410PHZ1; InterPro:IPR004837; PFAM:PF01699; TransMembrane:12 (n28-39c47/48o111-130i142-161o181-202i214-232o244-263i752- 773o785-806i818-839o851-871i883-912o932-953i965-983o); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_20171A COG:Z; EggNog:ENOG410Q4IW; InterPro:IPR011992,IPR013182,IPR002048,IPR003124, IPR000261; PFAM:PF08226,PF12763; go_function: GO:0003779 - actin binding [Evidence IEA]; go_function: GO:0005509 - calcium ion binding [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_20173A BUSCO:EOG0926591L; COG:K; EggNog:ENOG410PQZG; InterPro:IPR036603,IPR037685,IPR009025,IPR008193; PFAM:PF01193,PF13656; go_component: GO:0005665 - RNA polymerase II, core complex [Evidence IEA]; go_function: GO:0001055 - RNA polymerase II activity [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0003899 - DNA-directed 5'-3' RNA polymerase activity [Evidence IEA]; go_function: GO:0046983 - protein dimerization activity [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006366 - transcription by RNA polymerase II [Evidence IEA] AKAW2_20174A COG:S; EggNog:ENOG410PM4S AKAW2_20175A COG:L; EggNog:ENOG410PM3S; InterPro:IPR032675,IPR006553 AKAW2_20176S BUSCO:EOG09260NNR; COG:L; EggNog:ENOG410PHZD; InterPro:IPR001841,IPR027417,IPR017907,IPR000330, IPR038718,IPR018957,IPR001650,IPR014001,IPR013083; PFAM:PF00176,PF00097,PF00271; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0046872 - metal ion binding [Evidence IEA] AKAW2_20177S COG:S; EggNog:ENOG410PJA6; InterPro:IPR000008,IPR035892; PFAM:PF00168 AKAW2_20178S COG:T; EggNog:ENOG410PGGG; InterPro:IPR001164,IPR027267,IPR038508,IPR011993, IPR001849,IPR037278; PFAM:PF01412,PF00169,PF16746; go_function: GO:0005096 - GTPase activator activity [Evidence IEA] AKAW2_20180S COG:A; EggNog:ENOG410QE4I; InterPro:IPR000504,IPR007275,IPR035979,IPR012677; PFAM:PF04146,PF00076; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0003723 - RNA binding [Evidence IEA] AKAW2_20181S COG:S; EggNog:ENOG410PPBN AKAW2_20182A COG:T; EggNog:ENOG410PHQ4; InterPro:IPR001263,IPR015433,IPR016024,IPR036940, IPR018936,IPR042236,IPR011009,IPR000403; PFAM:PF00454,PF00613; go_function: GO:0016301 - kinase activity [Evidence IEA]; go_process: GO:0046854 - phosphatidylinositol phosphorylation [Evidence IEA]; go_process: GO:0048015 - phosphatidylinositol-mediated signaling [Evidence IEA] AKAW2_20183S COG:D; EggNog:ENOG410PFKJ; InterPro:IPR017441,IPR008271,IPR000719,IPR011009; PFAM:PF07714,PF00069; TransMembrane:1 (i224-243o); go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_20184S COG:Q; EggNog:ENOG410PFY8; InterPro:IPR001128,IPR002403,IPR017972,IPR036396; PFAM:PF00067; TransMembrane:2 (o20-41i53-70o); go_function: GO:0004497 - monooxygenase activity [Evidence IEA]; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_20185A COG:S; EggNog:ENOG410PT9D; InterPro:IPR019083,IPR039603; PFAM:PF09597 AKAW2_20186S COG:D; EggNog:ENOG410PFPZ; InterPro:IPR017441,IPR008271,IPR037770,IPR000719, IPR011009; PFAM:PF07714,PF00069; go_component: GO:0005675 - transcription factor TFIIH holo complex [Evidence IEA]; go_component: GO:0070985 - transcription factor TFIIK complex [Evidence IEA]; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0008353 - RNA polymerase II CTD heptapeptide repeat kinase activity [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_20187S BUSCO:EOG092631IR; COG:Z; EggNog:ENOG410PGWU; InterPro:IPR019821,IPR036961,IPR027417,IPR027640, IPR001752; PFAM:PF16796,PF00225; go_function: GO:0003777 - microtubule motor activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0008017 - microtubule binding [Evidence IEA]; go_process: GO:0007018 - microtubule-based movement [Evidence IEA] AKAW2_20188A BUSCO:EOG09261G92; COG:I; EggNog:ENOG410PF9N; InterPro:IPR007130; PFAM:PF03982; TransMembrane:2 (i84-110o116-134i); go_function: GO:0016747 - transferase activity, transferring acyl groups other than amino-acyl groups [Evidence IEA] AKAW2_20189A COG:A; EggNog:ENOG410PPE4; InterPro:IPR000467; PFAM:PF01585; go_function: GO:0003676 - nucleic acid binding [Evidence IEA] AKAW2_20190S COG:I; EggNog:ENOG410PGU5; InterPro:IPR002013,IPR005135,IPR000300,IPR036691; PFAM:PF03372,PF02383; go_function: GO:0042578 - phosphoric ester hydrolase activity [Evidence IEA]; go_process: GO:0046856 - phosphatidylinositol dephosphorylation [Evidence IEA] AKAW2_20191A COG:S; EggNog:ENOG410PQ4V AKAW2_20192A BUSCO:EOG09263R62; COG:S; EggNog:ENOG410PM7U; InterPro:IPR011990,IPR019734,IPR013026,IPR039856; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_20193S COG:U; EggNog:ENOG410PF8I; InterPro:IPR016024,IPR002553,IPR017105; PFAM:PF01602; go_component: GO:0030117 - membrane coat [Evidence IEA]; go_component: GO:0030123 - AP-3 adaptor complex [Evidence IEA]; go_process: GO:0006886 - intracellular protein transport [Evidence IEA]; go_process: GO:0015031 - protein transport [Evidence IEA]; go_process: GO:0016192 - vesicle-mediated transport [Evidence IEA] AKAW2_20194A COG:S; EggNog:ENOG410PTK3; InterPro:IPR010580; PFAM:PF06624; TransMembrane:1 (i42-63o); go_component: GO:0005783 - endoplasmic reticulum [Evidence IEA] AKAW2_20195S COG:S; EggNog:ENOG410PJYT; InterPro:IPR029060,IPR039436,IPR026832; PFAM:PF12813 AKAW2_20196A BUSCO:EOG09260SJV; COG:S; EggNog:ENOG410PI1Y; InterPro:IPR007319,IPR019775,IPR015943,IPR011047, IPR001680,IPR017986; PFAM:PF04192,PF00400; go_component: GO:0032040 - small-subunit processome [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0006364 - rRNA processing [Evidence IEA] AKAW2_20197S BUSCO:EOG09260FMW; COG:Z; EggNog:ENOG410PF91; InterPro:IPR000560,IPR037446,IPR040557,IPR013651, IPR029033; PFAM:PF00328,PF18086,PF08443; go_function: GO:0000829 - inositol heptakisphosphate kinase activity [Evidence IEA] AKAW2_20198S COG:S; EggNog:ENOG410PJ1H; InterPro:IPR017438,IPR001206,IPR016064; PFAM:PF00781; go_function: GO:0003951 - NAD+ kinase activity [Evidence IEA]; go_function: GO:0016301 - kinase activity [Evidence IEA] AKAW2_20199S COG:O; EggNog:ENOG410QDRJ; InterPro:IPR007751,IPR016445,IPR029058 AKAW2_20200A COG:G; EggNog:ENOG410PH2U; InterPro:IPR000760,IPR020583,IPR020550,IPR033942; PFAM:PF00459; go_function: GO:0008934 - inositol monophosphate 1-phosphatase activity [Evidence IEA]; go_process: GO:0046854 - phosphatidylinositol phosphorylation [Evidence IEA]; go_process: GO:0046855 - inositol phosphate dephosphorylation [Evidence IEA] AKAW2_20201S COG:K; EggNog:ENOG410PJN7; InterPro:IPR008851,IPR011039; go_component: GO:0005634 - nucleus [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_process: GO:0006367 - transcription initiation from RNA polymerase II promoter [Evidence IEA]; go_process: GO:0032968 - positive regulation of transcription elongation from RNA polymerase II promoter [Evidence IEA] AKAW2_20202A COG:I; EggNog:ENOG410Q0WA; InterPro:IPR032088,IPR003965,IPR041099,IPR039569, IPR001227,IPR014043,IPR002539,IPR040883,IPR016452, IPR016035,IPR029069,IPR013785,IPR013565; PFAM:PF17951,PF16073,PF13452,PF17828,PF01575, PF08354,PF00698; go_component: GO:0005835 - fatty acid synthase complex [Evidence IEA]; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0004312 - fatty acid synthase activity [Evidence IEA]; go_function: GO:0004313 - [acyl-carrier-protein] S-acetyltransferase activity [Evidence IEA]; go_function: GO:0004314 - [acyl-carrier-protein] S-malonyltransferase activity [Evidence IEA]; go_function: GO:0004317 - 3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity [Evidence IEA]; go_function: GO:0004318 - enoyl-[acyl-carrier-protein] reductase (NADH) activity [Evidence IEA]; go_function: GO:0016740 - transferase activity [Evidence IEA]; go_process: GO:0006633 - fatty acid biosynthetic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_20203S COG:I; EggNog:ENOG410PFY5; InterPro:IPR037143,IPR002582,IPR016035,IPR009081, IPR041550,IPR004568,IPR036291,IPR018201,IPR026025, IPR016039,IPR002347,IPR014030,IPR014031,IPR040899, IPR008278; PFAM:PF01648,PF00109,PF02801,PF18325,PF18314, PF00106; go_component: GO:0005835 - fatty acid synthase complex [Evidence IEA]; go_function: GO:0000287 - magnesium ion binding [Evidence IEA]; go_function: GO:0004312 - fatty acid synthase activity [Evidence IEA]; go_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein] synthase activity [Evidence IEA]; go_function: GO:0004316 - 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity [Evidence IEA]; go_function: GO:0008897 - holo-[acyl-carrier-protein] synthase activity [Evidence IEA]; go_function: GO:0016746 - transferase activity, transferring acyl groups [Evidence IEA]; go_process: GO:0006633 - fatty acid biosynthetic process [Evidence IEA]; go_process: GO:0042759 - long-chain fatty acid biosynthetic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_20204A BUSCO:EOG09261H5E; COG:J; EggNog:ENOG410PFUI; InterPro:IPR042296,IPR002905,IPR029063; PFAM:PF02005; go_function: GO:0003723 - RNA binding [Evidence IEA]; go_function: GO:0004809 - tRNA (guanine-N2-)-methyltransferase activity [Evidence IEA]; go_process: GO:0008033 - tRNA processing [Evidence IEA] AKAW2_20205A COG:S; EggNog:ENOG410PPQ0; InterPro:IPR012472,IPR034804,IPR039960; PFAM:PF07950; TransMembrane:5 (i92-112o132-149i184-202o231-254i289-312o); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0032592 - integral component of mitochondrial membrane [Evidence IEA]; go_process: GO:0055088 - lipid homeostasis [Evidence IEA] AKAW2_20206S COG:S; EggNog:ENOG410PPZX; InterPro:IPR036236,IPR013087 AKAW2_20207A COG:C; EggNog:ENOG410PGHC; InterPro:IPR029061,IPR027110,IPR033248,IPR009014, IPR005475; PFAM:PF02779,PF02780; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0004739 - pyruvate dehydrogenase (acetyl-transferring) activity [Evidence IEA]; go_process: GO:0006086 - acetyl-CoA biosynthetic process from pyruvate [Evidence IEA] AKAW2_20208S COG:F; EggNog:ENOG410PHZS; InterPro:IPR029052,IPR014485,IPR006179,IPR004843, IPR041823,IPR036907; PFAM:PF00149; SECRETED:SignalP(1-30); go_function: GO:0016787 - hydrolase activity [Evidence IEA]; go_process: GO:0009166 - nucleotide catabolic process [Evidence IEA] AKAW2_20209A COG:C,K; EggNog:ENOG410PGVI; InterPro:IPR013149,IPR011032,IPR020843,IPR036291; PFAM:PF00107; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_20210S BUSCO:EOG09262UAS; COG:J; EggNog:ENOG410PGBS; InterPro:IPR023631,IPR000120,IPR020556,IPR004412, IPR036928; PFAM:PF01425; go_component: GO:0030956 - glutamyl-tRNA(Gln) amidotransferase complex [Evidence IEA]; go_function: GO:0016787 - hydrolase activity [Evidence IEA]; go_function: GO:0050567 - glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity [Evidence IEA]; go_process: GO:0006412 - translation [Evidence IEA] AKAW2_20211A BUSCO:EOG09262X7T; COG:B,K; EggNog:ENOG410PGAS; InterPro:IPR037353,IPR001870,IPR003877,IPR013320; go_component: GO:0048188 - Set1C/COMPASS complex [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0051568 - histone H3-K4 methylation [Evidence IEA] AKAW2_20212S BUSCO:EOG09263KZJ; COG:W; EggNog:ENOG410PGSF; InterPro:IPR007955; PFAM:PF05291 AKAW2_20213S COG:K; EggNog:ENOG410PPY0; InterPro:IPR004827; PFAM:PF00170,PF07716; go_function: GO:0003700 - DNA-binding transcription factor activity [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_20214S BUSCO:EOG092656CM; COG:U; EggNog:ENOG410PH3M AKAW2_20215S COG:S; EggNog:ENOG410PM9T; InterPro:IPR036864,IPR001138; PFAM:PF00172; TransMembrane:2 (o260-280i570-587o); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_20216S COG:C; EggNog:ENOG410PGYY; InterPro:IPR012791,IPR037171,IPR014388,IPR004165; PFAM:PF01144; go_function: GO:0008410 - CoA-transferase activity [Evidence IEA]; go_process: GO:0046952 - ketone body catabolic process [Evidence IEA] AKAW2_20217A COG:S; EggNog:ENOG410PI39; SECRETED:SignalP(1-22) AKAW2_20218A COG:G; EggNog:ENOG410PFHA; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690,PF00083; TransMembrane:10 (i46-66o72-95i102-119o125-146i167-189o209-229i282-307o319- 338i359-380o435-458i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_20219A COG:Q; EggNog:ENOG410PFCN; InterPro:IPR001128,IPR002403,IPR036396; PFAM:PF00067; go_function: GO:0004497 - monooxygenase activity [Evidence IEA]; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_20220S COG:C; EggNog:ENOG410PK92; InterPro:IPR001834,IPR008333,IPR001433,IPR001199, IPR017927,IPR001709,IPR036400,IPR018506,IPR017938, IPR039261; PFAM:PF00173,PF00175,PF00970; TransMembrane:2 (i125-143o175-194i); go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_20222S COG:K; EggNog:ENOG410PG1C; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_20223S COG:K; EggNog:ENOG410PG1C AKAW2_20224S COG:G; EggNog:ENOG410PWGK; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i54-75o87-106i118-136o142-165i177-199o211-238i278- 300o320-341i362-381o387-407i419-443o455-477i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_20225S COG:E; EggNog:ENOG410PK8K; InterPro:IPR036412,IPR006384,IPR023214; PFAM:PF06888,PF12710; go_function: GO:0016791 - phosphatase activity [Evidence IEA] AKAW2_20226S COG:S; EggNog:ENOG410PTE3 AKAW2_20227S COG:S; EggNog:ENOG410Q2TG AKAW2_20228S COG:S; EggNog:ENOG410Q2TG AKAW2_20231S COG:G; EggNog:ENOG410PHNV; InterPro:IPR010720,IPR017853,IPR013780; PFAM:PF06964; SECRETED:SignalP(1-25); go_function: GO:0046556 - alpha-L-arabinofuranosidase activity [Evidence IEA]; go_process: GO:0046373 - L-arabinose metabolic process [Evidence IEA] AKAW2_20232S COG:E,G; EggNog:ENOG410Q2ZW; InterPro:IPR009262; PFAM:PF06027; TransMembrane:10 (i69-86o106-125i137-157o169-187i194-213o228-248i260- 280o292-311i318-338o344-363i); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_20234S COG:O; EggNog:ENOG410PHCH; InterPro:IPR033121,IPR021109,IPR001461,IPR034163; MEROPS:MER0090758; PFAM:PF00026; go_function: GO:0004190 - aspartic-type endopeptidase activity [Evidence IEA]; go_process: GO:0006508 - proteolysis [Evidence IEA] AKAW2_20235S COG:S; EggNog:ENOG410PWX7 AKAW2_20236A COG:G; EggNog:ENOG410PG9P; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i49-72o92-114i121-140o146-166i178-198o210-230i251- 274o289-306i318-338o344-367i379-402o414-433i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_20237S COG:S; EggNog:ENOG410Q22E AKAW2_20238S COG:T; EggNog:ENOG410PUMS; InterPro:IPR004254; PFAM:PF03006; TransMembrane:7 (i92-113o125-146i158-180o192-209i221-243o255-273i294- 314o); go_component: GO:0016021 - integral component of membrane [Evidence IEA] AKAW2_20239S COG:S; EggNog:ENOG410PXQI; InterPro:IPR012942; PFAM:PF07985 AKAW2_20240S COG:S; EggNog:ENOG410Q2WI; InterPro:IPR032675 AKAW2_20241A COG:G; EggNog:ENOG410PIMJ; InterPro:IPR036259; TransMembrane:2 (i18-40o52-76i) AKAW2_20242A TransMembrane:5 (o6-24i36-53o59-83i151-173o185-205i) AKAW2_20243S COG:Q; EggNog:ENOG410PGYE; InterPro:IPR001128,IPR002401,IPR036396; PFAM:PF00067; TransMembrane:1 (o6-22i); go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_20244A COG:I; EggNog:ENOG410PJF0; InterPro:IPR029154,IPR015815,IPR036291,IPR006115, IPR008927,IPR013328; PFAM:PF03807,PF03446,PF14833,PF01488; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0050661 - NADP binding [Evidence IEA]; go_function: GO:0051287 - NAD binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_20245S COG:S; EggNog:ENOG410Q1GI AKAW2_20246S SECRETED:SignalP(1-20) AKAW2_20247S COG:S; EggNog:ENOG410PX9N; InterPro:IPR023393 AKAW2_20248S COG:S; EggNog:ENOG410PIDQ AKAW2_20249S COG:S; EggNog:ENOG410PV64; InterPro:IPR016166,IPR006094,IPR036318; PFAM:PF01565; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_function: GO:0071949 - FAD binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_20250S COG:S; EggNog:ENOG410PV64 AKAW2_20251S COG:S; EggNog:ENOG410PV64; InterPro:IPR012951; PFAM:PF08031; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_20254A COG:Q; EggNog:ENOG410PU77; InterPro:IPR002402,IPR002974,IPR036396,IPR017972, IPR001128; PFAM:PF00067; TransMembrane:1 (o6-27i); go_function: GO:0004497 - monooxygenase activity [Evidence IEA]; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0016712 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_20255A COG:S; EggNog:ENOG410Q25R AKAW2_20256A COG:S; EggNog:ENOG410PRVU AKAW2_20257A COG:S; EggNog:ENOG410PNBI; InterPro:IPR038656,IPR000250,IPR013320; MEROPS:MER0001321; PFAM:PF01828; SECRETED:SignalP(1-18); go_function: GO:0004190 - aspartic-type endopeptidase activity [Evidence IEA]; go_process: GO:0006508 - proteolysis [Evidence IEA] AKAW2_20258A COG:S; EggNog:ENOG410PVXT; InterPro:IPR038903; SECRETED:SignalP(1-19); go_component: GO:0005576 - extracellular region [Evidence IEA]; go_function: GO:0019863 - IgE binding [Evidence IEA] AKAW2_20259A COG:U; EggNog:ENOG410PJU3; InterPro:IPR027245,IPR036286,IPR015927,IPR001733, IPR019756; MEROPS:MER0000600; PFAM:PF00717; TransMembrane:3 (o12-29i129-145o151-167i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0004252 - serine-type endopeptidase activity [Evidence IEA]; go_function: GO:0008233 - peptidase activity [Evidence IEA]; go_process: GO:0006465 - signal peptide processing [Evidence IEA] AKAW2_20260A COG:S; EggNog:ENOG410PMT1; InterPro:IPR008441,IPR029044; PFAM:PF05704 AKAW2_20261S COG:S; EggNog:ENOG410PQ9R; InterPro:IPR005025,IPR029039; PFAM:PF03358; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA] AKAW2_20262S COG:S; EggNog:ENOG410PIV4; InterPro:IPR002937,IPR036188; PFAM:PF01593,PF13450; SECRETED:SignalP(1-20); go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_20263S COG:S; EggNog:ENOG410Q2BE; InterPro:IPR019268; PFAM:PF10042 AKAW2_20264A COG:C; EggNog:ENOG410PFYI; InterPro:IPR015590,IPR044086,IPR029510,IPR016161, IPR016162,IPR016163; PFAM:PF00171; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0016620 - oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_20265S COG:Q; EggNog:ENOG410PHRP; InterPro:IPR013154,IPR013149,IPR002328,IPR036291, IPR011032,IPR020843; PFAM:PF00107,PF08240,PF16912; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_20266A COG:K; EggNog:ENOG410PW0Q; InterPro:IPR000845,IPR035994,IPR002110,IPR036770, IPR020683; PFAM:PF01048,PF12796,PF00023,PF13857,PF13637, PF13606; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0009116 - nucleoside metabolic process [Evidence IEA] AKAW2_20268S COG:S; EggNog:ENOG410PXEU; InterPro:IPR036465 AKAW2_20271S COG:Q; EggNog:ENOG410PUDI; InterPro:IPR001128,IPR002401,IPR036396; PFAM:PF00067; TransMembrane:1 (o6-23i); go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_20272A COG:S; EggNog:ENOG410Q19Y; InterPro:IPR036864,IPR021858,IPR001138; PFAM:PF00172; TransMembrane:2 (i168-187o199-221i); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_20273S COG:S; EggNog:ENOG410PN5J; InterPro:IPR007568; PFAM:PF04479; TransMembrane:7 (o12-34i46-67o79-99i120-137o157-179i199-219o234-254i); go_component: GO:0016021 - integral component of membrane [Evidence IEA] AKAW2_20274A COG:E; EggNog:ENOG410PVQQ; InterPro:IPR015424,IPR021115,IPR002129,IPR015421; PFAM:PF00282; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0016831 - carboxy-lyase activity [Evidence IEA]; go_function: GO:0030170 - pyridoxal phosphate binding [Evidence IEA]; go_process: GO:0019752 - carboxylic acid metabolic process [Evidence IEA] AKAW2_20275S COG:P; EggNog:ENOG410QE3E; InterPro:IPR020846,IPR036259; TransMembrane:6 (i46-65o85-105i117-135o141-162i174-193o205-229i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA] AKAW2_20276S COG:P; EggNog:ENOG410QE3E; InterPro:IPR011701,IPR036259; TransMembrane:5 (n11-22c27/28o51-71i78-97o109-127i139-166o216-236i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_20277S COG:S; EggNog:ENOG410PQKM AKAW2_20278S COG:S; EggNog:ENOG410PQKM AKAW2_20279S COG:S; EggNog:ENOG410PQKM AKAW2_20280S COG:S; EggNog:ENOG410PQKM; TransMembrane:2 (i316-337o470-488i) AKAW2_20281S COG:S; EggNog:ENOG410PUN6 AKAW2_20283A COG:A; EggNog:ENOG410PIW8; InterPro:IPR027417,IPR001650,IPR014014,IPR014001, IPR011545; PFAM:PF00270,PF00271; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0004386 - helicase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA] AKAW2_20284A CAZy:GH11; COG:G; EggNog:ENOG410PK7J; InterPro:IPR001137,IPR013319,IPR033119,IPR033123, IPR018208,IPR013320; PFAM:PF00457; SECRETED:SignalP(1-18); go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_20285A COG:S; EggNog:ENOG410PPM4; TransMembrane:1 (i29-53o) AKAW2_20287S COG:G; EggNog:ENOG410PMTI; InterPro:IPR005829,IPR005828,IPR003663,IPR036259, IPR020846; PFAM:PF00083,PF07690; TransMembrane:12 (i21-45o65-85i92-110o116-139i159-181o187-208i280-300o312- 334i341-361o381-401i413-432o444-463i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_20288S COG:G; EggNog:ENOG410PI4Z; InterPro:IPR005829,IPR005828,IPR003663,IPR036259, IPR020846; PFAM:PF00083,PF07690; TransMembrane:12 (i27-44o64-88i100-118o124-146i158-177o226-245i319-341o356- 378i385-404o424-449i461-480o492-510i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_20289A CAZy:AA1; COG:Q; EggNog:ENOG410PKCR; InterPro:IPR008972,IPR011707,IPR011706,IPR033138, IPR002355,IPR001117; PFAM:PF00394,PF07731,PF07732; SECRETED:SignalP(1-17); go_function: GO:0005507 - copper ion binding [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_20290A COG:H; EggNog:ENOG410PJF6; InterPro:IPR030470,IPR039653,IPR000537; PFAM:PF01040; TransMembrane:7 (i58-77o89-107i181-200o206-224i254-272o278-297i309-332o); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0016765 - transferase activity, transferring alkyl or aryl (other than methyl) groups [Evidence IEA] AKAW2_20291A COG:S; EggNog:ENOG410PH44; InterPro:IPR001077,IPR036388,IPR016461,IPR029063, IPR036390; PFAM:PF00891; go_function: GO:0008168 - methyltransferase activity [Evidence IEA]; go_function: GO:0008171 - O-methyltransferase activity [Evidence IEA] AKAW2_20292S COG:S; EggNog:ENOG410PWZ5; TransMembrane:7 (o18-37i49-69o89-106i127-149o175-197i209-229o249-268i) AKAW2_20293A COG:S; EggNog:ENOG410PU2J AKAW2_20294S COG:S; EggNog:ENOG410Q57A; SECRETED:SignalP(1-19) AKAW2_20295S COG:S; EggNog:ENOG410PZ4W AKAW2_20296S COG:S; EggNog:ENOG410PZ4W AKAW2_20297A BUSCO:EOG09263MIB; COG:H; EggNog:ENOG410PI0Y; InterPro:IPR011060,IPR013785,IPR001852,IPR033755; PFAM:PF01680; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_process: GO:0042819 - vitamin B6 biosynthetic process [Evidence IEA]; go_process: GO:0042823 - pyridoxal phosphate biosynthetic process [Evidence IEA] AKAW2_20298S COG:E; EggNog:ENOG410PHWC; InterPro:IPR004839,IPR015424,IPR015421,IPR015422; PFAM:PF00155; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0030170 - pyridoxal phosphate binding [Evidence IEA]; go_process: GO:0009058 - biosynthetic process [Evidence IEA] AKAW2_20299A COG:K; EggNog:ENOG410PIUD; InterPro:IPR007219; PFAM:PF04082,PF00172; TransMembrane:2 (o240-258i279-298o); go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA] AKAW2_20300S COG:S; EggNog:ENOG410PPJK; InterPro:IPR003719; PFAM:PF02567; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_process: GO:0009058 - biosynthetic process [Evidence IEA] AKAW2_20301S COG:G; EggNog:ENOG410PVUG; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690,PF06609; TransMembrane:14 (i21-46o58-77i89-107o113-135i147-168o174-195i215-235o247- 265i286-305o325-347i354-372o378-398i410-431o493-512i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_20302A InterPro:IPR021833; PFAM:PF11905; TransMembrane:1 (i166-187o) AKAW2_20303A COG:S; EggNog:ENOG410Q1SN AKAW2_20304A COG:S; EggNog:ENOG410PTQZ; InterPro:IPR011021,IPR014752; PFAM:PF00339 AKAW2_20305S COG:O; EggNog:ENOG410PIYY; InterPro:IPR012317,IPR016135,IPR000608; PFAM:PF00179; go_function: GO:0003950 - NAD+ ADP-ribosyltransferase activity [Evidence IEA] AKAW2_20306A COG:S; EggNog:ENOG410PSV1 AKAW2_20307S COG:M; EggNog:ENOG410PQCH; InterPro:IPR002110,IPR036770,IPR020683; PFAM:PF12796,PF00023,PF13637,PF13606; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_20308A BUSCO:EOG092645L9; COG:L; EggNog:ENOG410PNWY; InterPro:IPR001841,IPR014857,IPR036388,IPR011513, IPR013083; PFAM:PF08746,PF07574; go_component: GO:0030915 - Smc5-Smc6 complex [Evidence IEA]; go_process: GO:0006281 - DNA repair [Evidence IEA] AKAW2_20309A COG:A; EggNog:ENOG410PHGA; InterPro:IPR000504,IPR035979,IPR012677,IPR009145, IPR000571; PFAM:PF00642; go_component: GO:0089701 - U2AF complex [Evidence IEA]; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0003723 - RNA binding [Evidence IEA]; go_function: GO:0046872 - metal ion binding [Evidence IEA]; go_process: GO:0000398 - mRNA splicing, via spliceosome [Evidence IEA] AKAW2_20310A COG:E; EggNog:ENOG410Q18Y; InterPro:IPR006076,IPR036188; PFAM:PF01266; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_20311S COG:Q; EggNog:ENOG410PNB7; InterPro:IPR036291,IPR002347,IPR020904; PFAM:PF00106,PF13561; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_20312S COG:K; EggNog:ENOG410PNSW; InterPro:IPR009072,IPR042225,IPR003958; PFAM:PF00125,PF00808; go_component: GO:0017054 - negative cofactor 2 complex [Evidence IEA]; go_function: GO:0003712 - transcription coregulator activity [Evidence IEA]; go_function: GO:0046982 - protein heterodimerization activity [Evidence IEA]; go_process: GO:0000122 - negative regulation of transcription by RNA polymerase II [Evidence IEA] AKAW2_20313A COG:E; EggNog:ENOG410PGP9; InterPro:IPR002821,IPR008040,IPR003692,IPR043129; PFAM:PF01968,PF05378,PF02538; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_20314A COG:S; EggNog:ENOG410PPIV; InterPro:IPR010730; PFAM:PF06985; antiSMASH:Cluster_2.2 AKAW2_20315A COG:S; EggNog:ENOG410PN1U; antiSMASH:Cluster_2.2 AKAW2_20316A COG:S; EggNog:ENOG410PN1U; TransMembrane:6 (o12-35i47-68o109-129i136-158o183-209i221-239o); antiSMASH:Cluster_2.2 AKAW2_20317S COG:S; EggNog:ENOG410PNRD; InterPro:IPR012312; PFAM:PF01814; antiSMASH:Cluster_2.2 AKAW2_20318A COG:G; EggNog:ENOG410PKJQ; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690,PF06609; SMCOG1005:Drug resistance transporter, EmrB/QacA; TransMembrane:14 (i54-80o92-111i123-142o148-169i181-207o213-231i243- 267o279-298i319-343o355-374i386-406o412-434i455-472o525- 544i); antiSMASH:Cluster_2.2; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_20319A CAZy:GH2; COG:G; EggNog:ENOG410PKJX; InterPro:IPR006103,IPR006102,IPR006101,IPR006104, IPR036156,IPR008979,IPR017853,IPR013783,IPR023230, IPR023232; PFAM:PF00703,PF02836,PF02837; antiSMASH:Cluster_2.2; go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_20320S TransMembrane:1 (n3-10c15/16o31-49i); antiSMASH:Cluster_2.2 AKAW2_20321S COG:I; EggNog:ENOG410PH25; InterPro:IPR000873,IPR009081,IPR036736,IPR020806, IPR011004,IPR042099; PFAM:PF00501,PF00550; TransMembrane:7 (o775-794i821-848o868-894i1047-1065o1101-1126i1324- 1357o1377-1405i); antiSMASH:Cluster_2.2; go_function: GO:0031177 - phosphopantetheine binding [Evidence IEA] AKAW2_20322A COG:S; EggNog:ENOG410Q1AX; SECRETED:SignalP(1-18); antiSMASH:Cluster_2.2 AKAW2_20323A COG:S; EggNog:ENOG410PXV2; InterPro:IPR036378,IPR000782; PFAM:PF02469; SECRETED:SignalP(1-20); antiSMASH:Cluster_2.2 AKAW2_20324S COG:G; EggNog:ENOG410PVKQ; InterPro:IPR002241,IPR041233,IPR017853,IPR013780, IPR013785; PFAM:PF17801,PF16499; SECRETED:SignalP(1-26); antiSMASH:Cluster_2.2; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_20325S COG:K; EggNog:ENOG410PUJN; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; antiSMASH:Cluster_2.2; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_20326A CAZy:GH88; COG:S; EggNog:ENOG410PJQY; InterPro:IPR008928,IPR010905; PFAM:PF07470; antiSMASH:Cluster_2.2; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_20327S COG:G; EggNog:ENOG410QDHQ; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; SMCOG1106:major facilitator transporter; TransMembrane:12 (i41-59o79-100i121-139o145-166i178-201o207-229i275- 302o314-333i345-365o371-392i404-424o436-457i); antiSMASH:Cluster_2.2; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_20328A COG:S; EggNog:ENOG410PVR4; InterPro:IPR008929; SECRETED:SignalP(1-18); antiSMASH:Cluster_2.2 AKAW2_20329S InterPro:IPR025975; PFAM:PF14099; SECRETED:SignalP(1-19); antiSMASH:Cluster_2.2 AKAW2_20330S COG:S; EggNog:ENOG410PQC7; TransMembrane:6 (n5-12c20/21o36-56i129-148o160-181i202-235o247-269i321- 344o); antiSMASH:Cluster_2.2 AKAW2_20331A COG:S; EggNog:ENOG410PM6C; InterPro:IPR002110,IPR027417,IPR007111,IPR036770, IPR020683; PFAM:PF05729,PF12796; antiSMASH:Cluster_2.2; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_20332S COG:Z; EggNog:ENOG410PFKF; InterPro:IPR004000,IPR043129; PFAM:PF00022 AKAW2_20334A COG:J; EggNog:ENOG410PPR2; InterPro:IPR006175,IPR035959; PFAM:PF01042 AKAW2_20335A COG:S; EggNog:ENOG410PX7T; TransMembrane:7 (o15-35i47-69o89-110i131-151o195-218i230-253o265-290i) AKAW2_20336S COG:C; EggNog:ENOG410PMMX; InterPro:IPR006094,IPR036318,IPR016166,IPR016167, IPR016169; PFAM:PF01565; SECRETED:SignalP(1-17); go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_function: GO:0071949 - FAD binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_20337S COG:M; EggNog:ENOG410PF7T; InterPro:IPR000845,IPR035994; PFAM:PF01048; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_process: GO:0009116 - nucleoside metabolic process [Evidence IEA] AKAW2_20338S COG:S; EggNog:ENOG410PM9S; TransMembrane:3 (o6-33i80-101o701-724i) AKAW2_20340S TransMembrane:1 (o44-62i) AKAW2_20341S COG:S; EggNog:ENOG410PTW4; TransMembrane:2 (i63-82o97-118i) AKAW2_20342S COG:S; EggNog:ENOG410PW02; InterPro:IPR021514; PFAM:PF11374; TransMembrane:3 (o69-89i101-122o527-549i) AKAW2_20343S BUSCO:EOG092657UN; COG:A; EggNog:ENOG410PG1U; InterPro:IPR036236,IPR038254,IPR019447,IPR037321; PFAM:PF10357 AKAW2_20344S COG:E; EggNog:ENOG410PV7V; InterPro:IPR028939,IPR036291,IPR000304,IPR029036, IPR008927; PFAM:PF03807,PF14748; go_function: GO:0004735 - pyrroline-5-carboxylate reductase activity [Evidence IEA]; go_process: GO:0006561 - proline biosynthetic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_20345S COG:E; EggNog:ENOG410PIS9; InterPro:IPR002872,IPR015659,IPR029041; PFAM:PF01619; go_function: GO:0004657 - proline dehydrogenase activity [Evidence IEA]; go_process: GO:0006562 - proline catabolic process [Evidence IEA] AKAW2_20346A COG:S; EggNog:ENOG410PZHV AKAW2_20347S CAZy:GH65; COG:G; EggNog:ENOG410PGGE; InterPro:IPR037018,IPR011013,IPR008928,IPR005195, IPR012341,IPR005196; PFAM:PF03636; SECRETED:SignalP(1-22); go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0030246 - carbohydrate binding [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_20348A COG:P; EggNog:ENOG410PM93; InterPro:IPR018028,IPR029062,IPR020835,IPR011614, IPR024708,IPR002226,IPR043156,IPR041399,IPR024712, IPR037060,IPR010582; PFAM:PF18011,PF00199,PF06628; go_function: GO:0004096 - catalase activity [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0006979 - response to oxidative stress [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_20349A COG:S; EggNog:ENOG410PVJ8; InterPro:IPR014710,IPR011051; SECRETED:SignalP(1-15) AKAW2_20350A COG:G; EggNog:ENOG410PW2X; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i56-75o95-114i121-140o152-170i182-205o211-230i293- 313o333-351i372-393o405-426i438-455o461-486i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_20351A COG:S; EggNog:ENOG410PP0G; InterPro:IPR006680,IPR032466,IPR032465; PFAM:PF04909; go_function: GO:0016787 - hydrolase activity [Evidence IEA]; go_function: GO:0016831 - carboxy-lyase activity [Evidence IEA] AKAW2_20352A COG:S; EggNog:ENOG410PS4G; InterPro:IPR012942; PFAM:PF07985 AKAW2_20353A COG:E,H; EggNog:ENOG410PM41; InterPro:IPR012001,IPR012000,IPR013154,IPR013149, IPR011766,IPR029061,IPR002328,IPR036291,IPR011032, IPR029035; PFAM:PF00107,PF02776,PF08240,PF00205; go_function: GO:0000287 - magnesium ion binding [Evidence IEA]; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0030976 - thiamine pyrophosphate binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_20354S COG:G; EggNog:ENOG410QDAM; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i48-76o88-105i117-134o140-163i175-199o205-229i250- 272o284-304i316-335o341-368i380-398o404-427i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_20355S COG:P; EggNog:ENOG410PFZ2; InterPro:IPR004698,IPR003689; PFAM:PF02535; TransMembrane:8 (o33-55i67-89o109-131i194-217o223-242i254-277o297-317i329- 347o); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0005385 - zinc ion transmembrane transporter activity [Evidence IEA]; go_function: GO:0046873 - metal ion transmembrane transporter activity [Evidence IEA]; go_process: GO:0030001 - metal ion transport [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA]; go_process: GO:0071577 - zinc ion transmembrane transport [Evidence IEA] AKAW2_20356A COG:S; EggNog:ENOG410Q2TK; SECRETED:SignalP(1-17) AKAW2_20357A COG:Q; EggNog:ENOG410Q21U; InterPro:IPR036291,IPR001509; PFAM:PF08659,PF01073,PF01370; go_function: GO:0003824 - catalytic activity [Evidence IEA] AKAW2_20358A COG:S; EggNog:ENOG410PSJK AKAW2_20360A COG:S; EggNog:ENOG410PWX7 AKAW2_20363A COG:E; EggNog:ENOG410PGMG; InterPro:IPR038765,IPR004134,IPR025660,IPR000169; MEROPS:MER0002481; PFAM:PF03051; go_function: GO:0008234 - cysteine-type peptidase activity [Evidence IEA]; go_process: GO:0006508 - proteolysis [Evidence IEA] AKAW2_20365A COG:S; EggNog:ENOG410PZXQ AKAW2_20366A InterPro:IPR018247,IPR002048,IPR011992; go_function: GO:0005509 - calcium ion binding [Evidence IEA] AKAW2_20367A COG:O; EggNog:ENOG410PHFF; InterPro:IPR036852,IPR015366,IPR030400; MEROPS:MER0005329; PFAM:PF09286; SECRETED:SignalP(1-18); go_function: GO:0004252 - serine-type endopeptidase activity [Evidence IEA]; go_function: GO:0008236 - serine-type peptidase activity [Evidence IEA]; go_process: GO:0006508 - proteolysis [Evidence IEA] AKAW2_20368A InterPro:IPR002919,IPR036084; MEROPS:MER0018068; PFAM:PF01826 AKAW2_20369A COG:P; EggNog:ENOG410PFMV; InterPro:IPR003020,IPR011531; TransMembrane:11 (o54-76i88-107o113-132i139-158o200-223i235-255o295- 312i434-452o458-485i505-523o529-545i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0005452 - inorganic anion exchanger activity [Evidence IEA]; go_process: GO:0006820 - anion transport [Evidence IEA] AKAW2_20370S COG:S; EggNog:ENOG410PIJB; InterPro:IPR001214; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_20371A COG:P; EggNog:ENOG410PM93; InterPro:IPR018028,IPR029062,IPR020835,IPR011614, IPR024708,IPR002226,IPR043156,IPR041399,IPR024712, IPR037060,IPR010582; PFAM:PF18011,PF00199,PF06628; SECRETED:SignalP(1-16); go_function: GO:0004096 - catalase activity [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0006979 - response to oxidative stress [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_20372S COG:C; EggNog:ENOG410PIB6; InterPro:IPR000763,IPR002016,IPR010255,IPR019794, IPR019793; PFAM:PF00141; go_function: GO:0004096 - catalase activity [Evidence IEA]; go_function: GO:0004601 - peroxidase activity [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0006979 - response to oxidative stress [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_20373S COG:Q; EggNog:ENOG410PKS9; InterPro:IPR001613,IPR036188,IPR002937; PFAM:PF13450,PF01593; SECRETED:SignalP(1-17); go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_20374S COG:S; EggNog:ENOG410PV69; InterPro:IPR010730; PFAM:PF06985 AKAW2_20375S TransMembrane:1 (i117-135o) AKAW2_20376A COG:S; EggNog:ENOG410PWQV; TransMembrane:7 (o31-51i63-87o107-130i142-168o198-219i231-254o274-296i) AKAW2_20377S COG:G; EggNog:ENOG410PMPD; InterPro:IPR015943,IPR000254,IPR035971; PFAM:PF00734; go_component: GO:0005576 - extracellular region [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_function: GO:0030248 - cellulose binding [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_20378A COG:C; EggNog:ENOG410PG98; InterPro:IPR012133,IPR037396,IPR008259,IPR013785, IPR000262; PFAM:PF01070; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0010181 - FMN binding [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_20380S COG:P; EggNog:ENOG410QE36; InterPro:IPR005829,IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i80-100o120-140i147-170o182-200i207-230o236-257i269- 288o294-318i339-362o374-395i402-420o432-455i); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_20381A CAZy:GH20; COG:G; EggNog:ENOG410PGBW; InterPro:IPR025705,IPR017853,IPR029018,IPR013320, IPR015882,IPR015883; PFAM:PF02838; SECRETED:SignalP(1-21); go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_function: GO:0004563 - beta-N-acetylhexosaminidase activity [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_20384A COG:E; EggNog:ENOG410PFIU; InterPro:IPR002293; PFAM:PF00324,PF13520; TransMembrane:11 (o48-70i82-102o177-198i205-224o244-263i284-306o326- 350i389-409o415-437i449-470o482-502i); go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_20385A COG:P; EggNog:ENOG410Q1FJ; InterPro:IPR044089,IPR002523; PFAM:PF01544; TransMembrane:2 (i301-324o336-357i); go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0015095 - magnesium ion transmembrane transporter activity [Evidence IEA]; go_function: GO:0046873 - metal ion transmembrane transporter activity [Evidence IEA]; go_process: GO:0030001 - metal ion transport [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA]; go_process: GO:1903830 - magnesium ion transmembrane transport [Evidence IEA] AKAW2_20386S COG:H; EggNog:ENOG410PMP3; InterPro:IPR002734,IPR024072; PFAM:PF01872; go_function: GO:0008703 - 5-amino-6-(5-phosphoribosylamino)uracil reductase activity [Evidence IEA]; go_process: GO:0009231 - riboflavin biosynthetic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_20387S COG:S; EggNog:ENOG410Q1KJ; InterPro:IPR032675 AKAW2_20388S COG:E; EggNog:ENOG410PFTU; InterPro:IPR021115,IPR002129,IPR010977,IPR015424, IPR015421,IPR015422; PFAM:PF00282,PF01212; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0016831 - carboxy-lyase activity [Evidence IEA]; go_function: GO:0030170 - pyridoxal phosphate binding [Evidence IEA]; go_process: GO:0006520 - cellular amino acid metabolic process [Evidence IEA]; go_process: GO:0019752 - carboxylic acid metabolic process [Evidence IEA] AKAW2_20389S InterPro:IPR007361,IPR038694 AKAW2_20391S COG:O; EggNog:ENOG410Q2F5; SECRETED:SignalP(1-18) AKAW2_20392A COG:S; EggNog:ENOG410PSA8; InterPro:IPR036864,IPR001138; PFAM:PF00172; TransMembrane:1 (o539-560i); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_20393S COG:G; EggNog:ENOG410PJ44; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (o20-48i60-83o89-109i121-142o148-169i181-205o248-270i282- 304o310-328i335-355o367-387i399-420o); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_20394A COG:O; EggNog:ENOG410PH2R; InterPro:IPR001842,IPR027268; MEROPS:MER0001400; PFAM:PF02128; go_component: GO:0005615 - extracellular space [Evidence IEA]; go_function: GO:0004222 - metalloendopeptidase activity [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA] AKAW2_20395A COG:O; EggNog:ENOG410PH2R; InterPro:IPR001842,IPR011096; PFAM:PF07504; SECRETED:SignalP(1-23); go_component: GO:0005615 - extracellular space [Evidence IEA]; go_function: GO:0004222 - metalloendopeptidase activity [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA] AKAW2_20396A COG:S; EggNog:ENOG410PQ41; InterPro:IPR018020,IPR036778; PFAM:PF09349 AKAW2_20397S COG:S; EggNog:ENOG410PJRI; InterPro:IPR029006 AKAW2_20398A BUSCO:EOG09264HU0; COG:J; EggNog:ENOG410PFSU; InterPro:IPR020103,IPR002501,IPR014780; PFAM:PF01509; go_function: GO:0003723 - RNA binding [Evidence IEA]; go_function: GO:0009982 - pseudouridine synthase activity [Evidence IEA]; go_process: GO:0001522 - pseudouridine synthesis [Evidence IEA]; go_process: GO:0006396 - RNA processing [Evidence IEA]; go_process: GO:0009451 - RNA modification [Evidence IEA] AKAW2_20399S COG:S; EggNog:ENOG410PP1X AKAW2_20400A BUSCO:EOG09265GXF; COG:A; EggNog:ENOG410PIFB; InterPro:IPR008610; PFAM:PF05890 AKAW2_20401S COG:S; EggNog:ENOG410PYE1; InterPro:IPR010730; PFAM:PF06985 AKAW2_20402S COG:S; EggNog:ENOG410PMWB; InterPro:IPR039653; TransMembrane:2 (o63-81i117-135o) AKAW2_20403A COG:G; EggNog:ENOG410QDHM; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i51-68o94-116i123-141o153-173i185-204o216-238i290- 311o331-348i355-375o381-402i414-435o447-469i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_20404A COG:S; EggNog:ENOG410PMF6; InterPro:IPR036864,IPR021858,IPR001138; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_20405A COG:G; EggNog:ENOG410PM2E; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:14 (i122-140o160-178i190-209o215-239i251-270o276-296i317- 337o349-371i392-415o427-450i457-476o482-510i522-541o584- 608i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_20406S COG:F; EggNog:ENOG410PFRT; InterPro:IPR017926,IPR029062; MEROPS:MER0043475; PFAM:PF00117 AKAW2_20407A BUSCO:EOG09264L06; COG:S; EggNog:ENOG410PQU0; InterPro:IPR008493,IPR031318; PFAM:PF05603 AKAW2_20408S COG:F; EggNog:ENOG410PGN3; InterPro:IPR031804,IPR015797,IPR000086; PFAM:PF15916,PF00293; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_20409A BUSCO:EOG092652ZZ; COG:K; EggNog:ENOG410PMVP; InterPro:IPR005570,IPR012340; PFAM:PF03870; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA] AKAW2_20410S COG:B,K; EggNog:ENOG410PJXC; InterPro:IPR008728; PFAM:PF05625; go_component: GO:0033588 - Elongator holoenzyme complex [Evidence IEA]; go_process: GO:0002098 - tRNA wobble uridine modification [Evidence IEA] AKAW2_20411A TransMembrane:1 (o6-24i) AKAW2_20412S BUSCO:EOG09263U71; COG:J; EggNog:ENOG410PN73; InterPro:IPR036167,IPR006677,IPR011856,IPR016690; PFAM:PF01974; go_component: GO:0000214 - tRNA-intron endonuclease complex [Evidence IEA]; go_function: GO:0000213 - tRNA-intron endonuclease activity [Evidence IEA]; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0004518 - nuclease activity [Evidence IEA]; go_process: GO:0000379 - tRNA-type intron splice site recognition and cleavage [Evidence IEA]; go_process: GO:0006388 - tRNA splicing, via endonucleolytic cleavage and ligation [Evidence IEA] AKAW2_20413A BUSCO:EOG092644N1; COG:A; EggNog:ENOG410PP39; InterPro:IPR016848,IPR036980,IPR023538,IPR023534, IPR002730; PFAM:PF01868; go_component: GO:0030677 - ribonuclease P complex [Evidence IEA]; go_function: GO:0003723 - RNA binding [Evidence IEA]; go_function: GO:0004526 - ribonuclease P activity [Evidence IEA]; go_function: GO:0004540 - ribonuclease activity [Evidence IEA]; go_process: GO:0001682 - tRNA 5'-leader removal [Evidence IEA]; go_process: GO:0006396 - RNA processing [Evidence IEA]; go_process: GO:0008033 - tRNA processing [Evidence IEA] AKAW2_20414S COG:Q; EggNog:ENOG410PP6F; InterPro:IPR026992,IPR027443,IPR005123; PFAM:PF03171,PF14226; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_20415A COG:O; EggNog:ENOG410PUH6; InterPro:IPR027417,IPR003593,IPR003959; PFAM:PF00004; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA] AKAW2_20416S COG:S; EggNog:ENOG410PXGR; TransMembrane:2 (i173-188o208-229i) AKAW2_20417A COG:S; EggNog:ENOG410PRFP; InterPro:IPR012337,IPR036397,IPR002156; PFAM:PF00075; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0004523 - RNA-DNA hybrid ribonuclease activity [Evidence IEA] AKAW2_20418A COG:S; EggNog:ENOG410PQ3Y AKAW2_20419A BUSCO:EOG09265I60; COG:W; EggNog:ENOG410PPE1; InterPro:IPR011171,IPR029006,IPR002108; PFAM:PF00241; go_function: GO:0003779 - actin binding [Evidence IEA]; go_function: GO:0071933 - Arp2/3 complex binding [Evidence IEA]; go_process: GO:0034316 - negative regulation of Arp2/3 complex-mediated actin nucleation [Evidence IEA] AKAW2_20420S COG:E,H; EggNog:ENOG410QD6N; InterPro:IPR001453,IPR036425; PFAM:PF00994 AKAW2_20421A COG:S; EggNog:ENOG410PGD3; InterPro:IPR005225,IPR001806,IPR027417,IPR020849; PFAM:PF00025,PF08477,PF00071; go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0003924 - GTPase activity [Evidence IEA]; go_function: GO:0005525 - GTP binding [Evidence IEA]; go_process: GO:0007165 - signal transduction [Evidence IEA] AKAW2_20422A COG:Q; EggNog:ENOG410Q1SF; InterPro:IPR042098,IPR007817 AKAW2_20423A COG:Q; EggNog:ENOG410PGRP; InterPro:IPR007817; PFAM:PF05141 AKAW2_20424A COG:Q; EggNog:ENOG410QED2; InterPro:IPR002347,IPR036291,IPR020904; PFAM:PF00106,PF13561,PF08659; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_20425S COG:S; EggNog:ENOG410PQIW; TransMembrane:7 (o25-46i58-82o102-123i135-157o181-202i214-234o254-273i) AKAW2_20426A COG:K; EggNog:ENOG410PMWU; InterPro:IPR039355,IPR000679,IPR013088; PFAM:PF00320; go_function: GO:0003700 - DNA-binding transcription factor activity [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_function: GO:0043565 - sequence-specific DNA binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA]; go_process: GO:0006357 - regulation of transcription by RNA polymerase II [Evidence IEA] AKAW2_20427A COG:U; EggNog:ENOG410PPSS; InterPro:IPR013714; PFAM:PF08507; TransMembrane:4 (i7-27o33-53i65-86o92-111i) AKAW2_20428A COG:S; EggNog:ENOG410PTGR; InterPro:IPR011257; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_process: GO:0006281 - DNA repair [Evidence IEA] AKAW2_20429A COG:E; EggNog:ENOG410PH6Z; InterPro:IPR023209,IPR006076,IPR006181; PFAM:PF01266; go_function: GO:0003884 - D-amino-acid oxidase activity [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0071949 - FAD binding [Evidence IEA]; go_process: GO:0046416 - D-amino acid metabolic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_20430S COG:O; EggNog:ENOG410PSYG; InterPro:IPR003323,IPR038765; MEROPS:MER0139942; PFAM:PF02338 AKAW2_20431A COG:S; EggNog:ENOG410PK88; InterPro:IPR005330; PFAM:PF03707; TransMembrane:7 (o20-40i52-74o89-114i121-142o154-180i192-215o235-257i) AKAW2_20432A COG:O; EggNog:ENOG410PQT5; InterPro:IPR036249,IPR013766,IPR017937; PFAM:PF00085 AKAW2_20433A COG:S; EggNog:ENOG410PJBI AKAW2_20434S COG:U; EggNog:ENOG410PFIJ; InterPro:IPR016024,IPR011989,IPR013041,IPR002553, IPR008152,IPR008153,IPR017107; PFAM:PF01602,PF02883; go_component: GO:0005794 - Golgi apparatus [Evidence IEA]; go_component: GO:0030117 - membrane coat [Evidence IEA]; go_component: GO:0030121 - AP-1 adaptor complex [Evidence IEA]; go_process: GO:0006886 - intracellular protein transport [Evidence IEA]; go_process: GO:0016192 - vesicle-mediated transport [Evidence IEA] AKAW2_20435S COG:K; EggNog:ENOG410PJGV; InterPro:IPR003958,IPR009072,IPR003956,IPR027113; PFAM:PF00125,PF00808; go_component: GO:0005634 - nucleus [Evidence IEA]; go_component: GO:0016602 - CCAAT-binding factor complex [Evidence IEA]; go_function: GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0043565 - sequence-specific DNA binding [Evidence IEA]; go_function: GO:0046982 - protein heterodimerization activity [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_20436A COG:K; EggNog:ENOG410PJYV; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_20437A COG:S; EggNog:ENOG410PKUF; InterPro:IPR001077,IPR036388,IPR016461,IPR029063, IPR036390; PFAM:PF00891; go_function: GO:0008168 - methyltransferase activity [Evidence IEA]; go_function: GO:0008171 - O-methyltransferase activity [Evidence IEA] AKAW2_20438S COG:S; EggNog:ENOG410Q1WG; TransMembrane:7 (o17-38i50-74o94-115i127-148o178-200i212-230o261-279i) AKAW2_20439A BUSCO:EOG09262X01; COG:L; EggNog:ENOG410PKSW; InterPro:IPR032466,IPR001130; PFAM:PF01026; go_function: GO:0016788 - hydrolase activity, acting on ester bonds [Evidence IEA] AKAW2_20440S COG:S; EggNog:ENOG410PRA7; TransMembrane:1 (n7-18c23/24o33-56i) AKAW2_20441A COG:I; EggNog:ENOG410PKS1; InterPro:IPR000073,IPR022742,IPR029058; MEROPS:MER0011785 AKAW2_20442S COG:S; EggNog:ENOG410PIZ8; InterPro:IPR005605; PFAM:PF03907; TransMembrane:2 (i92-110o134-152i); go_function: GO:0019888 - protein phosphatase regulator activity [Evidence IEA] AKAW2_20443A COG:L; EggNog:ENOG410PFNC; InterPro:IPR027417,IPR003593,IPR001208,IPR041562, IPR027925,IPR033762,IPR008046,IPR031327,IPR012340, IPR018525; PFAM:PF00493,PF17207,PF17855,PF14551; go_component: GO:0042555 - MCM complex [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006260 - DNA replication [Evidence IEA]; go_process: GO:0006270 - DNA replication initiation [Evidence IEA]; go_process: GO:0032508 - DNA duplex unwinding [Evidence IEA] AKAW2_20444A CAZy:CBM50; COG:S; EggNog:ENOG410PSHX; InterPro:IPR018392,IPR036779; PFAM:PF01476; SECRETED:SignalP(1-15) AKAW2_20445A COG:O; EggNog:ENOG410PU84; InterPro:IPR011118,IPR029058; PFAM:PF07519; SECRETED:SignalP(1-15) AKAW2_20446S COG:O; EggNog:ENOG410PHEM; InterPro:IPR014851,IPR003959,IPR003960,IPR027417, IPR003593,IPR001270; PFAM:PF00004; TransMembrane:1 (o26-47i); go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA] AKAW2_20447A COG:S; EggNog:ENOG410PXY7; SECRETED:SignalP(1-23) AKAW2_20448A COG:S; EggNog:ENOG410PPEQ; InterPro:IPR002885,IPR011990; PFAM:PF13041,PF13812,PF17177,PF01535; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_20449S COG:U; EggNog:ENOG410PFE9; InterPro:IPR034652,IPR026258,IPR038253; PFAM:PF16969; go_component: GO:0005786 - signal recognition particle, endoplasmic reticulum targeting [Evidence IEA]; go_function: GO:0003723 - RNA binding [Evidence IEA]; go_function: GO:0005047 - signal recognition particle binding [Evidence IEA]; go_function: GO:0008312 - 7S RNA binding [Evidence IEA]; go_function: GO:0030942 - endoplasmic reticulum signal peptide binding [Evidence IEA]; go_process: GO:0006614 - SRP-dependent cotranslational protein targeting to membrane [Evidence IEA] AKAW2_20450S COG:Q; EggNog:ENOG410PIER; InterPro:IPR001128,IPR002403,IPR017972,IPR036396; PFAM:PF00067; TransMembrane:1 (o27-51i); go_function: GO:0004497 - monooxygenase activity [Evidence IEA]; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_20452S COG:D; EggNog:ENOG410QEEU; InterPro:IPR001763,IPR036873 AKAW2_20453A BUSCO:EOG092610ZY; COG:J; EggNog:ENOG410PFVW; InterPro:IPR023115,IPR005225,IPR015760,IPR027417, IPR000795,IPR004161,IPR009000,IPR036925; PFAM:PF00009,PF11987,PF03144,PF01926; go_function: GO:0003924 - GTPase activity [Evidence IEA]; go_function: GO:0005525 - GTP binding [Evidence IEA] AKAW2_20454A COG:S; EggNog:ENOG410PK0C; InterPro:IPR015943,IPR031297,IPR018846; PFAM:PF10433; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0006281 - DNA repair [Evidence IEA] AKAW2_20455S BUSCO:EOG092642UD; COG:T; EggNog:ENOG410PI6X; InterPro:IPR035969,IPR000195; PFAM:PF00566; TransMembrane:1 (o379-396i) AKAW2_20456S COG:S; EggNog:ENOG410PKFD; InterPro:IPR039765,IPR006977; PFAM:PF04893; TransMembrane:5 (i117-137o157-176i188-206o212-233i245-268o); go_component: GO:0005794 - Golgi apparatus [Evidence IEA]; go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0017137 - Rab GTPase binding [Evidence IEA]; go_process: GO:0016192 - vesicle-mediated transport [Evidence IEA] AKAW2_20457A COG:K; EggNog:ENOG410PI9J; InterPro:IPR033599,IPR021752; PFAM:PF11781; go_component: GO:0070860 - RNA polymerase I core factor complex [Evidence IEA]; go_function: GO:0001164 - RNA polymerase I core promoter sequence-specific DNA binding [Evidence IEA]; go_process: GO:0001188 - RNA polymerase I preinitiation complex assembly [Evidence IEA]; go_process: GO:0006360 - transcription by RNA polymerase I [Evidence IEA] AKAW2_20458A COG:J; EggNog:ENOG410PMXH; InterPro:IPR020189,IPR019769,IPR008991,IPR001884, IPR012340,IPR014722; PFAM:PF01287; go_function: GO:0003723 - RNA binding [Evidence IEA]; go_function: GO:0003746 - translation elongation factor activity [Evidence IEA]; go_function: GO:0043022 - ribosome binding [Evidence IEA]; go_process: GO:0045901 - positive regulation of translational elongation [Evidence IEA]; go_process: GO:0045905 - positive regulation of translational termination [Evidence IEA] AKAW2_20459S BUSCO:EOG092621GA; COG:U,Z; EggNog:ENOG410PHT9; InterPro:IPR007258; PFAM:PF04129 AKAW2_20460S COG:E; EggNog:ENOG410PHK4; InterPro:IPR006076,IPR036188; PFAM:PF01266,PF13450; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_20461S COG:S; EggNog:ENOG410Q230 AKAW2_20462A COG:K; EggNog:ENOG410PUAT; InterPro:IPR036236,IPR007219,IPR013087; PFAM:PF04082,PF00096,PF12874; TransMembrane:3 (i376-401o421-440i718-738o); go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA] AKAW2_20463A COG:F; EggNog:ENOG410PJWB; InterPro:IPR000845,IPR035994; PFAM:PF01048; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_process: GO:0009116 - nucleoside metabolic process [Evidence IEA] AKAW2_20464A COG:E; EggNog:ENOG410PIY5; InterPro:IPR014710,IPR011051,IPR005708; PFAM:PF04209; go_function: GO:0004411 - homogentisate 1,2-dioxygenase activity [Evidence IEA]; go_process: GO:0006559 - L-phenylalanine catabolic process [Evidence IEA]; go_process: GO:0006570 - tyrosine metabolic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_20465S COG:S; EggNog:ENOG410PUHH; InterPro:IPR039461 AKAW2_20466S COG:S; EggNog:ENOG410PUHH; InterPro:IPR039461; MEROPS:MER0118932 AKAW2_20468S COG:C; EggNog:ENOG410PMDR; InterPro:IPR004165,IPR012792,IPR012791,IPR037171, IPR014388; PFAM:PF01144; go_function: GO:0008410 - CoA-transferase activity [Evidence IEA]; go_process: GO:0046952 - ketone body catabolic process [Evidence IEA] AKAW2_20470A COG:S; EggNog:ENOG410PZHJ; InterPro:IPR036864,IPR001138; PFAM:PF00172; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_20471S COG:E; EggNog:ENOG410Q2HG; InterPro:IPR024084,IPR011829; PFAM:PF00180; go_function: GO:0016616 - oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Evidence IEA]; go_function: GO:0051287 - NAD binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_20472S COG:K; EggNog:ENOG410PWBP; InterPro:IPR007219; PFAM:PF04082; TransMembrane:1 (o510-530i); go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA] AKAW2_20473A COG:A; EggNog:ENOG410PFWK; InterPro:IPR000504,IPR002004,IPR006515,IPR035979, IPR012677,IPR036053; PFAM:PF00658,PF13893,PF00076; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0003723 - RNA binding [Evidence IEA] AKAW2_20474A COG:O; EggNog:ENOG410PFFK; InterPro:IPR000569,IPR000048,IPR035983; PFAM:PF00632; go_function: GO:0004842 - ubiquitin-protein transferase activity [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_20475A COG:J; EggNog:ENOG410PSKU; InterPro:IPR019189; PFAM:PF09809 AKAW2_20476S BUSCO:EOG09261UPM; COG:A; EggNog:ENOG410PIBM; InterPro:IPR006709; PFAM:PF04615; go_component: GO:0032040 - small-subunit processome [Evidence IEA]; go_process: GO:0006364 - rRNA processing [Evidence IEA] AKAW2_20478S COG:G; EggNog:ENOG410PGKK; InterPro:IPR040720,IPR040451,IPR005200; PFAM:PF17652,PF03639; SECRETED:SignalP(1-24); go_function: GO:0052861 - glucan endo-1,3-beta-glucanase activity, C-3 substituted reducing group [Evidence IEA] AKAW2_20479S COG:P; EggNog:ENOG410PFNX; InterPro:IPR004798,IPR004837,IPR004713; PFAM:PF01699; TransMembrane:10 (o78-95i102-120o132-153i165-184o204-222i234-256o295- 316i361-388o394-415i422-442o); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0008324 - cation transmembrane transporter activity [Evidence IEA]; go_function: GO:0015369 - calcium:proton antiporter activity [Evidence IEA]; go_process: GO:0006812 - cation transport [Evidence IEA]; go_process: GO:0006816 - calcium ion transport [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_20480S BUSCO:EOG09264R1U; COG:J; EggNog:ENOG410PG3E; InterPro:IPR023798,IPR036823,IPR000235; PFAM:PF00177; go_process: GO:0006412 - translation [Evidence IEA] AKAW2_20481S COG:P; EggNog:ENOG410PIQM; InterPro:IPR001898,IPR004331; PFAM:PF03600,PF00939; TransMembrane:12 (o395-420i432-463o483-508i529-559o571-593i614-637o657- 674i681-703o709-729i750-776o796-821i842-864o); go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_20482A COG:S; EggNog:ENOG410PSUX AKAW2_20483S COG:S; EggNog:ENOG410PTF7 AKAW2_20484S COG:S; EggNog:ENOG410PR5S; InterPro:IPR037119,IPR019595; PFAM:PF10615; TransMembrane:2 (i104-121o182-202i) AKAW2_20485S COG:J; EggNog:ENOG410PI2H; InterPro:IPR001047,IPR022309; PFAM:PF01201; go_component: GO:0005840 - ribosome [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_process: GO:0006412 - translation [Evidence IEA] AKAW2_20486S COG:S; EggNog:ENOG410PNNZ; InterPro:IPR004843,IPR029052; PFAM:PF00149; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_20487A COG:T; EggNog:ENOG410PFQZ; InterPro:IPR042455,IPR027357,IPR032376,IPR043161, IPR035892,IPR036028,IPR027007,IPR010703,IPR026791, IPR001452; PFAM:PF00018,PF16172,PF14429,PF06920; go_function: GO:0005085 - guanyl-nucleotide exchange factor activity [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0007264 - small GTPase mediated signal transduction [Evidence IEA] AKAW2_20488A COG:U; EggNog:ENOG410PHSF; InterPro:IPR028258,IPR019160; PFAM:PF09763,PF15277; go_component: GO:0000145 - exocyst [Evidence IEA]; go_process: GO:0006887 - exocytosis [Evidence IEA] AKAW2_20489A TransMembrane:1 (n3-10c28/29o52-83i) AKAW2_20490A COG:Q; EggNog:ENOG410PPCV; InterPro:IPR036291,IPR002347; PFAM:PF00106,PF13561; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_20491S COG:S; EggNog:ENOG410PUY3; InterPro:IPR022698,IPR021858; PFAM:PF12013 AKAW2_20492S COG:S; EggNog:ENOG410PTY3; InterPro:IPR006594,IPR007718; PFAM:PF05022; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_20493A COG:S; EggNog:ENOG410PPX1; InterPro:IPR001810,IPR036322,IPR036047; PFAM:PF00646,PF12937; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_20494S COG:Q; EggNog:ENOG410PVE4; InterPro:IPR001128,IPR017972,IPR002401,IPR036396; PFAM:PF00067; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_20495A COG:J; EggNog:ENOG410PS65; InterPro:IPR017264; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_process: GO:0032543 - mitochondrial translation [Evidence IEA] AKAW2_20496S COG:S; EggNog:ENOG410PG9T; InterPro:IPR018961; PFAM:PF09350 AKAW2_20497S COG:S; EggNog:ENOG410PJQ4; SECRETED:SignalP(1-16); TransMembrane:1 (n4-15c20/21o44-68i) AKAW2_20498S COG:S; EggNog:ENOG410PUNJ; InterPro:IPR021840; PFAM:PF11915; TransMembrane:7 (i20-39o59-76i123-146o475-493i616-636o648-669i1116-1136o) AKAW2_20499A COG:J; EggNog:ENOG410PKR2; InterPro:IPR019432,IPR016181; PFAM:PF13523; go_function: GO:0016746 - transferase activity, transferring acyl groups [Evidence IEA]; go_process: GO:0019290 - siderophore biosynthetic process [Evidence IEA] AKAW2_20500A COG:E; EggNog:ENOG410PFQN; InterPro:IPR036291,IPR003462; PFAM:PF02423,PF01488 AKAW2_20501A COG:S; EggNog:ENOG410PN37; InterPro:IPR006671,IPR036915,IPR012104; PFAM:PF08613,PF00134; go_function: GO:0019901 - protein kinase binding [Evidence IEA]; go_process: GO:0000079 - regulation of cyclin-dependent protein serine/threonine kinase activity [Evidence IEA]; go_process: GO:0051726 - regulation of cell cycle [Evidence IEA] AKAW2_20502A CAZy:GH12; COG:G; EggNog:ENOG410PNCX; InterPro:IPR002594,IPR013319,IPR013320; PFAM:PF01670; SECRETED:SignalP(1-15); go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_function: GO:0008810 - cellulase activity [Evidence IEA]; go_process: GO:0000272 - polysaccharide catabolic process [Evidence IEA] AKAW2_20503S COG:I; EggNog:ENOG410PGCM; InterPro:IPR006716; PFAM:PF04622; SECRETED:SignalP(1-19) AKAW2_20504S BUSCO:EOG09262IZ6; COG:D; EggNog:ENOG410PFE0; InterPro:IPR011063,IPR032442,IPR014729,IPR000541; PFAM:PF01171,PF16503; go_function: GO:0000049 - tRNA binding [Evidence IEA]; go_process: GO:0002098 - tRNA wobble uridine modification [Evidence IEA]; go_process: GO:0034227 - tRNA thio-modification [Evidence IEA] AKAW2_20505A COG:S; EggNog:ENOG410PSJ2; InterPro:IPR039196; PFAM:PF13233; go_process: GO:0033615 - mitochondrial proton-transporting ATP synthase complex assembly [Evidence IEA] AKAW2_20506A COG:T; EggNog:ENOG410PG76; InterPro:IPR000651,IPR036964,IPR027417,IPR023578, IPR008937,IPR001895; PFAM:PF00617,PF00618; go_function: GO:0005085 - guanyl-nucleotide exchange factor activity [Evidence IEA]; go_process: GO:0007264 - small GTPase mediated signal transduction [Evidence IEA] AKAW2_20507A COG:S; EggNog:ENOG410PZIG; InterPro:IPR040197,IPR007529; PFAM:PF04438 AKAW2_20508S COG:S; EggNog:ENOG410PYQ3; InterPro:IPR036864,IPR021858,IPR001138; PFAM:PF00172,PF11951; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_20509S COG:O; EggNog:ENOG410PJ96; InterPro:IPR034904,IPR001075,IPR036498,IPR014824, IPR035433; PFAM:PF01106,PF08712; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0051536 - iron-sulfur cluster binding [Evidence IEA]; go_process: GO:0016226 - iron-sulfur cluster assembly [Evidence IEA] AKAW2_20510S COG:S; EggNog:ENOG410PGK6; InterPro:IPR007557; PFAM:PF04468 AKAW2_20511S BUSCO:EOG09264L0C; COG:J; EggNog:ENOG410PG8Y; InterPro:IPR000439,IPR012678,IPR020925,IPR024794; PFAM:PF00827; go_component: GO:0005840 - ribosome [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_process: GO:0006412 - translation [Evidence IEA] AKAW2_20512S COG:O; EggNog:ENOG410PH0X AKAW2_20513S COG:O; EggNog:ENOG410PH0X; InterPro:IPR000569,IPR035983; PFAM:PF00632; TransMembrane:1 (o618-639i); go_function: GO:0004842 - ubiquitin-protein transferase activity [Evidence IEA] AKAW2_20514S COG:Q; EggNog:ENOG410PIGG; InterPro:IPR013154,IPR013149,IPR002328,IPR036291, IPR011032,IPR020843; PFAM:PF00107,PF08240,PF16912,PF13602; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_20516S COG:Z; EggNog:ENOG410PJ27; InterPro:IPR010414,IPR008999; PFAM:PF06229 AKAW2_20515A COG:O; EggNog:ENOG410PM1V; InterPro:IPR001841,IPR013083; PFAM:PF17123,PF13923,PF00097,PF13639; TransMembrane:1 (n6-14c22/23o211-236i) AKAW2_20517S BUSCO:EOG09261EMF; COG:B; EggNog:ENOG410PFND; InterPro:IPR019340; PFAM:PF10198 AKAW2_20518A BUSCO:EOG09262H34; COG:P; EggNog:ENOG410PHY7; InterPro:IPR009348; PFAM:PF06218; TransMembrane:1 (i230-249o) AKAW2_20519A COG:S; EggNog:ENOG410PPK9 AKAW2_20520S COG:L; EggNog:ENOG410PJ6Q; InterPro:IPR036866,IPR011084,IPR001279; PFAM:PF12706 AKAW2_20521A COG:F; EggNog:ENOG410PFDJ; InterPro:IPR011612,IPR002019,IPR036461,IPR017951, IPR006680,IPR002026,IPR036463,IPR005848,IPR011059, IPR017950,IPR029754,IPR032466; MEROPS:MER0004801; PFAM:PF00449,PF01979,PF00699; go_component: GO:0035550 - urease complex [Evidence IEA]; go_function: GO:0009039 - urease activity [Evidence IEA]; go_function: GO:0016151 - nickel cation binding [Evidence IEA]; go_function: GO:0016787 - hydrolase activity [Evidence IEA]; go_function: GO:0016810 - hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [Evidence IEA]; go_process: GO:0006807 - nitrogen compound metabolic process [Evidence IEA]; go_process: GO:0043419 - urea catabolic process [Evidence IEA] AKAW2_20522A COG:B; EggNog:ENOG410PMG6; InterPro:IPR009071,IPR036910; PFAM:PF00505,PF09011 AKAW2_20523A COG:M; EggNog:ENOG410PFBX; InterPro:IPR001834,IPR008333,IPR001433,IPR017927, IPR001709,IPR017938,IPR039261; PFAM:PF00175,PF00970; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_20524A COG:J; EggNog:ENOG410PJYU; InterPro:IPR023573,IPR028877,IPR021138; PFAM:PF01775; go_component: GO:0005840 - ribosome [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_process: GO:0006412 - translation [Evidence IEA] AKAW2_20525S COG:D; EggNog:ENOG410PG8H; InterPro:IPR036388,IPR000717; PFAM:PF01399 AKAW2_20526A COG:S; EggNog:ENOG410PMED; InterPro:IPR000210,IPR011333; PFAM:PF00651; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_20528A BUSCO:EOG09263QPR; COG:O; EggNog:ENOG410PIAN; InterPro:IPR027370,IPR037683,IPR013144,IPR044063, IPR013083,IPR027711,IPR024964; PFAM:PF10607,PF13445; TransMembrane:1 (o302-319i); go_function: GO:0004842 - ubiquitin-protein transferase activity [Evidence IEA] AKAW2_20529S COG:S; EggNog:ENOG410PJ9C; InterPro:IPR038919 AKAW2_20530A COG:U; EggNog:ENOG410PS46; InterPro:IPR004217,IPR035427,IPR027100; PFAM:PF02953; go_component: GO:0042719 - mitochondrial intermembrane space protein transporter complex [Evidence IEA]; go_process: GO:0045039 - protein insertion into mitochondrial inner membrane [Evidence IEA] AKAW2_20531S COG:J; EggNog:ENOG410PFJ1; InterPro:IPR006195,IPR018149,IPR044136,IPR004365, IPR004364,IPR012340,IPR002313; PFAM:PF01336,PF00152; go_component: GO:0005737 - cytoplasm [Evidence IEA]; go_function: GO:0000166 - nucleotide binding [Evidence IEA]; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0004812 - aminoacyl-tRNA ligase activity [Evidence IEA]; go_function: GO:0004824 - lysine-tRNA ligase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006418 - tRNA aminoacylation for protein translation [Evidence IEA]; go_process: GO:0006430 - lysyl-tRNA aminoacylation [Evidence IEA] AKAW2_20532S COG:S; EggNog:ENOG410PH7F; InterPro:IPR027443 AKAW2_20533A COG:S; EggNog:ENOG410Q08Z; InterPro:IPR017956,IPR031915,IPR018839,IPR038986; PFAM:PF10383,PF16761; go_component: GO:0070824 - SHREC complex [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_process: GO:0006342 - chromatin silencing [Evidence IEA] AKAW2_20534A COG:I; EggNog:ENOG410PFQV; InterPro:IPR017871,IPR027417,IPR003593,IPR011527, IPR003439,IPR036640; PFAM:PF06472,PF00005; TransMembrane:1 (i38-59o); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA]; go_function: GO:0042626 - ATPase-coupled transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_20535S COG:K; EggNog:ENOG410PF8F; InterPro:IPR036412,IPR011948,IPR023214,IPR004274; PFAM:PF03031; go_function: GO:0016791 - phosphatase activity [Evidence IEA] AKAW2_20536S TransMembrane:1 (o69-89i) AKAW2_20537S BUSCO:EOG09263GUT; COG:T; EggNog:ENOG410PGGJ; InterPro:IPR001611,IPR003591,IPR032675,IPR025875; PFAM:PF13516,PF12799; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_20538A COG:S; EggNog:ENOG410PTC4 AKAW2_20539A COG:C; EggNog:ENOG410PFWU; InterPro:IPR018170,IPR020471,IPR036812,IPR023210; PFAM:PF00248; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_20540A COG:K; EggNog:ENOG410PSAR; InterPro:IPR038096,IPR000818; PFAM:PF01285; go_function: GO:0003700 - DNA-binding transcription factor activity [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_20541A COG:A; EggNog:ENOG410PFH8; InterPro:IPR000504,IPR035979,IPR012677,IPR034482; PFAM:PF13893,PF00076; go_function: GO:0003676 - nucleic acid binding [Evidence IEA] AKAW2_20542S COG:Z; EggNog:ENOG410PRDG; InterPro:IPR019763,IPR037177,IPR001372; PFAM:PF01221; go_component: GO:0005875 - microtubule associated complex [Evidence IEA]; go_component: GO:0030286 - dynein complex [Evidence IEA]; go_process: GO:0007017 - microtubule-based process [Evidence IEA] AKAW2_20543S COG:S; EggNog:ENOG410PS6Z AKAW2_20544A COG:P; EggNog:ENOG410PH3R; InterPro:IPR001734,IPR038377,IPR031155; PFAM:PF00474; TransMembrane:15 (o16-39i59-79o94-114i135-156o162-187i199-218o259-280i292- 318o344-373i394-419o425-446i453-473o493-515i570-590o602- 627i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0015204 - urea transmembrane transporter activity [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA]; go_process: GO:0071918 - urea transmembrane transport [Evidence IEA] AKAW2_20545S COG:E; EggNog:ENOG410PJRE; InterPro:IPR011146,IPR036265; go_function: GO:0003824 - catalytic activity [Evidence IEA] AKAW2_20546A COG:O; EggNog:ENOG410PRIY; InterPro:IPR016482,IPR030671; PFAM:PF03911; TransMembrane:1 (i99-117o); go_component: GO:0005784 - Sec61 translocon complex [Evidence IEA]; go_process: GO:0006886 - intracellular protein transport [Evidence IEA] AKAW2_20547S COG:S; EggNog:ENOG410PMEW; InterPro:IPR040410; TransMembrane:8 (i7-31o51-69i81-99o126-149i170-194o206-226i233-251o271- 292i) AKAW2_20548A COG:Q; EggNog:ENOG410Q2DA; InterPro:IPR034001,IPR043926,IPR027417,IPR003593, IPR010929,IPR017871,IPR029481,IPR003439,IPR013525, IPR034003; PFAM:PF01061,PF00005,PF06422,PF14510; TransMembrane:14 (i480-504o516-534i546-564o570-586i593-611o623-643i728- 745o1142-1160i1172-1191o1225-1243i1255-1278o1284- 1302i1314-1333o1407-1427i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA]; go_function: GO:0042626 - ATPase-coupled transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_20549A COG:L; EggNog:ENOG410PINW; InterPro:IPR022659,IPR022648,IPR022649,IPR000730; PFAM:PF04139,PF00705,PF02144,PF02747; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0030337 - DNA polymerase processivity factor activity [Evidence IEA]; go_process: GO:0006275 - regulation of DNA replication [Evidence IEA] AKAW2_20550S COG:S; EggNog:ENOG410PHFD; InterPro:IPR036291,IPR001509; PFAM:PF01118,PF01073,PF01370; go_function: GO:0003824 - catalytic activity [Evidence IEA] AKAW2_20551A COG:S; EggNog:ENOG410PK0E; InterPro:IPR026859; PFAM:PF12632; TransMembrane:1 (o177-195i); go_function: GO:0017022 - myosin binding [Evidence IEA] AKAW2_20552S COG:Z; EggNog:ENOG410PJ2A; InterPro:IPR001715,IPR000048,IPR036872; PFAM:PF00307; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_20554S COG:S; EggNog:ENOG410PKDP; InterPro:IPR018853; PFAM:PF10446 AKAW2_20555S COG:U; EggNog:ENOG410PFM2; InterPro:IPR005225,IPR027417,IPR006687,IPR006689; PFAM:PF00025,PF08477,PF00071,PF01926,PF09439; go_function: GO:0005525 - GTP binding [Evidence IEA]; go_process: GO:0006886 - intracellular protein transport [Evidence IEA] AKAW2_20556A COG:T; EggNog:ENOG410QDCN; InterPro:IPR029052,IPR031675,IPR006186,IPR004843; PFAM:PF00149,PF16891; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_20557A COG:S; EggNog:ENOG410PKC5; InterPro:IPR001611,IPR032675; PFAM:PF13855; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_20558S COG:I; EggNog:ENOG410PGZQ; InterPro:IPR021771,IPR016035,IPR002641; PFAM:PF11815,PF01734; TransMembrane:1 (i116-140o); go_function: GO:0004806 - triglyceride lipase activity [Evidence IEA]; go_process: GO:0006629 - lipid metabolic process [Evidence IEA] AKAW2_20559A BUSCO:EOG09260CMZ; COG:K; EggNog:ENOG410PINK; InterPro:IPR039340,IPR011990,IPR019734,IPR013026; PFAM:PF13432,PF14559; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0006383 - transcription by RNA polymerase III [Evidence IEA] AKAW2_20560S COG:J,T; EggNog:ENOG410QD6F; InterPro:IPR037635,IPR013761,IPR001660; PFAM:PF07647; go_function: GO:0003729 - mRNA binding [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0043488 - regulation of mRNA stability [Evidence IEA] AKAW2_20561S COG:S; EggNog:ENOG410PRGN; InterPro:IPR029008,IPR008504; PFAM:PF07019; TransMembrane:3 (i30-47o53-73i120-141o); go_component: GO:0005783 - endoplasmic reticulum [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_component: GO:0072546 - ER membrane protein complex [Evidence IEA] AKAW2_20562A COG:G; EggNog:ENOG410PH3Y; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF06609; TransMembrane:14 (i81-106o118-138i150-170o176-194i206-227o233-253i273- 300o312-332i361-388o400-419i426-447o453-471i491-511o560- 587i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_20563A COG:P; EggNog:ENOG410PFD9; InterPro:IPR002645,IPR001902,IPR018045,IPR036513, IPR011547; PFAM:PF00916,PF01740; TransMembrane:9 (o91-109i121-140o146-164i176-197o203-222i252-272o292- 314i421-444o478-510i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0008271 - secondary active sulfate transmembrane transporter activity [Evidence IEA]; go_function: GO:0015116 - sulfate transmembrane transporter activity [Evidence IEA]; go_process: GO:0008272 - sulfate transport [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_20564A BUSCO:EOG092632TF; COG:S; EggNog:ENOG410PM4G; InterPro:IPR036322,IPR028884; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0036265 - RNA (guanine-N7)-methylation [Evidence IEA] AKAW2_20565S BUSCO:EOG09264G1I; COG:J; EggNog:ENOG410PGUR; InterPro:IPR001790,IPR043141,IPR040637,IPR043164, IPR030670; PFAM:PF00428,PF17777,PF00466; go_process: GO:0042254 - ribosome biogenesis [Evidence IEA] AKAW2_20566S BUSCO:EOG09262JZK; COG:H; EggNog:ENOG410PGWW; InterPro:IPR000257,IPR006361,IPR038071; PFAM:PF01208; go_function: GO:0004853 - uroporphyrinogen decarboxylase activity [Evidence IEA]; go_process: GO:0006779 - porphyrin-containing compound biosynthetic process [Evidence IEA] AKAW2_20567A COG:F; EggNog:ENOG410PNUF; InterPro:IPR002125,IPR016193; PFAM:PF14437,PF00383; go_function: GO:0003824 - catalytic activity [Evidence IEA] AKAW2_20568S COG:O; EggNog:ENOG410PG3M; InterPro:IPR008971,IPR002939,IPR001623,IPR036869, IPR012724,IPR001305,IPR036410,IPR018253; PFAM:PF00684,PF01556; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0031072 - heat shock protein binding [Evidence IEA]; go_function: GO:0051082 - unfolded protein binding [Evidence IEA]; go_process: GO:0006457 - protein folding [Evidence IEA]; go_process: GO:0009408 - response to heat [Evidence IEA] AKAW2_20569A BUSCO:EOG092612AK; COG:U; EggNog:ENOG410PGSP; InterPro:IPR039766,IPR007234; PFAM:PF04100,PF10475; go_component: GO:0000938 - GARP complex [Evidence IEA]; go_process: GO:0042147 - retrograde transport, endosome to Golgi [Evidence IEA] AKAW2_20570A BUSCO:EOG09263MNN; COG:A; EggNog:ENOG410PK9N; InterPro:IPR002075,IPR005637,IPR009060,IPR018222, IPR032710,IPR032675,IPR030217; PFAM:PF03943,PF02136; go_component: GO:0005634 - nucleus [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0051028 - mRNA transport [Evidence IEA] AKAW2_20571S COG:U; EggNog:ENOG410PH7U; InterPro:IPR012936,IPR039542; PFAM:PF07970,PF13850; TransMembrane:2 (i20-43o400-421i) AKAW2_20572A COG:S; EggNog:ENOG410PG3N; InterPro:IPR001849,IPR011993 AKAW2_20573S COG:S; EggNog:ENOG410PZJT AKAW2_20574A COG:K; EggNog:ENOG410PIPG; InterPro:IPR036236,IPR013087; PFAM:PF00096 AKAW2_20575S BUSCO:EOG09265552; COG:K; EggNog:ENOG410PQRP; InterPro:IPR012293,IPR028363,IPR006111,IPR006110, IPR020708,IPR036161; PFAM:PF01192; go_component: GO:0005634 - nucleus [Evidence IEA]; go_component: GO:0005665 - RNA polymerase II, core complex [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0003899 - DNA-directed 5'-3' RNA polymerase activity [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA] AKAW2_20576S COG:G; EggNog:ENOG410Q17K; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i48-68o88-110i117-136o142-163i175-194o206-226i247- 267o273-292i313-333o339-364i376-397o403-424i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_20577A BUSCO:EOG09264ABT; COG:S; EggNog:ENOG410PNTA; InterPro:IPR000182,IPR016181; PFAM:PF13673,PF00583; go_function: GO:0008080 - N-acetyltransferase activity [Evidence IEA] AKAW2_20578S COG:S; EggNog:ENOG410PP3S AKAW2_20579A BUSCO:EOG0926112A; COG:J; EggNog:ENOG410PJ0Z; InterPro:IPR027512,IPR000717; PFAM:PF01399; go_component: GO:0005852 - eukaryotic translation initiation factor 3 complex [Evidence IEA] AKAW2_20580S COG:S; EggNog:ENOG410PR1T; InterPro:IPR036284,IPR015898,IPR041848; PFAM:PF00631; go_function: GO:0031681 - G-protein beta-subunit binding [Evidence IEA]; go_process: GO:0000750 - pheromone-dependent signal transduction involved in conjugation with cellular fusion [Evidence IEA]; go_process: GO:0007186 - G protein-coupled receptor signaling pathway [Evidence IEA] AKAW2_20581S COG:O; EggNog:ENOG410PQTE; InterPro:IPR011893,IPR036249; PFAM:PF10262 AKAW2_20582A COG:T; EggNog:ENOG410PI3P; InterPro:IPR002073,IPR036971,IPR023088,IPR003607, IPR023174; PFAM:PF00233; go_function: GO:0004114 - 3',5'-cyclic-nucleotide phosphodiesterase activity [Evidence IEA]; go_function: GO:0008081 - phosphoric diester hydrolase activity [Evidence IEA]; go_process: GO:0007165 - signal transduction [Evidence IEA] AKAW2_20583A COG:B,K; EggNog:ENOG410PHEU; InterPro:IPR009057,IPR001025,IPR019787,IPR019786, IPR000949,IPR002219,IPR029617,IPR011011,IPR043151, IPR034732,IPR001965,IPR013083; PFAM:PF13832,PF13771,PF00628,PF01426,PF13831; go_function: GO:0003682 - chromatin binding [Evidence IEA]; go_process: GO:0035556 - intracellular signal transduction [Evidence IEA] AKAW2_20584A TransMembrane:1 (o34-59i) AKAW2_20585S COG:L; EggNog:ENOG410PH1T; InterPro:IPR027417,IPR036390,IPR001650,IPR014001, IPR011545; PFAM:PF04851,PF00270,PF00271; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA] AKAW2_20586A COG:S; EggNog:ENOG410PHCE; InterPro:IPR017946; SECRETED:SignalP(1-24); go_function: GO:0008081 - phosphoric diester hydrolase activity [Evidence IEA]; go_process: GO:0006629 - lipid metabolic process [Evidence IEA] AKAW2_20587S BUSCO:EOG09260EOI; COG:U; EggNog:ENOG410Q572; InterPro:IPR025941,IPR036322; PFAM:PF12816; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_20588S CAZy:GH16; COG:G; EggNog:ENOG410PK1Z; InterPro:IPR000757,IPR013320; SECRETED:SignalP(1-20); go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_20589S BUSCO:EOG09260ETR; COG:S; EggNog:ENOG410PGJP; InterPro:IPR007807,IPR027992,IPR032672,IPR000182, IPR033688,IPR013562; PFAM:PF13725,PF08351,PF05127,PF13718; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0008080 - N-acetyltransferase activity [Evidence IEA]; go_process: GO:0016072 - rRNA metabolic process [Evidence IEA]; go_process: GO:0034470 - ncRNA processing [Evidence IEA] AKAW2_20590A COG:O; EggNog:ENOG410PG1G; InterPro:IPR036249,IPR013766,IPR017937; PFAM:PF00085; SECRETED:SignalP(1-22) AKAW2_20591S COG:S; EggNog:ENOG410PMBA; InterPro:IPR001810,IPR036047; PFAM:PF00646,PF12937; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_20592A COG:O; EggNog:ENOG410PQ5F; InterPro:IPR001623,IPR036869; PFAM:PF00226 AKAW2_20593A COG:C; EggNog:ENOG410PH2F; InterPro:IPR023632,IPR000131,IPR035968; PFAM:PF00231; go_component: GO:0045261 - proton-transporting ATP synthase complex, catalytic core F(1) [Evidence IEA]; go_function: GO:0046933 - proton-transporting ATP synthase activity, rotational mechanism [Evidence IEA]; go_process: GO:0015986 - ATP synthesis coupled proton transport [Evidence IEA] AKAW2_20594S BUSCO:EOG09260MRU; COG:L; EggNog:ENOG410PHNU; InterPro:IPR013030,IPR018521,IPR001631,IPR013500, IPR025834,IPR036202,IPR011010,IPR008336,IPR013499, IPR014711,IPR014727,IPR013034; PFAM:PF01028,PF02919,PF14370; go_component: GO:0005694 - chromosome [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0003917 - DNA topoisomerase type I (single strand cut, ATP-independent) activity [Evidence IEA]; go_process: GO:0006265 - DNA topological change [Evidence IEA] AKAW2_20595A COG:E,I; EggNog:ENOG410PIIP; InterPro:IPR036291,IPR001509; PFAM:PF04321,PF01073,PF01370; go_function: GO:0003824 - catalytic activity [Evidence IEA] AKAW2_20596A COG:S; EggNog:ENOG410Q2SM AKAW2_20597A COG:U; EggNog:ENOG410PKA7; InterPro:IPR041212,IPR023175,IPR039431; PFAM:PF18097,PF04652 AKAW2_20598A COG:O,T; EggNog:ENOG410PMBU; InterPro:IPR022682,IPR022683,IPR007330,IPR036213, IPR036181,IPR038765,IPR001300; MEROPS:MER0005406; PFAM:PF00648,PF01067; go_function: GO:0004198 - calcium-dependent cysteine-type endopeptidase activity [Evidence IEA]; go_process: GO:0006508 - proteolysis [Evidence IEA] AKAW2_20599S COG:C; EggNog:ENOG410PKE3; InterPro:IPR018108,IPR023395,IPR002067; PFAM:PF00153; TransMembrane:5 (o12-32i77-99o119-142i214-234o283-307i); go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_20600S BUSCO:EOG092644K0; COG:L; EggNog:ENOG410PI41; InterPro:IPR016071,IPR035437; PFAM:PF00565; TransMembrane:1 (o39-58i) AKAW2_20601A COG:F; EggNog:ENOG410PM98; InterPro:IPR000850,IPR006259,IPR027417,IPR028586, IPR033690,IPR007862; PFAM:PF05191,PF00406,PF13207; go_component: GO:0005739 - mitochondrion [Evidence IEA]; go_function: GO:0004017 - adenylate kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016776 - phosphotransferase activity, phosphate group as acceptor [Evidence IEA]; go_function: GO:0019205 - nucleobase-containing compound kinase activity [Evidence IEA]; go_process: GO:0006139 - nucleobase-containing compound metabolic process [Evidence IEA] AKAW2_20602S BUSCO:EOG092626HU; COG:L; EggNog:ENOG410PIE0; InterPro:IPR007238,IPR016558; PFAM:PF04104; go_process: GO:0006269 - DNA replication, synthesis of RNA primer [Evidence IEA] AKAW2_20603S COG:U; EggNog:ENOG410PGI6; InterPro:IPR007123,IPR036180,IPR012990,IPR036465, IPR006895,IPR006896,IPR037550,IPR036174,IPR036175, IPR037364,IPR006900,IPR029006; PFAM:PF04810,PF08033,PF04815,PF00626,PF04811; go_component: GO:0030127 - COPII vesicle coat [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006886 - intracellular protein transport [Evidence IEA]; go_process: GO:0006888 - endoplasmic reticulum to Golgi vesicle-mediated transport [Evidence IEA]; go_process: GO:0090114 - COPII-coated vesicle budding [Evidence IEA] AKAW2_20604S BUSCO:EOG092651LN; COG:J; EggNog:ENOG410PN4A; InterPro:IPR020784,IPR036769,IPR000911,IPR020783, IPR036796; PFAM:PF03946,PF00298; go_component: GO:0005840 - ribosome [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_process: GO:0006412 - translation [Evidence IEA] AKAW2_20605S COG:G,O,T; EggNog:ENOG410QDZS; InterPro:IPR011990,IPR029489,IPR019734,IPR013026; PFAM:PF13181; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_20606A COG:S; EggNog:ENOG410PSBH AKAW2_20607A COG:K; EggNog:ENOG410PPPF; InterPro:IPR001005,IPR009057,IPR017930; PFAM:PF00249,PF13921 AKAW2_20609A CAZy:GH31; COG:G,M,O; EggNog:ENOG410PKMC; InterPro:IPR017853,IPR011013,IPR000322,IPR013780; PFAM:PF01055; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_function: GO:0030246 - carbohydrate binding [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_20610S COG:S; EggNog:ENOG410PTZ7; InterPro:IPR019416; PFAM:PF10309; go_function: GO:0000340 - RNA 7-methylguanosine cap binding [Evidence IEA]; go_function: GO:0003729 - mRNA binding [Evidence IEA] AKAW2_20611S COG:S; EggNog:ENOG410PP42; InterPro:IPR036322,IPR006594; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_20612A COG:J; EggNog:ENOG410PRZJ; InterPro:IPR002673; PFAM:PF01779; go_component: GO:0005840 - ribosome [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_process: GO:0006412 - translation [Evidence IEA] AKAW2_20613S BUSCO:EOG092657H8; COG:C; EggNog:ENOG410PN8K; InterPro:IPR001469,IPR020546,IPR036771; PFAM:PF02823; go_component: GO:0045261 - proton-transporting ATP synthase complex, catalytic core F(1) [Evidence IEA]; go_function: GO:0046933 - proton-transporting ATP synthase activity, rotational mechanism [Evidence IEA]; go_process: GO:0015986 - ATP synthesis coupled proton transport [Evidence IEA] AKAW2_20614S TransMembrane:1 (o429-449i) AKAW2_20615A COG:S; EggNog:ENOG410PJQM; InterPro:IPR006593,IPR007128; PFAM:PF03188; TransMembrane:5 (o66-92i104-125o137-156i177-198o204-225i); go_component: GO:0000818 - nuclear MIS12/MIND complex [Evidence IEA] AKAW2_20616S COG:E; EggNog:ENOG410PIMV; InterPro:IPR005282,IPR006603; PFAM:PF04193; TransMembrane:7 (o12-30i51-73o93-117i129-149o161-183i195-218o238-258i) AKAW2_20617S COG:S; EggNog:ENOG410PRG3; InterPro:IPR036236,IPR013087 AKAW2_20618A COG:S; EggNog:ENOG410PNQI; InterPro:IPR036236,IPR013087; PFAM:PF00096 AKAW2_20620A COG:I; EggNog:ENOG410PHRI; InterPro:IPR011009,IPR002575,IPR041726; PFAM:PF01636 AKAW2_20621S COG:F; EggNog:ENOG410PNZB; InterPro:IPR036157,IPR008181,IPR029054,IPR033704; PFAM:PF00692; go_function: GO:0000287 - magnesium ion binding [Evidence IEA]; go_function: GO:0004170 - dUTP diphosphatase activity [Evidence IEA]; go_process: GO:0006226 - dUMP biosynthetic process [Evidence IEA]; go_process: GO:0046081 - dUTP catabolic process [Evidence IEA] AKAW2_20622A COG:H; EggNog:ENOG410PHE3; InterPro:IPR029056,IPR004625,IPR013749; PFAM:PF08543; go_function: GO:0008478 - pyridoxal kinase activity [Evidence IEA]; go_process: GO:0009443 - pyridoxal 5'-phosphate salvage [Evidence IEA] AKAW2_20623S COG:S; EggNog:ENOG410PP3Y; SECRETED:SignalP(1-37); TransMembrane:1 (n24-32c37/38o337-358i) AKAW2_20624A BUSCO:EOG09263690; COG:S; EggNog:ENOG410PFID; InterPro:IPR037516,IPR012860; PFAM:PF07792,PF08616 AKAW2_20625S COG:Z; EggNog:ENOG410PJ15; InterPro:IPR018247,IPR002048,IPR011992; PFAM:PF13405; go_function: GO:0005509 - calcium ion binding [Evidence IEA] AKAW2_20626S COG:U; EggNog:ENOG410PFKT; InterPro:IPR035969,IPR000195; PFAM:PF00566; TransMembrane:2 (o387-408i420-445o) AKAW2_20627A COG:A; EggNog:ENOG410PWN8; InterPro:IPR000504,IPR012677,IPR035979; PFAM:PF00076; go_function: GO:0003676 - nucleic acid binding [Evidence IEA] AKAW2_20629S COG:G; EggNog:ENOG410PISM; InterPro:IPR039104,IPR005900,IPR037171,IPR006148; PFAM:PF01182; go_function: GO:0017057 - 6-phosphogluconolactonase activity [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA]; go_process: GO:0006098 - pentose-phosphate shunt [Evidence IEA] AKAW2_20630S COG:S; EggNog:ENOG410PNQ4 AKAW2_20631S COG:S; EggNog:ENOG410PK2D; InterPro:IPR015943,IPR001680,IPR036322,IPR017986; PFAM:PF00400; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_20632S COG:S; EggNog:ENOG410PM06; InterPro:IPR001214,IPR002893; PFAM:PF00856; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_20633A BUSCO:EOG09263WM5; COG:S; EggNog:ENOG410PHRN; InterPro:IPR016024,IPR016021,IPR003890,IPR003891; PFAM:PF02847; go_function: GO:0003723 - RNA binding [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_20634S COG:O; EggNog:ENOG410PREN; InterPro:IPR009914; PFAM:PF07297; TransMembrane:2 (i9-30o50-71i); go_component: GO:0030176 - integral component of endoplasmic reticulum membrane [Evidence IEA]; go_function: GO:0030234 - enzyme regulator activity [Evidence IEA]; go_process: GO:0019348 - dolichol metabolic process [Evidence IEA] AKAW2_20635S COG:S; EggNog:ENOG410PMF8; InterPro:IPR015943,IPR036322; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_20636A COG:S; EggNog:ENOG410PYXG; SECRETED:SignalP(1-18) AKAW2_20637S BUSCO:EOG092614O9; COG:L; EggNog:ENOG410PH1A; InterPro:IPR027417,IPR001650,IPR014001,IPR006935, IPR039686,IPR003903; PFAM:PF00270,PF00271,PF04851; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016787 - hydrolase activity [Evidence IEA]; go_function: GO:0043138 - 3'-5' DNA helicase activity [Evidence IEA]; go_process: GO:0006281 - DNA repair [Evidence IEA] AKAW2_20638S COG:S; EggNog:ENOG410PYU2 AKAW2_20639S COG:Z; EggNog:ENOG410PH9Y; InterPro:IPR043175,IPR037282,IPR042276,IPR001698, IPR019771; PFAM:PF01115; go_component: GO:0005737 - cytoplasm [Evidence IEA]; go_component: GO:0008290 - F-actin capping protein complex [Evidence IEA]; go_function: GO:0003779 - actin binding [Evidence IEA]; go_process: GO:0030036 - actin cytoskeleton organization [Evidence IEA]; go_process: GO:0051016 - barbed-end actin filament capping [Evidence IEA] AKAW2_20640A COG:S; EggNog:ENOG410PSDC; InterPro:IPR019404; PFAM:PF10280; go_component: GO:0016592 - mediator complex [Evidence IEA]; go_function: GO:0003712 - transcription coregulator activity [Evidence IEA]; go_process: GO:0006357 - regulation of transcription by RNA polymerase II [Evidence IEA] AKAW2_20641S COG:K; EggNog:ENOG410PFWW; InterPro:IPR037783,IPR036322,IPR019775,IPR015943, IPR007582,IPR001680,IPR020472,IPR037264,IPR006594, IPR017986; PFAM:PF00400,PF08513,PF04494; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_20642A BUSCO:EOG09264E5J; COG:S; EggNog:ENOG410PI68; InterPro:IPR016812,IPR000073,IPR029058; MEROPS:MER0036069; PFAM:PF12697,PF00561; go_function: GO:0051723 - protein methylesterase activity [Evidence IEA]; go_process: GO:0006482 - protein demethylation [Evidence IEA] AKAW2_20643S BUSCO:EOG09261YRA; COG:S; EggNog:ENOG410PHE1; InterPro:IPR029058,IPR019431; PFAM:PF10329; TransMembrane:5 (i69-87o99-121i128-150o156-174i203-229o) AKAW2_20644A BUSCO:EOG09260UA2; COG:U; EggNog:ENOG410PFEI; InterPro:IPR029071,IPR037518,IPR016563,IPR007717, IPR007716; PFAM:PF05021,PF05020; go_process: GO:0006511 - ubiquitin-dependent protein catabolic process [Evidence IEA] AKAW2_20645A CAZy:AA6; COG:S; EggNog:ENOG410PGP7; InterPro:IPR005025,IPR029039,IPR010089,IPR008254; PFAM:PF02525,PF03358; go_function: GO:0003955 - NAD(P)H dehydrogenase (quinone) activity [Evidence IEA]; go_function: GO:0010181 - FMN binding [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA] AKAW2_20646A BUSCO:EOG092654KW; COG:A; EggNog:ENOG410PKZQ; InterPro:IPR000571,IPR036855; PFAM:PF00642; go_function: GO:0046872 - metal ion binding [Evidence IEA] AKAW2_20647S CAZy:GH18; COG:G; EggNog:ENOG410PFYY; InterPro:IPR011583,IPR029070,IPR001223,IPR017853, IPR001579; PFAM:PF00704; go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_function: GO:0008061 - chitin binding [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_20648A COG:S; EggNog:ENOG410PNSR; InterPro:IPR022185; PFAM:PF12505; TransMembrane:1 (i36-59o) AKAW2_20649A COG:S; EggNog:ENOG410PJP6; InterPro:IPR011990,IPR006597; PFAM:PF08238; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_20650S COG:S; EggNog:ENOG410PHWH; InterPro:IPR039860; TransMembrane:6 (i38-58o78-99i119-138o144-167i179-200o223-247i) AKAW2_20651A COG:S; EggNog:ENOG410PFR7; InterPro:IPR013952,IPR036291; PFAM:PF08643; TransMembrane:1 (o84-102i) AKAW2_20652S COG:D; EggNog:ENOG410PGBA; InterPro:IPR017441,IPR008271,IPR000719,IPR011009; PFAM:PF06293,PF07714,PF01163,PF00069; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_20653S COG:D; EggNog:ENOG410PGBA; InterPro:IPR000719,IPR011009; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_20655S COG:P; EggNog:ENOG410PHT8; InterPro:IPR013536,IPR001876; MEROPS:MER0215799; PFAM:PF08325 AKAW2_20656A COG:Q; EggNog:ENOG410PP6F; InterPro:IPR027443,IPR005123; PFAM:PF03171; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_20657A BUSCO:EOG09260EE7; COG:A; EggNog:ENOG410PG22; InterPro:IPR036322,IPR015943,IPR001680,IPR007148, IPR019775,IPR020472,IPR017986; PFAM:PF04003,PF00400; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_20658S BUSCO:EOG09263EQZ; COG:Z; EggNog:ENOG410PFCE; InterPro:IPR007188,IPR034666; PFAM:PF04045; go_component: GO:0005885 - Arp2/3 protein complex [Evidence IEA]; go_component: GO:0015629 - actin cytoskeleton [Evidence IEA]; go_process: GO:0030041 - actin filament polymerization [Evidence IEA]; go_process: GO:0030833 - regulation of actin filament polymerization [Evidence IEA]; go_process: GO:0034314 - Arp2/3 complex-mediated actin nucleation [Evidence IEA] AKAW2_20659S COG:S; EggNog:ENOG410Q1TR; InterPro:IPR001810,IPR036047,IPR032675; PFAM:PF00646; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_20660S COG:S; EggNog:ENOG410PX3Q AKAW2_20661S COG:T; EggNog:ENOG410PHX6; InterPro:IPR036457,IPR039123,IPR001932; go_function: GO:0016791 - phosphatase activity [Evidence IEA] AKAW2_20662S COG:S; EggNog:ENOG410PK1E; InterPro:IPR006984; PFAM:PF04900; go_component: GO:0032040 - small-subunit processome [Evidence IEA] AKAW2_20663A COG:S; EggNog:ENOG410PS0F; InterPro:IPR013892; PFAM:PF08583 AKAW2_20664S BUSCO:EOG09261DW8; COG:S; EggNog:ENOG410PGZV; InterPro:IPR036322,IPR015943,IPR001680,IPR019775, IPR020472,IPR017986; PFAM:PF00400; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_20665S COG:S; EggNog:ENOG410PR5J AKAW2_20666S BUSCO:EOG09261660; COG:K; EggNog:ENOG410PG3I; InterPro:IPR007991; PFAM:PF05327 AKAW2_20667A CAZy:CE10; COG:V; EggNog:ENOG410PN60; InterPro:IPR029058,IPR013094; MEROPS:MER0042911; PFAM:PF07859; SECRETED:SignalP(1-17); TransMembrane:1 (i12-30o); go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_20668S COG:J; EggNog:ENOG410PFAW; InterPro:IPR006195,IPR024320,IPR012340,IPR004364, IPR004523,IPR002312; PFAM:PF00152,PF09924; go_component: GO:0005737 - cytoplasm [Evidence IEA]; go_function: GO:0000166 - nucleotide binding [Evidence IEA]; go_function: GO:0004812 - aminoacyl-tRNA ligase activity [Evidence IEA]; go_function: GO:0004815 - aspartate-tRNA ligase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006418 - tRNA aminoacylation for protein translation [Evidence IEA]; go_process: GO:0006422 - aspartyl-tRNA aminoacylation [Evidence IEA] AKAW2_20669A COG:S; EggNog:ENOG410PQZA; InterPro:IPR019433; SECRETED:SignalP(1-32); TransMembrane:1 (n19-27c32/33o221-243i) AKAW2_20670S COG:Z; EggNog:ENOG410PFTH; InterPro:IPR023123,IPR008280,IPR036525,IPR037103, IPR000217,IPR018316,IPR003008,IPR002452,IPR017975; PFAM:PF03953,PF00091; go_component: GO:0005874 - microtubule [Evidence IEA]; go_function: GO:0003924 - GTPase activity [Evidence IEA]; go_function: GO:0005200 - structural constituent of cytoskeleton [Evidence IEA]; go_function: GO:0005525 - GTP binding [Evidence IEA]; go_process: GO:0007017 - microtubule-based process [Evidence IEA] AKAW2_20671S COG:T,U; EggNog:ENOG410PGRZ; InterPro:IPR011992,IPR009060,IPR002048,IPR015940, IPR018247,IPR000261; PFAM:PF12763,PF00627; go_function: GO:0005509 - calcium ion binding [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_20672A COG:P; EggNog:ENOG410PFW2; InterPro:IPR018303,IPR023298,IPR023299,IPR001757, IPR004014,IPR036412,IPR006534,IPR008250,IPR023214; PFAM:PF00122,PF00690,PF00702; TransMembrane:10 (i108-134o140-159i290-309o321-349i683-706o712-733i754- 776o791-811i823-844o856-874i); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0000166 - nucleotide binding [Evidence IEA]; go_function: GO:0008553 - proton-exporting ATPase activity, phosphorylative mechanism [Evidence IEA]; go_process: GO:0120029 - proton export across plasma membrane [Evidence IEA] AKAW2_20673S COG:S; EggNog:ENOG410PSGD; InterPro:IPR015943,IPR036322; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_20674A COG:L; EggNog:ENOG410PM6J; InterPro:IPR020796,IPR027417,IPR041664; PFAM:PF13191,PF14630; go_component: GO:0000808 - origin recognition complex [Evidence IEA]; go_component: GO:0005634 - nucleus [Evidence IEA]; go_process: GO:0006260 - DNA replication [Evidence IEA] AKAW2_20675A COG:J; EggNog:ENOG410PGBQ; InterPro:IPR001313,IPR016024,IPR011989,IPR033712, IPR033133; PFAM:PF00806; go_function: GO:0003723 - RNA binding [Evidence IEA] AKAW2_20676S COG:G; EggNog:ENOG410PJJ1; InterPro:IPR005829,IPR005828,IPR020846,IPR036259; TransMembrane:2 (o26-48i60-83o); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_20677S COG:K; EggNog:ENOG410PG3S; InterPro:IPR007120,IPR007121,IPR037034,IPR037033, IPR015712,IPR014724,IPR007642,IPR007641,IPR007647, IPR007646,IPR007645,IPR007644; PFAM:PF04561,PF00562,PF04567,PF04566,PF04563, PF04565,PF04560; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0003899 - DNA-directed 5'-3' RNA polymerase activity [Evidence IEA]; go_function: GO:0032549 - ribonucleoside binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA] AKAW2_20678A COG:S; EggNog:ENOG410PPK0; InterPro:IPR008547; PFAM:PF05705; TransMembrane:1 (o196-217i) AKAW2_20679A BUSCO:EOG09263WLB; COG:O; EggNog:ENOG410PG17; InterPro:IPR004854,IPR042299; PFAM:PF03152; go_process: GO:0006511 - ubiquitin-dependent protein catabolic process [Evidence IEA] AKAW2_20681S COG:S; EggNog:ENOG410PIE9; InterPro:IPR039905,IPR035445,IPR003169; PFAM:PF02213; go_component: GO:0005682 - U5 snRNP [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_20680A COG:L; EggNog:ENOG410PHPG; InterPro:IPR027238,IPR042487,IPR037942,IPR027417, IPR003593,IPR041048,IPR010339; PFAM:PF17856,PF06068; go_component: GO:0031011 - Ino80 complex [Evidence IEA]; go_component: GO:0035267 - NuA4 histone acetyltransferase complex [Evidence IEA]; go_component: GO:0097255 - R2TP complex [Evidence IEA]; go_function: GO:0003678 - DNA helicase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0043139 - 5'-3' DNA helicase activity [Evidence IEA] AKAW2_20682S COG:S; EggNog:ENOG410Q2RB AKAW2_20683A COG:S; EggNog:ENOG410PFB9; InterPro:IPR000073,IPR029058; MEROPS:MER0031610; PFAM:PF12697,PF00561 AKAW2_20684A COG:S; EggNog:ENOG410PQBS AKAW2_20685S COG:Q; EggNog:ENOG410PMFC; InterPro:IPR011234,IPR036663; PFAM:PF01557; go_function: GO:0003824 - catalytic activity [Evidence IEA] AKAW2_20686A COG:G; EggNog:ENOG410PHMC; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i80-103o115-133i145-168o174-192i204-227o233-252i297- 319o339-361i382-401o416-436i448-467o479-500i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_20688S COG:S; EggNog:ENOG410PRMF; InterPro:IPR036236,IPR013087,IPR007219; PFAM:PF00096,PF04082; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA] AKAW2_20689A COG:S; EggNog:ENOG410Q2YT AKAW2_20690S COG:S; EggNog:ENOG410PP61; InterPro:IPR029069,IPR042171; PFAM:PF13622; SECRETED:SignalP(1-19); TransMembrane:1 (n6-17c21/22o45-62i) AKAW2_20691A COG:S; EggNog:ENOG410PZW2 AKAW2_20692S COG:S; EggNog:ENOG410PYS8 AKAW2_20693A COG:S; EggNog:ENOG410PZZV AKAW2_20694A COG:Q; EggNog:ENOG410PKRN; InterPro:IPR001128,IPR017972,IPR002401,IPR036396; PFAM:PF00067; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_20696A COG:S; EggNog:ENOG410PMCI; InterPro:IPR029063; PFAM:PF13489,PF08241,PF13649 AKAW2_20697S COG:S; EggNog:ENOG410PMB2; InterPro:IPR011009,IPR002575; PFAM:PF01636 AKAW2_20698S COG:S; EggNog:ENOG410PRXH; InterPro:IPR011058,IPR036673; PFAM:PF08881 AKAW2_20699A COG:S; EggNog:ENOG410PGAN AKAW2_20700S COG:S; EggNog:ENOG410PHT4; InterPro:IPR018562; PFAM:PF09441 AKAW2_20701A COG:S; EggNog:ENOG410PU02 AKAW2_20703A COG:S; EggNog:ENOG410PR7E AKAW2_20704S COG:G; EggNog:ENOG410PKFM; InterPro:IPR029056,IPR002173,IPR011611,IPR034093; PFAM:PF00294; go_function: GO:0004454 - ketohexokinase activity [Evidence IEA]; go_function: GO:0016773 - phosphotransferase activity, alcohol group as acceptor [Evidence IEA]; go_process: GO:0006000 - fructose metabolic process [Evidence IEA] AKAW2_20705S COG:J; EggNog:ENOG410PGS3; InterPro:IPR007109,IPR026532; PFAM:PF04427 AKAW2_20706S COG:S; EggNog:ENOG410PFGH; InterPro:IPR036047; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_20707A BUSCO:EOG09264HHW; COG:U; EggNog:ENOG410PJC3; InterPro:IPR005225,IPR001806,IPR027417; PFAM:PF00025,PF08477,PF00071,PF01926; go_function: GO:0003924 - GTPase activity [Evidence IEA]; go_function: GO:0005525 - GTP binding [Evidence IEA] AKAW2_20708S COG:B; EggNog:ENOG410PUP3; InterPro:IPR016197,IPR023780,IPR000953; PFAM:PF00385 AKAW2_20709A COG:O; EggNog:ENOG410PFXS; InterPro:IPR003959,IPR027417,IPR003593,IPR019489; PFAM:PF10431,PF00004,PF07724,PF07728; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA] AKAW2_20710A COG:S; EggNog:ENOG410PRBD; InterPro:IPR028160; PFAM:PF15341; go_component: GO:0005730 - nucleolus [Evidence IEA]; go_component: GO:0030686 - 90S preribosome [Evidence IEA]; go_component: GO:0030688 - preribosome, small subunit precursor [Evidence IEA]; go_process: GO:0000462 - maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [Evidence IEA] AKAW2_20711S COG:C; EggNog:ENOG410PHMP; InterPro:IPR006109,IPR006168,IPR036291,IPR011128, IPR008927,IPR013328; PFAM:PF01210,PF07479; go_component: GO:0009331 - glycerol-3-phosphate dehydrogenase complex [Evidence IEA]; go_function: GO:0004367 - glycerol-3-phosphate dehydrogenase [NAD+] activity [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0016616 - oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Evidence IEA]; go_function: GO:0051287 - NAD binding [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA]; go_process: GO:0006072 - glycerol-3-phosphate metabolic process [Evidence IEA]; go_process: GO:0046168 - glycerol-3-phosphate catabolic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_20712S CAZy:GH133; COG:G; EggNog:ENOG410PHNJ; InterPro:IPR006421,IPR029436,IPR010401,IPR017853, IPR008928,IPR032790,IPR032792,IPR032788; PFAM:PF06202,PF14702,PF14701,PF14699; go_function: GO:0004134 - 4-alpha-glucanotransferase activity [Evidence IEA]; go_function: GO:0004135 - amylo-alpha-1,6-glucosidase activity [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA]; go_process: GO:0005978 - glycogen biosynthetic process [Evidence IEA]; go_process: GO:0005980 - glycogen catabolic process [Evidence IEA] AKAW2_20713S COG:S; EggNog:ENOG410PH8S; InterPro:IPR003864,IPR027815,IPR032880; PFAM:PF02714,PF14703,PF13967; TransMembrane:10 (o38-59i119-140o175-194i432-456o486-505i526-550o577- 595i635-663o686-711i718-736o); go_component: GO:0016020 - membrane [Evidence IEA] AKAW2_20714A COG:E; EggNog:ENOG410PG9I; InterPro:IPR013785,IPR006219,IPR006218; PFAM:PF00793; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0003849 - 3-deoxy-7-phosphoheptulonate synthase activity [Evidence IEA]; go_process: GO:0009058 - biosynthetic process [Evidence IEA]; go_process: GO:0009073 - aromatic amino acid family biosynthetic process [Evidence IEA] AKAW2_20715A COG:S; EggNog:ENOG410Q2H1 AKAW2_20716S COG:S; EggNog:ENOG410PNER; InterPro:IPR017939; TransMembrane:1 (o330-349i); go_function: GO:0003839 - gamma-glutamylcyclotransferase activity [Evidence IEA] AKAW2_20717A COG:C; EggNog:ENOG410PFPG; InterPro:IPR002326,IPR009056,IPR021157,IPR036909; PFAM:PF02167; TransMembrane:1 (o276-294i); go_function: GO:0009055 - electron transfer activity [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA] AKAW2_20718A COG:O; EggNog:ENOG410PJBC; InterPro:IPR003959,IPR003960,IPR027417,IPR003593, IPR001270; PFAM:PF00004; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA] AKAW2_20719S BUSCO:EOG09260NXJ; COG:U; EggNog:ENOG410PGCX; InterPro:IPR001810,IPR036047,IPR009976; PFAM:PF07393,PF00646,PF12937; go_component: GO:0005737 - cytoplasm [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0006887 - exocytosis [Evidence IEA] AKAW2_20720S COG:S; EggNog:ENOG410PMWK; InterPro:IPR014044,IPR001283,IPR034120,IPR018244, IPR035940; PFAM:PF00188; SECRETED:SignalP(1-33); TransMembrane:1 (n10-28c33/34o276-293i); go_component: GO:0005576 - extracellular region [Evidence IEA] AKAW2_20721A BUSCO:EOG09260K24; COG:J; EggNog:ENOG410PGHS; InterPro:IPR000504,IPR013979,IPR035979,IPR012677, IPR015943,IPR011400,IPR034363; PFAM:PF08662,PF00076; go_component: GO:0005852 - eukaryotic translation initiation factor 3 complex [Evidence IEA]; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0003723 - RNA binding [Evidence IEA]; go_function: GO:0003743 - translation initiation factor activity [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_function: GO:0031369 - translation initiation factor binding [Evidence IEA]; go_process: GO:0006413 - translational initiation [Evidence IEA] AKAW2_20722S COG:K; EggNog:ENOG410PNS5; InterPro:IPR014876; PFAM:PF08766 AKAW2_20723S BUSCO:EOG09261MOX; COG:O; EggNog:ENOG410PKRG; InterPro:IPR001841,IPR013087,IPR041888,IPR013083; PFAM:PF13920 AKAW2_20724A COG:L; EggNog:ENOG410PIRB; InterPro:IPR036187,IPR036678,IPR027417,IPR007696, IPR000432,IPR007861,IPR007860; PFAM:PF05188,PF05190,PF05192,PF00488; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0030983 - mismatched DNA binding [Evidence IEA]; go_process: GO:0006298 - mismatch repair [Evidence IEA] AKAW2_20725S COG:S; EggNog:ENOG410PGEI; InterPro:IPR012972,IPR036322,IPR015943,IPR001680, IPR019775,IPR020472,IPR017986; PFAM:PF12894,PF08154,PF00400; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_20726A COG:S; EggNog:ENOG410PU4H; SECRETED:SignalP(1-19) AKAW2_20727A COG:S; EggNog:ENOG410PHB7; InterPro:IPR038491,IPR021740,IPR037525; PFAM:PF11754 AKAW2_20728S COG:S; EggNog:ENOG410PW10; InterPro:IPR014870,IPR032514,IPR033433; PFAM:PF17168,PF16335,PF08760 AKAW2_20729S COG:K; EggNog:ENOG410Q2S4; InterPro:IPR036864,IPR021858,IPR001138; PFAM:PF00172; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_20730A COG:S; EggNog:ENOG410PS43; InterPro:IPR022024; PFAM:PF12223 AKAW2_20731A COG:S; EggNog:ENOG410PWVC; InterPro:IPR029675; TransMembrane:3 (i12-32o252-272i284-307o); go_component: GO:0000139 - Golgi membrane [Evidence IEA]; go_function: GO:0016757 - transferase activity, transferring glycosyl groups [Evidence IEA]; go_process: GO:0006506 - GPI anchor biosynthetic process [Evidence IEA] AKAW2_20732A COG:A; EggNog:ENOG410Q1QM; InterPro:IPR041677,IPR027417,IPR003593,IPR041679; PFAM:PF13245,PF13086,PF13087,PF13604; go_function: GO:0004386 - helicase activity [Evidence IEA] AKAW2_20733A COG:S; EggNog:ENOG410Q2U9 AKAW2_20734S COG:I; EggNog:ENOG410PK7T; InterPro:IPR001753,IPR029045,IPR014748; PFAM:PF00378; go_function: GO:0003824 - catalytic activity [Evidence IEA] AKAW2_20735A BUSCO:EOG09264HN5; COG:U; EggNog:ENOG410PMZU; InterPro:IPR013875; PFAM:PF08566; TransMembrane:2 (i113-133o153-181i); go_component: GO:0001405 - PAM complex, Tim23 associated import motor [Evidence IEA] AKAW2_20736A COG:W; EggNog:ENOG410PN85; InterPro:IPR006838; PFAM:PF04750; TransMembrane:6 (i21-42o62-83i95-114o126-151i158-178o202-223i); go_component: GO:0016021 - integral component of membrane [Evidence IEA] AKAW2_20737S COG:S; EggNog:ENOG410PJM7; InterPro:IPR036864,IPR021858,IPR001138; PFAM:PF00172,PF11951; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_20738S COG:S; EggNog:ENOG410PZDH AKAW2_20739S COG:G; EggNog:ENOG410Q4K3; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i61-78o106-124i131-153o159-179i191-214o226-247i296- 315o335-355i362-383o389-410i422-442o454-476i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_20740A COG:S; EggNog:ENOG410PY5B AKAW2_20741A SECRETED:SignalP(1-18) AKAW2_20742S COG:S; EggNog:ENOG410PQ79; InterPro:IPR025870,IPR029068; PFAM:PF13468 AKAW2_20743S COG:S; EggNog:ENOG410PQ8H; TransMembrane:1 (n21-32c37/38o152-175i) AKAW2_20744A COG:O; EggNog:ENOG410PJSB; InterPro:IPR002130,IPR036322,IPR020892,IPR015943, IPR029000,IPR001680,IPR017986; PFAM:PF00160,PF00400; go_function: GO:0003755 - peptidyl-prolyl cis-trans isomerase activity [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0000413 - protein peptidyl-prolyl isomerization [Evidence IEA]; go_process: GO:0006457 - protein folding [Evidence IEA] AKAW2_20745S COG:O; EggNog:ENOG410PH52; InterPro:IPR002423,IPR027410,IPR027413,IPR017998, IPR002194,IPR012716,IPR027409; PFAM:PF00118; go_component: GO:0005829 - cytosol [Evidence IEA]; go_component: GO:0005832 - chaperonin-containing T-complex [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0051082 - unfolded protein binding [Evidence IEA]; go_process: GO:0006457 - protein folding [Evidence IEA] AKAW2_20746S CAZy:GH76; COG:G; EggNog:ENOG410PFRH; InterPro:IPR005198,IPR008928,IPR014480; PFAM:PF03663; SECRETED:SignalP(1-24); TransMembrane:1 (n7-18c24/25o438-460i); go_function: GO:0008496 - mannan endo-1,6-alpha-mannosidase activity [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA]; go_process: GO:0016052 - carbohydrate catabolic process [Evidence IEA] AKAW2_20747A COG:E; EggNog:ENOG410PI4C; InterPro:IPR036038,IPR001544,IPR043131,IPR043132; PFAM:PF01063; TransMembrane:1 (i48-66o); go_function: GO:0003824 - catalytic activity [Evidence IEA] AKAW2_20748S BUSCO:EOG09260P2K; COG:T; EggNog:ENOG410PFXN; InterPro:IPR008271,IPR010513,IPR018391,IPR018997, IPR038357,IPR011047,IPR000719,IPR011009; PFAM:PF06479,PF00069,PF07714; SECRETED:SignalP(1-27); TransMembrane:1 (n10-21c25/26o507-525i); go_function: GO:0004540 - ribonuclease activity [Evidence IEA]; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006397 - mRNA processing [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_20749S BUSCO:EOG092621S9; COG:E; EggNog:ENOG410PHD8; InterPro:IPR022761,IPR000362,IPR024083,IPR020557, IPR008948,IPR029419,IPR009049; PFAM:PF14698,PF00206; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0004056 - argininosuccinate lyase activity [Evidence IEA]; go_process: GO:0042450 - arginine biosynthetic process via ornithine [Evidence IEA] AKAW2_20750A COG:S; EggNog:ENOG410PXM3 AKAW2_20751S COG:U; EggNog:ENOG410PHBS; InterPro:IPR032800,IPR010308,IPR040241; PFAM:PF06011,PF14558; SECRETED:SignalP(1-21); TransMembrane:7 (n5-16c21/22o320-342i369-389o395-421i458-478o484-504i516- 537o549-575i) AKAW2_20752S COG:G; EggNog:ENOG410PG45; InterPro:IPR035396,IPR008928,IPR012341; PFAM:PF17389; SECRETED:SignalP(1-17); go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_20753S CAZy:GH2; COG:G; EggNog:ENOG410PJPS; InterPro:IPR006102,IPR017853,IPR028829,IPR006104, IPR036156,IPR008979,IPR013783,IPR041351,IPR043534; PFAM:PF18368,PF00703; SECRETED:SignalP(1-19); go_component: GO:0005576 - extracellular region [Evidence IEA]; go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_function: GO:0052761 - exo-1,4-beta-D-glucosaminidase activity [Evidence IEA]; go_process: GO:0000272 - polysaccharide catabolic process [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_20754A COG:P; EggNog:ENOG410PFR8; InterPro:IPR017850,IPR000917,IPR024607; PFAM:PF00884; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0008484 - sulfuric ester hydrolase activity [Evidence IEA] AKAW2_20755A COG:G; EggNog:ENOG410PK8N; InterPro:IPR015943,IPR019405; PFAM:PF10282; SECRETED:SignalP(1-19); go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_20756S BUSCO:EOG09264EGS; COG:C; EggNog:ENOG410PPBK; InterPro:IPR036400,IPR018506,IPR001199; PFAM:PF00173; SECRETED:SignalP(1-26); go_function: GO:0020037 - heme binding [Evidence IEA] AKAW2_20757A COG:O; EggNog:ENOG410PQY3; InterPro:IPR001179; PFAM:PF00254; SECRETED:SignalP(1-20); go_function: GO:0003755 - peptidyl-prolyl cis-trans isomerase activity [Evidence IEA] AKAW2_20758A COG:P; EggNog:ENOG410PFZ2; InterPro:IPR004698,IPR003689; PFAM:PF02535; TransMembrane:8 (o30-50i62-84o104-123i190-217o223-246i258-278o290-314i326- 348o); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0005385 - zinc ion transmembrane transporter activity [Evidence IEA]; go_function: GO:0046873 - metal ion transmembrane transporter activity [Evidence IEA]; go_process: GO:0030001 - metal ion transport [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA]; go_process: GO:0071577 - zinc ion transmembrane transport [Evidence IEA] AKAW2_20759A InterPro:IPR016024 AKAW2_20760S InterPro:IPR036047; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_20761S COG:E; EggNog:ENOG410PHJ8; InterPro:IPR000172,IPR036188; go_function: GO:0016614 - oxidoreductase activity, acting on CH-OH group of donors [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_20762A COG:S; EggNog:ENOG410PXMM; InterPro:IPR018959; PFAM:PF09347; antiSMASH:Cluster_2.3 AKAW2_20763S COG:S; EggNog:ENOG410PM1K; InterPro:IPR036291,IPR008030; PFAM:PF05368; antiSMASH:Cluster_2.3 AKAW2_20764A COG:S; EggNog:ENOG410Q0BW; InterPro:IPR002110,IPR027417,IPR007111,IPR036770, IPR020683; PFAM:PF05729,PF12796,PF13401; antiSMASH:Cluster_2.3; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_20765A antiSMASH:Cluster_2.3 AKAW2_20766S COG:I; EggNog:ENOG410PVU8; InterPro:IPR008901; PFAM:PF05875; TransMembrane:4 (i48-66o72-90i111-135o155-176i); antiSMASH:Cluster_2.3; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0016811 - hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [Evidence IEA]; go_process: GO:0006672 - ceramide metabolic process [Evidence IEA] AKAW2_20767S COG:E; EggNog:ENOG410PGGM; InterPro:IPR038071,IPR002629; PFAM:PF01717; antiSMASH:Cluster_2.3; go_function: GO:0003871 - 5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0009086 - methionine biosynthetic process [Evidence IEA] AKAW2_20768S COG:Q; EggNog:ENOG410PNBC; InterPro:IPR036291,IPR002347; PFAM:PF08659,PF00106,PF13561; SMCOG1001:short-chain dehydrogenase/reductase SDR; TransMembrane:1 (o281-300i); antiSMASH:Cluster_2.3; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_20769S COG:Q; EggNog:ENOG410PHET; InterPro:IPR001128,IPR002401,IPR036396; PFAM:PF00067; SMCOG1034:cytochrome P450; TransMembrane:1 (n8-18c30/31o40-68i); antiSMASH:Cluster_2.3; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_20770A COG:Q; EggNog:ENOG410PVV8; InterPro:IPR016036,IPR016035,IPR016039,IPR018201, IPR042104,IPR014030,IPR011032,IPR013968,IPR013154, IPR001227,IPR032821,IPR014031,IPR006162,IPR014043, IPR020806,IPR020807,IPR020843,IPR020841,IPR029063, IPR036291,IPR013217; PFAM:PF16197,PF00109,PF08659,PF13489,PF13649, PF08240,PF00698,PF13847,PF13602,PF14765,PF00107,PF00106, PF08242,PF08241; SMCOG1022:Beta-ketoacyl synthase; antiSMASH:Cluster_2.3; go_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein] synthase activity [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0016740 - transferase activity [Evidence IEA]; go_function: GO:0016746 - transferase activity, transferring acyl groups [Evidence IEA]; go_function: GO:0031177 - phosphopantetheine binding [Evidence IEA]; go_process: GO:0006633 - fatty acid biosynthetic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_20771S COG:G; EggNog:ENOG410PK4Z; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; SMCOG1005:Drug resistance transporter, EmrB/QacA; TransMembrane:13 (i38-65o77-98i105-123o135-153i160-179o199-219i231-251o271- 296i308-328o334-354i366-387o407-425i446-466o); antiSMASH:Cluster_2.3; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_20772A COG:I; EggNog:ENOG410PJ2Y; InterPro:IPR036291,IPR013968,IPR036736,IPR009081; antiSMASH:Cluster_2.3 AKAW2_20773A COG:I; EggNog:ENOG410PMBD; InterPro:IPR016039,IPR018201,IPR020615,IPR014030, IPR014031,IPR020841; PFAM:PF00109,PF02801; SMCOG1022:Beta-ketoacyl synthase; antiSMASH:Cluster_2.3; go_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein] synthase activity [Evidence IEA]; go_function: GO:0016746 - transferase activity, transferring acyl groups [Evidence IEA]; go_function: GO:0016747 - transferase activity, transferring acyl groups other than amino-acyl groups [Evidence IEA]; go_process: GO:0006633 - fatty acid biosynthetic process [Evidence IEA] AKAW2_20774A COG:I; EggNog:ENOG410PHQT; InterPro:IPR036412,IPR006357,IPR006353,IPR023214; PFAM:PF13242,PF13344; antiSMASH:Cluster_2.3 AKAW2_20775S COG:C; EggNog:ENOG410PFQG; InterPro:IPR018170,IPR020471,IPR036812,IPR023210; PFAM:PF00248; SMCOG1039:aldo/keto reductase family oxidoreductase; antiSMASH:Cluster_2.3; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_20776A COG:S; EggNog:ENOG410PX8R AKAW2_20777A COG:I; EggNog:ENOG410Q2JU; InterPro:IPR001171,IPR018083; PFAM:PF01222; TransMembrane:8 (i12-33o74-94i115-136o148-169i247-266o286-304i316-335o429- 448i); go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0016628 - oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor [Evidence IEA]; go_process: GO:0016126 - sterol biosynthetic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_20778S COG:A; EggNog:ENOG410PPJM; InterPro:IPR036236,IPR013085,IPR040023,IPR003604; PFAM:PF06220; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0000398 - mRNA splicing, via spliceosome [Evidence IEA] AKAW2_20780S COG:S; EggNog:ENOG410PJQ9; InterPro:IPR036864,IPR001138; PFAM:PF00172; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_20781A COG:C; EggNog:ENOG410PFMM; InterPro:IPR006140,IPR036291,IPR006139,IPR029753, IPR029752; PFAM:PF03446,PF00389,PF02826; go_function: GO:0016616 - oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Evidence IEA]; go_function: GO:0051287 - NAD binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_20782A COG:S; EggNog:ENOG410PHHX; InterPro:IPR040194,IPR006767,IPR006768,IPR036265; PFAM:PF04677,PF04676 AKAW2_20783S BUSCO:EOG09263QH4; COG:L; EggNog:ENOG410PFDS; InterPro:IPR004130,IPR027417,IPR030230; PFAM:PF03029; go_function: GO:0003924 - GTPase activity [Evidence IEA] AKAW2_20784S COG:S; EggNog:ENOG410PP0W; TransMembrane:4 (o6-25i46-70o90-112i119-142o) AKAW2_20785S COG:S; EggNog:ENOG410Q20G; TransMembrane:1 (i9-31o) AKAW2_20786A COG:S; EggNog:ENOG410PZDS AKAW2_20787S COG:S; EggNog:ENOG410PPBA; InterPro:IPR024771 AKAW2_20788A COG:O; EggNog:ENOG410PIWC; InterPro:IPR036249,IPR040079,IPR036282,IPR010987, IPR004045; PFAM:PF13409,PF13417,PF13410,PF02798; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0006749 - glutathione metabolic process [Evidence IEA] AKAW2_20789A COG:E; EggNog:ENOG410PGSZ; InterPro:IPR002821,IPR008040,IPR003692; PFAM:PF01968,PF05378,PF02538; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_20790S COG:C,H; EggNog:ENOG410PIWS; InterPro:IPR036188,IPR002938; PFAM:PF01494; go_function: GO:0071949 - FAD binding [Evidence IEA] AKAW2_20791A COG:S; EggNog:ENOG410PMUI; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; TransMembrane:1 (o558-579i); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_20792S COG:G; EggNog:ENOG410PV8J; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:10 (i126-144o156-178i190-210o216-236i289-309o329-353i373- 391o403-425i437-456o468-488i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_20793A BUSCO:EOG09261DJC; COG:O; EggNog:ENOG410Q12F; InterPro:IPR036859,IPR000938,IPR001611,IPR032675; PFAM:PF01302; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_20794S BUSCO:EOG092653YS; COG:A; EggNog:ENOG410PI89; InterPro:IPR031781,IPR000690,IPR003604; PFAM:PF12874,PF16835; go_component: GO:0005634 - nucleus [Evidence IEA]; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA] AKAW2_20795A COG:T; EggNog:ENOG410PIR4; InterPro:IPR017441,IPR008271,IPR000961,IPR000719, IPR011009; PFAM:PF07714,PF00069; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0004674 - protein serine/threonine kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_20796S BUSCO:EOG09263XVS; COG:U; EggNog:ENOG410PGC5; InterPro:IPR021056; PFAM:PF11711; TransMembrane:1 (o47-64i) AKAW2_20797A BUSCO:EOG09260J97; COG:B; EggNog:ENOG410PG4X; InterPro:IPR011990,IPR019734,IPR021183,IPR013026; PFAM:PF13181,PF12569; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_20798A COG:S; EggNog:ENOG410Q2HU; InterPro:IPR016805,IPR019171; PFAM:PF09774 AKAW2_20799S COG:L; EggNog:ENOG410PJBJ; InterPro:IPR012319,IPR010979,IPR015886,IPR035937; PFAM:PF01149,PF06831; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0003684 - damaged DNA binding [Evidence IEA]; go_function: GO:0003906 - DNA-(apurinic or apyrimidinic site) endonuclease activity [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_function: GO:0016799 - hydrolase activity, hydrolyzing N-glycosyl compounds [Evidence IEA]; go_function: GO:0019104 - DNA N-glycosylase activity [Evidence IEA]; go_process: GO:0006284 - base-excision repair [Evidence IEA] AKAW2_20800A COG:S; EggNog:ENOG410PV0H; InterPro:IPR019261,IPR043472,IPR012664; PFAM:PF10021 AKAW2_20801S BUSCO:EOG09261P7G; COG:Y; EggNog:ENOG410PGEE; InterPro:IPR004108,IPR009016; PFAM:PF02906 AKAW2_20803S COG:K; EggNog:ENOG410PR3T; InterPro:IPR039747,IPR006591,IPR029040; PFAM:PF03604; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0003899 - DNA-directed 5'-3' RNA polymerase activity [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA] AKAW2_20802A BUSCO:EOG09262N10; COG:E; EggNog:ENOG410PH4I; InterPro:IPR036320,IPR017459,IPR000312,IPR035902; PFAM:PF02885,PF00591; go_function: GO:0016757 - transferase activity, transferring glycosyl groups [Evidence IEA] AKAW2_20804S COG:S; EggNog:ENOG410PJEZ; InterPro:IPR043141,IPR001790; go_process: GO:0042254 - ribosome biogenesis [Evidence IEA] AKAW2_20805A COG:T; EggNog:ENOG410PKC3; InterPro:IPR000909,IPR017946; PFAM:PF00388; go_function: GO:0008081 - phosphoric diester hydrolase activity [Evidence IEA]; go_process: GO:0006629 - lipid metabolic process [Evidence IEA] AKAW2_20806S COG:S; EggNog:ENOG410Q2M0 AKAW2_20807A COG:G; EggNog:ENOG410PNMQ; InterPro:IPR027417,IPR006001,IPR031322; PFAM:PF01202,PF13671; go_function: GO:0016301 - kinase activity [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_20808S BUSCO:EOG092632FC; COG:U; EggNog:ENOG410PHXC; InterPro:IPR028934,IPR014752; PFAM:PF03643; go_process: GO:0006886 - intracellular protein transport [Evidence IEA] AKAW2_20809A BUSCO:EOG092604MJ; COG:I; EggNog:ENOG410PGDZ; InterPro:IPR016024,IPR026829,IPR032817,IPR032629, IPR032691; PFAM:PF12783,PF16213; go_process: GO:0015031 - protein transport [Evidence IEA] AKAW2_20810S BUSCO:EOG09264UD3; COG:O; EggNog:ENOG410PMX7; InterPro:IPR016135,IPR000608; PFAM:PF00179 AKAW2_20811S COG:S; EggNog:ENOG410PSES; InterPro:IPR008011; PFAM:PF05347 AKAW2_20812A BUSCO:EOG09265K60; COG:S; EggNog:ENOG410PPZ9; InterPro:IPR016135,IPR040213,IPR006575; PFAM:PF05773; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_20813S COG:S; EggNog:ENOG410PI0V; InterPro:IPR011990,IPR019734,IPR013026; PFAM:PF13181,PF13174; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_20814S COG:B; EggNog:ENOG410PGKD; InterPro:IPR029035,IPR003000,IPR026590,IPR026591; PFAM:PF02146; go_function: GO:0070403 - NAD+ binding [Evidence IEA] AKAW2_20815S BUSCO:EOG09262GNE; COG:L; EggNog:ENOG410PFNQ; InterPro:IPR002052,IPR029063,IPR016691,IPR000241; PFAM:PF01170; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0008168 - methyltransferase activity [Evidence IEA]; go_process: GO:0032259 - methylation [Evidence IEA] AKAW2_20816A COG:S; EggNog:ENOG410PXRY; InterPro:IPR011146,IPR001310,IPR019808,IPR036265; PFAM:PF11969,PF01230; go_function: GO:0003824 - catalytic activity [Evidence IEA] AKAW2_20817A COG:D; EggNog:ENOG410PGW0; InterPro:IPR036915,IPR006671,IPR004367,IPR039361, IPR013763; PFAM:PF02984,PF00134 AKAW2_20818S BUSCO:EOG09262X31; COG:J; EggNog:ENOG410PFKQ; InterPro:IPR022669,IPR008991,IPR022666,IPR014726, IPR002171,IPR012340,IPR014722; PFAM:PF03947,PF00181; go_component: GO:0005840 - ribosome [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_process: GO:0006412 - translation [Evidence IEA] AKAW2_20819S COG:K; EggNog:ENOG410PMB5; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_20820A COG:S; EggNog:ENOG410PJKX; InterPro:IPR024977,IPR040132,IPR015943,IPR001680, IPR019775,IPR020472,IPR036322,IPR017986; PFAM:PF12894,PF00400; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0006406 - mRNA export from nucleus [Evidence IEA] AKAW2_20821S COG:A; EggNog:ENOG410PPRK; InterPro:IPR013893; PFAM:PF08584 AKAW2_20822A COG:L; EggNog:ENOG410PHGW; InterPro:IPR011604,IPR022765,IPR041677,IPR014808, IPR026851,IPR027417,IPR041679; PFAM:PF08696,PF13245,PF13087,PF12705,PF01930, PF13604; go_function: GO:0004386 - helicase activity [Evidence IEA]; go_function: GO:0017108 - 5'-flap endonuclease activity [Evidence IEA]; go_function: GO:0017116 - single-stranded DNA helicase activity [Evidence IEA]; go_process: GO:0033567 - DNA replication, Okazaki fragment processing [Evidence IEA] AKAW2_20823S COG:S; EggNog:ENOG410PQQZ; InterPro:IPR019329; PFAM:PF10183; TransMembrane:1 (o60-78i) AKAW2_20824A COG:E; EggNog:ENOG410PG53; InterPro:IPR036526,IPR003010; PFAM:PF00795; go_process: GO:0006807 - nitrogen compound metabolic process [Evidence IEA] AKAW2_20825S BUSCO:EOG09260AQB; COG:J; EggNog:ENOG410PHAG; InterPro:IPR001900,IPR012340,IPR033770,IPR033771, IPR022966,IPR041505,IPR029060,IPR002716; PFAM:PF17216,PF17215,PF17876,PF13638,PF00773, PF17849; go_function: GO:0003723 - RNA binding [Evidence IEA]; go_function: GO:0004540 - ribonuclease activity [Evidence IEA] AKAW2_20826A COG:G; EggNog:ENOG410PJKR; InterPro:IPR011701,IPR036259; PFAM:PF07690; TransMembrane:11 (o94-114i126-145o151-172i184-203o215-235i259-281o293- 312i324-343o349-372i384-404o416-436i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_20827S COG:T,Z; EggNog:ENOG410PHUY; InterPro:IPR001781; PFAM:PF00412 AKAW2_20828S COG:G; EggNog:ENOG410PJKB; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:11 (o80-102i109-128o134-157i169-191o203-225i278-296o316- 334i346-366o372-392i404-421o433-458i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_20829A COG:J; EggNog:ENOG410PFK1; InterPro:IPR003358,IPR025763,IPR029063; go_function: GO:0008176 - tRNA (guanine-N7-)-methyltransferase activity [Evidence IEA]; go_process: GO:0006400 - tRNA modification [Evidence IEA] AKAW2_20830S COG:U; EggNog:ENOG410PPAC; InterPro:IPR014041,IPR008570,IPR036390,IPR036388; PFAM:PF05871; go_component: GO:0000814 - ESCRT II complex [Evidence IEA]; go_process: GO:0071985 - multivesicular body sorting pathway [Evidence IEA] AKAW2_20831A COG:L; EggNog:ENOG410Q18P; InterPro:IPR001357,IPR036420; PFAM:PF00533,PF16770,PF12738 AKAW2_20832S COG:S; EggNog:ENOG410PJ7E; InterPro:IPR000073,IPR029058; MEROPS:MER0209971; PFAM:PF12697,PF12146 AKAW2_20833A COG:I; EggNog:ENOG410PJEF; InterPro:IPR008901; PFAM:PF05875; TransMembrane:7 (o43-61i73-91o103-120i127-146o152-170i218-238o265-285i); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0016811 - hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [Evidence IEA]; go_process: GO:0006672 - ceramide metabolic process [Evidence IEA] AKAW2_20834S COG:C; EggNog:ENOG410PJED; InterPro:IPR018108,IPR030847,IPR023395; PFAM:PF00153; go_component: GO:0005743 - mitochondrial inner membrane [Evidence IEA]; go_function: GO:0015187 - glycine transmembrane transporter activity [Evidence IEA]; go_process: GO:1904983 - glycine import into mitochondrion [Evidence IEA] AKAW2_20835A COG:S; EggNog:ENOG410PT1M AKAW2_20836A COG:S; EggNog:ENOG410Q1B6; InterPro:IPR039020; TransMembrane:7 (o13-36i48-68o74-95i115-135o141-161i173-193o205-227i) AKAW2_20837A COG:S; EggNog:ENOG410Q1B6; SECRETED:SignalP(1-19) AKAW2_20838S COG:J; EggNog:ENOG410PGET AKAW2_20839S COG:S; EggNog:ENOG410PPYX; InterPro:IPR001077,IPR036388,IPR016461,IPR029063, IPR036390; PFAM:PF00891; go_function: GO:0008168 - methyltransferase activity [Evidence IEA]; go_function: GO:0008171 - O-methyltransferase activity [Evidence IEA] AKAW2_20840A COG:S; EggNog:ENOG410PU56; InterPro:IPR036610,IPR008914,IPR035810; PFAM:PF01161; SECRETED:SignalP(1-30) AKAW2_20841A COG:O; EggNog:ENOG410PQNS; InterPro:IPR009053,IPR002777; PFAM:PF01920; go_component: GO:0016272 - prefoldin complex [Evidence IEA]; go_function: GO:0051082 - unfolded protein binding [Evidence IEA]; go_process: GO:0006457 - protein folding [Evidence IEA] AKAW2_20842A COG:Q; EggNog:ENOG410PH6A; InterPro:IPR026992,IPR027443,IPR005123; PFAM:PF03171,PF14226; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_20843S COG:S; EggNog:ENOG410PSFG; SECRETED:SignalP(1-18) AKAW2_20844S COG:S; EggNog:ENOG410PRC8; SECRETED:SignalP(1-25); TransMembrane:1 (n6-17c25/26o283-303i) AKAW2_20845S BUSCO:EOG09263Q8J; COG:S; EggNog:ENOG410PFZX; InterPro:IPR016024,IPR011989,IPR007216; PFAM:PF04078; go_component: GO:0030014 - CCR4-NOT complex [Evidence IEA]; go_process: GO:0006402 - mRNA catabolic process [Evidence IEA] AKAW2_20846S COG:S; EggNog:ENOG410PHJ2; InterPro:IPR028938,IPR019787,IPR019786,IPR011011, IPR001965,IPR013083; PFAM:PF00628; go_component: GO:0031213 - RSF complex [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_20847S COG:B; EggNog:ENOG410PQ5M; InterPro:IPR009071,IPR036910; PFAM:PF00505 AKAW2_20848A COG:S; EggNog:ENOG410PSSX AKAW2_20849S BUSCO:EOG092648K5; COG:L; EggNog:ENOG410PJ86; InterPro:IPR036224,IPR021151,IPR005339; PFAM:PF05916; go_component: GO:0000811 - GINS complex [Evidence IEA]; go_process: GO:0006260 - DNA replication [Evidence IEA] AKAW2_20850S BUSCO:EOG09260A27; COG:P; EggNog:ENOG410PG8Q; InterPro:IPR002645,IPR001902,IPR000595,IPR018490, IPR036513,IPR014710,IPR011547; PFAM:PF00916,PF00027,PF01740; TransMembrane:10 (o277-298i310-332o365-387i399-421o441-463i470-487o537- 559i571-591o611-643i664-696o); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0008271 - secondary active sulfate transmembrane transporter activity [Evidence IEA]; go_function: GO:0015116 - sulfate transmembrane transporter activity [Evidence IEA]; go_process: GO:0008272 - sulfate transport [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_20851S SECRETED:SignalP(1-25); TransMembrane:1 (n10-20c25/26o41-58i) AKAW2_20852S COG:S; EggNog:ENOG410PJRW; InterPro:IPR001849,IPR039483,IPR039712; PFAM:PF15406,PF00169 AKAW2_20853S COG:K; EggNog:ENOG410PP0E; InterPro:IPR004827; PFAM:PF07716; go_function: GO:0003700 - DNA-binding transcription factor activity [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_20854A COG:E; EggNog:ENOG410PIH6; InterPro:IPR029055,IPR001962,IPR017932,IPR014729; PFAM:PF13537; go_function: GO:0004066 - asparagine synthase (glutamine-hydrolyzing) activity [Evidence IEA]; go_process: GO:0006529 - asparagine biosynthetic process [Evidence IEA] AKAW2_20855S BUSCO:EOG0926499W; COG:U; EggNog:ENOG410PIQF; InterPro:IPR041804,IPR009060,IPR003892,IPR041545, IPR003123,IPR037191; PFAM:PF18151,PF02845,PF02204; go_function: GO:0005515 - protein binding [Evidence IEA]; go_function: GO:0043130 - ubiquitin binding [Evidence IEA] AKAW2_20856A COG:S; EggNog:ENOG410PXZG; InterPro:IPR032675 AKAW2_20857S COG:S; EggNog:ENOG410PS2A; InterPro:IPR000519; TransMembrane:1 (i39-67o) AKAW2_20859S SECRETED:SignalP(1-17) AKAW2_20862S COG:S; EggNog:ENOG410PHKX; InterPro:IPR008217; PFAM:PF01988; TransMembrane:3 (i207-231o237-256i277-298o); go_function: GO:0005384 - manganese ion transmembrane transporter activity [Evidence IEA]; go_process: GO:0030026 - cellular manganese ion homeostasis [Evidence IEA] AKAW2_20863A COG:S; EggNog:ENOG410PN26; InterPro:IPR025255; PFAM:PF13875 AKAW2_20864S COG:S; EggNog:ENOG410Q110; InterPro:IPR001279,IPR036866; PFAM:PF00753 AKAW2_20865A COG:S; EggNog:ENOG410PN5H; InterPro:IPR013942; PFAM:PF08633; go_component: GO:0016592 - mediator complex [Evidence IEA]; go_function: GO:0003712 - transcription coregulator activity [Evidence IEA]; go_process: GO:0006357 - regulation of transcription by RNA polymerase II [Evidence IEA] AKAW2_20866A COG:K; EggNog:ENOG410PHFN; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_20867S COG:K; EggNog:ENOG410PHSZ; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_20868S COG:S; EggNog:ENOG410PIQQ; InterPro:IPR027842,IPR017943; PFAM:PF14613; go_function: GO:0008289 - lipid binding [Evidence IEA] AKAW2_20869A BUSCO:EOG09261D4D; COG:F; EggNog:ENOG410PH6H; InterPro:IPR033747,IPR011761,IPR016185,IPR035893, IPR000031,IPR005875,IPR003135,IPR016301,IPR013815, IPR011054,IPR040686; PFAM:PF02786,PF02222,PF00731,PF17769; go_function: GO:0004638 - phosphoribosylaminoimidazole carboxylase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0046872 - metal ion binding [Evidence IEA]; go_process: GO:0006189 - 'de novo' IMP biosynthetic process [Evidence IEA] AKAW2_20870S COG:S; EggNog:ENOG410PQDV; InterPro:IPR015267; go_component: GO:0030289 - protein phosphatase 4 complex [Evidence IEA]; go_function: GO:0019888 - protein phosphatase regulator activity [Evidence IEA] AKAW2_20871A BUSCO:EOG092609YT; COG:P; EggNog:ENOG410PG9C; InterPro:IPR018303,IPR023298,IPR023299,IPR036163, IPR036412,IPR001757,IPR017969,IPR006121,IPR006122, IPR027256,IPR008250,IPR023214; PFAM:PF00403,PF00702,PF00122; TransMembrane:8 (i381-403o415-435i456-480o486-505i670-691o711-733i1055- 1078o1084-1106i); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0000166 - nucleotide binding [Evidence IEA]; go_function: GO:0005507 - copper ion binding [Evidence IEA]; go_function: GO:0019829 - ATPase-coupled cation transmembrane transporter activity [Evidence IEA]; go_function: GO:0046872 - metal ion binding [Evidence IEA]; go_process: GO:0006812 - cation transport [Evidence IEA]; go_process: GO:0030001 - metal ion transport [Evidence IEA] AKAW2_20872S COG:O,T; EggNog:ENOG410PQ0D; InterPro:IPR000717; PFAM:PF01399 AKAW2_20873A COG:S; EggNog:ENOG410PI0N; InterPro:IPR016137,IPR036305; PFAM:PF00615; TransMembrane:3 (o261-284i291-311o346-367i) AKAW2_20875S COG:Q; EggNog:ENOG410PW7K; InterPro:IPR036291,IPR002347; PFAM:PF08659,PF00106,PF13561; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_20874A COG:B; EggNog:ENOG410PFEX; InterPro:IPR036427,IPR001487,IPR037800,IPR016181, IPR000182,IPR018359; PFAM:PF00439,PF13673,PF00583; go_function: GO:0004402 - histone acetyltransferase activity [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_function: GO:0008080 - N-acetyltransferase activity [Evidence IEA] AKAW2_20876S COG:S; EggNog:ENOG410Q23J; InterPro:IPR007915; PFAM:PF05251; TransMembrane:2 (o25-44i51-76o); go_component: GO:0034998 - oligosaccharyltransferase I complex [Evidence IEA]; go_process: GO:0006487 - protein N-linked glycosylation [Evidence IEA] AKAW2_20877S BUSCO:EOG092648O6; COG:L; EggNog:ENOG410PNKT; InterPro:IPR003021; PFAM:PF02144; go_process: GO:0000077 - DNA damage checkpoint [Evidence IEA] AKAW2_20878A BUSCO:EOG092606WZ; COG:L; EggNog:ENOG410PG7Q; InterPro:IPR027417,IPR004584,IPR038729; PFAM:PF13476,PF13175,PF13558; go_component: GO:0005634 - nucleus [Evidence IEA]; go_component: GO:0030870 - Mre11 complex [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA]; go_process: GO:0000723 - telomere maintenance [Evidence IEA]; go_process: GO:0006281 - DNA repair [Evidence IEA] AKAW2_20879S SECRETED:SignalP(1-23) AKAW2_20880S COG:K; EggNog:ENOG410PKDR; InterPro:IPR000679,IPR035965,IPR013088,IPR013655, IPR000014; PFAM:PF08447,PF00320; go_function: GO:0005515 - protein binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_function: GO:0043565 - sequence-specific DNA binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_20881A COG:E; EggNog:ENOG410Q17A; InterPro:IPR036412,IPR006384,IPR023214; PFAM:PF12710; go_function: GO:0016791 - phosphatase activity [Evidence IEA] AKAW2_20882S COG:J; EggNog:ENOG410PJPR; InterPro:IPR014816,IPR029063; go_component: GO:0031515 - tRNA (m1A) methyltransferase complex [Evidence IEA]; go_function: GO:0016429 - tRNA (adenine-N1-)-methyltransferase activity [Evidence IEA]; go_process: GO:0030488 - tRNA methylation [Evidence IEA] AKAW2_20883A BUSCO:EOG09260WGT; COG:K; EggNog:ENOG410PHFH; InterPro:IPR001611,IPR005135,IPR003591,IPR032675, IPR036691; PFAM:PF03372,PF12799,PF13855; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_20884S COG:S; EggNog:ENOG410PKEG; InterPro:IPR029063,IPR041698; PFAM:PF08241,PF13649 AKAW2_20885A COG:S; EggNog:ENOG410PTXK; PFAM:PF13233,PF05347 AKAW2_20886S COG:S; EggNog:ENOG410Q0QJ AKAW2_20887S COG:S; EggNog:ENOG410PMXZ; PFAM:PF13279 AKAW2_20888S COG:S; EggNog:ENOG410PJR6; TransMembrane:3 (i159-180o212-233i321-339o) AKAW2_20889A COG:S; EggNog:ENOG410PSA4; InterPro:IPR012349,IPR002563; PFAM:PF01613; go_function: GO:0010181 - FMN binding [Evidence IEA] AKAW2_20891S COG:J; EggNog:ENOG410PQSV; InterPro:IPR034600; go_component: GO:0005762 - mitochondrial large ribosomal subunit [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_process: GO:0032543 - mitochondrial translation [Evidence IEA] AKAW2_20890A COG:U; EggNog:ENOG410PI2Z; InterPro:IPR027267,IPR035803,IPR001683,IPR036871, IPR015404; PFAM:PF09325,PF00787; go_function: GO:0035091 - phosphatidylinositol binding [Evidence IEA] AKAW2_20892A COG:G; EggNog:ENOG410PHCC; InterPro:IPR036409,IPR017714,IPR027514,IPR001303; PFAM:PF00596; go_component: GO:0005737 - cytoplasm [Evidence IEA]; go_function: GO:0046872 - metal ion binding [Evidence IEA]; go_process: GO:0019509 - L-methionine salvage from methylthioadenosine [Evidence IEA] AKAW2_20893S COG:O; EggNog:ENOG410PFWS; InterPro:IPR001580,IPR009033,IPR018124,IPR013320; PFAM:PF00262; SECRETED:SignalP(1-23); TransMembrane:1 (n5-15c23/24o494-515i); go_component: GO:0005783 - endoplasmic reticulum [Evidence IEA]; go_function: GO:0005509 - calcium ion binding [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_function: GO:0051082 - unfolded protein binding [Evidence IEA]; go_process: GO:0006457 - protein folding [Evidence IEA] AKAW2_20894S COG:C; EggNog:ENOG410PFAG; InterPro:IPR015590,IPR016162,IPR016160,IPR016161, IPR010061,IPR016163; PFAM:PF00171; go_function: GO:0004491 - methylmalonate-semialdehyde dehydrogenase (acylating) activity [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0016620 - oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_20895A COG:S; EggNog:ENOG410PN3S AKAW2_20896S COG:Z; EggNog:ENOG410PGGR; InterPro:IPR028133; PFAM:PF04912; go_component: GO:0005869 - dynactin complex [Evidence IEA]; go_process: GO:0007017 - microtubule-based process [Evidence IEA] AKAW2_20897A COG:S; EggNog:ENOG410PFK3; InterPro:IPR011990,IPR027417,IPR007111,IPR000433, IPR042621; PFAM:PF05729; SECRETED:SignalP(1-24); go_function: GO:0005515 - protein binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA] AKAW2_20899A CAZy:GT22; COG:G; EggNog:ENOG410PI08; InterPro:IPR005599,IPR039485; PFAM:PF03901; SECRETED:SignalP(1-20); TransMembrane:8 (n5-20c24/25o97-115i127-144o180-208i220-242o278-298i305- 322o328-350i357-382o); go_component: GO:0005788 - endoplasmic reticulum lumen [Evidence IEA]; go_function: GO:0016757 - transferase activity, transferring glycosyl groups [Evidence IEA]; go_function: GO:0052824 - dolichyl-pyrophosphate Man7GlcNAc2 alpha-1,6-mannosyltransferase activity [Evidence IEA]; go_process: GO:0006488 - dolichol-linked oligosaccharide biosynthetic process [Evidence IEA] AKAW2_20900S COG:U; EggNog:ENOG410PRZ5; InterPro:IPR013880; PFAM:PF08571; TransMembrane:2 (o6-23i65-84o) AKAW2_20901A COG:O; EggNog:ENOG410PG83; InterPro:IPR038765,IPR001394,IPR018200,IPR028889; MEROPS:MER0014642; PFAM:PF13423,PF00443; go_function: GO:0004843 - thiol-dependent ubiquitin-specific protease activity [Evidence IEA]; go_process: GO:0006511 - ubiquitin-dependent protein catabolic process [Evidence IEA]; go_process: GO:0016579 - protein deubiquitination [Evidence IEA] AKAW2_20902S COG:J; EggNog:ENOG410PHWW; InterPro:IPR036621,IPR006195,IPR041715,IPR015807, IPR004154,IPR033656; PFAM:PF03129,PF13393; go_function: GO:0004821 - histidine-tRNA ligase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006427 - histidyl-tRNA aminoacylation [Evidence IEA] AKAW2_20903A BUSCO:EOG09261031; COG:H; EggNog:ENOG410PFEE; InterPro:IPR018168,IPR036188,IPR002938,IPR000689, IPR010971; PFAM:PF01494; go_function: GO:0004497 - monooxygenase activity [Evidence IEA]; go_function: GO:0016709 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_function: GO:0071949 - FAD binding [Evidence IEA]; go_process: GO:0006744 - ubiquinone biosynthetic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_20904S COG:S; EggNog:ENOG410Q1B0 AKAW2_20905A BUSCO:EOG09261PNZ; COG:U; EggNog:ENOG410PFJX; InterPro:IPR027267,IPR001683,IPR036871,IPR015404; PFAM:PF09325,PF00787; go_function: GO:0035091 - phosphatidylinositol binding [Evidence IEA] AKAW2_20906A BUSCO:EOG09260J8F; COG:O; EggNog:ENOG410PF8E; InterPro:IPR023828,IPR002884,IPR000209,IPR034182, IPR008979,IPR022398,IPR015500,IPR036852; MEROPS:MER0000364; PFAM:PF01483,PF00082; SECRETED:SignalP(1-19); TransMembrane:1 (n3-14c19/20o737-759i); go_function: GO:0004252 - serine-type endopeptidase activity [Evidence IEA]; go_function: GO:0008236 - serine-type peptidase activity [Evidence IEA]; go_process: GO:0006508 - proteolysis [Evidence IEA] AKAW2_20907A COG:C; EggNog:ENOG410PFFH; InterPro:IPR027545,IPR036188,IPR002938; PFAM:PF01494; TransMembrane:1 (n6-17c22/23o452-473i); go_function: GO:0004502 - kynurenine 3-monooxygenase activity [Evidence IEA]; go_function: GO:0071949 - FAD binding [Evidence IEA]; go_process: GO:0006569 - tryptophan catabolic process [Evidence IEA]; go_process: GO:0019805 - quinolinate biosynthetic process [Evidence IEA] AKAW2_20908A COG:G; EggNog:ENOG410PUEZ; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i70-94o106-129i136-156o162-183i195-214o226-246i266- 284o296-316i337-359o371-396i403-422o506-526i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_20909S COG:S; EggNog:ENOG410PGCZ; InterPro:IPR018946,IPR043904 AKAW2_20910S BUSCO:EOG0926386D; COG:O; EggNog:ENOG410PF9Q; InterPro:IPR036188,IPR005982,IPR008255,IPR023753; PFAM:PF13738,PF00070,PF07992; go_component: GO:0005737 - cytoplasm [Evidence IEA]; go_function: GO:0004791 - thioredoxin-disulfide reductase activity [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0019430 - removal of superoxide radicals [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_20911A COG:U; EggNog:ENOG410PINQ; InterPro:IPR032816; PFAM:PF09335; TransMembrane:5 (o82-109i121-139o159-180i235-254o274-295i) AKAW2_20912S COG:L; EggNog:ENOG410QE6U; InterPro:IPR002625,IPR013899,IPR036063,IPR000571, IPR036855; PFAM:PF01713,PF14608,PF08590; go_function: GO:0046872 - metal ion binding [Evidence IEA] AKAW2_20913A COG:G; EggNog:ENOG410PHU5; InterPro:IPR015813,IPR005000,IPR040442,IPR011206; PFAM:PF03328; go_function: GO:0003824 - catalytic activity [Evidence IEA] AKAW2_20914S COG:U; EggNog:ENOG410PK6X; InterPro:IPR008564; PFAM:PF05832; TransMembrane:5 (i21-41o47-66i111-132o138-157i169-191o); go_component: GO:0016021 - integral component of membrane [Evidence IEA] AKAW2_20915A COG:C; EggNog:ENOG410PNQE; InterPro:IPR016166,IPR016169,IPR036318,IPR006094; PFAM:PF01565; SECRETED:SignalP(1-16); go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_function: GO:0071949 - FAD binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_20916S COG:H; EggNog:ENOG410PHQP; InterPro:IPR000860,IPR036803,IPR022419,IPR022418, IPR022417; PFAM:PF03900,PF01379; go_function: GO:0004418 - hydroxymethylbilane synthase activity [Evidence IEA]; go_process: GO:0018160 - peptidyl-pyrromethane cofactor linkage [Evidence IEA]; go_process: GO:0033014 - tetrapyrrole biosynthetic process [Evidence IEA] AKAW2_20917S COG:S; EggNog:ENOG410PUNS; InterPro:IPR001810; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_20919A COG:S; EggNog:ENOG410PIGJ; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; TransMembrane:1 (o538-560i); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_20920S COG:Q; EggNog:ENOG410PV0G; InterPro:IPR001128,IPR017972,IPR002401,IPR036396; PFAM:PF00067; TransMembrane:1 (i7-30o); go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_20921S COG:U; EggNog:ENOG410QDWV; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i84-102o122-140i152-174o180-199i211-234o240-259i310- 328o348-370i391-412o424-446i453-475o487-508i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_20922S COG:A; EggNog:ENOG410PK44; InterPro:IPR041670,IPR025836,IPR001878,IPR036875; PFAM:PF15288,PF00098; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA] AKAW2_20923A COG:Q; EggNog:ENOG410PFN7; InterPro:IPR027417,IPR010929,IPR003439,IPR013525; PFAM:PF01061,PF00005,PF06422; TransMembrane:12 (i386-405o411-433i472-489o495-515i527-546o633-655i1039- 1058o1070-1092i1113-1136o1156-1174i1181-1197o1302-1322i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0042626 - ATPase-coupled transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_20925A COG:S; EggNog:ENOG410QEIF AKAW2_20928S COG:G; EggNog:ENOG410PV9J; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:11 (n4-17c25/26o35-53i65-82o94-112i124-147o153-173i243- 266o286-304i338-358o370-389i401-424o430-451i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_20929S COG:G; EggNog:ENOG410PFEN; InterPro:IPR005829,IPR005828,IPR003663,IPR036259, IPR020846; PFAM:PF00083,PF07690; TransMembrane:8 (i75-98o104-124i160-179o191-214i347-367o373-400i412- 434o440-461i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_20930S COG:G; EggNog:ENOG410PH49; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i56-74o94-113i133-152o158-179i191-209o221-243i308- 330o342-360i372-392o404-424i436-459o479-499i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_20931A BUSCO:EOG09262MXH; COG:E; EggNog:ENOG410PI17; InterPro:IPR014746,IPR036651,IPR008147,IPR008146, IPR027302,IPR027303; PFAM:PF03951; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0004356 - glutamate-ammonia ligase activity [Evidence IEA]; go_process: GO:0006542 - glutamine biosynthetic process [Evidence IEA]; go_process: GO:0006807 - nitrogen compound metabolic process [Evidence IEA] AKAW2_20932A COG:S; EggNog:ENOG410PJZ4; InterPro:IPR019680; PFAM:PF10744; go_component: GO:0016592 - mediator complex [Evidence IEA]; go_function: GO:0003712 - transcription coregulator activity [Evidence IEA]; go_process: GO:0006357 - regulation of transcription by RNA polymerase II [Evidence IEA] AKAW2_20933S COG:S; EggNog:ENOG410PPIB AKAW2_20934A COG:S; EggNog:ENOG410PK5Y; InterPro:IPR003738,IPR036590; PFAM:PF02586; go_function: GO:0003697 - single-stranded DNA binding [Evidence IEA]; go_process: GO:0006974 - cellular response to DNA damage stimulus [Evidence IEA]; go_process: GO:0018142 - protein-DNA covalent cross-linking [Evidence IEA] AKAW2_20935A BUSCO:EOG092636T6; COG:T; EggNog:ENOG410PIEY; InterPro:IPR036322,IPR015943,IPR001680,IPR019775, IPR020472,IPR017986; PFAM:PF00400; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_20936A COG:U; EggNog:ENOG410PPQH; InterPro:IPR028882,IPR005631,IPR036714; PFAM:PF03937; go_component: GO:0005739 - mitochondrion [Evidence IEA]; go_process: GO:0018293 - protein-FAD linkage [Evidence IEA] AKAW2_20937A COG:U; EggNog:ENOG410PKXU; InterPro:IPR015720,IPR009038; PFAM:PF01105; SECRETED:SignalP(1-25); TransMembrane:1 (n10-20c25/26o188-208i) AKAW2_20938A COG:S; EggNog:ENOG410PGR2; InterPro:IPR016641; go_component: GO:0005854 - nascent polypeptide-associated complex [Evidence IEA] AKAW2_20939A COG:S; EggNog:ENOG410PZ72 AKAW2_20940S TransMembrane:1 (i54-81o) AKAW2_20941S COG:S; EggNog:ENOG410PS4B; InterPro:IPR040112 AKAW2_20942A COG:S; EggNog:ENOG410PQ2I; InterPro:IPR007763; PFAM:PF05071; go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0008137 - NADH dehydrogenase (ubiquinone) activity [Evidence IEA]; go_function: GO:0009055 - electron transfer activity [Evidence IEA] AKAW2_20943S COG:Z; EggNog:ENOG410PGZF; InterPro:IPR003096,IPR001715,IPR036872; PFAM:PF00307; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_20944A COG:S; EggNog:ENOG410PM21 AKAW2_20945S COG:P; EggNog:ENOG410PFYA; InterPro:IPR004923; PFAM:PF03239; TransMembrane:5 (o19-40i78-99o111-130i137-157o227-246i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0033573 - high-affinity iron permease complex [Evidence IEA]; go_function: GO:0005381 - iron ion transmembrane transporter activity [Evidence IEA]; go_process: GO:0034755 - iron ion transmembrane transport [Evidence IEA] AKAW2_20947A COG:S; EggNog:ENOG410PKSA; InterPro:IPR011009; TransMembrane:1 (o614-632i) AKAW2_20948A BUSCO:EOG09264F60; COG:S; EggNog:ENOG410PI6A; InterPro:IPR007203; PFAM:PF04061; TransMembrane:4 (i47-67o73-91i124-140o146-164i); go_component: GO:0005789 - endoplasmic reticulum membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA] AKAW2_20950S COG:S; EggNog:ENOG410QEDP; InterPro:IPR001878; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA] AKAW2_20949A COG:S; EggNog:ENOG410PKDS; InterPro:IPR036412,IPR041492,IPR023214; PFAM:PF13242,PF13419 AKAW2_20951S COG:S; EggNog:ENOG410Q2EA; TransMembrane:1 (o20-40i) AKAW2_20952A COG:S; EggNog:ENOG410PNGZ; InterPro:IPR001279,IPR036866; PFAM:PF00753 AKAW2_20953A COG:S; EggNog:ENOG410PJ7B AKAW2_20955A COG:A; EggNog:ENOG410PH4U; InterPro:IPR027417,IPR001650,IPR014014,IPR014001, IPR011545,IPR000629; PFAM:PF00270,PF00271; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0004386 - helicase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA] AKAW2_20956S COG:B,K; EggNog:ENOG410PFFE; InterPro:IPR017328,IPR026590,IPR026591,IPR029035, IPR003000; PFAM:PF02146; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_function: GO:0017136 - NAD-dependent histone deacetylase activity [Evidence IEA]; go_function: GO:0070403 - NAD+ binding [Evidence IEA] AKAW2_20957S COG:U; EggNog:ENOG410PHBS; InterPro:IPR032800,IPR010308,IPR040241; PFAM:PF06011,PF14558; SECRETED:SignalP(1-22); TransMembrane:7 (n3-14c22/23o332-358i386-406o412-434i475-495o501-524i531- 550o570-592i) AKAW2_20958A COG:A; EggNog:ENOG410Q13V; InterPro:IPR036236,IPR000690,IPR003604,IPR017340, IPR013085; PFAM:PF06220; go_component: GO:0005634 - nucleus [Evidence IEA]; go_component: GO:0005685 - U1 snRNP [Evidence IEA]; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0000387 - spliceosomal snRNP assembly [Evidence IEA]; go_process: GO:0000398 - mRNA splicing, via spliceosome [Evidence IEA] AKAW2_20959A COG:S; EggNog:ENOG410PXXD AKAW2_20960A antiSMASH:Cluster_2.4 AKAW2_20961S COG:S; EggNog:ENOG410PRUK; InterPro:IPR022024; PFAM:PF12223; antiSMASH:Cluster_2.4 AKAW2_20962A COG:Z; EggNog:ENOG410PHDF; InterPro:IPR020902,IPR004000,IPR043129; PFAM:PF00022; antiSMASH:Cluster_2.4 AKAW2_20963A BUSCO:EOG092658CI; COG:G; EggNog:ENOG410PRX7; InterPro:IPR039042,IPR007235; antiSMASH:Cluster_2.4; go_function: GO:0016758 - transferase activity, transferring hexosyl groups [Evidence IEA]; go_process: GO:0006488 - dolichol-linked oligosaccharide biosynthetic process [Evidence IEA] AKAW2_20964S BUSCO:EOG09264KIV; COG:J; EggNog:ENOG410PH1C; InterPro:IPR039848,IPR019349; PFAM:PF10213; antiSMASH:Cluster_2.4; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_process: GO:0032543 - mitochondrial translation [Evidence IEA] AKAW2_20965A COG:S; EggNog:ENOG410PTIC; InterPro:IPR000571; antiSMASH:Cluster_2.4; go_function: GO:0046872 - metal ion binding [Evidence IEA] AKAW2_20966A COG:Q; EggNog:ENOG410PVKZ; InterPro:IPR001128,IPR002403,IPR036396; PFAM:PF00067; SMCOG1034:cytochrome P450; TransMembrane:2 (o30-50i335-357o); antiSMASH:Cluster_2.4; go_function: GO:0004497 - monooxygenase activity [Evidence IEA]; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_20967A InterPro:IPR027443; antiSMASH:Cluster_2.4 AKAW2_20968A COG:I; EggNog:ENOG410PH4X; InterPro:IPR000873,IPR020845,IPR009081,IPR006162, IPR036736,IPR010071,IPR042099,IPR023213,IPR001242; PFAM:PF00501,PF00668,PF00550; SMCOG1002:AMP-dependent synthetase and ligase; TransMembrane:1 (o37-59i); antiSMASH:Cluster_2.4; go_function: GO:0003824 - catalytic activity [Evidence IEA] AKAW2_20969S SECRETED:SignalP(1-28); antiSMASH:Cluster_2.4 AKAW2_20970A COG:O; EggNog:ENOG410PVDJ; InterPro:IPR017795; MEROPS:MER0126985; antiSMASH:Cluster_2.4; go_function: GO:0016765 - transferase activity, transferring alkyl or aryl (other than methyl) groups [Evidence IEA]; go_process: GO:0009820 - alkaloid metabolic process [Evidence IEA] AKAW2_20971A COG:B; EggNog:ENOG410QDWM; InterPro:IPR041684,IPR019786,IPR040934,IPR000953, IPR000330,IPR038718,IPR001650,IPR011011,IPR014001, IPR027417,IPR001965,IPR016197,IPR013083; PFAM:PF00176,PF11496,PF15446,PF00271,PF18585; antiSMASH:Cluster_2.4; go_function: GO:0005524 - ATP binding [Evidence IEA] AKAW2_20973S COG:A; EggNog:ENOG410PP14; InterPro:IPR029028,IPR029026,IPR029064,IPR001537, IPR013123; PFAM:PF08032,PF00588; antiSMASH:Cluster_2.4; go_function: GO:0003723 - RNA binding [Evidence IEA]; go_function: GO:0008168 - methyltransferase activity [Evidence IEA]; go_function: GO:0008173 - RNA methyltransferase activity [Evidence IEA]; go_process: GO:0006396 - RNA processing [Evidence IEA] AKAW2_20972A COG:K; EggNog:ENOG410PG55; InterPro:IPR036306,IPR027417,IPR017884,IPR000330, IPR038718,IPR009057,IPR001650,IPR001005,IPR014001, IPR015194,IPR015195; PFAM:PF09110,PF00176,PF09111,PF00271,PF04851; antiSMASH:Cluster_2.4; go_component: GO:0005634 - nucleus [Evidence IEA]; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016818 - hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [Evidence IEA]; go_function: GO:0031491 - nucleosome binding [Evidence IEA]; go_process: GO:0006338 - chromatin remodeling [Evidence IEA]; go_process: GO:0043044 - ATP-dependent chromatin remodeling [Evidence IEA] AKAW2_20974S COG:S; EggNog:ENOG410PQR1; InterPro:IPR029196; PFAM:PF15251; antiSMASH:Cluster_2.4 AKAW2_20975A COG:S; EggNog:ENOG410PT20; InterPro:IPR028036; PFAM:PF15055; TransMembrane:1 (i77-95o); antiSMASH:Cluster_2.4 AKAW2_20976S COG:U; EggNog:ENOG410PIT0; InterPro:IPR011012,IPR028565,IPR036168,IPR018240; PFAM:PF00928; go_component: GO:0030131 - clathrin adaptor complex [Evidence IEA]; go_process: GO:0006886 - intracellular protein transport [Evidence IEA]; go_process: GO:0016192 - vesicle-mediated transport [Evidence IEA] AKAW2_20977A COG:G; EggNog:ENOG410PMG2; InterPro:IPR008922,IPR002227; PFAM:PF00264; SECRETED:SignalP(1-18); go_function: GO:0016491 - oxidoreductase activity [Evidence IEA] AKAW2_20978S COG:S; EggNog:ENOG410PWYB; TransMembrane:7 (o20-42i54-72o103-123i130-152o195-215i227-246o266-286i) AKAW2_20979S COG:T; EggNog:ENOG410PKCJ; InterPro:IPR000719,IPR011009,IPR017441; PFAM:PF00069; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_20980A COG:C; EggNog:ENOG410PGT9; InterPro:IPR015590,IPR012394,IPR016161,IPR016162, IPR016163; PFAM:PF00171; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0016620 - oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Evidence IEA]; go_process: GO:0006081 - cellular aldehyde metabolic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_20981A COG:C; EggNog:ENOG410PGND; InterPro:IPR006254,IPR040442,IPR015813,IPR018523; PFAM:PF00463,PF13714; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0004451 - isocitrate lyase activity [Evidence IEA]; go_process: GO:0019752 - carboxylic acid metabolic process [Evidence IEA] AKAW2_20983A BUSCO:EOG09260TWS; CAZy:GH37; COG:G; EggNog:ENOG410PFDB; InterPro:IPR018232,IPR011120,IPR008928,IPR001661, IPR012341; PFAM:PF07492,PF01204; go_component: GO:0005737 - cytoplasm [Evidence IEA]; go_function: GO:0004555 - alpha,alpha-trehalase activity [Evidence IEA]; go_function: GO:0005509 - calcium ion binding [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA]; go_process: GO:0005991 - trehalose metabolic process [Evidence IEA]; go_process: GO:0005993 - trehalose catabolic process [Evidence IEA] AKAW2_20984A COG:P; EggNog:ENOG410PJTG; InterPro:IPR003445,IPR015958,IPR004773; PFAM:PF02386; TransMembrane:8 (i12-31o65-90i325-350o397-418i461-481o523-543i584-603o609- 632i); go_component: GO:0005887 - integral component of plasma membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0008324 - cation transmembrane transporter activity [Evidence IEA]; go_function: GO:0015079 - potassium ion transmembrane transporter activity [Evidence IEA]; go_process: GO:0006812 - cation transport [Evidence IEA]; go_process: GO:0030007 - cellular potassium ion homeostasis [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA]; go_process: GO:0071805 - potassium ion transmembrane transport [Evidence IEA] AKAW2_20985A COG:Q; EggNog:ENOG410PJCA; InterPro:IPR002347,IPR036291,IPR020904; PFAM:PF00106,PF13561,PF08659; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_20986S BUSCO:EOG09264IPL; COG:O,T; EggNog:ENOG410PK8T; InterPro:IPR003323,IPR038765; MEROPS:MER0400048; PFAM:PF02338 AKAW2_20987A COG:S; EggNog:ENOG410PWPY; InterPro:IPR029063,IPR008854; PFAM:PF08241,PF05724; go_function: GO:0008757 - S-adenosylmethionine-dependent methyltransferase activity [Evidence IEA] AKAW2_20988S COG:G; EggNog:ENOG410PG9Q; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i107-131o143-163i175-202o208-225i237-259o265-283i347- 365o377-402i437-454o460-483i504-521o527-547i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_20989S COG:S; EggNog:ENOG410Q1R0; TransMembrane:1 (o1058-1077i) AKAW2_20990A COG:E; EggNog:ENOG410PIB1; InterPro:IPR043137,IPR029055,IPR043138; MEROPS:MER0094876; PFAM:PF01019 AKAW2_20991S COG:S; EggNog:ENOG410PNG1; InterPro:IPR011011 AKAW2_20992A COG:S; EggNog:ENOG410PPW6 AKAW2_20993A COG:S; EggNog:ENOG410PWN7; InterPro:IPR012349,IPR002563; PFAM:PF01613; go_function: GO:0010181 - FMN binding [Evidence IEA] AKAW2_20994A COG:G,O; EggNog:ENOG410PTCF; InterPro:IPR002889; PFAM:PF01822; SECRETED:SignalP(1-30); TransMembrane:1 (n13-25c30/31o194-218i) AKAW2_20995A COG:I; EggNog:ENOG410PKTK; InterPro:IPR000462,IPR043130,IPR004533; PFAM:PF01066; TransMembrane:3 (o20-36i57-76o82-106i); go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0016780 - phosphotransferase activity, for other substituted phosphate groups [Evidence IEA]; go_process: GO:0008654 - phospholipid biosynthetic process [Evidence IEA] AKAW2_20996A COG:J; EggNog:ENOG410PPNM; InterPro:IPR007504,IPR009000,IPR038664; PFAM:PF04410; go_process: GO:0001522 - pseudouridine synthesis [Evidence IEA]; go_process: GO:0042254 - ribosome biogenesis [Evidence IEA] AKAW2_20997S COG:J; EggNog:ENOG410PFEM; InterPro:IPR036621,IPR006195,IPR002320,IPR012675, IPR012676,IPR004154,IPR033728,IPR018163,IPR012947, IPR002314,IPR004095; PFAM:PF03129,PF00587,PF07973; go_component: GO:0005737 - cytoplasm [Evidence IEA]; go_function: GO:0000166 - nucleotide binding [Evidence IEA]; go_function: GO:0004812 - aminoacyl-tRNA ligase activity [Evidence IEA]; go_function: GO:0004829 - threonine-tRNA ligase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006418 - tRNA aminoacylation for protein translation [Evidence IEA]; go_process: GO:0006435 - threonyl-tRNA aminoacylation [Evidence IEA]; go_process: GO:0043039 - tRNA aminoacylation [Evidence IEA] AKAW2_20998S COG:G; EggNog:ENOG410PSVX; InterPro:IPR006740 AKAW2_20999S TransMembrane:2 (i38-58o64-86i) AKAW2_21000S COG:T; EggNog:ENOG410PFQD; InterPro:IPR017441,IPR008271,IPR003527,IPR000719, IPR011009; PFAM:PF07714,PF00069; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0004707 - MAP kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_21001A COG:S; EggNog:ENOG410PW3F; InterPro:IPR036864,IPR001138; PFAM:PF00172; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_21002S COG:Q; EggNog:ENOG410PW49; InterPro:IPR036291,IPR002347; PFAM:PF08659,PF00106,PF13561; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_21003S COG:O; EggNog:ENOG410PM7I; InterPro:IPR023753,IPR036188; PFAM:PF07992,PF00070; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_21004A COG:I; EggNog:ENOG410PFDA; InterPro:IPR003819; PFAM:PF02668; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_21005S COG:G; EggNog:ENOG410QDIK; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i67-86o116-134i141-160o172-191i203-223o235-256i316- 338o350-368i380-400o406-429i441-461o467-489i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_21006A COG:K; EggNog:ENOG410PMFV; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_21007S COG:C; EggNog:ENOG410PGU6; InterPro:IPR023210,IPR036812,IPR005399; PFAM:PF00248 AKAW2_21008A TransMembrane:1 (o218-235i) AKAW2_21010S COG:J; EggNog:ENOG410PPG4; InterPro:IPR036249,IPR040079,IPR036282,IPR010987, IPR004045,IPR004046; PFAM:PF00043,PF14497,PF13417,PF13410,PF02798; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0006749 - glutathione metabolic process [Evidence IEA] AKAW2_21009A CAZy:AA3; COG:E; EggNog:ENOG410PH8X; InterPro:IPR036188,IPR012400,IPR000172,IPR007867; PFAM:PF00732,PF05199; go_function: GO:0016614 - oxidoreductase activity, acting on CH-OH group of donors [Evidence IEA]; go_function: GO:0046577 - long-chain-alcohol oxidase activity [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_21011S COG:S; EggNog:ENOG410PGFP; InterPro:IPR003131,IPR011333; PFAM:PF02214; go_process: GO:0051260 - protein homooligomerization [Evidence IEA] AKAW2_21012A COG:D; EggNog:ENOG410PGKU; InterPro:IPR023267,IPR001678,IPR029063; PFAM:PF01189; go_function: GO:0008168 - methyltransferase activity [Evidence IEA]; go_process: GO:0001510 - RNA methylation [Evidence IEA] AKAW2_21013S COG:S; EggNog:ENOG410PTGX; InterPro:IPR016181,IPR039143,IPR000182; PFAM:PF13444,PF13508,PF13673,PF00583; go_function: GO:0004343 - glucosamine 6-phosphate N-acetyltransferase activity [Evidence IEA]; go_function: GO:0008080 - N-acetyltransferase activity [Evidence IEA]; go_process: GO:0006048 - UDP-N-acetylglucosamine biosynthetic process [Evidence IEA] AKAW2_21014A COG:S; EggNog:ENOG410QECQ; InterPro:IPR011011,IPR017455,IPR000306,IPR013083; PFAM:PF01363; go_function: GO:0046872 - metal ion binding [Evidence IEA] AKAW2_21017S COG:E; EggNog:ENOG410PJE6; InterPro:IPR002293,IPR004840; PFAM:PF13520,PF00324; TransMembrane:12 (i47-73o79-99i111-130o136-160i172-193o199-218i285-306o336- 356i387-406o412-434i454-477o483-504i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0006865 - amino acid transport [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_21018A COG:T; EggNog:ENOG410PWEM; InterPro:IPR000719,IPR011009,IPR008271; PFAM:PF00069; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_21019A COG:C; EggNog:ENOG410QDYN; InterPro:IPR006140,IPR036291,IPR006139,IPR029753; PFAM:PF00389,PF02826; go_function: GO:0016616 - oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Evidence IEA]; go_function: GO:0051287 - NAD binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_21020S COG:I; EggNog:ENOG410PK9C; InterPro:IPR005804; PFAM:PF00487; TransMembrane:4 (i105-125o131-151i221-241o261-284i); go_process: GO:0006629 - lipid metabolic process [Evidence IEA] AKAW2_21021A CAZy:GT4; COG:M; EggNog:ENOG410PHXG; InterPro:IPR001296,IPR028098; PFAM:PF00534,PF13524,PF13439,PF13579,PF13692; TransMembrane:1 (o447-467i) AKAW2_21022S COG:G; EggNog:ENOG410PJKA; InterPro:IPR028356,IPR028357,IPR036220,IPR036291, IPR001732,IPR014027,IPR014026,IPR017476,IPR008927; PFAM:PF00984,PF03720; go_function: GO:0003979 - UDP-glucose 6-dehydrogenase activity [Evidence IEA]; go_function: GO:0016616 - oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Evidence IEA]; go_function: GO:0051287 - NAD binding [Evidence IEA]; go_process: GO:0000271 - polysaccharide biosynthetic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_21023A COG:O; EggNog:ENOG410PNF8; InterPro:IPR036249,IPR040079,IPR036282,IPR010987, IPR004045,IPR004046; PFAM:PF13409,PF00043,PF14497,PF13417,PF13410, PF02798; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0006749 - glutathione metabolic process [Evidence IEA] AKAW2_21024S COG:S; EggNog:ENOG410PSAF; InterPro:IPR009866; TransMembrane:1 (o35-54i); go_component: GO:0005739 - mitochondrion [Evidence IEA]; go_function: GO:0008137 - NADH dehydrogenase (ubiquinone) activity [Evidence IEA] AKAW2_21025A COG:A; EggNog:ENOG410PQVW; InterPro:IPR010516; PFAM:PF06487 AKAW2_21026S BUSCO:EOG0926420U; COG:A; EggNog:ENOG410PK4K; InterPro:IPR014906,IPR036285,IPR004098,IPR039979; PFAM:PF02840,PF08799; go_component: GO:0005681 - spliceosomal complex [Evidence IEA]; go_process: GO:0008380 - RNA splicing [Evidence IEA] AKAW2_21027S COG:T; EggNog:ENOG410PUV8; InterPro:IPR000719,IPR011009,IPR008271; PFAM:PF00069; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_21028A COG:T; EggNog:ENOG410PKH4; InterPro:IPR029729,IPR036188,IPR029731 AKAW2_21029S COG:U; EggNog:ENOG410PJ7U; InterPro:IPR027417,IPR006689; PFAM:PF08477,PF01926,PF00025; go_function: GO:0005525 - GTP binding [Evidence IEA] AKAW2_21030S COG:S; EggNog:ENOG410PXJQ AKAW2_21031A BUSCO:EOG09262TO9; CAZy:GT4; COG:M; EggNog:ENOG410PG2V; InterPro:IPR001296,IPR013234; PFAM:PF00534,PF13439,PF08288,PF13579,PF13692; TransMembrane:1 (o420-439i); go_process: GO:0006506 - GPI anchor biosynthetic process [Evidence IEA] AKAW2_21032S BUSCO:EOG09261EM7; COG:A; EggNog:ENOG410PIR2; InterPro:IPR027417,IPR001650,IPR014014,IPR014001, IPR011545,IPR000629; PFAM:PF04851,PF00270,PF00271; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0004386 - helicase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA] AKAW2_21033A COG:S; EggNog:ENOG410Q0A5; InterPro:IPR036148,IPR012705,IPR042188,IPR005656, IPR042183; PFAM:PF03972; go_function: GO:0016829 - lyase activity [Evidence IEA]; go_function: GO:0047547 - 2-methylcitrate dehydratase activity [Evidence IEA]; go_function: GO:0051537 - 2 iron, 2 sulfur cluster binding [Evidence IEA]; go_process: GO:0019679 - propionate metabolic process, methylcitrate cycle [Evidence IEA] AKAW2_21034S COG:C; EggNog:ENOG410PIVH; InterPro:IPR019810,IPR002020,IPR036969,IPR016142, IPR016143; PFAM:PF00285; go_function: GO:0046912 - transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer [Evidence IEA] AKAW2_21035S SECRETED:SignalP(1-20) AKAW2_21036S COG:S; EggNog:ENOG410Q1JU AKAW2_21037A InterPro:IPR029463,IPR024079; SECRETED:SignalP(1-27); go_function: GO:0004222 - metalloendopeptidase activity [Evidence IEA]; go_function: GO:0008237 - metallopeptidase activity [Evidence IEA] AKAW2_21038S CAZy:GH18; COG:G; EggNog:ENOG410PI86; InterPro:IPR036861,IPR011583,IPR029070,IPR001223, IPR007110,IPR017853,IPR018371,IPR018392,IPR001002, IPR001579,IPR036779; PFAM:PF00187,PF00704; SECRETED:SignalP(1-21); go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_function: GO:0008061 - chitin binding [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_21039S COG:S; EggNog:ENOG410PWCM; InterPro:IPR042183,IPR036148,IPR005656; PFAM:PF03972; go_function: GO:0016829 - lyase activity [Evidence IEA] AKAW2_21040S CAZy:GH3; COG:G; EggNog:ENOG410PMRH; InterPro:IPR017853,IPR036962,IPR002772,IPR036881, IPR001764,IPR013783,IPR026891; PFAM:PF14310,PF00933,PF01915; go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_21041A COG:S; EggNog:ENOG410PPCG AKAW2_21042S COG:S; EggNog:ENOG410PU55; InterPro:IPR009413; PFAM:PF06355; go_process: GO:0019836 - hemolysis by symbiont of host erythrocytes [Evidence IEA] AKAW2_21043A COG:Q; EggNog:ENOG410PHP4; InterPro:IPR017871,IPR027417,IPR003593,IPR011527, IPR003439,IPR036640; PFAM:PF00005,PF00664; TransMembrane:14 (n4-15c19/20o54-75i95-118o130-148i160-182o188-206i306- 324o336-357i438-457o463-481i542-568o574-596i913-940o960- 984i1048-1076o); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA]; go_function: GO:0042626 - ATPase-coupled transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_21044S COG:E; EggNog:ENOG410PI7P; InterPro:IPR000277,IPR015424,IPR015421,IPR015422; PFAM:PF01053; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0030170 - pyridoxal phosphate binding [Evidence IEA]; go_process: GO:0019346 - transsulfuration [Evidence IEA] AKAW2_21045S COG:S; EggNog:ENOG410PT6A AKAW2_21046A BUSCO:EOG09262V3O; COG:I; EggNog:ENOG410PFBV; InterPro:IPR006694; PFAM:PF04116; TransMembrane:3 (o33-53i128-144o194-219i); go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0008610 - lipid biosynthetic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_21047S BUSCO:EOG09264U81; COG:D,Z; EggNog:ENOG410PWYN; InterPro:IPR011323,IPR034737,IPR011057,IPR018103, IPR018105; PFAM:PF00838 AKAW2_21048A COG:S; EggNog:ENOG410PNCW; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_21049A BUSCO:EOG092647CM; COG:U; EggNog:ENOG410PNRP; InterPro:IPR002778,IPR022938,IPR036521; PFAM:PF01922; go_component: GO:0048500 - signal recognition particle [Evidence IEA]; go_function: GO:0008312 - 7S RNA binding [Evidence IEA]; go_process: GO:0006614 - SRP-dependent cotranslational protein targeting to membrane [Evidence IEA] AKAW2_21050S COG:E; EggNog:ENOG410QDUU; InterPro:IPR005814,IPR015424,IPR015421,IPR015422; PFAM:PF00202; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0008483 - transaminase activity [Evidence IEA]; go_function: GO:0030170 - pyridoxal phosphate binding [Evidence IEA] AKAW2_21053A BUSCO:EOG09260RRC; COG:A; EggNog:ENOG410PIVA; InterPro:IPR036866,IPR011108,IPR001279,IPR022712, IPR021718; PFAM:PF11718,PF07521,PF10996,PF16661,PF00753; TransMembrane:1 (i173-193o) AKAW2_21055S COG:S; EggNog:ENOG410PHE4; InterPro:IPR007900; PFAM:PF05236; go_component: GO:0005669 - transcription factor TFIID complex [Evidence IEA]; go_process: GO:0006352 - DNA-templated transcription, initiation [Evidence IEA] AKAW2_21056S COG:T; EggNog:ENOG410PFTM; InterPro:IPR017441,IPR008271,IPR000719,IPR011009; PFAM:PF07714,PF00069; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_21057A COG:U; EggNog:ENOG410PFBD; InterPro:IPR004686; PFAM:PF03820; TransMembrane:3 (i149-167o179-200i286-306o); go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0015075 - ion transmembrane transporter activity [Evidence IEA]; go_process: GO:0006811 - ion transport [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_21058A COG:S; EggNog:ENOG410PQXW; InterPro:IPR019787,IPR019786,IPR011011,IPR001965, IPR013083; PFAM:PF00628 AKAW2_21059S COG:S; EggNog:ENOG410PQXY; InterPro:IPR018744; PFAM:PF10056 AKAW2_21061S BUSCO:EOG09261EY9; COG:S; EggNog:ENOG410PFCW; InterPro:IPR001656,IPR020103,IPR042214,IPR011760; PFAM:PF01142; go_function: GO:0003723 - RNA binding [Evidence IEA]; go_function: GO:0009982 - pseudouridine synthase activity [Evidence IEA]; go_process: GO:0001522 - pseudouridine synthesis [Evidence IEA]; go_process: GO:0009451 - RNA modification [Evidence IEA] AKAW2_21062S COG:S; EggNog:ENOG410PNHD; InterPro:IPR011009 AKAW2_21063A COG:S; EggNog:ENOG410PNQK AKAW2_21064S COG:S; EggNog:ENOG410Q1JZ; TransMembrane:1 (o98-120i) AKAW2_21065S COG:I; EggNog:ENOG410PIKZ; InterPro:IPR002076; PFAM:PF01151; TransMembrane:7 (o63-81i102-126o196-218i230-253o259-277i289-310o384-405i); go_component: GO:0016021 - integral component of membrane [Evidence IEA] AKAW2_21066S CAZy:GH35; COG:G; EggNog:ENOG410PGRS; InterPro:IPR025300,IPR025972,IPR037110,IPR008979, IPR036833,IPR018954,IPR017853,IPR001944,IPR031330; PFAM:PF13363,PF10435,PF00150,PF01301,PF13364; SECRETED:SignalP(1-20); go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_21067A COG:G; EggNog:ENOG410PHFT; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i63-80o108-126i133-154o160-183i195-215o227-250i303- 322o334-356i368-389o395-413i425-446o458-479i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_21068A COG:S; EggNog:ENOG410PGSG AKAW2_21070S COG:S; EggNog:ENOG410PMYP; TransMembrane:1 (o31-51i) AKAW2_21071S COG:S; EggNog:ENOG410Q2BH AKAW2_21072S COG:S; EggNog:ENOG410PMJI; InterPro:IPR021950; PFAM:PF12090; go_component: GO:0000124 - SAGA complex [Evidence IEA]; go_function: GO:0003712 - transcription coregulator activity [Evidence IEA] AKAW2_21073A COG:S; EggNog:ENOG410PPXQ; InterPro:IPR006861,IPR019084,IPR039764; PFAM:PF09598; go_function: GO:0003723 - RNA binding [Evidence IEA] AKAW2_21074A COG:K; EggNog:ENOG410PKR7; InterPro:IPR004827; go_function: GO:0003700 - DNA-binding transcription factor activity [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_21075S BUSCO:EOG092635SS; COG:U; EggNog:ENOG410PF9X; InterPro:IPR038322,IPR006708; PFAM:PF04614; go_component: GO:0005777 - peroxisome [Evidence IEA] AKAW2_21077A COG:S; EggNog:ENOG410PZI7 AKAW2_21078A COG:S; EggNog:ENOG410Q0VF; SECRETED:SignalP(1-21); TransMembrane:1 (n8-20c38/39o193-215i) AKAW2_21079A COG:S; EggNog:ENOG410Q0K9; InterPro:IPR020301; PFAM:PF10906 AKAW2_21080S COG:T; EggNog:ENOG410PH7I; InterPro:IPR029021,IPR003595,IPR016130,IPR000242, IPR000387; PFAM:PF00102; go_function: GO:0004725 - protein tyrosine phosphatase activity [Evidence IEA]; go_function: GO:0016791 - phosphatase activity [Evidence IEA]; go_process: GO:0006470 - protein dephosphorylation [Evidence IEA]; go_process: GO:0016311 - dephosphorylation [Evidence IEA] AKAW2_21081A COG:S; EggNog:ENOG410PNRV; InterPro:IPR006976; PFAM:PF04892; TransMembrane:3 (n7-14c18/19o42-59i66-85o97-117i) AKAW2_21082S BUSCO:EOG09261476; COG:K; EggNog:ENOG410PG6A; InterPro:IPR037782,IPR036427,IPR009072,IPR018359, IPR006565,IPR001487; PFAM:PF00439,PF07524; go_component: GO:0000124 - SAGA complex [Evidence IEA]; go_component: GO:0046695 - SLIK (SAGA-like) complex [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_function: GO:0046982 - protein heterodimerization activity [Evidence IEA] AKAW2_21083A COG:J; EggNog:ENOG410PISF; InterPro:IPR012337,IPR032474,IPR036397,IPR032472, IPR032473,IPR036085,IPR003100,IPR003165,IPR014811; PFAM:PF16487,PF02171,PF16486,PF02170,PF08699, PF16488; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_21084A COG:P; EggNog:ENOG410PFMV; InterPro:IPR003020,IPR011531; TransMembrane:11 (o137-155i167-193o213-233i240-260o280-300i312-332o363- 384i405-427o488-512i544-564o570-591i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0005452 - inorganic anion exchanger activity [Evidence IEA]; go_process: GO:0006820 - anion transport [Evidence IEA] AKAW2_21085A BUSCO:EOG09263MEM; COG:A; EggNog:ENOG410PFVG; InterPro:IPR036612,IPR031150,IPR001878,IPR004087, IPR032570,IPR036875,IPR004088; PFAM:PF16275,PF00013,PF00098; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0003723 - RNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_function: GO:0045131 - pre-mRNA branch point binding [Evidence IEA]; go_process: GO:0000398 - mRNA splicing, via spliceosome [Evidence IEA] AKAW2_21086A COG:O; EggNog:ENOG410Q1CZ; InterPro:IPR036249,IPR040079,IPR036282,IPR010987, IPR004045,IPR004046; PFAM:PF13409,PF00043,PF14497,PF13417,PF13410, PF02798; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0006749 - glutathione metabolic process [Evidence IEA] AKAW2_21087A COG:P,Q; EggNog:ENOG410PFX0; InterPro:IPR017938,IPR017927,IPR013130,IPR013121, IPR039261,IPR013112; PFAM:PF01794,PF08030; SECRETED:SignalP(1-16); TransMembrane:7 (n4-11c16/17o40-58i124-146o158-176i197-215o235-253i265- 284o290-313i); go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_21088A TransMembrane:3 (o40-63i75-91o97-120i) AKAW2_21089A BUSCO:EOG09261OXV; COG:S; EggNog:ENOG410PG8Z; InterPro:IPR011990,IPR019734,IPR027523,IPR028275, IPR025697,IPR033646; PFAM:PF13374,PF13236,PF12807,PF13424,PF15044; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0048312 - intracellular distribution of mitochondria [Evidence IEA] AKAW2_21090S COG:P; EggNog:ENOG410PMVB; InterPro:IPR006153; PFAM:PF00999; TransMembrane:11 (o12-32i39-59o65-84i96-117o129-150i162-184o204-223i244- 272o320-341i348-368o440-463i); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0015299 - solute:proton antiporter activity [Evidence IEA]; go_process: GO:0006812 - cation transport [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_21092A COG:S; EggNog:ENOG410Q269 AKAW2_21093A COG:S; EggNog:ENOG410PFK3; InterPro:IPR011990,IPR027417,IPR042621,IPR031350; PFAM:PF17109; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_21095A COG:S; EggNog:ENOG410PVCK; InterPro:IPR010730; PFAM:PF06985 AKAW2_21096S COG:S; EggNog:ENOG410PJ14; InterPro:IPR027417,IPR041664; PFAM:PF13191 AKAW2_21097S COG:S; EggNog:ENOG410PWBX; TransMembrane:8 (i42-65o77-98i105-126o132-149i177-196o216-238i293-313o325- 345i) AKAW2_21098A COG:S; EggNog:ENOG410PJXJ; InterPro:IPR007568; PFAM:PF04479; TransMembrane:7 (o33-52i64-82o94-118i138-158o178-199i211-235o255-279i); go_component: GO:0016021 - integral component of membrane [Evidence IEA] AKAW2_21099A COG:G; EggNog:ENOG410PJJB; InterPro:IPR018970,IPR019789,IPR029061,IPR018969, IPR019790,IPR005593,IPR009014; PFAM:PF09364,PF03894,PF09363; TransMembrane:1 (n3-13c21/22o584-604i); go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0016832 - aldehyde-lyase activity [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_21100S COG:C; EggNog:ENOG410PJTT; InterPro:IPR004372,IPR023865,IPR043129,IPR000890; PFAM:PF00871; go_function: GO:0016301 - kinase activity [Evidence IEA]; go_function: GO:0016774 - phosphotransferase activity, carboxyl group as acceptor [Evidence IEA]; go_process: GO:0006082 - organic acid metabolic process [Evidence IEA]; go_process: GO:0016310 - phosphorylation [Evidence IEA] AKAW2_21101S COG:U; EggNog:ENOG410PFKA; InterPro:IPR005225,IPR001806,IPR027417; PFAM:PF04670,PF00025,PF08477,PF00071,PF01926; go_function: GO:0003924 - GTPase activity [Evidence IEA]; go_function: GO:0005525 - GTP binding [Evidence IEA] AKAW2_21102S COG:J; EggNog:ENOG410PJ7T; InterPro:IPR000554; PFAM:PF01251; go_component: GO:0005840 - ribosome [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_process: GO:0006412 - translation [Evidence IEA] AKAW2_21103A COG:N; EggNog:ENOG410PH51; InterPro:IPR008603; PFAM:PF05502; go_component: GO:0005869 - dynactin complex [Evidence IEA] AKAW2_21104S COG:Q; EggNog:ENOG410PJCF; InterPro:IPR013216,IPR029063; PFAM:PF13489,PF13649,PF08241; go_function: GO:0008168 - methyltransferase activity [Evidence IEA] AKAW2_21105A BUSCO:EOG09264V51; COG:Z; EggNog:ENOG410PQEJ; InterPro:IPR006789,IPR036743; PFAM:PF04699; go_component: GO:0005885 - Arp2/3 protein complex [Evidence IEA]; go_component: GO:0015629 - actin cytoskeleton [Evidence IEA]; go_process: GO:0030833 - regulation of actin filament polymerization [Evidence IEA]; go_process: GO:0034314 - Arp2/3 complex-mediated actin nucleation [Evidence IEA] AKAW2_21106A COG:P; EggNog:ENOG410PGJZ; InterPro:IPR006068,IPR018303,IPR023298,IPR023299, IPR001757,IPR006408,IPR004014,IPR036412,IPR008250, IPR023214; PFAM:PF00689,PF13246,PF00122,PF00702; TransMembrane:10 (i246-263o275-294i445-466o486-513i926-947o959-976i996- 1019o1039-1055i1076-1096o1108-1127i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0000166 - nucleotide binding [Evidence IEA]; go_function: GO:0005388 - calcium transmembrane transporter activity, phosphorylative mechanism [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0070588 - calcium ion transmembrane transport [Evidence IEA] AKAW2_21107A COG:S; EggNog:ENOG410PGSR; InterPro:IPR025700,IPR036188; PFAM:PF13434 AKAW2_21108A COG:S; EggNog:ENOG410PIUA AKAW2_21109A COG:I; EggNog:ENOG410PG2N; InterPro:IPR013746,IPR000590,IPR016039,IPR013528, IPR010122; PFAM:PF01154,PF08540; go_function: GO:0004421 - hydroxymethylglutaryl-CoA synthase activity [Evidence IEA]; go_function: GO:0016746 - transferase activity, transferring acyl groups [Evidence IEA]; go_process: GO:0006084 - acetyl-CoA metabolic process [Evidence IEA]; go_process: GO:0008299 - isoprenoid biosynthetic process [Evidence IEA]; go_process: GO:0010142 - farnesyl diphosphate biosynthetic process, mevalonate pathway [Evidence IEA] AKAW2_21110S COG:O,P; EggNog:ENOG410PI29; InterPro:IPR036757,IPR007365,IPR003137,IPR039373, IPR007484; MEROPS:MER0015691; PFAM:PF04253,PF02225,PF04389; TransMembrane:1 (i169-187o) AKAW2_21111A COG:S; EggNog:ENOG410PITE; InterPro:IPR013887; PFAM:PF08578 AKAW2_21112A COG:C; EggNog:ENOG410PQN5; InterPro:IPR019711; PFAM:PF10775; go_component: GO:0000276 - mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) [Evidence IEA]; go_process: GO:0015986 - ATP synthesis coupled proton transport [Evidence IEA] AKAW2_21113S BUSCO:EOG09262PAY; COG:K; EggNog:ENOG410PIN2; InterPro:IPR013150,IPR036915,IPR023486,IPR000812, IPR013137,IPR013763; PFAM:PF00382,PF08271; go_function: GO:0017025 - TBP-class protein binding [Evidence IEA]; go_process: GO:0006352 - DNA-templated transcription, initiation [Evidence IEA]; go_process: GO:0070897 - transcription preinitiation complex assembly [Evidence IEA] AKAW2_21114A COG:S; EggNog:ENOG410PJKN; InterPro:IPR021582; PFAM:PF11489 AKAW2_21115A COG:K; EggNog:ENOG410Q1CV; InterPro:IPR007219; PFAM:PF04082; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA] AKAW2_21116S COG:E; EggNog:ENOG410PF7Z; InterPro:IPR036038,IPR018300,IPR001544,IPR043131, IPR043132,IPR033939,IPR005786; PFAM:PF01063; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0004084 - branched-chain-amino-acid transaminase activity [Evidence IEA]; go_process: GO:0009081 - branched-chain amino acid metabolic process [Evidence IEA] AKAW2_21117A COG:A; EggNog:ENOG410PPQ9; InterPro:IPR033648,IPR038514,IPR007946,IPR033647; PFAM:PF05282 AKAW2_21118A COG:J; EggNog:ENOG410PP1Z; InterPro:IPR036967,IPR001971,IPR018102; PFAM:PF00411; go_component: GO:0005840 - ribosome [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_process: GO:0006412 - translation [Evidence IEA] AKAW2_21119S COG:E; EggNog:ENOG410PGS8; InterPro:IPR036291,IPR008927,IPR012385,IPR003099; PFAM:PF02153; go_function: GO:0004665 - prephenate dehydrogenase (NADP+) activity [Evidence IEA]; go_function: GO:0008977 - prephenate dehydrogenase (NAD+) activity [Evidence IEA]; go_process: GO:0006571 - tyrosine biosynthetic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_21120S COG:S; EggNog:ENOG410PN1X; InterPro:IPR038697,IPR005018,IPR015920,IPR006593; PFAM:PF16010,PF03188; SECRETED:SignalP(1-22); TransMembrane:5 (n6-17c22/23o222-246i258-278o290-309i329-350o362-381i) AKAW2_21121S BUSCO:EOG09260FPA; COG:D; EggNog:ENOG410PI0P; InterPro:IPR016024,IPR028267,IPR028268,IPR029452, IPR029453,IPR029451,IPR036274,IPR011072; PFAM:PF14664,PF14663,PF02185,PF14666,PF14668; go_component: GO:0031932 - TORC2 complex [Evidence IEA]; go_process: GO:0007165 - signal transduction [Evidence IEA]; go_process: GO:0031929 - TOR signaling [Evidence IEA] AKAW2_21122S COG:O; EggNog:ENOG410PKXY; InterPro:IPR001841,IPR017907,IPR015947,IPR003111, IPR013083; PFAM:PF13923,PF13920,PF00097,PF13445,PF13639, PF02190 AKAW2_21124S COG:A; EggNog:ENOG410PJT8; InterPro:IPR035979,IPR012677,IPR039171; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0003723 - RNA binding [Evidence IEA] AKAW2_21125A COG:J; EggNog:ENOG410PMZE; InterPro:IPR000754,IPR020568,IPR014721,IPR020574; PFAM:PF00380; go_component: GO:0005840 - ribosome [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_process: GO:0006412 - translation [Evidence IEA] AKAW2_21126S BUSCO:EOG092654LJ; COG:J; EggNog:ENOG410PN44; InterPro:IPR005823,IPR005822,IPR036899; PFAM:PF00572; go_component: GO:0005840 - ribosome [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_process: GO:0006412 - translation [Evidence IEA] AKAW2_21127A COG:Q; EggNog:ENOG410PFP4; InterPro:IPR002042,IPR019842; PFAM:PF01014; go_function: GO:0004846 - urate oxidase activity [Evidence IEA]; go_process: GO:0006144 - purine nucleobase metabolic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_21128S COG:U; EggNog:ENOG410Q2EH; InterPro:IPR020846,IPR001958,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i21-44o64-86i98-119o125-143i155-179o185-203i273-293o299- 321i333-352o358-382i403-427o433-457i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_21129A COG:S; EggNog:ENOG410PTG0 AKAW2_21130A COG:K; EggNog:ENOG410PIKR; InterPro:IPR036236,IPR013087 AKAW2_21131A COG:S; EggNog:ENOG410Q2R9; TransMembrane:6 (n4-13c20/21o44-64i130-148o154-176i196-214o245-269i356- 374o) AKAW2_21132A COG:E; EggNog:ENOG410PFV8; InterPro:IPR002293; PFAM:PF00324,PF13520; TransMembrane:13 (i60-84o96-114i126-145o151-175i187-209o215-236i257- 277o297-320i349-378o398-419i426-449o464-485i497-518o); go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_21133A COG:S; EggNog:ENOG410PT39; InterPro:IPR019182; PFAM:PF09796; TransMembrane:1 (o43-62i) AKAW2_21134A COG:O; EggNog:ENOG410PJ6R; InterPro:IPR036249,IPR013766; TransMembrane:1 (o539-556i) AKAW2_21135S COG:C; EggNog:ENOG410PPI3; InterPro:IPR006806; PFAM:PF04716; go_process: GO:0022904 - respiratory electron transport chain [Evidence IEA] AKAW2_21136S COG:U; EggNog:ENOG410PFS1; InterPro:IPR036322,IPR015943,IPR001680,IPR016453, IPR006692,IPR020472,IPR017986; PFAM:PF00400,PF04053; go_component: GO:0030117 - membrane coat [Evidence IEA]; go_function: GO:0005198 - structural molecule activity [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0006886 - intracellular protein transport [Evidence IEA]; go_process: GO:0016192 - vesicle-mediated transport [Evidence IEA] AKAW2_21137A COG:T; EggNog:ENOG410Q6RP; InterPro:IPR017441,IPR008271,IPR000961,IPR000719, IPR011009; PFAM:PF07714,PF00069; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0004674 - protein serine/threonine kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_21138S COG:B; EggNog:ENOG410PFFS; InterPro:IPR041983,IPR017884,IPR043145,IPR016827, IPR009057,IPR007526,IPR001005,IPR000433; PFAM:PF00249,PF00569,PF04433; go_function: GO:0003713 - transcription coactivator activity [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006357 - regulation of transcription by RNA polymerase II [Evidence IEA]; go_process: GO:0035065 - regulation of histone acetylation [Evidence IEA] AKAW2_21139S COG:I; EggNog:ENOG410PH1Q; InterPro:IPR001753,IPR029045,IPR014748; PFAM:PF00378; go_function: GO:0003824 - catalytic activity [Evidence IEA] AKAW2_21140A COG:C; EggNog:ENOG410PKMJ; InterPro:IPR013118,IPR036291,IPR023028,IPR000669, IPR013131,IPR008927,IPR013328; PFAM:PF01232,PF08125; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0008926 - mannitol-1-phosphate 5-dehydrogenase activity [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0019594 - mannitol metabolic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_21141A COG:S; EggNog:ENOG410PQ0G; TransMembrane:1 (n2-9c13/14o37-61i) AKAW2_21142A COG:S; EggNog:ENOG410PR8S AKAW2_21143S COG:S; EggNog:ENOG410PG3A; InterPro:IPR029636; TransMembrane:2 (o20-40i61-79o); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_process: GO:0006113 - fermentation [Evidence IEA] AKAW2_21144A COG:M; EggNog:ENOG410Q1IT; InterPro:IPR001173,IPR029044; PFAM:PF00535,PF13641; TransMembrane:2 (i21-38o44-64i) AKAW2_21145S COG:J; EggNog:ENOG410PF9T; InterPro:IPR005517,IPR035647,IPR005225,IPR031157, IPR041095,IPR027417,IPR000640,IPR000795,IPR004161, IPR020568,IPR014721,IPR009000; PFAM:PF14492,PF03764,PF00009,PF00679,PF03144; go_function: GO:0003924 - GTPase activity [Evidence IEA]; go_function: GO:0005525 - GTP binding [Evidence IEA] AKAW2_21146S COG:S; EggNog:ENOG410QECC; InterPro:IPR000504,IPR036483,IPR035979,IPR012677, IPR002483,IPR000571; PFAM:PF01480,PF00076; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0046872 - metal ion binding [Evidence IEA]; go_process: GO:0006397 - mRNA processing [Evidence IEA] AKAW2_21147A COG:S; EggNog:ENOG410PPMZ; InterPro:IPR025331; PFAM:PF14021; SECRETED:SignalP(1-20) AKAW2_21148A COG:S; EggNog:ENOG410PPMZ; InterPro:IPR025331; PFAM:PF14021; SECRETED:SignalP(1-24) AKAW2_21149A COG:G; EggNog:ENOG410QEC4; InterPro:IPR004360,IPR037523,IPR029068; PFAM:PF00903 AKAW2_21150A COG:S; EggNog:ENOG410Q0GV AKAW2_21151A BUSCO:EOG092617AN; COG:J; EggNog:ENOG410PGRG; InterPro:IPR027417,IPR039761,IPR037875,IPR030387, IPR007034,IPR012948; PFAM:PF08142,PF04950; go_component: GO:0005634 - nucleus [Evidence IEA]; go_function: GO:0005525 - GTP binding [Evidence IEA]; go_process: GO:0042254 - ribosome biogenesis [Evidence IEA] AKAW2_21152S COG:S; EggNog:ENOG410PFJJ; InterPro:IPR018959; PFAM:PF09347 AKAW2_21153S COG:P; EggNog:ENOG410PHE6; InterPro:IPR003855; PFAM:PF02705; TransMembrane:12 (i74-98o110-131i198-216o236-255i267-287o313-332i344- 365o385-415i436-456o462-488i495-515o521-539i); go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0015079 - potassium ion transmembrane transporter activity [Evidence IEA]; go_process: GO:0071805 - potassium ion transmembrane transport [Evidence IEA] AKAW2_21154A COG:S; EggNog:ENOG410PSEW; InterPro:IPR037045 AKAW2_21155S COG:T; EggNog:ENOG410PM14; InterPro:IPR003594,IPR018955,IPR036890,IPR036784, IPR039028,IPR004358,IPR005467; PFAM:PF10436,PF02518; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0016772 - transferase activity, transferring phosphorus-containing groups [Evidence IEA]; go_process: GO:0016310 - phosphorylation [Evidence IEA] AKAW2_21156A COG:S; EggNog:ENOG410Q0A5; InterPro:IPR042183,IPR036148,IPR042188,IPR005656; PFAM:PF03972; go_function: GO:0016829 - lyase activity [Evidence IEA] AKAW2_21157A COG:S; EggNog:ENOG410PFDV; InterPro:IPR001736,IPR025202,IPR001202; PFAM:PF13091; TransMembrane:1 (o15-38i); go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_21158S COG:E; EggNog:ENOG410PJA4; InterPro:IPR012001,IPR012000,IPR011766,IPR029061, IPR029035; PFAM:PF02775,PF02776,PF00205; go_function: GO:0000287 - magnesium ion binding [Evidence IEA]; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0030976 - thiamine pyrophosphate binding [Evidence IEA] AKAW2_21159A COG:S; EggNog:ENOG410PU9M; InterPro:IPR006680,IPR032466,IPR032465; PFAM:PF04909; go_function: GO:0016787 - hydrolase activity [Evidence IEA]; go_function: GO:0016831 - carboxy-lyase activity [Evidence IEA] AKAW2_21160S COG:E; EggNog:ENOG410PIX0; InterPro:IPR004839,IPR015424,IPR015421; PFAM:PF00155; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0030170 - pyridoxal phosphate binding [Evidence IEA]; go_process: GO:0009058 - biosynthetic process [Evidence IEA] AKAW2_21161S COG:T; EggNog:ENOG410PHC2; InterPro:IPR017441,IPR008271,IPR000719,IPR011009; PFAM:PF07714,PF00069; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_21162S COG:S; EggNog:ENOG410PY0V AKAW2_21163S COG:T; EggNog:ENOG410PJ6N; InterPro:IPR017441,IPR008271,IPR000719,IPR011009; PFAM:PF07714,PF00069; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_21164S COG:O; EggNog:ENOG410PP17; InterPro:IPR016135,IPR000608; PFAM:PF00179,PF14461 AKAW2_21165A COG:C; EggNog:ENOG410PJIG; InterPro:IPR001135,IPR014029,IPR022885,IPR038290, IPR029014; PFAM:PF00346; go_function: GO:0016651 - oxidoreductase activity, acting on NAD(P)H [Evidence IEA]; go_function: GO:0048038 - quinone binding [Evidence IEA]; go_function: GO:0051287 - NAD binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_21166S BUSCO:EOG09263CLY; COG:K; EggNog:ENOG410PI11; InterPro:IPR036603,IPR001514,IPR011262,IPR011263, IPR036643,IPR033901; PFAM:PF01193,PF01000; go_function: GO:0001054 - RNA polymerase I activity [Evidence IEA]; go_function: GO:0001056 - RNA polymerase III activity [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0003899 - DNA-directed 5'-3' RNA polymerase activity [Evidence IEA]; go_function: GO:0046983 - protein dimerization activity [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA] AKAW2_21167A COG:O; EggNog:ENOG410PIEM; InterPro:IPR035985,IPR000594,IPR014929,IPR030468, IPR023318; PFAM:PF00899,PF08825; go_function: GO:0008641 - ubiquitin-like modifier activating enzyme activity [Evidence IEA]; go_function: GO:0019781 - NEDD8 activating enzyme activity [Evidence IEA]; go_process: GO:0045116 - protein neddylation [Evidence IEA] AKAW2_21168S BUSCO:EOG09263YUI; COG:S; EggNog:ENOG410PJ5W; InterPro:IPR038528,IPR019337; PFAM:PF10193 AKAW2_21169A COG:S; EggNog:ENOG410PK7F; InterPro:IPR011009 AKAW2_21171A BUSCO:EOG09261LV7; COG:Q,U; EggNog:ENOG410QEEH; InterPro:IPR043127,IPR001619,IPR027121,IPR036045, IPR043155,IPR043154,IPR027482; PFAM:PF00995; TransMembrane:1 (o604-624i); go_process: GO:0006904 - vesicle docking involved in exocytosis [Evidence IEA]; go_process: GO:0016192 - vesicle-mediated transport [Evidence IEA] AKAW2_21172S COG:U; EggNog:ENOG410QE0C; InterPro:IPR000727 AKAW2_21173S BUSCO:EOG092608T8; COG:A; EggNog:ENOG410PH7G; InterPro:IPR016024,IPR011989,IPR021133,IPR015016, IPR038737; PFAM:PF08920; TransMembrane:1 (o562-583i); go_function: GO:0003729 - mRNA binding [Evidence IEA]; go_process: GO:0000245 - spliceosomal complex assembly [Evidence IEA] AKAW2_21174S COG:C; EggNog:ENOG410PFQU; InterPro:IPR003953,IPR036188,IPR027477; PFAM:PF00890,PF01266 AKAW2_21175S COG:K; EggNog:ENOG410PN3T; InterPro:IPR036236,IPR013087; PFAM:PF00096,PF12874 AKAW2_21176S COG:S; EggNog:ENOG410PRHJ; InterPro:IPR040746,IPR003034,IPR036361; PFAM:PF02037,PF18592 AKAW2_21177S COG:S; EggNog:ENOG410PFSK; InterPro:IPR029063 AKAW2_21179S CAZy:CBM21; COG:O,T; EggNog:ENOG410PGU8; InterPro:IPR038175,IPR005036; PFAM:PF16760,PF03370; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_21180S COG:B; EggNog:ENOG410PPJQ; InterPro:IPR009072,IPR019809,IPR001951,IPR035425; PFAM:PF15511,PF02969; go_component: GO:0000786 - nucleosome [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0046982 - protein heterodimerization activity [Evidence IEA] AKAW2_21181S COG:C; EggNog:ENOG410PNDX; InterPro:IPR018108,IPR023395; PFAM:PF00153; TransMembrane:2 (o212-239i251-272o) AKAW2_21182S COG:O; EggNog:ENOG410PKG5; InterPro:IPR001841,IPR027370,IPR017907,IPR036028, IPR001452,IPR013083; PFAM:PF13923,PF00097,PF13445,PF13639; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_21183A COG:U; EggNog:ENOG410PJTM; InterPro:IPR001464,IPR018252,IPR037104,IPR018502; PFAM:PF00191; go_function: GO:0005509 - calcium ion binding [Evidence IEA]; go_function: GO:0005544 - calcium-dependent phospholipid binding [Evidence IEA] AKAW2_21184S COG:A; EggNog:ENOG410PJWC; InterPro:IPR001841,IPR017907,IPR000571,IPR013083, IPR039971,IPR036855; PFAM:PF13923,PF13920,PF00642,PF00097,PF13445; go_function: GO:0046872 - metal ion binding [Evidence IEA] AKAW2_21185S SECRETED:SignalP(1-29); TransMembrane:3 (n7-17c22/23o46-63i70-91o97-113i) AKAW2_21186A COG:S; EggNog:ENOG410PIN6; InterPro:IPR036188,IPR002938; PFAM:PF01494; SMCOG1087:hypothetical protein; antiSMASH:Cluster_2.5; go_function: GO:0071949 - FAD binding [Evidence IEA] AKAW2_21187S COG:S; EggNog:ENOG410PURK; InterPro:IPR036864,IPR001138; PFAM:PF00172; antiSMASH:Cluster_2.5; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_21188A COG:I; EggNog:ENOG410PP6P; InterPro:IPR033118,IPR007905; PFAM:PF05241; TransMembrane:5 (o66-88i100-127o177-198i218-237o252-275i); antiSMASH:Cluster_2.5; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0047750 - cholestenol delta-isomerase activity [Evidence IEA]; go_process: GO:0016125 - sterol metabolic process [Evidence IEA] AKAW2_21189S COG:S; EggNog:ENOG410PXMS; antiSMASH:Cluster_2.5 AKAW2_21190S COG:S; EggNog:ENOG410Q1MV; antiSMASH:Cluster_2.5 AKAW2_21191S COG:S; EggNog:ENOG410PZ4H; antiSMASH:Cluster_2.5 AKAW2_21192A COG:Q; EggNog:ENOG410PM8C; InterPro:IPR036396; antiSMASH:Cluster_2.5; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_21193A COG:C,H; EggNog:ENOG410PMET; InterPro:IPR003953,IPR036188; SMCOG1087:hypothetical protein; TransMembrane:1 (o20-39i); antiSMASH:Cluster_2.5 AKAW2_21194S COG:I; EggNog:ENOG410PWDM; InterPro:IPR000873,IPR020845,IPR009081,IPR036736, IPR020806,IPR023213,IPR042099,IPR010071,IPR001242; PFAM:PF00501,PF00668,PF00550; SMCOG1002:AMP-dependent synthetase and ligase; antiSMASH:Cluster_2.5; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0031177 - phosphopantetheine binding [Evidence IEA] AKAW2_21195A COG:S; EggNog:ENOG410Q2BF; antiSMASH:Cluster_2.5 AKAW2_21196A COG:J; EggNog:ENOG410PSNW; InterPro:IPR016340; PFAM:PF09784; antiSMASH:Cluster_2.5 AKAW2_21197S COG:I; EggNog:ENOG410PGF9; InterPro:IPR000872,IPR002123; PFAM:PF01553; antiSMASH:Cluster_2.5; go_function: GO:0016746 - transferase activity, transferring acyl groups [Evidence IEA]; go_process: GO:0006644 - phospholipid metabolic process [Evidence IEA] AKAW2_21199S COG:I; EggNog:ENOG410PGF9; InterPro:IPR032675; antiSMASH:Cluster_2.5 AKAW2_21198A COG:J; EggNog:ENOG410PFWA; InterPro:IPR027417,IPR014014,IPR014001,IPR001650, IPR011545; PFAM:PF00271; SMCOG1122:ATP-dependent RNA helicase; antiSMASH:Cluster_2.5; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0004386 - helicase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA] AKAW2_21200S antiSMASH:Cluster_2.5 AKAW2_21201A COG:S; EggNog:ENOG410PRMZ; TransMembrane:1 (o61-83i) AKAW2_21202S COG:S; EggNog:ENOG410PVQ8 AKAW2_21203A COG:Q; EggNog:ENOG410PFGP; InterPro:IPR043926,IPR027417,IPR003593,IPR017871, IPR003439,IPR013525; PFAM:PF01061,PF00005; TransMembrane:6 (i369-391o403-426i447-470o482-503i510-532o607-628i); go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA]; go_function: GO:0042626 - ATPase-coupled transmembrane transporter activity [Evidence IEA] AKAW2_21204A CAZy:GH28; COG:G; EggNog:ENOG410PFRD; InterPro:IPR000743,IPR012334,IPR006626,IPR011050; PFAM:PF00295; SECRETED:SignalP(1-20); go_function: GO:0004650 - polygalacturonase activity [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_21205A COG:J; EggNog:ENOG410PGU2; InterPro:IPR035684,IPR005148,IPR009080,IPR001412, IPR001278,IPR014729,IPR008909,IPR036695; PFAM:PF03485,PF00750,PF05746; go_component: GO:0005737 - cytoplasm [Evidence IEA]; go_function: GO:0000166 - nucleotide binding [Evidence IEA]; go_function: GO:0004812 - aminoacyl-tRNA ligase activity [Evidence IEA]; go_function: GO:0004814 - arginine-tRNA ligase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006418 - tRNA aminoacylation for protein translation [Evidence IEA]; go_process: GO:0006420 - arginyl-tRNA aminoacylation [Evidence IEA] AKAW2_21206S COG:S; EggNog:ENOG410PS7C; InterPro:IPR027483,IPR002498,IPR023610,IPR027484; PFAM:PF01504; TransMembrane:1 (o29-47i); go_function: GO:0016307 - phosphatidylinositol phosphate kinase activity [Evidence IEA]; go_process: GO:0046488 - phosphatidylinositol metabolic process [Evidence IEA] AKAW2_21207A COG:M; EggNog:ENOG410PFSQ; InterPro:IPR001834,IPR001709,IPR001433,IPR017927, IPR008333,IPR017938,IPR039261; PFAM:PF00175,PF00970; TransMembrane:1 (o30-47i); go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_21208S COG:S; EggNog:ENOG410PNUE; InterPro:IPR022036; PFAM:PF12239 AKAW2_21209A COG:D; EggNog:ENOG410PHGY; InterPro:IPR010935,IPR001315,IPR003395,IPR027417, IPR036277,IPR024704; PFAM:PF06470,PF13304,PF02463; go_component: GO:0005694 - chromosome [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0042981 - regulation of apoptotic process [Evidence IEA]; go_process: GO:0051276 - chromosome organization [Evidence IEA] AKAW2_21210S COG:D,T; EggNog:ENOG410PG2F; InterPro:IPR018935,IPR000687,IPR011009,IPR017407; PFAM:PF01163; go_function: GO:0004674 - protein serine/threonine kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA] AKAW2_21212A COG:T; EggNog:ENOG410PQ9E; InterPro:IPR000719,IPR011009; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_21213S COG:T; EggNog:ENOG410PQCF; InterPro:IPR008271,IPR002110,IPR020683,IPR036770, IPR000719,IPR011009; PFAM:PF12796,PF00023,PF07714,PF00069,PF13637, PF13606; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_21214A COG:O; EggNog:ENOG410PHBJ; InterPro:IPR007240; PFAM:PF04108; go_process: GO:0006914 - autophagy [Evidence IEA] AKAW2_21215S BUSCO:EOG09260KIY; COG:K; EggNog:ENOG410QDQX; InterPro:IPR001810,IPR036322,IPR015943,IPR001680, IPR036047,IPR019775,IPR020472,IPR017986; PFAM:PF00646,PF00400,PF12937; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_21216A COG:S; EggNog:ENOG410Q7JS AKAW2_21217S COG:O; EggNog:ENOG410PVN0; InterPro:IPR027417,IPR003593,IPR003959; PFAM:PF00004; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA] AKAW2_21219S TransMembrane:1 (i84-106o) AKAW2_21221A COG:S; EggNog:ENOG410PMGJ; InterPro:IPR036609,IPR013951; PFAM:PF08642; go_process: GO:0016575 - histone deacetylation [Evidence IEA] AKAW2_21222A COG:S; EggNog:ENOG410PITV; TransMembrane:1 (i82-108o) AKAW2_21223S COG:E,O; EggNog:ENOG410PG21; InterPro:IPR018202,IPR001563,IPR033124,IPR029058; MEROPS:MER0001944; PFAM:PF00450; SECRETED:SignalP(1-18); go_function: GO:0004185 - serine-type carboxypeptidase activity [Evidence IEA]; go_process: GO:0006508 - proteolysis [Evidence IEA] AKAW2_21224A CAZy:CE10; COG:I; EggNog:ENOG410PGXG; InterPro:IPR029058,IPR013094; MEROPS:MER0033274; PFAM:PF07859; TransMembrane:2 (o12-30i51-71o); go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_21225A COG:U; EggNog:ENOG410PG9U; InterPro:IPR003492,IPR018460,IPR036259; PFAM:PF02487; TransMembrane:10 (i41-61o73-93i100-120o132-152i159-182o194-212i281-299o319- 337i349-369o375-394i); go_component: GO:0016020 - membrane [Evidence IEA] AKAW2_21226S BUSCO:EOG09265K4K; COG:S; EggNog:ENOG410PPXV; InterPro:IPR012875; PFAM:PF07896 AKAW2_21227S COG:S; EggNog:ENOG410PUJ5; InterPro:IPR011009,IPR002575; PFAM:PF01636 AKAW2_21228A COG:I; EggNog:ENOG410PG5B; InterPro:IPR013785,IPR000891,IPR043594; PFAM:PF00682; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0016833 - oxo-acid-lyase activity [Evidence IEA] AKAW2_21229S BUSCO:EOG09261X9E; COG:J; EggNog:ENOG410PH0C; InterPro:IPR016435,IPR042263,IPR042264,IPR042265, IPR035435; PFAM:PF01866; go_process: GO:0017183 - peptidyl-diphthamide biosynthetic process from peptidyl-histidine [Evidence IEA] AKAW2_21230A COG:S; EggNog:ENOG410PQHX; InterPro:IPR036427,IPR001487; PFAM:PF00439; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_21231A COG:S; EggNog:ENOG410Q2W6; InterPro:IPR002110,IPR036770,IPR020683; PFAM:PF12796,PF00023,PF13637; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_21232A COG:G; EggNog:ENOG410PI4J; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i35-55o75-94i106-125o131-152i164-183o195-215i248-272o292- 313i320-337o343-361i382-402o422-443i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_21233A COG:Q; EggNog:ENOG410PG4C; InterPro:IPR002925,IPR029058; PFAM:PF01738; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_21234S COG:S; EggNog:ENOG410PYHK AKAW2_21235S COG:G; EggNog:ENOG410PGNA; InterPro:IPR008928,IPR031335,IPR004888; go_function: GO:0004573 - mannosyl-oligosaccharide glucosidase activity [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA]; go_process: GO:0009311 - oligosaccharide metabolic process [Evidence IEA] AKAW2_21236A COG:M; EggNog:ENOG410PFZI; InterPro:IPR029063; PFAM:PF02353,PF08241,PF13649,PF13489; TransMembrane:2 (o58-78i85-103o) AKAW2_21237A BUSCO:EOG09264KDO; COG:C; EggNog:ENOG410PNEN; InterPro:IPR000711,IPR026015,IPR020781; PFAM:PF00213; go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0046933 - proton-transporting ATP synthase activity, rotational mechanism [Evidence IEA]; go_process: GO:0015986 - ATP synthesis coupled proton transport [Evidence IEA] AKAW2_21238A COG:D; EggNog:ENOG410PK5C; InterPro:IPR005301,IPR036703; PFAM:PF03637; SECRETED:SignalP(1-17) AKAW2_21239A COG:U; EggNog:ENOG410PGWE; InterPro:IPR014848,IPR014752; PFAM:PF08737 AKAW2_21240A COG:O; EggNog:ENOG410PR35; InterPro:IPR010487 AKAW2_21241S COG:S; EggNog:ENOG410PKGW; InterPro:IPR015943,IPR001680,IPR036322,IPR017986; PFAM:PF00400; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_21242S COG:S; EggNog:ENOG410PQ0N; InterPro:IPR036291,IPR002347; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_21243S COG:Q; EggNog:ENOG410PJ6C; InterPro:IPR036291,IPR002347; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_21244A COG:S; EggNog:ENOG410PXM0; InterPro:IPR039057; go_process: GO:0090173 - regulation of synaptonemal complex assembly [Evidence IEA] AKAW2_21245A COG:S; EggNog:ENOG410PXM0; InterPro:IPR039057,IPR013940; PFAM:PF08631; go_process: GO:0051321 - meiotic cell cycle [Evidence IEA]; go_process: GO:0090173 - regulation of synaptonemal complex assembly [Evidence IEA] AKAW2_21246A COG:S; EggNog:ENOG410PH9D; InterPro:IPR036864,IPR001138; PFAM:PF00172; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_21247A COG:S; EggNog:ENOG410PSNI; InterPro:IPR025212; PFAM:PF13094 AKAW2_21248A COG:K; EggNog:ENOG410PN7P; InterPro:IPR011598,IPR036638; PFAM:PF00010; go_function: GO:0046983 - protein dimerization activity [Evidence IEA] AKAW2_21249S COG:S; EggNog:ENOG410PIVY; InterPro:IPR026749; TransMembrane:7 (o69-93i114-131o177-197i217-237o329-347i359-380o400-421i) AKAW2_21250S COG:O; EggNog:ENOG410PG5S; InterPro:IPR007533,IPR023471; PFAM:PF04442; TransMembrane:1 (i64-82o); go_function: GO:0005507 - copper ion binding [Evidence IEA] AKAW2_21251S BUSCO:EOG09263OQH; COG:L; EggNog:ENOG410PGQJ; InterPro:IPR008921,IPR027417,IPR003593; PFAM:PF00004,PF13177; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_process: GO:0006260 - DNA replication [Evidence IEA] AKAW2_21252S COG:S; EggNog:ENOG410Q1UP AKAW2_21253A BUSCO:EOG09264T3S; COG:J; EggNog:ENOG410PFN9; InterPro:IPR020798,IPR036920,IPR016180,IPR000114; PFAM:PF00252; go_component: GO:0005840 - ribosome [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_function: GO:0019843 - rRNA binding [Evidence IEA]; go_process: GO:0006412 - translation [Evidence IEA] AKAW2_21254S BUSCO:EOG09261NW2; COG:L; EggNog:ENOG410PH5D; InterPro:IPR036420,IPR003959,IPR012178,IPR001357, IPR027417,IPR003593,IPR013725,IPR008921; PFAM:PF00533,PF13401,PF00004,PF08519; go_component: GO:0005663 - DNA replication factor C complex [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0003689 - DNA clamp loader activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA]; go_process: GO:0006260 - DNA replication [Evidence IEA]; go_process: GO:0006281 - DNA repair [Evidence IEA] AKAW2_21255S COG:T; EggNog:ENOG410PJR9; InterPro:IPR031567,IPR031313,IPR011993,IPR008828; PFAM:PF16979,PF16978; go_component: GO:0031932 - TORC2 complex [Evidence IEA] AKAW2_21256S COG:T; EggNog:ENOG410PHM9; InterPro:IPR017441,IPR008271,IPR000961,IPR000719, IPR011009; PFAM:PF07714,PF00069; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0004674 - protein serine/threonine kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_21257A BUSCO:EOG09265PJ3; COG:U; EggNog:ENOG410PS0T; InterPro:IPR004217,IPR035427,IPR039238; PFAM:PF02953; go_component: GO:0005758 - mitochondrial intermembrane space [Evidence IEA]; go_process: GO:0072321 - chaperone-mediated protein transport [Evidence IEA] AKAW2_21258S BUSCO:EOG092628SP; COG:U; EggNog:ENOG410PHCK; InterPro:IPR005052,IPR013320; PFAM:PF03388; SECRETED:SignalP(1-23); TransMembrane:1 (n6-16c23/24o293-317i); go_component: GO:0016020 - membrane [Evidence IEA] AKAW2_21259A COG:S; EggNog:ENOG410PN7K; InterPro:IPR038753; go_process: GO:0007249 - I-kappaB kinase/NF-kappaB signaling [Evidence IEA] AKAW2_21260S COG:S; EggNog:ENOG410PKSN; InterPro:IPR018800; PFAM:PF10253 AKAW2_21261A BUSCO:EOG0926004Z; COG:S; EggNog:ENOG410PFRP; InterPro:IPR040848,IPR011704,IPR002035,IPR027417, IPR003593,IPR012099,IPR041190,IPR036465; PFAM:PF17865,PF17867,PF07726,PF07728; go_component: GO:0005634 - nucleus [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA]; go_process: GO:0000027 - ribosomal large subunit assembly [Evidence IEA] AKAW2_21262S COG:P; EggNog:ENOG410PKWP; InterPro:IPR001807,IPR014743,IPR000644; PFAM:PF00654; TransMembrane:12 (i173-191o255-279i300-323o329-345i357-381o393-413i434- 455o467-486i529-549o555-574i594-615o621-645i); go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0005247 - voltage-gated chloride channel activity [Evidence IEA]; go_process: GO:0006821 - chloride transport [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_21263S COG:S; EggNog:ENOG410PMAC; InterPro:IPR024638,IPR024637,IPR042326,IPR006569, IPR008942; PFAM:PF04818,PF12350,PF12243; go_component: GO:0070692 - CTDK-1 complex [Evidence IEA]; go_process: GO:0032786 - positive regulation of DNA-templated transcription, elongation [Evidence IEA] AKAW2_21264S COG:S; EggNog:ENOG410PTFH; InterPro:IPR013268; PFAM:PF08297; go_function: GO:0030515 - snoRNA binding [Evidence IEA]; go_process: GO:0006364 - rRNA processing [Evidence IEA] AKAW2_21265S COG:S; EggNog:ENOG410PFZK; InterPro:IPR003734; PFAM:PF02582; TransMembrane:1 (o505-528i) AKAW2_21266A COG:S; EggNog:ENOG410PNT1 AKAW2_21267A COG:C; EggNog:ENOG410PFFI; InterPro:IPR018108,IPR023395; PFAM:PF00153; TransMembrane:2 (i217-235o255-272i) AKAW2_21268A COG:K; EggNog:ENOG410PY8Z; InterPro:IPR036864,IPR001138; PFAM:PF00172; TransMembrane:1 (o450-470i); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_21269A COG:S; EggNog:ENOG410PJB9; InterPro:IPR001810,IPR036322,IPR015943,IPR001680, IPR036047,IPR019775,IPR020472,IPR017986; PFAM:PF00400,PF12937; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_21270A COG:P; EggNog:ENOG410PM4W; InterPro:IPR003689; PFAM:PF02535; TransMembrane:8 (o6-28i35-55o160-177i230-249o255-280i292-315o327-345i382- 400o); go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0046873 - metal ion transmembrane transporter activity [Evidence IEA]; go_process: GO:0030001 - metal ion transport [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_21271A COG:I; EggNog:ENOG410PKU0; InterPro:IPR006176,IPR022694,IPR006108,IPR036291, IPR008927,IPR013328; PFAM:PF02737,PF00725; go_function: GO:0003857 - 3-hydroxyacyl-CoA dehydrogenase activity [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0070403 - NAD+ binding [Evidence IEA]; go_process: GO:0006631 - fatty acid metabolic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_21272S BUSCO:EOG09263EVJ; COG:B; EggNog:ENOG410PHRB; InterPro:IPR037113,IPR019467,IPR017380,IPR016181; PFAM:PF10394; go_component: GO:0005634 - nucleus [Evidence IEA]; go_function: GO:0004402 - histone acetyltransferase activity [Evidence IEA]; go_process: GO:0006325 - chromatin organization [Evidence IEA]; go_process: GO:0006348 - chromatin silencing at telomere [Evidence IEA]; go_process: GO:0016573 - histone acetylation [Evidence IEA] AKAW2_21273A COG:S; EggNog:ENOG410PYV6; SECRETED:SignalP(1-40); TransMembrane:1 (i100-121o) AKAW2_21274S COG:A; EggNog:ENOG410PQRW; InterPro:IPR027141,IPR034101,IPR010920,IPR001163; PFAM:PF01423; go_process: GO:0000398 - mRNA splicing, via spliceosome [Evidence IEA]; go_process: GO:0000956 - nuclear-transcribed mRNA catabolic process [Evidence IEA]; go_process: GO:0006396 - RNA processing [Evidence IEA] AKAW2_21275S COG:S; EggNog:ENOG410PMY6; InterPro:IPR033443,IPR002885,IPR011990; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_21276S COG:S; EggNog:ENOG410Q2VG; SECRETED:SignalP(1-19) AKAW2_21277S BUSCO:EOG09262341; COG:V; EggNog:ENOG410QD6P; InterPro:IPR029023,IPR003595,IPR016130,IPR029021, IPR000340; go_function: GO:0004725 - protein tyrosine phosphatase activity [Evidence IEA]; go_function: GO:0008138 - protein tyrosine/serine/threonine phosphatase activity [Evidence IEA]; go_process: GO:0016311 - dephosphorylation [Evidence IEA] AKAW2_21278A COG:I; EggNog:ENOG410PJSF; InterPro:IPR016035,IPR002642; PFAM:PF01735; go_function: GO:0004620 - phospholipase activity [Evidence IEA]; go_process: GO:0009395 - phospholipid catabolic process [Evidence IEA] AKAW2_21279S BUSCO:EOG092612J3; COG:U; EggNog:ENOG410PIGT; InterPro:IPR016159,IPR004140; PFAM:PF03081; go_component: GO:0000145 - exocyst [Evidence IEA]; go_process: GO:0006887 - exocytosis [Evidence IEA] AKAW2_21280S COG:F; EggNog:ENOG410PIRI; InterPro:IPR022761,IPR004769,IPR024083,IPR020557, IPR008948,IPR000362; PFAM:PF00206; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0004018 - N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity [Evidence IEA]; go_process: GO:0009152 - purine ribonucleotide biosynthetic process [Evidence IEA] AKAW2_21281A COG:S; EggNog:ENOG410PWQS; TransMembrane:1 (i41-61o) AKAW2_21283S COG:T; EggNog:ENOG410PHX7; InterPro:IPR005467,IPR003594,IPR036890,IPR018955, IPR039028,IPR004358,IPR036784; PFAM:PF10436,PF02518; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0016772 - transferase activity, transferring phosphorus-containing groups [Evidence IEA]; go_process: GO:0016310 - phosphorylation [Evidence IEA] AKAW2_21284A COG:S; EggNog:ENOG410PZK4 AKAW2_21285A COG:G; EggNog:ENOG410PH77; InterPro:IPR000757,IPR013320,IPR005629; PFAM:PF03935; TransMembrane:1 (i187-210o); go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA]; go_process: GO:0006078 - (1->6)-beta-D-glucan biosynthetic process [Evidence IEA] AKAW2_21287A COG:S; EggNog:ENOG410PSDT AKAW2_21288A COG:J; EggNog:ENOG410PGH7; InterPro:IPR000597,IPR009000,IPR019926; PFAM:PF00297; go_component: GO:0005840 - ribosome [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_process: GO:0006412 - translation [Evidence IEA] AKAW2_21289A BUSCO:EOG09261RFF; COG:S; EggNog:ENOG410QDSH; InterPro:IPR011990,IPR019734,IPR013026,IPR001440; PFAM:PF07719,PF00515,PF13176,PF13181,PF13428, PF12895,PF13432,PF13174; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_21290A SECRETED:SignalP(1-18) AKAW2_21291S COG:S; EggNog:ENOG410PSPG; TransMembrane:2 (o199-221i289-316o) AKAW2_21292A BUSCO:EOG092608AV; COG:S; EggNog:ENOG410PIGM; InterPro:IPR016024,IPR012978; PFAM:PF08161 AKAW2_21293A COG:A; EggNog:ENOG410PR4U; InterPro:IPR034104,IPR010920,IPR001163; PFAM:PF01423; go_process: GO:0000956 - nuclear-transcribed mRNA catabolic process [Evidence IEA] AKAW2_21294A COG:S; EggNog:ENOG410PY10 AKAW2_21295A COG:K; EggNog:ENOG410PSX7; InterPro:IPR036236,IPR013087 AKAW2_21296S COG:S; EggNog:ENOG410PSGI; InterPro:IPR025718,IPR038291,IPR024145; PFAM:PF13867; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_21297A COG:U; EggNog:ENOG410PGNU; InterPro:IPR038499,IPR025304,IPR004328; PFAM:PF13949,PF03097; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_21298A BUSCO:EOG09263E49; COG:O; EggNog:ENOG410PGPS; InterPro:IPR008971,IPR002939,IPR001623,IPR036869, IPR012724,IPR001305,IPR036410,IPR018253; PFAM:PF00684,PF00226,PF01556; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0031072 - heat shock protein binding [Evidence IEA]; go_function: GO:0051082 - unfolded protein binding [Evidence IEA]; go_process: GO:0006457 - protein folding [Evidence IEA]; go_process: GO:0009408 - response to heat [Evidence IEA] AKAW2_21299S BUSCO:EOG09260RRN; COG:O; EggNog:ENOG410PFUX; InterPro:IPR027065,IPR003959,IPR008268,IPR008269, IPR027417,IPR003593,IPR004815,IPR015947,IPR027503, IPR020568,IPR003111,IPR014721; MEROPS:MER0000496; PFAM:PF00004,PF05362,PF07728,PF07724,PF02190; go_function: GO:0004176 - ATP-dependent peptidase activity [Evidence IEA]; go_function: GO:0004252 - serine-type endopeptidase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA]; go_process: GO:0006508 - proteolysis [Evidence IEA]; go_process: GO:0006515 - protein quality control for misfolded or incompletely synthesized proteins [Evidence IEA]; go_process: GO:0030163 - protein catabolic process [Evidence IEA] AKAW2_21300S SECRETED:SignalP(1-19) AKAW2_21301S COG:T; EggNog:ENOG410PHAH; InterPro:IPR000719,IPR011009; PFAM:PF07714,PF00069; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_21302A COG:H; EggNog:ENOG410PGH6; InterPro:IPR036627,IPR003495,IPR027417,IPR011629; PFAM:PF02492,PF07683 AKAW2_21303S COG:D; EggNog:ENOG410PKJV; InterPro:IPR005301,IPR036703; PFAM:PF03637 AKAW2_21304S COG:F; EggNog:ENOG410PNV8; InterPro:IPR011146,IPR039383,IPR001310,IPR036265; PFAM:PF01230; go_function: GO:0003824 - catalytic activity [Evidence IEA] AKAW2_21305A COG:S; EggNog:ENOG410PHDD; InterPro:IPR006674,IPR039356,IPR003607; PFAM:PF12917,PF13023; go_function: GO:0002953 - 5'-deoxynucleotidase activity [Evidence IEA] AKAW2_21306S COG:S; EggNog:ENOG410PHN9; InterPro:IPR028163; PFAM:PF14661 AKAW2_21307A COG:L; EggNog:ENOG410PG1K; InterPro:IPR038765,IPR018328,IPR018325,IPR018326, IPR018327,IPR042488,IPR004583; PFAM:PF10404,PF03835,PF10403,PF10405; go_component: GO:0005634 - nucleus [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0003684 - damaged DNA binding [Evidence IEA]; go_process: GO:0006289 - nucleotide-excision repair [Evidence IEA] AKAW2_21308S COG:S; EggNog:ENOG410PPR9; InterPro:IPR036291,IPR003781; PFAM:PF13380 AKAW2_21309S COG:S; EggNog:ENOG410PWQR AKAW2_21310A SECRETED:SignalP(1-18) AKAW2_21311A COG:G; EggNog:ENOG410PVAN; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i81-102o122-141i153-173o179-197i209-232o238-258i306- 331o351-370i391-410o416-437i449-472o484-504i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_21313A COG:I; EggNog:ENOG410PJF0; InterPro:IPR029154,IPR015815,IPR036291,IPR006115, IPR008927,IPR013328; PFAM:PF03807,PF03446,PF14833,PF01488; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0050661 - NADP binding [Evidence IEA]; go_function: GO:0051287 - NAD binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_21314A COG:S; EggNog:ENOG410PN1E AKAW2_21315A COG:G; EggNog:ENOG410PFTW; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690,PF00083; TransMembrane:12 (i70-87o107-126i138-155o167-188i195-218o230-251i303- 327o339-359i380-401o407-431i438-463o475-497i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_21316A COG:S; EggNog:ENOG410PQDY; InterPro:IPR001810,IPR036047; PFAM:PF00646,PF12937; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_21317S COG:C; EggNog:ENOG410PFUG; InterPro:IPR001937,IPR019779,IPR005849,IPR005850, IPR036265; PFAM:PF01087,PF02744; go_function: GO:0008108 - UDP-glucose:hexose-1-phosphate uridylyltransferase activity [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006012 - galactose metabolic process [Evidence IEA]; go_process: GO:0033499 - galactose catabolic process via UDP-galactose [Evidence IEA] AKAW2_21318A BUSCO:EOG092655IF; COG:S; EggNog:ENOG410PQX8; InterPro:IPR005352; PFAM:PF03694; TransMembrane:3 (i49-66o144-163i170-188o); go_component: GO:0016021 - integral component of membrane [Evidence IEA] AKAW2_21319S BUSCO:EOG0926310O; COG:I; EggNog:ENOG410PFH9; InterPro:IPR002347,IPR027533,IPR036291,IPR020904; PFAM:PF00106,PF13561; TransMembrane:3 (o29-55i201-220o297-319i); go_component: GO:0005783 - endoplasmic reticulum [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0045703 - ketoreductase activity [Evidence IEA]; go_process: GO:0030497 - fatty acid elongation [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_21320S COG:A; EggNog:ENOG410PFSV; InterPro:IPR005829,IPR005828,IPR003663,IPR036259, IPR020846; PFAM:PF00083,PF07690; TransMembrane:10 (i20-37o49-65i77-96o108-130i199-221o233-254i261-280o300- 322i334-357o363-384i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_21321A BUSCO:EOG092619NK; COG:S; EggNog:ENOG410PFNA; InterPro:IPR027417,IPR012973,IPR005225,IPR024926, IPR006073,IPR010674,IPR041623,IPR031167; PFAM:PF02421,PF06858,PF17835,PF08155,PF01926; go_component: GO:0005730 - nucleolus [Evidence IEA]; go_function: GO:0005525 - GTP binding [Evidence IEA] AKAW2_21322A COG:K; EggNog:ENOG410PJFM; InterPro:IPR000182,IPR016181; PFAM:PF13673,PF13508,PF00583; go_function: GO:0008080 - N-acetyltransferase activity [Evidence IEA] AKAW2_21323S COG:E; EggNog:ENOG410PJ6Z; InterPro:IPR006076,IPR036188; PFAM:PF01266; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_21324S COG:S; EggNog:ENOG410PM1R; InterPro:IPR007290; PFAM:PF04161; TransMembrane:4 (i84-103o123-145i367-384o396-418i); go_process: GO:0032366 - intracellular sterol transport [Evidence IEA] AKAW2_21325A COG:S; EggNog:ENOG410PKGM; InterPro:IPR004148,IPR027267,IPR018859; PFAM:PF03114,PF10455; go_component: GO:0005737 - cytoplasm [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_21326A COG:S; EggNog:ENOG410PQXF AKAW2_21328A COG:S; EggNog:ENOG410PHKR; InterPro:IPR036864,IPR021858,IPR001138; PFAM:PF00172; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_21329S BUSCO:EOG09263YBT; COG:A; EggNog:ENOG410PGVA; InterPro:IPR007823,IPR029063,IPR042036; PFAM:PF08241,PF05148; go_function: GO:0008168 - methyltransferase activity [Evidence IEA] AKAW2_21330A COG:O; EggNog:ENOG410PI7M; InterPro:IPR029055,IPR001353,IPR023332,IPR033812, IPR000426; MEROPS:MER0047611; PFAM:PF00227,PF10584; go_component: GO:0005839 - proteasome core complex [Evidence IEA]; go_component: GO:0019773 - proteasome core complex, alpha-subunit complex [Evidence IEA]; go_process: GO:0006511 - ubiquitin-dependent protein catabolic process [Evidence IEA]; go_process: GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process [Evidence IEA]; go_process: GO:0051603 - proteolysis involved in cellular protein catabolic process [Evidence IEA] AKAW2_21331S COG:Z; EggNog:ENOG410PJ4F; InterPro:IPR007259,IPR041470,IPR042241,IPR040457; PFAM:PF04130,PF17681; go_component: GO:0000922 - spindle pole [Evidence IEA]; go_component: GO:0005815 - microtubule organizing center [Evidence IEA]; go_function: GO:0043015 - gamma-tubulin binding [Evidence IEA]; go_process: GO:0000226 - microtubule cytoskeleton organization [Evidence IEA]; go_process: GO:0007020 - microtubule nucleation [Evidence IEA] AKAW2_21332S COG:S; EggNog:ENOG410PG9V AKAW2_21334S COG:S; EggNog:ENOG410PKVW; InterPro:IPR029063 AKAW2_21335S BUSCO:EOG09263CG4; COG:J; EggNog:ENOG410PFJP; InterPro:IPR041174,IPR004087,IPR036612,IPR024166; PFAM:PF17903; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0003723 - RNA binding [Evidence IEA] AKAW2_21336A COG:G; EggNog:ENOG410PFUJ; InterPro:IPR024671,IPR036259; PFAM:PF11700; TransMembrane:11 (o106-126i138-156o168-190i228-250o262-285i321-344o356- 377i389-409o421-440i452-477o489-511i) AKAW2_21337A COG:I; EggNog:ENOG410PWCZ; InterPro:IPR042099,IPR000873,IPR020845; PFAM:PF00501 AKAW2_21338S COG:I; EggNog:ENOG410PJ8U; InterPro:IPR016039,IPR020613,IPR020610,IPR020617, IPR020616,IPR002155; PFAM:PF00108,PF02803; TransMembrane:1 (i400-418o); go_function: GO:0016746 - transferase activity, transferring acyl groups [Evidence IEA]; go_function: GO:0016747 - transferase activity, transferring acyl groups other than amino-acyl groups [Evidence IEA] AKAW2_21339S BUSCO:EOG09264UJF; COG:U; EggNog:ENOG410PQD6; InterPro:IPR014756,IPR039670,IPR033917,IPR003172; PFAM:PF02221; SECRETED:SignalP(1-20); go_process: GO:0032366 - intracellular sterol transport [Evidence IEA] AKAW2_21340A BUSCO:EOG09265FI4; COG:C; EggNog:ENOG410PPQE; InterPro:IPR008218,IPR036906,IPR005772; PFAM:PF01990; go_component: GO:0033180 - proton-transporting V-type ATPase, V1 domain [Evidence IEA]; go_function: GO:0046961 - proton-transporting ATPase activity, rotational mechanism [Evidence IEA]; go_process: GO:0034220 - ion transmembrane transport [Evidence IEA]; go_process: GO:1902600 - proton transmembrane transport [Evidence IEA] AKAW2_21341S COG:S; EggNog:ENOG410PJAC; InterPro:IPR018819; PFAM:PF10332; TransMembrane:4 (i43-62o82-104i177-196o208-227i) AKAW2_21342S COG:U; EggNog:ENOG410PZ4R; TransMembrane:3 (o821-837i858-879o885-905i) AKAW2_21343A COG:E; EggNog:ENOG410PGGH; InterPro:IPR029041,IPR003171,IPR004621; PFAM:PF02219; go_function: GO:0004489 - methylenetetrahydrofolate reductase (NAD(P)H) activity [Evidence IEA]; go_process: GO:0006555 - methionine metabolic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_21344S CAZy:GH13; CAZy:GT5; COG:M; EggNog:ENOG410PF9V; InterPro:IPR013534,IPR006047,IPR017853; PFAM:PF08323,PF00128; SECRETED:SignalP(1-19); TransMembrane:13 (n3-14c19/20o1075-1097i1997-2019o2031-2048i2055-2077o2089- 2109i2121-2142o2167-2192i2212-2229o2249-2271i2291- 2309o2321-2341i2348-2371o2391-2414i); go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_21345A BUSCO:EOG09260SL3; COG:E; EggNog:ENOG410PH7V; InterPro:IPR004431,IPR004430,IPR033941,IPR033940, IPR001030,IPR012235,IPR018136,IPR036008,IPR015931, IPR015928,IPR000573; PFAM:PF00330,PF00694; go_component: GO:0009316 - 3-isopropylmalate dehydratase complex [Evidence IEA]; go_function: GO:0003861 - 3-isopropylmalate dehydratase activity [Evidence IEA]; go_function: GO:0051539 - 4 iron, 4 sulfur cluster binding [Evidence IEA]; go_process: GO:0009098 - leucine biosynthetic process [Evidence IEA] AKAW2_21346A BUSCO:EOG09262QS5; COG:G; EggNog:ENOG410PG65; InterPro:IPR033895,IPR000715; PFAM:PF00953; TransMembrane:9 (n17-29c34/35o44-65i86-107o143-162i174-195o215-235i247- 265o277-298i310-334o430-448i); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0003975 - UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase activity [Evidence IEA]; go_function: GO:0008963 - phospho-N-acetylmuramoyl-pentapeptide-transferase activity [Evidence IEA]; go_process: GO:0006487 - protein N-linked glycosylation [Evidence IEA]; go_process: GO:0006488 - dolichol-linked oligosaccharide biosynthetic process [Evidence IEA] AKAW2_21347S COG:E; EggNog:ENOG410Q1C6; InterPro:IPR004841; PFAM:PF13520,PF00324; TransMembrane:11 (n2-13c20/21o30-50i80-101o107-124i136-159o179-205i233- 252o272-291i329-349o361-381i401-423o443-461i); go_component: GO:0016020 - membrane [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_21348S COG:E; EggNog:ENOG410PKXG; InterPro:IPR011011,IPR001214,IPR013083; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_21349S COG:S; EggNog:ENOG410PP0S; InterPro:IPR037401,IPR032710; PFAM:PF13577 AKAW2_21350S COG:S; EggNog:ENOG410PVXQ; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i46-67o87-109i121-141o147-166i178-197o209-227i247- 268o288-306i318-336o348-367i388-412o432-452i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_21351S BUSCO:EOG09263UWJ; COG:K; EggNog:ENOG410PK36; InterPro:IPR031336,IPR038103,IPR007852; PFAM:PF05179; go_component: GO:0016593 - Cdc73/Paf1 complex [Evidence IEA]; go_process: GO:0006368 - transcription elongation from RNA polymerase II promoter [Evidence IEA]; go_process: GO:0016570 - histone modification [Evidence IEA] AKAW2_21352A BUSCO:EOG092621F2; COG:T; EggNog:ENOG410PJRS; InterPro:IPR036305,IPR036388,IPR016137,IPR036390, IPR000591; PFAM:PF00615,PF00610; go_process: GO:0035556 - intracellular signal transduction [Evidence IEA] AKAW2_21354A BUSCO:EOG092630MJ; COG:L; EggNog:ENOG410PGV6; InterPro:IPR016527,IPR027417,IPR003593,IPR041664, IPR032705; PFAM:PF00004,PF13191,PF14629; go_component: GO:0000808 - origin recognition complex [Evidence IEA]; go_component: GO:0005634 - nucleus [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_process: GO:0006260 - DNA replication [Evidence IEA] AKAW2_21355S COG:S; EggNog:ENOG410PQMP; InterPro:IPR039298,IPR029069,IPR006683; PFAM:PF03061; go_function: GO:0047617 - acyl-CoA hydrolase activity [Evidence IEA] AKAW2_21356A BUSCO:EOG09262739; COG:O; EggNog:ENOG410PHJ6; InterPro:IPR018203,IPR036188,IPR000806; PFAM:PF00996; go_function: GO:0005092 - GDP-dissociation inhibitor activity [Evidence IEA]; go_function: GO:0005093 - Rab GDP-dissociation inhibitor activity [Evidence IEA]; go_process: GO:0007264 - small GTPase mediated signal transduction [Evidence IEA]; go_process: GO:0015031 - protein transport [Evidence IEA] AKAW2_21357A BUSCO:EOG09264BWL; COG:J; EggNog:ENOG410PJ4W; InterPro:IPR010729,IPR038340; PFAM:PF06984; go_component: GO:0005761 - mitochondrial ribosome [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_process: GO:0006412 - translation [Evidence IEA] AKAW2_21358S COG:D,K; EggNog:ENOG410PJGM; InterPro:IPR007282,IPR040168,IPR038635; PFAM:PF04153; go_component: GO:0030015 - CCR4-NOT core complex [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_21359A COG:S; EggNog:ENOG410PRAD; InterPro:IPR029063,IPR041698; PFAM:PF13649,PF13489,PF01209,PF08241 AKAW2_21360S COG:S; EggNog:ENOG410PJ72; InterPro:IPR000073,IPR029058; PFAM:PF12697; SECRETED:SignalP(1-20) AKAW2_21361S COG:D; EggNog:ENOG410PH55; InterPro:IPR010935,IPR003395,IPR027417,IPR036277, IPR027120,IPR024704; PFAM:PF06470,PF02463; go_component: GO:0005694 - chromosome [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0051276 - chromosome organization [Evidence IEA] AKAW2_21362S COG:O; EggNog:ENOG410PRQ0; InterPro:IPR003892; PFAM:PF02845; TransMembrane:1 (o6-28i); go_function: GO:0043130 - ubiquitin binding [Evidence IEA] AKAW2_21363A BUSCO:EOG09264QRY; COG:L; EggNog:ENOG410PNE1; InterPro:IPR036224,IPR021151,IPR007257; PFAM:PF05916; go_component: GO:0005634 - nucleus [Evidence IEA]; go_process: GO:0006260 - DNA replication [Evidence IEA] AKAW2_21364S BUSCO:EOG0926300R; CAZy:GT59; COG:G; EggNog:ENOG410PKSX; InterPro:IPR016900; PFAM:PF04922; TransMembrane:12 (i12-29o70-86i98-116o136-166i178-195o201-217i276-293o313- 337i360-385o405-428i505-525o576-594i); go_function: GO:0106073 - dolichyl pyrophosphate Glc2Man9GlcNAc2 alpha-1,2-glucosyltransferase activity [Evidence IEA]; go_process: GO:0006488 - dolichol-linked oligosaccharide biosynthetic process [Evidence IEA] AKAW2_21365S COG:L; EggNog:ENOG410PIHZ; InterPro:IPR027415,IPR010347; PFAM:PF06087; go_component: GO:0005634 - nucleus [Evidence IEA]; go_function: GO:0008081 - phosphoric diester hydrolase activity [Evidence IEA]; go_process: GO:0006281 - DNA repair [Evidence IEA] AKAW2_21366A COG:I; EggNog:ENOG410Q28P; InterPro:IPR014352,IPR035984,IPR000582; PFAM:PF00887; go_function: GO:0000062 - fatty-acyl-CoA binding [Evidence IEA] AKAW2_21367S COG:H; EggNog:ENOG410PHDH; InterPro:IPR036615,IPR036565,IPR001645,IPR018109, IPR013221,IPR023600; PFAM:PF08245; TransMembrane:1 (o480-498i); go_function: GO:0004326 - tetrahydrofolylpolyglutamate synthase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016874 - ligase activity [Evidence IEA]; go_process: GO:0009058 - biosynthetic process [Evidence IEA]; go_process: GO:0009396 - folic acid-containing compound biosynthetic process [Evidence IEA] AKAW2_21368A COG:O; EggNog:ENOG410PP5I; InterPro:IPR011990,IPR003613,IPR019734,IPR013026, IPR013083; PFAM:PF04564; go_function: GO:0004842 - ubiquitin-protein transferase activity [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0016567 - protein ubiquitination [Evidence IEA] AKAW2_21369A COG:G; EggNog:ENOG410PP11; InterPro:IPR003500,IPR011860,IPR036569; PFAM:PF02502; go_function: GO:0016853 - isomerase activity [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_21370S COG:G; EggNog:ENOG410PVEW; InterPro:IPR035990,IPR000652,IPR013785; PFAM:PF00121; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0004807 - triose-phosphate isomerase activity [Evidence IEA] AKAW2_21372A BUSCO:EOG092624RX; COG:F; EggNog:ENOG410PFTF; InterPro:IPR005720,IPR001295,IPR005719,IPR013785; PFAM:PF01180; TransMembrane:1 (i80-97o); go_component: GO:0005737 - cytoplasm [Evidence IEA]; go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0004152 - dihydroorotate dehydrogenase activity [Evidence IEA]; go_function: GO:0016627 - oxidoreductase activity, acting on the CH-CH group of donors [Evidence IEA]; go_process: GO:0006207 - 'de novo' pyrimidine nucleobase biosynthetic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_21373A BUSCO:EOG09264331; COG:K; EggNog:ENOG410PKD6; InterPro:IPR007133; PFAM:PF03985; go_component: GO:0016593 - Cdc73/Paf1 complex [Evidence IEA]; go_process: GO:0006368 - transcription elongation from RNA polymerase II promoter [Evidence IEA]; go_process: GO:0016570 - histone modification [Evidence IEA] AKAW2_21374A BUSCO:EOG0926248P; COG:Z; EggNog:ENOG410PKM7; InterPro:IPR043129,IPR004000,IPR027668; PFAM:PF00022; go_component: GO:0031011 - Ino80 complex [Evidence IEA]; go_process: GO:0006338 - chromatin remodeling [Evidence IEA] AKAW2_21375S COG:U; EggNog:ENOG410PKEM; InterPro:IPR005225,IPR027417,IPR006689; PFAM:PF00025,PF08477,PF00071,PF01926,PF09439; go_function: GO:0005525 - GTP binding [Evidence IEA] AKAW2_21376S COG:Q; EggNog:ENOG410Q2HF; InterPro:IPR013154,IPR013149,IPR036291,IPR011032, IPR020843; PFAM:PF00107,PF08240,PF13602; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_21377S COG:S; EggNog:ENOG410PQ16 AKAW2_21378A COG:S; EggNog:ENOG410PWV9 AKAW2_21379A COG:S; EggNog:ENOG410PWNQ AKAW2_21380S COG:I; EggNog:ENOG410PG8P; InterPro:IPR021829,IPR029063; PFAM:PF11899; TransMembrane:1 (o20-38i) AKAW2_21381A BUSCO:EOG09265ANI; COG:U; EggNog:ENOG410PM5F; InterPro:IPR004932; PFAM:PF03248; TransMembrane:4 (i37-56o62-79i123-141o147-165i); go_component: GO:0016021 - integral component of membrane [Evidence IEA] AKAW2_21382S COG:I; EggNog:ENOG410PHEJ; InterPro:IPR029045,IPR001753,IPR014748,IPR018376; PFAM:PF16113,PF00378; go_function: GO:0003824 - catalytic activity [Evidence IEA] AKAW2_21383A COG:G; EggNog:ENOG410PJ5K; InterPro:IPR005829,IPR005828,IPR003663,IPR036259, IPR020846; PFAM:PF00083,PF07690; TransMembrane:8 (i138-157o163-185i197-216o236-257i384-405o417-439i459- 476o482-503i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_21384S COG:S; EggNog:ENOG410PMBN; InterPro:IPR006598; TransMembrane:10 (n13-26c34/35o44-65i77-95o101-119i131-153o159-180i200- 221o227-244i251-270o276-292i304-325o) AKAW2_21385A COG:U; EggNog:ENOG410QE2K; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; SECRETED:SignalP(1-19); TransMembrane:13 (n2-13c21/22o37-53i65-84o90-112i124-149o155-173i194- 216o222-243i264-281o301-320i327-349o355-374i395-415o466- 484i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_21386S COG:S; EggNog:ENOG410Q2VF AKAW2_21387S COG:P; EggNog:ENOG410PHHM; InterPro:IPR018028,IPR011614,IPR024708,IPR002226, IPR020835,IPR024711,IPR037060,IPR010582; PFAM:PF00199,PF06628; go_function: GO:0004096 - catalase activity [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0006979 - response to oxidative stress [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_21388S COG:U; EggNog:ENOG410QDQ0; InterPro:IPR003123,IPR037191; PFAM:PF02204 AKAW2_21389A COG:S; EggNog:ENOG410PXM7; InterPro:IPR029178; PFAM:PF15463 AKAW2_21390A COG:S; EggNog:ENOG410PP50; InterPro:IPR007224; go_function: GO:0001164 - RNA polymerase I core promoter sequence-specific DNA binding [Evidence IEA]; go_function: GO:0001181 - RNA polymerase I general transcription initiation factor activity [Evidence IEA]; go_process: GO:0006361 - transcription initiation from RNA polymerase I promoter [Evidence IEA] AKAW2_21391S COG:O; EggNog:ENOG410PR2Z; InterPro:IPR001841,IPR011016,IPR013083; PFAM:PF17123,PF13923,PF00097,PF13639,PF12678; go_function: GO:0008270 - zinc ion binding [Evidence IEA] AKAW2_21392S BUSCO:EOG09264G7L; COG:F; EggNog:ENOG410PNSU; InterPro:IPR002376,IPR004607,IPR036477; PFAM:PF00551; go_function: GO:0004644 - phosphoribosylglycinamide formyltransferase activity [Evidence IEA]; go_function: GO:0016742 - hydroxymethyl-, formyl-and related transferase activity [Evidence IEA]; go_process: GO:0006189 - 'de novo' IMP biosynthetic process [Evidence IEA]; go_process: GO:0009058 - biosynthetic process [Evidence IEA] AKAW2_21394S COG:S; EggNog:ENOG410PJTJ; InterPro:IPR036864,IPR021858,IPR001138; PFAM:PF00172,PF11951; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_21393A BUSCO:EOG09260DXP; COG:A; EggNog:ENOG410PFZG; InterPro:IPR018973,IPR027417,IPR001650,IPR014001, IPR011545; PFAM:PF00270,PF00271,PF09369; TransMembrane:1 (o941-958i); go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA] AKAW2_21395S CAZy:GH76; COG:U; EggNog:ENOG410PYVP; InterPro:IPR014480,IPR008928,IPR005198; PFAM:PF03663; SECRETED:SignalP(1-21); TransMembrane:1 (n6-14c21/22o438-459i); go_function: GO:0008496 - mannan endo-1,6-alpha-mannosidase activity [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA]; go_process: GO:0016052 - carbohydrate catabolic process [Evidence IEA] AKAW2_21396A COG:U; EggNog:ENOG410Q16E; InterPro:IPR000156,IPR011993; PFAM:PF00638; go_process: GO:0046907 - intracellular transport [Evidence IEA] AKAW2_21397A COG:U; EggNog:ENOG410PMU1; InterPro:IPR006977; PFAM:PF04893; TransMembrane:5 (o170-188i195-218o224-245i257-279o285-303i); go_component: GO:0016020 - membrane [Evidence IEA] AKAW2_21398A COG:S; EggNog:ENOG410PGW5; InterPro:IPR002885,IPR011990; PFAM:PF13041; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_21399A COG:K; EggNog:ENOG410PN3N; InterPro:IPR039327,IPR013087; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_21400S CAZy:CE16; COG:S; EggNog:ENOG410PN2U; InterPro:IPR036514; SECRETED:SignalP(1-18) AKAW2_21401A COG:A; EggNog:ENOG410PGKN; InterPro:IPR027417,IPR001650,IPR014014,IPR014001, IPR011545,IPR000629; PFAM:PF00270,PF00271; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0004386 - helicase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA] AKAW2_21402A COG:H; EggNog:ENOG410PHBK; InterPro:IPR029056,IPR004305,IPR013749,IPR004399, IPR016084,IPR027574; PFAM:PF08543,PF03070; go_function: GO:0008972 - phosphomethylpyrimidine kinase activity [Evidence IEA]; go_function: GO:0050334 - thiaminase activity [Evidence IEA]; go_process: GO:0006772 - thiamine metabolic process [Evidence IEA]; go_process: GO:0009228 - thiamine biosynthetic process [Evidence IEA] AKAW2_21403A BUSCO:EOG09260375; COG:L; EggNog:ENOG410PFBM; InterPro:IPR043502,IPR024647,IPR006172,IPR038256, IPR036397,IPR012337,IPR017964,IPR006134,IPR006133, IPR023211,IPR015088,IPR042087; PFAM:PF03104,PF08996,PF12254,PF00136; go_function: GO:0000166 - nucleotide binding [Evidence IEA]; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0003887 - DNA-directed DNA polymerase activity [Evidence IEA]; go_process: GO:0006260 - DNA replication [Evidence IEA] AKAW2_21404A COG:S; EggNog:ENOG410PPUE; InterPro:IPR032675 AKAW2_21405S COG:D,L; EggNog:ENOG410PHQ5; InterPro:IPR026584,IPR007268; PFAM:PF02144,PF04139; go_component: GO:0030896 - checkpoint clamp complex [Evidence IEA]; go_process: GO:0000077 - DNA damage checkpoint [Evidence IEA]; go_process: GO:0006281 - DNA repair [Evidence IEA] AKAW2_21406A COG:P; EggNog:ENOG410PHDT; InterPro:IPR020846,IPR005828,IPR036259; TransMembrane:11 (o143-162i169-187o193-211i246-268o288-306i339-359o379- 403i415-434o446-467i479-501o507-525i); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_21407A COG:S; EggNog:ENOG410PUHW; InterPro:IPR029058 AKAW2_21411A BUSCO:EOG09260R9L; COG:A; EggNog:ENOG410PH9B; InterPro:IPR004087,IPR004088,IPR036612; PFAM:PF00013; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0003723 - RNA binding [Evidence IEA] AKAW2_21413A COG:S; EggNog:ENOG410PGX1 AKAW2_21415S COG:S; EggNog:ENOG410PJ6V; InterPro:IPR006439,IPR010237,IPR036412,IPR023214; PFAM:PF13419,PF00702; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_21416S COG:Z; EggNog:ENOG410QDSP; InterPro:IPR036859,IPR000938,IPR022157; PFAM:PF12455,PF01302; antiSMASH:Cluster_2.6 AKAW2_21417A CAZy:GT2_Chitin_synth; COG:M; EggNog:ENOG410PFHC; InterPro:IPR029044,IPR014876,IPR004835,IPR036037, IPR001609,IPR027417,IPR001199,IPR036400; PFAM:PF00173,PF00063,PF13641,PF03142,PF08766, PF13632; TransMembrane:6 (o896-912i933-955o1203-1225i1601-1622o1628-1649i1656- 1679o); antiSMASH:Cluster_2.6; go_component: GO:0016459 - myosin complex [Evidence IEA]; go_function: GO:0003774 - motor activity [Evidence IEA]; go_function: GO:0004100 - chitin synthase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016758 - transferase activity, transferring hexosyl groups [Evidence IEA] AKAW2_21418S CAZy:GT2_Chitin_synth; COG:M; EggNog:ENOG410PGZG; InterPro:IPR029044,IPR014876,IPR004835,IPR036961, IPR001609,IPR027417,IPR001199,IPR036400; PFAM:PF00173,PF13641,PF03142,PF08766,PF13632; TransMembrane:6 (o731-751i767-787o1028-1046i1419-1442o1454-1473i1480- 1503o); antiSMASH:Cluster_2.6; go_component: GO:0016459 - myosin complex [Evidence IEA]; go_function: GO:0003774 - motor activity [Evidence IEA]; go_function: GO:0004100 - chitin synthase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016758 - transferase activity, transferring hexosyl groups [Evidence IEA] AKAW2_21419S COG:S; EggNog:ENOG410PS1T; InterPro:IPR009395; PFAM:PF06320; antiSMASH:Cluster_2.6; go_component: GO:0031083 - BLOC-1 complex [Evidence IEA] AKAW2_21420A COG:I; EggNog:ENOG410PKUW; InterPro:IPR000873,IPR020845,IPR009081,IPR006162, IPR036736,IPR042099,IPR023213,IPR001242; PFAM:PF00501,PF00668,PF00550; SMCOG1002:AMP-dependent synthetase and ligase; antiSMASH:Cluster_2.6; go_function: GO:0003824 - catalytic activity [Evidence IEA] AKAW2_21421A COG:E; EggNog:ENOG410PVJI; InterPro:IPR015590,IPR005931,IPR016160,IPR016161, IPR016162,IPR016163; PFAM:PF00171; SMCOG1017:aldehyde dehydrogenase; antiSMASH:Cluster_2.6; go_function: GO:0003842 - 1-pyrroline-5-carboxylate dehydrogenase activity [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0016620 - oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Evidence IEA]; go_process: GO:0010133 - proline catabolic process to glutamate [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_21422A COG:L; EggNog:ENOG410PFR6; InterPro:IPR014790,IPR042121,IPR042120,IPR013507, IPR038973,IPR037198,IPR020568,IPR014721; PFAM:PF08676,PF01119; antiSMASH:Cluster_2.6; go_component: GO:0032300 - mismatch repair complex [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA]; go_function: GO:0030983 - mismatched DNA binding [Evidence IEA]; go_process: GO:0006298 - mismatch repair [Evidence IEA] AKAW2_21423A COG:S; EggNog:ENOG410PFX9; InterPro:IPR005016,IPR029559; PFAM:PF03348; SECRETED:SignalP(1-17); TransMembrane:9 (n4-15c33/34o49-71i92-117o137-157i164-185o205-227i239- 258o264-282i405-425o445-471i); go_component: GO:0016020 - membrane [Evidence IEA] AKAW2_21424S COG:S; EggNog:ENOG410PJUQ; InterPro:IPR010658,IPR036259; PFAM:PF07690,PF06813; TransMembrane:12 (i12-31o51-71i78-98o104-129i141-161o173-192i278-299o319- 336i357-377o383-406i418-439o465-484i) AKAW2_21425A COG:T; EggNog:ENOG410Q23Q; InterPro:IPR000719,IPR011009; PFAM:PF00069; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_21426A COG:K; EggNog:ENOG410PNK7; InterPro:IPR039355,IPR000679,IPR013088; PFAM:PF00320; go_function: GO:0003700 - DNA-binding transcription factor activity [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_function: GO:0043565 - sequence-specific DNA binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA]; go_process: GO:0006357 - regulation of transcription by RNA polymerase II [Evidence IEA] AKAW2_21427S COG:T; EggNog:ENOG410PFJI; InterPro:IPR018936,IPR039756,IPR000403; PFAM:PF00454; go_function: GO:0004430 - 1-phosphatidylinositol 4-kinase activity [Evidence IEA]; go_function: GO:0016301 - kinase activity [Evidence IEA] AKAW2_21428S COG:L; EggNog:ENOG410QDFP; InterPro:IPR001841,IPR038718,IPR000330,IPR027417, IPR001650,IPR014001; PFAM:PF00176,PF00270,PF00271; go_function: GO:0005524 - ATP binding [Evidence IEA] AKAW2_21429A BUSCO:EOG09265SHM; COG:K; EggNog:ENOG410PP4I; InterPro:IPR037212,IPR021384; PFAM:PF11221; go_component: GO:0016592 - mediator complex [Evidence IEA] AKAW2_21430S BUSCO:EOG09264YIJ; COG:S; EggNog:ENOG410PPRQ; InterPro:IPR018828; PFAM:PF04471 AKAW2_21431A COG:S; EggNog:ENOG410PMZZ; InterPro:IPR013252; PFAM:PF08286 AKAW2_21432S BUSCO:EOG09265A4E; COG:M; EggNog:ENOG410PMVK; InterPro:IPR011990,IPR028058,IPR033745,IPR016543, IPR028061; PFAM:PF14852,PF14853; TransMembrane:1 (o125-147i); go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0000266 - mitochondrial fission [Evidence IEA] AKAW2_21433S COG:O; EggNog:ENOG410PSEB; InterPro:IPR001841,IPR013083; PFAM:PF17123,PF13923,PF13920,PF00097,PF13445, PF13639,PF12678 AKAW2_21434A BUSCO:EOG09260XOG; COG:E; EggNog:ENOG410PFFQ; InterPro:IPR002028,IPR011060,IPR023026,IPR001926, IPR036052,IPR013785,IPR018204,IPR006654,IPR006653; PFAM:PF00291,PF00290; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0004834 - tryptophan synthase activity [Evidence IEA]; go_process: GO:0000162 - tryptophan biosynthetic process [Evidence IEA]; go_process: GO:0006568 - tryptophan metabolic process [Evidence IEA] AKAW2_21435A COG:K; EggNog:ENOG410PI13 AKAW2_21437A COG:S; EggNog:ENOG410Q2BC AKAW2_21438A COG:C; EggNog:ENOG410PHMT; InterPro:IPR013154,IPR013149,IPR036291,IPR011032, IPR020843; PFAM:PF00107,PF08240,PF13602; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_21439S COG:S; EggNog:ENOG410QE4N; InterPro:IPR035445,IPR003169; PFAM:PF02213; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_21440S COG:E; EggNog:ENOG410QDDF; InterPro:IPR000192,IPR015424,IPR015421; go_function: GO:0003824 - catalytic activity [Evidence IEA] AKAW2_21441A BUSCO:EOG09261KHB; COG:C; EggNog:ENOG410PI53; InterPro:IPR022879,IPR027417,IPR005723,IPR004100, IPR020003,IPR000194; PFAM:PF00006,PF02874; go_component: GO:0033180 - proton-transporting V-type ATPase, V1 domain [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0046034 - ATP metabolic process [Evidence IEA]; go_process: GO:1902600 - proton transmembrane transport [Evidence IEA] AKAW2_21442S COG:J; EggNog:ENOG410PFD6; InterPro:IPR002305,IPR023617,IPR002307,IPR014729; PFAM:PF00579; go_function: GO:0000166 - nucleotide binding [Evidence IEA]; go_function: GO:0004812 - aminoacyl-tRNA ligase activity [Evidence IEA]; go_function: GO:0004831 - tyrosine-tRNA ligase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006418 - tRNA aminoacylation for protein translation [Evidence IEA]; go_process: GO:0006437 - tyrosyl-tRNA aminoacylation [Evidence IEA] AKAW2_21443A COG:T; EggNog:ENOG410PFZ0; InterPro:IPR006015,IPR006016; PFAM:PF00582 AKAW2_21444A COG:O; EggNog:ENOG410PKFU; InterPro:IPR001623,IPR036869,IPR018253; PFAM:PF00226 AKAW2_21446S COG:F; EggNog:ENOG410QEB2; InterPro:IPR002125,IPR016193; PFAM:PF08210,PF00383,PF18785; go_function: GO:0003824 - catalytic activity [Evidence IEA] AKAW2_21445A COG:J; EggNog:ENOG410PFWE; InterPro:IPR020568,IPR001247; PFAM:PF01138 AKAW2_21447A BUSCO:EOG09261EU7; COG:T; EggNog:ENOG410PHI0; InterPro:IPR017441,IPR008271,IPR000719,IPR011009; PFAM:PF07714,PF00069; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_21449S COG:S; EggNog:ENOG410PTMK; InterPro:IPR024630,IPR043069; PFAM:PF12898 AKAW2_21450S COG:S; EggNog:ENOG410PQ2D AKAW2_21451A COG:S; EggNog:ENOG410PX1K; InterPro:IPR012340,IPR040260 AKAW2_21452A COG:T; EggNog:ENOG410PN2S; InterPro:IPR004307,IPR038330; PFAM:PF03073; TransMembrane:5 (o12-31i51-73o106-124i131-149o161-184i); go_component: GO:0016021 - integral component of membrane [Evidence IEA] AKAW2_21453A COG:S; EggNog:ENOG410PQDX; TransMembrane:1 (i119-137o) AKAW2_21454S COG:C; EggNog:ENOG410PPQA; InterPro:IPR002327,IPR009056,IPR036909; PFAM:PF00034,PF13442; go_function: GO:0009055 - electron transfer activity [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA] AKAW2_21455S COG:S; EggNog:ENOG410PMPR; TransMembrane:1 (i217-236o) AKAW2_21456A BUSCO:EOG09263PXH; COG:K; EggNog:ENOG410PG4T; InterPro:IPR036603,IPR001514,IPR011262,IPR011263, IPR036643; PFAM:PF01193,PF01000; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0003899 - DNA-directed 5'-3' RNA polymerase activity [Evidence IEA]; go_function: GO:0046983 - protein dimerization activity [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA] AKAW2_21457A BUSCO:EOG09265BJ3; COG:T; EggNog:ENOG410PPGG; InterPro:IPR015797,IPR000086; PFAM:PF00293; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_21458S BUSCO:EOG092638AP; COG:O; EggNog:ENOG410PI52; InterPro:IPR007471,IPR007472,IPR016181,IPR030700, IPR017137; PFAM:PF04377,PF04376; go_function: GO:0004057 - arginyltransferase activity [Evidence IEA]; go_process: GO:0016598 - protein arginylation [Evidence IEA] AKAW2_21459S BUSCO:EOG09264IDN; COG:O; EggNog:ENOG410PMR5; InterPro:IPR013805,IPR009012,IPR000740; PFAM:PF01025; go_function: GO:0000774 - adenyl-nucleotide exchange factor activity [Evidence IEA]; go_function: GO:0042803 - protein homodimerization activity [Evidence IEA]; go_function: GO:0051087 - chaperone binding [Evidence IEA]; go_process: GO:0006457 - protein folding [Evidence IEA] AKAW2_21460S BUSCO:EOG09262N0U; COG:J; EggNog:ENOG410PFED; InterPro:IPR006195,IPR005121,IPR004530,IPR002319, IPR036690; PFAM:PF01409,PF03147; go_component: GO:0005737 - cytoplasm [Evidence IEA]; go_function: GO:0000049 - tRNA binding [Evidence IEA]; go_function: GO:0000166 - nucleotide binding [Evidence IEA]; go_function: GO:0004812 - aminoacyl-tRNA ligase activity [Evidence IEA]; go_function: GO:0004826 - phenylalanine-tRNA ligase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006432 - phenylalanyl-tRNA aminoacylation [Evidence IEA]; go_process: GO:0043039 - tRNA aminoacylation [Evidence IEA] AKAW2_21461S COG:C; EggNog:ENOG410PGRA; InterPro:IPR018108,IPR023395,IPR002030; go_component: GO:0031966 - mitochondrial membrane [Evidence IEA]; go_process: GO:0006839 - mitochondrial transport [Evidence IEA] AKAW2_21462A BUSCO:EOG09265JVH; COG:C; EggNog:ENOG410PRAX; InterPro:IPR003213,IPR036549; PFAM:PF02297; go_component: GO:0005739 - mitochondrion [Evidence IEA]; go_component: GO:0045277 - respiratory chain complex IV [Evidence IEA] AKAW2_21463S COG:S; EggNog:ENOG410PSKY; InterPro:IPR010530; TransMembrane:1 (o43-62i) AKAW2_21464A COG:O; EggNog:ENOG410PNQ9; InterPro:IPR000504,IPR012677,IPR034168,IPR035979; PFAM:PF00076; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0003723 - RNA binding [Evidence IEA] AKAW2_21465S BUSCO:EOG09260A98; COG:U; EggNog:ENOG410QDCP; InterPro:IPR040251,IPR036322,IPR015943,IPR001680, IPR009917,IPR024298,IPR017986; PFAM:PF00400,PF07304,PF12931; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0006888 - endoplasmic reticulum to Golgi vesicle-mediated transport [Evidence IEA] AKAW2_21466A COG:S; EggNog:ENOG410PN4Q; InterPro:IPR006785,IPR025655,IPR036388; PFAM:PF04695; go_component: GO:0005778 - peroxisomal membrane [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0016560 - protein import into peroxisome matrix, docking [Evidence IEA] AKAW2_21467S COG:S; EggNog:ENOG410PQJT; InterPro:IPR029523,IPR006880; PFAM:PF04795; go_component: GO:0031011 - Ino80 complex [Evidence IEA]; go_process: GO:0006338 - chromatin remodeling [Evidence IEA] AKAW2_21468A TransMembrane:1 (o6-23i) AKAW2_21469S COG:S; EggNog:ENOG410PH19; InterPro:IPR019021; PFAM:PF09462; go_component: GO:0005634 - nucleus [Evidence IEA]; go_process: GO:0006281 - DNA repair [Evidence IEA]; go_process: GO:0006974 - cellular response to DNA damage stimulus [Evidence IEA]; go_process: GO:0031297 - replication fork processing [Evidence IEA] AKAW2_21470A COG:S; EggNog:ENOG410PSZ6; InterPro:IPR025124; PFAM:PF13259 AKAW2_21471A COG:O; EggNog:ENOG410PFZ9; InterPro:IPR041569,IPR003959,IPR027417,IPR003593; PFAM:PF00004,PF17862; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA] AKAW2_21472S COG:S; EggNog:ENOG410PNXR; InterPro:IPR029005; PFAM:PF01803 AKAW2_21473S COG:K,O; EggNog:ENOG410PK35; InterPro:IPR004400,IPR027417,IPR003495; PFAM:PF02492; go_function: GO:0003924 - GTPase activity [Evidence IEA]; go_function: GO:0016151 - nickel cation binding [Evidence IEA]; go_process: GO:0006807 - nitrogen compound metabolic process [Evidence IEA] AKAW2_21474A BUSCO:EOG09261UMG; COG:A; EggNog:ENOG410PHNQ; InterPro:IPR036322,IPR015943,IPR040315,IPR019775, IPR001680,IPR012952,IPR017986; PFAM:PF08149; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_21475S BUSCO:EOG092615SM; COG:S; EggNog:ENOG410PGXY; InterPro:IPR039761,IPR030387,IPR007034,IPR012948; PFAM:PF08142,PF04950; go_component: GO:0005634 - nucleus [Evidence IEA]; go_process: GO:0042254 - ribosome biogenesis [Evidence IEA] AKAW2_21476A BUSCO:EOG09263X22; COG:U; EggNog:ENOG410PH2H; InterPro:IPR011990,IPR000744; PFAM:PF14938; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0006886 - intracellular protein transport [Evidence IEA] AKAW2_21477S COG:S; EggNog:ENOG410PR7H; InterPro:IPR036113,IPR003837; PFAM:PF02686; go_process: GO:0006450 - regulation of translational fidelity [Evidence IEA] AKAW2_21478S COG:S; EggNog:ENOG410PJ9K; InterPro:IPR007941,IPR029058; PFAM:PF05277; TransMembrane:4 (i197-214o220-237i272-295o315-335i) AKAW2_21479A COG:S; EggNog:ENOG410Q2PA; InterPro:IPR022596,IPR023041; PFAM:PF11710,PF11970; TransMembrane:7 (n2-13c21/22o37-61i82-104o129-146i153-173o206-227i248- 265o285-307i) AKAW2_21480S COG:S; EggNog:ENOG410PQ64; InterPro:IPR010829,IPR036908; PFAM:PF07249; SECRETED:SignalP(1-19) AKAW2_21481A BUSCO:EOG09261UOJ; COG:C; EggNog:ENOG410PIFP; InterPro:IPR023753,IPR021163,IPR036188; PFAM:PF07992; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_21482S COG:S; EggNog:ENOG410PVB1; TransMembrane:4 (i90-110o116-140i152-177o206-230i) AKAW2_21483A COG:U; EggNog:ENOG410PN32; InterPro:IPR016187; TransMembrane:1 (o568-592i) AKAW2_21484S BUSCO:EOG09263W7L; COG:U; EggNog:ENOG410PGTC; InterPro:IPR004728,IPR011553; PFAM:PF03839; TransMembrane:3 (i260-279o285-303i308-325o); go_component: GO:0030176 - integral component of endoplasmic reticulum membrane [Evidence IEA]; go_process: GO:0015031 - protein transport [Evidence IEA] AKAW2_21485A COG:S; EggNog:ENOG410PKVR AKAW2_21486A COG:S; EggNog:ENOG410PYV0; InterPro:IPR001533,IPR036428; PFAM:PF01329; go_function: GO:0008124 - 4-alpha-hydroxytetrahydrobiopterin dehydratase activity [Evidence IEA]; go_process: GO:0006729 - tetrahydrobiopterin biosynthetic process [Evidence IEA] AKAW2_21487A COG:G; EggNog:ENOG410QDYM; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i89-105o125-145i157-174o186-206i213-240o246-265i323- 342o362-382i403-425o431-452i473-490o502-523i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_21488S COG:S; EggNog:ENOG410PY98 AKAW2_21490A COG:S; EggNog:ENOG410PN20; InterPro:IPR036291,IPR001509; PFAM:PF01370; go_function: GO:0003824 - catalytic activity [Evidence IEA] AKAW2_21491S COG:O; EggNog:ENOG410PI2R; InterPro:IPR038765,IPR035927,IPR001394,IPR018200, IPR006615,IPR028889; MEROPS:MER0005433; PFAM:PF06337,PF00443; go_function: GO:0004843 - thiol-dependent ubiquitin-specific protease activity [Evidence IEA]; go_process: GO:0006511 - ubiquitin-dependent protein catabolic process [Evidence IEA]; go_process: GO:0016579 - protein deubiquitination [Evidence IEA] AKAW2_21493A CAZy:GH43; COG:G; EggNog:ENOG410Q19N; InterPro:IPR023296,IPR006710; TransMembrane:1 (i38-55o); go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_21494A COG:U; EggNog:ENOG410PH48; InterPro:IPR001683,IPR027267,IPR036871,IPR044106; PFAM:PF00787; go_function: GO:0035091 - phosphatidylinositol binding [Evidence IEA]; go_process: GO:0042147 - retrograde transport, endosome to Golgi [Evidence IEA] AKAW2_21495A TransMembrane:1 (o6-29i) AKAW2_21496A BUSCO:EOG09260OZU; COG:D; EggNog:ENOG410PIB4; InterPro:IPR019442,IPR016024; PFAM:PF10350 AKAW2_21497S BUSCO:EOG09264NC7; COG:U; EggNog:ENOG410PGJA; PFAM:PF02466; TransMembrane:1 (i179-197o) AKAW2_21498A COG:M; EggNog:ENOG410PG00; InterPro:IPR002110,IPR036770,IPR001810,IPR020683; PFAM:PF12796,PF00023,PF13637; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_21499S COG:S; EggNog:ENOG410PT7R AKAW2_21500A COG:C; EggNog:ENOG410Q2DB; InterPro:IPR044152,IPR001155,IPR013785; PFAM:PF00724; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0003959 - NADPH dehydrogenase activity [Evidence IEA]; go_function: GO:0010181 - FMN binding [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0050661 - NADP binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_21501A COG:S; EggNog:ENOG410PTEQ AKAW2_21502S COG:S; EggNog:ENOG410PX1B; InterPro:IPR000868,IPR036380; PFAM:PF00857; SECRETED:SignalP(1-18) AKAW2_21503S COG:T; EggNog:ENOG410PFW7; InterPro:IPR000719,IPR011009,IPR008271; PFAM:PF07714,PF00069; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_21504S COG:G; EggNog:ENOG410PNE5; InterPro:IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i48-68o117-136i148-167o179-199i211-233o239-259i348- 372o392-410i422-439o445-467i479-505o511-534i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_21506S COG:I; EggNog:ENOG410PHRX; TransMembrane:2 (o30-55i67-85o) AKAW2_21505A COG:S; EggNog:ENOG410PPKR; InterPro:IPR010730; PFAM:PF06985 AKAW2_21507S COG:S; EggNog:ENOG410PR4T AKAW2_21508S COG:S; EggNog:ENOG410PHY3; InterPro:IPR019384; PFAM:PF10257 AKAW2_21509A COG:K; EggNog:ENOG410PRRH; InterPro:IPR009072,IPR027116,IPR003958; PFAM:PF00808; go_function: GO:0003712 - transcription coregulator activity [Evidence IEA]; go_function: GO:0046982 - protein heterodimerization activity [Evidence IEA] AKAW2_21511S COG:S; EggNog:ENOG410PVAR; InterPro:IPR033489,IPR013083; go_function: GO:0061630 - ubiquitin protein ligase activity [Evidence IEA]; go_process: GO:0006397 - mRNA processing [Evidence IEA]; go_process: GO:0016567 - protein ubiquitination [Evidence IEA] AKAW2_21512A BUSCO:EOG092627F1; COG:Z; EggNog:ENOG410PHD5; InterPro:IPR015505,IPR036322,IPR015943,IPR001680, IPR019775,IPR020472,IPR015048,IPR017986; PFAM:PF16300,PF00400,PF08953; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_21513S COG:Z; EggNog:ENOG410PGD5; InterPro:IPR036961,IPR027417,IPR001752,IPR019821; PFAM:PF00225,PF16796; go_function: GO:0003777 - microtubule motor activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0008017 - microtubule binding [Evidence IEA]; go_process: GO:0007018 - microtubule-based movement [Evidence IEA] AKAW2_21514S COG:I; EggNog:ENOG410PHHB; InterPro:IPR036938,IPR043216,IPR000326; PFAM:PF01569; TransMembrane:6 (i26-47o72-95i107-128o196-218i239-263o275-296i); go_function: GO:0008195 - phosphatidate phosphatase activity [Evidence IEA]; go_process: GO:0006644 - phospholipid metabolic process [Evidence IEA] AKAW2_21515A COG:S; EggNog:ENOG410PV22; InterPro:IPR021838; PFAM:PF11913; SECRETED:SignalP(1-24) AKAW2_21516S COG:S; EggNog:ENOG410Q1MH; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_21517A COG:S; EggNog:ENOG410Q2IB AKAW2_21518S COG:C,H; EggNog:ENOG410PIWS; InterPro:IPR036188,IPR002938; PFAM:PF01494; go_function: GO:0071949 - FAD binding [Evidence IEA] AKAW2_21519A COG:S; EggNog:ENOG410PJ5S AKAW2_21520A COG:S; EggNog:ENOG410PVJR; InterPro:IPR008979,IPR029058,IPR005674,IPR013736, IPR000383; PFAM:PF02129,PF08530; go_function: GO:0008239 - dipeptidyl-peptidase activity [Evidence IEA]; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_21522S COG:E; EggNog:ENOG410PISA; InterPro:IPR002933,IPR011650,IPR017439,IPR036264; MEROPS:MER0002007; PFAM:PF01546,PF07687; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_21521A COG:J; EggNog:ENOG410PMTS; InterPro:IPR042529,IPR000086,IPR000649,IPR015797, IPR037171; PFAM:PF00293,PF01008; go_function: GO:0016787 - hydrolase activity [Evidence IEA]; go_process: GO:0044237 - cellular metabolic process [Evidence IEA] AKAW2_21523S COG:S; EggNog:ENOG410PNTF; InterPro:IPR011057,IPR006913; PFAM:PF04828; go_function: GO:0016846 - carbon-sulfur lyase activity [Evidence IEA] AKAW2_21524A COG:F,H; EggNog:ENOG410PIAB; InterPro:IPR006083,IPR027417,IPR003593; PFAM:PF00485; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016301 - kinase activity [Evidence IEA] AKAW2_21525A COG:K; EggNog:ENOG410Q2Q5; InterPro:IPR036864; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_21526A SECRETED:SignalP(1-27) AKAW2_21527A COG:S; EggNog:ENOG410PQFT AKAW2_21528S antiSMASH:Cluster_2.7 AKAW2_21530S antiSMASH:Cluster_2.7 AKAW2_21529A COG:S; EggNog:ENOG410PWHY; InterPro:IPR036291,IPR008030; PFAM:PF13460,PF05368; antiSMASH:Cluster_2.7 AKAW2_21531S BUSCO:EOG09262B1U; COG:E; EggNog:ENOG410PFY6; InterPro:IPR000192,IPR015424,IPR022278,IPR015422; antiSMASH:Cluster_2.7; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0004648 - O-phospho-L-serine:2-oxoglutarate aminotransferase activity [Evidence IEA]; go_process: GO:0006564 - L-serine biosynthetic process [Evidence IEA] AKAW2_21532S COG:S; EggNog:ENOG410PVKA; InterPro:IPR027796,IPR002893; PFAM:PF14441,PF01753; antiSMASH:Cluster_2.7 AKAW2_21533S COG:L; EggNog:ENOG410Q1CR; antiSMASH:Cluster_2.7 AKAW2_21534S antiSMASH:Cluster_2.7 AKAW2_21535S CAZy:GH16; COG:G; EggNog:ENOG410Q2EI; InterPro:IPR000757,IPR013320; SECRETED:SignalP(1-24); antiSMASH:Cluster_2.7; go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_21536A COG:I; EggNog:ENOG410QE59; InterPro:IPR000873,IPR009081,IPR036736,IPR036291, IPR013120,IPR042099,IPR020845; PFAM:PF00501,PF00550,PF01370,PF07993; SMCOG1002:AMP-dependent synthetase and ligase; antiSMASH:Cluster_2.7 AKAW2_21537S COG:S; EggNog:ENOG410Q2NV; InterPro:IPR036390,IPR036388; antiSMASH:Cluster_2.7 AKAW2_21538S COG:S; EggNog:ENOG410Q2NV; InterPro:IPR029063,IPR016461,IPR001077; PFAM:PF00891; SMCOG1042:O-methyltransferase; antiSMASH:Cluster_2.7; go_function: GO:0008168 - methyltransferase activity [Evidence IEA]; go_function: GO:0008171 - O-methyltransferase activity [Evidence IEA] AKAW2_21539A antiSMASH:Cluster_2.7 AKAW2_21540S antiSMASH:Cluster_2.7 AKAW2_21541S COG:S; EggNog:ENOG410Q2I3; InterPro:IPR029058,IPR018712; PFAM:PF09994; antiSMASH:Cluster_2.7 AKAW2_21542S COG:G; EggNog:ENOG410PV9J; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; SMCOG1005:Drug resistance transporter, EmrB/QacA; TransMembrane:11 (o84-102i114-133o139-160i172-194o200-222i271-288o308- 330i351-370o382-404i451-471o491-510i); antiSMASH:Cluster_2.7; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_21543S COG:S; EggNog:ENOG410PNU0; TransMembrane:7 (o30-51i63-84o104-131i143-172o184-208i220-247o259-279i); antiSMASH:Cluster_2.7 AKAW2_21544S CAZy:AA7; COG:C; EggNog:ENOG410PMTA; InterPro:IPR016166,IPR006094,IPR036318; PFAM:PF01565; SECRETED:SignalP(1-17); go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_function: GO:0071949 - FAD binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_21545A CAZy:CE5; COG:S; EggNog:ENOG410PPRU; InterPro:IPR043580,IPR029058,IPR000675; PFAM:PF01083; SECRETED:SignalP(1-15); go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_21546A COG:S; EggNog:ENOG410PJ95; InterPro:IPR043129 AKAW2_21548A COG:S; EggNog:ENOG410PJ95; InterPro:IPR043129 AKAW2_21552A TransMembrane:1 (i84-103o) AKAW2_21553A COG:G; EggNog:ENOG410PITC; InterPro:IPR003710,IPR013752,IPR036291,IPR013332, IPR008927,IPR013328; PFAM:PF02558,PF08546; TransMembrane:1 (i7-24o); go_function: GO:0008677 - 2-dehydropantoate 2-reductase activity [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0015940 - pantothenate biosynthetic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_21554A COG:S; EggNog:ENOG410PIN4; InterPro:IPR021840; PFAM:PF11915; TransMembrane:8 (i75-97o117-138i184-203o561-591i683-706o726-746i796- 818o1143-1163i) AKAW2_21556S CAZy:GH2; COG:G; EggNog:ENOG410PJ3U; InterPro:IPR006103,IPR017853,IPR006104,IPR036156, IPR008979,IPR006102,IPR013783; PFAM:PF02837,PF00703; SECRETED:SignalP(1-17); go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_21557S COG:G; EggNog:ENOG410PJ41; InterPro:IPR005829,IPR005828,IPR003663,IPR036259, IPR020846; PFAM:PF00083,PF07690; TransMembrane:9 (o6-24i94-116o122-139i151-171o191-210i279-300o320-336i343- 365o458-476i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_21558S COG:T; EggNog:ENOG410PV7H; InterPro:IPR036457,IPR001932,IPR015655; PFAM:PF00481; go_function: GO:0004722 - protein serine/threonine phosphatase activity [Evidence IEA]; go_function: GO:0016791 - phosphatase activity [Evidence IEA]; go_process: GO:0006470 - protein dephosphorylation [Evidence IEA] AKAW2_21559A COG:F,Q; EggNog:ENOG410PM13; InterPro:IPR011059,IPR006680,IPR032466; MEROPS:MER0037714; PFAM:PF01979; go_function: GO:0016787 - hydrolase activity [Evidence IEA]; go_function: GO:0016810 - hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [Evidence IEA] AKAW2_21560S COG:P; EggNog:ENOG410PFK4; InterPro:IPR006042,IPR006043; PFAM:PF00860; TransMembrane:12 (i78-97o117-137i144-165o191-213i220-239o277-295i302- 322o334-358i429-451o463-482i489-507o527-549i); go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_21561A COG:Q; EggNog:ENOG410PHSI; InterPro:IPR026992,IPR027443,IPR005123; PFAM:PF03171,PF14226; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_21562S COG:S; EggNog:ENOG410PIJQ; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_21563A COG:S; EggNog:ENOG410PJPK; InterPro:IPR007568; PFAM:PF04479; TransMembrane:7 (n3-11c16/17o40-63i75-96o108-128i149-167o187-209i244- 262o282-302i); go_component: GO:0016021 - integral component of membrane [Evidence IEA] AKAW2_21564A SECRETED:SignalP(1-18) AKAW2_21565A COG:S; EggNog:ENOG410Q2TP; InterPro:IPR008253; PFAM:PF01284; TransMembrane:4 (o12-35i42-64o76-100i120-146o); go_component: GO:0016020 - membrane [Evidence IEA] AKAW2_21566A COG:S; EggNog:ENOG410Q23F AKAW2_21567A COG:B; EggNog:ENOG410PGXE; InterPro:IPR011990,IPR001214,IPR019734,IPR013026; PFAM:PF00856; antiSMASH:Cluster_2.8; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_21568A COG:S; EggNog:ENOG410PXTK; TransMembrane:6 (i12-34o54-75i96-116o122-148i169-192o204-225i); antiSMASH:Cluster_2.8 AKAW2_21569S CAZy:AA7; COG:S; EggNog:ENOG410PK2Z; InterPro:IPR006094,IPR036318,IPR016166,IPR012951; PFAM:PF08031,PF01565; SECRETED:SignalP(1-23); SMCOG1138:FAD linked oxidase domain protein; antiSMASH:Cluster_2.8; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_function: GO:0071949 - FAD binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_21570A COG:Q; EggNog:ENOG410PJA1; InterPro:IPR016036,IPR016035,IPR016039,IPR018201, IPR042104,IPR014030,IPR011032,IPR013968,IPR001227, IPR032821,IPR014031,IPR006162,IPR014043,IPR020806, IPR020807,IPR020843,IPR020841,IPR009081,IPR029063, IPR036736,IPR036291,IPR013217; PFAM:PF16197,PF00109,PF08659,PF00550,PF13489, PF13649,PF01209,PF02801,PF00698,PF13847,PF13602,PF14765, PF00107,PF00106,PF08242,PF08241; SMCOG1093:Beta-ketoacyl synthase; antiSMASH:Cluster_2.8; go_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein] synthase activity [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0016740 - transferase activity [Evidence IEA]; go_function: GO:0016746 - transferase activity, transferring acyl groups [Evidence IEA]; go_function: GO:0031177 - phosphopantetheine binding [Evidence IEA]; go_process: GO:0006633 - fatty acid biosynthetic process [Evidence IEA] AKAW2_21571S COG:S; EggNog:ENOG410PYGQ; InterPro:IPR005645,IPR029058; PFAM:PF03959; TransMembrane:1 (o81-99i); antiSMASH:Cluster_2.8 AKAW2_21572S COG:G; EggNog:ENOG410PH0T; InterPro:IPR011701,IPR036259; SMCOG1005:Drug resistance transporter, EmrB/QacA; TransMembrane:10 (i7-28o40-60i92-110o122-143i164-184o204-223i230-251o263- 290i302-321o366-386i); antiSMASH:Cluster_2.8; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_21573A CAZy:AA3; COG:E; EggNog:ENOG410PFGF; InterPro:IPR012132,IPR036188,IPR000172,IPR007867; PFAM:PF05199,PF00732; antiSMASH:Cluster_2.8; go_function: GO:0016614 - oxidoreductase activity, acting on CH-OH group of donors [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_21574S COG:S; EggNog:ENOG410PV5Q; TransMembrane:7 (o42-62i74-94o114-139i151-174o194-218i230-252o264-285i); antiSMASH:Cluster_2.8 AKAW2_21575S COG:S; EggNog:ENOG410PVBU; InterPro:IPR001810,IPR036047; antiSMASH:Cluster_2.8; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_21576S COG:O; EggNog:ENOG410PU84; InterPro:IPR011118,IPR029058; PFAM:PF07519; SECRETED:SignalP(1-19); antiSMASH:Cluster_2.8 AKAW2_21577A COG:I,J,T; EggNog:ENOG410PH99; InterPro:IPR023631,IPR036928,IPR020556; PFAM:PF01425; SMCOG1105:amidase; antiSMASH:Cluster_2.8 AKAW2_21578A COG:S; EggNog:ENOG410PW0E; SECRETED:SignalP(1-21); antiSMASH:Cluster_2.9 AKAW2_21579S COG:S; EggNog:ENOG410PY5J; antiSMASH:Cluster_2.9 AKAW2_21580S COG:K; EggNog:ENOG410PMT0; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; TransMembrane:4 (o235-253i280-305o311-329i350-367o); antiSMASH:Cluster_2.9; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_21581S COG:F; EggNog:ENOG410PFNK; InterPro:IPR011343,IPR028581,IPR002915,IPR013785; PFAM:PF01791; antiSMASH:Cluster_2.9; go_component: GO:0005737 - cytoplasm [Evidence IEA]; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0004139 - deoxyribose-phosphate aldolase activity [Evidence IEA]; go_function: GO:0016829 - lyase activity [Evidence IEA]; go_process: GO:0009264 - deoxyribonucleotide catabolic process [Evidence IEA] AKAW2_21582S COG:Q; EggNog:ENOG410PWJA; InterPro:IPR008775; PFAM:PF05721; antiSMASH:Cluster_2.9 AKAW2_21583S antiSMASH:Cluster_2.9 AKAW2_21584A COG:Q; EggNog:ENOG410PK2R; InterPro:IPR000873,IPR009081,IPR006162,IPR036291, IPR036736,IPR010080,IPR002347,IPR013120,IPR042099, IPR020845; PFAM:PF00501,PF00106,PF13561,PF00550,PF08659, PF01370,PF07993; SMCOG1002:AMP-dependent synthetase and ligase; antiSMASH:Cluster_2.9; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_21585A COG:S; EggNog:ENOG410PMJW; TransMembrane:7 (o36-55i67-88o116-137i149-171o205-225i237-261o281-300i); antiSMASH:Cluster_2.9 AKAW2_21586S COG:J; EggNog:ENOG410PGSJ; InterPro:IPR023631,IPR036928; PFAM:PF01425; SECRETED:SignalP(1-19); SMCOG1105:amidase; antiSMASH:Cluster_2.9 AKAW2_21587S COG:P; EggNog:ENOG410PFVH; InterPro:IPR001204; PFAM:PF01384; TransMembrane:9 (i48-67o87-105i117-136o148-177i184-206o218-244i256- 273o489-508i577-601o); antiSMASH:Cluster_2.9; go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0005315 - inorganic phosphate transmembrane transporter activity [Evidence IEA]; go_process: GO:0006817 - phosphate ion transport [Evidence IEA] AKAW2_21588S COG:E; EggNog:ENOG410PGKT; InterPro:IPR002821,IPR008040,IPR010318,IPR043129, IPR027479; PFAM:PF01968,PF05378,PF06032; antiSMASH:Cluster_2.9; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_21589A COG:S; EggNog:ENOG410Q2K9; antiSMASH:Cluster_2.9 AKAW2_21590A COG:S; EggNog:ENOG410Q2K9; TransMembrane:6 (o24-43i55-76o96-120i132-163o175-194i206-223o); antiSMASH:Cluster_2.9 AKAW2_21591S COG:Q; EggNog:ENOG410PMNM; InterPro:IPR001128,IPR002401,IPR036396; PFAM:PF00067; SMCOG1034:cytochrome P450; TransMembrane:1 (o23-43i); antiSMASH:Cluster_2.9; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_21592S CAZy:GH43; COG:G; EggNog:ENOG410PKCB; InterPro:IPR023296,IPR006710,IPR041542,IPR013320; PFAM:PF17851,PF04616; antiSMASH:Cluster_2.9; go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_21593A COG:S; EggNog:ENOG410PTTP; SECRETED:SignalP(1-18); antiSMASH:Cluster_2.9 AKAW2_21594A COG:S; EggNog:ENOG410PUNR; SECRETED:SignalP(1-18) AKAW2_21595A COG:S; EggNog:ENOG410PN0R; InterPro:IPR000073,IPR029058; PFAM:PF12697 AKAW2_21596A COG:Q; EggNog:ENOG410PI1I; InterPro:IPR011059,IPR006680,IPR032466; MEROPS:MER0005900; PFAM:PF01979; go_function: GO:0016787 - hydrolase activity [Evidence IEA]; go_function: GO:0016810 - hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [Evidence IEA] AKAW2_21597S COG:Q; EggNog:ENOG410PJRY; InterPro:IPR014185,IPR011057,IPR006913; PFAM:PF04828; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_function: GO:0016846 - carbon-sulfur lyase activity [Evidence IEA]; go_function: GO:0051907 - S-(hydroxymethyl)glutathione synthase activity [Evidence IEA]; go_process: GO:0046294 - formaldehyde catabolic process [Evidence IEA] AKAW2_21598A CAZy:CE10; COG:I; EggNog:ENOG410PNHB; InterPro:IPR033140,IPR029058,IPR013094; PFAM:PF07859; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_21599A COG:G; EggNog:ENOG410PVSU; InterPro:IPR005829,IPR005828,IPR003663,IPR036259, IPR020846; PFAM:PF00083,PF07690; TransMembrane:12 (i9-29o49-71i83-101o107-129i138-157o169-192i260-278o298- 319i326-347o353-372i392-411o423-441i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_21600A COG:S; EggNog:ENOG410PRI2; InterPro:IPR011008,IPR013097; PFAM:PF07876 AKAW2_21601S COG:S; EggNog:ENOG410PSRP AKAW2_21602A COG:I; EggNog:ENOG410PW2M; InterPro:IPR002018,IPR029058 AKAW2_21603A COG:G; EggNog:ENOG410QDI1; InterPro:IPR011701,IPR036259; PFAM:PF07690; TransMembrane:10 (i52-69o89-107i128-153o220-239i289-309o329-347i370- 391o403-423i435-457o463-484i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_21604S COG:E; EggNog:ENOG410PIX0; InterPro:IPR004839,IPR015424,IPR015421; PFAM:PF00155; TransMembrane:1 (o385-405i); go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0030170 - pyridoxal phosphate binding [Evidence IEA]; go_process: GO:0009058 - biosynthetic process [Evidence IEA] AKAW2_21605A COG:S; EggNog:ENOG410PPZN; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; TransMembrane:1 (o491-510i); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_21607S COG:G; EggNog:ENOG410PP2K; InterPro:IPR005000,IPR015813,IPR040442; PFAM:PF03328; go_function: GO:0003824 - catalytic activity [Evidence IEA] AKAW2_21606A COG:C,H; EggNog:ENOG410PJVZ; InterPro:IPR036188,IPR002938; PFAM:PF01494; TransMembrane:1 (n4-14c19/20o394-416i); go_function: GO:0071949 - FAD binding [Evidence IEA] AKAW2_21608S COG:P; EggNog:ENOG410Q1A6; InterPro:IPR006068,IPR018303,IPR023298,IPR023299, IPR001757,IPR006408,IPR004014,IPR036412,IPR008250, IPR023214; PFAM:PF00689,PF13246,PF00122,PF00702; TransMembrane:10 (i156-173o185-204i355-376o396-423i838-859o871-888i908- 934o989-1015i1022-1042o1048-1065i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0000166 - nucleotide binding [Evidence IEA]; go_function: GO:0005388 - calcium transmembrane transporter activity, phosphorylative mechanism [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0070588 - calcium ion transmembrane transport [Evidence IEA] AKAW2_21609S COG:S; EggNog:ENOG410PKIV; InterPro:IPR016024 AKAW2_21611S COG:C; EggNog:ENOG410PWJX; InterPro:IPR011032,IPR020843,IPR036291; PFAM:PF13602,PF00107; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA] AKAW2_21610A COG:K; EggNog:ENOG410PIN0; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_21612S CAZy:GH18; COG:G; EggNog:ENOG410PI2X; InterPro:IPR017853,IPR001223,IPR001579; PFAM:PF00704; go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_21613S COG:G; EggNog:ENOG410PI2X AKAW2_21614A InterPro:IPR036188,IPR036477,IPR038732; PFAM:PF13738,PF13454,PF07992; TransMembrane:1 (o16-33i); go_function: GO:0016742 - hydroxymethyl-, formyl-and related transferase activity [Evidence IEA]; go_process: GO:0009058 - biosynthetic process [Evidence IEA] AKAW2_21615A COG:G; EggNog:ENOG410QDAX; InterPro:IPR011701,IPR036259; PFAM:PF07690; TransMembrane:11 (o69-88i100-119o125-149i156-176o188-208i229-250o270- 289i296-316o322-340i361-381o387-407i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_21616S COG:S; EggNog:ENOG410PV7Q; InterPro:IPR036291,IPR008030; PFAM:PF13460,PF05368,PF01370 AKAW2_21617S CAZy:PL1; COG:G; EggNog:ENOG410PIPP; InterPro:IPR012334,IPR002022,IPR011050; PFAM:PF00544 AKAW2_21618A COG:T; EggNog:ENOG410PQ0Q; InterPro:IPR000719,IPR011009; PFAM:PF00069; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_21619A COG:Q; EggNog:ENOG410Q98D; InterPro:IPR036291,IPR002347,IPR020904; PFAM:PF00106,PF13561; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_21620S COG:S; EggNog:ENOG410PV32; InterPro:IPR011009,IPR002575; PFAM:PF01636 AKAW2_21621A COG:S; EggNog:ENOG410PS4H AKAW2_30001S COG:L; EggNog:ENOG410PUXI; InterPro:IPR010730; PFAM:PF06985 AKAW2_30002A COG:U; EggNog:ENOG410PH2C; InterPro:IPR022812,IPR027417,IPR001401,IPR000375, IPR030381,IPR020850; PFAM:PF00350; go_function: GO:0003924 - GTPase activity [Evidence IEA]; go_function: GO:0005525 - GTP binding [Evidence IEA] AKAW2_30004A COG:U; EggNog:ENOG410PJMS; InterPro:IPR022812,IPR027417,IPR001401,IPR000375, IPR030381,IPR020850; PFAM:PF00350,PF01031; go_function: GO:0003924 - GTPase activity [Evidence IEA]; go_function: GO:0005525 - GTP binding [Evidence IEA] AKAW2_30006A COG:M; EggNog:ENOG410QB6M; InterPro:IPR002110,IPR020683,IPR036770; PFAM:PF13857,PF12796,PF00023,PF13637,PF13606; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_30007S TransMembrane:7 (i21-38o50-70i82-102o108-126i138-157o169-187i199-220o) AKAW2_30008S COG:S; EggNog:ENOG410PPMZ; InterPro:IPR025331; PFAM:PF14021; SECRETED:SignalP(1-21) AKAW2_30009S COG:S; EggNog:ENOG410Q05M AKAW2_30012A COG:S; EggNog:ENOG410Q2MW; InterPro:IPR032880,IPR003864; PFAM:PF13967,PF02714; TransMembrane:11 (o28-49i111-130o150-168i350-379o399-421i442-466o486- 504i525-546o552-573i585-608o614-632i); go_component: GO:0016020 - membrane [Evidence IEA] AKAW2_30013S SECRETED:SignalP(1-21) AKAW2_30014S COG:S; EggNog:ENOG410QDN7; InterPro:IPR000477,IPR036397,IPR012337,IPR005135, IPR002156,IPR036691,IPR043502; PFAM:PF00078,PF14529,PF00075; TransMembrane:1 (o1011-1030i); go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0004523 - RNA-DNA hybrid ribonuclease activity [Evidence IEA] AKAW2_30015A COG:S; EggNog:ENOG410QDN7; InterPro:IPR000477,IPR036397,IPR012337,IPR005135, IPR002156,IPR036691,IPR043502; PFAM:PF00078,PF14529,PF00075; TransMembrane:1 (o1011-1030i); go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0004523 - RNA-DNA hybrid ribonuclease activity [Evidence IEA] AKAW2_30026S SECRETED:SignalP(1-25) AKAW2_30029A InterPro:IPR000210,IPR030608,IPR011333; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_30032A COG:S; EggNog:ENOG410PIY2; InterPro:IPR011009,IPR002575; PFAM:PF01636 AKAW2_30034S COG:S; EggNog:ENOG410PQVU AKAW2_30035A COG:S; EggNog:ENOG410Q5D5 AKAW2_30036S COG:S; EggNog:ENOG410Q1RM AKAW2_30037S COG:S; EggNog:ENOG410Q1RM; InterPro:IPR013087 AKAW2_30039S COG:S; EggNog:ENOG410PIBV AKAW2_30040S COG:S; EggNog:ENOG410PUUG; InterPro:IPR011009 AKAW2_30041A COG:S; EggNog:ENOG410PVIF; InterPro:IPR000210,IPR011333; PFAM:PF00651; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_30043A COG:U; EggNog:ENOG410PJMS; InterPro:IPR022812,IPR027417,IPR001401,IPR000375, IPR030381,IPR020850; PFAM:PF00350,PF01031; go_function: GO:0003924 - GTPase activity [Evidence IEA]; go_function: GO:0005525 - GTP binding [Evidence IEA] AKAW2_30044A COG:K; EggNog:ENOG410Q26E; InterPro:IPR036879,IPR002100; PFAM:PF00319; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0046983 - protein dimerization activity [Evidence IEA] AKAW2_30045A COG:S; EggNog:ENOG410PSPN AKAW2_30046A COG:S; EggNog:ENOG410PNGW; InterPro:IPR029063; PFAM:PF13489,PF08241,PF13649 AKAW2_30047A COG:S; EggNog:ENOG410Q1DK; InterPro:IPR036879,IPR002100; PFAM:PF00319; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0046983 - protein dimerization activity [Evidence IEA] AKAW2_30048S COG:K; EggNog:ENOG410Q26E; InterPro:IPR036879,IPR002100; PFAM:PF00319; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0046983 - protein dimerization activity [Evidence IEA] AKAW2_30050A COG:S; EggNog:ENOG410PT3Q AKAW2_30051A COG:S; EggNog:ENOG410PT48 AKAW2_30052A COG:S; EggNog:ENOG410Q28Y; InterPro:IPR011010,IPR013762,IPR021842; PFAM:PF11917; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_process: GO:0006310 - DNA recombination [Evidence IEA]; go_process: GO:0015074 - DNA integration [Evidence IEA] AKAW2_30053S COG:S; EggNog:ENOG410PWCE; InterPro:IPR011009,IPR002575; PFAM:PF01636 AKAW2_30054A COG:S; EggNog:ENOG410PW63; InterPro:IPR021842; PFAM:PF11917 AKAW2_30056A CAZy:CBM50; COG:S; EggNog:ENOG410QD93; InterPro:IPR018392,IPR036779; PFAM:PF01476 AKAW2_30057A COG:S; EggNog:ENOG410QD93; SECRETED:SignalP(1-18) AKAW2_30058S CAZy:GH18; COG:G; EggNog:ENOG410PI86; InterPro:IPR017853,IPR001223,IPR011583; PFAM:PF00704; go_function: GO:0008061 - chitin binding [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_30061A COG:S; EggNog:ENOG410PY13; InterPro:IPR032805; PFAM:PF13813; SECRETED:SignalP(1-22); TransMembrane:3 (i77-96o108-125i146-166o) AKAW2_30062A COG:S; EggNog:ENOG410PY13; TransMembrane:3 (o6-26i33-54o100-124i) AKAW2_30063A COG:S; EggNog:ENOG410Q2IY; InterPro:IPR038595,IPR025659,IPR007612; PFAM:PF04525 AKAW2_30064S COG:S; EggNog:ENOG410Q2W9 AKAW2_30065A COG:S; EggNog:ENOG410PKHR; InterPro:IPR018392,IPR036779; PFAM:PF01476 AKAW2_30066A COG:S; EggNog:ENOG410Q2U3 AKAW2_30067A COG:S; EggNog:ENOG410PHQ6; SECRETED:SignalP(1-20); TransMembrane:1 (n5-15c20/21o533-557i) AKAW2_30068S COG:E; EggNog:ENOG410PMDY; InterPro:IPR019818,IPR024084,IPR004429; PFAM:PF00180; go_function: GO:0000287 - magnesium ion binding [Evidence IEA]; go_function: GO:0003862 - 3-isopropylmalate dehydrogenase activity [Evidence IEA]; go_function: GO:0016616 - oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Evidence IEA]; go_function: GO:0051287 - NAD binding [Evidence IEA]; go_process: GO:0009098 - leucine biosynthetic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_30070A COG:S; EggNog:ENOG410Q02D; SECRETED:SignalP(1-19) AKAW2_30071S COG:I; EggNog:ENOG410PHKZ; InterPro:IPR036291,IPR013120; PFAM:PF07993,PF01370 AKAW2_30072A COG:Q; EggNog:ENOG410PV61; InterPro:IPR001128,IPR017972,IPR002401,IPR036396; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_30073A COG:G; EggNog:ENOG410PVXD; InterPro:IPR005829,IPR005828,IPR003663,IPR036259, IPR020846; PFAM:PF00083,PF07690; TransMembrane:12 (i35-58o87-107i114-133o139-161i173-192o204-225i306- 328o340-363i370-395o401-421i442-463o469-490i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_30074S COG:G; EggNog:ENOG410PKM1; InterPro:IPR015943,IPR019405; PFAM:PF10282; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_30075A COG:G; EggNog:ENOG410PNMQ; InterPro:IPR027417,IPR006001; go_function: GO:0016301 - kinase activity [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_30076S COG:C; EggNog:ENOG410PFT7; InterPro:IPR018170,IPR020471,IPR036812,IPR023210; PFAM:PF00248; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_30077A COG:Q; EggNog:ENOG410PJH7; InterPro:IPR020946,IPR036188; PFAM:PF13738,PF07992; go_function: GO:0004499 - N,N-dimethylaniline monooxygenase activity [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_function: GO:0050661 - NADP binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_30078S COG:S; EggNog:ENOG410PJIW; InterPro:IPR036864,IPR001138; PFAM:PF00172; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_30079S COG:S; EggNog:ENOG410PJIW; InterPro:IPR007219; TransMembrane:1 (o290-308i); go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA] AKAW2_30080A COG:S; EggNog:ENOG410PJ5H; InterPro:IPR004104,IPR000683,IPR036291; PFAM:PF02894,PF01408; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA] AKAW2_30081S COG:Q; EggNog:ENOG410PPEB; InterPro:IPR002347,IPR036291,IPR020904; PFAM:PF00106,PF13561,PF08659; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_30082A COG:E; EggNog:ENOG410PMK7; InterPro:IPR036526,IPR044149,IPR003010; PFAM:PF00795; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_process: GO:0006807 - nitrogen compound metabolic process [Evidence IEA] AKAW2_30083A COG:U; EggNog:ENOG410PW0W; InterPro:IPR011042,IPR011659; PFAM:PF07676; SECRETED:SignalP(1-24) AKAW2_30084A COG:S; EggNog:ENOG410PSHX; InterPro:IPR018392,IPR036779; PFAM:PF01476; SECRETED:SignalP(1-23) AKAW2_30086A COG:Q; EggNog:ENOG410PMFX; InterPro:IPR036291,IPR002347; PFAM:PF00106,PF13561,PF01370; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_30087S COG:C; EggNog:ENOG410PKKM; InterPro:IPR036291,IPR020843,IPR013154,IPR011032; PFAM:PF08240; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_30088A COG:S; EggNog:ENOG410PMB2; InterPro:IPR011009,IPR002575; PFAM:PF01636 AKAW2_30089A CAZy:GH13; CAZy:GT5; COG:M; EggNog:ENOG410Q1MK; InterPro:IPR013534,IPR006047,IPR017853; PFAM:PF08323,PF00128; SECRETED:SignalP(1-23); TransMembrane:13 (n9-19c23/24o1070-1095i1975-1995o2007-2026i2038-2056o2068- 2088i2100-2120o2140-2167i2187-2204o2224-2243i2250- 2267o2279-2303i2324-2346o2369-2389i); go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_30090S COG:Q; EggNog:ENOG410PIDJ; InterPro:IPR001128,IPR002403,IPR036396; PFAM:PF00067; go_function: GO:0004497 - monooxygenase activity [Evidence IEA]; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_30091S COG:P; EggNog:ENOG410PGCE; InterPro:IPR020846,IPR005828,IPR036259; PFAM:PF07690; TransMembrane:10 (i81-101o107-128i185-206o212-231i251-272o301-321i333- 352o358-375i396-418o433-451i); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_30093A COG:S; EggNog:ENOG410Q2WI; InterPro:IPR001810,IPR036047; PFAM:PF00646; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_30094S COG:S; EggNog:ENOG410PSER; InterPro:IPR000182,IPR016181; PFAM:PF13673,PF13508,PF00583; go_function: GO:0008080 - N-acetyltransferase activity [Evidence IEA] AKAW2_30095A COG:E; EggNog:ENOG410PMWM; InterPro:IPR006076,IPR036188; PFAM:PF01266,PF13450; TransMembrane:1 (i7-24o); go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_30096S COG:P; EggNog:ENOG410PH2B; InterPro:IPR036922,IPR017941,IPR015879,IPR001663; PFAM:PF00355; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0051537 - 2 iron, 2 sulfur cluster binding [Evidence IEA]; go_process: GO:0044237 - cellular metabolic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_30097S COG:K; EggNog:ENOG410PKVB; InterPro:IPR036864,IPR001138; PFAM:PF00172; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_30098A CAZy:CE10; COG:I; EggNog:ENOG410PP4C; InterPro:IPR029058,IPR013094; MEROPS:MER0033242; PFAM:PF07859; TransMembrane:1 (o23-46i); go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_30101S COG:K; EggNog:ENOG410Q1FS; InterPro:IPR007219; PFAM:PF04082; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA] AKAW2_30102A COG:H; EggNog:ENOG410PUQM; InterPro:IPR001645,IPR036615,IPR023600,IPR036565; go_function: GO:0004326 - tetrahydrofolylpolyglutamate synthase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016874 - ligase activity [Evidence IEA]; go_process: GO:0009058 - biosynthetic process [Evidence IEA]; go_process: GO:0009396 - folic acid-containing compound biosynthetic process [Evidence IEA] AKAW2_30103S COG:G; EggNog:ENOG410PFF2; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i57-78o90-112i124-142o148-171i183-208o214-233i299- 319o331-351i390-408o420-445i457-474o480-504i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_30104S COG:I; EggNog:ENOG410PVRU; InterPro:IPR042099,IPR000873,IPR020845; PFAM:PF00501 AKAW2_30105S COG:I; EggNog:ENOG410PVRU AKAW2_30106S COG:S; EggNog:ENOG410PP0S; InterPro:IPR037401,IPR032710; PFAM:PF13577 AKAW2_30107A COG:I; EggNog:ENOG410PMHS; InterPro:IPR002018,IPR029058; MEROPS:MER0033188; PFAM:PF00135,PF07859; SECRETED:SignalP(1-19) AKAW2_30109A CAZy:GH28; COG:G; EggNog:ENOG410PKB6; InterPro:IPR000743,IPR012334,IPR011050; PFAM:PF00295; SECRETED:SignalP(1-18); go_function: GO:0004650 - polygalacturonase activity [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_30110S CAZy:CE8; COG:G; EggNog:ENOG410PHJI; InterPro:IPR000070,IPR033131,IPR011050,IPR012334; PFAM:PF01095; SECRETED:SignalP(1-19); go_function: GO:0030599 - pectinesterase activity [Evidence IEA]; go_process: GO:0042545 - cell wall modification [Evidence IEA] AKAW2_30111S COG:S; EggNog:ENOG410PNRA; InterPro:IPR000791,IPR030186; PFAM:PF01184; TransMembrane:6 (o40-60i72-92o98-124i136-155o161-183i195-219o); go_component: GO:0016021 - integral component of membrane [Evidence IEA] AKAW2_30112S COG:I; EggNog:ENOG410PGUT; InterPro:IPR013107,IPR013786,IPR009100,IPR036250, IPR037069; PFAM:PF02771,PF08028; go_function: GO:0016627 - oxidoreductase activity, acting on the CH-CH group of donors [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_30113S CAZy:GH76; COG:G; EggNog:ENOG410PN11; InterPro:IPR005198,IPR008928; PFAM:PF03663; SECRETED:SignalP(1-18); go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_30114S COG:S; EggNog:ENOG410PQAJ; InterPro:IPR011333 AKAW2_30115S COG:B; EggNog:ENOG410PK2I; InterPro:IPR001214; PFAM:PF00856; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_30116S COG:E; EggNog:ENOG410QDM2; InterPro:IPR004841; PFAM:PF13520,PF00324; TransMembrane:11 (o44-65i77-100o120-143i150-173o179-198i274-295o334- 358i379-396o408-433i454-476o482-502i); go_component: GO:0016020 - membrane [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_30117A COG:S; EggNog:ENOG410Q0AR; InterPro:IPR022703; PFAM:PF12051; TransMembrane:7 (o31-51i224-245o265-289i301-326o332-351i358-375o387-406i) AKAW2_30118S COG:S; EggNog:ENOG410PTAN AKAW2_30119A COG:S; EggNog:ENOG410PTYH AKAW2_30120S COG:S; EggNog:ENOG410PWUD; InterPro:IPR011009,IPR002575,IPR008266; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_30121S COG:S; EggNog:ENOG410PUHG; InterPro:IPR011009,IPR002575; PFAM:PF01636 AKAW2_30122A COG:G; EggNog:ENOG410PUJS; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:9 (o12-32i53-75o81-102i163-181o201-222i243-263o269-293i305- 325o337-358i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_30124S COG:S; EggNog:ENOG410Q1MG; InterPro:IPR021054; PFAM:PF12296; SECRETED:SignalP(1-19) AKAW2_30125S COG:Q; EggNog:ENOG410PJKT; InterPro:IPR020946,IPR036188; PFAM:PF07992,PF13738,PF13450; TransMembrane:2 (o14-36i536-555o); go_function: GO:0004499 - N,N-dimethylaniline monooxygenase activity [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_function: GO:0050661 - NADP binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_30126A COG:E; EggNog:ENOG410QDM5; InterPro:IPR004841; PFAM:PF13520,PF00324; TransMembrane:12 (i62-81o87-107i128-149o169-191i203-224o250-272i292- 310o345-364i385-407o419-440i465-487o493-512i); go_component: GO:0016020 - membrane [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_30127A COG:S; EggNog:ENOG410PNHN; InterPro:IPR027417 AKAW2_30128A COG:Q; EggNog:ENOG410PVQY; InterPro:IPR000269,IPR015798,IPR016182,IPR036460; PFAM:PF01179; go_function: GO:0005507 - copper ion binding [Evidence IEA]; go_function: GO:0008131 - primary amine oxidase activity [Evidence IEA]; go_function: GO:0048038 - quinone binding [Evidence IEA]; go_process: GO:0009308 - amine metabolic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_30129S COG:K; EggNog:ENOG410PIZZ; InterPro:IPR001005,IPR009057,IPR017930; PFAM:PF00249,PF13921 AKAW2_30130A COG:C; EggNog:ENOG410QE5F; InterPro:IPR036291,IPR029752,IPR006140; go_function: GO:0051287 - NAD binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_30131A TransMembrane:1 (o66-85i) AKAW2_30132S COG:C; EggNog:ENOG410PKHE; InterPro:IPR037396,IPR000262,IPR008259,IPR013785; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_30133S COG:S; EggNog:ENOG410PGZZ; InterPro:IPR017850,IPR000917; PFAM:PF00884; TransMembrane:6 (o35-53i65-85o97-123i144-166o172-189i248-267o); go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0008484 - sulfuric ester hydrolase activity [Evidence IEA] AKAW2_30134S COG:S; EggNog:ENOG410PMHG; InterPro:IPR011009,IPR002575 AKAW2_30135A COG:I; EggNog:ENOG410PGIY; InterPro:IPR000873,IPR020845,IPR042099,IPR025110; PFAM:PF00501,PF13193 AKAW2_30136A COG:E; EggNog:ENOG410PHHD; InterPro:IPR013057; PFAM:PF01490; TransMembrane:11 (i55-74o80-104i132-154o166-183i195-215o235-254i266- 287o307-326i347-368o380-401i413-436o) AKAW2_30137A COG:Q; EggNog:ENOG410PJB5; InterPro:IPR002347,IPR036291,IPR020904; PFAM:PF00106,PF13561,PF08659; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_30138A CAZy:GT2_Glyco_tranf_2; COG:U; EggNog:ENOG410PGTI; InterPro:IPR029044; PFAM:PF13632,PF13641; TransMembrane:7 (o250-273i280-298o383-401i559-575o595-614i619-637o657- 678i) AKAW2_30139A COG:H; EggNog:ENOG410PNPC; InterPro:IPR025714,IPR029063; PFAM:PF01135,PF13649,PF13489,PF01209,PF08242, PF08241,PF13847 AKAW2_30140A COG:E; EggNog:ENOG410QDKX; InterPro:IPR004841; PFAM:PF13520,PF00324; TransMembrane:12 (i58-77o89-112i124-145o165-187i199-216o245-265i286- 304o343-362i392-419o425-444i464-488o494-513i); go_component: GO:0016020 - membrane [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_30141S CAZy:CE12; COG:E; EggNog:ENOG410PRJI; InterPro:IPR013830,IPR036514,IPR037459; PFAM:PF13472; SECRETED:SignalP(1-15); go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_30142S COG:K; EggNog:ENOG410PHVP; InterPro:IPR036236,IPR013087,IPR007219; PFAM:PF00096,PF04082; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA] AKAW2_30143A COG:S; EggNog:ENOG410PMD0; InterPro:IPR018843; PFAM:PF10395 AKAW2_30144S COG:O; EggNog:ENOG410QDMT; InterPro:IPR027417,IPR003593,IPR003959; PFAM:PF00004,PF07728; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA] AKAW2_30145S COG:U; EggNog:ENOG410PHPQ; InterPro:IPR027267,IPR035704,IPR001683,IPR028662, IPR036871; PFAM:PF00787; go_function: GO:0035091 - phosphatidylinositol binding [Evidence IEA]; go_process: GO:0042147 - retrograde transport, endosome to Golgi [Evidence IEA] AKAW2_30146S COG:P; EggNog:ENOG410PFD4; InterPro:IPR038770,IPR006153,IPR013928,IPR004712; PFAM:PF00999,PF08619; TransMembrane:11 (o12-32i102-124o130-153i174-190o202-226i246-262o268- 284i296-315o327-349i361-382o412-437i); go_component: GO:0005886 - plasma membrane [Evidence IEA]; go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0015299 - solute:proton antiporter activity [Evidence IEA]; go_function: GO:0015385 - sodium:proton antiporter activity [Evidence IEA]; go_process: GO:0006812 - cation transport [Evidence IEA]; go_process: GO:0006814 - sodium ion transport [Evidence IEA]; go_process: GO:0030004 - cellular monovalent inorganic cation homeostasis [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_30147A COG:T; EggNog:ENOG410PUBJ AKAW2_30148S COG:S; EggNog:ENOG410PY9G AKAW2_30149A COG:O; EggNog:ENOG410PGP0; InterPro:IPR041569,IPR003959,IPR003338,IPR029067, IPR027417,IPR003593,IPR003960,IPR009010,IPR005938, IPR015415,IPR004201; PFAM:PF09336,PF02359,PF17862,PF00004,PF07724, PF07728,PF02933; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016787 - hydrolase activity [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA] AKAW2_30150S COG:S; EggNog:ENOG410PYS0; InterPro:IPR036568,IPR009288,IPR013024; PFAM:PF06094 AKAW2_30151A COG:S; EggNog:ENOG410PT34; InterPro:IPR008733; PFAM:PF05648; TransMembrane:2 (i191-208o234-254i); go_component: GO:0005779 - integral component of peroxisomal membrane [Evidence IEA]; go_process: GO:0016559 - peroxisome fission [Evidence IEA] AKAW2_30152A COG:S; EggNog:ENOG410Q0RV AKAW2_30153S COG:S; EggNog:ENOG410PFT6; InterPro:IPR007248; PFAM:PF04117; TransMembrane:4 (i86-109o121-146i158-179o185-202i); go_component: GO:0016021 - integral component of membrane [Evidence IEA] AKAW2_30154A COG:J; EggNog:ENOG410PNT9; InterPro:IPR005176,IPR014764,IPR009060; PFAM:PF03556,PF14555; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_30155S BUSCO:EOG092629WJ; COG:J,U; EggNog:ENOG410PGMN; InterPro:IPR016024,IPR016903,IPR005612,IPR011501; PFAM:PF03914,PF07540 AKAW2_30156A COG:S; EggNog:ENOG410Q2V1 AKAW2_30157A COG:S; EggNog:ENOG410PSRA; InterPro:IPR013783,IPR014756; TransMembrane:1 (o1514-1534i) AKAW2_30158A CAZy:CBM67; CAZy:GH78; COG:S; EggNog:ENOG410PIJS; InterPro:IPR016007,IPR008928,IPR013783,IPR035396, IPR008902,IPR013737,IPR035398,IPR012341; PFAM:PF17390,PF17389,PF05592,PF08531; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_30159A COG:S; EggNog:ENOG410PVJN; InterPro:IPR009784; PFAM:PF07081 AKAW2_30160S COG:S; EggNog:ENOG410PR9T; InterPro:IPR019367; PFAM:PF10235 AKAW2_30161A BUSCO:EOG09263FAK; COG:J; EggNog:ENOG410PMZF; InterPro:IPR040008,IPR015797,IPR021757; PFAM:PF11788; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_30162A COG:L; EggNog:ENOG410PJ2I; InterPro:IPR036397,IPR012337,IPR006941; PFAM:PF04857; go_function: GO:0003676 - nucleic acid binding [Evidence IEA] AKAW2_30164S COG:S; EggNog:ENOG410PJ0F; TransMembrane:1 (o388-406i) AKAW2_30163A COG:P; EggNog:ENOG410PHG1; InterPro:IPR016833,IPR038770; PFAM:PF01758,PF13593; TransMembrane:8 (i21-44o59-76i88-114o126-145i157-180o207-225i246-265o271- 292i) AKAW2_30165S COG:C; EggNog:ENOG410PFV9; InterPro:IPR018108,IPR023395 AKAW2_30166S COG:W; EggNog:ENOG410PK0U; InterPro:IPR028458,IPR029006,IPR002108; PFAM:PF00241; go_function: GO:0003779 - actin binding [Evidence IEA]; go_process: GO:0030837 - negative regulation of actin filament polymerization [Evidence IEA] AKAW2_30167S COG:S; EggNog:ENOG410PRS1; InterPro:IPR006786,IPR039853; PFAM:PF04696 AKAW2_30168S COG:I; EggNog:ENOG410QDEM; InterPro:IPR000073,IPR029058,IPR000639; MEROPS:MER0017177; PFAM:PF12697,PF12146; go_function: GO:0003824 - catalytic activity [Evidence IEA] AKAW2_30169A COG:S; EggNog:ENOG410PHFU; InterPro:IPR036291,IPR005097; PFAM:PF03435; TransMembrane:1 (o281-300i); go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_30170S COG:J; EggNog:ENOG410PQ1G; InterPro:IPR002674,IPR011332,IPR011331; PFAM:PF01780; go_component: GO:0005840 - ribosome [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_process: GO:0006412 - translation [Evidence IEA] AKAW2_30171S COG:O; EggNog:ENOG410QD8E; InterPro:IPR001841,IPR019787,IPR011011,IPR001965, IPR013083; PFAM:PF00097,PF00628,PF13639 AKAW2_30172S COG:G; EggNog:ENOG410PFTW; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i109-134o146-164i176-194o200-222i234-254o266-286i337- 361o381-400i421-441o447-467i479-503o515-537i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_30173S BUSCO:EOG09262PMC; COG:D; EggNog:ENOG410PFZ5; InterPro:IPR039776,IPR016024,IPR011989; go_process: GO:0007064 - mitotic sister chromatid cohesion [Evidence IEA] AKAW2_30174A BUSCO:EOG0926115P; COG:B,K; EggNog:ENOG410PHVG; InterPro:IPR006939; PFAM:PF04855; go_component: GO:0000228 - nuclear chromosome [Evidence IEA]; go_process: GO:0006338 - chromatin remodeling [Evidence IEA] AKAW2_30175A COG:T; EggNog:ENOG410PN4X; InterPro:IPR036691,IPR005135; PFAM:PF03372 AKAW2_30176A CAZy:AA3; COG:E; EggNog:ENOG410PJHS; InterPro:IPR012132,IPR036188,IPR000172,IPR007867; PFAM:PF05199,PF00732; go_function: GO:0016614 - oxidoreductase activity, acting on CH-OH group of donors [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_30177A COG:S; EggNog:ENOG410PXSX; TransMembrane:7 (o22-43i63-81o101-123i135-157o180-202i214-233o253-277i) AKAW2_30178S COG:J; EggNog:ENOG410PM2V; InterPro:IPR036005,IPR000994,IPR036388,IPR036390; MEROPS:MER0064643; PFAM:PF00557 AKAW2_30179S BUSCO:EOG09262TEV; COG:J; EggNog:ENOG410PM4K; InterPro:IPR019787,IPR019786,IPR011011,IPR001965, IPR013083; PFAM:PF00628 AKAW2_30180A COG:U; EggNog:ENOG410PIPQ; InterPro:IPR005052,IPR035661,IPR013320; PFAM:PF03388; SECRETED:SignalP(1-16); TransMembrane:1 (n3-11c16/17o382-403i); go_component: GO:0016020 - membrane [Evidence IEA] AKAW2_30182S CAZy:GT57; COG:G; EggNog:ENOG410PIKP; InterPro:IPR004856,IPR039487; PFAM:PF03155; TransMembrane:12 (i7-26o97-116i128-145o151-168i175-201o221-242i319-336o342- 362i383-402o408-426i446-466o478-500i); go_component: GO:0005783 - endoplasmic reticulum [Evidence IEA]; go_function: GO:0016758 - transferase activity, transferring hexosyl groups [Evidence IEA]; go_function: GO:0042283 - dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity [Evidence IEA]; go_process: GO:0006490 - oligosaccharide-lipid intermediate biosynthetic process [Evidence IEA] AKAW2_30183S COG:B; EggNog:ENOG410QDJS; InterPro:IPR018501,IPR028941,IPR013136,IPR028942; PFAM:PF02791,PF15613,PF15612,PF10537 AKAW2_30184S COG:C; EggNog:ENOG410PG91; InterPro:IPR018108,IPR023395,IPR002067,IPR002167; PFAM:PF00153; TransMembrane:1 (o404-426i); go_component: GO:0005743 - mitochondrial inner membrane [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_30185S COG:K; EggNog:ENOG410PHQE; InterPro:IPR035979,IPR012677,IPR034353,IPR039119; go_function: GO:0003676 - nucleic acid binding [Evidence IEA] AKAW2_30186A BUSCO:EOG09262CA4; COG:J; EggNog:ENOG410PFAM; InterPro:IPR007064,IPR039768; PFAM:PF04981; go_function: GO:0043023 - ribosomal large subunit binding [Evidence IEA] AKAW2_30187S COG:A; EggNog:ENOG410PPFC; InterPro:IPR040152,IPR043519; PFAM:PF02410; go_process: GO:0140053 - mitochondrial gene expression [Evidence IEA] AKAW2_30188S COG:O; EggNog:ENOG410PK77; InterPro:IPR001841,IPR006845,IPR017375,IPR013083; PFAM:PF04757; go_component: GO:0005779 - integral component of peroxisomal membrane [Evidence IEA]; go_function: GO:0008022 - protein C-terminus binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006625 - protein targeting to peroxisome [Evidence IEA] AKAW2_30189A CAZy:GH125; COG:S; EggNog:ENOG410PFTS; InterPro:IPR008928,IPR012341,IPR008313; PFAM:PF06824; SECRETED:SignalP(1-21); go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_30190A COG:F; EggNog:ENOG410PPPE; InterPro:IPR019038; PFAM:PF09507; go_component: GO:0005634 - nucleus [Evidence IEA]; go_component: GO:0043625 - delta DNA polymerase complex [Evidence IEA]; go_process: GO:0006260 - DNA replication [Evidence IEA] AKAW2_30191S COG:L; EggNog:ENOG410PJ1F; InterPro:IPR001841,IPR003034,IPR017907,IPR004580, IPR039577,IPR006642,IPR013083; PFAM:PF14634,PF13920,PF00097,PF13445,PF02037, PF13923; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0003697 - single-stranded DNA binding [Evidence IEA]; go_function: GO:0061630 - ubiquitin protein ligase activity [Evidence IEA]; go_process: GO:0006281 - DNA repair [Evidence IEA]; go_process: GO:0006301 - postreplication repair [Evidence IEA]; go_process: GO:0006513 - protein monoubiquitination [Evidence IEA] AKAW2_30192A COG:U; EggNog:ENOG410PIFR; InterPro:IPR005024; PFAM:PF03357; go_process: GO:0007034 - vacuolar transport [Evidence IEA] AKAW2_30193A BUSCO:EOG09260W8D; COG:D; EggNog:ENOG410PKG3; InterPro:IPR024420; PFAM:PF12739 AKAW2_30194S COG:J; EggNog:ENOG410PHA4; InterPro:IPR043519,IPR032828,IPR002646; PFAM:PF12627,PF01743; go_function: GO:0003723 - RNA binding [Evidence IEA]; go_function: GO:0016779 - nucleotidyltransferase activity [Evidence IEA]; go_process: GO:0006396 - RNA processing [Evidence IEA] AKAW2_30196S COG:S; EggNog:ENOG410PS8X; InterPro:IPR018870,IPR016024; PFAM:PF10521 AKAW2_30197S COG:S; EggNog:ENOG410Q2QJ; InterPro:IPR022190; PFAM:PF12511 AKAW2_30198A COG:S; EggNog:ENOG410Q2DN; TransMembrane:6 (o23-42i54-76o88-110i122-143o163-181i202-227o) AKAW2_30200A COG:S; EggNog:ENOG410PWEH; InterPro:IPR011009,IPR002575; PFAM:PF01636 AKAW2_30201S COG:E; EggNog:ENOG410PW4J; InterPro:IPR036038,IPR001544,IPR043131,IPR043132; PFAM:PF01063; go_function: GO:0003824 - catalytic activity [Evidence IEA] AKAW2_30202S COG:S; EggNog:ENOG410PVFN; InterPro:IPR036864,IPR001138; PFAM:PF00172; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_30203A COG:S; EggNog:ENOG410Q2CA AKAW2_30204A COG:K; EggNog:ENOG410Q2S7; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; TransMembrane:1 (o732-752i); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_30205A COG:L,T; EggNog:ENOG410PGC3; InterPro:IPR036155,IPR005101,IPR006050,IPR002081, IPR036134,IPR018394,IPR014729; PFAM:PF03441,PF00875 AKAW2_30206S COG:T; EggNog:ENOG410QE1U; InterPro:IPR000719,IPR011009,IPR008271,IPR017441; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_30207S COG:C; EggNog:ENOG410Q4IX; InterPro:IPR037458,IPR001199,IPR037396,IPR013785, IPR036400,IPR000262,IPR018506; PFAM:PF00173,PF01070; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA] AKAW2_30208S CAZy:AA9; COG:G; EggNog:ENOG410PNFI; InterPro:IPR005103; PFAM:PF03443; SECRETED:SignalP(1-25) AKAW2_30209S SECRETED:SignalP(1-18) AKAW2_30210S COG:Q; EggNog:ENOG410PMKW; InterPro:IPR001128,IPR017972,IPR002401,IPR036396; PFAM:PF00067; TransMembrane:1 (o12-32i); go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_30211A COG:O; EggNog:ENOG410PZ95; SECRETED:SignalP(1-17) AKAW2_30212A COG:E; EggNog:ENOG410Q1DS; InterPro:IPR005645,IPR029058; PFAM:PF03959; TransMembrane:2 (i116-136o156-173i) AKAW2_30213S BUSCO:EOG09264CP4; COG:U; EggNog:ENOG410PFNM; InterPro:IPR010908,IPR042855,IPR001388,IPR011012; PFAM:PF00957,PF13774; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_process: GO:0016192 - vesicle-mediated transport [Evidence IEA] AKAW2_30214S COG:S; EggNog:ENOG410Q2E3; InterPro:IPR038781; TransMembrane:3 (n25-36c41/42o57-76i120-140o160-183i) AKAW2_30215S COG:Q; EggNog:ENOG410PHH6; InterPro:IPR001128,IPR002401,IPR036396; PFAM:PF00067; TransMembrane:3 (o20-41i53-73o79-101i); go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_30216S COG:S; EggNog:ENOG410Q1IM AKAW2_30217A COG:S; EggNog:ENOG410PN8G; InterPro:IPR036864,IPR021858,IPR001138; PFAM:PF00172; TransMembrane:1 (o418-437i); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_30218S COG:Q; EggNog:ENOG410PUIW; InterPro:IPR001128,IPR017972,IPR002401,IPR036396; PFAM:PF00067; TransMembrane:1 (o6-26i); go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_30220A COG:Q; EggNog:ENOG410PN36; InterPro:IPR036291,IPR002347; PFAM:PF08659,PF00106,PF13561; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_30221A COG:S; EggNog:ENOG410PNIB; InterPro:IPR002213,IPR007130; PFAM:PF03982; TransMembrane:1 (o351-372i); go_function: GO:0008194 - UDP-glycosyltransferase activity [Evidence IEA]; go_function: GO:0016747 - transferase activity, transferring acyl groups other than amino-acyl groups [Evidence IEA] AKAW2_30222A COG:S; EggNog:ENOG410PNIB AKAW2_30223S COG:Q; EggNog:ENOG410Q1HP; InterPro:IPR001128,IPR002401,IPR036396; PFAM:PF00067; TransMembrane:1 (o20-38i); go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_30224S COG:Q; EggNog:ENOG410PGKJ; InterPro:IPR017871,IPR027417,IPR003593,IPR039421, IPR011527,IPR003439,IPR036640; PFAM:PF00005,PF00664; TransMembrane:10 (i58-82o109-133i185-203o209-234i288-310o766-791i837- 863o869-890i951-972o984-1004i); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA]; go_function: GO:0042626 - ATPase-coupled transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_30225S BUSCO:EOG09264O9F; COG:F; EggNog:ENOG410QECU; InterPro:IPR029057,IPR000836,IPR004467,IPR023031; PFAM:PF00156; go_function: GO:0004588 - orotate phosphoribosyltransferase activity [Evidence IEA]; go_process: GO:0006221 - pyrimidine nucleotide biosynthetic process [Evidence IEA]; go_process: GO:0009116 - nucleoside metabolic process [Evidence IEA] AKAW2_30226S COG:G; EggNog:ENOG410PFTW; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690,PF00083; TransMembrane:12 (i116-143o149-172i184-203o209-231i243-266o278-301i348- 373o385-405i425-444o450-473i485-507o519-541i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_30227S COG:G; EggNog:ENOG410PHIB; InterPro:IPR005829,IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i59-76o96-116i128-147o153-177i189-208o214-236i296- 315o335-355i376-395o401-422i434-457o469-488i); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_30228A COG:S; EggNog:ENOG410Q1SS; InterPro:IPR021833; PFAM:PF11905 AKAW2_30229A COG:T; EggNog:ENOG410PM5P; InterPro:IPR011009 AKAW2_30230A COG:T; EggNog:ENOG410PM5P; InterPro:IPR000719,IPR011009,IPR008271,IPR017441; PFAM:PF00069; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_30231A COG:T; EggNog:ENOG410PWZ8; InterPro:IPR011009; TransMembrane:1 (o60-79i) AKAW2_30232A COG:G; EggNog:ENOG410PJTF; InterPro:IPR000121,IPR015813,IPR040442; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0016772 - transferase activity, transferring phosphorus-containing groups [Evidence IEA]; go_process: GO:0016310 - phosphorylation [Evidence IEA] AKAW2_30233A COG:G; EggNog:ENOG410Q1GM; InterPro:IPR019180; PFAM:PF09791 AKAW2_30234A COG:C; EggNog:ENOG410PPGS; InterPro:IPR038662,IPR035921,IPR000454,IPR020537, IPR002379; PFAM:PF00137; TransMembrane:2 (i97-117o129-151i); go_component: GO:0033177 - proton-transporting two-sector ATPase complex, proton-transporting domain [Evidence IEA]; go_component: GO:0045263 - proton-transporting ATP synthase complex, coupling factor F(o) [Evidence IEA]; go_function: GO:0015078 - proton transmembrane transporter activity [Evidence IEA]; go_process: GO:0015986 - ATP synthesis coupled proton transport [Evidence IEA]; go_process: GO:1902600 - proton transmembrane transport [Evidence IEA] AKAW2_30235A COG:S; EggNog:ENOG410PI76; InterPro:IPR037291,IPR011935; PFAM:PF13598 AKAW2_30236A COG:S; EggNog:ENOG410PI76; InterPro:IPR011935,IPR025554; PFAM:PF13600 AKAW2_30238A SECRETED:SignalP(1-23) AKAW2_30239A COG:S; EggNog:ENOG410Q2G7; InterPro:IPR000182,IPR016181; PFAM:PF00583; go_function: GO:0008080 - N-acetyltransferase activity [Evidence IEA] AKAW2_30240A COG:E; EggNog:ENOG410Q0BE; InterPro:IPR006151,IPR036291,IPR041121,IPR013708; PFAM:PF08501,PF01488,PF18317; go_function: GO:0004764 - shikimate 3-dehydrogenase (NADP+) activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_30241A COG:S; EggNog:ENOG410PUNC; InterPro:IPR037401,IPR032710; PFAM:PF13577 AKAW2_30242S COG:E; EggNog:ENOG410PJVV; InterPro:IPR036291,IPR013708; PFAM:PF08501; go_function: GO:0004764 - shikimate 3-dehydrogenase (NADP+) activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_30244S COG:H; EggNog:ENOG410QE8H; InterPro:IPR013022,IPR036237; PFAM:PF01261 AKAW2_30243A COG:K; EggNog:ENOG410QEIR; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172; TransMembrane:2 (i276-296o434-455i); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_30245S COG:K; EggNog:ENOG410Q192; InterPro:IPR001381,IPR006151,IPR027417,IPR036291, IPR013708,IPR041121,IPR013785,IPR031322; PFAM:PF01202,PF08501,PF01487,PF18317; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0003855 - 3-dehydroquinate dehydratase activity [Evidence IEA]; go_function: GO:0004764 - shikimate 3-dehydrogenase (NADP+) activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_30246A COG:S; EggNog:ENOG410Q1JI AKAW2_30247S COG:S; EggNog:ENOG410PNEP AKAW2_30248A COG:S; EggNog:ENOG410PH9W; InterPro:IPR036864,IPR021858,IPR001138; PFAM:PF00172,PF11951; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_30249A COG:G; EggNog:ENOG410PFEN; InterPro:IPR005828,IPR003663,IPR036259,IPR020846; PFAM:PF00083,PF07690; TransMembrane:11 (o65-82i89-111o117-136i148-166o178-200i271-293o313- 335i342-362o368-395i407-427o433-451i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_30250S COG:Q; EggNog:ENOG410PGNV; InterPro:IPR002347,IPR036291,IPR020904; PFAM:PF00106,PF13561,PF08659; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_30251S COG:S; EggNog:ENOG410Q2IJ; TransMembrane:1 (i132-156o) AKAW2_30252S COG:S; EggNog:ENOG410Q1IK; SECRETED:SignalP(1-19); TransMembrane:1 (n3-14c19/20o1397-1416i) AKAW2_30253S COG:G; EggNog:ENOG410QDAZ; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i60-80o100-120i132-151o157-177i189-209o221-241i262- 281o301-319i326-348o354-379i391-415o421-439i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_30255S COG:S; EggNog:ENOG410Q1UN AKAW2_30254A COG:K,L; EggNog:ENOG410PM2K; InterPro:IPR036322,IPR015943,IPR001680,IPR019775, IPR020472,IPR042238,IPR017986; PFAM:PF00400; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0006283 - transcription-coupled nucleotide-excision repair [Evidence IEA] AKAW2_30256S COG:S; EggNog:ENOG410PQEZ; InterPro:IPR022793; go_process: GO:0006360 - transcription by RNA polymerase I [Evidence IEA] AKAW2_30259S COG:D; EggNog:ENOG410PS3S; InterPro:IPR040453,IPR005647; PFAM:PF03962; go_function: GO:0003690 - double-stranded DNA binding [Evidence IEA]; go_process: GO:0007131 - reciprocal meiotic recombination [Evidence IEA] AKAW2_30260S COG:K; EggNog:ENOG410PIHK; InterPro:IPR014756,IPR011021,IPR011022,IPR014752; PFAM:PF00339 AKAW2_30261S COG:U; EggNog:ENOG410PNPV; InterPro:IPR013248; PFAM:PF08229; TransMembrane:3 (n4-15c20/21o53-74i81-100o147-165i) AKAW2_30262A COG:S; EggNog:ENOG410PMR8 AKAW2_30263A COG:S; EggNog:ENOG410PS1X AKAW2_30264A COG:T; EggNog:ENOG410PV4U; InterPro:IPR000719,IPR011009; PFAM:PF00069; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_30266A COG:K; EggNog:ENOG410PFWM; InterPro:IPR036864,IPR021858,IPR001138; PFAM:PF00172,PF11951; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_30268S COG:O; EggNog:ENOG410PKTX; InterPro:IPR001915; MEROPS:MER0026545; PFAM:PF01435; TransMembrane:1 (i97-115o); go_function: GO:0004222 - metalloendopeptidase activity [Evidence IEA]; go_process: GO:0006508 - proteolysis [Evidence IEA] AKAW2_30269S COG:C,H; EggNog:ENOG410Q0BF; InterPro:IPR036188,IPR002938; go_function: GO:0071949 - FAD binding [Evidence IEA] AKAW2_30270S COG:Q; EggNog:ENOG410QD7U; InterPro:IPR013154,IPR029063,IPR036291,IPR013217, IPR011032,IPR020843; PFAM:PF13649,PF08240,PF08242,PF08241,PF13847; TransMembrane:1 (o423-442i); go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_30272S COG:Q; EggNog:ENOG410PFZD; InterPro:IPR036291,IPR013968; PFAM:PF08659 AKAW2_30273S COG:O; EggNog:ENOG410PGJ7; InterPro:IPR002423,IPR012721,IPR027410,IPR027413, IPR017998,IPR002194,IPR027409; PFAM:PF00118; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0051082 - unfolded protein binding [Evidence IEA]; go_process: GO:0006457 - protein folding [Evidence IEA] AKAW2_30274S BUSCO:EOG09265HPJ; COG:J; EggNog:ENOG410PPSM; InterPro:IPR036235,IPR013823,IPR000206,IPR014719, IPR008932; PFAM:PF00542,PF16320; go_component: GO:0005840 - ribosome [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_process: GO:0006412 - translation [Evidence IEA] AKAW2_30275A COG:S; EggNog:ENOG410PP3Q; InterPro:IPR038491,IPR021740,IPR037525 AKAW2_30278A COG:S; EggNog:ENOG410PY0K; TransMembrane:2 (i182-199o205-227i) AKAW2_30279S COG:A; EggNog:ENOG410PM31; InterPro:IPR013260; PFAM:PF08231 AKAW2_30280A BUSCO:EOG09262ZZ8; COG:I; EggNog:ENOG410PGBG; InterPro:IPR036291,IPR001509; go_function: GO:0003824 - catalytic activity [Evidence IEA] AKAW2_30281S BUSCO:EOG09262UTQ; COG:B; EggNog:ENOG410PGXN; InterPro:IPR038704,IPR005033; PFAM:PF03366; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_30282A COG:K; EggNog:ENOG410PV4G; InterPro:IPR007219; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA] AKAW2_30283A COG:E; EggNog:ENOG410PW2S; InterPro:IPR014710,IPR010300,IPR011051; PFAM:PF05995; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016702 - oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_30284A COG:S; EggNog:ENOG410PIQ1; InterPro:IPR001279,IPR036866; PFAM:PF00753 AKAW2_30285A COG:E; EggNog:ENOG410PFRQ; InterPro:IPR037217,IPR000898; PFAM:PF01231; go_function: GO:0020037 - heme binding [Evidence IEA]; go_function: GO:0046872 - metal ion binding [Evidence IEA]; go_process: GO:0019441 - tryptophan catabolic process to kynurenine [Evidence IEA] AKAW2_30286S COG:E; EggNog:ENOG410PH7Q; InterPro:IPR000192,IPR015424,IPR010111,IPR015422, IPR015421; go_component: GO:0005737 - cytoplasm [Evidence IEA]; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0030170 - pyridoxal phosphate binding [Evidence IEA]; go_function: GO:0030429 - kynureninase activity [Evidence IEA]; go_process: GO:0006569 - tryptophan catabolic process [Evidence IEA]; go_process: GO:0009435 - NAD biosynthetic process [Evidence IEA] AKAW2_30287A COG:K; EggNog:ENOG410PVXM; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_30288A COG:S; EggNog:ENOG410PT1T; InterPro:IPR039297; PFAM:PF02238; TransMembrane:1 (o44-63i) AKAW2_30289S COG:S; EggNog:ENOG410PMZR AKAW2_30290S COG:S; EggNog:ENOG410PJQT; InterPro:IPR017946; SECRETED:SignalP(1-17); go_function: GO:0008081 - phosphoric diester hydrolase activity [Evidence IEA]; go_process: GO:0006629 - lipid metabolic process [Evidence IEA] AKAW2_30291A COG:S; EggNog:ENOG410PQQV; InterPro:IPR002767,IPR029756; PFAM:PF01910 AKAW2_30292S COG:S; EggNog:ENOG410PS6V; InterPro:IPR009286; PFAM:PF06090; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0035299 - inositol pentakisphosphate 2-kinase activity [Evidence IEA] AKAW2_30293S COG:S; EggNog:ENOG410PJVI; InterPro:IPR033877,IPR029479,IPR000415; PFAM:PF00881; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0016657 - oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor [Evidence IEA]; go_process: GO:0034599 - cellular response to oxidative stress [Evidence IEA] AKAW2_30294S CAZy:CE4; COG:G; EggNog:ENOG410PP58; InterPro:IPR002509,IPR011330; PFAM:PF01522; SECRETED:SignalP(1-25); go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0016810 - hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_30295A COG:D; EggNog:ENOG410PR0S; InterPro:IPR000719,IPR011009; PFAM:PF12330; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_30296S BUSCO:EOG09261S0S; COG:M; EggNog:ENOG410PIAF; InterPro:IPR031468,IPR027536; go_component: GO:0032865 - ERMES complex [Evidence IEA]; go_function: GO:0008289 - lipid binding [Evidence IEA]; go_process: GO:0007005 - mitochondrion organization [Evidence IEA] AKAW2_30297S COG:S; EggNog:ENOG410PI15; InterPro:IPR012879; PFAM:PF07946; TransMembrane:1 (o73-92i) AKAW2_30298A COG:P; EggNog:ENOG410PM8K; InterPro:IPR036259,IPR002259; TransMembrane:10 (i45-70o82-103i115-135o141-161i221-243o280-302i314- 331o351-370i382-400o420-443i); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0005337 - nucleoside transmembrane transporter activity [Evidence IEA]; go_process: GO:1901642 - nucleoside transmembrane transport [Evidence IEA] AKAW2_30299A COG:Q; EggNog:ENOG410PG0Y; InterPro:IPR017871,IPR027417,IPR003593,IPR039421, IPR011527,IPR003439,IPR036640; PFAM:PF00005,PF00664; TransMembrane:6 (i177-198o218-240i306-324o330-348i404-426o446-467i); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA]; go_function: GO:0042626 - ATPase-coupled transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_30300S BUSCO:EOG09262SMG; COG:D; EggNog:ENOG410PJFB; InterPro:IPR004918,IPR013874,IPR013873,IPR013855, IPR038189; PFAM:PF08564,PF03234,PF08565; go_function: GO:0019901 - protein kinase binding [Evidence IEA] AKAW2_30301A BUSCO:EOG09264XOC; COG:U; EggNog:ENOG410PN4N; InterPro:IPR000996; PFAM:PF01086; go_component: GO:0030130 - clathrin coat of trans-Golgi network vesicle [Evidence IEA]; go_component: GO:0030132 - clathrin coat of coated pit [Evidence IEA]; go_function: GO:0005198 - structural molecule activity [Evidence IEA]; go_process: GO:0006886 - intracellular protein transport [Evidence IEA]; go_process: GO:0016192 - vesicle-mediated transport [Evidence IEA] AKAW2_30302S COG:A; EggNog:ENOG410PF96; InterPro:IPR006569,IPR008942; PFAM:PF04818 AKAW2_30303A COG:U; EggNog:ENOG410PGG1; InterPro:IPR010989,IPR000727,IPR006012,IPR028673; PFAM:PF05739; TransMembrane:1 (i313-330o); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0031201 - SNARE complex [Evidence IEA]; go_function: GO:0005484 - SNAP receptor activity [Evidence IEA]; go_process: GO:0006886 - intracellular protein transport [Evidence IEA]; go_process: GO:0016192 - vesicle-mediated transport [Evidence IEA] AKAW2_30304S COG:T; EggNog:ENOG410PK2F; InterPro:IPR011992,IPR039030,IPR002048,IPR018247; PFAM:PF00036,PF13499,PF13405,PF08726,PF13202, PF13833; go_function: GO:0005509 - calcium ion binding [Evidence IEA]; go_process: GO:0019722 - calcium-mediated signaling [Evidence IEA] AKAW2_30305A COG:S; EggNog:ENOG410PWNC; InterPro:IPR013921; PFAM:PF08612; go_component: GO:0016592 - mediator complex [Evidence IEA]; go_function: GO:0003712 - transcription coregulator activity [Evidence IEA]; go_process: GO:0006357 - regulation of transcription by RNA polymerase II [Evidence IEA] AKAW2_30306S CAZy:GH47; COG:G; EggNog:ENOG410PG1N; InterPro:IPR036026,IPR012341,IPR001382; PFAM:PF01532; SECRETED:SignalP(1-30); go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0004571 - mannosyl-oligosaccharide 1,2-alpha-mannosidase activity [Evidence IEA]; go_function: GO:0005509 - calcium ion binding [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_30307A COG:S; EggNog:ENOG410PT1N; TransMembrane:7 (o24-47i59-80o108-126i138-159o179-207i219-241o253-272i) AKAW2_30308S COG:E; EggNog:ENOG410PIEB; InterPro:IPR002293; PFAM:PF00324,PF13520; TransMembrane:12 (i57-78o90-109i136-160o180-200i207-228o248-269i290- 313o339-361i381-409o415-441i461-480o492-511i); go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_30309S COG:C; EggNog:ENOG410PHQS; InterPro:IPR003097,IPR001433,IPR017927,IPR001709, IPR023173,IPR017938,IPR039261; PFAM:PF00175,PF00667; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_30310S COG:K; EggNog:ENOG410PRWE; InterPro:IPR008422,IPR001356,IPR009057; PFAM:PF05920,PF00046; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_30312S COG:K; EggNog:ENOG410Q12S; InterPro:IPR036864,IPR001138; PFAM:PF00172; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_30313A CAZy:GH13; COG:G; EggNog:ENOG410PGMM; InterPro:IPR006047,IPR015340,IPR017853,IPR013780, IPR013777; PFAM:PF00128,PF09260; SECRETED:SignalP(1-16); TransMembrane:1 (n4-12c16/17o502-522i); go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0004556 - alpha-amylase activity [Evidence IEA]; go_function: GO:0005509 - calcium ion binding [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA]; go_process: GO:0016052 - carbohydrate catabolic process [Evidence IEA] AKAW2_30314A CAZy:GH31; COG:G; EggNog:ENOG410PHCX; InterPro:IPR000322,IPR017853,IPR011013,IPR013780, IPR030458,IPR030459,IPR031727; PFAM:PF01055,PF16863; SECRETED:SignalP(1-19); go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_function: GO:0030246 - carbohydrate binding [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_30315S COG:K; EggNog:ENOG410PICA; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_30316A COG:S; EggNog:ENOG410PWHW; InterPro:IPR003378; PFAM:PF02434; TransMembrane:1 (i18-36o); go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0016757 - transferase activity, transferring glycosyl groups [Evidence IEA] AKAW2_30317A TransMembrane:1 (i63-85o) AKAW2_30318S COG:U; EggNog:ENOG410PIXS; InterPro:IPR013699,IPR011990,IPR031545,IPR026270; PFAM:PF17004,PF08492; go_component: GO:0048500 - signal recognition particle [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_function: GO:0008312 - 7S RNA binding [Evidence IEA]; go_process: GO:0006614 - SRP-dependent cotranslational protein targeting to membrane [Evidence IEA] AKAW2_30319A COG:S; EggNog:ENOG410PUMI; InterPro:IPR036291,IPR000683; PFAM:PF01408; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA] AKAW2_30320S COG:S; EggNog:ENOG410PK4Y; InterPro:IPR002035,IPR036465 AKAW2_30321A COG:S; EggNog:ENOG410PFS8; InterPro:IPR036188,IPR006905 AKAW2_30322S COG:P; EggNog:ENOG410PHPX; InterPro:IPR018303,IPR023298,IPR023299,IPR001757, IPR032630,IPR006539,IPR036412,IPR008250,IPR023214, IPR032631; PFAM:PF13246,PF00122,PF16209,PF00702,PF16212; TransMembrane:10 (i343-360o366-385i583-605o617-637i644-661o1356-1376i1406- 1428o1440-1457i1469-1488o1516-1536i); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0000166 - nucleotide binding [Evidence IEA]; go_function: GO:0000287 - magnesium ion binding [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0140326 - ATPase-coupled intramembrane lipid transporter activity [Evidence IEA]; go_process: GO:0015914 - phospholipid transport [Evidence IEA] AKAW2_30323S COG:S; EggNog:ENOG410PTIR AKAW2_30324S COG:S; EggNog:ENOG410PXFF; TransMembrane:11 (o28-48i106-128o140-163i175-196o228-248i316-335o355- 376i441-461o481-501i513-537o543-567i) AKAW2_30325A COG:S; EggNog:ENOG410PSKF; InterPro:IPR036020,IPR001202; PFAM:PF00397; TransMembrane:1 (i165-183o); go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_30326S CAZy:GT71; COG:G; EggNog:ENOG410PHW7; InterPro:IPR022751,IPR029044; PFAM:PF11051; go_function: GO:0016757 - transferase activity, transferring glycosyl groups [Evidence IEA]; go_process: GO:0006486 - protein glycosylation [Evidence IEA] AKAW2_30327S COG:K; EggNog:ENOG410PJTV; InterPro:IPR017970,IPR001356,IPR009057; PFAM:PF00046; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_30328A BUSCO:EOG09264S4C; COG:S; EggNog:ENOG410PNB1; InterPro:IPR010021,IPR027706,IPR036412,IPR023214; PFAM:PF13242,PF09419; go_function: GO:0008962 - phosphatidylglycerophosphatase activity [Evidence IEA] AKAW2_30329S COG:A; EggNog:ENOG410PP13; InterPro:IPR034099,IPR027141,IPR010920,IPR001163; PFAM:PF01423; go_component: GO:0005681 - spliceosomal complex [Evidence IEA]; go_process: GO:0000387 - spliceosomal snRNP assembly [Evidence IEA]; go_process: GO:0006396 - RNA processing [Evidence IEA] AKAW2_30330S COG:S; EggNog:ENOG410PQ1Y; InterPro:IPR034627; PFAM:PF10199; go_process: GO:0016192 - vesicle-mediated transport [Evidence IEA] AKAW2_30331A COG:I; EggNog:ENOG410PPRW; InterPro:IPR007482; PFAM:PF04387; TransMembrane:6 (i7-32o44-64i71-92o104-122i129-146o180-200i) AKAW2_30332A COG:S; EggNog:ENOG410PHM2; InterPro:IPR001138; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_30334S COG:O; EggNog:ENOG410PJMU; InterPro:IPR001330,IPR026872,IPR008930; PFAM:PF00432; go_component: GO:0005965 - protein farnesyltransferase complex [Evidence IEA]; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_process: GO:0018343 - protein farnesylation [Evidence IEA] AKAW2_30335S COG:S; EggNog:ENOG410PXG3; InterPro:IPR014720; PFAM:PF00035 AKAW2_30336S COG:S; EggNog:ENOG410PJM8; InterPro:IPR006769,IPR039055; PFAM:PF04678; TransMembrane:2 (i340-360o372-390i); go_process: GO:0051560 - mitochondrial calcium ion homeostasis [Evidence IEA] AKAW2_30337A COG:S; EggNog:ENOG410PXCW AKAW2_30338A BUSCO:EOG09265DDU; COG:T; EggNog:ENOG410PQMZ; InterPro:IPR008207,IPR036641; PFAM:PF01627; go_process: GO:0000160 - phosphorelay signal transduction system [Evidence IEA] AKAW2_30340A COG:S; EggNog:ENOG410PN33; InterPro:IPR036236,IPR022755,IPR013087; PFAM:PF13912,PF12171,PF12874 AKAW2_30341S BUSCO:EOG092614ZG; COG:O; EggNog:ENOG410PH2Q; InterPro:IPR001841,IPR001607,IPR034931,IPR011422, IPR013083; PFAM:PF07576,PF13639,PF02148; go_function: GO:0008270 - zinc ion binding [Evidence IEA] AKAW2_30342A BUSCO:EOG09263SZM; COG:H; EggNog:ENOG410PG9Z; InterPro:IPR029063,IPR010233; PFAM:PF13649,PF13489,PF08242,PF08241,PF13847; go_function: GO:0008425 - 2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity [Evidence IEA]; go_process: GO:0006744 - ubiquinone biosynthetic process [Evidence IEA] AKAW2_30343S COG:K; EggNog:ENOG410PG1H; InterPro:IPR036236,IPR013087; PFAM:PF00096 AKAW2_30344A COG:S; EggNog:ENOG410PG42; InterPro:IPR003734; PFAM:PF02582; TransMembrane:1 (o584-603i) AKAW2_30345A COG:S; EggNog:ENOG410PJM6; InterPro:IPR039164; go_function: GO:0061630 - ubiquitin protein ligase activity [Evidence IEA]; go_process: GO:0071596 - ubiquitin-dependent protein catabolic process via the N-end rule pathway [Evidence IEA] AKAW2_30346A COG:E; EggNog:ENOG410Q89J; InterPro:IPR004839,IPR004838,IPR000796,IPR015424, IPR015421,IPR015422; PFAM:PF00155; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0008483 - transaminase activity [Evidence IEA]; go_function: GO:0030170 - pyridoxal phosphate binding [Evidence IEA]; go_process: GO:0006520 - cellular amino acid metabolic process [Evidence IEA]; go_process: GO:0009058 - biosynthetic process [Evidence IEA] AKAW2_30347A BUSCO:EOG0926534P; COG:A; EggNog:ENOG410PKBF; InterPro:IPR005011; PFAM:PF03343; go_process: GO:0000398 - mRNA splicing, via spliceosome [Evidence IEA] AKAW2_30348A COG:S; EggNog:ENOG410PNRQ; InterPro:IPR023476,IPR002833; PFAM:PF01981; TransMembrane:1 (o12-30i); go_function: GO:0004045 - aminoacyl-tRNA hydrolase activity [Evidence IEA] AKAW2_30349A COG:S; EggNog:ENOG410PPAG; SECRETED:SignalP(1-16); TransMembrane:1 (n3-10c16/17o216-236i) AKAW2_30351S COG:G; EggNog:ENOG410PFDZ; InterPro:IPR017926,IPR032466,IPR036901,IPR035686, IPR036480,IPR036914,IPR002082,IPR005479,IPR006132, IPR006130,IPR006131,IPR006275,IPR006274,IPR036897, IPR013815,IPR011607,IPR011761,IPR016185,IPR029062, IPR002474,IPR005483,IPR005480; MEROPS:MER0060647; PFAM:PF00117,PF00988,PF02222,PF00185,PF02787, PF02786,PF02142,PF07478,PF02729; go_function: GO:0004070 - aspartate carbamoyltransferase activity [Evidence IEA]; go_function: GO:0004088 - carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016597 - amino acid binding [Evidence IEA]; go_function: GO:0016743 - carboxyl- or carbamoyltransferase activity [Evidence IEA]; go_function: GO:0046872 - metal ion binding [Evidence IEA]; go_process: GO:0006207 - 'de novo' pyrimidine nucleobase biosynthetic process [Evidence IEA]; go_process: GO:0006520 - cellular amino acid metabolic process [Evidence IEA]; go_process: GO:0006541 - glutamine metabolic process [Evidence IEA]; go_process: GO:0006807 - nitrogen compound metabolic process [Evidence IEA] AKAW2_30352A CAZy:CE10; COG:V; EggNog:ENOG410PWZP; InterPro:IPR029058,IPR013094; MEROPS:MER0043003; PFAM:PF07859; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_30353A COG:I; EggNog:ENOG410PKQX; InterPro:IPR000873,IPR020845,IPR042099,IPR025110; PFAM:PF00501,PF13193 AKAW2_30354A COG:U; EggNog:ENOG410PI5R; InterPro:IPR042561,IPR042560,IPR011993,IPR016159, IPR032403,IPR033961; PFAM:PF08700,PF16528; go_component: GO:0000145 - exocyst [Evidence IEA]; go_process: GO:0006887 - exocytosis [Evidence IEA] AKAW2_30355S COG:U; EggNog:ENOG410PPYB; InterPro:IPR023392,IPR002056; PFAM:PF02064; go_component: GO:0005742 - mitochondrial outer membrane translocase complex [Evidence IEA]; go_process: GO:0006605 - protein targeting [Evidence IEA]; go_process: GO:0006886 - intracellular protein transport [Evidence IEA] AKAW2_30356S CAZy:GH72; COG:S; EggNog:ENOG410PFIQ; InterPro:IPR017853,IPR004886; PFAM:PF03198; SECRETED:SignalP(1-21); TransMembrane:1 (n8-16c21/22o466-485i) AKAW2_30357A COG:S; EggNog:ENOG410PJU2; InterPro:IPR001810,IPR036322,IPR015943,IPR036047, IPR003903; PFAM:PF00646,PF12937; TransMembrane:2 (o365-383i395-413o); go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_30358S BUSCO:EOG09262GVX; COG:L; EggNog:ENOG410PG13; InterPro:IPR003701,IPR029052,IPR041796,IPR038487, IPR007281,IPR004843; PFAM:PF00149,PF04152; go_component: GO:0005634 - nucleus [Evidence IEA]; go_component: GO:0030870 - Mre11 complex [Evidence IEA]; go_function: GO:0004519 - endonuclease activity [Evidence IEA]; go_function: GO:0008408 - 3'-5' exonuclease activity [Evidence IEA]; go_function: GO:0016787 - hydrolase activity [Evidence IEA]; go_function: GO:0030145 - manganese ion binding [Evidence IEA]; go_process: GO:0006302 - double-strand break repair [Evidence IEA] AKAW2_30359A COG:S; EggNog:ENOG410PJDF; InterPro:IPR010839; PFAM:PF07287 AKAW2_30360A COG:S; EggNog:ENOG410PNSD; InterPro:IPR011576,IPR012349; PFAM:PF01243; TransMembrane:1 (i224-244o) AKAW2_30361S COG:C; EggNog:ENOG410PFKN; InterPro:IPR015590,IPR029510,IPR016160,IPR016161, IPR016162,IPR016163; PFAM:PF00171; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0016620 - oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_30362A COG:E; EggNog:ENOG410PJ40; InterPro:IPR017439,IPR017144,IPR036264,IPR011650; MEROPS:MER0014418; PFAM:PF07687; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_30363S COG:S; EggNog:ENOG410PP8D; InterPro:IPR032805; PFAM:PF13813; TransMembrane:8 (i7-26o32-52i137-160o189-208i282-305o311-329i349-372o392- 415i) AKAW2_30364S COG:S; EggNog:ENOG410PT59 AKAW2_30365S COG:S; EggNog:ENOG410PNB9; InterPro:IPR012349,IPR038725; PFAM:PF01243,PF16242 AKAW2_30366A COG:K; EggNog:ENOG410PHPH; InterPro:IPR009072,IPR003195; PFAM:PF02269; go_function: GO:0046982 - protein heterodimerization activity [Evidence IEA]; go_process: GO:0006366 - transcription by RNA polymerase II [Evidence IEA] AKAW2_30367S BUSCO:EOG09263JW5; COG:J; EggNog:ENOG410PGKF; InterPro:IPR035996,IPR014777,IPR000878,IPR014776, IPR004551; PFAM:PF00590; go_function: GO:0004164 - diphthine synthase activity [Evidence IEA]; go_function: GO:0008168 - methyltransferase activity [Evidence IEA]; go_process: GO:0017183 - peptidyl-diphthamide biosynthetic process from peptidyl-histidine [Evidence IEA] AKAW2_30368A COG:S; EggNog:ENOG410PPF2 AKAW2_30369S COG:U; EggNog:ENOG410PMYN; InterPro:IPR016635,IPR022775,IPR011012,IPR027156; PFAM:PF01217; go_component: GO:0030122 - AP-2 adaptor complex [Evidence IEA]; go_function: GO:0035615 - clathrin adaptor activity [Evidence IEA]; go_process: GO:0015031 - protein transport [Evidence IEA]; go_process: GO:0016192 - vesicle-mediated transport [Evidence IEA]; go_process: GO:0072583 - clathrin-dependent endocytosis [Evidence IEA] AKAW2_30371S COG:S; EggNog:ENOG410PFKR; InterPro:IPR040632,IPR027417; PFAM:PF17784; TransMembrane:1 (o258-280i) AKAW2_30372S COG:S; EggNog:ENOG410PK7H; InterPro:IPR039535; PFAM:PF05935,PF14269; SECRETED:SignalP(1-33); TransMembrane:1 (n17-28c33/34o588-609i) AKAW2_30373S COG:P; EggNog:ENOG410PHRS; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:11 (i177-200o220-237i249-269o275-296i308-331o361-383i469- 493o513-540i560-579o591-610i666-686o); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_30374A BUSCO:EOG09264PK5; COG:Z; EggNog:ENOG410PJI2; InterPro:IPR005061,IPR042277; go_process: GO:0015031 - protein transport [Evidence IEA] AKAW2_30375A CAZy:GH132; COG:S; EggNog:ENOG410PG80; InterPro:IPR005556; PFAM:PF03856; SECRETED:SignalP(1-18) AKAW2_30376A COG:O; EggNog:ENOG410PKRD; InterPro:IPR007213,IPR029063,IPR016651; PFAM:PF04072; go_function: GO:0008168 - methyltransferase activity [Evidence IEA]; go_process: GO:0032259 - methylation [Evidence IEA] AKAW2_30377S SECRETED:SignalP(1-19) AKAW2_30378A COG:O; EggNog:ENOG410PGEB; InterPro:IPR016024,IPR001841,IPR011016,IPR039804, IPR039795,IPR013083; PFAM:PF11793,PF13639; go_component: GO:1990112 - RQC complex [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_function: GO:0061630 - ubiquitin protein ligase activity [Evidence IEA]; go_process: GO:1990116 - ribosome-associated ubiquitin-dependent protein catabolic process [Evidence IEA] AKAW2_30379S BUSCO:EOG09260ZWU; COG:L; EggNog:ENOG410PGIM; InterPro:IPR010643,IPR013020,IPR027417,IPR006554, IPR006555,IPR014013,IPR010614,IPR001945; PFAM:PF06777,PF13307,PF06733; go_component: GO:0005634 - nucleus [Evidence IEA]; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0003678 - DNA helicase activity [Evidence IEA]; go_function: GO:0004386 - helicase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016818 - hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [Evidence IEA]; go_process: GO:0006139 - nucleobase-containing compound metabolic process [Evidence IEA]; go_process: GO:0006289 - nucleotide-excision repair [Evidence IEA] AKAW2_30380A BUSCO:EOG092605OK; COG:K; EggNog:ENOG410PG11; InterPro:IPR007066,IPR007081,IPR007080,IPR007083, IPR038120,IPR000722,IPR042102,IPR006592,IPR015699; PFAM:PF05000,PF04998,PF04997,PF04983,PF00623; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0003899 - DNA-directed 5'-3' RNA polymerase activity [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA] AKAW2_30381S BUSCO:EOG092621ZV; COG:A; EggNog:ENOG410PFS0; InterPro:IPR010541,IPR027104,IPR013881; PFAM:PF06544,PF08572; go_component: GO:0046540 - U4/U6 x U5 tri-snRNP complex [Evidence IEA]; go_process: GO:0000398 - mRNA splicing, via spliceosome [Evidence IEA] AKAW2_30382A BUSCO:EOG09263G4R; COG:S; EggNog:ENOG410PM0K; InterPro:IPR007504,IPR009000,IPR040309,IPR038664; PFAM:PF04410; go_component: GO:0005732 - small nucleolar ribonucleoprotein complex [Evidence IEA]; go_function: GO:0003723 - RNA binding [Evidence IEA]; go_process: GO:0000493 - box H/ACA snoRNP assembly [Evidence IEA]; go_process: GO:0001522 - pseudouridine synthesis [Evidence IEA]; go_process: GO:0042254 - ribosome biogenesis [Evidence IEA] AKAW2_30383S BUSCO:EOG09261FM4; CAZy:GT22; COG:G; EggNog:ENOG410PIIT; InterPro:IPR039484,IPR005599; PFAM:PF03901; TransMembrane:10 (i32-56o117-135i142-161o167-185i197-220o232-256i299- 321o333-352i364-383o403-426i); go_function: GO:0000030 - mannosyltransferase activity [Evidence IEA]; go_function: GO:0016757 - transferase activity, transferring glycosyl groups [Evidence IEA] AKAW2_30384S COG:S; EggNog:ENOG410PFBI; InterPro:IPR021848; PFAM:PF11927; TransMembrane:2 (i12-37o221-237i) AKAW2_30385A COG:S; EggNog:ENOG410PKNI; InterPro:IPR019190; PFAM:PF09810; go_function: GO:0045145 - single-stranded DNA 5'-3' exodeoxyribonuclease activity [Evidence IEA] AKAW2_30386A COG:S; EggNog:ENOG410PWQ1; InterPro:IPR007248; PFAM:PF04117; go_component: GO:0016021 - integral component of membrane [Evidence IEA] AKAW2_30387A COG:G; EggNog:ENOG410PFTW; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i73-90o110-129i141-160o166-188i200-223o229-258i306- 325o345-363i384-404o410-431i443-463o475-497i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_30388A COG:B; EggNog:ENOG410Q7WQ; InterPro:IPR007125,IPR009072,IPR000164; PFAM:PF00125; go_component: GO:0000786 - nucleosome [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0046982 - protein heterodimerization activity [Evidence IEA] AKAW2_30389S COG:B; EggNog:ENOG410PPJQ; InterPro:IPR004823,IPR009072,IPR019809,IPR001951, IPR035425; PFAM:PF02969,PF15511; go_component: GO:0000786 - nucleosome [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0046982 - protein heterodimerization activity [Evidence IEA]; go_process: GO:0006352 - DNA-templated transcription, initiation [Evidence IEA] AKAW2_30390A COG:Q; EggNog:ENOG410PJA1; InterPro:IPR009081,IPR006162,IPR036736,IPR036291, IPR020806,IPR013968; PFAM:PF00550,PF08659; go_function: GO:0031177 - phosphopantetheine binding [Evidence IEA] AKAW2_30391A COG:Q; EggNog:ENOG410PFKE; InterPro:IPR011032,IPR020843,IPR036291; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA] AKAW2_30392A COG:Q; EggNog:ENOG410PJA1; InterPro:IPR013217,IPR029063; PFAM:PF08242,PF13649 AKAW2_30393A COG:Q; EggNog:ENOG410PJA1; InterPro:IPR001227,IPR016036,IPR014043,IPR016035; PFAM:PF00698; go_function: GO:0016740 - transferase activity [Evidence IEA] AKAW2_30394S COG:I; EggNog:ENOG410PMPI; InterPro:IPR009081,IPR029063,IPR036736,IPR029058, IPR013217,IPR020806,IPR041068,IPR042104,IPR020807; PFAM:PF13649,PF13489,PF08242,PF00550,PF14765, PF18558; go_function: GO:0031177 - phosphopantetheine binding [Evidence IEA] AKAW2_30395A COG:K; EggNog:ENOG410PISR; InterPro:IPR036236,IPR013087; PFAM:PF00096 AKAW2_30397S TransMembrane:1 (o30-47i) AKAW2_30398A COG:H; EggNog:ENOG410Q5HU; InterPro:IPR016037,IPR013792,IPR008289,IPR010110, IPR041121,IPR013785,IPR023193,IPR001381,IPR027417, IPR013708,IPR018508,IPR030960,IPR001986,IPR023000, IPR036968,IPR036291,IPR000623,IPR006264,IPR031322; PFAM:PF01761,PF08501,PF00275,PF01487,PF13685, PF01202,PF18317; go_component: GO:0005737 - cytoplasm [Evidence IEA]; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0003855 - 3-dehydroquinate dehydratase activity [Evidence IEA]; go_function: GO:0003856 - 3-dehydroquinate synthase activity [Evidence IEA]; go_function: GO:0003866 - 3-phosphoshikimate 1-carboxyvinyltransferase activity [Evidence IEA]; go_function: GO:0004764 - shikimate 3-dehydrogenase (NADP+) activity [Evidence IEA]; go_function: GO:0004765 - shikimate kinase activity [Evidence IEA]; go_function: GO:0016765 - transferase activity, transferring alkyl or aryl (other than methyl) groups [Evidence IEA]; go_process: GO:0009073 - aromatic amino acid family biosynthetic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_30399A COG:K; EggNog:ENOG410PGM5; InterPro:IPR027073,IPR017151,IPR001878,IPR041412, IPR004859; PFAM:PF17846,PF03159; go_component: GO:0005634 - nucleus [Evidence IEA]; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0004527 - exonuclease activity [Evidence IEA]; go_function: GO:0004534 - 5'-3' exoribonuclease activity [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006139 - nucleobase-containing compound metabolic process [Evidence IEA] AKAW2_30400S BUSCO:EOG09261B18; COG:U; EggNog:ENOG410PIP4; InterPro:IPR016024,IPR011989,IPR006953,IPR006955; PFAM:PF04871,PF04869; TransMembrane:1 (o554-574i); go_component: GO:0000139 - Golgi membrane [Evidence IEA]; go_component: GO:0005737 - cytoplasm [Evidence IEA]; go_process: GO:0006886 - intracellular protein transport [Evidence IEA]; go_process: GO:0016192 - vesicle-mediated transport [Evidence IEA]; go_process: GO:0048280 - vesicle fusion with Golgi apparatus [Evidence IEA] AKAW2_30401S BUSCO:EOG0926092K; COG:J; EggNog:ENOG410PGN9; InterPro:IPR013155,IPR023586,IPR033709,IPR009080, IPR001412,IPR014729,IPR009008,IPR002301,IPR002300; PFAM:PF00133,PF08264; go_function: GO:0000049 - tRNA binding [Evidence IEA]; go_function: GO:0000166 - nucleotide binding [Evidence IEA]; go_function: GO:0002161 - aminoacyl-tRNA editing activity [Evidence IEA]; go_function: GO:0004812 - aminoacyl-tRNA ligase activity [Evidence IEA]; go_function: GO:0004822 - isoleucine-tRNA ligase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006418 - tRNA aminoacylation for protein translation [Evidence IEA]; go_process: GO:0006428 - isoleucyl-tRNA aminoacylation [Evidence IEA] AKAW2_30402A COG:S; EggNog:ENOG410PSVJ; InterPro:IPR034595; go_component: GO:0005739 - mitochondrion [Evidence IEA]; go_process: GO:0032981 - mitochondrial respiratory chain complex I assembly [Evidence IEA] AKAW2_30403S COG:S; EggNog:ENOG410PMNV; InterPro:IPR013665; PFAM:PF08457 AKAW2_30404A COG:S; EggNog:ENOG410PW56; InterPro:IPR011009,IPR002575; PFAM:PF01636 AKAW2_30405S BUSCO:EOG09260A6Q; COG:S; EggNog:ENOG410PID2; InterPro:IPR015943,IPR001680,IPR022033,IPR036322; PFAM:PF12234; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_30406A SECRETED:SignalP(1-23) AKAW2_30407A COG:S; EggNog:ENOG410Q2KE; SECRETED:SignalP(1-20) AKAW2_30409S COG:C,H; EggNog:ENOG410Q22K; InterPro:IPR036188,IPR002938,IPR036249,IPR038220, IPR012941; PFAM:PF07976,PF01494; go_function: GO:0071949 - FAD binding [Evidence IEA] AKAW2_30410S COG:C; EggNog:ENOG410QEBP; InterPro:IPR006140,IPR036291,IPR006139; PFAM:PF03807,PF00389,PF02826; go_function: GO:0016616 - oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Evidence IEA]; go_function: GO:0051287 - NAD binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_30411S COG:P; EggNog:ENOG410PHAB; InterPro:IPR004813; PFAM:PF03169; TransMembrane:14 (i60-77o83-103i115-138o171-189i278-296o302-324i336- 353o373-395i478-497o503-524i596-617o651-672i692-723o781- 802i); go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_30412A COG:T; EggNog:ENOG410PRID; InterPro:IPR001452,IPR036028; PFAM:PF07653,PF00018,PF14604; TransMembrane:1 (o191-212i); go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_30413A COG:T; EggNog:ENOG410PMUT; InterPro:IPR036546,IPR008271,IPR036529,IPR000719, IPR011009; PFAM:PF16987,PF07714,PF00069; go_function: GO:0003712 - transcription coregulator activity [Evidence IEA]; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_30414S COG:S; EggNog:ENOG410PG01; InterPro:IPR001060,IPR027267,IPR018808,IPR028565; PFAM:PF00611,PF10291 AKAW2_30415A BUSCO:EOG092630UB; COG:D; EggNog:ENOG410PKQ7; InterPro:IPR008672; PFAM:PF05557; go_process: GO:0007094 - mitotic spindle assembly checkpoint [Evidence IEA] AKAW2_30416S COG:J; EggNog:ENOG410PQ50; InterPro:IPR004038,IPR029064,IPR004037; PFAM:PF01248; go_component: GO:1990904 - ribonucleoprotein complex [Evidence IEA]; go_process: GO:0042254 - ribosome biogenesis [Evidence IEA] AKAW2_30417S BUSCO:EOG09262GLP; CAZy:GT76; COG:G; EggNog:ENOG410PH12; InterPro:IPR007315; PFAM:PF04188; SECRETED:SignalP(1-38); TransMembrane:9 (o12-33i93-117o123-144i156-175o181-199i258-278o324- 345i381-400o438-461i); go_function: GO:0000009 - alpha-1,6-mannosyltransferase activity [Evidence IEA]; go_function: GO:0004376 - glycolipid mannosyltransferase activity [Evidence IEA]; go_process: GO:0006506 - GPI anchor biosynthetic process [Evidence IEA] AKAW2_30418A COG:S; EggNog:ENOG410PQM1 AKAW2_30419A COG:S; EggNog:ENOG410PTME AKAW2_30420S COG:J; EggNog:ENOG410PFRY; InterPro:IPR012675,IPR027417,IPR006073,IPR031167, IPR013646; PFAM:PF08438,PF01926; go_function: GO:0005525 - GTP binding [Evidence IEA] AKAW2_30421A COG:S; EggNog:ENOG410PZ7C AKAW2_30422S COG:S; EggNog:ENOG410QE4S AKAW2_30424S COG:K; EggNog:ENOG410PFI7; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_30425S COG:G; EggNog:ENOG410PGGV; InterPro:IPR020826,IPR029061,IPR005478,IPR033248, IPR033247,IPR009014,IPR005474,IPR005475; PFAM:PF02779,PF02780,PF00456; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0004802 - transketolase activity [Evidence IEA] AKAW2_30426A COG:E; EggNog:ENOG410PHI1; InterPro:IPR030373,IPR030374,IPR029063,IPR001045, IPR035246,IPR030668,IPR037163; PFAM:PF01564,PF17284; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_process: GO:0006595 - polyamine metabolic process [Evidence IEA] AKAW2_30427A COG:C; EggNog:ENOG410PR2K; InterPro:IPR004205,IPR036642; PFAM:PF02939; TransMembrane:1 (i59-77o); go_function: GO:0008121 - ubiquinol-cytochrome-c reductase activity [Evidence IEA] AKAW2_30428S COG:O; EggNog:ENOG410PFZQ; InterPro:IPR001107,IPR000163,IPR036013; PFAM:PF01145; go_component: GO:0016020 - membrane [Evidence IEA] AKAW2_30429A COG:S; EggNog:ENOG410PHDI; InterPro:IPR021463; PFAM:PF11312 AKAW2_30430A COG:S; EggNog:ENOG410PM11 AKAW2_30431A antiSMASH:Cluster_3.1 AKAW2_30432S COG:O; EggNog:ENOG410PFUQ; InterPro:IPR043170,IPR004327,IPR037218; PFAM:PF03095; antiSMASH:Cluster_3.1; go_function: GO:0019211 - phosphatase activator activity [Evidence IEA] AKAW2_30433S COG:S; EggNog:ENOG410PSJR; InterPro:IPR013865; PFAM:PF08555; antiSMASH:Cluster_3.1 AKAW2_30434S antiSMASH:Cluster_3.1 AKAW2_30435A COG:S; EggNog:ENOG410PUHF; InterPro:IPR001077,IPR036388,IPR016461,IPR029063, IPR036390; PFAM:PF00891; SMCOG1042:O-methyltransferase; antiSMASH:Cluster_3.1; go_function: GO:0008168 - methyltransferase activity [Evidence IEA]; go_function: GO:0008171 - O-methyltransferase activity [Evidence IEA] AKAW2_30436A COG:Q; EggNog:ENOG410Q24T; InterPro:IPR001128,IPR017972,IPR002401,IPR036396; PFAM:PF00067; SMCOG1034:cytochrome P450; antiSMASH:Cluster_3.1; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_30437S COG:I; EggNog:ENOG410PG86; InterPro:IPR016036,IPR032088,IPR016035,IPR009081, IPR030918,IPR001227,IPR014043,IPR036736,IPR016039, IPR018201,IPR020807,IPR042104,IPR014030,IPR014031, IPR020841; PFAM:PF14765,PF00109,PF16073,PF02801,PF00698, PF00550; SMCOG1022:Beta-ketoacyl synthase; antiSMASH:Cluster_3.1; go_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein] synthase activity [Evidence IEA]; go_function: GO:0016740 - transferase activity [Evidence IEA]; go_function: GO:0016746 - transferase activity, transferring acyl groups [Evidence IEA]; go_process: GO:0006633 - fatty acid biosynthetic process [Evidence IEA] AKAW2_30438A COG:G; EggNog:ENOG410PFF2; InterPro:IPR036259; TransMembrane:4 (i47-66o72-98i110-131o137-159i); antiSMASH:Cluster_3.1 AKAW2_30439A COG:G; EggNog:ENOG410PFF2; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; SMCOG1005:Drug resistance transporter, EmrB/QacA; TransMembrane:8 (i49-70o85-105i117-134o140-163i175-200o206-224i294- 317o329-351i); antiSMASH:Cluster_3.1; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_30440S COG:S; EggNog:ENOG410PNAW; InterPro:IPR011009,IPR002575,IPR008266; PFAM:PF01636; TransMembrane:1 (o321-345i); antiSMASH:Cluster_3.1; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_30441S COG:S; EggNog:ENOG410Q246; antiSMASH:Cluster_3.1 AKAW2_30442S COG:S; EggNog:ENOG410Q246; InterPro:IPR029063,IPR016461,IPR001077; antiSMASH:Cluster_3.1; go_function: GO:0008168 - methyltransferase activity [Evidence IEA]; go_function: GO:0008171 - O-methyltransferase activity [Evidence IEA] AKAW2_30443A COG:Z; EggNog:ENOG410PFDU; InterPro:IPR023123,IPR002454,IPR008280,IPR036525, IPR037103,IPR000217,IPR018316,IPR003008,IPR017975; PFAM:PF03953; antiSMASH:Cluster_3.1; go_component: GO:0000930 - gamma-tubulin complex [Evidence IEA]; go_component: GO:0005874 - microtubule [Evidence IEA]; go_function: GO:0003924 - GTPase activity [Evidence IEA]; go_function: GO:0005525 - GTP binding [Evidence IEA]; go_process: GO:0007017 - microtubule-based process [Evidence IEA]; go_process: GO:0007020 - microtubule nucleation [Evidence IEA]; go_process: GO:0031122 - cytoplasmic microtubule organization [Evidence IEA] AKAW2_30444A COG:E; EggNog:ENOG410PPX2; InterPro:IPR015942; PFAM:PF01177; antiSMASH:Cluster_3.1; go_function: GO:0036361 - racemase activity, acting on amino acids and derivatives [Evidence IEA]; go_process: GO:0006807 - nitrogen compound metabolic process [Evidence IEA] AKAW2_30445S COG:C; EggNog:ENOG410PM5J; InterPro:IPR020471,IPR036812,IPR023210; PFAM:PF00248; SMCOG1039:aldo/keto reductase family oxidoreductase; antiSMASH:Cluster_3.1; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_30446S COG:G; EggNog:ENOG410QDJB; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; SMCOG1106:major facilitator transporter; TransMembrane:10 (i187-205o217-236i248-268o280-301i362-382o394-414i421- 441o453-475i487-508o520-541i); antiSMASH:Cluster_3.1; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_30447S COG:S; EggNog:ENOG410PJMY; InterPro:IPR031581,IPR026505; PFAM:PF16965,PF00892; SMCOG1166:transporter, EamA family; TransMembrane:10 (i70-94o106-125i171-192o204-222i229-246o270-286i307- 326o346-367i374-393o399-422i); antiSMASH:Cluster_3.1; go_component: GO:0030176 - integral component of endoplasmic reticulum membrane [Evidence IEA]; go_function: GO:0030234 - enzyme regulator activity [Evidence IEA]; go_process: GO:0006874 - cellular calcium ion homeostasis [Evidence IEA] AKAW2_30448A BUSCO:EOG09262MEK; COG:Z; EggNog:ENOG410PH2T; InterPro:IPR020902,IPR004000,IPR043129; PFAM:PF00022 AKAW2_30449S COG:I; EggNog:ENOG410PKCT; InterPro:IPR029154,IPR015815,IPR036291,IPR006115, IPR008927,IPR013328; PFAM:PF03446,PF14833; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0050661 - NADP binding [Evidence IEA]; go_function: GO:0051287 - NAD binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_30450A COG:S; EggNog:ENOG410PIKQ; InterPro:IPR021833; PFAM:PF11905 AKAW2_30451A BUSCO:EOG09261UWT; COG:H; EggNog:ENOG410PG5G; InterPro:IPR036144,IPR032677,IPR000926; PFAM:PF00925; go_function: GO:0003935 - GTP cyclohydrolase II activity [Evidence IEA]; go_process: GO:0009231 - riboflavin biosynthetic process [Evidence IEA] AKAW2_30452A BUSCO:EOG09263817; COG:S; EggNog:ENOG410PK50; InterPro:IPR010750,IPR037802; PFAM:PF07039; go_component: GO:0000124 - SAGA complex [Evidence IEA] AKAW2_30453S COG:G; EggNog:ENOG410PFMA; InterPro:IPR018050,IPR016305,IPR014710,IPR001250, IPR011051; PFAM:PF01238; go_function: GO:0004476 - mannose-6-phosphate isomerase activity [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA]; go_process: GO:0009298 - GDP-mannose biosynthetic process [Evidence IEA] AKAW2_30454S CAZy:CE10; COG:I; EggNog:ENOG410PMK8; InterPro:IPR029058,IPR013094; MEROPS:MER0033242; PFAM:PF10340,PF07859; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_30455A COG:U; EggNog:ENOG410PJM1; InterPro:IPR011990,IPR006822; PFAM:PF04733,PF13432,PF13174; go_function: GO:0005198 - structural molecule activity [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0006890 - retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [Evidence IEA] AKAW2_30456A BUSCO:EOG09260GIX; COG:I; EggNog:ENOG410PJKK; InterPro:IPR000008,IPR037755,IPR011992,IPR001192, IPR011993,IPR017946,IPR035892,IPR000909,IPR002048, IPR001711; PFAM:PF00387,PF00388; go_function: GO:0004435 - phosphatidylinositol phospholipase C activity [Evidence IEA]; go_function: GO:0005509 - calcium ion binding [Evidence IEA]; go_function: GO:0008081 - phosphoric diester hydrolase activity [Evidence IEA]; go_process: GO:0006629 - lipid metabolic process [Evidence IEA]; go_process: GO:0007165 - signal transduction [Evidence IEA]; go_process: GO:0035556 - intracellular signal transduction [Evidence IEA] AKAW2_30459S COG:F; EggNog:ENOG410PHW9; InterPro:IPR001365,IPR032466; PFAM:PF00962; go_function: GO:0019239 - deaminase activity [Evidence IEA] AKAW2_30460A COG:S; EggNog:ENOG410PK37 AKAW2_30461A COG:Q; EggNog:ENOG410Q1ZS; InterPro:IPR001128,IPR017972,IPR036396; PFAM:PF00067; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_30462A COG:F,H; EggNog:ENOG410PHPC; InterPro:IPR038271,IPR012681,IPR001248; PFAM:PF02133; TransMembrane:12 (i43-62o74-93i100-123o173-191i198-218o238-258i279-308o328- 348i369-386o398-418i448-470o476-496i); go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_30463A COG:S; EggNog:ENOG410PRR1; InterPro:IPR018849; PFAM:PF10441 AKAW2_30464S BUSCO:EOG09265PQX; COG:S; EggNog:ENOG410PQM9; InterPro:IPR007512; PFAM:PF04418; TransMembrane:1 (o36-55i); go_component: GO:0005743 - mitochondrial inner membrane [Evidence IEA]; go_component: GO:0061617 - MICOS complex [Evidence IEA] AKAW2_30465A COG:S; EggNog:ENOG410PS90; InterPro:IPR036395,IPR001083; antiSMASH:Cluster_3.2; go_component: GO:0005634 - nucleus [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0003700 - DNA-binding transcription factor activity [Evidence IEA]; go_function: GO:0005507 - copper ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_30466S COG:S; EggNog:ENOG410PNDK; InterPro:IPR012336,IPR033468,IPR021211; PFAM:PF10568,PF17171,PF17172; antiSMASH:Cluster_3.2 AKAW2_30467A COG:S; EggNog:ENOG410PX69; TransMembrane:7 (o18-41i53-78o98-122i134-152o177-201i213-233o253-272i); antiSMASH:Cluster_3.2 AKAW2_30468S CAZy:AA7; COG:C; EggNog:ENOG410PGWT; InterPro:IPR016166,IPR006094,IPR036318; PFAM:PF01565; SMCOG1138:FAD linked oxidase domain protein; antiSMASH:Cluster_3.2; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_function: GO:0071949 - FAD binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_30469A COG:S; EggNog:ENOG410PKM8; InterPro:IPR012535; PFAM:PF08045; antiSMASH:Cluster_3.2 AKAW2_30470S COG:H; EggNog:ENOG410PG5T; InterPro:IPR033749,IPR008949,IPR000092; PFAM:PF00348; SMCOG1182:Polyprenyl synthetase; antiSMASH:Cluster_3.2; go_process: GO:0008299 - isoprenoid biosynthetic process [Evidence IEA] AKAW2_30471A COG:L; EggNog:ENOG410PN5B; InterPro:IPR036063,IPR002625; PFAM:PF01713; antiSMASH:Cluster_3.2 AKAW2_30472S COG:D,T; EggNog:ENOG410PHS2; InterPro:IPR002975,IPR027417,IPR011025,IPR001019; PFAM:PF00503,PF00025; antiSMASH:Cluster_3.2; go_component: GO:0005834 - heterotrimeric G-protein complex [Evidence IEA]; go_function: GO:0001664 - G protein-coupled receptor binding [Evidence IEA]; go_function: GO:0003924 - GTPase activity [Evidence IEA]; go_function: GO:0005525 - GTP binding [Evidence IEA]; go_function: GO:0019001 - guanyl nucleotide binding [Evidence IEA]; go_function: GO:0031683 - G-protein beta/gamma-subunit complex binding [Evidence IEA]; go_process: GO:0007165 - signal transduction [Evidence IEA]; go_process: GO:0007186 - G protein-coupled receptor signaling pathway [Evidence IEA] AKAW2_30473A COG:S; EggNog:ENOG410PTBQ; InterPro:IPR019150; TransMembrane:1 (i315-338o); antiSMASH:Cluster_3.2 AKAW2_30474A COG:S; EggNog:ENOG410Q2TS; TransMembrane:1 (o15-37i) AKAW2_30475A COG:I; EggNog:ENOG410PI82; InterPro:IPR042099,IPR000873,IPR020845; PFAM:PF00501; TransMembrane:1 (i81-100o) AKAW2_30476A COG:U; EggNog:ENOG410PIUM; InterPro:IPR018864,IPR041634; PFAM:PF10487,PF18378; go_function: GO:0017056 - structural constituent of nuclear pore [Evidence IEA] AKAW2_30477S BUSCO:EOG09261OLD; COG:E; EggNog:ENOG410PGPM; InterPro:IPR011060,IPR013798,IPR013785,IPR006221, IPR029062,IPR017926,IPR016302,IPR001240,IPR001468; MEROPS:MER0045094; PFAM:PF00697,PF00218,PF00117; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0004049 - anthranilate synthase activity [Evidence IEA]; go_function: GO:0004425 - indole-3-glycerol-phosphate synthase activity [Evidence IEA]; go_function: GO:0004640 - phosphoribosylanthranilate isomerase activity [Evidence IEA]; go_process: GO:0006568 - tryptophan metabolic process [Evidence IEA] AKAW2_30478S COG:L; EggNog:ENOG410PTJR; InterPro:IPR036930,IPR036420,IPR008893; PFAM:PF05406 AKAW2_30479A BUSCO:EOG09263LR1; COG:A; EggNog:ENOG410PII8; InterPro:IPR007109; PFAM:PF04427 AKAW2_30480S COG:A; EggNog:ENOG410PHFX; InterPro:IPR041677,IPR018999,IPR027417,IPR041679, IPR014001,IPR040812; PFAM:PF18141,PF13245,PF13087,PF04851,PF13604; go_component: GO:0005737 - cytoplasm [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0004386 - helicase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0000184 - nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [Evidence IEA] AKAW2_30481S COG:K; EggNog:ENOG410PMUS; InterPro:IPR013087,IPR031514 AKAW2_30482S COG:V; EggNog:ENOG410PN3R; InterPro:IPR029021,IPR020422,IPR000340; PFAM:PF00782; go_function: GO:0008138 - protein tyrosine/serine/threonine phosphatase activity [Evidence IEA]; go_process: GO:0006470 - protein dephosphorylation [Evidence IEA]; go_process: GO:0016311 - dephosphorylation [Evidence IEA] AKAW2_30483S COG:S; EggNog:ENOG410PXUI AKAW2_30484S COG:S; EggNog:ENOG410PXUI AKAW2_30485S COG:F; EggNog:ENOG410PKDK; InterPro:IPR006680,IPR011059,IPR032466,IPR011778; MEROPS:MER0015112; PFAM:PF01979; go_component: GO:0005737 - cytoplasm [Evidence IEA]; go_function: GO:0016787 - hydrolase activity [Evidence IEA]; go_function: GO:0016810 - hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [Evidence IEA] AKAW2_30486A InterPro:IPR001810; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_30487S COG:K; EggNog:ENOG410PFNH; InterPro:IPR038718,IPR000330,IPR027417,IPR014001, IPR001650; PFAM:PF00176,PF00271,PF04851; go_function: GO:0005524 - ATP binding [Evidence IEA] AKAW2_30488A COG:Z; EggNog:ENOG410QDVD; InterPro:IPR011992,IPR025604,IPR002048,IPR018247, IPR000261; PFAM:PF00036,PF12763,PF12761; go_function: GO:0005509 - calcium ion binding [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0006897 - endocytosis [Evidence IEA]; go_process: GO:0007015 - actin filament organization [Evidence IEA] AKAW2_30489A BUSCO:EOG092653VU; COG:S; EggNog:ENOG410PM3N; InterPro:IPR018786; PFAM:PF10173 AKAW2_30490S COG:S; EggNog:ENOG410PJ0T; InterPro:IPR037737; TransMembrane:4 (i230-250o262-282i303-322o353-378i) AKAW2_30491A COG:S; EggNog:ENOG410PP4R; InterPro:IPR014500,IPR014710,IPR011051,IPR013096; PFAM:PF07883 AKAW2_30492S COG:D; EggNog:ENOG410PFP9; InterPro:IPR036317,IPR001373,IPR036388,IPR019559, IPR036390,IPR016159,IPR016158; PFAM:PF10557,PF00888; go_function: GO:0031625 - ubiquitin protein ligase binding [Evidence IEA]; go_process: GO:0006511 - ubiquitin-dependent protein catabolic process [Evidence IEA] AKAW2_30493A BUSCO:EOG09262V8E; COG:S; EggNog:ENOG410PGRT; InterPro:IPR037516,IPR018307; PFAM:PF09794 AKAW2_30494A COG:K; EggNog:ENOG410PF8J; InterPro:IPR017441,IPR008352,IPR008271,IPR038783, IPR003527,IPR000719,IPR011009; PFAM:PF07714,PF00069; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0004707 - MAP kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA]; go_process: GO:0051403 - stress-activated MAPK cascade [Evidence IEA] AKAW2_30496S COG:D,T; EggNog:ENOG410PFYM; InterPro:IPR002975,IPR027417,IPR011025,IPR001019; PFAM:PF00503,PF00025; go_component: GO:0005834 - heterotrimeric G-protein complex [Evidence IEA]; go_function: GO:0001664 - G protein-coupled receptor binding [Evidence IEA]; go_function: GO:0003924 - GTPase activity [Evidence IEA]; go_function: GO:0005525 - GTP binding [Evidence IEA]; go_function: GO:0019001 - guanyl nucleotide binding [Evidence IEA]; go_function: GO:0031683 - G-protein beta/gamma-subunit complex binding [Evidence IEA]; go_process: GO:0007165 - signal transduction [Evidence IEA]; go_process: GO:0007186 - G protein-coupled receptor signaling pathway [Evidence IEA] AKAW2_30497S CAZy:GT35; COG:G; EggNog:ENOG410PFTQ; InterPro:IPR011833,IPR000811; PFAM:PF00343; go_function: GO:0004645 - 1,4-alpha-oligoglucan phosphorylase activity [Evidence IEA]; go_function: GO:0008184 - glycogen phosphorylase activity [Evidence IEA]; go_function: GO:0030170 - pyridoxal phosphate binding [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_30498A COG:I; EggNog:ENOG410PI0S; InterPro:IPR027417,IPR003593,IPR011527,IPR003439, IPR036640; PFAM:PF06472,PF00005; TransMembrane:3 (i113-131o151-173i347-367o); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0042626 - ATPase-coupled transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_30499A COG:S; EggNog:ENOG410PFDE; InterPro:IPR032675 AKAW2_30500A BUSCO:EOG0926419M; COG:J; EggNog:ENOG410PH7A; InterPro:IPR005485,IPR025607; PFAM:PF17144,PF14204; go_component: GO:0005840 - ribosome [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_function: GO:0008097 - 5S rRNA binding [Evidence IEA]; go_process: GO:0006412 - translation [Evidence IEA] AKAW2_30501A COG:S; EggNog:ENOG410PG5X; InterPro:IPR036412,IPR023198,IPR023214,IPR006439; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_30502S COG:S; EggNog:ENOG410PRN3; InterPro:IPR025207; PFAM:PF13093; go_component: GO:0031511 - Mis6-Sim4 complex [Evidence IEA] AKAW2_30503S COG:S; EggNog:ENOG410PPY9 AKAW2_30504A COG:S; EggNog:ENOG410PPV8; InterPro:IPR008000,IPR011008; PFAM:PF05336; go_function: GO:0016857 - racemase and epimerase activity, acting on carbohydrates and derivatives [Evidence IEA] AKAW2_30506A COG:P; EggNog:ENOG410PJE9; InterPro:IPR020846,IPR011701,IPR004737,IPR036259; PFAM:PF07690; TransMembrane:12 (i35-53o73-90i102-121o127-147i159-181o201-219i306-329o349- 374i386-405o411-434i441-465o471-493i); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0015112 - nitrate transmembrane transporter activity [Evidence IEA]; go_function: GO:0015113 - nitrite transmembrane transporter activity [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0015706 - nitrate transport [Evidence IEA]; go_process: GO:0015707 - nitrite transport [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_30507A COG:C; EggNog:ENOG410PJ0A; InterPro:IPR036188,IPR005117,IPR017941,IPR041854, IPR006066,IPR006067,IPR012748,IPR036136,IPR036922, IPR023753,IPR007419; PFAM:PF07992,PF01077,PF13806,PF04324,PF00070, PF00355,PF03460; TransMembrane:1 (i45-62o); go_function: GO:0008942 - nitrite reductase [NAD(P)H] activity [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_function: GO:0051536 - iron-sulfur cluster binding [Evidence IEA]; go_function: GO:0051537 - 2 iron, 2 sulfur cluster binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_30508S COG:C; EggNog:ENOG410PGA1; InterPro:IPR001834,IPR017927,IPR008333,IPR008335, IPR039261,IPR036400,IPR014756,IPR012137,IPR036374, IPR001433,IPR017938,IPR022407,IPR018506,IPR000572, IPR001709,IPR005066,IPR001199; PFAM:PF00173,PF00174,PF00175,PF00970,PF03404; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_function: GO:0030151 - molybdenum ion binding [Evidence IEA]; go_function: GO:0043546 - molybdopterin cofactor binding [Evidence IEA]; go_function: GO:0050464 - nitrate reductase (NADPH) activity [Evidence IEA]; go_process: GO:0006809 - nitric oxide biosynthetic process [Evidence IEA]; go_process: GO:0042128 - nitrate assimilation [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_30509S COG:S; EggNog:ENOG410PP1B; InterPro:IPR012423; PFAM:PF07904; go_component: GO:0005634 - nucleus [Evidence IEA]; go_component: GO:0043189 - H4/H2A histone acetyltransferase complex [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_30510A COG:E; EggNog:ENOG410PFWG; InterPro:IPR004434,IPR024084,IPR019818; PFAM:PF00180; go_function: GO:0000287 - magnesium ion binding [Evidence IEA]; go_function: GO:0004449 - isocitrate dehydrogenase (NAD+) activity [Evidence IEA]; go_function: GO:0016616 - oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Evidence IEA]; go_function: GO:0051287 - NAD binding [Evidence IEA]; go_process: GO:0006099 - tricarboxylic acid cycle [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_30511S COG:U; EggNog:ENOG410PI7J; InterPro:IPR039481,IPR029175; PFAM:PF08700,PF15469; go_component: GO:0000145 - exocyst [Evidence IEA]; go_process: GO:0006893 - Golgi to plasma membrane transport [Evidence IEA] AKAW2_30512A COG:S; EggNog:ENOG410PSHM AKAW2_30513S COG:S; EggNog:ENOG410PJWN; InterPro:IPR025261,IPR033473; PFAM:PF13889,PF13915 AKAW2_30514A BUSCO:EOG09262KZ3; COG:T,Z; EggNog:ENOG410PIFG; InterPro:IPR017901,IPR001837,IPR036223,IPR036222, IPR028419,IPR006599,IPR013912,IPR016098,IPR013992, IPR018106; PFAM:PF08603,PF01213; go_function: GO:0003779 - actin binding [Evidence IEA]; go_process: GO:0000902 - cell morphogenesis [Evidence IEA]; go_process: GO:0007010 - cytoskeleton organization [Evidence IEA]; go_process: GO:0007015 - actin filament organization [Evidence IEA] AKAW2_30515S COG:G; EggNog:ENOG410PK8Q; InterPro:IPR029056,IPR011611,IPR034094; PFAM:PF00294 AKAW2_30516A COG:S; EggNog:ENOG410PQUN; TransMembrane:1 (o29-48i) AKAW2_30517S BUSCO:EOG09263CGP; COG:J; EggNog:ENOG410PFDN; InterPro:IPR000999,IPR014720,IPR036389; PFAM:PF00035,PF00636; go_function: GO:0004525 - ribonuclease III activity [Evidence IEA]; go_process: GO:0006396 - RNA processing [Evidence IEA] AKAW2_30518A COG:S; EggNog:ENOG410PXC6; InterPro:IPR007541; PFAM:PF04450 AKAW2_30519S BUSCO:EOG09260XSR; COG:Z; EggNog:ENOG410PJNX; InterPro:IPR016024,IPR011989,IPR021133,IPR034085, IPR024395; PFAM:PF12348 AKAW2_30520S COG:Q; EggNog:ENOG410PJUU; InterPro:IPR017871,IPR027417,IPR003593,IPR039421, IPR011527,IPR003439,IPR036640; PFAM:PF00005,PF00664; TransMembrane:12 (i54-78o110-132i183-202o208-229i289-308o328-355i758- 784o804-829i883-903o909-928i989-1010o1022-1045i); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA]; go_function: GO:0042626 - ATPase-coupled transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_30521S COG:T; EggNog:ENOG410QDMX; InterPro:IPR001781,IPR000198,IPR008936; PFAM:PF00620,PF00412; go_process: GO:0007165 - signal transduction [Evidence IEA] AKAW2_30522A COG:S; EggNog:ENOG410PJ1T; InterPro:IPR013964; PFAM:PF08655; go_component: GO:0042729 - DASH complex [Evidence IEA]; go_component: GO:0072686 - mitotic spindle [Evidence IEA]; go_process: GO:0008608 - attachment of spindle microtubules to kinetochore [Evidence IEA] AKAW2_30523S COG:S; EggNog:ENOG410Q0BM; TransMembrane:1 (o6-24i) AKAW2_30524S COG:I; EggNog:ENOG410PJ8U; InterPro:IPR016039,IPR020613,IPR020617,IPR020616, IPR020615,IPR002155; PFAM:PF00108,PF02803; go_function: GO:0016746 - transferase activity, transferring acyl groups [Evidence IEA]; go_function: GO:0016747 - transferase activity, transferring acyl groups other than amino-acyl groups [Evidence IEA] AKAW2_30525A COG:D; EggNog:ENOG410PG8I; InterPro:IPR029071,IPR013536; MEROPS:MER0215827; PFAM:PF08325 AKAW2_30526A COG:S; EggNog:ENOG410PHG2; InterPro:IPR009644,IPR007074; SECRETED:SignalP(1-21) AKAW2_30527A COG:Q; EggNog:ENOG410PGKJ; InterPro:IPR017871,IPR027417,IPR003593,IPR011527, IPR003439,IPR036640; PFAM:PF00005,PF00664; SMCOG1288:ABC transporter related protein; TransMembrane:11 (i49-73o98-124i174-194o200-223i277-308o341-362i711- 734o754-774i835-857o863-881i933-958o); antiSMASH:Cluster_3.3; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA]; go_function: GO:0042626 - ATPase-coupled transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_30528A COG:S; EggNog:ENOG410PKYW; InterPro:IPR023213,IPR003480; PFAM:PF02458; antiSMASH:Cluster_3.3; go_function: GO:0016747 - transferase activity, transferring acyl groups other than amino-acyl groups [Evidence IEA] AKAW2_30529A COG:I; EggNog:ENOG410PGP1; InterPro:IPR018333,IPR008930,IPR032696,IPR032697; PFAM:PF13249,PF00432; antiSMASH:Cluster_3.3; go_component: GO:0005811 - lipid droplet [Evidence IEA]; go_function: GO:0000250 - lanosterol synthase activity [Evidence IEA]; go_function: GO:0016866 - intramolecular transferase activity [Evidence IEA]; go_function: GO:0042300 - beta-amyrin synthase activity [Evidence IEA]; go_process: GO:0016104 - triterpenoid biosynthetic process [Evidence IEA] AKAW2_30530S COG:Q; EggNog:ENOG410Q240; InterPro:IPR001128,IPR017972,IPR036396; PFAM:PF00067; SMCOG1034:cytochrome P450; TransMembrane:1 (o25-46i); antiSMASH:Cluster_3.3; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_30531A COG:Q; EggNog:ENOG410PV59; InterPro:IPR036291,IPR002347; PFAM:PF00106,PF13561; SMCOG1001:short-chain dehydrogenase/reductase SDR; antiSMASH:Cluster_3.3; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_30532S COG:S; EggNog:ENOG410Q07K; TransMembrane:1 (o403-421i); antiSMASH:Cluster_3.3 AKAW2_30533A BUSCO:EOG092616YZ; COG:O; EggNog:ENOG410PFSD; InterPro:IPR018181,IPR029047,IPR029048,IPR013126, IPR043129; PFAM:PF00012,PF06723; antiSMASH:Cluster_3.3 AKAW2_30534A COG:M; EggNog:ENOG410PJ2V; InterPro:IPR029044,IPR004835; PFAM:PF03142,PF13632,PF13641; TransMembrane:4 (n2-13c17/18o41-63i394-411o417-435i442-465o); antiSMASH:Cluster_3.3; go_function: GO:0004100 - chitin synthase activity [Evidence IEA]; go_function: GO:0016758 - transferase activity, transferring hexosyl groups [Evidence IEA] AKAW2_30535A COG:S; EggNog:ENOG410PT0V AKAW2_30536S COG:A; EggNog:ENOG410QDTN; InterPro:IPR000504,IPR036388,IPR035979,IPR006630, IPR012677,IPR036390,IPR002344; PFAM:PF05383,PF00076; go_component: GO:0005634 - nucleus [Evidence IEA]; go_component: GO:1990904 - ribonucleoprotein complex [Evidence IEA]; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0003723 - RNA binding [Evidence IEA]; go_process: GO:0006396 - RNA processing [Evidence IEA] AKAW2_30537A COG:J; EggNog:ENOG410PJ8I; InterPro:IPR036974,IPR036885,IPR001950,IPR015947, IPR039757,IPR039759,IPR036877; PFAM:PF01253; go_function: GO:0003723 - RNA binding [Evidence IEA]; go_function: GO:0003743 - translation initiation factor activity [Evidence IEA]; go_process: GO:0001731 - formation of translation preinitiation complex [Evidence IEA]; go_process: GO:0006413 - translational initiation [Evidence IEA] AKAW2_30539A CAZy:AA9; COG:G; EggNog:ENOG410PNFI; InterPro:IPR005103; PFAM:PF03443; SECRETED:SignalP(1-25) AKAW2_30540S COG:K; EggNog:ENOG410QDMM; InterPro:IPR014756,IPR002110,IPR036770,IPR013783, IPR020683,IPR002909; PFAM:PF12796,PF00023,PF13637,PF01833,PF13857; TransMembrane:2 (o1015-1033i1362-1383o); go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_30541S BUSCO:EOG09260NHB; COG:K; EggNog:ENOG410PJJT; InterPro:IPR022233; PFAM:PF12584 AKAW2_30542S COG:I; EggNog:ENOG410PGFX; InterPro:IPR005804; PFAM:PF00487; TransMembrane:4 (i92-111o123-144i289-307o313-337i); go_process: GO:0006629 - lipid metabolic process [Evidence IEA] AKAW2_30543A COG:L; EggNog:ENOG410PIMG; InterPro:IPR027417,IPR003593,IPR020588,IPR013632; PFAM:PF13481,PF08423,PF06745; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0008094 - DNA-dependent ATPase activity [Evidence IEA]; go_process: GO:0006281 - DNA repair [Evidence IEA] AKAW2_30544S COG:S; EggNog:ENOG410PKNN; InterPro:IPR038491,IPR021740,IPR037525 AKAW2_30545S COG:A; EggNog:ENOG410PYB5 AKAW2_30546A COG:S; EggNog:ENOG410PKB0; InterPro:IPR007325,IPR037175; PFAM:PF04199; go_function: GO:0004061 - arylformamidase activity [Evidence IEA]; go_process: GO:0019441 - tryptophan catabolic process to kynurenine [Evidence IEA] AKAW2_30547A COG:U; EggNog:ENOG410PR3C; InterPro:IPR025609,IPR010920,IPR025761,IPR025762, IPR019050,IPR025768; PFAM:PF09532,PF12701 AKAW2_30548S COG:S; EggNog:ENOG410PFI0; InterPro:IPR036322,IPR015943,IPR019775,IPR001680, IPR017986; PFAM:PF00400; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_30549S TransMembrane:1 (o24-42i) AKAW2_30550S COG:O; EggNog:ENOG410PK9A; InterPro:IPR004879,IPR036249,IPR008928,IPR024705, IPR012341; PFAM:PF03190; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_30551S COG:S; EggNog:ENOG410PRT6; InterPro:IPR018244,IPR014044,IPR001283,IPR035940; PFAM:PF00188; SECRETED:SignalP(1-17); go_component: GO:0005576 - extracellular region [Evidence IEA] AKAW2_30552S COG:I; EggNog:ENOG410PGGI; InterPro:IPR000542,IPR039551,IPR042231,IPR042232; PFAM:PF00755; go_function: GO:0016746 - transferase activity, transferring acyl groups [Evidence IEA] AKAW2_30553S COG:L; EggNog:ENOG410PGR5; InterPro:IPR034732,IPR003349,IPR001965,IPR003347, IPR013083; PFAM:PF13832,PF02375,PF02373,PF13771 AKAW2_30554S COG:E; EggNog:ENOG410PHFY; InterPro:IPR002293; PFAM:PF00324,PF13520; TransMembrane:12 (i27-51o63-96i116-140o152-172i184-202o222-242i263-285o317- 343i364-384o390-411i432-455o461-482i); go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_30555S COG:S; EggNog:ENOG410PK4J; InterPro:IPR014352,IPR035984,IPR000582; PFAM:PF00887; TransMembrane:1 (o345-367i); antiSMASH:Cluster_3.4; go_function: GO:0000062 - fatty-acyl-CoA binding [Evidence IEA] AKAW2_30556A COG:C; EggNog:ENOG410PNJB; InterPro:IPR010625,IPR016680; PFAM:PF06747; antiSMASH:Cluster_3.4; go_process: GO:0006120 - mitochondrial electron transport, NADH to ubiquinone [Evidence IEA] AKAW2_30557S COG:U,Y; EggNog:ENOG410PI8F; InterPro:IPR024864,IPR025712,IPR025574; PFAM:PF18570,PF13874,PF13634; antiSMASH:Cluster_3.4; go_component: GO:0005643 - nuclear pore [Evidence IEA] AKAW2_30558S BUSCO:EOG0926390Q; COG:K; EggNog:ENOG410PF9A; InterPro:IPR017923,IPR035441; PFAM:PF08711; antiSMASH:Cluster_3.4; go_component: GO:0005634 - nucleus [Evidence IEA] AKAW2_30559S COG:S; EggNog:ENOG410PIQU; InterPro:IPR040153,IPR007667; PFAM:PF04588; TransMembrane:3 (o20-38i117-135o147-168i); antiSMASH:Cluster_3.4 AKAW2_30560S COG:S; EggNog:ENOG410PSJS; InterPro:IPR036322,IPR015943,IPR019775,IPR001680, IPR011659,IPR017986; PFAM:PF00400; SMCOG1173:WD-40 repeat-containing protein; antiSMASH:Cluster_3.4; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_30561S COG:S; EggNog:ENOG410PVPZ; InterPro:IPR011009,IPR002575; PFAM:PF01636; antiSMASH:Cluster_3.4 AKAW2_30562S COG:S; EggNog:ENOG410Q2IR; antiSMASH:Cluster_3.4 AKAW2_30563S COG:S; EggNog:ENOG410PQ74; TransMembrane:7 (o16-38i50-71o97-120i132-154o174-196i208-228o240-267i); antiSMASH:Cluster_3.4 AKAW2_30564S COG:I; EggNog:ENOG410PJ8T; InterPro:IPR000873,IPR009081,IPR006162,IPR036736, IPR036291,IPR013120,IPR042099,IPR020845; PFAM:PF00501,PF16363,PF00550,PF01370,PF07993; SMCOG1002:AMP-dependent synthetase and ligase; antiSMASH:Cluster_3.4 AKAW2_30565S COG:S; EggNog:ENOG410PKVH; antiSMASH:Cluster_3.4 AKAW2_30566A InterPro:IPR013087; TransMembrane:2 (i204-225o231-253i); antiSMASH:Cluster_3.4 AKAW2_30567A COG:S; EggNog:ENOG410PWIN; InterPro:IPR029065,IPR013341,IPR036849,IPR013342, IPR034593,IPR029017; PFAM:PF13378,PF02746; SMCOG1268:mandelate racemase/muconate lactonizing enzyme; antiSMASH:Cluster_3.4 AKAW2_30568S COG:S; EggNog:ENOG410PWEJ; TransMembrane:7 (o14-32i44-67o87-110i122-153o173-191i198-219o239-259i); antiSMASH:Cluster_3.4 AKAW2_30569A COG:M; EggNog:ENOG410Q18J; InterPro:IPR000845,IPR035994,IPR002110,IPR027417, IPR036770,IPR020683; PFAM:PF01048,PF12796,PF00023,PF13857,PF13637, PF13606; antiSMASH:Cluster_3.4; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0009116 - nucleoside metabolic process [Evidence IEA] AKAW2_30570A COG:S; EggNog:ENOG410PWU6; InterPro:IPR010730; PFAM:PF06985; antiSMASH:Cluster_3.4 AKAW2_30571A COG:E; EggNog:ENOG410PW72; InterPro:IPR008794; PFAM:PF05544 AKAW2_30572A COG:S; EggNog:ENOG410PW9B AKAW2_30573S COG:C; EggNog:ENOG410PVNJ; InterPro:IPR036188,IPR003953,IPR027477; PFAM:PF13450,PF07992,PF00890 AKAW2_30574A COG:S; EggNog:ENOG410PSEK; InterPro:IPR022703; PFAM:PF12051; TransMembrane:5 (o177-198i205-225o237-255i262-283o324-341i) AKAW2_30576A COG:S; EggNog:ENOG410PVQ3; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_30577S COG:Q; EggNog:ENOG410PFU6; InterPro:IPR036291,IPR002347; PFAM:PF08659,PF00106,PF13561; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_30578S COG:G; EggNog:ENOG410Q1SR; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690,PF00083; TransMembrane:12 (i102-119o139-160i169-190o196-220i227-249o269-290i373- 394o414-433i445-464o476-495i507-525o531-550i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_30579A COG:H; EggNog:ENOG410PK7M; InterPro:IPR008949,IPR000092; PFAM:PF19086,PF00348; go_process: GO:0008299 - isoprenoid biosynthetic process [Evidence IEA] AKAW2_30580S InterPro:IPR008949; PFAM:PF19086 AKAW2_30581S COG:S; EggNog:ENOG410PT38; InterPro:IPR032710 AKAW2_30582S COG:O; EggNog:ENOG410PI5I; InterPro:IPR023828,IPR000209,IPR030400,IPR015366, IPR036852; MEROPS:MER0078639; PFAM:PF09286,PF00082; SECRETED:SignalP(1-19); go_function: GO:0004252 - serine-type endopeptidase activity [Evidence IEA]; go_function: GO:0008236 - serine-type peptidase activity [Evidence IEA]; go_process: GO:0006508 - proteolysis [Evidence IEA] AKAW2_30583S CAZy:GH131; COG:S; EggNog:ENOG410PFES; InterPro:IPR041524; PFAM:PF18271; SECRETED:SignalP(1-15) AKAW2_30584A COG:S; EggNog:ENOG410Q2YZ; InterPro:IPR002523,IPR002110,IPR020683,IPR036770; PFAM:PF13857,PF12796,PF00023,PF01544,PF13637, PF13606; TransMembrane:2 (i712-730o742-761i); go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_function: GO:0046873 - metal ion transmembrane transporter activity [Evidence IEA]; go_process: GO:0030001 - metal ion transport [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_30585S COG:E; EggNog:ENOG410PFC6; InterPro:IPR000109,IPR018456,IPR036259; PFAM:PF00854; TransMembrane:11 (o135-155i167-187o193-212i252-274o280-301i375-392o422- 439i451-474o494-513i534-553o559-579i); go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0006857 - oligopeptide transport [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_30586S COG:O; EggNog:ENOG410Q1A5; InterPro:IPR006076,IPR036188; PFAM:PF01266; TransMembrane:1 (i7-26o); go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_30587S COG:Q; EggNog:ENOG410PP34; InterPro:IPR002347,IPR036291,IPR020904; PFAM:PF00106,PF13561,PF08659,PF01370; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_30588S COG:Q; EggNog:ENOG410PVFX; InterPro:IPR001128,IPR017972,IPR002401,IPR036396; SECRETED:SignalP(1-21); go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_30589S COG:S; EggNog:ENOG410PIK0; InterPro:IPR010775; PFAM:PF07103; TransMembrane:2 (o461-479i486-505o) AKAW2_30590S COG:S; EggNog:ENOG410PGJC; InterPro:IPR002937,IPR036188; PFAM:PF01593,PF13450; TransMembrane:1 (o452-470i); go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_30591S COG:S; EggNog:ENOG410Q2EC; InterPro:IPR007325,IPR037175; PFAM:PF04199; go_function: GO:0004061 - arylformamidase activity [Evidence IEA]; go_process: GO:0019441 - tryptophan catabolic process to kynurenine [Evidence IEA] AKAW2_30592A COG:U; EggNog:ENOG410PVXW; InterPro:IPR040632,IPR027417; PFAM:PF17784; TransMembrane:1 (i259-281o) AKAW2_30593S COG:S; EggNog:ENOG410QE8M; InterPro:IPR029069; PFAM:PF13279; TransMembrane:1 (o12-30i) AKAW2_30594A InterPro:IPR008427; PFAM:PF05730; SECRETED:SignalP(1-18) AKAW2_30595A COG:Q; EggNog:ENOG410PFN7; InterPro:IPR034001,IPR043926,IPR027417,IPR003593, IPR010929,IPR017871,IPR029481,IPR003439,IPR013525, IPR034003; PFAM:PF01061,PF00005,PF06422,PF14510; TransMembrane:13 (o514-534i546-568o588-612i624-645o651-673i760-777o1181- 1199i1211-1234o1254-1280i1292-1313o1319-1339i1346- 1364o1446-1465i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA]; go_function: GO:0042626 - ATPase-coupled transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_30596A COG:O; EggNog:ENOG410PKA2; InterPro:IPR008758,IPR029058; MEROPS:MER0093133; SECRETED:SignalP(1-22); go_function: GO:0008236 - serine-type peptidase activity [Evidence IEA]; go_process: GO:0006508 - proteolysis [Evidence IEA] AKAW2_30597A BUSCO:EOG092610TN; COG:Q; EggNog:ENOG410PHCS; InterPro:IPR027417,IPR008803,IPR030386; PFAM:PF05879,PF02263; TransMembrane:2 (i743-761o767-785i); go_function: GO:0005525 - GTP binding [Evidence IEA] AKAW2_30599A COG:J; EggNog:ENOG410PFSB; InterPro:IPR041709,IPR005225,IPR027417,IPR000795, IPR031157,IPR004161,IPR004160,IPR009000,IPR004541, IPR009001,IPR033720; PFAM:PF03143,PF00009,PF03144,PF01926; go_function: GO:0003746 - translation elongation factor activity [Evidence IEA]; go_function: GO:0003924 - GTPase activity [Evidence IEA]; go_function: GO:0005525 - GTP binding [Evidence IEA]; go_process: GO:0006414 - translational elongation [Evidence IEA] AKAW2_30600A COG:J; EggNog:ENOG410PSJU; InterPro:IPR036788,IPR001288; go_function: GO:0003743 - translation initiation factor activity [Evidence IEA]; go_process: GO:0006413 - translational initiation [Evidence IEA] AKAW2_30601A COG:S; EggNog:ENOG410PYK7; InterPro:IPR027921; PFAM:PF15370 AKAW2_30602S COG:J; EggNog:ENOG410PKY3; InterPro:IPR001040,IPR023398; PFAM:PF01652; go_function: GO:0003723 - RNA binding [Evidence IEA]; go_function: GO:0003743 - translation initiation factor activity [Evidence IEA]; go_process: GO:0006413 - translational initiation [Evidence IEA] AKAW2_30603A COG:S; EggNog:ENOG410PQGD; PFAM:PF05205 AKAW2_30604S COG:S; EggNog:ENOG410PRIC; TransMembrane:1 (o33-50i) AKAW2_30605A COG:P; EggNog:ENOG410PH00; InterPro:IPR027469,IPR002524; PFAM:PF01545; TransMembrane:6 (i158-175o187-205i226-248o268-291i312-335o341-362i); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0008324 - cation transmembrane transporter activity [Evidence IEA]; go_process: GO:0006812 - cation transport [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_30606A BUSCO:EOG09264SUZ; COG:E; EggNog:ENOG410PQWU; InterPro:IPR017453,IPR033753,IPR002930,IPR000089, IPR003016,IPR011053; PFAM:PF01597; go_component: GO:0005960 - glycine cleavage complex [Evidence IEA]; go_process: GO:0019464 - glycine decarboxylation via glycine cleavage system [Evidence IEA] AKAW2_30607S COG:J; EggNog:ENOG410PRI7; InterPro:IPR035980,IPR014717,IPR000529; PFAM:PF01250; go_component: GO:0005840 - ribosome [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_function: GO:0019843 - rRNA binding [Evidence IEA]; go_process: GO:0006412 - translation [Evidence IEA] AKAW2_30608S COG:S; EggNog:ENOG410PRWZ; InterPro:IPR003703,IPR029069,IPR042171; PFAM:PF13622; go_function: GO:0047617 - acyl-CoA hydrolase activity [Evidence IEA]; go_process: GO:0006637 - acyl-CoA metabolic process [Evidence IEA] AKAW2_30609S COG:S; EggNog:ENOG410PI6G; InterPro:IPR029058 AKAW2_30610A COG:U; EggNog:ENOG410PGXD; InterPro:IPR022057; PFAM:PF12271; TransMembrane:7 (o48-72i84-106o118-139i151-172o184-209i221-239o254-272i) AKAW2_30611A CAZy:GH114; COG:S; EggNog:ENOG410PJDR; InterPro:IPR017853,IPR004352,IPR013785; PFAM:PF03537; SECRETED:SignalP(1-16); go_function: GO:0003824 - catalytic activity [Evidence IEA] AKAW2_30612A TransMembrane:1 (o37-59i) AKAW2_30613A COG:S; EggNog:ENOG410PKTW; InterPro:IPR000182,IPR016181; PFAM:PF13508,PF00583,PF08445; go_function: GO:0008080 - N-acetyltransferase activity [Evidence IEA] AKAW2_30614A COG:S; EggNog:ENOG410PG49; InterPro:IPR014756,IPR011022; PFAM:PF02752 AKAW2_30615A COG:S; EggNog:ENOG410PTE8 AKAW2_30616S COG:A,J; EggNog:ENOG410PIVD; InterPro:IPR000504,IPR003954,IPR029164,IPR035979, IPR012677,IPR034639,IPR034509; PFAM:PF15159,PF13893,PF00076; TransMembrane:2 (i794-822o842-866i); go_function: GO:0003676 - nucleic acid binding [Evidence IEA] AKAW2_30617A COG:M; EggNog:ENOG410QEFG; InterPro:IPR026869,IPR029055,IPR017932; PFAM:PF13522 AKAW2_30618S BUSCO:EOG09260KUC; COG:U; EggNog:ENOG410PFSZ; InterPro:IPR019762,IPR030381,IPR027417,IPR001401, IPR000375,IPR022812,IPR020850; PFAM:PF00350,PF01031,PF01926; TransMembrane:1 (i77-97o); go_function: GO:0003924 - GTPase activity [Evidence IEA]; go_function: GO:0005525 - GTP binding [Evidence IEA] AKAW2_30619A COG:C; EggNog:ENOG410PIYA; InterPro:IPR036188,IPR023753; PFAM:PF07992,PF00070; TransMembrane:1 (i76-97o); go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_30621S COG:S; EggNog:ENOG410PI1F; InterPro:IPR013922,IPR036915; PFAM:PF08613; go_function: GO:0019901 - protein kinase binding [Evidence IEA]; go_process: GO:0000079 - regulation of cyclin-dependent protein serine/threonine kinase activity [Evidence IEA] AKAW2_30622S BUSCO:EOG09264A2D; COG:J; EggNog:ENOG410PJUA; InterPro:IPR005749,IPR036227,IPR021131,IPR030878; PFAM:PF00828; go_component: GO:0015934 - large ribosomal subunit [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_process: GO:0006412 - translation [Evidence IEA] AKAW2_30623A COG:T; EggNog:ENOG410PHX4; InterPro:IPR017441,IPR008271,IPR000719,IPR011009; PFAM:PF07714,PF00069; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_30624A TransMembrane:1 (o75-97i) AKAW2_30625S COG:T; EggNog:ENOG410PHST; InterPro:IPR001452,IPR036028; PFAM:PF00018; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_30626S COG:S; EggNog:ENOG410Q2FB; InterPro:IPR008816; PFAM:PF13488,PF05433; go_component: GO:0019867 - outer membrane [Evidence IEA] AKAW2_30627S COG:S; EggNog:ENOG410PFAU; InterPro:IPR006603; PFAM:PF04193; TransMembrane:7 (o39-59i71-95o101-123i224-241o253-271i292-309o344-365i) AKAW2_30628A BUSCO:EOG09260Z3X; COG:O; EggNog:ENOG410PG3U; InterPro:IPR004839,IPR015424,IPR015421,IPR015422; PFAM:PF00155; TransMembrane:1 (o154-173i); go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0030170 - pyridoxal phosphate binding [Evidence IEA]; go_process: GO:0009058 - biosynthetic process [Evidence IEA] AKAW2_30629S COG:I; EggNog:ENOG410PIHX; InterPro:IPR000873,IPR032387,IPR005914,IPR042099, IPR020845; PFAM:PF00501,PF16177; go_function: GO:0030729 - acetoacetate-CoA ligase activity [Evidence IEA]; go_process: GO:0006629 - lipid metabolic process [Evidence IEA] AKAW2_30630S COG:O; EggNog:ENOG410PH82; InterPro:IPR007863,IPR011249,IPR011765; MEROPS:MER0079232; PFAM:PF00675,PF05193; go_function: GO:0046872 - metal ion binding [Evidence IEA] AKAW2_30631S COG:U; EggNog:ENOG410PRDT; InterPro:IPR005683; PFAM:PF04281; TransMembrane:1 (o96-116i); go_component: GO:0005741 - mitochondrial outer membrane [Evidence IEA]; go_process: GO:0006886 - intracellular protein transport [Evidence IEA] AKAW2_30632A COG:S; EggNog:ENOG410PQ82; InterPro:IPR025451; PFAM:PF13926 AKAW2_30633S COG:S; EggNog:ENOG410PZ6G; TransMembrane:1 (o218-239i) AKAW2_30634S COG:G; EggNog:ENOG410PJET; InterPro:IPR005829,IPR005828,IPR003663,IPR036259, IPR020846; PFAM:PF00083,PF07690; TransMembrane:10 (i16-34o59-78i90-112o118-139i151-171o183-206i308-330o336- 356i368-386o439-459i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_30635A COG:Q; EggNog:ENOG410PJTN; InterPro:IPR036188,IPR023753; PFAM:PF07992,PF13450; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_30636A COG:S; EggNog:ENOG410Q1FQ AKAW2_30637A COG:K; EggNog:ENOG410PNS8; InterPro:IPR011598,IPR036638; PFAM:PF00010; go_function: GO:0046983 - protein dimerization activity [Evidence IEA] AKAW2_30638A COG:F; EggNog:ENOG410PKRZ; InterPro:IPR023186,IPR036452,IPR001910; PFAM:PF01156 AKAW2_30639S COG:S; EggNog:ENOG410PR78; SECRETED:SignalP(1-19) AKAW2_30640S COG:U; EggNog:ENOG410PHWF; InterPro:IPR002995; PFAM:PF02077; TransMembrane:8 (i60-78o98-118i125-144o150-169i189-207o213-233i240- 259o271-291i); go_component: GO:0016021 - integral component of membrane [Evidence IEA] AKAW2_30641A COG:S; EggNog:ENOG410PJG9 AKAW2_30642A COG:A; EggNog:ENOG410PR0R; InterPro:IPR034103,IPR010920,IPR001163; PFAM:PF01423; go_component: GO:0005688 - U6 snRNP [Evidence IEA]; go_component: GO:0046540 - U4/U6 x U5 tri-snRNP complex [Evidence IEA]; go_process: GO:0000398 - mRNA splicing, via spliceosome [Evidence IEA] AKAW2_30643A COG:S; EggNog:ENOG410PQTF; InterPro:IPR003124; PFAM:PF02205; go_function: GO:0003779 - actin binding [Evidence IEA] AKAW2_30644S COG:S; EggNog:ENOG410PJM2; TransMembrane:2 (i296-317o329-352i) AKAW2_30645A BUSCO:EOG09264LBC; COG:J; EggNog:ENOG410PGQQ; InterPro:IPR002143,IPR028364,IPR023674,IPR016095, IPR023673; PFAM:PF00687; go_component: GO:0015934 - large ribosomal subunit [Evidence IEA]; go_function: GO:0003723 - RNA binding [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_process: GO:0006412 - translation [Evidence IEA] AKAW2_30646A COG:Q; EggNog:ENOG410PJH7; InterPro:IPR036188; PFAM:PF07992,PF13738 AKAW2_30647S COG:S; EggNog:ENOG410PPE3; InterPro:IPR036423,IPR024134,IPR001424; PFAM:PF00080; go_function: GO:0046872 - metal ion binding [Evidence IEA]; go_process: GO:0006801 - superoxide metabolic process [Evidence IEA] AKAW2_30648A COG:E; EggNog:ENOG410PKBA; InterPro:IPR001381,IPR006151,IPR027417,IPR036291, IPR013708,IPR041121,IPR013785,IPR031322; PFAM:PF01202,PF08501,PF01487,PF18317; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0003855 - 3-dehydroquinate dehydratase activity [Evidence IEA]; go_function: GO:0004764 - shikimate 3-dehydrogenase (NADP+) activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_30649S COG:K; EggNog:ENOG410PMP2; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_30650A COG:E; EggNog:ENOG410PNZV; InterPro:IPR036441,IPR018509,IPR001874; PFAM:PF01220; go_function: GO:0003855 - 3-dehydroquinate dehydratase activity [Evidence IEA] AKAW2_30651S COG:G; EggNog:ENOG410PVSJ; InterPro:IPR005829,IPR005828,IPR003663,IPR036259, IPR020846; PFAM:PF00083,PF07690; TransMembrane:12 (i21-48o68-88i100-117o123-148i160-181o193-214i282-304o324- 346i353-373o385-405i426-444o456-477i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_30652S COG:E; EggNog:ENOG410PI98; InterPro:IPR013022,IPR036237; PFAM:PF01261 AKAW2_30653A InterPro:IPR037401,IPR032710; PFAM:PF13577 AKAW2_30654S COG:S; EggNog:ENOG410PSYS; InterPro:IPR037401,IPR032710; PFAM:PF13577 AKAW2_30655S COG:S; EggNog:ENOG410PFE4; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF04082; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_30656A COG:S; EggNog:ENOG410PI27; InterPro:IPR021822; PFAM:PF11885; TransMembrane:1 (i92-113o) AKAW2_30657S COG:S; EggNog:ENOG410PMGX; InterPro:IPR040841; PFAM:PF17648; TransMembrane:1 (o16-33i) AKAW2_30658A COG:U; EggNog:ENOG410PGWR; InterPro:IPR005225,IPR027417,IPR006689; PFAM:PF04670,PF00025,PF08477,PF00071,PF01926, PF09439; go_function: GO:0005525 - GTP binding [Evidence IEA] AKAW2_30659A COG:S; EggNog:ENOG410PIJY; TransMembrane:2 (i493-513o533-554i) AKAW2_30660A COG:I; EggNog:ENOG410PGII; InterPro:IPR011009; PFAM:PF01633,PF01636 AKAW2_30661A COG:S; EggNog:ENOG410PING; InterPro:IPR008978,IPR007052,IPR007051; PFAM:PF04968,PF04969 AKAW2_30662S COG:O; EggNog:ENOG410PSUP; InterPro:IPR036249,IPR008554; PFAM:PF05768 AKAW2_30663A COG:K; EggNog:ENOG410PVBH; InterPro:IPR007219; PFAM:PF04082; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA] AKAW2_30664A COG:S; EggNog:ENOG410Q1K9 AKAW2_30665S COG:G; EggNog:ENOG410QE2U; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:14 (i48-75o87-107i114-134o140-165i172-191o203-223i243- 264o276-296i316-338o350-372i379-396o408-428i440-464o517- 536i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_30666A COG:S; EggNog:ENOG410Q1YG; SECRETED:SignalP(1-30) AKAW2_30667A COG:S; EggNog:ENOG410PN1T; InterPro:IPR023410,IPR000308,IPR036815; TransMembrane:1 (o45-65i) AKAW2_30668A BUSCO:EOG09262645; COG:I; EggNog:ENOG410QE5S AKAW2_30669S COG:S; EggNog:ENOG410PRQ7; InterPro:IPR019350; PFAM:PF11578 AKAW2_30670A BUSCO:EOG09264FOM; COG:U; EggNog:ENOG410PHTG; InterPro:IPR015720,IPR009038,IPR036598; PFAM:PF01105; SECRETED:SignalP(1-21); TransMembrane:1 (n5-16c21/22o173-193i) AKAW2_30671S CAZy:GH17; COG:G; EggNog:ENOG410PK2A; InterPro:IPR017853,IPR000490; PFAM:PF00332; SECRETED:SignalP(1-20); go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_30672S COG:S; EggNog:ENOG410PGN2 AKAW2_30673A InterPro:IPR001810,IPR036047; PFAM:PF00646; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_30674A COG:A; EggNog:ENOG410PJEK; InterPro:IPR038506,IPR012476; PFAM:PF07817; go_component: GO:0005643 - nuclear pore [Evidence IEA]; go_process: GO:0016973 - poly(A)+ mRNA export from nucleus [Evidence IEA] AKAW2_30675S COG:J; EggNog:ENOG410PFBN; InterPro:IPR001900,IPR033771,IPR041093,IPR041505, IPR012340; PFAM:PF17877,PF00773,PF17849; go_function: GO:0003723 - RNA binding [Evidence IEA]; go_function: GO:0004540 - ribonuclease activity [Evidence IEA] AKAW2_30676A COG:O; EggNog:ENOG410PNRI; InterPro:IPR016135,IPR023313,IPR000608; PFAM:PF00179 AKAW2_30677A SECRETED:SignalP(1-21) AKAW2_30678A COG:S; EggNog:ENOG410PSJG; InterPro:IPR018937; PFAM:PF10270; SECRETED:SignalP(1-19); TransMembrane:1 (n7-17c22/23o46-67i) AKAW2_30679A BUSCO:EOG092644ZU; COG:K; EggNog:ENOG410PFG8; InterPro:IPR036219,IPR018940,IPR014038,IPR036282, IPR001326,IPR014717; PFAM:PF00736,PF10587; go_component: GO:0005853 - eukaryotic translation elongation factor 1 complex [Evidence IEA]; go_function: GO:0003746 - translation elongation factor activity [Evidence IEA]; go_process: GO:0006414 - translational elongation [Evidence IEA] AKAW2_30680S COG:O; EggNog:ENOG410PH92; InterPro:IPR028299,IPR003959,IPR041546,IPR027417, IPR003593,IPR019489,IPR018368,IPR001270; PFAM:PF10431,PF00004,PF17871,PF07724,PF00158, PF07728; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA] AKAW2_30681S COG:L; EggNog:ENOG410PF9J; InterPro:IPR036187,IPR027417,IPR011184,IPR000432, IPR007696; PFAM:PF05192,PF00488; TransMembrane:1 (i393-412o); go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0030983 - mismatched DNA binding [Evidence IEA]; go_process: GO:0006298 - mismatch repair [Evidence IEA] AKAW2_30682A BUSCO:EOG09264BOA; COG:B; EggNog:ENOG410PG6U; InterPro:IPR007146,IPR018972; PFAM:PF04000,PF09368 AKAW2_30683S COG:Q; EggNog:ENOG410PIJ0; InterPro:IPR036291,IPR002347; PFAM:PF08659,PF00106,PF13561; TransMembrane:2 (o12-31i193-211o); go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_30684S COG:I; EggNog:ENOG410PFWJ; InterPro:IPR006694; PFAM:PF04116; TransMembrane:3 (n4-15c20/21o55-79i100-119o139-158i); go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0008610 - lipid biosynthetic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_30685A COG:J; EggNog:ENOG410PJFV; InterPro:IPR008991,IPR041997,IPR014722,IPR000915; PFAM:PF01159; go_component: GO:0005840 - ribosome [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_process: GO:0006412 - translation [Evidence IEA] AKAW2_30686S COG:O; EggNog:ENOG410PKMZ; InterPro:IPR032368,IPR038108,IPR038633,IPR006773; PFAM:PF04683,PF16550; go_component: GO:0005634 - nucleus [Evidence IEA]; go_component: GO:0005737 - cytoplasm [Evidence IEA] AKAW2_30687S BUSCO:EOG092600XJ; COG:P; EggNog:ENOG410PFKW; InterPro:IPR002077,IPR027359,IPR011992,IPR005821, IPR002048; PFAM:PF00520; TransMembrane:24 (i343-361o381-403i490-509o515-534i546-569o684-714i756- 774o786-804i816-834o840-860i872-893o951-974i1180- 1205o1225-1244i1256-1273o1279-1296i1308-1332o1429- 1450i1509-1529o1541-1559i1571-1590o1596-1614i1626- 1650o1726-1745i); go_component: GO:0005891 - voltage-gated calcium channel complex [Evidence IEA]; go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0005216 - ion channel activity [Evidence IEA]; go_function: GO:0005245 - voltage-gated calcium channel activity [Evidence IEA]; go_function: GO:0005509 - calcium ion binding [Evidence IEA]; go_process: GO:0006811 - ion transport [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA]; go_process: GO:0070588 - calcium ion transmembrane transport [Evidence IEA] AKAW2_30688S COG:S; EggNog:ENOG410PYQH AKAW2_30689A COG:B; EggNog:ENOG410PNTW; InterPro:IPR007728,IPR001214,IPR003616; PFAM:PF00856,PF05033; go_component: GO:0005634 - nucleus [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_function: GO:0018024 - histone-lysine N-methyltransferase activity [Evidence IEA]; go_process: GO:0034968 - histone lysine methylation [Evidence IEA] AKAW2_30690A COG:T; EggNog:ENOG410PFZJ; InterPro:IPR017441,IPR008271,IPR001772,IPR028375, IPR000719,IPR011009; PFAM:PF07714,PF02149,PF00069; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_30691S COG:A; EggNog:ENOG410PHY6; InterPro:IPR011666,IPR000467,IPR035960; PFAM:PF07713,PF01585; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_process: GO:0006397 - mRNA processing [Evidence IEA] AKAW2_30692S COG:O; EggNog:ENOG410PNST; InterPro:IPR038169,IPR032752,IPR029071,IPR039869; PFAM:PF16455 AKAW2_30693A COG:Q; EggNog:ENOG410Q181; InterPro:IPR034001,IPR017871,IPR027417,IPR003593, IPR010929,IPR029481,IPR003439,IPR013525,IPR034003; PFAM:PF01061,PF00005,PF06422,PF14510; TransMembrane:13 (o520-537i549-570o599-619i626-648o654-676i765-782o1183- 1203i1215-1234o1254-1285i1297-1321o1327-1345i1357- 1378o1451-1470i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA]; go_function: GO:0042626 - ATPase-coupled transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_30694S BUSCO:EOG092646C6; COG:A; EggNog:ENOG410PH7N; InterPro:IPR010301; PFAM:PF05997; go_component: GO:0030688 - preribosome, small subunit precursor [Evidence IEA]; go_process: GO:0006364 - rRNA processing [Evidence IEA] AKAW2_30695A COG:I,T; EggNog:ENOG410PI8C; InterPro:IPR017438,IPR001206,IPR016064; PFAM:PF00781; go_function: GO:0003951 - NAD+ kinase activity [Evidence IEA]; go_function: GO:0016301 - kinase activity [Evidence IEA] AKAW2_30696A BUSCO:EOG09260GKG; COG:U; EggNog:ENOG410PHGH; InterPro:IPR016024,IPR011989,IPR016460,IPR011710, IPR002553,IPR029446; PFAM:PF01602,PF07718,PF12717,PF14806; go_component: GO:0005737 - cytoplasm [Evidence IEA]; go_component: GO:0030117 - membrane coat [Evidence IEA]; go_component: GO:0030126 - COPI vesicle coat [Evidence IEA]; go_function: GO:0005198 - structural molecule activity [Evidence IEA]; go_process: GO:0006886 - intracellular protein transport [Evidence IEA]; go_process: GO:0016192 - vesicle-mediated transport [Evidence IEA] AKAW2_30697S COG:A; EggNog:ENOG410PID9; InterPro:IPR004023,IPR036605; PFAM:PF02792; go_component: GO:0005634 - nucleus [Evidence IEA]; go_component: GO:0035145 - exon-exon junction complex [Evidence IEA]; go_process: GO:0008380 - RNA splicing [Evidence IEA] AKAW2_30698S BUSCO:EOG092648U2; COG:U; EggNog:ENOG410PHR1; InterPro:IPR018618; PFAM:PF09783 AKAW2_30699A BUSCO:EOG092605FC; COG:T; EggNog:ENOG410PF9Z; InterPro:IPR017441,IPR008271,IPR017240,IPR000719, IPR011009; PFAM:PF07714,PF00069; go_component: GO:0005737 - cytoplasm [Evidence IEA]; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0004709 - MAP kinase kinase kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA]; go_process: GO:0051403 - stress-activated MAPK cascade [Evidence IEA] AKAW2_30700S COG:P; EggNog:ENOG410PFGK; InterPro:IPR001905,IPR018047,IPR002229,IPR029020, IPR024041; PFAM:PF00909; TransMembrane:11 (o33-54i66-84o123-144i151-175o187-206i226-243o255-275i287- 304o310-327i339-361o395-413i); go_component: GO:0005887 - integral component of plasma membrane [Evidence IEA]; go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0008519 - ammonium transmembrane transporter activity [Evidence IEA]; go_process: GO:0015696 - ammonium transport [Evidence IEA]; go_process: GO:0072488 - ammonium transmembrane transport [Evidence IEA] AKAW2_30701A COG:Z; EggNog:ENOG410PIDE; InterPro:IPR013838,IPR000217,IPR023123,IPR008280, IPR036525,IPR037103,IPR002453,IPR018316,IPR003008, IPR017975; PFAM:PF03953,PF00091; go_component: GO:0005874 - microtubule [Evidence IEA]; go_function: GO:0003924 - GTPase activity [Evidence IEA]; go_function: GO:0005200 - structural constituent of cytoskeleton [Evidence IEA]; go_function: GO:0005525 - GTP binding [Evidence IEA]; go_process: GO:0007017 - microtubule-based process [Evidence IEA] AKAW2_30702A COG:A; EggNog:ENOG410PJNH; InterPro:IPR000504,IPR035979,IPR034393,IPR034392, IPR012677; PFAM:PF00076; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_process: GO:0000398 - mRNA splicing, via spliceosome [Evidence IEA] AKAW2_30703A COG:S; EggNog:ENOG410PGIZ; TransMembrane:1 (o27-46i) AKAW2_30705A COG:P; EggNog:ENOG410Q1CW; InterPro:IPR038271,IPR026030,IPR001248; PFAM:PF02133; TransMembrane:11 (o74-97i104-123o143-163i175-197o209-227i248-266o286- 309i376-393o399-419i440-462o482-501i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_30706S COG:S; EggNog:ENOG410PU2Q; InterPro:IPR000719,IPR011009,IPR008266; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_30707S COG:P; EggNog:ENOG410PGJZ; InterPro:IPR006068,IPR018303,IPR023298,IPR023299, IPR001757,IPR006408,IPR004014,IPR036412,IPR008250, IPR023214; PFAM:PF00689,PF13246,PF00122,PF00690,PF00702; TransMembrane:9 (i314-333o345-365i516-536o556-583i1005-1026o1038- 1056i1153-1173o1185-1207i1323-1344o); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0000166 - nucleotide binding [Evidence IEA]; go_function: GO:0005388 - calcium transmembrane transporter activity, phosphorylative mechanism [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0070588 - calcium ion transmembrane transport [Evidence IEA] AKAW2_30708S BUSCO:EOG09263J6Z; COG:E; EggNog:ENOG410PFBY; InterPro:IPR006222,IPR027266,IPR029043,IPR013977, IPR028896,IPR006223; PFAM:PF08669,PF01571; go_function: GO:0004047 - aminomethyltransferase activity [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0006546 - glycine catabolic process [Evidence IEA] AKAW2_30709A CAZy:GH92; COG:G; EggNog:ENOG410PM7C; InterPro:IPR041371,IPR014718,IPR012939,IPR008928, IPR005887; PFAM:PF17678,PF07971; SECRETED:SignalP(1-22); go_function: GO:0030246 - carbohydrate binding [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_30710S COG:S; EggNog:ENOG410PMV5; InterPro:IPR029069,IPR006683; PFAM:PF03061; TransMembrane:1 (o73-90i) AKAW2_30711S COG:S; EggNog:ENOG410PIZP; InterPro:IPR036866,IPR001279; PFAM:PF13483,PF12706 AKAW2_30712S COG:S; EggNog:ENOG410Q1QK AKAW2_30713S BUSCO:EOG092631MU; COG:C; EggNog:ENOG410PGJJ; InterPro:IPR004907,IPR036132; PFAM:PF03223; go_component: GO:0033180 - proton-transporting V-type ATPase, V1 domain [Evidence IEA]; go_function: GO:0015078 - proton transmembrane transporter activity [Evidence IEA]; go_process: GO:1902600 - proton transmembrane transport [Evidence IEA] AKAW2_30714A COG:P; EggNog:ENOG410PG9D; InterPro:IPR027417,IPR002891; PFAM:PF01583; go_function: GO:0004020 - adenylylsulfate kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0000103 - sulfate assimilation [Evidence IEA] AKAW2_30715A COG:C; EggNog:ENOG410PK3B; InterPro:IPR016102,IPR017866,IPR005811,IPR036291, IPR003781; PFAM:PF02629,PF00549,PF13607; go_function: GO:0003824 - catalytic activity [Evidence IEA] AKAW2_30716S COG:S; EggNog:ENOG410PSUY AKAW2_30717A COG:O; EggNog:ENOG410PQVP; InterPro:IPR029071,IPR022617,IPR000626; PFAM:PF00240,PF11976; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_30718S COG:U,Y; EggNog:ENOG410PM2X; InterPro:IPR007252; PFAM:PF04121; go_component: GO:0005643 - nuclear pore [Evidence IEA]; go_function: GO:0017056 - structural constituent of nuclear pore [Evidence IEA] AKAW2_30719A COG:Q; EggNog:ENOG410PUDN; InterPro:IPR001128,IPR002403,IPR017972,IPR036396; PFAM:PF00067; TransMembrane:1 (o18-37i); go_function: GO:0004497 - monooxygenase activity [Evidence IEA]; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_30720S COG:S; EggNog:ENOG410Q27X; InterPro:IPR036864,IPR021858,IPR001138; PFAM:PF00172; TransMembrane:1 (i170-187o); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_30721A COG:E; EggNog:ENOG410PHGP; InterPro:IPR013057,IPR002229; PFAM:PF01490; TransMembrane:11 (i72-91o97-122i143-162o174-195i207-228o260-279i291- 314o334-353i374-395o407-426i446-464o); go_component: GO:0005887 - integral component of plasma membrane [Evidence IEA] AKAW2_30722A BUSCO:EOG092612XD; COG:J,K; EggNog:ENOG410PFAJ; InterPro:IPR016024,IPR005612,IPR040155; PFAM:PF03914; TransMembrane:2 (o564-580i729-748o) AKAW2_30723S COG:J; EggNog:ENOG410PHV2 AKAW2_30724S COG:J; EggNog:ENOG410PHV2; InterPro:IPR036621,IPR044140,IPR004154; PFAM:PF03129 AKAW2_30725S COG:L; EggNog:ENOG410PR0Z; InterPro:IPR015797,IPR000086; PFAM:PF00293; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_30727S COG:O; EggNog:ENOG410PR1N; InterPro:IPR004127,IPR011599,IPR009053; PFAM:PF02996; go_component: GO:0016272 - prefoldin complex [Evidence IEA]; go_function: GO:0051082 - unfolded protein binding [Evidence IEA]; go_process: GO:0006457 - protein folding [Evidence IEA] AKAW2_30728A COG:S; EggNog:ENOG410PQZW AKAW2_30729S COG:L; EggNog:ENOG410PHW5; InterPro:IPR003959,IPR001025,IPR027417,IPR003593, IPR041083,IPR043151,IPR020793; PFAM:PF13401,PF00004,PF13191; go_function: GO:0003682 - chromatin binding [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA] AKAW2_30730A BUSCO:EOG09262KUJ; COG:A; EggNog:ENOG410PG61; InterPro:IPR036322,IPR015943,IPR001680,IPR019775, IPR020472,IPR017986; PFAM:PF00400; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_30731S COG:O; EggNog:ENOG410PKPV; InterPro:IPR002110,IPR020683,IPR036770; PFAM:PF13857,PF12796,PF00023,PF13637,PF13606; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_30732A COG:K; EggNog:ENOG410PI1U; InterPro:IPR022092,IPR022091; PFAM:PF12329,PF12325 AKAW2_30733S BUSCO:EOG09263E9V; COG:C; EggNog:ENOG410PKVG; InterPro:IPR016024,IPR011989,IPR004908,IPR011987, IPR038497; PFAM:PF03224,PF11698; go_component: GO:0000221 - vacuolar proton-transporting V-type ATPase, V1 domain [Evidence IEA]; go_function: GO:0046961 - proton-transporting ATPase activity, rotational mechanism [Evidence IEA]; go_process: GO:1902600 - proton transmembrane transport [Evidence IEA] AKAW2_30734S COG:S; EggNog:ENOG410PWY9; InterPro:IPR036864,IPR021858,IPR001138; PFAM:PF00172,PF11951; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_30735S COG:S; EggNog:ENOG410PI5V AKAW2_30736S COG:S; EggNog:ENOG410Q0RQ; InterPro:IPR024316; PFAM:PF12716; TransMembrane:2 (o71-88i95-119o) AKAW2_30737A COG:K; EggNog:ENOG410PHIC; InterPro:IPR004130,IPR027417,IPR030228; PFAM:PF03029 AKAW2_30738S BUSCO:EOG09262QJW; COG:H; EggNog:ENOG410PJ51; InterPro:IPR022631,IPR022630,IPR022636,IPR022628, IPR022629,IPR002133; PFAM:PF00438,PF02772,PF02773; go_function: GO:0004478 - methionine adenosyltransferase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006556 - S-adenosylmethionine biosynthetic process [Evidence IEA] AKAW2_30739S COG:S; EggNog:ENOG410PMC1; InterPro:IPR013948,IPR042511; PFAM:PF08639; go_process: GO:0006270 - DNA replication initiation [Evidence IEA] AKAW2_30740A COG:S; EggNog:ENOG410Q22E AKAW2_30741S COG:S; EggNog:ENOG410PJAD; InterPro:IPR013933; PFAM:PF08624 AKAW2_30742A COG:G; EggNog:ENOG410PJ8M; InterPro:IPR013078,IPR029033; PFAM:PF00300; SECRETED:SignalP(1-19) AKAW2_30743A COG:K; EggNog:ENOG410PTTM; InterPro:IPR017970,IPR001356,IPR009057; PFAM:PF05920,PF00046; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_30744A COG:S; EggNog:ENOG410PK94; InterPro:IPR041492,IPR006439,IPR023198,IPR036412, IPR023214; PFAM:PF13419; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_30745S COG:S; EggNog:ENOG410PFGR; InterPro:IPR030378,IPR027417,IPR006073,IPR014813, IPR023179; PFAM:PF01926,PF08701,PF03193; go_function: GO:0005525 - GTP binding [Evidence IEA] AKAW2_30746S COG:K; EggNog:ENOG410PR88; InterPro:IPR009072,IPR003958; PFAM:PF00808; go_function: GO:0046982 - protein heterodimerization activity [Evidence IEA] AKAW2_30747A COG:B,K; EggNog:ENOG410PHQG; InterPro:IPR029035,IPR003000,IPR026590,IPR026591; PFAM:PF02146; go_function: GO:0070403 - NAD+ binding [Evidence IEA] AKAW2_30748S COG:K; EggNog:ENOG410PM24; InterPro:IPR021665; PFAM:PF11635; TransMembrane:1 (o695-713i); go_component: GO:0016592 - mediator complex [Evidence IEA] AKAW2_30749A BUSCO:EOG09265FTY; COG:J; EggNog:ENOG410PNQF; InterPro:IPR001854,IPR036049; PFAM:PF00831; go_component: GO:0005840 - ribosome [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_process: GO:0006412 - translation [Evidence IEA] AKAW2_30750S BUSCO:EOG09265AL8; COG:U; EggNog:ENOG410PM03; InterPro:IPR023601; PFAM:PF12352; TransMembrane:1 (i209-226o); go_component: GO:0000139 - Golgi membrane [Evidence IEA]; go_component: GO:0005801 - cis-Golgi network [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_process: GO:0006888 - endoplasmic reticulum to Golgi vesicle-mediated transport [Evidence IEA] AKAW2_30751A BUSCO:EOG09263UN3; COG:O; EggNog:ENOG410PK0S; InterPro:IPR007849; PFAM:PF05176 AKAW2_30752S COG:L; EggNog:ENOG410PJ61; InterPro:IPR018944,IPR022312,IPR036420,IPR001357, IPR010996,IPR027421,IPR043519,IPR019843,IPR002008, IPR029398,IPR028207,IPR037160,IPR002054; PFAM:PF10391,PF14716,PF14791,PF14792; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0003887 - DNA-directed DNA polymerase activity [Evidence IEA]; go_function: GO:0016779 - nucleotidyltransferase activity [Evidence IEA]; go_function: GO:0034061 - DNA polymerase activity [Evidence IEA]; go_process: GO:0006281 - DNA repair [Evidence IEA] AKAW2_30753S COG:S; EggNog:ENOG410PJ8W; InterPro:IPR001138; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_30754A SECRETED:SignalP(1-22) AKAW2_30755A COG:S; EggNog:ENOG410Q1Z2 AKAW2_30756A COG:S; EggNog:ENOG410PPSD AKAW2_30757A COG:J; EggNog:ENOG410PGYR; InterPro:IPR001313,IPR016024,IPR040059,IPR012959, IPR033133; PFAM:PF08144; go_function: GO:0003723 - RNA binding [Evidence IEA] AKAW2_30758A COG:S; EggNog:ENOG410PR2Q AKAW2_30760S COG:S; EggNog:ENOG410PS0W; TransMembrane:1 (o13-34i) AKAW2_30761S COG:L; EggNog:ENOG410PFFB; InterPro:IPR016467,IPR027417,IPR003593,IPR011941, IPR010995,IPR033925,IPR020588,IPR020587,IPR013632; PFAM:PF13481,PF08423,PF14520,PF00154; antiSMASH:Cluster_3.5; go_function: GO:0000150 - recombinase activity [Evidence IEA]; go_function: GO:0000166 - nucleotide binding [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0003690 - double-stranded DNA binding [Evidence IEA]; go_function: GO:0003697 - single-stranded DNA binding [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0008094 - DNA-dependent ATPase activity [Evidence IEA]; go_process: GO:0000724 - double-strand break repair via homologous recombination [Evidence IEA]; go_process: GO:0006259 - DNA metabolic process [Evidence IEA]; go_process: GO:0006281 - DNA repair [Evidence IEA]; go_process: GO:1990426 - mitotic recombination-dependent replication fork processing [Evidence IEA] AKAW2_30762S COG:U,Y; EggNog:ENOG410PICI; InterPro:IPR011047,IPR021717; PFAM:PF11715; antiSMASH:Cluster_3.5 AKAW2_30763A COG:Q; EggNog:ENOG410PKKR; InterPro:IPR017871,IPR027417,IPR003593,IPR011527, IPR003439,IPR036640; PFAM:PF00005,PF00664; SMCOG1288:ABC transporter related protein; TransMembrane:17 (o34-56i68-89o101-120i132-151o157-179i270-292o312-333i408- 434o454-471i492-517o537-557i912-938o958-984i1030- 1051o1057-1077i1141-1164o1170-1191i); antiSMASH:Cluster_3.5; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA]; go_function: GO:0042626 - ATPase-coupled transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_30764S InterPro:IPR000873,IPR020845,IPR009081,IPR006162, IPR036736,IPR020806,IPR010071,IPR042099,IPR023213, IPR001242; PFAM:PF00501,PF00668,PF00550; SMCOG1002:AMP-dependent synthetase and ligase; TransMembrane:2 (o3987-4006i4692-4710o); antiSMASH:Cluster_3.5; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0031177 - phosphopantetheine binding [Evidence IEA] AKAW2_30765A COG:U; EggNog:ENOG410Q185; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; SMCOG1106:major facilitator transporter; TransMembrane:12 (i107-124o144-163i175-193o199-222i234-255o267-284i332- 354o374-397i418-437o443-467i479-499o511-533i); antiSMASH:Cluster_3.5; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_30766A COG:S; EggNog:ENOG410QE90; InterPro:IPR019412; PFAM:PF10300; TransMembrane:2 (o252-276i297-317o); antiSMASH:Cluster_3.5 AKAW2_30767S COG:O; EggNog:ENOG410PS8W; InterPro:IPR007834; PFAM:PF05160; antiSMASH:Cluster_3.5; go_component: GO:0008541 - proteasome regulatory particle, lid subcomplex [Evidence IEA]; go_process: GO:0006406 - mRNA export from nucleus [Evidence IEA]; go_process: GO:0043248 - proteasome assembly [Evidence IEA] AKAW2_30768A BUSCO:EOG09262F22; COG:G; EggNog:ENOG410PGBU; InterPro:IPR001576,IPR036043,IPR015824,IPR015911; PFAM:PF00162; antiSMASH:Cluster_3.5; go_function: GO:0004618 - phosphoglycerate kinase activity [Evidence IEA]; go_process: GO:0006096 - glycolytic process [Evidence IEA] AKAW2_30769A COG:S; EggNog:ENOG410PJFR; InterPro:IPR007248; PFAM:PF04117; TransMembrane:6 (i21-41o53-74i128-150o170-190i202-221o227-247i); antiSMASH:Cluster_3.5; go_component: GO:0016021 - integral component of membrane [Evidence IEA] AKAW2_30770A COG:S; EggNog:ENOG410PH9J; InterPro:IPR024662; PFAM:PF12735; antiSMASH:Cluster_3.5; go_component: GO:1990071 - TRAPPII protein complex [Evidence IEA]; go_process: GO:0006891 - intra-Golgi vesicle-mediated transport [Evidence IEA] AKAW2_30771S BUSCO:EOG09261K9J; COG:A; EggNog:ENOG410PGSH; InterPro:IPR036020,IPR039726,IPR036517,IPR002713, IPR001202; PFAM:PF00397,PF01846; antiSMASH:Cluster_3.5; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0045292 - mRNA cis splicing, via spliceosome [Evidence IEA] AKAW2_30772A BUSCO:EOG09261127; COG:J; EggNog:ENOG410PHY8; InterPro:IPR034348,IPR017896,IPR017871,IPR007209, IPR027417,IPR003593,IPR003439,IPR013283; PFAM:PF00037,PF00005,PF04068; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA] AKAW2_30773S BUSCO:EOG092607ZS; COG:K; EggNog:ENOG410Q4IZ; InterPro:IPR027417,IPR000953,IPR000330,IPR038718, IPR023780,IPR001650,IPR014001,IPR023779,IPR025260, IPR016197; PFAM:PF00176,PF00385,PF13907,PF00271; go_function: GO:0005524 - ATP binding [Evidence IEA] AKAW2_30774A COG:K; EggNog:ENOG410PMXX; InterPro:IPR036236,IPR013087; PFAM:PF00096,PF13912 AKAW2_30775A COG:C; EggNog:ENOG410PHVT; InterPro:IPR023210,IPR036812; PFAM:PF00248 AKAW2_30776A SECRETED:SignalP(1-24) AKAW2_30777S COG:K; EggNog:ENOG410PRG6; InterPro:IPR036236,IPR013087; PFAM:PF00096 AKAW2_30778S COG:S; EggNog:ENOG410PQ58 AKAW2_30779A COG:S; EggNog:ENOG410PHZ9; InterPro:IPR015915; TransMembrane:1 (o367-389i); go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_30781A COG:S; EggNog:ENOG410PJ95; InterPro:IPR043129 AKAW2_30782A COG:S; EggNog:ENOG410PJ95; InterPro:IPR043129 AKAW2_30785A COG:S; EggNog:ENOG410PJ95; InterPro:IPR043129 AKAW2_30786S COG:S; EggNog:ENOG410PX2B AKAW2_30787A COG:A; EggNog:ENOG410PFU9; InterPro:IPR013026,IPR003107,IPR011990,IPR019734; PFAM:PF02184; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0006396 - RNA processing [Evidence IEA] AKAW2_30788S BUSCO:EOG09264B2X; COG:A; EggNog:ENOG410PI6D; InterPro:IPR012976,IPR027105,IPR002687,IPR019175, IPR036070,IPR029012,IPR042239; PFAM:PF01798,PF09785; go_component: GO:0046540 - U4/U6 x U5 tri-snRNP complex [Evidence IEA]; go_process: GO:0000244 - spliceosomal tri-snRNP complex assembly [Evidence IEA]; go_process: GO:0000398 - mRNA splicing, via spliceosome [Evidence IEA] AKAW2_30789S COG:S; EggNog:ENOG410PQDT AKAW2_30790S COG:S; EggNog:ENOG410PU92; InterPro:IPR008775; PFAM:PF05721 AKAW2_30791A InterPro:IPR036574; SECRETED:SignalP(1-20) AKAW2_30792S BUSCO:EOG09262LYR; COG:H; EggNog:ENOG410PG05; InterPro:IPR020082,IPR000043,IPR036291,IPR042172, IPR015878; PFAM:PF02826,PF00670; go_function: GO:0004013 - adenosylhomocysteinase activity [Evidence IEA] AKAW2_30793A COG:S; EggNog:ENOG410PGVD; InterPro:IPR009215,IPR015813,IPR013785; PFAM:PF09370; go_function: GO:0003824 - catalytic activity [Evidence IEA] AKAW2_30794S COG:S; EggNog:ENOG410PKND; InterPro:IPR044122,IPR008322; PFAM:PF06792 AKAW2_30795S COG:Q; EggNog:ENOG410PKNS; InterPro:IPR002347,IPR036291,IPR020904; PFAM:PF00106,PF13561,PF08659; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_30796S COG:K; EggNog:ENOG410Q2P7; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172; TransMembrane:1 (o576-597i); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_30797A COG:Q; EggNog:ENOG410PIQH; InterPro:IPR001613,IPR036188,IPR002937; PFAM:PF13450,PF01266; SECRETED:SignalP(1-18); go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_30798A CAZy:GH43; COG:G; EggNog:ENOG410PHGC; InterPro:IPR023296,IPR006710,IPR041542,IPR013320; PFAM:PF17851,PF04616; SECRETED:SignalP(1-18); go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_30799S COG:S; EggNog:ENOG410PTDP AKAW2_30800A COG:K; EggNog:ENOG410Q0CM; InterPro:IPR036236,IPR013087; PFAM:PF00096,PF12874,PF13912 AKAW2_30801S COG:S; EggNog:ENOG410PSMK AKAW2_30802A COG:A; EggNog:ENOG410PHNK; InterPro:IPR027417,IPR001650,IPR014014,IPR014001, IPR011545,IPR000629; PFAM:PF00270,PF00271; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0004386 - helicase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA] AKAW2_30803S COG:B; EggNog:ENOG410PQQB; InterPro:IPR009071,IPR036910; PFAM:PF00505,PF09011 AKAW2_30804S COG:S; EggNog:ENOG410PTXR AKAW2_30805A COG:J; EggNog:ENOG410PJE2; InterPro:IPR027524,IPR037518,IPR000555; MEROPS:MER0021886; PFAM:PF01398; go_component: GO:0005737 - cytoplasm [Evidence IEA]; go_component: GO:0005852 - eukaryotic translation initiation factor 3 complex [Evidence IEA]; go_function: GO:0003743 - translation initiation factor activity [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_function: GO:0008237 - metallopeptidase activity [Evidence IEA]; go_function: GO:0070122 - isopeptidase activity [Evidence IEA] AKAW2_30806S COG:E; EggNog:ENOG410PPKB; InterPro:IPR027519,IPR029058; go_function: GO:0004061 - arylformamidase activity [Evidence IEA]; go_process: GO:0019441 - tryptophan catabolic process to kynurenine [Evidence IEA] AKAW2_30807A COG:D,K,T; EggNog:ENOG410PG73; InterPro:IPR000704,IPR016149,IPR035991; PFAM:PF01214; go_component: GO:0005956 - protein kinase CK2 complex [Evidence IEA]; go_function: GO:0019887 - protein kinase regulator activity [Evidence IEA] AKAW2_30808A CAZy:GH6; COG:G; EggNog:ENOG410PGYJ; InterPro:IPR036434,IPR001524,IPR016288; PFAM:PF01341; SECRETED:SignalP(1-23); go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA]; go_process: GO:0030245 - cellulose catabolic process [Evidence IEA] AKAW2_30809A COG:S; EggNog:ENOG410PFXT; InterPro:IPR038816; go_function: GO:0070628 - proteasome binding [Evidence IEA] AKAW2_30810A COG:C; EggNog:ENOG410Q8RZ; InterPro:IPR018170,IPR020471,IPR036812,IPR023210; PFAM:PF00248; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_30811S COG:S; EggNog:ENOG410PQF7; InterPro:IPR019331,IPR039845; PFAM:PF10187 AKAW2_30812A COG:G; EggNog:ENOG410PK6R; InterPro:IPR005829,IPR005828,IPR003663,IPR036259, IPR020846; PFAM:PF00083,PF07690; TransMembrane:12 (i7-25o48-67i79-97o103-124i144-164o176-193i262-283o303- 320i327-348o360-386i398-420o426-447i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_30813S CAZy:GH51; COG:G; EggNog:ENOG410PIZK; InterPro:IPR010720,IPR017853,IPR013780; PFAM:PF06964; go_function: GO:0046556 - alpha-L-arabinofuranosidase activity [Evidence IEA]; go_process: GO:0046373 - L-arabinose metabolic process [Evidence IEA] AKAW2_30814A COG:S; EggNog:ENOG410PSQR; InterPro:IPR021719; PFAM:PF11720 AKAW2_30815S COG:S; EggNog:ENOG410Q2HW; TransMembrane:1 (o126-148i) AKAW2_30816A COG:S; EggNog:ENOG410PHZ6; InterPro:IPR027267,IPR037191,IPR002110,IPR020683, IPR003123,IPR036770,IPR001683,IPR036871; PFAM:PF00787,PF02204,PF13857; go_function: GO:0005515 - protein binding [Evidence IEA]; go_function: GO:0035091 - phosphatidylinositol binding [Evidence IEA] AKAW2_30817A BUSCO:EOG092654QZ; COG:J; EggNog:ENOG410PQ9W; InterPro:IPR036967,IPR001971; PFAM:PF00411; go_component: GO:0005840 - ribosome [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_process: GO:0006412 - translation [Evidence IEA] AKAW2_30818S BUSCO:EOG09262ESR; COG:U; EggNog:ENOG410PFS6; InterPro:IPR039544,IPR032710,IPR007379; PFAM:PF04280 AKAW2_30819A COG:S; EggNog:ENOG410PH4Z; InterPro:IPR011990,IPR032374,IPR019734,IPR006636, IPR013026; PFAM:PF13176,PF13181,PF16546,PF13414; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_30820S COG:D,K,T; EggNog:ENOG410PG79; InterPro:IPR009771,IPR036322,IPR040096; PFAM:PF07064; go_component: GO:0034066 - RIC1-RGP1 guanyl-nucleotide exchange factor complex [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0006886 - intracellular protein transport [Evidence IEA] AKAW2_30821A BUSCO:EOG09264RQY; COG:J; EggNog:ENOG410PGCQ; InterPro:IPR036974,IPR016437,IPR015947,IPR041366, IPR004521,IPR002478; PFAM:PF17832,PF01472; go_function: GO:0003723 - RNA binding [Evidence IEA] AKAW2_30822A BUSCO:EOG09262JWJ; COG:J; EggNog:ENOG410PH3G; InterPro:IPR041706,IPR027417,IPR012675,IPR012676, IPR013029,IPR006073,IPR031167,IPR004396,IPR023192, IPR004095; PFAM:PF06071,PF01926; go_function: GO:0005525 - GTP binding [Evidence IEA] AKAW2_30823A BUSCO:EOG09260U6R; COG:B; EggNog:ENOG410PG3Q; InterPro:IPR036322,IPR019015,IPR015943,IPR011494, IPR001680,IPR031120,IPR017986; PFAM:PF07569,PF00400,PF09453; go_component: GO:0005634 - nucleus [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0006325 - chromatin organization [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_30824A COG:C; EggNog:ENOG410PFBB; InterPro:IPR001972,IPR001107,IPR036013,IPR032435; MEROPS:MER0192051; PFAM:PF01145,PF16200; go_component: GO:0016020 - membrane [Evidence IEA] AKAW2_30825A COG:J,O; EggNog:ENOG410PN86; InterPro:IPR006630,IPR036390,IPR036388; PFAM:PF05383 AKAW2_30826A COG:S; EggNog:ENOG410PKKI; InterPro:IPR005365; PFAM:PF03666; go_process: GO:0032007 - negative regulation of TOR signaling [Evidence IEA]; go_process: GO:0034198 - cellular response to amino acid starvation [Evidence IEA] AKAW2_30827A COG:C; EggNog:ENOG410PRY2 AKAW2_30828S COG:S; EggNog:ENOG410PNV2; InterPro:IPR011057,IPR006913; PFAM:PF04828; go_function: GO:0016846 - carbon-sulfur lyase activity [Evidence IEA] AKAW2_30829S COG:C; EggNog:ENOG410PMDV; InterPro:IPR018170,IPR020471,IPR036812,IPR023210; PFAM:PF00248; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_30830S COG:I; EggNog:ENOG410PHHB; InterPro:IPR036938,IPR043216,IPR000326; PFAM:PF01569; TransMembrane:6 (i28-49o80-108i129-149o227-250i271-293o299-317i); go_function: GO:0008195 - phosphatidate phosphatase activity [Evidence IEA]; go_process: GO:0006644 - phospholipid metabolic process [Evidence IEA] AKAW2_30831A COG:S; EggNog:ENOG410PNCT; InterPro:IPR009851,IPR037202; PFAM:PF07200 AKAW2_30832A BUSCO:EOG09265313; COG:S; EggNog:ENOG410PK1D; InterPro:IPR002110,IPR036770,IPR020683; PFAM:PF12796,PF13857,PF13637,PF13606; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_30833S BUSCO:EOG09261IBJ; COG:J; EggNog:ENOG410PGIQ; InterPro:IPR027417,IPR015965,IPR015966,IPR012387, IPR019039; PFAM:PF08303,PF09511,PF08302; go_function: GO:0003972 - RNA ligase (ATP) activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0008081 - phosphoric diester hydrolase activity [Evidence IEA]; go_function: GO:0051730 - GTP-dependent polyribonucleotide 5'-hydroxyl-kinase activity [Evidence IEA]; go_process: GO:0006388 - tRNA splicing, via endonucleolytic cleavage and ligation [Evidence IEA] AKAW2_30834A COG:K; EggNog:ENOG410PQG0; InterPro:IPR036864,IPR021858,IPR001138; PFAM:PF00172,PF11951; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_30835A InterPro:IPR032675 AKAW2_30836S CAZy:CE3; COG:S; EggNog:ENOG410PKDM; InterPro:IPR013830,IPR036514; PFAM:PF13472; SECRETED:SignalP(1-39) AKAW2_30837A COG:S; EggNog:ENOG410PNAE; InterPro:IPR029063 AKAW2_30838S COG:E; EggNog:ENOG410PVBD; InterPro:IPR019996,IPR005801,IPR015890; PFAM:PF00425; go_function: GO:0008909 - isochorismate synthase activity [Evidence IEA]; go_function: GO:0016833 - oxo-acid-lyase activity [Evidence IEA]; go_process: GO:0009058 - biosynthetic process [Evidence IEA] AKAW2_30839A COG:U; EggNog:ENOG410PHP2; InterPro:IPR011691,IPR007305; PFAM:PF04178; TransMembrane:3 (o83-107i114-132o152-177i); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_process: GO:0016192 - vesicle-mediated transport [Evidence IEA] AKAW2_30841S COG:K; EggNog:ENOG410PIT3; InterPro:IPR011598,IPR036638; PFAM:PF00010; go_function: GO:0046983 - protein dimerization activity [Evidence IEA] AKAW2_30842A COG:C; EggNog:ENOG410PGWQ; InterPro:IPR018108,IPR023395,IPR002067; TransMembrane:1 (o225-243i); go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_30844A COG:S; EggNog:ENOG410PP9T; SECRETED:SignalP(1-21) AKAW2_30843S COG:T; EggNog:ENOG410PW8S; InterPro:IPR000719,IPR011009; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_30845A COG:Q; EggNog:ENOG410PM61; InterPro:IPR001128,IPR002401,IPR036396; PFAM:PF00067; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_30846A COG:S; EggNog:ENOG410PNZY; InterPro:IPR011009,IPR002575; PFAM:PF01636 AKAW2_30847A COG:E; EggNog:ENOG410PGSZ; InterPro:IPR002821,IPR008040,IPR003692; PFAM:PF01968,PF05378,PF02538; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_30848S COG:G; EggNog:ENOG410QDIM; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i69-95o107-126i138-159o165-185i197-216o228-248i297- 320o326-349i361-379o391-409i421-442o454-474i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_30849S COG:E; EggNog:ENOG410PVRG; InterPro:IPR006076,IPR036188; PFAM:PF01266,PF13450; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_30850A COG:S; EggNog:ENOG410PY53; InterPro:IPR036864,IPR021858,IPR001138; PFAM:PF00172,PF11951; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_30852S COG:S; EggNog:ENOG410PIT6; InterPro:IPR001279,IPR036866; PFAM:PF13483,PF12706 AKAW2_30853S TransMembrane:1 (i101-120o) AKAW2_30854S COG:H; EggNog:ENOG410PFP6; InterPro:IPR014746,IPR004308; PFAM:PF03074; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0004357 - glutamate-cysteine ligase activity [Evidence IEA]; go_process: GO:0006750 - glutathione biosynthetic process [Evidence IEA] AKAW2_30856A COG:G; EggNog:ENOG410PFE6; InterPro:IPR020846,IPR036259; TransMembrane:2 (i43-64o84-101i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA] AKAW2_30857S COG:S; EggNog:ENOG410PURU; InterPro:IPR036291,IPR008030; PFAM:PF13460,PF05368 AKAW2_30858S COG:S; EggNog:ENOG410PYCC; TransMembrane:5 (i36-58o70-89i96-115o156-177i591-614o) AKAW2_30859A BUSCO:EOG09261I1I; COG:S; EggNog:ENOG410PI71; InterPro:IPR022782,IPR005613; PFAM:PF03915; go_function: GO:0005519 - cytoskeletal regulatory protein binding [Evidence IEA]; go_process: GO:0051125 - regulation of actin nucleation [Evidence IEA] AKAW2_30860S BUSCO:EOG09262HQM; COG:A; EggNog:ENOG410PG74; InterPro:IPR025852,IPR009604; PFAM:PF14438,PF06741 AKAW2_30861S COG:T; EggNog:ENOG410PHPR; InterPro:IPR016024,IPR011989,IPR000719,IPR011009, IPR032682; PFAM:PF12717,PF07714,PF00069; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_30862S COG:S; EggNog:ENOG410PQP6 AKAW2_30863A COG:S; EggNog:ENOG410PHRH; InterPro:IPR000182,IPR016181; PFAM:PF13673,PF08445,PF00583; go_function: GO:0008080 - N-acetyltransferase activity [Evidence IEA] AKAW2_30864A COG:S; EggNog:ENOG410PIPE; InterPro:IPR017946; SECRETED:SignalP(1-20); TransMembrane:1 (n3-13c20/21o437-457i); go_function: GO:0008081 - phosphoric diester hydrolase activity [Evidence IEA]; go_process: GO:0006629 - lipid metabolic process [Evidence IEA] AKAW2_30865S COG:S; EggNog:ENOG410PNEM; InterPro:IPR009571; PFAM:PF06687; TransMembrane:5 (i28-50o125-143i155-178o212-237i258-278o); go_component: GO:0005886 - plasma membrane [Evidence IEA] AKAW2_30866A BUSCO:EOG092638XA; COG:S; EggNog:ENOG410PIRV; InterPro:IPR011047,IPR037588,IPR015943,IPR001680, IPR019775,IPR020472,IPR017986; PFAM:PF00400; go_component: GO:0031931 - TORC1 complex [Evidence IEA]; go_component: GO:0031932 - TORC2 complex [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0031929 - TOR signaling [Evidence IEA] AKAW2_30867S COG:S; EggNog:ENOG410Q29D AKAW2_30868A COG:N; EggNog:ENOG410PQRI; InterPro:IPR038586,IPR005334; PFAM:PF03645 AKAW2_30869A COG:S; EggNog:ENOG410PWUD; InterPro:IPR011009,IPR002575; PFAM:PF01636 AKAW2_30871A COG:O; EggNog:ENOG410PUK6; InterPro:IPR036249,IPR040079,IPR036282,IPR010987, IPR004045,IPR004046; PFAM:PF13409,PF00043,PF14497,PF13417,PF02798; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0006749 - glutathione metabolic process [Evidence IEA] AKAW2_30872S BUSCO:EOG09265IBC; COG:P; EggNog:ENOG410PPYS; InterPro:IPR003807; PFAM:PF02656; TransMembrane:3 (o33-53i60-82o102-121i) AKAW2_30873A CAZy:GH5; COG:G; EggNog:ENOG410PW79; InterPro:IPR017853,IPR001547; PFAM:PF00150; SECRETED:SignalP(1-19); go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_process: GO:0071704 - organic substance metabolic process [Evidence IEA] AKAW2_30874S COG:S; EggNog:ENOG410PFSY; InterPro:IPR037807; go_component: GO:0005671 - Ada2/Gcn5/Ada3 transcription activator complex [Evidence IEA] AKAW2_30875S COG:S; EggNog:ENOG410PNY6 AKAW2_30876S COG:S; EggNog:ENOG410PHWY; InterPro:IPR039535; PFAM:PF05935,PF14269; SECRETED:SignalP(1-17); TransMembrane:1 (n3-14c19/20o521-541i) AKAW2_30877A COG:S; EggNog:ENOG410PTEY; SECRETED:SignalP(1-21) AKAW2_30878A COG:O; EggNog:ENOG410PH9A; InterPro:IPR035983,IPR024928,IPR036020,IPR000569, IPR001202,IPR035892,IPR000008; PFAM:PF00397,PF00632; go_function: GO:0004842 - ubiquitin-protein transferase activity [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_function: GO:0061630 - ubiquitin protein ligase activity [Evidence IEA]; go_process: GO:0006511 - ubiquitin-dependent protein catabolic process [Evidence IEA] AKAW2_30879A COG:A; EggNog:ENOG410PPMX; InterPro:IPR000504,IPR012677,IPR035979; PFAM:PF00076; go_function: GO:0003676 - nucleic acid binding [Evidence IEA] AKAW2_30880A BUSCO:EOG092640ZF; COG:U; EggNog:ENOG410PJ94; InterPro:IPR000979,IPR028661,IPR029052,IPR024654; PFAM:PF12850; go_component: GO:0030904 - retromer complex [Evidence IEA]; go_process: GO:0042147 - retrograde transport, endosome to Golgi [Evidence IEA] AKAW2_30881A COG:S; EggNog:ENOG410PHUH; InterPro:IPR031100,IPR005269; PFAM:PF03641 AKAW2_30882S COG:E; EggNog:ENOG410PGH0; InterPro:IPR024169,IPR015424,IPR000192,IPR020578, IPR015421,IPR015422; PFAM:PF00266; go_function: GO:0003824 - catalytic activity [Evidence IEA] AKAW2_30883A BUSCO:EOG09263F3I; COG:K; EggNog:ENOG410PFK9; InterPro:IPR036412,IPR011948,IPR023214,IPR004274; PFAM:PF03031; go_function: GO:0016791 - phosphatase activity [Evidence IEA] AKAW2_30884S COG:J; EggNog:ENOG410PIME; InterPro:IPR000649,IPR042529,IPR037171; PFAM:PF01008; TransMembrane:1 (o295-314i); go_process: GO:0044237 - cellular metabolic process [Evidence IEA] AKAW2_30885A COG:J; EggNog:ENOG410PMW1; InterPro:IPR006032,IPR012340,IPR005680; PFAM:PF00164; go_component: GO:0005840 - ribosome [Evidence IEA]; go_component: GO:0015935 - small ribosomal subunit [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_process: GO:0006412 - translation [Evidence IEA] AKAW2_30886S COG:S; EggNog:ENOG410PN9C; PFAM:PF17242 AKAW2_30887A COG:S; EggNog:ENOG410PPZZ; InterPro:IPR031463; PFAM:PF17050; TransMembrane:1 (o6-24i); go_component: GO:0044284 - mitochondrial crista junction [Evidence IEA]; go_component: GO:0061617 - MICOS complex [Evidence IEA]; go_process: GO:0042407 - cristae formation [Evidence IEA] AKAW2_30888S BUSCO:EOG09264MZ1; COG:J; EggNog:ENOG410PNH8; InterPro:IPR036373,IPR000456; PFAM:PF01196; go_component: GO:0005840 - ribosome [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_process: GO:0006412 - translation [Evidence IEA] AKAW2_30889A COG:S; EggNog:ENOG410PIFF; InterPro:IPR001374,IPR036867,IPR024771; PFAM:PF12752,PF01424; go_function: GO:0003676 - nucleic acid binding [Evidence IEA] AKAW2_30891A COG:S; EggNog:ENOG410PQDR; InterPro:IPR013169; PFAM:PF08315 AKAW2_30892S COG:S; EggNog:ENOG410PRNK; InterPro:IPR002885,IPR011990; PFAM:PF01535,PF13812; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_30893A COG:S; EggNog:ENOG410PRUR; InterPro:IPR009653; PFAM:PF06842; SECRETED:SignalP(1-24); TransMembrane:1 (n9-19c24/25o53-71i) AKAW2_30894S COG:K; EggNog:ENOG410PPQF; InterPro:IPR009072,IPR003195; PFAM:PF02269; go_function: GO:0046982 - protein heterodimerization activity [Evidence IEA]; go_process: GO:0006366 - transcription by RNA polymerase II [Evidence IEA] AKAW2_30895A COG:J; EggNog:ENOG410PJNU; InterPro:IPR024969,IPR037518,IPR027531,IPR000555; MEROPS:MER0030133; PFAM:PF13012,PF01398; go_component: GO:0005852 - eukaryotic translation initiation factor 3 complex [Evidence IEA]; go_function: GO:0003743 - translation initiation factor activity [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_function: GO:0008237 - metallopeptidase activity [Evidence IEA]; go_function: GO:0031369 - translation initiation factor binding [Evidence IEA]; go_function: GO:0070122 - isopeptidase activity [Evidence IEA]; go_process: GO:0006413 - translational initiation [Evidence IEA] AKAW2_30896S BUSCO:EOG09261XZ6; COG:J; EggNog:ENOG410PG4V; InterPro:IPR010678; PFAM:PF06862; go_component: GO:0005634 - nucleus [Evidence IEA] AKAW2_30897S COG:E,G; EggNog:ENOG410PFCV; InterPro:IPR000620; PFAM:PF00892; TransMembrane:10 (i94-114o126-147i159-178o190-208i220-238o258-280i292- 312o324-351i391-408o414-432i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA] AKAW2_30898S COG:S; EggNog:ENOG410Q021 AKAW2_30899A BUSCO:EOG09264I9J; COG:I; EggNog:ENOG410PHWJ; InterPro:IPR041723,IPR004821,IPR014729; PFAM:PF01467; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_process: GO:0009058 - biosynthetic process [Evidence IEA] AKAW2_30900A COG:T; EggNog:ENOG410PGQI; InterPro:IPR000222,IPR036457,IPR001932,IPR015655; PFAM:PF00481; go_function: GO:0004722 - protein serine/threonine phosphatase activity [Evidence IEA]; go_function: GO:0016791 - phosphatase activity [Evidence IEA]; go_function: GO:0043169 - cation binding [Evidence IEA]; go_process: GO:0006470 - protein dephosphorylation [Evidence IEA] AKAW2_30901A COG:U; EggNog:ENOG410PMZM; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i81-100o150-167i179-202o208-234i246-267o273-293i348- 371o383-402i422-440o446-466i478-502o514-534i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_30902A COG:S; EggNog:ENOG410PFMN; InterPro:IPR013783,IPR015919,IPR006644; PFAM:PF05345; SECRETED:SignalP(1-18); TransMembrane:1 (n3-15c27/28o435-457i); go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0005509 - calcium ion binding [Evidence IEA] AKAW2_30903A COG:S; EggNog:ENOG410QE17; InterPro:IPR016181,IPR000182; PFAM:PF13508,PF13673,PF08445,PF00583; go_function: GO:0008080 - N-acetyltransferase activity [Evidence IEA] AKAW2_30904S COG:Z; EggNog:ENOG410PS3P; InterPro:IPR022214; PFAM:PF12554; go_component: GO:0008274 - gamma-tubulin ring complex [Evidence IEA]; go_process: GO:0033566 - gamma-tubulin complex localization [Evidence IEA] AKAW2_30905A COG:O; EggNog:ENOG410PJY8; InterPro:IPR009060,IPR003892; PFAM:PF02845; go_function: GO:0005515 - protein binding [Evidence IEA]; go_function: GO:0043130 - ubiquitin binding [Evidence IEA] AKAW2_30906S COG:A; EggNog:ENOG410PG85; InterPro:IPR011709,IPR027417,IPR001650,IPR014001, IPR007502,IPR002464; PFAM:PF04408,PF07717,PF00271; go_function: GO:0004386 - helicase activity [Evidence IEA] AKAW2_30907S COG:O; EggNog:ENOG410PNU2; InterPro:IPR008979,IPR010400,IPR037047; PFAM:PF06201 AKAW2_30908A BUSCO:EOG09264IIZ; COG:U; EggNog:ENOG410PPFV; InterPro:IPR005024; PFAM:PF03357; go_process: GO:0007034 - vacuolar transport [Evidence IEA] AKAW2_30909S BUSCO:EOG09261YV6; COG:O; EggNog:ENOG410PHRK; InterPro:IPR041569,IPR003959,IPR027417,IPR003593, IPR003960; PFAM:PF00004,PF17862,PF05496,PF07724; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA] AKAW2_30910A BUSCO:EOG092612LP; COG:J; EggNog:ENOG410PGWN; InterPro:IPR036322,IPR015943,IPR019775,IPR028598, IPR001680,IPR012953,IPR017986; PFAM:PF08145,PF00400; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0006364 - rRNA processing [Evidence IEA]; go_process: GO:0042254 - ribosome biogenesis [Evidence IEA] AKAW2_30911S COG:S; EggNog:ENOG410PSCT; InterPro:IPR036864,IPR001138; PFAM:PF00172; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_30912A COG:S; EggNog:ENOG410PR7S; InterPro:IPR007149; PFAM:PF04004; go_component: GO:0016593 - Cdc73/Paf1 complex [Evidence IEA]; go_process: GO:0006368 - transcription elongation from RNA polymerase II promoter [Evidence IEA]; go_process: GO:0016570 - histone modification [Evidence IEA] AKAW2_30913S COG:D; EggNog:ENOG410PJTW; InterPro:IPR005301,IPR036703; PFAM:PF03637 AKAW2_30914A COG:S; EggNog:ENOG410PTSC; InterPro:IPR038966; go_process: GO:0070682 - proteasome regulatory particle assembly [Evidence IEA] AKAW2_30915S COG:T; EggNog:ENOG410PNV5; InterPro:IPR022764,IPR035952; MEROPS:MER0015472; PFAM:PF01694; TransMembrane:6 (i329-347o367-386i446-465o471-492i513-530o542-558i); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0004252 - serine-type endopeptidase activity [Evidence IEA] AKAW2_30916S COG:S; EggNog:ENOG410Q22D AKAW2_30917S COG:S; EggNog:ENOG410QE3V; InterPro:IPR018946,IPR043904 AKAW2_30918S COG:E; EggNog:ENOG410PHFY; InterPro:IPR002293; PFAM:PF00324,PF13520; TransMembrane:14 (i73-90o105-129i141-162o168-187i199-220o226-248i269- 293o305-323i335-352o358-385i406-428o434-458i470-489o509- 527i); go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_30919A COG:I; EggNog:ENOG410PG8A; InterPro:IPR021771,IPR016035,IPR002641; PFAM:PF11815,PF01734; TransMembrane:2 (o6-25i208-228o); go_function: GO:0004806 - triglyceride lipase activity [Evidence IEA]; go_process: GO:0006629 - lipid metabolic process [Evidence IEA] AKAW2_30920A COG:J; EggNog:ENOG410PI94; InterPro:IPR002359,IPR036789,IPR000702,IPR020040; PFAM:PF00347; go_component: GO:0005840 - ribosome [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_function: GO:0019843 - rRNA binding [Evidence IEA]; go_process: GO:0006412 - translation [Evidence IEA] AKAW2_30921A COG:O; EggNog:ENOG410PN7D; InterPro:IPR011899,IPR014025,IPR036249,IPR002109; PFAM:PF00462; TransMembrane:1 (i7-25o); go_function: GO:0015035 - protein disulfide oxidoreductase activity [Evidence IEA] AKAW2_30922A COG:S; EggNog:ENOG410PI1R; InterPro:IPR000073,IPR029058; PFAM:PF12697,PF00561; TransMembrane:1 (o539-558i) AKAW2_30924S COG:S; EggNog:ENOG410PKGT; InterPro:IPR021773,IPR012880; PFAM:PF07919 AKAW2_30925S COG:S; EggNog:ENOG410PMZ0; InterPro:IPR039602,IPR013904; PFAM:PF08595; go_process: GO:0016575 - histone deacetylation [Evidence IEA] AKAW2_30926A BUSCO:EOG0926425H; COG:I; EggNog:ENOG410PNCF; InterPro:IPR007318,IPR024960; PFAM:PF04191; TransMembrane:3 (o15-33i45-66o86-108i); go_function: GO:0008757 - S-adenosylmethionine-dependent methyltransferase activity [Evidence IEA]; go_process: GO:0006656 - phosphatidylcholine biosynthetic process [Evidence IEA] AKAW2_30927S COG:D,U,Z; EggNog:ENOG410Q179; InterPro:IPR036305,IPR016137,IPR001683,IPR003114, IPR036871,IPR013937; PFAM:PF02194,PF08628,PF00615,PF00787; TransMembrane:3 (i7-26o32-55i256-274o); go_function: GO:0035091 - phosphatidylinositol binding [Evidence IEA] AKAW2_30928A COG:S; EggNog:ENOG410PNFK AKAW2_30929S COG:A; EggNog:ENOG410PGB1; InterPro:IPR036322,IPR037631,IPR015943,IPR001680, IPR020472,IPR017986; PFAM:PF00400; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0006406 - mRNA export from nucleus [Evidence IEA] AKAW2_30930A BUSCO:EOG09260TUT; COG:J; EggNog:ENOG410PG5D; InterPro:IPR041872,IPR009080,IPR014758,IPR001412, IPR029038,IPR033911,IPR015413,IPR014729; PFAM:PF09334; go_function: GO:0000166 - nucleotide binding [Evidence IEA]; go_function: GO:0004812 - aminoacyl-tRNA ligase activity [Evidence IEA]; go_function: GO:0004825 - methionine-tRNA ligase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006418 - tRNA aminoacylation for protein translation [Evidence IEA]; go_process: GO:0006431 - methionyl-tRNA aminoacylation [Evidence IEA] AKAW2_30931S COG:S; EggNog:ENOG410PRAF; InterPro:IPR019191; PFAM:PF09811 AKAW2_30932S COG:G; EggNog:ENOG410Q2QX; InterPro:IPR011042,IPR013658; SECRETED:SignalP(1-18) AKAW2_30933A BUSCO:EOG0926347K; COG:K,O; EggNog:ENOG410PGRJ; InterPro:IPR003226; PFAM:PF03690 AKAW2_30934S BUSCO:EOG092640ET; COG:S; EggNog:ENOG410PIH0; InterPro:IPR013635; PFAM:PF08426; SECRETED:SignalP(1-18); TransMembrane:9 (n6-17c23/24o33-51i63-83o140-160i172-193o205-224i236- 253o273-291i298-319o357-378i) AKAW2_30935A COG:T,U; EggNog:ENOG410PQSG; InterPro:IPR006760; PFAM:PF04667 AKAW2_30936S COG:S; EggNog:ENOG410PHK1; InterPro:IPR007364; PFAM:PF04252; go_function: GO:0008168 - methyltransferase activity [Evidence IEA] AKAW2_30937S BUSCO:EOG092623WR; COG:O; EggNog:ENOG410PGB2; InterPro:IPR018202,IPR001563,IPR033124,IPR029058; MEROPS:MER0000413; PFAM:PF00450; SECRETED:SignalP(1-34); TransMembrane:1 (n17-27c34/35o522-539i); go_function: GO:0004185 - serine-type carboxypeptidase activity [Evidence IEA]; go_process: GO:0006508 - proteolysis [Evidence IEA] AKAW2_30938A COG:S; EggNog:ENOG410PHHC; InterPro:IPR036322,IPR001680,IPR020472,IPR028608, IPR017986; PFAM:PF00400; go_component: GO:0097361 - CIA complex [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0016226 - iron-sulfur cluster assembly [Evidence IEA] AKAW2_30939A COG:T; EggNog:ENOG410PJ8P; InterPro:IPR008862; PFAM:PF05794 AKAW2_30940A COG:O; EggNog:ENOG410PJ32; InterPro:IPR001841,IPR017921,IPR008913,IPR037275, IPR039512,IPR037274,IPR013083; PFAM:PF05495,PF14599,PF13639; go_function: GO:0008270 - zinc ion binding [Evidence IEA] AKAW2_30941A COG:S; EggNog:ENOG410PRXG AKAW2_30942S COG:S; EggNog:ENOG410PI5C; InterPro:IPR018744; PFAM:PF10056 AKAW2_30943A COG:P; EggNog:ENOG410PRUT; InterPro:IPR006121,IPR036163,IPR017969; PFAM:PF00403; go_function: GO:0046872 - metal ion binding [Evidence IEA]; go_process: GO:0030001 - metal ion transport [Evidence IEA] AKAW2_30944A COG:S; EggNog:ENOG410PPF1; InterPro:IPR019350; PFAM:PF10214 AKAW2_30945S COG:S; EggNog:ENOG410PHDK; InterPro:IPR013255; PFAM:PF08234 AKAW2_30946A COG:J; EggNog:ENOG410QE47; InterPro:IPR036322,IPR015943,IPR019775,IPR001680, IPR017986; PFAM:PF00400; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_30947A COG:J; EggNog:ENOG410PRG1; InterPro:IPR011332,IPR002677; PFAM:PF01783; TransMembrane:1 (n10-22c27/28o43-64i); go_component: GO:0015934 - large ribosomal subunit [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_process: GO:0006412 - translation [Evidence IEA] AKAW2_30948S COG:D,T,Z; EggNog:ENOG410Q7XG; InterPro:IPR030379,IPR027417,IPR016491; PFAM:PF00735,PF01926; go_function: GO:0005525 - GTP binding [Evidence IEA] AKAW2_30949A COG:F; EggNog:ENOG410PHNN; InterPro:IPR027417,IPR008145,IPR008144,IPR020590, IPR017665; PFAM:PF00625; go_function: GO:0004385 - guanylate kinase activity [Evidence IEA]; go_process: GO:0006163 - purine nucleotide metabolic process [Evidence IEA] AKAW2_30950A BUSCO:EOG09263CUQ; COG:U; EggNog:ENOG410PH5H; InterPro:IPR019459,IPR000237; PFAM:PF10375 AKAW2_30951A BUSCO:EOG09264XYD; COG:S; EggNog:ENOG410PFVC; InterPro:IPR008532,IPR039730; PFAM:PF05670 AKAW2_30952S COG:S; EggNog:ENOG410PRPQ AKAW2_30953A COG:C; EggNog:ENOG410PGEG; InterPro:IPR031656,IPR036188,IPR006076,IPR000447, IPR038299; PFAM:PF01266,PF16901; TransMembrane:1 (i12-31o); go_component: GO:0009331 - glycerol-3-phosphate dehydrogenase complex [Evidence IEA]; go_function: GO:0004368 - glycerol-3-phosphate dehydrogenase (quinone) activity [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0006072 - glycerol-3-phosphate metabolic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_30954S COG:Q; EggNog:ENOG410PKYU; InterPro:IPR001128,IPR002401,IPR036396; PFAM:PF00067; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_30955A COG:S; EggNog:ENOG410Q0T0; InterPro:IPR024368; PFAM:PF12855 AKAW2_30956A COG:S; EggNog:ENOG410PREG; InterPro:IPR013963; PFAM:PF08654; go_component: GO:0042729 - DASH complex [Evidence IEA]; go_component: GO:0072686 - mitotic spindle [Evidence IEA]; go_process: GO:0000278 - mitotic cell cycle [Evidence IEA] AKAW2_30957S COG:S; EggNog:ENOG410PRS3; InterPro:IPR038889,IPR011515,IPR011516; PFAM:PF07558,PF07557; go_component: GO:0000775 - chromosome, centromeric region [Evidence IEA]; go_component: GO:0005634 - nucleus [Evidence IEA]; go_process: GO:0045132 - meiotic chromosome segregation [Evidence IEA] AKAW2_30958A COG:S; EggNog:ENOG410PSAD; InterPro:IPR011107; PFAM:PF07491; go_function: GO:0004865 - protein serine/threonine phosphatase inhibitor activity [Evidence IEA]; go_process: GO:0032515 - negative regulation of phosphoprotein phosphatase activity [Evidence IEA] AKAW2_30959A BUSCO:EOG09260ABY; COG:U,Y; EggNog:ENOG410PI0K; InterPro:IPR016024,IPR011989,IPR014877,IPR040485, IPR041235,IPR001494,IPR041123,IPR013598; PFAM:PF18784,PF03810,PF08389,PF18777,PF08767, PF18787; TransMembrane:1 (i301-320o); go_function: GO:0005049 - nuclear export signal receptor activity [Evidence IEA]; go_function: GO:0008536 - Ran GTPase binding [Evidence IEA]; go_process: GO:0006886 - intracellular protein transport [Evidence IEA] AKAW2_30960S COG:E; EggNog:ENOG410PHH7; InterPro:IPR024688,IPR036864,IPR011004,IPR001451, IPR001138; PFAM:PF00172,PF14602,PF00132,PF16628,PF12464; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_function: GO:0016407 - acetyltransferase activity [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_30961A BUSCO:EOG092630N3; COG:H; EggNog:ENOG410PFRX; InterPro:IPR030656,IPR001731,IPR013785; PFAM:PF00490; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0004655 - porphobilinogen synthase activity [Evidence IEA]; go_function: GO:0046872 - metal ion binding [Evidence IEA]; go_process: GO:0033014 - tetrapyrrole biosynthetic process [Evidence IEA] AKAW2_30962A COG:J; EggNog:ENOG410PFRZ; InterPro:IPR042529,IPR011559,IPR005251,IPR000649, IPR037171; PFAM:PF01008; go_process: GO:0044237 - cellular metabolic process [Evidence IEA]; go_process: GO:0044249 - cellular biosynthetic process [Evidence IEA] AKAW2_30963A COG:A; EggNog:ENOG410PRHI; InterPro:IPR016487,IPR010920,IPR001163; PFAM:PF01423; go_component: GO:0005732 - small nucleolar ribonucleoprotein complex [Evidence IEA]; go_process: GO:0000398 - mRNA splicing, via spliceosome [Evidence IEA] AKAW2_30964S COG:O; EggNog:ENOG410PNMD; InterPro:IPR029071,IPR000626,IPR022617; PFAM:PF00240,PF11976; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_30965S BUSCO:EOG09265F2Y; COG:S; EggNog:ENOG410PPKG; InterPro:IPR039127,IPR005651; PFAM:PF03966; go_function: GO:0046982 - protein heterodimerization activity [Evidence IEA] AKAW2_30966A BUSCO:EOG09264CH7; COG:B; EggNog:ENOG410PH74; InterPro:IPR035979,IPR001214,IPR024636,IPR010916, IPR012677,IPR024657,IPR003616,IPR017111; PFAM:PF11767,PF11764,PF00856; go_component: GO:0048188 - Set1C/COMPASS complex [Evidence IEA]; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_function: GO:0018024 - histone-lysine N-methyltransferase activity [Evidence IEA]; go_process: GO:0034968 - histone lysine methylation [Evidence IEA] AKAW2_30967S BUSCO:EOG09260SRF; COG:M; EggNog:ENOG410PG0E; InterPro:IPR035466,IPR029055,IPR017932,IPR035490, IPR001347; MEROPS:MER0012158; PFAM:PF13522,PF01380,PF13537; go_function: GO:0097367 - carbohydrate derivative binding [Evidence IEA]; go_process: GO:1901135 - carbohydrate derivative metabolic process [Evidence IEA] AKAW2_30968S BUSCO:EOG09264OYZ; COG:H; EggNog:ENOG410PMH7; InterPro:IPR036467,IPR034964,IPR002180; PFAM:PF00885; go_component: GO:0009349 - riboflavin synthase complex [Evidence IEA]; go_function: GO:0000906 - 6,7-dimethyl-8-ribityllumazine synthase activity [Evidence IEA]; go_process: GO:0009231 - riboflavin biosynthetic process [Evidence IEA] AKAW2_30969A BUSCO:EOG092644WX; COG:O; EggNog:ENOG410PGK8; InterPro:IPR029055,IPR001353,IPR023332,IPR037555, IPR000426; MEROPS:MER0000553; PFAM:PF00227,PF10584; go_component: GO:0005839 - proteasome core complex [Evidence IEA]; go_component: GO:0019773 - proteasome core complex, alpha-subunit complex [Evidence IEA]; go_process: GO:0006511 - ubiquitin-dependent protein catabolic process [Evidence IEA]; go_process: GO:0051603 - proteolysis involved in cellular protein catabolic process [Evidence IEA] AKAW2_30970S COG:S; EggNog:ENOG410PQ99 AKAW2_30971A COG:S; EggNog:ENOG410Q2WH; SECRETED:SignalP(1-18) AKAW2_30972S COG:E; EggNog:ENOG410PFT1; InterPro:IPR004434,IPR024084,IPR019818; PFAM:PF00180; go_function: GO:0000287 - magnesium ion binding [Evidence IEA]; go_function: GO:0004449 - isocitrate dehydrogenase (NAD+) activity [Evidence IEA]; go_function: GO:0016616 - oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Evidence IEA]; go_function: GO:0051287 - NAD binding [Evidence IEA]; go_process: GO:0006099 - tricarboxylic acid cycle [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_30973A BUSCO:EOG092646EZ; COG:Q; EggNog:ENOG410PGDN; InterPro:IPR039769,IPR029063,IPR022238,IPR013216; PFAM:PF13649,PF12589,PF08241; go_function: GO:0008168 - methyltransferase activity [Evidence IEA]; go_function: GO:0016435 - rRNA (guanine) methyltransferase activity [Evidence IEA]; go_process: GO:0070476 - rRNA (guanine-N7)-methylation [Evidence IEA] AKAW2_30974S COG:I,T; EggNog:ENOG410PN1G; InterPro:IPR007277; PFAM:PF04148; TransMembrane:5 (o6-30i44-61o67-84i96-112o145-164i); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0097020 - COPII receptor activity [Evidence IEA]; go_process: GO:0006888 - endoplasmic reticulum to Golgi vesicle-mediated transport [Evidence IEA] AKAW2_30975A COG:T; EggNog:ENOG410PFGB; InterPro:IPR011993,IPR000198,IPR008936,IPR001849; PFAM:PF00169,PF00620; go_process: GO:0007165 - signal transduction [Evidence IEA] AKAW2_30977A BUSCO:EOG092615Y4; COG:S; EggNog:ENOG410PFEP; InterPro:IPR012571; PFAM:PF08118; TransMembrane:3 (i135-152o158-179i600-620o); go_component: GO:0005743 - mitochondrial inner membrane [Evidence IEA]; go_process: GO:0000001 - mitochondrion inheritance [Evidence IEA]; go_process: GO:0007005 - mitochondrion organization [Evidence IEA] AKAW2_30978S BUSCO:EOG09264SQJ; COG:A; EggNog:ENOG410PG9H; InterPro:IPR039912,IPR036612; go_function: GO:0003723 - RNA binding [Evidence IEA] AKAW2_30979A BUSCO:EOG0926457R; COG:O; EggNog:ENOG410PHF4; InterPro:IPR035202,IPR029055,IPR001353,IPR023333; MEROPS:MER0005692; PFAM:PF00227; go_component: GO:0005839 - proteasome core complex [Evidence IEA]; go_function: GO:0004298 - threonine-type endopeptidase activity [Evidence IEA]; go_process: GO:0051603 - proteolysis involved in cellular protein catabolic process [Evidence IEA] AKAW2_30980S COG:S; EggNog:ENOG410PPRM; InterPro:IPR012479; PFAM:PF07818; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_30981S BUSCO:EOG09263XZN; COG:O; EggNog:ENOG410PGKS; InterPro:IPR029055,IPR001353,IPR023333,IPR016295, IPR016050; MEROPS:MER0001711; PFAM:PF00227; go_component: GO:0005839 - proteasome core complex [Evidence IEA]; go_function: GO:0004298 - threonine-type endopeptidase activity [Evidence IEA]; go_process: GO:0051603 - proteolysis involved in cellular protein catabolic process [Evidence IEA] AKAW2_30982A COG:Q; EggNog:ENOG410PGFE; InterPro:IPR011234,IPR036663; PFAM:PF01557; go_function: GO:0003824 - catalytic activity [Evidence IEA] AKAW2_30983S COG:O; EggNog:ENOG410PNWV; InterPro:IPR008978,IPR002068; PFAM:PF00011 AKAW2_30984A COG:S; EggNog:ENOG410Q1AA AKAW2_30985S COG:S; EggNog:ENOG410PRC9; InterPro:IPR007135; PFAM:PF03987 AKAW2_30986A COG:A; EggNog:ENOG410PN5A; InterPro:IPR000504,IPR012677,IPR035979; PFAM:PF00076; TransMembrane:3 (i12-29o35-56i103-121o); go_function: GO:0003676 - nucleic acid binding [Evidence IEA] AKAW2_30987S BUSCO:EOG09262VPD; COG:Z; EggNog:ENOG410PIRY; InterPro:IPR017383,IPR036322,IPR015943,IPR001680, IPR017986; PFAM:PF00400; go_component: GO:0005885 - Arp2/3 protein complex [Evidence IEA]; go_component: GO:0015629 - actin cytoskeleton [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0030833 - regulation of actin filament polymerization [Evidence IEA]; go_process: GO:0034314 - Arp2/3 complex-mediated actin nucleation [Evidence IEA] AKAW2_30988S COG:I; EggNog:ENOG410PK4T; InterPro:IPR002921,IPR029058; PFAM:PF01764; TransMembrane:1 (o6-28i); go_process: GO:0006629 - lipid metabolic process [Evidence IEA] AKAW2_30989A COG:S; EggNog:ENOG410PGSW; InterPro:IPR018946,IPR036020,IPR043904,IPR001202; PFAM:PF00397,PF19050; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_30990A COG:S; EggNog:ENOG410PRIW; InterPro:IPR021858; PFAM:PF11951 AKAW2_30992A COG:S; EggNog:ENOG410PH87; InterPro:IPR016024,IPR011989,IPR024372; PFAM:PF13001; go_function: GO:0060090 - molecular adaptor activity [Evidence IEA]; go_process: GO:0043248 - proteasome assembly [Evidence IEA] AKAW2_30993A BUSCO:EOG09260OE9; COG:L; EggNog:ENOG410PIC1; InterPro:IPR001841,IPR027417,IPR017907,IPR000330, IPR038718,IPR001650,IPR014001,IPR013083; PFAM:PF13923,PF00176,PF13920,PF00097,PF13639; go_function: GO:0005524 - ATP binding [Evidence IEA] AKAW2_30994A BUSCO:EOG09263YFH; COG:G; EggNog:ENOG410PHHP; InterPro:IPR043169,IPR006379,IPR005002,IPR036412, IPR023214; PFAM:PF03332; go_function: GO:0004615 - phosphomannomutase activity [Evidence IEA]; go_process: GO:0009298 - GDP-mannose biosynthetic process [Evidence IEA] AKAW2_30995A COG:O; EggNog:ENOG410PME1; InterPro:IPR001623,IPR036869; PFAM:PF00226 AKAW2_30996S COG:S; EggNog:ENOG410PRW1; TransMembrane:1 (i100-123o) AKAW2_30997A COG:O; EggNog:ENOG410QDG0; InterPro:IPR001623,IPR036869; PFAM:PF00226; SECRETED:SignalP(1-20); TransMembrane:1 (n4-14c18/19o166-187i) AKAW2_30998S COG:U; EggNog:ENOG410PMV2; InterPro:IPR004895; PFAM:PF03208; TransMembrane:3 (o69-99i120-136o142-159i) AKAW2_30999S COG:S; EggNog:ENOG410Q2KF AKAW2_31000S COG:S; EggNog:ENOG410PMH0; InterPro:IPR019402; PFAM:PF10277; TransMembrane:6 (i7-29o59-76i97-119o131-151i163-189o201-222i) AKAW2_31001A COG:S; EggNog:ENOG410PKQK; InterPro:IPR000387,IPR029021,IPR026893,IPR016130; go_function: GO:0004721 - phosphoprotein phosphatase activity [Evidence IEA]; go_function: GO:0004725 - protein tyrosine phosphatase activity [Evidence IEA]; go_function: GO:0016791 - phosphatase activity [Evidence IEA]; go_process: GO:0016311 - dephosphorylation [Evidence IEA] AKAW2_31002A COG:S; EggNog:ENOG410PI5Y; InterPro:IPR024527; PFAM:PF12757 AKAW2_31003S COG:S; EggNog:ENOG410Q1C2; InterPro:IPR038595,IPR025659,IPR007612; PFAM:PF04525 AKAW2_31004A COG:G; EggNog:ENOG410PHKP; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i70-98o104-123i135-153o165-188i200-218o224-244i350- 377o389-410i431-452o458-485i497-516o528-548i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_31005S COG:S; EggNog:ENOG410PT41; InterPro:IPR008427; PFAM:PF05730 AKAW2_31006A COG:S; EggNog:ENOG410Q0F9; InterPro:IPR018815; PFAM:PF10311; SECRETED:SignalP(1-27); TransMembrane:3 (n14-24c32/33o56-77i121-141o177-195i) AKAW2_31007S COG:O; EggNog:ENOG410PK7U; InterPro:IPR001330,IPR008930; PFAM:PF00432; go_function: GO:0003824 - catalytic activity [Evidence IEA] AKAW2_31008S COG:T; EggNog:ENOG410PIHI; InterPro:IPR017441,IPR008271,IPR000719,IPR011009; PFAM:PF07714,PF14531,PF00069; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_31009A COG:G; EggNog:ENOG410PFDQ; InterPro:IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i32-52o72-93i100-119o125-142i163-186o201-222i252-274o294- 311i318-336o342-365i377-397o403-427i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_31010A COG:P; EggNog:ENOG410PH09; InterPro:IPR006068,IPR018303,IPR023298,IPR023299, IPR005782,IPR001757,IPR004014,IPR036412,IPR008250, IPR023214; PFAM:PF00689,PF13246,PF00122,PF00690,PF00702; TransMembrane:10 (i61-78o84-103i256-276o288-317i754-775o787-806i827- 851o890-907i919-941o961-978i); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0000166 - nucleotide binding [Evidence IEA]; go_function: GO:0005388 - calcium transmembrane transporter activity, phosphorylative mechanism [Evidence IEA]; go_process: GO:0006816 - calcium ion transport [Evidence IEA] AKAW2_31011S COG:O; EggNog:ENOG410PHTI; InterPro:IPR023410,IPR000308,IPR036815,IPR023409; PFAM:PF00244 AKAW2_31012A COG:J; EggNog:ENOG410PNWK; InterPro:IPR013906,IPR023194; PFAM:PF08597; go_component: GO:0005737 - cytoplasm [Evidence IEA]; go_component: GO:0005852 - eukaryotic translation initiation factor 3 complex [Evidence IEA]; go_function: GO:0003743 - translation initiation factor activity [Evidence IEA] AKAW2_31013A COG:G; EggNog:ENOG410PFRB; InterPro:IPR036849,IPR000941,IPR020811,IPR020810, IPR020809,IPR029017; PFAM:PF03952,PF00113; go_component: GO:0000015 - phosphopyruvate hydratase complex [Evidence IEA]; go_function: GO:0000287 - magnesium ion binding [Evidence IEA]; go_function: GO:0004634 - phosphopyruvate hydratase activity [Evidence IEA]; go_process: GO:0006096 - glycolytic process [Evidence IEA] AKAW2_31014S COG:O; EggNog:ENOG410PG6Y; InterPro:IPR041569,IPR003960,IPR003959,IPR027417, IPR003593,IPR032501,IPR005937; PFAM:PF16450,PF00004,PF17862,PF07728,PF07724; go_component: GO:0005737 - cytoplasm [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016787 - hydrolase activity [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA]; go_process: GO:0030163 - protein catabolic process [Evidence IEA] AKAW2_31015S CAZy:GH47; COG:G; EggNog:ENOG410PFVB; InterPro:IPR036026,IPR001382; PFAM:PF01532; TransMembrane:1 (i82-99o); go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0004571 - mannosyl-oligosaccharide 1,2-alpha-mannosidase activity [Evidence IEA]; go_function: GO:0005509 - calcium ion binding [Evidence IEA] AKAW2_31016A COG:E; EggNog:ENOG410PH1I; InterPro:IPR001261,IPR002933,IPR011650,IPR036264; MEROPS:MER0026479; PFAM:PF01546,PF07687; SECRETED:SignalP(1-16); go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_31017S COG:S; EggNog:ENOG410PNR6 AKAW2_31018A COG:L; EggNog:ENOG410PG5A; InterPro:IPR027417,IPR013954,IPR006549,IPR006551, IPR036412,IPR023214; PFAM:PF08645 AKAW2_31019A COG:K; EggNog:ENOG410PT00; InterPro:IPR019095; PFAM:PF09637; go_component: GO:0016592 - mediator complex [Evidence IEA]; go_function: GO:0003712 - transcription coregulator activity [Evidence IEA]; go_process: GO:0006357 - regulation of transcription by RNA polymerase II [Evidence IEA] AKAW2_31020S COG:S; EggNog:ENOG410PRG5; InterPro:IPR020373; PFAM:PF10937 AKAW2_31021S COG:S; EggNog:ENOG410PKSI; InterPro:IPR006968; PFAM:PF04884; TransMembrane:1 (o259-279i) AKAW2_31022A COG:T; EggNog:ENOG410PPQJ; InterPro:IPR016137,IPR036305; PFAM:PF00615 AKAW2_31024A COG:T; EggNog:ENOG410PFDM; InterPro:IPR017441,IPR008271,IPR000719,IPR011009; PFAM:PF07714,PF00069; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_31025A COG:B; EggNog:ENOG410PH94; InterPro:IPR013719,IPR011993; PFAM:PF08512 AKAW2_31026A COG:S; EggNog:ENOG410PPQ3; InterPro:IPR003256,IPR008991,IPR041988,IPR014722; go_component: GO:0005840 - ribosome [Evidence IEA]; go_function: GO:0003723 - RNA binding [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_process: GO:0006412 - translation [Evidence IEA] AKAW2_31028S COG:S; EggNog:ENOG410PFAP; InterPro:IPR005225,IPR001806,IPR027417,IPR003578; PFAM:PF00025,PF08477,PF00071; go_function: GO:0003924 - GTPase activity [Evidence IEA]; go_function: GO:0005525 - GTP binding [Evidence IEA]; go_process: GO:0007264 - small GTPase mediated signal transduction [Evidence IEA] AKAW2_31029A COG:S; EggNog:ENOG410PKQJ; InterPro:IPR013176,IPR043987; PFAM:PF19031; go_component: GO:0035658 - Mon1-Ccz1 complex [Evidence IEA]; go_process: GO:0016192 - vesicle-mediated transport [Evidence IEA] AKAW2_31031S BUSCO:EOG092631ML; COG:J; EggNog:ENOG410PM37; InterPro:IPR002376,IPR041711,IPR036477; PFAM:PF00551; go_function: GO:0016742 - hydroxymethyl-, formyl-and related transferase activity [Evidence IEA]; go_process: GO:0009058 - biosynthetic process [Evidence IEA] AKAW2_31030A COG:Q; EggNog:ENOG410PJ9X; InterPro:IPR002347,IPR036291,IPR020904; PFAM:PF00106,PF13561,PF08659; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_31032A BUSCO:EOG092643QM; COG:G; EggNog:ENOG410PR2I; InterPro:IPR013969; PFAM:PF08660; TransMembrane:3 (o6-30i50-69o186-208i); go_process: GO:0006488 - dolichol-linked oligosaccharide biosynthetic process [Evidence IEA] AKAW2_31033S COG:S; EggNog:ENOG410PNY9; InterPro:IPR042321,IPR018617; PFAM:PF09779; TransMembrane:8 (i175-197o241-258i279-297o309-327i560-580o592-613i625- 643o655-678i); go_process: GO:0071765 - nuclear inner membrane organization [Evidence IEA] AKAW2_31034A BUSCO:EOG09263HE6; COG:H; EggNog:ENOG410PKCK; InterPro:IPR004143,IPR004562; PFAM:PF03099; go_process: GO:0006464 - cellular protein modification process [Evidence IEA]; go_process: GO:0009249 - protein lipoylation [Evidence IEA] AKAW2_31035S BUSCO:EOG09262DUV; COG:E; EggNog:ENOG410PGTR; InterPro:IPR020541,IPR000453,IPR035904; PFAM:PF01264; go_function: GO:0004107 - chorismate synthase activity [Evidence IEA]; go_process: GO:0009073 - aromatic amino acid family biosynthetic process [Evidence IEA] AKAW2_31036A COG:S; EggNog:ENOG410PFJY; InterPro:IPR015915,IPR011043; SECRETED:SignalP(1-35); TransMembrane:1 (n19-30c35/36o464-486i); go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_31037S COG:T; EggNog:ENOG410PJZ9; InterPro:IPR000719,IPR011009,IPR008271,IPR017441; PFAM:PF07714; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_31038S CAZy:GH53; COG:G; EggNog:ENOG410PI60; InterPro:IPR017853,IPR011683; PFAM:PF07745; SECRETED:SignalP(1-20); go_function: GO:0015926 - glucosidase activity [Evidence IEA] AKAW2_31039S TransMembrane:1 (o27-51i) AKAW2_31040S COG:K; EggNog:ENOG410PIQA; InterPro:IPR036236,IPR013087; PFAM:PF00096,PF12874,PF13912 AKAW2_31041A BUSCO:EOG09262UB3; CAZy:GT4; COG:M; EggNog:ENOG410PIAX; InterPro:IPR001296,IPR038013,IPR031814; PFAM:PF00534,PF15924,PF13692; go_function: GO:0004377 - GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity [Evidence IEA] AKAW2_31042S COG:U; EggNog:ENOG410PQHW; InterPro:IPR001708; TransMembrane:5 (o51-75i151-170o222-240i260-278o290-312i); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0032977 - membrane insertase activity [Evidence IEA] AKAW2_31043A COG:T; EggNog:ENOG410PFV7; InterPro:IPR036457,IPR001932,IPR015655; PFAM:PF13672,PF00481; TransMembrane:1 (i63-80o); go_function: GO:0004722 - protein serine/threonine phosphatase activity [Evidence IEA]; go_function: GO:0016791 - phosphatase activity [Evidence IEA]; go_process: GO:0006470 - protein dephosphorylation [Evidence IEA] AKAW2_31044S BUSCO:EOG09260TDY; COG:S; EggNog:ENOG410PJK3; InterPro:IPR006994,IPR011990; PFAM:PF04910; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_31045S COG:S; EggNog:ENOG410PJRJ; InterPro:IPR006603; PFAM:PF04193; TransMembrane:8 (o20-42i54-74o80-104i184-201o221-239i259-280o349-367i374- 395o) AKAW2_31046A COG:J; EggNog:ENOG410PRWG; InterPro:IPR038716,IPR027534; PFAM:PF00428; go_component: GO:0005840 - ribosome [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_process: GO:0006414 - translational elongation [Evidence IEA] AKAW2_31047S BUSCO:EOG092629ZN; COG:S; EggNog:ENOG410PFAN; InterPro:IPR018810; PFAM:PF10303 AKAW2_31048S COG:C; EggNog:ENOG410PMY7; InterPro:IPR001670,IPR039697; PFAM:PF00465; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0046872 - metal ion binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_31049A COG:U,Y; EggNog:ENOG410PHA9; InterPro:IPR041653,IPR016024,IPR034085,IPR040122, IPR040928,IPR001494,IPR041389; PFAM:PF18816,PF13513,PF02985,PF18829,PF18808; go_function: GO:0008536 - Ran GTPase binding [Evidence IEA]; go_process: GO:0006606 - protein import into nucleus [Evidence IEA]; go_process: GO:0006886 - intracellular protein transport [Evidence IEA] AKAW2_31050A COG:C; EggNog:ENOG410PG5U; InterPro:IPR000644,IPR000270; PFAM:PF00564,PF00571; TransMembrane:1 (o637-656i); go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_31051S BUSCO:EOG09265GYK; COG:J; EggNog:ENOG410PQ6S; InterPro:IPR038551,IPR000892; PFAM:PF01283; go_component: GO:0005840 - ribosome [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_process: GO:0006412 - translation [Evidence IEA] AKAW2_31052A COG:S; EggNog:ENOG410PKFA AKAW2_31054S COG:S; EggNog:ENOG410Q1Z9 AKAW2_31053A COG:V; EggNog:ENOG410PVIH; InterPro:IPR020464,IPR007822,IPR012341; PFAM:PF05147; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_31055S COG:O; EggNog:ENOG410PGHA; InterPro:IPR002423,IPR012720,IPR027410,IPR027413, IPR017998,IPR002194,IPR027409; PFAM:PF00118; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0051082 - unfolded protein binding [Evidence IEA]; go_process: GO:0006457 - protein folding [Evidence IEA] AKAW2_31056S COG:D,O; EggNog:ENOG410PGJT; InterPro:IPR029030; MEROPS:MER0114503; PFAM:PF00656 AKAW2_31057A BUSCO:EOG092656RK; COG:S; EggNog:ENOG410PI8M; InterPro:IPR007209,IPR022968,IPR007177; PFAM:PF04068,PF04034; go_function: GO:0016740 - transferase activity [Evidence IEA]; go_process: GO:0006364 - rRNA processing [Evidence IEA] AKAW2_31058S BUSCO:EOG09261KZ6; COG:U; EggNog:ENOG410PFC4; InterPro:IPR002014,IPR013041,IPR041198,IPR004152, IPR038425,IPR008152,IPR008153,IPR008942; PFAM:PF03127,PF02883,PF18308,PF00790; go_process: GO:0006886 - intracellular protein transport [Evidence IEA]; go_process: GO:0016192 - vesicle-mediated transport [Evidence IEA] AKAW2_31059S COG:S; EggNog:ENOG410PRUH AKAW2_31060A COG:C; EggNog:ENOG410PITU; InterPro:IPR016711,IPR000644; PFAM:PF00571; go_process: GO:0030071 - regulation of mitotic metaphase/anaphase transition [Evidence IEA]; go_process: GO:0042149 - cellular response to glucose starvation [Evidence IEA] AKAW2_31061A COG:S; EggNog:ENOG410PZR5 AKAW2_31062S COG:D; EggNog:ENOG410PIZ1; InterPro:IPR019236; PFAM:PF09949 AKAW2_31063S COG:C; EggNog:ENOG410PWYZ; InterPro:IPR011032,IPR020843,IPR036291; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA] AKAW2_31064A BUSCO:EOG092631QQ; COG:U; EggNog:ENOG410PJ67; InterPro:IPR008628,IPR038261; PFAM:PF05719; go_function: GO:0070273 - phosphatidylinositol-4-phosphate binding [Evidence IEA] AKAW2_31065A COG:C; EggNog:ENOG410PQGB; InterPro:IPR006162,IPR036736,IPR009081,IPR003231; PFAM:PF00550; go_process: GO:0006633 - fatty acid biosynthetic process [Evidence IEA] AKAW2_31066S COG:C; EggNog:ENOG410PHFE; InterPro:IPR017900,IPR017896,IPR010226; PFAM:PF00037,PF13237,PF13187,PF12838,PF12800; go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0016651 - oxidoreductase activity, acting on NAD(P)H [Evidence IEA]; go_function: GO:0051539 - 4 iron, 4 sulfur cluster binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_31067S COG:S; EggNog:ENOG410PYN8 AKAW2_31068A COG:S; EggNog:ENOG410PJGQ; InterPro:IPR029188,IPR007019,IPR029190; PFAM:PF15459,PF04935 AKAW2_31069A COG:S; EggNog:ENOG410Q1BG; SECRETED:SignalP(1-19) AKAW2_31070S COG:S; EggNog:ENOG410Q1XM; InterPro:IPR008816; PFAM:PF05433; go_component: GO:0019867 - outer membrane [Evidence IEA] AKAW2_31071S BUSCO:EOG09263J7D; COG:J; EggNog:ENOG410PFVK; InterPro:IPR023591,IPR005706,IPR001865; PFAM:PF00318; go_component: GO:0005840 - ribosome [Evidence IEA]; go_component: GO:0015935 - small ribosomal subunit [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_process: GO:0006412 - translation [Evidence IEA] AKAW2_31072A CAZy:GH31; COG:G,M,O; EggNog:ENOG410PHVK; InterPro:IPR025887,IPR000322,IPR017853,IPR011013; PFAM:PF13802,PF01055; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_function: GO:0030246 - carbohydrate binding [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_31073S COG:G; EggNog:ENOG410QEI2; InterPro:IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i65-82o106-129i136-154o166-186i198-217o229-249i298- 321o333-354i361-381o393-412i424-444o456-479i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_31074S COG:S; EggNog:ENOG410PN68; InterPro:IPR036864,IPR001138; PFAM:PF00172; TransMembrane:1 (o511-528i); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_31075A COG:C; EggNog:ENOG410PG0F; InterPro:IPR018108,IPR023395; PFAM:PF00153 AKAW2_31076S BUSCO:EOG09261OIA; COG:J; EggNog:ENOG410PJ0R; InterPro:IPR023115,IPR005225,IPR015760,IPR027417, IPR000795,IPR044145,IPR000178,IPR006847,IPR009000, IPR001876,IPR036925; PFAM:PF00009,PF04760,PF11987,PF01926; go_function: GO:0003743 - translation initiation factor activity [Evidence IEA]; go_function: GO:0003924 - GTPase activity [Evidence IEA]; go_function: GO:0005525 - GTP binding [Evidence IEA]; go_process: GO:0006413 - translational initiation [Evidence IEA] AKAW2_31077A COG:S; EggNog:ENOG410PNW7 AKAW2_31078S COG:S; EggNog:ENOG410PPC4; InterPro:IPR041492,IPR006439,IPR023198,IPR036412, IPR023214; PFAM:PF13242,PF13419; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_31079S COG:S; EggNog:ENOG410PIPK; PFAM:PF07264; TransMembrane:4 (o37-57i69-91o154-177i207-231o) AKAW2_31080S COG:S; EggNog:ENOG410PGBF; InterPro:IPR036864,IPR001138; PFAM:PF00172; TransMembrane:1 (i143-163o); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_31081A SECRETED:SignalP(1-19) AKAW2_31082A COG:T; EggNog:ENOG410PJ6K; InterPro:IPR031329,IPR038445,IPR006823,IPR031331; PFAM:PF17048,PF04734; TransMembrane:1 (i12-33o); go_function: GO:0017040 - N-acylsphingosine amidohydrolase activity [Evidence IEA]; go_process: GO:0046514 - ceramide catabolic process [Evidence IEA] AKAW2_31083S COG:A; EggNog:ENOG410PQ7D; InterPro:IPR008409; PFAM:PF05700; go_process: GO:0006397 - mRNA processing [Evidence IEA] AKAW2_31084S CAZy:AA3; COG:E; EggNog:ENOG410PFAS; InterPro:IPR007867,IPR012132,IPR000172,IPR036188; PFAM:PF00732; go_function: GO:0016614 - oxidoreductase activity, acting on CH-OH group of donors [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_31085A COG:M; EggNog:ENOG410PKKT; InterPro:IPR036291,IPR002225; PFAM:PF07993,PF01073,PF01370; go_function: GO:0003854 - 3-beta-hydroxy-delta5-steroid dehydrogenase activity [Evidence IEA]; go_function: GO:0016616 - oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Evidence IEA]; go_process: GO:0006694 - steroid biosynthetic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_31087S COG:G; EggNog:ENOG410PHC6; InterPro:IPR005829,IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i100-119o131-156i168-187o193-218i230-253o259-284i330- 352o364-388i409-429o435-459i480-498o504-524i); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_31088A COG:S; EggNog:ENOG410PTCV; InterPro:IPR024222; PFAM:PF12658; go_component: GO:1990879 - CST complex [Evidence IEA]; go_function: GO:0043047 - single-stranded telomeric DNA binding [Evidence IEA]; go_process: GO:0016233 - telomere capping [Evidence IEA] AKAW2_31089S BUSCO:EOG09264W71; COG:U; EggNog:ENOG410PJP4; InterPro:IPR005024; PFAM:PF03357; go_process: GO:0007034 - vacuolar transport [Evidence IEA] AKAW2_31090A COG:S; EggNog:ENOG410PGN5; InterPro:IPR013933; PFAM:PF08624 AKAW2_31091S COG:T; EggNog:ENOG410PFAV; InterPro:IPR017441,IPR017892,IPR008271,IPR035892, IPR000961,IPR000008,IPR000719,IPR011009; PFAM:PF00433,PF00168,PF07714,PF14531,PF00069; SECRETED:SignalP(1-16); go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0004674 - protein serine/threonine kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_31092S COG:S; EggNog:ENOG410PGFQ; InterPro:IPR032675 AKAW2_31093S COG:S; EggNog:ENOG410PSSX AKAW2_31095S COG:K; EggNog:ENOG410PF8J; InterPro:IPR000719,IPR011009,IPR008271; PFAM:PF00069; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_31097A TransMembrane:1 (o333-353i) AKAW2_31098A COG:O; EggNog:ENOG410PFP3; InterPro:IPR041569,IPR003959,IPR027417,IPR003593, IPR032501,IPR003960,IPR035254,IPR005937; PFAM:PF16450,PF00004,PF17862; go_component: GO:0005737 - cytoplasm [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016787 - hydrolase activity [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA]; go_function: GO:0036402 - proteasome-activating ATPase activity [Evidence IEA]; go_process: GO:0030163 - protein catabolic process [Evidence IEA] AKAW2_31099A COG:I; EggNog:ENOG410PG43; InterPro:IPR010376,IPR038492,IPR003819,IPR012776, IPR042098; PFAM:PF02668,PF06155; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0050353 - trimethyllysine dioxygenase activity [Evidence IEA]; go_process: GO:0045329 - carnitine biosynthetic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_31100A COG:I; EggNog:ENOG410PI66; InterPro:IPR002539,IPR029069; PFAM:PF01575 AKAW2_31101A COG:K,O,T; EggNog:ENOG410PH9Q; InterPro:IPR029063,IPR041698,IPR025799; PFAM:PF13649,PF08241,PF13847; go_function: GO:0016274 - protein-arginine N-methyltransferase activity [Evidence IEA]; go_process: GO:0018216 - peptidyl-arginine methylation [Evidence IEA] AKAW2_31102S COG:S; EggNog:ENOG410PID0; InterPro:IPR007217; PFAM:PF04080; TransMembrane:7 (o44-62i83-102o114-133i145-167o173-193i205-225o237-255i); go_process: GO:0006506 - GPI anchor biosynthetic process [Evidence IEA] AKAW2_31103S BUSCO:EOG092621YU; COG:G; EggNog:ENOG410PHNA; InterPro:IPR016657,IPR036900,IPR016055,IPR005844, IPR005843,IPR016066; PFAM:PF00408; go_function: GO:0000287 - magnesium ion binding [Evidence IEA]; go_function: GO:0004610 - phosphoacetylglucosamine mutase activity [Evidence IEA]; go_function: GO:0016868 - intramolecular transferase activity, phosphotransferases [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA]; go_process: GO:0071704 - organic substance metabolic process [Evidence IEA] AKAW2_31104A COG:A; EggNog:ENOG410PF8V; InterPro:IPR027417,IPR001650,IPR014014,IPR014001, IPR011545,IPR000629; PFAM:PF04851,PF00270,PF00271; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0004386 - helicase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA] AKAW2_31105S BUSCO:EOG09263NE7; COG:J; EggNog:ENOG410PFZF; InterPro:IPR007109; PFAM:PF04427 AKAW2_31106A COG:H; EggNog:ENOG410PHUK; InterPro:IPR026017,IPR017938,IPR001783,IPR023366; PFAM:PF00677 AKAW2_31107S COG:I; EggNog:ENOG410PGXZ; InterPro:IPR023606,IPR003673; PFAM:PF02515; go_function: GO:0008410 - CoA-transferase activity [Evidence IEA] AKAW2_31108S COG:S; EggNog:ENOG410PQKP; InterPro:IPR019787,IPR019786,IPR011011,IPR001965, IPR013083; PFAM:PF00628 AKAW2_31109A COG:F; EggNog:ENOG410PK4X; InterPro:IPR032466 AKAW2_31110S COG:Q; EggNog:ENOG410PFJE; InterPro:IPR036291,IPR002347; PFAM:PF08659,PF00106,PF13561; TransMembrane:2 (i64-83o103-122i); go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_31111A COG:A; EggNog:ENOG410PGD7; InterPro:IPR036322,IPR007287,IPR015943,IPR001680, IPR020472,IPR017986; PFAM:PF04158,PF00400; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_31112S BUSCO:EOG092630YS; COG:O; EggNog:ENOG410PJ50; InterPro:IPR036390,IPR040773,IPR000717,IPR040780; PFAM:PF18055,PF18503,PF01399 AKAW2_31113S BUSCO:EOG09262IY3; COG:B,K; EggNog:ENOG410PNDZ; InterPro:IPR036885,IPR003121,IPR019835; PFAM:PF02201; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_31114A COG:T; EggNog:ENOG410PHUM; InterPro:IPR006634; PFAM:PF03798; TransMembrane:7 (o35-59i71-94o109-129i136-160o166-187i199-219o279-299i); go_component: GO:0016021 - integral component of membrane [Evidence IEA] AKAW2_31115A COG:S; EggNog:ENOG410PG0R; InterPro:IPR029687,IPR016024; go_process: GO:0043001 - Golgi to plasma membrane protein transport [Evidence IEA] AKAW2_31116S COG:J; EggNog:ENOG410PNDR; InterPro:IPR041991,IPR001141,IPR008991,IPR018262, IPR038655; PFAM:PF01777; go_component: GO:0005840 - ribosome [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_process: GO:0006412 - translation [Evidence IEA] AKAW2_31117S COG:S; EggNog:ENOG410PPWZ; InterPro:IPR037445 AKAW2_31118S InterPro:IPR036770 AKAW2_31119A COG:S; EggNog:ENOG410PZAI AKAW2_31120S COG:G; EggNog:ENOG410PK1T; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i74-92o112-131i143-161o167-189i201-221o233-255i276- 297o309-329i341-360o366-389i401-419o431-450i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_31121S COG:S; EggNog:ENOG410PP33; InterPro:IPR002190,IPR037445,IPR041898,IPR041899; PFAM:PF01454 AKAW2_31122A COG:S; EggNog:ENOG410PQM3; InterPro:IPR002110,IPR020683,IPR036770; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_31123S BUSCO:EOG0926539T; COG:K; EggNog:ENOG410PQ6F; InterPro:IPR001529,IPR012164,IPR001222,IPR034014; PFAM:PF01096,PF02150; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0042779 - tRNA 3'-trailer cleavage [Evidence IEA] AKAW2_31124S COG:J; EggNog:ENOG410PJIR; InterPro:IPR027417,IPR031157,IPR000795,IPR004161, IPR004160,IPR004539,IPR009001,IPR009000; PFAM:PF00009,PF03143,PF03144; go_function: GO:0003746 - translation elongation factor activity [Evidence IEA]; go_function: GO:0003924 - GTPase activity [Evidence IEA]; go_function: GO:0005525 - GTP binding [Evidence IEA]; go_process: GO:0006414 - translational elongation [Evidence IEA] AKAW2_31125A CAZy:GH28; COG:G; EggNog:ENOG410PVTX; InterPro:IPR000743,IPR012334,IPR011050; PFAM:PF00295; SECRETED:SignalP(1-20); go_function: GO:0004650 - polygalacturonase activity [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_31126S BUSCO:EOG09264B74; COG:S; EggNog:ENOG410PMCT; InterPro:IPR016087,IPR036298; PFAM:PF16035; TransMembrane:1 (i73-92o); go_function: GO:0016872 - intramolecular lyase activity [Evidence IEA] AKAW2_31127A COG:O; EggNog:ENOG410PSDM; InterPro:IPR011899,IPR014025,IPR036249,IPR002109; PFAM:PF00462; go_function: GO:0015035 - protein disulfide oxidoreductase activity [Evidence IEA] AKAW2_31128A COG:O; EggNog:ENOG410PSDM AKAW2_31129A COG:S; EggNog:ENOG410PSVN; InterPro:IPR039690,IPR029071,IPR036533,IPR003103; PFAM:PF02179; TransMembrane:1 (n4-13c18/19o68-90i); go_component: GO:0005689 - U12-type spliceosomal complex [Evidence IEA]; go_function: GO:0051087 - chaperone binding [Evidence IEA]; go_process: GO:0000398 - mRNA splicing, via spliceosome [Evidence IEA] AKAW2_31130A COG:S; EggNog:ENOG410PHP6; InterPro:IPR006876; PFAM:PF04791; TransMembrane:9 (o12-30i42-63o91-111i132-149o161-183i349-375o404-425i446- 465o497-515i) AKAW2_31131S COG:S; EggNog:ENOG410PQCP; InterPro:IPR036546,IPR008626; PFAM:PF05397,PF16987; go_component: GO:0016592 - mediator complex [Evidence IEA]; go_function: GO:0003712 - transcription coregulator activity [Evidence IEA]; go_process: GO:0006357 - regulation of transcription by RNA polymerase II [Evidence IEA] AKAW2_31132S COG:G; EggNog:ENOG410PKEW; InterPro:IPR012404,IPR007271; SECRETED:SignalP(1-21); TransMembrane:9 (o6-24i51-74o138-162i169-186o192-216i251-271o291-309i330- 354o374-401i); go_component: GO:0000139 - Golgi membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0015165 - pyrimidine nucleotide-sugar transmembrane transporter activity [Evidence IEA]; go_process: GO:0090481 - pyrimidine nucleotide-sugar transmembrane transport [Evidence IEA] AKAW2_31133A COG:I; EggNog:ENOG410PH83; InterPro:IPR014371,IPR004299; PFAM:PF03062; TransMembrane:9 (i95-115o135-158i170-189o201-220i326-349o369-395i454- 472o478-495i507-529o); go_function: GO:0008374 - O-acyltransferase activity [Evidence IEA] AKAW2_31134A BUSCO:EOG09262X8R; COG:J; EggNog:ENOG410PJDX; InterPro:IPR037171,IPR000649,IPR042529,IPR042528; PFAM:PF01008; go_process: GO:0044237 - cellular metabolic process [Evidence IEA] AKAW2_31135S COG:D; EggNog:ENOG410PIB9; InterPro:IPR005549,IPR041112,IPR038275; PFAM:PF18595,PF03800; go_component: GO:0000776 - kinetochore [Evidence IEA]; go_component: GO:0031262 - Ndc80 complex [Evidence IEA] AKAW2_31136S COG:G; EggNog:ENOG410PJKR; InterPro:IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i62-85o105-127i134-154o160-180i192-211o223-243i267- 288o300-320i332-351o357-376i383-401o421-442i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_31137S BUSCO:EOG09260VHV; COG:U; EggNog:ENOG410PIJZ; InterPro:IPR016024,IPR026739,IPR026740,IPR002553; PFAM:PF01602,PF12717; go_component: GO:0030117 - membrane coat [Evidence IEA]; go_component: GO:0030123 - AP-3 adaptor complex [Evidence IEA]; go_process: GO:0006886 - intracellular protein transport [Evidence IEA]; go_process: GO:0016192 - vesicle-mediated transport [Evidence IEA] AKAW2_31138S COG:G,T; EggNog:ENOG410PHZF; InterPro:IPR004843,IPR029052,IPR006186; PFAM:PF00149; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_31139A BUSCO:EOG09264KK7; COG:T; EggNog:ENOG410PFBP; InterPro:IPR024792,IPR000406,IPR014756; PFAM:PF02115; go_component: GO:0005737 - cytoplasm [Evidence IEA]; go_function: GO:0005094 - Rho GDP-dissociation inhibitor activity [Evidence IEA] AKAW2_31140S COG:S; EggNog:ENOG410PJ33; InterPro:IPR003163,IPR036887,IPR018004,IPR037548; TransMembrane:1 (i416-433o); go_component: GO:1990862 - nuclear membrane complex Bqt3-Bqt4 [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_process: GO:0070197 - meiotic attachment of telomere to nuclear envelope [Evidence IEA] AKAW2_31141S COG:A; EggNog:ENOG410PK9E; InterPro:IPR010655,IPR027417,IPR038238,IPR038239, IPR032319,IPR028606,IPR032324; PFAM:PF06807,PF16575,PF16573; go_component: GO:0005849 - mRNA cleavage factor complex [Evidence IEA]; go_process: GO:0031124 - mRNA 3'-end processing [Evidence IEA] AKAW2_31143S CAZy:CE4; COG:G; EggNog:ENOG410PIQC; InterPro:IPR002509,IPR011330; PFAM:PF01522; TransMembrane:2 (o12-29i41-64o); go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0016810 - hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_31142A COG:S; EggNog:ENOG410PKK7 AKAW2_31145S COG:Q; EggNog:ENOG410PFIW; InterPro:IPR013154,IPR013149,IPR036291,IPR011032, IPR020843,IPR002364; PFAM:PF00107,PF08240,PF13602; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_31146A COG:S; EggNog:ENOG410PQIH; InterPro:IPR018606; PFAM:PF09692; go_component: GO:0033167 - ARC complex [Evidence IEA]; go_process: GO:0031047 - gene silencing by RNA [Evidence IEA] AKAW2_31148S COG:I,K,T; EggNog:ENOG410QDKF; InterPro:IPR005522; PFAM:PF03770; go_function: GO:0016301 - kinase activity [Evidence IEA]; go_process: GO:0032958 - inositol phosphate biosynthetic process [Evidence IEA] AKAW2_31149S COG:J; EggNog:ENOG410PR40; InterPro:IPR002222,IPR020934,IPR023575; PFAM:PF00203; go_component: GO:0005840 - ribosome [Evidence IEA]; go_function: GO:0003723 - RNA binding [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_process: GO:0006412 - translation [Evidence IEA] AKAW2_31150A COG:K; EggNog:ENOG410PNVU; InterPro:IPR003923; PFAM:PF03540; go_component: GO:0005634 - nucleus [Evidence IEA]; go_process: GO:0006352 - DNA-templated transcription, initiation [Evidence IEA] AKAW2_31151A COG:K; EggNog:ENOG410PG9K; InterPro:IPR013867,IPR001005,IPR009057,IPR017930; PFAM:PF08558; go_function: GO:0042162 - telomeric DNA binding [Evidence IEA]; go_function: GO:0042803 - protein homodimerization activity [Evidence IEA] AKAW2_31152S COG:S; EggNog:ENOG410PMWW; InterPro:IPR000560,IPR029033; SECRETED:SignalP(1-22); TransMembrane:1 (n7-17c22/23o458-483i) AKAW2_31153A COG:S; EggNog:ENOG410PNDH; InterPro:IPR011009,IPR002575,IPR008266; PFAM:PF01636; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_31154S COG:G; EggNog:ENOG410PHAQ; InterPro:IPR006598; PFAM:PF05686; SECRETED:SignalP(1-28); TransMembrane:1 (i7-25o) AKAW2_31155S COG:I; EggNog:ENOG410PVA6; InterPro:IPR000073,IPR029058; MEROPS:MER0031617; PFAM:PF12697; TransMembrane:1 (o16-38i) AKAW2_31156S CAZy:GT8; COG:G; EggNog:ENOG410PJHH; InterPro:IPR029044,IPR002495; PFAM:PF01501; go_function: GO:0016757 - transferase activity, transferring glycosyl groups [Evidence IEA] AKAW2_31157A COG:E; EggNog:ENOG410PN84; InterPro:IPR014710,IPR010300,IPR011051; PFAM:PF05995; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016702 - oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_31158S COG:T; EggNog:ENOG410PHWE; InterPro:IPR027417,IPR005225,IPR012675,IPR031662, IPR006074,IPR006073,IPR031167,IPR012676,IPR004095; PFAM:PF02824,PF01926,PF16897; go_function: GO:0005525 - GTP binding [Evidence IEA] AKAW2_31159S COG:S; EggNog:ENOG410PIEJ; InterPro:IPR007889,IPR009057,IPR006600; PFAM:PF03221,PF04218; go_function: GO:0003677 - DNA binding [Evidence IEA] AKAW2_31160A COG:S; EggNog:ENOG410PFU3; InterPro:IPR003114; PFAM:PF02194 AKAW2_31162S COG:F; EggNog:ENOG410PJG7; InterPro:IPR023186,IPR036452,IPR001910; PFAM:PF01156 AKAW2_31163A COG:M; EggNog:ENOG410PGZH; InterPro:IPR029065,IPR034593,IPR023592,IPR036849, IPR013342,IPR013341,IPR029017,IPR018110; PFAM:PF13378,PF02746; go_function: GO:0008869 - galactonate dehydratase activity [Evidence IEA]; go_process: GO:0009063 - cellular amino acid catabolic process [Evidence IEA]; go_process: GO:0034194 - D-galactonate catabolic process [Evidence IEA] AKAW2_31164S COG:U; EggNog:ENOG410PR80; InterPro:IPR018618; PFAM:PF09783; TransMembrane:1 (i43-60o) AKAW2_31165A BUSCO:EOG09265CN0; COG:J; EggNog:ENOG410PN3M; InterPro:IPR000530,IPR004038,IPR029064; PFAM:PF01248; go_component: GO:0005840 - ribosome [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_process: GO:0006412 - translation [Evidence IEA] AKAW2_31166A COG:S; EggNog:ENOG410PM1H; InterPro:IPR002110,IPR020683,IPR036770; PFAM:PF12796,PF00023,PF13857; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_31167S COG:I; EggNog:ENOG410PNBK; InterPro:IPR039698,IPR001104; PFAM:PF02544; TransMembrane:7 (o22-40i96-118o130-148i169-189o209-228i249-271o283-301i); go_function: GO:0003865 - 3-oxo-5-alpha-steroid 4-dehydrogenase activity [Evidence IEA]; go_function: GO:0016627 - oxidoreductase activity, acting on the CH-CH group of donors [Evidence IEA]; go_process: GO:0006488 - dolichol-linked oligosaccharide biosynthetic process [Evidence IEA]; go_process: GO:0006629 - lipid metabolic process [Evidence IEA] AKAW2_31168A COG:S; EggNog:ENOG410PNIY; InterPro:IPR037151,IPR032862 AKAW2_31170A COG:S; EggNog:ENOG410PFQJ; InterPro:IPR011009,IPR002575; PFAM:PF01636 AKAW2_31171S COG:O; EggNog:ENOG410PQBE; InterPro:IPR000297,IPR043323; PFAM:PF13616,PF00639; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0003755 - peptidyl-prolyl cis-trans isomerase activity [Evidence IEA]; go_process: GO:0006364 - rRNA processing [Evidence IEA] AKAW2_31172A BUSCO:EOG09264F1U; COG:G; EggNog:ENOG410PG99; InterPro:IPR013657; PFAM:PF00892,PF08449; TransMembrane:10 (i60-80o106-130i151-169o175-195i202-221o241-261i282- 302o341-359i366-386o392-411i); go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_31173S COG:S; EggNog:ENOG410PXEM; InterPro:IPR018593,IPR036167,IPR042777; PFAM:PF09631; go_component: GO:0000214 - tRNA-intron endonuclease complex [Evidence IEA]; go_process: GO:0000379 - tRNA-type intron splice site recognition and cleavage [Evidence IEA]; go_process: GO:0006388 - tRNA splicing, via endonucleolytic cleavage and ligation [Evidence IEA] AKAW2_31174A COG:T; EggNog:ENOG410PHZZ; InterPro:IPR039463,IPR031968,IPR027267,IPR011993, IPR001849,IPR042067; PFAM:PF16016,PF00169; TransMembrane:2 (o1149-1167i1179-1196o) AKAW2_31175S BUSCO:EOG09262POL; COG:J; EggNog:ENOG410PME2; InterPro:IPR018034,IPR024626; PFAM:PF05178,PF12936 AKAW2_31176S COG:C; EggNog:ENOG410PG5Y; InterPro:IPR018108,IPR002067,IPR023395,IPR002113; PFAM:PF00153; TransMembrane:2 (i185-204o224-245i); go_component: GO:0005743 - mitochondrial inner membrane [Evidence IEA]; go_function: GO:0005471 - ATP:ADP antiporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA]; go_process: GO:0140021 - mitochondrial ADP transmembrane transport [Evidence IEA]; go_process: GO:1990544 - mitochondrial ATP transmembrane transport [Evidence IEA] AKAW2_31177S COG:S; EggNog:ENOG410Q1MT AKAW2_31178A COG:S; EggNog:ENOG410PK59; InterPro:IPR018818; PFAM:PF10330 AKAW2_31179S COG:I; EggNog:ENOG410PFKD; InterPro:IPR023606,IPR003673; PFAM:PF02515; go_function: GO:0008410 - CoA-transferase activity [Evidence IEA] AKAW2_31180S COG:S; EggNog:ENOG410PQQ8; InterPro:IPR032710 AKAW2_31181A COG:V; EggNog:ENOG410PI32; InterPro:IPR020422,IPR000073,IPR029021,IPR029058, IPR016130,IPR000387,IPR000340; PFAM:PF12146,PF00561,PF00782,PF12697; TransMembrane:1 (o62-82i); go_function: GO:0004725 - protein tyrosine phosphatase activity [Evidence IEA]; go_function: GO:0008138 - protein tyrosine/serine/threonine phosphatase activity [Evidence IEA]; go_function: GO:0016791 - phosphatase activity [Evidence IEA]; go_process: GO:0006470 - protein dephosphorylation [Evidence IEA]; go_process: GO:0016311 - dephosphorylation [Evidence IEA] AKAW2_31182A COG:E; EggNog:ENOG410PKQ6; InterPro:IPR000581,IPR004404,IPR037237,IPR042096, IPR020558; PFAM:PF00920; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0004160 - dihydroxy-acid dehydratase activity [Evidence IEA]; go_process: GO:0009082 - branched-chain amino acid biosynthetic process [Evidence IEA] AKAW2_31183A COG:O; EggNog:ENOG410PH42; InterPro:IPR006845; PFAM:PF04757; TransMembrane:2 (i205-223o259-280i) AKAW2_31184S COG:S; EggNog:ENOG410PH8E; InterPro:IPR007312; PFAM:PF04185; SECRETED:SignalP(1-17); TransMembrane:1 (n4-12c17/18o425-447i); go_function: GO:0016788 - hydrolase activity, acting on ester bonds [Evidence IEA] AKAW2_31185A COG:C; EggNog:ENOG410PUP5; InterPro:IPR015590,IPR016161,IPR016162,IPR016163; PFAM:PF00171; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0016620 - oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_31186A COG:S; EggNog:ENOG410PU0Y AKAW2_31187S BUSCO:EOG09260DUW; COG:U,Y; EggNog:ENOG410PHZE; InterPro:IPR001494,IPR016024,IPR011989; PFAM:PF03810; go_function: GO:0008536 - Ran GTPase binding [Evidence IEA]; go_process: GO:0006886 - intracellular protein transport [Evidence IEA] AKAW2_31188A CAZy:GH5; COG:G; EggNog:ENOG410PJVJ; InterPro:IPR017853,IPR001547; PFAM:PF00150; SECRETED:SignalP(1-22); go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_process: GO:0071704 - organic substance metabolic process [Evidence IEA] AKAW2_31189S COG:S; EggNog:ENOG410PIKX; InterPro:IPR012292; PFAM:PF11563; go_function: GO:0019825 - oxygen binding [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA] AKAW2_31190S COG:C; EggNog:ENOG410PICX; InterPro:IPR015590,IPR016161,IPR016162,IPR016163; PFAM:PF00171; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0016620 - oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_31191S COG:S; EggNog:ENOG410Q2ST; InterPro:IPR018466; PFAM:PF10342; SECRETED:SignalP(1-18) AKAW2_31192S COG:S; EggNog:ENOG410PU3T; InterPro:IPR019034; PFAM:PF09495 AKAW2_31193A COG:S; EggNog:ENOG410PK81; InterPro:IPR001138; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_31194S COG:O; EggNog:ENOG410PU75; InterPro:IPR002828,IPR036523; PFAM:PF01975; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_31195A BUSCO:EOG09264NDD; COG:S; EggNog:ENOG410PHBU; InterPro:IPR018814; PFAM:PF10310 AKAW2_31196S COG:S; EggNog:ENOG410PZJI AKAW2_31197S COG:S; EggNog:ENOG410PKIC; InterPro:IPR036236,IPR013087,IPR003656; go_function: GO:0003677 - DNA binding [Evidence IEA] AKAW2_31198A COG:S; EggNog:ENOG410PS91; InterPro:IPR005349; PFAM:PF03647; TransMembrane:3 (n9-16c20/21o30-49i61-78o84-104i); go_component: GO:0016020 - membrane [Evidence IEA] AKAW2_31199A COG:G; EggNog:ENOG410PFNS; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:10 (o12-34i46-63o75-95i107-128o148-170i246-269o301-321i333- 353o359-383i429-449o); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_31200A COG:O,P; EggNog:ENOG410PI09; InterPro:IPR036757,IPR007365,IPR034308,IPR003137, IPR039373,IPR007484; MEROPS:MER0015691; PFAM:PF04253,PF02225,PF04389; TransMembrane:1 (i45-67o) AKAW2_31201A COG:S; EggNog:ENOG410PQHZ; InterPro:IPR028094,IPR039024; PFAM:PF14474 AKAW2_31202A BUSCO:EOG0926146A; COG:S; EggNog:ENOG410PH0F; InterPro:IPR007941,IPR029058; PFAM:PF05277; TransMembrane:3 (o511-529i591-622o634-658i) AKAW2_31204A COG:S; EggNog:ENOG410PVHI; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; TransMembrane:4 (o230-249i270-287o293-313i530-548o); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_31205S COG:S; EggNog:ENOG410PMYI; InterPro:IPR009644,IPR007074; SECRETED:SignalP(1-24) AKAW2_31206S COG:K; EggNog:ENOG410PHTN; InterPro:IPR007219; PFAM:PF04082; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA] AKAW2_31207S BUSCO:EOG09265JA7; COG:O; EggNog:ENOG410PQXP; InterPro:IPR003038; PFAM:PF02109; TransMembrane:3 (i75-99o105-123i171-189o); go_component: GO:0008250 - oligosaccharyltransferase complex [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA] AKAW2_31208A COG:A; EggNog:ENOG410PHRD; InterPro:IPR011709,IPR027417,IPR001650,IPR014001, IPR007502,IPR011545,IPR002464; PFAM:PF04408,PF00270,PF07717,PF00271; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0004386 - helicase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA] AKAW2_31209S BUSCO:EOG09265BAK; COG:O; EggNog:ENOG410PPNG; InterPro:IPR002777,IPR027235,IPR009053; PFAM:PF01920; go_component: GO:0016272 - prefoldin complex [Evidence IEA]; go_function: GO:0051082 - unfolded protein binding [Evidence IEA]; go_process: GO:0006457 - protein folding [Evidence IEA] AKAW2_31210S InterPro:IPR036864,IPR001138; PFAM:PF00172; TransMembrane:1 (o549-570i); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_31211S COG:S; EggNog:ENOG410Q2PM; InterPro:IPR000073,IPR029058; PFAM:PF12697 AKAW2_31212A COG:O; EggNog:ENOG410PQ2A; InterPro:IPR001623,IPR036869,IPR018253; PFAM:PF00226 AKAW2_31213A COG:S; EggNog:ENOG410PGFV; InterPro:IPR004843,IPR029052; PFAM:PF00149; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_31214S BUSCO:EOG09260Z3X; COG:O; EggNog:ENOG410PG3U; InterPro:IPR004839,IPR015424,IPR015421,IPR015422; PFAM:PF00155; TransMembrane:1 (i89-108o); go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0030170 - pyridoxal phosphate binding [Evidence IEA]; go_process: GO:0009058 - biosynthetic process [Evidence IEA] AKAW2_31215S COG:J; EggNog:ENOG410PHKH; InterPro:IPR005755,IPR005822,IPR023563,IPR036899; PFAM:PF00572; go_component: GO:0005840 - ribosome [Evidence IEA]; go_component: GO:0015934 - large ribosomal subunit [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_process: GO:0006412 - translation [Evidence IEA] AKAW2_31216S COG:I; EggNog:ENOG410PIY6; InterPro:IPR000873,IPR020845,IPR042099,IPR025110; PFAM:PF00501,PF13193 AKAW2_31217S BUSCO:EOG09260GOF; COG:S; EggNog:ENOG410QEH4; InterPro:IPR001810,IPR006553,IPR036047,IPR032675; PFAM:PF00646,PF12937; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_31218S COG:O; EggNog:ENOG410PIZ5; InterPro:IPR007484; MEROPS:MER0001911; PFAM:PF04389; TransMembrane:9 (i12-36o393-415i448-467o479-499i511-531o537-558i666- 694o706-727i734-755o) AKAW2_31219A BUSCO:EOG092602I6; COG:K; EggNog:ENOG410PIIR; InterPro:IPR016024,IPR011989,IPR027417,IPR022707, IPR000330,IPR038718,IPR001650,IPR044078,IPR014001; PFAM:PF00176,PF12054,PF00271; go_function: GO:0005524 - ATP binding [Evidence IEA] AKAW2_31220A COG:C; EggNog:ENOG410PQWP AKAW2_31221S COG:U; EggNog:ENOG410PM9V; InterPro:IPR013244; PFAM:PF08314; SECRETED:SignalP(1-27); go_process: GO:0006890 - retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [Evidence IEA] AKAW2_31222A TransMembrane:5 (o25-46i58-76o82-100i112-133o139-156i) AKAW2_31223A COG:T; EggNog:ENOG410PGDC; InterPro:IPR017441,IPR008271,IPR000719,IPR011009; PFAM:PF07714,PF00069; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_31224S COG:S; EggNog:ENOG410PXNI; SECRETED:SignalP(1-17) AKAW2_31226S COG:S; EggNog:ENOG410Q285; InterPro:IPR022812,IPR027417; PFAM:PF00350,PF01926 AKAW2_31227S COG:O; EggNog:ENOG410PHAJ; InterPro:IPR011990,IPR001623,IPR036869,IPR019734, IPR013026,IPR018253,IPR001440; PFAM:PF07719,PF00515,PF00226,PF13181,PF13414, PF12895,PF13432,PF13174,PF14559; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_31228A COG:S; EggNog:ENOG410PNGJ; TransMembrane:4 (i25-48o78-99i111-135o155-174i) AKAW2_31229A COG:S; EggNog:ENOG410PVRC; TransMembrane:2 (o61-82i94-113o) AKAW2_31230S COG:T; EggNog:ENOG410PHC9; InterPro:IPR000719,IPR011009,IPR008271; PFAM:PF07714,PF00069; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_31231S BUSCO:EOG09264V30; COG:K; EggNog:ENOG410PNX9; InterPro:IPR019145; PFAM:PF09748; go_component: GO:0016592 - mediator complex [Evidence IEA]; go_function: GO:0003712 - transcription coregulator activity [Evidence IEA]; go_process: GO:0006357 - regulation of transcription by RNA polymerase II [Evidence IEA] AKAW2_31232S COG:S; EggNog:ENOG410PHZM; TransMembrane:7 (o26-50i57-81o87-109i121-145o165-184i205-225o237-257i) AKAW2_31233A COG:S; EggNog:ENOG410PPIV; InterPro:IPR010730; PFAM:PF06985 AKAW2_31234A COG:S; EggNog:ENOG410PKX7; InterPro:IPR009306; PFAM:PF06131 AKAW2_31235A COG:S; EggNog:ENOG410PKEC; InterPro:IPR014622,IPR007815; PFAM:PF05139; go_process: GO:0046677 - response to antibiotic [Evidence IEA] AKAW2_31236S COG:S; EggNog:ENOG410PJIJ AKAW2_31237A COG:I; EggNog:ENOG410PN56; InterPro:IPR019388; PFAM:PF10261; TransMembrane:6 (i21-41o96-116i128-146o200-219i256-276o282-298i); go_component: GO:0005789 - endoplasmic reticulum membrane [Evidence IEA]; go_process: GO:0019915 - lipid storage [Evidence IEA] AKAW2_31238A CAZy:GH3; COG:G; EggNog:ENOG410PG84; InterPro:IPR017853,IPR019800,IPR036962,IPR002772, IPR036881,IPR026891,IPR013783,IPR001764; PFAM:PF14310,PF00933,PF01915; SECRETED:SignalP(1-19); go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_31239S COG:P; EggNog:ENOG410PIA4; InterPro:IPR004706; TransMembrane:1 (o40-59i); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0015103 - inorganic anion transmembrane transporter activity [Evidence IEA]; go_function: GO:0015297 - antiporter activity [Evidence IEA] AKAW2_31240S COG:P; EggNog:ENOG410PIA4; InterPro:IPR002657,IPR038770,IPR004706; TransMembrane:5 (n2-12c17/18o33-55i67-86o98-119i131-154o160-181i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0015103 - inorganic anion transmembrane transporter activity [Evidence IEA]; go_function: GO:0015297 - antiporter activity [Evidence IEA] AKAW2_31241A COG:S; EggNog:ENOG410Q2P1 AKAW2_31242S COG:K; EggNog:ENOG410PFRU; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_31243A COG:U; EggNog:ENOG410PKV8; InterPro:IPR009011,IPR028927; PFAM:PF02157,PF09451; SECRETED:SignalP(1-23); TransMembrane:2 (n8-19c23/24o212-231i252-274o) AKAW2_31244S COG:I; EggNog:ENOG410PFWY; InterPro:IPR001171,IPR018083; PFAM:PF01222; TransMembrane:8 (i21-42o89-107i127-148o160-181i266-285o305-323i335- 354o445-464i); go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0016628 - oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor [Evidence IEA]; go_process: GO:0016126 - sterol biosynthetic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_31245A BUSCO:EOG09263CG2; COG:A; EggNog:ENOG410PICF; InterPro:IPR002466,IPR042935; PFAM:PF02137; go_function: GO:0003723 - RNA binding [Evidence IEA]; go_function: GO:0004000 - adenosine deaminase activity [Evidence IEA]; go_function: GO:0008251 - tRNA-specific adenosine deaminase activity [Evidence IEA]; go_process: GO:0002100 - tRNA wobble adenosine to inosine editing [Evidence IEA]; go_process: GO:0006396 - RNA processing [Evidence IEA] AKAW2_31246S COG:A; EggNog:ENOG410PR7A; InterPro:IPR017089,IPR009846; PFAM:PF07189; go_process: GO:0000398 - mRNA splicing, via spliceosome [Evidence IEA] AKAW2_31247A COG:S; EggNog:ENOG410PJHN; InterPro:IPR024500,IPR023393; PFAM:PF11274 AKAW2_31248A COG:S; EggNog:ENOG410PIVG AKAW2_31250A COG:O; EggNog:ENOG410PQT5; InterPro:IPR017937,IPR005746,IPR036249,IPR013766; PFAM:PF00085,PF00578,PF13098; go_function: GO:0015035 - protein disulfide oxidoreductase activity [Evidence IEA]; go_process: GO:0006662 - glycerol ether metabolic process [Evidence IEA]; go_process: GO:0045454 - cell redox homeostasis [Evidence IEA] AKAW2_31251S COG:S; EggNog:ENOG410PZ2E; SECRETED:SignalP(1-19) AKAW2_31252A COG:S; EggNog:ENOG410PYTX AKAW2_31253S COG:S; EggNog:ENOG410PMAJ; InterPro:IPR039931,IPR019448; PFAM:PF10358 AKAW2_31254S COG:S; EggNog:ENOG410Q0UQ; InterPro:IPR032741; PFAM:PF14611; go_component: GO:0005743 - mitochondrial inner membrane [Evidence IEA] AKAW2_31255A CAZy:GH5; COG:I; EggNog:ENOG410PFKX; InterPro:IPR017853 AKAW2_31256S BUSCO:EOG09261ABB; COG:I,U; EggNog:ENOG410PH67; InterPro:IPR029021,IPR010569,IPR011993,IPR016130, IPR030564; PFAM:PF06602; go_function: GO:0004725 - protein tyrosine phosphatase activity [Evidence IEA]; go_process: GO:0016311 - dephosphorylation [Evidence IEA] AKAW2_31257S BUSCO:EOG092647L7; COG:J; EggNog:ENOG410PGWV; InterPro:IPR001351,IPR009019,IPR036419,IPR015946, IPR005703,IPR018280,IPR004044; PFAM:PF00189,PF07650; go_component: GO:0015935 - small ribosomal subunit [Evidence IEA]; go_function: GO:0003723 - RNA binding [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_process: GO:0006412 - translation [Evidence IEA] AKAW2_31258A BUSCO:EOG09260VTA; COG:J; EggNog:ENOG410PGUM; InterPro:IPR009061,IPR020825,IPR005146,IPR005147, IPR041616,IPR004531,IPR040659; PFAM:PF03483,PF18262,PF03484,PF17759; go_component: GO:0005737 - cytoplasm [Evidence IEA]; go_function: GO:0000166 - nucleotide binding [Evidence IEA]; go_function: GO:0000287 - magnesium ion binding [Evidence IEA]; go_function: GO:0003723 - RNA binding [Evidence IEA]; go_function: GO:0004826 - phenylalanine-tRNA ligase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006432 - phenylalanyl-tRNA aminoacylation [Evidence IEA] AKAW2_31259S BUSCO:EOG09261AH9; COG:T; EggNog:ENOG410PFRF; InterPro:IPR016024,IPR011989,IPR021133; PFAM:PF13646 AKAW2_31260S COG:S; EggNog:ENOG410PXJ6; InterPro:IPR013130; PFAM:PF01794; TransMembrane:7 (o29-45i88-107o127-152i164-186o206-225i246-266o272-290i) AKAW2_31261S COG:S; EggNog:ENOG410PYNM AKAW2_31262S COG:T; EggNog:ENOG410PGX9; InterPro:IPR000719,IPR011009,IPR008271; PFAM:PF07714,PF00069; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_31263S BUSCO:EOG09265RGI; COG:S; EggNog:ENOG410PS2N; InterPro:IPR013965; PFAM:PF08656; go_component: GO:0042729 - DASH complex [Evidence IEA]; go_component: GO:0072686 - mitotic spindle [Evidence IEA]; go_process: GO:0008608 - attachment of spindle microtubules to kinetochore [Evidence IEA] AKAW2_31264A BUSCO:EOG092634G9; COG:J; EggNog:ENOG410PJY2; InterPro:IPR005324,IPR013810,IPR000851,IPR020568, IPR014721; PFAM:PF03719,PF00333; go_component: GO:0005840 - ribosome [Evidence IEA]; go_function: GO:0003723 - RNA binding [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_process: GO:0006412 - translation [Evidence IEA] AKAW2_31265S COG:J; EggNog:ENOG410PGD0; InterPro:IPR012340,IPR029063,IPR030391,IPR030390, IPR010280,IPR025795; go_function: GO:0008173 - RNA methyltransferase activity [Evidence IEA]; go_function: GO:0030697 - S-adenosylmethionine-dependent tRNA (m5U54) methyltransferase activity [Evidence IEA]; go_process: GO:0006396 - RNA processing [Evidence IEA]; go_process: GO:0008033 - tRNA processing [Evidence IEA] AKAW2_31266A COG:C; EggNog:ENOG410PGVS; InterPro:IPR041694,IPR013149,IPR036291,IPR011032; PFAM:PF00107,PF13602,PF16884; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_31267A COG:Z; EggNog:ENOG410PGM8; InterPro:IPR020902,IPR004000,IPR015623,IPR043129; PFAM:PF00022; go_component: GO:0005885 - Arp2/3 protein complex [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0007015 - actin filament organization [Evidence IEA]; go_process: GO:0034314 - Arp2/3 complex-mediated actin nucleation [Evidence IEA] AKAW2_31268S COG:E; EggNog:ENOG410PHRR; InterPro:IPR000246,IPR029055,IPR037464; MEROPS:MER0016969; PFAM:PF01112; go_function: GO:0004298 - threonine-type endopeptidase activity [Evidence IEA]; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_31269A BUSCO:EOG0926369X; COG:K; EggNog:ENOG410PIUI; InterPro:IPR036465,IPR004600; PFAM:PF03850; go_component: GO:0000439 - transcription factor TFIIH core complex [Evidence IEA]; go_process: GO:0006289 - nucleotide-excision repair [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_31270A COG:U; EggNog:ENOG410PGMV; InterPro:IPR033506,IPR017946,IPR002110,IPR030395, IPR036770,IPR020683,IPR004331; PFAM:PF12796,PF00023,PF03009,PF13637; go_function: GO:0005515 - protein binding [Evidence IEA]; go_function: GO:0008081 - phosphoric diester hydrolase activity [Evidence IEA]; go_function: GO:0047389 - glycerophosphocholine phosphodiesterase activity [Evidence IEA]; go_process: GO:0006629 - lipid metabolic process [Evidence IEA]; go_process: GO:0046475 - glycerophospholipid catabolic process [Evidence IEA] AKAW2_31271A BUSCO:EOG09261W1K; COG:D,O; EggNog:ENOG410PIQT; InterPro:IPR016024,IPR024660,IPR011989; PFAM:PF11701 AKAW2_31272A BUSCO:EOG09260SAH; COG:D; EggNog:ENOG410PFAA; InterPro:IPR007857,IPR035075,IPR029063,IPR025799, IPR035247,IPR035248; PFAM:PF17286,PF05185,PF17285; go_function: GO:0008168 - methyltransferase activity [Evidence IEA]; go_function: GO:0016274 - protein-arginine N-methyltransferase activity [Evidence IEA]; go_process: GO:0006479 - protein methylation [Evidence IEA]; go_process: GO:0018216 - peptidyl-arginine methylation [Evidence IEA]; go_process: GO:0035246 - peptidyl-arginine N-methylation [Evidence IEA] AKAW2_31273S COG:A; EggNog:ENOG410PGYC; InterPro:IPR011709,IPR027417,IPR001650,IPR014001, IPR007502,IPR011545,IPR002464; PFAM:PF04408,PF00270,PF07717,PF00271; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0004386 - helicase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA] AKAW2_31274A COG:S; EggNog:ENOG410PQH2 AKAW2_31275S COG:S; EggNog:ENOG410PNVN; InterPro:IPR040250,IPR002048,IPR011992; SECRETED:SignalP(1-21); go_function: GO:0005509 - calcium ion binding [Evidence IEA] AKAW2_31276A COG:J; EggNog:ENOG410PN2X; InterPro:IPR030382,IPR026274,IPR029063; go_function: GO:0008757 - S-adenosylmethionine-dependent methyltransferase activity [Evidence IEA]; go_process: GO:0031591 - wybutosine biosynthetic process [Evidence IEA] AKAW2_31277A COG:C; EggNog:ENOG410PGWT; InterPro:IPR016166,IPR006094,IPR036318; PFAM:PF01565; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_function: GO:0071949 - FAD binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_31278A COG:U; EggNog:ENOG410PH4R; InterPro:IPR015943,IPR001680,IPR036322; TransMembrane:1 (o42-60i); go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_31279S COG:J; EggNog:ENOG410PH6S; InterPro:IPR041667,IPR029063,IPR003347,IPR015915, IPR007213; PFAM:PF13418,PF04072,PF13854; go_function: GO:0005515 - protein binding [Evidence IEA]; go_function: GO:0008168 - methyltransferase activity [Evidence IEA]; go_process: GO:0032259 - methylation [Evidence IEA] AKAW2_31280S COG:V; EggNog:ENOG410PIGU; InterPro:IPR029021,IPR003595,IPR020422,IPR016130, IPR000387,IPR000340; go_function: GO:0004725 - protein tyrosine phosphatase activity [Evidence IEA]; go_function: GO:0008138 - protein tyrosine/serine/threonine phosphatase activity [Evidence IEA]; go_function: GO:0016791 - phosphatase activity [Evidence IEA]; go_process: GO:0006470 - protein dephosphorylation [Evidence IEA]; go_process: GO:0016311 - dephosphorylation [Evidence IEA] AKAW2_31281A BUSCO:EOG092615IE; COG:L; EggNog:ENOG410PH9T; InterPro:IPR002099,IPR014762,IPR036890,IPR038973, IPR013507,IPR020568,IPR032189,IPR014721; PFAM:PF13589,PF16413,PF01119,PF02518; go_component: GO:0032300 - mismatch repair complex [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA]; go_function: GO:0030983 - mismatched DNA binding [Evidence IEA]; go_process: GO:0006298 - mismatch repair [Evidence IEA] AKAW2_31282S COG:S; EggNog:ENOG410PI7Y; TransMembrane:1 (i41-58o) AKAW2_31283S BUSCO:EOG09260JED; COG:O; EggNog:ENOG410PFH6; InterPro:IPR002015,IPR016024,IPR011989,IPR016643, IPR040892,IPR041433; PFAM:PF01851,PF17781,PF18051; TransMembrane:2 (o781-798i810-827o); go_component: GO:0000502 - proteasome complex [Evidence IEA]; go_function: GO:0030234 - enzyme regulator activity [Evidence IEA]; go_process: GO:0042176 - regulation of protein catabolic process [Evidence IEA] AKAW2_31284S BUSCO:EOG09262KVB; COG:T; EggNog:ENOG410PFZS; InterPro:IPR000687,IPR036388,IPR018935,IPR036390, IPR015285,IPR030484,IPR011009; PFAM:PF01163,PF09202; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0004674 - protein serine/threonine kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_31285S BUSCO:EOG09264HX6; COG:J; EggNog:ENOG410PRXZ; InterPro:IPR012677,IPR012678,IPR013025; PFAM:PF00276; go_component: GO:0005840 - ribosome [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_process: GO:0006412 - translation [Evidence IEA] AKAW2_31286A COG:O; EggNog:ENOG410PJ7K; InterPro:IPR027417,IPR027065,IPR003959,IPR008269, IPR027501,IPR003593,IPR004815,IPR015947,IPR020568, IPR003111,IPR014721; MEROPS:MER0000485; PFAM:PF00004,PF13541,PF05362,PF07726,PF07728, PF02190; go_function: GO:0004176 - ATP-dependent peptidase activity [Evidence IEA]; go_function: GO:0004252 - serine-type endopeptidase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA]; go_process: GO:0006508 - proteolysis [Evidence IEA]; go_process: GO:0006515 - protein quality control for misfolded or incompletely synthesized proteins [Evidence IEA]; go_process: GO:0030163 - protein catabolic process [Evidence IEA] AKAW2_31287S BUSCO:EOG09262YP5; COG:H; EggNog:ENOG410PHQP; InterPro:IPR000860,IPR036803,IPR022419,IPR022418, IPR022417; PFAM:PF03900,PF01379; go_function: GO:0004418 - hydroxymethylbilane synthase activity [Evidence IEA]; go_process: GO:0018160 - peptidyl-pyrromethane cofactor linkage [Evidence IEA]; go_process: GO:0033014 - tetrapyrrole biosynthetic process [Evidence IEA] AKAW2_31288A BUSCO:EOG092648LP; COG:T; EggNog:ENOG410PHEG; InterPro:IPR038511,IPR007304; PFAM:PF04177; go_process: GO:0009966 - regulation of signal transduction [Evidence IEA] AKAW2_31289S COG:A; EggNog:ENOG410PGGB; InterPro:IPR027417,IPR038248,IPR005034,IPR036389, IPR000999,IPR001650,IPR014001,IPR006935; PFAM:PF03368,PF00270,PF00271,PF04851,PF00636, PF14622; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0004525 - ribonuclease III activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016787 - hydrolase activity [Evidence IEA]; go_function: GO:0016891 - endoribonuclease activity, producing 5'-phosphomonoesters [Evidence IEA]; go_process: GO:0006396 - RNA processing [Evidence IEA] AKAW2_31290S COG:Z; EggNog:ENOG410PGYZ; InterPro:IPR024743,IPR041658,IPR003593,IPR041466, IPR043157,IPR013594,IPR042228,IPR024317,IPR027417, IPR013602,IPR035706,IPR042219,IPR035699,IPR004273, IPR042222; PFAM:PF12775,PF12774,PF07728,PF08385,PF12777, PF03028,PF17852,PF12780,PF12781,PF08393,PF00004,PF18198; TransMembrane:1 (o3503-3522i); go_component: GO:0030286 - dynein complex [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0008569 - ATP-dependent microtubule motor activity, minus-end-directed [Evidence IEA]; go_process: GO:0007018 - microtubule-based movement [Evidence IEA] AKAW2_31291A COG:B; EggNog:ENOG410PZC7; InterPro:IPR001951,IPR009072; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0046982 - protein heterodimerization activity [Evidence IEA] AKAW2_31292A COG:A; EggNog:ENOG410PFCQ; InterPro:IPR013931,IPR033394; PFAM:PF08622,PF17187; go_process: GO:0006979 - response to oxidative stress [Evidence IEA] AKAW2_31293S BUSCO:EOG09265BG5; COG:J; EggNog:ENOG410PNVD; InterPro:IPR006519,IPR036769,IPR020784,IPR000911, IPR020783,IPR036796; PFAM:PF00298,PF03946; go_component: GO:0005840 - ribosome [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_process: GO:0006412 - translation [Evidence IEA] AKAW2_31294S COG:T; EggNog:ENOG410PGRB; InterPro:IPR017441,IPR008271,IPR000719,IPR011009; PFAM:PF07714,PF00069; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_31295S BUSCO:EOG09263EDC; COG:C; EggNog:ENOG410PJUF; InterPro:IPR018108,IPR023395; PFAM:PF00153 AKAW2_31296A COG:S; EggNog:ENOG410PP5T; InterPro:IPR014710,IPR011051,IPR009327,IPR039935; PFAM:PF06172 AKAW2_31297S COG:G; EggNog:ENOG410PGH2; InterPro:IPR036322,IPR019775,IPR015943,IPR001680, IPR021772,IPR020472,IPR017986; PFAM:PF11816; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_31298A COG:S; EggNog:ENOG410PURU; InterPro:IPR036291,IPR008030; PFAM:PF13460,PF05368,PF01370 AKAW2_31299S COG:S; EggNog:ENOG410PYIG; InterPro:IPR025213; PFAM:PF13095 AKAW2_31300A COG:S; EggNog:ENOG410PXUZ AKAW2_31301S COG:S; EggNog:ENOG410PYN0; TransMembrane:1 (o404-425i) AKAW2_31303S COG:Q; EggNog:ENOG410PHDJ; InterPro:IPR036291,IPR002347; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_31302A COG:S; EggNog:ENOG410Q29U; InterPro:IPR036864,IPR001138; PFAM:PF00172; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_31304S COG:E; EggNog:ENOG410PIB1; InterPro:IPR043137,IPR029055,IPR043138; MEROPS:MER0094876; PFAM:PF01019 AKAW2_31305A COG:Q; EggNog:ENOG410PHXR; InterPro:IPR013149,IPR011032,IPR036291; PFAM:PF00107; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_31306A COG:E; EggNog:ENOG410PUTJ; InterPro:IPR036052,IPR000634,IPR001926; PFAM:PF00291; go_function: GO:0030170 - pyridoxal phosphate binding [Evidence IEA]; go_process: GO:0006520 - cellular amino acid metabolic process [Evidence IEA] AKAW2_31307A COG:S; EggNog:ENOG410PSKI; InterPro:IPR000073,IPR029058; PFAM:PF12697; antiSMASH:Cluster_3.6 AKAW2_31308S COG:S; EggNog:ENOG410PISV; InterPro:IPR001279,IPR036866; antiSMASH:Cluster_3.6 AKAW2_31310S COG:S; EggNog:ENOG410PKJ9; InterPro:IPR024975; PFAM:PF13020; antiSMASH:Cluster_3.6 AKAW2_31309A COG:Q; EggNog:ENOG410PNM8; InterPro:IPR001128,IPR017972,IPR002401,IPR036396; PFAM:PF00067; SMCOG1034:cytochrome P450; TransMembrane:2 (o6-31i38-55o); antiSMASH:Cluster_3.6; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_31311A COG:O; EggNog:ENOG410PGF2; InterPro:IPR036249,IPR040079,IPR036282,IPR010987, IPR004045,IPR004046; PFAM:PF13409,PF00043,PF14497,PF13417,PF02798; SMCOG1193:glutathione S-transferase; antiSMASH:Cluster_3.6; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0006749 - glutathione metabolic process [Evidence IEA] AKAW2_31312S COG:Q; EggNog:ENOG410PIWX; InterPro:IPR001128,IPR002403,IPR017972,IPR036396; PFAM:PF00067; SMCOG1034:cytochrome P450; antiSMASH:Cluster_3.6; go_function: GO:0004497 - monooxygenase activity [Evidence IEA]; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_31313A COG:I; EggNog:ENOG410PIJA; InterPro:IPR016036,IPR016035,IPR001227,IPR014043, IPR018201,IPR016039,IPR032821,IPR014030,IPR014031, IPR020841; PFAM:PF16197,PF00109,PF02801,PF00698; SMCOG1093:Beta-ketoacyl synthase; antiSMASH:Cluster_3.6; go_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein] synthase activity [Evidence IEA]; go_function: GO:0016740 - transferase activity [Evidence IEA]; go_function: GO:0016746 - transferase activity, transferring acyl groups [Evidence IEA]; go_process: GO:0006633 - fatty acid biosynthetic process [Evidence IEA] AKAW2_31314S COG:C; EggNog:ENOG410PMNB; InterPro:IPR013149,IPR011032,IPR020843,IPR036291; PFAM:PF00107; SMCOG1028:crotonyl-CoA reductase / alcohol dehydrogenase; antiSMASH:Cluster_3.6; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_31315S COG:Q; EggNog:ENOG410PWHU; InterPro:IPR001128,IPR017972,IPR002401,IPR036396; PFAM:PF00067; SMCOG1034:cytochrome P450; antiSMASH:Cluster_3.6; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_31316S COG:G; EggNog:ENOG410PVFG; InterPro:IPR014718,IPR008183,IPR011013; PFAM:PF01263; SECRETED:SignalP(1-19); antiSMASH:Cluster_3.6; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0016853 - isomerase activity [Evidence IEA]; go_function: GO:0030246 - carbohydrate binding [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_31317A COG:S; EggNog:ENOG410PX4W; InterPro:IPR005645,IPR029058; PFAM:PF02230,PF03959; antiSMASH:Cluster_3.6 AKAW2_31318A COG:S; EggNog:ENOG410PTH6; InterPro:IPR036864,IPR001138; PFAM:PF00172; antiSMASH:Cluster_3.6; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_31319S COG:S; EggNog:ENOG410PR7D; InterPro:IPR029063,IPR041698; PFAM:PF08241,PF13649; antiSMASH:Cluster_3.6 AKAW2_31320A COG:G; EggNog:ENOG410PW4X; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690,PF06609; SMCOG1005:Drug resistance transporter, EmrB/QacA; TransMembrane:14 (i56-82o94-111i123-143o149-173i180-200o212-232i252- 271o277-300i320-340o360-378i390-408o414-437i449-474o526- 548i); antiSMASH:Cluster_3.6; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_31321A COG:S; EggNog:ENOG410PUXM; InterPro:IPR036852,IPR000209,IPR015500; PFAM:PF00082; antiSMASH:Cluster_3.6; go_function: GO:0004252 - serine-type endopeptidase activity [Evidence IEA]; go_function: GO:0008236 - serine-type peptidase activity [Evidence IEA]; go_process: GO:0006508 - proteolysis [Evidence IEA] AKAW2_31322A COG:S; EggNog:ENOG410PUXM; antiSMASH:Cluster_3.6 AKAW2_31323A COG:S; EggNog:ENOG410PP09; antiSMASH:Cluster_3.7 AKAW2_31324S COG:M; EggNog:ENOG410PUCD; InterPro:IPR002110,IPR036770,IPR020683; PFAM:PF13857,PF12796,PF00023,PF13637,PF13606; antiSMASH:Cluster_3.7; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_31325A COG:S; EggNog:ENOG410PGUH; antiSMASH:Cluster_3.7 AKAW2_31326A COG:Q; EggNog:ENOG410PKPR; InterPro:IPR016036,IPR016035,IPR016039,IPR042104, IPR014030,IPR011032,IPR013968,IPR013154,IPR001227, IPR032821,IPR014031,IPR006162,IPR014043,IPR020806, IPR020807,IPR020843,IPR020841,IPR009081,IPR029063, IPR036736,IPR036291,IPR013217; PFAM:PF16197,PF00109,PF13489,PF13649,PF08240, PF02801,PF00698,PF06080,PF13847,PF14765,PF08242,PF08241; SMCOG1022:Beta-ketoacyl synthase; antiSMASH:Cluster_3.7; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0016740 - transferase activity [Evidence IEA]; go_function: GO:0016746 - transferase activity, transferring acyl groups [Evidence IEA]; go_function: GO:0031177 - phosphopantetheine binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_31327A COG:S; EggNog:ENOG410PUSJ; InterPro:IPR036864,IPR001138; PFAM:PF00172; TransMembrane:2 (i188-204o210-227i); antiSMASH:Cluster_3.7; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_31328S COG:G; EggNog:ENOG410PW4X; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690,PF06609; SMCOG1005:Drug resistance transporter, EmrB/QacA; TransMembrane:14 (o20-46i58-75o87-106i118-139o145-168i175-196o208-231i243- 262o282-304i316-340o346-364i376-402o408-435i491-512o); antiSMASH:Cluster_3.7; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_31329S COG:D; EggNog:ENOG410PPDA; InterPro:IPR012094,IPR011063,IPR012795; PFAM:PF01171; antiSMASH:Cluster_3.7; go_function: GO:0000166 - nucleotide binding [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016879 - ligase activity, forming carbon-nitrogen bonds [Evidence IEA]; go_process: GO:0008033 - tRNA processing [Evidence IEA] AKAW2_31330A COG:T; EggNog:ENOG410PGG5; InterPro:IPR000219,IPR035899,IPR021895; PFAM:PF12015,PF00621; antiSMASH:Cluster_3.7; go_function: GO:0005085 - guanyl-nucleotide exchange factor activity [Evidence IEA] AKAW2_31331S COG:U; EggNog:ENOG410PFNE; InterPro:IPR016024,IPR035999,IPR023394,IPR032691, IPR000904; PFAM:PF12783,PF01369; go_function: GO:0005086 - ARF guanyl-nucleotide exchange factor activity [Evidence IEA]; go_process: GO:0032012 - regulation of ARF protein signal transduction [Evidence IEA] AKAW2_31332A BUSCO:EOG09261XNU; COG:A; EggNog:ENOG410PHN7; InterPro:IPR011990,IPR003107,IPR019734,IPR013026; PFAM:PF13181; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0006396 - RNA processing [Evidence IEA] AKAW2_31333S BUSCO:EOG09264IMV; COG:C; EggNog:ENOG410PHRZ; InterPro:IPR002699; PFAM:PF01813; go_function: GO:0042626 - ATPase-coupled transmembrane transporter activity [Evidence IEA] AKAW2_31334A COG:A; EggNog:ENOG410PGNM; InterPro:IPR000504,IPR012677,IPR035979; PFAM:PF00076; go_function: GO:0003676 - nucleic acid binding [Evidence IEA] AKAW2_31335A BUSCO:EOG09260APA; COG:O; EggNog:ENOG410PGTH; InterPro:IPR016024,IPR011989,IPR033162,IPR022577; PFAM:PF12612; go_function: GO:0005096 - GTPase activator activity [Evidence IEA]; go_function: GO:0048487 - beta-tubulin binding [Evidence IEA]; go_process: GO:0007021 - tubulin complex assembly [Evidence IEA]; go_process: GO:0007023 - post-chaperonin tubulin folding pathway [Evidence IEA] AKAW2_31337A COG:S; EggNog:ENOG410PTZE AKAW2_31338A BUSCO:EOG09260NHN; COG:T; EggNog:ENOG410PHX3; InterPro:IPR037778,IPR017441,IPR011072,IPR008271, IPR000008,IPR002219,IPR000719,IPR011009,IPR037312, IPR036274; PFAM:PF00433,PF00168,PF00130,PF07714,PF02185, PF00069; SMCOG1030:serine/threonine protein kinase; antiSMASH:Cluster_3.8; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0004697 - protein kinase C activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA]; go_process: GO:0007165 - signal transduction [Evidence IEA]; go_process: GO:0009272 - fungal-type cell wall biogenesis [Evidence IEA]; go_process: GO:0035556 - intracellular signal transduction [Evidence IEA] AKAW2_31339A COG:G; EggNog:ENOG410PIWB; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; SMCOG1106:major facilitator transporter; TransMembrane:12 (i100-124o130-152i164-180o186-206i218-239o251-271i316- 341o353-369i381-400o406-428i440-462o468-488i); antiSMASH:Cluster_3.8; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_31340S COG:J; EggNog:ENOG410PPPT; InterPro:IPR001253,IPR006196,IPR012340,IPR039294; PFAM:PF01176; antiSMASH:Cluster_3.8; go_function: GO:0003723 - RNA binding [Evidence IEA]; go_function: GO:0003743 - translation initiation factor activity [Evidence IEA]; go_process: GO:0006413 - translational initiation [Evidence IEA] AKAW2_31341A CAZy:GT58; COG:G; EggNog:ENOG410PJ0Q; InterPro:IPR007873; PFAM:PF05208; TransMembrane:10 (i21-40o73-89i101-121o141-162i169-199o205-223i264-283o310- 327i334-359o379-399i); antiSMASH:Cluster_3.8; go_function: GO:0000030 - mannosyltransferase activity [Evidence IEA] AKAW2_31342A COG:S; EggNog:ENOG410PY4J; SECRETED:SignalP(1-30); antiSMASH:Cluster_3.8 AKAW2_31343S COG:G,T; EggNog:ENOG410PHPW; InterPro:IPR004843,IPR006186; PFAM:PF00149; antiSMASH:Cluster_3.8; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_31344A COG:K; EggNog:ENOG410PJZG; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; TransMembrane:2 (o513-531i572-594o); antiSMASH:Cluster_3.8; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_31345A COG:Q; EggNog:ENOG410QE5D; InterPro:IPR000873,IPR020845,IPR009081,IPR006162, IPR036291,IPR036736,IPR010080,IPR013120,IPR042099, IPR025110; PFAM:PF00501,PF01073,PF13193,PF00550,PF01370, PF07993; SMCOG1002:AMP-dependent synthetase and ligase; antiSMASH:Cluster_3.8 AKAW2_31346S COG:E; EggNog:ENOG410PFSG; InterPro:IPR004839,IPR015424,IPR015421,IPR015422; PFAM:PF00155; SMCOG1109:8-amino-7-oxononanoate synthase; antiSMASH:Cluster_3.8; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0030170 - pyridoxal phosphate binding [Evidence IEA]; go_process: GO:0009058 - biosynthetic process [Evidence IEA] AKAW2_31347S COG:S; EggNog:ENOG410PH56; InterPro:IPR034443; antiSMASH:Cluster_3.8 AKAW2_31348A COG:K; EggNog:ENOG410PJM3; InterPro:IPR036236,IPR036864,IPR007219,IPR013087, IPR001138; PFAM:PF00172,PF04082; TransMembrane:1 (o930-949i); antiSMASH:Cluster_3.8; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_31349S COG:T,U; EggNog:ENOG410PQG5; InterPro:IPR000261,IPR011992; PFAM:PF12763; antiSMASH:Cluster_3.8; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_31350S COG:S; EggNog:ENOG410PM2Y; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172; TransMembrane:1 (o636-655i); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_31351A COG:S; EggNog:ENOG410PGVK AKAW2_31352S BUSCO:EOG09260V5Q; COG:A; EggNog:ENOG410PIIN; InterPro:IPR015507,IPR024576,IPR029063,IPR002877, IPR012920,IPR028589; PFAM:PF01728,PF07780,PF11861; go_component: GO:0005634 - nucleus [Evidence IEA]; go_function: GO:0008168 - methyltransferase activity [Evidence IEA]; go_function: GO:0008649 - rRNA methyltransferase activity [Evidence IEA]; go_process: GO:0001510 - RNA methylation [Evidence IEA]; go_process: GO:0006364 - rRNA processing [Evidence IEA]; go_process: GO:0031167 - rRNA methylation [Evidence IEA]; go_process: GO:0032259 - methylation [Evidence IEA] AKAW2_31353A COG:U; EggNog:ENOG410PR3K; InterPro:IPR013923; PFAM:PF08614 AKAW2_31354S COG:U; EggNog:ENOG410PFIM; InterPro:IPR005225,IPR001806,IPR027417; PFAM:PF04670,PF00025,PF08477,PF00071,PF01926; go_function: GO:0003924 - GTPase activity [Evidence IEA]; go_function: GO:0005525 - GTP binding [Evidence IEA] AKAW2_31355S COG:E,G; EggNog:ENOG410PGJD; InterPro:IPR025016; PFAM:PF13127; TransMembrane:2 (i20-44o56-75i) AKAW2_31356S COG:E,G; EggNog:ENOG410PGJD; InterPro:IPR000620; TransMembrane:7 (o12-32i39-56o84-105i117-143o155-176i183-203o209-226i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA] AKAW2_31357A COG:T; EggNog:ENOG410PJYR; InterPro:IPR001849,IPR011993; PFAM:PF15410,PF00169 AKAW2_31359S CAZy:GT15; COG:G; EggNog:ENOG410PFFX; InterPro:IPR029044,IPR002685; PFAM:PF01793; TransMembrane:1 (i48-71o); go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0000030 - mannosyltransferase activity [Evidence IEA]; go_process: GO:0006486 - protein glycosylation [Evidence IEA] AKAW2_31360S COG:S; EggNog:ENOG410PPJ7; TransMembrane:1 (o488-509i) AKAW2_31361S BUSCO:EOG09264XT5; COG:U; EggNog:ENOG410PJH4; InterPro:IPR000156,IPR011993; PFAM:PF00638; go_process: GO:0046907 - intracellular transport [Evidence IEA] AKAW2_31362S COG:K; EggNog:ENOG410PJJH; InterPro:IPR005033,IPR016665,IPR027353,IPR038704; PFAM:PF03366,PF17035; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_31363A COG:T; EggNog:ENOG410PPRT; InterPro:IPR036249,IPR024253,IPR001200; PFAM:PF02114; go_process: GO:0008277 - regulation of G protein-coupled receptor signaling pathway [Evidence IEA] AKAW2_31364A BUSCO:EOG092645OU; COG:S; EggNog:ENOG410PI4N; InterPro:IPR001632,IPR016346,IPR036322,IPR015943, IPR001680,IPR019775,IPR020472,IPR017986; PFAM:PF00400; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0007165 - signal transduction [Evidence IEA] AKAW2_31365S BUSCO:EOG09260H6E; COG:O; EggNog:ENOG410PJJR; InterPro:IPR016024,IPR002893; PFAM:PF01753 AKAW2_31366A COG:Q; EggNog:ENOG410PIPM; InterPro:IPR026992,IPR027443,IPR005123; PFAM:PF03171,PF14226; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_31367S COG:S; EggNog:ENOG410PTN9; InterPro:IPR009643; PFAM:PF06825; go_function: GO:0003714 - transcription corepressor activity [Evidence IEA] AKAW2_31368A COG:O; EggNog:ENOG410PGPE; InterPro:IPR017937,IPR011679,IPR036249,IPR005788, IPR013766,IPR036356; PFAM:PF13098,PF00085,PF07749; SECRETED:SignalP(1-19); go_component: GO:0005783 - endoplasmic reticulum [Evidence IEA]; go_function: GO:0003756 - protein disulfide isomerase activity [Evidence IEA] AKAW2_31369A BUSCO:EOG09260BFE; COG:S; EggNog:ENOG410PG77; InterPro:IPR022039,IPR006084,IPR006085,IPR029060, IPR022040,IPR037314; PFAM:PF00752,PF12247,PF12246; go_function: GO:0004518 - nuclease activity [Evidence IEA] AKAW2_31370S COG:S; EggNog:ENOG410PJXJ; InterPro:IPR007568; PFAM:PF04479; SECRETED:SignalP(1-17); TransMembrane:7 (n2-9c18/19o42-62i74-95o115-138i150-168o188-211i223- 241o261-282i); go_component: GO:0016021 - integral component of membrane [Evidence IEA] AKAW2_31371S COG:S; EggNog:ENOG410PFZU; InterPro:IPR036322,IPR015943,IPR019775,IPR001680, IPR017986; PFAM:PF00400; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_31372A BUSCO:EOG09260KNR; COG:J; EggNog:ENOG410PGBH; InterPro:IPR025313,IPR027417,IPR001650,IPR014014, IPR014001,IPR011545; PFAM:PF04851,PF00270,PF00271,PF13959; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0004386 - helicase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA] AKAW2_31373A COG:H; EggNog:ENOG410PHBR; InterPro:IPR042176,IPR003721,IPR014729; PFAM:PF02569; go_function: GO:0004592 - pantoate-beta-alanine ligase activity [Evidence IEA]; go_process: GO:0015940 - pantothenate biosynthetic process [Evidence IEA] AKAW2_31375S COG:I; EggNog:ENOG410PKD9; InterPro:IPR022284,IPR041728,IPR002123; PFAM:PF01553; go_function: GO:0008374 - O-acyltransferase activity [Evidence IEA]; go_function: GO:0016746 - transferase activity, transferring acyl groups [Evidence IEA]; go_process: GO:0044255 - cellular lipid metabolic process [Evidence IEA] AKAW2_31376A COG:S; EggNog:ENOG410PN61; InterPro:IPR039535,IPR011047; PFAM:PF05935,PF14269; SECRETED:SignalP(1-23) AKAW2_31377S COG:S; EggNog:ENOG410PT5N AKAW2_31378S COG:S; EggNog:ENOG410PIST; InterPro:IPR022124; PFAM:PF12396 AKAW2_31379A COG:T; EggNog:ENOG410QDWB; InterPro:IPR004358,IPR003594,IPR003661,IPR036890, IPR036097,IPR011006,IPR001789,IPR029016,IPR005467; PFAM:PF00512,PF02518,PF00072; go_function: GO:0000155 - phosphorelay sensor kinase activity [Evidence IEA]; go_function: GO:0016772 - transferase activity, transferring phosphorus-containing groups [Evidence IEA]; go_process: GO:0000160 - phosphorelay signal transduction system [Evidence IEA]; go_process: GO:0007165 - signal transduction [Evidence IEA]; go_process: GO:0016310 - phosphorylation [Evidence IEA] AKAW2_31380A COG:K; EggNog:ENOG410PJPW; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; TransMembrane:1 (o448-467i); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_31381A COG:G; EggNog:ENOG410Q8MB; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i48-65o89-109i116-137o149-169i181-200o212-231i274- 296o316-334i346-365o371-394i406-427o439-459i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_31382A COG:M; EggNog:ENOG410PKKZ; InterPro:IPR002110,IPR036770,IPR001810,IPR036047, IPR020683; PFAM:PF13857,PF12796,PF00023,PF13637,PF13606; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_31383S COG:T; EggNog:ENOG410PNTH; InterPro:IPR000719,IPR011009,IPR001245; PFAM:PF07714,PF00069; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_31384S COG:T; EggNog:ENOG410PPV9; InterPro:IPR000719,IPR011009,IPR008266; PFAM:PF07714,PF00069; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_31386S COG:C; EggNog:ENOG410PJPT; InterPro:IPR001709,IPR012292,IPR001433,IPR009050, IPR017927,IPR008333,IPR023950,IPR000971,IPR017938, IPR039261; PFAM:PF00042,PF00175,PF00970; go_function: GO:0008941 - nitric oxide dioxygenase activity [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0019825 - oxygen binding [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_function: GO:0071949 - FAD binding [Evidence IEA]; go_process: GO:0051409 - response to nitrosative stress [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_31387A COG:E; EggNog:ENOG410PJD8; InterPro:IPR015424,IPR002129; go_function: GO:0016831 - carboxy-lyase activity [Evidence IEA]; go_function: GO:0030170 - pyridoxal phosphate binding [Evidence IEA]; go_process: GO:0019752 - carboxylic acid metabolic process [Evidence IEA] AKAW2_31388S COG:S; EggNog:ENOG410PHYQ; InterPro:IPR036864,IPR021858,IPR001138; PFAM:PF00172; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_31389S COG:G; EggNog:ENOG410PJJ1; InterPro:IPR005829,IPR005828,IPR003663,IPR036259, IPR020846; PFAM:PF00083,PF07690; TransMembrane:9 (o25-46i58-83o150-169i269-294o306-327i334-356o368-393i405- 428o434-454i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_31390A COG:Q; EggNog:ENOG410PM4N; InterPro:IPR036291,IPR002347; PFAM:PF08659,PF00106; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_31391S COG:E; EggNog:ENOG410PJIE; InterPro:IPR036526,IPR044149,IPR000132,IPR003010; PFAM:PF00795; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_process: GO:0006807 - nitrogen compound metabolic process [Evidence IEA] AKAW2_31392S COG:S; EggNog:ENOG410PR4M; InterPro:IPR021514; PFAM:PF11374; TransMembrane:4 (i100-122o134-155i197-218o581-604i) AKAW2_31393A COG:U; EggNog:ENOG410QDYJ; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i124-148o160-180i192-213o219-241i253-275o287-312i360- 379o399-419i440-459o465-489i509-526o532-552i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_31394S COG:G; EggNog:ENOG410PJ3A; InterPro:IPR005829,IPR005828,IPR003663,IPR036259, IPR020846; PFAM:PF00083,PF07690; TransMembrane:11 (n27-37c42/43o78-97i109-127o133-155i162-184o204-222i294- 316o336-356i363-384o404-423i435-456o476-494i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_31395S COG:F; EggNog:ENOG410PIQ3; InterPro:IPR036412,IPR009453; PFAM:PF06437; go_function: GO:0000287 - magnesium ion binding [Evidence IEA]; go_function: GO:0050483 - IMP 5'-nucleotidase activity [Evidence IEA]; go_process: GO:0006190 - inosine salvage [Evidence IEA]; go_process: GO:0009117 - nucleotide metabolic process [Evidence IEA] AKAW2_31396S COG:S; EggNog:ENOG410PPZF; InterPro:IPR036188,IPR023753; PFAM:PF07992,PF00070; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_31397A COG:G; EggNog:ENOG410PI6N; InterPro:IPR022953,IPR035966,IPR009161,IPR000023, IPR015912; PFAM:PF00365; go_component: GO:0005737 - cytoplasm [Evidence IEA]; go_function: GO:0003872 - 6-phosphofructokinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006002 - fructose 6-phosphate metabolic process [Evidence IEA]; go_process: GO:0006096 - glycolytic process [Evidence IEA] AKAW2_31399A COG:M; EggNog:ENOG410PHGT AKAW2_31400A CAZy:AA7; COG:C; EggNog:ENOG410PVKJ; InterPro:IPR006094,IPR036318,IPR016169,IPR016166, IPR016167,IPR012951; PFAM:PF08031,PF01565; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_function: GO:0071949 - FAD binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_31401S COG:S; EggNog:ENOG410PVR9; InterPro:IPR010354,IPR036188; PFAM:PF06100; go_function: GO:0050151 - oleate hydratase activity [Evidence IEA]; go_function: GO:0071949 - FAD binding [Evidence IEA]; go_process: GO:0006631 - fatty acid metabolic process [Evidence IEA] AKAW2_31402A COG:S; EggNog:ENOG410PQ0F; InterPro:IPR027377; PFAM:PF13695 AKAW2_31403S COG:K; EggNog:ENOG410PK46; InterPro:IPR019313; PFAM:PF10156; go_component: GO:0016592 - mediator complex [Evidence IEA]; go_function: GO:0003712 - transcription coregulator activity [Evidence IEA]; go_process: GO:0006357 - regulation of transcription by RNA polymerase II [Evidence IEA] AKAW2_31404S COG:T; EggNog:ENOG410PJP7; InterPro:IPR000719,IPR011009; PFAM:PF07714,PF00069; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_31405S COG:P; EggNog:ENOG410PNV3; InterPro:IPR036874,IPR015892,IPR001765; PFAM:PF00484; go_function: GO:0004089 - carbonate dehydratase activity [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0015976 - carbon utilization [Evidence IEA] AKAW2_31406A COG:S; EggNog:ENOG410PN7Z; TransMembrane:7 (o12-32i44-70o90-114i126-156o176-200i212-232o252-273i) AKAW2_31407S COG:S; EggNog:ENOG410PMJ2; InterPro:IPR005123; PFAM:PF13640; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_31408A COG:S; EggNog:ENOG410PNEE; InterPro:IPR003480,IPR023213; PFAM:PF02458; go_function: GO:0016747 - transferase activity, transferring acyl groups other than amino-acyl groups [Evidence IEA] AKAW2_31409S COG:S; EggNog:ENOG410PNI8; TransMembrane:7 (o30-49i61-84o104-126i138-163o189-211i223-244o264-286i) AKAW2_31410A COG:S; EggNog:ENOG410PIJP; InterPro:IPR004104,IPR000683,IPR036291; PFAM:PF02894,PF01408; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA] AKAW2_31411A COG:S; EggNog:ENOG410PU0E AKAW2_31412S COG:S; EggNog:ENOG410PZAI AKAW2_31413S COG:P; EggNog:ENOG410Q1TS; InterPro:IPR044089,IPR002523; PFAM:PF01544; TransMembrane:2 (i312-330o350-371i); go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0015095 - magnesium ion transmembrane transporter activity [Evidence IEA]; go_function: GO:0046873 - metal ion transmembrane transporter activity [Evidence IEA]; go_process: GO:0030001 - metal ion transport [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA]; go_process: GO:1903830 - magnesium ion transmembrane transport [Evidence IEA] AKAW2_31414A COG:Q; EggNog:ENOG410PKUU; InterPro:IPR001128,IPR002401,IPR036396; PFAM:PF00067; SECRETED:SignalP(1-17); go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_31415A COG:Q; EggNog:ENOG410PNXK; InterPro:IPR036291,IPR002347; PFAM:PF08659,PF00106,PF13561; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_31416A COG:Q; EggNog:ENOG410PG34; InterPro:IPR001128,IPR017972,IPR002401,IPR036396; PFAM:PF00067; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_31417S COG:Q; EggNog:ENOG410PVPB; InterPro:IPR013154,IPR013149,IPR002328,IPR036291, IPR011032,IPR029752,IPR020843; PFAM:PF00107,PF08240; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_31418S COG:S; EggNog:ENOG410PSR3; InterPro:IPR036047,IPR032675; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_31419A CAZy:GH76; COG:G; EggNog:ENOG410PFRH; InterPro:IPR014480,IPR008928,IPR005198; PFAM:PF03663; SECRETED:SignalP(1-18); TransMembrane:1 (i428-450o); go_function: GO:0008496 - mannan endo-1,6-alpha-mannosidase activity [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA]; go_process: GO:0016052 - carbohydrate catabolic process [Evidence IEA] AKAW2_31420A COG:G; EggNog:ENOG410PMBC; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i54-71o91-112i124-144o150-171i183-202o214-234i254- 272o284-304i316-337o343-360i367-385o391-412i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_31421S COG:K; EggNog:ENOG410PFTN; InterPro:IPR008422,IPR036236,IPR001356,IPR009057, IPR017970,IPR013087; PFAM:PF00046,PF05920; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_31422S COG:S; EggNog:ENOG410PJV4; InterPro:IPR000073,IPR029058,IPR013595; MEROPS:MER0000441; PFAM:PF08386; TransMembrane:1 (o358-378i) AKAW2_31423A COG:P; EggNog:ENOG410PHHN; InterPro:IPR001734,IPR038377,IPR031155; PFAM:PF00474; TransMembrane:15 (o20-44i65-88o100-120i141-169o175-194i201-220o263-286i298- 325o364-390i411-431o437-459i466-485o505-525i575-593o613- 634i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0015204 - urea transmembrane transporter activity [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA]; go_process: GO:0071918 - urea transmembrane transport [Evidence IEA] AKAW2_31424S COG:C; EggNog:ENOG410PGED; InterPro:IPR011251,IPR016215,IPR036661; PFAM:PF00296; go_function: GO:0004497 - monooxygenase activity [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_31425A COG:S; EggNog:ENOG410PGMK; InterPro:IPR016274,IPR033379,IPR000560,IPR029033; PFAM:PF00328; go_function: GO:0016791 - phosphatase activity [Evidence IEA] AKAW2_31426A SECRETED:SignalP(1-19) AKAW2_31427A COG:S; EggNog:ENOG410Q1Y1; TransMembrane:2 (i185-204o210-229i) AKAW2_31428A COG:O; EggNog:ENOG410PIXI; InterPro:IPR021109,IPR033876,IPR001461,IPR001969, IPR033121; MEROPS:MER0003669; PFAM:PF00026; SECRETED:SignalP(1-18); go_function: GO:0004190 - aspartic-type endopeptidase activity [Evidence IEA]; go_process: GO:0006508 - proteolysis [Evidence IEA] AKAW2_31429A COG:K; EggNog:ENOG410PM5K; InterPro:IPR012349,IPR007396; PFAM:PF04299 AKAW2_31430A COG:S; EggNog:ENOG410PS88; InterPro:IPR022596,IPR023041; PFAM:PF11710,PF11970; TransMembrane:7 (n2-10c17/18o47-69i89-111o131-153i165-187o214-234i260- 280o292-313i) AKAW2_31431S TransMembrane:1 (o20-37i) AKAW2_31432A COG:S; EggNog:ENOG410QE8F; InterPro:IPR036188,IPR002938; PFAM:PF01494; TransMembrane:1 (i12-37o); go_function: GO:0071949 - FAD binding [Evidence IEA] AKAW2_31433A COG:S; EggNog:ENOG410PMWE; TransMembrane:7 (o20-41i53-75o102-120i132-154o178-201i213-235o247-271i) AKAW2_31434S COG:G; EggNog:ENOG410QDJ6; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i50-71o91-109i146-166o178-197i209-231o277-300i307- 327o333-354i361-381o387-409i421-438o458-477i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_31435S COG:T; EggNog:ENOG410PVXJ; InterPro:IPR000719,IPR011009,IPR017441; PFAM:PF07714,PF00069; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_31436A COG:Q; EggNog:ENOG410Q24T; InterPro:IPR001128,IPR017972,IPR002401,IPR036396; PFAM:PF00067; TransMembrane:1 (o12-31i); go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_31437A COG:S; EggNog:ENOG410PU8H; InterPro:IPR011118,IPR029058; PFAM:PF07519; SECRETED:SignalP(1-16) AKAW2_31438A COG:L; EggNog:ENOG410PKWZ; InterPro:IPR036616,IPR036420,IPR001357,IPR012317, IPR008893,IPR004102,IPR036930; PFAM:PF12738,PF00644,PF00533,PF02877,PF05406; go_function: GO:0003950 - NAD+ ADP-ribosyltransferase activity [Evidence IEA]; go_process: GO:0006471 - protein ADP-ribosylation [Evidence IEA] AKAW2_31439A COG:G; EggNog:ENOG410Q1FC; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i143-164o176-199i211-228o234-257i269-288o300-320i376- 400o412-434i455-474o480-505i512-537o549-571i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_31440A COG:H; EggNog:ENOG410PMYW; InterPro:IPR003710,IPR013752,IPR036291,IPR013332, IPR008927,IPR013328; PFAM:PF02558,PF08546; go_function: GO:0008677 - 2-dehydropantoate 2-reductase activity [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0015940 - pantothenate biosynthetic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_31441A COG:S; EggNog:ENOG410PKRT; InterPro:IPR006694; PFAM:PF04116; TransMembrane:3 (i63-81o87-105i171-191o); go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0008610 - lipid biosynthetic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_31442S CAZy:AA3; COG:E; EggNog:ENOG410PJ5E; InterPro:IPR012132,IPR036188,IPR000172,IPR007867; PFAM:PF05199,PF00732; SECRETED:SignalP(1-20); go_function: GO:0016614 - oxidoreductase activity, acting on CH-OH group of donors [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_31443A COG:S; EggNog:ENOG410Q1NQ AKAW2_31444S COG:Q; EggNog:ENOG410PKZW; InterPro:IPR013154,IPR013149,IPR036291,IPR011032, IPR020843; PFAM:PF00107,PF08240,PF13602; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_31445A COG:I; EggNog:ENOG410PI9K; InterPro:IPR016035,IPR002642; PFAM:PF01735; SECRETED:SignalP(1-16); go_function: GO:0004620 - phospholipase activity [Evidence IEA]; go_process: GO:0009395 - phospholipid catabolic process [Evidence IEA] AKAW2_31446A COG:G; EggNog:ENOG410PFE6; InterPro:IPR011701,IPR001958,IPR036259,IPR020846; PFAM:PF00083,PF07690; TransMembrane:12 (i40-64o76-96i108-128o134-154i166-184o196-216i268-294o306- 327i347-368o374-395i402-428o440-460i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_31447A COG:S; EggNog:ENOG410PRAE; InterPro:IPR021765; PFAM:PF11807; TransMembrane:1 (i40-59o); go_process: GO:0043386 - mycotoxin biosynthetic process [Evidence IEA] AKAW2_31448A COG:S; EggNog:ENOG410PQ1B; TransMembrane:7 (o6-29i41-63o83-107i119-139o159-182i194-211o249-272i) AKAW2_31449S COG:E; EggNog:ENOG410PFXK; InterPro:IPR002293; PFAM:PF00324,PF13520; TransMembrane:8 (i49-72o84-109i130-154o174-196i203-225o245-263i284- 313o333-354i); go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_31450S COG:S; EggNog:ENOG410PQZM; InterPro:IPR000182,IPR016181; PFAM:PF13508,PF00583; go_function: GO:0008080 - N-acetyltransferase activity [Evidence IEA] AKAW2_31451S CAZy:AA3; COG:E; EggNog:ENOG410PJHS; InterPro:IPR012132,IPR000172,IPR036188; PFAM:PF01266,PF00732; TransMembrane:1 (o6-25i); go_function: GO:0016614 - oxidoreductase activity, acting on CH-OH group of donors [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_31452S COG:E; EggNog:ENOG410PJHS; InterPro:IPR007867,IPR012132,IPR036188; PFAM:PF05199; go_function: GO:0016614 - oxidoreductase activity, acting on CH-OH group of donors [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_31453S COG:S; EggNog:ENOG410PQ5B; InterPro:IPR000073,IPR029058; PFAM:PF12697 AKAW2_31454A COG:O; EggNog:ENOG410PR3Z; InterPro:IPR001179; PFAM:PF00254; go_function: GO:0003755 - peptidyl-prolyl cis-trans isomerase activity [Evidence IEA] AKAW2_31456A COG:E; EggNog:ENOG410PPSZ; InterPro:IPR005645,IPR029058; PFAM:PF03959 AKAW2_31457A COG:S; EggNog:ENOG410PVBT AKAW2_31458A COG:K; EggNog:ENOG410PM5K; InterPro:IPR012349,IPR007396; PFAM:PF04299 AKAW2_31459S COG:F; EggNog:ENOG410PRM8; InterPro:IPR017926,IPR029062; MEROPS:MER0043475 AKAW2_31462A COG:S; EggNog:ENOG410PK65 AKAW2_31463A COG:M; EggNog:ENOG410PKAU; InterPro:IPR002110,IPR027417,IPR007111,IPR036770, IPR020683; PFAM:PF05729,PF12796,PF00023,PF13606,PF13637; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_31464A COG:S; EggNog:ENOG410PYKN AKAW2_31465A COG:S; EggNog:ENOG410PRJR AKAW2_31466A COG:S; EggNog:ENOG410PT48 AKAW2_31468S COG:S; EggNog:ENOG410PGVQ; InterPro:IPR029063,IPR002877; PFAM:PF01728; go_function: GO:0008168 - methyltransferase activity [Evidence IEA]; go_process: GO:0032259 - methylation [Evidence IEA] AKAW2_31469S COG:S; EggNog:ENOG410PRVU AKAW2_31471S COG:S; EggNog:ENOG410PNUZ; InterPro:IPR031348 AKAW2_31472A COG:T; EggNog:ENOG410PXX8; InterPro:IPR000210,IPR011333; PFAM:PF00651; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_31474S COG:S; EggNog:ENOG410Q1I8 AKAW2_31475A COG:K; EggNog:ENOG410Q1WU; InterPro:IPR036864,IPR001138; PFAM:PF00172; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_31476A COG:S; EggNog:ENOG410PKVH AKAW2_31477S COG:S; EggNog:ENOG410Q1DK; InterPro:IPR036879,IPR002100; PFAM:PF00319; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0046983 - protein dimerization activity [Evidence IEA] AKAW2_31478A COG:K; EggNog:ENOG410Q2SA; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_31479S COG:K; EggNog:ENOG410Q1WU; InterPro:IPR036864,IPR007219,IPR001138; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_31480S COG:S; EggNog:ENOG410PUUG; InterPro:IPR011009 AKAW2_31483A COG:O; EggNog:ENOG410PIVI; InterPro:IPR001623,IPR036869,IPR018253; PFAM:PF00226 AKAW2_31484A InterPro:IPR036879; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0046983 - protein dimerization activity [Evidence IEA] AKAW2_31485S SECRETED:SignalP(1-22) AKAW2_31486A COG:Z; EggNog:ENOG410QEDU; InterPro:IPR011990,IPR019734,IPR013026,IPR002151; PFAM:PF13374,PF13176,PF13424; TransMembrane:1 (o593-612i); go_component: GO:0005871 - kinesin complex [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_31487A COG:Z; EggNog:ENOG410QEDU; InterPro:IPR000845,IPR035994,IPR027417,IPR002182; PFAM:PF01048,PF00931; SECRETED:SignalP(1-25); go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0043531 - ADP binding [Evidence IEA]; go_process: GO:0009116 - nucleoside metabolic process [Evidence IEA] AKAW2_31491S TransMembrane:4 (i58-78o222-241i253-274o303-321i) AKAW2_31493S COG:S; EggNog:ENOG410Q0DS; InterPro:IPR022198; PFAM:PF12520 AKAW2_31496S COG:L; EggNog:ENOG410Q1Z8; TransMembrane:1 (o202-221i) AKAW2_31497A COG:Q; EggNog:ENOG410PPEB; InterPro:IPR002347,IPR036291,IPR020904; PFAM:PF00106,PF13561,PF08659,PF01370; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_31499A COG:S; EggNog:ENOG410PFU5; InterPro:IPR029063 AKAW2_31502S COG:S; EggNog:ENOG410PYK3 AKAW2_31503A COG:S; EggNog:ENOG410PK6N; InterPro:IPR036864,IPR001138; PFAM:PF00172; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_31504S COG:S; EggNog:ENOG410PYNS; InterPro:IPR011990; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_31505S InterPro:IPR036428; go_function: GO:0008124 - 4-alpha-hydroxytetrahydrobiopterin dehydratase activity [Evidence IEA]; go_process: GO:0006729 - tetrahydrobiopterin biosynthetic process [Evidence IEA] AKAW2_31506A COG:S; EggNog:ENOG410Q2E7; InterPro:IPR000719,IPR011009; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_31507S COG:S; EggNog:ENOG410PTET AKAW2_31508A COG:S; EggNog:ENOG410PGXJ; TransMembrane:6 (o25-43i55-73o79-101i113-137o157-174i186-204o) AKAW2_31510A COG:S; EggNog:ENOG410PJPF; TransMembrane:7 (o23-44i51-71o91-110i122-142o162-181i201-222o242-260i) AKAW2_31511S CAZy:CE10; COG:T; EggNog:ENOG410PM0V; InterPro:IPR019819,IPR002018,IPR029058; MEROPS:MER0033188; PFAM:PF00135; SECRETED:SignalP(1-20) AKAW2_31512A SECRETED:SignalP(1-22); TransMembrane:1 (i7-24o) AKAW2_31513S COG:K; EggNog:ENOG410Q58R; InterPro:IPR001005,IPR009057,IPR017877; PFAM:PF00249 AKAW2_31515S InterPro:IPR001841,IPR013083; PFAM:PF00097,PF13639 AKAW2_31516S COG:O; EggNog:ENOG410PN65; InterPro:IPR001841,IPR017907 AKAW2_31517S COG:S; EggNog:ENOG410PW16 AKAW2_31519S COG:M; EggNog:ENOG410Q1TJ; InterPro:IPR002110,IPR036770,IPR020683; PFAM:PF12796,PF00023,PF13637,PF13857; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_31521S COG:S; EggNog:ENOG410PHD3; InterPro:IPR032805; PFAM:PF13813; TransMembrane:4 (o120-145i212-229o241-263i284-303o) AKAW2_31522S COG:S; EggNog:ENOG410PKVH AKAW2_31523S COG:S; EggNog:ENOG410Q0BW AKAW2_31524S COG:A; EggNog:ENOG410PIUX; TransMembrane:2 (o160-180i231-248o) AKAW2_31525S COG:S; EggNog:ENOG410QEFM; InterPro:IPR036322,IPR015943,IPR001680,IPR019775, IPR020472,IPR017986; PFAM:PF12894,PF00400; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_31526A COG:S; EggNog:ENOG410Q2S9; InterPro:IPR000845,IPR035994,IPR027417,IPR007111; PFAM:PF05729,PF00400,PF12894; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_process: GO:0009116 - nucleoside metabolic process [Evidence IEA] AKAW2_31527S COG:S; EggNog:ENOG410PVTJ; InterPro:IPR013087,IPR021842; PFAM:PF11917; TransMembrane:1 (i323-344o) AKAW2_31528S InterPro:IPR001810,IPR036047,IPR032675; PFAM:PF00646,PF12937; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_31529S COG:S; EggNog:ENOG410Q28Y; InterPro:IPR021842 AKAW2_31531S COG:K; EggNog:ENOG410Q2F0; InterPro:IPR036236,IPR013087; PFAM:PF00096 AKAW2_31532S InterPro:IPR029404; PFAM:PF14811; go_process: GO:0030218 - erythrocyte differentiation [Evidence IEA] AKAW2_31535S InterPro:IPR029063 AKAW2_31536S COG:S; EggNog:ENOG410PT2C; InterPro:IPR000210,IPR011333; PFAM:PF00651; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_31538S COG:S; EggNog:ENOG410PPVJ AKAW2_31540S TransMembrane:1 (o12-28i) AKAW2_31541S COG:Q; EggNog:ENOG410PPEB; InterPro:IPR036291,IPR002347; PFAM:PF08659; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_31542A COG:L; EggNog:ENOG410Q1Z8; TransMembrane:1 (o202-221i) AKAW2_31543A COG:S; EggNog:ENOG410PMSY; InterPro:IPR010730; PFAM:PF06985 AKAW2_31544S COG:S; EggNog:ENOG410QDN7; InterPro:IPR000477,IPR036397,IPR012337,IPR005135, IPR002156,IPR036691,IPR043502; PFAM:PF00078,PF14529,PF00075; TransMembrane:1 (o1011-1030i); go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0004523 - RNA-DNA hybrid ribonuclease activity [Evidence IEA] AKAW2_31546A COG:S; EggNog:ENOG410Q0DS; InterPro:IPR022198; PFAM:PF12520 AKAW2_31548A TransMembrane:4 (i58-78o222-241i253-274o303-321i) AKAW2_31552S COG:S; EggNog:ENOG410PPS6; TransMembrane:2 (i49-69o104-124i) AKAW2_31553S CAZy:AA11; COG:S; EggNog:ENOG410QDDW AKAW2_31555S TransMembrane:1 (o12-37i) AKAW2_31556S InterPro:IPR036879; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0046983 - protein dimerization activity [Evidence IEA] AKAW2_31557S COG:O; EggNog:ENOG410PIVI; InterPro:IPR001623,IPR036869,IPR018253; PFAM:PF00226 AKAW2_31558S COG:Z; EggNog:ENOG410QEDU; InterPro:IPR035994; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_process: GO:0009116 - nucleoside metabolic process [Evidence IEA] AKAW2_31559S COG:S; EggNog:ENOG410PKVH AKAW2_31560S COG:A; EggNog:ENOG410PIUX; InterPro:IPR015943,IPR036322,IPR027417,IPR007111, IPR018391,IPR001680,IPR019775,IPR020472,IPR017986; PFAM:PF00400; TransMembrane:2 (o570-590i640-661o); go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_31561A COG:S; EggNog:ENOG410PNUZ; InterPro:IPR031348; PFAM:PF17111 AKAW2_31563A COG:S; EggNog:ENOG410PJ1P; InterPro:IPR031348; PFAM:PF17111; SECRETED:SignalP(1-21) AKAW2_31564A COG:S; EggNog:ENOG410PZ5E; InterPro:IPR011010,IPR013087,IPR021842; PFAM:PF11917; go_function: GO:0003677 - DNA binding [Evidence IEA] AKAW2_31565S COG:S; EggNog:ENOG410PUYG; InterPro:IPR029063; PFAM:PF13578,PF01596 AKAW2_31566A COG:Q; EggNog:ENOG410PUJ8; InterPro:IPR036249,IPR001853; PFAM:PF01323; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA] AKAW2_31567S COG:K; EggNog:ENOG410PNF0; InterPro:IPR002110,IPR020683,IPR036770; PFAM:PF13857,PF12796,PF00023,PF13637,PF13606; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_31568A COG:S; EggNog:ENOG410QDUB; InterPro:IPR000073,IPR029058; PFAM:PF05057,PF00561,PF07819 AKAW2_31569A COG:S; EggNog:ENOG410PW6M; TransMembrane:5 (i109-130o150-172i184-203o209-233i546-568o) AKAW2_31570A CAZy:GT69; COG:S; EggNog:ENOG410PGW7; InterPro:IPR021047; PFAM:PF11735; SECRETED:SignalP(1-27) AKAW2_31571S InterPro:IPR029063 AKAW2_31572S COG:S; EggNog:ENOG410PNX7; InterPro:IPR010679,IPR010621; PFAM:PF06863,PF06742; SECRETED:SignalP(1-28) AKAW2_31573A COG:G; EggNog:ENOG410PHC0; InterPro:IPR005829,IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:10 (i45-69o81-101i113-132o138-160i172-197o203-230i269- 296o316-340i361-380o386-414i); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_31574A COG:S; EggNog:ENOG410PSKI; InterPro:IPR000073,IPR029058; MEROPS:MER0213816; PFAM:PF12697 AKAW2_31575S TransMembrane:1 (o43-64i) AKAW2_31576A COG:S; EggNog:ENOG410PSK9; TransMembrane:5 (i36-62o97-125i146-169o181-202i521-543o) AKAW2_31577S COG:S; EggNog:ENOG410QE5I; InterPro:IPR023346; SECRETED:SignalP(1-21); antiSMASH:Cluster_3.10 AKAW2_31578S COG:G; EggNog:ENOG410PS5U; InterPro:IPR023271,IPR034294,IPR000425; PFAM:PF00230; TransMembrane:5 (i58-80o100-121i147-165o185-210i222-242o); antiSMASH:Cluster_3.10; go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0015267 - channel activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_31579A COG:O; EggNog:ENOG410PQI6; InterPro:IPR008978,IPR002068; PFAM:PF00011,PF17886; antiSMASH:Cluster_3.10 AKAW2_31580S InterPro:IPR007011; PFAM:PF04927; antiSMASH:Cluster_3.10 AKAW2_31581A COG:S; EggNog:ENOG410Q1CI; TransMembrane:3 (n2-10c15/16o39-60i72-94o106-125i); antiSMASH:Cluster_3.10 AKAW2_31582A COG:S; EggNog:ENOG410Q1CI; TransMembrane:3 (o13-30i42-63o90-114i); antiSMASH:Cluster_3.10 AKAW2_31583S COG:S; EggNog:ENOG410Q246; InterPro:IPR001077,IPR036388,IPR016461,IPR029063, IPR036390; PFAM:PF00891; SMCOG1042:O-methyltransferase; antiSMASH:Cluster_3.10; go_function: GO:0008168 - methyltransferase activity [Evidence IEA]; go_function: GO:0008171 - O-methyltransferase activity [Evidence IEA] AKAW2_31584S COG:F; EggNog:ENOG410Q17E; InterPro:IPR000845,IPR035994; PFAM:PF01048; antiSMASH:Cluster_3.10; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_process: GO:0009116 - nucleoside metabolic process [Evidence IEA] AKAW2_31585S COG:F; EggNog:ENOG410Q17E; InterPro:IPR027417; antiSMASH:Cluster_3.10 AKAW2_31586S COG:F; EggNog:ENOG410Q17E; InterPro:IPR002110,IPR036770,IPR020683; PFAM:PF12796,PF00023,PF13637,PF13857; antiSMASH:Cluster_3.10; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_31587A COG:E; EggNog:ENOG410PJ5E; InterPro:IPR007867,IPR012132,IPR000172,IPR036188; antiSMASH:Cluster_3.10; go_function: GO:0016614 - oxidoreductase activity, acting on CH-OH group of donors [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_31588A COG:E; EggNog:ENOG410PJ5E; InterPro:IPR012132,IPR000172,IPR036188; PFAM:PF00732; SECRETED:SignalP(1-20); antiSMASH:Cluster_3.10; go_function: GO:0016614 - oxidoreductase activity, acting on CH-OH group of donors [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_31589A COG:Q; EggNog:ENOG410PFZD; InterPro:IPR016036,IPR016035,IPR016039,IPR018201, IPR042104,IPR014030,IPR014031,IPR013968,IPR020845, IPR001227,IPR032821,IPR023213,IPR014043,IPR020806, IPR020807,IPR010071,IPR001242,IPR020843,IPR020841, IPR000873,IPR011032,IPR009081,IPR013149,IPR036736, IPR036291,IPR013120,IPR042099,IPR025110; PFAM:PF16197,PF00668,PF00550,PF02801,PF00698, PF00501,PF07993,PF00107,PF13193,PF13602,PF14765,PF00106, PF00109,PF08659; SMCOG1022:Beta-ketoacyl synthase; antiSMASH:Cluster_3.10; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein] synthase activity [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0016740 - transferase activity [Evidence IEA]; go_function: GO:0016746 - transferase activity, transferring acyl groups [Evidence IEA]; go_function: GO:0031177 - phosphopantetheine binding [Evidence IEA]; go_process: GO:0006633 - fatty acid biosynthetic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_31590A CAZy:AA7; COG:C; EggNog:ENOG410PJHR; InterPro:IPR006094,IPR036318,IPR016169,IPR016166, IPR016167,IPR012951; PFAM:PF08031,PF01565; SMCOG1138:FAD linked oxidase domain protein; antiSMASH:Cluster_3.10; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_function: GO:0071949 - FAD binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_31591S COG:Q; EggNog:ENOG410PNZR; InterPro:IPR001128,IPR002403,IPR017972,IPR036396; PFAM:PF00067; SMCOG1034:cytochrome P450; TransMembrane:1 (o20-38i); antiSMASH:Cluster_3.10; go_function: GO:0004497 - monooxygenase activity [Evidence IEA]; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_31592S COG:C; EggNog:ENOG410PVKV; InterPro:IPR036188,IPR002938; PFAM:PF01494; SMCOG1087:hypothetical protein; antiSMASH:Cluster_3.10; go_function: GO:0071949 - FAD binding [Evidence IEA] AKAW2_31593A COG:G; EggNog:ENOG410PFMD; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i133-156o162-182i203-220o232-250i262-284o296-319i369- 387o407-426i447-466o472-499i511-530o542-562i); antiSMASH:Cluster_3.10; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_31594S COG:Q; EggNog:ENOG410PG4C; InterPro:IPR002925,IPR029058; PFAM:PF01738; antiSMASH:Cluster_3.10; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_31595A COG:U; EggNog:ENOG410PW0W; InterPro:IPR011042,IPR011659; PFAM:PF07676; antiSMASH:Cluster_3.10 AKAW2_31596A COG:Q; EggNog:ENOG410PVPA; InterPro:IPR001128,IPR036396; SMCOG1034:cytochrome P450; TransMembrane:1 (o16-37i); antiSMASH:Cluster_3.10; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_31597S COG:S; EggNog:ENOG410PSMR; TransMembrane:4 (i15-40o60-79i91-117o129-150i) AKAW2_31598A COG:Q; EggNog:ENOG410PUA7; InterPro:IPR001128,IPR002403,IPR017972,IPR036396; PFAM:PF00067; TransMembrane:1 (i12-34o); go_function: GO:0004497 - monooxygenase activity [Evidence IEA]; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_31599S InterPro:IPR021858 AKAW2_31600S COG:S; EggNog:ENOG410PJVP; InterPro:IPR021858; PFAM:PF11951 AKAW2_31601S COG:G; EggNog:ENOG410PHVM; InterPro:IPR005829,IPR005828,IPR003663,IPR036259, IPR020846; PFAM:PF00083,PF07690; TransMembrane:11 (i31-56o85-104i116-134o140-160i172-191o203-225i312- 330o336-356i363-386o392-418i461-480o); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_31602S COG:S; EggNog:ENOG410PN1U; TransMembrane:1 (o12-31i) AKAW2_31603S COG:S; EggNog:ENOG410PN1U; TransMembrane:5 (o6-23i30-51o82-102i114-132o152-172i) AKAW2_31604A COG:E; EggNog:ENOG410PHGP; InterPro:IPR013057; PFAM:PF01490; TransMembrane:11 (i55-74o80-101i128-149o161-181i193-212o243-262i274- 296o316-335i356-377o389-411i423-447o) AKAW2_31605A COG:P; EggNog:ENOG410PGDX; InterPro:IPR020846,IPR005828,IPR036259; PFAM:PF07690,PF00083; TransMembrane:10 (o6-24i31-53o59-79i100-122o134-155i176-198o226-247i254- 275o281-306i349-368o); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_31606A COG:S; EggNog:ENOG410Q1MY; PFAM:PF16015; TransMembrane:2 (i120-151o157-180i) AKAW2_31607A COG:U; EggNog:ENOG410QE33; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:14 (i46-64o84-102i114-132o144-163i175-196o202-224i244- 263o275-293i314-337o343-369i376-396o402-427i439-462o482- 506i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_31608A COG:S; EggNog:ENOG410PSKF; TransMembrane:2 (o23-47i176-196o) AKAW2_31609A TransMembrane:1 (i7-26o) AKAW2_31610S TransMembrane:1 (o26-50i) AKAW2_31611A COG:S; EggNog:ENOG410PUXR; InterPro:IPR006652,IPR015915; PFAM:PF13418,PF01344,PF13415; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_31612A COG:K; EggNog:ENOG410Q2RT; InterPro:IPR036864,IPR001138; PFAM:PF00172; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_31613S COG:S; EggNog:ENOG410PUZ8; InterPro:IPR023213,IPR003480; PFAM:PF02458; go_function: GO:0016747 - transferase activity, transferring acyl groups other than amino-acyl groups [Evidence IEA] AKAW2_31614S COG:Q; EggNog:ENOG410PPUC; InterPro:IPR002347,IPR036291,IPR020904; PFAM:PF00106,PF13561,PF08659,PF01370; TransMembrane:1 (o26-44i); go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_31615S COG:S; EggNog:ENOG410PJ7E; InterPro:IPR000073,IPR029058; MEROPS:MER0209971; PFAM:PF12697 AKAW2_31616S COG:S; EggNog:ENOG410Q0MT; InterPro:IPR011008,IPR009799; PFAM:PF07110; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA] AKAW2_31617S COG:Q; EggNog:ENOG410PUDI; InterPro:IPR001128,IPR002401,IPR036396; PFAM:PF00067; TransMembrane:1 (o6-23i); go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_31618S COG:S; EggNog:ENOG410PXWG AKAW2_31619S COG:E; EggNog:ENOG410PHJU; InterPro:IPR004841; PFAM:PF13520,PF00324; TransMembrane:6 (n3-10c15/16o55-73i85-105o125-147i168-189o223-248i269- 289o); go_component: GO:0016020 - membrane [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_31620A COG:S; EggNog:ENOG410PVE8; InterPro:IPR036864,IPR001138; PFAM:PF00172; TransMembrane:1 (o542-562i); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_31621S COG:I; EggNog:ENOG410PJYC; InterPro:IPR042098,IPR003819; PFAM:PF02668; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_31622A COG:Q; EggNog:ENOG410Q2Y0; InterPro:IPR002347,IPR036291,IPR020904; PFAM:PF00106,PF13561,PF08659; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_31624A COG:C; EggNog:ENOG410Q1YF; InterPro:IPR018108,IPR023395; PFAM:PF00153; TransMembrane:2 (o16-37i83-102o) AKAW2_31625S COG:S; EggNog:ENOG410PGDR; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; TransMembrane:1 (o528-546i); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_31626A COG:S; EggNog:ENOG410PM4Z; InterPro:IPR007400; PFAM:PF04303 AKAW2_31627A COG:G; EggNog:ENOG410PKV4; InterPro:IPR005828,IPR003663,IPR036259,IPR020846; PFAM:PF00083,PF07690; SECRETED:SignalP(1-24); TransMembrane:11 (n6-14c19/20o64-82i94-115o121-140i152-170o182-203i270- 292o312-332i341-359o371-396i417-434o440-457i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_31628A COG:C,H; EggNog:ENOG410PREW; InterPro:IPR036188,IPR002938; PFAM:PF01494; go_function: GO:0071949 - FAD binding [Evidence IEA] AKAW2_31629A InterPro:IPR036663; go_function: GO:0003824 - catalytic activity [Evidence IEA] AKAW2_31630A COG:S; EggNog:ENOG410Q1T5; InterPro:IPR029063,IPR041698; PFAM:PF13649 AKAW2_31631A COG:S; EggNog:ENOG410QD96; InterPro:IPR029063 AKAW2_31632S COG:E; EggNog:ENOG410PU1S; InterPro:IPR024084,IPR000868,IPR036380; PFAM:PF00857,PF00180; go_function: GO:0016616 - oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_31633A COG:S; EggNog:ENOG410Q2WI AKAW2_31634S COG:S; EggNog:ENOG410Q014; InterPro:IPR002110,IPR020683,IPR036770; PFAM:PF13637,PF12796; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_31635S COG:V; EggNog:ENOG410PWX1; InterPro:IPR036291,IPR001509; PFAM:PF01370; go_function: GO:0003824 - catalytic activity [Evidence IEA] AKAW2_31636A COG:G; EggNog:ENOG410PMPY; TransMembrane:2 (i16-40o99-120i) AKAW2_40001S COG:E; EggNog:ENOG410PKIX; InterPro:IPR002293; PFAM:PF13520; TransMembrane:11 (o63-82i138-163o175-193i200-224o250-273i285-307o327- 360i388-410o416-438i458-480o486-507i); go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_40002A COG:P; EggNog:ENOG410PJRR; InterPro:IPR036188 AKAW2_40003A COG:Q; EggNog:ENOG410Q2WX; InterPro:IPR036188,IPR035959 AKAW2_40004A CAZy:AA7; COG:C; EggNog:ENOG410PW4N; InterPro:IPR016166,IPR006094,IPR036318; PFAM:PF01565; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_function: GO:0071949 - FAD binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_40005S CAZy:AA7; COG:C; EggNog:ENOG410PMMX; InterPro:IPR006094,IPR036318,IPR016166,IPR016167, IPR016169; PFAM:PF01565; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_function: GO:0071949 - FAD binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_40006A COG:S; EggNog:ENOG410PXGA; InterPro:IPR029069,IPR006683; PFAM:PF03061 AKAW2_40008S COG:H; EggNog:ENOG410QDKJ; InterPro:IPR005814,IPR015424,IPR015421,IPR015422; PFAM:PF00202; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0008483 - transaminase activity [Evidence IEA]; go_function: GO:0030170 - pyridoxal phosphate binding [Evidence IEA] AKAW2_40009S COG:M; EggNog:ENOG410PW7H; InterPro:IPR029044,IPR007577; PFAM:PF04488; TransMembrane:3 (o12-29i220-241o290-312i) AKAW2_40010A COG:G; EggNog:ENOG410PT43; InterPro:IPR002921,IPR029058; PFAM:PF01764; SECRETED:SignalP(1-21); go_process: GO:0006629 - lipid metabolic process [Evidence IEA] AKAW2_40011S COG:I; EggNog:ENOG410PMT4 AKAW2_40012A COG:E; EggNog:ENOG410PGJG; InterPro:IPR002034,IPR013785,IPR000891; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0046912 - transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer [Evidence IEA]; go_process: GO:0019752 - carboxylic acid metabolic process [Evidence IEA] AKAW2_40014A COG:P; EggNog:ENOG410PHB8; InterPro:IPR018028,IPR037060,IPR020835,IPR011614; go_function: GO:0004096 - catalase activity [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0006979 - response to oxidative stress [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_40016S COG:S; EggNog:ENOG410Q2BT; TransMembrane:7 (o12-29i50-73o88-106i127-153o159-178i190-208o228-247i) AKAW2_40015A COG:S; EggNog:ENOG410PVN3; InterPro:IPR036864,IPR021858,IPR001138; PFAM:PF11951; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_40017A COG:S; EggNog:ENOG410PTG5; SECRETED:SignalP(1-21) AKAW2_40018S COG:S; EggNog:ENOG410PTTE AKAW2_40019A COG:S; EggNog:ENOG410PK7P; InterPro:IPR001077,IPR036388,IPR016461,IPR029063, IPR036390; PFAM:PF00891; go_function: GO:0008168 - methyltransferase activity [Evidence IEA]; go_function: GO:0008171 - O-methyltransferase activity [Evidence IEA] AKAW2_40020A COG:S; EggNog:ENOG410PH44; InterPro:IPR029063,IPR016461,IPR001077; go_function: GO:0008168 - methyltransferase activity [Evidence IEA]; go_function: GO:0008171 - O-methyltransferase activity [Evidence IEA] AKAW2_40021S COG:V; EggNog:ENOG410PSG8; InterPro:IPR027461,IPR040921,IPR003507; PFAM:PF17676 AKAW2_40023A COG:Q; EggNog:ENOG410PRQ6; InterPro:IPR029063; PFAM:PF13489,PF13847,PF08241,PF13649 AKAW2_40025S CAZy:GH36; COG:G; EggNog:ENOG410PIUQ; InterPro:IPR000111,IPR002252,IPR031705,IPR031704, IPR017853,IPR013780,IPR013785,IPR038417; PFAM:PF02065,PF16874,PF16875; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_function: GO:0004557 - alpha-galactosidase activity [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA]; go_process: GO:0016052 - carbohydrate catabolic process [Evidence IEA] AKAW2_40026A COG:G; EggNog:ENOG410PJC8; InterPro:IPR036291,IPR001509; PFAM:PF04321,PF01370; go_function: GO:0003824 - catalytic activity [Evidence IEA] AKAW2_40027S COG:G; EggNog:ENOG410PGUV; InterPro:IPR016040,IPR036291,IPR020904; PFAM:PF04321,PF01073,PF16363,PF13460,PF02719, PF07993,PF01370; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA] AKAW2_40028S SECRETED:SignalP(1-20) AKAW2_40029S SECRETED:SignalP(1-20) AKAW2_40030S SECRETED:SignalP(1-20) AKAW2_40031S COG:S; EggNog:ENOG410PJUZ; InterPro:IPR016274,IPR033379,IPR000560,IPR029033; PFAM:PF00328; SECRETED:SignalP(1-23); go_function: GO:0016791 - phosphatase activity [Evidence IEA] AKAW2_40032A COG:S; EggNog:ENOG410PIKX; InterPro:IPR012292; PFAM:PF11563; go_function: GO:0019825 - oxygen binding [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA] AKAW2_40034S antiSMASH:Cluster_4.1 AKAW2_40033A COG:S; EggNog:ENOG410PRNH; InterPro:IPR011009; antiSMASH:Cluster_4.1 AKAW2_40035S COG:T; EggNog:ENOG410PV7A; InterPro:IPR008271,IPR002110,IPR036770,IPR020683, IPR000719,IPR011009; PFAM:PF12796,PF07714,PF00069,PF13637,PF13606; SMCOG1030:serine/threonine protein kinase; antiSMASH:Cluster_4.1; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_40036A COG:C; EggNog:ENOG410Q17S; InterPro:IPR006076,IPR036188; PFAM:PF01266; SMCOG1103:FAD dependent oxidoreductase; antiSMASH:Cluster_4.1; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_40037S COG:E; EggNog:ENOG410Q1U6; InterPro:IPR004841; PFAM:PF13520,PF00324; SMCOG1038:phenylalanine-specific permease; TransMembrane:12 (i46-68o74-105i125-146o152-173i185-204o220-240i274- 294o314-337i372-391o411-428i448-466o478-496i); antiSMASH:Cluster_4.1; go_component: GO:0016020 - membrane [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_40038S COG:E; EggNog:ENOG410PKRR; InterPro:IPR036412,IPR023198,IPR023214; PFAM:PF00702; antiSMASH:Cluster_4.1 AKAW2_40039A COG:K; EggNog:ENOG410PJAX; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; antiSMASH:Cluster_4.1; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_40040A COG:S; EggNog:ENOG410Q1T7; TransMembrane:5 (o20-41i53-76o96-114i126-148o204-222i); antiSMASH:Cluster_4.1 AKAW2_40041A COG:I; EggNog:ENOG410PJ8T; InterPro:IPR000873,IPR009081,IPR036736,IPR036291, IPR013120,IPR042099,IPR020845; PFAM:PF00501,PF00550,PF01370,PF07993; SMCOG1002:AMP-dependent synthetase and ligase; antiSMASH:Cluster_4.1 AKAW2_40042A COG:I; EggNog:ENOG410QE7Y; InterPro:IPR000073,IPR029058; MEROPS:MER0033244; PFAM:PF12697,PF07859,PF12146; antiSMASH:Cluster_4.1 AKAW2_40043S COG:S; EggNog:ENOG410PWIX; InterPro:IPR036291,IPR008030; PFAM:PF13460,PF05368; SMCOG1199:NmrA family protein; antiSMASH:Cluster_4.1 AKAW2_40044S COG:S; EggNog:ENOG410QDYX; InterPro:IPR025444; PFAM:PF13826; TransMembrane:1 (o44-72i); antiSMASH:Cluster_4.1 AKAW2_40045S COG:S; EggNog:ENOG410QDYX; InterPro:IPR036864,IPR021858,IPR001138; PFAM:PF00172; TransMembrane:1 (i172-193o); antiSMASH:Cluster_4.1; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_40046S COG:S; EggNog:ENOG410Q2TK; SECRETED:SignalP(1-21); antiSMASH:Cluster_4.1 AKAW2_40047A COG:I; EggNog:ENOG410PJ9B; InterPro:IPR000873,IPR020845,IPR009081,IPR006162, IPR036736,IPR042099,IPR023213,IPR001242; PFAM:PF00501,PF00668,PF00550; SMCOG1002:AMP-dependent synthetase and ligase; antiSMASH:Cluster_4.1; go_function: GO:0003824 - catalytic activity [Evidence IEA] AKAW2_40048S COG:S; EggNog:ENOG410PM5A; InterPro:IPR036188,IPR002938; PFAM:PF01494; SMCOG1087:hypothetical protein; antiSMASH:Cluster_4.1; go_function: GO:0071949 - FAD binding [Evidence IEA] AKAW2_40049A COG:S; EggNog:ENOG410PXFU; TransMembrane:1 (o36-54i); antiSMASH:Cluster_4.1 AKAW2_40050S COG:G; EggNog:ENOG410PMBP; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690,PF06609; SMCOG1005:Drug resistance transporter, EmrB/QacA; TransMembrane:14 (i152-177o189-208i220-239o245-266i278-302o308-328i348- 370o376-396i417-442o454-475i484-503o509-530i542-561o623- 641i); antiSMASH:Cluster_4.1; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_40051S COG:Q; EggNog:ENOG410PG8F; InterPro:IPR001128,IPR017972,IPR002401,IPR036396; PFAM:PF00067; SMCOG1034:cytochrome P450; TransMembrane:1 (i12-38o); antiSMASH:Cluster_4.1; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_40052S COG:S; EggNog:ENOG410PVT8; InterPro:IPR036291,IPR016040; PFAM:PF13460; SMCOG1199:NmrA family protein; antiSMASH:Cluster_4.1 AKAW2_40053S COG:S; EggNog:ENOG410PJ22; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; antiSMASH:Cluster_4.1; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_40054S COG:C,H; EggNog:ENOG410PPDP; InterPro:IPR036188,IPR002938; PFAM:PF01494; SECRETED:SignalP(1-18); SMCOG1087:hypothetical protein; antiSMASH:Cluster_4.1; go_function: GO:0071949 - FAD binding [Evidence IEA] AKAW2_40055S COG:S; EggNog:ENOG410PX17; InterPro:IPR036291,IPR016040; PFAM:PF13460,PF05368; SMCOG1199:NmrA family protein; antiSMASH:Cluster_4.1 AKAW2_40056A COG:S; EggNog:ENOG410PKSY; TransMembrane:5 (o94-113i125-145o165-185i220-241o261-284i); antiSMASH:Cluster_4.1 AKAW2_40057A COG:S; EggNog:ENOG410PKSY; TransMembrane:2 (i85-109o197-222i) AKAW2_40058S COG:S; EggNog:ENOG410PIUG AKAW2_40059A COG:S; EggNog:ENOG410PY9H; InterPro:IPR025568,IPR025951; PFAM:PF14232,PF14231 AKAW2_40060S COG:Q; EggNog:ENOG410PJ8G; InterPro:IPR002347,IPR036291,IPR020904; PFAM:PF00106,PF08643,PF13561,PF08659,PF01370; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_40061A COG:S; EggNog:ENOG410PSVC; InterPro:IPR022234; PFAM:PF12585 AKAW2_40062S COG:A; EggNog:ENOG410PIUX; InterPro:IPR036322,IPR027417,IPR015943,IPR001680, IPR019775,IPR020472,IPR017986; PFAM:PF00400; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_40063S COG:S; EggNog:ENOG410PKQS; InterPro:IPR032710 AKAW2_40064A COG:T; EggNog:ENOG410PJHG; InterPro:IPR004813; PFAM:PF03169; TransMembrane:12 (o96-114i126-147o201-221i259-277o340-359i413-433o499- 519i526-545o610-632i678-696o716-741i753-777o); go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_40065S CAZy:CBM43; CAZy:GH72; COG:S; EggNog:ENOG410PFK7; InterPro:IPR012946,IPR017853,IPR004886; PFAM:PF07983,PF03198; TransMembrane:1 (o407-435i) AKAW2_40066A COG:S; EggNog:ENOG410Q2GI; InterPro:IPR009197,IPR010799,IPR015995; MEROPS:MER0167712; PFAM:PF07364,PF07171 AKAW2_40067A COG:P; EggNog:ENOG410PFD7; InterPro:IPR006068,IPR018303,IPR023298,IPR023299, IPR001757,IPR004014,IPR036412,IPR006414,IPR008250, IPR023214; PFAM:PF00689,PF13246,PF00122,PF00702; TransMembrane:10 (i78-96o102-123i300-321o327-353i799-820o836-856i876- 897o930-948i977-996o1008-1032i); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0000166 - nucleotide binding [Evidence IEA]; go_function: GO:0019829 - ATPase-coupled cation transmembrane transporter activity [Evidence IEA]; go_process: GO:0006812 - cation transport [Evidence IEA] AKAW2_40068A COG:S; EggNog:ENOG410PWGQ; InterPro:IPR036005,IPR000994; MEROPS:MER0002038; PFAM:PF00557 AKAW2_40069S COG:S; EggNog:ENOG410PUXD; InterPro:IPR000073,IPR029058; PFAM:PF12697,PF12146,PF00561 AKAW2_40070S TransMembrane:4 (i33-61o81-103i115-138o150-172i) AKAW2_40071S COG:V; EggNog:ENOG410PWF3; InterPro:IPR012856,IPR012338,IPR001466,IPR027279; MEROPS:MER0000457; PFAM:PF07930,PF00144; go_function: GO:0004177 - aminopeptidase activity [Evidence IEA] AKAW2_40072S COG:P; EggNog:ENOG410PJ98; InterPro:IPR006068,IPR018303,IPR023298,IPR023299, IPR001757,IPR004014,IPR036412,IPR008250,IPR023214; PFAM:PF00689,PF13246,PF00122,PF00690,PF00702; TransMembrane:10 (i175-198o210-229i372-392o412-435i862-884o890-911i942- 962o1000-1017i1038-1060o1072-1089i); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0000166 - nucleotide binding [Evidence IEA] AKAW2_40073S COG:S; EggNog:ENOG410PKNA; InterPro:IPR018823,IPR018820; PFAM:PF13515,PF10337,PF10334; TransMembrane:11 (o45-75i82-102o153-172i184-201o221-244i595-619o631- 650i657-678o684-703i710-728o748-768i) AKAW2_40074S COG:S; EggNog:ENOG410PIA3; InterPro:IPR011118,IPR029058; PFAM:PF07519 AKAW2_40075A COG:G; EggNog:ENOG410PHNV; InterPro:IPR010720,IPR017853; PFAM:PF06964; go_function: GO:0046556 - alpha-L-arabinofuranosidase activity [Evidence IEA]; go_process: GO:0046373 - L-arabinose metabolic process [Evidence IEA] AKAW2_40076A COG:G; EggNog:ENOG410PHNV; InterPro:IPR017853 AKAW2_40077A COG:Q; EggNog:ENOG410PFN7; InterPro:IPR034001,IPR043926,IPR027417,IPR003593, IPR010929,IPR017871,IPR029481,IPR003439,IPR013525, IPR034003; PFAM:PF01061,PF00005,PF06422,PF14510; TransMembrane:13 (o480-501i513-534o554-578i590-610o616-639i725-746o1144- 1165i1177-1195o1215-1248i1260-1281o1287-1305i1317- 1336o1416-1434i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA]; go_function: GO:0042626 - ATPase-coupled transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_40078A COG:S; EggNog:ENOG410Q1MG; InterPro:IPR021054; PFAM:PF12296; SECRETED:SignalP(1-18) AKAW2_40079A COG:S; EggNog:ENOG410PVJT; InterPro:IPR010451,IPR023375; PFAM:PF06314; go_function: GO:0016829 - lyase activity [Evidence IEA] AKAW2_40080S COG:S; EggNog:ENOG410PWQA; InterPro:IPR000073,IPR029058,IPR000639; MEROPS:MER0026339; PFAM:PF12697,PF00561; go_function: GO:0003824 - catalytic activity [Evidence IEA] AKAW2_40081S COG:Q; EggNog:ENOG410PJDS; InterPro:IPR013154,IPR036291,IPR011032,IPR020843; PFAM:PF08240,PF13602; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_40082S COG:S; EggNog:ENOG410PVEF; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF04082; TransMembrane:1 (o538-557i); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_40083A CAZy:CE5; COG:S; EggNog:ENOG410PRAG; InterPro:IPR029058,IPR000675; PFAM:PF01083; SECRETED:SignalP(1-21); go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_40084A COG:I,J,T; EggNog:ENOG410PFMP; InterPro:IPR023631,IPR036928,IPR020556; PFAM:PF01425 AKAW2_40085S COG:Q; EggNog:ENOG410PH61; InterPro:IPR000399,IPR012001,IPR012000,IPR013154, IPR013149,IPR011766,IPR029061,IPR002328,IPR036291, IPR011032,IPR029035,IPR020843; PFAM:PF02776,PF08240,PF00205,PF00107; TransMembrane:1 (i446-468o); go_function: GO:0000287 - magnesium ion binding [Evidence IEA]; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0030976 - thiamine pyrophosphate binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_40086S COG:E,H; EggNog:ENOG410PUUP; InterPro:IPR012001,IPR012000,IPR011766,IPR029061, IPR029035,IPR012110; PFAM:PF02775,PF02776,PF00205; go_function: GO:0000287 - magnesium ion binding [Evidence IEA]; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0016831 - carboxy-lyase activity [Evidence IEA]; go_function: GO:0030976 - thiamine pyrophosphate binding [Evidence IEA] AKAW2_40087A TransMembrane:1 (n16-23c31/32o216-239i) AKAW2_40088A COG:S; EggNog:ENOG410PXHU; InterPro:IPR036236,IPR013087,IPR022755; PFAM:PF12874,PF12171 AKAW2_40089A COG:S; EggNog:ENOG410PPIM; InterPro:IPR005065,IPR041127,IPR029058; PFAM:PF12740; SECRETED:SignalP(1-18); go_function: GO:0003847 - 1-alkyl-2-acetylglycerophosphocholine esterase activity [Evidence IEA]; go_process: GO:0016042 - lipid catabolic process [Evidence IEA] AKAW2_40090A COG:C; EggNog:ENOG410PGED; InterPro:IPR011251,IPR016215,IPR036661; PFAM:PF00296; go_function: GO:0004497 - monooxygenase activity [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_40091A COG:S; EggNog:ENOG410PKP4; InterPro:IPR013154,IPR013149,IPR036291,IPR011032; PFAM:PF00107,PF08240; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_40092S COG:E; EggNog:ENOG410PFJ6; InterPro:IPR002293; PFAM:PF00324,PF13520; TransMembrane:12 (i40-60o72-93i114-140o152-173i185-203o232-251i271-293o323- 344i368-388o404-422i434-453o465-487i); go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_40093S COG:S; EggNog:ENOG410PK10; InterPro:IPR044053; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA] AKAW2_40094S COG:S; EggNog:ENOG410PHD7; InterPro:IPR011701,IPR036259; PFAM:PF07690,PF05978; TransMembrane:10 (i37-55o75-94i101-121o127-152i164-185o197-217i255-275o287- 307i319-339o359-379i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_40095S COG:S; EggNog:ENOG410PHD7; TransMembrane:1 (o24-42i) AKAW2_40096A COG:S; EggNog:ENOG410PFXD; InterPro:IPR010619,IPR024528; PFAM:PF06738,PF12821; TransMembrane:10 (i337-357o363-381i393-411o423-444i456-477o497-520i527- 545o551-568i580-605o625-651i) AKAW2_40098A COG:S; EggNog:ENOG410PR3D AKAW2_40099A COG:G; EggNog:ENOG410PITC; InterPro:IPR003710,IPR013752,IPR036291,IPR013332, IPR008927,IPR013328; PFAM:PF02558,PF08546; TransMembrane:1 (i12-30o); go_function: GO:0008677 - 2-dehydropantoate 2-reductase activity [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0015940 - pantothenate biosynthetic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_40100A COG:Q; EggNog:ENOG410PWSF; InterPro:IPR002925,IPR029058; PFAM:PF01738; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_40101A COG:Q; EggNog:ENOG410PKTH; InterPro:IPR036291,IPR002347; PFAM:PF08659,PF00106,PF13561; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_40102S COG:S; EggNog:ENOG410PJFZ; InterPro:IPR013897; PFAM:PF08588 AKAW2_40103A COG:Q; EggNog:ENOG410PG78; InterPro:IPR026992,IPR027443,IPR005123; PFAM:PF03171,PF14226; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_40104S COG:S; EggNog:ENOG410PRUM AKAW2_40105S CAZy:GH43; COG:G; EggNog:ENOG410PH4A; InterPro:IPR016840,IPR023296,IPR006710; PFAM:PF04616; SECRETED:SignalP(1-35); go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_function: GO:0046558 - arabinan endo-1,5-alpha-L-arabinosidase activity [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_40106S COG:S; EggNog:ENOG410PI00; InterPro:IPR036864,IPR021858,IPR001138; PFAM:PF00172; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_40107S COG:Q; EggNog:ENOG410PMB4; InterPro:IPR036291,IPR002347; PFAM:PF08659,PF00106,PF13561; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_40108S COG:S; EggNog:ENOG410QDUI; InterPro:IPR011990,IPR029058; PFAM:PF13374,PF13424; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_40109A COG:S; EggNog:ENOG410PZJX; antiSMASH:Cluster_4.2 AKAW2_40110S COG:I; EggNog:ENOG410PFXA; InterPro:IPR016035,IPR002642; PFAM:PF01735; SECRETED:SignalP(1-16); antiSMASH:Cluster_4.2; go_function: GO:0004620 - phospholipase activity [Evidence IEA]; go_process: GO:0009395 - phospholipid catabolic process [Evidence IEA] AKAW2_40111A SECRETED:SignalP(1-17); TransMembrane:1 (n4-12c17/18o33-55i); antiSMASH:Cluster_4.2 AKAW2_40112A COG:S; EggNog:ENOG410PZS7; antiSMASH:Cluster_4.2 AKAW2_40113A COG:I; EggNog:ENOG410Q2AH; InterPro:IPR036291,IPR026055,IPR013120; PFAM:PF07993; TransMembrane:1 (i12-30o); antiSMASH:Cluster_4.2; go_function: GO:0080019 - fatty-acyl-CoA reductase (alcohol-forming) activity [Evidence IEA] AKAW2_40114S COG:Q; EggNog:ENOG410PGYE; InterPro:IPR002402,IPR002974,IPR036396,IPR017972, IPR001128; PFAM:PF00067; SECRETED:SignalP(1-19); SMCOG1034:cytochrome P450; antiSMASH:Cluster_4.2; go_function: GO:0004497 - monooxygenase activity [Evidence IEA]; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0016712 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_40115S antiSMASH:Cluster_4.2 AKAW2_40116S COG:Q; EggNog:ENOG410QD7U; InterPro:IPR016036,IPR016035,IPR001227,IPR014043, IPR018201,IPR016039,IPR032821,IPR020807,IPR042104, IPR014030,IPR014031,IPR020841; PFAM:PF16197,PF14765,PF00109,PF02801,PF00698; SMCOG1022:Beta-ketoacyl synthase; antiSMASH:Cluster_4.2; go_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein] synthase activity [Evidence IEA]; go_function: GO:0016740 - transferase activity [Evidence IEA]; go_function: GO:0016746 - transferase activity, transferring acyl groups [Evidence IEA]; go_process: GO:0006633 - fatty acid biosynthetic process [Evidence IEA] AKAW2_40117S COG:Q; EggNog:ENOG410QD7U; InterPro:IPR009081,IPR029063,IPR036736,IPR036291, IPR011032,IPR013968,IPR020843; PFAM:PF00107,PF00106,PF13489,PF08659,PF13602; SMCOG1028:crotonyl-CoA reductase / alcohol dehydrogenase; antiSMASH:Cluster_4.2; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA] AKAW2_40118A COG:T; EggNog:ENOG410PM3Y; InterPro:IPR005178; PFAM:PF03619; TransMembrane:7 (o33-57i78-99o105-123i150-174o194-214i235-253o273-294i); antiSMASH:Cluster_4.2 AKAW2_40119A COG:S; EggNog:ENOG410PVJB; InterPro:IPR001138; TransMembrane:1 (n29-39c44/45o471-490i); antiSMASH:Cluster_4.2; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_40120S CAZy:AA7; COG:S; EggNog:ENOG410PJJU; InterPro:IPR006094,IPR036318,IPR016166,IPR012951; PFAM:PF08031,PF01565; SECRETED:SignalP(1-17); SMCOG1138:FAD linked oxidase domain protein; antiSMASH:Cluster_4.2; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_function: GO:0071949 - FAD binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_40121A COG:I; EggNog:ENOG410PHHR; InterPro:IPR008930,IPR032696; PFAM:PF13243,PF00432; antiSMASH:Cluster_4.2 AKAW2_40122A COG:I; EggNog:ENOG410PHHR; InterPro:IPR008930,IPR032697; PFAM:PF13249; SECRETED:SignalP(1-19); antiSMASH:Cluster_4.2 AKAW2_40123S COG:Q; EggNog:ENOG410PKBU; InterPro:IPR036396; TransMembrane:1 (i12-29o); antiSMASH:Cluster_4.2; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_40124A InterPro:IPR001810,IPR036047,IPR032675; PFAM:PF12937; antiSMASH:Cluster_4.2; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_40125S COG:S; EggNog:ENOG410PYKK; SECRETED:SignalP(1-26) AKAW2_40126A COG:S; EggNog:ENOG410PMDH; TransMembrane:4 (i49-70o76-96i157-173o179-201i) AKAW2_40127A COG:S; EggNog:ENOG410PMDH AKAW2_40128S COG:S; EggNog:ENOG410PSVQ; TransMembrane:1 (o213-234i) AKAW2_40129A COG:S; EggNog:ENOG410Q2Z1 AKAW2_40130A COG:S; EggNog:ENOG410QD8I; InterPro:IPR001810,IPR036047; PFAM:PF00646; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_40132A COG:K; EggNog:ENOG410Q1YA; InterPro:IPR007219; TransMembrane:1 (i451-469o); go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA] AKAW2_40133A COG:Q; EggNog:ENOG410PF88; InterPro:IPR000269,IPR015798,IPR036460; PFAM:PF01179; go_function: GO:0005507 - copper ion binding [Evidence IEA]; go_function: GO:0008131 - primary amine oxidase activity [Evidence IEA]; go_function: GO:0048038 - quinone binding [Evidence IEA]; go_process: GO:0009308 - amine metabolic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_40134A COG:S; EggNog:ENOG410PMHA; InterPro:IPR003609,IPR003378; TransMembrane:1 (i20-37o); go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0016757 - transferase activity, transferring glycosyl groups [Evidence IEA] AKAW2_40135A COG:S; EggNog:ENOG410PMTT; InterPro:IPR015915,IPR011043; PFAM:PF13854; antiSMASH:Cluster_4.3; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_40136S COG:S; EggNog:ENOG410Q1CA; InterPro:IPR000537; PFAM:PF01040; TransMembrane:7 (i114-133o139-156i168-185o191-211i232-250o262-282i294- 313o); antiSMASH:Cluster_4.3; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0016765 - transferase activity, transferring alkyl or aryl (other than methyl) groups [Evidence IEA] AKAW2_40137S COG:S; EggNog:ENOG410PX36; antiSMASH:Cluster_4.3 AKAW2_40138A COG:S; EggNog:ENOG410PXQZ; TransMembrane:6 (i12-30o60-82i94-117o137-155i175-192o212-235i); antiSMASH:Cluster_4.3 AKAW2_40139A COG:S; EggNog:ENOG410Q1TT; TransMembrane:2 (i140-164o184-201i); antiSMASH:Cluster_4.3 AKAW2_40140A antiSMASH:Cluster_4.3 AKAW2_40141S COG:I; EggNog:ENOG410PHJJ; InterPro:IPR029033; SECRETED:SignalP(1-28); antiSMASH:Cluster_4.3 AKAW2_40142S COG:G; EggNog:ENOG410PIQX; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; SMCOG1005:Drug resistance transporter, EmrB/QacA; TransMembrane:14 (i40-58o78-98i105-124o130-151i163-186o192-214i235-255o261- 277i297-319o331-354i361-384o390-412i424-450o506-526i); antiSMASH:Cluster_4.3; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_40143S COG:K; EggNog:ENOG410PTG7; InterPro:IPR035935,IPR009400; PFAM:PF06331; antiSMASH:Cluster_4.3; go_component: GO:0000439 - transcription factor TFIIH core complex [Evidence IEA]; go_process: GO:0006289 - nucleotide-excision repair [Evidence IEA]; go_process: GO:0006367 - transcription initiation from RNA polymerase II promoter [Evidence IEA] AKAW2_40144S antiSMASH:Cluster_4.3 AKAW2_40145A COG:S; EggNog:ENOG410PJXJ; InterPro:IPR007568; PFAM:PF04479; TransMembrane:7 (o39-57i64-84o96-117i138-158o170-196i258-274o294-314i); antiSMASH:Cluster_4.3; go_component: GO:0016021 - integral component of membrane [Evidence IEA] AKAW2_40146A COG:I; EggNog:ENOG410Q2RN; InterPro:IPR000873,IPR020845,IPR009081,IPR036736, IPR020806,IPR010071,IPR042099,IPR023213,IPR001242; PFAM:PF00501,PF00668,PF00550; SMCOG1002:AMP-dependent synthetase and ligase; TransMembrane:2 (o1773-1792i1799-1819o); antiSMASH:Cluster_4.3; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0031177 - phosphopantetheine binding [Evidence IEA] AKAW2_40147S antiSMASH:Cluster_4.3 AKAW2_40148S COG:Q; EggNog:ENOG410Q2N7; InterPro:IPR017871,IPR027417,IPR003593,IPR011527, IPR003439,IPR036640; PFAM:PF00005,PF00664; SMCOG1288:ABC transporter related protein; TransMembrane:12 (o32-50i70-87o99-118i266-289o309-329i382-401o407-426i487- 513o889-913i990-1011o1017-1037i1101-1122o); antiSMASH:Cluster_4.3; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA]; go_function: GO:0042626 - ATPase-coupled transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_40149S COG:T; EggNog:ENOG410PFAZ; InterPro:IPR000073,IPR029058; PFAM:PF12697,PF12146,PF00561; SMCOG1036:alpha/beta hydrolase fold protein; antiSMASH:Cluster_4.3 AKAW2_40150S COG:I; EggNog:ENOG410QDB3; InterPro:IPR032088,IPR003965,IPR041099,IPR039569, IPR001227,IPR014043,IPR002539,IPR040883,IPR016452, IPR016035,IPR029069,IPR013785,IPR013565; PFAM:PF17951,PF16073,PF13452,PF17828,PF01575, PF08354,PF00698; SMCOG1021:malonyl CoA-acyl carrier protein transacylase; antiSMASH:Cluster_4.3; go_component: GO:0005835 - fatty acid synthase complex [Evidence IEA]; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0004312 - fatty acid synthase activity [Evidence IEA]; go_function: GO:0004313 - [acyl-carrier-protein] S-acetyltransferase activity [Evidence IEA]; go_function: GO:0004314 - [acyl-carrier-protein] S-malonyltransferase activity [Evidence IEA]; go_function: GO:0004317 - 3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity [Evidence IEA]; go_function: GO:0004318 - enoyl-[acyl-carrier-protein] reductase (NADH) activity [Evidence IEA]; go_function: GO:0016740 - transferase activity [Evidence IEA]; go_process: GO:0006633 - fatty acid biosynthetic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_40151A COG:S; EggNog:ENOG410QE8P; InterPro:IPR029069; PFAM:PF13279; antiSMASH:Cluster_4.3 AKAW2_40152S COG:V; EggNog:ENOG410PJT2; InterPro:IPR001509,IPR036291; PFAM:PF01073,PF16363,PF07993,PF01370; go_function: GO:0003824 - catalytic activity [Evidence IEA] AKAW2_40153A COG:I; EggNog:ENOG410PJH0; InterPro:IPR042099,IPR000873,IPR025110; PFAM:PF00501,PF13193 AKAW2_40154A COG:C; EggNog:ENOG410PMQH AKAW2_40155S COG:S; EggNog:ENOG410Q18A; InterPro:IPR036188; TransMembrane:1 (o6-26i) AKAW2_40156S COG:S; EggNog:ENOG410Q18A; InterPro:IPR036188,IPR002938; go_function: GO:0071949 - FAD binding [Evidence IEA] AKAW2_40157A COG:S; EggNog:ENOG410PN5J; InterPro:IPR007568; PFAM:PF04479; TransMembrane:7 (o15-34i41-60o72-92i125-148o154-174i195-213o233-252i); go_component: GO:0016021 - integral component of membrane [Evidence IEA] AKAW2_40158S COG:Q; EggNog:ENOG410PI8J; InterPro:IPR001128,IPR017972,IPR002401,IPR036396; PFAM:PF00067; TransMembrane:2 (o20-40i227-248o); go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_40159S COG:G; EggNog:ENOG410PKMR; InterPro:IPR004104,IPR000683,IPR036291; PFAM:PF02894,PF01408; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA] AKAW2_40160S COG:E; EggNog:ENOG410PVTE; InterPro:IPR036038,IPR005786,IPR001544,IPR043131, IPR043132,IPR033939; PFAM:PF01063; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0004084 - branched-chain-amino-acid transaminase activity [Evidence IEA]; go_process: GO:0009081 - branched-chain amino acid metabolic process [Evidence IEA] AKAW2_40161A COG:Q; EggNog:ENOG410PV61; InterPro:IPR001128,IPR017972,IPR002401,IPR036396; PFAM:PF00067; TransMembrane:1 (o12-32i); go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_40162S COG:I; EggNog:ENOG410PUG3; InterPro:IPR016035,IPR009081,IPR041550,IPR016039, IPR036291,IPR018201,IPR026025,IPR014030,IPR014031, IPR040899; PFAM:PF18325,PF00109,PF02801,PF18314; go_component: GO:0005835 - fatty acid synthase complex [Evidence IEA]; go_function: GO:0004312 - fatty acid synthase activity [Evidence IEA]; go_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein] synthase activity [Evidence IEA]; go_function: GO:0004316 - 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity [Evidence IEA]; go_function: GO:0008897 - holo-[acyl-carrier-protein] synthase activity [Evidence IEA]; go_function: GO:0016746 - transferase activity, transferring acyl groups [Evidence IEA]; go_process: GO:0006633 - fatty acid biosynthetic process [Evidence IEA]; go_process: GO:0042759 - long-chain fatty acid biosynthetic process [Evidence IEA] AKAW2_40163A COG:U; EggNog:ENOG410PITD; InterPro:IPR022812,IPR027417,IPR001401,IPR000375, IPR030381,IPR020850; PFAM:PF00350,PF01031,PF01926; go_function: GO:0003924 - GTPase activity [Evidence IEA]; go_function: GO:0005525 - GTP binding [Evidence IEA] AKAW2_40164A COG:S; EggNog:ENOG410PNYQ; InterPro:IPR021139,IPR041966,IPR025605; PFAM:PF12872,PF01936 AKAW2_40165S COG:I; EggNog:ENOG410PKMS; InterPro:IPR001753,IPR029045,IPR014748; PFAM:PF00378,PF16113; go_function: GO:0003824 - catalytic activity [Evidence IEA] AKAW2_40166S CAZy:AA3; COG:E; EggNog:ENOG410PG0A; InterPro:IPR007867,IPR000172,IPR036188,IPR029058; PFAM:PF00732; TransMembrane:1 (o795-815i); go_function: GO:0016614 - oxidoreductase activity, acting on CH-OH group of donors [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_40167S InterPro:IPR007889; PFAM:PF05225; go_function: GO:0003677 - DNA binding [Evidence IEA] AKAW2_40168S InterPro:IPR004875; PFAM:PF03184; go_function: GO:0003676 - nucleic acid binding [Evidence IEA] AKAW2_40169A COG:S; EggNog:ENOG410PQHJ; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_40170A COG:G; EggNog:ENOG410PM2U; InterPro:IPR005828,IPR003663,IPR036259,IPR020846; PFAM:PF00083,PF07690; TransMembrane:12 (i12-35o55-75i82-99o105-129i141-162o174-195i264-282o302- 322i329-352o364-387i399-423o429-448i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_40171S COG:E; EggNog:ENOG410PVQJ; InterPro:IPR036526,IPR044149,IPR000132,IPR003010; PFAM:PF00795; SMCOG1294:Nitrilase/cyanide hydratase and apolipoprotein; antiSMASH:Cluster_4.4; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_process: GO:0006807 - nitrogen compound metabolic process [Evidence IEA] AKAW2_40172S antiSMASH:Cluster_4.4 AKAW2_40173S CAZy:GH1; COG:G; EggNog:ENOG410PFTX; InterPro:IPR017853,IPR001360; PFAM:PF00232; antiSMASH:Cluster_4.4; go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_40174A COG:I; EggNog:ENOG410PGIP; InterPro:IPR000873,IPR032387,IPR005914,IPR042099, IPR020845; PFAM:PF00501,PF16177; SMCOG1002:AMP-dependent synthetase and ligase; antiSMASH:Cluster_4.4; go_function: GO:0030729 - acetoacetate-CoA ligase activity [Evidence IEA]; go_process: GO:0006629 - lipid metabolic process [Evidence IEA] AKAW2_40175A CAZy:CE4; COG:G; EggNog:ENOG410PWU8; InterPro:IPR002509,IPR011330; PFAM:PF10096,PF01522; antiSMASH:Cluster_4.4; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0016810 - hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_40176S InterPro:IPR004360,IPR037523,IPR029068; PFAM:PF00903; antiSMASH:Cluster_4.4 AKAW2_40177A COG:I; EggNog:ENOG410PW3B; InterPro:IPR009081,IPR006162,IPR029063,IPR036736, IPR029058,IPR001031,IPR020802,IPR013217,IPR041068; PFAM:PF08242,PF13489,PF00550,PF00975,PF18558; antiSMASH:Cluster_4.4; go_function: GO:0016788 - hydrolase activity, acting on ester bonds [Evidence IEA]; go_process: GO:0009058 - biosynthetic process [Evidence IEA] AKAW2_40178A COG:I; EggNog:ENOG410PW3B; InterPro:IPR016036,IPR016035,IPR001227,IPR014043, IPR020807,IPR042104; PFAM:PF14765; antiSMASH:Cluster_4.4; go_function: GO:0016740 - transferase activity [Evidence IEA] AKAW2_40179A COG:I; EggNog:ENOG410PW3B; InterPro:IPR016035,IPR001227,IPR014043,IPR016039, IPR036291,IPR018201,IPR014030,IPR014031,IPR013968, IPR020841; PFAM:PF00109,PF00106,PF08659,PF02801; SMCOG1001:short-chain dehydrogenase/reductase SDR; antiSMASH:Cluster_4.4; go_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein] synthase activity [Evidence IEA]; go_function: GO:0016740 - transferase activity [Evidence IEA]; go_function: GO:0016746 - transferase activity, transferring acyl groups [Evidence IEA]; go_process: GO:0006633 - fatty acid biosynthetic process [Evidence IEA] AKAW2_40180S COG:L; EggNog:ENOG410PJ37; InterPro:IPR005123,IPR000868,IPR036380,IPR032854, IPR036282,IPR027450,IPR037151; PFAM:PF14497,PF13410,PF13532,PF00857; antiSMASH:Cluster_4.4; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0051213 - dioxygenase activity [Evidence IEA]; go_process: GO:0006281 - DNA repair [Evidence IEA]; go_process: GO:0006307 - DNA dealkylation involved in DNA repair [Evidence IEA]; go_process: GO:0035552 - oxidative single-stranded DNA demethylation [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_40181A antiSMASH:Cluster_4.4 AKAW2_40182A antiSMASH:Cluster_4.4 AKAW2_40183A COG:S; EggNog:ENOG410PR55; InterPro:IPR010730; PFAM:PF06985; antiSMASH:Cluster_4.4 AKAW2_40184S COG:S; EggNog:ENOG410PJVA; InterPro:IPR036188,IPR002938; PFAM:PF01494; SMCOG1087:hypothetical protein; antiSMASH:Cluster_4.4; go_function: GO:0071949 - FAD binding [Evidence IEA] AKAW2_40185S CAZy:CE12; COG:V; EggNog:ENOG410PNVV; InterPro:IPR013830,IPR036514,IPR037459; PFAM:PF13472; SECRETED:SignalP(1-17); antiSMASH:Cluster_4.4; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_40186A COG:I; EggNog:ENOG410PKH6; InterPro:IPR002921,IPR029058,IPR005592; PFAM:PF03893,PF01764; SECRETED:SignalP(1-19); antiSMASH:Cluster_4.4; go_process: GO:0006629 - lipid metabolic process [Evidence IEA]; go_process: GO:0016042 - lipid catabolic process [Evidence IEA] AKAW2_40187A COG:V; EggNog:ENOG410PW4U; InterPro:IPR001509,IPR036291; PFAM:PF04321,PF13460,PF07993,PF01370; go_function: GO:0003824 - catalytic activity [Evidence IEA] AKAW2_40188A COG:G,V; EggNog:ENOG410PVIP; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:11 (o33-51i72-91o97-117i129-148o160-180i192-214o263-287i299- 320o326-346i353-374o420-440i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_40189S COG:C; EggNog:ENOG410PFDH; InterPro:IPR036188,IPR002938; PFAM:PF01494,PF13450; SMCOG1087:hypothetical protein; antiSMASH:Cluster_4.5; go_function: GO:0071949 - FAD binding [Evidence IEA] AKAW2_40190A COG:S; EggNog:ENOG410PQYK; InterPro:IPR021858; PFAM:PF11951; antiSMASH:Cluster_4.5 AKAW2_40191A COG:Q; EggNog:ENOG410PK2Q; InterPro:IPR036291,IPR001509; PFAM:PF04321,PF16363,PF01370; SMCOG1010:NAD-dependent epimerase/dehydratase; antiSMASH:Cluster_4.5; go_function: GO:0003824 - catalytic activity [Evidence IEA] AKAW2_40192S COG:Q; EggNog:ENOG410PHWX; InterPro:IPR036291,IPR002347; PFAM:PF00106,PF13561; SMCOG1001:short-chain dehydrogenase/reductase SDR; antiSMASH:Cluster_4.5; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_40193A COG:G; EggNog:ENOG410Q2KJ; InterPro:IPR005829,IPR005828,IPR003663,IPR036259, IPR020846; PFAM:PF00083,PF07690; SMCOG1169:sugar transport protein; TransMembrane:12 (i48-68o104-124i131-148o160-179i191-213o225-244i312- 335o347-368i380-399o411-437i458-475o481-499i); antiSMASH:Cluster_4.5; go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_40194A COG:Q; EggNog:ENOG410QD82; InterPro:IPR009081,IPR036736,IPR036291,IPR020806, IPR013968; PFAM:PF00106,PF00550,PF08659; antiSMASH:Cluster_4.5; go_function: GO:0031177 - phosphopantetheine binding [Evidence IEA] AKAW2_40195A COG:Q; EggNog:ENOG410QD82; InterPro:IPR016036,IPR016035,IPR016039,IPR042104, IPR014030,IPR011032,IPR013154,IPR001227,IPR013217, IPR032821,IPR014031,IPR014043,IPR002328,IPR020807, IPR020843,IPR020841,IPR013149,IPR029063,IPR036291; PFAM:PF16197,PF00109,PF13489,PF02801,PF00698, PF13847,PF13649,PF14765,PF08242,PF08240,PF08241; SMCOG1093:Beta-ketoacyl synthase; antiSMASH:Cluster_4.5; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0016740 - transferase activity [Evidence IEA]; go_function: GO:0016746 - transferase activity, transferring acyl groups [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_40196S COG:G; EggNog:ENOG410PH0T; InterPro:IPR036259; SMCOG1005:Drug resistance transporter, EmrB/QacA; TransMembrane:5 (n4-13c18/19o42-63i70-92o104-127i134-158o206-226i); antiSMASH:Cluster_4.5 AKAW2_40197A InterPro:IPR043519; antiSMASH:Cluster_4.5 AKAW2_40198S COG:S; EggNog:ENOG410PXSU; antiSMASH:Cluster_4.5 AKAW2_40199S COG:S; EggNog:ENOG410Q06K; SECRETED:SignalP(1-18); antiSMASH:Cluster_4.5 AKAW2_40200S CAZy:CE10; COG:I; EggNog:ENOG410PRKF; InterPro:IPR029058,IPR013094; MEROPS:MER0003558; SMCOG1066:alpha/beta hydrolase domain-containing protein; antiSMASH:Cluster_4.5; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_40201A COG:S; EggNog:ENOG410PQ75; InterPro:IPR005821,IPR031846,IPR027359; TransMembrane:3 (i55-78o98-118i130-152o); antiSMASH:Cluster_4.5; go_component: GO:0005887 - integral component of plasma membrane [Evidence IEA]; go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0005216 - ion channel activity [Evidence IEA]; go_function: GO:0030171 - voltage-gated proton channel activity [Evidence IEA]; go_process: GO:0006811 - ion transport [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA]; go_process: GO:1902600 - proton transmembrane transport [Evidence IEA] AKAW2_40202A COG:C; EggNog:ENOG410PMK0; InterPro:IPR011251,IPR036661; PFAM:PF00296; SMCOG1083:oxidoreductase; antiSMASH:Cluster_4.5; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_40203A SECRETED:SignalP(1-18); antiSMASH:Cluster_4.5 AKAW2_40204S COG:E; EggNog:ENOG410PVY9; InterPro:IPR026956,IPR001608,IPR042208,IPR029066; PFAM:PF01168,PF14031; antiSMASH:Cluster_4.5 AKAW2_40205S COG:C,H; EggNog:ENOG410Q1FE; InterPro:IPR036188,IPR002938,IPR036249,IPR038220, IPR012941; PFAM:PF07976,PF01494; go_function: GO:0071949 - FAD binding [Evidence IEA] AKAW2_40206S COG:Q; EggNog:ENOG410PFP4; InterPro:IPR002042,IPR019842; PFAM:PF01014; go_function: GO:0004846 - urate oxidase activity [Evidence IEA]; go_process: GO:0006144 - purine nucleobase metabolic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_40207S COG:O; EggNog:ENOG410Q20D; InterPro:IPR001338; PFAM:PF01185; SECRETED:SignalP(1-23); go_component: GO:0009277 - fungal-type cell wall [Evidence IEA]; go_function: GO:0005199 - structural constituent of cell wall [Evidence IEA] AKAW2_40208S COG:J; EggNog:ENOG410PISF; InterPro:IPR012337,IPR032474,IPR036397,IPR036085, IPR003100,IPR003165; PFAM:PF02171,PF16486; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_40209S COG:O; EggNog:ENOG410Q20D; InterPro:IPR001338; SECRETED:SignalP(1-21); go_component: GO:0009277 - fungal-type cell wall [Evidence IEA]; go_function: GO:0005199 - structural constituent of cell wall [Evidence IEA] AKAW2_40210S COG:C; EggNog:ENOG410PFKP; InterPro:IPR013118,IPR036291,IPR000669,IPR013131, IPR008927,IPR013328; PFAM:PF01232,PF08125; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_40211A COG:Q; EggNog:ENOG410PNK2; InterPro:IPR036291,IPR002347; PFAM:PF08659,PF00106,PF13561; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_40212S COG:E; EggNog:ENOG410PJR2; InterPro:IPR005000,IPR015813,IPR040442; PFAM:PF03328; go_function: GO:0003824 - catalytic activity [Evidence IEA] AKAW2_40213A COG:Q; EggNog:ENOG410PQ2F; InterPro:IPR036291,IPR002347,IPR020904; PFAM:PF00106,PF13561; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_40214A COG:S; EggNog:ENOG410PH9C; InterPro:IPR019236; PFAM:PF09949; SECRETED:SignalP(1-22) AKAW2_40215S COG:S; EggNog:ENOG410PJV4; InterPro:IPR000073,IPR029058,IPR013595; MEROPS:MER0000441; PFAM:PF08386,PF00561 AKAW2_40217S COG:S; EggNog:ENOG410QEIF AKAW2_40216A COG:Q; EggNog:ENOG410Q2P6; InterPro:IPR034001,IPR043926,IPR027417,IPR003593, IPR010929,IPR017871,IPR034003,IPR003439,IPR013525; PFAM:PF01061,PF00005,PF06422; TransMembrane:9 (o446-469i490-515o527-551i558-577o663-685i1109-1126o1146- 1177i1197-1230o1343-1367i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA]; go_function: GO:0042626 - ATPase-coupled transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_40218S COG:Q; EggNog:ENOG410PNGT; InterPro:IPR036291,IPR002347; PFAM:PF08659,PF00106,PF13561; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_40219A COG:K; EggNog:ENOG410PJHT; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; TransMembrane:1 (o561-582i); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_40220S COG:I; EggNog:ENOG410PM3A; InterPro:IPR003703,IPR029069,IPR042171; PFAM:PF03061,PF13622; go_function: GO:0047617 - acyl-CoA hydrolase activity [Evidence IEA]; go_process: GO:0006637 - acyl-CoA metabolic process [Evidence IEA] AKAW2_40222A COG:Q; EggNog:ENOG410PU77; InterPro:IPR001128,IPR017972,IPR002401,IPR036396; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_40223A COG:Q; EggNog:ENOG410PU77; InterPro:IPR002402,IPR001128,IPR036396,IPR002974; TransMembrane:1 (o6-24i); go_function: GO:0004497 - monooxygenase activity [Evidence IEA]; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0016712 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_40224S COG:S; EggNog:ENOG410PWSY; InterPro:IPR000073,IPR029058; PFAM:PF12697,PF12146 AKAW2_40225S COG:T; EggNog:ENOG410PXR1; InterPro:IPR036457,IPR015655,IPR001932,IPR000222; PFAM:PF00481,PF13672; go_function: GO:0004722 - protein serine/threonine phosphatase activity [Evidence IEA]; go_function: GO:0016791 - phosphatase activity [Evidence IEA]; go_function: GO:0043169 - cation binding [Evidence IEA]; go_process: GO:0006470 - protein dephosphorylation [Evidence IEA] AKAW2_40226S COG:S; EggNog:ENOG410Q21D; InterPro:IPR019257,IPR017804,IPR017805; PFAM:PF10017; go_function: GO:0008168 - methyltransferase activity [Evidence IEA] AKAW2_40227A COG:P; EggNog:ENOG410PF7X; InterPro:IPR002524,IPR036837,IPR027470,IPR027469; PFAM:PF01545,PF16916; TransMembrane:6 (i139-160o166-187i208-228o248-267i287-305o311-328i); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0008324 - cation transmembrane transporter activity [Evidence IEA]; go_process: GO:0006812 - cation transport [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_40228A COG:S; EggNog:ENOG410PSHX; InterPro:IPR018392,IPR036779; PFAM:PF01476; SECRETED:SignalP(1-24); TransMembrane:1 (n8-19c24/25o231-249i) AKAW2_40229A COG:L; EggNog:ENOG410PFMH; InterPro:IPR012308,IPR012309,IPR036420,IPR029710, IPR036599,IPR001357,IPR000977,IPR016059,IPR012310, IPR012340,IPR044125; PFAM:PF04675,PF16589,PF01068,PF00533,PF04679, PF09414; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0003909 - DNA ligase activity [Evidence IEA]; go_function: GO:0003910 - DNA ligase (ATP) activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006281 - DNA repair [Evidence IEA]; go_process: GO:0006310 - DNA recombination [Evidence IEA]; go_process: GO:0051103 - DNA ligation involved in DNA repair [Evidence IEA]; go_process: GO:0071897 - DNA biosynthetic process [Evidence IEA] AKAW2_40230A COG:H; EggNog:ENOG410PUNI; InterPro:IPR005493,IPR036704; PFAM:PF03737 AKAW2_40231A BUSCO:EOG092619VG; COG:O; EggNog:ENOG410PISQ; InterPro:IPR001841,IPR024766,IPR013083; PFAM:PF13923,PF14634,PF00097,PF13639,PF12678; SECRETED:SignalP(1-22); TransMembrane:7 (n7-18c22/23o386-405i417-438o444-465i551-569o575-593i614- 633o639-655i); go_function: GO:0008270 - zinc ion binding [Evidence IEA] AKAW2_40232A COG:I; EggNog:ENOG410PFHQ; InterPro:IPR043573,IPR002013; PFAM:PF02383; go_function: GO:0042578 - phosphoric ester hydrolase activity [Evidence IEA]; go_function: GO:0043813 - phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity [Evidence IEA]; go_process: GO:0046856 - phosphatidylinositol dephosphorylation [Evidence IEA] AKAW2_40233A COG:S; EggNog:ENOG410PS59; InterPro:IPR022085; PFAM:PF12311 AKAW2_40234S COG:S; EggNog:ENOG410PYHI; InterPro:IPR016191; TransMembrane:1 (i67-88o); go_function: GO:0003723 - RNA binding [Evidence IEA]; go_function: GO:0004540 - ribonuclease activity [Evidence IEA] AKAW2_40235A COG:S; EggNog:ENOG410PIP3; InterPro:IPR011990,IPR019734; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_40236A COG:P; EggNog:ENOG410PFCK; InterPro:IPR003445,IPR015958,IPR004773; PFAM:PF02386; TransMembrane:8 (i32-53o87-112i419-443o488-514i550-572o617-634i674- 692o704-726i); go_component: GO:0005887 - integral component of plasma membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0008324 - cation transmembrane transporter activity [Evidence IEA]; go_function: GO:0015079 - potassium ion transmembrane transporter activity [Evidence IEA]; go_process: GO:0006812 - cation transport [Evidence IEA]; go_process: GO:0030007 - cellular potassium ion homeostasis [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA]; go_process: GO:0071805 - potassium ion transmembrane transport [Evidence IEA] AKAW2_40237A COG:K; EggNog:ENOG410PKPT; InterPro:IPR017930,IPR009057,IPR017877,IPR001005; PFAM:PF00249,PF13921 AKAW2_40238A COG:S; EggNog:ENOG410PM8W AKAW2_40239A COG:C,H; EggNog:ENOG410PNTM; InterPro:IPR017927,IPR039261; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_40240S COG:S; EggNog:ENOG410PU8W; TransMembrane:4 (i21-44o83-105i112-134o179-199i) AKAW2_40241S COG:S; EggNog:ENOG410PZN7 AKAW2_40242A COG:I; EggNog:ENOG410PG9B; InterPro:IPR002921,IPR029058; TransMembrane:1 (i21-40o); go_process: GO:0006629 - lipid metabolic process [Evidence IEA] AKAW2_40243A COG:I; EggNog:ENOG410PKYG; InterPro:IPR033177,IPR003817; PFAM:PF02666; SECRETED:SignalP(1-23); go_function: GO:0004609 - phosphatidylserine decarboxylase activity [Evidence IEA]; go_process: GO:0008654 - phospholipid biosynthetic process [Evidence IEA] AKAW2_40244A COG:Q; EggNog:ENOG410PNBN; InterPro:IPR002347,IPR036291,IPR020904; PFAM:PF00106,PF13561,PF08659,PF01370; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_40245A COG:E,G; EggNog:ENOG410PGHJ; InterPro:IPR004853; PFAM:PF03151; TransMembrane:10 (i12-33o45-64i84-109o115-134i141-162o168-188i200-219o234- 256i268-285o291-311i) AKAW2_40246A CAZy:GT32; COG:M; EggNog:ENOG410PR3G; InterPro:IPR029044,IPR007577; PFAM:PF04488; TransMembrane:1 (i24-42o) AKAW2_40247A COG:E,G; EggNog:ENOG410PIK3; InterPro:IPR000620; PFAM:PF00892; TransMembrane:10 (i72-90o110-128i140-159o165-186i193-211o227-247i259- 278o290-307i319-338o344-367i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA] AKAW2_40248A CAZy:GT25; COG:O; EggNog:ENOG410Q1W7; InterPro:IPR002654; TransMembrane:1 (i50-68o) AKAW2_40249A COG:O; EggNog:ENOG410Q1W7; InterPro:IPR000182,IPR016181; PFAM:PF13508,PF00583; go_function: GO:0008080 - N-acetyltransferase activity [Evidence IEA] AKAW2_40250A BUSCO:EOG09260B3H; COG:L; EggNog:ENOG410PGTD; InterPro:IPR006086,IPR006084,IPR006085,IPR019974, IPR001044,IPR036279,IPR008918,IPR029060; PFAM:PF00867,PF00752; go_component: GO:0005634 - nucleus [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0003697 - single-stranded DNA binding [Evidence IEA]; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0004518 - nuclease activity [Evidence IEA]; go_function: GO:0004519 - endonuclease activity [Evidence IEA]; go_function: GO:0016788 - hydrolase activity, acting on ester bonds [Evidence IEA]; go_process: GO:0006289 - nucleotide-excision repair [Evidence IEA] AKAW2_40251A COG:S; EggNog:ENOG410PS4R AKAW2_40252S COG:H; EggNog:ENOG410PIE4; InterPro:IPR006638,IPR010505,IPR007197,IPR013785, IPR013483,IPR000385; PFAM:PF06463,PF04055,PF13353; go_component: GO:0019008 - molybdopterin synthase complex [Evidence IEA]; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0046872 - metal ion binding [Evidence IEA]; go_function: GO:0051536 - iron-sulfur cluster binding [Evidence IEA]; go_function: GO:0051539 - 4 iron, 4 sulfur cluster binding [Evidence IEA]; go_process: GO:0006777 - Mo-molybdopterin cofactor biosynthetic process [Evidence IEA] AKAW2_40253S BUSCO:EOG09261BP0; COG:E; EggNog:ENOG410QE95; InterPro:IPR006855,IPR011190; PFAM:PF04768; go_function: GO:0004042 - acetyl-CoA:L-glutamate N-acetyltransferase activity [Evidence IEA] AKAW2_40254S COG:S; EggNog:ENOG410PFV0; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_40255A COG:S; EggNog:ENOG410Q024 AKAW2_40256A TransMembrane:1 (o28-55i) AKAW2_40257A COG:S; EggNog:ENOG410PQJN AKAW2_40258A CAZy:GH20; COG:G; EggNog:ENOG410PIDG; InterPro:IPR025705,IPR017853,IPR029018,IPR029019, IPR015883; PFAM:PF14845,PF00728; SECRETED:SignalP(1-20); go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_function: GO:0004563 - beta-N-acetylhexosaminidase activity [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_40259S COG:S; EggNog:ENOG410PQW2 AKAW2_40260A COG:O; EggNog:ENOG410PQT5; InterPro:IPR036249,IPR013766,IPR017937; PFAM:PF00085,PF13098 AKAW2_40261S COG:S; EggNog:ENOG410QEFX; InterPro:IPR029044,IPR030518; TransMembrane:2 (i45-62o82-102i); go_component: GO:0005794 - Golgi apparatus [Evidence IEA]; go_function: GO:0008375 - acetylglucosaminyltransferase activity [Evidence IEA]; go_process: GO:0006487 - protein N-linked glycosylation [Evidence IEA] AKAW2_40262S BUSCO:EOG09261HB6; COG:O; EggNog:ENOG410PHJR; InterPro:IPR000594,IPR035985; PFAM:PF00899; TransMembrane:1 (o16-37i); go_function: GO:0008641 - ubiquitin-like modifier activating enzyme activity [Evidence IEA] AKAW2_40263A CAZy:GT8; COG:G; EggNog:ENOG410PIS8; InterPro:IPR029044,IPR030518; go_component: GO:0005794 - Golgi apparatus [Evidence IEA]; go_function: GO:0008375 - acetylglucosaminyltransferase activity [Evidence IEA]; go_process: GO:0006487 - protein N-linked glycosylation [Evidence IEA] AKAW2_40264S COG:S; EggNog:ENOG410PPA0; InterPro:IPR033121,IPR021109; SECRETED:SignalP(1-22); TransMembrane:1 (n7-17c22/23o493-515i) AKAW2_40265S COG:T; EggNog:ENOG410PNM7; InterPro:IPR004843,IPR029052; PFAM:PF00149; TransMembrane:1 (i82-100o); go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_40266S COG:S; EggNog:ENOG410PZ38; InterPro:IPR007021,IPR012337,IPR008906; PFAM:PF04937,PF05699; go_function: GO:0046983 - protein dimerization activity [Evidence IEA] AKAW2_40267S COG:M; EggNog:ENOG410PMGY; InterPro:IPR002110,IPR020683,IPR036770; PFAM:PF12796,PF00023,PF13637,PF13857; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_40268S COG:B,D; EggNog:ENOG410PGYM; InterPro:IPR041188,IPR004875,IPR009057,IPR006600; PFAM:PF18107,PF03221,PF03184; go_function: GO:0003676 - nucleic acid binding [Evidence IEA] AKAW2_40269S COG:S; EggNog:ENOG410QEIF AKAW2_40270A COG:I; EggNog:ENOG410PIH4; InterPro:IPR000542,IPR042232,IPR042231,IPR039551; PFAM:PF00755; go_function: GO:0016746 - transferase activity, transferring acyl groups [Evidence IEA] AKAW2_40271S COG:I; EggNog:ENOG410PKIZ; InterPro:IPR008949; PFAM:PF00494; SECRETED:SignalP(1-28) AKAW2_40272A COG:Z; EggNog:ENOG410QEDU; InterPro:IPR011990; PFAM:PF07721,PF13374,PF13424,PF13176; TransMembrane:1 (o238-257i); go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_40273A COG:Z; EggNog:ENOG410QEDU; InterPro:IPR000845,IPR027417,IPR035994; PFAM:PF01048; SECRETED:SignalP(1-25); go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_process: GO:0009116 - nucleoside metabolic process [Evidence IEA] AKAW2_40274S COG:M; EggNog:ENOG410Q4IV; InterPro:IPR002110,IPR027417,IPR007111,IPR036770, IPR020683,IPR031359; PFAM:PF12796,PF00023,PF13637,PF17100,PF13606; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_40275S COG:A; EggNog:ENOG410PIUX; InterPro:IPR015943,IPR036322,IPR027417,IPR007111, IPR018391,IPR001680,IPR019775,IPR020472,IPR017986; PFAM:PF05729,PF00400,PF13191,PF08662; TransMembrane:1 (i637-661o); go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_40278S COG:J; EggNog:ENOG410PJCM; InterPro:IPR010117,IPR029062,IPR017926,IPR005801, IPR006805,IPR015890; MEROPS:MER0045095; PFAM:PF00425,PF04715,PF00117; go_process: GO:0009058 - biosynthetic process [Evidence IEA] AKAW2_40289A BUSCO:EOG092608WI; COG:L; EggNog:ENOG410PGCN; InterPro:IPR017961,IPR036420,IPR001126,IPR031991, IPR001357,IPR025527,IPR024728,IPR036775,IPR043502, IPR038401,IPR043128; PFAM:PF16589,PF00817,PF14377,PF11798,PF11799, PF16727; go_function: GO:0003684 - damaged DNA binding [Evidence IEA]; go_process: GO:0006281 - DNA repair [Evidence IEA] AKAW2_40290A CAZy:GH20; COG:G; EggNog:ENOG410PIDG; InterPro:IPR025705,IPR017853,IPR029018,IPR029019, IPR015883; PFAM:PF14845,PF00728; SECRETED:SignalP(1-20); go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_function: GO:0004563 - beta-N-acetylhexosaminidase activity [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_40291S COG:L; EggNog:ENOG410QDFS; InterPro:IPR014905,IPR001841,IPR027417,IPR000330, IPR038718,IPR001650,IPR014001,IPR013083; PFAM:PF00176,PF00271,PF08797; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_function: GO:0016818 - hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [Evidence IEA] AKAW2_40292S COG:Q; EggNog:ENOG410PV53; InterPro:IPR036188; PFAM:PF00743,PF13738,PF07992 AKAW2_40293A COG:S; EggNog:ENOG410PIYB; InterPro:IPR036322,IPR039328,IPR019775,IPR001680, IPR017986; PFAM:PF00400; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_40294S COG:I; EggNog:ENOG410PHQB; InterPro:IPR019819,IPR002018,IPR029058; MEROPS:MER0033188; PFAM:PF00135,PF07859; SECRETED:SignalP(1-43) AKAW2_40295A COG:M; EggNog:ENOG410PG6N; InterPro:IPR029044,IPR004835; PFAM:PF03142,PF13632,PF13641; TransMembrane:6 (o194-216i228-250o480-507i1047-1069o1075-1094i1101-1125o); go_function: GO:0004100 - chitin synthase activity [Evidence IEA]; go_function: GO:0016758 - transferase activity, transferring hexosyl groups [Evidence IEA] AKAW2_40297S COG:S; EggNog:ENOG410PJDC; InterPro:IPR000073,IPR029058; MEROPS:MER0000440; PFAM:PF08386,PF00561; TransMembrane:1 (o23-46i) AKAW2_40298A COG:L; EggNog:ENOG410PKF1; InterPro:IPR027450,IPR037151,IPR005123; PFAM:PF13532; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_40299A COG:E; EggNog:ENOG410Q2J6; InterPro:IPR004839,IPR004838,IPR000796,IPR015424, IPR015421,IPR015422; PFAM:PF00155; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0008483 - transaminase activity [Evidence IEA]; go_function: GO:0030170 - pyridoxal phosphate binding [Evidence IEA]; go_process: GO:0006520 - cellular amino acid metabolic process [Evidence IEA]; go_process: GO:0009058 - biosynthetic process [Evidence IEA] AKAW2_40300S COG:I; EggNog:ENOG410PMTM; InterPro:IPR002656; PFAM:PF01757; TransMembrane:10 (i98-117o137-160i190-209o244-263i275-295o315-334i373- 394o414-430i451-469o481-502i); go_function: GO:0016747 - transferase activity, transferring acyl groups other than amino-acyl groups [Evidence IEA] AKAW2_40302S SECRETED:SignalP(1-17) AKAW2_40303A COG:S; EggNog:ENOG410PW0T; InterPro:IPR000073,IPR029058; MEROPS:MER0037236; PFAM:PF12697,PF00561 AKAW2_40304S COG:G; EggNog:ENOG410PJK5; InterPro:IPR030395,IPR005000,IPR015813,IPR040442; PFAM:PF03328; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0008081 - phosphoric diester hydrolase activity [Evidence IEA]; go_process: GO:0006629 - lipid metabolic process [Evidence IEA] AKAW2_40306A COG:H; EggNog:ENOG410PUNI; InterPro:IPR005493,IPR036704; PFAM:PF03737 AKAW2_40307A COG:U; EggNog:ENOG410QDY5; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; SECRETED:SignalP(1-20); TransMembrane:12 (i43-65o85-106i113-132o138-164i176-197o203-223i276- 296o316-339i359-380o392-413i420-441o453-476i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_40308S COG:S; EggNog:ENOG410PNK9; InterPro:IPR007248; PFAM:PF04117; go_component: GO:0016021 - integral component of membrane [Evidence IEA] AKAW2_40309A COG:T; EggNog:ENOG410PWW7; InterPro:IPR000719,IPR011009; PFAM:PF07714,PF00069; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_40310A COG:S; EggNog:ENOG410PR5Z; InterPro:IPR023213,IPR010828; PFAM:PF07247 AKAW2_40311S COG:S; EggNog:ENOG410PUEV; InterPro:IPR036609,IPR004043; PFAM:PF03815; TransMembrane:7 (i110-129o292-325i346-363o383-400i421-439o451-474i495- 514o) AKAW2_40312A COG:E; EggNog:ENOG410PIX6; InterPro:IPR002293; PFAM:PF00324,PF13520; SMCOG1038:phenylalanine-specific permease; TransMembrane:13 (o30-53i65-87o107-126i133-151o157-178i185-208o228-252i264- 287o313-334i363-387o393-412i432-451o463-484i); antiSMASH:Cluster_4.6; go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_40313S COG:Q; EggNog:ENOG410Q18T; InterPro:IPR001613,IPR036188,IPR002937; PFAM:PF13450,PF01593; SECRETED:SignalP(1-24); antiSMASH:Cluster_4.6; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_40314A COG:Q; EggNog:ENOG410PJ01; InterPro:IPR001128,IPR017972,IPR002401,IPR036396; PFAM:PF00067; SMCOG1034:cytochrome P450; antiSMASH:Cluster_4.6; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_40315S COG:S; EggNog:ENOG410PRZG; InterPro:IPR024652,IPR008949; PFAM:PF06330; antiSMASH:Cluster_4.6; go_function: GO:0016838 - carbon-oxygen lyase activity, acting on phosphates [Evidence IEA] AKAW2_40316A COG:K; EggNog:ENOG410PKDN; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; antiSMASH:Cluster_4.6; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_40317S antiSMASH:Cluster_4.6 AKAW2_40318A COG:S; EggNog:ENOG410PJ95; InterPro:IPR043129 AKAW2_40320A InterPro:IPR043129 AKAW2_40321A InterPro:IPR043129 AKAW2_40323A COG:C; EggNog:ENOG410PJTX; InterPro:IPR034616,IPR029061,IPR001017; PFAM:PF00676; go_function: GO:0003826 - alpha-ketoacid dehydrogenase activity [Evidence IEA]; go_function: GO:0003863 - 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [Evidence IEA]; go_function: GO:0016624 - oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor [Evidence IEA]; go_process: GO:0009083 - branched-chain amino acid catabolic process [Evidence IEA] AKAW2_40324S COG:C; EggNog:ENOG410PHM6; InterPro:IPR036625,IPR000089,IPR001078,IPR004167, IPR023213,IPR011053; PFAM:PF00364,PF00198,PF02817; go_function: GO:0016746 - transferase activity, transferring acyl groups [Evidence IEA] AKAW2_40325A COG:B; EggNog:ENOG410PN9X; InterPro:IPR021162,IPR025789,IPR029063,IPR030445; PFAM:PF08123; go_component: GO:0005634 - nucleus [Evidence IEA]; go_function: GO:0018024 - histone-lysine N-methyltransferase activity [Evidence IEA]; go_function: GO:0031151 - histone methyltransferase activity (H3-K79 specific) [Evidence IEA]; go_function: GO:0031493 - nucleosomal histone binding [Evidence IEA]; go_process: GO:0000077 - DNA damage checkpoint [Evidence IEA]; go_process: GO:0006281 - DNA repair [Evidence IEA]; go_process: GO:0006348 - chromatin silencing at telomere [Evidence IEA]; go_process: GO:0034729 - histone H3-K79 methylation [Evidence IEA]; go_process: GO:0051726 - regulation of cell cycle [Evidence IEA] AKAW2_40326S COG:O,U; EggNog:ENOG410PRJJ; InterPro:IPR036286,IPR037730,IPR019533,IPR000223; MEROPS:MER0000598; PFAM:PF10502; go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0042720 - mitochondrial inner membrane peptidase complex [Evidence IEA]; go_function: GO:0008236 - serine-type peptidase activity [Evidence IEA]; go_process: GO:0006465 - signal peptide processing [Evidence IEA]; go_process: GO:0006508 - proteolysis [Evidence IEA]; go_process: GO:0006627 - protein processing involved in protein targeting to mitochondrion [Evidence IEA] AKAW2_40327A COG:T; EggNog:ENOG410PGVH; InterPro:IPR029217,IPR039486,IPR001849,IPR040345; PFAM:PF15407,PF15404 AKAW2_40328A COG:Z; EggNog:ENOG410PK2S; InterPro:IPR007259,IPR041470,IPR042241,IPR040457; PFAM:PF04130,PF17681; TransMembrane:1 (o557-581i); go_component: GO:0000922 - spindle pole [Evidence IEA]; go_component: GO:0005815 - microtubule organizing center [Evidence IEA]; go_function: GO:0043015 - gamma-tubulin binding [Evidence IEA]; go_process: GO:0000226 - microtubule cytoskeleton organization [Evidence IEA]; go_process: GO:0007020 - microtubule nucleation [Evidence IEA] AKAW2_40330A COG:S; EggNog:ENOG410PIZN; InterPro:IPR029191; PFAM:PF15456 AKAW2_40331A COG:S; EggNog:ENOG410PY96; InterPro:IPR003480,IPR023213; PFAM:PF02458; go_function: GO:0016747 - transferase activity, transferring acyl groups other than amino-acyl groups [Evidence IEA] AKAW2_40332A BUSCO:EOG092612MY; COG:T; EggNog:ENOG410PGF3; InterPro:IPR017850,IPR037675,IPR002591,IPR039524; TransMembrane:16 (o67-87i517-538o550-571i583-607o613-634i641-658o670- 689i710-733o745-764i785-805o849-866i873-889o895-915i945- 968o988-1013i1034-1054o); go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0016772 - transferase activity, transferring phosphorus-containing groups [Evidence IEA]; go_function: GO:0051377 - mannose-ethanolamine phosphotransferase activity [Evidence IEA]; go_process: GO:0006506 - GPI anchor biosynthetic process [Evidence IEA] AKAW2_40333A TransMembrane:1 (o50-68i) AKAW2_40334A COG:E; EggNog:ENOG410PF9H; InterPro:IPR000073,IPR008220,IPR029058; MEROPS:MER0044357; PFAM:PF00561; go_function: GO:0016747 - transferase activity, transferring acyl groups other than amino-acyl groups [Evidence IEA]; go_process: GO:0009058 - biosynthetic process [Evidence IEA] AKAW2_40335A COG:A; EggNog:ENOG410PNRE AKAW2_40336S COG:L; EggNog:ENOG410PHV4; InterPro:IPR036985,IPR038765,IPR018328,IPR018325, IPR018326,IPR018327,IPR042488,IPR004583; PFAM:PF10404,PF03835,PF10403,PF10405; go_component: GO:0005634 - nucleus [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0003684 - damaged DNA binding [Evidence IEA]; go_process: GO:0006289 - nucleotide-excision repair [Evidence IEA] AKAW2_40337S CAZy:CE10; COG:O; EggNog:ENOG410PJF7; InterPro:IPR001375,IPR029058; MEROPS:MER0000263; PFAM:PF12697,PF00326,PF00561; go_function: GO:0008236 - serine-type peptidase activity [Evidence IEA]; go_process: GO:0006508 - proteolysis [Evidence IEA] AKAW2_40338S COG:S; EggNog:ENOG410PP72; InterPro:IPR003807; PFAM:PF02656; TransMembrane:3 (i138-159o205-222i243-264o) AKAW2_40340A COG:S; EggNog:ENOG410Q01I AKAW2_40341S COG:S; EggNog:ENOG410PKBS; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; TransMembrane:1 (o586-604i); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_40342S COG:S; EggNog:ENOG410PJZM; InterPro:IPR011701,IPR036259; PFAM:PF07690,PF05978; TransMembrane:10 (i23-43o55-74i86-104o110-130i151-170o182-202i235-251o271- 291i303-323o413-433i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_40343S COG:S; EggNog:ENOG410PHUA; InterPro:IPR008929,IPR008397; PFAM:PF05426; SECRETED:SignalP(1-15); go_component: GO:0042597 - periplasmic space [Evidence IEA]; go_function: GO:0016829 - lyase activity [Evidence IEA] AKAW2_40344A BUSCO:EOG09260OLB; COG:Q; EggNog:ENOG410PIU0; InterPro:IPR017210,IPR019236; PFAM:PF09949 AKAW2_40345S COG:F; EggNog:ENOG410Q27B; InterPro:IPR031804,IPR015797,IPR000086; PFAM:PF15916,PF00293; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_40346A COG:U; EggNog:ENOG410QE2V; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:14 (i158-180o200-217i229-249o255-280i292-314o320-340i360- 381o387-408i429-453o465-482i494-511o523-544i556-578o598- 619i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_40347S COG:G; EggNog:ENOG410PFEN; InterPro:IPR005829,IPR005828,IPR003663,IPR036259, IPR020846; PFAM:PF00083,PF07690; TransMembrane:12 (i12-30o57-80i87-105o111-129i149-168o180-202i281-299o311- 332i339-362o374-393i405-427o433-454i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_40348A COG:S; EggNog:ENOG410PM59; InterPro:IPR036291,IPR015814,IPR006115,IPR008927, IPR013328; PFAM:PF03807,PF03446,PF09130; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0050661 - NADP binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_40349S COG:S; EggNog:ENOG410Q24I; InterPro:IPR008922,IPR002227; PFAM:PF00264; SECRETED:SignalP(1-19); go_function: GO:0016491 - oxidoreductase activity [Evidence IEA] AKAW2_40350A COG:S; EggNog:ENOG410Q2GC; InterPro:IPR017945,IPR006070; PFAM:PF01300; go_function: GO:0003725 - double-stranded RNA binding [Evidence IEA] AKAW2_40352A COG:S; EggNog:ENOG410PHCM; InterPro:IPR018392,IPR036779; PFAM:PF01476; SECRETED:SignalP(1-17) AKAW2_40353S COG:H; EggNog:ENOG410QE4C; InterPro:IPR002820,IPR023045,IPR036522; PFAM:PF01967; go_process: GO:0006777 - Mo-molybdopterin cofactor biosynthetic process [Evidence IEA] AKAW2_40354A COG:Q; EggNog:ENOG410PICP; InterPro:IPR014049,IPR005615,IPR037013,IPR016185, IPR014042,IPR014709,IPR004887; PFAM:PF03917,PF03199; go_function: GO:0004363 - glutathione synthase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016874 - ligase activity [Evidence IEA]; go_process: GO:0006750 - glutathione biosynthetic process [Evidence IEA] AKAW2_40355S COG:S; EggNog:ENOG410PJFF; InterPro:IPR025676; PFAM:PF14420 AKAW2_40356A COG:S; EggNog:ENOG410PWSK; InterPro:IPR025509; PFAM:PF14342; TransMembrane:4 (i91-110o116-140i152-171o191-212i) AKAW2_40357S COG:S; EggNog:ENOG410PWHH; InterPro:IPR011990,IPR019734,IPR013026; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_40358S COG:S; EggNog:ENOG410PJ07; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_40359S COG:P; EggNog:ENOG410PNV3; InterPro:IPR036874,IPR015892,IPR001765; PFAM:PF00484; go_function: GO:0004089 - carbonate dehydratase activity [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0015976 - carbon utilization [Evidence IEA] AKAW2_40360A CAZy:GH13; CAZy:GT5; COG:M; EggNog:ENOG410PF9V; InterPro:IPR013534,IPR006047,IPR017853; PFAM:PF08323,PF00128; SECRETED:SignalP(1-19); TransMembrane:13 (n3-14c19/20o1075-1097i1997-2019o2031-2048i2055-2077o2089- 2109i2121-2142o2172-2193i2213-2231o2246-2268i2277- 2298o2322-2342i2349-2372o2395-2415i); go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_40361S CAZy:GH13; COG:G; EggNog:ENOG410Q2HI; InterPro:IPR006047,IPR015340,IPR017853,IPR013780, IPR013777; PFAM:PF00128,PF09260; SECRETED:SignalP(1-25); TransMembrane:1 (n10-20c25/26o534-554i); go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0004556 - alpha-amylase activity [Evidence IEA]; go_function: GO:0005509 - calcium ion binding [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA]; go_process: GO:0016052 - carbohydrate catabolic process [Evidence IEA] AKAW2_40362S CAZy:GH13; COG:G; EggNog:ENOG410PINX; InterPro:IPR013776,IPR006047,IPR017853,IPR013780; PFAM:PF00128; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_function: GO:0005509 - calcium ion binding [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_40363A COG:S; EggNog:ENOG410PT9V; InterPro:IPR018466; PFAM:PF10342; SECRETED:SignalP(1-18) AKAW2_40364A COG:P; EggNog:ENOG410PFFZ; InterPro:IPR018028,IPR029062,IPR020835,IPR011614, IPR024708,IPR002226,IPR043156,IPR041399,IPR024712, IPR037060,IPR010582; PFAM:PF00199,PF06628; go_function: GO:0004096 - catalase activity [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0006979 - response to oxidative stress [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_40365S COG:C; EggNog:ENOG410PJYH; InterPro:IPR001670,IPR018211,IPR039697; PFAM:PF00465; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0046872 - metal ion binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_40366S COG:S; EggNog:ENOG410PSVV AKAW2_40367S COG:P; EggNog:ENOG410PG3H; InterPro:IPR026871,IPR018303,IPR023298,IPR023299, IPR001757,IPR023214,IPR006539,IPR036412,IPR008250, IPR032630,IPR032631; PFAM:PF13246,PF16209,PF00702,PF16212; TransMembrane:10 (i134-151o157-176i474-496o516-540i1092-1108o1120- 1141i1171-1190o1210-1229i1241-1260o1272-1292i); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0000166 - nucleotide binding [Evidence IEA]; go_function: GO:0000287 - magnesium ion binding [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0140326 - ATPase-coupled intramembrane lipid transporter activity [Evidence IEA]; go_process: GO:0015914 - phospholipid transport [Evidence IEA] AKAW2_40368A COG:G; EggNog:ENOG410PM1B; InterPro:IPR020846,IPR036259,IPR010573; PFAM:PF06609,PF07690; TransMembrane:14 (i29-47o67-85i97-116o122-146i153-176o188-207i227-248o254- 277i298-315o335-354i366-383o389-416i428-447o518-536i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_40369S COG:S; EggNog:ENOG410PPXJ; TransMembrane:7 (o22-46i58-79o104-126i138-158o178-201i213-235o255-278i) AKAW2_40371S COG:S; EggNog:ENOG410PITJ; InterPro:IPR036291 AKAW2_40372A COG:Q; EggNog:ENOG410PK71; InterPro:IPR001128,IPR017972,IPR002401,IPR036396; PFAM:PF00067; TransMembrane:1 (o16-37i); go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_40373S COG:S; EggNog:ENOG410PMUK; TransMembrane:7 (o6-30i42-64o84-109i121-140o160-185i197-217o237-256i) AKAW2_40374S COG:I; EggNog:ENOG410PV8S; InterPro:IPR002202,IPR023076,IPR023074,IPR009023, IPR004554,IPR009029; PFAM:PF00368; TransMembrane:1 (o342-362i); go_function: GO:0004420 - hydroxymethylglutaryl-CoA reductase (NADPH) activity [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_function: GO:0016616 - oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Evidence IEA]; go_process: GO:0008299 - isoprenoid biosynthetic process [Evidence IEA]; go_process: GO:0015936 - coenzyme A metabolic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_40375S COG:E; EggNog:ENOG410PJKZ; InterPro:IPR013057; PFAM:PF01490; TransMembrane:11 (i202-221o227-248i273-294o314-331i338-358o378-401i413- 436o456-481i502-520o526-548i560-584o) AKAW2_40376A CAZy:GH28; COG:G; EggNog:ENOG410PJ28; InterPro:IPR000743,IPR012334,IPR006626,IPR011050; PFAM:PF00295; SECRETED:SignalP(1-17); go_function: GO:0004650 - polygalacturonase activity [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_40377S COG:S; EggNog:ENOG410PN5J; InterPro:IPR007568; PFAM:PF04479; TransMembrane:7 (o14-33i40-59o79-104i116-141o153-176i197-217o232-252i); go_component: GO:0016021 - integral component of membrane [Evidence IEA] AKAW2_40378S COG:S; EggNog:ENOG410PN5J; InterPro:IPR007568; go_component: GO:0016021 - integral component of membrane [Evidence IEA] AKAW2_40379A COG:G; EggNog:ENOG410PMMT; InterPro:IPR013022,IPR036237; PFAM:PF01261 AKAW2_40380S CAZy:GH31; COG:G,M,O; EggNog:ENOG410PKMC; InterPro:IPR017853,IPR011013,IPR000322,IPR013780; PFAM:PF01055; SECRETED:SignalP(1-18); go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_function: GO:0030246 - carbohydrate binding [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_40381A COG:S; EggNog:ENOG410Q1GR; InterPro:IPR009571; PFAM:PF06687; TransMembrane:3 (o6-26i156-178o210-230i); go_component: GO:0005886 - plasma membrane [Evidence IEA] AKAW2_40382A COG:G; EggNog:ENOG410Q1FC; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i108-133o145-165i177-194o206-226i233-252o272-295i341- 360o380-399i420-442o448-473i480-502o514-536i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_40383S COG:S; EggNog:ENOG410PR5C; InterPro:IPR037523,IPR029068 AKAW2_40384S COG:G; EggNog:ENOG410PH5Q; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i113-137o143-166i178-198o204-222i243-263o275-294i315- 342o354-373i380-402o408-434i446-465o516-536i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_40385S COG:E; EggNog:ENOG410PKT4; InterPro:IPR002293,IPR004840; PFAM:PF13520,PF00324; TransMembrane:11 (o46-71i78-105o125-148i169-188o194-217i280-302o329- 349i379-401o407-430i450-472o484-504i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0006865 - amino acid transport [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_40386S COG:E; EggNog:ENOG410PUZE; InterPro:IPR004841; PFAM:PF13520,PF00324; TransMembrane:13 (o46-65i77-95o128-150i157-181o187-208i229-249o269-289i296- 316o322-341i370-389o395-420i441-464o476-496i); go_component: GO:0016020 - membrane [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_40387S COG:S; EggNog:ENOG410PNJE; InterPro:IPR021848; PFAM:PF11927 AKAW2_40388S COG:S; EggNog:ENOG410PHD3 AKAW2_40389A COG:S; EggNog:ENOG410Q1AV AKAW2_40390A COG:S; EggNog:ENOG410PQE1 AKAW2_40391S COG:S; EggNog:ENOG410PR8K; InterPro:IPR036249 AKAW2_40392A BUSCO:EOG092644Z6; COG:G; EggNog:ENOG410PGBP; InterPro:IPR011060,IPR026019,IPR013785,IPR000056; PFAM:PF00834; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0004750 - ribulose-phosphate 3-epimerase activity [Evidence IEA]; go_function: GO:0016857 - racemase and epimerase activity, acting on carbohydrates and derivatives [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA]; go_process: GO:0006098 - pentose-phosphate shunt [Evidence IEA] AKAW2_40393S COG:S; EggNog:ENOG410PHF5; InterPro:IPR013216,IPR029063; PFAM:PF08241; go_function: GO:0008168 - methyltransferase activity [Evidence IEA] AKAW2_40394S COG:A; EggNog:ENOG410PQNA; InterPro:IPR016654,IPR010920,IPR001163; PFAM:PF01423; go_process: GO:0006397 - mRNA processing [Evidence IEA] AKAW2_40395S BUSCO:EOG09261HQU; COG:L; EggNog:ENOG410PK6Y; InterPro:IPR036866,IPR011084; PFAM:PF07522 AKAW2_40396S COG:Q; EggNog:ENOG410PH46; InterPro:IPR001128,IPR017972,IPR002401,IPR036396; PFAM:PF00067; TransMembrane:1 (o6-24i); go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_40397A COG:T; EggNog:ENOG410PFPV; InterPro:IPR004813,IPR004648; PFAM:PF03169; TransMembrane:17 (i90-110o116-136i196-216o222-244i265-295o315-337i344- 366o412-434i466-485o491-508i515-534o540-559i571-594o648- 665i672-688o694-710i722-744o); go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_40398A COG:K; EggNog:ENOG410PHJM; InterPro:IPR036864,IPR001138; PFAM:PF00172; TransMembrane:3 (o239-256i277-300o312-332i); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_40399S COG:S; EggNog:ENOG410PRV4; InterPro:IPR007011; PFAM:PF04927 AKAW2_40400S COG:S; EggNog:ENOG410PMVZ; InterPro:IPR011057,IPR006913; PFAM:PF04828; go_function: GO:0016846 - carbon-sulfur lyase activity [Evidence IEA] AKAW2_40401S COG:C; EggNog:ENOG410Q1AI; InterPro:IPR002020,IPR016142,IPR036969,IPR016143; PFAM:PF00285; go_function: GO:0046912 - transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer [Evidence IEA] AKAW2_40402S COG:G; EggNog:ENOG410Q1AH; InterPro:IPR020846,IPR011701,IPR036259; TransMembrane:6 (i44-64o84-103i110-128o134-156i168-191o197-215i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_40403S COG:G; EggNog:ENOG410Q1AH; InterPro:IPR036259; TransMembrane:3 (o12-38i50-68o74-96i) AKAW2_40404S COG:S; EggNog:ENOG410PU56; InterPro:IPR036610,IPR008914,IPR035810; PFAM:PF01161; SECRETED:SignalP(1-21) AKAW2_40405S COG:K; EggNog:ENOG410PYCU; InterPro:IPR036864,IPR001138; PFAM:PF00172; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_40406A COG:S; EggNog:ENOG410Q1IR; InterPro:IPR005247,IPR036610,IPR008914; PFAM:PF01161; SECRETED:SignalP(1-22) AKAW2_40407S COG:P; EggNog:ENOG410PICK; InterPro:IPR024671,IPR036259; PFAM:PF11700; TransMembrane:13 (o38-61i118-137o149-168i175-198o273-293i305-329o349- 366i378-402o414-435i447-468o483-505i517-540o546-567i) AKAW2_40408A COG:T; EggNog:ENOG410PKAJ; InterPro:IPR035965,IPR000014,IPR000700; PFAM:PF13426 AKAW2_40409A COG:S; EggNog:ENOG410PZID; SECRETED:SignalP(1-18) AKAW2_40410A COG:E; EggNog:ENOG410PVVX; InterPro:IPR013057; PFAM:PF01490; TransMembrane:11 (i35-55o61-79i109-133o139-159i166-188o208-232i253-275o295- 318i339-361o367-388i400-425o) AKAW2_40411A COG:S; EggNog:ENOG410PX4D AKAW2_40412A COG:S; EggNog:ENOG410PN8D AKAW2_40413S COG:G,M; EggNog:ENOG410PP90; InterPro:IPR036291,IPR008030; PFAM:PF13460,PF05368 AKAW2_40414A COG:I; EggNog:ENOG410PIM1; InterPro:IPR006091,IPR009075,IPR041504,IPR009100, IPR036250; PFAM:PF02770,PF18158,PF00441; go_function: GO:0016627 - oxidoreductase activity, acting on the CH-CH group of donors [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_40415S COG:S; EggNog:ENOG410PKXF; InterPro:IPR004843,IPR029052; PFAM:PF00149,PF12850; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_40416A COG:T; EggNog:ENOG410PKMI; InterPro:IPR002018,IPR029058; MEROPS:MER0033198; PFAM:PF00135; TransMembrane:1 (i7-25o) AKAW2_40417S COG:O; EggNog:ENOG410PK08; InterPro:IPR023828,IPR000209,IPR034193,IPR010259, IPR023827,IPR022398,IPR015500,IPR036852,IPR037045; MEROPS:MER0000344; PFAM:PF00082,PF05922; SECRETED:SignalP(1-20); go_function: GO:0004252 - serine-type endopeptidase activity [Evidence IEA]; go_function: GO:0008236 - serine-type peptidase activity [Evidence IEA]; go_process: GO:0006508 - proteolysis [Evidence IEA] AKAW2_40418S COG:G; EggNog:ENOG410Q1QE; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i56-75o95-113i125-144o150-169i181-207o213-233i283- 306o326-344i365-387o393-412i424-449o461-480i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_40419S COG:S; EggNog:ENOG410Q20G; TransMembrane:1 (i7-26o) AKAW2_40420S COG:G; EggNog:ENOG410PG63; InterPro:IPR036259; TransMembrane:2 (i53-73o93-113i) AKAW2_40421S COG:G; EggNog:ENOG410PG63; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:8 (i49-69o81-111i158-182o194-215i236-255o261-282i294- 314o326-348i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_40422S COG:G; EggNog:ENOG410PUJ2; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i54-73o93-111i123-139o151-172i184-203o215-241i280- 303o323-347i368-387o399-421i428-450o462-483i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_40423A COG:S; EggNog:ENOG410PFV0; InterPro:IPR001138,IPR007219,IPR036864; PFAM:PF04082; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_40424S COG:E; EggNog:ENOG410PHSD; InterPro:IPR005814,IPR015424,IPR015421,IPR015422; PFAM:PF00202; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0008483 - transaminase activity [Evidence IEA]; go_function: GO:0030170 - pyridoxal phosphate binding [Evidence IEA] AKAW2_40425A COG:K; EggNog:ENOG410PI70; InterPro:IPR009060,IPR041800,IPR003892; PFAM:PF02845; go_function: GO:0005515 - protein binding [Evidence IEA]; go_function: GO:0043130 - ubiquitin binding [Evidence IEA] AKAW2_40426S COG:S; EggNog:ENOG410PVT8; InterPro:IPR036291,IPR016040; PFAM:PF13460; TransMembrane:1 (o62-83i) AKAW2_40427S COG:C; EggNog:ENOG410PFVP; InterPro:IPR001030,IPR018136,IPR015932,IPR036008, IPR015931,IPR006248,IPR015928,IPR000573; PFAM:PF00694,PF00330; go_function: GO:0003994 - aconitate hydratase activity [Evidence IEA]; go_function: GO:0051539 - 4 iron, 4 sulfur cluster binding [Evidence IEA]; go_process: GO:0006099 - tricarboxylic acid cycle [Evidence IEA] AKAW2_40428A COG:S; EggNog:ENOG410PHP8; InterPro:IPR027450,IPR032852; PFAM:PF13532; go_process: GO:0006281 - DNA repair [Evidence IEA] AKAW2_40429A COG:C; EggNog:ENOG410PFMM; InterPro:IPR006140,IPR036291,IPR006139,IPR029753, IPR029752; PFAM:PF00389,PF02826; go_function: GO:0016616 - oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Evidence IEA]; go_function: GO:0051287 - NAD binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_40430S COG:Q; EggNog:ENOG410PIJ6; InterPro:IPR013154,IPR013149,IPR002328,IPR036291, IPR011032,IPR020843; PFAM:PF00107,PF08240; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_40431S COG:S; EggNog:ENOG410Q19E; InterPro:IPR024206,IPR009101; PFAM:PF11410; SECRETED:SignalP(1-17) AKAW2_40432A COG:S; EggNog:ENOG410PT6M AKAW2_40433A COG:S; EggNog:ENOG410PKQH; InterPro:IPR018535; PFAM:PF09362 AKAW2_40435S COG:E; EggNog:ENOG410PG14; InterPro:IPR002293; PFAM:PF00324,PF13520; TransMembrane:12 (i45-64o76-98i126-149o169-189i201-223o243-266i278-300o329- 352i383-401o407-432i444-468o480-499i); go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_40437A InterPro:IPR000210,IPR011333; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_40438A COG:I,J,T; EggNog:ENOG410PH99; InterPro:IPR023631,IPR036928,IPR020556; PFAM:PF01425 AKAW2_40440S COG:S; EggNog:ENOG410PTVY; InterPro:IPR036864,IPR021858,IPR001138; PFAM:PF00172; TransMembrane:1 (i186-203o); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_40441S COG:I; EggNog:ENOG410PN57; InterPro:IPR014710,IPR011051,IPR003829; PFAM:PF02678; TransMembrane:1 (i55-77o) AKAW2_40442A COG:T; EggNog:ENOG410PPC2; InterPro:IPR000719,IPR011009; PFAM:PF00069; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_40443S COG:E; EggNog:ENOG410PH5F; InterPro:IPR036152,IPR006034,IPR002110,IPR041725, IPR040919,IPR036770,IPR027474,IPR027473,IPR020683, IPR037152; PFAM:PF13857,PF00023,PF00710,PF13637,PF17763, PF13606,PF12796; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_40444S COG:K; EggNog:ENOG410PHQK; InterPro:IPR036291,IPR008030; PFAM:PF05368 AKAW2_40445S COG:L; EggNog:ENOG410PQDW; InterPro:IPR037231,IPR002164; PFAM:PF00956; go_component: GO:0005634 - nucleus [Evidence IEA]; go_process: GO:0006334 - nucleosome assembly [Evidence IEA] AKAW2_40446A COG:U; EggNog:ENOG410PIQ4; InterPro:IPR010989,IPR000727,IPR015260; PFAM:PF09177; go_component: GO:0016020 - membrane [Evidence IEA]; go_process: GO:0016192 - vesicle-mediated transport [Evidence IEA]; go_process: GO:0048193 - Golgi vesicle transport [Evidence IEA] AKAW2_40447A COG:S; EggNog:ENOG410Q1WR AKAW2_40448S COG:S; EggNog:ENOG410PFBR; InterPro:IPR025714; PFAM:PF13679; TransMembrane:1 (o584-602i) AKAW2_40449A COG:S; EggNog:ENOG410PXY3; InterPro:IPR000182,IPR016181; PFAM:PF13673,PF13508,PF00583; go_function: GO:0008080 - N-acetyltransferase activity [Evidence IEA] AKAW2_40450A COG:Q; EggNog:ENOG410PW1V; InterPro:IPR002401,IPR001433,IPR036396,IPR017927, IPR003097,IPR017972,IPR023173,IPR029039,IPR001128, IPR008254,IPR017938,IPR039261,IPR023206; PFAM:PF00175,PF00067,PF00258,PF00667; TransMembrane:3 (o823-840i877-895o915-931i); go_function: GO:0003958 - NADPH-hemoprotein reductase activity [Evidence IEA]; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0010181 - FMN binding [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_function: GO:0070330 - aromatase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_40451A COG:S; EggNog:ENOG410Q2NJ; TransMembrane:5 (i26-47o53-75i96-118o130-151i216-236o) AKAW2_40452S COG:Q; EggNog:ENOG410Q2A7; InterPro:IPR013525,IPR017871,IPR027417,IPR010929, IPR029481,IPR003439,IPR034001; PFAM:PF01061,PF00005,PF06422,PF14510; TransMembrane:6 (i482-502o514-535i564-582o588-610i622-645o728-748i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA]; go_function: GO:0042626 - ATPase-coupled transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_40453S COG:Q; EggNog:ENOG410Q2A7; InterPro:IPR043926,IPR027417,IPR013525; PFAM:PF01061; TransMembrane:7 (o280-302i314-335o355-379i400-424o430-449i456-475o552- 573i); go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0042626 - ATPase-coupled transmembrane transporter activity [Evidence IEA] AKAW2_40454S COG:S; EggNog:ENOG410PUW0; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF04082; SECRETED:SignalP(1-17); TransMembrane:1 (o540-563i); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_40455S CAZy:GT1; COG:C,G; EggNog:ENOG410PV20; InterPro:IPR004276; PFAM:PF03033; go_function: GO:0016758 - transferase activity, transferring hexosyl groups [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA]; go_process: GO:0030259 - lipid glycosylation [Evidence IEA] AKAW2_40456S COG:S; EggNog:ENOG410PJ9N; InterPro:IPR029058 AKAW2_40457S COG:K; EggNog:ENOG410PFXW; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172; TransMembrane:1 (o539-562i); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_40458A COG:Q; EggNog:ENOG410PM5R; InterPro:IPR036291,IPR002347; PFAM:PF00106,PF13561; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_40459A COG:P; EggNog:ENOG410PHEQ; InterPro:IPR013099,IPR003280; PFAM:PF07885; TransMembrane:9 (i37-65o93-114i121-148o160-184i204-226o261-283i372- 394o400-418i430-447o); go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0005267 - potassium channel activity [Evidence IEA]; go_process: GO:0071805 - potassium ion transmembrane transport [Evidence IEA] AKAW2_40460A COG:S; EggNog:ENOG410PXIV; TransMembrane:7 (o27-51i63-83o103-125i137-160o180-206i218-241o261-280i) AKAW2_40461A COG:S; EggNog:ENOG410Q0A3; InterPro:IPR007325,IPR037175; PFAM:PF04199; go_function: GO:0004061 - arylformamidase activity [Evidence IEA]; go_process: GO:0019441 - tryptophan catabolic process to kynurenine [Evidence IEA] AKAW2_40462S COG:G; EggNog:ENOG410PM2U; InterPro:IPR005829,IPR005828,IPR003663,IPR036259, IPR020846; PFAM:PF00083,PF07690; TransMembrane:10 (i12-33o70-90i97-120o140-160i172-192o204-227i300-318o338- 358i370-391o403-425i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_40463S COG:S; EggNog:ENOG410PJI3 AKAW2_40464A COG:S; EggNog:ENOG410PFXD; InterPro:IPR024528,IPR010619; PFAM:PF06738,PF12821; TransMembrane:10 (i523-543o549-567i574-595o607-631i643-666o686-704i711- 728o734-754i766-791o834-859i) AKAW2_40465A COG:S; EggNog:ENOG410PN5I; InterPro:IPR013218; PFAM:PF08202; go_component: GO:0000444 - MIS12/MIND type complex [Evidence IEA]; go_process: GO:0007059 - chromosome segregation [Evidence IEA]; go_process: GO:0051301 - cell division [Evidence IEA] AKAW2_40466A COG:I; EggNog:ENOG410PFCS; InterPro:IPR003817,IPR011992,IPR033177,IPR035892, IPR033179,IPR000008,IPR002048,IPR018247; PFAM:PF00168,PF02666; go_function: GO:0004609 - phosphatidylserine decarboxylase activity [Evidence IEA]; go_function: GO:0005509 - calcium ion binding [Evidence IEA]; go_process: GO:0008654 - phospholipid biosynthetic process [Evidence IEA] AKAW2_40467S COG:S; EggNog:ENOG410PMDH; TransMembrane:4 (i156-177o183-203i263-280o286-308i) AKAW2_40468A COG:G; EggNog:ENOG410PFZ3; InterPro:IPR005829,IPR005828,IPR003663,IPR036259, IPR020846; PFAM:PF00083,PF07690; TransMembrane:12 (i12-31o67-87i99-123o129-146i158-180o186-207i291-315o321- 344i356-377o383-405i417-438o450-467i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_40469S COG:K; EggNog:ENOG410PGXB; InterPro:IPR000719,IPR011009,IPR008271; PFAM:PF07714,PF00069; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_40470A BUSCO:EOG09262E7W; COG:S; EggNog:ENOG410PKV7; InterPro:IPR040204,IPR003126; PFAM:PF02207; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_function: GO:0061630 - ubiquitin protein ligase activity [Evidence IEA] AKAW2_40471S COG:L; EggNog:ENOG410PFZA; InterPro:IPR033762,IPR027417,IPR001208,IPR041562, IPR027925,IPR008045,IPR031327,IPR012340,IPR018525; PFAM:PF00493,PF17855,PF17207,PF07728,PF12619, PF14551; go_component: GO:0005634 - nucleus [Evidence IEA]; go_component: GO:0042555 - MCM complex [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006260 - DNA replication [Evidence IEA]; go_process: GO:0006270 - DNA replication initiation [Evidence IEA]; go_process: GO:0032508 - DNA duplex unwinding [Evidence IEA]; go_process: GO:1905775 - negative regulation of DNA helicase activity [Evidence IEA] AKAW2_40472A COG:S; EggNog:ENOG410PN5G; InterPro:IPR013226; PFAM:PF08316 AKAW2_40473S BUSCO:EOG09265KF9; COG:K; EggNog:ENOG410PSFP; InterPro:IPR038089,IPR008831; PFAM:PF05669; go_component: GO:0016592 - mediator complex [Evidence IEA]; go_function: GO:0003712 - transcription coregulator activity [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_40474S COG:S; EggNog:ENOG410QDJJ; InterPro:IPR039786; go_process: GO:0072659 - protein localization to plasma membrane [Evidence IEA] AKAW2_40475A COG:G; EggNog:ENOG410PMHB; InterPro:IPR030294,IPR002472,IPR029058; PFAM:PF02089; SECRETED:SignalP(1-19); go_function: GO:0008474 - palmitoyl-(protein) hydrolase activity [Evidence IEA]; go_function: GO:0098599 - palmitoyl hydrolase activity [Evidence IEA]; go_process: GO:0002084 - protein depalmitoylation [Evidence IEA] AKAW2_40476A COG:S; EggNog:ENOG410Q1GQ AKAW2_40477S COG:S; EggNog:ENOG410PPUY; InterPro:IPR013087; TransMembrane:1 (o25-42i) AKAW2_40478A TransMembrane:1 (o32-51i) AKAW2_40479A COG:F; EggNog:ENOG410PNHT; InterPro:IPR027417,IPR013641; PFAM:PF08433 AKAW2_40480A COG:S; EggNog:ENOG410PNHF; InterPro:IPR029063,IPR019410,IPR025784; PFAM:PF10294 AKAW2_40481S COG:S; EggNog:ENOG410Q0VM AKAW2_40482A COG:S; EggNog:ENOG410Q2S1 AKAW2_40484A COG:D,O; EggNog:ENOG410PGJT; InterPro:IPR029030; MEROPS:MER0114503; PFAM:PF00656 AKAW2_40485S COG:S; EggNog:ENOG410PP0Y; InterPro:IPR001810,IPR036047; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_40489A COG:C,H; EggNog:ENOG410PKIF; InterPro:IPR036188,IPR002938; PFAM:PF01494; SECRETED:SignalP(1-20); go_function: GO:0071949 - FAD binding [Evidence IEA] AKAW2_40490A COG:S; EggNog:ENOG410PXTB; InterPro:IPR022185; PFAM:PF12505; TransMembrane:1 (i64-88o) AKAW2_40491S COG:S; EggNog:ENOG410Q2VJ; InterPro:IPR018713; PFAM:PF09995 AKAW2_40492A COG:S; EggNog:ENOG410Q29G; SECRETED:SignalP(1-21) AKAW2_40493A BUSCO:EOG09262PPU; COG:T; EggNog:ENOG410QE91; InterPro:IPR004148,IPR027267,IPR036028,IPR001452; PFAM:PF03114,PF00018,PF14604,PF07653; go_component: GO:0005737 - cytoplasm [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_40494S COG:E; EggNog:ENOG410PFTC; InterPro:IPR010240,IPR015424,IPR000192,IPR020578, IPR015421,IPR015422; PFAM:PF00266; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0030170 - pyridoxal phosphate binding [Evidence IEA]; go_function: GO:0031071 - cysteine desulfurase activity [Evidence IEA]; go_process: GO:0044571 - [2Fe-2S] cluster assembly [Evidence IEA] AKAW2_40495S COG:E; EggNog:ENOG410PFRQ; InterPro:IPR037217,IPR000898; PFAM:PF01231; go_function: GO:0020037 - heme binding [Evidence IEA]; go_function: GO:0046872 - metal ion binding [Evidence IEA]; go_process: GO:0019441 - tryptophan catabolic process to kynurenine [Evidence IEA] AKAW2_40497S COG:S; EggNog:ENOG410PPJ9; InterPro:IPR036629 AKAW2_40496A COG:T; EggNog:ENOG410PFPF; InterPro:IPR000719,IPR011009; PFAM:PF07714,PF00069; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_40499S COG:S; EggNog:ENOG410Q1FN; SECRETED:SignalP(1-19) AKAW2_40500A COG:O,U; EggNog:ENOG410PR05; InterPro:IPR017916,IPR016135,IPR008883,IPR037202; PFAM:PF09454,PF05743; go_process: GO:0006464 - cellular protein modification process [Evidence IEA]; go_process: GO:0015031 - protein transport [Evidence IEA] AKAW2_40501S COG:T; EggNog:ENOG410PQXS; InterPro:IPR027458,IPR000366; PFAM:PF02116; TransMembrane:7 (o31-58i70-93o113-137i149-168o198-219i235-256o262-283i); go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0004932 - mating-type factor pheromone receptor activity [Evidence IEA]; go_process: GO:0007186 - G protein-coupled receptor signaling pathway [Evidence IEA] AKAW2_40502A BUSCO:EOG092619MJ; COG:U; EggNog:ENOG410PI5M; InterPro:IPR001619,IPR043127,IPR036045,IPR043154, IPR027482; PFAM:PF00995; go_process: GO:0006904 - vesicle docking involved in exocytosis [Evidence IEA]; go_process: GO:0016192 - vesicle-mediated transport [Evidence IEA] AKAW2_40503S COG:S; EggNog:ENOG410PPB4; InterPro:IPR035441,IPR000571,IPR036855; PFAM:PF00642; go_function: GO:0046872 - metal ion binding [Evidence IEA] AKAW2_40504S COG:S; EggNog:ENOG410PNAF AKAW2_40505A BUSCO:EOG09264BJC; COG:D; EggNog:ENOG410PFQB; InterPro:IPR036570,IPR003511,IPR027097; PFAM:PF02301; go_process: GO:0007094 - mitotic spindle assembly checkpoint [Evidence IEA] AKAW2_40506S COG:J; EggNog:ENOG410PJNW; InterPro:IPR000640,IPR035654,IPR005225,IPR038363, IPR027417,IPR000795,IPR031157,IPR006297,IPR013842, IPR035647,IPR009000; PFAM:PF06421,PF00009,PF00679,PF01926; go_function: GO:0003924 - GTPase activity [Evidence IEA]; go_function: GO:0005525 - GTP binding [Evidence IEA] AKAW2_40507S COG:K; EggNog:ENOG410PH1P; InterPro:IPR007066,IPR035697,IPR007081,IPR007080, IPR007083,IPR038120,IPR035698,IPR000722,IPR042102, IPR006592; PFAM:PF05000,PF04998,PF04997,PF04983,PF00623; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0003899 - DNA-directed 5'-3' RNA polymerase activity [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA] AKAW2_40508S COG:K; EggNog:ENOG410PQ9A; InterPro:IPR000719,IPR022495,IPR011009,IPR008266; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0004674 - protein serine/threonine kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_40509A COG:E; EggNog:ENOG410PJZC; InterPro:IPR032963,IPR023210,IPR036812; PFAM:PF00248; go_function: GO:0035226 - glutamate-cysteine ligase catalytic subunit binding [Evidence IEA]; go_process: GO:0006750 - glutathione biosynthetic process [Evidence IEA] AKAW2_40510A COG:S; EggNog:ENOG410PJMQ; InterPro:IPR018170,IPR020471,IPR036812,IPR023210; PFAM:PF00248; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_40511S COG:S; EggNog:ENOG410PXIP; InterPro:IPR001138,IPR036864; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_40512A COG:S; EggNog:ENOG410PPS0; InterPro:IPR018571; PFAM:PF09463; TransMembrane:1 (o81-106i) AKAW2_40514S CAZy:GT2_Chitin_synth; COG:M; EggNog:ENOG410PFUV; InterPro:IPR029044,IPR004835,IPR004834,IPR013616; PFAM:PF01644,PF08407,PF13632; TransMembrane:7 (o356-373i385-410o444-461i473-495o515-542i656-676o696- 716i); go_function: GO:0004100 - chitin synthase activity [Evidence IEA]; go_function: GO:0016758 - transferase activity, transferring hexosyl groups [Evidence IEA]; go_process: GO:0006031 - chitin biosynthetic process [Evidence IEA] AKAW2_40515S BUSCO:EOG09265FCK; COG:O; EggNog:ENOG410PN5Z; InterPro:IPR016135,IPR023313,IPR000608; PFAM:PF00179 AKAW2_40516A COG:O; EggNog:ENOG410PT0P; InterPro:IPR014368; TransMembrane:1 (o15-35i); go_function: GO:0004129 - cytochrome-c oxidase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_40517S COG:S; EggNog:ENOG410PQEU; InterPro:IPR037818,IPR019473,IPR009072,IPR006565; PFAM:PF07524,PF10406; go_component: GO:0005669 - transcription factor TFIID complex [Evidence IEA]; go_function: GO:0046982 - protein heterodimerization activity [Evidence IEA] AKAW2_40518A COG:S; EggNog:ENOG410PTUR; InterPro:IPR024645; PFAM:PF11093; go_component: GO:0042720 - mitochondrial inner membrane peptidase complex [Evidence IEA] AKAW2_40519S COG:L; EggNog:ENOG410PX0C; InterPro:IPR027417,IPR030547; go_component: GO:0005657 - replication fork [Evidence IEA]; go_component: GO:0033063 - Rad51B-Rad51C-Rad51D-XRCC2 complex [Evidence IEA]; go_process: GO:0000724 - double-strand break repair via homologous recombination [Evidence IEA]; go_process: GO:0006281 - DNA repair [Evidence IEA] AKAW2_40520A COG:E; EggNog:ENOG410PFC0; InterPro:IPR036052,IPR001926; PFAM:PF00291; antiSMASH:Cluster_4.7 AKAW2_40521S BUSCO:EOG092624KK; COG:J; EggNog:ENOG410PII1; InterPro:IPR002305,IPR002306,IPR014729,IPR001412; PFAM:PF00579; antiSMASH:Cluster_4.7; go_function: GO:0000166 - nucleotide binding [Evidence IEA]; go_function: GO:0004812 - aminoacyl-tRNA ligase activity [Evidence IEA]; go_function: GO:0004830 - tryptophan-tRNA ligase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006418 - tRNA aminoacylation for protein translation [Evidence IEA]; go_process: GO:0006436 - tryptophanyl-tRNA aminoacylation [Evidence IEA] AKAW2_40522A BUSCO:EOG09262N3C; COG:E; EggNog:ENOG410PHY1; InterPro:IPR013023,IPR000506,IPR013116,IPR036291, IPR016207,IPR008927,IPR013328; PFAM:PF01450,PF07991; antiSMASH:Cluster_4.7; go_function: GO:0004455 - ketol-acid reductoisomerase activity [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0009082 - branched-chain amino acid biosynthetic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_40523A COG:S; EggNog:ENOG410PXWQ; TransMembrane:7 (o12-31i43-68o88-110i122-143o163-188i200-226o238-258i); antiSMASH:Cluster_4.7 AKAW2_40524S COG:C; EggNog:ENOG410PICX; InterPro:IPR015590,IPR016161,IPR016162,IPR016163; PFAM:PF00171; SMCOG1017:aldehyde dehydrogenase; antiSMASH:Cluster_4.7; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0016620 - oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_40525S COG:K; EggNog:ENOG410PWCN; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; antiSMASH:Cluster_4.7; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_40526S COG:G; EggNog:ENOG410PMIU; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; SMCOG1169:sugar transport protein; TransMembrane:12 (i118-137o157-174i186-205o211-231i243-267o279-300i351- 371o391-414i435-454o460-481i493-520o526-548i); antiSMASH:Cluster_4.7; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_40527S COG:E; EggNog:ENOG410PIX0; InterPro:IPR004839,IPR015424,IPR015421; PFAM:PF00155; SMCOG1019:aminotransferase; antiSMASH:Cluster_4.7; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0030170 - pyridoxal phosphate binding [Evidence IEA]; go_process: GO:0009058 - biosynthetic process [Evidence IEA] AKAW2_40528S COG:S; EggNog:ENOG410PK33; InterPro:IPR036956,IPR016135,IPR023582,IPR006575, IPR020569,IPR020568,IPR001498; PFAM:PF01205,PF05773; antiSMASH:Cluster_4.7; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_40529A COG:I; EggNog:ENOG410QDSG; InterPro:IPR000873,IPR009081,IPR036736,IPR029058, IPR001031,IPR042099,IPR020845; PFAM:PF00501,PF00550,PF12697,PF00975; SMCOG1002:AMP-dependent synthetase and ligase; antiSMASH:Cluster_4.7; go_function: GO:0016788 - hydrolase activity, acting on ester bonds [Evidence IEA]; go_process: GO:0009058 - biosynthetic process [Evidence IEA] AKAW2_40530A COG:T; EggNog:ENOG410PFXV; InterPro:IPR019826,IPR002018,IPR029058; MEROPS:MER0033188; PFAM:PF00135; SECRETED:SignalP(1-22); antiSMASH:Cluster_4.7 AKAW2_40531A COG:G; EggNog:ENOG410PMG2; InterPro:IPR008922,IPR002227; PFAM:PF00264; SECRETED:SignalP(1-19); antiSMASH:Cluster_4.7; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA] AKAW2_40532S COG:S; EggNog:ENOG410PGF6; InterPro:IPR036291,IPR008030; PFAM:PF13460,PF05368,PF03435; antiSMASH:Cluster_4.7 AKAW2_40533A TransMembrane:1 (i48-65o); antiSMASH:Cluster_4.7 AKAW2_40534S COG:Q; EggNog:ENOG410PUSW; InterPro:IPR015889; antiSMASH:Cluster_4.7; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016702 - oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_40535S CAZy:AA11; COG:S; EggNog:ENOG410PMB9; SECRETED:SignalP(1-20); antiSMASH:Cluster_4.7 AKAW2_40536S BUSCO:EOG0926354S; COG:J; EggNog:ENOG410PGJW; InterPro:IPR002136,IPR013000,IPR025755,IPR023574; PFAM:PF14374,PF00573; antiSMASH:Cluster_4.7; go_component: GO:0005840 - ribosome [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_process: GO:0006412 - translation [Evidence IEA] AKAW2_40537A SECRETED:SignalP(1-17) AKAW2_40538S COG:S; EggNog:ENOG410PIF8; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_40539S COG:O; EggNog:ENOG410PREK; InterPro:IPR024586,IPR001623,IPR036869,IPR018253; PFAM:PF00226,PF11875; TransMembrane:1 (o575-595i) AKAW2_40540S BUSCO:EOG09264DT4; COG:A; EggNog:ENOG410PGB0; InterPro:IPR017862,IPR004015; PFAM:PF02731; go_component: GO:0005681 - spliceosomal complex [Evidence IEA]; go_process: GO:0000398 - mRNA splicing, via spliceosome [Evidence IEA] AKAW2_40541S COG:S; EggNog:ENOG410PI4Y; InterPro:IPR027795; PFAM:PF13840 AKAW2_40542A COG:S; EggNog:ENOG410PJP1; InterPro:IPR036322,IPR015943,IPR001680,IPR019775, IPR020472,IPR017986; PFAM:PF00400; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_40543A COG:D; EggNog:ENOG410PGZ3; InterPro:IPR030379,IPR027417,IPR016491; PFAM:PF00735,PF01926; go_function: GO:0005525 - GTP binding [Evidence IEA] AKAW2_40544S BUSCO:EOG09260E2O; COG:A; EggNog:ENOG410PGWJ; InterPro:IPR027145,IPR036322,IPR015943,IPR001680, IPR007148,IPR019775,IPR020472,IPR017986; PFAM:PF04003,PF00400; SMCOG1173:WD-40 repeat-containing protein; antiSMASH:Cluster_4.8; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_40545A COG:S; EggNog:ENOG410PIQI; InterPro:IPR007325,IPR037175; PFAM:PF04199; antiSMASH:Cluster_4.8; go_function: GO:0004061 - arylformamidase activity [Evidence IEA]; go_process: GO:0019441 - tryptophan catabolic process to kynurenine [Evidence IEA] AKAW2_40546A COG:A; EggNog:ENOG410PGRH; InterPro:IPR027073,IPR040486,IPR040992,IPR004859, IPR016494,IPR041106,IPR041412,IPR041385,IPR014722; PFAM:PF18129,PF18332,PF18334,PF03159,PF17846, PF18194; antiSMASH:Cluster_4.8; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0004527 - exonuclease activity [Evidence IEA]; go_function: GO:0008409 - 5'-3' exonuclease activity [Evidence IEA]; go_process: GO:0000956 - nuclear-transcribed mRNA catabolic process [Evidence IEA] AKAW2_40547S COG:B; EggNog:ENOG410PHNE; InterPro:IPR036322,IPR015943,IPR001680,IPR019775, IPR020472,IPR022052,IPR017986; PFAM:PF12265,PF00400; SMCOG1173:WD-40 repeat-containing protein; antiSMASH:Cluster_4.8; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_40548S COG:H; EggNog:ENOG410PFKM; InterPro:IPR018234,IPR043134,IPR001474,IPR020602, IPR043133; PFAM:PF01227; antiSMASH:Cluster_4.8; go_function: GO:0003934 - GTP cyclohydrolase I activity [Evidence IEA]; go_process: GO:0046654 - tetrahydrofolate biosynthetic process [Evidence IEA] AKAW2_40549S COG:S; EggNog:ENOG410PNWJ; antiSMASH:Cluster_4.8 AKAW2_40551A COG:S; EggNog:ENOG410Q22Y; InterPro:IPR021054; PFAM:PF12296; SECRETED:SignalP(1-23); antiSMASH:Cluster_4.8 AKAW2_40550S COG:Q; EggNog:ENOG410Q2I4; InterPro:IPR016036,IPR016035,IPR016039,IPR018201, IPR042104,IPR014030,IPR011032,IPR013968,IPR013154, IPR001227,IPR032821,IPR014031,IPR014043,IPR020807, IPR020843,IPR020841,IPR029063,IPR036291; PFAM:PF16197,PF00109,PF08659,PF02801,PF00698, PF13602,PF14765,PF00107,PF00106,PF08240; SMCOG1022:Beta-ketoacyl synthase; TransMembrane:1 (o2084-2104i); antiSMASH:Cluster_4.8; go_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein] synthase activity [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0016740 - transferase activity [Evidence IEA]; go_function: GO:0016746 - transferase activity, transferring acyl groups [Evidence IEA]; go_process: GO:0006633 - fatty acid biosynthetic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_40552A COG:S; EggNog:ENOG410PIYI; InterPro:IPR011118,IPR029058; PFAM:PF07519; antiSMASH:Cluster_4.8 AKAW2_40553A antiSMASH:Cluster_4.8 AKAW2_40554A COG:F; EggNog:ENOG410PWTE; InterPro:IPR036157,IPR033704,IPR029054; PFAM:PF00692; antiSMASH:Cluster_4.8 AKAW2_40555S COG:D; EggNog:ENOG410PGKY; InterPro:IPR017441,IPR008271,IPR000719,IPR011009; PFAM:PF07714,PF00069; SMCOG1030:serine/threonine protein kinase; antiSMASH:Cluster_4.8; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_40556S COG:J; EggNog:ENOG410PHFG; InterPro:IPR001040,IPR019770,IPR023398; PFAM:PF01652; antiSMASH:Cluster_4.8; go_component: GO:0005737 - cytoplasm [Evidence IEA]; go_function: GO:0003723 - RNA binding [Evidence IEA]; go_function: GO:0003743 - translation initiation factor activity [Evidence IEA]; go_process: GO:0006413 - translational initiation [Evidence IEA] AKAW2_40557S COG:O; EggNog:ENOG410PNYF; InterPro:IPR003653,IPR038765; MEROPS:MER0011024; PFAM:PF02902; go_function: GO:0008234 - cysteine-type peptidase activity [Evidence IEA]; go_process: GO:0006508 - proteolysis [Evidence IEA] AKAW2_40558A COG:S; EggNog:ENOG410PR1J; InterPro:IPR036568,IPR009288,IPR013024; PFAM:PF06094 AKAW2_40559S BUSCO:EOG09264VC6; COG:U; EggNog:ENOG410PNVJ; InterPro:IPR007653; PFAM:PF04573; TransMembrane:1 (i12-33o); go_component: GO:0005787 - signal peptidase complex [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_process: GO:0006465 - signal peptide processing [Evidence IEA] AKAW2_40560A COG:S; EggNog:ENOG410PRB2; InterPro:IPR000612; PFAM:PF01679; go_component: GO:0016021 - integral component of membrane [Evidence IEA] AKAW2_40561A COG:T; EggNog:ENOG410PINT; InterPro:IPR039028,IPR036784,IPR036890,IPR018955; PFAM:PF10436; go_function: GO:0004672 - protein kinase activity [Evidence IEA] AKAW2_40562S BUSCO:EOG092606AJ; COG:O; EggNog:ENOG410PF84; InterPro:IPR038765,IPR008974,IPR029346,IPR029071, IPR024729,IPR002083,IPR001394,IPR018200,IPR028889; MEROPS:MER0002179; PFAM:PF00917,PF12436,PF14533,PF00443,PF13423; go_function: GO:0004843 - thiol-dependent ubiquitin-specific protease activity [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0006511 - ubiquitin-dependent protein catabolic process [Evidence IEA]; go_process: GO:0016579 - protein deubiquitination [Evidence IEA] AKAW2_40563S COG:U; EggNog:ENOG410PK0H; InterPro:IPR015720,IPR009038,IPR036598; PFAM:PF01105; SECRETED:SignalP(1-20); TransMembrane:1 (n4-15c20/21o176-202i) AKAW2_40564S COG:S; EggNog:ENOG410Q2TF AKAW2_40565S COG:S; EggNog:ENOG410Q255; InterPro:IPR001338; PFAM:PF01185; SECRETED:SignalP(1-24); go_component: GO:0009277 - fungal-type cell wall [Evidence IEA]; go_function: GO:0005199 - structural constituent of cell wall [Evidence IEA] AKAW2_40566A COG:S; EggNog:ENOG410PIP6; InterPro:IPR006569,IPR039037,IPR008942; PFAM:PF04818; go_process: GO:0006874 - cellular calcium ion homeostasis [Evidence IEA] AKAW2_40567A COG:S; EggNog:ENOG410PQCI; SECRETED:SignalP(1-24) AKAW2_40568A COG:S; EggNog:ENOG410PUXW AKAW2_40569A COG:S; EggNog:ENOG410PUXW AKAW2_40570S COG:S; EggNog:ENOG410PZ3I; TransMembrane:1 (i26-44o) AKAW2_40571A COG:S; EggNog:ENOG410PPTK; InterPro:IPR031833; PFAM:PF15932; TransMembrane:1 (o6-25i) AKAW2_40572S BUSCO:EOG09260HSP; COG:L; EggNog:ENOG410PH2J; InterPro:IPR001161,IPR027417,IPR032830,IPR001650, IPR032438,IPR014001,IPR006935; PFAM:PF00271,PF04851,PF13625,PF16203; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0003678 - DNA helicase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016787 - hydrolase activity [Evidence IEA]; go_process: GO:0006289 - nucleotide-excision repair [Evidence IEA]; go_process: GO:0006367 - transcription initiation from RNA polymerase II promoter [Evidence IEA] AKAW2_40573S COG:S; EggNog:ENOG410PIZE; InterPro:IPR025337; PFAM:PF14027; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA] AKAW2_40574S COG:S; EggNog:ENOG410PSXI; antiSMASH:Cluster_4.9 AKAW2_40575A BUSCO:EOG092610LP; COG:H; EggNog:ENOG410PGZM; InterPro:IPR022310,IPR036526,IPR003694,IPR014729, IPR014445,IPR003010; PFAM:PF02540,PF00795; antiSMASH:Cluster_4.9; go_component: GO:0005737 - cytoplasm [Evidence IEA]; go_function: GO:0003952 - NAD+ synthase (glutamine-hydrolyzing) activity [Evidence IEA]; go_function: GO:0004359 - glutaminase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006807 - nitrogen compound metabolic process [Evidence IEA]; go_process: GO:0009435 - NAD biosynthetic process [Evidence IEA] AKAW2_40576S COG:L; EggNog:ENOG410PGJ2; InterPro:IPR000086,IPR020084,IPR015375,IPR015376, IPR015797; PFAM:PF00293,PF09296,PF09297; antiSMASH:Cluster_4.9; go_function: GO:0016787 - hydrolase activity [Evidence IEA]; go_function: GO:0046872 - metal ion binding [Evidence IEA] AKAW2_40577A COG:S; EggNog:ENOG410PR1G; InterPro:IPR012340,IPR011564; PFAM:PF02765; antiSMASH:Cluster_4.9; go_component: GO:0000784 - nuclear chromosome, telomeric region [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_process: GO:0000723 - telomere maintenance [Evidence IEA] AKAW2_40578S COG:Q; EggNog:ENOG410PH78; InterPro:IPR020946,IPR036188,IPR000960; PFAM:PF13738,PF13454,PF13450,PF07992; SMCOG1092:hypothetical protein; antiSMASH:Cluster_4.9; go_function: GO:0004499 - N,N-dimethylaniline monooxygenase activity [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_function: GO:0050661 - NADP binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_40579A COG:S; EggNog:ENOG410PPGK; InterPro:IPR006674,IPR003607; PFAM:PF01966; antiSMASH:Cluster_4.9 AKAW2_40580S COG:S; EggNog:ENOG410Q0H4; InterPro:IPR016197,IPR038609,IPR021006; PFAM:PF11496; antiSMASH:Cluster_4.9; go_component: GO:0070823 - HDA1 complex [Evidence IEA]; go_process: GO:0016575 - histone deacetylation [Evidence IEA] AKAW2_40581A COG:I; EggNog:ENOG410PG86; InterPro:IPR029058,IPR001031; PFAM:PF12697; antiSMASH:Cluster_4.9; go_function: GO:0016788 - hydrolase activity, acting on ester bonds [Evidence IEA]; go_process: GO:0009058 - biosynthetic process [Evidence IEA] AKAW2_40582A COG:I; EggNog:ENOG410PG86; InterPro:IPR016036,IPR032088,IPR016035,IPR030918, IPR016039,IPR018201,IPR042104,IPR014030,IPR014031, IPR001227,IPR006162,IPR014043,IPR020806,IPR020807, IPR020841,IPR009081,IPR036736; PFAM:PF00550,PF02801,PF00698,PF14765,PF00109, PF16073; SMCOG1093:Beta-ketoacyl synthase; antiSMASH:Cluster_4.9; go_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein] synthase activity [Evidence IEA]; go_function: GO:0016740 - transferase activity [Evidence IEA]; go_function: GO:0016746 - transferase activity, transferring acyl groups [Evidence IEA]; go_function: GO:0031177 - phosphopantetheine binding [Evidence IEA]; go_process: GO:0006633 - fatty acid biosynthetic process [Evidence IEA] AKAW2_40583A antiSMASH:Cluster_4.9 AKAW2_40584S COG:D; EggNog:ENOG410PIAQ; InterPro:IPR038765,IPR036028,IPR035553,IPR001452, IPR002931; PFAM:PF01841,PF00018,PF07653; antiSMASH:Cluster_4.9; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_40585A COG:C; EggNog:ENOG410PK2W; InterPro:IPR038763,IPR038222,IPR001667,IPR004097; PFAM:PF02833,PF01368; antiSMASH:Cluster_4.9; go_component: GO:0005737 - cytoplasm [Evidence IEA]; go_function: GO:0016462 - pyrophosphatase activity [Evidence IEA] AKAW2_40586S COG:E; EggNog:ENOG410Q28U; InterPro:IPR036052,IPR001926; PFAM:PF00291; antiSMASH:Cluster_4.9 AKAW2_40587A COG:S; EggNog:ENOG410PFAK; InterPro:IPR001841,IPR001606,IPR019787,IPR019786, IPR036431,IPR011011,IPR003349,IPR004198,IPR001965, IPR013637,IPR003347,IPR013083; PFAM:PF02928,PF01388,PF02375,PF00628,PF02373, PF08429; antiSMASH:Cluster_4.9; go_function: GO:0003677 - DNA binding [Evidence IEA] AKAW2_40588S COG:L; EggNog:ENOG410PGIA; InterPro:IPR035901,IPR027520,IPR000305,IPR013083; PFAM:PF01541; go_component: GO:0033557 - Slx1-Slx4 complex [Evidence IEA]; go_function: GO:0017108 - 5'-flap endonuclease activity [Evidence IEA]; go_process: GO:0006281 - DNA repair [Evidence IEA] AKAW2_40589A BUSCO:EOG09261F9G; COG:F; EggNog:ENOG410PNUS; InterPro:IPR027417,IPR039430,IPR018094,IPR018095; PFAM:PF02223; go_function: GO:0004798 - thymidylate kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006233 - dTDP biosynthetic process [Evidence IEA] AKAW2_40590S COG:A; EggNog:ENOG410PG40; InterPro:IPR002616,IPR028592,IPR036511; PFAM:PF01702; go_function: GO:0008479 - queuine tRNA-ribosyltransferase activity [Evidence IEA]; go_function: GO:0016763 - transferase activity, transferring pentosyl groups [Evidence IEA]; go_process: GO:0006400 - tRNA modification [Evidence IEA] AKAW2_40591A COG:E; EggNog:ENOG410PH5R; InterPro:IPR029041,IPR003171; PFAM:PF02219; go_function: GO:0004489 - methylenetetrahydrofolate reductase (NAD(P)H) activity [Evidence IEA]; go_process: GO:0006555 - methionine metabolic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_40592S COG:S; EggNog:ENOG410PQ65; InterPro:IPR018811; PFAM:PF10306; TransMembrane:1 (o69-93i) AKAW2_40593A BUSCO:EOG09264YKY; COG:F; EggNog:ENOG410PHRW; InterPro:IPR034907,IPR036850,IPR001564,IPR023005; PFAM:PF00334; go_function: GO:0004550 - nucleoside diphosphate kinase activity [Evidence IEA]; go_process: GO:0006165 - nucleoside diphosphate phosphorylation [Evidence IEA]; go_process: GO:0006183 - GTP biosynthetic process [Evidence IEA]; go_process: GO:0006228 - UTP biosynthetic process [Evidence IEA]; go_process: GO:0006241 - CTP biosynthetic process [Evidence IEA] AKAW2_40594S BUSCO:EOG09260B3X; CAZy:GH31; COG:G; EggNog:ENOG410PH3V; InterPro:IPR025887,IPR000322,IPR017853,IPR011013, IPR013780,IPR030458,IPR033403; PFAM:PF13802,PF17137,PF01055; SECRETED:SignalP(1-30); go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_function: GO:0030246 - carbohydrate binding [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_40595S COG:S; EggNog:ENOG410PHKS; InterPro:IPR006603; PFAM:PF04193; TransMembrane:6 (i40-60o66-87i127-148o154-172i184-206o212-232i) AKAW2_40596S COG:S; EggNog:ENOG410PHSK AKAW2_40597S CAZy:GH18; COG:G; EggNog:ENOG410PIRU; InterPro:IPR017853,IPR001223,IPR001579; PFAM:PF00704; SECRETED:SignalP(1-22); go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_40598S COG:O; EggNog:ENOG410PJAB; InterPro:IPR036188,IPR023753; SECRETED:SignalP(1-19); TransMembrane:1 (n6-14c19/20o29-46i); go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_40599A COG:P; EggNog:ENOG410PFW2; InterPro:IPR018303,IPR023298,IPR023299,IPR001757, IPR004014,IPR036412,IPR006534,IPR008250,IPR023214; PFAM:PF00122,PF00690,PF00702; TransMembrane:10 (i144-163o169-185i373-393o405-434i766-787o793-817i829- 847o859-881i893-915o944-962i); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0000166 - nucleotide binding [Evidence IEA]; go_function: GO:0008553 - proton-exporting ATPase activity, phosphorylative mechanism [Evidence IEA]; go_process: GO:0120029 - proton export across plasma membrane [Evidence IEA] AKAW2_40600A COG:J; EggNog:ENOG410PHA7; InterPro:IPR020056,IPR000924,IPR020059,IPR020058, IPR001412,IPR014729,IPR004526,IPR011035,IPR036282; PFAM:PF03950,PF00749; go_component: GO:0005737 - cytoplasm [Evidence IEA]; go_function: GO:0000166 - nucleotide binding [Evidence IEA]; go_function: GO:0004812 - aminoacyl-tRNA ligase activity [Evidence IEA]; go_function: GO:0004818 - glutamate-tRNA ligase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006412 - translation [Evidence IEA]; go_process: GO:0006418 - tRNA aminoacylation for protein translation [Evidence IEA]; go_process: GO:0006424 - glutamyl-tRNA aminoacylation [Evidence IEA]; go_process: GO:0043039 - tRNA aminoacylation [Evidence IEA] AKAW2_40601S BUSCO:EOG092643Y5; COG:J; EggNog:ENOG410PNGA; InterPro:IPR023674,IPR028364,IPR016095; PFAM:PF00687 AKAW2_40602A COG:S; EggNog:ENOG410PNU6; InterPro:IPR024602,IPR009316; PFAM:PF08700,PF06148; go_component: GO:0016020 - membrane [Evidence IEA]; go_process: GO:0007030 - Golgi organization [Evidence IEA]; go_process: GO:0015031 - protein transport [Evidence IEA] AKAW2_40603S COG:S; EggNog:ENOG410Q09M AKAW2_40604A COG:D; EggNog:ENOG410PH4D; InterPro:IPR019591,IPR028600,IPR027417,IPR033756; PFAM:PF01656; go_function: GO:0051539 - 4 iron, 4 sulfur cluster binding [Evidence IEA]; go_process: GO:0016226 - iron-sulfur cluster assembly [Evidence IEA] AKAW2_40605A COG:Y; EggNog:ENOG410PI0B; InterPro:IPR029071,IPR001012,IPR012989,IPR036241; PFAM:PF00789; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_40606A COG:Y; EggNog:ENOG410PI0B; InterPro:IPR009060; PFAM:PF14555; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_40607S COG:U; EggNog:ENOG410PRIF; InterPro:IPR013262; PFAM:PF08219; go_component: GO:0005741 - mitochondrial outer membrane [Evidence IEA] AKAW2_40608S COG:U; EggNog:ENOG410PGAM; InterPro:IPR001708; PFAM:PF02096; TransMembrane:3 (o148-170i301-319o325-343i); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0032977 - membrane insertase activity [Evidence IEA] AKAW2_40609A COG:Q; EggNog:ENOG410PJ8H; InterPro:IPR001128,IPR017972,IPR002401,IPR036396; PFAM:PF00067; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_40610A BUSCO:EOG09263LNF; COG:E; EggNog:ENOG410PHE5; InterPro:IPR001985,IPR018166,IPR016067; PFAM:PF01536; antiSMASH:Cluster_4.10; go_function: GO:0004014 - adenosylmethionine decarboxylase activity [Evidence IEA]; go_process: GO:0006597 - spermine biosynthetic process [Evidence IEA]; go_process: GO:0008295 - spermidine biosynthetic process [Evidence IEA] AKAW2_40611A BUSCO:EOG09260THV; COG:K; EggNog:ENOG410PI43; InterPro:IPR004823,IPR037796,IPR016024,IPR009072, IPR011442; PFAM:PF07571,PF02969; antiSMASH:Cluster_4.10; go_component: GO:0000124 - SAGA complex [Evidence IEA]; go_component: GO:0005669 - transcription factor TFIID complex [Evidence IEA]; go_component: GO:0046695 - SLIK (SAGA-like) complex [Evidence IEA]; go_function: GO:0016251 - RNA polymerase II general transcription initiation factor activity [Evidence IEA]; go_function: GO:0046982 - protein heterodimerization activity [Evidence IEA]; go_process: GO:0006352 - DNA-templated transcription, initiation [Evidence IEA]; go_process: GO:0006367 - transcription initiation from RNA polymerase II promoter [Evidence IEA] AKAW2_40612S COG:S; EggNog:ENOG410PJTY; InterPro:IPR008949,IPR034686; PFAM:PF19086; SMCOG1052:Terpene synthase/cyclase metal-binding domain protein; antiSMASH:Cluster_4.10 AKAW2_40613S COG:L; EggNog:ENOG410PNMG; InterPro:IPR002815,IPR013049,IPR036078,IPR034136; PFAM:PF04406; antiSMASH:Cluster_4.10; go_component: GO:0005694 - chromosome [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016889 - endodeoxyribonuclease activity, producing 3'-phosphomonoesters [Evidence IEA]; go_process: GO:0006259 - DNA metabolic process [Evidence IEA] AKAW2_40614A COG:O; EggNog:ENOG410PHRU; InterPro:IPR016135,IPR023313,IPR000608; PFAM:PF00179; antiSMASH:Cluster_4.10 AKAW2_40615A COG:M; EggNog:ENOG410PGQS; InterPro:IPR005552; PFAM:PF03803; antiSMASH:Cluster_4.10; go_function: GO:0017128 - phospholipid scramblase activity [Evidence IEA]; go_process: GO:0017121 - plasma membrane phospholipid scrambling [Evidence IEA] AKAW2_40616A COG:U; EggNog:ENOG410PS99; InterPro:IPR034543; SECRETED:SignalP(1-20); antiSMASH:Cluster_4.10 AKAW2_40617S BUSCO:EOG09264ZDZ; COG:J; EggNog:ENOG410PP7F; InterPro:IPR018261,IPR001684; PFAM:PF01016; antiSMASH:Cluster_4.10; go_component: GO:0005840 - ribosome [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_process: GO:0006412 - translation [Evidence IEA] AKAW2_40618A COG:L; EggNog:ENOG410PP8M; InterPro:IPR036420,IPR001357,IPR013914; PFAM:PF08605,PF18115,PF00533 AKAW2_40619A BUSCO:EOG09262WXK; COG:J; EggNog:ENOG410PM9P; InterPro:IPR011856,IPR006677,IPR006676,IPR016589, IPR036167; PFAM:PF01974; go_component: GO:0000214 - tRNA-intron endonuclease complex [Evidence IEA]; go_function: GO:0000213 - tRNA-intron endonuclease activity [Evidence IEA]; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0004518 - nuclease activity [Evidence IEA]; go_process: GO:0006388 - tRNA splicing, via endonucleolytic cleavage and ligation [Evidence IEA] AKAW2_40620S COG:A; EggNog:ENOG410PRU4; InterPro:IPR007264,IPR036756; PFAM:PF04135; go_function: GO:0030515 - snoRNA binding [Evidence IEA]; go_process: GO:0001522 - pseudouridine synthesis [Evidence IEA]; go_process: GO:0042254 - ribosome biogenesis [Evidence IEA] AKAW2_40621A BUSCO:EOG092620U5; COG:O; EggNog:ENOG410PG29; InterPro:IPR039907,IPR014881,IPR036283,IPR033411, IPR017117; PFAM:PF08772,PF17146; go_function: GO:0004521 - endoribonuclease activity [Evidence IEA]; go_process: GO:0000469 - cleavage involved in rRNA processing [Evidence IEA]; go_process: GO:0042274 - ribosomal small subunit biogenesis [Evidence IEA] AKAW2_40622S COG:S; EggNog:ENOG410PQIW; TransMembrane:6 (o27-48i60-83o103-126i138-159o187-205i217-238o) AKAW2_40623S COG:K; EggNog:ENOG410Q2N9; InterPro:IPR007219; PFAM:PF04082; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA] AKAW2_40624A COG:S; EggNog:ENOG410PWCM; InterPro:IPR042183,IPR036148,IPR042188,IPR005656; PFAM:PF03972; go_function: GO:0016829 - lyase activity [Evidence IEA] AKAW2_40625A COG:S; EggNog:ENOG410PSSX AKAW2_40626A COG:E; EggNog:ENOG410PH8N; InterPro:IPR001948,IPR023358; MEROPS:MER0001255; PFAM:PF02127; go_function: GO:0004177 - aminopeptidase activity [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006508 - proteolysis [Evidence IEA] AKAW2_40627A CAZy:GH71; COG:G; EggNog:ENOG410PJGT; InterPro:IPR005197; PFAM:PF03659; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_40628S COG:Q; EggNog:ENOG410PHUJ; InterPro:IPR036291,IPR011032,IPR013154,IPR002328; PFAM:PF08240; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_40629S COG:K; EggNog:ENOG410PFVE; InterPro:IPR018287,IPR004827; PFAM:PF00170,PF10297; go_component: GO:0005634 - nucleus [Evidence IEA]; go_function: GO:0003700 - DNA-binding transcription factor activity [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_40630A COG:S; EggNog:ENOG410PHCD; InterPro:IPR023395; TransMembrane:3 (i212-233o253-272i470-489o) AKAW2_40631S COG:C; EggNog:ENOG410PN2J; InterPro:IPR001055,IPR012675,IPR001041,IPR018298, IPR036010; PFAM:PF00111; go_function: GO:0009055 - electron transfer activity [Evidence IEA]; go_function: GO:0051536 - iron-sulfur cluster binding [Evidence IEA]; go_function: GO:0051537 - 2 iron, 2 sulfur cluster binding [Evidence IEA] AKAW2_40632A BUSCO:EOG092653LT; COG:S; EggNog:ENOG410PPB1; InterPro:IPR012459; PFAM:PF07890; go_process: GO:0006364 - rRNA processing [Evidence IEA] AKAW2_40633S BUSCO:EOG09261V9P; COG:U; EggNog:ENOG410PH16; InterPro:IPR022941,IPR000897,IPR027417,IPR003593, IPR036891,IPR013822,IPR042101,IPR004125,IPR006325; PFAM:PF02881,PF02492,PF00448,PF02978; go_component: GO:0048500 - signal recognition particle [Evidence IEA]; go_function: GO:0003924 - GTPase activity [Evidence IEA]; go_function: GO:0005525 - GTP binding [Evidence IEA]; go_function: GO:0008312 - 7S RNA binding [Evidence IEA]; go_process: GO:0006614 - SRP-dependent cotranslational protein targeting to membrane [Evidence IEA] AKAW2_40634A COG:P; EggNog:ENOG410PKAH; InterPro:IPR018946,IPR038607; PFAM:PF09423; TransMembrane:3 (i7-26o32-51i102-123o) AKAW2_40635A COG:S; EggNog:ENOG410PKTT; InterPro:IPR017853,IPR001223,IPR001579; PFAM:PF00704; go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_40636S COG:S; EggNog:ENOG410PV81 AKAW2_40637A COG:S; EggNog:ENOG410Q1FR; TransMembrane:4 (i21-42o54-76i97-121o141-161i) AKAW2_40638S COG:S; EggNog:ENOG410Q12Q; InterPro:IPR011009,IPR002575; PFAM:PF01636 AKAW2_40639A COG:J; EggNog:ENOG410PPHX; InterPro:IPR006175,IPR006056,IPR035959; PFAM:PF01042 AKAW2_40640S CAZy:CE10; COG:V; EggNog:ENOG410PJWW; InterPro:IPR029058,IPR013094; MEROPS:MER0034960; PFAM:PF00326,PF07859; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_40641S COG:G; EggNog:ENOG410PIRU; InterPro:IPR017853 AKAW2_40642S COG:O; EggNog:ENOG410QEA5 AKAW2_40643S COG:I; EggNog:ENOG410PIN1; InterPro:IPR023606,IPR003673; PFAM:PF02515; TransMembrane:2 (i122-139o151-171i); go_function: GO:0008410 - CoA-transferase activity [Evidence IEA] AKAW2_40644S COG:S; EggNog:ENOG410PQ2T AKAW2_40645S COG:B; EggNog:ENOG410PRIP; InterPro:IPR022043; PFAM:PF12253 AKAW2_40646S COG:S; EggNog:ENOG410PJ5G AKAW2_40647S COG:S; EggNog:ENOG410PNFQ; InterPro:IPR007062; PFAM:PF04979; antiSMASH:Cluster_4.11; go_function: GO:0004864 - protein phosphatase inhibitor activity [Evidence IEA]; go_process: GO:0009966 - regulation of signal transduction [Evidence IEA]; go_process: GO:0043666 - regulation of phosphoprotein phosphatase activity [Evidence IEA] AKAW2_40648S COG:U; EggNog:ENOG410PM5W; InterPro:IPR011074,IPR036865,IPR042938,IPR036273, IPR001251; PFAM:PF00650,PF03765; TransMembrane:1 (o334-353i); antiSMASH:Cluster_4.11; go_function: GO:0008526 - phosphatidylinositol transfer activity [Evidence IEA] AKAW2_40649S BUSCO:EOG09260SIZ; COG:I; EggNog:ENOG410PHHR; InterPro:IPR018333,IPR008930,IPR032696,IPR002365, IPR032697; PFAM:PF00432,PF13243,PF13249; antiSMASH:Cluster_4.11; go_component: GO:0005811 - lipid droplet [Evidence IEA]; go_function: GO:0000250 - lanosterol synthase activity [Evidence IEA]; go_function: GO:0016866 - intramolecular transferase activity [Evidence IEA]; go_function: GO:0042300 - beta-amyrin synthase activity [Evidence IEA]; go_process: GO:0016104 - triterpenoid biosynthetic process [Evidence IEA] AKAW2_40650S BUSCO:EOG09264LH2; COG:T; EggNog:ENOG410PFEW; InterPro:IPR011990,IPR008978,IPR007699,IPR007052; PFAM:PF05002,PF04969; antiSMASH:Cluster_4.11; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_40651A COG:S; EggNog:ENOG410PG68; InterPro:IPR006603; PFAM:PF04193; TransMembrane:7 (o13-34i46-67o73-95i217-238o268-287i299-320o340-360i); antiSMASH:Cluster_4.11 AKAW2_40652S COG:B,K; EggNog:ENOG410PGAI; InterPro:IPR029035,IPR003000,IPR026590,IPR026591; PFAM:PF02146; antiSMASH:Cluster_4.11; go_function: GO:0070403 - NAD+ binding [Evidence IEA] AKAW2_40653S COG:D; EggNog:ENOG410PGBA; InterPro:IPR017441,IPR008271,IPR000719,IPR011009; PFAM:PF07714,PF00069; SMCOG1030:serine/threonine protein kinase; antiSMASH:Cluster_4.11; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_40654S COG:S; EggNog:ENOG410PPB9; InterPro:IPR007128; PFAM:PF03980; antiSMASH:Cluster_4.11; go_component: GO:0000818 - nuclear MIS12/MIND complex [Evidence IEA] AKAW2_40655A COG:S; EggNog:ENOG410PM8J; InterPro:IPR011990; antiSMASH:Cluster_4.11; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_40656S COG:S; EggNog:ENOG410PT2U AKAW2_40657S COG:T; EggNog:ENOG410Q15Y; InterPro:IPR000504,IPR012677,IPR002075,IPR035979, IPR018222,IPR039539,IPR032710; PFAM:PF02136,PF00076; go_function: GO:0003676 - nucleic acid binding [Evidence IEA] AKAW2_40658S BUSCO:EOG09261G1Y; COG:O; EggNog:ENOG410PHYZ; InterPro:IPR019805,IPR003594,IPR036890,IPR020575, IPR037196,IPR001404,IPR020568; PFAM:PF13589,PF00183,PF02518; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0051082 - unfolded protein binding [Evidence IEA]; go_process: GO:0006457 - protein folding [Evidence IEA] AKAW2_40659A COG:S; EggNog:ENOG410PI5W; InterPro:IPR030379,IPR027417,IPR025662; TransMembrane:1 (o684-705i); go_function: GO:0005525 - GTP binding [Evidence IEA] AKAW2_40660S COG:K; EggNog:ENOG410PG9G; InterPro:IPR011598,IPR036638; go_function: GO:0046983 - protein dimerization activity [Evidence IEA] AKAW2_40661A BUSCO:EOG092610QT; COG:K; EggNog:ENOG410PIIH; InterPro:IPR013197,IPR036388,IPR036390,IPR008806, IPR039748; PFAM:PF08221,PF05645; go_component: GO:0005666 - RNA polymerase III complex [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0003697 - single-stranded DNA binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA] AKAW2_40662S COG:C; EggNog:ENOG410PJDW; InterPro:IPR007863,IPR011249,IPR011765; MEROPS:MER0003544; PFAM:PF00675,PF05193; go_function: GO:0046872 - metal ion binding [Evidence IEA] AKAW2_40663A BUSCO:EOG09263HD8; COG:C; EggNog:ENOG410PHBV; InterPro:IPR018108,IPR023395; PFAM:PF00153 AKAW2_40664A COG:C; EggNog:ENOG410PFD1; InterPro:IPR019810,IPR002020,IPR010109,IPR036969, IPR016142,IPR016143; PFAM:PF00285; go_function: GO:0004108 - citrate (Si)-synthase activity [Evidence IEA]; go_function: GO:0046912 - transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer [Evidence IEA]; go_process: GO:0006101 - citrate metabolic process [Evidence IEA] AKAW2_40665S BUSCO:EOG092629WA; COG:A; EggNog:ENOG410QEBN; InterPro:IPR000504,IPR035979,IPR012677,IPR006569, IPR008942; PFAM:PF04818,PF00076; go_function: GO:0003676 - nucleic acid binding [Evidence IEA] AKAW2_40666A COG:E; EggNog:ENOG410Q566; InterPro:IPR006235,IPR015424,IPR000277,IPR015421, IPR015422; PFAM:PF01053; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0016765 - transferase activity, transferring alkyl or aryl (other than methyl) groups [Evidence IEA]; go_function: GO:0030170 - pyridoxal phosphate binding [Evidence IEA]; go_process: GO:0006520 - cellular amino acid metabolic process [Evidence IEA]; go_process: GO:0019346 - transsulfuration [Evidence IEA] AKAW2_40667S COG:S; EggNog:ENOG410PSVR; InterPro:IPR008253; PFAM:PF01284; TransMembrane:4 (i7-30o42-65i72-96o108-133i); go_component: GO:0016020 - membrane [Evidence IEA] AKAW2_40668S COG:E; EggNog:ENOG410PF8W; InterPro:IPR004840,IPR004841,IPR004762; PFAM:PF13520,PF00324; TransMembrane:12 (i67-86o92-108i115-131o143-164i171-194o200-224i296- 317o337-362i394-411o423-450i470-494o500-520i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_process: GO:0006865 - amino acid transport [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_40669S COG:I; EggNog:ENOG410PFW5; InterPro:IPR042099,IPR000873,IPR020845; PFAM:PF00501 AKAW2_40670S COG:S; EggNog:ENOG410PQCR; InterPro:IPR039163,IPR019008; PFAM:PF09430; SECRETED:SignalP(1-23); TransMembrane:1 (n3-14c20/21o179-197i) AKAW2_40671A COG:S; EggNog:ENOG410PS4X; InterPro:IPR036020,IPR001202; PFAM:PF00397; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_40672A COG:S; EggNog:ENOG410PN9H; InterPro:IPR015943,IPR001680,IPR036322,IPR037588, IPR019775; go_component: GO:0031931 - TORC1 complex [Evidence IEA]; go_component: GO:0031932 - TORC2 complex [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0031929 - TOR signaling [Evidence IEA] AKAW2_40673A COG:C; EggNog:ENOG410PHVF; InterPro:IPR018108,IPR023395; PFAM:PF00153; TransMembrane:5 (o25-48i78-100o128-148i191-212o232-250i) AKAW2_40674A COG:U; EggNog:ENOG410PI28; InterPro:IPR005225,IPR001806,IPR027417; PFAM:PF00025,PF08477,PF00071,PF01926; go_function: GO:0003924 - GTPase activity [Evidence IEA]; go_function: GO:0005525 - GTP binding [Evidence IEA] AKAW2_40675A COG:E,O; EggNog:ENOG410PGKM; InterPro:IPR014782,IPR033514,IPR042097,IPR024571, IPR034016,IPR001930; MEROPS:MER0019759; PFAM:PF17900,PF01433,PF11838; go_function: GO:0008237 - metallopeptidase activity [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006508 - proteolysis [Evidence IEA] AKAW2_40676S BUSCO:EOG09262ILV; COG:K; EggNog:ENOG410PG5M; InterPro:IPR013087,IPR002035,IPR012170,IPR004595, IPR007198,IPR036465,IPR013083; PFAM:PF04056,PF07975,PF00092,PF13519; go_component: GO:0000439 - transcription factor TFIIH core complex [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006281 - DNA repair [Evidence IEA]; go_process: GO:0006289 - nucleotide-excision repair [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA] AKAW2_40678S COG:S; EggNog:ENOG410PS96; PFAM:PF17733 AKAW2_40677A COG:J; EggNog:ENOG410PJNC; InterPro:IPR001313,IPR016024,IPR011989,IPR033712, IPR033133; PFAM:PF00806; go_function: GO:0003723 - RNA binding [Evidence IEA] AKAW2_40679S COG:G; EggNog:ENOG410PGBX; InterPro:IPR004853; PFAM:PF03151; TransMembrane:9 (i125-142o162-182i203-220o232-252i259-277o283-302i330- 348o390-410i417-449o) AKAW2_40680S COG:C; EggNog:ENOG410PH1J; InterPro:IPR019574,IPR001041,IPR000283,IPR036010, IPR006656,IPR010228,IPR006963,IPR015405; PFAM:PF10588,PF00384,PF13510,PF00111,PF09326; go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0008137 - NADH dehydrogenase (ubiquinone) activity [Evidence IEA]; go_function: GO:0009055 - electron transfer activity [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0016651 - oxidoreductase activity, acting on NAD(P)H [Evidence IEA]; go_function: GO:0051536 - iron-sulfur cluster binding [Evidence IEA]; go_process: GO:0042773 - ATP synthesis coupled electron transport [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_40681A COG:S; EggNog:ENOG410PNZ3; InterPro:IPR010585; PFAM:PF06632; go_component: GO:0005634 - nucleus [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_process: GO:0006302 - double-strand break repair [Evidence IEA]; go_process: GO:0006310 - DNA recombination [Evidence IEA] AKAW2_40682S COG:S; EggNog:ENOG410PJWE; InterPro:IPR034586; go_component: GO:0005816 - spindle pole body [Evidence IEA]; go_component: GO:1990334 - Bfa1-Bub2 complex [Evidence IEA]; go_function: GO:0005096 - GTPase activator activity [Evidence IEA]; go_process: GO:0001100 - negative regulation of exit from mitosis [Evidence IEA] AKAW2_40684A COG:U; EggNog:ENOG410PKGJ; InterPro:IPR000133; PFAM:PF00810; TransMembrane:6 (i38-56o62-80i96-114o120-139i151-168o180-200i); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0046923 - ER retention sequence binding [Evidence IEA]; go_process: GO:0006621 - protein retention in ER lumen [Evidence IEA] AKAW2_40686A COG:A; EggNog:ENOG410PN1S; InterPro:IPR000999,IPR036389; PFAM:PF00636,PF14622; go_function: GO:0004525 - ribonuclease III activity [Evidence IEA]; go_process: GO:0006396 - RNA processing [Evidence IEA] AKAW2_40687S COG:J; EggNog:ENOG410PQRN; InterPro:IPR013219; PFAM:PF08293 AKAW2_40688S BUSCO:EOG09263QUM; COG:A; EggNog:ENOG410PGW8; InterPro:IPR007180,IPR006568; PFAM:PF04046,PF04037; go_component: GO:0005634 - nucleus [Evidence IEA] AKAW2_40689A COG:I; EggNog:ENOG410PGFD; InterPro:IPR006694; PFAM:PF04116; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0008610 - lipid biosynthetic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_40690S BUSCO:EOG09260VCG; COG:S; EggNog:ENOG410PGGZ; InterPro:IPR013946; PFAM:PF08637; TransMembrane:1 (o530-552i) AKAW2_40691S COG:U; EggNog:ENOG410PFGW; InterPro:IPR005225,IPR001806,IPR027417; PFAM:PF00025,PF08477,PF00071; go_function: GO:0003924 - GTPase activity [Evidence IEA]; go_function: GO:0005525 - GTP binding [Evidence IEA] AKAW2_40692S COG:O; EggNog:ENOG410PFJF; InterPro:IPR041569,IPR003959,IPR027417,IPR003593, IPR003960; PFAM:PF00004,PF17862,PF00308; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA] AKAW2_40693S COG:A; EggNog:ENOG410PRD5; InterPro:IPR000504,IPR012677,IPR034201,IPR035979; PFAM:PF00076; go_function: GO:0003676 - nucleic acid binding [Evidence IEA] AKAW2_40694A BUSCO:EOG092600SD; COG:L; EggNog:ENOG410PGIW; InterPro:IPR016024,IPR011990,IPR003152,IPR003151, IPR036940,IPR012993,IPR018936,IPR011009,IPR014009, IPR000403; PFAM:PF08064,PF02260,PF00454,PF02259; go_function: GO:0004674 - protein serine/threonine kinase activity [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_function: GO:0016301 - kinase activity [Evidence IEA] AKAW2_40695A COG:S; EggNog:ENOG410PIMM; InterPro:IPR019721,IPR024549; PFAM:PF12853,PF10785; TransMembrane:2 (i40-57o69-90i) AKAW2_40696S COG:L; EggNog:ENOG410PPZK; InterPro:IPR040038,IPR012923; PFAM:PF07962; go_component: GO:0005634 - nucleus [Evidence IEA]; go_process: GO:0000076 - DNA replication checkpoint [Evidence IEA]; go_process: GO:0006974 - cellular response to DNA damage stimulus [Evidence IEA]; go_process: GO:0048478 - replication fork protection [Evidence IEA] AKAW2_40697A COG:D,Z; EggNog:ENOG410PHJ0; InterPro:IPR009091,IPR000408; PFAM:PF13540,PF00415 AKAW2_40698A COG:H; EggNog:ENOG410PMP3; InterPro:IPR002734,IPR024072; PFAM:PF01872; go_function: GO:0008703 - 5-amino-6-(5-phosphoribosylamino)uracil reductase activity [Evidence IEA]; go_process: GO:0009231 - riboflavin biosynthetic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_40699A COG:D; EggNog:ENOG410PFG0; InterPro:IPR007231; PFAM:PF04097; go_component: GO:0005643 - nuclear pore [Evidence IEA]; go_function: GO:0017056 - structural constituent of nuclear pore [Evidence IEA] AKAW2_40700S COG:U; EggNog:ENOG410PQQ5; InterPro:IPR020164; PFAM:PF14138; TransMembrane:1 (o36-60i); go_component: GO:0031966 - mitochondrial membrane [Evidence IEA] AKAW2_40701S COG:T; EggNog:ENOG410PK3P; InterPro:IPR029021,IPR001763,IPR003595,IPR016130, IPR000242,IPR000387,IPR036873; PFAM:PF00102,PF00581; go_function: GO:0004725 - protein tyrosine phosphatase activity [Evidence IEA]; go_function: GO:0016791 - phosphatase activity [Evidence IEA]; go_process: GO:0006470 - protein dephosphorylation [Evidence IEA]; go_process: GO:0016311 - dephosphorylation [Evidence IEA] AKAW2_40702S COG:S; EggNog:ENOG410PVMI AKAW2_40703A COG:S; EggNog:ENOG410PSWY; SECRETED:SignalP(1-21); TransMembrane:1 (n8-19c31/32o189-205i) AKAW2_40704S COG:G; EggNog:ENOG410Q5AZ; InterPro:IPR018485,IPR018484,IPR006003,IPR043129; PFAM:PF00370,PF02782; go_function: GO:0016773 - phosphotransferase activity, alcohol group as acceptor [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_40705A BUSCO:EOG09260KWP; COG:P; EggNog:ENOG410PGXA; InterPro:IPR004837,IPR005185; PFAM:PF01699,PF03733; TransMembrane:14 (o270-296i405-425o431-454i498-519o539-560i572-592o604- 624i636-659o704-724i924-944o956-981i993-1017o1029- 1049i1061-1079o); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_40706S COG:O; EggNog:ENOG410PJ13; InterPro:IPR041569,IPR003959,IPR027417,IPR003593, IPR032501,IPR003960,IPR005937,IPR035261; PFAM:PF16450,PF00004,PF07724,PF17862,PF07728; go_component: GO:0005737 - cytoplasm [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016787 - hydrolase activity [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA]; go_function: GO:0036402 - proteasome-activating ATPase activity [Evidence IEA]; go_process: GO:0030163 - protein catabolic process [Evidence IEA] AKAW2_40707S COG:S; EggNog:ENOG410PG0N AKAW2_40708S COG:O; EggNog:ENOG410PG2Y; InterPro:IPR042556,IPR032353,IPR042299,IPR004854; PFAM:PF16558,PF03152; go_process: GO:0006511 - ubiquitin-dependent protein catabolic process [Evidence IEA] AKAW2_40709A BUSCO:EOG092643QW; COG:U; EggNog:ENOG410PJZA; InterPro:IPR006977; PFAM:PF04893; TransMembrane:5 (i138-156o162-181i228-246o252-272i284-302o); go_component: GO:0016020 - membrane [Evidence IEA] AKAW2_40710A BUSCO:EOG09263DQH; COG:M; EggNog:ENOG410PGJI; InterPro:IPR000184,IPR039910; PFAM:PF01103; go_component: GO:0019867 - outer membrane [Evidence IEA] AKAW2_40711S COG:O; EggNog:ENOG410PGC6; InterPro:IPR016135,IPR000608; PFAM:PF00179; TransMembrane:1 (i276-293o) AKAW2_40712S COG:C,O; EggNog:ENOG410PHVD; InterPro:IPR000511; PFAM:PF01265; go_component: GO:0005739 - mitochondrion [Evidence IEA]; go_function: GO:0004408 - holocytochrome-c synthase activity [Evidence IEA] AKAW2_40713A COG:S; EggNog:ENOG410PFIZ; InterPro:IPR000719,IPR044095,IPR011009,IPR004147; TransMembrane:1 (o129-149i); go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_40714A COG:S; EggNog:ENOG410PMA3; InterPro:IPR016024,IPR011989,IPR040144; go_function: GO:0005096 - GTPase activator activity [Evidence IEA]; go_process: GO:0043547 - positive regulation of GTPase activity [Evidence IEA] AKAW2_40715S COG:G; EggNog:ENOG410PQTQ; InterPro:IPR013174; PFAM:PF08285; TransMembrane:2 (i7-28o40-63i); go_process: GO:0006486 - protein glycosylation [Evidence IEA] AKAW2_40716A COG:S; EggNog:ENOG410PIW2; InterPro:IPR029057,IPR000836; go_process: GO:0009116 - nucleoside metabolic process [Evidence IEA] AKAW2_40717A COG:P; EggNog:ENOG410PGDK; InterPro:IPR004695,IPR038665,IPR030185; PFAM:PF03595; TransMembrane:10 (i101-122o134-152i173-194o200-227i239-259o271-298i310- 330o350-375i387-410o416-441i); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0015140 - malate transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA]; go_process: GO:0071423 - malate transmembrane transport [Evidence IEA] AKAW2_40718S COG:Q; EggNog:ENOG410PJ47; InterPro:IPR036291,IPR002347,IPR020904; PFAM:PF00106,PF13561; TransMembrane:1 (o263-282i); go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_40719S BUSCO:EOG09262GXD; COG:C; EggNog:ENOG410PFU7; InterPro:IPR016102,IPR011761,IPR017866,IPR005811, IPR013815,IPR005809,IPR013650; PFAM:PF00549,PF13549,PF08442; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0046872 - metal ion binding [Evidence IEA]; go_process: GO:0006099 - tricarboxylic acid cycle [Evidence IEA] AKAW2_40720A COG:S; EggNog:ENOG410PTR7; InterPro:IPR015943,IPR001810,IPR036047; PFAM:PF12937,PF00646; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_40721S COG:K; EggNog:ENOG410PPR1; InterPro:IPR000232,IPR027725,IPR036390,IPR036388; PFAM:PF00447; go_function: GO:0003700 - DNA-binding transcription factor activity [Evidence IEA]; go_function: GO:0043565 - sequence-specific DNA binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_40722A COG:S; EggNog:ENOG410PZCG; InterPro:IPR021641; PFAM:PF11595 AKAW2_40723A COG:S; EggNog:ENOG410PP4M; InterPro:IPR039251,IPR019180; PFAM:PF09791 AKAW2_40724S COG:S; EggNog:ENOG410PPDR AKAW2_40725A COG:J; EggNog:ENOG410PFGM; InterPro:IPR001380,IPR018256; PFAM:PF01294; go_component: GO:0005840 - ribosome [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_process: GO:0006412 - translation [Evidence IEA] AKAW2_40726A COG:S; EggNog:ENOG410PWDP AKAW2_40727S COG:T; EggNog:ENOG410PHR3; InterPro:IPR025875,IPR001611,IPR003591,IPR032675; PFAM:PF12799; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_40728A COG:I; EggNog:ENOG410PKJI; InterPro:IPR016024,IPR026907; PFAM:PF13324; go_process: GO:0051726 - regulation of cell cycle [Evidence IEA] AKAW2_40729S COG:Z; EggNog:ENOG410PI18; InterPro:IPR030054,IPR004000,IPR043129; PFAM:PF00022; go_component: GO:0005634 - nucleus [Evidence IEA]; go_process: GO:0006338 - chromatin remodeling [Evidence IEA] AKAW2_40730S COG:O; EggNog:ENOG410PNWN; InterPro:IPR031127,IPR002867,IPR044066,IPR017907; PFAM:PF01485; go_function: GO:0004842 - ubiquitin-protein transferase activity [Evidence IEA]; go_process: GO:0016567 - protein ubiquitination [Evidence IEA] AKAW2_40731A COG:I; EggNog:ENOG410PKJI; InterPro:IPR006176,IPR006180,IPR022694,IPR006108, IPR036291,IPR008927; PFAM:PF00725,PF02737; go_function: GO:0003857 - 3-hydroxyacyl-CoA dehydrogenase activity [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0070403 - NAD+ binding [Evidence IEA]; go_process: GO:0006631 - fatty acid metabolic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_40732S BUSCO:EOG09260H81; COG:L; EggNog:ENOG410PGK4; InterPro:IPR006906; PFAM:PF04821 AKAW2_40734S COG:S; EggNog:ENOG410PR7M AKAW2_40735S CAZy:GH135; COG:S; EggNog:ENOG410PQH7; InterPro:IPR029167,IPR003961,IPR013783,IPR036116, IPR021986; PFAM:PF12138,PF15474; SECRETED:SignalP(1-21); go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_40737A BUSCO:EOG09261QR8; COG:K; EggNog:ENOG410PI3C; InterPro:IPR004598,IPR040662; PFAM:PF03849,PF18307; go_component: GO:0000439 - transcription factor TFIIH core complex [Evidence IEA]; go_function: GO:0001671 - ATPase activator activity [Evidence IEA]; go_process: GO:0006289 - nucleotide-excision repair [Evidence IEA] AKAW2_40738S COG:Q; EggNog:ENOG410PNGC; InterPro:IPR029069,IPR003736,IPR039298,IPR006683; PFAM:PF03061; go_function: GO:0047617 - acyl-CoA hydrolase activity [Evidence IEA] AKAW2_40739A COG:L; EggNog:ENOG410PJWA; InterPro:IPR041677,IPR027417,IPR041679,IPR026300, IPR032174; PFAM:PF16399,PF13087,PF13086; go_component: GO:0005681 - spliceosomal complex [Evidence IEA]; go_function: GO:0004386 - helicase activity [Evidence IEA]; go_process: GO:0000398 - mRNA splicing, via spliceosome [Evidence IEA] AKAW2_40740S COG:Y; EggNog:ENOG410PKZJ; InterPro:IPR021861; PFAM:PF11957 AKAW2_40741S COG:K; EggNog:ENOG410PIG7; InterPro:IPR001356,IPR009057; PFAM:PF00046; go_function: GO:0003677 - DNA binding [Evidence IEA] AKAW2_40743S COG:U; EggNog:ENOG410Q10Q; InterPro:IPR016024,IPR011989,IPR012295,IPR013041, IPR002553,IPR008152,IPR003164,IPR017104,IPR009028; PFAM:PF01602,PF02296,PF02883; go_component: GO:0030117 - membrane coat [Evidence IEA]; go_component: GO:0030122 - AP-2 adaptor complex [Evidence IEA]; go_component: GO:0030131 - clathrin adaptor complex [Evidence IEA]; go_function: GO:0035615 - clathrin adaptor activity [Evidence IEA]; go_process: GO:0006886 - intracellular protein transport [Evidence IEA]; go_process: GO:0015031 - protein transport [Evidence IEA]; go_process: GO:0016192 - vesicle-mediated transport [Evidence IEA]; go_process: GO:0072583 - clathrin-dependent endocytosis [Evidence IEA] AKAW2_40744A BUSCO:EOG09263BE5; COG:S; EggNog:ENOG410PMCC; InterPro:IPR029066,IPR001608,IPR011078; PFAM:PF01168; go_function: GO:0030170 - pyridoxal phosphate binding [Evidence IEA] AKAW2_40745S COG:S; EggNog:ENOG410Q1GN AKAW2_40746S COG:B; EggNog:ENOG410PG59; InterPro:IPR023696,IPR023801,IPR000286,IPR037138; PFAM:PF00850 AKAW2_40747S COG:S; EggNog:ENOG410PIHF AKAW2_40748A BUSCO:EOG09263RVR; COG:F; EggNog:ENOG410PGME; InterPro:IPR036926,IPR000398,IPR023451,IPR020940; PFAM:PF00303; go_function: GO:0004799 - thymidylate synthase activity [Evidence IEA]; go_process: GO:0006231 - dTMP biosynthetic process [Evidence IEA] AKAW2_40749A COG:A; EggNog:ENOG410PHFC; InterPro:IPR002616,IPR036511,IPR004803; PFAM:PF01702; go_function: GO:0008479 - queuine tRNA-ribosyltransferase activity [Evidence IEA]; go_function: GO:0016763 - transferase activity, transferring pentosyl groups [Evidence IEA]; go_process: GO:0006400 - tRNA modification [Evidence IEA]; go_process: GO:0101030 - tRNA-guanine transglycosylation [Evidence IEA] AKAW2_40750S COG:G; EggNog:ENOG410PIP0; InterPro:IPR011701,IPR036259; PFAM:PF07690; TransMembrane:11 (o88-108i120-141o147-167i179-200o212-234i286-310o322- 339i346-366o372-396i408-428o440-462i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_40751A COG:S; EggNog:ENOG410PSCM AKAW2_40752A COG:S; EggNog:ENOG410PK8J AKAW2_40754A COG:S; EggNog:ENOG410PR6R; InterPro:IPR036867,IPR025952,IPR039629; PFAM:PF13902; go_function: GO:0003676 - nucleic acid binding [Evidence IEA] AKAW2_40755S COG:E; EggNog:ENOG410PGV8; InterPro:IPR007484; MEROPS:MER0032443; PFAM:PF01546,PF04389; SECRETED:SignalP(1-19) AKAW2_40756S COG:F,P; EggNog:ENOG410PVMK; InterPro:IPR000760; PFAM:PF00459; go_process: GO:0046855 - inositol phosphate dephosphorylation [Evidence IEA] AKAW2_40757S COG:S; EggNog:ENOG410PIIJ; InterPro:IPR013920; PFAM:PF08611; TransMembrane:7 (i21-40o60-86i98-119o152-174i186-204o210-229i236-255o) AKAW2_40758S CAZy:GT2_Chitin_synth; COG:M; EggNog:ENOG410PF8Q; InterPro:IPR029044,IPR004835,IPR004834,IPR013616; PFAM:PF01644,PF08407; TransMembrane:7 (o664-683i703-723o743-761i773-796o816-839i944-964o976- 1005i); go_function: GO:0004100 - chitin synthase activity [Evidence IEA]; go_function: GO:0016758 - transferase activity, transferring hexosyl groups [Evidence IEA]; go_process: GO:0006031 - chitin biosynthetic process [Evidence IEA] AKAW2_40759A COG:I,J,T; EggNog:ENOG410PFMP; InterPro:IPR023631,IPR036928,IPR020556; PFAM:PF01425 AKAW2_40760A COG:P; EggNog:ENOG410PHDN; InterPro:IPR027469,IPR002524; PFAM:PF01545; TransMembrane:6 (i12-31o37-58i79-101o113-134i194-220o232-252i); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0008324 - cation transmembrane transporter activity [Evidence IEA]; go_process: GO:0006812 - cation transport [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_40761A COG:P; EggNog:ENOG410PFFZ; InterPro:IPR018028,IPR002818,IPR029062,IPR020835, IPR011614,IPR002226,IPR043156,IPR041399,IPR024712, IPR037060,IPR010582; PFAM:PF01965,PF18011,PF00199,PF06628; go_function: GO:0004096 - catalase activity [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0006979 - response to oxidative stress [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_40762A BUSCO:EOG09262OJ4; COG:S; EggNog:ENOG410PFGJ; InterPro:IPR027417,IPR005654; PFAM:PF03969; go_function: GO:0005524 - ATP binding [Evidence IEA] AKAW2_40763A COG:C; EggNog:ENOG410PGTP; InterPro:IPR001452,IPR030507,IPR035550,IPR036028, IPR035549,IPR001683,IPR036871,IPR000270; PFAM:PF00018,PF00564,PF00787; go_function: GO:0005515 - protein binding [Evidence IEA]; go_function: GO:0035091 - phosphatidylinositol binding [Evidence IEA]; go_process: GO:0000902 - cell morphogenesis [Evidence IEA] AKAW2_40764A BUSCO:EOG092625AX; COG:K; EggNog:ENOG410PG7F; InterPro:IPR005062; PFAM:PF03399 AKAW2_40765S BUSCO:EOG09262LQT; COG:U; EggNog:ENOG410PJAT; InterPro:IPR040608,IPR037855,IPR036443,IPR036388, IPR011993,IPR036390,IPR021648,IPR031558,IPR001876; PFAM:PF11605,PF16988,PF04157; go_component: GO:0000814 - ESCRT II complex [Evidence IEA]; go_function: GO:0032266 - phosphatidylinositol-3-phosphate binding [Evidence IEA]; go_function: GO:0043130 - ubiquitin binding [Evidence IEA]; go_process: GO:0032509 - endosome transport via multivesicular body sorting pathway [Evidence IEA] AKAW2_40766S COG:S; EggNog:ENOG410Q0GA AKAW2_40767A COG:S; EggNog:ENOG410Q287 AKAW2_40768S COG:J; EggNog:ENOG410PQ35; InterPro:IPR006175,IPR006056,IPR035959; PFAM:PF01042 AKAW2_40770S COG:S; EggNog:ENOG410PPSJ; InterPro:IPR039295; SECRETED:SignalP(1-23); TransMembrane:1 (n7-18c23/24o898-920i); go_component: GO:0005887 - integral component of plasma membrane [Evidence IEA]; go_function: GO:0005034 - osmosensor activity [Evidence IEA]; go_process: GO:0007232 - osmosensory signaling pathway via Sho1 osmosensor [Evidence IEA] AKAW2_40771A COG:S; EggNog:ENOG410PFDD; InterPro:IPR019560; PFAM:PF10558; TransMembrane:1 (i218-240o) AKAW2_40772S COG:S; EggNog:ENOG410PTHS; InterPro:IPR021278; PFAM:PF11022; TransMembrane:1 (o12-32i) AKAW2_40773S COG:S; EggNog:ENOG410PTZF; InterPro:IPR037143,IPR002582,IPR008278; PFAM:PF01648; go_function: GO:0000287 - magnesium ion binding [Evidence IEA]; go_function: GO:0008897 - holo-[acyl-carrier-protein] synthase activity [Evidence IEA]; go_process: GO:0006633 - fatty acid biosynthetic process [Evidence IEA] AKAW2_40774S BUSCO:EOG09263UCR; COG:E; EggNog:ENOG410PJ4P; InterPro:IPR004013,IPR016195,IPR010140; PFAM:PF02811; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0004401 - histidinol-phosphatase activity [Evidence IEA]; go_process: GO:0000105 - histidine biosynthetic process [Evidence IEA] AKAW2_40775S COG:O; EggNog:ENOG410PYSU; InterPro:IPR001179; PFAM:PF00254; go_function: GO:0003755 - peptidyl-prolyl cis-trans isomerase activity [Evidence IEA] AKAW2_40776A COG:T; EggNog:ENOG410PVAP; InterPro:IPR019826,IPR002018,IPR029058; MEROPS:MER0033198; PFAM:PF00135; SECRETED:SignalP(1-19) AKAW2_40777A COG:S; EggNog:ENOG410PNKM; InterPro:IPR036779 AKAW2_40778A COG:O; EggNog:ENOG410PHS8; InterPro:IPR041569,IPR003959,IPR027417,IPR003593, IPR003960; PFAM:PF00004,PF17862,PF05496; TransMembrane:1 (i12-34o); go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA] AKAW2_40779S COG:S; EggNog:ENOG410PNGY; InterPro:IPR040349,IPR020981,IPR038608; PFAM:PF12539; go_component: GO:0033551 - monopolin complex [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_40780S BUSCO:EOG09260KDB; COG:G; EggNog:ENOG410PGMQ; InterPro:IPR007070,IPR037671,IPR017852,IPR017850, IPR000917; PFAM:PF01663,PF04987; TransMembrane:15 (n7-16c21/22o462-486i498-519o525-541i553-577o589-607i614- 634o640-660i681-700o720-739i744-762o768-784i830-852o872- 892i904-923o935-955i); go_component: GO:0005789 - endoplasmic reticulum membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0008484 - sulfuric ester hydrolase activity [Evidence IEA]; go_function: GO:0016740 - transferase activity [Evidence IEA]; go_function: GO:0051377 - mannose-ethanolamine phosphotransferase activity [Evidence IEA]; go_process: GO:0006506 - GPI anchor biosynthetic process [Evidence IEA] AKAW2_40781S COG:K; EggNog:ENOG410PH0A; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; TransMembrane:1 (o565-583i); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_40782S COG:E; EggNog:ENOG410PHQJ; InterPro:IPR006238,IPR015424,IPR000277,IPR015421, IPR015422; PFAM:PF01053; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0004121 - cystathionine beta-lyase activity [Evidence IEA]; go_function: GO:0030170 - pyridoxal phosphate binding [Evidence IEA]; go_process: GO:0019346 - transsulfuration [Evidence IEA]; go_process: GO:0071266 - 'de novo' L-methionine biosynthetic process [Evidence IEA] AKAW2_40783S COG:S; EggNog:ENOG410PHXA; InterPro:IPR038781 AKAW2_40784A COG:P,Q; EggNog:ENOG410PI0A; InterPro:IPR030155,IPR013112,IPR017927,IPR013130, IPR013121,IPR039261; PFAM:PF08022,PF01794,PF08030; TransMembrane:7 (o44-65i106-130o150-169i190-208o223-244i251-269o275-295i); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0000293 - ferric-chelate reductase activity [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_40785A COG:E; EggNog:ENOG410PM0C; InterPro:IPR001763,IPR001926,IPR036052,IPR036873; PFAM:PF00291,PF00581 AKAW2_40786S COG:G; EggNog:ENOG410PIWG; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (o46-67i119-138o144-166i178-204o210-233i245-265o277- 296i316-337o357-377i384-401o413-432i521-541o); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_40787A COG:O; EggNog:ENOG410PM7B; InterPro:IPR044066; TransMembrane:2 (i426-446o452-472i) AKAW2_40788S COG:S; EggNog:ENOG410Q11V; InterPro:IPR011009,IPR002575; PFAM:PF01636 AKAW2_40789A COG:Q; EggNog:ENOG410PHNB; InterPro:IPR029069,IPR002539,IPR036291,IPR002347, IPR020904; PFAM:PF00106,PF13561,PF01575,PF08659; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_40790S BUSCO:EOG09261ONU; COG:G; EggNog:ENOG410PFM4; InterPro:IPR027417 AKAW2_40791A BUSCO:EOG09264P3R; COG:J; EggNog:ENOG410PGRR; InterPro:IPR012988,IPR023106,IPR036919,IPR018038, IPR039699,IPR016082,IPR035808,IPR005998; PFAM:PF08079,PF00327; go_component: GO:0022625 - cytosolic large ribosomal subunit [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_process: GO:0000463 - maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [Evidence IEA] AKAW2_40792S BUSCO:EOG0926477X; COG:K; EggNog:ENOG410PHTS; InterPro:IPR016689,IPR040608,IPR036390,IPR036388; PFAM:PF04157; go_component: GO:0000814 - ESCRT II complex [Evidence IEA]; go_process: GO:0071985 - multivesicular body sorting pathway [Evidence IEA] AKAW2_40793A BUSCO:EOG092616QN; COG:J; EggNog:ENOG410PGWD; InterPro:IPR036388,IPR036390,IPR027516,IPR008905, IPR000717; PFAM:PF01399; go_component: GO:0005852 - eukaryotic translation initiation factor 3 complex [Evidence IEA]; go_function: GO:0003723 - RNA binding [Evidence IEA]; go_function: GO:0003743 - translation initiation factor activity [Evidence IEA]; go_function: GO:0031369 - translation initiation factor binding [Evidence IEA]; go_process: GO:0006413 - translational initiation [Evidence IEA] AKAW2_40794A COG:T; EggNog:ENOG410PGCF; InterPro:IPR017441,IPR008271,IPR000719,IPR011009; PFAM:PF07714,PF00069; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_40795S COG:L; EggNog:ENOG410PHAN; InterPro:IPR038718,IPR000330,IPR027417,IPR014001, IPR001650; PFAM:PF00176,PF00271,PF04851; go_function: GO:0005524 - ATP binding [Evidence IEA] AKAW2_40796S COG:S; EggNog:ENOG410PYP3; SECRETED:SignalP(1-16) AKAW2_40797S COG:S; EggNog:ENOG410PPT6; SECRETED:SignalP(1-22); TransMembrane:1 (n7-17c22/23o258-280i) AKAW2_40799S TransMembrane:1 (o75-93i) AKAW2_40798A COG:S; EggNog:ENOG410PU5B; InterPro:IPR021627; PFAM:PF11571; go_component: GO:0016592 - mediator complex [Evidence IEA] AKAW2_40800A COG:Q; EggNog:ENOG410PGYE; InterPro:IPR002402,IPR002974,IPR036396,IPR017972, IPR001128; PFAM:PF00067; go_function: GO:0004497 - monooxygenase activity [Evidence IEA]; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0016712 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_40801A COG:O; EggNog:ENOG410PG2D; InterPro:IPR008758,IPR029058; MEROPS:MER0093133; go_function: GO:0008236 - serine-type peptidase activity [Evidence IEA]; go_process: GO:0006508 - proteolysis [Evidence IEA] AKAW2_40802S COG:G; EggNog:ENOG410PIYF; InterPro:IPR014718,IPR011013,IPR016590,IPR015364; SECRETED:SignalP(1-20); go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0016837 - carbon-oxygen lyase activity, acting on polysaccharides [Evidence IEA]; go_function: GO:0030246 - carbohydrate binding [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_40803S CAZy:PL4; COG:G; EggNog:ENOG410PIYF; InterPro:IPR008979,IPR013784,IPR014718,IPR011013, IPR015364,IPR016590,IPR029413,IPR029411; PFAM:PF09284,PF14686,PF14683; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0016837 - carbon-oxygen lyase activity, acting on polysaccharides [Evidence IEA]; go_function: GO:0030246 - carbohydrate binding [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_40804A COG:F; EggNog:ENOG410PG2G; InterPro:IPR011059,IPR006680,IPR032466; MEROPS:MER0037714; PFAM:PF01979; TransMembrane:1 (o517-535i); go_function: GO:0016787 - hydrolase activity [Evidence IEA]; go_function: GO:0016810 - hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [Evidence IEA] AKAW2_40805A BUSCO:EOG09260DBG; COG:E; EggNog:ENOG410PGZA; InterPro:IPR015422,IPR015424,IPR003437,IPR015421, IPR020581; PFAM:PF01212,PF02347; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0004375 - glycine dehydrogenase (decarboxylating) activity [Evidence IEA]; go_process: GO:0006544 - glycine metabolic process [Evidence IEA]; go_process: GO:0006546 - glycine catabolic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_40806A COG:G; EggNog:ENOG410QDIV; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:9 (i12-31o37-60i72-93o105-128i179-201o213-234i246-264o270- 291i303-324o); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_40807A COG:G; EggNog:ENOG410QDIV AKAW2_40808S COG:E; EggNog:ENOG410PJXM; InterPro:IPR023696,IPR006035; PFAM:PF00491; go_function: GO:0046872 - metal ion binding [Evidence IEA] AKAW2_40809A COG:S; EggNog:ENOG410PQHJ; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_40810A COG:T; EggNog:ENOG410Q23Q; InterPro:IPR000719,IPR011009; PFAM:PF00069; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_40811A COG:S; EggNog:ENOG410PP0G; InterPro:IPR006680,IPR032466,IPR032465; PFAM:PF04909; go_function: GO:0016787 - hydrolase activity [Evidence IEA]; go_function: GO:0016831 - carboxy-lyase activity [Evidence IEA] AKAW2_40812S COG:Q; EggNog:ENOG410PKMD; InterPro:IPR001128,IPR017972,IPR002401,IPR036396; PFAM:PF00067; TransMembrane:1 (o20-40i); go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_40813A CAZy:CE10; COG:I; EggNog:ENOG410PR6J; InterPro:IPR029058,IPR013094; PFAM:PF10340,PF07859; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_40814S COG:S; EggNog:ENOG410PNBP; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; TransMembrane:1 (o653-672i); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_40815S COG:P; EggNog:ENOG410PFFN; InterPro:IPR025700,IPR036188; PFAM:PF07992,PF13450 AKAW2_40816S COG:P; EggNog:ENOG410PFFN; InterPro:IPR036188; TransMembrane:1 (o222-240i) AKAW2_40817S COG:Q; EggNog:ENOG410PMU0; InterPro:IPR002347,IPR036291,IPR020904; PFAM:PF00106,PF13561,PF08659; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_40818S COG:S; EggNog:ENOG410PR0U; SECRETED:SignalP(1-19) AKAW2_40819S COG:Q; EggNog:ENOG410PHTQ; InterPro:IPR013154,IPR013149,IPR036291,IPR011032, IPR020843; PFAM:PF00107,PF08240,PF13602; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_40821A COG:S; EggNog:ENOG410PXQZ; InterPro:IPR006603; PFAM:PF04193; SECRETED:SignalP(1-19); TransMembrane:5 (n4-14c19/20o84-105i117-137o163-186i239-257o277-296i) AKAW2_40822A COG:S; EggNog:ENOG410PKQW; InterPro:IPR037460,IPR036514; go_function: GO:0016788 - hydrolase activity, acting on ester bonds [Evidence IEA] AKAW2_40823A COG:S; EggNog:ENOG410PX36 AKAW2_40825A CAZy:GH79; COG:S; EggNog:ENOG410PNH0; InterPro:IPR017853,IPR031728; PFAM:PF16862 AKAW2_40826A COG:F; EggNog:ENOG410PK0Y; InterPro:IPR022761,IPR019468,IPR024083,IPR008948, IPR000362; PFAM:PF10397,PF00206; go_function: GO:0003824 - catalytic activity [Evidence IEA] AKAW2_40827S COG:G; EggNog:ENOG410PKV4; InterPro:IPR005829,IPR005828,IPR003663,IPR036259, IPR020846; PFAM:PF00083,PF07690; TransMembrane:12 (i7-26o61-82i94-116o122-141i153-172o184-205i269-292o312- 332i339-358o370-395i416-433o439-456i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_40828S COG:S; EggNog:ENOG410PYUP; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_40829A COG:G; EggNog:ENOG410QDJ1; InterPro:IPR011701,IPR036259; PFAM:PF07690; TransMembrane:10 (i104-128o148-174i186-207o219-239i288-307o327-344i351- 372o378-399i411-430o442-464i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_40830A COG:S; EggNog:ENOG410PMPE; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_40831A COG:S; EggNog:ENOG410PJSU; InterPro:IPR007325,IPR037175; PFAM:PF04199; go_function: GO:0004061 - arylformamidase activity [Evidence IEA]; go_process: GO:0019441 - tryptophan catabolic process to kynurenine [Evidence IEA] AKAW2_40832S COG:I; EggNog:ENOG410PG69 AKAW2_40833S COG:I; EggNog:ENOG410PG69; InterPro:IPR023606,IPR025496,IPR003673; PFAM:PF02515,PF14330; go_function: GO:0008410 - CoA-transferase activity [Evidence IEA] AKAW2_40834A COG:S; EggNog:ENOG410PYWD; InterPro:IPR002733; SECRETED:SignalP(1-20) AKAW2_40835A CAZy:PL27; COG:S; EggNog:ENOG410PUG6; SECRETED:SignalP(1-19) AKAW2_40836S COG:O; EggNog:ENOG410PQ0A; InterPro:IPR024079; go_function: GO:0008237 - metallopeptidase activity [Evidence IEA] AKAW2_40837S COG:S; EggNog:ENOG410PK7F; InterPro:IPR011009,IPR002575; PFAM:PF01636 AKAW2_40838S COG:U; EggNog:ENOG410PKJR; InterPro:IPR011701,IPR036259; PFAM:PF07690,PF00083; TransMembrane:12 (i72-92o127-147i154-175o181-198i210-232o248-267i366- 385o405-424i431-450o456-473i485-504o524-547i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_40839S COG:Q; EggNog:ENOG410PHF1; InterPro:IPR032710 AKAW2_40840A COG:E; EggNog:ENOG410PH2G; InterPro:IPR026956,IPR029066,IPR042208,IPR001608; PFAM:PF01168,PF14031 AKAW2_40841A COG:E; EggNog:ENOG410PWKH; InterPro:IPR014746,IPR008146; PFAM:PF00120; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0004356 - glutamate-ammonia ligase activity [Evidence IEA]; go_process: GO:0006807 - nitrogen compound metabolic process [Evidence IEA] AKAW2_40842S COG:F; EggNog:ENOG410PFRT; InterPro:IPR029062,IPR017926; MEROPS:MER0043475; PFAM:PF00117 AKAW2_40843S COG:C; EggNog:ENOG410PUWE; InterPro:IPR015590,IPR029510,IPR016160,IPR016161, IPR016162,IPR016163; PFAM:PF00171; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0016620 - oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_40844S COG:Q; EggNog:ENOG410PUCA; InterPro:IPR036291,IPR002347; PFAM:PF08659,PF00106,PF13561; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_40845A COG:S; EggNog:ENOG410PM04; InterPro:IPR036864,IPR021858,IPR001138; PFAM:PF00172,PF11951; TransMembrane:1 (o352-373i); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_40846A COG:E; EggNog:ENOG410PH2G; InterPro:IPR026956,IPR029066,IPR042208,IPR001608; PFAM:PF01168,PF14031 AKAW2_40847A COG:S; EggNog:ENOG410PX35; InterPro:IPR011009 AKAW2_40848A COG:S; EggNog:ENOG410PWPU; InterPro:IPR018247,IPR013087 AKAW2_40849S COG:S; EggNog:ENOG410PSCX AKAW2_40850A COG:O; EggNog:ENOG410PNYX; InterPro:IPR036852,IPR000209,IPR015500; MEROPS:MER0000333; PFAM:PF00082; go_function: GO:0004252 - serine-type endopeptidase activity [Evidence IEA]; go_function: GO:0008236 - serine-type peptidase activity [Evidence IEA]; go_process: GO:0006508 - proteolysis [Evidence IEA] AKAW2_40851A COG:G; EggNog:ENOG410PJKR; InterPro:IPR011701,IPR036259; TransMembrane:12 (i70-93o113-131i138-158o164-186i198-219o231-251i272- 293o313-332i339-358o364-388i400-423o429-450i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_40852A COG:S; EggNog:ENOG410PH8E; InterPro:IPR007312; PFAM:PF04185; SECRETED:SignalP(1-19); go_function: GO:0016788 - hydrolase activity, acting on ester bonds [Evidence IEA] AKAW2_40853A BUSCO:EOG092634M1; COG:O; EggNog:ENOG410PGPX; InterPro:IPR001623,IPR036869,IPR042569,IPR032003, IPR018253; PFAM:PF16717,PF00226 AKAW2_40854S COG:A; EggNog:ENOG410PSY1; InterPro:IPR008011; PFAM:PF05347 AKAW2_40855A BUSCO:EOG09263BDA; COG:A; EggNog:ENOG410PH4S; InterPro:IPR000504,IPR035979,IPR034356,IPR012677, IPR039171; PFAM:PF00076; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0003723 - RNA binding [Evidence IEA] AKAW2_40856S COG:H; EggNog:ENOG410PH10; InterPro:IPR030384,IPR029063,IPR013216,IPR013705; PFAM:PF01135,PF13649,PF08498,PF08242,PF02353, PF08241,PF13489,PF13847; go_function: GO:0008168 - methyltransferase activity [Evidence IEA]; go_process: GO:0006694 - steroid biosynthetic process [Evidence IEA] AKAW2_40857A COG:G; EggNog:ENOG410PGCT; InterPro:IPR005829,IPR005828,IPR003663,IPR036259, IPR020846; PFAM:PF00083,PF07690; TransMembrane:12 (i38-57o77-100i107-133o139-159i171-189o195-218i288- 309o329-347i354-377o389-412i424-441o453-472i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_40858A CAZy:GH145; COG:S; EggNog:ENOG410PMFZ; PFAM:PF15892 AKAW2_40859S CAZy:GH79; COG:G; EggNog:ENOG410PKWQ; InterPro:IPR017853,IPR031728; PFAM:PF16862 AKAW2_40860S COG:S; EggNog:ENOG410PH34; InterPro:IPR022703; PFAM:PF12051; TransMembrane:5 (i43-61o241-264i285-310o330-353i365-385o) AKAW2_40861S COG:Q; EggNog:ENOG410PFFP; InterPro:IPR020946,IPR036188; go_function: GO:0004499 - N,N-dimethylaniline monooxygenase activity [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_function: GO:0050661 - NADP binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_40862S COG:S; EggNog:ENOG410PJX8; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_40863S COG:G; EggNog:ENOG410QDAG; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:11 (o47-73i94-115o121-143i155-177o183-203i215-236o299- 323i344-363o375-402i414-434o449-467i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_40864A COG:S; EggNog:ENOG410PTEQ AKAW2_40865A COG:S; EggNog:ENOG410PKX0; InterPro:IPR000182,IPR016181; PFAM:PF00583; TransMembrane:2 (i43-63o78-98i); go_function: GO:0008080 - N-acetyltransferase activity [Evidence IEA] AKAW2_40866A COG:P; EggNog:ENOG410PMIK; InterPro:IPR005829,IPR005828,IPR020846,IPR036259; TransMembrane:8 (i121-140o146-167i188-210o222-240i252-270o282-301i313- 333o384-406i); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_40867A COG:P; EggNog:ENOG410PKFV; InterPro:IPR006153,IPR038770; PFAM:PF00999; TransMembrane:13 (o16-33i40-58o70-87i99-123o129-150i162-181o201-219i240- 261o267-283i357-376o382-403i509-530o550-573i); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0015299 - solute:proton antiporter activity [Evidence IEA]; go_process: GO:0006812 - cation transport [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_40868S SECRETED:SignalP(1-20) AKAW2_40869A COG:A; EggNog:ENOG410PFMB; InterPro:IPR027417,IPR014001,IPR001650,IPR011545; PFAM:PF04851,PF00271,PF00270; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA] AKAW2_40870S COG:S; EggNog:ENOG410PJV9; InterPro:IPR009078,IPR017941,IPR007402,IPR036922; PFAM:PF00355,PF04305; go_function: GO:0051537 - 2 iron, 2 sulfur cluster binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_40871A CAZy:GH3; COG:G; EggNog:ENOG410PINP; InterPro:IPR017853,IPR019800,IPR036962,IPR002772, IPR036881,IPR026891,IPR013783,IPR001764; PFAM:PF14310,PF00933,PF01915; go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_40872A COG:G; EggNog:ENOG410PJDI; InterPro:IPR002241,IPR008979,IPR041233,IPR017853, IPR013780,IPR013785; PFAM:PF17801,PF16499; SECRETED:SignalP(1-18); go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_40873S COG:M; EggNog:ENOG410PPG2; InterPro:IPR011761,IPR016185,IPR011095,IPR013815; PFAM:PF07478; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0008716 - D-alanine-D-alanine ligase activity [Evidence IEA]; go_function: GO:0046872 - metal ion binding [Evidence IEA] AKAW2_40874S COG:S; EggNog:ENOG410PQHQ; SECRETED:SignalP(1-21) AKAW2_40876S COG:O; EggNog:ENOG410Q2SI; SECRETED:SignalP(1-21); antiSMASH:Cluster_4.12 AKAW2_40875A COG:E; EggNog:ENOG410PFV8; InterPro:IPR002293; PFAM:PF13520; SMCOG1038:phenylalanine-specific permease; TransMembrane:6 (i37-61o73-91i98-119o148-168i180-204o236-257i); antiSMASH:Cluster_4.12; go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_40877A BUSCO:EOG09263HED; COG:C; EggNog:ENOG410PI6Y; InterPro:IPR018108,IPR023395; PFAM:PF00153; antiSMASH:Cluster_4.12 AKAW2_40878A COG:O; EggNog:ENOG410PM8X; InterPro:IPR027417,IPR003593,IPR003959; PFAM:PF00004; antiSMASH:Cluster_4.12; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA] AKAW2_40879A COG:S; EggNog:ENOG410PT8P; InterPro:IPR020844,IPR004827,IPR021833; PFAM:PF11905; antiSMASH:Cluster_4.12; go_function: GO:0003700 - DNA-binding transcription factor activity [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA]; go_process: GO:0007623 - circadian rhythm [Evidence IEA] AKAW2_40880A COG:S; EggNog:ENOG410PT8P; InterPro:IPR003817; PFAM:PF02666; antiSMASH:Cluster_4.12; go_function: GO:0004609 - phosphatidylserine decarboxylase activity [Evidence IEA]; go_process: GO:0008654 - phospholipid biosynthetic process [Evidence IEA] AKAW2_40881S COG:S; EggNog:ENOG410QDH4; InterPro:IPR010619,IPR024528; PFAM:PF06738,PF12821; TransMembrane:10 (i461-479o485-504i513-532o544-566i587-608o628-645i657- 674o680-697i704-728o762-788i); antiSMASH:Cluster_4.12 AKAW2_40882A COG:S; EggNog:ENOG410PPPK; TransMembrane:6 (i47-66o78-102i164-188o208-227i252-272o278-298i); antiSMASH:Cluster_4.12 AKAW2_40883A COG:I; EggNog:ENOG410QD7V; InterPro:IPR013968,IPR023213,IPR020806,IPR001242, IPR000873,IPR009081,IPR029063,IPR036736,IPR036291, IPR013217,IPR042099; PFAM:PF00550,PF00668,PF13489,PF01209,PF13847, PF00501,PF13649,PF08659,PF00106,PF08242,PF08241; SMCOG1127:condensation domain-containing protein; antiSMASH:Cluster_4.12; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0031177 - phosphopantetheine binding [Evidence IEA] AKAW2_40884A COG:I; EggNog:ENOG410PIJA; InterPro:IPR016036,IPR016035,IPR001227,IPR014043, IPR018201,IPR016039,IPR032821,IPR020807,IPR042104, IPR014030,IPR014031,IPR020841; PFAM:PF16197,PF14765,PF00109,PF02801,PF00698; SMCOG1093:Beta-ketoacyl synthase; antiSMASH:Cluster_4.12; go_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein] synthase activity [Evidence IEA]; go_function: GO:0016740 - transferase activity [Evidence IEA]; go_function: GO:0016746 - transferase activity, transferring acyl groups [Evidence IEA]; go_process: GO:0006633 - fatty acid biosynthetic process [Evidence IEA] AKAW2_40885S COG:C; EggNog:ENOG410PMCP; InterPro:IPR013154,IPR013149,IPR036291,IPR011032, IPR020843; PFAM:PF00107,PF08240; SMCOG1028:crotonyl-CoA reductase / alcohol dehydrogenase; antiSMASH:Cluster_4.12; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_40886S COG:S; EggNog:ENOG410PR5Z; InterPro:IPR023213,IPR010828; PFAM:PF07247; antiSMASH:Cluster_4.12 AKAW2_40887A COG:D; EggNog:ENOG410PJFW; InterPro:IPR007632; PFAM:PF04547; TransMembrane:8 (i182-205o211-232i286-307o327-348i369-391o519-539i567- 588o600-618i); antiSMASH:Cluster_4.12 AKAW2_40888S COG:I; EggNog:ENOG410PP86; InterPro:IPR025714,IPR029063; PFAM:PF13649,PF13489,PF05401,PF01209,PF08242, PF08241,PF07021,PF13847; SMCOG1089:methyltransferase; antiSMASH:Cluster_4.12 AKAW2_40889A COG:S; EggNog:ENOG410Q0RC; InterPro:IPR036020,IPR001202; TransMembrane:1 (i234-252o); antiSMASH:Cluster_4.12; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_40890A COG:P; EggNog:ENOG410PGJU; InterPro:IPR004837; PFAM:PF01699; TransMembrane:7 (i21-40o60-77i375-398o410-433i440-465o471-494i501-521o); antiSMASH:Cluster_4.13; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_40891A COG:P; EggNog:ENOG410PGJU; TransMembrane:3 (i81-103o109-128i140-159o); antiSMASH:Cluster_4.13 AKAW2_40892S COG:S; EggNog:ENOG410PJ2B; InterPro:IPR018823,IPR018820; PFAM:PF13515,PF10337,PF10334; TransMembrane:12 (i35-54o60-78i90-113o133-151i163-184o196-215i604-621o627- 643i655-676o682-699i704-723o743-769i); antiSMASH:Cluster_4.14 AKAW2_40893A CAZy:AA7; COG:C; EggNog:ENOG410PUYJ; InterPro:IPR006094,IPR036318,IPR016166,IPR012951; PFAM:PF08031,PF01565; SECRETED:SignalP(1-18); SMCOG1138:FAD linked oxidase domain protein; antiSMASH:Cluster_4.14; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_function: GO:0071949 - FAD binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_40894S COG:S; EggNog:ENOG410Q2JS; InterPro:IPR008949; PFAM:PF19086; SMCOG1052:Terpene synthase/cyclase metal-binding domain protein; antiSMASH:Cluster_4.14 AKAW2_40895A CAZy:CE2; COG:S; EggNog:ENOG410PG2T; InterPro:IPR013830,IPR036514,IPR037461; PFAM:PF13472; antiSMASH:Cluster_4.14; go_function: GO:0052689 - carboxylic ester hydrolase activity [Evidence IEA] AKAW2_40896S COG:Q; EggNog:ENOG410PMC8; InterPro:IPR006680,IPR011059,IPR032466; MEROPS:MER0005900; PFAM:PF01979; antiSMASH:Cluster_4.14; go_function: GO:0016787 - hydrolase activity [Evidence IEA]; go_function: GO:0016810 - hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [Evidence IEA] AKAW2_40897A COG:S; EggNog:ENOG410PZ5Z; TransMembrane:3 (o86-110i122-141o153-172i); antiSMASH:Cluster_4.14 AKAW2_40898A COG:S; EggNog:ENOG410PRQK; InterPro:IPR021054; PFAM:PF12296; SECRETED:SignalP(1-17); antiSMASH:Cluster_4.14 AKAW2_40899S antiSMASH:Cluster_4.14 AKAW2_40900S COG:L; EggNog:ENOG410PIMX; InterPro:IPR041677,IPR000967,IPR027417,IPR041679; PFAM:PF13086,PF13087; go_component: GO:0005634 - nucleus [Evidence IEA]; go_function: GO:0003700 - DNA-binding transcription factor activity [Evidence IEA]; go_function: GO:0004386 - helicase activity [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_40902S InterPro:IPR018247,IPR002048,IPR011992; go_function: GO:0005509 - calcium ion binding [Evidence IEA] AKAW2_40903S COG:E,O; EggNog:ENOG410PG21; InterPro:IPR001563,IPR029058; MEROPS:MER0001944; SECRETED:SignalP(1-18); go_function: GO:0004185 - serine-type carboxypeptidase activity [Evidence IEA]; go_process: GO:0006508 - proteolysis [Evidence IEA] AKAW2_40904S COG:E,O; EggNog:ENOG410PG21; InterPro:IPR018202,IPR001563,IPR033124,IPR029058; MEROPS:MER0001944; PFAM:PF00450; go_function: GO:0004185 - serine-type carboxypeptidase activity [Evidence IEA]; go_process: GO:0006508 - proteolysis [Evidence IEA] AKAW2_40905S COG:Q; EggNog:ENOG410PUI4; InterPro:IPR013154,IPR013149,IPR036291,IPR011032, IPR020843; PFAM:PF00107,PF08240,PF13602; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_40906A CAZy:CE5; COG:G; EggNog:ENOG410PMSQ; InterPro:IPR011150,IPR043580,IPR029058,IPR000675; PFAM:PF01083; SECRETED:SignalP(1-19); go_component: GO:0005576 - extracellular region [Evidence IEA]; go_function: GO:0016787 - hydrolase activity [Evidence IEA]; go_function: GO:0050525 - cutinase activity [Evidence IEA] AKAW2_40907A CAZy:GT20; COG:H; EggNog:ENOG410QEIQ; InterPro:IPR001830; PFAM:PF00982; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_process: GO:0005992 - trehalose biosynthetic process [Evidence IEA] AKAW2_40908A COG:S; EggNog:ENOG410PQ9B; InterPro:IPR018767,IPR040202; PFAM:PF10104; TransMembrane:2 (o230-252i338-357o); go_component: GO:0005635 - nuclear envelope [Evidence IEA]; go_component: GO:0031965 - nuclear membrane [Evidence IEA]; go_process: GO:0006998 - nuclear envelope organization [Evidence IEA]; go_process: GO:0055088 - lipid homeostasis [Evidence IEA] AKAW2_40909A COG:S; EggNog:ENOG410PZ5W AKAW2_40910A BUSCO:EOG092658NW; COG:A; EggNog:ENOG410PPQU; InterPro:IPR018609; PFAM:PF09736 AKAW2_40911S COG:L; EggNog:ENOG410QD6E; InterPro:IPR014048,IPR036388,IPR036217; PFAM:PF01035; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_process: GO:0006281 - DNA repair [Evidence IEA] AKAW2_40912A COG:T; EggNog:ENOG410PFP2; InterPro:IPR017441,IPR008271,IPR000719,IPR011009; PFAM:PF07714,PF00069; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_40914S COG:S; EggNog:ENOG410PJ64; InterPro:IPR004843,IPR029052; PFAM:PF00149; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_40913A COG:C; EggNog:ENOG410PJ3B; InterPro:IPR037458,IPR001199,IPR037396,IPR008259, IPR013785,IPR036400,IPR000262,IPR018506; PFAM:PF00173,PF01070; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_40915A COG:U; EggNog:ENOG410PKHV; InterPro:IPR005225,IPR001806,IPR027417; PFAM:PF00025,PF08477,PF00071,PF01926; go_function: GO:0003924 - GTPase activity [Evidence IEA]; go_function: GO:0005525 - GTP binding [Evidence IEA] AKAW2_40916S COG:S; EggNog:ENOG410PW2Y; InterPro:IPR021838; PFAM:PF11913 AKAW2_40917A COG:C,H; EggNog:ENOG410PKIW; InterPro:IPR036188,IPR002938; PFAM:PF01494; TransMembrane:1 (n12-22c27/28o447-471i); go_function: GO:0071949 - FAD binding [Evidence IEA] AKAW2_40918A COG:S; EggNog:ENOG410PX40 AKAW2_40920A COG:S; EggNog:ENOG410PNPR; InterPro:IPR024624,IPR012349; PFAM:PF12766; go_function: GO:0010181 - FMN binding [Evidence IEA] AKAW2_40921A COG:A; EggNog:ENOG410PKII; InterPro:IPR032675; PFAM:PF14580 AKAW2_40922A COG:F; EggNog:ENOG410PH76; InterPro:IPR000407; PFAM:PF01150; TransMembrane:1 (o418-437i); go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_40923A COG:P; EggNog:ENOG410PGM6; InterPro:IPR024041,IPR018047,IPR001905,IPR029020; PFAM:PF00909; TransMembrane:11 (o32-56i63-83o117-140i152-172o192-209i221-241o253-274i283- 302o308-328i340-359o387-408i); go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0008519 - ammonium transmembrane transporter activity [Evidence IEA]; go_process: GO:0015696 - ammonium transport [Evidence IEA]; go_process: GO:0072488 - ammonium transmembrane transport [Evidence IEA] AKAW2_40925S COG:S; EggNog:ENOG410Q2FZ; InterPro:IPR036864,IPR021858,IPR001138; PFAM:PF00172; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_40926A SECRETED:SignalP(1-24) AKAW2_40927S COG:S; EggNog:ENOG410PKZZ AKAW2_40928A COG:G; EggNog:ENOG410PKFT; InterPro:IPR023271,IPR034294,IPR000425; PFAM:PF00230; TransMembrane:6 (i39-59o79-98i125-146o166-185i192-212o237-257i); go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0015267 - channel activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_40929S COG:C; EggNog:ENOG410PJPT; InterPro:IPR012292,IPR000971,IPR009050,IPR017927, IPR023950,IPR001433,IPR017938,IPR039261; PFAM:PF00042,PF00175; TransMembrane:1 (o276-296i); go_function: GO:0008941 - nitric oxide dioxygenase activity [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0019825 - oxygen binding [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_function: GO:0071949 - FAD binding [Evidence IEA]; go_process: GO:0051409 - response to nitrosative stress [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_40930A COG:O; EggNog:ENOG410PI5I; InterPro:IPR023828,IPR000209,IPR030400,IPR015366, IPR036852; MEROPS:MER0078639; PFAM:PF09286,PF00082; SECRETED:SignalP(1-26); go_function: GO:0004252 - serine-type endopeptidase activity [Evidence IEA]; go_function: GO:0008236 - serine-type peptidase activity [Evidence IEA]; go_process: GO:0006508 - proteolysis [Evidence IEA] AKAW2_40931S COG:S; EggNog:ENOG410PKGE; InterPro:IPR011009,IPR002575; PFAM:PF01636 AKAW2_40932S COG:S; EggNog:ENOG410PK6B; InterPro:IPR002893; PFAM:PF01753 AKAW2_40933A COG:L; EggNog:ENOG410Q2Y9; InterPro:IPR011598,IPR036638; PFAM:PF00010; go_function: GO:0046983 - protein dimerization activity [Evidence IEA] AKAW2_40934A COG:G,M; EggNog:ENOG410PKT0; InterPro:IPR036291,IPR016040; PFAM:PF13460,PF05368 AKAW2_40935A COG:S; EggNog:ENOG410PUZI; InterPro:IPR011009,IPR002575; PFAM:PF01636 AKAW2_40936S COG:E; EggNog:ENOG410PWKQ; InterPro:IPR002293; PFAM:PF00324,PF13520; TransMembrane:12 (i40-59o71-93i127-150o170-188i200-222o248-272i284-310o330- 354i389-407o413-436i448-472o484-503i); go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_40937S COG:Q; EggNog:ENOG410PVXX; InterPro:IPR034001,IPR043926,IPR027417,IPR003593, IPR010929,IPR017871,IPR034003,IPR003439,IPR013525; PFAM:PF01061,PF06422,PF00005,PF12698; TransMembrane:13 (o412-433i440-456o485-511i523-544o556-574i659-681o1058- 1077i1089-1108o1128-1161i1173-1193o1199-1221i1233- 1253o1327-1346i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA]; go_function: GO:0042626 - ATPase-coupled transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_40938A COG:S; EggNog:ENOG410Q1VC; TransMembrane:6 (o28-52i59-79o91-112i124-141o161-184i204-228o) AKAW2_40940S COG:E; EggNog:ENOG410PGGM; InterPro:IPR002629,IPR038071; PFAM:PF01717; go_function: GO:0003871 - 5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0009086 - methionine biosynthetic process [Evidence IEA] AKAW2_40941S COG:G; EggNog:ENOG410PFT9; InterPro:IPR002828,IPR036523; PFAM:PF01975; SECRETED:SignalP(1-17); go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_40942S COG:S; EggNog:ENOG410PNF2; InterPro:IPR008701; PFAM:PF05630; SECRETED:SignalP(1-19) AKAW2_40943A CAZy:AA9; COG:G; EggNog:ENOG410PNFI; InterPro:IPR000254,IPR035971,IPR005103; PFAM:PF00734,PF03443; SECRETED:SignalP(1-21); go_component: GO:0005576 - extracellular region [Evidence IEA]; go_function: GO:0030248 - cellulose binding [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_40944A COG:S; EggNog:ENOG410Q1Z5; InterPro:IPR023213 AKAW2_40945S COG:G; EggNog:ENOG410PHGF; InterPro:IPR005829,IPR005828,IPR003663,IPR036259, IPR020846; PFAM:PF00083,PF07690; TransMembrane:9 (i122-140o165-184i196-217o223-242i254-276o288-309i380- 399o411-434i441-463o); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_40946S COG:G; EggNog:ENOG410PHGF; InterPro:IPR005828,IPR036259; TransMembrane:1 (o32-50i); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_40947S COG:S; EggNog:ENOG410PRUM AKAW2_40948S COG:E; EggNog:ENOG410Q1Y5; InterPro:IPR013057; PFAM:PF01490; TransMembrane:11 (i68-87o93-114i142-165o171-192i199-222o242-263i275- 297o317-336i357-378o390-411i423-446o) AKAW2_40949S COG:G; EggNog:ENOG410PFEN; InterPro:IPR005829,IPR005828,IPR003663,IPR036259, IPR020846; PFAM:PF00083,PF07690; TransMembrane:11 (o15-32i62-85o91-109i150-170o182-204i275-298o310-334i341- 365o371-395i407-430o436-456i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_40950S COG:E,J; EggNog:ENOG410PGP5; InterPro:IPR027417,IPR003439; go_function: GO:0005524 - ATP binding [Evidence IEA] AKAW2_40951S COG:E,J; EggNog:ENOG410PGP5; InterPro:IPR027417,IPR003593,IPR003439; PFAM:PF00005; go_function: GO:0005524 - ATP binding [Evidence IEA] AKAW2_40952A COG:G; EggNog:ENOG410Q1WI; InterPro:IPR002594,IPR013319,IPR013320; PFAM:PF01670; SECRETED:SignalP(1-16); go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_function: GO:0008810 - cellulase activity [Evidence IEA]; go_process: GO:0000272 - polysaccharide catabolic process [Evidence IEA] AKAW2_40953A SECRETED:SignalP(1-19) AKAW2_40954S COG:S; EggNog:ENOG410PV2P; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_40955A COG:S; EggNog:ENOG410PHAM; InterPro:IPR036412,IPR027417,IPR023214 AKAW2_40956S COG:S; EggNog:ENOG410PVG1 AKAW2_40957A CAZy:GH93; COG:S; EggNog:ENOG410PNE0; InterPro:IPR036278 AKAW2_40958S COG:S; EggNog:ENOG410PVUN; InterPro:IPR011009 AKAW2_40959S COG:S; EggNog:ENOG410PVUN AKAW2_40960S COG:T; EggNog:ENOG410Q5KN AKAW2_40963S COG:S; EggNog:ENOG410PQBQ; InterPro:IPR021833; PFAM:PF11905 AKAW2_40964S COG:S; EggNog:ENOG410PRXS; InterPro:IPR011008,IPR009799; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA] AKAW2_40966S COG:F,Q; EggNog:ENOG410PM13; InterPro:IPR011059,IPR006680,IPR032466; MEROPS:MER0033186; PFAM:PF01979; go_function: GO:0016787 - hydrolase activity [Evidence IEA]; go_function: GO:0016810 - hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [Evidence IEA] AKAW2_40967A COG:C; EggNog:ENOG410PFYI; InterPro:IPR015590,IPR044086,IPR029510,IPR016161, IPR016162,IPR016163; PFAM:PF00171; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0016620 - oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_40968S COG:G; EggNog:ENOG410PF97; InterPro:IPR005828,IPR003663,IPR036259,IPR020846; PFAM:PF00083,PF07690; TransMembrane:11 (o100-120i127-146o152-173i185-205o225-245i304-327o339- 362i369-391o403-424i436-458o470-489i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_40969S COG:C; EggNog:ENOG410PGVS; InterPro:IPR041694,IPR013149,IPR036291,IPR011032, IPR020843; PFAM:PF00107,PF13602,PF16884; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_40970A COG:S; EggNog:ENOG410PN1X; InterPro:IPR038697,IPR006593,IPR005018,IPR015920; PFAM:PF16010; SECRETED:SignalP(1-16); TransMembrane:3 (n3-11c16/17o257-279i300-319o331-350i) AKAW2_40971S COG:S; EggNog:ENOG410PX61; InterPro:IPR029032 AKAW2_40972A COG:G; EggNog:ENOG410QDJA; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i85-110o122-140i152-169o181-202i214-235o247-266i314- 339o351-371i378-398o410-430i442-463o469-495i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_40973S CAZy:GH105; COG:S; EggNog:ENOG410PGQV; InterPro:IPR008928,IPR012341,IPR010905; PFAM:PF07470; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_40974A COG:S; EggNog:ENOG410PYZ0; InterPro:IPR036047; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_40975A CAZy:AA3; COG:E; EggNog:ENOG410PKC0; InterPro:IPR012132,IPR036188,IPR000172,IPR007867; PFAM:PF05199,PF00732; go_function: GO:0016614 - oxidoreductase activity, acting on CH-OH group of donors [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_40976S COG:S; EggNog:ENOG410PMRM; InterPro:IPR006094,IPR036318,IPR016166,IPR012951; PFAM:PF08031,PF01565; SECRETED:SignalP(1-18); go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_function: GO:0071949 - FAD binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_40977S COG:S; EggNog:ENOG410PNVX; TransMembrane:5 (i25-49o55-87i96-116o136-154i175-197o) AKAW2_40978S COG:T; EggNog:ENOG410QDW2; InterPro:IPR001789,IPR001294,IPR003594,IPR003661, IPR016132,IPR036890,IPR013515,IPR036097,IPR043150, IPR011006,IPR003018,IPR013654,IPR029016,IPR035965, IPR005467; PFAM:PF00360,PF00072,PF00512,PF01590,PF08446, PF02518; go_function: GO:0000155 - phosphorelay sensor kinase activity [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0000160 - phosphorelay signal transduction system [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA]; go_process: GO:0007165 - signal transduction [Evidence IEA]; go_process: GO:0009584 - detection of visible light [Evidence IEA]; go_process: GO:0018298 - protein-chromophore linkage [Evidence IEA] AKAW2_40979A TransMembrane:3 (o22-48i69-93o162-187i) AKAW2_40981A COG:S; EggNog:ENOG410PTZ3; SECRETED:SignalP(1-18) AKAW2_40982S COG:S; EggNog:ENOG410PK1Q; InterPro:IPR019273,IPR040115; PFAM:PF10058; TransMembrane:2 (i47-69o75-95i); go_process: GO:0071786 - endoplasmic reticulum tubular network organization [Evidence IEA] AKAW2_40983A COG:L; EggNog:ENOG410Q18B; InterPro:IPR027417,IPR038248,IPR005034,IPR036389, IPR000999,IPR001650,IPR014001,IPR011545; PFAM:PF03368,PF00270,PF00271,PF00636,PF04851, PF14622; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0004525 - ribonuclease III activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016891 - endoribonuclease activity, producing 5'-phosphomonoesters [Evidence IEA]; go_process: GO:0006396 - RNA processing [Evidence IEA] AKAW2_40984A COG:K; EggNog:ENOG410PRVF; InterPro:IPR004827; PFAM:PF00170; go_function: GO:0003700 - DNA-binding transcription factor activity [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_40985A COG:D; EggNog:ENOG410PINZ; InterPro:IPR007632; PFAM:PF04547; TransMembrane:8 (i64-84o90-114i168-195o207-233i254-275o317-338i453- 478o490-511i) AKAW2_40986A COG:E; EggNog:ENOG410QEC3; InterPro:IPR016181,IPR000182; PFAM:PF13508,PF13673,PF08445,PF00583; go_function: GO:0008080 - N-acetyltransferase activity [Evidence IEA] AKAW2_40987A COG:U; EggNog:ENOG410PKVU; InterPro:IPR000237; PFAM:PF01465 AKAW2_40988S BUSCO:EOG092603EH; COG:I; EggNog:ENOG410PFPD; InterPro:IPR016035,IPR002641,IPR000595,IPR018490, IPR014710; PFAM:PF00027; TransMembrane:3 (i41-59o79-99i120-142o); go_process: GO:0006629 - lipid metabolic process [Evidence IEA] AKAW2_40989S COG:S; EggNog:ENOG410PW66; InterPro:IPR021838; PFAM:PF11913; TransMembrane:1 (o14-35i) AKAW2_40990S COG:C; EggNog:ENOG410PGIJ; InterPro:IPR006094,IPR036318,IPR016166,IPR012951; PFAM:PF08031,PF01565; SECRETED:SignalP(1-21); go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_function: GO:0071949 - FAD binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_40991A COG:S; EggNog:ENOG410PS8N; InterPro:IPR008253; PFAM:PF01284; TransMembrane:4 (i12-33o45-65i72-92o118-141i); go_component: GO:0016020 - membrane [Evidence IEA] AKAW2_40992S COG:S; EggNog:ENOG410PGHH; InterPro:IPR022812,IPR027417; PFAM:PF00350,PF01926 AKAW2_40993A COG:G; EggNog:ENOG410PKMW; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:10 (i7-25o31-50i62-82o94-115i146-168o188-205i212-231o237- 260i272-296o302-320i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_40994A COG:S; EggNog:ENOG410PPCQ; InterPro:IPR029675; PFAM:PF04666; TransMembrane:3 (o20-43i266-284o296-317i); go_component: GO:0000139 - Golgi membrane [Evidence IEA]; go_function: GO:0016757 - transferase activity, transferring glycosyl groups [Evidence IEA]; go_process: GO:0006506 - GPI anchor biosynthetic process [Evidence IEA] AKAW2_40995A COG:Q; EggNog:ENOG410PW4T; InterPro:IPR036396,IPR001128,IPR017972,IPR002401; PFAM:PF00067; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_40996S COG:S; EggNog:ENOG410PWSV; TransMembrane:7 (o6-32i44-65o99-122i134-161o190-210i222-248o260-280i) AKAW2_40998S COG:S; EggNog:ENOG410PRAE; InterPro:IPR021765; PFAM:PF11807; TransMembrane:1 (o41-59i); go_process: GO:0043386 - mycotoxin biosynthetic process [Evidence IEA] AKAW2_40997A SECRETED:SignalP(1-17) AKAW2_40999A BUSCO:EOG09260QNB; COG:Z; EggNog:ENOG410PH0K; InterPro:IPR027664,IPR004000,IPR043129; PFAM:PF00022 AKAW2_41000A COG:D; EggNog:ENOG410PQR9; InterPro:IPR013959; PFAM:PF08650; go_component: GO:0042729 - DASH complex [Evidence IEA]; go_component: GO:0072686 - mitotic spindle [Evidence IEA]; go_process: GO:0008608 - attachment of spindle microtubules to kinetochore [Evidence IEA] AKAW2_41001S BUSCO:EOG09264I14; COG:S; EggNog:ENOG410PNIM; InterPro:IPR013272,IPR029525; PFAM:PF08265; go_component: GO:0031011 - Ino80 complex [Evidence IEA]; go_process: GO:0006338 - chromatin remodeling [Evidence IEA] AKAW2_41002S COG:U; EggNog:ENOG410PPQI; InterPro:IPR007305; PFAM:PF04178; TransMembrane:4 (i12-32o38-59i71-91o97-117i); go_process: GO:0016192 - vesicle-mediated transport [Evidence IEA] AKAW2_41003A COG:Z; EggNog:ENOG410PQR4; InterPro:IPR036140,IPR005455; PFAM:PF00235; go_function: GO:0003779 - actin binding [Evidence IEA] AKAW2_41004S COG:S; EggNog:ENOG410PT9N AKAW2_41005A COG:A; EggNog:ENOG410PGAG; InterPro:IPR014756,IPR004179,IPR027417,IPR003593, IPR035892,IPR001650,IPR036390,IPR014001,IPR011545; PFAM:PF02889,PF00271,PF04851,PF00270; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA] AKAW2_41006A COG:T; EggNog:ENOG410PGZE; InterPro:IPR008984,IPR000253; PFAM:PF00498; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_41007S COG:O; EggNog:ENOG410PPJG; InterPro:IPR001623,IPR036869,IPR018253; TransMembrane:1 (n7-17c23/24o189-208i) AKAW2_41008S COG:I; EggNog:ENOG410PIK8; InterPro:IPR042098,IPR003819; PFAM:PF08943; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_41009S COG:S; EggNog:ENOG410PIMZ; InterPro:IPR042099 AKAW2_41010A COG:I; EggNog:ENOG410PK4F; InterPro:IPR006091,IPR009075,IPR013786,IPR009100, IPR036250,IPR037069; PFAM:PF02770,PF00441,PF02771,PF08028; go_function: GO:0016627 - oxidoreductase activity, acting on the CH-CH group of donors [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_41011A COG:S; EggNog:ENOG410Q2YD; InterPro:IPR038656,IPR000250,IPR013320; MEROPS:MER0001321; PFAM:PF01828; go_function: GO:0004190 - aspartic-type endopeptidase activity [Evidence IEA]; go_process: GO:0006508 - proteolysis [Evidence IEA] AKAW2_41012A BUSCO:EOG09263IT0; COG:S; EggNog:ENOG410PFA7; InterPro:IPR026113,IPR029063,IPR013217; PFAM:PF13649,PF13489,PF01209,PF08242,PF08241, PF13847 AKAW2_41013A COG:E; EggNog:ENOG410PFSR; InterPro:IPR004404,IPR000581,IPR037237,IPR042096, IPR020558; PFAM:PF00920; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0004160 - dihydroxy-acid dehydratase activity [Evidence IEA]; go_process: GO:0009082 - branched-chain amino acid biosynthetic process [Evidence IEA] AKAW2_41014S COG:Q; EggNog:ENOG410PH0S; InterPro:IPR017871,IPR027417,IPR003593,IPR011527, IPR003439,IPR036640; PFAM:PF00005,PF00664; TransMembrane:15 (o12-32i79-100o106-130i142-163o175-194i285-304o324- 349i422-441o447-464i518-541o936-954i998-1024o1088- 1113i1183-1205o1211-1231i); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA]; go_function: GO:0042626 - ATPase-coupled transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_41015S COG:S; EggNog:ENOG410PRCU; InterPro:IPR021833; PFAM:PF11905 AKAW2_41016A COG:K; EggNog:ENOG410PUUR; InterPro:IPR023209,IPR006076; PFAM:PF01266; go_function: GO:0003884 - D-amino-acid oxidase activity [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0071949 - FAD binding [Evidence IEA]; go_process: GO:0046416 - D-amino acid metabolic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_41017A COG:S; EggNog:ENOG410PIY8; InterPro:IPR021889; PFAM:PF12006 AKAW2_41018A COG:C,H; EggNog:ENOG410PG88; InterPro:IPR036188,IPR002938; PFAM:PF01494; go_function: GO:0071949 - FAD binding [Evidence IEA] AKAW2_41019S COG:I; EggNog:ENOG410PW7Y; InterPro:IPR002123; PFAM:PF01553; TransMembrane:3 (o6-26i466-490o510-536i); go_function: GO:0016746 - transferase activity, transferring acyl groups [Evidence IEA] AKAW2_41020A COG:F; EggNog:ENOG410PI1G; InterPro:IPR002195,IPR011059,IPR032466,IPR006680, IPR017593; MEROPS:MER0005767; PFAM:PF01979; TransMembrane:1 (o365-383i); go_function: GO:0004038 - allantoinase activity [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_function: GO:0016787 - hydrolase activity [Evidence IEA]; go_function: GO:0016810 - hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [Evidence IEA]; go_function: GO:0016812 - hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides [Evidence IEA]; go_function: GO:0050897 - cobalt ion binding [Evidence IEA]; go_process: GO:0000256 - allantoin catabolic process [Evidence IEA] AKAW2_41021S COG:E; EggNog:ENOG410PM5M; InterPro:IPR014746,IPR008146,IPR006680,IPR032466; PFAM:PF00120; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0004356 - glutamate-ammonia ligase activity [Evidence IEA]; go_function: GO:0016787 - hydrolase activity [Evidence IEA]; go_process: GO:0006807 - nitrogen compound metabolic process [Evidence IEA] AKAW2_41022S BUSCO:EOG09263POH; COG:E; EggNog:ENOG410PH0Z; InterPro:IPR002292,IPR006132,IPR006130,IPR006131, IPR036901; PFAM:PF02729,PF00185; go_function: GO:0016597 - amino acid binding [Evidence IEA]; go_function: GO:0016743 - carboxyl- or carbamoyltransferase activity [Evidence IEA]; go_process: GO:0006520 - cellular amino acid metabolic process [Evidence IEA] AKAW2_41023A COG:O; EggNog:ENOG410PFM3; InterPro:IPR036249,IPR009737; PFAM:PF06999 AKAW2_41024A BUSCO:EOG09263IMF; COG:O; EggNog:ENOG410PI47; InterPro:IPR003675,IPR039731; MEROPS:MER0004246; PFAM:PF02517; TransMembrane:7 (o28-46i67-86o106-126i186-203o215-237i244-264o297-317i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0030176 - integral component of endoplasmic reticulum membrane [Evidence IEA]; go_function: GO:0004222 - metalloendopeptidase activity [Evidence IEA]; go_process: GO:0071586 - CAAX-box protein processing [Evidence IEA] AKAW2_41025S COG:Q; EggNog:ENOG410PI3E; InterPro:IPR020946,IPR036188; PFAM:PF13450; go_function: GO:0004499 - N,N-dimethylaniline monooxygenase activity [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_function: GO:0050661 - NADP binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_41026A COG:S; EggNog:ENOG410PNY5; InterPro:IPR001138,IPR036864; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_41027A COG:Q; EggNog:ENOG410PM4N; InterPro:IPR036291,IPR002347; PFAM:PF08659,PF00106; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_41028A COG:S; EggNog:ENOG410PR1Y; InterPro:IPR011990,IPR001810,IPR019734,IPR013105, IPR036047,IPR032675,IPR013026; PFAM:PF07719,PF00646,PF12937; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_41029S COG:S; EggNog:ENOG410PFHP; InterPro:IPR021622; PFAM:PF11559 AKAW2_41032A COG:G; EggNog:ENOG410PFPE; InterPro:IPR029061,IPR020826,IPR033248,IPR033247, IPR009014,IPR005474,IPR005475; PFAM:PF13292,PF02779,PF00456; go_function: GO:0003824 - catalytic activity [Evidence IEA] AKAW2_41033S COG:Q; EggNog:ENOG410PJR0; InterPro:IPR013154,IPR013149,IPR002328,IPR036291, IPR011032,IPR020843; PFAM:PF00107,PF08240; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_41034S CAZy:GH76; COG:G; EggNog:ENOG410PFRH; InterPro:IPR014480,IPR008928,IPR005198; PFAM:PF03663; TransMembrane:2 (n7-18c25/26o312-329i435-455o); go_function: GO:0008496 - mannan endo-1,6-alpha-mannosidase activity [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA]; go_process: GO:0016052 - carbohydrate catabolic process [Evidence IEA] AKAW2_41035A COG:S; EggNog:ENOG410PU7B; TransMembrane:7 (o12-37i49-74o94-116i128-149o180-198i205-229o249-267i) AKAW2_41036S COG:S; EggNog:ENOG410PY53; InterPro:IPR036864,IPR021858,IPR001138; PFAM:PF11951; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_41037A COG:G; EggNog:ENOG410QDHG; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:13 (o38-56i63-83o89-106i118-136o142-162i174-193o205-225i274- 298o310-331i338-355o367-387i399-419o431-452i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_41038S COG:Q; EggNog:ENOG410PMC8; InterPro:IPR006680,IPR011059,IPR032466; MEROPS:MER0005900; PFAM:PF01979; go_function: GO:0016787 - hydrolase activity [Evidence IEA]; go_function: GO:0016810 - hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [Evidence IEA] AKAW2_41039S COG:Q; EggNog:ENOG410PUNY; InterPro:IPR034001,IPR043926,IPR027417,IPR003593, IPR010929,IPR017871,IPR034003,IPR003439,IPR013525; PFAM:PF01061,PF00005,PF06422; TransMembrane:12 (i470-491o503-521i542-571o577-598i722-743o1140-1157i1169- 1189o1209-1237i1249-1271o1277-1297i1309-1329o1403-1421i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA]; go_function: GO:0042626 - ATPase-coupled transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_41040A COG:P; EggNog:ENOG410PGTE; InterPro:IPR031563; PFAM:PF16983; TransMembrane:10 (o20-41i53-73o93-113i125-146o158-175i180-199o265-285i297- 320o332-353i389-419o); go_function: GO:0015098 - molybdate ion transmembrane transporter activity [Evidence IEA]; go_process: GO:0015689 - molybdate ion transport [Evidence IEA] AKAW2_41041A COG:S; EggNog:ENOG410PPNU; InterPro:IPR022226; PFAM:PF12572 AKAW2_41042A COG:S; EggNog:ENOG410PFWC; InterPro:IPR018830; PFAM:PF10361; TransMembrane:7 (o86-107i128-148o160-182i212-237o257-277i297-321o341- 364i) AKAW2_41043S COG:Q; EggNog:ENOG410PJDN; InterPro:IPR001128,IPR002401,IPR036396; PFAM:PF00067; TransMembrane:1 (o6-27i); go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_41044S BUSCO:EOG09261BPJ; COG:J; EggNog:ENOG410QDBB; InterPro:IPR001313,IPR016024,IPR011989,IPR040000; PFAM:PF00806; go_function: GO:0003723 - RNA binding [Evidence IEA] AKAW2_41045A COG:A; EggNog:ENOG410PFJ5; InterPro:IPR027417,IPR001650,IPR014001,IPR011545, IPR000629; PFAM:PF04851,PF00270,PF00271; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA] AKAW2_41046A COG:S; EggNog:ENOG410PUFQ; InterPro:IPR036188,IPR002938; PFAM:PF01494; go_function: GO:0071949 - FAD binding [Evidence IEA] AKAW2_41047A COG:S; EggNog:ENOG410PH62; InterPro:IPR003864,IPR027815,IPR032880,IPR022257; PFAM:PF12621,PF14703,PF02714,PF13967; TransMembrane:11 (o32-53i112-131o158-180i414-441o461-485i506-534o554- 580i601-623o629-647i668-689o695-715i); go_component: GO:0016020 - membrane [Evidence IEA] AKAW2_41048A COG:S; EggNog:ENOG410PVY1 AKAW2_41049S BUSCO:EOG09260JT9; COG:L; EggNog:ENOG410PG2R; InterPro:IPR027417,IPR027925,IPR041562,IPR001208, IPR033762,IPR041024,IPR031327,IPR012340,IPR008049, IPR018525; PFAM:PF00493,PF18263,PF17207,PF17855,PF14551; go_component: GO:0005634 - nucleus [Evidence IEA]; go_component: GO:0042555 - MCM complex [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0003678 - DNA helicase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006260 - DNA replication [Evidence IEA]; go_process: GO:0006270 - DNA replication initiation [Evidence IEA]; go_process: GO:0032508 - DNA duplex unwinding [Evidence IEA] AKAW2_41050S COG:L; EggNog:ENOG410QDFK; InterPro:IPR027417,IPR000330,IPR038718; go_function: GO:0005524 - ATP binding [Evidence IEA] AKAW2_41051S COG:L; EggNog:ENOG410QDFK; InterPro:IPR001841,IPR017907,IPR027417,IPR001650, IPR013083; PFAM:PF13920,PF00271,PF00097 AKAW2_41053A COG:S; EggNog:ENOG410PM88 AKAW2_41054A BUSCO:EOG0926025H; COG:S; EggNog:ENOG410QDCA; InterPro:IPR016024,IPR039844,IPR021714,IPR032436; PFAM:PF11707,PF16201 AKAW2_41055S InterPro:IPR024311; PFAM:PF13924 AKAW2_41056A COG:A; EggNog:ENOG410PGGT; InterPro:IPR011709,IPR027417,IPR022967,IPR003029, IPR014001,IPR007502,IPR002464,IPR001650,IPR012340; PFAM:PF04408,PF07717,PF00575,PF00271; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0004386 - helicase activity [Evidence IEA] AKAW2_41057A BUSCO:EOG092629FB; COG:A; EggNog:ENOG410PIPB; InterPro:IPR027417,IPR014001,IPR001650,IPR022192; PFAM:PF00271,PF12513; go_function: GO:0016817 - hydrolase activity, acting on acid anhydrides [Evidence IEA] AKAW2_41058S BUSCO:EOG09261ZJR; COG:U; EggNog:ENOG410PH9K; InterPro:IPR001619,IPR043127,IPR036045,IPR043154, IPR027482; PFAM:PF00995; go_process: GO:0006904 - vesicle docking involved in exocytosis [Evidence IEA]; go_process: GO:0016192 - vesicle-mediated transport [Evidence IEA] AKAW2_41059A COG:S; EggNog:ENOG410PNZ1; InterPro:IPR000467,IPR039146; PFAM:PF01585; go_function: GO:0003676 - nucleic acid binding [Evidence IEA] AKAW2_41060S COG:Q; EggNog:ENOG410PGQ1; InterPro:IPR036291,IPR002347; PFAM:PF00106; TransMembrane:2 (o20-40i319-341o); go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_41061A COG:M; EggNog:ENOG410PFN4; InterPro:IPR036291,IPR016040,IPR005886; PFAM:PF04321,PF00106,PF01073,PF16363,PF08659, PF01370; go_function: GO:0003978 - UDP-glucose 4-epimerase activity [Evidence IEA]; go_process: GO:0006012 - galactose metabolic process [Evidence IEA] AKAW2_41062A COG:Q; EggNog:ENOG410PKH2; InterPro:IPR001128,IPR002401,IPR036396; PFAM:PF00067; TransMembrane:2 (o6-25i298-320o); go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_41063A COG:Q; EggNog:ENOG410PHJE; InterPro:IPR001128,IPR017972,IPR002401,IPR036396; PFAM:PF00067; TransMembrane:1 (i21-41o); go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_41064A BUSCO:EOG09260S3L; COG:S; EggNog:ENOG410PK3S; InterPro:IPR019167,IPR039900; PFAM:PF09770; go_process: GO:0000290 - deadenylation-dependent decapping of nuclear-transcribed mRNA [Evidence IEA] AKAW2_41065S CAZy:GT15; COG:G; EggNog:ENOG410PG1J; InterPro:IPR029044,IPR002685; PFAM:PF01793; go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0000030 - mannosyltransferase activity [Evidence IEA]; go_process: GO:0006486 - protein glycosylation [Evidence IEA] AKAW2_41066A BUSCO:EOG092653KS; COG:J; EggNog:ENOG410PP82; InterPro:IPR006032,IPR012340,IPR005679; PFAM:PF00164; go_component: GO:0005840 - ribosome [Evidence IEA]; go_component: GO:0015935 - small ribosomal subunit [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_process: GO:0006412 - translation [Evidence IEA] AKAW2_41067S BUSCO:EOG092654XA; COG:O; EggNog:ENOG410PRK2; InterPro:IPR008012; PFAM:PF05348; go_process: GO:0043248 - proteasome assembly [Evidence IEA] AKAW2_41068A COG:S; EggNog:ENOG410PPFQ; InterPro:IPR029071,IPR039540,IPR040015; PFAM:PF13881 AKAW2_41069S COG:S; EggNog:ENOG410PG49; InterPro:IPR014756,IPR014752,IPR011021,IPR011022; PFAM:PF00339,PF02752 AKAW2_41070S COG:G; EggNog:ENOG410PFEN; InterPro:IPR005829,IPR005828,IPR003663,IPR036259, IPR020846; PFAM:PF00083,PF07690; TransMembrane:11 (n14-29c37/38o61-81i88-107o113-130i150-169o181-203i280- 298o310-331i343-361o373-392i404-426o432-453i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_41071S COG:K; EggNog:ENOG410PWM5; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_41072A COG:I; EggNog:ENOG410PJBM; InterPro:IPR013750,IPR035102,IPR016005,IPR006204, IPR036554,IPR020568,IPR014721; PFAM:PF00288,PF08544; go_function: GO:0004631 - phosphomevalonate kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA] AKAW2_41073S COG:S; EggNog:ENOG410PH31; InterPro:IPR002885,IPR011990; PFAM:PF13041,PF12854,PF13812,PF17177,PF01535; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_41074S BUSCO:EOG09264ZXA; COG:H; EggNog:ENOG410PP4Z; InterPro:IPR000659,IPR019576,IPR011576,IPR019740; PFAM:PF10590; go_function: GO:0004733 - pyridoxamine-phosphate oxidase activity [Evidence IEA]; go_function: GO:0010181 - FMN binding [Evidence IEA]; go_function: GO:0016638 - oxidoreductase activity, acting on the CH-NH2 group of donors [Evidence IEA]; go_process: GO:0008615 - pyridoxine biosynthetic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_41075S COG:S; EggNog:ENOG410PPW8; InterPro:IPR000620,IPR039632; PFAM:PF00892; TransMembrane:4 (i29-47o77-102i114-134o140-157i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA] AKAW2_41076A COG:P; EggNog:ENOG410PH9R; InterPro:IPR001807,IPR014743,IPR000644; PFAM:PF00654,PF00571; SECRETED:SignalP(1-22); TransMembrane:7 (n4-17c22/23o32-49i61-85o97-114i135-154o174-195i226- 247o253-274i); go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0005247 - voltage-gated chloride channel activity [Evidence IEA]; go_process: GO:0006821 - chloride transport [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_41077S COG:K; EggNog:ENOG410PPVZ; InterPro:IPR009072,IPR003958; PFAM:PF00808; go_function: GO:0046982 - protein heterodimerization activity [Evidence IEA] AKAW2_41078S BUSCO:EOG09264MIL; COG:C; EggNog:ENOG410PFIA; InterPro:IPR017941,IPR037008,IPR006317,IPR005805, IPR036922,IPR014349,IPR004192; PFAM:PF02921,PF00355; go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0008121 - ubiquinol-cytochrome-c reductase activity [Evidence IEA]; go_function: GO:0051537 - 2 iron, 2 sulfur cluster binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_41079A BUSCO:EOG09264LJU; COG:U; EggNog:ENOG410PGX2; InterPro:IPR008839; PFAM:PF05546; TransMembrane:2 (o299-319i470-492o) AKAW2_41080A COG:S; EggNog:ENOG410PSE0; InterPro:IPR000612; PFAM:PF01679; TransMembrane:2 (o6-26i33-53o); go_component: GO:0016021 - integral component of membrane [Evidence IEA] AKAW2_41082S COG:S; EggNog:ENOG410PHK2; InterPro:IPR036028; TransMembrane:1 (o239-264i); go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_41083S COG:Z; EggNog:ENOG410PQ05; InterPro:IPR029006,IPR017904,IPR002108; PFAM:PF00241; go_component: GO:0015629 - actin cytoskeleton [Evidence IEA]; go_function: GO:0003779 - actin binding [Evidence IEA]; go_process: GO:0030042 - actin filament depolymerization [Evidence IEA] AKAW2_41084S COG:C; EggNog:ENOG410PNPD; InterPro:IPR036639,IPR004203; PFAM:PF02936; TransMembrane:1 (o126-148i); go_function: GO:0004129 - cytochrome-c oxidase activity [Evidence IEA] AKAW2_41085S BUSCO:EOG09261T74; COG:C; EggNog:ENOG410PIAZ; InterPro:IPR027417,IPR024034,IPR003593,IPR005722, IPR036121,IPR004100,IPR020003,IPR000194; PFAM:PF00006,PF02874; go_component: GO:0045261 - proton-transporting ATP synthase complex, catalytic core F(1) [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0046933 - proton-transporting ATP synthase activity, rotational mechanism [Evidence IEA]; go_process: GO:0015986 - ATP synthesis coupled proton transport [Evidence IEA]; go_process: GO:0046034 - ATP metabolic process [Evidence IEA]; go_process: GO:1902600 - proton transmembrane transport [Evidence IEA] AKAW2_41086A CAZy:GH13; COG:G; EggNog:ENOG410PF87; InterPro:IPR006047,IPR037439,IPR014756,IPR017853, IPR006048,IPR013783,IPR013780,IPR004193; PFAM:PF02922,PF02806; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0003844 - 1,4-alpha-glucan branching enzyme activity [Evidence IEA]; go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_function: GO:0043169 - cation binding [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA]; go_process: GO:0005978 - glycogen biosynthetic process [Evidence IEA] AKAW2_41087A CAZy:GH28; COG:G; EggNog:ENOG410PHHF; InterPro:IPR000743,IPR012334,IPR011050; PFAM:PF00295; SECRETED:SignalP(1-21); go_function: GO:0004650 - polygalacturonase activity [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_41088A COG:S; EggNog:ENOG410Q28S; SECRETED:SignalP(1-18) AKAW2_41089A CAZy:GH92; COG:L; EggNog:ENOG410PI20; InterPro:IPR041371,IPR014718,IPR012939,IPR008928, IPR005887; PFAM:PF17678,PF07971; SECRETED:SignalP(1-37); go_function: GO:0030246 - carbohydrate binding [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_41090S COG:G; EggNog:ENOG410Q2RQ; InterPro:IPR005829,IPR005828,IPR003663,IPR036259, IPR020846; PFAM:PF00083,PF07690; TransMembrane:12 (i7-25o64-83i90-109o121-138i150-167o187-204i272-294o314- 332i339-359o371-388i409-427o439-462i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_41091S COG:J; EggNog:ENOG410PIP8; InterPro:IPR023631,IPR036928; SECRETED:SignalP(1-24) AKAW2_41092S COG:J; EggNog:ENOG410PIP8; InterPro:IPR023631,IPR036928 AKAW2_41093S COG:H; EggNog:ENOG410PFVS; InterPro:IPR035985,IPR001763,IPR000594,IPR028885, IPR036873; PFAM:PF00899,PF00581; go_component: GO:0005829 - cytosol [Evidence IEA]; go_function: GO:0004792 - thiosulfate sulfurtransferase activity [Evidence IEA]; go_function: GO:0008641 - ubiquitin-like modifier activating enzyme activity [Evidence IEA]; go_process: GO:0002143 - tRNA wobble position uridine thiolation [Evidence IEA] AKAW2_41094S COG:S; EggNog:ENOG410PJ2B; InterPro:IPR018823,IPR018820; PFAM:PF13515,PF10337,PF10334; TransMembrane:12 (i42-64o70-88i100-120o140-160i172-198o204-223i622-639o645- 662i674-693o699-717i724-741o761-785i) AKAW2_41095S COG:Q; EggNog:ENOG410PNMA; InterPro:IPR036291,IPR002347; PFAM:PF08659,PF00106,PF13561; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_41096S COG:G; EggNog:ENOG410Q2YG; InterPro:IPR020846,IPR036259; TransMembrane:14 (i56-80o100-119i126-146o152-170i182-204o210-230i251- 271o277-296i317-341o347-370i382-403o409-431i452-475o515- 534i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA] AKAW2_41098A CAZy:PL1; COG:G; EggNog:ENOG410PIPP; InterPro:IPR012334,IPR002022,IPR011050; PFAM:PF00544; SECRETED:SignalP(1-20) AKAW2_41099S BUSCO:EOG09263X1F; COG:C; EggNog:ENOG410PHEW; InterPro:IPR017900,IPR017896,IPR012675,IPR001041, IPR006058,IPR009051,IPR025192,IPR004489,IPR036010; PFAM:PF13534,PF13237,PF13085,PF13183; go_function: GO:0009055 - electron transfer activity [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0051536 - iron-sulfur cluster binding [Evidence IEA]; go_function: GO:0051537 - 2 iron, 2 sulfur cluster binding [Evidence IEA]; go_process: GO:0006099 - tricarboxylic acid cycle [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_41100A COG:G; EggNog:ENOG410PMFD; InterPro:IPR000771,IPR013785; PFAM:PF01116; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_function: GO:0016832 - aldehyde-lyase activity [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_41101A COG:I; EggNog:ENOG410PKHM; InterPro:IPR029154,IPR002204,IPR036291,IPR006115, IPR008927,IPR013328; PFAM:PF03446,PF14833; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0050661 - NADP binding [Evidence IEA]; go_function: GO:0051287 - NAD binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_41102S COG:S; EggNog:ENOG410PSHA; InterPro:IPR006629,IPR037519; PFAM:PF10601 AKAW2_41103S COG:S; EggNog:ENOG410PTDT; InterPro:IPR012589; PFAM:PF08114; TransMembrane:1 (o27-48i); go_function: GO:0030234 - enzyme regulator activity [Evidence IEA]; go_process: GO:0050790 - regulation of catalytic activity [Evidence IEA] AKAW2_41104S COG:S; EggNog:ENOG410PXQH AKAW2_41106A COG:O; EggNog:ENOG410PZF5; InterPro:IPR024991,IPR001841,IPR039903,IPR013083; PFAM:PF12861; go_component: GO:0005680 - anaphase-promoting complex [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_function: GO:0061630 - ubiquitin protein ligase activity [Evidence IEA]; go_function: GO:0097602 - cullin family protein binding [Evidence IEA]; go_process: GO:0031145 - anaphase-promoting complex-dependent catabolic process [Evidence IEA] AKAW2_41107S COG:S; EggNog:ENOG410PX4D AKAW2_41108S COG:G,M; EggNog:ENOG410PNHV; InterPro:IPR036291,IPR008030; PFAM:PF13460,PF05368,PF01370 AKAW2_41109S TransMembrane:1 (o98-117i) AKAW2_41110A COG:U; EggNog:ENOG410PHCI; InterPro:IPR011701,IPR036259; PFAM:PF07690,PF06813; TransMembrane:10 (i76-98o118-138i145-165o180-204i216-235o255-277i477- 494o514-534i541-564o584-605i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_41111A BUSCO:EOG09260PJ9; COG:I,K,T; EggNog:ENOG410QDKD; InterPro:IPR005522,IPR038286; PFAM:PF03770; go_function: GO:0016301 - kinase activity [Evidence IEA]; go_process: GO:0032958 - inositol phosphate biosynthetic process [Evidence IEA] AKAW2_41113A COG:I; EggNog:ENOG410PVGV; InterPro:IPR000873,IPR020845,IPR042099,IPR025110; PFAM:PF00501,PF13193 AKAW2_41114S COG:S; EggNog:ENOG410PJ6W; InterPro:IPR008427; PFAM:PF05730; TransMembrane:8 (i39-55o136-154i166-188o208-234i246-268o288-308i329- 348o368-386i) AKAW2_41115S COG:S; EggNog:ENOG410PWHQ; InterPro:IPR017946; go_function: GO:0008081 - phosphoric diester hydrolase activity [Evidence IEA]; go_process: GO:0006629 - lipid metabolic process [Evidence IEA] AKAW2_41117S COG:S; EggNog:ENOG410PRSR; InterPro:IPR006461; PFAM:PF04749; TransMembrane:2 (i199-218o238-262i) AKAW2_41118S COG:U; EggNog:ENOG410PFGZ; InterPro:IPR014844; PFAM:PF08733; TransMembrane:7 (o88-108i153-173o199-219i231-250o270-289i301-324o336- 354i) AKAW2_41119S COG:S; EggNog:ENOG410PJMW; InterPro:IPR014436,IPR004183; PFAM:PF02900; go_function: GO:0008198 - ferrous iron binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0016701 - oxidoreductase activity, acting on single donors with incorporation of molecular oxygen [Evidence IEA]; go_process: GO:0006725 - cellular aromatic compound metabolic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_41120S COG:S; EggNog:ENOG410PWAF AKAW2_41121A COG:O; EggNog:ENOG410PH8I; InterPro:IPR021109,IPR034163,IPR001461,IPR001969, IPR033121; MEROPS:MER0003668; PFAM:PF00026; TransMembrane:1 (i37-59o); go_function: GO:0004190 - aspartic-type endopeptidase activity [Evidence IEA]; go_process: GO:0006508 - proteolysis [Evidence IEA] AKAW2_41122A COG:K; EggNog:ENOG410PJRC; InterPro:IPR036864,IPR001138; PFAM:PF00172; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_41123A COG:S; EggNog:ENOG410PH4G; InterPro:IPR018791 AKAW2_41124S COG:S; EggNog:ENOG410PRSN; InterPro:IPR024629; PFAM:PF12829 AKAW2_41125A COG:S; EggNog:ENOG410PMR3; InterPro:IPR040632,IPR027417; PFAM:PF17784; TransMembrane:1 (i265-283o) AKAW2_41126S COG:I; EggNog:ENOG410PWJI; InterPro:IPR036291,IPR026055,IPR013120; PFAM:PF07993; TransMembrane:1 (o427-449i); go_function: GO:0080019 - fatty-acyl-CoA reductase (alcohol-forming) activity [Evidence IEA] AKAW2_41127A BUSCO:EOG09264XTW; COG:T; EggNog:ENOG410PFU4; InterPro:IPR000222,IPR036457,IPR001932,IPR015655; go_function: GO:0004722 - protein serine/threonine phosphatase activity [Evidence IEA]; go_function: GO:0016791 - phosphatase activity [Evidence IEA]; go_function: GO:0043169 - cation binding [Evidence IEA]; go_process: GO:0006470 - protein dephosphorylation [Evidence IEA] AKAW2_41128A COG:O; EggNog:ENOG410PJK9; InterPro:IPR002130,IPR026951,IPR020892,IPR003613, IPR029000,IPR013083; PFAM:PF00160,PF04564; go_function: GO:0003755 - peptidyl-prolyl cis-trans isomerase activity [Evidence IEA]; go_function: GO:0004842 - ubiquitin-protein transferase activity [Evidence IEA]; go_process: GO:0000413 - protein peptidyl-prolyl isomerization [Evidence IEA]; go_process: GO:0006457 - protein folding [Evidence IEA]; go_process: GO:0016567 - protein ubiquitination [Evidence IEA] AKAW2_41129A COG:G; EggNog:ENOG410PH7E; InterPro:IPR036652,IPR025762,IPR019050,IPR004443; PFAM:PF09532,PF03853 AKAW2_41130A COG:Q; EggNog:ENOG410PQMA; InterPro:IPR029063,IPR041698,IPR016584; PFAM:PF13649,PF13489,PF08242,PF08241; go_function: GO:0008168 - methyltransferase activity [Evidence IEA] AKAW2_41131S COG:L; EggNog:ENOG410Q4IT; InterPro:IPR001357,IPR036420; PFAM:PF00533,PF12738 AKAW2_41132A BUSCO:EOG09260RGH; COG:O; EggNog:ENOG410PHSB; InterPro:IPR022812,IPR027417,IPR027094,IPR030381; PFAM:PF00350,PF01926; TransMembrane:1 (o817-838i); go_function: GO:0003924 - GTPase activity [Evidence IEA]; go_function: GO:0005525 - GTP binding [Evidence IEA] AKAW2_41133S BUSCO:EOG09264T0J; COG:U; EggNog:ENOG410PG7K; InterPro:IPR005024; PFAM:PF03357; go_process: GO:0007034 - vacuolar transport [Evidence IEA] AKAW2_41134A COG:T; EggNog:ENOG410PWTA; InterPro:IPR017441,IPR008266,IPR000719,IPR011009; PFAM:PF07714,PF00069; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_41135S COG:S; EggNog:ENOG410Q24K AKAW2_41136S BUSCO:EOG092644TW; COG:G; EggNog:ENOG410PGYI; InterPro:IPR020861,IPR035990,IPR000652,IPR022896, IPR013785; PFAM:PF00121; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0004807 - triose-phosphate isomerase activity [Evidence IEA]; go_process: GO:0006096 - glycolytic process [Evidence IEA] AKAW2_41137A BUSCO:EOG09262TUR; COG:U; EggNog:ENOG410PGAP; InterPro:IPR027539; PFAM:PF12519; go_component: GO:0032865 - ERMES complex [Evidence IEA]; go_process: GO:0007005 - mitochondrion organization [Evidence IEA] AKAW2_41138S BUSCO:EOG09264W46; COG:A; EggNog:ENOG410PFZ8; InterPro:IPR033867,IPR001790,IPR043141,IPR043164, IPR040637; PFAM:PF00466,PF17777; go_process: GO:0000027 - ribosomal large subunit assembly [Evidence IEA]; go_process: GO:0042254 - ribosome biogenesis [Evidence IEA] AKAW2_41139A BUSCO:EOG09264G1F; COG:A; EggNog:ENOG410PNAX; InterPro:IPR034143,IPR000504,IPR022023,IPR012677, IPR035979; PFAM:PF12220,PF00076; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0030619 - U1 snRNA binding [Evidence IEA] AKAW2_41140S BUSCO:EOG092656JA; COG:J; EggNog:ENOG410PP1D; InterPro:IPR039927,IPR036249,IPR007741; PFAM:PF05047; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_process: GO:0032543 - mitochondrial translation [Evidence IEA] AKAW2_41141A COG:O; EggNog:ENOG410PSRD; InterPro:IPR038886,IPR017907 AKAW2_41142A BUSCO:EOG092642I5; COG:A; EggNog:ENOG410PK49; InterPro:IPR038959,IPR024977,IPR003613,IPR036322, IPR015943,IPR013915,IPR001680,IPR017986,IPR013083; PFAM:PF12894,PF08606,PF00400; go_component: GO:0000974 - Prp19 complex [Evidence IEA]; go_function: GO:0004842 - ubiquitin-protein transferase activity [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_function: GO:0061630 - ubiquitin protein ligase activity [Evidence IEA]; go_process: GO:0000398 - mRNA splicing, via spliceosome [Evidence IEA]; go_process: GO:0006281 - DNA repair [Evidence IEA]; go_process: GO:0016567 - protein ubiquitination [Evidence IEA] AKAW2_41143S COG:S; EggNog:ENOG410PYIU; InterPro:IPR027911; PFAM:PF15377 AKAW2_41144S BUSCO:EOG09260BSW; COG:J; EggNog:ENOG410PIA1; InterPro:IPR000640,IPR035647,IPR005225,IPR027417, IPR000795,IPR020568,IPR014721,IPR009000; PFAM:PF00009,PF00679; TransMembrane:1 (i362-382o); go_function: GO:0003924 - GTPase activity [Evidence IEA]; go_function: GO:0005525 - GTP binding [Evidence IEA] AKAW2_41145A BUSCO:EOG092653O3; COG:J; EggNog:ENOG410PM0J; InterPro:IPR019495,IPR025721,IPR039771,IPR012340; PFAM:PF10447,PF14382; go_component: GO:0000178 - exosome (RNase complex) [Evidence IEA]; go_function: GO:0003723 - RNA binding [Evidence IEA]; go_process: GO:0006396 - RNA processing [Evidence IEA] AKAW2_41146A BUSCO:EOG09261JUE; COG:U; EggNog:ENOG410PG4R; InterPro:IPR016024,IPR011989,IPR000225; PFAM:PF04826,PF13513,PF00514; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_41148S COG:O; EggNog:ENOG410PJJ8; InterPro:IPR001841,IPR008984,IPR000253,IPR013083; PFAM:PF17123,PF00498; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_41149A COG:S; EggNog:ENOG410PXJZ AKAW2_41150A COG:M; EggNog:ENOG410Q4IV; InterPro:IPR035994,IPR002110,IPR027417,IPR007111, IPR036770,IPR020683; PFAM:PF05729,PF12796,PF00023,PF13637,PF13857; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0009116 - nucleoside metabolic process [Evidence IEA] AKAW2_41151S COG:S; EggNog:ENOG410PKRP; InterPro:IPR021134; PFAM:PF01062; TransMembrane:2 (i51-79o85-105i) AKAW2_41152S SECRETED:SignalP(1-20) AKAW2_41153A COG:S; EggNog:ENOG410PK23; InterPro:IPR041628; PFAM:PF17863 AKAW2_41154S BUSCO:EOG09260FL2; COG:U; EggNog:ENOG410PGPQ; InterPro:IPR016534,IPR038132,IPR006926,IPR006925; PFAM:PF04840,PF04841; go_component: GO:0005737 - cytoplasm [Evidence IEA]; go_process: GO:0006886 - intracellular protein transport [Evidence IEA]; go_process: GO:0007033 - vacuole organization [Evidence IEA] AKAW2_41155A COG:S; EggNog:ENOG410PS4Q; InterPro:IPR022784; PFAM:PF09135 AKAW2_41156S COG:O; EggNog:ENOG410PJUB; InterPro:IPR038765,IPR001394,IPR018200,IPR028889; MEROPS:MER0000864; PFAM:PF13423,PF00443; TransMembrane:1 (i36-55o); go_function: GO:0004843 - thiol-dependent ubiquitin-specific protease activity [Evidence IEA]; go_process: GO:0006511 - ubiquitin-dependent protein catabolic process [Evidence IEA]; go_process: GO:0016579 - protein deubiquitination [Evidence IEA] AKAW2_41157A COG:D,Z; EggNog:ENOG410PPIS; InterPro:IPR011992 AKAW2_41158S COG:O; EggNog:ENOG410PHTV; InterPro:IPR011989,IPR017937,IPR008580,IPR013535, IPR036249,IPR042266,IPR013766; MEROPS:MER0323972; PFAM:PF00085,PF08324,PF05903 AKAW2_41159A TransMembrane:1 (o32-56i) AKAW2_41160A COG:S; EggNog:ENOG410PU5X AKAW2_41161S COG:Q; EggNog:ENOG410PPCM; InterPro:IPR036291,IPR002347; PFAM:PF08659,PF00106,PF13561; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_41163S COG:S; EggNog:ENOG410Q1GA AKAW2_41164S COG:T; EggNog:ENOG410PFPV; InterPro:IPR004813,IPR004648; PFAM:PF03169; TransMembrane:12 (o80-100i112-134o193-217i255-280o327-349i400-423o453- 474i481-503o531-549i570-588o631-653i709-735o); go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_41165A COG:A; EggNog:ENOG410PQRQ; InterPro:IPR000504,IPR025715,IPR035979,IPR012677; PFAM:PF13865,PF00076; go_function: GO:0003676 - nucleic acid binding [Evidence IEA] AKAW2_41166A BUSCO:EOG0926510L; COG:U; EggNog:ENOG410PNEV; InterPro:IPR005024; PFAM:PF03357; go_process: GO:0007034 - vacuolar transport [Evidence IEA] AKAW2_41167S BUSCO:EOG09265BE5; COG:O; EggNog:ENOG410PQIN; InterPro:IPR008978,IPR007052; PFAM:PF04969 AKAW2_41168S BUSCO:EOG09264DJ8; COG:S; EggNog:ENOG410PFET; InterPro:IPR036855,IPR000571,IPR032378; PFAM:PF16543,PF00642; go_function: GO:0046872 - metal ion binding [Evidence IEA] AKAW2_41169S CAZy:GH105; COG:S; EggNog:ENOG410PK1H; InterPro:IPR008928,IPR012341,IPR010905; PFAM:PF07470; SECRETED:SignalP(1-27); go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_41170A COG:O; EggNog:ENOG410PJP9; InterPro:IPR010520,IPR029058; PFAM:PF06500,PF00326 AKAW2_41171S CAZy:AA1; COG:Q; EggNog:ENOG410Q1FT; InterPro:IPR008972,IPR011707,IPR011706,IPR033138, IPR044130,IPR001117; PFAM:PF00394,PF07731,PF07732; go_function: GO:0005507 - copper ion binding [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0006811 - ion transport [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_41172A COG:E; EggNog:ENOG410PMZS; InterPro:IPR023209,IPR006076,IPR006181; PFAM:PF01266; TransMembrane:1 (o6-23i); go_function: GO:0003884 - D-amino-acid oxidase activity [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0071949 - FAD binding [Evidence IEA]; go_process: GO:0046416 - D-amino acid metabolic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_41173A BUSCO:EOG09264SET; COG:S; EggNog:ENOG410PKAF; InterPro:IPR029060,IPR002716,IPR006984; PFAM:PF04900,PF18477; go_component: GO:0032040 - small-subunit processome [Evidence IEA] AKAW2_41174S COG:S; EggNog:ENOG410PIH2; InterPro:IPR015943,IPR036322,IPR034605; go_function: GO:0003712 - transcription coregulator activity [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_function: GO:0008134 - transcription factor binding [Evidence IEA] AKAW2_41175A COG:S; EggNog:ENOG410Q0PI AKAW2_41176A COG:Q; EggNog:ENOG410QE9S; InterPro:IPR036291,IPR002347; PFAM:PF08659,PF00106,PF13561; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_41177S COG:S; EggNog:ENOG410PW0A; InterPro:IPR001810,IPR036047; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_41178S COG:S; EggNog:ENOG410PR07; TransMembrane:1 (o165-185i) AKAW2_41179S COG:S; EggNog:ENOG410PK1P; InterPro:IPR007529; PFAM:PF04438 AKAW2_41180A COG:S; EggNog:ENOG410PU8K AKAW2_41181A COG:S; EggNog:ENOG410PWPT; InterPro:IPR021858; PFAM:PF11951 AKAW2_41182A COG:S; EggNog:ENOG410QAHS; InterPro:IPR036864,IPR001138; PFAM:PF00172; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_41183A COG:S; EggNog:ENOG410PVCV; InterPro:IPR012674,IPR024724,IPR035348; PFAM:PF10703,PF17409 AKAW2_41184S TransMembrane:1 (o6-23i) AKAW2_41185S CAZy:GH16; COG:S; EggNog:ENOG410PJ8X; InterPro:IPR000757,IPR013320; SECRETED:SignalP(1-20); go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_41186A COG:O; EggNog:ENOG410PPR8; InterPro:IPR003653,IPR038765; MEROPS:MER0005204; PFAM:PF02902; TransMembrane:1 (i21-39o); go_function: GO:0008234 - cysteine-type peptidase activity [Evidence IEA]; go_process: GO:0006508 - proteolysis [Evidence IEA] AKAW2_41187A COG:I; EggNog:ENOG410PJT6; InterPro:IPR036938,IPR000326; PFAM:PF01569; TransMembrane:9 (i60-81o93-112i133-155o167-185i192-213o219-239i251- 272o292-313i500-522o) AKAW2_41188S COG:S; EggNog:ENOG410PFVZ; InterPro:IPR005225,IPR001806,IPR027417,IPR003578; PFAM:PF08477,PF00071; go_function: GO:0003924 - GTPase activity [Evidence IEA]; go_function: GO:0005525 - GTP binding [Evidence IEA]; go_process: GO:0007264 - small GTPase mediated signal transduction [Evidence IEA] AKAW2_41189A COG:S; EggNog:ENOG410PSSK; InterPro:IPR013958; PFAM:PF08649; go_component: GO:0042729 - DASH complex [Evidence IEA]; go_component: GO:0072686 - mitotic spindle [Evidence IEA]; go_process: GO:0007052 - mitotic spindle organization [Evidence IEA] AKAW2_41190S COG:C; EggNog:ENOG410PYST; InterPro:IPR013154,IPR013149,IPR036291,IPR014182, IPR011032,IPR020843; PFAM:PF00107,PF08240,PF13602; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_41191A COG:S; EggNog:ENOG410Q1MW AKAW2_41192S TransMembrane:1 (i21-39o) AKAW2_41193S COG:S; EggNog:ENOG410PN0A AKAW2_41194S COG:L; EggNog:ENOG410PKBW; InterPro:IPR027450,IPR032852,IPR005123; PFAM:PF13532; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0006281 - DNA repair [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_41195A COG:S; EggNog:ENOG410PPCP; InterPro:IPR011761,IPR011095,IPR013815; PFAM:PF07478; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0008716 - D-alanine-D-alanine ligase activity [Evidence IEA]; go_function: GO:0046872 - metal ion binding [Evidence IEA] AKAW2_41196A COG:I; EggNog:ENOG410PJH0; InterPro:IPR042099,IPR000873,IPR025110; PFAM:PF00501,PF13193 AKAW2_41197S COG:S; EggNog:ENOG410PQUG; InterPro:IPR013087,IPR036864,IPR001138; PFAM:PF00172; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_41199A COG:S; EggNog:ENOG410PNGJ; TransMembrane:4 (i25-48o68-94i106-126o138-167i) AKAW2_41201A SECRETED:SignalP(1-25) AKAW2_41200S COG:C; EggNog:ENOG410PKU4; InterPro:IPR001155,IPR013785; PFAM:PF00724; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0010181 - FMN binding [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_41202A COG:Q; EggNog:ENOG410PNXK; InterPro:IPR036291,IPR002347; PFAM:PF08659,PF00106,PF13561; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_41203A TransMembrane:1 (o6-29i) AKAW2_41204S COG:I; EggNog:ENOG410PFUR; InterPro:IPR001171,IPR018083; PFAM:PF01222; TransMembrane:11 (o44-65i77-94o100-117i137-161o173-194i227-247o253-271i292- 316o328-344i402-420o426-441i); go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0016628 - oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor [Evidence IEA]; go_process: GO:0016126 - sterol biosynthetic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_41205A COG:K; EggNog:ENOG410PNKD; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_41206S CAZy:GH67; COG:G; EggNog:ENOG410PMC6; InterPro:IPR011099,IPR005154,IPR017853,IPR029018, IPR011395,IPR011100,IPR037054; PFAM:PF07477,PF07488,PF03648; SECRETED:SignalP(1-20); go_component: GO:0005576 - extracellular region [Evidence IEA]; go_function: GO:0046559 - alpha-glucuronidase activity [Evidence IEA]; go_process: GO:0045493 - xylan catabolic process [Evidence IEA] AKAW2_41207S CAZy:GH35; COG:G; EggNog:ENOG410PGTY; InterPro:IPR019801,IPR025300,IPR025972,IPR037110, IPR008979,IPR036833,IPR018954,IPR017853,IPR001944, IPR031330; PFAM:PF13363,PF10435,PF01301,PF13364; SECRETED:SignalP(1-18); go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_41208A COG:S; EggNog:ENOG410PU9F AKAW2_41209A COG:S; EggNog:ENOG410Q2A8; InterPro:IPR001077,IPR036388,IPR016461,IPR029063, IPR036390; PFAM:PF00891; go_function: GO:0008168 - methyltransferase activity [Evidence IEA]; go_function: GO:0008171 - O-methyltransferase activity [Evidence IEA] AKAW2_41210S COG:S; EggNog:ENOG410PNDT; TransMembrane:7 (o12-30i42-63o83-111i123-146o176-195i207-227o247-264i) AKAW2_41212S COG:S; EggNog:ENOG410PXTK; TransMembrane:7 (o6-30i42-65o85-110i122-146o166-191i203-222o242-263i) AKAW2_41213S COG:S; EggNog:ENOG410PGIZ; TransMembrane:1 (o20-41i) AKAW2_41214S COG:S; EggNog:ENOG410PVR9; InterPro:IPR010354,IPR036188; PFAM:PF06100; go_function: GO:0050151 - oleate hydratase activity [Evidence IEA]; go_function: GO:0071949 - FAD binding [Evidence IEA]; go_process: GO:0006631 - fatty acid metabolic process [Evidence IEA] AKAW2_41215A COG:S; EggNog:ENOG410PFNI; InterPro:IPR033310,IPR006166,IPR042530; PFAM:PF02732; go_component: GO:0005634 - nucleus [Evidence IEA]; go_component: GO:0048476 - Holliday junction resolvase complex [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0004518 - nuclease activity [Evidence IEA]; go_process: GO:0006281 - DNA repair [Evidence IEA] AKAW2_41216A BUSCO:EOG09263L52; CAZy:GT4; COG:M; EggNog:ENOG410PFGA; InterPro:IPR001296,IPR027054; PFAM:PF00534,PF13692; TransMembrane:1 (o453-472i); go_function: GO:0004378 - GDP-Man:Man1GlcNAc2-PP-Dol alpha-1,3-mannosyltransferase activity [Evidence IEA]; go_process: GO:0006486 - protein glycosylation [Evidence IEA] AKAW2_41217A COG:Z; EggNog:ENOG410PHIY; InterPro:IPR019821,IPR036961,IPR027417,IPR027640, IPR001752; PFAM:PF16796,PF00225; go_function: GO:0003777 - microtubule motor activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0008017 - microtubule binding [Evidence IEA]; go_process: GO:0007018 - microtubule-based movement [Evidence IEA] AKAW2_41219A COG:E; EggNog:ENOG410PI69; InterPro:IPR020855,IPR023696,IPR006035; PFAM:PF00491; go_function: GO:0016813 - hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines [Evidence IEA]; go_function: GO:0046872 - metal ion binding [Evidence IEA] AKAW2_41220A COG:V; EggNog:ENOG410PHMQ; InterPro:IPR002528; PFAM:PF01554; TransMembrane:9 (o88-109i129-149o169-185i197-219o225-251i272-290o352- 370i422-445o451-474i); go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0015297 - antiporter activity [Evidence IEA]; go_function: GO:0042910 - xenobiotic transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_41221S COG:G; EggNog:ENOG410PKTA; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:11 (i55-72o92-110i122-140o152-173i185-206o212-234i296- 315o335-356i377-396o444-463i475-500o); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_41222A COG:S; EggNog:ENOG410PSZN; InterPro:IPR012919; TransMembrane:1 (i394-413o) AKAW2_41223A COG:D; EggNog:ENOG410QE49; InterPro:IPR036322,IPR015943,IPR001680,IPR019775, IPR020472,IPR017986; PFAM:PF00400; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_41224S BUSCO:EOG09264719; COG:E; EggNog:ENOG410PJYF; InterPro:IPR036263,IPR008238,IPR037039; go_function: GO:0004106 - chorismate mutase activity [Evidence IEA]; go_process: GO:0009073 - aromatic amino acid family biosynthetic process [Evidence IEA]; go_process: GO:0046417 - chorismate metabolic process [Evidence IEA] AKAW2_41225A BUSCO:EOG092649VA; COG:U; EggNog:ENOG410PGEX; InterPro:IPR025602; PFAM:PF13862 AKAW2_41226S COG:H; EggNog:ENOG410PK7M; InterPro:IPR008949 AKAW2_41227A COG:S; EggNog:ENOG410PX0B; InterPro:IPR029032 AKAW2_41228S COG:S; EggNog:ENOG410PSTV AKAW2_41229A CAZy:GT71; COG:G; EggNog:ENOG410PQ9J; InterPro:IPR022751,IPR029044; PFAM:PF11051; TransMembrane:1 (i12-29o); go_function: GO:0016757 - transferase activity, transferring glycosyl groups [Evidence IEA]; go_process: GO:0006486 - protein glycosylation [Evidence IEA] AKAW2_41230S COG:S; EggNog:ENOG410PIXC; InterPro:IPR021858,IPR036864; PFAM:PF11951; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_41231S COG:S; EggNog:ENOG410PK5X AKAW2_41233A COG:M; EggNog:ENOG410PKAA; InterPro:IPR022385,IPR006530 AKAW2_41234S COG:S; EggNog:ENOG410PYAH AKAW2_41235S COG:S; EggNog:ENOG410PN8E; InterPro:IPR004843,IPR029052; PFAM:PF00149,PF12850; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_41237S COG:Z; EggNog:ENOG410PJZQ; InterPro:IPR019821,IPR036961,IPR027417,IPR027640, IPR001752; PFAM:PF16796,PF00225; go_function: GO:0003777 - microtubule motor activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0008017 - microtubule binding [Evidence IEA]; go_process: GO:0007018 - microtubule-based movement [Evidence IEA] AKAW2_41238S BUSCO:EOG09262JZW; COG:J; EggNog:ENOG410PFQ0; InterPro:IPR000649,IPR042529,IPR037171; PFAM:PF01008; TransMembrane:1 (o6-30i); go_process: GO:0044237 - cellular metabolic process [Evidence IEA] AKAW2_41239S COG:S; EggNog:ENOG410PR4F; InterPro:IPR008401; PFAM:PF05839; go_component: GO:0005680 - anaphase-promoting complex [Evidence IEA] AKAW2_41240A BUSCO:EOG09261V87; COG:L; EggNog:ENOG410PHS1; InterPro:IPR013627,IPR016722,IPR007185; PFAM:PF04042,PF08418; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_process: GO:0006260 - DNA replication [Evidence IEA] AKAW2_41241S COG:I; EggNog:ENOG410PFPC; InterPro:IPR011074,IPR036865,IPR036273,IPR001251; PFAM:PF00650,PF03765; TransMembrane:1 (o274-294i) AKAW2_41242S BUSCO:EOG0926374A; COG:C; EggNog:ENOG410PGV3; InterPro:IPR000644; PFAM:PF00571 AKAW2_41243S COG:S; EggNog:ENOG410PGTU AKAW2_41244S COG:K; EggNog:ENOG410PRBK; InterPro:IPR004827; PFAM:PF00170,PF07716; go_function: GO:0003700 - DNA-binding transcription factor activity [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_41245A COG:G; EggNog:ENOG410PMTI; InterPro:IPR005829,IPR005828,IPR003663,IPR036259, IPR020846; PFAM:PF00083,PF07690; TransMembrane:12 (i32-56o76-95i107-124o130-154i166-184o196-219i288-310o322- 348i355-375o395-416i437-455o467-487i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_41246A COG:S; EggNog:ENOG410PHDB; InterPro:IPR036864,IPR021858,IPR001138; PFAM:PF00172,PF11951; TransMembrane:1 (o513-532i); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_41247A COG:P; EggNog:ENOG410PFX2; InterPro:IPR009716,IPR036259; PFAM:PF06963; TransMembrane:10 (i61-78o84-103i123-147o215-236i290-312o332-351i363- 382o388-411i432-451o457-477i); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0005381 - iron ion transmembrane transporter activity [Evidence IEA]; go_process: GO:0034755 - iron ion transmembrane transport [Evidence IEA] AKAW2_41248A BUSCO:EOG0926213Q; COG:I; EggNog:ENOG410PFPY; InterPro:IPR029045,IPR032259,IPR018376; PFAM:PF16113,PF00378; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0003860 - 3-hydroxyisobutyryl-CoA hydrolase activity [Evidence IEA] AKAW2_41249A BUSCO:EOG09264NNY; COG:J; EggNog:ENOG410PNBG; InterPro:IPR002136,IPR013005,IPR023574; PFAM:PF00573; go_component: GO:0005840 - ribosome [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_process: GO:0006412 - translation [Evidence IEA] AKAW2_41250S BUSCO:EOG09262U7S; COG:J; EggNog:ENOG410PMCR; InterPro:IPR036610,IPR008914,IPR035810; PFAM:PF01161 AKAW2_41251A COG:O; EggNog:ENOG410PKYK; InterPro:IPR036286,IPR019533,IPR000223; MEROPS:MER0000597; TransMembrane:1 (i20-39o); go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0008236 - serine-type peptidase activity [Evidence IEA]; go_process: GO:0006508 - proteolysis [Evidence IEA] AKAW2_41252A COG:S; EggNog:ENOG410PN1J; InterPro:IPR010686; PFAM:PF06884 AKAW2_41253A COG:T; EggNog:ENOG410PJ9Y; InterPro:IPR036866,IPR035680,IPR032282,IPR017782, IPR001279; PFAM:PF16123,PF00753; go_function: GO:0004416 - hydroxyacylglutathione hydrolase activity [Evidence IEA]; go_process: GO:0019243 - methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione [Evidence IEA] AKAW2_41254A COG:S; EggNog:ENOG410PKNK; InterPro:IPR007174; PFAM:PF04031; go_component: GO:0090730 - Las1 complex [Evidence IEA]; go_function: GO:0004519 - endonuclease activity [Evidence IEA]; go_process: GO:0006364 - rRNA processing [Evidence IEA] AKAW2_41255A COG:S; EggNog:ENOG410Q2XD AKAW2_41256S BUSCO:EOG0926384F; COG:G; EggNog:ENOG410PGK0; InterPro:IPR016064,IPR017437,IPR002504; PFAM:PF01513; go_function: GO:0003951 - NAD+ kinase activity [Evidence IEA]; go_process: GO:0006741 - NADP biosynthetic process [Evidence IEA]; go_process: GO:0019674 - NAD metabolic process [Evidence IEA] AKAW2_41257S BUSCO:EOG09263ZW6; COG:U; EggNog:ENOG410PMWX; InterPro:IPR024096,IPR007194,IPR016696; PFAM:PF04051; go_component: GO:0030008 - TRAPP complex [Evidence IEA]; go_process: GO:0048193 - Golgi vesicle transport [Evidence IEA] AKAW2_41258A COG:Z; EggNog:ENOG410PJ08; InterPro:IPR033194,IPR009730; PFAM:PF06991 AKAW2_41259S COG:S; EggNog:ENOG410PS0V; InterPro:IPR012340,IPR013970; PFAM:PF08661; go_component: GO:0005634 - nucleus [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_process: GO:0006260 - DNA replication [Evidence IEA]; go_process: GO:0006281 - DNA repair [Evidence IEA]; go_process: GO:0006310 - DNA recombination [Evidence IEA] AKAW2_41260A COG:K; EggNog:ENOG410PIZD; InterPro:IPR000679,IPR042403; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_function: GO:0043565 - sequence-specific DNA binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_41261S BUSCO:EOG09265IT6; COG:A; EggNog:ENOG410PNRK; InterPro:IPR027248,IPR010920,IPR001163; PFAM:PF01423; go_component: GO:0030532 - small nuclear ribonucleoprotein complex [Evidence IEA]; go_process: GO:0008380 - RNA splicing [Evidence IEA] AKAW2_41262A COG:G; EggNog:ENOG410PGQZ; InterPro:IPR004006,IPR004007,IPR012734,IPR036117; PFAM:PF02734,PF02733; go_function: GO:0004371 - glycerone kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006071 - glycerol metabolic process [Evidence IEA] AKAW2_41263A COG:D; EggNog:ENOG410PGFA; InterPro:IPR036317,IPR001373,IPR036388,IPR019559, IPR036390,IPR016159,IPR016158,IPR016157; PFAM:PF10557,PF00888; go_component: GO:0031461 - cullin-RING ubiquitin ligase complex [Evidence IEA]; go_function: GO:0031625 - ubiquitin protein ligase binding [Evidence IEA]; go_process: GO:0006511 - ubiquitin-dependent protein catabolic process [Evidence IEA] AKAW2_41264A BUSCO:EOG092604ML; COG:O; EggNog:ENOG410PG1D; InterPro:IPR021827; PFAM:PF11894; go_component: GO:0005643 - nuclear pore [Evidence IEA] AKAW2_41265S BUSCO:EOG0926009O; COG:L; EggNog:ENOG410PFW9; InterPro:IPR016024,IPR003152,IPR003151,IPR036940, IPR018936,IPR015519,IPR044107,IPR021668,IPR011009, IPR014009,IPR000403; PFAM:PF11640,PF02260,PF00454,PF02259; go_function: GO:0004674 - protein serine/threonine kinase activity [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_function: GO:0016301 - kinase activity [Evidence IEA]; go_process: GO:0000077 - DNA damage checkpoint [Evidence IEA]; go_process: GO:0000723 - telomere maintenance [Evidence IEA]; go_process: GO:0006281 - DNA repair [Evidence IEA]; go_process: GO:0006974 - cellular response to DNA damage stimulus [Evidence IEA]; go_process: GO:0016572 - histone phosphorylation [Evidence IEA] AKAW2_41266S COG:S; EggNog:ENOG410PFIK; InterPro:IPR002882; PFAM:PF01933 AKAW2_41267A BUSCO:EOG092603KJ; COG:L; EggNog:ENOG410PG2A; InterPro:IPR001098,IPR012337,IPR019760,IPR002297, IPR041336,IPR043502; PFAM:PF00476,PF18136; go_component: GO:0005760 - gamma DNA polymerase complex [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0003887 - DNA-directed DNA polymerase activity [Evidence IEA]; go_process: GO:0006260 - DNA replication [Evidence IEA] AKAW2_41268S COG:O; EggNog:ENOG410PTG4; InterPro:IPR001841,IPR017907,IPR018957,IPR013083; PFAM:PF13923,PF14634,PF13920,PF00097,PF13445, PF13639; go_function: GO:0046872 - metal ion binding [Evidence IEA] AKAW2_41269S COG:P; EggNog:ENOG410PHDY; InterPro:IPR002523; TransMembrane:2 (i549-569o581-599i); go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0046873 - metal ion transmembrane transporter activity [Evidence IEA]; go_process: GO:0030001 - metal ion transport [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_41270A COG:K; EggNog:ENOG410PK5H; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; TransMembrane:1 (o245-264i); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_41271A COG:S; EggNog:ENOG410Q2H5 AKAW2_41272A COG:J; EggNog:ENOG410PHI3; InterPro:IPR035531,IPR027417,IPR000795,IPR039263, IPR009001,IPR009000; PFAM:PF00009; go_function: GO:0003924 - GTPase activity [Evidence IEA]; go_function: GO:0005525 - GTP binding [Evidence IEA] AKAW2_41273A COG:A; EggNog:ENOG410PQU6; InterPro:IPR034105,IPR010920,IPR040002,IPR001163; PFAM:PF01423; go_function: GO:0003723 - RNA binding [Evidence IEA]; go_process: GO:0000398 - mRNA splicing, via spliceosome [Evidence IEA]; go_process: GO:0000956 - nuclear-transcribed mRNA catabolic process [Evidence IEA] AKAW2_41274S COG:S; EggNog:ENOG410PR1I; InterPro:IPR024319; PFAM:PF12921 AKAW2_41275A COG:M; EggNog:ENOG410PF9B; InterPro:IPR039516,IPR024078,IPR003737; PFAM:PF02585; SECRETED:SignalP(1-27); go_function: GO:0000225 - N-acetylglucosaminylphosphatidylinositol deacetylase activity [Evidence IEA]; go_process: GO:0006506 - GPI anchor biosynthetic process [Evidence IEA] AKAW2_41276S COG:S; EggNog:ENOG410PKUA; InterPro:IPR014752,IPR014756,IPR024391; PFAM:PF13002 AKAW2_41277A COG:S; EggNog:ENOG410PUQD; TransMembrane:6 (i81-99o119-140i152-172o184-207i227-244o264-282i) AKAW2_41278S COG:I; EggNog:ENOG410Q1IU; InterPro:IPR042099,IPR000873,IPR025110; PFAM:PF00501,PF13193 AKAW2_41280A COG:S; EggNog:ENOG410PP7G; TransMembrane:2 (i228-247o267-294i) AKAW2_41281A COG:S; EggNog:ENOG410PFAR; InterPro:IPR039254; PFAM:PF13668 AKAW2_41282S COG:Q; EggNog:ENOG410PW3M; InterPro:IPR036291,IPR002347,IPR020904; PFAM:PF00106,PF13561; SECRETED:SignalP(1-25); go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_41283A COG:Q; EggNog:ENOG410PFG6; InterPro:IPR026992,IPR027443,IPR005123; PFAM:PF03171,PF14226; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_41284A COG:S; EggNog:ENOG410PS0R AKAW2_41285S COG:O; EggNog:ENOG410QE0U; InterPro:IPR035979,IPR001623,IPR036869,IPR012677, IPR018253; PFAM:PF00226; TransMembrane:1 (o261-279i); go_function: GO:0003676 - nucleic acid binding [Evidence IEA] AKAW2_41286A BUSCO:EOG092620V3; COG:E; EggNog:ENOG410PKK6; InterPro:IPR017703,IPR027266; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_41287A COG:A; EggNog:ENOG410PJA5; InterPro:IPR007722,IPR036189,IPR020084,IPR000086, IPR015797,IPR044099; PFAM:PF05026,PF00293; go_function: GO:0003723 - RNA binding [Evidence IEA]; go_function: GO:0016787 - hydrolase activity [Evidence IEA]; go_function: GO:0030145 - manganese ion binding [Evidence IEA]; go_function: GO:0050072 - m7G(5')pppN diphosphatase activity [Evidence IEA]; go_process: GO:0000184 - nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [Evidence IEA]; go_process: GO:0000290 - deadenylation-dependent decapping of nuclear-transcribed mRNA [Evidence IEA] AKAW2_41288S COG:S; EggNog:ENOG410PIRS; InterPro:IPR025187; PFAM:PF13430; TransMembrane:2 (i76-98o129-149i) AKAW2_41289A COG:J; EggNog:ENOG410PNNT; InterPro:IPR019407,IPR014729; go_function: GO:0000049 - tRNA binding [Evidence IEA]; go_process: GO:0002098 - tRNA wobble uridine modification [Evidence IEA]; go_process: GO:0034227 - tRNA thio-modification [Evidence IEA] AKAW2_41290S BUSCO:EOG092625OH; COG:S; EggNog:ENOG410PFCR; InterPro:IPR009637; PFAM:PF06814; SECRETED:SignalP(1-20); TransMembrane:7 (n7-15c20/21o187-207i219-238o250-279i291-310o322-346i367- 391o411-428i); go_component: GO:0016021 - integral component of membrane [Evidence IEA] AKAW2_41291A COG:S; EggNog:ENOG410PQE9; InterPro:IPR010730; PFAM:PF06985 AKAW2_41292S COG:S; EggNog:ENOG410PK4H; InterPro:IPR010733; PFAM:PF07000 AKAW2_41293A COG:A; EggNog:ENOG410PFQ5; InterPro:IPR037867,IPR036322,IPR015943,IPR001680, IPR017986; PFAM:PF00400; go_component: GO:0048188 - Set1C/COMPASS complex [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_41294S BUSCO:EOG09263OCO; COG:C; EggNog:ENOG410PH4Y; InterPro:IPR018108,IPR023395; PFAM:PF00153 AKAW2_41295S COG:F; EggNog:ENOG410PGIN; InterPro:IPR009078,IPR000358,IPR033909,IPR012348, IPR030475; PFAM:PF00268; TransMembrane:1 (o224-245i); go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0009263 - deoxyribonucleotide biosynthetic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_41296A COG:S; EggNog:ENOG410PSP8; InterPro:IPR039432; PFAM:PF05486 AKAW2_41297A COG:S; EggNog:ENOG410PGP8; InterPro:IPR040324,IPR036322,IPR015943,IPR001680, IPR017986; PFAM:PF00400; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_41298A COG:G; EggNog:ENOG410Q1Z7; InterPro:IPR005829,IPR005828,IPR003663,IPR036259, IPR020846; PFAM:PF00083,PF07690; TransMembrane:12 (i21-39o73-92i104-123o129-148i160-182o194-214i287-308o328- 348i355-375o395-419i431-451o463-480i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_41299S COG:S; EggNog:ENOG410PX6K; InterPro:IPR036568,IPR009288,IPR013024; PFAM:PF06094 AKAW2_41300A COG:O; EggNog:ENOG410PN93; InterPro:IPR036249,IPR036282,IPR010987,IPR004045, IPR004046; PFAM:PF13409,PF00043,PF14497,PF13410,PF13417, PF02798; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0006749 - glutathione metabolic process [Evidence IEA] AKAW2_41301S COG:G,M; EggNog:ENOG410PNHV; InterPro:IPR036291,IPR008030; PFAM:PF13460,PF05368 AKAW2_41302A COG:V; EggNog:ENOG410PK8P; InterPro:IPR036291,IPR001509; PFAM:PF13460,PF05368,PF01370; go_function: GO:0003824 - catalytic activity [Evidence IEA] AKAW2_41303S COG:S; EggNog:ENOG410PPGI; InterPro:IPR036864,IPR001138; PFAM:PF00172; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_41304S COG:G; EggNog:ENOG410Q2PC; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i75-95o115-132i144-163o169-191i203-222o234-252i307- 329o349-367i388-407o413-439i446-469o481-503i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_41305S SECRETED:SignalP(1-17) AKAW2_41306S COG:Q; EggNog:ENOG410PFZM; InterPro:IPR036866,IPR029229,IPR036527,IPR044097, IPR038536,IPR001279,IPR029228; PFAM:PF14864,PF14863,PF00753; go_function: GO:0018741 - alkyl sulfatase activity [Evidence IEA]; go_function: GO:0046983 - protein dimerization activity [Evidence IEA]; go_process: GO:0018909 - dodecyl sulfate metabolic process [Evidence IEA] AKAW2_41307S COG:I; EggNog:ENOG410PJJG; InterPro:IPR005804; PFAM:PF00487; TransMembrane:4 (i54-71o77-98i233-253o259-283i); go_process: GO:0006629 - lipid metabolic process [Evidence IEA] AKAW2_41309S InterPro:IPR036249,IPR036282 AKAW2_41310S COG:Q; EggNog:ENOG410PJKV; InterPro:IPR036291,IPR002347; PFAM:PF08659,PF00106,PF13561; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_41311S COG:Q; EggNog:ENOG410PGBD AKAW2_41312A COG:S; EggNog:ENOG410PYQ3; InterPro:IPR036864,IPR021858,IPR001138; PFAM:PF00172; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_41313A COG:I; EggNog:ENOG410PKEN; InterPro:IPR019826,IPR002018,IPR029058; MEROPS:MER0034664; PFAM:PF00135 AKAW2_41314S COG:S; EggNog:ENOG410PX46; InterPro:IPR036864,IPR021858,IPR001138; PFAM:PF00172; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_41315A COG:S; EggNog:ENOG410PWVT; InterPro:IPR007568; PFAM:PF04479; TransMembrane:7 (o26-44i51-69o89-113i125-143o163-188i209-226o246-265i); go_component: GO:0016021 - integral component of membrane [Evidence IEA] AKAW2_41316A COG:S; EggNog:ENOG410PRCT; InterPro:IPR033877,IPR029479,IPR000415; PFAM:PF00881; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0016657 - oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor [Evidence IEA]; go_process: GO:0034599 - cellular response to oxidative stress [Evidence IEA] AKAW2_41317S TransMembrane:2 (o6-27i39-58o) AKAW2_41318A InterPro:IPR043129 AKAW2_41320S COG:E; EggNog:ENOG410PHHD; InterPro:IPR013057; PFAM:PF01490; TransMembrane:11 (i56-78o84-105i133-156o162-183i190-214o234-255i267- 288o308-327i348-369o381-402i414-437o) AKAW2_41321S COG:G; EggNog:ENOG410PII4; InterPro:IPR029044,IPR007577,IPR039367; SECRETED:SignalP(1-24); go_function: GO:0000009 - alpha-1,6-mannosyltransferase activity [Evidence IEA] AKAW2_41322A COG:S; EggNog:ENOG410PPTM; TransMembrane:1 (o43-63i) AKAW2_41323S COG:S; EggNog:ENOG410PZI5 AKAW2_41325A COG:S; EggNog:ENOG410PN8G; InterPro:IPR021858 AKAW2_41326A COG:P; EggNog:ENOG410PV4W; InterPro:IPR018028,IPR011614,IPR002226,IPR020835, IPR024711,IPR037060,IPR010582; PFAM:PF00199,PF06628; go_function: GO:0004096 - catalase activity [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0006979 - response to oxidative stress [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_41327S COG:E; EggNog:ENOG410PKZ3; InterPro:IPR001692,IPR012131,IPR022695,IPR016161; PFAM:PF00815; go_function: GO:0004399 - histidinol dehydrogenase activity [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0016616 - oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Evidence IEA]; go_function: GO:0046872 - metal ion binding [Evidence IEA]; go_function: GO:0051287 - NAD binding [Evidence IEA]; go_process: GO:0000105 - histidine biosynthetic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_41328S COG:S; EggNog:ENOG410PMHI; InterPro:IPR017359,IPR016135,IPR010541; PFAM:PF06544 AKAW2_41329A COG:S; EggNog:ENOG410PYPW; InterPro:IPR001810,IPR036047; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_41330A COG:S; EggNog:ENOG410PT6U; InterPro:IPR002110,IPR020683,IPR036770; PFAM:PF13857,PF12796,PF00023,PF13637,PF13606; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_41331S SECRETED:SignalP(1-20) AKAW2_41332S COG:Q; EggNog:ENOG410PM5X; InterPro:IPR001128,IPR002401,IPR036396; PFAM:PF00067; TransMembrane:1 (o6-23i); go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_41333S COG:S; EggNog:ENOG410Q2QZ; InterPro:IPR000073,IPR029058; TransMembrane:1 (n3-10c15/16o25-50i) AKAW2_41334S COG:S; EggNog:ENOG410Q2QZ AKAW2_41335A SECRETED:SignalP(1-17) AKAW2_41336S COG:S; EggNog:ENOG410Q1M6 AKAW2_41337A COG:Q; EggNog:ENOG410PU7S; InterPro:IPR029058 AKAW2_41338S COG:C,H; EggNog:ENOG410PIWS; InterPro:IPR036188,IPR002938; go_function: GO:0071949 - FAD binding [Evidence IEA] AKAW2_41340A COG:S; EggNog:ENOG410PJ7E; InterPro:IPR000073,IPR029058; PFAM:PF12697 AKAW2_41341A COG:S; EggNog:ENOG410PW1F; InterPro:IPR010856,IPR027443 AKAW2_50001S COG:I; EggNog:ENOG410PH4X; InterPro:IPR020459,IPR042099,IPR000873,IPR020845; PFAM:PF00501 AKAW2_50002A InterPro:IPR000477; antiSMASH:Cluster_5.1 AKAW2_50003A COG:S; EggNog:ENOG410QDNC; antiSMASH:Cluster_5.1 AKAW2_50004A antiSMASH:Cluster_5.1 AKAW2_50005S COG:S; EggNog:ENOG410PVNY; antiSMASH:Cluster_5.1 AKAW2_50006S COG:S; EggNog:ENOG410PJDC; InterPro:IPR000073,IPR029058,IPR013595; MEROPS:MER0000440; PFAM:PF08386,PF00561; TransMembrane:1 (i21-39o); antiSMASH:Cluster_5.1 AKAW2_50007A COG:I; EggNog:ENOG410PMS5; antiSMASH:Cluster_5.1 AKAW2_50008A COG:U; EggNog:ENOG410PH2C; InterPro:IPR022812,IPR027417; antiSMASH:Cluster_5.1 AKAW2_50009S COG:I; EggNog:ENOG410QE59; InterPro:IPR000873,IPR009081,IPR036291,IPR013120, IPR042099,IPR020845; PFAM:PF00550,PF01370,PF07993; SMCOG1010:NAD-dependent epimerase/dehydratase; antiSMASH:Cluster_5.1 AKAW2_50010S COG:S; EggNog:ENOG410PZ4Z; antiSMASH:Cluster_5.1 AKAW2_50011S SECRETED:SignalP(1-20); antiSMASH:Cluster_5.1 AKAW2_50012S COG:S; EggNog:ENOG410Q2IR; antiSMASH:Cluster_5.1 AKAW2_50013A COG:Q; EggNog:ENOG410PFKE; InterPro:IPR036291,IPR013968; antiSMASH:Cluster_5.1 AKAW2_50014A COG:I; EggNog:ENOG410PM3W; antiSMASH:Cluster_5.1 AKAW2_50015A COG:I; EggNog:ENOG410PM3W; InterPro:IPR020807,IPR042104; antiSMASH:Cluster_5.1 AKAW2_50016A antiSMASH:Cluster_5.1 AKAW2_50018A COG:O; EggNog:ENOG410Q86P; InterPro:IPR036852,IPR000209,IPR015500; MEROPS:MER0000320; PFAM:PF00082; TransMembrane:3 (i395-413o419-436i622-645o); go_function: GO:0004252 - serine-type endopeptidase activity [Evidence IEA]; go_function: GO:0008236 - serine-type peptidase activity [Evidence IEA]; go_process: GO:0006508 - proteolysis [Evidence IEA] AKAW2_50019S COG:S; EggNog:ENOG410PXBA AKAW2_50020S COG:S; EggNog:ENOG410PIQ1; InterPro:IPR001279,IPR036866; PFAM:PF00753 AKAW2_50021A COG:S; EggNog:ENOG410PNN8; InterPro:IPR007272; PFAM:PF04143; TransMembrane:6 (n23-33c41/42o57-77i185-204o210-231i273-290o302-324i336- 362o) AKAW2_50022S COG:S; EggNog:ENOG410PWU1; InterPro:IPR010699; PFAM:PF06912; TransMembrane:5 (o86-107i119-142o148-168i207-224o230-249i) AKAW2_50023A COG:G; EggNog:ENOG410PI9I; InterPro:IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i68-90o110-131i143-161o167-187i199-219o231-250i300- 323o335-352i364-387o393-411i423-440o460-477i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_50024S COG:E; EggNog:ENOG410PMQJ; InterPro:IPR002220,IPR013785; PFAM:PF00701; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0016829 - lyase activity [Evidence IEA] AKAW2_50025A COG:I; EggNog:ENOG410PNNB; InterPro:IPR029154,IPR015815,IPR036291,IPR006115, IPR008927,IPR013328; PFAM:PF03446,PF14833; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0050661 - NADP binding [Evidence IEA]; go_function: GO:0051287 - NAD binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_50026A COG:K; EggNog:ENOG410PYGI; InterPro:IPR036236,IPR013087,IPR007219; PFAM:PF00096,PF04082; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA] AKAW2_50027A COG:E; EggNog:ENOG410PVJ9; InterPro:IPR002821,IPR008040,IPR003692; PFAM:PF01968,PF05378,PF02538; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_50028S COG:Q; EggNog:ENOG410PIDT; InterPro:IPR020946,IPR036188,IPR000960; PFAM:PF13450; go_function: GO:0004499 - N,N-dimethylaniline monooxygenase activity [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_function: GO:0050661 - NADP binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_50029A COG:I; EggNog:ENOG410PKHM; InterPro:IPR029154,IPR036291,IPR006115,IPR008927, IPR013328; PFAM:PF03446,PF14833; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0050661 - NADP binding [Evidence IEA]; go_function: GO:0051287 - NAD binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_50030A COG:S; EggNog:ENOG410PHBH; TransMembrane:2 (i552-570o582-610i) AKAW2_50031S COG:S; EggNog:ENOG410PPY1; InterPro:IPR002523; PFAM:PF01544; TransMembrane:2 (o351-376i388-410o); go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0046873 - metal ion transmembrane transporter activity [Evidence IEA]; go_process: GO:0030001 - metal ion transport [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_50032A TransMembrane:7 (o12-34i46-71o91-108i129-147o159-182i194-217o237-257i) AKAW2_50033A COG:S; EggNog:ENOG410PKCI AKAW2_50034S COG:G; EggNog:ENOG410PIBT; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:14 (i33-58o70-88i100-120o126-147i159-176o188-207i228-253o259- 281i302-325o337-355i367-388o394-417i429-453o503-524i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_50035A COG:S; EggNog:ENOG410PV15; InterPro:IPR001810,IPR036047,IPR032675; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_50036A COG:C; EggNog:ENOG410PWXW; InterPro:IPR036188 AKAW2_50037A COG:S; EggNog:ENOG410PWV9; InterPro:IPR036047; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_50038S COG:O; EggNog:ENOG410PU84; InterPro:IPR011118,IPR029058; PFAM:PF07519; SECRETED:SignalP(1-17) AKAW2_50039S COG:S; EggNog:ENOG410PNG8; InterPro:IPR038595,IPR025659,IPR007612; PFAM:PF04525 AKAW2_50040S COG:S; EggNog:ENOG410PN83; TransMembrane:6 (i30-51o57-78i105-125o137-157i221-241o247-270i) AKAW2_50041A COG:S; EggNog:ENOG410PNA6; InterPro:IPR036864,IPR001138; PFAM:PF00172; TransMembrane:2 (o239-257i361-381o); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_50042A COG:S; EggNog:ENOG410PI7F; InterPro:IPR001433,IPR017938,IPR012349,IPR039261; PFAM:PF00175; TransMembrane:1 (o508-527i); go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_50044S COG:M; EggNog:ENOG410PRDD; InterPro:IPR002110,IPR036770,IPR020683; PFAM:PF13857,PF12796,PF00023,PF13637,PF13606; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_50045S COG:S; EggNog:ENOG410PW15 AKAW2_50046A COG:G; EggNog:ENOG410PKV4; InterPro:IPR020846,IPR005828,IPR036259; TransMembrane:3 (i12-33o73-93i100-119o); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_50047A COG:I; EggNog:ENOG410PVDS; InterPro:IPR006176,IPR006108,IPR036291,IPR008927, IPR013328; PFAM:PF02737,PF00725; go_function: GO:0003857 - 3-hydroxyacyl-CoA dehydrogenase activity [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0006631 - fatty acid metabolic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_50048S COG:I; EggNog:ENOG410PV78; InterPro:IPR023606,IPR003673; PFAM:PF02515; go_function: GO:0008410 - CoA-transferase activity [Evidence IEA] AKAW2_50049A COG:S; EggNog:ENOG410PNBP; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_50050S COG:T; EggNog:ENOG410QDMZ; InterPro:IPR011042,IPR000033; PFAM:PF00058 AKAW2_50051A COG:G; EggNog:ENOG410QDJA; InterPro:IPR011701,IPR036259; PFAM:PF07690; TransMembrane:10 (i12-32o38-61i68-89o101-122i170-194o206-224i236-255o261- 284i296-316o328-351i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_50052S COG:S; EggNog:ENOG410PKHJ; InterPro:IPR007325,IPR037175; PFAM:PF04199; go_function: GO:0004061 - arylformamidase activity [Evidence IEA]; go_process: GO:0019441 - tryptophan catabolic process to kynurenine [Evidence IEA] AKAW2_50053A COG:S; EggNog:ENOG410Q2ZQ; InterPro:IPR009413; PFAM:PF06355; go_process: GO:0019836 - hemolysis by symbiont of host erythrocytes [Evidence IEA] AKAW2_50055A COG:S; EggNog:ENOG410PNG9; InterPro:IPR008922,IPR002227; PFAM:PF00264; SECRETED:SignalP(1-17); go_function: GO:0016491 - oxidoreductase activity [Evidence IEA] AKAW2_50056A COG:S; EggNog:ENOG410PQK1; InterPro:IPR036864,IPR001138; PFAM:PF00172; TransMembrane:1 (i202-219o); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_50059S CAZy:PL1; COG:G; EggNog:ENOG410PIPP; InterPro:IPR012334,IPR002022,IPR011050; PFAM:PF00544; SECRETED:SignalP(1-19) AKAW2_50060S COG:F; EggNog:ENOG410Q1I2; InterPro:IPR000845,IPR035994; PFAM:PF01048; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_process: GO:0009116 - nucleoside metabolic process [Evidence IEA] AKAW2_50061S COG:L; EggNog:ENOG410Q6I3 AKAW2_50062A COG:Q; EggNog:ENOG410PJSN; InterPro:IPR036291,IPR002347,IPR020904; PFAM:PF00106,PF13561; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_50063A COG:Z; EggNog:ENOG410PJDD; InterPro:IPR011990,IPR019734,IPR013026; PFAM:PF13374,PF13176,PF13424,PF07721; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_50064S TransMembrane:1 (i200-218o) AKAW2_50065S COG:P; EggNog:ENOG410PNP3; InterPro:IPR004798,IPR004837; PFAM:PF01699; TransMembrane:10 (o77-96i108-131o137-161i173-195o207-228i256-276o288- 311i323-349o355-376i383-402o); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0015369 - calcium:proton antiporter activity [Evidence IEA]; go_process: GO:0006816 - calcium ion transport [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_50066A COG:P; EggNog:ENOG410Q2D1; InterPro:IPR004837; PFAM:PF01699; TransMembrane:11 (i61-80o86-106i118-137o143-166i187-204o224-242i292- 312o324-346i358-378o390-407i414-433o); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_50067S COG:P; EggNog:ENOG410Q2X9; InterPro:IPR006068,IPR018303,IPR023298,IPR023299, IPR001757,IPR006408,IPR004014,IPR036412,IPR008250, IPR023214; PFAM:PF00689,PF13246,PF00122,PF00690,PF00702; TransMembrane:8 (i138-155o175-193i342-364o384-410i910-929o974-995i1007- 1029o1035-1051i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0000166 - nucleotide binding [Evidence IEA]; go_function: GO:0005388 - calcium transmembrane transporter activity, phosphorylative mechanism [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0070588 - calcium ion transmembrane transport [Evidence IEA] AKAW2_50068A COG:S; EggNog:ENOG410Q07K; TransMembrane:1 (o405-422i) AKAW2_50069A COG:S; EggNog:ENOG410Q5AU AKAW2_50070S COG:S; EggNog:ENOG410PXPI AKAW2_50071S CAZy:AA7; COG:C; EggNog:ENOG410PM8F; InterPro:IPR006093,IPR006094,IPR036318,IPR016169, IPR016166,IPR016167; PFAM:PF01565; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_function: GO:0071949 - FAD binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_50072S COG:Q; EggNog:ENOG410PUUN; InterPro:IPR013154,IPR013149,IPR036291,IPR011032, IPR020843; PFAM:PF00107,PF08240,PF13602; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_50074S COG:S; EggNog:ENOG410PN7M AKAW2_50075S InterPro:IPR002110,IPR020683,IPR036770; PFAM:PF13606,PF12796; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_50076A COG:S; EggNog:ENOG410Q1UX; TransMembrane:1 (o333-350i) AKAW2_50077A SECRETED:SignalP(1-19); TransMembrane:1 (n3-14c19/20o462-483i) AKAW2_50078A TransMembrane:1 (i152-170o) AKAW2_50080A COG:S; EggNog:ENOG410PQIG AKAW2_50082A TransMembrane:1 (o60-78i) AKAW2_50084A COG:S; EggNog:ENOG410Q266 AKAW2_50085A SECRETED:SignalP(1-27) AKAW2_50086S InterPro:IPR011009 AKAW2_50088A COG:S; EggNog:ENOG410Q1HV; InterPro:IPR022198 AKAW2_50089A COG:S; EggNog:ENOG410Q1HV AKAW2_50091A COG:O; EggNog:ENOG410PN65; InterPro:IPR001841,IPR016035,IPR002641,IPR017907; PFAM:PF01734; go_process: GO:0006629 - lipid metabolic process [Evidence IEA] AKAW2_50092S TransMembrane:7 (i12-38o50-75i87-108o114-133i145-165o177-196i208-228o) AKAW2_50093A COG:S; EggNog:ENOG410PYN0 AKAW2_50094A COG:S; EggNog:ENOG410PMIB; InterPro:IPR016137,IPR036305; PFAM:PF00615; TransMembrane:4 (i69-90o122-141i153-177o189-209i) AKAW2_50095S COG:S; EggNog:ENOG410PGXJ; TransMembrane:7 (o24-42i54-72o78-100i112-136o156-175i187-210o222-240i) AKAW2_50097A COG:S; EggNog:ENOG410Q1BA; InterPro:IPR039261; TransMembrane:7 (o20-38i77-98o110-130i142-161o173-193i200-219o231-252i) AKAW2_50098A COG:S; EggNog:ENOG410PJF1 AKAW2_50100S COG:S; EggNog:ENOG410PQ0F; InterPro:IPR027377; PFAM:PF13695 AKAW2_50105S COG:O; EggNog:ENOG410PHEM; InterPro:IPR014851,IPR000086,IPR003959,IPR027417, IPR003593,IPR015797,IPR003960; PFAM:PF00293,PF08740,PF00004; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016787 - hydrolase activity [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA] AKAW2_50107A InterPro:IPR003347 AKAW2_50113S COG:B; EggNog:ENOG410PQ5M; InterPro:IPR009071,IPR036910; PFAM:PF00505 AKAW2_50115S COG:S; EggNog:ENOG410Q1BA; TransMembrane:1 (o38-58i) AKAW2_50118S COG:S; EggNog:ENOG410Q1BA; InterPro:IPR039261; TransMembrane:7 (o20-38i77-98o110-130i142-161o173-193i200-219o231-252i) AKAW2_50120A COG:S; EggNog:ENOG410PGXJ; TransMembrane:3 (o57-75i87-110o122-142i) AKAW2_50122S InterPro:IPR013087 AKAW2_50123S COG:S; EggNog:ENOG410PQ5R AKAW2_50125A TransMembrane:1 (o44-65i) AKAW2_50127A COG:S; EggNog:ENOG410Q266 AKAW2_50128A InterPro:IPR001841,IPR013083; PFAM:PF17123,PF13923,PF00097,PF13639,PF12861, PF12678; antiSMASH:Cluster_5.2 AKAW2_50129S COG:S; EggNog:ENOG410PPS6; TransMembrane:4 (i40-60o95-116i128-149o155-180i); antiSMASH:Cluster_5.2 AKAW2_50130S antiSMASH:Cluster_5.2 AKAW2_50131A COG:M; EggNog:ENOG410Q1TJ; InterPro:IPR002110,IPR036770,IPR020683; PFAM:PF13857,PF12796,PF00023,PF13637,PF13606; antiSMASH:Cluster_5.2; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_50133A COG:D; EggNog:ENOG410PVG0; InterPro:IPR036397; go_function: GO:0003676 - nucleic acid binding [Evidence IEA] AKAW2_50134A COG:S; EggNog:ENOG410QDUF; InterPro:IPR007751,IPR029058 AKAW2_50135S COG:S; EggNog:ENOG410PKSA; InterPro:IPR011009 AKAW2_50138A COG:S; EggNog:ENOG410PHAM; InterPro:IPR029057,IPR000836,IPR027417,IPR036412, IPR023214; PFAM:PF12710,PF14681,PF13207; go_process: GO:0009116 - nucleoside metabolic process [Evidence IEA] AKAW2_50141A COG:S; EggNog:ENOG410PPA6; InterPro:IPR012177,IPR039582,IPR033469; go_function: GO:0050333 - thiamin-triphosphatase activity [Evidence IEA]; go_process: GO:0006772 - thiamine metabolic process [Evidence IEA] AKAW2_50143S COG:S; EggNog:ENOG410PSQG; InterPro:IPR036389; TransMembrane:2 (o49-68i324-344o); go_function: GO:0004525 - ribonuclease III activity [Evidence IEA]; go_process: GO:0006396 - RNA processing [Evidence IEA] AKAW2_50144S COG:F; EggNog:ENOG410PH1X; InterPro:IPR005919,IPR029057,IPR006094,IPR000836, IPR036318,IPR016166; PFAM:PF04275,PF01565,PF00156; go_component: GO:0005737 - cytoplasm [Evidence IEA]; go_function: GO:0004631 - phosphomevalonate kinase activity [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_function: GO:0071949 - FAD binding [Evidence IEA]; go_process: GO:0006695 - cholesterol biosynthetic process [Evidence IEA]; go_process: GO:0009116 - nucleoside metabolic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_50145S COG:H; EggNog:ENOG410PFKM; InterPro:IPR018234,IPR043134,IPR001474,IPR020602, IPR043133; PFAM:PF01227; go_function: GO:0003934 - GTP cyclohydrolase I activity [Evidence IEA]; go_process: GO:0046654 - tetrahydrofolate biosynthetic process [Evidence IEA] AKAW2_50146S COG:S; EggNog:ENOG410PJZ6; InterPro:IPR027417 AKAW2_50148A COG:S; EggNog:ENOG410PVR9; InterPro:IPR010354,IPR036188; go_function: GO:0050151 - oleate hydratase activity [Evidence IEA]; go_function: GO:0071949 - FAD binding [Evidence IEA]; go_process: GO:0006631 - fatty acid metabolic process [Evidence IEA] AKAW2_50149A COG:S; EggNog:ENOG410PKSA AKAW2_50150A COG:U; EggNog:ENOG410PH2C; InterPro:IPR022812,IPR027417,IPR001401,IPR000375, IPR030381,IPR020850; PFAM:PF00350,PF01031; go_function: GO:0003924 - GTPase activity [Evidence IEA]; go_function: GO:0005525 - GTP binding [Evidence IEA] AKAW2_50151S COG:S; EggNog:ENOG410PNUZ; InterPro:IPR031348 AKAW2_50152A InterPro:IPR036864,IPR001138; PFAM:PF00172; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_50153S COG:B; EggNog:ENOG410PQ5M; InterPro:IPR036910 AKAW2_50156S COG:S; EggNog:ENOG410PYHX AKAW2_50159S COG:S; EggNog:ENOG410Q1BA; TransMembrane:2 (o27-47i54-75o) AKAW2_50160S InterPro:IPR039261 AKAW2_50162A COG:S; EggNog:ENOG410PGXJ; TransMembrane:7 (o20-38i45-66o72-95i107-131o151-170i182-205o217-237i) AKAW2_50163A COG:S; EggNog:ENOG410QEHG AKAW2_50165A COG:S; EggNog:ENOG410PQZF AKAW2_50166A COG:S; EggNog:ENOG410PU0E AKAW2_50167S COG:S; EggNog:ENOG410Q2MM AKAW2_50171S InterPro:IPR039261 AKAW2_50177S COG:S; EggNog:ENOG410PQIG AKAW2_50179S TransMembrane:1 (i152-170o) AKAW2_50180A TransMembrane:1 (i21-39o) AKAW2_50187A COG:Q; EggNog:ENOG410PPEB; InterPro:IPR036291,IPR002347; PFAM:PF08659,PF00106,PF13561; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_50192S COG:S; EggNog:ENOG410PYHX AKAW2_50193A COG:S; EggNog:ENOG410PQIG AKAW2_50196S COG:T; EggNog:ENOG410PV4K; InterPro:IPR000719,IPR011009,IPR017441; PFAM:PF00069; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_50197S COG:D; EggNog:ENOG410PVG0; InterPro:IPR000477; PFAM:PF00078 AKAW2_50199S COG:S; EggNog:ENOG410PT48 AKAW2_50200A COG:S; EggNog:ENOG410PJZ6; InterPro:IPR027417 AKAW2_50201A COG:S; EggNog:ENOG410PJZ6 AKAW2_50202A COG:H; EggNog:ENOG410PFKM; InterPro:IPR018234,IPR043134,IPR001474,IPR020602, IPR043133; PFAM:PF01227; go_function: GO:0003934 - GTP cyclohydrolase I activity [Evidence IEA]; go_process: GO:0046654 - tetrahydrofolate biosynthetic process [Evidence IEA] AKAW2_50203A COG:F; EggNog:ENOG410PH1X; InterPro:IPR005919,IPR029057,IPR006094,IPR000836, IPR036318,IPR016166; PFAM:PF04275,PF01565,PF00156; go_component: GO:0005737 - cytoplasm [Evidence IEA]; go_function: GO:0004631 - phosphomevalonate kinase activity [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_function: GO:0071949 - FAD binding [Evidence IEA]; go_process: GO:0006695 - cholesterol biosynthetic process [Evidence IEA]; go_process: GO:0009116 - nucleoside metabolic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_50204A COG:S; EggNog:ENOG410PSQG; InterPro:IPR000999,IPR036389; TransMembrane:2 (o46-67i355-375o); go_function: GO:0004525 - ribonuclease III activity [Evidence IEA]; go_process: GO:0006396 - RNA processing [Evidence IEA] AKAW2_50205A COG:S; EggNog:ENOG410Q256; InterPro:IPR036389; go_function: GO:0004525 - ribonuclease III activity [Evidence IEA]; go_process: GO:0006396 - RNA processing [Evidence IEA] AKAW2_50206S COG:S; EggNog:ENOG410PPA6; InterPro:IPR012177,IPR039582,IPR033469; go_function: GO:0050333 - thiamin-triphosphatase activity [Evidence IEA]; go_process: GO:0006772 - thiamine metabolic process [Evidence IEA] AKAW2_50209S COG:S; EggNog:ENOG410PHAM; InterPro:IPR029057,IPR027417,IPR036412,IPR023214; PFAM:PF12710,PF13207 AKAW2_50210S InterPro:IPR011009 AKAW2_50211A COG:S; EggNog:ENOG410Q1HV; InterPro:IPR022198 AKAW2_50213A COG:K; EggNog:ENOG410PKPA; InterPro:IPR036236,IPR013087; PFAM:PF00096; TransMembrane:2 (i83-100o120-140i) AKAW2_50214S COG:S; EggNog:ENOG410PQ5R AKAW2_50215A InterPro:IPR036236,IPR013087 AKAW2_50217A InterPro:IPR021264; TransMembrane:1 (o18-37i) AKAW2_50218A TransMembrane:1 (o56-76i) AKAW2_50221S COG:S; EggNog:ENOG410PXKF; TransMembrane:1 (o110-126i) AKAW2_50222A COG:S; EggNog:ENOG410Q07T AKAW2_50223S COG:S; EggNog:ENOG410PV1W AKAW2_50225S COG:S; EggNog:ENOG410PKSA AKAW2_50226S COG:S; EggNog:ENOG410PKSA; InterPro:IPR011009; SECRETED:SignalP(1-20) AKAW2_50232S TransMembrane:1 (o89-106i) AKAW2_50233A COG:S; EggNog:ENOG410PQ6D AKAW2_50237A InterPro:IPR001138,IPR036864; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_50242A COG:S; EggNog:ENOG410Q2ZJ AKAW2_50245S COG:S; EggNog:ENOG410QDNA; InterPro:IPR000477,IPR036397,IPR012337,IPR005135, IPR002156,IPR036691,IPR043502; PFAM:PF00078,PF14529,PF00075; TransMembrane:1 (o1013-1035i); go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0004523 - RNA-DNA hybrid ribonuclease activity [Evidence IEA] AKAW2_50246S SECRETED:SignalP(1-27) AKAW2_50248A COG:S; EggNog:ENOG410PMIB AKAW2_50249A COG:S; EggNog:ENOG410PMIB; TransMembrane:1 (o33-52i) AKAW2_50250S COG:S; EggNog:ENOG410PZK5 AKAW2_50254A COG:S; EggNog:ENOG410Q551; InterPro:IPR003615; PFAM:PF13391 AKAW2_50256A COG:S; EggNog:ENOG410Q1RM; InterPro:IPR013087; TransMembrane:1 (i268-290o) AKAW2_50257S InterPro:IPR013087 AKAW2_50260A COG:S; EggNog:ENOG410PQ5R AKAW2_50262S COG:L; EggNog:ENOG410Q1Z8; TransMembrane:1 (o195-214i) AKAW2_50263S COG:S; EggNog:ENOG410Q1BA; InterPro:IPR039261; TransMembrane:7 (o20-38i77-98o110-130i142-161o173-194i206-223o229-251i) AKAW2_50265A COG:S; EggNog:ENOG410PGXJ; TransMembrane:7 (o24-43i55-73o79-100i112-136o156-175i187-210o222-242i) AKAW2_50267S COG:S; EggNog:ENOG410PMIB; InterPro:IPR016137,IPR036305; PFAM:PF00615; TransMembrane:3 (o22-44i51-70o153-174i) AKAW2_50270A SECRETED:SignalP(1-19); TransMembrane:5 (n8-19c27/28o37-57i66-84o96-115i127-147o159-179i) AKAW2_50271S COG:O; EggNog:ENOG410PN65; InterPro:IPR001841,IPR016035,IPR002641,IPR017907; PFAM:PF01734; go_process: GO:0006629 - lipid metabolic process [Evidence IEA] AKAW2_50272S COG:S; EggNog:ENOG410Q1HV; InterPro:IPR022198; PFAM:PF12520 AKAW2_50273A COG:S; EggNog:ENOG410Q1HV; InterPro:IPR011009 AKAW2_50274S COG:S; EggNog:ENOG410Q1HV; InterPro:IPR011009 AKAW2_50276S COG:S; EggNog:ENOG410Q2F7; InterPro:IPR027443 AKAW2_50278S COG:S; EggNog:ENOG410PMEK; InterPro:IPR011990; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_50279S COG:U; EggNog:ENOG410PIUK; InterPro:IPR022812,IPR027417; PFAM:PF00350 AKAW2_50280S COG:U; EggNog:ENOG410PIUK; InterPro:IPR022812,IPR020850 AKAW2_50281S COG:U; EggNog:ENOG410PH2C; InterPro:IPR022812,IPR027417 AKAW2_50282S COG:U; EggNog:ENOG410PH2C; InterPro:IPR022812,IPR027417 AKAW2_50283S COG:U; EggNog:ENOG410PH2C; InterPro:IPR022812,IPR020850 AKAW2_50284S InterPro:IPR011009 AKAW2_50285A COG:S; EggNog:ENOG410Q1CS; InterPro:IPR002110,IPR036770,IPR020683; PFAM:PF13857,PF12796,PF00023,PF13637,PF13606; TransMembrane:1 (i56-73o); go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_50286S COG:S; EggNog:ENOG410PPS6; TransMembrane:4 (i74-94o129-150i162-183o189-214i) AKAW2_50287A COG:M; EggNog:ENOG410Q1TJ; InterPro:IPR002110,IPR036770,IPR001995,IPR020683; PFAM:PF13857,PF12796,PF00023,PF13637,PF13606; go_function: GO:0004190 - aspartic-type endopeptidase activity [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0006508 - proteolysis [Evidence IEA] AKAW2_50288A COG:O; EggNog:ENOG410PK6K AKAW2_50289S COG:L; EggNog:ENOG410Q1Z8; TransMembrane:1 (o195-214i) AKAW2_50290S COG:S; EggNog:ENOG410PKVH AKAW2_50291S COG:S; EggNog:ENOG410PV9A; InterPro:IPR003615; PFAM:PF13391 AKAW2_50292A InterPro:IPR009027,IPR011320,IPR037056; PFAM:PF01693 AKAW2_50298S COG:B; EggNog:ENOG410PQ5M; InterPro:IPR009071,IPR036910; PFAM:PF00505 AKAW2_50301S COG:L; EggNog:ENOG410Q1Z8; TransMembrane:1 (o195-214i) AKAW2_50304A COG:S; EggNog:ENOG410Q1RM; InterPro:IPR013087 AKAW2_50309A COG:S; EggNog:ENOG410Q22G; InterPro:IPR017877 AKAW2_50310S COG:S; EggNog:ENOG410PW63; InterPro:IPR021842 AKAW2_50311S COG:S; EggNog:ENOG410PW63; InterPro:IPR021842 AKAW2_50312S COG:O; EggNog:ENOG410PGCA; InterPro:IPR036034,IPR009003,IPR041489,IPR001940, IPR025926; MEROPS:MER0003297; PFAM:PF17820,PF12812,PF13365,PF00089; go_function: GO:0004252 - serine-type endopeptidase activity [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0006508 - proteolysis [Evidence IEA] AKAW2_50314A COG:S; EggNog:ENOG410PYHX AKAW2_50317A COG:S; EggNog:ENOG410Q0VI AKAW2_50318A COG:S; EggNog:ENOG410PZHV AKAW2_50321A InterPro:IPR011009 AKAW2_50322S COG:S; EggNog:ENOG410Q266 AKAW2_50326A COG:S; EggNog:ENOG410PQ5R AKAW2_50329S InterPro:IPR000679,IPR013088; PFAM:PF00320; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_function: GO:0043565 - sequence-specific DNA binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_50330S COG:S; EggNog:ENOG410Q551; InterPro:IPR003615; PFAM:PF13391 AKAW2_50331S COG:S; EggNog:ENOG410PQZF; TransMembrane:1 (i132-152o) AKAW2_50338S COG:S; EggNog:ENOG410PMIB; InterPro:IPR036305; TransMembrane:7 (o22-44i51-69o89-106i152-173o205-224i236-260o272-292i) AKAW2_50339S COG:S; EggNog:ENOG410PYN0 AKAW2_50340S COG:S; EggNog:ENOG410PXZA; InterPro:IPR011333 AKAW2_50341A COG:O; EggNog:ENOG410PN65; InterPro:IPR001841,IPR016035,IPR002641,IPR017907, IPR016181,IPR000182,IPR013083; PFAM:PF01734,PF00583; go_function: GO:0008080 - N-acetyltransferase activity [Evidence IEA]; go_process: GO:0006629 - lipid metabolic process [Evidence IEA] AKAW2_50342A COG:S; EggNog:ENOG410PXZA AKAW2_50343A COG:S; EggNog:ENOG410PY6S; InterPro:IPR000210,IPR011333; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_50344S COG:S; EggNog:ENOG410PPMG; InterPro:IPR027796; PFAM:PF14441 AKAW2_50345S COG:U; EggNog:ENOG410PH2C; InterPro:IPR022812,IPR027417,IPR001401,IPR000375, IPR030381,IPR020850; PFAM:PF00350,PF01031; go_function: GO:0003924 - GTPase activity [Evidence IEA]; go_function: GO:0005525 - GTP binding [Evidence IEA] AKAW2_50347S COG:S; EggNog:ENOG410PKSA AKAW2_50348A SECRETED:SignalP(1-30) AKAW2_50349A COG:S; EggNog:ENOG410PZ2P; InterPro:IPR022190; PFAM:PF12511 AKAW2_50351A COG:S; EggNog:ENOG410QEHG; InterPro:IPR025676; PFAM:PF14420 AKAW2_50352S COG:S; EggNog:ENOG410PW0A; InterPro:IPR001810,IPR036047; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_50353A SECRETED:SignalP(1-23) AKAW2_50354S COG:S; EggNog:ENOG410PK65 AKAW2_50355A COG:S; EggNog:ENOG410PQY4 AKAW2_50357S COG:S; EggNog:ENOG410PQZF AKAW2_50359S COG:S; EggNog:ENOG410PQ5R AKAW2_50362A COG:S; EggNog:ENOG410Q266 AKAW2_50364S COG:S; EggNog:ENOG410PKVH; SECRETED:SignalP(1-17) AKAW2_50365S COG:S; EggNog:ENOG410PV9A; InterPro:IPR003615; PFAM:PF13391 AKAW2_50366A InterPro:IPR009027,IPR011320,IPR037056; PFAM:PF01693 AKAW2_50367A COG:S; EggNog:ENOG410PMQ1; InterPro:IPR012337,IPR038717,IPR025959,IPR009057; PFAM:PF13358,PF13592 AKAW2_50370S COG:S; EggNog:ENOG410Q2ZJ AKAW2_50375S COG:B; EggNog:ENOG410PQ5M; InterPro:IPR009071,IPR036910; PFAM:PF00505 AKAW2_50377A COG:S; EggNog:ENOG410PMIB; InterPro:IPR016137,IPR036305; PFAM:PF00615; TransMembrane:7 (o22-44i51-69o89-106i152-173o205-224i236-260o272-292i) AKAW2_50379S COG:S; EggNog:ENOG410PGXJ; TransMembrane:4 (o24-43i50-71o77-97i109-127o) AKAW2_50380S COG:S; EggNog:ENOG410PGXJ; TransMembrane:2 (i12-33o45-65i) AKAW2_50383A COG:B; EggNog:ENOG410PQ5M; InterPro:IPR009071,IPR036910; PFAM:PF00505 AKAW2_50384A InterPro:IPR001138,IPR036864; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_50387S COG:Q; EggNog:ENOG410PPEB; InterPro:IPR036291,IPR002347; PFAM:PF08659,PF00106,PF13561; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_50391S COG:B; EggNog:ENOG410PQ5M; InterPro:IPR009071,IPR036910; PFAM:PF00505 AKAW2_50395S COG:S; EggNog:ENOG410Q266 AKAW2_50397S TransMembrane:1 (o60-78i) AKAW2_50399S COG:S; EggNog:ENOG410PQIG AKAW2_50402S COG:S; EggNog:ENOG410PN7M AKAW2_50403A COG:S; EggNog:ENOG410Q1UX; TransMembrane:1 (o178-195i) AKAW2_50404A SECRETED:SignalP(1-21); TransMembrane:1 (n3-14c19/20o463-483i) AKAW2_50405A TransMembrane:1 (i152-170o) AKAW2_50406A COG:S; EggNog:ENOG410PQIG AKAW2_50413A COG:S; EggNog:ENOG410PRBU; InterPro:IPR036236,IPR013087; PFAM:PF00096,PF12874 AKAW2_50414S COG:S; EggNog:ENOG410QDNC AKAW2_50416S COG:S; EggNog:ENOG410PT48 AKAW2_50417A COG:S; EggNog:ENOG410PJZ6; InterPro:IPR027417 AKAW2_50419A COG:S; EggNog:ENOG410PSQG; InterPro:IPR000999,IPR036389; TransMembrane:2 (o46-67i355-375o); go_function: GO:0004525 - ribonuclease III activity [Evidence IEA]; go_process: GO:0006396 - RNA processing [Evidence IEA] AKAW2_50420A COG:S; EggNog:ENOG410Q256; InterPro:IPR000999,IPR036389; go_function: GO:0004525 - ribonuclease III activity [Evidence IEA]; go_process: GO:0006396 - RNA processing [Evidence IEA] AKAW2_50421S COG:S; EggNog:ENOG410PPA6; InterPro:IPR012177,IPR039582,IPR023577,IPR033469; PFAM:PF01928; go_function: GO:0050333 - thiamin-triphosphatase activity [Evidence IEA]; go_process: GO:0006772 - thiamine metabolic process [Evidence IEA] AKAW2_50423S COG:S; EggNog:ENOG410Q2FG AKAW2_50424S COG:S; EggNog:ENOG410PHAM; InterPro:IPR029057,IPR000836,IPR027417,IPR036412, IPR023214; PFAM:PF12710,PF14681,PF13207; go_process: GO:0009116 - nucleoside metabolic process [Evidence IEA] AKAW2_50427A COG:S; EggNog:ENOG410PKSA; InterPro:IPR011009 AKAW2_50428A COG:S; EggNog:ENOG410PHD3; TransMembrane:4 (o6-25i32-51o57-73i186-211o) AKAW2_50431A COG:B; EggNog:ENOG410PQ5M; InterPro:IPR009071,IPR036910; PFAM:PF00505 AKAW2_50432S SECRETED:SignalP(1-21) AKAW2_50433S COG:S; EggNog:ENOG410PGXJ; TransMembrane:7 (o20-38i45-66o72-92i104-122o152-170i182-205o217-237i) AKAW2_50435A COG:S; EggNog:ENOG410Q1BA; InterPro:IPR039261; TransMembrane:1 (n3-11c16/17o26-50i) AKAW2_50436A COG:S; EggNog:ENOG410Q1BA; TransMembrane:2 (i32-51o87-109i) AKAW2_50437S SECRETED:SignalP(1-19) AKAW2_50438A COG:S; EggNog:ENOG410Q1HV; InterPro:IPR011009 AKAW2_50439S InterPro:IPR011009 AKAW2_50440A COG:S; EggNog:ENOG410Q1HV AKAW2_50441A COG:S; EggNog:ENOG410Q1HV; InterPro:IPR022198; PFAM:PF12520 AKAW2_50442S COG:S; EggNog:ENOG410PXU7 AKAW2_50443A COG:T; EggNog:ENOG410PWBG; InterPro:IPR000719,IPR011009,IPR017441; PFAM:PF00069; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_50444A InterPro:IPR016197,IPR000953 AKAW2_50445A COG:S; EggNog:ENOG410Q266 AKAW2_50447S COG:B; EggNog:ENOG410PQ5M; InterPro:IPR036910 AKAW2_50448A COG:S; EggNog:ENOG410PGXJ; TransMembrane:7 (o24-43i50-70o76-100i112-136o156-175i187-210o222-242i) AKAW2_50449S COG:S; EggNog:ENOG410PMIB; InterPro:IPR016137,IPR036305; PFAM:PF00615; TransMembrane:7 (o22-44i51-69o89-106i153-174o206-225i245-262o274-293i) AKAW2_50450S COG:S; EggNog:ENOG410PYN0 AKAW2_50451A TransMembrane:7 (o12-38i50-73o85-103i115-133o145-164i176-195o207-224i) AKAW2_50452S COG:O; EggNog:ENOG410PN65; InterPro:IPR001841,IPR016035,IPR002641,IPR017907; PFAM:PF01734; go_process: GO:0006629 - lipid metabolic process [Evidence IEA] AKAW2_50454S COG:S; EggNog:ENOG410PQVU AKAW2_50455S COG:S; EggNog:ENOG410Q1RI AKAW2_50456S COG:S; EggNog:ENOG410Q1RM; InterPro:IPR013087 AKAW2_50458S COG:S; EggNog:ENOG410PIBV; InterPro:IPR021858 AKAW2_50459A COG:S; EggNog:ENOG410PUUG; InterPro:IPR011009 AKAW2_50461A COG:S; EggNog:ENOG410PKA3; InterPro:IPR000477,IPR005135,IPR036691,IPR043502; PFAM:PF00078,PF14529 AKAW2_50463A COG:S; EggNog:ENOG410PV1W; InterPro:IPR011009; TransMembrane:1 (o630-648i) AKAW2_50467A COG:B; EggNog:ENOG410PQ5M; InterPro:IPR009071,IPR036910; PFAM:PF00505 AKAW2_50470A COG:S; EggNog:ENOG410Q2ZJ AKAW2_50472S SECRETED:SignalP(1-22) AKAW2_50474A COG:Q; EggNog:ENOG410PPEB; InterPro:IPR036291,IPR002347; PFAM:PF08659,PF00106,PF13561; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_50476S InterPro:IPR001138,IPR036864; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_50479S COG:S; EggNog:ENOG410PYHX AKAW2_50480S COG:S; EggNog:ENOG410Q1BA; InterPro:IPR039261; TransMembrane:6 (i42-63o75-95i107-126o138-157i169-186o192-216i) AKAW2_50482A COG:S; EggNog:ENOG410PGXJ; TransMembrane:7 (o20-38i50-68o74-95i107-131o151-169i181-198o218-237i) AKAW2_50484S COG:S; EggNog:ENOG410PMIB; TransMembrane:4 (o22-44i51-69o89-106i147-165o) AKAW2_50485S COG:S; EggNog:ENOG410PMIB; InterPro:IPR016137,IPR036305; PFAM:PF00615 AKAW2_50486S COG:S; EggNog:ENOG410PYN0 AKAW2_50487A TransMembrane:4 (n2-9c15/16o25-43i55-75o87-106i118-138o) AKAW2_50488S COG:O; EggNog:ENOG410PN65; InterPro:IPR001841,IPR016035,IPR002641,IPR017907; PFAM:PF01734; go_process: GO:0006629 - lipid metabolic process [Evidence IEA] AKAW2_50490S COG:S; EggNog:ENOG410Q1HV; InterPro:IPR022198; PFAM:PF12520 AKAW2_50491S COG:S; EggNog:ENOG410Q1HV AKAW2_50492A InterPro:IPR011009 AKAW2_50493A TransMembrane:1 (o20-39i) AKAW2_50496S COG:S; EggNog:ENOG410PQVU AKAW2_50497A COG:S; EggNog:ENOG410Q5D5 AKAW2_50498S COG:S; EggNog:ENOG410Q1RM; InterPro:IPR013087 AKAW2_50499S COG:S; EggNog:ENOG410PIBV; InterPro:IPR001138,IPR021858,IPR036864; PFAM:PF00172; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_50501A COG:S; EggNog:ENOG410PV1W AKAW2_50503S COG:S; EggNog:ENOG410Q0MK; InterPro:IPR009311; PFAM:PF06140; go_component: GO:0016021 - integral component of membrane [Evidence IEA] AKAW2_50504A COG:S; EggNog:ENOG410PXZA AKAW2_50505S COG:S; EggNog:ENOG410Q266 AKAW2_50508S COG:S; EggNog:ENOG410PQIG AKAW2_50510A COG:S; EggNog:ENOG410PH0I; InterPro:IPR022105,IPR022099; PFAM:PF12359 AKAW2_50511A COG:S; EggNog:ENOG410PH0I; InterPro:IPR022099; PFAM:PF12340 AKAW2_50512A COG:S; EggNog:ENOG410PH0I AKAW2_50513S COG:S; EggNog:ENOG410PXF7; InterPro:IPR027796; PFAM:PF14441 AKAW2_50514A COG:S; EggNog:ENOG410PZ88 AKAW2_50515A COG:S; EggNog:ENOG410Q0MK; InterPro:IPR009311; PFAM:PF06140; go_component: GO:0016021 - integral component of membrane [Evidence IEA] AKAW2_50516S COG:U; EggNog:ENOG410PITD; InterPro:IPR022812,IPR027417,IPR001401,IPR000375, IPR030381,IPR020850; PFAM:PF00350,PF01031,PF01926; go_function: GO:0003924 - GTPase activity [Evidence IEA]; go_function: GO:0005525 - GTP binding [Evidence IEA] AKAW2_50517S COG:L; EggNog:ENOG410PY1H; InterPro:IPR012337,IPR008906; PFAM:PF05699; go_function: GO:0046983 - protein dimerization activity [Evidence IEA] AKAW2_50519S COG:S; EggNog:ENOG410PT2C; InterPro:IPR000210,IPR011333; PFAM:PF00651; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_50520S COG:S; EggNog:ENOG410PPVJ AKAW2_50522S COG:Q; EggNog:ENOG410PPEB; InterPro:IPR036291,IPR002347; PFAM:PF08659,PF00106,PF13561; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_50525A SECRETED:SignalP(1-22) AKAW2_50532S COG:S; EggNog:ENOG410Q1BA; TransMembrane:7 (i18-35o41-63i75-95o107-126i138-159o165-184i196-215o) AKAW2_50533S InterPro:IPR039261 AKAW2_50535S COG:S; EggNog:ENOG410PV1W; InterPro:IPR011009; TransMembrane:1 (o598-616i) AKAW2_50536A COG:S; EggNog:ENOG410PT3Q; InterPro:IPR011333 AKAW2_50537S COG:T; EggNog:ENOG410PXX8; InterPro:IPR000210,IPR011333; PFAM:PF00651; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_50538S COG:M; EggNog:ENOG410Q1TJ; InterPro:IPR002110,IPR020683,IPR036770; PFAM:PF12796,PF00023,PF13637,PF13606; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_50539S COG:M; EggNog:ENOG410Q1TJ; InterPro:IPR002110,IPR036770,IPR020683; PFAM:PF13857,PF12796,PF00023,PF13637,PF13606; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_50540A COG:S; EggNog:ENOG410PPS6; TransMembrane:3 (i40-60o95-114i121-139o) AKAW2_50542A COG:S; EggNog:ENOG410Q1UX AKAW2_50544S COG:S; EggNog:ENOG410PKVH AKAW2_50545S COG:A; EggNog:ENOG410PIUX; InterPro:IPR036322,IPR027417,IPR007111,IPR015943, IPR001680,IPR019775,IPR020472,IPR031359,IPR017986; PFAM:PF00400,PF17100; TransMembrane:2 (o570-590i640-661o); go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_50546S COG:S; EggNog:ENOG410Q266 AKAW2_50548S COG:S; EggNog:ENOG410PHAM AKAW2_50549A COG:S; EggNog:ENOG410PVPZ; InterPro:IPR011009,IPR002575; PFAM:PF01636 AKAW2_50550A COG:S; EggNog:ENOG410PXJ0 AKAW2_50553A COG:S; EggNog:ENOG410PGXJ; TransMembrane:5 (i12-35o41-57i77-100o120-139i151-174o) AKAW2_50554S COG:S; EggNog:ENOG410PMIB; InterPro:IPR036305; TransMembrane:7 (o22-44i51-69o89-106i152-173o205-224i236-260o272-292i) AKAW2_50555S COG:S; EggNog:ENOG410PYN0 AKAW2_50556S COG:S; EggNog:ENOG410PXZA; InterPro:IPR011333 AKAW2_50557A COG:O; EggNog:ENOG410PN65; InterPro:IPR001841,IPR016035,IPR002641,IPR017907, IPR016181,IPR000182; PFAM:PF00583,PF01734; go_function: GO:0008080 - N-acetyltransferase activity [Evidence IEA]; go_process: GO:0006629 - lipid metabolic process [Evidence IEA] AKAW2_50559A COG:G; EggNog:ENOG410PH2N; InterPro:IPR029070,IPR017853,IPR001223; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_50560A COG:G; EggNog:ENOG410PH2N; InterPro:IPR017853,IPR001223,IPR001579; go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_50562A COG:S; EggNog:ENOG410PPS6; TransMembrane:1 (o74-94i) AKAW2_50563A InterPro:IPR011009 AKAW2_50564A COG:S; EggNog:ENOG410Q02D; SECRETED:SignalP(1-19) AKAW2_50565S COG:O; EggNog:ENOG410QE9I; InterPro:IPR002867,IPR017907,IPR031127,IPR044066, IPR013083; PFAM:PF01485; go_function: GO:0004842 - ubiquitin-protein transferase activity [Evidence IEA]; go_process: GO:0016567 - protein ubiquitination [Evidence IEA] AKAW2_50566A COG:L; EggNog:ENOG410PY1H; InterPro:IPR012337,IPR008906; PFAM:PF05699; go_function: GO:0046983 - protein dimerization activity [Evidence IEA] AKAW2_50567S TransMembrane:1 (i93-113o) AKAW2_50568A COG:S; EggNog:ENOG410PW63; InterPro:IPR021842; PFAM:PF11917 AKAW2_50569A COG:S; EggNog:ENOG410PW63 AKAW2_50570S COG:Q; EggNog:ENOG410PN2N; InterPro:IPR036291,IPR002347; PFAM:PF08659,PF00106,PF13561; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_50571S COG:O; EggNog:ENOG410PXE3; InterPro:IPR036610,IPR008914,IPR035810; MEROPS:MER0018285; PFAM:PF01161 AKAW2_50572A COG:Q; EggNog:ENOG410PXZF; InterPro:IPR000868,IPR036380; PFAM:PF00857 AKAW2_50573S COG:G; EggNog:ENOG410PFF2; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:10 (i43-64o84-102i109-128o134-156i168-190o196-218i285- 305o325-345i380-398o471-491i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_50575S COG:I; EggNog:ENOG410PV8S; InterPro:IPR002202,IPR023076,IPR023074,IPR009023, IPR009029; PFAM:PF00368; go_function: GO:0004420 - hydroxymethylglutaryl-CoA reductase (NADPH) activity [Evidence IEA]; go_function: GO:0016616 - oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Evidence IEA]; go_process: GO:0015936 - coenzyme A metabolic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_50576A COG:F,H; EggNog:ENOG410PF92; InterPro:IPR001248,IPR038271; PFAM:PF02133; TransMembrane:12 (i66-84o96-115i152-173o193-213i220-239o259-283i295- 318o349-370i393-417o423-441i461-483o503-523i); go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_50577S COG:Q; EggNog:ENOG410PKN1; InterPro:IPR026992,IPR027443,IPR005123; PFAM:PF03171,PF14226; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_50578A COG:Q; EggNog:ENOG410PG9N; InterPro:IPR013154,IPR013149,IPR002328,IPR036291, IPR011032; PFAM:PF00107,PF08240; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_50579A COG:S; EggNog:ENOG410PIKX; InterPro:IPR012292; PFAM:PF11563; go_function: GO:0019825 - oxygen binding [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA] AKAW2_50580S COG:I; EggNog:ENOG410PKBI; InterPro:IPR006091,IPR009075,IPR013786,IPR009100, IPR036250,IPR037069; PFAM:PF02770,PF00441,PF02771; go_function: GO:0016627 - oxidoreductase activity, acting on the CH-CH group of donors [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_50581S COG:F,H; EggNog:ENOG410PMN9; InterPro:IPR001248,IPR012681,IPR038271; PFAM:PF02133; TransMembrane:12 (i36-57o69-92i113-130o163-184i191-213o233-254i275-298o318- 337i358-375o387-407i430-450o462-484i); go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_50582A COG:E; EggNog:ENOG410PKIG; InterPro:IPR036526,IPR015942,IPR003010; PFAM:PF01177,PF00795; go_function: GO:0036361 - racemase activity, acting on amino acids and derivatives [Evidence IEA]; go_process: GO:0006807 - nitrogen compound metabolic process [Evidence IEA] AKAW2_50583S COG:F; EggNog:ENOG410PKDK; InterPro:IPR006680,IPR011059,IPR032466,IPR011778; MEROPS:MER0015112; PFAM:PF01979; go_component: GO:0005737 - cytoplasm [Evidence IEA]; go_function: GO:0016787 - hydrolase activity [Evidence IEA]; go_function: GO:0016810 - hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [Evidence IEA] AKAW2_50584A InterPro:IPR028144; PFAM:PF12734 AKAW2_50585A COG:S; EggNog:ENOG410QDET AKAW2_50586S COG:D,K,T; EggNog:ENOG410PICG; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i38-59o71-93i105-123o129-149i161-180o192-214i247-270o282- 302i314-332o338-361i373-394o406-424i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_50587A COG:Q; EggNog:ENOG410PGA3; InterPro:IPR000868,IPR036380; PFAM:PF00857; SECRETED:SignalP(1-19) AKAW2_50588A COG:S; EggNog:ENOG410PMZV; InterPro:IPR036851,IPR000028; PFAM:PF01328; SECRETED:SignalP(1-17); go_function: GO:0004601 - peroxidase activity [Evidence IEA] AKAW2_50591A COG:S; EggNog:ENOG410PK65 AKAW2_50592A COG:M; EggNog:ENOG410PKAU; InterPro:IPR002110,IPR027417,IPR007111,IPR036770, IPR020683; PFAM:PF05729,PF12796,PF00023,PF13637,PF13606; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_50593A COG:S; EggNog:ENOG410PYKN AKAW2_50594A COG:S; EggNog:ENOG410PRJR AKAW2_50595A COG:S; EggNog:ENOG410PT48 AKAW2_50596S COG:S; EggNog:ENOG410PGVQ; InterPro:IPR029063,IPR002877; PFAM:PF01728; go_function: GO:0008168 - methyltransferase activity [Evidence IEA]; go_process: GO:0032259 - methylation [Evidence IEA] AKAW2_50597S COG:S; EggNog:ENOG410PRVU AKAW2_50598S COG:S; EggNog:ENOG410PYMX AKAW2_50601A COG:S; EggNog:ENOG410Q1AW; InterPro:IPR009571; PFAM:PF06687; TransMembrane:3 (o110-130i142-164o184-208i); go_component: GO:0005886 - plasma membrane [Evidence IEA] AKAW2_50602S COG:M; EggNog:ENOG410PK0T; InterPro:IPR002110,IPR036770,IPR020683; PFAM:PF13857,PF12796,PF00023,PF13637,PF13606; TransMembrane:1 (o273-292i); go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_50603A COG:K; EggNog:ENOG410PKQ5; InterPro:IPR001005,IPR009057,IPR017877; PFAM:PF00249 AKAW2_50604A InterPro:IPR036428; go_function: GO:0008124 - 4-alpha-hydroxytetrahydrobiopterin dehydratase activity [Evidence IEA]; go_process: GO:0006729 - tetrahydrobiopterin biosynthetic process [Evidence IEA] AKAW2_50605A COG:S; EggNog:ENOG410PYNS; InterPro:IPR011990; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_50606S InterPro:IPR036864,IPR001138; PFAM:PF00172; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_50607S COG:S; EggNog:ENOG410PK6N AKAW2_50608S COG:S; EggNog:ENOG410PK6N AKAW2_50610S COG:S; EggNog:ENOG410PT2C; InterPro:IPR000210,IPR013087,IPR011333; PFAM:PF00651; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_50611S SECRETED:SignalP(1-18) AKAW2_50612S COG:S; EggNog:ENOG410PPVJ AKAW2_50615A COG:S; EggNog:ENOG410QDN7; InterPro:IPR000477,IPR036397,IPR012337,IPR005135, IPR002156,IPR036691,IPR043502; PFAM:PF00078,PF14529,PF00075; TransMembrane:1 (o1011-1030i); go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0004523 - RNA-DNA hybrid ribonuclease activity [Evidence IEA] AKAW2_50618A COG:S; EggNog:ENOG410PR07; InterPro:IPR011009 AKAW2_50619A TransMembrane:1 (o12-31i) AKAW2_50620A COG:S; EggNog:ENOG410PXZA AKAW2_50622S COG:S; EggNog:ENOG410QDN7; InterPro:IPR000477,IPR036397,IPR012337,IPR005135, IPR002156,IPR036691,IPR043502; PFAM:PF00078,PF14529,PF00075; TransMembrane:1 (o1011-1030i); go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0004523 - RNA-DNA hybrid ribonuclease activity [Evidence IEA] AKAW2_50623S COG:S; EggNog:ENOG410Q0MK; InterPro:IPR009311; PFAM:PF06140; go_component: GO:0016021 - integral component of membrane [Evidence IEA] AKAW2_50625A InterPro:IPR032549; PFAM:PF16297 AKAW2_50626A COG:M; EggNog:ENOG410PG00; InterPro:IPR002110,IPR036770,IPR011646,IPR020683; PFAM:PF13857,PF12796,PF00023,PF13637,PF13606; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_50627A COG:M; EggNog:ENOG410PF7T; InterPro:IPR035994; SECRETED:SignalP(1-25); go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_process: GO:0009116 - nucleoside metabolic process [Evidence IEA] AKAW2_50628S SECRETED:SignalP(1-21) AKAW2_50629S COG:M; EggNog:ENOG410PF7T; InterPro:IPR000845,IPR035994; PFAM:PF01048; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_process: GO:0009116 - nucleoside metabolic process [Evidence IEA] AKAW2_50630A COG:I; EggNog:ENOG410PMM4; InterPro:IPR023213,IPR001242; go_function: GO:0003824 - catalytic activity [Evidence IEA] AKAW2_50631A COG:E; EggNog:ENOG410Q9UP; InterPro:IPR008794; PFAM:PF05544 AKAW2_50632S COG:K; EggNog:ENOG410PRHZ; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_50633A COG:S; EggNog:ENOG410PMPA; InterPro:IPR036864,IPR021858,IPR001138; PFAM:PF00172,PF11951; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_50634A COG:O; EggNog:ENOG410PU84; InterPro:IPR011118 AKAW2_50635A COG:O; EggNog:ENOG410PWH7; InterPro:IPR011118 AKAW2_50636S COG:I; EggNog:ENOG410PHHA; InterPro:IPR019826,IPR002018,IPR029058; MEROPS:MER0030934; PFAM:PF00135; SECRETED:SignalP(1-18) AKAW2_50637A COG:E; EggNog:ENOG410PKJ4; InterPro:IPR024688,IPR018357,IPR011004,IPR001451; PFAM:PF14602,PF00132,PF12464; go_function: GO:0016407 - acetyltransferase activity [Evidence IEA]; go_function: GO:0016740 - transferase activity [Evidence IEA] AKAW2_50638A CAZy:GH13; COG:G; EggNog:ENOG410PGUZ; InterPro:IPR006047,IPR032091,IPR017853,IPR013780; PFAM:PF00128,PF16657; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_50640S COG:S; EggNog:ENOG410PXBI; InterPro:IPR036864,IPR021858,IPR001138; PFAM:PF00172,PF11951; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_50641S COG:G; EggNog:ENOG410QDJ5; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i48-73o85-108i120-138o144-162i174-194o206-226i277- 301o313-333i340-360o372-393i405-422o434-459i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_50642A COG:S; EggNog:ENOG410Q26X; TransMembrane:2 (o12-30i42-60o) AKAW2_50643S COG:S; EggNog:ENOG410PHYN; TransMembrane:7 (o22-38i50-73o108-126i138-160o180-203i215-238o250-270i) AKAW2_50644S COG:E; EggNog:ENOG410PF8W; InterPro:IPR004840,IPR004841,IPR004762; PFAM:PF13520,PF00324; TransMembrane:10 (i69-90o96-116i175-198o204-228i300-319o339-365i397- 415o427-453i474-497o503-520i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_process: GO:0006865 - amino acid transport [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_50645A COG:G; EggNog:ENOG410Q1QE; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i52-76o88-106i118-137o143-162i174-194o206-225i281- 299o319-337i358-376o388-405i417-442o454-473i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_50646S COG:S; EggNog:ENOG410PR3Q; InterPro:IPR038213,IPR009311; PFAM:PF06140; TransMembrane:1 (i104-122o); go_component: GO:0016021 - integral component of membrane [Evidence IEA] AKAW2_50647S COG:G; EggNog:ENOG410PFTW; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i56-77o89-111i123-140o146-169i181-204o216-241i289- 308o328-346i367-387o393-414i426-449o461-481i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_50648A COG:I; EggNog:ENOG410QEDZ; InterPro:IPR007312,IPR017850; PFAM:PF04185; TransMembrane:1 (i117-141o); go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0016788 - hydrolase activity, acting on ester bonds [Evidence IEA] AKAW2_50649A COG:S; EggNog:ENOG410PUW0; InterPro:IPR001138,IPR007219,IPR036864; PFAM:PF04082; TransMembrane:2 (i438-462o503-522i); antiSMASH:Cluster_5.3; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_50650S COG:Q; EggNog:ENOG410PUBF; InterPro:IPR034001,IPR043926,IPR027417,IPR003593, IPR010929,IPR017871,IPR029481,IPR003439,IPR013525, IPR034003; PFAM:PF01061,PF00005,PF06422,PF14510; SMCOG1000:ABC transporter ATP-binding protein; TransMembrane:13 (o495-517i529-551o571-594i606-628o634-656i746-763o1167- 1188i1200-1218o1238-1266i1287-1312o1318-1341i1353- 1371o1442-1460i); antiSMASH:Cluster_5.3; go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA]; go_function: GO:0042626 - ATPase-coupled transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_50651S COG:Q; EggNog:ENOG410PNCV; InterPro:IPR001613,IPR036188,IPR002937; PFAM:PF01593; antiSMASH:Cluster_5.3; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_50652S COG:I; EggNog:ENOG410PKH6; InterPro:IPR002921,IPR029058,IPR005592; PFAM:PF03893,PF01764; SECRETED:SignalP(1-19); antiSMASH:Cluster_5.3; go_process: GO:0006629 - lipid metabolic process [Evidence IEA]; go_process: GO:0016042 - lipid catabolic process [Evidence IEA] AKAW2_50653A COG:Q; EggNog:ENOG410PVR0; InterPro:IPR000868,IPR036380; PFAM:PF00857; antiSMASH:Cluster_5.3 AKAW2_50654S COG:G; EggNog:ENOG410PS5U; antiSMASH:Cluster_5.3 AKAW2_50655S COG:I; EggNog:ENOG410QD7I; InterPro:IPR032088,IPR016035,IPR001227,IPR014043, IPR016039,IPR014030,IPR014031,IPR020841; PFAM:PF00109,PF16073,PF02801; SMCOG1022:Beta-ketoacyl synthase; TransMembrane:3 (o80-99i111-131o137-153i); antiSMASH:Cluster_5.3; go_function: GO:0016740 - transferase activity [Evidence IEA]; go_function: GO:0016746 - transferase activity, transferring acyl groups [Evidence IEA] AKAW2_50656S COG:I; EggNog:ENOG410QD7I; InterPro:IPR016036,IPR030918,IPR016035,IPR001227, IPR014043,IPR020807,IPR042104; PFAM:PF14765; antiSMASH:Cluster_5.3; go_function: GO:0016740 - transferase activity [Evidence IEA] AKAW2_50657S COG:S; EggNog:ENOG410PTIR; antiSMASH:Cluster_5.3 AKAW2_50658A COG:Q; EggNog:ENOG410PJ8N; InterPro:IPR036188; PFAM:PF07992,PF13738; SMCOG1092:hypothetical protein; antiSMASH:Cluster_5.3 AKAW2_50659S COG:S; EggNog:ENOG410PUQC; TransMembrane:7 (o34-56i68-89o109-127i148-171o191-214i234-257o269-294i); antiSMASH:Cluster_5.3 AKAW2_50660S COG:I; EggNog:ENOG410PIK8; InterPro:IPR042098,IPR003819; antiSMASH:Cluster_5.3; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_50661A COG:S; EggNog:ENOG410PJQG; InterPro:IPR029063,IPR016461,IPR001077,IPR036390; PFAM:PF00891; SMCOG1042:O-methyltransferase; antiSMASH:Cluster_5.3; go_function: GO:0008168 - methyltransferase activity [Evidence IEA]; go_function: GO:0008171 - O-methyltransferase activity [Evidence IEA] AKAW2_50662A SECRETED:SignalP(1-22); antiSMASH:Cluster_5.3 AKAW2_50663S antiSMASH:Cluster_5.3 AKAW2_50664S COG:G; EggNog:ENOG410PHCB; InterPro:IPR011701,IPR036259; PFAM:PF07690; TransMembrane:6 (i12-32o81-100i147-167o179-200i212-233o239-265i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_50665A COG:S; EggNog:ENOG410PKHJ; InterPro:IPR007325,IPR037175; PFAM:PF04199; go_function: GO:0004061 - arylformamidase activity [Evidence IEA]; go_process: GO:0019441 - tryptophan catabolic process to kynurenine [Evidence IEA] AKAW2_50666A COG:S; EggNog:ENOG410PKAN; InterPro:IPR008547; PFAM:PF05705 AKAW2_50667S COG:G; EggNog:ENOG410PUT8; InterPro:IPR039556,IPR015813,IPR040442; PFAM:PF13714; go_function: GO:0003824 - catalytic activity [Evidence IEA] AKAW2_50668S COG:E; EggNog:ENOG410PJ7Z; InterPro:IPR005829,IPR005828,IPR003663,IPR036259, IPR020846; PFAM:PF00083,PF07690; TransMembrane:12 (i65-84o108-128i140-163o169-191i203-223o229-250i324- 349o361-382i389-407o419-439i460-481o487-508i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_50669S COG:S; EggNog:ENOG410Q0CR; InterPro:IPR027417,IPR006689; PFAM:PF00025; go_function: GO:0005525 - GTP binding [Evidence IEA] AKAW2_50670A COG:Q; EggNog:ENOG410PIRX; InterPro:IPR026992,IPR027443,IPR005123; PFAM:PF03171,PF14226; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_50671A COG:G; EggNog:ENOG410PFTW; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:10 (i72-92o112-131i143-167o228-248i285-308o328-351i372- 391o397-422i434-456o462-483i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_50672S COG:E; EggNog:ENOG410QEEZ; InterPro:IPR001613,IPR036188,IPR002937; PFAM:PF13450,PF01593; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_50673S COG:L; EggNog:ENOG410PRHW; InterPro:IPR012337,IPR002156,IPR036397; PFAM:PF00075; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0004523 - RNA-DNA hybrid ribonuclease activity [Evidence IEA] AKAW2_50674S COG:S; EggNog:ENOG410PHWY; InterPro:IPR039535,IPR011047; PFAM:PF05935,PF14269; TransMembrane:2 (i20-40o541-566i) AKAW2_50675S COG:C; EggNog:ENOG410PJGZ; InterPro:IPR029061,IPR033248,IPR009014,IPR005475; PFAM:PF02779,PF02780; SMCOG1110:1-deoxy-D-xylulose-5-phosphate synthase; antiSMASH:Cluster_5.4; go_function: GO:0003824 - catalytic activity [Evidence IEA] AKAW2_50676A COG:S; EggNog:ENOG410Q2C0; SECRETED:SignalP(1-21); antiSMASH:Cluster_5.4 AKAW2_50677A COG:S; EggNog:ENOG410PVFN; InterPro:IPR036864,IPR021858,IPR001138; PFAM:PF00172; antiSMASH:Cluster_5.4; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_50678S COG:S; EggNog:ENOG410PRZG; InterPro:IPR024652,IPR008949; PFAM:PF06330; antiSMASH:Cluster_5.4; go_function: GO:0016838 - carbon-oxygen lyase activity, acting on phosphates [Evidence IEA] AKAW2_50679S COG:G; EggNog:ENOG410PM6W; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; SMCOG1106:major facilitator transporter; TransMembrane:12 (i44-61o88-107i114-131o137-163i175-197o209-231i284- 303o315-334i346-367o373-393i405-427o433-459i); antiSMASH:Cluster_5.4; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_50680S COG:P; EggNog:ENOG410Q1HX; InterPro:IPR013099,IPR003280; PFAM:PF07885; TransMembrane:7 (n4-14c26/27o50-73i85-105o125-146i167-188o223-244i288- 309o350-380i); antiSMASH:Cluster_5.4; go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0005267 - potassium channel activity [Evidence IEA]; go_process: GO:0071805 - potassium ion transmembrane transport [Evidence IEA] AKAW2_50681S antiSMASH:Cluster_5.4 AKAW2_50682S COG:Q; EggNog:ENOG410PHHW; InterPro:IPR034001,IPR043926,IPR027417,IPR003593, IPR010929,IPR017871,IPR034003,IPR003439,IPR013525; PFAM:PF01061,PF00005,PF06422; TransMembrane:11 (o541-559i571-593o599-618i708-729o1127-1144i1151- 1172o1192-1223i1235-1256o1262-1284i1296-1316o1391-1409i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA]; go_function: GO:0042626 - ATPase-coupled transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_50684A TransMembrane:1 (o57-80i) AKAW2_50683S COG:S; EggNog:ENOG410QDH4; InterPro:IPR024528,IPR010619; PFAM:PF06738,PF12821; TransMembrane:10 (i520-538o544-563i575-595o607-629i641-665o685-703i710- 731o737-753i765-790o816-841i) AKAW2_50687S COG:S; EggNog:ENOG410Q252; InterPro:IPR002918,IPR029058; SECRETED:SignalP(1-18); go_function: GO:0016787 - hydrolase activity [Evidence IEA]; go_process: GO:0016042 - lipid catabolic process [Evidence IEA] AKAW2_50686A COG:G; EggNog:ENOG410QE2S; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i131-150o156-176i188-207o219-242i262-287o299-317i337- 360o375-396i403-420o432-454i466-489o539-561i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_50688S COG:S; EggNog:ENOG410PJV4; InterPro:IPR000073,IPR029058,IPR013595; MEROPS:MER0004231; PFAM:PF08386,PF00561; TransMembrane:1 (i27-44o) AKAW2_50689S COG:T,Z; EggNog:ENOG410PIQ8; InterPro:IPR036409,IPR001303; PFAM:PF00596 AKAW2_50690A COG:C; EggNog:ENOG410PWAB; InterPro:IPR036291,IPR029753,IPR006139,IPR006140; PFAM:PF00389; go_function: GO:0016616 - oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Evidence IEA]; go_function: GO:0051287 - NAD binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_50691A COG:S; EggNog:ENOG410Q2BB; TransMembrane:1 (o54-73i) AKAW2_50692S COG:S; EggNog:ENOG410PT8Q; InterPro:IPR029063 AKAW2_50693A COG:I; EggNog:ENOG410PHNM; InterPro:IPR042098,IPR003819; PFAM:PF02668; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_50694S COG:Q; EggNog:ENOG410PM5I; InterPro:IPR020946,IPR036188,IPR000960; PFAM:PF13738,PF13454,PF13450,PF07992; go_function: GO:0004499 - N,N-dimethylaniline monooxygenase activity [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_function: GO:0050661 - NADP binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_50695S COG:G; EggNog:ENOG410PHYX; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:11 (o45-63i119-136o142-159i180-202o214-234i281-303o323- 342i354-374o380-400i412-434o446-466i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_50696A SECRETED:SignalP(1-17); antiSMASH:Cluster_5.5 AKAW2_50697S COG:Q; EggNog:ENOG410PHE8; InterPro:IPR022313,IPR001106,IPR023144,IPR024083, IPR005922,IPR008948; PFAM:PF00221; antiSMASH:Cluster_5.5; go_component: GO:0005737 - cytoplasm [Evidence IEA]; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0016841 - ammonia-lyase activity [Evidence IEA]; go_process: GO:0006559 - L-phenylalanine catabolic process [Evidence IEA] AKAW2_50698A COG:S; EggNog:ENOG410PRZG; InterPro:IPR024652,IPR008949; PFAM:PF06330; antiSMASH:Cluster_5.5; go_function: GO:0016838 - carbon-oxygen lyase activity, acting on phosphates [Evidence IEA] AKAW2_50699S COG:S; EggNog:ENOG410PNYE; InterPro:IPR029058,IPR013595; MEROPS:MER0000441; PFAM:PF08386,PF00561; SECRETED:SignalP(1-23); antiSMASH:Cluster_5.5 AKAW2_50700S COG:S; EggNog:ENOG410PXQM; InterPro:IPR000210,IPR011333; PFAM:PF00651; antiSMASH:Cluster_5.5; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_50701S COG:I; EggNog:ENOG410PMTP; InterPro:IPR042098,IPR003819; PFAM:PF02668; SMCOG1121:dioxygenase, TauD/TfdA; antiSMASH:Cluster_5.5; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_50702A COG:G; EggNog:ENOG410Q1VM; InterPro:IPR005828,IPR003663,IPR036259,IPR020846; PFAM:PF00083,PF07690; SECRETED:SignalP(1-22); SMCOG1169:sugar transport protein; TransMembrane:9 (n11-23c28/29o64-84i91-109o121-139i151-169o181-202i330- 350o362-385i397-417o437-454i); antiSMASH:Cluster_5.7; go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_50703S InterPro:IPR021054; PFAM:PF12296; SECRETED:SignalP(1-23); antiSMASH:Cluster_5.7 AKAW2_50704S antiSMASH:Cluster_5.7 AKAW2_50705A COG:C; EggNog:ENOG410PK5V; InterPro:IPR013154,IPR013149,IPR036291,IPR011032, IPR020843; PFAM:PF00107,PF08240; SMCOG1028:crotonyl-CoA reductase / alcohol dehydrogenase; TransMembrane:1 (o20-41i); antiSMASH:Cluster_5.7; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_50706S antiSMASH:Cluster_5.7 AKAW2_50707S COG:I; EggNog:ENOG410PIJA; InterPro:IPR016036,IPR016035,IPR016039,IPR018201, IPR042104,IPR014030,IPR014031,IPR013968,IPR001227, IPR032821,IPR023213,IPR006162,IPR014043,IPR020806, IPR020807,IPR001242,IPR020841,IPR000873,IPR009081, IPR029063,IPR036736,IPR036291,IPR013217,IPR013120, IPR042099; PFAM:PF16197,PF00109,PF00668,PF00550,PF13489, PF13649,PF02801,PF00698,PF00501,PF07993,PF14765,PF08659, PF01370,PF08242,PF08241; SMCOG1022:Beta-ketoacyl synthase; antiSMASH:Cluster_5.7; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein] synthase activity [Evidence IEA]; go_function: GO:0016740 - transferase activity [Evidence IEA]; go_function: GO:0016746 - transferase activity, transferring acyl groups [Evidence IEA]; go_function: GO:0031177 - phosphopantetheine binding [Evidence IEA]; go_process: GO:0006633 - fatty acid biosynthetic process [Evidence IEA] AKAW2_50708A COG:S; EggNog:ENOG410PN3S; InterPro:IPR012674; antiSMASH:Cluster_5.7 AKAW2_50709S COG:S; EggNog:ENOG410PTE3; antiSMASH:Cluster_5.7 AKAW2_50710A COG:Q; EggNog:ENOG410PGYE; InterPro:IPR002402,IPR002974,IPR036396,IPR017972, IPR001128; PFAM:PF00067; SECRETED:SignalP(1-21); SMCOG1034:cytochrome P450; antiSMASH:Cluster_5.7; go_function: GO:0004497 - monooxygenase activity [Evidence IEA]; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0016712 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_50711S COG:S; EggNog:ENOG410PP5P; InterPro:IPR036864,IPR021858,IPR001138; PFAM:PF00172; antiSMASH:Cluster_5.7; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_50712A COG:I; EggNog:ENOG410PJB7; InterPro:IPR000873,IPR020845,IPR009081,IPR029063, IPR036736,IPR029058,IPR013217,IPR020806,IPR010071, IPR042099,IPR023213,IPR001242; PFAM:PF00501,PF08242,PF00668,PF08241,PF00550; SMCOG1127:condensation domain-containing protein; antiSMASH:Cluster_5.7; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0031177 - phosphopantetheine binding [Evidence IEA] AKAW2_50713S COG:S; EggNog:ENOG410PY37; TransMembrane:7 (o12-30i42-62o68-92i104-125o137-159i171-189o209-233i); antiSMASH:Cluster_5.6 AKAW2_50714S COG:S; EggNog:ENOG410PTR0; antiSMASH:Cluster_5.6 AKAW2_50715A COG:E; EggNog:ENOG410PJD8; InterPro:IPR015424,IPR002129,IPR015421; SMCOG1180:Decarboxylase, pyridoxal-dependent; antiSMASH:Cluster_5.6; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0016831 - carboxy-lyase activity [Evidence IEA]; go_function: GO:0030170 - pyridoxal phosphate binding [Evidence IEA]; go_process: GO:0019752 - carboxylic acid metabolic process [Evidence IEA] AKAW2_50716A SECRETED:SignalP(1-16); TransMembrane:1 (n3-14c19/20o55-72i); antiSMASH:Cluster_5.6 AKAW2_50717S COG:G; EggNog:ENOG410Q1Z0; InterPro:IPR005829,IPR005828,IPR003663,IPR036259, IPR020846; PFAM:PF00083,PF07690; SMCOG1169:sugar transport protein; TransMembrane:11 (o6-23i30-48o54-72i84-105o117-139i211-233o253-271i280- 301o321-341i353-374o386-406i); antiSMASH:Cluster_5.6; go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_50718A COG:Q; EggNog:ENOG410PP6F; InterPro:IPR026992,IPR027443,IPR005123; PFAM:PF03171,PF14226; antiSMASH:Cluster_5.6; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_50719A COG:Q; EggNog:ENOG410PN9I; InterPro:IPR000868,IPR036380; PFAM:PF00857; antiSMASH:Cluster_5.6 AKAW2_50720S COG:S; EggNog:ENOG410PQ3E; InterPro:IPR036864,IPR001138; PFAM:PF00172; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_50721S COG:O; EggNog:ENOG410PX8Y; InterPro:IPR016135,IPR023313,IPR000608; PFAM:PF00179 AKAW2_50722A COG:E; EggNog:ENOG410PFGY; InterPro:IPR001048,IPR041734,IPR004662,IPR036393, IPR011242,IPR006855; PFAM:PF04768,PF00696; go_component: GO:0005737 - cytoplasm [Evidence IEA]; go_function: GO:0003991 - acetylglutamate kinase activity [Evidence IEA]; go_process: GO:0006526 - arginine biosynthetic process [Evidence IEA] AKAW2_50723A COG:B; EggNog:ENOG410PK2I; InterPro:IPR001214; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_50724S COG:S; EggNog:ENOG410PSER; InterPro:IPR000182,IPR016181; PFAM:PF13673,PF13508,PF00583; go_function: GO:0008080 - N-acetyltransferase activity [Evidence IEA] AKAW2_50726A COG:K; EggNog:ENOG410Q1WU; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_50727A COG:M; EggNog:ENOG410PG3K; InterPro:IPR003333,IPR029063; PFAM:PF13649,PF08242,PF02353,PF08241,PF13489, PF13847; go_process: GO:0008610 - lipid biosynthetic process [Evidence IEA] AKAW2_50728S COG:H; EggNog:ENOG410PWB1; InterPro:IPR033749,IPR008949,IPR000092; PFAM:PF19086,PF00348; go_process: GO:0008299 - isoprenoid biosynthetic process [Evidence IEA] AKAW2_50729A COG:S; EggNog:ENOG410PMBR; InterPro:IPR014436,IPR004183; PFAM:PF02900; go_function: GO:0008198 - ferrous iron binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0016701 - oxidoreductase activity, acting on single donors with incorporation of molecular oxygen [Evidence IEA]; go_process: GO:0006725 - cellular aromatic compound metabolic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_50730S CAZy:GH28; COG:S; EggNog:ENOG410PK5D; InterPro:IPR000743,IPR012334,IPR011050; PFAM:PF00295; go_function: GO:0004650 - polygalacturonase activity [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_50731A COG:S; EggNog:ENOG410QEIG; InterPro:IPR036188,IPR002938; TransMembrane:1 (i20-42o); go_function: GO:0071949 - FAD binding [Evidence IEA] AKAW2_50732S CAZy:CE10; COG:V; EggNog:ENOG410PJWW; InterPro:IPR029058,IPR013094; MEROPS:MER0034665; PFAM:PF07859; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_50733A COG:S; EggNog:ENOG410PUUJ; InterPro:IPR036864,IPR021858,IPR001138; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_50735S COG:I; EggNog:ENOG410PG5V; InterPro:IPR016039,IPR020610,IPR020617,IPR020616, IPR020615,IPR002155; PFAM:PF00108,PF02803; go_function: GO:0016746 - transferase activity, transferring acyl groups [Evidence IEA]; go_function: GO:0016747 - transferase activity, transferring acyl groups other than amino-acyl groups [Evidence IEA] AKAW2_50736A COG:C; EggNog:ENOG410PH7W; InterPro:IPR015590,IPR016161,IPR016162,IPR016163; PFAM:PF00171; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0016620 - oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_50737A COG:S; EggNog:ENOG410PI5E; InterPro:IPR003497,IPR000073,IPR029058,IPR011008; MEROPS:MER0033259; PFAM:PF12146,PF00561,PF12697 AKAW2_50738S COG:S; EggNog:ENOG410PINJ; InterPro:IPR024461; PFAM:PF07798; TransMembrane:1 (o286-307i) AKAW2_50739S COG:S; EggNog:ENOG410PKK1; InterPro:IPR021102; PFAM:PF12222; SECRETED:SignalP(1-21) AKAW2_50740A COG:C,H; EggNog:ENOG410PGID; InterPro:IPR036188,IPR002938,IPR036249,IPR038220, IPR012941; PFAM:PF07976,PF01494; TransMembrane:1 (i12-32o); go_function: GO:0071949 - FAD binding [Evidence IEA] AKAW2_50741A COG:S; EggNog:ENOG410PNEC; InterPro:IPR036864,IPR001138; PFAM:PF00172; TransMembrane:1 (o644-662i); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_50742S COG:C; EggNog:ENOG410PI0H; InterPro:IPR018108,IPR023395; PFAM:PF00153; TransMembrane:2 (i84-107o127-150i); antiSMASH:Cluster_5.8 AKAW2_50743A BUSCO:EOG092624X0; COG:V; EggNog:ENOG410PHKJ; InterPro:IPR006093,IPR006094,IPR010031,IPR036318, IPR016169,IPR030654,IPR007173,IPR016167,IPR016166; PFAM:PF04030,PF01565; SMCOG1138:FAD linked oxidase domain protein; antiSMASH:Cluster_5.8; go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0003885 - D-arabinono-1,4-lactone oxidase activity [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0016899 - oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_function: GO:0071949 - FAD binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_50744A BUSCO:EOG09262G8Y; COG:P; EggNog:ENOG410QE9V; InterPro:IPR027417,IPR003593,IPR003439; SMCOG1288:ABC transporter related protein; antiSMASH:Cluster_5.8; go_function: GO:0005524 - ATP binding [Evidence IEA] AKAW2_50745S COG:G; EggNog:ENOG410Q22Q; InterPro:IPR028356,IPR028357,IPR036220,IPR036291, IPR001732,IPR014027,IPR014026,IPR017476,IPR008927; PFAM:PF00984,PF03720; SECRETED:SignalP(1-19); SMCOG1152:nucleotide sugar dehydrogenase; antiSMASH:Cluster_5.8; go_function: GO:0003979 - UDP-glucose 6-dehydrogenase activity [Evidence IEA]; go_function: GO:0016616 - oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Evidence IEA]; go_function: GO:0051287 - NAD binding [Evidence IEA]; go_process: GO:0000271 - polysaccharide biosynthetic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_50746S COG:S; EggNog:ENOG410PS59; InterPro:IPR022085; PFAM:PF12311; antiSMASH:Cluster_5.8 AKAW2_50747A COG:S; EggNog:ENOG410PKRC; TransMembrane:2 (i73-93o136-154i); antiSMASH:Cluster_5.8 AKAW2_50748S COG:S; EggNog:ENOG410PMXJ; InterPro:IPR011990,IPR040201; TransMembrane:1 (i88-109o); antiSMASH:Cluster_5.8; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_50749S COG:S; EggNog:ENOG410PU4B; antiSMASH:Cluster_5.8 AKAW2_50750A COG:I; EggNog:ENOG410PFB6; InterPro:IPR000873,IPR020845,IPR009081,IPR006162, IPR036736,IPR020806,IPR010071,IPR042099,IPR023213, IPR001242; PFAM:PF00501,PF00668,PF00550; SMCOG1127:condensation domain-containing protein; antiSMASH:Cluster_5.8; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0031177 - phosphopantetheine binding [Evidence IEA] AKAW2_50751S COG:S; EggNog:ENOG410PKVD; InterPro:IPR013744,IPR029058; PFAM:PF08538; TransMembrane:1 (i410-428o); antiSMASH:Cluster_5.8 AKAW2_50752A COG:J; EggNog:ENOG410PGG3; InterPro:IPR019432,IPR016181; PFAM:PF13523; SMCOG1203:putative siderophore biosynthesis protein; antiSMASH:Cluster_5.8; go_function: GO:0016746 - transferase activity, transferring acyl groups [Evidence IEA]; go_process: GO:0019290 - siderophore biosynthetic process [Evidence IEA] AKAW2_50753S COG:I; EggNog:ENOG410PKIY; InterPro:IPR001753,IPR029045; PFAM:PF16113,PF00378; SMCOG1023:enoyl-CoA hydratase; antiSMASH:Cluster_5.8; go_function: GO:0003824 - catalytic activity [Evidence IEA] AKAW2_50754S COG:G; EggNog:ENOG410PGZU; InterPro:IPR020846,IPR011701,IPR036259,IPR010573; PFAM:PF07690; SMCOG1005:Drug resistance transporter, EmrB/QacA; TransMembrane:14 (i79-97o117-137i149-171o177-194i206-223o235-255i281- 305o317-342i354-376o396-418i425-444o450-480i487-511o565- 583i); antiSMASH:Cluster_5.8; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_50755A COG:S; EggNog:ENOG410PU14; TransMembrane:1 (i7-26o); antiSMASH:Cluster_5.8 AKAW2_50756A COG:S; EggNog:ENOG410PU14; InterPro:IPR007269; PFAM:PF04140,PF04191; TransMembrane:5 (o6-24i45-72o105-125i161-178o198-217i); antiSMASH:Cluster_5.8; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0004671 - protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity [Evidence IEA]; go_process: GO:0006481 - C-terminal protein methylation [Evidence IEA] AKAW2_50757S COG:S; EggNog:ENOG410PRMR; antiSMASH:Cluster_5.8 AKAW2_50758A COG:K; EggNog:ENOG410PHBZ; InterPro:IPR016181,IPR000182,IPR015416; PFAM:PF09337,PF00583,PF17921; antiSMASH:Cluster_5.8; go_function: GO:0008080 - N-acetyltransferase activity [Evidence IEA] AKAW2_50759S BUSCO:EOG09261CM0; COG:A; EggNog:ENOG410PGMY; InterPro:IPR027417,IPR014001,IPR001650,IPR006935; PFAM:PF00271,PF00270,PF04851; SMCOG1122:ATP-dependent RNA helicase; antiSMASH:Cluster_5.8; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_50760A COG:Q; EggNog:ENOG410PJUU; InterPro:IPR017871,IPR027417,IPR003593,IPR039421, IPR011527,IPR003439,IPR036640; PFAM:PF00005,PF00664; TransMembrane:12 (i24-48o80-104i155-174o180-201i257-280o300-327i731- 757o777-803i847-872o878-902i961-983o995-1018i); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA]; go_function: GO:0042626 - ATPase-coupled transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_50762S COG:C; EggNog:ENOG410PGV2; InterPro:IPR036188,IPR015904,IPR023753; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_50763A COG:S; EggNog:ENOG410PJMI; InterPro:IPR029032 AKAW2_50764A BUSCO:EOG09262H1X; COG:Q; EggNog:ENOG410PG30; InterPro:IPR012999,IPR023753,IPR001100,IPR004099, IPR036188,IPR006322,IPR016156; PFAM:PF02852,PF13738,PF07992,PF00070; go_function: GO:0004362 - glutathione-disulfide reductase activity [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0016668 - oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_function: GO:0050661 - NADP binding [Evidence IEA]; go_process: GO:0006749 - glutathione metabolic process [Evidence IEA]; go_process: GO:0045454 - cell redox homeostasis [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_50765A COG:S; EggNog:ENOG410PX7I AKAW2_50766S SECRETED:SignalP(1-25) AKAW2_50767A SECRETED:SignalP(1-25) AKAW2_50768S COG:G; EggNog:ENOG410PJHW; InterPro:IPR000760,IPR020583,IPR020550,IPR033942; PFAM:PF00459; go_function: GO:0008934 - inositol monophosphate 1-phosphatase activity [Evidence IEA]; go_process: GO:0046854 - phosphatidylinositol phosphorylation [Evidence IEA]; go_process: GO:0046855 - inositol phosphate dephosphorylation [Evidence IEA] AKAW2_50769A COG:E; EggNog:ENOG410PKCS; InterPro:IPR036291,IPR013708; PFAM:PF08501; go_function: GO:0004764 - shikimate 3-dehydrogenase (NADP+) activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_50770S BUSCO:EOG092641G3; COG:L; EggNog:ENOG410PICN; InterPro:IPR009061,IPR022656,IPR037129,IPR000465; PFAM:PF05181; go_function: GO:0003684 - damaged DNA binding [Evidence IEA]; go_process: GO:0006289 - nucleotide-excision repair [Evidence IEA] AKAW2_50771A COG:P; EggNog:ENOG410PNV3; InterPro:IPR036874,IPR015892,IPR001765; PFAM:PF00484; go_function: GO:0004089 - carbonate dehydratase activity [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0015976 - carbon utilization [Evidence IEA] AKAW2_50772A CAZy:GH1; COG:G; EggNog:ENOG410PKAP; InterPro:IPR033132,IPR017853,IPR001360; PFAM:PF00232; go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_50773S CAZy:AA1; COG:Q; EggNog:ENOG410PJMK; InterPro:IPR008972,IPR001117,IPR011706,IPR033138, IPR002355,IPR011707; PFAM:PF00394,PF07731,PF07732; SECRETED:SignalP(1-23); go_function: GO:0005507 - copper ion binding [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_50774S COG:S; EggNog:ENOG410Q2T4; SECRETED:SignalP(1-21) AKAW2_50775A COG:S; EggNog:ENOG410PK4I; InterPro:IPR039896,IPR012916; PFAM:PF07808 AKAW2_50776S BUSCO:EOG09261M4S; COG:I; EggNog:ENOG410PHHY; InterPro:IPR013698,IPR040125,IPR036188,IPR006076; PFAM:PF08491; TransMembrane:5 (i28-47o372-389i401-421o427-443i455-475o); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0004506 - squalene monooxygenase activity [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_process: GO:0016126 - sterol biosynthetic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_50777A COG:D; EggNog:ENOG410PG71; InterPro:IPR002058,IPR043519; PFAM:PF19088,PF03828 AKAW2_50779S COG:S; EggNog:ENOG410PWUW AKAW2_50780A COG:S; EggNog:ENOG410PQYN; InterPro:IPR000073,IPR029058; PFAM:PF12697 AKAW2_50781A COG:E,G; EggNog:ENOG410PHPB; InterPro:IPR009262; PFAM:PF06027; TransMembrane:9 (o67-92i104-123o135-154i166-183o189-208i229-249o290- 312i319-339o345-364i); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_50782S BUSCO:EOG09262D0D; COG:G; EggNog:ENOG410PFTV; InterPro:IPR016024,IPR006887,IPR011993; PFAM:PF04802 AKAW2_50783S COG:S; EggNog:ENOG410PPWA; InterPro:IPR019363,IPR029058; PFAM:PF12697,PF10230; TransMembrane:2 (o34-56i197-215o) AKAW2_50784A COG:S; EggNog:ENOG410PQW4; InterPro:IPR010334,IPR011993; PFAM:PF06058; go_function: GO:0008047 - enzyme activator activity [Evidence IEA]; go_process: GO:0000290 - deadenylation-dependent decapping of nuclear-transcribed mRNA [Evidence IEA]; go_process: GO:0043085 - positive regulation of catalytic activity [Evidence IEA] AKAW2_50785S COG:U; EggNog:ENOG410QDDJ; InterPro:IPR013783,IPR000300,IPR036691; go_process: GO:0046856 - phosphatidylinositol dephosphorylation [Evidence IEA] AKAW2_50786A COG:S; EggNog:ENOG410PJ17; TransMembrane:4 (o91-109i116-134o204-224i396-421o) AKAW2_50788S COG:T; EggNog:ENOG410PJEA; InterPro:IPR001499; PFAM:PF02076; TransMembrane:8 (o12-32i44-63o83-103i124-145o165-191i220-245o275-293i300- 318o); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0004932 - mating-type factor pheromone receptor activity [Evidence IEA]; go_process: GO:0007186 - G protein-coupled receptor signaling pathway [Evidence IEA] AKAW2_50789A BUSCO:EOG09265JNA; COG:S; EggNog:ENOG410Q0S7; InterPro:IPR011344,IPR012340,IPR000424; PFAM:PF00436; go_function: GO:0003697 - single-stranded DNA binding [Evidence IEA]; go_process: GO:0006260 - DNA replication [Evidence IEA] AKAW2_50790S COG:S; EggNog:ENOG410PHIW; InterPro:IPR025256; PFAM:PF13886; SECRETED:SignalP(1-16); TransMembrane:7 (n3-14c21/22o112-132i139-159o165-189i196-212o224-240i247- 265o305-323i) AKAW2_50791A COG:D,U; EggNog:ENOG410PH1S; InterPro:IPR005062; PFAM:PF03399 AKAW2_50792A COG:S; EggNog:ENOG410PM7R; InterPro:IPR021264; PFAM:PF11001 AKAW2_50793A COG:Q; EggNog:ENOG410PFBG; InterPro:IPR017871,IPR027417,IPR003593,IPR011527, IPR003439,IPR036640; PFAM:PF00005,PF00664; TransMembrane:13 (o59-80i92-114o129-148i160-179o191-211i342-367o443- 465i531-553o565-589i966-989o1009-1036i1095-1121o1199- 1222i); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA]; go_function: GO:0042626 - ATPase-coupled transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_50794S BUSCO:EOG09262BCZ; COG:S; EggNog:ENOG410PGAY; InterPro:IPR041175,IPR020683,IPR036770; PFAM:PF18826,PF13857 AKAW2_50795S COG:T; EggNog:ENOG410PMSK; InterPro:IPR000719,IPR011009,IPR008271; PFAM:PF07714,PF00069; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_50796S COG:S; EggNog:ENOG410PNDI AKAW2_50797A COG:U; EggNog:ENOG410PHH4; InterPro:IPR043512,IPR022775,IPR001392,IPR011012, IPR036168,IPR043532,IPR028565; PFAM:PF01217,PF00928; TransMembrane:1 (o394-413i); go_component: GO:0030131 - clathrin adaptor complex [Evidence IEA]; go_process: GO:0006886 - intracellular protein transport [Evidence IEA]; go_process: GO:0016192 - vesicle-mediated transport [Evidence IEA] AKAW2_50798A COG:S; EggNog:ENOG410PN63; InterPro:IPR019383; PFAM:PF10256 AKAW2_50799S COG:E; EggNog:ENOG410PKBZ; InterPro:IPR036526,IPR039703,IPR003010; PFAM:PF00795; go_function: GO:0008418 - protein-N-terminal asparagine amidohydrolase activity [Evidence IEA]; go_function: GO:0070773 - protein-N-terminal glutamine amidohydrolase activity [Evidence IEA]; go_process: GO:0006807 - nitrogen compound metabolic process [Evidence IEA] AKAW2_50800S BUSCO:EOG09263P17; COG:K; EggNog:ENOG410PNSV; InterPro:IPR011598,IPR036638; PFAM:PF00010; go_function: GO:0046983 - protein dimerization activity [Evidence IEA] AKAW2_50801A CAZy:CBM63; COG:G; EggNog:ENOG410PN6V; InterPro:IPR036908,IPR007112,IPR009009,IPR036749; PFAM:PF03330; SECRETED:SignalP(1-22) AKAW2_50802A COG:U; EggNog:ENOG410PGD6; InterPro:IPR039682,IPR007191; PFAM:PF04048; go_component: GO:0000145 - exocyst [Evidence IEA]; go_process: GO:0006904 - vesicle docking involved in exocytosis [Evidence IEA]; go_process: GO:0090522 - vesicle tethering involved in exocytosis [Evidence IEA] AKAW2_50803A COG:E; EggNog:ENOG410PFDG; InterPro:IPR000994,IPR033740,IPR000587,IPR029149, IPR032416,IPR001131,IPR036005; MEROPS:MER0016544; PFAM:PF16188,PF16189,PF01321,PF00557; go_function: GO:0016787 - hydrolase activity [Evidence IEA]; go_function: GO:0070006 - metalloaminopeptidase activity [Evidence IEA] AKAW2_50804S COG:U,Y; EggNog:ENOG410PFB1; InterPro:IPR016024,IPR011989,IPR040520,IPR001494; PFAM:PF03810,PF18806; go_function: GO:0008536 - Ran GTPase binding [Evidence IEA]; go_process: GO:0006886 - intracellular protein transport [Evidence IEA] AKAW2_50805S COG:S; EggNog:ENOG410PKDB; InterPro:IPR018306; PFAM:PF10544,PF13455 AKAW2_50806A TransMembrane:3 (o6-28i35-59o65-92i) AKAW2_50807A BUSCO:EOG09263MIB; COG:H; EggNog:ENOG410PI0Y; InterPro:IPR011060,IPR013785,IPR001852,IPR033755; PFAM:PF01680; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_process: GO:0042819 - vitamin B6 biosynthetic process [Evidence IEA]; go_process: GO:0042823 - pyridoxal phosphate biosynthetic process [Evidence IEA] AKAW2_50809S COG:S; EggNog:ENOG410PSED; TransMembrane:1 (n2-13c18/19o97-124i) AKAW2_50808A COG:L; EggNog:ENOG410PIIK; InterPro:IPR007220; PFAM:PF04084; go_component: GO:0000808 - origin recognition complex [Evidence IEA]; go_component: GO:0005634 - nucleus [Evidence IEA]; go_process: GO:0006260 - DNA replication [Evidence IEA] AKAW2_50810S BUSCO:EOG09262528; COG:E; EggNog:ENOG410PH6D; InterPro:IPR042195,IPR016117,IPR002813; MEROPS:MER0011829; PFAM:PF01960; go_function: GO:0004358 - glutamate N-acetyltransferase activity [Evidence IEA]; go_process: GO:0006526 - arginine biosynthetic process [Evidence IEA] AKAW2_50811A BUSCO:EOG092620E4; COG:O,U; EggNog:ENOG410PX0Y; InterPro:IPR019561,IPR023201,IPR030659,IPR002208; PFAM:PF10559,PF00344; TransMembrane:10 (i33-55o75-100i120-139o145-167i174-195o244-265i285- 311o359-380i416-434o440-458i); go_component: GO:0016020 - membrane [Evidence IEA]; go_process: GO:0015031 - protein transport [Evidence IEA] AKAW2_50812A COG:S; EggNog:ENOG410PRFM AKAW2_50813S COG:D; EggNog:ENOG410PI3V; InterPro:IPR036915,IPR043198; go_function: GO:0016538 - cyclin-dependent protein serine/threonine kinase regulator activity [Evidence IEA]; go_process: GO:0006357 - regulation of transcription by RNA polymerase II [Evidence IEA] AKAW2_50814S BUSCO:EOG09263WZ2; COG:U; EggNog:ENOG410PIIC; InterPro:IPR007135; PFAM:PF03987 AKAW2_50815A COG:S; EggNog:ENOG410PTZQ; SECRETED:SignalP(1-22) AKAW2_50816A COG:S; EggNog:ENOG410PTZQ AKAW2_50817A COG:S; EggNog:ENOG410Q1IV; InterPro:IPR038883 AKAW2_50818A BUSCO:EOG09264B2P; CAZy:GT2_Glycos_transf; COG:M; EggNog:ENOG410PH9P; InterPro:IPR001173,IPR029044,IPR035518; PFAM:PF00535; TransMembrane:2 (o24-47i396-415o) AKAW2_50819A COG:S; EggNog:ENOG410PHB6; InterPro:IPR018834,IPR011990; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_50820A COG:O; EggNog:ENOG410PY8Y; InterPro:IPR001841,IPR013083; PFAM:PF13920 AKAW2_50821S COG:L; EggNog:ENOG410PNH9; InterPro:IPR015797,IPR000086; PFAM:PF00293; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_50822A COG:L; EggNog:ENOG410PJH1; InterPro:IPR020084,IPR000086,IPR015797; PFAM:PF00293; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_50823A COG:E; EggNog:ENOG410PFSR; InterPro:IPR000581,IPR004404,IPR037237,IPR042096, IPR020558; PFAM:PF00920; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0004160 - dihydroxy-acid dehydratase activity [Evidence IEA]; go_process: GO:0009082 - branched-chain amino acid biosynthetic process [Evidence IEA] AKAW2_50824A COG:S; EggNog:ENOG410PJGF; InterPro:IPR041492,IPR006439,IPR023198,IPR036412, IPR023214; PFAM:PF00702,PF13419; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_50825S BUSCO:EOG09261N2L; COG:A; EggNog:ENOG410PIAH; InterPro:IPR033421,IPR033449,IPR007306; PFAM:PF04179,PF17184; go_function: GO:0043399 - tRNA A64-2'-O-ribosylphosphate transferase activity [Evidence IEA]; go_process: GO:0019988 - charged-tRNA amino acid modification [Evidence IEA] AKAW2_50826A COG:S; EggNog:ENOG410PIJJ; InterPro:IPR018170,IPR020471,IPR036812,IPR023210; PFAM:PF00248; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_50827S COG:Z; EggNog:ENOG410PIF3; InterPro:IPR011992,IPR002048,IPR014837,IPR001715, IPR001589,IPR036872; PFAM:PF08726,PF00307,PF11971; go_function: GO:0005509 - calcium ion binding [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_50828S COG:A; EggNog:ENOG410PQ3J; InterPro:IPR000504,IPR025715,IPR035979,IPR012677; PFAM:PF13865,PF00076; go_function: GO:0003676 - nucleic acid binding [Evidence IEA] AKAW2_50829A COG:I; EggNog:ENOG410Q597; InterPro:IPR036322,IPR015943,IPR019775,IPR001680, IPR017986; PFAM:PF00400; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_50830S BUSCO:EOG09261B3Q; COG:I; EggNog:ENOG410PHA6; InterPro:IPR011989,IPR013535,IPR036322,IPR038122, IPR015943,IPR015155,IPR019775,IPR001680,IPR020472, IPR017986; PFAM:PF09070,PF00400,PF08324; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_50831A BUSCO:EOG09264GQZ; COG:G; EggNog:ENOG410PJKF; InterPro:IPR036652,IPR032976,IPR004443; PFAM:PF03853 AKAW2_50832S BUSCO:EOG092652YI; COG:J; EggNog:ENOG410PQME; InterPro:IPR023803,IPR000307; PFAM:PF00886; go_component: GO:0005840 - ribosome [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_process: GO:0006412 - translation [Evidence IEA] AKAW2_50834S COG:A; EggNog:ENOG410QDTE; InterPro:IPR000504,IPR012677,IPR035979; PFAM:PF00076; go_function: GO:0003676 - nucleic acid binding [Evidence IEA] AKAW2_50835S TransMembrane:2 (i7-28o34-54i) AKAW2_50836S COG:S; EggNog:ENOG410PPA3; InterPro:IPR021036; PFAM:PF12298 AKAW2_50837A BUSCO:EOG09260FFP; COG:T; EggNog:ENOG410PJ9V; InterPro:IPR001789,IPR011006; PFAM:PF00072; go_process: GO:0000160 - phosphorelay signal transduction system [Evidence IEA] AKAW2_50838A COG:S; EggNog:ENOG410PFVU; InterPro:IPR006603; PFAM:PF04193; TransMembrane:8 (i7-26o46-68i80-99o111-127i139-159o171-190i202-223o229- 252i) AKAW2_50839A COG:T; EggNog:ENOG410PI8G; InterPro:IPR039644,IPR035522,IPR036028,IPR001452; PFAM:PF00018,PF07653; TransMembrane:4 (i32-56o68-87i99-120o126-146i); go_function: GO:0005034 - osmosensor activity [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_50840A COG:S; EggNog:ENOG410PQ15; InterPro:IPR009991; PFAM:PF07426; go_component: GO:0005869 - dynactin complex [Evidence IEA]; go_process: GO:0061640 - cytoskeleton-dependent cytokinesis [Evidence IEA] AKAW2_50841A COG:S; EggNog:ENOG410PN3D; InterPro:IPR009060; PFAM:PF14555; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_50842S BUSCO:EOG09261IOS; COG:T; EggNog:ENOG410PGMD; InterPro:IPR017441,IPR032270,IPR008271,IPR028375, IPR000719,IPR011009,IPR013896; PFAM:PF16579,PF07714,PF08587,PF00069; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0004674 - protein serine/threonine kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_50843S COG:S; EggNog:ENOG410PRMF; InterPro:IPR007219; PFAM:PF04082; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA] AKAW2_50844A COG:G; EggNog:ENOG410PV9J; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:11 (o30-50i57-74o86-104i116-139o145-165i248-273o293-315i336- 357o363-387i399-419o431-451i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_50845S COG:C,H; EggNog:ENOG410PH8B; InterPro:IPR036188,IPR002938; PFAM:PF01494; go_function: GO:0071949 - FAD binding [Evidence IEA] AKAW2_50846A COG:S; EggNog:ENOG410PMIH; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_50847A COG:S; EggNog:ENOG410PMIH; InterPro:IPR014710,IPR011051,IPR013096; PFAM:PF07883 AKAW2_50848A COG:T; EggNog:ENOG410PS8E; InterPro:IPR008984,IPR000253; PFAM:PF00498; TransMembrane:1 (o649-674i); go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_50849A COG:U; EggNog:ENOG410PFH4; InterPro:IPR011990,IPR019734,IPR005687,IPR013026, IPR001440; PFAM:PF07719,PF00515,PF13176,PF13181,PF13414, PF13432; TransMembrane:1 (i42-63o); go_component: GO:0005741 - mitochondrial outer membrane [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_function: GO:0015450 - P-P-bond-hydrolysis-driven protein transmembrane transporter activity [Evidence IEA]; go_process: GO:0006886 - intracellular protein transport [Evidence IEA] AKAW2_50850S COG:E; EggNog:ENOG410PNK8; InterPro:IPR036038,IPR001544,IPR043131,IPR043132; PFAM:PF01063; go_function: GO:0003824 - catalytic activity [Evidence IEA] AKAW2_50851S COG:U; EggNog:ENOG410PNN0; InterPro:IPR006797,IPR037365; PFAM:PF04707; go_component: GO:0005758 - mitochondrial intermembrane space [Evidence IEA] AKAW2_50852S COG:S; EggNog:ENOG410PYI8 AKAW2_50853S COG:S; EggNog:ENOG410PZ4C; SECRETED:SignalP(1-30); TransMembrane:1 (n14-25c30/31o182-205i) AKAW2_50854A COG:S; EggNog:ENOG410PN4P; InterPro:IPR012674,IPR008729; PFAM:PF05870; go_function: GO:0016831 - carboxy-lyase activity [Evidence IEA] AKAW2_50855S COG:U; EggNog:ENOG410PSG0; InterPro:IPR008253; PFAM:PF01284; TransMembrane:4 (i12-34o40-59i71-93o130-150i); antiSMASH:Cluster_5.9; go_component: GO:0016020 - membrane [Evidence IEA] AKAW2_50856S COG:C; EggNog:ENOG410PMCP; InterPro:IPR013149,IPR036291,IPR011032,IPR020843; PFAM:PF00107,PF13602; SMCOG1028:crotonyl-CoA reductase / alcohol dehydrogenase; antiSMASH:Cluster_5.9; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_50857S COG:Q; EggNog:ENOG410Q1C1; InterPro:IPR017871,IPR027417,IPR003593,IPR011527, IPR003439,IPR036640; PFAM:PF00005,PF00664; SMCOG1288:ABC transporter related protein; TransMembrane:13 (o25-46i67-90o96-117i129-146o152-174i305-322o401-422i490- 512o524-543i884-913o933-958i1022-1050o1119-1142i); antiSMASH:Cluster_5.9; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA]; go_function: GO:0042626 - ATPase-coupled transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_50858A COG:S; EggNog:ENOG410PJTY; InterPro:IPR008949,IPR034686; PFAM:PF19086; SMCOG1052:Terpene synthase/cyclase metal-binding domain protein; antiSMASH:Cluster_5.9 AKAW2_50859S COG:S; EggNog:ENOG410PIVU; InterPro:IPR037473,IPR018713; PFAM:PF09995; TransMembrane:2 (i345-364o445-466i); antiSMASH:Cluster_5.9 AKAW2_50860S COG:U; EggNog:ENOG410PN82; InterPro:IPR016635,IPR022775,IPR011012; PFAM:PF01217; antiSMASH:Cluster_5.9; go_process: GO:0015031 - protein transport [Evidence IEA] AKAW2_50861S BUSCO:EOG09263FKC; COG:K; EggNog:ENOG410PK3A; InterPro:IPR038564,IPR015257; PFAM:PF09174; antiSMASH:Cluster_5.9; go_process: GO:0016480 - negative regulation of transcription by RNA polymerase III [Evidence IEA] AKAW2_50862S COG:S; EggNog:ENOG410PHP1 AKAW2_50863A BUSCO:EOG092640BS; COG:U; EggNog:ENOG410PJEE; InterPro:IPR012936,IPR039542; PFAM:PF07970,PF13850 AKAW2_50865S COG:S; EggNog:ENOG410PX8H AKAW2_50864A COG:T; EggNog:ENOG410PG23; InterPro:IPR017441,IPR008271,IPR000719,IPR011009; PFAM:PF07714,PF00069; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_50866S COG:S; EggNog:ENOG410PG6T; InterPro:IPR010482; PFAM:PF06398; TransMembrane:3 (i140-159o236-255i262-279o) AKAW2_50867S COG:Q; EggNog:ENOG410PGIK; InterPro:IPR017871,IPR027417,IPR003593,IPR011527, IPR003439,IPR036640; PFAM:PF00005,PF00664; TransMembrane:17 (o28-49i85-106o112-129i136-155o167-185i264-288o314- 338i440-458o464-484i532-548o554-572i908-929o989-1019i1065- 1083o1089-1108i1173-1194o1200-1220i); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA]; go_function: GO:0042626 - ATPase-coupled transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_50868A SECRETED:SignalP(1-20); TransMembrane:1 (n5-16c20/21o373-392i) AKAW2_50869A COG:J; EggNog:ENOG410PMAH; InterPro:IPR019002; PFAM:PF09420 AKAW2_50870S COG:P; EggNog:ENOG410PJ7D; InterPro:IPR003689; PFAM:PF02535; SECRETED:SignalP(1-29); TransMembrane:6 (n13-24c29/30o74-94i114-134o154-174i309-330o362-385i397- 416o); go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0046873 - metal ion transmembrane transporter activity [Evidence IEA]; go_process: GO:0030001 - metal ion transport [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_50871A CAZy:GT62; COG:G; EggNog:ENOG410PG52; InterPro:IPR029044; PFAM:PF03452; SECRETED:SignalP(1-36) AKAW2_50872A COG:C; EggNog:ENOG410PIF5; InterPro:IPR018108,IPR023395; PFAM:PF00153; TransMembrane:4 (o49-66i157-177o197-214i261-280o) AKAW2_50873A COG:C; EggNog:ENOG410PIF5 AKAW2_50874A COG:S; EggNog:ENOG410PTJP AKAW2_50876A COG:Q; EggNog:ENOG410PVEU; InterPro:IPR002347,IPR036291,IPR020904; PFAM:PF00106,PF13561,PF08659; SMCOG1001:short-chain dehydrogenase/reductase SDR; antiSMASH:Cluster_5.10; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_50877S COG:E; EggNog:ENOG410PMI1; InterPro:IPR002293,IPR004840; PFAM:PF13520,PF00324; SMCOG1038:phenylalanine-specific permease; TransMembrane:12 (i35-62o68-86i122-148o160-179i191-209o229-249i270-295o315- 335i371-389o401-422i443-463o475-493i); antiSMASH:Cluster_5.10; go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0006865 - amino acid transport [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_50878A COG:E; EggNog:ENOG410PI69; InterPro:IPR020855,IPR023696,IPR006035; PFAM:PF00491; SECRETED:SignalP(1-18); antiSMASH:Cluster_5.10; go_function: GO:0016813 - hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines [Evidence IEA]; go_function: GO:0046872 - metal ion binding [Evidence IEA] AKAW2_50879S COG:T; EggNog:ENOG410PNJ2; InterPro:IPR000614,IPR029016,IPR003018; PFAM:PF13185,PF01590; antiSMASH:Cluster_5.10; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_50880A BUSCO:EOG0926384F; COG:G; EggNog:ENOG410PGK0; InterPro:IPR016064,IPR017437,IPR002504; PFAM:PF01513; antiSMASH:Cluster_5.10; go_function: GO:0003951 - NAD+ kinase activity [Evidence IEA]; go_process: GO:0006741 - NADP biosynthetic process [Evidence IEA]; go_process: GO:0019674 - NAD metabolic process [Evidence IEA] AKAW2_50881A COG:J; EggNog:ENOG410PMYB; InterPro:IPR020568,IPR027408,IPR036345; TransMembrane:2 (i90-108o120-146i); antiSMASH:Cluster_5.10 AKAW2_50882S COG:S; EggNog:ENOG410PNU4; InterPro:IPR005645,IPR029058; PFAM:PF03959; antiSMASH:Cluster_5.10 AKAW2_50883A COG:G; EggNog:ENOG410PH0T; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; SMCOG1005:Drug resistance transporter, EmrB/QacA; TransMembrane:14 (i58-84o96-114i126-147o159-176i183-206o212-234i254- 277o289-312i333-353o373-392i399-419o431-452i464-487o530- 548i); antiSMASH:Cluster_5.10; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_50884A COG:E; EggNog:ENOG410Q0GJ; InterPro:IPR005645,IPR029058; PFAM:PF03959; antiSMASH:Cluster_5.10 AKAW2_50885S COG:Q; EggNog:ENOG410PJA1; InterPro:IPR016036,IPR016035,IPR001227,IPR014043, IPR018201,IPR016039,IPR032821,IPR020807,IPR042104, IPR014030,IPR014031,IPR020841; PFAM:PF16197,PF14765,PF00109,PF02801,PF00698; SMCOG1022:Beta-ketoacyl synthase; antiSMASH:Cluster_5.10; go_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein] synthase activity [Evidence IEA]; go_function: GO:0016740 - transferase activity [Evidence IEA]; go_function: GO:0016746 - transferase activity, transferring acyl groups [Evidence IEA]; go_process: GO:0006633 - fatty acid biosynthetic process [Evidence IEA] AKAW2_50886S COG:Q; EggNog:ENOG410Q17C; InterPro:IPR013154,IPR029063,IPR036291,IPR013217, IPR011032,IPR020843; PFAM:PF00107,PF13649,PF13489,PF08240,PF08242, PF08241,PF13602,PF13847; SMCOG1028:crotonyl-CoA reductase / alcohol dehydrogenase; TransMembrane:1 (o783-801i); antiSMASH:Cluster_5.10; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_50887S COG:C; EggNog:ENOG410PIZJ; InterPro:IPR006140,IPR036291,IPR006139,IPR029753, IPR029752; PFAM:PF00389,PF02826; SMCOG1072:dehydrogenase; antiSMASH:Cluster_5.10; go_function: GO:0016616 - oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Evidence IEA]; go_function: GO:0051287 - NAD binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_50888A COG:P,Q; EggNog:ENOG410PFX0; InterPro:IPR017938,IPR017927,IPR013130,IPR013121, IPR039261,IPR013112; PFAM:PF08022,PF01794,PF08030; TransMembrane:6 (o22-45i110-131o143-162i183-204o216-239i251-271o); antiSMASH:Cluster_5.10; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_50889A antiSMASH:Cluster_5.10 AKAW2_50890A COG:K; EggNog:ENOG410QDD9; InterPro:IPR011598,IPR036638,IPR019006; PFAM:PF09427,PF00010; TransMembrane:3 (i362-378o398-415i427-450o); antiSMASH:Cluster_5.10; go_function: GO:0046983 - protein dimerization activity [Evidence IEA]; go_process: GO:0032933 - SREBP signaling pathway [Evidence IEA]; go_process: GO:0045944 - positive regulation of transcription by RNA polymerase II [Evidence IEA] AKAW2_50891A COG:H; EggNog:ENOG410PH96; InterPro:IPR002937,IPR036188; PFAM:PF00070,PF01593,PF13450; antiSMASH:Cluster_5.10; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_50892S COG:Q; EggNog:ENOG410PJR0; InterPro:IPR013154,IPR013149,IPR036291,IPR011032; PFAM:PF00107,PF08240; SMCOG1040:alcohol dehydrogenase; antiSMASH:Cluster_5.10; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_50893S COG:E,O; EggNog:ENOG410PI2P; InterPro:IPR001563,IPR029058; MEROPS:MER0016549; PFAM:PF00450; SECRETED:SignalP(1-18); antiSMASH:Cluster_5.10; go_function: GO:0004185 - serine-type carboxypeptidase activity [Evidence IEA]; go_process: GO:0006508 - proteolysis [Evidence IEA] AKAW2_50894S COG:C; EggNog:ENOG410PKT2; InterPro:IPR006094,IPR036318,IPR016166,IPR012951; PFAM:PF08031,PF01565; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_function: GO:0071949 - FAD binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_50895A COG:S; EggNog:ENOG410PPT2; InterPro:IPR021765; PFAM:PF11807; TransMembrane:1 (i64-86o); go_process: GO:0043386 - mycotoxin biosynthetic process [Evidence IEA] AKAW2_50896S SECRETED:SignalP(1-19) AKAW2_50897A COG:S; EggNog:ENOG410PFBA; InterPro:IPR004104,IPR000683,IPR036291; PFAM:PF02894,PF01408; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA] AKAW2_50898S COG:G; EggNog:ENOG410PJZW; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i57-84o96-117i129-149o155-174i186-205o217-237i286- 309o321-343i350-369o375-398i410-430o442-465i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_50899A CAZy:GH75; COG:G; EggNog:ENOG410PN2D; InterPro:IPR009939; PFAM:PF07335; SECRETED:SignalP(1-20); go_function: GO:0016977 - chitosanase activity [Evidence IEA] AKAW2_50900S COG:G; EggNog:ENOG410PM6H; InterPro:IPR017853,IPR000490; PFAM:PF00332; SECRETED:SignalP(1-22); TransMembrane:1 (n7-17c22/23o428-452i); go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_50902A COG:S; EggNog:ENOG410PWNB AKAW2_50903S COG:S; EggNog:ENOG410PNVZ; InterPro:IPR024983,IPR011990; PFAM:PF12770; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_50904S COG:O; EggNog:ENOG410PU84; InterPro:IPR011118,IPR029058; PFAM:PF07519; SECRETED:SignalP(1-17) AKAW2_50905S COG:S; EggNog:ENOG410PM8I; InterPro:IPR036188,IPR002938; PFAM:PF01494; TransMembrane:2 (o30-48i466-483o); go_function: GO:0071949 - FAD binding [Evidence IEA] AKAW2_50906S CAZy:GH3; COG:G; EggNog:ENOG410PFI5; InterPro:IPR017853,IPR019800,IPR036962,IPR037524, IPR008979,IPR002772,IPR036881,IPR026891,IPR013783, IPR001764,IPR011658; PFAM:PF00933,PF01915,PF14310,PF07691; go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_50907A COG:S; EggNog:ENOG410PWXS; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_50908A COG:E; EggNog:ENOG410PHHD; InterPro:IPR013057; PFAM:PF01490; TransMembrane:11 (i58-77o83-102i132-151o163-182i189-209o229-254i266- 287o307-328i349-368o380-401i413-436o) AKAW2_50909S antiSMASH:Cluster_5.11 AKAW2_50910S antiSMASH:Cluster_5.11 AKAW2_50911A CAZy:GH12; COG:G; EggNog:ENOG410PMUC; InterPro:IPR002594,IPR013319,IPR013320; PFAM:PF01670; SECRETED:SignalP(1-17); antiSMASH:Cluster_5.11; go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_function: GO:0008810 - cellulase activity [Evidence IEA]; go_process: GO:0000272 - polysaccharide catabolic process [Evidence IEA] AKAW2_50912A COG:H; EggNog:ENOG410PHCN; InterPro:IPR000192,IPR015424,IPR015421; PFAM:PF00266; SMCOG1139:aminotransferase class V; antiSMASH:Cluster_5.11; go_function: GO:0003824 - catalytic activity [Evidence IEA] AKAW2_50913S COG:G,M; EggNog:ENOG410PKEI; InterPro:IPR036291,IPR008030; PFAM:PF13460,PF05368; SMCOG1199:NmrA family protein; antiSMASH:Cluster_5.11 AKAW2_50914A COG:S; EggNog:ENOG410PFXI; InterPro:IPR029063,IPR016461,IPR001077; PFAM:PF00891; SMCOG1042:O-methyltransferase; antiSMASH:Cluster_5.11; go_function: GO:0008168 - methyltransferase activity [Evidence IEA]; go_function: GO:0008171 - O-methyltransferase activity [Evidence IEA] AKAW2_50915A antiSMASH:Cluster_5.11 AKAW2_50916A COG:I; EggNog:ENOG410PG86; InterPro:IPR016036,IPR032088,IPR016035,IPR030918, IPR016039,IPR018201,IPR042104,IPR014030,IPR014031, IPR001227,IPR029058,IPR006162,IPR014043,IPR020806, IPR001031,IPR020841,IPR009081,IPR036736; PFAM:PF00550,PF02801,PF00698,PF00975,PF00109, PF16073; SMCOG1022:Beta-ketoacyl synthase; antiSMASH:Cluster_5.11; go_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein] synthase activity [Evidence IEA]; go_function: GO:0016740 - transferase activity [Evidence IEA]; go_function: GO:0016746 - transferase activity, transferring acyl groups [Evidence IEA]; go_function: GO:0016788 - hydrolase activity, acting on ester bonds [Evidence IEA]; go_function: GO:0031177 - phosphopantetheine binding [Evidence IEA]; go_process: GO:0006633 - fatty acid biosynthetic process [Evidence IEA]; go_process: GO:0009058 - biosynthetic process [Evidence IEA] AKAW2_50917A COG:S; EggNog:ENOG410PYE7; InterPro:IPR011008,IPR009799; PFAM:PF07110; antiSMASH:Cluster_5.11; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA] AKAW2_50918A COG:S; EggNog:ENOG410PUMR; InterPro:IPR036188,IPR002938; PFAM:PF01494; SMCOG1087:hypothetical protein; antiSMASH:Cluster_5.11; go_function: GO:0071949 - FAD binding [Evidence IEA] AKAW2_50919S COG:Q; EggNog:ENOG410PWBN; InterPro:IPR001128,IPR017972,IPR002401,IPR036396; PFAM:PF00067; SMCOG1034:cytochrome P450; TransMembrane:1 (o12-34i); antiSMASH:Cluster_5.11; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_50920A COG:S; EggNog:ENOG410PN9K; InterPro:IPR014710,IPR011051,IPR013096; PFAM:PF07883; antiSMASH:Cluster_5.11 AKAW2_50921A COG:S; EggNog:ENOG410PQ98; InterPro:IPR029063,IPR016461,IPR001077; PFAM:PF00891; SMCOG1042:O-methyltransferase; antiSMASH:Cluster_5.11; go_function: GO:0008168 - methyltransferase activity [Evidence IEA]; go_function: GO:0008171 - O-methyltransferase activity [Evidence IEA] AKAW2_50922A COG:S; EggNog:ENOG410PQ98; InterPro:IPR036390,IPR036388; antiSMASH:Cluster_5.11 AKAW2_50923A COG:C; EggNog:ENOG410PMY7; InterPro:IPR001670,IPR018211,IPR039697; PFAM:PF13685,PF00465; antiSMASH:Cluster_5.11; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0046872 - metal ion binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_50924A COG:S; EggNog:ENOG410PJV1; InterPro:IPR036864,IPR001138; PFAM:PF00172; antiSMASH:Cluster_5.11; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_50925A CAZy:GH12; COG:G; EggNog:ENOG410PNCX; InterPro:IPR002594,IPR013319,IPR013320; PFAM:PF01670; SECRETED:SignalP(1-19); antiSMASH:Cluster_5.11; go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_function: GO:0008810 - cellulase activity [Evidence IEA]; go_process: GO:0000272 - polysaccharide catabolic process [Evidence IEA] AKAW2_50926S COG:O; EggNog:ENOG410PH9N; InterPro:IPR036249,IPR040079,IPR036282,IPR004045, IPR016639; PFAM:PF13409,PF13410; antiSMASH:Cluster_5.11; go_function: GO:0004364 - glutathione transferase activity [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0006749 - glutathione metabolic process [Evidence IEA] AKAW2_50927S SECRETED:SignalP(1-18) AKAW2_50928A CAZy:GH135; COG:S; EggNog:ENOG410Q2PQ; InterPro:IPR021986; PFAM:PF12138 AKAW2_50929S COG:F,H; EggNog:ENOG410PJUW; InterPro:IPR038271,IPR001248; PFAM:PF02133; TransMembrane:12 (o39-56i68-87o107-129i193-213o233-252i273-294o323-346i367- 386o392-413i433-453o465-483i495-516o); go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_50930A COG:M; EggNog:ENOG410PKKZ; InterPro:IPR002110,IPR020683,IPR036770; PFAM:PF12796,PF00023,PF13637; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_50931A COG:S; EggNog:ENOG410PR9R; InterPro:IPR043472; antiSMASH:Cluster_5.12 AKAW2_50932A COG:S; EggNog:ENOG410PQ5B; InterPro:IPR000073,IPR029058; PFAM:PF12697; antiSMASH:Cluster_5.12 AKAW2_50933A COG:S; EggNog:ENOG410PS7K; InterPro:IPR014710,IPR011051,IPR013096; PFAM:PF07883; antiSMASH:Cluster_5.12 AKAW2_50934S COG:S; EggNog:ENOG410PY6S; InterPro:IPR000210; antiSMASH:Cluster_5.12; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_50935A COG:S; EggNog:ENOG410PX56; InterPro:IPR021858; antiSMASH:Cluster_5.12 AKAW2_50936A antiSMASH:Cluster_5.12 AKAW2_50937A COG:P; EggNog:ENOG410PV4W; InterPro:IPR018028,IPR011614,IPR024708,IPR002226, IPR020835,IPR024711,IPR037060,IPR010582; PFAM:PF00199,PF06628; antiSMASH:Cluster_5.12; go_function: GO:0004096 - catalase activity [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0006979 - response to oxidative stress [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_50938S CAZy:AA3; COG:E; EggNog:ENOG410PFN0; InterPro:IPR012132,IPR036188,IPR000172,IPR007867; PFAM:PF05199,PF00732; antiSMASH:Cluster_5.12; go_function: GO:0016614 - oxidoreductase activity, acting on CH-OH group of donors [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_50939A COG:Q; EggNog:ENOG410QE5D; InterPro:IPR000873,IPR009081,IPR036291,IPR036736, IPR010080,IPR013120,IPR042099,IPR020845; PFAM:PF00501,PF02719,PF01073,PF16363,PF00550, PF01370,PF07993; SMCOG1010:NAD-dependent epimerase/dehydratase; antiSMASH:Cluster_5.12 AKAW2_50940A antiSMASH:Cluster_5.12 AKAW2_50941S CAZy:GT2_Glyco_tranf_2; COG:M; EggNog:ENOG410Q1IT; InterPro:IPR029044; PFAM:PF13632,PF00535,PF13641; TransMembrane:7 (i27-52o58-74i361-386o398-420i492-514o534-553i593-613o); antiSMASH:Cluster_5.12 AKAW2_50942A COG:U; EggNog:ENOG410QDY7; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; SMCOG1106:major facilitator transporter; TransMembrane:12 (i78-100o112-130i142-160o166-187i199-220o232-251i304- 323o343-365i394-413o419-442i454-477o489-509i); antiSMASH:Cluster_5.12; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_50943S COG:G; EggNog:ENOG410PS5U; InterPro:IPR023271,IPR034294,IPR000425; PFAM:PF00230; TransMembrane:6 (i106-126o146-168i180-200o240-259i266-288o318-337i); antiSMASH:Cluster_5.12; go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0015267 - channel activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_50944A COG:S; EggNog:ENOG410Q2Y5; InterPro:IPR011990,IPR019734; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_50945A COG:S; EggNog:ENOG410Q2ND; InterPro:IPR001077,IPR036388,IPR016461,IPR029063, IPR036390; PFAM:PF00891; go_function: GO:0008168 - methyltransferase activity [Evidence IEA]; go_function: GO:0008171 - O-methyltransferase activity [Evidence IEA] AKAW2_50946S COG:S; EggNog:ENOG410Q1WG; TransMembrane:6 (o20-38i50-71o91-116i128-151o180-202i214-232o) AKAW2_50947A COG:G; EggNog:ENOG410PKKK; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i61-84o104-121i128-145o189-207i219-237o313-331i338- 358o364-386i407-428o434-458i470-489o501-523i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_50948A COG:S; EggNog:ENOG410PPVU; InterPro:IPR036864,IPR021858,IPR001138; PFAM:PF00172; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_50949S COG:T; EggNog:ENOG410PWC7; InterPro:IPR002018,IPR029058; MEROPS:MER0030934; PFAM:PF00135 AKAW2_50950A COG:S; EggNog:ENOG410PIN9; InterPro:IPR006076,IPR036188; PFAM:PF01266; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_50951S COG:S; EggNog:ENOG410PW0Z; InterPro:IPR020915; PFAM:PF11578 AKAW2_50952S COG:I,J,T; EggNog:ENOG410PKS2; InterPro:IPR023631,IPR036928,IPR020556; PFAM:PF01425 AKAW2_50953A COG:G; EggNog:ENOG410PFT2; InterPro:IPR036259; TransMembrane:4 (i20-39o45-68i80-100o112-133i) AKAW2_50954A COG:G; EggNog:ENOG410PFT2; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:6 (i43-61o81-102i109-129o135-158i170-190o202-224i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_50955S COG:K; EggNog:ENOG410Q2XA; InterPro:IPR036864,IPR001138; PFAM:PF00172; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_50956A COG:V; EggNog:ENOG410Q2YE; InterPro:IPR001763,IPR036873; PFAM:PF00581 AKAW2_50957S COG:S; EggNog:ENOG410PGG2; InterPro:IPR016274,IPR000560,IPR029033; PFAM:PF00328; antiSMASH:Cluster_5.13; go_function: GO:0016791 - phosphatase activity [Evidence IEA] AKAW2_50958A COG:G; EggNog:ENOG410PHFT; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; SMCOG1106:major facilitator transporter; TransMembrane:12 (i52-69o92-111i123-143o149-172i184-204o216-239i292- 314o326-345i357-375o381-402i414-431o443-468i); antiSMASH:Cluster_5.13; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_50959A COG:S; EggNog:ENOG410QEEX; InterPro:IPR000073,IPR029058,IPR000639; MEROPS:MER0031611; PFAM:PF12697; SMCOG1262:haloalkane dehalogenase; antiSMASH:Cluster_5.13; go_function: GO:0003824 - catalytic activity [Evidence IEA] AKAW2_50960S COG:T; EggNog:ENOG410PKCM; InterPro:IPR000719,IPR011009,IPR008271; PFAM:PF00069; antiSMASH:Cluster_5.13; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_50961S COG:S; EggNog:ENOG410PKBS; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; TransMembrane:1 (o544-564i); antiSMASH:Cluster_5.13; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_50962A COG:S; EggNog:ENOG410PUCH; InterPro:IPR001077,IPR036388,IPR016461,IPR029063, IPR036390; PFAM:PF00891; SMCOG1042:O-methyltransferase; antiSMASH:Cluster_5.13; go_function: GO:0008168 - methyltransferase activity [Evidence IEA]; go_function: GO:0008171 - O-methyltransferase activity [Evidence IEA] AKAW2_50963A CAZy:AA7; COG:C; EggNog:ENOG410QAHX; InterPro:IPR006094,IPR036318,IPR016169,IPR016166, IPR016167,IPR012951; PFAM:PF08031,PF01565; SMCOG1138:FAD linked oxidase domain protein; antiSMASH:Cluster_5.13; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_function: GO:0071949 - FAD binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_50964S COG:I; EggNog:ENOG410PH4X; InterPro:IPR010071,IPR000873,IPR020845,IPR009081, IPR006162,IPR036291,IPR036736,IPR010080,IPR013120, IPR042099,IPR023213,IPR001242; PFAM:PF00501,PF01370,PF00668,PF00550,PF07993; SMCOG1127:condensation domain-containing protein; TransMembrane:1 (i103-122o); antiSMASH:Cluster_5.13; go_function: GO:0003824 - catalytic activity [Evidence IEA] AKAW2_50965A COG:M; EggNog:ENOG410PF7T; InterPro:IPR035994; antiSMASH:Cluster_5.13; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_process: GO:0009116 - nucleoside metabolic process [Evidence IEA] AKAW2_50966S COG:E; EggNog:ENOG410PNFX; InterPro:IPR029032,IPR003779; PFAM:PF02627; antiSMASH:Cluster_5.13; go_function: GO:0051920 - peroxiredoxin activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_50967A antiSMASH:Cluster_5.13 AKAW2_50968A COG:S; EggNog:ENOG410Q1S1; InterPro:IPR008139; antiSMASH:Cluster_5.13 AKAW2_50969A COG:S; EggNog:ENOG410Q0DU; InterPro:IPR036864,IPR021858,IPR001138; PFAM:PF00172; antiSMASH:Cluster_5.13; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_50970S COG:S; EggNog:ENOG410PU7C; InterPro:IPR007568; PFAM:PF04479; TransMembrane:5 (o37-59i71-91o111-134i164-182o197-217i); antiSMASH:Cluster_5.13; go_component: GO:0016021 - integral component of membrane [Evidence IEA] AKAW2_50971A COG:S; EggNog:ENOG410PUVA; InterPro:IPR029063; PFAM:PF13489,PF13847,PF13649 AKAW2_50972S COG:S; EggNog:ENOG410Q1DT; InterPro:IPR018809; PFAM:PF10295 AKAW2_50973S CAZy:CBM43; CAZy:GH72; COG:S; EggNog:ENOG410PFK7; InterPro:IPR012946,IPR017853,IPR004886; PFAM:PF07983,PF03198; TransMembrane:1 (n3-13c21/22o421-441i) AKAW2_50974A COG:S; EggNog:ENOG410PY1Y; InterPro:IPR036568,IPR009288; PFAM:PF06094 AKAW2_50976A CAZy:AA7; COG:S; EggNog:ENOG410QEF8; InterPro:IPR006094,IPR036318,IPR016166,IPR012951; PFAM:PF08031,PF01565; SECRETED:SignalP(1-19); go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_function: GO:0071949 - FAD binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_50977S COG:S; EggNog:ENOG410PP1S; TransMembrane:7 (o16-40i52-75o95-118i130-153o173-197i209-232o252-276i) AKAW2_50978A COG:S; EggNog:ENOG410Q2V2; InterPro:IPR029058; SECRETED:SignalP(1-23) AKAW2_50979S CAZy:CE8; COG:G; EggNog:ENOG410PJNK; InterPro:IPR012334,IPR018040,IPR000070,IPR033131, IPR011050; PFAM:PF01095; TransMembrane:1 (i31-52o); antiSMASH:Cluster_5.14; go_function: GO:0030599 - pectinesterase activity [Evidence IEA]; go_process: GO:0042545 - cell wall modification [Evidence IEA] AKAW2_50980A COG:Q; EggNog:ENOG410PU9T; InterPro:IPR011234,IPR036663; PFAM:PF01557; antiSMASH:Cluster_5.14; go_function: GO:0003824 - catalytic activity [Evidence IEA] AKAW2_50981A COG:S; EggNog:ENOG410PKJ6; InterPro:IPR004360,IPR037523,IPR029068; PFAM:PF00903; antiSMASH:Cluster_5.14 AKAW2_50982S COG:S; EggNog:ENOG410PTEQ; antiSMASH:Cluster_5.14 AKAW2_50983A COG:S; EggNog:ENOG410Q1IN; InterPro:IPR014756,IPR011021,IPR014752; PFAM:PF00339; antiSMASH:Cluster_5.14 AKAW2_50984S CAZy:GT2_Chitin_synth; COG:M; EggNog:ENOG410Q1ZC; InterPro:IPR029044,IPR004835,IPR004834,IPR013616; PFAM:PF01644,PF08407,PF13632; TransMembrane:7 (o502-518i530-556o586-607i619-644o664-691i798-815o835- 860i); antiSMASH:Cluster_5.14; go_function: GO:0004100 - chitin synthase activity [Evidence IEA]; go_function: GO:0016758 - transferase activity, transferring hexosyl groups [Evidence IEA]; go_process: GO:0006031 - chitin biosynthetic process [Evidence IEA] AKAW2_50985S COG:S; EggNog:ENOG410PV6M; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172; antiSMASH:Cluster_5.14; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_50986S COG:Q; EggNog:ENOG410QD7U; InterPro:IPR016036,IPR016035,IPR016039,IPR042104, IPR014030,IPR011032,IPR013968,IPR001227,IPR032821, IPR014031,IPR014043,IPR020807,IPR020843,IPR020841, IPR029063,IPR036291,IPR013217; PFAM:PF16197,PF00109,PF08659,PF13489,PF02801, PF00698,PF13649,PF13602,PF14765,PF00107,PF00106,PF08242, PF08241; SMCOG1022:Beta-ketoacyl synthase; antiSMASH:Cluster_5.14; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0016740 - transferase activity [Evidence IEA]; go_function: GO:0016746 - transferase activity, transferring acyl groups [Evidence IEA] AKAW2_50987A COG:C,H; EggNog:ENOG410PVYZ; InterPro:IPR036188,IPR002938; PFAM:PF01494; SMCOG1050:monooxygenase FAD-binding; antiSMASH:Cluster_5.14; go_function: GO:0071949 - FAD binding [Evidence IEA] AKAW2_50988S COG:S; EggNog:ENOG410PRMF; InterPro:IPR036236,IPR007219,IPR013087; PFAM:PF13894,PF04082,PF00096; antiSMASH:Cluster_5.14; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA] AKAW2_50989S COG:S; EggNog:ENOG410PRMF; antiSMASH:Cluster_5.14 AKAW2_50990S COG:I; EggNog:ENOG410Q1EU; InterPro:IPR006694; PFAM:PF04116; TransMembrane:3 (o61-80i100-120o140-158i); antiSMASH:Cluster_5.14; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0008610 - lipid biosynthetic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_50991S COG:S; EggNog:ENOG410PSE9; InterPro:IPR000182,IPR016181; PFAM:PF00583; antiSMASH:Cluster_5.14; go_function: GO:0008080 - N-acetyltransferase activity [Evidence IEA] AKAW2_50992A antiSMASH:Cluster_5.14 AKAW2_50993S COG:Q; EggNog:ENOG410PJ3Q; InterPro:IPR013154,IPR013149,IPR002328,IPR036291, IPR011032,IPR020843; PFAM:PF00107,PF08240; SMCOG1040:alcohol dehydrogenase; antiSMASH:Cluster_5.14; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_50994A COG:S; EggNog:ENOG410PTRC; InterPro:IPR031818,IPR038744; PFAM:PF16815; antiSMASH:Cluster_5.14 AKAW2_50995A COG:S; EggNog:ENOG410PRGU; InterPro:IPR020915; PFAM:PF11578; SECRETED:SignalP(1-29); antiSMASH:Cluster_5.14 AKAW2_50996A COG:Q; EggNog:ENOG410PK6Z; InterPro:IPR001128,IPR002401,IPR036396; PFAM:PF00067; SECRETED:SignalP(1-21); SMCOG1034:cytochrome P450; antiSMASH:Cluster_5.14; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_50997A COG:S; EggNog:ENOG410PT0H; InterPro:IPR000210,IPR011333; PFAM:PF00651; antiSMASH:Cluster_5.14; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_50998A COG:S; EggNog:ENOG410PKES; InterPro:IPR001279,IPR036866; PFAM:PF00753; antiSMASH:Cluster_5.14 AKAW2_50999S COG:Q; EggNog:ENOG410PIDT; InterPro:IPR020946,IPR036188; PFAM:PF13450; go_function: GO:0004499 - N,N-dimethylaniline monooxygenase activity [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_function: GO:0050661 - NADP binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_51000A CAZy:CE10; COG:V; EggNog:ENOG410PH6G; InterPro:IPR029058,IPR013094; MEROPS:MER0034961; PFAM:PF07859; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_51001S COG:C; EggNog:ENOG410PWXW; InterPro:IPR036188,IPR002938; PFAM:PF01494; go_function: GO:0071949 - FAD binding [Evidence IEA] AKAW2_51002S COG:S; EggNog:ENOG410PX5I; InterPro:IPR036864,IPR021858,IPR001138; PFAM:PF00172,PF11951; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_51004A COG:S; EggNog:ENOG410PQCP AKAW2_51005A COG:G; EggNog:ENOG410PJQX; InterPro:IPR011701,IPR036259; PFAM:PF07690; TransMembrane:5 (n4-15c19/20o29-48i190-208o220-241i253-272o278-300i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_51006A COG:G; EggNog:ENOG410PJQX; InterPro:IPR020846,IPR011701,IPR036259; TransMembrane:1 (i55-72o); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_51007A COG:G; EggNog:ENOG410PMGT; InterPro:IPR012083,IPR017850,IPR000917,IPR024607; PFAM:PF00884; SECRETED:SignalP(1-16); go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0004065 - arylsulfatase activity [Evidence IEA]; go_function: GO:0008484 - sulfuric ester hydrolase activity [Evidence IEA]; go_process: GO:0018958 - phenol-containing compound metabolic process [Evidence IEA] AKAW2_51008A CAZy:CBM20; CAZy:GH15; COG:G; EggNog:ENOG410PJ6P; InterPro:IPR034836,IPR008291,IPR013783,IPR011613, IPR000165,IPR008928,IPR013784,IPR012341,IPR002044; PFAM:PF00686,PF00723; SECRETED:SignalP(1-18); go_function: GO:0004339 - glucan 1,4-alpha-glucosidase activity [Evidence IEA]; go_function: GO:0030246 - carbohydrate binding [Evidence IEA]; go_function: GO:2001070 - starch binding [Evidence IEA]; go_process: GO:0000272 - polysaccharide catabolic process [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA]; go_process: GO:0005976 - polysaccharide metabolic process [Evidence IEA] AKAW2_51009A COG:T; EggNog:ENOG410PJPI; InterPro:IPR019826,IPR002018,IPR029058; MEROPS:MER0033198; PFAM:PF00135; SECRETED:SignalP(1-18) AKAW2_51010A COG:E; EggNog:ENOG410PNRU; InterPro:IPR036551,IPR003382,IPR004507; PFAM:PF02441; TransMembrane:1 (i43-63o); go_function: GO:0003824 - catalytic activity [Evidence IEA] AKAW2_51011A COG:K; EggNog:ENOG410PIEG; InterPro:IPR036864,IPR007219,IPR004507,IPR001138; PFAM:PF00172; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_51012A COG:H; EggNog:ENOG410PKET; InterPro:IPR032903,IPR002830; PFAM:PF01977; go_function: GO:0016831 - carboxy-lyase activity [Evidence IEA] AKAW2_51013S COG:T; EggNog:ENOG410PXX8; InterPro:IPR000210,IPR011333; PFAM:PF00651; TransMembrane:1 (i12-29o); go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_51015S COG:C; EggNog:ENOG410PKE4; InterPro:IPR012349,IPR002563; PFAM:PF01613; go_function: GO:0010181 - FMN binding [Evidence IEA] AKAW2_51016A COG:I; EggNog:ENOG410PMHS; InterPro:IPR002018,IPR029058; MEROPS:MER0078701; PFAM:PF00135 AKAW2_51017A COG:S; EggNog:ENOG410Q22F AKAW2_51018S COG:S; EggNog:ENOG410PIPE; InterPro:IPR017946; SECRETED:SignalP(1-21); TransMembrane:1 (n3-14c21/22o445-463i); go_function: GO:0008081 - phosphoric diester hydrolase activity [Evidence IEA]; go_process: GO:0006629 - lipid metabolic process [Evidence IEA] AKAW2_51019S COG:E; EggNog:ENOG410PFC6; InterPro:IPR000109,IPR018456,IPR036259; PFAM:PF00854; TransMembrane:11 (o150-169i181-201o207-226i265-287o293-314i394-412o432- 452i464-486o511-535i547-569o575-595i); go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0006857 - oligopeptide transport [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_51020A COG:S; EggNog:ENOG410PJJM; InterPro:IPR027417,IPR011990; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_51021A COG:I; EggNog:ENOG410PUXY; InterPro:IPR036188,IPR002938; PFAM:PF01494; TransMembrane:1 (o18-36i); go_function: GO:0071949 - FAD binding [Evidence IEA] AKAW2_51022A COG:Q; EggNog:ENOG410PHTP; InterPro:IPR020946,IPR036188; PFAM:PF07992,PF13738,PF13450; go_function: GO:0004499 - N,N-dimethylaniline monooxygenase activity [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_function: GO:0050661 - NADP binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_51023S CAZy:CE10; COG:I; EggNog:ENOG410PR6J; InterPro:IPR029058,IPR013094; MEROPS:MER0034960; PFAM:PF10340,PF07859; TransMembrane:1 (i109-129o); go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_51024A COG:Q; EggNog:ENOG410PPUC; InterPro:IPR002347,IPR036291,IPR020904; PFAM:PF00106,PF13561,PF08659; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_51025S COG:Q; EggNog:ENOG410PMR7; InterPro:IPR001128,IPR002403,IPR036396; PFAM:PF00067; TransMembrane:1 (n4-9c14/15o30-53i); go_function: GO:0004497 - monooxygenase activity [Evidence IEA]; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_51026A COG:H; EggNog:ENOG410PIGQ; InterPro:IPR027417,IPR011629,IPR003495; PFAM:PF02492,PF07683 AKAW2_51027A CAZy:GH28; COG:G; EggNog:ENOG410PH3U; InterPro:IPR000743,IPR012334,IPR011050; PFAM:PF00295; SECRETED:SignalP(1-15); go_function: GO:0004650 - polygalacturonase activity [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_51028A COG:S; EggNog:ENOG410PR9G; InterPro:IPR023352,IPR001129; PFAM:PF01124; TransMembrane:5 (i25-42o54-71i116-136o148-165i177-194o) AKAW2_51029A COG:S; EggNog:ENOG410PR9G; InterPro:IPR007219; PFAM:PF04082; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA] AKAW2_51030S COG:S; EggNog:ENOG410PY6Q; InterPro:IPR032805; PFAM:PF13813; TransMembrane:5 (i26-42o48-70i312-331o337-357i378-394o) AKAW2_51031A InterPro:IPR032675 AKAW2_51032S COG:S; EggNog:ENOG410PSY2 AKAW2_51033A COG:S; EggNog:ENOG410PWSJ; InterPro:IPR018535; PFAM:PF09362; SECRETED:SignalP(1-20) AKAW2_51035A COG:E; EggNog:ENOG410PKBA; InterPro:IPR001381,IPR006151,IPR027417,IPR036291, IPR013708,IPR013785,IPR031322; PFAM:PF01202,PF08501,PF01487; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0003855 - 3-dehydroquinate dehydratase activity [Evidence IEA]; go_function: GO:0004764 - shikimate 3-dehydrogenase (NADP+) activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_51036S COG:K; EggNog:ENOG410PMIY; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_51037A COG:S; EggNog:ENOG410PJF1; InterPro:IPR013860; PFAM:PF08550 AKAW2_51038S BUSCO:EOG092652NQ; COG:J; EggNog:ENOG410PNU3; InterPro:IPR001950,IPR036877; PFAM:PF01253; go_function: GO:0003743 - translation initiation factor activity [Evidence IEA]; go_process: GO:0006413 - translational initiation [Evidence IEA] AKAW2_51039A COG:S; EggNog:ENOG410PPC7; TransMembrane:1 (i335-356o) AKAW2_51040A COG:J; EggNog:ENOG410PQQG; InterPro:IPR005579; PFAM:PF03879 AKAW2_51041S COG:C; EggNog:ENOG410PKNC; InterPro:IPR018108,IPR023395; PFAM:PF00153 AKAW2_51042S BUSCO:EOG09264RJL; COG:F; EggNog:ENOG410PPBI; InterPro:IPR006262,IPR002125,IPR016193; PFAM:PF00383,PF08211; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0004126 - cytidine deaminase activity [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0009972 - cytidine deamination [Evidence IEA] AKAW2_51043A COG:U; EggNog:ENOG410PFJT; InterPro:IPR031777,IPR031778,IPR015943,IPR006581; PFAM:PF15899,PF15901,PF15902; SECRETED:SignalP(1-23); TransMembrane:2 (n6-17c23/24o1351-1372i1400-1423o); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_51044A COG:S; EggNog:ENOG410PG08 AKAW2_51045A BUSCO:EOG09260WUS; COG:U; EggNog:ENOG410PH9F; InterPro:IPR009976,IPR033960; PFAM:PF07393; TransMembrane:1 (o642-664i); go_component: GO:0000145 - exocyst [Evidence IEA]; go_component: GO:0005737 - cytoplasm [Evidence IEA]; go_process: GO:0006887 - exocytosis [Evidence IEA] AKAW2_51046S BUSCO:EOG09264W7W; COG:I; EggNog:ENOG410PGDW; InterPro:IPR038887,IPR036424; TransMembrane:1 (i67-85o); go_component: GO:1904423 - dehydrodolichyl diphosphate synthase complex [Evidence IEA]; go_function: GO:0016765 - transferase activity, transferring alkyl or aryl (other than methyl) groups [Evidence IEA]; go_process: GO:0019408 - dolichol biosynthetic process [Evidence IEA] AKAW2_51047A COG:S; EggNog:ENOG410PSNB AKAW2_51048S COG:T; EggNog:ENOG410PFWZ; InterPro:IPR016024,IPR011989,IPR011993,IPR001849, IPR006816,IPR024574; PFAM:PF11841,PF04727,PF16457 AKAW2_51049S BUSCO:EOG09263HK2; COG:L; EggNog:ENOG410PFQ2; InterPro:IPR027417,IPR004582; PFAM:PF03215; go_process: GO:0006281 - DNA repair [Evidence IEA] AKAW2_51051S COG:G; EggNog:ENOG410PIRD; InterPro:IPR013657; TransMembrane:5 (n17-28c33/34o49-68i88-107o180-203i215-237o243-261i); go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_51050A COG:U; EggNog:ENOG410PF9U; InterPro:IPR030381,IPR027417,IPR003130,IPR001401, IPR000375,IPR022812,IPR020850; PFAM:PF01031,PF02212; go_function: GO:0003924 - GTPase activity [Evidence IEA]; go_function: GO:0005525 - GTP binding [Evidence IEA] AKAW2_51052A COG:Z; EggNog:ENOG410PJW6; InterPro:IPR002108,IPR036028,IPR035718,IPR035719, IPR001452,IPR029006; PFAM:PF14604,PF00241,PF07653,PF00018; go_function: GO:0003779 - actin binding [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_51053S BUSCO:EOG09260BYL; COG:F; EggNog:ENOG410PGKE; InterPro:IPR006329,IPR001365,IPR032466,IPR006650; PFAM:PF00962; TransMembrane:1 (o641-658i); go_function: GO:0003876 - AMP deaminase activity [Evidence IEA]; go_function: GO:0019239 - deaminase activity [Evidence IEA]; go_process: GO:0009168 - purine ribonucleoside monophosphate biosynthetic process [Evidence IEA]; go_process: GO:0032264 - IMP salvage [Evidence IEA] AKAW2_51054A COG:S; EggNog:ENOG410PNZE AKAW2_51055S COG:S; EggNog:ENOG410PRAU AKAW2_51056A BUSCO:EOG09260EPS; COG:U,Y; EggNog:ENOG410PM1I; InterPro:IPR037624,IPR014908,IPR007187; PFAM:PF08801,PF03177; go_function: GO:0017056 - structural constituent of nuclear pore [Evidence IEA] AKAW2_51057S COG:I; EggNog:ENOG410PJ58; InterPro:IPR001227,IPR016036,IPR014043,IPR016035; go_function: GO:0016740 - transferase activity [Evidence IEA] AKAW2_51058A COG:U; EggNog:ENOG410PQJE; InterPro:IPR011012,IPR006722; PFAM:PF04628; go_process: GO:0006888 - endoplasmic reticulum to Golgi vesicle-mediated transport [Evidence IEA] AKAW2_51059S COG:C; EggNog:ENOG410PGDV; InterPro:IPR006138,IPR006137; PFAM:PF01058; go_function: GO:0008137 - NADH dehydrogenase (ubiquinone) activity [Evidence IEA]; go_function: GO:0048038 - quinone binding [Evidence IEA]; go_function: GO:0051536 - iron-sulfur cluster binding [Evidence IEA]; go_function: GO:0051539 - 4 iron, 4 sulfur cluster binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_51060S BUSCO:EOG09263ROQ; COG:A; EggNog:ENOG410PIGW; InterPro:IPR012173; PFAM:PF04006; go_component: GO:0005634 - nucleus [Evidence IEA]; go_component: GO:0005732 - small nucleolar ribonucleoprotein complex [Evidence IEA]; go_component: GO:0034457 - Mpp10 complex [Evidence IEA]; go_process: GO:0006364 - rRNA processing [Evidence IEA] AKAW2_51061A COG:A; EggNog:ENOG410QE65; InterPro:IPR033684,IPR029063,IPR019410; PFAM:PF10294 AKAW2_51062S COG:S; EggNog:ENOG410PP5N; InterPro:IPR013879; PFAM:PF08570; TransMembrane:4 (o14-35i56-81o93-114i126-144o) AKAW2_51063A COG:S; EggNog:ENOG410PP64; InterPro:IPR016813 AKAW2_51064A BUSCO:EOG0926578E; COG:O; EggNog:ENOG410PRGF; InterPro:IPR036249,IPR013766,IPR000866; PFAM:PF00578,PF08534; go_function: GO:0016209 - antioxidant activity [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_51065S BUSCO:EOG092641K1; COG:U; EggNog:ENOG410PIR9; InterPro:IPR006797,IPR037365; PFAM:PF04707; go_component: GO:0005758 - mitochondrial intermembrane space [Evidence IEA] AKAW2_51066S COG:I; EggNog:ENOG410PGX0; InterPro:IPR041723,IPR004821,IPR014729; PFAM:PF01467; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_process: GO:0009058 - biosynthetic process [Evidence IEA] AKAW2_51067A COG:O; EggNog:ENOG410PNPZ; InterPro:IPR004480,IPR036249,IPR002109,IPR033658; PFAM:PF00462; go_function: GO:0015035 - protein disulfide oxidoreductase activity [Evidence IEA] AKAW2_51068S COG:H; EggNog:ENOG410PGN4; InterPro:IPR036551,IPR003382; PFAM:PF02441; go_function: GO:0003824 - catalytic activity [Evidence IEA] AKAW2_51069A COG:H; EggNog:ENOG410PFPH; InterPro:IPR039653,IPR000537; PFAM:PF01040; TransMembrane:5 (i42-65o85-108i129-148o154-172i184-203o); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0016765 - transferase activity, transferring alkyl or aryl (other than methyl) groups [Evidence IEA] AKAW2_51070S COG:S; EggNog:ENOG410PJN0; InterPro:IPR018866,IPR003347; PFAM:PF10497,PF02373 AKAW2_51071A COG:S; EggNog:ENOG410PQAC; TransMembrane:4 (i49-73o79-99i120-139o151-169i) AKAW2_51072S BUSCO:EOG09265LIB; COG:S; EggNog:ENOG410PNZD; InterPro:IPR014807,IPR042432; PFAM:PF08695; TransMembrane:1 (i62-79o); go_process: GO:0033617 - mitochondrial cytochrome c oxidase assembly [Evidence IEA] AKAW2_51073A BUSCO:EOG092642CB; COG:J; EggNog:ENOG410PJBS; InterPro:IPR000597,IPR009000,IPR019927,IPR019926; go_component: GO:0005840 - ribosome [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_process: GO:0006412 - translation [Evidence IEA] AKAW2_51075S BUSCO:EOG09265B4G; COG:S; EggNog:ENOG410PNX1; InterPro:IPR009688; PFAM:PF06916; TransMembrane:1 (i108-131o) AKAW2_51074A COG:P; EggNog:ENOG410PG41; InterPro:IPR002110,IPR030395,IPR017946,IPR036770, IPR020683,IPR004331; PFAM:PF12796,PF00023,PF03009,PF13637; go_function: GO:0005515 - protein binding [Evidence IEA]; go_function: GO:0008081 - phosphoric diester hydrolase activity [Evidence IEA]; go_process: GO:0006629 - lipid metabolic process [Evidence IEA] AKAW2_51076A COG:S; EggNog:ENOG410PPZR; TransMembrane:1 (n4-15c20/21o189-211i) AKAW2_51077A COG:S; EggNog:ENOG410PMAD; TransMembrane:1 (o78-98i) AKAW2_51078A COG:S; EggNog:ENOG410PPFS AKAW2_51080S COG:F,P; EggNog:ENOG410PG6B; InterPro:IPR005829,IPR005828,IPR003663,IPR036259, IPR020846; PFAM:PF00083,PF07690; TransMembrane:12 (i47-65o93-114i121-144o150-167i179-201o207-229i327- 346o352-372i379-400o420-439i459-480o492-510i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_51081S COG:S; EggNog:ENOG410PTWB AKAW2_51082A COG:U; EggNog:ENOG410PGDS; InterPro:IPR036322,IPR015943,IPR001680,IPR037363, IPR020472,IPR037596,IPR017986; PFAM:PF00400; go_component: GO:0030127 - COPII vesicle coat [Evidence IEA]; go_function: GO:0005198 - structural molecule activity [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0016192 - vesicle-mediated transport [Evidence IEA]; go_process: GO:0090114 - COPII-coated vesicle budding [Evidence IEA]; go_process: GO:1904263 - positive regulation of TORC1 signaling [Evidence IEA] AKAW2_51083S COG:S; EggNog:ENOG410PQX7; InterPro:IPR024111 AKAW2_51084S COG:S; EggNog:ENOG410Q2UE AKAW2_51085A COG:B,K; EggNog:ENOG410PISS; InterPro:IPR006939; PFAM:PF04855; go_component: GO:0000228 - nuclear chromosome [Evidence IEA]; go_process: GO:0006338 - chromatin remodeling [Evidence IEA] AKAW2_51086A COG:S; EggNog:ENOG410PNDS; InterPro:IPR011333 AKAW2_51087A COG:S; EggNog:ENOG410PG5W; InterPro:IPR005317,IPR039461; MEROPS:MER0004247; PFAM:PF03571; go_component: GO:0005737 - cytoplasm [Evidence IEA]; go_function: GO:0008239 - dipeptidyl-peptidase activity [Evidence IEA]; go_function: GO:0070006 - metalloaminopeptidase activity [Evidence IEA]; go_process: GO:0006508 - proteolysis [Evidence IEA] AKAW2_51088A BUSCO:EOG09261YGB; COG:T; EggNog:ENOG410PH91; InterPro:IPR016024,IPR011989,IPR000719,IPR011009; PFAM:PF07714,PF00069; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_51089S COG:E; EggNog:ENOG410PIW1; InterPro:IPR036038,IPR018300,IPR001544,IPR043131, IPR043132,IPR033939,IPR005786; PFAM:PF01063; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0004084 - branched-chain-amino-acid transaminase activity [Evidence IEA]; go_process: GO:0009081 - branched-chain amino acid metabolic process [Evidence IEA] AKAW2_51090S COG:S; EggNog:ENOG410PRE1; InterPro:IPR004827; go_function: GO:0003700 - DNA-binding transcription factor activity [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_51091A COG:D,K,T; EggNog:ENOG410PIHQ; InterPro:IPR000704,IPR016149,IPR035991; PFAM:PF01214; go_component: GO:0005956 - protein kinase CK2 complex [Evidence IEA]; go_function: GO:0019887 - protein kinase regulator activity [Evidence IEA] AKAW2_51092A COG:K; EggNog:ENOG410PKDD; InterPro:IPR007219; TransMembrane:1 (o469-487i); go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA] AKAW2_51093S COG:B,T; EggNog:ENOG410PPT5; InterPro:IPR041667,IPR003347; PFAM:PF13621 AKAW2_51094S COG:S; EggNog:ENOG410PTSW; SECRETED:SignalP(1-28) AKAW2_51095A COG:E; EggNog:ENOG410QDKR; InterPro:IPR004840,IPR004841; PFAM:PF13520,PF00324; TransMembrane:12 (i67-84o96-123i144-169o175-197i209-229o256-276i297- 318o350-373i394-416o428-448i474-496o502-522i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_process: GO:0006865 - amino acid transport [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_51096S COG:S; EggNog:ENOG410PQG9; InterPro:IPR036400,IPR001199; PFAM:PF00173 AKAW2_51097A BUSCO:EOG09260XQV; COG:A; EggNog:ENOG410PI4R; InterPro:IPR012677,IPR000504,IPR003954,IPR035979; PFAM:PF00076; go_function: GO:0003676 - nucleic acid binding [Evidence IEA] AKAW2_51098S BUSCO:EOG09264DOU; COG:L; EggNog:ENOG410PP98; InterPro:IPR004579,IPR010994,IPR011335; PFAM:PF03834; go_component: GO:0005634 - nucleus [Evidence IEA]; go_function: GO:0003684 - damaged DNA binding [Evidence IEA]; go_process: GO:0006281 - DNA repair [Evidence IEA] AKAW2_51099S COG:S; EggNog:ENOG410PVX5; InterPro:IPR021858 AKAW2_51100A COG:U; EggNog:ENOG410PFRA; InterPro:IPR013599,IPR016439,IPR006634; PFAM:PF08390,PF03798; TransMembrane:8 (i41-62o92-114i135-157o177-195i207-227o233-250i257- 277o337-358i); go_component: GO:0016021 - integral component of membrane [Evidence IEA] AKAW2_51101A BUSCO:EOG092608ZS; COG:I; EggNog:ENOG410PH8V; InterPro:IPR023282,IPR002202,IPR023076,IPR023074, IPR025583,IPR000731,IPR009023,IPR004554,IPR009029; PFAM:PF00368,PF13323,PF12349; TransMembrane:7 (o228-249i256-276o282-302i345-364o370-392i446-465o1034- 1056i); go_function: GO:0004420 - hydroxymethylglutaryl-CoA reductase (NADPH) activity [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_function: GO:0016616 - oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Evidence IEA]; go_process: GO:0008299 - isoprenoid biosynthetic process [Evidence IEA]; go_process: GO:0015936 - coenzyme A metabolic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_51102A COG:S; EggNog:ENOG410PP62; TransMembrane:5 (o6-27i53-71o160-178i190-208o228-253i) AKAW2_51103A COG:S; EggNog:ENOG410PPU0; TransMembrane:4 (o20-40i47-69o89-110i122-148o) AKAW2_51104S COG:Z; EggNog:ENOG410PVCJ; InterPro:IPR011990,IPR027417,IPR007111,IPR029058; PFAM:PF13374,PF05729,PF13424; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_51106A COG:S; EggNog:ENOG410PNAC AKAW2_51107S COG:U; EggNog:ENOG410PQMB; InterPro:IPR029012,IPR028945,IPR027538; PFAM:PF04420; TransMembrane:1 (o6-34i); go_component: GO:0043529 - GET complex [Evidence IEA]; go_process: GO:0071816 - tail-anchored membrane protein insertion into ER membrane [Evidence IEA] AKAW2_51108A BUSCO:EOG09264T8I; COG:A; EggNog:ENOG410PMWF; InterPro:IPR000504,IPR012677,IPR035979; PFAM:PF00076; go_function: GO:0003676 - nucleic acid binding [Evidence IEA] AKAW2_51109S COG:A; EggNog:ENOG410PSF0; InterPro:IPR040424,IPR010304; go_component: GO:0005634 - nucleus [Evidence IEA]; go_component: GO:0005737 - cytoplasm [Evidence IEA]; go_function: GO:0003723 - RNA binding [Evidence IEA]; go_process: GO:0006397 - mRNA processing [Evidence IEA] AKAW2_51110A SECRETED:SignalP(1-21) AKAW2_51111A COG:S; EggNog:ENOG410PREH AKAW2_51113A COG:S; EggNog:ENOG410PREH; SECRETED:SignalP(1-28) AKAW2_51112S COG:S; EggNog:ENOG410PMYE; SECRETED:SignalP(1-19) AKAW2_51114A COG:I; EggNog:ENOG410PHV6; InterPro:IPR016039,IPR020613,IPR020617,IPR020616, IPR020615; PFAM:PF00108,PF02803; go_function: GO:0016746 - transferase activity, transferring acyl groups [Evidence IEA]; go_function: GO:0016747 - transferase activity, transferring acyl groups other than amino-acyl groups [Evidence IEA] AKAW2_51115S COG:C; EggNog:ENOG410PISP; InterPro:IPR018108,IPR023395,IPR002067; PFAM:PF00153; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_51116S COG:S; EggNog:ENOG410PGMC; InterPro:IPR038499,IPR025304,IPR004328; PFAM:PF13949,PF03097; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_51117A InterPro:IPR022085; PFAM:PF12311 AKAW2_51118A COG:S; EggNog:ENOG410PKQA; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_51119A COG:E; EggNog:ENOG410PKTF; InterPro:IPR001381,IPR013785; PFAM:PF01487; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0003855 - 3-dehydroquinate dehydratase activity [Evidence IEA] AKAW2_51121A COG:T; EggNog:ENOG410PH23; InterPro:IPR001194,IPR005113,IPR005112,IPR037516, IPR043153,IPR002219; PFAM:PF03456,PF03455,PF02141; TransMembrane:2 (o520-540i561-579o); go_process: GO:0035556 - intracellular signal transduction [Evidence IEA] AKAW2_51122A COG:S; EggNog:ENOG410PNI2; InterPro:IPR010378; PFAM:PF06159 AKAW2_51123S COG:O; EggNog:ENOG410PNR8; InterPro:IPR001841,IPR039903,IPR007527,IPR013083; PFAM:PF13639,PF12861; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_function: GO:0061630 - ubiquitin protein ligase activity [Evidence IEA] AKAW2_51124A COG:S; EggNog:ENOG410PGEK; InterPro:IPR007902; PFAM:PF05238; go_process: GO:0007059 - chromosome segregation [Evidence IEA]; go_process: GO:0051382 - kinetochore assembly [Evidence IEA] AKAW2_51125S COG:K; EggNog:ENOG410PQZ4; InterPro:IPR004827; PFAM:PF07716; go_function: GO:0003700 - DNA-binding transcription factor activity [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_51126A COG:S; EggNog:ENOG410PNYT AKAW2_51127A TransMembrane:1 (i12-37o) AKAW2_51128S COG:L; EggNog:ENOG410PHBW; InterPro:IPR014790,IPR036890,IPR028830,IPR038973, IPR037198; PFAM:PF13589,PF08676; go_component: GO:0032300 - mismatch repair complex [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA]; go_process: GO:0006298 - mismatch repair [Evidence IEA] AKAW2_51129A COG:T; EggNog:ENOG410QDPW; InterPro:IPR000651,IPR036964,IPR023578,IPR036028, IPR008937,IPR001895,IPR001452; PFAM:PF00617,PF00618; go_function: GO:0005085 - guanyl-nucleotide exchange factor activity [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0007264 - small GTPase mediated signal transduction [Evidence IEA] AKAW2_51131A COG:S; EggNog:ENOG410Q0BW; InterPro:IPR002110,IPR027417,IPR007111,IPR036770, IPR020683,IPR031359; PFAM:PF05729,PF17100; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_51132A COG:K; EggNog:ENOG410PKED; InterPro:IPR014801; PFAM:PF08689; TransMembrane:1 (i356-377o); go_component: GO:0016592 - mediator complex [Evidence IEA]; go_function: GO:0003712 - transcription coregulator activity [Evidence IEA]; go_process: GO:0006357 - regulation of transcription by RNA polymerase II [Evidence IEA] AKAW2_51133S COG:S; EggNog:ENOG410PP4W AKAW2_51134S COG:E; EggNog:ENOG410PGWM; InterPro:IPR006095,IPR006097,IPR006096,IPR036291, IPR033922,IPR014362,IPR033524; PFAM:PF00208,PF02812; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0016639 - oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [Evidence IEA]; go_process: GO:0006520 - cellular amino acid metabolic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_51135A COG:G; EggNog:ENOG410PGBC; InterPro:IPR011701,IPR036259; PFAM:PF07690; TransMembrane:17 (o12-33i42-61o91-110i122-141o161-188i200-222o249-274i405- 428o448-466i473-493o573-594i615-637o668-688i695-712o718- 739i751-770o776-797i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_51136S COG:G; EggNog:ENOG410QE5R; InterPro:IPR004843,IPR029052; PFAM:PF00149; SECRETED:SignalP(1-25); go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_51137A COG:S; EggNog:ENOG410PS83; InterPro:IPR036908; SECRETED:SignalP(1-21) AKAW2_51138A TransMembrane:2 (n4-12c18/19o42-63i75-97o) AKAW2_51140A COG:F; EggNog:ENOG410PGH5; InterPro:IPR013509,IPR000788,IPR005144,IPR039718, IPR013346,IPR008926; PFAM:PF03477,PF02867,PF00317; go_function: GO:0004748 - ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006260 - DNA replication [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_51141A SECRETED:SignalP(1-22) AKAW2_51142A COG:F,H; EggNog:ENOG410Q19A; InterPro:IPR006083,IPR027417; PFAM:PF00485; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016301 - kinase activity [Evidence IEA] AKAW2_51143A COG:S; EggNog:ENOG410PSNT AKAW2_51144S BUSCO:EOG09260KM4; COG:H; EggNog:ENOG410PH84; InterPro:IPR001645,IPR036615,IPR018109,IPR036565; go_function: GO:0004326 - tetrahydrofolylpolyglutamate synthase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016874 - ligase activity [Evidence IEA]; go_process: GO:0009058 - biosynthetic process [Evidence IEA]; go_process: GO:0009396 - folic acid-containing compound biosynthetic process [Evidence IEA] AKAW2_51145S COG:D; EggNog:ENOG410PG4D; InterPro:IPR016024,IPR011989,IPR008271,IPR017441, IPR000719,IPR011009; PFAM:PF07714,PF00069; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_51146S BUSCO:EOG09261JCQ; COG:S; EggNog:ENOG410PI67; InterPro:IPR011009,IPR004147; PFAM:PF03109; TransMembrane:1 (i106-123o) AKAW2_51147A COG:C; EggNog:ENOG410PNQY; InterPro:IPR002871,IPR011339; PFAM:PF01592; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0051536 - iron-sulfur cluster binding [Evidence IEA]; go_process: GO:0016226 - iron-sulfur cluster assembly [Evidence IEA] AKAW2_51148S TransMembrane:1 (o12-31i) AKAW2_51149A COG:C; EggNog:ENOG410PIKK; InterPro:IPR018108,IPR023395,IPR002067; PFAM:PF00153; TransMembrane:3 (i124-146o166-186i226-248o); go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_51150S BUSCO:EOG09265G9U; COG:C; EggNog:ENOG410PRDI; InterPro:IPR036544,IPR003197; PFAM:PF02271; go_component: GO:0005750 - mitochondrial respiratory chain complex III [Evidence IEA]; go_process: GO:0006122 - mitochondrial electron transport, ubiquinol to cytochrome c [Evidence IEA] AKAW2_51151A BUSCO:EOG09264X9R; COG:L; EggNog:ENOG410PJVX; InterPro:IPR011257,IPR003265; PFAM:PF00730; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_process: GO:0006281 - DNA repair [Evidence IEA]; go_process: GO:0006284 - base-excision repair [Evidence IEA] AKAW2_51152S COG:S; EggNog:ENOG410PNH7; InterPro:IPR032675; PFAM:PF12454; SECRETED:SignalP(1-19) AKAW2_51154S COG:L; EggNog:ENOG410Q1Z8; TransMembrane:1 (o203-222i) AKAW2_51155S CAZy:GT62; COG:S; EggNog:ENOG410PJK0; InterPro:IPR029044; PFAM:PF03452; TransMembrane:1 (o20-46i) AKAW2_51156S COG:S; EggNog:ENOG410PSN8; InterPro:IPR011008,IPR005545; PFAM:PF03795 AKAW2_51157S COG:E; EggNog:ENOG410PW8E; InterPro:IPR037523,IPR041735,IPR041736,IPR029068, IPR004360,IPR005956; PFAM:PF00903; go_function: GO:0003868 - 4-hydroxyphenylpyruvate dioxygenase activity [Evidence IEA]; go_function: GO:0016701 - oxidoreductase activity, acting on single donors with incorporation of molecular oxygen [Evidence IEA]; go_process: GO:0009072 - aromatic amino acid family metabolic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_51158A BUSCO:EOG09261PJZ; COG:L; EggNog:ENOG410PHXY; InterPro:IPR042525,IPR007232,IPR041247,IPR004585; PFAM:PF04098; go_component: GO:0005634 - nucleus [Evidence IEA]; go_process: GO:0000724 - double-strand break repair via homologous recombination [Evidence IEA]; go_process: GO:0000730 - DNA recombinase assembly [Evidence IEA]; go_process: GO:0006281 - DNA repair [Evidence IEA]; go_process: GO:0006310 - DNA recombination [Evidence IEA]; go_process: GO:0045002 - double-strand break repair via single-strand annealing [Evidence IEA] AKAW2_51159A COG:O; EggNog:ENOG410PK3K; InterPro:IPR015940,IPR009060,IPR013087,IPR029071; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_51160S COG:U; EggNog:ENOG410PNHZ; InterPro:IPR013783,IPR016763,IPR000535,IPR008962; PFAM:PF00635; TransMembrane:1 (o265-284i); go_component: GO:0005789 - endoplasmic reticulum membrane [Evidence IEA] AKAW2_51161A COG:I; EggNog:ENOG410PFG5; InterPro:IPR013866,IPR011388,IPR005804; PFAM:PF00487,PF08557; TransMembrane:3 (o83-102i148-168o188-213i); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0042284 - sphingolipid delta-4 desaturase activity [Evidence IEA]; go_process: GO:0006629 - lipid metabolic process [Evidence IEA]; go_process: GO:0030148 - sphingolipid biosynthetic process [Evidence IEA] AKAW2_51162A COG:O; EggNog:ENOG410PI4B; InterPro:IPR036388,IPR000994,IPR036390,IPR002468, IPR036005,IPR001714,IPR018349; MEROPS:MER0001728; PFAM:PF00557; go_function: GO:0070006 - metalloaminopeptidase activity [Evidence IEA]; go_process: GO:0006508 - proteolysis [Evidence IEA] AKAW2_51163S COG:O; EggNog:ENOG410PQU2; InterPro:IPR001623,IPR036869,IPR018253; PFAM:PF00226; TransMembrane:1 (o262-283i) AKAW2_51164A BUSCO:EOG09263OXI; COG:P; EggNog:ENOG410PVZE; InterPro:IPR023614,IPR001925,IPR027246; PFAM:PF01459; go_component: GO:0005741 - mitochondrial outer membrane [Evidence IEA]; go_function: GO:0008308 - voltage-gated anion channel activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA]; go_process: GO:0098656 - anion transmembrane transport [Evidence IEA] AKAW2_51165A COG:E; EggNog:ENOG410PH2V; InterPro:IPR001962,IPR029055,IPR014729,IPR017932; MEROPS:MER0034539; go_function: GO:0004066 - asparagine synthase (glutamine-hydrolyzing) activity [Evidence IEA]; go_process: GO:0006529 - asparagine biosynthetic process [Evidence IEA] AKAW2_51166A COG:O; EggNog:ENOG410PK5S; InterPro:IPR027230,IPR016135,IPR023313,IPR000608; PFAM:PF00179; go_function: GO:0019789 - SUMO transferase activity [Evidence IEA] AKAW2_51167A COG:L; EggNog:ENOG410PJ6D; InterPro:IPR000467,IPR000504,IPR012677,IPR040052, IPR035979; PFAM:PF01585,PF00076; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_process: GO:0043484 - regulation of RNA splicing [Evidence IEA] AKAW2_51168S COG:I; EggNog:ENOG410PIHV; InterPro:IPR000873,IPR020845,IPR042099,IPR025110; PFAM:PF00501,PF13193 AKAW2_51169A COG:S; EggNog:ENOG410PYVX AKAW2_51170A COG:E; EggNog:ENOG410PG2H; InterPro:IPR013057; PFAM:PF01490; TransMembrane:11 (i154-173o179-202i223-248o268-289i301-321o341-362i383- 400o420-439i460-477o483-504i516-538o) AKAW2_51171S COG:S; EggNog:ENOG410Q2QB AKAW2_51172A COG:V; EggNog:ENOG410PQN8; InterPro:IPR020428,IPR029021,IPR016130,IPR004861; PFAM:PF03162; go_function: GO:0004725 - protein tyrosine phosphatase activity [Evidence IEA]; go_function: GO:0016791 - phosphatase activity [Evidence IEA]; go_process: GO:0016311 - dephosphorylation [Evidence IEA] AKAW2_51173A COG:L; EggNog:ENOG410PK4N; InterPro:IPR018228,IPR032466,IPR001130; PFAM:PF01026; go_function: GO:0016788 - hydrolase activity, acting on ester bonds [Evidence IEA]; go_function: GO:0016888 - endodeoxyribonuclease activity, producing 5'-phosphomonoesters [Evidence IEA] AKAW2_51174S COG:S; EggNog:ENOG410Q2S3; InterPro:IPR003034,IPR036361; PFAM:PF02037 AKAW2_51175S COG:O; EggNog:ENOG410PN8W; InterPro:IPR033121,IPR021109,IPR001461,IPR034164; MEROPS:MER0078983; PFAM:PF00026; go_function: GO:0004190 - aspartic-type endopeptidase activity [Evidence IEA]; go_process: GO:0006508 - proteolysis [Evidence IEA] AKAW2_51176A COG:C; EggNog:ENOG410PIMB; InterPro:IPR012133,IPR037396,IPR000262,IPR013785; PFAM:PF01070; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0010181 - FMN binding [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_51177S COG:I; EggNog:ENOG410PFXJ; InterPro:IPR033120,IPR029069 AKAW2_51178S BUSCO:EOG092651K1; COG:S; EggNog:ENOG410PPN4; InterPro:IPR013640; PFAM:PF08432 AKAW2_51180A COG:V; EggNog:ENOG410PHFA; InterPro:IPR020422,IPR016278,IPR029021,IPR016130, IPR000387,IPR000340; PFAM:PF00782; go_function: GO:0004725 - protein tyrosine phosphatase activity [Evidence IEA]; go_function: GO:0008138 - protein tyrosine/serine/threonine phosphatase activity [Evidence IEA]; go_function: GO:0016791 - phosphatase activity [Evidence IEA]; go_process: GO:0006470 - protein dephosphorylation [Evidence IEA]; go_process: GO:0016311 - dephosphorylation [Evidence IEA] AKAW2_51181S COG:S; EggNog:ENOG410PH2E; InterPro:IPR013087 AKAW2_51182A COG:U; EggNog:ENOG410PIF1; InterPro:IPR019049; PFAM:PF09531; TransMembrane:6 (i21-40o46-72i93-113o146-168i213-232o267-288i) AKAW2_51183S COG:U; EggNog:ENOG410PK1B; InterPro:IPR000727,IPR006011,IPR010989,IPR006012; PFAM:PF05739,PF14523; TransMembrane:1 (i252-272o); go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0005484 - SNAP receptor activity [Evidence IEA]; go_process: GO:0006886 - intracellular protein transport [Evidence IEA]; go_process: GO:0016192 - vesicle-mediated transport [Evidence IEA] AKAW2_51184A COG:C,O; EggNog:ENOG410PK4M; InterPro:IPR000511; PFAM:PF01265; go_component: GO:0005739 - mitochondrion [Evidence IEA]; go_function: GO:0004408 - holocytochrome-c synthase activity [Evidence IEA] AKAW2_51185S BUSCO:EOG09263BG5; COG:I; EggNog:ENOG410PG2B; InterPro:IPR006204,IPR036554,IPR020568,IPR005935, IPR041431,IPR029765,IPR014721; PFAM:PF18376,PF00288; go_component: GO:0005829 - cytosol [Evidence IEA]; go_function: GO:0004163 - diphosphomevalonate decarboxylase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016831 - carboxy-lyase activity [Evidence IEA]; go_process: GO:0008299 - isoprenoid biosynthetic process [Evidence IEA]; go_process: GO:0019287 - isopentenyl diphosphate biosynthetic process, mevalonate pathway [Evidence IEA] AKAW2_51186A BUSCO:EOG09260JO5; COG:K; EggNog:ENOG410PG97; InterPro:IPR006849; PFAM:PF04762; go_component: GO:0033588 - Elongator holoenzyme complex [Evidence IEA]; go_process: GO:0002098 - tRNA wobble uridine modification [Evidence IEA] AKAW2_51187A COG:C; EggNog:ENOG410PSIU; InterPro:IPR036636,IPR004202; PFAM:PF02935; TransMembrane:1 (o53-72i); go_function: GO:0004129 - cytochrome-c oxidase activity [Evidence IEA] AKAW2_51188S COG:A; EggNog:ENOG410PHU2; InterPro:IPR012961,IPR016438,IPR027417,IPR001650, IPR014001,IPR011545,IPR025696; PFAM:PF04851,PF13234,PF08148,PF00270,PF00271; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0003723 - RNA binding [Evidence IEA]; go_function: GO:0003724 - RNA helicase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006401 - RNA catabolic process [Evidence IEA] AKAW2_51189S COG:U; EggNog:ENOG410PKVS; InterPro:IPR013868,IPR038422; PFAM:PF08559; go_component: GO:0005634 - nucleus [Evidence IEA]; go_process: GO:0031144 - proteasome localization [Evidence IEA]; go_process: GO:0071630 - nuclear protein quality control by the ubiquitin-proteasome system [Evidence IEA] AKAW2_51190A COG:S; EggNog:ENOG410PI63; InterPro:IPR025040; PFAM:PF13136 AKAW2_51191S COG:S; EggNog:ENOG410PK4U; InterPro:IPR022185; PFAM:PF12505; TransMembrane:1 (i92-114o) AKAW2_51192A BUSCO:EOG09263MGE; COG:E; EggNog:ENOG410PH1Y; InterPro:IPR039557,IPR004789,IPR019455,IPR002912, IPR027271; PFAM:PF01842,PF10369,PF13710; go_function: GO:1990610 - acetolactate synthase regulator activity [Evidence IEA]; go_process: GO:0009082 - branched-chain amino acid biosynthetic process [Evidence IEA] AKAW2_51193S COG:A; EggNog:ENOG410PIMI; InterPro:IPR004087,IPR004088,IPR031121,IPR036612; PFAM:PF00013; go_component: GO:0005634 - nucleus [Evidence IEA]; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0003723 - RNA binding [Evidence IEA] AKAW2_51194A COG:S; EggNog:ENOG410PMCX; InterPro:IPR002885,IPR011990; PFAM:PF01535; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_51195S BUSCO:EOG09264X41; COG:J; EggNog:ENOG410Q16Q; InterPro:IPR016939; PFAM:PF13741; go_component: GO:0005763 - mitochondrial small ribosomal subunit [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA] AKAW2_51196S COG:T; EggNog:ENOG410PMC7; InterPro:IPR019487,IPR001611,IPR003591,IPR017241, IPR032675; PFAM:PF10428,PF13855; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0004888 - transmembrane signaling receptor activity [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0002224 - toll-like receptor signaling pathway [Evidence IEA]; go_process: GO:0006955 - immune response [Evidence IEA] AKAW2_51198S COG:T; EggNog:ENOG410PI2G; InterPro:IPR008862; PFAM:PF05794; TransMembrane:1 (o375-391i) AKAW2_51199A COG:S; EggNog:ENOG410Q25Y; SECRETED:SignalP(1-21) AKAW2_51200S COG:S; EggNog:ENOG410PP04; InterPro:IPR014729,IPR005248; go_function: GO:0016779 - nucleotidyltransferase activity [Evidence IEA]; go_process: GO:0009435 - NAD biosynthetic process [Evidence IEA] AKAW2_51201A COG:S; EggNog:ENOG410PXGM; TransMembrane:3 (i46-63o69-85i105-124o) AKAW2_51202S COG:O; EggNog:ENOG410PIVI; InterPro:IPR001623,IPR036869,IPR015399,IPR018253; PFAM:PF00226,PF09320; TransMembrane:1 (o219-238i) AKAW2_51203S BUSCO:EOG09260NWN; COG:O; EggNog:ENOG410PGAX; InterPro:IPR019474,IPR013083,IPR003613; PFAM:PF10408,PF04564; go_component: GO:0000151 - ubiquitin ligase complex [Evidence IEA]; go_function: GO:0004842 - ubiquitin-protein transferase activity [Evidence IEA]; go_function: GO:0034450 - ubiquitin-ubiquitin ligase activity [Evidence IEA]; go_process: GO:0006511 - ubiquitin-dependent protein catabolic process [Evidence IEA]; go_process: GO:0016567 - protein ubiquitination [Evidence IEA] AKAW2_51204S COG:I; EggNog:ENOG410PMEG; InterPro:IPR001104,IPR039357; TransMembrane:5 (o24-45i66-84o104-123i135-159o188-207i); go_function: GO:0016627 - oxidoreductase activity, acting on the CH-CH group of donors [Evidence IEA]; go_process: GO:0006629 - lipid metabolic process [Evidence IEA] AKAW2_51205A COG:E; EggNog:ENOG410PHAS; InterPro:IPR002629,IPR013215,IPR038071,IPR006276; PFAM:PF01717,PF08267; go_function: GO:0003871 - 5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0008652 - cellular amino acid biosynthetic process [Evidence IEA]; go_process: GO:0009086 - methionine biosynthetic process [Evidence IEA] AKAW2_51206S COG:S; EggNog:ENOG410PZ0A AKAW2_51207A BUSCO:EOG09262OLP; COG:B; EggNog:ENOG410PK52; InterPro:IPR008468,IPR027109,IPR017877,IPR032563; PFAM:PF16282,PF05499; go_component: GO:0005634 - nucleus [Evidence IEA]; go_component: GO:0035267 - NuA4 histone acetyltransferase complex [Evidence IEA]; go_process: GO:0006281 - DNA repair [Evidence IEA]; go_process: GO:0006338 - chromatin remodeling [Evidence IEA]; go_process: GO:0043967 - histone H4 acetylation [Evidence IEA]; go_process: GO:0043968 - histone H2A acetylation [Evidence IEA]; go_process: GO:0045892 - negative regulation of transcription, DNA-templated [Evidence IEA] AKAW2_51208S COG:U; EggNog:ENOG410PKS7; InterPro:IPR015720,IPR009038; PFAM:PF01105; SECRETED:SignalP(1-29); TransMembrane:1 (n14-25c29/30o200-220i) AKAW2_51209A COG:T; EggNog:ENOG410PJW2; InterPro:IPR001789,IPR003594,IPR003661,IPR036890, IPR011006,IPR004358,IPR005467; PFAM:PF02518; go_function: GO:0000155 - phosphorelay sensor kinase activity [Evidence IEA]; go_function: GO:0016772 - transferase activity, transferring phosphorus-containing groups [Evidence IEA]; go_process: GO:0000160 - phosphorelay signal transduction system [Evidence IEA]; go_process: GO:0007165 - signal transduction [Evidence IEA]; go_process: GO:0016310 - phosphorylation [Evidence IEA] AKAW2_51210A BUSCO:EOG09264G4X; COG:O; EggNog:ENOG410PHSV; InterPro:IPR029055,IPR001353,IPR023333,IPR033811, IPR016050; MEROPS:MER0001710; PFAM:PF00227; go_component: GO:0005839 - proteasome core complex [Evidence IEA]; go_component: GO:0019774 - proteasome core complex, beta-subunit complex [Evidence IEA]; go_function: GO:0004298 - threonine-type endopeptidase activity [Evidence IEA]; go_process: GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process [Evidence IEA]; go_process: GO:0051603 - proteolysis involved in cellular protein catabolic process [Evidence IEA] AKAW2_51211S COG:O; EggNog:ENOG410PKFW; InterPro:IPR029071,IPR001012,IPR021569; PFAM:PF11470,PF00789; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_51212A COG:J; EggNog:ENOG410PPM7; InterPro:IPR038097,IPR000509; PFAM:PF01158; go_component: GO:0005840 - ribosome [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_process: GO:0006412 - translation [Evidence IEA] AKAW2_51213A COG:J; EggNog:ENOG410PPM7; TransMembrane:7 (o26-46i58-76o107-125i137-160o180-205i217-237o257-280i) AKAW2_51214A COG:Z; EggNog:ENOG410PP7U; InterPro:IPR019183; PFAM:PF09797 AKAW2_51215A COG:O; EggNog:ENOG410PQT9; InterPro:IPR009069 AKAW2_51216S COG:S; EggNog:ENOG410PIY1 AKAW2_51217S COG:O; EggNog:ENOG410PQ29; InterPro:IPR001841,IPR017907,IPR018957,IPR013083; PFAM:PF13923,PF13920,PF00097,PF13445,PF13639; go_function: GO:0046872 - metal ion binding [Evidence IEA] AKAW2_51218A COG:A; EggNog:ENOG410PFHE; InterPro:IPR036322,IPR001680,IPR019775,IPR020472, IPR039241,IPR017986; PFAM:PF00400; go_function: GO:0005515 - protein binding [Evidence IEA]; go_function: GO:0034511 - U3 snoRNA binding [Evidence IEA]; go_process: GO:0006364 - rRNA processing [Evidence IEA] AKAW2_51219S COG:O; EggNog:ENOG410PHXK; InterPro:IPR035206,IPR029055,IPR001353,IPR023333; MEROPS:MER0002676; PFAM:PF00227; go_component: GO:0005839 - proteasome core complex [Evidence IEA]; go_function: GO:0004298 - threonine-type endopeptidase activity [Evidence IEA]; go_process: GO:0051603 - proteolysis involved in cellular protein catabolic process [Evidence IEA] AKAW2_51220S BUSCO:EOG09262QL6; COG:Z; EggNog:ENOG410PG9J; InterPro:IPR033809,IPR001607,IPR001394,IPR038765, IPR028889,IPR013083; MEROPS:MER0064621; PFAM:PF02148,PF00443; go_function: GO:0004843 - thiol-dependent ubiquitin-specific protease activity [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0000245 - spliceosomal complex assembly [Evidence IEA]; go_process: GO:0006397 - mRNA processing [Evidence IEA]; go_process: GO:0016579 - protein deubiquitination [Evidence IEA] AKAW2_51221A COG:S; EggNog:ENOG410PQ8K AKAW2_51222S COG:A; EggNog:ENOG410PHWK; InterPro:IPR036322,IPR015943,IPR001680,IPR019775, IPR020472,IPR013934,IPR017986; PFAM:PF08625,PF00400; go_component: GO:0032040 - small-subunit processome [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0006364 - rRNA processing [Evidence IEA] AKAW2_51223A COG:A; EggNog:ENOG410PS3I; InterPro:IPR000467,IPR026822; PFAM:PF12656; go_function: GO:0003676 - nucleic acid binding [Evidence IEA] AKAW2_51224A BUSCO:EOG09261DG0; COG:B; EggNog:ENOG410PG7Z; InterPro:IPR009057,IPR017877,IPR001005,IPR014012; PFAM:PF13921,PF07529 AKAW2_51225S COG:G; EggNog:ENOG410PFBJ; InterPro:IPR015943,IPR001680,IPR036322; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_51226S BUSCO:EOG09261TPN; COG:J; EggNog:ENOG410PFEJ; InterPro:IPR027417,IPR000795,IPR004161,IPR044128, IPR015256,IPR044127,IPR009001,IPR009000; PFAM:PF00009,PF03144,PF09173; go_function: GO:0000049 - tRNA binding [Evidence IEA]; go_function: GO:0003924 - GTPase activity [Evidence IEA]; go_function: GO:0005525 - GTP binding [Evidence IEA] AKAW2_51227S COG:O; EggNog:ENOG410PFIX; InterPro:IPR001915,IPR027057,IPR032456; MEROPS:MER0002635; PFAM:PF01435,PF16491; TransMembrane:5 (o20-38i123-143o169-188i195-222o310-329i); go_function: GO:0004222 - metalloendopeptidase activity [Evidence IEA]; go_function: GO:0008233 - peptidase activity [Evidence IEA]; go_process: GO:0006508 - proteolysis [Evidence IEA]; go_process: GO:0071586 - CAAX-box protein processing [Evidence IEA] AKAW2_51228A COG:S; EggNog:ENOG410PU3A AKAW2_51229S COG:J; EggNog:ENOG410Q084; InterPro:IPR000271; PFAM:PF00468; go_component: GO:0005840 - ribosome [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_process: GO:0006412 - translation [Evidence IEA] AKAW2_51230A BUSCO:EOG09260DFH; COG:O; EggNog:ENOG410PF9R; InterPro:IPR007863,IPR011249,IPR011765; MEROPS:MER0003909; PFAM:PF00675,PF05193; go_function: GO:0046872 - metal ion binding [Evidence IEA] AKAW2_51231S COG:D; EggNog:ENOG410PK24; InterPro:IPR009361; PFAM:PF06248; go_component: GO:0000775 - chromosome, centromeric region [Evidence IEA]; go_component: GO:0005634 - nucleus [Evidence IEA]; go_process: GO:0000278 - mitotic cell cycle [Evidence IEA] AKAW2_51232S COG:J; EggNog:ENOG410PHJB; InterPro:IPR012972,IPR036322,IPR015943,IPR001680, IPR028599,IPR019775,IPR020472,IPR017986; PFAM:PF08154,PF00400; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0042254 - ribosome biogenesis [Evidence IEA] AKAW2_51233A COG:J; EggNog:ENOG410PRC7; InterPro:IPR010979,IPR001892,IPR019980,IPR018269, IPR027437; go_component: GO:0005840 - ribosome [Evidence IEA]; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0003723 - RNA binding [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_process: GO:0006412 - translation [Evidence IEA] AKAW2_51234S COG:O; EggNog:ENOG410PFKS; InterPro:IPR024936,IPR029000,IPR020892,IPR002130; PFAM:PF00160; SECRETED:SignalP(1-23); go_function: GO:0003755 - peptidyl-prolyl cis-trans isomerase activity [Evidence IEA]; go_process: GO:0000413 - protein peptidyl-prolyl isomerization [Evidence IEA]; go_process: GO:0006457 - protein folding [Evidence IEA] AKAW2_51235S COG:J; EggNog:ENOG410Q803; InterPro:IPR027417,IPR001650,IPR014014,IPR014001, IPR011545,IPR000629; PFAM:PF00270,PF00271; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0004386 - helicase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA] AKAW2_51236S COG:S; EggNog:ENOG410PMAX; InterPro:IPR038014; go_component: GO:0031011 - Ino80 complex [Evidence IEA] AKAW2_51237S COG:S; EggNog:ENOG410PNA8; InterPro:IPR025929; PFAM:PF07281; TransMembrane:6 (i124-144o164-184i211-231o237-256i263-280o316-336i) AKAW2_51238S COG:F; EggNog:ENOG410PFH2; InterPro:IPR011607,IPR036914,IPR002695,IPR016193, IPR024051,IPR024050; PFAM:PF01808,PF02142; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0003937 - IMP cyclohydrolase activity [Evidence IEA]; go_function: GO:0004643 - phosphoribosylaminoimidazolecarboxamide formyltransferase activity [Evidence IEA]; go_process: GO:0006164 - purine nucleotide biosynthetic process [Evidence IEA] AKAW2_51239S BUSCO:EOG092602BZ; COG:U; EggNog:ENOG410PIM9; InterPro:IPR016025,IPR016024,IPR011990,IPR016341, IPR022365,IPR000547; PFAM:PF01394,PF13838,PF00637; go_component: GO:0030130 - clathrin coat of trans-Golgi network vesicle [Evidence IEA]; go_component: GO:0030132 - clathrin coat of coated pit [Evidence IEA]; go_component: GO:0071439 - clathrin complex [Evidence IEA]; go_function: GO:0005198 - structural molecule activity [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_function: GO:0032051 - clathrin light chain binding [Evidence IEA]; go_process: GO:0006886 - intracellular protein transport [Evidence IEA]; go_process: GO:0016192 - vesicle-mediated transport [Evidence IEA] AKAW2_51240S COG:C; EggNog:ENOG410Q5AY; InterPro:IPR003379,IPR011054,IPR011053,IPR005479, IPR013785,IPR001882,IPR000089,IPR000891,IPR005930, IPR011761,IPR016185,IPR011764,IPR005482,IPR005481; PFAM:PF00682,PF02436,PF13533,PF02222,PF00364, PF02785,PF02786,PF00289,PF07478; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0004736 - pyruvate carboxylase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0009374 - biotin binding [Evidence IEA]; go_function: GO:0046872 - metal ion binding [Evidence IEA]; go_process: GO:0006090 - pyruvate metabolic process [Evidence IEA]; go_process: GO:0006094 - gluconeogenesis [Evidence IEA] AKAW2_51241A COG:I; EggNog:ENOG410PKEN; InterPro:IPR019826,IPR002018,IPR029058; MEROPS:MER0034664; PFAM:PF00135 AKAW2_51242S COG:S; EggNog:ENOG410PTWP AKAW2_51243A BUSCO:EOG09264X8J; COG:J; EggNog:ENOG410PGC7; InterPro:IPR031310,IPR002132,IPR022803,IPR031309, IPR020929; PFAM:PF00281,PF00673; go_component: GO:0005840 - ribosome [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_process: GO:0006412 - translation [Evidence IEA] AKAW2_51244S COG:A; EggNog:ENOG410PPAD; InterPro:IPR010920,IPR001163; PFAM:PF01423 AKAW2_51245S COG:A; EggNog:ENOG410PP7Y; InterPro:IPR005336; PFAM:PF03650; go_component: GO:0005743 - mitochondrial inner membrane [Evidence IEA]; go_process: GO:0006850 - mitochondrial pyruvate transmembrane transport [Evidence IEA] AKAW2_51246A COG:E; EggNog:ENOG410PFBU; InterPro:IPR013057; PFAM:PF01490; TransMembrane:11 (i355-376o382-403i428-446o466-484i491-512o532-554i566- 590o610-635i656-673o679-700i712-733o) AKAW2_51247S COG:P; EggNog:ENOG410PGPN; InterPro:IPR004841,IPR018491; PFAM:PF13520,PF00324; TransMembrane:11 (i135-156o168-191i203-226o264-285i292-310o356-377i389- 411o431-459i480-497o503-524i544-577o); go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0006811 - ion transport [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_51248A COG:I; EggNog:ENOG410Q20Y; InterPro:IPR006176,IPR022694,IPR006108,IPR036291, IPR008927,IPR013328; PFAM:PF02737,PF00725; go_function: GO:0003857 - 3-hydroxyacyl-CoA dehydrogenase activity [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0070403 - NAD+ binding [Evidence IEA]; go_process: GO:0006631 - fatty acid metabolic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_51249S COG:I; EggNog:ENOG410PIG8; InterPro:IPR013750,IPR006203,IPR006204,IPR006205, IPR036554,IPR020568,IPR014721; PFAM:PF00288,PF08544; go_component: GO:0005737 - cytoplasm [Evidence IEA]; go_function: GO:0004496 - mevalonate kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0008299 - isoprenoid biosynthetic process [Evidence IEA] AKAW2_51250A COG:S; EggNog:ENOG410PPS4; InterPro:IPR036864,IPR021858,IPR001138; PFAM:PF00172,PF11951; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_51251S BUSCO:EOG09263Z41; COG:O; EggNog:ENOG410PGF8; InterPro:IPR002088; PFAM:PF01239; go_function: GO:0008318 - protein prenyltransferase activity [Evidence IEA]; go_process: GO:0018342 - protein prenylation [Evidence IEA] AKAW2_51252A COG:E; EggNog:ENOG410PGFY; InterPro:IPR036052,IPR000634,IPR001926; PFAM:PF00291; go_function: GO:0030170 - pyridoxal phosphate binding [Evidence IEA]; go_process: GO:0006520 - cellular amino acid metabolic process [Evidence IEA] AKAW2_51253A BUSCO:EOG09263NXM; COG:J; EggNog:ENOG410PG4Y; InterPro:IPR041872,IPR009080,IPR014758,IPR033911, IPR015413,IPR014729; PFAM:PF09334; go_function: GO:0000166 - nucleotide binding [Evidence IEA]; go_function: GO:0004812 - aminoacyl-tRNA ligase activity [Evidence IEA]; go_function: GO:0004825 - methionine-tRNA ligase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006418 - tRNA aminoacylation for protein translation [Evidence IEA]; go_process: GO:0006431 - methionyl-tRNA aminoacylation [Evidence IEA] AKAW2_51254S COG:A; EggNog:ENOG410PSN2; InterPro:IPR018222,IPR032710,IPR002075; PFAM:PF02136 AKAW2_51255A COG:S; EggNog:ENOG410PS7F; TransMembrane:1 (i12-31o) AKAW2_51256S BUSCO:EOG09265OQH; COG:J; EggNog:ENOG410PS41; InterPro:IPR002675,IPR038464; PFAM:PF01781; go_component: GO:0005840 - ribosome [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_process: GO:0006412 - translation [Evidence IEA] AKAW2_51257A COG:G; EggNog:ENOG410PP4B; InterPro:IPR000182,IPR039135,IPR016181; PFAM:PF13302; go_function: GO:0008080 - N-acetyltransferase activity [Evidence IEA]; go_function: GO:0016747 - transferase activity, transferring acyl groups other than amino-acyl groups [Evidence IEA] AKAW2_51258A BUSCO:EOG09263CUU; COG:L; EggNog:ENOG410PFYC; InterPro:IPR041863,IPR007185,IPR024826,IPR040663; PFAM:PF18018,PF04042; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_process: GO:0006260 - DNA replication [Evidence IEA] AKAW2_51259S TransMembrane:2 (o14-33i144-161o) AKAW2_51260S COG:S; EggNog:ENOG410PIPT; InterPro:IPR013785,IPR004136; PFAM:PF03060,PF00478; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0018580 - nitronate monooxygenase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_51261A COG:Z; EggNog:ENOG410PK98; InterPro:IPR026183; PFAM:PF09728; go_function: GO:0019905 - syntaxin binding [Evidence IEA] AKAW2_51262S COG:O; EggNog:ENOG410PH5B; InterPro:IPR013578,IPR007863,IPR011249; MEROPS:MER0015270; PFAM:PF05193,PF08367; go_function: GO:0046872 - metal ion binding [Evidence IEA]; go_process: GO:0006508 - proteolysis [Evidence IEA] AKAW2_51263S COG:S; EggNog:ENOG410PUGW AKAW2_51264A COG:S; EggNog:ENOG410PJNN AKAW2_51265S COG:A; EggNog:ENOG410PQ0E; InterPro:IPR029063,IPR019410; PFAM:PF10294,PF13847 AKAW2_51266A COG:I; EggNog:ENOG410PNHB; InterPro:IPR029058,IPR013094; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_51267A COG:S; EggNog:ENOG410PZ3A AKAW2_51268S COG:O; EggNog:ENOG410PPBF; InterPro:IPR036249,IPR014440,IPR001853; PFAM:PF01323; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA] AKAW2_51270A COG:T; EggNog:ENOG410PWKG; InterPro:IPR000719,IPR011009; PFAM:PF07714,PF00069; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_51271S COG:H; EggNog:ENOG410PFU1; InterPro:IPR027417,IPR003495; PFAM:PF02492 AKAW2_51272A BUSCO:EOG09261V03; COG:E; EggNog:ENOG410PGWB; InterPro:IPR022644,IPR022643,IPR022653,IPR002433, IPR029066,IPR022657,IPR009006,IPR000183; PFAM:PF00278,PF02784; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_process: GO:0006596 - polyamine biosynthetic process [Evidence IEA] AKAW2_51274A COG:S; EggNog:ENOG410PMG0; InterPro:IPR038769; TransMembrane:1 (o1193-1214i) AKAW2_51275A COG:M; EggNog:ENOG410PFS9; InterPro:IPR019133; TransMembrane:1 (i104-124o) AKAW2_51276A COG:U; EggNog:ENOG410PG62; InterPro:IPR005225,IPR001806,IPR027417; PFAM:PF04670,PF00025,PF08477,PF00071,PF01926; go_function: GO:0003924 - GTPase activity [Evidence IEA]; go_function: GO:0005525 - GTP binding [Evidence IEA] AKAW2_51277S COG:I; EggNog:ENOG410PGMX; InterPro:IPR002013; PFAM:PF02383; TransMembrane:2 (o590-611i623-642o); go_function: GO:0042578 - phosphoric ester hydrolase activity [Evidence IEA] AKAW2_51278S COG:H; EggNog:ENOG410PHKQ; InterPro:IPR001645,IPR036615,IPR018109,IPR023600, IPR036565; go_function: GO:0004326 - tetrahydrofolylpolyglutamate synthase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016874 - ligase activity [Evidence IEA]; go_process: GO:0009058 - biosynthetic process [Evidence IEA]; go_process: GO:0009396 - folic acid-containing compound biosynthetic process [Evidence IEA] AKAW2_51279S BUSCO:EOG09261SS1; COG:I; EggNog:ENOG410PIAT; InterPro:IPR022678,IPR022677,IPR022676,IPR016181, IPR000903; PFAM:PF02799,PF01233; go_function: GO:0004379 - glycylpeptide N-tetradecanoyltransferase activity [Evidence IEA]; go_process: GO:0006499 - N-terminal protein myristoylation [Evidence IEA] AKAW2_51280S COG:O; EggNog:ENOG410PIPH; InterPro:IPR006571; PFAM:PF07534 AKAW2_51281A COG:Q; EggNog:ENOG410PQ52; InterPro:IPR029063,IPR041698; PFAM:PF08241,PF13649 AKAW2_51282A COG:S; EggNog:ENOG410PNBA; InterPro:IPR037651; go_component: GO:0000812 - Swr1 complex [Evidence IEA]; go_process: GO:0006338 - chromatin remodeling [Evidence IEA]; go_process: GO:0043486 - histone exchange [Evidence IEA] AKAW2_51283S COG:S; EggNog:ENOG410PVX2; InterPro:IPR000073,IPR029058; MEROPS:MER0017243; PFAM:PF12697; TransMembrane:1 (i12-34o) AKAW2_51284A COG:J; EggNog:ENOG410PGGK; InterPro:IPR004540,IPR005517,IPR035647,IPR005225, IPR031157,IPR041095,IPR027417,IPR000640,IPR000795, IPR004161,IPR009022,IPR020568,IPR014721,IPR009000; PFAM:PF14492,PF03764,PF00009,PF00679,PF03144; go_function: GO:0003746 - translation elongation factor activity [Evidence IEA]; go_function: GO:0003924 - GTPase activity [Evidence IEA]; go_function: GO:0005525 - GTP binding [Evidence IEA]; go_process: GO:0006414 - translational elongation [Evidence IEA] AKAW2_51285S COG:S; EggNog:ENOG410PS7B; InterPro:IPR008011; PFAM:PF13233,PF05347 AKAW2_51286A BUSCO:EOG09264J8E; COG:M; EggNog:ENOG410PR45; InterPro:IPR007667; PFAM:PF04588; TransMembrane:2 (i33-49o69-86i) AKAW2_51287S BUSCO:EOG09261O4Y; COG:E; EggNog:ENOG410PFIF; InterPro:IPR038110,IPR005787,IPR001926,IPR036052, IPR000634,IPR001721; PFAM:PF00291,PF00585; go_function: GO:0004794 - L-threonine ammonia-lyase activity [Evidence IEA]; go_function: GO:0030170 - pyridoxal phosphate binding [Evidence IEA]; go_process: GO:0006520 - cellular amino acid metabolic process [Evidence IEA]; go_process: GO:0009097 - isoleucine biosynthetic process [Evidence IEA] AKAW2_51288S COG:J; EggNog:ENOG410PTCU; InterPro:IPR000473,IPR035977; PFAM:PF00444; go_component: GO:0005840 - ribosome [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_process: GO:0006412 - translation [Evidence IEA] AKAW2_51289S COG:S; EggNog:ENOG410PHNG; InterPro:IPR016274,IPR033379,IPR000560,IPR029033; PFAM:PF00328; SECRETED:SignalP(1-19); go_function: GO:0016791 - phosphatase activity [Evidence IEA] AKAW2_51290A COG:C; EggNog:ENOG410PFH7; InterPro:IPR010102,IPR015590,IPR016160,IPR016161, IPR016162,IPR016163; PFAM:PF00171; go_function: GO:0009013 - succinate-semialdehyde dehydrogenase [NAD(P)+] activity [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0016620 - oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Evidence IEA]; go_process: GO:0009450 - gamma-aminobutyric acid catabolic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_51291A COG:S; EggNog:ENOG410PQ73; InterPro:IPR019622; PFAM:PF10680 AKAW2_51292A BUSCO:EOG09261L4M; COG:J; EggNog:ENOG410PH1N; InterPro:IPR036420,IPR001357,IPR010613; PFAM:PF06732; go_component: GO:0005730 - nucleolus [Evidence IEA]; go_process: GO:0042254 - ribosome biogenesis [Evidence IEA] AKAW2_51293S BUSCO:EOG09262O0R; COG:G; EggNog:ENOG410PHWS; InterPro:IPR009600; PFAM:PF06728; SECRETED:SignalP(1-34); TransMembrane:8 (o6-25i134-165o177-202i223-248o268-295i307-325o345- 367i379-404o); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_component: GO:0042765 - GPI-anchor transamidase complex [Evidence IEA]; go_process: GO:0016255 - attachment of GPI anchor to protein [Evidence IEA] AKAW2_51294A COG:S; EggNog:ENOG410PRMC; InterPro:IPR016181,IPR039949,IPR000182; PFAM:PF13673,PF13508,PF08445,PF00583; go_function: GO:0008080 - N-acetyltransferase activity [Evidence IEA]; go_function: GO:0010485 - H4 histone acetyltransferase activity [Evidence IEA]; go_function: GO:0043998 - H2A histone acetyltransferase activity [Evidence IEA] AKAW2_51295A COG:C; EggNog:ENOG410PFVQ; InterPro:IPR018170,IPR020471,IPR036812,IPR023210; PFAM:PF00248; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_51296S COG:Q; EggNog:ENOG410PHTQ; InterPro:IPR013154,IPR013149,IPR036291,IPR011032, IPR020843; PFAM:PF00107,PF08240,PF13602; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_51297S COG:S; EggNog:ENOG410PGI5; InterPro:IPR017853,IPR008811,IPR013785; go_function: GO:0003824 - catalytic activity [Evidence IEA] AKAW2_51298A COG:Q; EggNog:ENOG410PHJC; InterPro:IPR004294; PFAM:PF03055; go_function: GO:0016702 - oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_51300A COG:S; EggNog:ENOG410PSA2 AKAW2_51301A COG:G; EggNog:ENOG410QEH0; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:10 (o45-68i113-134o206-228i263-284o304-325i332-352o358- 377i389-411o431-455i489-511o); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_51302S COG:L; EggNog:ENOG410PQK2; InterPro:IPR012337,IPR036397,IPR002156; PFAM:PF00075; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0004523 - RNA-DNA hybrid ribonuclease activity [Evidence IEA] AKAW2_51303A COG:S; EggNog:ENOG410Q0BK AKAW2_51306S COG:M; EggNog:ENOG410PGZH; InterPro:IPR029065,IPR034593,IPR036849,IPR013342, IPR013341,IPR029017,IPR018110; PFAM:PF13378,PF02746; go_process: GO:0009063 - cellular amino acid catabolic process [Evidence IEA] AKAW2_51307S COG:Q; EggNog:ENOG410PHW8; InterPro:IPR002347,IPR036291,IPR020904; PFAM:PF00106,PF13561,PF08659,PF01370; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_51308S COG:S; EggNog:ENOG410PIYI; InterPro:IPR011118,IPR029058; PFAM:PF07519; SECRETED:SignalP(1-16) AKAW2_51309S COG:S; EggNog:ENOG410Q1B8 AKAW2_51310S COG:E; EggNog:ENOG410PJ7Z; InterPro:IPR020846,IPR005828,IPR036259; PFAM:PF00083; TransMembrane:11 (o15-38i45-66o72-92i104-125o137-156i226-252o264-285i292- 316o322-341i362-380o392-411i); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_51311S COG:E; EggNog:ENOG410PVD9; InterPro:IPR028939,IPR036291,IPR000304,IPR029036, IPR008927; PFAM:PF03807,PF14748; go_function: GO:0004735 - pyrroline-5-carboxylate reductase activity [Evidence IEA]; go_process: GO:0006561 - proline biosynthetic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_51312A COG:G; EggNog:ENOG410QDJA; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i57-74o98-120i127-146o152-177i189-208o220-240i288- 313o325-344i356-374o380-403i415-435o447-470i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_51313S COG:C; EggNog:ENOG410PUJW; InterPro:IPR037458,IPR001199,IPR037396,IPR013785, IPR036400,IPR000262,IPR018506; PFAM:PF00173; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA] AKAW2_51314S CAZy:CE10; COG:O; EggNog:ENOG410PH95; InterPro:IPR001375,IPR029058,IPR011042; MEROPS:MER0018170; PFAM:PF01738,PF00326,PF08840; go_function: GO:0008236 - serine-type peptidase activity [Evidence IEA]; go_process: GO:0006508 - proteolysis [Evidence IEA] AKAW2_51316S COG:S; EggNog:ENOG410PNG7; TransMembrane:7 (o20-40i47-66o78-96i117-136o161-180i192-211o231-250i) AKAW2_51315A COG:O; EggNog:ENOG410PJ5M; InterPro:IPR007484,IPR037457,IPR040234; MEROPS:MER0015095; PFAM:PF04389; SECRETED:SignalP(1-27); go_function: GO:0016603 - glutaminyl-peptide cyclotransferase activity [Evidence IEA] AKAW2_51317S COG:S; EggNog:ENOG410PRV3; TransMembrane:2 (i97-115o127-152i) AKAW2_51318S COG:B; EggNog:ENOG410Q1K6 AKAW2_51319A SECRETED:SignalP(1-21) AKAW2_51320A COG:Q; EggNog:ENOG410Q21Z; InterPro:IPR036188; PFAM:PF00743,PF13738,PF07992 AKAW2_51321A CAZy:AA3; COG:E; EggNog:ENOG410PFGF; InterPro:IPR012132,IPR036188,IPR000172,IPR007867; PFAM:PF05199,PF00732; go_function: GO:0016614 - oxidoreductase activity, acting on CH-OH group of donors [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_51322A COG:C; EggNog:ENOG410PIAC; InterPro:IPR006094,IPR036318,IPR016166,IPR012951; PFAM:PF08031,PF01565; SECRETED:SignalP(1-18); go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_function: GO:0071949 - FAD binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_51323A COG:S; EggNog:ENOG410PPRF; InterPro:IPR002110,IPR036770,IPR020683; PFAM:PF13857,PF12796,PF00023,PF13637,PF13606; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_51324A COG:S; EggNog:ENOG410PRQK; InterPro:IPR021054; PFAM:PF12296; SECRETED:SignalP(1-19) AKAW2_51327A BUSCO:EOG09260DP1; COG:L; EggNog:ENOG410PH6E; InterPro:IPR027417,IPR036678,IPR036187,IPR017261, IPR007861,IPR016151,IPR000432,IPR007695,IPR007696, IPR007860; PFAM:PF05188,PF05190,PF05192,PF00488,PF01624; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0030983 - mismatched DNA binding [Evidence IEA]; go_process: GO:0006298 - mismatch repair [Evidence IEA] AKAW2_51328A BUSCO:EOG09262JRP; COG:J; EggNog:ENOG410PH73; InterPro:IPR036986,IPR024088,IPR001412,IPR032005, IPR014729,IPR002305,IPR002307; PFAM:PF16714,PF00579; go_function: GO:0000166 - nucleotide binding [Evidence IEA]; go_function: GO:0003723 - RNA binding [Evidence IEA]; go_function: GO:0004812 - aminoacyl-tRNA ligase activity [Evidence IEA]; go_function: GO:0004831 - tyrosine-tRNA ligase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006418 - tRNA aminoacylation for protein translation [Evidence IEA]; go_process: GO:0006437 - tyrosyl-tRNA aminoacylation [Evidence IEA] AKAW2_51329S COG:S; EggNog:ENOG410PPFR; InterPro:IPR031760,IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; TransMembrane:2 (i209-226o525-546i); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_51330A COG:G; EggNog:ENOG410PI0M; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i68-88o108-128i135-156o168-187i194-217o223-243i318- 340o360-381i402-422o434-455i467-488o500-525i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_51331A COG:S; EggNog:ENOG410PVM5; InterPro:IPR008775; PFAM:PF05721 AKAW2_51332S COG:S; EggNog:ENOG410PK74; InterPro:IPR008979,IPR029058,IPR005674,IPR013736, IPR000383; PFAM:PF02129,PF08530; go_function: GO:0008239 - dipeptidyl-peptidase activity [Evidence IEA]; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_51333S BUSCO:EOG09261Q18; COG:J; EggNog:ENOG410PG5R; InterPro:IPR006195,IPR012340,IPR004115,IPR004364, IPR002312,IPR004524; PFAM:PF00152; go_component: GO:0005737 - cytoplasm [Evidence IEA]; go_function: GO:0000166 - nucleotide binding [Evidence IEA]; go_function: GO:0004812 - aminoacyl-tRNA ligase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016874 - ligase activity [Evidence IEA]; go_process: GO:0006418 - tRNA aminoacylation for protein translation [Evidence IEA] AKAW2_51334A COG:H; EggNog:ENOG410PFA5; InterPro:IPR030470,IPR006369,IPR016315,IPR000537; PFAM:PF01040; TransMembrane:8 (i178-196o216-239i260-282o288-306i313-334o354-374i407- 437o457-475i); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_component: GO:0031966 - mitochondrial membrane [Evidence IEA]; go_function: GO:0008495 - protoheme IX farnesyltransferase activity [Evidence IEA]; go_function: GO:0016765 - transferase activity, transferring alkyl or aryl (other than methyl) groups [Evidence IEA]; go_process: GO:0006783 - heme biosynthetic process [Evidence IEA]; go_process: GO:0048034 - heme O biosynthetic process [Evidence IEA] AKAW2_51335S COG:S; EggNog:ENOG410PJ42; InterPro:IPR016817,IPR006603; PFAM:PF04193; TransMembrane:4 (i90-112o118-139i146-164o232-255i) AKAW2_51336A COG:K; EggNog:ENOG410PR74; InterPro:IPR019364; PFAM:PF10232; go_component: GO:0016592 - mediator complex [Evidence IEA]; go_function: GO:0003712 - transcription coregulator activity [Evidence IEA]; go_process: GO:0006357 - regulation of transcription by RNA polymerase II [Evidence IEA] AKAW2_51337A COG:S; EggNog:ENOG410Q1I9 AKAW2_51338S COG:S; EggNog:ENOG410Q1Y9 AKAW2_51339S CAZy:GH1; COG:G; EggNog:ENOG410PFTX; InterPro:IPR017853,IPR001360; PFAM:PF00232; SECRETED:SignalP(1-22); go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_51341A COG:S; EggNog:ENOG410PS7J; SECRETED:SignalP(1-36); TransMembrane:1 (n16-27c36/37o242-263i) AKAW2_51343A COG:S; EggNog:ENOG410Q1MX AKAW2_51344A COG:S; EggNog:ENOG410Q202; TransMembrane:1 (o27-48i) AKAW2_51345A COG:G; EggNog:ENOG410PGWP; InterPro:IPR018050,IPR016305,IPR014710,IPR001250, IPR011051; PFAM:PF01238; go_function: GO:0004476 - mannose-6-phosphate isomerase activity [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA]; go_process: GO:0009298 - GDP-mannose biosynthetic process [Evidence IEA] AKAW2_51346A COG:S; EggNog:ENOG410Q22B AKAW2_51347A COG:S; EggNog:ENOG410PQJB AKAW2_51348S COG:O; EggNog:ENOG410PKGX; InterPro:IPR027417 AKAW2_51349S COG:O; EggNog:ENOG410PKGX AKAW2_51350A COG:I; EggNog:ENOG410PI73; InterPro:IPR021771,IPR016035,IPR002641; PFAM:PF11815,PF01734; go_function: GO:0004806 - triglyceride lipase activity [Evidence IEA]; go_process: GO:0006629 - lipid metabolic process [Evidence IEA] AKAW2_51351A COG:S; EggNog:ENOG410PNSM; InterPro:IPR000073,IPR029058; PFAM:PF12697; TransMembrane:1 (o20-37i) AKAW2_51352A COG:S; EggNog:ENOG410PJK8; InterPro:IPR011990,IPR027417,IPR019734,IPR007111, IPR031350,IPR013026; PFAM:PF05729,PF13181,PF17109; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_51353A COG:S; EggNog:ENOG410PP1U AKAW2_51354S BUSCO:EOG09260NJW; COG:O; EggNog:ENOG410PGI2; InterPro:IPR002015,IPR016024,IPR011989,IPR016642, IPR040623,IPR004155,IPR035266; PFAM:PF13646,PF01851,PF18004; go_component: GO:0000502 - proteasome complex [Evidence IEA]; go_function: GO:0030234 - enzyme regulator activity [Evidence IEA]; go_process: GO:0042176 - regulation of protein catabolic process [Evidence IEA] AKAW2_51355S COG:I; EggNog:ENOG410PFI9; InterPro:IPR006091,IPR001199,IPR009075,IPR037069, IPR009100,IPR036400,IPR036250,IPR013786; PFAM:PF02770,PF00173,PF00441,PF02771,PF08028; go_function: GO:0016627 - oxidoreductase activity, acting on the CH-CH group of donors [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_51356S BUSCO:EOG09260NXC; COG:K; EggNog:ENOG410PFCB; InterPro:IPR017071,IPR005100,IPR039659,IPR041978, IPR022581,IPR041976,IPR041975,IPR008991,IPR041973, IPR005824,IPR024945,IPR041977,IPR039385,IPR036735, IPR006645,IPR014722; PFAM:PF03439,PF12815,PF11942; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA]; go_process: GO:0006357 - regulation of transcription by RNA polymerase II [Evidence IEA]; go_process: GO:0032784 - regulation of DNA-templated transcription, elongation [Evidence IEA] AKAW2_51357A BUSCO:EOG09264P4J; COG:A; EggNog:ENOG410PR9U; InterPro:IPR004206,IPR040343,IPR033469,IPR037009; PFAM:PF02940; go_function: GO:0004651 - polynucleotide 5'-phosphatase activity [Evidence IEA] AKAW2_51358A BUSCO:EOG09262J7K; COG:S; EggNog:ENOG410PFK8; InterPro:IPR036322,IPR015943,IPR019775,IPR001680, IPR017986; PFAM:PF00400; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_51359S COG:H; EggNog:ENOG410PNHE AKAW2_51360S COG:S; EggNog:ENOG410PN6B AKAW2_51361A COG:O; EggNog:ENOG410PIT8; InterPro:IPR015915; PFAM:PF13418,PF13415,PF13854; TransMembrane:1 (i612-630o); go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_51362A COG:O; EggNog:ENOG410PFVX; InterPro:IPR019479,IPR000866,IPR036249,IPR013766, IPR024706; PFAM:PF08534,PF10417,PF00578; go_function: GO:0016209 - antioxidant activity [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0051920 - peroxiredoxin activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_51363S COG:S; EggNog:ENOG410PN4B; InterPro:IPR000116,IPR002740,IPR017956,IPR015947; PFAM:PF02178,PF01878; go_component: GO:0000785 - chromatin [Evidence IEA]; go_component: GO:0005634 - nucleus [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_51364S COG:C; EggNog:ENOG410PJ9J; InterPro:IPR015590,IPR029510,IPR016161,IPR016162, IPR016163; PFAM:PF00171; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0016620 - oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_51365S COG:P,T; EggNog:ENOG410PIR3; InterPro:IPR011042,IPR005511,IPR013658; PFAM:PF08450 AKAW2_51367S COG:S; EggNog:ENOG410PRBS; InterPro:IPR004827; go_function: GO:0003700 - DNA-binding transcription factor activity [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_51368S COG:S; EggNog:ENOG410PJ9P; InterPro:IPR016274,IPR033379,IPR000560,IPR029033; PFAM:PF00328; TransMembrane:1 (i21-44o); go_function: GO:0016791 - phosphatase activity [Evidence IEA] AKAW2_51369A COG:S; EggNog:ENOG410PY7W AKAW2_51370S COG:O; EggNog:ENOG410PK8H; InterPro:IPR008814; SECRETED:SignalP(1-23); TransMembrane:3 (n7-18c23/24o190-218i230-250o256-277i); go_component: GO:0008250 - oligosaccharyltransferase complex [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_process: GO:0006487 - protein N-linked glycosylation [Evidence IEA] AKAW2_51371S COG:S; EggNog:ENOG410PRU3 AKAW2_51372A COG:Q; EggNog:ENOG410PHZV; InterPro:IPR002347,IPR036291,IPR020904; PFAM:PF00106,PF13561,PF08659; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_51373A COG:C; EggNog:ENOG410PHVT; InterPro:IPR023210,IPR036812; PFAM:PF00248 AKAW2_51374S COG:S; EggNog:ENOG410PP4G; InterPro:IPR006620,IPR005123; PFAM:PF13640; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0031418 - L-ascorbic acid binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_51375S COG:I; EggNog:ENOG410PFXA; InterPro:IPR016035,IPR002642; PFAM:PF01735; SECRETED:SignalP(1-24); TransMembrane:1 (n8-19c24/25o617-637i); go_function: GO:0004620 - phospholipase activity [Evidence IEA]; go_process: GO:0009395 - phospholipid catabolic process [Evidence IEA] AKAW2_51376S COG:S; EggNog:ENOG410PJW7; InterPro:IPR001357,IPR036420,IPR022047 AKAW2_51377A COG:S; EggNog:ENOG410PR49; InterPro:IPR044034,IPR038922; PFAM:PF19026 AKAW2_51378S COG:E; EggNog:ENOG410PIHP; InterPro:IPR002480,IPR013785; PFAM:PF01474; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0003849 - 3-deoxy-7-phosphoheptulonate synthase activity [Evidence IEA]; go_process: GO:0009073 - aromatic amino acid family biosynthetic process [Evidence IEA] AKAW2_51379A COG:G; EggNog:ENOG410QE1F; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:11 (o201-219i231-249o255-278i290-313o343-365i453-478o505- 527i539-557o563-590i602-626o638-657i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_51380A TransMembrane:2 (o56-76i83-100o) AKAW2_51381A COG:S; EggNog:ENOG410PTPW; InterPro:IPR024957,IPR025925; PFAM:PF06657,PF14197; go_function: GO:0008017 - microtubule binding [Evidence IEA] AKAW2_51382A COG:S; EggNog:ENOG410PN17; TransMembrane:1 (o51-73i) AKAW2_51383S COG:S; EggNog:ENOG410PP8S; InterPro:IPR002925,IPR029058; PFAM:PF01738; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_51384A COG:Q; EggNog:ENOG410PGKJ; InterPro:IPR017871,IPR027417,IPR003593,IPR039421, IPR011527,IPR003439,IPR036640; PFAM:PF00005,PF00664; TransMembrane:12 (i21-42o48-70i82-106o169-194i263-283o303-325i758-778o798- 820i871-892o898-918i978-1002o1014-1038i); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA]; go_function: GO:0042626 - ATPase-coupled transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_51385A BUSCO:EOG0926506Z; COG:S; EggNog:ENOG410PN7W; InterPro:IPR023139,IPR008476,IPR021148; PFAM:PF04669 AKAW2_51386A COG:S; EggNog:ENOG410PJDY; InterPro:IPR019318; PFAM:PF10165 AKAW2_51387S COG:S; EggNog:ENOG410PIGD; InterPro:IPR022031,IPR016024,IPR028566; PFAM:PF12231 AKAW2_51388S COG:O; EggNog:ENOG410PG37; InterPro:IPR001841,IPR013083; PFAM:PF17123,PF13923,PF00097,PF13639; TransMembrane:1 (o6-29i) AKAW2_51389A COG:G; EggNog:ENOG410PIY0; InterPro:IPR014718,IPR008183,IPR011013,IPR025532; PFAM:PF01263; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0016853 - isomerase activity [Evidence IEA]; go_function: GO:0030246 - carbohydrate binding [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_51390A COG:G; EggNog:ENOG410PVXA; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:13 (o58-77i128-146o152-175i187-208o214-236i256-277o289- 306i326-347o367-384i393-413o419-441i453-477o523-546i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_51391A COG:T; EggNog:ENOG410PF9W; InterPro:IPR000719,IPR011009,IPR008271; PFAM:PF07714,PF00069; TransMembrane:1 (o643-674i); go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_51392A COG:S; EggNog:ENOG410PFCP; InterPro:IPR024929,IPR012971,IPR030378,IPR027417, IPR006073,IPR023179; PFAM:PF08153; go_component: GO:0005730 - nucleolus [Evidence IEA]; go_function: GO:0005525 - GTP binding [Evidence IEA] AKAW2_51393S COG:S; EggNog:ENOG410PR6M AKAW2_51394A BUSCO:EOG092649XV; COG:K; EggNog:ENOG410PJHJ; InterPro:IPR001841,IPR004575,IPR017907,IPR015877, IPR013083; PFAM:PF06391,PF17121; go_component: GO:0005675 - transcription factor TFIIH holo complex [Evidence IEA]; go_function: GO:0061575 - cyclin-dependent protein serine/threonine kinase activator activity [Evidence IEA]; go_process: GO:0006289 - nucleotide-excision repair [Evidence IEA]; go_process: GO:0045737 - positive regulation of cyclin-dependent protein serine/threonine kinase activity [Evidence IEA] AKAW2_51395S COG:S; EggNog:ENOG410PM3B; InterPro:IPR024325,IPR039553; PFAM:PF13758 AKAW2_51396S COG:S; EggNog:ENOG410PQ3Z; InterPro:IPR018620; PFAM:PF09792 AKAW2_51397A COG:S; EggNog:ENOG410Q2K8 AKAW2_51398A COG:A; EggNog:ENOG410PIUX; InterPro:IPR036322,IPR027417,IPR007111,IPR015943, IPR001680,IPR019775,IPR020472,IPR031359,IPR017986; PFAM:PF05729,PF00400,PF17100; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_51399S COG:Q; EggNog:ENOG410PW7K; InterPro:IPR036291,IPR002347; PFAM:PF00106,PF13561; TransMembrane:1 (o107-127i); go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_51400S COG:I; EggNog:ENOG410PMFW; InterPro:IPR036938,IPR043216,IPR000326; PFAM:PF01569; TransMembrane:6 (i20-40o69-90i123-144o194-212i224-243o255-273i); go_function: GO:0008195 - phosphatidate phosphatase activity [Evidence IEA]; go_process: GO:0006644 - phospholipid metabolic process [Evidence IEA] AKAW2_51401S COG:S; EggNog:ENOG410PQBV; TransMembrane:5 (i12-33o39-58i70-90o102-120i141-162o) AKAW2_51402S COG:H; EggNog:ENOG410PHRF; InterPro:IPR015424,IPR005302,IPR005303,IPR028886, IPR000192,IPR015421,IPR015422; PFAM:PF03476,PF00266,PF03473; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0008265 - Mo-molybdopterin cofactor sulfurase activity [Evidence IEA]; go_function: GO:0030151 - molybdenum ion binding [Evidence IEA]; go_function: GO:0030170 - pyridoxal phosphate binding [Evidence IEA]; go_process: GO:0006777 - Mo-molybdopterin cofactor biosynthetic process [Evidence IEA] AKAW2_51403A COG:S; EggNog:ENOG410PQ04; InterPro:IPR037507,IPR040922; PFAM:PF18126; go_component: GO:0005762 - mitochondrial large ribosomal subunit [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA] AKAW2_51404S COG:A; EggNog:ENOG410PIX7; InterPro:IPR003107,IPR011990; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0006396 - RNA processing [Evidence IEA] AKAW2_51405S BUSCO:EOG09261JWS; COG:A; EggNog:ENOG410PFDF; InterPro:IPR027417,IPR001650,IPR014014,IPR014001, IPR011545,IPR000629; PFAM:PF00270,PF00271; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0004386 - helicase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA] AKAW2_51406A COG:E,O; EggNog:ENOG410PGKM; InterPro:IPR014782,IPR042097,IPR024571,IPR034016, IPR001930; MEROPS:MER0001010; PFAM:PF17900,PF01433,PF11838; go_function: GO:0008237 - metallopeptidase activity [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006508 - proteolysis [Evidence IEA] AKAW2_51407A COG:E; EggNog:ENOG410PFCI; InterPro:IPR002293; PFAM:PF00324,PF13520; TransMembrane:10 (i42-60o80-101i113-134o154-177i189-212o241-265i286- 307o319-340i352-370o390-414i); go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_51408A COG:O,T,U; EggNog:ENOG410PHHV; InterPro:IPR017441,IPR008271,IPR022708,IPR000719, IPR011009; PFAM:PF12063,PF07714,PF00069; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0004674 - protein serine/threonine kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_51409A TransMembrane:3 (o16-33i40-59o65-87i) AKAW2_51410A BUSCO:EOG09260LVD; COG:I; EggNog:ENOG410PIB5; InterPro:IPR032974; TransMembrane:11 (i156-174o186-203i328-351o363-380i529-547o562-585i624- 644o664-693i722-742o762-781i802-821o) AKAW2_51411A COG:J; EggNog:ENOG410PGIT; InterPro:IPR006175,IPR002761,IPR035959,IPR030662; PFAM:PF01042,PF01902 AKAW2_51412A COG:K; EggNog:ENOG410PM3K; InterPro:IPR036236,IPR013087; PFAM:PF00096,PF12874 AKAW2_51413A COG:O; EggNog:ENOG410PPRZ; InterPro:IPR017937,IPR008979,IPR036249,IPR010400, IPR013766,IPR037047; PFAM:PF06201 AKAW2_51414A COG:O; EggNog:ENOG410PQVT; InterPro:IPR001623,IPR036869,IPR036671,IPR007872; PFAM:PF00226,PF05207 AKAW2_51415A CAZy:AA2; COG:C; EggNog:ENOG410PH8T; InterPro:IPR002016,IPR010255,IPR019794,IPR019793, IPR002207; PFAM:PF00141; TransMembrane:1 (o58-76i); go_function: GO:0004601 - peroxidase activity [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0006979 - response to oxidative stress [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_51416A COG:S; EggNog:ENOG410PSHR; TransMembrane:7 (o6-27i39-62o68-94i106-129o149-167i179-203o215-236i) AKAW2_51417S COG:S; EggNog:ENOG410PWIG; InterPro:IPR036864,IPR021858,IPR001138; PFAM:PF00172; TransMembrane:1 (o458-478i); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_51418S COG:T; EggNog:ENOG410PGVY; InterPro:IPR001164,IPR009060,IPR037278,IPR038508; PFAM:PF01412; go_function: GO:0005096 - GTPase activator activity [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_51419A BUSCO:EOG09260UJK; CAZy:GT22; COG:G; EggNog:ENOG410PJAY; InterPro:IPR039521,IPR005599; PFAM:PF03901; TransMembrane:8 (i87-106o284-308i320-338o350-367i379-398o413-431i438- 458o478-505i); go_function: GO:0000026 - alpha-1,2-mannosyltransferase activity [Evidence IEA]; go_function: GO:0004376 - glycolipid mannosyltransferase activity [Evidence IEA]; go_function: GO:0016757 - transferase activity, transferring glycosyl groups [Evidence IEA]; go_process: GO:0006506 - GPI anchor biosynthetic process [Evidence IEA] AKAW2_51420S COG:E; EggNog:ENOG410PHVB; InterPro:IPR005814,IPR010164,IPR015424,IPR015421, IPR015422; PFAM:PF00202; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0004587 - ornithine-oxo-acid transaminase activity [Evidence IEA]; go_function: GO:0008483 - transaminase activity [Evidence IEA]; go_function: GO:0030170 - pyridoxal phosphate binding [Evidence IEA] AKAW2_51421A COG:G; EggNog:ENOG410PH6P; InterPro:IPR015377,IPR036462,IPR036663,IPR011234, IPR005959; PFAM:PF09298,PF01557; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0004334 - fumarylacetoacetase activity [Evidence IEA]; go_process: GO:0009072 - aromatic amino acid family metabolic process [Evidence IEA] AKAW2_51423S COG:G; EggNog:ENOG410QDX4; InterPro:IPR036259; SECRETED:SignalP(1-21); TransMembrane:4 (i87-106o112-138i150-171o177-201i) AKAW2_51424A COG:Q; EggNog:ENOG410PW5Q; InterPro:IPR002347,IPR036291,IPR020904; PFAM:PF00106,PF13561,PF08659,PF01370; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_51426S COG:H; EggNog:ENOG410PGQ2; InterPro:IPR029063,IPR013216; PFAM:PF01209,PF13649,PF13489,PF08241,PF08242, PF02353,PF13847; go_function: GO:0008168 - methyltransferase activity [Evidence IEA] AKAW2_51427S COG:S; EggNog:ENOG410Q1N2; antiSMASH:Cluster_5.15 AKAW2_51428S COG:P; EggNog:ENOG410PM5S; InterPro:IPR005829,IPR005828,IPR020846,IPR036259; PFAM:PF07690; SMCOG1169:sugar transport protein; TransMembrane:12 (i38-59o79-100i112-131o143-161i182-201o221-240i337- 355o392-418i430-449o455-478i490-515o527-548i); antiSMASH:Cluster_5.15; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_51429S COG:Q; EggNog:ENOG410PJH7; InterPro:IPR036188,IPR032710; PFAM:PF07992,PF13738,PF13450; SMCOG1092:hypothetical protein; antiSMASH:Cluster_5.15 AKAW2_51430A COG:S; EggNog:ENOG410Q2VI; antiSMASH:Cluster_5.15 AKAW2_51431S COG:S; EggNog:ENOG410PTAW; PFAM:PF08592; TransMembrane:4 (o16-41i69-85o105-123i158-180o); antiSMASH:Cluster_5.15 AKAW2_51432A COG:I; EggNog:ENOG410Q1IU; InterPro:IPR042099,IPR000873,IPR025110; PFAM:PF00501,PF13193; SMCOG1002:AMP-dependent synthetase and ligase; antiSMASH:Cluster_5.15 AKAW2_51433A COG:I; EggNog:ENOG410PIJA; InterPro:IPR016036,IPR016035,IPR016039,IPR018201, IPR042104,IPR014030,IPR014031,IPR013968,IPR001227, IPR032821,IPR006162,IPR014043,IPR020806,IPR020807, IPR020841,IPR009081,IPR029063,IPR036736,IPR036291, IPR013217; PFAM:PF16197,PF00109,PF00550,PF13489,PF13649, PF01209,PF02801,PF00698,PF13847,PF08659,PF14765,PF00106, PF08242,PF08241; SMCOG1022:Beta-ketoacyl synthase; antiSMASH:Cluster_5.15; go_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein] synthase activity [Evidence IEA]; go_function: GO:0016740 - transferase activity [Evidence IEA]; go_function: GO:0016746 - transferase activity, transferring acyl groups [Evidence IEA]; go_function: GO:0031177 - phosphopantetheine binding [Evidence IEA]; go_process: GO:0006633 - fatty acid biosynthetic process [Evidence IEA] AKAW2_51434S COG:Q; EggNog:ENOG410PQMA; InterPro:IPR029063; PFAM:PF13489; antiSMASH:Cluster_5.15 AKAW2_51435S COG:S; EggNog:ENOG410PSXJ; InterPro:IPR029058,IPR001031; PFAM:PF12697,PF00975; antiSMASH:Cluster_5.15; go_function: GO:0016788 - hydrolase activity, acting on ester bonds [Evidence IEA]; go_process: GO:0009058 - biosynthetic process [Evidence IEA] AKAW2_51436S COG:Q; EggNog:ENOG410PHE8; InterPro:IPR022313,IPR001106,IPR023144,IPR024083, IPR005922,IPR008948; PFAM:PF00221; antiSMASH:Cluster_5.15; go_component: GO:0005737 - cytoplasm [Evidence IEA]; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0016841 - ammonia-lyase activity [Evidence IEA]; go_process: GO:0006559 - L-phenylalanine catabolic process [Evidence IEA] AKAW2_51437A COG:I; EggNog:ENOG410Q2PG; InterPro:IPR000873,IPR020845,IPR009081,IPR036291, IPR036736,IPR010080,IPR013120,IPR042099,IPR010071, IPR025110; PFAM:PF00501,PF01073,PF13193,PF00550,PF01370, PF07993; SMCOG1002:AMP-dependent synthetase and ligase; antiSMASH:Cluster_5.15 AKAW2_51438S COG:S; EggNog:ENOG410PU3U; InterPro:IPR000868,IPR036380; PFAM:PF00857; antiSMASH:Cluster_5.15 AKAW2_51439A COG:S; EggNog:ENOG410PQ9U; InterPro:IPR002110,IPR036770,IPR020683; PFAM:PF13857,PF12796,PF00023,PF13637,PF13606; antiSMASH:Cluster_5.15; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_51440S COG:O; EggNog:ENOG410Q2YQ; InterPro:IPR011118,IPR029058; PFAM:PF07519; SECRETED:SignalP(1-20); antiSMASH:Cluster_5.15 AKAW2_51441A COG:C; EggNog:ENOG410PMMX; InterPro:IPR016166,IPR006094,IPR036318; PFAM:PF01565; SMCOG1138:FAD linked oxidase domain protein; antiSMASH:Cluster_5.15; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_function: GO:0071949 - FAD binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_51442S COG:S; EggNog:ENOG410PSDX; SECRETED:SignalP(1-21); antiSMASH:Cluster_5.16 AKAW2_51443S COG:S; EggNog:ENOG410PXI2; InterPro:IPR000182,IPR016181; PFAM:PF00583; antiSMASH:Cluster_5.16; go_function: GO:0008080 - N-acetyltransferase activity [Evidence IEA] AKAW2_51444S InterPro:IPR027417,IPR000330,IPR038718; antiSMASH:Cluster_5.16; go_function: GO:0005524 - ATP binding [Evidence IEA] AKAW2_51446A COG:C; EggNog:ENOG410PMCP; InterPro:IPR013154,IPR013149,IPR036291,IPR011032, IPR020843; PFAM:PF00107,PF08240; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_51445S COG:K; EggNog:ENOG410PJPW; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_51447S COG:S; EggNog:ENOG410PM38; InterPro:IPR007657; PFAM:PF04577; go_function: GO:0016757 - transferase activity, transferring glycosyl groups [Evidence IEA] AKAW2_51448A COG:S; EggNog:ENOG410PTQE; InterPro:IPR004827; PFAM:PF00170,PF07716; go_function: GO:0003700 - DNA-binding transcription factor activity [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_51449S CAZy:GH75; COG:G; EggNog:ENOG410PPXK; InterPro:IPR009939; PFAM:PF07335; SECRETED:SignalP(1-20); go_function: GO:0016977 - chitosanase activity [Evidence IEA] AKAW2_51450A COG:S; EggNog:ENOG410PK83; InterPro:IPR032675 AKAW2_51452S COG:S; EggNog:ENOG410PU9G; InterPro:IPR002110,IPR036770,IPR020683,IPR010730; PFAM:PF13857,PF06985,PF12796,PF00023,PF13637, PF13606; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_51453A COG:S; EggNog:ENOG410PW0A; InterPro:IPR001810; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_51454A CAZy:GT69; COG:S; EggNog:ENOG410PGW7; InterPro:IPR021047; PFAM:PF11735; TransMembrane:1 (i12-32o) AKAW2_51455A COG:H; EggNog:ENOG410PK7M; InterPro:IPR033749,IPR008949,IPR000092; PFAM:PF19086,PF00348; go_process: GO:0008299 - isoprenoid biosynthetic process [Evidence IEA] AKAW2_51456S CAZy:GH18; COG:G; EggNog:ENOG410PH2N; InterPro:IPR018392,IPR011583,IPR029070,IPR001223, IPR017853,IPR014248,IPR001579,IPR036779; PFAM:PF00704,PF01476; go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_function: GO:0008061 - chitin binding [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_51457A COG:C,H; EggNog:ENOG410PUA1; InterPro:IPR036188,IPR002938,IPR036249,IPR038220, IPR012941; PFAM:PF07976,PF01494; go_function: GO:0071949 - FAD binding [Evidence IEA] AKAW2_51458A COG:K; EggNog:ENOG410PVKB; InterPro:IPR036864,IPR021858,IPR001138; PFAM:PF00172,PF11951; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_51459S COG:Q; EggNog:ENOG410PNPY; InterPro:IPR002935,IPR029063; PFAM:PF13578,PF01596; go_function: GO:0008171 - O-methyltransferase activity [Evidence IEA] AKAW2_51460A COG:K; EggNog:ENOG410PM5K; InterPro:IPR012349,IPR007396; PFAM:PF04299 AKAW2_51461S COG:E; EggNog:ENOG410PFYU; InterPro:IPR000277,IPR015424,IPR015421,IPR015422; PFAM:PF01053; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0030170 - pyridoxal phosphate binding [Evidence IEA]; go_process: GO:0019346 - transsulfuration [Evidence IEA] AKAW2_51462S COG:S; EggNog:ENOG410PJ8E AKAW2_51463S COG:S; EggNog:ENOG410PHUE AKAW2_51464S BUSCO:EOG09260AZA; COG:G; EggNog:ENOG410PFJN; InterPro:IPR005475,IPR011603,IPR032106,IPR029061, IPR001017,IPR031717,IPR042179; PFAM:PF02779,PF00676,PF16078,PF16870; go_function: GO:0004591 - oxoglutarate dehydrogenase (succinyl-transferring) activity [Evidence IEA]; go_function: GO:0016624 - oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor [Evidence IEA]; go_function: GO:0030976 - thiamine pyrophosphate binding [Evidence IEA]; go_process: GO:0006099 - tricarboxylic acid cycle [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_51465S COG:S; EggNog:ENOG410PXC4; InterPro:IPR011009,IPR002575; PFAM:PF01636 AKAW2_51466S CAZy:GT69; COG:S; EggNog:ENOG410PHXT; InterPro:IPR021047 AKAW2_51467S COG:S; EggNog:ENOG410PSM4; TransMembrane:5 (i175-198o218-239i251-274o286-303i746-768o) AKAW2_51468A BUSCO:EOG09264W1U; COG:S; EggNog:ENOG410Q12X; TransMembrane:3 (o15-31i52-76o88-111i) AKAW2_51469A BUSCO:EOG0926315C; COG:K; EggNog:ENOG410PKJY; InterPro:IPR011993,IPR027079,IPR013876,IPR005607; PFAM:PF03909,PF08567; go_component: GO:0000439 - transcription factor TFIIH core complex [Evidence IEA]; go_process: GO:0006289 - nucleotide-excision repair [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA] AKAW2_51470S COG:S; EggNog:ENOG410PSSX AKAW2_51471S TransMembrane:2 (o20-37i44-62o) AKAW2_51472S BUSCO:EOG09264O2D; COG:L; EggNog:ENOG410PNMZ; InterPro:IPR038437,IPR021151,IPR010492,IPR036224; PFAM:PF05916 AKAW2_51473S COG:S; EggNog:ENOG410PP8G; InterPro:IPR012943; PFAM:PF07989; go_component: GO:0005815 - microtubule organizing center [Evidence IEA] AKAW2_51474A COG:S; EggNog:ENOG410PJ10 AKAW2_51475A COG:P; EggNog:ENOG410PUNZ; InterPro:IPR036314,IPR019833,IPR019832,IPR019831, IPR036324,IPR001189; PFAM:PF02777,PF00081; go_function: GO:0004784 - superoxide dismutase activity [Evidence IEA]; go_function: GO:0046872 - metal ion binding [Evidence IEA]; go_process: GO:0006801 - superoxide metabolic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_51476S COG:A; EggNog:ENOG410PFU8; InterPro:IPR022783,IPR000467; PFAM:PF07842,PF12656,PF01585; go_function: GO:0003676 - nucleic acid binding [Evidence IEA] AKAW2_51477A COG:G; EggNog:ENOG410PFNN; InterPro:IPR018485,IPR018484,IPR018483,IPR005999, IPR043129; PFAM:PF00370,PF02782; go_function: GO:0004370 - glycerol kinase activity [Evidence IEA]; go_function: GO:0016773 - phosphotransferase activity, alcohol group as acceptor [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA]; go_process: GO:0006072 - glycerol-3-phosphate metabolic process [Evidence IEA] AKAW2_51478A COG:S; EggNog:ENOG410PNM5; InterPro:IPR021836; PFAM:PF11911; TransMembrane:3 (i158-178o198-223i235-258o) AKAW2_51479S BUSCO:EOG09260075; COG:U; EggNog:ENOG410PH81; InterPro:IPR031646,IPR031645,IPR031642,IPR017148, IPR026854,IPR026847,IPR009543; PFAM:PF06650,PF16909,PF16908,PF16910,PF12624 AKAW2_51480A TransMembrane:1 (o14-35i) AKAW2_51481A COG:O; EggNog:ENOG410PFTB; InterPro:IPR000642,IPR041569,IPR003959,IPR027417, IPR003593,IPR003960,IPR037219,IPR005936; MEROPS:MER0002197; PFAM:PF00004,PF01434,PF17862,PF07728; TransMembrane:1 (i292-311o); go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0004176 - ATP-dependent peptidase activity [Evidence IEA]; go_function: GO:0004222 - metalloendopeptidase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA]; go_process: GO:0006508 - proteolysis [Evidence IEA] AKAW2_51482S COG:S; EggNog:ENOG410PNSY AKAW2_51483S COG:M; EggNog:ENOG410PFAH; InterPro:IPR029044,IPR005835,IPR018357,IPR001451; PFAM:PF00483,PF12804,PF00132; go_function: GO:0016740 - transferase activity [Evidence IEA]; go_function: GO:0016779 - nucleotidyltransferase activity [Evidence IEA]; go_process: GO:0009058 - biosynthetic process [Evidence IEA] AKAW2_51484A BUSCO:EOG09262SR7; COG:I; EggNog:ENOG410PJ4U; InterPro:IPR036291,IPR002347; PFAM:PF00106; TransMembrane:1 (o285-304i); go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_51486S COG:K; EggNog:ENOG410Q2F0; InterPro:IPR036236,IPR013087; PFAM:PF00096 AKAW2_51488S SECRETED:SignalP(1-23) AKAW2_51487A COG:T; EggNog:ENOG410PGF3; InterPro:IPR017850,IPR037675,IPR002591,IPR039524; TransMembrane:15 (o14-34i444-462o474-494i506-527o533-551i563-582o588- 606i626-644o656-676i697-718o730-755i776-793o813-836i848- 871o883-904i); go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0016772 - transferase activity, transferring phosphorus-containing groups [Evidence IEA]; go_function: GO:0051377 - mannose-ethanolamine phosphotransferase activity [Evidence IEA]; go_process: GO:0006506 - GPI anchor biosynthetic process [Evidence IEA] AKAW2_51489A COG:O; EggNog:ENOG410PGRE; InterPro:IPR009737,IPR036249; PFAM:PF06999 AKAW2_51490A COG:S; EggNog:ENOG410PIBJ; InterPro:IPR038869; TransMembrane:1 (n8-27c32/33o42-63i) AKAW2_51491A COG:E; EggNog:ENOG410PGKB; InterPro:IPR004839,IPR015424,IPR015421; PFAM:PF00155; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0030170 - pyridoxal phosphate binding [Evidence IEA]; go_process: GO:0009058 - biosynthetic process [Evidence IEA] AKAW2_51493A COG:T; EggNog:ENOG410Q554; InterPro:IPR000219,IPR033511,IPR010481,IPR035899, IPR011993,IPR001849,IPR036872,IPR000270; PFAM:PF06395,PF00564,PF15411,PF00621; go_function: GO:0005085 - guanyl-nucleotide exchange factor activity [Evidence IEA]; go_function: GO:0005089 - Rho guanyl-nucleotide exchange factor activity [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_51494S COG:S; EggNog:ENOG410QE9X; InterPro:IPR001810,IPR036322,IPR015943,IPR001680, IPR036047,IPR019775,IPR020472,IPR017986; PFAM:PF00646,PF00400,PF12937; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_51495A COG:S; EggNog:ENOG410PZQ7 AKAW2_51496S COG:U; EggNog:ENOG410PJ5A; InterPro:IPR011701,IPR036259; PFAM:PF07690; TransMembrane:10 (i38-56o76-98i131-153o201-219i251-270o290-309i316-337o343- 368i380-399o419-439i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_51497A COG:C; EggNog:ENOG410PRZT; InterPro:IPR003422,IPR023184,IPR036811; PFAM:PF02320; go_function: GO:0008121 - ubiquinol-cytochrome-c reductase activity [Evidence IEA]; go_process: GO:0006122 - mitochondrial electron transport, ubiquinol to cytochrome c [Evidence IEA] AKAW2_51498A COG:T; EggNog:ENOG410PNWH; InterPro:IPR011993 AKAW2_51499S COG:I; EggNog:ENOG410PG3D; InterPro:IPR018520,IPR001441,IPR036424; PFAM:PF01255; go_function: GO:0016765 - transferase activity, transferring alkyl or aryl (other than methyl) groups [Evidence IEA] AKAW2_51500S COG:E; EggNog:ENOG410Q4IA; InterPro:IPR032095,IPR036291,IPR005097; PFAM:PF03435,PF01488,PF16653; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_51501A COG:O; EggNog:ENOG410PHXM; InterPro:IPR013538,IPR036338,IPR023393,IPR039981, IPR015310; PFAM:PF08327,PF09229; TransMembrane:1 (o325-345i); go_function: GO:0001671 - ATPase activator activity [Evidence IEA]; go_function: GO:0051087 - chaperone binding [Evidence IEA]; go_function: GO:0051879 - Hsp90 protein binding [Evidence IEA] AKAW2_51502A COG:S; EggNog:ENOG410PKGC AKAW2_51503A TransMembrane:1 (o35-56i) AKAW2_51504S BUSCO:EOG092632WW; COG:G; EggNog:ENOG410PGFG; InterPro:IPR000146,IPR028343,IPR044015,IPR033391, IPR020548; PFAM:PF18913,PF00316; go_function: GO:0016791 - phosphatase activity [Evidence IEA]; go_function: GO:0042132 - fructose 1,6-bisphosphate 1-phosphatase activity [Evidence IEA]; go_function: GO:0042578 - phosphoric ester hydrolase activity [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_51506A COG:C; EggNog:ENOG410PGDY; InterPro:IPR002490,IPR026028; PFAM:PF01496; TransMembrane:7 (o425-450i462-482o547-567i579-602o614-632i644-661o785- 806i); go_component: GO:0000220 - vacuolar proton-transporting V-type ATPase, V0 domain [Evidence IEA]; go_component: GO:0033179 - proton-transporting V-type ATPase, V0 domain [Evidence IEA]; go_function: GO:0015078 - proton transmembrane transporter activity [Evidence IEA]; go_process: GO:1902600 - proton transmembrane transport [Evidence IEA] AKAW2_51507A COG:O; EggNog:ENOG410PFXY; InterPro:IPR016024,IPR032372,IPR021843,IPR032430, IPR035309; PFAM:PF16547,PF11919,PF16507; go_function: GO:0016504 - peptidase activator activity [Evidence IEA]; go_function: GO:0070577 - lysine-acetylated histone binding [Evidence IEA]; go_function: GO:0070628 - proteasome binding [Evidence IEA] AKAW2_51508A BUSCO:EOG09262GLP; CAZy:GT76; COG:G; EggNog:ENOG410PH12; InterPro:IPR007315; PFAM:PF04188; TransMembrane:11 (i21-41o132-155i167-187o193-212i224-250o270-288i328- 349o355-373i385-406o418-434i446-466o); antiSMASH:Cluster_5.17; go_function: GO:0000009 - alpha-1,6-mannosyltransferase activity [Evidence IEA]; go_function: GO:0004376 - glycolipid mannosyltransferase activity [Evidence IEA]; go_process: GO:0006506 - GPI anchor biosynthetic process [Evidence IEA] AKAW2_51509S COG:S; EggNog:ENOG410PR4E; antiSMASH:Cluster_5.17 AKAW2_51510A COG:C; EggNog:ENOG410PFM7; InterPro:IPR023210,IPR036812; PFAM:PF00248; SMCOG1039:aldo/keto reductase family oxidoreductase; antiSMASH:Cluster_5.17 AKAW2_51511S COG:S; EggNog:ENOG410Q06X; antiSMASH:Cluster_5.17 AKAW2_51512A BUSCO:EOG092603D0; COG:Q; EggNog:ENOG410PIYP; InterPro:IPR000873,IPR020845,IPR009081,IPR036291, IPR036736,IPR010080,IPR014397,IPR020806,IPR013120, IPR042099,IPR010071,IPR001242; PFAM:PF00501,PF01073,PF00668,PF00550,PF01370, PF07993; SMCOG1002:AMP-dependent synthetase and ligase; antiSMASH:Cluster_5.17; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0004043 - L-aminoadipate-semialdehyde dehydrogenase activity [Evidence IEA]; go_function: GO:0031177 - phosphopantetheine binding [Evidence IEA]; go_process: GO:0009085 - lysine biosynthetic process [Evidence IEA] AKAW2_51513S COG:S; EggNog:ENOG410PI6S; SECRETED:SignalP(1-24); antiSMASH:Cluster_5.17 AKAW2_51514S COG:F; EggNog:ENOG410PHQC; InterPro:IPR036683,IPR008274,IPR005107,IPR036318, IPR036856,IPR036884,IPR001041,IPR006058,IPR002888, IPR000674,IPR016208,IPR002346,IPR016166,IPR037165, IPR036010; PFAM:PF02738,PF00111,PF00941,PF03450,PF01799, PF01315; SMCOG1293:aldehyde oxidase and xanthine dehydrogenase; antiSMASH:Cluster_5.17; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0009055 - electron transfer activity [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0046872 - metal ion binding [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_function: GO:0051536 - iron-sulfur cluster binding [Evidence IEA]; go_function: GO:0051537 - 2 iron, 2 sulfur cluster binding [Evidence IEA]; go_function: GO:0071949 - FAD binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_51515A BUSCO:EOG09261VUC; COG:U; EggNog:ENOG410PJR3; InterPro:IPR026777,IPR043473; TransMembrane:4 (i51-73o321-339i393-418o599-625i); antiSMASH:Cluster_5.17; go_component: GO:0043332 - mating projection tip [Evidence IEA]; go_process: GO:0032220 - plasma membrane fusion involved in cytogamy [Evidence IEA] AKAW2_51516S COG:S; EggNog:ENOG410Q2HA; antiSMASH:Cluster_5.17 AKAW2_51517A BUSCO:EOG09262DKA; COG:E; EggNog:ENOG410PVV7; InterPro:IPR004839,IPR015424,IPR015421,IPR015422; PFAM:PF00155; SMCOG1019:aminotransferase; antiSMASH:Cluster_5.17; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0030170 - pyridoxal phosphate binding [Evidence IEA]; go_process: GO:0009058 - biosynthetic process [Evidence IEA] AKAW2_51518S BUSCO:EOG09261W2O; COG:L; EggNog:ENOG410PFT5; InterPro:IPR003959,IPR027417,IPR003593,IPR021886, IPR006642,IPR032423,IPR008921; PFAM:PF16193,PF00004,PF05496,PF12002,PF07726, PF07728; antiSMASH:Cluster_5.17; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA]; go_process: GO:0006260 - DNA replication [Evidence IEA]; go_process: GO:0006281 - DNA repair [Evidence IEA] AKAW2_51519S COG:D,Z; EggNog:ENOG410PR43; InterPro:IPR018247,IPR002048,IPR011992; PFAM:PF13833,PF13499; go_function: GO:0005509 - calcium ion binding [Evidence IEA] AKAW2_51520A COG:O; EggNog:ENOG410PHCT; InterPro:IPR041645,IPR034028,IPR001762,IPR024079, IPR001590,IPR006586,IPR036436; MEROPS:MER0182135; PFAM:PF13688,PF13574,PF13582,PF13583,PF00200, PF17771; SECRETED:SignalP(1-24); TransMembrane:1 (n8-19c24/25o700-721i); go_function: GO:0004222 - metalloendopeptidase activity [Evidence IEA]; go_function: GO:0008237 - metallopeptidase activity [Evidence IEA]; go_process: GO:0006508 - proteolysis [Evidence IEA] AKAW2_51521A COG:L; EggNog:ENOG410PKJB; InterPro:IPR001126,IPR043128,IPR017961,IPR043502; PFAM:PF00817,PF11799; go_function: GO:0003684 - damaged DNA binding [Evidence IEA]; go_process: GO:0006281 - DNA repair [Evidence IEA] AKAW2_51522S COG:S; EggNog:ENOG410PX7E; antiSMASH:Cluster_5.18 AKAW2_51523A COG:S; EggNog:ENOG410PHJ1; InterPro:IPR013216,IPR029063; PFAM:PF13649,PF08241; antiSMASH:Cluster_5.18; go_function: GO:0008168 - methyltransferase activity [Evidence IEA] AKAW2_51524S COG:Q; EggNog:ENOG410PPBW; InterPro:IPR037455,IPR007310; antiSMASH:Cluster_5.18; go_process: GO:0019290 - siderophore biosynthetic process [Evidence IEA] AKAW2_51525S COG:S; EggNog:ENOG410PRQI; InterPro:IPR007219; antiSMASH:Cluster_5.18; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA] AKAW2_51526A COG:E; EggNog:ENOG410PJIE; InterPro:IPR036526,IPR044149,IPR000132,IPR003010; PFAM:PF00795; SMCOG1294:Nitrilase/cyanide hydratase and apolipoprotein; antiSMASH:Cluster_5.18; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_process: GO:0006807 - nitrogen compound metabolic process [Evidence IEA] AKAW2_51527A COG:G; EggNog:ENOG410PNPH; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i25-53o59-80i92-109o121-142i154-175o181-201i263-284o304- 324i345-364o370-396i408-427o439-460i); antiSMASH:Cluster_5.18; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_51528S CAZy:GH3; COG:G; EggNog:ENOG410PVVB; InterPro:IPR017853,IPR036962,IPR002772,IPR036881, IPR026891,IPR013783,IPR001764; PFAM:PF14310,PF00933,PF01915; SECRETED:SignalP(1-17); go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_51529A COG:S; EggNog:ENOG410PIKS; InterPro:IPR037767,IPR037765,IPR035892,IPR000008, IPR031468; PFAM:PF00168; TransMembrane:3 (i180-198o204-220i375-393o); go_function: GO:0008289 - lipid binding [Evidence IEA]; go_process: GO:0061817 - endoplasmic reticulum-plasma membrane tethering [Evidence IEA] AKAW2_51530S COG:S; EggNog:ENOG410PIY2; InterPro:IPR011009 AKAW2_51531S COG:S; EggNog:ENOG410PIY2; InterPro:IPR011009 AKAW2_51532S COG:S; EggNog:ENOG410PRMV; InterPro:IPR028143; PFAM:PF08690; TransMembrane:2 (i210-233o253-270i) AKAW2_51533S COG:I; EggNog:ENOG410PGXP; InterPro:IPR000873,IPR020845,IPR032387,IPR011904, IPR042099,IPR025110; PFAM:PF00501,PF16177,PF13193; go_function: GO:0003987 - acetate-CoA ligase activity [Evidence IEA]; go_function: GO:0016208 - AMP binding [Evidence IEA]; go_process: GO:0019427 - acetyl-CoA biosynthetic process from acetate [Evidence IEA] AKAW2_51534S COG:U,Y; EggNog:ENOG410Q4JQ; InterPro:IPR025574,IPR037665,IPR037637,IPR021967, IPR007230,IPR036903; MEROPS:MER0020214; PFAM:PF04096,PF12110,PF13634; go_component: GO:0005643 - nuclear pore [Evidence IEA]; go_function: GO:0017056 - structural constituent of nuclear pore [Evidence IEA]; go_process: GO:0006913 - nucleocytoplasmic transport [Evidence IEA] AKAW2_51535A COG:C; EggNog:ENOG410PK2H; InterPro:IPR019554,IPR019575,IPR001949,IPR011537, IPR037207,IPR037225,IPR011538; PFAM:PF10589,PF01512,PF10531; go_function: GO:0008137 - NADH dehydrogenase (ubiquinone) activity [Evidence IEA]; go_function: GO:0010181 - FMN binding [Evidence IEA]; go_function: GO:0016651 - oxidoreductase activity, acting on NAD(P)H [Evidence IEA]; go_function: GO:0051287 - NAD binding [Evidence IEA]; go_function: GO:0051539 - 4 iron, 4 sulfur cluster binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_51536A COG:S; EggNog:ENOG410QE4T; InterPro:IPR001214; PFAM:PF00856; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_51537A COG:D; EggNog:ENOG410PH0E; InterPro:IPR007587; PFAM:PF04499; go_function: GO:0019903 - protein phosphatase binding [Evidence IEA]; go_process: GO:0043666 - regulation of phosphoprotein phosphatase activity [Evidence IEA] AKAW2_51538S BUSCO:EOG09264OXC; COG:U; EggNog:ENOG410PKYZ; InterPro:IPR005024; PFAM:PF03357; go_process: GO:0007034 - vacuolar transport [Evidence IEA] AKAW2_51539A COG:P; EggNog:ENOG410PIE8; InterPro:IPR001046; PFAM:PF01566; TransMembrane:11 (i121-141o153-174i195-217o229-249i261-283o306-325i377- 402o422-447i468-486o498-517i546-572o); go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0046873 - metal ion transmembrane transporter activity [Evidence IEA]; go_process: GO:0030001 - metal ion transport [Evidence IEA] AKAW2_51540S COG:S; EggNog:ENOG410PJ46; InterPro:IPR016024,IPR010473; PFAM:PF06371; go_function: GO:0003779 - actin binding [Evidence IEA]; go_function: GO:0017048 - Rho GTPase binding [Evidence IEA]; go_process: GO:0030036 - actin cytoskeleton organization [Evidence IEA] AKAW2_51541A COG:S; EggNog:ENOG410PTYK; TransMembrane:1 (i126-143o) AKAW2_51542S COG:I; EggNog:ENOG410PFKZ; InterPro:IPR016039,IPR020613,IPR020610,IPR020617, IPR020616,IPR020615,IPR002155; PFAM:PF00108,PF02803; TransMembrane:1 (i399-418o); go_function: GO:0016746 - transferase activity, transferring acyl groups [Evidence IEA]; go_function: GO:0016747 - transferase activity, transferring acyl groups other than amino-acyl groups [Evidence IEA] AKAW2_51543A COG:H; EggNog:ENOG410PNN2; InterPro:IPR005493,IPR036704; PFAM:PF03737 AKAW2_51544S COG:Q; EggNog:ENOG410PKHI; InterPro:IPR001447,IPR038765; PFAM:PF00797; go_function: GO:0016407 - acetyltransferase activity [Evidence IEA] AKAW2_51545A COG:S; EggNog:ENOG410PR9C; InterPro:IPR017384; PFAM:PF15879; TransMembrane:1 (o7-28i) AKAW2_51546S COG:B; EggNog:ENOG410PIDK; InterPro:IPR036388,IPR019787,IPR016181,IPR011011, IPR040706,IPR001965,IPR002717,IPR013083; PFAM:PF01853,PF16866,PF17772; go_function: GO:0004402 - histone acetyltransferase activity [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA]; go_process: GO:0016573 - histone acetylation [Evidence IEA] AKAW2_51548S COG:S; EggNog:ENOG410PQQK; InterPro:IPR038491,IPR021740,IPR037525 AKAW2_51549S COG:S; EggNog:ENOG410Q2P3; TransMembrane:1 (i762-779o) AKAW2_51550A BUSCO:EOG09264DMU; COG:F; EggNog:ENOG410PNJS; InterPro:IPR027417,IPR026681; go_function: GO:0050262 - ribosylnicotinamide kinase activity [Evidence IEA]; go_process: GO:0034356 - NAD biosynthesis via nicotinamide riboside salvage pathway [Evidence IEA] AKAW2_51551A COG:K,L; EggNog:ENOG410QDFQ; InterPro:IPR038718,IPR000330,IPR027417,IPR014001, IPR001650; PFAM:PF00176,PF00271; go_function: GO:0005524 - ATP binding [Evidence IEA] AKAW2_51552A COG:K; EggNog:ENOG410QDNX; InterPro:IPR009071,IPR036910; PFAM:PF00505,PF09011 AKAW2_51553A COG:S; EggNog:ENOG410PT07; InterPro:IPR001087,IPR036514; PFAM:PF00657; go_function: GO:0016788 - hydrolase activity, acting on ester bonds [Evidence IEA] AKAW2_51554S COG:J; EggNog:ENOG410PHTT; InterPro:IPR014401,IPR018282,IPR001377; PFAM:PF01092; go_component: GO:0005840 - ribosome [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_process: GO:0006412 - translation [Evidence IEA] AKAW2_51555A COG:F; EggNog:ENOG410PGG8; InterPro:IPR029057,IPR000836,IPR000842,IPR029099, IPR005946; PFAM:PF00156,PF14572,PF13793; go_function: GO:0000287 - magnesium ion binding [Evidence IEA]; go_function: GO:0004749 - ribose phosphate diphosphokinase activity [Evidence IEA]; go_process: GO:0009116 - nucleoside metabolic process [Evidence IEA]; go_process: GO:0009156 - ribonucleoside monophosphate biosynthetic process [Evidence IEA]; go_process: GO:0009165 - nucleotide biosynthetic process [Evidence IEA]; go_process: GO:0044249 - cellular biosynthetic process [Evidence IEA] AKAW2_51556A COG:O; EggNog:ENOG410PHS9; InterPro:IPR016024,IPR035983,IPR025527,IPR000569, IPR010314,IPR010309; PFAM:PF14377,PF06012,PF00632,PF06025; TransMembrane:2 (o1229-1250i1291-1308o); go_function: GO:0004842 - ubiquitin-protein transferase activity [Evidence IEA] AKAW2_51557A COG:Q; EggNog:ENOG410PGWA; InterPro:IPR037120,IPR034812,IPR036396,IPR019791, IPR017972,IPR001128,IPR010255; go_function: GO:0004601 - peroxidase activity [Evidence IEA]; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0006979 - response to oxidative stress [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_51558S BUSCO:EOG09263FR7; COG:I; EggNog:ENOG410PKTC; InterPro:IPR001104,IPR039357; PFAM:PF02544,PF04191; TransMembrane:6 (i91-109o129-146i167-184o196-216i237-257o263-282i); go_function: GO:0016627 - oxidoreductase activity, acting on the CH-CH group of donors [Evidence IEA]; go_process: GO:0006629 - lipid metabolic process [Evidence IEA] AKAW2_51559A CAZy:GT34; COG:G; EggNog:ENOG410PI6F; InterPro:IPR008630; PFAM:PF05637; TransMembrane:1 (i30-52o); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0016757 - transferase activity, transferring glycosyl groups [Evidence IEA] AKAW2_51560A BUSCO:EOG09263ZBJ; COG:J; EggNog:ENOG410PJC5; InterPro:IPR034704,IPR026569,IPR037147; PFAM:PF00830; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA] AKAW2_51561S COG:L; EggNog:ENOG410PHI2; InterPro:IPR027238,IPR037938,IPR027417,IPR003593, IPR041048,IPR010339; PFAM:PF17856,PF06068; go_component: GO:0031011 - Ino80 complex [Evidence IEA]; go_component: GO:0035267 - NuA4 histone acetyltransferase complex [Evidence IEA]; go_component: GO:0097255 - R2TP complex [Evidence IEA]; go_function: GO:0003678 - DNA helicase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0043139 - 5'-3' DNA helicase activity [Evidence IEA] AKAW2_51562A COG:S; EggNog:ENOG410PGJC; InterPro:IPR002937,IPR036188; TransMembrane:1 (o500-521i); go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_51563S COG:U; EggNog:ENOG410PUSH; InterPro:IPR000727,IPR038407,IPR010989,IPR007705; PFAM:PF12352,PF05008; go_component: GO:0016020 - membrane [Evidence IEA]; go_process: GO:0006886 - intracellular protein transport [Evidence IEA]; go_process: GO:0016192 - vesicle-mediated transport [Evidence IEA] AKAW2_51564A BUSCO:EOG092640WA; COG:S; EggNog:ENOG410PV8D; InterPro:IPR029071,IPR025390,IPR019413; PFAM:PF10302,PF13373; TransMembrane:2 (o287-305i317-336o) AKAW2_51565S COG:K; EggNog:ENOG410PMRV; InterPro:IPR007219; PFAM:PF04082; TransMembrane:4 (i121-137o164-183i339-358o416-435i); go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA] AKAW2_51566S COG:Q; EggNog:ENOG410PJN3; InterPro:IPR008775; PFAM:PF05721 AKAW2_51567A COG:P; EggNog:ENOG410PMYF; InterPro:IPR017870,IPR035903,IPR000361,IPR016092; PFAM:PF01521; go_function: GO:0005198 - structural molecule activity [Evidence IEA]; go_function: GO:0051536 - iron-sulfur cluster binding [Evidence IEA]; go_process: GO:0097428 - protein maturation by iron-sulfur cluster transfer [Evidence IEA] AKAW2_51568S COG:Z; EggNog:ENOG410PGUI; InterPro:IPR013636,IPR039868; PFAM:PF08427; TransMembrane:1 (o431-448i) AKAW2_51569A COG:B; EggNog:ENOG410PMN5; InterPro:IPR038217,IPR016197,IPR025995,IPR008676, IPR026541,IPR000953; PFAM:PF05712,PF11717; go_component: GO:0005634 - nucleus [Evidence IEA]; go_process: GO:0006325 - chromatin organization [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_51570S COG:S; EggNog:ENOG410PS5C; InterPro:IPR018565; PFAM:PF09447; go_component: GO:0000776 - kinetochore [Evidence IEA] AKAW2_51571S COG:S; EggNog:ENOG410PQUV; InterPro:IPR018607; PFAM:PF09696; go_component: GO:0031390 - Ctf18 RFC-like complex [Evidence IEA]; go_process: GO:0007064 - mitotic sister chromatid cohesion [Evidence IEA] AKAW2_51572S COG:S; EggNog:ENOG410PT0Y; InterPro:IPR011008,IPR013097; PFAM:PF07876 AKAW2_51573A COG:U; EggNog:ENOG410PHI4; InterPro:IPR035969,IPR000195; PFAM:PF00566 AKAW2_51574A COG:O; EggNog:ENOG410PK2X; InterPro:IPR032955,IPR002088; PFAM:PF01239; go_component: GO:0005968 - Rab-protein geranylgeranyltransferase complex [Evidence IEA]; go_function: GO:0008318 - protein prenyltransferase activity [Evidence IEA]; go_process: GO:0018342 - protein prenylation [Evidence IEA]; go_process: GO:0018344 - protein geranylgeranylation [Evidence IEA] AKAW2_51575S COG:D,O; EggNog:ENOG410QD8R; InterPro:IPR036322,IPR015943,IPR033010,IPR001680, IPR017986; PFAM:PF00400; go_function: GO:0005515 - protein binding [Evidence IEA]; go_function: GO:0010997 - anaphase-promoting complex binding [Evidence IEA]; go_function: GO:0097027 - ubiquitin-protein transferase activator activity [Evidence IEA]; go_process: GO:1904668 - positive regulation of ubiquitin protein ligase activity [Evidence IEA] AKAW2_51576S COG:S; EggNog:ENOG410PQVS; SECRETED:SignalP(1-19) AKAW2_51577A BUSCO:EOG09264NJ1; COG:A; EggNog:ENOG410PGRK; InterPro:IPR015943,IPR036322,IPR007148; PFAM:PF04003; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_51578S COG:K; EggNog:ENOG410PH11; InterPro:IPR036427,IPR001487,IPR027353,IPR038336, IPR018359; PFAM:PF00439,PF17035; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_51579S COG:S; EggNog:ENOG410PKZP AKAW2_51580S COG:S; EggNog:ENOG410PRY8; InterPro:IPR007872,IPR036671; PFAM:PF05207 AKAW2_51581A BUSCO:EOG092659DX; COG:P; EggNog:ENOG410PRTK; InterPro:IPR036524,IPR020895,IPR017789,IPR002908; PFAM:PF01491; go_component: GO:0005739 - mitochondrion [Evidence IEA]; go_function: GO:0004322 - ferroxidase activity [Evidence IEA]; go_function: GO:0008199 - ferric iron binding [Evidence IEA]; go_process: GO:0016226 - iron-sulfur cluster assembly [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_51583S COG:S; EggNog:ENOG410PVRV; InterPro:IPR009210 AKAW2_51582A BUSCO:EOG09260K5F; COG:U; EggNog:ENOG410PGB5; InterPro:IPR010326,IPR042532; PFAM:PF06046; go_component: GO:0000145 - exocyst [Evidence IEA]; go_process: GO:0006887 - exocytosis [Evidence IEA] AKAW2_51584S COG:J; EggNog:ENOG410PST3; InterPro:IPR036919,IPR016082,IPR005996; PFAM:PF00327; antiSMASH:Cluster_5.19; go_component: GO:0015934 - large ribosomal subunit [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_process: GO:0006412 - translation [Evidence IEA] AKAW2_51585A COG:E; EggNog:ENOG410PIG6; InterPro:IPR015424,IPR002129,IPR015421,IPR015422; PFAM:PF00282; SMCOG1180:Decarboxylase, pyridoxal-dependent; TransMembrane:2 (o25-43i64-82o); antiSMASH:Cluster_5.19; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0016831 - carboxy-lyase activity [Evidence IEA]; go_function: GO:0030170 - pyridoxal phosphate binding [Evidence IEA]; go_process: GO:0019752 - carboxylic acid metabolic process [Evidence IEA] AKAW2_51586A COG:E; EggNog:ENOG410PIJD; InterPro:IPR002034,IPR011872,IPR000891,IPR013785; PFAM:PF00682; SMCOG1271:2-isopropylmalate synthase; antiSMASH:Cluster_5.19; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0004410 - homocitrate synthase activity [Evidence IEA]; go_function: GO:0046912 - transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer [Evidence IEA]; go_process: GO:0019752 - carboxylic acid metabolic process [Evidence IEA]; go_process: GO:0019878 - lysine biosynthetic process via aminoadipic acid [Evidence IEA] AKAW2_51587S COG:S; EggNog:ENOG410PMIS; InterPro:IPR036864,IPR021858,IPR001138; PFAM:PF00172,PF11951; antiSMASH:Cluster_5.19; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_51588S COG:G; EggNog:ENOG410PIBT; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; SMCOG1005:Drug resistance transporter, EmrB/QacA; TransMembrane:13 (o91-109i121-140o146-167i179-198o210-229i250-269o281- 301i322-342o362-382i389-410o416-438i450-473o527-545i); antiSMASH:Cluster_5.19; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_51589S COG:I; EggNog:ENOG410Q1ZW; InterPro:IPR000873,IPR025110,IPR009081,IPR006162, IPR036736,IPR020845,IPR020806,IPR010071,IPR042099, IPR023213,IPR001242; PFAM:PF00501,PF00668,PF13193,PF00550; SMCOG1002:AMP-dependent synthetase and ligase; TransMembrane:2 (o1368-1387i1493-1513o); antiSMASH:Cluster_5.19; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0031177 - phosphopantetheine binding [Evidence IEA] AKAW2_51590A COG:S; EggNog:ENOG410PY3P; InterPro:IPR025714,IPR029063; PFAM:PF13649,PF13489,PF08242,PF08241,PF13847; antiSMASH:Cluster_5.19 AKAW2_51591S COG:S; EggNog:ENOG410Q1X1; InterPro:IPR029032; antiSMASH:Cluster_5.19 AKAW2_51592A COG:K; EggNog:ENOG410PZMI; InterPro:IPR036236,IPR036864,IPR007219,IPR013087, IPR001138; PFAM:PF00096; antiSMASH:Cluster_5.19; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_51594A COG:S; EggNog:ENOG410PQQR; InterPro:IPR028000; TransMembrane:1 (o58-80i); antiSMASH:Cluster_5.19 AKAW2_51593S COG:S; EggNog:ENOG410PM6C; InterPro:IPR002110,IPR020683,IPR027417,IPR007111, IPR036770; PFAM:PF05729,PF12796,PF13637,PF13606; antiSMASH:Cluster_5.19; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_51596A COG:S; EggNog:ENOG410PXC4; InterPro:IPR011009,IPR002575; PFAM:PF01636; antiSMASH:Cluster_5.19 AKAW2_51595S COG:S; EggNog:ENOG410Q1VS; InterPro:IPR025340; PFAM:PF14033; antiSMASH:Cluster_5.19 AKAW2_51597S COG:S; EggNog:ENOG410PHI8; InterPro:IPR005821; PFAM:PF00520; TransMembrane:8 (i342-359o371-388i400-424o436-456i476-496o508-528i537- 558o590-611i); go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0005216 - ion channel activity [Evidence IEA]; go_process: GO:0006811 - ion transport [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_51598S COG:S; EggNog:ENOG410PN6M AKAW2_51599S COG:U; EggNog:ENOG410PMTZ; InterPro:IPR010908,IPR042855,IPR001388,IPR011012; PFAM:PF00957,PF13774; TransMembrane:1 (i223-248o); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_process: GO:0016192 - vesicle-mediated transport [Evidence IEA] AKAW2_51600A COG:S; EggNog:ENOG410PTF1; InterPro:IPR036330,IPR018943; PFAM:PF10215; TransMembrane:1 (i7-28o) AKAW2_51601S COG:S; EggNog:ENOG410PJHV; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; TransMembrane:1 (o498-517i); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_51602A COG:U; EggNog:ENOG410PGQR; InterPro:IPR035969,IPR000195; PFAM:PF00566 AKAW2_51603S COG:Q; EggNog:ENOG410PG47; InterPro:IPR036291,IPR002347; PFAM:PF08659,PF00106,PF13561; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_51604A COG:T; EggNog:ENOG410PJ00; InterPro:IPR001194,IPR005113,IPR037516,IPR043153; PFAM:PF03456,PF02141 AKAW2_51605A BUSCO:EOG092602OP; COG:T; EggNog:ENOG410PI6P; InterPro:IPR016024,IPR011989,IPR021133,IPR008271, IPR036322,IPR001680,IPR019775,IPR000719,IPR011009, IPR017986; PFAM:PF00400,PF00069; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_51606S COG:S; EggNog:ENOG410PH97; TransMembrane:9 (o297-314i321-338o358-377i398-422o428-450i462-479o485- 509i542-560o572-591i) AKAW2_51607S COG:K; EggNog:ENOG410PK41; InterPro:IPR036236,IPR013087; PFAM:PF00096,PF12874 AKAW2_51608S BUSCO:EOG0926458I; COG:Q; EggNog:ENOG410PGVF; InterPro:IPR011876,IPR015797,IPR000086; PFAM:PF00293; go_function: GO:0004452 - isopentenyl-diphosphate delta-isomerase activity [Evidence IEA]; go_function: GO:0016787 - hydrolase activity [Evidence IEA]; go_process: GO:0008299 - isoprenoid biosynthetic process [Evidence IEA] AKAW2_51609A COG:S; EggNog:ENOG410PPKT; InterPro:IPR003807; PFAM:PF02656; TransMembrane:3 (i88-105o117-140i161-179o) AKAW2_51610S COG:L; EggNog:ENOG410PFXB; InterPro:IPR002528; PFAM:PF01554; TransMembrane:12 (i192-216o236-257i269-287o299-321i333-355o361-387i408- 429o441-463i483-503o523-544i556-574o586-606i); go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0015297 - antiporter activity [Evidence IEA]; go_function: GO:0042910 - xenobiotic transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_51611A COG:L; EggNog:ENOG410PNZK; InterPro:IPR014892,IPR036388,IPR014646,IPR036390, IPR040260,IPR012340; PFAM:PF08784; go_component: GO:0005634 - nucleus [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_process: GO:0006260 - DNA replication [Evidence IEA]; go_process: GO:0006281 - DNA repair [Evidence IEA]; go_process: GO:0006310 - DNA recombination [Evidence IEA] AKAW2_51612S COG:J; EggNog:ENOG410PHMJ; InterPro:IPR033517,IPR027417,IPR001650,IPR014014, IPR012541,IPR014001,IPR011545,IPR000629; PFAM:PF08147,PF00270,PF00271; go_component: GO:0005634 - nucleus [Evidence IEA]; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0003723 - RNA binding [Evidence IEA]; go_function: GO:0003724 - RNA helicase activity [Evidence IEA]; go_function: GO:0004386 - helicase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA] AKAW2_51613A COG:O; EggNog:ENOG410PGF2; InterPro:IPR036249,IPR036282,IPR010987,IPR004045, IPR004046; PFAM:PF13409,PF00043,PF14497,PF13410,PF13417, PF02798; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0006749 - glutathione metabolic process [Evidence IEA] AKAW2_51614A COG:Q; EggNog:ENOG410PHWX; InterPro:IPR036291,IPR002347; PFAM:PF00106,PF13561; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_51615S COG:S; EggNog:ENOG410Q0CZ; InterPro:IPR021833; PFAM:PF11905 AKAW2_51616S COG:S; EggNog:ENOG410PY2I; InterPro:IPR036864,IPR001138; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_51617S COG:Q; EggNog:ENOG410PHE8; InterPro:IPR022313,IPR001106,IPR023144,IPR024083, IPR005922,IPR008948; PFAM:PF00221; go_component: GO:0005737 - cytoplasm [Evidence IEA]; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0016841 - ammonia-lyase activity [Evidence IEA]; go_process: GO:0006559 - L-phenylalanine catabolic process [Evidence IEA] AKAW2_51618S TransMembrane:1 (o82-100i) AKAW2_51619S COG:E; EggNog:ENOG410PFCJ; InterPro:IPR002293; PFAM:PF00324,PF13520; TransMembrane:11 (o61-80i101-125o145-173i185-202o208-233i298-317o347- 366i399-415o421-443i463-482o494-516i); go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_51620S COG:B,K; EggNog:ENOG410PMHJ; InterPro:IPR036427,IPR001487,IPR037800,IPR016181, IPR000182,IPR018359; PFAM:PF00439,PF13673,PF00583; go_function: GO:0004402 - histone acetyltransferase activity [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_function: GO:0008080 - N-acetyltransferase activity [Evidence IEA] AKAW2_51621A COG:E; EggNog:ENOG410PHJU; InterPro:IPR004840,IPR004841; PFAM:PF13520,PF00324; TransMembrane:12 (i55-76o82-100i107-123o135-154i161-182o194-214i278- 295o315-342i374-397o403-424i444-466o478-498i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_process: GO:0006865 - amino acid transport [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_51622A BUSCO:EOG09260YMF; COG:A; EggNog:ENOG410PFU2; InterPro:IPR025313,IPR027417,IPR001650,IPR014014, IPR014001,IPR011545,IPR000629; PFAM:PF04851,PF00270,PF00271,PF13959; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0004386 - helicase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA] AKAW2_51623S COG:O; EggNog:ENOG410PJYX; InterPro:IPR001623,IPR036869; PFAM:PF00226 AKAW2_51624S COG:H; EggNog:ENOG410PN2E; InterPro:IPR002500,IPR014729; PFAM:PF01507; go_function: GO:0003824 - catalytic activity [Evidence IEA] AKAW2_51625A COG:S; EggNog:ENOG410PI61; InterPro:IPR000504,IPR012677,IPR035979; PFAM:PF00076; go_function: GO:0003676 - nucleic acid binding [Evidence IEA] AKAW2_51626A COG:L; EggNog:ENOG410PGWG; InterPro:IPR004871,IPR015943,IPR018846,IPR011047; PFAM:PF10433,PF03178; go_component: GO:0005634 - nucleus [Evidence IEA]; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_51627A COG:C; EggNog:ENOG410PGVU; InterPro:IPR001709,IPR001433,IPR001094,IPR017927, IPR023208,IPR023173,IPR029039,IPR008254,IPR017938, IPR039261,IPR003097; PFAM:PF00175,PF00258,PF00667; go_function: GO:0003958 - NADPH-hemoprotein reductase activity [Evidence IEA]; go_function: GO:0010181 - FMN binding [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_51628S BUSCO:EOG092601YK; COG:S; EggNog:ENOG410PGFZ; InterPro:IPR025614,IPR025481,IPR016024,IPR029473, IPR039867; PFAM:PF14222,PF14225; go_process: GO:0000902 - cell morphogenesis [Evidence IEA] AKAW2_51629S COG:E; EggNog:ENOG410PKYJ; InterPro:IPR029154,IPR002204,IPR036291,IPR006115, IPR008927,IPR013328; PFAM:PF03807,PF03446,PF14833; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0050661 - NADP binding [Evidence IEA]; go_function: GO:0051287 - NAD binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_51630S COG:S; EggNog:ENOG410PVIQ; InterPro:IPR029058 AKAW2_51631A COG:Q; EggNog:ENOG410PMRI; InterPro:IPR001128,IPR017972,IPR002401,IPR036396; PFAM:PF00067; TransMembrane:1 (i21-39o); go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_51632A COG:C,H; EggNog:ENOG410PUA1; InterPro:IPR036188,IPR002938,IPR036249,IPR038220, IPR012941; PFAM:PF07976,PF01494; go_function: GO:0071949 - FAD binding [Evidence IEA] AKAW2_51633A COG:S; EggNog:ENOG410PNBP; TransMembrane:1 (o220-238i) AKAW2_51634A COG:S; EggNog:ENOG410PTF0; InterPro:IPR011431; PFAM:PF07543; TransMembrane:1 (o48-65i) AKAW2_51635S COG:S; EggNog:ENOG410PR25; InterPro:IPR009072,IPR029003; PFAM:PF15630; go_component: GO:0071821 - FANCM-MHF complex [Evidence IEA]; go_function: GO:0046982 - protein heterodimerization activity [Evidence IEA] AKAW2_51636S COG:Q; EggNog:ENOG410PFVV; InterPro:IPR013154,IPR013149,IPR002328,IPR036291, IPR011032,IPR020843; PFAM:PF00107,PF08240,PF13602; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_51637A COG:G; EggNog:ENOG410PF97; InterPro:IPR005829,IPR005828,IPR003663,IPR036259, IPR020846; PFAM:PF00083; TransMembrane:12 (i60-91o111-131i138-156o162-184i196-216o236-257i320- 339o351-372i379-401o407-434i446-469o481-500i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_51638S COG:S; EggNog:ENOG410PK73; InterPro:IPR008775; PFAM:PF05721 AKAW2_51639S CAZy:CE10; COG:I; EggNog:ENOG410PNHB; InterPro:IPR029058,IPR013094; PFAM:PF07859; TransMembrane:1 (o22-46i); go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_51640A COG:I; EggNog:ENOG410PP2D; InterPro:IPR019819,IPR019826,IPR002018,IPR029058; MEROPS:MER0030934; PFAM:PF00135; SECRETED:SignalP(1-19) AKAW2_51641A COG:D; EggNog:ENOG410PKD1 AKAW2_51642S COG:Q; EggNog:ENOG410PIG4; InterPro:IPR020946,IPR036188; PFAM:PF13738,PF13450,PF07992,PF00743; TransMembrane:3 (o18-37i460-480o486-503i); go_function: GO:0004499 - N,N-dimethylaniline monooxygenase activity [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_function: GO:0050661 - NADP binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_51643A COG:C; EggNog:ENOG410PK95; InterPro:IPR006094,IPR040165,IPR036318,IPR016166, IPR016169; PFAM:PF01565; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_function: GO:0071949 - FAD binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_51644A COG:F; EggNog:ENOG410PFD0; InterPro:IPR029052,IPR006179,IPR008334,IPR041821, IPR036907; PFAM:PF02872; go_function: GO:0016787 - hydrolase activity [Evidence IEA]; go_process: GO:0009166 - nucleotide catabolic process [Evidence IEA] AKAW2_51645A COG:S; EggNog:ENOG410PPNE; InterPro:IPR011057,IPR006913; PFAM:PF04828; go_function: GO:0016846 - carbon-sulfur lyase activity [Evidence IEA] AKAW2_51646A COG:K; EggNog:ENOG410Q2P5; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_51647S InterPro:IPR025951; PFAM:PF14231; SECRETED:SignalP(1-29) AKAW2_51648A InterPro:IPR002110,IPR020683,IPR036770; PFAM:PF00023,PF12796; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_51649S COG:S; EggNog:ENOG410PIYI; InterPro:IPR011118,IPR029058; PFAM:PF07519; SECRETED:SignalP(1-20) AKAW2_51650A COG:G; EggNog:ENOG410PK79; InterPro:IPR029033 AKAW2_51651S COG:U; EggNog:ENOG410QE3B; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:14 (i67-94o106-128i135-155o167-185i197-221o227-249i261- 284o296-314i334-354o374-390i397-416o422-447i459-480o500- 521i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_51652S COG:S; EggNog:ENOG410PIMQ; InterPro:IPR022105,IPR022099,IPR027417; PFAM:PF12340,PF12359 AKAW2_51653A COG:S; EggNog:ENOG410PTH8 AKAW2_51654S CAZy:AA3; COG:E; EggNog:ENOG410PFGF; InterPro:IPR012132,IPR036188,IPR000172,IPR007867; PFAM:PF05199,PF00732; go_function: GO:0016614 - oxidoreductase activity, acting on CH-OH group of donors [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_51655A COG:S; EggNog:ENOG410PSAU AKAW2_51657A COG:S; EggNog:ENOG410Q1Z1; SECRETED:SignalP(1-19); TransMembrane:1 (n5-16c21/22o263-289i) AKAW2_51658A COG:T; EggNog:ENOG410PIFQ; InterPro:IPR019826,IPR019819,IPR002018,IPR029058; MEROPS:MER0033198; PFAM:PF00135,PF07859; SECRETED:SignalP(1-24) AKAW2_51659A COG:G; EggNog:ENOG410PKF5; InterPro:IPR032710 AKAW2_51660A CAZy:AA7; COG:C; EggNog:ENOG410PV25; InterPro:IPR006094,IPR036318,IPR016164,IPR016166, IPR012951; PFAM:PF08031,PF01565; TransMembrane:2 (o6-26i38-57o); go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_function: GO:0071949 - FAD binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_51662S COG:S; EggNog:ENOG410PRGT; InterPro:IPR019258; PFAM:PF10018; go_component: GO:0016592 - mediator complex [Evidence IEA]; go_function: GO:0003712 - transcription coregulator activity [Evidence IEA]; go_process: GO:0006357 - regulation of transcription by RNA polymerase II [Evidence IEA] AKAW2_51661A COG:G; EggNog:ENOG410PJEN; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:11 (o67-90i102-123o135-152i195-212o224-243i328-351o371- 393i414-435o441-462i474-490o510-530i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_51663A COG:S; EggNog:ENOG410Q2PD; InterPro:IPR036864,IPR021858,IPR001138; PFAM:PF00172,PF11951; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_51665S COG:S; EggNog:ENOG410PXQZ; TransMembrane:6 (i7-30o87-108i120-139o159-183i204-220o240-266i) AKAW2_51666S COG:S; EggNog:ENOG410PX36 AKAW2_51667S COG:Q; EggNog:ENOG410PKT8; InterPro:IPR036291,IPR002347; PFAM:PF08659,PF00106,PF13561; TransMembrane:1 (i153-176o); go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_51668A CAZy:CE10; COG:V; EggNog:ENOG410PM74; InterPro:IPR029058,IPR013094; MEROPS:MER0034665; PFAM:PF07859; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_51669S CAZy:GH92; COG:G; EggNog:ENOG410PM7C; InterPro:IPR041371,IPR014718,IPR012939,IPR008928, IPR005887; PFAM:PF17678,PF07971; SECRETED:SignalP(1-23); go_function: GO:0030246 - carbohydrate binding [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_51670A COG:S; EggNog:ENOG410PN0M; InterPro:IPR040632 AKAW2_51672S COG:S; EggNog:ENOG410PWXV; InterPro:IPR016035,IPR002641; PFAM:PF01734; TransMembrane:1 (i48-66o); go_process: GO:0006629 - lipid metabolic process [Evidence IEA] AKAW2_51673S COG:S; EggNog:ENOG410Q2TG AKAW2_51674S COG:S; EggNog:ENOG410PUJE; InterPro:IPR008979; PFAM:PF17132; SECRETED:SignalP(1-24) AKAW2_51675S COG:A; EggNog:ENOG410PJNY; InterPro:IPR007855; PFAM:PF05183; go_function: GO:0003968 - RNA-directed 5'-3' RNA polymerase activity [Evidence IEA] AKAW2_51676A CAZy:AA1; COG:Q; EggNog:ENOG410PGU0; InterPro:IPR008972,IPR011707,IPR011706,IPR001117; PFAM:PF00394,PF07732,PF07731; SECRETED:SignalP(1-17); go_function: GO:0005507 - copper ion binding [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_51677S COG:S; EggNog:ENOG410PV1Q; InterPro:IPR007219; PFAM:PF04082; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA] AKAW2_51678S COG:Q; EggNog:ENOG410PKZK; InterPro:IPR002347,IPR036291,IPR020904; PFAM:PF00106,PF13561,PF08659; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_51679S COG:I; EggNog:ENOG410Q2UN; InterPro:IPR016035,IPR002641; PFAM:PF01734; go_process: GO:0006629 - lipid metabolic process [Evidence IEA] AKAW2_51680S COG:S; EggNog:ENOG410PRQD; InterPro:IPR021487; PFAM:PF11338 AKAW2_51681A COG:C; EggNog:ENOG410PMIJ; InterPro:IPR015590,IPR012394,IPR016160,IPR016161, IPR016162,IPR016163; PFAM:PF00171; TransMembrane:1 (o483-501i); go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0016620 - oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Evidence IEA]; go_process: GO:0006081 - cellular aldehyde metabolic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_51683A COG:G; EggNog:ENOG410PMAK; InterPro:IPR020846,IPR005828,IPR036259; PFAM:PF00083; TransMembrane:10 (i12-34o70-91i98-117o123-146i158-177o189-209i337-360o372- 393i405-426o438-456i); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_51682S COG:P; EggNog:ENOG410PFR8; InterPro:IPR017850,IPR000917,IPR024607; PFAM:PF00884; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0008484 - sulfuric ester hydrolase activity [Evidence IEA] AKAW2_51684A COG:S; EggNog:ENOG410PHRQ; InterPro:IPR035969,IPR000195; PFAM:PF00566 AKAW2_51685S BUSCO:EOG0926073O; COG:B; EggNog:ENOG410PG8V; InterPro:IPR001154,IPR034157,IPR013757,IPR013758, IPR013759,IPR013760,IPR003594,IPR036890,IPR013506, IPR006171,IPR002205,IPR001241,IPR020568,IPR031660, IPR014721,IPR018522; PFAM:PF16898,PF01751,PF02518,PF00521,PF00204; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0003918 - DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006259 - DNA metabolic process [Evidence IEA]; go_process: GO:0006265 - DNA topological change [Evidence IEA] AKAW2_51686S COG:G; EggNog:ENOG410Q07H; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i96-115o127-151i163-183o189-214i221-241o253-272i329- 348o368-390i465-484o496-517i529-551o557-578i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_51687A COG:S; EggNog:ENOG410PJ6A; InterPro:IPR036887,IPR003163; TransMembrane:1 (i21-41o); go_function: GO:0003677 - DNA binding [Evidence IEA] AKAW2_51688A COG:S; EggNog:ENOG410PM8T; InterPro:IPR039130,IPR005635; PFAM:PF03941; go_process: GO:0000070 - mitotic sister chromatid segregation [Evidence IEA]; go_process: GO:1902412 - regulation of mitotic cytokinesis [Evidence IEA] AKAW2_51689S COG:S; EggNog:ENOG410PJJ6; InterPro:IPR003388; PFAM:PF02453; TransMembrane:4 (i71-89o95-117i165-182o188-206i) AKAW2_51690A COG:S; EggNog:ENOG410PSMP; InterPro:IPR021264; PFAM:PF11001 AKAW2_51691S COG:S; EggNog:ENOG410PT80 AKAW2_51692S COG:O; EggNog:ENOG410PGCA; InterPro:IPR036034,IPR009003,IPR041489,IPR001940, IPR025926,IPR001478; MEROPS:MER0003297; PFAM:PF17820,PF12812,PF13365; go_function: GO:0004252 - serine-type endopeptidase activity [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0006508 - proteolysis [Evidence IEA] AKAW2_51693A InterPro:IPR032675 AKAW2_51694A COG:O; EggNog:ENOG410PIDA; InterPro:IPR011990,IPR044059,IPR019734,IPR013026; PFAM:PF18972; go_function: GO:0005515 - protein binding [Evidence IEA]; go_function: GO:0051879 - Hsp90 protein binding [Evidence IEA] AKAW2_51697S COG:U; EggNog:ENOG410QE3B; InterPro:IPR011701,IPR036259; PFAM:PF07690; TransMembrane:8 (i25-44o56-76i88-113o133-151i158-177o183-209i221-243o263- 284i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_51698S CAZy:AA2; COG:C; EggNog:ENOG410PIDX; InterPro:IPR019794,IPR002207,IPR010255,IPR002016; PFAM:PF00141; go_function: GO:0004601 - peroxidase activity [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0006979 - response to oxidative stress [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_51699A COG:S; EggNog:ENOG410PUIC AKAW2_51700S BUSCO:EOG09264YEG; COG:J; EggNog:ENOG410PG18; InterPro:IPR010979,IPR001892,IPR018269,IPR027437; PFAM:PF00416; go_component: GO:0005840 - ribosome [Evidence IEA]; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0003723 - RNA binding [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_process: GO:0006412 - translation [Evidence IEA] AKAW2_51701A COG:O; EggNog:ENOG410PFU0; InterPro:IPR029058,IPR018202,IPR008442,IPR001563; MEROPS:MER0002010; PFAM:PF05388,PF00450; SECRETED:SignalP(1-15); go_component: GO:0005773 - vacuole [Evidence IEA]; go_function: GO:0004185 - serine-type carboxypeptidase activity [Evidence IEA]; go_process: GO:0006508 - proteolysis [Evidence IEA] AKAW2_51702S BUSCO:EOG0926400M; COG:J; EggNog:ENOG410PFAQ; InterPro:IPR002140,IPR018978,IPR019783,IPR036786, IPR039100,IPR037188; PFAM:PF09377,PF01172; go_process: GO:0042254 - ribosome biogenesis [Evidence IEA]; go_process: GO:0042256 - mature ribosome assembly [Evidence IEA] AKAW2_51703A COG:T; EggNog:ENOG410PM5P; InterPro:IPR000719,IPR011009,IPR008271; PFAM:PF07714,PF00069; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_51704A COG:S; EggNog:ENOG410PZNX AKAW2_51705S COG:S; EggNog:ENOG410Q2I0 AKAW2_51706S COG:E; EggNog:ENOG410PJVE; InterPro:IPR010107,IPR002129,IPR015424,IPR015421; PFAM:PF00282,PF00266; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0004351 - glutamate decarboxylase activity [Evidence IEA]; go_function: GO:0016831 - carboxy-lyase activity [Evidence IEA]; go_function: GO:0030170 - pyridoxal phosphate binding [Evidence IEA]; go_process: GO:0006536 - glutamate metabolic process [Evidence IEA]; go_process: GO:0019752 - carboxylic acid metabolic process [Evidence IEA] AKAW2_51707S COG:S; EggNog:ENOG410PJ4M AKAW2_51708A COG:S; EggNog:ENOG410PPPK; TransMembrane:5 (o118-138i231-253o273-291i348-367o373-393i) AKAW2_51709A COG:S; EggNog:ENOG410PXA0; InterPro:IPR000182,IPR016181; PFAM:PF13508,PF00583; go_function: GO:0008080 - N-acetyltransferase activity [Evidence IEA] AKAW2_51710S COG:S; EggNog:ENOG410PQ7I; InterPro:IPR024320; PFAM:PF09924 AKAW2_51712A COG:C; EggNog:ENOG410PIZW; InterPro:IPR014756,IPR036374,IPR005066,IPR008335, IPR000572; PFAM:PF00174,PF03404; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0030151 - molybdenum ion binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_51713A COG:P; EggNog:ENOG410PHB8; InterPro:IPR018028,IPR011614,IPR024708,IPR020835, IPR024711,IPR037060,IPR010582; PFAM:PF00199,PF06628; go_function: GO:0004096 - catalase activity [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0006979 - response to oxidative stress [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_51714A COG:S; EggNog:ENOG410PPWU; InterPro:IPR005302,IPR011037; PFAM:PF03473; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0030151 - molybdenum ion binding [Evidence IEA]; go_function: GO:0030170 - pyridoxal phosphate binding [Evidence IEA] AKAW2_51715A COG:E; EggNog:ENOG410PJXQ; InterPro:IPR036526,IPR003010; PFAM:PF00795; go_process: GO:0006807 - nitrogen compound metabolic process [Evidence IEA] AKAW2_51716A COG:P; EggNog:ENOG410PKN7; InterPro:IPR025863,IPR017785,IPR017850,IPR024607, IPR000917; PFAM:PF12411,PF01663,PF00884; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0008484 - sulfuric ester hydrolase activity [Evidence IEA] AKAW2_51718A BUSCO:EOG09261FH7; COG:U; EggNog:ENOG410PI2V; InterPro:IPR004240; PFAM:PF02990; TransMembrane:9 (n12-19c24/25o305-326i403-430o436-456i477-497o503-525i556- 581o593-618i630-654o666-695i); go_component: GO:0016021 - integral component of membrane [Evidence IEA] AKAW2_51719A BUSCO:EOG09264JQ1; COG:O; EggNog:ENOG410PHFJ; InterPro:IPR029071,IPR006636,IPR015940,IPR000626, IPR009060; PFAM:PF00240,PF11976,PF00627,PF13881; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_51720S BUSCO:EOG092607OQ; COG:A; EggNog:ENOG410PGD2; InterPro:IPR018846,IPR036322,IPR004871,IPR015943, IPR011044; PFAM:PF10433,PF03178; TransMembrane:1 (o942-962i); go_component: GO:0005634 - nucleus [Evidence IEA]; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_51721A COG:I,J,T; EggNog:ENOG410PKS2; InterPro:IPR023631,IPR036928; PFAM:PF01425 AKAW2_51722A CAZy:GH18; COG:G; EggNog:ENOG410PH2N; InterPro:IPR011583,IPR029070,IPR001223,IPR017853, IPR001579; PFAM:PF00704; SECRETED:SignalP(1-17); go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_function: GO:0008061 - chitin binding [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_51723S COG:S; EggNog:ENOG410PJ77; InterPro:IPR011021,IPR014752; PFAM:PF00339 AKAW2_51724A COG:S; EggNog:ENOG410Q1ZV AKAW2_51725A COG:O; EggNog:ENOG410PUK6; InterPro:IPR036249,IPR040079,IPR036282,IPR010987, IPR004045; PFAM:PF13409,PF13417,PF02798; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0006749 - glutathione metabolic process [Evidence IEA] AKAW2_51726A BUSCO:EOG0926051U; COG:J; EggNog:ENOG410PFH1; InterPro:IPR016024,IPR011989,IPR021133,IPR040191, IPR012954,IPR022125; PFAM:PF08146,PF12397; TransMembrane:2 (n2-9c14/15o947-963i999-1023o) AKAW2_51727S COG:S; EggNog:ENOG410PHZK; InterPro:IPR013633,IPR003107,IPR011990; PFAM:PF08424; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0006396 - RNA processing [Evidence IEA] AKAW2_51728A COG:S; EggNog:ENOG410PYE1; InterPro:IPR010730; PFAM:PF06985 AKAW2_51729A COG:Q; EggNog:ENOG410PUQX; InterPro:IPR020946,IPR036188; PFAM:PF13450; TransMembrane:1 (i78-95o); go_function: GO:0004499 - N,N-dimethylaniline monooxygenase activity [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_function: GO:0050661 - NADP binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_51730S COG:J; EggNog:ENOG410PH3S; InterPro:IPR036100,IPR042118,IPR042119,IPR003699; PFAM:PF02547; go_function: GO:0016740 - transferase activity [Evidence IEA]; go_function: GO:0016853 - isomerase activity [Evidence IEA] AKAW2_51731S COG:K; EggNog:ENOG410Q2P9; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_51732S COG:G; EggNog:ENOG410Q2B1; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i68-93o130-150i157-175o181-204i216-237o249-266i307- 327o342-365i400-417o423-446i467-484o490-512i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_51733S COG:S; EggNog:ENOG410Q23W; InterPro:IPR036236,IPR013087,IPR007219; PFAM:PF00096,PF04082; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA] AKAW2_51734S COG:C; EggNog:ENOG410PGTG; InterPro:IPR001155,IPR013785; PFAM:PF00724; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0010181 - FMN binding [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_51735S COG:S; EggNog:ENOG410PRFZ; InterPro:IPR021054; PFAM:PF12296; SECRETED:SignalP(1-18) AKAW2_51736A COG:I; EggNog:ENOG410PJW8; InterPro:IPR006176,IPR022694,IPR006108,IPR036291, IPR008927,IPR013328; PFAM:PF02737,PF01210,PF00725; go_function: GO:0003857 - 3-hydroxyacyl-CoA dehydrogenase activity [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0070403 - NAD+ binding [Evidence IEA]; go_process: GO:0006631 - fatty acid metabolic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_51737A COG:C; EggNog:ENOG410PK92; InterPro:IPR001834,IPR008333,IPR001433,IPR001199, IPR017927,IPR001709,IPR036400,IPR018506,IPR017938, IPR039261; PFAM:PF00173,PF00175,PF00970; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_51738S COG:Q; EggNog:ENOG410PFCN; InterPro:IPR001128,IPR002403,IPR036396; PFAM:PF00067; TransMembrane:1 (i342-366o); go_function: GO:0004497 - monooxygenase activity [Evidence IEA]; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_51739S COG:K; EggNog:ENOG410PVUX; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_51740A COG:Q; EggNog:ENOG410PWA3; InterPro:IPR004294; PFAM:PF03055; go_function: GO:0016702 - oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_51741S CAZy:AA4; COG:C; EggNog:ENOG410PUXT; InterPro:IPR016171,IPR016170,IPR006094,IPR036318, IPR016169,IPR016164,IPR016166,IPR016167; PFAM:PF01565; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_function: GO:0071949 - FAD binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_51742A COG:U; EggNog:ENOG410PWMU; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; TransMembrane:2 (i262-281o578-599i); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_51743A COG:Q; EggNog:ENOG410PM3R; InterPro:IPR001128,IPR036396; PFAM:PF00067; TransMembrane:1 (n3-13c17/18o210-228i); go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_51744S InterPro:IPR020915; PFAM:PF11578 AKAW2_51745A COG:S; EggNog:ENOG410PITJ; InterPro:IPR036291 AKAW2_51746S COG:S; EggNog:ENOG410PIN6; InterPro:IPR006076,IPR036188; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_51747S COG:H; EggNog:ENOG410PJ29; InterPro:IPR008949; PFAM:PF19086 AKAW2_51748A CAZy:GH71; COG:G; EggNog:ENOG410PJGT; InterPro:IPR005197; PFAM:PF03659; SECRETED:SignalP(1-20); go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_51749A COG:S; EggNog:ENOG410PV2V; InterPro:IPR036864,IPR001138; PFAM:PF00172; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_51750A COG:S; EggNog:ENOG410PNIK; InterPro:IPR029062,IPR002818; PFAM:PF01965 AKAW2_51751A COG:S; EggNog:ENOG410PN1U; TransMembrane:2 (i17-37o57-83i) AKAW2_51752S COG:Q; EggNog:ENOG410PKT8; InterPro:IPR036291,IPR002347; PFAM:PF08659,PF00106,PF13561; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_51753S COG:S; EggNog:ENOG410PWCY; InterPro:IPR014710,IPR011051,IPR025979; PFAM:PF12973 AKAW2_51754A COG:K; EggNog:ENOG410PVDB; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_51755A COG:S; EggNog:ENOG410Q1Z5 AKAW2_51756A COG:C; EggNog:ENOG410PJ9A; InterPro:IPR023210,IPR036812; PFAM:PF00248 AKAW2_51757A COG:S; EggNog:ENOG410PP0G; InterPro:IPR006680,IPR032466,IPR032465; PFAM:PF04909; SECRETED:SignalP(1-19); go_function: GO:0016787 - hydrolase activity [Evidence IEA]; go_function: GO:0016831 - carboxy-lyase activity [Evidence IEA] AKAW2_51758S COG:S; EggNog:ENOG410PKP8; TransMembrane:7 (o55-75i96-116o136-158i167-188o213-237i249-271o283-303i) AKAW2_51759A COG:Q; EggNog:ENOG410PV4Y; InterPro:IPR001128,IPR017972,IPR002401,IPR036396; PFAM:PF00067; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_51761S TransMembrane:1 (o96-117i) AKAW2_51762A COG:S; EggNog:ENOG410PK5T; InterPro:IPR037473,IPR018713; PFAM:PF09995; TransMembrane:1 (o353-378i) AKAW2_51763S COG:C; EggNog:ENOG410PK95; InterPro:IPR006094,IPR040165,IPR036318,IPR016166, IPR016169; PFAM:PF01565; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_function: GO:0071949 - FAD binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_51764A SECRETED:SignalP(1-30) AKAW2_51765A COG:S; EggNog:ENOG410PH8E; InterPro:IPR007312,IPR017850; PFAM:PF04185; SECRETED:SignalP(1-16); TransMembrane:1 (n4-15c22/23o452-470i); go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0016788 - hydrolase activity, acting on ester bonds [Evidence IEA] AKAW2_51766A COG:S; EggNog:ENOG410PJ4D; InterPro:IPR036291 AKAW2_51767A COG:C; EggNog:ENOG410Q1JE; InterPro:IPR044053; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA] AKAW2_51768A SECRETED:SignalP(1-18) AKAW2_51769A COG:S; EggNog:ENOG410PYCC AKAW2_51770A COG:S; EggNog:ENOG410PYCC; TransMembrane:4 (o42-63i131-158o170-188i200-217o) AKAW2_51771S COG:S; EggNog:ENOG410PPPN; InterPro:IPR004235,IPR032710; PFAM:PF02982,PF13577; go_function: GO:0030411 - scytalone dehydratase activity [Evidence IEA]; go_process: GO:0006582 - melanin metabolic process [Evidence IEA] AKAW2_51772A COG:S; EggNog:ENOG410Q2K5; InterPro:IPR007219; PFAM:PF04082; TransMembrane:1 (o405-422i); go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA] AKAW2_51773A COG:Q; EggNog:ENOG410PFCN; InterPro:IPR001128,IPR002403,IPR036396; PFAM:PF00067; TransMembrane:1 (o344-368i); go_function: GO:0004497 - monooxygenase activity [Evidence IEA]; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_51774S COG:G; EggNog:ENOG410PJ3T; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i45-73o85-104i116-135o141-160i172-193o205-229i250- 272o278-299i311-333o339-362i374-396o402-422i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_51775A COG:Q; EggNog:ENOG410PW54; InterPro:IPR001128,IPR017972,IPR002401,IPR036396; PFAM:PF00067; TransMembrane:1 (o6-28i); go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_51776S COG:T; EggNog:ENOG410PXP6; InterPro:IPR011009 AKAW2_51777S COG:S; EggNog:ENOG410PWF2; InterPro:IPR011990,IPR027417,IPR041664,IPR031359; PFAM:PF13191,PF17100; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_51778A COG:G; EggNog:ENOG410PJKA; InterPro:IPR028356,IPR028357,IPR036220,IPR036291, IPR001732,IPR014027,IPR014026,IPR017476,IPR008927; PFAM:PF00984,PF03720; go_function: GO:0003979 - UDP-glucose 6-dehydrogenase activity [Evidence IEA]; go_function: GO:0016616 - oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Evidence IEA]; go_function: GO:0051287 - NAD binding [Evidence IEA]; go_process: GO:0000271 - polysaccharide biosynthetic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_51779A CAZy:GT2_Glyco_tranf_2; COG:S; EggNog:ENOG410PJ0I; InterPro:IPR029044; PFAM:PF13506,PF00535,PF13641; SECRETED:SignalP(1-21); TransMembrane:2 (i302-321o341-365i) AKAW2_51780A COG:P,Q; EggNog:ENOG410PFUK; InterPro:IPR017938,IPR017927,IPR013130,IPR013121, IPR039261,IPR013112; PFAM:PF08022,PF01794,PF08030; TransMembrane:5 (i14-36o56-77i98-119o139-157i169-188o); go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_51781S COG:S; EggNog:ENOG410PP7I; SECRETED:SignalP(1-27); TransMembrane:4 (i12-36o73-92i104-122o128-153i) AKAW2_51782S COG:L; EggNog:ENOG410PVGU; InterPro:IPR015637,IPR036895,IPR005122; PFAM:PF03167; go_function: GO:0019104 - DNA N-glycosylase activity [Evidence IEA]; go_process: GO:0006281 - DNA repair [Evidence IEA] AKAW2_51783A COG:S; EggNog:ENOG410PRJB; InterPro:IPR036786,IPR039100,IPR019783; PFAM:PF01172 AKAW2_51784A COG:T; EggNog:ENOG410PIJ2; InterPro:IPR000219,IPR001331,IPR035899; PFAM:PF00621; go_function: GO:0005085 - guanyl-nucleotide exchange factor activity [Evidence IEA]; go_process: GO:0035556 - intracellular signal transduction [Evidence IEA] AKAW2_51785S COG:O; EggNog:ENOG410PGUB; InterPro:IPR041489,IPR035269,IPR036034,IPR040815; PFAM:PF18265,PF17820,PF00595; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0070682 - proteasome regulatory particle assembly [Evidence IEA] AKAW2_51786S BUSCO:EOG09264LKR; COG:U; EggNog:ENOG410PFRI; InterPro:IPR005225,IPR001806,IPR027417,IPR002041; PFAM:PF00025,PF08477,PF00071; go_function: GO:0003924 - GTPase activity [Evidence IEA]; go_function: GO:0005525 - GTP binding [Evidence IEA]; go_process: GO:0006913 - nucleocytoplasmic transport [Evidence IEA] AKAW2_51787A COG:K,L; EggNog:ENOG410QDFW; InterPro:IPR001841,IPR027417,IPR000330,IPR038718, IPR001650,IPR014001,IPR013083; PFAM:PF13923,PF00176,PF13920,PF00097,PF13445, PF00271,PF04851; go_function: GO:0005524 - ATP binding [Evidence IEA] AKAW2_51788S COG:Q; EggNog:ENOG410PI6J; InterPro:IPR001128,IPR002403,IPR017972,IPR036396; PFAM:PF00067; go_function: GO:0004497 - monooxygenase activity [Evidence IEA]; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_51789S COG:S; EggNog:ENOG410PQ08; InterPro:IPR036527,IPR003033,IPR039543; PFAM:PF02036 AKAW2_51790S COG:U; EggNog:ENOG410PSJ1; InterPro:IPR000156,IPR015007,IPR011993; PFAM:PF08911,PF00638; go_component: GO:0005643 - nuclear pore [Evidence IEA]; go_process: GO:0046907 - intracellular transport [Evidence IEA] AKAW2_51791A BUSCO:EOG09265EOF; COG:J; EggNog:ENOG410PP8V; InterPro:IPR023621,IPR000054; PFAM:PF01198; go_component: GO:0005840 - ribosome [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_process: GO:0006412 - translation [Evidence IEA] AKAW2_51792A COG:E; EggNog:ENOG410PFZN; InterPro:IPR036526,IPR001110,IPR003010; PFAM:PF00795; go_process: GO:0006807 - nitrogen compound metabolic process [Evidence IEA] AKAW2_51793S TransMembrane:3 (n21-32c39/40o49-67i192-216o222-239i) AKAW2_51794A COG:I; EggNog:ENOG410PWJI; InterPro:IPR036291,IPR026055,IPR013120; PFAM:PF07993; go_function: GO:0080019 - fatty-acyl-CoA reductase (alcohol-forming) activity [Evidence IEA] AKAW2_51795S COG:S; EggNog:ENOG410Q28Y; InterPro:IPR021842; PFAM:PF11917 AKAW2_51796S InterPro:IPR036047,IPR032675; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_51797A COG:S; EggNog:ENOG410PU90; InterPro:IPR022198; PFAM:PF12520; SECRETED:SignalP(1-21) AKAW2_51798S COG:S; EggNog:ENOG410PSMF; InterPro:IPR000719,IPR011009; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_51799A COG:S; EggNog:ENOG410Q1UX AKAW2_51800A COG:P,Q; EggNog:ENOG410PW93; InterPro:IPR017938,IPR017927,IPR013130,IPR013121, IPR039261,IPR013112; PFAM:PF08022,PF01794; TransMembrane:7 (n3-11c16/17o26-48i60-78o98-115i127-144o159-179i186- 203o215-237i); go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_51801A InterPro:IPR018957,IPR013083; PFAM:PF00097; go_function: GO:0046872 - metal ion binding [Evidence IEA] AKAW2_51802A COG:S; EggNog:ENOG410Q03K AKAW2_51803A COG:S; EggNog:ENOG410PS4M; InterPro:IPR008972; SECRETED:SignalP(1-20); TransMembrane:1 (n5-15c20/21o263-284i) AKAW2_51804S COG:S; EggNog:ENOG410PYYC AKAW2_51805A COG:S; EggNog:ENOG410PNGW; InterPro:IPR029063; PFAM:PF08242,PF13489,PF08241,PF13649 AKAW2_51809S COG:S; EggNog:ENOG410PW16 AKAW2_51810S COG:O; EggNog:ENOG410PN65; InterPro:IPR016035 AKAW2_51811A InterPro:IPR003347 AKAW2_51813A COG:S; EggNog:ENOG410PUUG; InterPro:IPR011009 AKAW2_51814A COG:L; EggNog:ENOG410PS5H; InterPro:IPR015797,IPR000086; PFAM:PF00293; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_51816S COG:S; EggNog:ENOG410PXXJ; TransMembrane:1 (o6-23i) AKAW2_51817S COG:T; EggNog:ENOG410PUMK; InterPro:IPR000719,IPR011009; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_51819S COG:S; EggNog:ENOG410PYUF AKAW2_51820A COG:S; EggNog:ENOG410Q1MS AKAW2_51821S COG:S; EggNog:ENOG410PUSJ; InterPro:IPR036864,IPR001138; PFAM:PF00172; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_51822A COG:M; EggNog:ENOG410PVCT; InterPro:IPR029044,IPR007577; PFAM:PF04488; TransMembrane:2 (i259-281o330-350i) AKAW2_51823S COG:S; EggNog:ENOG410PJXJ; InterPro:IPR007568; PFAM:PF04479; TransMembrane:7 (o36-56i63-84o96-121i142-163o183-208i229-251o271-299i); go_component: GO:0016021 - integral component of membrane [Evidence IEA] AKAW2_51824A BUSCO:EOG092602MO; COG:U; EggNog:ENOG410PG7X; InterPro:IPR026885,IPR026849,IPR026886,IPR015412; PFAM:PF13329,PF09333; go_process: GO:0006914 - autophagy [Evidence IEA]; go_process: GO:0030242 - autophagy of peroxisome [Evidence IEA] AKAW2_51825A COG:F; EggNog:ENOG410PFVF; InterPro:IPR001365,IPR032466; PFAM:PF00962; go_function: GO:0019239 - deaminase activity [Evidence IEA] AKAW2_51826S COG:F,P; EggNog:ENOG410PFWI; InterPro:IPR011657,IPR008276,IPR002668; PFAM:PF07662,PF01773; TransMembrane:12 (i86-106o112-138i159-180o192-207i214-234o276-296i308- 333o353-375i444-465o477-495i539-563o575-597i); go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0005337 - nucleoside transmembrane transporter activity [Evidence IEA]; go_process: GO:1901642 - nucleoside transmembrane transport [Evidence IEA] AKAW2_51827A COG:O; EggNog:ENOG410PNQ1; InterPro:IPR016135,IPR023313,IPR000608; PFAM:PF00179 AKAW2_51828S COG:D; EggNog:ENOG410PG25; InterPro:IPR008271,IPR000719,IPR011009; PFAM:PF07714,PF14531,PF00069; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_51829S COG:S; EggNog:ENOG410PIFW; InterPro:IPR001810,IPR036322,IPR039719,IPR036047; PFAM:PF00646,PF12937; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_51830S BUSCO:EOG09263Z8I; COG:H; EggNog:ENOG410QEE6; InterPro:IPR000422,IPR017945; PFAM:PF00926; go_function: GO:0008686 - 3,4-dihydroxy-2-butanone-4-phosphate synthase activity [Evidence IEA]; go_process: GO:0009231 - riboflavin biosynthetic process [Evidence IEA] AKAW2_51831A BUSCO:EOG09264CND; COG:K; EggNog:ENOG410PHVN; InterPro:IPR040501,IPR003166,IPR016656; PFAM:PF18121,PF02186; go_component: GO:0005673 - transcription factor TFIIE complex [Evidence IEA]; go_process: GO:0006367 - transcription initiation from RNA polymerase II promoter [Evidence IEA] AKAW2_51832S COG:U; EggNog:ENOG410QDMI; InterPro:IPR012929; PFAM:PF07926; go_process: GO:0006606 - protein import into nucleus [Evidence IEA] AKAW2_51833A BUSCO:EOG092651OF; COG:S; EggNog:ENOG410PNWG; InterPro:IPR035679,IPR010036,IPR010033,IPR036412, IPR023214; PFAM:PF12689; go_function: GO:0016791 - phosphatase activity [Evidence IEA] AKAW2_51834A COG:S; EggNog:ENOG410PW80; InterPro:IPR001611; PFAM:PF00560; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_51835A COG:A; EggNog:ENOG410PFEF; InterPro:IPR004179,IPR027417,IPR036390,IPR001650, IPR014001,IPR011545; PFAM:PF02889,PF04851,PF00270,PF00271; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA] AKAW2_51836A COG:G; EggNog:ENOG410PJIB; InterPro:IPR007271; PFAM:PF04142; TransMembrane:9 (o19-37i49-72o131-148i157-174o231-252i272-288o304-326i333- 351o357-376i); go_component: GO:0000139 - Golgi membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0015165 - pyrimidine nucleotide-sugar transmembrane transporter activity [Evidence IEA]; go_process: GO:0090481 - pyrimidine nucleotide-sugar transmembrane transport [Evidence IEA] AKAW2_51837A COG:S; EggNog:ENOG410PXXG AKAW2_51838A COG:B; EggNog:ENOG410PM3T; InterPro:IPR036570,IPR000489,IPR011011,IPR003511, IPR013083; PFAM:PF02301; go_process: GO:0042558 - pteridine-containing compound metabolic process [Evidence IEA] AKAW2_51839S COG:D; EggNog:ENOG410PH5S; InterPro:IPR001810,IPR036322,IPR015943,IPR001680, IPR036047,IPR019775,IPR020472,IPR017986; PFAM:PF00646,PF00400,PF12937; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_51840A COG:S; EggNog:ENOG410PKVI; InterPro:IPR019987,IPR027417,IPR006073,IPR030393; PFAM:PF01926; go_function: GO:0005525 - GTP binding [Evidence IEA] AKAW2_51841S BUSCO:EOG09265FGA; COG:U; EggNog:ENOG410PJBE; InterPro:IPR016635,IPR011012,IPR022775,IPR027155; PFAM:PF01217; go_component: GO:0030123 - AP-3 adaptor complex [Evidence IEA]; go_process: GO:0006896 - Golgi to vacuole transport [Evidence IEA]; go_process: GO:0015031 - protein transport [Evidence IEA] AKAW2_51842S COG:J; EggNog:ENOG410PHEE; InterPro:IPR004038,IPR001921,IPR029064,IPR018492, IPR004037,IPR038524; PFAM:PF01248; go_component: GO:1990904 - ribonucleoprotein complex [Evidence IEA]; go_process: GO:0042254 - ribosome biogenesis [Evidence IEA] AKAW2_51843A BUSCO:EOG09260GR8; COG:Z; EggNog:ENOG410Q5EE; InterPro:IPR016024,IPR034085,IPR011989 AKAW2_51844A COG:S; EggNog:ENOG410PRF2; InterPro:IPR012340,IPR000266; PFAM:PF00366; go_component: GO:0005840 - ribosome [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_process: GO:0006412 - translation [Evidence IEA] AKAW2_51845A CAZy:GT20; COG:G; EggNog:ENOG410PFBQ; InterPro:IPR012766,IPR001830; PFAM:PF00982; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0003825 - alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity [Evidence IEA]; go_process: GO:0005992 - trehalose biosynthetic process [Evidence IEA] AKAW2_51846A COG:S; EggNog:ENOG410PG1P; InterPro:IPR036866,IPR036388,IPR041516,IPR001279; PFAM:PF17778,PF00753 AKAW2_51847A COG:C; EggNog:ENOG410PGE5; InterPro:IPR001030,IPR018136,IPR006248,IPR036008, IPR015931,IPR015932,IPR015928,IPR000573; PFAM:PF00694,PF00330; go_function: GO:0003994 - aconitate hydratase activity [Evidence IEA]; go_function: GO:0051539 - 4 iron, 4 sulfur cluster binding [Evidence IEA]; go_process: GO:0006099 - tricarboxylic acid cycle [Evidence IEA] AKAW2_51848S COG:A; EggNog:ENOG410PMXD; InterPro:IPR036236,IPR013087,IPR022755,IPR003604; PFAM:PF12171; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA] AKAW2_51849A COG:C; EggNog:ENOG410PI84; InterPro:IPR018108,IPR023395,IPR002067; PFAM:PF00153; TransMembrane:2 (o6-25i55-77o); go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_51850S COG:L; EggNog:ENOG410PG5P; InterPro:IPR038718,IPR000330,IPR027417,IPR001650, IPR013967,IPR014001; PFAM:PF00176,PF00271,PF04851,PF08658; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016817 - hydrolase activity, acting on acid anhydrides [Evidence IEA] AKAW2_51851S BUSCO:EOG09260M87; COG:L; EggNog:ENOG410PFWP; InterPro:IPR016024,IPR011989,IPR021133,IPR026825, IPR021841; PFAM:PF02985,PF11916,PF12755; go_component: GO:0070772 - PAS complex [Evidence IEA]; go_process: GO:0006661 - phosphatidylinositol biosynthetic process [Evidence IEA] AKAW2_51852A COG:S; EggNog:ENOG410PSH8 AKAW2_51853A COG:Q; EggNog:ENOG410PFX8; InterPro:IPR017871,IPR027417,IPR003593,IPR039421, IPR011527,IPR003439,IPR036640; PFAM:PF00005,PF00664; TransMembrane:1 (o27-48i); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA]; go_function: GO:0042626 - ATPase-coupled transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_51854S COG:S; EggNog:ENOG410PMMW; InterPro:IPR016031,IPR002838,IPR036983; PFAM:PF01987 AKAW2_51855S COG:G; EggNog:ENOG410PUY1; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i91-110o134-156i163-182o188-208i220-240o252-271i292- 311o331-348i360-379o385-410i422-443o455-473i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_51856A COG:Z; EggNog:ENOG410PJ03; InterPro:IPR036961,IPR027417,IPR027640,IPR001752, IPR010994; PFAM:PF00225,PF16796; go_function: GO:0003777 - microtubule motor activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0008017 - microtubule binding [Evidence IEA]; go_process: GO:0007018 - microtubule-based movement [Evidence IEA] AKAW2_51857S COG:U; EggNog:ENOG410PHZQ; InterPro:IPR007123,IPR036180,IPR012990,IPR036465, IPR006895,IPR006896,IPR041742,IPR036175,IPR036174, IPR006900,IPR029006; PFAM:PF04810,PF08033,PF04815,PF00626,PF04811; TransMembrane:2 (o713-731i743-762o); go_component: GO:0030127 - COPII vesicle coat [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006886 - intracellular protein transport [Evidence IEA]; go_process: GO:0006888 - endoplasmic reticulum to Golgi vesicle-mediated transport [Evidence IEA] AKAW2_51858S COG:T; EggNog:ENOG410PFNJ; InterPro:IPR017441,IPR008271,IPR003527,IPR000719, IPR011009; PFAM:PF07714,PF00069; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0004707 - MAP kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_51859A BUSCO:EOG092634MM; COG:H; EggNog:ENOG410PK2G; InterPro:IPR003754,IPR036108,IPR039793; PFAM:PF02602; go_function: GO:0004852 - uroporphyrinogen-III synthase activity [Evidence IEA]; go_process: GO:0006780 - uroporphyrinogen III biosynthetic process [Evidence IEA]; go_process: GO:0033014 - tetrapyrrole biosynthetic process [Evidence IEA] AKAW2_51860A COG:C; EggNog:ENOG410PFC2; InterPro:IPR001509,IPR036291; PFAM:PF04321,PF05368,PF13460,PF01370; go_function: GO:0003824 - catalytic activity [Evidence IEA] AKAW2_51861A COG:H; EggNog:ENOG410PRGW; InterPro:IPR029063; PFAM:PF13649,PF13489,PF01209,PF08242,PF08241, PF13847 AKAW2_51862S COG:O; EggNog:ENOG410PF9I; InterPro:IPR036390,IPR000717,IPR035298,IPR040798; PFAM:PF18261,PF01399 AKAW2_51863A BUSCO:EOG092619GP; COG:O; EggNog:ENOG410PGB3; InterPro:IPR007246; PFAM:PF04114; TransMembrane:8 (i21-42o376-396i446-466o478-497i509-527o533-550i562- 588o608-633i); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_component: GO:0042765 - GPI-anchor transamidase complex [Evidence IEA] AKAW2_51864A COG:T; EggNog:ENOG410PH0G; InterPro:IPR022764,IPR035952; MEROPS:MER0034660; PFAM:PF01694; TransMembrane:6 (i20-41o73-92i104-122o128-145i166-183o189-210i); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0004252 - serine-type endopeptidase activity [Evidence IEA] AKAW2_51865A COG:Q; EggNog:ENOG410PPKF; InterPro:IPR002925,IPR029058; PFAM:PF01738; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_51866A COG:S; EggNog:ENOG410PG2I; InterPro:IPR018827,IPR018825; PFAM:PF10355,PF10348; SECRETED:SignalP(1-22); TransMembrane:11 (n8-17c22/23o70-92i104-121o136-157i283-302o322-343i364- 383o395-414i452-469o489-506i518-542o554-576i) AKAW2_51867S COG:J; EggNog:ENOG410PRVZ; InterPro:IPR001209,IPR043140,IPR023676,IPR039744, IPR018271; PFAM:PF00253; go_component: GO:0005840 - ribosome [Evidence IEA]; go_component: GO:0015935 - small ribosomal subunit [Evidence IEA]; go_function: GO:0003723 - RNA binding [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006412 - translation [Evidence IEA] AKAW2_51869A BUSCO:EOG09265J36; COG:D; EggNog:ENOG410PPUU; InterPro:IPR013962; PFAM:PF08653; go_component: GO:0042729 - DASH complex [Evidence IEA]; go_component: GO:0072686 - mitotic spindle [Evidence IEA]; go_process: GO:0008608 - attachment of spindle microtubules to kinetochore [Evidence IEA] AKAW2_51868S COG:I; EggNog:ENOG410PG8S; InterPro:IPR011074,IPR036865,IPR036273,IPR001251; PFAM:PF00650,PF03765,PF13716; TransMembrane:1 (i70-88o) AKAW2_51870A BUSCO:EOG092658WY; COG:T; EggNog:ENOG410PQ3X; InterPro:IPR011146,IPR001310,IPR019808,IPR039384, IPR036265; PFAM:PF04677,PF11969,PF01230; go_function: GO:0003824 - catalytic activity [Evidence IEA] AKAW2_51871S COG:E; EggNog:ENOG410PG7Y; InterPro:IPR002933,IPR010158,IPR011650,IPR036264; MEROPS:MER0026469; PFAM:PF01546,PF07687; go_function: GO:0016787 - hydrolase activity [Evidence IEA]; go_function: GO:0016813 - hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines [Evidence IEA] AKAW2_51872A COG:J; EggNog:ENOG410PNYK; InterPro:IPR005326,IPR037447,IPR036388; PFAM:PF03501 AKAW2_51873S COG:S; EggNog:ENOG410PGT0; InterPro:IPR024974; PFAM:PF13019 AKAW2_51874S COG:S; EggNog:ENOG410PJ7Q; InterPro:IPR027417 AKAW2_51875S COG:T; EggNog:ENOG410PHFK; InterPro:IPR004839,IPR015424,IPR015421,IPR015422; PFAM:PF00155; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0030170 - pyridoxal phosphate binding [Evidence IEA]; go_process: GO:0009058 - biosynthetic process [Evidence IEA] AKAW2_51876A BUSCO:EOG092601KZ; COG:J; EggNog:ENOG410PGGF; InterPro:IPR009080,IPR013155,IPR004493,IPR009008, IPR002300; PFAM:PF08264; go_function: GO:0000166 - nucleotide binding [Evidence IEA]; go_function: GO:0002161 - aminoacyl-tRNA editing activity [Evidence IEA]; go_function: GO:0004812 - aminoacyl-tRNA ligase activity [Evidence IEA]; go_function: GO:0004823 - leucine-tRNA ligase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006418 - tRNA aminoacylation for protein translation [Evidence IEA]; go_process: GO:0006429 - leucyl-tRNA aminoacylation [Evidence IEA] AKAW2_51878S COG:J; EggNog:ENOG410PQK7; InterPro:IPR040049,IPR036249,IPR007741; PFAM:PF05047; go_component: GO:0005739 - mitochondrion [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA] AKAW2_51879A COG:S; EggNog:ENOG410PGNB; InterPro:IPR035952,IPR013861; PFAM:PF01694,PF08551; TransMembrane:6 (o6-27i39-61o73-90i102-120o132-153i174-207o); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_process: GO:0006890 - retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [Evidence IEA] AKAW2_51880S COG:S; EggNog:ENOG410PSPM; InterPro:IPR015943,IPR001680,IPR017986; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_51881A COG:S; EggNog:ENOG410Q5AV AKAW2_51882S BUSCO:EOG09262L1P; COG:E; EggNog:ENOG410PHJG; InterPro:IPR005256,IPR005801,IPR019999,IPR006805, IPR015890; PFAM:PF00425,PF04715; go_function: GO:0004049 - anthranilate synthase activity [Evidence IEA]; go_process: GO:0000162 - tryptophan biosynthetic process [Evidence IEA]; go_process: GO:0009058 - biosynthetic process [Evidence IEA] AKAW2_51883S BUSCO:EOG09264881; COG:F; EggNog:ENOG410PHV8; InterPro:IPR008942,IPR013809,IPR003903; PFAM:PF01417,PF02809 AKAW2_51884A COG:O; EggNog:ENOG410PFDY; InterPro:IPR003959,IPR003960,IPR027417,IPR003593, IPR015415; PFAM:PF09336,PF00004,PF07724; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA] AKAW2_51885A COG:C; EggNog:ENOG410PGAR; InterPro:IPR018108,IPR023395; PFAM:PF00153 AKAW2_51886A BUSCO:EOG092627XA; COG:O; EggNog:ENOG410PHQN; InterPro:IPR001841,IPR002867,IPR017907,IPR018957, IPR031127,IPR044066,IPR013083; PFAM:PF00097,PF01485; go_function: GO:0004842 - ubiquitin-protein transferase activity [Evidence IEA]; go_function: GO:0046872 - metal ion binding [Evidence IEA]; go_process: GO:0016567 - protein ubiquitination [Evidence IEA] AKAW2_51887A BUSCO:EOG09260RS7; COG:J; EggNog:ENOG410PFJ7; InterPro:IPR003307,IPR016021,IPR029044,IPR016024, IPR005835,IPR011004,IPR044123,IPR001451,IPR035543; PFAM:PF00483,PF00132,PF02020; go_function: GO:0005085 - guanyl-nucleotide exchange factor activity [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_function: GO:0016779 - nucleotidyltransferase activity [Evidence IEA]; go_function: GO:0031369 - translation initiation factor binding [Evidence IEA]; go_process: GO:0009058 - biosynthetic process [Evidence IEA] AKAW2_51889A BUSCO:EOG09264DYD; COG:K; EggNog:ENOG410PIDV; InterPro:IPR036388,IPR001789,IPR036390,IPR000232, IPR014402,IPR027725,IPR027718,IPR011006; PFAM:PF00447,PF00072; go_function: GO:0000156 - phosphorelay response regulator activity [Evidence IEA]; go_function: GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003700 - DNA-binding transcription factor activity [Evidence IEA]; go_function: GO:0043565 - sequence-specific DNA binding [Evidence IEA]; go_process: GO:0000160 - phosphorelay signal transduction system [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_51890S COG:O; EggNog:ENOG410PN2B; InterPro:IPR013740,IPR036249,IPR037944,IPR013766; PFAM:PF08534,PF00578; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA] AKAW2_51891A COG:T; EggNog:ENOG410PRF5; InterPro:IPR002634,IPR036065; PFAM:PF01722 AKAW2_51892S BUSCO:EOG09263UQF; COG:S; EggNog:ENOG410PK0I; InterPro:IPR002678,IPR036069 AKAW2_51893A BUSCO:EOG09260KCB; COG:U; EggNog:ENOG410Q13F; InterPro:IPR010490; PFAM:PF06419; go_component: GO:0017119 - Golgi transport complex [Evidence IEA]; go_process: GO:0006891 - intra-Golgi vesicle-mediated transport [Evidence IEA] AKAW2_51894S COG:S; EggNog:ENOG410PQ2N; InterPro:IPR026243; go_component: GO:0070652 - HAUS complex [Evidence IEA]; go_process: GO:0051225 - spindle assembly [Evidence IEA] AKAW2_51895A COG:O; EggNog:ENOG410PRTR; InterPro:IPR007250,IPR038399; PFAM:PF04119 AKAW2_51896S COG:S; EggNog:ENOG410PNSA AKAW2_51897S BUSCO:EOG09264IKZ; COG:S; EggNog:ENOG410PKHC; InterPro:IPR016123,IPR007681; PFAM:PF04603 AKAW2_51898A COG:S; EggNog:ENOG410PINN; InterPro:IPR006640,IPR035240; PFAM:PF17283,PF10263 AKAW2_51899S COG:M; EggNog:ENOG410PHH8; InterPro:IPR003440,IPR026899; PFAM:PF02364,PF14288; TransMembrane:16 (o483-502i523-548o563-583i590-613o649-670i691-713o725- 750i1329-1348o1378-1400i1421-1437o1494-1516i1587- 1609o1629-1653i1665-1690o1696-1714i1822-1846o); go_component: GO:0000148 - 1,3-beta-D-glucan synthase complex [Evidence IEA]; go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0003843 - 1,3-beta-D-glucan synthase activity [Evidence IEA]; go_process: GO:0006075 - (1->3)-beta-D-glucan biosynthetic process [Evidence IEA] AKAW2_51900S COG:O; EggNog:ENOG410PGFC; InterPro:IPR004839,IPR015424,IPR015421,IPR015422; PFAM:PF00155; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0030170 - pyridoxal phosphate binding [Evidence IEA]; go_process: GO:0009058 - biosynthetic process [Evidence IEA] AKAW2_51901S CAZy:GH17; COG:G; EggNog:ENOG410PH6W; InterPro:IPR017853; SECRETED:SignalP(1-19) AKAW2_51902A BUSCO:EOG09264MGU; COG:T,Z; EggNog:ENOG410PI83; InterPro:IPR018556,IPR016024,IPR030125; PFAM:PF09431 AKAW2_51903A CAZy:GH47; COG:G; EggNog:ENOG410PKHB; InterPro:IPR036026,IPR012341,IPR001382; PFAM:PF01532; SECRETED:SignalP(1-27); go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0004571 - mannosyl-oligosaccharide 1,2-alpha-mannosidase activity [Evidence IEA]; go_function: GO:0005509 - calcium ion binding [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_51904A TransMembrane:2 (o73-93i105-125o) AKAW2_51905A BUSCO:EOG092615CC; COG:U; EggNog:ENOG410PH3Z; InterPro:IPR007241; PFAM:PF04109; TransMembrane:6 (i236-256o289-307i456-480o539-559i579-597o645-666i); go_process: GO:0006914 - autophagy [Evidence IEA] AKAW2_51906S COG:T; EggNog:ENOG410PJIU; InterPro:IPR001936,IPR035892,IPR023152,IPR000008, IPR008936,IPR039360; PFAM:PF00168; go_process: GO:0007165 - signal transduction [Evidence IEA]; go_process: GO:0043087 - regulation of GTPase activity [Evidence IEA] AKAW2_51907A COG:S; EggNog:ENOG410PFUE; InterPro:IPR015943,IPR001680,IPR036322; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_51908S COG:S; EggNog:ENOG410PP36; InterPro:IPR043837,IPR040009; PFAM:PF19189; go_component: GO:0005739 - mitochondrion [Evidence IEA] AKAW2_51909A COG:S; EggNog:ENOG410PNI5; InterPro:IPR013718,IPR012762; PFAM:PF08511; go_function: GO:0008289 - lipid binding [Evidence IEA]; go_process: GO:0006744 - ubiquinone biosynthetic process [Evidence IEA] AKAW2_51910S COG:A; EggNog:ENOG410PJTU; InterPro:IPR000504,IPR012677,IPR035979; PFAM:PF00076; go_function: GO:0003676 - nucleic acid binding [Evidence IEA] AKAW2_51913A TransMembrane:2 (o20-37i49-81o) AKAW2_51914A COG:T; EggNog:ENOG410PIQP; InterPro:IPR043453,IPR001849,IPR033191,IPR011993; PFAM:PF00169; go_component: GO:0031932 - TORC2 complex [Evidence IEA]; go_function: GO:0005546 - phosphatidylinositol-4,5-bisphosphate binding [Evidence IEA]; go_process: GO:0016197 - endosomal transport [Evidence IEA]; go_process: GO:0030036 - actin cytoskeleton organization [Evidence IEA]; go_process: GO:0038203 - TORC2 signaling [Evidence IEA] AKAW2_51915A COG:O; EggNog:ENOG410PNSI; antiSMASH:Cluster_5.20 AKAW2_51916S BUSCO:EOG092604S1; COG:O; EggNog:ENOG410PGYH; InterPro:IPR025305,IPR001394,IPR018200,IPR028889, IPR038765; MEROPS:MER0000865; PFAM:PF13446,PF00443; antiSMASH:Cluster_5.20; go_function: GO:0004843 - thiol-dependent ubiquitin-specific protease activity [Evidence IEA]; go_process: GO:0006511 - ubiquitin-dependent protein catabolic process [Evidence IEA]; go_process: GO:0016579 - protein deubiquitination [Evidence IEA] AKAW2_51917S COG:C; EggNog:ENOG410PMDR; InterPro:IPR004165,IPR004164,IPR012792,IPR012791, IPR037171,IPR014388; PFAM:PF01144; antiSMASH:Cluster_5.20; go_function: GO:0008410 - CoA-transferase activity [Evidence IEA]; go_process: GO:0046952 - ketone body catabolic process [Evidence IEA] AKAW2_51918A COG:S; EggNog:ENOG410PTDX; InterPro:IPR037653; antiSMASH:Cluster_5.20; go_component: GO:0005739 - mitochondrion [Evidence IEA]; go_function: GO:0043022 - ribosome binding [Evidence IEA]; go_process: GO:0034551 - mitochondrial respiratory chain complex III assembly [Evidence IEA]; go_process: GO:0070131 - positive regulation of mitochondrial translation [Evidence IEA] AKAW2_51919S COG:U; EggNog:ENOG410PPN9; InterPro:IPR019325; PFAM:PF10176; TransMembrane:2 (i215-236o314-332i); antiSMASH:Cluster_5.20; go_process: GO:0007034 - vacuolar transport [Evidence IEA]; go_process: GO:0030001 - metal ion transport [Evidence IEA] AKAW2_51920S COG:S; EggNog:ENOG410PK89; antiSMASH:Cluster_5.20 AKAW2_51921A COG:I; EggNog:ENOG410PIIB; InterPro:IPR000873,IPR020845,IPR042099,IPR025110; PFAM:PF00501,PF13193; SMCOG1002:AMP-dependent synthetase and ligase; antiSMASH:Cluster_5.20 AKAW2_51922S COG:I; EggNog:ENOG410PJY1; InterPro:IPR000873,IPR025110,IPR009081,IPR006162, IPR036736,IPR020845,IPR020806,IPR042099,IPR023213, IPR001242; PFAM:PF00501,PF00668,PF13193,PF00550; SMCOG1002:AMP-dependent synthetase and ligase; antiSMASH:Cluster_5.20; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0031177 - phosphopantetheine binding [Evidence IEA] AKAW2_51923S SECRETED:SignalP(1-20); antiSMASH:Cluster_5.20 AKAW2_51924S COG:Q; EggNog:ENOG410PIHG; InterPro:IPR001128,IPR017972,IPR002401,IPR036396; PFAM:PF00067; SMCOG1034:cytochrome P450; TransMembrane:1 (o56-76i); antiSMASH:Cluster_5.20; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_51925A COG:S; EggNog:ENOG410PUTF; InterPro:IPR001279,IPR036866; antiSMASH:Cluster_5.20 AKAW2_51926A COG:I; EggNog:ENOG410PMM2; InterPro:IPR006115; antiSMASH:Cluster_5.20; go_function: GO:0050661 - NADP binding [Evidence IEA] AKAW2_51927S antiSMASH:Cluster_5.20 AKAW2_51928S COG:S; EggNog:ENOG410PPF9; InterPro:IPR021765; PFAM:PF11807; antiSMASH:Cluster_5.20; go_process: GO:0043386 - mycotoxin biosynthetic process [Evidence IEA] AKAW2_51929A COG:S; EggNog:ENOG410PWTZ; TransMembrane:7 (o24-42i54-79o99-120i132-161o181-203i215-239o251-275i); antiSMASH:Cluster_5.20 AKAW2_51930A COG:Q; EggNog:ENOG410PIYW; InterPro:IPR036237,IPR004601; PFAM:PF03851; go_function: GO:0004519 - endonuclease activity [Evidence IEA]; go_process: GO:0006289 - nucleotide-excision repair [Evidence IEA]; go_process: GO:0009411 - response to UV [Evidence IEA] AKAW2_51931A COG:S; EggNog:ENOG410PQ1U; TransMembrane:3 (o17-37i58-85o139-161i) AKAW2_51932A COG:S; EggNog:ENOG410PSHK; TransMembrane:1 (o159-181i) AKAW2_51933A BUSCO:EOG09263C4C; COG:A; EggNog:ENOG410PKD4; InterPro:IPR007146; PFAM:PF04000 AKAW2_51934S BUSCO:EOG09264RR2; COG:T; EggNog:ENOG410QD9F; InterPro:IPR011992,IPR028846,IPR002048,IPR018247; PFAM:PF00036,PF13499,PF13405,PF13202,PF13833; go_function: GO:0005509 - calcium ion binding [Evidence IEA] AKAW2_51935S COG:S; EggNog:ENOG410PY1Z; InterPro:IPR036864,IPR001138; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_51936A COG:I; EggNog:ENOG410PVH2; InterPro:IPR042099,IPR000873,IPR020845; PFAM:PF00501 AKAW2_51937S COG:T; EggNog:ENOG410PM5P; InterPro:IPR000719,IPR011009; PFAM:PF00069; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_51938A COG:S; EggNog:ENOG410PHT5; InterPro:IPR002213; go_function: GO:0008194 - UDP-glycosyltransferase activity [Evidence IEA] AKAW2_51939A COG:Z; EggNog:ENOG410PGZJ; InterPro:IPR019821,IPR036961,IPR027417,IPR027640, IPR001752; PFAM:PF16796,PF00225; go_function: GO:0003777 - microtubule motor activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0008017 - microtubule binding [Evidence IEA]; go_process: GO:0007018 - microtubule-based movement [Evidence IEA] AKAW2_51940A COG:K; EggNog:ENOG410PHPZ; InterPro:IPR016135,IPR023313,IPR000608; PFAM:PF00179 AKAW2_51941S COG:S; EggNog:ENOG410PMH8; InterPro:IPR024764,IPR024761; PFAM:PF12657,PF12660 AKAW2_51942A BUSCO:EOG09262Z2S; CAZy:GT33; COG:G; EggNog:ENOG410PG9S; InterPro:IPR026051; PFAM:PF13692; TransMembrane:2 (o6-23i111-133o); go_function: GO:0000030 - mannosyltransferase activity [Evidence IEA] AKAW2_51943S BUSCO:EOG092621CK; COG:P; EggNog:ENOG410PKY0; InterPro:IPR027469,IPR002524; PFAM:PF01545; TransMembrane:13 (o258-282i294-313o319-336i374-395o401-417i429-446o452- 470i525-544o556-574i595-614o626-647i668-691o703-721i); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0008324 - cation transmembrane transporter activity [Evidence IEA]; go_process: GO:0006812 - cation transport [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_51944S COG:I; EggNog:ENOG410PV4N; InterPro:IPR036291,IPR026055,IPR013120; PFAM:PF07993,PF01370; go_function: GO:0080019 - fatty-acyl-CoA reductase (alcohol-forming) activity [Evidence IEA] AKAW2_51945A COG:S; EggNog:ENOG410Q141; InterPro:IPR036864,IPR001138; PFAM:PF00172; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_51946S COG:S; EggNog:ENOG410PMMY; InterPro:IPR007568; PFAM:PF04479; TransMembrane:7 (o29-48i55-75o87-107i128-150o170-189i218-238o258-280i); go_component: GO:0016021 - integral component of membrane [Evidence IEA] AKAW2_51947A COG:O; EggNog:ENOG410PK18; InterPro:IPR016135,IPR023313,IPR000608; PFAM:PF00179 AKAW2_51948A COG:S; EggNog:ENOG410PQC7; TransMembrane:5 (i73-94o100-123i144-168o188-213i275-295o) AKAW2_51949S COG:S; EggNog:ENOG410PN5J; InterPro:IPR007568; PFAM:PF04479; TransMembrane:7 (o12-33i40-60o80-104i116-134o154-176i197-215o235-253i); go_component: GO:0016021 - integral component of membrane [Evidence IEA] AKAW2_51950A COG:S; EggNog:ENOG410Q02K; TransMembrane:4 (i20-39o51-72i84-105o117-141i) AKAW2_51951A COG:S; EggNog:ENOG410PTK8; InterPro:IPR008427; PFAM:PF05730; SECRETED:SignalP(1-19) AKAW2_51952A COG:C; EggNog:ENOG410PG2C; InterPro:IPR036188,IPR003953,IPR027477,IPR010960; PFAM:PF13450,PF00890; go_function: GO:0000104 - succinate dehydrogenase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_51953S COG:Q; EggNog:ENOG410PP6F; InterPro:IPR026992,IPR027443,IPR005123; PFAM:PF03171,PF14226; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_51954S InterPro:IPR029069,IPR042171; PFAM:PF13622 AKAW2_51956S COG:S; EggNog:ENOG410PJSS; InterPro:IPR029063; PFAM:PF13489,PF08241,PF13649 AKAW2_51957S COG:S; EggNog:ENOG410PK94; InterPro:IPR041492,IPR006439,IPR023198,IPR036412, IPR023214; PFAM:PF12710,PF13419; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_51958S COG:S; EggNog:ENOG410PHFD; InterPro:IPR016040,IPR036291,IPR001509; PFAM:PF05368,PF01118,PF13460; go_function: GO:0003824 - catalytic activity [Evidence IEA] AKAW2_51959A COG:J; EggNog:ENOG410PGA5; InterPro:IPR001451,IPR029044; PFAM:PF00132 AKAW2_51960A CAZy:CBM24; CAZy:GH71; COG:G; EggNog:ENOG410PM1E; InterPro:IPR005197; PFAM:PF03659; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_51961S SECRETED:SignalP(1-19) AKAW2_51962S COG:S; EggNog:ENOG410Q1VS; InterPro:IPR025340; PFAM:PF14033 AKAW2_51963S COG:G; EggNog:ENOG410PJ3D; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690,PF06609; TransMembrane:13 (i48-72o92-109i121-141o147-168i180-206o212-231i252- 273o285-302i322-342o362-379i386-407o450-473i524-544o); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_51964S COG:Q; EggNog:ENOG410PHH6; InterPro:IPR001128,IPR002401,IPR036396; PFAM:PF00067; TransMembrane:2 (o6-23i30-48o); go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_51965S COG:Q; EggNog:ENOG410PIXZ; InterPro:IPR002347,IPR036291,IPR020904; PFAM:PF00106,PF13561,PF08659; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_51966A COG:S; EggNog:ENOG410Q2MM AKAW2_51967S COG:S; EggNog:ENOG410PU0E AKAW2_51968S COG:S; EggNog:ENOG410PU0E AKAW2_51969A COG:O; EggNog:ENOG410PK6V; InterPro:IPR000641,IPR003959,IPR027417,IPR041627; PFAM:PF00004,PF17866; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA] AKAW2_51970A COG:O; EggNog:ENOG410PK6V; InterPro:IPR027417,IPR000641,IPR003959; PFAM:PF00004; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA] AKAW2_51973A COG:S; EggNog:ENOG410PWRG AKAW2_51974S COG:S; EggNog:ENOG410PJ0X; InterPro:IPR002921,IPR029058; PFAM:PF01764; go_process: GO:0006629 - lipid metabolic process [Evidence IEA] AKAW2_51975A TransMembrane:1 (i21-41o) AKAW2_51976S COG:S; EggNog:ENOG410PPE5; InterPro:IPR036864,IPR021858,IPR001138; PFAM:PF00172; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_51977A COG:S; EggNog:ENOG410PJXJ; InterPro:IPR007568; TransMembrane:7 (o32-51i63-84o96-117i137-158o199-219i240-262o282-301i); go_component: GO:0016021 - integral component of membrane [Evidence IEA] AKAW2_51978S COG:S; EggNog:ENOG410PW9Y; InterPro:IPR036851,IPR000028; PFAM:PF01328; SECRETED:SignalP(1-18); go_function: GO:0004601 - peroxidase activity [Evidence IEA] AKAW2_51979A COG:O; EggNog:ENOG410Q2XN; InterPro:IPR001466,IPR012338,IPR021860; MEROPS:MER0026262; PFAM:PF11954,PF00144 AKAW2_51980A COG:O; EggNog:ENOG410Q2XN; InterPro:IPR000845,IPR035994; PFAM:PF01048; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_process: GO:0009116 - nucleoside metabolic process [Evidence IEA] AKAW2_51981S COG:S; EggNog:ENOG410PWPU; InterPro:IPR013087; TransMembrane:1 (o800-819i) AKAW2_51982A COG:E; EggNog:ENOG410PGSZ; InterPro:IPR002821,IPR008040,IPR003692; PFAM:PF01968,PF05378,PF02538; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_51983A COG:K; EggNog:ENOG410PIM7; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172; TransMembrane:3 (i228-246o275-291i298-315o); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_51984S COG:Q; EggNog:ENOG410Q2H9; InterPro:IPR001128,IPR036396; TransMembrane:1 (n16-26c33/34o61-80i); go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_51985A COG:G; EggNog:ENOG410PJQU; InterPro:IPR005829,IPR005828,IPR003663,IPR036259, IPR020846; PFAM:PF00083,PF07690; TransMembrane:7 (o55-74i141-164o235-256i352-374o380-400i412-433o480-498i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_51986S COG:S; EggNog:ENOG410PY4T; InterPro:IPR000719,IPR011009; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_51987A COG:Q; EggNog:ENOG410PPAF; InterPro:IPR036291,IPR002347; PFAM:PF00106,PF13561; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_51988S COG:G; EggNog:ENOG410Q12H; InterPro:IPR014710,IPR011051,IPR013096; PFAM:PF07883 AKAW2_51989S COG:S; EggNog:ENOG410PV1W; InterPro:IPR011009 AKAW2_51990A COG:G; EggNog:ENOG410PHXX; InterPro:IPR005829,IPR005828,IPR003663,IPR036259, IPR020846; PFAM:PF00083,PF07690; TransMembrane:12 (i33-50o80-100i107-124o130-153i165-188o200-224i312- 330o350-372i379-401o413-438i459-475o481-499i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_51991S COG:S; EggNog:ENOG410PUDJ; InterPro:IPR036291,IPR016040; PFAM:PF13460 AKAW2_51992A COG:S; EggNog:ENOG410QEA1; TransMembrane:2 (i363-385o391-413i) AKAW2_51994A CAZy:GH71; COG:G; EggNog:ENOG410PGB9; InterPro:IPR005197; SECRETED:SignalP(1-22); antiSMASH:Cluster_5.21; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_51995S COG:S; EggNog:ENOG410Q2AW; antiSMASH:Cluster_5.21 AKAW2_51996A COG:S; EggNog:ENOG410PPXJ; TransMembrane:7 (o22-46i58-83o103-125i137-157o181-200i212-234o254-277i); antiSMASH:Cluster_5.21 AKAW2_51997S COG:C; EggNog:ENOG410PU8F; InterPro:IPR023210,IPR036812; PFAM:PF00248; SMCOG1039:aldo/keto reductase family oxidoreductase; antiSMASH:Cluster_5.21 AKAW2_51998S COG:S; EggNog:ENOG410Q28K; TransMembrane:1 (o174-202i); antiSMASH:Cluster_5.21 AKAW2_51999A COG:I; EggNog:ENOG410PMHS; InterPro:IPR019826,IPR002018,IPR029058; MEROPS:MER0077889; PFAM:PF00135; SECRETED:SignalP(1-16); antiSMASH:Cluster_5.21 AKAW2_52000S COG:Q; EggNog:ENOG410PHAK; InterPro:IPR001099,IPR011141,IPR012328,IPR016039, IPR018088; PFAM:PF02797,PF00195; SMCOG1024:chalcone and stilbene synthase domain protein; antiSMASH:Cluster_5.21; go_function: GO:0016746 - transferase activity, transferring acyl groups [Evidence IEA]; go_function: GO:0016747 - transferase activity, transferring acyl groups other than amino-acyl groups [Evidence IEA]; go_process: GO:0009058 - biosynthetic process [Evidence IEA] AKAW2_52001S BUSCO:EOG09263I7I; COG:C; EggNog:ENOG410PHAP; InterPro:IPR006255,IPR000089,IPR001078,IPR003016, IPR023213,IPR011053; PFAM:PF00364,PF00198; antiSMASH:Cluster_5.21; go_component: GO:0045252 - oxoglutarate dehydrogenase complex [Evidence IEA]; go_function: GO:0004149 - dihydrolipoyllysine-residue succinyltransferase activity [Evidence IEA]; go_function: GO:0016746 - transferase activity, transferring acyl groups [Evidence IEA]; go_process: GO:0006099 - tricarboxylic acid cycle [Evidence IEA] AKAW2_52002S COG:G; EggNog:ENOG410PFJN; InterPro:IPR005475,IPR011603,IPR032106,IPR029061, IPR001017,IPR031717,IPR042179; PFAM:PF02779,PF00676,PF16078,PF16870; antiSMASH:Cluster_5.21; go_function: GO:0004591 - oxoglutarate dehydrogenase (succinyl-transferring) activity [Evidence IEA]; go_function: GO:0016624 - oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor [Evidence IEA]; go_function: GO:0030976 - thiamine pyrophosphate binding [Evidence IEA]; go_process: GO:0006099 - tricarboxylic acid cycle [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_52003A COG:G; EggNog:ENOG410PG3C; InterPro:IPR001312,IPR022673,IPR022672,IPR043129; PFAM:PF00349,PF03727; antiSMASH:Cluster_5.21; go_function: GO:0004396 - hexokinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0005536 - glucose binding [Evidence IEA]; go_function: GO:0016773 - phosphotransferase activity, alcohol group as acceptor [Evidence IEA]; go_process: GO:0001678 - cellular glucose homeostasis [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_52004A COG:T; EggNog:ENOG410PFAZ; InterPro:IPR012336,IPR026928; PFAM:PF17172; antiSMASH:Cluster_5.21 AKAW2_52005A CAZy:GH76; COG:G; EggNog:ENOG410PFRH; InterPro:IPR014480,IPR008928,IPR005198; PFAM:PF03663; SECRETED:SignalP(1-22); antiSMASH:Cluster_5.21; go_function: GO:0008496 - mannan endo-1,6-alpha-mannosidase activity [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA]; go_process: GO:0016052 - carbohydrate catabolic process [Evidence IEA] AKAW2_52006S COG:M; EggNog:ENOG410PF7T; InterPro:IPR000845,IPR035994,IPR002110,IPR027417, IPR036770,IPR020683; PFAM:PF01048,PF12796,PF00023,PF13637,PF13606; antiSMASH:Cluster_5.21; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0009116 - nucleoside metabolic process [Evidence IEA] AKAW2_52007A COG:I; EggNog:ENOG410PMHS; InterPro:IPR002018,IPR029058; MEROPS:MER0033188; PFAM:PF00135,PF07859; SECRETED:SignalP(1-19); antiSMASH:Cluster_5.21 AKAW2_52008S COG:T; EggNog:ENOG410PIFQ; InterPro:IPR029058; antiSMASH:Cluster_5.21 AKAW2_52009A COG:I; EggNog:ENOG410PHHA; InterPro:IPR002018,IPR029058; MEROPS:MER0030934; PFAM:PF00135; SECRETED:SignalP(1-22) AKAW2_52010A COG:S; EggNog:ENOG410PVTV; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_52012A COG:E,O; EggNog:ENOG410PIXH; InterPro:IPR001563,IPR029058; MEROPS:MER0016549; PFAM:PF00450; SECRETED:SignalP(1-16); go_function: GO:0004185 - serine-type carboxypeptidase activity [Evidence IEA]; go_process: GO:0006508 - proteolysis [Evidence IEA] AKAW2_52013S COG:E,G; EggNog:ENOG410PGHJ; InterPro:IPR004853; PFAM:PF03151; TransMembrane:9 (i26-46o52-72i92-118o138-164i171-192o212-233i245-264o270- 291i298-315o) AKAW2_52014A CAZy:GH35; COG:G; EggNog:ENOG410PGTY; InterPro:IPR025300,IPR025972,IPR037110,IPR008979, IPR036833,IPR018954,IPR017853,IPR001944,IPR031330; PFAM:PF13363,PF10435,PF01301,PF13364; SECRETED:SignalP(1-19); go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_52015S COG:S; EggNog:ENOG410QE8P; InterPro:IPR029069; PFAM:PF13279; TransMembrane:1 (o17-37i) AKAW2_52016S COG:S; EggNog:ENOG410PWMR; InterPro:IPR011009,IPR002575; PFAM:PF01636 AKAW2_52017A COG:G; EggNog:ENOG410PHGF; InterPro:IPR005829,IPR005828,IPR003663,IPR036259, IPR020846; PFAM:PF00083,PF07690; TransMembrane:11 (i117-135o165-186i198-216o222-245i257-281o287-307i379- 399o411-432i444-465o514-533i545-564o); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_52018S COG:S; EggNog:ENOG410PT7R AKAW2_52019A COG:S; EggNog:ENOG410PNAE; InterPro:IPR029063,IPR041698; PFAM:PF13489,PF08241,PF13649 AKAW2_52020S COG:Q; EggNog:ENOG410PHR9; InterPro:IPR015889,IPR000627; PFAM:PF00775; SECRETED:SignalP(1-17); go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0008199 - ferric iron binding [Evidence IEA]; go_function: GO:0016702 - oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [Evidence IEA]; go_process: GO:0006725 - cellular aromatic compound metabolic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_52021S COG:S; EggNog:ENOG410PYW3 AKAW2_52022A COG:O; EggNog:ENOG410PI5I; InterPro:IPR036852,IPR015366,IPR030400; MEROPS:MER0078639; PFAM:PF09286; SECRETED:SignalP(1-20); go_function: GO:0004252 - serine-type endopeptidase activity [Evidence IEA]; go_function: GO:0008236 - serine-type peptidase activity [Evidence IEA]; go_process: GO:0006508 - proteolysis [Evidence IEA] AKAW2_52023A COG:G; EggNog:ENOG410PVXK; InterPro:IPR000772,IPR002241,IPR035992,IPR041233, IPR017853,IPR013780,IPR013785; PFAM:PF17801,PF00652; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_52024S COG:S; EggNog:ENOG410Q26X; SECRETED:SignalP(1-17) AKAW2_52025A COG:S; EggNog:ENOG410PR4M; InterPro:IPR021514; PFAM:PF11374; TransMembrane:5 (o46-70i82-104o124-142i149-167o487-509i) AKAW2_52026S COG:S; EggNog:ENOG410Q22F AKAW2_52027A COG:S; EggNog:ENOG410PWK0 AKAW2_52028S CAZy:GH32; COG:G; EggNog:ENOG410PJC2; InterPro:IPR001362,IPR013148,IPR013189,IPR013320, IPR023296; PFAM:PF00251,PF08244; go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_52031A COG:S; EggNog:ENOG410PHNG; InterPro:IPR016274,IPR033379,IPR000560,IPR029033; PFAM:PF00328; SECRETED:SignalP(1-19); go_function: GO:0016791 - phosphatase activity [Evidence IEA] AKAW2_52032A COG:S; EggNog:ENOG410PMWA; TransMembrane:4 (i36-54o83-107i119-143o182-202i) AKAW2_52033S COG:Q; EggNog:ENOG410PG4C; InterPro:IPR002925,IPR029058; PFAM:PF01738; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_52034S COG:K; EggNog:ENOG410PGE6; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; TransMembrane:1 (o549-569i); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_52035S COG:U; EggNog:ENOG410QDX9; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i40-65o77-97i109-128o134-156i168-191o197-217i271-296o316- 336i357-376o382-405i417-438o450-470i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_52037A COG:S; EggNog:ENOG410PU8J AKAW2_52038A COG:S; EggNog:ENOG410Q217 AKAW2_52039A COG:I; EggNog:ENOG410Q228; InterPro:IPR037143,IPR002582,IPR004568,IPR008278, IPR014030,IPR014031,IPR016039,IPR020841; PFAM:PF01648,PF00109,PF02801; go_function: GO:0000287 - magnesium ion binding [Evidence IEA]; go_function: GO:0008897 - holo-[acyl-carrier-protein] synthase activity [Evidence IEA]; go_function: GO:0016746 - transferase activity, transferring acyl groups [Evidence IEA]; go_process: GO:0006633 - fatty acid biosynthetic process [Evidence IEA] AKAW2_52040A COG:I; EggNog:ENOG410PFY5; InterPro:IPR041550,IPR036291,IPR016035,IPR002347, IPR040899; PFAM:PF00106,PF18325,PF18314; go_function: GO:0008897 - holo-[acyl-carrier-protein] synthase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_52041S COG:C; EggNog:ENOG410PIVH; InterPro:IPR019810,IPR002020,IPR036969,IPR016142, IPR016143,IPR024176; PFAM:PF00285; TransMembrane:1 (o400-422i); go_function: GO:0046912 - transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer [Evidence IEA] AKAW2_52043S COG:K; EggNog:ENOG410Q2N9; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_52044A COG:S; EggNog:ENOG410PWBU; InterPro:IPR036148,IPR012705,IPR042188,IPR005656, IPR042183; PFAM:PF03972; antiSMASH:Cluster_5.22; go_function: GO:0016829 - lyase activity [Evidence IEA]; go_function: GO:0047547 - 2-methylcitrate dehydratase activity [Evidence IEA]; go_function: GO:0051537 - 2 iron, 2 sulfur cluster binding [Evidence IEA]; go_process: GO:0019679 - propionate metabolic process, methylcitrate cycle [Evidence IEA] AKAW2_52045S COG:I; EggNog:ENOG410Q1F8; InterPro:IPR032088,IPR003965,IPR041099,IPR029069, IPR001227,IPR014043,IPR002539,IPR040883,IPR016452, IPR016035,IPR013785,IPR013565; PFAM:PF17951,PF16073,PF17828,PF01575,PF08354, PF00698; SMCOG1021:malonyl CoA-acyl carrier protein transacylase; antiSMASH:Cluster_5.22; go_component: GO:0005835 - fatty acid synthase complex [Evidence IEA]; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0004312 - fatty acid synthase activity [Evidence IEA]; go_function: GO:0004313 - [acyl-carrier-protein] S-acetyltransferase activity [Evidence IEA]; go_function: GO:0004314 - [acyl-carrier-protein] S-malonyltransferase activity [Evidence IEA]; go_function: GO:0004317 - 3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity [Evidence IEA]; go_function: GO:0004318 - enoyl-[acyl-carrier-protein] reductase (NADH) activity [Evidence IEA]; go_function: GO:0016740 - transferase activity [Evidence IEA]; go_process: GO:0006633 - fatty acid biosynthetic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_52046S antiSMASH:Cluster_5.22 AKAW2_52047S COG:H; EggNog:ENOG410PVGX; InterPro:IPR008949,IPR000092; PFAM:PF19086,PF00348; SMCOG1182:Polyprenyl synthetase; antiSMASH:Cluster_5.22; go_process: GO:0008299 - isoprenoid biosynthetic process [Evidence IEA] AKAW2_52048A COG:C; EggNog:ENOG410PUP5; InterPro:IPR015590,IPR029510,IPR016160,IPR016161, IPR016162,IPR016163; PFAM:PF00171; SMCOG1017:aldehyde dehydrogenase; antiSMASH:Cluster_5.22; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0016620 - oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_52049S COG:B,K; EggNog:ENOG410PJDE; InterPro:IPR029035,IPR002589,IPR026590,IPR043472; PFAM:PF01661; antiSMASH:Cluster_5.22 AKAW2_52050S COG:E; EggNog:ENOG410PGT4; InterPro:IPR002937,IPR036188; PFAM:PF01593; SECRETED:SignalP(1-22); antiSMASH:Cluster_5.22; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_52051A COG:S; EggNog:ENOG410QDY3; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i61-81o101-124i131-150o156-177i189-207o219-240i331- 352o364-389i410-429o441-459i471-492o504-525i); antiSMASH:Cluster_5.22; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_52052A CAZy:GH43; COG:G; EggNog:ENOG410PKK0; InterPro:IPR008979,IPR023296,IPR006710; PFAM:PF04616; SECRETED:SignalP(1-18); go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_52053A COG:S; EggNog:ENOG410PQVD AKAW2_52054A COG:S; EggNog:ENOG410PY1P; SECRETED:SignalP(1-18) AKAW2_52055S COG:S; EggNog:ENOG410PY1P; InterPro:IPR012332; SECRETED:SignalP(1-24) AKAW2_52056S COG:E; EggNog:ENOG410PG8K; InterPro:IPR036526,IPR044149,IPR000132,IPR003010; PFAM:PF00795; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_process: GO:0006807 - nitrogen compound metabolic process [Evidence IEA] AKAW2_52057S COG:S; EggNog:ENOG410PMDK; InterPro:IPR007219; PFAM:PF04082; TransMembrane:1 (i458-479o); go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA] AKAW2_52058S COG:S; EggNog:ENOG410PSNQ; InterPro:IPR021858; TransMembrane:2 (o109-132i346-364o) AKAW2_52059A COG:Q; EggNog:ENOG410PUUK; InterPro:IPR002347,IPR036291,IPR020904; PFAM:PF00106,PF13561,PF08659; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_52060A COG:S; EggNog:ENOG410Q21N; TransMembrane:7 (o6-23i35-57o96-115i127-147o167-194i206-227o239-260i) AKAW2_52061A COG:Q; EggNog:ENOG410Q2B0; InterPro:IPR036291,IPR002347,IPR020904; PFAM:PF00106,PF13561; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_52062A COG:Q; EggNog:ENOG410Q2B0; InterPro:IPR041492,IPR023198,IPR036412,IPR023214; PFAM:PF00702,PF13242,PF12710,PF13419 AKAW2_52063S COG:O; EggNog:ENOG410PGF2; InterPro:IPR036249,IPR036282,IPR010987,IPR004045, IPR004046; PFAM:PF13409,PF00043,PF14497,PF13410,PF13417, PF02798; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0006749 - glutathione metabolic process [Evidence IEA] AKAW2_52064S COG:G; EggNog:ENOG410Q2KP; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i40-60o80-100i107-125o137-155i167-190o196-215i267- 293o305-328i349-369o381-403i415-438o444-464i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_52065A COG:G; EggNog:ENOG410PV5W; InterPro:IPR005829,IPR005828,IPR003663,IPR036259, IPR020846; PFAM:PF00083,PF07690; SECRETED:SignalP(1-25); TransMembrane:10 (i12-30o67-86i121-141o156-176i183-203o311-329i341-359o365- 384i410-428o440-459i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_52066S CAZy:GH3; COG:G; EggNog:ENOG410PVNS; InterPro:IPR017853,IPR036962,IPR037524,IPR008979, IPR002772,IPR036881,IPR026891,IPR013783,IPR001764, IPR011658; PFAM:PF00933,PF01915,PF14310,PF07691; go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_52067S COG:K; EggNog:ENOG410QDU3; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_52068S COG:S; EggNog:ENOG410PWDK; InterPro:IPR011009,IPR002575; PFAM:PF01636 AKAW2_52069A CAZy:GH28; COG:G; EggNog:ENOG410PHHF; InterPro:IPR000743,IPR012334,IPR011050; PFAM:PF00295,PF12708; SECRETED:SignalP(1-18); go_function: GO:0004650 - polygalacturonase activity [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_52070S COG:C; EggNog:ENOG410PVYD; InterPro:IPR013149,IPR036291; PFAM:PF00107; TransMembrane:1 (o20-42i); go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_52071A COG:S; EggNog:ENOG410PPRF; InterPro:IPR002110,IPR036770,IPR020683; PFAM:PF13857,PF12796,PF00023,PF13637,PF13606; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_52072S COG:S; EggNog:ENOG410PT1S AKAW2_52074A InterPro:IPR013216,IPR029063; PFAM:PF08241; go_function: GO:0008168 - methyltransferase activity [Evidence IEA] AKAW2_52075S SECRETED:SignalP(1-18) AKAW2_52076A COG:G; EggNog:ENOG410PJKR; InterPro:IPR011701,IPR036259; TransMembrane:10 (i12-41o53-75i82-101o107-128i140-159o171-191i217-237o279- 297i304-324o399-420i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_52077S COG:S; EggNog:ENOG410Q1G4; InterPro:IPR001279,IPR036866; PFAM:PF13483,PF12706 AKAW2_60001S COG:E; EggNog:ENOG410Q1V4; InterPro:IPR029036,IPR008927; PFAM:PF14748; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_60002A COG:S; EggNog:ENOG410PWP7; InterPro:IPR014710,IPR011051 AKAW2_60003S COG:Q; EggNog:ENOG410PUQX; InterPro:IPR020946,IPR036188; PFAM:PF07992,PF13450; go_function: GO:0004499 - N,N-dimethylaniline monooxygenase activity [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_function: GO:0050661 - NADP binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_60004A COG:S; EggNog:ENOG410PMHC; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_60005A COG:S; EggNog:ENOG410PR8P; InterPro:IPR000182,IPR016181; PFAM:PF08445,PF00583,PF13302; go_function: GO:0008080 - N-acetyltransferase activity [Evidence IEA] AKAW2_60006A COG:S; EggNog:ENOG410Q2WR; InterPro:IPR018466; PFAM:PF10342; SECRETED:SignalP(1-18) AKAW2_60007A CAZy:GH13; COG:G; EggNog:ENOG410Q24G; InterPro:IPR006047,IPR015340,IPR017853,IPR013780, IPR013777; PFAM:PF00128,PF09260; TransMembrane:1 (o495-517i); go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0004556 - alpha-amylase activity [Evidence IEA]; go_function: GO:0005509 - calcium ion binding [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA]; go_process: GO:0016052 - carbohydrate catabolic process [Evidence IEA] AKAW2_60008A COG:S; EggNog:ENOG410QDN7; InterPro:IPR012337,IPR036397,IPR002156; PFAM:PF00075; TransMembrane:1 (o89-108i); go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0004523 - RNA-DNA hybrid ribonuclease activity [Evidence IEA] AKAW2_60009S CAZy:GH13; CAZy:GT5; COG:M; EggNog:ENOG410PF9V; InterPro:IPR013534,IPR006047,IPR017853; PFAM:PF08323,PF00128; SECRETED:SignalP(1-23); TransMembrane:3 (n11-18c23/24o1080-1105i1969-1991o2003-2021i); go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_60010S COG:S; EggNog:ENOG410PYRI; SECRETED:SignalP(1-21) AKAW2_60011A COG:Q; EggNog:ENOG410PHXR; InterPro:IPR013154,IPR013149,IPR036291,IPR011032; PFAM:PF00107,PF08240; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_60012S COG:Q; EggNog:ENOG410PJA1; InterPro:IPR036291,IPR013968 AKAW2_60013S InterPro:IPR004030,IPR036119; PFAM:PF02898; go_function: GO:0004517 - nitric-oxide synthase activity [Evidence IEA]; go_process: GO:0006809 - nitric oxide biosynthetic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_60014S COG:S; EggNog:ENOG410PY0R; SECRETED:SignalP(1-18); TransMembrane:1 (n2-12c18/19o200-221i) AKAW2_60015S COG:Z; EggNog:ENOG410QEDV; InterPro:IPR000845,IPR011990,IPR035994,IPR027417, IPR019734,IPR002182,IPR013026; PFAM:PF13374,PF01048,PF00931,PF13181,PF13424, PF07721,PF13432,PF17874,PF01535,PF13176; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_function: GO:0043531 - ADP binding [Evidence IEA]; go_process: GO:0009116 - nucleoside metabolic process [Evidence IEA] AKAW2_60016A COG:S; EggNog:ENOG410PY6Y; InterPro:IPR000073,IPR029058; PFAM:PF12697,PF00561 AKAW2_60017A COG:V; EggNog:ENOG410PN7G; InterPro:IPR036291,IPR001509; PFAM:PF13460,PF01370; go_function: GO:0003824 - catalytic activity [Evidence IEA] AKAW2_60018S COG:Q; EggNog:ENOG410PKHI; InterPro:IPR001447,IPR038765; PFAM:PF00797; go_function: GO:0016407 - acetyltransferase activity [Evidence IEA] AKAW2_60019A SECRETED:SignalP(1-19) AKAW2_60020A COG:Q; EggNog:ENOG410PKBB; InterPro:IPR036291,IPR002347; PFAM:PF00106,PF13561,PF01370; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_60022A CAZy:GH26; COG:G; EggNog:ENOG410PGZP; InterPro:IPR017853,IPR022790,IPR000805; PFAM:PF02156; SECRETED:SignalP(1-18); go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_function: GO:0016985 - mannan endo-1,4-beta-mannosidase activity [Evidence IEA]; go_process: GO:0006080 - substituted mannan metabolic process [Evidence IEA] AKAW2_60024S COG:K; EggNog:ENOG410PHJM; InterPro:IPR036864,IPR001138; PFAM:PF00172; TransMembrane:3 (o437-452i464-481o487-507i); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_60025A COG:E; EggNog:ENOG410PKD7; InterPro:IPR033940,IPR001030,IPR036008,IPR015931, IPR011827,IPR015928,IPR000573; PFAM:PF00330; go_function: GO:0016836 - hydro-lyase activity [Evidence IEA] AKAW2_60026S COG:C; EggNog:ENOG410QDJN; InterPro:IPR039556,IPR018523,IPR015813,IPR040442; PFAM:PF13714; TransMembrane:1 (o232-251i); go_function: GO:0003824 - catalytic activity [Evidence IEA] AKAW2_60027S COG:S; EggNog:ENOG410PQPM; InterPro:IPR005349; PFAM:PF03647; TransMembrane:4 (o27-45i52-70o76-94i101-120o); go_component: GO:0016020 - membrane [Evidence IEA] AKAW2_60028A COG:S; EggNog:ENOG410PNBI; InterPro:IPR038656,IPR000250,IPR013320; MEROPS:MER0001321; PFAM:PF01828; SECRETED:SignalP(1-18); go_function: GO:0004190 - aspartic-type endopeptidase activity [Evidence IEA]; go_process: GO:0006508 - proteolysis [Evidence IEA] AKAW2_60029S COG:S; EggNog:ENOG410PNG9; InterPro:IPR008922,IPR002227; PFAM:PF00264; SECRETED:SignalP(1-20); go_function: GO:0016491 - oxidoreductase activity [Evidence IEA] AKAW2_60031A SECRETED:SignalP(1-18) AKAW2_60032A COG:U; EggNog:ENOG410PMZM; InterPro:IPR011701,IPR036259; PFAM:PF07690; TransMembrane:10 (i23-42o141-166i178-200o206-226i276-298o318-336i348- 368o374-395i407-432o438-461i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_60033A COG:G; EggNog:ENOG410PJJE; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i39-56o76-97i109-133o139-157i169-190o202-222i270-287o307- 324i336-356o362-384i396-417o429-450i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_60034S COG:E; EggNog:ENOG410PK56; InterPro:IPR006076,IPR036188; PFAM:PF01266; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_60035A COG:G; EggNog:ENOG410PMGT; InterPro:IPR012083,IPR017850,IPR024607,IPR000917; PFAM:PF01663,PF00884; SECRETED:SignalP(1-15); go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0004065 - arylsulfatase activity [Evidence IEA]; go_function: GO:0008484 - sulfuric ester hydrolase activity [Evidence IEA]; go_process: GO:0018958 - phenol-containing compound metabolic process [Evidence IEA] AKAW2_60036A COG:S; EggNog:ENOG410PYBV; SECRETED:SignalP(1-17) AKAW2_60037A COG:E; EggNog:ENOG410PJ8V; InterPro:IPR013057; PFAM:PF01490; TransMembrane:11 (i60-80o86-106i134-159o165-184i196-217o237-256i276- 297o317-337i358-384o390-411i423-446o) AKAW2_60038A TransMembrane:1 (n2-13c18/19o28-48i) AKAW2_60041S COG:I; EggNog:ENOG410PH4X; InterPro:IPR001242; go_function: GO:0003824 - catalytic activity [Evidence IEA] AKAW2_60043S COG:S; EggNog:ENOG410PSBM; InterPro:IPR001345,IPR029033; SECRETED:SignalP(1-20); go_function: GO:0003824 - catalytic activity [Evidence IEA] AKAW2_60044S COG:E; EggNog:ENOG410PFC6; InterPro:IPR000109,IPR036259; PFAM:PF00854; TransMembrane:10 (i131-150o156-179i191-208o249-268i275-296o406-427i439- 461o481-505i517-539o545-565i); go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_60045A COG:G; EggNog:ENOG410PI1D; InterPro:IPR029056,IPR011877,IPR011611,IPR002139; PFAM:PF00294; go_function: GO:0004747 - ribokinase activity [Evidence IEA]; go_function: GO:0016301 - kinase activity [Evidence IEA]; go_process: GO:0006014 - D-ribose metabolic process [Evidence IEA] AKAW2_60046S COG:I; EggNog:ENOG410PMD3; InterPro:IPR003819; PFAM:PF02668; TransMembrane:2 (i220-237o243-261i); go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_60047S COG:S; EggNog:ENOG410PP28; SECRETED:SignalP(1-19) AKAW2_60048A COG:S; EggNog:ENOG410PNPP; InterPro:IPR029058; TransMembrane:7 (o28-47i59-80o100-127i139-160o184-208i220-242o254-277i) AKAW2_60049A COG:T; EggNog:ENOG410PFII; InterPro:IPR004813; PFAM:PF03169; TransMembrane:15 (i102-120o132-154i175-197o209-229i270-289o295-321i342- 360o425-443i485-510o516-535i602-625o675-692i699-718o724- 740i752-773o); go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_60051S COG:C; EggNog:ENOG410PHMP; InterPro:IPR006109,IPR006168,IPR017751,IPR036291, IPR011128,IPR008927,IPR013328; PFAM:PF01210,PF07479; go_component: GO:0009331 - glycerol-3-phosphate dehydrogenase complex [Evidence IEA]; go_function: GO:0004367 - glycerol-3-phosphate dehydrogenase [NAD+] activity [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0016616 - oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Evidence IEA]; go_function: GO:0042803 - protein homodimerization activity [Evidence IEA]; go_function: GO:0051287 - NAD binding [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA]; go_process: GO:0006072 - glycerol-3-phosphate metabolic process [Evidence IEA]; go_process: GO:0046168 - glycerol-3-phosphate catabolic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_60052A COG:S; EggNog:ENOG410PSXE; InterPro:IPR018824; PFAM:PF10346 AKAW2_60053S COG:S; EggNog:ENOG410Q1AF; InterPro:IPR036508,IPR002557; PFAM:PF01607; SECRETED:SignalP(1-22); go_component: GO:0005576 - extracellular region [Evidence IEA]; go_function: GO:0008061 - chitin binding [Evidence IEA] AKAW2_60054A COG:C; EggNog:ENOG410Q17Z; InterPro:IPR036188,IPR023753; PFAM:PF07992,PF00070; TransMembrane:1 (o12-34i); go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_60055S COG:S; EggNog:ENOG410QDYX; InterPro:IPR036864,IPR021858,IPR001138; PFAM:PF00172,PF11951; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_60056A COG:Q; EggNog:ENOG410PVV6; InterPro:IPR015168; PFAM:PF09084 AKAW2_60057A COG:S; EggNog:ENOG410QDYX; InterPro:IPR036864,IPR021858,IPR001138; PFAM:PF00172; TransMembrane:1 (i153-171o); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_60058S COG:M; EggNog:ENOG410PY8W; InterPro:IPR002110,IPR020683,IPR025676,IPR036770; PFAM:PF12796,PF00023,PF13637,PF13606,PF14420; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_60059A COG:S; EggNog:ENOG410PIY2; InterPro:IPR011009,IPR002575 AKAW2_60060A COG:S; EggNog:ENOG410QEE1; InterPro:IPR027417,IPR011990; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_60061A COG:S; EggNog:ENOG410PKTV; TransMembrane:2 (i15-41o61-80i) AKAW2_60062A COG:S; EggNog:ENOG410PKTV; TransMembrane:3 (o6-31i43-63o75-91i) AKAW2_60063A COG:Q; EggNog:ENOG410PK2E; InterPro:IPR027443,IPR005123; PFAM:PF03171; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_60064A COG:Q; EggNog:ENOG410PK2E; InterPro:IPR026992,IPR027443; PFAM:PF14226 AKAW2_60065S COG:M; EggNog:ENOG410PKKZ; InterPro:IPR002110,IPR036770,IPR020683; PFAM:PF12796,PF00023,PF13637,PF13606; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_60066A COG:Q; EggNog:ENOG410PFZM; InterPro:IPR036866,IPR029229,IPR036527,IPR044097, IPR038536,IPR001279,IPR029228; PFAM:PF14864,PF14863,PF00753; go_function: GO:0018741 - alkyl sulfatase activity [Evidence IEA]; go_function: GO:0046983 - protein dimerization activity [Evidence IEA]; go_process: GO:0018909 - dodecyl sulfate metabolic process [Evidence IEA] AKAW2_60067S InterPro:IPR036249,IPR013766; PFAM:PF00085 AKAW2_60068A COG:S; EggNog:ENOG410QDYX; InterPro:IPR036864,IPR021858,IPR001138; PFAM:PF00172; TransMembrane:1 (i186-209o); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_60069A COG:S; EggNog:ENOG410PI2D; TransMembrane:1 (o26-54i) AKAW2_60070A COG:P; EggNog:ENOG410PFZ2; InterPro:IPR004698,IPR003689; PFAM:PF02535; TransMembrane:8 (o38-58i70-90o110-129i198-219o225-246i258-281o301-321i333- 351o); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0005385 - zinc ion transmembrane transporter activity [Evidence IEA]; go_function: GO:0046873 - metal ion transmembrane transporter activity [Evidence IEA]; go_process: GO:0030001 - metal ion transport [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA]; go_process: GO:0071577 - zinc ion transmembrane transport [Evidence IEA] AKAW2_60071S CAZy:PL1; COG:G; EggNog:ENOG410PKQN; InterPro:IPR012334,IPR002022,IPR011050; PFAM:PF00544; SECRETED:SignalP(1-23) AKAW2_60072S COG:L; EggNog:ENOG410PGEC; InterPro:IPR012337,IPR025687,IPR036397,IPR043502, IPR017964,IPR042087,IPR006133,IPR006172,IPR023211, IPR006134; PFAM:PF03104,PF14260,PF00136; go_function: GO:0000166 - nucleotide binding [Evidence IEA]; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0003887 - DNA-directed DNA polymerase activity [Evidence IEA] AKAW2_60073S COG:S; EggNog:ENOG410PNHN; InterPro:IPR027417 AKAW2_60075S COG:E; EggNog:ENOG410PIBX; InterPro:IPR004840,IPR004841; PFAM:PF13520,PF00324; TransMembrane:12 (i59-79o85-112i124-146o158-179i191-211o246-267i287- 306o340-365i385-404o416-440i461-481o493-512i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_process: GO:0006865 - amino acid transport [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_60076A COG:E; EggNog:ENOG410QE7V; InterPro:IPR036589,IPR003726; PFAM:PF02574 AKAW2_60077S COG:S; EggNog:ENOG410Q22F AKAW2_60078A COG:S; EggNog:ENOG410PQPA; InterPro:IPR013087 AKAW2_60079A COG:E; EggNog:ENOG410PP37; InterPro:IPR003712,IPR036581,IPR010982,IPR001387, IPR008076; PFAM:PF02560; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008824 - cyanate hydratase activity [Evidence IEA]; go_process: GO:0009439 - cyanate metabolic process [Evidence IEA] AKAW2_60080A COG:S; EggNog:ENOG410PUSJ; InterPro:IPR036864; TransMembrane:1 (o432-453i); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_60081S COG:S; EggNog:ENOG410PJXJ; InterPro:IPR007568; PFAM:PF04479; TransMembrane:7 (n7-15c20/21o30-50i57-76o88-115i127-148o168-190i214- 232o252-276i); go_component: GO:0016021 - integral component of membrane [Evidence IEA] AKAW2_60082S COG:S; EggNog:ENOG410PRMF; InterPro:IPR036236,IPR007219,IPR013087; PFAM:PF13912,PF04082,PF00096,PF12874; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA] AKAW2_60083S COG:C,H; EggNog:ENOG410PG2K; InterPro:IPR036188,IPR002938,IPR036249,IPR038220, IPR012941; PFAM:PF07976,PF01494; go_function: GO:0071949 - FAD binding [Evidence IEA] AKAW2_60084S COG:I; EggNog:ENOG410PHW4; InterPro:IPR016555,IPR015679,IPR001736; PFAM:PF00614; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0004630 - phospholipase D activity [Evidence IEA]; go_process: GO:0006654 - phosphatidic acid biosynthetic process [Evidence IEA]; go_process: GO:0048017 - inositol lipid-mediated signaling [Evidence IEA] AKAW2_60085A COG:H; EggNog:ENOG410PVGX; InterPro:IPR008949,IPR000092; PFAM:PF00348; go_process: GO:0008299 - isoprenoid biosynthetic process [Evidence IEA] AKAW2_60086A COG:V; EggNog:ENOG410PV77; InterPro:IPR001466,IPR012338,IPR021860; MEROPS:MER0026262; PFAM:PF11954,PF00144 AKAW2_60087S COG:S; EggNog:ENOG410PGMK; InterPro:IPR033379,IPR000560,IPR029033; PFAM:PF00328 AKAW2_60088A COG:S; EggNog:ENOG410PGYV; InterPro:IPR013877,IPR040347; PFAM:PF08568; go_process: GO:0034599 - cellular response to oxidative stress [Evidence IEA] AKAW2_60090A COG:S; EggNog:ENOG410PJFN; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; TransMembrane:1 (o539-559i); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_60089S COG:S; EggNog:ENOG410PH44; InterPro:IPR001077,IPR036388,IPR016461,IPR029063, IPR036390; PFAM:PF00891; go_function: GO:0008168 - methyltransferase activity [Evidence IEA]; go_function: GO:0008171 - O-methyltransferase activity [Evidence IEA] AKAW2_60091S COG:S; EggNog:ENOG410PQT1; InterPro:IPR000026,IPR016191; PFAM:PF00545; SECRETED:SignalP(1-20); go_function: GO:0003723 - RNA binding [Evidence IEA]; go_function: GO:0004521 - endoribonuclease activity [Evidence IEA]; go_function: GO:0004540 - ribonuclease activity [Evidence IEA] AKAW2_60092A COG:S; EggNog:ENOG410PJMX; InterPro:IPR007219; PFAM:PF04082; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA] AKAW2_60093S COG:S; EggNog:ENOG410PXTY; InterPro:IPR024512; PFAM:PF11779; TransMembrane:1 (o84-105i) AKAW2_60094S COG:T; EggNog:ENOG410PH15; InterPro:IPR022764,IPR035952,IPR002610; MEROPS:MER0094384; PFAM:PF01694; TransMembrane:7 (i131-151o245-269i281-302o314-331i338-357o363-380i455- 477o); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0004252 - serine-type endopeptidase activity [Evidence IEA]; go_process: GO:0006508 - proteolysis [Evidence IEA] AKAW2_60095S COG:O; EggNog:ENOG410PH9G; InterPro:IPR001594; PFAM:PF01529; TransMembrane:4 (i28-53o73-92i177-200o220-240i); go_function: GO:0016409 - palmitoyltransferase activity [Evidence IEA] AKAW2_60096S COG:O; EggNog:ENOG410PM4H; InterPro:IPR016135,IPR000608; PFAM:PF00179; TransMembrane:1 (o253-270i) AKAW2_60097A COG:K; EggNog:ENOG410PK3N; InterPro:IPR007309,IPR035625 AKAW2_60098S COG:S; EggNog:ENOG410PN83; TransMembrane:6 (i28-53o59-78i99-122o128-150i218-239o245-266i) AKAW2_60099A BUSCO:EOG09262SWJ; COG:S; EggNog:ENOG410PHK6; InterPro:IPR008576,IPR029063; PFAM:PF05891,PF08241,PF13649; go_function: GO:0008168 - methyltransferase activity [Evidence IEA]; go_process: GO:0006480 - N-terminal protein amino acid methylation [Evidence IEA] AKAW2_60100S COG:S; EggNog:ENOG410PJG5; InterPro:IPR001214; PFAM:PF00856; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_60101A COG:O; EggNog:ENOG410PGQY; InterPro:IPR019443,IPR019441,IPR019409,IPR019415, IPR019449,IPR019439; PFAM:PF10347,PF10344,PF10305,PF10359,PF10293, PF10351 AKAW2_60102A COG:S; EggNog:ENOG410PQ5U; InterPro:IPR001834,IPR001433,IPR017938,IPR001709, IPR039261; PFAM:PF00175; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_60103A COG:C,H; EggNog:ENOG410PJFC AKAW2_60104S COG:A; EggNog:ENOG410PJ4G; InterPro:IPR000504,IPR012677,IPR035979; PFAM:PF00076; go_function: GO:0003676 - nucleic acid binding [Evidence IEA] AKAW2_60105S COG:U; EggNog:ENOG410PUWD; InterPro:IPR020846,IPR001958,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:11 (o27-51i72-92o98-119i131-148o160-182i189-208o279-305i317- 337o349-368i380-401o454-477i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_60106S COG:S; EggNog:ENOG410PR27; InterPro:IPR040351,IPR009449; PFAM:PF06428; go_function: GO:0005085 - guanyl-nucleotide exchange factor activity [Evidence IEA] AKAW2_60107S COG:S; EggNog:ENOG410PJSM; InterPro:IPR004104,IPR000683,IPR036291; PFAM:PF01408; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA] AKAW2_60108A COG:M; EggNog:ENOG410Q18J; InterPro:IPR002110,IPR027417,IPR007111,IPR036770, IPR020683; PFAM:PF13857,PF05729,PF12796,PF00023,PF13637, PF13606; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_60109S COG:J; EggNog:ENOG410PNPG; InterPro:IPR036351,IPR001515; PFAM:PF01655; go_component: GO:0005840 - ribosome [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_process: GO:0006412 - translation [Evidence IEA] AKAW2_60110A COG:A; EggNog:ENOG410PHG6; InterPro:IPR020103,IPR006224,IPR006225,IPR002942, IPR006145; PFAM:PF00849; go_function: GO:0003723 - RNA binding [Evidence IEA]; go_function: GO:0009982 - pseudouridine synthase activity [Evidence IEA]; go_process: GO:0001522 - pseudouridine synthesis [Evidence IEA]; go_process: GO:0009451 - RNA modification [Evidence IEA] AKAW2_60111A COG:S; EggNog:ENOG410Q551; InterPro:IPR003615; PFAM:PF13391 AKAW2_60113S COG:T; EggNog:ENOG410PUS4; InterPro:IPR000719,IPR011009; PFAM:PF00069; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_60114S COG:S; EggNog:ENOG410PPWV; InterPro:IPR029069,IPR006683; PFAM:PF03061 AKAW2_60115A COG:S; EggNog:ENOG410Q076 AKAW2_60116A COG:E; EggNog:ENOG410PIS1; InterPro:IPR020558,IPR000581,IPR037237,IPR042096; PFAM:PF00920; go_function: GO:0003824 - catalytic activity [Evidence IEA] AKAW2_60117A COG:O; EggNog:ENOG410PJYM; InterPro:IPR008971,IPR002939,IPR001623,IPR036869, IPR012724,IPR001305,IPR036410,IPR018253; PFAM:PF00684,PF00226,PF01556; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0031072 - heat shock protein binding [Evidence IEA]; go_function: GO:0051082 - unfolded protein binding [Evidence IEA]; go_process: GO:0006457 - protein folding [Evidence IEA]; go_process: GO:0009408 - response to heat [Evidence IEA] AKAW2_60118S COG:J; EggNog:ENOG410PH8U; InterPro:IPR020058,IPR014729,IPR000924; PFAM:PF00749; go_function: GO:0000166 - nucleotide binding [Evidence IEA]; go_function: GO:0004812 - aminoacyl-tRNA ligase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0043039 - tRNA aminoacylation [Evidence IEA] AKAW2_60119A BUSCO:EOG092628LW; COG:D,Z; EggNog:ENOG410PI9Y; InterPro:IPR007145; PFAM:PF03999; go_function: GO:0008017 - microtubule binding [Evidence IEA]; go_process: GO:0000226 - microtubule cytoskeleton organization [Evidence IEA] AKAW2_60120S BUSCO:EOG09263RDD; COG:O; EggNog:ENOG410PIAJ; InterPro:IPR037740,IPR037518,IPR040961,IPR000555; MEROPS:MER0122119; PFAM:PF18323,PF01398; go_component: GO:0008180 - COP9 signalosome [Evidence IEA]; go_function: GO:0004222 - metalloendopeptidase activity [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_function: GO:0008237 - metallopeptidase activity [Evidence IEA]; go_function: GO:0070122 - isopeptidase activity [Evidence IEA] AKAW2_60121A COG:T; EggNog:ENOG410PGVB; InterPro:IPR000651,IPR036964,IPR019804,IPR023578, IPR036028,IPR008937,IPR001895,IPR001452; PFAM:PF14604,PF00018,PF00617,PF07653,PF00618; go_function: GO:0005085 - guanyl-nucleotide exchange factor activity [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0007264 - small GTPase mediated signal transduction [Evidence IEA] AKAW2_60123S COG:K; EggNog:ENOG410PGSQ; InterPro:IPR036236,IPR013087,IPR007219; PFAM:PF04082; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA] AKAW2_60124S COG:F; EggNog:ENOG410PIZM; InterPro:IPR029057,IPR000836; PFAM:PF14681; go_process: GO:0009116 - nucleoside metabolic process [Evidence IEA] AKAW2_60125A COG:S; EggNog:ENOG410PZCP; TransMembrane:1 (o34-54i) AKAW2_60126A COG:O; EggNog:ENOG410Q1WV; SECRETED:SignalP(1-20); TransMembrane:1 (n5-16c20/21o113-130i) AKAW2_60127A COG:K; EggNog:ENOG410PTSM; InterPro:IPR007811; PFAM:PF05132; go_component: GO:0005666 - RNA polymerase III complex [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_process: GO:0006383 - transcription by RNA polymerase III [Evidence IEA] AKAW2_60128A TransMembrane:1 (i44-64o) AKAW2_60129A COG:S; EggNog:ENOG410PG1A; InterPro:IPR001138; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_60130S COG:D; EggNog:ENOG410PGIE; InterPro:IPR036915,IPR006671,IPR004367,IPR039361, IPR013763; PFAM:PF02984,PF00134 AKAW2_60131A COG:A; EggNog:ENOG410PI46; InterPro:IPR011709,IPR009060,IPR016135,IPR027417, IPR007502,IPR015940,IPR014001,IPR001650,IPR011545, IPR006575; PFAM:PF04408,PF00270,PF07717,PF05773,PF00271; TransMembrane:1 (o1042-1064i); go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0004386 - helicase activity [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA] AKAW2_60132S COG:S; EggNog:ENOG410PNGU; InterPro:IPR001310,IPR026963,IPR032566,IPR036265; PFAM:PF11969,PF01230,PF16278; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0033699 - DNA 5'-adenosine monophosphate hydrolase activity [Evidence IEA]; go_process: GO:0006281 - DNA repair [Evidence IEA] AKAW2_60133A COG:U; EggNog:ENOG410PP6Y; InterPro:IPR005595; PFAM:PF03896; TransMembrane:4 (i21-41o53-71i83-103o249-270i); go_component: GO:0005789 - endoplasmic reticulum membrane [Evidence IEA] AKAW2_60134S COG:S; EggNog:ENOG410PNNW AKAW2_60135A COG:S; EggNog:ENOG410PWQN; InterPro:IPR028389,IPR011564,IPR012340,IPR032042; PFAM:PF02765,PF16686; go_component: GO:0000784 - nuclear chromosome, telomeric region [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0043047 - single-stranded telomeric DNA binding [Evidence IEA]; go_process: GO:0000723 - telomere maintenance [Evidence IEA] AKAW2_60136S BUSCO:EOG09261OSU; COG:U; EggNog:ENOG410PI6Q; InterPro:IPR036975,IPR016024,IPR011989,IPR000225, IPR024931,IPR032413,IPR002652; PFAM:PF13513,PF02985,PF13646,PF16186,PF00514, PF01749; go_component: GO:0005737 - cytoplasm [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_function: GO:0061608 - nuclear import signal receptor activity [Evidence IEA]; go_process: GO:0006606 - protein import into nucleus [Evidence IEA] AKAW2_60137A BUSCO:EOG09260R84; COG:D; EggNog:ENOG410PHYP; InterPro:IPR013721,IPR016024,IPR039662,IPR020839; PFAM:PF08514 AKAW2_60138S COG:O; EggNog:ENOG410PJ2R; InterPro:IPR002669; PFAM:PF01774; go_function: GO:0016151 - nickel cation binding [Evidence IEA]; go_process: GO:0006807 - nitrogen compound metabolic process [Evidence IEA] AKAW2_60139A COG:S; EggNog:ENOG410PITV; InterPro:IPR017946; TransMembrane:1 (i122-150o); go_function: GO:0008081 - phosphoric diester hydrolase activity [Evidence IEA]; go_process: GO:0006629 - lipid metabolic process [Evidence IEA] AKAW2_60141S COG:S; EggNog:ENOG410PPXZ; InterPro:IPR038871 AKAW2_60140A BUSCO:EOG092603YJ; COG:A; EggNog:ENOG410PG56; InterPro:IPR011990,IPR022967,IPR003029,IPR003107, IPR012340; PFAM:PF00575; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0006396 - RNA processing [Evidence IEA] AKAW2_60142S COG:S; EggNog:ENOG410PIAA; InterPro:IPR036322,IPR015943,IPR019775,IPR001680, IPR017986; PFAM:PF00400; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_60143A COG:O; EggNog:ENOG410PHQZ; InterPro:IPR002423,IPR027410,IPR027413,IPR017998, IPR002194,IPR012715,IPR027409; PFAM:PF00118; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0051082 - unfolded protein binding [Evidence IEA]; go_process: GO:0006457 - protein folding [Evidence IEA] AKAW2_60144A COG:S; EggNog:ENOG410PXDD AKAW2_60146A COG:J; EggNog:ENOG410PIBF; InterPro:IPR020568,IPR001247; PFAM:PF01138 AKAW2_60147A BUSCO:EOG09260EZT; COG:I; EggNog:ENOG410PFFD; InterPro:IPR007318,IPR016219; PFAM:PF04191; TransMembrane:10 (i84-103o109-131i200-220o226-245i304-322o391-412i419- 442o473-492i504-525o567-594i); go_function: GO:0004608 - phosphatidylethanolamine N-methyltransferase activity [Evidence IEA]; go_process: GO:0006644 - phospholipid metabolic process [Evidence IEA] AKAW2_60148S COG:D; EggNog:ENOG410PHVZ; InterPro:IPR019591,IPR027417,IPR033756,IPR028601, IPR000808; PFAM:PF10609,PF01656; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0051536 - iron-sulfur cluster binding [Evidence IEA]; go_function: GO:0051539 - 4 iron, 4 sulfur cluster binding [Evidence IEA]; go_process: GO:0016226 - iron-sulfur cluster assembly [Evidence IEA] AKAW2_60149S COG:O; EggNog:ENOG410PHZY; InterPro:IPR033121,IPR021109,IPR001461,IPR034163; MEROPS:MER0090757; PFAM:PF00026; SECRETED:SignalP(1-19); go_function: GO:0004190 - aspartic-type endopeptidase activity [Evidence IEA]; go_process: GO:0006508 - proteolysis [Evidence IEA] AKAW2_60150S BUSCO:EOG09263JFQ; COG:J; EggNog:ENOG410PIC3; InterPro:IPR002547,IPR012340,IPR036282; PFAM:PF01588; go_function: GO:0000049 - tRNA binding [Evidence IEA] AKAW2_60151S COG:Q; EggNog:ENOG410PFVV; InterPro:IPR013154,IPR013149,IPR002328,IPR036291, IPR011032,IPR020843; PFAM:PF00107,PF08240,PF16912; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_60152S COG:Q; EggNog:ENOG410Q28W; InterPro:IPR036291,IPR002347; PFAM:PF08659,PF00106; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_60153S CAZy:GT62; COG:G; EggNog:ENOG410PHYH; InterPro:IPR029044; PFAM:PF03452; TransMembrane:1 (i49-71o) AKAW2_60154S COG:D; EggNog:ENOG410PSDP; InterPro:IPR019128; PFAM:PF09724; go_component: GO:0031390 - Ctf18 RFC-like complex [Evidence IEA]; go_process: GO:0007064 - mitotic sister chromatid cohesion [Evidence IEA] AKAW2_60155A COG:S; EggNog:ENOG410PJ7F; InterPro:IPR000182,IPR016181; PFAM:PF13508,PF00583; go_function: GO:0008080 - N-acetyltransferase activity [Evidence IEA] AKAW2_60156S COG:O; EggNog:ENOG410PIRM; InterPro:IPR002867,IPR044066; PFAM:PF01485 AKAW2_60157A COG:D; EggNog:ENOG410PQU7; InterPro:IPR036570,IPR003511; PFAM:PF02301 AKAW2_60158S BUSCO:EOG09260IU8; COG:U,Y; EggNog:ENOG410PH26; InterPro:IPR001494,IPR016024,IPR011989; PFAM:PF03810; go_function: GO:0008536 - Ran GTPase binding [Evidence IEA]; go_process: GO:0006886 - intracellular protein transport [Evidence IEA] AKAW2_60159S COG:S; EggNog:ENOG410PH04; InterPro:IPR029063; PFAM:PF13649,PF13489,PF08242,PF08241,PF13847 AKAW2_60160A COG:S; EggNog:ENOG410PJ9F; InterPro:IPR008775; PFAM:PF05721 AKAW2_60161S COG:S; EggNog:ENOG410PFTA; InterPro:IPR010816; PFAM:PF07217; SECRETED:SignalP(1-28) AKAW2_60162A COG:O; EggNog:ENOG410QE1X; InterPro:IPR001841,IPR008974,IPR027370,IPR017907, IPR001293,IPR043211,IPR013083; PFAM:PF00097,PF13445,PF02176; go_function: GO:0005515 - protein binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA] AKAW2_60163S COG:U; EggNog:ENOG410PJY6; InterPro:IPR000727; PFAM:PF05739; TransMembrane:1 (o240-259i) AKAW2_60164A COG:S; EggNog:ENOG410PS54 AKAW2_60165A COG:S; EggNog:ENOG410PQ9V; InterPro:IPR027915; PFAM:PF14618 AKAW2_60166A BUSCO:EOG09262K8C; COG:K; EggNog:ENOG410PI7B; InterPro:IPR036915,IPR028367,IPR043198,IPR006671, IPR013763; PFAM:PF00134; TransMembrane:1 (o188-206i); go_component: GO:0016592 - mediator complex [Evidence IEA]; go_function: GO:0016538 - cyclin-dependent protein serine/threonine kinase regulator activity [Evidence IEA]; go_process: GO:0006357 - regulation of transcription by RNA polymerase II [Evidence IEA] AKAW2_60167S BUSCO:EOG09262PZ9; COG:C; EggNog:ENOG410PHDS; InterPro:IPR011992,IPR023395,IPR018108,IPR002048, IPR018247,IPR002067; PFAM:PF00036,PF13405,PF00153,PF13202,PF13499, PF13833; go_function: GO:0005509 - calcium ion binding [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_60168A COG:O; EggNog:ENOG410PFDC; InterPro:IPR036249,IPR040079,IPR036282,IPR010987, IPR004045,IPR016639; PFAM:PF13409,PF00043,PF13410; go_function: GO:0004364 - glutathione transferase activity [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0006749 - glutathione metabolic process [Evidence IEA] AKAW2_60169A BUSCO:EOG09260ERO; COG:O; EggNog:ENOG410PFZC; InterPro:IPR019572,IPR042302,IPR035985,IPR018965, IPR000594,IPR042449,IPR038252,IPR018075,IPR033127, IPR032418,IPR042063,IPR000011,IPR032420; PFAM:PF16190,PF16191,PF10585,PF09358,PF00899; go_function: GO:0008641 - ubiquitin-like modifier activating enzyme activity [Evidence IEA]; go_process: GO:0006464 - cellular protein modification process [Evidence IEA] AKAW2_60170S COG:Z; EggNog:ENOG410PKU6; InterPro:IPR007259,IPR041470,IPR040457; PFAM:PF04130,PF17681; go_component: GO:0000922 - spindle pole [Evidence IEA]; go_component: GO:0005815 - microtubule organizing center [Evidence IEA]; go_function: GO:0043015 - gamma-tubulin binding [Evidence IEA]; go_process: GO:0000226 - microtubule cytoskeleton organization [Evidence IEA]; go_process: GO:0007020 - microtubule nucleation [Evidence IEA] AKAW2_60172S COG:Q; EggNog:ENOG410PIXZ; InterPro:IPR002347,IPR036291,IPR020904; PFAM:PF00106,PF13561,PF08659,PF01370; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_60173A COG:G; EggNog:ENOG410QDJ0; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i104-123o143-162i169-188o194-218i230-250o262-284i342- 366o378-395i407-428o440-462i474-496o502-528i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_60174A COG:S; EggNog:ENOG410PYR0 AKAW2_60175A COG:S; EggNog:ENOG410PP7K; InterPro:IPR004911; PFAM:PF03227; TransMembrane:1 (i34-54o) AKAW2_60176S COG:G; EggNog:ENOG410PHN5; InterPro:IPR001312,IPR022673,IPR022672,IPR043129; PFAM:PF00349,PF03727; go_function: GO:0004396 - hexokinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0005536 - glucose binding [Evidence IEA]; go_function: GO:0016773 - phosphotransferase activity, alcohol group as acceptor [Evidence IEA]; go_process: GO:0001678 - cellular glucose homeostasis [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_60177A COG:S; EggNog:ENOG410PTJA; SECRETED:SignalP(1-15) AKAW2_60178S COG:K; EggNog:ENOG410PPMK; InterPro:IPR015872,IPR009083,IPR003194; PFAM:PF02268; go_component: GO:0005672 - transcription factor TFIIA complex [Evidence IEA]; go_process: GO:0006367 - transcription initiation from RNA polymerase II promoter [Evidence IEA] AKAW2_60179S COG:S; EggNog:ENOG410PTZS AKAW2_60181A COG:C; EggNog:ENOG410PFJV; InterPro:IPR015590,IPR029510,IPR016161,IPR016162, IPR016163; PFAM:PF00171; TransMembrane:1 (i131-154o); go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0016620 - oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_60182A COG:F; EggNog:ENOG410PGJ9; InterPro:IPR016187,IPR024775,IPR005532,IPR042095, IPR019257,IPR017805; PFAM:PF10017,PF03781,PF12867 AKAW2_60184S InterPro:IPR011990; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_60185A COG:S; EggNog:ENOG410PFG3; InterPro:IPR002794; PFAM:PF01940; TransMembrane:4 (n4-14c19/20o29-55i181-201o217-239i338-359o); go_component: GO:0016021 - integral component of membrane [Evidence IEA] AKAW2_60186S COG:S; EggNog:ENOG410PS93; TransMembrane:4 (i7-31o43-62i82-106o184-206i) AKAW2_60187S COG:S; EggNog:ENOG410Q27X; InterPro:IPR036864,IPR021858,IPR001138; PFAM:PF00172,PF11951; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_60189A COG:S; EggNog:ENOG410PXXD AKAW2_60190A COG:S; EggNog:ENOG410PHTW; InterPro:IPR007197,IPR040085,IPR016431,IPR013785; PFAM:PF04055; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0051536 - iron-sulfur cluster binding [Evidence IEA] AKAW2_60191A COG:K; EggNog:ENOG410PMTG; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; TransMembrane:1 (o844-864i); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_60192A COG:K; EggNog:ENOG410PJAJ; InterPro:IPR002092,IPR037159,IPR029262,IPR043502; PFAM:PF14700,PF00940; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0003899 - DNA-directed 5'-3' RNA polymerase activity [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA] AKAW2_60193A COG:S; EggNog:ENOG410PQ1V; InterPro:IPR006886; PFAM:PF04801; go_component: GO:0005634 - nucleus [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA] AKAW2_60194A BUSCO:EOG0926047G; COG:P; EggNog:ENOG410PFG9; InterPro:IPR029061,IPR002880,IPR005117,IPR001094, IPR006066,IPR006067,IPR029039,IPR036136,IPR008254, IPR009014; PFAM:PF01077,PF00258,PF03460; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0010181 - FMN binding [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_function: GO:0051536 - iron-sulfur cluster binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_60196A COG:S; EggNog:ENOG410PMAG; InterPro:IPR013862; PFAM:PF08552; TransMembrane:4 (i16-38o58-78i90-114o173-194i); go_function: GO:0070917 - inositol phosphoceramide synthase regulator activity [Evidence IEA]; go_process: GO:0006673 - inositol phosphoceramide metabolic process [Evidence IEA] AKAW2_60197A BUSCO:EOG09264JHE; COG:U; EggNog:ENOG410PI1P; InterPro:IPR005225,IPR001806,IPR027417; PFAM:PF04670,PF00025,PF08477,PF00071,PF01926, PF09439; go_function: GO:0003924 - GTPase activity [Evidence IEA]; go_function: GO:0005525 - GTP binding [Evidence IEA] AKAW2_60198S BUSCO:EOG09265G5C; COG:C; EggNog:ENOG410PGFJ; InterPro:IPR035921,IPR000245,IPR002379; PFAM:PF00137; TransMembrane:5 (i7-23o43-65i86-108o128-153i165-190o); go_component: GO:0033177 - proton-transporting two-sector ATPase complex, proton-transporting domain [Evidence IEA]; go_component: GO:0033179 - proton-transporting V-type ATPase, V0 domain [Evidence IEA]; go_function: GO:0015078 - proton transmembrane transporter activity [Evidence IEA]; go_process: GO:1902600 - proton transmembrane transport [Evidence IEA] AKAW2_60199S COG:H; EggNog:ENOG410PIEQ; InterPro:IPR005111,IPR005110,IPR036425,IPR036688, IPR008284,IPR036135,IPR001453,IPR038987; PFAM:PF03453,PF03454,PF00994; TransMembrane:1 (o578-601i); go_process: GO:0006777 - Mo-molybdopterin cofactor biosynthetic process [Evidence IEA]; go_process: GO:0032324 - molybdopterin cofactor biosynthetic process [Evidence IEA] AKAW2_60200A COG:I,U; EggNog:ENOG410PH35; InterPro:IPR004177,IPR029058; go_function: GO:0046872 - metal ion binding [Evidence IEA] AKAW2_60201A COG:S; EggNog:ENOG410PRRP AKAW2_60202S BUSCO:EOG09264X31; COG:A; EggNog:ENOG410PP1C; InterPro:IPR008584; PFAM:PF05907 AKAW2_60203S COG:A; EggNog:ENOG410PS3G; InterPro:IPR016487,IPR010920,IPR034100,IPR001163; PFAM:PF01423; go_component: GO:0005681 - spliceosomal complex [Evidence IEA]; go_component: GO:0005732 - small nucleolar ribonucleoprotein complex [Evidence IEA]; go_process: GO:0000387 - spliceosomal snRNP assembly [Evidence IEA]; go_process: GO:0000398 - mRNA splicing, via spliceosome [Evidence IEA] AKAW2_60204A SECRETED:SignalP(1-18) AKAW2_60205A InterPro:IPR025700,IPR036188 AKAW2_60206A COG:T; EggNog:ENOG410PJP7; InterPro:IPR000719,IPR011009; PFAM:PF07714,PF00069; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_60207S COG:S; EggNog:ENOG410PXJ0 AKAW2_60208S COG:A; EggNog:ENOG410PVDN; InterPro:IPR036322,IPR027417,IPR007111,IPR015943, IPR019775,IPR001680,IPR031359; PFAM:PF05729,PF00400,PF17100; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_60209S COG:S; EggNog:ENOG410PWV9 AKAW2_60210S COG:E; EggNog:ENOG410PHHD; InterPro:IPR013057; PFAM:PF01490; TransMembrane:7 (o47-67i74-95o125-145i157-176o182-204i225-246o258-278i) AKAW2_60211S COG:E; EggNog:ENOG410Q1Y5; InterPro:IPR013057; TransMembrane:3 (i7-27o39-60i72-95o) AKAW2_60212S COG:G; EggNog:ENOG410PFTW; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i78-95o115-134i146-163o175-196i203-226o238-264i311- 328o348-369i390-409o421-442i454-477o483-505i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_60214S COG:S; EggNog:ENOG410PTJX; InterPro:IPR032805; PFAM:PF13813; TransMembrane:5 (o173-193i205-224o299-317i329-349o364-382i) AKAW2_60215S COG:G,M; EggNog:ENOG410PW89; InterPro:IPR036291,IPR008030; PFAM:PF13460,PF05368 AKAW2_60216A COG:G; EggNog:ENOG410PFSN; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i78-99o119-140i147-166o178-199i211-233o239-262i316- 335o355-377i398-417o423-446i458-479o491-512i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_60217S COG:Q; EggNog:ENOG410Q88T; InterPro:IPR036291,IPR002347; PFAM:PF08659,PF00106,PF13561; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_60218A COG:G; EggNog:ENOG410PGYF; InterPro:IPR005829,IPR005828,IPR003663,IPR036259, IPR020846; PFAM:PF00083,PF07690; TransMembrane:12 (i39-59o100-119i126-145o151-173i185-208o220-237i300- 323o343-363i370-391o397-423i435-453o465-486i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_60219A COG:O; EggNog:ENOG410PQI6; InterPro:IPR008978,IPR002068; PFAM:PF00011,PF17886 AKAW2_60220A COG:S; EggNog:ENOG410PYBH AKAW2_60221S CAZy:GH28; COG:G; EggNog:ENOG410PFRD; InterPro:IPR000743,IPR012334,IPR006626,IPR011050; PFAM:PF00295; SECRETED:SignalP(1-21); go_function: GO:0004650 - polygalacturonase activity [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_60222A COG:S; EggNog:ENOG410PV89; InterPro:IPR036291,IPR008030; PFAM:PF13460,PF05368 AKAW2_60223A CAZy:GH16; COG:G; EggNog:ENOG410PJVM; InterPro:IPR000757,IPR013320; PFAM:PF00722; SECRETED:SignalP(1-19); TransMembrane:1 (n7-14c19/20o297-319i); go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_60224A COG:I; EggNog:ENOG410PKI5; InterPro:IPR022237,IPR003817; PFAM:PF12588,PF02666; go_function: GO:0004609 - phosphatidylserine decarboxylase activity [Evidence IEA]; go_process: GO:0008654 - phospholipid biosynthetic process [Evidence IEA] AKAW2_60225A COG:S; EggNog:ENOG410PWP7; InterPro:IPR014710,IPR011051,IPR013096; PFAM:PF07883,PF00190 AKAW2_60226A COG:S; EggNog:ENOG410PQ85; InterPro:IPR036864,IPR021858,IPR001138; PFAM:PF00172,PF11951; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_60227S COG:Q; EggNog:ENOG410PKXW; InterPro:IPR017871,IPR027417,IPR003593,IPR011527, IPR003439,IPR036640; PFAM:PF00005,PF00664; TransMembrane:11 (i111-128o134-153i221-245o336-354i707-726o785-812i864- 884o890-910i922-942o972-992i999-1020o); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA]; go_function: GO:0042626 - ATPase-coupled transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_60228A COG:Q; EggNog:ENOG410PWUG; InterPro:IPR001128,IPR036396; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_60229S COG:S; EggNog:ENOG410PJC9; InterPro:IPR008949; TransMembrane:1 (o294-317i) AKAW2_60230A COG:S; EggNog:ENOG410Q013 AKAW2_60231A COG:S; EggNog:ENOG410PZMN AKAW2_60233A COG:S; EggNog:ENOG410PIYI; InterPro:IPR011118,IPR029058; PFAM:PF07519; SECRETED:SignalP(1-23) AKAW2_60234S CAZy:CE10; COG:I; EggNog:ENOG410Q4K2; InterPro:IPR019819,IPR019826,IPR002018,IPR029058; MEROPS:MER0030934; PFAM:PF00135; SECRETED:SignalP(1-18) AKAW2_60235A COG:Q; EggNog:ENOG410PPD6; InterPro:IPR036291,IPR002347; PFAM:PF13561; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_60236A InterPro:IPR035923 AKAW2_60237S COG:S; EggNog:ENOG410PQZ2; InterPro:IPR011042; SECRETED:SignalP(1-21) AKAW2_60238S COG:G; EggNog:ENOG410PMGT; InterPro:IPR012083,IPR017850,IPR000917,IPR024607; PFAM:PF00884; SECRETED:SignalP(1-19); go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0004065 - arylsulfatase activity [Evidence IEA]; go_function: GO:0008484 - sulfuric ester hydrolase activity [Evidence IEA]; go_process: GO:0018958 - phenol-containing compound metabolic process [Evidence IEA] AKAW2_60239S COG:I; EggNog:ENOG410PPGE; InterPro:IPR008901; PFAM:PF05875; TransMembrane:7 (o32-50i62-80o92-110i117-133o139-155i176-194o221-241i); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0016811 - hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [Evidence IEA]; go_process: GO:0006672 - ceramide metabolic process [Evidence IEA] AKAW2_60240A COG:A; EggNog:ENOG410PVDN; InterPro:IPR024977,IPR036322,IPR027417,IPR007111, IPR015943,IPR011047,IPR001680,IPR031359,IPR017986; PFAM:PF12894,PF05729,PF00400,PF17100,PF13191; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_60241S COG:Q; EggNog:ENOG410PM5U AKAW2_60242S COG:Q; EggNog:ENOG410PM5U; InterPro:IPR001128,IPR017972,IPR036396; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_60243S COG:S; EggNog:ENOG410PPE5; InterPro:IPR036864,IPR001138; PFAM:PF00172; TransMembrane:3 (o157-177i366-384o396-417i); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_60244A COG:Q; EggNog:ENOG410Q2DQ; InterPro:IPR013968,IPR020806,IPR036736,IPR009081; PFAM:PF00550; go_function: GO:0031177 - phosphopantetheine binding [Evidence IEA] AKAW2_60245S COG:S; EggNog:ENOG410PFE4; InterPro:IPR001138,IPR007219,IPR036864; PFAM:PF04082; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_60246S COG:G; EggNog:ENOG410PJXI; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:14 (i33-51o73-95i102-122o128-149i161-180o192-211i232-258o264- 285i305-329o344-362i367-387o399-421i433-456o508-530i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_60247A COG:V; EggNog:ENOG410PIPX; InterPro:IPR001466,IPR012338; MEROPS:MER0011726; PFAM:PF00144 AKAW2_60248A COG:S; EggNog:ENOG410PRFW; SECRETED:SignalP(1-16) AKAW2_60250A COG:S; EggNog:ENOG410PS5Y AKAW2_60252A COG:S; EggNog:ENOG410PG0P; InterPro:IPR011118 AKAW2_60253A COG:S; EggNog:ENOG410Q1UW; InterPro:IPR006461; PFAM:PF04749 AKAW2_60254A COG:C; EggNog:ENOG410PV9B; InterPro:IPR023210,IPR036812; PFAM:PF00248 AKAW2_60255S COG:S; EggNog:ENOG410PHAA; InterPro:IPR010730; PFAM:PF06985 AKAW2_60256S COG:S; EggNog:ENOG410PVRA; InterPro:IPR029063; PFAM:PF13489,PF08241,PF13649 AKAW2_60257S CAZy:AA9; COG:G; EggNog:ENOG410PWTS; InterPro:IPR000254,IPR035971,IPR005103; PFAM:PF00734,PF03443; SECRETED:SignalP(1-20); go_component: GO:0005576 - extracellular region [Evidence IEA]; go_function: GO:0030248 - cellulose binding [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_60259A COG:U; EggNog:ENOG410PJTM; InterPro:IPR037104,IPR001464,IPR009117,IPR018252, IPR018502; PFAM:PF00191; go_function: GO:0005509 - calcium ion binding [Evidence IEA]; go_function: GO:0005544 - calcium-dependent phospholipid binding [Evidence IEA] AKAW2_60260A CAZy:GT1; COG:C,G; EggNog:ENOG410PK3H; InterPro:IPR002213,IPR004276; go_function: GO:0008194 - UDP-glycosyltransferase activity [Evidence IEA]; go_function: GO:0016758 - transferase activity, transferring hexosyl groups [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA]; go_process: GO:0030259 - lipid glycosylation [Evidence IEA] AKAW2_60261A COG:M; EggNog:ENOG410PM4D; InterPro:IPR033506,IPR002110,IPR030395,IPR017946, IPR036770,IPR020683,IPR004331; PFAM:PF12796,PF00023,PF03009; go_function: GO:0005515 - protein binding [Evidence IEA]; go_function: GO:0008081 - phosphoric diester hydrolase activity [Evidence IEA]; go_function: GO:0047389 - glycerophosphocholine phosphodiesterase activity [Evidence IEA]; go_process: GO:0006629 - lipid metabolic process [Evidence IEA]; go_process: GO:0046475 - glycerophospholipid catabolic process [Evidence IEA] AKAW2_60262S COG:M; EggNog:ENOG410PH05; InterPro:IPR002110,IPR036770,IPR031348,IPR020683; PFAM:PF12796,PF00023,PF17111; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_60263A COG:S; EggNog:ENOG410PX22; InterPro:IPR010730; PFAM:PF06985 AKAW2_60264S CAZy:GT71; COG:S; EggNog:ENOG410PKWN; InterPro:IPR022751,IPR029044; PFAM:PF11051; TransMembrane:1 (i25-45o); go_function: GO:0016757 - transferase activity, transferring glycosyl groups [Evidence IEA]; go_process: GO:0006486 - protein glycosylation [Evidence IEA] AKAW2_60265A CAZy:GH3; COG:G; EggNog:ENOG410PHDM; InterPro:IPR017853,IPR036962,IPR002772,IPR036881, IPR026891,IPR013783,IPR001764; PFAM:PF14310,PF00933,PF01915; SECRETED:SignalP(1-22); go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_60267S COG:S; EggNog:ENOG410Q2CK AKAW2_60268S COG:S; EggNog:ENOG410Q0BQ; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_60269A COG:C; EggNog:ENOG410PG0V; InterPro:IPR023210,IPR036812; PFAM:PF00248 AKAW2_60270S COG:E; EggNog:ENOG410Q2HV; InterPro:IPR010107,IPR002129,IPR015424,IPR015421; PFAM:PF00282,PF00266; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0004351 - glutamate decarboxylase activity [Evidence IEA]; go_function: GO:0016831 - carboxy-lyase activity [Evidence IEA]; go_function: GO:0030170 - pyridoxal phosphate binding [Evidence IEA]; go_process: GO:0006536 - glutamate metabolic process [Evidence IEA]; go_process: GO:0019752 - carboxylic acid metabolic process [Evidence IEA] AKAW2_60271S CAZy:GH71; COG:G; EggNog:ENOG410PJGT; InterPro:IPR005197; PFAM:PF03659; SECRETED:SignalP(1-20); TransMembrane:1 (n4-15c20/21o473-492i); go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_60272S COG:S; EggNog:ENOG410Q1M2 AKAW2_60273S COG:S; EggNog:ENOG410Q2ZX; InterPro:IPR032805; PFAM:PF13813; TransMembrane:8 (o6-26i33-52o58-79i149-168o209-237i293-311o323-348i360- 381o) AKAW2_60274A COG:S; EggNog:ENOG410PIJ9; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_60275A COG:S; EggNog:ENOG410PY1B; InterPro:IPR003807; PFAM:PF02656; TransMembrane:3 (i133-154o174-195i216-236o) AKAW2_60276A COG:S; EggNog:ENOG410PYGA; InterPro:IPR011057,IPR006913; PFAM:PF04828; SECRETED:SignalP(1-20); go_function: GO:0016846 - carbon-sulfur lyase activity [Evidence IEA] AKAW2_60278A COG:S; EggNog:ENOG410PM4A; InterPro:IPR001594,IPR033682; PFAM:PF01529; TransMembrane:4 (i12-32o44-61i139-158o178-199i); go_component: GO:0005789 - endoplasmic reticulum membrane [Evidence IEA]; go_function: GO:0016409 - palmitoyltransferase activity [Evidence IEA]; go_function: GO:0019706 - protein-cysteine S-palmitoyltransferase activity [Evidence IEA] AKAW2_60279S COG:L; EggNog:ENOG410PMDG; InterPro:IPR014762,IPR003594,IPR036890,IPR038973, IPR013507,IPR020568,IPR014721; PFAM:PF01119,PF02518; go_component: GO:0032300 - mismatch repair complex [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA]; go_function: GO:0030983 - mismatched DNA binding [Evidence IEA]; go_process: GO:0006298 - mismatch repair [Evidence IEA] AKAW2_60280S COG:S; EggNog:ENOG410PHDZ; InterPro:IPR010721; PFAM:PF04140,PF06966; TransMembrane:2 (i157-175o187-206i) AKAW2_60281A COG:C; EggNog:ENOG410QE5F; InterPro:IPR036291,IPR029752,IPR006140; go_function: GO:0051287 - NAD binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_60282S COG:S; EggNog:ENOG410PWP1; InterPro:IPR041622; PFAM:PF18142; TransMembrane:2 (i145-170o176-194i) AKAW2_60284S COG:S; EggNog:ENOG410PRKY; InterPro:IPR016181,IPR000182; PFAM:PF13508,PF13527,PF13673,PF00583; TransMembrane:1 (o230-248i); go_function: GO:0008080 - N-acetyltransferase activity [Evidence IEA] AKAW2_60285A COG:G; EggNog:ENOG410PHMS; InterPro:IPR020846,IPR005828,IPR036259; PFAM:PF00083; TransMembrane:12 (i90-111o131-151i158-175o181-201i222-240o286-305i368- 391o424-442i454-470o476-497i509-528o540-558i); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_60287S COG:S; EggNog:ENOG410PHFD; InterPro:IPR036291,IPR016040; PFAM:PF01118 AKAW2_60288A COG:Q; EggNog:ENOG410PU8B; InterPro:IPR013154,IPR013149,IPR002328,IPR036291, IPR011032; PFAM:PF00107,PF08240; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_60289A COG:P; EggNog:ENOG410PFD9; InterPro:IPR002645,IPR001902,IPR018045,IPR036513, IPR011547; PFAM:PF00916,PF01740; TransMembrane:10 (i59-76o82-102i109-125o131-149i161-183o243-262i274- 296o368-384i405-428o462-494i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0008271 - secondary active sulfate transmembrane transporter activity [Evidence IEA]; go_function: GO:0015116 - sulfate transmembrane transporter activity [Evidence IEA]; go_process: GO:0008272 - sulfate transport [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_60290A COG:S; EggNog:ENOG410PVFI; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_60291S COG:G; EggNog:ENOG410Q07H; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690,PF00083; TransMembrane:12 (i85-104o116-140i152-172o178-200i212-235o241-260i310- 336o356-376i396-416o428-449i461-483o489-512i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_60292A CAZy:AA9; COG:S; EggNog:ENOG410PUJ0; InterPro:IPR000254,IPR035971,IPR005103; PFAM:PF00734,PF03443; SECRETED:SignalP(1-20); go_component: GO:0005576 - extracellular region [Evidence IEA]; go_function: GO:0030248 - cellulose binding [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_60293S CAZy:GH11; COG:O; EggNog:ENOG410Q24E; InterPro:IPR001137,IPR013319,IPR033123,IPR013320; PFAM:PF00457; SECRETED:SignalP(1-27); go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_60294A COG:G; EggNog:ENOG410PM1X; InterPro:IPR008928,IPR012341; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_60295A COG:D; EggNog:ENOG410PGS0; InterPro:IPR017441,IPR008271,IPR033701,IPR000719, IPR011009,IPR033695; PFAM:PF07714,PF00069; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_60296S COG:S; EggNog:ENOG410PQ6U; InterPro:IPR010754; PFAM:PF07047; TransMembrane:1 (o129-148i) AKAW2_60298S BUSCO:EOG092608L0; COG:Z; EggNog:ENOG410PGUQ; InterPro:IPR010926,IPR036961,IPR001609,IPR027417, IPR035535,IPR036028,IPR036072,IPR001452; PFAM:PF00018,PF06017,PF07653,PF00063; go_component: GO:0016459 - myosin complex [Evidence IEA]; go_function: GO:0003774 - motor activity [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA] AKAW2_60299A COG:S; EggNog:ENOG410PRYB AKAW2_60300A COG:S; EggNog:ENOG410PJES; InterPro:IPR015943,IPR001680,IPR036322,IPR017986, IPR019775; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_60301S COG:C; EggNog:ENOG410QE5F; InterPro:IPR036291,IPR029752,IPR006140; go_function: GO:0051287 - NAD binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_60304S COG:C; EggNog:ENOG410PN40; InterPro:IPR001155,IPR013785; PFAM:PF00724; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0010181 - FMN binding [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_60303A COG:S; EggNog:ENOG410PW8R; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; TransMembrane:1 (i212-230o); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_60305S COG:S; EggNog:ENOG410PWPH; InterPro:IPR036864,IPR001138; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_60306A COG:Q; EggNog:ENOG410PIVB; InterPro:IPR036291,IPR002347; PFAM:PF00106,PF13561; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_60307S COG:Q; EggNog:ENOG410PUB2; InterPro:IPR001128,IPR002401,IPR036396; PFAM:PF00067; TransMembrane:2 (o12-36i307-330o); go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_60308A COG:Q; EggNog:ENOG410PJI6; InterPro:IPR006680,IPR011059,IPR032466; MEROPS:MER0005900; PFAM:PF01979; go_function: GO:0016787 - hydrolase activity [Evidence IEA]; go_function: GO:0016810 - hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [Evidence IEA] AKAW2_60309S COG:E; EggNog:ENOG410PKRR; InterPro:IPR006439,IPR023198,IPR036412,IPR023214; PFAM:PF13419,PF00702; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_60310A COG:E; EggNog:ENOG410PJ6Z; InterPro:IPR006076,IPR036188; PFAM:PF01266; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_60311S COG:G; EggNog:ENOG410QDI9; InterPro:IPR011701,IPR036259; PFAM:PF07690; TransMembrane:10 (i46-63o87-109i116-135o177-198i210-232o317-337i346- 365o377-397i409-428o440-461i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_60312A COG:S; EggNog:ENOG410PJHC; InterPro:IPR035896,IPR011009,IPR002575; PFAM:PF01636 AKAW2_60313S COG:K; EggNog:ENOG410PJHT; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_60314A COG:Q; EggNog:ENOG410PMQ6; InterPro:IPR001128,IPR002403,IPR017972,IPR036396; PFAM:PF00067; TransMembrane:2 (i27-47o59-80i); go_function: GO:0004497 - monooxygenase activity [Evidence IEA]; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_60315S COG:Q; EggNog:ENOG410PK4R; InterPro:IPR036396; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_60316S COG:Q; EggNog:ENOG410PK4R; InterPro:IPR001128,IPR002403,IPR036396; go_function: GO:0004497 - monooxygenase activity [Evidence IEA]; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_60317S COG:S; EggNog:ENOG410PR9P; TransMembrane:7 (o32-55i67-89o109-131i143-160o187-214i226-246o258-283i) AKAW2_60318S COG:Q; EggNog:ENOG410PJ8G; InterPro:IPR002347,IPR036291,IPR020904; PFAM:PF00106,PF13460,PF13561,PF08659; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_60319A CAZy:AA7; COG:C; EggNog:ENOG410PINF; InterPro:IPR006094,IPR036318,IPR016166,IPR016167, IPR016169; PFAM:PF01565; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_function: GO:0071949 - FAD binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_60320S CAZy:AA7; COG:C; EggNog:ENOG410PINF; InterPro:IPR016166,IPR006094,IPR036318; PFAM:PF01565; SECRETED:SignalP(1-20); go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_function: GO:0071949 - FAD binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_60321A COG:S; EggNog:ENOG410PVKC; InterPro:IPR036291,IPR001509; PFAM:PF01370; go_function: GO:0003824 - catalytic activity [Evidence IEA] AKAW2_60322S COG:Q; EggNog:ENOG410PIQ2; InterPro:IPR013149,IPR036291,IPR011032,IPR020843; PFAM:PF00107,PF13602; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_60323A COG:G; EggNog:ENOG410PMQG; InterPro:IPR005829,IPR005828,IPR003663,IPR036259, IPR020846; PFAM:PF00083,PF07690; TransMembrane:12 (i21-40o74-92i104-121o127-149i161-180o200-218i291-313o333- 351i360-380o400-420i432-449o461-482i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_60324S CAZy:GH33; COG:G; EggNog:ENOG410PJ4H; InterPro:IPR036278,IPR011040; PFAM:PF13088; antiSMASH:Cluster_6.1 AKAW2_60325A antiSMASH:Cluster_6.1 AKAW2_60326A COG:E; EggNog:ENOG410PKAV; InterPro:IPR002220,IPR013785; PFAM:PF00701; antiSMASH:Cluster_6.1; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0016829 - lyase activity [Evidence IEA] AKAW2_60327S COG:S; EggNog:ENOG410PICM; InterPro:IPR036864,IPR001138; PFAM:PF00172; antiSMASH:Cluster_6.1; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_60328A COG:C; EggNog:ENOG410PFM7; InterPro:IPR023210,IPR036812; PFAM:PF00248; SMCOG1039:aldo/keto reductase family oxidoreductase; antiSMASH:Cluster_6.1 AKAW2_60329S COG:S; EggNog:ENOG410Q2IK; antiSMASH:Cluster_6.1 AKAW2_60330S COG:S; EggNog:ENOG410Q2IB; antiSMASH:Cluster_6.1 AKAW2_60331S COG:S; EggNog:ENOG410PRRA; InterPro:IPR001128,IPR036396; TransMembrane:1 (n8-16c20/21o355-376i); antiSMASH:Cluster_6.1; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_60332A COG:S; EggNog:ENOG410PXG5; InterPro:IPR011042; SECRETED:SignalP(1-18); antiSMASH:Cluster_6.1 AKAW2_60333A COG:Q; EggNog:ENOG410PUSX; InterPro:IPR036291,IPR002347; PFAM:PF08659,PF00106,PF13561; SMCOG1001:short-chain dehydrogenase/reductase SDR; antiSMASH:Cluster_6.1; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_60334A COG:Q; EggNog:ENOG410PJA1; InterPro:IPR020806,IPR036736,IPR009081,IPR006162; PFAM:PF00550; antiSMASH:Cluster_6.1; go_function: GO:0031177 - phosphopantetheine binding [Evidence IEA] AKAW2_60335A COG:Q; EggNog:ENOG410PJA1; InterPro:IPR016036,IPR016035,IPR016039,IPR018201, IPR042104,IPR014030,IPR011032,IPR013968,IPR013154, IPR001227,IPR032821,IPR014031,IPR014043,IPR002328, IPR020807,IPR020843,IPR020841,IPR013149,IPR029063, IPR036291,IPR013217; PFAM:PF00109,PF08659,PF13561,PF13489,PF08240, PF02801,PF00698,PF13847,PF13649,PF13602,PF14765,PF00107, PF00106,PF08242,PF08241; SMCOG1022:Beta-ketoacyl synthase; antiSMASH:Cluster_6.1; go_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein] synthase activity [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0016740 - transferase activity [Evidence IEA]; go_function: GO:0016746 - transferase activity, transferring acyl groups [Evidence IEA]; go_process: GO:0006633 - fatty acid biosynthetic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_60336S COG:S; EggNog:ENOG410PXWQ; TransMembrane:5 (o12-33i45-67o97-115i127-150o162-183i); antiSMASH:Cluster_6.1 AKAW2_60337A COG:S; EggNog:ENOG410PSN3; InterPro:IPR023213; antiSMASH:Cluster_6.1 AKAW2_60338A COG:S; EggNog:ENOG410PI6V; antiSMASH:Cluster_6.1 AKAW2_60339S COG:S; EggNog:ENOG410PPZ7; antiSMASH:Cluster_6.1 AKAW2_60340A COG:S; EggNog:ENOG410Q1ZV; antiSMASH:Cluster_6.1 AKAW2_60341S COG:S; EggNog:ENOG410PZ8S; antiSMASH:Cluster_6.1 AKAW2_60342A COG:C; EggNog:ENOG410PICX; InterPro:IPR015590,IPR029510,IPR016161,IPR016162, IPR016163; PFAM:PF00171; SMCOG1017:aldehyde dehydrogenase; antiSMASH:Cluster_6.1; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0016620 - oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_60344S COG:U; EggNog:ENOG410QDYE; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i97-117o137-157i164-182o188-209i221-244o256-274i329- 355o367-386i406-425o431-455i475-493o499-521i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_60345A COG:P; EggNog:ENOG410PI23; InterPro:IPR006153,IPR038770; PFAM:PF00999; TransMembrane:12 (o30-47i59-77o89-110i122-147o159-184i196-220o226-246i267- 300o345-367i379-404o410-432i480-499o); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0015299 - solute:proton antiporter activity [Evidence IEA]; go_process: GO:0006812 - cation transport [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_60346S COG:Q; EggNog:ENOG410PG34; InterPro:IPR001128,IPR017972,IPR002401,IPR036396; PFAM:PF00067; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_60347A COG:G; EggNog:ENOG410PKN9; InterPro:IPR006045,IPR014710,IPR011051,IPR017774; PFAM:PF07883,PF00190; SECRETED:SignalP(1-24); go_process: GO:0033609 - oxalate metabolic process [Evidence IEA] AKAW2_60348A COG:I; EggNog:ENOG410PHWQ; InterPro:IPR006693,IPR029058; MEROPS:MER0208659; PFAM:PF04083; TransMembrane:3 (o125-151i432-451o457-476i); go_process: GO:0006629 - lipid metabolic process [Evidence IEA] AKAW2_60349A COG:A; EggNog:ENOG410PFSV; InterPro:IPR005829,IPR005828,IPR003663,IPR036259, IPR020846; PFAM:PF00083,PF07690; TransMembrane:10 (i12-34o73-93i100-119o125-146i158-178o190-211i342-366o372- 396i408-425o445-463i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_60350A COG:L; EggNog:ENOG410PIGX; InterPro:IPR033308,IPR004843; PFAM:PF00149; TransMembrane:3 (i63-85o511-531i632-652o); go_function: GO:0016787 - hydrolase activity [Evidence IEA]; go_process: GO:0006506 - GPI anchor biosynthetic process [Evidence IEA] AKAW2_60351A COG:P; EggNog:ENOG410PHDN; InterPro:IPR027469,IPR002524,IPR036837; PFAM:PF01545; TransMembrane:6 (i9-30o42-59i80-99o111-132i307-330o342-359i); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0008324 - cation transmembrane transporter activity [Evidence IEA]; go_process: GO:0006812 - cation transport [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_60352A COG:S; EggNog:ENOG410PXRU AKAW2_60353S COG:E; EggNog:ENOG410PV94; InterPro:IPR002293; PFAM:PF00324,PF13520; TransMembrane:6 (i30-51o85-109i130-151o163-180i192-221o233-255i); go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_60355S COG:S; EggNog:ENOG410PYVS; TransMembrane:3 (o262-281i374-392o398-416i) AKAW2_60356S CAZy:AA3; COG:E; EggNog:ENOG410PFN0; InterPro:IPR012132,IPR036188,IPR000172,IPR007867; PFAM:PF05199,PF00732; go_function: GO:0016614 - oxidoreductase activity, acting on CH-OH group of donors [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_60357S COG:S; EggNog:ENOG410PYT7; InterPro:IPR011057,IPR006913; PFAM:PF04828; go_function: GO:0016846 - carbon-sulfur lyase activity [Evidence IEA] AKAW2_60358A COG:S; EggNog:ENOG410Q1WN; InterPro:IPR001338; PFAM:PF01185; SECRETED:SignalP(1-18); go_component: GO:0009277 - fungal-type cell wall [Evidence IEA]; go_function: GO:0005199 - structural constituent of cell wall [Evidence IEA] AKAW2_60359S COG:J; EggNog:ENOG410PGSY; InterPro:IPR007783; PFAM:PF05091; go_component: GO:0005737 - cytoplasm [Evidence IEA]; go_component: GO:0005852 - eukaryotic translation initiation factor 3 complex [Evidence IEA]; go_function: GO:0003743 - translation initiation factor activity [Evidence IEA] AKAW2_60360A COG:S; EggNog:ENOG410PQYN; InterPro:IPR002925,IPR029058; PFAM:PF12697,PF02129,PF01738; SECRETED:SignalP(1-19); go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_60361S COG:Q; EggNog:ENOG410PUWG; InterPro:IPR036291 AKAW2_60362S COG:Q; EggNog:ENOG410Q8MJ; InterPro:IPR036291,IPR002347,IPR020904; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_60363S COG:O; EggNog:ENOG410Q2X2; InterPro:IPR001762,IPR024079,IPR001590,IPR036436; MEROPS:MER0182135; PFAM:PF01421,PF13688,PF13574,PF13582,PF13583; SECRETED:SignalP(1-22); TransMembrane:1 (n7-17c22/23o491-513i); go_function: GO:0004222 - metalloendopeptidase activity [Evidence IEA]; go_function: GO:0008237 - metallopeptidase activity [Evidence IEA]; go_process: GO:0006508 - proteolysis [Evidence IEA] AKAW2_60364S COG:S; EggNog:ENOG410PQBQ; InterPro:IPR021833; PFAM:PF11905 AKAW2_60365S COG:S; EggNog:ENOG410PVFN; InterPro:IPR036864,IPR001138; PFAM:PF00172; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_60366A COG:S; EggNog:ENOG410PJSX AKAW2_60367S COG:S; EggNog:ENOG410PSYC; TransMembrane:1 (o324-341i) AKAW2_60368A COG:S; EggNog:ENOG410QDBA; InterPro:IPR025239,IPR039249,IPR013087,IPR021933, IPR007042; PFAM:PF04959,PF12066,PF13821 AKAW2_60369A BUSCO:EOG09263KEE; COG:K; EggNog:ENOG410PQKV; InterPro:IPR001289; PFAM:PF02045; go_function: GO:0003700 - DNA-binding transcription factor activity [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_60370S COG:Z; EggNog:ENOG410PJZQ; InterPro:IPR027417,IPR019821,IPR036961,IPR022140, IPR001849,IPR011993,IPR027640,IPR008984,IPR032405, IPR001752,IPR000253,IPR022164; PFAM:PF16183,PF00169,PF16796,PF12473,PF12423, PF00225; go_function: GO:0003777 - microtubule motor activity [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0008017 - microtubule binding [Evidence IEA]; go_process: GO:0007018 - microtubule-based movement [Evidence IEA] AKAW2_60371A CAZy:GH43; COG:G; EggNog:ENOG410PN43; InterPro:IPR023296,IPR006710; PFAM:PF04616; SECRETED:SignalP(1-23); go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_60372A CAZy:GT90; COG:S; EggNog:ENOG410PMW2; InterPro:IPR006598; PFAM:PF05686; TransMembrane:1 (i12-34o) AKAW2_60373A COG:O; EggNog:ENOG410PHEM; InterPro:IPR014851,IPR003959,IPR003960,IPR027417, IPR003593; PFAM:PF08740,PF00004; TransMembrane:2 (o32-52i59-78o); go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA] AKAW2_60374A BUSCO:EOG09261G4Z; COG:S; EggNog:ENOG410PH98; InterPro:IPR017850,IPR002591; PFAM:PF01663; TransMembrane:1 (i163-182o); go_function: GO:0003824 - catalytic activity [Evidence IEA] AKAW2_60375S SECRETED:SignalP(1-20); TransMembrane:1 (n7-15c20/21o230-248i) AKAW2_60376A COG:K; EggNog:ENOG410PS7I; TransMembrane:1 (i895-917o) AKAW2_60377A COG:K; EggNog:ENOG410PS7I; InterPro:IPR011598,IPR036638,IPR037933; PFAM:PF00010; go_component: GO:0071339 - MLL1 complex [Evidence IEA]; go_component: GO:0090575 - RNA polymerase II transcription regulator complex [Evidence IEA]; go_function: GO:0046983 - protein dimerization activity [Evidence IEA] AKAW2_60378A BUSCO:EOG09260ZG2; COG:B; EggNog:ENOG410PGA6; InterPro:IPR005123,IPR043044,IPR006620,IPR039558, IPR019601; PFAM:PF10637,PF13640,PF13661; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0016706 - 2-oxoglutarate-dependent dioxygenase activity [Evidence IEA]; go_function: GO:0031418 - L-ascorbic acid binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_60379S COG:S; EggNog:ENOG410PS1J; InterPro:IPR037830 AKAW2_60381A COG:I; EggNog:ENOG410PHMG; InterPro:IPR001753,IPR029045; PFAM:PF00378; go_function: GO:0003824 - catalytic activity [Evidence IEA] AKAW2_60382S COG:S; EggNog:ENOG410Q1IQ AKAW2_60383A BUSCO:EOG09263U08; COG:K; EggNog:ENOG410PNAA; InterPro:IPR037817,IPR006751; PFAM:PF04658; go_component: GO:0005669 - transcription factor TFIID complex [Evidence IEA]; go_process: GO:0006367 - transcription initiation from RNA polymerase II promoter [Evidence IEA] AKAW2_60384S COG:S; EggNog:ENOG410PPW0; InterPro:IPR009072,IPR006565; PFAM:PF07524; go_function: GO:0046982 - protein heterodimerization activity [Evidence IEA] AKAW2_60385S COG:K; EggNog:ENOG410PIA6; InterPro:IPR038499,IPR004328,IPR037505; go_process: GO:0071467 - cellular response to pH [Evidence IEA] AKAW2_60386A COG:S; EggNog:ENOG410PPZ4; InterPro:IPR039993 AKAW2_60387A CAZy:GT34; COG:G; EggNog:ENOG410PHXF; InterPro:IPR008630; PFAM:PF05637; TransMembrane:1 (i129-148o); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0016757 - transferase activity, transferring glycosyl groups [Evidence IEA] AKAW2_60388A COG:S; EggNog:ENOG410Q2D3 AKAW2_60389A COG:T; EggNog:ENOG410PG0H; InterPro:IPR017441,IPR008271,IPR008984,IPR000253, IPR000719,IPR011009; PFAM:PF00498,PF07714,PF00069; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_60390A COG:E; EggNog:ENOG410PGQW; InterPro:IPR023603,IPR001597,IPR015424,IPR015421, IPR015422; PFAM:PF01212; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0016829 - lyase activity [Evidence IEA]; go_process: GO:0006520 - cellular amino acid metabolic process [Evidence IEA] AKAW2_60391S COG:S; EggNog:ENOG410Q2EE AKAW2_60392A COG:L; EggNog:ENOG410PGWF; InterPro:IPR012337,IPR036397,IPR013520,IPR034922; PFAM:PF00929; go_function: GO:0003676 - nucleic acid binding [Evidence IEA] AKAW2_60393S COG:O; EggNog:ENOG410PFJ2; InterPro:IPR002109,IPR036249,IPR004480,IPR033658, IPR013766; PFAM:PF00462,PF00085; go_function: GO:0015035 - protein disulfide oxidoreductase activity [Evidence IEA] AKAW2_60394A COG:I; EggNog:ENOG410PFA3; InterPro:IPR042098,IPR038492,IPR003819; PFAM:PF02668; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_60395S COG:C; EggNog:ENOG410PGGY; InterPro:IPR018108,IPR023395,IPR002067; PFAM:PF00153; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_60396A COG:Z; EggNog:ENOG410PJZJ; InterPro:IPR023123,IPR008280,IPR036525,IPR037103, IPR000217,IPR018316,IPR003008,IPR002452,IPR017975; PFAM:PF03953,PF00091; go_component: GO:0005874 - microtubule [Evidence IEA]; go_function: GO:0003924 - GTPase activity [Evidence IEA]; go_function: GO:0005200 - structural constituent of cytoskeleton [Evidence IEA]; go_function: GO:0005525 - GTP binding [Evidence IEA]; go_process: GO:0007017 - microtubule-based process [Evidence IEA] AKAW2_60398S COG:M; EggNog:ENOG410PF8H; InterPro:IPR010920,IPR011992,IPR016688,IPR006685, IPR002048,IPR018247; PFAM:PF00924; TransMembrane:6 (i163-185o191-211i244-262o282-299i505-528o534-557i); go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0005509 - calcium ion binding [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_60399A COG:T; EggNog:ENOG410QED5; InterPro:IPR000014,IPR008271,IPR001789,IPR000961, IPR011006,IPR000719,IPR011009; PFAM:PF00072,PF07714,PF00069; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0004674 - protein serine/threonine kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0000160 - phosphorelay signal transduction system [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_60400A CAZy:AA3; COG:E; EggNog:ENOG410PJ5E; InterPro:IPR012132,IPR036188,IPR000172,IPR007867; PFAM:PF05199,PF00732; SECRETED:SignalP(1-20); go_function: GO:0016614 - oxidoreductase activity, acting on CH-OH group of donors [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_60401A COG:G; EggNog:ENOG410PG64; InterPro:IPR036291,IPR002225; PFAM:PF04321,PF01073,PF16363,PF07993,PF01370; TransMembrane:1 (i7-27o); go_function: GO:0003854 - 3-beta-hydroxy-delta5-steroid dehydrogenase activity [Evidence IEA]; go_function: GO:0016616 - oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Evidence IEA]; go_process: GO:0006694 - steroid biosynthetic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_60402A COG:O; EggNog:ENOG410QE88; InterPro:IPR016135,IPR000608; PFAM:PF00179 AKAW2_60404S BUSCO:EOG09260CKC; COG:T; EggNog:ENOG410PFBF; InterPro:IPR001781,IPR000198,IPR008936; PFAM:PF00620,PF00412; go_process: GO:0007165 - signal transduction [Evidence IEA] AKAW2_60405A COG:S; EggNog:ENOG410PR02; InterPro:IPR018851; PFAM:PF10444 AKAW2_60406S COG:O; EggNog:ENOG410PFS5; InterPro:IPR002035,IPR027040,IPR036465,IPR003903; PFAM:PF13519; go_component: GO:0008540 - proteasome regulatory particle, base subcomplex [Evidence IEA]; go_process: GO:0006511 - ubiquitin-dependent protein catabolic process [Evidence IEA] AKAW2_60407A BUSCO:EOG09265822; COG:U; EggNog:ENOG410PRFI; InterPro:IPR007233,IPR011012; TransMembrane:1 (o12-31i); go_component: GO:0030008 - TRAPP complex [Evidence IEA]; go_process: GO:0016192 - vesicle-mediated transport [Evidence IEA] AKAW2_60408A COG:Q; EggNog:ENOG410Q1GX; InterPro:IPR002935,IPR029063; PFAM:PF13578,PF01596; go_function: GO:0008171 - O-methyltransferase activity [Evidence IEA] AKAW2_60409A COG:C; EggNog:ENOG410QDJM; InterPro:IPR039556,IPR015813,IPR040442; PFAM:PF13714; go_function: GO:0003824 - catalytic activity [Evidence IEA] AKAW2_60410A COG:S; EggNog:ENOG410PQTY; InterPro:IPR013087,IPR039970; go_function: GO:0003700 - DNA-binding transcription factor activity [Evidence IEA] AKAW2_60411A COG:Q; EggNog:ENOG410PFN7; InterPro:IPR034001,IPR043926,IPR027417,IPR003593, IPR010929,IPR017871,IPR029481,IPR003439,IPR013525, IPR034003; PFAM:PF01061,PF00005,PF06422,PF14510; TransMembrane:13 (o515-539i551-573o593-617i629-648o660-680i768-785o1153- 1171i1183-1205o1217-1239i1260-1286o1306-1328i1340- 1363o1456-1477i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA]; go_function: GO:0042626 - ATPase-coupled transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_60412S COG:T; EggNog:ENOG410Q10U; InterPro:IPR000219,IPR041675,IPR001180,IPR035899, IPR001849; PFAM:PF15405,PF00780,PF00621; go_function: GO:0005085 - guanyl-nucleotide exchange factor activity [Evidence IEA] AKAW2_60413A BUSCO:EOG09260K4B; COG:I; EggNog:ENOG410PIGF; InterPro:IPR011992,IPR035969,IPR000195; PFAM:PF00566 AKAW2_60414A COG:S; EggNog:ENOG410PPQG; SECRETED:SignalP(1-18); TransMembrane:1 (n6-14c18/19o308-337i) AKAW2_60415A TransMembrane:1 (o564-583i) AKAW2_60416A COG:Q; EggNog:ENOG410PF95; InterPro:IPR036291,IPR002347; PFAM:PF08659,PF00106,PF13561; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_60417S COG:S; EggNog:ENOG410PPXI; TransMembrane:3 (n10-20c28/29o57-75i84-103o163-181i) AKAW2_60418A COG:S; EggNog:ENOG410PNI3; TransMembrane:1 (i214-233o) AKAW2_60419A COG:E,I; EggNog:ENOG410PKRU; InterPro:IPR011763,IPR011762,IPR029045,IPR034733; PFAM:PF01039; go_function: GO:0016874 - ligase activity [Evidence IEA] AKAW2_60420S COG:C; EggNog:ENOG410PM09; InterPro:IPR000089,IPR011761,IPR016185,IPR011764, IPR005479,IPR005482,IPR005481,IPR011054,IPR011053; PFAM:PF02786,PF00364,PF02655,PF02785,PF07478, PF00289; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0046872 - metal ion binding [Evidence IEA] AKAW2_60421S COG:U; EggNog:ENOG410QDVJ; InterPro:IPR000300,IPR036691; TransMembrane:1 (i403-435o); go_process: GO:0046856 - phosphatidylinositol dephosphorylation [Evidence IEA] AKAW2_60422S COG:S; EggNog:ENOG410PTDG AKAW2_60423S COG:S; EggNog:ENOG410PQEI; InterPro:IPR000253; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_60424A COG:T; EggNog:ENOG410PH8C; InterPro:IPR004148,IPR027267,IPR036028,IPR001452; PFAM:PF03114,PF00018,PF14604,PF07653; go_component: GO:0005737 - cytoplasm [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_60425S COG:S; EggNog:ENOG410PRPS; InterPro:IPR018838; PFAM:PF10382 AKAW2_60426A COG:Z; EggNog:ENOG410PMDA; InterPro:IPR001849,IPR024774,IPR011993; PFAM:PF12814,PF00169; go_component: GO:0005938 - cell cortex [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_function: GO:0005543 - phospholipid binding [Evidence IEA]; go_process: GO:0032065 - maintenance of protein location in cell cortex [Evidence IEA] AKAW2_60427S COG:S; EggNog:ENOG410PV22; InterPro:IPR021838; PFAM:PF11913; SECRETED:SignalP(1-26) AKAW2_60428A BUSCO:EOG092617RY; COG:L; EggNog:ENOG410PFW8; InterPro:IPR006165,IPR006164,IPR003034,IPR016194, IPR036465,IPR027388,IPR005160,IPR005161,IPR036361; PFAM:PF03730,PF03731,PF02735,PF02037; go_component: GO:0005634 - nucleus [Evidence IEA]; go_component: GO:0043564 - Ku70:Ku80 complex [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0003678 - DNA helicase activity [Evidence IEA]; go_function: GO:0003684 - damaged DNA binding [Evidence IEA]; go_function: GO:0042162 - telomeric DNA binding [Evidence IEA]; go_process: GO:0000723 - telomere maintenance [Evidence IEA]; go_process: GO:0006303 - double-strand break repair via nonhomologous end joining [Evidence IEA] AKAW2_60429S BUSCO:EOG09262BHE; COG:H; EggNog:ENOG410PFNF; InterPro:IPR033659,IPR033644,IPR001015,IPR019772; PFAM:PF00762; go_function: GO:0004325 - ferrochelatase activity [Evidence IEA]; go_process: GO:0006783 - heme biosynthetic process [Evidence IEA] AKAW2_60430S COG:U; EggNog:ENOG410QE60; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i79-98o149-168i180-198o210-234i246-269o275-297i368- 393o405-429i449-467o473-491i512-531o537-559i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_60431S COG:S; EggNog:ENOG410PVNR AKAW2_60432S COG:S; EggNog:ENOG410Q2H7; InterPro:IPR011057,IPR006913; PFAM:PF04828; go_function: GO:0016846 - carbon-sulfur lyase activity [Evidence IEA] AKAW2_60433S COG:S; EggNog:ENOG410PH5P; InterPro:IPR036378,IPR000782; PFAM:PF02469 AKAW2_60434A COG:C; EggNog:ENOG410PNAU; InterPro:IPR011032,IPR020843,IPR036291; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA] AKAW2_60435S COG:S; EggNog:ENOG410PVNX; InterPro:IPR036864,IPR001138; PFAM:PF00172; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_60436S COG:S; EggNog:ENOG410PR3N AKAW2_60437S COG:E; EggNog:ENOG410PG4E; InterPro:IPR006222,IPR027266,IPR029043,IPR006076, IPR013977,IPR032503,IPR036188; PFAM:PF08669,PF01571,PF16350,PF01266; go_function: GO:0005515 - protein binding [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_60438A COG:S; EggNog:ENOG410PU0E AKAW2_60439S COG:S; EggNog:ENOG410PZAI AKAW2_60440S COG:S; EggNog:ENOG410PSYB; InterPro:IPR029063 AKAW2_60441S SECRETED:SignalP(1-17) AKAW2_60442S COG:S; EggNog:ENOG410PJ7E; InterPro:IPR029058; MEROPS:MER0209971 AKAW2_60443S COG:E; EggNog:ENOG410PHTX; InterPro:IPR019818,IPR024084; PFAM:PF00180; go_function: GO:0000287 - magnesium ion binding [Evidence IEA]; go_function: GO:0016616 - oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Evidence IEA]; go_function: GO:0051287 - NAD binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_60444S COG:S; EggNog:ENOG410PVYV AKAW2_60445A COG:E; EggNog:ENOG410PIX0; InterPro:IPR004839,IPR015424,IPR015421; PFAM:PF00155; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0030170 - pyridoxal phosphate binding [Evidence IEA]; go_process: GO:0009058 - biosynthetic process [Evidence IEA] AKAW2_60446S COG:S; EggNog:ENOG410PVE8; InterPro:IPR001138,IPR036864; TransMembrane:1 (o541-561i); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_60447S BUSCO:EOG09260OM6; COG:E,J; EggNog:ENOG410PFJH; InterPro:IPR017871,IPR027417,IPR003593,IPR003439, IPR032781; PFAM:PF12848,PF00005; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA] AKAW2_60448A COG:J; EggNog:ENOG410PGA5; InterPro:IPR001451,IPR029044; PFAM:PF00132 AKAW2_60449A COG:S; EggNog:ENOG410Q2AQ; InterPro:IPR036291,IPR008030; PFAM:PF13460,PF05368 AKAW2_60450S BUSCO:EOG09263S2P; COG:U; EggNog:ENOG410PIHA; InterPro:IPR006639,IPR007369; MEROPS:MER0027251; PFAM:PF04258; TransMembrane:9 (o28-47i84-102o114-130i226-246o252-268i275-295o338- 357i416-438o444-462i); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0004190 - aspartic-type endopeptidase activity [Evidence IEA] AKAW2_60451S COG:Q; EggNog:ENOG410PHZH; InterPro:IPR002347,IPR036291; PFAM:PF00106,PF13561,PF08659,PF01370; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_60452A COG:D; EggNog:ENOG410PHTF; InterPro:IPR003691; PFAM:PF02537; TransMembrane:7 (i67-87o93-116i159-187o207-235i256-275o287-308i392-416o); go_component: GO:0016021 - integral component of membrane [Evidence IEA] AKAW2_60453A COG:S; EggNog:ENOG410PFW1; InterPro:IPR013927; go_function: GO:0003714 - transcription corepressor activity [Evidence IEA] AKAW2_60454S BUSCO:EOG09262OX9; COG:E; EggNog:ENOG410PG5K; InterPro:IPR004636,IPR005814,IPR015424,IPR015421, IPR015422; PFAM:PF00202; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0008483 - transaminase activity [Evidence IEA]; go_function: GO:0030170 - pyridoxal phosphate binding [Evidence IEA]; go_process: GO:0006525 - arginine metabolic process [Evidence IEA] AKAW2_60455A CAZy:AA11; COG:S; EggNog:ENOG410QDDW; SECRETED:SignalP(1-17) AKAW2_60456A BUSCO:EOG09262A8G; COG:E; EggNog:ENOG410PJQI; InterPro:IPR001518,IPR023434,IPR024074,IPR018223, IPR014729; PFAM:PF00764; go_function: GO:0004055 - argininosuccinate synthase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006526 - arginine biosynthetic process [Evidence IEA] AKAW2_60457S BUSCO:EOG09264BIX; COG:O; EggNog:ENOG410PN42; InterPro:IPR010591; PFAM:PF06644; go_component: GO:0005739 - mitochondrion [Evidence IEA]; go_process: GO:0065003 - protein-containing complex assembly [Evidence IEA] AKAW2_60459A COG:C; EggNog:ENOG410PKDH; InterPro:IPR023210,IPR036812; PFAM:PF00248 AKAW2_60460A CAZy:CE10; COG:V; EggNog:ENOG410PVCQ; InterPro:IPR029058,IPR013094; MEROPS:MER0043146; PFAM:PF07859; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_60461A COG:C; EggNog:ENOG410PVRY; InterPro:IPR017938,IPR012675,IPR001041,IPR017927, IPR006058,IPR005302,IPR011037,IPR039261,IPR036010; PFAM:PF00111,PF03473; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0009055 - electron transfer activity [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0030151 - molybdenum ion binding [Evidence IEA]; go_function: GO:0030170 - pyridoxal phosphate binding [Evidence IEA]; go_function: GO:0051536 - iron-sulfur cluster binding [Evidence IEA]; go_function: GO:0051537 - 2 iron, 2 sulfur cluster binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_60462S COG:Q; EggNog:ENOG410PU7S; InterPro:IPR002925,IPR029058; PFAM:PF01738; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_60463A COG:I; EggNog:ENOG410PV30; InterPro:IPR006176,IPR006108,IPR036291,IPR008927, IPR013328; PFAM:PF02737,PF00725; TransMembrane:1 (i7-25o); go_function: GO:0003857 - 3-hydroxyacyl-CoA dehydrogenase activity [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0006631 - fatty acid metabolic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_60464S COG:I; EggNog:ENOG410PWA5; InterPro:IPR023606,IPR003673; PFAM:PF02515; go_function: GO:0008410 - CoA-transferase activity [Evidence IEA] AKAW2_60465A COG:C,H; EggNog:ENOG410PIWS; InterPro:IPR036188,IPR002938; PFAM:PF01494; go_function: GO:0071949 - FAD binding [Evidence IEA] AKAW2_60466S COG:I,J,T; EggNog:ENOG410PFMP; InterPro:IPR023631,IPR036928 AKAW2_60467S COG:I,J,T; EggNog:ENOG410PFMP; InterPro:IPR023631,IPR036928; PFAM:PF01425; SECRETED:SignalP(1-17) AKAW2_60468A COG:I; EggNog:ENOG410PKQX; InterPro:IPR042099,IPR000873,IPR025110; PFAM:PF00501,PF13193 AKAW2_60469S COG:I; EggNog:ENOG410PKEN; InterPro:IPR019826,IPR002018,IPR029058; MEROPS:MER0034664; PFAM:PF00135 AKAW2_60470A COG:S; EggNog:ENOG410PISV; InterPro:IPR001279,IPR036866 AKAW2_60471A COG:Q; EggNog:ENOG410PUZS; InterPro:IPR001447,IPR038765; PFAM:PF00797; go_function: GO:0016407 - acetyltransferase activity [Evidence IEA] AKAW2_60472A COG:Q; EggNog:ENOG410PUZS; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; TransMembrane:1 (o592-615i); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_60473A COG:G; EggNog:ENOG410Q07H; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690,PF00083; TransMembrane:12 (i107-127o147-166i178-198o204-226i238-260o266-287i344- 363o383-403i452-471o483-504i516-538o544-565i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_60474A COG:S; EggNog:ENOG410Q2FM AKAW2_60475S InterPro:IPR032675 AKAW2_60476A CAZy:CBM42; CAZy:GH54; COG:G; EggNog:ENOG410PKJG; InterPro:IPR038964,IPR013320,IPR036195,IPR007934, IPR015289; PFAM:PF09206,PF05270; SECRETED:SignalP(1-18); go_function: GO:0046556 - alpha-L-arabinofuranosidase activity [Evidence IEA]; go_process: GO:0019566 - arabinose metabolic process [Evidence IEA]; go_process: GO:0031221 - arabinan metabolic process [Evidence IEA]; go_process: GO:0046373 - L-arabinose metabolic process [Evidence IEA] AKAW2_60477A COG:O; EggNog:ENOG410PJPD; InterPro:IPR024079,IPR024077,IPR024080,IPR001567; MEROPS:MER0003110; PFAM:PF01432; TransMembrane:1 (o623-646i); go_function: GO:0004222 - metalloendopeptidase activity [Evidence IEA]; go_function: GO:0008237 - metallopeptidase activity [Evidence IEA]; go_process: GO:0006508 - proteolysis [Evidence IEA] AKAW2_60478S COG:S; EggNog:ENOG410PKSZ; InterPro:IPR036291,IPR002347; PFAM:PF00106; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_60480S SECRETED:SignalP(1-19) AKAW2_60481S COG:T; EggNog:ENOG410PII6; InterPro:IPR019819,IPR019826,IPR002018,IPR029058; MEROPS:MER0033188; PFAM:PF00135; SECRETED:SignalP(1-21) AKAW2_60482A CAZy:AA3; COG:E; EggNog:ENOG410PIZ6; InterPro:IPR012132,IPR036188,IPR000172,IPR007867; PFAM:PF05199,PF00732; go_function: GO:0016614 - oxidoreductase activity, acting on CH-OH group of donors [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_60483A COG:G; EggNog:ENOG410Q1W3; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:13 (o42-60i112-132o138-159i171-190o202-222i243-268o274- 290i311-337o349-370i379-397o409-428i440-464o517-535i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_60484A COG:S; EggNog:ENOG410PXVK; InterPro:IPR021054; PFAM:PF12296; SECRETED:SignalP(1-16) AKAW2_60485S COG:T; EggNog:ENOG410Q183; InterPro:IPR001610,IPR001789,IPR035965,IPR003594, IPR003661,IPR036890,IPR036097,IPR011006,IPR000700, IPR013767,IPR000014,IPR004358,IPR005467; PFAM:PF13426,PF00072,PF00512,PF00989,PF02518, PF08448; go_function: GO:0000155 - phosphorelay sensor kinase activity [Evidence IEA]; go_function: GO:0016772 - transferase activity, transferring phosphorus-containing groups [Evidence IEA]; go_process: GO:0000160 - phosphorelay signal transduction system [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA]; go_process: GO:0007165 - signal transduction [Evidence IEA]; go_process: GO:0016310 - phosphorylation [Evidence IEA] AKAW2_60486A COG:S; EggNog:ENOG410PIYI; InterPro:IPR011118,IPR029058; PFAM:PF07519 AKAW2_60487A SECRETED:SignalP(1-19) AKAW2_60488A COG:S; EggNog:ENOG410Q2R9; TransMembrane:6 (o67-87i136-154o166-184i205-225o254-278i336-356o) AKAW2_60489S COG:S; EggNog:ENOG410Q2QS; InterPro:IPR008979,IPR003305; PFAM:PF02018; go_function: GO:0016798 - hydrolase activity, acting on glycosyl bonds [Evidence IEA] AKAW2_60490S COG:S; EggNog:ENOG410PKGY; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_60491A COG:C,H; EggNog:ENOG410PM62; InterPro:IPR036188,IPR002938; PFAM:PF01494; TransMembrane:1 (n6-14c19/20o376-397i); go_function: GO:0071949 - FAD binding [Evidence IEA] AKAW2_60493A COG:S; EggNog:ENOG410Q28H; TransMembrane:1 (o29-47i) AKAW2_60495A COG:H; EggNog:ENOG410PGZC; InterPro:IPR006638,IPR002684,IPR007197,IPR013785, IPR010722,IPR024177; PFAM:PF06968,PF04055; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0004076 - biotin synthase activity [Evidence IEA]; go_function: GO:0051536 - iron-sulfur cluster binding [Evidence IEA]; go_process: GO:0009102 - biotin biosynthetic process [Evidence IEA] AKAW2_60496A COG:E; EggNog:ENOG410PG1W; InterPro:IPR005814,IPR027417,IPR015424,IPR004472, IPR015421; PFAM:PF13500,PF00202; go_function: GO:0000287 - magnesium ion binding [Evidence IEA]; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0004141 - dethiobiotin synthase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0008483 - transaminase activity [Evidence IEA]; go_function: GO:0030170 - pyridoxal phosphate binding [Evidence IEA]; go_process: GO:0009102 - biotin biosynthetic process [Evidence IEA] AKAW2_60497S COG:H; EggNog:ENOG410PI7U; InterPro:IPR004839,IPR015424,IPR015421,IPR015422; PFAM:PF00155; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0030170 - pyridoxal phosphate binding [Evidence IEA]; go_process: GO:0009058 - biosynthetic process [Evidence IEA] AKAW2_60498A COG:O; EggNog:ENOG410Q1B1; InterPro:IPR039903,IPR013083; go_function: GO:0061630 - ubiquitin protein ligase activity [Evidence IEA] AKAW2_60499S COG:E; EggNog:ENOG410PVW4; InterPro:IPR006076,IPR036188; PFAM:PF01266,PF13450; TransMembrane:2 (i7-30o78-95i); go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_60500S COG:I; EggNog:ENOG410PJMH; InterPro:IPR000873,IPR020845,IPR042099,IPR025110; PFAM:PF00501,PF13193 AKAW2_60501S COG:S; EggNog:ENOG410QEF8; InterPro:IPR006094,IPR036318,IPR016166,IPR012951; PFAM:PF08031,PF01565; SECRETED:SignalP(1-22); go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_function: GO:0071949 - FAD binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_60502S COG:S; EggNog:ENOG410PP1S; TransMembrane:6 (o19-40i52-75o95-115i127-153o173-197i209-230o) AKAW2_60503A COG:C; EggNog:ENOG410PFD1; InterPro:IPR019810,IPR002020,IPR036969,IPR016142, IPR016143; PFAM:PF00285; go_function: GO:0046912 - transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer [Evidence IEA] AKAW2_60504S COG:E,J; EggNog:ENOG410PG7H; InterPro:IPR016024,IPR011989,IPR000953,IPR017871, IPR003593,IPR016197,IPR027417,IPR023780,IPR003439; PFAM:PF00005,PF00385; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA] AKAW2_60505S COG:E; EggNog:ENOG410PG14; InterPro:IPR002293; PFAM:PF00324,PF13520; TransMembrane:10 (i41-60o80-101i122-146o166-185i197-215o274-296i379- 397o403-427i439-464o476-495i); go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_60506S CAZy:GH3; COG:G; EggNog:ENOG410PG84; InterPro:IPR017853,IPR036962,IPR002772,IPR036881, IPR026891,IPR013783,IPR001764; PFAM:PF14310,PF00933,PF01915; TransMembrane:1 (i146-170o); go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_60507S SECRETED:SignalP(1-26); TransMembrane:1 (n4-15c22/23o128-153i) AKAW2_60508S COG:S; EggNog:ENOG410PU4H AKAW2_60510S COG:S; EggNog:ENOG410PXGI AKAW2_60511A COG:C; EggNog:ENOG410PFY3; InterPro:IPR001465,IPR006252,IPR019830,IPR011076; PFAM:PF01274; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0004474 - malate synthase activity [Evidence IEA]; go_process: GO:0006097 - glyoxylate cycle [Evidence IEA] AKAW2_60512A COG:E; EggNog:ENOG410PFSC; InterPro:IPR014746,IPR036651,IPR008146; PFAM:PF00120; TransMembrane:1 (i46-63o); go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0004356 - glutamate-ammonia ligase activity [Evidence IEA]; go_process: GO:0006542 - glutamine biosynthetic process [Evidence IEA]; go_process: GO:0006807 - nitrogen compound metabolic process [Evidence IEA] AKAW2_60513S COG:Q; EggNog:ENOG410PHDQ; InterPro:IPR002347,IPR036291,IPR020904; PFAM:PF00106,PF13561,PF08659; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_60514A COG:P; EggNog:ENOG410PFD7; InterPro:IPR006068,IPR018303,IPR023298,IPR023299, IPR001757,IPR004014,IPR036412,IPR006414,IPR008250, IPR023214; PFAM:PF00689,PF13246,PF00122,PF00690,PF00702; TransMembrane:10 (i75-93o99-118i298-319o325-350i784-805o821-841i861- 888o908-927i969-990o1002-1021i); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0000166 - nucleotide binding [Evidence IEA]; go_function: GO:0019829 - ATPase-coupled cation transmembrane transporter activity [Evidence IEA]; go_process: GO:0006812 - cation transport [Evidence IEA] AKAW2_60516A COG:S; EggNog:ENOG410QECY; InterPro:IPR036864,IPR021858,IPR001138; PFAM:PF00172; TransMembrane:2 (i308-329o452-470i); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_60517S COG:E; EggNog:ENOG410PJ40; InterPro:IPR017144,IPR002933,IPR011650,IPR017439, IPR036264; MEROPS:MER0014418; PFAM:PF01546,PF07687; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_60518A COG:G; EggNog:ENOG410QDHP; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i52-75o95-112i119-137o143-168i180-202o208-229i280- 303o315-337i344-361o367-391i403-423o435-456i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_60519A COG:S; EggNog:ENOG410PIWY; InterPro:IPR036148,IPR012705,IPR042188,IPR005656, IPR042183; PFAM:PF03972; go_function: GO:0016829 - lyase activity [Evidence IEA]; go_function: GO:0047547 - 2-methylcitrate dehydratase activity [Evidence IEA]; go_function: GO:0051537 - 2 iron, 2 sulfur cluster binding [Evidence IEA]; go_process: GO:0019679 - propionate metabolic process, methylcitrate cycle [Evidence IEA] AKAW2_60521A COG:H; EggNog:ENOG410PJNQ; InterPro:IPR001525,IPR031303,IPR029063; go_function: GO:0008168 - methyltransferase activity [Evidence IEA] AKAW2_60522S BUSCO:EOG092621CP; COG:F; EggNog:ENOG410PGCV; InterPro:IPR029057,IPR029055,IPR017932,IPR035584, IPR000836,IPR005854; MEROPS:MER0004101; PFAM:PF13537,PF13522,PF00156; go_function: GO:0004044 - amidophosphoribosyltransferase activity [Evidence IEA]; go_process: GO:0009113 - purine nucleobase biosynthetic process [Evidence IEA]; go_process: GO:0009116 - nucleoside metabolic process [Evidence IEA] AKAW2_60523S COG:L; EggNog:ENOG410PK5N; InterPro:IPR011257,IPR003265,IPR023170; PFAM:PF00730; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_process: GO:0006281 - DNA repair [Evidence IEA]; go_process: GO:0006284 - base-excision repair [Evidence IEA] AKAW2_60524S COG:C; EggNog:ENOG410PFJC; InterPro:IPR015590,IPR029510,IPR016160,IPR016161, IPR016162,IPR016163; PFAM:PF00171; TransMembrane:1 (o25-44i); go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0016620 - oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_60525S COG:S; EggNog:ENOG410PTPY; TransMembrane:2 (i7-26o32-54i) AKAW2_60526A COG:S; EggNog:ENOG410PTC3 AKAW2_60527A COG:C; EggNog:ENOG410PN6K; InterPro:IPR036228,IPR008689; PFAM:PF05873; go_component: GO:0000276 - mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) [Evidence IEA]; go_function: GO:0015078 - proton transmembrane transporter activity [Evidence IEA]; go_process: GO:0015986 - ATP synthesis coupled proton transport [Evidence IEA] AKAW2_60528A COG:U; EggNog:ENOG410PN4Z; InterPro:IPR044034,IPR016641,IPR038187,IPR002715; PFAM:PF19026,PF01849; go_component: GO:0005854 - nascent polypeptide-associated complex [Evidence IEA] AKAW2_60529A BUSCO:EOG09265BWR; COG:J; EggNog:ENOG410PQ23; InterPro:IPR002784,IPR041985,IPR008991,IPR005824, IPR039660,IPR014722; PFAM:PF01929,PF00467; go_component: GO:0005840 - ribosome [Evidence IEA]; go_function: GO:0003723 - RNA binding [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_process: GO:0006412 - translation [Evidence IEA] AKAW2_60530A BUSCO:EOG09264P74; COG:S; EggNog:ENOG410PGDI; InterPro:IPR005578; PFAM:PF03878; TransMembrane:5 (i172-192o204-225i237-255o267-285i321-338o); go_component: GO:0005789 - endoplasmic reticulum membrane [Evidence IEA]; go_process: GO:0006888 - endoplasmic reticulum to Golgi vesicle-mediated transport [Evidence IEA] AKAW2_60531S COG:U; EggNog:ENOG410PFWV; InterPro:IPR036225,IPR013822,IPR027417,IPR003593, IPR000897,IPR042101,IPR011012,IPR007222; PFAM:PF02881,PF04086,PF00448; go_component: GO:0005785 - signal recognition particle receptor complex [Evidence IEA]; go_function: GO:0003924 - GTPase activity [Evidence IEA]; go_function: GO:0005047 - signal recognition particle binding [Evidence IEA]; go_function: GO:0005525 - GTP binding [Evidence IEA]; go_process: GO:0006614 - SRP-dependent cotranslational protein targeting to membrane [Evidence IEA]; go_process: GO:0006886 - intracellular protein transport [Evidence IEA] AKAW2_60532S COG:G; EggNog:ENOG410PHCQ; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:9 (i103-125o137-159i195-218o238-255i345-365o385-404i416- 435o447-476i524-544o); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_60533A COG:S; EggNog:ENOG410Q2PF; InterPro:IPR011990,IPR002893; PFAM:PF13374,PF13424; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_60535A COG:S; EggNog:ENOG410PT59; TransMembrane:1 (o776-797i) AKAW2_60536A COG:S; EggNog:ENOG410PSDD; InterPro:IPR007248; PFAM:PF04117; TransMembrane:4 (n9-16c24/25o40-61i97-118o138-159i166-184o); go_component: GO:0016021 - integral component of membrane [Evidence IEA] AKAW2_60537A COG:P; EggNog:ENOG410PNKF; InterPro:IPR036922,IPR017941,IPR001663; PFAM:PF00355; TransMembrane:2 (o12-30i290-308o); go_function: GO:0051537 - 2 iron, 2 sulfur cluster binding [Evidence IEA]; go_process: GO:0044237 - cellular metabolic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_60538A COG:S; EggNog:ENOG410PHZR; InterPro:IPR036922,IPR015879; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0051537 - 2 iron, 2 sulfur cluster binding [Evidence IEA]; go_process: GO:0044237 - cellular metabolic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_60539S BUSCO:EOG09260N53; COG:T; EggNog:ENOG410PFJW; InterPro:IPR035969,IPR000195; PFAM:PF00566 AKAW2_60540A COG:S; EggNog:ENOG410PQ3D; InterPro:IPR036534,IPR003108; go_function: GO:0008017 - microtubule binding [Evidence IEA] AKAW2_60541S COG:D,L; EggNog:ENOG410PG4K; InterPro:IPR016580,IPR007150; PFAM:PF04005; go_component: GO:0005730 - nucleolus [Evidence IEA]; go_component: GO:0030896 - checkpoint clamp complex [Evidence IEA]; go_process: GO:0000077 - DNA damage checkpoint [Evidence IEA] AKAW2_60542A COG:U; EggNog:ENOG410Q4KB; InterPro:IPR024880,IPR024340,IPR024468,IPR024298; PFAM:PF12932,PF12931,PF12935; go_process: GO:0006914 - autophagy [Evidence IEA]; go_process: GO:0048208 - COPII vesicle coating [Evidence IEA] AKAW2_60543S BUSCO:EOG09260AZM; COG:P; EggNog:ENOG410PG6X; InterPro:IPR018303,IPR023298,IPR023299,IPR001757, IPR023214,IPR006539,IPR036412,IPR008250,IPR032630, IPR032631; PFAM:PF13246,PF16209,PF00702,PF16212; TransMembrane:10 (i210-230o236-253i506-525o531-551i1057-1077o1083- 1105i1135-1153o1165-1184i1191-1212o1224-1246i); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0000166 - nucleotide binding [Evidence IEA]; go_function: GO:0000287 - magnesium ion binding [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0140326 - ATPase-coupled intramembrane lipid transporter activity [Evidence IEA]; go_process: GO:0015914 - phospholipid transport [Evidence IEA] AKAW2_60544A COG:G; EggNog:ENOG410PGQD; InterPro:IPR005829,IPR005828,IPR003663,IPR036259, IPR020846; PFAM:PF00083,PF07690; TransMembrane:11 (o67-85i137-157o163-185i197-219o225-246i317-338o353- 374i381-403o415-437i449-467o479-499i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_60545A COG:S; EggNog:ENOG410PR0P; InterPro:IPR028095; PFAM:PF14475 AKAW2_60546A BUSCO:EOG09264L3W; COG:A; EggNog:ENOG410PH0P; InterPro:IPR006958,IPR029004; PFAM:PF04874,PF01778 AKAW2_60547A BUSCO:EOG09260RVQ; COG:S; EggNog:ENOG410PG4S; InterPro:IPR040185,IPR012486,IPR021819; PFAM:PF07923,PF11882 AKAW2_60548A COG:I; EggNog:ENOG410PJMC; InterPro:IPR036938,IPR039667,IPR039666,IPR000326; PFAM:PF01569; TransMembrane:5 (o25-45i52-73o93-112i124-144o156-177i); go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_60549S COG:O; EggNog:ENOG410PM45; InterPro:IPR001841,IPR002867,IPR017907,IPR016135, IPR006575,IPR031127,IPR044066,IPR013083; PFAM:PF05773,PF01485; go_function: GO:0004842 - ubiquitin-protein transferase activity [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0016567 - protein ubiquitination [Evidence IEA] AKAW2_60550A COG:S; EggNog:ENOG410PQIJ; InterPro:IPR014839,IPR036322; TransMembrane:1 (i231-252o); go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_60551S COG:S; EggNog:ENOG410PRQJ; InterPro:IPR039207,IPR019315; PFAM:PF10159 AKAW2_60552A COG:G; EggNog:ENOG410PF8P; InterPro:IPR031631,IPR038518,IPR008928,IPR004888, IPR031335,IPR012341; PFAM:PF03200,PF16923; SECRETED:SignalP(1-16); go_function: GO:0004573 - mannosyl-oligosaccharide glucosidase activity [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA]; go_process: GO:0009311 - oligosaccharide metabolic process [Evidence IEA] AKAW2_60553A COG:E; EggNog:ENOG410PHSE; InterPro:IPR006076,IPR036188; PFAM:PF01266,PF13450; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_60554A COG:A; EggNog:ENOG410PRZW; InterPro:IPR018247,IPR013957; PFAM:PF08648; go_process: GO:0008380 - RNA splicing [Evidence IEA] AKAW2_60555S COG:S; EggNog:ENOG410PKXJ; InterPro:IPR019519; PFAM:PF10483; go_component: GO:0033588 - Elongator holoenzyme complex [Evidence IEA]; go_process: GO:0002098 - tRNA wobble uridine modification [Evidence IEA] AKAW2_60556A BUSCO:EOG09264IG5; COG:U; EggNog:ENOG410Q2U4; InterPro:IPR010908,IPR042855,IPR001388,IPR011012; PFAM:PF00957,PF13774; TransMembrane:1 (i196-214o); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_process: GO:0016192 - vesicle-mediated transport [Evidence IEA] AKAW2_60557S COG:S; EggNog:ENOG410PTFJ; InterPro:IPR028020; PFAM:PF13919 AKAW2_60558S COG:S; EggNog:ENOG410PIU3; InterPro:IPR030434,IPR008429; PFAM:PF05602; TransMembrane:6 (i20-39o342-363i375-399o405-422i473-492o498-524i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA] AKAW2_60559S COG:S; EggNog:ENOG410PI1T; InterPro:IPR012485; PFAM:PF07778; go_component: GO:0000776 - kinetochore [Evidence IEA]; go_process: GO:0034508 - centromere complex assembly [Evidence IEA] AKAW2_60560A COG:K; EggNog:ENOG410PIHS; InterPro:IPR017856,IPR029072,IPR002876,IPR026564; PFAM:PF01709 AKAW2_60561S BUSCO:EOG09260C5W; COG:S; EggNog:ENOG410PI9N; InterPro:IPR016024,IPR011989,IPR040108 AKAW2_60562A COG:S; EggNog:ENOG410PMGD; InterPro:IPR024461; PFAM:PF07798; TransMembrane:1 (o375-395i) AKAW2_60563A COG:S; EggNog:ENOG410PJ73; InterPro:IPR033370; PFAM:PF08700; go_component: GO:0017119 - Golgi transport complex [Evidence IEA]; go_process: GO:0006891 - intra-Golgi vesicle-mediated transport [Evidence IEA] AKAW2_60564S BUSCO:EOG09264WF4; COG:S; EggNog:ENOG410PJMN; InterPro:IPR009772; PFAM:PF07065 AKAW2_60565A COG:I; EggNog:ENOG410PJ85; InterPro:IPR001753,IPR029045; PFAM:PF16113,PF00378; go_function: GO:0003824 - catalytic activity [Evidence IEA] AKAW2_60566S COG:S; EggNog:ENOG410PSMJ; InterPro:IPR018625; PFAM:PF09803; TransMembrane:1 (i12-31o); go_component: GO:0005739 - mitochondrion [Evidence IEA]; go_process: GO:0033617 - mitochondrial cytochrome c oxidase assembly [Evidence IEA] AKAW2_60567A COG:S; EggNog:ENOG410PRW5; InterPro:IPR024512; PFAM:PF11779; TransMembrane:1 (o36-57i) AKAW2_60568S COG:J; EggNog:ENOG410QDMR; InterPro:IPR000352; PFAM:PF00472; go_function: GO:0003747 - translation release factor activity [Evidence IEA]; go_process: GO:0006415 - translational termination [Evidence IEA] AKAW2_60569A BUSCO:EOG09260OQ8; COG:U,Y; EggNog:ENOG410PFCM; InterPro:IPR016024,IPR011989,IPR001494,IPR005043, IPR013713; PFAM:PF03810,PF03378,PF08506; go_function: GO:0005515 - protein binding [Evidence IEA]; go_function: GO:0008536 - Ran GTPase binding [Evidence IEA]; go_process: GO:0006886 - intracellular protein transport [Evidence IEA] AKAW2_60570S COG:D,T; EggNog:ENOG410PJ9T; InterPro:IPR016024,IPR018515,IPR024584,IPR027107, IPR000331,IPR035974; PFAM:PF03542,PF11864,PF02145; TransMembrane:3 (o653-674i993-1011o1086-1104i); go_component: GO:0005634 - nucleus [Evidence IEA]; go_function: GO:0005096 - GTPase activator activity [Evidence IEA]; go_process: GO:0043547 - positive regulation of GTPase activity [Evidence IEA]; go_process: GO:0051056 - regulation of small GTPase mediated signal transduction [Evidence IEA] AKAW2_60572A COG:S; EggNog:ENOG410PSSX AKAW2_60573A COG:S; EggNog:ENOG410PRE4; TransMembrane:1 (o27-48i) AKAW2_60574S COG:J; EggNog:ENOG410PGRI; InterPro:IPR001313,IPR016024,IPR011989,IPR033712, IPR033133; PFAM:PF00806; go_function: GO:0003723 - RNA binding [Evidence IEA] AKAW2_60575S COG:A; EggNog:ENOG410PQ6J; InterPro:IPR013170; PFAM:PF08312 AKAW2_60576A BUSCO:EOG092610VI; COG:A; EggNog:ENOG410PFRV; InterPro:IPR011709,IPR027417,IPR001650,IPR014001, IPR007502,IPR011545,IPR002464; PFAM:PF04408,PF00270,PF07717,PF00271; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0004386 - helicase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA] AKAW2_60577S COG:S; EggNog:ENOG410PQQ7; InterPro:IPR018788; PFAM:PF10178 AKAW2_60578A COG:S; EggNog:ENOG410Q1VI AKAW2_60579S COG:S; EggNog:ENOG410PFY1; InterPro:IPR010347,IPR027415,IPR003903; PFAM:PF06087,PF02809; go_component: GO:0005634 - nucleus [Evidence IEA]; go_function: GO:0008081 - phosphoric diester hydrolase activity [Evidence IEA]; go_process: GO:0006281 - DNA repair [Evidence IEA] AKAW2_60580A COG:Q; EggNog:ENOG410QDR5; InterPro:IPR034001,IPR017871,IPR027417,IPR003593, IPR010929,IPR029481,IPR003439,IPR013525,IPR034003; PFAM:PF01061,PF00005,PF06422,PF14510; TransMembrane:14 (i548-568o580-602i623-646o658-677i689-708o800-833i1213- 1234o1246-1263i1283-1311o1323-1342i1354-1373o1385- 1405i1478-1498o1504-1523i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA]; go_function: GO:0042626 - ATPase-coupled transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_60581S COG:S; EggNog:ENOG410PV1H AKAW2_60582A COG:G,T; EggNog:ENOG410PPE9; InterPro:IPR018608; PFAM:PF09729 AKAW2_60584S COG:S; EggNog:ENOG410PZ49; SECRETED:SignalP(1-18); TransMembrane:1 (n4-15c23/24o222-246i) AKAW2_60585S COG:I; EggNog:ENOG410PHWV; InterPro:IPR000462,IPR043130; PFAM:PF01066; TransMembrane:4 (i113-135o141-160i181-205o284-302i); go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0016780 - phosphotransferase activity, for other substituted phosphate groups [Evidence IEA]; go_process: GO:0008654 - phospholipid biosynthetic process [Evidence IEA] AKAW2_60586A COG:J; EggNog:ENOG410PF8S; InterPro:IPR036188,IPR040131,IPR020595,IPR002218, IPR004416,IPR026904; PFAM:PF13932,PF01134; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_process: GO:0002098 - tRNA wobble uridine modification [Evidence IEA]; go_process: GO:0008033 - tRNA processing [Evidence IEA] AKAW2_60587A BUSCO:EOG09262X74; COG:U; EggNog:ENOG410PFB3; InterPro:IPR027537,IPR031468,IPR019411; PFAM:PF10296; TransMembrane:1 (o20-42i); go_component: GO:0032865 - ERMES complex [Evidence IEA]; go_function: GO:0008289 - lipid binding [Evidence IEA]; go_process: GO:0007005 - mitochondrion organization [Evidence IEA] AKAW2_60588S COG:C; EggNog:ENOG410PQ28; InterPro:IPR009567; PFAM:PF06682; SECRETED:SignalP(1-23); TransMembrane:1 (n4-15c23/24o165-187i); go_component: GO:0030176 - integral component of endoplasmic reticulum membrane [Evidence IEA]; go_process: GO:2001256 - regulation of store-operated calcium entry [Evidence IEA] AKAW2_60589A BUSCO:EOG09265C25; COG:K; EggNog:ENOG410PIBH; InterPro:IPR001005,IPR009057,IPR017174,IPR039467; PFAM:PF15963; go_component: GO:0000126 - transcription factor TFIIIB complex [Evidence IEA]; go_function: GO:0000995 - RNA polymerase III general transcription initiation factor activity [Evidence IEA]; go_process: GO:0006383 - transcription by RNA polymerase III [Evidence IEA] AKAW2_60590S COG:B; EggNog:ENOG410PJ71; InterPro:IPR001841,IPR017907,IPR013956,IPR013083; PFAM:PF13445,PF13923,PF13920,PF14447,PF00097, PF08647,PF13639; go_function: GO:0004842 - ubiquitin-protein transferase activity [Evidence IEA]; go_process: GO:0010390 - histone monoubiquitination [Evidence IEA] AKAW2_60591A COG:O; EggNog:ENOG410PM87; InterPro:IPR002639,IPR038277; PFAM:PF01730; go_function: GO:0016151 - nickel cation binding [Evidence IEA]; go_process: GO:0006807 - nitrogen compound metabolic process [Evidence IEA] AKAW2_60592S BUSCO:EOG09262Z14; COG:S; EggNog:ENOG410PG8X; InterPro:IPR011009,IPR034646,IPR004147; PFAM:PF03109 AKAW2_60593A CAZy:GT71; COG:G; EggNog:ENOG410PHW7; InterPro:IPR022751,IPR029044; PFAM:PF11051; go_function: GO:0016757 - transferase activity, transferring glycosyl groups [Evidence IEA]; go_process: GO:0006486 - protein glycosylation [Evidence IEA] AKAW2_60594A TransMembrane:2 (n4-15c19/20o29-48i60-81o) AKAW2_60595S COG:G; EggNog:ENOG410PIQS; InterPro:IPR037256,IPR014756,IPR030077,IPR013783, IPR032640,IPR006828; PFAM:PF16561,PF04739; go_component: GO:0031588 - nucleotide-activated protein kinase complex [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0007165 - signal transduction [Evidence IEA]; go_process: GO:0045859 - regulation of protein kinase activity [Evidence IEA] AKAW2_60596A BUSCO:EOG0926347W; COG:K; EggNog:ENOG410PG1E; InterPro:IPR034680,IPR017861,IPR000905,IPR043129; PFAM:PF00814; go_component: GO:0000408 - EKC/KEOPS complex [Evidence IEA]; go_process: GO:0002949 - tRNA threonylcarbamoyladenosine modification [Evidence IEA] AKAW2_60597S BUSCO:EOG09261WJ8; COG:S; EggNog:ENOG410PI4F; InterPro:IPR015353,IPR001214,IPR036464; PFAM:PF00856,PF09273; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_60598A BUSCO:EOG09263L7Y; COG:B; EggNog:ENOG410Q04X; InterPro:IPR024943,IPR019542; PFAM:PF10513; go_component: GO:0032777 - Piccolo NuA4 histone acetyltransferase complex [Evidence IEA]; go_component: GO:0035267 - NuA4 histone acetyltransferase complex [Evidence IEA]; go_process: GO:0006357 - regulation of transcription by RNA polymerase II [Evidence IEA] AKAW2_60599S COG:T; EggNog:ENOG410PG8E; InterPro:IPR011992,IPR002048,IPR018247,IPR015757; PFAM:PF00036,PF13499,PF13405,PF13202,PF13833; go_function: GO:0005509 - calcium ion binding [Evidence IEA]; go_function: GO:0008597 - calcium-dependent protein serine/threonine phosphatase regulator activity [Evidence IEA] AKAW2_60600A COG:T; EggNog:ENOG410PV41; InterPro:IPR000719,IPR011009,IPR008271,IPR017441; PFAM:PF00069; TransMembrane:2 (o20-43i222-241o); go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_60601A COG:S; EggNog:ENOG410PIMW; InterPro:IPR037460,IPR013830,IPR036514; PFAM:PF18647,PF13472; SECRETED:SignalP(1-14); go_function: GO:0016788 - hydrolase activity, acting on ester bonds [Evidence IEA] AKAW2_60602S CAZy:GH18; COG:G; EggNog:ENOG410PUJ4; InterPro:IPR036861,IPR011583,IPR029070,IPR001223, IPR017853,IPR001002,IPR001579,IPR018371; PFAM:PF00187,PF00704; SECRETED:SignalP(1-19); go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_function: GO:0008061 - chitin binding [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_60603S COG:S; EggNog:ENOG410PU2Y; InterPro:IPR024079; SECRETED:SignalP(1-21); go_function: GO:0008237 - metallopeptidase activity [Evidence IEA] AKAW2_60604S CAZy:CBM50; COG:S; EggNog:ENOG410PNG5; InterPro:IPR018392,IPR036779; PFAM:PF01476; SECRETED:SignalP(1-20) AKAW2_60605S COG:S; EggNog:ENOG410PNG5; InterPro:IPR018392,IPR036779; PFAM:PF01476 AKAW2_60606A COG:S; EggNog:ENOG410PTVY; InterPro:IPR036864,IPR021858,IPR001138; PFAM:PF00172; TransMembrane:1 (i206-226o); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_60607A COG:S; EggNog:ENOG410PQ5R AKAW2_60608A BUSCO:EOG09263K05; COG:J; EggNog:ENOG410PHT2; InterPro:IPR000754,IPR020568,IPR014721,IPR020574; PFAM:PF00380; go_component: GO:0005840 - ribosome [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_process: GO:0006412 - translation [Evidence IEA] AKAW2_60609S COG:J; EggNog:ENOG410PH8Q; InterPro:IPR036282,IPR036249,IPR040079,IPR001662, IPR010987,IPR004045,IPR004046,IPR036433; PFAM:PF00043,PF00647,PF02798; go_function: GO:0003746 - translation elongation factor activity [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0006414 - translational elongation [Evidence IEA]; go_process: GO:0006749 - glutathione metabolic process [Evidence IEA] AKAW2_60610A COG:K; EggNog:ENOG410PPV1; InterPro:IPR036412,IPR023214,IPR004274; PFAM:PF03031 AKAW2_60611S BUSCO:EOG09265M98; COG:J; EggNog:ENOG410PHSW; InterPro:IPR009292; PFAM:PF06102; go_process: GO:0000469 - cleavage involved in rRNA processing [Evidence IEA] AKAW2_60612A COG:S; EggNog:ENOG410PM4C AKAW2_60613A TransMembrane:2 (i29-50o56-82i) AKAW2_60614S COG:K; EggNog:ENOG410PQX3; InterPro:IPR033898,IPR036603,IPR009025,IPR008193; PFAM:PF01193,PF13656; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0003899 - DNA-directed 5'-3' RNA polymerase activity [Evidence IEA]; go_function: GO:0046983 - protein dimerization activity [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA] AKAW2_60615A COG:C; EggNog:ENOG410PPIW; InterPro:IPR016488; PFAM:PF05347,PF13233 AKAW2_60616S COG:Z; EggNog:ENOG410PPYM; InterPro:IPR037650; go_function: GO:0003729 - mRNA binding [Evidence IEA]; go_process: GO:0042273 - ribosomal large subunit biogenesis [Evidence IEA] AKAW2_60617A COG:S; EggNog:ENOG410PH5Z; InterPro:IPR000073,IPR029058; MEROPS:MER0059846; PFAM:PF12146; TransMembrane:1 (o12-32i) AKAW2_60618S COG:S; EggNog:ENOG410PIB2; InterPro:IPR001810,IPR036047; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_60619S COG:S; EggNog:ENOG410PIB2; InterPro:IPR019440; PFAM:PF10345; go_process: GO:0007064 - mitotic sister chromatid cohesion [Evidence IEA] AKAW2_60620A COG:B; EggNog:ENOG410PPUP; InterPro:IPR009072,IPR000164,IPR007125; PFAM:PF00125; go_component: GO:0000786 - nucleosome [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0046982 - protein heterodimerization activity [Evidence IEA] AKAW2_60621S COG:S; EggNog:ENOG410PIMP; InterPro:IPR007599; PFAM:PF04511; TransMembrane:4 (o29-53i65-88o108-141i153-178o) AKAW2_60622S CAZy:GT32; COG:M; EggNog:ENOG410PH27; InterPro:IPR029044,IPR007577; PFAM:PF04488; TransMembrane:3 (o6-31i198-217o270-293i) AKAW2_60623S COG:S; EggNog:ENOG410PQ6D; SECRETED:SignalP(1-19) AKAW2_60624A COG:E; EggNog:ENOG410PG7P; InterPro:IPR020565,IPR038494,IPR020568,IPR000807; PFAM:PF00475; go_function: GO:0004424 - imidazoleglycerol-phosphate dehydratase activity [Evidence IEA]; go_process: GO:0000105 - histidine biosynthetic process [Evidence IEA] AKAW2_60625S COG:S; EggNog:ENOG410PXS5; InterPro:IPR038882 AKAW2_60626S COG:S; EggNog:ENOG410PJT0; InterPro:IPR001849,IPR032675 AKAW2_60627A BUSCO:EOG09260JDM; COG:S; EggNog:ENOG410PIII; InterPro:IPR013943; PFAM:PF08634; go_component: GO:0005739 - mitochondrion [Evidence IEA]; go_process: GO:0000959 - mitochondrial RNA metabolic process [Evidence IEA] AKAW2_60628S COG:F; EggNog:ENOG410PFAD; InterPro:IPR016185,IPR037123,IPR016188,IPR010918, IPR036676,IPR011761,IPR000115,IPR020561,IPR020560, IPR020562,IPR013815,IPR011054,IPR004733,IPR036921; PFAM:PF02843,PF02844,PF01071,PF02769,PF00586; go_function: GO:0004637 - phosphoribosylamine-glycine ligase activity [Evidence IEA]; go_function: GO:0004641 - phosphoribosylformylglycinamidine cyclo-ligase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0046872 - metal ion binding [Evidence IEA]; go_process: GO:0006189 - 'de novo' IMP biosynthetic process [Evidence IEA]; go_process: GO:0009113 - purine nucleobase biosynthetic process [Evidence IEA] AKAW2_60629A COG:Z; EggNog:ENOG410Q83N; InterPro:IPR020902,IPR004000,IPR004001,IPR043129; PFAM:PF00022 AKAW2_60630S BUSCO:EOG0926448Q; COG:O; EggNog:ENOG410QD6U; InterPro:IPR016024,IPR011989,IPR013918; PFAM:PF08609,PF13513 AKAW2_60631A BUSCO:EOG092654VM; COG:S; EggNog:ENOG410PNEZ; InterPro:IPR007919; PFAM:PF05255; TransMembrane:4 (i21-41o61-80i101-125o137-159i) AKAW2_60632A COG:S; EggNog:ENOG410PVGB; InterPro:IPR041260; PFAM:PF18596 AKAW2_60633A COG:U; EggNog:ENOG410PQQA; InterPro:IPR007262; PFAM:PF04133; TransMembrane:4 (i7-26o32-50i71-92o98-122i) AKAW2_60634S BUSCO:EOG09264441; COG:O; EggNog:ENOG410PHF0; InterPro:IPR029055,IPR035144,IPR001353,IPR023332, IPR000426; MEROPS:MER0000549; PFAM:PF00227,PF10584; go_component: GO:0005839 - proteasome core complex [Evidence IEA]; go_component: GO:0019773 - proteasome core complex, alpha-subunit complex [Evidence IEA]; go_process: GO:0006511 - ubiquitin-dependent protein catabolic process [Evidence IEA]; go_process: GO:0051603 - proteolysis involved in cellular protein catabolic process [Evidence IEA] AKAW2_60635A COG:S; EggNog:ENOG410PHUH; InterPro:IPR031100,IPR005269; PFAM:PF03641 AKAW2_60636A BUSCO:EOG09264S40; COG:K; EggNog:ENOG410PPD9; InterPro:IPR016612,IPR038566,IPR007018; PFAM:PF04934; go_component: GO:0016592 - mediator complex [Evidence IEA]; go_function: GO:0003712 - transcription coregulator activity [Evidence IEA]; go_process: GO:0006357 - regulation of transcription by RNA polymerase II [Evidence IEA] AKAW2_60637A COG:S; EggNog:ENOG410PM3J; InterPro:IPR036890,IPR022155; PFAM:PF12449 AKAW2_60638S BUSCO:EOG0926077L; COG:U; EggNog:ENOG410QDBC; InterPro:IPR013935; PFAM:PF08626 AKAW2_60639A COG:J,U; EggNog:ENOG410Q8NB; InterPro:IPR001619,IPR043127,IPR036045,IPR043154, IPR027482; PFAM:PF00995; go_process: GO:0006904 - vesicle docking involved in exocytosis [Evidence IEA]; go_process: GO:0016192 - vesicle-mediated transport [Evidence IEA] AKAW2_60640S COG:I; EggNog:ENOG410PHXS; InterPro:IPR004299; PFAM:PF03062; TransMembrane:7 (o23-39i51-69o75-103i231-248o371-390i422-448o454-477i) AKAW2_60641A COG:S; EggNog:ENOG410PKY4; TransMembrane:2 (o611-632i676-698o) AKAW2_60642S COG:J; EggNog:ENOG410PHW1; InterPro:IPR013155,IPR009080,IPR025709,IPR001412, IPR014729,IPR009008,IPR015413,IPR002300,IPR002302; PFAM:PF00133,PF08264,PF13603; go_function: GO:0000166 - nucleotide binding [Evidence IEA]; go_function: GO:0002161 - aminoacyl-tRNA editing activity [Evidence IEA]; go_function: GO:0004812 - aminoacyl-tRNA ligase activity [Evidence IEA]; go_function: GO:0004823 - leucine-tRNA ligase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006418 - tRNA aminoacylation for protein translation [Evidence IEA]; go_process: GO:0006429 - leucyl-tRNA aminoacylation [Evidence IEA] AKAW2_60643S COG:C; EggNog:ENOG410PFPK; InterPro:IPR006140,IPR036291,IPR006139,IPR029753, IPR029752,IPR033689; PFAM:PF00389,PF02826; go_function: GO:0008863 - formate dehydrogenase (NAD+) activity [Evidence IEA]; go_function: GO:0016616 - oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Evidence IEA]; go_function: GO:0051287 - NAD binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_60644A COG:S; EggNog:ENOG410PT2G; TransMembrane:1 (o12-33i) AKAW2_60645S COG:T,Z; EggNog:ENOG410QDSA; InterPro:IPR014768,IPR016024,IPR011989,IPR010472, IPR010473,IPR014767,IPR042201,IPR015425; PFAM:PF06371,PF06367,PF02181; go_function: GO:0003779 - actin binding [Evidence IEA]; go_function: GO:0017048 - Rho GTPase binding [Evidence IEA]; go_process: GO:0016043 - cellular component organization [Evidence IEA]; go_process: GO:0030036 - actin cytoskeleton organization [Evidence IEA] AKAW2_60646S COG:J; EggNog:ENOG410PFQT; InterPro:IPR031168,IPR025867,IPR027266,IPR005225, IPR006073,IPR027417,IPR018948,IPR004520; PFAM:PF12631,PF01926; go_function: GO:0003924 - GTPase activity [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_function: GO:0005525 - GTP binding [Evidence IEA]; go_process: GO:0006400 - tRNA modification [Evidence IEA] AKAW2_60648A COG:M; EggNog:ENOG410PHPY; InterPro:IPR002110,IPR036770,IPR020683; PFAM:PF13857,PF12796,PF00023,PF13637,PF13606; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_60650A COG:E; EggNog:ENOG410PH1K; InterPro:IPR004418,IPR001030,IPR039386,IPR018136, IPR036008,IPR015931,IPR015928,IPR000573; PFAM:PF00330,PF00694; go_function: GO:0004409 - homoaconitate hydratase activity [Evidence IEA]; go_function: GO:0051539 - 4 iron, 4 sulfur cluster binding [Evidence IEA]; go_process: GO:0009085 - lysine biosynthetic process [Evidence IEA] AKAW2_60651A COG:C,H; EggNog:ENOG410PFUM; InterPro:IPR001834,IPR017938,IPR017927,IPR008333, IPR039261; PFAM:PF00970; TransMembrane:1 (i54-71o); go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_60652S COG:E; EggNog:ENOG410PI2A; InterPro:IPR002293; PFAM:PF00324,PF13520; TransMembrane:12 (i130-149o161-184i205-229o249-268i280-305o325-342i362- 384o404-425i482-503o509-533i545-565o571-587i); go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_60653A CAZy:GH32; COG:G; EggNog:ENOG410PKKH; InterPro:IPR001362,IPR013148,IPR013189,IPR013320, IPR023296; PFAM:PF00251,PF08244; go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_60654S COG:G; EggNog:ENOG410PKGK; InterPro:IPR005829,IPR005828,IPR003663,IPR036259, IPR020846; PFAM:PF00083,PF07690; TransMembrane:10 (i44-62o99-116i128-145o186-206i218-236o336-357i364- 385o391-411i432-454o466-485i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_60655A COG:K; EggNog:ENOG410PPI1; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_60656S COG:I,J,T; EggNog:ENOG410PFMP; InterPro:IPR023631,IPR036928; PFAM:PF01425 AKAW2_60657S CAZy:CE4; COG:G; EggNog:ENOG410PKEH; InterPro:IPR011330,IPR002509,IPR037950; PFAM:PF01522; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0016810 - hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_60658A COG:L; EggNog:ENOG410PFZH; InterPro:IPR003959,IPR027417,IPR003593,IPR013748, IPR008921; PFAM:PF13173,PF00004,PF08542; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA]; go_process: GO:0006260 - DNA replication [Evidence IEA] AKAW2_60659S COG:S; EggNog:ENOG410PTB4 AKAW2_60660A COG:U; EggNog:ENOG410PJSH; InterPro:IPR011990,IPR007317; PFAM:PF04190; TransMembrane:1 (o187-204i); go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0045048 - protein insertion into ER membrane [Evidence IEA] AKAW2_60661S COG:K; EggNog:ENOG410PIR0; InterPro:IPR039039,IPR013961; PFAM:PF08652 AKAW2_60662A BUSCO:EOG09262C5Z; COG:H; EggNog:ENOG410PGF7; InterPro:IPR036236,IPR018022,IPR039657,IPR027417, IPR030666; PFAM:PF01715,PF12874; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0052381 - tRNA dimethylallyltransferase activity [Evidence IEA]; go_process: GO:0008033 - tRNA processing [Evidence IEA] AKAW2_60663S BUSCO:EOG09263X4B; COG:K; EggNog:ENOG410PINB; InterPro:IPR027417,IPR003593,IPR003439; PFAM:PF00005; go_function: GO:0005524 - ATP binding [Evidence IEA] AKAW2_60664A COG:B,K; EggNog:ENOG410PGG4; InterPro:IPR037289,IPR011047,IPR036322,IPR015943, IPR001680,IPR020472,IPR017986; PFAM:PF00400; go_component: GO:0033588 - Elongator holoenzyme complex [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0002098 - tRNA wobble uridine modification [Evidence IEA] AKAW2_60665S BUSCO:EOG09265K1R; COG:O; EggNog:ENOG410PR1E; InterPro:IPR012675,IPR015221,IPR016155; PFAM:PF02597,PF09138; go_component: GO:0005737 - cytoplasm [Evidence IEA]; go_process: GO:0034227 - tRNA thio-modification [Evidence IEA] AKAW2_60666A COG:G; EggNog:ENOG410PG06; InterPro:IPR013079,IPR013078,IPR027417,IPR003094, IPR029033; PFAM:PF00300,PF01591; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0003873 - 6-phosphofructo-2-kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006000 - fructose metabolic process [Evidence IEA]; go_process: GO:0006003 - fructose 2,6-bisphosphate metabolic process [Evidence IEA] AKAW2_60667S BUSCO:EOG09262M2J; COG:U; EggNog:ENOG410PFY2; InterPro:IPR023614,IPR037930,IPR027246; PFAM:PF01459; go_component: GO:0005741 - mitochondrial outer membrane [Evidence IEA]; go_function: GO:0008320 - protein transmembrane transporter activity [Evidence IEA]; go_process: GO:0030150 - protein import into mitochondrial matrix [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_60668S BUSCO:EOG09262KXK; COG:T; EggNog:ENOG410PGBM; InterPro:IPR017441,IPR008271,IPR039192,IPR000719, IPR011009; PFAM:PF07714,PF00069; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_60669S BUSCO:EOG09260PI1; COG:A; EggNog:ENOG410PGW2; InterPro:IPR016024,IPR016021,IPR027159,IPR015172, IPR015174; PFAM:PF09088,PF09090; go_component: GO:0005846 - nuclear cap binding complex [Evidence IEA]; go_function: GO:0000339 - RNA cap binding [Evidence IEA]; go_process: GO:0016070 - RNA metabolic process [Evidence IEA]; go_process: GO:0045292 - mRNA cis splicing, via spliceosome [Evidence IEA]; go_process: GO:0051028 - mRNA transport [Evidence IEA] AKAW2_60670A COG:I; EggNog:ENOG410PG6G; InterPro:IPR006694; PFAM:PF04116; TransMembrane:3 (o82-108i128-147o167-187i); go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0008610 - lipid biosynthetic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_60671S COG:S; EggNog:ENOG410PFUA; InterPro:IPR036322,IPR015943,IPR001680,IPR019775, IPR020472,IPR013890,IPR017986; PFAM:PF08581,PF00400; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_60673S COG:K; EggNog:ENOG410PHIE; InterPro:IPR036236,IPR013087; PFAM:PF00096 AKAW2_60674A COG:C; EggNog:ENOG410PHZI; InterPro:IPR018108,IPR023395,IPR002067; PFAM:PF00153; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_60675A COG:S; EggNog:ENOG410PSNU; InterPro:IPR012621; PFAM:PF08038; TransMembrane:1 (i21-39o); go_component: GO:0005742 - mitochondrial outer membrane translocase complex [Evidence IEA]; go_process: GO:0030150 - protein import into mitochondrial matrix [Evidence IEA] AKAW2_60676S COG:A; EggNog:ENOG410PHEN; InterPro:IPR000504,IPR035979,IPR034159,IPR034158, IPR012677; PFAM:PF13893,PF00076; go_function: GO:0003676 - nucleic acid binding [Evidence IEA] AKAW2_60677A BUSCO:EOG09265I7S; COG:S; EggNog:ENOG410PR51; InterPro:IPR018559; PFAM:PF09435; TransMembrane:1 (o6-23i) AKAW2_60678S COG:J; EggNog:ENOG410PR32; InterPro:IPR002672,IPR029004; PFAM:PF01778; go_component: GO:0005840 - ribosome [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_process: GO:0006412 - translation [Evidence IEA] AKAW2_60679S COG:C; EggNog:ENOG410PGH8; InterPro:IPR015955,IPR001236,IPR036291,IPR001557, IPR010097,IPR001252,IPR022383; PFAM:PF00056,PF02866; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0016615 - malate dehydrogenase activity [Evidence IEA]; go_function: GO:0016616 - oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Evidence IEA]; go_function: GO:0030060 - L-malate dehydrogenase activity [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA]; go_process: GO:0006099 - tricarboxylic acid cycle [Evidence IEA]; go_process: GO:0006108 - malate metabolic process [Evidence IEA]; go_process: GO:0019752 - carboxylic acid metabolic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_60680A BUSCO:EOG09263RY2; COG:U; EggNog:ENOG410PKMP; InterPro:IPR024096,IPR037992,IPR007194; PFAM:PF04051; go_process: GO:0043087 - regulation of GTPase activity [Evidence IEA]; go_process: GO:0048193 - Golgi vesicle transport [Evidence IEA] AKAW2_60681A COG:K; EggNog:ENOG410PJSJ; InterPro:IPR003034,IPR023321,IPR004181,IPR036361, IPR038654,IPR013083; PFAM:PF14324,PF11789,PF02037,PF02891; go_function: GO:0008270 - zinc ion binding [Evidence IEA] AKAW2_60682S COG:S; EggNog:ENOG410PZQC; InterPro:IPR019434; PFAM:PF10338 AKAW2_60683S COG:T; EggNog:ENOG410PHUD; InterPro:IPR017850,IPR039527,IPR002591,IPR037674; TransMembrane:12 (i7-31o445-467i474-494o500-518i539-556o576-595i607- 629o649-673i727-746o766-787i808-829o841-859i); go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0051377 - mannose-ethanolamine phosphotransferase activity [Evidence IEA]; go_process: GO:0006506 - GPI anchor biosynthetic process [Evidence IEA] AKAW2_60684A COG:S; EggNog:ENOG410PRC6 AKAW2_60685A COG:D; EggNog:ENOG410PPWC AKAW2_60686A COG:D; EggNog:ENOG410PPWC; InterPro:IPR035979,IPR007201,IPR012677; PFAM:PF04059; go_function: GO:0003676 - nucleic acid binding [Evidence IEA] AKAW2_60687S BUSCO:EOG09260NY2; COG:U; EggNog:ENOG410PKAQ; InterPro:IPR042044,IPR042045,IPR007225; PFAM:PF04091; go_component: GO:0000145 - exocyst [Evidence IEA]; go_process: GO:0006904 - vesicle docking involved in exocytosis [Evidence IEA] AKAW2_60688A COG:K; EggNog:ENOG410PK7Z; InterPro:IPR009072,IPR007125,IPR027170; PFAM:PF00808; go_component: GO:0016602 - CCAAT-binding factor complex [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0003700 - DNA-binding transcription factor activity [Evidence IEA]; go_function: GO:0046982 - protein heterodimerization activity [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_60690S BUSCO:EOG092643NE; COG:S; EggNog:ENOG410PQHE; InterPro:IPR014810,IPR039883; PFAM:PF08698 AKAW2_60691A COG:F; EggNog:ENOG410PFFJ; InterPro:IPR000845,IPR035994,IPR011270,IPR018099, IPR011268; PFAM:PF01048; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0004731 - purine-nucleoside phosphorylase activity [Evidence IEA]; go_function: GO:0016763 - transferase activity, transferring pentosyl groups [Evidence IEA]; go_process: GO:0006139 - nucleobase-containing compound metabolic process [Evidence IEA]; go_process: GO:0009116 - nucleoside metabolic process [Evidence IEA] AKAW2_60692S COG:J; EggNog:ENOG410PMUZ; InterPro:IPR036838,IPR001848,IPR027486; PFAM:PF00338; go_component: GO:0005840 - ribosome [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_process: GO:0006412 - translation [Evidence IEA] AKAW2_60693S COG:J; EggNog:ENOG410PGYS; InterPro:IPR024109,IPR001412,IPR014729,IPR002305, IPR002306; PFAM:PF00579; TransMembrane:1 (o143-162i); go_function: GO:0000166 - nucleotide binding [Evidence IEA]; go_function: GO:0004812 - aminoacyl-tRNA ligase activity [Evidence IEA]; go_function: GO:0004830 - tryptophan-tRNA ligase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006418 - tRNA aminoacylation for protein translation [Evidence IEA]; go_process: GO:0006436 - tryptophanyl-tRNA aminoacylation [Evidence IEA] AKAW2_60694S COG:O; EggNog:ENOG410PIXI; InterPro:IPR021109,IPR033876,IPR001461,IPR001969, IPR033121; MEROPS:MER0003669; PFAM:PF00026,PF14543; SECRETED:SignalP(1-21); TransMembrane:1 (n4-16c21/22o464-484i); go_function: GO:0004190 - aspartic-type endopeptidase activity [Evidence IEA]; go_process: GO:0006508 - proteolysis [Evidence IEA] AKAW2_60695A COG:J; EggNog:ENOG410PPH2; InterPro:IPR002052,IPR029063,IPR025714; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0008168 - methyltransferase activity [Evidence IEA]; go_process: GO:0032259 - methylation [Evidence IEA] AKAW2_60696S COG:C; EggNog:ENOG410PFMQ; InterPro:IPR018108,IPR023395,IPR002067; PFAM:PF00153; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_60697S COG:J; EggNog:ENOG410PMXF; InterPro:IPR000039,IPR036227,IPR021131,IPR021132; PFAM:PF17135; go_component: GO:0005840 - ribosome [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_process: GO:0006412 - translation [Evidence IEA] AKAW2_60698A BUSCO:EOG0926388H; COG:E; EggNog:ENOG410PG7C; InterPro:IPR015590,IPR012134,IPR000965,IPR016161, IPR016162,IPR016163; PFAM:PF00171; go_function: GO:0004350 - glutamate-5-semialdehyde dehydrogenase activity [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0016620 - oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Evidence IEA]; go_function: GO:0050661 - NADP binding [Evidence IEA]; go_process: GO:0006561 - proline biosynthetic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_60699S COG:O,T; EggNog:ENOG410PP3T; InterPro:IPR037753; go_component: GO:0008180 - COP9 signalosome [Evidence IEA] AKAW2_60700A COG:I,U; EggNog:ENOG410PFD2; InterPro:IPR004177; PFAM:PF02862; go_function: GO:0046872 - metal ion binding [Evidence IEA] AKAW2_60701S BUSCO:EOG0926140Q; COG:Z; EggNog:ENOG410PGNK; InterPro:IPR011992,IPR039959,IPR001715,IPR001589, IPR036872; PFAM:PF00307; go_function: GO:0005515 - protein binding [Evidence IEA]; go_function: GO:0051015 - actin filament binding [Evidence IEA]; go_process: GO:0051017 - actin filament bundle assembly [Evidence IEA] AKAW2_60702A COG:A; EggNog:ENOG410PXS7; InterPro:IPR034403,IPR000504,IPR012677,IPR035979; PFAM:PF00076; go_function: GO:0003676 - nucleic acid binding [Evidence IEA] AKAW2_60703S COG:Q; EggNog:ENOG410PQHA; InterPro:IPR039298,IPR029069,IPR006683; PFAM:PF03061; go_function: GO:0047617 - acyl-CoA hydrolase activity [Evidence IEA] AKAW2_60704S COG:S; EggNog:ENOG410PJVD; InterPro:IPR039298,IPR001683,IPR003114,IPR036871, IPR013937; PFAM:PF02194,PF08628,PF00787; TransMembrane:2 (o62-78i83-102o); go_function: GO:0035091 - phosphatidylinositol binding [Evidence IEA]; go_function: GO:0047617 - acyl-CoA hydrolase activity [Evidence IEA] AKAW2_60705S COG:K; EggNog:ENOG410Q0CY; InterPro:IPR003173,IPR009044; PFAM:PF02229; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_60706S COG:S; EggNog:ENOG410PHHK; InterPro:IPR007330,IPR036181; PFAM:PF04212 AKAW2_60707A COG:K; EggNog:ENOG410Q127; InterPro:IPR036864,IPR001138; PFAM:PF00172; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_60709S COG:S; EggNog:ENOG410PTK2 AKAW2_60710S COG:E; EggNog:ENOG410PFW6; InterPro:IPR000994,IPR029149,IPR036005,IPR007865; MEROPS:MER0001733; PFAM:PF05195,PF00557; go_function: GO:0030145 - manganese ion binding [Evidence IEA]; go_function: GO:0070006 - metalloaminopeptidase activity [Evidence IEA] AKAW2_60711A COG:S; EggNog:ENOG410PMKS AKAW2_60712S COG:E; EggNog:ENOG410PGFF; InterPro:IPR014782,IPR016024,IPR027268,IPR038502, IPR012777,IPR001930,IPR015211,IPR034015,IPR042097; MEROPS:MER0002281; PFAM:PF01433,PF17900,PF09127; go_function: GO:0008237 - metallopeptidase activity [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006508 - proteolysis [Evidence IEA] AKAW2_60713A COG:C; EggNog:ENOG410PPQ1; InterPro:IPR021150,IPR007129; PFAM:PF03981 AKAW2_60714A BUSCO:EOG092648XW; COG:S; EggNog:ENOG410PG32; InterPro:IPR007303; PFAM:PF04176; go_process: GO:0043666 - regulation of phosphoprotein phosphatase activity [Evidence IEA] AKAW2_60715S COG:D; EggNog:ENOG410PFYF; InterPro:IPR017441,IPR008271,IPR030616,IPR000719, IPR011009; PFAM:PF07714,PF00069; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_60716A BUSCO:EOG09264RBX; COG:L; EggNog:ENOG410PMGW; InterPro:IPR019165; MEROPS:MER0127117; PFAM:PF09768; go_function: GO:0004222 - metalloendopeptidase activity [Evidence IEA] AKAW2_60717S BUSCO:EOG09262IZO; COG:E; EggNog:ENOG410PFWT; InterPro:IPR036974,IPR001048,IPR041739,IPR019797, IPR036393,IPR001057,IPR015947,IPR011529,IPR005715, IPR002478; PFAM:PF01472,PF00696; go_component: GO:0005737 - cytoplasm [Evidence IEA]; go_function: GO:0003723 - RNA binding [Evidence IEA]; go_function: GO:0004349 - glutamate 5-kinase activity [Evidence IEA]; go_process: GO:0006561 - proline biosynthetic process [Evidence IEA] AKAW2_60718A COG:S; EggNog:ENOG410PRQA; InterPro:IPR008659,IPR018466; PFAM:PF10342,PF05390; SECRETED:SignalP(1-21); go_process: GO:0006078 - (1->6)-beta-D-glucan biosynthetic process [Evidence IEA]; go_process: GO:0042546 - cell wall biogenesis [Evidence IEA] AKAW2_60719S COG:U; EggNog:ENOG410PPC5; InterPro:IPR027417,IPR019009; PFAM:PF09439; TransMembrane:1 (o23-44i) AKAW2_60720A COG:Q; EggNog:ENOG410PX3B; InterPro:IPR036291,IPR002347; PFAM:PF00106; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_60721A COG:E; EggNog:ENOG410PFT3; InterPro:IPR001216,IPR000644,IPR001926,IPR036052, IPR005857; PFAM:PF00291,PF00571; go_component: GO:0005737 - cytoplasm [Evidence IEA]; go_function: GO:0004122 - cystathionine beta-synthase activity [Evidence IEA]; go_process: GO:0006535 - cysteine biosynthetic process from serine [Evidence IEA]; go_process: GO:0019343 - cysteine biosynthetic process via cystathionine [Evidence IEA] AKAW2_60722S COG:P; EggNog:ENOG410PIQ9; InterPro:IPR004798,IPR004837; PFAM:PF01699; TransMembrane:8 (n2-10c15/16o25-44i56-78o90-112i133-151o171-192i224- 248o328-347i354-374o); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0015369 - calcium:proton antiporter activity [Evidence IEA]; go_process: GO:0006816 - calcium ion transport [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_60723S COG:S; EggNog:ENOG410PG6K AKAW2_60724S COG:S; EggNog:ENOG410PJMA; InterPro:IPR013922; PFAM:PF08613; go_function: GO:0019901 - protein kinase binding [Evidence IEA]; go_process: GO:0000079 - regulation of cyclin-dependent protein serine/threonine kinase activity [Evidence IEA] AKAW2_60725S COG:S; EggNog:ENOG410PH8P; InterPro:IPR002110,IPR036770,IPR001594,IPR020683; PFAM:PF13857,PF12796,PF00023,PF13606,PF01529; TransMembrane:5 (o311-344i365-385o397-416i495-517o550-571i); go_function: GO:0005515 - protein binding [Evidence IEA]; go_function: GO:0016409 - palmitoyltransferase activity [Evidence IEA] AKAW2_60726A COG:Q; EggNog:ENOG410QEAU; InterPro:IPR025700,IPR036188; PFAM:PF13434 AKAW2_60727S BUSCO:EOG09260W9L; COG:D; EggNog:ENOG410PVUR; InterPro:IPR000719,IPR011009,IPR008271; PFAM:PF07714,PF00069; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_60728S COG:A; EggNog:ENOG410PH2K; InterPro:IPR011709,IPR027417,IPR001650,IPR014001, IPR007502,IPR011545,IPR002464; PFAM:PF04408,PF00270,PF07717,PF00271; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0004386 - helicase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA] AKAW2_60729S COG:C; EggNog:ENOG410QDBR; InterPro:IPR036400,IPR018506,IPR001199; PFAM:PF00173; go_function: GO:0020037 - heme binding [Evidence IEA] AKAW2_60730A COG:S; EggNog:ENOG410PKA4; InterPro:IPR024774; PFAM:PF12814; go_component: GO:0005938 - cell cortex [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_function: GO:0005543 - phospholipid binding [Evidence IEA]; go_process: GO:0032065 - maintenance of protein location in cell cortex [Evidence IEA] AKAW2_60731S COG:E; EggNog:ENOG410PQK9; InterPro:IPR041492,IPR006439,IPR023198,IPR006328, IPR036412,IPR023214; PFAM:PF13419; go_function: GO:0016787 - hydrolase activity [Evidence IEA]; go_function: GO:0019120 - hydrolase activity, acting on acid halide bonds, in C-halide compounds [Evidence IEA] AKAW2_60732S COG:O; EggNog:ENOG410PKY1; InterPro:IPR036249,IPR036282,IPR010987,IPR004045, IPR016639; PFAM:PF13409,PF00043,PF13410; go_function: GO:0004364 - glutathione transferase activity [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0006749 - glutathione metabolic process [Evidence IEA] AKAW2_60733S COG:S; EggNog:ENOG410PM57; InterPro:IPR005225,IPR001806,IPR027417,IPR020849; PFAM:PF08477,PF00071; go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0003924 - GTPase activity [Evidence IEA]; go_function: GO:0005525 - GTP binding [Evidence IEA]; go_process: GO:0007165 - signal transduction [Evidence IEA] AKAW2_60734S COG:I; EggNog:ENOG410PIJN; InterPro:IPR000873,IPR020845,IPR032387,IPR042099, IPR025110; PFAM:PF00501,PF16177,PF13193 AKAW2_60735A COG:S; EggNog:ENOG410Q2ME; SECRETED:SignalP(1-18) AKAW2_60736S COG:E; EggNog:ENOG410PFHX; InterPro:IPR019798,IPR039429,IPR001085,IPR015424, IPR015421,IPR015422; PFAM:PF00464; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0004372 - glycine hydroxymethyltransferase activity [Evidence IEA]; go_function: GO:0030170 - pyridoxal phosphate binding [Evidence IEA]; go_process: GO:0019264 - glycine biosynthetic process from serine [Evidence IEA]; go_process: GO:0035999 - tetrahydrofolate interconversion [Evidence IEA] AKAW2_60737S COG:S; EggNog:ENOG410PMPV; InterPro:IPR005302,IPR005303; PFAM:PF03476,PF03473; TransMembrane:2 (i178-196o202-220i); go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0030151 - molybdenum ion binding [Evidence IEA]; go_function: GO:0030170 - pyridoxal phosphate binding [Evidence IEA] AKAW2_60738S COG:S; EggNog:ENOG410PNYZ; InterPro:IPR008136,IPR036653; PFAM:PF02464 AKAW2_60739S COG:S; EggNog:ENOG410QE5Q; InterPro:IPR016035,IPR002641; PFAM:PF01734; go_process: GO:0006629 - lipid metabolic process [Evidence IEA] AKAW2_60740S COG:S; EggNog:ENOG410PIYM; InterPro:IPR008521; PFAM:PF05653; TransMembrane:9 (o28-47i73-92o98-119i126-147o167-187i194-220o232-251i258- 284o290-311i); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0015095 - magnesium ion transmembrane transporter activity [Evidence IEA]; go_process: GO:0015693 - magnesium ion transport [Evidence IEA] AKAW2_60742S COG:L; EggNog:ENOG410Q5HX; InterPro:IPR003163,IPR036887,IPR018004,IPR029790; go_function: GO:0003677 - DNA binding [Evidence IEA] AKAW2_60743A COG:F,P; EggNog:ENOG410PVMK; InterPro:IPR000760,IPR006239; PFAM:PF00459; go_function: GO:0008441 - 3'(2'),5'-bisphosphate nucleotidase activity [Evidence IEA]; go_process: GO:0006790 - sulfur compound metabolic process [Evidence IEA]; go_process: GO:0046855 - inositol phosphate dephosphorylation [Evidence IEA] AKAW2_60744A COG:F,P; EggNog:ENOG410PG6B; InterPro:IPR005829,IPR005828,IPR003663,IPR036259, IPR020846; PFAM:PF00083,PF07690; TransMembrane:12 (i42-66o86-106i113-133o139-160i172-194o200-222i291- 313o325-346i353-375o395-418i430-451o463-484i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_60746S COG:Q; EggNog:ENOG410PUIW; InterPro:IPR001128,IPR017972,IPR002401,IPR036396; PFAM:PF00067; TransMembrane:2 (o6-28i40-58o); go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_60747S COG:C; EggNog:ENOG410PU95; InterPro:IPR001709,IPR001433,IPR001094,IPR017927, IPR023208,IPR023173,IPR029039,IPR008254,IPR017938, IPR039261,IPR003097; PFAM:PF00175,PF00258,PF00667; go_function: GO:0003958 - NADPH-hemoprotein reductase activity [Evidence IEA]; go_function: GO:0010181 - FMN binding [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_60748A COG:A; EggNog:ENOG410PGXQ; InterPro:IPR027417,IPR001650,IPR014001,IPR007502, IPR011545; PFAM:PF04408,PF00270,PF00271; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0004386 - helicase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA] AKAW2_60749S COG:J; EggNog:ENOG410QDSB; InterPro:IPR016024,IPR011989,IPR033173,IPR021133, IPR034085,IPR022716; PFAM:PF12074,PF13513; go_function: GO:0019887 - protein kinase regulator activity [Evidence IEA]; go_function: GO:0019901 - protein kinase binding [Evidence IEA]; go_function: GO:0043022 - ribosome binding [Evidence IEA]; go_process: GO:0006417 - regulation of translation [Evidence IEA]; go_process: GO:0033674 - positive regulation of kinase activity [Evidence IEA] AKAW2_60750S COG:J; EggNog:ENOG410QDSB; InterPro:IPR039547,IPR015972,IPR035970,IPR023638, IPR033935,IPR000196; PFAM:PF01280; go_component: GO:0005840 - ribosome [Evidence IEA]; go_component: GO:0022625 - cytosolic large ribosomal subunit [Evidence IEA]; go_function: GO:0003723 - RNA binding [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_process: GO:0006412 - translation [Evidence IEA] AKAW2_60751A COG:S; EggNog:ENOG410Q1A4; TransMembrane:1 (o208-232i) AKAW2_60752S COG:S; EggNog:ENOG410PJ3R AKAW2_60753A TransMembrane:2 (i29-53o73-95i) AKAW2_60755S COG:S; EggNog:ENOG410PK6N; InterPro:IPR036864,IPR001138; PFAM:PF00172; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_60756S TransMembrane:3 (o574-593i1071-1089o5826-5845i) AKAW2_60757S COG:P; EggNog:ENOG410PG66; InterPro:IPR044089,IPR002523; PFAM:PF01544; TransMembrane:2 (i841-864o876-897i); go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0015095 - magnesium ion transmembrane transporter activity [Evidence IEA]; go_function: GO:0046873 - metal ion transmembrane transporter activity [Evidence IEA]; go_process: GO:0030001 - metal ion transport [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA]; go_process: GO:1903830 - magnesium ion transmembrane transport [Evidence IEA] AKAW2_60758S COG:S; EggNog:ENOG410PFAC; InterPro:IPR024260; PFAM:PF12751; TransMembrane:1 (i626-649o) AKAW2_60759A COG:S; EggNog:ENOG410PS6R; InterPro:IPR024436; TransMembrane:2 (o289-307i383-404o) AKAW2_60761S COG:S; EggNog:ENOG410PM8B; InterPro:IPR007219; PFAM:PF04082; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA] AKAW2_60762A COG:G; EggNog:ENOG410PK2K; InterPro:IPR005828,IPR003663,IPR036259,IPR020846; PFAM:PF00083,PF07690; TransMembrane:11 (n3-14c32/33o48-69i81-102o108-124i136-156o168-190i255- 276o288-310i322-339o351-370i391-409o421-440i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_60763A BUSCO:EOG09265JX6; COG:J; EggNog:ENOG410PPND; InterPro:IPR000552,IPR011332; PFAM:PF00935; go_component: GO:0005840 - ribosome [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_process: GO:0006412 - translation [Evidence IEA] AKAW2_60764A COG:S; EggNog:ENOG410Q2AA; InterPro:IPR009097 AKAW2_60765A COG:K; EggNog:ENOG410PQMJ; InterPro:IPR010684; PFAM:PF06881; go_component: GO:0005634 - nucleus [Evidence IEA]; go_component: GO:0070449 - elongin complex [Evidence IEA]; go_process: GO:0006368 - transcription elongation from RNA polymerase II promoter [Evidence IEA] AKAW2_60766S COG:U,Z; EggNog:ENOG410PKAY; InterPro:IPR001107,IPR027705,IPR036013; PFAM:PF01145 AKAW2_60767S COG:S; EggNog:ENOG410PSB5; InterPro:IPR036126,IPR004226; PFAM:PF02970; go_function: GO:0048487 - beta-tubulin binding [Evidence IEA]; go_process: GO:0007021 - tubulin complex assembly [Evidence IEA]; go_process: GO:0007023 - post-chaperonin tubulin folding pathway [Evidence IEA] AKAW2_60768A COG:S; EggNog:ENOG410PIZ9; InterPro:IPR008501; PFAM:PF05615; go_component: GO:0000445 - THO complex part of transcription export complex [Evidence IEA]; go_process: GO:0006397 - mRNA processing [Evidence IEA] AKAW2_60769S COG:S; EggNog:ENOG410PXCR; InterPro:IPR004332; PFAM:PF03108 AKAW2_60770S COG:G; EggNog:ENOG410PIWG; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690,PF06609; TransMembrane:14 (i20-40o60-78i90-110o116-137i149-173o179-199i220-241o247- 265i285-306o318-340i352-370o376-401i422-440o483-501i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_60771S COG:S; EggNog:ENOG410PIT7; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; TransMembrane:1 (o547-569i); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_60772A COG:O; EggNog:ENOG410PH66; InterPro:IPR008971,IPR002939,IPR001623,IPR036869, IPR001305,IPR036410; PFAM:PF00684,PF00226,PF01556; SECRETED:SignalP(1-24); go_function: GO:0031072 - heat shock protein binding [Evidence IEA]; go_function: GO:0051082 - unfolded protein binding [Evidence IEA]; go_process: GO:0006457 - protein folding [Evidence IEA] AKAW2_60773A COG:S; EggNog:ENOG410PGVT; InterPro:IPR027842,IPR017943; go_function: GO:0008289 - lipid binding [Evidence IEA] AKAW2_60774S COG:C; EggNog:ENOG410PGTW; InterPro:IPR036291,IPR012301,IPR012302,IPR001891, IPR015884,IPR037062; PFAM:PF00390,PF03949; go_function: GO:0004470 - malic enzyme activity [Evidence IEA]; go_function: GO:0004471 - malate dehydrogenase (decarboxylating) (NAD+) activity [Evidence IEA]; go_function: GO:0051287 - NAD binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_60775S COG:C; EggNog:ENOG410PN40; InterPro:IPR001155,IPR013785; PFAM:PF00724; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0010181 - FMN binding [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_60776S COG:A; EggNog:ENOG410PMW5; InterPro:IPR022801,IPR001912; PFAM:PF00163; TransMembrane:1 (i129-147o); go_function: GO:0019843 - rRNA binding [Evidence IEA] AKAW2_60777A COG:S; EggNog:ENOG410PXYE AKAW2_60779A COG:G; EggNog:ENOG410PI9I; InterPro:IPR011701,IPR036259; PFAM:PF07690; TransMembrane:10 (i64-82o136-154i161-181o201-220i232-252o336-357i364- 387o393-413i425-446o458-478i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_60780A BUSCO:EOG09263Q7N; COG:F; EggNog:ENOG410PFIV; InterPro:IPR011060,IPR014732,IPR018089,IPR013785, IPR001754; PFAM:PF00215; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0004590 - orotidine-5'-phosphate decarboxylase activity [Evidence IEA]; go_process: GO:0006207 - 'de novo' pyrimidine nucleobase biosynthetic process [Evidence IEA]; go_process: GO:0044205 - 'de novo' UMP biosynthetic process [Evidence IEA] AKAW2_60781A COG:O; EggNog:ENOG410PS21; InterPro:IPR023352,IPR001129; PFAM:PF01124; TransMembrane:3 (o12-32i81-104o124-145i) AKAW2_60782A COG:I; EggNog:ENOG410PHMB; InterPro:IPR014371,IPR027251,IPR004299; PFAM:PF03062; TransMembrane:8 (o82-101i122-143o178-204i295-314o344-363i406-427o439- 458i470-496o); go_function: GO:0004144 - diacylglycerol O-acyltransferase activity [Evidence IEA]; go_function: GO:0008374 - O-acyltransferase activity [Evidence IEA]; go_process: GO:0019432 - triglyceride biosynthetic process [Evidence IEA] AKAW2_60783S BUSCO:EOG09261LPY; COG:A; EggNog:ENOG410PG1Z; InterPro:IPR015943,IPR001680,IPR036322,IPR017986; PFAM:PF00400; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_60784A COG:S; EggNog:ENOG410PQYI; InterPro:IPR019334; PFAM:PF10190; TransMembrane:3 (o43-63i75-100o112-132i) AKAW2_60785S COG:S; EggNog:ENOG410PFSP; InterPro:IPR030476 AKAW2_60786A COG:O; EggNog:ENOG410PJHF; InterPro:IPR007269,IPR025770; PFAM:PF04191,PF04140; TransMembrane:5 (o58-80i87-104o165-184i205-226o232-251i); go_component: GO:0005783 - endoplasmic reticulum [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0004671 - protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity [Evidence IEA]; go_process: GO:0006481 - C-terminal protein methylation [Evidence IEA] AKAW2_60787S COG:E; EggNog:ENOG410PN3K; InterPro:IPR024688,IPR018357,IPR011004,IPR001451; PFAM:PF14602,PF00132,PF12464; go_function: GO:0016407 - acetyltransferase activity [Evidence IEA]; go_function: GO:0016740 - transferase activity [Evidence IEA] AKAW2_60788S COG:O; EggNog:ENOG410PHVX; InterPro:IPR038765,IPR021905,IPR001394,IPR018200, IPR028889; MEROPS:MER0185433; PFAM:PF12030,PF00443,PF13423; go_function: GO:0004843 - thiol-dependent ubiquitin-specific protease activity [Evidence IEA]; go_process: GO:0006511 - ubiquitin-dependent protein catabolic process [Evidence IEA]; go_process: GO:0016579 - protein deubiquitination [Evidence IEA] AKAW2_60789A COG:K; EggNog:ENOG410PI31; InterPro:IPR024550,IPR039997,IPR002853,IPR017919; PFAM:PF02002; go_process: GO:0006367 - transcription initiation from RNA polymerase II promoter [Evidence IEA] AKAW2_60790S COG:J; EggNog:ENOG410PGFR; InterPro:IPR020103,IPR020095,IPR020097,IPR041708, IPR001406; PFAM:PF01416; go_function: GO:0003723 - RNA binding [Evidence IEA]; go_function: GO:0009982 - pseudouridine synthase activity [Evidence IEA]; go_process: GO:0001522 - pseudouridine synthesis [Evidence IEA]; go_process: GO:0009451 - RNA modification [Evidence IEA]; go_process: GO:0031119 - tRNA pseudouridine synthesis [Evidence IEA] AKAW2_60791A COG:U; EggNog:ENOG410PY0X; TransMembrane:2 (i128-151o157-183i) AKAW2_60792A COG:L; EggNog:ENOG410Q051 AKAW2_60794A COG:T; EggNog:ENOG410PJ4Z; InterPro:IPR001849,IPR012966,IPR011993; PFAM:PF08174,PF00169 AKAW2_60795S COG:L; EggNog:ENOG410PIDU; InterPro:IPR027417,IPR001650,IPR014014,IPR014001, IPR011545; PFAM:PF04851,PF00270,PF00271; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0004386 - helicase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA] AKAW2_60796A COG:T; EggNog:ENOG410PF9S; InterPro:IPR019826,IPR002018,IPR029058; MEROPS:MER0033198; PFAM:PF00135; SECRETED:SignalP(1-21) AKAW2_60797A COG:B; EggNog:ENOG410PGJB; InterPro:IPR025783,IPR001214,IPR039977; go_function: GO:0005515 - protein binding [Evidence IEA]; go_function: GO:0042799 - histone methyltransferase activity (H4-K20 specific) [Evidence IEA]; go_process: GO:0034770 - histone H4-K20 methylation [Evidence IEA] AKAW2_60798S BUSCO:EOG09265HP0; COG:J; EggNog:ENOG410PPNT; InterPro:IPR000218,IPR019972,IPR005745,IPR036853; PFAM:PF00238; go_component: GO:0005840 - ribosome [Evidence IEA]; go_component: GO:0015934 - large ribosomal subunit [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_process: GO:0006412 - translation [Evidence IEA] AKAW2_60799A BUSCO:EOG092654O3; COG:K; EggNog:ENOG410PQ51; InterPro:IPR001529,IPR012164,IPR001222,IPR034012; PFAM:PF01096,PF02150; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006379 - mRNA cleavage [Evidence IEA] AKAW2_60800S BUSCO:EOG09264PI4; COG:O; EggNog:ENOG410PP19; InterPro:IPR000297,IPR036020,IPR001202; PFAM:PF00397,PF13616,PF00639; go_function: GO:0003755 - peptidyl-prolyl cis-trans isomerase activity [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_60802A COG:S; EggNog:ENOG410PISX; InterPro:IPR037700; go_function: GO:0017056 - structural constituent of nuclear pore [Evidence IEA]; go_process: GO:0000055 - ribosomal large subunit export from nucleus [Evidence IEA]; go_process: GO:0000056 - ribosomal small subunit export from nucleus [Evidence IEA]; go_process: GO:0006913 - nucleocytoplasmic transport [Evidence IEA] AKAW2_60803S BUSCO:EOG09264G04; COG:A; EggNog:ENOG410PN15; InterPro:IPR000504,IPR027157,IPR035979,IPR034148, IPR012677; PFAM:PF00076; go_component: GO:0005846 - nuclear cap binding complex [Evidence IEA]; go_function: GO:0000339 - RNA cap binding [Evidence IEA]; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_process: GO:0045292 - mRNA cis splicing, via spliceosome [Evidence IEA] AKAW2_60804A COG:H; EggNog:ENOG410PITY; InterPro:IPR002161,IPR021196,IPR029062; MEROPS:MER0066916; PFAM:PF01174; go_function: GO:0004359 - glutaminase activity [Evidence IEA]; go_process: GO:0042819 - vitamin B6 biosynthetic process [Evidence IEA]; go_process: GO:0042823 - pyridoxal phosphate biosynthetic process [Evidence IEA] AKAW2_60805S COG:S; EggNog:ENOG410PW76; InterPro:IPR037143,IPR008278; PFAM:PF01648; go_function: GO:0000287 - magnesium ion binding [Evidence IEA]; go_function: GO:0008897 - holo-[acyl-carrier-protein] synthase activity [Evidence IEA] AKAW2_60806A COG:I; EggNog:ENOG410PMHM; InterPro:IPR004552,IPR002123; PFAM:PF01553; TransMembrane:3 (i59-78o141-163i175-196o); go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0003841 - 1-acylglycerol-3-phosphate O-acyltransferase activity [Evidence IEA]; go_function: GO:0016746 - transferase activity, transferring acyl groups [Evidence IEA]; go_process: GO:0008654 - phospholipid biosynthetic process [Evidence IEA] AKAW2_60807A COG:D; EggNog:ENOG410PIGR; InterPro:IPR011990,IPR019734,IPR013026,IPR001440; PFAM:PF07719,PF00515,PF13181,PF12895,PF13432, PF14559; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_60808S BUSCO:EOG092658ZO; COG:S; EggNog:ENOG410PQTC; InterPro:IPR008506; PFAM:PF05620; TransMembrane:2 (i21-38o114-132i) AKAW2_60809A COG:S; EggNog:ENOG410PIZ7; TransMembrane:1 (i35-54o) AKAW2_60810S BUSCO:EOG09260DFJ; COG:O; EggNog:ENOG410PHMD; InterPro:IPR013083,IPR011016; PFAM:PF12906; TransMembrane:17 (o124-143i289-308o730-751i763-786o792-813i938-960o966- 986i1016-1043o1063-1081i1122-1148o1154-1175i1324- 1349o1369-1386i1421-1446o1466-1486i1507-1532o1552-1570i); go_function: GO:0008270 - zinc ion binding [Evidence IEA] AKAW2_60811S COG:S; EggNog:ENOG410PH2D; InterPro:IPR000719,IPR011009; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_60812A BUSCO:EOG092600T4; COG:I; EggNog:ENOG410PH59; InterPro:IPR029045,IPR016185,IPR013815,IPR034733, IPR011763,IPR000089,IPR011761,IPR013537,IPR011764, IPR005479,IPR005482,IPR005481,IPR011762,IPR011054, IPR011053,IPR001882; PFAM:PF02786,PF00364,PF02785,PF08326,PF01039; go_function: GO:0003989 - acetyl-CoA carboxylase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016874 - ligase activity [Evidence IEA]; go_function: GO:0046872 - metal ion binding [Evidence IEA]; go_process: GO:0006633 - fatty acid biosynthetic process [Evidence IEA] AKAW2_60813A COG:Z; EggNog:ENOG410PIRG; InterPro:IPR006964,IPR033494; PFAM:PF04880; go_process: GO:2000574 - regulation of microtubule motor activity [Evidence IEA] AKAW2_60814S InterPro:IPR022190; PFAM:PF12511 AKAW2_60815S COG:S; EggNog:ENOG410PKWK; InterPro:IPR000868,IPR036380; PFAM:PF00857 AKAW2_60816A BUSCO:EOG09265GGX; COG:U; EggNog:ENOG410PNM4; InterPro:IPR011012,IPR006722; PFAM:PF04628; go_process: GO:0006888 - endoplasmic reticulum to Golgi vesicle-mediated transport [Evidence IEA] AKAW2_60817S COG:S; EggNog:ENOG410PQ4R; InterPro:IPR018612; PFAM:PF09745 AKAW2_60818A COG:P; EggNog:ENOG410PITS; InterPro:IPR003689; PFAM:PF02535; TransMembrane:8 (o12-33i45-67o87-106i311-328o348-371i378-401o416-438i450- 468o); go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0046873 - metal ion transmembrane transporter activity [Evidence IEA]; go_process: GO:0030001 - metal ion transport [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_60820S COG:S; EggNog:ENOG410Q1GZ AKAW2_60822S BUSCO:EOG092645MK; COG:F; EggNog:ENOG410PHAY; InterPro:IPR040255,IPR020821,IPR018524,IPR001604; PFAM:PF01223; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0016787 - hydrolase activity [Evidence IEA]; go_function: GO:0046872 - metal ion binding [Evidence IEA] AKAW2_60823A COG:O; EggNog:ENOG410PM5D; InterPro:IPR001841,IPR027370,IPR017907,IPR016818, IPR013083; PFAM:PF13445; go_function: GO:0061630 - ubiquitin protein ligase activity [Evidence IEA] AKAW2_60824A TransMembrane:2 (i7-35o55-76i) AKAW2_60825A COG:U; EggNog:ENOG410PJIX; InterPro:IPR035999,IPR011993,IPR023394,IPR000904, IPR001849; PFAM:PF00169,PF01369; go_function: GO:0005086 - ARF guanyl-nucleotide exchange factor activity [Evidence IEA]; go_process: GO:0032012 - regulation of ARF protein signal transduction [Evidence IEA] AKAW2_60826S COG:E; EggNog:ENOG410PF8X; InterPro:IPR000834; MEROPS:MER0003908; PFAM:PF00246; SECRETED:SignalP(1-20); go_function: GO:0004181 - metallocarboxypeptidase activity [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006508 - proteolysis [Evidence IEA] AKAW2_60827A COG:E; EggNog:ENOG410PG5H; InterPro:IPR004840,IPR004841; PFAM:PF13520,PF00324; TransMembrane:11 (o47-69i76-101o128-150i157-176o188-208i279-300o320- 345i380-397o409-432i452-473o493-510i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_process: GO:0006865 - amino acid transport [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_60828A COG:Q; EggNog:ENOG410PH0S; InterPro:IPR017871,IPR027417,IPR003593,IPR011527, IPR003439,IPR036640; PFAM:PF00005,PF00664; TransMembrane:14 (o30-50i62-82o88-109i118-142o229-251i263-280o286-306i347- 366o372-389i455-475o806-826i870-892o952-981i1052-1073o); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA]; go_function: GO:0042626 - ATPase-coupled transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_60829S COG:Q; EggNog:ENOG410Q1EP; InterPro:IPR036396,IPR001128,IPR002401; PFAM:PF00067; TransMembrane:1 (o12-36i); go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_60830S COG:Q; EggNog:ENOG410PIVB; InterPro:IPR002347,IPR036291,IPR020904; PFAM:PF00106,PF13561,PF08659; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_60831S COG:S; EggNog:ENOG410Q2S2 AKAW2_60832S COG:M; EggNog:ENOG410PG00; InterPro:IPR002110,IPR036770,IPR020683; PFAM:PF12796,PF00023,PF13637,PF13606; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_60833S CAZy:CE10; COG:I; EggNog:ENOG410PR6J; InterPro:IPR029058,IPR013094; PFAM:PF07859; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_60834A COG:V; EggNog:ENOG410PGQ5; InterPro:IPR036291,IPR001509; PFAM:PF01073,PF01370; go_function: GO:0003824 - catalytic activity [Evidence IEA] AKAW2_60835A COG:Q; EggNog:ENOG410PMRI; InterPro:IPR001128,IPR017972,IPR002401,IPR036396; PFAM:PF00067; TransMembrane:1 (o6-27i); go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_60836S COG:T; EggNog:ENOG410PJPI; InterPro:IPR019819,IPR019826,IPR002018,IPR029058; MEROPS:MER0030934; PFAM:PF00135 AKAW2_60838S COG:S; EggNog:ENOG410PNQ3 AKAW2_60840S COG:P; EggNog:ENOG410PK7C; InterPro:IPR011541,IPR004688; PFAM:PF03824; TransMembrane:8 (i52-79o129-149i161-184o204-221i233-255o261-280i331- 358o378-401i); go_component: GO:0005887 - integral component of plasma membrane [Evidence IEA]; go_function: GO:0015099 - nickel cation transmembrane transporter activity [Evidence IEA]; go_process: GO:0035444 - nickel cation transmembrane transport [Evidence IEA] AKAW2_60841A CAZy:CE4; COG:G; EggNog:ENOG410PP58; InterPro:IPR002509,IPR011330; PFAM:PF01522; SECRETED:SignalP(1-19); go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0016810 - hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_60842S COG:L; EggNog:ENOG410PJ3I; InterPro:IPR018944,IPR022312,IPR001357,IPR027421, IPR043519,IPR019843,IPR002008,IPR029398,IPR028207, IPR037160,IPR002054; PFAM:PF10391,PF14791,PF14792; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0003887 - DNA-directed DNA polymerase activity [Evidence IEA]; go_function: GO:0016779 - nucleotidyltransferase activity [Evidence IEA]; go_function: GO:0034061 - DNA polymerase activity [Evidence IEA]; go_process: GO:0006281 - DNA repair [Evidence IEA] AKAW2_60843A COG:P; EggNog:ENOG410QE8C; InterPro:IPR018303,IPR023298,IPR023299,IPR001757, IPR032630,IPR006539,IPR036412,IPR008250,IPR023214, IPR032631; PFAM:PF13246,PF16209,PF00702,PF16212; TransMembrane:9 (o297-316i497-520o547-568i1059-1079o1099-1121i1142- 1166o1178-1195i1207-1230o1250-1269i); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0000166 - nucleotide binding [Evidence IEA]; go_function: GO:0000287 - magnesium ion binding [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0140326 - ATPase-coupled intramembrane lipid transporter activity [Evidence IEA]; go_process: GO:0015914 - phospholipid transport [Evidence IEA] AKAW2_60845S COG:S; EggNog:ENOG410PYZ0; InterPro:IPR001810,IPR036047; PFAM:PF00646; SECRETED:SignalP(1-23); go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_60844A COG:Q; EggNog:ENOG410PHH6; InterPro:IPR001128,IPR002401,IPR036396; PFAM:PF00067; TransMembrane:2 (n24-37c42/43o52-74i86-107o); go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_60846S CAZy:AA3; COG:E; EggNog:ENOG410PVHT; InterPro:IPR012132,IPR036188,IPR000172,IPR007867; PFAM:PF05199,PF00732; go_function: GO:0016614 - oxidoreductase activity, acting on CH-OH group of donors [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_60847A COG:S; EggNog:ENOG410Q21K; InterPro:IPR011009 AKAW2_60848A BUSCO:EOG09264398; COG:J; EggNog:ENOG410PFQI; InterPro:IPR033100,IPR015847,IPR020568,IPR027408, IPR001247,IPR036345; PFAM:PF01138,PF03725; go_component: GO:0000178 - exosome (RNase complex) [Evidence IEA]; go_process: GO:0006396 - RNA processing [Evidence IEA] AKAW2_60849S COG:A; EggNog:ENOG410PN2P; InterPro:IPR006973; PFAM:PF04889; go_component: GO:0005681 - spliceosomal complex [Evidence IEA]; go_process: GO:0000398 - mRNA splicing, via spliceosome [Evidence IEA] AKAW2_60850S COG:S; EggNog:ENOG410PTCK; InterPro:IPR038427,IPR009332; PFAM:PF06179; go_component: GO:0016592 - mediator complex [Evidence IEA]; go_function: GO:0003712 - transcription coregulator activity [Evidence IEA]; go_process: GO:0006357 - regulation of transcription by RNA polymerase II [Evidence IEA] AKAW2_60851S COG:H; EggNog:ENOG410PPTW; InterPro:IPR001796,IPR024072,IPR017925,IPR012259; PFAM:PF00186; go_function: GO:0004146 - dihydrofolate reductase activity [Evidence IEA]; go_function: GO:0050661 - NADP binding [Evidence IEA]; go_process: GO:0006545 - glycine biosynthetic process [Evidence IEA]; go_process: GO:0046654 - tetrahydrofolate biosynthetic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_60852A COG:P; EggNog:ENOG410PFDT; InterPro:IPR001807,IPR014743; PFAM:PF00654; TransMembrane:10 (i188-213o267-290i376-393o399-415i427-451o463-480i501- 522o542-562i601-619o625-649i); go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0005247 - voltage-gated chloride channel activity [Evidence IEA]; go_process: GO:0006821 - chloride transport [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_60853S CAZy:AA9; COG:G; EggNog:ENOG410PNFI; InterPro:IPR005103; PFAM:PF03443; SECRETED:SignalP(1-22) AKAW2_60854S COG:S; EggNog:ENOG410PIYI; InterPro:IPR011118,IPR029058; PFAM:PF07519; SECRETED:SignalP(1-27) AKAW2_60855S COG:I; EggNog:ENOG410PMS4; InterPro:IPR013830,IPR036514; PFAM:PF00657,PF13472 AKAW2_60856S COG:S; EggNog:ENOG410PKPH AKAW2_60857A COG:Q; EggNog:ENOG410PP10; InterPro:IPR000868,IPR036380; PFAM:PF00857 AKAW2_60858A BUSCO:EOG09263GIG; COG:H; EggNog:ENOG410PFZZ; InterPro:IPR029056,IPR000417,IPR036206,IPR022998, IPR034291,IPR013785; PFAM:PF02110,PF02581; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0004417 - hydroxyethylthiazole kinase activity [Evidence IEA]; go_function: GO:0004789 - thiamine-phosphate diphosphorylase activity [Evidence IEA]; go_process: GO:0009228 - thiamine biosynthetic process [Evidence IEA] AKAW2_60859S BUSCO:EOG09262M7B; COG:J; EggNog:ENOG410PGC2; InterPro:IPR003307,IPR016021,IPR016189,IPR016190, IPR016024,IPR002735; PFAM:PF02020,PF01873; go_function: GO:0003743 - translation initiation factor activity [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0006413 - translational initiation [Evidence IEA] AKAW2_60860A BUSCO:EOG09260KGS; COG:S; EggNog:ENOG410PK3J; InterPro:IPR016024 AKAW2_60861S COG:L; EggNog:ENOG410PFUW; InterPro:IPR012308,IPR012309,IPR036599,IPR000977, IPR016059,IPR012310,IPR012340; PFAM:PF04675,PF01068,PF04679; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0003909 - DNA ligase activity [Evidence IEA]; go_function: GO:0003910 - DNA ligase (ATP) activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006281 - DNA repair [Evidence IEA]; go_process: GO:0006310 - DNA recombination [Evidence IEA]; go_process: GO:0051103 - DNA ligation involved in DNA repair [Evidence IEA]; go_process: GO:0071897 - DNA biosynthetic process [Evidence IEA] AKAW2_60862S COG:O; EggNog:ENOG410PHIG; InterPro:IPR001375,IPR029058; MEROPS:MER0000263; PFAM:PF00326; SECRETED:SignalP(1-19); go_function: GO:0008236 - serine-type peptidase activity [Evidence IEA]; go_process: GO:0006508 - proteolysis [Evidence IEA] AKAW2_60863A BUSCO:EOG09260KCW; COG:P; EggNog:ENOG410PFXZ; InterPro:IPR003807,IPR018966,IPR004331; PFAM:PF09359,PF02656; TransMembrane:3 (o697-715i727-746o766-785i) AKAW2_60864A COG:L; EggNog:ENOG410PHQM; InterPro:IPR027417,IPR001208,IPR041562,IPR027925, IPR033762,IPR008047,IPR031327,IPR012340,IPR018525; PFAM:PF00493,PF17855,PF17207,PF07728,PF14551; go_component: GO:0042555 - MCM complex [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0003678 - DNA helicase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006260 - DNA replication [Evidence IEA]; go_process: GO:0006270 - DNA replication initiation [Evidence IEA]; go_process: GO:0032508 - DNA duplex unwinding [Evidence IEA] AKAW2_60865S COG:S; EggNog:ENOG410PG2J; InterPro:IPR003864,IPR027815,IPR032880,IPR022257; PFAM:PF12621,PF02714,PF13967; TransMembrane:11 (o24-48i108-127o168-187i662-686o706-732i753-781o801- 829i850-869o875-893i914-935o947-965i); go_component: GO:0016020 - membrane [Evidence IEA] AKAW2_60866A BUSCO:EOG09262N47; COG:E; EggNog:ENOG410PI10; InterPro:IPR026480,IPR017408,IPR029063,IPR036770; go_function: GO:0016274 - protein-arginine N-methyltransferase activity [Evidence IEA] AKAW2_60867A COG:O; EggNog:ENOG410PH8R; InterPro:IPR001107,IPR000163,IPR036013; PFAM:PF01145; go_component: GO:0016020 - membrane [Evidence IEA] AKAW2_60868S COG:A; EggNog:ENOG410PMBW; InterPro:IPR000504,IPR035979,IPR026896,IPR012677, IPR025742,IPR038192; PFAM:PF14327,PF14304,PF00076; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_process: GO:0031124 - mRNA 3'-end processing [Evidence IEA] AKAW2_60870S COG:L; EggNog:ENOG410PFXX; InterPro:IPR001525,IPR029063; PFAM:PF00145; go_function: GO:0008168 - methyltransferase activity [Evidence IEA] AKAW2_60871S COG:L; EggNog:ENOG410PFXX; InterPro:IPR038718,IPR017907,IPR000330,IPR027417, IPR001650,IPR014001; go_function: GO:0005524 - ATP binding [Evidence IEA] AKAW2_60872A COG:C; EggNog:ENOG410PFVJ; InterPro:IPR042128,IPR036249,IPR002023,IPR041921; PFAM:PF01257; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_60873A COG:S; EggNog:ENOG410PSWE; InterPro:IPR036069,IPR015867 AKAW2_60874A COG:F; EggNog:ENOG410PGAZ; InterPro:IPR001365,IPR028892,IPR006330,IPR032466, IPR006650; PFAM:PF00962; go_function: GO:0000034 - adenine deaminase activity [Evidence IEA]; go_function: GO:0019239 - deaminase activity [Evidence IEA]; go_process: GO:0006146 - adenine catabolic process [Evidence IEA]; go_process: GO:0009168 - purine ribonucleoside monophosphate biosynthetic process [Evidence IEA] AKAW2_60875A COG:S; EggNog:ENOG410PJW4; InterPro:IPR036291,IPR001509; TransMembrane:1 (o6-24i); go_function: GO:0003824 - catalytic activity [Evidence IEA] AKAW2_60876A BUSCO:EOG09262FW1; COG:J; EggNog:ENOG410PG3Z; InterPro:IPR010923,IPR017945,IPR005145,IPR006070, IPR038385; PFAM:PF03481,PF01300; go_function: GO:0003725 - double-stranded RNA binding [Evidence IEA] AKAW2_60877A COG:U; EggNog:ENOG410Q113; InterPro:IPR008532,IPR021846; PFAM:PF11923,PF05670,PF05833 AKAW2_60878A BUSCO:EOG09264OBA; COG:U; EggNog:ENOG410PJAW; InterPro:IPR022775,IPR011012,IPR039652; PFAM:PF01217; go_component: GO:0030126 - COPI vesicle coat [Evidence IEA]; go_process: GO:0006890 - retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [Evidence IEA] AKAW2_60879A COG:S; EggNog:ENOG410PGDP AKAW2_60880S COG:J; EggNog:ENOG410PPNR; InterPro:IPR004038,IPR029064,IPR039109,IPR022991; PFAM:PF01248; go_function: GO:0003723 - RNA binding [Evidence IEA] AKAW2_60881S COG:S; EggNog:ENOG410PMNC AKAW2_60882S TransMembrane:1 (i28-48o) AKAW2_60883S COG:S; EggNog:ENOG410PW0T; InterPro:IPR000073,IPR029058; PFAM:PF12697 AKAW2_60884A COG:A; EggNog:ENOG410PIUS; InterPro:IPR011709,IPR027417,IPR007502,IPR014001, IPR001650,IPR002464; PFAM:PF04408,PF07717,PF00271; go_function: GO:0004386 - helicase activity [Evidence IEA] AKAW2_60885A BUSCO:EOG09261FAB; COG:S; EggNog:ENOG410PHB3; InterPro:IPR001810,IPR036047; PFAM:PF00646,PF12937; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_60886S BUSCO:EOG09262JAT; COG:C; EggNog:ENOG410PH71; InterPro:IPR018108,IPR023395; PFAM:PF00153 AKAW2_60887S COG:S; EggNog:ENOG410PKMX; InterPro:IPR007751,IPR029058,IPR039182; go_component: GO:0000172 - ribonuclease MRP complex [Evidence IEA]; go_component: GO:0005655 - nucleolar ribonuclease P complex [Evidence IEA]; go_process: GO:0001682 - tRNA 5'-leader removal [Evidence IEA] AKAW2_60888S COG:S; EggNog:ENOG410PKMX; InterPro:IPR002523,IPR039182; PFAM:PF01544; TransMembrane:3 (o585-607i619-643o658-678i); go_component: GO:0000172 - ribonuclease MRP complex [Evidence IEA]; go_component: GO:0005655 - nucleolar ribonuclease P complex [Evidence IEA]; go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0046873 - metal ion transmembrane transporter activity [Evidence IEA]; go_process: GO:0001682 - tRNA 5'-leader removal [Evidence IEA]; go_process: GO:0030001 - metal ion transport [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_60889A BUSCO:EOG09261J0P; COG:O; EggNog:ENOG410PHYR; InterPro:IPR002423,IPR001844,IPR027410,IPR027413, IPR027409,IPR018370; PFAM:PF00118; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006457 - protein folding [Evidence IEA]; go_process: GO:0042026 - protein refolding [Evidence IEA] AKAW2_60890S COG:C; EggNog:ENOG410PS16; InterPro:IPR036742,IPR006721; PFAM:PF04627; go_component: GO:0000275 - mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1) [Evidence IEA]; go_function: GO:0046933 - proton-transporting ATP synthase activity, rotational mechanism [Evidence IEA]; go_process: GO:0015986 - ATP synthesis coupled proton transport [Evidence IEA] AKAW2_60891S BUSCO:EOG09261IFQ; COG:S; EggNog:ENOG410PH4J; InterPro:IPR007244; PFAM:PF04112; TransMembrane:1 (o574-595i); go_component: GO:0031417 - NatC complex [Evidence IEA]; go_process: GO:0017196 - N-terminal peptidyl-methionine acetylation [Evidence IEA] AKAW2_60892S COG:K; EggNog:ENOG410PKPQ; InterPro:IPR036864,IPR004507,IPR001138; PFAM:PF00172; TransMembrane:1 (o305-325i); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_60893S COG:K; EggNog:ENOG410PKPQ; InterPro:IPR004507 AKAW2_60895S COG:Q; EggNog:ENOG410PXEJ; InterPro:IPR002347,IPR036291,IPR020904; PFAM:PF00106,PF13561,PF08659; TransMembrane:1 (i12-31o); go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_60894A COG:Q; EggNog:ENOG410PFPW; InterPro:IPR015798,IPR016182,IPR036460,IPR000269, IPR015800,IPR015328; PFAM:PF01179,PF02727,PF09248; go_function: GO:0005507 - copper ion binding [Evidence IEA]; go_function: GO:0008131 - primary amine oxidase activity [Evidence IEA]; go_function: GO:0048038 - quinone binding [Evidence IEA]; go_process: GO:0009308 - amine metabolic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_60896S COG:Q; EggNog:ENOG410PWMI; InterPro:IPR020946,IPR036188; PFAM:PF07992,PF13738,PF13450; go_function: GO:0004499 - N,N-dimethylaniline monooxygenase activity [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_function: GO:0050661 - NADP binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_60897S CAZy:CE1; COG:O; EggNog:ENOG410PI6W; InterPro:IPR010126,IPR029058; PFAM:PF00326,PF10503; SECRETED:SignalP(1-24); go_component: GO:0005576 - extracellular region [Evidence IEA]; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_60898A SECRETED:SignalP(1-16) AKAW2_60899S COG:M,O,T; EggNog:ENOG410PGAV; InterPro:IPR011990,IPR006597; PFAM:PF08238; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_60900S COG:S; EggNog:ENOG410PUVK; InterPro:IPR036236,IPR013087,IPR007219; PFAM:PF04082; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA] AKAW2_60901A COG:G; EggNog:ENOG410PVTK; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i61-78o102-124i131-152o158-180i192-213o225-247i297- 318o330-353i360-382o388-409i421-443o449-472i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_60902S COG:G; EggNog:ENOG410PJK5; InterPro:IPR005000,IPR015813,IPR040442; PFAM:PF03328; go_function: GO:0003824 - catalytic activity [Evidence IEA] AKAW2_60903A COG:J; EggNog:ENOG410PWSZ; InterPro:IPR006175,IPR035959; PFAM:PF01042 AKAW2_60904S COG:Q; EggNog:ENOG410PU9J; InterPro:IPR026992,IPR027443,IPR005123; PFAM:PF03171,PF14226; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_60905A COG:Q; EggNog:ENOG410PNBN; InterPro:IPR002347,IPR036291,IPR020904; PFAM:PF00106,PF13561,PF08659,PF01370; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_60906S COG:S; EggNog:ENOG410PQ8T; InterPro:IPR032675 AKAW2_60907S COG:T; EggNog:ENOG410PQEF; InterPro:IPR000719,IPR011009,IPR008271; PFAM:PF07714,PF00069; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_60908A COG:Q; EggNog:ENOG410PIXU; InterPro:IPR015889; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016702 - oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_60909A COG:C; EggNog:ENOG410QDJM; InterPro:IPR039556,IPR015813,IPR040442; PFAM:PF13714; go_function: GO:0003824 - catalytic activity [Evidence IEA] AKAW2_60910S COG:G; EggNog:ENOG410QDHJ; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690,PF00083; TransMembrane:12 (i45-62o88-107i114-133o145-164i176-195o207-227i275- 294o314-331i338-356o368-390i402-423o429-452i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_60911S COG:S; EggNog:ENOG410QE3U; InterPro:IPR036864,IPR001138; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_60912A COG:Q; EggNog:ENOG410Q2WX; InterPro:IPR001613,IPR036188,IPR002937; PFAM:PF13450,PF01593; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_60913S COG:K; EggNog:ENOG410PMRV; InterPro:IPR007219; TransMembrane:2 (i91-111o140-160i); go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA] AKAW2_60914S COG:S; EggNog:ENOG410PIY1; InterPro:IPR005123; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_60915A COG:S; EggNog:ENOG410PJ82; InterPro:IPR036291,IPR008030; PFAM:PF05368 AKAW2_60916S COG:G,M; EggNog:ENOG410PW89; InterPro:IPR036291,IPR008030; PFAM:PF13460,PF05368 AKAW2_60917S COG:K; EggNog:ENOG410PZMI; InterPro:IPR036864,IPR036236,IPR013087,IPR001138; PFAM:PF00172; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_60918A COG:S; EggNog:ENOG410PHAM; InterPro:IPR029057,IPR000836,IPR027417,IPR036412, IPR023214; PFAM:PF12710,PF14681,PF13207; go_process: GO:0009116 - nucleoside metabolic process [Evidence IEA] AKAW2_60919A COG:S; EggNog:ENOG410PPXM AKAW2_60920S CAZy:CE10; COG:I; EggNog:ENOG410PRC5; InterPro:IPR029058,IPR013094; MEROPS:MER0036044; PFAM:PF07859; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_60921S COG:F; EggNog:ENOG410PHZS; InterPro:IPR014485,IPR036907,IPR029052,IPR006179; SECRETED:SignalP(1-19); go_function: GO:0016787 - hydrolase activity [Evidence IEA]; go_process: GO:0009166 - nucleotide catabolic process [Evidence IEA] AKAW2_60922A COG:Q; EggNog:ENOG410PIX4; InterPro:IPR001128,IPR002401,IPR036396; PFAM:PF00067; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_60923A COG:S; EggNog:ENOG410PPIV; InterPro:IPR010730; PFAM:PF06985 AKAW2_60924S COG:S; EggNog:ENOG410PSJK AKAW2_60925A COG:P; EggNog:ENOG410PH3R; InterPro:IPR001734,IPR038377,IPR031155; PFAM:PF00474; TransMembrane:15 (o12-34i55-71o91-109i137-163o169-188i200-220o248-272i292- 318o354-380i401-423o429-451i458-477o497-518i597-617o629- 653i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0015204 - urea transmembrane transporter activity [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA]; go_process: GO:0071918 - urea transmembrane transport [Evidence IEA] AKAW2_60926A COG:E; EggNog:ENOG410PVJ9; InterPro:IPR002821,IPR008040,IPR003692; PFAM:PF01968,PF05378,PF02538; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_60928S COG:S; EggNog:ENOG410PYQ3; InterPro:IPR036864,IPR001138; PFAM:PF00172; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_60929A COG:T; EggNog:ENOG410PWKG; InterPro:IPR000719,IPR011009; PFAM:PF00069; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_60930A COG:G; EggNog:ENOG410QE3G; InterPro:IPR011701,IPR036259; PFAM:PF07690; TransMembrane:14 (i79-103o109-130i142-159o165-187i199-218o230-250i285- 304o316-334i354-379o391-411i423-441o447-466i487-507o563- 580i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_60931S COG:S; EggNog:ENOG410PR1M AKAW2_60932S COG:E; EggNog:ENOG410PUIZ; InterPro:IPR006076,IPR036188; PFAM:PF01266,PF13450; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_60933S COG:S; EggNog:ENOG410PWDA; InterPro:IPR036864,IPR001138; PFAM:PF00172; TransMembrane:1 (o497-515i); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_60934A COG:I; EggNog:ENOG410PVER; InterPro:IPR002018,IPR029058; MEROPS:MER0033226; PFAM:PF00135; SECRETED:SignalP(1-21) AKAW2_60936S COG:E; EggNog:ENOG410PJ18; InterPro:IPR013057; TransMembrane:5 (i49-70o76-98i128-152o158-176i188-207o) AKAW2_60937A COG:S; EggNog:ENOG410PP5P; InterPro:IPR036864,IPR001138; PFAM:PF00172; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_60938S COG:S; EggNog:ENOG410PSHR; TransMembrane:4 (i36-55o75-94i106-126o146-171i) AKAW2_60939A COG:I; EggNog:ENOG410PRI8; InterPro:IPR003140,IPR029058; PFAM:PF02230; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_60940S COG:S; EggNog:ENOG410PZGF AKAW2_60941A COG:S; EggNog:ENOG410PWF0; InterPro:IPR011009 AKAW2_60942S COG:S; EggNog:ENOG410PY96; InterPro:IPR023213 AKAW2_60943S COG:S; EggNog:ENOG410PY96; InterPro:IPR003480,IPR023213; go_function: GO:0016747 - transferase activity, transferring acyl groups other than amino-acyl groups [Evidence IEA] AKAW2_60944A COG:S; EggNog:ENOG410PNW4 AKAW2_60946A COG:S; EggNog:ENOG410PQP4; InterPro:IPR029063 AKAW2_60947S COG:I; EggNog:ENOG410PI45; InterPro:IPR001171,IPR018083; TransMembrane:2 (i33-51o63-85i); go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0016628 - oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor [Evidence IEA]; go_process: GO:0016126 - sterol biosynthetic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_60948S COG:Q; EggNog:ENOG410PHN2; InterPro:IPR043926,IPR027417,IPR003593,IPR017871, IPR003439,IPR013525; PFAM:PF01061,PF00005; TransMembrane:5 (o363-384i475-497o503-525i537-558o598-620i); go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA]; go_function: GO:0042626 - ATPase-coupled transmembrane transporter activity [Evidence IEA] AKAW2_60949S COG:Q; EggNog:ENOG410PHN2; InterPro:IPR043926,IPR027417,IPR003439,IPR013525; PFAM:PF01061,PF00005; TransMembrane:5 (o264-285i297-319o339-364i403-426o492-516i); go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0042626 - ATPase-coupled transmembrane transporter activity [Evidence IEA] AKAW2_60950A COG:S; EggNog:ENOG410Q053; SECRETED:SignalP(1-21) AKAW2_60951S COG:G; EggNog:ENOG410PKQP; InterPro:IPR035396,IPR008928,IPR035398,IPR012341; PFAM:PF17390,PF17389; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_60952S COG:G; EggNog:ENOG410PFDQ; InterPro:IPR011701,IPR036259; PFAM:PF07690; TransMembrane:9 (o6-25i32-49o55-74i95-113o133-152i248-267o273-295i307- 327o333-354i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_60953S COG:H; EggNog:ENOG410QDKJ; InterPro:IPR005814,IPR015424,IPR015421,IPR015422; PFAM:PF00202; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0008483 - transaminase activity [Evidence IEA]; go_function: GO:0030170 - pyridoxal phosphate binding [Evidence IEA] AKAW2_60954S COG:S; EggNog:ENOG410PMWA; TransMembrane:4 (i35-59o79-106i118-141o178-201i) AKAW2_60955A COG:S; EggNog:ENOG410Q1BH AKAW2_60957A COG:P; EggNog:ENOG410PHDT; InterPro:IPR020846,IPR005828,IPR036259; PFAM:PF00083; TransMembrane:11 (o136-159i171-188o194-212i254-271o283-302i342-363o383- 402i414-433o445-466i478-500o506-524i); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_60959S CAZy:AA1; COG:Q; EggNog:ENOG410PKIJ; InterPro:IPR008972,IPR011707,IPR011706,IPR001117; PFAM:PF00394,PF07732,PF07731; go_function: GO:0005507 - copper ion binding [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_60961A COG:G; EggNog:ENOG410PVXD; InterPro:IPR005829,IPR005828,IPR003663,IPR036259, IPR020846; PFAM:PF00083,PF07690; TransMembrane:12 (i50-76o96-117i124-144o150-171i183-202o214-235i315- 337o349-373i380-403o409-431i452-471o483-501i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_60962S COG:S; EggNog:ENOG410PHJN; InterPro:IPR036864,IPR001138; PFAM:PF00172; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_60963S COG:S; EggNog:ENOG410PNTG; InterPro:IPR019819,IPR019826,IPR002018,IPR029058; MEROPS:MER0034723; PFAM:PF00135; SECRETED:SignalP(1-22) AKAW2_60964S COG:S; EggNog:ENOG410PNTG; InterPro:IPR036691 AKAW2_60966A COG:I; EggNog:ENOG410PKCT; InterPro:IPR029154,IPR015815,IPR036291,IPR006115, IPR008927,IPR013328; PFAM:PF03446,PF14833; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0050661 - NADP binding [Evidence IEA]; go_function: GO:0051287 - NAD binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_60967A SECRETED:SignalP(1-19) AKAW2_60968A COG:S; EggNog:ENOG410PYWA AKAW2_60970S COG:S; EggNog:ENOG410PJF1 AKAW2_60971A CAZy:GH76; COG:G; EggNog:ENOG410PFRH; InterPro:IPR005198,IPR008928,IPR014480; PFAM:PF03663; SECRETED:SignalP(1-22); TransMembrane:1 (n10-18c22/23o423-446i); go_function: GO:0008496 - mannan endo-1,6-alpha-mannosidase activity [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA]; go_process: GO:0016052 - carbohydrate catabolic process [Evidence IEA] AKAW2_60972A COG:S; EggNog:ENOG410PXP7; SECRETED:SignalP(1-27) AKAW2_60973S COG:O; EggNog:ENOG410PHUB; InterPro:IPR042269,IPR008758,IPR029058; MEROPS:MER0093133; PFAM:PF05577; SECRETED:SignalP(1-17); go_function: GO:0008236 - serine-type peptidase activity [Evidence IEA]; go_process: GO:0006508 - proteolysis [Evidence IEA] AKAW2_60974A COG:T; EggNog:ENOG410PHPN; InterPro:IPR036188,IPR002938; PFAM:PF01494; go_function: GO:0071949 - FAD binding [Evidence IEA] AKAW2_60975S InterPro:IPR008427; PFAM:PF05730; TransMembrane:1 (o235-256i) AKAW2_60976A COG:S; EggNog:ENOG410PU0X; TransMembrane:3 (n10-20c25/26o49-69i81-100o106-126i) AKAW2_60977S COG:Q; EggNog:ENOG410PIQH; InterPro:IPR036188 AKAW2_60978S COG:Q; EggNog:ENOG410PIQH; InterPro:IPR002937,IPR036188; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_60979S InterPro:IPR021109 AKAW2_60981S InterPro:IPR021109 AKAW2_60982S COG:S; EggNog:ENOG410PXTD; TransMembrane:3 (i208-232o238-256i263-281o) AKAW2_60983A COG:K; EggNog:ENOG410Q2RR; InterPro:IPR036864,IPR001138; PFAM:PF00172; TransMembrane:1 (o569-588i); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_60984S COG:S; EggNog:ENOG410PIP3; InterPro:IPR011990; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_60985A SECRETED:SignalP(1-21) AKAW2_60986A COG:S; EggNog:ENOG410PJI7; InterPro:IPR021369; PFAM:PF11204; TransMembrane:4 (n5-17c22/23o200-221i241-258o322-342i354-374o) AKAW2_60987A COG:C; EggNog:ENOG410PW0R; InterPro:IPR014756,IPR036374,IPR005066,IPR008335, IPR000572; PFAM:PF00174,PF03404; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0030151 - molybdenum ion binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_60988S COG:T; EggNog:ENOG410PW6S; InterPro:IPR004839,IPR015424,IPR015421,IPR015422; PFAM:PF00155; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0030170 - pyridoxal phosphate binding [Evidence IEA]; go_process: GO:0009058 - biosynthetic process [Evidence IEA] AKAW2_60989A COG:U; EggNog:ENOG410QDYJ; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i75-94o114-132i144-162o168-191i203-225o237-263i311- 330o350-371i391-410o416-436i448-469o481-503i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_60990S COG:S; EggNog:ENOG410PJQR; InterPro:IPR017945,IPR006070; PFAM:PF01300; go_function: GO:0003725 - double-stranded RNA binding [Evidence IEA] AKAW2_60991A COG:S; EggNog:ENOG410PR0A; InterPro:IPR036864,IPR001138; PFAM:PF00172; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_60992A COG:S; EggNog:ENOG410Q1NX AKAW2_60993S CAZy:GH43; COG:G; EggNog:ENOG410PH4A; InterPro:IPR016840,IPR023296,IPR006710; PFAM:PF04616; SECRETED:SignalP(1-17); go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_function: GO:0046558 - arabinan endo-1,5-alpha-L-arabinosidase activity [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_60995A COG:S; EggNog:ENOG410Q2IB AKAW2_60996A COG:S; EggNog:ENOG410PYUG AKAW2_60998A COG:T; EggNog:ENOG410PFXV; InterPro:IPR019826,IPR002018,IPR029058; MEROPS:MER0033188; PFAM:PF00135; SECRETED:SignalP(1-20) AKAW2_60999A COG:K; EggNog:ENOG410PJIV; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172; TransMembrane:2 (o454-472i527-551o); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_61000A COG:Q; EggNog:ENOG410PVZQ; InterPro:IPR032710 AKAW2_61001A COG:C; EggNog:ENOG410PJ3B; InterPro:IPR001199,IPR037396,IPR008259,IPR013785, IPR036400,IPR000262,IPR018506; PFAM:PF00173,PF01070; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_61003S CAZy:AA4; COG:C; EggNog:ENOG410PKGU; InterPro:IPR016171,IPR006094,IPR036318,IPR004113, IPR016164,IPR016166,IPR016167,IPR016169; PFAM:PF02913,PF01565; TransMembrane:2 (o56-75i562-580o); go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_function: GO:0071949 - FAD binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_61004A COG:C; EggNog:ENOG410PMCP; InterPro:IPR013154,IPR013149,IPR036291,IPR011032, IPR020843; PFAM:PF00107,PF08240; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_61005S COG:S; EggNog:ENOG410PQUX; InterPro:IPR011008,IPR013097; PFAM:PF07876 AKAW2_61006A COG:M,P,T; EggNog:ENOG410PUCJ; InterPro:IPR002110,IPR027417,IPR007111,IPR036770, IPR020683; PFAM:PF05729,PF12796,PF00023,PF13637,PF13606; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_61007S COG:S; EggNog:ENOG410PZXQ AKAW2_61008S COG:S; EggNog:ENOG410PWV9 AKAW2_61009S COG:S; EggNog:ENOG410PSF9; InterPro:IPR011008,IPR009799; PFAM:PF07110; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA] AKAW2_61010A COG:G; EggNog:ENOG410PKNR; InterPro:IPR029226; PFAM:PF14856 AKAW2_61011S COG:S; EggNog:ENOG410PXBX; SECRETED:SignalP(1-23); TransMembrane:1 (n6-14c19/20o264-284i) AKAW2_61012A COG:S; EggNog:ENOG410PG0P; InterPro:IPR011118,IPR029058 AKAW2_61013A COG:Q; EggNog:ENOG410PWWV; InterPro:IPR015889; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016702 - oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_61014A COG:S; EggNog:ENOG410PVH4; InterPro:IPR029675; PFAM:PF04666; TransMembrane:3 (i21-38o258-276i288-307o); go_component: GO:0000139 - Golgi membrane [Evidence IEA]; go_function: GO:0016757 - transferase activity, transferring glycosyl groups [Evidence IEA]; go_process: GO:0006506 - GPI anchor biosynthetic process [Evidence IEA] AKAW2_61015S COG:S; EggNog:ENOG410PSM4; TransMembrane:4 (i40-62o82-105i112-129o158-182i) AKAW2_61016S COG:S; EggNog:ENOG410PSM4; TransMembrane:1 (o12-37i) AKAW2_61017S COG:S; EggNog:ENOG410PY2T; InterPro:IPR036864,IPR021858,IPR001138; PFAM:PF11951; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_61018S COG:S; EggNog:ENOG410PXBE; InterPro:IPR008253; PFAM:PF01284; TransMembrane:4 (i21-41o65-88i95-120o140-163i); go_component: GO:0016020 - membrane [Evidence IEA] AKAW2_61019A COG:S; EggNog:ENOG410PUH8; TransMembrane:7 (o12-32i44-63o97-118i130-153o173-197i209-233o253-277i) AKAW2_61020A COG:Q; EggNog:ENOG410PPCM; InterPro:IPR036291,IPR002347; PFAM:PF08659,PF00106,PF13561; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_61021A SECRETED:SignalP(1-19) AKAW2_61022S COG:S; EggNog:ENOG410PRA6; InterPro:IPR021765; PFAM:PF11807; go_process: GO:0043386 - mycotoxin biosynthetic process [Evidence IEA] AKAW2_61023A COG:S; EggNog:ENOG410PNMH; InterPro:IPR021765; PFAM:PF11807; TransMembrane:1 (i30-48o); go_process: GO:0043386 - mycotoxin biosynthetic process [Evidence IEA] AKAW2_61024S COG:S; EggNog:ENOG410PUIT; InterPro:IPR029063,IPR041698; PFAM:PF08241,PF13649 AKAW2_61025A COG:G; EggNog:ENOG410PW1G; InterPro:IPR036291,IPR020831,IPR020828,IPR020829; PFAM:PF02800; go_function: GO:0016620 - oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Evidence IEA]; go_function: GO:0051287 - NAD binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_61026A COG:G; EggNog:ENOG410PKV4; InterPro:IPR005829,IPR005828,IPR003663,IPR036259, IPR020846; PFAM:PF00083,PF07690; TransMembrane:12 (i12-31o71-91i100-121o127-146i158-180o192-211i277-300o320- 340i347-371o377-401i413-437o443-464i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_61027A COG:E; EggNog:ENOG410PK25; InterPro:IPR019818,IPR024084,IPR011829; PFAM:PF00180; go_function: GO:0000287 - magnesium ion binding [Evidence IEA]; go_function: GO:0016616 - oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Evidence IEA]; go_function: GO:0051287 - NAD binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_61028S COG:I; EggNog:ENOG410Q2DC; InterPro:IPR004695,IPR038665,IPR030185; PFAM:PF03595; TransMembrane:10 (i12-32o38-63i84-107o119-139i151-173o179-202i223-244o264- 290i302-321o333-357i); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0015140 - malate transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA]; go_process: GO:0071423 - malate transmembrane transport [Evidence IEA] AKAW2_61029A COG:S; EggNog:ENOG410PYEF; InterPro:IPR036864; TransMembrane:1 (i40-59o); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_61030S COG:K; EggNog:ENOG410PMF5; InterPro:IPR007219; PFAM:PF04082; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA] AKAW2_61031A BUSCO:EOG09261ONU; COG:G; EggNog:ENOG410PMD4; InterPro:IPR027417 AKAW2_61033S COG:Q; EggNog:ENOG410PHH6; InterPro:IPR001128,IPR002401,IPR036396; PFAM:PF00067; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_61034S COG:S; EggNog:ENOG410PVQT; InterPro:IPR011009,IPR002575; PFAM:PF01636 AKAW2_61035S COG:S; EggNog:ENOG410PVQT AKAW2_61037S COG:S; EggNog:ENOG410PUVU; InterPro:IPR011042; SECRETED:SignalP(1-26); antiSMASH:Cluster_6.2 AKAW2_61038A antiSMASH:Cluster_6.2 AKAW2_61039S COG:Q; EggNog:ENOG410PNVS; InterPro:IPR036291,IPR002347; PFAM:PF08659,PF00106,PF13561; SMCOG1001:short-chain dehydrogenase/reductase SDR; antiSMASH:Cluster_6.2; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_61040A COG:Q; EggNog:ENOG410PVPB; InterPro:IPR013149,IPR036291; PFAM:PF00107; SMCOG1040:alcohol dehydrogenase; antiSMASH:Cluster_6.2; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_61041A COG:I; EggNog:ENOG410PGS7; InterPro:IPR042099,IPR000873,IPR025110; PFAM:PF13193; SMCOG1002:AMP-dependent synthetase and ligase; antiSMASH:Cluster_6.2 AKAW2_61042A COG:Q; EggNog:ENOG410PIFN; InterPro:IPR004294; antiSMASH:Cluster_6.2; go_function: GO:0016702 - oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_61043A COG:Q; EggNog:ENOG410PIFN; InterPro:IPR004294; antiSMASH:Cluster_6.2; go_function: GO:0016702 - oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_61044S COG:I; EggNog:ENOG410PYG5; InterPro:IPR019845,IPR008949; PFAM:PF00494; antiSMASH:Cluster_6.2; go_function: GO:0016765 - transferase activity, transferring alkyl or aryl (other than methyl) groups [Evidence IEA] AKAW2_61045S COG:H; EggNog:ENOG410PG02; InterPro:IPR014105,IPR036188,IPR008150,IPR002937; PFAM:PF01593; SMCOG1222:dehydrogenase; TransMembrane:1 (i447-472o); antiSMASH:Cluster_6.2; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0016117 - carotenoid biosynthetic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_61046A COG:H; EggNog:ENOG410PG02; InterPro:IPR002937,IPR036188; PFAM:PF01593; SMCOG1222:dehydrogenase; TransMembrane:1 (o409-429i); antiSMASH:Cluster_6.2; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_61047S COG:I; EggNog:ENOG410PJ8T; InterPro:IPR000873,IPR036291,IPR013120,IPR042099; PFAM:PF00501,PF07993; SMCOG1002:AMP-dependent synthetase and ligase; antiSMASH:Cluster_6.2 AKAW2_61048S COG:Q; EggNog:ENOG410PK0J; InterPro:IPR006680,IPR011059,IPR032466; MEROPS:MER0005900; PFAM:PF01979; antiSMASH:Cluster_6.2; go_function: GO:0016787 - hydrolase activity [Evidence IEA]; go_function: GO:0016810 - hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [Evidence IEA] AKAW2_61049A COG:S; EggNog:ENOG410PQT1; InterPro:IPR000026,IPR016191; PFAM:PF00545; SECRETED:SignalP(1-20); antiSMASH:Cluster_6.2; go_function: GO:0003723 - RNA binding [Evidence IEA]; go_function: GO:0004521 - endoribonuclease activity [Evidence IEA]; go_function: GO:0004540 - ribonuclease activity [Evidence IEA] AKAW2_61050A COG:K; EggNog:ENOG410PFTN; InterPro:IPR008422,IPR001356,IPR013087,IPR009057; PFAM:PF05920; antiSMASH:Cluster_6.2; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_61051S COG:G; EggNog:ENOG410PMBP; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; SMCOG1005:Drug resistance transporter, EmrB/QacA; TransMembrane:14 (i68-93o105-123i135-154o166-187i194-218o224-243i263- 282o294-314i335-358o370-391i403-418o430-453i465-484o540- 558i); antiSMASH:Cluster_6.2; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_61052S antiSMASH:Cluster_6.2 AKAW2_61053A InterPro:IPR032675; antiSMASH:Cluster_6.2 AKAW2_61054S antiSMASH:Cluster_6.2 AKAW2_61055A COG:O; EggNog:ENOG410PM9H; InterPro:IPR023753,IPR036188; PFAM:PF07992; SMCOG1176:alkyl hydroperoxide reductase subunit; antiSMASH:Cluster_6.2; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_61056A COG:S; EggNog:ENOG410PT3K; antiSMASH:Cluster_6.2 AKAW2_61057S COG:S; EggNog:ENOG410Q2D6 AKAW2_61058A COG:S; EggNog:ENOG410PWPY AKAW2_61059A COG:S; EggNog:ENOG410PWPY; InterPro:IPR029063,IPR008854; PFAM:PF05724; go_function: GO:0008757 - S-adenosylmethionine-dependent methyltransferase activity [Evidence IEA] AKAW2_61060S COG:U; EggNog:ENOG410QE2A; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:14 (i53-79o91-112i119-139o145-166i178-197o209-229i250- 270o282-299i320-339o359-381i388-410o416-442i449-473o498- 518i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_61061A COG:Q; EggNog:ENOG410PW83; InterPro:IPR036188,IPR000960; PFAM:PF13738,PF13454,PF13450,PF07992; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_function: GO:0050661 - NADP binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_61062S COG:Q; EggNog:ENOG410PK6E; InterPro:IPR013154,IPR013149,IPR002328,IPR036291, IPR011032,IPR020843; PFAM:PF00107,PF08240; SMCOG1040:alcohol dehydrogenase; antiSMASH:Cluster_6.4; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_61063A COG:S; EggNog:ENOG410PJZM; InterPro:IPR011701,IPR036259; PFAM:PF07690,PF05978; TransMembrane:11 (i12-31o51-74i81-100o106-134i141-165o177-198i226-248o268- 288i300-323o343-364i404-425o); antiSMASH:Cluster_6.4; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_61064A COG:S; EggNog:ENOG410PI2E; antiSMASH:Cluster_6.4 AKAW2_61065A CAZy:GT32; COG:M; EggNog:ENOG410PVFZ; InterPro:IPR029044,IPR007577,IPR039367; PFAM:PF04488; TransMembrane:1 (o45-66i); antiSMASH:Cluster_6.4; go_function: GO:0000009 - alpha-1,6-mannosyltransferase activity [Evidence IEA] AKAW2_61066S COG:S; EggNog:ENOG410PTJI; SECRETED:SignalP(1-30); TransMembrane:1 (n12-25c30/31o196-220i); antiSMASH:Cluster_6.4 AKAW2_61067A COG:S; EggNog:ENOG410PII3; InterPro:IPR005645,IPR029058; PFAM:PF03959; antiSMASH:Cluster_6.4 AKAW2_61068A COG:S; EggNog:ENOG410PII3; InterPro:IPR005645,IPR029058; PFAM:PF03959; antiSMASH:Cluster_6.4 AKAW2_61069S COG:Q; EggNog:ENOG410PM5V; InterPro:IPR016036,IPR016035,IPR016039,IPR018201, IPR042104,IPR014030,IPR011032,IPR013968,IPR013154, IPR001227,IPR032821,IPR014031,IPR006162,IPR014043, IPR020806,IPR020807,IPR020843,IPR020841,IPR009081, IPR013149,IPR036736,IPR036291; PFAM:PF16197,PF08659,PF00550,PF02801,PF00698, PF13602,PF14765,PF00107,PF00106,PF00109,PF08240; SMCOG1022:Beta-ketoacyl synthase; antiSMASH:Cluster_6.4; go_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein] synthase activity [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0016740 - transferase activity [Evidence IEA]; go_function: GO:0016746 - transferase activity, transferring acyl groups [Evidence IEA]; go_function: GO:0031177 - phosphopantetheine binding [Evidence IEA]; go_process: GO:0006633 - fatty acid biosynthetic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_61070A CAZy:AA7; COG:C; EggNog:ENOG410PM8F; InterPro:IPR006093,IPR006094,IPR036318,IPR016169, IPR016166,IPR016167,IPR012951; PFAM:PF08031,PF01565; SMCOG1138:FAD linked oxidase domain protein; antiSMASH:Cluster_6.4; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_function: GO:0071949 - FAD binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_61071A COG:S; EggNog:ENOG410Q2S8; InterPro:IPR040602; PFAM:PF18631; antiSMASH:Cluster_6.4 AKAW2_61072S COG:S; EggNog:ENOG410Q1WF; InterPro:IPR029032; SMCOG1298:putative carboxymuconolactone decarboxylase; antiSMASH:Cluster_6.4 AKAW2_61073S COG:E; EggNog:ENOG410PVBD; InterPro:IPR019996,IPR005801,IPR015890; PFAM:PF00425; SMCOG1018:isochorismate synthase; antiSMASH:Cluster_6.4; go_function: GO:0008909 - isochorismate synthase activity [Evidence IEA]; go_function: GO:0016833 - oxo-acid-lyase activity [Evidence IEA]; go_process: GO:0009058 - biosynthetic process [Evidence IEA] AKAW2_61074S COG:Q; EggNog:ENOG410PWPR; InterPro:IPR001128,IPR036396; PFAM:PF00067; SMCOG1034:cytochrome P450; TransMembrane:1 (o6-26i); antiSMASH:Cluster_6.4; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_61075A COG:U; EggNog:ENOG410PUAF; InterPro:IPR036291,IPR008030; PFAM:PF13460,PF05368,PF03435; antiSMASH:Cluster_6.4 AKAW2_61076A COG:S; EggNog:ENOG410PVG5; InterPro:IPR036864,IPR040331,IPR007219,IPR001138; PFAM:PF00172,PF04082; antiSMASH:Cluster_6.4; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0003700 - DNA-binding transcription factor activity [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_61077S COG:S; EggNog:ENOG410PK66; TransMembrane:1 (o52-71i); antiSMASH:Cluster_6.4 AKAW2_61078A COG:P; EggNog:ENOG410PHHN; InterPro:IPR001734,IPR038377,IPR031155; PFAM:PF00474; TransMembrane:15 (o12-33i54-71o91-110i130-153o165-184i191-210o253-275i287- 312o352-375i396-418o430-448i455-474o494-515i588-607o619- 644i); antiSMASH:Cluster_6.4; go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0015204 - urea transmembrane transporter activity [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA]; go_process: GO:0071918 - urea transmembrane transport [Evidence IEA] AKAW2_61079A COG:S; EggNog:ENOG410PQ5B; InterPro:IPR000073,IPR029058; PFAM:PF12697; antiSMASH:Cluster_6.5 AKAW2_61080A COG:K; EggNog:ENOG410Q1WU; InterPro:IPR001138,IPR007219,IPR036864; antiSMASH:Cluster_6.5; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_61081S antiSMASH:Cluster_6.5 AKAW2_61082S COG:O; EggNog:ENOG410PI0U; InterPro:IPR036188; PFAM:PF01266,PF13450; SECRETED:SignalP(1-22); antiSMASH:Cluster_6.5 AKAW2_61083A antiSMASH:Cluster_6.5 AKAW2_61084S COG:I; EggNog:ENOG410PJB7; InterPro:IPR000873,IPR001242,IPR009081,IPR006162, IPR029063,IPR036736,IPR029058,IPR001031,IPR020845, IPR020806,IPR023213,IPR042099,IPR010071,IPR025110; PFAM:PF00501,PF00668,PF13193,PF00550,PF00975; SMCOG1209:polyketide synthase associated protein papA3; antiSMASH:Cluster_6.5; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0016788 - hydrolase activity, acting on ester bonds [Evidence IEA]; go_function: GO:0031177 - phosphopantetheine binding [Evidence IEA]; go_process: GO:0009058 - biosynthetic process [Evidence IEA] AKAW2_61085S COG:S; EggNog:ENOG410PW90; InterPro:IPR040632,IPR027417; PFAM:PF17784; TransMembrane:1 (o240-260i); antiSMASH:Cluster_6.5 AKAW2_61086A COG:I; EggNog:ENOG410PW3B; InterPro:IPR029058,IPR001031; antiSMASH:Cluster_6.5; go_function: GO:0016788 - hydrolase activity, acting on ester bonds [Evidence IEA]; go_process: GO:0009058 - biosynthetic process [Evidence IEA] AKAW2_61087A COG:Q; EggNog:ENOG410PHKY; InterPro:IPR011059,IPR006680,IPR032466; TransMembrane:1 (i33-51o); antiSMASH:Cluster_6.5; go_function: GO:0016787 - hydrolase activity [Evidence IEA]; go_function: GO:0016810 - hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [Evidence IEA] AKAW2_61088S COG:S; EggNog:ENOG410PSKI; InterPro:IPR000073,IPR029058; PFAM:PF12697; antiSMASH:Cluster_6.5 AKAW2_61089S COG:S; EggNog:ENOG410PYZ0; InterPro:IPR001810,IPR036047; PFAM:PF00646; antiSMASH:Cluster_6.5; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_61090A CAZy:AA3; COG:E; EggNog:ENOG410PM8U; InterPro:IPR012132,IPR036188,IPR000172,IPR007867; PFAM:PF05199,PF00732; antiSMASH:Cluster_6.5; go_function: GO:0016614 - oxidoreductase activity, acting on CH-OH group of donors [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_61091S COG:E; EggNog:ENOG410PHWR; InterPro:IPR002872,IPR015659,IPR029041; PFAM:PF01619; antiSMASH:Cluster_6.5; go_function: GO:0004657 - proline dehydrogenase activity [Evidence IEA]; go_process: GO:0006562 - proline catabolic process [Evidence IEA] AKAW2_61092S COG:S; EggNog:ENOG410PUGV; InterPro:IPR007219; TransMembrane:1 (o326-344i); antiSMASH:Cluster_6.5; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA] AKAW2_61093A COG:E; EggNog:ENOG410PG3T; InterPro:IPR015590,IPR005931,IPR029510,IPR016160, IPR016161,IPR016162,IPR016163; PFAM:PF00171; antiSMASH:Cluster_6.5; go_function: GO:0003842 - 1-pyrroline-5-carboxylate dehydrogenase activity [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0016620 - oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Evidence IEA]; go_process: GO:0010133 - proline catabolic process to glutamate [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_61094S COG:C; EggNog:ENOG410PG0F; InterPro:IPR018108,IPR023395; PFAM:PF00153 AKAW2_61095S COG:J; EggNog:ENOG410PGDA AKAW2_61096S COG:J; EggNog:ENOG410PGDA; InterPro:IPR036621,IPR017449,IPR004154,IPR016061; PFAM:PF03129,PF09180; go_component: GO:0005737 - cytoplasm [Evidence IEA]; go_function: GO:0000166 - nucleotide binding [Evidence IEA]; go_function: GO:0004827 - proline-tRNA ligase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006433 - prolyl-tRNA aminoacylation [Evidence IEA] AKAW2_61098S COG:E; EggNog:ENOG410PJ18; InterPro:IPR013057; PFAM:PF01490; TransMembrane:11 (i12-35o41-62i90-113o119-138i150-171o202-220i232-254o274- 293i314-335o347-367i387-411o) AKAW2_61099A COG:S; EggNog:ENOG410Q1ED AKAW2_61100S COG:S; EggNog:ENOG410PPKK; InterPro:IPR036291 AKAW2_61101A COG:S; EggNog:ENOG410PXBR; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; TransMembrane:1 (o619-640i); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_61102A COG:S; EggNog:ENOG410Q1XV AKAW2_61103A COG:S; EggNog:ENOG410PXHG; InterPro:IPR036861,IPR001002; PFAM:PF00187; go_function: GO:0008061 - chitin binding [Evidence IEA] AKAW2_61104S InterPro:IPR018466; PFAM:PF10342; SECRETED:SignalP(1-23) AKAW2_61105A COG:O; EggNog:ENOG410PQYQ; InterPro:IPR039732,IPR029071; go_process: GO:0006464 - cellular protein modification process [Evidence IEA] AKAW2_61106A COG:S; EggNog:ENOG410PRGJ; InterPro:IPR036236,IPR036864,IPR013087,IPR001138; PFAM:PF00172,PF00096; TransMembrane:1 (o547-566i); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_61107A COG:Q; EggNog:ENOG410PI4T; InterPro:IPR020946,IPR036188; PFAM:PF07992,PF13434,PF13450; go_function: GO:0004499 - N,N-dimethylaniline monooxygenase activity [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_function: GO:0050661 - NADP binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_61108S COG:C,H; EggNog:ENOG410PG2K; InterPro:IPR036188,IPR002938,IPR036249,IPR038220, IPR012941; PFAM:PF07976,PF01494; go_function: GO:0071949 - FAD binding [Evidence IEA] AKAW2_61109S COG:G; EggNog:ENOG410PFE6; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i152-177o189-209i221-240o246-268i280-301o307-329i385- 404o424-446i467-488o494-515i527-548o560-581i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_61110A COG:S; EggNog:ENOG410Q26A AKAW2_61111A COG:Q; EggNog:ENOG410PIXU; InterPro:IPR015889,IPR000627; PFAM:PF00775; SECRETED:SignalP(1-20); go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0008199 - ferric iron binding [Evidence IEA]; go_function: GO:0016702 - oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [Evidence IEA]; go_process: GO:0006725 - cellular aromatic compound metabolic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_61112A COG:A; EggNog:ENOG410PFSV; InterPro:IPR005829,IPR005828,IPR003663,IPR036259, IPR020846; PFAM:PF00083,PF07690; TransMembrane:12 (i20-40o75-95i102-120o126-148i160-182o194-213i303-321o327- 348i355-377o389-411i423-446o458-476i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_61113A COG:S; EggNog:ENOG410PTDJ; InterPro:IPR011058,IPR036673; PFAM:PF08881 AKAW2_61114A COG:Q; EggNog:ENOG410PNIC; InterPro:IPR036291,IPR002347,IPR020904; PFAM:PF00106,PF13561; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_61115A CAZy:GH28; COG:G; EggNog:ENOG410PG7M; InterPro:IPR000743,IPR012334,IPR011050; PFAM:PF00295; SECRETED:SignalP(1-22); go_function: GO:0004650 - polygalacturonase activity [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_61116A BUSCO:EOG09265BTC; COG:S; EggNog:ENOG410PQ3P; InterPro:IPR005336; PFAM:PF03650; TransMembrane:1 (i115-136o); go_component: GO:0005743 - mitochondrial inner membrane [Evidence IEA]; go_process: GO:0006850 - mitochondrial pyruvate transmembrane transport [Evidence IEA] AKAW2_61117S COG:C; EggNog:ENOG410PRQR; InterPro:IPR016464,IPR036249,IPR007741; PFAM:PF05047 AKAW2_61118A COG:S; EggNog:ENOG410PMBR; InterPro:IPR014436,IPR004183; PFAM:PF02900; TransMembrane:1 (i31-51o); go_function: GO:0008198 - ferrous iron binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0016701 - oxidoreductase activity, acting on single donors with incorporation of molecular oxygen [Evidence IEA]; go_process: GO:0006725 - cellular aromatic compound metabolic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_61119A COG:M,O,T; EggNog:ENOG410PHQ7; InterPro:IPR011990,IPR006597; PFAM:PF08238; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_61120S COG:U; EggNog:ENOG410PS0U; InterPro:IPR012420; PFAM:PF07960; TransMembrane:1 (o6-28i) AKAW2_61121S COG:U; EggNog:ENOG410PR0D; InterPro:IPR042855,IPR016444,IPR001388; PFAM:PF00957; TransMembrane:1 (i94-115o); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_process: GO:0016192 - vesicle-mediated transport [Evidence IEA] AKAW2_61122S COG:E; EggNog:ENOG410PFGY; InterPro:IPR001048,IPR041734,IPR023013,IPR004662, IPR000534,IPR036393,IPR000706,IPR011241,IPR036291, IPR006855; PFAM:PF01118,PF04768,PF00696; go_component: GO:0005737 - cytoplasm [Evidence IEA]; go_component: GO:0005739 - mitochondrion [Evidence IEA]; go_function: GO:0003942 - N-acetyl-gamma-glutamyl-phosphate reductase activity [Evidence IEA]; go_function: GO:0003991 - acetylglutamate kinase activity [Evidence IEA]; go_function: GO:0016620 - oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Evidence IEA]; go_function: GO:0051287 - NAD binding [Evidence IEA]; go_process: GO:0006526 - arginine biosynthetic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_61123S BUSCO:EOG0926115V; COG:D; EggNog:ENOG410PKB2; InterPro:IPR039781,IPR006910; PFAM:PF04825; go_component: GO:0008278 - cohesin complex [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0007062 - sister chromatid cohesion [Evidence IEA] AKAW2_61124S COG:S; EggNog:ENOG410PQSE; InterPro:IPR020915; PFAM:PF11578 AKAW2_61125A COG:S; EggNog:ENOG410PWV9; InterPro:IPR001810; PFAM:PF12937; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_61126A COG:C; EggNog:ENOG410PGND; InterPro:IPR039556,IPR006254,IPR040442,IPR015813, IPR018523; PFAM:PF00463,PF13714; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0004451 - isocitrate lyase activity [Evidence IEA]; go_process: GO:0019752 - carboxylic acid metabolic process [Evidence IEA] AKAW2_61128S COG:E; EggNog:ENOG410PKVY; InterPro:IPR029055,IPR006426,IPR017932,IPR033738, IPR001962; MEROPS:MER0034539; PFAM:PF13522,PF00733,PF13537; go_function: GO:0004066 - asparagine synthase (glutamine-hydrolyzing) activity [Evidence IEA]; go_process: GO:0006529 - asparagine biosynthetic process [Evidence IEA] AKAW2_61129A COG:S; EggNog:ENOG410PNN3; InterPro:IPR011330,IPR005501; PFAM:PF03746; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_61130S COG:S; EggNog:ENOG410PGT5; InterPro:IPR036864,IPR021858,IPR001138; PFAM:PF00172,PF11951; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_61132S COG:S; EggNog:ENOG410PP8H; InterPro:IPR014710,IPR010424,IPR011051; PFAM:PF05899 AKAW2_61133S BUSCO:EOG09261AMX; COG:T; EggNog:ENOG410PI9E; InterPro:IPR017441,IPR017892,IPR008271,IPR000961, IPR000719,IPR011009; PFAM:PF00433,PF07714,PF00069; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0004674 - protein serine/threonine kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_61134A COG:S; EggNog:ENOG410PQGS; InterPro:IPR012882,IPR036249; PFAM:PF07955; go_component: GO:0005739 - mitochondrion [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_61135A COG:P,Q; EggNog:ENOG410PHKD; InterPro:IPR017938,IPR017927,IPR013130,IPR013121, IPR039261,IPR013112; PFAM:PF08022,PF01794,PF08030; TransMembrane:7 (o26-44i98-122o134-154i175-193o213-232i239-259o265-284i); go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_61136S COG:P; EggNog:ENOG410PQ4J; InterPro:IPR007274; PFAM:PF04145; TransMembrane:2 (n85-97c102/103o174-194i201-220o); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0005375 - copper ion transmembrane transporter activity [Evidence IEA]; go_process: GO:0035434 - copper ion transmembrane transport [Evidence IEA] AKAW2_61137A COG:G,Q; EggNog:ENOG410PPEY; InterPro:IPR036291,IPR000683; PFAM:PF01408; TransMembrane:1 (i93-114o); go_function: GO:0016491 - oxidoreductase activity [Evidence IEA] AKAW2_61138S COG:O; EggNog:ENOG410PWXE; SECRETED:SignalP(1-17) AKAW2_61139S COG:I; EggNog:ENOG410PPHI; InterPro:IPR003140,IPR029058; MEROPS:MER0200434; PFAM:PF02230,PF03959; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_61140A COG:S; EggNog:ENOG410PYGQ; InterPro:IPR005645,IPR029058; PFAM:PF03959 AKAW2_61141S COG:Q; EggNog:ENOG410PVR8; InterPro:IPR036291,IPR002347; PFAM:PF08659,PF00106,PF13561; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_61142S BUSCO:EOG092653SU; COG:K; EggNog:ENOG410PPVK; InterPro:IPR039370,IPR038187,IPR002715; PFAM:PF01849 AKAW2_61143A COG:S; EggNog:ENOG410PIXA; InterPro:IPR001841,IPR036322,IPR006575,IPR001680, IPR017986; PFAM:PF17120,PF00400; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_61144S COG:O; EggNog:ENOG410PN27; InterPro:IPR016135,IPR023313,IPR000608; PFAM:PF00179 AKAW2_61145S COG:S; EggNog:ENOG410Q2RG AKAW2_61146S COG:J; EggNog:ENOG410PNQT; InterPro:IPR038630,IPR000988,IPR023442; PFAM:PF01246 AKAW2_61147A COG:M; EggNog:ENOG410PNHJ; InterPro:IPR039143,IPR000182,IPR016181; PFAM:PF13673,PF00583; go_function: GO:0004343 - glucosamine 6-phosphate N-acetyltransferase activity [Evidence IEA]; go_function: GO:0008080 - N-acetyltransferase activity [Evidence IEA]; go_process: GO:0006048 - UDP-N-acetylglucosamine biosynthetic process [Evidence IEA] AKAW2_61148A COG:C; EggNog:ENOG410PIAD; InterPro:IPR005677,IPR022761,IPR018951,IPR024083, IPR020557,IPR008948,IPR000362; PFAM:PF00206,PF10415; go_component: GO:0045239 - tricarboxylic acid cycle enzyme complex [Evidence IEA]; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0004333 - fumarate hydratase activity [Evidence IEA]; go_function: GO:0016829 - lyase activity [Evidence IEA]; go_process: GO:0006099 - tricarboxylic acid cycle [Evidence IEA]; go_process: GO:0006106 - fumarate metabolic process [Evidence IEA] AKAW2_61149A CAZy:CE10; COG:V; EggNog:ENOG410PKVE; InterPro:IPR029058,IPR013094; MEROPS:MER0034665; PFAM:PF07859; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_61150S COG:E; EggNog:ENOG410PMJZ; InterPro:IPR004839,IPR004838,IPR000796,IPR015424, IPR015421,IPR015422; PFAM:PF00155; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0008483 - transaminase activity [Evidence IEA]; go_function: GO:0030170 - pyridoxal phosphate binding [Evidence IEA]; go_process: GO:0006520 - cellular amino acid metabolic process [Evidence IEA]; go_process: GO:0009058 - biosynthetic process [Evidence IEA] AKAW2_61151A BUSCO:EOG092612CC; COG:L; EggNog:ENOG410PGHB; InterPro:IPR031669,IPR036420,IPR003961,IPR001357, IPR031673,IPR013783,IPR036116; PFAM:PF12738,PF00533,PF16892,PF16893; go_function: GO:0005515 - protein binding [Evidence IEA]; go_function: GO:0046983 - protein dimerization activity [Evidence IEA] AKAW2_61152A COG:S; EggNog:ENOG410PYXB AKAW2_61153S BUSCO:EOG092652Y6; COG:J; EggNog:ENOG410PN1R; InterPro:IPR001253,IPR006196,IPR018104,IPR012340; PFAM:PF01176; go_function: GO:0003723 - RNA binding [Evidence IEA]; go_function: GO:0003743 - translation initiation factor activity [Evidence IEA]; go_process: GO:0006413 - translational initiation [Evidence IEA] AKAW2_61154A BUSCO:EOG09260AZK; COG:L; EggNog:ENOG410PG6F; InterPro:IPR011335,IPR006167,IPR006166,IPR010994; PFAM:PF02732; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0003697 - single-stranded DNA binding [Evidence IEA]; go_function: GO:0004518 - nuclease activity [Evidence IEA]; go_function: GO:0004520 - endodeoxyribonuclease activity [Evidence IEA]; go_process: GO:0006281 - DNA repair [Evidence IEA] AKAW2_61155A COG:S; EggNog:ENOG410Q2KC AKAW2_61156S BUSCO:EOG09264U78; COG:T,Z; EggNog:ENOG410PJI4; InterPro:IPR000697,IPR003124,IPR011993,IPR027641, IPR033927; PFAM:PF00568; go_function: GO:0003779 - actin binding [Evidence IEA]; go_process: GO:0007015 - actin filament organization [Evidence IEA]; go_process: GO:2000601 - positive regulation of Arp2/3 complex-mediated actin nucleation [Evidence IEA] AKAW2_61157S COG:P; EggNog:ENOG410PFS4; InterPro:IPR039204; TransMembrane:2 (i430-448o460-482i) AKAW2_61158A BUSCO:EOG092614DJ; COG:S; EggNog:ENOG410PIV3; InterPro:IPR011671; PFAM:PF07757; go_function: GO:0008168 - methyltransferase activity [Evidence IEA] AKAW2_61159S COG:S; EggNog:ENOG410PJ3K; InterPro:IPR013752,IPR013332,IPR008927,IPR013328; PFAM:PF02558,PF08546; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_61160S COG:S; EggNog:ENOG410PSIN; InterPro:IPR042332,IPR013183; PFAM:PF08227; go_process: GO:0008608 - attachment of spindle microtubules to kinetochore [Evidence IEA] AKAW2_61161A COG:G; EggNog:ENOG410QEDC; InterPro:IPR013078,IPR029033; PFAM:PF00300 AKAW2_61162A BUSCO:EOG09262E4Q; COG:A; EggNog:ENOG410PGTN; InterPro:IPR027417,IPR001650,IPR014014,IPR014001, IPR011545; PFAM:PF04851,PF00270,PF00271; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0004386 - helicase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA] AKAW2_61163S COG:A; EggNog:ENOG410PSI0; InterPro:IPR007175; PFAM:PF04032 AKAW2_61164A COG:S; EggNog:ENOG410PSSC; InterPro:IPR034455; go_component: GO:0031083 - BLOC-1 complex [Evidence IEA] AKAW2_61165S COG:S; EggNog:ENOG410PIJW; InterPro:IPR019007; PFAM:PF09429; go_process: GO:0006396 - RNA processing [Evidence IEA] AKAW2_61166A BUSCO:EOG092626EQ; COG:T; EggNog:ENOG410PIY3; InterPro:IPR000719,IPR011009,IPR008271; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_61167S COG:S; EggNog:ENOG410PGYX; InterPro:IPR036770,IPR002110,IPR000210,IPR011333, IPR020683; PFAM:PF12796,PF00023,PF00651,PF13637,PF13857; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_61168A TransMembrane:1 (o14-35i) AKAW2_61169A TransMembrane:1 (i91-111o) AKAW2_61170S COG:K; EggNog:ENOG410PS2T; InterPro:IPR036236,IPR013087; PFAM:PF00096 AKAW2_61171A BUSCO:EOG0926071Q; COG:B,D,L; EggNog:ENOG410PGSX; InterPro:IPR003395,IPR027417,IPR027131; PFAM:PF13476,PF02463; go_component: GO:0030915 - Smc5-Smc6 complex [Evidence IEA]; go_process: GO:0000724 - double-strand break repair via homologous recombination [Evidence IEA]; go_process: GO:0006281 - DNA repair [Evidence IEA]; go_process: GO:0007062 - sister chromatid cohesion [Evidence IEA] AKAW2_61172S COG:S; EggNog:ENOG410PTQG AKAW2_61173A COG:I; EggNog:ENOG410PFJM; InterPro:IPR002921,IPR029058; PFAM:PF01764; go_process: GO:0006629 - lipid metabolic process [Evidence IEA] AKAW2_61174A COG:C; EggNog:ENOG410PG98; InterPro:IPR037396,IPR000262,IPR013785; PFAM:PF01070; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA] AKAW2_61175A CAZy:GH32; COG:G; EggNog:ENOG410PUNW; InterPro:IPR023296,IPR013148,IPR013189,IPR018053, IPR013320,IPR001362; PFAM:PF00251,PF08244; TransMembrane:1 (o20-41i); go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_61176S COG:S; EggNog:ENOG410PWGZ; InterPro:IPR011009,IPR002575; PFAM:PF01636 AKAW2_61177A COG:S; EggNog:ENOG410Q576 AKAW2_61178S COG:G; EggNog:ENOG410PFT2; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i46-66o86-105i117-134o140-165i177-197o209-231i280- 298o318-338i345-364o370-393i405-425o437-458i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_61179S COG:S; EggNog:ENOG410PI0W; InterPro:IPR000560,IPR029033; PFAM:PF00328 AKAW2_61180S COG:S; EggNog:ENOG410PI0W; InterPro:IPR012677 AKAW2_61181A COG:G; EggNog:ENOG410PKEX; InterPro:IPR020846,IPR036259,IPR010573; PFAM:PF06609,PF07690; TransMembrane:12 (i54-71o91-113i120-138o144-167i179-202o208-229i250- 269o281-298i318-340o360-380i387-405o411-438i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_61182A COG:S; EggNog:ENOG410PQQJ; InterPro:IPR029069,IPR006683; PFAM:PF03061; TransMembrane:1 (i51-68o) AKAW2_61183A BUSCO:EOG09263BGW; COG:O; EggNog:ENOG410PITP; InterPro:IPR038765,IPR029071,IPR001394,IPR018200, IPR000626,IPR028889; MEROPS:MER0004316; PFAM:PF13423,PF00240,PF00443; go_function: GO:0004843 - thiol-dependent ubiquitin-specific protease activity [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0006511 - ubiquitin-dependent protein catabolic process [Evidence IEA]; go_process: GO:0016579 - protein deubiquitination [Evidence IEA] AKAW2_61184S BUSCO:EOG09265CCT; COG:Z; EggNog:ENOG410PFJR; InterPro:IPR034666,IPR008384; PFAM:PF05856; go_component: GO:0005885 - Arp2/3 protein complex [Evidence IEA]; go_component: GO:0015629 - actin cytoskeleton [Evidence IEA]; go_process: GO:0030041 - actin filament polymerization [Evidence IEA]; go_process: GO:0030833 - regulation of actin filament polymerization [Evidence IEA]; go_process: GO:0034314 - Arp2/3 complex-mediated actin nucleation [Evidence IEA] AKAW2_61185S COG:S; EggNog:ENOG410PQ10 AKAW2_61186S COG:S; EggNog:ENOG410PQ10 AKAW2_61187A COG:S; EggNog:ENOG410PKAE; InterPro:IPR003827,IPR036602; PFAM:PF02676 AKAW2_61191S COG:S; EggNog:ENOG410PV5U; InterPro:IPR036864,IPR001138; PFAM:PF00172; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_61192A COG:D; EggNog:ENOG410PFHB; InterPro:IPR017441,IPR008271,IPR043024,IPR031850, IPR000719,IPR011009; PFAM:PF00069,PF07714,PF16797; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_61193A COG:S; EggNog:ENOG410PNXY; InterPro:IPR009783,IPR032710; PFAM:PF07080 AKAW2_61194S COG:S; EggNog:ENOG410PJV4; InterPro:IPR000073,IPR029058,IPR013595; MEROPS:MER0004231; PFAM:PF08386,PF00561; TransMembrane:2 (o28-47i310-328o) AKAW2_61195S COG:O; EggNog:ENOG410PP0P; InterPro:IPR013740,IPR036249,IPR037944,IPR013766; PFAM:PF08534,PF00578; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA] AKAW2_61196S BUSCO:EOG09260TPT; COG:A; EggNog:ENOG410PHWG; InterPro:IPR039182,IPR012590,IPR009723; PFAM:PF08170,PF06978; go_component: GO:0000172 - ribonuclease MRP complex [Evidence IEA]; go_component: GO:0005655 - nucleolar ribonuclease P complex [Evidence IEA]; go_process: GO:0001682 - tRNA 5'-leader removal [Evidence IEA] AKAW2_61197A BUSCO:EOG09264OBO; COG:S; EggNog:ENOG410PQWT; InterPro:IPR012471 AKAW2_61198S COG:G; EggNog:ENOG410PIUH; InterPro:IPR001312,IPR019807,IPR022673,IPR022672, IPR043129; PFAM:PF00349,PF03727; go_function: GO:0004396 - hexokinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0005536 - glucose binding [Evidence IEA]; go_function: GO:0016773 - phosphotransferase activity, alcohol group as acceptor [Evidence IEA]; go_process: GO:0001678 - cellular glucose homeostasis [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA]; go_process: GO:0006096 - glycolytic process [Evidence IEA] AKAW2_61199S COG:G; EggNog:ENOG410QE2U; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:14 (i80-106o118-140i147-167o173-193i205-224o236-256i277- 296o308-325i345-366o386-405i412-430o436-454i475-496o545- 564i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_61200A COG:S; EggNog:ENOG410PXV0; InterPro:IPR007248; PFAM:PF04117; TransMembrane:3 (n5-15c23/24o43-61i145-171o215-234i); go_component: GO:0016021 - integral component of membrane [Evidence IEA] AKAW2_61201A COG:Q; EggNog:ENOG410PHJE; InterPro:IPR001128,IPR017972,IPR002401,IPR036396; PFAM:PF00067; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_61202A COG:K; EggNog:ENOG410PHB9; InterPro:IPR009349,IPR039128; PFAM:PF06221; go_component: GO:0005634 - nucleus [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_61203A COG:K; EggNog:ENOG410PJI8; InterPro:IPR013246; PFAM:PF08209 AKAW2_61204S COG:S; EggNog:ENOG410PPX5; InterPro:IPR016181 AKAW2_61205S COG:J; EggNog:ENOG410PKH7; InterPro:IPR033196,IPR020568,IPR027408,IPR001247, IPR036345; PFAM:PF01138; go_component: GO:0000178 - exosome (RNase complex) [Evidence IEA]; go_process: GO:0006396 - RNA processing [Evidence IEA]; go_process: GO:0006401 - RNA catabolic process [Evidence IEA] AKAW2_61206S COG:O; EggNog:ENOG410PMZB; InterPro:IPR024936,IPR029000,IPR020892,IPR002130; PFAM:PF00160; go_function: GO:0003755 - peptidyl-prolyl cis-trans isomerase activity [Evidence IEA]; go_process: GO:0000413 - protein peptidyl-prolyl isomerization [Evidence IEA]; go_process: GO:0006457 - protein folding [Evidence IEA] AKAW2_61207S COG:O; EggNog:ENOG410PGJ6; InterPro:IPR018203,IPR017230,IPR036188; PFAM:PF00996; go_function: GO:0005092 - GDP-dissociation inhibitor activity [Evidence IEA]; go_process: GO:0007264 - small GTPase mediated signal transduction [Evidence IEA] AKAW2_61210S COG:S; EggNog:ENOG410PPBC; InterPro:IPR006740; PFAM:PF04646 AKAW2_61211S COG:K; EggNog:ENOG410PPRB; InterPro:IPR036879,IPR033897,IPR002100; PFAM:PF00319; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0000987 - cis-regulatory region sequence-specific DNA binding [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0046983 - protein dimerization activity [Evidence IEA]; go_process: GO:0045944 - positive regulation of transcription by RNA polymerase II [Evidence IEA] AKAW2_61212A COG:S; EggNog:ENOG410PIYS; InterPro:IPR008521; PFAM:PF05653; TransMembrane:9 (o12-33i59-79o85-105i112-132o152-173i207-226o246-265i277- 298o304-326i); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0015095 - magnesium ion transmembrane transporter activity [Evidence IEA]; go_process: GO:0015693 - magnesium ion transport [Evidence IEA] AKAW2_61213S BUSCO:EOG09264OML; COG:C; EggNog:ENOG410PJA9; InterPro:IPR002842,IPR038495; PFAM:PF01991; go_component: GO:0033178 - proton-transporting two-sector ATPase complex, catalytic domain [Evidence IEA]; go_function: GO:0046961 - proton-transporting ATPase activity, rotational mechanism [Evidence IEA]; go_process: GO:1902600 - proton transmembrane transport [Evidence IEA] AKAW2_61214A COG:S; EggNog:ENOG410PN1K AKAW2_61215S COG:P; EggNog:ENOG410PG3H; InterPro:IPR026871,IPR018303,IPR023298,IPR023299, IPR001757,IPR023214,IPR006539,IPR036412,IPR008250, IPR032630,IPR032631; PFAM:PF13246,PF16209,PF00702,PF16212; TransMembrane:10 (i148-165o171-190i517-539o559-583i1136-1152o1164- 1185i1215-1236o1256-1274i1281-1301o1321-1341i); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0000166 - nucleotide binding [Evidence IEA]; go_function: GO:0000287 - magnesium ion binding [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0140326 - ATPase-coupled intramembrane lipid transporter activity [Evidence IEA]; go_process: GO:0015914 - phospholipid transport [Evidence IEA] AKAW2_61216S BUSCO:EOG092608AE; COG:A; EggNog:ENOG410PFUU; InterPro:IPR041677,IPR027417,IPR041679,IPR001878, IPR036875,IPR024481; PFAM:PF12726,PF13086,PF13245,PF13087,PF00580; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0004386 - helicase activity [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA] AKAW2_61217S COG:S; EggNog:ENOG410PZVV AKAW2_61218S COG:S; EggNog:ENOG410PQRF AKAW2_61219A COG:S; EggNog:ENOG410PQC9; InterPro:IPR012349; PFAM:PF13883; SECRETED:SignalP(1-25) AKAW2_61220A COG:S; EggNog:ENOG410PHG0; InterPro:IPR013922,IPR036915; go_function: GO:0019901 - protein kinase binding [Evidence IEA]; go_process: GO:0000079 - regulation of cyclin-dependent protein serine/threonine kinase activity [Evidence IEA] AKAW2_61221A TransMembrane:1 (i83-102o) AKAW2_61223A COG:S; EggNog:ENOG410PJU4; InterPro:IPR010497,IPR029058,IPR016292,IPR000639; MEROPS:MER0000432; PFAM:PF00561,PF06441; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0033961 - cis-stilbene-oxide hydrolase activity [Evidence IEA] AKAW2_61224A COG:E; EggNog:ENOG410QDDG; InterPro:IPR000192,IPR015424,IPR015421,IPR015422; PFAM:PF00266; go_function: GO:0003824 - catalytic activity [Evidence IEA] AKAW2_61222S COG:F,H; EggNog:ENOG410PI1W; InterPro:IPR038271,IPR001248; PFAM:PF02133; TransMembrane:12 (i45-69o75-99i111-133o171-187i194-215o235-253i273-295o315- 339i360-378o384-404i434-454o474-492i); go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_61225A COG:S; EggNog:ENOG410PJ2X; InterPro:IPR024679,IPR016024,IPR037947; PFAM:PF12333 AKAW2_61226A COG:K; EggNog:ENOG410PS1G; InterPro:IPR000679,IPR013088,IPR013860,IPR011420, IPR039355; PFAM:PF07573,PF00320,PF08550; go_component: GO:0005634 - nucleus [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0003700 - DNA-binding transcription factor activity [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_function: GO:0043565 - sequence-specific DNA binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA]; go_process: GO:0006357 - regulation of transcription by RNA polymerase II [Evidence IEA]; go_process: GO:0042128 - nitrate assimilation [Evidence IEA] AKAW2_61228A COG:S; EggNog:ENOG410PQE0; InterPro:IPR036864,IPR001138; PFAM:PF00172; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_61231A COG:K,L; EggNog:ENOG410PH18 AKAW2_61232A COG:Q; EggNog:ENOG410PKK4; InterPro:IPR002925,IPR029058; PFAM:PF01738; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_61233S COG:G; EggNog:ENOG410PFST; InterPro:IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i24-42o70-91i98-117o129-148i160-179o194-214i265-289o304- 323i330-350o356-378i390-412o424-445i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_61234S COG:C; EggNog:ENOG410PGZ7; InterPro:IPR011251,IPR016215,IPR036661; PFAM:PF00296; go_function: GO:0004497 - monooxygenase activity [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_61235S COG:K; EggNog:ENOG410PP1I; InterPro:IPR036236,IPR013087; PFAM:PF00096,PF13894 AKAW2_61236S COG:S; EggNog:ENOG410PSZT; SECRETED:SignalP(1-19) AKAW2_61237A COG:S; EggNog:ENOG410PJV2; InterPro:IPR036188; PFAM:PF07992,PF13738 AKAW2_61238S COG:S; EggNog:ENOG410PJRK; TransMembrane:7 (o6-30i42-65o102-124i136-160o180-205i217-243o249-270i) AKAW2_61239A COG:G; EggNog:ENOG410PISH; InterPro:IPR005828,IPR003663,IPR036259,IPR020846; PFAM:PF00083,PF07690; TransMembrane:12 (i48-66o97-117i124-142o154-172i184-204o216-236i306- 327o347-364i373-392o404-425i455-473o479-498i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_61240A COG:S; EggNog:ENOG410PZHF AKAW2_61241S COG:S; EggNog:ENOG410PZXR AKAW2_61242S COG:I; EggNog:ENOG410PJV3; InterPro:IPR019826,IPR002018,IPR029058; MEROPS:MER0030934; PFAM:PF00135,PF07859; SECRETED:SignalP(1-28) AKAW2_61243A COG:E; EggNog:ENOG410PNRU; InterPro:IPR036551,IPR003382,IPR004507; PFAM:PF02441; go_function: GO:0003824 - catalytic activity [Evidence IEA] AKAW2_61244S COG:H; EggNog:ENOG410PKET; InterPro:IPR032903,IPR002830; PFAM:PF01977; go_function: GO:0016831 - carboxy-lyase activity [Evidence IEA] AKAW2_61245S COG:S; EggNog:ENOG410PRHD; InterPro:IPR008547; PFAM:PF05705 AKAW2_61246S COG:F,P; EggNog:ENOG410PG6B; InterPro:IPR005829,IPR005828,IPR003663,IPR036259, IPR020846; PFAM:PF00083,PF07690; TransMembrane:11 (i52-79o99-118i125-145o151-172i184-207o213-234i306- 328o340-359i371-394o406-427i480-498o); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_61250A COG:I; EggNog:ENOG410PMEX; InterPro:IPR042098,IPR003819; PFAM:PF02668; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_61251A COG:S; EggNog:ENOG410PQRJ; InterPro:IPR011008,IPR013097; PFAM:PF07876 AKAW2_61252A COG:S; EggNog:ENOG410Q2Y5; InterPro:IPR011990,IPR019734; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_61253A COG:S; EggNog:ENOG410Q1ZA; InterPro:IPR036866,IPR001279; PFAM:PF13483,PF12706 AKAW2_61254S COG:G; EggNog:ENOG410PUCW; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:11 (n3-14c18/19o34-54i63-81o87-107i119-139o151-170i225- 249o261-283i304-323o329-351i363-385o397-419i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_61255S COG:S; EggNog:ENOG410PV6S; InterPro:IPR023213 AKAW2_61256S COG:S; EggNog:ENOG410PV6S; InterPro:IPR003480,IPR023213; go_function: GO:0016747 - transferase activity, transferring acyl groups other than amino-acyl groups [Evidence IEA] AKAW2_61257A COG:S; EggNog:ENOG410PV9W; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172; TransMembrane:1 (o524-545i); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_61258S COG:Z; EggNog:ENOG410PQ05; InterPro:IPR029006,IPR017904,IPR002108; PFAM:PF00241; go_component: GO:0015629 - actin cytoskeleton [Evidence IEA]; go_function: GO:0003779 - actin binding [Evidence IEA]; go_process: GO:0030042 - actin filament depolymerization [Evidence IEA] AKAW2_61259A COG:Q; EggNog:ENOG410PG3J; InterPro:IPR026992,IPR027443,IPR005123; PFAM:PF03171,PF14226; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_61260S COG:G; EggNog:ENOG410QDII; InterPro:IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i57-78o104-125i132-151o157-180i192-209o229-248i297- 316o336-355i360-381o387-407i419-436o456-477i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_61261A COG:M; EggNog:ENOG410PKAU; InterPro:IPR002110,IPR036770,IPR001810,IPR036047, IPR020683; PFAM:PF12796,PF00023,PF12937,PF13637,PF13606; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_61262S COG:S; EggNog:ENOG410PWX7 AKAW2_61263S COG:C; EggNog:ENOG410PWHG; InterPro:IPR023753,IPR001100,IPR004099,IPR036188, IPR016156; PFAM:PF02852,PF07992,PF00070; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_process: GO:0045454 - cell redox homeostasis [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_61264S COG:S; EggNog:ENOG410Q1VG AKAW2_61265A COG:S; EggNog:ENOG410PYFJ AKAW2_61266S COG:G; EggNog:ENOG410PU9C; InterPro:IPR011042,IPR017996; PFAM:PF03022; SECRETED:SignalP(1-19) AKAW2_61268S COG:Q; EggNog:ENOG410PJ01; InterPro:IPR001128,IPR017972,IPR002401,IPR036396; PFAM:PF00067; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_61271S COG:K; EggNog:ENOG410Q1WU; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_61272S COG:G; EggNog:ENOG410QDJ7; InterPro:IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i45-62o98-120i132-151o157-177i189-208o220-239i288- 312o324-346i353-371o383-403i415-435o447-469i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_61273A COG:P; EggNog:ENOG410PFVR; InterPro:IPR023271,IPR000292,IPR024002; PFAM:PF01226; TransMembrane:6 (i32-53o73-100i112-136o165-184i196-222o234-260i); go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_61274A COG:G; EggNog:ENOG410PFTW; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i71-91o111-128i140-161o167-186i198-219o231-252i304- 330o342-362i383-402o408-429i441-464o476-496i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_61275A COG:H; EggNog:ENOG410PG38; InterPro:IPR036144,IPR000926,IPR022163,IPR032677; PFAM:PF00925,PF12471; go_function: GO:0003935 - GTP cyclohydrolase II activity [Evidence IEA]; go_process: GO:0009231 - riboflavin biosynthetic process [Evidence IEA] AKAW2_61276A COG:S; EggNog:ENOG410PI0G; InterPro:IPR012469; PFAM:PF07958 AKAW2_61277S COG:F; EggNog:ENOG410PIZM; InterPro:IPR029057,IPR000836; PFAM:PF14681; go_process: GO:0009116 - nucleoside metabolic process [Evidence IEA] AKAW2_61278A COG:F; EggNog:ENOG410PF9P; InterPro:IPR029057,IPR000836; PFAM:PF14681; go_process: GO:0009116 - nucleoside metabolic process [Evidence IEA] AKAW2_61279S COG:C; EggNog:ENOG410PFAG; InterPro:IPR015590,IPR010061,IPR016160,IPR016161, IPR016162,IPR016163; PFAM:PF00171; go_function: GO:0004491 - methylmalonate-semialdehyde dehydrogenase (acylating) activity [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0016620 - oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_61280S COG:Q; EggNog:ENOG410PXC8; InterPro:IPR036291,IPR002347; PFAM:PF00106,PF13561; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_61282S COG:S; EggNog:ENOG410PJ95; InterPro:IPR043129 AKAW2_61283S COG:S; EggNog:ENOG410PK73; InterPro:IPR008775; PFAM:PF05721 AKAW2_61284A COG:S; EggNog:ENOG410PHWY; InterPro:IPR039535,IPR011047; PFAM:PF05935,PF14269; SECRETED:SignalP(1-19) AKAW2_61285S COG:G; EggNog:ENOG410PFI5; InterPro:IPR037524,IPR008979,IPR002772,IPR036881, IPR011658; PFAM:PF01915,PF07691; go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_61286A COG:S; EggNog:ENOG410PN0P; InterPro:IPR000073,IPR029058; PFAM:PF12697 AKAW2_61287A COG:Q; EggNog:ENOG410PVPB; InterPro:IPR013154,IPR013149,IPR002328,IPR036291, IPR011032,IPR020843; PFAM:PF00107,PF08240; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_61288S COG:S; EggNog:ENOG410PVHF; InterPro:IPR029063 AKAW2_61289S COG:S; EggNog:ENOG410PJVK AKAW2_61290S CAZy:GH16; COG:G; EggNog:ENOG410PJB2; InterPro:IPR000757,IPR013320,IPR017168; PFAM:PF00722; SECRETED:SignalP(1-20); TransMembrane:1 (n8-15c20/21o318-339i); go_component: GO:0005618 - cell wall [Evidence IEA]; go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_function: GO:0016798 - hydrolase activity, acting on glycosyl bonds [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA]; go_process: GO:0071555 - cell wall organization [Evidence IEA] AKAW2_61291A COG:K; EggNog:ENOG410Q1NG; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_61292S CAZy:GT25; COG:S; EggNog:ENOG410Q1SN; InterPro:IPR002654; PFAM:PF01755; TransMembrane:1 (i25-44o) AKAW2_61294S COG:E; EggNog:ENOG410PVP2; InterPro:IPR036052,IPR001926 AKAW2_61296S COG:E; EggNog:ENOG410PHU6; InterPro:IPR002293; PFAM:PF00324,PF13520; TransMembrane:12 (i46-65o77-100i121-147o167-187i199-220o259-276i297- 318o338-360i407-425o437-455i467-487o493-513i); go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_61297S COG:L; EggNog:ENOG410PR0Z; InterPro:IPR020084,IPR020476,IPR000086,IPR015797; PFAM:PF00293; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_61298A COG:S; EggNog:ENOG410PSCX AKAW2_61299S COG:S; EggNog:ENOG410PGSC AKAW2_61301S COG:I; EggNog:ENOG410PFS7; InterPro:IPR001199,IPR009160,IPR001522,IPR015876, IPR005804,IPR036400,IPR018506; PFAM:PF00173,PF00487; TransMembrane:5 (o36-55i62-82o94-116i177-196o202-228i); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0004768 - stearoyl-CoA 9-desaturase activity [Evidence IEA]; go_function: GO:0016717 - oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0006629 - lipid metabolic process [Evidence IEA]; go_process: GO:0006636 - unsaturated fatty acid biosynthetic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_61302S COG:Q; EggNog:ENOG410PMH2; InterPro:IPR013154,IPR013149,IPR002328,IPR036291, IPR011032,IPR029752,IPR020843; PFAM:PF00107,PF08240; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_61303A COG:S; EggNog:ENOG410PXTD AKAW2_61306A InterPro:IPR021109 AKAW2_61307S TransMembrane:6 (o20-44i65-85o97-119i140-160o180-202i235-257o); antiSMASH:Cluster_6.6 AKAW2_61308A COG:S; EggNog:ENOG410PQ1B; TransMembrane:7 (o15-34i46-71o91-112i124-145o165-188i200-222o234-257i); antiSMASH:Cluster_6.6 AKAW2_61309A antiSMASH:Cluster_6.6 AKAW2_61310S COG:E; EggNog:ENOG410Q241; InterPro:IPR002293; PFAM:PF00324,PF13520; SMCOG1038:phenylalanine-specific permease; TransMembrane:12 (i43-66o78-96i124-148o168-186i198-216o236-256i277-303o323- 348i384-405o411-429i463-486o498-517i); antiSMASH:Cluster_6.6; go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_61311S CAZy:AA3; COG:E; EggNog:ENOG410PVHT; InterPro:IPR012132,IPR036188,IPR000172,IPR007867; PFAM:PF05199,PF00732; antiSMASH:Cluster_6.6; go_function: GO:0016614 - oxidoreductase activity, acting on CH-OH group of donors [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_61312A SECRETED:SignalP(1-29); TransMembrane:1 (n14-25c29/30o203-226i); antiSMASH:Cluster_6.6 AKAW2_61313S COG:S; EggNog:ENOG410PP0G; InterPro:IPR006680,IPR032466,IPR032465; PFAM:PF04909; antiSMASH:Cluster_6.6; go_function: GO:0016787 - hydrolase activity [Evidence IEA]; go_function: GO:0016831 - carboxy-lyase activity [Evidence IEA] AKAW2_61314A COG:Q; EggNog:ENOG410PJKV; InterPro:IPR036291,IPR002347; PFAM:PF08659,PF00106,PF13561; SMCOG1001:short-chain dehydrogenase/reductase SDR; antiSMASH:Cluster_6.6; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_61315A InterPro:IPR022085; PFAM:PF12311; antiSMASH:Cluster_6.6 AKAW2_61316A COG:I; EggNog:ENOG410PJU0; InterPro:IPR000873,IPR009081,IPR036736,IPR036291, IPR013120,IPR042099,IPR020845; PFAM:PF00501,PF00550,PF01370,PF07993; SMCOG1010:NAD-dependent epimerase/dehydratase; antiSMASH:Cluster_6.6 AKAW2_61317A COG:H; EggNog:ENOG410PI3Z; InterPro:IPR003710,IPR013752,IPR013332,IPR008927, IPR013328; PFAM:PF02558,PF08546; antiSMASH:Cluster_6.6; go_function: GO:0008677 - 2-dehydropantoate 2-reductase activity [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0015940 - pantothenate biosynthetic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_61318S COG:S; EggNog:ENOG410PUZ2; InterPro:IPR036864,IPR021858,IPR001138; PFAM:PF00172,PF11951; antiSMASH:Cluster_6.6; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_61319A COG:T,Z; EggNog:ENOG410PJ5R; InterPro:IPR036409,IPR001303; PFAM:PF00596; antiSMASH:Cluster_6.6 AKAW2_61320S COG:E; EggNog:ENOG410QDM5; InterPro:IPR004841; PFAM:PF13520,PF00324; SMCOG1038:phenylalanine-specific permease; TransMembrane:12 (i36-60o66-85i97-119o125-142i154-175o208-228i248-266o300- 319i345-362o374-397i418-440o446-465i); antiSMASH:Cluster_6.6; go_component: GO:0016020 - membrane [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_61321A COG:C; EggNog:ENOG410PKHE; InterPro:IPR012133,IPR037396,IPR008259,IPR013785, IPR000262; PFAM:PF01070; antiSMASH:Cluster_6.6; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0010181 - FMN binding [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_61322S COG:Q; EggNog:ENOG410PWDT; InterPro:IPR001613,IPR036188,IPR002937; PFAM:PF13450,PF01593; antiSMASH:Cluster_6.6; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_61323S COG:G; EggNog:ENOG410PW2N; InterPro:IPR003378; SECRETED:SignalP(1-22); antiSMASH:Cluster_6.6; go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0016757 - transferase activity, transferring glycosyl groups [Evidence IEA] AKAW2_61324A SECRETED:SignalP(1-19); antiSMASH:Cluster_6.6 AKAW2_61325A COG:S; EggNog:ENOG410PHWY; InterPro:IPR039535; PFAM:PF05935,PF14269; SECRETED:SignalP(1-20); antiSMASH:Cluster_6.6 AKAW2_61326A COG:G; EggNog:ENOG410PFT2; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i36-56o76-93i105-124o136-153i165-186o198-220i269-289o309- 326i333-353o365-386i398-417o429-450i); antiSMASH:Cluster_6.6; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_61327A SECRETED:SignalP(1-22) AKAW2_61328S COG:S; EggNog:ENOG410PMN4; InterPro:IPR021765; PFAM:PF11807; TransMembrane:1 (i93-114o); go_process: GO:0043386 - mycotoxin biosynthetic process [Evidence IEA] AKAW2_61329S COG:Q; EggNog:ENOG410PIRX; InterPro:IPR026992,IPR027443,IPR005123; PFAM:PF03171,PF14226; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_61330S COG:K; EggNog:ENOG410PSSN; InterPro:IPR002112,IPR004827; PFAM:PF00170,PF07716; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0003700 - DNA-binding transcription factor activity [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_61331A COG:S; EggNog:ENOG410PSQJ; InterPro:IPR019626; PFAM:PF10685 AKAW2_61332A COG:C,H; EggNog:ENOG410Q2BI; InterPro:IPR036188,IPR002938,IPR036249,IPR038220, IPR012941; PFAM:PF07976,PF01494; go_function: GO:0071949 - FAD binding [Evidence IEA] AKAW2_61333A TransMembrane:1 (o42-63i) AKAW2_61335S COG:S; EggNog:ENOG410PFQ6; TransMembrane:4 (i83-111o131-153i191-211o648-669i) AKAW2_61336S COG:G; EggNog:ENOG410PVPJ; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:11 (o16-38i45-63o75-97i104-123o135-154i240-263o283-305i326- 347o353-378i390-409o421-443i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_61337A COG:S; EggNog:ENOG410PXB4; TransMembrane:7 (o12-30i42-74o94-119i131-158o178-197i209-229o241-262i) AKAW2_61338S COG:P; EggNog:ENOG410PFZ2; InterPro:IPR004698,IPR003689; PFAM:PF02535; TransMembrane:8 (o38-58i70-90o110-134i200-219o231-252i264-283o295-314i335- 353o); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0005385 - zinc ion transmembrane transporter activity [Evidence IEA]; go_function: GO:0046873 - metal ion transmembrane transporter activity [Evidence IEA]; go_process: GO:0030001 - metal ion transport [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA]; go_process: GO:0071577 - zinc ion transmembrane transport [Evidence IEA] AKAW2_61339A COG:Q; EggNog:ENOG410PFNG; InterPro:IPR001128,IPR002403,IPR036396; PFAM:PF00067; TransMembrane:1 (o6-27i); go_function: GO:0004497 - monooxygenase activity [Evidence IEA]; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_61340S COG:S; EggNog:ENOG410PIUG AKAW2_61341S InterPro:IPR011008,IPR009799; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA] AKAW2_61342A COG:S; EggNog:ENOG410Q2BG; SECRETED:SignalP(1-19) AKAW2_61343A COG:S; EggNog:ENOG410Q22F AKAW2_61344A COG:S; EggNog:ENOG410Q1Z1; SECRETED:SignalP(1-18); TransMembrane:1 (n5-16c23/24o310-339i) AKAW2_61347A CAZy:GT2_Chitin_synth; COG:M; EggNog:ENOG410Q28A; InterPro:IPR029044,IPR004835,IPR004834,IPR013616; PFAM:PF01644,PF08407; TransMembrane:8 (o521-540i552-575o609-626i638-663o683-709i721-739o819- 839i860-881o); go_function: GO:0004100 - chitin synthase activity [Evidence IEA]; go_function: GO:0016758 - transferase activity, transferring hexosyl groups [Evidence IEA]; go_process: GO:0006031 - chitin biosynthetic process [Evidence IEA] AKAW2_61348A SECRETED:SignalP(1-29); TransMembrane:2 (i9-27o62-82i) AKAW2_61349A COG:G; EggNog:ENOG410Q2VQ; InterPro:IPR011118,IPR029058; PFAM:PF07519; SECRETED:SignalP(1-17) AKAW2_61351A COG:S; EggNog:ENOG410PVPD; InterPro:IPR021838; PFAM:PF11913; TransMembrane:1 (i9-25o) AKAW2_61352A COG:M; EggNog:ENOG410PM6B; InterPro:IPR036291,IPR001509; PFAM:PF16363,PF01370; go_function: GO:0003824 - catalytic activity [Evidence IEA] AKAW2_61353A CAZy:GH135; COG:S; EggNog:ENOG410PRJ3; InterPro:IPR021986; PFAM:PF12138 AKAW2_61354A CAZy:GH135; COG:U; EggNog:ENOG410Q1SW; InterPro:IPR021986; PFAM:PF12138; TransMembrane:1 (i12-37o) AKAW2_61355S COG:M; EggNog:ENOG410PKT7; InterPro:IPR001296; PFAM:PF00534,PF13692; TransMembrane:12 (o24-45i848-869o889-913i925-946o952-978i990-1008o1014- 1031i1268-1289o1295-1312i1324-1341o1347-1369i1756-1773o) AKAW2_61356A COG:S; EggNog:ENOG410PSUX AKAW2_61357S COG:S; EggNog:ENOG410PTF7 AKAW2_61358S COG:S; EggNog:ENOG410PIST; InterPro:IPR022124; PFAM:PF12396; TransMembrane:1 (o952-974i) AKAW2_61359S COG:L; EggNog:ENOG410PIMX; InterPro:IPR041677,IPR000967,IPR027417,IPR041679; PFAM:PF13245,PF13086,PF13087; go_component: GO:0005634 - nucleus [Evidence IEA]; go_function: GO:0003700 - DNA-binding transcription factor activity [Evidence IEA]; go_function: GO:0004386 - helicase activity [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_61360S COG:S; EggNog:ENOG410PVKC; InterPro:IPR036291,IPR001509; PFAM:PF01370; go_function: GO:0003824 - catalytic activity [Evidence IEA] AKAW2_61361A COG:E; EggNog:ENOG410PHDU; InterPro:IPR002933,IPR010158,IPR011650,IPR036264; MEROPS:MER0026469; PFAM:PF01546,PF07687; go_function: GO:0016787 - hydrolase activity [Evidence IEA]; go_function: GO:0016813 - hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines [Evidence IEA] AKAW2_61362S COG:E; EggNog:ENOG410PHTK; InterPro:IPR002933,IPR001926,IPR036052,IPR011650, IPR036264; MEROPS:MER0003798; PFAM:PF00291,PF01546,PF07687; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_61363S COG:K; EggNog:ENOG410PUGU; InterPro:IPR008422,IPR001356,IPR009057,IPR017970, IPR013087; PFAM:PF00046,PF05920; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_61364A COG:T; EggNog:ENOG410PJCP; InterPro:IPR001789,IPR003594,IPR003661,IPR036890, IPR036097,IPR011006,IPR004358,IPR005467; PFAM:PF00512,PF02518,PF00072; go_function: GO:0000155 - phosphorelay sensor kinase activity [Evidence IEA]; go_function: GO:0016772 - transferase activity, transferring phosphorus-containing groups [Evidence IEA]; go_process: GO:0000160 - phosphorelay signal transduction system [Evidence IEA]; go_process: GO:0007165 - signal transduction [Evidence IEA]; go_process: GO:0016310 - phosphorylation [Evidence IEA] AKAW2_61365S COG:G,Q; EggNog:ENOG410PIZS; InterPro:IPR036291,IPR000683; PFAM:PF01408; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA] AKAW2_61366A COG:S; EggNog:ENOG410PP0M; InterPro:IPR036291,IPR016040; PFAM:PF05368 AKAW2_61367S COG:G,M; EggNog:ENOG410PNHV; InterPro:IPR036291,IPR008030; PFAM:PF08659,PF13460,PF05368 AKAW2_61368A COG:S; EggNog:ENOG410Q1RX; InterPro:IPR013126,IPR043129; SECRETED:SignalP(1-21) AKAW2_61369A COG:S; EggNog:ENOG410Q2YA AKAW2_61370A COG:V; EggNog:ENOG410PK8P; InterPro:IPR036291 AKAW2_61371A COG:V; EggNog:ENOG410PK8P; InterPro:IPR036291,IPR016040 AKAW2_61372S COG:K; EggNog:ENOG410PHTN; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; antiSMASH:Cluster_6.7; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_61373A COG:G; EggNog:ENOG410PK5W; InterPro:IPR041792,IPR029052,IPR039331,IPR025733, IPR004843,IPR008963,IPR015914; PFAM:PF16656,PF00149,PF14008; SECRETED:SignalP(1-20); antiSMASH:Cluster_6.7; go_function: GO:0003993 - acid phosphatase activity [Evidence IEA]; go_function: GO:0016787 - hydrolase activity [Evidence IEA]; go_function: GO:0046872 - metal ion binding [Evidence IEA] AKAW2_61374A COG:S; EggNog:ENOG410PGF6; InterPro:IPR036291,IPR008030; PFAM:PF05368,PF03435; antiSMASH:Cluster_6.7 AKAW2_61375A COG:S; EggNog:ENOG410PSC9; InterPro:IPR023393; antiSMASH:Cluster_6.7 AKAW2_61376S COG:K; EggNog:ENOG410PVHN; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; TransMembrane:1 (o614-632i); antiSMASH:Cluster_6.7; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_61377S COG:S; EggNog:ENOG410PUM1; InterPro:IPR008949; PFAM:PF19086; SMCOG1052:Terpene synthase/cyclase metal-binding domain protein; antiSMASH:Cluster_6.7 AKAW2_61378S COG:C,H; EggNog:ENOG410PKIW; InterPro:IPR036188,IPR002938; antiSMASH:Cluster_6.7; go_function: GO:0071949 - FAD binding [Evidence IEA] AKAW2_61379S COG:U; EggNog:ENOG410PV75; InterPro:IPR036188,IPR002938; SMCOG1087:hypothetical protein; antiSMASH:Cluster_6.7; go_function: GO:0071949 - FAD binding [Evidence IEA] AKAW2_61380A COG:S; EggNog:ENOG410PWY3; InterPro:IPR040410; TransMembrane:2 (n2-13c17/18o27-46i58-83o); antiSMASH:Cluster_6.7 AKAW2_61381A COG:S; EggNog:ENOG410PNW1; InterPro:IPR012312; PFAM:PF01814; antiSMASH:Cluster_6.7 AKAW2_61382S COG:P; EggNog:ENOG410PGR0; InterPro:IPR018028,IPR011614,IPR024708,IPR020835, IPR024711,IPR037060,IPR010582; PFAM:PF00199,PF06628; go_function: GO:0004096 - catalase activity [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0006979 - response to oxidative stress [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_61383S COG:S; EggNog:ENOG410PHCG; InterPro:IPR025533; PFAM:PF14388 AKAW2_61384S SECRETED:SignalP(1-20) AKAW2_61385A COG:Q; EggNog:ENOG410PIXU; InterPro:IPR015889; SECRETED:SignalP(1-20); go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016702 - oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_61386S COG:K; EggNog:ENOG410Q2P7; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; TransMembrane:1 (o531-550i); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_70002A CAZy:CE1; InterPro:IPR000801,IPR029058 AKAW2_70003A COG:S; EggNog:ENOG410PRJN; SECRETED:SignalP(1-25); TransMembrane:2 (n6-17c25/26o260-280i301-322o) AKAW2_70005S COG:G; EggNog:ENOG410PFE6; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690,PF00083; TransMembrane:12 (i55-76o88-109i121-140o146-168i180-201o207-229i284- 303o323-342i362-381o387-409i421-443o455-475i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_70006A COG:S; EggNog:ENOG410PSV3; InterPro:IPR011057,IPR006913; PFAM:PF04828; go_function: GO:0016846 - carbon-sulfur lyase activity [Evidence IEA] AKAW2_70007S COG:G; EggNog:ENOG410PPJ5; InterPro:IPR000771,IPR013785; PFAM:PF01116; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_function: GO:0016832 - aldehyde-lyase activity [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_70008A COG:C; EggNog:ENOG410PK7G; InterPro:IPR043144,IPR036111,IPR043143,IPR003767; PFAM:PF02615; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_70009A COG:S; EggNog:ENOG410PX9Z; InterPro:IPR011008,IPR013097; PFAM:PF07876 AKAW2_70010S COG:G; EggNog:ENOG410PHFT; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:10 (i46-63o87-109i116-136o142-164i176-197o209-232i281- 301o313-335i347-365o371-392i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_70011S COG:G; EggNog:ENOG410PHFT; TransMembrane:1 (o22-47i) AKAW2_70012A COG:H; EggNog:ENOG410PM39; InterPro:IPR005493,IPR036704; PFAM:PF03737 AKAW2_70013A COG:S; EggNog:ENOG410PPIN; InterPro:IPR007219; PFAM:PF04082; TransMembrane:1 (o598-620i); go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA] AKAW2_70014S COG:S; EggNog:ENOG410PRJP; InterPro:IPR006680,IPR032466; PFAM:PF04909; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_70015A COG:S; EggNog:ENOG410PPCP AKAW2_70016A COG:G; EggNog:ENOG410PGUV; InterPro:IPR016040,IPR036291,IPR020904; PFAM:PF04321,PF01073,PF16363,PF13460,PF01370; TransMembrane:1 (o20-39i); go_function: GO:0016491 - oxidoreductase activity [Evidence IEA] AKAW2_70017S COG:U; EggNog:ENOG410PJXX; InterPro:IPR020846,IPR001958,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i12-35o55-74i86-108o114-132i144-166o172-192i231-256o276- 296i303-324o336-359i380-399o405-427i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_70018A COG:G,Q; EggNog:ENOG410PKW7; InterPro:IPR036291,IPR000683; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA] AKAW2_70019S COG:E; EggNog:ENOG410PW1Q; InterPro:IPR000653,IPR012749,IPR015424,IPR015421, IPR015422; PFAM:PF01041; antiSMASH:Cluster_7.1; go_function: GO:0003824 - catalytic activity [Evidence IEA] AKAW2_70020A COG:S; EggNog:ENOG410PZTD; TransMembrane:4 (i12-36o42-61i107-124o174-194i); antiSMASH:Cluster_7.1 AKAW2_70021S COG:G; EggNog:ENOG410PIRP; InterPro:IPR023271,IPR000425; PFAM:PF00230; TransMembrane:5 (o397-428i440-459o487-511i523-541o573-593i); antiSMASH:Cluster_7.1; go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0015267 - channel activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_70022S COG:I; EggNog:ENOG410Q2DC; InterPro:IPR004695,IPR030185; PFAM:PF03595; TransMembrane:10 (i21-40o52-73i104-126o132-159i171-192o204-223i244-265o285- 312i324-341o361-380i); antiSMASH:Cluster_7.1; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0015140 - malate transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA]; go_process: GO:0071423 - malate transmembrane transport [Evidence IEA] AKAW2_70023A COG:I; EggNog:ENOG410PV7T; InterPro:IPR036273,IPR001251,IPR036865; PFAM:PF00650; antiSMASH:Cluster_7.1 AKAW2_70024S COG:H; EggNog:ENOG410PK7M; InterPro:IPR033749,IPR008949,IPR000092; PFAM:PF19086,PF00348; SMCOG1182:Polyprenyl synthetase; antiSMASH:Cluster_7.1; go_process: GO:0008299 - isoprenoid biosynthetic process [Evidence IEA] AKAW2_70025A COG:S; EggNog:ENOG410PNJ6; TransMembrane:6 (o28-46i67-86o168-186i198-219o311-331i338-360o); antiSMASH:Cluster_7.1 AKAW2_70026S COG:Q; EggNog:ENOG410PG4C; InterPro:IPR002925,IPR029058; PFAM:PF01738; antiSMASH:Cluster_7.1; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_70027A COG:E; EggNog:ENOG410PHHD; InterPro:IPR013057; PFAM:PF01490; TransMembrane:11 (i58-77o83-103i134-154o160-181i188-212o232-253i265- 286o306-327i347-367o379-401i413-435o); antiSMASH:Cluster_7.1 AKAW2_70028S COG:S; EggNog:ENOG410PTJQ; antiSMASH:Cluster_7.1 AKAW2_70029S antiSMASH:Cluster_7.1 AKAW2_70030A COG:S; EggNog:ENOG410PMUI; InterPro:IPR007219; PFAM:PF04082; TransMembrane:6 (i198-221o241-257i278-306o312-330i537-556o571-588i); go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA] AKAW2_70031S COG:C,H; EggNog:ENOG410PW9G; InterPro:IPR036188,IPR002938; PFAM:PF01494; go_function: GO:0071949 - FAD binding [Evidence IEA] AKAW2_70032S COG:Q; EggNog:ENOG410PH61; InterPro:IPR013154,IPR013149,IPR002328,IPR036291, IPR011032,IPR020843; PFAM:PF00107,PF08240; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_70033A COG:Q; EggNog:ENOG410PFM9; InterPro:IPR013154,IPR013149,IPR014189,IPR036291, IPR011032,IPR020843; PFAM:PF00107,PF08240,PF13602; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_70034S COG:T,Z; EggNog:ENOG410PKFB; InterPro:IPR036409,IPR001303; PFAM:PF00596 AKAW2_70035A COG:S; EggNog:ENOG410PUWP; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; TransMembrane:1 (o502-521i); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_70036A COG:S; EggNog:ENOG410PI90; InterPro:IPR036291,IPR008030; PFAM:PF13460,PF05368; antiSMASH:Cluster_7.2 AKAW2_70037A COG:S; EggNog:ENOG410PRJP; InterPro:IPR006680,IPR032466; PFAM:PF04909; antiSMASH:Cluster_7.2; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_70038S COG:G; EggNog:ENOG410PF8Z; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690,PF00083; SMCOG1106:major facilitator transporter; TransMembrane:7 (o46-67i111-129o149-170i177-195o201-224i236-255o275-296i); antiSMASH:Cluster_7.2; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_70039S COG:C; EggNog:ENOG410Q1S7; InterPro:IPR036188,IPR002938; PFAM:PF01494; SMCOG1087:hypothetical protein; antiSMASH:Cluster_7.2; go_function: GO:0071949 - FAD binding [Evidence IEA] AKAW2_70040S COG:L; EggNog:ENOG410PUC8; InterPro:IPR032466,IPR001130; PFAM:PF01026; antiSMASH:Cluster_7.2; go_function: GO:0016788 - hydrolase activity, acting on ester bonds [Evidence IEA] AKAW2_70041A CAZy:GH95; COG:S; EggNog:ENOG410PK1W; InterPro:IPR008928,IPR027414,IPR016518,IPR013780, IPR012341; PFAM:PF14498; SECRETED:SignalP(1-17); antiSMASH:Cluster_7.2; go_function: GO:0004560 - alpha-L-fucosidase activity [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_70042A COG:E; EggNog:ENOG410PM73; InterPro:IPR036526,IPR044149,IPR000132,IPR003010; PFAM:PF00795; SMCOG1294:Nitrilase/cyanide hydratase and apolipoprotein; antiSMASH:Cluster_7.2; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_process: GO:0006807 - nitrogen compound metabolic process [Evidence IEA] AKAW2_70043S COG:Q; EggNog:ENOG410Q2HE; InterPro:IPR000873,IPR009081,IPR036291,IPR036736, IPR010080,IPR013120,IPR042099,IPR020845; PFAM:PF00501,PF00550,PF01370,PF07993; SMCOG1002:AMP-dependent synthetase and ligase; TransMembrane:1 (o653-671i); antiSMASH:Cluster_7.2 AKAW2_70044A COG:G; EggNog:ENOG410QDIB; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; SMCOG1106:major facilitator transporter; TransMembrane:11 (o32-56i68-85o105-121i128-148o160-179i191-211o297-316i323- 343o355-375i387-407o419-440i); antiSMASH:Cluster_7.2; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_70045A COG:O; EggNog:ENOG410PI0U; InterPro:IPR036188; PFAM:PF13450; SECRETED:SignalP(1-24); antiSMASH:Cluster_7.2 AKAW2_70046A COG:S; EggNog:ENOG410PPM4; SECRETED:SignalP(1-20); antiSMASH:Cluster_7.2 AKAW2_70047A COG:S; EggNog:ENOG410PN5J; InterPro:IPR007568; PFAM:PF04479; TransMembrane:7 (o12-31i38-61o73-93i114-138o150-172i197-217o229-249i); antiSMASH:Cluster_7.2; go_component: GO:0016021 - integral component of membrane [Evidence IEA] AKAW2_70048A antiSMASH:Cluster_7.2 AKAW2_70049A COG:C; EggNog:ENOG410PFPQ; InterPro:IPR036188,IPR006076,IPR017941,IPR034789, IPR036922,IPR038010; PFAM:PF01266,PF13450,PF00355; SMCOG1103:FAD dependent oxidoreductase; antiSMASH:Cluster_7.2; go_function: GO:0004022 - alcohol dehydrogenase (NAD+) activity [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0051537 - 2 iron, 2 sulfur cluster binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_70050S COG:S; EggNog:ENOG410PJBN; InterPro:IPR007736,IPR011992,IPR002048,IPR018247; PFAM:PF00036,PF05042; TransMembrane:1 (o111-129i); antiSMASH:Cluster_7.2; go_function: GO:0005509 - calcium ion binding [Evidence IEA] AKAW2_70051A COG:G; EggNog:ENOG410QDIV; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; SMCOG1106:major facilitator transporter; TransMembrane:12 (i41-59o79-100i107-127o133-155i167-188o200-226i273- 296o308-328i340-360o366-387i399-419o431-455i); antiSMASH:Cluster_7.2; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_70052A COG:G; EggNog:ENOG410QDHI; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:11 (o34-52i81-102o108-127i139-160o204-227i273-295o315- 334i346-364o376-394i406-429o441-460i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_70053A COG:G,M; EggNog:ENOG410PUNB; InterPro:IPR036291,IPR008030; PFAM:PF13460,PF05368 AKAW2_70054A COG:K; EggNog:ENOG410PHTN; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_70055A COG:S; EggNog:ENOG410PFWF; InterPro:IPR007461,IPR033643; PFAM:PF04366 AKAW2_70056A COG:G; EggNog:ENOG410Q1QQ; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i104-128o140-158i170-188o200-221i228-248o260-280i336- 358o370-394i415-437o443-468i475-497o509-531i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_70057A COG:T; EggNog:ENOG410PFPV; InterPro:IPR004813,IPR004648; PFAM:PF03169; TransMembrane:16 (o85-105i112-130o158-180i192-210o216-235i255-272o328- 351i406-425o458-475i482-500o512-528i567-587o639-657i664- 680o686-703i715-738o); go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_70058S COG:S; EggNog:ENOG410PQBQ; InterPro:IPR021833; PFAM:PF11905 AKAW2_70059A TransMembrane:1 (o20-36i) AKAW2_70060S COG:S; EggNog:ENOG410PQE3; InterPro:IPR013857,IPR039131,IPR008979; PFAM:PF08547; go_process: GO:0032981 - mitochondrial respiratory chain complex I assembly [Evidence IEA] AKAW2_70061A COG:S; EggNog:ENOG410PQ7C; InterPro:IPR011761,IPR003806; PFAM:PF13535,PF02655; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0046872 - metal ion binding [Evidence IEA] AKAW2_70062S TransMembrane:1 (i36-56o) AKAW2_70063S COG:S; EggNog:ENOG410PJKU; InterPro:IPR011059,IPR013108,IPR032466; PFAM:PF07969,PF01979; go_function: GO:0016810 - hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [Evidence IEA] AKAW2_70064S COG:S; EggNog:ENOG410PW2Q; InterPro:IPR029058 AKAW2_70065S COG:C; EggNog:ENOG410PHJW; InterPro:IPR044152,IPR001155,IPR013785; PFAM:PF00724; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0003959 - NADPH dehydrogenase activity [Evidence IEA]; go_function: GO:0010181 - FMN binding [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0050661 - NADP binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_70066S COG:O; EggNog:ENOG410PP0P; InterPro:IPR013740,IPR036249,IPR037944,IPR013766; PFAM:PF08534,PF00578; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA] AKAW2_70068S COG:S; EggNog:ENOG410PNCK; InterPro:IPR002818,IPR029062; MEROPS:MER0034659; PFAM:PF01965 AKAW2_70067A COG:G; EggNog:ENOG410Q1QE; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:9 (o29-57i78-98o110-129i179-202o222-241i262-280o292-309i321- 346o358-380i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_70069S COG:Z; EggNog:ENOG410PGZB; InterPro:IPR036180,IPR007122,IPR007123,IPR029006; PFAM:PF00626; go_function: GO:0051015 - actin filament binding [Evidence IEA] AKAW2_70071A COG:S; EggNog:ENOG410PWPT; InterPro:IPR036864,IPR021858,IPR001138; PFAM:PF00172,PF11951; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_70072S COG:S; EggNog:ENOG410Q08V; InterPro:IPR036291,IPR008030; PFAM:PF13460,PF05368 AKAW2_70073A COG:G; EggNog:ENOG410PFT2; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:11 (o45-66i120-139o145-167i179-201o213-234i282-303o315- 338i345-367o373-393i405-426o432-456i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_70074S COG:S; EggNog:ENOG410PHXD; InterPro:IPR009906,IPR038021; PFAM:PF07286 AKAW2_70075A COG:K; EggNog:ENOG410Q1AK; InterPro:IPR036864,IPR000704,IPR007219,IPR001138; PFAM:PF00172; TransMembrane:3 (i275-297o309-330i546-564o); go_component: GO:0005956 - protein kinase CK2 complex [Evidence IEA]; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_function: GO:0019887 - protein kinase regulator activity [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_70076A COG:Q; EggNog:ENOG410PJG6; InterPro:IPR001128,IPR002401,IPR036396; PFAM:PF00067; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_70078A COG:G; EggNog:ENOG410PHMI; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:8 (i196-214o226-247i303-330o336-361i382-402o408-432i453- 473o479-502i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_70079A COG:S; EggNog:ENOG410PQHJ; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_70080A COG:Q; EggNog:ENOG410QED1; InterPro:IPR036291,IPR002347; PFAM:PF08659,PF00106,PF13561; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_70081S COG:S; EggNog:ENOG410PUJM; InterPro:IPR010497,IPR029058; MEROPS:MER0000432; PFAM:PF06441 AKAW2_70082S COG:S; EggNog:ENOG410PUJM; InterPro:IPR029058; MEROPS:MER0000432 AKAW2_70083S COG:S; EggNog:ENOG410PXK8; InterPro:IPR036864,IPR021858,IPR001138; PFAM:PF00172; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_70084A COG:S; EggNog:ENOG410PMZJ; InterPro:IPR038921 AKAW2_70085A COG:P; EggNog:ENOG410PFYA; InterPro:IPR004923; PFAM:PF03239; TransMembrane:7 (o6-32i52-76o88-109i147-168o180-199i211-231o296-315i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0033573 - high-affinity iron permease complex [Evidence IEA]; go_function: GO:0005381 - iron ion transmembrane transporter activity [Evidence IEA]; go_process: GO:0034755 - iron ion transmembrane transport [Evidence IEA] AKAW2_70086S COG:P,Q; EggNog:ENOG410PHSN; InterPro:IPR013112,IPR017927,IPR013130,IPR013121, IPR039261; PFAM:PF08022,PF01794,PF08030; SECRETED:SignalP(1-20); TransMembrane:6 (n5-15c20/21o219-240i310-330o353-371i391-412o424-446i453- 470o); go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_70088A COG:S; EggNog:ENOG410PYH9; TransMembrane:6 (o36-57i69-89o118-135i147-167o187-211i223-245o) AKAW2_70089A COG:Q; EggNog:ENOG410PKHI; InterPro:IPR001447,IPR038765; PFAM:PF00797; go_function: GO:0016407 - acetyltransferase activity [Evidence IEA] AKAW2_70090S COG:E; EggNog:ENOG410PG5N; InterPro:IPR002293; PFAM:PF00324,PF13520; TransMembrane:12 (i39-61o73-93i105-125o131-156i168-188o194-214i269-294o327- 346i378-398o404-428i449-468o480-499i); go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_70091A COG:S; EggNog:ENOG410Q211; TransMembrane:7 (o12-33i45-69o89-111i123-144o167-193i205-225o245-267i) AKAW2_70092S COG:S; EggNog:ENOG410PK7P; InterPro:IPR001077,IPR036388,IPR016461,IPR029063, IPR036390; PFAM:PF00891; go_function: GO:0008168 - methyltransferase activity [Evidence IEA]; go_function: GO:0008171 - O-methyltransferase activity [Evidence IEA] AKAW2_70093A COG:I; EggNog:ENOG410PIPV; InterPro:IPR036188,IPR002938; TransMembrane:1 (o12-29i); go_function: GO:0071949 - FAD binding [Evidence IEA] AKAW2_70094A COG:S; EggNog:ENOG410PKP8; TransMembrane:7 (o16-35i47-71o91-109i121-143o163-184i200-220o240-265i) AKAW2_70095S COG:G; EggNog:ENOG410QDX4; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:11 (o31-49i61-77o97-116i123-146o152-172i227-249o269-290i311- 335o341-365i377-396o408-431i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_70096S COG:S; EggNog:ENOG410Q2R9; SECRETED:SignalP(1-28); TransMembrane:4 (n10-23c35/36o51-79i193-215o235-264i330-348o) AKAW2_70097A COG:E,H; EggNog:ENOG410Q1KX; InterPro:IPR012001,IPR012000,IPR011766,IPR029061, IPR029035; PFAM:PF02775,PF02776,PF00205; go_function: GO:0000287 - magnesium ion binding [Evidence IEA]; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0030976 - thiamine pyrophosphate binding [Evidence IEA] AKAW2_70098A COG:S; EggNog:ENOG410Q2K7; TransMembrane:7 (o15-36i48-73o93-116i128-149o177-196i208-227o247-265i) AKAW2_70099A COG:G; EggNog:ENOG410PVW0; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i33-50o74-96i103-120o126-150i162-184o196-216i255-274o304- 321i328-344o356-379i391-410o422-442i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_70100S COG:S; EggNog:ENOG410PQZZ; InterPro:IPR004360,IPR037523,IPR029068; PFAM:PF00903 AKAW2_70101A COG:S; EggNog:ENOG410PS9A; InterPro:IPR039438,IPR039713,IPR007513,IPR026939; PFAM:PF04419,PF12907 AKAW2_70102S COG:S; EggNog:ENOG410PUGZ; InterPro:IPR036465 AKAW2_70104S COG:S; EggNog:ENOG410Q2T6; InterPro:IPR036864,IPR001138; PFAM:PF00172; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_70105S COG:S; EggNog:ENOG410Q2T6 AKAW2_70106A COG:S; EggNog:ENOG410PX83; TransMembrane:7 (o12-29i36-55o67-87i99-122o134-155i167-192o212-229i) AKAW2_70107S COG:S; EggNog:ENOG410Q2VU; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; TransMembrane:1 (i181-199o); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_70108S COG:S; EggNog:ENOG410Q2K5; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; TransMembrane:2 (o582-599i632-650o); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_70109S COG:S; EggNog:ENOG410PUBY; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; TransMembrane:3 (i253-273o331-348i369-386o); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_70110S COG:Q; EggNog:ENOG410PJNG; InterPro:IPR036640; TransMembrane:2 (i36-55o75-97i); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA] AKAW2_70111S COG:Q; EggNog:ENOG410PJNG; InterPro:IPR017871,IPR027417,IPR003593,IPR011527, IPR003439,IPR036640; PFAM:PF00005,PF00664; TransMembrane:6 (i28-54o66-87i402-423o438-459i530-552o612-638i); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA]; go_function: GO:0042626 - ATPase-coupled transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_70112A COG:A; EggNog:ENOG410PIUX; InterPro:IPR027417,IPR007111; PFAM:PF00004,PF05729 AKAW2_70113S COG:M; EggNog:ENOG410PF7T; InterPro:IPR000845,IPR035994; PFAM:PF01048; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_process: GO:0009116 - nucleoside metabolic process [Evidence IEA] AKAW2_70114S COG:L,T; EggNog:ENOG410PH7Z; InterPro:IPR036155,IPR005101,IPR006050,IPR036134, IPR014729; PFAM:PF03441,PF00875 AKAW2_70115A COG:K; EggNog:ENOG410PNVQ; InterPro:IPR001005,IPR009057,IPR017884; PFAM:PF00249 AKAW2_70116S BUSCO:EOG09263H5H; COG:O; EggNog:ENOG410PHG4; InterPro:IPR029035,IPR002773,IPR036982; PFAM:PF01916; go_process: GO:0008612 - peptidyl-lysine modification to peptidyl-hypusine [Evidence IEA] AKAW2_70117S COG:O; EggNog:ENOG410PH06; InterPro:IPR001841,IPR038765,IPR008974,IPR002083, IPR001394,IPR003409,IPR013083; MEROPS:MER0002475; PFAM:PF13920,PF02493,PF00443; go_function: GO:0004843 - thiol-dependent ubiquitin-specific protease activity [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0016579 - protein deubiquitination [Evidence IEA] AKAW2_70118A COG:A; EggNog:ENOG410PHXV; InterPro:IPR023267,IPR023273,IPR029063,IPR018314, IPR011023,IPR001678,IPR031341; PFAM:PF17125,PF01189; go_function: GO:0003723 - RNA binding [Evidence IEA]; go_function: GO:0008168 - methyltransferase activity [Evidence IEA]; go_function: GO:0008757 - S-adenosylmethionine-dependent methyltransferase activity [Evidence IEA]; go_process: GO:0001510 - RNA methylation [Evidence IEA]; go_process: GO:0006396 - RNA processing [Evidence IEA] AKAW2_70119S COG:S; EggNog:ENOG410PNWE; PFAM:PF17183,PF12754 AKAW2_70120A COG:D; EggNog:ENOG410PJ75; InterPro:IPR013258,IPR036322,IPR015943,IPR019775, IPR001680,IPR017986; PFAM:PF00400,PF08232; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_70121A COG:S; EggNog:ENOG410Q13D; InterPro:IPR013717; PFAM:PF08510; TransMembrane:2 (i197-216o236-259i) AKAW2_70122S COG:S; EggNog:ENOG410PV80; InterPro:IPR003864,IPR027815,IPR032880,IPR022257; PFAM:PF12621,PF14703,PF02714,PF13967; TransMembrane:11 (o50-73i129-152o180-199i428-454o474-502i522-547o567- 596i608-627o633-655i676-701o707-725i); go_component: GO:0016020 - membrane [Evidence IEA] AKAW2_70123A COG:I; EggNog:ENOG410PI64; InterPro:IPR007518,IPR033979; MEROPS:MER1054226; PFAM:PF04424; go_function: GO:0004843 - thiol-dependent ubiquitin-specific protease activity [Evidence IEA]; go_function: GO:1990380 - Lys48-specific deubiquitinase activity [Evidence IEA] AKAW2_70124S BUSCO:EOG09261I0F; COG:J; EggNog:ENOG410PJ0M; InterPro:IPR017423; PFAM:PF04189; go_component: GO:0031515 - tRNA (m1A) methyltransferase complex [Evidence IEA]; go_process: GO:0030488 - tRNA methylation [Evidence IEA] AKAW2_70125A COG:L; EggNog:ENOG410PFQP; InterPro:IPR003959,IPR027417,IPR003593,IPR013748, IPR008921; PFAM:PF13177,PF00004,PF03215,PF08542,PF07728; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA]; go_process: GO:0006260 - DNA replication [Evidence IEA] AKAW2_70126S BUSCO:EOG09264S3E; COG:Z; EggNog:ENOG410PNX6; InterPro:IPR036753,IPR007204; PFAM:PF04062; go_component: GO:0005856 - cytoskeleton [Evidence IEA]; go_component: GO:0005885 - Arp2/3 protein complex [Evidence IEA]; go_process: GO:0030833 - regulation of actin filament polymerization [Evidence IEA]; go_process: GO:0034314 - Arp2/3 complex-mediated actin nucleation [Evidence IEA] AKAW2_70127A COG:G; EggNog:ENOG410Q22C; InterPro:IPR005829,IPR005828,IPR003663,IPR036259, IPR020846; PFAM:PF00083,PF07690; TransMembrane:11 (n8-18c23/24o47-67i79-96o102-127i134-157o169-192i255- 279o291-312i321-339o359-384i396-419o425-444i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_70128S COG:S; EggNog:ENOG410Q2NI; InterPro:IPR041492,IPR003819,IPR023198,IPR036412, IPR042098,IPR023214; PFAM:PF13242,PF12710,PF13419; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_70129A COG:G; EggNog:ENOG410PUHB; InterPro:IPR001312,IPR022673,IPR022672,IPR043129; PFAM:PF00349,PF03727; go_function: GO:0004396 - hexokinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0005536 - glucose binding [Evidence IEA]; go_function: GO:0016773 - phosphotransferase activity, alcohol group as acceptor [Evidence IEA]; go_process: GO:0001678 - cellular glucose homeostasis [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_70130S COG:Q; EggNog:ENOG410PHHZ; InterPro:IPR013154,IPR013149,IPR036291,IPR011032, IPR020843; PFAM:PF00107,PF08240; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_70131S COG:Q; EggNog:ENOG410PVJF; InterPro:IPR002347,IPR036291,IPR020904; PFAM:PF00106,PF13561,PF08659,PF01370; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_70132S COG:G; EggNog:ENOG410QDYM; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i50-66o86-106i118-135o147-167i174-201o207-225i282- 304o316-340i361-381o393-418i430-448o460-481i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_70133A COG:H; EggNog:ENOG410PFX3; InterPro:IPR033749,IPR039702,IPR008949,IPR000092; PFAM:PF00348; go_function: GO:0016765 - transferase activity, transferring alkyl or aryl (other than methyl) groups [Evidence IEA]; go_process: GO:0008299 - isoprenoid biosynthetic process [Evidence IEA] AKAW2_70134A COG:Q; EggNog:ENOG410PVDZ; InterPro:IPR013154,IPR013149,IPR002328,IPR036291, IPR011032,IPR020843; PFAM:PF00107,PF08240,PF16912; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_70135S COG:Q; EggNog:ENOG410PJR0; InterPro:IPR013154,IPR013149,IPR002328,IPR036291, IPR011032,IPR020843; PFAM:PF00107,PF08240; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_70136A COG:C; EggNog:ENOG410PFVQ; InterPro:IPR018170,IPR020471,IPR036812,IPR023210; PFAM:PF00248; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_70137A TransMembrane:2 (o69-88i122-141o) AKAW2_70138S COG:S; EggNog:ENOG410PKYM; InterPro:IPR000560,IPR029033; PFAM:PF00328; SECRETED:SignalP(1-25); TransMembrane:1 (n10-21c25/26o430-453i) AKAW2_70139S COG:S; EggNog:ENOG410PW2Y; InterPro:IPR021838; PFAM:PF11913; SECRETED:SignalP(1-26) AKAW2_70140S COG:O; EggNog:ENOG410PHGD; InterPro:IPR029000,IPR020892,IPR002130; PFAM:PF00160; go_function: GO:0003755 - peptidyl-prolyl cis-trans isomerase activity [Evidence IEA]; go_process: GO:0000413 - protein peptidyl-prolyl isomerization [Evidence IEA]; go_process: GO:0006457 - protein folding [Evidence IEA] AKAW2_70141A COG:K; EggNog:ENOG410PG48; InterPro:IPR000232,IPR027725,IPR036390,IPR036388; PFAM:PF00447; go_function: GO:0003700 - DNA-binding transcription factor activity [Evidence IEA]; go_function: GO:0043565 - sequence-specific DNA binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_70142A SECRETED:SignalP(1-24) AKAW2_70143A COG:S; EggNog:ENOG410PJDA; InterPro:IPR023210,IPR036812,IPR020471; PFAM:PF00248; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_70144S COG:S; EggNog:ENOG410PZVN; SECRETED:SignalP(1-24) AKAW2_70146S COG:A; EggNog:ENOG410PGY9; InterPro:IPR034186,IPR000504,IPR036867,IPR001374, IPR034069,IPR012677,IPR035979; PFAM:PF01424,PF00076; go_function: GO:0003676 - nucleic acid binding [Evidence IEA] AKAW2_70147A COG:B; EggNog:ENOG410PNUW; InterPro:IPR002119,IPR007125,IPR009072,IPR032454; PFAM:PF00125,PF00808,PF16211; go_component: GO:0000786 - nucleosome [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0046982 - protein heterodimerization activity [Evidence IEA] AKAW2_70148S COG:P; EggNog:ENOG410PHVJ; InterPro:IPR012098; PFAM:PF10032; TransMembrane:2 (o29-50i96-114o); go_component: GO:0005783 - endoplasmic reticulum [Evidence IEA]; go_process: GO:0045047 - protein targeting to ER [Evidence IEA] AKAW2_70149S COG:G; EggNog:ENOG410PF9K; InterPro:IPR036291,IPR020831,IPR020830,IPR020828, IPR020829; PFAM:PF00044,PF02800; go_function: GO:0016620 - oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Evidence IEA]; go_function: GO:0051287 - NAD binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_70150S BUSCO:EOG09263E5F; COG:B; EggNog:ENOG410PHNX; InterPro:IPR017321,IPR037138,IPR023696,IPR023801, IPR000286,IPR019154; PFAM:PF09757,PF00850 AKAW2_70151S COG:S; EggNog:ENOG410PR63; InterPro:IPR037176,IPR006771; PFAM:PF04681; SECRETED:SignalP(1-23) AKAW2_70152S COG:O; EggNog:ENOG410PIQE; InterPro:IPR007863,IPR011765,IPR032632,IPR011249; MEROPS:MER0001218; PFAM:PF05193,PF16187,PF00675; go_function: GO:0046872 - metal ion binding [Evidence IEA] AKAW2_70153S COG:A; EggNog:ENOG410PKIN; InterPro:IPR016706; PFAM:PF13869; go_component: GO:0005849 - mRNA cleavage factor complex [Evidence IEA]; go_function: GO:0003729 - mRNA binding [Evidence IEA]; go_process: GO:0006378 - mRNA polyadenylation [Evidence IEA] AKAW2_70154S COG:I; EggNog:ENOG410PKH6; InterPro:IPR002921,IPR029058,IPR005592; PFAM:PF03893,PF01764; SECRETED:SignalP(1-19); go_process: GO:0006629 - lipid metabolic process [Evidence IEA]; go_process: GO:0016042 - lipid catabolic process [Evidence IEA] AKAW2_70155S COG:S; EggNog:ENOG410PIKT; InterPro:IPR021838; PFAM:PF11913; TransMembrane:1 (i20-37o) AKAW2_70156A COG:S; EggNog:ENOG410PT1N; TransMembrane:7 (o17-41i53-71o102-119i131-152o176-196i208-228o248-269i) AKAW2_70157A COG:E; EggNog:ENOG410PIEB; InterPro:IPR002293; SECRETED:SignalP(1-23); TransMembrane:5 (n8-19c23/24o47-67i101-123o129-151i171-193o205-222i); go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_70158A COG:E; EggNog:ENOG410PIEB; TransMembrane:2 (i59-80o92-111i) AKAW2_70159S COG:S; EggNog:ENOG410PR0V; InterPro:IPR011051 AKAW2_70160A COG:G; EggNog:ENOG410Q18W; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690,PF00083; TransMembrane:10 (i161-179o191-210i222-244o256-278i326-349o369-388i400- 421o427-449i461-482o497-517i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_70161S COG:I; EggNog:ENOG410PHDX; InterPro:IPR042098,IPR003819; PFAM:PF02668; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_70163A COG:S; EggNog:ENOG410PQ4F; InterPro:IPR019193; PFAM:PF09814 AKAW2_70164A COG:S; EggNog:ENOG410PNGM; InterPro:IPR027417,IPR007111,IPR036770; PFAM:PF05729 AKAW2_70165A COG:S; EggNog:ENOG410PHW6; InterPro:IPR025337; PFAM:PF14027; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA] AKAW2_70166A COG:E; EggNog:ENOG410PIX6; InterPro:IPR002293,IPR004756; PFAM:PF00324,PF13520; TransMembrane:12 (i25-48o60-85i105-129o149-168i180-203o223-247i259-286o306- 325i362-382o388-410i422-446o458-479i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0006865 - amino acid transport [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_70168A BUSCO:EOG09260VTN; COG:O; EggNog:ENOG410PFF8; InterPro:IPR027417,IPR003593,IPR003960,IPR003959; PFAM:PF00004; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA] AKAW2_70169A CAZy:AA1; COG:Q; EggNog:ENOG410PKIJ; InterPro:IPR008972,IPR011707,IPR011706,IPR033138, IPR002355,IPR001117; PFAM:PF00394,PF07732; go_function: GO:0005507 - copper ion binding [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_70170S COG:K; EggNog:ENOG410PIHM; InterPro:IPR013087 AKAW2_70171A TransMembrane:1 (o38-54i) AKAW2_70172S COG:S; EggNog:ENOG410PRF7; InterPro:IPR015034,IPR023398; PFAM:PF08939 AKAW2_70173A COG:U; EggNog:ENOG410PM0G; InterPro:IPR014812; PFAM:PF08700 AKAW2_70175S COG:S; EggNog:ENOG410PP0C; InterPro:IPR039215,IPR033472,IPR042470,IPR013894; PFAM:PF08585; go_component: GO:0031422 - RecQ family helicase-topoisomerase III complex [Evidence IEA]; go_function: GO:0000166 - nucleotide binding [Evidence IEA] AKAW2_70174A BUSCO:EOG09260779; COG:A; EggNog:ENOG410PHEB; InterPro:IPR011990,IPR019734,IPR039226,IPR040962, IPR013026; PFAM:PF13424,PF13432,PF13176,PF18833,PF13181; go_component: GO:0055087 - Ski complex [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0006401 - RNA catabolic process [Evidence IEA] AKAW2_70176S CAZy:GH5; COG:G; EggNog:ENOG410PGAW; InterPro:IPR017853,IPR001547,IPR041036,IPR018087; PFAM:PF18564; SECRETED:SignalP(1-17); go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA]; go_process: GO:0071704 - organic substance metabolic process [Evidence IEA] AKAW2_70177S COG:U,Y; EggNog:ENOG410PGU3; InterPro:IPR016024,IPR013598,IPR040018,IPR011989; PFAM:PF08389; go_process: GO:0051168 - nuclear export [Evidence IEA] AKAW2_70178A COG:C,D; EggNog:ENOG410PRI3; InterPro:IPR009346; PFAM:PF06212; TransMembrane:1 (o28-47i) AKAW2_70179S BUSCO:EOG09263760; COG:U; EggNog:ENOG410PKY7; InterPro:IPR007356,IPR016653,IPR016009,IPR038459, IPR028564; PFAM:PF01746; go_function: GO:0008168 - methyltransferase activity [Evidence IEA] AKAW2_70180S BUSCO:EOG09260WG2; COG:U; EggNog:ENOG410PIZ4; InterPro:IPR040768,IPR013863,IPR040458,IPR040979; PFAM:PF17747,PF17748,PF08553 AKAW2_70181A BUSCO:EOG092629U5; COG:L; EggNog:ENOG410PJD6; InterPro:IPR006571; PFAM:PF07534 AKAW2_70182A COG:S; EggNog:ENOG410PJU4; InterPro:IPR010497,IPR016292,IPR029058,IPR000639; MEROPS:MER0000432; PFAM:PF06441; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0033961 - cis-stilbene-oxide hydrolase activity [Evidence IEA] AKAW2_70183A COG:Q; EggNog:ENOG410PH86; InterPro:IPR036291,IPR002347; PFAM:PF08659,PF00106,PF13561; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_70184S COG:E; EggNog:ENOG410PHTM; InterPro:IPR036291,IPR003462; PFAM:PF02423 AKAW2_70185A COG:S; EggNog:ENOG410PMHC; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF04082; TransMembrane:2 (o237-258i279-299o); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_70186S COG:E; EggNog:ENOG410Q9UP; InterPro:IPR008794; PFAM:PF05544 AKAW2_70187S COG:E; EggNog:ENOG410PFR0; InterPro:IPR015943,IPR036322; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_70188A BUSCO:EOG09263XN3; COG:O; EggNog:ENOG410PI8S; InterPro:IPR033464,IPR000717,IPR006746; PFAM:PF10075; go_component: GO:0005838 - proteasome regulatory particle [Evidence IEA]; go_process: GO:0006508 - proteolysis [Evidence IEA] AKAW2_70189A COG:S; EggNog:ENOG410PXKN; InterPro:IPR036291,IPR008030; PFAM:PF13460,PF05368,PF01370 AKAW2_70190A COG:O; EggNog:ENOG410PI5I; InterPro:IPR036852,IPR023828,IPR015366,IPR030400; MEROPS:MER0078639; PFAM:PF09286; SECRETED:SignalP(1-19); go_function: GO:0004252 - serine-type endopeptidase activity [Evidence IEA]; go_function: GO:0008236 - serine-type peptidase activity [Evidence IEA]; go_process: GO:0006508 - proteolysis [Evidence IEA] AKAW2_70191A COG:S; EggNog:ENOG410PGZS; InterPro:IPR003480,IPR023213; PFAM:PF02458; antiSMASH:Cluster_7.3; go_function: GO:0016747 - transferase activity, transferring acyl groups other than amino-acyl groups [Evidence IEA] AKAW2_70192A COG:C; EggNog:ENOG410PHVT; InterPro:IPR023210,IPR036812; PFAM:PF00248; SMCOG1039:aldo/keto reductase family oxidoreductase; antiSMASH:Cluster_7.3 AKAW2_70193A COG:C; EggNog:ENOG410PMQH; InterPro:IPR006094,IPR036318,IPR016166,IPR012951; PFAM:PF08031,PF01565; SMCOG1138:FAD linked oxidase domain protein; antiSMASH:Cluster_7.3; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_function: GO:0071949 - FAD binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_70194S InterPro:IPR036864,IPR001138; PFAM:PF00172; antiSMASH:Cluster_7.3; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_70195A COG:C; EggNog:ENOG410PFYI; InterPro:IPR015590,IPR044086,IPR029510,IPR016160, IPR016161,IPR016162,IPR016163; PFAM:PF00171; SMCOG1017:aldehyde dehydrogenase; antiSMASH:Cluster_7.3; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0016620 - oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_70196A COG:Q; EggNog:ENOG410PMTB; InterPro:IPR001128,IPR002401,IPR036396; PFAM:PF00067; SMCOG1034:cytochrome P450; TransMembrane:1 (o28-50i); antiSMASH:Cluster_7.3; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_70197S COG:S; EggNog:ENOG410PZUD; InterPro:IPR036864,IPR001138; PFAM:PF00172; TransMembrane:1 (o330-349i); antiSMASH:Cluster_7.3; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_70198A COG:I; EggNog:ENOG410PJ2Y; InterPro:IPR016036,IPR016035,IPR016039,IPR018201, IPR042104,IPR014030,IPR011032,IPR013968,IPR013154, IPR001227,IPR032821,IPR014031,IPR014043,IPR020807, IPR020843,IPR020841,IPR009081,IPR013149,IPR036736, IPR036291; PFAM:PF16197,PF08659,PF02801,PF00698,PF13602, PF14765,PF00107,PF00106,PF00109,PF08240; SMCOG1093:Beta-ketoacyl synthase; antiSMASH:Cluster_7.3; go_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein] synthase activity [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0016740 - transferase activity [Evidence IEA]; go_function: GO:0016746 - transferase activity, transferring acyl groups [Evidence IEA]; go_process: GO:0006633 - fatty acid biosynthetic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_70199S COG:Q; EggNog:ENOG410PJ06; InterPro:IPR002347,IPR036291,IPR020904; PFAM:PF00106,PF13561,PF08659; SMCOG1001:short-chain dehydrogenase/reductase SDR; antiSMASH:Cluster_7.3; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_70200S COG:Q; EggNog:ENOG410PPEB; InterPro:IPR002347,IPR036291,IPR020904; PFAM:PF00106,PF13561,PF08659; SMCOG1001:short-chain dehydrogenase/reductase SDR; antiSMASH:Cluster_7.3; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_70201S COG:S; EggNog:ENOG410PUX1; InterPro:IPR014710,IPR011051,IPR013096; PFAM:PF07883; antiSMASH:Cluster_7.3 AKAW2_70202A COG:G; EggNog:ENOG410PHC6; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; SMCOG1169:sugar transport protein; TransMembrane:12 (i79-100o120-139i151-169o175-194i206-227o239-258i313- 337o349-371i392-413o419-441i453-475o487-509i); antiSMASH:Cluster_7.3; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_70203A COG:S; EggNog:ENOG410PJQA; InterPro:IPR029069,IPR042171; PFAM:PF13622; antiSMASH:Cluster_7.3 AKAW2_70204S COG:Q; EggNog:ENOG410PK71; InterPro:IPR001128,IPR017972,IPR002401,IPR036396; PFAM:PF00067; SMCOG1034:cytochrome P450; antiSMASH:Cluster_7.3; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_70205S COG:Q; EggNog:ENOG410PP6F; InterPro:IPR026992,IPR027443,IPR005123; PFAM:PF03171,PF14226; antiSMASH:Cluster_7.3; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_70206S COG:Q; EggNog:ENOG410PNW3; InterPro:IPR036291,IPR002347; PFAM:PF08659,PF00106,PF13561; SMCOG1001:short-chain dehydrogenase/reductase SDR; antiSMASH:Cluster_7.3; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_70207S COG:S; EggNog:ENOG410PII7; InterPro:IPR016461,IPR036390,IPR036388; antiSMASH:Cluster_7.3; go_function: GO:0008168 - methyltransferase activity [Evidence IEA] AKAW2_70208S COG:S; EggNog:ENOG410PII7; InterPro:IPR001077,IPR016461,IPR029063; PFAM:PF13649,PF08241,PF00891; SMCOG1042:O-methyltransferase; antiSMASH:Cluster_7.3; go_function: GO:0008168 - methyltransferase activity [Evidence IEA]; go_function: GO:0008171 - O-methyltransferase activity [Evidence IEA] AKAW2_70209A COG:S; EggNog:ENOG410PKB0; InterPro:IPR007325,IPR037175; PFAM:PF04199; go_function: GO:0004061 - arylformamidase activity [Evidence IEA]; go_process: GO:0019441 - tryptophan catabolic process to kynurenine [Evidence IEA] AKAW2_70210S COG:Q; EggNog:ENOG410PIWX; InterPro:IPR001128,IPR002403,IPR017972,IPR036396; PFAM:PF00067; TransMembrane:4 (i25-48o60-77i236-256o311-331i); go_function: GO:0004497 - monooxygenase activity [Evidence IEA]; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_70211S COG:S; EggNog:ENOG410PX36 AKAW2_70212A COG:S; EggNog:ENOG410PXQZ; InterPro:IPR006603; PFAM:PF04193; TransMembrane:7 (o6-24i36-60o80-103i115-136o156-176i197-217o237-258i) AKAW2_70213S COG:S; EggNog:ENOG410Q2NB AKAW2_70214S COG:O; EggNog:ENOG410PK6J; InterPro:IPR038397,IPR017901,IPR006599,IPR016098, IPR012945,IPR027684; PFAM:PF07986; go_process: GO:0000902 - cell morphogenesis [Evidence IEA]; go_process: GO:0007023 - post-chaperonin tubulin folding pathway [Evidence IEA] AKAW2_70215A COG:S; EggNog:ENOG410PHFS AKAW2_70216A COG:S; EggNog:ENOG410Q2BA AKAW2_70217S COG:U; EggNog:ENOG410PH6I; InterPro:IPR001680,IPR036322,IPR019775,IPR015943, IPR010714,IPR016391,IPR006692,IPR020472,IPR011044, IPR017986; PFAM:PF06957,PF04053; go_component: GO:0030117 - membrane coat [Evidence IEA]; go_component: GO:0030126 - COPI vesicle coat [Evidence IEA]; go_function: GO:0005198 - structural molecule activity [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0006886 - intracellular protein transport [Evidence IEA]; go_process: GO:0016192 - vesicle-mediated transport [Evidence IEA] AKAW2_70218A COG:O; EggNog:ENOG410PP4X; InterPro:IPR036774,IPR017905,IPR039799; PFAM:PF04777; go_function: GO:0016971 - flavin-linked sulfhydryl oxidase activity [Evidence IEA]; go_function: GO:0016972 - thiol oxidase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_70219S COG:K; EggNog:ENOG410PR9K; InterPro:IPR037647 AKAW2_70220S COG:U; EggNog:ENOG410PFBW; InterPro:IPR016024,IPR011989,IPR026739,IPR016342, IPR002553; PFAM:PF01602,PF12717; go_component: GO:0030117 - membrane coat [Evidence IEA]; go_function: GO:0030276 - clathrin binding [Evidence IEA]; go_process: GO:0006886 - intracellular protein transport [Evidence IEA]; go_process: GO:0015031 - protein transport [Evidence IEA]; go_process: GO:0016192 - vesicle-mediated transport [Evidence IEA] AKAW2_70221S BUSCO:EOG09260XOG; COG:E; EggNog:ENOG410PFFQ; InterPro:IPR002028,IPR011060,IPR023026,IPR001926, IPR036052,IPR013785,IPR018204,IPR006654,IPR006653; PFAM:PF00291,PF00290; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0004834 - tryptophan synthase activity [Evidence IEA]; go_process: GO:0000162 - tryptophan biosynthetic process [Evidence IEA]; go_process: GO:0006568 - tryptophan metabolic process [Evidence IEA] AKAW2_70222S COG:Q; EggNog:ENOG410PJ3Q; InterPro:IPR013154,IPR013149,IPR002328,IPR036291, IPR011032; PFAM:PF00107,PF08240,PF13602; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_70223S BUSCO:EOG09261B6Y; COG:E; EggNog:ENOG410PGKC; InterPro:IPR029144,IPR004450,IPR001926,IPR036052, IPR000634,IPR037158; PFAM:PF00291,PF14821; go_function: GO:0030170 - pyridoxal phosphate binding [Evidence IEA]; go_process: GO:0006520 - cellular amino acid metabolic process [Evidence IEA] AKAW2_70224A SECRETED:SignalP(1-17) AKAW2_70225S BUSCO:EOG09261ZI1; COG:L; EggNog:ENOG410PG27; InterPro:IPR014052,IPR002755; PFAM:PF01896; go_function: GO:0003896 - DNA primase activity [Evidence IEA]; go_process: GO:0006269 - DNA replication, synthesis of RNA primer [Evidence IEA] AKAW2_70226S COG:V; EggNog:ENOG410PWKF; InterPro:IPR001466,IPR012338,IPR021860; MEROPS:MER0026262; PFAM:PF11954,PF00144 AKAW2_70227A BUSCO:EOG0926577T; COG:C; EggNog:ENOG410PNBT; InterPro:IPR003428,IPR036561; PFAM:PF02330; go_component: GO:0005759 - mitochondrial matrix [Evidence IEA] AKAW2_70228A COG:S; EggNog:ENOG410PRAY; InterPro:IPR021346,IPR038356; PFAM:PF11176 AKAW2_70229S BUSCO:EOG09262A65; COG:L; EggNog:ENOG410PFQY; InterPro:IPR006086,IPR006084,IPR006085,IPR019974, IPR029060,IPR036279,IPR008918,IPR037315,IPR032641; PFAM:PF00867,PF00752; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0004518 - nuclease activity [Evidence IEA]; go_function: GO:0016788 - hydrolase activity, acting on ester bonds [Evidence IEA]; go_function: GO:0035312 - 5'-3' exodeoxyribonuclease activity [Evidence IEA]; go_process: GO:0006281 - DNA repair [Evidence IEA] AKAW2_70230S COG:S; EggNog:ENOG410PM0A; InterPro:IPR016509,IPR033481; PFAM:PF12351; TransMembrane:4 (o20-39i140-163o183-204i234-257o); go_component: GO:0016020 - membrane [Evidence IEA]; go_process: GO:0000753 - cell morphogenesis involved in conjugation with cellular fusion [Evidence IEA]; go_process: GO:0032220 - plasma membrane fusion involved in cytogamy [Evidence IEA] AKAW2_70231A COG:U; EggNog:ENOG410QDYJ; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i118-138o158-177i189-207o213-235i247-269o281-306i354- 373o393-413i434-453o459-484i504-520o526-548i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_70232S COG:S; EggNog:ENOG410PXA7; InterPro:IPR027417,IPR003959; PFAM:PF00004; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA] AKAW2_70233A COG:S; EggNog:ENOG410PGXH; InterPro:IPR018812; PFAM:PF10307 AKAW2_70234S COG:O; EggNog:ENOG410PN69; InterPro:IPR001841,IPR013083; PFAM:PF00097,PF13920,PF13639 AKAW2_70235A COG:L; EggNog:ENOG410PKFZ; InterPro:IPR040203,IPR021110; PFAM:PF11719; go_process: GO:0006270 - DNA replication initiation [Evidence IEA] AKAW2_70236A COG:O; EggNog:ENOG410PIKD; InterPro:IPR036249,IPR009737; PFAM:PF06999 AKAW2_70237S COG:S; EggNog:ENOG410PKZB; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; TransMembrane:1 (o320-340i); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_70238S CAZy:GH43; COG:G; EggNog:ENOG410PUHR; InterPro:IPR016840,IPR023296,IPR006710; PFAM:PF04616; SECRETED:SignalP(1-18); TransMembrane:1 (n2-13c18/19o362-379i); go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_function: GO:0046558 - arabinan endo-1,5-alpha-L-arabinosidase activity [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_70239A COG:Q; EggNog:ENOG410PPIZ; InterPro:IPR002347,IPR036291,IPR020904; PFAM:PF00106,PF13561,PF08659; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_70240A COG:T; EggNog:ENOG410PV4K; InterPro:IPR000719,IPR011009,IPR008271; PFAM:PF00069; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_70241S COG:S; EggNog:ENOG410Q0BK AKAW2_70242A COG:H; EggNog:ENOG410PM0Y; InterPro:IPR039653,IPR000537; PFAM:PF01040; TransMembrane:8 (o61-82i102-122o128-151i158-176o188-209i230-250o256- 274i295-313o); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0016765 - transferase activity, transferring alkyl or aryl (other than methyl) groups [Evidence IEA] AKAW2_70243A CAZy:GH95; COG:G; EggNog:ENOG410PJKJ; InterPro:IPR027414,IPR016518,IPR008928,IPR012341; PFAM:PF14498; SECRETED:SignalP(1-20); go_function: GO:0004560 - alpha-L-fucosidase activity [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_70244A COG:Q; EggNog:ENOG410PHSG; InterPro:IPR020946,IPR036188,IPR000960; PFAM:PF13450; go_function: GO:0004499 - N,N-dimethylaniline monooxygenase activity [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_function: GO:0050661 - NADP binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_70245S SECRETED:SignalP(1-17) AKAW2_70246A COG:Q; EggNog:ENOG410QDBT; InterPro:IPR002401,IPR001433,IPR036396,IPR017927, IPR003097,IPR017972,IPR023173,IPR029039,IPR001128, IPR008254,IPR017938,IPR039261,IPR023206; PFAM:PF00175,PF00067,PF00258,PF00667; go_function: GO:0003958 - NADPH-hemoprotein reductase activity [Evidence IEA]; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0010181 - FMN binding [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_function: GO:0070330 - aromatase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_70247A CAZy:GH16; COG:G; EggNog:ENOG410PJVM; InterPro:IPR000757,IPR013320; PFAM:PF00722; SECRETED:SignalP(1-19); TransMembrane:1 (n3-14c19/20o296-318i); go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_70248A COG:S; EggNog:ENOG410Q0NI AKAW2_70249S COG:S; EggNog:ENOG410PMCH AKAW2_70250S COG:S; EggNog:ENOG410PHUH; InterPro:IPR031100,IPR005269; PFAM:PF03641 AKAW2_70251A COG:F; EggNog:ENOG410PJ4E; InterPro:IPR001365,IPR006330,IPR032466,IPR006650; PFAM:PF00962; TransMembrane:1 (o20-37i); go_function: GO:0019239 - deaminase activity [Evidence IEA]; go_process: GO:0009168 - purine ribonucleoside monophosphate biosynthetic process [Evidence IEA] AKAW2_70252A CAZy:GH92; COG:L; EggNog:ENOG410PI20; InterPro:IPR041371,IPR014718,IPR012939,IPR005887; PFAM:PF17678,PF07971; SECRETED:SignalP(1-26); go_function: GO:0030246 - carbohydrate binding [Evidence IEA] AKAW2_70253S COG:S; EggNog:ENOG410PRK7; InterPro:IPR036236,IPR036864,IPR007219,IPR013087, IPR001138; PFAM:PF00172,PF04082; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_70254A COG:I; EggNog:ENOG410Q2DU; InterPro:IPR006694; PFAM:PF04116; TransMembrane:3 (o69-93i114-134o154-172i); go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0008610 - lipid biosynthetic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_70255S COG:J; EggNog:ENOG410PMBK; InterPro:IPR016024,IPR016020,IPR036388,IPR009374, IPR036390,IPR033464,IPR000717; PFAM:PF10075; go_component: GO:0005737 - cytoplasm [Evidence IEA]; go_component: GO:0005852 - eukaryotic translation initiation factor 3 complex [Evidence IEA]; go_function: GO:0003743 - translation initiation factor activity [Evidence IEA]; go_function: GO:0043022 - ribosome binding [Evidence IEA]; go_process: GO:0006446 - regulation of translational initiation [Evidence IEA] AKAW2_70256A BUSCO:EOG09263F11; COG:S; EggNog:ENOG410PGR8; InterPro:IPR007320; PFAM:PF04194; go_component: GO:0005737 - cytoplasm [Evidence IEA] AKAW2_70257S COG:O; EggNog:ENOG410PGAB; InterPro:IPR010795,IPR017046,IPR036188; PFAM:PF07156; TransMembrane:1 (i12-31o); go_function: GO:0001735 - prenylcysteine oxidase activity [Evidence IEA]; go_function: GO:0016670 - oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor [Evidence IEA]; go_process: GO:0030328 - prenylcysteine catabolic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_70258A COG:E; EggNog:ENOG410PFHX; InterPro:IPR019798,IPR039429,IPR001085,IPR015424, IPR015421,IPR015422; PFAM:PF00464,PF00155; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0004372 - glycine hydroxymethyltransferase activity [Evidence IEA]; go_function: GO:0030170 - pyridoxal phosphate binding [Evidence IEA]; go_process: GO:0019264 - glycine biosynthetic process from serine [Evidence IEA]; go_process: GO:0035999 - tetrahydrofolate interconversion [Evidence IEA] AKAW2_70260A COG:S; EggNog:ENOG410PTYG; InterPro:IPR011425; PFAM:PF07544; go_component: GO:0016592 - mediator complex [Evidence IEA]; go_function: GO:0003712 - transcription coregulator activity [Evidence IEA]; go_process: GO:0006357 - regulation of transcription by RNA polymerase II [Evidence IEA] AKAW2_70259S COG:G; EggNog:ENOG410PHC1; InterPro:IPR011258,IPR036646,IPR017850,IPR005995, IPR006124; PFAM:PF06415,PF01676; go_component: GO:0005737 - cytoplasm [Evidence IEA]; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0004619 - phosphoglycerate mutase activity [Evidence IEA]; go_function: GO:0030145 - manganese ion binding [Evidence IEA]; go_function: GO:0046872 - metal ion binding [Evidence IEA]; go_process: GO:0006007 - glucose catabolic process [Evidence IEA] AKAW2_70262A BUSCO:EOG09265E8A; COG:O; EggNog:ENOG410PQV2; InterPro:IPR002777,IPR009053; PFAM:PF01920; go_component: GO:0016272 - prefoldin complex [Evidence IEA]; go_function: GO:0051082 - unfolded protein binding [Evidence IEA]; go_process: GO:0006457 - protein folding [Evidence IEA] AKAW2_70263S COG:O; EggNog:ENOG410PG4M; InterPro:IPR007330,IPR003959,IPR003960,IPR027417, IPR003593,IPR036181,IPR015415; PFAM:PF09336,PF00004,PF04212; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA] AKAW2_70264A COG:S; EggNog:ENOG410PKZY; InterPro:IPR012943,IPR019528; PFAM:PF07989,PF10495; go_component: GO:0005815 - microtubule organizing center [Evidence IEA] AKAW2_70265S COG:K; EggNog:ENOG410PFBE; InterPro:IPR010770; PFAM:PF07093 AKAW2_70266S BUSCO:EOG09263ZSC; COG:S; EggNog:ENOG410PN75; InterPro:IPR023473,IPR036071,IPR027485,IPR002733; PFAM:PF01871 AKAW2_70267A COG:T; EggNog:ENOG410PFTR; InterPro:IPR000719,IPR011009; TransMembrane:1 (o35-52i); go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_70268A BUSCO:EOG092600W1; COG:L; EggNog:ENOG410PGZD; InterPro:IPR012337,IPR006172,IPR029703,IPR036397, IPR013697,IPR043502,IPR042087,IPR006133,IPR006134; PFAM:PF03104,PF10108,PF08490,PF00136; go_component: GO:0005634 - nucleus [Evidence IEA]; go_component: GO:0008622 - epsilon DNA polymerase complex [Evidence IEA]; go_function: GO:0000166 - nucleotide binding [Evidence IEA]; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0003887 - DNA-directed DNA polymerase activity [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006260 - DNA replication [Evidence IEA]; go_process: GO:0006281 - DNA repair [Evidence IEA] AKAW2_70269S COG:S; EggNog:ENOG410PSGF; InterPro:IPR022533; PFAM:PF12597; TransMembrane:2 (i92-110o116-134i); go_component: GO:0005743 - mitochondrial inner membrane [Evidence IEA]; go_process: GO:0033617 - mitochondrial cytochrome c oxidase assembly [Evidence IEA] AKAW2_70270A COG:S; EggNog:ENOG410PS5P AKAW2_70271A COG:A; EggNog:ENOG410PGNS; InterPro:IPR012976,IPR012974,IPR002687,IPR036070, IPR029012,IPR042239; PFAM:PF08156,PF01798 AKAW2_70272S BUSCO:EOG09262516; COG:O; EggNog:ENOG410PHIM; InterPro:IPR002423,IPR012722,IPR027410,IPR027413, IPR017998,IPR002194,IPR027409; PFAM:PF00118; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0051082 - unfolded protein binding [Evidence IEA]; go_process: GO:0006457 - protein folding [Evidence IEA] AKAW2_70273A COG:B; EggNog:ENOG410PNE7; InterPro:IPR036388,IPR016181,IPR040706,IPR002717; PFAM:PF01853,PF17772; go_function: GO:0004402 - histone acetyltransferase activity [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA]; go_process: GO:0016573 - histone acetylation [Evidence IEA] AKAW2_70274S COG:A; EggNog:ENOG410PX55; InterPro:IPR000504,IPR012677,IPR035979; PFAM:PF00076; go_function: GO:0003676 - nucleic acid binding [Evidence IEA] AKAW2_70275S COG:J; EggNog:ENOG410PI3Y; InterPro:IPR006195,IPR002312,IPR012340,IPR004364, IPR004522; PFAM:PF00152; go_function: GO:0000166 - nucleotide binding [Evidence IEA]; go_function: GO:0004812 - aminoacyl-tRNA ligase activity [Evidence IEA]; go_function: GO:0004816 - asparagine-tRNA ligase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006418 - tRNA aminoacylation for protein translation [Evidence IEA]; go_process: GO:0006421 - asparaginyl-tRNA aminoacylation [Evidence IEA] AKAW2_70276A COG:S; EggNog:ENOG410PIK1; InterPro:IPR023213,IPR003480; PFAM:PF02458; go_function: GO:0016747 - transferase activity, transferring acyl groups other than amino-acyl groups [Evidence IEA] AKAW2_70277S COG:G,T; EggNog:ENOG410PVZF; InterPro:IPR018608; PFAM:PF09729 AKAW2_70280S COG:K; EggNog:ENOG410PHUC; InterPro:IPR036864,IPR021858,IPR001138; PFAM:PF00172,PF11951; TransMembrane:1 (o584-603i); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_70281A COG:E; EggNog:ENOG410PFIU; InterPro:IPR002293,IPR004840; PFAM:PF13520,PF00324; TransMembrane:11 (o31-54i61-85o159-176i183-205o225-244i265-292o319-338i371- 389o395-413i434-455o467-486i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0006865 - amino acid transport [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_70283S COG:U; EggNog:ENOG410PHK7; InterPro:IPR007123,IPR036180,IPR012990,IPR036465, IPR006895,IPR006896,IPR036175,IPR036174,IPR006900, IPR029006; PFAM:PF04810,PF08033,PF04815,PF00626,PF04811; go_component: GO:0030127 - COPII vesicle coat [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006886 - intracellular protein transport [Evidence IEA]; go_process: GO:0006888 - endoplasmic reticulum to Golgi vesicle-mediated transport [Evidence IEA] AKAW2_70284S COG:S; EggNog:ENOG410QEFP; SECRETED:SignalP(1-17) AKAW2_70285A BUSCO:EOG09260MBW; COG:A; EggNog:ENOG410PHC8; InterPro:IPR036866,IPR027075,IPR025069,IPR011108, IPR001279,IPR035639,IPR022712; PFAM:PF13299,PF10996,PF16661,PF07521; go_component: GO:0005847 - mRNA cleavage and polyadenylation specificity factor complex [Evidence IEA]; go_process: GO:0006378 - mRNA polyadenylation [Evidence IEA]; go_process: GO:0006379 - mRNA cleavage [Evidence IEA] AKAW2_70287A BUSCO:EOG092605KN; COG:T; EggNog:ENOG410PG2W; InterPro:IPR027317,IPR019402,IPR036691; PFAM:PF10277; TransMembrane:18 (o37-58i70-87o99-119i131-148o168-191i238-259o265-283i295- 311o317-337i349-370o382-398i419-436o456-478i485-504o510- 529i541-560o572-590i611-631o) AKAW2_70288S COG:A; EggNog:ENOG410PJM9; InterPro:IPR013949,IPR003107,IPR011990; PFAM:PF08640; go_function: GO:0005515 - protein binding [Evidence IEA]; go_function: GO:0030515 - snoRNA binding [Evidence IEA]; go_process: GO:0000462 - maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [Evidence IEA]; go_process: GO:0006396 - RNA processing [Evidence IEA] AKAW2_70289A BUSCO:EOG09264PDD; COG:J; EggNog:ENOG410PQCW; InterPro:IPR000352; PFAM:PF00472; go_function: GO:0003747 - translation release factor activity [Evidence IEA]; go_process: GO:0006415 - translational termination [Evidence IEA] AKAW2_70290S COG:S; EggNog:ENOG410QDTA; InterPro:IPR000504,IPR012677,IPR035979; PFAM:PF00076; go_function: GO:0003676 - nucleic acid binding [Evidence IEA] AKAW2_70291A BUSCO:EOG09265GYD; COG:S; EggNog:ENOG410PRWH; InterPro:IPR003213,IPR036549; PFAM:PF02297; go_component: GO:0005739 - mitochondrion [Evidence IEA]; go_component: GO:0045277 - respiratory chain complex IV [Evidence IEA] AKAW2_70292S COG:U; EggNog:ENOG410PP55; InterPro:IPR019185; PFAM:PF09801; TransMembrane:4 (i21-48o68-92i99-117o123-144i) AKAW2_70293S COG:T,Z; EggNog:ENOG410PJ5R; InterPro:IPR036409,IPR001303; PFAM:PF00596 AKAW2_70294S COG:J; EggNog:ENOG410PGUF; InterPro:IPR019465; PFAM:PF10392; go_component: GO:0017119 - Golgi transport complex [Evidence IEA]; go_process: GO:0006891 - intra-Golgi vesicle-mediated transport [Evidence IEA] AKAW2_70296S COG:K; EggNog:ENOG410PGNP; InterPro:IPR036236,IPR013087; PFAM:PF00096 AKAW2_70297S COG:S; EggNog:ENOG410PR1H AKAW2_70298S COG:S; EggNog:ENOG410PQEH; InterPro:IPR032054; PFAM:PF16679 AKAW2_70299S BUSCO:EOG09260EPQ; COG:L; EggNog:ENOG410PF86; InterPro:IPR027417,IPR036678,IPR036187,IPR007696, IPR011184,IPR016151,IPR032642,IPR000432,IPR007695, IPR007861,IPR007860; PFAM:PF05188,PF05190,PF05192,PF00488,PF01624; go_component: GO:0032300 - mismatch repair complex [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0030983 - mismatched DNA binding [Evidence IEA]; go_process: GO:0006298 - mismatch repair [Evidence IEA] AKAW2_70300S COG:S; EggNog:ENOG410QA1C; TransMembrane:1 (n4-14c19/20o43-65i) AKAW2_70301S COG:G; EggNog:ENOG410PFBS; InterPro:IPR007720; PFAM:PF05024; TransMembrane:9 (i236-256o262-282i347-365o371-395i407-429o435-455i467- 492o512-537i549-568o); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0017176 - phosphatidylinositol N-acetylglucosaminyltransferase activity [Evidence IEA]; go_process: GO:0006506 - GPI anchor biosynthetic process [Evidence IEA] AKAW2_70302A COG:S; EggNog:ENOG410PSKT; InterPro:IPR007918; PFAM:PF05254 AKAW2_70303S BUSCO:EOG0926158Y; COG:J; EggNog:ENOG410PGUF; InterPro:IPR012337,IPR002562,IPR010997,IPR002121, IPR012588; PFAM:PF08066,PF01612,PF00570; go_component: GO:0000176 - nuclear exosome (RNase complex) [Evidence IEA]; go_function: GO:0000166 - nucleotide binding [Evidence IEA]; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0008408 - 3'-5' exonuclease activity [Evidence IEA]; go_process: GO:0006139 - nucleobase-containing compound metabolic process [Evidence IEA]; go_process: GO:0006396 - RNA processing [Evidence IEA]; go_process: GO:0044237 - cellular metabolic process [Evidence IEA] AKAW2_70304A COG:S; EggNog:ENOG410PWMW; InterPro:IPR007482; PFAM:PF04387; TransMembrane:6 (i12-33o45-62i69-90o102-121i133-154o166-185i) AKAW2_70306S COG:T; EggNog:ENOG410QD7G; InterPro:IPR001936,IPR000593,IPR023152,IPR008936; PFAM:PF03836,PF00616; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0007165 - signal transduction [Evidence IEA]; go_process: GO:0043087 - regulation of GTPase activity [Evidence IEA] AKAW2_70307S COG:I; EggNog:ENOG410PG4Q; InterPro:IPR011074,IPR036865,IPR036273,IPR001251; PFAM:PF00650,PF03765 AKAW2_70308A COG:S; EggNog:ENOG410PSR7; InterPro:IPR013950; PFAM:PF08641; go_component: GO:0000776 - kinetochore [Evidence IEA]; go_process: GO:0000070 - mitotic sister chromatid segregation [Evidence IEA] AKAW2_70309S COG:S; EggNog:ENOG410PIJF; InterPro:IPR006614; go_component: GO:0016021 - integral component of membrane [Evidence IEA] AKAW2_70310S COG:S; EggNog:ENOG410PWW2; InterPro:IPR011990; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_70311A BUSCO:EOG092645LS; COG:S; EggNog:ENOG410PNPA; InterPro:IPR016181,IPR000182; PFAM:PF13508,PF13673,PF13302,PF08445,PF00583; go_function: GO:0008080 - N-acetyltransferase activity [Evidence IEA] AKAW2_70312S COG:I; EggNog:ENOG410PGW1; InterPro:IPR003386,IPR029058; PFAM:PF02450; TransMembrane:1 (i52-70o); go_function: GO:0008374 - O-acyltransferase activity [Evidence IEA]; go_process: GO:0006629 - lipid metabolic process [Evidence IEA] AKAW2_70313A COG:I; EggNog:ENOG410PJZF; InterPro:IPR026841,IPR000326; PFAM:PF01569,PF14378; TransMembrane:8 (i77-96o102-120i127-144o185-207i214-233o281-301i308- 324o330-348i) AKAW2_70314A COG:S; EggNog:ENOG410PHKX; InterPro:IPR008217; PFAM:PF01988; TransMembrane:5 (i64-82o94-116i193-217o229-249i261-283o); go_function: GO:0005384 - manganese ion transmembrane transporter activity [Evidence IEA]; go_process: GO:0030026 - cellular manganese ion homeostasis [Evidence IEA] AKAW2_70315S COG:I; EggNog:ENOG410Q1PH; InterPro:IPR017850,IPR007312; PFAM:PF04185; SECRETED:SignalP(1-17); go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0016788 - hydrolase activity, acting on ester bonds [Evidence IEA] AKAW2_70316A COG:S; EggNog:ENOG410PSJE; TransMembrane:1 (o6-28i) AKAW2_70317A COG:S; EggNog:ENOG410PXEX; InterPro:IPR013783,IPR032640,IPR014756 AKAW2_70319S COG:T; EggNog:ENOG410PGW3; InterPro:IPR014710,IPR000595,IPR018488,IPR018490; PFAM:PF00027 AKAW2_70320A COG:S; EggNog:ENOG410PNNI; InterPro:IPR006620,IPR005123; PFAM:PF13640; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0031418 - L-ascorbic acid binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_70321S COG:K; EggNog:ENOG410PQXQ; InterPro:IPR036388,IPR001766,IPR036390,IPR008984, IPR000253; PFAM:PF00250,PF00498; go_function: GO:0003700 - DNA-binding transcription factor activity [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_function: GO:0043565 - sequence-specific DNA binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_70323S COG:S; EggNog:ENOG410PPQ6; InterPro:IPR013922,IPR036915; PFAM:PF08613,PF00134; TransMembrane:1 (o196-219i); go_function: GO:0019901 - protein kinase binding [Evidence IEA]; go_process: GO:0000079 - regulation of cyclin-dependent protein serine/threonine kinase activity [Evidence IEA] AKAW2_70324A COG:G; EggNog:ENOG410PH33; InterPro:IPR013078,IPR029033; PFAM:PF00300 AKAW2_70325S COG:U; EggNog:ENOG410PH2M; InterPro:IPR007255; PFAM:PF04124; go_component: GO:0017119 - Golgi transport complex [Evidence IEA] AKAW2_70326S COG:S; EggNog:ENOG410PRS5; InterPro:IPR019194; PFAM:PF09816 AKAW2_70327S COG:D; EggNog:ENOG410PMSI; InterPro:IPR006671,IPR036915,IPR013763,IPR043198; PFAM:PF00134; go_function: GO:0016538 - cyclin-dependent protein serine/threonine kinase regulator activity [Evidence IEA]; go_process: GO:0006357 - regulation of transcription by RNA polymerase II [Evidence IEA] AKAW2_70328S COG:S; EggNog:ENOG410PMYC; InterPro:IPR036864,IPR001138; PFAM:PF00172; TransMembrane:1 (o347-366i); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_70329A COG:S; EggNog:ENOG410PKNA; InterPro:IPR018823,IPR018820; PFAM:PF13515,PF10337,PF10334; TransMembrane:13 (i45-62o68-83i90-112o164-182i191-211o223-242i603-620o626- 647i654-675o681-700i707-725o745-765i948-969o) AKAW2_70330A COG:T; EggNog:ENOG410PH4B; InterPro:IPR008271,IPR000961,IPR000719,IPR011009; PFAM:PF07714,PF00069; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0004674 - protein serine/threonine kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_70331A COG:H; EggNog:ENOG410Q4KA; InterPro:IPR043133,IPR006157; PFAM:PF02152; go_function: GO:0004150 - dihydroneopterin aldolase activity [Evidence IEA]; go_process: GO:0006760 - folic acid-containing compound metabolic process [Evidence IEA] AKAW2_70332A COG:C; EggNog:ENOG410PFF4; InterPro:IPR000504,IPR012677,IPR035979; PFAM:PF00076; go_function: GO:0003676 - nucleic acid binding [Evidence IEA] AKAW2_70334S BUSCO:EOG092619EA; COG:C; EggNog:ENOG410PFF4; InterPro:IPR040156,IPR036188,IPR017896; PFAM:PF13450,PF05187; go_function: GO:0004174 - electron-transferring-flavoprotein dehydrogenase activity [Evidence IEA]; go_process: GO:0022900 - electron transport chain [Evidence IEA] AKAW2_70335S TransMembrane:1 (o200-219i) AKAW2_70336S BUSCO:EOG09264HTG; COG:K; EggNog:ENOG410PFIH; InterPro:IPR030491,IPR000814,IPR033710,IPR012295; PFAM:PF00352; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_process: GO:0006352 - DNA-templated transcription, initiation [Evidence IEA] AKAW2_70337A COG:E; EggNog:ENOG410PKH1; InterPro:IPR006076,IPR036188; PFAM:PF13454,PF01266; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_70338S COG:Q; EggNog:ENOG410PGYN; InterPro:IPR027034,IPR029063; PFAM:PF13649,PF13489,PF08242,PF08241; TransMembrane:1 (o64-84i) AKAW2_70339S COG:S; EggNog:ENOG410PMW9 AKAW2_70340S COG:K; EggNog:ENOG410PKDN; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_70341S COG:S; EggNog:ENOG410PVIT AKAW2_70342A BUSCO:EOG092619RJ; COG:D; EggNog:ENOG410PG2Z; InterPro:IPR005550,IPR038273; PFAM:PF03801; go_component: GO:0031262 - Ndc80 complex [Evidence IEA]; go_process: GO:0051315 - attachment of mitotic spindle microtubules to kinetochore [Evidence IEA] AKAW2_70343S BUSCO:EOG092643S6; COG:U; EggNog:ENOG410PFAY; InterPro:IPR006785,IPR025655,IPR036388; PFAM:PF04695; go_component: GO:0005778 - peroxisomal membrane [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0016560 - protein import into peroxisome matrix, docking [Evidence IEA] AKAW2_70344S COG:S; EggNog:ENOG410PNSG AKAW2_70345S COG:S; EggNog:ENOG410PKPP; InterPro:IPR011009,IPR002575; PFAM:PF01636 AKAW2_70346A COG:O; EggNog:ENOG410PGIB; InterPro:IPR027746,IPR036523,IPR002828,IPR004344; PFAM:PF01975,PF03133; go_function: GO:0016787 - hydrolase activity [Evidence IEA]; go_process: GO:0006464 - cellular protein modification process [Evidence IEA] AKAW2_70347A COG:S; EggNog:ENOG410PQV6; InterPro:IPR009617; PFAM:PF06775; TransMembrane:1 (i191-216o); go_process: GO:0019915 - lipid storage [Evidence IEA] AKAW2_70348A BUSCO:EOG092600SK; COG:K; EggNog:ENOG410PIRN; InterPro:IPR040398,IPR016021,IPR007196,IPR038535, IPR032194,IPR032193,IPR032191,IPR024557; PFAM:PF12842,PF04054,PF16415,PF16417,PF16418; go_component: GO:0030015 - CCR4-NOT core complex [Evidence IEA]; go_process: GO:0006417 - regulation of translation [Evidence IEA] AKAW2_70349S COG:D; EggNog:ENOG410QEC6; InterPro:IPR001060,IPR027267,IPR036028,IPR031160, IPR001452; PFAM:PF14604,PF00018,PF00611,PF07653; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_70350A COG:S; EggNog:ENOG410PPQQ; TransMembrane:3 (o98-115i127-145o151-169i) AKAW2_70352A COG:S; EggNog:ENOG410PSGQ; InterPro:IPR013960; PFAM:PF08651; go_component: GO:0042729 - DASH complex [Evidence IEA]; go_component: GO:0072686 - mitotic spindle [Evidence IEA]; go_process: GO:0000278 - mitotic cell cycle [Evidence IEA] AKAW2_70353S COG:S; EggNog:ENOG410PU04 AKAW2_70354A BUSCO:EOG092618UZ; COG:D; EggNog:ENOG410PGEA; InterPro:IPR040184,IPR015408; PFAM:PF09329; go_component: GO:0005634 - nucleus [Evidence IEA]; go_function: GO:0003690 - double-stranded DNA binding [Evidence IEA]; go_function: GO:0003697 - single-stranded DNA binding [Evidence IEA]; go_process: GO:0006260 - DNA replication [Evidence IEA]; go_process: GO:0006270 - DNA replication initiation [Evidence IEA] AKAW2_70355S COG:S; EggNog:ENOG410PN3V; InterPro:IPR019024,IPR041195,IPR040456; PFAM:PF17745,PF09468; TransMembrane:1 (i117-135o); go_component: GO:0032299 - ribonuclease H2 complex [Evidence IEA] AKAW2_70356A COG:G; EggNog:ENOG410PGJ4; InterPro:IPR013750,IPR019539,IPR006204,IPR006206, IPR036554,IPR000705,IPR019741,IPR020568,IPR014721; PFAM:PF10509,PF08544,PF00288; go_component: GO:0005737 - cytoplasm [Evidence IEA]; go_function: GO:0004335 - galactokinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016301 - kinase activity [Evidence IEA]; go_function: GO:0016773 - phosphotransferase activity, alcohol group as acceptor [Evidence IEA]; go_process: GO:0006012 - galactose metabolic process [Evidence IEA]; go_process: GO:0046835 - carbohydrate phosphorylation [Evidence IEA] AKAW2_70357S COG:E; EggNog:ENOG410PFW3; InterPro:IPR012846,IPR012001,IPR012000,IPR011766, IPR029061,IPR039368,IPR029035,IPR000399; PFAM:PF02775,PF02776,PF00205; go_function: GO:0000287 - magnesium ion binding [Evidence IEA]; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0003984 - acetolactate synthase activity [Evidence IEA]; go_function: GO:0030976 - thiamine pyrophosphate binding [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_process: GO:0009082 - branched-chain amino acid biosynthetic process [Evidence IEA] AKAW2_70358S COG:O; EggNog:ENOG410PK6K; InterPro:IPR011016,IPR013083; PFAM:PF12906,PF11793; TransMembrane:4 (i167-191o211-229i387-409o435-454i); go_function: GO:0008270 - zinc ion binding [Evidence IEA] AKAW2_70359S COG:S; EggNog:ENOG410PRBG; InterPro:IPR042831; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_process: GO:0032543 - mitochondrial translation [Evidence IEA] AKAW2_70360A COG:S; EggNog:ENOG410PIRK; InterPro:IPR005225,IPR001806,IPR027417,IPR003578; PFAM:PF00025,PF08477,PF00071; go_function: GO:0003924 - GTPase activity [Evidence IEA]; go_function: GO:0005525 - GTP binding [Evidence IEA]; go_process: GO:0007264 - small GTPase mediated signal transduction [Evidence IEA] AKAW2_70361A COG:C; EggNog:ENOG410PV1Z; InterPro:IPR036188,IPR002938; PFAM:PF01494; go_function: GO:0071949 - FAD binding [Evidence IEA] AKAW2_70363A COG:E; EggNog:ENOG410PKRR; InterPro:IPR036412,IPR023198,IPR023214 AKAW2_70364S COG:E; EggNog:ENOG410Q22P; InterPro:IPR004841; PFAM:PF13520,PF00324; TransMembrane:12 (i46-63o69-90i117-144o156-178i190-210o236-255i267-287o319- 343i370-389o395-421i442-464o476-494i); go_component: GO:0016020 - membrane [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_70365S COG:I; EggNog:ENOG410PJU0; InterPro:IPR042099,IPR000873,IPR020845; PFAM:PF00501 AKAW2_70366S COG:S; EggNog:ENOG410PKGG; InterPro:IPR025279; PFAM:PF13945 AKAW2_70367A BUSCO:EOG09260T28; COG:U; EggNog:ENOG410PGCB; InterPro:IPR005378,IPR042491; PFAM:PF03635; go_component: GO:0030906 - retromer, cargo-selective complex [Evidence IEA]; go_process: GO:0015031 - protein transport [Evidence IEA]; go_process: GO:0042147 - retrograde transport, endosome to Golgi [Evidence IEA] AKAW2_70368S COG:T; EggNog:ENOG410PJQ6; InterPro:IPR002110,IPR027417,IPR007111,IPR036770, IPR020683,IPR031359; PFAM:PF05729,PF12796,PF13637,PF17100; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_70369A SECRETED:SignalP(1-16) AKAW2_70370A COG:K; EggNog:ENOG410PKZ5; InterPro:IPR015943,IPR036322; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_70371S COG:S; EggNog:ENOG410PKVD; InterPro:IPR013744,IPR029058; PFAM:PF08538 AKAW2_70372A BUSCO:EOG09264272; CAZy:GT2_Glycos_transf; COG:M; EggNog:ENOG410PGFH; InterPro:IPR001173,IPR029044,IPR039528; PFAM:PF00535,PF13641; go_function: GO:0004582 - dolichyl-phosphate beta-D-mannosyltransferase activity [Evidence IEA] AKAW2_70373A COG:S; EggNog:ENOG410PZN1 AKAW2_70374A COG:S; EggNog:ENOG410PQ9Z; TransMembrane:1 (o360-386i) AKAW2_70375A InterPro:IPR001810,IPR036047,IPR032675; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_70376S COG:A; EggNog:ENOG410PHKU; InterPro:IPR006569,IPR035967,IPR000061; PFAM:PF01805; go_function: GO:0003723 - RNA binding [Evidence IEA]; go_process: GO:0006396 - RNA processing [Evidence IEA] AKAW2_70378S BUSCO:EOG09265BCT; COG:U; EggNog:ENOG410PP3P; InterPro:IPR018222,IPR032710,IPR002075; PFAM:PF02136 AKAW2_70377A COG:S; EggNog:ENOG410PIXB; InterPro:IPR006603; PFAM:PF04193; TransMembrane:7 (o16-35i47-70o90-117i137-157o163-183i195-214o226-249i) AKAW2_70379S COG:S; EggNog:ENOG410PKXI; InterPro:IPR018803; PFAM:PF10281; SECRETED:SignalP(1-21) AKAW2_70380A BUSCO:EOG09264Z3D; COG:S; EggNog:ENOG410PP68; InterPro:IPR036400,IPR001199; PFAM:PF00173; TransMembrane:1 (o14-35i) AKAW2_70381S COG:S; EggNog:ENOG410PRX5 AKAW2_70382A COG:S; EggNog:ENOG410PSPY; InterPro:IPR015157; PFAM:PF09072 AKAW2_70383S COG:T; EggNog:ENOG410PGRU; InterPro:IPR017441,IPR008271,IPR044092,IPR000719, IPR011009; PFAM:PF07714,PF00069; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0004674 - protein serine/threonine kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA]; go_process: GO:0045292 - mRNA cis splicing, via spliceosome [Evidence IEA] AKAW2_70384S COG:T; EggNog:ENOG410Q2MY; InterPro:IPR017441,IPR008271,IPR000719,IPR011009; PFAM:PF07714,PF00069; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_70385A COG:Q; EggNog:ENOG410PI9R; InterPro:IPR002347,IPR036291,IPR020904; PFAM:PF00106,PF13561,PF08659; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_70386A COG:S; EggNog:ENOG410Q1TM; InterPro:IPR036864,IPR001138; PFAM:PF00172; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_70387A COG:T; EggNog:ENOG410PM7P; InterPro:IPR004254; PFAM:PF03006; TransMembrane:8 (i58-77o83-104i116-135o155-176i183-202o214-232i244- 265o285-305i); go_component: GO:0016021 - integral component of membrane [Evidence IEA] AKAW2_70388S COG:S; EggNog:ENOG410PKB9 AKAW2_70389A COG:S; EggNog:ENOG410PIG2; InterPro:IPR011990; PFAM:PF14559; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_70390S COG:U; EggNog:ENOG410PKCP; InterPro:IPR019365; PFAM:PF10233; TransMembrane:4 (i12-36o42-65i85-103o109-128i); go_component: GO:0016021 - integral component of membrane [Evidence IEA] AKAW2_70391S COG:J; EggNog:ENOG410PFZ7; InterPro:IPR019382,IPR000717; PFAM:PF10255; TransMembrane:2 (i195-217o229-252i); go_component: GO:0005737 - cytoplasm [Evidence IEA]; go_component: GO:0005852 - eukaryotic translation initiation factor 3 complex [Evidence IEA]; go_function: GO:0003743 - translation initiation factor activity [Evidence IEA] AKAW2_70392A BUSCO:EOG09265G5K; COG:C,U; EggNog:ENOG410PPRV; InterPro:IPR016092,IPR000361,IPR035903; PFAM:PF01521; go_function: GO:0005198 - structural molecule activity [Evidence IEA]; go_function: GO:0051536 - iron-sulfur cluster binding [Evidence IEA]; go_process: GO:0097428 - protein maturation by iron-sulfur cluster transfer [Evidence IEA] AKAW2_70393S COG:E; EggNog:ENOG410PH7Q; InterPro:IPR000192,IPR015422,IPR015424,IPR015421, IPR010111; go_component: GO:0005737 - cytoplasm [Evidence IEA]; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0030170 - pyridoxal phosphate binding [Evidence IEA]; go_function: GO:0030429 - kynureninase activity [Evidence IEA]; go_process: GO:0006569 - tryptophan catabolic process [Evidence IEA]; go_process: GO:0009435 - NAD biosynthetic process [Evidence IEA] AKAW2_70394A BUSCO:EOG09264KSI; COG:S; EggNog:ENOG410PNJT; InterPro:IPR009445; PFAM:PF06417; TransMembrane:2 (o86-107i133-153o) AKAW2_70395S COG:U; EggNog:ENOG410PHH5; InterPro:IPR016024,IPR011989,IPR026739,IPR016342, IPR002553; PFAM:PF01602,PF12717; go_component: GO:0030117 - membrane coat [Evidence IEA]; go_function: GO:0030276 - clathrin binding [Evidence IEA]; go_process: GO:0006886 - intracellular protein transport [Evidence IEA]; go_process: GO:0015031 - protein transport [Evidence IEA]; go_process: GO:0016192 - vesicle-mediated transport [Evidence IEA] AKAW2_70396A COG:S; EggNog:ENOG410PJH6; InterPro:IPR019339,IPR022209; PFAM:PF10197,PF12542 AKAW2_70397A COG:Z; EggNog:ENOG410PIH1; InterPro:IPR030506,IPR036028,IPR035552,IPR001452; PFAM:PF00018,PF07653; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_70398S COG:S; EggNog:ENOG410PPSI; InterPro:IPR007308,IPR038534,IPR039693; PFAM:PF04181; go_function: GO:0008420 - RNA polymerase II CTD heptapeptide repeat phosphatase activity [Evidence IEA]; go_function: GO:0043175 - RNA polymerase core enzyme binding [Evidence IEA]; go_process: GO:0070940 - dephosphorylation of RNA polymerase II C-terminal domain [Evidence IEA] AKAW2_70399A COG:J; EggNog:ENOG410PMV6; InterPro:IPR036401,IPR018273,IPR001210; PFAM:PF00833; go_component: GO:0005840 - ribosome [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_process: GO:0006412 - translation [Evidence IEA] AKAW2_70400A COG:S; EggNog:ENOG410PG7D; InterPro:IPR016712; PFAM:PF11709 AKAW2_70401A COG:V; EggNog:ENOG410PJT2; InterPro:IPR001509,IPR036291; PFAM:PF01073,PF16363,PF07993,PF01370; go_function: GO:0003824 - catalytic activity [Evidence IEA] AKAW2_70402S COG:L; EggNog:ENOG410PGA0; InterPro:IPR016024,IPR011989,IPR036738,IPR024585, IPR003151,IPR036940,IPR018936,IPR009076,IPR021133, IPR026683,IPR011009,IPR000403,IPR014009,IPR000357; PFAM:PF11865,PF00454,PF02260,PF08771,PF02985, PF02259; go_function: GO:0004674 - protein serine/threonine kinase activity [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_function: GO:0016301 - kinase activity [Evidence IEA]; go_function: GO:0044877 - protein-containing complex binding [Evidence IEA] AKAW2_70403S COG:S; EggNog:ENOG410PHP9; InterPro:IPR026749; TransMembrane:7 (i72-92o112-129i216-235o340-364i385-408o420-445i465-484o) AKAW2_70404S COG:S; EggNog:ENOG410Q2GD; InterPro:IPR002523; TransMembrane:2 (i321-341o347-368i); go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0046873 - metal ion transmembrane transporter activity [Evidence IEA]; go_process: GO:0030001 - metal ion transport [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_70405S COG:G; EggNog:ENOG410PKMR; InterPro:IPR004104,IPR000683,IPR036291; PFAM:PF02894,PF01408; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA] AKAW2_70406A COG:S; EggNog:ENOG410PH5C; InterPro:IPR007828; PFAM:PF05153; go_component: GO:0005737 - cytoplasm [Evidence IEA]; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0050113 - inositol oxygenase activity [Evidence IEA]; go_process: GO:0019310 - inositol catabolic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_70408S COG:C; EggNog:ENOG410PFT7; InterPro:IPR018170,IPR020471,IPR036812,IPR023210; PFAM:PF00248; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_70409A COG:S; EggNog:ENOG410Q0DH AKAW2_70410A COG:S; EggNog:ENOG410PJBR AKAW2_70411S COG:G,M; EggNog:ENOG410PN77; InterPro:IPR036291,IPR016040; PFAM:PF13460,PF01370 AKAW2_70412A COG:I; EggNog:ENOG410PGIY; InterPro:IPR000873,IPR020845,IPR042099,IPR025110; PFAM:PF00501,PF13193 AKAW2_70413A COG:S; EggNog:ENOG410Q211; TransMembrane:7 (o12-35i47-71o91-113i125-146o171-196i208-228o248-273i) AKAW2_70414A COG:Q; EggNog:ENOG410PKKR; InterPro:IPR017871,IPR027417,IPR003593,IPR011527, IPR003439,IPR036640; PFAM:PF00005,PF00664; TransMembrane:18 (o20-42i62-87o93-113i125-142o154-175i196-213o252-270i277- 295o307-328i378-397o403-424i480-497o509-526i881-903o923- 949i1015-1039o1108-1129i1136-1159o); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA]; go_function: GO:0042626 - ATPase-coupled transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_70415S COG:S; EggNog:ENOG410PJJ3; InterPro:IPR009836 AKAW2_70416A COG:O; EggNog:ENOG410PGQH; InterPro:IPR027417,IPR041569,IPR003959,IPR029067, IPR015342,IPR003593,IPR003960,IPR025653,IPR009010; PFAM:PF09262,PF17862,PF00004; go_component: GO:0005777 - peroxisome [Evidence IEA]; go_component: GO:0005778 - peroxisomal membrane [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA]; go_process: GO:0006625 - protein targeting to peroxisome [Evidence IEA]; go_process: GO:0007031 - peroxisome organization [Evidence IEA] AKAW2_70417S COG:L; EggNog:ENOG410PGHK; InterPro:IPR027417,IPR003593,IPR001208,IPR041562, IPR027925,IPR033762,IPR031327,IPR008050,IPR012340, IPR018525; PFAM:PF00493,PF17855,PF17207,PF07728,PF14551; go_component: GO:0042555 - MCM complex [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0003678 - DNA helicase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006260 - DNA replication [Evidence IEA]; go_process: GO:0006270 - DNA replication initiation [Evidence IEA]; go_process: GO:0032508 - DNA duplex unwinding [Evidence IEA] AKAW2_70418A COG:S; EggNog:ENOG410PU1N; SECRETED:SignalP(1-20) AKAW2_70419A COG:G; EggNog:ENOG410PGC8; InterPro:IPR029056,IPR017953,IPR000631; PFAM:PF01256; go_function: GO:0052855 - ADP-dependent NAD(P)H-hydrate dehydratase activity [Evidence IEA] AKAW2_70420A COG:G; EggNog:ENOG410PGC8; InterPro:IPR029056,IPR000631; go_function: GO:0052855 - ADP-dependent NAD(P)H-hydrate dehydratase activity [Evidence IEA] AKAW2_70421A COG:S; EggNog:ENOG410PU25; InterPro:IPR013256; PFAM:PF08243 AKAW2_70422S COG:J; EggNog:ENOG410PRUB; InterPro:IPR044076,IPR027534,IPR001859,IPR038716; PFAM:PF00428; SECRETED:SignalP(1-20); go_component: GO:0005840 - ribosome [Evidence IEA]; go_component: GO:0022625 - cytosolic large ribosomal subunit [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_process: GO:0002182 - cytoplasmic translational elongation [Evidence IEA]; go_process: GO:0006412 - translation [Evidence IEA]; go_process: GO:0006414 - translational elongation [Evidence IEA] AKAW2_70423S BUSCO:EOG092658SK; COG:J; EggNog:ENOG410PIWK; InterPro:IPR002222,IPR005713,IPR020934,IPR023575; PFAM:PF00203; go_component: GO:0005840 - ribosome [Evidence IEA]; go_component: GO:0015935 - small ribosomal subunit [Evidence IEA]; go_function: GO:0003723 - RNA binding [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_process: GO:0006412 - translation [Evidence IEA] AKAW2_70424A COG:B; EggNog:ENOG410PP8F; InterPro:IPR001214,IPR002893; PFAM:PF01753,PF00856; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_70425A COG:F; EggNog:ENOG410PH1U; InterPro:IPR011607,IPR036914,IPR036897,IPR011761, IPR016185,IPR005479,IPR005483,IPR013815,IPR005480, IPR006275; PFAM:PF02786,PF02222,PF07478,PF02787; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0046872 - metal ion binding [Evidence IEA]; go_process: GO:0006807 - nitrogen compound metabolic process [Evidence IEA] AKAW2_70426S COG:S; EggNog:ENOG410PRNV AKAW2_70427S COG:S; EggNog:ENOG410PI8D; InterPro:IPR000504,IPR012677,IPR035979; PFAM:PF00076,PF14605; go_function: GO:0003676 - nucleic acid binding [Evidence IEA] AKAW2_70428A COG:S; EggNog:ENOG410QE02 AKAW2_70429A COG:U,Y; EggNog:ENOG410PHDR; InterPro:IPR001494,IPR016024,IPR011989,IPR013713; PFAM:PF03810; go_function: GO:0008536 - Ran GTPase binding [Evidence IEA]; go_process: GO:0006886 - intracellular protein transport [Evidence IEA] AKAW2_70430A COG:A; EggNog:ENOG410PHEF; InterPro:IPR012961,IPR016438,IPR027417,IPR001650, IPR014001,IPR040801,IPR011545,IPR025696; PFAM:PF17911,PF13234,PF08148,PF00270,PF00271; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0003723 - RNA binding [Evidence IEA]; go_function: GO:0003724 - RNA helicase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006401 - RNA catabolic process [Evidence IEA] AKAW2_70431A COG:S; EggNog:ENOG410PMX0; InterPro:IPR015943,IPR019417,IPR036322; PFAM:PF10313; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_70432S COG:O; EggNog:ENOG410PFA0; InterPro:IPR018181,IPR029047,IPR029048,IPR012725, IPR013126,IPR043129; PFAM:PF00012,PF06723; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0051082 - unfolded protein binding [Evidence IEA]; go_process: GO:0006457 - protein folding [Evidence IEA] AKAW2_70433S COG:S; EggNog:ENOG410Q1WS AKAW2_70434A COG:F; EggNog:ENOG410QEAV; InterPro:IPR029063,IPR019410; PFAM:PF10294 AKAW2_70435S COG:I; EggNog:ENOG410PF89; InterPro:IPR042099,IPR000873,IPR020845; PFAM:PF00501 AKAW2_70436S COG:S; EggNog:ENOG410PTUP AKAW2_70438A COG:S; EggNog:ENOG410PNW0; InterPro:IPR008967,IPR037141,IPR024061; PFAM:PF05224; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0003700 - DNA-binding transcription factor activity [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_70439A BUSCO:EOG0926489S; COG:J; EggNog:ENOG410PI34; InterPro:IPR000504,IPR024675,IPR017334,IPR035979, IPR012677,IPR034240; PFAM:PF12353,PF00076; go_component: GO:0005737 - cytoplasm [Evidence IEA]; go_component: GO:0005852 - eukaryotic translation initiation factor 3 complex [Evidence IEA]; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0003743 - translation initiation factor activity [Evidence IEA] AKAW2_70440A COG:O; EggNog:ENOG410PK5G; InterPro:IPR013126,IPR043129 AKAW2_70442A COG:Q; EggNog:ENOG410PISI; InterPro:IPR001248,IPR026030,IPR038271; PFAM:PF02133; TransMembrane:11 (o76-97i104-128o148-167i179-202o208-226i280-306o326- 352i378-397o409-427i447-464o484-500i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_70443A COG:E; EggNog:ENOG410PMI1; InterPro:IPR002293,IPR004840; PFAM:PF13520,PF00324; TransMembrane:13 (o37-59i66-86o92-108i120-141o161-181i188-206o226-246i267- 292o324-347i368-388o400-423i435-458o470-490i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0006865 - amino acid transport [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_70444S COG:Q; EggNog:ENOG410PI5X; InterPro:IPR036396,IPR001128,IPR017972,IPR002401; PFAM:PF00067; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_70445A COG:S; EggNog:ENOG410PP0S; InterPro:IPR037401,IPR032710; PFAM:PF13577 AKAW2_70446A COG:S; EggNog:ENOG410PJZ7; InterPro:IPR013785,IPR004136; PFAM:PF03060,PF00478; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0018580 - nitronate monooxygenase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_70447S BUSCO:EOG09260LJ8; COG:H; EggNog:ENOG410PFZP; InterPro:IPR006390,IPR000489,IPR011005,IPR000550, IPR035907; PFAM:PF01288,PF00809; go_function: GO:0003848 - 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity [Evidence IEA]; go_function: GO:0004156 - dihydropteroate synthase activity [Evidence IEA]; go_process: GO:0009396 - folic acid-containing compound biosynthetic process [Evidence IEA]; go_process: GO:0042558 - pteridine-containing compound metabolic process [Evidence IEA]; go_process: GO:0044237 - cellular metabolic process [Evidence IEA] AKAW2_70449A COG:T; EggNog:ENOG410PFI3; InterPro:IPR001164,IPR037278,IPR038508; PFAM:PF01412; go_function: GO:0005096 - GTPase activator activity [Evidence IEA] AKAW2_70450S COG:U; EggNog:ENOG410PQ5N; InterPro:IPR038552,IPR013261; PFAM:PF08695,PF08294; TransMembrane:1 (i91-112o); go_component: GO:0005744 - TIM23 mitochondrial import inner membrane translocase complex [Evidence IEA]; go_process: GO:0030150 - protein import into mitochondrial matrix [Evidence IEA] AKAW2_70451A COG:M; EggNog:ENOG410PH4Q; InterPro:IPR034610,IPR029065,IPR036849,IPR013342, IPR013341,IPR029017,IPR018110; PFAM:PF13378,PF02746; go_function: GO:0050023 - L-fuconate dehydratase activity [Evidence IEA]; go_process: GO:0009063 - cellular amino acid catabolic process [Evidence IEA]; go_process: GO:0016052 - carbohydrate catabolic process [Evidence IEA] AKAW2_70452A COG:A; EggNog:ENOG410PIQ0; InterPro:IPR035979,IPR036483,IPR034268,IPR012677, IPR002483; PFAM:PF01480; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_process: GO:0006397 - mRNA processing [Evidence IEA] AKAW2_70453S BUSCO:EOG09261RWJ; COG:G; EggNog:ENOG410PF7S; InterPro:IPR035476,IPR035482,IPR018189,IPR001672, IPR023096; PFAM:PF00342; go_function: GO:0004347 - glucose-6-phosphate isomerase activity [Evidence IEA]; go_process: GO:0006094 - gluconeogenesis [Evidence IEA]; go_process: GO:0006096 - glycolytic process [Evidence IEA] AKAW2_70454S COG:S; EggNog:ENOG410PQYU; SECRETED:SignalP(1-28); TransMembrane:1 (n16-23c28/29o271-292i) AKAW2_70455A COG:S; EggNog:ENOG410PTXF; InterPro:IPR001911; PFAM:PF01165; go_component: GO:0005840 - ribosome [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_process: GO:0006412 - translation [Evidence IEA] AKAW2_70456S BUSCO:EOG092658QH; COG:D; EggNog:ENOG410QDRU; InterPro:IPR001763,IPR036873; PFAM:PF00581 AKAW2_70457A COG:S; EggNog:ENOG410PHVH; InterPro:IPR003788,IPR029063; PFAM:PF02636 AKAW2_70458A COG:S; EggNog:ENOG410PRDV; InterPro:IPR035979,IPR012677; go_function: GO:0003676 - nucleic acid binding [Evidence IEA] AKAW2_70459A COG:S; EggNog:ENOG410PYZH AKAW2_70460S COG:T; EggNog:ENOG410PKCJ; InterPro:IPR000719,IPR011009,IPR017441; PFAM:PF00069; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_70461S COG:S; EggNog:ENOG410Q1EI AKAW2_70462A COG:T; EggNog:ENOG410PGBR; InterPro:IPR000719,IPR011009,IPR008271; PFAM:PF07714,PF00069; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_70463S COG:P; EggNog:ENOG410PJAA; InterPro:IPR036423,IPR024134,IPR001424,IPR006121, IPR036163; PFAM:PF00403,PF00080; go_function: GO:0046872 - metal ion binding [Evidence IEA]; go_process: GO:0006801 - superoxide metabolic process [Evidence IEA]; go_process: GO:0030001 - metal ion transport [Evidence IEA] AKAW2_70464S COG:T; EggNog:ENOG410PGC0; InterPro:IPR011990,IPR019734,IPR034892,IPR013026, IPR000270; PFAM:PF13181,PF00564; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_70465S COG:U; EggNog:ENOG410PNJX; InterPro:IPR000727,IPR019529; PFAM:PF10496; TransMembrane:1 (o338-356i) AKAW2_70466A COG:E; EggNog:ENOG410PGES; InterPro:IPR004839,IPR000796,IPR015424,IPR015421, IPR015422; PFAM:PF00155; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0008483 - transaminase activity [Evidence IEA]; go_function: GO:0030170 - pyridoxal phosphate binding [Evidence IEA]; go_process: GO:0006520 - cellular amino acid metabolic process [Evidence IEA]; go_process: GO:0009058 - biosynthetic process [Evidence IEA] AKAW2_70467A COG:O; EggNog:ENOG410PK48; InterPro:IPR001841,IPR013083; PFAM:PF17123,PF13923,PF00097,PF13639; SECRETED:SignalP(1-56); TransMembrane:2 (n11-22c34/35o44-64i248-270o) AKAW2_70468A TransMembrane:1 (o6-23i) AKAW2_70469S COG:S; EggNog:ENOG410PT8X AKAW2_70470S COG:Q; EggNog:ENOG410PIVP; InterPro:IPR008775; PFAM:PF05721 AKAW2_70471S CAZy:AA3; COG:E; EggNog:ENOG410PJ63; InterPro:IPR007867,IPR012132,IPR000172,IPR036188; PFAM:PF05199; SECRETED:SignalP(1-19); go_function: GO:0016614 - oxidoreductase activity, acting on CH-OH group of donors [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_70472A COG:P; EggNog:ENOG410PH6F; InterPro:IPR011990,IPR031350; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_70474S SECRETED:SignalP(1-20) AKAW2_70475A COG:S; EggNog:ENOG410Q2VR; InterPro:IPR002921,IPR029058; PFAM:PF01764; SECRETED:SignalP(1-20); go_process: GO:0006629 - lipid metabolic process [Evidence IEA] AKAW2_70476A COG:Q; EggNog:ENOG410PM3R; InterPro:IPR001128,IPR017972,IPR002401,IPR036396; PFAM:PF00067; TransMembrane:1 (n8-19c24/25o210-233i); go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_70477A COG:S; EggNog:ENOG410PKKX; TransMembrane:7 (o12-32i44-66o78-101i122-144o164-187i199-218o238-258i) AKAW2_70478A COG:S; EggNog:ENOG410PJGK; InterPro:IPR000073,IPR029058 AKAW2_70479A COG:G; EggNog:ENOG410PJ3A; InterPro:IPR005829,IPR005828,IPR003663,IPR036259, IPR020846; PFAM:PF00083,PF07690; TransMembrane:12 (i23-41o75-95i102-123o129-150i162-180o200-217i291-313o328- 347i359-381o393-417i429-449o461-483i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_70480A COG:C; EggNog:ENOG410PVAE; InterPro:IPR001030,IPR018136,IPR006248,IPR036008, IPR015931,IPR015932,IPR015928,IPR000573; PFAM:PF00694,PF00330; go_function: GO:0003994 - aconitate hydratase activity [Evidence IEA]; go_function: GO:0051539 - 4 iron, 4 sulfur cluster binding [Evidence IEA]; go_process: GO:0006099 - tricarboxylic acid cycle [Evidence IEA] AKAW2_70481S COG:H; EggNog:ENOG410PM39; InterPro:IPR005493,IPR036704; PFAM:PF03737 AKAW2_70482A COG:S; EggNog:ENOG410PN9P; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; TransMembrane:2 (o353-374i395-418o); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_70483S COG:S; EggNog:ENOG410PRJP; InterPro:IPR006680,IPR032466; PFAM:PF04909; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_70484S COG:S; EggNog:ENOG410PVHI; InterPro:IPR001138,IPR036864; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_70485S COG:S; EggNog:ENOG410PIYI AKAW2_70486A TransMembrane:1 (o30-49i) AKAW2_70487S COG:P; EggNog:ENOG410PFW2; InterPro:IPR018303,IPR023298,IPR023299,IPR001757, IPR004014,IPR036412,IPR006534,IPR008250,IPR023214; PFAM:PF00122,PF00690,PF00702; TransMembrane:10 (i123-142o148-167i344-363o375-406i738-759o765-789i801- 825o837-855i867-887o918-936i); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0000166 - nucleotide binding [Evidence IEA]; go_function: GO:0008553 - proton-exporting ATPase activity, phosphorylative mechanism [Evidence IEA]; go_process: GO:0120029 - proton export across plasma membrane [Evidence IEA] AKAW2_70488S COG:S; EggNog:ENOG410PYY4; SECRETED:SignalP(1-19) AKAW2_70489S TransMembrane:1 (i63-81o) AKAW2_70491A COG:E; EggNog:ENOG410PJ8V; InterPro:IPR013057; PFAM:PF01490; TransMembrane:11 (i64-84o90-111i138-161o167-186i198-219o247-267i279- 301o321-342i363-382o394-415i427-449o) AKAW2_70492S COG:S; EggNog:ENOG410Q1CF; InterPro:IPR029063 AKAW2_70493S COG:S; EggNog:ENOG410PVEY; InterPro:IPR000073,IPR029058; MEROPS:MER0031616; PFAM:PF12697 AKAW2_70494A TransMembrane:1 (n14-21c25/26o49-66i) AKAW2_70496A COG:C,G; EggNog:ENOG410PFEC AKAW2_70498S COG:G; EggNog:ENOG410QEDA; InterPro:IPR013078,IPR029033; PFAM:PF00300 AKAW2_70499S TransMembrane:2 (o6-24i31-60o) AKAW2_70500A COG:S; EggNog:ENOG410PMZY; InterPro:IPR002410,IPR000073,IPR029058,IPR005945; MEROPS:MER0003537; PFAM:PF02129,PF12146,PF00561,PF12697; go_function: GO:0008233 - peptidase activity [Evidence IEA]; go_process: GO:0006508 - proteolysis [Evidence IEA] AKAW2_70501S COG:S; EggNog:ENOG410PQ1B; TransMembrane:5 (n3-14c22/23o38-60i72-91o111-134i146-168o180-202i) AKAW2_70502S COG:E; EggNog:ENOG410PFXK; InterPro:IPR002293; PFAM:PF00324,PF13520; TransMembrane:8 (i42-59o79-103i124-152o172-192i199-218o238-261i282- 305o325-350i); go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_70503A COG:O; EggNog:ENOG410Q8M2; InterPro:IPR036249,IPR036282,IPR010987,IPR004045, IPR004046; PFAM:PF00043,PF14497; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0006749 - glutathione metabolic process [Evidence IEA] AKAW2_70504A CAZy:CBM43; CAZy:GH72; COG:S; EggNog:ENOG410PFK7; InterPro:IPR012946,IPR017853,IPR004886; PFAM:PF07983,PF03198; SECRETED:SignalP(1-19); TransMembrane:1 (n3-14c19/20o505-524i) AKAW2_70506S CAZy:GH128; COG:S; EggNog:ENOG410PWPA; InterPro:IPR017853,IPR024655; PFAM:PF11790; SECRETED:SignalP(1-19) AKAW2_70507A COG:F; EggNog:ENOG410PMHQ; InterPro:IPR000845,IPR035994; TransMembrane:2 (i207-225o231-252i); go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_process: GO:0009116 - nucleoside metabolic process [Evidence IEA] AKAW2_70508A COG:S; EggNog:ENOG410PTCG; SECRETED:SignalP(1-22); TransMembrane:1 (n7-18c23/24o214-238i) AKAW2_70509A COG:P; EggNog:ENOG410PGDX; InterPro:IPR020846,IPR005828,IPR036259; PFAM:PF00083; TransMembrane:10 (i43-61o81-104i116-137o143-163i183-206o218-238i259- 278o308-328i340-370o429-449i); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_70510A COG:S; EggNog:ENOG410PM2P AKAW2_70511A COG:E; EggNog:ENOG410PVMF; InterPro:IPR036526,IPR003010; PFAM:PF00795; go_process: GO:0006807 - nitrogen compound metabolic process [Evidence IEA] AKAW2_70512S COG:E; EggNog:ENOG410PJ7Z; InterPro:IPR020846,IPR005828,IPR036259; PFAM:PF07690,PF00083; TransMembrane:9 (o6-26i38-56o68-91i103-120o132-149i218-237o257-278i285- 304o316-334i); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_70513S COG:Q; EggNog:ENOG410PWPI; InterPro:IPR036291,IPR002347; PFAM:PF08659,PF00106,PF13561; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_70514S COG:G; EggNog:ENOG410Q1CY; InterPro:IPR036237 AKAW2_70515A COG:Q; EggNog:ENOG410PWUQ; InterPro:IPR002347,IPR036291,IPR020904; PFAM:PF00106,PF13561,PF08659; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_70516S SECRETED:SignalP(1-20) AKAW2_70517S COG:S; EggNog:ENOG410PV93; InterPro:IPR008979,IPR029058,IPR005674,IPR013736, IPR000383; PFAM:PF02129,PF08530; go_function: GO:0008239 - dipeptidyl-peptidase activity [Evidence IEA]; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_70518A COG:S; EggNog:ENOG410PWSH; InterPro:IPR011008,IPR009799; PFAM:PF07110; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA] AKAW2_70519S COG:Q; EggNog:ENOG410PKEZ; InterPro:IPR013149,IPR036291,IPR020843,IPR011032; PFAM:PF00107; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_70520S COG:S; EggNog:ENOG410PUF0; InterPro:IPR036236,IPR036864,IPR007219,IPR013087, IPR001138; PFAM:PF00172,PF04082,PF00096; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_70521A SECRETED:SignalP(1-19) AKAW2_70522A COG:S; EggNog:ENOG410PNB3; InterPro:IPR023149,IPR029063,IPR041698; PFAM:PF05401,PF13489,PF13649,PF08242,PF08241, PF05175,PF13847; go_function: GO:0030798 - trans-aconitate 2-methyltransferase activity [Evidence IEA] AKAW2_70523A COG:Q; EggNog:ENOG410PGYE; InterPro:IPR001128,IPR017972,IPR002401,IPR036396; PFAM:PF00067; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_70524A BUSCO:EOG09261666; COG:H; EggNog:ENOG410PI1A; InterPro:IPR004408,IPR019197,IPR004143,IPR029062; PFAM:PF03099,PF09825; go_function: GO:0004077 - biotin-[acetyl-CoA-carboxylase] ligase activity [Evidence IEA]; go_process: GO:0006464 - cellular protein modification process [Evidence IEA] AKAW2_70525S COG:O; EggNog:ENOG410PQYJ; InterPro:IPR039870; go_component: GO:0005758 - mitochondrial intermembrane space [Evidence IEA]; go_process: GO:0033617 - mitochondrial cytochrome c oxidase assembly [Evidence IEA] AKAW2_70526S BUSCO:EOG0926484N; COG:L; EggNog:ENOG410PMX3; InterPro:IPR009446; PFAM:PF06420; go_component: GO:0000262 - mitochondrial chromosome [Evidence IEA]; go_function: GO:0003697 - single-stranded DNA binding [Evidence IEA]; go_process: GO:0000002 - mitochondrial genome maintenance [Evidence IEA]; go_process: GO:0006281 - DNA repair [Evidence IEA] AKAW2_70527A COG:M; EggNog:ENOG410PF8H; InterPro:IPR010920,IPR011992,IPR006685,IPR002048, IPR018247; PFAM:PF00924; TransMembrane:6 (i133-155o167-193i214-235o255-272i489-515o521-544i); go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0005509 - calcium ion binding [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_70528A COG:T; EggNog:ENOG410PJCI; InterPro:IPR000719,IPR011009; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_70529S COG:Q; EggNog:ENOG410PKH2; InterPro:IPR001128,IPR017972,IPR002401,IPR036396; PFAM:PF00067; TransMembrane:1 (n2-13c18/19o448-465i); go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_70530S COG:S; EggNog:ENOG410PKUF; InterPro:IPR001077,IPR036388,IPR016461,IPR029063, IPR036390; PFAM:PF00891; go_function: GO:0008168 - methyltransferase activity [Evidence IEA]; go_function: GO:0008171 - O-methyltransferase activity [Evidence IEA] AKAW2_70531S COG:I; EggNog:ENOG410PFMX; InterPro:IPR001199,IPR012171,IPR005804,IPR036400; PFAM:PF00173,PF00487; TransMembrane:5 (i209-234o254-276i335-356o376-395i402-421o); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0006629 - lipid metabolic process [Evidence IEA] AKAW2_70532A COG:S; EggNog:ENOG410PWFA; InterPro:IPR000845,IPR035994; PFAM:PF01048; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_process: GO:0009116 - nucleoside metabolic process [Evidence IEA] AKAW2_70533S COG:M; EggNog:ENOG410PYRX; InterPro:IPR002110,IPR036770,IPR025676,IPR020683; PFAM:PF12796,PF00023,PF13637,PF13606,PF14420; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_70534S COG:G; EggNog:ENOG410QDAZ; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i62-84o104-123i130-150o156-179i191-211o223-247i268- 286o306-324i331-352o358-380i392-415o427-445i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_70535A COG:K; EggNog:ENOG410PI56; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; TransMembrane:1 (o523-541i); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_70536A COG:S; EggNog:ENOG410Q2V2; InterPro:IPR029058; SECRETED:SignalP(1-24) AKAW2_70537A CAZy:GH5; COG:G; EggNog:ENOG410PGYW; InterPro:IPR001547,IPR035971,IPR017853,IPR000254; PFAM:PF00734,PF00150; go_component: GO:0005576 - extracellular region [Evidence IEA]; go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_function: GO:0030248 - cellulose binding [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA]; go_process: GO:0071704 - organic substance metabolic process [Evidence IEA] AKAW2_70538A COG:S; EggNog:ENOG410PNAQ; InterPro:IPR008551; PFAM:PF05742 AKAW2_70539S COG:V; EggNog:ENOG410PNU1; InterPro:IPR004345; PFAM:PF03134; TransMembrane:2 (i7-26o38-61i) AKAW2_70541S COG:J; EggNog:ENOG410QDMB; InterPro:IPR016024,IPR016021,IPR036211,IPR022745, IPR003890; PFAM:PF02854,PF12152; go_function: GO:0003723 - RNA binding [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_70542A COG:T; EggNog:ENOG410PHAI; InterPro:IPR006015,IPR014729,IPR006016; PFAM:PF00582 AKAW2_70543A COG:S; EggNog:ENOG410PPZV; InterPro:IPR037738 AKAW2_70544A COG:P; EggNog:ENOG410PFCK; InterPro:IPR003445,IPR015958,IPR004773; PFAM:PF02386; TransMembrane:10 (i21-44o73-98i262-284o304-321i333-358o396-416i428-451o457- 477i515-532o544-568i); go_component: GO:0005887 - integral component of plasma membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0008324 - cation transmembrane transporter activity [Evidence IEA]; go_function: GO:0015079 - potassium ion transmembrane transporter activity [Evidence IEA]; go_process: GO:0006812 - cation transport [Evidence IEA]; go_process: GO:0030007 - cellular potassium ion homeostasis [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA]; go_process: GO:0071805 - potassium ion transmembrane transport [Evidence IEA] AKAW2_70545S COG:G; EggNog:ENOG410PF8Z; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690,PF00083; TransMembrane:10 (i67-87o107-125i137-154o160-182i203-219o225-243i277- 295o315-337i346-363o442-464i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_70546S CAZy:GH28; COG:G; EggNog:ENOG410PFRD; InterPro:IPR000743,IPR012334,IPR006626,IPR011050; PFAM:PF00295; SECRETED:SignalP(1-19); go_function: GO:0004650 - polygalacturonase activity [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_70547S CAZy:GH13; COG:G; EggNog:ENOG410PGMM; InterPro:IPR006046,IPR006047,IPR015340,IPR017853, IPR013780,IPR013777; PFAM:PF00128,PF09260; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0004556 - alpha-amylase activity [Evidence IEA]; go_function: GO:0005509 - calcium ion binding [Evidence IEA]; go_function: GO:0043169 - cation binding [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA]; go_process: GO:0016052 - carbohydrate catabolic process [Evidence IEA] AKAW2_70548A COG:I; EggNog:ENOG410PJU0; InterPro:IPR000873,IPR009081,IPR006162,IPR036736, IPR042099,IPR020845; PFAM:PF00501,PF00550; SMCOG1002:AMP-dependent synthetase and ligase; TransMembrane:1 (i232-253o); antiSMASH:Cluster_7.4 AKAW2_70549A COG:S; EggNog:ENOG410PSDH; TransMembrane:6 (o12-33i45-69o89-111i123-146o174-194i206-224o); antiSMASH:Cluster_7.4 AKAW2_70550S COG:S; EggNog:ENOG410PN0R; InterPro:IPR000073,IPR029058; PFAM:PF12697; antiSMASH:Cluster_7.4 AKAW2_70551S COG:S; EggNog:ENOG410PUQD; TransMembrane:6 (i65-83o95-115i136-161o181-203i215-237o257-275i); antiSMASH:Cluster_7.4 AKAW2_70552A COG:T; EggNog:ENOG410PMTX; InterPro:IPR004839,IPR004838,IPR015424,IPR015421, IPR015422; PFAM:PF00155; SMCOG1019:aminotransferase; antiSMASH:Cluster_7.4; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0030170 - pyridoxal phosphate binding [Evidence IEA]; go_process: GO:0009058 - biosynthetic process [Evidence IEA] AKAW2_70553S COG:S; EggNog:ENOG410PTAV; InterPro:IPR011008,IPR009799; PFAM:PF07110; antiSMASH:Cluster_7.4; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA] AKAW2_70554A COG:G; EggNog:ENOG410PG24; InterPro:IPR017853; SECRETED:SignalP(1-18); antiSMASH:Cluster_7.4 AKAW2_70555S COG:S; EggNog:ENOG410Q28M; antiSMASH:Cluster_7.4 AKAW2_70556A COG:Q; EggNog:ENOG410PPD6; InterPro:IPR036291,IPR002347; PFAM:PF13561; SMCOG1001:short-chain dehydrogenase/reductase SDR; antiSMASH:Cluster_7.4; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_70557A COG:C; EggNog:ENOG410PIR1; InterPro:IPR003702,IPR026888,IPR038460,IPR037171; PFAM:PF02550,PF13336; antiSMASH:Cluster_7.4; go_function: GO:0003986 - acetyl-CoA hydrolase activity [Evidence IEA]; go_function: GO:0008775 - acetate CoA-transferase activity [Evidence IEA]; go_process: GO:0006083 - acetate metabolic process [Evidence IEA]; go_process: GO:0019679 - propionate metabolic process, methylcitrate cycle [Evidence IEA] AKAW2_70558A COG:B; EggNog:ENOG410PFTT; InterPro:IPR013194,IPR039774,IPR036600,IPR031693, IPR003822; PFAM:PF16879,PF02671,PF08295; go_function: GO:0003714 - transcription corepressor activity [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_70559A BUSCO:EOG09261MG9; COG:T; EggNog:ENOG410PHQV; InterPro:IPR036322,IPR018067,IPR000009,IPR001680, IPR019775; PFAM:PF00400; go_component: GO:0000159 - protein phosphatase type 2A complex [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_function: GO:0019888 - protein phosphatase regulator activity [Evidence IEA] AKAW2_70560S COG:S; EggNog:ENOG410PY8A AKAW2_70561A COG:C; EggNog:ENOG410PG2C; InterPro:IPR036188,IPR003953,IPR001199,IPR027477, IPR036400,IPR010960; PFAM:PF07992,PF00173,PF01266,PF13450,PF01494, PF00890; go_function: GO:0000104 - succinate dehydrogenase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_70562A InterPro:IPR029063 AKAW2_70564A COG:Q; EggNog:ENOG410PWB7; InterPro:IPR001227,IPR016036,IPR014043,IPR016035; PFAM:PF00698; go_function: GO:0016740 - transferase activity [Evidence IEA] AKAW2_70565A COG:C; EggNog:ENOG410PICX; InterPro:IPR015590,IPR016160,IPR016161,IPR016162, IPR016163; PFAM:PF00171; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0016620 - oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_70566S COG:S; EggNog:ENOG410PXWQ; TransMembrane:7 (o12-31i43-63o83-109i121-143o163-188i200-226o238-258i) AKAW2_70567A COG:O,T; EggNog:ENOG410PI81; InterPro:IPR037754,IPR011990,IPR036388,IPR019585, IPR040134,IPR036390,IPR000717; PFAM:PF10602,PF01399; go_component: GO:0008180 - COP9 signalosome [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_70568S BUSCO:EOG09262NIR; COG:K; EggNog:ENOG410PHE0; InterPro:IPR040504,IPR036388,IPR036390,IPR011039, IPR040450,IPR003196; PFAM:PF02270,PF17683; go_component: GO:0005674 - transcription factor TFIIF complex [Evidence IEA]; go_process: GO:0006366 - transcription by RNA polymerase II [Evidence IEA]; go_process: GO:0006367 - transcription initiation from RNA polymerase II promoter [Evidence IEA] AKAW2_70569S COG:S; EggNog:ENOG410PKGH; InterPro:IPR000571,IPR036855; go_function: GO:0046872 - metal ion binding [Evidence IEA] AKAW2_70570S COG:S; EggNog:ENOG410PKHS; InterPro:IPR004827; PFAM:PF00170,PF03131,PF07716; TransMembrane:1 (o436-453i); go_function: GO:0003700 - DNA-binding transcription factor activity [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_70571A COG:S; EggNog:ENOG410PHQU; InterPro:IPR011990,IPR006597; PFAM:PF08238; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_70572A BUSCO:EOG09264PE5; COG:C; EggNog:ENOG410PJIQ; InterPro:IPR013837,IPR008688; PFAM:PF05405; go_component: GO:0000276 - mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) [Evidence IEA]; go_function: GO:0015078 - proton transmembrane transporter activity [Evidence IEA]; go_process: GO:0015986 - ATP synthesis coupled proton transport [Evidence IEA] AKAW2_70573S BUSCO:EOG09261RWU; COG:J; EggNog:ENOG410PFB4; InterPro:IPR005612,IPR027193; PFAM:PF03914; TransMembrane:3 (o324-342i376-395o401-421i); go_process: GO:0042254 - ribosome biogenesis [Evidence IEA] AKAW2_70574A COG:S; EggNog:ENOG410Q24R; SECRETED:SignalP(1-23) AKAW2_70575S COG:S; EggNog:ENOG410PSZ4; InterPro:IPR018466; PFAM:PF10342; SECRETED:SignalP(1-22); TransMembrane:1 (n6-17c25/26o195-216i) AKAW2_70576S COG:S; EggNog:ENOG410PWJW AKAW2_70577S COG:S; EggNog:ENOG410PTJC AKAW2_70578A BUSCO:EOG09260SR2; COG:K,L; EggNog:ENOG410PIBN; InterPro:IPR016024,IPR011989,IPR039920,IPR029240, IPR024687; PFAM:PF12460,PF14500; go_process: GO:0097428 - protein maturation by iron-sulfur cluster transfer [Evidence IEA] AKAW2_70579S COG:S; EggNog:ENOG410PPP5; InterPro:IPR036378,IPR000782,IPR040200 AKAW2_70580A BUSCO:EOG0926431P; COG:S; EggNog:ENOG410PKAD; InterPro:IPR008568,IPR002809; PFAM:PF01956; TransMembrane:3 (o16-34i129-150o181-200i); go_component: GO:0016020 - membrane [Evidence IEA] AKAW2_70581S BUSCO:EOG09265B95; COG:U; EggNog:ENOG410PQTS; InterPro:IPR009582; PFAM:PF06703; TransMembrane:2 (i47-65o77-100i); go_component: GO:0005787 - signal peptidase complex [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_process: GO:0006465 - signal peptide processing [Evidence IEA] AKAW2_70582A BUSCO:EOG09263RW3; COG:H; EggNog:ENOG410PHTA; InterPro:IPR020631,IPR000672,IPR036291,IPR035812, IPR020630; PFAM:PF00763; go_function: GO:0004488 - methylenetetrahydrofolate dehydrogenase (NADP+) activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_70583A COG:C; EggNog:ENOG410Q7XU; InterPro:IPR027417,IPR023366,IPR005294,IPR000793, IPR038376,IPR036121,IPR004100,IPR020003,IPR033732, IPR000194; PFAM:PF00006,PF00306,PF02874; go_component: GO:0045261 - proton-transporting ATP synthase complex, catalytic core F(1) [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0032559 - adenyl ribonucleotide binding [Evidence IEA]; go_function: GO:0046933 - proton-transporting ATP synthase activity, rotational mechanism [Evidence IEA]; go_process: GO:0015986 - ATP synthesis coupled proton transport [Evidence IEA]; go_process: GO:0046034 - ATP metabolic process [Evidence IEA]; go_process: GO:1902600 - proton transmembrane transport [Evidence IEA] AKAW2_70584A COG:S; EggNog:ENOG410PRCX; InterPro:IPR009305; PFAM:PF06127; TransMembrane:5 (o20-40i61-77o83-100i107-129o141-161i) AKAW2_70585S BUSCO:EOG09264RW6; COG:K; EggNog:ENOG410PG7B; InterPro:IPR036898,IPR003029,IPR012340,IPR005576; PFAM:PF03876,PF00575; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA] AKAW2_70586S COG:S; EggNog:ENOG410PHI7 AKAW2_70587A COG:J; EggNog:ENOG410PISF; InterPro:IPR012337,IPR032474,IPR036397,IPR032472, IPR014811,IPR036085,IPR003100,IPR003165; PFAM:PF02171,PF16486,PF08699,PF16488; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_70588S COG:S; EggNog:ENOG410PKDV; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_70589S COG:K; EggNog:ENOG410PP02; InterPro:IPR000504,IPR012677,IPR035979; PFAM:PF00076; SECRETED:SignalP(1-23); go_function: GO:0003676 - nucleic acid binding [Evidence IEA] AKAW2_70590S COG:U; EggNog:ENOG410PFAB; InterPro:IPR011990,IPR024111,IPR019734,IPR013026; PFAM:PF07719,PF13181,PF00515,PF13176,PF13414, PF07720,PF13432; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_70591S COG:E,H; EggNog:ENOG410PHRM; InterPro:IPR012001,IPR012000,IPR011766,IPR029061, IPR029035; PFAM:PF02775,PF02776,PF00205; go_function: GO:0000287 - magnesium ion binding [Evidence IEA]; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0030976 - thiamine pyrophosphate binding [Evidence IEA] AKAW2_70592A COG:I,J,T; EggNog:ENOG410PUE9; InterPro:IPR023631,IPR036928 AKAW2_70593A COG:I,J,T; EggNog:ENOG410PFMP; InterPro:IPR023631,IPR036928,IPR020556; PFAM:PF01425 AKAW2_70594A COG:S; EggNog:ENOG410PISG; InterPro:IPR029063,IPR003788,IPR038375; PFAM:PF02636 AKAW2_70595S COG:E; EggNog:ENOG410PIEF; InterPro:IPR036052,IPR001926; PFAM:PF00291; TransMembrane:1 (o6-27i) AKAW2_70596A COG:S; EggNog:ENOG410PSQT; InterPro:IPR009072,IPR001005,IPR018465; PFAM:PF10384; go_component: GO:0005634 - nucleus [Evidence IEA]; go_function: GO:0042393 - histone binding [Evidence IEA]; go_function: GO:0046982 - protein heterodimerization activity [Evidence IEA] AKAW2_70597S BUSCO:EOG09262FJB; COG:T; EggNog:ENOG410PI06; InterPro:IPR041691,IPR007243,IPR038274,IPR040455; PFAM:PF17675,PF04111; go_process: GO:0006914 - autophagy [Evidence IEA] AKAW2_70600S COG:S; EggNog:ENOG410PTYT; InterPro:IPR025676; PFAM:PF14420 AKAW2_70601A COG:U; EggNog:ENOG410PFZY; InterPro:IPR035463,IPR036028,IPR001452,IPR007223; PFAM:PF04088,PF00018,PF07653; TransMembrane:1 (o274-296i); go_component: GO:0005777 - peroxisome [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0016560 - protein import into peroxisome matrix, docking [Evidence IEA] AKAW2_70602A BUSCO:EOG09261JR0; COG:O; EggNog:ENOG410PG36; InterPro:IPR037192,IPR007266; PFAM:PF04137; SECRETED:SignalP(1-21); go_component: GO:0005783 - endoplasmic reticulum [Evidence IEA]; go_function: GO:0003756 - protein disulfide isomerase activity [Evidence IEA]; go_function: GO:0016671 - oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_70603A COG:S; EggNog:ENOG410PH2I; InterPro:IPR013226 AKAW2_70604S COG:A; EggNog:ENOG410PQ32; InterPro:IPR027521; PFAM:PF09749; go_function: GO:0004518 - nuclease activity [Evidence IEA]; go_process: GO:0034477 - U6 snRNA 3'-end processing [Evidence IEA] AKAW2_70605S COG:S; EggNog:ENOG410PRXT; InterPro:IPR024526; PFAM:PF12720 AKAW2_70606A COG:G; EggNog:ENOG410PFJG; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i43-62o68-86i98-118o124-143i155-177o189-209i239-262o274- 292i304-323o329-350i362-380o392-411i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_70607S COG:E; EggNog:ENOG410PHHD; InterPro:IPR013057; PFAM:PF01490; TransMembrane:11 (i66-85o91-112i140-163o175-192i199-222o242-261i273- 294o314-333i354-375o387-408i420-443o) AKAW2_70608A COG:S; EggNog:ENOG410PKC1; InterPro:IPR038988,IPR029184; PFAM:PF15460; go_component: GO:0033255 - SAS acetyltransferase complex [Evidence IEA]; go_process: GO:0016573 - histone acetylation [Evidence IEA] AKAW2_70609S COG:E; EggNog:ENOG410PKFF; InterPro:IPR002220,IPR013785; PFAM:PF00701; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0016829 - lyase activity [Evidence IEA] AKAW2_70610A COG:S; EggNog:ENOG410PJGH; InterPro:IPR008979,IPR029058,IPR005674,IPR013736, IPR000383; PFAM:PF02129,PF08530; go_function: GO:0008239 - dipeptidyl-peptidase activity [Evidence IEA]; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_70612A COG:S; EggNog:ENOG410PRWR; InterPro:IPR021765; PFAM:PF11807; TransMembrane:1 (i12-34o); go_process: GO:0043386 - mycotoxin biosynthetic process [Evidence IEA] AKAW2_70613S COG:S; EggNog:ENOG410PHHG; InterPro:IPR013087 AKAW2_70614S COG:F; EggNog:ENOG410PHNY; InterPro:IPR043171,IPR019200,IPR036265,IPR009163; PFAM:PF09830; go_function: GO:0003877 - ATP adenylyltransferase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0009117 - nucleotide metabolic process [Evidence IEA] AKAW2_70615A COG:S; EggNog:ENOG410PRFC AKAW2_70616A COG:S; EggNog:ENOG410PNCS; InterPro:IPR010640; PFAM:PF06772; TransMembrane:12 (i58-77o83-103i115-133o145-171i183-204o210-229i250- 269o281-301i322-342o468-488i500-518o524-547i) AKAW2_70617A COG:S; EggNog:ENOG410PPP3 AKAW2_70618S COG:A; EggNog:ENOG410PQQQ; InterPro:IPR034098,IPR010920,IPR001163; PFAM:PF01423; go_component: GO:0005681 - spliceosomal complex [Evidence IEA]; go_process: GO:0000387 - spliceosomal snRNP assembly [Evidence IEA] AKAW2_70619A BUSCO:EOG09260289; COG:K; EggNog:ENOG410PFBT; InterPro:IPR042097,IPR037813; go_component: GO:0005669 - transcription factor TFIID complex [Evidence IEA] AKAW2_70620S COG:I; EggNog:ENOG410PK7Y; InterPro:IPR014472,IPR000462,IPR043130; PFAM:PF01066; TransMembrane:8 (i47-70o90-108i189-208o230-253i265-284o296-316i328- 346o358-379i); go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0016780 - phosphotransferase activity, for other substituted phosphate groups [Evidence IEA]; go_process: GO:0008654 - phospholipid biosynthetic process [Evidence IEA] AKAW2_70621A COG:S; EggNog:ENOG410Q27X; InterPro:IPR036864,IPR021858,IPR001138; PFAM:PF00172; TransMembrane:1 (i189-206o); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_70622S COG:E; EggNog:ENOG410PG14; InterPro:IPR002293; PFAM:PF00324,PF13520; SECRETED:SignalP(1-31); TransMembrane:12 (i46-70o82-106i127-151o171-191i203-222o242-259i280- 304o331-349i385-404o416-434i446-470o482-503i); go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_70623A COG:S; EggNog:ENOG410PQH4; InterPro:IPR028648,IPR001683,IPR036871,IPR037917; PFAM:PF00787; go_function: GO:0032266 - phosphatidylinositol-3-phosphate binding [Evidence IEA]; go_function: GO:0035091 - phosphatidylinositol binding [Evidence IEA] AKAW2_70624S COG:S; EggNog:ENOG410PR46; SECRETED:SignalP(1-19); TransMembrane:1 (n7-18c24/25o171-188i) AKAW2_70627S COG:O,T; EggNog:ENOG410PGAD; InterPro:IPR019585,IPR036390,IPR033008,IPR000717; PFAM:PF10602,PF01399; go_component: GO:0008180 - COP9 signalosome [Evidence IEA]; go_process: GO:0000338 - protein deneddylation [Evidence IEA] AKAW2_70628A SECRETED:SignalP(1-20) AKAW2_70629A COG:G; EggNog:ENOG410PJGR; InterPro:IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i16-42o54-73i85-103o115-139i160-180o200-219i276-299o330- 352i364-384o396-424i489-509o521-543i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_70630S COG:O; EggNog:ENOG410PGY0; InterPro:IPR001841,IPR024766,IPR013083; PFAM:PF00097,PF13445,PF13639,PF12678; TransMembrane:5 (n3-14c19/20o43-60i98-118o138-160i172-195o276-297i); go_function: GO:0008270 - zinc ion binding [Evidence IEA] AKAW2_70631S COG:S; EggNog:ENOG410PHVY; InterPro:IPR021838; PFAM:PF11913; SECRETED:SignalP(1-28) AKAW2_70632S COG:S; EggNog:ENOG410PPIF AKAW2_70633A BUSCO:EOG09264THP; COG:J; EggNog:ENOG410PG4W; InterPro:IPR016195,IPR002738; PFAM:PF01876; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0004526 - ribonuclease P activity [Evidence IEA]; go_process: GO:0008033 - tRNA processing [Evidence IEA] AKAW2_70634S COG:D,K,T; EggNog:ENOG410PI5T; InterPro:IPR017441,IPR008271,IPR000719,IPR011009; PFAM:PF07714,PF00069; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_70635S COG:J; EggNog:ENOG410PI3F; InterPro:IPR013155,IPR009080,IPR001412,IPR033705, IPR014729,IPR009008,IPR002300,IPR002303; PFAM:PF08264,PF00133; go_function: GO:0000166 - nucleotide binding [Evidence IEA]; go_function: GO:0002161 - aminoacyl-tRNA editing activity [Evidence IEA]; go_function: GO:0004812 - aminoacyl-tRNA ligase activity [Evidence IEA]; go_function: GO:0004832 - valine-tRNA ligase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006418 - tRNA aminoacylation for protein translation [Evidence IEA]; go_process: GO:0006438 - valyl-tRNA aminoacylation [Evidence IEA] AKAW2_70636S BUSCO:EOG09263EBB; COG:J; EggNog:ENOG410PFUF; InterPro:IPR007109,IPR039770; PFAM:PF04427; go_function: GO:0019843 - rRNA binding [Evidence IEA]; go_process: GO:0000027 - ribosomal large subunit assembly [Evidence IEA]; go_process: GO:0000470 - maturation of LSU-rRNA [Evidence IEA] AKAW2_70637S COG:U; EggNog:ENOG410PN4H; InterPro:IPR019531; PFAM:PF02466; TransMembrane:2 (i125-142o165-183i) AKAW2_70638A COG:S; EggNog:ENOG410PMMC; InterPro:IPR036864,IPR001138; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_70639S COG:Q; EggNog:ENOG410PUEJ; InterPro:IPR001128,IPR017972,IPR002401,IPR036396; TransMembrane:1 (o6-26i); go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_70640A COG:T; EggNog:ENOG410PKHA; InterPro:IPR019819,IPR019826,IPR002018,IPR029058; MEROPS:MER0033188; PFAM:PF00135; SECRETED:SignalP(1-21) AKAW2_70641S COG:G; EggNog:ENOG410PUF6; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:14 (i70-95o107-126i138-158o170-188i195-214o226-246i258- 281o293-311i332-349o369-389i396-414o426-448i460-483o543- 561i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_70642A CAZy:GH76; COG:G; EggNog:ENOG410PFRH; InterPro:IPR014480,IPR008928,IPR005198; PFAM:PF03663; SECRETED:SignalP(1-22); TransMembrane:1 (n9-18c22/23o432-454i); go_function: GO:0008496 - mannan endo-1,6-alpha-mannosidase activity [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA]; go_process: GO:0016052 - carbohydrate catabolic process [Evidence IEA] AKAW2_70643S COG:F; EggNog:ENOG410PQPV; InterPro:IPR007247,IPR011051,IPR024060; PFAM:PF04115; go_function: GO:0004848 - ureidoglycolate hydrolase activity [Evidence IEA]; go_function: GO:0050385 - ureidoglycolate lyase activity [Evidence IEA]; go_process: GO:0000256 - allantoin catabolic process [Evidence IEA] AKAW2_70644A COG:L; EggNog:ENOG410PFR9; InterPro:IPR036187,IPR036678,IPR027417,IPR017261, IPR016151,IPR000432,IPR007695,IPR007696,IPR007860; PFAM:PF05192,PF00488,PF01624; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0030983 - mismatched DNA binding [Evidence IEA]; go_process: GO:0006298 - mismatch repair [Evidence IEA] AKAW2_70645S COG:A; EggNog:ENOG410PGAG; InterPro:IPR014756,IPR004179,IPR041094,IPR027417, IPR003593,IPR035892,IPR001650,IPR036390,IPR014001, IPR011545; PFAM:PF18149,PF02889,PF00271,PF04851,PF00270; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA] AKAW2_70646A COG:S; EggNog:ENOG410PT3H; InterPro:IPR036236,IPR036864,IPR007219,IPR013087, IPR001138; PFAM:PF00172,PF04082; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_70647A COG:C,H; EggNog:ENOG410PV0D; InterPro:IPR036188,IPR002938; PFAM:PF01494,PF07992; SECRETED:SignalP(1-18); go_function: GO:0071949 - FAD binding [Evidence IEA] AKAW2_70648S COG:O; EggNog:ENOG410PJF7; InterPro:IPR001375,IPR029058; MEROPS:MER0000263; PFAM:PF00326; go_function: GO:0008236 - serine-type peptidase activity [Evidence IEA]; go_process: GO:0006508 - proteolysis [Evidence IEA] AKAW2_70649A COG:U; EggNog:ENOG410QDYK; InterPro:IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i58-81o101-118i125-143o149-166i186-208o214-233i310- 333o353-378i399-418o424-452i464-482o494-515i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_70650A BUSCO:EOG09263OAE; COG:T; EggNog:ENOG410PM2Q; InterPro:IPR017441,IPR008271,IPR000719,IPR011009; PFAM:PF07714,PF00069; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_70652S COG:Z; EggNog:ENOG410PJEP; InterPro:IPR032108,IPR036859,IPR000938; PFAM:PF16641,PF01302 AKAW2_70653A COG:E; EggNog:ENOG410PNFY; InterPro:IPR014710,IPR011051,IPR010329; PFAM:PF06052; go_function: GO:0000334 - 3-hydroxyanthranilate 3,4-dioxygenase activity [Evidence IEA]; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_70654S BUSCO:EOG0926307V; COG:A; EggNog:ENOG410PH5X; InterPro:IPR037136,IPR000228,IPR036553,IPR013791, IPR013792,IPR023797,IPR016443; PFAM:PF01137,PF05189; go_component: GO:0005730 - nucleolus [Evidence IEA]; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_process: GO:0006396 - RNA processing [Evidence IEA]; go_process: GO:0042254 - ribosome biogenesis [Evidence IEA] AKAW2_70655S TransMembrane:1 (o45-63i) AKAW2_70656A COG:S; EggNog:ENOG410PIYD; InterPro:IPR036291,IPR008030; PFAM:PF05368 AKAW2_70658A COG:G; EggNog:ENOG410PGJK; InterPro:IPR004547,IPR037171; go_function: GO:0004342 - glucosamine-6-phosphate deaminase activity [Evidence IEA]; go_process: GO:0006044 - N-acetylglucosamine metabolic process [Evidence IEA] AKAW2_70659A COG:P; EggNog:ENOG410PFHW; InterPro:IPR004695,IPR038665,IPR030185; PFAM:PF03595; TransMembrane:10 (i61-80o92-117i129-148o168-189i201-221o227-249i270- 291o311-336i348-368o380-401i); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0015140 - malate transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA]; go_process: GO:0071423 - malate transmembrane transport [Evidence IEA] AKAW2_70660A COG:S; EggNog:ENOG410PXHA AKAW2_70661A BUSCO:EOG09264XM2; COG:O; EggNog:ENOG410PNVH; InterPro:IPR004640,IPR001623,IPR009073,IPR036869, IPR036386; PFAM:PF07743; go_function: GO:0001671 - ATPase activator activity [Evidence IEA]; go_function: GO:0051087 - chaperone binding [Evidence IEA]; go_process: GO:0051259 - protein complex oligomerization [Evidence IEA]; go_process: GO:0097428 - protein maturation by iron-sulfur cluster transfer [Evidence IEA] AKAW2_70662A BUSCO:EOG09262CXO; COG:A; EggNog:ENOG410PGT6; InterPro:IPR001680,IPR014906,IPR036322,IPR015943, IPR036285,IPR019775,IPR020472,IPR017986; PFAM:PF08799,PF00400; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_70663S BUSCO:EOG09263I4U; COG:T; EggNog:ENOG410PJPG; InterPro:IPR036457,IPR039123,IPR001932; PFAM:PF07228,PF13672; go_function: GO:0016791 - phosphatase activity [Evidence IEA] AKAW2_70664A COG:S; EggNog:ENOG410PJEG; InterPro:IPR000313; PFAM:PF00855 AKAW2_70665A COG:S; EggNog:ENOG410PJNV; InterPro:IPR026841; TransMembrane:7 (o6-23i117-133o190-210i245-263o317-336i357-379o385-406i) AKAW2_70666S COG:S; EggNog:ENOG410PJ3F; InterPro:IPR003830,IPR036112,IPR013785; PFAM:PF02679; go_function: GO:0003824 - catalytic activity [Evidence IEA] AKAW2_70667S COG:S; EggNog:ENOG410PM76; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; TransMembrane:2 (o440-461i517-537o); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_70668A BUSCO:EOG09261404; COG:Z; EggNog:ENOG410PJ25; InterPro:IPR007131,IPR013182,IPR038159,IPR035821, IPR035800,IPR029922,IPR001452,IPR036028,IPR013761; PFAM:PF07653,PF00018,PF08226,PF14604,PF03983; go_function: GO:0005515 - protein binding [Evidence IEA]; go_function: GO:0008092 - cytoskeletal protein binding [Evidence IEA]; go_function: GO:0030674 - protein-macromolecule adaptor activity [Evidence IEA]; go_function: GO:0042802 - identical protein binding [Evidence IEA]; go_function: GO:0043130 - ubiquitin binding [Evidence IEA]; go_process: GO:0006897 - endocytosis [Evidence IEA] AKAW2_70669A BUSCO:EOG09264C3V; COG:O; EggNog:ENOG410PK6W; InterPro:IPR009011,IPR012913; PFAM:PF07915; SECRETED:SignalP(1-23) AKAW2_70670S COG:S; EggNog:ENOG410PH6B; InterPro:IPR008778,IPR003829,IPR012093,IPR014710, IPR011051; PFAM:PF05726,PF02678 AKAW2_70671A CAZy:GT39; COG:O; EggNog:ENOG410PGU4; InterPro:IPR036300,IPR027005,IPR016093,IPR003342, IPR032421; PFAM:PF16192,PF02815,PF02366; TransMembrane:11 (i40-59o94-114i126-149o155-172i179-201o221-249i270- 289o592-613i634-653o665-685i726-747o); go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0000030 - mannosyltransferase activity [Evidence IEA]; go_process: GO:0006493 - protein O-linked glycosylation [Evidence IEA] AKAW2_70672A COG:S; EggNog:ENOG410PMH6 AKAW2_70673S COG:G; EggNog:ENOG410PK0R; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690,PF00083; TransMembrane:12 (i48-67o87-109i116-136o142-164i176-193o213-232i283- 307o327-344i351-371o377-397i409-430o442-466i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_70675A COG:S; EggNog:ENOG410PQ74; TransMembrane:7 (o15-36i48-70o105-124i131-160o180-199i211-230o250-274i) AKAW2_70677S COG:S; EggNog:ENOG410PWT0; InterPro:IPR001077,IPR036388,IPR016461,IPR029063, IPR036390; PFAM:PF00891; go_function: GO:0008168 - methyltransferase activity [Evidence IEA]; go_function: GO:0008171 - O-methyltransferase activity [Evidence IEA] AKAW2_70676A COG:Z; EggNog:ENOG410PH9X; InterPro:IPR015943,IPR001680,IPR036322,IPR017986; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_70678S COG:S; EggNog:ENOG410PS6S; InterPro:IPR008386; PFAM:PF05680; go_component: GO:0000276 - mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) [Evidence IEA]; go_function: GO:0015078 - proton transmembrane transporter activity [Evidence IEA]; go_process: GO:0015986 - ATP synthesis coupled proton transport [Evidence IEA] AKAW2_70679A COG:S; EggNog:ENOG410PU36; InterPro:IPR033464; PFAM:PF10075 AKAW2_70680S BUSCO:EOG09260TVA; CAZy:GT66; COG:O; EggNog:ENOG410PFZR; InterPro:IPR003674; PFAM:PF02516; TransMembrane:13 (i21-43o91-107i119-138o144-163i175-191o211-234i246- 267o273-291i303-329o364-384i391-409o415-437i478-497o); go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0004576 - oligosaccharyl transferase activity [Evidence IEA]; go_process: GO:0006486 - protein glycosylation [Evidence IEA] AKAW2_70681A BUSCO:EOG09265KSE; COG:S; EggNog:ENOG410PSRB; InterPro:IPR018628,IPR041752; TransMembrane:1 (i33-51o); go_process: GO:0033617 - mitochondrial cytochrome c oxidase assembly [Evidence IEA] AKAW2_70682A TransMembrane:3 (o20-43i50-69o81-101i) AKAW2_70683S COG:S; EggNog:ENOG410PY96; InterPro:IPR023213,IPR003480; PFAM:PF02458; go_function: GO:0016747 - transferase activity, transferring acyl groups other than amino-acyl groups [Evidence IEA] AKAW2_70684S BUSCO:EOG09260C2V; COG:A; EggNog:ENOG410QDUP; InterPro:IPR011989,IPR032460,IPR021850; PFAM:PF11935 AKAW2_70685A COG:S; EggNog:ENOG410PN9F; InterPro:IPR013907; PFAM:PF08598 AKAW2_70686S BUSCO:EOG09264IQ7; COG:A; EggNog:ENOG410PJZ3; InterPro:IPR000504,IPR012677,IPR034777,IPR035979; PFAM:PF00076; go_function: GO:0003676 - nucleic acid binding [Evidence IEA] AKAW2_70687S COG:S; EggNog:ENOG410PQNW AKAW2_70688S COG:S; EggNog:ENOG410PNWR; InterPro:IPR036188,IPR023753; PFAM:PF07992; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_70689S COG:S; EggNog:ENOG410PSWU; InterPro:IPR018531,IPR034660; PFAM:PF09351 AKAW2_70690A COG:S; EggNog:ENOG410PX74; TransMembrane:2 (o166-187i199-225o) AKAW2_70691S COG:T; EggNog:ENOG410PW7G; InterPro:IPR000719,IPR011009; PFAM:PF07714,PF00069; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_70692A COG:S; EggNog:ENOG410PYSY; InterPro:IPR018466; PFAM:PF10342; SECRETED:SignalP(1-18) AKAW2_70693A COG:S; EggNog:ENOG410PQ5K; InterPro:IPR019496,IPR000571,IPR036855; PFAM:PF10453,PF00642,PF18044; go_function: GO:0046872 - metal ion binding [Evidence IEA] AKAW2_70694S COG:K; EggNog:ENOG410PNFC; InterPro:IPR005576,IPR036898,IPR013238,IPR012340; PFAM:PF03876,PF08292; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA] AKAW2_70695S COG:E; EggNog:ENOG410PGYK; InterPro:IPR000277,IPR015424,IPR015421,IPR015422; PFAM:PF01053; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0030170 - pyridoxal phosphate binding [Evidence IEA]; go_process: GO:0019346 - transsulfuration [Evidence IEA] AKAW2_70696S COG:A; EggNog:ENOG410PNYI; InterPro:IPR019410 AKAW2_70697A COG:S; EggNog:ENOG410PS0D; InterPro:IPR034444; go_component: GO:0005739 - mitochondrion [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_70698S COG:S; EggNog:ENOG410PTS5; InterPro:IPR038799 AKAW2_70699S COG:S; EggNog:ENOG410PHGM; InterPro:IPR013087 AKAW2_70700S COG:S; EggNog:ENOG410PITN; InterPro:IPR013087 AKAW2_70701A COG:S; EggNog:ENOG410PS1B; TransMembrane:1 (i50-69o) AKAW2_70702S BUSCO:EOG092606O3; COG:O; EggNog:ENOG410PFX7; InterPro:IPR036427,IPR041569,IPR003959,IPR027417, IPR003593,IPR003960; PFAM:PF00004,PF17862,PF07724; go_function: GO:0005515 - protein binding [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA] AKAW2_70703S BUSCO:EOG09264TQ5; COG:U; EggNog:ENOG410PN7T; InterPro:IPR018624; PFAM:PF09802; TransMembrane:1 (o6-28i); go_component: GO:0031207 - Sec62/Sec63 complex [Evidence IEA]; go_process: GO:0031204 - posttranslational protein targeting to membrane, translocation [Evidence IEA] AKAW2_70704A COG:S; EggNog:ENOG410PQ0K; InterPro:IPR002885 AKAW2_70705S COG:L; EggNog:ENOG410PH3F; InterPro:IPR040855,IPR020795; go_component: GO:0005664 - nuclear origin of replication recognition complex [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_process: GO:0006260 - DNA replication [Evidence IEA] AKAW2_70706A COG:S; EggNog:ENOG410PPF0 AKAW2_70707S BUSCO:EOG092620IA; COG:J; EggNog:ENOG410PH17; InterPro:IPR007276; PFAM:PF04147; go_component: GO:0032040 - small-subunit processome [Evidence IEA] AKAW2_70708A CAZy:CE10; COG:T; EggNog:ENOG410PM0V; InterPro:IPR019819,IPR019826,IPR002018,IPR029058; MEROPS:MER0033235; PFAM:PF00135; SECRETED:SignalP(1-18) AKAW2_70709S COG:S; EggNog:ENOG410PNC7; InterPro:IPR000467,IPR039249,IPR025239; PFAM:PF13821,PF01585; go_function: GO:0003676 - nucleic acid binding [Evidence IEA] AKAW2_70710A COG:S; EggNog:ENOG410PTFA AKAW2_70712A BUSCO:EOG09263RF8; COG:S; EggNog:ENOG410PKFJ; InterPro:IPR039301 AKAW2_70713S COG:S; EggNog:ENOG410PNMC AKAW2_70714S COG:S; EggNog:ENOG410PR64; SECRETED:SignalP(1-26); TransMembrane:1 (n10-21c26/27o123-141i) AKAW2_70715S COG:G; EggNog:ENOG410PIQ5; InterPro:IPR020846,IPR001958,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:11 (o53-75i87-110o116-136i148-167o187-211i288-307o346- 368i375-397o403-429i441-464o476-495i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_70716S COG:S; EggNog:ENOG410PM6K; InterPro:IPR039915,IPR024312; PFAM:PF12709; go_process: GO:0007052 - mitotic spindle organization [Evidence IEA] AKAW2_70717A InterPro:IPR036249,IPR013766; PFAM:PF00085 AKAW2_70718S COG:K; EggNog:ENOG410PH1M; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF04082; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_70719S COG:E,O; EggNog:ENOG410PKAW; InterPro:IPR018202,IPR001563,IPR033124,IPR029058; MEROPS:MER0016549; PFAM:PF00450; SECRETED:SignalP(1-18); go_function: GO:0004185 - serine-type carboxypeptidase activity [Evidence IEA]; go_process: GO:0006508 - proteolysis [Evidence IEA] AKAW2_70720A COG:S; EggNog:ENOG410PGEQ; InterPro:IPR011701,IPR036259; PFAM:PF07690,PF05978; TransMembrane:10 (i59-76o96-112i119-138o144-169i181-203o215-234i271- 289o309-327i339-358o378-402i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_70721S CAZy:CE9; COG:G; EggNog:ENOG410PGIH; InterPro:IPR006680,IPR003764,IPR011059,IPR032466; MEROPS:MER0033184; PFAM:PF01979; go_function: GO:0008448 - N-acetylglucosamine-6-phosphate deacetylase activity [Evidence IEA]; go_function: GO:0016787 - hydrolase activity [Evidence IEA]; go_function: GO:0016810 - hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [Evidence IEA]; go_process: GO:0006044 - N-acetylglucosamine metabolic process [Evidence IEA] AKAW2_70722A CAZy:AA3; COG:E; EggNog:ENOG410PHQX; InterPro:IPR012132,IPR036188,IPR027424,IPR000172, IPR007867; PFAM:PF00732,PF05199; TransMembrane:1 (o39-64i); go_function: GO:0016614 - oxidoreductase activity, acting on CH-OH group of donors [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_70723S COG:C; EggNog:ENOG410PHBT; InterPro:IPR015590,IPR029510,IPR016160,IPR016161, IPR016162,IPR016163; PFAM:PF00171; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0016620 - oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_70724A COG:G; EggNog:ENOG410PGJK; InterPro:IPR004547,IPR037171,IPR018321,IPR006148; PFAM:PF01182; go_function: GO:0004342 - glucosamine-6-phosphate deaminase activity [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA]; go_process: GO:0006044 - N-acetylglucosamine metabolic process [Evidence IEA] AKAW2_70725S COG:G; EggNog:ENOG410PJPJ; InterPro:IPR036962,IPR036881,IPR001764,IPR016181, IPR017853,IPR000182; PFAM:PF00583; go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_function: GO:0008080 - N-acetyltransferase activity [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_70726S COG:K; EggNog:ENOG410PJ99; InterPro:IPR008967,IPR037141,IPR024061; PFAM:PF05224; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0003700 - DNA-binding transcription factor activity [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_70728S TransMembrane:3 (i12-33o39-63i84-105o) AKAW2_70727A BUSCO:EOG092604KQ; COG:A; EggNog:ENOG410PFX4; InterPro:IPR015943,IPR018846,IPR004871; PFAM:PF03178,PF10433; go_component: GO:0005634 - nucleus [Evidence IEA]; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_70729S COG:P; EggNog:ENOG410PFTJ; InterPro:IPR006876; TransMembrane:10 (i7-29o41-68i89-119o146-167i188-207o312-334i346-364o376- 404i416-435o501-528i) AKAW2_70730A COG:S; EggNog:ENOG410PSFC AKAW2_70731S COG:S; EggNog:ENOG410PK4D; InterPro:IPR036283,IPR018791; PFAM:PF10186 AKAW2_70732S COG:S; EggNog:ENOG410PK4D AKAW2_70733S COG:P; EggNog:ENOG410PGWS; InterPro:IPR003689; PFAM:PF02535; TransMembrane:8 (o64-86i98-119o139-163i301-321o327-345i365-385o397- 420i441-458o); go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0046873 - metal ion transmembrane transporter activity [Evidence IEA]; go_process: GO:0030001 - metal ion transport [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_70734A COG:I; EggNog:ENOG410PG5V; InterPro:IPR016039,IPR020613,IPR020617,IPR020616, IPR020615,IPR002155; PFAM:PF00108,PF02803; go_function: GO:0016746 - transferase activity, transferring acyl groups [Evidence IEA]; go_function: GO:0016747 - transferase activity, transferring acyl groups other than amino-acyl groups [Evidence IEA] AKAW2_70735S COG:J; EggNog:ENOG410PHCW; InterPro:IPR005517,IPR035655,IPR035647,IPR005225, IPR041095,IPR027417,IPR000640,IPR000795,IPR004161, IPR031950,IPR020568,IPR044121,IPR014721,IPR009000; PFAM:PF00679,PF14492,PF03764,PF00009,PF03144, PF01926; go_function: GO:0003924 - GTPase activity [Evidence IEA]; go_function: GO:0005525 - GTP binding [Evidence IEA] AKAW2_70736A BUSCO:EOG09264O3B; COG:S; EggNog:ENOG410PN06; InterPro:IPR002744,IPR034904,IPR039796; PFAM:PF01883; go_process: GO:0106035 - protein maturation by [4Fe-4S] cluster transfer [Evidence IEA] AKAW2_70737S COG:S; EggNog:ENOG410PJQ2; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_70738S COG:S; EggNog:ENOG410PY51 AKAW2_70739A COG:J; EggNog:ENOG410PP0A; InterPro:IPR023584,IPR002661,IPR036191; PFAM:PF01765; go_process: GO:0006412 - translation [Evidence IEA] AKAW2_70740A BUSCO:EOG092617RN; COG:O; EggNog:ENOG410PIHJ; InterPro:IPR018181,IPR029047,IPR029048,IPR013126, IPR043129; PFAM:PF00012,PF06723 AKAW2_70741S COG:D; EggNog:ENOG410PNWC; InterPro:IPR036858,IPR000789; PFAM:PF01111; go_function: GO:0016538 - cyclin-dependent protein serine/threonine kinase regulator activity [Evidence IEA] AKAW2_70742A COG:S; EggNog:ENOG410PN9U; InterPro:IPR036249,IPR012336; PFAM:PF13462 AKAW2_70743A COG:S; EggNog:ENOG410PQ43; TransMembrane:1 (i43-63o) AKAW2_70744A COG:O; EggNog:ENOG410PG37; InterPro:IPR001841,IPR013083; PFAM:PF17123,PF13923,PF00097,PF13445,PF13639; TransMembrane:1 (o31-56i) AKAW2_70745S COG:O; EggNog:ENOG410PN4Y; InterPro:IPR024936,IPR029000,IPR020892,IPR002130; PFAM:PF00160; go_function: GO:0003755 - peptidyl-prolyl cis-trans isomerase activity [Evidence IEA]; go_process: GO:0000413 - protein peptidyl-prolyl isomerization [Evidence IEA]; go_process: GO:0006457 - protein folding [Evidence IEA] AKAW2_70746A BUSCO:EOG09260HPO; COG:J; EggNog:ENOG410PHII; InterPro:IPR023033,IPR003156,IPR018162,IPR018163, IPR018164,IPR018165,IPR002318,IPR012947,IPR009000; PFAM:PF07973,PF01411,PF02272; go_component: GO:0005737 - cytoplasm [Evidence IEA]; go_function: GO:0000166 - nucleotide binding [Evidence IEA]; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0004812 - aminoacyl-tRNA ligase activity [Evidence IEA]; go_function: GO:0004813 - alanine-tRNA ligase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006419 - alanyl-tRNA aminoacylation [Evidence IEA]; go_process: GO:0043039 - tRNA aminoacylation [Evidence IEA] AKAW2_70747S COG:S; EggNog:ENOG410PSUU AKAW2_70748A COG:J; EggNog:ENOG410PGZY; InterPro:IPR027500,IPR001593,IPR018281; PFAM:PF01015; go_component: GO:0005840 - ribosome [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_process: GO:0006412 - translation [Evidence IEA] AKAW2_70749S BUSCO:EOG09265KPR; COG:K; EggNog:ENOG410PQMN; InterPro:IPR007808,IPR038567; PFAM:PF05129 AKAW2_70750A COG:F; EggNog:ENOG410PF9P; InterPro:IPR029057,IPR000836; PFAM:PF14681; go_process: GO:0009116 - nucleoside metabolic process [Evidence IEA] AKAW2_70751S COG:S; EggNog:ENOG410PMSV; InterPro:IPR016024,IPR011989,IPR022771; PFAM:PF07814; TransMembrane:1 (o692-710i) AKAW2_70752S COG:S; EggNog:ENOG410PJZE; InterPro:IPR005225,IPR001806,IPR027417,IPR020849; PFAM:PF00025,PF08477,PF00071,PF01926; go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0003924 - GTPase activity [Evidence IEA]; go_function: GO:0005525 - GTP binding [Evidence IEA]; go_process: GO:0007165 - signal transduction [Evidence IEA] AKAW2_70753S COG:J; EggNog:ENOG410PFEB; InterPro:IPR006195,IPR015866,IPR042103,IPR010978, IPR033729,IPR002317,IPR002314; PFAM:PF02403,PF00587; go_function: GO:0000166 - nucleotide binding [Evidence IEA]; go_function: GO:0004812 - aminoacyl-tRNA ligase activity [Evidence IEA]; go_function: GO:0004828 - serine-tRNA ligase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006418 - tRNA aminoacylation for protein translation [Evidence IEA]; go_process: GO:0006434 - seryl-tRNA aminoacylation [Evidence IEA] AKAW2_70754S BUSCO:EOG09262CO6; COG:E; EggNog:ENOG410PFGT; InterPro:IPR006140,IPR036291,IPR002912,IPR006139, IPR029753,IPR029752; PFAM:PF00389,PF02826; go_function: GO:0016616 - oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Evidence IEA]; go_function: GO:0051287 - NAD binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_70755A COG:D; EggNog:ENOG410PHPD; InterPro:IPR017441,IPR008271,IPR000719,IPR011009; PFAM:PF07714,PF00069; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_70756A COG:P; EggNog:ENOG410PH07; InterPro:IPR018303,IPR023298,IPR023299,IPR001757, IPR036412,IPR008250,IPR006544; PFAM:PF00122,PF00702,PF12409; TransMembrane:11 (o172-192i321-343o349-369i533-557o569-590i1073-1091o1097- 1116i1137-1156o1184-1203i1215-1232o1252-1269i); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0000166 - nucleotide binding [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA]; go_process: GO:0006812 - cation transport [Evidence IEA] AKAW2_70757S BUSCO:EOG09263ULA; COG:B,D; EggNog:ENOG410PH0J; InterPro:IPR037231,IPR002164; PFAM:PF00956; go_component: GO:0005634 - nucleus [Evidence IEA]; go_process: GO:0006334 - nucleosome assembly [Evidence IEA] AKAW2_70758S COG:Z; EggNog:ENOG410PI8B; InterPro:IPR008989,IPR000048,IPR004009,IPR036961, IPR001609,IPR027417,IPR036103,IPR002710; PFAM:PF01843,PF00612,PF00063; go_component: GO:0016459 - myosin complex [Evidence IEA]; go_function: GO:0003774 - motor activity [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0051015 - actin filament binding [Evidence IEA] AKAW2_70759S BUSCO:EOG09264YHS; COG:F; EggNog:ENOG410PMXY; InterPro:IPR029001,IPR027502,IPR002637; PFAM:PF01725; go_function: GO:0047429 - nucleoside-triphosphate diphosphatase activity [Evidence IEA]; go_process: GO:0009143 - nucleoside triphosphate catabolic process [Evidence IEA] AKAW2_70760A BUSCO:EOG09264XPY; COG:F; EggNog:ENOG410PKWX; InterPro:IPR027417,IPR020618; PFAM:PF13207,PF13238; go_function: GO:0004017 - adenylate kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA] AKAW2_70761A COG:S; EggNog:ENOG410PFM1; InterPro:IPR012462; MEROPS:MER1108685; PFAM:PF07910 AKAW2_70762S COG:E; EggNog:ENOG410PFFF; InterPro:IPR027795,IPR001048,IPR001341,IPR036393, IPR018042,IPR002912,IPR041747; PFAM:PF01842,PF13840,PF00696; go_function: GO:0004072 - aspartate kinase activity [Evidence IEA]; go_process: GO:0008652 - cellular amino acid biosynthetic process [Evidence IEA] AKAW2_70763S COG:K; EggNog:ENOG410PHR6; InterPro:IPR030456,IPR001766,IPR036390,IPR036388; PFAM:PF00250; go_function: GO:0003700 - DNA-binding transcription factor activity [Evidence IEA]; go_function: GO:0043565 - sequence-specific DNA binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_70764A BUSCO:EOG092652KR; COG:K; EggNog:ENOG410PPA2; InterPro:IPR018230,IPR001748; PFAM:PF01125; go_component: GO:0005634 - nucleus [Evidence IEA] AKAW2_70765S COG:U; EggNog:ENOG410PQY8; InterPro:IPR004217,IPR035427,IPR039238; PFAM:PF02953; go_component: GO:0005758 - mitochondrial intermembrane space [Evidence IEA]; go_process: GO:0072321 - chaperone-mediated protein transport [Evidence IEA] AKAW2_70766A BUSCO:EOG092657YR; COG:J; EggNog:ENOG410PPAS; InterPro:IPR005633,IPR012678,IPR013025,IPR012677; PFAM:PF00276,PF03939; go_component: GO:0005840 - ribosome [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_process: GO:0006412 - translation [Evidence IEA] AKAW2_70767S BUSCO:EOG09263PWF; COG:S; EggNog:ENOG410PI7W; InterPro:IPR021867,IPR029063; PFAM:PF11968 AKAW2_70768A COG:E; EggNog:ENOG410PFIN; InterPro:IPR013057; PFAM:PF01490; TransMembrane:10 (o252-272i302-324o330-350i357-382o402-427i439-460o480- 497i540-557o563-586i598-620o) AKAW2_70769S BUSCO:EOG09262CDO; COG:J; EggNog:ENOG410PGF4; InterPro:IPR004403,IPR029064,IPR005142,IPR005140, IPR005141,IPR042226,IPR024049; PFAM:PF03463,PF03465,PF18854,PF03464; go_function: GO:0003747 - translation release factor activity [Evidence IEA]; go_process: GO:0006415 - translational termination [Evidence IEA] AKAW2_70770A COG:E; EggNog:ENOG410PJU6; InterPro:IPR001086,IPR002912,IPR008242; PFAM:PF00800; go_function: GO:0004106 - chorismate mutase activity [Evidence IEA]; go_function: GO:0004664 - prephenate dehydratase activity [Evidence IEA]; go_process: GO:0009094 - L-phenylalanine biosynthetic process [Evidence IEA] AKAW2_70771S COG:S; EggNog:ENOG410PP7B; InterPro:IPR029069 AKAW2_70772S COG:S; EggNog:ENOG410PPP7; InterPro:IPR007599; PFAM:PF04511; TransMembrane:4 (o14-37i49-73o93-126i138-163o) AKAW2_70773S BUSCO:EOG0926273Q; COG:J; EggNog:ENOG410PFV3; InterPro:IPR012960,IPR020103,IPR032819,IPR004802, IPR002501,IPR015947,IPR004521,IPR002478; PFAM:PF16198,PF08068,PF01509,PF01472; go_function: GO:0003723 - RNA binding [Evidence IEA]; go_function: GO:0009982 - pseudouridine synthase activity [Evidence IEA]; go_process: GO:0001522 - pseudouridine synthesis [Evidence IEA]; go_process: GO:0006396 - RNA processing [Evidence IEA]; go_process: GO:0009451 - RNA modification [Evidence IEA] AKAW2_70774S BUSCO:EOG09261O7R; COG:S; EggNog:ENOG410PGQ3; InterPro:IPR024964,IPR044063,IPR027714,IPR006594, IPR006595,IPR013144; PFAM:PF10607; go_function: GO:0004842 - ubiquitin-protein transferase activity [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0045721 - negative regulation of gluconeogenesis [Evidence IEA] AKAW2_70775A BUSCO:EOG09263W48; COG:S; EggNog:ENOG410PMQX; InterPro:IPR019446; PFAM:PF10354 AKAW2_70776A COG:G; EggNog:ENOG410PGF5; InterPro:IPR000620,IPR038736; PFAM:PF00892; TransMembrane:9 (o45-66i73-91o111-132i153-181o201-220i236-254o274-296i303- 323o329-348i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0005458 - GDP-mannose transmembrane transporter activity [Evidence IEA] AKAW2_70778S COG:C,O; EggNog:ENOG410PR62; InterPro:IPR036249 AKAW2_70777A COG:G; EggNog:ENOG410PJXD; InterPro:IPR018958,IPR009203; PFAM:PF09346; go_process: GO:0042546 - cell wall biogenesis [Evidence IEA] AKAW2_70779A COG:S; EggNog:ENOG410PX6I; PFAM:PF15365 AKAW2_70780S BUSCO:EOG09265AT5; COG:O; EggNog:ENOG410PNSJ; InterPro:IPR024766,IPR001841,IPR013083; PFAM:PF12861,PF12678; go_function: GO:0008270 - zinc ion binding [Evidence IEA] AKAW2_70781A COG:U; EggNog:ENOG410PQQ0; InterPro:IPR037713,IPR009542; PFAM:PF06645; TransMembrane:2 (i26-46o52-71i); go_component: GO:0005787 - signal peptidase complex [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_process: GO:0006465 - signal peptide processing [Evidence IEA] AKAW2_70782A COG:E; EggNog:ENOG410PISC; InterPro:IPR013750,IPR000870,IPR006203,IPR006204, IPR036554,IPR020568,IPR014721; PFAM:PF00288,PF08544; go_function: GO:0004413 - homoserine kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006566 - threonine metabolic process [Evidence IEA] AKAW2_70783S COG:P; EggNog:ENOG410PG66; InterPro:IPR044089,IPR002523; PFAM:PF01544; TransMembrane:2 (i601-624o636-657i); go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0015095 - magnesium ion transmembrane transporter activity [Evidence IEA]; go_function: GO:0046873 - metal ion transmembrane transporter activity [Evidence IEA]; go_process: GO:0030001 - metal ion transport [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA]; go_process: GO:1903830 - magnesium ion transmembrane transport [Evidence IEA] AKAW2_70784S BUSCO:EOG09261S7X; COG:S; EggNog:ENOG410PIPW; InterPro:IPR024338; PFAM:PF12929; TransMembrane:1 (n20-32c37/38o598-615i); go_function: GO:0005262 - calcium channel activity [Evidence IEA]; go_process: GO:0098703 - calcium ion import across plasma membrane [Evidence IEA] AKAW2_70785A COG:S; EggNog:ENOG410PJD2; InterPro:IPR019148; PFAM:PF09751 AKAW2_70786A COG:S; EggNog:ENOG410Q09V; InterPro:IPR000095 AKAW2_70787S TransMembrane:1 (o30-50i) AKAW2_70788A BUSCO:EOG09260EAZ; COG:P; EggNog:ENOG410PISN; InterPro:IPR011990,IPR019734,IPR013026,IPR031101; PFAM:PF13181; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA]; go_process: GO:0016570 - histone modification [Evidence IEA] AKAW2_70789A COG:I; EggNog:ENOG410PIC2; InterPro:IPR032098,IPR002123; PFAM:PF16076,PF01553; TransMembrane:5 (i43-67o87-105i133-151o171-192i398-415o); go_function: GO:0016746 - transferase activity, transferring acyl groups [Evidence IEA] AKAW2_70790S COG:G; EggNog:ENOG410PI65; InterPro:IPR016064,IPR017437,IPR002504; PFAM:PF01513; go_function: GO:0003951 - NAD+ kinase activity [Evidence IEA]; go_process: GO:0006741 - NADP biosynthetic process [Evidence IEA]; go_process: GO:0019674 - NAD metabolic process [Evidence IEA] AKAW2_70791S COG:T; EggNog:ENOG410PFNT; InterPro:IPR000095,IPR008271,IPR011993,IPR001849, IPR033923,IPR000719,IPR011009,IPR036936; PFAM:PF15413,PF07714,PF00069,PF00786; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0004674 - protein serine/threonine kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_70792A COG:S; EggNog:ENOG410PIX3; InterPro:IPR015943; TransMembrane:1 (o437-458i); go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_70793A COG:J; EggNog:ENOG410PH5K; InterPro:IPR015943; SECRETED:SignalP(1-28); go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_70794A COG:J; EggNog:ENOG410PH5K; InterPro:IPR036621,IPR006195,IPR004154,IPR027031, IPR033731,IPR002314,IPR002315; PFAM:PF03129; go_component: GO:0005737 - cytoplasm [Evidence IEA]; go_function: GO:0000166 - nucleotide binding [Evidence IEA]; go_function: GO:0004812 - aminoacyl-tRNA ligase activity [Evidence IEA]; go_function: GO:0004820 - glycine-tRNA ligase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006418 - tRNA aminoacylation for protein translation [Evidence IEA]; go_process: GO:0006426 - glycyl-tRNA aminoacylation [Evidence IEA] AKAW2_70795S COG:J; EggNog:ENOG410PI8V; InterPro:IPR007109; PFAM:PF04427 AKAW2_70796A COG:S; EggNog:ENOG410PKR0; InterPro:IPR029063; PFAM:PF13489,PF13847,PF13649 AKAW2_70797S COG:J; EggNog:ENOG410PSBJ; InterPro:IPR001328,IPR036416; PFAM:PF01195; go_function: GO:0004045 - aminoacyl-tRNA hydrolase activity [Evidence IEA] AKAW2_70798A COG:U; EggNog:ENOG410PGVR; InterPro:IPR003005,IPR004148,IPR027267,IPR037429; PFAM:PF03114; go_component: GO:0005737 - cytoplasm [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0007015 - actin filament organization [Evidence IEA] AKAW2_70800A COG:T; EggNog:ENOG410PG7W; InterPro:IPR017441,IPR008271,IPR000719,IPR011009; PFAM:PF07714,PF00069; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_70801S COG:S; EggNog:ENOG410PT6D AKAW2_70802A COG:U; EggNog:ENOG410PNSF; InterPro:IPR007233,IPR011012; PFAM:PF04099; go_component: GO:0030008 - TRAPP complex [Evidence IEA]; go_process: GO:0016192 - vesicle-mediated transport [Evidence IEA] AKAW2_70803S COG:T; EggNog:ENOG410PHIQ; InterPro:IPR000719,IPR011009,IPR008271; PFAM:PF07714,PF00069; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_70806S BUSCO:EOG09261B14; COG:K; EggNog:ENOG410PGM7; InterPro:IPR001214,IPR006560,IPR001202,IPR036020, IPR003616,IPR013257,IPR038190,IPR025788; PFAM:PF17907,PF08236,PF00856; go_component: GO:0005634 - nucleus [Evidence IEA]; go_component: GO:0005694 - chromosome [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_function: GO:0018024 - histone-lysine N-methyltransferase activity [Evidence IEA]; go_function: GO:0046975 - histone methyltransferase activity (H3-K36 specific) [Evidence IEA]; go_process: GO:0006354 - DNA-templated transcription, elongation [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA]; go_process: GO:0010452 - histone H3-K36 methylation [Evidence IEA]; go_process: GO:0034968 - histone lysine methylation [Evidence IEA] AKAW2_70807A BUSCO:EOG092644O2; COG:J; EggNog:ENOG410PFYZ; InterPro:IPR002769; PFAM:PF01912; go_function: GO:0043022 - ribosome binding [Evidence IEA]; go_process: GO:0042256 - mature ribosome assembly [Evidence IEA] AKAW2_70809A COG:S; EggNog:ENOG410Q0DJ AKAW2_70810A COG:S; EggNog:ENOG410QEA2; TransMembrane:4 (i12-36o48-69i85-107o127-150i) AKAW2_70811S COG:L; EggNog:ENOG410PIGA; InterPro:IPR004806,IPR009060,IPR015360,IPR006636, IPR015940,IPR036353; PFAM:PF09280,PF00627; go_function: GO:0003684 - damaged DNA binding [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0006289 - nucleotide-excision repair [Evidence IEA]; go_process: GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process [Evidence IEA] AKAW2_70812A CAZy:GT22; COG:G; EggNog:ENOG410PG7I; InterPro:IPR005599; PFAM:PF03901; SECRETED:SignalP(1-17); TransMembrane:4 (n7-18c23/24o89-111i169-189o209-228i348-367o); go_function: GO:0016757 - transferase activity, transferring glycosyl groups [Evidence IEA] AKAW2_70813S BUSCO:EOG09264ZWF; COG:O; EggNog:ENOG410PN0Q; InterPro:IPR001232,IPR011333,IPR036296,IPR016072, IPR016073,IPR016897; PFAM:PF03931,PF01466; go_process: GO:0006511 - ubiquitin-dependent protein catabolic process [Evidence IEA] AKAW2_70814A COG:J; EggNog:ENOG410PRU9; InterPro:IPR023626,IPR000077; PFAM:PF00832; go_component: GO:0005840 - ribosome [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_process: GO:0006412 - translation [Evidence IEA] AKAW2_70816S COG:Q; EggNog:ENOG410PGKJ; InterPro:IPR017871,IPR027417,IPR003593,IPR039421, IPR011527,IPR003439,IPR036640; PFAM:PF00005,PF00664; TransMembrane:12 (i112-145o165-186i238-256o262-285i343-364o376-396i783- 806o826-854i905-925o931-951i1013-1033o1045-1068i); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA]; go_function: GO:0042626 - ATPase-coupled transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_70817A COG:L; EggNog:ENOG410PTNP; InterPro:IPR010760; PFAM:PF07061 AKAW2_70818S COG:S; EggNog:ENOG410PJ4V; InterPro:IPR018827,IPR018825; PFAM:PF10355,PF10348; SECRETED:SignalP(1-26); TransMembrane:11 (n11-19c24/25o48-69i76-93o105-127i139-162o182-205i217- 234o246-265i277-294o300-321i342-361o381-403i) AKAW2_70819A COG:O; EggNog:ENOG410PGH4; InterPro:IPR000594,IPR035985,IPR000011; PFAM:PF00899; go_function: GO:0008641 - ubiquitin-like modifier activating enzyme activity [Evidence IEA]; go_process: GO:0006464 - cellular protein modification process [Evidence IEA] AKAW2_70820S COG:S; EggNog:ENOG410PMBB AKAW2_70821A COG:K; EggNog:ENOG410PGE4; InterPro:IPR039779,IPR036390,IPR036388,IPR003150; PFAM:PF02257; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0003700 - DNA-binding transcription factor activity [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_70822A COG:U; EggNog:ENOG410QDX6; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i58-79o91-114i126-142o154-172i184-209o215-234i284- 310o330-353i395-413o425-446i458-476o482-501i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_70823A BUSCO:EOG092638CT; COG:C; EggNog:ENOG410PFCD; InterPro:IPR017440,IPR016102,IPR005810,IPR005811, IPR036291,IPR033847,IPR003781; PFAM:PF02629,PF13607,PF00549; go_function: GO:0003824 - catalytic activity [Evidence IEA] AKAW2_70824S BUSCO:EOG09261VI3; COG:B,K; EggNog:ENOG410PG0I; InterPro:IPR006638,IPR023404,IPR016181,IPR007197, IPR039661,IPR032432,IPR000182,IPR034687; PFAM:PF04055,PF16199,PF00583; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0008080 - N-acetyltransferase activity [Evidence IEA]; go_function: GO:0051536 - iron-sulfur cluster binding [Evidence IEA] AKAW2_70825A COG:S; EggNog:ENOG410PSDZ; InterPro:IPR026770; TransMembrane:2 (i7-31o51-71i); go_function: GO:0004521 - endoribonuclease activity [Evidence IEA]; go_process: GO:0090305 - nucleic acid phosphodiester bond hydrolysis [Evidence IEA] AKAW2_70826A BUSCO:EOG092640IZ; COG:E; EggNog:ENOG410PGN7; InterPro:IPR011060,IPR006062,IPR011858,IPR013785; PFAM:PF00977; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0003949 - 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino) methylideneamino]imidazole-4-carboxamide isomerase activity [Evidence IEA]; go_process: GO:0000105 - histidine biosynthetic process [Evidence IEA] AKAW2_70827S COG:S; EggNog:ENOG410PSA1; InterPro:IPR027973; PFAM:PF15375 AKAW2_70828S COG:K; EggNog:ENOG410PFQA; InterPro:IPR036236,IPR003120,IPR013087; PFAM:PF13894,PF02200,PF00096; go_component: GO:0005634 - nucleus [Evidence IEA]; go_function: GO:0003700 - DNA-binding transcription factor activity [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_70829S COG:G; EggNog:ENOG410PHUS; InterPro:IPR036259; TransMembrane:10 (i52-68o88-111i123-142o162-181i207-227o239-261i305- 327o352-376i447-468o474-495i) AKAW2_70830S COG:P; EggNog:ENOG410PHYC; InterPro:IPR004709,IPR006153,IPR018422; PFAM:PF00999; TransMembrane:13 (o38-60i72-89o101-120i132-154o166-190i197-216o236-262i274- 290o296-315i327-346o358-383i404-427o433-455i); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0015299 - solute:proton antiporter activity [Evidence IEA]; go_function: GO:0015385 - sodium:proton antiporter activity [Evidence IEA]; go_process: GO:0006812 - cation transport [Evidence IEA]; go_process: GO:0006814 - sodium ion transport [Evidence IEA]; go_process: GO:0006885 - regulation of pH [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_70831S COG:E; EggNog:ENOG410PFV8; InterPro:IPR002293; PFAM:PF13520; TransMembrane:10 (i33-56o68-90i97-116o144-164i176-203o232-253i284-304o310- 333i353-370o382-403i); go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_70832A COG:Q; EggNog:ENOG410PH61; InterPro:IPR013154,IPR013149,IPR002328,IPR036291, IPR011032,IPR020843; PFAM:PF00107,PF08240; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_70833S COG:L; EggNog:ENOG410PFTZ; InterPro:IPR027417,IPR000330,IPR038718,IPR001650, IPR020838,IPR014001,IPR031047; PFAM:PF00176,PF00271,PF04851,PF13892; go_component: GO:0005634 - nucleus [Evidence IEA]; go_component: GO:0031011 - Ino80 complex [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA]; go_process: GO:0006281 - DNA repair [Evidence IEA]; go_process: GO:0006338 - chromatin remodeling [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA] AKAW2_70834S BUSCO:EOG09261NLR; COG:H; EggNog:ENOG410PHKA; InterPro:IPR001917,IPR004839,IPR015424,IPR010961, IPR015421,IPR015422; PFAM:PF00155; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0003870 - 5-aminolevulinate synthase activity [Evidence IEA]; go_function: GO:0016740 - transferase activity [Evidence IEA]; go_function: GO:0030170 - pyridoxal phosphate binding [Evidence IEA]; go_process: GO:0009058 - biosynthetic process [Evidence IEA]; go_process: GO:0033014 - tetrapyrrole biosynthetic process [Evidence IEA] AKAW2_70835A BUSCO:EOG09262BVA; COG:K; EggNog:ENOG410PITZ; InterPro:IPR009668; PFAM:PF06870; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA] AKAW2_70836A COG:G; EggNog:ENOG410Q6M2; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:11 (n11-21c29/30o48-68i75-94o106-123i135-156o168-190i239- 259o279-296i303-321o333-356i368-387o399-421i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_70837A COG:U; EggNog:ENOG410PI1H; InterPro:IPR006966; PFAM:PF04882; TransMembrane:1 (i16-34o); go_component: GO:0005779 - integral component of peroxisomal membrane [Evidence IEA]; go_process: GO:0007031 - peroxisome organization [Evidence IEA] AKAW2_70838S COG:S; EggNog:ENOG410PJG8; InterPro:IPR012445; PFAM:PF07855; go_process: GO:0006914 - autophagy [Evidence IEA] AKAW2_70839A BUSCO:EOG09264USX; COG:U; EggNog:ENOG410PP88; InterPro:IPR004345; PFAM:PF03134; TransMembrane:2 (i37-68o88-111i) AKAW2_70840A COG:K; EggNog:ENOG410PH8Z; InterPro:IPR027417,IPR036427,IPR014978,IPR000330, IPR038718,IPR001650,IPR014001,IPR029295,IPR001487, IPR014012; PFAM:PF00176,PF00439,PF08880,PF14619,PF07529, PF00271,PF04851; go_component: GO:0005634 - nucleus [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0042393 - histone binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_70841A COG:I,T; EggNog:ENOG410PI7Q; InterPro:IPR004148,IPR027267; PFAM:PF03114; go_component: GO:0005737 - cytoplasm [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_70842S COG:T; EggNog:ENOG410PUBJ; InterPro:IPR000719,IPR011009,IPR001245; PFAM:PF00069; TransMembrane:1 (o277-297i); go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_70843A COG:L; EggNog:ENOG410PRFJ; InterPro:IPR009057,IPR004026,IPR035451,IPR018060; PFAM:PF00165,PF02805; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0003700 - DNA-binding transcription factor activity [Evidence IEA]; go_function: GO:0008168 - methyltransferase activity [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_function: GO:0043565 - sequence-specific DNA binding [Evidence IEA]; go_process: GO:0006281 - DNA repair [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_70844A COG:J; EggNog:ENOG410PIUY; InterPro:IPR022669,IPR008991,IPR022671,IPR022666, IPR014726,IPR002171,IPR012340,IPR014722; PFAM:PF03947,PF00181; go_component: GO:0005840 - ribosome [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_process: GO:0006412 - translation [Evidence IEA] AKAW2_70845S COG:S; EggNog:ENOG410PKIA; InterPro:IPR028942; PFAM:PF15612 AKAW2_70846A COG:S; EggNog:ENOG410PPTY; InterPro:IPR013898; PFAM:PF08589 AKAW2_70847S COG:F; EggNog:ENOG410PHCU; InterPro:IPR029056,IPR001805,IPR011611; PFAM:PF00294; go_function: GO:0004001 - adenosine kinase activity [Evidence IEA]; go_process: GO:0006166 - purine ribonucleoside salvage [Evidence IEA] AKAW2_70848A COG:A; EggNog:ENOG410QDF2; InterPro:IPR018834,IPR019458,IPR011990; PFAM:PF10374,PF10373; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_70849S COG:U; EggNog:ENOG410PQTV; InterPro:IPR039258,IPR013087 AKAW2_70850A COG:K; EggNog:ENOG410PFYS; InterPro:IPR036236,IPR007219,IPR013087; PFAM:PF13894,PF04082,PF00096; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA] AKAW2_70851S COG:T; EggNog:ENOG410PG4H; InterPro:IPR017441,IPR008271,IPR000159,IPR001660, IPR000719,IPR029458,IPR011009,IPR013761; PFAM:PF07647,PF00069,PF07714,PF00536,PF14847, PF00788; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA]; go_process: GO:0007165 - signal transduction [Evidence IEA] AKAW2_70852A BUSCO:EOG09264K2W; COG:J; EggNog:ENOG410PIM5; InterPro:IPR002132,IPR031309,IPR022803; PFAM:PF00673; go_component: GO:0005840 - ribosome [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_process: GO:0006412 - translation [Evidence IEA] AKAW2_70853S COG:O; EggNog:ENOG410PGUJ; InterPro:IPR028889,IPR038765,IPR001394; MEROPS:MER0004663; PFAM:PF00443,PF13423; go_function: GO:0004843 - thiol-dependent ubiquitin-specific protease activity [Evidence IEA]; go_process: GO:0016579 - protein deubiquitination [Evidence IEA] AKAW2_70854S BUSCO:EOG09260HS3; COG:U; EggNog:ENOG410PHIT; InterPro:IPR007810,IPR011990,IPR000547; PFAM:PF05131; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0006886 - intracellular protein transport [Evidence IEA]; go_process: GO:0016192 - vesicle-mediated transport [Evidence IEA] AKAW2_70856S COG:T; EggNog:ENOG410PHIU; InterPro:IPR000719,IPR011009,IPR008271; PFAM:PF07714,PF00069; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_70857S COG:I; EggNog:ENOG410PJQE; InterPro:IPR012919,IPR008979; PFAM:PF07738; SECRETED:SignalP(1-26); TransMembrane:1 (o678-699i) AKAW2_70858S COG:S; EggNog:ENOG410PSVG; InterPro:IPR007727; PFAM:PF05032 AKAW2_70859S COG:I; EggNog:ENOG410PH69; InterPro:IPR006091,IPR009075,IPR037069,IPR009100, IPR036250,IPR013786; PFAM:PF02770,PF00441,PF02771,PF08028; go_function: GO:0016627 - oxidoreductase activity, acting on the CH-CH group of donors [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_70860A BUSCO:EOG09262I5I; COG:S; EggNog:ENOG410PFXG; InterPro:IPR030378,IPR027417,IPR006073,IPR043358; go_function: GO:0003924 - GTPase activity [Evidence IEA]; go_function: GO:0005525 - GTP binding [Evidence IEA] AKAW2_70861S BUSCO:EOG09262VVF; COG:S; EggNog:ENOG410PJ3J; InterPro:IPR007307; PFAM:PF04180; go_process: GO:0042274 - ribosomal small subunit biogenesis [Evidence IEA] AKAW2_70862A BUSCO:EOG09261ICI; COG:I; EggNog:ENOG410PHGG; InterPro:IPR001736,IPR016270,IPR025202; PFAM:PF13091; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0008444 - CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity [Evidence IEA]; go_process: GO:0032049 - cardiolipin biosynthetic process [Evidence IEA] AKAW2_70863S COG:C; EggNog:ENOG410Q1EA; InterPro:IPR007763; PFAM:PF05071; go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0008137 - NADH dehydrogenase (ubiquinone) activity [Evidence IEA]; go_function: GO:0009055 - electron transfer activity [Evidence IEA] AKAW2_70864A COG:S; EggNog:ENOG410PJEU; InterPro:IPR011990,IPR019734; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_70865S COG:S; EggNog:ENOG410PMHN; InterPro:IPR016024,IPR012583; PFAM:PF08167 AKAW2_70866A COG:S; EggNog:ENOG410Q0Q4; InterPro:IPR032805; PFAM:PF13813; TransMembrane:7 (o33-52i59-76o88-107i231-249o357-375i387-406o418-440i) AKAW2_70868S COG:G; EggNog:ENOG410PFTW; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i70-87o107-125i137-155o167-188i195-220o226-246i303- 329o341-360i381-401o407-428i440-463o475-495i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_70869S COG:L; EggNog:ENOG410QDFR; InterPro:IPR014905,IPR001841,IPR027417,IPR003613, IPR000330,IPR038718,IPR001650,IPR014001,IPR013083; PFAM:PF13923,PF13639,PF00176,PF00097,PF13445, PF00271,PF13920,PF08797,PF11789; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0004842 - ubiquitin-protein transferase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_function: GO:0016818 - hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [Evidence IEA]; go_process: GO:0016567 - protein ubiquitination [Evidence IEA] AKAW2_70870A COG:K; EggNog:ENOG410PJEH; InterPro:IPR027417,IPR000330,IPR038718,IPR001650, IPR014001,IPR001660,IPR013761; PFAM:PF00176,PF07647,PF00271,PF04851; go_function: GO:0005515 - protein binding [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA] AKAW2_70871A COG:S; EggNog:ENOG410PXAP AKAW2_70872S COG:S; EggNog:ENOG410PU43; InterPro:IPR003746,IPR036591; PFAM:PF02594 AKAW2_70873S COG:A; EggNog:ENOG410PRZZ; InterPro:IPR020347; go_component: GO:0000172 - ribonuclease MRP complex [Evidence IEA]; go_component: GO:0005655 - nucleolar ribonuclease P complex [Evidence IEA]; go_process: GO:0006379 - mRNA cleavage [Evidence IEA]; go_process: GO:0008033 - tRNA processing [Evidence IEA] AKAW2_70874A COG:S; EggNog:ENOG410PHYB; InterPro:IPR021134; PFAM:PF01062; TransMembrane:4 (i93-111o117-137i327-348o354-373i) AKAW2_70875A COG:C; EggNog:ENOG410PH14; InterPro:IPR015590,IPR044086,IPR029510,IPR016160, IPR016161,IPR016162,IPR016163; PFAM:PF00171; antiSMASH:Cluster_7.5; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0016620 - oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_70876S COG:S; EggNog:ENOG410PNMU; TransMembrane:7 (o26-48i60-80o106-127i139-166o186-214i226-249o261-285i); antiSMASH:Cluster_7.5 AKAW2_70877A antiSMASH:Cluster_7.5 AKAW2_70878A COG:G; EggNog:ENOG410PFAF; InterPro:IPR005000,IPR015813,IPR040442; PFAM:PF03328; antiSMASH:Cluster_7.5; go_function: GO:0003824 - catalytic activity [Evidence IEA] AKAW2_70879S antiSMASH:Cluster_7.5 AKAW2_70880A COG:S; EggNog:ENOG410Q2UF; InterPro:IPR014710,IPR011051; SECRETED:SignalP(1-19); antiSMASH:Cluster_7.5 AKAW2_70881S COG:G; EggNog:ENOG410PHC6; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; SMCOG1005:Drug resistance transporter, EmrB/QacA; TransMembrane:12 (i58-79o91-114i126-146o152-174i186-209o221-243i288- 314o326-346i366-388o394-415i427-450o462-484i); antiSMASH:Cluster_7.5; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_70882S COG:S; EggNog:ENOG410PSYS; InterPro:IPR037401,IPR032710; PFAM:PF13577; antiSMASH:Cluster_7.5 AKAW2_70883A COG:C; EggNog:ENOG410PJ84; InterPro:IPR006094,IPR036318,IPR016166,IPR016167, IPR016169; PFAM:PF01565; SMCOG1138:FAD linked oxidase domain protein; antiSMASH:Cluster_7.5; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_function: GO:0071949 - FAD binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_70884A COG:I; EggNog:ENOG410PJBH; InterPro:IPR016036,IPR032088,IPR016035,IPR029063, IPR016039,IPR018201,IPR014030,IPR014031,IPR001227, IPR041068,IPR006162,IPR014043,IPR020841,IPR009081, IPR036736,IPR036291,IPR013217,IPR013120; PFAM:PF07993,PF00550,PF16073,PF13489,PF13649, PF02801,PF00698,PF01370,PF00109,PF08242,PF08241,PF13847, PF18558; SMCOG1093:Beta-ketoacyl synthase; antiSMASH:Cluster_7.5; go_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein] synthase activity [Evidence IEA]; go_function: GO:0016740 - transferase activity [Evidence IEA]; go_function: GO:0016746 - transferase activity, transferring acyl groups [Evidence IEA]; go_process: GO:0006633 - fatty acid biosynthetic process [Evidence IEA] AKAW2_70885A COG:S; EggNog:ENOG410PIW7; InterPro:IPR005645,IPR029058; PFAM:PF03959; antiSMASH:Cluster_7.5 AKAW2_70886S COG:Q; EggNog:ENOG410PIRX; InterPro:IPR026992,IPR027443,IPR005123; PFAM:PF03171,PF14226; antiSMASH:Cluster_7.5; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_70887S COG:Q; EggNog:ENOG410PMN1; InterPro:IPR002935,IPR029063; PFAM:PF03602,PF08241,PF01596,PF13578,PF13847; antiSMASH:Cluster_7.5; go_function: GO:0008171 - O-methyltransferase activity [Evidence IEA] AKAW2_70888S COG:C; EggNog:ENOG410QE5G; InterPro:IPR036291,IPR029752,IPR006140; SMCOG1072:dehydrogenase; antiSMASH:Cluster_7.5; go_function: GO:0051287 - NAD binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_70889A COG:S; EggNog:ENOG410PWP8; InterPro:IPR036864,IPR001138; PFAM:PF00172; TransMembrane:1 (o394-411i); antiSMASH:Cluster_7.5; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_70890S COG:E; EggNog:ENOG410PHBB; InterPro:IPR004631,IPR005814,IPR015424,IPR015421, IPR015422; PFAM:PF00202; SMCOG1013:aminotransferase class-III; antiSMASH:Cluster_7.5; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0003867 - 4-aminobutyrate transaminase activity [Evidence IEA]; go_function: GO:0008483 - transaminase activity [Evidence IEA]; go_function: GO:0030170 - pyridoxal phosphate binding [Evidence IEA]; go_process: GO:0009448 - gamma-aminobutyric acid metabolic process [Evidence IEA] AKAW2_70891A BUSCO:EOG09265BBJ; COG:K; EggNog:ENOG410PQ6M; InterPro:IPR009287,IPR022800,IPR038510,IPR029040; PFAM:PF06093; antiSMASH:Cluster_7.5; go_component: GO:0005634 - nucleus [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA]; go_process: GO:0032786 - positive regulation of DNA-templated transcription, elongation [Evidence IEA] AKAW2_70892S BUSCO:EOG09261M78; COG:T; EggNog:ENOG410PGEW; InterPro:IPR029052,IPR019734,IPR006186,IPR013026, IPR004843,IPR041753,IPR011990,IPR013235,IPR011236; PFAM:PF08321,PF00149; antiSMASH:Cluster_7.5; go_function: GO:0004721 - phosphoprotein phosphatase activity [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_function: GO:0016787 - hydrolase activity [Evidence IEA]; go_process: GO:0006470 - protein dephosphorylation [Evidence IEA] AKAW2_70893S COG:T; EggNog:ENOG410PGEW; InterPro:IPR036075,IPR002791,IPR039763; PFAM:PF01937; antiSMASH:Cluster_7.5; go_function: GO:0051998 - protein carboxyl O-methyltransferase activity [Evidence IEA] AKAW2_70894A COG:S; EggNog:ENOG410PPK6; InterPro:IPR021589; PFAM:PF11500; antiSMASH:Cluster_7.5 AKAW2_70895S COG:J; EggNog:ENOG410PHNI; InterPro:IPR036621,IPR017441,IPR008271,IPR016135, IPR006575,IPR041715,IPR024435,IPR016255,IPR000719, IPR011009; PFAM:PF07714,PF13393,PF12745,PF05773,PF00069; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0004694 - eukaryotic translation initiation factor 2alpha kinase activity [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0000077 - DNA damage checkpoint [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA]; go_process: GO:0010998 - regulation of translational initiation by eIF2 alpha phosphorylation [Evidence IEA] AKAW2_70896A COG:A; EggNog:ENOG410PG3V; InterPro:IPR000504,IPR032297,IPR034181,IPR012677, IPR039171,IPR039173,IPR035979,IPR000571,IPR036855; PFAM:PF00642,PF16131,PF00076; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0003723 - RNA binding [Evidence IEA]; go_function: GO:0017070 - U6 snRNA binding [Evidence IEA]; go_function: GO:0036002 - pre-mRNA binding [Evidence IEA]; go_function: GO:0046872 - metal ion binding [Evidence IEA]; go_process: GO:0000387 - spliceosomal snRNP assembly [Evidence IEA]; go_process: GO:0045292 - mRNA cis splicing, via spliceosome [Evidence IEA] AKAW2_70897S COG:T; EggNog:ENOG410PG8U; InterPro:IPR027417,IPR005225,IPR012675,IPR031662, IPR006074,IPR006073,IPR031167,IPR012676,IPR004095; PFAM:PF02421,PF02824,PF01926,PF16897; go_function: GO:0005525 - GTP binding [Evidence IEA] AKAW2_70898S COG:O; EggNog:ENOG410PU84; InterPro:IPR011118,IPR029058; PFAM:PF07519; SECRETED:SignalP(1-19) AKAW2_70899A COG:T; EggNog:ENOG410PW4Q; InterPro:IPR000719,IPR011009,IPR017441; PFAM:PF00069; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_70900A BUSCO:EOG09262914; COG:F; EggNog:ENOG410QEEE; InterPro:IPR035686,IPR036480,IPR017926,IPR029062, IPR002474,IPR006274; MEROPS:MER0060647; PFAM:PF00988,PF00117; go_function: GO:0004088 - carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [Evidence IEA]; go_process: GO:0006207 - 'de novo' pyrimidine nucleobase biosynthetic process [Evidence IEA]; go_process: GO:0006541 - glutamine metabolic process [Evidence IEA] AKAW2_70901S COG:S; EggNog:ENOG410Q28Z; InterPro:IPR032710; SECRETED:SignalP(1-18) AKAW2_70902A COG:Q; EggNog:ENOG410PFT4; InterPro:IPR036291,IPR002347; PFAM:PF00106,PF13561; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_70903A COG:S; EggNog:ENOG410PN18; InterPro:IPR001138,IPR036864; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_70904S COG:K; EggNog:ENOG410PVFB; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; TransMembrane:1 (i192-212o); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_70905A COG:O; EggNog:ENOG410PHSH; InterPro:IPR042322,IPR013233; PFAM:PF08320; TransMembrane:1 (o476-494i); go_component: GO:0005789 - endoplasmic reticulum membrane [Evidence IEA]; go_function: GO:0000030 - mannosyltransferase activity [Evidence IEA]; go_process: GO:0006506 - GPI anchor biosynthetic process [Evidence IEA] AKAW2_70906A BUSCO:EOG092641A6; COG:O; EggNog:ENOG410PKB4; InterPro:IPR008971,IPR002939,IPR001623,IPR036869, IPR018253; PFAM:PF00226,PF01556; go_function: GO:0051082 - unfolded protein binding [Evidence IEA]; go_process: GO:0006457 - protein folding [Evidence IEA] AKAW2_70907A COG:O; EggNog:ENOG410PIFS; InterPro:IPR001563,IPR033124,IPR029058; MEROPS:MER0016549; PFAM:PF00450; SECRETED:SignalP(1-20); go_function: GO:0004185 - serine-type carboxypeptidase activity [Evidence IEA]; go_process: GO:0006508 - proteolysis [Evidence IEA] AKAW2_70908A COG:S; EggNog:ENOG410PHQA; InterPro:IPR007461; PFAM:PF04366 AKAW2_70909A BUSCO:EOG09263WWI; COG:C; EggNog:ENOG410PFI6; InterPro:IPR033948,IPR014730,IPR012255,IPR014729; PFAM:PF01012; go_function: GO:0009055 - electron transfer activity [Evidence IEA] AKAW2_70910A BUSCO:EOG09261QR5; COG:C; EggNog:ENOG410PFF9; InterPro:IPR003097,IPR001433,IPR001094,IPR017927, IPR001709,IPR023173,IPR029039,IPR028879,IPR008254, IPR017938,IPR039261; PFAM:PF00175,PF00258,PF00667; go_function: GO:0003958 - NADPH-hemoprotein reductase activity [Evidence IEA]; go_function: GO:0010181 - FMN binding [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_70911A COG:F; EggNog:ENOG410PS6D; InterPro:IPR024661; PFAM:PF11705; go_process: GO:0006383 - transcription by RNA polymerase III [Evidence IEA] AKAW2_70912A COG:S; EggNog:ENOG410PJ1M AKAW2_70913S COG:O,T; EggNog:ENOG410PH1R; InterPro:IPR024969,IPR033859,IPR037518,IPR000555; PFAM:PF13012; go_component: GO:0008180 - COP9 signalosome [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_function: GO:0008237 - metallopeptidase activity [Evidence IEA]; go_function: GO:0070122 - isopeptidase activity [Evidence IEA]; go_process: GO:0000338 - protein deneddylation [Evidence IEA] AKAW2_70914A COG:T; EggNog:ENOG410PM3Y; InterPro:IPR005178; PFAM:PF03619; TransMembrane:7 (o27-49i69-88o100-118i160-185o205-227i239-262o282-303i) AKAW2_70915A COG:S; EggNog:ENOG410PP6Z; InterPro:IPR034257,IPR003034,IPR032552,IPR036361; PFAM:PF02037 AKAW2_70916S COG:E; EggNog:ENOG410PJ6Z; InterPro:IPR006076,IPR036188; PFAM:PF01266; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_70917A COG:S; EggNog:ENOG410PX2U; InterPro:IPR001138,IPR036864; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_70918S COG:Q; EggNog:ENOG410PVRX; InterPro:IPR013149,IPR011032,IPR020843,IPR036291; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_70919S COG:E; EggNog:ENOG410PF9D; InterPro:IPR000073,IPR008220,IPR029058; MEROPS:MER0044357; go_function: GO:0016747 - transferase activity, transferring acyl groups other than amino-acyl groups [Evidence IEA]; go_process: GO:0009058 - biosynthetic process [Evidence IEA] AKAW2_70920S COG:E; EggNog:ENOG410PF9D; InterPro:IPR000073,IPR008220,IPR029058; MEROPS:MER0044357; PFAM:PF00561; go_function: GO:0016747 - transferase activity, transferring acyl groups other than amino-acyl groups [Evidence IEA]; go_process: GO:0009058 - biosynthetic process [Evidence IEA] AKAW2_70921S COG:S; EggNog:ENOG410Q2UR AKAW2_70922A TransMembrane:1 (o22-46i) AKAW2_70924A COG:S; EggNog:ENOG410Q1Z5 AKAW2_70926A COG:S; EggNog:ENOG410PXKE AKAW2_70927A COG:S; EggNog:ENOG410PXKE; TransMembrane:7 (o20-40i52-77o97-119i126-148o180-201i213-233o245-274i) AKAW2_70928S COG:S; EggNog:ENOG410PNH6; InterPro:IPR036291 AKAW2_70929A COG:J; EggNog:ENOG410PGST; InterPro:IPR000640,IPR027417,IPR035647,IPR005225, IPR041095,IPR035649,IPR000795,IPR031157,IPR009022, IPR030851,IPR020568,IPR009000; PFAM:PF14492,PF00009,PF00679; go_component: GO:0005739 - mitochondrion [Evidence IEA]; go_function: GO:0003924 - GTPase activity [Evidence IEA]; go_function: GO:0005525 - GTP binding [Evidence IEA]; go_process: GO:0032790 - ribosome disassembly [Evidence IEA] AKAW2_70930S BUSCO:EOG09261IEH; COG:U; EggNog:ENOG410PGQ6; InterPro:IPR027267,IPR014461,IPR037907,IPR001683, IPR036871,IPR015404; PFAM:PF09325,PF00787; go_component: GO:0030904 - retromer complex [Evidence IEA]; go_function: GO:0035091 - phosphatidylinositol binding [Evidence IEA]; go_process: GO:0015031 - protein transport [Evidence IEA]; go_process: GO:0042147 - retrograde transport, endosome to Golgi [Evidence IEA] AKAW2_70931S COG:S; EggNog:ENOG410PHFD; InterPro:IPR036291,IPR016040 AKAW2_70932S BUSCO:EOG092605VL; COG:K; EggNog:ENOG410PF9C; InterPro:IPR021726,IPR032302,IPR040007,IPR021418; PFAM:PF11732,PF11262,PF16134; TransMembrane:2 (o541-560i656-676o); go_component: GO:0000347 - THO complex [Evidence IEA]; go_process: GO:0006397 - mRNA processing [Evidence IEA]; go_process: GO:0006406 - mRNA export from nucleus [Evidence IEA] AKAW2_70933S CAZy:GH3; COG:G; EggNog:ENOG410PFI5; InterPro:IPR017853,IPR019800,IPR036962,IPR037524, IPR008979,IPR002772,IPR036881,IPR026891,IPR013783, IPR001764,IPR011658; PFAM:PF00933,PF01915,PF14310,PF07691; go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_70937A COG:T; EggNog:ENOG410PG8M; InterPro:IPR001164,IPR037278,IPR038508; PFAM:PF01412; go_function: GO:0005096 - GTPase activator activity [Evidence IEA] AKAW2_70938S COG:O,P; EggNog:ENOG410PM1Q; InterPro:IPR007484; MEROPS:MER0032443; PFAM:PF04389; SECRETED:SignalP(1-17) AKAW2_70939A COG:S; EggNog:ENOG410QDT7; InterPro:IPR000504,IPR012677,IPR035979; PFAM:PF00076; go_function: GO:0003676 - nucleic acid binding [Evidence IEA] AKAW2_70941S COG:C; EggNog:ENOG410PKDH; InterPro:IPR023210,IPR036812; PFAM:PF00248 AKAW2_70942S COG:S; EggNog:ENOG410PI25; InterPro:IPR021369; PFAM:PF11204; TransMembrane:4 (i343-371o377-398i499-525o531-554i) AKAW2_70943A COG:S; EggNog:ENOG410PVS1; InterPro:IPR007568; PFAM:PF04479; TransMembrane:7 (o20-40i47-66o78-102i114-135o155-178i190-212o232-250i); go_component: GO:0016021 - integral component of membrane [Evidence IEA] AKAW2_70944S COG:S; EggNog:ENOG410PWZR; InterPro:IPR036864,IPR001138; PFAM:PF00172; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_70946A COG:S; EggNog:ENOG410QDV2; InterPro:IPR031968,IPR011993,IPR040147,IPR004182; PFAM:PF02893,PF16016; TransMembrane:1 (o1104-1123i) AKAW2_70947S COG:S; EggNog:ENOG410PKE0 AKAW2_70948A CAZy:GH3; COG:G; EggNog:ENOG410PMFK; InterPro:IPR017853,IPR036962,IPR002772,IPR036881, IPR026891,IPR013783,IPR001764; PFAM:PF14310,PF00933,PF01915; SECRETED:SignalP(1-21); go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_70949A COG:S; EggNog:ENOG410PJBB; InterPro:IPR008521; PFAM:PF05653; SECRETED:SignalP(1-21); TransMembrane:8 (n7-18c23/24o63-85i208-229o235-255i264-282o302-321i328- 344o356-375i396-416o); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0015095 - magnesium ion transmembrane transporter activity [Evidence IEA]; go_process: GO:0015693 - magnesium ion transport [Evidence IEA] AKAW2_70950A COG:O; EggNog:ENOG410PK80; InterPro:IPR036322,IPR015943,IPR019775,IPR001680, IPR017986; PFAM:PF00400; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_70951A COG:O; EggNog:ENOG410PICC; InterPro:IPR041569,IPR003960,IPR003959,IPR027417, IPR003593,IPR032501,IPR005937; PFAM:PF16450,PF00004,PF17862,PF07728,PF07724; go_component: GO:0005737 - cytoplasm [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016787 - hydrolase activity [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA]; go_process: GO:0030163 - protein catabolic process [Evidence IEA] AKAW2_70952S COG:O; EggNog:ENOG410PI5J; InterPro:IPR000608,IPR009060,IPR016135,IPR023313, IPR015368; PFAM:PF09288,PF00179; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_70953S BUSCO:EOG09263SFX; COG:D; EggNog:ENOG410PMZ9; InterPro:IPR036915,IPR031658,IPR043198,IPR006671, IPR013763; PFAM:PF00134,PF16899; go_function: GO:0016538 - cyclin-dependent protein serine/threonine kinase regulator activity [Evidence IEA]; go_process: GO:0006357 - regulation of transcription by RNA polymerase II [Evidence IEA] AKAW2_70954A BUSCO:EOG092614E6; COG:J; EggNog:ENOG410PH57; InterPro:IPR017871,IPR027417,IPR003593,IPR003439, IPR032781; PFAM:PF12848,PF00005; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA] AKAW2_70955A COG:T; EggNog:ENOG410PMXU; InterPro:IPR007065; PFAM:PF04982; TransMembrane:4 (i59-80o92-111i123-141o189-211i) AKAW2_70956A COG:S; EggNog:ENOG410PJJ0; InterPro:IPR004104,IPR000683,IPR036291; PFAM:PF02894,PF01408; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA] AKAW2_70957A COG:Q; EggNog:ENOG410PW43; InterPro:IPR002935,IPR029063; PFAM:PF13578,PF01596; go_function: GO:0008171 - O-methyltransferase activity [Evidence IEA] AKAW2_70958S COG:S; EggNog:ENOG410PKIT AKAW2_70959S COG:S; EggNog:ENOG410PFNR; TransMembrane:4 (i16-36o48-66i78-104o158-181i) AKAW2_70960S COG:S; EggNog:ENOG410PFNR; InterPro:IPR011990; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_70961A COG:Q; EggNog:ENOG410PF88; InterPro:IPR015798,IPR016182,IPR036460,IPR000269, IPR015802,IPR015800; PFAM:PF01179,PF02728,PF02727; go_function: GO:0005507 - copper ion binding [Evidence IEA]; go_function: GO:0008131 - primary amine oxidase activity [Evidence IEA]; go_function: GO:0048038 - quinone binding [Evidence IEA]; go_process: GO:0009308 - amine metabolic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_70962A BUSCO:EOG09262K67; COG:A; EggNog:ENOG410PHN6; InterPro:IPR036397,IPR039637,IPR012337,IPR006941; go_component: GO:0030014 - CCR4-NOT complex [Evidence IEA]; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0004535 - poly(A)-specific ribonuclease activity [Evidence IEA] AKAW2_70963S COG:C; EggNog:ENOG410PS9B; InterPro:IPR012576; PFAM:PF08122; go_component: GO:0005739 - mitochondrion [Evidence IEA]; go_process: GO:0022900 - electron transport chain [Evidence IEA] AKAW2_70964A COG:I; EggNog:ENOG410PJYK; InterPro:IPR015943,IPR001680,IPR036322,IPR017986; PFAM:PF00400; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_70965A COG:I; EggNog:ENOG410PKMK; InterPro:IPR000873,IPR025110,IPR020845; PFAM:PF00501,PF13193 AKAW2_70966S COG:I; EggNog:ENOG410Q2R4; InterPro:IPR033118,IPR007905; PFAM:PF05241; TransMembrane:5 (o28-51i63-84o116-140i147-167o187-207i); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0047750 - cholestenol delta-isomerase activity [Evidence IEA]; go_process: GO:0016125 - sterol metabolic process [Evidence IEA] AKAW2_70967A COG:C; EggNog:ENOG410PHVT; InterPro:IPR023210,IPR036812; PFAM:PF00248 AKAW2_70968A COG:S; EggNog:ENOG410Q5AU AKAW2_70969A COG:S; EggNog:ENOG410Q078 AKAW2_70970S COG:S; EggNog:ENOG410PRXS; InterPro:IPR011008,IPR009799; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA] AKAW2_70971S COG:G; EggNog:ENOG410PUYS; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i21-40o68-88i95-112o118-143i155-176o188-211i257-275o295- 314i326-343o349-370i382-404o416-436i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_70973S COG:G; EggNog:ENOG410PHNV; InterPro:IPR010720,IPR017853,IPR013780; PFAM:PF06964; SECRETED:SignalP(1-20); go_function: GO:0046556 - alpha-L-arabinofuranosidase activity [Evidence IEA]; go_process: GO:0046373 - L-arabinose metabolic process [Evidence IEA] AKAW2_70974S COG:Q; EggNog:ENOG410PVV3; InterPro:IPR036663; go_function: GO:0003824 - catalytic activity [Evidence IEA] AKAW2_70975A CAZy:CE16; COG:S; EggNog:ENOG410PK3Q; InterPro:IPR001087,IPR036514; PFAM:PF00657; SECRETED:SignalP(1-19); go_function: GO:0016788 - hydrolase activity, acting on ester bonds [Evidence IEA] AKAW2_70976A COG:O; EggNog:ENOG410PK5G AKAW2_70977A COG:O; EggNog:ENOG410PK5G; InterPro:IPR043129 AKAW2_70978S COG:S; EggNog:ENOG410Q28N AKAW2_70979S COG:U; EggNog:ENOG410Q2XK; InterPro:IPR020846,IPR001958,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i20-44o64-81i93-113o119-140i152-175o181-200i254-271o291- 311i318-335o355-382i403-424o430-450i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_70980S COG:S; EggNog:ENOG410PUFQ; InterPro:IPR036188,IPR002938; PFAM:PF01494; go_function: GO:0071949 - FAD binding [Evidence IEA] AKAW2_70981A COG:S; EggNog:ENOG410PU4H; SECRETED:SignalP(1-19) AKAW2_70982A COG:G; EggNog:ENOG410PVCS; InterPro:IPR020846,IPR005828,IPR036259; TransMembrane:5 (o6-25i32-53o73-99i111-130o142-161i); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_70983A COG:G; EggNog:ENOG410PVCS; InterPro:IPR020846,IPR005828,IPR036259; TransMembrane:3 (o20-39i51-73o79-99i); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_70984A COG:K; EggNog:ENOG410Q1KK; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_70985S COG:S; EggNog:ENOG410PV5R; InterPro:IPR036291,IPR008030; PFAM:PF05368,PF03435,PF01118,PF13460 AKAW2_70986A COG:S; EggNog:ENOG410PW9Y; InterPro:IPR036851,IPR000028; PFAM:PF01328; SECRETED:SignalP(1-17); go_function: GO:0004601 - peroxidase activity [Evidence IEA] AKAW2_70987S COG:S; EggNog:ENOG410PN7M; SECRETED:SignalP(1-21) AKAW2_70988S COG:M; EggNog:ENOG410PJJV; InterPro:IPR002110,IPR036770,IPR020683; PFAM:PF12796; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_70990S COG:M; EggNog:ENOG410Q1PV; InterPro:IPR002523; TransMembrane:2 (i12-35o47-65i); go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0046873 - metal ion transmembrane transporter activity [Evidence IEA]; go_process: GO:0030001 - metal ion transport [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_70991A COG:S; EggNog:ENOG410PIA3; InterPro:IPR011118,IPR029058; PFAM:PF07519; SECRETED:SignalP(1-19) AKAW2_70992A COG:S; EggNog:ENOG410Q22F AKAW2_70993A COG:S; EggNog:ENOG410PG0P; InterPro:IPR011118,IPR029058; PFAM:PF07519 AKAW2_70994A COG:G; EggNog:ENOG410PWP3; InterPro:IPR011042,IPR013658; PFAM:PF03088,PF08450 AKAW2_70995A COG:M; EggNog:ENOG410PJJV; InterPro:IPR002110,IPR020683,IPR001810,IPR036770; PFAM:PF13857,PF12796,PF00023,PF13637,PF13606; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_70996S SECRETED:SignalP(1-19) AKAW2_70997S COG:G; EggNog:ENOG410PW8D; InterPro:IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i42-66o86-105i112-131o137-158i170-190o196-222i243- 268o280-303i312-332o338-365i377-398o410-431i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_70998A CAZy:PL1; COG:G; EggNog:ENOG410PI0Z; InterPro:IPR012334,IPR002022,IPR011050; PFAM:PF00544; SECRETED:SignalP(1-20) AKAW2_70999S COG:Q; EggNog:ENOG410PIPS; InterPro:IPR026992,IPR027443,IPR005123; PFAM:PF03171,PF14226; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_71000A COG:C; EggNog:ENOG410PKTJ; InterPro:IPR015590,IPR016161,IPR016162,IPR016163; PFAM:PF00171; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0016620 - oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_71001S COG:S; EggNog:ENOG410PVBI; SECRETED:SignalP(1-19) AKAW2_71002A COG:S; EggNog:ENOG410PQI9; InterPro:IPR010699; PFAM:PF06912; TransMembrane:6 (i25-45o73-91i103-122o162-182i202-219o225-246i) AKAW2_71003S COG:C; EggNog:ENOG410QDJN; InterPro:IPR039556,IPR018523,IPR015813,IPR040442; PFAM:PF13714; TransMembrane:1 (o273-292i); go_function: GO:0003824 - catalytic activity [Evidence IEA] AKAW2_71004A COG:S; EggNog:ENOG410PY06; InterPro:IPR027843,IPR032710; PFAM:PF14534; TransMembrane:1 (o24-44i) AKAW2_71006S COG:F; EggNog:ENOG410PGQ0; InterPro:IPR009486; PFAM:PF06516; SECRETED:SignalP(1-24); go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_71007A COG:E; EggNog:ENOG410PKBT; InterPro:IPR013830,IPR036514; PFAM:PF00657,PF13472; SECRETED:SignalP(1-25) AKAW2_71008A COG:I; EggNog:ENOG410PHHA; InterPro:IPR019826,IPR002018,IPR029058; MEROPS:MER0030934; PFAM:PF00135; SECRETED:SignalP(1-23) AKAW2_71009A COG:F; EggNog:ENOG410PMUR; InterPro:IPR015943,IPR001680,IPR036322,IPR027417, IPR029058; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_71010S COG:F; EggNog:ENOG410QEB3; InterPro:IPR002125,IPR016193; PFAM:PF00383,PF18785; go_function: GO:0003824 - catalytic activity [Evidence IEA] AKAW2_71011A COG:G; EggNog:ENOG410QE24; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:14 (i47-64o84-103i115-137o143-165i177-199o205-226i247- 266o278-296i308-337o349-368i380-399o405-431i443-465o485- 506i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_71012S COG:G; EggNog:ENOG410PJ5Z; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i57-74o98-119i126-145o157-175i187-209o221-241i290- 314o326-346i353-373o379-404i416-437o449-472i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_71013A COG:C; EggNog:ENOG410PMYT; TransMembrane:1 (n4-16c21/22o31-52i) AKAW2_71014A COG:Q; EggNog:ENOG410PV61; InterPro:IPR001128,IPR017972,IPR002401,IPR036396; PFAM:PF00067; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_71015A COG:I; EggNog:ENOG410PVYH; InterPro:IPR032088,IPR003965,IPR029069,IPR039569, IPR001227,IPR014043,IPR002539,IPR040883,IPR016452, IPR016035,IPR013785,IPR013565; PFAM:PF17951,PF16073,PF01575,PF08354,PF00698, PF13452; go_component: GO:0005835 - fatty acid synthase complex [Evidence IEA]; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0004312 - fatty acid synthase activity [Evidence IEA]; go_function: GO:0004313 - [acyl-carrier-protein] S-acetyltransferase activity [Evidence IEA]; go_function: GO:0004314 - [acyl-carrier-protein] S-malonyltransferase activity [Evidence IEA]; go_function: GO:0004317 - 3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity [Evidence IEA]; go_function: GO:0004318 - enoyl-[acyl-carrier-protein] reductase (NADH) activity [Evidence IEA]; go_function: GO:0016740 - transferase activity [Evidence IEA]; go_process: GO:0006633 - fatty acid biosynthetic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_71016A COG:I; EggNog:ENOG410PUG3; InterPro:IPR016035,IPR041550,IPR016039,IPR036291, IPR018201,IPR026025,IPR014030,IPR014031,IPR040899; PFAM:PF18325,PF00109,PF02801,PF18314; go_component: GO:0005835 - fatty acid synthase complex [Evidence IEA]; go_function: GO:0004312 - fatty acid synthase activity [Evidence IEA]; go_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein] synthase activity [Evidence IEA]; go_function: GO:0004316 - 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity [Evidence IEA]; go_function: GO:0008897 - holo-[acyl-carrier-protein] synthase activity [Evidence IEA]; go_function: GO:0016746 - transferase activity, transferring acyl groups [Evidence IEA]; go_process: GO:0006633 - fatty acid biosynthetic process [Evidence IEA]; go_process: GO:0042759 - long-chain fatty acid biosynthetic process [Evidence IEA] AKAW2_71017A COG:E; EggNog:ENOG410PVTE; InterPro:IPR036038,IPR005786,IPR001544,IPR043131, IPR043132,IPR033939; PFAM:PF01063; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0004084 - branched-chain-amino-acid transaminase activity [Evidence IEA]; go_process: GO:0009081 - branched-chain amino acid metabolic process [Evidence IEA] AKAW2_71019S COG:Q; EggNog:ENOG410PIQ2; InterPro:IPR013154,IPR013149,IPR036291,IPR011032, IPR020843; PFAM:PF00107,PF08240,PF13602; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_71020A COG:S; EggNog:ENOG410QDZM; InterPro:IPR014710,IPR011051,IPR013096; PFAM:PF07883 AKAW2_71022A COG:T,Z; EggNog:ENOG410PM47; InterPro:IPR001781,IPR034962; PFAM:PF00412; go_process: GO:0035023 - regulation of Rho protein signal transduction [Evidence IEA] AKAW2_71023S COG:I; EggNog:ENOG410PGB6; InterPro:IPR036291,IPR013021,IPR002587; PFAM:PF01658,PF07994; go_function: GO:0004512 - inositol-3-phosphate synthase activity [Evidence IEA]; go_process: GO:0006021 - inositol biosynthetic process [Evidence IEA]; go_process: GO:0008654 - phospholipid biosynthetic process [Evidence IEA] AKAW2_71024A COG:E; EggNog:ENOG410PI5H; InterPro:IPR036052,IPR027278,IPR005965,IPR001926; PFAM:PF00291; go_function: GO:0008660 - 1-aminocyclopropane-1-carboxylate deaminase activity [Evidence IEA]; go_function: GO:0030170 - pyridoxal phosphate binding [Evidence IEA]; go_process: GO:0009310 - amine catabolic process [Evidence IEA] AKAW2_71025A BUSCO:EOG09262PIH; COG:Q; EggNog:ENOG410PVH9; InterPro:IPR013154,IPR013149,IPR002328,IPR036291, IPR014183,IPR011032,IPR020843; PFAM:PF00107,PF08240; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0051903 - S-(hydroxymethyl)glutathione dehydrogenase activity [Evidence IEA]; go_process: GO:0006069 - ethanol oxidation [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_71026A BUSCO:EOG09265L8N; COG:U; EggNog:ENOG410PQZ5; InterPro:IPR004217,IPR035427; PFAM:PF02953 AKAW2_71027S COG:T; EggNog:ENOG410PGBJ; InterPro:IPR000198,IPR008936; PFAM:PF00620; go_process: GO:0007165 - signal transduction [Evidence IEA] AKAW2_71028S COG:G; EggNog:ENOG410PMW8; InterPro:IPR009580; PFAM:PF06699; TransMembrane:4 (i167-190o196-217i237-258o264-286i); go_component: GO:0005789 - endoplasmic reticulum membrane [Evidence IEA]; go_process: GO:0006506 - GPI anchor biosynthetic process [Evidence IEA] AKAW2_71029A COG:S; EggNog:ENOG410PPP1 AKAW2_71030A BUSCO:EOG092617S2; COG:L; EggNog:ENOG410PFJA; InterPro:IPR041677,IPR027417,IPR003593,IPR041679, IPR014001; PFAM:PF13245,PF13086,PF13087,PF04851,PF13604; go_function: GO:0004386 - helicase activity [Evidence IEA] AKAW2_71031A COG:S; EggNog:ENOG410Q1PS; InterPro:IPR038883 AKAW2_71032A BUSCO:EOG09263R4M; COG:L; EggNog:ENOG410PIPF; InterPro:IPR003265,IPR000445,IPR004036,IPR023170, IPR011257,IPR030841; PFAM:PF00730,PF00633; go_component: GO:0005634 - nucleus [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0003906 - DNA-(apurinic or apyrimidinic site) endonuclease activity [Evidence IEA]; go_function: GO:0019104 - DNA N-glycosylase activity [Evidence IEA]; go_process: GO:0006281 - DNA repair [Evidence IEA]; go_process: GO:0006284 - base-excision repair [Evidence IEA]; go_process: GO:0006285 - base-excision repair, AP site formation [Evidence IEA] AKAW2_71033S COG:O; EggNog:ENOG410PQC3; InterPro:IPR016135,IPR023313,IPR000608; PFAM:PF00179 AKAW2_71034A COG:D; EggNog:ENOG410Q2EM; SECRETED:SignalP(1-22) AKAW2_71036A COG:S; EggNog:ENOG410PHHU; InterPro:IPR029675; PFAM:PF04666; TransMembrane:3 (i12-34o261-285i297-316o); go_component: GO:0000139 - Golgi membrane [Evidence IEA]; go_function: GO:0016757 - transferase activity, transferring glycosyl groups [Evidence IEA]; go_process: GO:0006506 - GPI anchor biosynthetic process [Evidence IEA] AKAW2_71037A TransMembrane:1 (o73-95i) AKAW2_71038S CAZy:GH72; COG:G; EggNog:ENOG410PHUW; InterPro:IPR017853,IPR004886; PFAM:PF00150,PF03198; SECRETED:SignalP(1-19); TransMembrane:1 (n3-14c19/20o435-457i) AKAW2_71039S CAZy:AA3; CAZy:AA8; COG:E; EggNog:ENOG410PHG9; InterPro:IPR036188,IPR038697,IPR000172,IPR015920, IPR007867; PFAM:PF00732,PF16010,PF05199; SECRETED:SignalP(1-20); go_function: GO:0016614 - oxidoreductase activity, acting on CH-OH group of donors [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_71040A COG:S; EggNog:ENOG410Q257; InterPro:IPR036395,IPR001083; PFAM:PF00649; go_component: GO:0005634 - nucleus [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0003700 - DNA-binding transcription factor activity [Evidence IEA]; go_function: GO:0005507 - copper ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_71041A BUSCO:EOG09260XMI; COG:Z; EggNog:ENOG410QDEW; InterPro:IPR001060,IPR027267,IPR035459,IPR036028, IPR002219,IPR031160,IPR020454,IPR001452; PFAM:PF14604,PF00018,PF00130,PF00611; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0035556 - intracellular signal transduction [Evidence IEA] AKAW2_71042S BUSCO:EOG09261MPU; COG:A; EggNog:ENOG410PGTJ; InterPro:IPR027417,IPR001650,IPR014014,IPR014001, IPR011545,IPR000629; PFAM:PF00270,PF00271; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0004386 - helicase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA] AKAW2_71044S COG:H; EggNog:ENOG410PG38; InterPro:IPR036144,IPR000926,IPR022163,IPR032677; PFAM:PF00925,PF12471; go_function: GO:0003935 - GTP cyclohydrolase II activity [Evidence IEA]; go_process: GO:0009231 - riboflavin biosynthetic process [Evidence IEA] AKAW2_71045A COG:S; EggNog:ENOG410PWSV; TransMembrane:7 (o15-36i43-62o94-115i127-148o187-204i216-238o258-282i) AKAW2_71046S COG:E; EggNog:ENOG410PM2D; InterPro:IPR002220,IPR013785; PFAM:PF00701; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0016829 - lyase activity [Evidence IEA] AKAW2_71047S COG:S; EggNog:ENOG410PHAA; InterPro:IPR010730; PFAM:PF06985 AKAW2_71048A COG:J; EggNog:ENOG410PND1; InterPro:IPR000182,IPR016181; PFAM:PF00583,PF13302; go_function: GO:0008080 - N-acetyltransferase activity [Evidence IEA] AKAW2_71049S COG:P,Q; EggNog:ENOG410PFX0; InterPro:IPR017938,IPR017927,IPR013130,IPR013121, IPR039261,IPR013112; PFAM:PF01794,PF08030; TransMembrane:7 (o16-34i102-123o135-153i174-191o211-229i241-261o267-289i); go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_71050A COG:G; EggNog:ENOG410PKEJ; InterPro:IPR005828,IPR036259; PFAM:PF00083; TransMembrane:6 (i62-85o97-117i124-146o152-178i190-208o220-241i); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_71051A COG:G; EggNog:ENOG410PKEJ; InterPro:IPR005829,IPR005828,IPR020846,IPR036259; TransMembrane:2 (i46-66o128-147i); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_71052A CAZy:CBM67; CAZy:GH78; COG:S; EggNog:ENOG410PKDA; InterPro:IPR008979,IPR035396,IPR008928,IPR012341; PFAM:PF17389; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_71053S TransMembrane:1 (o58-78i) AKAW2_71054S COG:T; EggNog:ENOG410PHA0; InterPro:IPR001789,IPR035965,IPR003594,IPR003661, IPR036890,IPR036097,IPR011006,IPR000014,IPR004358, IPR005467; PFAM:PF00072,PF00512,PF02518; go_function: GO:0000155 - phosphorelay sensor kinase activity [Evidence IEA]; go_function: GO:0016772 - transferase activity, transferring phosphorus-containing groups [Evidence IEA]; go_process: GO:0000160 - phosphorelay signal transduction system [Evidence IEA]; go_process: GO:0007165 - signal transduction [Evidence IEA]; go_process: GO:0016310 - phosphorylation [Evidence IEA] AKAW2_71055S COG:S; EggNog:ENOG410Q2GP; InterPro:IPR023213; TransMembrane:1 (o202-224i) AKAW2_71056S COG:S; EggNog:ENOG410Q2GP AKAW2_71057A COG:Q; EggNog:ENOG410PMA8; InterPro:IPR013154,IPR013149,IPR036291,IPR011032; PFAM:PF00107,PF08240; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_71059S COG:G; EggNog:ENOG410PVSV; InterPro:IPR013022,IPR036237; PFAM:PF01261 AKAW2_71060S SECRETED:SignalP(1-17) AKAW2_71061S COG:Q; EggNog:ENOG410PWGN; InterPro:IPR036291,IPR002347; PFAM:PF00106; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_71062S COG:Q; EggNog:ENOG410PKQ1; InterPro:IPR036396,IPR001128,IPR002401; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_71063A COG:S; EggNog:ENOG410Q1A8; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_71064A COG:S; EggNog:ENOG410PZTG; InterPro:IPR029068; PFAM:PF13669 AKAW2_71065A COG:O; EggNog:ENOG410PK6V; InterPro:IPR000641; go_function: GO:0005524 - ATP binding [Evidence IEA] AKAW2_71066A COG:O; EggNog:ENOG410PK6V; InterPro:IPR000641,IPR003959,IPR027417,IPR003593, IPR041679,IPR041627; PFAM:PF00004,PF13087,PF17866; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA] AKAW2_71067A COG:O; EggNog:ENOG410PK6V; InterPro:IPR027417,IPR041677; PFAM:PF13086,PF13245; go_function: GO:0004386 - helicase activity [Evidence IEA] AKAW2_71068S COG:S; EggNog:ENOG410PGSC AKAW2_71069S COG:Q; EggNog:ENOG410PM8C; InterPro:IPR001128,IPR002403,IPR036396; PFAM:PF00067; TransMembrane:1 (o214-233i); go_function: GO:0004497 - monooxygenase activity [Evidence IEA]; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_71070S COG:S; EggNog:ENOG410Q20I AKAW2_71071A CAZy:GH18; COG:G; EggNog:ENOG410PI86; InterPro:IPR011583,IPR029070,IPR001223,IPR017853, IPR001579; PFAM:PF00704; SECRETED:SignalP(1-22); TransMembrane:1 (o764-782i); go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_function: GO:0008061 - chitin binding [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_71072S COG:S; EggNog:ENOG410PKNM; InterPro:IPR012334,IPR011050,IPR024535; PFAM:PF12708; SECRETED:SignalP(1-23) AKAW2_71073S COG:S; EggNog:ENOG410PKNM; InterPro:IPR012334,IPR011050 AKAW2_71074S COG:S; EggNog:ENOG410PMEE; InterPro:IPR018392,IPR036779; PFAM:PF01476 AKAW2_71075S COG:S; EggNog:ENOG410PV45 AKAW2_71076S COG:S; EggNog:ENOG410PU1J AKAW2_71077A COG:G; EggNog:ENOG410PGQD; InterPro:IPR005829,IPR005828,IPR003663,IPR036259, IPR020846; PFAM:PF00083,PF07690; TransMembrane:12 (i63-81o115-134i146-164o170-191i203-226o232-254i324- 343o363-383i395-412o424-452i464-483o489-513i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_80001S COG:S; EggNog:ENOG410Q26M; InterPro:IPR014756,IPR014752 AKAW2_80002A COG:G; EggNog:ENOG410PFPE; InterPro:IPR029061,IPR020826,IPR033247,IPR009014, IPR005474,IPR005475; PFAM:PF02779,PF00456; go_function: GO:0003824 - catalytic activity [Evidence IEA] AKAW2_80003A COG:G; EggNog:ENOG410PFEN; InterPro:IPR005828,IPR003663,IPR036259,IPR020846; PFAM:PF00083,PF07690; TransMembrane:12 (i23-42o70-93i100-120o126-147i159-177o197-215i287-310o322- 342i354-377o383-409i421-442o448-469i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_80004S COG:G; EggNog:ENOG410PJKB; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:11 (o83-105i112-131o137-160i172-194o206-228i281-301o321- 338i347-369o375-395i407-424o436-461i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_80005S COG:Q; EggNog:ENOG410PMB4; InterPro:IPR036291,IPR002347; PFAM:PF08659,PF00106,PF13561; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_80006A COG:K; EggNog:ENOG410PUR1; InterPro:IPR036864,IPR021858,IPR001138; PFAM:PF00172,PF11951; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_80007A COG:Q; EggNog:ENOG410PFT4; InterPro:IPR002347,IPR036291; PFAM:PF00106,PF13561,PF08659,PF01370; SMCOG1001:short-chain dehydrogenase/reductase SDR; antiSMASH:Cluster_8.1; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_80008S COG:S; EggNog:ENOG410PXA4; TransMembrane:6 (o12-33i45-72o92-112i124-145o174-194i201-218o); antiSMASH:Cluster_8.1 AKAW2_80009S COG:S; EggNog:ENOG410PW4V; InterPro:IPR000073,IPR029058; PFAM:PF12697; antiSMASH:Cluster_8.1 AKAW2_80010A COG:S; EggNog:ENOG410PMB2; InterPro:IPR011009,IPR002575; TransMembrane:1 (o391-409i); antiSMASH:Cluster_8.1 AKAW2_80011A COG:U; EggNog:ENOG410PKHT; InterPro:IPR022812,IPR027417,IPR001401,IPR000375, IPR030381,IPR020850; PFAM:PF00350; antiSMASH:Cluster_8.1; go_function: GO:0003924 - GTPase activity [Evidence IEA]; go_function: GO:0005525 - GTP binding [Evidence IEA] AKAW2_80012A SECRETED:SignalP(1-17); antiSMASH:Cluster_8.1 AKAW2_80013S COG:S; EggNog:ENOG410Q02D; SECRETED:SignalP(1-19); antiSMASH:Cluster_8.1 AKAW2_80014A COG:I; EggNog:ENOG410PJB7; InterPro:IPR000873,IPR020845,IPR009081,IPR029063, IPR036736,IPR029058,IPR020806,IPR010071,IPR042099, IPR023213,IPR001242; PFAM:PF00501,PF00668,PF00550; SMCOG1002:AMP-dependent synthetase and ligase; antiSMASH:Cluster_8.1; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0031177 - phosphopantetheine binding [Evidence IEA] AKAW2_80015A COG:I; EggNog:ENOG410PJB7; InterPro:IPR042099,IPR000873,IPR020845; PFAM:PF00501; SMCOG1002:AMP-dependent synthetase and ligase; antiSMASH:Cluster_8.1 AKAW2_80016A COG:S; EggNog:ENOG410PQ8Y; TransMembrane:7 (o30-53i65-86o115-132i144-170o190-211i223-245o265-282i); antiSMASH:Cluster_8.1 AKAW2_80017S COG:S; EggNog:ENOG410PPYX; InterPro:IPR001077,IPR036388,IPR016461,IPR029063, IPR036390; PFAM:PF00891; SMCOG1042:O-methyltransferase; antiSMASH:Cluster_8.1; go_function: GO:0008168 - methyltransferase activity [Evidence IEA]; go_function: GO:0008171 - O-methyltransferase activity [Evidence IEA] AKAW2_80018A COG:S; EggNog:ENOG410PN1U; TransMembrane:7 (o12-31i43-64o84-109i121-143o171-191i203-223o243-265i); antiSMASH:Cluster_8.1 AKAW2_80019A antiSMASH:Cluster_8.1 AKAW2_80020A COG:S; EggNog:ENOG410PID4; TransMembrane:7 (o6-29i41-63o83-106i118-139o165-188i200-222o228-251i); antiSMASH:Cluster_8.1 AKAW2_80021A CAZy:CE10; COG:T; EggNog:ENOG410PM9K; InterPro:IPR019826,IPR002018,IPR029058; MEROPS:MER0033198; PFAM:PF00135; SECRETED:SignalP(1-27) AKAW2_80022A CAZy:CE5; COG:G; EggNog:ENOG410PMSQ; InterPro:IPR011150,IPR043579,IPR029058,IPR000675; PFAM:PF01083; go_component: GO:0005576 - extracellular region [Evidence IEA]; go_function: GO:0016787 - hydrolase activity [Evidence IEA]; go_function: GO:0050525 - cutinase activity [Evidence IEA] AKAW2_80023A COG:G; EggNog:ENOG410PJKY; InterPro:IPR005828,IPR003663,IPR036259,IPR020846; PFAM:PF00083,PF07690; TransMembrane:11 (o15-33i97-114o120-144i156-174o186-209i282-303o309- 326i338-357o369-393i405-428o440-458i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_80024S COG:I; EggNog:ENOG410PNQG; InterPro:IPR019826,IPR002018,IPR029058; MEROPS:MER0030934; PFAM:PF00135 AKAW2_80025A COG:K; EggNog:ENOG410QCDH; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; TransMembrane:1 (o479-499i); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_80026A COG:S; EggNog:ENOG410PR7T; InterPro:IPR000073,IPR029058; PFAM:PF12697 AKAW2_80029A COG:Q; EggNog:ENOG410PWA3; InterPro:IPR004294; PFAM:PF03055; go_function: GO:0016702 - oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_80030S COG:G; EggNog:ENOG410PVCX; TransMembrane:1 (o48-70i) AKAW2_80033S COG:G; EggNog:ENOG410PVCX; InterPro:IPR020846,IPR005828,IPR036259,IPR003663; TransMembrane:4 (i12-31o43-71i83-102o114-132i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_80034S CAZy:GH3; COG:G; EggNog:ENOG410PJ4A; InterPro:IPR017853,IPR036962,IPR002772,IPR036881, IPR026891,IPR013783,IPR001764; PFAM:PF14310,PF00933,PF01915; go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_80036S COG:Q; EggNog:ENOG410PFFP; InterPro:IPR020946,IPR036188; PFAM:PF07992,PF13738,PF13450; go_function: GO:0004499 - N,N-dimethylaniline monooxygenase activity [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_function: GO:0050661 - NADP binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_80037S COG:P,Q; EggNog:ENOG410PHSN; InterPro:IPR017927,IPR013130,IPR013121,IPR039261; PFAM:PF01794,PF08030; SECRETED:SignalP(1-18); TransMembrane:7 (n2-13c18/19o156-178i235-257o291-313i320-341o353-372i384- 404o410-427i); go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_80038A COG:S; EggNog:ENOG410PXY0; InterPro:IPR036291 AKAW2_80039S SECRETED:SignalP(1-18) AKAW2_80040S COG:S; EggNog:ENOG410PNBP; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_80041A COG:G; EggNog:ENOG410PW2X; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i64-87o99-117i129-146o158-176i188-205o217-236i290- 315o327-348i369-390o402-423i435-452o464-487i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_80042S CAZy:PL4; COG:G; EggNog:ENOG410PIS3; InterPro:IPR008979,IPR011013,IPR013784,IPR029413, IPR029411; PFAM:PF14686,PF14683; SECRETED:SignalP(1-19); go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0030246 - carbohydrate binding [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_80043S COG:I; EggNog:ENOG410PKJP; InterPro:IPR006091,IPR006089,IPR001199,IPR009075, IPR037069,IPR009100,IPR036400,IPR018506,IPR036250, IPR013786; PFAM:PF02770,PF00173,PF00441,PF02771; go_function: GO:0003995 - acyl-CoA dehydrogenase activity [Evidence IEA]; go_function: GO:0016627 - oxidoreductase activity, acting on the CH-CH group of donors [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_80044S COG:S; EggNog:ENOG410PJHU; InterPro:IPR021625,IPR013886; PFAM:PF08577,PF11566 AKAW2_80045S COG:T; EggNog:ENOG410PG4N; InterPro:IPR004843,IPR029052,IPR006186; PFAM:PF00149; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_80046A COG:E; EggNog:ENOG410PJFH; InterPro:IPR014710,IPR011051,IPR005708; PFAM:PF04209; go_function: GO:0004411 - homogentisate 1,2-dioxygenase activity [Evidence IEA]; go_process: GO:0006559 - L-phenylalanine catabolic process [Evidence IEA]; go_process: GO:0006570 - tyrosine metabolic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_80047A COG:I; EggNog:ENOG410PNQG; InterPro:IPR019826,IPR002018,IPR029058; MEROPS:MER0030934 AKAW2_80048A COG:U; EggNog:ENOG410PJXX; InterPro:IPR020846,IPR001958,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:11 (i29-52o72-93i100-125o131-149i161-181o187-208i296-317o355- 374i386-407o432-455i467-489o); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_80049A BUSCO:EOG09261IEV; COG:O; EggNog:ENOG410PH8H; InterPro:IPR035985,IPR000594,IPR030667; PFAM:PF00899; go_function: GO:0008641 - ubiquitin-like modifier activating enzyme activity [Evidence IEA]; go_function: GO:0019781 - NEDD8 activating enzyme activity [Evidence IEA]; go_process: GO:0045116 - protein neddylation [Evidence IEA] AKAW2_80050S BUSCO:EOG092641UM; COG:G; EggNog:ENOG410PGR7; InterPro:IPR004788,IPR037171; PFAM:PF06026; go_function: GO:0004751 - ribose-5-phosphate isomerase activity [Evidence IEA]; go_process: GO:0009052 - pentose-phosphate shunt, non-oxidative branch [Evidence IEA] AKAW2_80051A COG:D; EggNog:ENOG410PF93; InterPro:IPR015943,IPR001680,IPR036322,IPR017986; PFAM:PF00400; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_80052S COG:S; EggNog:ENOG410PG72; InterPro:IPR004130,IPR027417,IPR030231; PFAM:PF03029 AKAW2_80053A COG:J; EggNog:ENOG410PSB4; InterPro:IPR038085,IPR002759; PFAM:PF01900; go_function: GO:0004540 - ribonuclease activity [Evidence IEA]; go_process: GO:0008033 - tRNA processing [Evidence IEA] AKAW2_80054A COG:C; EggNog:ENOG410PGNT; InterPro:IPR017440,IPR016102,IPR002020,IPR017866, IPR005811,IPR036969,IPR036291,IPR033847,IPR016142, IPR016143,IPR003781; PFAM:PF00285,PF02629,PF00549; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0046912 - transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer [Evidence IEA] AKAW2_80055S COG:C; EggNog:ENOG410PH8Y; InterPro:IPR016102,IPR013650,IPR032263; PFAM:PF16114,PF08442 AKAW2_80056A BUSCO:EOG09265H9T; COG:O; EggNog:ENOG410PPNQ; InterPro:IPR018369,IPR020818,IPR011032,IPR037124; PFAM:PF00166; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006457 - protein folding [Evidence IEA] AKAW2_80057A BUSCO:EOG09264OAU; COG:A; EggNog:ENOG410PQ13; InterPro:IPR007854; PFAM:PF05182 AKAW2_80058S COG:S; EggNog:ENOG410PGV7; InterPro:IPR007005; PFAM:PF04921; go_component: GO:0005634 - nucleus [Evidence IEA] AKAW2_80059A COG:S; EggNog:ENOG410PPW9 AKAW2_80060A COG:I; EggNog:ENOG410PHDX; InterPro:IPR042098,IPR003819; PFAM:PF02668; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_80061A COG:U; EggNog:ENOG410PQGG; InterPro:IPR024882,IPR025574; PFAM:PF13634; go_component: GO:0005643 - nuclear pore [Evidence IEA]; go_function: GO:0008139 - nuclear localization sequence binding [Evidence IEA]; go_function: GO:0017056 - structural constituent of nuclear pore [Evidence IEA]; go_process: GO:0006913 - nucleocytoplasmic transport [Evidence IEA] AKAW2_80062S COG:T; EggNog:ENOG410PKWS; InterPro:IPR015943,IPR036322; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_80063S COG:S; EggNog:ENOG410PTUJ AKAW2_80064A COG:S; EggNog:ENOG410PJFG; InterPro:IPR041492,IPR006439,IPR023198,IPR036412, IPR023214; PFAM:PF00702,PF13419; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_80065S COG:S; EggNog:ENOG410PN21; InterPro:IPR011990,IPR019734; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_80066S COG:I; EggNog:ENOG410PNQG; InterPro:IPR019826,IPR002018,IPR029058; MEROPS:MER0030934; PFAM:PF00135,PF07859 AKAW2_80068A COG:G; EggNog:ENOG410QE5R; InterPro:IPR004843,IPR011160,IPR041805; PFAM:PF00149; SECRETED:SignalP(1-18); go_function: GO:0004767 - sphingomyelin phosphodiesterase activity [Evidence IEA]; go_function: GO:0016787 - hydrolase activity [Evidence IEA]; go_process: GO:0006685 - sphingomyelin catabolic process [Evidence IEA] AKAW2_80070A CAZy:GT1; COG:C,G; EggNog:ENOG410PWGV; InterPro:IPR002213,IPR004276; PFAM:PF03033; go_function: GO:0008194 - UDP-glycosyltransferase activity [Evidence IEA]; go_function: GO:0016758 - transferase activity, transferring hexosyl groups [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA]; go_process: GO:0030259 - lipid glycosylation [Evidence IEA] AKAW2_80071S COG:S; EggNog:ENOG410PHZ2; InterPro:IPR013083; PFAM:PF13920; TransMembrane:5 (n7-18c36/37o130-149i170-188o355-375i387-404o424-450i) AKAW2_80073A COG:S; EggNog:ENOG410PTHB; InterPro:IPR008427; PFAM:PF05730; SECRETED:SignalP(1-18) AKAW2_80074A COG:L; EggNog:ENOG410PT89; InterPro:IPR007218; PFAM:PF04081; go_process: GO:0000731 - DNA synthesis involved in DNA repair [Evidence IEA]; go_process: GO:0006260 - DNA replication [Evidence IEA] AKAW2_80075S COG:S; EggNog:ENOG410PF9M; InterPro:IPR011022; PFAM:PF02752 AKAW2_80077S BUSCO:EOG09263AZP; COG:J; EggNog:ENOG410PNWX; InterPro:IPR024336,IPR024337; PFAM:PF12928 AKAW2_80078A BUSCO:EOG09265QTV; COG:K; EggNog:ENOG410PQMI; InterPro:IPR016073,IPR001232,IPR011333,IPR039948; PFAM:PF03931; go_process: GO:0006511 - ubiquitin-dependent protein catabolic process [Evidence IEA] AKAW2_80079S COG:Q; EggNog:ENOG410PQQ9; InterPro:IPR036291,IPR002347,IPR020904; PFAM:PF08659,PF13561; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_80080A COG:O; EggNog:ENOG410PFVA; InterPro:IPR019572,IPR035985,IPR000594,IPR028077, IPR030661,IPR033127,IPR023318; PFAM:PF14732,PF00899; go_function: GO:0008641 - ubiquitin-like modifier activating enzyme activity [Evidence IEA]; go_function: GO:0019948 - SUMO activating enzyme activity [Evidence IEA]; go_process: GO:0016925 - protein sumoylation [Evidence IEA] AKAW2_80081S COG:H; EggNog:ENOG410PIF4; InterPro:IPR019438; PFAM:PF10343 AKAW2_80082A COG:L; EggNog:ENOG410PQJ2; InterPro:IPR008721; PFAM:PF05460; go_component: GO:0005664 - nuclear origin of replication recognition complex [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_process: GO:0006260 - DNA replication [Evidence IEA] AKAW2_80083S COG:O; EggNog:ENOG410PN0B; InterPro:IPR024936,IPR029000,IPR020892,IPR002130; PFAM:PF00160; go_function: GO:0003755 - peptidyl-prolyl cis-trans isomerase activity [Evidence IEA]; go_process: GO:0000413 - protein peptidyl-prolyl isomerization [Evidence IEA]; go_process: GO:0006457 - protein folding [Evidence IEA] AKAW2_80084A BUSCO:EOG09262Z0M; COG:S; EggNog:ENOG410PIY4; InterPro:IPR042451,IPR040141,IPR042452,IPR004457; PFAM:PF03367; go_function: GO:0008270 - zinc ion binding [Evidence IEA] AKAW2_80085A COG:K; EggNog:ENOG410PQ7B; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_80086S BUSCO:EOG09260RNZ; COG:S; EggNog:ENOG410PKWD; InterPro:IPR019451,IPR016024,IPR039600,IPR019414; PFAM:PF10363,PF10304 AKAW2_80087A BUSCO:EOG09262LI4; COG:A; EggNog:ENOG410PGPY; InterPro:IPR007708; PFAM:PF05011; go_function: GO:0016788 - hydrolase activity, acting on ester bonds [Evidence IEA]; go_process: GO:0006397 - mRNA processing [Evidence IEA] AKAW2_80088S COG:S; EggNog:ENOG410Q0S6; InterPro:IPR007175; PFAM:PF04032 AKAW2_80089S COG:O; EggNog:ENOG410PJYG; InterPro:IPR016024,IPR013932,IPR039852; PFAM:PF08623; go_process: GO:0010265 - SCF complex assembly [Evidence IEA] AKAW2_80090A COG:T; EggNog:ENOG410PGBT; InterPro:IPR001611,IPR003591,IPR032675,IPR025875; PFAM:PF12799,PF13855; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_80091A COG:S; EggNog:ENOG410PZ1J; TransMembrane:1 (o49-67i) AKAW2_80092S COG:O; EggNog:ENOG410PMPS; InterPro:IPR016024,IPR011989,IPR039852; go_process: GO:0010265 - SCF complex assembly [Evidence IEA] AKAW2_80093S CAZy:CE4; COG:G; EggNog:ENOG410PGMP; InterPro:IPR036861,IPR011330,IPR002509,IPR001002; PFAM:PF00187,PF01522; SECRETED:SignalP(1-19); TransMembrane:1 (n6-14c19/20o419-438i); go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0008061 - chitin binding [Evidence IEA]; go_function: GO:0016810 - hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_80094A COG:S; EggNog:ENOG410PZ4B AKAW2_80095A BUSCO:EOG09260FZZ; COG:U; EggNog:ENOG410PI91; InterPro:IPR016024,IPR013026,IPR019734,IPR036322, IPR016528,IPR011990,IPR000547; PFAM:PF00637; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0006886 - intracellular protein transport [Evidence IEA]; go_process: GO:0016192 - vesicle-mediated transport [Evidence IEA] AKAW2_80096S COG:T; EggNog:ENOG410PUCU; InterPro:IPR000719,IPR011009,IPR017441; PFAM:PF00069; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_80097S COG:S; EggNog:ENOG410Q2TG AKAW2_80098A COG:S; EggNog:ENOG410PU4N AKAW2_80099S COG:U; EggNog:ENOG410PHZ0; InterPro:IPR013599,IPR016439,IPR006634; PFAM:PF08390,PF03798; TransMembrane:7 (i56-78o114-131i158-176o203-221i233-261o281-298i336-360o); go_component: GO:0016021 - integral component of membrane [Evidence IEA] AKAW2_80100A COG:T; EggNog:ENOG410Q183; InterPro:IPR001789,IPR035965,IPR003594,IPR003661, IPR036890,IPR036097,IPR011006,IPR000700,IPR000014, IPR004358,IPR005467; PFAM:PF13426,PF00072,PF00512,PF02518,PF08448, PF00989; go_function: GO:0000155 - phosphorelay sensor kinase activity [Evidence IEA]; go_function: GO:0016772 - transferase activity, transferring phosphorus-containing groups [Evidence IEA]; go_process: GO:0000160 - phosphorelay signal transduction system [Evidence IEA]; go_process: GO:0007165 - signal transduction [Evidence IEA]; go_process: GO:0016310 - phosphorylation [Evidence IEA] AKAW2_80101S COG:T; EggNog:ENOG410PFPV; InterPro:IPR004813,IPR004648; PFAM:PF03169; TransMembrane:14 (o69-89i96-117o137-158i170-193o199-219i231-264o303- 326i377-399o430-451i458-480o542-564i611-630o650-673i685- 711o); go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_80102S COG:K; EggNog:ENOG410PUUR; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; TransMembrane:1 (o572-592i); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_80103S COG:F; EggNog:ENOG410PG2G; InterPro:IPR011059,IPR006680,IPR032466,IPR014311; MEROPS:MER0037714; PFAM:PF01979; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_function: GO:0008892 - guanine deaminase activity [Evidence IEA]; go_function: GO:0016787 - hydrolase activity [Evidence IEA]; go_function: GO:0016810 - hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [Evidence IEA]; go_process: GO:0006147 - guanine catabolic process [Evidence IEA] AKAW2_80104S COG:O; EggNog:ENOG410PMA6; InterPro:IPR038765,IPR002931; MEROPS:MER0472834; PFAM:PF01841 AKAW2_80105S COG:G; EggNog:ENOG410PJ41; InterPro:IPR005829,IPR005828,IPR003663,IPR036259, IPR020846; PFAM:PF00083,PF07690; TransMembrane:11 (o6-24i93-114o120-139i151-171o183-203i273-293o313-329i338- 359o385-409i421-440o452-470i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_80106S COG:O; EggNog:ENOG410PHFF; InterPro:IPR036852,IPR015366,IPR030400; MEROPS:MER0005329; PFAM:PF09286; SECRETED:SignalP(1-15); go_function: GO:0004252 - serine-type endopeptidase activity [Evidence IEA]; go_function: GO:0008236 - serine-type peptidase activity [Evidence IEA]; go_process: GO:0006508 - proteolysis [Evidence IEA] AKAW2_80108A COG:C; EggNog:ENOG410PFVQ; InterPro:IPR020471,IPR036812,IPR023210; PFAM:PF00248; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_80110S COG:S; EggNog:ENOG410PVPM; InterPro:IPR021838; PFAM:PF11913 AKAW2_80111A COG:S; EggNog:ENOG410Q0IW; SECRETED:SignalP(1-37); TransMembrane:1 (n21-32c37/38o259-280i) AKAW2_80112A COG:S; EggNog:ENOG410PFGS; InterPro:IPR011118,IPR029058; PFAM:PF07519; SECRETED:SignalP(1-21) AKAW2_80113A CAZy:GH76; COG:G; EggNog:ENOG410PFRH; InterPro:IPR005198,IPR008928,IPR014480; PFAM:PF03663; SECRETED:SignalP(1-23); TransMembrane:1 (n9-19c23/24o448-470i); go_function: GO:0008496 - mannan endo-1,6-alpha-mannosidase activity [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA]; go_process: GO:0016052 - carbohydrate catabolic process [Evidence IEA] AKAW2_80114S COG:T; EggNog:ENOG410PY4K; InterPro:IPR000719,IPR011009,IPR008271; PFAM:PF07714,PF00069; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_80115A COG:S; EggNog:ENOG410PX4Y; InterPro:IPR002523; TransMembrane:2 (i46-68o88-112i); go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0046873 - metal ion transmembrane transporter activity [Evidence IEA]; go_process: GO:0030001 - metal ion transport [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_80117S COG:E; EggNog:ENOG410QDM6; InterPro:IPR004840,IPR004841; PFAM:PF13520,PF03845,PF00324; TransMembrane:11 (o15-34i41-63o99-119i131-152o158-178i235-255o302-322i356- 377o389-413i449-470o482-499i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_process: GO:0006865 - amino acid transport [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_80119A BUSCO:EOG09262DC1; COG:S; EggNog:ENOG410PF98; InterPro:IPR036322,IPR015943,IPR001680,IPR019775, IPR020472,IPR022052,IPR017986; PFAM:PF12265,PF00400; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_80120S BUSCO:EOG092644X6; COG:S; EggNog:ENOG410PG6J; InterPro:IPR005225,IPR001806,IPR017231,IPR027417; PFAM:PF04670,PF00025,PF08477,PF00071; go_function: GO:0003924 - GTPase activity [Evidence IEA]; go_function: GO:0005525 - GTP binding [Evidence IEA] AKAW2_80121A COG:S; EggNog:ENOG410PIY2; InterPro:IPR011009,IPR002575; PFAM:PF01636 AKAW2_80122S COG:S; EggNog:ENOG410PRH7; InterPro:IPR011057,IPR006913; PFAM:PF04828; go_function: GO:0016846 - carbon-sulfur lyase activity [Evidence IEA] AKAW2_80123S COG:G,M; EggNog:ENOG410PKEI; InterPro:IPR036291,IPR008030; PFAM:PF13460,PF05368 AKAW2_80124A COG:T; EggNog:ENOG410PFS3; InterPro:IPR000719,IPR011009,IPR008271; PFAM:PF07714,PF00069; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_80125S COG:S; EggNog:ENOG410PHZP AKAW2_80126S COG:S; EggNog:ENOG410Q2WJ AKAW2_80127S COG:C; EggNog:ENOG410PM3V; InterPro:IPR006140,IPR036291,IPR006139,IPR029753; PFAM:PF00389,PF02826; go_function: GO:0016616 - oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Evidence IEA]; go_function: GO:0051287 - NAD binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_80128S COG:S; EggNog:ENOG410PNZM; InterPro:IPR001214; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_80129S COG:F; EggNog:ENOG410PK7I; InterPro:IPR011059,IPR006680,IPR032466; PFAM:PF01979; go_function: GO:0016787 - hydrolase activity [Evidence IEA]; go_function: GO:0016810 - hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [Evidence IEA] AKAW2_80130S COG:S; EggNog:ENOG410PR3H AKAW2_80131A COG:S; EggNog:ENOG410Q2VT AKAW2_80132A COG:S; EggNog:ENOG410Q2CS; InterPro:IPR036864,IPR001138; PFAM:PF00172; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_80133A COG:S; EggNog:ENOG410PHGI; InterPro:IPR018996,IPR025856,IPR041885; PFAM:PF12949,PF09402; TransMembrane:2 (o345-362i557-576o) AKAW2_80134A COG:T; EggNog:ENOG410PGS1; InterPro:IPR001054,IPR036457,IPR001611,IPR000159, IPR029787,IPR001932,IPR003591,IPR013716,IPR032675; PFAM:PF00481,PF00211,PF13855,PF08509; go_function: GO:0000287 - magnesium ion binding [Evidence IEA]; go_function: GO:0004016 - adenylate cyclase activity [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_function: GO:0016791 - phosphatase activity [Evidence IEA]; go_process: GO:0006171 - cAMP biosynthetic process [Evidence IEA]; go_process: GO:0007165 - signal transduction [Evidence IEA]; go_process: GO:0009190 - cyclic nucleotide biosynthetic process [Evidence IEA]; go_process: GO:0035556 - intracellular signal transduction [Evidence IEA] AKAW2_80135S CAZy:GH16; COG:G; EggNog:ENOG410PFK0; InterPro:IPR000757,IPR013320,IPR017168; PFAM:PF00722; SECRETED:SignalP(1-21); go_component: GO:0005618 - cell wall [Evidence IEA]; go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_function: GO:0016798 - hydrolase activity, acting on glycosyl bonds [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA]; go_process: GO:0071555 - cell wall organization [Evidence IEA] AKAW2_80136A COG:Q; EggNog:ENOG410PGK3; InterPro:IPR001128,IPR017972,IPR002401,IPR036396; PFAM:PF00067; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_80137S COG:H; EggNog:ENOG410QE5T; InterPro:IPR040366; PFAM:PF14608; go_function: GO:0008143 - poly(A) binding [Evidence IEA]; go_process: GO:0043488 - regulation of mRNA stability [Evidence IEA]; go_process: GO:1900364 - negative regulation of mRNA polyadenylation [Evidence IEA] AKAW2_80138S BUSCO:EOG092621GY; COG:H; EggNog:ENOG410PH5T; InterPro:IPR002937,IPR004572,IPR036188; PFAM:PF01593,PF13450; go_function: GO:0004729 - oxygen-dependent protoporphyrinogen oxidase activity [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0006779 - porphyrin-containing compound biosynthetic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_80139A COG:A; EggNog:ENOG410PNAY; InterPro:IPR015362,IPR036348,IPR039333; PFAM:PF09282; go_process: GO:1903259 - exon-exon junction complex disassembly [Evidence IEA] AKAW2_80140S COG:C; EggNog:ENOG410PTB6; InterPro:IPR008027,IPR036656; PFAM:PF05365; go_component: GO:0005743 - mitochondrial inner membrane [Evidence IEA]; go_component: GO:0005750 - mitochondrial respiratory chain complex III [Evidence IEA]; go_process: GO:0006122 - mitochondrial electron transport, ubiquinol to cytochrome c [Evidence IEA] AKAW2_80141S COG:O; EggNog:ENOG410PFEZ; InterPro:IPR036390,IPR003126,IPR044046,IPR039164; PFAM:PF02207,PF18995; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_function: GO:0061630 - ubiquitin protein ligase activity [Evidence IEA]; go_process: GO:0071596 - ubiquitin-dependent protein catabolic process via the N-end rule pathway [Evidence IEA] AKAW2_80142S COG:H; EggNog:ENOG410PF94; InterPro:IPR027495,IPR036188,IPR002922; PFAM:PF01946,PF13450; go_process: GO:0009228 - thiamine biosynthetic process [Evidence IEA] AKAW2_80143A BUSCO:EOG09263A64; COG:T; EggNog:ENOG410PMCN; InterPro:IPR036691,IPR005135,IPR038772; PFAM:PF03372; TransMembrane:2 (i393-413o419-445i); go_function: GO:0004767 - sphingomyelin phosphodiesterase activity [Evidence IEA] AKAW2_80144S COG:S; EggNog:ENOG410PIXX; InterPro:IPR036322,IPR015943,IPR001680,IPR019775, IPR020472,IPR017986; PFAM:PF00400; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_80145S InterPro:IPR029032 AKAW2_80146A CAZy:GH128; COG:S; EggNog:ENOG410PPKI; InterPro:IPR017853,IPR024655; PFAM:PF11790; SECRETED:SignalP(1-26) AKAW2_80147A COG:F,P; EggNog:ENOG410PF8N; InterPro:IPR003695,IPR043129; PFAM:PF02541 AKAW2_80148A COG:G; EggNog:ENOG410QDIG; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i69-87o107-127i134-153o165-184i196-215o227-247i296- 316o336-353i360-379o385-409i421-442o448-473i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_80149S COG:S; EggNog:ENOG410PM23; InterPro:IPR013859; PFAM:PF08549 AKAW2_80150S COG:S; EggNog:ENOG410PJD9 AKAW2_80151S COG:S; EggNog:ENOG410PJD9; InterPro:IPR028245,IPR027267; PFAM:PF13805 AKAW2_80152S COG:O; EggNog:ENOG410PFGV; InterPro:IPR029055,IPR001353,IPR000243,IPR023333; MEROPS:MER0001516; go_component: GO:0005839 - proteasome core complex [Evidence IEA]; go_function: GO:0004298 - threonine-type endopeptidase activity [Evidence IEA]; go_process: GO:0051603 - proteolysis involved in cellular protein catabolic process [Evidence IEA] AKAW2_80153A COG:K; EggNog:ENOG410PFMF; InterPro:IPR007120,IPR007121,IPR037034,IPR037033, IPR015712,IPR014724,IPR007642,IPR007641,IPR009674, IPR007645,IPR007644; PFAM:PF04561,PF00562,PF04563,PF04565,PF04560, PF06883; go_component: GO:0005634 - nucleus [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0003899 - DNA-directed 5'-3' RNA polymerase activity [Evidence IEA]; go_function: GO:0032549 - ribonucleoside binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA] AKAW2_80154S COG:U; EggNog:ENOG410PI9F; InterPro:IPR005225,IPR027417,IPR044154,IPR006689; PFAM:PF04670,PF00025,PF08477,PF00071,PF01926, PF09439; go_function: GO:0003924 - GTPase activity [Evidence IEA]; go_function: GO:0005525 - GTP binding [Evidence IEA]; go_process: GO:0015031 - protein transport [Evidence IEA] AKAW2_80155S COG:S; EggNog:ENOG410PS24; InterPro:IPR020999; PFAM:PF12273; TransMembrane:1 (o30-52i) AKAW2_80156S COG:S; EggNog:ENOG410PT09; InterPro:IPR037504; TransMembrane:1 (i41-65o) AKAW2_80157A BUSCO:EOG09262HKC; COG:S; EggNog:ENOG410PGZ6; InterPro:IPR040194,IPR006768,IPR006767; PFAM:PF04677,PF04676 AKAW2_80158S BUSCO:EOG092600S9; COG:V; EggNog:ENOG410PGFK; InterPro:IPR016024,IPR011430; PFAM:PF07539 AKAW2_80159A BUSCO:EOG092658X5; COG:S; EggNog:ENOG410PPMN; InterPro:IPR024158,IPR007853; PFAM:PF05180; go_function: GO:0008270 - zinc ion binding [Evidence IEA] AKAW2_80160S COG:O; EggNog:ENOG410PFEU; InterPro:IPR036317,IPR036388,IPR001373,IPR036390, IPR019559,IPR016159,IPR016158,IPR016157; PFAM:PF10557,PF00888; go_component: GO:0031461 - cullin-RING ubiquitin ligase complex [Evidence IEA]; go_function: GO:0031625 - ubiquitin protein ligase binding [Evidence IEA]; go_process: GO:0006511 - ubiquitin-dependent protein catabolic process [Evidence IEA] AKAW2_80161A BUSCO:EOG09264VZ7; COG:L; EggNog:ENOG410PMSF; InterPro:IPR031633,IPR038749,IPR021151,IPR036224, IPR008591; PFAM:PF05916,PF16922; go_process: GO:0006261 - DNA-dependent DNA replication [Evidence IEA] AKAW2_80162A BUSCO:EOG09262FE3; COG:D; EggNog:ENOG410PI8H; InterPro:IPR001763,IPR000751,IPR036873; PFAM:PF00581; go_function: GO:0004725 - protein tyrosine phosphatase activity [Evidence IEA]; go_process: GO:0006470 - protein dephosphorylation [Evidence IEA]; go_process: GO:1902751 - positive regulation of cell cycle G2/M phase transition [Evidence IEA] AKAW2_80163A COG:M; EggNog:ENOG410PKKZ; InterPro:IPR002110,IPR036770,IPR020683; PFAM:PF13857,PF12796,PF00023,PF13637,PF13606; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_80164S BUSCO:EOG09260M44; COG:L; EggNog:ENOG410PFQC; InterPro:IPR016024,IPR007015; PFAM:PF04931; go_component: GO:0005730 - nucleolus [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008134 - transcription factor binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_80165A COG:S; EggNog:ENOG410PM3D; InterPro:IPR005302,IPR005303,IPR011037; PFAM:PF03476,PF03473; SECRETED:SignalP(1-27); go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0030151 - molybdenum ion binding [Evidence IEA]; go_function: GO:0030170 - pyridoxal phosphate binding [Evidence IEA] AKAW2_80166A COG:S; EggNog:ENOG410PPM8; InterPro:IPR036440,IPR016125; MEROPS:MER0011032 AKAW2_80167S COG:Q; EggNog:ENOG410PUA7; InterPro:IPR001128,IPR002403,IPR017972,IPR036396; PFAM:PF00067; TransMembrane:1 (o12-30i); go_function: GO:0004497 - monooxygenase activity [Evidence IEA]; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_80168S COG:S; EggNog:ENOG410PQB2 AKAW2_80169A COG:D; EggNog:ENOG410PFEY; InterPro:IPR015661,IPR008271,IPR013212,IPR012572, IPR000719,IPR011009; PFAM:PF08171,PF00069,PF08311; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA]; go_process: GO:0007094 - mitotic spindle assembly checkpoint [Evidence IEA] AKAW2_80170S BUSCO:EOG09262XMN; COG:L; EggNog:ENOG410PGU1; InterPro:IPR013022,IPR018246,IPR001719,IPR036237; PFAM:PF01261; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006281 - DNA repair [Evidence IEA] AKAW2_80171A BUSCO:EOG09262R8O; COG:G; EggNog:ENOG410PFWX; InterPro:IPR004853; PFAM:PF03151; TransMembrane:10 (i132-152o164-189i222-242o248-272i279-298o304-329i341- 359o371-396i408-430o436-455i) AKAW2_80172A COG:S; EggNog:ENOG410PQ8Q; InterPro:IPR039683,IPR019181; PFAM:PF09793 AKAW2_80173A BUSCO:EOG09261W3X; COG:G; EggNog:ENOG410PF9G; InterPro:IPR006183,IPR006184,IPR036291,IPR006114, IPR006115,IPR008927,IPR013328,IPR006113; PFAM:PF03446,PF00393; go_function: GO:0004616 - phosphogluconate dehydrogenase (decarboxylating) activity [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0050661 - NADP binding [Evidence IEA]; go_process: GO:0006098 - pentose-phosphate shunt [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_80175S COG:S; EggNog:ENOG410PGNI; InterPro:IPR000504,IPR012677,IPR034215,IPR035979; PFAM:PF00076; go_function: GO:0003676 - nucleic acid binding [Evidence IEA] AKAW2_80176S COG:S; EggNog:ENOG410PUMZ; InterPro:IPR011009,IPR002575; PFAM:PF01636 AKAW2_80180A TransMembrane:1 (o6-26i) AKAW2_80181A COG:S; EggNog:ENOG410PSF9; InterPro:IPR011008,IPR009799; PFAM:PF07110; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA] AKAW2_80182S CAZy:GT25; COG:S; EggNog:ENOG410Q1SN; InterPro:IPR002654; TransMembrane:1 (i12-30o) AKAW2_80183S COG:S; EggNog:ENOG410PYZ0; InterPro:IPR036047; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_80184S COG:Q; EggNog:ENOG410PFN7; InterPro:IPR034001,IPR043926,IPR027417,IPR003593, IPR010929,IPR017871,IPR029481,IPR003439,IPR013525, IPR034003; PFAM:PF01061,PF00005,PF06422,PF14510; TransMembrane:13 (o511-529i541-562o582-605i617-635o647-667i756-774o1187- 1204i1216-1232o1252-1284i1296-1318o1324-1344i1356- 1378o1449-1469i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA]; go_function: GO:0042626 - ATPase-coupled transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_80185A COG:S; EggNog:ENOG410PPDJ AKAW2_80186A BUSCO:EOG09265E6R; COG:U; EggNog:ENOG410PJTI; PFAM:PF02466; TransMembrane:2 (i87-106o112-130i) AKAW2_80187A COG:S; EggNog:ENOG410QE3U; InterPro:IPR036864,IPR001138; PFAM:PF00172; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_80189S COG:E; EggNog:ENOG410PVT6; InterPro:IPR036249,IPR040079,IPR005955,IPR036282, IPR010987,IPR034330,IPR034333,IPR004045,IPR004046; PFAM:PF13409,PF00043,PF14497,PF13417,PF02798; go_component: GO:0005737 - cytoplasm [Evidence IEA]; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0006749 - glutathione metabolic process [Evidence IEA]; go_process: GO:0009072 - aromatic amino acid family metabolic process [Evidence IEA] AKAW2_80188A COG:G; EggNog:ENOG410PIEU; InterPro:IPR015377,IPR036462,IPR036663,IPR011234, IPR005959; PFAM:PF09298,PF01557; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0004334 - fumarylacetoacetase activity [Evidence IEA]; go_process: GO:0009072 - aromatic amino acid family metabolic process [Evidence IEA] AKAW2_80190S COG:E; EggNog:ENOG410PM1W; InterPro:IPR014710,IPR011051,IPR005708; PFAM:PF04209; go_function: GO:0004411 - homogentisate 1,2-dioxygenase activity [Evidence IEA]; go_process: GO:0006559 - L-phenylalanine catabolic process [Evidence IEA]; go_process: GO:0006570 - tyrosine metabolic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_80191A COG:S; EggNog:ENOG410PQI0; InterPro:IPR038906 AKAW2_80192S COG:E; EggNog:ENOG410PJ65; InterPro:IPR037523,IPR041735,IPR041736,IPR029068, IPR004360,IPR005956; PFAM:PF00903; go_function: GO:0003868 - 4-hydroxyphenylpyruvate dioxygenase activity [Evidence IEA]; go_function: GO:0016701 - oxidoreductase activity, acting on single donors with incorporation of molecular oxygen [Evidence IEA]; go_process: GO:0009072 - aromatic amino acid family metabolic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_80193A COG:O; EggNog:ENOG410PIT1; InterPro:IPR008913,IPR037274; PFAM:PF05495; go_function: GO:0008270 - zinc ion binding [Evidence IEA] AKAW2_80194S COG:Q; EggNog:ENOG410PFY8; InterPro:IPR001128,IPR002403,IPR017972,IPR036396; PFAM:PF00067; go_function: GO:0004497 - monooxygenase activity [Evidence IEA]; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_80195S COG:S; EggNog:ENOG410PX94; InterPro:IPR011009,IPR002575; PFAM:PF01636 AKAW2_80196A COG:S; EggNog:ENOG410PI77; InterPro:IPR021711,IPR013860; PFAM:PF08550,PF11702 AKAW2_80198A COG:C; EggNog:ENOG410PFDH; InterPro:IPR036188,IPR002938; PFAM:PF01494,PF13450; TransMembrane:1 (i12-30o); go_function: GO:0071949 - FAD binding [Evidence IEA] AKAW2_80199A BUSCO:EOG09261HM3; COG:O; EggNog:ENOG410PGD1; InterPro:IPR002423,IPR027410,IPR027413,IPR017998, IPR002194,IPR027409; PFAM:PF00118; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0051082 - unfolded protein binding [Evidence IEA]; go_process: GO:0006457 - protein folding [Evidence IEA] AKAW2_80200S COG:B; EggNog:ENOG410PQJY; InterPro:IPR000953,IPR016197,IPR023780,IPR023779, IPR008251,IPR017984; PFAM:PF01393,PF00385; go_component: GO:0005634 - nucleus [Evidence IEA] AKAW2_80201A COG:K; EggNog:ENOG410PPT7; InterPro:IPR039595,IPR009057,IPR038104,IPR021661, IPR015010; PFAM:PF11626,PF08914; go_process: GO:0000723 - telomere maintenance [Evidence IEA] AKAW2_80202S COG:S; EggNog:ENOG410PGRW; InterPro:IPR001594; PFAM:PF01529; TransMembrane:7 (o6-24i36-57o77-97i109-126o197-222i243-267o273-291i); go_function: GO:0016409 - palmitoyltransferase activity [Evidence IEA] AKAW2_80203S COG:S; EggNog:ENOG410PFKI; InterPro:IPR016024,IPR011989,IPR019156; PFAM:PF09759 AKAW2_80204A COG:O; EggNog:ENOG410PPI7; InterPro:IPR001841,IPR013083; PFAM:PF12861,PF13639 AKAW2_80205S COG:S; EggNog:ENOG410PVPP; TransMembrane:2 (o29-50i120-139o) AKAW2_80206A COG:S; EggNog:ENOG410PRDN; TransMembrane:1 (o146-166i) AKAW2_80207S COG:S; EggNog:ENOG410PXSI; TransMembrane:4 (i20-39o51-69i90-110o130-155i) AKAW2_80208A COG:M; EggNog:ENOG410PIF7; InterPro:IPR029044,IPR005835,IPR018357,IPR011004, IPR001451; PFAM:PF00483,PF12804,PF00132; go_function: GO:0016740 - transferase activity [Evidence IEA]; go_function: GO:0016779 - nucleotidyltransferase activity [Evidence IEA]; go_process: GO:0009058 - biosynthetic process [Evidence IEA] AKAW2_80209S COG:U; EggNog:ENOG410PJW1; InterPro:IPR030381,IPR027417,IPR003130,IPR001401, IPR000375,IPR022812,IPR020850; PFAM:PF00350,PF01031; go_function: GO:0003924 - GTPase activity [Evidence IEA]; go_function: GO:0005525 - GTP binding [Evidence IEA] AKAW2_80210S COG:J; EggNog:ENOG410PFUC; InterPro:IPR006195,IPR018149,IPR034762,IPR044136, IPR004365,IPR004364,IPR012340,IPR002313; PFAM:PF01336,PF00152; go_component: GO:0005737 - cytoplasm [Evidence IEA]; go_function: GO:0000166 - nucleotide binding [Evidence IEA]; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0004812 - aminoacyl-tRNA ligase activity [Evidence IEA]; go_function: GO:0004824 - lysine-tRNA ligase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006418 - tRNA aminoacylation for protein translation [Evidence IEA]; go_process: GO:0006430 - lysyl-tRNA aminoacylation [Evidence IEA] AKAW2_80212A COG:O; EggNog:ENOG410PFR2; InterPro:IPR003780,IPR023754; PFAM:PF02628; TransMembrane:8 (i108-128o213-231i243-261o281-302i336-362o409-427i448- 467o473-494i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0016627 - oxidoreductase activity, acting on the CH-CH group of donors [Evidence IEA]; go_process: GO:0006784 - heme A biosynthetic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_80213S CAZy:GH106; COG:S; EggNog:ENOG410PVEI; InterPro:IPR008979; PFAM:PF17132; SECRETED:SignalP(1-19); antiSMASH:Cluster_8.2 AKAW2_80214A COG:V; EggNog:ENOG410PGQ5; InterPro:IPR036291,IPR001509; PFAM:PF04321,PF13460,PF01370; SMCOG1010:NAD-dependent epimerase/dehydratase; antiSMASH:Cluster_8.2; go_function: GO:0003824 - catalytic activity [Evidence IEA] AKAW2_80215A COG:Q; EggNog:ENOG410PNXT; InterPro:IPR002347,IPR036291,IPR020904; PFAM:PF00106,PF13561,PF08659; SMCOG1001:short-chain dehydrogenase/reductase SDR; antiSMASH:Cluster_8.2; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_80216A antiSMASH:Cluster_8.2 AKAW2_80217S COG:S; EggNog:ENOG410PIN3; InterPro:IPR013909,IPR012935; PFAM:PF08600,PF07967; antiSMASH:Cluster_8.2; go_function: GO:0008270 - zinc ion binding [Evidence IEA] AKAW2_80218A COG:C; EggNog:ENOG410Q18X; InterPro:IPR036188,IPR002938; PFAM:PF01494; SMCOG1087:hypothetical protein; TransMembrane:1 (i445-464o); antiSMASH:Cluster_8.2; go_function: GO:0071949 - FAD binding [Evidence IEA] AKAW2_80219A COG:S; EggNog:ENOG410Q0C1; InterPro:IPR039020; TransMembrane:7 (o18-36i48-71o77-95i115-134o140-160i172-193o205-227i); antiSMASH:Cluster_8.2 AKAW2_80220S COG:H; EggNog:ENOG410PXDT; InterPro:IPR008949,IPR000092; PFAM:PF00348; SMCOG1182:Polyprenyl synthetase; TransMembrane:1 (o12-29i); antiSMASH:Cluster_8.2; go_process: GO:0008299 - isoprenoid biosynthetic process [Evidence IEA] AKAW2_80221S COG:Q; EggNog:ENOG410PHH6; InterPro:IPR001128,IPR002401,IPR036396; PFAM:PF00067; SMCOG1034:cytochrome P450; TransMembrane:5 (o6-27i34-57o63-86i264-282o341-362i); antiSMASH:Cluster_8.2; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_80222S BUSCO:EOG09262QTY; COG:A; EggNog:ENOG410PHZU; InterPro:IPR039753,IPR029063,IPR004971; PFAM:PF03291; antiSMASH:Cluster_8.2; go_function: GO:0004482 - mRNA (guanine-N7-)-methyltransferase activity [Evidence IEA] AKAW2_80223S COG:L; EggNog:ENOG410PQBA; InterPro:IPR026846,IPR004181,IPR013083; PFAM:PF11789; antiSMASH:Cluster_8.2; go_component: GO:0030915 - Smc5-Smc6 complex [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_function: GO:0019789 - SUMO transferase activity [Evidence IEA]; go_process: GO:0000724 - double-strand break repair via homologous recombination [Evidence IEA] AKAW2_80224A COG:C; EggNog:ENOG410PWAU; InterPro:IPR018108,IPR023395,IPR002067; PFAM:PF00153; TransMembrane:1 (o239-259i); antiSMASH:Cluster_8.2; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_80226A COG:C; EggNog:ENOG410PI78; InterPro:IPR008210,IPR013035,IPR015994,IPR001272; PFAM:PF01293; go_function: GO:0004611 - phosphoenolpyruvate carboxykinase activity [Evidence IEA]; go_function: GO:0004612 - phosphoenolpyruvate carboxykinase (ATP) activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0017076 - purine nucleotide binding [Evidence IEA]; go_process: GO:0006094 - gluconeogenesis [Evidence IEA] AKAW2_80228A BUSCO:EOG0926436T; COG:U; EggNog:ENOG410PJZK; InterPro:IPR008733; PFAM:PF05648; TransMembrane:1 (o141-159i); go_component: GO:0005779 - integral component of peroxisomal membrane [Evidence IEA]; go_process: GO:0016559 - peroxisome fission [Evidence IEA] AKAW2_80229A TransMembrane:1 (o38-58i) AKAW2_80230A COG:P; EggNog:ENOG410PGCE; InterPro:IPR020846,IPR005828,IPR036259; PFAM:PF07690; TransMembrane:11 (o84-103i110-132o138-160i181-208o214-233i253-274o303- 321i333-354o360-377i398-420o435-453i); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_80231S BUSCO:EOG09260Y2Q; COG:O; EggNog:ENOG410PFGD; InterPro:IPR019585,IPR036390,IPR035268,IPR000717; PFAM:PF10602,PF01399; go_function: GO:0030234 - enzyme regulator activity [Evidence IEA] AKAW2_80232S COG:E; EggNog:ENOG410PGK7; InterPro:IPR004839,IPR015424,IPR015421,IPR015422; PFAM:PF00155; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0030170 - pyridoxal phosphate binding [Evidence IEA]; go_process: GO:0009058 - biosynthetic process [Evidence IEA] AKAW2_80233S COG:L; EggNog:ENOG410QE6J; InterPro:IPR009060,IPR002625,IPR003892,IPR013899, IPR036063; PFAM:PF02845,PF08590; go_function: GO:0005515 - protein binding [Evidence IEA]; go_function: GO:0043130 - ubiquitin binding [Evidence IEA] AKAW2_80234S BUSCO:EOG09264NEF; COG:O; EggNog:ENOG410PPVG; InterPro:IPR011057,IPR028427,IPR002579; PFAM:PF01641; go_function: GO:0016671 - oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor [Evidence IEA]; go_function: GO:0033743 - peptide-methionine (R)-S-oxide reductase activity [Evidence IEA]; go_process: GO:0006979 - response to oxidative stress [Evidence IEA]; go_process: GO:0030091 - protein repair [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_80235S COG:T; EggNog:ENOG410PHZ5; InterPro:IPR001164,IPR037278,IPR038508; PFAM:PF01412; go_function: GO:0005096 - GTPase activator activity [Evidence IEA] AKAW2_80236S COG:S; EggNog:ENOG410QDK3; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_80237A BUSCO:EOG09260WUA; COG:S; EggNog:ENOG410PM7M; InterPro:IPR003150; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_80238S COG:S; EggNog:ENOG410PY05; antiSMASH:Cluster_8.4 AKAW2_80239S COG:S; EggNog:ENOG410PUYD; InterPro:IPR021858; PFAM:PF11951; antiSMASH:Cluster_8.4 AKAW2_80240S TransMembrane:1 (o6-22i); antiSMASH:Cluster_8.4 AKAW2_80241A COG:E; EggNog:ENOG410PWK8; InterPro:IPR002293; PFAM:PF00324,PF13520; SMCOG1038:phenylalanine-specific permease; TransMembrane:11 (o29-51i63-87o121-143i155-176o182-203i263-286o316-336i367- 385o391-415i435-456o462-485i); antiSMASH:Cluster_8.4; go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_80242A antiSMASH:Cluster_8.4 AKAW2_80243A COG:C; EggNog:ENOG410PJHR; InterPro:IPR006094,IPR036318,IPR016166,IPR016167, IPR016169; PFAM:PF01565; SMCOG1138:FAD linked oxidase domain protein; antiSMASH:Cluster_8.4; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_function: GO:0071949 - FAD binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_80244A COG:Q; EggNog:ENOG410PG90; InterPro:IPR013154,IPR013149,IPR002328,IPR036291, IPR011032,IPR020843; PFAM:PF00107,PF08240; SMCOG1040:alcohol dehydrogenase; antiSMASH:Cluster_8.4; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_80245S COG:I; EggNog:ENOG410PJ6Y; InterPro:IPR016035,IPR016039,IPR014030,IPR014031, IPR001227,IPR032821,IPR010071,IPR014043,IPR020806, IPR020845,IPR020841,IPR000873,IPR009081,IPR036736, IPR042099,IPR025110; PFAM:PF16197,PF00550,PF02801,PF00501,PF13193, PF00109; SMCOG1002:AMP-dependent synthetase and ligase; antiSMASH:Cluster_8.4; go_function: GO:0016740 - transferase activity [Evidence IEA]; go_function: GO:0016746 - transferase activity, transferring acyl groups [Evidence IEA]; go_function: GO:0031177 - phosphopantetheine binding [Evidence IEA] AKAW2_80246S COG:I; EggNog:ENOG410PJ6Y; InterPro:IPR016035,IPR001227,IPR014043,IPR036291, IPR013968; PFAM:PF00106,PF00698,PF08659; antiSMASH:Cluster_8.4; go_function: GO:0016740 - transferase activity [Evidence IEA] AKAW2_80247S COG:I; EggNog:ENOG410PJ6Y; InterPro:IPR009081,IPR006162,IPR036291,IPR036736, IPR010080,IPR020806,IPR013120,IPR013968; PFAM:PF00550,PF07993,PF01370; antiSMASH:Cluster_8.4; go_function: GO:0031177 - phosphopantetheine binding [Evidence IEA] AKAW2_80248A COG:G; EggNog:ENOG410PFSN; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; SMCOG1005:Drug resistance transporter, EmrB/QacA; TransMembrane:12 (i108-130o145-166i173-191o203-224i236-257o263-283i329- 355o375-399i419-439o445-467i479-505o511-533i); antiSMASH:Cluster_8.4; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_80249A antiSMASH:Cluster_8.4 AKAW2_80250A COG:K; EggNog:ENOG410PNTX; InterPro:IPR036864,IPR001138; PFAM:PF00172; antiSMASH:Cluster_8.4; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_80251S antiSMASH:Cluster_8.4 AKAW2_80252S COG:L; EggNog:ENOG410PMII; InterPro:IPR036395,IPR001083; PFAM:PF00649; antiSMASH:Cluster_8.4; go_component: GO:0005634 - nucleus [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0003700 - DNA-binding transcription factor activity [Evidence IEA]; go_function: GO:0005507 - copper ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_80253A SECRETED:SignalP(1-18) AKAW2_80254S COG:S; EggNog:ENOG410PT9V; InterPro:IPR018466; PFAM:PF10342; SECRETED:SignalP(1-19) AKAW2_80255A COG:K; EggNog:ENOG410PIS0; InterPro:IPR015943,IPR001680,IPR036322,IPR017986; PFAM:PF00400; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_80256A BUSCO:EOG0926133I; COG:V; EggNog:ENOG410PH4W; InterPro:IPR020860,IPR011992,IPR001806,IPR018247, IPR027417,IPR021181,IPR002048,IPR013567,IPR013566; PFAM:PF00071,PF08355,PF08356,PF08477; TransMembrane:1 (o604-625i); go_component: GO:0031307 - integral component of mitochondrial outer membrane [Evidence IEA]; go_function: GO:0003924 - GTPase activity [Evidence IEA]; go_function: GO:0005509 - calcium ion binding [Evidence IEA]; go_function: GO:0005525 - GTP binding [Evidence IEA]; go_process: GO:0007005 - mitochondrion organization [Evidence IEA] AKAW2_80257S COG:S; EggNog:ENOG410PFWF; InterPro:IPR033643,IPR036028,IPR007461,IPR001452; PFAM:PF00018,PF04366,PF14604,PF07653; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_80258S COG:S; EggNog:ENOG410PH6C; InterPro:IPR013941,IPR040206; PFAM:PF08632 AKAW2_80259S COG:U; EggNog:ENOG410PQWD; InterPro:IPR039899,IPR039897; TransMembrane:1 (i74-96o); go_component: GO:0030173 - integral component of Golgi membrane [Evidence IEA]; go_process: GO:0015031 - protein transport [Evidence IEA] AKAW2_80261S COG:S; EggNog:ENOG410PGXT; InterPro:IPR014756,IPR014752,IPR011021,IPR011022; PFAM:PF00339,PF02752 AKAW2_80262S COG:T; EggNog:ENOG410PI3A; InterPro:IPR043453,IPR001849,IPR027267,IPR011993 AKAW2_80263A COG:S; EggNog:ENOG410PV2G AKAW2_80264S COG:G; EggNog:ENOG410PHWD; InterPro:IPR037523,IPR029068,IPR018146,IPR004361, IPR004360; PFAM:PF13669,PF00903; go_function: GO:0004462 - lactoylglutathione lyase activity [Evidence IEA]; go_function: GO:0046872 - metal ion binding [Evidence IEA] AKAW2_80265S COG:K; EggNog:ENOG410PVHN; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; TransMembrane:1 (i689-706o); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_80266S COG:S; EggNog:ENOG410PNCM; InterPro:IPR029058,IPR013094; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_80268A COG:S; EggNog:ENOG410Q1NW AKAW2_80269S COG:S; EggNog:ENOG410Q2Z1 AKAW2_80270A COG:O,T; EggNog:ENOG410PG3B; InterPro:IPR038765,IPR001300; MEROPS:MER0016159; go_function: GO:0004198 - calcium-dependent cysteine-type endopeptidase activity [Evidence IEA]; go_process: GO:0006508 - proteolysis [Evidence IEA] AKAW2_80271A COG:O,T; EggNog:ENOG410PG3B; InterPro:IPR038765,IPR001300,IPR022684; MEROPS:MER0019360; go_function: GO:0004198 - calcium-dependent cysteine-type endopeptidase activity [Evidence IEA]; go_process: GO:0006508 - proteolysis [Evidence IEA] AKAW2_80273A InterPro:IPR024079; SECRETED:SignalP(1-18); go_function: GO:0008237 - metallopeptidase activity [Evidence IEA] AKAW2_80274S CAZy:GH18; COG:G; EggNog:ENOG410PI86; InterPro:IPR036861,IPR011583,IPR029070,IPR001223, IPR017853,IPR018371,IPR018392,IPR001002,IPR001579, IPR036779; PFAM:PF00187,PF00704,PF01476; SECRETED:SignalP(1-21); go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_function: GO:0008061 - chitin binding [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_80275A COG:D; EggNog:ENOG410PFG7; InterPro:IPR017441,IPR008271,IPR000719,IPR011009; PFAM:PF07714,PF00069; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_80276S COG:A; EggNog:ENOG410PN0E; InterPro:IPR027450,IPR004574,IPR037151,IPR005123; PFAM:PF13532; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_80278S COG:I,J,T; EggNog:ENOG410PFMP; InterPro:IPR023631,IPR036928,IPR020556; PFAM:PF01425 AKAW2_80279A COG:Q; EggNog:ENOG410PHET; InterPro:IPR001128,IPR002401,IPR036396; PFAM:PF00067; TransMembrane:1 (i26-48o); go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_80280A COG:E; EggNog:ENOG410PIN5; InterPro:IPR001261,IPR036322,IPR017149,IPR002933, IPR015943,IPR011650,IPR001680,IPR017986; MEROPS:MER0026494; PFAM:PF01546,PF07687; go_function: GO:0005515 - protein binding [Evidence IEA]; go_function: GO:0016787 - hydrolase activity [Evidence IEA]; go_process: GO:0006751 - glutathione catabolic process [Evidence IEA] AKAW2_80281S COG:S; EggNog:ENOG410PN3X; TransMembrane:1 (o245-269i) AKAW2_80283S COG:I; EggNog:ENOG410PVXN; InterPro:IPR036188,IPR002938; PFAM:PF01494; go_function: GO:0071949 - FAD binding [Evidence IEA] AKAW2_80284A BUSCO:EOG09263H0Y; COG:S; EggNog:ENOG410PGSI; InterPro:IPR008010; PFAM:PF05346; TransMembrane:3 (o413-434i611-634o918-948i) AKAW2_80285A COG:C; EggNog:ENOG410QE0F; InterPro:IPR036188,IPR002938; PFAM:PF01494; go_function: GO:0071949 - FAD binding [Evidence IEA] AKAW2_80286A COG:S; EggNog:ENOG410PY0R; SECRETED:SignalP(1-17); TransMembrane:1 (n2-12c17/18o184-206i) AKAW2_80287S COG:S; EggNog:ENOG410Q1T7; TransMembrane:5 (o28-47i59-82o102-124i136-158o215-233i) AKAW2_80288A COG:D; EggNog:ENOG410PGBA; InterPro:IPR017441,IPR008271,IPR000719,IPR011009; PFAM:PF07714,PF00069; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_80289S COG:C; EggNog:ENOG410PID1; InterPro:IPR001670,IPR039697; PFAM:PF00465; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0046872 - metal ion binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_80290S CAZy:GH43; COG:G; EggNog:ENOG410PN7Q; InterPro:IPR023296,IPR006710; PFAM:PF04616; SECRETED:SignalP(1-23); go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_80292A COG:S; EggNog:ENOG410PGRM AKAW2_80293A COG:G; EggNog:ENOG410Q18F; InterPro:IPR013078,IPR029033; PFAM:PF00300 AKAW2_80294A COG:O; EggNog:ENOG410PIM3; InterPro:IPR000569,IPR035983,IPR032353; PFAM:PF00632,PF16558; go_function: GO:0004842 - ubiquitin-protein transferase activity [Evidence IEA] AKAW2_80295A COG:Q; EggNog:ENOG410PU8B; InterPro:IPR013154,IPR013149,IPR002328,IPR036291, IPR011032,IPR020843; PFAM:PF00107,PF08240; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_80296A COG:S; EggNog:ENOG410PWBT AKAW2_80297A COG:S; EggNog:ENOG410PWBT; InterPro:IPR001138,IPR007219,IPR036864; PFAM:PF04082; TransMembrane:4 (o254-271i292-309o321-338i358-379o); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_80298S COG:Q; EggNog:ENOG410PIER; InterPro:IPR001128,IPR002403,IPR017972,IPR036396; PFAM:PF00067; go_function: GO:0004497 - monooxygenase activity [Evidence IEA]; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_80299A COG:Q; EggNog:ENOG410PKA8; InterPro:IPR002347,IPR036291,IPR020904; PFAM:PF00106,PF13561,PF08659; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_80300S COG:Q; EggNog:ENOG410PUMM; InterPro:IPR002347,IPR036291,IPR020904; PFAM:PF00106,PF13561,PF08659; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_80301S COG:S; EggNog:ENOG410PKUG; InterPro:IPR036236,IPR041661,IPR022755,IPR003604, IPR013087,IPR040025; PFAM:PF12171,PF12874; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA] AKAW2_80302A COG:P; EggNog:ENOG410PH9S; InterPro:IPR002550,IPR000644; PFAM:PF01595; SECRETED:SignalP(1-35); TransMembrane:4 (n15-27c35/36o55-79i115-135o141-160i172-192o) AKAW2_80303S COG:S; EggNog:ENOG410Q22Z; TransMembrane:4 (i29-49o61-84i105-123o206-227i) AKAW2_80304S TransMembrane:1 (i65-89o) AKAW2_80305S COG:S; EggNog:ENOG410PJ21; InterPro:IPR031606; PFAM:PF16944; TransMembrane:3 (i37-59o79-100i224-257o); go_component: GO:0005887 - integral component of plasma membrane [Evidence IEA]; go_function: GO:0015079 - potassium ion transmembrane transporter activity [Evidence IEA]; go_process: GO:0071805 - potassium ion transmembrane transport [Evidence IEA] AKAW2_80306A CAZy:CBM20; CAZy:GH13; COG:G; EggNog:ENOG410PGMM; InterPro:IPR034836,IPR006047,IPR017853,IPR015340, IPR013783,IPR013780,IPR013784,IPR002044; PFAM:PF00686,PF00128,PF09260; SECRETED:SignalP(1-24); go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0004556 - alpha-amylase activity [Evidence IEA]; go_function: GO:0005509 - calcium ion binding [Evidence IEA]; go_function: GO:0030246 - carbohydrate binding [Evidence IEA]; go_function: GO:2001070 - starch binding [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA]; go_process: GO:0016052 - carbohydrate catabolic process [Evidence IEA] AKAW2_80307A COG:G; EggNog:ENOG410PGZK; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i145-164o170-191i203-225o231-255i267-286o292-321i341- 362o368-391i403-421o433-457i469-492o540-559i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_80308S BUSCO:EOG092638EN; COG:I; EggNog:ENOG410PREB; InterPro:IPR022742,IPR029058; MEROPS:MER0036114; PFAM:PF12697,PF12146 AKAW2_80309S COG:S; EggNog:ENOG410PFWF; InterPro:IPR007461,IPR033643; PFAM:PF04366 AKAW2_80310S COG:S; EggNog:ENOG410PX3W; InterPro:IPR036047,IPR032675; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_80311S COG:L; EggNog:ENOG410PQ68; InterPro:IPR036397,IPR013520,IPR012337; PFAM:PF00929; go_function: GO:0003676 - nucleic acid binding [Evidence IEA] AKAW2_80312S SECRETED:SignalP(1-20) AKAW2_80313S COG:Q; EggNog:ENOG410PG34; InterPro:IPR001128,IPR017972,IPR002401,IPR036396; PFAM:PF00067; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_80314S COG:S; EggNog:ENOG410PYBV; SECRETED:SignalP(1-16) AKAW2_80315A COG:A; EggNog:ENOG410PKD8; InterPro:IPR011047,IPR036322,IPR015943,IPR001680, IPR019775,IPR020472,IPR017986; PFAM:PF00400; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_80316A COG:A; EggNog:ENOG410PKD8; InterPro:IPR027417,IPR031359,IPR007111; PFAM:PF17100 AKAW2_80317A COG:Q; EggNog:ENOG410PHH6; InterPro:IPR001128,IPR002403,IPR036396; PFAM:PF00067; TransMembrane:4 (o15-31i43-62o68-96i360-381o); go_function: GO:0004497 - monooxygenase activity [Evidence IEA]; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_80318A COG:S; EggNog:ENOG410PKP8; TransMembrane:6 (o23-45i57-78o98-121i133-154o174-200i212-229o) AKAW2_80320S COG:Q; EggNog:ENOG410PHJE; InterPro:IPR001128,IPR017972,IPR002401,IPR036396; PFAM:PF00067; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_80319A COG:S; EggNog:ENOG410PSN3; InterPro:IPR023213 AKAW2_80321S COG:Q; EggNog:ENOG410PPHD; InterPro:IPR002347,IPR036291; PFAM:PF00106,PF13561,PF08659,PF01370; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_80322A COG:Q; EggNog:ENOG410PK67; InterPro:IPR020946,IPR036188; PFAM:PF07992,PF13450; go_function: GO:0004499 - N,N-dimethylaniline monooxygenase activity [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_function: GO:0050661 - NADP binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_80323S COG:Q; EggNog:ENOG410PKH2; InterPro:IPR001128,IPR002403,IPR017972,IPR036396; PFAM:PF00067; go_function: GO:0004497 - monooxygenase activity [Evidence IEA]; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_80324S COG:S; EggNog:ENOG410PXII; InterPro:IPR008949; PFAM:PF19086 AKAW2_80325S COG:C; EggNog:ENOG410PI5D; InterPro:IPR012133,IPR037458,IPR037396,IPR013785, IPR000262; PFAM:PF01070; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0010181 - FMN binding [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_80326A COG:S; EggNog:ENOG410PICM AKAW2_80327A COG:S; EggNog:ENOG410PZ49; SECRETED:SignalP(1-16) AKAW2_80328A COG:G; EggNog:ENOG410PK1X; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i49-66o92-112i119-138o144-167i179-201o213-235i285- 305o317-339i351-369o375-397i409-430o436-458i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_80329A COG:Q; EggNog:ENOG410PW54; InterPro:IPR001128,IPR017972,IPR002401,IPR036396; PFAM:PF00067; TransMembrane:1 (o6-26i); go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_80330S COG:Q; EggNog:ENOG410PG1V; InterPro:IPR036396; TransMembrane:1 (o31-49i); go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_80331S COG:Q; EggNog:ENOG410PG1V; InterPro:IPR001128,IPR017972,IPR002401,IPR036396; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_80332A CAZy:AA1; COG:Q; EggNog:ENOG410PGU0; InterPro:IPR008972,IPR011707,IPR011706,IPR001117; PFAM:PF00394,PF07732,PF07731; SECRETED:SignalP(1-19); go_function: GO:0005507 - copper ion binding [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_80333S COG:O; EggNog:ENOG410PU84; InterPro:IPR011118,IPR029058; PFAM:PF07519; SECRETED:SignalP(1-19) AKAW2_80334S CAZy:CBM50; COG:S; EggNog:ENOG410PSHX; InterPro:IPR018392,IPR036779; PFAM:PF01476; SECRETED:SignalP(1-21) AKAW2_80335A COG:S; EggNog:ENOG410Q2XW; InterPro:IPR007568; PFAM:PF04479; TransMembrane:7 (o23-42i49-69o89-112i124-147o167-189i201-218o238-259i); go_component: GO:0016021 - integral component of membrane [Evidence IEA] AKAW2_80336S COG:I; EggNog:ENOG410PMD3; InterPro:IPR042098,IPR003819; PFAM:PF02668; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_80337S COG:S; EggNog:ENOG410PVQW; InterPro:IPR036864,IPR007219,IPR001138; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_80338S COG:T; EggNog:ENOG410PFPV; InterPro:IPR004813; TransMembrane:2 (i117-136o142-161i); go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_80339S COG:T; EggNog:ENOG410PFPV; InterPro:IPR004813,IPR004648; PFAM:PF03169; TransMembrane:12 (o37-58i102-120o140-167i174-197o248-271i310-330o336- 359i420-443o490-508i515-531o537-553i565-587o); go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_80340A COG:S; EggNog:ENOG410PWMP; TransMembrane:7 (o31-47i52-72o122-140i152-172o274-292i367-395o415-433i) AKAW2_80341S COG:S; EggNog:ENOG410PJSE; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_80342S COG:Q; EggNog:ENOG410PFU6; InterPro:IPR036291,IPR002347; PFAM:PF00106,PF13561; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_80343A COG:Q; EggNog:ENOG410PFT4; InterPro:IPR036291,IPR002347; PFAM:PF08659,PF00106,PF13561; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_80344A COG:Q; EggNog:ENOG410PVPB; InterPro:IPR013154,IPR013149,IPR002328,IPR036291, IPR011032,IPR020843; PFAM:PF00107,PF08240; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_80345S COG:S; EggNog:ENOG410PVIM; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_80346A COG:G; EggNog:ENOG410PFRN; InterPro:IPR005829,IPR005828,IPR003663,IPR036259, IPR020846; PFAM:PF00083,PF07690; TransMembrane:12 (i12-38o58-77i84-102o108-132i144-165o177-198i263-287o302- 323i330-352o364-383i404-423o435-454i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_80348A COG:S; EggNog:ENOG410Q2HD; TransMembrane:7 (o16-34i46-66o86-112i124-146o180-198i205-223o254-273i) AKAW2_80349S COG:C; EggNog:ENOG410PIAC; InterPro:IPR006094,IPR036318,IPR016166,IPR012951; PFAM:PF08031,PF01565; SECRETED:SignalP(1-20); go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_function: GO:0071949 - FAD binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_80350S COG:S; EggNog:ENOG410PWZ2; InterPro:IPR039535; PFAM:PF05935,PF14269; SECRETED:SignalP(1-20) AKAW2_80351S COG:O; EggNog:ENOG410PXV4; InterPro:IPR006771; PFAM:PF04681; SECRETED:SignalP(1-16) AKAW2_80352S COG:S; EggNog:ENOG410PJ23; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172; TransMembrane:1 (o498-516i); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_80353A COG:S; EggNog:ENOG410PJVK; InterPro:IPR008775; PFAM:PF05721 AKAW2_80354S COG:C,H; EggNog:ENOG410PJY7; InterPro:IPR036188,IPR002938; PFAM:PF01494; go_function: GO:0071949 - FAD binding [Evidence IEA] AKAW2_80355S COG:S; EggNog:ENOG410PPVM; InterPro:IPR014710,IPR011051,IPR013096; PFAM:PF07883 AKAW2_80356S COG:S; EggNog:ENOG410PHJP; InterPro:IPR012349,IPR002563; PFAM:PF01613; go_function: GO:0010181 - FMN binding [Evidence IEA] AKAW2_80357S COG:S; EggNog:ENOG410PSN8; InterPro:IPR011008,IPR005545; PFAM:PF03795 AKAW2_80358A COG:O; EggNog:ENOG410PGD9; InterPro:IPR027417,IPR003593,IPR003959; PFAM:PF00004; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA] AKAW2_80359S COG:S; EggNog:ENOG410PK7N; InterPro:IPR027417,IPR007111; PFAM:PF05729 AKAW2_80360S COG:T; EggNog:ENOG410QARK; InterPro:IPR015915; PFAM:PF13418,PF01344,PF13415,PF13964; SECRETED:SignalP(1-21); go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_80361S COG:T; EggNog:ENOG410QARK; InterPro:IPR015915; PFAM:PF13415; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_80362S COG:E; EggNog:ENOG410PK06; InterPro:IPR002220,IPR013785; PFAM:PF00701; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0016829 - lyase activity [Evidence IEA] AKAW2_80363S COG:S; EggNog:ENOG410PJF3; InterPro:IPR007219; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA] AKAW2_80364S COG:S; EggNog:ENOG410PJF3; TransMembrane:1 (i146-164o) AKAW2_80365S COG:G; EggNog:ENOG410PHCB; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (o42-59i71-94o114-132i139-161o173-194i206-228o276-295i315- 334o340-359i371-388o408-427i439-463o); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_80366A COG:S; EggNog:ENOG410PT45 AKAW2_80367S COG:I; EggNog:ENOG410Q24M; InterPro:IPR001753,IPR029045; PFAM:PF16113,PF00378; go_function: GO:0003824 - catalytic activity [Evidence IEA] AKAW2_80368S COG:K; EggNog:ENOG410PV8C; InterPro:IPR007219; PFAM:PF04082; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA] AKAW2_80369S COG:K; EggNog:ENOG410QEEY AKAW2_80370S COG:S; EggNog:ENOG410PFYR AKAW2_80371S COG:S; EggNog:ENOG410PV4E AKAW2_80372A COG:G,M; EggNog:ENOG410PKT0; InterPro:IPR036291,IPR016040; PFAM:PF13460,PF05368 AKAW2_80373S COG:C; EggNog:ENOG410PHJW; InterPro:IPR044152,IPR001155,IPR013785; PFAM:PF00724; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0003959 - NADPH dehydrogenase activity [Evidence IEA]; go_function: GO:0010181 - FMN binding [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0050661 - NADP binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_80374S COG:L; EggNog:ENOG410PFT5; InterPro:IPR003959,IPR027417,IPR003593,IPR021886, IPR008921,IPR032423; PFAM:PF16193,PF00004,PF05496,PF12002,PF07728; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA]; go_process: GO:0006260 - DNA replication [Evidence IEA] AKAW2_80375A COG:S; EggNog:ENOG410Q1YI; InterPro:IPR036864,IPR021858,IPR001138; PFAM:PF00172,PF11951; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_80376S CAZy:CE10; COG:S; EggNog:ENOG410PXIX; InterPro:IPR000073,IPR029058,IPR013094; MEROPS:MER0042911; PFAM:PF07859; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_80377A CAZy:PL1; COG:G; EggNog:ENOG410PIPP; InterPro:IPR012334,IPR002022,IPR011050; PFAM:PF00544; SECRETED:SignalP(1-18) AKAW2_80379A COG:S; EggNog:ENOG410PW02; InterPro:IPR021514; PFAM:PF11374; TransMembrane:2 (i82-106o126-149i) AKAW2_80380S COG:S; EggNog:ENOG410PN1X; InterPro:IPR038697,IPR015920; PFAM:PF16010; SECRETED:SignalP(1-19) AKAW2_80381S COG:S; EggNog:ENOG410PIBZ; InterPro:IPR011990,IPR019734; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_80383S COG:Q; EggNog:ENOG410PUZU; InterPro:IPR013154,IPR013149,IPR002328,IPR036291, IPR011032,IPR020843; PFAM:PF00107,PF08240,PF13602; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_80384A COG:K; EggNog:ENOG410PWBZ; InterPro:IPR036864,IPR001138; PFAM:PF00172; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_80385S COG:S; EggNog:ENOG410PXFY; InterPro:IPR005624,IPR010371,IPR038084; PFAM:PF03928 AKAW2_80386A COG:O; EggNog:ENOG410PH5U; InterPro:IPR018181,IPR029047,IPR013126,IPR042050, IPR043129; PFAM:PF00012,PF06723; SECRETED:SignalP(1-38) AKAW2_80387A COG:J; EggNog:ENOG410PF8R; InterPro:IPR015033,IPR005225,IPR027417,IPR000795, IPR031157,IPR004161,IPR004160,IPR009001,IPR009000; PFAM:PF00009,PF08938,PF01926,PF03143,PF03144; SMCOG1190:GTP-binding protein LepA; antiSMASH:Cluster_8.5; go_function: GO:0003924 - GTPase activity [Evidence IEA]; go_function: GO:0005525 - GTP binding [Evidence IEA] AKAW2_80388A COG:L; EggNog:ENOG410PIB0; InterPro:IPR012337,IPR038765,IPR036397,IPR015943, IPR013520,IPR028881,IPR028889,IPR030843,IPR036322; MEROPS:MER0030317; PFAM:PF13423,PF00929; antiSMASH:Cluster_8.5; go_component: GO:0031251 - PAN complex [Evidence IEA]; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0004535 - poly(A)-specific ribonuclease activity [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0000289 - nuclear-transcribed mRNA poly(A) tail shortening [Evidence IEA]; go_process: GO:0006397 - mRNA processing [Evidence IEA] AKAW2_80389A COG:Q; EggNog:ENOG410PGYE; InterPro:IPR001128,IPR017972,IPR002401,IPR036396; PFAM:PF00067; SMCOG1034:cytochrome P450; TransMembrane:1 (o6-25i); antiSMASH:Cluster_8.5; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_80390S COG:S; EggNog:ENOG410PY42; SECRETED:SignalP(1-22); antiSMASH:Cluster_8.5 AKAW2_80391A COG:G; EggNog:ENOG410QDTU; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; SMCOG1137:Major facilitator superfamily MFS 1; TransMembrane:12 (i32-60o72-95i102-121o127-147i159-179o191-211i232-258o270- 288i300-318o324-343i364-385o391-415i); antiSMASH:Cluster_8.5; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_80392S COG:S; EggNog:ENOG410Q1S5; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; TransMembrane:2 (i236-253o288-308i); antiSMASH:Cluster_8.5; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_80393A COG:I; EggNog:ENOG410PJU0; InterPro:IPR000873,IPR009081,IPR006162,IPR036736, IPR036291,IPR013120,IPR042099,IPR020845; PFAM:PF00501,PF00550,PF01370,PF07993; SMCOG1002:AMP-dependent synthetase and ligase; antiSMASH:Cluster_8.5 AKAW2_80394A COG:C; EggNog:ENOG410PMCP; InterPro:IPR013154,IPR013149,IPR036291,IPR011032, IPR020843; PFAM:PF00107,PF08240; SMCOG1028:crotonyl-CoA reductase / alcohol dehydrogenase; antiSMASH:Cluster_8.5; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_80395S COG:Q; EggNog:ENOG410PFKE; InterPro:IPR009081,IPR036736,IPR036291,IPR020806, IPR013968; PFAM:PF00106,PF00550,PF13561,PF08659; SMCOG1001:short-chain dehydrogenase/reductase SDR; antiSMASH:Cluster_8.5; go_function: GO:0031177 - phosphopantetheine binding [Evidence IEA] AKAW2_80396A COG:Q; EggNog:ENOG410QECW; InterPro:IPR002347,IPR036291,IPR020904; PFAM:PF00106,PF13561,PF08659; SMCOG1001:short-chain dehydrogenase/reductase SDR; antiSMASH:Cluster_8.5; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_80398S COG:S; EggNog:ENOG410PY17; antiSMASH:Cluster_8.5 AKAW2_80397A COG:U; EggNog:ENOG410PKY6; InterPro:IPR002014,IPR004152,IPR036028,IPR001452, IPR008942; PFAM:PF14604,PF03127,PF00018,PF00790,PF07653; antiSMASH:Cluster_8.5; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0006886 - intracellular protein transport [Evidence IEA] AKAW2_80399A COG:T; EggNog:ENOG410PGP3; InterPro:IPR017441,IPR000095,IPR033923,IPR000719, IPR011009,IPR036936; PFAM:PF00786; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0004674 - protein serine/threonine kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_80400A COG:P; EggNog:ENOG410Q2C5; InterPro:IPR001248,IPR026030,IPR038271; PFAM:PF02133; TransMembrane:12 (i68-89o101-125i137-156o176-197i206-223o243-266i278- 303o333-355i367-386o398-420i441-460o480-496i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_80401S COG:A; EggNog:ENOG410PJVF; InterPro:IPR004087,IPR004088,IPR036612; PFAM:PF00013; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0003723 - RNA binding [Evidence IEA] AKAW2_80402A COG:C; EggNog:ENOG410PPP8; InterPro:IPR036400,IPR018506,IPR001199; PFAM:PF00173; TransMembrane:1 (i109-129o); go_function: GO:0020037 - heme binding [Evidence IEA] AKAW2_80403A COG:O; EggNog:ENOG410PFIE; InterPro:IPR038765,IPR001763,IPR001394,IPR028889, IPR036873; MEROPS:MER0000862; PFAM:PF13423,PF00443; go_function: GO:0004843 - thiol-dependent ubiquitin-specific protease activity [Evidence IEA]; go_process: GO:0016579 - protein deubiquitination [Evidence IEA] AKAW2_80404S BUSCO:EOG09261ZXZ; COG:U; EggNog:ENOG410PG8C; InterPro:IPR002014,IPR017073,IPR017455,IPR011011, IPR000306,IPR003903,IPR013083,IPR008942; PFAM:PF02809,PF00790,PF01363; go_function: GO:0046872 - metal ion binding [Evidence IEA]; go_process: GO:0006886 - intracellular protein transport [Evidence IEA] AKAW2_80405S COG:T,U; EggNog:ENOG410PSYN AKAW2_80406A BUSCO:EOG092603SM; COG:D,Z; EggNog:ENOG410PFWD; InterPro:IPR009091,IPR002110,IPR000210,IPR020683, IPR011333,IPR000408,IPR036770; PFAM:PF13540,PF00415,PF00651,PF13637; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_80407A SECRETED:SignalP(1-25) AKAW2_80408S BUSCO:EOG09261V2P; COG:U; EggNog:ENOG410PK7X; InterPro:IPR036570,IPR018731,IPR040182; PFAM:PF10033; go_component: GO:1990316 - Atg1/ULK1 kinase complex [Evidence IEA]; go_process: GO:0000045 - autophagosome assembly [Evidence IEA]; go_process: GO:0006914 - autophagy [Evidence IEA] AKAW2_80409A BUSCO:EOG09260AEC; COG:S; EggNog:ENOG410PHMY; InterPro:IPR015943,IPR036322,IPR040382,IPR012580; PFAM:PF08159; go_component: GO:0005634 - nucleus [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_80410S COG:K; EggNog:ENOG410PGJE; InterPro:IPR021643,IPR009401,IPR041285; PFAM:PF11597,PF06333; go_component: GO:0016592 - mediator complex [Evidence IEA]; go_function: GO:0003712 - transcription coregulator activity [Evidence IEA]; go_process: GO:0006357 - regulation of transcription by RNA polymerase II [Evidence IEA] AKAW2_80412S BUSCO:EOG09264ZDJ; COG:S; EggNog:ENOG410PNFD; InterPro:IPR019398; PFAM:PF10273 AKAW2_80411A BUSCO:EOG09261PUF; COG:J; EggNog:ENOG410PI1B; InterPro:IPR027417,IPR000795,IPR003285,IPR004160, IPR004161,IPR009001,IPR009000; PFAM:PF00009,PF03143,PF03144; go_function: GO:0003747 - translation release factor activity [Evidence IEA]; go_function: GO:0003924 - GTPase activity [Evidence IEA]; go_function: GO:0005525 - GTP binding [Evidence IEA]; go_process: GO:0000288 - nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [Evidence IEA]; go_process: GO:0006415 - translational termination [Evidence IEA] AKAW2_80413S COG:S; EggNog:ENOG410PFRW; InterPro:IPR008812; PFAM:PF05508 AKAW2_80414A COG:S; EggNog:ENOG410PK3G; InterPro:IPR005607,IPR035925; PFAM:PF03909 AKAW2_80415A COG:S; EggNog:ENOG410PYTN AKAW2_80416S BUSCO:EOG09262Q8D; COG:C; EggNog:ENOG410Q1VT; InterPro:IPR017597,IPR029061,IPR001017; PFAM:PF00676; go_component: GO:0043231 - intracellular membrane-bounded organelle [Evidence IEA]; go_function: GO:0004739 - pyruvate dehydrogenase (acetyl-transferring) activity [Evidence IEA]; go_function: GO:0016624 - oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor [Evidence IEA]; go_process: GO:0006086 - acetyl-CoA biosynthetic process from pyruvate [Evidence IEA] AKAW2_80417S COG:S; EggNog:ENOG410PQQV; InterPro:IPR002767,IPR029756; PFAM:PF01910 AKAW2_80418S COG:S; EggNog:ENOG410PMVN; InterPro:IPR029063; PFAM:PF13649,PF13489,PF08242,PF08241,PF13847 AKAW2_80419S COG:S; EggNog:ENOG410PQWF AKAW2_80420A BUSCO:EOG092641M3; COG:O; EggNog:ENOG410PH45; InterPro:IPR024689,IPR029055,IPR001353,IPR023333, IPR035216; MEROPS:MER0000542; PFAM:PF12465; go_component: GO:0005839 - proteasome core complex [Evidence IEA]; go_process: GO:0051603 - proteolysis involved in cellular protein catabolic process [Evidence IEA] AKAW2_80421S COG:U,Y; EggNog:ENOG410QE08; InterPro:IPR015943,IPR026054; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_80422S COG:S; EggNog:ENOG410PSFU AKAW2_80423A COG:A; EggNog:ENOG410PJ6M; InterPro:IPR004087,IPR004088,IPR036612; PFAM:PF00013; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0003723 - RNA binding [Evidence IEA] AKAW2_80424S COG:S; EggNog:ENOG410PNXN; InterPro:IPR020993; go_component: GO:0005634 - nucleus [Evidence IEA]; go_process: GO:0051382 - kinetochore assembly [Evidence IEA] AKAW2_80425A BUSCO:EOG092613UB; COG:L; EggNog:ENOG410PHD9; InterPro:IPR004589,IPR002121,IPR036388,IPR018982, IPR027417,IPR036390,IPR001650,IPR032284,IPR010997, IPR014001,IPR011545,IPR002464; PFAM:PF16124,PF00176,PF00271,PF09382,PF00270, PF00570; go_function: GO:0000166 - nucleotide binding [Evidence IEA]; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0004386 - helicase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0043138 - 3'-5' DNA helicase activity [Evidence IEA]; go_process: GO:0006260 - DNA replication [Evidence IEA]; go_process: GO:0006281 - DNA repair [Evidence IEA]; go_process: GO:0006310 - DNA recombination [Evidence IEA]; go_process: GO:0044237 - cellular metabolic process [Evidence IEA] AKAW2_80426S COG:S; EggNog:ENOG410PFFT; InterPro:IPR025183,IPR015915; PFAM:PF13418,PF01344,PF13415,PF07646,PF13422; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_80427S COG:C; EggNog:ENOG410Q1BX; InterPro:IPR023210,IPR036812; PFAM:PF00248 AKAW2_80428A COG:K; EggNog:ENOG410PQG0 AKAW2_80429A COG:E; EggNog:ENOG410PK31; InterPro:IPR015424,IPR002129,IPR015421; PFAM:PF00282; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0016831 - carboxy-lyase activity [Evidence IEA]; go_function: GO:0030170 - pyridoxal phosphate binding [Evidence IEA]; go_process: GO:0019752 - carboxylic acid metabolic process [Evidence IEA] AKAW2_80430S COG:S; EggNog:ENOG410PKK2; InterPro:IPR002410,IPR000073,IPR029058; MEROPS:MER0001367; PFAM:PF00561; go_function: GO:0008233 - peptidase activity [Evidence IEA]; go_process: GO:0006508 - proteolysis [Evidence IEA] AKAW2_80431A BUSCO:EOG092624JL; COG:U; EggNog:ENOG410PJZ8; InterPro:IPR043971,IPR043970,IPR043972,IPR004353; PFAM:PF19036,PF19038,PF19037; go_process: GO:0006623 - protein targeting to vacuole [Evidence IEA]; go_process: GO:0016192 - vesicle-mediated transport [Evidence IEA] AKAW2_80432S BUSCO:EOG092605QM; COG:K; EggNog:ENOG410PHZ3; InterPro:IPR016024,IPR040314,IPR007249; PFAM:PF04118; TransMembrane:2 (o699-718i1113-1136o); go_process: GO:0006895 - Golgi to endosome transport [Evidence IEA] AKAW2_80433S COG:S; EggNog:ENOG410PQQF; TransMembrane:1 (n10-17c25/26o49-72i) AKAW2_80434S COG:S; EggNog:ENOG410PW5K; InterPro:IPR039723,IPR007529; PFAM:PF04438; go_process: GO:0006338 - chromatin remodeling [Evidence IEA]; go_process: GO:0043486 - histone exchange [Evidence IEA] AKAW2_80435A BUSCO:EOG0926235L; COG:T; EggNog:ENOG410PGX5; InterPro:IPR004299; PFAM:PF03062; TransMembrane:10 (i65-85o176-202i274-292o331-350i371-395o401-422i499- 516o522-543i555-582o588-611i) AKAW2_80436S COG:C; EggNog:ENOG410PRZ9; InterPro:IPR036046,IPR017968,IPR001792,IPR020456; PFAM:PF00708; go_function: GO:0003998 - acylphosphatase activity [Evidence IEA] AKAW2_80437S COG:C; EggNog:ENOG410PHGU; InterPro:IPR002680,IPR038659; PFAM:PF01786; TransMembrane:2 (i146-167o208-230i); go_function: GO:0009916 - alternative oxidase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_80438S COG:S; EggNog:ENOG410PM8Q AKAW2_80439S COG:S; EggNog:ENOG410PQU3; InterPro:IPR013889; PFAM:PF08580 AKAW2_80440A COG:K; EggNog:ENOG410PHBZ; InterPro:IPR000182,IPR016181; PFAM:PF00583; go_function: GO:0008080 - N-acetyltransferase activity [Evidence IEA] AKAW2_80441A BUSCO:EOG092652TN; COG:S; EggNog:ENOG410PQ8U; InterPro:IPR008381; PFAM:PF13233,PF05347; go_component: GO:0005739 - mitochondrion [Evidence IEA]; go_process: GO:0034553 - mitochondrial respiratory chain complex II assembly [Evidence IEA] AKAW2_80442S BUSCO:EOG09264XVU; COG:J; EggNog:ENOG410PKX9; InterPro:IPR002052,IPR029063; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0008168 - methyltransferase activity [Evidence IEA]; go_process: GO:0032259 - methylation [Evidence IEA] AKAW2_80443A BUSCO:EOG09265FL1; COG:A; EggNog:ENOG410PSD1; InterPro:IPR027141,IPR034102,IPR010920,IPR001163; PFAM:PF01423; go_process: GO:0000387 - spliceosomal snRNP assembly [Evidence IEA]; go_process: GO:0006396 - RNA processing [Evidence IEA] AKAW2_80444A COG:S; EggNog:ENOG410PJRB AKAW2_80445A COG:J; EggNog:ENOG410PHPV; InterPro:IPR027417,IPR000795; PFAM:PF00009; go_function: GO:0003924 - GTPase activity [Evidence IEA]; go_function: GO:0005525 - GTP binding [Evidence IEA] AKAW2_80446A COG:S; EggNog:ENOG410PR44 AKAW2_80448A COG:S; EggNog:ENOG410Q28J; TransMembrane:7 (o12-34i46-71o91-113i125-147o172-196i208-233o253-271i) AKAW2_80449A COG:S; EggNog:ENOG410Q2Y7; InterPro:IPR018306; PFAM:PF10544,PF13455; TransMembrane:2 (o381-403i410-430o) AKAW2_80450A COG:S; EggNog:ENOG410PY33; InterPro:IPR003615; PFAM:PF13391 AKAW2_80451A COG:S; EggNog:ENOG410PYUA; InterPro:IPR009288,IPR013024; PFAM:PF06094 AKAW2_80452A COG:U,Y; EggNog:ENOG410PFYX; InterPro:IPR016024,IPR021133,IPR034085,IPR040122, IPR001494; PFAM:PF02985,PF03810,PF13513; go_function: GO:0008536 - Ran GTPase binding [Evidence IEA]; go_process: GO:0006606 - protein import into nucleus [Evidence IEA]; go_process: GO:0006886 - intracellular protein transport [Evidence IEA] AKAW2_80453A COG:I; EggNog:ENOG410PFV1; InterPro:IPR003392,IPR000731,IPR032190; PFAM:PF12349,PF02460; TransMembrane:13 (n6-16c21/22o272-296i358-378o604-629i641-665o671-693i723- 742o748-773i832-849o1071-1092i1104-1127o1133-1155i1176- 1205o1217-1240i); go_component: GO:0016021 - integral component of membrane [Evidence IEA] AKAW2_80454S COG:D; EggNog:ENOG410PFYF; InterPro:IPR017441,IPR008271,IPR030616,IPR000719, IPR011009; PFAM:PF07714,PF00069; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_80455A COG:S; EggNog:ENOG410PXZG; InterPro:IPR032675 AKAW2_80456A COG:S; EggNog:ENOG410PXZG AKAW2_80457A COG:S; EggNog:ENOG410PXZG; InterPro:IPR001810,IPR036047,IPR032675; PFAM:PF12937; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_80458S COG:S; EggNog:ENOG410PIQV; TransMembrane:4 (i163-185o191-211i283-302o308-326i) AKAW2_80459S COG:S; EggNog:ENOG410PV4E; InterPro:IPR010730; PFAM:PF06985 AKAW2_80460S InterPro:IPR003480,IPR023213; PFAM:PF02458; go_function: GO:0016747 - transferase activity, transferring acyl groups other than amino-acyl groups [Evidence IEA] AKAW2_80461A COG:O; EggNog:ENOG410QE9I; InterPro:IPR001841,IPR002867,IPR017907,IPR031127, IPR013083; PFAM:PF01485; go_function: GO:0004842 - ubiquitin-protein transferase activity [Evidence IEA]; go_process: GO:0016567 - protein ubiquitination [Evidence IEA] AKAW2_80463A COG:I; EggNog:ENOG410PJJ4; InterPro:IPR006076,IPR036188,IPR002938; PFAM:PF01494,PF13450; TransMembrane:1 (i7-26o); go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0071949 - FAD binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_80464S COG:S; EggNog:ENOG410PI97 AKAW2_80465A COG:F; EggNog:ENOG410PNJY; InterPro:IPR029062 AKAW2_80467S COG:I; EggNog:ENOG410PK9F; InterPro:IPR042098,IPR003819; PFAM:PF02668; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_80468A BUSCO:EOG09260FKU; COG:D; EggNog:ENOG410PJJA; InterPro:IPR036317,IPR014786,IPR001373,IPR036388, IPR036390,IPR016158; PFAM:PF08672; go_function: GO:0031625 - ubiquitin protein ligase binding [Evidence IEA]; go_process: GO:0006511 - ubiquitin-dependent protein catabolic process [Evidence IEA] AKAW2_80469A COG:S; EggNog:ENOG410PRWV; InterPro:IPR013945; PFAM:PF08636; TransMembrane:2 (o20-41i48-66o); go_process: GO:0070072 - vacuolar proton-transporting V-type ATPase complex assembly [Evidence IEA] AKAW2_80470S COG:G; EggNog:ENOG410PMT3; InterPro:IPR005829,IPR005828,IPR003663,IPR036259, IPR020846; PFAM:PF00083; TransMembrane:6 (i47-69o93-113i125-145o151-172i184-203o215-238i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_80471S COG:S; EggNog:ENOG410PI62; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; TransMembrane:1 (o578-599i); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_80472A BUSCO:EOG0926587S; COG:K; EggNog:ENOG410PPJC; InterPro:IPR037212,IPR009244; PFAM:PF05983; go_component: GO:0016592 - mediator complex [Evidence IEA]; go_function: GO:0003712 - transcription coregulator activity [Evidence IEA]; go_process: GO:0006357 - regulation of transcription by RNA polymerase II [Evidence IEA] AKAW2_80473S COG:I; EggNog:ENOG410PJG4; InterPro:IPR036938,IPR043216,IPR000326; PFAM:PF01569; TransMembrane:6 (i34-54o80-101i113-130o180-197i209-230o236-255i); go_function: GO:0008195 - phosphatidate phosphatase activity [Evidence IEA]; go_process: GO:0006644 - phospholipid metabolic process [Evidence IEA] AKAW2_80474A COG:E; EggNog:ENOG410PH30; InterPro:IPR006076,IPR036188; PFAM:PF01266,PF00890; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_80475S COG:T; EggNog:ENOG410PFPV; InterPro:IPR004813,IPR004648; PFAM:PF03169; TransMembrane:13 (i82-100o106-129i192-213o219-238i250-266o323-346i393- 419o450-471i478-501o525-546i561-584o628-649i707-730o); go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_80476S COG:S; EggNog:ENOG410PQ85; InterPro:IPR036864,IPR021858,IPR001138; PFAM:PF00172,PF11951; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_80477A COG:S; EggNog:ENOG410PSPS AKAW2_80478A COG:S; EggNog:ENOG410PQIG; InterPro:IPR001810,IPR036047,IPR032675; PFAM:PF00646,PF12937; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_80479A TransMembrane:2 (n4-15c22/23o38-61i82-107o) AKAW2_80481S COG:S; EggNog:ENOG410Q2G6; antiSMASH:Cluster_8.6 AKAW2_80482S COG:S; EggNog:ENOG410PS0X; InterPro:IPR023213; antiSMASH:Cluster_8.6 AKAW2_80483A COG:L; EggNog:ENOG410PR0Z; InterPro:IPR020084,IPR020476,IPR000086,IPR015797; PFAM:PF00293; antiSMASH:Cluster_8.6; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_80484S COG:S; EggNog:ENOG410PGGW; InterPro:IPR038852; antiSMASH:Cluster_8.6 AKAW2_80485S BUSCO:EOG09264C3N; COG:Z; EggNog:ENOG410PIBY; InterPro:IPR037282,IPR042489,IPR042276,IPR017865, IPR002189; PFAM:PF01267; antiSMASH:Cluster_8.6; go_component: GO:0008290 - F-actin capping protein complex [Evidence IEA]; go_process: GO:0051016 - barbed-end actin filament capping [Evidence IEA] AKAW2_80487S COG:S; EggNog:ENOG410PSNE; InterPro:IPR008733; PFAM:PF05648; TransMembrane:3 (o129-152i173-194o200-218i); antiSMASH:Cluster_8.6; go_component: GO:0005779 - integral component of peroxisomal membrane [Evidence IEA]; go_process: GO:0016559 - peroxisome fission [Evidence IEA] AKAW2_80486A COG:S; EggNog:ENOG410PIVT; InterPro:IPR036864,IPR001138; PFAM:PF00172; antiSMASH:Cluster_8.6; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_80488A COG:S; EggNog:ENOG410PWQY; InterPro:IPR036291,IPR008030; PFAM:PF13460,PF05368; SMCOG1199:NmrA family protein; antiSMASH:Cluster_8.6 AKAW2_80489A antiSMASH:Cluster_8.6 AKAW2_80490S COG:Q; EggNog:ENOG410PIAK; InterPro:IPR000873,IPR009081,IPR036736,IPR036291, IPR020806,IPR013120,IPR042099,IPR020845; PFAM:PF00501,PF00550,PF01370,PF07993; SMCOG1002:AMP-dependent synthetase and ligase; antiSMASH:Cluster_8.6; go_function: GO:0031177 - phosphopantetheine binding [Evidence IEA] AKAW2_80491S COG:O; EggNog:ENOG410PFCG; InterPro:IPR001179,IPR023566,IPR041232; PFAM:PF17800,PF00254; antiSMASH:Cluster_8.6; go_function: GO:0003755 - peptidyl-prolyl cis-trans isomerase activity [Evidence IEA] AKAW2_80492S COG:T; EggNog:ENOG410PI2I; InterPro:IPR000719,IPR011009,IPR000961; PFAM:PF07714,PF00069; SMCOG1030:serine/threonine protein kinase; antiSMASH:Cluster_8.6; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0004674 - protein serine/threonine kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_80493A BUSCO:EOG09260BL6; COG:K; EggNog:ENOG410PHB2; InterPro:IPR040240,IPR022591; PFAM:PF12157; antiSMASH:Cluster_8.6 AKAW2_80494A CAZy:AA3; COG:E; EggNog:ENOG410PJ6X; InterPro:IPR012132,IPR036188,IPR027424,IPR000172, IPR007867; PFAM:PF00732,PF05199; antiSMASH:Cluster_8.6; go_function: GO:0016614 - oxidoreductase activity, acting on CH-OH group of donors [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_80495A COG:E; EggNog:ENOG410PJ6X; InterPro:IPR012132,IPR000172,IPR036188; SECRETED:SignalP(1-17); antiSMASH:Cluster_8.6; go_function: GO:0016614 - oxidoreductase activity, acting on CH-OH group of donors [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_80496A CAZy:AA3; COG:E; EggNog:ENOG410PJHS; InterPro:IPR012132,IPR036188,IPR000172,IPR007867; PFAM:PF05199,PF00732; antiSMASH:Cluster_8.6; go_function: GO:0016614 - oxidoreductase activity, acting on CH-OH group of donors [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_80497S COG:Z; EggNog:ENOG410QEG6; InterPro:IPR000845,IPR035994,IPR027417,IPR002182; PFAM:PF05729,PF00931,PF01048; SECRETED:SignalP(1-23); go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0043531 - ADP binding [Evidence IEA]; go_process: GO:0009116 - nucleoside metabolic process [Evidence IEA] AKAW2_80498A BUSCO:EOG0926306O; COG:S; EggNog:ENOG410PITT; InterPro:IPR019012,IPR029063; PFAM:PF09445,PF02475; go_function: GO:0008168 - methyltransferase activity [Evidence IEA]; go_process: GO:0001510 - RNA methylation [Evidence IEA]; go_process: GO:0009452 - 7-methylguanosine RNA capping [Evidence IEA] AKAW2_80499S BUSCO:EOG09262V9N; COG:U; EggNog:ENOG410PKK9; InterPro:IPR036034,IPR024958,IPR007583; PFAM:PF04495; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_80500A COG:M; EggNog:ENOG410PNIR; InterPro:IPR002110,IPR036770,IPR007111,IPR020683; PFAM:PF05729,PF12796,PF00023,PF13637,PF13857; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_80501S COG:Q; EggNog:ENOG410PKC8; InterPro:IPR001128,IPR017972,IPR002401,IPR036396; PFAM:PF00067; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_80502S TransMembrane:3 (n9-20c24/25o60-79i100-121o156-178i) AKAW2_80503A COG:S; EggNog:ENOG410PP9A; InterPro:IPR033181,IPR019166; PFAM:PF09769; go_component: GO:0061617 - MICOS complex [Evidence IEA]; go_process: GO:0042407 - cristae formation [Evidence IEA] AKAW2_80504S BUSCO:EOG09260JJW; COG:O; EggNog:ENOG410PGPG; InterPro:IPR033851,IPR024077,IPR001567; MEROPS:MER0001156; PFAM:PF01432; go_component: GO:0005759 - mitochondrial matrix [Evidence IEA]; go_function: GO:0004222 - metalloendopeptidase activity [Evidence IEA]; go_process: GO:0006508 - proteolysis [Evidence IEA]; go_process: GO:0006627 - protein processing involved in protein targeting to mitochondrion [Evidence IEA] AKAW2_80506A COG:S; EggNog:ENOG410PQKZ; InterPro:IPR029605 AKAW2_80507A COG:S; EggNog:ENOG410PZH6 AKAW2_80508S COG:O; EggNog:ENOG410PJ68; InterPro:IPR043170,IPR004327,IPR037218; PFAM:PF03095; go_function: GO:0019211 - phosphatase activator activity [Evidence IEA] AKAW2_80509A COG:S; EggNog:ENOG410PGCJ; InterPro:IPR007590; PFAM:PF04502 AKAW2_80510A COG:S; EggNog:ENOG410Q1Z5 AKAW2_80511S COG:S; EggNog:ENOG410PM8E AKAW2_80512S COG:S; EggNog:ENOG410Q2TJ AKAW2_80513A COG:S; EggNog:ENOG410PXG6; InterPro:IPR014710,IPR011051,IPR025979; PFAM:PF12973 AKAW2_80514A COG:S; EggNog:ENOG410Q1M6; InterPro:IPR007219; TransMembrane:1 (o346-368i); go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA] AKAW2_80516A COG:Q; EggNog:ENOG410PNVS; InterPro:IPR002347,IPR036291; PFAM:PF00106,PF13561,PF08659,PF01370; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_80515S COG:C; EggNog:ENOG410PWHK; InterPro:IPR016166,IPR006094,IPR036318; PFAM:PF01565; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_function: GO:0071949 - FAD binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_80517A CAZy:GH18; COG:G; EggNog:ENOG410PKNR; InterPro:IPR036861,IPR011583,IPR029226,IPR029070, IPR001223,IPR017853,IPR018392,IPR001002,IPR001579, IPR036779; PFAM:PF00704,PF14856; SECRETED:SignalP(1-24); go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_function: GO:0008061 - chitin binding [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_80518A COG:S; EggNog:ENOG410PZ9X; SECRETED:SignalP(1-21); TransMembrane:1 (n8-16c21/22o256-275i) AKAW2_80519S CAZy:CBM50; COG:S; EggNog:ENOG410PVRH; InterPro:IPR018392,IPR036779; PFAM:PF01476; SECRETED:SignalP(1-18) AKAW2_80520A InterPro:IPR011009 AKAW2_80522S COG:S; EggNog:ENOG410Q1Z5 AKAW2_80523A COG:S; EggNog:ENOG410PVMX; InterPro:IPR036890 AKAW2_80525S COG:C; EggNog:ENOG410PIXQ; InterPro:IPR011032,IPR020843,IPR013154,IPR036291; PFAM:PF08240; TransMembrane:2 (i118-136o156-173i); go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_80526A COG:Q; EggNog:ENOG410PK0J; InterPro:IPR006680,IPR011059,IPR032466; MEROPS:MER0005900; PFAM:PF01979; go_function: GO:0016787 - hydrolase activity [Evidence IEA]; go_function: GO:0016810 - hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [Evidence IEA] AKAW2_80527S COG:G; EggNog:ENOG410QDIJ; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i40-57o86-104i111-134o140-161i170-192o204-224i272- 296o308-330i337-356o362-384i396-417o429-449i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_80528S COG:S; EggNog:ENOG410PTDD AKAW2_80529A COG:S; EggNog:ENOG410PMYE; InterPro:IPR013087 AKAW2_80530S COG:S; EggNog:ENOG410Q4KH AKAW2_80531A COG:I; EggNog:ENOG410PFIS; InterPro:IPR037997; TransMembrane:6 (o47-66i113-130o136-157i169-190o226-245i257-277o); go_function: GO:0004143 - diacylglycerol kinase activity [Evidence IEA] AKAW2_80532A COG:G; EggNog:ENOG410PJTS; InterPro:IPR036259; TransMembrane:4 (i21-45o57-75i87-108o192-212i) AKAW2_80533A COG:Q; EggNog:ENOG410PGYE; InterPro:IPR001128,IPR017972,IPR002401,IPR036396; PFAM:PF00067; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_80536S COG:S; EggNog:ENOG410PNAW; InterPro:IPR011009 AKAW2_80537A COG:I; EggNog:ENOG410PWJI; InterPro:IPR036291,IPR026055,IPR013120; PFAM:PF07993; TransMembrane:1 (i9-28o); go_function: GO:0080019 - fatty-acyl-CoA reductase (alcohol-forming) activity [Evidence IEA] AKAW2_80538A CAZy:CBM50; COG:G; EggNog:ENOG410Q1MZ; InterPro:IPR018392,IPR036779; PFAM:PF01476; SECRETED:SignalP(1-17) AKAW2_80539A COG:S; EggNog:ENOG410Q1D0; InterPro:IPR002110,IPR036770,IPR020683; PFAM:PF12796; TransMembrane:1 (o293-314i); go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_80541S COG:I; EggNog:ENOG410PQJZ; InterPro:IPR011009 AKAW2_80542A COG:S; EggNog:ENOG410PSY7; InterPro:IPR014347 AKAW2_80543A COG:M; EggNog:ENOG410Q2I7; InterPro:IPR002110,IPR027417,IPR036770,IPR020683, IPR031359; PFAM:PF12796,PF00023,PF13637,PF17100; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_80545A CAZy:GH3; COG:G; EggNog:ENOG410PM1F; InterPro:IPR017853,IPR019800,IPR036962,IPR002772, IPR036881,IPR026891,IPR013783,IPR001764; PFAM:PF14310,PF00933,PF01915; SECRETED:SignalP(1-21); go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_80546A COG:S; EggNog:ENOG410PQAJ AKAW2_80547A BUSCO:EOG09263KB4; COG:F; EggNog:ENOG410PFY7; InterPro:IPR000845,IPR018099,IPR035994,IPR010044; PFAM:PF01048; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0016763 - transferase activity, transferring pentosyl groups [Evidence IEA]; go_function: GO:0017061 - S-methyl-5-thioadenosine phosphorylase activity [Evidence IEA]; go_process: GO:0009116 - nucleoside metabolic process [Evidence IEA] AKAW2_80548A COG:G; EggNog:ENOG410PJ56; InterPro:IPR006183,IPR036291,IPR006114,IPR006115, IPR008927,IPR013328,IPR006113; PFAM:PF03446,PF00393; go_function: GO:0004616 - phosphogluconate dehydrogenase (decarboxylating) activity [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0050661 - NADP binding [Evidence IEA]; go_process: GO:0006098 - pentose-phosphate shunt [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_80549S COG:G; EggNog:ENOG410PJ4Y; InterPro:IPR013022,IPR036237; PFAM:PF01261 AKAW2_80550A COG:E; EggNog:ENOG410PG3T; InterPro:IPR015590,IPR005931,IPR029510,IPR016160, IPR016161,IPR016162,IPR016163; PFAM:PF00171; go_function: GO:0003842 - 1-pyrroline-5-carboxylate dehydrogenase activity [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0016620 - oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Evidence IEA]; go_process: GO:0010133 - proline catabolic process to glutamate [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_80551A COG:E; EggNog:ENOG410QDM5; InterPro:IPR004841; PFAM:PF13520,PF00324; TransMembrane:10 (i53-72o78-98i132-154o160-182i194-212o283-304i385-405o411- 435i456-479o485-506i); go_component: GO:0016020 - membrane [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_80552S COG:E; EggNog:ENOG410PGMR; InterPro:IPR002872,IPR015659,IPR029041; PFAM:PF01619; go_function: GO:0004657 - proline dehydrogenase activity [Evidence IEA]; go_process: GO:0006562 - proline catabolic process [Evidence IEA] AKAW2_80553S COG:E; EggNog:ENOG410PHTM; InterPro:IPR036291,IPR003462,IPR023401; PFAM:PF02423 AKAW2_80554S COG:K; EggNog:ENOG410PJAX; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_80555A COG:S; EggNog:ENOG410PJXP; InterPro:IPR015158,IPR037393; PFAM:PF09073 AKAW2_80556A COG:C; EggNog:ENOG410PGKA; InterPro:IPR020396,IPR001268,IPR010218,IPR037232; PFAM:PF00329; go_function: GO:0008137 - NADH dehydrogenase (ubiquinone) activity [Evidence IEA]; go_function: GO:0016651 - oxidoreductase activity, acting on NAD(P)H [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_80557S BUSCO:EOG09260P5R; COG:K; EggNog:ENOG410PFB8; InterPro:IPR035979,IPR034261,IPR003954,IPR012677, IPR039780,IPR013083; PFAM:PF14570; go_component: GO:0030014 - CCR4-NOT complex [Evidence IEA]; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0004842 - ubiquitin-protein transferase activity [Evidence IEA] AKAW2_80558A COG:Q; EggNog:ENOG410PPEM; InterPro:IPR036291,IPR020843,IPR013154,IPR011032; PFAM:PF08240; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_80559A COG:S; EggNog:ENOG410PU9N AKAW2_80560A COG:S; EggNog:ENOG410PVHM; InterPro:IPR008949 AKAW2_80561S COG:S; EggNog:ENOG410PMHP; InterPro:IPR008930 AKAW2_80562A COG:Q; EggNog:ENOG410PPIZ; InterPro:IPR036291,IPR002347; PFAM:PF00106,PF13561; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_80563S COG:G; EggNog:ENOG410PJKR; InterPro:IPR011701,IPR036259; PFAM:PF07690; TransMembrane:8 (i21-41o53-73i94-118o133-153i160-181o187-210i222-242o254- 272i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_80564S COG:S; EggNog:ENOG410PUYG; InterPro:IPR002935,IPR029063; PFAM:PF13578,PF01596; go_function: GO:0008171 - O-methyltransferase activity [Evidence IEA] AKAW2_80565S COG:S; EggNog:ENOG410PVBT; InterPro:IPR036864,IPR001138; PFAM:PF00172; TransMembrane:1 (i204-229o); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_80566A COG:E; EggNog:ENOG410PVP2; InterPro:IPR036052,IPR001926; PFAM:PF00291 AKAW2_80567S COG:G; EggNog:ENOG410QDAP; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:11 (i29-53o73-98i105-130o136-156i163-183o195-216i254-275o320- 341i353-372o392-412i424-445o); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_80568A COG:G; EggNog:ENOG410PIWB; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:11 (o141-164i176-197o203-221i228-250o262-282i335-360o372- 392i399-419o425-447i459-481o487-510i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_80569A COG:T; EggNog:ENOG410PKRQ; InterPro:IPR004839,IPR015424,IPR015421,IPR015422; PFAM:PF00155; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0030170 - pyridoxal phosphate binding [Evidence IEA]; go_process: GO:0009058 - biosynthetic process [Evidence IEA] AKAW2_80570S COG:G; EggNog:ENOG410PK4Z; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i46-67o79-100i107-126o166-190i197-218o238-258i270- 290o310-335i347-368o374-393i405-426o482-503i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_80571A COG:E,I; EggNog:ENOG410PHUI; InterPro:IPR023631,IPR036928 AKAW2_80572A InterPro:IPR007837,IPR034660; PFAM:PF05163,PF12867 AKAW2_80573A COG:K; EggNog:ENOG410PGMJ; InterPro:IPR007219; PFAM:PF04082; TransMembrane:1 (o435-455i); go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA] AKAW2_80574A COG:G; EggNog:ENOG410PMBP; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; SECRETED:SignalP(1-33); SMCOG1005:Drug resistance transporter, EmrB/QacA; TransMembrane:13 (i12-33o53-72i84-109o115-134i141-159o171-190i210-229o241- 259i280-301o321-340i347-366o372-391i491-508o); antiSMASH:Cluster_8.8; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_80575A COG:S; EggNog:ENOG410PYNJ; TransMembrane:7 (o24-45i57-82o102-121i142-163o203-222i234-256o276-298i); antiSMASH:Cluster_8.8 AKAW2_80576S COG:C; EggNog:ENOG410PVU7; InterPro:IPR011032,IPR020843,IPR013154,IPR036291; PFAM:PF08240; SMCOG1028:crotonyl-CoA reductase / alcohol dehydrogenase; antiSMASH:Cluster_8.8; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_80577A COG:S; EggNog:ENOG410PTAV; InterPro:IPR011008,IPR009799; PFAM:PF07110; antiSMASH:Cluster_8.8; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA] AKAW2_80578S COG:I; EggNog:ENOG410PJU8; InterPro:IPR016036,IPR016035,IPR016039,IPR018201, IPR042104,IPR014030,IPR014031,IPR013968,IPR020845, IPR001227,IPR032821,IPR023213,IPR014043,IPR020806, IPR020807,IPR001242,IPR020841,IPR000873,IPR009081, IPR029063,IPR036736,IPR036291,IPR013120,IPR042099; PFAM:PF16197,PF00109,PF00668,PF00550,PF14765, PF02801,PF00698,PF00501,PF07993,PF08659,PF01370,PF00106; SMCOG1093:Beta-ketoacyl synthase; antiSMASH:Cluster_8.8; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein] synthase activity [Evidence IEA]; go_function: GO:0016740 - transferase activity [Evidence IEA]; go_function: GO:0016746 - transferase activity, transferring acyl groups [Evidence IEA]; go_function: GO:0031177 - phosphopantetheine binding [Evidence IEA]; go_process: GO:0006633 - fatty acid biosynthetic process [Evidence IEA] AKAW2_80579A COG:S; EggNog:ENOG410Q1B4; SECRETED:SignalP(1-16); antiSMASH:Cluster_8.8 AKAW2_80580A COG:S; EggNog:ENOG410PIK0; InterPro:IPR010775; PFAM:PF07103; TransMembrane:2 (o6-21i28-53o); antiSMASH:Cluster_8.8 AKAW2_80581S COG:Q; EggNog:ENOG410Q1KV; InterPro:IPR020946,IPR036188; SMCOG1092:hypothetical protein; TransMembrane:1 (i129-149o); antiSMASH:Cluster_8.8; go_function: GO:0004499 - N,N-dimethylaniline monooxygenase activity [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_function: GO:0050661 - NADP binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_80582A CAZy:GH2; COG:G; EggNog:ENOG410PGS5; InterPro:IPR036156,IPR017853,IPR006102,IPR008979, IPR013783,IPR041625,IPR041447; PFAM:PF17753,PF00703,PF17786; SECRETED:SignalP(1-21); antiSMASH:Cluster_8.8; go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_80583S COG:S; EggNog:ENOG410QDNZ; InterPro:IPR010730; PFAM:PF06985; antiSMASH:Cluster_8.8 AKAW2_80584S COG:T; EggNog:ENOG410PVXJ; InterPro:IPR000719,IPR011009,IPR017441; PFAM:PF00069; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_80585S BUSCO:EOG09264A8D; COG:H; EggNog:ENOG410PH01; InterPro:IPR023576,IPR004033,IPR029063; PFAM:PF13649,PF13489,PF01209,PF08242,PF08241, PF13847; go_function: GO:0008168 - methyltransferase activity [Evidence IEA] AKAW2_80586S COG:M; EggNog:ENOG410PG4A; InterPro:IPR035474,IPR001347; PFAM:PF01380; go_function: GO:0097367 - carbohydrate derivative binding [Evidence IEA]; go_process: GO:1901135 - carbohydrate derivative metabolic process [Evidence IEA] AKAW2_80587A COG:H; EggNog:ENOG410PF81; InterPro:IPR004821,IPR005248,IPR014729; PFAM:PF01467; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0016779 - nucleotidyltransferase activity [Evidence IEA]; go_process: GO:0009058 - biosynthetic process [Evidence IEA]; go_process: GO:0009435 - NAD biosynthetic process [Evidence IEA] AKAW2_80588S COG:O; EggNog:ENOG410PGIG; InterPro:IPR035983,IPR000569,IPR011989,IPR016024; PFAM:PF00632; go_function: GO:0004842 - ubiquitin-protein transferase activity [Evidence IEA] AKAW2_80589A COG:S; EggNog:ENOG410Q2YC; InterPro:IPR029069,IPR006683; PFAM:PF03061 AKAW2_80590A COG:A; EggNog:ENOG410PGCH; InterPro:IPR027417,IPR001650,IPR014014,IPR014001, IPR011545,IPR000629; PFAM:PF00270,PF00271; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0004386 - helicase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA] AKAW2_80591S COG:J; EggNog:ENOG410PID8; InterPro:IPR028590,IPR015507,IPR002877,IPR029063; PFAM:PF01728; go_function: GO:0008168 - methyltransferase activity [Evidence IEA]; go_function: GO:0008175 - tRNA methyltransferase activity [Evidence IEA]; go_process: GO:0001510 - RNA methylation [Evidence IEA]; go_process: GO:0008033 - tRNA processing [Evidence IEA]; go_process: GO:0032259 - methylation [Evidence IEA] AKAW2_80592A COG:E; EggNog:ENOG410PH6J; InterPro:IPR017938,IPR003097,IPR001433,IPR017927, IPR002869,IPR001709,IPR023173,IPR019752,IPR009014, IPR039261; PFAM:PF01558,PF00175,PF00667; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0016903 - oxidoreductase activity, acting on the aldehyde or oxo group of donors [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_80593S COG:T; EggNog:ENOG410PPS2; InterPro:IPR036291,IPR016040; PFAM:PF13460 AKAW2_80594A COG:S; EggNog:ENOG410PT5N AKAW2_80596S COG:S; EggNog:ENOG410PR5P AKAW2_80598A COG:O; EggNog:ENOG410PIQW; InterPro:IPR029055,IPR016050,IPR034647,IPR001353, IPR023332,IPR000426; MEROPS:MER0000554; PFAM:PF00227; go_component: GO:0005839 - proteasome core complex [Evidence IEA]; go_component: GO:0019773 - proteasome core complex, alpha-subunit complex [Evidence IEA]; go_function: GO:0004298 - threonine-type endopeptidase activity [Evidence IEA]; go_process: GO:0006511 - ubiquitin-dependent protein catabolic process [Evidence IEA]; go_process: GO:0051603 - proteolysis involved in cellular protein catabolic process [Evidence IEA] AKAW2_80599S COG:K; EggNog:ENOG410QDG5; InterPro:IPR036020,IPR039726,IPR036517,IPR002713, IPR001202; PFAM:PF00397,PF01846; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0045292 - mRNA cis splicing, via spliceosome [Evidence IEA] AKAW2_80600A COG:S; EggNog:ENOG410QEIT AKAW2_80601S COG:K; EggNog:ENOG410QDQ7; InterPro:IPR036575,IPR019787,IPR019786,IPR003618, IPR011011,IPR012921,IPR001965,IPR013083; PFAM:PF00628,PF07500,PF07744; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA] AKAW2_80602A BUSCO:EOG09264D7Y; COG:A; EggNog:ENOG410PIXG; InterPro:IPR004882; PFAM:PF03194; go_component: GO:0005685 - U1 snRNP [Evidence IEA]; go_function: GO:0003729 - mRNA binding [Evidence IEA]; go_process: GO:0006376 - mRNA splice site selection [Evidence IEA] AKAW2_80603S BUSCO:EOG09261LEU; COG:G; EggNog:ENOG410PIR6; InterPro:IPR007245; PFAM:PF04113; SECRETED:SignalP(1-21); TransMembrane:1 (n4-15c21/22o531-553i); go_component: GO:0042765 - GPI-anchor transamidase complex [Evidence IEA]; go_process: GO:0016255 - attachment of GPI anchor to protein [Evidence IEA] AKAW2_80604A COG:S; EggNog:ENOG410Q28G AKAW2_80605A COG:S; EggNog:ENOG410PSIH; InterPro:IPR039764; go_function: GO:0003723 - RNA binding [Evidence IEA] AKAW2_80606A COG:S; EggNog:ENOG410PTMG; InterPro:IPR007292; SECRETED:SignalP(1-30); go_process: GO:0000742 - karyogamy involved in conjugation with cellular fusion [Evidence IEA]; go_process: GO:0048288 - nuclear membrane fusion involved in karyogamy [Evidence IEA] AKAW2_80607S COG:J; EggNog:ENOG410PNE9; InterPro:IPR020040,IPR019906,IPR036789,IPR000702, IPR002358; PFAM:PF00347; go_component: GO:0005840 - ribosome [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_function: GO:0019843 - rRNA binding [Evidence IEA]; go_process: GO:0006412 - translation [Evidence IEA] AKAW2_80608A BUSCO:EOG09262HP3; COG:F,P; EggNog:ENOG410PFFG; InterPro:IPR020550,IPR000760,IPR020583,IPR006239; PFAM:PF00459; TransMembrane:1 (o20-40i); go_function: GO:0008441 - 3'(2'),5'-bisphosphate nucleotidase activity [Evidence IEA]; go_process: GO:0006790 - sulfur compound metabolic process [Evidence IEA]; go_process: GO:0046854 - phosphatidylinositol phosphorylation [Evidence IEA]; go_process: GO:0046855 - inositol phosphate dephosphorylation [Evidence IEA] AKAW2_80610S BUSCO:EOG09262YQG; COG:U; EggNog:ENOG410PGIX; InterPro:IPR002014,IPR044103,IPR008942; PFAM:PF00790; go_process: GO:0006886 - intracellular protein transport [Evidence IEA]; go_process: GO:0006897 - endocytosis [Evidence IEA]; go_process: GO:0007015 - actin filament organization [Evidence IEA] AKAW2_80611A COG:D,P; EggNog:ENOG410PGV0; InterPro:IPR036551,IPR003382; PFAM:PF02441; go_function: GO:0003824 - catalytic activity [Evidence IEA] AKAW2_80612A COG:D,P; EggNog:ENOG410PGV0; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:14 (i54-76o82-101i122-141o147-167i179-202o208-233i245- 264o276-295i315-338o350-371i383-403o409-435i447-469o518- 537i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_80614A COG:S; EggNog:ENOG410PT4G; InterPro:IPR018555; PFAM:PF09428 AKAW2_80615S COG:S; EggNog:ENOG410PTKJ; InterPro:IPR028209; PFAM:PF15454; go_component: GO:0031902 - late endosome membrane [Evidence IEA]; go_component: GO:0045121 - membrane raft [Evidence IEA]; go_component: GO:0071986 - Ragulator complex [Evidence IEA]; go_process: GO:0001919 - regulation of receptor recycling [Evidence IEA]; go_process: GO:0007040 - lysosome organization [Evidence IEA]; go_process: GO:0016197 - endosomal transport [Evidence IEA]; go_process: GO:0032008 - positive regulation of TOR signaling [Evidence IEA]; go_process: GO:0042632 - cholesterol homeostasis [Evidence IEA]; go_process: GO:0043410 - positive regulation of MAPK cascade [Evidence IEA]; go_process: GO:0071230 - cellular response to amino acid stimulus [Evidence IEA] AKAW2_80616A BUSCO:EOG09264Z1B; COG:O; EggNog:ENOG410Q09Y; InterPro:IPR016135,IPR023313,IPR000608; PFAM:PF00179 AKAW2_80618S BUSCO:EOG09265EKJ; COG:O; EggNog:ENOG410PRAB; InterPro:IPR029071,IPR007242; PFAM:PF04110; go_component: GO:0005737 - cytoplasm [Evidence IEA]; go_process: GO:0000045 - autophagosome assembly [Evidence IEA] AKAW2_80619A BUSCO:EOG09263FTE; COG:H; EggNog:ENOG410PHZX; InterPro:IPR003700,IPR015813,IPR040442; PFAM:PF02548; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0003864 - 3-methyl-2-oxobutanoate hydroxymethyltransferase activity [Evidence IEA]; go_process: GO:0015940 - pantothenate biosynthetic process [Evidence IEA] AKAW2_80620A COG:L; EggNog:ENOG410PFPA; InterPro:IPR036420,IPR038545,IPR006572,IPR013939; PFAM:PF07535,PF08630; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA] AKAW2_80621A BUSCO:EOG09261XGL; COG:E; EggNog:ENOG410PH1D; InterPro:IPR000994,IPR029149,IPR036005,IPR007865; MEROPS:MER0013463; PFAM:PF05195,PF00557; go_function: GO:0030145 - manganese ion binding [Evidence IEA]; go_function: GO:0070006 - metalloaminopeptidase activity [Evidence IEA] AKAW2_80622S COG:C; EggNog:ENOG410PNH4; InterPro:IPR024747,IPR012349; PFAM:PF12900 AKAW2_80623S COG:B,K; EggNog:ENOG410PHX8; InterPro:IPR026590,IPR026591,IPR027546,IPR029035, IPR003000; PFAM:PF02146; go_function: GO:0036054 - protein-malonyllysine demalonylase activity [Evidence IEA]; go_function: GO:0036055 - protein-succinyllysine desuccinylase activity [Evidence IEA]; go_function: GO:0070403 - NAD+ binding [Evidence IEA] AKAW2_80624S COG:K,L; EggNog:ENOG410QDFW; InterPro:IPR038718,IPR000330,IPR027417,IPR014001, IPR001650; PFAM:PF00176,PF00271,PF04851; go_function: GO:0005524 - ATP binding [Evidence IEA] AKAW2_80625A COG:S; EggNog:ENOG410PNJC; InterPro:IPR011009,IPR002575,IPR008266; PFAM:PF01636; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_80626S COG:D; EggNog:ENOG410PMJR; InterPro:IPR027417 AKAW2_80627S COG:D; EggNog:ENOG410PMJR; InterPro:IPR002110,IPR020683,IPR036770,IPR000719, IPR011009; PFAM:PF12796,PF00023,PF07714,PF00069,PF13637, PF13606; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_80628S COG:Q; EggNog:ENOG410PGYE; InterPro:IPR002402,IPR002974,IPR036396,IPR017972, IPR001128; PFAM:PF00067; go_function: GO:0004497 - monooxygenase activity [Evidence IEA]; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0016712 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_80629A COG:S; EggNog:ENOG410PRG9; InterPro:IPR000073,IPR029058; PFAM:PF12697 AKAW2_80630A COG:S; EggNog:ENOG410PWW3; TransMembrane:7 (o15-37i49-66o86-116i128-150o170-194i206-228o248-274i) AKAW2_80631A SECRETED:SignalP(1-20) AKAW2_80632S COG:S; EggNog:ENOG410PXZE; InterPro:IPR021765; PFAM:PF11807; TransMembrane:1 (i44-64o); go_process: GO:0043386 - mycotoxin biosynthetic process [Evidence IEA] AKAW2_80633A COG:S; EggNog:ENOG410PT5P; InterPro:IPR029063; PFAM:PF13489,PF08241,PF13649 AKAW2_80634A COG:T; EggNog:ENOG410PW4Q; InterPro:IPR000719,IPR011009; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_80635A CAZy:GH146; COG:S; EggNog:ENOG410PV0A; InterPro:IPR012878; PFAM:PF07944 AKAW2_80636A COG:S; EggNog:ENOG410PHT6; InterPro:IPR008979,IPR013736; go_function: GO:0008239 - dipeptidyl-peptidase activity [Evidence IEA] AKAW2_80637A COG:S; EggNog:ENOG410PYU2 AKAW2_80638A COG:O; EggNog:ENOG410PI6E; InterPro:IPR027417,IPR003593,IPR003959; PFAM:PF00004; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA] AKAW2_80639S COG:S; EggNog:ENOG410PQK6; antiSMASH:Cluster_8.9 AKAW2_80640A SECRETED:SignalP(1-16); antiSMASH:Cluster_8.9 AKAW2_80641S COG:S; EggNog:ENOG410PXC3; InterPro:IPR021765; PFAM:PF11807; TransMembrane:1 (o50-73i); antiSMASH:Cluster_8.9; go_process: GO:0043386 - mycotoxin biosynthetic process [Evidence IEA] AKAW2_80642S COG:S; EggNog:ENOG410PXC3; InterPro:IPR021765; antiSMASH:Cluster_8.9; go_process: GO:0043386 - mycotoxin biosynthetic process [Evidence IEA] AKAW2_80643A COG:C; EggNog:ENOG410PVX7; InterPro:IPR015955,IPR001236,IPR036291,IPR001557, IPR010097,IPR022383; PFAM:PF00056,PF02866; antiSMASH:Cluster_8.9; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0016616 - oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Evidence IEA]; go_function: GO:0030060 - L-malate dehydrogenase activity [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA]; go_process: GO:0006099 - tricarboxylic acid cycle [Evidence IEA]; go_process: GO:0019752 - carboxylic acid metabolic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_80644S COG:S; EggNog:ENOG410PXRE; InterPro:IPR038305,IPR029498; PFAM:PF14479; antiSMASH:Cluster_8.9 AKAW2_80645A COG:C; EggNog:ENOG410PFMM; InterPro:IPR006140,IPR036291,IPR006139,IPR029753, IPR029752; PFAM:PF00389,PF02826; SMCOG1072:dehydrogenase; antiSMASH:Cluster_8.9; go_function: GO:0016616 - oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Evidence IEA]; go_function: GO:0051287 - NAD binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_80646S COG:G; EggNog:ENOG410PKV4; InterPro:IPR005828,IPR003663,IPR036259,IPR020846; PFAM:PF00083,PF07690; SMCOG1169:sugar transport protein; TransMembrane:11 (o6-26i38-57o63-84i96-116o128-149i215-237o257-278i285- 308o314-341i353-371o383-404i); antiSMASH:Cluster_8.9; go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_80647S COG:G; EggNog:ENOG410Q2VM; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; SMCOG1106:major facilitator transporter; TransMembrane:12 (i54-75o95-114i121-142o148-170i182-203o209-231i287- 306o326-345i365-386o392-414i426-448o460-483i); antiSMASH:Cluster_8.9; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_80648A COG:I; EggNog:ENOG410PM0W; InterPro:IPR032088,IPR016035,IPR009081,IPR030918, IPR001227,IPR014043,IPR036736,IPR018201,IPR016039, IPR032821,IPR020806,IPR042104,IPR014030,IPR014031, IPR020841; PFAM:PF16197,PF00109,PF16073,PF02801,PF00698, PF00550; SMCOG1093:Beta-ketoacyl synthase; TransMembrane:2 (o986-1007i1019-1038o); antiSMASH:Cluster_8.9; go_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein] synthase activity [Evidence IEA]; go_function: GO:0016740 - transferase activity [Evidence IEA]; go_function: GO:0016746 - transferase activity, transferring acyl groups [Evidence IEA]; go_function: GO:0031177 - phosphopantetheine binding [Evidence IEA]; go_process: GO:0006633 - fatty acid biosynthetic process [Evidence IEA] AKAW2_80649S COG:S; EggNog:ENOG410PJX9; InterPro:IPR001279,IPR036388,IPR036866; PFAM:PF00753; SMCOG1170:metallo-beta-lactamase family protein; antiSMASH:Cluster_8.9 AKAW2_80650A COG:S; EggNog:ENOG410PQ7W; InterPro:IPR036188,IPR002938; SMCOG1087:hypothetical protein; antiSMASH:Cluster_8.9; go_function: GO:0071949 - FAD binding [Evidence IEA] AKAW2_80651S COG:Q; EggNog:ENOG410PQMA; InterPro:IPR029063,IPR025714,IPR016584; PFAM:PF13847; TransMembrane:1 (o37-57i); antiSMASH:Cluster_8.9; go_function: GO:0008168 - methyltransferase activity [Evidence IEA] AKAW2_80652A COG:K; EggNog:ENOG410PVEH; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; antiSMASH:Cluster_8.9; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_80653S antiSMASH:Cluster_8.9 AKAW2_80654S COG:S; EggNog:ENOG410PPJK; InterPro:IPR003719; PFAM:PF02567; antiSMASH:Cluster_8.9; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_process: GO:0009058 - biosynthetic process [Evidence IEA] AKAW2_80655S COG:T; EggNog:ENOG410PHU4; InterPro:IPR017441,IPR008271,IPR000719,IPR011009; PFAM:PF07714,PF00069; SMCOG1030:serine/threonine protein kinase; antiSMASH:Cluster_8.9; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_80656A COG:M; EggNog:ENOG410PVDX; InterPro:IPR039367; antiSMASH:Cluster_8.10; go_function: GO:0000009 - alpha-1,6-mannosyltransferase activity [Evidence IEA] AKAW2_80657S COG:S; EggNog:ENOG410PJHA; InterPro:IPR006094,IPR036318,IPR016166,IPR016167, IPR016169; PFAM:PF01565; SMCOG1138:FAD linked oxidase domain protein; antiSMASH:Cluster_8.10; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_function: GO:0071949 - FAD binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_80658A COG:Q; EggNog:ENOG410PFKE; InterPro:IPR009081,IPR036736,IPR036291,IPR020806, IPR013968; PFAM:PF00550,PF08659; antiSMASH:Cluster_8.10; go_function: GO:0031177 - phosphopantetheine binding [Evidence IEA] AKAW2_80659A COG:Q; EggNog:ENOG410PFKE; InterPro:IPR016036,IPR016035,IPR016039,IPR018201, IPR042104,IPR014030,IPR011032,IPR013154,IPR001227, IPR032821,IPR014031,IPR014043,IPR002328,IPR020807, IPR020843,IPR020841,IPR013149,IPR029063,IPR036291; PFAM:PF16197,PF00109,PF02801,PF00698,PF13602, PF14765,PF00107,PF08240; SMCOG1022:Beta-ketoacyl synthase; antiSMASH:Cluster_8.10; go_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein] synthase activity [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0016740 - transferase activity [Evidence IEA]; go_function: GO:0016746 - transferase activity, transferring acyl groups [Evidence IEA]; go_process: GO:0006633 - fatty acid biosynthetic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_80660S COG:S; EggNog:ENOG410PRT3; InterPro:IPR005645,IPR029058; PFAM:PF03959; antiSMASH:Cluster_8.10 AKAW2_80661S InterPro:IPR024311; PFAM:PF13924; antiSMASH:Cluster_8.10 AKAW2_80662S COG:I; EggNog:ENOG410Q2XZ; InterPro:IPR016036,IPR016035,IPR016039,IPR042104, IPR014030,IPR011032,IPR013968,IPR011118,IPR013154, IPR001227,IPR032821,IPR014031,IPR014043,IPR020807, IPR020843,IPR020841,IPR009081,IPR013149,IPR029063, IPR036736,IPR036291,IPR013217; PFAM:PF00109,PF05401,PF00550,PF13489,PF01209, PF08240,PF02801,PF00698,PF13847,PF13649,PF08659,PF14765, PF00107,PF08242,PF08241; SMCOG1022:Beta-ketoacyl synthase; antiSMASH:Cluster_8.10; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0016740 - transferase activity [Evidence IEA]; go_function: GO:0016746 - transferase activity, transferring acyl groups [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_80663A COG:S; EggNog:ENOG410PW0A; InterPro:IPR001810,IPR036047; PFAM:PF00646; antiSMASH:Cluster_8.10; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_80664A COG:S; EggNog:ENOG410PIJ9; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; antiSMASH:Cluster_8.10; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_80665S COG:S; EggNog:ENOG410PJ77; antiSMASH:Cluster_8.10 AKAW2_80666S COG:O; EggNog:ENOG410PFVX; InterPro:IPR019479,IPR000866,IPR036249,IPR013766, IPR024706; PFAM:PF08534,PF10417,PF00578; SMCOG1196:alkyl hydroperoxide reductase/ Thiol specific; antiSMASH:Cluster_8.10; go_function: GO:0016209 - antioxidant activity [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0051920 - peroxiredoxin activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_80667S CAZy:GH5; COG:G; EggNog:ENOG410PJVJ; InterPro:IPR017853,IPR001547; PFAM:PF00150; TransMembrane:1 (i307-327o); antiSMASH:Cluster_8.10; go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_process: GO:0071704 - organic substance metabolic process [Evidence IEA] AKAW2_80668S COG:S; EggNog:ENOG410PWQZ; InterPro:IPR036864,IPR021858,IPR001138; PFAM:PF00172; antiSMASH:Cluster_8.10; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_80669S COG:S; EggNog:ENOG410PWQZ; antiSMASH:Cluster_8.10 AKAW2_80670A BUSCO:EOG09262WSH; COG:K,U; EggNog:ENOG410PKUD; InterPro:IPR012617,IPR039223,IPR025160; PFAM:PF08164,PF13339; antiSMASH:Cluster_8.10; go_component: GO:0005634 - nucleus [Evidence IEA] AKAW2_80671S COG:D; EggNog:ENOG410PJTC; InterPro:IPR019591,IPR027417,IPR033756; PFAM:PF01656,PF10609 AKAW2_80672A COG:V; EggNog:ENOG410PFB2; InterPro:IPR029058,IPR013094; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_80673A COG:L; EggNog:ENOG410PV2R; InterPro:IPR038718,IPR000330,IPR027417,IPR014001; PFAM:PF00176,PF04851; go_function: GO:0005524 - ATP binding [Evidence IEA] AKAW2_80674A COG:S; EggNog:ENOG410Q02V; TransMembrane:2 (i369-388o394-409i) AKAW2_80675S COG:S; EggNog:ENOG410Q1UZ AKAW2_80676S TransMembrane:1 (o306-326i) AKAW2_80677A COG:S; EggNog:ENOG410PYVR; SECRETED:SignalP(1-19) AKAW2_80678S COG:S; EggNog:ENOG410PIG5; InterPro:IPR001810,IPR036047; PFAM:PF00646,PF12937; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_80679S COG:Q; EggNog:ENOG410PJ7N; InterPro:IPR036291,IPR011032,IPR020843,IPR002364; PFAM:PF00107,PF13602; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA] AKAW2_80680A COG:E; EggNog:ENOG410PISA; InterPro:IPR002933,IPR011650,IPR017439,IPR036264; MEROPS:MER0002655; PFAM:PF01546,PF07687; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_80681S COG:Q; EggNog:ENOG410PKKR; InterPro:IPR017871,IPR027417,IPR003593,IPR011527, IPR003439,IPR036640; PFAM:PF00005,PF00664; TransMembrane:14 (o27-47i68-87o93-113i125-147o153-172i266-287o307-328i379- 397o403-424i882-908o928-952i1024-1044o1109-1130i1137- 1160o); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA]; go_function: GO:0042626 - ATPase-coupled transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_80682A COG:S; EggNog:ENOG410PQBQ; InterPro:IPR021833; PFAM:PF11905 AKAW2_80683S COG:M; EggNog:ENOG410PWIM; InterPro:IPR002110,IPR036770,IPR020683,IPR000433; PFAM:PF12796,PF00023,PF13637,PF13606; go_function: GO:0005515 - protein binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA] AKAW2_80684S COG:Q; EggNog:ENOG410PM7A; InterPro:IPR017871,IPR027417,IPR003593,IPR011527, IPR003439,IPR036640; PFAM:PF00005,PF00664; TransMembrane:17 (o24-45i66-85o97-117i129-147o153-173i194-211o265-286i307- 327o401-422i485-512o524-542i875-894o925-947i992-1015o1021- 1041i1105-1126o1132-1151i); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA]; go_function: GO:0042626 - ATPase-coupled transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_80685S COG:T; EggNog:ENOG410PM2Z; InterPro:IPR004813; PFAM:PF03169; TransMembrane:14 (o79-96i108-127o194-217i261-279o346-362i369-391o411- 434i467-486o492-515i576-601o621-638i645-668o695-715i727- 753o); go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_80686A COG:S; EggNog:ENOG410PYHS; TransMembrane:1 (o162-185i) AKAW2_80687S COG:S; EggNog:ENOG410PYW2 AKAW2_80688S COG:J; EggNog:ENOG410PS5A; InterPro:IPR038584,IPR001705,IPR011332; PFAM:PF00471; go_component: GO:0005840 - ribosome [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_process: GO:0006412 - translation [Evidence IEA] AKAW2_80689A COG:S; EggNog:ENOG410PY4D AKAW2_80690S TransMembrane:1 (o92-116i) AKAW2_80691S COG:S; EggNog:ENOG410PV2S; InterPro:IPR004104,IPR000683,IPR036291; PFAM:PF02894,PF01408; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA] AKAW2_80692S COG:S; EggNog:ENOG410PW10; InterPro:IPR033433,IPR008928,IPR032515,IPR032514, IPR014870; PFAM:PF17168,PF16334,PF16335,PF08760; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_80693S COG:S; EggNog:ENOG410PGW9; InterPro:IPR018829; PFAM:PF10360 AKAW2_80694S TransMembrane:2 (n4-14c18/19o90-110i142-160o) AKAW2_80695A COG:K; EggNog:ENOG410PK9J; InterPro:IPR004827,IPR013910,IPR023167; PFAM:PF00170,PF08601; go_function: GO:0003700 - DNA-binding transcription factor activity [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_80696S COG:A; EggNog:ENOG410PH53; InterPro:IPR002999,IPR041297; PFAM:PF18115 AKAW2_80697A COG:S; EggNog:ENOG410PWTZ; TransMembrane:8 (i21-44o64-83i95-119o139-162i174-199o219-241i253-275o287- 312i) AKAW2_80698S COG:Q; EggNog:ENOG410PJFA; InterPro:IPR020946,IPR036188; PFAM:PF13450; go_function: GO:0004499 - N,N-dimethylaniline monooxygenase activity [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_function: GO:0050661 - NADP binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_80699A COG:S; EggNog:ENOG410PJ7E; InterPro:IPR000073,IPR029058; MEROPS:MER0209971; PFAM:PF12697 AKAW2_80700A COG:I; EggNog:ENOG410PW7X; InterPro:IPR006176,IPR008927,IPR006108,IPR036291, IPR000033,IPR011042,IPR013328; PFAM:PF02737,PF00725; go_function: GO:0003857 - 3-hydroxyacyl-CoA dehydrogenase activity [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0006631 - fatty acid metabolic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_80701A COG:T; EggNog:ENOG410PHEY; InterPro:IPR002018,IPR029058; MEROPS:MER0033188; PFAM:PF00135 AKAW2_80702A COG:S; EggNog:ENOG410Q0CK; TransMembrane:4 (o12-30i314-335o350-369i389-414o) AKAW2_80703A COG:S; EggNog:ENOG410PUSY; InterPro:IPR011009,IPR002575; PFAM:PF01636; TransMembrane:1 (i28-47o) AKAW2_80704S COG:T; EggNog:ENOG410PWBG; InterPro:IPR000719,IPR011009; PFAM:PF00069; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_80705A COG:S; EggNog:ENOG410PW69; InterPro:IPR008947,IPR003154; PFAM:PF02265; SECRETED:SignalP(1-19); go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0004519 - endonuclease activity [Evidence IEA]; go_function: GO:0016788 - hydrolase activity, acting on ester bonds [Evidence IEA]; go_process: GO:0006308 - DNA catabolic process [Evidence IEA] AKAW2_80706A COG:S; EggNog:ENOG410Q2BE; InterPro:IPR019268; PFAM:PF10042 AKAW2_80707S COG:S; EggNog:ENOG410PMES; InterPro:IPR029058,IPR018712; PFAM:PF09994 AKAW2_80708S COG:G; EggNog:ENOG410PG9P; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:11 (o44-68i80-104o110-128i140-166o172-191i203-227o247- 268i308-331o337-354i375-395o407-427i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_80709A COG:S; EggNog:ENOG410PMGG; InterPro:IPR011009,IPR002575; PFAM:PF02958,PF01636 AKAW2_80710A COG:S; EggNog:ENOG410PS70; InterPro:IPR002523; PFAM:PF01544; TransMembrane:2 (i163-185o191-213i); go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0046873 - metal ion transmembrane transporter activity [Evidence IEA]; go_process: GO:0030001 - metal ion transport [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_80713A COG:E; EggNog:ENOG410PJD8; InterPro:IPR015424,IPR002129,IPR015421; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0016831 - carboxy-lyase activity [Evidence IEA]; go_function: GO:0030170 - pyridoxal phosphate binding [Evidence IEA]; go_process: GO:0019752 - carboxylic acid metabolic process [Evidence IEA] AKAW2_80714A COG:O; EggNog:ENOG410PRPB; InterPro:IPR010357,IPR036249; PFAM:PF06110 AKAW2_80715A COG:G; EggNog:ENOG410Q235; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:11 (o32-54i75-94o100-122i134-156o162-183i195-214o240-263i275- 296o316-349i370-387o399-422i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_80716A COG:S; EggNog:ENOG410PQ9Y; InterPro:IPR044053; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA] AKAW2_80717A COG:C; EggNog:ENOG410PGTG; InterPro:IPR001155,IPR013785; PFAM:PF00724; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0010181 - FMN binding [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_80718A COG:S; EggNog:ENOG410PX6B; InterPro:IPR010730; PFAM:PF06985 AKAW2_80719A COG:V; EggNog:ENOG410PN7G; InterPro:IPR036291,IPR001509; go_function: GO:0003824 - catalytic activity [Evidence IEA] AKAW2_80720A COG:V; EggNog:ENOG410PN7G; InterPro:IPR036291,IPR001509; PFAM:PF13460,PF01370; TransMembrane:1 (o30-53i); go_function: GO:0003824 - catalytic activity [Evidence IEA] AKAW2_80721S COG:S; EggNog:ENOG410PQAI; InterPro:IPR028116,IPR014347; PFAM:PF14832 AKAW2_80724S COG:K; EggNog:ENOG410PGSE; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_80725A COG:A; EggNog:ENOG410Q1QM; InterPro:IPR041677,IPR027417,IPR041679; PFAM:PF13245,PF13086,PF13087; go_function: GO:0004386 - helicase activity [Evidence IEA] AKAW2_80727S COG:Q; EggNog:ENOG410PJ8H; InterPro:IPR001128,IPR017972,IPR002401,IPR036396; PFAM:PF00067; TransMembrane:1 (n2-13c18/19o290-312i); go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_80728A CAZy:GH28; COG:G; EggNog:ENOG410PHHF; InterPro:IPR000743,IPR012334,IPR011050; PFAM:PF00295; SECRETED:SignalP(1-22); go_function: GO:0004650 - polygalacturonase activity [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_80729S antiSMASH:Cluster_8.11 AKAW2_80730A COG:S; EggNog:ENOG410PYID; InterPro:IPR014710,IPR011051,IPR013096; PFAM:PF07883,PF02311; antiSMASH:Cluster_8.11 AKAW2_80731A antiSMASH:Cluster_8.11 AKAW2_80732A COG:S; EggNog:ENOG410PVT2; antiSMASH:Cluster_8.11 AKAW2_80733S COG:S; EggNog:ENOG410Q2BE; InterPro:IPR019268; PFAM:PF10042; antiSMASH:Cluster_8.11 AKAW2_80734S COG:Q; EggNog:ENOG410PUDN; InterPro:IPR001128,IPR002403,IPR017972,IPR036396; PFAM:PF00067; SMCOG1034:cytochrome P450; TransMembrane:1 (i12-33o); antiSMASH:Cluster_8.11; go_function: GO:0004497 - monooxygenase activity [Evidence IEA]; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_80735S COG:E; EggNog:ENOG410PW6R; InterPro:IPR002293; PFAM:PF00324,PF13520; SMCOG1038:phenylalanine-specific permease; TransMembrane:10 (i42-62o74-96i124-143o163-182i194-214o269-291i371-390o396- 417i437-454o466-485i); antiSMASH:Cluster_8.11; go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_80736A COG:Q; EggNog:ENOG410PM3X; InterPro:IPR036291,IPR002347; PFAM:PF08659,PF00106,PF13561; SMCOG1001:short-chain dehydrogenase/reductase SDR; antiSMASH:Cluster_8.11; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_80737S COG:Q; EggNog:ENOG410PW5J; InterPro:IPR016036,IPR016035,IPR016039,IPR018201, IPR042104,IPR014030,IPR011032,IPR013968,IPR013154, IPR001227,IPR032821,IPR014031,IPR014043,IPR020806, IPR020807,IPR020843,IPR020841,IPR009081,IPR013149, IPR036736,IPR036291; PFAM:PF16197,PF08659,PF00550,PF02801,PF00698, PF13602,PF14765,PF00107,PF00109,PF08240; SMCOG1022:Beta-ketoacyl synthase; antiSMASH:Cluster_8.11; go_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein] synthase activity [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0016740 - transferase activity [Evidence IEA]; go_function: GO:0016746 - transferase activity, transferring acyl groups [Evidence IEA]; go_function: GO:0031177 - phosphopantetheine binding [Evidence IEA]; go_process: GO:0006633 - fatty acid biosynthetic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_80738S COG:Q; EggNog:ENOG410PW5J; InterPro:IPR001242; SECRETED:SignalP(1-35); antiSMASH:Cluster_8.11; go_function: GO:0003824 - catalytic activity [Evidence IEA] AKAW2_80739A COG:S; EggNog:ENOG410PRK7; InterPro:IPR007219; PFAM:PF04082; TransMembrane:1 (o374-394i); antiSMASH:Cluster_8.11; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA] AKAW2_80740S COG:S; EggNog:ENOG410PWQ5; InterPro:IPR036378,IPR000782; PFAM:PF02469; SECRETED:SignalP(1-20); antiSMASH:Cluster_8.11 AKAW2_80741A COG:S; EggNog:ENOG410PQYR; TransMembrane:1 (i20-38o); antiSMASH:Cluster_8.11 AKAW2_80742A antiSMASH:Cluster_8.11 AKAW2_80743S COG:S; EggNog:ENOG410PX04; SECRETED:SignalP(1-25); TransMembrane:4 (n10-20c25/26o54-74i258-277o283-305i449-470o); antiSMASH:Cluster_8.11 AKAW2_80744S COG:S; EggNog:ENOG410PX04; TransMembrane:2 (i99-118o124-145i); antiSMASH:Cluster_8.11 AKAW2_80745A COG:G; EggNog:ENOG410QDJA; InterPro:IPR011701,IPR036259; PFAM:PF07690; TransMembrane:10 (i94-113o119-140i147-168o180-198i210-229o335-352i364- 381o393-412i424-445o457-478i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_80746A COG:G; EggNog:ENOG410QDYM; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:10 (i142-160o166-188i200-221o227-248i305-324o344-366i387- 407o413-432i444-465o485-506i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_80747S COG:O; EggNog:ENOG410PSVP; InterPro:IPR036249,IPR040079,IPR034345,IPR036282, IPR010987,IPR004045,IPR004046; PFAM:PF13409,PF00043,PF13417,PF13410,PF02798; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0006749 - glutathione metabolic process [Evidence IEA] AKAW2_80748S SECRETED:SignalP(1-21) AKAW2_80749A COG:I; EggNog:ENOG410PVGT; InterPro:IPR002656; PFAM:PF01757; TransMembrane:9 (o54-73i101-122o142-159i171-194o206-228i240-258o294- 311i323-342o371-395i); go_function: GO:0016747 - transferase activity, transferring acyl groups other than amino-acyl groups [Evidence IEA] AKAW2_80750A CAZy:GT2_Glyco_trans_2; COG:S; EggNog:ENOG410PRDY; InterPro:IPR001173,IPR029044,IPR027389; PFAM:PF13632; TransMembrane:3 (o32-54i337-362o406-429i); go_function: GO:0019187 - beta-1,4-mannosyltransferase activity [Evidence IEA] AKAW2_80751A COG:G; EggNog:ENOG410Q07H; InterPro:IPR036259; TransMembrane:3 (o23-50i62-85o91-113i) AKAW2_80752S COG:K; EggNog:ENOG410PM5K; InterPro:IPR012349,IPR007396; PFAM:PF04299 AKAW2_80753A COG:Q; EggNog:ENOG410PUIW; InterPro:IPR001128,IPR017972,IPR002401,IPR036396; PFAM:PF00067; TransMembrane:2 (o6-25i37-56o); go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_80754S COG:I; EggNog:ENOG410PMS4; InterPro:IPR013830,IPR036514; PFAM:PF00657,PF13472 AKAW2_80755S COG:F,P; EggNog:ENOG410PG6B; InterPro:IPR005829,IPR005828,IPR003663,IPR036259, IPR020846; PFAM:PF00083,PF07690; TransMembrane:12 (i40-69o84-104i111-131o137-159i171-193o199-220i287- 307o327-348i360-380o392-412i433-453o465-483i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_80756S COG:S; EggNog:ENOG410PN8G; InterPro:IPR021858 AKAW2_80757A COG:S; EggNog:ENOG410PGJF; InterPro:IPR006620,IPR005123; PFAM:PF13640; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0031418 - L-ascorbic acid binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_80758A BUSCO:EOG09265DAV; COG:J; EggNog:ENOG410PPNW; InterPro:IPR005756,IPR041988,IPR008991,IPR005825, IPR005824,IPR014722; PFAM:PF00467,PF16906; go_component: GO:0005840 - ribosome [Evidence IEA]; go_component: GO:0015934 - large ribosomal subunit [Evidence IEA]; go_function: GO:0003723 - RNA binding [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_process: GO:0006412 - translation [Evidence IEA] AKAW2_80759A COG:U; EggNog:ENOG410QDY7; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i163-183o203-222i234-260o266-286i293-313o333-351i394- 417o437-457i478-497o503-530i550-567o573-593i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_80760S COG:G; EggNog:ENOG410Q07H; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i80-99o111-135i147-166o172-195i207-228o234-252i311- 337o349-370i391-413o425-446i453-475o487-507i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_80761S COG:S; EggNog:ENOG410PX2U; InterPro:IPR001138,IPR036864; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_80762A COG:O; EggNog:ENOG410Q2WU; InterPro:IPR033121,IPR021109,IPR001461; MEROPS:MER0000931; PFAM:PF00026; SECRETED:SignalP(1-20); go_function: GO:0004190 - aspartic-type endopeptidase activity [Evidence IEA]; go_process: GO:0006508 - proteolysis [Evidence IEA] AKAW2_80763S COG:S; EggNog:ENOG410PPFN; InterPro:IPR010730; PFAM:PF06985 AKAW2_80764A COG:S; EggNog:ENOG410PHE9; PFAM:PF13668; SECRETED:SignalP(1-18) AKAW2_80765A COG:S; EggNog:ENOG410PVNH; InterPro:IPR036864,IPR021858,IPR001138; PFAM:PF00172; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_80766S COG:S; EggNog:ENOG410PWHC; InterPro:IPR011009 AKAW2_80767S COG:S; EggNog:ENOG410PWHC AKAW2_80768A COG:S; EggNog:ENOG410PY4S AKAW2_80769A COG:S; EggNog:ENOG410PPD0; InterPro:IPR006674,IPR017771,IPR003607; PFAM:PF01966 AKAW2_80770A COG:S; EggNog:ENOG410PNRX; InterPro:IPR033121,IPR021109; TransMembrane:1 (o179-203i) AKAW2_80771S COG:Q; EggNog:ENOG410PM84; InterPro:IPR001128,IPR036396; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_80772A COG:E; EggNog:ENOG410PIS1; InterPro:IPR020558,IPR000581,IPR037237,IPR042096; PFAM:PF00920; go_function: GO:0003824 - catalytic activity [Evidence IEA] AKAW2_80773S COG:G; EggNog:ENOG410PKV4; InterPro:IPR005829,IPR005828,IPR003663,IPR036259, IPR020846; PFAM:PF00083,PF07690; TransMembrane:12 (i9-27o67-87i96-117o123-142i154-173o185-206i270-292o312- 333i340-362o368-395i407-426o438-457i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_80774A COG:G; EggNog:ENOG410PM67; InterPro:IPR011042,IPR005511,IPR013658; PFAM:PF08450 AKAW2_80775A COG:S; EggNog:ENOG410PMVN; InterPro:IPR029063; PFAM:PF13489 AKAW2_80776A COG:M; EggNog:ENOG410Q4IV; InterPro:IPR027417,IPR020683,IPR036770 AKAW2_80777A COG:P; EggNog:ENOG410PIFK; InterPro:IPR004837; PFAM:PF01699; TransMembrane:11 (i168-186o192-212i224-246o252-276i288-312o324-342i406- 426o446-468i475-503o509-530i537-557o); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_80778S CAZy:CBM43; CAZy:GH72; COG:S; EggNog:ENOG410PFK7; InterPro:IPR012946,IPR017853,IPR004886; PFAM:PF07983,PF03198; SECRETED:SignalP(1-20) AKAW2_80779S COG:G; EggNog:ENOG410PMGQ; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i52-69o89-109i121-139o145-166i178-202o208-228i269- 293o313-334i355-376o382-405i426-444o450-469i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_80780A COG:K; EggNog:ENOG410PQ7B; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_80782S COG:K; EggNog:ENOG410Q2BJ; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; TransMembrane:1 (o695-713i); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_80783S BUSCO:EOG092604I8; COG:T; EggNog:ENOG410PI1E; InterPro:IPR036388,IPR036390,IPR000591,IPR027244; PFAM:PF00610,PF12257; go_function: GO:0005096 - GTPase activator activity [Evidence IEA]; go_process: GO:0035556 - intracellular signal transduction [Evidence IEA] AKAW2_80784A COG:S; EggNog:ENOG410PIG9; InterPro:IPR028084; PFAM:PF14636 AKAW2_80785A BUSCO:EOG09261FAX; COG:F; EggNog:ENOG410PGQE; InterPro:IPR039754,IPR012580; PFAM:PF08159; go_component: GO:0005634 - nucleus [Evidence IEA]; go_process: GO:0006364 - rRNA processing [Evidence IEA] AKAW2_80786S BUSCO:EOG09264JK1; COG:Z; EggNog:ENOG410PGTF; InterPro:IPR024964,IPR006594,IPR006595,IPR013144; PFAM:PF10607,PF08513; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_80787A COG:S; EggNog:ENOG410PW65; InterPro:IPR010839 AKAW2_80788A COG:S; EggNog:ENOG410PJDF; InterPro:IPR010839; PFAM:PF07287 AKAW2_80789A COG:S; EggNog:ENOG410PP65; InterPro:IPR036412,IPR041492,IPR023214; PFAM:PF13419 AKAW2_80790S COG:Q; EggNog:ENOG410PPGR; InterPro:IPR026992,IPR027443,IPR005123; PFAM:PF03171,PF14226; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_80791A SECRETED:SignalP(1-18) AKAW2_80792A COG:C; EggNog:ENOG410PHXJ; InterPro:IPR036188,IPR011992,IPR002048,IPR018247, IPR023753; PFAM:PF07992,PF00070; TransMembrane:1 (i90-111o); go_function: GO:0005509 - calcium ion binding [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_80793A BUSCO:EOG092604A0; COG:D; EggNog:ENOG410PHGB; InterPro:IPR016024,IPR011989,IPR024986,IPR033031, IPR026003; PFAM:PF12830,PF12765; go_function: GO:0003682 - chromatin binding [Evidence IEA]; go_process: GO:0010468 - regulation of gene expression [Evidence IEA] AKAW2_80794S COG:K; EggNog:ENOG410PNWW; InterPro:IPR019761,IPR034004,IPR012164,IPR001222; PFAM:PF01096; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006379 - mRNA cleavage [Evidence IEA] AKAW2_80795A BUSCO:EOG09263JZO; COG:C; EggNog:ENOG410PJAQ; InterPro:IPR016024,IPR011989,IPR021133,IPR027517, IPR004155; PFAM:PF13646,PF03130; go_function: GO:0019135 - deoxyhypusine monooxygenase activity [Evidence IEA]; go_process: GO:0008612 - peptidyl-lysine modification to peptidyl-hypusine [Evidence IEA] AKAW2_80796A COG:C; EggNog:ENOG410PMWV; InterPro:IPR038532,IPR006885; PFAM:PF04800; go_function: GO:0016651 - oxidoreductase activity, acting on NAD(P)H [Evidence IEA]; go_process: GO:0022900 - electron transport chain [Evidence IEA] AKAW2_80797S BUSCO:EOG09265FTN; COG:C; EggNog:ENOG410PPTD; InterPro:IPR019727; PFAM:PF10791; TransMembrane:1 (o73-91i); go_component: GO:0000276 - mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) [Evidence IEA]; go_process: GO:0015986 - ATP synthesis coupled proton transport [Evidence IEA] AKAW2_80798A COG:S; EggNog:ENOG410PU0E AKAW2_80799S COG:S; EggNog:ENOG410Q2MM AKAW2_80800S COG:S; EggNog:ENOG410QE28; InterPro:IPR013087 AKAW2_80801S COG:S; EggNog:ENOG410QDP4; InterPro:IPR015943,IPR001680,IPR036322,IPR017986; PFAM:PF00400; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_80802S COG:S; EggNog:ENOG410PP6N; InterPro:IPR034771,IPR035979,IPR012677,IPR034772; go_function: GO:0003676 - nucleic acid binding [Evidence IEA] AKAW2_80803S COG:U; EggNog:ENOG410PNAS; InterPro:IPR042138,IPR001683,IPR036871; PFAM:PF00787; go_function: GO:0032266 - phosphatidylinositol-3-phosphate binding [Evidence IEA]; go_function: GO:0035091 - phosphatidylinositol binding [Evidence IEA] AKAW2_80804A COG:K; EggNog:ENOG410PGHY; InterPro:IPR001005,IPR009057,IPR017877; PFAM:PF00249,PF13921 AKAW2_80805S COG:S; EggNog:ENOG410PPPJ; TransMembrane:3 (o58-77i89-109o129-149i) AKAW2_80806A COG:S; EggNog:ENOG410PU94; InterPro:IPR036964,IPR023578; go_function: GO:0005085 - guanyl-nucleotide exchange factor activity [Evidence IEA]; go_process: GO:0007264 - small GTPase mediated signal transduction [Evidence IEA] AKAW2_80807A COG:J; EggNog:ENOG410PFCX; InterPro:IPR041982,IPR032277,IPR038237,IPR000876, IPR002942,IPR018199,IPR013843,IPR013845,IPR014722; PFAM:PF00900,PF08071,PF01479,PF16121; go_component: GO:0005840 - ribosome [Evidence IEA]; go_function: GO:0003723 - RNA binding [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_process: GO:0006412 - translation [Evidence IEA] AKAW2_80808A BUSCO:EOG09262YAU; COG:E; EggNog:ENOG410PHPF; InterPro:IPR036291,IPR012280,IPR000534,IPR005676; PFAM:PF02774,PF01118; go_function: GO:0016620 - oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Evidence IEA]; go_function: GO:0046983 - protein dimerization activity [Evidence IEA]; go_function: GO:0050661 - NADP binding [Evidence IEA]; go_function: GO:0051287 - NAD binding [Evidence IEA]; go_process: GO:0008652 - cellular amino acid biosynthetic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_80809A CAZy:AA4; COG:C; EggNog:ENOG410PGHW; InterPro:IPR016171,IPR006094,IPR036318,IPR004113, IPR016164,IPR016166,IPR016167,IPR016169; PFAM:PF02913,PF01565; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_function: GO:0071949 - FAD binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_80810S COG:S; EggNog:ENOG410PU4R AKAW2_80811S COG:A; EggNog:ENOG410PFI8; InterPro:IPR007855; PFAM:PF05183; go_function: GO:0003968 - RNA-directed 5'-3' RNA polymerase activity [Evidence IEA] AKAW2_80812A BUSCO:EOG092602FH; COG:L; EggNog:ENOG410PFY9; InterPro:IPR043502,IPR025687,IPR036397,IPR012337, IPR030559,IPR017964,IPR042087,IPR006133,IPR006172, IPR023211,IPR006134; PFAM:PF14260,PF00136; go_component: GO:0016035 - zeta DNA polymerase complex [Evidence IEA]; go_function: GO:0000166 - nucleotide binding [Evidence IEA]; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0003887 - DNA-directed DNA polymerase activity [Evidence IEA]; go_process: GO:0006281 - DNA repair [Evidence IEA]; go_process: GO:0019985 - translesion synthesis [Evidence IEA] AKAW2_80813S BUSCO:EOG09262NNS; COG:A; EggNog:ENOG410PI74; InterPro:IPR021715,IPR039974; PFAM:PF11708; go_function: GO:0000386 - second spliceosomal transesterification activity [Evidence IEA]; go_function: GO:0030628 - pre-mRNA 3'-splice site binding [Evidence IEA]; go_process: GO:0000398 - mRNA splicing, via spliceosome [Evidence IEA] AKAW2_80814S COG:J; EggNog:ENOG410PQSM; InterPro:IPR001569,IPR018267,IPR011331,IPR011332; PFAM:PF01907; go_component: GO:0005840 - ribosome [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_process: GO:0006412 - translation [Evidence IEA] AKAW2_80815A COG:S; EggNog:ENOG410PTMH; InterPro:IPR018627; TransMembrane:1 (o20-39i); go_component: GO:0033588 - Elongator holoenzyme complex [Evidence IEA]; go_process: GO:0002098 - tRNA wobble uridine modification [Evidence IEA] AKAW2_80816S COG:K; EggNog:ENOG410PIUD; InterPro:IPR036864,IPR007219,IPR005600,IPR001138; PFAM:PF00172,PF04082; TransMembrane:1 (o543-563i); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_80817A COG:G; EggNog:ENOG410PI4Z; InterPro:IPR005829,IPR005828,IPR003663,IPR036259, IPR020846; PFAM:PF00083,PF07690; TransMembrane:11 (o75-93i105-127o133-152i164-182o234-251i332-354o374- 391i398-421o433-458i470-489o501-520i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_80818A COG:O; EggNog:ENOG410PI7S; InterPro:IPR042467,IPR003323,IPR042468,IPR019400, IPR038765; MEROPS:MER0029056; PFAM:PF10275 AKAW2_80820A COG:O,T; EggNog:ENOG410PG16; InterPro:IPR036390,IPR037750,IPR000717; PFAM:PF01399; go_component: GO:0008180 - COP9 signalosome [Evidence IEA] AKAW2_80821S BUSCO:EOG09264YNR; COG:S; EggNog:ENOG410PFG4; InterPro:IPR005225,IPR001806,IPR027417,IPR003578; PFAM:PF00025,PF08477,PF00071; go_function: GO:0003924 - GTPase activity [Evidence IEA]; go_function: GO:0005525 - GTP binding [Evidence IEA]; go_process: GO:0007264 - small GTPase mediated signal transduction [Evidence IEA] AKAW2_80822A BUSCO:EOG09264AWW; COG:H; EggNog:ENOG410PPYW; InterPro:IPR020605,IPR004143,IPR000544; antiSMASH:Cluster_8.12; go_function: GO:0033819 - lipoyl(octanoyl) transferase activity [Evidence IEA]; go_process: GO:0006464 - cellular protein modification process [Evidence IEA]; go_process: GO:0009249 - protein lipoylation [Evidence IEA] AKAW2_80823A COG:S; EggNog:ENOG410PNI4; InterPro:IPR011576; PFAM:PF01243; antiSMASH:Cluster_8.12 AKAW2_80824S COG:S; EggNog:ENOG410PJ4C; InterPro:IPR011008,IPR012577; PFAM:PF07978; antiSMASH:Cluster_8.12 AKAW2_80825S COG:I; EggNog:ENOG410PGVP; InterPro:IPR014472,IPR000462,IPR043130; PFAM:PF01066; TransMembrane:9 (i50-69o81-101i122-143o163-193i228-250o262-281i293- 314o320-342i354-371o); antiSMASH:Cluster_8.12; go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0016780 - phosphotransferase activity, for other substituted phosphate groups [Evidence IEA]; go_process: GO:0008654 - phospholipid biosynthetic process [Evidence IEA] AKAW2_80826S COG:J; EggNog:ENOG410Q169; InterPro:IPR000592,IPR011332; PFAM:PF01667; antiSMASH:Cluster_8.12; go_component: GO:0005840 - ribosome [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_process: GO:0006412 - translation [Evidence IEA] AKAW2_80827S antiSMASH:Cluster_8.12 AKAW2_80828S COG:E; EggNog:ENOG410PPSZ; InterPro:IPR005645,IPR029058; PFAM:PF03959; antiSMASH:Cluster_8.12 AKAW2_80829A BUSCO:EOG09262P1W; COG:O; EggNog:ENOG410PIGS; InterPro:IPR036388,IPR040134,IPR036390,IPR040896, IPR035297,IPR000717; PFAM:PF18098,PF01399; antiSMASH:Cluster_8.12 AKAW2_80830S COG:H; EggNog:ENOG410PF8D; InterPro:IPR006366,IPR012066,IPR035996,IPR014776, IPR014777,IPR000878,IPR028162,IPR036291,IPR003043, IPR028281; PFAM:PF14824,PF13241,PF14823,PF00590; antiSMASH:Cluster_8.12; go_function: GO:0004851 - uroporphyrin-III C-methyltransferase activity [Evidence IEA]; go_function: GO:0008168 - methyltransferase activity [Evidence IEA]; go_process: GO:0000103 - sulfate assimilation [Evidence IEA]; go_process: GO:0019354 - siroheme biosynthetic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_80831A COG:I; EggNog:ENOG410Q1IU; InterPro:IPR042099,IPR000873,IPR020845; PFAM:PF00501; SMCOG1002:AMP-dependent synthetase and ligase; antiSMASH:Cluster_8.12 AKAW2_80832S COG:I; EggNog:ENOG410PIJA; InterPro:IPR016036,IPR016035,IPR016039,IPR018201, IPR042104,IPR014030,IPR014031,IPR013968,IPR001227, IPR032821,IPR006162,IPR014043,IPR020806,IPR020807, IPR020841,IPR009081,IPR029063,IPR036736,IPR036291, IPR013217; PFAM:PF16197,PF00109,PF00550,PF13649,PF02801, PF00698,PF08659,PF14765,PF00106,PF08242,PF08241; SMCOG1022:Beta-ketoacyl synthase; antiSMASH:Cluster_8.12; go_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein] synthase activity [Evidence IEA]; go_function: GO:0016740 - transferase activity [Evidence IEA]; go_function: GO:0016746 - transferase activity, transferring acyl groups [Evidence IEA]; go_function: GO:0031177 - phosphopantetheine binding [Evidence IEA]; go_process: GO:0006633 - fatty acid biosynthetic process [Evidence IEA] AKAW2_80833S COG:O; EggNog:ENOG410PZTW; TransMembrane:1 (o81-102i); antiSMASH:Cluster_8.12 AKAW2_80834S COG:F; EggNog:ENOG410PQA3; InterPro:IPR011343,IPR028581,IPR002915,IPR013785; PFAM:PF01791; antiSMASH:Cluster_8.12; go_component: GO:0005737 - cytoplasm [Evidence IEA]; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0004139 - deoxyribose-phosphate aldolase activity [Evidence IEA]; go_function: GO:0016829 - lyase activity [Evidence IEA]; go_process: GO:0009264 - deoxyribonucleotide catabolic process [Evidence IEA] AKAW2_80835S COG:L; EggNog:ENOG410PGU9; InterPro:IPR029028,IPR003750,IPR029026; PFAM:PF02598; antiSMASH:Cluster_8.12 AKAW2_80836A COG:S; EggNog:ENOG410PKTI; InterPro:IPR015943,IPR001680,IPR036322,IPR017986; PFAM:PF00400; SMCOG1173:WD-40 repeat-containing protein; antiSMASH:Cluster_8.12; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_80837S COG:S; EggNog:ENOG410PYYU; antiSMASH:Cluster_8.12 AKAW2_80838S COG:T; EggNog:ENOG410PW4Q; InterPro:IPR000719,IPR011009,IPR017441; PFAM:PF00069; SMCOG1030:serine/threonine protein kinase; antiSMASH:Cluster_8.12; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_80839S BUSCO:EOG0926131E; COG:H; EggNog:ENOG410PI7C; InterPro:IPR031691,IPR006638,IPR007197,IPR003698, IPR013785; PFAM:PF04055,PF16881; antiSMASH:Cluster_8.12; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0016992 - lipoate synthase activity [Evidence IEA]; go_function: GO:0051536 - iron-sulfur cluster binding [Evidence IEA]; go_function: GO:0051539 - 4 iron, 4 sulfur cluster binding [Evidence IEA]; go_process: GO:0009107 - lipoate biosynthetic process [Evidence IEA] AKAW2_80840A COG:E; EggNog:ENOG410PMA2; InterPro:IPR036412,IPR023214; PFAM:PF00702,PF12710,PF06888; antiSMASH:Cluster_8.12 AKAW2_80841S BUSCO:EOG09264FVQ; COG:E; EggNog:ENOG410PI92; InterPro:IPR002500,IPR011800,IPR004511,IPR014729; PFAM:PF01507; antiSMASH:Cluster_8.12; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0004604 - phosphoadenylyl-sulfate reductase (thioredoxin) activity [Evidence IEA]; go_process: GO:0019379 - sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_80842S COG:P; EggNog:ENOG410PFXE; InterPro:IPR027417,IPR025980,IPR024951,IPR002650, IPR015947,IPR014729,IPR027535,IPR002891; PFAM:PF01583,PF14306,PF01747; go_function: GO:0004020 - adenylylsulfate kinase activity [Evidence IEA]; go_function: GO:0004781 - sulfate adenylyltransferase (ATP) activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0000096 - sulfur amino acid metabolic process [Evidence IEA]; go_process: GO:0000103 - sulfate assimilation [Evidence IEA] AKAW2_80843S COG:S; EggNog:ENOG410PI2K; TransMembrane:1 (i96-115o) AKAW2_80844A COG:S; EggNog:ENOG410PNCU; InterPro:IPR000742; TransMembrane:1 (o535-561i) AKAW2_80845A COG:S; EggNog:ENOG410PS2Q; InterPro:IPR040357; go_process: GO:0070072 - vacuolar proton-transporting V-type ATPase complex assembly [Evidence IEA] AKAW2_80846S COG:A; EggNog:ENOG410PPKQ; InterPro:IPR008011; PFAM:PF13233,PF05347 AKAW2_80847S COG:S; EggNog:ENOG410PPDI AKAW2_80848A COG:K; EggNog:ENOG410PHWP; InterPro:IPR006560,IPR003616,IPR001214; PFAM:PF17907,PF00856; go_component: GO:0005634 - nucleus [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_function: GO:0018024 - histone-lysine N-methyltransferase activity [Evidence IEA] AKAW2_80849A BUSCO:EOG09264FYY; COG:S; EggNog:ENOG410PGMU; InterPro:IPR001594; PFAM:PF01529; TransMembrane:4 (i322-341o353-375i468-493o513-535i); go_function: GO:0016409 - palmitoyltransferase activity [Evidence IEA] AKAW2_80851S COG:S; EggNog:ENOG410PQWI; InterPro:IPR039965; TransMembrane:1 (i46-65o) AKAW2_80850A CAZy:GT39; COG:O; EggNog:ENOG410PFPS; InterPro:IPR036300,IPR027005,IPR016093,IPR003342, IPR027004,IPR032421; PFAM:PF16192,PF02815,PF02366; TransMembrane:11 (i106-124o144-166i173-190o196-216i228-245o251-271i291- 311o614-635i656-673o685-702i714-734o); go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0000030 - mannosyltransferase activity [Evidence IEA]; go_function: GO:0004169 - dolichyl-phosphate-mannose-protein mannosyltransferase activity [Evidence IEA]; go_process: GO:0006493 - protein O-linked glycosylation [Evidence IEA] AKAW2_80852S BUSCO:EOG09264RIE; COG:A; EggNog:ENOG410PG4Z; InterPro:IPR035967,IPR022030,IPR000061; PFAM:PF01805,PF12230; go_function: GO:0003723 - RNA binding [Evidence IEA]; go_process: GO:0006396 - RNA processing [Evidence IEA] AKAW2_80853A COG:U; EggNog:ENOG410PJPE; InterPro:IPR040351,IPR009449; PFAM:PF06428; go_function: GO:0005085 - guanyl-nucleotide exchange factor activity [Evidence IEA] AKAW2_80855S BUSCO:EOG09265HEP; COG:D; EggNog:ENOG410PRK4; InterPro:IPR002836,IPR036883; PFAM:PF01984; go_function: GO:0003677 - DNA binding [Evidence IEA] AKAW2_80854A BUSCO:EOG092643VB; COG:H; EggNog:ENOG410PGMW; InterPro:IPR007715,IPR027540; PFAM:PF05019; go_component: GO:0005743 - mitochondrial inner membrane [Evidence IEA]; go_process: GO:0006744 - ubiquinone biosynthetic process [Evidence IEA] AKAW2_80856S COG:S; EggNog:ENOG410PKW5; InterPro:IPR001214; PFAM:PF00856; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_80857A COG:H; EggNog:ENOG410PMYW; InterPro:IPR003710,IPR013752,IPR036291,IPR013332, IPR008927,IPR013328; PFAM:PF02558,PF08546; go_function: GO:0008677 - 2-dehydropantoate 2-reductase activity [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0015940 - pantothenate biosynthetic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_80858S COG:A; EggNog:ENOG410PR5T; InterPro:IPR011082,IPR007146; PFAM:PF04000 AKAW2_80859S BUSCO:EOG09265RGS; COG:S; EggNog:ENOG410PQKG; InterPro:IPR009069 AKAW2_80860A COG:O; EggNog:ENOG410PNS0; InterPro:IPR029071,IPR001012,IPR036249; PFAM:PF00789; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_80862S BUSCO:EOG09263V60; COG:C; EggNog:ENOG410PJEJ; InterPro:IPR002994; PFAM:PF02104; TransMembrane:2 (i90-108o300-319i); go_component: GO:0016020 - membrane [Evidence IEA] AKAW2_80861A COG:S; EggNog:ENOG410PRI1; InterPro:IPR009072,IPR035425; PFAM:PF15630,PF15511; go_function: GO:0046982 - protein heterodimerization activity [Evidence IEA] AKAW2_80863S BUSCO:EOG09264KTU; COG:S; EggNog:ENOG410PMXA; InterPro:IPR032704; PFAM:PF14617 AKAW2_80865S BUSCO:EOG09265DRM; COG:S; EggNog:ENOG410QDTF; InterPro:IPR000504,IPR012677,IPR035979; PFAM:PF00076; go_function: GO:0003676 - nucleic acid binding [Evidence IEA] AKAW2_80866A COG:S; EggNog:ENOG410PIRJ; InterPro:IPR005225,IPR001806,IPR027417,IPR003578; PFAM:PF00025,PF08477,PF00071; go_function: GO:0003924 - GTPase activity [Evidence IEA]; go_function: GO:0005525 - GTP binding [Evidence IEA]; go_process: GO:0007264 - small GTPase mediated signal transduction [Evidence IEA] AKAW2_80867A COG:K; EggNog:ENOG410Q2P8; InterPro:IPR001138,IPR036864; PFAM:PF00172; TransMembrane:1 (o512-528i); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_80868S BUSCO:EOG092620CR; COG:T; EggNog:ENOG410QDQC; InterPro:IPR001060,IPR027267,IPR008936,IPR000198, IPR031160; PFAM:PF00611,PF00620; go_process: GO:0007165 - signal transduction [Evidence IEA] AKAW2_80869A COG:S; EggNog:ENOG410PQM4 AKAW2_80870S COG:S; EggNog:ENOG410PNUC; InterPro:IPR021100; TransMembrane:5 (o6-23i30-50o62-78i90-109o121-139i); go_component: GO:0005789 - endoplasmic reticulum membrane [Evidence IEA]; go_process: GO:0034599 - cellular response to oxidative stress [Evidence IEA] AKAW2_80871A COG:J; EggNog:ENOG410PNPS; InterPro:IPR001950,IPR005874,IPR036877; PFAM:PF01253; go_function: GO:0003743 - translation initiation factor activity [Evidence IEA]; go_process: GO:0006413 - translational initiation [Evidence IEA] AKAW2_80872A COG:S; EggNog:ENOG410PPRR; InterPro:IPR005351; PFAM:PF03669; TransMembrane:2 (i47-63o75-95i) AKAW2_80873S TransMembrane:2 (i75-99o111-133i) AKAW2_80874S BUSCO:EOG092605ZA; COG:K; EggNog:ENOG410PK8U; InterPro:IPR019035; PFAM:PF09497; TransMembrane:2 (o419-446i1016-1035o); go_component: GO:0016592 - mediator complex [Evidence IEA]; go_function: GO:0003712 - transcription coregulator activity [Evidence IEA]; go_process: GO:0006357 - regulation of transcription by RNA polymerase II [Evidence IEA] AKAW2_80875A COG:S; EggNog:ENOG410PIMT; InterPro:IPR000504,IPR012677,IPR035979; PFAM:PF00076; go_function: GO:0003676 - nucleic acid binding [Evidence IEA] AKAW2_80876S COG:S; EggNog:ENOG410PGSM; InterPro:IPR013857,IPR039131,IPR008979; PFAM:PF08547; go_process: GO:0032981 - mitochondrial respiratory chain complex I assembly [Evidence IEA] AKAW2_80877A BUSCO:EOG09260LS9; COG:F; EggNog:ENOG410PFD3; InterPro:IPR001636,IPR018236,IPR028923; PFAM:PF01259; go_function: GO:0004639 - phosphoribosylaminoimidazolesuccinocarboxamide synthase activity [Evidence IEA]; go_process: GO:0006164 - purine nucleotide biosynthetic process [Evidence IEA] AKAW2_80878A COG:S; EggNog:ENOG410PWEN; InterPro:IPR003607 AKAW2_80879S CAZy:GT8; COG:G; EggNog:ENOG410PIS8; InterPro:IPR029044,IPR030518; go_component: GO:0005794 - Golgi apparatus [Evidence IEA]; go_function: GO:0008375 - acetylglucosaminyltransferase activity [Evidence IEA]; go_process: GO:0006487 - protein N-linked glycosylation [Evidence IEA] AKAW2_80880S COG:D; EggNog:ENOG410PHQY; InterPro:IPR026000,IPR037679,IPR011990; PFAM:PF12862; SECRETED:SignalP(1-22); go_component: GO:0005680 - anaphase-promoting complex [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_80881A BUSCO:EOG092654RM; COG:C; EggNog:ENOG410PNPT; InterPro:IPR001349,IPR036418,IPR018507; PFAM:PF02046; TransMembrane:1 (i68-88o); go_component: GO:0005743 - mitochondrial inner membrane [Evidence IEA]; go_component: GO:0005751 - mitochondrial respiratory chain complex IV [Evidence IEA]; go_function: GO:0004129 - cytochrome-c oxidase activity [Evidence IEA] AKAW2_80882S COG:L; EggNog:ENOG410PJN6; InterPro:IPR020848,IPR004808,IPR036691,IPR005135; PFAM:PF03372; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0004518 - nuclease activity [Evidence IEA]; go_function: GO:0004519 - endonuclease activity [Evidence IEA]; go_process: GO:0006281 - DNA repair [Evidence IEA] AKAW2_80883A COG:K; EggNog:ENOG410QDNT; InterPro:IPR009071,IPR036910; PFAM:PF00505,PF09011 AKAW2_80884S COG:S; EggNog:ENOG410PYBK AKAW2_80885S COG:S; EggNog:ENOG410PSJS; InterPro:IPR015943,IPR001680,IPR036322,IPR017986; PFAM:PF00400; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_80886A COG:C; EggNog:ENOG410PIWP; InterPro:IPR015590,IPR029510,IPR016161,IPR016162, IPR016163; PFAM:PF00171; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0016620 - oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_80887S COG:I; EggNog:ENOG410PG69; InterPro:IPR023606,IPR003673; PFAM:PF02515; go_function: GO:0008410 - CoA-transferase activity [Evidence IEA] AKAW2_80888S COG:C,H; EggNog:ENOG410PUCM; InterPro:IPR036188 AKAW2_80889A BUSCO:EOG09261A3K; COG:Z; EggNog:ENOG410PHTB; InterPro:IPR013809,IPR030224,IPR035964,IPR011417, IPR002558,IPR008942; PFAM:PF01608,PF07651; go_function: GO:0003779 - actin binding [Evidence IEA]; go_function: GO:0005543 - phospholipid binding [Evidence IEA]; go_function: GO:0030276 - clathrin binding [Evidence IEA]; go_process: GO:0006897 - endocytosis [Evidence IEA] AKAW2_80890A COG:S; EggNog:ENOG410PFA6; InterPro:IPR031468; TransMembrane:1 (i7-34o); go_function: GO:0008289 - lipid binding [Evidence IEA] AKAW2_80891S COG:S; EggNog:ENOG410PN0R; InterPro:IPR000073,IPR029058; PFAM:PF12697 AKAW2_80893A BUSCO:EOG092634B5; COG:H; EggNog:ENOG410PJ43; InterPro:IPR033749,IPR008949,IPR000092; PFAM:PF00348; go_process: GO:0008299 - isoprenoid biosynthetic process [Evidence IEA] AKAW2_80894A BUSCO:EOG09262CMP; COG:O; EggNog:ENOG410PFHZ; InterPro:IPR000717,IPR036390,IPR013586,IPR035267; PFAM:PF08375,PF01399; go_component: GO:0000502 - proteasome complex [Evidence IEA]; go_function: GO:0030234 - enzyme regulator activity [Evidence IEA]; go_process: GO:0042176 - regulation of protein catabolic process [Evidence IEA] AKAW2_80895S COG:S; EggNog:ENOG410PNCE; InterPro:IPR013966; go_component: GO:0005876 - spindle microtubule [Evidence IEA]; go_component: GO:0042729 - DASH complex [Evidence IEA]; go_process: GO:0008608 - attachment of spindle microtubules to kinetochore [Evidence IEA] AKAW2_80896S COG:K; EggNog:ENOG410PFPR; InterPro:IPR009072,IPR003228,IPR037794; PFAM:PF03847; go_component: GO:0000124 - SAGA complex [Evidence IEA]; go_component: GO:0005669 - transcription factor TFIID complex [Evidence IEA]; go_component: GO:0046695 - SLIK (SAGA-like) complex [Evidence IEA]; go_function: GO:0046982 - protein heterodimerization activity [Evidence IEA]; go_process: GO:0006352 - DNA-templated transcription, initiation [Evidence IEA] AKAW2_80897A TransMembrane:3 (i7-29o110-136i157-174o) AKAW2_80898A COG:T; EggNog:ENOG410PH70; InterPro:IPR027483,IPR002498,IPR023610,IPR027484; PFAM:PF01504; go_function: GO:0016307 - phosphatidylinositol phosphate kinase activity [Evidence IEA]; go_process: GO:0046488 - phosphatidylinositol metabolic process [Evidence IEA] AKAW2_80899A COG:B; EggNog:ENOG410PYKB; InterPro:IPR005818,IPR005819,IPR036388,IPR036390; PFAM:PF00538; go_component: GO:0000786 - nucleosome [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_process: GO:0006334 - nucleosome assembly [Evidence IEA] AKAW2_80900A BUSCO:EOG092634B1; COG:L; EggNog:ENOG410PFFR; InterPro:IPR023426,IPR006086,IPR006084,IPR006085, IPR019974,IPR029060,IPR036279,IPR008918; PFAM:PF00867,PF00752; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0004518 - nuclease activity [Evidence IEA]; go_function: GO:0016788 - hydrolase activity, acting on ester bonds [Evidence IEA] AKAW2_80901S COG:S; EggNog:ENOG410PICM; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172; TransMembrane:1 (o547-565i); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_80902S COG:I; EggNog:ENOG410PFTG; InterPro:IPR006091,IPR009075,IPR037069,IPR009100, IPR036250,IPR013786; PFAM:PF02770,PF00441,PF02771,PF08028; go_function: GO:0016627 - oxidoreductase activity, acting on the CH-CH group of donors [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_80903S COG:O; EggNog:ENOG410PI8T; InterPro:IPR016135,IPR023313,IPR000608; PFAM:PF00179 AKAW2_80904S COG:T; EggNog:ENOG410PV4K; InterPro:IPR000719,IPR011009,IPR008271; PFAM:PF00069; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_80906A COG:E; EggNog:ENOG410PW2Z; InterPro:IPR037523,IPR029068 AKAW2_80907A BUSCO:EOG09263DFA; COG:J; EggNog:ENOG410PGWK; InterPro:IPR029028,IPR005304,IPR029026; PFAM:PF03587; go_function: GO:0008168 - methyltransferase activity [Evidence IEA] AKAW2_80908S COG:L; EggNog:ENOG410PMEH; InterPro:IPR028009,IPR033257,IPR028005; PFAM:PF13880,PF13878; go_function: GO:0016407 - acetyltransferase activity [Evidence IEA]; go_process: GO:0000070 - mitotic sister chromatid segregation [Evidence IEA]; go_process: GO:0007062 - sister chromatid cohesion [Evidence IEA]; go_process: GO:0045132 - meiotic chromosome segregation [Evidence IEA] AKAW2_80909S COG:S; EggNog:ENOG410Q0TJ AKAW2_80910A COG:S; EggNog:ENOG410PS39 AKAW2_80911A COG:G; EggNog:ENOG410PHUS; InterPro:IPR036259; PFAM:PF13347; TransMembrane:12 (i38-56o68-89i110-128o148-167i203-221o227-247i285-307o340- 361i392-410o416-439i486-509o529-548i) AKAW2_80912S CAZy:GT8; COG:G; EggNog:ENOG410PM9M; InterPro:IPR029044,IPR002495; PFAM:PF01501; go_function: GO:0016757 - transferase activity, transferring glycosyl groups [Evidence IEA] AKAW2_80913S COG:S; EggNog:ENOG410PPBT AKAW2_80914S BUSCO:EOG0926142H; COG:J; EggNog:ENOG410PIFZ; InterPro:IPR015943,IPR013979,IPR011387; PFAM:PF08662; go_function: GO:0003743 - translation initiation factor activity [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0006413 - translational initiation [Evidence IEA] AKAW2_80915A COG:S; EggNog:ENOG410PMKM; InterPro:IPR015943,IPR036322; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_80916S BUSCO:EOG0926049S; COG:D; EggNog:ENOG410PHFM; InterPro:IPR024990; PFAM:PF12859; TransMembrane:7 (o815-832i1400-1420o1440-1458i1630-1647o1690-1708i1728- 1746o1752-1769i); go_component: GO:0005680 - anaphase-promoting complex [Evidence IEA] AKAW2_80917A BUSCO:EOG092606AD; COG:K; EggNog:ENOG410PI3M; InterPro:IPR013930,IPR039913,IPR013929; PFAM:PF08620,PF08621; go_process: GO:0006366 - transcription by RNA polymerase II [Evidence IEA] AKAW2_80918S COG:S; EggNog:ENOG410PHVI; InterPro:IPR014840; PFAM:PF08729 AKAW2_80919A COG:T; EggNog:ENOG410PFNY; InterPro:IPR017441,IPR008271,IPR000719,IPR011009; PFAM:PF07714,PF00069; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_80920S BUSCO:EOG09260492; COG:K; EggNog:ENOG410PFNW; InterPro:IPR028231,IPR003029,IPR042066,IPR000980, IPR032706,IPR012340,IPR023319,IPR012337,IPR037027, IPR028088,IPR017072,IPR035019,IPR035018,IPR028083, IPR035420,IPR036860,IPR041692,IPR023323,IPR010994; PFAM:PF14632,PF14633,PF17674,PF14635,PF14639, PF00017,PF14641; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_process: GO:0006139 - nucleobase-containing compound metabolic process [Evidence IEA]; go_process: GO:0032968 - positive regulation of transcription elongation from RNA polymerase II promoter [Evidence IEA] AKAW2_80921S BUSCO:EOG09261QYO; COG:T; EggNog:ENOG410PHWU; InterPro:IPR041680,IPR011993,IPR001849,IPR036598, IPR037239,IPR000648,IPR009038; PFAM:PF01237,PF15409,PF00169; go_function: GO:0008289 - lipid binding [Evidence IEA] AKAW2_80922A COG:S; EggNog:ENOG410PJ54; InterPro:IPR039777,IPR016024,IPR007701; PFAM:PF05004 AKAW2_80923A BUSCO:EOG09263IQ5; COG:J; EggNog:ENOG410PK9Y; InterPro:IPR012340,IPR026699,IPR025721,IPR036612; PFAM:PF14382; go_component: GO:0000178 - exosome (RNase complex) [Evidence IEA]; go_function: GO:0003723 - RNA binding [Evidence IEA] AKAW2_80924A COG:S; EggNog:ENOG410PRHE; InterPro:IPR032742; PFAM:PF14612; go_component: GO:0005634 - nucleus [Evidence IEA]; go_component: GO:0031011 - Ino80 complex [Evidence IEA]; go_process: GO:0006338 - chromatin remodeling [Evidence IEA] AKAW2_80925S BUSCO:EOG092645U1; COG:K; EggNog:ENOG410PJIH; InterPro:IPR000504,IPR012677,IPR035979; PFAM:PF00076; go_function: GO:0003676 - nucleic acid binding [Evidence IEA] AKAW2_80926S COG:S; EggNog:ENOG410PKWB; InterPro:IPR018545; PFAM:PF09405 AKAW2_80927S COG:S; EggNog:ENOG410QEAD; InterPro:IPR032350,IPR043145,IPR013783,IPR000433; PFAM:PF16158,PF00569; go_function: GO:0008270 - zinc ion binding [Evidence IEA] AKAW2_80928S COG:S; EggNog:ENOG410PK05; InterPro:IPR011042 AKAW2_80929A COG:Q; EggNog:ENOG410PQ1X; InterPro:IPR000868,IPR036380; PFAM:PF00857 AKAW2_80930S COG:S; EggNog:ENOG410PRP5; TransMembrane:1 (i197-221o) AKAW2_80931A COG:K; EggNog:ENOG410PJCC; InterPro:IPR000679,IPR035965,IPR013088,IPR013655, IPR000014; PFAM:PF13426,PF08447,PF00320; go_function: GO:0005515 - protein binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_function: GO:0043565 - sequence-specific DNA binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_80932S COG:S; EggNog:ENOG410PGA4; InterPro:IPR001806,IPR027417,IPR005225; PFAM:PF00071,PF08477; go_function: GO:0003924 - GTPase activity [Evidence IEA]; go_function: GO:0005525 - GTP binding [Evidence IEA] AKAW2_80933S COG:K; EggNog:ENOG410PSDI AKAW2_80934S COG:G; EggNog:ENOG410PGD8; InterPro:IPR014718,IPR008183,IPR018052,IPR011013; PFAM:PF01263; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0016853 - isomerase activity [Evidence IEA]; go_function: GO:0030246 - carbohydrate binding [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_80935S COG:F; EggNog:ENOG410PG9R; InterPro:IPR027277,IPR002638,IPR022412,IPR037128, IPR036068,IPR013785,IPR004393; PFAM:PF02749,PF01729; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0004514 - nicotinate-nucleotide diphosphorylase (carboxylating) activity [Evidence IEA]; go_function: GO:0016763 - transferase activity, transferring pentosyl groups [Evidence IEA]; go_process: GO:0009435 - NAD biosynthetic process [Evidence IEA] AKAW2_80936A COG:S; EggNog:ENOG410PIYU; InterPro:IPR024545,IPR012943; PFAM:PF07989,PF12808; go_component: GO:0005815 - microtubule organizing center [Evidence IEA] AKAW2_80937A COG:U; EggNog:ENOG410PHQI; InterPro:IPR035999,IPR041681,IPR011993,IPR023394, IPR000904; PFAM:PF15410,PF01369; go_function: GO:0005086 - ARF guanyl-nucleotide exchange factor activity [Evidence IEA]; go_process: GO:0032012 - regulation of ARF protein signal transduction [Evidence IEA] AKAW2_80938S COG:S; EggNog:ENOG410PHGS; InterPro:IPR007881; PFAM:PF05216; TransMembrane:5 (o84-103i115-137o189-208i215-239o251-273i) AKAW2_80939A COG:S; EggNog:ENOG410PPX8; InterPro:IPR019380,IPR039876; PFAM:PF10252 AKAW2_80940A COG:G; EggNog:ENOG410PJIM; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i104-125o137-156i163-182o188-211i223-243o255-275i296- 320o326-351i363-383o389-414i426-447o453-475i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_80941A CAZy:GT20; COG:G; EggNog:ENOG410PI8E; InterPro:IPR001830,IPR003337,IPR006379,IPR036412, IPR023214; PFAM:PF00982,PF02358; TransMembrane:1 (o895-915i); go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_process: GO:0005992 - trehalose biosynthetic process [Evidence IEA] AKAW2_80942S COG:L; EggNog:ENOG410PX2Q; InterPro:IPR043519 AKAW2_80943A COG:I; EggNog:ENOG410PG35; InterPro:IPR025202,IPR015679,IPR001736,IPR001683, IPR036871; PFAM:PF00614; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0035091 - phosphatidylinositol binding [Evidence IEA] AKAW2_80944S COG:S; EggNog:ENOG410PMDM; InterPro:IPR029058 AKAW2_80945A COG:J; EggNog:ENOG410PMZG; InterPro:IPR036227,IPR001196,IPR021131,IPR030878; PFAM:PF00828; go_component: GO:0005840 - ribosome [Evidence IEA]; go_component: GO:0015934 - large ribosomal subunit [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_process: GO:0006412 - translation [Evidence IEA] AKAW2_80946A COG:L; EggNog:ENOG410PIVM; InterPro:IPR013020,IPR006554,IPR006555,IPR002464, IPR014013,IPR010614,IPR028331; PFAM:PF13307,PF06733; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0003678 - DNA helicase activity [Evidence IEA]; go_function: GO:0004386 - helicase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016818 - hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [Evidence IEA]; go_process: GO:0006139 - nucleobase-containing compound metabolic process [Evidence IEA] AKAW2_80947S COG:M,O,T; EggNog:ENOG410PGIR; InterPro:IPR019734,IPR011990,IPR013026,IPR006597; PFAM:PF08238; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_80948S COG:T; EggNog:ENOG410PRCG; InterPro:IPR040461,IPR010776,IPR036388; PFAM:PF07106; go_process: GO:0007131 - reciprocal meiotic recombination [Evidence IEA] AKAW2_80949S COG:O; EggNog:ENOG410QDJX; InterPro:IPR000571,IPR041367,IPR036855; PFAM:PF00642,PF14608,PF18044; go_function: GO:0046872 - metal ion binding [Evidence IEA] AKAW2_80950A COG:K; EggNog:ENOG410PFM0; InterPro:IPR036427,IPR027180,IPR001025,IPR018359, IPR043151,IPR037382,IPR001487; PFAM:PF01426,PF00439; go_component: GO:0016586 - RSC-type complex [Evidence IEA]; go_function: GO:0003682 - chromatin binding [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0006338 - chromatin remodeling [Evidence IEA] AKAW2_80951S BUSCO:EOG09263S1E; COG:O; EggNog:ENOG410PJ6G; InterPro:IPR039138,IPR003323,IPR038765,IPR013087; MEROPS:MER0116559; PFAM:PF02338; go_function: GO:0004843 - thiol-dependent ubiquitin-specific protease activity [Evidence IEA]; go_function: GO:0101005 - ubiquitinyl hydrolase activity [Evidence IEA]; go_process: GO:0016579 - protein deubiquitination [Evidence IEA]; go_process: GO:0030433 - ubiquitin-dependent ERAD pathway [Evidence IEA] AKAW2_80952A BUSCO:EOG09262GWQ; COG:D; EggNog:ENOG410PFQ8; InterPro:IPR000719,IPR011009,IPR008271; PFAM:PF00069; go_function: GO:0004672 - protein kinase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006468 - protein phosphorylation [Evidence IEA] AKAW2_80953S BUSCO:EOG0926079Q; COG:B,D; EggNog:ENOG410Q4UC; InterPro:IPR016024,IPR011989,IPR024324,IPR026971, IPR007673,IPR032682; PFAM:PF12717,PF12922; go_component: GO:0005634 - nucleus [Evidence IEA]; go_process: GO:0000278 - mitotic cell cycle [Evidence IEA]; go_process: GO:0007076 - mitotic chromosome condensation [Evidence IEA]; go_process: GO:0030261 - chromosome condensation [Evidence IEA] AKAW2_80954A COG:T; EggNog:ENOG410PK8Z; InterPro:IPR037239,IPR000648,IPR018494; PFAM:PF01237; go_function: GO:0008289 - lipid binding [Evidence IEA] AKAW2_80955A COG:O; EggNog:ENOG410PJGB; InterPro:IPR038765,IPR036959,IPR001578; MEROPS:MER0015601; PFAM:PF01088; go_function: GO:0004843 - thiol-dependent ubiquitin-specific protease activity [Evidence IEA]; go_process: GO:0006511 - ubiquitin-dependent protein catabolic process [Evidence IEA] AKAW2_80956S BUSCO:EOG092604ZZ; COG:U; EggNog:ENOG410PI54; InterPro:IPR037701; TransMembrane:3 (i66-82o94-114i121-142o); go_function: GO:0017056 - structural constituent of nuclear pore [Evidence IEA] AKAW2_80957A BUSCO:EOG09260FX0; COG:S; EggNog:ENOG410PG0T; InterPro:IPR035082,IPR043519,IPR005554,IPR035367, IPR035370,IPR035371,IPR035369,IPR035368; PFAM:PF17404,PF17405,PF17407,PF17403,PF03813, PF17406 AKAW2_80958S COG:E; EggNog:ENOG410PI7P; InterPro:IPR000277,IPR015424,IPR015421,IPR015422; PFAM:PF01053; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0030170 - pyridoxal phosphate binding [Evidence IEA]; go_process: GO:0019346 - transsulfuration [Evidence IEA] AKAW2_80959S COG:J; EggNog:ENOG410PQUD; InterPro:IPR024388; PFAM:PF12824 AKAW2_80960S BUSCO:EOG09261OIF; COG:E; EggNog:ENOG410PHND; InterPro:IPR002933,IPR017153,IPR011650; MEROPS:MER0026471; PFAM:PF07687,PF01546; go_function: GO:0016787 - hydrolase activity [Evidence IEA]; go_function: GO:0070573 - metallodipeptidase activity [Evidence IEA] AKAW2_80961S BUSCO:EOG092608RH; COG:L; EggNog:ENOG410PGUP; InterPro:IPR010935,IPR003395,IPR027417,IPR027132, IPR036277; PFAM:PF13476,PF13175,PF02463,PF06470; go_component: GO:0005694 - chromosome [Evidence IEA]; go_component: GO:0030915 - Smc5-Smc6 complex [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0000724 - double-strand break repair via homologous recombination [Evidence IEA]; go_process: GO:0006281 - DNA repair [Evidence IEA]; go_process: GO:0051276 - chromosome organization [Evidence IEA] AKAW2_80962S COG:A; EggNog:ENOG410PGHM; InterPro:IPR027417,IPR001650,IPR014014,IPR014001, IPR011545,IPR000629; PFAM:PF00270,PF00271; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0004386 - helicase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA] AKAW2_80963S COG:C; EggNog:ENOG410PI3U; InterPro:IPR018108,IPR023395,IPR002067; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_80964A COG:J; EggNog:ENOG410PH5G; InterPro:IPR005139,IPR000352; PFAM:PF00472,PF03462; go_function: GO:0003747 - translation release factor activity [Evidence IEA]; go_process: GO:0006415 - translational termination [Evidence IEA] AKAW2_80965S COG:O; EggNog:ENOG410PJCZ; InterPro:IPR011990,IPR001623,IPR036869,IPR019734, IPR013026; PFAM:PF00226; SECRETED:SignalP(1-20); go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_80966A COG:O; EggNog:ENOG410PKHZ; InterPro:IPR029063,IPR000682; PFAM:PF08241,PF01135,PF13649; go_function: GO:0004719 - protein-L-isoaspartate (D-aspartate) O-methyltransferase activity [Evidence IEA]; go_process: GO:0006464 - cellular protein modification process [Evidence IEA] AKAW2_80967S COG:S; EggNog:ENOG410Q2Q8 AKAW2_80968A BUSCO:EOG09263I7I; COG:C; EggNog:ENOG410PHAP; InterPro:IPR006255,IPR000089,IPR001078,IPR003016, IPR023213,IPR011053; PFAM:PF00364,PF00198; go_component: GO:0045252 - oxoglutarate dehydrogenase complex [Evidence IEA]; go_function: GO:0004149 - dihydrolipoyllysine-residue succinyltransferase activity [Evidence IEA]; go_function: GO:0016746 - transferase activity, transferring acyl groups [Evidence IEA]; go_process: GO:0006099 - tricarboxylic acid cycle [Evidence IEA] AKAW2_80969S COG:C; EggNog:ENOG410PQYY; InterPro:IPR008011,IPR033034; PFAM:PF05347; go_process: GO:0006120 - mitochondrial electron transport, NADH to ubiquinone [Evidence IEA] AKAW2_80970A COG:B; EggNog:ENOG410PNTK; InterPro:IPR002119,IPR032458,IPR007125,IPR009072, IPR032454; PFAM:PF00125,PF00808,PF16211; go_component: GO:0000786 - nucleosome [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0046982 - protein heterodimerization activity [Evidence IEA] AKAW2_80971S COG:B; EggNog:ENOG410PNT7; InterPro:IPR009072,IPR000558,IPR007125; PFAM:PF00125; go_component: GO:0000786 - nucleosome [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0046982 - protein heterodimerization activity [Evidence IEA] AKAW2_80972A BUSCO:EOG09264B3O; COG:O; EggNog:ENOG410PI8K; InterPro:IPR038765,IPR005078; MEROPS:MER0013559; PFAM:PF03416 AKAW2_80973S COG:S; EggNog:ENOG410QDR0; InterPro:IPR001374,IPR036867,IPR034082,IPR000467; PFAM:PF01585,PF01424; go_function: GO:0003676 - nucleic acid binding [Evidence IEA] AKAW2_80974A COG:O; EggNog:ENOG410PJS0; InterPro:IPR036236,IPR018253,IPR001623,IPR036869, IPR022755,IPR003604,IPR013087; PFAM:PF00226,PF12171,PF12874; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA] AKAW2_80975S COG:S; EggNog:ENOG410PHBI; InterPro:IPR036623,IPR001810,IPR032698,IPR011722, IPR036047; PFAM:PF08755,PF13369,PF12937; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_80976A COG:S; EggNog:ENOG410PIAS AKAW2_80977S BUSCO:EOG09262E3Q; COG:S; EggNog:ENOG410PG3P; InterPro:IPR015943,IPR001680,IPR036322,IPR017986; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_80978A COG:C; EggNog:ENOG410PGHW; InterPro:IPR016171,IPR006094,IPR036318,IPR004113, IPR016164,IPR016166; PFAM:PF02913,PF01565; TransMembrane:1 (i88-105o); go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_function: GO:0071949 - FAD binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_80979S COG:Q; EggNog:ENOG410PFUH; InterPro:IPR013154,IPR013149,IPR002328,IPR036291, IPR011032,IPR020843; PFAM:PF00107,PF08240; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_80980A COG:U; EggNog:ENOG410PMQ7; InterPro:IPR005225,IPR001806,IPR027417; PFAM:PF00025,PF08477,PF00071; go_function: GO:0003924 - GTPase activity [Evidence IEA]; go_function: GO:0005525 - GTP binding [Evidence IEA] AKAW2_80982A COG:S; EggNog:ENOG410PY7B AKAW2_80983S COG:S; EggNog:ENOG410PK96; InterPro:IPR043136,IPR035780 AKAW2_80985S CAZy:GT2_Glyco_tranf_2; COG:S; EggNog:ENOG410PJ0I; InterPro:IPR029044; PFAM:PF13506,PF00535,PF13641; TransMembrane:1 (i12-30o) AKAW2_80986S BUSCO:EOG09264L6D; COG:C; EggNog:ENOG410PHTY; InterPro:IPR023335,IPR042272,IPR011419; PFAM:PF07542; go_process: GO:0043461 - proton-transporting ATP synthase complex assembly [Evidence IEA] AKAW2_80987S COG:T; EggNog:ENOG410PFD5; InterPro:IPR000648,IPR011993,IPR002110,IPR018494, IPR020683,IPR036770,IPR037239,IPR001849; PFAM:PF13857,PF01237,PF00023,PF13637,PF00169, PF13606; go_function: GO:0005515 - protein binding [Evidence IEA]; go_function: GO:0008289 - lipid binding [Evidence IEA] AKAW2_80988S BUSCO:EOG09261OKK; COG:S; EggNog:ENOG410PHQR; InterPro:IPR032717; PFAM:PF13824 AKAW2_80989A SECRETED:SignalP(1-20) AKAW2_80990A COG:S; EggNog:ENOG410PQN4; SECRETED:SignalP(1-20) AKAW2_80991A COG:C; EggNog:ENOG410PGTW; InterPro:IPR036291,IPR012301,IPR012302,IPR001891, IPR015884,IPR037062; PFAM:PF00390,PF03949; go_function: GO:0004470 - malic enzyme activity [Evidence IEA]; go_function: GO:0004471 - malate dehydrogenase (decarboxylating) (NAD+) activity [Evidence IEA]; go_function: GO:0051287 - NAD binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_80992A COG:Q; EggNog:ENOG410PFAI; InterPro:IPR013154,IPR013149,IPR036291,IPR011032, IPR020843,IPR002364; PFAM:PF00107,PF08240,PF13602; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_80993A COG:S; EggNog:ENOG410PYTG; InterPro:IPR025676; PFAM:PF14420 AKAW2_80994A COG:K; EggNog:ENOG410PGN8; InterPro:IPR027417,IPR002464,IPR000330,IPR038718, IPR001650,IPR014012,IPR014001; PFAM:PF00176,PF07529,PF00271,PF04851; go_function: GO:0005524 - ATP binding [Evidence IEA] AKAW2_80995S COG:C; EggNog:ENOG410PPPV; InterPro:IPR008699; PFAM:PF05821; TransMembrane:1 (i99-120o); go_component: GO:0005739 - mitochondrion [Evidence IEA]; go_function: GO:0003954 - NADH dehydrogenase activity [Evidence IEA]; go_function: GO:0008137 - NADH dehydrogenase (ubiquinone) activity [Evidence IEA] AKAW2_80996S BUSCO:EOG092608WU; COG:S; EggNog:ENOG410PFJ4; InterPro:IPR019558,IPR035892,IPR014772,IPR000008, IPR014770; PFAM:PF00168 AKAW2_80997A COG:J; EggNog:ENOG410PP4P; InterPro:IPR006175,IPR006056,IPR019897,IPR035959; PFAM:PF01042 AKAW2_80998A COG:S; EggNog:ENOG410PP4V AKAW2_80999S BUSCO:EOG09264SSI; COG:F; EggNog:ENOG410PNKV; InterPro:IPR029057,IPR005764,IPR000836; PFAM:PF00156; go_component: GO:0005737 - cytoplasm [Evidence IEA]; go_function: GO:0003999 - adenine phosphoribosyltransferase activity [Evidence IEA]; go_process: GO:0006168 - adenine salvage [Evidence IEA]; go_process: GO:0009116 - nucleoside metabolic process [Evidence IEA] AKAW2_81000A COG:S; EggNog:ENOG410PYAE; InterPro:IPR036568,IPR017939,IPR013024; go_function: GO:0003839 - gamma-glutamylcyclotransferase activity [Evidence IEA] AKAW2_81001A CAZy:GH47; COG:G; EggNog:ENOG410PV2M; InterPro:IPR036026,IPR001382; PFAM:PF01532; go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0004571 - mannosyl-oligosaccharide 1,2-alpha-mannosidase activity [Evidence IEA]; go_function: GO:0005509 - calcium ion binding [Evidence IEA] AKAW2_81002A COG:S; EggNog:ENOG410PQPK; TransMembrane:2 (i160-180o192-211i) AKAW2_81003A COG:A; EggNog:ENOG410PJ2T; InterPro:IPR036322,IPR015943,IPR001680,IPR019775, IPR020472,IPR017986; PFAM:PF00400; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_81004S BUSCO:EOG09264OM7; COG:U; EggNog:ENOG410PK75; InterPro:IPR024096,IPR007194,IPR016721; PFAM:PF04051; go_component: GO:0030008 - TRAPP complex [Evidence IEA]; go_process: GO:0048193 - Golgi vesicle transport [Evidence IEA] AKAW2_81006S COG:S; EggNog:ENOG410PK2C; InterPro:IPR006594; PFAM:PF08513; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_81007A COG:S; EggNog:ENOG410PUEP AKAW2_81008A COG:S; EggNog:ENOG410PUEP AKAW2_81009A COG:A; EggNog:ENOG410PJ0H; InterPro:IPR000504,IPR012677,IPR035979; PFAM:PF00076; go_function: GO:0003676 - nucleic acid binding [Evidence IEA] AKAW2_81011A COG:S; EggNog:ENOG410PNKW; InterPro:IPR031349; PFAM:PF17110 AKAW2_81012A BUSCO:EOG092655SO; COG:A; EggNog:ENOG410PMUH; InterPro:IPR024326,IPR040447,IPR040446,IPR012677; PFAM:PF12923,PF17799 AKAW2_81013A COG:L; EggNog:ENOG410PGDF; InterPro:IPR016467,IPR027417,IPR003593,IPR011940, IPR010995,IPR033925,IPR020588,IPR020587,IPR013632; PFAM:PF08423,PF06745,PF14520,PF00154; go_component: GO:0005634 - nucleus [Evidence IEA]; go_function: GO:0000150 - recombinase activity [Evidence IEA]; go_function: GO:0000166 - nucleotide binding [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0008094 - DNA-dependent ATPase activity [Evidence IEA]; go_process: GO:0006259 - DNA metabolic process [Evidence IEA]; go_process: GO:0006281 - DNA repair [Evidence IEA]; go_process: GO:0007131 - reciprocal meiotic recombination [Evidence IEA] AKAW2_81014A COG:O; EggNog:ENOG410PFIP; InterPro:IPR036875,IPR001878; PFAM:PF13917,PF00098; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA] AKAW2_81015A BUSCO:EOG09262MJW; COG:G; EggNog:ENOG410Q10S; InterPro:IPR029044,IPR039741,IPR002618; PFAM:PF01704; TransMembrane:1 (o481-499i); go_function: GO:0070569 - uridylyltransferase activity [Evidence IEA] AKAW2_81016A COG:O; EggNog:ENOG410PGW6; InterPro:IPR035538,IPR000504,IPR002130,IPR035979, IPR012677,IPR029000,IPR035542; PFAM:PF00160,PF00076; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0003755 - peptidyl-prolyl cis-trans isomerase activity [Evidence IEA]; go_process: GO:0000413 - protein peptidyl-prolyl isomerization [Evidence IEA] AKAW2_81017S COG:S; EggNog:ENOG410PTR1; InterPro:IPR036864,IPR001138; PFAM:PF00172; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_81018A COG:J; EggNog:ENOG410PNWS; InterPro:IPR018098,IPR012678,IPR001976; PFAM:PF01282; go_component: GO:0005840 - ribosome [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_process: GO:0006412 - translation [Evidence IEA] AKAW2_81019S COG:S; EggNog:ENOG410PHJK; InterPro:IPR029063,IPR019410; TransMembrane:1 (o289-310i) AKAW2_81020A COG:S; EggNog:ENOG410PM8S AKAW2_81021A COG:S; EggNog:ENOG410PIJK; InterPro:IPR024964,IPR035782,IPR043136,IPR013320, IPR001870,IPR003877,IPR006594,IPR006595,IPR013144; PFAM:PF10607,PF00622; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_81022A COG:S; EggNog:ENOG410PQU9; InterPro:IPR013175; PFAM:PF08193; go_component: GO:0031011 - Ino80 complex [Evidence IEA]; go_process: GO:0006338 - chromatin remodeling [Evidence IEA] AKAW2_81024A COG:O; EggNog:ENOG410PKM2; InterPro:IPR001623,IPR036869; PFAM:PF00226; TransMembrane:5 (o6-28i49-65o164-182i194-215o235-257i) AKAW2_81025S COG:K; EggNog:ENOG410PJB3; InterPro:IPR036898,IPR041178; PFAM:PF17875 AKAW2_81026A COG:Q; EggNog:ENOG410PIC8; InterPro:IPR036188,IPR017941,IPR028202,IPR036922, IPR023753,IPR016156; PFAM:PF07992,PF00355,PF00070,PF14759; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_function: GO:0051537 - 2 iron, 2 sulfur cluster binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_81027A COG:S; EggNog:ENOG410PPIK; InterPro:IPR039715 AKAW2_81028A COG:S; EggNog:ENOG410PH88; InterPro:IPR011021; PFAM:PF00339 AKAW2_81029A COG:I; EggNog:ENOG410PHGN; InterPro:IPR029058 AKAW2_81030A COG:I; EggNog:ENOG410PHGN; InterPro:IPR029058 AKAW2_81031A BUSCO:EOG09265PWR; COG:C; EggNog:ENOG410PR2G; InterPro:IPR005124,IPR028987; PFAM:PF03179; go_component: GO:0016471 - vacuolar proton-transporting V-type ATPase complex [Evidence IEA]; go_function: GO:0042626 - ATPase-coupled transmembrane transporter activity [Evidence IEA]; go_process: GO:1902600 - proton transmembrane transport [Evidence IEA] AKAW2_81032S BUSCO:EOG09265K5D; COG:S; EggNog:ENOG410PSHG; InterPro:IPR031568; PFAM:PF15786; TransMembrane:1 (i7-26o) AKAW2_81033S COG:E; EggNog:ENOG410PJTQ; InterPro:IPR037217,IPR000898; PFAM:PF01231; go_function: GO:0020037 - heme binding [Evidence IEA]; go_function: GO:0046872 - metal ion binding [Evidence IEA]; go_process: GO:0019441 - tryptophan catabolic process to kynurenine [Evidence IEA] AKAW2_81034S COG:Q; EggNog:ENOG410PJ3Q; InterPro:IPR013154,IPR013149,IPR002328,IPR036291, IPR011032; PFAM:PF00107,PF08240,PF13602; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_81035A COG:S; EggNog:ENOG410PH0B; InterPro:IPR036864,IPR001138; PFAM:PF00172; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_81036A COG:S; EggNog:ENOG410PSWN AKAW2_81037S COG:S; EggNog:ENOG410PMCG; InterPro:IPR011502 AKAW2_81038A CAZy:CE10; COG:I; EggNog:ENOG410PM0R; InterPro:IPR001375,IPR029058,IPR013094; go_function: GO:0008236 - serine-type peptidase activity [Evidence IEA]; go_function: GO:0016787 - hydrolase activity [Evidence IEA]; go_process: GO:0006508 - proteolysis [Evidence IEA] AKAW2_81039A COG:S; EggNog:ENOG410PHPS; InterPro:IPR013783,IPR014756 AKAW2_81040A COG:K; EggNog:ENOG410PIQ7; InterPro:IPR007120,IPR007121,IPR037034,IPR037033, IPR015712,IPR014724,IPR007642,IPR007641,IPR007647, IPR007646,IPR007645,IPR007644; PFAM:PF04561,PF00562,PF04567,PF04566,PF04563, PF04565,PF04560; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0003899 - DNA-directed 5'-3' RNA polymerase activity [Evidence IEA]; go_function: GO:0032549 - ribonucleoside binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA] AKAW2_81041A COG:S; EggNog:ENOG410PI7N; InterPro:IPR016024,IPR011989,IPR013180,IPR039678; PFAM:PF08216 AKAW2_81042S COG:S; EggNog:ENOG410PTJ0; InterPro:IPR020266; PFAM:PF17112; TransMembrane:1 (o32-55i); go_component: GO:0005742 - mitochondrial outer membrane translocase complex [Evidence IEA]; go_process: GO:0030150 - protein import into mitochondrial matrix [Evidence IEA] AKAW2_81043S COG:K; EggNog:ENOG410Q22M; InterPro:IPR007219; PFAM:PF04082; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA] AKAW2_81044A BUSCO:EOG09262KJA; COG:H; EggNog:ENOG410PG8T; InterPro:IPR040727,IPR007229,IPR036068,IPR006406, IPR041525; PFAM:PF04095,PF17767; go_function: GO:0004514 - nicotinate-nucleotide diphosphorylase (carboxylating) activity [Evidence IEA]; go_function: GO:0004516 - nicotinate phosphoribosyltransferase activity [Evidence IEA]; go_process: GO:0009435 - NAD biosynthetic process [Evidence IEA] AKAW2_81045S COG:B; EggNog:ENOG410PJCW; InterPro:IPR028651,IPR019787,IPR019786,IPR011011, IPR024610,IPR001965,IPR013083; PFAM:PF12998 AKAW2_81046A TransMembrane:4 (o62-84i225-248o260-287i308-328o) AKAW2_81047A BUSCO:EOG092646WF; COG:K; EggNog:ENOG410PFKU; InterPro:IPR016049,IPR036388,IPR007832,IPR036390; PFAM:PF05158; go_component: GO:0005666 - RNA polymerase III complex [Evidence IEA]; go_process: GO:0006383 - transcription by RNA polymerase III [Evidence IEA] AKAW2_81048S BUSCO:EOG09261TEQ; COG:O; EggNog:ENOG410PITI; InterPro:IPR011990,IPR013105,IPR019734,IPR006636, IPR041243,IPR013026; PFAM:PF07719,PF17830,PF13424,PF13432,PF13176, PF13181,PF13414; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_81049S COG:S; EggNog:ENOG410PI2D; InterPro:IPR037756,IPR017147,IPR037765,IPR035892, IPR037761,IPR037762,IPR000008,IPR031468; PFAM:PF00168; TransMembrane:1 (o194-217i); go_function: GO:0008289 - lipid binding [Evidence IEA]; go_process: GO:0061817 - endoplasmic reticulum-plasma membrane tethering [Evidence IEA] AKAW2_81050S COG:G; EggNog:ENOG410PIQZ; InterPro:IPR029044,IPR016267,IPR002618; PFAM:PF01704; go_function: GO:0003983 - UTP:glucose-1-phosphate uridylyltransferase activity [Evidence IEA]; go_function: GO:0070569 - uridylyltransferase activity [Evidence IEA]; go_process: GO:0006011 - UDP-glucose metabolic process [Evidence IEA] AKAW2_81051S COG:K; EggNog:ENOG410Q1FS; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_81052S COG:K; EggNog:ENOG410Q2SA; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_81053A COG:M; EggNog:ENOG410Q4IV; InterPro:IPR002110,IPR027417,IPR007111,IPR036770, IPR020683; PFAM:PF05729,PF12796,PF00023,PF13606; TransMembrane:1 (o540-558i); go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_81054A COG:S; EggNog:ENOG410Q1RY; InterPro:IPR017956,IPR000116; go_component: GO:0000785 - chromatin [Evidence IEA]; go_component: GO:0005634 - nucleus [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_81055A COG:P; EggNog:ENOG410PI7D; InterPro:IPR004695,IPR038665; PFAM:PF03595; TransMembrane:10 (i30-48o54-79i100-124o130-155i167-190o196-222i234-257o277- 298i310-329o341-365i); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_81056A COG:Q; EggNog:ENOG410PIFN; InterPro:IPR004294; PFAM:PF03055; go_function: GO:0016702 - oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_81058S COG:S; EggNog:ENOG410PKZN; InterPro:IPR002110,IPR020683,IPR036770; PFAM:PF00023,PF12796; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_81059S COG:J; EggNog:ENOG410PGFR; InterPro:IPR001810,IPR036047; PFAM:PF00646; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_81060S COG:I; EggNog:ENOG410PKI5; InterPro:IPR022237,IPR003817; PFAM:PF12588,PF02666; go_function: GO:0004609 - phosphatidylserine decarboxylase activity [Evidence IEA]; go_process: GO:0008654 - phospholipid biosynthetic process [Evidence IEA] AKAW2_81061A COG:E; EggNog:ENOG410PFSG; InterPro:IPR004839,IPR015424,IPR015421,IPR015422; PFAM:PF00155; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0030170 - pyridoxal phosphate binding [Evidence IEA]; go_process: GO:0009058 - biosynthetic process [Evidence IEA] AKAW2_81062A COG:S; EggNog:ENOG410PUJC; InterPro:IPR023213,IPR003480; PFAM:PF02458; go_function: GO:0016747 - transferase activity, transferring acyl groups other than amino-acyl groups [Evidence IEA] AKAW2_81063A COG:G; EggNog:ENOG410PHMS; InterPro:IPR020846,IPR005828,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i56-83o95-116i123-142o148-169i176-200o220-244i339- 360o380-402i414-432o438-460i472-494o500-521i); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_81064A COG:G; EggNog:ENOG410PHHF; InterPro:IPR012334,IPR011050 AKAW2_81065A CAZy:GH28; COG:G; EggNog:ENOG410PHHF; InterPro:IPR000743,IPR012334,IPR011050; PFAM:PF00295; SECRETED:SignalP(1-18); go_function: GO:0004650 - polygalacturonase activity [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_81066A COG:S; EggNog:ENOG410PX0K; InterPro:IPR003848,IPR014729 AKAW2_81067S COG:T; EggNog:ENOG410PVJP; InterPro:IPR019819,IPR019826,IPR002018,IPR029058; MEROPS:MER0033235; PFAM:PF00135; SECRETED:SignalP(1-18) AKAW2_81068A COG:S; EggNog:ENOG410PQB9 AKAW2_81069S COG:S; EggNog:ENOG410Q2KD; TransMembrane:1 (i51-75o) AKAW2_81070S COG:I,J,T; EggNog:ENOG410PIXP; InterPro:IPR023631,IPR036928; PFAM:PF01425 AKAW2_81071S COG:S; EggNog:ENOG410PWCI; InterPro:IPR021858 AKAW2_81072A COG:U; EggNog:ENOG410PGXU; InterPro:IPR011701,IPR036259; PFAM:PF07690; TransMembrane:11 (i129-152o187-207i214-234o240-260i272-294o306-325i430- 452o472-492i499-532o557-580i592-611o); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_81073S COG:S; EggNog:ENOG410Q2ED; InterPro:IPR036864,IPR021858,IPR001138; PFAM:PF00172; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_81074A COG:K; EggNog:ENOG410PG60; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_81075A COG:O; EggNog:ENOG410PN5M; InterPro:IPR001841,IPR017455,IPR011011,IPR000306, IPR013083; PFAM:PF13639,PF01363; go_function: GO:0046872 - metal ion binding [Evidence IEA] AKAW2_81076A COG:S; EggNog:ENOG410PJ7R; InterPro:IPR032800,IPR010308,IPR040241; PFAM:PF06011,PF14558; TransMembrane:10 (o46-63i253-274o387-408i434-457o463-484i496-513o519- 538i543-562o574-594i606-628o) AKAW2_81077S COG:S; EggNog:ENOG410PFEQ AKAW2_81078S COG:E; EggNog:ENOG410PFYU; InterPro:IPR000277,IPR015424,IPR015421,IPR015422; PFAM:PF01053; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0030170 - pyridoxal phosphate binding [Evidence IEA]; go_process: GO:0019346 - transsulfuration [Evidence IEA] AKAW2_81079S COG:O; EggNog:ENOG410PRYF; InterPro:IPR012675,IPR016155,IPR028887,IPR003749; PFAM:PF02597; go_component: GO:0005829 - cytosol [Evidence IEA]; go_process: GO:0006777 - Mo-molybdopterin cofactor biosynthetic process [Evidence IEA] AKAW2_81080A COG:S; EggNog:ENOG410PSE4; TransMembrane:4 (i12-34o46-68i75-96o156-178i) AKAW2_81081S BUSCO:EOG09260JNY; COG:J; EggNog:ENOG410PKE6; InterPro:IPR012340,IPR001900; PFAM:PF00773; go_function: GO:0003723 - RNA binding [Evidence IEA]; go_function: GO:0004540 - ribonuclease activity [Evidence IEA] AKAW2_81082A COG:Q; EggNog:ENOG410PKH2; InterPro:IPR001128,IPR002403,IPR036396; PFAM:PF00067; go_function: GO:0004497 - monooxygenase activity [Evidence IEA]; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_81083A COG:I; EggNog:ENOG410PKQX; InterPro:IPR042099,IPR000873,IPR025110; PFAM:PF00501,PF13193 AKAW2_81084S BUSCO:EOG09265LEG; COG:T; EggNog:ENOG410PS86; InterPro:IPR002634,IPR036065; PFAM:PF01722 AKAW2_81085A COG:U; EggNog:ENOG410PK20; InterPro:IPR006011,IPR010989,IPR000727; PFAM:PF05739,PF00804; TransMembrane:1 (i251-271o); go_component: GO:0016020 - membrane [Evidence IEA]; go_process: GO:0016192 - vesicle-mediated transport [Evidence IEA] AKAW2_81086A COG:E; EggNog:ENOG410Q5CS; InterPro:IPR000109,IPR036259; PFAM:PF00854; TransMembrane:11 (o36-55i62-84o90-116i146-167o173-194i255-272o302-319i331- 353o387-408i420-441o447-467i); go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_81087A COG:G; EggNog:ENOG410QD9U; InterPro:IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i55-75o95-114i126-144o150-170i182-202o214-234i255- 278o298-315i322-342o348-373i385-407o413-437i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_81088S COG:E; EggNog:ENOG410PJXQ; InterPro:IPR036526,IPR044149,IPR003010; PFAM:PF00795; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_process: GO:0006807 - nitrogen compound metabolic process [Evidence IEA] AKAW2_81089A COG:S; EggNog:ENOG410PJNZ; InterPro:IPR018163,IPR012947,IPR009000,IPR018165; go_function: GO:0000166 - nucleotide binding [Evidence IEA]; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0004812 - aminoacyl-tRNA ligase activity [Evidence IEA]; go_function: GO:0004813 - alanine-tRNA ligase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006419 - alanyl-tRNA aminoacylation [Evidence IEA]; go_process: GO:0043039 - tRNA aminoacylation [Evidence IEA] AKAW2_81090A COG:E; EggNog:ENOG410PRK8; InterPro:IPR001518,IPR014729,IPR024074; PFAM:PF00764; go_function: GO:0004055 - argininosuccinate synthase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006526 - arginine biosynthetic process [Evidence IEA] AKAW2_81091S COG:Q; EggNog:ENOG410PPGR; InterPro:IPR026992,IPR027443,IPR005123; PFAM:PF03171,PF14226; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_81092S COG:S; EggNog:ENOG410PPIV; InterPro:IPR010730; PFAM:PF06985 AKAW2_81094A COG:S; EggNog:ENOG410PNBQ; InterPro:IPR029058,IPR018712; PFAM:PF09994; TransMembrane:1 (i350-370o) AKAW2_81093S COG:Q; EggNog:ENOG410PMGK; InterPro:IPR037120,IPR034812,IPR036396,IPR019791, IPR017972,IPR001128,IPR010255; PFAM:PF03098; SECRETED:SignalP(1-22); go_function: GO:0004601 - peroxidase activity [Evidence IEA]; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0006979 - response to oxidative stress [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_81096A BUSCO:EOG092646VF; COG:J; EggNog:ENOG410PHEP; InterPro:IPR001040,IPR019770,IPR023398; PFAM:PF01652; go_component: GO:0005737 - cytoplasm [Evidence IEA]; go_function: GO:0003723 - RNA binding [Evidence IEA]; go_function: GO:0003743 - translation initiation factor activity [Evidence IEA]; go_process: GO:0006413 - translational initiation [Evidence IEA] AKAW2_81097A COG:S; EggNog:ENOG410PNK9; InterPro:IPR007248; PFAM:PF04117; go_component: GO:0016021 - integral component of membrane [Evidence IEA] AKAW2_81098S BUSCO:EOG09264903; COG:J; EggNog:ENOG410PG67; InterPro:IPR018192,IPR005324,IPR013810,IPR000851, IPR020568,IPR005711,IPR014721; PFAM:PF03719,PF00333; go_component: GO:0005840 - ribosome [Evidence IEA]; go_component: GO:0015935 - small ribosomal subunit [Evidence IEA]; go_function: GO:0003723 - RNA binding [Evidence IEA]; go_function: GO:0003735 - structural constituent of ribosome [Evidence IEA]; go_process: GO:0006412 - translation [Evidence IEA] AKAW2_81099S COG:Q; EggNog:ENOG410PK87; InterPro:IPR001128,IPR002401,IPR036396; PFAM:PF00067; TransMembrane:2 (o6-23i35-55o); go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_81100S COG:S; EggNog:ENOG410Q0B0 AKAW2_81101S COG:S; EggNog:ENOG410PZ23 AKAW2_81103A COG:S; EggNog:ENOG410Q0IA; InterPro:IPR001425; PFAM:PF01036; TransMembrane:7 (o47-66i75-94o130-148i155-176o182-200i221-245o251-270i); go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0005216 - ion channel activity [Evidence IEA]; go_process: GO:0006811 - ion transport [Evidence IEA] AKAW2_81104A COG:S; EggNog:ENOG410PWV9; InterPro:IPR001810,IPR036047,IPR032675; PFAM:PF12937; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_81105A BUSCO:EOG092609JB; COG:J; EggNog:ENOG410PGFU; InterPro:IPR013155,IPR023585,IPR001412,IPR033708, IPR014729,IPR009008,IPR002301,IPR002300,IPR009080; PFAM:PF08264,PF00133; go_function: GO:0000049 - tRNA binding [Evidence IEA]; go_function: GO:0000166 - nucleotide binding [Evidence IEA]; go_function: GO:0002161 - aminoacyl-tRNA editing activity [Evidence IEA]; go_function: GO:0004812 - aminoacyl-tRNA ligase activity [Evidence IEA]; go_function: GO:0004822 - isoleucine-tRNA ligase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006418 - tRNA aminoacylation for protein translation [Evidence IEA]; go_process: GO:0006428 - isoleucyl-tRNA aminoacylation [Evidence IEA] AKAW2_81106A COG:S; EggNog:ENOG410PJ3C; InterPro:IPR005373,IPR039156; PFAM:PF03676 AKAW2_81107S COG:Z; EggNog:ENOG410PFMI; InterPro:IPR019821,IPR036961,IPR027417,IPR001752, IPR025901; PFAM:PF16796,PF00225; go_function: GO:0003777 - microtubule motor activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0008017 - microtubule binding [Evidence IEA]; go_process: GO:0007018 - microtubule-based movement [Evidence IEA] AKAW2_81108A COG:D; EggNog:ENOG410PQNC AKAW2_81109A COG:D; EggNog:ENOG410PQNC; InterPro:IPR024991,IPR013083; PFAM:PF12861,PF12678; go_component: GO:0005680 - anaphase-promoting complex [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_function: GO:0061630 - ubiquitin protein ligase activity [Evidence IEA]; go_function: GO:0097602 - cullin family protein binding [Evidence IEA]; go_process: GO:0031145 - anaphase-promoting complex-dependent catabolic process [Evidence IEA] AKAW2_81110S BUSCO:EOG09263FGN; COG:V; EggNog:ENOG410PIFM; InterPro:IPR001763,IPR036873; PFAM:PF00581 AKAW2_81111S COG:S; EggNog:ENOG410PR6K AKAW2_81112S COG:S; EggNog:ENOG410PRFU; InterPro:IPR043451,IPR004018; PFAM:PF02755 AKAW2_81113A COG:J; EggNog:ENOG410PP9E; InterPro:IPR016069,IPR016068,IPR002848,IPR036081; PFAM:PF01997; go_function: GO:0043565 - sequence-specific DNA binding [Evidence IEA] AKAW2_81114A COG:G; EggNog:ENOG410Q1Z7; InterPro:IPR005829,IPR005828,IPR003663,IPR036259, IPR020846; PFAM:PF00083,PF07690; TransMembrane:10 (i21-39o72-89i101-118o130-148i160-181o193-215i287-305o325- 347i356-376o396-416i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_81115S COG:G; EggNog:ENOG410PM67; InterPro:IPR011042,IPR005511,IPR013658; PFAM:PF08450 AKAW2_81116A COG:E; EggNog:ENOG410PW0F; InterPro:IPR006140,IPR036291,IPR006139,IPR029753, IPR029752; PFAM:PF00389,PF02826; go_function: GO:0016616 - oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Evidence IEA]; go_function: GO:0051287 - NAD binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_81117A COG:S; EggNog:ENOG410PN31; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF04082; TransMembrane:1 (o314-335i); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_81118S COG:S; EggNog:ENOG410PV1E; InterPro:IPR001138,IPR007219,IPR036864; PFAM:PF00172,PF04082; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_81119A COG:G; EggNog:ENOG410PNY4; InterPro:IPR005000,IPR015813,IPR040442; PFAM:PF03328; go_function: GO:0003824 - catalytic activity [Evidence IEA] AKAW2_81120A COG:G; EggNog:ENOG410QDHW; InterPro:IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i57-74o98-120i127-151o157-177i189-209o221-243i294- 311o331-349i361-379o385-405i417-439o451-472i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_81121A COG:S; EggNog:ENOG410PIGC; InterPro:IPR043129 AKAW2_81122S COG:S; EggNog:ENOG410Q0NU; TransMembrane:1 (o76-100i) AKAW2_81123A COG:S; EggNog:ENOG410PZ0M AKAW2_81124A SECRETED:SignalP(1-15) AKAW2_81125S COG:S; EggNog:ENOG410PUFP; InterPro:IPR011009,IPR002575; PFAM:PF01636 AKAW2_81126A CAZy:AA3; COG:E; EggNog:ENOG410PM8U; InterPro:IPR012132,IPR036188,IPR000172,IPR007867; PFAM:PF05199,PF00732; go_function: GO:0016614 - oxidoreductase activity, acting on CH-OH group of donors [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_81127S COG:S; EggNog:ENOG410PXSX; TransMembrane:5 (o6-31i43-70o90-113i125-147o167-193i) AKAW2_81128A COG:S; EggNog:ENOG410PZSC; InterPro:IPR032710 AKAW2_81129S COG:S; EggNog:ENOG410PV3K; InterPro:IPR001279,IPR036866; PFAM:PF00753 AKAW2_81130A COG:S; EggNog:ENOG410PQAI; InterPro:IPR028116,IPR014347 AKAW2_81131A COG:S; EggNog:ENOG410PNYW; InterPro:IPR001279,IPR036866; PFAM:PF00753 AKAW2_81132A COG:S; EggNog:ENOG410PQAI; InterPro:IPR028116,IPR014347; PFAM:PF14832 AKAW2_81133S COG:O; EggNog:ENOG410Q2DE; InterPro:IPR000073,IPR029058; PFAM:PF12697,PF12146 AKAW2_81134A COG:S; EggNog:ENOG410PRC3; InterPro:IPR021765; go_process: GO:0043386 - mycotoxin biosynthetic process [Evidence IEA] AKAW2_81135S COG:O; EggNog:ENOG410PWTU; InterPro:IPR038765,IPR036959,IPR001578; MEROPS:MER0000836; PFAM:PF01088; go_function: GO:0004843 - thiol-dependent ubiquitin-specific protease activity [Evidence IEA]; go_process: GO:0006511 - ubiquitin-dependent protein catabolic process [Evidence IEA] AKAW2_81136A COG:K; EggNog:ENOG410PMPT; InterPro:IPR027417,IPR007111; PFAM:PF05729 AKAW2_81137S COG:L; EggNog:ENOG410PIVK; InterPro:IPR038718,IPR000330,IPR027417,IPR001650, IPR014001; PFAM:PF00176,PF00270,PF00271,PF04851; go_function: GO:0005524 - ATP binding [Evidence IEA] AKAW2_81138A CAZy:GH2; COG:G; EggNog:ENOG410PGNW; InterPro:IPR017853,IPR036156,IPR008979,IPR006102, IPR013783,IPR041447; PFAM:PF17786,PF00703; antiSMASH:Cluster_8.13; go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_81139S SECRETED:SignalP(1-19); antiSMASH:Cluster_8.13 AKAW2_81140S COG:K; EggNog:ENOG410PFNP; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; TransMembrane:3 (i295-313o361-378i575-594o); antiSMASH:Cluster_8.13; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_81141S BUSCO:EOG09261XAF; CAZy:GT50; COG:G; EggNog:ENOG410PH9I; InterPro:IPR007704; PFAM:PF06728,PF05007; TransMembrane:9 (i16-35o91-112i146-164o170-196i231-252o296-314i326- 351o363-380i392-416o); antiSMASH:Cluster_8.13; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0004376 - glycolipid mannosyltransferase activity [Evidence IEA]; go_function: GO:0051751 - alpha-1,4-mannosyltransferase activity [Evidence IEA]; go_process: GO:0006506 - GPI anchor biosynthetic process [Evidence IEA] AKAW2_81142A COG:I; EggNog:ENOG410PFJU; InterPro:IPR019845,IPR008949,IPR006449,IPR002060, IPR033904; PFAM:PF00494; TransMembrane:1 (o419-444i); antiSMASH:Cluster_8.13; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0004310 - farnesyl-diphosphate farnesyltransferase activity [Evidence IEA]; go_function: GO:0016740 - transferase activity [Evidence IEA]; go_function: GO:0016765 - transferase activity, transferring alkyl or aryl (other than methyl) groups [Evidence IEA]; go_function: GO:0051996 - squalene synthase activity [Evidence IEA]; go_process: GO:0008610 - lipid biosynthetic process [Evidence IEA]; go_process: GO:0009058 - biosynthetic process [Evidence IEA] AKAW2_81143S COG:O; EggNog:ENOG410PFZB; InterPro:IPR001623,IPR036869,IPR026894,IPR018253; PFAM:PF14308,PF00226; antiSMASH:Cluster_8.13 AKAW2_81144S COG:S; EggNog:ENOG410PGMK; InterPro:IPR016274,IPR000560,IPR029033; PFAM:PF00328; SECRETED:SignalP(1-18); antiSMASH:Cluster_8.13; go_function: GO:0016791 - phosphatase activity [Evidence IEA] AKAW2_81145A COG:S; EggNog:ENOG410PNPJ; antiSMASH:Cluster_8.13 AKAW2_81146A COG:L; EggNog:ENOG410PHKV; InterPro:IPR017961,IPR024728,IPR036775,IPR043502, IPR001126,IPR022880,IPR043128; PFAM:PF00817,PF11798,PF11799; antiSMASH:Cluster_8.13; go_function: GO:0003684 - damaged DNA binding [Evidence IEA]; go_function: GO:0003887 - DNA-directed DNA polymerase activity [Evidence IEA]; go_process: GO:0006281 - DNA repair [Evidence IEA] AKAW2_81147S COG:L; EggNog:ENOG410PGI8; InterPro:IPR032429,IPR008984,IPR000253,IPR040227; PFAM:PF00498,PF16508; go_component: GO:0030870 - Mre11 complex [Evidence IEA]; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0006302 - double-strand break repair [Evidence IEA]; go_process: GO:0007095 - mitotic G2 DNA damage checkpoint [Evidence IEA] AKAW2_81148S COG:S; EggNog:ENOG410PJF2 AKAW2_81149A COG:G; EggNog:ENOG410QDIH; InterPro:IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i68-85o109-127i134-156o168-190i199-220o226-250i292- 311o331-354i366-383o389-411i423-446o458-477i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_81150S COG:S; EggNog:ENOG410PS4G; InterPro:IPR012942; PFAM:PF07985 AKAW2_81151A COG:I; EggNog:ENOG410Q228; InterPro:IPR037143,IPR016035,IPR041550,IPR004568, IPR016039,IPR036291,IPR026025,IPR014030,IPR014031, IPR040899,IPR008278,IPR020841; PFAM:PF01648,PF00109,PF18325,PF02801,PF18314; go_component: GO:0005835 - fatty acid synthase complex [Evidence IEA]; go_function: GO:0000287 - magnesium ion binding [Evidence IEA]; go_function: GO:0004312 - fatty acid synthase activity [Evidence IEA]; go_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein] synthase activity [Evidence IEA]; go_function: GO:0004316 - 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity [Evidence IEA]; go_function: GO:0008897 - holo-[acyl-carrier-protein] synthase activity [Evidence IEA]; go_function: GO:0016746 - transferase activity, transferring acyl groups [Evidence IEA]; go_process: GO:0006633 - fatty acid biosynthetic process [Evidence IEA]; go_process: GO:0042759 - long-chain fatty acid biosynthetic process [Evidence IEA] AKAW2_81152S COG:I; EggNog:ENOG410Q1F8; InterPro:IPR032088,IPR003965,IPR029069,IPR039569, IPR001227,IPR014043,IPR002539,IPR040883,IPR016452, IPR016035,IPR013785,IPR013565; PFAM:PF17951,PF16073,PF01575,PF08354,PF00698, PF13452; SMCOG1021:malonyl CoA-acyl carrier protein transacylase; antiSMASH:Cluster_8.14; go_component: GO:0005835 - fatty acid synthase complex [Evidence IEA]; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0004312 - fatty acid synthase activity [Evidence IEA]; go_function: GO:0004313 - [acyl-carrier-protein] S-acetyltransferase activity [Evidence IEA]; go_function: GO:0004314 - [acyl-carrier-protein] S-malonyltransferase activity [Evidence IEA]; go_function: GO:0004317 - 3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity [Evidence IEA]; go_function: GO:0004318 - enoyl-[acyl-carrier-protein] reductase (NADH) activity [Evidence IEA]; go_function: GO:0016740 - transferase activity [Evidence IEA]; go_process: GO:0006633 - fatty acid biosynthetic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_81153A COG:I; EggNog:ENOG410PJJ4; InterPro:IPR036188,IPR002938; PFAM:PF01494; SMCOG1087:hypothetical protein; TransMembrane:1 (i7-28o); antiSMASH:Cluster_8.14; go_function: GO:0071949 - FAD binding [Evidence IEA] AKAW2_81154A COG:S; EggNog:ENOG410PNTZ; InterPro:IPR003480,IPR023213; PFAM:PF02458; antiSMASH:Cluster_8.14; go_function: GO:0016747 - transferase activity, transferring acyl groups other than amino-acyl groups [Evidence IEA] AKAW2_81155S COG:S; EggNog:ENOG410PJX8; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; antiSMASH:Cluster_8.14; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_81156S COG:I; EggNog:ENOG410PJBH; InterPro:IPR016036,IPR016035,IPR029063,IPR016039, IPR042104,IPR014030,IPR014031,IPR001227,IPR041068, IPR006162,IPR014043,IPR020806,IPR020841,IPR009081, IPR036736,IPR036291,IPR013217,IPR013120; PFAM:PF07993,PF00550,PF13649,PF02801,PF00698, PF01370,PF00109,PF08242,PF08241,PF18558; SMCOG1022:Beta-ketoacyl synthase; antiSMASH:Cluster_8.14; go_function: GO:0016740 - transferase activity [Evidence IEA]; go_function: GO:0016746 - transferase activity, transferring acyl groups [Evidence IEA]; go_function: GO:0031177 - phosphopantetheine binding [Evidence IEA] AKAW2_81157A COG:S; EggNog:ENOG410PS59; InterPro:IPR022085; PFAM:PF12311; antiSMASH:Cluster_8.14 AKAW2_81158S COG:S; EggNog:ENOG410PYHI; InterPro:IPR016191; SECRETED:SignalP(1-19); antiSMASH:Cluster_8.14; go_function: GO:0003723 - RNA binding [Evidence IEA]; go_function: GO:0004540 - ribonuclease activity [Evidence IEA] AKAW2_81159S COG:S; EggNog:ENOG410PYHI; InterPro:IPR016191,IPR008160; PFAM:PF01391; SECRETED:SignalP(1-19); antiSMASH:Cluster_8.14; go_function: GO:0003723 - RNA binding [Evidence IEA]; go_function: GO:0004540 - ribonuclease activity [Evidence IEA] AKAW2_81160A COG:Q; EggNog:ENOG410PK2P; InterPro:IPR001128,IPR002401,IPR036396; PFAM:PF00067; SMCOG1034:cytochrome P450; antiSMASH:Cluster_8.14; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_81161A COG:Q; EggNog:ENOG410PY8U; InterPro:IPR001128,IPR036396; TransMembrane:1 (o12-32i); antiSMASH:Cluster_8.14; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_81162S COG:S; EggNog:ENOG410PRPE; TransMembrane:2 (i30-54o66-88i); antiSMASH:Cluster_8.14 AKAW2_81163S COG:Q; EggNog:ENOG410PNBB; InterPro:IPR001128,IPR002403,IPR036396; SMCOG1034:cytochrome P450; TransMembrane:2 (o6-26i46-63o); antiSMASH:Cluster_8.14; go_function: GO:0004497 - monooxygenase activity [Evidence IEA]; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_81164S COG:K; EggNog:ENOG410PMZT; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_81165A COG:J; EggNog:ENOG410PR68; InterPro:IPR006175,IPR035959; PFAM:PF01042 AKAW2_81166S COG:S; EggNog:ENOG410PHU9 AKAW2_81167S COG:S; EggNog:ENOG410PNSX; InterPro:IPR008816,IPR011058,IPR036673; PFAM:PF08881,PF05433; go_component: GO:0019867 - outer membrane [Evidence IEA] AKAW2_81168S TransMembrane:2 (n9-27c31/32o47-66i98-116o) AKAW2_81169S COG:S; EggNog:ENOG410PT02; InterPro:IPR010730; PFAM:PF06985 AKAW2_81170S CAZy:GH6; COG:G; EggNog:ENOG410PGYJ; InterPro:IPR001524,IPR035971,IPR000254,IPR036434, IPR016288; PFAM:PF01341,PF00734; SECRETED:SignalP(1-18); go_component: GO:0005576 - extracellular region [Evidence IEA]; go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_function: GO:0030248 - cellulose binding [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA]; go_process: GO:0030245 - cellulose catabolic process [Evidence IEA] AKAW2_81171S COG:E; EggNog:ENOG410PQK9; InterPro:IPR041492,IPR006439,IPR023198,IPR006328, IPR036412,IPR023214; PFAM:PF13419; go_function: GO:0016787 - hydrolase activity [Evidence IEA]; go_function: GO:0019120 - hydrolase activity, acting on acid halide bonds, in C-halide compounds [Evidence IEA] AKAW2_81172A COG:G; EggNog:ENOG410QDA5; InterPro:IPR011701,IPR036259; TransMembrane:5 (o31-52i59-79o85-110i122-144o150-169i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_81173S COG:J; EggNog:ENOG410PH5K; InterPro:IPR036621,IPR006195,IPR004154,IPR027031, IPR033731,IPR002314,IPR002315; PFAM:PF03129; go_component: GO:0005737 - cytoplasm [Evidence IEA]; go_function: GO:0000166 - nucleotide binding [Evidence IEA]; go_function: GO:0004812 - aminoacyl-tRNA ligase activity [Evidence IEA]; go_function: GO:0004820 - glycine-tRNA ligase activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_process: GO:0006418 - tRNA aminoacylation for protein translation [Evidence IEA]; go_process: GO:0006426 - glycyl-tRNA aminoacylation [Evidence IEA] AKAW2_81176S COG:S; EggNog:ENOG410PZRK; InterPro:IPR011009 AKAW2_81177A COG:Q; EggNog:ENOG410QDST; InterPro:IPR036291,IPR002347; PFAM:PF08659,PF00106,PF13561; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_81178A COG:S; EggNog:ENOG410PI5Q; InterPro:IPR001279,IPR036866; PFAM:PF00753 AKAW2_81179S COG:I; EggNog:ENOG410PVEQ; InterPro:IPR002018,IPR029058; MEROPS:MER0030934; PFAM:PF00135; SECRETED:SignalP(1-21) AKAW2_81180S COG:S; EggNog:ENOG410PTVY AKAW2_81181S COG:E; EggNog:ENOG410PM6Y; InterPro:IPR017144,IPR002933,IPR011650,IPR017439, IPR036264; MEROPS:MER0014418; PFAM:PF01546,PF07687; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_81182S COG:G; EggNog:ENOG410PV0B; InterPro:IPR011701,IPR036259; PFAM:PF07690; TransMembrane:11 (o100-118i130-146o152-175i187-207o219-241i262-282o302- 320i327-347o353-377i389-412o418-442i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_81183A COG:S; EggNog:ENOG410PT2H; InterPro:IPR011011,IPR019786,IPR013083 AKAW2_81184S COG:S; EggNog:ENOG410PQV8; InterPro:IPR036864,IPR021858,IPR001138; PFAM:PF00172; TransMembrane:1 (i176-194o); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_81185A COG:K; EggNog:ENOG410PW9R; InterPro:IPR036864,IPR021858,IPR001138; PFAM:PF00172; TransMembrane:1 (o498-515i); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_81186S COG:S; EggNog:ENOG410PW4S; InterPro:IPR014710,IPR006045,IPR011051; PFAM:PF00190; SECRETED:SignalP(1-23) AKAW2_81187S COG:G; EggNog:ENOG410PVVB; InterPro:IPR013783,IPR026891; PFAM:PF14310 AKAW2_81188S COG:S; EggNog:ENOG410PVUI; InterPro:IPR036291,IPR008030; PFAM:PF13460,PF05368 AKAW2_81189S COG:I; EggNog:ENOG410Q1Y8; InterPro:IPR000873,IPR020845,IPR042099,IPR025110; PFAM:PF00501,PF13193; TransMembrane:2 (o42-62i200-218o) AKAW2_81190A CAZy:GH13; COG:M; EggNog:ENOG410PF9V; InterPro:IPR013534,IPR006047,IPR017853; PFAM:PF08323,PF00128; SECRETED:SignalP(1-19); TransMembrane:13 (n4-14c19/20o1075-1096i1978-1998o2010-2029i2036-2059o2071- 2091i2103-2124o2144-2167i2193-2210o2230-2253i2274- 2291o2303-2323i2330-2352o2372-2396i); go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_81191S CAZy:GH13; COG:G; EggNog:ENOG410Q2HI; InterPro:IPR006047,IPR015340,IPR017853,IPR013780, IPR013777; PFAM:PF00128,PF09260; SECRETED:SignalP(1-28); TransMembrane:1 (n15-26c33/34o530-548i); go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0004556 - alpha-amylase activity [Evidence IEA]; go_function: GO:0005509 - calcium ion binding [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA]; go_process: GO:0016052 - carbohydrate catabolic process [Evidence IEA] AKAW2_81192A COG:Q; EggNog:ENOG410PMGM; InterPro:IPR036291,IPR013968,IPR002347; PFAM:PF08659; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_81193S COG:S; EggNog:ENOG410PXVQ; InterPro:IPR021858 AKAW2_81194S COG:S; EggNog:ENOG410PYJ7; InterPro:IPR036864,IPR001138; PFAM:PF00172; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_81195S COG:C; EggNog:ENOG410PMCP; InterPro:IPR013154,IPR013149,IPR036291,IPR011032, IPR020843; PFAM:PF00107,PF08240; antiSMASH:Cluster_8.15; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_81196A COG:S; EggNog:ENOG410PU4M; antiSMASH:Cluster_8.15 AKAW2_81197A COG:Q; EggNog:ENOG410PNB7; InterPro:IPR002347,IPR036291,IPR020904; PFAM:PF00106,PF13561,PF08659; SMCOG1001:short-chain dehydrogenase/reductase SDR; antiSMASH:Cluster_8.15; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_81198S COG:S; EggNog:ENOG410PUCX; antiSMASH:Cluster_8.15 AKAW2_81199A COG:S; EggNog:ENOG410PR1M; InterPro:IPR043519; antiSMASH:Cluster_8.15 AKAW2_81200S COG:S; EggNog:ENOG410PZWF; InterPro:IPR006760; PFAM:PF04667; antiSMASH:Cluster_8.15 AKAW2_81201A COG:S; EggNog:ENOG410PYEB; TransMembrane:2 (o28-51i63-85o); antiSMASH:Cluster_8.15 AKAW2_81202A COG:K; EggNog:ENOG410Q1PJ; InterPro:IPR036864,IPR001138; PFAM:PF00172; TransMembrane:1 (o433-450i); antiSMASH:Cluster_8.15; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_81203S COG:C; EggNog:ENOG410Q1HM; InterPro:IPR036291,IPR008030; PFAM:PF13460,PF05368; SMCOG1199:NmrA family protein; antiSMASH:Cluster_8.15 AKAW2_81204A COG:C; EggNog:ENOG410PG0V; InterPro:IPR020471,IPR036812,IPR023210; PFAM:PF00248; SMCOG1039:aldo/keto reductase family oxidoreductase; antiSMASH:Cluster_8.15; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_81205A COG:I; EggNog:ENOG410PN2Q; InterPro:IPR025714,IPR029063; PFAM:PF13649,PF13489,PF08242,PF08241,PF07021, PF00891,PF13847; SMCOG1089:methyltransferase; antiSMASH:Cluster_8.15 AKAW2_81206A COG:Q; EggNog:ENOG410QD7U; InterPro:IPR016036,IPR016035,IPR016039,IPR010080, IPR042104,IPR014030,IPR011032,IPR013968,IPR001227, IPR032821,IPR014031,IPR014043,IPR020807,IPR020843, IPR020841,IPR029063,IPR036291,IPR013217,IPR013120; PFAM:PF16197,PF00109,PF13489,PF14765,PF02801, PF00698,PF07993,PF01073,PF13649,PF13602,PF01370,PF00107, PF00106,PF08242,PF08241,PF08659; SMCOG1022:Beta-ketoacyl synthase; antiSMASH:Cluster_8.15; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0016740 - transferase activity [Evidence IEA]; go_function: GO:0016746 - transferase activity, transferring acyl groups [Evidence IEA] AKAW2_81207S SECRETED:SignalP(1-22); antiSMASH:Cluster_8.15 AKAW2_81208S COG:Q; EggNog:ENOG410PMAN; InterPro:IPR002347,IPR036291,IPR020904; PFAM:PF00106,PF13561,PF08659; SMCOG1001:short-chain dehydrogenase/reductase SDR; antiSMASH:Cluster_8.15; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_81209S COG:Q; EggNog:ENOG410PM8C; InterPro:IPR001128,IPR036396; antiSMASH:Cluster_8.15; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_81210A COG:O; EggNog:ENOG410PGF2; InterPro:IPR036249,IPR040079,IPR036282,IPR010987, IPR004045,IPR004046; PFAM:PF13409,PF00043,PF14497,PF13417,PF13410, PF02798; SMCOG1193:glutathione S-transferase; antiSMASH:Cluster_8.15; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0006749 - glutathione metabolic process [Evidence IEA] AKAW2_81211S COG:S; EggNog:ENOG410PRT3; InterPro:IPR005645,IPR029058; PFAM:PF03959; antiSMASH:Cluster_8.15 AKAW2_81212S COG:Q; EggNog:ENOG410PFKE; InterPro:IPR016036,IPR016035,IPR016039,IPR018201, IPR042104,IPR014030,IPR011032,IPR013968,IPR001227, IPR032821,IPR014031,IPR014043,IPR020806,IPR020807, IPR020843,IPR020841,IPR009081,IPR029063,IPR036736, IPR036291; PFAM:PF16197,PF00550,PF00109,PF13561,PF02801, PF00698,PF08659,PF14765,PF00106; SMCOG1021:malonyl CoA-acyl carrier protein transacylase; TransMembrane:1 (o1984-2003i); antiSMASH:Cluster_8.15; go_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein] synthase activity [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_function: GO:0016740 - transferase activity [Evidence IEA]; go_function: GO:0016746 - transferase activity, transferring acyl groups [Evidence IEA]; go_function: GO:0031177 - phosphopantetheine binding [Evidence IEA]; go_process: GO:0006633 - fatty acid biosynthetic process [Evidence IEA] AKAW2_81213A COG:I; EggNog:ENOG410PQB7; InterPro:IPR000873,IPR036736,IPR042099,IPR023213, IPR020845; PFAM:PF00501; SMCOG1002:AMP-dependent synthetase and ligase; antiSMASH:Cluster_8.15 AKAW2_81214S COG:S; EggNog:ENOG410PYGA; InterPro:IPR011057,IPR006913; PFAM:PF04828; antiSMASH:Cluster_8.15; go_function: GO:0016846 - carbon-sulfur lyase activity [Evidence IEA] AKAW2_81215S COG:S; EggNog:ENOG410PUN9; InterPro:IPR036291,IPR008030; PFAM:PF13460,PF05368; SMCOG1199:NmrA family protein; antiSMASH:Cluster_8.15 AKAW2_81216S COG:G; EggNog:ENOG410Q07H; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; SMCOG1005:Drug resistance transporter, EmrB/QacA; TransMembrane:12 (i89-108o128-145i157-176o182-203i215-239o245-266i316- 338o358-382i407-426o432-459i471-494o500-522i); antiSMASH:Cluster_8.15; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_81217S COG:S; EggNog:ENOG410PK7P; InterPro:IPR001077,IPR036388,IPR016461,IPR029063, IPR036390; PFAM:PF00891; SMCOG1042:O-methyltransferase; antiSMASH:Cluster_8.15; go_function: GO:0008168 - methyltransferase activity [Evidence IEA]; go_function: GO:0008171 - O-methyltransferase activity [Evidence IEA] AKAW2_81218A COG:G; EggNog:ENOG410PUJ2; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; SMCOG1106:major facilitator transporter; TransMembrane:11 (o46-64i85-105o111-129i141-162o209-235i282-301o321- 340i361-380o386-406i418-443o455-476i); antiSMASH:Cluster_8.15; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_81219S COG:S; EggNog:ENOG410PQP4; InterPro:IPR029063,IPR013217; PFAM:PF13649,PF08242,PF08241,PF13847; antiSMASH:Cluster_8.15 AKAW2_81220A InterPro:IPR000873,IPR020845,IPR009081,IPR006162, IPR036736,IPR020806,IPR010071,IPR042099,IPR023213, IPR001242; PFAM:PF00501,PF00668,PF00550; SMCOG1002:AMP-dependent synthetase and ligase; TransMembrane:2 (o4104-4122i4143-4163o); antiSMASH:Cluster_8.15; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0031177 - phosphopantetheine binding [Evidence IEA] AKAW2_81221S COG:O; EggNog:ENOG410PQPZ; InterPro:IPR023753,IPR036188; SMCOG1176:alkyl hydroperoxide reductase subunit; antiSMASH:Cluster_8.16; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_81222S COG:G; EggNog:ENOG410QE2U; InterPro:IPR020846,IPR011701,IPR036259; TransMembrane:5 (i38-63o75-92i104-124o130-152i164-191o); antiSMASH:Cluster_8.16; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_81223S COG:G; EggNog:ENOG410QE2U; InterPro:IPR036259,IPR010573; TransMembrane:3 (o15-36i57-76o88-107i); antiSMASH:Cluster_8.16; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_81224S COG:G; EggNog:ENOG410QE2U; InterPro:IPR036259; SMCOG1005:Drug resistance transporter, EmrB/QacA; TransMembrane:5 (o6-26i33-54o60-79i91-112o124-143i); antiSMASH:Cluster_8.16 AKAW2_81225A COG:G; EggNog:ENOG410QDHR; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; SMCOG1106:major facilitator transporter; TransMembrane:8 (i94-112o124-141i153-174o186-208i287-306o318-336i379- 399o411-433i); antiSMASH:Cluster_8.16; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_81226A TransMembrane:2 (o27-46i67-85o); antiSMASH:Cluster_8.16 AKAW2_81227A COG:E; EggNog:ENOG410PVTE; InterPro:IPR036038,IPR043131,IPR043132; antiSMASH:Cluster_8.16; go_function: GO:0003824 - catalytic activity [Evidence IEA] AKAW2_81228S antiSMASH:Cluster_8.16 AKAW2_81229A COG:S; EggNog:ENOG410PX3W; InterPro:IPR036047,IPR032675; antiSMASH:Cluster_8.16; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_81230A COG:T; EggNog:ENOG410PG4N; InterPro:IPR004843,IPR029052,IPR006186; PFAM:PF00149; antiSMASH:Cluster_8.16; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_81231S COG:T; EggNog:ENOG410QDCN; InterPro:IPR029052,IPR031675,IPR037979,IPR006186, IPR004843; PFAM:PF00149,PF16891; go_component: GO:0000164 - protein phosphatase type 1 complex [Evidence IEA]; go_component: GO:0072357 - PTW/PP1 phosphatase complex [Evidence IEA]; go_function: GO:0004722 - protein serine/threonine phosphatase activity [Evidence IEA]; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_81232A COG:S; EggNog:ENOG410PXA4; TransMembrane:6 (o12-32i44-64o84-106i118-144o164-188i200-226o) AKAW2_81233A COG:S; EggNog:ENOG410PR0A; InterPro:IPR036864,IPR001138; PFAM:PF00172; TransMembrane:1 (i236-255o); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_81234A COG:S; EggNog:ENOG410PX1B; InterPro:IPR000868,IPR036380; PFAM:PF00857 AKAW2_81235S COG:G; EggNog:ENOG410PFF2; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; SECRETED:SignalP(1-17); TransMembrane:9 (n2-12c17/18o33-50i57-81o87-107i164-186o206-230i271- 290o296-324i336-357o363-387i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_81237A COG:L; EggNog:ENOG410PQK2; InterPro:IPR012337,IPR002156,IPR036397; PFAM:PF00075; go_function: GO:0003676 - nucleic acid binding [Evidence IEA]; go_function: GO:0004523 - RNA-DNA hybrid ribonuclease activity [Evidence IEA] AKAW2_81240A CAZy:GH15; COG:G; EggNog:ENOG410PK47; InterPro:IPR011613,IPR008928,IPR012341; PFAM:PF00723; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_81242A COG:S; EggNog:ENOG410PM9G; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_81243S COG:G; EggNog:ENOG410PKJH; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690,PF06609; TransMembrane:11 (o35-54i105-125o131-155i167-188o194-214i235-255o261- 283i303-324o336-357i364-385o502-523i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_81244A CAZy:CE10; COG:V; EggNog:ENOG410PPZU; InterPro:IPR029058,IPR013094; MEROPS:MER0043146; PFAM:PF07859; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_81245S COG:S; EggNog:ENOG410PPN3 AKAW2_81246S COG:S; EggNog:ENOG410PXZA AKAW2_81248A COG:Q; EggNog:ENOG410PJIT; InterPro:IPR017871,IPR027417,IPR003593,IPR039421, IPR011527,IPR003439,IPR036640; PFAM:PF00005,PF00664; TransMembrane:11 (i66-89o121-143i194-211o217-237i297-320o332-354i712- 734o754-773i833-853o859-877i936-960o); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA]; go_function: GO:0042626 - ATPase-coupled transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_81249S COG:S; EggNog:ENOG410PRR3; InterPro:IPR036864,IPR001138; PFAM:PF00172; TransMembrane:1 (o515-533i); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_81250S COG:H; EggNog:ENOG410PH96; InterPro:IPR001613,IPR036188,IPR002937; PFAM:PF13450,PF01593; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_81251A COG:O; EggNog:ENOG410PKD0; InterPro:IPR034164,IPR021109,IPR001461,IPR001969, IPR033121; MEROPS:MER0090759; PFAM:PF00026; SECRETED:SignalP(1-20); go_function: GO:0004190 - aspartic-type endopeptidase activity [Evidence IEA]; go_process: GO:0006508 - proteolysis [Evidence IEA] AKAW2_81252S COG:S; EggNog:ENOG410PP4N; InterPro:IPR036864,IPR021858,IPR001138; PFAM:PF00172; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_81254S COG:S; EggNog:ENOG410PR2T AKAW2_81255S InterPro:IPR036236,IPR013087; PFAM:PF00096 AKAW2_81256S InterPro:IPR036236,IPR013087; PFAM:PF00096 AKAW2_81258S COG:S; EggNog:ENOG410PSJS; InterPro:IPR015943,IPR011659; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_81259S COG:S; EggNog:ENOG410PSJS; InterPro:IPR015943,IPR036322; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_81260S COG:U; EggNog:ENOG410PW0W; InterPro:IPR011042,IPR011659; PFAM:PF07676; SECRETED:SignalP(1-18) AKAW2_81264A CAZy:AA3; COG:E; EggNog:ENOG410Q22J; InterPro:IPR012132,IPR036188,IPR027424,IPR000172, IPR007867; PFAM:PF00732,PF05199; SECRETED:SignalP(1-17); go_function: GO:0016614 - oxidoreductase activity, acting on CH-OH group of donors [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_81265A COG:E; EggNog:ENOG410QDM5; InterPro:IPR004841; PFAM:PF13520; TransMembrane:5 (n19-30c38/39o54-81i114-133o145-166i186-205o217-238i); go_component: GO:0016020 - membrane [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_81266A COG:E; EggNog:ENOG410QDM5; InterPro:IPR004840,IPR004841; TransMembrane:5 (i58-80o86-112i124-145o165-187i199-217o); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_process: GO:0006865 - amino acid transport [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_81267A COG:S; EggNog:ENOG410PT24; TransMembrane:1 (o307-328i) AKAW2_81268A COG:S; EggNog:ENOG410PVHY; InterPro:IPR036864,IPR001138; PFAM:PF00172; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_81269S COG:S; EggNog:ENOG410PKXX; InterPro:IPR018750; PFAM:PF10067; TransMembrane:6 (i31-51o85-107i119-137o149-168i180-198o275-294i) AKAW2_81270A CAZy:GH5; COG:G; EggNog:ENOG410PKKN; InterPro:IPR017853,IPR001547; PFAM:PF00150; SECRETED:SignalP(1-21); go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_process: GO:0071704 - organic substance metabolic process [Evidence IEA] AKAW2_81271S COG:G; EggNog:ENOG410Q2KJ; InterPro:IPR005829,IPR005828,IPR003663,IPR036259, IPR020846; PFAM:PF00083,PF07690; TransMembrane:12 (i42-62o98-118i125-144o156-173i185-204o216-238i300- 324o339-360i369-391o406-429i441-463o469-490i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_81272S COG:L; EggNog:ENOG410PQ68; InterPro:IPR036397,IPR013520,IPR012337; go_function: GO:0003676 - nucleic acid binding [Evidence IEA] AKAW2_81273S InterPro:IPR001810,IPR036047; PFAM:PF00646; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_81274S InterPro:IPR001810,IPR036047; PFAM:PF00646; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_81276S COG:S; EggNog:ENOG410PZJ4 AKAW2_81277S COG:Q; EggNog:ENOG410PJ8G; InterPro:IPR002347,IPR036291,IPR020904; PFAM:PF00106,PF13561,PF08659; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_81278A COG:C,H; EggNog:ENOG410PGHD; InterPro:IPR036188,IPR002938; PFAM:PF01494; go_function: GO:0071949 - FAD binding [Evidence IEA] AKAW2_81279S COG:D; EggNog:ENOG410PRNJ; InterPro:IPR001763,IPR036873; PFAM:PF00581 AKAW2_81280A COG:S; EggNog:ENOG410PH5E; InterPro:IPR014063,IPR005025,IPR029039; PFAM:PF03358; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA] AKAW2_81281A COG:S; EggNog:ENOG410PN1Y; InterPro:IPR025714,IPR029063,IPR026669; PFAM:PF13649,PF13489,PF08242,PF08241,PF13847 AKAW2_81282S COG:S; EggNog:ENOG410PNBP; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; TransMembrane:1 (o569-589i); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_81283S COG:G; EggNog:ENOG410Q07H; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i78-102o114-133i145-165o171-196i203-222o234-253i310- 329o349-369i389-408o420-441i453-475o481-504i); antiSMASH:Cluster_8.17; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_81284S COG:Q; EggNog:ENOG410PV61; InterPro:IPR001128,IPR017972,IPR002401,IPR036396; PFAM:PF00067; SMCOG1034:cytochrome P450; antiSMASH:Cluster_8.17; go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]; go_function: GO:0020037 - heme binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_81285A COG:Q; EggNog:ENOG410PKKR; InterPro:IPR017871,IPR027417,IPR003593,IPR011527, IPR003439,IPR036640; PFAM:PF00005,PF00664; SMCOG1000:ABC transporter ATP-binding protein; TransMembrane:18 (o36-54i66-89o101-120i132-153o159-179i276-293o313-333i390- 408o414-436i491-517o537-562i967-987o1007-1033i1040- 1059o1079-1099i1106-1125o1190-1209i1221-1244o); antiSMASH:Cluster_8.17; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA]; go_function: GO:0042626 - ATPase-coupled transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_81286S COG:E; EggNog:ENOG410PVTE; InterPro:IPR036038,IPR005786,IPR001544,IPR043131, IPR043132; PFAM:PF01063; antiSMASH:Cluster_8.17; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0004084 - branched-chain-amino-acid transaminase activity [Evidence IEA]; go_process: GO:0009081 - branched-chain amino acid metabolic process [Evidence IEA] AKAW2_81287S COG:S; EggNog:ENOG410QE8M; InterPro:IPR029069; PFAM:PF13279; antiSMASH:Cluster_8.17 AKAW2_81288S COG:S; EggNog:ENOG410Q014; InterPro:IPR002110,IPR036770,IPR020683; PFAM:PF12796,PF00023,PF13606; antiSMASH:Cluster_8.17; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_81289A COG:S; EggNog:ENOG410PJXJ; InterPro:IPR007568; PFAM:PF04479; TransMembrane:7 (o54-72i79-99o111-132i153-174o194-213i241-259o279-305i); antiSMASH:Cluster_8.17; go_component: GO:0016021 - integral component of membrane [Evidence IEA] AKAW2_81290S InterPro:IPR000873,IPR020845,IPR009081,IPR006162, IPR036736,IPR020806,IPR023213,IPR042099,IPR010071, IPR001242; PFAM:PF00501,PF00550; SMCOG1002:AMP-dependent synthetase and ligase; antiSMASH:Cluster_8.17; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0031177 - phosphopantetheine binding [Evidence IEA] AKAW2_81291A COG:S; EggNog:ENOG410PWIG; InterPro:IPR036864,IPR021858,IPR001138; PFAM:PF00172,PF11951; antiSMASH:Cluster_8.17; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_81292S COG:S; EggNog:ENOG410PX83; TransMembrane:5 (o6-24i31-50o62-82i94-112o132-153i); antiSMASH:Cluster_8.17 AKAW2_81293S COG:I; EggNog:ENOG410PFXA; InterPro:IPR016035,IPR002642; PFAM:PF01735; antiSMASH:Cluster_8.17; go_function: GO:0004620 - phospholipase activity [Evidence IEA]; go_process: GO:0009395 - phospholipid catabolic process [Evidence IEA] AKAW2_81294S COG:F; EggNog:ENOG410Q2NC; InterPro:IPR000845,IPR035994; PFAM:PF01048; antiSMASH:Cluster_8.17; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_process: GO:0009116 - nucleoside metabolic process [Evidence IEA] AKAW2_81295A COG:C; EggNog:ENOG410PK7G; InterPro:IPR043144,IPR036111,IPR043143,IPR003767; PFAM:PF02615; antiSMASH:Cluster_8.17; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_81296A COG:S; EggNog:ENOG410PPIN; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; TransMembrane:2 (i303-323o548-569i); antiSMASH:Cluster_8.17; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_81297A COG:S; EggNog:ENOG410PX9Z; InterPro:IPR011008,IPR013097; PFAM:PF07876; antiSMASH:Cluster_8.17 AKAW2_81298A COG:Q; EggNog:ENOG410PUYC; InterPro:IPR036291,IPR002347,IPR020904; PFAM:PF00106,PF13561; SMCOG1001:short-chain dehydrogenase/reductase SDR; antiSMASH:Cluster_8.17; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_81299S COG:S; EggNog:ENOG410PSYS; InterPro:IPR037401,IPR032710; PFAM:PF13577; antiSMASH:Cluster_8.17 AKAW2_81300A COG:S; EggNog:ENOG410PMMF; InterPro:IPR036250,IPR009100; antiSMASH:Cluster_8.17; go_function: GO:0016627 - oxidoreductase activity, acting on the CH-CH group of donors [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_81301S COG:S; EggNog:ENOG410PY9H; InterPro:IPR025568,IPR025951; PFAM:PF14232,PF14231 AKAW2_81302A COG:E; EggNog:ENOG410PV03; InterPro:IPR002293; PFAM:PF00324,PF13520; TransMembrane:12 (i56-76o96-117i138-166o186-205i212-232o252-275i287- 313o340-360i392-412o418-442i463-481o493-513i); go_component: GO:0016020 - membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_81303A COG:S; EggNog:ENOG410PMC0; InterPro:IPR013785,IPR004136; PFAM:PF03060; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0018580 - nitronate monooxygenase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_81305S COG:S; EggNog:ENOG410PITQ; InterPro:IPR000073,IPR029058; MEROPS:MER0017243; PFAM:PF12697; TransMembrane:1 (i86-103o) AKAW2_81306A COG:S; EggNog:ENOG410PYIX; InterPro:IPR036069,IPR015867 AKAW2_81307A COG:G; EggNog:ENOG410PW31; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i58-82o94-114i126-145o151-176i188-209o215-234i282- 307o327-351i380-401o407-428i440-465o471-492i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_81308A COG:S; EggNog:ENOG410PRB8; InterPro:IPR005247,IPR036610,IPR008914; PFAM:PF01161 AKAW2_81312S COG:U; EggNog:ENOG410PV75; InterPro:IPR036188,IPR002938; PFAM:PF01494; TransMembrane:4 (o6-27i616-634o646-666i687-705o); go_function: GO:0071949 - FAD binding [Evidence IEA] AKAW2_81313A COG:M; EggNog:ENOG410PG00; InterPro:IPR002110,IPR020683,IPR036770; PFAM:PF00023,PF12796; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_81314A COG:S; EggNog:ENOG410PWFA; InterPro:IPR000845,IPR035994; PFAM:PF01048; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_process: GO:0009116 - nucleoside metabolic process [Evidence IEA] AKAW2_81315A COG:S; EggNog:ENOG410PWA8; InterPro:IPR036291,IPR006694; PFAM:PF04116; TransMembrane:4 (o6-28i68-92o104-124i354-374o); go_function: GO:0005506 - iron ion binding [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0008610 - lipid biosynthetic process [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_81316A COG:Q; EggNog:ENOG410PG6M; InterPro:IPR034001,IPR043926,IPR027417,IPR003593, IPR010929,IPR017871,IPR029481,IPR003439,IPR013525, IPR034003; PFAM:PF01061,PF00005,PF06422,PF14510; TransMembrane:12 (i525-548o560-582i594-615o635-656i668-687o774-794i1191- 1212o1224-1245i1266-1292o1312-1334i1346-1370o1463-1483i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA]; go_function: GO:0042626 - ATPase-coupled transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_81317S COG:S; EggNog:ENOG410Q1SV; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_81318A COG:Q; EggNog:ENOG410PVT9; InterPro:IPR017871,IPR027417,IPR003593,IPR011527, IPR003439,IPR036640; PFAM:PF00005,PF00664; TransMembrane:6 (n38-45c50/51o66-90i466-486o498-521i572-595o601-621i685- 705o); go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016887 - ATPase activity [Evidence IEA]; go_function: GO:0042626 - ATPase-coupled transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_81319A COG:S; EggNog:ENOG410PRWR; InterPro:IPR021765; PFAM:PF11807; TransMembrane:1 (i7-27o); go_process: GO:0043386 - mycotoxin biosynthetic process [Evidence IEA] AKAW2_81320A COG:S; EggNog:ENOG410PPF9; InterPro:IPR021765; PFAM:PF11807; TransMembrane:1 (i56-79o); go_process: GO:0043386 - mycotoxin biosynthetic process [Evidence IEA] AKAW2_81321S SECRETED:SignalP(1-21) AKAW2_81322A COG:E; EggNog:ENOG410PFA4; InterPro:IPR004841; PFAM:PF13520,PF00324; TransMembrane:5 (o27-49i56-76o82-102i177-196o301-322i); go_component: GO:0016020 - membrane [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_81323A COG:E; EggNog:ENOG410PFA4 AKAW2_81324A CAZy:GT32; COG:M; EggNog:ENOG410PKZA; InterPro:IPR029044,IPR007577,IPR039367; PFAM:PF04488; TransMembrane:1 (i141-159o); go_function: GO:0000009 - alpha-1,6-mannosyltransferase activity [Evidence IEA] AKAW2_81325S COG:S; EggNog:ENOG410PJTD; InterPro:IPR002656; PFAM:PF01757; TransMembrane:8 (i112-133o153-174i223-241o253-278i290-312o347-366i378- 397o435-455i); go_function: GO:0016747 - transferase activity, transferring acyl groups other than amino-acyl groups [Evidence IEA] AKAW2_81326S COG:S; EggNog:ENOG410PJ4N; antiSMASH:Cluster_8.18 AKAW2_81327A COG:S; EggNog:ENOG410PHJ1; InterPro:IPR029063,IPR013216; PFAM:PF13649,PF13489,PF08241,PF08242,PF13847; SMCOG1089:methyltransferase; antiSMASH:Cluster_8.18; go_function: GO:0008168 - methyltransferase activity [Evidence IEA] AKAW2_81328S antiSMASH:Cluster_8.18 AKAW2_81329S COG:Q; EggNog:ENOG410PPBW; InterPro:IPR037455,IPR007310,IPR022770; PFAM:PF06276; antiSMASH:Cluster_8.18; go_process: GO:0019290 - siderophore biosynthetic process [Evidence IEA] AKAW2_81330S COG:S; EggNog:ENOG410PM15; SECRETED:SignalP(1-18); antiSMASH:Cluster_8.18 AKAW2_81331A COG:C; EggNog:ENOG410PM0S; InterPro:IPR013785,IPR004136; antiSMASH:Cluster_8.18; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0018580 - nitronate monooxygenase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_81332A COG:S; EggNog:ENOG410PQSC; InterPro:IPR014710,IPR011051,IPR013096; PFAM:PF07883,PF00190 AKAW2_81333A COG:K; EggNog:ENOG410PZEQ; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_81334A COG:G; EggNog:ENOG410Q1TP; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:12 (i74-95o107-129i141-159o165-188i200-223o229-251i307- 326o346-363i384-405o411-436i443-468o480-499i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_81335S COG:G; EggNog:ENOG410QDAP; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:11 (i49-74o94-116i123-142o154-175i182-208o214-234i272- 294o337-355i367-386o406-426i438-459o); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_81336S COG:J; EggNog:ENOG410PHQF; InterPro:IPR023631,IPR036928,IPR000120; SECRETED:SignalP(1-20); go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_81337S COG:E,O; EggNog:ENOG410PHV7; InterPro:IPR018202,IPR001563,IPR029058; MEROPS:MER0003541; PFAM:PF00450; SECRETED:SignalP(1-19); go_function: GO:0004185 - serine-type carboxypeptidase activity [Evidence IEA]; go_process: GO:0006508 - proteolysis [Evidence IEA] AKAW2_81338S COG:S; EggNog:ENOG410PMZV; InterPro:IPR036851,IPR000028; PFAM:PF01328; go_function: GO:0004601 - peroxidase activity [Evidence IEA] AKAW2_81339A COG:S; EggNog:ENOG410PJ7E; InterPro:IPR000073,IPR029058; MEROPS:MER0209971; PFAM:PF12697 AKAW2_81340S TransMembrane:1 (o12-30i) AKAW2_81341S COG:S; EggNog:ENOG410Q9FB; InterPro:IPR037401,IPR011944,IPR032710; PFAM:PF02136,PF13474,PF14534,PF13577,PF12680 AKAW2_81342A COG:S; EggNog:ENOG410PN0M; InterPro:IPR040632,IPR027417; PFAM:PF17784; TransMembrane:1 (o259-280i) AKAW2_81343A COG:Q; EggNog:ENOG410PIGG; InterPro:IPR013154,IPR013149,IPR002328,IPR036291, IPR011032; PFAM:PF00107,PF08240; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_81344A COG:G; EggNog:ENOG410PHVM; InterPro:IPR005829,IPR005828,IPR003663,IPR036259, IPR020846; PFAM:PF00083; TransMembrane:7 (n9-20c25/26o61-83i150-169o181-202i342-362o382-403i415- 437o443-464i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_81345S COG:S; EggNog:ENOG410PI00; InterPro:IPR036864,IPR021858,IPR001138; PFAM:PF00172; TransMembrane:1 (o485-507i); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_81346A COG:G; EggNog:ENOG410PJXV; InterPro:IPR011042,IPR013658 AKAW2_81347A COG:G; EggNog:ENOG410PWP3 AKAW2_81348S COG:G; EggNog:ENOG410PIGI; InterPro:IPR000771,IPR013785; PFAM:PF01116; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_function: GO:0016832 - aldehyde-lyase activity [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_81349A COG:Q; EggNog:ENOG410PJ9Z; InterPro:IPR036291,IPR002347; PFAM:PF08659,PF00106,PF13561; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_81350S COG:Q; EggNog:ENOG410PVI4; InterPro:IPR002347,IPR036291,IPR020904; PFAM:PF00106,PF13561,PF08659; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_81351A COG:C; EggNog:ENOG410PMDV; InterPro:IPR018170,IPR020471,IPR036812,IPR023210; PFAM:PF00248; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_81352A COG:S; EggNog:ENOG410Q2HD; TransMembrane:7 (o34-55i67-91o111-132i144-166o195-215i227-246o266-290i) AKAW2_81353A COG:S; EggNog:ENOG410PPDK; SECRETED:SignalP(1-16) AKAW2_81354A COG:S; EggNog:ENOG410Q1F3; InterPro:IPR011990; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_81355A COG:S; EggNog:ENOG410Q1F3; InterPro:IPR027417 AKAW2_81356S COG:Q; EggNog:ENOG410PS4W; InterPro:IPR036291,IPR002347; PFAM:PF08659,PF00106,PF13561; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_81357S COG:E,O; EggNog:ENOG410Q1SM; InterPro:IPR018202,IPR001563,IPR029058; MEROPS:MER0002512; PFAM:PF00450; SECRETED:SignalP(1-23); go_function: GO:0004185 - serine-type carboxypeptidase activity [Evidence IEA]; go_process: GO:0006508 - proteolysis [Evidence IEA] AKAW2_81358S COG:E; EggNog:ENOG410QDDF; InterPro:IPR000192,IPR015424,IPR015421; go_function: GO:0003824 - catalytic activity [Evidence IEA] AKAW2_81359A COG:Z; EggNog:ENOG410PVJA; InterPro:IPR019821,IPR036961,IPR027417,IPR027640, IPR001752; PFAM:PF16796,PF00225; go_function: GO:0003777 - microtubule motor activity [Evidence IEA]; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0008017 - microtubule binding [Evidence IEA]; go_process: GO:0007018 - microtubule-based movement [Evidence IEA] AKAW2_81360A COG:M; EggNog:ENOG410Q18J; InterPro:IPR002110,IPR027417,IPR007111,IPR036770, IPR020683; PFAM:PF13857,PF05729,PF12796,PF00023,PF13637, PF13606; go_function: GO:0005515 - protein binding [Evidence IEA] AKAW2_81361A COG:F; EggNog:ENOG410PMHQ; InterPro:IPR000845,IPR035994; PFAM:PF01048; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_process: GO:0009116 - nucleoside metabolic process [Evidence IEA] AKAW2_81362A COG:E; EggNog:ENOG410PV5E; InterPro:IPR008794; PFAM:PF05544 AKAW2_81363A COG:S; EggNog:ENOG410PIDI; InterPro:IPR036412,IPR041492,IPR006439,IPR023214; PFAM:PF13419; go_function: GO:0016787 - hydrolase activity [Evidence IEA] AKAW2_81364S COG:S; EggNog:ENOG410PXGI AKAW2_81365S COG:S; EggNog:ENOG410PXGI AKAW2_81366A COG:S; EggNog:ENOG410PUQG; InterPro:IPR012047,IPR007506,IPR002840; PFAM:PF01989,PF04412 AKAW2_81367S COG:C; EggNog:ENOG410PMBI; InterPro:IPR001155,IPR013785; PFAM:PF00724; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0010181 - FMN binding [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_81368S COG:C; EggNog:ENOG410PMBI; InterPro:IPR001155,IPR013785; go_function: GO:0003824 - catalytic activity [Evidence IEA]; go_function: GO:0010181 - FMN binding [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_81369S COG:S; EggNog:ENOG410PR61; InterPro:IPR018466; PFAM:PF10342; SECRETED:SignalP(1-16) AKAW2_81370A COG:Q; EggNog:ENOG410PFUH; InterPro:IPR013154,IPR013149,IPR002328,IPR036291, IPR011032,IPR020843; PFAM:PF00107,PF08240; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_81371A COG:E; EggNog:ENOG410PKA9; InterPro:IPR011701,IPR036259; PFAM:PF07690; TransMembrane:9 (o71-92i99-119o125-142i163-185o197-216i254-274o286- 307i319-343o349-368i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_81372A COG:S; EggNog:ENOG410PISU; InterPro:IPR000073,IPR029058; PFAM:PF12697,PF00561; SECRETED:SignalP(1-33) AKAW2_81373S COG:M; EggNog:ENOG410PNC5; InterPro:IPR039516,IPR024078,IPR003737; PFAM:PF02585; TransMembrane:1 (i20-47o); go_function: GO:0000225 - N-acetylglucosaminylphosphatidylinositol deacetylase activity [Evidence IEA]; go_process: GO:0006506 - GPI anchor biosynthetic process [Evidence IEA] AKAW2_81374A CAZy:GT32; COG:G; EggNog:ENOG410PKKB; InterPro:IPR029044,IPR007577; PFAM:PF04488; TransMembrane:1 (n8-18c22/23o296-316i) AKAW2_81375S COG:M; EggNog:ENOG410PUFY; InterPro:IPR039367; go_function: GO:0000009 - alpha-1,6-mannosyltransferase activity [Evidence IEA] AKAW2_81376A CAZy:GH2; COG:G; EggNog:ENOG410PMBT; InterPro:IPR006103,IPR006102,IPR006104,IPR036156, IPR008979,IPR017853,IPR013783; PFAM:PF02837; go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_81377A COG:S; EggNog:ENOG410PNYD; TransMembrane:7 (o12-32i44-65o85-108i120-141o174-194i206-226o246-268i) AKAW2_81378A CAZy:GH28; COG:G; EggNog:ENOG410PMNA; InterPro:IPR000743,IPR012334,IPR006626,IPR011050; PFAM:PF00295; SECRETED:SignalP(1-19); go_function: GO:0004650 - polygalacturonase activity [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_81379A COG:S; EggNog:ENOG410PVME; InterPro:IPR041492,IPR027417,IPR023198,IPR036412, IPR023214; PFAM:PF12710,PF00702,PF13242,PF13419 AKAW2_81380S COG:S; EggNog:ENOG410PHWY; InterPro:IPR039535 AKAW2_81381S COG:S; EggNog:ENOG410PHWY; InterPro:IPR039535; PFAM:PF14269 AKAW2_81382A COG:S; EggNog:ENOG410PKVM; InterPro:IPR036864,IPR007219,IPR001138; PFAM:PF00172,PF04082; TransMembrane:1 (o478-497i); go_function: GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific [Evidence IEA]; go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA]; go_process: GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA] AKAW2_81384A COG:O; EggNog:ENOG410PJZS; InterPro:IPR005338,IPR043129; PFAM:PF03702; go_function: GO:0005524 - ATP binding [Evidence IEA]; go_function: GO:0016773 - phosphotransferase activity, alcohol group as acceptor [Evidence IEA]; go_process: GO:0006040 - amino sugar metabolic process [Evidence IEA]; go_process: GO:0009254 - peptidoglycan turnover [Evidence IEA] AKAW2_81383S COG:G; EggNog:ENOG410PGM3; InterPro:IPR005829,IPR005828,IPR003663,IPR036259, IPR020846; PFAM:PF00083,PF07690; TransMembrane:11 (o67-86i93-112o118-141i153-173o185-205i282-304o316- 336i348-367o379-407i419-443o449-468i); go_component: GO:0016020 - membrane [Evidence IEA]; go_component: GO:0016021 - integral component of membrane [Evidence IEA]; go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_81385S COG:G; EggNog:ENOG410QDHD; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:8 (i39-57o84-106i113-132o138-161i173-195o207-229i272- 289o325-343i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_81386S CAZy:GH11; COG:G; EggNog:ENOG410PPXP; InterPro:IPR001137,IPR013319,IPR033119,IPR033123, IPR018208,IPR013320; PFAM:PF00457; SECRETED:SignalP(1-16); go_function: GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]; go_process: GO:0005975 - carbohydrate metabolic process [Evidence IEA] AKAW2_81387S COG:S; EggNog:ENOG410Q2VU; InterPro:IPR007219; TransMembrane:2 (o131-151i172-192o); go_function: GO:0003677 - DNA binding [Evidence IEA]; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_process: GO:0006351 - transcription, DNA-templated [Evidence IEA] AKAW2_81388S InterPro:IPR037401,IPR032710; PFAM:PF13577 AKAW2_81389A COG:S; EggNog:ENOG410PFDP; InterPro:IPR036291 AKAW2_81390A CAZy:AA3; COG:E; EggNog:ENOG410PI4D; InterPro:IPR007867,IPR012132,IPR000172,IPR036188; PFAM:PF05199; SECRETED:SignalP(1-18); go_function: GO:0016614 - oxidoreductase activity, acting on CH-OH group of donors [Evidence IEA]; go_function: GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_81391A COG:S; EggNog:ENOG410PIUV; TransMembrane:2 (i26-46o66-85i) AKAW2_81392S COG:S; EggNog:ENOG410PKRB; InterPro:IPR036851,IPR000028; PFAM:PF01328; SECRETED:SignalP(1-21); go_function: GO:0004601 - peroxidase activity [Evidence IEA] AKAW2_81393A COG:K; EggNog:ENOG410PPT4; InterPro:IPR000182,IPR016181; PFAM:PF13673,PF00583; go_function: GO:0008080 - N-acetyltransferase activity [Evidence IEA] AKAW2_81394A COG:Q; EggNog:ENOG410PHHZ; InterPro:IPR013154,IPR013149,IPR036291,IPR011032, IPR020843; PFAM:PF00107,PF08240; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_81395S COG:Q; EggNog:ENOG410PWPD; InterPro:IPR036291,IPR002347; PFAM:PF00106; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_81396S COG:Q; EggNog:ENOG410PHHZ; InterPro:IPR036291,IPR020843,IPR013154,IPR011032; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_81397S COG:J; EggNog:ENOG410PPG4; InterPro:IPR036249,IPR040079,IPR036282,IPR010987, IPR004045,IPR004046; PFAM:PF00043,PF13417,PF02798; go_function: GO:0005515 - protein binding [Evidence IEA]; go_process: GO:0006749 - glutathione metabolic process [Evidence IEA] AKAW2_81398S COG:S; EggNog:ENOG410PX84; InterPro:IPR036291,IPR016040; PFAM:PF13460,PF05368 AKAW2_81399S COG:S; EggNog:ENOG410PQBQ; InterPro:IPR021833; PFAM:PF11905 AKAW2_81400A COG:G; EggNog:ENOG410PFTW; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690,PF00083; SECRETED:SignalP(1-21); TransMembrane:12 (i68-87o107-127i134-154o160-182i194-216o228-252i300- 319o339-359i380-399o405-429i436-461o473-492i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_81401S COG:C; EggNog:ENOG410PG0V; InterPro:IPR023210,IPR036812; PFAM:PF00248 AKAW2_81402S COG:S; EggNog:ENOG410PRCU; InterPro:IPR021833; PFAM:PF11905 AKAW2_81403A COG:Q; EggNog:ENOG410PJ3Q; InterPro:IPR013154,IPR013149,IPR002328,IPR036291, IPR011032,IPR029752,IPR020843; PFAM:PF00107,PF08240,PF13602; go_function: GO:0008270 - zinc ion binding [Evidence IEA]; go_function: GO:0016491 - oxidoreductase activity [Evidence IEA]; go_process: GO:0055114 - oxidation-reduction process [Evidence IEA] AKAW2_81404A COG:G; EggNog:ENOG410QEI1; InterPro:IPR020846,IPR011701,IPR036259; PFAM:PF07690; TransMembrane:10 (i12-34o40-64i76-99o105-129i150-171o183-204i216-235o241- 265i277-298o304-323i); go_function: GO:0022857 - transmembrane transporter activity [Evidence IEA]; go_process: GO:0055085 - transmembrane transport [Evidence IEA] AKAW2_81405A InterPro:IPR002110,IPR036770,IPR020683; PFAM:PF00023,PF12796; go_function: GO:0005515 - protein binding [Evidence IEA] EJ508_mgp15 stop codon not determined EJ508_mgp14 stop codon not determined EJ508_mgp08 start codon not determined