-- dump date 20140618_205145 -- class Genbank::CDS -- table cds -- table main -- field 1 id -- field 2 GI -- field 3 GeneID -- field 4 chrom_position -- field 5 chromosome -- field 6 codon_start -- field 7 contig -- field 8 description -- field 9 end_pos -- field 10 gene -- field 11 gene_id -- field 12 name -- field 13 organism -- field 14 product -- field 15 protein_id -- field 16 start_pos -- field 17 strand -- field 18 taxid -- field 19 type -- header -- id GI GeneID chrom_position chromosome codon_start contig description end_pos gene gene_id name organism product protein_id start_pos strand taxid type YP_003915161.1 308151710 9777833 86..532 1 NC_014548.1 2 transmembrane helices predicted by TMHMM2.0; hypothetical protein 532 9777833 AARI_pII00010 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915161.1 86 D 861360 CDS YP_003915162.1 308151711 9777821 complement(676..1659) 1 NC_014548.1 hypothetical protein 1659 9777821 AARI_pII00020 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915162.1 676 R 861360 CDS YP_003915163.1 308151712 9777822 complement(2057..2260) 1 NC_014548.1 hypothetical protein 2260 9777822 AARI_pII00030 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915163.1 2057 R 861360 CDS YP_003915164.1 308151713 9777823 2372..2518 1 NC_014548.1 hypothetical protein 2518 9777823 AARI_pII00040 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915164.1 2372 D 861360 CDS YP_003915165.1 308151714 9777824 complement(2632..2946) 1 NC_014548.1 identified by match to protein family PF03551; PadR-like family transcriptional regulator 2946 9777824 AARI_pII00050 Arthrobacter arilaitensis Re117 PadR-like family transcriptional regulator YP_003915165.1 2632 R 861360 CDS YP_003915166.1 308151715 9777825 complement(2997..3743) 1 NC_014548.1 identified by match to protein family PF03432: Relaxase/Mobilisation nuclease domain. Relaxases/mobilisation proteins are required for the horizontal transfer of genetic information contained on plasmids that occurs during bacterial conjugation; mobilisation protein 3743 9777825 AARI_pII00060 Arthrobacter arilaitensis Re117 mobilisation protein YP_003915166.1 2997 R 861360 CDS YP_003915167.1 308151716 9777826 complement(3740..4222) 1 NC_014548.1 identified by match to protein family PF05713: bacterial mobilisation protein (MobC). This family consists of several bacterial MobC-like, mobilisation proteins. MobC proteins belong to the group of relaxases. Together with MobA and MobB they bind to a single cis-active site of a mobilising plasmid, the origin of transfer (oriT) region; mobilisation protein 4222 9777826 AARI_pII00070 Arthrobacter arilaitensis Re117 mobilisation protein YP_003915167.1 3740 R 861360 CDS YP_003915168.1 308151717 9777827 4384..4587 1 NC_014548.1 hypothetical protein 4587 9777827 AARI_pII00080 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915168.1 4384 D 861360 CDS YP_003915169.1 308151718 9777828 4775..5320 1 NC_014548.1 signal peptide predicted by SignalP 3.0 HMM (probability: 1.000) with cleavage site probability 0.621 between position 22 and 23. 2 transmembrane helices predicted by TMHMM2.0 after the signal peptide; hypothetical protein 5320 9777828 AARI_pII00090 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915169.1 4775 D 861360 CDS YP_003915170.1 308151719 9777829 5450..5713 1 NC_014548.1 signal peptide predicted by SignalP 3.0 HMM (probability: 0.879) with cleavage site probability 0.323 between position 19 and 20. 2 transmembrane helices predicted by TMHMM2.0 after the signal peptide; hypothetical protein 5713 9777829 AARI_pII00100 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915170.1 5450 D 861360 CDS YP_003915171.1 308151720 9777830 6483..7031 1 NC_014548.1 hypothetical protein 7031 9777830 AARI_pII00110 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915171.1 6483 D 861360 CDS YP_003915172.1 308151721 9777831 complement(7028..7726) 1 NC_014548.1 match to PF00239. Possibly involved in site-specific recombination of DNA; putative resolvase 7726 9777831 AARI_pII00120 Arthrobacter arilaitensis Re117 putative resolvase YP_003915172.1 7028 R 861360 CDS YP_003915173.1 308151722 9777832 7842..8390 1 NC_014548.1 signal peptide predicted by SignalP 3.0 HMM (probability: 0.983) with cleavage site probability 0.615 between position 21 and 22; hypothetical protein 8390 9777832 AARI_pII00130 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915173.1 7842 D 861360 CDS YP_003915174.1 308171844 9795859 128..508 1 NC_014549.1 identified by match to PF00436. The Escherichia coli single-strand binding protein binds tightly to single-stranded DNA (ss-DNA) and plays an important role in DNA replication, recombination and repair. Closely related variants of SSB are encoded in the genome of a variety of large self-transmissible plasmids; single-stranded DNA-binding protein 508 9795859 AARI_pI00010 Arthrobacter arilaitensis Re117 single-stranded DNA-binding protein YP_003915174.1 128 D 861360 CDS YP_003915175.1 308171845 9795830 1392..1793 1 NC_014549.1 similar to protein SP:Q9X550 (Corynebacterium glutamicum plasmid R-plasmid pAG1). Signal peptide predicted by SignalP 3.0 HMM (probability: 1.000) with cleavage site probability 0.700 between position 26 and 27; hypothetical protein 1793 9795830 AARI_pI00030 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915175.1 1392 D 861360 CDS YP_003915176.1 308171846 9795855 1797..2246 1 NC_014549.1 similar to protein SP:Q9X549 (Corynebacterium glutamicum plasmid R-plasmid pAG1). Match to PS51257: prokaryotic membrane lipoprotein lipid attachment site profile; hypothetical protein 2246 9795855 AARI_pI00040 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915176.1 1797 D 861360 CDS YP_003915177.1 308171847 9795838 2243..2995 1 NC_014549.1 similar to protein SP:Q9X548 (Corynebacterium glutamicum plasmid R-plasmid pAG1); hypothetical protein 2995 9795838 AARI_pI00050 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915177.1 2243 D 861360 CDS YP_003915178.1 308171848 9795820 3031..3249 1 NC_014549.1 match to PF00376: MerR family regulatory protein; putative DNA-binding protein 3249 9795820 AARI_pI00060 Arthrobacter arilaitensis Re117 putative DNA-binding protein YP_003915178.1 3031 D 861360 CDS YP_003915179.1 308171849 9795834 complement(3252..4565) 1 NC_014549.1 identified by match to protein family PF00817. In Escherichia coli, the gene products of the umuDC operon play important roles in the ability to tolerate damage to its DNA; UmuC-like protein 4565 9795834 AARI_pI00070 Arthrobacter arilaitensis Re117 UmuC-like protein YP_003915179.1 3252 R 861360 CDS YP_003915180.1 308171850 9795864 complement(4547..4978) 1 NC_014549.1 in Escherichia coli, the gene products of the umuDC operon play important roles in the ability to tolerate damage to its DNA; UmuD-like protein 4978 9795864 AARI_pI00080 Arthrobacter arilaitensis Re117 UmuD-like protein YP_003915180.1 4547 R 861360 CDS YP_003915181.1 308171851 9795861 complement(7258..10341) 1 NC_014549.1 type I restriction endonucleases are components of prokaryotic DNA restriction-modification mechanisms that protects the organism against invading foreign DNA. They have three different subunits: subunits - M (modification), S (specificity) and R (restriction) - that form multifunctional enzymes with restriction (EC:3.1.21.3), methylase (EC:2.1.1.72) and ATPase activities. The S subunit is required for both restriction and modification and is responsible for recognition of the DNA sequence specific for the system. The M subunit is necessary for modification, and the R subunit is required for restriction. They recognize asymmetric DNA sequences split into two domains of specific sequence, one 3-4 bp long and another 4-5 bp long, separated by a nonspecific spacer 6-8 bp in length. Cleavage occurs a considerable distance from the recognition sites, rarely less than 400 bp away and up to 7000 bp away. Adenosyl residues are methylated, one on each strand of the recognition sequence; type I restriction-modification system restriction subunit 10341 hsdR 9795861 hsdR Arthrobacter arilaitensis Re117 type I restriction-modification system restriction subunit YP_003915181.1 7258 R 861360 CDS YP_003915182.1 308171852 9795821 complement(10328..11677) 1 NC_014549.1 type I restriction endonucleases are components of prokaryotic DNA restriction-modification mechanisms that protects the organism against invading foreign DNA. They have three different subunits: subunits - M (modification), S (specificity) and R (restriction) - that form multifunctional enzymes with restriction (EC:3.1.21.3), methylase (EC:2.1.1.72) and ATPase activities. The S subunit is required for both restriction and modification and is responsible for recognition of the DNA sequence specific for the system. The M subunit is necessary for modification, and the R subunit is required for restriction. They recognize asymmetric DNA sequences split into two domains of specific sequence, one 3-4 bp long and another 4-5 bp long, separated by a nonspecific spacer 6-8 bp in length. Cleavage occurs a considerable distance from the recognition sites, rarely less than 400 bp away and up to 7000 bp away. Adenosyl residues are methylated, one on each strand of the recognition sequence; type I restriction-modification system specificity subunit 11677 hsdS 9795821 hsdS Arthrobacter arilaitensis Re117 type I restriction-modification system specificity subunit YP_003915182.1 10328 R 861360 CDS YP_003915183.1 308171853 9795840 complement(11674..13635) 1 NC_014549.1 type I restriction endonucleases are components of prokaryotic DNA restriction-modification mechanisms that protects the organism against invading foreign DNA. They have three different subunits: subunits - M (modification), S (specificity) and R (restriction) - that form multifunctional enzymes with restriction (EC:3.1.21.3), methylase (EC:2.1.1.72) and ATPase activities. The S subunit is required for both restriction and modification and is responsible for recognition of the DNA sequence specific for the system. The M subunit is necessary for modification, and the R subunit is required for restriction. They recognize asymmetric DNA sequences split into two domains of specific sequence, one 3-4 bp long and another 4-5 bp long, separated by a nonspecific spacer 6-8 bp in length. Cleavage occurs a considerable distance from the recognition sites, rarely less than 400 bp away and up to 7000 bp away. Adenosyl residues are methylated, one on each strand of the recognition sequence; type I restriction-modification system modification subunit 13635 hsdM 9795840 hsdM Arthrobacter arilaitensis Re117 type I restriction-modification system modification subunit YP_003915183.1 11674 R 861360 CDS YP_003915184.1 308171854 9795853 14835..16142 1 NC_014549.1 transposase of ISAar19, ISL3 family 16142 9795853 AARI_pI00460 Arthrobacter arilaitensis Re117 transposase of ISAar19, ISL3 family YP_003915184.1 14835 D 861360 CDS YP_003915185.1 308171855 9795832 16567..16863 1 NC_014549.1 transposase of ISAar4, IS3 family, IS3 group, orfA 16863 9795832 AARI_pI00470 Arthrobacter arilaitensis Re117 transposase of ISAar4, IS3 family, IS3 group, orfA YP_003915185.1 16567 D 861360 CDS YP_003915186.1 308171856 9795827 16863..17753 1 NC_014549.1 transposase of ISAar4, IS3 family, IS3 group, orfB 17753 9795827 AARI_pI00480 Arthrobacter arilaitensis Re117 transposase of ISAar4, IS3 family, IS3 group, orfB YP_003915186.1 16863 D 861360 CDS YP_003915187.1 308171857 9795817 complement(20225..20818) 1 NC_014549.1 match to PF00239. Possibly involved in site-specific recombination of DNA; putative resolvase 20818 9795817 AARI_pI00120 Arthrobacter arilaitensis Re117 putative resolvase YP_003915187.1 20225 R 861360 CDS YP_003915188.1 308171858 9795818 complement(21002..22309) 1 NC_014549.1 transposase of ISAar19, ISL3 family 22309 9795818 AARI_pI00500 Arthrobacter arilaitensis Re117 transposase of ISAar19, ISL3 family YP_003915188.1 21002 R 861360 CDS YP_003915189.1 308171859 9795822 complement(22488..22901) 1 NC_014549.1 hypothetical protein 22901 9795822 AARI_pI00130 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915189.1 22488 R 861360 CDS YP_003915190.1 308171860 9795856 complement(23011..23637) 1 NC_014549.1 hypothetical protein 23637 9795856 AARI_pI00140 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915190.1 23011 R 861360 CDS YP_003915191.1 308171861 9795857 complement(23639..24709) 1 NC_014549.1 hypothetical protein 24709 9795857 AARI_pI00150 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915191.1 23639 R 861360 CDS YP_003915192.1 308171862 9795851 24962..25207 1 NC_014549.1 hypothetical protein 25207 9795851 AARI_pI00160 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915192.1 24962 D 861360 CDS YP_003915193.1 308171863 9795829 25204..26022 1 NC_014549.1 identified by match to PF02661: Fic protein family. cAMP may be a regulation factor in cell division of some bacteria. The Fic (filamentation induced by cAMP) protein is involved in the synthesis of PAB or folate. It would appear that the Fic protein and cAMP are involved in a regulatory mechanism of cell division via folate metabolism and in these organisms cell division could be controlled by coordination of cAMP, Fic and Fts proteins; Fic family protein 26022 fic 9795829 fic Arthrobacter arilaitensis Re117 Fic family protein YP_003915193.1 25204 D 861360 CDS YP_003915194.1 308171864 9795828 26019..26693 1 NC_014549.1 match to PF00239 and PF02796. Possibly involved in site-specific recombination of DNA; putative resolvase 26693 9795828 AARI_pI00180 Arthrobacter arilaitensis Re117 putative resolvase YP_003915194.1 26019 D 861360 CDS YP_003915195.1 308171865 9795850 complement(26990..27409) 1 NC_014549.1 hypothetical protein 27409 9795850 AARI_pI00190 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915195.1 26990 R 861360 CDS YP_003915196.1 308171866 9795825 27639..28040 1 NC_014549.1 identified by match to protein family PF05713: bacterial mobilisation protein (MobC). This family consists of several bacterial MobC-like, mobilisation proteins. MobC proteins belong to the group of relaxases. Together with MobA and MobB they bind to a single cis-active site of a mobilising plasmid, the origin of transfer (oriT) region; mobilisation protein 28040 9795825 AARI_pI00200 Arthrobacter arilaitensis Re117 mobilisation protein YP_003915196.1 27639 D 861360 CDS YP_003915197.1 308171867 9795846 28037..29746 1 NC_014549.1 identified by match to protein family PF03432: Relaxase/Mobilisation nuclease domain. Relaxases/mobilisation proteins are required for the horizontal transfer of genetic information contained on plasmids that occurs during bacterial conjugation; mobilisation protein 29746 9795846 AARI_pI00210 Arthrobacter arilaitensis Re117 mobilisation protein YP_003915197.1 28037 D 861360 CDS YP_003915198.1 308171868 9795836 29762..30622 1 NC_014549.1 hypothetical protein 30622 9795836 AARI_pI00220 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915198.1 29762 D 861360 CDS YP_003915199.1 308171869 9795839 complement(31305..31667) 1 NC_014549.1 3 transmembrane helices predicted by TMHMM2.0; hypothetical protein 31667 9795839 AARI_pI00230 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915199.1 31305 R 861360 CDS YP_003915200.1 308171870 9795844 complement(31702..32454) 1 NC_014549.1 hypothetical protein 32454 9795844 AARI_pI00240 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915200.1 31702 R 861360 CDS YP_003915201.1 308171871 9795819 complement(32451..34247) 1 NC_014549.1 identified by match to protein family PF02534. The TraG family are bacterial conjugation proteins. These proteins aid the transfer of DNA from the plasmid into the host bacterial chromosome although the exact mechanism of action is unknown; TraG-family bacterial conjugation protein 34247 9795819 AARI_pI00250 Arthrobacter arilaitensis Re117 TraG-family bacterial conjugation protein YP_003915201.1 32451 R 861360 CDS YP_003915202.1 308171872 9795815 complement(34244..35872) 1 NC_014549.1 hypothetical protein 35872 9795815 AARI_pI00260 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915202.1 34244 R 861360 CDS YP_003915203.1 308171873 9795837 complement(35869..37380) 1 NC_014549.1 2 transmembrane helices predicted by TMHMM2.0; hypothetical protein 37380 9795837 AARI_pI00270 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915203.1 35869 R 861360 CDS YP_003915204.1 308171874 9795862 complement(37367..39088) 1 NC_014549.1 6 transmembrane helices predicted by TMHMM2.0; hypothetical protein 39088 9795862 AARI_pI00280 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915204.1 37367 R 861360 CDS YP_003915205.1 308171875 9795854 complement(39095..39841) 1 NC_014549.1 1 transmembrane helice predicted by TMHMM2.0; hypothetical protein 39841 9795854 AARI_pI00290 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915205.1 39095 R 861360 CDS YP_003915206.1 308171876 9795860 complement(39856..40161) 1 NC_014549.1 2 transmembrane helices predicted by TMHMM2.0; hypothetical protein 40161 9795860 AARI_pI00300 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915206.1 39856 R 861360 CDS YP_003915207.1 308171877 9795858 complement(40158..40301) 1 NC_014549.1 hypothetical protein 40301 9795858 AARI_pI00310 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915207.1 40158 R 861360 CDS YP_003915208.1 308171878 9795835 40412..40870 1 NC_014549.1 hypothetical protein 40870 9795835 AARI_pI00320 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915208.1 40412 D 861360 CDS YP_003915209.1 308171879 9795845 40937..41206 1 NC_014549.1 match to protein family TIGR01764; putative excisionase 41206 9795845 AARI_pI00330 Arthrobacter arilaitensis Re117 putative excisionase YP_003915209.1 40937 D 861360 CDS YP_003915210.1 308171880 9795833 41208..41750 1 NC_014549.1 similar to protein SP:Q9X549 (Corynebacterium glutamicum plasmid R-plasmid pAG1). Match to PS51257: prokaryotic membrane lipoprotein lipid attachment site profile; hypothetical protein 41750 9795833 AARI_pI00340 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915210.1 41208 D 861360 CDS YP_003915211.1 308171881 9795824 41753..42820 1 NC_014549.1 identified by match to protein family PF01551. Members of this family are zinc metallopeptidases with a range of specificities. Peptidase family M23 are also endopeptidases. Signal peptide predicted by SignalP 3.0 HMM (probability: 1.000) with cleavage site probability 0. 661 between position 37 and 38; putative secreted M23 family peptidase 42820 9795824 AARI_pI00350 Arthrobacter arilaitensis Re117 putative secreted M23 family peptidase YP_003915211.1 41753 D 861360 CDS YP_003915212.1 308171882 9795843 42835..44235 1 NC_014549.1 hypothetical protein 44235 9795843 AARI_pI00360 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915212.1 42835 D 861360 CDS YP_003915213.1 308171883 9795852 44733..44966 1 NC_014549.1 match to SSF47598: Ribbon-helix-helix superfamily; ribbon-helix-helix domain-containing protein 44966 9795852 AARI_pI00380 Arthrobacter arilaitensis Re117 ribbon-helix-helix domain-containing protein YP_003915213.1 44733 D 861360 CDS YP_003915214.1 308171884 9795823 45210..47144 1 NC_014549.1 hypothetical protein 47144 9795823 AARI_pI00390 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915214.1 45210 D 861360 CDS YP_003915215.1 308171885 9795849 47652..48539 1 NC_014549.1 hypothetical protein 48539 9795849 AARI_pI00400 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915215.1 47652 D 861360 CDS YP_003915216.1 308171886 9795831 48636..48773 1 NC_014549.1 hypothetical protein 48773 9795831 AARI_pI00410 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915216.1 48636 D 861360 CDS YP_003915217.1 308171887 9795826 48855..49262 1 NC_014549.1 hypothetical protein 49262 9795826 AARI_pI00420 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915217.1 48855 D 861360 CDS YP_003915218.1 308171888 9795842 49324..49536 1 NC_014549.1 hypothetical protein 49536 9795842 AARI_pI00430 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915218.1 49324 D 861360 CDS YP_003915219.1 308171889 9795841 49624..49881 1 NC_014549.1 identified by match to protein family PF00462; glutaredoxin-like protein 49881 9795841 AARI_pI00440 Arthrobacter arilaitensis Re117 glutaredoxin-like protein YP_003915219.1 49624 D 861360 CDS YP_003915220.1 308171890 9795847 49935..50195 1 NC_014549.1 hypothetical protein 50195 9795847 AARI_pI00450 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915220.1 49935 D 861360 CDS YP_003915221.1 308175815 9795865 353..1789 1 NC_014550.1 plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; chromosomal replication initiator protein DnaA 1789 dnaA 9795865 dnaA Arthrobacter arilaitensis Re117 chromosomal replication initiator protein DnaA YP_003915221.1 353 D 861360 CDS YP_003915222.1 308175816 9793820 2256..3383 1 NC_014550.1 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The beta chain is required for initiation of replication once it is clamped onto DNA. DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII complex. PolIII associates with the gamma complex (composed of gamma, delta, delta, psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex; DNA polymerase III subunit beta 3383 dnaN 9793820 dnaN Arthrobacter arilaitensis Re117 DNA polymerase III subunit beta YP_003915222.1 2256 D 861360 CDS YP_003915223.1 308175817 9793827 3442..4605 1 NC_014550.1 RecF is a recombinational DNA repair ATPase that maintains replication in the presence of DNA damage. When replication is prematurely disrupted by DNA damage, several recF pathway gene products play critical roles processing the arrested replication fork, allowing it to resume and complete its task.; DNA replication and repair protein RecF 4605 recF 9793827 recF Arthrobacter arilaitensis Re117 DNA replication and repair protein RecF YP_003915223.1 3442 D 861360 CDS YP_003915224.1 308175818 9794287 4598..5155 1 NC_014550.1 match to protein family PF05258. This family contains several actinomycete proteins of unknown function; hypothetical protein 5155 9794287 AARI_00040 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915224.1 4598 D 861360 CDS YP_003915225.1 308175819 9795866 5438..7501 1 NC_014550.1 DNA gyrase negatively supercoils closed circular double-stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings. Made up of two chains. The A chain is responsible for DNA breakage and rejoining; the B chain catalyzes ATP hydrolysis; DNA gyrase subunit B 7501 gyrB 9795866 gyrB Arthrobacter arilaitensis Re117 DNA gyrase subunit B YP_003915225.1 5438 D 861360 CDS YP_003915226.1 308175820 9793944 7560..10187 1 NC_014550.1 DNA gyrase negatively supercoils closed circular double-stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings. Made up of two chains. The A chain is responsible for DNA breakage and rejoining; the B chain catalyzes ATP hydrolysis; DNA gyrase subunit A 10187 gyrA 9793944 gyrA Arthrobacter arilaitensis Re117 DNA gyrase subunit A YP_003915226.1 7560 D 861360 CDS YP_003915227.1 308175821 9793943 10184..10807 1 NC_014550.1 2 transmembrane helices predicted by TMHMM2.0; hypothetical protein 10807 9793943 AARI_00070 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915227.1 10184 D 861360 CDS YP_003915228.1 308175822 9793565 complement(11465..12640) 1 NC_014550.1 match to PF00534: Glycosyl transferases group 1. Proteins containing this domain transfer UDP, ADP, GDP or CMP linked sugars to a variety of substrates, including glycogen, fructose-6-phosphate and lipopolysaccharides. The bacterial enzymes are involved in various biosynthetic processes that include exopolysaccharide biosynthesis, lipopolysaccharide core biosynthesis and the biosynthesis of the slime polysaccaride colanic acid; glycosyl transferase family 1 12640 9793565 AARI_00080 Arthrobacter arilaitensis Re117 glycosyl transferase family 1 YP_003915228.1 11465 R 861360 CDS YP_003915229.1 308175823 9795868 12719..13690 1 NC_014550.1 identified by match to protein family PF01758. Bile acid:Na+ symporter (BASS) family (TC 2.A.28.y.z): these symporters exhibit broad specificity, taking up a variety of non bile organic compounds as well as taurocholate and other bile salts; sodium-dependent transporter 13690 9795868 AARI_00090 Arthrobacter arilaitensis Re117 sodium-dependent transporter YP_003915229.1 12719 D 861360 CDS YP_003915230.1 308175824 9795869 13822..14691 1 NC_014550.1 signal peptide predicted by SignalP 3.0 HMM (probability: 0.973) with cleavage site probability 0.306 between position 22 and 23. 8 transmembrane helices predicted by TMHMM2.0 after the signal peptide; hypothetical protein 14691 9795869 AARI_00100 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915230.1 13822 D 861360 CDS YP_003915231.1 308175825 9795870 complement(14698..14904) 1 NC_014550.1 hypothetical protein 14904 9795870 AARI_00110 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915231.1 14698 R 861360 CDS YP_003915232.1 308175826 9795871 15075..15620 1 NC_014550.1 identified by match to protein family PF00160: Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD. Peptidylprolyl isomerase is an enzyme that accelerates protein folding by catalyzing the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; peptidylprolyl isomerase 15620 ppiA 9795871 ppiA Arthrobacter arilaitensis Re117 peptidylprolyl isomerase YP_003915232.1 15075 D 861360 CDS YP_003915233.1 308175827 9794217 15722..16579 1 NC_014550.1 identified by match to protein family PF01694. This group of proteins contain serine peptidases belonging to the MEROPS peptidase family S54 (Rhomboid, clan S-). They are integral membrane proteins related to the Drosophila melanogaster (Fruit fly) rhomboid protein. 7 transmembrane helices predicted by TMHMM2.0; rhomboid family protein 16579 9794217 AARI_00130 Arthrobacter arilaitensis Re117 rhomboid family protein YP_003915233.1 15722 D 861360 CDS YP_003915234.1 308175828 9795872 complement(17061..17678) 1 NC_014550.1 L-lysine exporter (LysE) family, L-lysine exporter (TC 2.A.75.1.1). Identified by match to protein family PF01810. In Corynebacterium glutamicum, LysE appears to catalyze unidirectional efflux of L-lysine (and other basic amino acids such as L-arginine). The physiological function of the exporter is to excrete excess l-Lysine as a result of natural flux imbalances; L-lysine exporter 17678 lysE 9795872 lysE Arthrobacter arilaitensis Re117 L-lysine exporter YP_003915234.1 17061 R 861360 CDS YP_003915235.1 308175829 9794050 17749..18633 1 NC_014550.1 probable transcriptional regulator of lysE. Identified by similarity to protein SP: P94632 (Corynebacterium glutamicum); lysine export transcriptional regulatory protein LysG 18633 lysG 9794050 lysG Arthrobacter arilaitensis Re117 lysine export transcriptional regulatory protein LysG YP_003915235.1 17749 D 861360 CDS YP_003915236.1 308175830 9794051 18716..19033 1 NC_014550.1 drug/metabolite transporter (DMT) superfamily, small multidrug resistance (SMR) family, quaternary ammonium compound (cetylpyridinium, cetyldimethyl ethylammonium, hexadecyltrimethyl ammonium) efflux pump (TC 2.A.7.1.4). Confers resistance to cetylpyridinium, cetyldimethylethyl ammonium and cetrimide cations; quaternary ammonium compound-resistance protein SugE 19033 sugE 9794051 sugE Arthrobacter arilaitensis Re117 quaternary ammonium compound-resistance protein SugE YP_003915236.1 18716 D 861360 CDS YP_003915237.1 308175831 9794418 complement(19094..19351) 1 NC_014550.1 2 transmembrane helices predicted by TMHMM2.0; hypothetical protein 19351 9794418 AARI_00170 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915237.1 19094 R 861360 CDS YP_003915238.1 308175832 9795873 19574..20350 1 NC_014550.1 identified by match to protein family PF04203. Sortase is a transpeptidase that attaches surface proteins by the threonine of an LPXTG motif to the cell wall; sortase 20350 9795873 AARI_00180 Arthrobacter arilaitensis Re117 sortase YP_003915238.1 19574 D 861360 CDS YP_003915239.1 308175833 9795874 20359..20529 1 NC_014550.1 hypothetical protein 20529 9795874 AARI_00190 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915239.1 20359 D 861360 CDS YP_003915240.1 308175834 9795875 20526..21170 1 NC_014550.1 anthranilate synthase is the first enzyme in the branch pathway in tryptophane biosynthesis. It catalyzes the biosynthesis of anthranilate from chorismate and glutamine; anthranilate synthase component II 21170 trpG 9795875 trpG Arthrobacter arilaitensis Re117 anthranilate synthase component II YP_003915240.1 20526 D 861360 CDS YP_003915241.1 308175835 9794472 complement(21263..21787) 1 NC_014550.1 identified by match to PF00583: acetyltransferase (GNAT) family; GNAT family acetyltransferase 21787 9794472 AARI_00210 Arthrobacter arilaitensis Re117 GNAT family acetyltransferase YP_003915241.1 21263 R 861360 CDS YP_003915242.1 308175836 9795876 22056..22346 1 NC_014550.1 hypothetical protein 22346 9795876 AARI_00220 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915242.1 22056 D 861360 CDS YP_003915243.1 308175837 9795877 complement(22423..22902) 1 NC_014550.1 identified by match to PF00293. Members of the Nudix hydrolase superfamily catalyze the hydrolysis of nucleoside diphosphates linked to other moieties. Substrates of nudix hydrolases include intact and oxidatively damaged nucleoside triphosphates, dinucleoside polyphosphates, nucleotide-sugars and dinucleotide enzymes. These substrates are metabolites or cell signaling molecules that require regulation during different stages of the cell cycle or during periods of stress. In general, the role of the nudix hydrolase is to sanitize the nucleotide pools and to maintain cell viability, thereby serving as surveillance and house- cleaning enzymes; NUDIX hydrolase 22902 9795877 AARI_00230 Arthrobacter arilaitensis Re117 NUDIX hydrolase YP_003915243.1 22423 R 861360 CDS YP_003915244.1 308175838 9795878 23100..23429 1 NC_014550.1 hypothetical protein 23429 9795878 AARI_00240 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915244.1 23100 D 861360 CDS YP_003915245.1 308175839 9795886 complement(27827..28318) 1 NC_014550.1 identified by match to PF00903: glyoxalase/bleomycin resistance protein/dioxygenase superfamily; glyoxalase family protein 28318 9795886 AARI_00320 Arthrobacter arilaitensis Re117 glyoxalase family protein YP_003915245.1 27827 R 861360 CDS YP_003915246.1 308175840 9795887 complement(28611..30524) 1 NC_014550.1 identified by match to protein domain PD000001. Match to PS00108 pattern. Protein kinases are a group of enzymes that possess a catalytic subunit which transfers the gamma phosphate from nucleotide triphosphates (often ATP) to one or more amino acid residues in a protein substrate side chain, resulting in a conformational change affecting protein function. They play a role in a mulititude of cellular processes, including division, proliferation, apoptosis, and differentiation; Ser/Thr protein kinase 30524 9795887 AARI_00330 Arthrobacter arilaitensis Re117 Ser/Thr protein kinase YP_003915246.1 28611 R 861360 CDS YP_003915247.1 308175841 9795888 complement(30521..32326) 1 NC_014550.1 identified by match to protein domain PD000001. Match to PS00108 pattern. Protein kinases are a group of enzymes that possess a catalytic subunit which transfers the gamma phosphate from nucleotide triphosphates (often ATP) to one or more amino acid residues in a protein substrate side chain, resulting in a conformational change affecting protein function. They play a role in a mulititude of cellular processes, including division, proliferation, apoptosis, and differentiation; Ser/Thr protein kinase 32326 9795888 AARI_00340 Arthrobacter arilaitensis Re117 Ser/Thr protein kinase YP_003915247.1 30521 R 861360 CDS YP_003915248.1 308175842 9795889 complement(32323..33786) 1 NC_014550.1 match to PF00905. The large number of penicillin binding proteins, which are represented in this group of sequences, are responsible for the final stages of peptidoglycan biosynthesis for cell wall formation. The proteins synthesise cross-linked peptidoglycan from lipid intermediates, and contain a penicillin-sensitive transpeptidase carboxy-terminal domain; penicillin-binding protein 33786 9795889 AARI_00350 Arthrobacter arilaitensis Re117 penicillin-binding protein YP_003915248.1 32323 R 861360 CDS YP_003915249.1 308175843 9795890 complement(33783..35180) 1 NC_014550.1 plays a role in the stabilization of the FtsZ ring during cell division; cell division protein FtsW 35180 ftsW 9795890 ftsW Arthrobacter arilaitensis Re117 cell division protein FtsW YP_003915249.1 33783 R 861360 CDS YP_003915250.1 308175844 9793867 complement(35177..36571) 1 NC_014550.1 match to PF00481: protein phosphatase 2C; protein phosphatase domain-containing protein 36571 9793867 AARI_00370 Arthrobacter arilaitensis Re117 protein phosphatase domain-containing protein YP_003915250.1 35177 R 861360 CDS YP_003915251.1 308175845 9795891 complement(36575..37054) 1 NC_014550.1 match to PF00498. The forkhead-associated (FHA) domain is a phosphopeptide recognition domain found in many regulatory proteins; FHA domain-containing protein 37054 9795891 AARI_00380 Arthrobacter arilaitensis Re117 FHA domain-containing protein YP_003915251.1 36575 R 861360 CDS YP_003915252.1 308175846 9795892 complement(37051..37866) 1 NC_014550.1 match to PF00498. The forkhead-associated (FHA) domain is a phosphopeptide recognition domain found in many regulatory proteins; FHA domain-containing protein 37866 9795892 AARI_00390 Arthrobacter arilaitensis Re117 FHA domain-containing protein YP_003915252.1 37051 R 861360 CDS YP_003915253.1 308175847 9793566 complement(38316..38771) 1 NC_014550.1 hypothetical protein 38771 9793566 AARI_00400 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915253.1 38316 R 861360 CDS YP_003915254.1 308175848 9795894 38850..39386 1 NC_014550.1 hypothetical protein 39386 9795894 AARI_00410 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915254.1 38850 D 861360 CDS YP_003915255.1 308175849 9795895 complement(39375..39536) 1 NC_014550.1 hypothetical protein 39536 9795895 AARI_00420 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915255.1 39375 R 861360 CDS YP_003915256.1 308175850 9795896 complement(39546..40595) 1 NC_014550.1 match to protein domain PF00356. Numerous bacterial transcription regulatory proteins bind DNA via a helix- turn-helix (HTH) motif. These proteins are very diverse, but for convenience may be grouped into subfamilies on the basis of sequence similarity. One such family groups together a range of proteins, including ascG, ccpA, cytR, ebgR, fruR, galR, galS, lacI, malI, opnR, purF, rafR, rbtR and scrR. Within this family, the HTH motif is situated towards the N-terminus; LacI family transcriptional regulator 40595 9795896 AARI_00430 Arthrobacter arilaitensis Re117 LacI family transcriptional regulator YP_003915256.1 39546 R 861360 CDS YP_003915257.1 308175851 9795897 40746..41717 1 NC_014550.1 catalyzes the hydrolysis of all of the commonly occuring purine and pyrimidine nucleosides into ribose and the associated base, but has a preference for inosine and uridine as substrates; inosine/uridine-preferring nucleoside hydrolase 41717 iunH 9795897 iunH Arthrobacter arilaitensis Re117 inosine/uridine-preferring nucleoside hydrolase YP_003915257.1 40746 D 861360 CDS YP_003915258.1 308175852 9794023 41805..42503 1 NC_014550.1 identified by match to PF01738: dienelactone hydrolase family. Carboxymethylenebutenolidases play a crucial role in chlorocatechol degradation via the modified ortho cleavage pathway; carboxymethylenebutenolidase 42503 9794023 AARI_00450 Arthrobacter arilaitensis Re117 carboxymethylenebutenolidase YP_003915258.1 41805 D 861360 CDS YP_003915259.1 308175853 9795898 42559..42990 1 NC_014550.1 identified by match to PF00582: universal stress protein family. The universal stress protein UspA is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. UspA enhances the rate of cell survival during prolonged exposure to such conditions, and may provide a general stress endurance activity; universal stress family domain-containing protein 42990 9795898 AARI_00460 Arthrobacter arilaitensis Re117 universal stress family domain-containing protein YP_003915259.1 42559 D 861360 CDS YP_003915260.1 308175854 9795899 43078..43794 1 NC_014550.1 lysR family transcriptional regulator 43794 9795899 AARI_00470 Arthrobacter arilaitensis Re117 lysR family transcriptional regulator YP_003915260.1 43078 D 861360 CDS YP_003915261.1 308175855 9795900 43837..44625 1 NC_014550.1 match to protein family PF00378. This family contains a diverse set of enzymes including: Enoyl-CoA hydratase, Napthoate synthase, Carnitate racemase, 3- hydoxybutyryl-CoA dehydratase, Dodecanoyl-CoA delta- isomerase; enoyl-CoA hydratase/isomerase 44625 9795900 AARI_00480 Arthrobacter arilaitensis Re117 enoyl-CoA hydratase/isomerase YP_003915261.1 43837 D 861360 CDS YP_003915262.1 308175856 9795901 44640..45305 1 NC_014550.1 hypothetical protein 45305 9795901 AARI_00490 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915262.1 44640 D 861360 CDS YP_003915263.1 308175857 9795902 45315..46214 1 NC_014550.1 fructokinase catalyzes the conversion of fructose to fructose-6-phosphate, which is an entry point into glycolysis via conversion into glucose-6-phosphate; fructokinase 46214 9795902 AARI_00500 Arthrobacter arilaitensis Re117 fructokinase YP_003915263.1 45315 D 861360 CDS YP_003915264.1 308175858 9795903 46215..47009 1 NC_014550.1 match to protein family PF08282: haloacid dehalogenase-like hydrolase. The Haloacid Dehydrogenase (HAD) superfamily includes phosphatases, phosphonatases, P- type ATPases, beta-phosphoglucomutases, phosphomannomutases, and dehalogenases, which are involved in a variety of cellular processes ranging from amino acid biosynthesis to detoxification; haloacid dehalogenase 47009 9795903 AARI_00510 Arthrobacter arilaitensis Re117 haloacid dehalogenase YP_003915264.1 46215 D 861360 CDS YP_003915265.1 308175859 9795904 47006..47737 1 NC_014550.1 glycerophosphoryl diester phosphodiesterases display broad specificity for glycerophosphodiesters; glycerophosphocholine, glycerophosphoethanolamine, glycerophosphoglycerol, and bis(glycerophosphoglycerol); glycerophosphodiester phosphodiesterase 47737 glpQ 9795904 glpQ Arthrobacter arilaitensis Re117 glycerophosphodiester phosphodiesterase YP_003915265.1 47006 D 861360 CDS YP_003915266.1 308175860 9793912 complement(47734..48711) 1 NC_014550.1 hypothetical protein 48711 9793912 AARI_00530 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915266.1 47734 R 861360 CDS YP_003915267.1 308175861 9795905 48804..51986 1 NC_014550.1 glycosyl hydrolase family 65 protein 51986 9795905 AARI_00540 Arthrobacter arilaitensis Re117 glycosyl hydrolase family 65 protein YP_003915267.1 48804 D 861360 CDS YP_003915268.1 308175862 9795906 complement(52080..53486) 1 NC_014550.1 major facilitator superfamily, sugar porter family (TC 2.A.1.1.z); MFS superfamily sugar transporter 53486 9795906 AARI_00550 Arthrobacter arilaitensis Re117 MFS superfamily sugar transporter YP_003915268.1 52080 R 861360 CDS YP_003915269.1 308175863 9795907 complement(53700..54983) 1 NC_014550.1 nucleobase:cation symporter-2 (NCS2) Family (TC 2.A. 40.y.z). Identified by match to protein family PF00860; uracil/xanthine permease 54983 9795907 AARI_00560 Arthrobacter arilaitensis Re117 uracil/xanthine permease YP_003915269.1 53700 R 861360 CDS YP_003915270.1 308175864 9795908 complement(55011..56435) 1 NC_014550.1 involved in thiamin biosynthesis. Catalyzes the phosphorylation of HMP-P to HMP-PP; phosphomethylpyrimidine kinase 56435 thiD 9795908 thiD Arthrobacter arilaitensis Re117 phosphomethylpyrimidine kinase YP_003915270.1 55011 R 861360 CDS YP_003915271.1 308175865 9794440 complement(56432..57073) 1 NC_014550.1 catalyses the following reaction: 2-methyl-4-amino- 5-hydroxymethylpyrimidine diphosphate + 4-methyl-5-(2- phosphono-oxyethyl)thiazole <=> diphosphate + thiamine phosphate; thiamine-phosphate diphosphorylase 57073 thiE 9794440 thiE Arthrobacter arilaitensis Re117 thiamine-phosphate diphosphorylase YP_003915271.1 56432 R 861360 CDS YP_003915272.1 308175866 9794441 complement(57066..57860) 1 NC_014550.1 catalyses the following reaction : ATP + 4-methyl-5- (2-hydroxyethyl)thiazole <=> ADP + 4-methyl-5-(2- phosphonooxyethyl)thiazole; hydroxyethylthiazole kinase 57860 thiM 9794441 thiM Arthrobacter arilaitensis Re117 hydroxyethylthiazole kinase YP_003915272.1 57066 R 861360 CDS YP_003915273.1 308175867 9794445 complement(57979..58347) 1 NC_014550.1 transcriptional regulator 58347 9794445 AARI_00600 Arthrobacter arilaitensis Re117 transcriptional regulator YP_003915273.1 57979 R 861360 CDS YP_003915274.1 308175868 9795909 complement(58344..59882) 1 NC_014550.1 12 transmembrane helices predicted by TMHMM2.0; hypothetical protein 59882 9795909 AARI_00610 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915274.1 58344 R 861360 CDS YP_003915275.1 308175869 9795910 59963..61396 1 NC_014550.1 identified by match to protein family PF00171; aldehyde dehydrogenase family protein 61396 9795910 AARI_00620 Arthrobacter arilaitensis Re117 aldehyde dehydrogenase family protein YP_003915275.1 59963 D 861360 CDS YP_003915276.1 308175870 9795911 61476..62924 1 NC_014550.1 amino acid-polyamine-organocation (APC) superfamily, amino acid transporter (AAT) family, lysine:H+ symporter (TC 2.A.3.1.2). Identified by similarity to protein SP:P25737 (Escherichia coli); lysine-specific permease 62924 lysP 9795911 lysP Arthrobacter arilaitensis Re117 lysine-specific permease YP_003915276.1 61476 D 861360 CDS YP_003915277.1 308175871 9794052 complement(62921..64519) 1 NC_014550.1 catalyzes the interconversion of alpha-D-glucose 1- phosphate to alpha-D-glucose 6-phosphate; phosphoglucomutase 64519 pgm 9794052 pgm Arthrobacter arilaitensis Re117 phosphoglucomutase YP_003915277.1 62921 R 861360 CDS YP_003915278.1 308175872 9795912 complement(64978..66435) 1 NC_014550.1 proton-dependent oligopeptide transporter (POT) family (TC 2.A.17), di- or tripeptide:H+ symporter (TC 2.A. 17.1.1). Identified by match to protein family PF00854; dipeptide/tripeptide permease 66435 9795912 AARI_00660 Arthrobacter arilaitensis Re117 dipeptide/tripeptide permease YP_003915278.1 64978 R 861360 CDS YP_003915279.1 308175873 9795913 complement(66488..67834) 1 NC_014550.1 amidase 67834 9795913 AARI_00670 Arthrobacter arilaitensis Re117 amidase YP_003915279.1 66488 R 861360 CDS YP_003915280.1 308175874 9795914 67902..68228 1 NC_014550.1 identified by match to protein domain PF00581. Rhodanese has an internal duplication. This HMM represents a single copy of this duplicated domain. The domain is found as a single copy in other proteins, including phosphatases and ubiquitin C-terminal hydrolases; rhodanese domain-containing protein 68228 9795914 AARI_00680 Arthrobacter arilaitensis Re117 rhodanese domain-containing protein YP_003915280.1 67902 D 861360 CDS YP_003915281.1 308175875 9795915 68225..69148 1 NC_014550.1 catalyzes the decarboxylation of prephenate into phenylpyruvate. Involved in phenylalanine biosynthesis; prephenate dehydratase 69148 9795915 AARI_00690 Arthrobacter arilaitensis Re117 prephenate dehydratase YP_003915281.1 68225 D 861360 CDS YP_003915282.1 308175876 9795916 complement(69219..70265) 1 NC_014550.1 signal peptide predicted by SignalP 3.0 HMM (probability: 0.999) with cleavage site probability 0.916 between position 19 and 20; hypothetical protein 70265 9795916 AARI_00700 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915282.1 69219 R 861360 CDS YP_003915283.1 308175877 9795917 70304..71581 1 NC_014550.1 activates serine and transfers it to tRNA(Ser) as the first step in protein biosynthesis; serine--tRNA ligase 71581 serS 9795917 serS Arthrobacter arilaitensis Re117 serine--tRNA ligase YP_003915283.1 70304 D 861360 CDS YP_003915284.1 308175878 9794395 71706..72536 1 NC_014550.1 match to protein family PF08282: haloacid dehalogenase-like hydrolase. The Haloacid Dehydrogenase (HAD) superfamily includes phosphatases, phosphonatases, P- type ATPases, beta-phosphoglucomutases, phosphomannomutases, and dehalogenases, which are involved in a variety of cellular processes ranging from amino acid biosynthesis to detoxification; haloacid dehalogenase 72536 9794395 AARI_00720 Arthrobacter arilaitensis Re117 haloacid dehalogenase YP_003915284.1 71706 D 861360 CDS YP_003915285.1 308175879 9795918 complement(72555..73157) 1 NC_014550.1 hypothetical protein 73157 9795918 AARI_00730 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915285.1 72555 R 861360 CDS YP_003915286.1 308175880 9795921 complement(74302..74961) 1 NC_014550.1 selectively removes pyroglutamate (pGlu) from the N- terminus of proteins and peptides. The enzyme appears to play an important role in the activation and inactivation of many N-terminal pyroglutamyl-terminating peptides; pyroglutamyl-peptidase I 74961 pcp 9795921 pcp Arthrobacter arilaitensis Re117 pyroglutamyl-peptidase I YP_003915286.1 74302 R 861360 CDS YP_003915287.1 308175881 9794188 75044..76252 1 NC_014550.1 1 transmembrane helice predicted by TMHMM2.0; hypothetical protein 76252 9794188 AARI_00770 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915287.1 75044 D 861360 CDS YP_003915288.1 308175882 9795922 76314..76655 1 NC_014550.1 hypothetical protein 76655 9795922 AARI_00780 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915288.1 76314 D 861360 CDS YP_003915289.1 308175883 9795923 complement(76714..77193) 1 NC_014550.1 responsible for the hydrolysis of pyrophosphate (PPi) which is formed principally as the product of the many biosynthetic reactions that utilize ATP; inorganic diphosphatase 77193 ppa 9795923 ppa Arthrobacter arilaitensis Re117 inorganic diphosphatase YP_003915289.1 76714 R 861360 CDS YP_003915290.1 308175884 9794215 77291..78655 1 NC_014550.1 identified by match to protein family PF02113. Is involved in the metabolism of cell components; it is synthesised with a leader peptide to target it to the cell membrane. Preferential cleavage: (Ac)(2)-L-Lys-D-Ala-|-D- Ala. Also transpeptidation of peptidyl-alanyl moieties that are N-acyl substituents of D-alanine; serine-type D-Ala-D-Ala carboxypeptidase 78655 9794215 AARI_00800 Arthrobacter arilaitensis Re117 serine-type D-Ala-D-Ala carboxypeptidase YP_003915290.1 77291 D 861360 CDS YP_003915291.1 308175885 9795924 78674..79600 1 NC_014550.1 hypothetical protein 79600 9795924 AARI_00810 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915291.1 78674 D 861360 CDS YP_003915292.1 308175886 9795925 79597..80523 1 NC_014550.1 ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine; tRNA(Ile)-lysidine synthase 80523 tilS 9795925 tilS Arthrobacter arilaitensis Re117 tRNA(Ile)-lysidine synthase YP_003915292.1 79597 D 861360 CDS YP_003915293.1 308175887 9794454 80588..81139 1 NC_014550.1 catalyses the formation of IMP and diphosphate from hypoxanthine and 5-phospho-alpha-D-ribose 1-diphosphate. Guanine and 6-mercaptopurine can replace hypoxanthine. This enzyme is essential for salvaging exogenous purine bases; hypoxanthine phosphoribosyltransferase 81139 hpt 9794454 hpt Arthrobacter arilaitensis Re117 hypoxanthine phosphoribosyltransferase YP_003915293.1 80588 D 861360 CDS YP_003915294.1 308175888 9793975 81247..83172 1 NC_014550.1 FtsH is a membrane-anchored ATP-dependent protease that degrades misfolded or misassembled membrane proteins as well as a subset of cytoplasmic regulatory proteins. 2 transmembrane helices predicted by TMHMM2.0; cell division protein FtsH 83172 ftsH 9793975 ftsH Arthrobacter arilaitensis Re117 cell division protein FtsH YP_003915294.1 81247 D 861360 CDS YP_003915295.1 308175889 9793865 83182..83760 1 NC_014550.1 catalyzes the biosynthesis of formic acid and dihydroneopterin triphosphate from GTP : GTP + H2O <=> formate + 2-amino-4-hydroxy-6-(erythro-1,2,3- trihydroxypropyl)- dihydropteridine triphosphate; GTP cyclohydrolase I 83760 folE 9793865 folE Arthrobacter arilaitensis Re117 GTP cyclohydrolase I YP_003915295.1 83182 D 861360 CDS YP_003915296.1 308175890 9793860 83769..84671 1 NC_014550.1 catalyzes the condensation of 6-hydroxymethyl-7,8- dihydropteridine pyrophosphate to para-aminobenzoic acid to form 7,8-dihydropteroate. This is the second step in the three steps pathway leading from 6-hydroxymethyl-7,8- dihydropterin to 7,8-dihydrofolate. It is the target of sulfonamides which are substrates analog that compete with para-aminobenzoic acid; dihydropteroate synthase 84671 folP 9793860 folP Arthrobacter arilaitensis Re117 dihydropteroate synthase YP_003915296.1 83769 D 861360 CDS YP_003915297.1 308175891 9793861 84658..85491 1 NC_014550.1 EC 4.1.2.25 catalyzes the following reaction: 2- amino-4-hydroxy-6-(D-erythro-1,2,3-trihydroxypropyl)-7, 8- dihydropteridine <=> 2-amino-4-hydroxy-6-hydroxymethyl-7, 8- dihydropteridine + glycolaldehyde. EC 2.7.6.3 catalyses the following reaction: ATP + 2-amino-4-hydroxy-6- hydroxymethyl-7,8-dihydropteridine <=> AMP + (2-amino-4- hydroxy-7,8-dihydropteridin-6-yl)methyl diphosphate; bifunctional dihydroneopterin aldolase/2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 85491 folBK 9793861 folBK Arthrobacter arilaitensis Re117 bifunctional dihydroneopterin aldolase/2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase YP_003915297.1 84658 D 861360 CDS YP_003915298.1 308175892 9793857 85488..85949 1 NC_014550.1 signal peptide predicted by SignalP 3.0 HMM (probability: 0.991) with cleavage site probability 0.734 between position 31 and 32. 3 transmembrane helices predicted by TMHMM2.0 after the signal peptide; hypothetical protein 85949 9793857 AARI_00880 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915298.1 85488 D 861360 CDS YP_003915299.1 308175893 9795926 85975..86415 1 NC_014550.1 2 transmembrane helices predicted by TMHMM2.0; hypothetical protein 86415 9795926 AARI_00890 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915299.1 85975 D 861360 CDS YP_003915300.1 308175894 9795927 86412..87809 1 NC_014550.1 4 transmembrane helices predicted by TMHMM2.0; hypothetical protein 87809 9795927 AARI_00900 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915300.1 86412 D 861360 CDS YP_003915301.1 308175895 9795928 87812..88678 1 NC_014550.1 hypothetical protein 88678 9795928 AARI_00910 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915301.1 87812 D 861360 CDS YP_003915302.1 308175896 9795929 88683..89549 1 NC_014550.1 catalyzes the formation of pantothenate from pantoate and beta-alanine; pantoate--beta-alanine ligase 89549 panC 9795929 panC Arthrobacter arilaitensis Re117 pantoate--beta-alanine ligase YP_003915302.1 88683 D 861360 CDS YP_003915303.1 308175897 9794174 complement(89546..90499) 1 NC_014550.1 identified by match to protein family PF03060: 2- nitropropane dioxygenase; 2-nitropropane dioxygenase-like protein 90499 9794174 AARI_00930 Arthrobacter arilaitensis Re117 2-nitropropane dioxygenase-like protein YP_003915303.1 89546 R 861360 CDS YP_003915304.1 308175898 9793569 96904..96996 1 NC_014550.1 hypothetical protein 96996 9793569 AARI_00940 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915304.1 96904 D 861360 CDS YP_003915305.1 308175899 9795931 97559..97759 1 NC_014550.1 match to PF01381: helix-turn-helix. This is large family of DNA binding helix-turn helix proteins that include a bacterial plasmid copy control protein, bacterial methylases, various bacteriophage transcription control proteins and a vegetative specific protein from Dictyostelium discoideum (Slime mould); hypothetical protein 97759 9795931 AARI_00950 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915305.1 97559 D 861360 CDS YP_003915306.1 308175900 9795932 97756..98952 1 NC_014550.1 identified by match to PF07804 (HipA-like C- terminal domain) and PF07805 (HipA-like N-terminal domain). The HipA protein is known to be involved in high- frequency persistence to the lethal effects of inhibition of either DNA or peptidoglycan synthesis. When expressed alone, it is toxic to bacterial cells but it is usually tightly associated with HipB and the HipA-HipB complex may be involved in autoregulation of the hip operon. The hip proteins may be involved in cell division control and may interact with cell division genes or their products; HipA-like protein 98952 9795932 AARI_00960 Arthrobacter arilaitensis Re117 HipA-like protein YP_003915306.1 97756 D 861360 CDS YP_003915307.1 308175901 9795933 complement(98974..99417) 1 NC_014550.1 hypothetical protein 99417 9795933 AARI_00970 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915307.1 98974 R 861360 CDS YP_003915308.1 308175902 9793572 106102..108075 1 NC_014550.1 identified by match to PF05649 and PF01431; metalloproteinase 108075 9793572 AARI_00980 Arthrobacter arilaitensis Re117 metalloproteinase YP_003915308.1 106102 D 861360 CDS YP_003915309.1 308175903 9795935 108213..109727 1 NC_014550.1 lysine-tRNA ligase 109727 lysS 9795935 lysS Arthrobacter arilaitensis Re117 lysine-tRNA ligase YP_003915309.1 108213 D 861360 CDS YP_003915310.1 308175904 9794054 109729..109896 1 NC_014550.1 hypothetical protein 109896 9794054 AARI_01000 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915310.1 109729 D 861360 CDS YP_003915311.1 308175905 9795936 110035..110355 1 NC_014550.1 hypothetical protein 110355 9795936 AARI_01010 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915311.1 110035 D 861360 CDS YP_003915312.1 308175906 9795937 110617..113139 1 NC_014550.1 ATP-dependent Clp proteases act as chaperones to target the proteases to substrates; ATP-dependent Clp protease ATP-binding subunit 113139 clpC 9795937 clpC Arthrobacter arilaitensis Re117 ATP-dependent Clp protease ATP-binding subunit YP_003915312.1 110617 D 861360 CDS YP_003915313.1 308175907 9793738 113231..113698 1 NC_014550.1 4 transmembrane helices predicted by TMHMM2.0; hypothetical protein 113698 9793738 AARI_01030 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915313.1 113231 D 861360 CDS YP_003915314.1 308175908 9795938 complement(113730..114176) 1 NC_014550.1 hypothetical protein 114176 9795938 AARI_01040 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915314.1 113730 R 861360 CDS YP_003915315.1 308175909 9795939 complement(114189..114596) 1 NC_014550.1 identified by match to PF00903: glyoxalase/bleomycin resistance protein/dioxygenase superfamily; glyoxalase family protein 114596 9795939 AARI_01050 Arthrobacter arilaitensis Re117 glyoxalase family protein YP_003915315.1 114189 R 861360 CDS YP_003915316.1 308175910 9795940 complement(114644..115042) 1 NC_014550.1 identified by match to protein domain PF00165: bacterial regulatory helix-turn-helix proteins, AraC family; AraC family transcriptional regulator 115042 9795940 AARI_01060 Arthrobacter arilaitensis Re117 AraC family transcriptional regulator YP_003915316.1 114644 R 861360 CDS YP_003915317.1 308175911 9795941 complement(115046..116230) 1 NC_014550.1 major facilitator superfamily (TC 2.A.1.y.z). Identified by match to protein family PF07690 (Major Facilitator Superfamily); MFS superfamily transporter 116230 9795941 AARI_01070 Arthrobacter arilaitensis Re117 MFS superfamily transporter YP_003915317.1 115046 R 861360 CDS YP_003915318.1 308175912 9795942 116394..116903 1 NC_014550.1 identified by match to PF00583: acetyltransferase (GNAT) family; GNAT family acetyltransferase 116903 9795942 AARI_01080 Arthrobacter arilaitensis Re117 GNAT family acetyltransferase YP_003915318.1 116394 D 861360 CDS YP_003915319.1 308175913 9795943 complement(116909..117709) 1 NC_014550.1 6 transmembrane helices predicted by TMHMM2.0; hypothetical protein 117709 9795943 AARI_01090 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915319.1 116909 R 861360 CDS YP_003915320.1 308175914 9795944 complement(117774..118682) 1 NC_014550.1 identified by match to protein domain PF00730. This domain is found in a diverse range of structurally related DNA repair proteins that include: endonuclease III, and DNA glycosylase MutY, an A/G-specific adenine glycosylase. Both of these enzymes have a C terminal iron-sulphur cluster loop (FCL); A/G-specific DNA glycosylase 118682 mutY 9795944 mutY Arthrobacter arilaitensis Re117 A/G-specific DNA glycosylase YP_003915320.1 117774 R 861360 CDS YP_003915321.1 308175915 9794125 118805..119422 1 NC_014550.1 1 transmembrane helice predicted by TMHMM2.0; hypothetical protein 119422 9794125 AARI_01110 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915321.1 118805 D 861360 CDS YP_003915322.1 308175916 9795945 complement(119428..120501) 1 NC_014550.1 participates in a DNA-damage check-point that is active prior to asymmetric division when DNA is damaged; DNA integrity scanning protein DisA 120501 disA 9795945 disA Arthrobacter arilaitensis Re117 DNA integrity scanning protein DisA YP_003915322.1 119428 R 861360 CDS YP_003915323.1 308175917 9793815 complement(120536..121930) 1 NC_014550.1 may play a role in the repair of endogenous alkylation damage; DNA repair protein RadA 121930 radA 9793815 radA Arthrobacter arilaitensis Re117 DNA repair protein RadA YP_003915323.1 120536 R 861360 CDS YP_003915324.1 308175918 9794280 complement(121966..123108) 1 NC_014550.1 hypothetical protein 123108 9794280 AARI_01140 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915324.1 121966 R 861360 CDS YP_003915325.1 308175919 9795946 123321..124436 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, phosphate uptake transporter (PhoT) family, phosphate transporter (TC 3.A.1.7.2). ABCISSE: ABC transporter, binding protein (BP), MOI-family, phosphate import. Part of the ABC transporter complex PstSACB involved in phosphate import. The complex is composed of two ATP- binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS); phosphate ABC transporter substrate-binding protein PstS 124436 pstS 9795946 pstS Arthrobacter arilaitensis Re117 phosphate ABC transporter substrate-binding protein PstS YP_003915325.1 123321 D 861360 CDS YP_003915326.1 308175920 9794238 124556..125491 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, phosphate uptake transporter (PhoT) family, phosphate transporter (TC 3.A.1.7.2). ABCISSE: ABC transporter, permease (IM), MOI-family, phosphate import. Part of the ABC transporter complex pstSACB involved in phosphate import. The complex is composed of two ATP-binding proteins (pstB), two transmembrane proteins (pstC and pstA) and a solute-binding protein (pstS); phosphate ABC transporter inner membrane subunit PstC 125491 pstC 9794238 pstC Arthrobacter arilaitensis Re117 phosphate ABC transporter inner membrane subunit PstC YP_003915326.1 124556 D 861360 CDS YP_003915327.1 308175921 9794237 125491..126630 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, phosphate uptake transporter (PhoT) family, phosphate transporter (TC 3.A.1.7.2). ABCISSE: ABC transporter, permease (IM), MOI-family, phosphate import. Part of the ABC transporter complex pstSACB involved in phosphate import. The complex is composed of two ATP-binding proteins (pstB), two transmembrane proteins (pstC and pstA) and a solute-binding protein (pstS); phosphate ABC transporter inner membrane subunit PstA 126630 pstA 9794237 pstA Arthrobacter arilaitensis Re117 phosphate ABC transporter inner membrane subunit PstA YP_003915327.1 125491 D 861360 CDS YP_003915328.1 308175922 9794235 126677..127456 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, phosphate uptake transporter (PhoT) family, phosphate transporter (TC 3.A.1.7.2). ABCISSE: ABC transporter, ATP- binding protein (ABC), MOI-family, phosphate import. Part of the ABC transporter complex pstSACB involved in phosphate import. The complex is composed of two ATP- binding proteins (pstB), two transmembrane proteins (pstC and pstA) and a solute-binding protein (pstS); phosphate ABC transporter ATP-binding subunit PstB 127456 pstB 9794235 pstB Arthrobacter arilaitensis Re117 phosphate ABC transporter ATP-binding subunit PstB YP_003915328.1 126677 D 861360 CDS YP_003915329.1 308175923 9794236 127466..127585 1 NC_014550.1 hypothetical protein 127585 9794236 AARI_01190 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915329.1 127466 D 861360 CDS YP_003915330.1 308175924 9795947 127667..128134 1 NC_014550.1 4 transmembrane helices predicted by TMHMM2.0; hypothetical protein 128134 9795947 AARI_01200 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915330.1 127667 D 861360 CDS YP_003915331.1 308175925 9796029 128134..128625 1 NC_014550.1 4 transmembrane helices predicted by TMHMM2.0; hypothetical protein 128625 9796029 AARI_01210 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915331.1 128134 D 861360 CDS YP_003915332.1 308175926 9796030 128625..128822 1 NC_014550.1 match to protein domain PF01381: helix-turn-helix; transcriptional regulator 128822 9796030 AARI_01220 Arthrobacter arilaitensis Re117 transcriptional regulator YP_003915332.1 128625 D 861360 CDS YP_003915333.1 308175927 9796031 complement(128819..129847) 1 NC_014550.1 inorganic phosphate transporter (PiT) family (TC 2. A.20.y.z). Identified by match to protein family PF01384; phosphate transporter 129847 9796031 AARI_01230 Arthrobacter arilaitensis Re117 phosphate transporter YP_003915333.1 128819 R 861360 CDS YP_003915334.1 308175928 9796032 complement(129852..130481) 1 NC_014550.1 hypothetical protein 130481 9796032 AARI_01240 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915334.1 129852 R 861360 CDS YP_003915335.1 308175929 9796033 130526..130645 1 NC_014550.1 hypothetical protein 130645 9796033 AARI_01250 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915335.1 130526 D 861360 CDS YP_003915336.1 308175930 9796034 130841..131086 1 NC_014550.1 hypothetical protein 131086 9796034 AARI_01260 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915336.1 130841 D 861360 CDS YP_003915337.1 308175931 9796035 131139..132584 1 NC_014550.1 transposase of ISAar22, IS481 family 132584 9796035 AARI_34370 Arthrobacter arilaitensis Re117 transposase of ISAar22, IS481 family YP_003915337.1 131139 D 861360 CDS YP_003915338.1 308175932 9796036 complement(133717..134382) 1 NC_014550.1 hypothetical protein 134382 9796036 AARI_01280 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915338.1 133717 R 861360 CDS YP_003915339.1 308175933 9793573 complement(134707..135297) 1 NC_014550.1 identified by match to PF01738: dienelactone hydrolase family; dienelactone hydrolase domain-containing protein 135297 9793573 AARI_01290 Arthrobacter arilaitensis Re117 dienelactone hydrolase domain-containing protein YP_003915339.1 134707 R 861360 CDS YP_003915340.1 308175934 9796038 complement(135316..135567) 1 NC_014550.1 hypothetical protein 135567 9796038 AARI_01300 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915340.1 135316 R 861360 CDS YP_003915341.1 308175935 9796039 complement(135643..137247) 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, () drug resistance ATPase-1 (Drug RA1) family (TC 3.A.1.120.z). ABCISSE: fused ATP-binding protein (ABC2), ART-family. Duplicated ATPase domains (PF00005); drug resistance ATP-binding protein 137247 9796039 AARI_01310 Arthrobacter arilaitensis Re117 drug resistance ATP-binding protein YP_003915341.1 135643 R 861360 CDS YP_003915342.1 308175936 9796040 complement(137461..138243) 1 NC_014550.1 identified by match to protein family PF02517: CAAX amino terminal protease family. Members of this family are probably proteases (after a prenyl group is attached to the Cys residue in the C-terminal CAAX motif of a protein, the AAX tripeptide is removed by one of the CAAX prenyl proteases). The family contains the Q03530 CAAX prenyl protease. Signal peptide predicted by SignalP 3.0 HMM (probability: 0.755) with cleavage site probability 0.459 between position 27 and 28. 5 transmembrane helices predicted by TMHMM2.0 after the signal peptide; CAAX amino terminal protease 138243 9796040 AARI_01320 Arthrobacter arilaitensis Re117 CAAX amino terminal protease YP_003915342.1 137461 R 861360 CDS YP_003915343.1 308175937 9796041 complement(138406..139107) 1 NC_014550.1 converts dimethylmenaquinone (DMKH2) to menaquinone (MKH2) and converts 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4- benzoquinol (DMQH2); ubiquinone/menaquinone biosynthesis methyltransferase 139107 9796041 AARI_01330 Arthrobacter arilaitensis Re117 ubiquinone/menaquinone biosynthesis methyltransferase YP_003915343.1 138406 R 861360 CDS YP_003915344.1 308175938 9796042 complement(139166..140137) 1 NC_014550.1 activator of Hsp90 ATPase 1-like protein 140137 9796042 AARI_01340 Arthrobacter arilaitensis Re117 activator of Hsp90 ATPase 1-like protein YP_003915344.1 139166 R 861360 CDS YP_003915345.1 308175939 9796043 complement(140149..140487) 1 NC_014550.1 identified by match to PF01022. ArsR-family transcriptional regulators include several proteins that appear to dissociate from DNA in the presence of metal ions; ArsR family transcriptional regulator 140487 9796043 AARI_01350 Arthrobacter arilaitensis Re117 ArsR family transcriptional regulator YP_003915345.1 140149 R 861360 CDS YP_003915346.1 308175940 9796044 140708..141928 1 NC_014550.1 transcriptional regulator 141928 9796044 AARI_01360 Arthrobacter arilaitensis Re117 transcriptional regulator YP_003915346.1 140708 D 861360 CDS YP_003915347.1 308175941 9796045 142094..143617 1 NC_014550.1 catalyses the following reaction: an aldehyde + NAD(+) + H(2)O <=> an acid + NADH; aldehyde dehydrogenase 143617 9796045 AARI_01370 Arthrobacter arilaitensis Re117 aldehyde dehydrogenase YP_003915347.1 142094 D 861360 CDS YP_003915348.1 308175942 9796046 143767..144798 1 NC_014550.1 catalyses the following reaction: an alcohol + NAD(+) <=> an aldehyde or ketone + NADH; Zn-dependent alcohol dehydrogenase 144798 9796046 AARI_01380 Arthrobacter arilaitensis Re117 Zn-dependent alcohol dehydrogenase YP_003915348.1 143767 D 861360 CDS YP_003915349.1 308175943 9796047 144967..145392 1 NC_014550.1 hypothetical protein 145392 9796047 AARI_01390 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915349.1 144967 D 861360 CDS YP_003915350.1 308175944 9796048 145402..145854 1 NC_014550.1 identified by similarity to protein SP:P94957 (Micrococcus luteus). It is a DNA excision repair enzyme. Also named UV endonuclease (cyclobutane pyrimidine dimer- DNA glycosylase/abasic lyase); pyrimidine dimer DNA glycosylase 145854 uveA 9796048 uveA Arthrobacter arilaitensis Re117 pyrimidine dimer DNA glycosylase YP_003915350.1 145402 D 861360 CDS YP_003915351.1 308175945 9794494 complement(145875..146858) 1 NC_014550.1 catalyses the following reaction: L-2-amino-6- oxoheptanedioate + NH(3) + NADPH <=> meso-2,6- diaminoheptanedioate + H(2)O + NADP(+). Involved in lysine biosynthesis; diaminopimelate dehydrogenase 146858 ddh 9794494 ddh Arthrobacter arilaitensis Re117 diaminopimelate dehydrogenase YP_003915351.1 145875 R 861360 CDS YP_003915352.1 308175946 9793797 complement(146972..147130) 1 NC_014550.1 hypothetical protein 147130 9793797 AARI_01420 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915352.1 146972 R 861360 CDS YP_003915353.1 308175947 9796049 complement(147158..147439) 1 NC_014550.1 hypothetical protein 147439 9796049 AARI_01430 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915353.1 147158 R 861360 CDS YP_003915354.1 308175948 9796050 complement(147436..147786) 1 NC_014550.1 serves as a general protein disulphide oxidoreductase. It interacts with a broad range of proteins by a redox mechanism based on reversible oxidation of 2 cysteine thiol groups to a disulphide, accompanied by the transfer of 2 electrons and 2 protons. The net result is the covalent interconversion of a disulphide and a dithiol; thioredoxin 147786 trx 9796050 trx Arthrobacter arilaitensis Re117 thioredoxin YP_003915354.1 147436 R 861360 CDS YP_003915355.1 308175949 9794478 complement(147786..148652) 1 NC_014550.1 8 transmembrane helices predicted by TMHMM2.0; hypothetical protein 148652 9794478 AARI_01450 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915355.1 147786 R 861360 CDS YP_003915356.1 308175950 9796051 complement(148656..149195) 1 NC_014550.1 identified by match to protein domain PF00581. Rhodanese has an internal duplication. This HMM represents a single copy of this duplicated domain. The domain is found as a single copy in other proteins, including phosphatases and ubiquitin C-terminal hydrolases; rhodanese domain-containing protein 149195 9796051 AARI_01460 Arthrobacter arilaitensis Re117 rhodanese domain-containing protein YP_003915356.1 148656 R 861360 CDS YP_003915357.1 308175951 9796052 complement(149227..150612) 1 NC_014550.1 identified by match to PF00753: metallo-beta- lactamase superfamily. Apart from the beta-lactamases, a number of other proteins contain this domain. These proteins include thiolesterases, members of the glyoxalase II family, that catalyse the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid and a competence protein that is essential for natural transformation in Neisseria gonorrhoeae and could be a transporter involved in DNA uptake; metallo-beta-lactamase 150612 9796052 AARI_01470 Arthrobacter arilaitensis Re117 metallo-beta-lactamase YP_003915357.1 149227 R 861360 CDS YP_003915358.1 308175952 9796053 complement(150733..151185) 1 NC_014550.1 hypothetical protein 151185 9796053 AARI_01480 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915358.1 150733 R 861360 CDS YP_003915359.1 308175953 9796054 complement(151223..151822) 1 NC_014550.1 match to PF00440: bacterial regulatory proteins, tetR family; transcriptional regulator 151822 9796054 AARI_01490 Arthrobacter arilaitensis Re117 transcriptional regulator YP_003915359.1 151223 R 861360 CDS YP_003915360.1 308175954 9796055 152015..152365 1 NC_014550.1 identified by match to protein family PF02566: OsmC, OsmC-like protein. Osmotically inducible protein C (OsmC) is a stress-induced protein found in Escherichia coli. This family also contains an organic hydroperoxide detoxification protein that has a novel pattern of oxidative stress regulation; OsmC-like protein 152365 9796055 AARI_01500 Arthrobacter arilaitensis Re117 OsmC-like protein YP_003915360.1 152015 D 861360 CDS YP_003915361.1 308175955 9796058 complement(152924..153577) 1 NC_014550.1 identified by match to protein family PF00392. This family of regulatory proteins consists of the N-terminal HTH region of GntR-like bacterial transcription factors. At the C-terminus there is usually an effector- binding/oligomerisation domain. The GntR-like proteins can be divided into six sub-families: MocR, YtrR, FadR, AraR, HutC and PlmA. Many of these proteins have been shown experimentally to be autoregulatory, enabling the prediction of operator sites and the discovery of cis/trans relationships; GntR family transcriptional regulator 153577 9796058 AARI_01530 Arthrobacter arilaitensis Re117 GntR family transcriptional regulator YP_003915361.1 152924 R 861360 CDS YP_003915362.1 308175956 9796059 153708..156539 1 NC_014550.1 identified by match to PF02913 and PF01565; FAD linked oxidase domain-containing protein 156539 9796059 AARI_01540 Arthrobacter arilaitensis Re117 FAD linked oxidase domain-containing protein YP_003915362.1 153708 D 861360 CDS YP_003915363.1 308175957 9796060 complement(156622..158082) 1 NC_014550.1 identified by match to SM00507; HNH endonuclease domain-containing protein 158082 9796060 AARI_01550 Arthrobacter arilaitensis Re117 HNH endonuclease domain-containing protein YP_003915363.1 156622 R 861360 CDS YP_003915364.1 308175958 9796061 158392..159873 1 NC_014550.1 amino acid-polyamine-organocation (APC) Superfamily (TC 2.A.3.y.z); amino acid transporter 159873 9796061 AARI_01560 Arthrobacter arilaitensis Re117 amino acid transporter YP_003915364.1 158392 D 861360 CDS YP_003915365.1 308175959 9796062 160003..160272 1 NC_014550.1 hypothetical protein 160272 9796062 AARI_01570 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915365.1 160003 D 861360 CDS YP_003915366.1 308175960 9796063 complement(160295..160765) 1 NC_014550.1 hypothetical protein 160765 9796063 AARI_01580 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915366.1 160295 R 861360 CDS YP_003915367.1 308175961 9796065 161722..162171 1 NC_014550.1 gluconokinase catalyzes the phosphoryl transfer from ATP to gluconate. The resulting product, gluconate-6- phoshate, is an important precursor of gluconate metabolism; gluconokinase 162171 gntK 9796065 gntK Arthrobacter arilaitensis Re117 gluconokinase YP_003915367.1 161722 D 861360 CDS YP_003915368.1 308175962 9793931 162264..162428 1 NC_014550.1 hypothetical protein 162428 9793931 AARI_01610 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915368.1 162264 D 861360 CDS YP_003915369.1 308175963 9796066 162697..164367 1 NC_014550.1 identified by match to protein domain PF00205. Thiamine pyrophosphate binding domains are present in enzymes such as acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase and phosphonopyruvate decarboxylase; thiamine pyrophosphate binding domain-containing protein 164367 9796066 AARI_01620 Arthrobacter arilaitensis Re117 thiamine pyrophosphate binding domain-containing protein YP_003915369.1 162697 D 861360 CDS YP_003915370.1 308175964 9796067 164390..165478 1 NC_014550.1 signal peptide predicted by SignalP 3.0 HMM (probability: 1) with cleavage site probability 0.973 between position 26 and 27; hypothetical protein 165478 9796067 AARI_01630 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915370.1 164390 D 861360 CDS YP_003915371.1 308175965 9796068 complement(165475..166776) 1 NC_014550.1 FAD-linked oxidoreductase 166776 9796068 AARI_01640 Arthrobacter arilaitensis Re117 FAD-linked oxidoreductase YP_003915371.1 165475 R 861360 CDS YP_003915372.1 308175966 9796069 complement(166773..167963) 1 NC_014550.1 hypothetical protein 167963 9796069 AARI_01650 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915372.1 166773 R 861360 CDS YP_003915373.1 308175967 9796070 168077..168841 1 NC_014550.1 hypothetical protein 168841 9796070 AARI_01660 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915373.1 168077 D 861360 CDS YP_003915374.1 308175968 9793576 175227..175784 1 NC_014550.1 match to protein domain PF01872. This domain is found in the C-terminus of the bifunctional deaminase- reductase in combination with PF00383 as well as in isolation in some archaebacterial proteins; RibD domain-containing protein 175784 9793576 AARI_01670 Arthrobacter arilaitensis Re117 RibD domain-containing protein YP_003915374.1 175227 D 861360 CDS YP_003915375.1 308175969 9796072 complement(175843..177330) 1 NC_014550.1 mannitol 2-dehydrogenase catalyzes the NAD- dependent reduction of mannitol to fructose; mannitol 2-dehydrogenase 177330 mtlK 9796072 mtlK Arthrobacter arilaitensis Re117 mannitol 2-dehydrogenase YP_003915375.1 175843 R 861360 CDS YP_003915376.1 308175970 9794113 complement(177368..178693) 1 NC_014550.1 major facilitator superfamily, polyol porter (PP) family (TC 2.A.1.18.z). Possible mannitol transporter; polyol transporter 178693 9794113 AARI_01690 Arthrobacter arilaitensis Re117 polyol transporter YP_003915376.1 177368 R 861360 CDS YP_003915377.1 308175971 9796073 178833..179669 1 NC_014550.1 DeoR-like transcription repressors occur in diverse bacteria as regulators of sugar and nucleoside metabolic systems. The effector molecules for deoR-like regulators are generally phosphorylated intermediates of the relevant metabolic pathway; DeoR family transcriptional regulator 179669 9796073 AARI_01700 Arthrobacter arilaitensis Re117 DeoR family transcriptional regulator YP_003915377.1 178833 D 861360 CDS YP_003915378.1 308175972 9796074 179666..181054 1 NC_014550.1 catalyses the following reaction: ATP + D-xylulose <=> ADP + D-xylulose 5-phosphate. Involved in the catabolism of xylose; xylulokinase 181054 xylB 9796074 xylB Arthrobacter arilaitensis Re117 xylulokinase YP_003915378.1 179666 D 861360 CDS YP_003915379.1 308175973 9794513 181081..181950 1 NC_014550.1 glycerophosphoryl diester phosphodiesterases display broad specificity for glycerophosphodiesters; glycerophosphocholine, glycerophosphoethanolamine, glycerophosphoglycerol, and bis(glycerophosphoglycerol); glycerophosphodiester phosphodiesterase 181950 glpQ 9794513 glpQ Arthrobacter arilaitensis Re117 glycerophosphodiester phosphodiesterase YP_003915379.1 181081 D 861360 CDS YP_003915380.1 308175974 9793913 181956..182639 1 NC_014550.1 hypothetical protein 182639 9793913 AARI_01730 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915380.1 181956 D 861360 CDS YP_003915381.1 308175975 9796075 182662..183351 1 NC_014550.1 identified by match to protein family PF03591; AzlC family protein 183351 9796075 AARI_01740 Arthrobacter arilaitensis Re117 AzlC family protein YP_003915381.1 182662 D 861360 CDS YP_003915382.1 308175976 9796076 183348..183665 1 NC_014550.1 3 transmembrane helices predicted by TMHMM2.0; hypothetical protein 183665 9796076 AARI_01750 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915382.1 183348 D 861360 CDS YP_003915383.1 308175977 9796077 183718..184038 1 NC_014550.1 hypothetical protein 184038 9796077 AARI_01760 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915383.1 183718 D 861360 CDS YP_003915384.1 308175978 9796078 184035..184724 1 NC_014550.1 match to PF01596. This family includes catechol o- methyltransferase, caffeoyl-CoA O-methyltransferase and a family of bacterial O-methyltransferases that may be involved in antibiotic production; O-methyltransferase 184724 9796078 AARI_01770 Arthrobacter arilaitensis Re117 O-methyltransferase YP_003915384.1 184035 D 861360 CDS YP_003915385.1 308175979 9796079 complement(184729..185082) 1 NC_014550.1 3 transmembrane helices predicted by TMHMM2.0; hypothetical protein 185082 9796079 AARI_01780 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915385.1 184729 R 861360 CDS YP_003915386.1 308175980 9796080 185251..185766 1 NC_014550.1 identified by match to PF00583: acetyltransferase (GNAT) family; GNAT family acetyltransferase 185766 9796080 AARI_01790 Arthrobacter arilaitensis Re117 GNAT family acetyltransferase YP_003915386.1 185251 D 861360 CDS YP_003915387.1 308175981 9796081 185783..186586 1 NC_014550.1 hypothetical protein 186586 9796081 AARI_01800 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915387.1 185783 D 861360 CDS YP_003915388.1 308175982 9796082 complement(186583..187092) 1 NC_014550.1 hypothetical protein 187092 9796082 AARI_01810 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915388.1 186583 R 861360 CDS YP_003915389.1 308175983 9796083 complement(187183..188634) 1 NC_014550.1 major facilitator superfamily, AzgA family purine transporter (TC 2.A.1.40.z); purine transporter 188634 9796083 AARI_01820 Arthrobacter arilaitensis Re117 purine transporter YP_003915389.1 187183 R 861360 CDS YP_003915390.1 308175984 9796084 188804..189781 1 NC_014550.1 identified by match to PF00582: universal stress protein family. The universal stress protein UspA is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. UspA enhances the rate of cell survival during prolonged exposure to such conditions, and may provide a general stress endurance activity; universal stress family domain-containing protein 189781 9796084 AARI_01830 Arthrobacter arilaitensis Re117 universal stress family domain-containing protein YP_003915390.1 188804 D 861360 CDS YP_003915391.1 308175985 9796085 complement(189859..191556) 1 NC_014550.1 Signal peptide predicted by SignalP 3.0 HMM (probability: 1.000) with cleavage site probability 0.432 between position 29 and 30; hypothetical protein 191556 9796085 AARI_01840 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915391.1 189859 R 861360 CDS YP_003915392.1 308175986 9796086 complement(192227..192598) 1 NC_014550.1 match to PS00142 pattern: neutral zinc metallopeptidases, zinc-binding region signature; hypothetical protein 192598 9796086 AARI_01850 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915392.1 192227 R 861360 CDS YP_003915393.1 308175987 9793580 complement(193247..194101) 1 NC_014550.1 hypothetical protein 194101 9793580 AARI_01860 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915393.1 193247 R 861360 CDS YP_003915394.1 308175988 9796088 complement(194104..194904) 1 NC_014550.1 removes the damaged DNA at cytosines and guanines by cleaving on the 3 -side of the apurinic/apyrimidinic sites; exodeoxyribonuclease III 194904 xthA 9796088 xthA Arthrobacter arilaitensis Re117 exodeoxyribonuclease III YP_003915394.1 194104 R 861360 CDS YP_003915395.1 308175989 9794511 195010..196062 1 NC_014550.1 enoyl-CoA hydratase catalyzes the hydratation of 2- trans-enoyl-CoA into 3-hydroxyacyl-CoA; enoyl-CoA hydratase 196062 9794511 AARI_01880 Arthrobacter arilaitensis Re117 enoyl-CoA hydratase YP_003915395.1 195010 D 861360 CDS YP_003915396.1 308175990 9796089 196059..196955 1 NC_014550.1 catalyzes the NAD-dependent, reversible oxidation of 3-hydroxbutyrate to methylmalonate. Involved in the catabolism of valine; 3-hydroxyisobutyrate dehydrogenase 196955 mmsB 9796089 mmsB Arthrobacter arilaitensis Re117 3-hydroxyisobutyrate dehydrogenase YP_003915396.1 196059 D 861360 CDS YP_003915397.1 308175991 9794083 complement(196950..197453) 1 NC_014550.1 identified by match to protein family PF01047. Regulators with the marR-type HTH domain are present in bacteria and archaea and control a variety of biological functions, including resistance to multiple antibiotics, household disinfectants, organic solvents, oxidative stress agents and regulation of the virulence factor synthesis in pathogens of humans and plants. Many of the marR-like regulators respond to aromatic compounds; MarR family transcriptional regulator 197453 9794083 AARI_01900 Arthrobacter arilaitensis Re117 MarR family transcriptional regulator YP_003915397.1 196950 R 861360 CDS YP_003915398.1 308175992 9796090 197710..197913 1 NC_014550.1 hypothetical protein 197913 9796090 AARI_01910 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915398.1 197710 D 861360 CDS YP_003915399.1 308175993 9796091 197910..198350 1 NC_014550.1 4 transmembrane helices predicted by TMHMM2.0; hypothetical protein 198350 9796091 AARI_01920 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915399.1 197910 D 861360 CDS YP_003915400.1 308175994 9796092 198347..198646 1 NC_014550.1 identified by match to PF01022: bacterial regulatory protein, ArsR family. ArsR-family transcriptional regulators include several proteins that appear to dissociate from DNA in the presence of metal ions; ArsR family transcriptional regulator 198646 9796092 AARI_01930 Arthrobacter arilaitensis Re117 ArsR family transcriptional regulator YP_003915400.1 198347 D 861360 CDS YP_003915401.1 308175995 9796093 complement(198650..199474) 1 NC_014550.1 catalyses the final step in de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis, an amide transfer from either ammonia or glutamine to nicotinic acid adenine dinucleotide; NAD(+) synthase 199474 nadE 9796093 nadE Arthrobacter arilaitensis Re117 NAD(+) synthase YP_003915401.1 198650 R 861360 CDS YP_003915402.1 308175996 9794130 complement(199568..200005) 1 NC_014550.1 hypothetical protein 200005 9794130 AARI_01950 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915402.1 199568 R 861360 CDS YP_003915403.1 308175997 9796094 200045..200602 1 NC_014550.1 catalyses the formation of orotidine-5-phosphate from orotate and PRPP. Involved in pyrimidine biosynthesis; orotate phosphoribosyltransferase 200602 pyrE 9796094 pyrE Arthrobacter arilaitensis Re117 orotate phosphoribosyltransferase YP_003915403.1 200045 D 861360 CDS YP_003915404.1 308175998 9794270 complement(200672..201742) 1 NC_014550.1 match to protein domain PF00356. Numerous bacterial transcription regulatory proteins bind DNA via a helix- turn-helix (HTH) motif. These proteins are very diverse, but for convenience may be grouped into subfamilies on the basis of sequence similarity. One such family groups together a range of proteins, including ascG, ccpA, cytR, ebgR, fruR, galR, galS, lacI, malI, opnR, purF, rafR, rbtR and scrR. Within this family, the HTH motif is situated towards the N-terminus; LacI family transcriptional regulator 201742 9794270 AARI_01970 Arthrobacter arilaitensis Re117 LacI family transcriptional regulator YP_003915404.1 200672 R 861360 CDS YP_003915405.1 308175999 9796095 201959..203263 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, carbohydrate uptake transporter-1 (CUT1) family, xylobiose porter (TC 3.A.1.1.21). ABCISSE: ABC transporter, binding protein (BP), OSP-family (oligosaccharides or polyols); xylobiose ABC transporter substrate-binding protein BxlE 203263 bxlE 9796095 bxlE Arthrobacter arilaitensis Re117 xylobiose ABC transporter substrate-binding protein BxlE YP_003915405.1 201959 D 861360 CDS YP_003915406.1 308176000 9793722 203272..204312 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, carbohydrate uptake transporter-1 (CUT1) family, xylobiose porter (TC 3.A.1.1.21). ABCISSE: ABC transporter, permease (IM), OSP-family (oligosaccharides or polyols); xylobiose ABC transporter inner membrane subunit BxlF 204312 bxlF 9793722 bxlF Arthrobacter arilaitensis Re117 xylobiose ABC transporter inner membrane subunit BxlF YP_003915406.1 203272 D 861360 CDS YP_003915407.1 308176001 9793723 204309..205196 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, carbohydrate uptake transporter-1 (CUT1) family, xylobiose porter (TC 3.A.1.1.21). ABCISSE: ABC transporter, permease (IM), OSP-family (oligosaccharides or polyols); xylobiose ABC transporter inner membrane subunit BxlG 205196 bxlG 9793723 bxlG Arthrobacter arilaitensis Re117 xylobiose ABC transporter inner membrane subunit BxlG YP_003915407.1 204309 D 861360 CDS YP_003915408.1 308176002 9793724 205244..207574 1 NC_014550.1 hydrolysis of 1,4-beta-D-xylans, to remove successive D-xylose residues from the non-reducing termini. Also hydrolyzes xylobiose. Identified by similarity to protein SP: Q76BU6 (Streptomyces thermoviolaceus), involved in degradation of xylans; xylan 1,4-beta-xylosidase 207574 bxlA 9793724 bxlA Arthrobacter arilaitensis Re117 xylan 1,4-beta-xylosidase YP_003915408.1 205244 D 861360 CDS YP_003915409.1 308176003 9793721 complement(207578..209086) 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily (TC 3. A.1.y.z), DRI-family. Inverted organization, in which the permease component (IM) is C-terminal with respect to the ABC domain (ABC-IM); ABC transporter ATPase and permease components 209086 9793721 AARI_02020 Arthrobacter arilaitensis Re117 ABC transporter ATPase and permease components YP_003915409.1 207578 R 861360 CDS YP_003915410.1 308176004 9796096 complement(209122..209760) 1 NC_014550.1 transcriptional regulator 209760 9796096 AARI_02030 Arthrobacter arilaitensis Re117 transcriptional regulator YP_003915410.1 209122 R 861360 CDS YP_003915411.1 308176005 9796097 complement(209840..210622) 1 NC_014550.1 in E. coli, NagD is shown to be a nucleotide phosphatase. Its exact function has not been established, but it play a role in cell wall construction or disassembly (N-acetyl-glucosamine metabolism) or involved in NDP / NMP hydrolysis; NagD-like protein 210622 nagD 9796097 nagD Arthrobacter arilaitensis Re117 NagD-like protein YP_003915411.1 209840 R 861360 CDS YP_003915412.1 308176006 9794132 210821..211477 1 NC_014550.1 identified by match to protein family PF00588: SpoU rRNA Methylase family. Possible role in rRNA modification; RNA methyltransferase 211477 9794132 AARI_02050 Arthrobacter arilaitensis Re117 RNA methyltransferase YP_003915412.1 210821 D 861360 CDS YP_003915413.1 308176007 9796098 211589..212998 1 NC_014550.1 identified by match to protein family PF01551. Members of this family are zinc metallopeptidases with a range of specificities. Peptidase family M23 are also endopeptidases. 1 transmembrane helice predicted by TMHMM2. 0; peptidase M23 212998 9796098 AARI_02060 Arthrobacter arilaitensis Re117 peptidase M23 YP_003915413.1 211589 D 861360 CDS YP_003915414.1 308176008 9796099 213195..214217 1 NC_014550.1 catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6-bisphosphate; fructose-bisphosphate aldolase 214217 fba 9796099 fba Arthrobacter arilaitensis Re117 fructose-bisphosphate aldolase YP_003915414.1 213195 D 861360 CDS YP_003915415.1 308176009 9793845 214220..214636 1 NC_014550.1 hypothetical protein 214636 9793845 AARI_02080 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915415.1 214220 D 861360 CDS YP_003915416.1 308176010 9796100 214921..215589 1 NC_014550.1 3 transmembrane helices predicted by TMHMM2.0; hypothetical protein 215589 9796100 AARI_02090 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915416.1 214921 D 861360 CDS YP_003915417.1 308176011 9796101 215589..216407 1 NC_014550.1 hypothetical protein 216407 9796101 AARI_02100 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915417.1 215589 D 861360 CDS YP_003915418.1 308176012 9796102 complement(216424..217092) 1 NC_014550.1 response regulators are key elements in two- component signal transduction systems, which enable bacteria to sense, respond, and adapt to a wide range of environments, stressors, and growth conditions; two-component system response regulator 217092 9796102 AARI_02110 Arthrobacter arilaitensis Re117 two-component system response regulator YP_003915418.1 216424 R 861360 CDS YP_003915419.1 308176013 9796103 complement(217089..218483) 1 NC_014550.1 protein-histidine kinases are key elements in two- component signal transduction systems, which enable bacteria to sense, respond, and adapt to a wide range of environments, stressors, and growth conditions; signal transduction histidine kinase 218483 9796103 AARI_02120 Arthrobacter arilaitensis Re117 signal transduction histidine kinase YP_003915419.1 217089 R 861360 CDS YP_003915420.1 308176014 9796104 complement(218530..218994) 1 NC_014550.1 signal peptide predicted by SignalP 3.0 HMM (probability: 0.998) with cleavage site probability 0.527 between position 29 and 30; hypothetical protein 218994 9796104 AARI_02130 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915420.1 218530 R 861360 CDS YP_003915421.1 308176015 9796105 complement(219066..219515) 1 NC_014550.1 identified by match to protein family PF01037; AsnC/Lrp family transcriptional regulator 219515 9796105 AARI_02140 Arthrobacter arilaitensis Re117 AsnC/Lrp family transcriptional regulator YP_003915421.1 219066 R 861360 CDS YP_003915422.1 308176016 9796106 219681..220961 1 NC_014550.1 identified by match to protein family PTHR14084. Kynureninase catalyzes the hydrolytic cleavage of L- kynurenine to anthranilic acid and L-alanine. Kynurinine is a Trp breakdown product and a precursor for NAD. This reaction is a key step in the catabolism of L-tryptophan by Pseudomonas fluorescens and some other bacteria; kynureninase 220961 kynU 9796106 kynU Arthrobacter arilaitensis Re117 kynureninase YP_003915422.1 219681 D 861360 CDS YP_003915423.1 308176017 9794027 221085..222467 1 NC_014550.1 amino acid-polyamine-organocation (APC) superfamily, amino acid transporter (AAT) family (TC 2.A.3.1.z); amino acid transporter 222467 9794027 AARI_02160 Arthrobacter arilaitensis Re117 amino acid transporter YP_003915423.1 221085 D 861360 CDS YP_003915424.1 308176018 9796107 222573..223196 1 NC_014550.1 catalyzes the formation of thymidine 5-phosphate from thymidine; thymidine kinase 223196 tdk 9796107 tdk Arthrobacter arilaitensis Re117 thymidine kinase YP_003915424.1 222573 D 861360 CDS YP_003915425.1 308176019 9794435 complement(223193..223726) 1 NC_014550.1 identified by match to PF00440: bacterial regulatory proteins, tetR family; TetR family transcriptional regulator 223726 9794435 AARI_02180 Arthrobacter arilaitensis Re117 TetR family transcriptional regulator YP_003915425.1 223193 R 861360 CDS YP_003915426.1 308176020 9796108 complement(223760..225028) 1 NC_014550.1 xylitol oxidase catalyzes the following reaction: xylitol + O(2) <=> xylose + H(2)O(2); xylitol oxidase 225028 9796108 AARI_02190 Arthrobacter arilaitensis Re117 xylitol oxidase YP_003915426.1 223760 R 861360 CDS YP_003915427.1 308176021 9796109 complement(225038..226465) 1 NC_014550.1 catalyses the following reaction: ATP + D-xylulose <=> ADP + D-xylulose 5-phosphate. Involved in the catabolism of xylose; xylulokinase 226465 xylB 9796109 xylB Arthrobacter arilaitensis Re117 xylulokinase YP_003915427.1 225038 R 861360 CDS YP_003915428.1 308176022 9794514 complement(226506..227693) 1 NC_014550.1 catalyzes the interconversion of D-xylose to D- xylulose. It can also isomerize D-ribose to D-ribulose and D-glucose to D-fructose; xylose isomerase 227693 xylA 9794514 xylA Arthrobacter arilaitensis Re117 xylose isomerase YP_003915428.1 226506 R 861360 CDS YP_003915429.1 308176023 9794512 227825..229060 1 NC_014550.1 match to PF00480: ROK family; xylose operon repressor 229060 xylR 9794512 xylR Arthrobacter arilaitensis Re117 xylose operon repressor YP_003915429.1 227825 D 861360 CDS YP_003915430.1 308176024 9794515 complement(229057..229854) 1 NC_014550.1 identified by match to PF00376. Members of the family include the mercuric resistance operon regulatory protein merR; Bacillus subtilis bltR and bmrR; Bacillus glnR; Streptomyces coelicolor hspR; Bradyrhizobium japonicum nolA; Escherichia coli superoxide response regulator soxR; and Streptomyces lividans transcriptional activator tipA; MerR family transcriptional regulator 229854 9794515 AARI_02230 Arthrobacter arilaitensis Re117 MerR family transcriptional regulator YP_003915430.1 229057 R 861360 CDS YP_003915431.1 308176025 9796191 230117..231406 1 NC_014550.1 catalyzes the first step in the conversion of IMP to AMP in de novo purine nucleotide metabolism; adenylosuccinate synthetase 231406 purA 9796191 purA Arthrobacter arilaitensis Re117 adenylosuccinate synthetase YP_003915431.1 230117 D 861360 CDS YP_003915432.1 308176026 9796192 232196..233851 1 NC_014550.1 PRK08199: acetolactate synthase 2 catalytic subunit; acetolactate synthase large subunit 233851 9796192 AARI_02260 Arthrobacter arilaitensis Re117 acetolactate synthase large subunit YP_003915432.1 232196 D 861360 CDS YP_003915433.1 308176027 9796193 complement(234175..235116) 1 NC_014550.1 transposase of ISAar44, IS3 family, IS3 group, orfB 235116 9796193 AARI_34380 Arthrobacter arilaitensis Re117 transposase of ISAar44, IS3 family, IS3 group, orfB YP_003915433.1 234175 R 861360 CDS YP_003915434.1 308176028 9797140 complement(235215..235652) 1 NC_014550.1 transposase of ISAar44, IS3 family, IS3 group, orfA 235652 9797140 AARI_34390 Arthrobacter arilaitensis Re117 transposase of ISAar44, IS3 family, IS3 group, orfA YP_003915434.1 235215 R 861360 CDS YP_003915435.1 308176029 9796194 236585..236878 1 NC_014550.1 transposase of ISAar37, IS3 family, IS3 group, orfA 236878 9796194 AARI_34400 Arthrobacter arilaitensis Re117 transposase of ISAar37, IS3 family, IS3 group, orfA YP_003915435.1 236585 D 861360 CDS YP_003915436.1 308176030 9797142 236773..237795 1 NC_014550.1 transposase of ISAar37, IS3 family, IS3 group, orfB 237795 9797142 AARI_34410 Arthrobacter arilaitensis Re117 transposase of ISAar37, IS3 family, IS3 group, orfB YP_003915436.1 236773 D 861360 CDS YP_003915437.1 308176031 9796195 238986..239363 1 NC_014550.1 hypothetical protein 239363 9796195 AARI_02290 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915437.1 238986 D 861360 CDS YP_003915438.1 308176032 9796196 239478..239909 1 NC_014550.1 hypothetical protein 239909 9796196 AARI_02300 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915438.1 239478 D 861360 CDS YP_003915439.1 308176033 9796198 complement(240509..241813) 1 NC_014550.1 major facilitator superfamily (MFS), drug:H+ antiporter-3 (12 spanner) (DHA3) family, tetracycline resistance determinant TetV (TC 2.A.1.21.3). Identified by similarity to protein SP:O31137 (Mycobacterium smegmatis). Probable drug antiporter which uses the proton motive force for the active efflux of tetracycline; tetracycline-resistance determinant TetV 241813 tetV 9796198 tetV Arthrobacter arilaitensis Re117 tetracycline-resistance determinant TetV YP_003915439.1 240509 R 861360 CDS YP_003915440.1 308176034 9794437 242256..243563 1 NC_014550.1 transposase of ISAar23, ISL3 family 243563 9794437 AARI_34420 Arthrobacter arilaitensis Re117 transposase of ISAar23, ISL3 family YP_003915440.1 242256 D 861360 CDS YP_003915441.1 308176035 9797144 complement(243730..245412) 1 NC_014550.1 phosphotransferase system enzyme I (EI) Family (TC 8.A.7.y.z). Enzyme I of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate transport system in bacteria. The PTS catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; phosphoenolpyruvate--protein phosphotransferase 245412 ptsI 9797144 ptsI Arthrobacter arilaitensis Re117 phosphoenolpyruvate--protein phosphotransferase YP_003915441.1 243730 R 861360 CDS YP_003915442.1 308176036 9796199 complement(247409..248386) 1 NC_014550.1 catalyzes the phosphorylation of fructose-1- phosphate to fructose-1,6-biphosphate. Involved in the catabolism of fructose; 1-phosphofructokinase 248386 fruK 9796199 fruK Arthrobacter arilaitensis Re117 1-phosphofructokinase YP_003915442.1 247409 R 861360 CDS YP_003915443.1 308176037 9793863 complement(248383..249159) 1 NC_014550.1 DeoR-like transcription repressors occur in diverse bacteria as regulators of sugar and nucleoside metabolic systems. The effector molecules for deoR-like regulators are generally phosphorylated intermediates of the relevant metabolic pathway; DeoR family transcriptional regulator 249159 9793863 AARI_02360 Arthrobacter arilaitensis Re117 DeoR family transcriptional regulator YP_003915443.1 248383 R 861360 CDS YP_003915444.1 308176038 9796200 complement(249527..250525) 1 NC_014550.1 identified by match to protein family PF02517: CAAX amino terminal protease family. Members of this family are probably proteases (after a prenyl group is attached to the Cys residue in the C-terminal CAAX motif of a protein, the AAX tripeptide is removed by one of the CAAX prenyl proteases). The family contains the Q03530 CAAX prenyl protease. 8 transmembrane helices predicted by TMHMM2.0; CAAX amino terminal protease 250525 9796200 AARI_02370 Arthrobacter arilaitensis Re117 CAAX amino terminal protease YP_003915444.1 249527 R 861360 CDS YP_003915445.1 308176039 9796201 complement(250547..251188) 1 NC_014550.1 2 transmembrane helices predicted by TMHMM2.0; hypothetical protein 251188 9796201 AARI_02380 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915445.1 250547 R 861360 CDS YP_003915446.1 308176040 9796202 251279..251899 1 NC_014550.1 identified by match to PF00440: bacterial regulatory proteins, tetR family; TetR family transcriptional regulator 251899 9796202 AARI_02390 Arthrobacter arilaitensis Re117 TetR family transcriptional regulator YP_003915446.1 251279 D 861360 CDS YP_003915447.1 308176041 9796204 253139..253318 1 NC_014550.1 hypothetical protein 253318 9796204 AARI_02410 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915447.1 253139 D 861360 CDS YP_003915448.1 308176042 9796205 complement(253766..255073) 1 NC_014550.1 transposase of ISAar23, ISL3 family 255073 9796205 AARI_34430 Arthrobacter arilaitensis Re117 transposase of ISAar23, ISL3 family YP_003915448.1 253766 R 861360 CDS YP_003915449.1 308176043 9797145 complement(255193..255729) 1 NC_014550.1 hypothetical protein 255729 9797145 AARI_02420 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915449.1 255193 R 861360 CDS YP_003915450.1 308176044 9796206 256982..257416 1 NC_014550.1 hypothetical protein 257416 9796206 AARI_02430 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915450.1 256982 D 861360 CDS YP_003915451.1 308176045 9796207 complement(257496..257723) 1 NC_014550.1 2 transmembrane helices predicted by TMHMM2.0; hypothetical protein 257723 9796207 AARI_02440 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915451.1 257496 R 861360 CDS YP_003915452.1 308176046 9796208 complement(258309..258803) 1 NC_014550.1 CoA-binding domain-containing protein 258803 9796208 AARI_02450 Arthrobacter arilaitensis Re117 CoA-binding domain-containing protein YP_003915452.1 258309 R 861360 CDS YP_003915453.1 308176047 9796209 complement(258803..260176) 1 NC_014550.1 catalyses several reactions, including the formation of L-homocysteine from O-acetyl-L-homoserine and H2S, and the formation of L-methionine from O-acetyl-L- homoserine and methanethiol; O-acetylhomoserine aminocarboxypropyltransferase 260176 9796209 AARI_02460 Arthrobacter arilaitensis Re117 O-acetylhomoserine aminocarboxypropyltransferase YP_003915453.1 258803 R 861360 CDS YP_003915454.1 308176048 9796210 260498..261058 1 NC_014550.1 identified by match to protein domain PF00300; phosphoglycerate mutase family protein 261058 9796210 AARI_02470 Arthrobacter arilaitensis Re117 phosphoglycerate mutase family protein YP_003915454.1 260498 D 861360 CDS YP_003915455.1 308176049 9796211 261179..261676 1 NC_014550.1 match to protein family TIGR02937. Sigma-70 family; RNA polymerase sigma factor 261676 9796211 AARI_02480 Arthrobacter arilaitensis Re117 RNA polymerase sigma factor YP_003915455.1 261179 D 861360 CDS YP_003915456.1 308176050 9796212 261673..262299 1 NC_014550.1 involved in the repair of alkylated DNA; methylated-DNA--[protein]-cysteine S-methyltransferase 262299 ogt 9796212 ogt Arthrobacter arilaitensis Re117 methylated-DNA--[protein]-cysteine S-methyltransferase YP_003915456.1 261673 D 861360 CDS YP_003915457.1 308176051 9794156 complement(262397..264577) 1 NC_014550.1 haem-containing catalase-peroxidases are bifunctional antioxidant enzymes that exhibit both catalase and broad-spectrum peroxidase activities, depending on the steady-state concentration of hydrogen peroxide; peroxidase/catalase 264577 9794156 AARI_02500 Arthrobacter arilaitensis Re117 peroxidase/catalase YP_003915457.1 262397 R 861360 CDS YP_003915458.1 308176052 9796213 complement(264680..265108) 1 NC_014550.1 acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes. Match to protein family PF01475; ferric uptake regulation protein 265108 fur 9796213 fur Arthrobacter arilaitensis Re117 ferric uptake regulation protein YP_003915458.1 264680 R 861360 CDS YP_003915459.1 308176053 9793873 266135..267661 1 NC_014550.1 betaine/carnitine/choline fransporter (BCCT) family (TC 2.A.15.y.z); betaine/carnitine/choline transporter 267661 9793873 AARI_02520 Arthrobacter arilaitensis Re117 betaine/carnitine/choline transporter YP_003915459.1 266135 D 861360 CDS YP_003915460.1 308176054 9796214 complement(267727..269688) 1 NC_014550.1 catalyzes the formation of acetyl-CoA from acetate and CoA; acetate--CoA ligase 269688 acsA 9796214 acsA Arthrobacter arilaitensis Re117 acetate--CoA ligase YP_003915460.1 267727 R 861360 CDS YP_003915461.1 308176055 9793654 complement(269753..270580) 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, taurine uptake transporter (TauT) family (TC3.A.1.17). ABCISSE: ABC transporter, permease (IM), OTCN-family (osmoprotectants, taurine, cyanate and nitrate), aliphatic sulfonates import. Part of the ABC transporter complex ssuABC involved in aliphatic sulfonates import. Is also involved in taurine transport; aliphatic sulfonates ABC transporter inner membrane subunit SsuC 270580 ssuC 9793654 ssuC Arthrobacter arilaitensis Re117 aliphatic sulfonates ABC transporter inner membrane subunit SsuC YP_003915461.1 269753 R 861360 CDS YP_003915462.1 308176056 9794408 complement(270587..271609) 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, taurine uptake transporter (TauT) family (TC 3.A.1.17.z). ABCISSE: ABC transporter, permease (IM), OTCN-family (osmoprotectants, taurine, cyanate and nitrate), aliphatic sulfonates import. Part of the ABC transporter complex ssuABC involved in aliphatic sulfonates import; aliphatic sulfonates ABC transporter substrate-binding protein SsuA 271609 ssuA 9794408 ssuA Arthrobacter arilaitensis Re117 aliphatic sulfonates ABC transporter substrate-binding protein SsuA YP_003915462.1 270587 R 861360 CDS YP_003915463.1 308176057 9794406 complement(271695..272516) 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, taurine uptake transporter (TauT) family (TC 3.A.1.17.z). ABCISSE: ABC transporter, ATP-binding protein (ABC), OTCN- family (osmoprotectants, taurine, cyanate and nitrate), aliphatic sulfonates import. Part of the ABC transporter complex ssuABC involved in aliphatic sulfonates import; aliphatic sulfonates ABC transporter ATP-binding subunit SsuB 272516 ssuB 9794406 ssuB Arthrobacter arilaitensis Re117 aliphatic sulfonates ABC transporter ATP-binding subunit SsuB YP_003915463.1 271695 R 861360 CDS YP_003915464.1 308176058 9794407 272997..274328 1 NC_014550.1 possibly involved in the metabolism of lipids. Match to PF08028. Acyl-CoA dehydrogenases catalyze the alpha,beta-dehydrogenation of acyl-CoA thioesters to the corresponding trans 2,3-enoyl CoA-products with concommitant reduction of enzyme-bound FAD; acyl-CoA dehydrogenase 274328 9794407 AARI_02570 Arthrobacter arilaitensis Re117 acyl-CoA dehydrogenase YP_003915464.1 272997 D 861360 CDS YP_003915465.1 308176059 9796215 274382..275785 1 NC_014550.1 possibly involved in the metabolism of lipids. Identified by match to PF00296. Bacterial luciferase is a flavin monooxygenase that catalyses the oxidation of long- chain aldehydes and releases energy in the form of visible light, and which uses flavin as a substrate rather than a cofactor. There are structural similarities between bacterial luciferase and nonfluorescent flavoproteins (LuxF, FP390), alkanesulfonate monooxygenase (SsuD), and coenzyme F420-dependent terahydromethanopterin reductase, which make up clearly related families with somewhat different folds; luciferase-like monooxygenase 275785 9796215 AARI_02580 Arthrobacter arilaitensis Re117 luciferase-like monooxygenase YP_003915465.1 274382 D 861360 CDS YP_003915466.1 308176060 9796216 complement(275862..277685) 1 NC_014550.1 catalyzes the transfer of the gamma-glutamyl moiety of glutathione to an acceptor that may be an amino acid, a peptide or water (forming glutamate); gamma-glutamyltransferase 277685 ggt 9796216 ggt Arthrobacter arilaitensis Re117 gamma-glutamyltransferase YP_003915466.1 275862 R 861360 CDS YP_003915467.1 308176061 9793897 complement(277900..278763) 1 NC_014550.1 hypothetical protein 278763 9793897 AARI_02600 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915467.1 277900 R 861360 CDS YP_003915468.1 308176062 9796217 279257..280276 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, methionine uptake transporter (MUT) family (TC 3.A.1.24.z). ABCISSE: ABC transporter, ATP-binding protein (ABC), DLM-family. Part of the ABC transporter complex MetNIQ involved in methionine import. The complex is composed of two ATP-binding proteins (MetN), two transmembrane proteins (MetI) and a solute-binding protein (MetQ); methionine ABC transporter ATP-binding subunit MetN 280276 metN 9796217 metN Arthrobacter arilaitensis Re117 methionine ABC transporter ATP-binding subunit MetN YP_003915468.1 279257 D 861360 CDS YP_003915469.1 308176063 9794075 280273..280968 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, methionine uptake transporter (MUT) family (TC 3.A.1.24.z). ABCISSE: ABC transporter, permease (IM), DLM- family. Part of the ABC transporter complex MetNIQ involved in methionine import. The complex is composed of two ATP-binding proteins (MetN), two transmembrane proteins (MetI) and a solute-binding protein (MetQ); methionine ABC transporter inner membrane subunit MetI 280968 metI 9794075 metI Arthrobacter arilaitensis Re117 methionine ABC transporter inner membrane subunit MetI YP_003915469.1 280273 D 861360 CDS YP_003915470.1 308176064 9794072 280998..281909 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, methionine uptake transporter (MUT) family (TC 3.A.1.24.z). ABCISSE: ABC transporter, lipoprotein (LPP), DLM-family. Part of the ABC transporter complex metNIQ involved in methionine import. The complex is composed of two ATP-binding proteins (MetN), two transmembrane proteins (MetI) and a solute-binding protein (MetQ); methionine ABC transporter substrate-binding protein MetQ 281909 metQ 9794072 metQ Arthrobacter arilaitensis Re117 methionine ABC transporter substrate-binding protein MetQ YP_003915470.1 280998 D 861360 CDS YP_003915471.1 308176065 9794077 282353..284050 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, peptide/opine/nickel uptake transporter (PepT) family (TC 3.A.1.5). ABCISSE: ABC transporter, binding protein (BP), OPN-family (oligopeptides and nickel), oligopeptides import; dipeptide/oligopeptide ABC transporter substrate-binding protein 284050 9794077 AARI_02640 Arthrobacter arilaitensis Re117 dipeptide/oligopeptide ABC transporter substrate-binding protein YP_003915471.1 282353 D 861360 CDS YP_003915472.1 308176066 9796218 284062..285018 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, peptide/opine/nickel uptake transporter (PepT) family (TC 3.A.1.5.z). ABCISSE: ABC transporter, permease (IM), OPN- family (oligopeptides and nickel), oligopeptides import; dipeptide/oligopeptide ABC transporter inner membrane subunit 285018 9796218 AARI_02650 Arthrobacter arilaitensis Re117 dipeptide/oligopeptide ABC transporter inner membrane subunit YP_003915472.1 284062 D 861360 CDS YP_003915473.1 308176067 9796219 285033..285920 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, peptide/opine/nickel uptake transporter (PepT) family (TC 3.A.1.5.z). ABCISSE: ABC transporter, permease (IM), OPN- family (oligopeptides and nickel), oligopeptides import; dipeptide/oligopeptide ABC transporter inner membrane subunit 285920 9796219 AARI_02660 Arthrobacter arilaitensis Re117 dipeptide/oligopeptide ABC transporter inner membrane subunit YP_003915473.1 285033 D 861360 CDS YP_003915474.1 308176068 9796220 285949..287571 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, peptide/opine/nickel uptake transporter (PepT) family (TC 3.A.1.5.z). ABCISSE: ABC transporter, fused ATP-binding protein (ABC2), OPN-family (oligopeptides and nickel), oligopeptides import; dipeptide/oligopeptide ABC transporter ATP-binding subunit 287571 9796220 AARI_02670 Arthrobacter arilaitensis Re117 dipeptide/oligopeptide ABC transporter ATP-binding subunit YP_003915474.1 285949 D 861360 CDS YP_003915475.1 308176069 9796221 287610..288851 1 NC_014550.1 possibly involved in the metabolism of lipids. Match to PF08028. Acyl-CoA dehydrogenases catalyze the alpha,beta-dehydrogenation of acyl-CoA thioesters to the corresponding trans 2,3-enoyl CoA-products with concommitant reduction of enzyme-bound FAD; acyl-CoA dehydrogenase 288851 9796221 AARI_02680 Arthrobacter arilaitensis Re117 acyl-CoA dehydrogenase YP_003915475.1 287610 D 861360 CDS YP_003915476.1 308176070 9796222 288854..290272 1 NC_014550.1 possibly involved in the metabolism of lipids. Identified by match to PF00296. Bacterial luciferase is a flavin monooxygenase that catalyses the oxidation of long- chain aldehydes and releases energy in the form of visible light, and which uses flavin as a substrate rather than a cofactor. There are structural similarities between bacterial luciferase and nonfluorescent flavoproteins (LuxF, FP390), alkanesulfonate monooxygenase (SsuD), and coenzyme F420-dependent terahydromethanopterin reductase, which make up clearly related families with somewhat different folds; luciferase-like monooxygenase 290272 9796222 AARI_02690 Arthrobacter arilaitensis Re117 luciferase-like monooxygenase YP_003915476.1 288854 D 861360 CDS YP_003915477.1 308176071 9796224 291018..294218 1 NC_014550.1 signal peptide predicted by SignalP 3.0 HMM (probability: 0.987) with cleavage site probability 0.986 between position 61 and 62. 1 transmembrane helice predicted by TMHMM2.0 after the signal peptide; hypothetical protein 294218 9796224 AARI_02710 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915477.1 291018 D 861360 CDS YP_003915478.1 308176072 9796225 294172..295839 1 NC_014550.1 identified by similarity to protein SP:O68212 (Actinomyces naeslundii). Fimbriae mediate bacterial adhesion. C-terminal Gram positive anchor (PF00746); fimbrial structural subunit 295839 fimA 9796225 fimA Arthrobacter arilaitensis Re117 fimbrial structural subunit YP_003915478.1 294172 D 861360 CDS YP_003915479.1 308176073 9793850 295970..296908 1 NC_014550.1 identified by match to protein family PF04203. Sortase is a transpeptidase that attaches surface proteins by the threonine of an LPXTG motif to the cell wall. Possible role in synthesis of functional type 2 fimbriae; sortase 296908 9793850 AARI_02730 Arthrobacter arilaitensis Re117 sortase YP_003915479.1 295970 D 861360 CDS YP_003915480.1 308176074 9796226 296956..297372 1 NC_014550.1 hypothetical protein 297372 9796226 AARI_02740 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915480.1 296956 D 861360 CDS YP_003915481.1 308176075 9796227 297377..297700 1 NC_014550.1 hypothetical protein 297700 9796227 AARI_02750 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915481.1 297377 D 861360 CDS YP_003915482.1 308176076 9796228 297933..298043 1 NC_014550.1 hypothetical protein 298043 9796228 AARI_02760 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915482.1 297933 D 861360 CDS YP_003915483.1 308176077 9796229 298139..299575 1 NC_014550.1 transposase of ISAar8, IS1380 family 299575 9796229 AARI_34440 Arthrobacter arilaitensis Re117 transposase of ISAar8, IS1380 family YP_003915483.1 298139 D 861360 CDS YP_003915484.1 308176078 9797146 complement(299740..301776) 1 NC_014550.1 5 -nucleotidases are enzymes that catalyze the hydrolysis of phosphate esterified at carbon 5 of the ribose and deoxyribose portions of nucleotide molecules; 5'-nucleotidase 301776 9797146 AARI_02770 Arthrobacter arilaitensis Re117 5'-nucleotidase YP_003915484.1 299740 R 861360 CDS YP_003915485.1 308176079 9796230 complement(301894..302091) 1 NC_014550.1 2 transmembrane helices predicted by TMHMM2.0; hypothetical protein 302091 9796230 AARI_02780 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915485.1 301894 R 861360 CDS YP_003915486.1 308176080 9796231 complement(302283..302984) 1 NC_014550.1 signal peptide predicted by SignalP 3.0 HMM (probability: 1.000) with cleavage site probability 0.992 between position 38 and 39; hypothetical protein 302984 9796231 AARI_02790 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915486.1 302283 R 861360 CDS YP_003915487.1 308176081 9796232 303239..303493 1 NC_014550.1 hypothetical protein 303493 9796232 AARI_02800 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915487.1 303239 D 861360 CDS YP_003915488.1 308176082 9796233 303870..304676 1 NC_014550.1 3-oxoacyl-ACP reductase catalyses the following reaction: (3R)-3-hydroxyacyl-[acyl- carrier-protein] + NADP(+) <=> 3-oxoacyl-[acyl-carrier- protein] + NADPH. It is involved in fatty acid biosynthesis; 3-oxoacyl-ACP reductase 304676 fabG 9796233 fabG Arthrobacter arilaitensis Re117 3-oxoacyl-ACP reductase YP_003915488.1 303870 D 861360 CDS YP_003915489.1 308176083 9793838 304673..306019 1 NC_014550.1 monooxygenase 306019 9793838 AARI_02820 Arthrobacter arilaitensis Re117 monooxygenase YP_003915489.1 304673 D 861360 CDS YP_003915490.1 308176084 9796234 complement(305960..307309) 1 NC_014550.1 possibly involved in the intracellular release of iron from iron-siderophore complexes; enterochelin esterase-like protein 307309 9796234 AARI_02830 Arthrobacter arilaitensis Re117 enterochelin esterase-like protein YP_003915490.1 305960 R 861360 CDS YP_003915491.1 308176085 9796235 complement(307299..308183) 1 NC_014550.1 identified by match to protein family PF04954. Match to protein domain PF08021. Possibly involved in removal of iron from iron-siderophore complexes; siderophore-interacting protein 308183 9796235 AARI_02840 Arthrobacter arilaitensis Re117 siderophore-interacting protein YP_003915491.1 307299 R 861360 CDS YP_003915492.1 308176086 9796236 complement(308216..309235) 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, iron chelate uptake transporter (FeCT) family (TC 3.A.1.14.z). ABCISSE: ABC transporter, permease (IM), ISVH-family (iron siderophores, vitamin B12 and hemin); iron-siderophore ABC transporter inner membrane subunit 309235 9796236 AARI_02850 Arthrobacter arilaitensis Re117 iron-siderophore ABC transporter inner membrane subunit YP_003915492.1 308216 R 861360 CDS YP_003915493.1 308176087 9796237 complement(309232..310251) 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, iron chelate uptake transporter (FeCT) family (TC 3.A.1.14.z). ABCISSE: ABC transporter, permease (IM), ISVH-family (iron siderophores, vitamin B12 and hemin); iron-siderophore ABC transporter inner membrane subunit 310251 9796237 AARI_02860 Arthrobacter arilaitensis Re117 iron-siderophore ABC transporter inner membrane subunit YP_003915493.1 309232 R 861360 CDS YP_003915494.1 308176088 9796238 complement(310274..311296) 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, iron chelate uptake transporter (FeCT) family (TC 3.A.1.14.z). ABCISSE: ABC transporter, binding protein (BP), ISVH- family (iron siderophores, vitamin B12 and hemin); iron-siderophore ABC transporter substrate-binding protein 311296 9796238 AARI_02870 Arthrobacter arilaitensis Re117 iron-siderophore ABC transporter substrate-binding protein YP_003915494.1 310274 R 861360 CDS YP_003915495.1 308176089 9796239 complement(311493..312878) 1 NC_014550.1 identified by match to protein domain PF00165: bacterial regulatory helix-turn-helix proteins, AraC family; AraC family transcriptional regulator 312878 9796239 AARI_02880 Arthrobacter arilaitensis Re117 AraC family transcriptional regulator YP_003915495.1 311493 R 861360 CDS YP_003915496.1 308176090 9796240 complement(312868..312978) 1 NC_014550.1 hypothetical protein 312978 9796240 AARI_02890 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915496.1 312868 R 861360 CDS YP_003915497.1 308176091 9796241 complement(313047..314282) 1 NC_014550.1 identified by match to protein family PF04954. Match to protein domain PF08021. Possibly involved in removal of iron from iron-siderophore complexes; siderophore-interacting protein 314282 9796241 AARI_02900 Arthrobacter arilaitensis Re117 siderophore-interacting protein YP_003915497.1 313047 R 861360 CDS YP_003915498.1 308176092 9796242 314485..314832 1 NC_014550.1 identified by match to PF08274 and PF03831. This protein family includes an uncharacterised member designated PhnA in Escherichia coli, part of a large operon associated with alkylphosphonate uptake and carbon- phosphorus bond cleavage (alkylphosphonates utilization as phosphorus source); PhnA protein 314832 9796242 AARI_02910 Arthrobacter arilaitensis Re117 PhnA protein YP_003915498.1 314485 D 861360 CDS YP_003915499.1 308176093 9796243 314988..315602 1 NC_014550.1 hypothetical protein 315602 9796243 AARI_02920 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915499.1 314988 D 861360 CDS YP_003915500.1 308176094 9796244 complement(315664..317979) 1 NC_014550.1 phosphoribosylformylglycinamidine synthase catalyzes the fourth step in the de novo biosynthesis of purines. In Bacillus subtilis it is formed from three proteins: PurS, PurQ and smPurL; phosphoribosylformylglycinamidine synthase subunit L 317979 purL 9796244 purL Arthrobacter arilaitensis Re117 phosphoribosylformylglycinamidine synthase subunit L YP_003915500.1 315664 R 861360 CDS YP_003915501.1 308176095 9794252 complement(317976..318728) 1 NC_014550.1 phosphoribosylformylglycinamidine synthase catalyzes the fourth step in the de novo biosynthesis of purines. In Bacillus subtilis it is formed from three proteins: PurS, PurQ and smPurL; phosphoribosylformylglycinamidine synthase subunit PurQ 318728 purQ 9794252 purQ Arthrobacter arilaitensis Re117 phosphoribosylformylglycinamidine synthase subunit PurQ YP_003915501.1 317976 R 861360 CDS YP_003915502.1 308176096 9794255 complement(318728..318979) 1 NC_014550.1 phosphoribosylformylglycinamidine synthase catalyzes the fourth step in the de novo biosynthesis of purines. In Bacillus subtilis it is formed from three proteins: PurS, PurQ and smPurL; phosphoribosylformylglycinamidine synthase subunit PurS 318979 purS 9794255 purS Arthrobacter arilaitensis Re117 phosphoribosylformylglycinamidine synthase subunit PurS YP_003915502.1 318728 R 861360 CDS YP_003915503.1 308176097 9794256 319162..319611 1 NC_014550.1 hypothetical protein 319611 9794256 AARI_02960 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915503.1 319162 D 861360 CDS YP_003915504.1 308176098 9796245 complement(319616..320608) 1 NC_014550.1 contains ankyrin repeats (PF0023). Such repeats occur in a large number of functionally diverse proteins mainly from eukaryotes. They have been found in proteins of diverse function such as transcriptional initiators, cell-cycle regulators, cytoskeletal, ion transporters and signal transducers The few known examples from prokaryotes and viruses may be the result of horizontal gene transfers; ankyrin repeat protein 320608 9796245 AARI_02970 Arthrobacter arilaitensis Re117 ankyrin repeat protein YP_003915504.1 319616 R 861360 CDS YP_003915505.1 308176099 9796246 320786..321916 1 NC_014550.1 catalyzes the formation of 5-methyl-uridine at position 747 (M-5-U747) in 23S rRNA; 23S rRNA (uracil-5-)-methyltransferase RumB 321916 rumB 9796246 rumB Arthrobacter arilaitensis Re117 23S rRNA (uracil-5-)-methyltransferase RumB YP_003915505.1 320786 D 861360 CDS YP_003915506.1 308176100 9794370 complement(321913..323490) 1 NC_014550.1 CPA superfamily, monovalent cation:proton antiporter-1 (CPA1) family (TC 2.A.36.y.z). Na+/H+ antiporters are key transporters in maintaining the pH of actively metabolising cells; Na+/H+ antiporter 323490 9794370 AARI_02990 Arthrobacter arilaitensis Re117 Na+/H+ antiporter YP_003915506.1 321913 R 861360 CDS YP_003915507.1 308176101 9796247 complement(323538..323969) 1 NC_014550.1 signal peptide predicted by SignalP 3.0 HMM (probability: 1.000) with cleavage site probability 0.735 between position 34 and 35; hypothetical protein 323969 9796247 AARI_03000 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915507.1 323538 R 861360 CDS YP_003915508.1 308176102 9796248 complement(324003..324902) 1 NC_014550.1 hypothetical protein 324902 9796248 AARI_03010 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915508.1 324003 R 861360 CDS YP_003915509.1 308176103 9796249 324981..325538 1 NC_014550.1 hypothetical protein 325538 9796249 AARI_03020 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915509.1 324981 D 861360 CDS YP_003915510.1 308176104 9796250 325684..327033 1 NC_014550.1 identified by match to protein family PF01370: NAD dependent epimerase/dehydratase family. This family of proteins utilise NAD as a cofactor. The proteins in this family use nucleotide-sugar substrates for a variety of chemical reactions; NAD dependent epimerase/dehydratase family protein 327033 9796250 AARI_03030 Arthrobacter arilaitensis Re117 NAD dependent epimerase/dehydratase family protein YP_003915510.1 325684 D 861360 CDS YP_003915511.1 308176105 9796251 327255..328385 1 NC_014550.1 catalyzes the last step in heme biosynthesis: the chelation of a ferrous ion to proto-porphyrin IX, to form protoheme: Protoheme + 2 H+ <=> protoporphyrin + Fe2+; ferrochelatase 328385 hemH 9796251 hemH Arthrobacter arilaitensis Re117 ferrochelatase YP_003915511.1 327255 D 861360 CDS YP_003915512.1 308176106 9793956 328650..328859 1 NC_014550.1 hypothetical protein 328859 9793956 AARI_03050 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915512.1 328650 D 861360 CDS YP_003915513.1 308176107 9796252 complement(328865..330289) 1 NC_014550.1 identified by similarity to protein SP:Q6M8T2 (Corynebacterium glutamicum). IT superfamily, citrate- Mg2+:H+ (CitM) citrate-Ca2+:H+ (CitH) symporter (CitMHS) family (TC 2.A.11.y.z); citrate transporter 330289 citH 9796252 citH Arthrobacter arilaitensis Re117 citrate transporter YP_003915513.1 328865 R 861360 CDS YP_003915514.1 308176108 9796254 332169..332840 1 NC_014550.1 identified by similarity to protein SP:Q8NU70 (Corynebacterium glutamicum). CitAB controls citrate utilization in Corynebacterium glutamicum; two-component system response regulator CitB 332840 citB 9796254 citB Arthrobacter arilaitensis Re117 two-component system response regulator CitB YP_003915514.1 332169 D 861360 CDS YP_003915515.1 308176109 9793735 complement(332853..333593) 1 NC_014550.1 match to PF01636. This family consists of bacterial antibiotic resistance proteins, which confer resistance to various aminoglycosides. The aminoglycoside phosphotransferases inactivate aminoglycoside antibiotics via phosphorylation. This family also includes homoserine kinase; phosphotransferase 333593 9793735 AARI_03100 Arthrobacter arilaitensis Re117 phosphotransferase YP_003915515.1 332853 R 861360 CDS YP_003915516.1 308176110 9796255 333732..335339 1 NC_014550.1 catalyses the following reaction : a phosphate monoester + H(2)O <=> an alcohol + phosphate; alkaline phosphatase 335339 9796255 AARI_03110 Arthrobacter arilaitensis Re117 alkaline phosphatase YP_003915516.1 333732 D 861360 CDS YP_003915517.1 308176111 9796256 complement(335410..336696) 1 NC_014550.1 catalyzes the phosphorylation of aspartate. The product of this reaction can then be used in the biosynthesis of lysine or in the pathway leading to homoserine, which participates in the biosynthesis of threonine, isoleucine and methionine; aspartate kinase 336696 ask 9796256 ask Arthrobacter arilaitensis Re117 aspartate kinase YP_003915517.1 335410 R 861360 CDS YP_003915518.1 308176112 9793694 complement(336878..337429) 1 NC_014550.1 hypothetical protein 337429 9793694 AARI_03130 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915518.1 336878 R 861360 CDS YP_003915519.1 308176113 9796257 complement(337450..337605) 1 NC_014550.1 hypothetical protein 337605 9796257 AARI_03140 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915519.1 337450 R 861360 CDS YP_003915520.1 308176114 9796258 complement(337846..338322) 1 NC_014550.1 identified by match to protein family PF01047. Regulators with the marR-type HTH domain are present in bacteria and archaea and control a variety of biological functions, including resistance to multiple antibiotics, household disinfectants, organic solvents, oxidative stress agents and regulation of the virulence factor synthesis in pathogens of humans and plants. Many of the marR-like regulators respond to aromatic compounds; MarR family transcriptional regulator 338322 9796258 AARI_03150 Arthrobacter arilaitensis Re117 MarR family transcriptional regulator YP_003915520.1 337846 R 861360 CDS YP_003915521.1 308176115 9796259 complement(338331..339953) 1 NC_014550.1 major facilitator superfamily, drug:H+ antiporter-2 (14 spanner) (DHA2) family (TC 2.A.1.3.z). Identified by match to protein family TIGR00711; EmrB/QacA subfamily drug resistance transporter 339953 9796259 AARI_03160 Arthrobacter arilaitensis Re117 EmrB/QacA subfamily drug resistance transporter YP_003915521.1 338331 R 861360 CDS YP_003915522.1 308176116 9796260 complement(340137..340949) 1 NC_014550.1 may play a role in DNA repair. It seems to be involved in an recBC-independent recombinational process of DNA repair. It may act with recF and recO; recombination protein recR 340949 recR 9796260 recR Arthrobacter arilaitensis Re117 recombination protein recR YP_003915522.1 340137 R 861360 CDS YP_003915523.1 308176117 9794291 complement(341040..344486) 1 NC_014550.1 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII complex. PolIII associates with the gamma complex (composed of gamma, delta, delta, psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex; DNA polymerase III subunits gamma and tau 344486 dnaX 9794291 dnaX Arthrobacter arilaitensis Re117 DNA polymerase III subunits gamma and tau YP_003915523.1 341040 R 861360 CDS YP_003915524.1 308176118 9793828 complement(344577..345497) 1 NC_014550.1 glutamate--tRNA ligase 345497 9793828 AARI_03190 Arthrobacter arilaitensis Re117 glutamate--tRNA ligase YP_003915524.1 344577 R 861360 CDS YP_003915525.1 308176119 9796261 complement(345728..347260) 1 NC_014550.1 identified by match to cd00085: HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins; HNH endonuclease 347260 9796261 AARI_03200 Arthrobacter arilaitensis Re117 HNH endonuclease YP_003915525.1 345728 R 861360 CDS YP_003915526.1 308176120 9793581 347668..348033 1 NC_014550.1 hypothetical protein 348033 9793581 AARI_03210 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915526.1 347668 D 861360 CDS YP_003915527.1 308176121 9796263 complement(348140..349180) 1 NC_014550.1 identified by match to PF03171. This family contains members of the 2-oxoglutarate (2OG) and Fe(II)- dependent oxygenase superfamily; 2OG-Fe(II) oxygenase superfamily protein 349180 9796263 AARI_03220 Arthrobacter arilaitensis Re117 2OG-Fe(II) oxygenase superfamily protein YP_003915527.1 348140 R 861360 CDS YP_003915528.1 308176122 9796264 349456..349758 1 NC_014550.1 hypothetical protein 349758 9796264 AARI_03230 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915528.1 349456 D 861360 CDS YP_003915529.1 308176123 9796265 349840..350460 1 NC_014550.1 hypothetical protein 350460 9796265 AARI_03240 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915529.1 349840 D 861360 CDS YP_003915530.1 308176124 9796266 complement(350465..351154) 1 NC_014550.1 match to protein domain PF01323; DSBA-like thioredoxin domain-containing protein 351154 9796266 AARI_03250 Arthrobacter arilaitensis Re117 DSBA-like thioredoxin domain-containing protein YP_003915530.1 350465 R 861360 CDS YP_003915531.1 308176125 9796267 351220..351999 1 NC_014550.1 6 transmembrane helices predicted by TMHMM2.0; hypothetical protein 351999 9796267 AARI_03260 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915531.1 351220 D 861360 CDS YP_003915532.1 308176126 9796268 complement(352064..353470) 1 NC_014550.1 amino acid-polyamine-organocation (APC) superfamily, amino acid transporter (AAT) family, histidine permease (TC 2.A.3.1.9). Identified by similarity to protein SP:Q9H86 (Pseudomonas aeruginosa); histidine-specific permease 353470 hutT 9796268 hutT Arthrobacter arilaitensis Re117 histidine-specific permease YP_003915532.1 352064 R 861360 CDS YP_003915533.1 308176127 9793993 353597..354223 1 NC_014550.1 identified by match to protein domain PF00300; phosphoglycerate mutase family protein 354223 9793993 AARI_03280 Arthrobacter arilaitensis Re117 phosphoglycerate mutase family protein YP_003915533.1 353597 D 861360 CDS YP_003915534.1 308176128 9796269 complement(354230..355294) 1 NC_014550.1 match to PF00561: alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes; hydrolase 355294 9796269 AARI_03290 Arthrobacter arilaitensis Re117 hydrolase YP_003915534.1 354230 R 861360 CDS YP_003915535.1 308176129 9796270 complement(355426..357063) 1 NC_014550.1 catalyzes the aldol condensation of glyoxylate with acetyl-CoA to form malate, the second step of the glyoxylate bypass, an alternative to the tricarboxylic acid cycle in bacteria, fungi and plants; malate synthase 357063 aceB 9796270 aceB Arthrobacter arilaitensis Re117 malate synthase YP_003915535.1 355426 R 861360 CDS YP_003915536.1 308176130 9793648 complement(357144..358457) 1 NC_014550.1 catalyzes the conversion of isocitrate to succinate and glyoxylate. This is the first step in the glyoxylate bypass, an alternative to the tricarboxylic acid cycle in bacteria, fungi and plants; isocitrate lyase 358457 aceA 9793648 aceA Arthrobacter arilaitensis Re117 isocitrate lyase YP_003915536.1 357144 R 861360 CDS YP_003915537.1 308176131 9793647 complement(358984..359586) 1 NC_014550.1 hypothetical protein 359586 9793647 AARI_03320 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915537.1 358984 R 861360 CDS YP_003915538.1 308176132 9796271 complement(359596..360216) 1 NC_014550.1 identified by match to protein domain PF02223. dTMP kinase (thymidylate kinase) catalyzes the phosphorylation of thymidine 5-monophosphate (dTMP) to thymidine 5- diphosphate (dTDP) in the presence of ATP and magnesium; dTMP kinase 360216 9796271 AARI_03330 Arthrobacter arilaitensis Re117 dTMP kinase YP_003915538.1 359596 R 861360 CDS YP_003915539.1 308176133 9796353 360294..360392 1 NC_014550.1 hypothetical protein 360392 9796353 AARI_03340 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915539.1 360294 D 861360 CDS YP_003915540.1 308176134 9796354 360453..361916 1 NC_014550.1 match to protein domain PF01381: helix-turn-helix; transcriptional regulator 361916 9796354 AARI_03350 Arthrobacter arilaitensis Re117 transcriptional regulator YP_003915540.1 360453 D 861360 CDS YP_003915541.1 308176135 9796355 complement(361927..362589) 1 NC_014550.1 hydrolase 362589 9796355 AARI_03360 Arthrobacter arilaitensis Re117 hydrolase YP_003915541.1 361927 R 861360 CDS YP_003915542.1 308176136 9796356 complement(362644..363543) 1 NC_014550.1 signal peptide predicted by SignalP 3.0 HMM (probability: 1.000) with cleavage site probability 0.454 between position 41 and 42; hypothetical protein 363543 9796356 AARI_03370 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915542.1 362644 R 861360 CDS YP_003915543.1 308176137 9796357 complement(363603..364022) 1 NC_014550.1 identified by match to PF00583: acetyltransferase (GNAT) family; GNAT family acetyltransferase 364022 9796357 AARI_03380 Arthrobacter arilaitensis Re117 GNAT family acetyltransferase YP_003915543.1 363603 R 861360 CDS YP_003915544.1 308176138 9796358 complement(364052..364408) 1 NC_014550.1 hypothetical protein 364408 9796358 AARI_03390 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915544.1 364052 R 861360 CDS YP_003915545.1 308176139 9796359 complement(364496..364993) 1 NC_014550.1 identified by match to PF00583: acetyltransferase (GNAT) family; GNAT family acetyltransferase 364993 9796359 AARI_03400 Arthrobacter arilaitensis Re117 GNAT family acetyltransferase YP_003915545.1 364496 R 861360 CDS YP_003915546.1 308176140 9796360 complement(365165..367723) 1 NC_014550.1 ATP-dependent Clp proteases act as chaperones to target the proteases to substrates; ATP-dependent Clp protease ATP-binding subunit 367723 clpC 9796360 clpC Arthrobacter arilaitensis Re117 ATP-dependent Clp protease ATP-binding subunit YP_003915546.1 365165 R 861360 CDS YP_003915547.1 308176141 9793739 complement(367853..368527) 1 NC_014550.1 response regulators are key elements in two- component signal transduction systems, which enable bacteria to sense, respond, and adapt to a wide range of environments, stressors, and growth conditions; two-component system response regulator 368527 9793739 AARI_03420 Arthrobacter arilaitensis Re117 two-component system response regulator YP_003915547.1 367853 R 861360 CDS YP_003915548.1 308176142 9796361 368629..368796 1 NC_014550.1 hypothetical protein 368796 9796361 AARI_03430 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915548.1 368629 D 861360 CDS YP_003915549.1 308176143 9796362 368856..370028 1 NC_014550.1 protein-histidine kinases are key elements in two- component signal transduction systems, which enable bacteria to sense, respond, and adapt to a wide range of environments, stressors, and growth conditions. 5 transmembrane helices predicted by TMHMM2.0; signal transduction histidine kinase 370028 9796362 AARI_03440 Arthrobacter arilaitensis Re117 signal transduction histidine kinase YP_003915549.1 368856 D 861360 CDS YP_003915550.1 308176144 9796363 370382..371002 1 NC_014550.1 dihydropteridine reductase family protein 371002 9796363 AARI_03450 Arthrobacter arilaitensis Re117 dihydropteridine reductase family protein YP_003915550.1 370382 D 861360 CDS YP_003915551.1 308176145 9796364 complement(371071..372276) 1 NC_014550.1 hypothetical protein 372276 9796364 AARI_03460 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915551.1 371071 R 861360 CDS YP_003915552.1 308176146 9796365 372582..373877 1 NC_014550.1 catalyzes the following reaction: D-amino acid + H(2)O + acceptor <=> 2-oxo acid + NH(3) + reduced acceptor. Acts to some extent on all D-amino acids except D-aspartate and D-glutamate; D-amino-acid dehydrogenase 373877 9796365 AARI_03470 Arthrobacter arilaitensis Re117 D-amino-acid dehydrogenase YP_003915552.1 372582 D 861360 CDS YP_003915553.1 308176147 9796366 374204..375511 1 NC_014550.1 transposase of ISAar23, ISL3 family 375511 9796366 AARI_34450 Arthrobacter arilaitensis Re117 transposase of ISAar23, ISL3 family YP_003915553.1 374204 D 861360 CDS YP_003915554.1 308176148 9797147 complement(375571..376425) 1 NC_014550.1 identified by match to protein family PF01370: NAD dependent epimerase/dehydratase family. This family of proteins utilise NAD as a cofactor. The proteins in this family use nucleotide-sugar substrates for a variety of chemical reactions; NAD dependent epimerase/dehydratase family protein 376425 9797147 AARI_03480 Arthrobacter arilaitensis Re117 NAD dependent epimerase/dehydratase family protein YP_003915554.1 375571 R 861360 CDS YP_003915555.1 308176149 9796367 376541..377746 1 NC_014550.1 major facilitator superfamily (TC 2.A.1.y.z). Identified by match to protein family PF07690 (Major Facilitator Superfamily); MFS superfamily transporter 377746 9796367 AARI_03490 Arthrobacter arilaitensis Re117 MFS superfamily transporter YP_003915555.1 376541 D 861360 CDS YP_003915556.1 308176150 9796368 378017..378433 1 NC_014550.1 in Escherichia coli umuD and umuC genes have been shown to encode E. coli s fifth DNA polymerase, pol V (consisting of a heterotrimer of UmuD (2)C). The main function of pol V appears to be the bypass of DNA lesions that would otherwise block replication by pols I-IV; DNA polymerase subunit UmuD 378433 umuD 9796368 umuD Arthrobacter arilaitensis Re117 DNA polymerase subunit UmuD YP_003915556.1 378017 D 861360 CDS YP_003915557.1 308176151 9794488 378423..379715 1 NC_014550.1 in Escherichia coli umuD and umuC genes have been shown to encode E. coli s fifth DNA polymerase, pol V (consisting of a heterotrimer of UmuD (2)C). The main function of pol V appears to be the bypass of DNA lesions that would otherwise block replication by pols I-IV; DNA polymerase subunit UmuC 379715 umuC 9794488 umuC Arthrobacter arilaitensis Re117 DNA polymerase subunit UmuC YP_003915557.1 378423 D 861360 CDS YP_003915558.1 308176152 9794487 379788..381107 1 NC_014550.1 identified by match to PF00933. Glycoside hydrolase family 3 comprises enzymes with a number of known activities; beta-glucosidase (EC:3.2.1.21); beta- xylosidase (EC:3.2.1.37); N-acetyl beta-glucosaminidase (EC:3.2.1.52); glucan beta-1,3-glucosidase (EC:3.2.1.58); cellodextrinase (EC:3.2.1.74); exo-1,3-1,4-glucanase (EC:3. 2.1); glycosyl hydrolase family 3 protein 381107 9794487 AARI_03520 Arthrobacter arilaitensis Re117 glycosyl hydrolase family 3 protein YP_003915558.1 379788 D 861360 CDS YP_003915559.1 308176153 9796369 complement(381145..384426) 1 NC_014550.1 identified by match to PF00082. Subtilases are a family of serine proteases. The vast majority of the family are endopeptidases. Signal peptide predicted by SignalP 3.0 HMM (probability: 1.000) with cleavage site probability 0.964 between position 32 and 33; subtilase 384426 9796369 AARI_03530 Arthrobacter arilaitensis Re117 subtilase YP_003915559.1 381145 R 861360 CDS YP_003915560.1 308176154 9796370 complement(384780..385268) 1 NC_014550.1 hypothetical protein 385268 9796370 AARI_03540 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915560.1 384780 R 861360 CDS YP_003915561.1 308176155 9796371 385681..386958 1 NC_014550.1 transposase of ISAar13, ISL3 family 386958 9796371 AARI_34460 Arthrobacter arilaitensis Re117 transposase of ISAar13, ISL3 family YP_003915561.1 385681 D 861360 CDS YP_003915562.1 308176156 9797148 complement(387055..387876) 1 NC_014550.1 EC 2.7.4.7 is involved in thiamin biosynthesis. It catalyzes the phosphorylation of HMP-P to HMP-PP; phosphomethylpyrimidine kinase 387876 9797148 AARI_03550 Arthrobacter arilaitensis Re117 phosphomethylpyrimidine kinase YP_003915562.1 387055 R 861360 CDS YP_003915563.1 308176157 9796372 complement(387918..388532) 1 NC_014550.1 hypothetical protein 388532 9796372 AARI_03560 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915563.1 387918 R 861360 CDS YP_003915564.1 308176158 9796373 complement(388666..389373) 1 NC_014550.1 identified by match to PF00440: bacterial regulatory proteins, tetR family; TetR family transcriptional regulator 389373 9796373 AARI_03570 Arthrobacter arilaitensis Re117 TetR family transcriptional regulator YP_003915564.1 388666 R 861360 CDS YP_003915565.1 308176159 9796374 389732..390442 1 NC_014550.1 6 transmembrane helices predicted by TMHMM2.0; hypothetical protein 390442 9796374 AARI_03580 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915565.1 389732 D 861360 CDS YP_003915566.1 308176160 9796375 390509..391204 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily (TC 3. A.1.y.z). ABCISSE: ABC transporter, ATP-binding protein (ABC), DRI-family; ABC transporter ATP-binding subunit 391204 9796375 AARI_03590 Arthrobacter arilaitensis Re117 ABC transporter ATP-binding subunit YP_003915566.1 390509 D 861360 CDS YP_003915567.1 308176161 9796376 391212..392777 1 NC_014550.1 12 transmembrane helices predicted by TMHMM2.0; hypothetical protein 392777 9796376 AARI_03600 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915567.1 391212 D 861360 CDS YP_003915568.1 308176162 9796377 392806..393261 1 NC_014550.1 identified by match to PF00583: acetyltransferase (GNAT) family; GNAT family acetyltransferase 393261 9796377 AARI_03610 Arthrobacter arilaitensis Re117 GNAT family acetyltransferase YP_003915568.1 392806 D 861360 CDS YP_003915569.1 308176163 9796378 complement(393333..394631) 1 NC_014550.1 exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)- 7-deazaguanosine); queuine tRNA-ribosyltransferase 394631 tgt 9796378 tgt Arthrobacter arilaitensis Re117 queuine tRNA-ribosyltransferase YP_003915569.1 393333 R 861360 CDS YP_003915570.1 308176164 9794438 394765..395862 1 NC_014550.1 10 transmembrane helices predicted by TMHMM2.0; hypothetical protein 395862 9794438 AARI_03630 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915570.1 394765 D 861360 CDS YP_003915571.1 308176165 9796379 complement(395859..396398) 1 NC_014550.1 hypothetical protein 396398 9796379 AARI_03640 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915571.1 395859 R 861360 CDS YP_003915572.1 308176166 9796380 396607..398055 1 NC_014550.1 major facilitator superfamily, drug:H+ antiporter-2 (14 spanner) (DHA2) family (TC 2.A.1.3.z). Identified by match to protein family TIGR00711; EmrB/QacA subfamily drug resistance transporter 398055 9796380 AARI_03650 Arthrobacter arilaitensis Re117 EmrB/QacA subfamily drug resistance transporter YP_003915572.1 396607 D 861360 CDS YP_003915573.1 308176167 9796381 398204..398980 1 NC_014550.1 identified by match to PF00106. The short-chain dehydrogenases/reductases family (SDR) is a very large family of enzymes, most of which are known to be NAD- or NADP-dependent oxidoreductases; short-chain dehydrogenases/reductase 398980 9796381 AARI_03660 Arthrobacter arilaitensis Re117 short-chain dehydrogenases/reductase YP_003915573.1 398204 D 861360 CDS YP_003915574.1 308176168 9796382 complement(399005..399421) 1 NC_014550.1 4 transmembrane helices predicted by TMHMM2.0; hypothetical protein 399421 9796382 AARI_03670 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915574.1 399005 R 861360 CDS YP_003915575.1 308176169 9796383 399461..401104 1 NC_014550.1 serine recombinases demonstrate functional versatility and include resolvases, invertases, integrases, and transposases. This protein may be a resolvase (match to PF07508 and PF00239); site-specific recombinase 401104 9796383 AARI_03680 Arthrobacter arilaitensis Re117 site-specific recombinase YP_003915575.1 399461 D 861360 CDS YP_003915576.1 308176170 9796384 complement(401281..401850) 1 NC_014550.1 hypothetical protein 401850 9796384 AARI_03690 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915576.1 401281 R 861360 CDS YP_003915577.1 308176171 9796385 complement(401860..402321) 1 NC_014550.1 identified by match to PF00436. The Escherichia coli single-strand binding protein binds tightly to single- stranded DNA (ss-DNA) and plays an important role in DNA replication, recombination and repair. Closely related variants of SSB are encoded in the genome of a variety of large self-transmissible plasmids; single-stranded DNA-binding protein 402321 9796385 AARI_03700 Arthrobacter arilaitensis Re117 single-stranded DNA-binding protein YP_003915577.1 401860 R 861360 CDS YP_003915578.1 308176172 9796386 complement(402407..404173) 1 NC_014550.1 3 transmembrane helices predicted by TMHMM2.0; hypothetical protein 404173 9796386 AARI_03710 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915578.1 402407 R 861360 CDS YP_003915579.1 308176173 9796387 complement(404170..404709) 1 NC_014550.1 hypothetical protein 404709 9796387 AARI_03720 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915579.1 404170 R 861360 CDS YP_003915580.1 308176174 9796388 complement(404706..406262) 1 NC_014550.1 hypothetical protein 406262 9796388 AARI_03730 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915580.1 404706 R 861360 CDS YP_003915581.1 308176175 9796389 complement(406259..407074) 1 NC_014550.1 hypothetical protein 407074 9796389 AARI_03740 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915581.1 406259 R 861360 CDS YP_003915582.1 308176176 9796390 407333..409069 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, () drug resistance ATPase-1 (Drug RA1) family (TC 3.A.1.120.z). ABCISSE: fused ATP-binding protein (ABC2), ART-family. Duplicated ATPase domains (PF00005); drug resistance ATP-binding protein 409069 9796390 AARI_03750 Arthrobacter arilaitensis Re117 drug resistance ATP-binding protein YP_003915582.1 407333 D 861360 CDS YP_003915583.1 308176177 9796391 complement(409105..410085) 1 NC_014550.1 identified by match to PF08240. Zn-dependent alcohol dehydrogenases catalyse the following reaction: an alcohol + NAD(+) <=> an aldehyde or ketone + NADH; Zn-dependent alcohol dehydrogenase 410085 9796391 AARI_03760 Arthrobacter arilaitensis Re117 Zn-dependent alcohol dehydrogenase YP_003915583.1 409105 R 861360 CDS YP_003915584.1 308176178 9796392 complement(410151..411626) 1 NC_014550.1 2 transmembrane helices predicted by TMHMM2.0; hypothetical protein 411626 9796392 AARI_03770 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915584.1 410151 R 861360 CDS YP_003915585.1 308176179 9796393 complement(411633..413063) 1 NC_014550.1 7 transmembrane helices predicted by TMHMM2.0; hypothetical protein 413063 9796393 AARI_03780 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915585.1 411633 R 861360 CDS YP_003915586.1 308176180 9796394 complement(413107..413466) 1 NC_014550.1 match to PS00430: TonB-dependent receptor proteins signature. In Escherichia coli the TonB protein interacts with outer membrane receptor proteins that carry out high- affinity binding and energy-dependent uptake of specific substrates into the periplasmic space. 2 transmembrane helices predicted by TMHMM2.0; TonB-box containing protein 413466 9796394 AARI_03790 Arthrobacter arilaitensis Re117 TonB-box containing protein YP_003915586.1 413107 R 861360 CDS YP_003915587.1 308176181 9796395 413569..414174 1 NC_014550.1 identified by match to protein domain PF08241; SAM-dependent methyltransferase 414174 9796395 AARI_03800 Arthrobacter arilaitensis Re117 SAM-dependent methyltransferase YP_003915587.1 413569 D 861360 CDS YP_003915588.1 308176182 9796396 complement(414175..414441) 1 NC_014550.1 hypothetical protein 414441 9796396 AARI_03810 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915588.1 414175 R 861360 CDS YP_003915589.1 308176183 9796397 complement(414444..416066) 1 NC_014550.1 identified by match to protein family PF01551. Members of this family are zinc metallopeptidases with a range of specificities. Peptidase family M23 are also endopeptidases. Signal peptide predicted by SignalP 3.0 HMM (probability: 1.000) with cleavage site probability 0. 740 between position 37 and 38; peptidase M23 416066 9796397 AARI_03820 Arthrobacter arilaitensis Re117 peptidase M23 YP_003915589.1 414444 R 861360 CDS YP_003915590.1 308176184 9796398 complement(416073..416720) 1 NC_014550.1 1 transmembrane helice predicted by TMHMM2.0; hypothetical protein 416720 9796398 AARI_03830 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915590.1 416073 R 861360 CDS YP_003915591.1 308176185 9796399 complement(416796..417902) 1 NC_014550.1 match to protein family PF02195. Proteins containing this domain, appear to be related to the Escherichia coli plasmid protein ParB, which preferentially cleaves single-stranded DNA; ParB-like protein 417902 9796399 AARI_03840 Arthrobacter arilaitensis Re117 ParB-like protein YP_003915591.1 416796 R 861360 CDS YP_003915592.1 308176186 9796400 complement(417886..418812) 1 NC_014550.1 hypothetical protein 418812 9796400 AARI_03850 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915592.1 417886 R 861360 CDS YP_003915593.1 308176187 9796401 complement(418819..419253) 1 NC_014550.1 hypothetical protein 419253 9796401 AARI_03860 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915593.1 418819 R 861360 CDS YP_003915594.1 308176188 9796402 complement(419250..419981) 1 NC_014550.1 similar to excisionases from Mycobacterium phages; phage excisionase 419981 9796402 AARI_03870 Arthrobacter arilaitensis Re117 phage excisionase YP_003915594.1 419250 R 861360 CDS YP_003915595.1 308176189 9796403 complement(419978..420883) 1 NC_014550.1 match to protein family PF09250; bifunctional primase/DNA polymerase protein 420883 9796403 AARI_03880 Arthrobacter arilaitensis Re117 bifunctional primase/DNA polymerase protein YP_003915595.1 419978 R 861360 CDS YP_003915596.1 308176190 9796404 complement(420885..421976) 1 NC_014550.1 hypothetical protein 421976 9796404 AARI_03890 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915596.1 420885 R 861360 CDS YP_003915597.1 308176191 9796405 complement(422211..423167) 1 NC_014550.1 identified by match to protein domain PF00165: bacterial regulatory helix-turn-helix proteins, AraC family; AraC family transcriptional regulator 423167 9796405 AARI_03900 Arthrobacter arilaitensis Re117 AraC family transcriptional regulator YP_003915597.1 422211 R 861360 CDS YP_003915598.1 308176192 9796406 complement(423172..424479) 1 NC_014550.1 major facilitator superfamily (TC 2.A.1.y.z). Identified by match to protein family PF07690; MFS superfamily transporter 424479 9796406 AARI_03910 Arthrobacter arilaitensis Re117 MFS superfamily transporter YP_003915598.1 423172 R 861360 CDS YP_003915599.1 308176193 9796407 complement(424558..426144) 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, siderophore-Fe3+ uptake transporter (SIUT) family (TC 3.A. 1.21.z). ABCISSE: ABC transporter, permease and ATP- binding protein (IM-ABC), DPL-family, SID-subfamily (siderophore uptake); iron-siderophore ABC transporter ATPase and permease components 426144 9796407 AARI_03920 Arthrobacter arilaitensis Re117 iron-siderophore ABC transporter ATPase and permease components YP_003915599.1 424558 R 861360 CDS YP_003915600.1 308176194 9796408 complement(426141..427748) 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, siderophore-Fe3+ uptake transporter (SIUT) family (TC 3.A. 1.21.z). ABCISSE: ABC transporter, permease and ATP- binding protein (IM-ABC), DPL-family, SID-subfamily (siderophore uptake); iron-siderophore ABC transporter ATPase and permease components 427748 9796408 AARI_03930 Arthrobacter arilaitensis Re117 iron-siderophore ABC transporter ATPase and permease components YP_003915600.1 426141 R 861360 CDS YP_003915601.1 308176195 9796409 complement(427748..428623) 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, iron chelate uptake transporter (FeCT) family (TC 3.A.1.14.z). ABCISSE: ABC transporter, ATP-binding protein (ABC), ISVH- family (iron siderophores, vitamin B12 and hemin); iron-siderophore ABC transporter ATP-binding subunit 428623 9796409 AARI_03940 Arthrobacter arilaitensis Re117 iron-siderophore ABC transporter ATP-binding subunit YP_003915601.1 427748 R 861360 CDS YP_003915602.1 308176196 9796410 complement(428629..429708) 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, iron chelate uptake transporter (FeCT) family (TC 3.A.1.14.z). ABCISSE: ABC transporter, permease (IM), ISVH-family (iron siderophores, vitamin B12 and hemin); iron-siderophore ABC transporter inner membrane subunit 429708 9796410 AARI_03950 Arthrobacter arilaitensis Re117 iron-siderophore ABC transporter inner membrane subunit YP_003915602.1 428629 R 861360 CDS YP_003915603.1 308176197 9796411 complement(429705..430670) 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, iron chelate uptake transporter (FeCT) family (TC 3.A.1.14.z). ABCISSE: ABC transporter, binding protein (BP), ISVH- family (iron siderophores, vitamin B12 and hemin); iron-siderophore ABC transporter substrate-binding protein 430670 9796411 AARI_03960 Arthrobacter arilaitensis Re117 iron-siderophore ABC transporter substrate-binding protein YP_003915603.1 429705 R 861360 CDS YP_003915604.1 308176198 9796412 complement(430844..431908) 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, iron chelate uptake transporter (FeCT) family (TC 3.A.1.14.z). ABCISSE: ABC transporter, binding protein (BP), ISVH- family (iron siderophores, vitamin B12 and hemin); iron-siderophore ABC transporter substrate-binding protein 431908 9796412 AARI_03970 Arthrobacter arilaitensis Re117 iron-siderophore ABC transporter substrate-binding protein YP_003915604.1 430844 R 861360 CDS YP_003915605.1 308176199 9796413 complement(431953..433041) 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, iron chelate uptake transporter (FeCT) family (TC 3.A.1.14.z). ABCISSE: ABC transporter, binding protein (BP), ISVH- family (iron siderophores, vitamin B12 and hemin); iron-siderophore ABC transporter substrate-binding protein 433041 9796413 AARI_03980 Arthrobacter arilaitensis Re117 iron-siderophore ABC transporter substrate-binding protein YP_003915605.1 431953 R 861360 CDS YP_003915606.1 308176200 9796414 complement(433038..434225) 1 NC_014550.1 major facilitator superfamily (TC 2.A.1.y.z). Identified by match to protein family PF07690; MFS superfamily transporter 434225 9796414 AARI_03990 Arthrobacter arilaitensis Re117 MFS superfamily transporter YP_003915606.1 433038 R 861360 CDS YP_003915607.1 308176201 9796415 complement(434316..435137) 1 NC_014550.1 identified by match to protein family PF04954. Match to protein domain PF08021. Possibly involved in removal of iron from iron-siderophore complexes; siderophore-interacting protein 435137 9796415 AARI_04000 Arthrobacter arilaitensis Re117 siderophore-interacting protein YP_003915607.1 434316 R 861360 CDS YP_003915608.1 308176202 9796416 435302..436891 1 NC_014550.1 identified by match to protein domain PF00165: bacterial regulatory helix-turn-helix proteins, AraC family; AraC family transcriptional regulator 436891 9796416 AARI_04010 Arthrobacter arilaitensis Re117 AraC family transcriptional regulator YP_003915608.1 435302 D 861360 CDS YP_003915609.1 308176203 9796417 complement(436993..438168) 1 NC_014550.1 C-5 cytosine-specific DNA methylases are enzymes that specifically methylate the C-5 carbon of cytosines in DNA. They are found as a component of type II restriction- modification systems in prokaryotes and some bacteriophages; DNA (cytosine-5-)-methyltransferase 438168 9796417 AARI_04020 Arthrobacter arilaitensis Re117 DNA (cytosine-5-)-methyltransferase YP_003915609.1 436993 R 861360 CDS YP_003915610.1 308176204 9796418 438399..441944 1 NC_014550.1 match to PF08751: TrwC relaxase. Similar to proteins involved in the conjugal tranfer of plasmids; conjugal transfer protein 441944 9796418 AARI_04030 Arthrobacter arilaitensis Re117 conjugal transfer protein YP_003915610.1 438399 D 861360 CDS YP_003915611.1 308176205 9796419 complement(442008..443009) 1 NC_014550.1 the SMF family (DNA processing chain A, dprA) are a group of bacterial proteins. In Helicobacter pylori, dprA is required for natural chromosomal and plasmid transformation; smf family protein 443009 9796419 AARI_04040 Arthrobacter arilaitensis Re117 smf family protein YP_003915611.1 442008 R 861360 CDS YP_003915612.1 308176206 9796420 complement(443069..443413) 1 NC_014550.1 2 transmembrane helices predicted by TMHMM2.0; hypothetical protein 443413 9796420 AARI_04050 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915612.1 443069 R 861360 CDS YP_003915613.1 308176207 9797150 445497..446579 1 NC_014550.1 match to protein family PF00589. Possible phage integrase or tyrosine recombinase subunit; phage integrase family protein 446579 9797150 AARI_04070 Arthrobacter arilaitensis Re117 phage integrase family protein YP_003915613.1 445497 D 861360 CDS YP_003915614.1 308176208 9796423 446671..448464 1 NC_014550.1 match to protein family PF00589. Possible phage integrase or tyrosine recombinase subunit; phage integrase family protein 448464 9796423 AARI_04080 Arthrobacter arilaitensis Re117 phage integrase family protein YP_003915614.1 446671 D 861360 CDS YP_003915615.1 308176209 9796424 448461..448769 1 NC_014550.1 hypothetical protein 448769 9796424 AARI_04090 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915615.1 448461 D 861360 CDS YP_003915616.1 308176210 9796426 complement(449892..450773) 1 NC_014550.1 6 transmembrane helices predicted by TMHMM2.0; hypothetical protein 450773 9796426 AARI_04110 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915616.1 449892 R 861360 CDS YP_003915617.1 308176211 9796427 complement(450770..451483) 1 NC_014550.1 TC 3.A.1.y.z. ABCISSE: ABC transporter, ATP-binding protein (ABC), DRI-family, DRB-subfamily (drug resistance, ). Possible function in drug efflux; drug resistance ATP-binding protein 451483 9796427 AARI_04120 Arthrobacter arilaitensis Re117 drug resistance ATP-binding protein YP_003915617.1 450770 R 861360 CDS YP_003915618.1 308176212 9796428 complement(451486..452190) 1 NC_014550.1 5 transmembrane helices predicted by TMHMM2.0; hypothetical protein 452190 9796428 AARI_04130 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915618.1 451486 R 861360 CDS YP_003915619.1 308176213 9796429 452342..453586 1 NC_014550.1 protein-histidine kinases are key elements in two- component signal transduction systems, which enable bacteria to sense, respond, and adapt to a wide range of environments, stressors, and growth conditions. 6 transmembrane helices predicted by TMHMM2.0; signal transduction histidine kinase 453586 9796429 AARI_04140 Arthrobacter arilaitensis Re117 signal transduction histidine kinase YP_003915619.1 452342 D 861360 CDS YP_003915620.1 308176214 9796430 453583..454257 1 NC_014550.1 response regulators are key elements in two- component signal transduction systems, which enable bacteria to sense, respond, and adapt to a wide range of environments, stressors, and growth conditions; two-component system response regulator 454257 9796430 AARI_04150 Arthrobacter arilaitensis Re117 two-component system response regulator YP_003915620.1 453583 D 861360 CDS YP_003915621.1 308176215 9796431 454254..454814 1 NC_014550.1 2 transmembrane helices predicted by TMHMM2.0; hypothetical protein 454814 9796431 AARI_04160 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915621.1 454254 D 861360 CDS YP_003915622.1 308176216 9796432 complement(455296..455838) 1 NC_014550.1 hypothetical protein 455838 9796432 AARI_04170 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915622.1 455296 R 861360 CDS YP_003915623.1 308176217 9796433 complement(455835..456035) 1 NC_014550.1 hypothetical protein 456035 9796433 AARI_04180 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915623.1 455835 R 861360 CDS YP_003915624.1 308176218 9796515 complement(456087..456707) 1 NC_014550.1 4 transmembrane helices predicted by TMHMM2.0; hypothetical protein 456707 9796515 AARI_04190 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915624.1 456087 R 861360 CDS YP_003915625.1 308176219 9796516 complement(456750..457802) 1 NC_014550.1 identified by match to protein family PF00849. Pseudouridylate synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5- ribosyluracil, psi); pseudouridylate synthase 457802 9796516 AARI_04200 Arthrobacter arilaitensis Re117 pseudouridylate synthase YP_003915625.1 456750 R 861360 CDS YP_003915626.1 308176220 9796517 457863..458699 1 NC_014550.1 identified by match to protein family PF02567. PhzC/PhzF is involved in dimerisation of two 2, 3-dihydro-3- oxo-anthranilic acid molecules to create phenazine-1- carboxylic acid (PCA) by P. fluorescens. This family also contains a thymidilate synthase from Mycobacterium tuberculosis. Many phenazine compounds are found in nature and are produced by bacteria such as Pseudomonas spp., Streptomyces spp., and Pantoea agglomerans. These compounds have been implicated in the virulence and competitive fitness of producing organisms. For example, the phenazine pyocyanin produced by Pseudomonas aeruginosa contributes to its ability to colonise the lungs of cystic fibrosis patients. Similarly, phenazine-1-carboxylic acid, produced by a number of Pseudomonas, increases survival in soil environments and has been shown to be essential for the biological control activity of certain strains; phenazine biosynthesis protein PhzC/PhzF 458699 9796517 AARI_04210 Arthrobacter arilaitensis Re117 phenazine biosynthesis protein PhzC/PhzF YP_003915626.1 457863 D 861360 CDS YP_003915627.1 308176221 9796518 complement(458721..459545) 1 NC_014550.1 involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases; DNA glycosylase 459545 nei 9796518 nei Arthrobacter arilaitensis Re117 DNA glycosylase YP_003915627.1 458721 R 861360 CDS YP_003915628.1 308176222 9794138 complement(459570..464234) 1 NC_014550.1 may be involved in DNA repair; ATP-dependent DNA helicase 464234 9794138 AARI_04230 Arthrobacter arilaitensis Re117 ATP-dependent DNA helicase YP_003915628.1 459570 R 861360 CDS YP_003915629.1 308176223 9796519 complement(464274..464576) 1 NC_014550.1 match to protein domain IPR011991: winged helix repressor DNA-binding; transcriptional regulator 464576 9796519 AARI_04240 Arthrobacter arilaitensis Re117 transcriptional regulator YP_003915629.1 464274 R 861360 CDS YP_003915630.1 308176224 9796520 complement(464560..465021) 1 NC_014550.1 4 transmembrane helices predicted by TMHMM2.0; hypothetical protein 465021 9796520 AARI_04250 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915630.1 464560 R 861360 CDS YP_003915631.1 308176225 9796521 complement(465026..465490) 1 NC_014550.1 3 transmembrane helices predicted by TMHMM2.0; hypothetical protein 465490 9796521 AARI_04260 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915631.1 465026 R 861360 CDS YP_003915632.1 308176226 9796522 complement(465554..466012) 1 NC_014550.1 hypothetical protein 466012 9796522 AARI_04270 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915632.1 465554 R 861360 CDS YP_003915633.1 308176227 9796523 466076..466789 1 NC_014550.1 PAP2 family protein 466789 9796523 AARI_04280 Arthrobacter arilaitensis Re117 PAP2 family protein YP_003915633.1 466076 D 861360 CDS YP_003915634.1 308176228 9796524 complement(466758..467729) 1 NC_014550.1 D-isomer specific 2-hydroxyacid dehydrogenase family protein 467729 9796524 AARI_04290 Arthrobacter arilaitensis Re117 D-isomer specific 2-hydroxyacid dehydrogenase family protein YP_003915634.1 466758 R 861360 CDS YP_003915635.1 308176229 9796525 complement(467826..469673) 1 NC_014550.1 match to PF00149. The metallophosphoesterase motif is found in a large number of proteins invoved in phosphorylation. These include Ser/Thr phosphatases, DNA polymerase, exonucleases, and other phosphatases; metallophosphoesterase 469673 9796525 AARI_04300 Arthrobacter arilaitensis Re117 metallophosphoesterase YP_003915635.1 467826 R 861360 CDS YP_003915636.1 308176230 9796526 469854..470981 1 NC_014550.1 hypothetical protein 470981 9796526 AARI_04310 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915636.1 469854 D 861360 CDS YP_003915637.1 308176231 9796527 471031..471462 1 NC_014550.1 match to protein domain PF03061: thioesterase superfamily; thioesterase family domain-containing protein 471462 9796527 AARI_04320 Arthrobacter arilaitensis Re117 thioesterase family domain-containing protein YP_003915637.1 471031 D 861360 CDS YP_003915638.1 308176232 9796530 472554..473849 1 NC_014550.1 benzoate:H+ symporter (BenE) family, benzoate permease (TC 2.A.46.1.1). Identified by match to protein family PF03594; benzoate permease 473849 9796530 AARI_04350 Arthrobacter arilaitensis Re117 benzoate permease YP_003915638.1 472554 D 861360 CDS YP_003915639.1 308176233 9796531 473971..474762 1 NC_014550.1 catalyzes the first step in NAD biosynthesis from aspartate. Specifically catalyzes the NAD or NADP- dependent dehydrogenation of L-aspartate to iminoaspartate; aspartate dehydrogenase 474762 9796531 AARI_04360 Arthrobacter arilaitensis Re117 aspartate dehydrogenase YP_003915639.1 473971 D 861360 CDS YP_003915640.1 308176234 9796532 complement(474779..475186) 1 NC_014550.1 involved in protocatechuate catabolism; 4-carboxymuconolactone decarboxylase 475186 pcaC 9796532 pcaC Arthrobacter arilaitensis Re117 4-carboxymuconolactone decarboxylase YP_003915640.1 474779 R 861360 CDS YP_003915641.1 308176235 9794181 complement(475205..475975) 1 NC_014550.1 3-oxoadipate enol-lactonase catalyses the formation of 3-oxoadipate from 3-oxoadipate enol-lactone. It is involved in aromatic acids catabolism; 3-oxoadipate enol-lactonase 475975 pcaD 9794181 pcaD Arthrobacter arilaitensis Re117 3-oxoadipate enol-lactonase YP_003915641.1 475205 R 861360 CDS YP_003915642.1 308176236 9794182 complement(475984..477390) 1 NC_014550.1 catalyses the cyclization of 3-carboxy-cis,cis- muconate to 4-carboxy-muconolactone. Involved in aromatic acids catabolism; 3-carboxy-cis,cis-muconate cycloisomerase 477390 pcaB 9794182 pcaB Arthrobacter arilaitensis Re117 3-carboxy-cis,cis-muconate cycloisomerase YP_003915642.1 475984 R 861360 CDS YP_003915643.1 308176237 9794180 complement(477536..478114) 1 NC_014550.1 catalyses the following reaction: 3,4- dihydroxybenzoate + O(2) <=> 3-carboxy-cis,cis-muconate; protocatechuate 3,4-dioxygenase subunit alpha 478114 pcaG 9794180 pcaG Arthrobacter arilaitensis Re117 protocatechuate 3,4-dioxygenase subunit alpha YP_003915643.1 477536 R 861360 CDS YP_003915644.1 308176238 9794183 complement(478116..478964) 1 NC_014550.1 catalyses the following reaction: 3,4- dihydroxybenzoate + O(2) <=> 3-carboxy-cis,cis-muconate; protocatechuate 3,4-dioxygenase subunit beta 478964 pcaH 9794183 pcaH Arthrobacter arilaitensis Re117 protocatechuate 3,4-dioxygenase subunit beta YP_003915644.1 478116 R 861360 CDS YP_003915645.1 308176239 9794184 complement(479005..480201) 1 NC_014550.1 catalyses the following reaction: 4-hydroxybenzoate + NADPH + O(2) <=> protocatechuate + NADP(+) + H(2)O; 4-hydroxybenzoate 3-monooxygenase 480201 pobA 9794184 pobA Arthrobacter arilaitensis Re117 4-hydroxybenzoate 3-monooxygenase YP_003915645.1 479005 R 861360 CDS YP_003915646.1 308176240 9794212 complement(480419..481165) 1 NC_014550.1 identified by match to PF09339: IclR helix-turn- helix domain. This family of bacterial transcriptional regulators groups several proteins, including gylR, a possible activator protein for the gylABX glycerol operon in Streptomyces, and iclR, the repressor of the acetate operon (also known as glyoxylate bypass operon) in Escherichia coli and Salmonella typhimurium; IclR family transcriptional regulator 481165 9794212 AARI_04430 Arthrobacter arilaitensis Re117 IclR family transcriptional regulator YP_003915646.1 480419 R 861360 CDS YP_003915647.1 308176241 9796533 481414..482082 1 NC_014550.1 signal peptide predicted by SignalP 3.0 HMM (probability: 1.000) with cleavage site probability 0.321 between position 26 and 27; hypothetical protein 482082 9796533 AARI_04440 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915647.1 481414 D 861360 CDS YP_003915648.1 308176242 9796534 482258..483469 1 NC_014550.1 acetyl-CoA C-acyltransferase (also named 3-ketoacyl- CoA thiolase or thiolase I) has a broad chain-length specificity for its substrates and is involved in degradative pathways such as fatty acid beta-oxidation; acetyl-CoA C-acyltransferase 483469 9796534 AARI_04450 Arthrobacter arilaitensis Re117 acetyl-CoA C-acyltransferase YP_003915648.1 482258 D 861360 CDS YP_003915649.1 308176243 9796535 483489..484160 1 NC_014550.1 identified by similarity to protein SP:Q01103 (Pseudomonas putida). Catalyses the following reaction : succinyl-CoA + 3-oxoadipate = succinate + 3-oxoadipyl-CoA; 3-oxoadipate CoA-transferase subunit A 484160 pcaI 9796535 pcaI Arthrobacter arilaitensis Re117 3-oxoadipate CoA-transferase subunit A YP_003915649.1 483489 D 861360 CDS YP_003915650.1 308176244 9794185 484160..484807 1 NC_014550.1 identified by similarity to protein SP: P0A102 (Pseudomonas putida). Catalyses the following reaction : succinyl-CoA + 3-oxoadipate = succinate + 3-oxoadipyl-CoA; 3-oxoadipate CoA-transferase subunit B 484807 pcaJ 9794185 pcaJ Arthrobacter arilaitensis Re117 3-oxoadipate CoA-transferase subunit B YP_003915650.1 484160 D 861360 CDS YP_003915651.1 308176245 9794186 484829..485671 1 NC_014550.1 identified by match to PF09339: IclR helix-turn- helix domain. This family of bacterial transcriptional regulators groups several proteins, including gylR, a possible activator protein for the gylABX glycerol operon in Streptomyces, and iclR, the repressor of the acetate operon (also known as glyoxylate bypass operon) in Escherichia coli and Salmonella typhimurium; IclR family transcriptional regulator 485671 9794186 AARI_04480 Arthrobacter arilaitensis Re117 IclR family transcriptional regulator YP_003915651.1 484829 D 861360 CDS YP_003915652.1 308176246 9796536 complement(485760..486152) 1 NC_014550.1 match to protein domain IPR011588: glyoxalase/extradiol ring-cleavage dioxygenase domain; hypothetical protein 486152 9796536 AARI_04490 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915652.1 485760 R 861360 CDS YP_003915653.1 308176247 9796537 complement(486247..487128) 1 NC_014550.1 triacylglycerol lipase hydrolyzes ester bonds in triacylglycerol giving diacylglycerol, monoacylglycerol, glycerol and free fatty acids. Signal peptide predicted by SignalP 3.0 HMM (probability: 1) with cleavage site probability 0.991 between position 34 and 35; triacylglycerol lipase 487128 9796537 AARI_04500 Arthrobacter arilaitensis Re117 triacylglycerol lipase YP_003915653.1 486247 R 861360 CDS YP_003915654.1 308176248 9796538 487599..488249 1 NC_014550.1 identified by match to protein family PF02230. This family consists of both phospholipases and carboxylesterases with broad substrate specificity; phospholipase/carboxylesterase 488249 9796538 AARI_04510 Arthrobacter arilaitensis Re117 phospholipase/carboxylesterase YP_003915654.1 487599 D 861360 CDS YP_003915655.1 308176249 9796539 488299..488592 1 NC_014550.1 hypothetical protein 488592 9796539 AARI_04520 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915655.1 488299 D 861360 CDS YP_003915656.1 308176250 9796540 complement(488634..489740) 1 NC_014550.1 7 transmembrane helices predicted by TMHMM2.0; hypothetical protein 489740 9796540 AARI_04530 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915656.1 488634 R 861360 CDS YP_003915657.1 308176251 9796541 489813..490244 1 NC_014550.1 identified by match to protein family PF01047. Regulators with the marR-type HTH domain are present in bacteria and archaea and control a variety of biological functions, including resistance to multiple antibiotics, household disinfectants, organic solvents, oxidative stress agents and regulation of the virulence factor synthesis in pathogens of humans and plants. Many of the marR-like regulators respond to aromatic compounds; MarR family transcriptional regulator 490244 9796541 AARI_04540 Arthrobacter arilaitensis Re117 MarR family transcriptional regulator YP_003915657.1 489813 D 861360 CDS YP_003915658.1 308176252 9796542 complement(490269..490478) 1 NC_014550.1 hypothetical protein 490478 9796542 AARI_04550 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915658.1 490269 R 861360 CDS YP_003915659.1 308176253 9796543 complement(490517..491008) 1 NC_014550.1 involved in molybdoterin cofactor biosynthesis. Catalyses the following reaction: molybdopterin + ATP --> molybdopterin-AMP + diphosphate. The function of several enzymes, such as xanthine oxidase, sulfite oxidase, nitrate reductase, depends on the molybdopterin cofactor; molybdopterin adenylyltransferase 491008 mog 9796543 mog Arthrobacter arilaitensis Re117 molybdopterin adenylyltransferase YP_003915659.1 490517 R 861360 CDS YP_003915660.1 308176254 9794103 complement(490998..491474) 1 NC_014550.1 is involved, together with MoaA, in the conversion of a guanosine derivative (5 -GTP) into the molybdopterin precursor Z. The function of several enzymes, such as xanthine oxidase, sulfite oxidase, nitrate reductase, depends on the molybdopterin cofactor; molybdenum cofactor biosynthesis protein C 491474 moaC 9794103 moaC Arthrobacter arilaitensis Re117 molybdenum cofactor biosynthesis protein C YP_003915660.1 490998 R 861360 CDS YP_003915661.1 308176255 9794095 complement(491467..492699) 1 NC_014550.1 involved in the biosynthesis of a demolybdo- cofactor (molybdopterin), necessary for molybdo-enzymes such as xanthine oxidase, sulfite oxidase, nitrate reductase: molybdopterin-AMP + molybdate --> molybdenum cofactor + AMP + H2O; molybdopterin biosynthesis protein MoeA 492699 moeA 9794095 moeA Arthrobacter arilaitensis Re117 molybdopterin biosynthesis protein MoeA YP_003915661.1 491467 R 861360 CDS YP_003915662.1 308176256 9794101 complement(492703..492954) 1 NC_014550.1 molybdoterin synthase converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. Heterodimer of 2 MoaD subunits and 2 MoaE subunits; molybdopterin-converting factor small subunit MoaD 492954 moaD 9794101 moaD Arthrobacter arilaitensis Re117 molybdopterin-converting factor small subunit MoaD YP_003915662.1 492703 R 861360 CDS YP_003915663.1 308176257 9794096 492992..494173 1 NC_014550.1 involved in the biosynthesis of a demolybdo cofactor (molybdopterin), necessary for molybdoenzymes. Plays a role in the activation of the small subunit of the molybdopterin converting factor (MoaD); molybdopterin biosynthesis protein MoeB 494173 moeB 9794096 moeB Arthrobacter arilaitensis Re117 molybdopterin biosynthesis protein MoeB YP_003915663.1 492992 D 861360 CDS YP_003915664.1 308176258 9794102 494170..494577 1 NC_014550.1 molybdoterin synthase converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. Heterodimer of 2 MoaD subunits and 2 MoaE subunits; molybdopterin-converting factor large subunit MoaE 494577 moaE 9794102 moaE Arthrobacter arilaitensis Re117 molybdopterin-converting factor large subunit MoaE YP_003915664.1 494170 D 861360 CDS YP_003915665.1 308176259 9794097 494626..495042 1 NC_014550.1 hypothetical protein 495042 9794097 AARI_04620 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915665.1 494626 D 861360 CDS YP_003915666.1 308176260 9796544 complement(495175..496131) 1 NC_014550.1 transcriptional regulator 496131 9796544 AARI_04630 Arthrobacter arilaitensis Re117 transcriptional regulator YP_003915666.1 495175 R 861360 CDS YP_003915667.1 308176261 9796545 496236..496784 1 NC_014550.1 hypothetical protein 496784 9796545 AARI_04640 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915667.1 496236 D 861360 CDS YP_003915668.1 308176262 9796546 complement(496781..497821) 1 NC_014550.1 is involved, together with MoaC, in the conversion of a guanosine derivative (5 -GTP) into the molybdopterin precursor Z. The function of several enzymes, such as xanthine oxidase, sulfite oxidase, nitrate reductase, depends on the molybdopterin cofactor; molybdenum cofactor biosynthesis protein A 497821 moaA 9796546 moaA Arthrobacter arilaitensis Re117 molybdenum cofactor biosynthesis protein A YP_003915668.1 496781 R 861360 CDS YP_003915669.1 308176263 9794094 497954..498724 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, MolT- family (molybdate uptake transporter), molybdate porter (TC 3.A.1.8.1). ABCISSE: ABC transporter, binding protein (BP), MOI-family, molybdate import. Part of the ABC transporter complex ModABC involved in molybdate import; molybdate ABC transporter substrate-binding protein ModA 498724 modA 9794094 modA Arthrobacter arilaitensis Re117 molybdate ABC transporter substrate-binding protein ModA YP_003915669.1 497954 D 861360 CDS YP_003915670.1 308176264 9794099 498717..499523 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, MolT- family (molybdate uptake transporter), molybdate porter (TC 3.A.1.8.1). ABCISSE: ABC transporter, permease (IM), MOI-family, molybdate import. Part of the ABC transporter complex ModABC involved in molybdate import; molybdate ABC transporter inner membrane subunit ModB 499523 modB 9794099 modB Arthrobacter arilaitensis Re117 molybdate ABC transporter inner membrane subunit ModB YP_003915670.1 498717 D 861360 CDS YP_003915671.1 308176265 9794100 499520..501517 1 NC_014550.1 N-terminal section of the protein: ABC transporter, ATP-binding subunit ModC; TCDB: ATP-binding cassette (ABC) superfamily, MolT-family (molybdate uptake transporter), molybdate porter (TC 3.A.1.8.1). ABCISSE: ABC transporter, ATP-binding protein (ABC), MOI-family, molybdate import. Part of the ABC transporter complex ModABC involved in molybdate import. C-terminal section of the protein: molybdopterin biosynthesis protein MoeA; involved in the biosynthesis of a demolybdo-cofactor (molybdopterin), necessary for molybdo-enzymes such as xanthine oxidase, sulfite oxidase, nitrate reductase: molybdopterin-AMP + molybdate --> molybdenum cofactor + AMP + H2O; molybdate transport/synthesis fusion protein 501517 9794100 AARI_04680 Arthrobacter arilaitensis Re117 molybdate transport/synthesis fusion protein YP_003915671.1 499520 D 861360 CDS YP_003915672.1 308176266 9796547 501514..502392 1 NC_014550.1 links a guanosine 5 -phosphate to molydopterin, forming molybdopterin guanine dinucleotide: molybdenum cofactor + GTP = molybdopterin guanine dinucleotide + diphosphate + 2 H2O; molybdopterin-guanine dinucleotide biosynthesis protein A 502392 mobA 9796547 mobA Arthrobacter arilaitensis Re117 molybdopterin-guanine dinucleotide biosynthesis protein A YP_003915672.1 501514 D 861360 CDS YP_003915673.1 308176267 9794098 complement(502481..503380) 1 NC_014550.1 match to PF02683: Cytochrome C biogenesis protein transmembrane region; disulfide bond formation protein 503380 9794098 AARI_04700 Arthrobacter arilaitensis Re117 disulfide bond formation protein YP_003915673.1 502481 R 861360 CDS YP_003915674.1 308176268 9796548 complement(503380..504129) 1 NC_014550.1 match to protein domain PF01323; DSBA-like thioredoxin domain-containing protein 504129 9796548 AARI_04710 Arthrobacter arilaitensis Re117 DSBA-like thioredoxin domain-containing protein YP_003915674.1 503380 R 861360 CDS YP_003915675.1 308176269 9796549 complement(504458..505471) 1 NC_014550.1 permease 505471 9796549 AARI_04720 Arthrobacter arilaitensis Re117 permease YP_003915675.1 504458 R 861360 CDS YP_003915676.1 308176270 9796550 505636..506529 1 NC_014550.1 identified by match to PF00126: bacterial regulatory helix-turn-helix protein, lysR family. Numerous bacterial transcription regulatory proteins bind DNA via a helix-turn-helix (HTH) motif. These proteins are very diverse, but for convenience may be grouped into subfamilies on the basis of sequence similarity. One such family, the lysR family, groups together a range of proteins, including ampR, catM, catR, cynR, cysB, gltC, iciA, ilvY, irgB, lysR, metR, mkaC, mleR, nahR, nhaR, nodD, nolR, oxyR, pssR, rbcR, syrM, tcbR, tfdS and trpI. The majority of these proteins appear to be transcription activators and most are known to negatively regulate their own expression. All possess a potential HTH DNA-binding motif towards their N-termini; LysR family transcriptional regulator 506529 9796550 AARI_04730 Arthrobacter arilaitensis Re117 LysR family transcriptional regulator YP_003915676.1 505636 D 861360 CDS YP_003915677.1 308176271 9796551 complement(506703..507473) 1 NC_014550.1 the respiratory nitrate reductase enzyme complex allows the bacteria to use nitrate as an electron acceptor during anaerobic growth. The gamma subunit is a b-type cytochrome that receives electrons from the quinone pool. It then transfers these via the iron-sulfur clusters of the beta subunit to the molybdenum cofactor found in the alpha subunit; respiratory nitrate reductase gamma subunit 507473 narI 9796551 narI Arthrobacter arilaitensis Re117 respiratory nitrate reductase gamma subunit YP_003915677.1 506703 R 861360 CDS YP_003915678.1 308176272 9794134 complement(507470..508168) 1 NC_014550.1 the respiratory nitrate reductase enzyme complex allows the bacteria to use nitrate as an electron acceptor during anaerobic growth. The delta subunit is not part of the nitrate reductase enzyme but is most likely needed for assembly of the multi-subunit enzyme complex; respiratory nitrate reductase delta subunit 508168 narJ 9794134 narJ Arthrobacter arilaitensis Re117 respiratory nitrate reductase delta subunit YP_003915678.1 507470 R 861360 CDS YP_003915679.1 308176273 9794135 complement(508165..509802) 1 NC_014550.1 the respiratory nitrate reductase enzyme complex allows the bacteria to use nitrate as an electron acceptor during anaerobic growth; respiratory nitrate reductase beta subunit 509802 narH 9794135 narH Arthrobacter arilaitensis Re117 respiratory nitrate reductase beta subunit YP_003915679.1 508165 R 861360 CDS YP_003915680.1 308176274 9796553 513815..514966 1 NC_014550.1 major facilitator superfamily, nitrate/nitrite porter family, 24 TMS, 2 domain, NarK1-NarK2 porter (TC 2. A.1.8.11). In Paracoccus pantotrophus, this transporter comprises 2 domains: NarK1, a NO3-/H+ symporter; and NarK2, a NO3-/NO2- antiporter; nitrate/nitrite transporter 514966 9796553 AARI_04790 Arthrobacter arilaitensis Re117 nitrate/nitrite transporter YP_003915680.1 513815 D 861360 CDS YP_003915681.1 308176275 9796554 515046..515588 1 NC_014550.1 identified by match to protein family PF07152. This family consists of several hypothetical bacterial proteins of around 180 residues in length, which are often known as YaeQ. YaeQ is homologous to RfaH, a specialised transcription elongation protein. YaeQ is known to compensate for loss of RfaH function in Escherichia coli and Salmonella typhimurium; YaeQ family protein 515588 9796554 AARI_04800 Arthrobacter arilaitensis Re117 YaeQ family protein YP_003915681.1 515046 D 861360 CDS YP_003915682.1 308176276 9796555 515686..516762 1 NC_014550.1 glycerophosphoryl diester phosphodiesterases display broad specificity for glycerophosphodiesters; glycerophosphocholine, glycerophosphoethanolamine, glycerophosphoglycerol, and bis(glycerophosphoglycerol); glycerophosphodiester phosphodiesterase 516762 glpQ 9796555 glpQ Arthrobacter arilaitensis Re117 glycerophosphodiester phosphodiesterase YP_003915682.1 515686 D 861360 CDS YP_003915683.1 308176277 9793914 complement(517349..517741) 1 NC_014550.1 hypothetical protein 517741 9793914 AARI_04820 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915683.1 517349 R 861360 CDS YP_003915684.1 308176278 9793582 complement(518529..519005) 1 NC_014550.1 catalyzes the hydrolysis of cytosine into uracil and ammonia; cytosine deaminase 519005 codA 9793582 codA Arthrobacter arilaitensis Re117 cytosine deaminase YP_003915684.1 518529 R 861360 CDS YP_003915685.1 308176279 9793753 519175..519822 1 NC_014550.1 catalyses the formation of UMP and diphosphate from uracil and 5-phospho-alpha-D-ribose 1-diphosphate; uracil phosphoribosyltransferase 519822 upp 9793753 upp Arthrobacter arilaitensis Re117 uracil phosphoribosyltransferase YP_003915685.1 519175 D 861360 CDS YP_003915686.1 308176280 9794490 complement(519859..521370) 1 NC_014550.1 protein-histidine kinases are key elements in two- component signal transduction systems, which enable bacteria to sense, respond, and adapt to a wide range of environments, stressors, and growth conditions; signal transduction histidine kinase 521370 9794490 AARI_04850 Arthrobacter arilaitensis Re117 signal transduction histidine kinase YP_003915686.1 519859 R 861360 CDS YP_003915687.1 308176281 9796557 complement(521367..522107) 1 NC_014550.1 response regulators are key elements in two- component signal transduction systems, which enable bacteria to sense, respond, and adapt to a wide range of environments, stressors, and growth conditions; two-component system response regulator 522107 9796557 AARI_04860 Arthrobacter arilaitensis Re117 two-component system response regulator YP_003915687.1 521367 R 861360 CDS YP_003915688.1 308176282 9796558 522722..523507 1 NC_014550.1 response regulators are key elements in two- component signal transduction systems, which enable bacteria to sense, respond, and adapt to a wide range of environments, stressors, and growth conditions; two-component system response regulator 523507 9796558 AARI_04870 Arthrobacter arilaitensis Re117 two-component system response regulator YP_003915688.1 522722 D 861360 CDS YP_003915689.1 308176283 9796559 523577..524104 1 NC_014550.1 COG2062; phosphohistidine phosphatase SixA from Escherichia coli exhibits phosphatase activity towards the HPT domain of the ArcB sensor involved in the multistep his-asp phosphorelay; regulatory protein 524104 9796559 AARI_04880 Arthrobacter arilaitensis Re117 regulatory protein YP_003915689.1 523577 D 861360 CDS YP_003915690.1 308176284 9796560 524331..525458 1 NC_014550.1 hypothetical protein 525458 9796560 AARI_04890 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915690.1 524331 D 861360 CDS YP_003915691.1 308176285 9796561 525467..527080 1 NC_014550.1 TC 3.A.1.117.z. ABCISSE: ABC transporter, permease and ATP-binding protein (IM-ABC), DPL-family, antibiotic resistance or production (ARP) subfamily. Possible function in antibiotic resistance or production (export); drug resistance ATP-binding protein 527080 9796561 AARI_04900 Arthrobacter arilaitensis Re117 drug resistance ATP-binding protein YP_003915691.1 525467 D 861360 CDS YP_003915692.1 308176286 9796562 complement(527077..527688) 1 NC_014550.1 match to PF00440: bacterial regulatory proteins, tetR family; transcriptional regulator 527688 9796562 AARI_04910 Arthrobacter arilaitensis Re117 transcriptional regulator YP_003915692.1 527077 R 861360 CDS YP_003915693.1 308176287 9796563 complement(527685..530015) 1 NC_014550.1 TC 9.B.74.y.z. The phage infection protein (PIP) family is a transport protein family. Identified by match to protein domains TIGR03061 and TIGR03062; PIP family transporter 530015 9796563 AARI_04920 Arthrobacter arilaitensis Re117 PIP family transporter YP_003915693.1 527685 R 861360 CDS YP_003915694.1 308176288 9796564 complement(530019..530801) 1 NC_014550.1 hypothetical protein 530801 9796564 AARI_04930 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915694.1 530019 R 861360 CDS YP_003915695.1 308176289 9796565 531023..532939 1 NC_014550.1 match to PF03372: Endonuclease/Exonuclease/phosphatase family. This large family of proteins includes magnesium dependent endonucleases and a large number of phosphatases involved in intracellular signalling. Signal peptide predicted by SignalP 3.0 HMM (probability: 1.000) with cleavage site probability 0.974 between position 28 and 29; extracellular nuclease 532939 9796565 AARI_04940 Arthrobacter arilaitensis Re117 extracellular nuclease YP_003915695.1 531023 D 861360 CDS YP_003915696.1 308176290 9796568 534691..535854 1 NC_014550.1 identified by similarity to protein SP: Q9LAV7 (Thermobifida fusca). TCDB: ATP-binding cassette (ABC) superfamily, carbohydrate uptake transporter-1 (CUT1) family (TC 3.A.1.1.z). ABCISSE: ABC transporter, permease (IM), OSP-family (oligosaccharides or polyols), cellobiose import; cellobiose ABC transporter inner membrane subunit BglA 535854 bglA 9796568 bglA Arthrobacter arilaitensis Re117 cellobiose ABC transporter inner membrane subunit BglA YP_003915696.1 534691 D 861360 CDS YP_003915697.1 308176291 9793713 535862..536734 1 NC_014550.1 identified by similarity to protein SP: Q9LAV6 (Thermobifida fusca). TCDB: ATP-binding cassette (ABC) superfamily, carbohydrate uptake transporter-1 (CUT1) family (TC 3.A.1.1.z). ABCISSE: ABC transporter, binding protein (BP), OSP-family (oligosaccharides or polyols), cellobiose import; cellobiose ABC transporter substrate-binding protein BglB 536734 bglB 9793713 bglB Arthrobacter arilaitensis Re117 cellobiose ABC transporter substrate-binding protein BglB YP_003915697.1 535862 D 861360 CDS YP_003915698.1 308176292 9793714 536734..538152 1 NC_014550.1 identified by similarity to protein SP:Q9LAV5 (Thermobifida fusca). In Thermobifida fusca, bglC is most active against cellobiose; beta-glucosidase BglC 538152 bglC 9793714 bglC Arthrobacter arilaitensis Re117 beta-glucosidase BglC YP_003915698.1 536734 D 861360 CDS YP_003915699.1 308176293 9793715 538247..539266 1 NC_014550.1 identified by similarity to protein SP:O87590 (Thermobifida fusca). In Thermobifida fusca, CelR Binds to the 14-bp operator sequence 5-TGGGAGCGCTCCCA-3 in the upstream regions of cellulase genes; these operator sequences are modulated by cellobiose; LacI family transcriptional regulator CelR 539266 celR 9793715 celR Arthrobacter arilaitensis Re117 LacI family transcriptional regulator CelR YP_003915699.1 538247 D 861360 CDS YP_003915700.1 308176294 9796569 complement(539984..540097) 1 NC_014550.1 hypothetical protein 540097 9796569 AARI_05020 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915700.1 539984 R 861360 CDS YP_003915701.1 308176295 9793584 540550..542382 1 NC_014550.1 catalyzes the formation of phosphoenolpyruvate by decarboxylation of oxaloacetate while hydrolyzing GTP; phosphoenolpyruvate carboxykinase (GTP) 542382 pckG 9793584 pckG Arthrobacter arilaitensis Re117 phosphoenolpyruvate carboxykinase (GTP) YP_003915701.1 540550 D 861360 CDS YP_003915702.1 308176296 9794187 542551..543078 1 NC_014550.1 identified by match to protein family PF03551; PadR-like family transcriptional regulator 543078 9794187 AARI_05040 Arthrobacter arilaitensis Re117 PadR-like family transcriptional regulator YP_003915702.1 542551 D 861360 CDS YP_003915703.1 308176297 9796571 543075..544157 1 NC_014550.1 match to PF00561: alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes; hydrolase 544157 9796571 AARI_05050 Arthrobacter arilaitensis Re117 hydrolase YP_003915703.1 543075 D 861360 CDS YP_003915704.1 308176298 9796572 complement(544225..545400) 1 NC_014550.1 flavohemoproteins from bacteria (e.g. Escherichia coli hmpA) and fungi consist of two distinct domains, an N- terminal globin domain and a C-terminal FAD-containing reductase domain; flavohemoprotein 545400 9796572 AARI_05060 Arthrobacter arilaitensis Re117 flavohemoprotein YP_003915704.1 544225 R 861360 CDS YP_003915705.1 308176299 9796573 complement(545546..546004) 1 NC_014550.1 identified by match to protein family PF02082; transcriptional regulator 546004 9796573 AARI_05070 Arthrobacter arilaitensis Re117 transcriptional regulator YP_003915705.1 545546 R 861360 CDS YP_003915706.1 308176300 9796574 complement(546082..546552) 1 NC_014550.1 hypothetical protein 546552 9796574 AARI_05080 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915706.1 546082 R 861360 CDS YP_003915707.1 308176301 9796575 complement(546565..547989) 1 NC_014550.1 catalyses the following reaction: alpha-D-mannose 1- phosphate <=> D-mannose 6-phosphate; phosphomannomutase 547989 manB 9796575 manB Arthrobacter arilaitensis Re117 phosphomannomutase YP_003915707.1 546565 R 861360 CDS YP_003915708.1 308176302 9794056 548166..550286 1 NC_014550.1 match to protein family TIGR00614: recQ family; ATP-dependent DNA helicase 550286 9794056 AARI_05100 Arthrobacter arilaitensis Re117 ATP-dependent DNA helicase YP_003915708.1 548166 D 861360 CDS YP_003915709.1 308176303 9796576 550317..551225 1 NC_014550.1 1 transmembrane helice predicted by TMHMM2.0; hypothetical protein 551225 9796576 AARI_05110 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915709.1 550317 D 861360 CDS YP_003915710.1 308176304 9793585 complement(551768..553855) 1 NC_014550.1 identified by match to PF00326 and PF02897. Prolyl oligopeptidase family consist of a number of evolutionary related peptidases whose catalytic activity seems to be provided by a charge relay system similar to that of the trypsin family of serine proteases, but which evolved by independent convergent evolution; prolyl oligopeptidase 553855 9793585 AARI_05120 Arthrobacter arilaitensis Re117 prolyl oligopeptidase YP_003915710.1 551768 R 861360 CDS YP_003915711.1 308176305 9796578 553912..555927 1 NC_014550.1 hypothetical protein 555927 9796578 AARI_05130 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915711.1 553912 D 861360 CDS YP_003915712.1 308176306 9793586 556113..557102 1 NC_014550.1 NADPH:quinone reductase catalyzes the following reaction: NADPH + quinone <=> NADP(+) + semiquinone. Quinone or similar compounds may act as acceptor; NADPH:quinone reductase 557102 qor 9793586 qor Arthrobacter arilaitensis Re117 NADPH:quinone reductase YP_003915712.1 556113 D 861360 CDS YP_003915713.1 308176307 9797151 558231..558422 1 NC_014550.1 hypothetical protein 558422 9797151 AARI_05150 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915713.1 558231 D 861360 CDS YP_003915714.1 308176308 9796580 558576..559025 1 NC_014550.1 hypothetical protein 559025 9796580 AARI_05160 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915714.1 558576 D 861360 CDS YP_003915715.1 308176309 9797154 560320..561162 1 NC_014550.1 catalyzes the reduction of 2,5-diketogluconic acid to 2-keto-L-gulonic acid, a key intermediate in the production of ascorbic acid. Can also reduce ethyl 2- methylacetoacetate stereoselectively to ethyl (2R)-methyl- (3S)-hydroxybutanoate and can also accept some other beta- keto esters. Identified by similarity to protein SP:Q46857 (Escherichia coli); 2,5-didehydrogluconate reductase 561162 dkgA 9797154 dkgA Arthrobacter arilaitensis Re117 2,5-didehydrogluconate reductase YP_003915715.1 560320 D 861360 CDS YP_003915716.1 308176310 9793587 complement(561520..563037) 1 NC_014550.1 match to protein family PF08386. This is a C- terminal domain associated with hydrolases and bacterial peptidases that belong to MEROPS peptidase family S33 (clan SC). Signal peptide predicted by SignalP 3.0 HMM (probability: 1.000) with cleavage site probability 0.604 between position 25 and 26; peptidase S33 563037 9793587 AARI_05180 Arthrobacter arilaitensis Re117 peptidase S33 YP_003915716.1 561520 R 861360 CDS YP_003915717.1 308176311 9796582 complement(563079..564233) 1 NC_014550.1 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The beta chain is required for initiation of replication once it is clamped onto DNA. DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII complex. PolIII associates with the gamma complex (composed of gamma, delta, delta prime, psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex; DNA polymerase III subunit delta prime 564233 9796582 AARI_05190 Arthrobacter arilaitensis Re117 DNA polymerase III subunit delta prime YP_003915717.1 563079 R 861360 CDS YP_003915718.1 308176312 9796583 complement(564230..564883) 1 NC_014550.1 catalyzes the phosphorylation of thymidine 5- monophosphate (dTMP) to thymidine 5-diphosphate (dTDP) in the presence of ATP and magnesium; dTMP kinase 564883 tmk 9796583 tmk Arthrobacter arilaitensis Re117 dTMP kinase YP_003915718.1 564230 R 861360 CDS YP_003915719.1 308176313 9797156 566256..567413 1 NC_014550.1 catalyzes the conversion of cysteine and succinyl- homoserine into cystathionine and succinate. Several other reactions may also be catalysed in some organisms; cystathionine gamma-synthase 567413 metB 9797156 metB Arthrobacter arilaitensis Re117 cystathionine gamma-synthase YP_003915719.1 566256 D 861360 CDS YP_003915720.1 308176314 9794067 567485..567802 1 NC_014550.1 3 transmembrane helices predicted by TMHMM2.0; hypothetical protein 567802 9794067 AARI_05220 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915720.1 567485 D 861360 CDS YP_003915721.1 308176315 9796584 567935..568681 1 NC_014550.1 catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase 568681 gpmA 9796584 gpmA Arthrobacter arilaitensis Re117 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase YP_003915721.1 567935 D 861360 CDS YP_003915722.1 308176316 9793933 568880..569182 1 NC_014550.1 hypothetical protein 569182 9793933 AARI_05240 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915722.1 568880 D 861360 CDS YP_003915723.1 308176317 9796585 complement(569427..570080) 1 NC_014550.1 probably involved in phosphate transport and/or metabolism. Identified by match to PF01895; phosphate transport system regulatory protein PhoU 570080 phoU 9796585 phoU Arthrobacter arilaitensis Re117 phosphate transport system regulatory protein PhoU YP_003915723.1 569427 R 861360 CDS YP_003915724.1 308176318 9794206 570317..571522 1 NC_014550.1 protein-histidine kinases are key elements in two- component signal transduction systems, which enable bacteria to sense, respond, and adapt to a wide range of environments, stressors, and growth conditions; signal transduction histidine kinase 571522 9794206 AARI_05260 Arthrobacter arilaitensis Re117 signal transduction histidine kinase YP_003915724.1 570317 D 861360 CDS YP_003915725.1 308176319 9796586 571519..572199 1 NC_014550.1 response regulators are key elements in two- component signal transduction systems, which enable bacteria to sense, respond, and adapt to a wide range of environments, stressors, and growth conditions; two-component system response regulator 572199 9796586 AARI_05270 Arthrobacter arilaitensis Re117 two-component system response regulator YP_003915725.1 571519 D 861360 CDS YP_003915726.1 308176320 9796587 complement(572284..572823) 1 NC_014550.1 signal peptide predicted by SignalP 3.0 HMM (probability: 0.991) with cleavage site probability 0.479 between position 35 and 36; hypothetical protein 572823 9796587 AARI_05280 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915726.1 572284 R 861360 CDS YP_003915727.1 308176321 9796588 573179..573664 1 NC_014550.1 CarD is a Myxococcus xanthus protein required for the activation of light- and starvation-inducible genes; CarD transcriptional regulator-like protein 573664 9796588 AARI_05290 Arthrobacter arilaitensis Re117 CarD transcriptional regulator-like protein YP_003915727.1 573179 D 861360 CDS YP_003915728.1 308176322 9796589 573769..575010 1 NC_014550.1 bifunctional enzyme catalyzing non-consecutive reactions in the 1-deoxy-D-xylulose 5-phosphate pathway of isoprenoid precursor biosynthesis; bifunctional 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase/2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase protein 575010 ispDF 9796589 ispDF Arthrobacter arilaitensis Re117 bifunctional 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase/2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase protein YP_003915728.1 573769 D 861360 CDS YP_003915729.1 308176323 9794011 575098..576549 1 NC_014550.1 activates cysteine and transfers it to tRNA(Cys) as the first step in protein biosynthesis; cysteine--tRNA ligase 576549 cysS 9794011 cysS Arthrobacter arilaitensis Re117 cysteine--tRNA ligase YP_003915729.1 575098 D 861360 CDS YP_003915730.1 308176324 9793784 576600..577547 1 NC_014550.1 identified by match to protein family PF00588: SpoU rRNA Methylase family. Possible role in rRNA modification; RNA methyltransferase 577547 9793784 AARI_05320 Arthrobacter arilaitensis Re117 RNA methyltransferase YP_003915730.1 576600 D 861360 CDS YP_003915731.1 308176325 9793590 583851..584060 1 NC_014550.1 hypothetical protein 584060 9793590 AARI_05330 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915731.1 583851 D 861360 CDS YP_003915732.1 308176326 9796591 584530..585906 1 NC_014550.1 identified by match to PF02913 and PF01565; FAD linked oxidase domain-containing protein 585906 9796591 AARI_05340 Arthrobacter arilaitensis Re117 FAD linked oxidase domain-containing protein YP_003915732.1 584530 D 861360 CDS YP_003915733.1 308176327 9793591 586292..586927 1 NC_014550.1 hypothetical protein 586927 9793591 AARI_05350 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915733.1 586292 D 861360 CDS YP_003915734.1 308176328 9796593 complement(587613..588047) 1 NC_014550.1 hypothetical protein 588047 9796593 AARI_05360 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915734.1 587613 R 861360 CDS YP_003915735.1 308176329 9793593 complement(588703..589902) 1 NC_014550.1 transposase of ISAar5, IS256 family 589902 9793593 AARI_34550 Arthrobacter arilaitensis Re117 transposase of ISAar5, IS256 family YP_003915735.1 588703 R 861360 CDS YP_003915736.1 308176330 9793596 597118..597414 1 NC_014550.1 3 transmembrane helices predicted by TMHMM2.0; hypothetical protein 597414 9793596 AARI_05370 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915736.1 597118 D 861360 CDS YP_003915737.1 308176331 9796595 597710..598492 1 NC_014550.1 dehydrogenase 598492 9796595 AARI_05380 Arthrobacter arilaitensis Re117 dehydrogenase YP_003915737.1 597710 D 861360 CDS YP_003915738.1 308176332 9796677 complement(598883..599950) 1 NC_014550.1 identified by similarity to protein SP:P96483 (Streptomyces reticuli). In Streptomyces reticuli, MsiK assists the cellobiose and maltose ABC transport systems. TCDB: ATP-binding cassette (ABC) superfamily, carbohydrate uptake transporter-1 (CUT1) family (TC 3.A.1.1.z). ABCISSE: ABC transporter, ATP-binding protein (ABC), OSP- family (oligosaccharides or polyols); cellobiose/maltose ABC transporter ATP-binding subunit MsiK 599950 msiK 9796677 msiK Arthrobacter arilaitensis Re117 cellobiose/maltose ABC transporter ATP-binding subunit MsiK YP_003915738.1 598883 R 861360 CDS YP_003915739.1 308176333 9794109 complement(600016..600795) 1 NC_014550.1 synthesis of trehalose from trehalose-6-phosphate; trehalose-phosphatase 600795 otsB 9794109 otsB Arthrobacter arilaitensis Re117 trehalose-phosphatase YP_003915739.1 600016 R 861360 CDS YP_003915740.1 308176334 9794162 complement(600838..602301) 1 NC_014550.1 synthesis of trehalose 6-phosphate from UDP-glucose and glucose-6-phosphate; alpha,alpha-trehalose-phosphate synthase 602301 otsA 9794162 otsA Arthrobacter arilaitensis Re117 alpha,alpha-trehalose-phosphate synthase YP_003915740.1 600838 R 861360 CDS YP_003915741.1 308176335 9794161 602701..603567 1 NC_014550.1 match to protein domain PF01323; DSBA-like thioredoxin domain-containing protein 603567 9794161 AARI_05420 Arthrobacter arilaitensis Re117 DSBA-like thioredoxin domain-containing protein YP_003915741.1 602701 D 861360 CDS YP_003915742.1 308176336 9793597 603981..604931 1 NC_014550.1 4 transmembrane helices predicted by TMHMM2.0; hypothetical protein 604931 9793597 AARI_05430 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915742.1 603981 D 861360 CDS YP_003915743.1 308176337 9796679 605042..606691 1 NC_014550.1 match to PF02384. This domain is found in N-6 adenine-specific DNA methylase from type I and type IC restriction systems. These enzymes are responsible for the methylation of specific DNA sequences in order to prevent the host from digesting its own genome via its restriction enzymes. Match to PS00092 pattern: N-6 Adenine-specific DNA methylases signature; adenine-specific DNA-methyltransferase 606691 9796679 AARI_05440 Arthrobacter arilaitensis Re117 adenine-specific DNA-methyltransferase YP_003915743.1 605042 D 861360 CDS YP_003915744.1 308176338 9796680 606688..607620 1 NC_014550.1 hypothetical protein 607620 9796680 AARI_05450 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915744.1 606688 D 861360 CDS YP_003915745.1 308176339 9796681 complement(607625..608242) 1 NC_014550.1 identified by match to PF00583: acetyltransferase (GNAT) family; GNAT family acetyltransferase 608242 9796681 AARI_05460 Arthrobacter arilaitensis Re117 GNAT family acetyltransferase YP_003915745.1 607625 R 861360 CDS YP_003915746.1 308176340 9793598 complement(608787..609833) 1 NC_014550.1 identified by match to PF00296. Bacterial luciferase is a flavin monooxygenase that catalyses the oxidation of long-chain aldehydes and releases energy in the form of visible light, and which uses flavin as a substrate rather than a cofactor. There are structural similarities between bacterial luciferase and nonfluorescent flavoproteins (LuxF, FP390), alkanesulfonate monooxygenase (SsuD), and coenzyme F420- dependent terahydromethanopterin reductase, which make up clearly related families with somewhat different folds; luciferase-like monooxygenase 609833 9793598 AARI_05470 Arthrobacter arilaitensis Re117 luciferase-like monooxygenase YP_003915746.1 608787 R 861360 CDS YP_003915747.1 308176341 9796683 610034..611704 1 NC_014550.1 9 transmembrane helices predicted by TMHMM2.0; hypothetical protein 611704 9796683 AARI_05480 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915747.1 610034 D 861360 CDS YP_003915748.1 308176342 9796684 complement(611701..612375) 1 NC_014550.1 DNA repair enzyme that excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; uracil-DNA glycosylase 612375 ung 9796684 ung Arthrobacter arilaitensis Re117 uracil-DNA glycosylase YP_003915748.1 611701 R 861360 CDS YP_003915749.1 308176343 9794489 612631..612921 1 NC_014550.1 hypothetical protein 612921 9794489 AARI_05500 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915749.1 612631 D 861360 CDS YP_003915750.1 308176344 9796685 612964..613569 1 NC_014550.1 1 transmembrane helice predicted by TMHMM2.0; hypothetical protein 613569 9796685 AARI_05510 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915750.1 612964 D 861360 CDS YP_003915751.1 308176345 9796686 613868..615505 1 NC_014550.1 chaperonins are involved in productive folding of proteins. With the aid of cochaperonin GroES, GroEL encapsulates non-native substrate proteins inside the cavity of the GroEL-ES complex and promotes folding by using energy derived from ATP hydrolysis; chaperonin GroEL 615505 groEL 9796686 groEL Arthrobacter arilaitensis Re117 chaperonin GroEL YP_003915751.1 613868 D 861360 CDS YP_003915752.1 308176346 9793936 complement(615609..616499) 1 NC_014550.1 hypothetical protein 616499 9793936 AARI_05530 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915752.1 615609 R 861360 CDS YP_003915753.1 308176347 9796687 complement(616543..616833) 1 NC_014550.1 hypothetical protein 616833 9796687 AARI_05540 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915753.1 616543 R 861360 CDS YP_003915754.1 308176348 9796688 complement(616947..618485) 1 NC_014550.1 protein-histidine kinases are key elements in two- component signal transduction systems, which enable bacteria to sense, respond, and adapt to a wide range of environments, stressors, and growth conditions; signal transduction histidine kinase 618485 9796688 AARI_05550 Arthrobacter arilaitensis Re117 signal transduction histidine kinase YP_003915754.1 616947 R 861360 CDS YP_003915755.1 308176349 9796689 complement(618538..619245) 1 NC_014550.1 response regulators are key elements in two- component signal transduction systems, which enable bacteria to sense, respond, and adapt to a wide range of environments, stressors, and growth conditions; two-component system response regulator 619245 9796689 AARI_05560 Arthrobacter arilaitensis Re117 two-component system response regulator YP_003915755.1 618538 R 861360 CDS YP_003915756.1 308176350 9796690 complement(619304..619522) 1 NC_014550.1 hypothetical protein 619522 9796690 AARI_05570 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915756.1 619304 R 861360 CDS YP_003915757.1 308176351 9796691 619775..620158 1 NC_014550.1 N-terminal section of the protein: match to PF00313 (cold-shock DNA-binding domain). The so-called cold shock proteins are thought to help the cell to survive in temperatures lower than optimum growth temperature, by contrast with heat shock proteins, which help the cell to survive in temperatures greater than the optimum, possibly by condensation of the chromosome and organization of the prokaryotic nucleoid; cold shock protein 620158 9796691 AARI_05580 Arthrobacter arilaitensis Re117 cold shock protein YP_003915757.1 619775 D 861360 CDS YP_003915758.1 308176352 9796692 620162..620773 1 NC_014550.1 hypothetical protein 620773 9796692 AARI_05590 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915758.1 620162 D 861360 CDS YP_003915759.1 308176353 9796693 complement(620850..621971) 1 NC_014550.1 catalyzes the reversible interconversion of 3- phosphonooxypyruvate and glutamate to phosphoserine and 2- oxoglutarate to. It is required both in the major phosphorylated pathway of serine biosynthesis and in pyridoxine biosynthesis. Also catalyses the third step in the biosynthesis of the coenzyme pyridoxal 5-phosphate : (3R)-3-hydroxy-2-oxo-4-phosphonooxybutanoate + L-glutamate <=> 4-phosphonooxy-L-threonine + 2-oxoglutarate; phosphoserine transaminase 621971 serC 9796693 serC Arthrobacter arilaitensis Re117 phosphoserine transaminase YP_003915759.1 620850 R 861360 CDS YP_003915760.1 308176354 9794394 622233..622928 1 NC_014550.1 identified by similarity to protein SP:P0A672 (Mycobacterium tuberculosis). Iron-binding repressor of siderophore biosynthesis and iron uptake. Synonym: DtxR (Corynebacterium glutamicum); iron-dependent repressor IdeR 622928 ideR 9794394 ideR Arthrobacter arilaitensis Re117 iron-dependent repressor IdeR YP_003915760.1 622233 D 861360 CDS YP_003915761.1 308176355 9793997 623191..624237 1 NC_014550.1 identified by match to protein family PF01551. Members of this family are zinc metallopeptidases with a range of specificities. Peptidase family M23 are also endopeptidases; M23 family peptidase 624237 9793997 AARI_05620 Arthrobacter arilaitensis Re117 M23 family peptidase YP_003915761.1 623191 D 861360 CDS YP_003915762.1 308176356 9796694 624535..625362 1 NC_014550.1 hypothetical protein 625362 9796694 AARI_05630 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915762.1 624535 D 861360 CDS YP_003915763.1 308176357 9796695 625966..626088 1 NC_014550.1 hypothetical protein 626088 9796695 AARI_05640 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915763.1 625966 D 861360 CDS YP_003915764.1 308176358 9796696 complement(626126..626536) 1 NC_014550.1 hypothetical protein 626536 9796696 AARI_05650 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915764.1 626126 R 861360 CDS YP_003915765.1 308176359 9796697 626725..627954 1 NC_014550.1 identified by match to PF00480: ROK family; transcriptional regulator 627954 9796697 AARI_05660 Arthrobacter arilaitensis Re117 transcriptional regulator YP_003915765.1 626725 D 861360 CDS YP_003915766.1 308176360 9793599 complement(628217..628879) 1 NC_014550.1 4 transmembrane helices predicted by TMHMM2.0; hypothetical protein 628879 9793599 AARI_05670 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915766.1 628217 R 861360 CDS YP_003915767.1 308176361 9796699 628964..631342 1 NC_014550.1 an ATP-dependent DNA helicase which facilitates the progress of replication forks. Non-essential in Escherchichia coli, PcrA is an essential DNA helicase in Bacillus subtilis, fulfilling functions both in repair and rolling-circle replication; ATP-dependent DNA helicase PcrA 631342 pcrA 9796699 pcrA Arthrobacter arilaitensis Re117 ATP-dependent DNA helicase PcrA YP_003915767.1 628964 D 861360 CDS YP_003915768.1 308176362 9794189 631585..632757 1 NC_014550.1 succinyl-CoA synthetase, which is composed of alpha and beta subunits, catalyzes the interconversion of succinyl-CoA and succinate. Involved in the TCA cycle; succinyl-CoA synthetase beta subunit 632757 sucC 9794189 sucC Arthrobacter arilaitensis Re117 succinyl-CoA synthetase beta subunit YP_003915768.1 631585 D 861360 CDS YP_003915769.1 308176363 9794411 632774..633676 1 NC_014550.1 succinyl-CoA synthetase, which is composed of alpha and beta subunits, catalyzes the interconversion of succinyl-CoA and succinate. Involved in the TCA cycle; succinyl-CoA synthetase subunit alpha 633676 sucD 9794411 sucD Arthrobacter arilaitensis Re117 succinyl-CoA synthetase subunit alpha YP_003915769.1 632774 D 861360 CDS YP_003915770.1 308176364 9794412 633957..634460 1 NC_014550.1 hypothetical protein 634460 9794412 AARI_05710 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915770.1 633957 D 861360 CDS YP_003915771.1 308176365 9796700 complement(634550..636082) 1 NC_014550.1 identified by similarity to protein SP:P0C0L7 (Escherichia coli). Proton symporter that senses osmotic shifts and responds by importing osmolytes such as proline, glycine betaine, stachydrine, pipecolic acid, ectoine and taurine. It is both an osmosensor and an osmoregulator which is available to participate early in the bacterial osmoregulatory response. Metabolite:H+ symporter (MHS) family, (Poline/glycine-betaine):(H+/Na+) symporter (also transports taurine, ectoine, pipecolate, proline-betaine, N,N-dimethylglycine, carnitine, and 1- carboxymethyl-pyridinium) (subject to osmotic activation) (TC 2.A.1.6.4); proline/betaine transporter 636082 proP 9796700 proP Arthrobacter arilaitensis Re117 proline/betaine transporter YP_003915771.1 634550 R 861360 CDS YP_003915772.1 308176366 9794226 complement(636661..636945) 1 NC_014550.1 hypothetical protein 636945 9794226 AARI_05730 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915772.1 636661 R 861360 CDS YP_003915773.1 308176367 9796701 complement(637108..640455) 1 NC_014550.1 possible DNA or RNA helicase; ATP-dependent helicase 640455 9796701 AARI_05740 Arthrobacter arilaitensis Re117 ATP-dependent helicase YP_003915773.1 637108 R 861360 CDS YP_003915774.1 308176368 9796702 640542..641732 1 NC_014550.1 hypothetical protein 641732 9796702 AARI_05750 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915774.1 640542 D 861360 CDS YP_003915775.1 308176369 9796703 complement(641795..642898) 1 NC_014550.1 5 transmembrane helices predicted by TMHMM2.0; hypothetical protein 642898 9796703 AARI_05760 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915775.1 641795 R 861360 CDS YP_003915776.1 308176370 9796704 complement(642954..643220) 1 NC_014550.1 hypothetical protein 643220 9796704 AARI_05770 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915776.1 642954 R 861360 CDS YP_003915777.1 308176371 9796705 643296..643478 1 NC_014550.1 hypothetical protein 643478 9796705 AARI_05780 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915777.1 643296 D 861360 CDS YP_003915778.1 308176372 9796706 643633..644196 1 NC_014550.1 match to protein domain PF01381: helix-turn-helix; transcriptional regulator 644196 9796706 AARI_05790 Arthrobacter arilaitensis Re117 transcriptional regulator YP_003915778.1 643633 D 861360 CDS YP_003915779.1 308176373 9796707 644334..644750 1 NC_014550.1 3 transmembrane helices predicted by TMHMM2.0; hypothetical protein 644750 9796707 AARI_05800 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915779.1 644334 D 861360 CDS YP_003915780.1 308176374 9796708 645052..646038 1 NC_014550.1 catalyses the following reaction: 4- guanidinobutanoate + H(2)O <=> 4-aminobutanoate + urea. The ortholog found in Arthrobacter sp. KUJ 8602 also acts on D-arginine, 3-guanidinopropionate and L-arginine; guanidinobutyrase 646038 gbh 9796708 gbh Arthrobacter arilaitensis Re117 guanidinobutyrase YP_003915780.1 645052 D 861360 CDS YP_003915781.1 308176375 9793889 646038..647681 1 NC_014550.1 domain present in thiamine pyrophosphate-requiring enzymes (acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase); thiamine pyrophosphate binding domain-containing protein 647681 9793889 AARI_05820 Arthrobacter arilaitensis Re117 thiamine pyrophosphate binding domain-containing protein YP_003915781.1 646038 D 861360 CDS YP_003915782.1 308176376 9796709 complement(647775..647927) 1 NC_014550.1 hypothetical protein 647927 9796709 AARI_05830 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915782.1 647775 R 861360 CDS YP_003915783.1 308176377 9796710 complement(648064..648924) 1 NC_014550.1 catalyzes the following reaction: myo-inositol phosphate + H(2)O <=> myo-inositol + phosphate. Acts on five of the six isomers of myo-inositol phosphate, all except myo-inositol 2-phosphate, but does not act on myo- inositol bearing more than one phosphate group; inositol-phosphate phosphatase 648924 suhB 9796710 suhB Arthrobacter arilaitensis Re117 inositol-phosphate phosphatase YP_003915783.1 648064 R 861360 CDS YP_003915784.1 308176378 9794419 649027..649539 1 NC_014550.1 identified by match to protein family PF01047. Regulators with the marR-type HTH domain are present in bacteria and archaea and control a variety of biological functions, including resistance to multiple antibiotics, household disinfectants, organic solvents, oxidative stress agents and regulation of the virulence factor synthesis in pathogens of humans and plants. Many of the marR-like regulators respond to aromatic compounds; MarR family transcriptional regulator 649539 9794419 AARI_05850 Arthrobacter arilaitensis Re117 MarR family transcriptional regulator YP_003915784.1 649027 D 861360 CDS YP_003915785.1 308176379 9796711 649526..651085 1 NC_014550.1 major facilitator superfamily, drug:H+ antiporter-2 (14 spanner) (DHA2) family (TC 2.A.1.3.z); EmrB/QacA subfamily drug resistance transporter 651085 9796711 AARI_05860 Arthrobacter arilaitensis Re117 EmrB/QacA subfamily drug resistance transporter YP_003915785.1 649526 D 861360 CDS YP_003915786.1 308176380 9796712 651131..651850 1 NC_014550.1 identified by match to protein family PF00392. This family of regulatory proteins consists of the N-terminal HTH region of GntR-like bacterial transcription factors. At the C-terminus there is usually an effector- binding/oligomerisation domain. The GntR-like proteins can be divided into six sub-families: MocR, YtrR, FadR, AraR, HutC and PlmA. Many of these proteins have been shown experimentally to be autoregulatory, enabling the prediction of operator sites and the discovery of cis/trans relationships; GntR family transcriptional regulator 651850 9796712 AARI_05870 Arthrobacter arilaitensis Re117 GntR family transcriptional regulator YP_003915786.1 651131 D 861360 CDS YP_003915787.1 308176381 9796713 651994..653139 1 NC_014550.1 CoA-transferases catalyse reversible transfer reactions of coenzyme A groups from CoA-thioesters to free acids; CoA-transferase 653139 9796713 AARI_05880 Arthrobacter arilaitensis Re117 CoA-transferase YP_003915787.1 651994 D 861360 CDS YP_003915788.1 308176382 9796714 653167..654345 1 NC_014550.1 possibly involved in the metabolism of lipids. Match to protein domains PF08028, PF02771 and PF02770. Acyl-CoA dehydrogenases catalyze the alpha,beta- dehydrogenation of acyl-CoA thioesters to the corresponding trans 2,3-enoyl CoA-products with concommitant reduction of enzyme-bound FAD; acyl-CoA dehydrogenase 654345 9796714 AARI_05890 Arthrobacter arilaitensis Re117 acyl-CoA dehydrogenase YP_003915788.1 653167 D 861360 CDS YP_003915789.1 308176383 9796715 654377..655834 1 NC_014550.1 catalyses the following reaction: an aldehyde + NAD(+) + H(2)O <=> an acid + NADH; aldehyde dehydrogenase 655834 9796715 AARI_05900 Arthrobacter arilaitensis Re117 aldehyde dehydrogenase YP_003915789.1 654377 D 861360 CDS YP_003915790.1 308176384 9796716 655872..656729 1 NC_014550.1 identified by similarity to protein SP:P52041 (Clostridium acetobutylicum). Reduces 3-hydroxybutanoyl- CoA to acetoacetyl-CoA; 3-hydroxybutyryl-CoA dehydrogenase 656729 hbd 9796716 hbd Arthrobacter arilaitensis Re117 3-hydroxybutyryl-CoA dehydrogenase YP_003915790.1 655872 D 861360 CDS YP_003915791.1 308176385 9793946 complement(656818..657252) 1 NC_014550.1 hypothetical protein 657252 9793946 AARI_05920 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915791.1 656818 R 861360 CDS YP_003915792.1 308176386 9796717 657350..658435 1 NC_014550.1 hypothetical protein 658435 9796717 AARI_05930 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915792.1 657350 D 861360 CDS YP_003915793.1 308176387 9796718 658438..658905 1 NC_014550.1 match to protein domain PF03061: thioesterase superfamily; thioesterase family domain-containing protein 658905 9796718 AARI_05940 Arthrobacter arilaitensis Re117 thioesterase family domain-containing protein YP_003915793.1 658438 D 861360 CDS YP_003915794.1 308176388 9796719 658969..659823 1 NC_014550.1 identified by match to protein family PF04954. Match to protein domain PF08021. Possibly involved in removal of iron from iron-siderophore complexes; siderophore-interacting protein 659823 9796719 AARI_05950 Arthrobacter arilaitensis Re117 siderophore-interacting protein YP_003915794.1 658969 D 861360 CDS YP_003915795.1 308176389 9796720 complement(660154..660996) 1 NC_014550.1 DNA repair enzyme that hydrolyzes the deoxyribose N- glycosidic bond to excise various alkylated bases from a damaged DNA polymer; DNA-3-methyladenine glycosylase II 660996 alkA 9796720 alkA Arthrobacter arilaitensis Re117 DNA-3-methyladenine glycosylase II YP_003915795.1 660154 R 861360 CDS YP_003915796.1 308176390 9793662 complement(660998..661591) 1 NC_014550.1 DNA repair enzyme that hydrolyzes the deoxyribose N- glycosidic bond to excise various alkylated bases from a damaged DNA polymer; DNA-3-methyladenine glycosylase I 661591 tagA 9793662 tagA Arthrobacter arilaitensis Re117 DNA-3-methyladenine glycosylase I YP_003915796.1 660998 R 861360 CDS YP_003915797.1 308176391 9794421 661673..662044 1 NC_014550.1 identified by match to PF01022: bacterial regulatory protein, ArsR family. ArsR-family transcriptional regulators include several proteins that appear to dissociate from DNA in the presence of metal ions; ArsR family transcriptional regulator 662044 9794421 AARI_05980 Arthrobacter arilaitensis Re117 ArsR family transcriptional regulator YP_003915797.1 661673 D 861360 CDS YP_003915798.1 308176392 9796721 662047..662973 1 NC_014550.1 identified by similarity to protein SP:P13512 (Ralstonia metallidurans). Cation diffusion facilitator (CDF) family, Cd2+, Zn2+, Co2+ efflux permease (TC 2.A.4.1. 1). Also binds Cu2+ and Ni2+. Increase tolerance to divalent metal ions such as cadmium, zinc, and cobalt (is considered to be an efflux pump that remove these ions from cells); cobalt-zinc-cadmium resistance protein CzcD 662973 czcD 9796721 czcD Arthrobacter arilaitensis Re117 cobalt-zinc-cadmium resistance protein CzcD YP_003915798.1 662047 D 861360 CDS YP_003915799.1 308176393 9793786 663094..663843 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, lipoprotein translocase (LPT) family (TC 3.A.1.125.z). ABCISSE: ABC transporter, ATP-binding protein (ABC), o228 family (members of this family might be involved in a more general lipoprotein releasing mechanism common to all prokaryotes); ABC transporter ATP-binding subunit 663843 9793786 AARI_06000 Arthrobacter arilaitensis Re117 ABC transporter ATP-binding subunit YP_003915799.1 663094 D 861360 CDS YP_003915800.1 308176394 9796722 663847..666342 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, lipoprotein translocase (LPT) family (TC 3.A.1.125.z). ABCISSE: ABC transporter, permease (IM2: 2 IM domains fused into a single polypeptide chain), o228 family (members of this family might be involved in a more general lipoprotein releasing mechanism common to all prokaryotes); ABC transporter inner membrane subunit 666342 9796722 AARI_06010 Arthrobacter arilaitensis Re117 ABC transporter inner membrane subunit YP_003915800.1 663847 D 861360 CDS YP_003915801.1 308176395 9796723 666437..666781 1 NC_014550.1 hypothetical protein 666781 9796723 AARI_06020 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915801.1 666437 D 861360 CDS YP_003915802.1 308176396 9796724 complement(666857..670183) 1 NC_014550.1 hypothetical protein 670183 9796724 AARI_06030 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915802.1 666857 R 861360 CDS YP_003915803.1 308176397 9796725 complement(670187..670873) 1 NC_014550.1 hypothetical protein 670873 9796725 AARI_06040 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915803.1 670187 R 861360 CDS YP_003915804.1 308176398 9796726 complement(670870..672330) 1 NC_014550.1 hypothetical protein 672330 9796726 AARI_06050 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915804.1 670870 R 861360 CDS YP_003915805.1 308176399 9796727 672557..673813 1 NC_014550.1 signal peptide predicted by SignalP 3.0 HMM (probability: 1.000) with cleavage site probability 0.748 between position 22 and 23; hypothetical protein 673813 9796727 AARI_06060 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915805.1 672557 D 861360 CDS YP_003915806.1 308176400 9796728 complement(673835..677290) 1 NC_014550.1 hypothetical protein 677290 9796728 AARI_06070 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915806.1 673835 R 861360 CDS YP_003915807.1 308176401 9796729 complement(677368..677688) 1 NC_014550.1 3 transmembrane helices predicted by TMHMM2.0; hypothetical protein 677688 9796729 AARI_06080 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915807.1 677368 R 861360 CDS YP_003915808.1 308176402 9796730 677847..678566 1 NC_014550.1 6 transmembrane helices predicted by TMHMM2.0; hypothetical protein 678566 9796730 AARI_06090 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915808.1 677847 D 861360 CDS YP_003915809.1 308176403 9796731 complement(678549..679727) 1 NC_014550.1 PF03631 (ribonuclease_BN, ribonuclease BN-like family): this family contains integral membrane proteins with 5 to 6 predicted transmembrane spans. The family includes ribonuclease BN, which is involved in tRNA maturation; ribonuclease BN 679727 9796731 AARI_06100 Arthrobacter arilaitensis Re117 ribonuclease BN YP_003915809.1 678549 R 861360 CDS YP_003915810.1 308176404 9796732 680351..681097 1 NC_014550.1 identified by similarity to protein SP:O86308 (Micrococcus luteus). Bacterial growth factor or cytokine involved in resuscitation of dormant bacteria and stimulation of bacterial growth. Signal peptide predicted by SignalP 3.0 HMM (probability: 1.000) with cleavage site probability 0.996 between position 36 and 37; resuscitation-promoting factor 681097 9796732 AARI_06110 Arthrobacter arilaitensis Re117 resuscitation-promoting factor YP_003915810.1 680351 D 861360 CDS YP_003915811.1 308176405 9796733 681210..682580 1 NC_014550.1 CoA-transferases catalyse reversible transfer reactions of coenzyme A groups from CoA-thioesters to free acids; CoA-transferase 682580 9796733 AARI_06120 Arthrobacter arilaitensis Re117 CoA-transferase YP_003915811.1 681210 D 861360 CDS YP_003915812.1 308176406 9796734 complement(682577..683416) 1 NC_014550.1 match to PF08223: PaaX-like protein C-terminal domain. This family contains proteins that are similar to the product of the paaX gene of Escherichia coli. This protein is involved in the regulation of expression of a group of proteins known to participate in the metabolism of phenylacetic acid; PaaX-like transcriptional regulator 683416 9796734 AARI_06130 Arthrobacter arilaitensis Re117 PaaX-like transcriptional regulator YP_003915812.1 682577 R 861360 CDS YP_003915813.1 308176407 9796735 complement(683406..684272) 1 NC_014550.1 catalyses the formation of N-formylkynurenine from L-tryptophan, the first step in the kynurenine pathway (major pathway of tryptophan metabolism); tryptophan 2,3-dioxygenase 684272 kynA 9796735 kynA Arthrobacter arilaitensis Re117 tryptophan 2,3-dioxygenase YP_003915813.1 683406 R 861360 CDS YP_003915814.1 308176408 9794026 684423..685106 1 NC_014550.1 identified by match to PF03358. FMN reductase reductase catalyses the following reaction: NAD(P)H + FMN = NAD(P)(+) + FMNH(2); FMN reductase 685106 9794026 AARI_06150 Arthrobacter arilaitensis Re117 FMN reductase YP_003915814.1 684423 D 861360 CDS YP_003915815.1 308176409 9796736 685347..686132 1 NC_014550.1 identified by similarity to protein SP:P42270 (Escherichia coli). Also named OHED hydratase. Involved in the homoprotocatechuic acid pathway. Catalyses the conversion of 2-oxohept-3-ene-1,7-dioc acid into 2,4- dihydroxyhept-2-ene-1,7-dioic acid; 2-oxo-hepta-3-ene-1,7-dioic acid hydratase 686132 hpcG 9796736 hpcG Arthrobacter arilaitensis Re117 2-oxo-hepta-3-ene-1,7-dioic acid hydratase YP_003915815.1 685347 D 861360 CDS YP_003915816.1 308176410 9793973 686117..686926 1 NC_014550.1 identified by similarity to protein SP:Q47098 (Escherichia coli). Involved in the homoprotocatechuic acid pathway. Catalyses the conversion of 2,4- dihydroxyhept-2-ene-1,7-dioic acid into succinic semialdehyde and pyruvic acid; 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase 686926 hpcH 9793973 hpcH Arthrobacter arilaitensis Re117 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase YP_003915816.1 686117 D 861360 CDS YP_003915817.1 308176411 9793974 687032..688321 1 NC_014550.1 8 transmembrane helices predicted by TMHMM2.0; hypothetical protein 688321 9793974 AARI_06180 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915817.1 687032 D 861360 CDS YP_003915818.1 308176412 9796737 complement(688340..688981) 1 NC_014550.1 signal peptide predicted by SignalP 3.0 HMM (probability: 0.998) with cleavage site probability 0.256 between position 28 and 29; hypothetical protein 688981 9796737 AARI_06190 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915818.1 688340 R 861360 CDS YP_003915819.1 308176413 9796738 complement(689083..689613) 1 NC_014550.1 hypothetical protein 689613 9796738 AARI_06200 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915819.1 689083 R 861360 CDS YP_003915820.1 308176414 9796739 689764..690333 1 NC_014550.1 catalyses the NADP-dependent decarboxylative reduction of 10-formyltetrahydrofolate into tetrahydrofolate. Involved in DNA synthesis and in de novo purine biosynthesis pathway; phosphoribosylglycinamide formyltransferase 690333 purN 9796739 purN Arthrobacter arilaitensis Re117 phosphoribosylglycinamide formyltransferase YP_003915820.1 689764 D 861360 CDS YP_003915821.1 308176415 9794254 690366..691880 1 NC_014550.1 identified by match to PF00106. The short-chain dehydrogenases/reductases family (SDR) is a very large family of enzymes, most of which are known to be NAD- or NADP-dependent oxidoreductases; short-chain dehydrogenases/reductase 691880 9794254 AARI_06220 Arthrobacter arilaitensis Re117 short-chain dehydrogenases/reductase YP_003915821.1 690366 D 861360 CDS YP_003915822.1 308176416 9796740 complement(692048..695068) 1 NC_014550.1 EC 3.2.1.24 hydrolyses terminal, non-reducing alpha- D-mannose residues in alpha-D-mannosides. Also hydrolyzes alpha-D-lyxosides and heptopyranosides with the same configuration at C-2, C-3 and C-4 as mannose; alpha-mannosidase 695068 9796740 AARI_06230 Arthrobacter arilaitensis Re117 alpha-mannosidase YP_003915822.1 692048 R 861360 CDS YP_003915823.1 308176417 9796741 complement(695177..695845) 1 NC_014550.1 identified by match to protein domain PF00300; phosphoglycerate mutase family protein 695845 9796741 AARI_06240 Arthrobacter arilaitensis Re117 phosphoglycerate mutase family protein YP_003915823.1 695177 R 861360 CDS YP_003915824.1 308176418 9796742 696055..696624 1 NC_014550.1 match to PF00440: bacterial regulatory proteins, tetR family; transcriptional regulator 696624 9796742 AARI_06250 Arthrobacter arilaitensis Re117 transcriptional regulator YP_003915824.1 696055 D 861360 CDS YP_003915825.1 308176419 9796743 complement(696629..697966) 1 NC_014550.1 major facilitator superfamily (MFS), aromatic acid:H+ symporter (AAHS) family (TC 2.A.1.15.z). Members of this family transport compounds such as benzoate, hydroxybenzoate, niacin...; aromatic acid transporter 697966 9796743 AARI_06260 Arthrobacter arilaitensis Re117 aromatic acid transporter YP_003915825.1 696629 R 861360 CDS YP_003915826.1 308176420 9796744 698115..698891 1 NC_014550.1 hypothetical protein 698891 9796744 AARI_06270 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915826.1 698115 D 861360 CDS YP_003915827.1 308176421 9796745 698989..700659 1 NC_014550.1 catalyses the last two steps in de novo purine biosynthesis. Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) catalyses the formylation of AICAR with 10-formyl-tetrahydrofolate to yield FAICAR (5-formylaminoimidazole-4-carboxamide ribonucleotide) and tetrahydrofolate. IMP cyclohydrolase (EC 3.5.4.10) catalyses the formation of IMP from FAICAR; bifunctional purine biosynthesis protein PurH 700659 purH 9796745 purH Arthrobacter arilaitensis Re117 bifunctional purine biosynthesis protein PurH YP_003915827.1 698989 D 861360 CDS YP_003915828.1 308176422 9794250 complement(700814..700918) 1 NC_014550.1 hypothetical protein 700918 9794250 AARI_06290 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915828.1 700814 R 861360 CDS YP_003915829.1 308176423 9796746 701018..701149 1 NC_014550.1 hypothetical protein 701149 9796746 AARI_06300 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915829.1 701018 D 861360 CDS YP_003915830.1 308176424 9796747 complement(701254..704163) 1 NC_014550.1 match to PF02687: this is a family of predicted permeases and hypothetical transmembrane proteins; permease 704163 9796747 AARI_06310 Arthrobacter arilaitensis Re117 permease YP_003915830.1 701254 R 861360 CDS YP_003915831.1 308176425 9796748 complement(704166..704891) 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, lipoprotein translocase (LPT) family (TC 3.A.1.125.z). ABCISSE: ABC transporter, ATP-binding protein (ABC), o228 family (members of this family might be involved in a more general lipoprotein releasing mechanism common to all prokaryotes); ABC transporter ATP-binding subunit 704891 9796748 AARI_06320 Arthrobacter arilaitensis Re117 ABC transporter ATP-binding subunit YP_003915831.1 704166 R 861360 CDS YP_003915832.1 308176426 9796749 complement(704888..705442) 1 NC_014550.1 identified by match to protein family PF03551; PadR-like family transcriptional regulator 705442 9796749 AARI_06330 Arthrobacter arilaitensis Re117 PadR-like family transcriptional regulator YP_003915832.1 704888 R 861360 CDS YP_003915833.1 308176427 9796750 705713..706930 1 NC_014550.1 metal ion (Mn2+-iron) transporter (Nramp) family protein (TC 2.A.55.y.z). The generalized transport reaction catalyzed by Nramp family proteins is: Me2+ (out) + H+ (out) -> Me2+ (in) + H+ (in); divalent metal ion transporter 706930 9796750 AARI_06340 Arthrobacter arilaitensis Re117 divalent metal ion transporter YP_003915833.1 705713 D 861360 CDS YP_003915834.1 308176428 9796751 706944..707753 1 NC_014550.1 hypothetical protein 707753 9796751 AARI_06350 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915834.1 706944 D 861360 CDS YP_003915835.1 308176429 9797158 complement(709022..710014) 1 NC_014550.1 catalyzes the irreversible hydrolytic deamination of adenosine to ammonia and inosine, or of desoxyadenosine to ammonia and desoxyinosine; adenosine deaminase 710014 add 9797158 add Arthrobacter arilaitensis Re117 adenosine deaminase YP_003915835.1 709022 R 861360 CDS YP_003915836.1 308176430 9793657 complement(710393..711070) 1 NC_014550.1 identified by match to protein family PF00392. This family of regulatory proteins consists of the N-terminal HTH region of GntR-like bacterial transcription factors. At the C-terminus there is usually an effector- binding/oligomerisation domain. The GntR-like proteins can be divided into six sub-families: MocR, YtrR, FadR, AraR, HutC and PlmA. Many of these proteins have been shown experimentally to be autoregulatory, enabling the prediction of operator sites and the discovery of cis/trans relationships; GntR family transcriptional regulator 711070 9793657 AARI_06370 Arthrobacter arilaitensis Re117 GntR family transcriptional regulator YP_003915836.1 710393 R 861360 CDS YP_003915837.1 308176431 9796753 complement(711123..712862) 1 NC_014550.1 enzymes named acetyl-coenzyme A carboxylase (EC 6.4. 1.2), propionyl-coenzyme A carboxylase (EC 6.4.1.3) and acyl-coenzyme A carboxylase are constituted by several types of subunits. Alpha subunits contains the biotin carboxylase (BC, EC 6.3.4.14) and biotin carboxyl carrier protein (BCCP) domains, beta subunits contain the carboxyltransferase (CT) domain. An epsilon subunit is present in some microorganisms; acetyl-/propionyl-coenzyme A carboxylase subunit alpha 712862 9796753 AARI_06380 Arthrobacter arilaitensis Re117 acetyl-/propionyl-coenzyme A carboxylase subunit alpha YP_003915837.1 711123 R 861360 CDS YP_003915838.1 308176432 9796754 complement(712871..714475) 1 NC_014550.1 identified by match to PF02626 and PF02682. EC 3.5. 1.24 may be involved in the degradation of urea, together with EC 6.3.4.6, or in cyanuric acid metabolism; allophanate hydrolase 714475 9796754 AARI_06390 Arthrobacter arilaitensis Re117 allophanate hydrolase YP_003915838.1 712871 R 861360 CDS YP_003915839.1 308176433 9796755 complement(714472..715230) 1 NC_014550.1 identified by match to protein family PF03746. This family includes LamB. The lam locus of Aspergillus nidulans consists of two divergently transcribed genes, lamA and lamB, involved in the utilisation of lactams such as 2-pyrrolidinone; LamB/YcsF family protein 715230 9796755 AARI_06400 Arthrobacter arilaitensis Re117 LamB/YcsF family protein YP_003915839.1 714472 R 861360 CDS YP_003915840.1 308176434 9796756 complement(715438..715584) 1 NC_014550.1 hypothetical protein 715584 9796756 AARI_06410 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915840.1 715438 R 861360 CDS YP_003915841.1 308176435 9796757 complement(715746..717428) 1 NC_014550.1 catalyses the following reaction: ATP + formate + tetrahydrofolate => ADP + phosphate + 10- formyltetrahydrofolate; formate--tetrahydrofolate ligase 717428 fhs 9796757 fhs Arthrobacter arilaitensis Re117 formate--tetrahydrofolate ligase YP_003915841.1 715746 R 861360 CDS YP_003915842.1 308176436 9793849 complement(717764..719224) 1 NC_014550.1 major facilitator superfamily, drug:H+ antiporter-2 (14 spanner) (DHA2) family (TC 2.A.1.3.z). Identified by match to protein family TIGR00711; EmrB/QacA subfamily drug resistance transporter 719224 9793849 AARI_06430 Arthrobacter arilaitensis Re117 EmrB/QacA subfamily drug resistance transporter YP_003915842.1 717764 R 861360 CDS YP_003915843.1 308176437 9796839 719373..719966 1 NC_014550.1 match to PF00440: bacterial regulatory proteins, tetR family; transcriptional regulator 719966 9796839 AARI_06440 Arthrobacter arilaitensis Re117 transcriptional regulator YP_003915843.1 719373 D 861360 CDS YP_003915844.1 308176438 9796840 720180..722402 1 NC_014550.1 involved in the TCA cycle. Catalyses the interconversion of isocitrate and 2-oxoglutarate. Oxalosuccinate can also be used as a substrate; isocitrate dehydrogenase 722402 icd 9796840 icd Arthrobacter arilaitensis Re117 isocitrate dehydrogenase YP_003915844.1 720180 D 861360 CDS YP_003915845.1 308176439 9793996 722536..722811 1 NC_014550.1 hypothetical protein 722811 9793996 AARI_06460 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915845.1 722536 D 861360 CDS YP_003915846.1 308176440 9796841 722798..723535 1 NC_014550.1 hypothetical protein 723535 9796841 AARI_06470 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915846.1 722798 D 861360 CDS YP_003915847.1 308176441 9796842 complement(723758..724252) 1 NC_014550.1 hypothetical protein 724252 9796842 AARI_06480 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915847.1 723758 R 861360 CDS YP_003915848.1 308176442 9796843 complement(724268..724726) 1 NC_014550.1 hypothetical protein 724726 9796843 AARI_06490 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915848.1 724268 R 861360 CDS YP_003915849.1 308176443 9796844 724762..724911 1 NC_014550.1 hypothetical protein 724911 9796844 AARI_06500 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915849.1 724762 D 861360 CDS YP_003915850.1 308176444 9796845 724972..725997 1 NC_014550.1 match to protein domain PF00075 (RNase H). This domain is often associated with reverse transcriptases (important enzyme in retroviral replication cycle); reverse transcriptase 725997 9796845 AARI_06510 Arthrobacter arilaitensis Re117 reverse transcriptase YP_003915850.1 724972 D 861360 CDS YP_003915851.1 308176445 9796846 complement(726071..727603) 1 NC_014550.1 dGTPase catalyses the formation of deoxyguanosine from dGTP. It is involved in purine metabolism; dGTPase 727603 dgt 9796846 dgt Arthrobacter arilaitensis Re117 dGTPase YP_003915851.1 726071 R 861360 CDS YP_003915852.1 308176446 9793809 complement(727738..728766) 1 NC_014550.1 D-isomer specific 2-hydroxyacid dehydrogenase family protein 728766 9793809 AARI_06530 Arthrobacter arilaitensis Re117 D-isomer specific 2-hydroxyacid dehydrogenase family protein YP_003915852.1 727738 R 861360 CDS YP_003915853.1 308176447 9796847 728816..729019 1 NC_014550.1 hypothetical protein 729019 9796847 AARI_06540 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915853.1 728816 D 861360 CDS YP_003915854.1 308176448 9796848 complement(729063..729632) 1 NC_014550.1 hypothetical protein 729632 9796848 AARI_06550 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915854.1 729063 R 861360 CDS YP_003915855.1 308176449 9796849 complement(729916..731214) 1 NC_014550.1 match to PF00196: bacterial regulatory proteins, luxR family. This domain is a DNA-binding, helix-turn- helix (HTH) domain of about 65 amino acids, present in transcription regulators of the LuxR/FixJ family of response regulators; hypothetical protein 731214 9796849 AARI_06560 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915855.1 729916 R 861360 CDS YP_003915856.1 308176450 9796850 731376..731972 1 NC_014550.1 identified by similarity to protein SP:Q9LBW5 (Mycobacterium gastri). Catalyzes the isomerization of the D-arabino-3-hexulose 6-phosphate into fructose 6-phosphate in microorganisms that can use formaldehyde as a carbon source (ribulose monophosphate pathway of formaldehyde fixation); 3-hexulose-6-phosphate isomerase 731972 rmpB 9796850 rmpB Arthrobacter arilaitensis Re117 3-hexulose-6-phosphate isomerase YP_003915856.1 731376 D 861360 CDS YP_003915857.1 308176451 9794303 732030..732653 1 NC_014550.1 identified by similarity to protein SP:Q9LBW4 (Mycobacterium gastri). Catalyzes the formation of D- arabino-3-hexulose-6-phosphate from D-ribulose 5-phosphate and formaldehyde in microorganisms that can use formaldehyde as a carbon source (ribulose monophosphate pathway of formaldehyde fixation); 3-hexulose-6-phosphate synthase 732653 rmpA 9794303 rmpA Arthrobacter arilaitensis Re117 3-hexulose-6-phosphate synthase YP_003915857.1 732030 D 861360 CDS YP_003915858.1 308176452 9796855 complement(734827..735510) 1 NC_014550.1 cd00038: effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO sensor. In all cases binding of the effector leads to conformational changes and the ability to activate transcription; Crp/Fnr family transcriptional regulator 735510 9796855 AARI_06640 Arthrobacter arilaitensis Re117 Crp/Fnr family transcriptional regulator YP_003915858.1 734827 R 861360 CDS YP_003915859.1 308176453 9796856 735681..735920 1 NC_014550.1 chaperone that serves for the intracellular sequestration and transport of Cu(+). Delivers Cu(+) to the copper-transporting ATPase CopA. Identified by similarity to protein SP:O32221 (Bacillus subtilis); copper chaperone CopZ 735920 copZ 9796856 copZ Arthrobacter arilaitensis Re117 copper chaperone CopZ YP_003915859.1 735681 D 861360 CDS YP_003915860.1 308176454 9793756 736015..738018 1 NC_014550.1 involved in copper export. Forms an heterodimer with CopZ during the transfer of Cu(+). TCDB: P-type ATPase (P-ATPase) superfamily (TC 3.A.3.y.z). Identified by similarity to protein SP:O32220 (Bacillus subtilis); copper-exporting ATPase CopA 738018 copA 9793756 copA Arthrobacter arilaitensis Re117 copper-exporting ATPase CopA YP_003915860.1 736015 D 861360 CDS YP_003915861.1 308176455 9793755 738124..738549 1 NC_014550.1 presence of one conserved barrel domain of the cupin superfamily (PF07883); barrel domain-containing protein 738549 9793755 AARI_06670 Arthrobacter arilaitensis Re117 barrel domain-containing protein YP_003915861.1 738124 D 861360 CDS YP_003915862.1 308176456 9796857 complement(739016..739891) 1 NC_014550.1 PF02012: BNR/Asp-box repeats. These repeats are found in a variety of non-homologous proteins, including bacterial ribonucleases, sulphite oxidases, reelin, netrins, sialidases, neuraminidases, some lipoprotein receptors, and a variety of glycosyl hydrolases. Similar to protein SP:Q6SK52 (Arthrobacter aurescens plasmid); hypothetical protein 739891 9796857 AARI_06680 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915862.1 739016 R 861360 CDS YP_003915863.1 308176457 9796858 complement(739976..740581) 1 NC_014550.1 signal peptide predicted by SignalP 3.0 HMM (probability: 0.999) with cleavage site probability 0.520 between position 25 and 26. Similar to protein SP:A1RCQ1 (Arthrobacter aurescens plasmid); hypothetical protein 740581 9796858 AARI_06690 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915863.1 739976 R 861360 CDS YP_003915864.1 308176458 9796859 complement(740703..741176) 1 NC_014550.1 2 transmembrane helices predicted by TMHMM2.0. Similar to protein SP:A1RCQ0 (Arthrobacter aurescens plasmid); hypothetical protein 741176 9796859 AARI_06700 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915864.1 740703 R 861360 CDS YP_003915865.1 308176459 9796860 complement(741276..743447) 1 NC_014550.1 P-type ATPase (P-ATPase) superfamily (TC 3.A.3.y.z). Involved in export of cations; cation-transporting ATPase 743447 9796860 AARI_06710 Arthrobacter arilaitensis Re117 cation-transporting ATPase YP_003915865.1 741276 R 861360 CDS YP_003915866.1 308176460 9796861 743608..744036 1 NC_014550.1 1 transmembrane helice predicted by TMHMM2.0; hypothetical protein 744036 9796861 AARI_06720 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915866.1 743608 D 861360 CDS YP_003915867.1 308176461 9796863 complement(744871..746811) 1 NC_014550.1 TCDB: P-type ATPase (P-ATPase) superfamily (TC 3.A. 3.y.z). Possibly involved in export of cations; cation-transporting ATPase 746811 9796863 AARI_06740 Arthrobacter arilaitensis Re117 cation-transporting ATPase YP_003915867.1 744871 R 861360 CDS YP_003915868.1 308176462 9796864 complement(746808..747176) 1 NC_014550.1 identified by match to PF01022: bacterial regulatory protein, ArsR family. ArsR-family transcriptional regulators include several proteins that appear to dissociate from DNA in the presence of metal ions; ArsR family transcriptional regulator 747176 9796864 AARI_06750 Arthrobacter arilaitensis Re117 ArsR family transcriptional regulator YP_003915868.1 746808 R 861360 CDS YP_003915869.1 308176463 9796865 747392..747637 1 NC_014550.1 hypothetical protein 747637 9796865 AARI_06760 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915869.1 747392 D 861360 CDS YP_003915870.1 308176464 9796866 747634..748434 1 NC_014550.1 identified by match to PF02661: Fic protein family. cAMP may be a regulation factor in cell division of some bacteria. The Fic (filamentation induced by cAMP) protein is involved in the synthesis of PAB or folate. It would appear that the Fic protein and cAMP are involved in a regulatory mechanism of cell division via folate metabolism and in these organisms cell division could be controlled by coordination of cAMP, Fic and Fts proteins; Fic family protein 748434 9796866 AARI_06770 Arthrobacter arilaitensis Re117 Fic family protein YP_003915870.1 747634 D 861360 CDS YP_003915871.1 308176465 9796867 748431..749105 1 NC_014550.1 match to PF00239 and PF02796. Possibly involved in site-specific recombination of DNA; resolvase 749105 9796867 AARI_06780 Arthrobacter arilaitensis Re117 resolvase YP_003915871.1 748431 D 861360 CDS YP_003915872.1 308176466 9796868 complement(749402..749797) 1 NC_014550.1 hypothetical protein 749797 9796868 AARI_06790 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915872.1 749402 R 861360 CDS YP_003915873.1 308176467 9796869 750004..750459 1 NC_014550.1 identified by match to protein family PF05713: bacterial mobilisation protein (MobC). This family consists of several bacterial MobC-like, mobilisation proteins. MobC proteins belong to the group of relaxases. Together with MobA and MobB they bind to a single cis- active site of a mobilising plasmid, the origin of transfer (oriT) region; mobilisation protein 750459 9796869 AARI_06800 Arthrobacter arilaitensis Re117 mobilisation protein YP_003915873.1 750004 D 861360 CDS YP_003915874.1 308176468 9796870 750456..752171 1 NC_014550.1 identified by match to protein family PF03432: Relaxase/Mobilisation nuclease domain. Relaxases/mobilisation proteins are required for the horizontal transfer of genetic information contained on plasmids that occurs during bacterial conjugation; mobilisation protein 752171 9796870 AARI_06810 Arthrobacter arilaitensis Re117 mobilisation protein YP_003915874.1 750456 D 861360 CDS YP_003915875.1 308176469 9796871 752187..753047 1 NC_014550.1 similar to Arthrobacter plasmidic proteins; hypothetical protein 753047 9796871 AARI_06820 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915875.1 752187 D 861360 CDS YP_003915876.1 308176470 9796872 753359..754717 1 NC_014550.1 signal peptide predicted by SignalP 3.0 HMM (probability: 1.000) with cleavage site probability 0.990 between position 30 and 31; hypothetical protein 754717 9796872 AARI_06830 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915876.1 753359 D 861360 CDS YP_003915877.1 308176471 9796873 754792..755199 1 NC_014550.1 4 transmembrane helices predicted by TMHMM2.0; hypothetical protein 755199 9796873 AARI_06840 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915877.1 754792 D 861360 CDS YP_003915878.1 308176472 9796874 complement(755360..755722) 1 NC_014550.1 3 transmembrane helices predicted by TMHMM2.0; hypothetical protein 755722 9796874 AARI_06850 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915878.1 755360 R 861360 CDS YP_003915879.1 308176473 9796875 complement(755757..756506) 1 NC_014550.1 hypothetical protein 756506 9796875 AARI_06860 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915879.1 755757 R 861360 CDS YP_003915880.1 308176474 9796878 complement(758702..759310) 1 NC_014550.1 acyl-CoA acyltransferase domain-containing protein 759310 9796878 AARI_06890 Arthrobacter arilaitensis Re117 acyl-CoA acyltransferase domain-containing protein YP_003915880.1 758702 R 861360 CDS YP_003915881.1 308176475 9796879 complement(759511..760632) 1 NC_014550.1 hypothetical protein 760632 9796879 AARI_06900 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915881.1 759511 R 861360 CDS YP_003915882.1 308176476 9796880 complement(761249..761773) 1 NC_014550.1 1 transmembrane helice predicted by TMHMM2.0; hypothetical protein 761773 9796880 AARI_06910 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915882.1 761249 R 861360 CDS YP_003915883.1 308176477 9796881 complement(762001..762849) 1 NC_014550.1 IPR001478; PDZ domains are found in diverse signaling proteins in bacteria, yeasts, plants, insects and vertebrates; PDZ domain-containing protein 762849 9796881 AARI_06920 Arthrobacter arilaitensis Re117 PDZ domain-containing protein YP_003915883.1 762001 R 861360 CDS YP_003915884.1 308176478 9796882 763759..765096 1 NC_014550.1 identified by similarity to protein SP:Q6DKY2 (Bacillus stearothermophilus). Heat-stable reverse transcriptase. Possible group II intron associated protein; reverse transcriptase/maturase 765096 trt 9796882 trt Arthrobacter arilaitensis Re117 reverse transcriptase/maturase YP_003915884.1 763759 D 861360 CDS YP_003915885.1 308176479 9794474 765331..766038 1 NC_014550.1 hypothetical protein 766038 9794474 AARI_06940 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915885.1 765331 D 861360 CDS YP_003915886.1 308176480 9796883 complement(766062..767339) 1 NC_014550.1 transposase of ISAar15, ISL3 family 767339 9796883 AARI_34570 Arthrobacter arilaitensis Re117 transposase of ISAar15, ISL3 family YP_003915886.1 766062 R 861360 CDS YP_003915887.1 308176481 9797159 complement(767420..768499) 1 NC_014550.1 transposase of ISAar16, IS110 family 768499 9797159 AARI_34580 Arthrobacter arilaitensis Re117 transposase of ISAar16, IS110 family YP_003915887.1 767420 R 861360 CDS YP_003915888.1 308176482 9797160 768891..769151 1 NC_014550.1 1 transmembrane helice predicted by TMHMM2.0; hypothetical protein 769151 9797160 AARI_06950 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915888.1 768891 D 861360 CDS YP_003915889.1 308176483 9796884 complement(769232..769774) 1 NC_014550.1 identified by match to PF01613; flavin reductase-like domain protein 769774 9796884 AARI_06960 Arthrobacter arilaitensis Re117 flavin reductase-like domain protein YP_003915889.1 769232 R 861360 CDS YP_003915890.1 308176484 9796885 complement(769767..770807) 1 NC_014550.1 final step in methionine synthesis; 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 770807 metE 9796885 metE Arthrobacter arilaitensis Re117 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase YP_003915890.1 769767 R 861360 CDS YP_003915891.1 308176485 9794070 complement(770826..771818) 1 NC_014550.1 hypothetical protein 771818 9794070 AARI_06980 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915891.1 770826 R 861360 CDS YP_003915892.1 308176486 9796886 771941..773071 1 NC_014550.1 identified by match to PF00126: bacterial regulatory helix-turn-helix protein, lysR family. Numerous bacterial transcription regulatory proteins bind DNA via a helix-turn-helix (HTH) motif. These proteins are very diverse, but for convenience may be grouped into subfamilies on the basis of sequence similarity. One such family, the lysR family, groups together a range of proteins, including ampR, catM, catR, cynR, cysB, gltC, iciA, ilvY, irgB, lysR, metR, mkaC, mleR, nahR, nhaR, nodD, nolR, oxyR, pssR, rbcR, syrM, tcbR, tfdS and trpI. The majority of these proteins appear to be transcription activators and most are known to negatively regulate their own expression. All possess a potential HTH DNA-binding motif towards their N-termini; LysR family transcriptional regulator 773071 9796886 AARI_06990 Arthrobacter arilaitensis Re117 LysR family transcriptional regulator YP_003915892.1 771941 D 861360 CDS YP_003915893.1 308176487 9796887 773295..774608 1 NC_014550.1 catalyses several reactions, including the formation of L-homocysteine from O-acetyl-L-homoserine and H2S, and the formation of L-methionine from O-acetyl-L- homoserine and methanethiol; O-acetylhomoserine aminocarboxypropyltransferase 774608 9796887 AARI_07000 Arthrobacter arilaitensis Re117 O-acetylhomoserine aminocarboxypropyltransferase YP_003915893.1 773295 D 861360 CDS YP_003915894.1 308176488 9796888 774605..775828 1 NC_014550.1 catalyzes the conversion of cysteine and succinyl- homoserine into cystathionine and succinate. Several other reactions may also be catalysed in some organisms; cystathionine gamma-synthase 775828 metB 9796888 metB Arthrobacter arilaitensis Re117 cystathionine gamma-synthase YP_003915894.1 774605 D 861360 CDS YP_003915895.1 308176489 9796889 complement(776416..777030) 1 NC_014550.1 match to PF00132: Bacterial transferase hexapeptide repeat. A number of different transferase protein families contain this repeat, such as galactoside acetyltransferase- like proteins, the gamma-class of carbonic anhydrases, and tetrahydrodipicolinate-N-succinlytransferases; transferase 777030 9796889 AARI_07030 Arthrobacter arilaitensis Re117 transferase YP_003915895.1 776416 R 861360 CDS YP_003915896.1 308176490 9796890 complement(777083..777448) 1 NC_014550.1 1 transmembrane helice predicted by TMHMM2.0; hypothetical protein 777448 9796890 AARI_07040 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915896.1 777083 R 861360 CDS YP_003915897.1 308176491 9796891 complement(777451..778293) 1 NC_014550.1 catalyses the following reaction: 10- formyltetrahydrofolate + H(2)O <=> formate + tetrahydrofolate; formyltetrahydrofolate deformylase 778293 purU 9796891 purU Arthrobacter arilaitensis Re117 formyltetrahydrofolate deformylase YP_003915897.1 777451 R 861360 CDS YP_003915898.1 308176492 9796892 779557..780420 1 NC_014550.1 methylenetetrahydrofolate dehydrogenase (EC 1.5.1. 5) catalyses the following reaction: 5,10- methylenetetrahydrofolate + NADP(+) <=> 5,10- methenyltetrahydrofolate + NADPH. Methylenetetrahydrofolate cyclohydrolase (EC 3.5.4.9) catalyses the following reaction: 5,10- methenyltetrahydrofolate + H(2)O <=> 10- formyltetrahydrofolate methenyltetrahydrofolate cyclohydrolase; bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 780420 folD 9796892 folD Arthrobacter arilaitensis Re117 bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase YP_003915898.1 779557 D 861360 CDS YP_003915899.1 308176493 9793859 complement(780559..781944) 1 NC_014550.1 major facilitator superfamily (MFS), metabolite:H+ symporter (MHS) family (TC 2.A.1.6.z); MFS superfamily transporter 781944 9793859 AARI_07080 Arthrobacter arilaitensis Re117 MFS superfamily transporter YP_003915899.1 780559 R 861360 CDS YP_003915900.1 308176494 9796893 782072..782971 1 NC_014550.1 identified by match to PF00126: bacterial regulatory helix-turn-helix protein, lysR family. Numerous bacterial transcription regulatory proteins bind DNA via a helix-turn-helix (HTH) motif. These proteins are very diverse, but for convenience may be grouped into subfamilies on the basis of sequence similarity. One such family, the lysR family, groups together a range of proteins, including ampR, catM, catR, cynR, cysB, gltC, iciA, ilvY, irgB, lysR, metR, mkaC, mleR, nahR, nhaR, nodD, nolR, oxyR, pssR, rbcR, syrM, tcbR, tfdS and trpI. The majority of these proteins appear to be transcription activators and most are known to negatively regulate their own expression. All possess a potential HTH DNA-binding motif towards their N-termini; LysR family transcriptional regulator 782971 9796893 AARI_07090 Arthrobacter arilaitensis Re117 LysR family transcriptional regulator YP_003915900.1 782072 D 861360 CDS YP_003915901.1 308176495 9796894 783004..783360 1 NC_014550.1 hypothetical protein 783360 9796894 AARI_07100 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915901.1 783004 D 861360 CDS YP_003915902.1 308176496 9796895 complement(783308..783970) 1 NC_014550.1 response regulators are key elements in two- component signal transduction systems, which enable bacteria to sense, respond, and adapt to a wide range of environments, stressors, and growth conditions; two-component system response regulator 783970 9796895 AARI_07110 Arthrobacter arilaitensis Re117 two-component system response regulator YP_003915902.1 783308 R 861360 CDS YP_003915903.1 308176497 9796896 complement(783967..785130) 1 NC_014550.1 protein-histidine kinases are key elements in two- component signal transduction systems, which enable bacteria to sense, respond, and adapt to a wide range of environments, stressors, and growth conditions; signal transduction histidine kinase 785130 9796896 AARI_07120 Arthrobacter arilaitensis Re117 signal transduction histidine kinase YP_003915903.1 783967 R 861360 CDS YP_003915904.1 308176498 9796897 785240..786022 1 NC_014550.1 6 transmembrane helices predicted by TMHMM2.0; hypothetical protein 786022 9796897 AARI_07130 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915904.1 785240 D 861360 CDS YP_003915905.1 308176499 9796898 786092..786589 1 NC_014550.1 2 transmembrane helices predicted by TMHMM2.0; hypothetical protein 786589 9796898 AARI_07140 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915905.1 786092 D 861360 CDS YP_003915906.1 308176500 9796899 786692..787531 1 NC_014550.1 removes the damaged DNA at cytosines and guanines by cleaving on the 3 -side of the apurinic/apyrimidinic sites; exodeoxyribonuclease III 787531 9796899 AARI_07150 Arthrobacter arilaitensis Re117 exodeoxyribonuclease III YP_003915906.1 786692 D 861360 CDS YP_003915907.1 308176501 9796900 787540..788556 1 NC_014550.1 activates tryptophan and transfers it to tRNA(Trp) as the first step in protein biosynthesis; tryptophan--tRNA ligase 788556 trpS 9796900 trpS Arthrobacter arilaitensis Re117 tryptophan--tRNA ligase YP_003915907.1 787540 D 861360 CDS YP_003915908.1 308176502 9794473 788556..789068 1 NC_014550.1 match to PF02834. Corresponds to a number of known and predicted phosphoesterases, including bacterial and archaeal 2 ,5 RNA ligases. The physiological substrate(s) in prokaryotes may include small 2 ,5 -link-containing oligonucleotides, perhaps with regulatory or biosynthetic roles; 2',5' RNA ligase 789068 9794473 AARI_07170 Arthrobacter arilaitensis Re117 2',5' RNA ligase YP_003915908.1 788556 D 861360 CDS YP_003915909.1 308176503 9796901 complement(789114..790568) 1 NC_014550.1 decomposes hydrogen peroxide to molecular oxygen and water. Its main function is to protect cells from the toxic effects of hydrogen peroxide; catalase 790568 9796901 AARI_07180 Arthrobacter arilaitensis Re117 catalase YP_003915909.1 789114 R 861360 CDS YP_003915910.1 308176504 9796902 complement(791662..792939) 1 NC_014550.1 transposase of ISAar15, ISL3 family 792939 9796902 AARI_34590 Arthrobacter arilaitensis Re117 transposase of ISAar15, ISL3 family YP_003915910.1 791662 R 861360 CDS YP_003915911.1 308176505 9797161 complement(793020..794099) 1 NC_014550.1 transposase of ISAar16, IS110 family 794099 9797161 AARI_34600 Arthrobacter arilaitensis Re117 transposase of ISAar16, IS110 family YP_003915911.1 793020 R 861360 CDS YP_003915912.1 308176506 9797162 complement(795611..796918) 1 NC_014550.1 transposase of ISAar19, ISL3 family 796918 9797162 AARI_34610 Arthrobacter arilaitensis Re117 transposase of ISAar19, ISL3 family YP_003915912.1 795611 R 861360 CDS YP_003915913.1 308176507 9793405 798815..799813 1 NC_014550.1 9 transmembrane helices predicted by TMHMM2.0; hypothetical protein 799813 9793405 AARI_07190 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915913.1 798815 D 861360 CDS YP_003915914.1 308176508 9796903 complement(799879..800661) 1 NC_014550.1 the succinate dehydrogenase complex catalyses the interconversion of fumarate and succinate. It contains several subunits: a flavoprotein (SdhA), an iron-sulfur protein (SdhB), and membrane anchor proteins (SdhC and SdhD). Involved in the TCA cycle; succinate dehydrogenase iron-sulfur subunit 800661 sdhB 9796903 sdhB Arthrobacter arilaitensis Re117 succinate dehydrogenase iron-sulfur subunit YP_003915914.1 799879 R 861360 CDS YP_003915915.1 308176509 9794383 complement(800661..802448) 1 NC_014550.1 the succinate dehydrogenase complex catalyses the interconversion of fumarate and succinate. It contains several subunits: a flavoprotein (SdhA), an iron-sulfur protein (SdhB), and membrane anchor proteins (SdhC and SdhD). Involved in the TCA cycle; succinate dehydrogenase flavoprotein subunit 802448 sdhA 9794383 sdhA Arthrobacter arilaitensis Re117 succinate dehydrogenase flavoprotein subunit YP_003915915.1 800661 R 861360 CDS YP_003915916.1 308176510 9794381 complement(802506..802949) 1 NC_014550.1 the succinate dehydrogenase complex catalyses the interconversion of fumarate and succinate. It contains several subunits: a flavoprotein (SdhA), an iron-sulfur protein (SdhB), and membrane anchor proteins (SdhC and SdhD). Involved in the TCA cycle; succinate dehydrogenase membrane subunit 802949 sdhD 9794381 sdhD Arthrobacter arilaitensis Re117 succinate dehydrogenase membrane subunit YP_003915916.1 802506 R 861360 CDS YP_003915917.1 308176511 9794385 complement(802953..803333) 1 NC_014550.1 the succinate dehydrogenase complex catalyses the interconversion of fumarate and succinate. It contains several subunits: a flavoprotein (SdhA), an iron-sulfur protein (SdhB), and membrane anchor proteins (SdhC and SdhD). Involved in the TCA cycle; succinate dehydrogenase membrane subunit 803333 sdhC 9794385 sdhC Arthrobacter arilaitensis Re117 succinate dehydrogenase membrane subunit YP_003915917.1 802953 R 861360 CDS YP_003915918.1 308176512 9794384 803613..804728 1 NC_014550.1 catalyses the following reaction: GDP + alpha-D- mannose 1-phosphate <=> phosphate + GDP-mannose. Participates in fructose and mannose metabolism; mannose-1-phosphate guanylyltransferase 804728 manC 9794384 manC Arthrobacter arilaitensis Re117 mannose-1-phosphate guanylyltransferase YP_003915918.1 803613 D 861360 CDS YP_003915919.1 308176513 9794057 804878..807022 1 NC_014550.1 identified by similarity to protein SP:P0ABC9 (Escherichia coli). Betaine/carnitine/choline fransporter (BCCT) family, choline:H+ symporter (TC 2.A.15.3.1). Involved in the osmoregulatory choline-glycine betaine pathway (choline uptake); high-affinity choline transport protein 807022 betT 9794057 betT Arthrobacter arilaitensis Re117 high-affinity choline transport protein YP_003915919.1 804878 D 861360 CDS YP_003915920.1 308176514 9793712 807019..808545 1 NC_014550.1 involved in the synthesis of the osmoprotectant betaine; betaine-aldehyde dehydrogenase 808545 betB 9793712 betB Arthrobacter arilaitensis Re117 betaine-aldehyde dehydrogenase YP_003915920.1 807019 D 861360 CDS YP_003915921.1 308176515 9793711 808563..810134 1 NC_014550.1 catalyzes the following reaction: choline + O2 <=> betaine aldehyde + H2O2. Involved in the synthesis of the osmoprotectant betaine; choline oxidase 810134 codA 9793711 codA Arthrobacter arilaitensis Re117 choline oxidase YP_003915921.1 808563 D 861360 CDS YP_003915922.1 308176516 9793754 810281..811477 1 NC_014550.1 metal-dependent amidase/aminoacylase/carboxypeptidase 811477 9793754 AARI_07280 Arthrobacter arilaitensis Re117 metal-dependent amidase/aminoacylase/carboxypeptidase YP_003915922.1 810281 D 861360 CDS YP_003915923.1 308176517 9796904 811766..812854 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, carbohydrate uptake transporter-2 (CUT2) family (TC 3.A.1. 2.z). ABCISSE: ABCISSE: ABC transporter, binding protein (BP), MOS-family (monosaccharides: pentoses and hexoses); sugar ABC transporter substrate-binding protein 812854 9796904 AARI_07290 Arthrobacter arilaitensis Re117 sugar ABC transporter substrate-binding protein YP_003915923.1 811766 D 861360 CDS YP_003915924.1 308176518 9796905 812992..814590 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, carbohydrate uptake transporter-2 (CUT2) family (TC 3.A.1. 2.z). ABCISSE: ABCISSE: ABC transporter, fused ATP- binding protein (ABC2), MOS-family (monosaccharides: pentoses and hexoses); sugar ABC transporter ATP-binding subunit 814590 9796905 AARI_07300 Arthrobacter arilaitensis Re117 sugar ABC transporter ATP-binding subunit YP_003915924.1 812992 D 861360 CDS YP_003915925.1 308176519 9796906 814587..815792 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, carbohydrate uptake transporter-2 (CUT2) family (TC 3.A.1. 2.z). ABCISSE: ABCISSE: ABC transporter, permease (IM), MOS-family (monosaccharides: pentoses and hexoses); sugar ABC transporter inner membrane subunit 815792 9796906 AARI_07310 Arthrobacter arilaitensis Re117 sugar ABC transporter inner membrane subunit YP_003915925.1 814587 D 861360 CDS YP_003915926.1 308176520 9796907 815789..817060 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, carbohydrate uptake transporter-2 (CUT2) family (TC 3.A.1. 2.z). ABCISSE: ABCISSE: ABC transporter, permease (IM), MOS-family (monosaccharides: pentoses and hexoses); sugar ABC transporter inner membrane subunit 817060 9796907 AARI_07320 Arthrobacter arilaitensis Re117 sugar ABC transporter inner membrane subunit YP_003915926.1 815789 D 861360 CDS YP_003915927.1 308176521 9796908 817070..817480 1 NC_014550.1 catalyzes the hydrolysis of cytidine into uridine and ammonia; cytidine deaminase 817480 cdd 9796908 cdd Arthrobacter arilaitensis Re117 cytidine deaminase YP_003915927.1 817070 D 861360 CDS YP_003915928.1 308176522 9793732 817524..818837 1 NC_014550.1 catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate. This enzyme regulates the availability of thymidine and is therefore essential to nucleic acid metabolism; thymidine phosphorylase 818837 deoA 9793732 deoA Arthrobacter arilaitensis Re117 thymidine phosphorylase YP_003915928.1 817524 D 861360 CDS YP_003915929.1 308176523 9793802 819121..819795 1 NC_014550.1 4 transmembrane helices predicted by TMHMM2.0; hypothetical protein 819795 9793802 AARI_07350 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915929.1 819121 D 861360 CDS YP_003915930.1 308176524 9796909 819887..821080 1 NC_014550.1 catalyzes the irreversible hydrolytic deamination of adenosine to ammonia and inosine, or of desoxyadenosine to ammonia and desoxyinosine; adenosine deaminase 821080 add 9796909 add Arthrobacter arilaitensis Re117 adenosine deaminase YP_003915930.1 819887 D 861360 CDS YP_003915931.1 308176525 9793658 complement(821165..822655) 1 NC_014550.1 identified by match to protein family PF00171; aldehyde dehydrogenase family protein 822655 9793658 AARI_07370 Arthrobacter arilaitensis Re117 aldehyde dehydrogenase family protein YP_003915931.1 821165 R 861360 CDS YP_003915932.1 308176526 9796910 822766..823464 1 NC_014550.1 match to protein domain PF03819. In Escherichia coli, MazG was characterized as a nucleoside triphosphate pyrophosphohydrolase which can hydrolyze all eight of the canonical ribo- and deoxynucleoside triphosphates to their respective monophosphates and PPi, with a preference for deoxynucleotides; MazG nucleotide pyrophosphohydrolase domain-containing protein 823464 9796910 AARI_07380 Arthrobacter arilaitensis Re117 MazG nucleotide pyrophosphohydrolase domain-containing protein YP_003915932.1 822766 D 861360 CDS YP_003915933.1 308176527 9796911 823557..824837 1 NC_014550.1 other names: 2-phosphoglycerate dehydratase, 2- phospho-D-glycerate hydro-lyase. Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate; enolase 824837 eno 9796911 eno Arthrobacter arilaitensis Re117 enolase YP_003915933.1 823557 D 861360 CDS YP_003915934.1 308176528 9793835 824962..825801 1 NC_014550.1 1 transmembrane helice predicted by TMHMM2.0; hypothetical protein 825801 9793835 AARI_07400 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915934.1 824962 D 861360 CDS YP_003915935.1 308176529 9796912 825831..826532 1 NC_014550.1 hypothetical protein 826532 9796912 AARI_07410 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915935.1 825831 D 861360 CDS YP_003915936.1 308176530 9796913 826532..827458 1 NC_014550.1 identified by match to protein family PF02541. Similar to exopolyphosphatase (Ppx, EC 3.6.1.11) and guanosine pentaphosphate phospho-hydrolase (GppA, EC 3.6.1. 40) proteins; Ppx/GppA phosphatase family protein 827458 9796913 AARI_07420 Arthrobacter arilaitensis Re117 Ppx/GppA phosphatase family protein YP_003915936.1 826532 D 861360 CDS YP_003915937.1 308176531 9796914 827493..828998 1 NC_014550.1 identified by match to PF00082. Subtilases are a family of serine proteases. The vast majority of the family are endopeptidases. Signal peptide predicted by SignalP 3.0 HMM (probability: 1.000) with cleavage site probability 0.974 between position 38 and 39. 1 transmembrane helice predicted by TMHMM2.0 after the signal peptide; subtilase 828998 9796914 AARI_07430 Arthrobacter arilaitensis Re117 subtilase YP_003915937.1 827493 D 861360 CDS YP_003915938.1 308176532 9796915 829189..830556 1 NC_014550.1 NADH dehydrogenase catalyzes the following reaction: NADH + acceptor <=> NAD(+) + reduced acceptor; NADH dehydrogenase 830556 ndh 9796915 ndh Arthrobacter arilaitensis Re117 NADH dehydrogenase YP_003915938.1 829189 D 861360 CDS YP_003915939.1 308176533 9793600 831054..831860 1 NC_014550.1 6 transmembrane helices predicted by TMHMM2.0; hypothetical protein 831860 9793600 AARI_07450 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915939.1 831054 D 861360 CDS YP_003915940.1 308176534 9796916 832073..833512 1 NC_014550.1 amino acid-polyamine-organocation (APC) superfamily (TC 2.A.3.y.z); amino acid transporter 833512 9796916 AARI_07460 Arthrobacter arilaitensis Re117 amino acid transporter YP_003915940.1 832073 D 861360 CDS YP_003915941.1 308176535 9796917 833692..835023 1 NC_014550.1 match to protein family PF01594; permease 835023 9796917 AARI_07470 Arthrobacter arilaitensis Re117 permease YP_003915941.1 833692 D 861360 CDS YP_003915942.1 308176536 9796918 835027..836298 1 NC_014550.1 catalyzes the conversion of threonine into 2- oxobutanoate. Involved in isoleucine biosynthesis. The enzyme from a number of sources also acts on L-serine; threonine ammonia-lyase 836298 ilvA 9796918 ilvA Arthrobacter arilaitensis Re117 threonine ammonia-lyase YP_003915942.1 835027 D 861360 CDS YP_003915943.1 308176537 9794002 complement(836371..836868) 1 NC_014550.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; transcription elongation factor GreA 836868 greA 9794002 greA Arthrobacter arilaitensis Re117 transcription elongation factor GreA YP_003915943.1 836371 R 861360 CDS YP_003915944.1 308176538 9793935 complement(837158..837634) 1 NC_014550.1 1 transmembrane helice predicted by TMHMM2.0; hypothetical protein 837634 9793935 AARI_07500 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915944.1 837158 R 861360 CDS YP_003915945.1 308176539 9796919 837768..838685 1 NC_014550.1 LmbE-like protein 838685 9796919 AARI_07510 Arthrobacter arilaitensis Re117 LmbE-like protein YP_003915945.1 837768 D 861360 CDS YP_003915946.1 308176540 9797001 838729..839010 1 NC_014550.1 1 transmembrane helice predicted by TMHMM2.0; hypothetical protein 839010 9797001 AARI_07520 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915946.1 838729 D 861360 CDS YP_003915947.1 308176541 9797002 839043..841157 1 NC_014550.1 hypothetical protein 841157 9797002 AARI_07530 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915947.1 839043 D 861360 CDS YP_003915948.1 308176542 9797003 841275..842036 1 NC_014550.1 generates undecaprenyl pyrophosphate (UPP) from isopentenyl pyrophosphate (IPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide; di-trans,poly-cis-decaprenylcistransferase 842036 uppS1 9797003 uppS1 Arthrobacter arilaitensis Re117 di-trans,poly-cis-decaprenylcistransferase YP_003915948.1 841275 D 861360 CDS YP_003915949.1 308176543 9794492 842293..843609 1 NC_014550.1 identified by match to protein family PF02562: PhoH, PhoH-like protein. PhoH is a cytoplasmic protein and predicted ATPase that is induced by phosphate starvation; PhoH-like protein 843609 9794492 AARI_07550 Arthrobacter arilaitensis Re117 PhoH-like protein YP_003915949.1 842293 D 861360 CDS YP_003915950.1 308176544 9797004 complement(843606..844424) 1 NC_014550.1 hypothetical protein 844424 9797004 AARI_07560 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915950.1 843606 R 861360 CDS YP_003915951.1 308176545 9797005 844508..845011 1 NC_014550.1 match to PF01478: Type IV leader peptidase family. This group of aspartic endopeptidases belong to MEROPS peptidase family A24 (type IV prepilin peptidase family, clan AD), subfamily A24A. Possibly involved in protein secretion; leader peptidase 845011 9797005 AARI_07570 Arthrobacter arilaitensis Re117 leader peptidase YP_003915951.1 844508 D 861360 CDS YP_003915952.1 308176546 9797006 845016..845483 1 NC_014550.1 identified by match to PF00293. Members of the Nudix hydrolase superfamily catalyze the hydrolysis of nucleoside diphosphates linked to other moieties. Substrates of nudix hydrolases include intact and oxidatively damaged nucleoside triphosphates, dinucleoside polyphosphates, nucleotide-sugars and dinucleotide enzymes. These substrates are metabolites or cell signaling molecules that require regulation during different stages of the cell cycle or during periods of stress. In general, the role of the nudix hydrolase is to sanitize the nucleotide pools and to maintain cell viability, thereby serving as surveillance and house- cleaning enzymes; NUDIX hydrolase 845483 9797006 AARI_07580 Arthrobacter arilaitensis Re117 NUDIX hydrolase YP_003915952.1 845016 D 861360 CDS YP_003915953.1 308176547 9797009 complement(846808..848220) 1 NC_014550.1 catalyzes the reversible hydration of fumarate to L- malate. Involved in the TCA cycle; fumarate hydratase class II 848220 fumC 9797009 fumC Arthrobacter arilaitensis Re117 fumarate hydratase class II YP_003915953.1 846808 R 861360 CDS YP_003915954.1 308176548 9793872 complement(848351..848980) 1 NC_014550.1 carbonate dehydratases are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide. They are ubiquitous enzymes involved in fundamental processes like respiration, pH homeostasis and ion transport; carbonate dehydratase 848980 9793872 AARI_07620 Arthrobacter arilaitensis Re117 carbonate dehydratase YP_003915954.1 848351 R 861360 CDS YP_003915955.1 308176549 9797010 849072..849488 1 NC_014550.1 hypothetical protein 849488 9797010 AARI_07630 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915955.1 849072 D 861360 CDS YP_003915956.1 308176550 9793406 complement(850571..851245) 1 NC_014550.1 1 transmembrane helice predicted by TMHMM2.0; hypothetical protein 851245 9793406 AARI_07640 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915956.1 850571 R 861360 CDS YP_003915957.1 308176551 9797012 851402..852436 1 NC_014550.1 catalyzes the hydrolysis of fructose 1,6- bisphosphate to fructose 6-phosphate. Involved in gluconeogenesis; fructose-bisphosphatase, class II 852436 glpX 9797012 glpX Arthrobacter arilaitensis Re117 fructose-bisphosphatase, class II YP_003915957.1 851402 D 861360 CDS YP_003915958.1 308176552 9793915 complement(852541..853749) 1 NC_014550.1 catalyzes the interconversion of mannose-6- phosphate and fructose-6-phosphate. In prokaryotes, it is involved in a variety of pathways including capsular polysaccharide biosynthesis and D-mannose metabolism; class I mannose-6-phosphate isomerase 853749 manA 9793915 manA Arthrobacter arilaitensis Re117 class I mannose-6-phosphate isomerase YP_003915958.1 852541 R 861360 CDS YP_003915959.1 308176553 9794055 complement(853817..855424) 1 NC_014550.1 cell envelope-related transcriptional attenuator 855424 9794055 AARI_07670 Arthrobacter arilaitensis Re117 cell envelope-related transcriptional attenuator YP_003915959.1 853817 R 861360 CDS YP_003915960.1 308176554 9797013 complement(855442..855972) 1 NC_014550.1 phosphoribosylaminoimidazole carboxylase catalyses the sixth step of de novo purine biosynthesis, the decarboxylation of 1-(5-phosphoribosyl)-5-amino-4- imidazole-carboxylate (AIR); phosphoribosylaminoimidazole carboxylase catalytic subunit 855972 purE 9797013 purE Arthrobacter arilaitensis Re117 phosphoribosylaminoimidazole carboxylase catalytic subunit YP_003915960.1 855442 R 861360 CDS YP_003915961.1 308176555 9794248 complement(856046..857158) 1 NC_014550.1 phosphoribosylaminoimidazole carboxylase catalyses the sixth step of de novo purine biosynthesis, the decarboxylation of 1-(5-phosphoribosyl)-5-amino-4- imidazole-carboxylate (AIR); phosphoribosylaminoimidazole carboxylase ATPase subunit 857158 purK 9794248 purK Arthrobacter arilaitensis Re117 phosphoribosylaminoimidazole carboxylase ATPase subunit YP_003915961.1 856046 R 861360 CDS YP_003915962.1 308176556 9794251 857383..857952 1 NC_014550.1 identified by match to protein family PF04138. Members of this family are predicted to be integral membrane proteins with three or four transmembrane spans. They are involved in the synthesis of cell surface polysaccharides; GtrA-like protein 857952 9794251 AARI_07700 Arthrobacter arilaitensis Re117 GtrA-like protein YP_003915962.1 857383 D 861360 CDS YP_003915963.1 308176557 9797014 complement(857949..858677) 1 NC_014550.1 hypothetical protein 858677 9797014 AARI_07710 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915963.1 857949 R 861360 CDS YP_003915964.1 308176558 9797015 858976..859500 1 NC_014550.1 identified by match to protein family PF02467. WhiB is a transcription factor in Actinobacteria, required for differentiation and sporulation; WhiB family transcriptional regulator 859500 9797015 AARI_07720 Arthrobacter arilaitensis Re117 WhiB family transcriptional regulator YP_003915964.1 858976 D 861360 CDS YP_003915965.1 308176559 9797016 859569..862970 1 NC_014550.1 match to PF00535: glycosyl transferase family 2. This domain is found in a diverse family of glycosyl transferases that transfer the sugar from UDP-glucose, UDP- N-acetyl-galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids; glycosyl transferase family 2 862970 9797016 AARI_07730 Arthrobacter arilaitensis Re117 glycosyl transferase family 2 YP_003915965.1 859569 D 861360 CDS YP_003915966.1 308176560 9797017 862970..865567 1 NC_014550.1 1 transmembrane helice predicted by TMHMM2.0; hypothetical protein 865567 9797017 AARI_07740 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915966.1 862970 D 861360 CDS YP_003915967.1 308176561 9797018 865594..866523 1 NC_014550.1 identified by match to protein family PF02628. One member of this family, CtaA, is required for cytochrome aa3 biosynthesis in Bacillus subtilis; cytochrome oxidase assembly protein 866523 9797018 AARI_07750 Arthrobacter arilaitensis Re117 cytochrome oxidase assembly protein YP_003915967.1 865594 D 861360 CDS YP_003915968.1 308176562 9797019 complement(866536..866994) 1 NC_014550.1 hypothetical protein 866994 9797019 AARI_07760 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915968.1 866536 R 861360 CDS YP_003915969.1 308176563 9797020 867027..867254 1 NC_014550.1 hypothetical protein 867254 9797020 AARI_07770 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915969.1 867027 D 861360 CDS YP_003915970.1 308176564 9797021 867251..867487 1 NC_014550.1 hypothetical protein 867487 9797021 AARI_07780 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915970.1 867251 D 861360 CDS YP_003915971.1 308176565 9797022 867698..869299 1 NC_014550.1 4 transmembrane helices predicted by TMHMM2.0; hypothetical protein 869299 9797022 AARI_07790 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915971.1 867698 D 861360 CDS YP_003915972.1 308176566 9797023 complement(869369..871210) 1 NC_014550.1 activates fatty acids by binding to coenzyme A. Possibly involved in the synthesis of cellular lipids or their degradation via beta-oxidation; fatty-acid--CoA ligase 871210 9797023 AARI_07800 Arthrobacter arilaitensis Re117 fatty-acid--CoA ligase YP_003915972.1 869369 R 861360 CDS YP_003915973.1 308176567 9797024 complement(871289..872899) 1 NC_014550.1 identified by match to protein family PF02366. Transfers mannosyl residues to the hydroxy of serine or threonine residues, producing cell-wall mannoproteins; dolichyl-phosphate-mannose-protein mannosyltransferase 872899 9797024 AARI_07810 Arthrobacter arilaitensis Re117 dolichyl-phosphate-mannose-protein mannosyltransferase YP_003915973.1 871289 R 861360 CDS YP_003915974.1 308176568 9797025 872968..873828 1 NC_014550.1 tetrapyrrole methylase 873828 9797025 AARI_07820 Arthrobacter arilaitensis Re117 tetrapyrrole methylase YP_003915974.1 872968 D 861360 CDS YP_003915975.1 308176569 9797026 873967..875454 1 NC_014550.1 succinate-semialdehyde dehydrogenase (NAD(P)(+)) reduces succinate semialdehyde into succinate. Involved in the degradation of gamma-aminobutyrate; succinate-semialdehyde dehydrogenase 875454 gabD 9797026 gabD Arthrobacter arilaitensis Re117 succinate-semialdehyde dehydrogenase YP_003915975.1 873967 D 861360 CDS YP_003915976.1 308176570 9793875 complement(875523..877940) 1 NC_014550.1 identified by match to protein domain PF01841: Transglutaminase-like superfamily. Most microbial homologues of the transglutaminases are probably proteases. 8 transmembrane helices predicted by TMHMM2.0; transglutaminase 877940 9793875 AARI_07840 Arthrobacter arilaitensis Re117 transglutaminase YP_003915976.1 875523 R 861360 CDS YP_003915977.1 308176571 9797027 complement(877930..879255) 1 NC_014550.1 hypothetical protein 879255 9797027 AARI_07850 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915977.1 877930 R 861360 CDS YP_003915978.1 308176572 9797028 complement(879266..880228) 1 NC_014550.1 identified by match to protein family PIRSF002849. AAA family proteins often perform chaperone-like functions that assist in the assembly, operation, or disassembly of protein complexes; AAA-type ATPase enzymatic complex assembly chaperone 880228 9797028 AARI_07860 Arthrobacter arilaitensis Re117 AAA-type ATPase enzymatic complex assembly chaperone YP_003915978.1 879266 R 861360 CDS YP_003915979.1 308176573 9797029 880437..881393 1 NC_014550.1 identified by match to protein family PF01026; TatD-related deoxyribonuclease 881393 9797029 AARI_07870 Arthrobacter arilaitensis Re117 TatD-related deoxyribonuclease YP_003915979.1 880437 D 861360 CDS YP_003915980.1 308176574 9797030 881652..882815 1 NC_014550.1 match to protein domains PF03990 (DUF348 domain of unknown function), PF07501 (G5 domain) and PF06737 (transglycosylase-like domain). The PF07501 domain is also found in proteins involved in metabolism of bacterial cell walls suggesting this domain may have an adhesive function; cell wall function protein 882815 9797030 AARI_07880 Arthrobacter arilaitensis Re117 cell wall function protein YP_003915980.1 881652 D 861360 CDS YP_003915981.1 308176575 9797031 882913..883800 1 NC_014550.1 specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3 prime-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance; dimethyladenosine transferase 883800 ksgA 9797031 ksgA Arthrobacter arilaitensis Re117 dimethyladenosine transferase YP_003915981.1 882913 D 861360 CDS YP_003915982.1 308176576 9794025 883803..884735 1 NC_014550.1 forms part of the non-mevalonate pathway for terpenoid biosynthesis; 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase 884735 ispE 9794025 ispE Arthrobacter arilaitensis Re117 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase YP_003915982.1 883803 D 861360 CDS YP_003915983.1 308176577 9794012 884890..886260 1 NC_014550.1 FAD-dependent oxidoreductase 886260 9794012 AARI_07910 Arthrobacter arilaitensis Re117 FAD-dependent oxidoreductase YP_003915983.1 884890 D 861360 CDS YP_003915984.1 308176578 9797032 886292..886471 1 NC_014550.1 hypothetical protein 886471 9797032 AARI_07920 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915984.1 886292 D 861360 CDS YP_003915985.1 308176579 9797033 886464..886988 1 NC_014550.1 identified by match to PF00583: acetyltransferase (GNAT) family; GNAT family acetyltransferase 886988 9797033 AARI_07930 Arthrobacter arilaitensis Re117 GNAT family acetyltransferase YP_003915985.1 886464 D 861360 CDS YP_003915986.1 308176580 9797034 complement(886975..887253) 1 NC_014550.1 hypothetical protein 887253 9797034 AARI_07940 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915986.1 886975 R 861360 CDS YP_003915987.1 308176581 9797035 complement(887363..889153) 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, () drug resistance ATPase-2 (Drug RA2) family (TC 3.A.1.121.z). ABCISSE: fused ATP-binding protein (ABC2), ART-family, ARE-subfamily (antibiotic resistance); drug resistance ATP-binding protein 889153 9797035 AARI_07950 Arthrobacter arilaitensis Re117 drug resistance ATP-binding protein YP_003915987.1 887363 R 861360 CDS YP_003915988.1 308176582 9793601 889558..891009 1 NC_014550.1 glucosamine-1-phosphate N-acetyltransferase (EC 2.3. 1.157) and UDP-N-acetylglucosamine diphosphorylase (EC 2.7. 7.23) perform the last two steps in the synthesis of UDP-N-acetylglucosamine, which is an essential precursor in both the peptidoglycan and the lipopolysaccharide metabolic pathway; bifunctional UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase 891009 glmU 9793601 glmU Arthrobacter arilaitensis Re117 bifunctional UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase YP_003915988.1 889558 D 861360 CDS YP_003915989.1 308176583 9793905 891082..892062 1 NC_014550.1 catalyzes the formation of PRPP from ATP and ribose 5-phosphate. PRPP is then used in various biosynthetic pathways, as for example in the formation of purines, pyrimidines, histidine and tryptophan; ribose-phosphate diphosphokinase 892062 prs 9793905 prs Arthrobacter arilaitensis Re117 ribose-phosphate diphosphokinase YP_003915989.1 891082 D 861360 CDS YP_003915990.1 308176584 9794234 892820..893566 1 NC_014550.1 hypothetical protein 893566 9794234 AARI_07980 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915990.1 892820 D 861360 CDS YP_003915991.1 308176585 9793407 complement(894921..895337) 1 NC_014550.1 hypothetical protein 895337 9793407 AARI_07990 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915991.1 894921 R 861360 CDS YP_003915992.1 308176586 9797038 895598..896905 1 NC_014550.1 transposase of ISAar19, ISL3 family 896905 9797038 AARI_34640 Arthrobacter arilaitensis Re117 transposase of ISAar19, ISL3 family YP_003915992.1 895598 D 861360 CDS YP_003915993.1 308176587 9793408 complement(897229..900018) 1 NC_014550.1 signal peptide predicted by SignalP 3.0 HMM (probability: 1.000) with cleavage site probability 0.575 between position 36 and 37. 7 transmembrane helices predicted by TMHMM2.0 after the signal peptide; hypothetical protein 900018 9793408 AARI_08000 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915993.1 897229 R 861360 CDS YP_003915994.1 308176588 9797039 complement(900015..900635) 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, lipoprotein translocase (LPT) family (TC 3.A.1.125.z). ABCISSE: ABC transporter, ATP-binding protein (ABC), o228 family (members of this family might be involved in a more general lipoprotein releasing mechanism common to all prokaryotes); ABC transporter ATP-binding subunit 900635 9797039 AARI_08010 Arthrobacter arilaitensis Re117 ABC transporter ATP-binding subunit YP_003915994.1 900015 R 861360 CDS YP_003915995.1 308176589 9797040 complement(901049..901534) 1 NC_014550.1 hypothetical protein 901534 9797040 AARI_08020 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915995.1 901049 R 861360 CDS YP_003915996.1 308176590 9797042 902168..902446 1 NC_014550.1 transposase of ISAar3, IS3 family, IS407 group, orfA 902446 9797042 AARI_34650 Arthrobacter arilaitensis Re117 transposase of ISAar3, IS3 family, IS407 group, orfA YP_003915996.1 902168 D 861360 CDS YP_003915997.1 308176591 9793409 902476..903315 1 NC_014550.1 transposase of ISAar3, IS3 family, IS407 group, orfB 903315 9793409 AARI_34660 Arthrobacter arilaitensis Re117 transposase of ISAar3, IS3 family, IS407 group, orfB YP_003915997.1 902476 D 861360 CDS YP_003915998.1 308176592 9793410 complement(903909..904241) 1 NC_014550.1 hypothetical protein 904241 9793410 AARI_08040 Arthrobacter arilaitensis Re117 hypothetical protein YP_003915998.1 903909 R 861360 CDS YP_003915999.1 308176593 9797043 complement(904238..904969) 1 NC_014550.1 helper of transposition of ISAar7, IS21 family, istB 904969 istB 9797043 istB Arthrobacter arilaitensis Re117 helper of transposition of ISAar7, IS21 family, istB YP_003915999.1 904238 R 861360 CDS YP_003916000.1 308176594 9794019 complement(904966..906429) 1 NC_014550.1 transposase of ISAar7, IS21 family, istA 906429 istA 9794019 istA Arthrobacter arilaitensis Re117 transposase of ISAar7, IS21 family, istA YP_003916000.1 904966 R 861360 CDS YP_003916001.1 308176595 9797044 907397..908152 1 NC_014550.1 signal peptide predicted by SignalP 3.0 HMM (probability: 1) with cleavage site probability 0.973 between position 26 and 27; hypothetical protein 908152 9797044 AARI_08060 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916001.1 907397 D 861360 CDS YP_003916002.1 308176596 9797045 908235..909416 1 NC_014550.1 signal peptide predicted by SignalP 3.0 HMM (probability: 1) with cleavage site probability 0.751 between position 32 and 33; hypothetical protein 909416 9797045 AARI_08070 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916002.1 908235 D 861360 CDS YP_003916003.1 308176597 9797046 complement(909820..911127) 1 NC_014550.1 transposase of ISAar20, ISL3 family 911127 9797046 AARI_34690 Arthrobacter arilaitensis Re117 transposase of ISAar20, ISL3 family YP_003916003.1 909820 R 861360 CDS YP_003916004.1 308176598 9793411 complement(912376..913653) 1 NC_014550.1 transposase of ISAar13, ISL3 family 913653 9793411 AARI_34700 Arthrobacter arilaitensis Re117 transposase of ISAar13, ISL3 family YP_003916004.1 912376 R 861360 CDS YP_003916005.1 308176599 9793412 complement(913958..914374) 1 NC_014550.1 hypothetical protein 914374 9793412 AARI_08080 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916005.1 913958 R 861360 CDS YP_003916006.1 308176600 9797047 complement(914521..915093) 1 NC_014550.1 match to PF00239. Possibly involved in site- specific recombination of DNA; resolvase 915093 9797047 AARI_08090 Arthrobacter arilaitensis Re117 resolvase YP_003916006.1 914521 R 861360 CDS YP_003916007.1 308176601 9797048 915253..915783 1 NC_014550.1 hypothetical protein 915783 9797048 AARI_08100 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916007.1 915253 D 861360 CDS YP_003916008.1 308176602 9797049 915999..916283 1 NC_014550.1 part of the 50S ribosomal subunit. Contacts the 5S rRNA; 50S ribosomal protein L25 916283 rplY 9797049 rplY Arthrobacter arilaitensis Re117 50S ribosomal protein L25 YP_003916008.1 915999 D 861360 CDS YP_003916009.1 308176603 9794332 916314..916895 1 NC_014550.1 cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through abortion of translation and is essential for cell viability; peptidyl-tRNA hydrolase 916895 pth 9794332 pth Arthrobacter arilaitensis Re117 peptidyl-tRNA hydrolase YP_003916009.1 916314 D 861360 CDS YP_003916010.1 308176604 9794240 917153..918445 1 NC_014550.1 cysteine desulfurase catalyses the following reaction: L-cysteine + [enzyme]-cysteine <=> L-alanine + [enzyme]-S-sulfanylcysteine. It is involved in the biosynthesis of iron-sulfur clusters, thio-nucleosides in tRNA, thiamine, biotin, lipoate and pyranopterin (molybdopterin) and functions by mobilizing sulfur; cysteine desulfurase 918445 sufS 9794240 sufS Arthrobacter arilaitensis Re117 cysteine desulfurase YP_003916010.1 917153 D 861360 CDS YP_003916011.1 308176605 9794416 918446..918898 1 NC_014550.1 identified by match to protein family TIGR01994. The SUF system is an iron-sulfur cluster assembly system that operates under iron starvation and oxidative stress. SufU may act as a scaffold on which the Fe-S cluster is built and from which it is transferred; SUF system FeS assembly protein 918898 sufU 9794416 sufU Arthrobacter arilaitensis Re117 SUF system FeS assembly protein YP_003916011.1 918446 D 861360 CDS YP_003916012.1 308176606 9794417 complement(918977..920260) 1 NC_014550.1 NhaA Na+:H+antiporter (NhaA) family (TC 2.A.33.y.z). Na(+)/H(+) antiporter extrudes sodium in exchange for external protons. Active at alkaline pH. In E. coli, NhaA protein probably functions in the regulation of the internal pH when the external pH is alkaline. It also uses the H+ gradient to expel Na+ from the cell. Its activity is highly pH dependent; Na+/H+ antiporter NhaA 920260 nhaA 9794417 nhaA Arthrobacter arilaitensis Re117 Na+/H+ antiporter NhaA YP_003916012.1 918977 R 861360 CDS YP_003916013.1 308176607 9794139 complement(920498..920992) 1 NC_014550.1 hypothetical protein 920992 9794139 AARI_08160 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916013.1 920498 R 861360 CDS YP_003916014.1 308176608 9797050 921238..924852 1 NC_014550.1 necessary for strand-specific repair. A lesion in the template strand blocks the RNA polymerase complex (RNAP). The RNAP-DNA-RNA complex is specifically recognized by TRCF which releases RNAP and the truncated transcript; the TCRF may replace RNAP at the lesion site and then recruit the uvrA/B/C repair system; transcription-repair-coupling factor 924852 mfd 9797050 mfd Arthrobacter arilaitensis Re117 transcription-repair-coupling factor YP_003916014.1 921238 D 861360 CDS YP_003916015.1 308176609 9794080 complement(925175..925582) 1 NC_014550.1 3 transmembrane helices predicted by TMHMM2.0; hypothetical protein 925582 9794080 AARI_08180 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916015.1 925175 R 861360 CDS YP_003916016.1 308176610 9797051 complement(925774..926274) 1 NC_014550.1 hypothetical protein 926274 9797051 AARI_08190 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916016.1 925774 R 861360 CDS YP_003916017.1 308176611 9797052 complement(926276..928174) 1 NC_014550.1 TCDB: P-type ATPase (P-ATPase) superfamily (TC 3.A. 3.y.z). Involved in export of cations; cation-transporting ATPase 928174 9797052 AARI_08200 Arthrobacter arilaitensis Re117 cation-transporting ATPase YP_003916017.1 926276 R 861360 CDS YP_003916018.1 308176612 9797053 complement(928320..928487) 1 NC_014550.1 hypothetical protein 928487 9797053 AARI_08210 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916018.1 928320 R 861360 CDS YP_003916019.1 308176613 9797054 complement(928702..928959) 1 NC_014550.1 hypothetical protein 928959 9797054 AARI_08220 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916019.1 928702 R 861360 CDS YP_003916020.1 308176614 9797055 complement(928995..929681) 1 NC_014550.1 catalyzes a reversible aldol reaction between acetaldehyde and glyceraldehyde 3-phosphate to generate 2- deoxyribose 5-phosphate; deoxyribose-phosphate aldolase 929681 deoC 9797055 deoC Arthrobacter arilaitensis Re117 deoxyribose-phosphate aldolase YP_003916020.1 928995 R 861360 CDS YP_003916021.1 308176615 9793803 complement(929741..931471) 1 NC_014550.1 this family is composed of four related enzymes, each of which catalyses a phosphoryl transfer on their sugar substrates: phosphoglucomutase (PGM), hosphoglucomutase/phosphomannomutase (PGM/PMM), phosphoglucosamine mutase (PNGM), and phosphoacetylglucosamine mutase (PAGM). PGM (EC:5.4.2.2) converts D-glucose 1-phosphate into D-glucose 6-phosphate, and participates in both the breakdown and synthesis of glucose. PGM/PMM (EC:5.4.2.2; EC:5.4.2.8) are primarily bacterial enzymes that use either glucose or mannose as substrate, participating in the biosynthesis of a variety of carbohydrates such as lipopolysaccharides and alginate. Both PNGM (EC:5.4.2.3) and PAGM (EC:5.4.2.10) are involved in the biosynthesis of UDP-N-acetylglucosamine; alpha-D-phosphohexomutase family protein 931471 9793803 AARI_08240 Arthrobacter arilaitensis Re117 alpha-D-phosphohexomutase family protein YP_003916021.1 929741 R 861360 CDS YP_003916022.1 308176616 9797056 complement(931525..932334) 1 NC_014550.1 catalyzes the cleavage of guanosine, deoxyguanosine, inosine, deoxyinosine, adenosine or deoxyadenosine to respective bases and sugar-1-phosphate molecules; purine-nucleoside phosphorylase 932334 deoD 9797056 deoD Arthrobacter arilaitensis Re117 purine-nucleoside phosphorylase YP_003916022.1 931525 R 861360 CDS YP_003916023.1 308176617 9793804 932452..933861 1 NC_014550.1 E3 component of pyruvate dehydrogenase and 2- oxoglutarate dehydrogenase complexes; dihydrolipoyl dehydrogenase 933861 lpdA 9793804 lpdA Arthrobacter arilaitensis Re117 dihydrolipoyl dehydrogenase YP_003916023.1 932452 D 861360 CDS YP_003916024.1 308176618 9794042 complement(934010..935209) 1 NC_014550.1 transposase of ISAar5, IS256 family 935209 9794042 AARI_34710 Arthrobacter arilaitensis Re117 transposase of ISAar5, IS256 family YP_003916024.1 934010 R 861360 CDS YP_003916025.1 308176619 9793413 935545..936933 1 NC_014550.1 major facilitator superfamily (MFS), metabolite:H+ symporter (MHS) family (TC 2.A.1.6.z); MFS superfamily transporter 936933 9793413 AARI_08270 Arthrobacter arilaitensis Re117 MFS superfamily transporter YP_003916025.1 935545 D 861360 CDS YP_003916026.1 308176620 9797059 938047..938415 1 NC_014550.1 hypothetical protein 938415 9797059 AARI_08300 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916026.1 938047 D 861360 CDS YP_003916027.1 308176621 9797060 complement(938487..940271) 1 NC_014550.1 enzymes named acetyl-coenzyme A carboxylase (EC 6.4. 1.2), propionyl-coenzyme A carboxylase (EC 6.4.1.3) and acyl-coenzyme A carboxylase are constituted by several types of subunits. Alpha subunits contains the biotin carboxylase (BC, EC 6.3.4.14) and biotin carboxyl carrier protein (BCCP) domains, beta subunits contain the carboxyltransferase (CT) domain. An epsilon subunit is present in some microorganisms; acetyl-/propionyl-coenzyme A carboxylase subunit alpha 940271 9797060 AARI_08310 Arthrobacter arilaitensis Re117 acetyl-/propionyl-coenzyme A carboxylase subunit alpha YP_003916027.1 938487 R 861360 CDS YP_003916028.1 308176622 9797061 complement(940490..941686) 1 NC_014550.1 transposase of ISAar2, IS110 family 941686 9797061 AARI_34720 Arthrobacter arilaitensis Re117 transposase of ISAar2, IS110 family YP_003916028.1 940490 R 861360 CDS YP_003916029.1 308176623 9793414 942018..942377 1 NC_014550.1 signal peptide predicted by SignalP 3.0 HMM (probability: 0.973) with cleavage site probability 0.445 between position 32 and 33; hypothetical protein 942377 9793414 AARI_08320 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916029.1 942018 D 861360 CDS YP_003916030.1 308176624 9797062 complement(942651..943139) 1 NC_014550.1 hypothetical protein 943139 9797062 AARI_08330 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916030.1 942651 R 861360 CDS YP_003916031.1 308176625 9797063 943195..943398 1 NC_014550.1 hypothetical protein 943398 9797063 AARI_08340 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916031.1 943195 D 861360 CDS YP_003916032.1 308176626 9797064 complement(943454..944095) 1 NC_014550.1 match to PF02545. Maf is a inhibitor of septum formation in eukaryotes, bacteria, and archaea; Maf-like protein 944095 9797064 AARI_08350 Arthrobacter arilaitensis Re117 Maf-like protein YP_003916032.1 943454 R 861360 CDS YP_003916033.1 308176627 9797065 complement(944092..947595) 1 NC_014550.1 Resistance-Nodulation-Cell Division (RND) superfamily (TC 2.A.6.y.z). C-terminal part of the protein: PS50156 domain (sterol-sensing domain). In bacteria, this domain is found in a number of drug resistance protein; drug exporter of the RND superfamily 947595 9797065 AARI_08360 Arthrobacter arilaitensis Re117 drug exporter of the RND superfamily YP_003916033.1 944092 R 861360 CDS YP_003916034.1 308176628 9797066 complement(947600..948271) 1 NC_014550.1 match to PF00440: bacterial regulatory proteins, tetR family; transcriptional regulator 948271 9797066 AARI_08370 Arthrobacter arilaitensis Re117 transcriptional regulator YP_003916034.1 947600 R 861360 CDS YP_003916035.1 308176629 9797067 complement(948417..949772) 1 NC_014550.1 transposase of ISAar28, IS481 family 949772 9797067 AARI_34730 Arthrobacter arilaitensis Re117 transposase of ISAar28, IS481 family YP_003916035.1 948417 R 861360 CDS YP_003916036.1 308176630 9797068 950999..952306 1 NC_014550.1 transposase of ISAar19, ISL3 family 952306 9797068 AARI_34740 Arthrobacter arilaitensis Re117 transposase of ISAar19, ISL3 family YP_003916036.1 950999 D 861360 CDS YP_003916037.1 308176631 9797069 complement(953085..953531) 1 NC_014550.1 signal peptide predicted by SignalP 3.0 HMM (probability: 0.890) with cleavage site probability 0.644 between position 24 and 25. 3 transmembrane helices predicted by TMHMM2.0 after the signal peptide; hypothetical protein 953531 9797069 AARI_08400 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916037.1 953085 R 861360 CDS YP_003916038.1 308176632 9797070 953784..954440 1 NC_014550.1 hypothetical protein 954440 9797070 AARI_08410 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916038.1 953784 D 861360 CDS YP_003916039.1 308176633 9797071 954559..954942 1 NC_014550.1 3 transmembrane helices predicted by TMHMM2.0; hypothetical protein 954942 9797071 AARI_08420 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916039.1 954559 D 861360 CDS YP_003916040.1 308176634 9797072 955060..955449 1 NC_014550.1 identified by match to PF00903: glyoxalase/bleomycin resistance protein/dioxygenase superfamily; glyoxalase family protein 955449 9797072 AARI_08430 Arthrobacter arilaitensis Re117 glyoxalase family protein YP_003916040.1 955060 D 861360 CDS YP_003916041.1 308176635 9797073 complement(955505..957172) 1 NC_014550.1 hypothetical protein 957172 9797073 AARI_08440 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916041.1 955505 R 861360 CDS YP_003916042.1 308176636 9797074 957522..963725 1 NC_014550.1 1 transmembrane helice predicted by TMHMM2.0; hypothetical protein 963725 9797074 AARI_08450 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916042.1 957522 D 861360 CDS YP_003916043.1 308176637 9797075 963778..964788 1 NC_014550.1 identified by match to protein family PIRSF002849. AAA family proteins often perform chaperone-like functions that assist in the assembly, operation, or disassembly of protein complexes; AAA-type ATPase enzymatic complex assembly chaperone 964788 9797075 AARI_08460 Arthrobacter arilaitensis Re117 AAA-type ATPase enzymatic complex assembly chaperone YP_003916043.1 963778 D 861360 CDS YP_003916044.1 308176638 9797076 964788..966107 1 NC_014550.1 2 transmembrane helices predicted by TMHMM2.0; hypothetical protein 966107 9797076 AARI_08470 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916044.1 964788 D 861360 CDS YP_003916045.1 308176639 9797079 968460..969542 1 NC_014550.1 match to PF06271. The molecular function of this region is unknown. However it be involved in transport of an as yet unknown set of ligands; RDD domain-containing protein 969542 9797079 AARI_08500 Arthrobacter arilaitensis Re117 RDD domain-containing protein YP_003916045.1 968460 D 861360 CDS YP_003916046.1 308176640 9797080 969539..970366 1 NC_014550.1 match to PF00481: protein phosphatase 2C; protein phosphatase domain-containing protein 970366 9797080 AARI_08510 Arthrobacter arilaitensis Re117 protein phosphatase domain-containing protein YP_003916046.1 969539 D 861360 CDS YP_003916047.1 308176641 9797081 970363..972156 1 NC_014550.1 match to PF00498. The forkhead-associated (FHA) domain is a phosphopeptide recognition domain found in many regulatory proteins; FHA domain-containing protein 972156 9797081 AARI_08520 Arthrobacter arilaitensis Re117 FHA domain-containing protein YP_003916047.1 970363 D 861360 CDS YP_003916048.1 308176642 9795167 972153..973712 1 NC_014550.1 identified by match to protein domain PD000001. Match to PS00108 pattern. Protein kinases are a group of enzymes that possess a catalytic subunit which transfers the gamma phosphate from nucleotide triphosphates (often ATP) to one or more amino acid residues in a protein substrate side chain, resulting in a conformational change affecting protein function. They play a role in a mulititude of cellular processes, including division, proliferation, apoptosis, and differentiation; Ser/Thr protein kinase 973712 9795167 AARI_08530 Arthrobacter arilaitensis Re117 Ser/Thr protein kinase YP_003916048.1 972153 D 861360 CDS YP_003916049.1 308176643 9795168 973722..974423 1 NC_014550.1 hypothetical protein 974423 9795168 AARI_08540 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916049.1 973722 D 861360 CDS YP_003916050.1 308176644 9795169 complement(974509..974727) 1 NC_014550.1 identified by similarity to protein SP: P96886 (Mycobacterium tuberculosis). Enzymes named acetyl- coenzyme A carboxylase (EC 6.4.1.2), propionyl-coenzyme A carboxylase (EC 6.4.1.3) and acyl-coenzyme A carboxylase are constituted by several types of subunits. Alpha subunits contains the biotin carboxylase (BC, EC 6.3.4.14) and biotin carboxyl carrier protein (BCCP) domains, beta subunits contain the carboxyltransferase (CT) domain. An epsilon subunit is present in some microorganisms; acetyl-/propionyl-coenzyme A carboxylase subunit epsilon 974727 9795169 AARI_08550 Arthrobacter arilaitensis Re117 acetyl-/propionyl-coenzyme A carboxylase subunit epsilon YP_003916050.1 974509 R 861360 CDS YP_003916051.1 308176645 9795170 complement(974777..976387) 1 NC_014550.1 enzymes named acetyl-coenzyme A carboxylase (EC 6.4. 1.2), propionyl-coenzyme A carboxylase (EC 6.4.1.3) and acyl-coenzyme A carboxylase are constituted by several types of subunits. Alpha subunits contains the biotin carboxylase (BC, EC 6.3.4.14) and biotin carboxyl carrier protein (BCCP) domains, beta subunits contain the carboxyltransferase (CT) domain. An epsilon subunit is present in some microorganisms; acetyl-/propionyl-coenzyme A carboxylase subunit beta 976387 9795170 AARI_08560 Arthrobacter arilaitensis Re117 acetyl-/propionyl-coenzyme A carboxylase subunit beta YP_003916051.1 974777 R 861360 CDS YP_003916052.1 308176646 9795171 976584..977441 1 NC_014550.1 identified by match to PF00106. The short-chain dehydrogenases/reductases family (SDR) is a very large family of enzymes, most of which are known to be NAD- or NADP-dependent oxidoreductases; short-chain dehydrogenases/reductase 977441 9795171 AARI_08570 Arthrobacter arilaitensis Re117 short-chain dehydrogenases/reductase YP_003916052.1 976584 D 861360 CDS YP_003916053.1 308176647 9795172 977498..978364 1 NC_014550.1 acts both as a biotin-operon repressor and as the enzyme that synthesizes the corepressor, acetyl-CoA:carbon- dioxide ligase. This protein also activates biotin to form biotinyl-5-adenylate and transfers the biotin moiety to biotin-accepting proteins; biotin-(acetyl-CoA carboxylase) ligase 978364 birA 9795172 birA Arthrobacter arilaitensis Re117 biotin-(acetyl-CoA carboxylase) ligase YP_003916053.1 977498 D 861360 CDS YP_003916054.1 308176648 9793720 978451..978999 1 NC_014550.1 2 transmembrane helices predicted by TMHMM2.0; hypothetical protein 978999 9793720 AARI_08590 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916054.1 978451 D 861360 CDS YP_003916055.1 308176649 9795173 978996..980207 1 NC_014550.1 identified by similarity to protein SP:P27580 (Arthrobacter nicotianae). Plays essential roles in regulation of cellular metabolism by catalyzing the synthesis of a second messenger, cAMP; adenylate cyclase 980207 cya 9795173 cya Arthrobacter arilaitensis Re117 adenylate cyclase YP_003916055.1 978996 D 861360 CDS YP_003916056.1 308176650 9793768 980207..981163 1 NC_014550.1 match to PF00481: protein phosphatase 2C; protein phosphatase domain-containing protein 981163 9793768 AARI_08610 Arthrobacter arilaitensis Re117 protein phosphatase domain-containing protein YP_003916056.1 980207 D 861360 CDS YP_003916057.1 308176651 9795174 981184..983487 1 NC_014550.1 catalyzes the formation of phosphodiester linkages between 5 prime-phosphoryl and 3 prime-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; DNA ligase 983487 ligA 9795174 ligA Arthrobacter arilaitensis Re117 DNA ligase YP_003916057.1 981184 D 861360 CDS YP_003916058.1 308176652 9794038 983490..984290 1 NC_014550.1 catalyzes the following reaction: myo-inositol phosphate + H(2)O <=> myo-inositol + phosphate. Acts on five of the six isomers of myo-inositol phosphate, all except myo-inositol 2-phosphate, but does not act on myo- inositol bearing more than one phosphate group; inositol-phosphate phosphatase 984290 suhB 9794038 suhB Arthrobacter arilaitensis Re117 inositol-phosphate phosphatase YP_003916058.1 983490 D 861360 CDS YP_003916059.1 308176653 9794420 complement(984287..984898) 1 NC_014550.1 5 transmembrane helices predicted by TMHMM2.0; hypothetical protein 984898 9794420 AARI_08640 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916059.1 984287 R 861360 CDS YP_003916060.1 308176654 9795175 985105..985461 1 NC_014550.1 signal peptide predicted by SignalP 3.0 HMM (probability: 1.000) with cleavage site probability 0.959 between position 37 and 38; hypothetical protein 985461 9795175 AARI_08650 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916060.1 985105 D 861360 CDS YP_003916061.1 308176655 9795176 complement(985576..986025) 1 NC_014550.1 hypothetical protein 986025 9795176 AARI_08660 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916061.1 985576 R 861360 CDS YP_003916062.1 308176656 9795179 complement(986931..988061) 1 NC_014550.1 identified by match to PF00480: ROK family; transcriptional regulator 988061 9795179 AARI_08690 Arthrobacter arilaitensis Re117 transcriptional regulator YP_003916062.1 986931 R 861360 CDS YP_003916063.1 308176657 9795180 988273..988803 1 NC_014550.1 identified by match to PF00583: acetyltransferase (GNAT) family; GNAT family acetyltransferase 988803 9795180 AARI_08700 Arthrobacter arilaitensis Re117 GNAT family acetyltransferase YP_003916063.1 988273 D 861360 CDS YP_003916064.1 308176658 9795181 988895..990808 1 NC_014550.1 match to PF00905. The large number of penicillin binding proteins, which are represented in this group of sequences, are responsible for the final stages of peptidoglycan biosynthesis for cell wall formation. The proteins synthesise cross-linked peptidoglycan from lipid intermediates, and contain a penicillin-sensitive transpeptidase carboxy-terminal domain; penicillin-binding protein 990808 9795181 AARI_08710 Arthrobacter arilaitensis Re117 penicillin-binding protein YP_003916064.1 988895 D 861360 CDS YP_003916065.1 308176659 9795182 complement(990826..991425) 1 NC_014550.1 identified by match to PF00583: acetyltransferase (GNAT) family; GNAT family acetyltransferase 991425 9795182 AARI_08720 Arthrobacter arilaitensis Re117 GNAT family acetyltransferase YP_003916065.1 990826 R 861360 CDS YP_003916066.1 308176660 9795183 991511..992062 1 NC_014550.1 hypothetical protein 992062 9795183 AARI_08730 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916066.1 991511 D 861360 CDS YP_003916067.1 308176661 9795184 992147..992443 1 NC_014550.1 allows the formation of correctly charged Asn- tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; aspartyl/glutamyl-tRNA amidotransferase subunit C 992443 gatC 9795184 gatC Arthrobacter arilaitensis Re117 aspartyl/glutamyl-tRNA amidotransferase subunit C YP_003916067.1 992147 D 861360 CDS YP_003916068.1 308176662 9793888 992448..993986 1 NC_014550.1 allows the formation of correctly charged Asn- tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; aspartyl/glutamyl-tRNA amidotransferase subunit A 993986 gatA 9793888 gatA Arthrobacter arilaitensis Re117 aspartyl/glutamyl-tRNA amidotransferase subunit A YP_003916068.1 992448 D 861360 CDS YP_003916069.1 308176663 9793886 993992..995500 1 NC_014550.1 allows the formation of correctly charged Asn- tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; aspartyl/glutamyl-tRNA amidotransferase subunit B 995500 gatB 9793886 gatB Arthrobacter arilaitensis Re117 aspartyl/glutamyl-tRNA amidotransferase subunit B YP_003916069.1 993992 D 861360 CDS YP_003916070.1 308176664 9793887 complement(995715..995840) 1 NC_014550.1 hypothetical protein 995840 9793887 AARI_08770 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916070.1 995715 R 861360 CDS YP_003916071.1 308176665 9795185 complement(996223..996510) 1 NC_014550.1 2 transmembrane helices predicted by TMHMM2.0; hypothetical protein 996510 9795185 AARI_08780 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916071.1 996223 R 861360 CDS YP_003916072.1 308176666 9795186 complement(996588..997895) 1 NC_014550.1 transposase of ISAar19, ISL3 family 997895 9795186 AARI_34750 Arthrobacter arilaitensis Re117 transposase of ISAar19, ISL3 family YP_003916072.1 996588 R 861360 CDS YP_003916073.1 308176667 9795188 1000107..1001039 1 NC_014550.1 identified by match to PF01636. This family consists of bacterial antibiotic resistance proteins, which confer resistance to various aminoglycosides. It also includes homoserine kinase; aminoglycoside phosphotransferase-like protein 1001039 9795188 AARI_08810 Arthrobacter arilaitensis Re117 aminoglycoside phosphotransferase-like protein YP_003916073.1 1000107 D 861360 CDS YP_003916074.1 308176668 9795189 complement(1001461..1001805) 1 NC_014550.1 3 transmembrane helices predicted by TMHMM2.0; hypothetical protein 1001805 9795189 AARI_08820 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916074.1 1001461 R 861360 CDS YP_003916075.1 308176669 9795191 complement(1002483..1003184) 1 NC_014550.1 identified by match to protein family TIGR01509: HAD-superfamily hydrolase, subfamily IA, variant 3; match to protein family PF00702: haloacid dehalogenase-like hydrolase; hydrolase 1003184 9795191 AARI_08840 Arthrobacter arilaitensis Re117 hydrolase YP_003916075.1 1002483 R 861360 CDS YP_003916076.1 308176670 9795192 complement(1003192..1003638) 1 NC_014550.1 identified by match to protein family PF01047. Regulators with the marR-type HTH domain are present in bacteria and archaea and control a variety of biological functions, including resistance to multiple antibiotics, household disinfectants, organic solvents, oxidative stress agents and regulation of the virulence factor synthesis in pathogens of humans and plants. Many of the marR-like regulators respond to aromatic compounds; MarR family transcriptional regulator 1003638 9795192 AARI_08850 Arthrobacter arilaitensis Re117 MarR family transcriptional regulator YP_003916076.1 1003192 R 861360 CDS YP_003916077.1 308176671 9795193 1003753..1004895 1 NC_014550.1 major facilitator superfamily (TC 2.A.1.y.z). Identified by match to protein family PF07690 (Major Facilitator Superfamily); MFS superfamily transporter 1004895 9795193 AARI_08860 Arthrobacter arilaitensis Re117 MFS superfamily transporter YP_003916077.1 1003753 D 861360 CDS YP_003916078.1 308176672 9795194 1004940..1005770 1 NC_014550.1 catalyzes the reduction of 2,5-diketogluconic acid to 2-keto-L-gulonic acid, a key intermediate in the production of ascorbic acid. Can also reduce ethyl 2- methylacetoacetate stereoselectively to ethyl (2R)-methyl- (3S)-hydroxybutanoate and can also accept some other beta- keto esters. Identified by similarity to protein SP:Q46857 (Escherichia coli); 2,5-didehydrogluconate reductase 1005770 dkgA 9795194 dkgA Arthrobacter arilaitensis Re117 2,5-didehydrogluconate reductase YP_003916078.1 1004940 D 861360 CDS YP_003916079.1 308176673 9793817 complement(1006160..1006462) 1 NC_014550.1 hypothetical protein 1006462 9793817 AARI_08880 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916079.1 1006160 R 861360 CDS YP_003916080.1 308176674 9795195 complement(1006662..1007327) 1 NC_014550.1 hypothetical protein 1007327 9795195 AARI_08890 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916080.1 1006662 R 861360 CDS YP_003916081.1 308176675 9795196 complement(1007386..1007787) 1 NC_014550.1 hypothetical protein 1007787 9795196 AARI_08900 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916081.1 1007386 R 861360 CDS YP_003916082.1 308176676 9795197 complement(1008036..1008632) 1 NC_014550.1 identified by match to PF00583: acetyltransferase (GNAT) family; GNAT family acetyltransferase 1008632 9795197 AARI_08910 Arthrobacter arilaitensis Re117 GNAT family acetyltransferase YP_003916082.1 1008036 R 861360 CDS YP_003916083.1 308176677 9795198 1008779..1009531 1 NC_014550.1 match to PS00383 pattern (tyrosine specific protein phosphatases active site); hypothetical protein 1009531 9795198 AARI_08920 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916083.1 1008779 D 861360 CDS YP_003916084.1 308176678 9795199 complement(1009791..1010846) 1 NC_014550.1 major facilitator superfamily (TC 2.A.1.y.z). Identified by match to protein family PF07690 (Major Facilitator Superfamily); MFS superfamily transporter 1010846 9795199 AARI_08930 Arthrobacter arilaitensis Re117 MFS superfamily transporter YP_003916084.1 1009791 R 861360 CDS YP_003916085.1 308176679 9795200 complement(1011351..1011854) 1 NC_014550.1 identified by match to PF00583: acetyltransferase (GNAT) family; GNAT family acetyltransferase 1011854 9795200 AARI_08940 Arthrobacter arilaitensis Re117 GNAT family acetyltransferase YP_003916085.1 1011351 R 861360 CDS YP_003916086.1 308176680 9795201 complement(1011915..1012457) 1 NC_014550.1 hypothetical protein 1012457 9795201 AARI_08950 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916086.1 1011915 R 861360 CDS YP_003916087.1 308176681 9795202 complement(1012454..1012642) 1 NC_014550.1 hypothetical protein 1012642 9795202 AARI_08960 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916087.1 1012454 R 861360 CDS YP_003916088.1 308176682 9795203 1013023..1013586 1 NC_014550.1 identified by match to PF00583: acetyltransferase (GNAT) family; GNAT family acetyltransferase 1013586 9795203 AARI_08970 Arthrobacter arilaitensis Re117 GNAT family acetyltransferase YP_003916088.1 1013023 D 861360 CDS YP_003916089.1 308176683 9795204 complement(1013760..1014467) 1 NC_014550.1 identified by match to PF00583: acetyltransferase (GNAT) family; GNAT family acetyltransferase 1014467 9795204 AARI_08980 Arthrobacter arilaitensis Re117 GNAT family acetyltransferase YP_003916089.1 1013760 R 861360 CDS YP_003916090.1 308176684 9795205 complement(1014770..1015633) 1 NC_014550.1 hypothetical protein 1015633 9795205 AARI_08990 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916090.1 1014770 R 861360 CDS YP_003916091.1 308176685 9795207 complement(1016535..1017287) 1 NC_014550.1 match to PF01636. This family consists of bacterial antibiotic resistance proteins, which confer resistance to various aminoglycosides. The aminoglycoside phosphotransferases inactivate aminoglycoside antibiotics via phosphorylation. This family also includes homoserine kinase; phosphotransferase 1017287 9795207 AARI_09010 Arthrobacter arilaitensis Re117 phosphotransferase YP_003916091.1 1016535 R 861360 CDS YP_003916092.1 308176686 9795208 complement(1018064..1018969) 1 NC_014550.1 identified by match to PF00126: bacterial regulatory helix-turn-helix protein, lysR family. Numerous bacterial transcription regulatory proteins bind DNA via a helix-turn-helix (HTH) motif. These proteins are very diverse, but for convenience may be grouped into subfamilies on the basis of sequence similarity. One such family, the lysR family, groups together a range of proteins, including ampR, catM, catR, cynR, cysB, gltC, iciA, ilvY, irgB, lysR, metR, mkaC, mleR, nahR, nhaR, nodD, nolR, oxyR, pssR, rbcR, syrM, tcbR, tfdS and trpI. The majority of these proteins appear to be transcription activators and most are known to negatively regulate their own expression. All possess a potential HTH DNA-binding motif towards their N-termini; LysR family transcriptional regulator 1018969 9795208 AARI_09020 Arthrobacter arilaitensis Re117 LysR family transcriptional regulator YP_003916092.1 1018064 R 861360 CDS YP_003916093.1 308176687 9795209 1019105..1020157 1 NC_014550.1 catalyses the conversion of L-threonine to L-2- amino-3-oxobutanoate; L-threonine 3-dehydrogenase 1020157 tdh 9795209 tdh Arthrobacter arilaitensis Re117 L-threonine 3-dehydrogenase YP_003916093.1 1019105 D 861360 CDS YP_003916094.1 308176688 9794434 1020189..1021388 1 NC_014550.1 catalyzes the addition of acetyl-CoA to glycine to form 2-amino-3-oxobutanoate: the second reaction step of the main metabolic degradation pathway for threonine; glycine C-acetyltransferase 1021388 kbl 9794434 kbl Arthrobacter arilaitensis Re117 glycine C-acetyltransferase YP_003916094.1 1020189 D 861360 CDS YP_003916095.1 308176689 9794024 1021477..1022493 1 NC_014550.1 match to protein domain PF00356. Numerous bacterial transcription regulatory proteins bind DNA via a helix- turn-helix (HTH) motif. These proteins are very diverse, but for convenience may be grouped into subfamilies on the basis of sequence similarity. One such family groups together a range of proteins, including ascG, ccpA, cytR, ebgR, fruR, galR, galS, lacI, malI, opnR, purF, rafR, rbtR and scrR. Within this family, the HTH motif is situated towards the N-terminus; LacI family transcriptional regulator 1022493 9794024 AARI_09050 Arthrobacter arilaitensis Re117 LacI family transcriptional regulator YP_003916095.1 1021477 D 861360 CDS YP_003916096.1 308176690 9795210 1022564..1023985 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, carbohydrate uptake transporter-1 (CUT1) family (TC 3.A.1. 1.z). ABCISSE: ABC transporter, binding protein (BP), OSP-family (oligosaccharides or polyols); oligosaccharide/polyol ABC transporter substrate-binding protein 1023985 9795210 AARI_09060 Arthrobacter arilaitensis Re117 oligosaccharide/polyol ABC transporter substrate-binding protein YP_003916096.1 1022564 D 861360 CDS YP_003916097.1 308176691 9795211 1024053..1025192 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, carbohydrate uptake transporter-1 (CUT1) family (TC 3.A.1. 1.z). ABCISSE: ABC transporter, permease (IM), OSP- family (oligosaccharides or polyols); oligosaccharide/polyol ABC transporter inner membrane subunit 1025192 9795211 AARI_09070 Arthrobacter arilaitensis Re117 oligosaccharide/polyol ABC transporter inner membrane subunit YP_003916097.1 1024053 D 861360 CDS YP_003916098.1 308176692 9795212 1025189..1026136 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, carbohydrate uptake transporter-1 (CUT1) family (TC 3.A.1. 1.z). ABCISSE: ABC transporter, permease (IM), OSP- family (oligosaccharides or polyols); oligosaccharide/polyol ABC transporter inner membrane subunit 1026136 9795212 AARI_09080 Arthrobacter arilaitensis Re117 oligosaccharide/polyol ABC transporter inner membrane subunit YP_003916098.1 1025189 D 861360 CDS YP_003916099.1 308176693 9795213 1026273..1027460 1 NC_014550.1 catalyzes the third step in the histidine degradation pathway, the hydrolysis of (S)-3-(5-oxo-4,5- dihydro-3H-imidazol-4-yl)propanoate to N-formimidoyl-L- glutamate; imidazolonepropionase 1027460 hutI 9795213 hutI Arthrobacter arilaitensis Re117 imidazolonepropionase YP_003916099.1 1026273 D 861360 CDS YP_003916100.1 308176694 9793992 complement(1027582..1028208) 1 NC_014550.1 identified by match to protein domain PF08241; SAM-dependent methyltransferase 1028208 9793992 AARI_09100 Arthrobacter arilaitensis Re117 SAM-dependent methyltransferase YP_003916100.1 1027582 R 861360 CDS YP_003916101.1 308176695 9795214 1028307..1028804 1 NC_014550.1 in Escherichia coli, Tpx is an antioxidant protein with a thiol peroxidase activity; thiol peroxidase 1028804 tpx 9795214 tpx Arthrobacter arilaitensis Re117 thiol peroxidase YP_003916101.1 1028307 D 861360 CDS YP_003916102.1 308176696 9794459 complement(1028953..1029387) 1 NC_014550.1 signal peptide predicted by SignalP 3.0 HMM (probability: 0.999) with cleavage site probability 0.515 between position 29 and 30. Match to PS00383 pattern (aldehyde dehydrogenases glutamic acid active site); hypothetical protein 1029387 9794459 AARI_09120 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916102.1 1028953 R 861360 CDS YP_003916103.1 308176697 9795215 complement(1029609..1030502) 1 NC_014550.1 identified by match to PF01636. This family consists of bacterial antibiotic resistance proteins, which confer resistance to various aminoglycosides. It also includes homoserine kinase; aminoglycoside phosphotransferase-like protein 1030502 9795215 AARI_09130 Arthrobacter arilaitensis Re117 aminoglycoside phosphotransferase-like protein YP_003916103.1 1029609 R 861360 CDS YP_003916104.1 308176698 9795216 complement(1030499..1031344) 1 NC_014550.1 identified by match to PF01636. This family consists of bacterial antibiotic resistance proteins, which confer resistance to various aminoglycosides. It also includes homoserine kinase; aminoglycoside phosphotransferase-like protein 1031344 9795216 AARI_09140 Arthrobacter arilaitensis Re117 aminoglycoside phosphotransferase-like protein YP_003916104.1 1030499 R 861360 CDS YP_003916105.1 308176699 9795217 1031441..1032223 1 NC_014550.1 identified by match to protein family PF02517: CAAX amino terminal protease family. Members of this family are probably proteases (after a prenyl group is attached to the Cys residue in the C-terminal CAAX motif of a protein, the AAX tripeptide is removed by one of the CAAX prenyl proteases). The family contains the Q03530 CAAX prenyl protease. 6 transmembrane helices predicted by TMHMM2.0; CAAX amino terminal protease 1032223 9795217 AARI_09150 Arthrobacter arilaitensis Re117 CAAX amino terminal protease YP_003916105.1 1031441 D 861360 CDS YP_003916106.1 308176700 9795218 1032242..1032679 1 NC_014550.1 identified by match to PF00583: acetyltransferase (GNAT) family; GNAT family acetyltransferase 1032679 9795218 AARI_09160 Arthrobacter arilaitensis Re117 GNAT family acetyltransferase YP_003916106.1 1032242 D 861360 CDS YP_003916107.1 308176701 9795219 complement(1032729..1033373) 1 NC_014550.1 hypothetical protein 1033373 9795219 AARI_09170 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916107.1 1032729 R 861360 CDS YP_003916108.1 308176702 9795220 1033757..1035100 1 NC_014550.1 catalyses several reactions, including the formation of L-homocysteine from O-acetyl-L-homoserine and H2S, and the formation of L-methionine from O-acetyl-L- homoserine and methanethiol; O-acetylhomoserine aminocarboxypropyltransferase 1035100 9795220 AARI_09180 Arthrobacter arilaitensis Re117 O-acetylhomoserine aminocarboxypropyltransferase YP_003916108.1 1033757 D 861360 CDS YP_003916109.1 308176703 9795221 1035103..1036248 1 NC_014550.1 first reaction in L-methionine biosynthesis; homoserine O-acetyltransferase 1036248 metX 9795221 metX Arthrobacter arilaitensis Re117 homoserine O-acetyltransferase YP_003916109.1 1035103 D 861360 CDS YP_003916110.1 308176704 9794079 complement(1036332..1037189) 1 NC_014550.1 identified by match to protein family PF00657; GDSL-like lipase/esterase 1037189 9794079 AARI_09200 Arthrobacter arilaitensis Re117 GDSL-like lipase/esterase YP_003916110.1 1036332 R 861360 CDS YP_003916111.1 308176705 9795222 complement(1037258..1037674) 1 NC_014550.1 1 transmembrane helice predicted by TMHMM2.0; hypothetical protein 1037674 9795222 AARI_09210 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916111.1 1037258 R 861360 CDS YP_003916112.1 308176706 9795223 1037977..1039038 1 NC_014550.1 7 transmembrane helices predicted by TMHMM2.0; hypothetical protein 1039038 9795223 AARI_09220 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916112.1 1037977 D 861360 CDS YP_003916113.1 308176707 9795224 1039035..1039397 1 NC_014550.1 transcriptional regulator 1039397 9795224 AARI_09230 Arthrobacter arilaitensis Re117 transcriptional regulator YP_003916113.1 1039035 D 861360 CDS YP_003916114.1 308176708 9795225 1039471..1040121 1 NC_014550.1 identified by match to protein family PF02230. This family consists of both phospholipases and carboxylesterases with broad substrate specificity; phospholipase/carboxylesterase 1040121 9795225 AARI_09240 Arthrobacter arilaitensis Re117 phospholipase/carboxylesterase YP_003916114.1 1039471 D 861360 CDS YP_003916115.1 308176709 9795226 complement(1040122..1040352) 1 NC_014550.1 match to protein domain PF01479. The S4 domain was detected in proteins such as the bacterial ribosomal protein S4, two families of pseudouridine synthases, a novel family of predicted RNA methylases, a bacterial tyrosyl-tRNA synthetases, and a number of uncharacterized, small proteins that may be involved in translation regulation. The S4 domain probably mediates binding to RNA; S4 domain-containing protein 1040352 9795226 AARI_09250 Arthrobacter arilaitensis Re117 S4 domain-containing protein YP_003916115.1 1040122 R 861360 CDS YP_003916116.1 308176710 9795227 1040533..1041918 1 NC_014550.1 activates glycine and transfers it to tRNA(Gly) as the first step in protein biosynthesis; glycine--tRNA ligase 1041918 glyS 9795227 glyS Arthrobacter arilaitensis Re117 glycine--tRNA ligase YP_003916116.1 1040533 D 861360 CDS YP_003916117.1 308176711 9793928 1041925..1042854 1 NC_014550.1 hypothetical protein 1042854 9793928 AARI_09270 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916117.1 1041925 D 861360 CDS YP_003916118.1 308176712 9795228 1042935..1043936 1 NC_014550.1 signal peptide predicted by SignalP 3.0 HMM (probability: 0.937) with cleavage site probability 0.418 between position 40 and 41. 9 transmembrane helices predicted by TMHMM2.0 after the signal peptide; hypothetical protein 1043936 9795228 AARI_09280 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916118.1 1042935 D 861360 CDS YP_003916119.1 308176713 9795229 1044003..1045208 1 NC_014550.1 Chromate Ion Transporter (CHR) family (TC 2.A.51.y. z). match to PF02417: this region is found in known and predicted chromate transporters, these proteins reduce chromate accumulation and are essential for chromate resistance; chromate transporter 1045208 9795229 AARI_09290 Arthrobacter arilaitensis Re117 chromate transporter YP_003916119.1 1044003 D 861360 CDS YP_003916120.1 308176714 9795230 complement(1045205..1046848) 1 NC_014550.1 12 transmembrane helices predicted by TMHMM2.0; hypothetical protein 1046848 9795230 AARI_09300 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916120.1 1045205 R 861360 CDS YP_003916121.1 308176715 9795231 complement(1046848..1047312) 1 NC_014550.1 signal peptide predicted by SignalP 3.0 HMM (probability: 1.000) with cleavage site probability 0.867 between position 34 and 35; hypothetical protein 1047312 9795231 AARI_09310 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916121.1 1046848 R 861360 CDS YP_003916122.1 308176716 9795232 1047416..1048600 1 NC_014550.1 identified by match to protein family PF01207. Members of this family catalyse the reduction of the 5,6- double bond of a uridine residue on tRNA. The role of dihydrouridine in tRNA is currently unknown, but may increase conformational flexibility of the tRNA; tRNA-dihydrouridine synthase 1048600 9795232 AARI_09320 Arthrobacter arilaitensis Re117 tRNA-dihydrouridine synthase YP_003916122.1 1047416 D 861360 CDS YP_003916123.1 308176717 9795233 1048678..1049961 1 NC_014550.1 dGTPase catalyses the formation of deoxyguanosine from dGTP. It is involved in purine metabolism; dGTPase 1049961 dgt 9795233 dgt Arthrobacter arilaitensis Re117 dGTPase YP_003916123.1 1048678 D 861360 CDS YP_003916124.1 308176718 9793810 1049971..1051854 1 NC_014550.1 a nucleotidyltransferase which synthesizes the oligoribonucleotide primers required for DNA replication on the lagging strand of the replication fork. It can also prime the leading strand and has been implicated in cell division; DNA primase 1051854 dnaG 9793810 dnaG Arthrobacter arilaitensis Re117 DNA primase YP_003916124.1 1049971 D 861360 CDS YP_003916125.1 308176719 9793602 complement(1052110..1052937) 1 NC_014550.1 8 transmembrane helices predicted by TMHMM2.0; hypothetical protein 1052937 9793602 AARI_09350 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916125.1 1052110 R 861360 CDS YP_003916126.1 308176720 9795234 1053167..1053976 1 NC_014550.1 3 transmembrane helices predicted by TMHMM2.0; hypothetical protein 1053976 9795234 AARI_09360 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916126.1 1053167 D 861360 CDS YP_003916127.1 308176721 9795235 complement(1054193..1054351) 1 NC_014550.1 hypothetical protein 1054351 9795235 AARI_09370 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916127.1 1054193 R 861360 CDS YP_003916128.1 308176722 9795236 1054428..1055948 1 NC_014550.1 protein-histidine kinases are key elements in two- component signal transduction systems, which enable bacteria to sense, respond, and adapt to a wide range of environments, stressors, and growth conditions; signal transduction histidine kinase 1055948 9795236 AARI_09380 Arthrobacter arilaitensis Re117 signal transduction histidine kinase YP_003916128.1 1054428 D 861360 CDS YP_003916129.1 308176723 9795237 1055945..1057504 1 NC_014550.1 11 transmembrane helices predicted by TMHMM2.0; hypothetical protein 1057504 9795237 AARI_09390 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916129.1 1055945 D 861360 CDS YP_003916130.1 308176724 9795240 complement(1058833..1059207) 1 NC_014550.1 hypothetical protein 1059207 9795240 AARI_09420 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916130.1 1058833 R 861360 CDS YP_003916131.1 308176725 9795241 1059344..1060000 1 NC_014550.1 hypothetical protein 1060000 9795241 AARI_09430 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916131.1 1059344 D 861360 CDS YP_003916132.1 308176726 9795242 complement(1060096..1060533) 1 NC_014550.1 catalyzes the condensation of 5-amino-6-(1-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4- dihydrohy-2-butanone-4-phosphate yielding 6,7-dimethyl-8- lumazine; riboflavin synthase subunit beta 1060533 ribH 9795242 ribH Arthrobacter arilaitensis Re117 riboflavin synthase subunit beta YP_003916132.1 1060096 R 861360 CDS YP_003916133.1 308176727 9794299 complement(1060644..1061648) 1 NC_014550.1 identified by match to PF00296. Bacterial luciferase is a flavin monooxygenase that catalyses the oxidation of long-chain aldehydes and releases energy in the form of visible light, and which uses flavin as a substrate rather than a cofactor. There are structural similarities between bacterial luciferase and nonfluorescent flavoproteins (LuxF, FP390), alkanesulfonate monooxygenase (SsuD), and coenzyme F420- dependent terahydromethanopterin reductase, which make up clearly related families with somewhat different folds; luciferase-like monooxygenase 1061648 9794299 AARI_09450 Arthrobacter arilaitensis Re117 luciferase-like monooxygenase YP_003916133.1 1060644 R 861360 CDS YP_003916134.1 308176728 9795243 complement(1061723..1062007) 1 NC_014550.1 match to PF01381: helix-turn-helix. This is large family of DNA binding helix-turn helix proteins that include a bacterial plasmid copy control protein, bacterial methylases, various bacteriophage transcription control proteins and a vegetative specific protein from Dictyostelium discoideum (Slime mould); hypothetical protein 1062007 9795243 AARI_09460 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916134.1 1061723 R 861360 CDS YP_003916135.1 308176729 9795244 1062054..1062836 1 NC_014550.1 responsible for the removal of the amino-terminal (initiator) methionine from nascent eukaryotic cytosolic and cytoplasmic prokaryotic proteins if the penultimate amino acid is small and uncharged; methionyl aminopeptidase 1062836 map 9795244 map Arthrobacter arilaitensis Re117 methionyl aminopeptidase YP_003916135.1 1062054 D 861360 CDS YP_003916136.1 308176730 9794058 complement(1062833..1063561) 1 NC_014550.1 catalyses the following reaction: ATP + 7,8- diaminononanoate + CO(2) <=> ADP + phosphate + dethiobiotin; dethiobiotin synthase 1063561 bioD 9794058 bioD Arthrobacter arilaitensis Re117 dethiobiotin synthase YP_003916136.1 1062833 R 861360 CDS YP_003916137.1 308176731 9793718 complement(1063558..1064736) 1 NC_014550.1 cytochrome P450 1064736 9793718 AARI_09490 Arthrobacter arilaitensis Re117 cytochrome P450 YP_003916137.1 1063558 R 861360 CDS YP_003916138.1 308176732 9795245 complement(1064736..1065908) 1 NC_014550.1 catalyzes an intermediate step in the biosynthesis of biotin, the addition of 6-carboxy-hexanoyl-CoA (pimeloyl-coA) to alanine to form 8-amino-7-oxononanoate: 6-carboxyhexanoyl-CoA + L-alanine <=> 8-amino-7- oxononanoate + CoA + CO(2); 8-amino-7-oxononanoate synthase 1065908 bioF 9795245 bioF Arthrobacter arilaitensis Re117 8-amino-7-oxononanoate synthase YP_003916138.1 1064736 R 861360 CDS YP_003916139.1 308176733 9793719 complement(1065901..1067265) 1 NC_014550.1 catalyzes an intermediate step in the biosynthesis of biotin, the transamination of 7-keto-8-aminopelargonic acid (7-KAP) to form 7,8- diaminopelargonic acid (DAPA): S- adenosyl-L-methionine + 8-amino-7-oxononanoate <=> S- adenosyl-4-methylthio-2-oxobutanoate + 7,8- diaminononanoate; adenosylmethionine--8-amino-7-oxononanoate transaminase 1067265 bioA 9793719 bioA Arthrobacter arilaitensis Re117 adenosylmethionine--8-amino-7-oxononanoate transaminase YP_003916139.1 1065901 R 861360 CDS YP_003916140.1 308176734 9793716 complement(1067262..1068494) 1 NC_014550.1 catalyses the following reaction: dethiobiotin + sulfur + 2 S-adenosyl-L-methionine <=> biotin + 2 L- methionine + 2 5-deoxyadenosine; biotin synthase 1068494 bioB 9793716 bioB Arthrobacter arilaitensis Re117 biotin synthase YP_003916140.1 1067262 R 861360 CDS YP_003916141.1 308176735 9793717 complement(1068645..1069217) 1 NC_014550.1 match to PF03807: NADP oxidoreductase coenzyme F420- dependent; hypothetical protein 1069217 9793717 AARI_09530 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916141.1 1068645 R 861360 CDS YP_003916142.1 308176736 9795246 1069468..1070097 1 NC_014550.1 hypothetical protein 1070097 9795246 AARI_09540 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916142.1 1069468 D 861360 CDS YP_003916143.1 308176737 9795247 complement(1070165..1072513) 1 NC_014550.1 may be involved in aerobactin-like siderophore biosynthesis; siderophore biosynthesis protein 1072513 9795247 AARI_09550 Arthrobacter arilaitensis Re117 siderophore biosynthesis protein YP_003916143.1 1070165 R 861360 CDS YP_003916144.1 308176738 9795248 complement(1072527..1073873) 1 NC_014550.1 L-lysine 6-monooxygenase (NADPH) catalyzes the conversion of lysine to its N6-hydroxy derivative, the initial event in the biosynthesis of aerobactin, a siderophore which functions as a virulence determinant in many septicemic organisms; L-lysine 6-monooxygenase (NADPH) 1073873 9795248 AARI_09560 Arthrobacter arilaitensis Re117 L-lysine 6-monooxygenase (NADPH) YP_003916144.1 1072527 R 861360 CDS YP_003916145.1 308176739 9795249 complement(1073870..1075390) 1 NC_014550.1 identified by match to protein family PF00282; pyridoxal-dependent amino acid decarboxylase 1075390 9795249 AARI_09570 Arthrobacter arilaitensis Re117 pyridoxal-dependent amino acid decarboxylase YP_003916145.1 1073870 R 861360 CDS YP_003916146.1 308176740 9795250 1075719..1076972 1 NC_014550.1 major facilitator superfamily (TC 2.A.1.y.z). Identified by match to protein family PF07690 (Major Facilitator Superfamily); MFS superfamily transporter 1076972 9795250 AARI_09580 Arthrobacter arilaitensis Re117 MFS superfamily transporter YP_003916146.1 1075719 D 861360 CDS YP_003916147.1 308176741 9795251 1077015..1078088 1 NC_014550.1 match to PF00534: Glycosyl transferases group 1. Proteins containing this domain transfer UDP, ADP, GDP or CMP linked sugars to a variety of substrates, including glycogen, fructose-6-phosphate and lipopolysaccharides. The bacterial enzymes are involved in various biosynthetic processes that include exopolysaccharide biosynthesis, lipopolysaccharide core biosynthesis and the biosynthesis of the slime polysaccaride colanic acid; glycosyl transferase family 1 1078088 9795251 AARI_09590 Arthrobacter arilaitensis Re117 glycosyl transferase family 1 YP_003916147.1 1077015 D 861360 CDS YP_003916148.1 308176742 9793603 1078575..1079420 1 NC_014550.1 3 transmembrane helices predicted by TMHMM2.0; hypothetical protein 1079420 9793603 AARI_09600 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916148.1 1078575 D 861360 CDS YP_003916149.1 308176743 9795253 1079507..1080418 1 NC_014550.1 signal peptide predicted by SignalP 3.0 HMM (probability: 0.990) with cleavage site probability 0.909 between position 29 and 30. 7 transmembrane helices predicted by TMHMM2.0 after the signal peptide; hypothetical protein 1080418 9795253 AARI_09610 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916149.1 1079507 D 861360 CDS YP_003916150.1 308176744 9795254 1080477..1081658 1 NC_014550.1 match to PF00534: Glycosyl transferases group 1. Proteins containing this domain transfer UDP, ADP, GDP or CMP linked sugars to a variety of substrates, including glycogen, fructose-6-phosphate and lipopolysaccharides. The bacterial enzymes are involved in various biosynthetic processes that include exopolysaccharide biosynthesis, lipopolysaccharide core biosynthesis and the biosynthesis of the slime polysaccaride colanic acid; glycosyl transferase family 1 1081658 9795254 AARI_09620 Arthrobacter arilaitensis Re117 glycosyl transferase family 1 YP_003916150.1 1080477 D 861360 CDS YP_003916151.1 308176745 9793604 complement(1082277..1082774) 1 NC_014550.1 identified by match to protein family PF01551. Members of this family are zinc metallopeptidases with a range of specificities. Peptidase family M23 are also endopeptidases. Signal peptide predicted by SignalP 3.0 HMM (probability: 0.993) with cleavage site probability 0. 690 between position 27 and 28; peptidase M23 1082774 9793604 AARI_09630 Arthrobacter arilaitensis Re117 peptidase M23 YP_003916151.1 1082277 R 861360 CDS YP_003916152.1 308176746 9795256 1083214..1084038 1 NC_014550.1 30S ribosomal protein S2 1084038 rpsB 9795256 rpsB Arthrobacter arilaitensis Re117 30S ribosomal protein S2 YP_003916152.1 1083214 D 861360 CDS YP_003916153.1 308176747 9794349 1084184..1085020 1 NC_014550.1 associates with the elongation factor-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome; elongation factor Ts 1085020 tsf 9794349 tsf Arthrobacter arilaitensis Re117 elongation factor Ts YP_003916153.1 1084184 D 861360 CDS YP_003916154.1 308176748 9794482 1085224..1085946 1 NC_014550.1 catalyses the reversible transfer of the gamma- phosphoryl group from an ATP donor to UMP, yielding UDP, which is the starting point for the synthesis of all other pyrimidine nucleotides; uridylate kinase 1085946 pyrH 9794482 pyrH Arthrobacter arilaitensis Re117 uridylate kinase YP_003916154.1 1085224 D 861360 CDS YP_003916155.1 308176749 9794273 1086024..1086581 1 NC_014550.1 responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; ribosome-recycling factor 1086581 frr 9794273 frr Arthrobacter arilaitensis Re117 ribosome-recycling factor YP_003916155.1 1086024 D 861360 CDS YP_003916156.1 308176750 9793862 1086581..1087846 1 NC_014550.1 phosphatidate cytidylyltransferase catalyzes the synthesis of CDP-diacylglycerol from CTP and phosphatidate. It produces key intermediates in phospholipid biosynthesis; phosphatidate cytidylyltransferase 1087846 cdsA 9793862 cdsA Arthrobacter arilaitensis Re117 phosphatidate cytidylyltransferase YP_003916156.1 1086581 D 861360 CDS YP_003916157.1 308176751 9793733 1087970..1088542 1 NC_014550.1 hypothetical protein 1088542 9793733 AARI_09690 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916157.1 1087970 D 861360 CDS YP_003916158.1 308176752 9795257 complement(1088613..1089821) 1 NC_014550.1 major facilitator superfamily (TC 2.A.1.y.z). Identified by match to protein family PF07690 (Major Facilitator Superfamily); MFS superfamily transporter 1089821 9795257 AARI_09700 Arthrobacter arilaitensis Re117 MFS superfamily transporter YP_003916158.1 1088613 R 861360 CDS YP_003916159.1 308176753 9795258 complement(1089822..1090493) 1 NC_014550.1 identified by match to protein family PF00392. This family of regulatory proteins consists of the N-terminal HTH region of GntR-like bacterial transcription factors. At the C-terminus there is usually an effector- binding/oligomerisation domain. The GntR-like proteins can be divided into six sub-families: MocR, YtrR, FadR, AraR, HutC and PlmA. Many of these proteins have been shown experimentally to be autoregulatory, enabling the prediction of operator sites and the discovery of cis/trans relationships; GntR family transcriptional regulator 1090493 9795258 AARI_09710 Arthrobacter arilaitensis Re117 GntR family transcriptional regulator YP_003916159.1 1089822 R 861360 CDS YP_003916160.1 308176754 9795259 complement(1090603..1092078) 1 NC_014550.1 Solute:Sodium Symporter (SSS) family (2.A.21.y.z). Members of the SSS family catalyze solute:Na+ symport. The solutes transported may be sugars, amino acids, organo cations such as choline, nucleosides, inositols, vitamins, urea or anions, depending on the system; Na+/solute symporter 1092078 9795259 AARI_09720 Arthrobacter arilaitensis Re117 Na+/solute symporter YP_003916160.1 1090603 R 861360 CDS YP_003916161.1 308176755 9795260 complement(1092071..1092478) 1 NC_014550.1 2 transmembrane helices predicted by TMHMM2.0; hypothetical protein 1092478 9795260 AARI_09730 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916161.1 1092071 R 861360 CDS YP_003916162.1 308176756 9795261 complement(1092494..1093210) 1 NC_014550.1 response regulators are key elements in two- component signal transduction systems, which enable bacteria to sense, respond, and adapt to a wide range of environments, stressors, and growth conditions; two-component system response regulator 1093210 9795261 AARI_09740 Arthrobacter arilaitensis Re117 two-component system response regulator YP_003916162.1 1092494 R 861360 CDS YP_003916163.1 308176757 9795262 complement(1093240..1094421) 1 NC_014550.1 protein-histidine kinases are key elements in two- component signal transduction systems, which enable bacteria to sense, respond, and adapt to a wide range of environments, stressors, and growth conditions. 1 transmembrane helice predicted by TMHMM2.0; signal transduction histidine kinase 1094421 9795262 AARI_09750 Arthrobacter arilaitensis Re117 signal transduction histidine kinase YP_003916163.1 1093240 R 861360 CDS YP_003916164.1 308176758 9795263 1094617..1094961 1 NC_014550.1 2 transmembrane helices predicted by TMHMM2.0; hypothetical protein 1094961 9795263 AARI_09760 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916164.1 1094617 D 861360 CDS YP_003916165.1 308176759 9795264 1094962..1096587 1 NC_014550.1 Solute:Sodium Symporter (SSS) family (2.A.21.y.z). Members of the SSS family catalyze solute:Na+ symport. The solutes transported may be sugars, amino acids, organo cations such as choline, nucleosides, inositols, vitamins, urea or anions, depending on the system; Na+/solute symporter 1096587 9795264 AARI_09770 Arthrobacter arilaitensis Re117 Na+/solute symporter YP_003916165.1 1094962 D 861360 CDS YP_003916166.1 308176760 9795265 complement(1096672..1097145) 1 NC_014550.1 identified by match to protein family PF01037; AsnC/Lrp family transcriptional regulator 1097145 9795265 AARI_09780 Arthrobacter arilaitensis Re117 AsnC/Lrp family transcriptional regulator YP_003916166.1 1096672 R 861360 CDS YP_003916167.1 308176761 9795266 1097296..1098411 1 NC_014550.1 the pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3); pyruvate dehydrogenase E1 component subunit alpha 1098411 9795266 AARI_09790 Arthrobacter arilaitensis Re117 pyruvate dehydrogenase E1 component subunit alpha YP_003916167.1 1097296 D 861360 CDS YP_003916168.1 308176762 9795267 1098414..1099415 1 NC_014550.1 the pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3); pyruvate dehydrogenase E1 component subunit beta 1099415 9795267 AARI_09800 Arthrobacter arilaitensis Re117 pyruvate dehydrogenase E1 component subunit beta YP_003916168.1 1098414 D 861360 CDS YP_003916169.1 308176763 9795268 1099415..1100764 1 NC_014550.1 the pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3); dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex 1100764 9795268 AARI_09810 Arthrobacter arilaitensis Re117 dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex YP_003916169.1 1099415 D 861360 CDS YP_003916170.1 308176764 9795269 1100961..1102592 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, peptide/opine/nickel uptake transporter (PepT) family (TC 3.A.1.5.z). ABCISSE: ABC transporter, binding protein (BP), OPN-family (oligopeptides and nickel), oligopeptides import; dipeptide/oligopeptide ABC transporter substrate-binding protein 1102592 9795269 AARI_09820 Arthrobacter arilaitensis Re117 dipeptide/oligopeptide ABC transporter substrate-binding protein YP_003916170.1 1100961 D 861360 CDS YP_003916171.1 308176765 9795270 1102785..1103711 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, peptide/opine/nickel uptake transporter (PepT) family (TC 3.A.1.5.z). ABCISSE: ABC transporter, permease (IM), OPN- family (oligopeptides and nickel), oligopeptides import; dipeptide/oligopeptide ABC transporter inner membrane subunit 1103711 9795270 AARI_09830 Arthrobacter arilaitensis Re117 dipeptide/oligopeptide ABC transporter inner membrane subunit YP_003916171.1 1102785 D 861360 CDS YP_003916172.1 308176766 9795271 1103704..1104726 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, peptide/opine/nickel uptake transporter (PepT) family (TC 3.A.1.5.z). ABCISSE: ABC transporter, permease (IM), OPN- family (oligopeptides and nickel), oligopeptides import; dipeptide/oligopeptide ABC transporter inner membrane subunit 1104726 9795271 AARI_09840 Arthrobacter arilaitensis Re117 dipeptide/oligopeptide ABC transporter inner membrane subunit YP_003916172.1 1103704 D 861360 CDS YP_003916173.1 308176767 9795272 1104730..1106373 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, peptide/opine/nickel uptake transporter (PepT) family (TC 3.A.1.5.z). ABCISSE: ABC transporter, fused ATP-binding protein (ABC2), OPN-family (oligopeptides and nickel), oligopeptides import; dipeptide/oligopeptide ABC transporter ATP-binding subunit 1106373 9795272 AARI_09850 Arthrobacter arilaitensis Re117 dipeptide/oligopeptide ABC transporter ATP-binding subunit YP_003916173.1 1104730 D 861360 CDS YP_003916174.1 308176768 9795273 1106978..1108315 1 NC_014550.1 identified by similarity to protein SP:Q6DKY2 (Bacillus stearothermophilus). Heat-stable reverse transcriptase. Possible group II intron associated protein; reverse transcriptase/maturase 1108315 trt 9795273 trt Arthrobacter arilaitensis Re117 reverse transcriptase/maturase YP_003916174.1 1106978 D 861360 CDS YP_003916175.1 308176769 9794475 1108770..1110572 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, peptide/opine/nickel uptake transporter (PepT) family (TC 3.A.1.5.z). ABCISSE: ABC transporter, binding protein (BP), OPN-family (oligopeptides and nickel), oligopeptides import; dipeptide/oligopeptide ABC transporter substrate-binding protein 1110572 9794475 AARI_09870 Arthrobacter arilaitensis Re117 dipeptide/oligopeptide ABC transporter substrate-binding protein YP_003916175.1 1108770 D 861360 CDS YP_003916176.1 308176770 9795274 1110715..1112232 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, peptide/opine/nickel uptake transporter (PepT) family (TC 3.A.1.5.z). ABCISSE: ABC transporter, permease (IM), OPN- family (oligopeptides and nickel), oligopeptides import; dipeptide/oligopeptide ABC transporter inner membrane subunit 1112232 9795274 AARI_09880 Arthrobacter arilaitensis Re117 dipeptide/oligopeptide ABC transporter inner membrane subunit YP_003916176.1 1110715 D 861360 CDS YP_003916177.1 308176771 9795275 1112284..1113354 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, peptide/opine/nickel uptake transporter (PepT) family (TC 3.A.1.5.z). ABCISSE: ABC transporter, permease (IM), OPN- family (oligopeptides and nickel), oligopeptides import; dipeptide/oligopeptide ABC transporter inner membrane subunit 1113354 9795275 AARI_09890 Arthrobacter arilaitensis Re117 dipeptide/oligopeptide ABC transporter inner membrane subunit YP_003916177.1 1112284 D 861360 CDS YP_003916178.1 308176772 9795276 1113351..1115048 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, peptide/opine/nickel uptake transporter (PepT) family (TC 3.A.1.5.z). ABCISSE: ABC transporter, fused ATP-binding protein (ABC2), OPN-family (oligopeptides and nickel), oligopeptides import; dipeptide/oligopeptide ABC transporter ATP-binding subunit 1115048 9795276 AARI_09900 Arthrobacter arilaitensis Re117 dipeptide/oligopeptide ABC transporter ATP-binding subunit YP_003916178.1 1113351 D 861360 CDS YP_003916179.1 308176773 9795277 1115181..1115672 1 NC_014550.1 match to protein domain PF01814: Hemerythrin HHE cation binding domain. Members of this family occur all across nature and are involved in a variety of processes. For instance, in Nereis diversicolor, protein P80255 binds cadmium so as to protect the organism from toxicity; cation binding domain-containing protein 1115672 9795277 AARI_09910 Arthrobacter arilaitensis Re117 cation binding domain-containing protein YP_003916179.1 1115181 D 861360 CDS YP_003916180.1 308176774 9795278 1115703..1115897 1 NC_014550.1 hypothetical protein 1115897 9795278 AARI_09920 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916180.1 1115703 D 861360 CDS YP_003916181.1 308176775 9795279 complement(1115967..1116428) 1 NC_014550.1 identified by match to PF00583: acetyltransferase (GNAT) family; GNAT family acetyltransferase 1116428 9795279 AARI_09930 Arthrobacter arilaitensis Re117 GNAT family acetyltransferase YP_003916181.1 1115967 R 861360 CDS YP_003916182.1 308176776 9795280 complement(1116498..1117118) 1 NC_014550.1 match to PF00440: bacterial regulatory proteins, tetR family; transcriptional regulator 1117118 9795280 AARI_09940 Arthrobacter arilaitensis Re117 transcriptional regulator YP_003916182.1 1116498 R 861360 CDS YP_003916183.1 308176777 9795281 1117358..1118512 1 NC_014550.1 possibly involved in the metabolism of lipids. Match to protein domains PF08028, PF02771 and PF02770. Acyl-CoA dehydrogenases catalyze the alpha,beta- dehydrogenation of acyl-CoA thioesters to the corresponding trans 2,3-enoyl CoA-products with concommitant reduction of enzyme-bound FAD; acyl-CoA dehydrogenase 1118512 9795281 AARI_09950 Arthrobacter arilaitensis Re117 acyl-CoA dehydrogenase YP_003916183.1 1117358 D 861360 CDS YP_003916184.1 308176778 9795282 1118594..1119817 1 NC_014550.1 catalyses the formation of 2-C-methyl-D-erythritol 4-phosphate from 1-deoxy-D-xylulose-5-phosphate in the presence of NADPH. Forms part of a non-mevalonate pathway for terpenoid biosynthesis; 1-deoxy-D-xylulose-5-phosphate reductoisomerase 1119817 dxr 9795282 dxr Arthrobacter arilaitensis Re117 1-deoxy-D-xylulose-5-phosphate reductoisomerase YP_003916184.1 1118594 D 861360 CDS YP_003916185.1 308176779 9793831 1119814..1121163 1 NC_014550.1 match to protein family PF02163: Peptidase family M50. Match to PS00142 pattern: neutral zinc metallopeptidases, zinc-binding region signature. 4 transmembrane helices predicted by TMHMM2.0; zinc metallopeptidase 1121163 9793831 AARI_09970 Arthrobacter arilaitensis Re117 zinc metallopeptidase YP_003916185.1 1119814 D 861360 CDS YP_003916186.1 308176780 9795283 1121187..1121486 1 NC_014550.1 identified by match to protein domain PF03795; YCII-related domain-containing protein 1121486 9795283 AARI_09980 Arthrobacter arilaitensis Re117 YCII-related domain-containing protein YP_003916186.1 1121187 D 861360 CDS YP_003916187.1 308176781 9795284 1121601..1122023 1 NC_014550.1 match to protein domain PF00472. This domain is found in peptide chain release factors, and a number of smaller proteins of unknown function; peptidyl-tRNA hydrolase domain-containing protein 1122023 9795284 AARI_09990 Arthrobacter arilaitensis Re117 peptidyl-tRNA hydrolase domain-containing protein YP_003916187.1 1121601 D 861360 CDS YP_003916188.1 308176782 9795285 1122145..1122699 1 NC_014550.1 identified by match to PF03358. FMN reductase reductase catalyses the following reaction: NAD(P)H + FMN = NAD(P)(+) + FMNH(2); FMN reductase 1122699 9795285 AARI_10000 Arthrobacter arilaitensis Re117 FMN reductase YP_003916188.1 1122145 D 861360 CDS YP_003916189.1 308176783 9795286 1122840..1124006 1 NC_014550.1 part of the non-mevalonate pathway for terpenoid biosynthesis; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 1124006 ispG 9795286 ispG Arthrobacter arilaitensis Re117 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase YP_003916189.1 1122840 D 861360 CDS YP_003916190.1 308176784 9794013 1124044..1124856 1 NC_014550.1 identified by match to PF00583: acetyltransferase (GNAT) family; GNAT family acetyltransferase 1124856 9794013 AARI_10020 Arthrobacter arilaitensis Re117 GNAT family acetyltransferase YP_003916190.1 1124044 D 861360 CDS YP_003916191.1 308176785 9795287 1124959..1125651 1 NC_014550.1 hypothetical protein 1125651 9795287 AARI_10030 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916191.1 1124959 D 861360 CDS YP_003916192.1 308176786 9795288 1125704..1126453 1 NC_014550.1 hypothetical protein 1126453 9795288 AARI_10040 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916192.1 1125704 D 861360 CDS YP_003916193.1 308176787 9795289 1126789..1126905 1 NC_014550.1 hypothetical protein 1126905 9795289 AARI_10050 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916193.1 1126789 D 861360 CDS YP_003916194.1 308176788 9795290 1126927..1127478 1 NC_014550.1 hypothetical protein 1127478 9795290 AARI_10060 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916194.1 1126927 D 861360 CDS YP_003916195.1 308176789 9793419 1128780..1128872 1 NC_014550.1 hypothetical protein 1128872 9793419 AARI_10070 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916195.1 1128780 D 861360 CDS YP_003916196.1 308176790 9795292 1128984..1130150 1 NC_014550.1 match to protein domains PF01590 and PF00486; transcriptional regulator 1130150 9795292 AARI_10080 Arthrobacter arilaitensis Re117 transcriptional regulator YP_003916196.1 1128984 D 861360 CDS YP_003916197.1 308176791 9795293 1130270..1132060 1 NC_014550.1 FAD-dependent pyridine nucleotide-disulphide oxidoreductase 1132060 9795293 AARI_10090 Arthrobacter arilaitensis Re117 FAD-dependent pyridine nucleotide-disulphide oxidoreductase YP_003916197.1 1130270 D 861360 CDS YP_003916198.1 308176792 9795294 complement(1132354..1132470) 1 NC_014550.1 hypothetical protein 1132470 9795294 AARI_10100 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916198.1 1132354 R 861360 CDS YP_003916199.1 308176793 9795295 1132879..1134666 1 NC_014550.1 activates proline and transfers it to tRNA(Pro) as the first step in protein biosynthesis; proline--tRNA ligase 1134666 proS 9795295 proS Arthrobacter arilaitensis Re117 proline--tRNA ligase YP_003916199.1 1132879 D 861360 CDS YP_003916200.1 308176794 9794229 1134703..1135518 1 NC_014550.1 6 transmembrane helices predicted by TMHMM2.0; hypothetical protein 1135518 9794229 AARI_10120 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916200.1 1134703 D 861360 CDS YP_003916201.1 308176795 9795296 complement(1135519..1135950) 1 NC_014550.1 hypothetical protein 1135950 9795296 AARI_10130 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916201.1 1135519 R 861360 CDS YP_003916202.1 308176796 9795297 1136091..1137125 1 NC_014550.1 transposase of ISAar31, IS630 family 1137125 9795297 AARI_34780 Arthrobacter arilaitensis Re117 transposase of ISAar31, IS630 family YP_003916202.1 1136091 D 861360 CDS YP_003916203.1 308176797 9793420 complement(1137567..1138640) 1 NC_014550.1 1 transmembrane helice predicted by TMHMM2.0; hypothetical protein 1138640 9793420 AARI_10140 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916203.1 1137567 R 861360 CDS YP_003916204.1 308176798 9795298 1138816..1139382 1 NC_014550.1 hypothetical protein 1139382 9795298 AARI_10150 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916204.1 1138816 D 861360 CDS YP_003916205.1 308176799 9795299 1139385..1140368 1 NC_014550.1 participates in both the termination and antitermination of transcription. Interacts with RNA polymerase and binds RNA; transcription elongation protein NusA 1140368 nusA 9795299 nusA Arthrobacter arilaitensis Re117 transcription elongation protein NusA YP_003916205.1 1139385 D 861360 CDS YP_003916206.1 308176800 9794153 1140509..1140829 1 NC_014550.1 hypothetical protein 1140829 9794153 AARI_10170 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916206.1 1140509 D 861360 CDS YP_003916207.1 308176801 9795300 1141006..1143948 1 NC_014550.1 one of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 1143948 infB 9795300 infB Arthrobacter arilaitensis Re117 translation initiation factor IF-2 YP_003916207.1 1141006 D 861360 CDS YP_003916208.1 308176802 9794009 1144050..1144484 1 NC_014550.1 associates with free 30S ribosomal subunits. Essential for efficient processing of 16S rRNA; ribosome-binding factor A 1144484 rbfA 9794009 rbfA Arthrobacter arilaitensis Re117 ribosome-binding factor A YP_003916208.1 1144050 D 861360 CDS YP_003916209.1 308176803 9794283 1144674..1145141 1 NC_014550.1 hypothetical protein 1145141 9794283 AARI_10200 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916209.1 1144674 D 861360 CDS YP_003916210.1 308176804 9795301 complement(1145665..1146120) 1 NC_014550.1 identified by match to protein family PF01047. Regulators with the marR-type HTH domain are present in bacteria and archaea and control a variety of biological functions, including resistance to multiple antibiotics, household disinfectants, organic solvents, oxidative stress agents and regulation of the virulence factor synthesis in pathogens of humans and plants. Many of the marR-like regulators respond to aromatic compounds; MarR family transcriptional regulator 1146120 9795301 AARI_10210 Arthrobacter arilaitensis Re117 MarR family transcriptional regulator YP_003916210.1 1145665 R 861360 CDS YP_003916211.1 308176805 9795303 complement(1146696..1148180) 1 NC_014550.1 match to protein domain PF00174, which corresponds to the molybdopterin binding domain of oxidoreductases that require a molybdopterin cofactor; molybdopterin oxidoreductase 1148180 9795303 AARI_10230 Arthrobacter arilaitensis Re117 molybdopterin oxidoreductase YP_003916211.1 1146696 R 861360 CDS YP_003916212.1 308176806 9795304 complement(1148379..1149200) 1 NC_014550.1 1 transmembrane helice predicted by TMHMM2.0; hypothetical protein 1149200 9795304 AARI_10240 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916212.1 1148379 R 861360 CDS YP_003916213.1 308176807 9795305 complement(1149200..1149757) 1 NC_014550.1 match to protein family TIGR02937. Sigma-70 family; RNA polymerase sigma factor 1149757 9795305 AARI_10250 Arthrobacter arilaitensis Re117 RNA polymerase sigma factor YP_003916213.1 1149200 R 861360 CDS YP_003916214.1 308176808 9795306 complement(1149951..1150613) 1 NC_014550.1 match to protein domain PF02469: Fasciclin domain. This extracellular domain is found repeated four times in grasshopper fasciclin I as well as in proteins from mammals, sea urchins, plants, yeast and bacteria (for example in the bacterial immunogenic protein MPT70); lipoprotein 1150613 9795306 AARI_10260 Arthrobacter arilaitensis Re117 lipoprotein YP_003916214.1 1149951 R 861360 CDS YP_003916215.1 308176809 9795307 1150927..1151850 1 NC_014550.1 responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; tRNA pseudouridylate synthase B 1151850 truB 9795307 truB Arthrobacter arilaitensis Re117 tRNA pseudouridylate synthase B YP_003916215.1 1150927 D 861360 CDS YP_003916216.1 308176810 9794477 1151868..1152230 1 NC_014550.1 4 transmembrane helices predicted by TMHMM2.0; hypothetical protein 1152230 9794477 AARI_10280 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916216.1 1151868 D 861360 CDS YP_003916217.1 308176811 9795308 1152241..1152708 1 NC_014550.1 4 transmembrane helices predicted by TMHMM2.0; hypothetical protein 1152708 9795308 AARI_10290 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916217.1 1152241 D 861360 CDS YP_003916218.1 308176812 9795309 1152772..1153725 1 NC_014550.1 EC 2.7.1.26 catalyses the following reaction : ATP + riboflavin = ADP + FMN. EC 2.7.7.2 catalyses the following reaction : ATP + FMN = diphosphate + FAD; bifunctionnal riboflavin kinase/FAD synthetase 1153725 ribF 9795309 ribF Arthrobacter arilaitensis Re117 bifunctionnal riboflavin kinase/FAD synthetase YP_003916218.1 1152772 D 861360 CDS YP_003916219.1 308176813 9794298 1153730..1154515 1 NC_014550.1 identified by match to protein domain PF08241; SAM-dependent methyltransferase 1154515 9794298 AARI_10310 Arthrobacter arilaitensis Re117 SAM-dependent methyltransferase YP_003916219.1 1153730 D 861360 CDS YP_003916220.1 308176814 9795310 1154623..1154892 1 NC_014550.1 one of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA; 30S ribosomal protein S15 1154892 rpsO 9795310 rpsO Arthrobacter arilaitensis Re117 30S ribosomal protein S15 YP_003916220.1 1154623 D 861360 CDS YP_003916221.1 308176815 9794362 1155283..1155414 1 NC_014550.1 hypothetical protein 1155414 9794362 AARI_10330 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916221.1 1155283 D 861360 CDS YP_003916222.1 308176816 9795311 1155488..1156045 1 NC_014550.1 hypothetical protein 1156045 9795311 AARI_10340 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916222.1 1155488 D 861360 CDS YP_003916223.1 308176817 9795312 1156042..1156650 1 NC_014550.1 3 transmembrane helices predicted by TMHMM2.0; hypothetical protein 1156650 9795312 AARI_10350 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916223.1 1156042 D 861360 CDS YP_003916224.1 308176818 9795313 complement(1156849..1157595) 1 NC_014550.1 match to PF01965: DJ-1/PfpI family. The family includes the protease PfpI Q51732. This domain is also found in transcriptional regulators such as Q9RJG8; DJ-1/PfpI family protein 1157595 9795313 AARI_10360 Arthrobacter arilaitensis Re117 DJ-1/PfpI family protein YP_003916224.1 1156849 R 861360 CDS YP_003916225.1 308176819 9795317 1159258..1160355 1 NC_014550.1 match to protein domain PF00266: aminotransferase class-V. This domain is found in aminotransferases, and other enzymes, including cysteine desulphurase; aminotransferase 1160355 9795317 AARI_10400 Arthrobacter arilaitensis Re117 aminotransferase YP_003916225.1 1159258 D 861360 CDS YP_003916226.1 308176820 9795318 complement(1160448..1161464) 1 NC_014550.1 hypothetical protein 1161464 9795318 AARI_10410 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916226.1 1160448 R 861360 CDS YP_003916227.1 308176821 9795319 1161645..1162043 1 NC_014550.1 2 transmembrane helices predicted by TMHMM2.0; hypothetical protein 1162043 9795319 AARI_10420 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916227.1 1161645 D 861360 CDS YP_003916228.1 308176822 9795320 complement(1162113..1162514) 1 NC_014550.1 identified by match to PF00582: universal stress protein family. The universal stress protein UspA is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. UspA enhances the rate of cell survival during prolonged exposure to such conditions, and may provide a general stress endurance activity; universal stress family domain-containing protein 1162514 9795320 AARI_10430 Arthrobacter arilaitensis Re117 universal stress family domain-containing protein YP_003916228.1 1162113 R 861360 CDS YP_003916229.1 308176823 9795321 complement(1162511..1164124) 1 NC_014550.1 Tripartite Tricarboxylate Transporter (TTT) Family, tricarboxylate transporter (TC 2.A.80.1.1). Identified by similarity to protein SP:Q6M234 (Corynebacterium glutamicum). Component of the TctCBA citrate uptake system; citrate transport protein TctA 1164124 tctA 9795321 tctA Arthrobacter arilaitensis Re117 citrate transport protein TctA YP_003916229.1 1162511 R 861360 CDS YP_003916230.1 308176824 9794428 complement(1164146..1164649) 1 NC_014550.1 possible TctB component of the TctCBA citrate uptake system (TC 2.A.1.1); citrate transport protein TctB 1164649 tctB 9794428 tctB Arthrobacter arilaitensis Re117 citrate transport protein TctB YP_003916230.1 1164146 R 861360 CDS YP_003916231.1 308176825 9794429 complement(1164646..1165659) 1 NC_014550.1 Tripartite Tricarboxylate Transporter (TTT) Family, tricarboxylate transporter (TC 2.A.80.1.1). Identified by similarity to protein SP:Q8NLW1 (Corynebacterium glutamicum). Component of the TctCBA citrate uptake system; citrate transport protein TctC 1165659 tctC 9794429 tctC Arthrobacter arilaitensis Re117 citrate transport protein TctC YP_003916231.1 1164646 R 861360 CDS YP_003916232.1 308176826 9794430 1165889..1167499 1 NC_014550.1 protein-histidine kinases are key elements in two- component signal transduction systems, which enable bacteria to sense, respond, and adapt to a wide range of environments, stressors, and growth conditions; signal transduction histidine kinase 1167499 9794430 AARI_10470 Arthrobacter arilaitensis Re117 signal transduction histidine kinase YP_003916232.1 1165889 D 861360 CDS YP_003916233.1 308176827 9795322 1167510..1168184 1 NC_014550.1 response regulators are key elements in two- component signal transduction systems, which enable bacteria to sense, respond, and adapt to a wide range of environments, stressors, and growth conditions; two-component system response regulator 1168184 9795322 AARI_10480 Arthrobacter arilaitensis Re117 two-component system response regulator YP_003916233.1 1167510 D 861360 CDS YP_003916234.1 308176828 9795323 complement(1168269..1169663) 1 NC_014550.1 identified by match to protein family PF00743. Flavin-containing monooxygenase is a broad spectrum monooxygenase that accepts substrates as diverse as hydrazines, phosphines, boron-containing compounds, sulfides, selenides, iodide, as well as primary, secondary and tertiary amines. Generally converts nucleophilic heteroatom-containing chemicals and drugs into harmless, readily excreted metabolites; flavin-containing monooxygenase 1169663 9795323 AARI_10490 Arthrobacter arilaitensis Re117 flavin-containing monooxygenase YP_003916234.1 1168269 R 861360 CDS YP_003916235.1 308176829 9795324 complement(1170180..1171040) 1 NC_014550.1 catalyzes the decarboxylation of prephenate into phenylpyruvate. Involved in phenylalanine biosynthesis; prephenate dehydratase 1171040 9795324 AARI_10500 Arthrobacter arilaitensis Re117 prephenate dehydratase YP_003916235.1 1170180 R 861360 CDS YP_003916236.1 308176830 9795325 1171231..1171974 1 NC_014550.1 identified by match to PF09339: IclR helix-turn- helix domain and PF01614. This family of bacterial transcriptional regulators groups several proteins, including gylR, a possible activator protein for the gylABX glycerol operon in Streptomyces, and iclR, the repressor of the acetate operon (also known as glyoxylate bypass operon) in Escherichia coli and Salmonella typhimurium; IclR family transcriptional regulator 1171974 9795325 AARI_10510 Arthrobacter arilaitensis Re117 IclR family transcriptional regulator YP_003916236.1 1171231 D 861360 CDS YP_003916237.1 308176831 9795326 1172041..1173015 1 NC_014550.1 also named branched-chain alpha-keto acid dehydrogenase E1 component alpha chain. The branched-chain alpha-keto dehydrogenase complex catalyzes the oxidative decarboxylation of 4-methyl-2-oxopentanoate, 3-methyl-2- oxopentanoate and 3-methyl-2-oxobutanoate (branched chain 2-oxo acids derived from the transamination of leucine, valine and isoleucine). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2; EC 2.3. 1.168) and lipoamide dehydrogenase (E3; EC1.8.1.4). The E1 component is composed of alpha and beta chains; 2-oxoisovalerate dehydrogenase subunit alpha 1173015 9795326 AARI_10520 Arthrobacter arilaitensis Re117 2-oxoisovalerate dehydrogenase subunit alpha YP_003916237.1 1172041 D 861360 CDS YP_003916238.1 308176832 9795327 1173033..1174058 1 NC_014550.1 also named branched-chain alpha-keto acid dehydrogenase E1 component beta chain. The branched-chain alpha-keto dehydrogenase complex catalyzes the oxidative decarboxylation of 4-methyl-2-oxopentanoate, 3-methyl-2- oxopentanoate and 3-methyl-2-oxobutanoate (branched chain 2-oxo acids derived from the transamination of leucine, valine and isoleucine). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2; EC 2.3. 1.168) and lipoamide dehydrogenase (E3; EC1.8.1.4). The E1 component is composed of alpha and beta chains; 2-oxoisovalerate dehydrogenase subunit beta 1174058 9795327 AARI_10530 Arthrobacter arilaitensis Re117 2-oxoisovalerate dehydrogenase subunit beta YP_003916238.1 1173033 D 861360 CDS YP_003916239.1 308176833 9795328 1174055..1174288 1 NC_014550.1 possible lipoamide acyltransferase or N-terminal section of lipoamide acyltransferase (lipoyl-binding site). The branched-chain alpha-keto dehydrogenase complex catalyzes the oxidative decarboxylation of 4-methyl-2- oxopentanoate, 3-methyl-2-oxopentanoate and 3-methyl-2- oxobutanoate (branched chain 2-oxo acids derived from the transamination of leucine, valine and isoleucine). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2; EC 2.3.1.168) and lipoamide dehydrogenase (E3; EC1.8.1.4). The E1 component is composed of alpha and beta chains; lipoamide acyltransferase 1174288 9795328 AARI_10540 Arthrobacter arilaitensis Re117 lipoamide acyltransferase YP_003916239.1 1174055 D 861360 CDS YP_003916240.1 308176834 9795329 complement(1174413..1175423) 1 NC_014550.1 possibly involved in the metabolism of lipids. Match to protein family PF01370: NAD dependent epimerase/dehydratase family. This family of proteins utilise NAD as a cofactor. The proteins in this family use nucleotide-sugar substrates for a variety of chemical reactions; NAD dependent epimerase/dehydratase family protein 1175423 9795329 AARI_10550 Arthrobacter arilaitensis Re117 NAD dependent epimerase/dehydratase family protein YP_003916240.1 1174413 R 861360 CDS YP_003916241.1 308176835 9795330 complement(1175420..1178008) 1 NC_014550.1 match to protein family PF00501. This family of enzymes includes luciferase, long chain fatty acid Co-A ligase, acetyl-CoA synthetase and various other closely- related synthetases; fatty acid Co-A ligase 1178008 9795330 AARI_10560 Arthrobacter arilaitensis Re117 fatty acid Co-A ligase YP_003916241.1 1175420 R 861360 CDS YP_003916242.1 308176836 9795331 complement(1178005..1179030) 1 NC_014550.1 catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; beta-ketoacyl-ACP synthase III 1179030 fabH 9795331 fabH Arthrobacter arilaitensis Re117 beta-ketoacyl-ACP synthase III YP_003916242.1 1178005 R 861360 CDS YP_003916243.1 308176837 9795332 complement(1181069..1181197) 1 NC_014550.1 hypothetical protein 1181197 9795332 AARI_10590 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916243.1 1181069 R 861360 CDS YP_003916244.1 308176838 9795333 1181595..1182569 1 NC_014550.1 ADP-ribosylglycohydrolase 1182569 9795333 AARI_10600 Arthrobacter arilaitensis Re117 ADP-ribosylglycohydrolase YP_003916244.1 1181595 D 861360 CDS YP_003916245.1 308176839 9795334 complement(1182592..1182903) 1 NC_014550.1 hypothetical protein 1182903 9795334 AARI_10610 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916245.1 1182592 R 861360 CDS YP_003916246.1 308176840 9795335 1183248..1183841 1 NC_014550.1 3 transmembrane helices predicted by TMHMM2.0; hypothetical protein 1183841 9795335 AARI_10620 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916246.1 1183248 D 861360 CDS YP_003916247.1 308176841 9795336 complement(1183933..1184976) 1 NC_014550.1 catalyses the following reaction: an alcohol + NAD(+) <=> an aldehyde or ketone + NADH; Zn-dependent alcohol dehydrogenase 1184976 9795336 AARI_10630 Arthrobacter arilaitensis Re117 Zn-dependent alcohol dehydrogenase YP_003916247.1 1183933 R 861360 CDS YP_003916248.1 308176842 9795337 complement(1185279..1186529) 1 NC_014550.1 1 transmembrane helice predicted by TMHMM2.0; hypothetical protein 1186529 9795337 AARI_10640 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916248.1 1185279 R 861360 CDS YP_003916249.1 308176843 9795338 complement(1186629..1187342) 1 NC_014550.1 signal peptide predicted by SignalP 3.0 HMM (probability: 1.000) with cleavage site probability 0.351 between position 44 and 45; hypothetical protein 1187342 9795338 AARI_10650 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916249.1 1186629 R 861360 CDS YP_003916250.1 308176844 9795339 1188017..1190254 1 NC_014550.1 bifunctional enzyme, with a phosphorolytic 3 to 5 exoribonuclease activity and a 3 -terminal oligonucleotide polymerase activity. It is involved in mRNA processing and degradation; polyribonucleotide nucleotidyltransferase 1190254 pnp 9795339 pnp Arthrobacter arilaitensis Re117 polyribonucleotide nucleotidyltransferase YP_003916250.1 1188017 D 861360 CDS YP_003916251.1 308176845 9794210 complement(1190327..1191598) 1 NC_014550.1 4 transmembrane helices predicted by TMHMM2.0; hypothetical protein 1191598 9794210 AARI_10670 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916251.1 1190327 R 861360 CDS YP_003916252.1 308176846 9795343 complement(1193448..1194008) 1 NC_014550.1 purine nucleoside phosphorylase 1194008 9795343 AARI_10710 Arthrobacter arilaitensis Re117 purine nucleoside phosphorylase YP_003916252.1 1193448 R 861360 CDS YP_003916253.1 308176847 9795344 1194129..1194620 1 NC_014550.1 takes part in the activated methyl cycle, by salvaging the homocysteine moiety from the cycle intermediate S-D-ribosyl-L-homocysteine. As a by-product of this reaction, 4,5-dihydroxy-2,3-pentanedione is formed, which is the precursor of the autoinducer AI-2, a signal molecule, which may be used by a variety of bacteria for communication among and between species; S-ribosylhomocysteine lyase 1194620 luxS 9795344 luxS Arthrobacter arilaitensis Re117 S-ribosylhomocysteine lyase YP_003916253.1 1194129 D 861360 CDS YP_003916254.1 308176848 9794048 1194759..1195142 1 NC_014550.1 signal peptide predicted by SignalP 3.0 HMM (probability: 0.977) with cleavage site probability 0.233 between position 29 and 30; hypothetical protein 1195142 9794048 AARI_10730 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916254.1 1194759 D 861360 CDS YP_003916255.1 308176849 9795345 1195318..1196688 1 NC_014550.1 identified by match to PF05193 and PF00675. These metallopeptidases belong to MEROPS peptidase family M16 (clan ME). They also include proteins, which are classified as non-peptidase homologues either have been found experimentally to be without peptidase activity, or lack amino acid residues that are believed to be essential for the catalytic activity; peptidase M16 1196688 9795345 AARI_10740 Arthrobacter arilaitensis Re117 peptidase M16 YP_003916255.1 1195318 D 861360 CDS YP_003916256.1 308176850 9795346 complement(1196759..1197493) 1 NC_014550.1 match to PF00561: alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes; hydrolase 1197493 9795346 AARI_10750 Arthrobacter arilaitensis Re117 hydrolase YP_003916256.1 1196759 R 861360 CDS YP_003916257.1 308176851 9795347 complement(1197583..1197993) 1 NC_014550.1 signal peptide predicted by SignalP 3.0 HMM (probability: 1.000) with cleavage site probability 0.769 between position 35 and 36; hypothetical protein 1197993 9795347 AARI_10760 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916257.1 1197583 R 861360 CDS YP_003916258.1 308176852 9795348 1198189..1198947 1 NC_014550.1 catalyzes the second step in the biosynthesis of diaminopimelic acid and lysine, the NAD or NADP-dependent reduction of 2,3-dihydrodipicolinate into 2,3,4,5- tetrahydrodipicolinate; dihydrodipicolinate reductase 1198947 dapB 9795348 dapB Arthrobacter arilaitensis Re117 dihydrodipicolinate reductase YP_003916258.1 1198189 D 861360 CDS YP_003916259.1 308176853 9793789 1198944..1199399 1 NC_014550.1 identified by match to PF07719. The tetratrico peptide repeat (TPR) is a structural motif present in a wide range of proteins. It mediates protein-protein interactions and the assembly of multiprotein complexes. TPR motifs have been identified in various different organisms, ranging from bacteria to humans. Proteins containing TPRs are involved in a variety of biological processes, such as cell cycle regulation, transcriptional control, mitochondrial and peroxisomal protein transport, neurogenesis and protein folding; tetratrico peptide repeat-containing protein 1199399 9793789 AARI_10780 Arthrobacter arilaitensis Re117 tetratrico peptide repeat-containing protein YP_003916259.1 1198944 D 861360 CDS YP_003916260.1 308176854 9795349 complement(1199454..1200695) 1 NC_014550.1 10 transmembrane helices predicted by TMHMM2.0; hypothetical protein 1200695 9795349 AARI_10790 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916260.1 1199454 R 861360 CDS YP_003916261.1 308176855 9795350 1200694..1201605 1 NC_014550.1 catalyses the condensation of aspartate semialdehyde and pyruvate, the first reaction specific to the biosynthesis of lysine and of diaminopimelate; dihydrodipicolinate synthase 1201605 dapA 9795350 dapA Arthrobacter arilaitensis Re117 dihydrodipicolinate synthase YP_003916261.1 1200694 D 861360 CDS YP_003916262.1 308176856 9793788 1201625..1203331 1 NC_014550.1 identified by match to PF00753 (metallo-beta- lactamase superfamily) and PF07521 (RNA-metabolising metallo-beta-lactamase motif); RNA-metabolising metallo-beta-lactamase 1203331 9793788 AARI_10810 Arthrobacter arilaitensis Re117 RNA-metabolising metallo-beta-lactamase YP_003916262.1 1201625 D 861360 CDS YP_003916263.1 308176857 9795351 complement(1203412..1203642) 1 NC_014550.1 hypothetical protein 1203642 9795351 AARI_10820 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916263.1 1203412 R 861360 CDS YP_003916264.1 308176858 9795352 1203863..1204690 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, quaternary amine uptake transporter (QAT) family (TC 3.A.1. 12.z). ABCISSE: ABC transporter, ATP-binding protein (ABC), OTCN-family (osmoprotectants, taurine, cyanate and nitrate). Part of an uptake system of osmoprotrectants such as glycine betaine, carnitine, choline, proline betaine and L-proline; osmoprotectant (glycine betaine/carnitine/choline/L-proline) ABC transporter ATP-binding subunit 1204690 9795352 AARI_10830 Arthrobacter arilaitensis Re117 osmoprotectant (glycine betaine/carnitine/choline/L-proline) ABC transporter ATP-binding subunit YP_003916264.1 1203863 D 861360 CDS YP_003916265.1 308176859 9795353 1204699..1205373 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, quaternary amine uptake transporter (QAT) family (TC 3.A.1. 12.z). ABCISSE: ABC transporter, permease (IM), OTCN- family (osmoprotectants, taurine, cyanate and nitrate). Part of an uptake system of osmoprotrectants such as glycine betaine, carnitine, choline, proline betaine and L- proline; osmoprotectant (glycine betaine/carnitine/choline/L-proline) ABC transporter inner membrane subunit 1205373 9795353 AARI_10840 Arthrobacter arilaitensis Re117 osmoprotectant (glycine betaine/carnitine/choline/L-proline) ABC transporter inner membrane subunit YP_003916265.1 1204699 D 861360 CDS YP_003916266.1 308176860 9795354 1205370..1206101 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, quaternary amine uptake transporter (QAT) family (TC 3.A.1. 12.z). ABCISSE: ABC transporter, permease (IM), OTCN- family (osmoprotectants, taurine, cyanate and nitrate). Part of an uptake system of osmoprotrectants such as glycine betaine, carnitine, choline, proline betaine and L- proline; osmoprotectant (glycine betaine/carnitine/choline/L-proline) ABC transporter inner membrane subunit 1206101 9795354 AARI_10850 Arthrobacter arilaitensis Re117 osmoprotectant (glycine betaine/carnitine/choline/L-proline) ABC transporter inner membrane subunit YP_003916266.1 1205370 D 861360 CDS YP_003916267.1 308176861 9795355 1206098..1207000 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, quaternary amine uptake transporter (QAT) family (TC 3.A.1. 12.z). ABCISSE: ABC transporter, binding protein (BP), OTCN-family (osmoprotectants, taurine, cyanate and nitrate). Part of an uptake system of osmoprotrectants such as glycine betaine, carnitine, choline, proline betaine and L-proline; osmoprotectant (glycine betaine/carnitine/choline/L-proline) ABC transporter substrate-binding protein 1207000 9795355 AARI_10860 Arthrobacter arilaitensis Re117 osmoprotectant (glycine betaine/carnitine/choline/L-proline) ABC transporter substrate-binding protein YP_003916267.1 1206098 D 861360 CDS YP_003916268.1 308176862 9795356 1207239..1208258 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, iron chelate uptake transporter (FeCT) family (TC 3.A.1.14.z). ABCISSE: ABC transporter, binding protein (BP), ISVH- family (iron siderophores, vitamin B12 and hemin); iron-siderophore ABC transporter substrate-binding protein 1208258 9795356 AARI_10870 Arthrobacter arilaitensis Re117 iron-siderophore ABC transporter substrate-binding protein YP_003916268.1 1207239 D 861360 CDS YP_003916269.1 308176863 9795357 1208366..1209163 1 NC_014550.1 hypothetical protein 1209163 9795357 AARI_10880 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916269.1 1208366 D 861360 CDS YP_003916270.1 308176864 9795358 1209156..1209992 1 NC_014550.1 hypothetical protein 1209992 9795358 AARI_10890 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916270.1 1209156 D 861360 CDS YP_003916271.1 308176865 9795359 1209996..1211291 1 NC_014550.1 hypothetical protein 1211291 9795359 AARI_10900 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916271.1 1209996 D 861360 CDS YP_003916272.1 308176866 9795360 1211288..1212550 1 NC_014550.1 major facilitator superfamily (TC 2.A.1.y.z). Identified by match to protein family PF07690 (Major Facilitator Superfamily); MFS superfamily transporter 1212550 9795360 AARI_10910 Arthrobacter arilaitensis Re117 MFS superfamily transporter YP_003916272.1 1211288 D 861360 CDS YP_003916273.1 308176867 9795361 1212547..1213653 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, iron chelate uptake transporter (FeCT) family (TC 3.A.1.14.z). ABCISSE: ABC transporter, permease (IM), ISVH-family (iron siderophores, vitamin B12 and hemin); iron-siderophore ABC transporter inner membrane subunit 1213653 9795361 AARI_10920 Arthrobacter arilaitensis Re117 iron-siderophore ABC transporter inner membrane subunit YP_003916273.1 1212547 D 861360 CDS YP_003916274.1 308176868 9795362 1213684..1214469 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, iron chelate uptake transporter (FeCT) family (TC 3.A.1.14.z). ABCISSE: ABC transporter, ATP-binding protein (ABC), ISVH- family (iron siderophores, vitamin B12 and hemin); iron-siderophore ABC transporter ATP-binding subunit 1214469 9795362 AARI_10930 Arthrobacter arilaitensis Re117 iron-siderophore ABC transporter ATP-binding subunit YP_003916274.1 1213684 D 861360 CDS YP_003916275.1 308176869 9795363 1214557..1215960 1 NC_014550.1 E3 component of pyruvate dehydrogenase and 2- oxoglutarate dehydrogenase complexes; dihydrolipoyl dehydrogenase 1215960 lpdA 9795363 lpdA Arthrobacter arilaitensis Re117 dihydrolipoyl dehydrogenase YP_003916275.1 1214557 D 861360 CDS YP_003916276.1 308176870 9794043 1216015..1216500 1 NC_014550.1 4 transmembrane helices predicted by TMHMM2.0; hypothetical protein 1216500 9794043 AARI_10950 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916276.1 1216015 D 861360 CDS YP_003916277.1 308176871 9795364 1216860..1219841 1 NC_014550.1 DNA motor protein, which is both required to move DNA out of the region of the septum during cell division and for the septum formation. Tracks DNA in an ATP- dependent manner by generating positive supercoils in front of it and negative supercoils behind it; DNA translocase FtsK 1219841 ftsK 9795364 ftsK Arthrobacter arilaitensis Re117 DNA translocase FtsK YP_003916277.1 1216860 D 861360 CDS YP_003916278.1 308176872 9793866 1219847..1220449 1 NC_014550.1 involved in phospholipid biosynthesis; CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 1220449 pgsA 9793866 pgsA Arthrobacter arilaitensis Re117 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase YP_003916278.1 1219847 D 861360 CDS YP_003916279.1 308176873 9794201 1220460..1220942 1 NC_014550.1 match to protein family PF02464: competence-damaged protein. CinA is the first gene in the competence- inducible (cin) operon, and is thought to be specifically required at some stage in the process of transformation; CinA-like protein 1220942 9794201 AARI_10980 Arthrobacter arilaitensis Re117 CinA-like protein YP_003916279.1 1220460 D 861360 CDS YP_003916280.1 308176874 9795365 1221232..1221552 1 NC_014550.1 match to PF01381: helix-turn-helix. This is large family of DNA binding helix-turn helix proteins that include a bacterial plasmid copy control protein, bacterial methylases, various bacteriophage transcription control proteins and a vegetative specific protein from Dictyostelium discoideum (Slime mould); hypothetical protein 1221552 9795365 AARI_10990 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916280.1 1221232 D 861360 CDS YP_003916281.1 308176875 9795366 1221663..1221887 1 NC_014550.1 hypothetical protein 1221887 9795366 AARI_11000 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916281.1 1221663 D 861360 CDS YP_003916282.1 308176876 9795367 1222129..1223181 1 NC_014550.1 RecA is a DNA-dependent ATPase and functions in DNA repair systems. RecA protein catalyses an ATP-dependent DNA strand-exchange reaction that is the central step in the repair of dsDNA breaks by homologous recombination; RecA bacterial DNA recombination protein 1223181 recA 9795367 recA Arthrobacter arilaitensis Re117 RecA bacterial DNA recombination protein YP_003916282.1 1222129 D 861360 CDS YP_003916283.1 308176877 9794286 1223181..1224068 1 NC_014550.1 RecX is a bacterial regulatory protein. The gene encoding RecX is found downstream of recA, and is thought to interact with the RecA protein; regulatory protein RecX 1224068 recX 9794286 recX Arthrobacter arilaitensis Re117 regulatory protein RecX YP_003916283.1 1223181 D 861360 CDS YP_003916284.1 308176878 9794292 1224546..1226075 1 NC_014550.1 the MiaB enzyme is responsible for the modification of the isopentenylated adenine-37 base of most bacterial and eukaryotic tRNAs that read codons beginning with uracil. Adenine-37 is next to the anticodon on the 3 side in these tRNAs, and lack of modification at this site leads to an increased spontaneous mutation frequency; tRNA-i(6)A37 thiotransferase enzyme MiaB 1226075 miaB 9794292 miaB Arthrobacter arilaitensis Re117 tRNA-i(6)A37 thiotransferase enzyme MiaB YP_003916284.1 1224546 D 861360 CDS YP_003916285.1 308176879 9794082 1226080..1226982 1 NC_014550.1 tRNA isopentenyltransferase 1226982 miaA 9794082 miaA Arthrobacter arilaitensis Re117 tRNA isopentenyltransferase YP_003916285.1 1226080 D 861360 CDS YP_003916286.1 308176880 9794081 1227015..1227950 1 NC_014550.1 catalyzes the isomerization of L,L- to D,L-meso- diaminopimelate in the biosynthetic pathway leading from aspartate to lysine; diaminopimelate epimerase 1227950 dapF 9794081 dapF Arthrobacter arilaitensis Re117 diaminopimelate epimerase YP_003916286.1 1227015 D 861360 CDS YP_003916287.1 308176881 9793793 1228107..1228406 1 NC_014550.1 hypothetical protein 1228406 9793793 AARI_11060 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916287.1 1228107 D 861360 CDS YP_003916288.1 308176882 9795368 1228417..1228716 1 NC_014550.1 hypothetical protein 1228716 9795368 AARI_11070 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916288.1 1228417 D 861360 CDS YP_003916289.1 308176883 9795369 complement(1229257..1230612) 1 NC_014550.1 transposase of ISAar28, IS481 family 1230612 9795369 AARI_34790 Arthrobacter arilaitensis Re117 transposase of ISAar28, IS481 family YP_003916289.1 1229257 R 861360 CDS YP_003916290.1 308176884 9793421 1230848..1231909 1 NC_014550.1 hypothetical protein 1231909 9793421 AARI_11080 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916290.1 1230848 D 861360 CDS YP_003916291.1 308176885 9795370 complement(1231963..1232568) 1 NC_014550.1 match to protein domain PF05175. This domain is found in ribosomal RNA small subunit methyltransferase C as well as other methyltransferases; methyltransferase 1232568 9795370 AARI_11090 Arthrobacter arilaitensis Re117 methyltransferase YP_003916291.1 1231963 R 861360 CDS YP_003916292.1 308176886 9795371 1232894..1234555 1 NC_014550.1 identified by match to protein family PF01926; GTPase 1234555 9795371 AARI_11100 Arthrobacter arilaitensis Re117 GTPase YP_003916292.1 1232894 D 861360 CDS YP_003916293.1 308176887 9795372 1234548..1236542 1 NC_014550.1 possible DNA or RNA helicase; ATP-dependent helicase 1236542 9795372 AARI_11110 Arthrobacter arilaitensis Re117 ATP-dependent helicase YP_003916293.1 1234548 D 861360 CDS YP_003916294.1 308176888 9795373 1236681..1237736 1 NC_014550.1 glycosyl hydrolase 1237736 9795373 AARI_11120 Arthrobacter arilaitensis Re117 glycosyl hydrolase YP_003916294.1 1236681 D 861360 CDS YP_003916295.1 308176889 9795374 complement(1237793..1238512) 1 NC_014550.1 LexA represses around 20 genes of the cellular SOS response to DNA damage in Escherichia coli. In the presence of single-stranded DNA, the recA protein interacts with lexA causing an autocatalytic cleavage which disrupts the DNA- binding part of lexA, leading to derepression of the SOS regulon and eventually DNA repair; LexA repressor 1238512 lexA 9795374 lexA Arthrobacter arilaitensis Re117 LexA repressor YP_003916295.1 1237793 R 861360 CDS YP_003916296.1 308176890 9794036 1238771..1239124 1 NC_014550.1 match to protein domain PF01476. This domain is about 40 residues long and is found in a variety of enzymes involved in bacterial cell wall degradation. It may have a general peptidoglycan binding function; LysM domain-containing protein 1239124 9794036 AARI_11140 Arthrobacter arilaitensis Re117 LysM domain-containing protein YP_003916296.1 1238771 D 861360 CDS YP_003916297.1 308176891 9795375 1239206..1240312 1 NC_014550.1 catalyzes the the transfer of an amino group from 3- (imidazol-4-yl)-2-oxopropyl phosphate to glutamic acid to form histidinol phosphate and 2-oxoglutarate. Involved in histidine biosynthesis; histidinol-phosphate transaminase 1240312 hisC 9795375 hisC Arthrobacter arilaitensis Re117 histidinol-phosphate transaminase YP_003916297.1 1239206 D 861360 CDS YP_003916298.1 308176892 9793962 1240335..1240955 1 NC_014550.1 catalyzes the following reaction: D-erythro-1- (imidazol-4-yl)glycerol 3-phosphate <=> 3-(imidazol-4-yl)- 2-oxopropyl phosphate + H(2)O. Involved in histidine biosynthesis; imidazoleglycerol-phosphate dehydratase 1240955 hisB 9793962 hisB Arthrobacter arilaitensis Re117 imidazoleglycerol-phosphate dehydratase YP_003916298.1 1240335 D 861360 CDS YP_003916299.1 308176893 9793961 1240956..1241591 1 NC_014550.1 imidazole glycerol phosphate synthase converts N1- (5-phosphoribulosyl)-formimino-5-aminoimidazole-4- carboxamide ribonucleotide (PRFAR) to imidazole glycerol phosphate (ImGP) and 5-(5-aminoimidazole-4-carboxamide) ribonucleotide (AICAR). Involved in histidine biosynthesis; imidazole glycerol phosphate synthase, glutamine amidotransferase subunit 1241591 hisH 9793961 hisH Arthrobacter arilaitensis Re117 imidazole glycerol phosphate synthase, glutamine amidotransferase subunit YP_003916299.1 1240956 D 861360 CDS YP_003916300.1 308176894 9793967 1241594..1241743 1 NC_014550.1 hypothetical protein 1241743 9793967 AARI_11180 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916300.1 1241594 D 861360 CDS YP_003916301.1 308176895 9795376 1241771..1242508 1 NC_014550.1 catalyses the following reaction: 1-(5- phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide <=> 5-((5-phospho-1-deoxyribulos-1- ylamino)methylideneamino)- 1-(5-phosphoribosyl)imidazole-4- carboxamide. Involved in histidine biosynthesis; 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase 1242508 hisA 9795376 hisA Arthrobacter arilaitensis Re117 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase YP_003916301.1 1241771 D 861360 CDS YP_003916302.1 308176896 9793960 1242732..1243613 1 NC_014550.1 hypothetical protein 1243613 9793960 AARI_11200 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916302.1 1242732 D 861360 CDS YP_003916303.1 308176897 9795377 1243655..1244992 1 NC_014550.1 major facilitator superfamily (TC 2.A.1.y.z). Identified by match to protein family PF07690 (Major Facilitator Superfamily); MFS superfamily transporter 1244992 9795377 AARI_11210 Arthrobacter arilaitensis Re117 MFS superfamily transporter YP_003916303.1 1243655 D 861360 CDS YP_003916304.1 308176898 9795378 complement(1244989..1245540) 1 NC_014550.1 identified by match to PF00583: acetyltransferase (GNAT) family; GNAT family acetyltransferase 1245540 9795378 AARI_11220 Arthrobacter arilaitensis Re117 GNAT family acetyltransferase YP_003916304.1 1244989 R 861360 CDS YP_003916305.1 308176899 9795379 complement(1245638..1246003) 1 NC_014550.1 hypothetical protein 1246003 9795379 AARI_11230 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916305.1 1245638 R 861360 CDS YP_003916306.1 308176900 9795380 1246334..1246984 1 NC_014550.1 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins; translation initiation factor IF-3 1246984 infC 9795380 infC Arthrobacter arilaitensis Re117 translation initiation factor IF-3 YP_003916306.1 1246334 D 861360 CDS YP_003916307.1 308176901 9794010 1247151..1247345 1 NC_014550.1 L35 is a basic protein of 60 to 70 amino-acid residues from the large (50S) subunit; 50S ribosomal protein L35 1247345 rpmI 9794010 rpmI Arthrobacter arilaitensis Re117 50S ribosomal protein L35 YP_003916307.1 1247151 D 861360 CDS YP_003916308.1 308176902 9794340 1247450..1248097 1 NC_014550.1 binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit; 50S ribosomal protein L20 1248097 rplT 9794340 rplT Arthrobacter arilaitensis Re117 50S ribosomal protein L20 YP_003916308.1 1247450 D 861360 CDS YP_003916309.1 308176903 9794327 1248209..1249087 1 NC_014550.1 identified by match to protein family PF00588: SpoU rRNA Methylase family. Possible role in rRNA modification; RNA methyltransferase 1249087 9794327 AARI_11270 Arthrobacter arilaitensis Re117 RNA methyltransferase YP_003916309.1 1248209 D 861360 CDS YP_003916310.1 308176904 9795381 1249113..1249553 1 NC_014550.1 identified by match to PF00293. Members of the Nudix hydrolase superfamily catalyze the hydrolysis of nucleoside diphosphates linked to other moieties. Substrates of nudix hydrolases include intact and oxidatively damaged nucleoside triphosphates, dinucleoside polyphosphates, nucleotide-sugars and dinucleotide enzymes. These substrates are metabolites or cell signaling molecules that require regulation during different stages of the cell cycle or during periods of stress. In general, the role of the nudix hydrolase is to sanitize the nucleotide pools and to maintain cell viability, thereby serving as surveillance and house- cleaning enzymes; NUDIX hydrolase 1249553 9795381 AARI_11280 Arthrobacter arilaitensis Re117 NUDIX hydrolase YP_003916310.1 1249113 D 861360 CDS YP_003916311.1 308176905 9795382 1249640..1250269 1 NC_014550.1 signal peptide predicted by SignalP 3.0 HMM (probability: 0.878) with cleavage site probability 0.809 between position 28 and 29. 1 transmembrane helice predicted by TMHMM2.0 after the signal peptide; hypothetical protein 1250269 9795382 AARI_11290 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916311.1 1249640 D 861360 CDS YP_003916312.1 308176906 9795383 1250412..1251491 1 NC_014550.1 activates phenylalanine and transfers it to tRNA(Phe) as the first step in protein biosynthesis; phenylalanine--tRNA ligase subunit alpha 1251491 pheS 9795383 pheS Arthrobacter arilaitensis Re117 phenylalanine--tRNA ligase subunit alpha YP_003916312.1 1250412 D 861360 CDS YP_003916313.1 308176907 9794204 1251495..1254038 1 NC_014550.1 activates phenylalanine and transfers it to tRNA(Phe) as the first step in protein biosynthesis; phenylalanine--tRNA ligase subunit beta 1254038 pheT 9794204 pheT Arthrobacter arilaitensis Re117 phenylalanine--tRNA ligase subunit beta YP_003916313.1 1251495 D 861360 CDS YP_003916314.1 308176908 9794205 1254173..1254400 1 NC_014550.1 hypothetical protein 1254400 9794205 AARI_11320 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916314.1 1254173 D 861360 CDS YP_003916315.1 308176909 9795384 complement(1254397..1254882) 1 NC_014550.1 identified by match to PF00583: acetyltransferase (GNAT) family; GNAT family acetyltransferase 1254882 9795384 AARI_11330 Arthrobacter arilaitensis Re117 GNAT family acetyltransferase YP_003916315.1 1254397 R 861360 CDS YP_003916316.1 308176910 9795385 complement(1254964..1255245) 1 NC_014550.1 hypothetical protein 1255245 9795385 AARI_11340 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916316.1 1254964 R 861360 CDS YP_003916317.1 308176911 9795386 1255361..1255834 1 NC_014550.1 identified by match to PF00583: acetyltransferase (GNAT) family; GNAT family acetyltransferase 1255834 9795386 AARI_11350 Arthrobacter arilaitensis Re117 GNAT family acetyltransferase YP_003916317.1 1255361 D 861360 CDS YP_003916318.1 308176912 9795387 complement(1255895..1256416) 1 NC_014550.1 match to protein domain PF00156. This family includes a range of diverse phosphoribosyl transferase enzymes; phosphoribosyl transferase 1256416 9795387 AARI_11360 Arthrobacter arilaitensis Re117 phosphoribosyl transferase YP_003916318.1 1255895 R 861360 CDS YP_003916319.1 308176913 9795388 1256711..1258225 1 NC_014550.1 signal peptide predicted by SignalP 3.0 HMM (probability: 1.000) with cleavage site probability 0.971 between position 30 and 31. 1 transmembrane helice predicted by TMHMM2.0 after the signal peptide; hypothetical protein 1258225 9795388 AARI_11370 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916319.1 1256711 D 861360 CDS YP_003916320.1 308176914 9795389 1258267..1258905 1 NC_014550.1 identified by match to PF01648: 4- phosphopantetheinyl transferase superfamily. Holo-[acyl- carrier-protein] synthase catalyses the following reaction: CoA-(4-phosphopantetheine) + apo-[acyl-carrier- protein] => adenosine 3,5-bisphosphate + holo-[acyl- carrier-protein]. All polyketide synthases, fatty-acid synthases and non-ribosomal peptide synthases require post- translational modification of their constituent acyl- carrier-protein (ACP) domains to become catalytically active. The inactive apo-proteins are converted into their active holo-forms by transfer of the 4-phosphopantetheinyl moiety of CoA to the sidechain hydroxy group of a conserved serine residue in each ACP domain; holo-ACP synthase 1258905 9795389 AARI_11380 Arthrobacter arilaitensis Re117 holo-ACP synthase YP_003916320.1 1258267 D 861360 CDS YP_003916321.1 308176915 9795390 complement(1258929..1259825) 1 NC_014550.1 identified by match to protein domain PF03976. This domain is about 230 amino acids in length and has polyphosphate kinase activity; polyphosphate kinase domain-containing protein 1259825 9795390 AARI_11390 Arthrobacter arilaitensis Re117 polyphosphate kinase domain-containing protein YP_003916321.1 1258929 R 861360 CDS YP_003916322.1 308176916 9795391 complement(1259958..1261259) 1 NC_014550.1 identified by match to protein family PF01433. This group of metallopeptidases belong to the MEROPS peptidase family M1 (clan MA(E)). Members of this family are aminopeptidases. The members differ widely in specificity, hydrolysing acidic, basic or neutral N-terminal residues. Match to PS00142 pattern: neutral zinc metallopeptidases, zinc-binding region signature; aminopeptidase M1 1261259 9795391 AARI_11400 Arthrobacter arilaitensis Re117 aminopeptidase M1 YP_003916322.1 1259958 R 861360 CDS YP_003916323.1 308176917 9795392 complement(1261273..1265208) 1 NC_014550.1 match to protein domains TIGR02353 and TIGR01733. May be involved in enterobactin-like siderophore biosynthesis; non-ribosomal peptide synthetase component 1265208 9795392 AARI_11410 Arthrobacter arilaitensis Re117 non-ribosomal peptide synthetase component YP_003916323.1 1261273 R 861360 CDS YP_003916324.1 308176918 9795393 complement(1265373..1266293) 1 NC_014550.1 identified by match to protein family PF04909; amidohydrolase 1266293 9795393 AARI_11420 Arthrobacter arilaitensis Re117 amidohydrolase YP_003916324.1 1265373 R 861360 CDS YP_003916325.1 308176919 9795394 complement(1266296..1267264) 1 NC_014550.1 NADPH:quinone reductase catalyzes the following reaction: NADPH + quinone <=> NADP(+) + semiquinone. Quinone or similar compounds may act as acceptor; NADPH:quinone reductase 1267264 qor 9795394 qor Arthrobacter arilaitensis Re117 NADPH:quinone reductase YP_003916325.1 1266296 R 861360 CDS YP_003916326.1 308176920 9794279 1267448..1268479 1 NC_014550.1 catalyzes the third step in the biosynthesis of arginine from glutamate, the NADP-dependent reduction of N- acetyl-5-glutamyl phosphate into N-acetylglutamate 5- semialdehyde; N-acetyl-gamma-glutamyl-phosphate reductase 1268479 argC 9794279 argC Arthrobacter arilaitensis Re117 N-acetyl-gamma-glutamyl-phosphate reductase YP_003916326.1 1267448 D 861360 CDS YP_003916327.1 308176921 9793673 1268476..1269690 1 NC_014550.1 glutamate N-acetyltransferase (EC 2.3.1.35) catalyses the production of L-ornithine and N-acetyl-L- glutamate from N(2)-acetyl-L-ornithine and L-glutamate. Amino-acid N-acetyltransferase (EC 2.3.1.1) catalyses the formation of N-acetyl-L-glutamate from acetyl-CoA and L- glutamate. Involved in arginine biosynthesis; bifunctional glutamate N-acetyltransferase/amino-acid N-acetyltransferase protein 1269690 argJ 9793673 argJ Arthrobacter arilaitensis Re117 bifunctional glutamate N-acetyltransferase/amino-acid N-acetyltransferase protein YP_003916327.1 1268476 D 861360 CDS YP_003916328.1 308176922 9793679 1269712..1270665 1 NC_014550.1 catalyses the formation of N-acetyl-L-glutamate 5- phosphate from N-acetyl-L-glutamate. Involved in arginine biosynthesis; acetylglutamate kinase 1270665 argB 9793679 argB Arthrobacter arilaitensis Re117 acetylglutamate kinase YP_003916328.1 1269712 D 861360 CDS YP_003916329.1 308176923 9793672 1270665..1271930 1 NC_014550.1 catalyses the following reaction: N(2)-acetyl-L- ornithine + 2-oxoglutarate <=> N-acetyl-L-glutamate 5- semialdehyde + L-glutamate. Involved in arginine biosynthesis; acetylornithine transaminase 1271930 argD 9793672 argD Arthrobacter arilaitensis Re117 acetylornithine transaminase YP_003916329.1 1270665 D 861360 CDS YP_003916330.1 308176924 9793674 1271981..1272940 1 NC_014550.1 catalyzes the conversion of ornithine and carbamoyl phosphate to citrulline. It is involved in the biosynthesis of arginine and, in some bacteria, it is also involved in the degradation of arginine (the arginine deaminase pathway); ornithine carbamoyltransferase 1272940 argF 9793674 argF Arthrobacter arilaitensis Re117 ornithine carbamoyltransferase YP_003916330.1 1271981 D 861360 CDS YP_003916331.1 308176925 9793676 1272942..1273445 1 NC_014550.1 regulates arginine biosynthesis when complexed with arginine by binding at site that overlap the promotors of the arginine biosynthesis genes; arginine repressor 1273445 argR 9793676 argR Arthrobacter arilaitensis Re117 arginine repressor YP_003916331.1 1272942 D 861360 CDS YP_003916332.1 308176926 9793680 1273542..1275440 1 NC_014550.1 identified by match to PF01844; HNH endonuclease domain-containing protein 1275440 9793680 AARI_11500 Arthrobacter arilaitensis Re117 HNH endonuclease domain-containing protein YP_003916332.1 1273542 D 861360 CDS YP_003916333.1 308176927 9795395 complement(1275565..1276131) 1 NC_014550.1 match to protein domain PF01661. This domain is an ADP-ribose binding module. It is found in a number of otherwise unrelated proteins; macro domain-containing protein 1276131 9795395 AARI_11510 Arthrobacter arilaitensis Re117 macro domain-containing protein YP_003916333.1 1275565 R 861360 CDS YP_003916334.1 308176928 9795396 1276386..1277801 1 NC_014550.1 catalyzes the formation of arginine and fumarate from argininosuccinate, the last step in the biosynthesis of arginine; argininosuccinate lyase 1277801 argH 9795396 argH Arthrobacter arilaitensis Re117 argininosuccinate lyase YP_003916334.1 1276386 D 861360 CDS YP_003916335.1 308176929 9793678 1277918..1278658 1 NC_014550.1 hypothetical protein 1278658 9793678 AARI_11530 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916335.1 1277918 D 861360 CDS YP_003916336.1 308176930 9795397 1278755..1279303 1 NC_014550.1 catalyses the formation of AMP and diphosphate from adenine and 5-phospho-alpha-D-ribose 1-diphosphate. Involved in purine salvage; adenine phosphoribosyltransferase 1279303 apt 9795397 apt Arthrobacter arilaitensis Re117 adenine phosphoribosyltransferase YP_003916336.1 1278755 D 861360 CDS YP_003916337.1 308176931 9793668 1279544..1281823 1 NC_014550.1 match to protein family PS51198: UvrD-like DNA helicase ATP-binding domain profile. UvrD-like DNA helicases belong to superfamily 1 (SF1); ATP-dependent DNA helicase 1281823 9793668 AARI_11550 Arthrobacter arilaitensis Re117 ATP-dependent DNA helicase YP_003916337.1 1279544 D 861360 CDS YP_003916338.1 308176932 9795398 1282025..1283350 1 NC_014550.1 activates tyrosine and transfers it to tRNA(Tyr) as the first step in protein biosynthesis; tyrosine--tRNA ligase 1283350 tyrS 9795398 tyrS Arthrobacter arilaitensis Re117 tyrosine--tRNA ligase YP_003916338.1 1282025 D 861360 CDS YP_003916339.1 308176933 9793607 1289641..1290840 1 NC_014550.1 transposase of ISAar5, IS256 family 1290840 9793607 AARI_34800 Arthrobacter arilaitensis Re117 transposase of ISAar5, IS256 family YP_003916339.1 1289641 D 861360 CDS YP_003916340.1 308176934 9793422 1291158..1293482 1 NC_014550.1 hypothetical protein 1293482 9793422 AARI_11570 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916340.1 1291158 D 861360 CDS YP_003916341.1 308176935 9795399 1293531..1294538 1 NC_014550.1 identified by match to PF00702. This family includes L-2-haloacid dehalogenase, epoxide hydrolases and phosphatases; haloacid dehalogenase 1294538 9795399 AARI_11580 Arthrobacter arilaitensis Re117 haloacid dehalogenase YP_003916341.1 1293531 D 861360 CDS YP_003916342.1 308176936 9795400 1294541..1294714 1 NC_014550.1 hypothetical protein 1294714 9795400 AARI_11590 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916342.1 1294541 D 861360 CDS YP_003916343.1 308176937 9795401 1294711..1295499 1 NC_014550.1 identified by similarity to protein SP:Q50760 (Mycobacterium tuberculosis); haemolysin 1295499 9795401 AARI_11600 Arthrobacter arilaitensis Re117 haemolysin YP_003916343.1 1294711 D 861360 CDS YP_003916344.1 308176938 9795402 1295518..1296600 1 NC_014550.1 catalyses the phosphorylation of NAD to NADP utilising ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus; NAD(+) kinase 1296600 ppnK 9795402 ppnK Arthrobacter arilaitensis Re117 NAD(+) kinase YP_003916344.1 1295518 D 861360 CDS YP_003916345.1 308176939 9794219 1296718..1298472 1 NC_014550.1 RecN is thought to be involved in recombinational repair of damaged DNA; DNA repair protein RecN 1298472 recN 9794219 recN Arthrobacter arilaitensis Re117 DNA repair protein RecN YP_003916345.1 1296718 D 861360 CDS YP_003916346.1 308176940 9794289 1298580..1300259 1 NC_014550.1 catalyzes the ATP-dependent formation of CTP from UTP and glutamine; CTP synthase 1300259 pyrG 9794289 pyrG Arthrobacter arilaitensis Re117 CTP synthase YP_003916346.1 1298580 D 861360 CDS YP_003916347.1 308176941 9794272 1300374..1301018 1 NC_014550.1 identified by match to PF00293. Members of the Nudix hydrolase superfamily catalyze the hydrolysis of nucleoside diphosphates linked to other moieties. Substrates of nudix hydrolases include intact and oxidatively damaged nucleoside triphosphates, dinucleoside polyphosphates, nucleotide-sugars and dinucleotide enzymes. These substrates are metabolites or cell signaling molecules that require regulation during different stages of the cell cycle or during periods of stress. In general, the role of the nudix hydrolase is to sanitize the nucleotide pools and to maintain cell viability, thereby serving as surveillance and house- cleaning enzymes; NUDIX hydrolase 1301018 9794272 AARI_11640 Arthrobacter arilaitensis Re117 NUDIX hydrolase YP_003916347.1 1300374 D 861360 CDS YP_003916348.1 308176942 9795403 1301015..1301938 1 NC_014550.1 site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids; tyrosine recombinase subunit XerD 1301938 xerD 9795403 xerD Arthrobacter arilaitensis Re117 tyrosine recombinase subunit XerD YP_003916348.1 1301015 D 861360 CDS YP_003916349.1 308176943 9794508 1301941..1302441 1 NC_014550.1 identified by match to PF00293. Members of the Nudix hydrolase superfamily catalyze the hydrolysis of nucleoside diphosphates linked to other moieties. Substrates of nudix hydrolases include intact and oxidatively damaged nucleoside triphosphates, dinucleoside polyphosphates, nucleotide-sugars and dinucleotide enzymes. These substrates are metabolites or cell signaling molecules that require regulation during different stages of the cell cycle or during periods of stress. In general, the role of the nudix hydrolase is to sanitize the nucleotide pools and to maintain cell viability, thereby serving as surveillance and house- cleaning enzymes; NUDIX hydrolase 1302441 9794508 AARI_11660 Arthrobacter arilaitensis Re117 NUDIX hydrolase YP_003916349.1 1301941 D 861360 CDS YP_003916350.1 308176944 9795404 complement(1302456..1302668) 1 NC_014550.1 match to PF01381: helix-turn-helix. This is large family of DNA binding helix-turn helix proteins that include a bacterial plasmid copy control protein, bacterial methylases, various bacteriophage transcription control proteins and a vegetative specific protein from Dictyostelium discoideum (Slime mould); hypothetical protein 1302668 9795404 AARI_11670 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916350.1 1302456 R 861360 CDS YP_003916351.1 308176945 9795405 complement(1302668..1303171) 1 NC_014550.1 signal peptide predicted by SignalP 3.0 HMM (probability: 0.981) with cleavage site probability 0.558 between position 27 and 28. 3 transmembrane helices predicted by TMHMM2.0 after the signal peptide; hypothetical protein 1303171 9795405 AARI_11680 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916351.1 1302668 R 861360 CDS YP_003916352.1 308176946 9795406 complement(1303300..1304439) 1 NC_014550.1 2-methylcitrate synthase catalyses the conversion of oxaloacetate and propanoyl-CoA into (2R,3S)-2- hydroxybutane-1,2,3-tricarboxylate and coenzyme A. The enzyme acts on acetyl-CoA, propanoyl-CoA, butanoyl-CoA and pentanoyl-CoA. Involved in the metabolism of propionate; 2-methylcitrate synthase 1304439 prpC 9795406 prpC Arthrobacter arilaitensis Re117 2-methylcitrate synthase YP_003916352.1 1303300 R 861360 CDS YP_003916353.1 308176947 9794231 complement(1304534..1305463) 1 NC_014550.1 catalyses the formation of pyruvate and succinate from (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate. Involved in the metabolism of propionate; methylisocitrate lyase 1305463 prpB 9794231 prpB Arthrobacter arilaitensis Re117 methylisocitrate lyase YP_003916353.1 1304534 R 861360 CDS YP_003916354.1 308176948 9794230 complement(1305465..1306982) 1 NC_014550.1 involved in the metabolism of propionate; 2-methylcitrate dehydratase 1306982 prpD 9794230 prpD Arthrobacter arilaitensis Re117 2-methylcitrate dehydratase YP_003916354.1 1305465 R 861360 CDS YP_003916355.1 308176949 9794232 complement(1306979..1307632) 1 NC_014550.1 identified by match to protein family PF00392. This family of regulatory proteins consists of the N-terminal HTH region of GntR-like bacterial transcription factors. At the C-terminus there is usually an effector- binding/oligomerisation domain. The GntR-like proteins can be divided into six sub-families: MocR, YtrR, FadR, AraR, HutC and PlmA. Many of these proteins have been shown experimentally to be autoregulatory, enabling the prediction of operator sites and the discovery of cis/trans relationships; GntR family transcriptional regulator 1307632 9794232 AARI_11720 Arthrobacter arilaitensis Re117 GntR family transcriptional regulator YP_003916355.1 1306979 R 861360 CDS YP_003916356.1 308176950 9795407 1307820..1309736 1 NC_014550.1 catalyzes the synthesis of propionyl-CoA from propionate and CoA; propionate--CoA ligase 1309736 prpE 9795407 prpE Arthrobacter arilaitensis Re117 propionate--CoA ligase YP_003916356.1 1307820 D 861360 CDS YP_003916357.1 308176951 9794233 complement(1309762..1310511) 1 NC_014550.1 response regulators are key elements in two- component signal transduction systems, which enable bacteria to sense, respond, and adapt to a wide range of environments, stressors, and growth conditions; two-component system response regulator 1310511 9794233 AARI_11740 Arthrobacter arilaitensis Re117 two-component system response regulator YP_003916357.1 1309762 R 861360 CDS YP_003916358.1 308176952 9795408 complement(1310527..1312164) 1 NC_014550.1 protein-histidine kinases are key elements in two- component signal transduction systems, which enable bacteria to sense, respond, and adapt to a wide range of environments, stressors, and growth conditions; signal transduction histidine kinase 1312164 9795408 AARI_11750 Arthrobacter arilaitensis Re117 signal transduction histidine kinase YP_003916358.1 1310527 R 861360 CDS YP_003916359.1 308176953 9795409 1312340..1313638 1 NC_014550.1 identified by similarity to protein SP:Q8NMH8 (Corynebacterium glutamicum). Dicarboxylate/Amino Acid:Cation (Na+ or H+) symporter (DAACS) family, C4- dicarboxylate transporter (substrates: fumarate, D- and L- malate, succinate, succinamide, orotate, iticonate, mesaconate) (TC 2.A.23.1.3); C4-dicarboxylate transporter 1313638 dctA 9795409 dctA Arthrobacter arilaitensis Re117 C4-dicarboxylate transporter YP_003916359.1 1312340 D 861360 CDS YP_003916360.1 308176954 9793796 1313767..1314390 1 NC_014550.1 identified by match to protein family PF00657; GDSL-like lipase/esterase 1314390 9793796 AARI_11770 Arthrobacter arilaitensis Re117 GDSL-like lipase/esterase YP_003916360.1 1313767 D 861360 CDS YP_003916361.1 308176955 9795411 complement(1314847..1315197) 1 NC_014550.1 identified by match to PF00903: glyoxalase/bleomycin resistance protein/dioxygenase superfamily; glyoxalase family protein 1315197 9795411 AARI_11790 Arthrobacter arilaitensis Re117 glyoxalase family protein YP_003916361.1 1314847 R 861360 CDS YP_003916362.1 308176956 9795414 complement(1315923..1316321) 1 NC_014550.1 hypothetical protein 1316321 9795414 AARI_11820 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916362.1 1315923 R 861360 CDS YP_003916363.1 308176957 9795415 1316490..1317386 1 NC_014550.1 identified by match to protein family PF01656. chromosome partitioning protein; ParA family protein 1317386 9795415 AARI_11830 Arthrobacter arilaitensis Re117 ParA family protein YP_003916363.1 1316490 D 861360 CDS YP_003916364.1 308176958 9795416 1317386..1318288 1 NC_014550.1 identified by match to protein family PF02616. ScpA participates in chromosomal partition during cell division. Component of a cohesin-like complex composed of scpA, scpB and smc; chromosome segregation and condensation protein A 1318288 scpA 9795416 scpA Arthrobacter arilaitensis Re117 chromosome segregation and condensation protein A YP_003916364.1 1317386 D 861360 CDS YP_003916365.1 308176959 9794378 1318281..1318871 1 NC_014550.1 identified by match to protein family PIRSF019345. ScpB participates in chromosomal partition during cell division. Component of a cohesin-like complex composed of scpA, scpB and smc; chromosome segregation and condensation protein B 1318871 scpB 9794378 scpB Arthrobacter arilaitensis Re117 chromosome segregation and condensation protein B YP_003916365.1 1318281 D 861360 CDS YP_003916366.1 308176960 9794379 1318973..1320094 1 NC_014550.1 identified by match to protein family PF00849. Pseudouridylate synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5- ribosyluracil, psi); pseudouridylate synthase 1320094 9794379 AARI_11860 Arthrobacter arilaitensis Re117 pseudouridylate synthase YP_003916366.1 1318973 D 861360 CDS YP_003916367.1 308176961 9795417 1320098..1321198 1 NC_014550.1 catalyses the following reaction: prephenate + NAD(+) <=> 4-hydroxyphenylpyruvate + CO(2) + NADH. Involved in tyrosine biosynthesis; prephenate dehydrogenase 1321198 tyrA 9795417 tyrA Arthrobacter arilaitensis Re117 prephenate dehydrogenase YP_003916367.1 1320098 D 861360 CDS YP_003916368.1 308176962 9794485 1321195..1321875 1 NC_014550.1 catalyzes the transfer of a phosphate group from ATP to either CMP or UMP to form CDP or UDP and ADP; cytidylate kinase 1321875 cmk 9794485 cmk Arthrobacter arilaitensis Re117 cytidylate kinase YP_003916368.1 1321195 D 861360 CDS YP_003916369.1 308176963 9793745 1321941..1323473 1 NC_014550.1 possible role in ribosome assembly and stability; GTP-binding protein EngA 1323473 engA 9793745 engA Arthrobacter arilaitensis Re117 GTP-binding protein EngA YP_003916369.1 1321941 D 861360 CDS YP_003916370.1 308176964 9793608 1323749..1324591 1 NC_014550.1 identified by match to protein family PF02567. PhzC/PhzF is involved in dimerisation of two 2, 3-dihydro-3- oxo-anthranilic acid molecules to create phenazine-1- carboxylic acid (PCA) by P. fluorescens. This family also contains a thymidilate synthase from Mycobacterium tuberculosis. Many phenazine compounds are found in nature and are produced by bacteria such as Pseudomonas spp., Streptomyces spp., and Pantoea agglomerans. These compounds have been implicated in the virulence and competitive fitness of producing organisms. For example, the phenazine pyocyanin produced by Pseudomonas aeruginosa contributes to its ability to colonise the lungs of cystic fibrosis patients. Similarly, phenazine-1-carboxylic acid, produced by a number of Pseudomonas, increases survival in soil environments and has been shown to be essential for the biological control activity of certain strains; phenazine biosynthesis protein PhzC/PhzF 1324591 9793608 AARI_11900 Arthrobacter arilaitensis Re117 phenazine biosynthesis protein PhzC/PhzF YP_003916370.1 1323749 D 861360 CDS YP_003916371.1 308176965 9795418 1324801..1326507 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, () drug resistance ATPase-2 (Drug RA2) family (TC 3.A.1.121.z). ABCISSE: fused ATP-binding protein (ABC2), ART-family, ARE-subfamily (antibiotic resistance); drug resistance ATP-binding protein 1326507 9795418 AARI_11910 Arthrobacter arilaitensis Re117 drug resistance ATP-binding protein YP_003916371.1 1324801 D 861360 CDS YP_003916372.1 308176966 9795419 1326750..1328639 1 NC_014550.1 phenol 2-monooxygenase catalyzes the following reaction: Phenol + NADPH + O(2) => catechol + NADP(+) + H(2)O. Also active with resorcinol and o-cresol; phenol 2-monooxygenase 1328639 9795419 AARI_11920 Arthrobacter arilaitensis Re117 phenol 2-monooxygenase YP_003916372.1 1326750 D 861360 CDS YP_003916373.1 308176967 9795420 complement(1328879..1329241) 1 NC_014550.1 hypothetical protein 1329241 9795420 AARI_11930 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916373.1 1328879 R 861360 CDS YP_003916374.1 308176968 9795421 1329509..1329961 1 NC_014550.1 match to PF00498. The forkhead-associated (FHA) domain is a phosphopeptide recognition domain found in many regulatory proteins; FHA domain-containing protein 1329961 9795421 AARI_11940 Arthrobacter arilaitensis Re117 FHA domain-containing protein YP_003916374.1 1329509 D 861360 CDS YP_003916375.1 308176969 9795422 1330036..1330791 1 NC_014550.1 identified by match to PF00376. Members of the family include the mercuric resistance operon regulatory protein merR; Bacillus subtilis bltR and bmrR; Bacillus glnR; Streptomyces coelicolor hspR; Bradyrhizobium japonicum nolA; Escherichia coli superoxide response regulator soxR; and Streptomyces lividans transcriptional activator tipA; MerR family transcriptional regulator 1330791 9795422 AARI_11950 Arthrobacter arilaitensis Re117 MerR family transcriptional regulator YP_003916375.1 1330036 D 861360 CDS YP_003916376.1 308176970 9795423 1330832..1331314 1 NC_014550.1 hypothetical protein 1331314 9795423 AARI_11960 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916376.1 1330832 D 861360 CDS YP_003916377.1 308176971 9795424 1331556..1332149 1 NC_014550.1 members of the MerR-family include the mercuric resistance operon regulatory protein merR; Bacillus subtilis bltR and bmrR; Bacillus glnR; Streptomyces coelicolor hspR; Bradyrhizobium japonicum nolA; Escherichia coli superoxide response regulator soxR; and Streptomyces lividans transcriptional activator tipA; MerR family transcriptional regulator 1332149 9795424 AARI_11970 Arthrobacter arilaitensis Re117 MerR family transcriptional regulator YP_003916377.1 1331556 D 861360 CDS YP_003916378.1 308176972 9795425 complement(1332249..1333076) 1 NC_014550.1 identified by match to protein family PF01656. chromosome partitioning protein; ParA family protein 1333076 9795425 AARI_11980 Arthrobacter arilaitensis Re117 ParA family protein YP_003916378.1 1332249 R 861360 CDS YP_003916379.1 308176973 9795426 1333416..1336868 1 NC_014550.1 biotin-containing enzyme that catalyzes a two step carboxylation of pyruvate to oxaloacetate; pyruvate carboxylase 1336868 pyc 9795426 pyc Arthrobacter arilaitensis Re117 pyruvate carboxylase YP_003916379.1 1333416 D 861360 CDS YP_003916380.1 308176974 9794262 1336972..1337514 1 NC_014550.1 hypothetical protein 1337514 9794262 AARI_12000 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916380.1 1336972 D 861360 CDS YP_003916381.1 308176975 9795427 complement(1337487..1339298) 1 NC_014550.1 activates fatty acids by binding to coenzyme A. Possibly involved in the degradation of lipids via beta- oxidation; fatty-acid--CoA ligase 1339298 9795427 AARI_12010 Arthrobacter arilaitensis Re117 fatty-acid--CoA ligase YP_003916381.1 1337487 R 861360 CDS YP_003916382.1 308176976 9795428 complement(1339412..1339846) 1 NC_014550.1 2 transmembrane helices predicted by TMHMM2.0; hypothetical protein 1339846 9795428 AARI_12020 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916382.1 1339412 R 861360 CDS YP_003916383.1 308176977 9795429 complement(1339843..1340616) 1 NC_014550.1 match to protein family PIRSF017388; esterase/lipase 1340616 9795429 AARI_12030 Arthrobacter arilaitensis Re117 esterase/lipase YP_003916383.1 1339843 R 861360 CDS YP_003916384.1 308176978 9795430 1340750..1341421 1 NC_014550.1 1-acylglycerol-3-phosphate O-acyltransferase catalyzes the following reaction: Acyl-CoA + 1-acyl-sn- glycerol 3-phosphate <=> CoA + 1,2-diacyl-sn-glycerol 3- phosphate. It is involved in phospholipid biosynthesis; 1-acylglycerol-3-phosphate O-acyltransferase 1341421 9795430 AARI_12040 Arthrobacter arilaitensis Re117 1-acylglycerol-3-phosphate O-acyltransferase YP_003916384.1 1340750 D 861360 CDS YP_003916385.1 308176979 9795431 1341503..1342897 1 NC_014550.1 involved in phenylalanine, tyrosine and tryptophan biosynthesis; 3-deoxy-7-phosphoheptulonate synthase 1342897 aroG 9795431 aroG Arthrobacter arilaitensis Re117 3-deoxy-7-phosphoheptulonate synthase YP_003916385.1 1341503 D 861360 CDS YP_003916386.1 308176980 9793686 complement(1342969..1345185) 1 NC_014550.1 identified by match to protein domain PD000001. Match to PS00108 pattern. Protein kinases are a group of enzymes that possess a catalytic subunit which transfers the gamma phosphate from nucleotide triphosphates (often ATP) to one or more amino acid residues in a protein substrate side chain, resulting in a conformational change affecting protein function. They play a role in a mulititude of cellular processes, including division, proliferation, apoptosis, and differentiation; Ser/Thr protein kinase 1345185 9793686 AARI_12060 Arthrobacter arilaitensis Re117 Ser/Thr protein kinase YP_003916386.1 1342969 R 861360 CDS YP_003916387.1 308176981 9795432 complement(1345388..1345636) 1 NC_014550.1 identified by match to protein family PF02467. WhiB is a transcription factor in Actinobacteria, required for differentiation and sporulation; WhiB family transcriptional regulator 1345636 9795432 AARI_12070 Arthrobacter arilaitensis Re117 WhiB family transcriptional regulator YP_003916387.1 1345388 R 861360 CDS YP_003916388.1 308176982 9795433 1345994..1346407 1 NC_014550.1 4 transmembrane helices predicted by TMHMM2.0; hypothetical protein 1346407 9795433 AARI_12080 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916388.1 1345994 D 861360 CDS YP_003916389.1 308176983 9795434 complement(1346270..1350085) 1 NC_014550.1 match to PF01580. This domain is found extensively in a wide variety of proteins from prokaryotes and plasmids; FtsK/SpoIIIE domain-containing protein 1350085 9795434 AARI_12090 Arthrobacter arilaitensis Re117 FtsK/SpoIIIE domain-containing protein YP_003916389.1 1346270 R 861360 CDS YP_003916390.1 308176984 9795435 1350334..1351557 1 NC_014550.1 identified by match to protein domain PF00437; type II/IV secretion system protein E 1351557 9795435 AARI_12100 Arthrobacter arilaitensis Re117 type II/IV secretion system protein E YP_003916390.1 1350334 D 861360 CDS YP_003916391.1 308176985 9795436 1351560..1352411 1 NC_014550.1 identified by match to protein domain PF00482; type II secretion system protein F 1352411 9795436 AARI_12110 Arthrobacter arilaitensis Re117 type II secretion system protein F YP_003916391.1 1351560 D 861360 CDS YP_003916392.1 308176986 9795437 1352408..1353349 1 NC_014550.1 identified by match to protein domain PF00482; type II secretion system protein F 1353349 9795437 AARI_12120 Arthrobacter arilaitensis Re117 type II secretion system protein F YP_003916392.1 1352408 D 861360 CDS YP_003916393.1 308176987 9795438 1353412..1353645 1 NC_014550.1 1 transmembrane helice predicted by TMHMM2.0; hypothetical protein 1353645 9795438 AARI_12130 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916393.1 1353412 D 861360 CDS YP_003916394.1 308176988 9795439 1353691..1354071 1 NC_014550.1 identified by match to protein family PF07811. The members of this family are similar to a region of the protein product of the bacterial tadE locus. In various bacterial species, the tad locus is closely linked to flp- like genes, which encode proteins required for the production of pili involved in adherence to surfaces. It is thought that the tad loci encode proteins that act to assemble or export an Flp pilus in various bacteria; TadE-like family protein 1354071 9795439 AARI_12140 Arthrobacter arilaitensis Re117 TadE-like family protein YP_003916394.1 1353691 D 861360 CDS YP_003916395.1 308176989 9795440 1354025..1354510 1 NC_014550.1 1 transmembrane helice predicted by TMHMM2.0; hypothetical protein 1354510 9795440 AARI_12150 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916395.1 1354025 D 861360 CDS YP_003916396.1 308176990 9795441 1354560..1354958 1 NC_014550.1 signal peptide predicted by SignalP 3.0 HMM (probability: 0.997) with cleavage site probability 0.440 between position 27 and 28; hypothetical protein 1354958 9795441 AARI_12160 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916396.1 1354560 D 861360 CDS YP_003916397.1 308176991 9795442 1355226..1356341 1 NC_014550.1 directs the termination of translation in response to the peptide chain termination codons UGA and UAA; peptide chain release factor 2 1356341 prfB 9795442 prfB Arthrobacter arilaitensis Re117 peptide chain release factor 2 YP_003916397.1 1355226 D 861360 CDS YP_003916398.1 308176992 9794221 1356622..1357419 1 NC_014550.1 TCDB: general secretory pathway (Sec) family, general secretory pathway (Sec-SRP) complex (TC 3.A.5.1.1). ABCISSE: ATP-binding protein (ABC), CDI- family. CDI family systems are found only in eubacteria and are comprised of two proteins: the FtsE ATP-binding protein and the FtsX permease. It is possible that CDI systems play a role in the proper membrane targeting or insertion of some proteins essential for septum formation; cell division ATP-binding protein FtsE 1357419 ftsE 9794221 ftsE Arthrobacter arilaitensis Re117 cell division ATP-binding protein FtsE YP_003916398.1 1356622 D 861360 CDS YP_003916399.1 308176993 9793864 1357416..1358330 1 NC_014550.1 ABCISSE: IM (permease), CDI-family. CDI family systems are found only in eubacteria and are comprised of two proteins: the FtsE ATP-binding protein and the FtsX permease. It is possible that CDI systems play a role in the proper membrane targeting or insertion of some proteins essential for septum formation; cell division membrane protein FtsX 1358330 ftsX 9793864 ftsX Arthrobacter arilaitensis Re117 cell division membrane protein FtsX YP_003916399.1 1357416 D 861360 CDS YP_003916400.1 308176994 9793869 1358383..1359846 1 NC_014550.1 identified by match to protein family PF01551. Members of this family are zinc metallopeptidases with a range of specificities. Peptidase family M23 are also endopeptidases. Signal peptide predicted by SignalP 3.0 HMM (probability: 1.000) with cleavage site probability 1. 000 between position 32 and 33; peptidase M23 1359846 9793869 AARI_12200 Arthrobacter arilaitensis Re117 peptidase M23 YP_003916400.1 1358383 D 861360 CDS YP_003916401.1 308176995 9795443 1359901..1360380 1 NC_014550.1 in bacteria, SsrA RNA recognizes ribosomes stalled on defective messages and acts as a tRNA and mRNA to mediate the addition of a short peptide tag to the C- terminus of the partially synthesized nascent polypeptide chain. The SsrA-tagged protein is then degraded by C- terminal-specific proteases. SmpB binds specifically to the ssrA RNA and is required for stable association of ssrA with ribosomes; SsrA-binding protein 1360380 smpB 9795443 smpB Arthrobacter arilaitensis Re117 SsrA-binding protein YP_003916401.1 1359901 D 861360 CDS YP_003916402.1 308176996 9794398 1360987..1362117 1 NC_014550.1 match to protein family PF00589; phage integrase 1362117 9794398 AARI_12220 Arthrobacter arilaitensis Re117 phage integrase YP_003916402.1 1360987 D 861360 CDS YP_003916403.1 308176997 9795444 complement(1362176..1362703) 1 NC_014550.1 signal peptide predicted by SignalP 3.0 HMM (probability: 1.000) with cleavage site probability 0.718 between position 29 and 30; hypothetical protein 1362703 9795444 AARI_12230 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916403.1 1362176 R 861360 CDS YP_003916404.1 308176998 9793425 1364784..1365257 1 NC_014550.1 4 transmembrane helices predicted by TMHMM2.0; hypothetical protein 1365257 9793425 AARI_12240 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916404.1 1364784 D 861360 CDS YP_003916405.1 308176999 9795446 complement(1365306..1365686) 1 NC_014550.1 identified by match to protein family PF02537. CrcB is a integral membrane protein possibly involved in chromosome condensation. Overexpression in E. coli also leads to camphor resistance; CrcB-like protein 1365686 9795446 AARI_12250 Arthrobacter arilaitensis Re117 CrcB-like protein YP_003916405.1 1365306 R 861360 CDS YP_003916406.1 308177000 9795447 complement(1365686..1366147) 1 NC_014550.1 identified by match to protein family PF02537. CrcB is a integral membrane protein possibly involved in chromosome condensation. Overexpression in E. coli also leads to camphor resistance; CrcB-like protein 1366147 9795447 AARI_12260 Arthrobacter arilaitensis Re117 CrcB-like protein YP_003916406.1 1365686 R 861360 CDS YP_003916407.1 308177001 9795448 complement(1366159..1366638) 1 NC_014550.1 identified by match to PF00582: universal stress protein family. The universal stress protein UspA is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. UspA enhances the rate of cell survival during prolonged exposure to such conditions, and may provide a general stress endurance activity; universal stress family domain-containing protein 1366638 9795448 AARI_12270 Arthrobacter arilaitensis Re117 universal stress family domain-containing protein YP_003916407.1 1366159 R 861360 CDS YP_003916408.1 308177002 9795449 complement(1366710..1367339) 1 NC_014550.1 identified by match to PF01325 and PF02742. The diphtheria toxin repressor protein (DTXR) is a member of this group. In Corynebacterium diphtheriae where it has been studied in some detail this protein acts as an iron- binding repressor of dipheteria toxin gene expression and may serve as a global regulator of gene expression. The N- terminus may be involved in iron binding and may associate with the Tox operator. Binding of DTXR to Tox operator requires a divalent metal ion such as cobalt, ferric, manganese and nickel whereas zinc shows weak activation; metal-dependent transcriptional regulator 1367339 9795449 AARI_12280 Arthrobacter arilaitensis Re117 metal-dependent transcriptional regulator YP_003916408.1 1366710 R 861360 CDS YP_003916409.1 308177003 9795450 complement(1367352..1368158) 1 NC_014550.1 catalyses the following reaction: L-histidinol phosphate + H(2)O <=> L-histidinol + phosphate. Involved in histidine biosynthesis; histidinol-phosphatase 1368158 9795450 AARI_12290 Arthrobacter arilaitensis Re117 histidinol-phosphatase YP_003916409.1 1367352 R 861360 CDS YP_003916410.1 308177004 9795451 complement(1368174..1369265) 1 NC_014550.1 identified by match to protein family PF03193; ribosome-associated GTPase 1369265 9795451 AARI_12300 Arthrobacter arilaitensis Re117 ribosome-associated GTPase YP_003916410.1 1368174 R 861360 CDS YP_003916411.1 308177005 9795452 complement(1369265..1370668) 1 NC_014550.1 sixth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid. Chorismic acid is a important intermediate in the synthesis of aromatic compounds, such as aromatic amino acids (phenylalanine, tyrosine and tryptophan), p-aminobenzoic acid, folate and ubiquinone; 3-phosphoshikimate 1-carboxyvinyltransferase 1370668 aroA 9795452 aroA Arthrobacter arilaitensis Re117 3-phosphoshikimate 1-carboxyvinyltransferase YP_003916411.1 1369265 R 861360 CDS YP_003916412.1 308177006 9793682 1370727..1371530 1 NC_014550.1 the sigma factor RpoE is involved in heat shock and oxidative stress response; it is believed to control protein processing in the extracytoplasmic compartment; RNA polymerase sigma factor RpoE 1371530 rpoE 9793682 rpoE Arthrobacter arilaitensis Re117 RNA polymerase sigma factor RpoE YP_003916412.1 1370727 D 861360 CDS YP_003916413.1 308177007 9794346 1371532..1371792 1 NC_014550.1 may act on RpoE. Match to protein family TIGR02949. Anti-sigma factors bind to sigma factors and inhibit their transcriptional activity; anti-sigma factor 1371792 9794346 AARI_12330 Arthrobacter arilaitensis Re117 anti-sigma factor YP_003916413.1 1371532 D 861360 CDS YP_003916414.1 308177008 9795453 complement(1372039..1372728) 1 NC_014550.1 match to protein family SSF52266; lipase/esterase 1372728 9795453 AARI_12340 Arthrobacter arilaitensis Re117 lipase/esterase YP_003916414.1 1372039 R 861360 CDS YP_003916415.1 308177009 9795454 complement(1372861..1376613) 1 NC_014550.1 it is a component of the multienzyme 2-oxoglutarate dehydrogenase complex in which multiple copies of it are bound to a core of molecules of EC 2.3.1.61 (Dihydrolipoyllysine-residue succinyltransferase), which also binds multiple copies of EC 1.8.1.4 (Dihydrolipoyl dehydrogenase). Involved in the TCA cycle; oxoglutarate dehydrogenase (succinyl-transferring) 1376613 sucA 9795454 sucA Arthrobacter arilaitensis Re117 oxoglutarate dehydrogenase (succinyl-transferring) YP_003916415.1 1372861 R 861360 CDS YP_003916416.1 308177010 9794409 1377043..1378365 1 NC_014550.1 possible transporter. Match to PF00571 (CBS domain pair); CBS domain-containing transporter 1378365 9794409 AARI_12360 Arthrobacter arilaitensis Re117 CBS domain-containing transporter YP_003916416.1 1377043 D 861360 CDS YP_003916417.1 308177011 9795455 1378370..1379431 1 NC_014550.1 match to PF00571 (CBS domain pair); CBS domain-containing protein 1379431 9795455 AARI_12370 Arthrobacter arilaitensis Re117 CBS domain-containing protein YP_003916417.1 1378370 D 861360 CDS YP_003916418.1 308177012 9795456 1379562..1380395 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, Manganese/Zinc/Iron Chelate Uptake Transporter (MZT) Family (TC 3.A.1.15.z). ABCISSE: ABC transporter, ATP- binding protein (ABC), MET-family. This family is comprised of systems involved in the uptake of various metallic cations such as iron, manganese and zinc; iron/manganese/zinc ABC transporter ATP-binding subunit 1380395 9795456 AARI_12380 Arthrobacter arilaitensis Re117 iron/manganese/zinc ABC transporter ATP-binding subunit YP_003916418.1 1379562 D 861360 CDS YP_003916419.1 308177013 9795457 1380405..1381262 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, Manganese/Zinc/Iron Chelate Uptake Transporter (MZT) Family (TC 3.A.1.15.z). ABCISSE: ABC transporter, permease (IM), MET-family. This family is comprised of systems involved in the uptake of various metallic cations such as iron, manganese and zinc; iron/manganese/zinc ABC transporter inner membrane subunit 1381262 9795457 AARI_12390 Arthrobacter arilaitensis Re117 iron/manganese/zinc ABC transporter inner membrane subunit YP_003916419.1 1380405 D 861360 CDS YP_003916420.1 308177014 9795458 1381338..1381976 1 NC_014550.1 hypothetical protein 1381976 9795458 AARI_12400 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916420.1 1381338 D 861360 CDS YP_003916421.1 308177015 9795459 complement(1382044..1383504) 1 NC_014550.1 identified by match to SM00507; HNH endonuclease domain-containing protein 1383504 9795459 AARI_12410 Arthrobacter arilaitensis Re117 HNH endonuclease domain-containing protein YP_003916421.1 1382044 R 861360 CDS YP_003916422.1 308177016 9795460 complement(1383616..1384041) 1 NC_014550.1 match to protein family PF01475; metal uptake regulation protein 1384041 9795460 AARI_12420 Arthrobacter arilaitensis Re117 metal uptake regulation protein YP_003916422.1 1383616 R 861360 CDS YP_003916423.1 308177017 9795461 1384194..1384895 1 NC_014550.1 identified by match to PF00753: metallo-beta- lactamase superfamily. Apart from the beta-lactamases, a number of other proteins contain this domain. These proteins include thiolesterases, members of the glyoxalase II family, that catalyse the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid and a competence protein that is essential for natural transformation in Neisseria gonorrhoeae and could be a transporter involved in DNA uptake; metallo-beta-lactamase 1384895 9795461 AARI_12430 Arthrobacter arilaitensis Re117 metallo-beta-lactamase YP_003916423.1 1384194 D 861360 CDS YP_003916424.1 308177018 9795462 1384895..1385731 1 NC_014550.1 thiosulfate sulfurtransferase 1385731 9795462 AARI_12440 Arthrobacter arilaitensis Re117 thiosulfate sulfurtransferase YP_003916424.1 1384895 D 861360 CDS YP_003916425.1 308177019 9795463 1385761..1386189 1 NC_014550.1 match to PF01230: histidine triad motif. The histidine triad motif (HIT) is related to the sequence H- phi-H-phi-H-phi-phi (where phi is a hydrophobic amino acid). Proteins containing HIT domains form a superfamily of nucleotide hydrolases and transferases that act on the alpha-phosphate of ribonucleotides; histidine triad family protein 1386189 9795463 AARI_12450 Arthrobacter arilaitensis Re117 histidine triad family protein YP_003916425.1 1385761 D 861360 CDS YP_003916426.1 308177020 9795464 1386192..1386608 1 NC_014550.1 hypothetical protein 1386608 9795464 AARI_12460 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916426.1 1386192 D 861360 CDS YP_003916427.1 308177021 9795465 complement(1386583..1390542) 1 NC_014550.1 identified by similarity to protein SP:P43329 (Escherichia coli); ATP-dependent helicase HrpA 1390542 hrpA 9795465 hrpA Arthrobacter arilaitensis Re117 ATP-dependent helicase HrpA YP_003916427.1 1386583 R 861360 CDS YP_003916428.1 308177022 9793977 1390941..1391936 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, carbohydrate uptake transporter-2 (CUT2) family (TC 3.A.1. 2.z). ABCISSE: ABCISSE: ABC transporter, binding protein (BP), MOS-family (monosaccharides: pentoses and hexoses); sugar ABC transporter substrate-binding protein 1391936 9793977 AARI_12480 Arthrobacter arilaitensis Re117 sugar ABC transporter substrate-binding protein YP_003916428.1 1390941 D 861360 CDS YP_003916429.1 308177023 9795466 1392036..1392956 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, carbohydrate uptake transporter-2 (CUT2) family (TC 3.A.1. 2.z). ABCISSE: ABCISSE: ABC transporter, permease (IM), MOS-family (monosaccharides: pentoses and hexoses); sugar ABC transporter inner membrane subunit 1392956 9795466 AARI_12490 Arthrobacter arilaitensis Re117 sugar ABC transporter inner membrane subunit YP_003916429.1 1392036 D 861360 CDS YP_003916430.1 308177024 9795467 1392949..1393740 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily (TC 3. A.1.y.z). ABCISSE: ABC transporter, ATP-binding protein (ABC), NO family (NO family systems represent few ABC proteins with unknown function and which are apparently unrelated to existent families); sugar ABC transporter ATP-binding subunit 1393740 9795467 AARI_12500 Arthrobacter arilaitensis Re117 sugar ABC transporter ATP-binding subunit YP_003916430.1 1392949 D 861360 CDS YP_003916431.1 308177025 9795469 complement(1394688..1395167) 1 NC_014550.1 hypothetical protein 1395167 9795469 AARI_12520 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916431.1 1394688 R 861360 CDS YP_003916432.1 308177026 9795470 complement(1395348..1396544) 1 NC_014550.1 major facilitator superfamily (TC 2.A.1.y.z). Identified by match to protein family PF07690 (Major Facilitator Superfamily); MFS superfamily transporter 1396544 9795470 AARI_12530 Arthrobacter arilaitensis Re117 MFS superfamily transporter YP_003916432.1 1395348 R 861360 CDS YP_003916433.1 308177027 9795471 complement(1396681..1397034) 1 NC_014550.1 identified by match to PF00583: acetyltransferase (GNAT) family; GNAT family acetyltransferase 1397034 9795471 AARI_12540 Arthrobacter arilaitensis Re117 GNAT family acetyltransferase YP_003916433.1 1396681 R 861360 CDS YP_003916434.1 308177028 9795472 complement(1397180..1397683) 1 NC_014550.1 hypothetical protein 1397683 9795472 AARI_12550 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916434.1 1397180 R 861360 CDS YP_003916435.1 308177029 9795473 complement(1397781..1398503) 1 NC_014550.1 5 transmembrane helices predicted by TMHMM2.0; hypothetical protein 1398503 9795473 AARI_12560 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916435.1 1397781 R 861360 CDS YP_003916436.1 308177030 9793609 1398869..1400512 1 NC_014550.1 activates arginine and transfers it to tRNA(Arg) as the first step in protein biosynthesis; arginine--tRNA ligase 1400512 argS 9793609 argS Arthrobacter arilaitensis Re117 arginine--tRNA ligase YP_003916436.1 1398869 D 861360 CDS YP_003916437.1 308177031 9793681 1400519..1401940 1 NC_014550.1 catalyzes the conversion of diaminopimelic acid into lysine, the last step in the biosynthesis of lysine; diaminopimelate decarboxylase 1401940 lysA 9793681 lysA Arthrobacter arilaitensis Re117 diaminopimelate decarboxylase YP_003916437.1 1400519 D 861360 CDS YP_003916438.1 308177032 9794049 1401941..1403227 1 NC_014550.1 catalyzes NAD-dependent reduction of aspartate 4- semialdehyde into homoserine. This reaction is the third step in a pathway leading from aspartate to homoserine. The latter participates in the biosynthesis of threonine and then isoleucine as well as in that of methionine; homoserine dehydrogenase 1403227 thrA 9794049 thrA Arthrobacter arilaitensis Re117 homoserine dehydrogenase YP_003916438.1 1401941 D 861360 CDS YP_003916439.1 308177033 9794448 1403229..1404329 1 NC_014550.1 catalyzes the formation of threonine from homoserine-phosphate; threonine synthase 1404329 thrC 9794448 thrC Arthrobacter arilaitensis Re117 threonine synthase YP_003916439.1 1403229 D 861360 CDS YP_003916440.1 308177034 9794450 1404461..1405393 1 NC_014550.1 catalyses the formation of O-phospho-L-homoserine from homoserine. Involved in the biosynthesis of threonine; homoserine kinase 1405393 thrB 9794450 thrB Arthrobacter arilaitensis Re117 homoserine kinase YP_003916440.1 1404461 D 861360 CDS YP_003916441.1 308177035 9794449 1405728..1407995 1 NC_014550.1 facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho RNA-dependent ATPase activity, and release of the mRNA from the DNA template; transcription termination factor Rho 1407995 rho 9794449 rho Arthrobacter arilaitensis Re117 transcription termination factor Rho YP_003916441.1 1405728 D 861360 CDS YP_003916442.1 308177036 9794294 1408184..1409257 1 NC_014550.1 directs the termination of translation in response to the peptide chain termination codons UGA and UAA; peptide chain release factor 1 1409257 prfA 9794294 prfA Arthrobacter arilaitensis Re117 peptide chain release factor 1 YP_003916442.1 1408184 D 861360 CDS YP_003916443.1 308177037 9794220 1409265..1410122 1 NC_014550.1 HemK methylates the translation termination release factors RF1 and RF2, which plays a pivotal role in the termination of translation; methylase of peptide chain release factors 1410122 hemK 9794220 hemK Arthrobacter arilaitensis Re117 methylase of peptide chain release factors YP_003916443.1 1409265 D 861360 CDS YP_003916444.1 308177038 9793958 1410157..1410840 1 NC_014550.1 Sua5 family translation factor 1410840 9793958 AARI_12650 Arthrobacter arilaitensis Re117 Sua5 family translation factor YP_003916444.1 1410157 D 861360 CDS YP_003916445.1 308177039 9795475 1410837..1411958 1 NC_014550.1 match to protein family PF00953. Catalyzes the formation of undecaprenyl-pyrophosphoryl-N-acetylmuramoyl- pentapeptide from UDP-MurNAc-pentapeptide and undecaprenyl- phosphate. Involved in peptidoglycan biosynthesis; phospho-N-acetylmuramoyl-pentapeptide- transferase 1411958 9795475 AARI_12660 Arthrobacter arilaitensis Re117 phospho-N-acetylmuramoyl-pentapeptide- transferase YP_003916445.1 1410837 D 861360 CDS YP_003916446.1 308177040 9795476 1412128..1412562 1 NC_014550.1 4 transmembrane helices predicted by TMHMM2.0; hypothetical protein 1412562 9795476 AARI_12670 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916446.1 1412128 D 861360 CDS YP_003916447.1 308177041 9795477 1412828..1413640 1 NC_014550.1 H(+)-transporting two-sector ATPase (also named ATP synthase or ATPase) is composed of two linked complexes: the F1 ATPase complex is the catalytic core and is composed of 5 subunits (alpha, beta, gamma, delta, epsilon), while the F0 ATPase complex is the membrane- embedded proton channel that is composed of at least 3 subunits (A-C). It uses a proton gradient to drive ATP synthesis and hydrolyzes ATP to build the proton gradient; H(+)-transporting two-sector ATPase subunit A 1413640 atpB 9795477 atpB Arthrobacter arilaitensis Re117 H(+)-transporting two-sector ATPase subunit A YP_003916447.1 1412828 D 861360 CDS YP_003916448.1 308177042 9793700 1413748..1413960 1 NC_014550.1 H(+)-transporting two-sector ATPase (also named ATP synthase or ATPase) is composed of two linked complexes: the F1 ATPase complex is the catalytic core and is composed of 5 subunits (alpha, beta, gamma, delta, epsilon), while the F0 ATPase complex is the membrane- embedded proton channel that is composed of at least 3 subunits (A-C). It uses a proton gradient to drive ATP synthesis and hydrolyzes ATP to build the proton gradient; H(+)-transporting two-sector ATPase subunit C 1413960 atpE 9793700 atpE Arthrobacter arilaitensis Re117 H(+)-transporting two-sector ATPase subunit C YP_003916448.1 1413748 D 861360 CDS YP_003916449.1 308177043 9793703 1414041..1414595 1 NC_014550.1 H(+)-transporting two-sector ATPase (also named ATP synthase or ATPase) is composed of two linked complexes: the F1 ATPase complex is the catalytic core and is composed of 5 subunits (alpha, beta, gamma, delta, epsilon), while the F0 ATPase complex is the membrane- embedded proton channel that is composed of at least 3 subunits (A-C). It uses a proton gradient to drive ATP synthesis and hydrolyzes ATP to build the proton gradient; H(+)-transporting two-sector ATPase subunit B 1414595 atpF 9793703 atpF Arthrobacter arilaitensis Re117 H(+)-transporting two-sector ATPase subunit B YP_003916449.1 1414041 D 861360 CDS YP_003916450.1 308177044 9793704 1414595..1415407 1 NC_014550.1 H(+)-transporting two-sector ATPase (also named ATP synthase or ATPase) is composed of two linked complexes: the F1 ATPase complex is the catalytic core and is composed of 5 subunits (alpha, beta, gamma, delta, epsilon), while the F0 ATPase complex is the membrane- embedded proton channel that is composed of at least 3 subunits (A-C). It uses a proton gradient to drive ATP synthesis and hydrolyzes ATP to build the proton gradient; H(+)-transporting two-sector ATPase subunit delta 1415407 atpH 9793704 atpH Arthrobacter arilaitensis Re117 H(+)-transporting two-sector ATPase subunit delta YP_003916450.1 1414595 D 861360 CDS YP_003916451.1 308177045 9793706 1415534..1417171 1 NC_014550.1 H(+)-transporting two-sector ATPase (also named ATP synthase or ATPase) is composed of two linked complexes: the F1 ATPase complex is the catalytic core and is composed of 5 subunits (alpha, beta, gamma, delta, epsilon), while the F0 ATPase complex is the membrane- embedded proton channel that is composed of at least 3 subunits (A-C). It uses a proton gradient to drive ATP synthesis and hydrolyzes ATP to build the proton gradient; H(+)-transporting two-sector ATPase subunit alpha 1417171 atpA 9793706 atpA Arthrobacter arilaitensis Re117 H(+)-transporting two-sector ATPase subunit alpha YP_003916451.1 1415534 D 861360 CDS YP_003916452.1 308177046 9793699 1417247..1418140 1 NC_014550.1 H(+)-transporting two-sector ATPase (also named ATP synthase or ATPase) is composed of two linked complexes: the F1 ATPase complex is the catalytic core and is composed of 5 subunits (alpha, beta, gamma, delta, epsilon), while the F0 ATPase complex is the membrane- embedded proton channel that is composed of at least 3 subunits (A-C). It uses a proton gradient to drive ATP synthesis and hydrolyzes ATP to build the proton gradient; H(+)-transporting two-sector ATPase subunit gamma 1418140 atpG 9793699 atpG Arthrobacter arilaitensis Re117 H(+)-transporting two-sector ATPase subunit gamma YP_003916452.1 1417247 D 861360 CDS YP_003916453.1 308177047 9793705 1418177..1419622 1 NC_014550.1 H(+)-transporting two-sector ATPase (also named ATP synthase or ATPase) is composed of two linked complexes: the F1 ATPase complex is the catalytic core and is composed of 5 subunits (alpha, beta, gamma, delta, epsilon), while the F0 ATPase complex is the membrane- embedded proton channel that is composed of at least 3 subunits (A-C). It uses a proton gradient to drive ATP synthesis and hydrolyzes ATP to build the proton gradient; H(+)-transporting two-sector ATPase subunit beta 1419622 atpD 9793705 atpD Arthrobacter arilaitensis Re117 H(+)-transporting two-sector ATPase subunit beta YP_003916453.1 1418177 D 861360 CDS YP_003916454.1 308177048 9793702 1419625..1419894 1 NC_014550.1 H(+)-transporting two-sector ATPase (also named ATP synthase or ATPase) is composed of two linked complexes: the F1 ATPase complex is the catalytic core and is composed of 5 subunits (alpha, beta, gamma, delta, epsilon), while the F0 ATPase complex is the membrane- embedded proton channel that is composed of at least 3 subunits (A-C). It uses a proton gradient to drive ATP synthesis and hydrolyzes ATP to build the proton gradient; H(+)-transporting two-sector ATPase subunit epsilon 1419894 atpC 9793702 atpC Arthrobacter arilaitensis Re117 H(+)-transporting two-sector ATPase subunit epsilon YP_003916454.1 1419625 D 861360 CDS YP_003916455.1 308177049 9793701 1419903..1420331 1 NC_014550.1 1 transmembrane helice predicted by TMHMM2.0; hypothetical protein 1420331 9793701 AARI_12760 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916455.1 1419903 D 861360 CDS YP_003916456.1 308177050 9795478 1420473..1421594 1 NC_014550.1 identified by match to protein family PF01370: NAD dependent epimerase/dehydratase family. This family of proteins utilise NAD as a cofactor. The proteins in this family use nucleotide-sugar substrates for a variety of chemical reactions; NAD dependent epimerase/dehydratase family protein 1421594 9795478 AARI_12770 Arthrobacter arilaitensis Re117 NAD dependent epimerase/dehydratase family protein YP_003916456.1 1420473 D 861360 CDS YP_003916457.1 308177051 9795479 complement(1421458..1422666) 1 NC_014550.1 catalyzes the hydrolysis of N-acetylglucosamine-6- phosphate to glucosamine-6-phosphate and acetate; N-acetylglucosamine-6-phosphate deacetylase 1422666 nagA 9795479 nagA Arthrobacter arilaitensis Re117 N-acetylglucosamine-6-phosphate deacetylase YP_003916457.1 1421458 R 861360 CDS YP_003916458.1 308177052 9794131 complement(1422846..1423592) 1 NC_014550.1 1 transmembrane helice predicted by TMHMM2.0; hypothetical protein 1423592 9794131 AARI_12790 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916458.1 1422846 R 861360 CDS YP_003916459.1 308177053 9795480 complement(1423756..1424451) 1 NC_014550.1 hypothetical protein 1424451 9795480 AARI_12800 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916459.1 1423756 R 861360 CDS YP_003916460.1 308177054 9795481 1424511..1424882 1 NC_014550.1 hypothetical protein 1424882 9795481 AARI_12810 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916460.1 1424511 D 861360 CDS YP_003916461.1 308177055 9795482 complement(1424905..1426275) 1 NC_014550.1 9 transmembrane helices predicted by TMHMM2.0; hypothetical protein 1426275 9795482 AARI_12820 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916461.1 1424905 R 861360 CDS YP_003916462.1 308177056 9795483 1426455..1428167 1 NC_014550.1 2 transmembrane helices predicted by TMHMM2.0; hypothetical protein 1428167 9795483 AARI_12830 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916462.1 1426455 D 861360 CDS YP_003916463.1 308177057 9795484 1428173..1429084 1 NC_014550.1 thioredoxin 1429084 9795484 AARI_12840 Arthrobacter arilaitensis Re117 thioredoxin YP_003916463.1 1428173 D 861360 CDS YP_003916464.1 308177058 9795485 1429220..1429978 1 NC_014550.1 TC 3.A.1.y.z. ABCISSE: ABC transporter, ATP-binding protein (ABC), DRI-family, DRB-subfamily (drug resistance, ). Possible function in drug efflux; drug resistance ATP-binding protein 1429978 9795485 AARI_12850 Arthrobacter arilaitensis Re117 drug resistance ATP-binding protein YP_003916464.1 1429220 D 861360 CDS YP_003916465.1 308177059 9795486 1429960..1431525 1 NC_014550.1 TC 3.A.1.y.z. ABCISSE: ABC transporter, permease (IM), DRI-family, DRB-subfamily (drug resistance, ). Possible function in drug efflux; drug ABC transporter inner membrane subunit 1431525 9795486 AARI_12860 Arthrobacter arilaitensis Re117 drug ABC transporter inner membrane subunit YP_003916465.1 1429960 D 861360 CDS YP_003916466.1 308177060 9795487 1431827..1432078 1 NC_014550.1 hypothetical protein 1432078 9795487 AARI_12870 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916466.1 1431827 D 861360 CDS YP_003916467.1 308177061 9795488 1432134..1433900 1 NC_014550.1 possible DNA or RNA helicase; ATP-dependent helicase 1433900 9795488 AARI_12880 Arthrobacter arilaitensis Re117 ATP-dependent helicase YP_003916467.1 1432134 D 861360 CDS YP_003916468.1 308177062 9795489 complement(1434152..1434745) 1 NC_014550.1 nicotinamidase converts nicotinamide to nicotinic acid (niacin) and ammonia, which in turn can be recycled to make nicotinamide adenine dinucleotide (NAD); nicotinamidase 1434745 pncA 9795489 pncA Arthrobacter arilaitensis Re117 nicotinamidase YP_003916468.1 1434152 R 861360 CDS YP_003916469.1 308177063 9794208 complement(1434850..1436148) 1 NC_014550.1 nicotinate phosphoribosyltransferase catalyses the formation of nicotinate D-ribonucleotide and PPi from 5- phospho-alpha-D-ribose 1-diphosphate and nicotinic acid, this is the first, and also rate limiting, reaction in the NAD salvage synthesis. This salvage pathway serves to recycle NAD degradation products; nicotinate phosphoribosyltransferase 1436148 pncB 9794208 pncB Arthrobacter arilaitensis Re117 nicotinate phosphoribosyltransferase YP_003916469.1 1434850 R 861360 CDS YP_003916470.1 308177064 9794209 1436291..1436575 1 NC_014550.1 involved in the modulation of the specificity of the clpAP-mediated ATP-dependent protein degradation; ATP-dependent Clp protease adaptor protein ClpS 1436575 clpS 9794209 clpS Arthrobacter arilaitensis Re117 ATP-dependent Clp protease adaptor protein ClpS YP_003916470.1 1436291 D 861360 CDS YP_003916471.1 308177065 9793742 1436578..1437156 1 NC_014550.1 hypothetical protein 1437156 9793742 AARI_12920 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916471.1 1436578 D 861360 CDS YP_003916472.1 308177066 9795490 1437161..1438084 1 NC_014550.1 converts L-glutamate to D-glutamate, a component of peptidoglycan; glutamate racemase 1438084 murI 9795490 murI Arthrobacter arilaitensis Re117 glutamate racemase YP_003916472.1 1437161 D 861360 CDS YP_003916473.1 308177067 9794123 1438081..1439022 1 NC_014550.1 hypothetical protein 1439022 9794123 AARI_12940 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916473.1 1438081 D 861360 CDS YP_003916474.1 308177068 9795492 1439682..1440416 1 NC_014550.1 removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates; tRNA nucleotidyltransferase 1440416 rph 9795492 rph Arthrobacter arilaitensis Re117 tRNA nucleotidyltransferase YP_003916474.1 1439682 D 861360 CDS YP_003916475.1 308177069 9794308 1440413..1441045 1 NC_014550.1 hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions; nucleoside-triphosphatase 1441045 rdgB 9794308 rdgB Arthrobacter arilaitensis Re117 nucleoside-triphosphatase YP_003916475.1 1440413 D 861360 CDS YP_003916476.1 308177070 9794285 complement(1441126..1442031) 1 NC_014550.1 hypothetical protein 1442031 9794285 AARI_12980 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916476.1 1441126 R 861360 CDS YP_003916477.1 308177071 9795493 1442625..1442984 1 NC_014550.1 identified by match to protein family PF00392. This family of regulatory proteins consists of the N-terminal HTH region of GntR-like bacterial transcription factors. At the C-terminus there is usually an effector- binding/oligomerisation domain. The GntR-like proteins can be divided into six sub-families: MocR, YtrR, FadR, AraR, HutC and PlmA. Many of these proteins have been shown experimentally to be autoregulatory, enabling the prediction of operator sites and the discovery of cis/trans relationships; GntR family transcriptional regulator 1442984 9795493 AARI_12990 Arthrobacter arilaitensis Re117 GntR family transcriptional regulator YP_003916477.1 1442625 D 861360 CDS YP_003916478.1 308177072 9795494 1443014..1443931 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily (TC 3. A.1.y.z). ABCISSE: ABC transporter, ATP-binding protein (ABC), NO family (NO family systems represent few ABC proteins with unknown function and which are apparently unrelated to existent families); ABC transporter ATP-binding subunit 1443931 9795494 AARI_13000 Arthrobacter arilaitensis Re117 ABC transporter ATP-binding subunit YP_003916478.1 1443014 D 861360 CDS YP_003916479.1 308177073 9795495 1443928..1444623 1 NC_014550.1 TC 3.1.y.z. ABCISSE: ABC transporter, permease (IM); ABC transporter inner membrane subunit 1444623 9795495 AARI_13010 Arthrobacter arilaitensis Re117 ABC transporter inner membrane subunit YP_003916479.1 1443928 D 861360 CDS YP_003916480.1 308177074 9795496 1444814..1445311 1 NC_014550.1 hypothetical protein 1445311 9795496 AARI_13020 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916480.1 1444814 D 861360 CDS YP_003916481.1 308177075 9795497 1445525..1446526 1 NC_014550.1 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The beta chain is required for initiation of replication once it is clamped onto DNA. DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII complex. PolIII associates with the gamma complex (composed of gamma, delta, delta, psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex; DNA polymerase III subunit epsilon 1446526 9795497 AARI_13030 Arthrobacter arilaitensis Re117 DNA polymerase III subunit epsilon YP_003916481.1 1445525 D 861360 CDS YP_003916482.1 308177076 9795498 complement(1446607..1447542) 1 NC_014550.1 hypothetical protein 1447542 9795498 AARI_13040 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916482.1 1446607 R 861360 CDS YP_003916483.1 308177077 9795499 1447594..1448760 1 NC_014550.1 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3 ->5 double strand exonuclease that can open hairpins. It also has a 5 single-strand endonuclease activity; nuclease SbcCD subunit D 1448760 sbcD 9795499 sbcD Arthrobacter arilaitensis Re117 nuclease SbcCD subunit D YP_003916483.1 1447594 D 861360 CDS YP_003916484.1 308177078 9794375 1448757..1451828 1 NC_014550.1 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3 ->5 double strand exonuclease that can open hairpins. It also has a 5 single-strand endonuclease activity; nuclease SbcCD subunit C 1451828 sbcC 9794375 sbcC Arthrobacter arilaitensis Re117 nuclease SbcCD subunit C YP_003916484.1 1448757 D 861360 CDS YP_003916485.1 308177079 9794374 1451941..1453215 1 NC_014550.1 major facilitator superfamily (TC 2.A.1.y.z). Identified by match to protein family PF07690 (Major Facilitator Superfamily); MFS superfamily transporter 1453215 9794374 AARI_13070 Arthrobacter arilaitensis Re117 MFS superfamily transporter YP_003916485.1 1451941 D 861360 CDS YP_003916486.1 308177080 9795500 complement(1453321..1454016) 1 NC_014550.1 identified by match to PF09339: IclR helix-turn- helix domain. This family of bacterial transcriptional regulators groups several proteins, including gylR, a possible activator protein for the gylABX glycerol operon in Streptomyces, and iclR, the repressor of the acetate operon (also known as glyoxylate bypass operon) in Escherichia coli and Salmonella typhimurium; IclR family transcriptional regulator 1454016 9795500 AARI_13080 Arthrobacter arilaitensis Re117 IclR family transcriptional regulator YP_003916486.1 1453321 R 861360 CDS YP_003916487.1 308177081 9795501 1454280..1455620 1 NC_014550.1 major facilitator superfamily (MFS), metabolite:H+ symporter (MHS) family (TC 2.A.1.6.z); MFS superfamily transporter 1455620 9795501 AARI_13090 Arthrobacter arilaitensis Re117 MFS superfamily transporter YP_003916487.1 1454280 D 861360 CDS YP_003916488.1 308177082 9795502 1456546..1457043 1 NC_014550.1 hypothetical protein 1457043 9795502 AARI_13100 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916488.1 1456546 D 861360 CDS YP_003916489.1 308177083 9795503 1457063..1457314 1 NC_014550.1 hypothetical protein 1457314 9795503 AARI_13110 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916489.1 1457063 D 861360 CDS YP_003916490.1 308177084 9795504 complement(1457507..1458514) 1 NC_014550.1 match to protein domain PF00356. Numerous bacterial transcription regulatory proteins bind DNA via a helix- turn-helix (HTH) motif. These proteins are very diverse, but for convenience may be grouped into subfamilies on the basis of sequence similarity. One such family groups together a range of proteins, including ascG, ccpA, cytR, ebgR, fruR, galR, galS, lacI, malI, opnR, purF, rafR, rbtR and scrR. Within this family, the HTH motif is situated towards the N-terminus; LacI family transcriptional regulator 1458514 9795504 AARI_13120 Arthrobacter arilaitensis Re117 LacI family transcriptional regulator YP_003916490.1 1457507 R 861360 CDS YP_003916491.1 308177085 9795505 complement(1458628..1460283) 1 NC_014550.1 enzymes of this family comprise mostly alpha- amylases (EC 3.2.1.1); pullulanases (EC 3.2.1.41); cyclomaltodextrin glucanotransferase (EC 2.4.1.19); cyclomaltodextrinase (EC 3.2.1.54); trehalose-6-phosphate hydrolase (EC 3.2.1.93); malto-oligosyltrehalose trehalohydrolase (EC 3.2.1.141); glycosyl hydrolase family 13 1460283 9795505 AARI_13130 Arthrobacter arilaitensis Re117 glycosyl hydrolase family 13 YP_003916491.1 1458628 R 861360 CDS YP_003916492.1 308177086 9795506 1460583..1461851 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, carbohydrate uptake transporter-1 (CUT1) family (TC 3.A.1. 1.z). ABCISSE: ABC transporter, binding protein (BP), OSP-family (oligosaccharides or polyols), maltooligosaccharides import; maltooligosaccharides ABC transporter substrate-binding protein 1461851 9795506 AARI_13140 Arthrobacter arilaitensis Re117 maltooligosaccharides ABC transporter substrate-binding protein YP_003916492.1 1460583 D 861360 CDS YP_003916493.1 308177087 9795507 1461968..1463563 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, carbohydrate uptake transporter-1 (CUT1) family (TC 3.A.1. 1.z). ABCISSE: ABC transporter, permease (IM), OSP- family (oligosaccharides or polyols), maltooligosaccharides import; maltooligosaccharides ABC transporter inner membrane subunit 1463563 9795507 AARI_13150 Arthrobacter arilaitensis Re117 maltooligosaccharides ABC transporter inner membrane subunit YP_003916493.1 1461968 D 861360 CDS YP_003916494.1 308177088 9795508 1463563..1464477 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, carbohydrate uptake transporter-1 (CUT1) family (TC 3.A.1. 1.z). ABCISSE: ABC transporter, permease (IM), OSP- family (oligosaccharides or polyols), maltooligosaccharides import; maltooligosaccharides ABC transporter inner membrane subunit 1464477 9795508 AARI_13160 Arthrobacter arilaitensis Re117 maltooligosaccharides ABC transporter inner membrane subunit YP_003916494.1 1463563 D 861360 CDS YP_003916495.1 308177089 9795509 1464579..1465568 1 NC_014550.1 8 transmembrane helices predicted by TMHMM2.0; hypothetical protein 1465568 9795509 AARI_13170 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916495.1 1464579 D 861360 CDS YP_003916496.1 308177090 9795510 1465624..1466379 1 NC_014550.1 identified by match to protein domains PF02909 and PF00440; TetR family transcriptional regulator 1466379 9795510 AARI_13180 Arthrobacter arilaitensis Re117 TetR family transcriptional regulator YP_003916496.1 1465624 D 861360 CDS YP_003916497.1 308177091 9795511 1466480..1468036 1 NC_014550.1 major facilitator superfamily (TC 2.A.1.y.z). Identified by match to protein family PF07690 (Major Facilitator Superfamily); MFS superfamily transporter 1468036 9795511 AARI_13190 Arthrobacter arilaitensis Re117 MFS superfamily transporter YP_003916497.1 1466480 D 861360 CDS YP_003916498.1 308177092 9795512 1468080..1468496 1 NC_014550.1 hypothetical protein 1468496 9795512 AARI_13200 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916498.1 1468080 D 861360 CDS YP_003916499.1 308177093 9795513 complement(1468519..1469619) 1 NC_014550.1 identified by match to PF00487. Fatty acid desaturases catalyze the insertion of a double bond at the delta position of fatty acids; fatty acid desaturase 1469619 9795513 AARI_13210 Arthrobacter arilaitensis Re117 fatty acid desaturase YP_003916499.1 1468519 R 861360 CDS YP_003916500.1 308177094 9795514 complement(1469747..1471387) 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, () drug resistance ATPase-1 (Drug RA1) family (TC 3.A.1.120.z). ABCISSE: fused ATP-binding protein (ABC2), ART-family. Duplicated ATPase domains (PF00005); drug resistance ATP-binding protein 1471387 9795514 AARI_13220 Arthrobacter arilaitensis Re117 drug resistance ATP-binding protein YP_003916500.1 1469747 R 861360 CDS YP_003916501.1 308177095 9795515 1471471..1471836 1 NC_014550.1 identified by match to PF01022. ArsR-family transcriptional regulators include several proteins that appear to dissociate from DNA in the presence of metal ions; ArsR family transcriptional regulator 1471836 9795515 AARI_13230 Arthrobacter arilaitensis Re117 ArsR family transcriptional regulator YP_003916501.1 1471471 D 861360 CDS YP_003916502.1 308177096 9795516 complement(1472330..1473607) 1 NC_014550.1 transposase of ISAar13, ISL3 family 1473607 9795516 AARI_34840 Arthrobacter arilaitensis Re117 transposase of ISAar13, ISL3 family YP_003916502.1 1472330 R 861360 CDS YP_003916503.1 308177097 9795517 complement(1474555..1475217) 1 NC_014550.1 match to protein domain PF00156. This family includes a range of diverse phosphoribosyl transferase enzymes; phosphoribosyl transferase 1475217 9795517 AARI_13250 Arthrobacter arilaitensis Re117 phosphoribosyl transferase YP_003916503.1 1474555 R 861360 CDS YP_003916504.1 308177098 9795520 complement(1476668..1477777) 1 NC_014550.1 involved in the catabolism of tyrosine; 3,4-dihydroxyphenylacetate 2,3-dioxygenase 1477777 hpaD 9795520 hpaD Arthrobacter arilaitensis Re117 3,4-dihydroxyphenylacetate 2,3-dioxygenase YP_003916504.1 1476668 R 861360 CDS YP_003916505.1 308177099 9793971 complement(1477829..1479322) 1 NC_014550.1 5-carboxymethyl-2-hydroxymuconic-semialdehyde dehydrogenase catalyzes the formation of 5-carboxymethyl-2- hydroxymuconate from 5-carboxymethyl-2-hydroxymuconate semialdehyde; 5-carboxymethyl-2-hydroxymuconic-semialdehyde dehydrogenase 1479322 hpaE 9793971 hpaE Arthrobacter arilaitensis Re117 5-carboxymethyl-2-hydroxymuconic-semialdehyde dehydrogenase YP_003916505.1 1477829 R 861360 CDS YP_003916506.1 308177100 9793972 complement(1479397..1480056) 1 NC_014550.1 identified by match to protein family PF00392. This family of regulatory proteins consists of the N-terminal HTH region of GntR-like bacterial transcription factors. At the C-terminus there is usually an effector- binding/oligomerisation domain. The GntR-like proteins can be divided into six sub-families: MocR, YtrR, FadR, AraR, HutC and PlmA. Many of these proteins have been shown experimentally to be autoregulatory, enabling the prediction of operator sites and the discovery of cis/trans relationships; GntR family transcriptional regulator 1480056 9793972 AARI_13300 Arthrobacter arilaitensis Re117 GntR family transcriptional regulator YP_003916506.1 1479397 R 861360 CDS YP_003916507.1 308177101 9795521 complement(1480056..1481558) 1 NC_014550.1 involved in the homoprotocatechuic acid pathway. EC 5.3.3.10 (5-carboxymethyl-2-hydroxymuconate Delta- isomerase ) catalyses the conversion of 5-carboxymethyl- 2hydroxymuconate to 5-carboxy-2-oxohept-3-enedioate. The latter is converted to 2-hydroxyhepta-2,4-dienediotae by EC 4.1.1.68 (5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase); homoprotocatechuate catabolism bifunctional isomerase/decarboxylase 1481558 9795521 AARI_13310 Arthrobacter arilaitensis Re117 homoprotocatechuate catabolism bifunctional isomerase/decarboxylase YP_003916507.1 1480056 R 861360 CDS YP_003916508.1 308177102 9795522 complement(1481933..1483168) 1 NC_014550.1 TC 3.A.1.y.z. ABCISSE: ABC transporter, permease (IM); ABC transporter inner membrane subunit 1483168 9795522 AARI_13320 Arthrobacter arilaitensis Re117 ABC transporter inner membrane subunit YP_003916508.1 1481933 R 861360 CDS YP_003916509.1 308177103 9795523 complement(1483165..1483872) 1 NC_014550.1 TC 3.A.1.y.z. ABCISSE: ABC transporter, ATP-binding protein (ABC); ABC transporter ATP-binding subunit 1483872 9795523 AARI_13330 Arthrobacter arilaitensis Re117 ABC transporter ATP-binding subunit YP_003916509.1 1483165 R 861360 CDS YP_003916510.1 308177104 9795524 complement(1483862..1484872) 1 NC_014550.1 hypothetical protein 1484872 9795524 AARI_13340 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916510.1 1483862 R 861360 CDS YP_003916511.1 308177105 9795525 complement(1484869..1486176) 1 NC_014550.1 transposase of ISAar19, ISL3 family 1486176 9795525 AARI_34850 Arthrobacter arilaitensis Re117 transposase of ISAar19, ISL3 family YP_003916511.1 1484869 R 861360 CDS YP_003916512.1 308177106 9793427 1487062..1488360 1 NC_014550.1 transposase of ISAar10, IS1380 family 1488360 9793427 AARI_34860 Arthrobacter arilaitensis Re117 transposase of ISAar10, IS1380 family YP_003916512.1 1487062 D 861360 CDS YP_003916513.1 308177107 9795528 1494772..1496217 1 NC_014550.1 transposase of ISAar22, IS481 family 1496217 9795528 AARI_34870 Arthrobacter arilaitensis Re117 transposase of ISAar22, IS481 family YP_003916513.1 1494772 D 861360 CDS YP_003916514.1 308177108 9793429 1496480..1497772 1 NC_014550.1 match to protein family PF04464. Possibly involved in teichoic acid biosynthesis; transferase 1497772 9793429 AARI_13380 Arthrobacter arilaitensis Re117 transferase YP_003916514.1 1496480 D 861360 CDS YP_003916515.1 308177109 9795529 1498112..1499548 1 NC_014550.1 transposase of ISAar9, IS1380 family 1499548 9795529 AARI_34880 Arthrobacter arilaitensis Re117 transposase of ISAar9, IS1380 family YP_003916515.1 1498112 D 861360 CDS YP_003916516.1 308177110 9793430 complement(1499903..1501831) 1 NC_014550.1 involved in the biosynthesis of isoleucine, leucine and valine. Catalyses the dehydratation of 2, 3-dihydroxy-3- methylpentanoate and 2, 3-dihydroxy-3-methylbutanoate into 3-methyl-2-oxopentanoate and 2-oxoisovalerate, respectively; dihydroxy-acid dehydratase 1501831 ilvD 9793430 ilvD Arthrobacter arilaitensis Re117 dihydroxy-acid dehydratase YP_003916516.1 1499903 R 861360 CDS YP_003916517.1 308177111 9794005 1501917..1502696 1 NC_014550.1 identified by match to SM00530: Helix-turn-helix XRE-family like proteins. This is a large family of DNA binding helix-turn helix proteins that include a bacterial plasmid copy control protein, bacterial methylases, various bacteriophage transcription control proteins and a vegetative specific protein from Dictyostelium discoideum (Slime mould); DNA-binding protein 1502696 9794005 AARI_13400 Arthrobacter arilaitensis Re117 DNA-binding protein YP_003916517.1 1501917 D 861360 CDS YP_003916518.1 308177112 9795530 complement(1502860..1503552) 1 NC_014550.1 signal peptide predicted by SignalP 3.0 HMM (probability: 1.000) with cleavage site probability 0.646 between position 58 and 59; hypothetical protein 1503552 9795530 AARI_13410 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916518.1 1502860 R 861360 CDS YP_003916519.1 308177113 9795531 complement(1503817..1504566) 1 NC_014550.1 match to PS00120 pattern: lipases, serine active site; lipase/esterase 1504566 9795531 AARI_13420 Arthrobacter arilaitensis Re117 lipase/esterase YP_003916519.1 1503817 R 861360 CDS YP_003916520.1 308177114 9795532 complement(1504570..1505151) 1 NC_014550.1 hypothetical protein 1505151 9795532 AARI_13430 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916520.1 1504570 R 861360 CDS YP_003916521.1 308177115 9795533 1505358..1506086 1 NC_014550.1 identified by match to PF00293. Members of the Nudix hydrolase superfamily catalyze the hydrolysis of nucleoside diphosphates linked to other moieties. Substrates of nudix hydrolases include intact and oxidatively damaged nucleoside triphosphates, dinucleoside polyphosphates, nucleotide-sugars and dinucleotide enzymes. These substrates are metabolites or cell signaling molecules that require regulation during different stages of the cell cycle or during periods of stress. In general, the role of the nudix hydrolase is to sanitize the nucleotide pools and to maintain cell viability, thereby serving as surveillance and house- cleaning enzymes; NUDIX hydrolase 1506086 9795533 AARI_13440 Arthrobacter arilaitensis Re117 NUDIX hydrolase YP_003916521.1 1505358 D 861360 CDS YP_003916522.1 308177116 9795534 1506138..1507427 1 NC_014550.1 quinolinate synthetase A subunit. Quinolinate synthetase complex (A and B subunits) is involved in the de novo biosynthetic pathway of pyridine nucleotide formation. It catalyses the formation of quinolinic acid; quinolinate synthetase A subunit 1507427 nadA 9795534 nadA Arthrobacter arilaitensis Re117 quinolinate synthetase A subunit YP_003916522.1 1506138 D 861360 CDS YP_003916523.1 308177117 9794126 1507424..1509067 1 NC_014550.1 quinolinate synthetase B subunit. Quinolinate synthetase complex (A and B subunits) is involved in the de novo biosynthetic pathway of pyridine nucleotide formation. It catalyses the formation of quinolinic acid; L-aspartate oxidase 1509067 nadB 9794126 nadB Arthrobacter arilaitensis Re117 L-aspartate oxidase YP_003916523.1 1507424 D 861360 CDS YP_003916524.1 308177118 9794127 1509064..1509930 1 NC_014550.1 involved in the de novo synthesis of NAD in both prokaryotes and eukaryotes. It catalyses the reaction of quinolinic acid with 5-phosphoribosyl-1-pyrophosphate in the presence of Mg2+ to produce nicotinic acid mononucleotide, pyrophosphate and carbon dioxide; nicotinate-nucleotide diphosphorylase 1509930 nadC 9794127 nadC Arthrobacter arilaitensis Re117 nicotinate-nucleotide diphosphorylase YP_003916524.1 1509064 D 861360 CDS YP_003916525.1 308177119 9794128 1509927..1511069 1 NC_014550.1 identified by match to protein family PIRSF005572: cysteine desulfurase, NifS type. Cysteine desulfurase catalyses the following reaction: L-cysteine + [enzyme]- cysteine <=> L-alanine + [enzyme]-S-sulfanylcysteine. It is involved in the biosynthesis of iron-sulfur clusters, thio-nucleosides in tRNA, thiamine, biotin, lipoate and pyranopterin (molybdopterin) and functions by mobilizing sulfur; cysteine desulfurase 1511069 9794128 AARI_13480 Arthrobacter arilaitensis Re117 cysteine desulfurase YP_003916525.1 1509927 D 861360 CDS YP_003916526.1 308177120 9795535 1511315..1512127 1 NC_014550.1 match to PF08239: bacterial SH3 domain. A homologue of the SH3 domain has been found in a number of different bacterial proteins including glycyl-glycine endopeptidase, bacteriocin and some hypothetical proteins. Signal peptide predicted by SignalP 3.0 HMM (probability: 1.000) with cleavage site probability 0.938 between position 26 and 27; SH3 domain-containing protein 1512127 9795535 AARI_13490 Arthrobacter arilaitensis Re117 SH3 domain-containing protein YP_003916526.1 1511315 D 861360 CDS YP_003916527.1 308177121 9795536 1512205..1512789 1 NC_014550.1 match to PF08239: bacterial SH3 domain. A homologue of the SH3 domain has been found in a number of different bacterial proteins including glycyl-glycine endopeptidase, bacteriocin and some hypothetical proteins; SH3 domain-containing protein 1512789 9795536 AARI_13500 Arthrobacter arilaitensis Re117 SH3 domain-containing protein YP_003916527.1 1512205 D 861360 CDS YP_003916528.1 308177122 9795537 complement(1512873..1514300) 1 NC_014550.1 N-terminal section of the protein: match to protein family PF02557 (VanY, D-alanyl-D-alanine carboxypeptidase). C-terminal section of the protein: match to PF08239 (bacterial SH3 domain) protein family PF02557; D-alanyl-D-alanine carboxypeptidase 1514300 9795537 AARI_13510 Arthrobacter arilaitensis Re117 D-alanyl-D-alanine carboxypeptidase YP_003916528.1 1512873 R 861360 CDS YP_003916529.1 308177123 9795538 1514739..1515254 1 NC_014550.1 identified by match to PF00583: acetyltransferase (GNAT) family; GNAT family acetyltransferase 1515254 9795538 AARI_13520 Arthrobacter arilaitensis Re117 GNAT family acetyltransferase YP_003916529.1 1514739 D 861360 CDS YP_003916530.1 308177124 9795539 1515319..1515795 1 NC_014550.1 match to protein family PF08327; activator of Hsp90 ATPase 1-like protein 1515795 9795539 AARI_13530 Arthrobacter arilaitensis Re117 activator of Hsp90 ATPase 1-like protein YP_003916530.1 1515319 D 861360 CDS YP_003916531.1 308177125 9795540 complement(1515808..1516401) 1 NC_014550.1 match to protein domain PF01872. This domain is found in the C-terminus of the bifunctional deaminase- reductase in combination with PF00383 as well as in isolation in some archaebacterial proteins; RibD domain-containing protein 1516401 9795540 AARI_13540 Arthrobacter arilaitensis Re117 RibD domain-containing protein YP_003916531.1 1515808 R 861360 CDS YP_003916532.1 308177126 9795541 complement(1516513..1517202) 1 NC_014550.1 hypothetical protein 1517202 9795541 AARI_13550 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916532.1 1516513 R 861360 CDS YP_003916533.1 308177127 9795542 complement(1517327..1517785) 1 NC_014550.1 identified by match to protein family PF01047. Regulators with the marR-type HTH domain are present in bacteria and archaea and control a variety of biological functions, including resistance to multiple antibiotics, household disinfectants, organic solvents, oxidative stress agents and regulation of the virulence factor synthesis in pathogens of humans and plants. Many of the marR-like regulators respond to aromatic compounds; MarR family transcriptional regulator 1517785 9795542 AARI_13560 Arthrobacter arilaitensis Re117 MarR family transcriptional regulator YP_003916533.1 1517327 R 861360 CDS YP_003916534.1 308177128 9795543 complement(1517769..1518902) 1 NC_014550.1 identified by match to PF00296. Bacterial luciferase is a flavin monooxygenase that catalyses the oxidation of long-chain aldehydes and releases energy in the form of visible light, and which uses flavin as a substrate rather than a cofactor. There are structural similarities between bacterial luciferase and nonfluorescent flavoproteins (LuxF, FP390), alkanesulfonate monooxygenase (SsuD), and coenzyme F420- dependent terahydromethanopterin reductase, which make up clearly related families with somewhat different folds; luciferase-like monooxygenase 1518902 9795543 AARI_13570 Arthrobacter arilaitensis Re117 luciferase-like monooxygenase YP_003916534.1 1517769 R 861360 CDS YP_003916535.1 308177129 9795544 complement(1519019..1519687) 1 NC_014550.1 response regulators are key elements in two- component signal transduction systems, which enable bacteria to sense, respond, and adapt to a wide range of environments, stressors, and growth conditions; two-component system response regulator 1519687 9795544 AARI_13580 Arthrobacter arilaitensis Re117 two-component system response regulator YP_003916535.1 1519019 R 861360 CDS YP_003916536.1 308177130 9795545 1519834..1520568 1 NC_014550.1 5 transmembrane helices predicted by TMHMM2.0; hypothetical protein 1520568 9795545 AARI_13590 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916536.1 1519834 D 861360 CDS YP_003916537.1 308177131 9795546 complement(1520653..1524030) 1 NC_014550.1 Resistance-Nodulation-Cell Division (RND) superfamily (TC 2.A.6.y.z). Match to protein family PF00873 (AcrB/AcrD/AcrF family). Some Members of this family are involved in drug resistance; drug exporter of the RND superfamily 1524030 9795546 AARI_13600 Arthrobacter arilaitensis Re117 drug exporter of the RND superfamily YP_003916537.1 1520653 R 861360 CDS YP_003916538.1 308177132 9795547 1524302..1525747 1 NC_014550.1 transposase of ISAar22, IS481 family 1525747 9795547 AARI_34890 Arthrobacter arilaitensis Re117 transposase of ISAar22, IS481 family YP_003916538.1 1524302 D 861360 CDS YP_003916539.1 308177133 9795548 1526694..1526972 1 NC_014550.1 hypothetical protein 1526972 9795548 AARI_13620 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916539.1 1526694 D 861360 CDS YP_003916540.1 308177134 9795549 complement(1527042..1528529) 1 NC_014550.1 other name: malate:quinone oxidoreductase. Takes part in the citric acid cycle. It oxidises L-malate to oxaloacetate and donates electrons to ubiquinone-1 and other artificial acceptors or, via the electron transfer chain, to oxygen. NAD is not an acceptor and the natural direct acceptor for the enzyme is most likely a quinone; malate dehydrogenase (acceptor) 1528529 mqo 9795549 mqo Arthrobacter arilaitensis Re117 malate dehydrogenase (acceptor) YP_003916540.1 1527042 R 861360 CDS YP_003916541.1 308177135 9794104 complement(1528608..1530452) 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, peptide/opine/nickel uptake transporter (PepT) family (TC 3.A.1.5.z). ABCISSE: ABC transporter, binding protein (BP), OPN-family (oligopeptides and nickel), oligopeptides import; dipeptide/oligopeptide ABC transporter substrate-binding protein 1530452 9794104 AARI_13640 Arthrobacter arilaitensis Re117 dipeptide/oligopeptide ABC transporter substrate-binding protein YP_003916541.1 1528608 R 861360 CDS YP_003916542.1 308177136 9795550 complement(1530604..1531536) 1 NC_014550.1 match to PF02826 (D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain); D-isomer specific 2-hydroxyacid dehydrogenase family protein 1531536 9795550 AARI_13650 Arthrobacter arilaitensis Re117 D-isomer specific 2-hydroxyacid dehydrogenase family protein YP_003916542.1 1530604 R 861360 CDS YP_003916543.1 308177137 9793612 1532431..1532922 1 NC_014550.1 peroxiredoxin protects cells against toxicity from reactive oxygen species by reducing and detoxifying hydroperoxides. The Bcp protein shows substrate selectivity toward fatty acid hydroperoxides rather than hydrogen peroxide or alkyl hydroperoxides; peroxiredoxin 1532922 bcp 9793612 bcp Arthrobacter arilaitensis Re117 peroxiredoxin YP_003916543.1 1532431 D 861360 CDS YP_003916544.1 308177138 9793613 1533217..1533777 1 NC_014550.1 identified by match to protein family PF01047. Regulators with the marR-type HTH domain are present in bacteria and archaea and control a variety of biological functions, including resistance to multiple antibiotics, household disinfectants, organic solvents, oxidative stress agents and regulation of the virulence factor synthesis in pathogens of humans and plants. Many of the marR-like regulators respond to aromatic compounds; MarR family transcriptional regulator 1533777 9793613 AARI_13670 Arthrobacter arilaitensis Re117 MarR family transcriptional regulator YP_003916544.1 1533217 D 861360 CDS YP_003916545.1 308177139 9795552 complement(1533802..1535265) 1 NC_014550.1 identified by match to protein family PF01370: NAD dependent epimerase/dehydratase family. This family of proteins utilise NAD as a cofactor. The proteins in this family use nucleotide-sugar substrates for a variety of chemical reactions; NAD dependent epimerase/dehydratase family protein 1535265 9795552 AARI_13680 Arthrobacter arilaitensis Re117 NAD dependent epimerase/dehydratase family protein YP_003916545.1 1533802 R 861360 CDS YP_003916546.1 308177140 9795553 complement(1535262..1536092) 1 NC_014550.1 8 transmembrane helices predicted by TMHMM2.0; hypothetical protein 1536092 9795553 AARI_13690 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916546.1 1535262 R 861360 CDS YP_003916547.1 308177141 9795554 1536208..1536693 1 NC_014550.1 identified by match to protein family PF01047. Regulators with the marR-type HTH domain are present in bacteria and archaea and control a variety of biological functions, including resistance to multiple antibiotics, household disinfectants, organic solvents, oxidative stress agents and regulation of the virulence factor synthesis in pathogens of humans and plants. Many of the marR-like regulators respond to aromatic compounds; MarR family transcriptional regulator 1536693 9795554 AARI_13700 Arthrobacter arilaitensis Re117 MarR family transcriptional regulator YP_003916547.1 1536208 D 861360 CDS YP_003916548.1 308177142 9795555 1536700..1537809 1 NC_014550.1 identified by similarity to protein SP:Q9KK76 (Brevibacterium linens). A variety of isoprenoid compounds are synthesized by various organisms. In bacteria this pathway leads to the synthesis of isopentenyl tRNA, isoprenoid quinones, and sugar carrier lipids. Farnesyltranstransferase catalyzes the sequential addition of the three molecules of isopentenyl pyrophosphate onto dimethylallyl pyrophosphate to form geranylgeranyl pyrophosphate; farnesyltranstransferase 1537809 crtE 9795555 crtE Arthrobacter arilaitensis Re117 farnesyltranstransferase YP_003916548.1 1536700 D 861360 CDS YP_003916549.1 308177143 9793758 1537815..1538759 1 NC_014550.1 identified by similarity to protein SP:Q93QX6 (Corynebacterium glutamicum), match to protein family PF00494. Phytoene synthase catalyzes the conversion of two molecules of geranylgeranyl diphosphate (GGPP) into phytoene. It is the second step in the biosynthesis of carotenoids from isopentenyl diphosphate. It is found in all organisms that synthesize carotenoids: plants and photosynthetic bacteria as well as some non- photosynthetic bacteria and fungi; phytoene synthase 1538759 crtB 9793758 crtB Arthrobacter arilaitensis Re117 phytoene synthase YP_003916549.1 1537815 D 861360 CDS YP_003916550.1 308177144 9793757 1538756..1540348 1 NC_014550.1 identified by similarity to protein SP:Q93QX5 (Corynebacterium glutamicum), match to protein family TIGR02734. Involved in carotenoid biosynthesis. Phytoene is converted to lycopene by desaturation at four (two symmetrical pairs of) sites. This is achieved by two enzymes (CrtP and CrtQ) in cyanobacteria (Gloeobacter being an exception) and plants, but by a single enzyme in most other bacteria and in fungi. This single enzyme is called the bacterial-type phytoene desaturase, or CrtI; phytoene desaturase 1540348 crtI 9793757 crtI Arthrobacter arilaitensis Re117 phytoene desaturase YP_003916550.1 1538756 D 861360 CDS YP_003916551.1 308177145 9793761 1540345..1540707 1 NC_014550.1 identified by similarity to protein SP:Q93QX4 (Corynebacterium glutamicum). In Corynebacterium glutamicum MJ233C, CrtYe and CrtYf encode the proteins of a C50 carotenoid epsilon cyclase, which is involved in C50 carotenoid biosynthesis. It catalyzes the formation of flavuxanthin from lycopene; C50 carotenoid epsilon cyclase 1540707 crtYe 9793761 crtYe Arthrobacter arilaitensis Re117 C50 carotenoid epsilon cyclase YP_003916551.1 1540345 D 861360 CDS YP_003916552.1 308177146 9793762 1540697..1541053 1 NC_014550.1 identified by similarity to protein SP:Q93QX3 (Corynebacterium glutamicum). In Corynebacterium glutamicum MJ233C, CrtYe and CrtYf encode the proteins of a C50 carotenoid epsilon cyclase, which is involved in C50 carotenoid biosynthesis. It catalyzes the formation of flavuxanthin from lycopene; C50 carotenoid epsilon cyclase 1541053 crtYf 9793762 crtYf Arthrobacter arilaitensis Re117 C50 carotenoid epsilon cyclase YP_003916552.1 1540697 D 861360 CDS YP_003916553.1 308177147 9793763 1541050..1541913 1 NC_014550.1 identified by similarity to protein SP:Q93QX2 (Corynebacterium glutamicum). In Corynebacterium glutamicum MJ233C, CrtEb converts lycopene into the acyclic C50 carotenoid flaxuxanthin by the addition of two C5 isoprenoid groups; lycopene elongase 1541913 crtEb 9793763 crtEb Arthrobacter arilaitensis Re117 lycopene elongase YP_003916553.1 1541050 D 861360 CDS YP_003916554.1 308177148 9793760 1541940..1542455 1 NC_014550.1 catalyses the interconversion of isopentenyl diphosphate and dimethylallyl diphosphate. Dimethylallyl phosphate is the initial substrate for the biosynthesis of carotenoids and other long chain isoprenoids; isopentenyl-diphosphate delta-isomerase 1542455 idi 9793760 idi Arthrobacter arilaitensis Re117 isopentenyl-diphosphate delta-isomerase YP_003916554.1 1541940 D 861360 CDS YP_003916555.1 308177149 9793998 complement(1542616..1543077) 1 NC_014550.1 hypothetical protein 1543077 9793998 AARI_13780 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916555.1 1542616 R 861360 CDS YP_003916556.1 308177150 9795556 1543246..1544316 1 NC_014550.1 transposase of ISAar1, IS1595 family, ISSod11 group 1544316 9795556 AARI_34900 Arthrobacter arilaitensis Re117 transposase of ISAar1, IS1595 family, ISSod11 group YP_003916556.1 1543246 D 861360 CDS YP_003916557.1 308177151 9793432 1544871..1546769 1 NC_014550.1 acetolactate synthase catalyses the first common step in the biosynthesis of the 3 branched-chain amino acids. The first step involves the condensation of either pyruvate or 2-ketobutyrate with the two-carbon hydroxyethyl fragment derived from another pyruvate molecule, covalently bound to the coenzyme thiamine diphosphate. The resulting products are 2-acetolactate and 2-aceto2-hydroxybutanoate; acetolactate synthase large subunit 1546769 ilvB 9793432 ilvB Arthrobacter arilaitensis Re117 acetolactate synthase large subunit YP_003916557.1 1544871 D 861360 CDS YP_003916558.1 308177152 9794003 1546773..1547291 1 NC_014550.1 acetolactate synthase catalyses the first common step in the biosynthesis of the 3 branched-chain amino acids. The first step involves the condensation of either pyruvate or 2-ketobutyrate with the two-carbon hydroxyethyl fragment derived from another pyruvate molecule, covalently bound to the coenzyme thiamine diphosphate. The resulting products are 2-acetolactate and 2-aceto2-hydroxybutanoate; acetolactate synthase small subunit 1547291 ilvN 9794003 ilvN Arthrobacter arilaitensis Re117 acetolactate synthase small subunit YP_003916558.1 1546773 D 861360 CDS YP_003916559.1 308177153 9794007 1547416..1548447 1 NC_014550.1 catalyses the conversion of acetohydroxy acids into dihydroxy valerates. This reaction is the second in the synthetic pathway of the branched chain amino acids leucine, valine and isoleucine; ketol-acid reductoisomerase 1548447 ilvC 9794007 ilvC Arthrobacter arilaitensis Re117 ketol-acid reductoisomerase YP_003916559.1 1547416 D 861360 CDS YP_003916560.1 308177154 9794004 complement(1548637..1549293) 1 NC_014550.1 signal peptide predicted by SignalP 3.0 HMM (probability: 1.000) with cleavage site probability 0.464 between position 43 and 44; hypothetical protein 1549293 9794004 AARI_13820 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916560.1 1548637 R 861360 CDS YP_003916561.1 308177155 9795557 1549493..1550194 1 NC_014550.1 identified by match to protein domain PF08241; SAM-dependent methyltransferase 1550194 9795557 AARI_13830 Arthrobacter arilaitensis Re117 SAM-dependent methyltransferase YP_003916561.1 1549493 D 861360 CDS YP_003916562.1 308177156 9795558 1550673..1553306 1 NC_014550.1 match to PF00196: Bacterial regulatory proteins, luxR family; DNA binding domain-containing protein 1553306 9795558 AARI_13840 Arthrobacter arilaitensis Re117 DNA binding domain-containing protein YP_003916562.1 1550673 D 861360 CDS YP_003916563.1 308177157 9795559 1553303..1555969 1 NC_014550.1 match to PF00196: Bacterial regulatory proteins, luxR family; DNA binding domain-containing protein 1555969 9795559 AARI_13850 Arthrobacter arilaitensis Re117 DNA binding domain-containing protein YP_003916563.1 1553303 D 861360 CDS YP_003916564.1 308177158 9795560 complement(1556150..1556389) 1 NC_014550.1 hypothetical protein 1556389 9795560 AARI_13860 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916564.1 1556150 R 861360 CDS YP_003916565.1 308177159 9795561 1556576..1557883 1 NC_014550.1 transposase of ISAar20, ISL3 family 1557883 9795561 AARI_34910 Arthrobacter arilaitensis Re117 transposase of ISAar20, ISL3 family YP_003916565.1 1556576 D 861360 CDS YP_003916566.1 308177160 9793434 complement(1558628..1559935) 1 NC_014550.1 transposase of ISAar19, ISL3 family 1559935 9793434 AARI_34930 Arthrobacter arilaitensis Re117 transposase of ISAar19, ISL3 family YP_003916566.1 1558628 R 861360 CDS YP_003916567.1 308177161 9793436 1561047..1562405 1 NC_014550.1 sugar transferase 1562405 9793436 AARI_13870 Arthrobacter arilaitensis Re117 sugar transferase YP_003916567.1 1561047 D 861360 CDS YP_003916568.1 308177162 9795562 1562949..1564556 1 NC_014550.1 match to PF02018; carbohydrate binding domain-containing protein 1564556 9795562 AARI_13880 Arthrobacter arilaitensis Re117 carbohydrate binding domain-containing protein YP_003916568.1 1562949 D 861360 CDS YP_003916569.1 308177163 9795563 complement(1564632..1565600) 1 NC_014550.1 hypothetical protein 1565600 9795563 AARI_13890 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916569.1 1564632 R 861360 CDS YP_003916570.1 308177164 9795564 complement(1565593..1566123) 1 NC_014550.1 match to PF00132: Bacterial transferase hexapeptide repeat. A number of different transferase protein families contain this repeat, such as galactoside acetyltransferase- like proteins, the gamma-class of carbonic anhydrases, and tetrahydrodipicolinate-N-succinlytransferases; transferase 1566123 9795564 AARI_13900 Arthrobacter arilaitensis Re117 transferase YP_003916570.1 1565593 R 861360 CDS YP_003916571.1 308177165 9795565 complement(1566120..1567619) 1 NC_014550.1 match to protein family PF02706. This family includes proteins involved in lipopolysaccharide (lps) biosynthesis; lipopolysaccharide biosynthesis protein 1567619 9795565 AARI_13910 Arthrobacter arilaitensis Re117 lipopolysaccharide biosynthesis protein YP_003916571.1 1566120 R 861360 CDS YP_003916572.1 308177166 9795566 complement(1567733..1568680) 1 NC_014550.1 match to PF00535: glycosyl transferase family 2. This domain is found in a diverse family of glycosyl transferases that transfer the sugar from UDP-glucose, UDP- N-acetyl-galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids; glycosyl transferase family 2 1568680 9795566 AARI_13920 Arthrobacter arilaitensis Re117 glycosyl transferase family 2 YP_003916572.1 1567733 R 861360 CDS YP_003916573.1 308177167 9795567 1568822..1570147 1 NC_014550.1 10 transmembrane helices predicted by TMHMM2.0; hypothetical protein 1570147 9795567 AARI_13930 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916573.1 1568822 D 861360 CDS YP_003916574.1 308177168 9795568 complement(1570218..1570901) 1 NC_014550.1 hypothetical protein 1570901 9795568 AARI_13940 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916574.1 1570218 R 861360 CDS YP_003916575.1 308177169 9795569 1571099..1572655 1 NC_014550.1 14 transmembrane helices predicted by TMHMM2.0; hypothetical protein 1572655 9795569 AARI_13950 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916575.1 1571099 D 861360 CDS YP_003916576.1 308177170 9795570 1572683..1573582 1 NC_014550.1 identified by match to PF00686. This family includes a range of sulphotransferase proteins including flavonyl 3-sulphotransferase, aryl sulphotransferase, alcohol sulphotransferase, estrogen sulphotransferase and phenol-sulphating phenol sulphotransferase. These enzymes are responsible for the transfer of sulphate groups to specific compounds; sulfotransferase domain-containig protein 1573582 9795570 AARI_13960 Arthrobacter arilaitensis Re117 sulfotransferase domain-containig protein YP_003916576.1 1572683 D 861360 CDS YP_003916577.1 308177171 9795571 1573661..1574947 1 NC_014550.1 hypothetical protein 1574947 9795571 AARI_13970 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916577.1 1573661 D 861360 CDS YP_003916578.1 308177172 9795572 1575228..1579541 1 NC_014550.1 match to protein domain PF00801; PDK domain-containing protein 1579541 9795572 AARI_13980 Arthrobacter arilaitensis Re117 PDK domain-containing protein YP_003916578.1 1575228 D 861360 CDS YP_003916579.1 308177173 9795573 1579672..1581435 1 NC_014550.1 divalent anion:Na+ symporter (DASS) family (TC 2.A. 47.y.z). Functionally characterized proteins of the DASS family transport (1) organic di- and tricarboxylates of the Krebs Cycle as well as dicarboxylate amino acid, (2) inorganic sulfate and (3) phosphate; DASS family symporter 1581435 9795573 AARI_13990 Arthrobacter arilaitensis Re117 DASS family symporter YP_003916579.1 1579672 D 861360 CDS YP_003916580.1 308177174 9795574 1581812..1583089 1 NC_014550.1 transposase of ISAar15, ISL3 family 1583089 9795574 AARI_34950 Arthrobacter arilaitensis Re117 transposase of ISAar15, ISL3 family YP_003916580.1 1581812 D 861360 CDS YP_003916581.1 308177175 9793437 complement(1583191..1584342) 1 NC_014550.1 identified by match to PF01583. Ultimate step in biosynthesis of 3-phosphoadenosine 5-phosphosulfate (PAPS), the primary biological sulfuryl donor; adenylyl-sulfate kinase 1584342 cysC 9793437 cysC Arthrobacter arilaitensis Re117 adenylyl-sulfate kinase YP_003916581.1 1583191 R 861360 CDS YP_003916582.1 308177176 9793775 1584535..1585293 1 NC_014550.1 identified by similarity to protein SP:P65163 (Mycobacterium tuberculosis). This enzyme (PAPS 3- phosphatase) is considered as an important regulator of the sulfate assimilation pathway, by controlling the pools of PAP and PAPS; 3'-phosphoadenosine-5'-phosphosulfate 3'-phosphatase 1585293 cysQ 9793775 cysQ Arthrobacter arilaitensis Re117 3'-phosphoadenosine-5'-phosphosulfate 3'-phosphatase YP_003916582.1 1584535 D 861360 CDS YP_003916583.1 308177177 9793783 1585327..1586250 1 NC_014550.1 catalyses the formation of diphosphate and adenylyl sulphate from ATP and sulphate. This enzyme participates in 3 metabolic pathways: purine metabolism, selenoamino acid metabolism, and sulfur metabolism; sulfate adenylyltransferase small subunit 1586250 cysD 9793783 cysD Arthrobacter arilaitensis Re117 sulfate adenylyltransferase small subunit YP_003916583.1 1585327 D 861360 CDS YP_003916584.1 308177178 9793776 1586252..1587502 1 NC_014550.1 catalyses the formation of diphosphate and adenylyl sulphate from ATP and sulphate. This enzyme participates in 3 metabolic pathways: purine metabolism, selenoamino acid metabolism, and sulfur metabolism; sulfate adenylyltransferase large subunit 1587502 cysN 9793776 cysN Arthrobacter arilaitensis Re117 sulfate adenylyltransferase large subunit YP_003916584.1 1586252 D 861360 CDS YP_003916585.1 308177179 9793781 1587797..1588249 1 NC_014550.1 match to protein family PF08660. Possibly involved in the biosynthesis of an exopolysaccharide; oligosaccharide biosynthesis Alg14-like protein 1588249 9793781 AARI_14040 Arthrobacter arilaitensis Re117 oligosaccharide biosynthesis Alg14-like protein YP_003916585.1 1587797 D 861360 CDS YP_003916586.1 308177180 9795575 1588246..1588827 1 NC_014550.1 match to PF04101: Glycosyltransferase family 28 C- terminal domain. This family family comprises enzymes with a number of known activities; 1,2-diacylglycerol 3-beta- galactosyltransferase (EC 2.4.1.46); 1,2-diacylglycerol 3- beta-glucosyltransferase (EC 2.4.1.157); beta-N- acetylglucosamine transferase (EC 2.4.1); glycosyl transferase family 28 1588827 9795575 AARI_14050 Arthrobacter arilaitensis Re117 glycosyl transferase family 28 YP_003916586.1 1588246 D 861360 CDS YP_003916587.1 308177181 9795576 1589185..1590780 1 NC_014550.1 catalyzes the oxidation of D-3-phosphoglycerate to 3- phosphohydroxypyruvate, which is the first step in the biosynthesis of L-serine, using NAD+ as the oxidizing agent; phosphoglycerate dehydrogenase 1590780 serA 9795576 serA Arthrobacter arilaitensis Re117 phosphoglycerate dehydrogenase YP_003916587.1 1589185 D 861360 CDS YP_003916588.1 308177182 9794392 complement(1591216..1591329) 1 NC_014550.1 hypothetical protein 1591329 9794392 AARI_14070 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916588.1 1591216 R 861360 CDS YP_003916589.1 308177183 9795577 1591807..1593528 1 NC_014550.1 hypothetical protein 1593528 9795577 AARI_14080 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916589.1 1591807 D 861360 CDS YP_003916590.1 308177184 9795578 1593811..1594026 1 NC_014550.1 hypothetical protein 1594026 9795578 AARI_14090 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916590.1 1593811 D 861360 CDS YP_003916591.1 308177185 9795579 complement(1594299..1595744) 1 NC_014550.1 transposase of ISAar27, IS481 family 1595744 9795579 AARI_34960 Arthrobacter arilaitensis Re117 transposase of ISAar27, IS481 family YP_003916591.1 1594299 R 861360 CDS YP_003916592.1 308177186 9795580 1596324..1597601 1 NC_014550.1 transposase of ISAar13, ISL3 family 1597601 9795580 AARI_34970 Arthrobacter arilaitensis Re117 transposase of ISAar13, ISL3 family YP_003916592.1 1596324 D 861360 CDS YP_003916593.1 308177187 9793439 1597733..1598140 1 NC_014550.1 2 transmembrane helices predicted by TMHMM2.0; hypothetical protein 1598140 9793439 AARI_14110 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916593.1 1597733 D 861360 CDS YP_003916594.1 308177188 9795581 1598204..1600015 1 NC_014550.1 hypothetical protein 1600015 9795581 AARI_14120 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916594.1 1598204 D 861360 CDS YP_003916595.1 308177189 9795582 1600018..1600593 1 NC_014550.1 hypothetical protein 1600593 9795582 AARI_14130 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916595.1 1600018 D 861360 CDS YP_003916596.1 308177190 9795583 1600590..1605581 1 NC_014550.1 match to PF00535 and PF00534; hypothetical protein 1605581 9795583 AARI_14140 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916596.1 1600590 D 861360 CDS YP_003916597.1 308177191 9795584 1605868..1607610 1 NC_014550.1 match to PF00535: glycosyl transferase family 2. This domain is found in a diverse family of glycosyl transferases that transfer the sugar from UDP-glucose, UDP- N-acetyl-galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids; glycosyl transferase family 2 1607610 9795584 AARI_14150 Arthrobacter arilaitensis Re117 glycosyl transferase family 2 YP_003916597.1 1605868 D 861360 CDS YP_003916598.1 308177192 9795585 1607661..1608836 1 NC_014550.1 match to PF00534: Glycosyl transferases group 1. Proteins containing this domain transfer UDP, ADP, GDP or CMP linked sugars to a variety of substrates, including glycogen, fructose-6-phosphate and lipopolysaccharides. The bacterial enzymes are involved in various biosynthetic processes that include exopolysaccharide biosynthesis, lipopolysaccharide core biosynthesis and the biosynthesis of the slime polysaccaride colanic acid; glycosyl transferase family 1 1608836 9795585 AARI_14160 Arthrobacter arilaitensis Re117 glycosyl transferase family 1 YP_003916598.1 1607661 D 861360 CDS YP_003916599.1 308177193 9795586 1608847..1610592 1 NC_014550.1 match to PF00534: Glycosyl transferases group 1. Proteins containing this domain transfer UDP, ADP, GDP or CMP linked sugars to a variety of substrates, including glycogen, fructose-6-phosphate and lipopolysaccharides. The bacterial enzymes are involved in various biosynthetic processes that include exopolysaccharide biosynthesis, lipopolysaccharide core biosynthesis and the biosynthesis of the slime polysaccaride colanic acid; glycosyl transferase family 1 1610592 9795586 AARI_14170 Arthrobacter arilaitensis Re117 glycosyl transferase family 1 YP_003916599.1 1608847 D 861360 CDS YP_003916600.1 308177194 9795587 1610724..1611956 1 NC_014550.1 catalyzes the oxidation of UDP-N-acetyl-D- mannosamine to UDP-N-acetyl-D-mannosaminuronic acid. In Escherichia coli, UDP-N-acetyl-D-glucosamine 2-epimerase and UDP-N-acetyl-D-mannosamine dehydrogenase are responsible for the formation of UDP-N-acetyl-D- mannosaminuronic acid from UDP-N-acetyl-D-glucosamine; UDP-N-acetyl-D-mannosamine dehydrogenase 1611956 wecC 9795587 wecC Arthrobacter arilaitensis Re117 UDP-N-acetyl-D-mannosamine dehydrogenase YP_003916600.1 1610724 D 861360 CDS YP_003916601.1 308177195 9794503 1611983..1613167 1 NC_014550.1 catalyses the formation of UDP-N-acetyl-D- mannosamine from UDP-N-acetyl-D-glucosamine. The enzyme also hydrolyses the product to UDP and N-acetyl-D- mannosamine. In Escherichia coli, UDP-N-acetyl-D- glucosamine 2-epimerase and UDP-N-acetyl-D-mannosamine dehydrogenase are responsible for the formation of UDP-N- acetyl-D-mannosaminuronic acid from UDP-N-acetyl-D- glucosamine; UDP-N-acetylglucosamine 2-epimerase 1613167 wecB 9794503 wecB Arthrobacter arilaitensis Re117 UDP-N-acetylglucosamine 2-epimerase YP_003916601.1 1611983 D 861360 CDS YP_003916602.1 308177196 9794502 1613291..1614298 1 NC_014550.1 hypothetical protein 1614298 9794502 AARI_14200 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916602.1 1613291 D 861360 CDS YP_003916603.1 308177197 9795588 1614356..1615906 1 NC_014550.1 activates methionine and transfers it to tRNA(Met) as the first step in protein biosynthesis; methionine--tRNA ligase 1615906 metG 9795588 metG Arthrobacter arilaitensis Re117 methionine--tRNA ligase YP_003916603.1 1614356 D 861360 CDS YP_003916604.1 308177198 9794071 complement(1615976..1616668) 1 NC_014550.1 response regulators are key elements in two- component signal transduction systems, which enable bacteria to sense, respond, and adapt to a wide range of environments, stressors, and growth conditions; two-component system response regulator 1616668 9794071 AARI_14220 Arthrobacter arilaitensis Re117 two-component system response regulator YP_003916604.1 1615976 R 861360 CDS YP_003916605.1 308177199 9795589 complement(1616675..1617907) 1 NC_014550.1 protein-histidine kinases are key elements in two- component signal transduction systems, which enable bacteria to sense, respond, and adapt to a wide range of environments, stressors, and growth conditions; signal transduction histidine kinase 1617907 9795589 AARI_14230 Arthrobacter arilaitensis Re117 signal transduction histidine kinase YP_003916605.1 1616675 R 861360 CDS YP_003916606.1 308177200 9795590 1618090..1619148 1 NC_014550.1 involved in leucine biosynthesis. Catalyzes the oxidative decarboxylation of 3-isopropylmalate into 2-oxo- 4-methylvalerate; 3-isopropylmalate dehydrogenase 1619148 leuB 9795590 leuB Arthrobacter arilaitensis Re117 3-isopropylmalate dehydrogenase YP_003916606.1 1618090 D 861360 CDS YP_003916607.1 308177201 9794032 1619263..1620357 1 NC_014550.1 last step in the biosynthesis of the branched-chain amino acids L-isoleucine, L-valine and L-leucine; branched-chain-amino-acid transaminase 1620357 ilvE 9794032 ilvE Arthrobacter arilaitensis Re117 branched-chain-amino-acid transaminase YP_003916607.1 1619263 D 861360 CDS YP_003916608.1 308177202 9794006 1620432..1621463 1 NC_014550.1 catalyses the formation of UDP-glucose from UDP- galactose. Involved in the catabolism of galactose; UDP-glucose 4-epimerase 1621463 galE 9794006 galE Arthrobacter arilaitensis Re117 UDP-glucose 4-epimerase YP_003916608.1 1620432 D 861360 CDS YP_003916609.1 308177203 9793879 1621743..1623059 1 NC_014550.1 hypothetical protein 1623059 9793879 AARI_14270 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916609.1 1621743 D 861360 CDS YP_003916610.1 308177204 9795591 1623124..1624401 1 NC_014550.1 transposase of ISAar13, ISL3 family 1624401 9795591 AARI_34980 Arthrobacter arilaitensis Re117 transposase of ISAar13, ISL3 family YP_003916610.1 1623124 D 861360 CDS YP_003916611.1 308177205 9793440 1624604..1624744 1 NC_014550.1 hypothetical protein 1624744 9793440 AARI_14280 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916611.1 1624604 D 861360 CDS YP_003916612.1 308177206 9795592 1624848..1626155 1 NC_014550.1 transposase of ISAar19, ISL3 family 1626155 9795592 AARI_34990 Arthrobacter arilaitensis Re117 transposase of ISAar19, ISL3 family YP_003916612.1 1624848 D 861360 CDS YP_003916613.1 308177207 9793441 1626714..1627478 1 NC_014550.1 fumarylacetoacetate hydrolase family protein 1627478 9793441 AARI_14290 Arthrobacter arilaitensis Re117 fumarylacetoacetate hydrolase family protein YP_003916613.1 1626714 D 861360 CDS YP_003916614.1 308177208 9795593 1627581..1629086 1 NC_014550.1 glutamate--tRNA ligase 1629086 gltX 9795593 gltX Arthrobacter arilaitensis Re117 glutamate--tRNA ligase YP_003916614.1 1627581 D 861360 CDS YP_003916615.1 308177209 9793615 1630068..1631834 1 NC_014550.1 1 transmembrane helice predicted by TMHMM2.0; hypothetical protein 1631834 9793615 AARI_14310 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916615.1 1630068 D 861360 CDS YP_003916616.1 308177210 9795594 1631834..1633477 1 NC_014550.1 identified by match to protein family PF01926; GTPase 1633477 9795594 AARI_14320 Arthrobacter arilaitensis Re117 GTPase YP_003916616.1 1631834 D 861360 CDS YP_003916617.1 308177211 9795595 1633484..1634500 1 NC_014550.1 catalyses the following reaction: ATP + thiamine phosphate <=> ADP + thiamine diphosphate; thiamine-phosphate kinase 1634500 thiL 9795595 thiL Arthrobacter arilaitensis Re117 thiamine-phosphate kinase YP_003916617.1 1633484 D 861360 CDS YP_003916618.1 308177212 9794444 complement(1634528..1635253) 1 NC_014550.1 identified by match to PF09339: IclR helix-turn- helix domain. This family of bacterial transcriptional regulators groups several proteins, including gylR, a possible activator protein for the gylABX glycerol operon in Streptomyces, and iclR, the repressor of the acetate operon (also known as glyoxylate bypass operon) in Escherichia coli and Salmonella typhimurium; IclR family transcriptional regulator 1635253 9794444 AARI_14340 Arthrobacter arilaitensis Re117 IclR family transcriptional regulator YP_003916618.1 1634528 R 861360 CDS YP_003916619.1 308177213 9795596 1635367..1636815 1 NC_014550.1 catalyzes the isomerization between (2R,3S)-3- isopropylmalate and (2S)-2-isopropylmalate, via the formation of (2S)-2-isopropylmaleate. Involved in leucine biosynthesis; 3-isopropylmalate dehydratase large subunit 1636815 leuC 9795596 leuC Arthrobacter arilaitensis Re117 3-isopropylmalate dehydratase large subunit YP_003916619.1 1635367 D 861360 CDS YP_003916620.1 308177214 9794033 1636830..1637435 1 NC_014550.1 catalyzes the isomerization between (2R,3S)-3- isopropylmalate and (2S)-2-isopropylmalate, via the formation of (2S)-2-isopropylmaleate. Involved in leucine biosynthesis; 3-isopropylmalate dehydratase small subunit 1637435 leuD 9794033 leuD Arthrobacter arilaitensis Re117 3-isopropylmalate dehydratase small subunit YP_003916620.1 1636830 D 861360 CDS YP_003916621.1 308177215 9794034 1637693..1639012 1 NC_014550.1 catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine = phosphate + UDP-N-acetyl-3-(1-carboxyvinyl)-D-glucosamine; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1639012 murA 9794034 murA Arthrobacter arilaitensis Re117 UDP-N-acetylglucosamine 1-carboxyvinyltransferase YP_003916621.1 1637693 D 861360 CDS YP_003916622.1 308177216 9794116 1639030..1639794 1 NC_014550.1 1-acylglycerol-3-phosphate O-acyltransferase catalyzes the following reaction: Acyl-CoA + 1-acyl-sn- glycerol 3-phosphate <=> CoA + 1,2-diacyl-sn-glycerol 3- phosphate. It is involved in phospholipid biosynthesis; 1-acylglycerol-3-phosphate O-acyltransferase 1639794 9794116 AARI_14380 Arthrobacter arilaitensis Re117 1-acylglycerol-3-phosphate O-acyltransferase YP_003916622.1 1639030 D 861360 CDS YP_003916623.1 308177217 9795597 1639861..1640862 1 NC_014550.1 catalyzes the following reaction: sn-glycerol 3- phosphate + NAD(P)(+) <=> glycerone phosphate + NAD(P)H. Involved in glycerophospholipid metabolism; glycerol-3-phosphate dehydrogenase 1640862 gpsA 9795597 gpsA Arthrobacter arilaitensis Re117 glycerol-3-phosphate dehydrogenase YP_003916623.1 1639861 D 861360 CDS YP_003916624.1 308177218 9793934 1640862..1641974 1 NC_014550.1 participates in forming UDP-N-acetylmuramyl pentapeptide, the peptidoglycan precursor; D-alanine--D-alanine ligase 1641974 ddl 9793934 ddl Arthrobacter arilaitensis Re117 D-alanine--D-alanine ligase YP_003916624.1 1640862 D 861360 CDS YP_003916625.1 308177219 9793798 complement(1642049..1642498) 1 NC_014550.1 hypothetical protein 1642498 9793798 AARI_14410 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916625.1 1642049 R 861360 CDS YP_003916626.1 308177220 9795598 1642640..1643686 1 NC_014550.1 cell envelope-related transcriptional attenuator 1643686 9795598 AARI_14420 Arthrobacter arilaitensis Re117 cell envelope-related transcriptional attenuator YP_003916626.1 1642640 D 861360 CDS YP_003916627.1 308177221 9795599 1643710..1644678 1 NC_014550.1 match to PF2734 (DAK2; predicted phosphatase domain of the dihydroxyacetone kinase family) domain; DAK2 phosphatase domain-containing protein 1644678 9795599 AARI_14430 Arthrobacter arilaitensis Re117 DAK2 phosphatase domain-containing protein YP_003916627.1 1643710 D 861360 CDS YP_003916628.1 308177222 9795600 1644671..1646860 1 NC_014550.1 RecG protein is a junction-specific DNA helicase that drives branch migration of Holliday intermediates in genetic recombination and DNA repair; ATP-dependent DNA helicase RecG 1646860 recG 9795600 recG Arthrobacter arilaitensis Re117 ATP-dependent DNA helicase RecG YP_003916628.1 1644671 D 861360 CDS YP_003916629.1 308177223 9794288 1646880..1647464 1 NC_014550.1 match to PS00092 pattern: N-6 Adenine-specific DNA methylases signature. In prokaryotes, the major role of DNA methylation is to protect host DNA against degradation by restriction enzymes; adenine-specific DNA-methyltransferase 1647464 9794288 AARI_14450 Arthrobacter arilaitensis Re117 adenine-specific DNA-methyltransferase YP_003916629.1 1646880 D 861360 CDS YP_003916630.1 308177224 9795601 complement(1647441..1648223) 1 NC_014550.1 hypothetical protein 1648223 9795601 AARI_14460 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916630.1 1647441 R 861360 CDS YP_003916631.1 308177225 9795602 complement(1648220..1649431) 1 NC_014550.1 identified by match to PF00155: aminotransferase class I and II; aminotransferase 1649431 9795602 AARI_14470 Arthrobacter arilaitensis Re117 aminotransferase YP_003916631.1 1648220 R 861360 CDS YP_003916632.1 308177226 9795603 1649544..1650011 1 NC_014550.1 reversibly transfers an adenylyl group from ATP to 4-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate: ATP + pantetheine 4-phosphate = diphosphate + 3-dephospho-CoA; pantetheine-phosphate adenylyltransferase 1650011 coaD 9795603 coaD Arthrobacter arilaitensis Re117 pantetheine-phosphate adenylyltransferase YP_003916632.1 1649544 D 861360 CDS YP_003916633.1 308177227 9793749 1650104..1651003 1 NC_014550.1 catalyses the formation of UDP-glucose from glucose- 1-phosphate; UTP--glucose-1-phosphate uridylyltransferase 1651003 galU 9793749 galU Arthrobacter arilaitensis Re117 UTP--glucose-1-phosphate uridylyltransferase YP_003916633.1 1650104 D 861360 CDS YP_003916634.1 308177228 9793883 1651120..1652187 1 NC_014550.1 cell envelope-related transcriptional attenuator 1652187 9793883 AARI_14500 Arthrobacter arilaitensis Re117 cell envelope-related transcriptional attenuator YP_003916634.1 1651120 D 861360 CDS YP_003916635.1 308177229 9795604 1652324..1653172 1 NC_014550.1 TC 3.A.1.y.z. ABCISSE: ABC transporter, permease (IM), CLS-family (capsular polysaccharide, lipopolysaccharide and teichoic acids). A typical system is made of a conserved permease (IM) and an ATP-binding subunit (ABC). In addition to these proteins, capsular polysaccharide exporter systems require two accessory proteins to perform their function: a periplasmic or a lipid-anchored outer membrane protein called OMA and a cytoplasmic membrane protein MPA2; capsular polysaccharide/lipopolysaccharide/teichoic acids ABC transporter inner membrane subunit 1653172 9795604 AARI_14510 Arthrobacter arilaitensis Re117 capsular polysaccharide/lipopolysaccharide/teichoic acids ABC transporter inner membrane subunit YP_003916635.1 1652324 D 861360 CDS YP_003916636.1 308177230 9795605 1653183..1654049 1 NC_014550.1 TC 3.A.1.y.z. ABCISSE: ABC transporter, ATP-binding protein (ABC), CLS-family (capsular polysaccharide, lipopolysaccharide and teichoic acids). A typical system is made of a conserved permease (IM) and an ATP-binding subunit (ABC). In addition to these proteins, capsular polysaccharide exporter systems require two accessory proteins to perform their function: a periplasmic or a lipid-anchored outer membrane protein called OMA and a cytoplasmic membrane protein MPA2; capsular polysaccharide/lipopolysaccharide/teichoic acids ABC transporter ATP-binding subunit 1654049 9795605 AARI_14520 Arthrobacter arilaitensis Re117 capsular polysaccharide/lipopolysaccharide/teichoic acids ABC transporter ATP-binding subunit YP_003916636.1 1653183 D 861360 CDS YP_003916637.1 308177231 9795606 1654057..1655100 1 NC_014550.1 match to PF00535: glycosyl transferase family 2. This domain is found in a diverse family of glycosyl transferases that transfer the sugar from UDP-glucose, UDP- N-acetyl-galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids; glycosyl transferase family 2 1655100 9795606 AARI_14530 Arthrobacter arilaitensis Re117 glycosyl transferase family 2 YP_003916637.1 1654057 D 861360 CDS YP_003916638.1 308177232 9795607 1655097..1655915 1 NC_014550.1 match to protein family PF01066. Possibly involved in phospholipid biosynthesis; transferase 1655915 9795607 AARI_14540 Arthrobacter arilaitensis Re117 transferase YP_003916638.1 1655097 D 861360 CDS YP_003916639.1 308177233 9795608 1655955..1656845 1 NC_014550.1 match to PF00535: glycosyl transferase family 2. This domain is found in a diverse family of glycosyl transferases that transfer the sugar from UDP-glucose, UDP- N-acetyl-galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids; glycosyl transferase family 2 1656845 9795608 AARI_14550 Arthrobacter arilaitensis Re117 glycosyl transferase family 2 YP_003916639.1 1655955 D 861360 CDS YP_003916640.1 308177234 9795609 1656910..1657371 1 NC_014550.1 involved in teichoic acid biosynthesis; glycerol-3-phosphate cytidylyltransferase 1657371 tagD 9795609 tagD Arthrobacter arilaitensis Re117 glycerol-3-phosphate cytidylyltransferase YP_003916640.1 1656910 D 861360 CDS YP_003916641.1 308177235 9794422 1657421..1658794 1 NC_014550.1 hypothetical protein 1658794 9794422 AARI_14570 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916641.1 1657421 D 861360 CDS YP_003916642.1 308177236 9793442 complement(1661432..1662373) 1 NC_014550.1 transposase of ISAar44, IS3 family, IS3 group, orfB 1662373 9793442 AARI_35010 Arthrobacter arilaitensis Re117 transposase of ISAar44, IS3 family, IS3 group, orfB YP_003916642.1 1661432 R 861360 CDS YP_003916643.1 308177237 9793443 complement(1662472..1662909) 1 NC_014550.1 transposase of ISAar44, IS3 family, IS3 group, orfA 1662909 9793443 AARI_35020 Arthrobacter arilaitensis Re117 transposase of ISAar44, IS3 family, IS3 group, orfA YP_003916643.1 1662472 R 861360 CDS YP_003916644.1 308177238 9793444 complement(1663196..1664188) 1 NC_014550.1 transposase of ISAar46, IS3 family, IS3 group, orfB 1664188 9793444 AARI_35030 Arthrobacter arilaitensis Re117 transposase of ISAar46, IS3 family, IS3 group, orfB YP_003916644.1 1663196 R 861360 CDS YP_003916645.1 308177239 9793445 complement(1664185..1664577) 1 NC_014550.1 transposase of ISAar46, IS3 family, IS3 group, orfA 1664577 9793445 AARI_35040 Arthrobacter arilaitensis Re117 transposase of ISAar46, IS3 family, IS3 group, orfA YP_003916645.1 1664185 R 861360 CDS YP_003916646.1 308177240 9795612 1667982..1668260 1 NC_014550.1 transposase of ISAar3, IS3 family, IS407 group, orfA 1668260 9795612 AARI_35050 Arthrobacter arilaitensis Re117 transposase of ISAar3, IS3 family, IS407 group, orfA YP_003916646.1 1667982 D 861360 CDS YP_003916647.1 308177241 9793449 complement(1669332..1670273) 1 NC_014550.1 transposase of ISAar44, IS3 family, IS3 group, orfB 1670273 9793449 AARI_35080 Arthrobacter arilaitensis Re117 transposase of ISAar44, IS3 family, IS3 group, orfB YP_003916647.1 1669332 R 861360 CDS YP_003916648.1 308177242 9793450 complement(1670372..1670809) 1 NC_014550.1 transposase of ISAar44, IS3 family, IS3 group, orfA 1670809 9793450 AARI_35090 Arthrobacter arilaitensis Re117 transposase of ISAar44, IS3 family, IS3 group, orfA YP_003916648.1 1670372 R 861360 CDS YP_003916649.1 308177243 9793452 complement(1670954..1671244) 1 NC_014550.1 transposase of ISAar46, IS3 family, IS3 group, orfA 1671244 9793452 AARI_35110 Arthrobacter arilaitensis Re117 transposase of ISAar46, IS3 family, IS3 group, orfA YP_003916649.1 1670954 R 861360 CDS YP_003916650.1 308177244 9793454 1672311..1673984 1 NC_014550.1 hypothetical protein 1673984 9793454 AARI_14600 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916650.1 1672311 D 861360 CDS YP_003916651.1 308177245 9795613 1674378..1674899 1 NC_014550.1 hypothetical protein 1674899 9795613 AARI_14610 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916651.1 1674378 D 861360 CDS YP_003916652.1 308177246 9795614 1674902..1675105 1 NC_014550.1 ribosomal protein L32 is part of the 50S ribosomal subunit; 50S ribosomal protein L32 1675105 rpmF 9795614 rpmF Arthrobacter arilaitensis Re117 50S ribosomal protein L32 YP_003916652.1 1674902 D 861360 CDS YP_003916653.1 308177247 9794338 1675130..1675807 1 NC_014550.1 digests double-stranded RNA. Involved in the processing of ribosomal RNA precursors and of some mRNAs; ribonuclease III 1675807 rnc 9794338 rnc Arthrobacter arilaitensis Re117 ribonuclease III YP_003916653.1 1675130 D 861360 CDS YP_003916654.1 308177248 9794304 1675819..1676742 1 NC_014550.1 formamidopyrimidine-DNA glycosylases is a trifunctional DNA base excision repair enzyme that removes a wide range of oxidation-damaged bases (N-glycosylase activity; EC:3.2.2.23) and cleaves both the 3- and 5- phosphodiester bonds of the resulting apurinic/apyrimidinic site (AP lyase activity; EC:4.2.99. 18). It has a preference for oxidised purines, excising oxidized purine bases such as 7,8-dihydro-8- oxoguanine (8-oxoG). Its AP (apurinic/apyrimidinic) lyase activity introduces nicks in the DNA strand, cleaving the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3- and 5-phosphates; formamidopyrimidine-DNA glycosylase 1676742 mutM 9794304 mutM Arthrobacter arilaitensis Re117 formamidopyrimidine-DNA glycosylase YP_003916654.1 1675819 D 861360 CDS YP_003916655.1 308177249 9794124 complement(1676944..1677756) 1 NC_014550.1 match to protein family PF00144: beta-lactamase; hypothetical protein 1677756 9794124 AARI_14650 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916655.1 1676944 R 861360 CDS YP_003916656.1 308177250 9795615 1677906..1681478 1 NC_014550.1 identified by match to protein family TIGR02168. Smc participates in chromosomal partition during cell division. Component of a cohesin-like complex composed of scpA, scpB and smc; chromosome segregation protein Smc 1681478 smc 9795615 smc Arthrobacter arilaitensis Re117 chromosome segregation protein Smc YP_003916656.1 1677906 D 861360 CDS YP_003916657.1 308177251 9794397 complement(1681553..1682734) 1 NC_014550.1 drug:H+ antiporter-1 (12 Spanner) (DHA1) family transporter (TC 2.A.1.2.z). Match to PR01035 (Tetracycline resistance protein signature); multidrug efflux permease 1682734 9794397 AARI_14670 Arthrobacter arilaitensis Re117 multidrug efflux permease YP_003916657.1 1681553 R 861360 CDS YP_003916658.1 308177252 9795616 1682962..1684143 1 NC_014550.1 identified by match to protein family TIGR00064. FtsY is a functional homolog of SRP receptor. Integral membrane proteins, are specifically recognized by a direct interaction between their noncleaved signal anchor sequences and the bacterial signal recognition particle (SRP) consisting of Ffh and 4.5S RNA. Recognition occurs during synthesis at the ribosome and leads to a cotranslational targeting to SecYE that is mediated by FtsY and the hydrolysis of GTP; signal recognition particle-docking protein FtsY 1684143 ftsY 9795616 ftsY Arthrobacter arilaitensis Re117 signal recognition particle-docking protein FtsY YP_003916658.1 1682962 D 861360 CDS YP_003916659.1 308177253 9793870 complement(1684605..1685252) 1 NC_014550.1 3-methyladenine DNA glycosylase is a base excision- repair protein. It is responsible for the hydrolysis of the deoxyribose N-glycosidic bond, excising 3- methyladenine from damaged DNA; 3-methyladenine DNA glycosylase 1685252 9793870 AARI_14690 Arthrobacter arilaitensis Re117 3-methyladenine DNA glycosylase YP_003916659.1 1684605 R 861360 CDS YP_003916660.1 308177254 9795617 1685591..1686811 1 NC_014550.1 involved in the uptake of ammonia. Ammonia channel transporter (Amt) family (TC 1.A.11.y.z). The generalized transport reactions catalyzed by members of the Amt family are suggested to be: NH4+ (out) <--> NH4+ (in); ammonia transporter 1686811 amt 9795617 amt Arthrobacter arilaitensis Re117 ammonia transporter YP_003916660.1 1685591 D 861360 CDS YP_003916661.1 308177255 9793665 1687046..1689148 1 NC_014550.1 decomposes hydrogen peroxide to molecular oxygen and water. Its main function is to protect cells from the toxic effects of hydrogen peroxide; catalase 1689148 9793665 AARI_14710 Arthrobacter arilaitensis Re117 catalase YP_003916661.1 1687046 D 861360 CDS YP_003916662.1 308177256 9795618 1689246..1690376 1 NC_014550.1 identified by match to PF03631 (ribonuclease_BN, ribonuclease BN-like family): this family contains integral membrane proteins with 5 to 6 predicted transmembrane spans. The family includes ribonuclease BN, which is involved in tRNA maturation; ribonuclease BN-like protein 1690376 9795618 AARI_14720 Arthrobacter arilaitensis Re117 ribonuclease BN-like protein YP_003916662.1 1689246 D 861360 CDS YP_003916663.1 308177257 9795619 1690479..1690955 1 NC_014550.1 identified by match to PF01243: pyridoxamine 5- phosphate oxidase. This entry represents the FMN-binding domain present in pyridoxamine 5-phosphate oxidases, as well as in a number of proteins that have not been demonstrated to have enzymatic activity; FMN binding domain-containing protein 1690955 9795619 AARI_14730 Arthrobacter arilaitensis Re117 FMN binding domain-containing protein YP_003916663.1 1690479 D 861360 CDS YP_003916664.1 308177258 9795620 complement(1691084..1691275) 1 NC_014550.1 identified by match to protein family PF05532. CsbD is a bacterial general stress response protein. Its expression is mediated by sigma-B, an alternative sigma factor. The role of CsbD in stress response is unclear; CsbD family protein 1691275 9795620 AARI_14740 Arthrobacter arilaitensis Re117 CsbD family protein YP_003916664.1 1691084 R 861360 CDS YP_003916665.1 308177259 9795621 complement(1691507..1693216) 1 NC_014550.1 major facilitator superfamily, drug:H+ antiporter-2 (14 spanner) (DHA2) family (TC 2.A.1.3.z). Identified by match to protein family TIGR00711; EmrB/QacA subfamily drug resistance transporter 1693216 9795621 AARI_14750 Arthrobacter arilaitensis Re117 EmrB/QacA subfamily drug resistance transporter YP_003916665.1 1691507 R 861360 CDS YP_003916666.1 308177260 9795622 complement(1693254..1693919) 1 NC_014550.1 transcriptional regulator 1693919 9795622 AARI_14760 Arthrobacter arilaitensis Re117 transcriptional regulator YP_003916666.1 1693254 R 861360 CDS YP_003916667.1 308177261 9795623 1694274..1695335 1 NC_014550.1 hypothetical protein 1695335 9795623 AARI_14770 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916667.1 1694274 D 861360 CDS YP_003916668.1 308177262 9795624 1695332..1696699 1 NC_014550.1 match to protein family PF02585 and PF05401. Possibly involved in polysaccharide synthesis; hypothetical protein 1696699 9795624 AARI_14780 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916668.1 1695332 D 861360 CDS YP_003916669.1 308177263 9795625 1696692..1697426 1 NC_014550.1 match to PF00535: glycosyl transferase family 2. This domain is found in a diverse family of glycosyl transferases that transfer the sugar from UDP-glucose, UDP- N-acetyl-galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids; glycosyl transferase family 2 1697426 9795625 AARI_14790 Arthrobacter arilaitensis Re117 glycosyl transferase family 2 YP_003916669.1 1696692 D 861360 CDS YP_003916670.1 308177264 9795626 complement(1697535..1697978) 1 NC_014550.1 hypothetical protein 1697978 9795626 AARI_14800 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916670.1 1697535 R 861360 CDS YP_003916671.1 308177265 9795627 complement(1698304..1699731) 1 NC_014550.1 hypothetical protein 1699731 9795627 AARI_14810 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916671.1 1698304 R 861360 CDS YP_003916672.1 308177266 9795628 complement(1699728..1700258) 1 NC_014550.1 hypothetical protein 1700258 9795628 AARI_14820 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916672.1 1699728 R 861360 CDS YP_003916673.1 308177267 9795629 complement(1700454..1701179) 1 NC_014550.1 hypothetical protein 1701179 9795629 AARI_14830 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916673.1 1700454 R 861360 CDS YP_003916674.1 308177268 9795630 1701450..1703015 1 NC_014550.1 identified by match to protein family TIGR00959. Integral membrane proteins, are specifically recognized by a direct interaction between their noncleaved signal anchor sequences and the bacterial signal recognition particle (SRP) consisting of Ffh and 4.5S RNA. Recognition occurs during synthesis at the ribosome and leads to a cotranslational targeting to SecYE that is mediated by FtsY and the hydrolysis of GTP; signal recognition particle protein Ffh 1703015 ffh 9795630 ffh Arthrobacter arilaitensis Re117 signal recognition particle protein Ffh YP_003916674.1 1701450 D 861360 CDS YP_003916675.1 308177269 9793848 complement(1703369..1703851) 1 NC_014550.1 hypothetical protein 1703851 9793848 AARI_14850 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916675.1 1703369 R 861360 CDS YP_003916676.1 308177270 9795631 complement(1703983..1704432) 1 NC_014550.1 hypothetical protein 1704432 9795631 AARI_14860 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916676.1 1703983 R 861360 CDS YP_003916677.1 308177271 9795632 1704604..1705167 1 NC_014550.1 identified by match to protein family PF01047. Regulators with the marR-type HTH domain are present in bacteria and archaea and control a variety of biological functions, including resistance to multiple antibiotics, household disinfectants, organic solvents, oxidative stress agents and regulation of the virulence factor synthesis in pathogens of humans and plants. Many of the marR-like regulators respond to aromatic compounds; MarR family transcriptional regulator 1705167 9795632 AARI_14870 Arthrobacter arilaitensis Re117 MarR family transcriptional regulator YP_003916677.1 1704604 D 861360 CDS YP_003916678.1 308177272 9795633 1705394..1705669 1 NC_014550.1 hypothetical protein 1705669 9795633 AARI_14880 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916678.1 1705394 D 861360 CDS YP_003916679.1 308177273 9795634 1706002..1707195 1 NC_014550.1 match to the inorganic pyrophosphatase (PS00387) and Trp-Asp (WD) repeats (PS00678) signatures; hypothetical protein 1707195 9795634 AARI_14890 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916679.1 1706002 D 861360 CDS YP_003916680.1 308177274 9795635 1707340..1708539 1 NC_014550.1 transposase of ISAar21, IS4 family, IS4 group 1708539 9795635 AARI_35130 Arthrobacter arilaitensis Re117 transposase of ISAar21, IS4 family, IS4 group YP_003916680.1 1707340 D 861360 CDS YP_003916681.1 308177275 9793455 complement(1709202..1710509) 1 NC_014550.1 transposase of ISAar19, ISL3 family 1710509 9793455 AARI_35140 Arthrobacter arilaitensis Re117 transposase of ISAar19, ISL3 family YP_003916681.1 1709202 R 861360 CDS YP_003916682.1 308177276 9793456 1710732..1712102 1 NC_014550.1 match to PF00534: Glycosyl transferases group 1. Proteins containing this domain transfer UDP, ADP, GDP or CMP linked sugars to a variety of substrates, including glycogen, fructose-6-phosphate and lipopolysaccharides. The bacterial enzymes are involved in various biosynthetic processes that include exopolysaccharide biosynthesis, lipopolysaccharide core biosynthesis and the biosynthesis of the slime polysaccaride colanic acid; glycosyl transferase family 1 1712102 9793456 AARI_14900 Arthrobacter arilaitensis Re117 glycosyl transferase family 1 YP_003916682.1 1710732 D 861360 CDS YP_003916683.1 308177277 9795636 1712722..1714029 1 NC_014550.1 transposase of ISAar23, ISL3 family 1714029 9795636 AARI_35150 Arthrobacter arilaitensis Re117 transposase of ISAar23, ISL3 family YP_003916683.1 1712722 D 861360 CDS YP_003916684.1 308177278 9793459 1715295..1715405 1 NC_014550.1 hypothetical protein 1715405 9793459 AARI_14910 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916684.1 1715295 D 861360 CDS YP_003916685.1 308177279 9795637 1715572..1716849 1 NC_014550.1 transposase of ISAar14, ISL3 family 1716849 9795637 AARI_35180 Arthrobacter arilaitensis Re117 transposase of ISAar14, ISL3 family YP_003916685.1 1715572 D 861360 CDS YP_003916686.1 308177280 9793462 1718677..1719876 1 NC_014550.1 transposase of ISAar21, IS4 family, IS4 group 1719876 9793462 AARI_35210 Arthrobacter arilaitensis Re117 transposase of ISAar21, IS4 family, IS4 group YP_003916686.1 1718677 D 861360 CDS YP_003916687.1 308177281 9793463 complement(1720034..1721746) 1 NC_014550.1 match to protein family PF00501. This family of enzymes includes luciferase, long chain fatty acid Co-A ligase, acetyl-CoA synthetase and various other closely- related synthetases; fatty-acid--Co-A ligase 1721746 9793463 AARI_14920 Arthrobacter arilaitensis Re117 fatty-acid--Co-A ligase YP_003916687.1 1720034 R 861360 CDS YP_003916688.1 308177282 9795638 complement(1721984..1723690) 1 NC_014550.1 match to protein family PF00501. This family of enzymes includes luciferase, long chain fatty acid Co-A ligase, acetyl-CoA synthetase and various other closely- related synthetases; fatty-acid--Co-A ligase 1723690 9795638 AARI_14930 Arthrobacter arilaitensis Re117 fatty-acid--Co-A ligase YP_003916688.1 1721984 R 861360 CDS YP_003916689.1 308177283 9795639 complement(1723893..1724960) 1 NC_014550.1 thermonuclease catalyzes the hydrolysis of both DNA and RNA at the 5-position of the phosphodiester; thermonuclease 1724960 9795639 AARI_14940 Arthrobacter arilaitensis Re117 thermonuclease YP_003916689.1 1723893 R 861360 CDS YP_003916690.1 308177284 9795640 complement(1725216..1726274) 1 NC_014550.1 thermonuclease catalyzes the hydrolysis of both DNA and RNA at the 5-position of the phosphodiester; thermonuclease 1726274 9795640 AARI_14950 Arthrobacter arilaitensis Re117 thermonuclease YP_003916690.1 1725216 R 861360 CDS YP_003916691.1 308177285 9795641 1726482..1727351 1 NC_014550.1 ring-cleavage extradiol dioxygenase 1727351 9795641 AARI_14960 Arthrobacter arilaitensis Re117 ring-cleavage extradiol dioxygenase YP_003916691.1 1726482 D 861360 CDS YP_003916692.1 308177286 9795642 complement(1727459..1728232) 1 NC_014550.1 match to PF00132: Bacterial transferase hexapeptide repeat. A number of different transferase protein families contain this repeat, such as galactoside acetyltransferase- like proteins, the gamma-class of carbonic anhydrases, and tetrahydrodipicolinate-N-succinlytransferases; transferase 1728232 9795642 AARI_14970 Arthrobacter arilaitensis Re117 transferase YP_003916692.1 1727459 R 861360 CDS YP_003916693.1 308177287 9795643 complement(1728312..1730120) 1 NC_014550.1 match to PF00534: Glycosyl transferases group 1. Proteins containing this domain transfer UDP, ADP, GDP or CMP linked sugars to a variety of substrates, including glycogen, fructose-6-phosphate and lipopolysaccharides. The bacterial enzymes are involved in various biosynthetic processes that include exopolysaccharide biosynthesis, lipopolysaccharide core biosynthesis and the biosynthesis of the slime polysaccaride colanic acid; glycosyl transferase family 1 1730120 9795643 AARI_14980 Arthrobacter arilaitensis Re117 glycosyl transferase family 1 YP_003916693.1 1728312 R 861360 CDS YP_003916694.1 308177288 9795646 1730973..1731101 1 NC_014550.1 hypothetical protein 1731101 9795646 AARI_15010 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916694.1 1730973 D 861360 CDS YP_003916695.1 308177289 9795647 complement(1731224..1732234) 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, iron chelate uptake transporter (FeCT) family (TC 3.A.1.14.z). ABCISSE: ABC transporter, binding protein (BP), ISVH- family (iron siderophores, vitamin B12 and hemin); iron-siderophore ABC transporter substrate-binding protein 1732234 9795647 AARI_15020 Arthrobacter arilaitensis Re117 iron-siderophore ABC transporter substrate-binding protein YP_003916695.1 1731224 R 861360 CDS YP_003916696.1 308177290 9795648 1732446..1733435 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, iron chelate uptake transporter (FeCT) family (TC 3.A.1.14.z). ABCISSE: ABC transporter, permease (IM), ISVH-family (iron siderophores, vitamin B12 and hemin); iron-siderophore ABC transporter inner membrane subunit 1733435 9795648 AARI_15030 Arthrobacter arilaitensis Re117 iron-siderophore ABC transporter inner membrane subunit YP_003916696.1 1732446 D 861360 CDS YP_003916697.1 308177291 9795649 1733432..1734487 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, iron chelate uptake transporter (FeCT) family (TC 3.A.1.14.z). ABCISSE: ABC transporter, permease (IM), ISVH-family (iron siderophores, vitamin B12 and hemin); iron-siderophore ABC transporter inner membrane subunit 1734487 9795649 AARI_15040 Arthrobacter arilaitensis Re117 iron-siderophore ABC transporter inner membrane subunit YP_003916697.1 1733432 D 861360 CDS YP_003916698.1 308177292 9795650 1734552..1736279 1 NC_014550.1 identified by match to PF01844; HNH endonuclease domain-containing protein 1736279 9795650 AARI_15050 Arthrobacter arilaitensis Re117 HNH endonuclease domain-containing protein YP_003916698.1 1734552 D 861360 CDS YP_003916699.1 308177293 9795651 complement(1736325..1736954) 1 NC_014550.1 resistance to homoSer/Thr (RhtB) family protein (TC 2.A.76.y.z). The family includes homoserine, threonine and leucine efflux proteins. The transport reaction presumably catalyzed by members of the RhtB family is: amino acid (in) + nH+ (out) <--> amino acid (out) + nH+ (in); RHBT family amino acid transporter 1736954 9795651 AARI_15060 Arthrobacter arilaitensis Re117 RHBT family amino acid transporter YP_003916699.1 1736325 R 861360 CDS YP_003916700.1 308177294 9795652 1737205..1737615 1 NC_014550.1 30S ribosomal protein S16 1737615 rpsP 9795652 rpsP Arthrobacter arilaitensis Re117 30S ribosomal protein S16 YP_003916700.1 1737205 D 861360 CDS YP_003916701.1 308177295 9794363 1737618..1737860 1 NC_014550.1 hypothetical protein 1737860 9794363 AARI_15080 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916701.1 1737618 D 861360 CDS YP_003916702.1 308177296 9795653 1738015..1738557 1 NC_014550.1 essential for efficient processing of 16S rRNA. It is needed in a step prior to rbfA during the maturation of 16S rRNA; 16S rRNA-processing protein RimM 1738557 rimM 9795653 rimM Arthrobacter arilaitensis Re117 16S rRNA-processing protein RimM YP_003916702.1 1738015 D 861360 CDS YP_003916703.1 308177297 9794301 1738561..1739385 1 NC_014550.1 specifically methylates guanosine-37 in various tRNAs; tRNA (guanine-N(1)-)-methyltransferase 1739385 trmD 9794301 trmD Arthrobacter arilaitensis Re117 tRNA (guanine-N(1)-)-methyltransferase YP_003916703.1 1738561 D 861360 CDS YP_003916704.1 308177298 9794465 1739636..1739995 1 NC_014550.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 1739995 rplS 9794465 rplS Arthrobacter arilaitensis Re117 50S ribosomal protein L19 YP_003916704.1 1739636 D 861360 CDS YP_003916705.1 308177299 9794326 1740009..1740656 1 NC_014550.1 signal peptidases remove the signal peptides from secretory proteins. In prokaryotes three types of signal peptidases are known: type I (gene lepB) which is responsible for the processing of the majority of exported pre-proteins; type II (gene lsp) which only process lipoproteins, and a third type involved in the processing of pili subunits; signal peptidase I 1740656 lepB 9794326 lepB Arthrobacter arilaitensis Re117 signal peptidase I YP_003916705.1 1740009 D 861360 CDS YP_003916706.1 308177300 9794030 1741080..1743521 1 NC_014550.1 hypothetical protein 1743521 9794030 AARI_15130 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916706.1 1741080 D 861360 CDS YP_003916707.1 308177301 9795654 1743695..1744282 1 NC_014550.1 signal peptide predicted by SignalP 3.0 HMM (probability: 1.000) with cleavage site probability 0.703 between position 44 and 45; hypothetical protein 1744282 9795654 AARI_15140 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916707.1 1743695 D 861360 CDS YP_003916708.1 308177302 9795655 1744429..1745154 1 NC_014550.1 non-secretory protein prediction by SignalP 3.0 HMM; signal peptidase I-like protein 1745154 9795655 AARI_15150 Arthrobacter arilaitensis Re117 signal peptidase I-like protein YP_003916708.1 1744429 D 861360 CDS YP_003916709.1 308177303 9795656 1745166..1745891 1 NC_014550.1 recognizes and cleaves the RNA strand of RNA-DNA heteroduplexes; ribonuclease HII 1745891 rnhB 9795656 rnhB Arthrobacter arilaitensis Re117 ribonuclease HII YP_003916709.1 1745166 D 861360 CDS YP_003916710.1 308177304 9794305 1745891..1746211 1 NC_014550.1 hypothetical protein 1746211 9794305 AARI_15170 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916710.1 1745891 D 861360 CDS YP_003916711.1 308177305 9795657 complement(1746307..1747200) 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, quaternary amine uptake transporter (QAT) family (TC 3.A.1. 12.z). ABCISSE: ABC transporter, binding protein (BP), OTCN-family (osmoprotectants, taurine, cyanate and nitrate). Part of an uptake system of osmoprotrectants such as glycine betaine, carnitine, choline, proline betaine and L-proline; osmoprotectant (glycine betaine/carnitine/choline/L-proline) ABC transporter substrate-binding protein 1747200 9795657 AARI_15180 Arthrobacter arilaitensis Re117 osmoprotectant (glycine betaine/carnitine/choline/L-proline) ABC transporter substrate-binding protein YP_003916711.1 1746307 R 861360 CDS YP_003916712.1 308177306 9795658 complement(1747309..1748205) 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, quaternary amine uptake transporter (QAT) family (TC 3.A.1. 12.z). ABCISSE: ABC transporter, permease (IM), OTCN- family (osmoprotectants, taurine, cyanate and nitrate). Part of an uptake system of osmoprotrectants such as glycine betaine, carnitine, choline, proline betaine and L- proline; osmoprotectant (glycine betaine/carnitine/choline/L-proline) ABC transporter inner membrane subunit 1748205 9795658 AARI_15190 Arthrobacter arilaitensis Re117 osmoprotectant (glycine betaine/carnitine/choline/L-proline) ABC transporter inner membrane subunit YP_003916712.1 1747309 R 861360 CDS YP_003916713.1 308177307 9795659 complement(1748205..1749473) 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, quaternary amine uptake transporter (QAT) family (TC 3.A.1. 12.z). ABCISSE: ABC transporter, ATP-binding protein (ABC), OTCN-family (osmoprotectants, taurine, cyanate and nitrate). Part of an uptake system of osmoprotrectants such as glycine betaine, carnitine, choline, proline betaine and L-proline; osmoprotectant (glycine betaine/carnitine/choline/L-proline) ABC transporter ATP-binding subunit 1749473 9795659 AARI_15200 Arthrobacter arilaitensis Re117 osmoprotectant (glycine betaine/carnitine/choline/L-proline) ABC transporter ATP-binding subunit YP_003916713.1 1748205 R 861360 CDS YP_003916714.1 308177308 9795660 complement(1749948..1751225) 1 NC_014550.1 transposase of ISAar13, ISL3 family 1751225 9795660 AARI_35220 Arthrobacter arilaitensis Re117 transposase of ISAar13, ISL3 family YP_003916714.1 1749948 R 861360 CDS YP_003916715.1 308177309 9793464 1751494..1751856 1 NC_014550.1 hypothetical protein 1751856 9793464 AARI_15210 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916715.1 1751494 D 861360 CDS YP_003916716.1 308177310 9795661 1751853..1753406 1 NC_014550.1 match to protein family TIGR00368; Mg chelatase-like protein 1753406 9795661 AARI_15220 Arthrobacter arilaitensis Re117 Mg chelatase-like protein YP_003916716.1 1751853 D 861360 CDS YP_003916717.1 308177311 9795662 1753415..1754659 1 NC_014550.1 the SMF family (DNA processing chain A, dprA) are a group of bacterial proteins. In Helicobacter pylori, dprA is required for natural chromosomal and plasmid transformation; smf family protein 1754659 9795662 AARI_15230 Arthrobacter arilaitensis Re117 smf family protein YP_003916717.1 1753415 D 861360 CDS YP_003916718.1 308177312 9795663 1754679..1755683 1 NC_014550.1 site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids; tyrosine recombinase subunit XerC 1755683 xerC 9795663 xerC Arthrobacter arilaitensis Re117 tyrosine recombinase subunit XerC YP_003916718.1 1754679 D 861360 CDS YP_003916719.1 308177313 9794507 1755826..1756329 1 NC_014550.1 hypothetical protein 1756329 9794507 AARI_15250 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916719.1 1755826 D 861360 CDS YP_003916720.1 308177314 9795664 1756624..1757004 1 NC_014550.1 match to PS00082 extradiol ring-cleavage dioxygenases signature; ring-cleavage extradiol dioxygenase 1757004 9795664 AARI_15260 Arthrobacter arilaitensis Re117 ring-cleavage extradiol dioxygenase YP_003916720.1 1756624 D 861360 CDS YP_003916721.1 308177315 9795665 complement(1757007..1757582) 1 NC_014550.1 match to protein domain PF01872. This domain is found in the C-terminus of the bifunctional deaminase- reductase in combination with PF00383 as well as in isolation in some archaebacterial proteins; RibD domain-containing protein 1757582 9795665 AARI_15270 Arthrobacter arilaitensis Re117 RibD domain-containing protein YP_003916721.1 1757007 R 861360 CDS YP_003916722.1 308177316 9795666 complement(1757774..1759021) 1 NC_014550.1 catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP; 3-oxoacyl-ACP synthase 2 1759021 9795666 AARI_15280 Arthrobacter arilaitensis Re117 3-oxoacyl-ACP synthase 2 YP_003916722.1 1757774 R 861360 CDS YP_003916723.1 308177317 9795667 complement(1759142..1759387) 1 NC_014550.1 also named fatty acid synthase ACP. Carrier of the growing fatty acid chain in fatty acid biosynthesis; ACP 1759387 acpP 9795667 acpP Arthrobacter arilaitensis Re117 ACP YP_003916723.1 1759142 R 861360 CDS YP_003916724.1 308177318 9793652 complement(1759610..1760533) 1 NC_014550.1 involved in the initiation of fatty-acid biosynthesis in bacteria; malonyl CoA-ACP transacylase 1760533 fabD 9793652 fabD Arthrobacter arilaitensis Re117 malonyl CoA-ACP transacylase YP_003916724.1 1759610 R 861360 CDS YP_003916725.1 308177319 9793837 complement(1760710..1761921) 1 NC_014550.1 hypothetical protein 1761921 9793837 AARI_15310 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916725.1 1760710 R 861360 CDS YP_003916726.1 308177320 9795668 complement(1762055..1764829) 1 NC_014550.1 the pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3); pyruvate dehydrogenase E1 component subunit alpha 1764829 aceE 9795668 aceE Arthrobacter arilaitensis Re117 pyruvate dehydrogenase E1 component subunit alpha YP_003916726.1 1762055 R 861360 CDS YP_003916727.1 308177321 9793649 1765162..1765578 1 NC_014550.1 hypothetical protein 1765578 9793649 AARI_15330 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916727.1 1765162 D 861360 CDS YP_003916728.1 308177322 9795669 1765578..1766030 1 NC_014550.1 thiol-specific antioxidant proteins confer a protective role in cells through their peroxidase activity in which hydrogen peroxide, peroxynitrate, and organic hydroperoxides are reduced and detoxified using reducing equivalents derived from either thioredoxin, glutathione, trypanothione and AhpF; thiol-specific antioxidant protein 1766030 9795669 AARI_15340 Arthrobacter arilaitensis Re117 thiol-specific antioxidant protein YP_003916728.1 1765578 D 861360 CDS YP_003916729.1 308177323 9793616 complement(1766464..1766721) 1 NC_014550.1 hypothetical protein 1766721 9793616 AARI_15350 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916729.1 1766464 R 861360 CDS YP_003916730.1 308177324 9793617 1767101..1767709 1 NC_014550.1 identified by match to protein domain PF08241; SAM-dependent methyltransferase 1767709 9793617 AARI_15360 Arthrobacter arilaitensis Re117 SAM-dependent methyltransferase YP_003916730.1 1767101 D 861360 CDS YP_003916731.1 308177325 9795672 1767969..1768631 1 NC_014550.1 5 transmembrane helices predicted by TMHMM2.0; hypothetical protein 1768631 9795672 AARI_15370 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916731.1 1767969 D 861360 CDS YP_003916732.1 308177326 9795673 1768618..1768911 1 NC_014550.1 transcriptional regulator 1768911 9795673 AARI_15380 Arthrobacter arilaitensis Re117 transcriptional regulator YP_003916732.1 1768618 D 861360 CDS YP_003916733.1 308177327 9795674 1769073..1769267 1 NC_014550.1 identified by match to protein family PF05532. CsbD is a bacterial general stress response protein. Its expression is mediated by sigma-B, an alternative sigma factor. The role of CsbD in stress response is unclear; CsbD family protein 1769267 9795674 AARI_15390 Arthrobacter arilaitensis Re117 CsbD family protein YP_003916733.1 1769073 D 861360 CDS YP_003916734.1 308177328 9795675 complement(1769354..1770580) 1 NC_014550.1 match to protein domain PF05175. This domain is found in ribosomal RNA small subunit methyltransferase C as well as other methyltransferases; methyltransferase 1770580 9795675 AARI_15400 Arthrobacter arilaitensis Re117 methyltransferase YP_003916734.1 1769354 R 861360 CDS YP_003916735.1 308177329 9795676 complement(1770656..1771879) 1 NC_014550.1 match to PF04101: Glycosyltransferase family 28 N- terminal domain. This family family comprises enzymes with a number of known activities; 1,2-diacylglycerol 3-beta- galactosyltransferase (EC 2.4.1.46); 1,2-diacylglycerol 3- beta-glucosyltransferase (EC 2.4.1.157); beta-N- acetylglucosamine transferase (EC 2.4.1); glycosyl transferase family 28 1771879 9795676 AARI_15410 Arthrobacter arilaitensis Re117 glycosyl transferase family 28 YP_003916735.1 1770656 R 861360 CDS YP_003916736.1 308177330 9795677 1771974..1772615 1 NC_014550.1 match to PF00440: bacterial regulatory proteins, tetR family; transcriptional regulator 1772615 9795677 AARI_15420 Arthrobacter arilaitensis Re117 transcriptional regulator YP_003916736.1 1771974 D 861360 CDS YP_003916737.1 308177331 9795678 1772732..1773877 1 NC_014550.1 removes the acetyl group from N-acetyl-ornithine. Involved in arginine biosynthesis; acetylornithine deacetylase 1773877 argE 9795678 argE Arthrobacter arilaitensis Re117 acetylornithine deacetylase YP_003916737.1 1772732 D 861360 CDS YP_003916738.1 308177332 9793675 1773928..1775148 1 NC_014550.1 major facilitator superfamily (MFS), metabolite:H+ symporter (MHS) family (TC 2.A.1.6.z); MFS superfamily transporter 1775148 9793675 AARI_15440 Arthrobacter arilaitensis Re117 MFS superfamily transporter YP_003916738.1 1773928 D 861360 CDS YP_003916739.1 308177333 9795679 complement(1775229..1775918) 1 NC_014550.1 identified by match to protein family PF03006: HlyIII, Haemolysin-III related; hemolysin III-like protein 1775918 9795679 AARI_15450 Arthrobacter arilaitensis Re117 hemolysin III-like protein YP_003916739.1 1775229 R 861360 CDS YP_003916740.1 308177334 9795680 1776032..1776964 1 NC_014550.1 match to protein family PF06414. This family consists of several bacterial zeta toxin proteins. Zeta toxin is thought to be part of a postregulational killing system in bacteria. It relies on antitoxin/toxin systems that secure stable inheritance of low and medium copy number plasmids during cell division and kill cells that have lost the plasmid; zeta toxin-like protein 1776964 9795680 AARI_15460 Arthrobacter arilaitensis Re117 zeta toxin-like protein YP_003916740.1 1776032 D 861360 CDS YP_003916741.1 308177335 9795681 complement(1777047..1777307) 1 NC_014550.1 3 transmembrane helices predicted by TMHMM2.0; hypothetical protein 1777307 9795681 AARI_15470 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916741.1 1777047 R 861360 CDS YP_003916742.1 308177336 9795682 1777627..1778133 1 NC_014550.1 catalyzes the phosphoryl transfer from ATP to gluconate. The resulting product, gluconate-6-phoshate, is an important precursor of gluconate metabolism; gluconokinase 1778133 9795682 AARI_15480 Arthrobacter arilaitensis Re117 gluconokinase YP_003916742.1 1777627 D 861360 CDS YP_003916743.1 308177337 9795683 1778201..1779616 1 NC_014550.1 Gluconate:H+ Symporter (GntP) Family (TC 2.A.8.y.z). Match to protein family PF02447; gluconate permease 1779616 gntP 9795683 gntP Arthrobacter arilaitensis Re117 gluconate permease YP_003916743.1 1778201 D 861360 CDS YP_003916744.1 308177338 9793932 1779898..1780500 1 NC_014550.1 hypothetical protein 1780500 9793932 AARI_15500 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916744.1 1779898 D 861360 CDS YP_003916745.1 308177339 9795684 complement(1780601..1781335) 1 NC_014550.1 match to PF00392: bacterial regulatory proteins, gntR family, and to PF07729: FCD domain; GntR family transcriptional regulator 1781335 9795684 AARI_15510 Arthrobacter arilaitensis Re117 GntR family transcriptional regulator YP_003916745.1 1780601 R 861360 CDS YP_003916746.1 308177340 9795685 1781545..1782984 1 NC_014550.1 involved in the pentose phosphate pathway. Catalyzes the oxidative decarboxylation of 6- phosphogluconate into ribulose 5-phosphate; phosphogluconate dehydrogenase 1782984 gnd 9795685 gnd Arthrobacter arilaitensis Re117 phosphogluconate dehydrogenase YP_003916746.1 1781545 D 861360 CDS YP_003916747.1 308177341 9793930 complement(1783087..1783611) 1 NC_014550.1 hypothetical protein 1783611 9793930 AARI_15530 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916747.1 1783087 R 861360 CDS YP_003916748.1 308177342 9795686 complement(1783691..1784281) 1 NC_014550.1 transcriptional regulator 1784281 9795686 AARI_15540 Arthrobacter arilaitensis Re117 transcriptional regulator YP_003916748.1 1783691 R 861360 CDS YP_003916749.1 308177343 9795687 1784374..1784766 1 NC_014550.1 4 transmembrane helices predicted by TMHMM2.0; hypothetical protein 1784766 9795687 AARI_15550 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916749.1 1784374 D 861360 CDS YP_003916750.1 308177344 9795688 1784819..1785829 1 NC_014550.1 NADP-dependent oxidoreductase 1785829 9795688 AARI_15560 Arthrobacter arilaitensis Re117 NADP-dependent oxidoreductase YP_003916750.1 1784819 D 861360 CDS YP_003916751.1 308177345 9795689 1785886..1786419 1 NC_014550.1 1 transmembrane helice predicted by TMHMM2.0; hypothetical protein 1786419 9795689 AARI_15570 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916751.1 1785886 D 861360 CDS YP_003916752.1 308177346 9795690 complement(1786420..1786920) 1 NC_014550.1 identified by match to PF00583: acetyltransferase (GNAT) family; GNAT family acetyltransferase 1786920 9795690 AARI_15580 Arthrobacter arilaitensis Re117 GNAT family acetyltransferase YP_003916752.1 1786420 R 861360 CDS YP_003916753.1 308177347 9795691 complement(1786923..1789184) 1 NC_014550.1 excinuclease ABC catalyses nucleotide excision repair in a multi-step process; excinuclease ABC subunit A 1789184 uvrA 9795691 uvrA Arthrobacter arilaitensis Re117 excinuclease ABC subunit A YP_003916753.1 1786923 R 861360 CDS YP_003916754.1 308177348 9794495 1789315..1789866 1 NC_014550.1 match to PS51257: prokaryotic membrane lipoprotein lipid attachment site profile; hypothetical protein 1789866 9794495 AARI_15600 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916754.1 1789315 D 861360 CDS YP_003916755.1 308177349 9795692 1790164..1791444 1 NC_014550.1 Dicarboxylate/Amino Acid:Cation (Na+ or H+) symporter (DAACS) family (TC 2.A.23.y.z). The members of the DAACS family catalyze Na+ and/or H+ symport together with (a) a Krebs cycle dicarboxylate (malate, succinate, or fumarate), (b) a dicarboxylic amino acid (glutamate or aspartate), (c) a small, semipolar, neutral amino acid (Ala, Ser, Cys, Thr), (d) both neutral and acidic amino acids or (e) most zwitterionic and dibasic amino acids; dicarboxylate/amino acid transporter 1791444 9795692 AARI_15610 Arthrobacter arilaitensis Re117 dicarboxylate/amino acid transporter YP_003916755.1 1790164 D 861360 CDS YP_003916756.1 308177350 9795693 complement(1791629..1792213) 1 NC_014550.1 catalyses the first step of the synthesis of L- cysteine from L-serine; serine O-acetyltransferase 1792213 cysE 9795693 cysE Arthrobacter arilaitensis Re117 serine O-acetyltransferase YP_003916756.1 1791629 R 861360 CDS YP_003916757.1 308177351 9793778 complement(1792357..1793292) 1 NC_014550.1 responsible for the formation of cysteine from O- acetyl-serine and hydrogen sulfide with the concomitant release of acetic acid; cysteine synthase 1793292 cysK 9793778 cysK Arthrobacter arilaitensis Re117 cysteine synthase YP_003916757.1 1792357 R 861360 CDS YP_003916758.1 308177352 9793780 complement(1793419..1794039) 1 NC_014550.1 plays a role in preventing oxidative-stress damage caused by reactive oxygen species by reducing the oxidized form of methionine back to methionine and thereby reactivating peptides that had been damaged; peptide-methionine (S)-S-oxide reductase 1794039 msrA 9793780 msrA Arthrobacter arilaitensis Re117 peptide-methionine (S)-S-oxide reductase YP_003916758.1 1793419 R 861360 CDS YP_003916759.1 308177353 9794111 1794078..1795031 1 NC_014550.1 hypothetical protein 1795031 9794111 AARI_15650 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916759.1 1794078 D 861360 CDS YP_003916760.1 308177354 9795694 1795044..1795427 1 NC_014550.1 hypothetical protein 1795427 9795694 AARI_15660 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916760.1 1795044 D 861360 CDS YP_003916761.1 308177355 9795695 complement(1795481..1795699) 1 NC_014550.1 hypothetical protein 1795699 9795695 AARI_15670 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916761.1 1795481 R 861360 CDS YP_003916762.1 308177356 9795696 complement(1795696..1796736) 1 NC_014550.1 signal peptide predicted by SignalP 3.0 HMM (probability: 1.000) with cleavage site probability 0.987 between position 31 and 32; hypothetical protein 1796736 9795696 AARI_15680 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916762.1 1795696 R 861360 CDS YP_003916763.1 308177357 9795697 complement(1796805..1797431) 1 NC_014550.1 signal peptide predicted by SignalP 3.0 HMM (probability: 1.000) with cleavage site probability 0.697 between position 29 and 30; hypothetical protein 1797431 9795697 AARI_15690 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916763.1 1796805 R 861360 CDS YP_003916764.1 308177358 9795698 complement(1797472..1799778) 1 NC_014550.1 match to PF00149. The metallophosphoesterase motif is found in a large number of proteins invoved in phosphoryation. These include Ser/Thr phosphatases, DNA polymerase, exonucleases, and other phosphatases; metallophosphoesterase domain-containing protein 1799778 9795698 AARI_15700 Arthrobacter arilaitensis Re117 metallophosphoesterase domain-containing protein YP_003916764.1 1797472 R 861360 CDS YP_003916765.1 308177359 9795699 complement(1800122..1800901) 1 NC_014550.1 hypothetical protein 1800901 9795699 AARI_15710 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916765.1 1800122 R 861360 CDS YP_003916766.1 308177360 9795700 1801611..1803068 1 NC_014550.1 catalyses the reversible oxidation and phosphorylation of D-glyceraldehyde-3-phosphate to 1,3- diphospho-glycerate; glyceraldehyde-3-phosphate dehydrogenase 1803068 gap 9795700 gap Arthrobacter arilaitensis Re117 glyceraldehyde-3-phosphate dehydrogenase YP_003916766.1 1801611 D 861360 CDS YP_003916767.1 308177361 9795704 complement(1803888..1804460) 1 NC_014550.1 involved in polypeptide synthesis by removal of the formyl-group from methionine in growing polypeptides; peptide deformylase 1804460 def 9795704 def Arthrobacter arilaitensis Re117 peptide deformylase YP_003916767.1 1803888 R 861360 CDS YP_003916768.1 308177362 9793799 complement(1804485..1805633) 1 NC_014550.1 possibly involved in the metabolism of lipids. Match to protein domains PF08028, PF02771 and PF02770. Acyl-CoA dehydrogenases catalyze the alpha,beta- dehydrogenation of acyl-CoA thioesters to the corresponding trans 2,3-enoyl CoA-products with concommitant reduction of enzyme-bound FAD; acyl-CoA dehydrogenase 1805633 9793799 AARI_15780 Arthrobacter arilaitensis Re117 acyl-CoA dehydrogenase YP_003916768.1 1804485 R 861360 CDS YP_003916769.1 308177363 9795705 complement(1806095..1808794) 1 NC_014550.1 hypothetical protein 1808794 9795705 AARI_15790 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916769.1 1806095 R 861360 CDS YP_003916770.1 308177364 9795706 1809160..1809381 1 NC_014550.1 hypothetical protein 1809381 9795706 AARI_15800 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916770.1 1809160 D 861360 CDS YP_003916771.1 308177365 9793618 1809995..1810411 1 NC_014550.1 hypothetical protein 1810411 9793618 AARI_15810 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916771.1 1809995 D 861360 CDS YP_003916772.1 308177366 9793619 complement(1812011..1812622) 1 NC_014550.1 exoribonuclease specific for small oligoribonucleotides. Belongs to the oligoribonuclease family; oligoribonuclease 1812622 orn 9793619 orn Arthrobacter arilaitensis Re117 oligoribonuclease YP_003916772.1 1812011 R 861360 CDS YP_003916773.1 308177367 9794160 1812835..1814358 1 NC_014550.1 11 transmembrane helices predicted by TMHMM2.0; hypothetical protein 1814358 9794160 AARI_15830 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916773.1 1812835 D 861360 CDS YP_003916774.1 308177368 9795709 1814358..1815839 1 NC_014550.1 12 transmembrane helices predicted by TMHMM2.0; hypothetical protein 1815839 9795709 AARI_15840 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916774.1 1814358 D 861360 CDS YP_003916775.1 308177369 9795710 1815897..1817000 1 NC_014550.1 9 transmembrane helices predicted by TMHMM2.0; hypothetical protein 1817000 9795710 AARI_15850 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916775.1 1815897 D 861360 CDS YP_003916776.1 308177370 9795711 1817131..1817907 1 NC_014550.1 similar to excisionases from Mycobacterium phages; phage excisionase 1817907 9795711 AARI_15860 Arthrobacter arilaitensis Re117 phage excisionase YP_003916776.1 1817131 D 861360 CDS YP_003916777.1 308177371 9795712 1817991..1819091 1 NC_014550.1 match to PF04607. This region of unknown function is found in RelA and SpoT of Escherichia coli, and their homologues in plants and in other eubacteria; RelA/SpoT domain-containing protein 1819091 9795712 AARI_15870 Arthrobacter arilaitensis Re117 RelA/SpoT domain-containing protein YP_003916777.1 1817991 D 861360 CDS YP_003916778.1 308177372 9795713 1819284..1820885 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, () drug resistance ATPase-2 (Drug RA2) family (TC 3.A.1.121.z). ABCISSE: fused ATP-binding protein (ABC2), ART-family, ARE-subfamily (antibiotic resistance); drug resistance ATP-binding protein 1820885 9795713 AARI_15880 Arthrobacter arilaitensis Re117 drug resistance ATP-binding protein YP_003916778.1 1819284 D 861360 CDS YP_003916779.1 308177373 9795714 1820992..1821399 1 NC_014550.1 hypothetical protein 1821399 9795714 AARI_15890 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916779.1 1820992 D 861360 CDS YP_003916780.1 308177374 9795715 complement(1821473..1822384) 1 NC_014550.1 2 transmembrane helices predicted by TMHMM2.0. Signal peptide predicted by SignalP 3.0 HMM (probability: 0.652) with cleavage site probability 0.343 between position 21 and 22; hypothetical protein 1822384 9795715 AARI_15900 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916780.1 1821473 R 861360 CDS YP_003916781.1 308177375 9795716 complement(1822385..1822630) 1 NC_014550.1 hypothetical protein 1822630 9795716 AARI_15910 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916781.1 1822385 R 861360 CDS YP_003916782.1 308177376 9795717 complement(1822630..1823085) 1 NC_014550.1 2 transmembrane helices predicted by TMHMM2.0; hypothetical protein 1823085 9795717 AARI_15920 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916782.1 1822630 R 861360 CDS YP_003916783.1 308177377 9795718 1823263..1823985 1 NC_014550.1 catalyses the following reaction: (3R)-3- hydroxyacyl-ACP + NADP(+) <=> 3-oxoacyl- ACP + NADPH. Is involved in fatty acid biosynthesis; 3-oxoacyl-ACP reductase 1823985 fabG 9795718 fabG Arthrobacter arilaitensis Re117 3-oxoacyl-ACP reductase YP_003916783.1 1823263 D 861360 CDS YP_003916784.1 308177378 9793839 1824020..1824769 1 NC_014550.1 identified by match to PF00106. The short-chain dehydrogenases/reductases family (SDR) is a very large family of enzymes, most of which are known to be NAD- or NADP-dependent oxidoreductases. Possibly involved in the metabolism of lipid; short-chain dehydrogenases/reductases family protein 1824769 9793839 AARI_15940 Arthrobacter arilaitensis Re117 short-chain dehydrogenases/reductases family protein YP_003916784.1 1824020 D 861360 CDS YP_003916785.1 308177379 9795719 1825092..1825508 1 NC_014550.1 signal peptide predicted by SignalP 3.0 HMM (probability: 0.997) with cleavage site probability 0.464 between position 32 and 33; hypothetical protein 1825508 9795719 AARI_15950 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916785.1 1825092 D 861360 CDS YP_003916786.1 308177380 9795720 complement(1825639..1827387) 1 NC_014550.1 match to PF04294: VanW, VanW like protein. Family members include vancomycin resistance protein W (VanW). Genes encoding members of this family have been found in vancomycin resistance gene clusters vanB and vanG. The function of VanW is unknown; VanW-like protein 1827387 9795720 AARI_15960 Arthrobacter arilaitensis Re117 VanW-like protein YP_003916786.1 1825639 R 861360 CDS YP_003916787.1 308177381 9795721 complement(1827550..1828470) 1 NC_014550.1 responsible for the third and final step of the L- serine biosynthetic pathway; phosphoserine phosphatase 1828470 serB 9795721 serB Arthrobacter arilaitensis Re117 phosphoserine phosphatase YP_003916787.1 1827550 R 861360 CDS YP_003916788.1 308177382 9794393 1828651..1829445 1 NC_014550.1 TC 3.A.1.y.z. ABCISSE: ABC transporter, ATP-binding protein (ABC), YLU-family (unclassified systems); ABC transporter ATP-binding subunit 1829445 9794393 AARI_15980 Arthrobacter arilaitensis Re117 ABC transporter ATP-binding subunit YP_003916788.1 1828651 D 861360 CDS YP_003916789.1 308177383 9795722 1829475..1830272 1 NC_014550.1 8 transmembrane helices predicted by TMHMM2.0; hypothetical protein 1830272 9795722 AARI_15990 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916789.1 1829475 D 861360 CDS YP_003916790.1 308177384 9795723 1830277..1831110 1 NC_014550.1 identified by match to protein family PF00588: SpoU rRNA Methylase family. Possible role in rRNA modification; RNA methyltransferase 1831110 9795723 AARI_16000 Arthrobacter arilaitensis Re117 RNA methyltransferase YP_003916790.1 1830277 D 861360 CDS YP_003916791.1 308177385 9795724 1831257..1831514 1 NC_014550.1 part of the 50S ribosomal subunit; 50S ribosomal protein L31 type B 1831514 rpmE2 9795724 rpmE2 Arthrobacter arilaitensis Re117 50S ribosomal protein L31 type B YP_003916791.1 1831257 D 861360 CDS YP_003916792.1 308177386 9794337 1831652..1832707 1 NC_014550.1 catalyses the formation of an amide linkage between lipoic acid and a specific lysine residue in lipoate dependent enzymes. Lipoylation is essential for the function of several key enzymes involved in oxidative metabolism, including pyruvate dehydrogenase (E(2) domain), 2-oxoglutarate dehydrogenase (E(2) domain), the branched-chain 2-oxoacid dehydrogenases and the glycine cleavage system (H protein); lipoate--protein ligase 1832707 lplA 9794337 lplA Arthrobacter arilaitensis Re117 lipoate--protein ligase YP_003916792.1 1831652 D 861360 CDS YP_003916793.1 308177387 9794045 complement(1832720..1833475) 1 NC_014550.1 identified by match to PF00753: metallo-beta- lactamase superfamily. Apart from the beta-lactamases, a number of other proteins contain this domain. These proteins include thiolesterases, members of the glyoxalase II family, that catalyse the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid and a competence protein that is essential for natural transformation in Neisseria gonorrhoeae and could be a transporter involved in DNA uptake; metallo-beta-lactamase 1833475 9794045 AARI_16030 Arthrobacter arilaitensis Re117 metallo-beta-lactamase YP_003916793.1 1832720 R 861360 CDS YP_003916794.1 308177388 9795725 complement(1833631..1836276) 1 NC_014550.1 catalyzes the removal of single amino acids from the amino terminus of small peptides; membrane alanyl aminopeptidase 1836276 pepN 9795725 pepN Arthrobacter arilaitensis Re117 membrane alanyl aminopeptidase YP_003916794.1 1833631 R 861360 CDS YP_003916795.1 308177389 9795726 1836605..1837165 1 NC_014550.1 hypothetical protein 1837165 9795726 AARI_16060 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916795.1 1836605 D 861360 CDS YP_003916796.1 308177390 9795727 1837411..1837902 1 NC_014550.1 hypothetical protein 1837902 9795727 AARI_16070 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916796.1 1837411 D 861360 CDS YP_003916797.1 308177391 9795730 1838790..1839728 1 NC_014550.1 this family comprises several pyruvate-dependent class I aldolases that use the same catalytic step to catalyze different reactions in different pathways and includes such proteins as N-acetylneuraminate lyase, MosA protein, 5-keto-4-deoxy-glucarate dehydratase, trans-o- hydroxybenzylidenepyruvate hydratase-aldolase, trans-2- carboxybenzalpyruvate hydratase-aldolase, and 2-keto-3- deoxy- gluconate aldolase. The family is also referred to as the N-acetylneuraminate lyase family; dihydrodipicolinate synthase family protein 1839728 9795730 AARI_16100 Arthrobacter arilaitensis Re117 dihydrodipicolinate synthase family protein YP_003916797.1 1838790 D 861360 CDS YP_003916798.1 308177392 9795731 1839823..1840269 1 NC_014550.1 match to protein family PF00903: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; hypothetical protein 1840269 9795731 AARI_16110 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916798.1 1839823 D 861360 CDS YP_003916799.1 308177393 9795732 complement(1840328..1842343) 1 NC_014550.1 identified by similarity to potein SP:Q33DR0 (Arthrobacter ureafaciens). Catalyzes the oxidation of acyl-coenzyme A (acyl-CoA) thioester to the corresponding trans-2-enoyl-CoA thioester: acyl-CoA + O2 --> trans-2- enoyl-CoA + H2O2. Probably involved in beta-oxidation of fatty acids; acyl-CoA oxidase 1842343 aco 9795732 aco Arthrobacter arilaitensis Re117 acyl-CoA oxidase YP_003916799.1 1840328 R 861360 CDS YP_003916800.1 308177394 9793651 complement(1842390..1843049) 1 NC_014550.1 identified by match to PF00440: bacterial regulatory proteins, tetR family; TetR family transcriptional regulator 1843049 9793651 AARI_16130 Arthrobacter arilaitensis Re117 TetR family transcriptional regulator YP_003916800.1 1842390 R 861360 CDS YP_003916801.1 308177395 9795733 1843125..1844420 1 NC_014550.1 acetyl-CoA C-acyltransferase (also named 3-ketoacyl- CoA thiolase or thiolase I) has a broad chain-length specificity for its substrates and is involved in degradative pathways such as fatty acid beta-oxidation; acetyl-CoA C-acyltransferase 1844420 9795733 AARI_16140 Arthrobacter arilaitensis Re117 acetyl-CoA C-acyltransferase YP_003916801.1 1843125 D 861360 CDS YP_003916802.1 308177396 9795734 1844420..1845757 1 NC_014550.1 short-chain dehydrogenases/reductases family protein 1845757 9795734 AARI_16150 Arthrobacter arilaitensis Re117 short-chain dehydrogenases/reductases family protein YP_003916802.1 1844420 D 861360 CDS YP_003916803.1 308177397 9795735 1845758..1846618 1 NC_014550.1 match to PF01575 (MaoC like domain). Enoyl-CoA hydratase is involved in fatty acid metabolism. It catalyzes the hydratation of 2-trans-enoyl-CoA into 3- hydroxyacyl-CoA; enoyl-CoA hydratase 1846618 9795735 AARI_16160 Arthrobacter arilaitensis Re117 enoyl-CoA hydratase YP_003916803.1 1845758 D 861360 CDS YP_003916804.1 308177398 9795736 complement(1846682..1847866) 1 NC_014550.1 match to PF00534: Glycosyl transferases group 1. Proteins containing this domain transfer UDP, ADP, GDP or CMP linked sugars to a variety of substrates, including glycogen, fructose-6-phosphate and lipopolysaccharides. The bacterial enzymes are involved in various biosynthetic processes that include exopolysaccharide biosynthesis, lipopolysaccharide core biosynthesis and the biosynthesis of the slime polysaccaride colanic acid; glycosyl transferase family 1 1847866 9795736 AARI_16170 Arthrobacter arilaitensis Re117 glycosyl transferase family 1 YP_003916804.1 1846682 R 861360 CDS YP_003916805.1 308177399 9795737 complement(1847933..1848910) 1 NC_014550.1 prolyl aminopeptidase releases N-terminal proline from a peptide; prolyl aminopeptidase 1848910 9795737 AARI_16180 Arthrobacter arilaitensis Re117 prolyl aminopeptidase YP_003916805.1 1847933 R 861360 CDS YP_003916806.1 308177400 9795738 1849016..1849135 1 NC_014550.1 hypothetical protein 1849135 9795738 AARI_16190 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916806.1 1849016 D 861360 CDS YP_003916807.1 308177401 9793620 complement(1850231..1850875) 1 NC_014550.1 match to PF03807: NADP oxidoreductase coenzyme F420- dependent; hypothetical protein 1850875 9793620 AARI_16200 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916807.1 1850231 R 861360 CDS YP_003916808.1 308177402 9795740 complement(1850956..1852236) 1 NC_014550.1 metal ion (Mn2+-iron) transporter (Nramp) family protein (TC 2.A.55.y.z). The generalized transport reaction catalyzed by Nramp family proteins is: Me2+ (out) + H+ (out) --> Me2+ (in) + H+ (in); divalent metal ion transporter 1852236 9795740 AARI_16210 Arthrobacter arilaitensis Re117 divalent metal ion transporter YP_003916808.1 1850956 R 861360 CDS YP_003916809.1 308177403 9795741 1852479..1853147 1 NC_014550.1 response regulators are key elements in two- component signal transduction systems, which enable bacteria to sense, respond, and adapt to a wide range of environments, stressors, and growth conditions; two-component system response regulator 1853147 9795741 AARI_16220 Arthrobacter arilaitensis Re117 two-component system response regulator YP_003916809.1 1852479 D 861360 CDS YP_003916810.1 308177404 9795742 1853144..1854580 1 NC_014550.1 protein-histidine kinases are key elements in two- component signal transduction systems, which enable bacteria to sense, respond, and adapt to a wide range of environments, stressors, and growth conditions; signal transduction histidine kinase 1854580 9795742 AARI_16230 Arthrobacter arilaitensis Re117 signal transduction histidine kinase YP_003916810.1 1853144 D 861360 CDS YP_003916811.1 308177405 9795745 1855628..1856944 1 NC_014550.1 identified by match to protein family PF01546: peptidase family M20/M25/M40. This family includes a range of zinc metallopeptidases belonging to several families in the peptidase classification; zinc metallopeptidase 1856944 9795745 AARI_16260 Arthrobacter arilaitensis Re117 zinc metallopeptidase YP_003916811.1 1855628 D 861360 CDS YP_003916812.1 308177406 9795746 1856994..1858133 1 NC_014550.1 Acyl-CoA dehydrogenases catalyze the alpha,beta- dehydrogenation of acyl-CoA thioesters to the corresponding trans 2,3-enoyl CoA-products with concommitant reduction of enzyme-bound FAD. They are involved in the metabolism of lipids; acyl-CoA dehydrogenase 1858133 9795746 AARI_16270 Arthrobacter arilaitensis Re117 acyl-CoA dehydrogenase YP_003916812.1 1856994 D 861360 CDS YP_003916813.1 308177407 9795747 complement(1858136..1858369) 1 NC_014550.1 hypothetical protein 1858369 9795747 AARI_16280 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916813.1 1858136 R 861360 CDS YP_003916814.1 308177408 9795748 1858414..1858623 1 NC_014550.1 hypothetical protein 1858623 9795748 AARI_16290 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916814.1 1858414 D 861360 CDS YP_003916815.1 308177409 9795749 1858702..1859526 1 NC_014550.1 catalyses the formation of undecaprenyl phosphate from undecaprenyl diphosphate. Involved in peptidoglycan biosynthesis; undecaprenyl-diphosphatase 1859526 uppP 9795749 uppP Arthrobacter arilaitensis Re117 undecaprenyl-diphosphatase YP_003916815.1 1858702 D 861360 CDS YP_003916816.1 308177410 9794491 1859654..1860916 1 NC_014550.1 activates cysteine and transfers it to tRNA(Cys) as the first step in protein biosynthesis; cysteine--tRNA ligase 1860916 cysS 9794491 cysS Arthrobacter arilaitensis Re117 cysteine--tRNA ligase YP_003916816.1 1859654 D 861360 CDS YP_003916817.1 308177411 9793785 complement(1860950..1861858) 1 NC_014550.1 hypothetical protein 1861858 9793785 AARI_16320 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916817.1 1860950 R 861360 CDS YP_003916818.1 308177412 9795750 1861943..1862656 1 NC_014550.1 identified by match to protein family TIGR01509: HAD-superfamily hydrolase, subfamily IA, variant 3; match to protein family PF00702: haloacid dehalogenase-like hydrolase; hydrolase 1862656 9795750 AARI_16330 Arthrobacter arilaitensis Re117 hydrolase YP_003916818.1 1861943 D 861360 CDS YP_003916819.1 308177413 9795751 1862653..1863780 1 NC_014550.1 match to protein family PF02163: Peptidase family M50. Match to PS00142 pattern: neutral zinc metallopeptidases, zinc-binding region signature. 6 transmembrane helices predicted by TMHMM2.0; zinc metallopeptidase 1863780 9795751 AARI_16340 Arthrobacter arilaitensis Re117 zinc metallopeptidase YP_003916819.1 1862653 D 861360 CDS YP_003916820.1 308177414 9795752 1863823..1864884 1 NC_014550.1 identified by match to protein family PF08704: GCD14, tRNA methyltransferase complex GCD14 subunit. tRNA (adenine-N(1)-)-methyltransferase catalyses the following reaction: S-adenosyl-L-methionine + tRNA <=> S-adenosyl-L- homocysteine + tRNA containing N(1)-methyladenine. The enzymes from different sources are specific for different adenine residues in tRNA; tRNA (adenine-N(1)-)-methyltransferase 1864884 9795752 AARI_16350 Arthrobacter arilaitensis Re117 tRNA (adenine-N(1)-)-methyltransferase YP_003916820.1 1863823 D 861360 CDS YP_003916821.1 308177415 9795753 1864985..1866742 1 NC_014550.1 COG1222: RPT1, ATP-dependent 26S proteasome regulatory subunit. Proteasomes are large protein complexes, which main function is to degrade unneeded or damaged proteins; ATP-dependent 26S proteasome regulatory subunit 1866742 9795753 AARI_16360 Arthrobacter arilaitensis Re117 ATP-dependent 26S proteasome regulatory subunit YP_003916821.1 1864985 D 861360 CDS YP_003916822.1 308177416 9795754 1866739..1868358 1 NC_014550.1 identified by match to protein family PF03136: DUF245, proteasome component. Proteasomes are large protein complexes, which main function is to degrade unneeded or damaged proteins; proteasome component 1868358 9795754 AARI_16370 Arthrobacter arilaitensis Re117 proteasome component YP_003916822.1 1866739 D 861360 CDS YP_003916823.1 308177417 9795755 1868425..1868610 1 NC_014550.1 hypothetical protein 1868610 9795755 AARI_16380 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916823.1 1868425 D 861360 CDS YP_003916824.1 308177418 9795756 1868689..1870065 1 NC_014550.1 identified by match to protein family PF03136: DUF245, proteasome component. Proteasomes are large protein complexes, which main function is to degrade unneeded or damaged proteins; proteasome component 1870065 9795756 AARI_16390 Arthrobacter arilaitensis Re117 proteasome component YP_003916824.1 1868689 D 861360 CDS YP_003916825.1 308177419 9795757 1870184..1871119 1 NC_014550.1 identified by match to protein family PF00254: FKBP- type peptidyl-prolyl cis-trans isomerase. Peptidylprolyl isomerase is an enzyme that accelerates protein folding by catalyzing the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Signal peptide predicted by SignalP 3.0 HMM (probability: 1) with cleavage site probability 0.529 between position 27 and 28; peptidylprolyl isomerase 1871119 9795757 AARI_16400 Arthrobacter arilaitensis Re117 peptidylprolyl isomerase YP_003916825.1 1870184 D 861360 CDS YP_003916826.1 308177420 9795758 1871136..1871531 1 NC_014550.1 identified by match to protein family PF00254: FKBP- type peptidyl-prolyl cis-trans isomerase. Peptidylprolyl isomerase is an enzyme that accelerates protein folding by catalyzing the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; peptidylprolyl isomerase 1871531 9795758 AARI_16410 Arthrobacter arilaitensis Re117 peptidylprolyl isomerase YP_003916826.1 1871136 D 861360 CDS YP_003916827.1 308177421 9795759 1871625..1873628 1 NC_014550.1 transcriptional regulator 1873628 9795759 AARI_16420 Arthrobacter arilaitensis Re117 transcriptional regulator YP_003916827.1 1871625 D 861360 CDS YP_003916828.1 308177422 9795760 1873632..1873991 1 NC_014550.1 signal peptide predicted by SignalP 3.0 HMM (probability: 0.673) with cleavage site probability 0.443 between position 23 and 24; hypothetical protein 1873991 9795760 AARI_16430 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916828.1 1873632 D 861360 CDS YP_003916829.1 308177423 9795761 1874024..1874239 1 NC_014550.1 identified by match to protein family TIGR01411: twin-arginine translocation protein TatA/E. The twin- arginine translocation system is a Sec-independent exporter for folded proteins, often with a redox cofactor already bound, across the bacterial inner membrane; twin-arginine translocation protein TatA/E 1874239 tatA 9795761 tatA Arthrobacter arilaitensis Re117 twin-arginine translocation protein TatA/E YP_003916829.1 1874024 D 861360 CDS YP_003916830.1 308177424 9794425 1874249..1875118 1 NC_014550.1 identified by match to protein family PF00902: Sec- independent protein translocase protein (TatC). The twin- arginine translocation system is a Sec-independent exporter for folded proteins, often with a redox cofactor already bound, across the bacterial inner membrane; twin-arginine translocation protein TatC 1875118 tatC 9794425 tatC Arthrobacter arilaitensis Re117 twin-arginine translocation protein TatC YP_003916830.1 1874249 D 861360 CDS YP_003916831.1 308177425 9794427 1875147..1877930 1 NC_014550.1 DEAD box helicase. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression; ATP-dependent RNA helicase 1877930 9794427 AARI_16460 Arthrobacter arilaitensis Re117 ATP-dependent RNA helicase YP_003916831.1 1875147 D 861360 CDS YP_003916832.1 308177426 9795762 1877987..1879594 1 NC_014550.1 identified by match to protein family PF07969: amidohydrolase family; amidohydrolase family protein 1879594 9795762 AARI_16470 Arthrobacter arilaitensis Re117 amidohydrolase family protein YP_003916832.1 1877987 D 861360 CDS YP_003916833.1 308177427 9795763 1880009..1880737 1 NC_014550.1 match to PF00535: glycosyl transferase family 2. This domain is found in a diverse family of glycosyl transferases that transfer the sugar from UDP-glucose, UDP- N-acetyl-galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids; glycosyl transferase family 2 1880737 9795763 AARI_16480 Arthrobacter arilaitensis Re117 glycosyl transferase family 2 YP_003916833.1 1880009 D 861360 CDS YP_003916834.1 308177428 9795764 complement(1880951..1881298) 1 NC_014550.1 hypothetical protein 1881298 9795764 AARI_16490 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916834.1 1880951 R 861360 CDS YP_003916835.1 308177429 9795765 complement(1881483..1882421) 1 NC_014550.1 identified by match to protein family PF01145. The band 7 protein is an integral membrane protein which is thought to regulate cation conductance. A variety of proteins belong to this family; band 7 family protein 1882421 9795765 AARI_16500 Arthrobacter arilaitensis Re117 band 7 family protein YP_003916835.1 1881483 R 861360 CDS YP_003916836.1 308177430 9795766 complement(1882479..1882955) 1 NC_014550.1 3 transmembrane helices predicted by TMHMM2.0; hypothetical protein 1882955 9795766 AARI_16510 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916836.1 1882479 R 861360 CDS YP_003916837.1 308177431 9795767 complement(1883060..1883911) 1 NC_014550.1 rRNA methyltransferase catalyzes the following reaction: S-adenosyl-L-methionine + rRNA => S-adenosyl-L- homocysteine + rRNA containing N(1)-methylguanine. It is required for translation and cell growth; rRNA (guanine-N(1)-)-methyltransferase 1883911 rrmA 9795767 rrmA Arthrobacter arilaitensis Re117 rRNA (guanine-N(1)-)-methyltransferase YP_003916837.1 1883060 R 861360 CDS YP_003916838.1 308177432 9794369 complement(1883911..1884552) 1 NC_014550.1 involved in polypeptide synthesis by removal of the formyl-group from methionine in growing polypeptides; peptide deformylase 1884552 def 9794369 def Arthrobacter arilaitensis Re117 peptide deformylase YP_003916838.1 1883911 R 861360 CDS YP_003916839.1 308177433 9793800 complement(1884549..1885601) 1 NC_014550.1 identified by match to protein family PF03969: AFG1_ATPase, AFG1-like ATPase; ATPase 1885601 9793800 AARI_16540 Arthrobacter arilaitensis Re117 ATPase YP_003916839.1 1884549 R 861360 CDS YP_003916840.1 308177434 9795768 1885924..1886271 1 NC_014550.1 identified by match to PF01022. ArsR-family transcriptional regulators include several proteins that appear to dissociate from DNA in the presence of metal ions; ArsR family transcriptional regulator 1886271 9795768 AARI_16550 Arthrobacter arilaitensis Re117 ArsR family transcriptional regulator YP_003916840.1 1885924 D 861360 CDS YP_003916841.1 308177435 9795769 1886467..1886937 1 NC_014550.1 match to protein family PF03969: activator of Hsp90 ATPase homolog 1-like protein; hypothetical protein 1886937 9795769 AARI_16560 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916841.1 1886467 D 861360 CDS YP_003916842.1 308177436 9795770 1887275..1887736 1 NC_014550.1 4 transmembrane helices predicted by TMHMM2.0; hypothetical protein 1887736 9795770 AARI_16570 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916842.1 1887275 D 861360 CDS YP_003916843.1 308177437 9795771 complement(1887870..1888844) 1 NC_014550.1 identified by match to protein family PF01758. Bile acid:Na+ symporter (BASS) family (TC 2.A.28.y.z): these symporters exhibit broad specificity, taking up a variety of non bile organic compounds as well as taurocholate and other bile salts; sodium-dependent transporter 1888844 9795771 AARI_16580 Arthrobacter arilaitensis Re117 sodium-dependent transporter YP_003916843.1 1887870 R 861360 CDS YP_003916844.1 308177438 9795772 1888989..1889363 1 NC_014550.1 4 transmembrane helices predicted by TMHMM2.0; hypothetical protein 1889363 9795772 AARI_16590 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916844.1 1888989 D 861360 CDS YP_003916845.1 308177439 9795773 complement(1889352..1889894) 1 NC_014550.1 4 transmembrane helices predicted by TMHMM2.0; hypothetical protein 1889894 9795773 AARI_16600 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916845.1 1889352 R 861360 CDS YP_003916846.1 308177440 9795774 complement(1889895..1890491) 1 NC_014550.1 hypothetical protein 1890491 9795774 AARI_16610 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916846.1 1889895 R 861360 CDS YP_003916847.1 308177441 9795775 1890654..1890938 1 NC_014550.1 identified by match to protein family PF01037: AsnC_trans_reg, AsnC family; AsnC/Lrp family transcriptional regulator 1890938 9795775 AARI_16620 Arthrobacter arilaitensis Re117 AsnC/Lrp family transcriptional regulator YP_003916847.1 1890654 D 861360 CDS YP_003916848.1 308177442 9795776 complement(1891026..1892045) 1 NC_014550.1 involved in tryptophane biosynthesis; anthranilate phosphoribosyltransferase 1892045 trpD 9795776 trpD Arthrobacter arilaitensis Re117 anthranilate phosphoribosyltransferase YP_003916848.1 1891026 R 861360 CDS YP_003916849.1 308177443 9794469 1892381..1893019 1 NC_014550.1 in Corynebacterium glutamicum, a cytochrome aa3 terminal oxidase (EC 1.9.3.1) receives electrons from a bc1 complex (EC 1.10.2.2). The bc1 complex is encoded by qcrA (Rieske iron-sulfur protein), qcrB (cytochrome B) and qcrC (cytochrome c1). Cytochrome aa3 is composed of subunits I (ctaD), II (ctaC), III (ctaE) and IV (ctaF). These subunits form the cytochrome bc1-aa3 supercomplex; cytochrome aa3 subunit 3 1893019 ctaE 9794469 ctaE Arthrobacter arilaitensis Re117 cytochrome aa3 subunit 3 YP_003916849.1 1892381 D 861360 CDS YP_003916850.1 308177444 9793766 1893096..1893890 1 NC_014550.1 in Corynebacterium glutamicum, a cytochrome aa3 terminal oxidase (EC 1.9.3.1) receives electrons from a bc1 complex (EC 1.10.2.2). The bc1 complex is encoded by qcrA (Rieske iron-sulfur protein), qcrB (cytochrome B) and qcrC (cytochrome c1). Cytochrome aa3 is composed of subunits I (ctaD), II (ctaC), III (ctaE) and IV (ctaF). These subunits form the cytochrome bc1-aa3 supercomplex; cytochrome bc1 complex cytochrome c1 subunit 1893890 qcrC 9793766 qcrC Arthrobacter arilaitensis Re117 cytochrome bc1 complex cytochrome c1 subunit YP_003916850.1 1893096 D 861360 CDS YP_003916851.1 308177445 9794277 1893961..1895010 1 NC_014550.1 in Corynebacterium glutamicum, a cytochrome aa3 terminal oxidase (EC 1.9.3.1) receives electrons from a bc1 complex (EC 1.10.2.2). The bc1 complex is encoded by qcrA (Rieske iron-sulfur protein), qcrB (cytochrome B) and qcrC (cytochrome c1). Cytochrome aa3 is composed of subunits I (ctaD), II (ctaC), III (ctaE) and IV (ctaF). These subunits form the cytochrome bc1-aa3 supercomplex; cytochrome bc1 complex iron sulfur subunit 1895010 qcrA 9794277 qcrA Arthrobacter arilaitensis Re117 cytochrome bc1 complex iron sulfur subunit YP_003916851.1 1893961 D 861360 CDS YP_003916852.1 308177446 9794275 1895013..1896683 1 NC_014550.1 in Corynebacterium glutamicum, a cytochrome aa3 terminal oxidase (EC 1.9.3.1) receives electrons from a bc1 complex (EC 1.10.2.2). The bc1 complex is encoded by qcrA (Rieske iron-sulfur protein), qcrB (cytochrome B) and qcrC (cytochrome c1). Cytochrome aa3 is composed of subunits I (ctaD), II (ctaC), III (ctaE) and IV (ctaF). These subunits form the cytochrome bc1-aa3 supercomplex; cytochrome bc1 complex cytochrome b subunit 1896683 qcrB 9794275 qcrB Arthrobacter arilaitensis Re117 cytochrome bc1 complex cytochrome b subunit YP_003916852.1 1895013 D 861360 CDS YP_003916853.1 308177447 9794276 complement(1897400..1898182) 1 NC_014550.1 identified by match to protein family PF00392. This family of regulatory proteins consists of the N-terminal HTH region of GntR-like bacterial transcription factors. At the C-terminus there is usually an effector- binding/oligomerisation domain. The GntR-like proteins can be divided into six sub-families: MocR, YtrR, FadR, AraR, HutC and PlmA. Many of these proteins have been shown experimentally to be autoregulatory, enabling the prediction of operator sites and the discovery of cis/trans relationships; GntR family transcriptional regulator 1898182 9794276 AARI_16680 Arthrobacter arilaitensis Re117 GntR family transcriptional regulator YP_003916853.1 1897400 R 861360 CDS YP_003916854.1 308177448 9795777 complement(1898296..1898697) 1 NC_014550.1 in Corynebacterium glutamicum, a cytochrome aa3 terminal oxidase (EC 1.9.3.1) receives electrons from a bc1 complex (EC 1.10.2.2). The bc1 complex is encoded by qcrA (Rieske iron-sulfur protein), qcrB (cytochrome B) and qcrC (cytochrome c1). Cytochrome aa3 is composed of subunits I (ctaD), II (ctaC), III (ctaE) and IV (ctaF). These subunits form the cytochrome bc1-aa3 supercomplex; cytochrome aa3 subunit 4 1898697 ctaF 9795777 ctaF Arthrobacter arilaitensis Re117 cytochrome aa3 subunit 4 YP_003916854.1 1898296 R 861360 CDS YP_003916855.1 308177449 9793767 complement(1898700..1900418) 1 NC_014550.1 in Corynebacterium glutamicum, a cytochrome aa3 terminal oxidase (EC 1.9.3.1) receives electrons from a bc1 complex (EC 1.10.2.2). The bc1 complex is encoded by qcrA (Rieske iron-sulfur protein), qcrB (cytochrome B) and qcrC (cytochrome c1). Cytochrome aa3 is composed of subunits I (ctaD), II (ctaC), III (ctaE) and IV (ctaF). These subunits form the cytochrome bc1-aa3 supercomplex; cytochrome aa3 subunit 1 1900418 ctaD 9793767 ctaD Arthrobacter arilaitensis Re117 cytochrome aa3 subunit 1 YP_003916855.1 1898700 R 861360 CDS YP_003916856.1 308177450 9793765 complement(1900421..1901344) 1 NC_014550.1 in Corynebacterium glutamicum, a cytochrome aa3 terminal oxidase (EC 1.9.3.1) receives electrons from a bc1 complex (EC 1.10.2.2). The bc1 complex is encoded by qcrA (Rieske iron-sulfur protein), qcrB (cytochrome B) and qcrC (cytochrome c1). Cytochrome aa3 is composed of subunits I (ctaD), II (ctaC), III (ctaE) and IV (ctaF). These subunits form the cytochrome bc1-aa3 supercomplex; cytochrome aa3 subunit 2 1901344 ctaC 9793765 ctaC Arthrobacter arilaitensis Re117 cytochrome aa3 subunit 2 YP_003916856.1 1900421 R 861360 CDS YP_003916857.1 308177451 9793764 complement(1901517..1901891) 1 NC_014550.1 identified by match to protein family TIGR00049; iron-sulfur cluster assembly accessory protein 1901891 9793764 AARI_16720 Arthrobacter arilaitensis Re117 iron-sulfur cluster assembly accessory protein YP_003916857.1 1901517 R 861360 CDS YP_003916858.1 308177452 9795778 complement(1902026..1903435) 1 NC_014550.1 identified by match to protein family PF01546: peptidase family M20/M25/M40. This family includes a range of zinc metallopeptidases belonging to several families in the peptidase classification; zinc metallopeptidase 1903435 9795778 AARI_16730 Arthrobacter arilaitensis Re117 zinc metallopeptidase YP_003916858.1 1902026 R 861360 CDS YP_003916859.1 308177453 9795779 1903505..1904098 1 NC_014550.1 2 transmembrane helices predicted by TMHMM2.0; hypothetical protein 1904098 9795779 AARI_16740 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916859.1 1903505 D 861360 CDS YP_003916860.1 308177454 9795780 complement(1904466..1905530) 1 NC_014550.1 catalyzes the fourth step in the de novo biosynthesis of pyrimidine, the conversion of dihydroorotate into orotate; dihydroorotate oxidase 1905530 pyrD 9795780 pyrD Arthrobacter arilaitensis Re117 dihydroorotate oxidase YP_003916860.1 1904466 R 861360 CDS YP_003916861.1 308177455 9794267 1905591..1906628 1 NC_014550.1 match to PF00561: alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes; hydrolase 1906628 9794267 AARI_16760 Arthrobacter arilaitensis Re117 hydrolase YP_003916861.1 1905591 D 861360 CDS YP_003916862.1 308177456 9795781 complement(1906635..1907441) 1 NC_014550.1 generates undecaprenyl pyrophosphate (UPP) from isopentenyl pyrophosphate (IPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide; di-trans,poly-cis-decaprenylcistransferase 1907441 uppS2 9795781 uppS2 Arthrobacter arilaitensis Re117 di-trans,poly-cis-decaprenylcistransferase YP_003916862.1 1906635 R 861360 CDS YP_003916863.1 308177457 9794493 complement(1907438..1908187) 1 NC_014550.1 involved in DNA repair and recF pathway recombination; DNA repair protein RecO 1908187 recO 9794493 recO Arthrobacter arilaitensis Re117 DNA repair protein RecO YP_003916863.1 1907438 R 861360 CDS YP_003916864.1 308177458 9794290 complement(1908291..1910003) 1 NC_014550.1 catalyzes the first step in the biosynthesis of leucine, the condensation of acetyl-CoA and 2- oxoisovalerate to form 2-isopropylmalate; 2-isopropylmalate synthase 1910003 leuA 9794290 leuA Arthrobacter arilaitensis Re117 2-isopropylmalate synthase YP_003916864.1 1908291 R 861360 CDS YP_003916865.1 308177459 9794031 1910323..1911495 1 NC_014550.1 FAD-dependent oxidoreductase 1911495 9794031 AARI_16800 Arthrobacter arilaitensis Re117 FAD-dependent oxidoreductase YP_003916865.1 1910323 D 861360 CDS YP_003916866.1 308177460 9795782 complement(1911576..1912538) 1 NC_014550.1 in Escherichia coli, the protein Era is involved in 16S rRNA maturation and ribosome assembly; GTP-binding protein Era 1912538 era 9795782 era Arthrobacter arilaitensis Re117 GTP-binding protein Era YP_003916866.1 1911576 R 861360 CDS YP_003916867.1 308177461 9793836 complement(1912531..1913817) 1 NC_014550.1 possible transporter. Match to PF00571 (CBS domain pair); CBS domain-containing transporter 1913817 9793836 AARI_16820 Arthrobacter arilaitensis Re117 CBS domain-containing transporter YP_003916867.1 1912531 R 861360 CDS YP_003916868.1 308177462 9795783 complement(1913822..1914295) 1 NC_014550.1 metalloprotease 1914295 9795783 AARI_16830 Arthrobacter arilaitensis Re117 metalloprotease YP_003916868.1 1913822 R 861360 CDS YP_003916869.1 308177463 9795784 complement(1914292..1915320) 1 NC_014550.1 identified by match to protein family PF02562: PhoH, PhoH-like protein. PhoH is a cytoplasmic protein and predicted ATPase that is induced by phosphate starvation; PhoH-like protein 1915320 9795784 AARI_16840 Arthrobacter arilaitensis Re117 PhoH-like protein YP_003916869.1 1914292 R 861360 CDS YP_003916870.1 308177464 9795785 1915508..1916539 1 NC_014550.1 hypothetical protein 1916539 9795785 AARI_16850 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916870.1 1915508 D 861360 CDS YP_003916871.1 308177465 9795786 complement(1916835..1917608) 1 NC_014550.1 hypothetical protein 1917608 9795786 AARI_16860 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916871.1 1916835 R 861360 CDS YP_003916872.1 308177466 9795787 complement(1917611..1918735) 1 NC_014550.1 involved in protein folding and renaturation after stress; chaperone protein DnaJ 1918735 dnaJ 9795787 dnaJ Arthrobacter arilaitensis Re117 chaperone protein DnaJ YP_003916872.1 1917611 R 861360 CDS YP_003916873.1 308177467 9793825 complement(1918802..1919815) 1 NC_014550.1 match to protein family PF01628: HrcA protein C terminal domain. HrcA is found to negatively regulate the transcription of heat shock genes; heat-inducible transcription repressor HrcA 1919815 hrcA 9793825 hrcA Arthrobacter arilaitensis Re117 heat-inducible transcription repressor HrcA YP_003916873.1 1918802 R 861360 CDS YP_003916874.1 308177468 9793976 1919943..1920815 1 NC_014550.1 hypothetical protein 1920815 9793976 AARI_16890 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916874.1 1919943 D 861360 CDS YP_003916875.1 308177469 9795788 1920904..1921305 1 NC_014550.1 3 transmembrane helices predicted by TMHMM2.0; hypothetical protein 1921305 9795788 AARI_16900 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916875.1 1920904 D 861360 CDS YP_003916876.1 308177470 9795789 complement(1921322..1922551) 1 NC_014550.1 catalyzes the oxidative decarboxylation of coproporphyrinogen III into protoporphyrinogen IX, a common step in the pathway for the biosynthesis of porphyrins such as heme, chlorophyll or cobalamin: coproporphyrinogen-III + O(2) + 2 H(+) <=> protoporphyrinogen-IX + 2 CO(2) + 2 H(2)O; coproporphyrinogen oxidase 1922551 hemF 9795789 hemF Arthrobacter arilaitensis Re117 coproporphyrinogen oxidase YP_003916876.1 1921322 R 861360 CDS YP_003916877.1 308177471 9793954 complement(1922552..1924390) 1 NC_014550.1 the extremely conserved LepA protein, present in all bacteria and mitochondria, is an elongation factor required for accurate and efficient protein synthesis; GTP-binding elongation factor LepA 1924390 lepA 9793954 lepA Arthrobacter arilaitensis Re117 GTP-binding elongation factor LepA YP_003916877.1 1922552 R 861360 CDS YP_003916878.1 308177472 9794029 1924512..1925081 1 NC_014550.1 hypothetical protein 1925081 9794029 AARI_16930 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916878.1 1924512 D 861360 CDS YP_003916879.1 308177473 9795790 1925252..1925512 1 NC_014550.1 Binds directly to 16S ribosomal RNA; 30S ribosomal protein S20 1925512 rpsT 9795790 rpsT Arthrobacter arilaitensis Re117 30S ribosomal protein S20 YP_003916879.1 1925252 D 861360 CDS YP_003916880.1 308177474 9794367 complement(1925667..1926659) 1 NC_014550.1 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The beta chain is required for initiation of replication once it is clamped onto DNA. DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII complex. PolIII associates with the gamma complex (composed of gamma, delta, delta prime, psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex; DNA polymerase III subunit delta 1926659 holA 9794367 holA Arthrobacter arilaitensis Re117 DNA polymerase III subunit delta YP_003916880.1 1925667 R 861360 CDS YP_003916881.1 308177475 9793970 complement(1926694..1928961) 1 NC_014550.1 identified by match to protein family PF03772, some members of this family have been shown to be essential for bacterial competence in uptake of extracellular DNA. 10 transmembrane helices predicted by TMHMM2.0; competence protein 1928961 9793970 AARI_16960 Arthrobacter arilaitensis Re117 competence protein YP_003916881.1 1926694 R 861360 CDS YP_003916882.1 308177476 9795791 complement(1928958..1929605) 1 NC_014550.1 helix-hairpin-helix DNA-binding domain. The HhH motif is an around 20 amino acids domain present in prokaryotic and eukaryotic non-sequence-specific DNA binding proteins; DNA uptake protein 1929605 9795791 AARI_16970 Arthrobacter arilaitensis Re117 DNA uptake protein YP_003916882.1 1928958 R 861360 CDS YP_003916883.1 308177477 9795792 complement(1929621..1930559) 1 NC_014550.1 identified by match to protein family PF02645: uncharacterised protein, DegV family COG1307. The structure of this protein revealed a bound fatty-acid molecule in a pocket between the two protein domains. The structure indicates that this family has the molecular function of fatty-acid binding and may play a role in the cellular functions of fatty acid transport or metabolism; DegV family protein 1930559 9795792 AARI_16980 Arthrobacter arilaitensis Re117 DegV family protein YP_003916883.1 1929621 R 861360 CDS YP_003916884.1 308177478 9795793 complement(1930569..1933058) 1 NC_014550.1 leucine-tRNA ligase 1933058 leuS 9795793 leuS Arthrobacter arilaitensis Re117 leucine-tRNA ligase YP_003916884.1 1930569 R 861360 CDS YP_003916885.1 308177479 9794035 1933347..1935197 1 NC_014550.1 match to HNH endonuclease signature (cd00085); HNH endonuclease domain-containing protein 1935197 9794035 AARI_17000 Arthrobacter arilaitensis Re117 HNH endonuclease domain-containing protein YP_003916885.1 1933347 D 861360 CDS YP_003916886.1 308177480 9795794 complement(1935288..1936808) 1 NC_014550.1 catalyzes the Mg-ATP-dependent phosphorylation of glycerol to yield glycerol 3-phosphate. Key enzyme of glycerol metabolism in bacteria, phosphorylation of glycerol prevents diffusion through the membrane; glycerol kinase 1936808 glpK 9795794 glpK Arthrobacter arilaitensis Re117 glycerol kinase YP_003916886.1 1935288 R 861360 CDS YP_003916887.1 308177481 9793911 complement(1936826..1937554) 1 NC_014550.1 glycerol facilitators function as solute nonspecific channels, and may transport glycerol, dihydroxyacetone, propanediol, urea and other small neutral molecules in physiologically important processes. Belongs to the the Major Intrinsic Protein (MIP) family (TC 1.A.8.y.z); glycerol uptake facilitator protein 1937554 glpF 9793911 glpF Arthrobacter arilaitensis Re117 glycerol uptake facilitator protein YP_003916887.1 1936826 R 861360 CDS YP_003916888.1 308177482 9793910 complement(1937614..1939293) 1 NC_014550.1 catalyzes the following reaction: sn-glycerol-3- phosphate + acceptor = glycerone phosphate + reduced acceptor. In bacteria, it is associated with the utilization of glycerol coupled to respiration; glycerol-3-phosphate dehydrogenase 1939293 glpD 9793910 glpD Arthrobacter arilaitensis Re117 glycerol-3-phosphate dehydrogenase YP_003916888.1 1937614 R 861360 CDS YP_003916889.1 308177483 9793909 1939400..1940407 1 NC_014550.1 transcriptional regulator 1940407 9793909 AARI_17040 Arthrobacter arilaitensis Re117 transcriptional regulator YP_003916889.1 1939400 D 861360 CDS YP_003916890.1 308177484 9795795 1940417..1941289 1 NC_014550.1 match to PS00120 pattern: lipases, serine active site; lipase/esterase 1941289 9795795 AARI_17050 Arthrobacter arilaitensis Re117 lipase/esterase YP_003916890.1 1940417 D 861360 CDS YP_003916891.1 308177485 9795796 complement(1941286..1943247) 1 NC_014550.1 formation of the primosome proceeds with the subsequent actions of dnaB, dnaC, dnaT and primase. PriA then functions as a helicase within the primosome; primosomal protein PriA 1943247 priA 9795796 priA Arthrobacter arilaitensis Re117 primosomal protein PriA YP_003916891.1 1941286 R 861360 CDS YP_003916892.1 308177486 9794222 complement(1943257..1944462) 1 NC_014550.1 catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. AdoMet is an important methyl donor for transmethylation and is also the propylamino donor in polyamine biosynthesis; methionine adenosyltransferase 1944462 metK 9794222 metK Arthrobacter arilaitensis Re117 methionine adenosyltransferase YP_003916892.1 1943257 R 861360 CDS YP_003916893.1 308177487 9794074 complement(1944563..1945765) 1 NC_014550.1 catalyzes two steps in the biosynthesis of coenzyme A: EC 6.3.2.5 conjugues cysteine to 4-phosphopantothenate to form 4-phosphopantothenoylcysteine (CTP + (R)-4- phosphopantothenate + L-cysteine = CMP + PPi + N-((R)-4- phosphopantothenoyl)-L-cysteine), EC 4.1.1.36 decarboxylates 4-phosphopantothenoylcysteine to form 4- phosphopantotheine (N-((R)-4-phosphopantothenoyl)-L- cysteine = pantotheine 4-phosphate + CO2); bifunctional phosphopantothenate-cysteine ligase/phosphopantothenoylcysteine decarboxylase 1945765 coaBC 9794074 coaBC Arthrobacter arilaitensis Re117 bifunctional phosphopantothenate-cysteine ligase/phosphopantothenoylcysteine decarboxylase YP_003916893.1 1944563 R 861360 CDS YP_003916894.1 308177488 9793748 complement(1945863..1946123) 1 NC_014550.1 DNA-directed RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; DNA-directed RNA polymerase omega chain 1946123 rpoZ 9793748 rpoZ Arthrobacter arilaitensis Re117 DNA-directed RNA polymerase omega chain YP_003916894.1 1945863 R 861360 CDS YP_003916895.1 308177489 9794347 complement(1946132..1946698) 1 NC_014550.1 catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine diphosphate (GDP). It plays an essential role in the biosynthesis of guanosine triphosphate (GTP); guanylate kinase 1946698 gmk 9794347 gmk Arthrobacter arilaitensis Re117 guanylate kinase YP_003916895.1 1946132 R 861360 CDS YP_003916896.1 308177490 9793929 complement(1946702..1947037) 1 NC_014550.1 match to SM00278 (Helix-hairpin-helix DNA-binding motif, class 1); DNA-binding protein 1947037 9793929 AARI_17110 Arthrobacter arilaitensis Re117 DNA-binding protein YP_003916896.1 1946702 R 861360 CDS YP_003916897.1 308177491 9795797 complement(1947184..1948026) 1 NC_014550.1 decarboxylates orotidine-5-phosphate to form uridine 5-phosphate (UMP). Involved in pyrimidine biosynthesis; orotidine-5'-phosphate decarboxylase 1948026 pyrF 9795797 pyrF Arthrobacter arilaitensis Re117 orotidine-5'-phosphate decarboxylase YP_003916897.1 1947184 R 861360 CDS YP_003916898.1 308177492 9794271 complement(1948019..1951297) 1 NC_014550.1 carbamoyl-phosphate synthase is involved in both arginine and pyrimidine biosynthesis and catalyzes the ATP- dependent formation of carbamoyl-phosphate from glutamine and carbon dioxide. In bacteria it is composed of two subunits: a large chain (gene carB) and a small chain (gene carA); carbamoyl-phosphate synthase (glutamine-hydrolyzing) large subunit 1951297 carB 9794271 carB Arthrobacter arilaitensis Re117 carbamoyl-phosphate synthase (glutamine-hydrolyzing) large subunit YP_003916898.1 1948019 R 861360 CDS YP_003916899.1 308177493 9793726 complement(1951297..1952466) 1 NC_014550.1 carbamoyl-phosphate synthase is involved in both arginine and pyrimidine biosynthesis and catalyzes the ATP- dependent formation of carbamoyl-phosphate from glutamine and carbon dioxide. In bacteria it is composed of two subunits: a large chain (gene carB) and a small chain (gene carA); carbamoyl-phosphate synthase (glutamine-hydrolyzing) small subunit 1952466 carA 9793726 carA Arthrobacter arilaitensis Re117 carbamoyl-phosphate synthase (glutamine-hydrolyzing) small subunit YP_003916899.1 1951297 R 861360 CDS YP_003916900.1 308177494 9793725 complement(1952467..1952973) 1 NC_014550.1 1 transmembrane helice predicted by TMHMM2.0; hypothetical protein 1952973 9793725 AARI_17150 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916900.1 1952467 R 861360 CDS YP_003916901.1 308177495 9795798 complement(1952966..1954270) 1 NC_014550.1 catalyzes the third step in the de novo biosynthesis of pyrimidine, the conversion of N-carbamoyl- L-aspartate into dihydroorotate; dihydroorotase 1954270 pyrC 9795798 pyrC Arthrobacter arilaitensis Re117 dihydroorotase YP_003916901.1 1952966 R 861360 CDS YP_003916902.1 308177496 9794265 complement(1954282..1955244) 1 NC_014550.1 catalyzes the conversion of aspartate and carbamoyl phosphate to carbamoylaspartate, the second step in the de novo biosynthesis of pyrimidine; aspartate carbamoyltransferase 1955244 pyrB 9794265 pyrB Arthrobacter arilaitensis Re117 aspartate carbamoyltransferase YP_003916902.1 1954282 R 861360 CDS YP_003916903.1 308177497 9794264 complement(1955241..1955810) 1 NC_014550.1 regulates pyrimidine biosynthesis by binding to the mRNA of the pyr genes. Has also a uracil phosphoribosyltransferase activity: formation of UMP and diphosphate from uracil and 5-phospho-alpha-D-ribose 1- diphosphate; bifunctional protein pyrR 1955810 pyrR 9794264 pyrR Arthrobacter arilaitensis Re117 bifunctional protein pyrR YP_003916903.1 1955241 R 861360 CDS YP_003916904.1 308177498 9794274 1955997..1956479 1 NC_014550.1 signal peptide predicted by SignalP 3.0 HMM (probability: 0.881) with cleavage site probability 0.567 between position 37 and 38; hypothetical protein 1956479 9794274 AARI_17190 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916904.1 1955997 D 861360 CDS YP_003916905.1 308177499 9795799 complement(1956286..1956636) 1 NC_014550.1 hypothetical protein 1956636 9795799 AARI_17200 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916905.1 1956286 R 861360 CDS YP_003916906.1 308177500 9795800 complement(1956748..1957158) 1 NC_014550.1 regulates rRNA biosynthesis by transcriptional antitermination; transcription antitermination factor NusB 1957158 nusB 9795800 nusB Arthrobacter arilaitensis Re117 transcription antitermination factor NusB YP_003916906.1 1956748 R 861360 CDS YP_003916907.1 308177501 9794154 complement(1957158..1957718) 1 NC_014550.1 required for efficient translation; elongation factor P 1957718 efp 9794154 efp Arthrobacter arilaitensis Re117 elongation factor P YP_003916907.1 1957158 R 861360 CDS YP_003916908.1 308177502 9793833 complement(1957829..1958359) 1 NC_014550.1 hypothetical protein 1958359 9793833 AARI_17230 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916908.1 1957829 R 861360 CDS YP_003916909.1 308177503 9795801 complement(1958364..1959455) 1 NC_014550.1 involved in phenylalanine, tyrosine and tryptophan biosynthesis; 3-dehydroquinate synthase 1959455 aroB 9795801 aroB Arthrobacter arilaitensis Re117 3-dehydroquinate synthase YP_003916909.1 1958364 R 861360 CDS YP_003916910.1 308177504 9793683 complement(1959535..1960023) 1 NC_014550.1 fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid. Chorismic acid is a important intermediate in the synthesis of aromatic compounds, such as aromatic amino acids (phenylalanine, tyrosine and tryptophan), p-aminobenzoic acid, folate and ubiquinone; shikimate kinase 1960023 aroK 9793683 aroK Arthrobacter arilaitensis Re117 shikimate kinase YP_003916910.1 1959535 R 861360 CDS YP_003916911.1 308177505 9793688 complement(1960037..1961236) 1 NC_014550.1 last enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid. Chorismic acid is a important intermediate in the synthesis of aromatic compounds, such as aromatic amino acids (phenylalanine, tyrosine and tryptophan), p-aminobenzoic acid, folate and ubiquinone; chorismate synthase 1961236 aroC 9793688 aroC Arthrobacter arilaitensis Re117 chorismate synthase YP_003916911.1 1960037 R 861360 CDS YP_003916912.1 308177506 9793684 complement(1961266..1962105) 1 NC_014550.1 fourth enzyme in the shikimate pathway, a seven- step biosynthetic pathway which converts erythrose-4- phosphate to chorismic acid. Chorismic acid is a important intermediate in the synthesis of aromatic compounds, such as aromatic amino acids (phenylalanine, tyrosine and tryptophan), p-aminobenzoic acid, folate and ubiquinone; shikimate dehydrogenase 1962105 aroE 9793684 aroE Arthrobacter arilaitensis Re117 shikimate dehydrogenase YP_003916912.1 1961266 R 861360 CDS YP_003916913.1 308177507 9793685 complement(1962177..1963622) 1 NC_014550.1 aminodeoxychorismate lyase converts 4- aminodeoxychorismate to pyruvate and p-aminobenzoate, a precursor of folic acid in bacteria. Identified by match to protein family PF02618; aminodeoxychorismate lyase 1963622 9793685 AARI_17280 Arthrobacter arilaitensis Re117 aminodeoxychorismate lyase YP_003916913.1 1962177 R 861360 CDS YP_003916914.1 308177508 9795802 complement(1963668..1964141) 1 NC_014550.1 identified by match to protein family TIGR00250. Could be a nuclease that resolves Holliday junction intermediates in genetic recombination; Holliday junction resolvase 1964141 9795802 AARI_17290 Arthrobacter arilaitensis Re117 Holliday junction resolvase YP_003916914.1 1963668 R 861360 CDS YP_003916915.1 308177509 9795803 complement(1964134..1966824) 1 NC_014550.1 alanine-tRNA ligase 1966824 alaS 9795803 alaS Arthrobacter arilaitensis Re117 alanine-tRNA ligase YP_003916915.1 1964134 R 861360 CDS YP_003916916.1 308177510 9793660 complement(1966844..1967053) 1 NC_014550.1 hypothetical protein 1967053 9793660 AARI_17310 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916916.1 1966844 R 861360 CDS YP_003916917.1 308177511 9795804 complement(1967134..1967505) 1 NC_014550.1 signal peptide predicted by SignalP 3.0 HMM (probability: 0.558) with cleavage site probability 0.558 between position 23 and 24; hypothetical protein 1967505 9795804 AARI_17320 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916917.1 1967134 R 861360 CDS YP_003916918.1 308177512 9795805 complement(1967632..1968255) 1 NC_014550.1 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit; 30S ribosomal protein S20 1968255 rpsD 9795805 rpsD Arthrobacter arilaitensis Re117 30S ribosomal protein S20 YP_003916918.1 1967632 R 861360 CDS YP_003916919.1 308177513 9794351 complement(1968442..1969848) 1 NC_014550.1 replication-associated recombination protein A 1969848 rarA 9794351 rarA Arthrobacter arilaitensis Re117 replication-associated recombination protein A YP_003916919.1 1968442 R 861360 CDS YP_003916920.1 308177514 9794281 1969938..1970375 1 NC_014550.1 cell growth inhibition by several D-amino acids can be explained by an in vivo production of D-aminoacyl-tRNA molecules. D-tyrosyl-tRNA(Tyr) deacylase cleaves any D- amino acid (and glycine, which does not have distinct D/L forms) from charged tRNA; D-tyrosyl-tRNA(Tyr) deacylase 1970375 dtd 9794281 dtd Arthrobacter arilaitensis Re117 D-tyrosyl-tRNA(Tyr) deacylase YP_003916920.1 1969938 D 861360 CDS YP_003916921.1 308177515 9793829 complement(1970372..1970701) 1 NC_014550.1 identified by match to protein family PF03551; PadR-like family transcriptional regulator 1970701 9793829 AARI_17360 Arthrobacter arilaitensis Re117 PadR-like family transcriptional regulator YP_003916921.1 1970372 R 861360 CDS YP_003916922.1 308177516 9795806 complement(1970694..1971812) 1 NC_014550.1 6 transmembrane helices predicted by TMHMM2.0; hypothetical protein 1971812 9795806 AARI_17370 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916922.1 1970694 R 861360 CDS YP_003916923.1 308177517 9795807 complement(1971908..1973185) 1 NC_014550.1 transposase of ISAar15, ISL3 family 1973185 9795807 AARI_35240 Arthrobacter arilaitensis Re117 transposase of ISAar15, ISL3 family YP_003916923.1 1971908 R 861360 CDS YP_003916924.1 308177518 9793466 complement(1973387..1975174) 1 NC_014550.1 activates aspartate and transfers it to tRNA(Asp) as the first step in protein biosynthesis; aspartate--tRNA ligase 1975174 aspS 9793466 aspS Arthrobacter arilaitensis Re117 aspartate--tRNA ligase YP_003916924.1 1973387 R 861360 CDS YP_003916925.1 308177519 9793698 complement(1975264..1976586) 1 NC_014550.1 activates histidine and transfers it to tRNA(His) as the first step in protein biosynthesis; histidine--tRNA ligase 1976586 hisS 9793698 hisS Arthrobacter arilaitensis Re117 histidine--tRNA ligase YP_003916925.1 1975264 R 861360 CDS YP_003916926.1 308177520 9793969 1976730..1978088 1 NC_014550.1 hypothetical protein 1978088 9793969 AARI_17400 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916926.1 1976730 D 861360 CDS YP_003916927.1 308177521 9795808 1978149..1978772 1 NC_014550.1 hypothetical protein 1978772 9795808 AARI_17410 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916927.1 1978149 D 861360 CDS YP_003916928.1 308177522 9795809 complement(1978801..1981068) 1 NC_014550.1 GTP diphosphokinase (EC 2.7.6.5) produces pppGpp (or ppGpp) from ATP and GTP (or GDP). Guanosine-3,5- bis(diphosphate) 3-diphosphatase (EC 3.1.7.2) hydrolyzes ppGpp into GTP. In eubacteria ppGpp is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance; bifunctional GTP diphosphokinase/guanosine-3',5'-bis(diphosphate) 3'-diphosphatase 1981068 9795809 AARI_17420 Arthrobacter arilaitensis Re117 bifunctional GTP diphosphokinase/guanosine-3',5'-bis(diphosphate) 3'-diphosphatase YP_003916928.1 1978801 R 861360 CDS YP_003916929.1 308177523 9795810 complement(1981309..1982277) 1 NC_014550.1 identified by match to protein family PF02355. The translocase itself comprises 7 proteins, including a chaperone protein (SecB), an ATPase (SecA), an integral membrane complex (SecCY, SecE and SecG), and two additional membrane proteins that promote the release of the mature peptide into the periplasm (SecD and SecF); protein-export membrane protein SecF 1982277 secF 9795810 secF Arthrobacter arilaitensis Re117 protein-export membrane protein SecF YP_003916929.1 1981309 R 861360 CDS YP_003916930.1 308177524 9794389 complement(1982270..1984012) 1 NC_014550.1 signal peptide predicted by SignalP 3.0 HMM (probability: 1.000) with cleavage site probability 0.509 between position 32 and 33. The translocase itself comprises 7 proteins, including a chaperone protein (SecB), an ATPase (SecA), an integral membrane complex (SecCY, SecE and SecG), and two additional membrane proteins that promote the release of the mature peptide into the periplasm (SecD and SecF); protein-export membrane protein SecD 1984012 secD 9794389 secD Arthrobacter arilaitensis Re117 protein-export membrane protein SecD YP_003916930.1 1982270 R 861360 CDS YP_003916931.1 308177525 9794387 complement(1984073..1984483) 1 NC_014550.1 match to bacterial YajC preprotein translocase signature PR02699. The translocase itself comprises 7 proteins, including a chaperone protein (SecB), an ATPase (SecA), an integral membrane complex (SecCY, SecE and SecG), and two additional membrane proteins that promote the release of the mature peptide into the periplasm (SecD and SecF). Other cytoplasmic/periplasmic proteins play a part in preprotein translocase activity, namely YidC and YajC. The latter is bound in a complex to SecD and SecF, and plays a part in stabilising and regulating secretion through the SecYEG integral membrane component via SecA; preprotein translocase subunit YajC 1984483 yajC 9794387 yajC Arthrobacter arilaitensis Re117 preprotein translocase subunit YajC YP_003916931.1 1984073 R 861360 CDS YP_003916932.1 308177526 9794516 complement(1984671..1985720) 1 NC_014550.1 the RuvB protein makes up part of the RuvABC revolvasome which catalyses the resolution of Holliday junctions that arise during genetic recombination and DNA repair; Holliday junction ATP-dependent DNA helicase RuvB 1985720 ruvB 9794516 ruvB Arthrobacter arilaitensis Re117 Holliday junction ATP-dependent DNA helicase RuvB YP_003916932.1 1984671 R 861360 CDS YP_003916933.1 308177527 9794372 complement(1985748..1986365) 1 NC_014550.1 the RuvA protein makes up part of the RuvABC revolvasome which catalyses the resolution of Holliday junctions that arise during genetic recombination and DNA repair; Holliday junction ATP-dependent DNA helicase RuvA 1986365 ruvA 9794372 ruvA Arthrobacter arilaitensis Re117 Holliday junction ATP-dependent DNA helicase RuvA YP_003916933.1 1985748 R 861360 CDS YP_003916934.1 308177528 9794371 complement(1986473..1987072) 1 NC_014550.1 the RuvC protein makes up part of the RuvABC revolvasome which catalyses the resolution of Holliday junctions that arise during genetic recombination and DNA repair; crossover junction endodeoxyribonuclease RuvC 1987072 ruvC 9794371 ruvC Arthrobacter arilaitensis Re117 crossover junction endodeoxyribonuclease RuvC YP_003916934.1 1986473 R 861360 CDS YP_003916935.1 308177529 9794373 complement(1987076..1987834) 1 NC_014550.1 hypothetical protein 1987834 9794373 AARI_17490 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916935.1 1987076 R 861360 CDS YP_003916936.1 308177530 9795811 complement(1987838..1988449) 1 NC_014550.1 involved in pyridoxal biosynthesis. Hydrolyses glutamine to glutamate and ammonia. Channels an ammonia molecule to pdxS; glutamine amidotransferase subunit PdxT 1988449 pdxT 9795811 pdxT Arthrobacter arilaitensis Re117 glutamine amidotransferase subunit PdxT YP_003916936.1 1987838 R 861360 CDS YP_003916937.1 308177531 9794191 1988607..1989440 1 NC_014550.1 catalyzes the reduction of 2,5-diketogluconic acid to 2-keto-L-gulonic acid, a key intermediate in the production of ascorbic acid. Can also reduce ethyl 2- methylacetoacetate stereoselectively to ethyl (2R)-methyl- (3S)-hydroxybutanoate and can also accept some other beta- keto esters. Identified by similarity to protein SP:Q46857 (Escherichia coli); 2,5-didehydrogluconate reductase 1989440 dkgA 9794191 dkgA Arthrobacter arilaitensis Re117 2,5-didehydrogluconate reductase YP_003916937.1 1988607 D 861360 CDS YP_003916938.1 308177532 9793818 1989486..1989611 1 NC_014550.1 hypothetical protein 1989611 9793818 AARI_17520 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916938.1 1989486 D 861360 CDS YP_003916939.1 308177533 9795812 1989633..1990121 1 NC_014550.1 hypothetical protein 1990121 9795812 AARI_17530 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916939.1 1989633 D 861360 CDS YP_003916940.1 308177534 9795813 complement(1990123..1991325) 1 NC_014550.1 identified by match to PF09587. Poly-gamma- glutamate is a natural polymer that may be involved in virulence and may help bacteria survive in high salt concentrations. It is a surface-associated protein; poly-gamma-glutamate capsule biosynthesis protein 1991325 9795813 AARI_17540 Arthrobacter arilaitensis Re117 poly-gamma-glutamate capsule biosynthesis protein YP_003916940.1 1990123 R 861360 CDS YP_003916941.1 308177535 9795814 1991402..1993414 1 NC_014550.1 hydrolyzes unblocked, C-terminal dipeptides from oligopeptides, with broad specificity; peptidyl-dipeptidase 1993414 dcp 9795814 dcp Arthrobacter arilaitensis Re117 peptidyl-dipeptidase YP_003916941.1 1991402 D 861360 CDS YP_003916942.1 308177536 9793795 1993414..1994181 1 NC_014550.1 identified by match to PF00583: acetyltransferase (GNAT) family; GNAT family acetyltransferase 1994181 9793795 AARI_17560 Arthrobacter arilaitensis Re117 GNAT family acetyltransferase YP_003916942.1 1993414 D 861360 CDS YP_003916943.1 308177537 9794519 complement(1994256..1994816) 1 NC_014550.1 match to protein domain PF01872. This domain is found in the C-terminus of the bifunctional deaminase- reductase in combination with PF00383 as well as in isolation in some archaebacterial proteins; RibD domain-containing protein 1994816 9794519 AARI_17570 Arthrobacter arilaitensis Re117 RibD domain-containing protein YP_003916943.1 1994256 R 861360 CDS YP_003916944.1 308177538 9794521 complement(1995874..1996026) 1 NC_014550.1 hypothetical protein 1996026 9794521 AARI_17590 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916944.1 1995874 R 861360 CDS YP_003916945.1 308177539 9794522 complement(1996494..1997396) 1 NC_014550.1 combines ammonia with five- and three-carbon phosphosugars to form PLP (pyridoxal 5-phosphate) which is the biologically active form of vitamin B6. Forms a complex with pdxT; pyridoxal biosynthesis lyase PdxS 1997396 pdxS 9794522 pdxS Arthrobacter arilaitensis Re117 pyridoxal biosynthesis lyase PdxS YP_003916945.1 1996494 R 861360 CDS YP_003916946.1 308177540 9794190 complement(1997976..1998542) 1 NC_014550.1 match to PF01230: histidine triad motif. The histidine triad motif (HIT) is related to the sequence H- phi-H-phi-H-phi-phi (where phi is a hydrophobic amino acid). Proteins containing HIT domains form a superfamily of nucleotide hydrolases and transferases that act on the alpha-phosphate of ribonucleotides; histidine triad family protein 1998542 9794190 AARI_17610 Arthrobacter arilaitensis Re117 histidine triad family protein YP_003916946.1 1997976 R 861360 CDS YP_003916947.1 308177541 9794523 complement(1998566..2000581) 1 NC_014550.1 activates threonine and transfers it to tRNA(Thr) as the first step in protein biosynthesis; threonine--tRNA ligase 2000581 thrS 9794523 thrS Arthrobacter arilaitensis Re117 threonine--tRNA ligase YP_003916947.1 1998566 R 861360 CDS YP_003916948.1 308177542 9794451 complement(2000690..2000824) 1 NC_014550.1 hypothetical protein 2000824 9794451 AARI_17630 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916948.1 2000690 R 861360 CDS YP_003916949.1 308177543 9794524 2001120..2001707 1 NC_014550.1 hypothetical protein 2001707 9794524 AARI_17640 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916949.1 2001120 D 861360 CDS YP_003916950.1 308177544 9794525 complement(2001963..2002070) 1 NC_014550.1 hypothetical protein 2002070 9794525 AARI_17650 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916950.1 2001963 R 861360 CDS YP_003916951.1 308177545 9794526 2002207..2002647 1 NC_014550.1 identified by match to PF00903: glyoxalase/bleomycin resistance protein/dioxygenase superfamily; glyoxalase family protein 2002647 9794526 AARI_17660 Arthrobacter arilaitensis Re117 glyoxalase family protein YP_003916951.1 2002207 D 861360 CDS YP_003916952.1 308177546 9794527 complement(2002648..2006103) 1 NC_014550.1 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The beta chain is required for initiation of replication once it is clamped onto DNA. DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII complex. PolIII associates with the gamma complex (composed of gamma, delta, delta prime, psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex; DNA polymerase III subunit alpha 2006103 dnaE 9794527 dnaE Arthrobacter arilaitensis Re117 DNA polymerase III subunit alpha YP_003916952.1 2002648 R 861360 CDS YP_003916953.1 308177547 9793822 complement(2006141..2006455) 1 NC_014550.1 hypothetical protein 2006455 9793822 AARI_17680 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916953.1 2006141 R 861360 CDS YP_003916954.1 308177548 9794528 2006541..2006762 1 NC_014550.1 hypothetical protein 2006762 9794528 AARI_17690 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916954.1 2006541 D 861360 CDS YP_003916955.1 308177549 9794529 2006927..2008012 1 NC_014550.1 catalyses the following reaction: formaldehyde + mycothiol + NAD+ = S-formylmycothiol + NADH + H+. The S- formylmycothiol formed hydrolyses to mycothiol and formate; mycothiol-dependent formaldehyde dehydrogenase 2008012 9794529 AARI_17700 Arthrobacter arilaitensis Re117 mycothiol-dependent formaldehyde dehydrogenase YP_003916955.1 2006927 D 861360 CDS YP_003916956.1 308177550 9794530 2008012..2008641 1 NC_014550.1 identified by match to PF00753: metallo-beta- lactamase superfamily. Apart from the beta-lactamases, a number of other proteins contain this domain. These proteins include thiolesterases, members of the glyoxalase II family, that catalyse the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid and a competence protein that is essential for natural transformation in Neisseria gonorrhoeae and could be a transporter involved in DNA uptake; metallo-beta-lactamase 2008641 9794530 AARI_17710 Arthrobacter arilaitensis Re117 metallo-beta-lactamase YP_003916956.1 2008012 D 861360 CDS YP_003916957.1 308177551 9794531 2008738..2009250 1 NC_014550.1 4 transmembrane helices predicted by TMHMM2.0; hypothetical protein 2009250 9794531 AARI_17720 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916957.1 2008738 D 861360 CDS YP_003916958.1 308177552 9794532 complement(2009247..2009975) 1 NC_014550.1 hypothetical protein 2009975 9794532 AARI_17730 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916958.1 2009247 R 861360 CDS YP_003916959.1 308177553 9794533 2010102..2010380 1 NC_014550.1 identified by match to protein family PF00462; glutaredoxin-like protein 2010380 9794533 AARI_17740 Arthrobacter arilaitensis Re117 glutaredoxin-like protein YP_003916959.1 2010102 D 861360 CDS YP_003916960.1 308177554 9794534 complement(2010436..2011140) 1 NC_014550.1 hypothetical protein 2011140 9794534 AARI_17750 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916960.1 2010436 R 861360 CDS YP_003916961.1 308177555 9794535 2011269..2011883 1 NC_014550.1 uridine kinase catalyzes the phosphoryl transfer from ATP to uridine or cytidine to yield UMP or CMP. In the primidine nucleotide-salvage pathway, this enzyme combined with nucleoside diphosphate kinases further phosphorylates UMP and CMP to form UTP and CTP; uridine kinase-like protein 2011883 9794535 AARI_17760 Arthrobacter arilaitensis Re117 uridine kinase-like protein YP_003916961.1 2011269 D 861360 CDS YP_003916962.1 308177556 9794536 complement(2011880..2012698) 1 NC_014550.1 hypothetical protein 2012698 9794536 AARI_17770 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916962.1 2011880 R 861360 CDS YP_003916963.1 308177557 9794537 complement(2012772..2013347) 1 NC_014550.1 match to PF01381: helix-turn-helix. This is large family of DNA binding helix-turn helix proteins that include a bacterial plasmid copy control protein, bacterial methylases, various bacteriophage transcription control proteins and a vegetative specific protein from Dictyostelium discoideum (Slime mould); hypothetical protein 2013347 9794537 AARI_17780 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916963.1 2012772 R 861360 CDS YP_003916964.1 308177558 9794538 2013422..2014339 1 NC_014550.1 match to PF07992: pyridine nucleotide-disulphide oxidoreductase. This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases; oxidoreductase 2014339 9794538 AARI_17790 Arthrobacter arilaitensis Re117 oxidoreductase YP_003916964.1 2013422 D 861360 CDS YP_003916965.1 308177559 9794539 2015035..2015238 1 NC_014550.1 match to PF00313: cold-shock DNA-binding domain. The so-called cold shock proteins are thought to help the cell to survive in temperatures lower than optimum growth temperature, by contrast with heat shock proteins, which help the cell to survive in temperatures greater than the optimum, possibly by condensation of the chromosome and organization of the prokaryotic nucleoid; cold shock protein 2015238 9794539 AARI_17800 Arthrobacter arilaitensis Re117 cold shock protein YP_003916965.1 2015035 D 861360 CDS YP_003916966.1 308177560 9793467 2016529..2018085 1 NC_014550.1 transposase of ISAar36, IS21 family, istA 2018085 istA 9793467 istA Arthrobacter arilaitensis Re117 transposase of ISAar36, IS21 family, istA YP_003916966.1 2016529 D 861360 CDS YP_003916967.1 308177561 9793468 2018406..2018702 1 NC_014550.1 transposase of ISAar4, IS3 family, IS3 group, orfA 2018702 9793468 AARI_35280 Arthrobacter arilaitensis Re117 transposase of ISAar4, IS3 family, IS3 group, orfA YP_003916967.1 2018406 D 861360 CDS YP_003916968.1 308177562 9793469 2018765..2019592 1 NC_014550.1 transposase of ISAar4, IS3 family, IS3 group, orfB 2019592 9793469 AARI_35290 Arthrobacter arilaitensis Re117 transposase of ISAar4, IS3 family, IS3 group, orfB YP_003916968.1 2018765 D 861360 CDS YP_003916969.1 308177563 9793472 complement(2021220..2022491) 1 NC_014550.1 major facilitator superfamily (TC 2.A.1.y.z). Identified by match to protein family PF07690 (Major Facilitator Superfamily); MFS superfamily transporter 2022491 9793472 AARI_17810 Arthrobacter arilaitensis Re117 MFS superfamily transporter YP_003916969.1 2021220 R 861360 CDS YP_003916970.1 308177564 9794541 complement(2023496..2024470) 1 NC_014550.1 ribonucleotide reductase catalyzes the reductive synthesis of deoxyribonucleotides from their corresponding ribonucleotides. It provides the precursors necessary for DNA synthesis. It is an oligomeric enzyme composed of a large subunit (700 to 1000 residues) and a small subunit (300 to 400 residues); ribonucleoside-diphosphate reductase subunit beta 2024470 nrdF 9794541 nrdF Arthrobacter arilaitensis Re117 ribonucleoside-diphosphate reductase subunit beta YP_003916970.1 2023496 R 861360 CDS YP_003916971.1 308177565 9794146 complement(2024685..2026823) 1 NC_014550.1 catalyzes the reductive synthesis of deoxyribonucleotides from their corresponding ribonucleotides. It provides the precursors necessary for DNA synthesis. It is an oligomeric enzyme composed of a large subunit (700 to 1000 residues) and a small subunit (300 to 400 residues); ribonucleoside-diphosphate reductase subunit alpha 2026823 nrdE 9794146 nrdE Arthrobacter arilaitensis Re117 ribonucleoside-diphosphate reductase subunit alpha YP_003916971.1 2024685 R 861360 CDS YP_003916972.1 308177566 9794144 complement(2026820..2027305) 1 NC_014550.1 probably involved in ribonucleotide reductase function. ribonucleotide reductases are enzymes that provide the precursors of DNA synthesis; NrdI protein 2027305 nrdI 9794144 nrdI Arthrobacter arilaitensis Re117 NrdI protein YP_003916972.1 2026820 R 861360 CDS YP_003916973.1 308177567 9794150 complement(2027347..2027577) 1 NC_014550.1 electron transport system for the ribonucleotide reductase system nrdEF; glutaredoxin electron transport component NrdH 2027577 nrdH 9794150 nrdH Arthrobacter arilaitensis Re117 glutaredoxin electron transport component NrdH YP_003916973.1 2027347 R 861360 CDS YP_003916974.1 308177568 9794148 complement(2028091..2028828) 1 NC_014550.1 pyridoxal phosphate-dependent enzyme 2028828 9794148 AARI_17860 Arthrobacter arilaitensis Re117 pyridoxal phosphate-dependent enzyme YP_003916974.1 2028091 R 861360 CDS YP_003916975.1 308177569 9794542 complement(2028904..2030628) 1 NC_014550.1 TPP-binding module. Catalyzes the formation of acetate from pyruvate (catalytic activity: pyruvate + ferricytochrome b1 + H2O = acetate + CO2 + ferrocytochrome b1); pyruvate dehydrogenase (cytochrome) 2030628 poxB 9794542 poxB Arthrobacter arilaitensis Re117 pyruvate dehydrogenase (cytochrome) YP_003916975.1 2028904 R 861360 CDS YP_003916976.1 308177570 9794214 complement(2030791..2031552) 1 NC_014550.1 pyridoxal phosphate-dependent enzyme 2031552 9794214 AARI_17880 Arthrobacter arilaitensis Re117 pyridoxal phosphate-dependent enzyme YP_003916976.1 2030791 R 861360 CDS YP_003916977.1 308177571 9794543 2031642..2032001 1 NC_014550.1 hypothetical protein 2032001 9794543 AARI_17890 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916977.1 2031642 D 861360 CDS YP_003916978.1 308177572 9794544 complement(2031998..2033059) 1 NC_014550.1 identified by match to PF00291: pyridoxal-phosphate dependent enzyme; pyridoxal phosphate-dependent enzyme 2033059 9794544 AARI_17900 Arthrobacter arilaitensis Re117 pyridoxal phosphate-dependent enzyme YP_003916978.1 2031998 R 861360 CDS YP_003916979.1 308177573 9794545 2033120..2033926 1 NC_014550.1 signal peptide predicted by SignalP 3.0 HMM (probability: 0.987) with cleavage site probability 0.704 between position 24 and 25. 7 transmembrane helices predicted by TMHMM2.0; hypothetical protein 2033926 9794545 AARI_17910 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916979.1 2033120 D 861360 CDS YP_003916980.1 308177574 9794546 2034026..2034373 1 NC_014550.1 1 transmembrane helice predicted by TMHMM2.0; hypothetical protein 2034373 9794546 AARI_17920 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916980.1 2034026 D 861360 CDS YP_003916981.1 308177575 9794547 complement(2034438..2036954) 1 NC_014550.1 signal peptide predicted by SignalP 3.0 HMM (probability: 1.000) with cleavage site probability 0.976 between position 27 and 28. 1 transmembrane helice predicted by TMHMM2.0; hypothetical protein 2036954 9794547 AARI_17930 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916981.1 2034438 R 861360 CDS YP_003916982.1 308177576 9794548 complement(2037049..2037423) 1 NC_014550.1 hypothetical protein 2037423 9794548 AARI_17940 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916982.1 2037049 R 861360 CDS YP_003916983.1 308177577 9794549 2037454..2039136 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, () drug resistance ATPase-2 (Drug RA2) family (TC 3.A.1.121.z). ABCISSE: fused ATP-binding protein (ABC2), ART-family, ARE-subfamily (antibiotic resistance); drug resistance ATP-binding protein 2039136 9794549 AARI_17950 Arthrobacter arilaitensis Re117 drug resistance ATP-binding protein YP_003916983.1 2037454 D 861360 CDS YP_003916984.1 308177578 9794551 complement(2039852..2041576) 1 NC_014550.1 the succinate dehydrogenase complex catalyses the interconversion of fumarate and succinate. It contains several subunits: a flavoprotein (SdhA), an iron-sulfur protein (SdhB), and membrane anchor proteins (SdhC and SdhD). Involved in the TCA cycle; succinate dehydrogenase flavoprotein subunit 2041576 sdhA 9794551 sdhA Arthrobacter arilaitensis Re117 succinate dehydrogenase flavoprotein subunit YP_003916984.1 2039852 R 861360 CDS YP_003916985.1 308177579 9794382 2041770..2042576 1 NC_014550.1 lysR family transcriptional regulator 2042576 9794382 AARI_17980 Arthrobacter arilaitensis Re117 lysR family transcriptional regulator YP_003916985.1 2041770 D 861360 CDS YP_003916986.1 308177580 9794552 2042665..2042904 1 NC_014550.1 hypothetical protein 2042904 9794552 AARI_17990 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916986.1 2042665 D 861360 CDS YP_003916987.1 308177581 9794553 2042917..2043195 1 NC_014550.1 hypothetical protein 2043195 9794553 AARI_18000 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916987.1 2042917 D 861360 CDS YP_003916988.1 308177582 9794554 complement(2043192..2044181) 1 NC_014550.1 identified by match to protein family PF01370: NAD dependent epimerase/dehydratase family. This family of proteins utilise NAD as a cofactor. The proteins in this family use nucleotide-sugar substrates for a variety of chemical reactions; NAD dependent epimerase/dehydratase family protein 2044181 9794554 AARI_18010 Arthrobacter arilaitensis Re117 NAD dependent epimerase/dehydratase family protein YP_003916988.1 2043192 R 861360 CDS YP_003916989.1 308177583 9794555 complement(2044192..2045067) 1 NC_014550.1 hypothetical protein 2045067 9794555 AARI_18020 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916989.1 2044192 R 861360 CDS YP_003916990.1 308177584 9794556 complement(2045131..2045988) 1 NC_014550.1 identified by match to PF00106. The short-chain dehydrogenases/reductases family (SDR) is a very large family of enzymes, most of which are known to be NAD- or NADP-dependent oxidoreductases; short-chain dehydrogenases/reductases family protein 2045988 9794556 AARI_18030 Arthrobacter arilaitensis Re117 short-chain dehydrogenases/reductases family protein YP_003916990.1 2045131 R 861360 CDS YP_003916991.1 308177585 9794557 2046133..2046645 1 NC_014550.1 identified by match to protein family PF01037; AsnC/Lrp family transcriptional regulator 2046645 9794557 AARI_18040 Arthrobacter arilaitensis Re117 AsnC/Lrp family transcriptional regulator YP_003916991.1 2046133 D 861360 CDS YP_003916992.1 308177586 9794558 2046851..2047909 1 NC_014550.1 may catalyze the transamination reaction in phenylalanine biosynthesis; phenylalanine aminotransferase 2047909 pat 9794558 pat Arthrobacter arilaitensis Re117 phenylalanine aminotransferase YP_003916992.1 2046851 D 861360 CDS YP_003916993.1 308177587 9794178 2047906..2049282 1 NC_014550.1 amino acid-polyamine-organocation (APC) superfamily, amino acid transporter (AAT) family (TC 2.A.3.1.z); amino acid transporter 2049282 9794178 AARI_18060 Arthrobacter arilaitensis Re117 amino acid transporter YP_003916993.1 2047906 D 861360 CDS YP_003916994.1 308177588 9794559 complement(2049319..2049993) 1 NC_014550.1 hypothetical protein 2049993 9794559 AARI_18070 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916994.1 2049319 R 861360 CDS YP_003916995.1 308177589 9794560 complement(2050005..2050622) 1 NC_014550.1 hypothetical protein 2050622 9794560 AARI_18080 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916995.1 2050005 R 861360 CDS YP_003916996.1 308177590 9794561 complement(2050646..2051737) 1 NC_014550.1 CorA metal ion transporter (MIT) family protein (TC 1.A.35.y.z). Functionally characterized proteins from this family includes the Mg2+-Co2+-Ni2+ CorA permeases of Salmonella typhimurium and E. coli. Match to protein family PF01544; metal ion transporter 2051737 9794561 AARI_18090 Arthrobacter arilaitensis Re117 metal ion transporter YP_003916996.1 2050646 R 861360 CDS YP_003916997.1 308177591 9794562 complement(2051820..2053550) 1 NC_014550.1 identified by match to cd00085: HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins; HNH endonuclease domain-containing protein 2053550 9794562 AARI_18100 Arthrobacter arilaitensis Re117 HNH endonuclease domain-containing protein YP_003916997.1 2051820 R 861360 CDS YP_003916998.1 308177592 9793621 complement(2053805..2054185) 1 NC_014550.1 identified by match to protein family TIGR00090: iojap homolog; Iojap-like protein 2054185 9793621 AARI_18110 Arthrobacter arilaitensis Re117 Iojap-like protein YP_003916998.1 2053805 R 861360 CDS YP_003916999.1 308177593 9794564 complement(2054243..2055730) 1 NC_014550.1 1 transmembrane helice predicted by TMHMM2.0; hypothetical protein 2055730 9794564 AARI_18120 Arthrobacter arilaitensis Re117 hypothetical protein YP_003916999.1 2054243 R 861360 CDS YP_003917000.1 308177594 9794565 complement(2055813..2056418) 1 NC_014550.1 catalyses the following reaction: ATP + nicotinate ribonucleotide <=> diphosphate + deamido-NAD(+). Involved in the biosynthesis of NAD(+) and NADP(+); nicotinate-nucleotide adenylyltransferase 2056418 nadD 9794565 nadD Arthrobacter arilaitensis Re117 nicotinate-nucleotide adenylyltransferase YP_003917000.1 2055813 R 861360 CDS YP_003917001.1 308177595 9794129 complement(2056421..2056633) 1 NC_014550.1 1 transmembrane helice predicted by TMHMM2.0; hypothetical protein 2056633 9794129 AARI_18140 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917001.1 2056421 R 861360 CDS YP_003917002.1 308177596 9794566 complement(2056752..2058038) 1 NC_014550.1 catalyzes the NADP-dependent reduction of L- glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. Involved in proline biosynthesis from glutamate; glutamate-5-semialdehyde dehydrogenase 2058038 proA 9794566 proA Arthrobacter arilaitensis Re117 glutamate-5-semialdehyde dehydrogenase YP_003917002.1 2056752 R 861360 CDS YP_003917003.1 308177597 9794223 complement(2058055..2059212) 1 NC_014550.1 catalyzes the ATP-dependent phosphorylation of L- glutamate into L-glutamate 5-phosphate. Involved in proline biosynthesis from glutamate; glutamate 5-kinase 2059212 proB 9794223 proB Arthrobacter arilaitensis Re117 glutamate 5-kinase YP_003917003.1 2058055 R 861360 CDS YP_003917004.1 308177598 9794224 complement(2059216..2060805) 1 NC_014550.1 Obg proteins are among a large group of GTP binding proteins conserved from bacteria to humans. The E. coli homolog, ObgE is believed to function in ribosomal biogenesis; Obg family GTP-binding protein 2060805 9794224 AARI_18170 Arthrobacter arilaitensis Re117 Obg family GTP-binding protein YP_003917004.1 2059216 R 861360 CDS YP_003917005.1 308177599 9794567 complement(2060930..2061184) 1 NC_014550.1 L27 is a protein from the large (50S) subunit; 50S ribosomal protein L27 2061184 rpmA 9794567 rpmA Arthrobacter arilaitensis Re117 50S ribosomal protein L27 YP_003917005.1 2060930 R 861360 CDS YP_003917006.1 308177600 9794333 complement(2061233..2061541) 1 NC_014550.1 part of the 50S ribosomal subunit. Binds to 23S rRNA in the presence of protein L20; 50S ribosomal protein L21 2061541 rplU 9794333 rplU Arthrobacter arilaitensis Re117 50S ribosomal protein L21 YP_003917006.1 2061233 R 861360 CDS YP_003917007.1 308177601 9794328 complement(2061772..2064612) 1 NC_014550.1 match to PF10150: ribonuclease E/G family. Ribonuclease E and Ribonuclease G are related enzymes that cleave a wide variety of RNAs. In E. coli, both RNase E and RNase G have been shown to play a role in the maturation of the 5 end of 16S RNA; ribonuclease 2064612 9794328 AARI_18200 Arthrobacter arilaitensis Re117 ribonuclease YP_003917007.1 2061772 R 861360 CDS YP_003917008.1 308177602 9794568 2065220..2065843 1 NC_014550.1 5 transmembrane helices predicted by TMHMM2.0. Match to IPR012932: vitamin K epoxide reductase; hypothetical protein 2065843 9794568 AARI_18210 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917008.1 2065220 D 861360 CDS YP_003917009.1 308177603 9794569 2066112..2066696 1 NC_014550.1 identified by match to PF00583: acetyltransferase (GNAT) family; GNAT family acetyltransferase 2066696 9794569 AARI_18220 Arthrobacter arilaitensis Re117 GNAT family acetyltransferase YP_003917009.1 2066112 D 861360 CDS YP_003917010.1 308177604 9794570 2066920..2068209 1 NC_014550.1 8 transmembrane helices predicted by TMHMM2.0; hypothetical protein 2068209 9794570 AARI_18230 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917010.1 2066920 D 861360 CDS YP_003917011.1 308177605 9794571 2068562..2068768 1 NC_014550.1 hypothetical protein 2068768 9794571 AARI_18240 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917011.1 2068562 D 861360 CDS YP_003917012.1 308177606 9794572 complement(2068832..2069248) 1 NC_014550.1 catalyses the following reaction: ATP + nucleoside diphosphate <=> ADP + nucleoside triphosphate. Required for the synthesis of nucleoside triphosphates other than ATP; nucleoside-diphosphate kinase 2069248 ndk 9794572 ndk Arthrobacter arilaitensis Re117 nucleoside-diphosphate kinase YP_003917012.1 2068832 R 861360 CDS YP_003917013.1 308177607 9794137 complement(2069289..2069723) 1 NC_014550.1 signal peptide predicted by SignalP 3.0 HMM (probability: 0.872) with cleavage site probability 0.380 between position 52 and 53. 2 transmembrane helices predicted by TMHMM2.0 after the signal peptide; hypothetical protein 2069723 9794137 AARI_18260 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917013.1 2069289 R 861360 CDS YP_003917014.1 308177608 9794573 complement(2069723..2071075) 1 NC_014550.1 leds to conversion of folates to polyglutamate derivatives. It preferes 5,10-methylenetetrahydrofolate, rather than 10-formyltetrahydrofolate as folate substrate: ATP + tetrahydropteroyl-(gamma-Glu)(n) + L-glutamate <=> ADP + phosphate + tetrahydropteroyl-(gamma-Glu)(n+1); tetrahydrofolate synthase 2071075 folC 9794573 folC Arthrobacter arilaitensis Re117 tetrahydrofolate synthase YP_003917014.1 2069723 R 861360 CDS YP_003917015.1 308177609 9793858 complement(2071075..2074335) 1 NC_014550.1 isoleucine-tRNA ligase 2074335 ileS 9793858 ileS Arthrobacter arilaitensis Re117 isoleucine-tRNA ligase YP_003917015.1 2071075 R 861360 CDS YP_003917016.1 308177610 9794001 2074785..2075339 1 NC_014550.1 3 transmembrane helices predicted by TMHMM2.0; hypothetical protein 2075339 9794001 AARI_18290 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917016.1 2074785 D 861360 CDS YP_003917017.1 308177611 9794574 2075390..2076637 1 NC_014550.1 protein-histidine kinases are key elements in two- component signal transduction systems, which enable bacteria to sense, respond, and adapt to a wide range of environments, stressors, and growth conditions. 5 transmembrane helices predicted by TMHMM2.0; signal transduction histidine kinase 2076637 9794574 AARI_18300 Arthrobacter arilaitensis Re117 signal transduction histidine kinase YP_003917017.1 2075390 D 861360 CDS YP_003917018.1 308177612 9794575 2076634..2077251 1 NC_014550.1 response regulators are key elements in two- component signal transduction systems, which enable bacteria to sense, respond, and adapt to a wide range of environments, stressors, and growth conditions; two-component system response regulator 2077251 9794575 AARI_18310 Arthrobacter arilaitensis Re117 two-component system response regulator YP_003917018.1 2076634 D 861360 CDS YP_003917019.1 308177613 9794576 2077364..2079466 1 NC_014550.1 Resistance-Nodulation-Cell Division (RND) superfamily (TC 2.A.6.y.z). Match to PS50156: sterol- sensing domain. In bacteria, this domain is found in a number of drug resistance proteins; drug exporter of the RND superfamily 2079466 9794576 AARI_18320 Arthrobacter arilaitensis Re117 drug exporter of the RND superfamily YP_003917019.1 2077364 D 861360 CDS YP_003917020.1 308177614 9794577 2079471..2079902 1 NC_014550.1 4 transmembranes helice predicted by TMHMM2.0; hypothetical protein 2079902 9794577 AARI_18330 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917020.1 2079471 D 861360 CDS YP_003917021.1 308177615 9794578 2080080..2081318 1 NC_014550.1 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The beta chain is required for initiation of replication once it is clamped onto DNA. DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII complex. PolIII associates with the gamma complex (composed of gamma, delta, delta, psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex; DNA polymerase III subunit epsilon 2081318 9794578 AARI_18340 Arthrobacter arilaitensis Re117 DNA polymerase III subunit epsilon YP_003917021.1 2080080 D 861360 CDS YP_003917022.1 308177616 9794579 complement(2081407..2082861) 1 NC_014550.1 sulfite reductase catalyzes the reduction of sulfite to sulphide. Involved in the sulfate assimilation pathway; sulfite reductase (NADPH) 2082861 9794579 AARI_18350 Arthrobacter arilaitensis Re117 sulfite reductase (NADPH) YP_003917022.1 2081407 R 861360 CDS YP_003917023.1 308177617 9794580 complement(2082879..2083658) 1 NC_014550.1 catalyzes two sequential methylation reactions, the first forming precorrin-1 and the second leading to the formation of precorrin-2 (dihydrosirohydrochlorin): (1) S- adenosyl-L-methionine + uroporphyrinogen III <=> S- adenosyl-L-homocysteine + precorrin-1, (2) S-adenosyl-L- methionine + precorrin-1 <=> S-adenosyl-L-homocysteine + precorrin-2; uroporphyrinogen-III C-methyltransferase 2083658 cobA 9794580 cobA Arthrobacter arilaitensis Re117 uroporphyrinogen-III C-methyltransferase YP_003917023.1 2082879 R 861360 CDS YP_003917024.1 308177618 9793751 complement(2083651..2084508) 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, taurine uptake transporter (TauT) family (TC 3.A.1.17.z). ABCISSE: ABC transporter, permease (IM), OTCN-family (osmoprotectants, taurine, cyanate and nitrate), aliphatic sulfonates import. Part of an ABC transporter complex involved in aliphatic sulfonates import; aliphatic sulfonates ABC transporter inner membrane subunit 2084508 9793751 AARI_18370 Arthrobacter arilaitensis Re117 aliphatic sulfonates ABC transporter inner membrane subunit YP_003917024.1 2083651 R 861360 CDS YP_003917025.1 308177619 9794581 complement(2084480..2085223) 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, taurine uptake transporter (TauT) family (TC 3.A.1.17.z). ABCISSE: ABC transporter, ATP-binding protein (ABC), OTCN- family (osmoprotectants, taurine, cyanate and nitrate), aliphatic sulfonates import. Part of an ABC transporter complex involved in aliphatic sulfonates import; aliphatic sulfonates ABC transporter ATP-binding subunit 2085223 9794581 AARI_18380 Arthrobacter arilaitensis Re117 aliphatic sulfonates ABC transporter ATP-binding subunit YP_003917025.1 2084480 R 861360 CDS YP_003917026.1 308177620 9794582 complement(2085223..2086320) 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, taurine uptake transporter (TauT) family (TC 3.A.1.17.z). ABCISSE: ABC transporter, binding protein (BP), OTCN- family (osmoprotectants, taurine, cyanate and nitrate), aliphatic sulfonates import. Part of an ABC transporter complex involved in aliphatic sulfonates import; aliphatic sulfonates ABC transporter substrate-binding protein 2086320 9794582 AARI_18390 Arthrobacter arilaitensis Re117 aliphatic sulfonates ABC transporter substrate-binding protein YP_003917026.1 2085223 R 861360 CDS YP_003917027.1 308177621 9794583 complement(2086307..2087602) 1 NC_014550.1 catalyses the formation of diphosphate and adenylyl sulphate from ATP and sulphate. This enzyme participates in 3 metabolic pathways: purine metabolism, selenoamino acid metabolism, and sulfur metabolism; sulfate adenylyltransferase large subunit 2087602 cysN 9794583 cysN Arthrobacter arilaitensis Re117 sulfate adenylyltransferase large subunit YP_003917027.1 2086307 R 861360 CDS YP_003917028.1 308177622 9793782 complement(2087604..2088527) 1 NC_014550.1 catalyses the formation of diphosphate and adenylyl sulphate from ATP and sulphate. This enzyme participates in 3 metabolic pathways: purine metabolism, selenoamino acid metabolism, and sulfur metabolism; sulfate adenylyltransferase small subunit 2088527 cysD 9793782 cysD Arthrobacter arilaitensis Re117 sulfate adenylyltransferase small subunit YP_003917028.1 2087604 R 861360 CDS YP_003917029.1 308177623 9793777 complement(2088539..2089261) 1 NC_014550.1 identified by similarity to protein SP:P65668 (Mycobacterium tuberculosis). Involved in sulfate assimilation. Catalyzes the following reaction: adenylyl sulfate (APS) + reduced acceptor => AMP + sulfite + acceptor; adenylyl-sulfate reductase 2089261 cysH 9793777 cysH Arthrobacter arilaitensis Re117 adenylyl-sulfate reductase YP_003917029.1 2088539 R 861360 CDS YP_003917030.1 308177624 9793779 complement(2089258..2090958) 1 NC_014550.1 catalyzes the reduction of sulfite to sulphide. Involved in the sulfate assimilation pathway; sulfite reductase (ferredoxin) 2090958 sir 9793779 sir Arthrobacter arilaitensis Re117 sulfite reductase (ferredoxin) YP_003917030.1 2089258 R 861360 CDS YP_003917031.1 308177625 9794396 complement(2091026..2091766) 1 NC_014550.1 identified by match to protein family PF01903. The function of CbiX is uncertain, however it is found in cobalamin biosynthesis operons and so may have a related function. Some CbiX proteins contain a striking histidine- rich region at their C-terminus, which suggests that it might be involved in metal chelation; CbiX family protein 2091766 9794396 AARI_18440 Arthrobacter arilaitensis Re117 CbiX family protein YP_003917031.1 2091026 R 861360 CDS YP_003917032.1 308177626 9794584 complement(2091797..2092561) 1 NC_014550.1 identified by match to PF00106. The short-chain dehydrogenases/reductases family (SDR) is a very large family of enzymes, most of which are known to be NAD- or NADP-dependent oxidoreductases; short-chain dehydrogenases/reductases family protein 2092561 9794584 AARI_18450 Arthrobacter arilaitensis Re117 short-chain dehydrogenases/reductases family protein YP_003917032.1 2091797 R 861360 CDS YP_003917033.1 308177627 9794585 2092766..2095384 1 NC_014550.1 valine-tRNA ligase 2095384 valS 9794585 valS Arthrobacter arilaitensis Re117 valine-tRNA ligase YP_003917033.1 2092766 D 861360 CDS YP_003917034.1 308177628 9794500 complement(2095446..2095634) 1 NC_014550.1 hypothetical protein 2095634 9794500 AARI_18470 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917034.1 2095446 R 861360 CDS YP_003917035.1 308177629 9794586 complement(2095704..2096711) 1 NC_014550.1 signal peptide predicted by SignalP 3.0 HMM (probability: 1.000) with cleavage site probability 1.000 between position 39 and 40; hypothetical protein 2096711 9794586 AARI_18480 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917035.1 2095704 R 861360 CDS YP_003917036.1 308177630 9794587 complement(2096902..2097972) 1 NC_014550.1 transposase of ISAar1, IS1595 family, ISSod11 group 2097972 9794587 AARI_35320 Arthrobacter arilaitensis Re117 transposase of ISAar1, IS1595 family, ISSod11 group YP_003917036.1 2096902 R 861360 CDS YP_003917037.1 308177631 9793473 complement(2098401..2099708) 1 NC_014550.1 transposase of ISAar19, ISL3 family 2099708 9793473 AARI_35330 Arthrobacter arilaitensis Re117 transposase of ISAar19, ISL3 family YP_003917037.1 2098401 R 861360 CDS YP_003917038.1 308177632 9793474 complement(2100251..2100859) 1 NC_014550.1 hypothetical protein 2100859 9793474 AARI_18490 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917038.1 2100251 R 861360 CDS YP_003917039.1 308177633 9794588 complement(2100905..2102197) 1 NC_014550.1 ATP-dependent Clp protease ATP-binding subunit ClpX 2102197 clpX 9794588 clpX Arthrobacter arilaitensis Re117 ATP-dependent Clp protease ATP-binding subunit ClpX YP_003917039.1 2100905 R 861360 CDS YP_003917040.1 308177634 9793743 complement(2102365..2103024) 1 NC_014550.1 Clp displays ATP-dependent endopeptidase activity. It contains subunits of two types, ClpP, with peptidase activity, and ClpA or ClpX, with ATPase activity; ATP-dependent Clp protease proteolytic subunit ClpP 2103024 clpP 9793743 clpP Arthrobacter arilaitensis Re117 ATP-dependent Clp protease proteolytic subunit ClpP YP_003917040.1 2102365 R 861360 CDS YP_003917041.1 308177635 9793740 complement(2103072..2103692) 1 NC_014550.1 Clp displays ATP-dependent endopeptidase activity. It contains subunits of two types, ClpP, with peptidase activity, and ClpA or ClpX, with ATPase activity; ATP-dependent Clp protease proteolytic subunit ClpP 2103692 clpP 9793740 clpP Arthrobacter arilaitensis Re117 ATP-dependent Clp protease proteolytic subunit ClpP YP_003917041.1 2103072 R 861360 CDS YP_003917042.1 308177636 9793741 complement(2103916..2105247) 1 NC_014550.1 the trigger factor is found in several prokaryotes, and is involved in protein export. It is a ribosome- associated molecular chaperone and is the first chaperone to interact with nascent polypeptide. It acts as a chaperone by maintaining the newly synthesised protein in an open conformation. The central domain of trigger factor has peptidyl-prolyl cis/trans isomerase activity (EC 5.2.1. 8); trigger factor 2105247 tig 9793741 tig Arthrobacter arilaitensis Re117 trigger factor YP_003917042.1 2103916 R 861360 CDS YP_003917043.1 308177637 9793625 complement(2106880..2107848) 1 NC_014550.1 involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases; DNA glycosylase 2107848 9793625 AARI_18540 Arthrobacter arilaitensis Re117 DNA glycosylase YP_003917043.1 2106880 R 861360 CDS YP_003917044.1 308177638 9794589 complement(2107851..2108324) 1 NC_014550.1 catalyzes the interconversion of ribose 5-phosphate to ribulose 5-phosphate. Involved in the pentose phosphate pathway; ribose-5-phosphate isomerase 2108324 rpi 9794589 rpi Arthrobacter arilaitensis Re117 ribose-5-phosphate isomerase YP_003917044.1 2107851 R 861360 CDS YP_003917045.1 308177639 9794309 2108614..2111154 1 NC_014550.1 catalyzes the removal of single amino acids from the amino terminus of small peptides; membrane alanyl aminopeptidase 2111154 pepN 9794309 pepN Arthrobacter arilaitensis Re117 membrane alanyl aminopeptidase YP_003917045.1 2108614 D 861360 CDS YP_003917046.1 308177640 9794194 complement(2111312..2112667) 1 NC_014550.1 transposase of ISAar28, IS481 family 2112667 9794194 AARI_35340 Arthrobacter arilaitensis Re117 transposase of ISAar28, IS481 family YP_003917046.1 2111312 R 861360 CDS YP_003917047.1 308177641 9793475 2112856..2113332 1 NC_014550.1 identified by match to protein family PF02566: OsmC, OsmC-like protein. Osmotically inducible protein C (OsmC) is a stress-induced protein found in Escherichia coli. This family also contains an organic hydroperoxide detoxification protein that has a novel pattern of oxidative stress regulation; OsmC-like protein 2113332 9793475 AARI_18570 Arthrobacter arilaitensis Re117 OsmC-like protein YP_003917047.1 2112856 D 861360 CDS YP_003917048.1 308177642 9794590 2113345..2113863 1 NC_014550.1 identified by match to protein family PF01152: bacterial-like globin. Globins are heme-containing proteins involved in binding and/or transporting oxygen; bacterial globin-like protein 2113863 9794590 AARI_18580 Arthrobacter arilaitensis Re117 bacterial globin-like protein YP_003917048.1 2113345 D 861360 CDS YP_003917049.1 308177643 9794591 complement(2113920..2114579) 1 NC_014550.1 hypothetical protein 2114579 9794591 AARI_18590 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917049.1 2113920 R 861360 CDS YP_003917050.1 308177644 9794592 2114755..2115648 1 NC_014550.1 identified by similarity to protein SP:P0AGG2 (Escherichia coli). Can hydrolyze a broad range of acyl- CoA thioesters. Its physiological function is not known; acyl-CoA thioesterase II 2115648 tesB 9794592 tesB Arthrobacter arilaitensis Re117 acyl-CoA thioesterase II YP_003917050.1 2114755 D 861360 CDS YP_003917051.1 308177645 9794436 complement(2115682..2117421) 1 NC_014550.1 match to PF03473. The MOSC (MOCO sulfurase C- terminal) domain is a superfamily of beta-strand-rich domains identified in the molybdenum cofactor sulfurase and several other proteins from both prokaryotes and eukaryotes. The MOSC domain is predicted to be a sulfur- carrier domain that receives sulfur abstracted by the pyridoxal phosphate-dependent NifS-like enzymes, on its conserved cysteine, and delivers it for the formation of diverse sulfur-metal clusters; MOSC domain-containing protein 2117421 9794436 AARI_18610 Arthrobacter arilaitensis Re117 MOSC domain-containing protein YP_003917051.1 2115682 R 861360 CDS YP_003917052.1 308177646 9794593 complement(2117530..2118036) 1 NC_014550.1 identified by match to protein family TIGR01950. SoxR is a MerR-family homodimeric transcription factor with a 2Fe-2S cluster in each monomer. The motif CIGCGCxxxxxC is conserved. Oxidation of the iron-sulfur cluster activates SoxR. The physiological role in E. coli is response to oxidative stress. It is activated by superoxide, singlet oxygen, nitric oxide (NO), and hydrogen peroxide. In E. coli, SoxR increases expression of transcription factor SoxS; different downstream targets may exist in other species; redox-sensitive transcriptional regulator SoxR 2118036 9794593 AARI_18620 Arthrobacter arilaitensis Re117 redox-sensitive transcriptional regulator SoxR YP_003917052.1 2117530 R 861360 CDS YP_003917053.1 308177647 9794594 2118170..2118676 1 NC_014550.1 identified by match to PF01613; flavin reductase-like domain protein 2118676 9794594 AARI_18630 Arthrobacter arilaitensis Re117 flavin reductase-like domain protein YP_003917053.1 2118170 D 861360 CDS YP_003917054.1 308177648 9794595 complement(2118745..2120427) 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, () drug resistance ATPase-2 (Drug RA2) family (TC 3.A.1.121.z). ABCISSE: fused ATP-binding protein (ABC2), ART-family, ARE-subfamily (antibiotic resistance); drug resistance ATP-binding protein 2120427 9794595 AARI_18640 Arthrobacter arilaitensis Re117 drug resistance ATP-binding protein YP_003917054.1 2118745 R 861360 CDS YP_003917055.1 308177649 9794596 complement(2120541..2120990) 1 NC_014550.1 this protein is essential for replication of the chromosome. It is also involved in DNA recombination and repair; single-stranded DNA-binding protein 2120990 ssb 9794596 ssb Arthrobacter arilaitensis Re117 single-stranded DNA-binding protein YP_003917055.1 2120541 R 861360 CDS YP_003917056.1 308177650 9794404 complement(2121081..2121980) 1 NC_014550.1 hypothetical protein 2121980 9794404 AARI_18660 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917056.1 2121081 R 861360 CDS YP_003917057.1 308177651 9794597 2122145..2123581 1 NC_014550.1 transposase of ISAar8, IS1380 family 2123581 9794597 AARI_35350 Arthrobacter arilaitensis Re117 transposase of ISAar8, IS1380 family YP_003917057.1 2122145 D 861360 CDS YP_003917058.1 308177652 9793626 complement(2124030..2125712) 1 NC_014550.1 identified by match to PF00890. This family includes members that bind FAD such as the flavoprotein subunits from succinate and fumarate dehydrogenase, aspartate oxidase and the alpha subunit of adenylylsulphate reductase; FAD binding domain-containing protein 2125712 9793626 AARI_18670 Arthrobacter arilaitensis Re117 FAD binding domain-containing protein YP_003917058.1 2124030 R 861360 CDS YP_003917059.1 308177653 9794598 2126004..2127221 1 NC_014550.1 major facilitator superfamily (TC 2.A.1.y.z). Identified by match to protein family PF07690; MFS superfamily transporter 2127221 9794598 AARI_18680 Arthrobacter arilaitensis Re117 MFS superfamily transporter YP_003917059.1 2126004 D 861360 CDS YP_003917060.1 308177654 9794599 complement(2127218..2127664) 1 NC_014550.1 identified by match to protein family PF01037; AsnC/Lrp family transcriptional regulator 2127664 9794599 AARI_18690 Arthrobacter arilaitensis Re117 AsnC/Lrp family transcriptional regulator YP_003917060.1 2127218 R 861360 CDS YP_003917061.1 308177655 9794600 2127821..2128537 1 NC_014550.1 resistance to homoSer/Thr (RhtB) family protein (TC 2.A.76.y.z). The family includes homoserine, threonine and leucine efflux proteins. The transport reaction presumably catalyzed by members of the RhtB family is: amino acid (in) + nH+ (out) <--> amino acid (out) + nH+ (in); RHBT family amino acid transporter 2128537 9794600 AARI_18700 Arthrobacter arilaitensis Re117 RHBT family amino acid transporter YP_003917061.1 2127821 D 861360 CDS YP_003917062.1 308177656 9794601 2128685..2129374 1 NC_014550.1 TC 3.A.1.y.z. ABCISSE: ABC transporter, ATP-binding protein (ABC), CBY-family (Cobalt uptake, unknown), Y179- subfamily (CBU-like systems). The function of CBU-like systems is unknown; ABC transporter ATP-binding subunit 2129374 9794601 AARI_18710 Arthrobacter arilaitensis Re117 ABC transporter ATP-binding subunit YP_003917062.1 2128685 D 861360 CDS YP_003917063.1 308177657 9794602 2129371..2129976 1 NC_014550.1 TC 3.A.1.y.z. ABCISSE: ABC transporter, permease (IM), CBY-family (Cobalt uptake, unknown), Y179-subfamily (CBU-like systems). The function of CBU-like systems is unknown; ABC transporter inner membrane subunit 2129976 9794602 AARI_18720 Arthrobacter arilaitensis Re117 ABC transporter inner membrane subunit YP_003917063.1 2129371 D 861360 CDS YP_003917064.1 308177658 9794603 2130022..2130603 1 NC_014550.1 TC 3.A.1.y.z. ABCISSE: ABC transporter, permease (IM), CBY-family (Cobalt uptake, unknown), Y179-subfamily (CBU-like systems). The function of CBU-like systems is unknown; ABC transporter inner membrane subunit 2130603 9794603 AARI_18730 Arthrobacter arilaitensis Re117 ABC transporter inner membrane subunit YP_003917064.1 2130022 D 861360 CDS YP_003917065.1 308177659 9794604 2130608..2132047 1 NC_014550.1 match to protein family PF00501. This family of enzymes includes luciferase, long chain fatty acid Co-A ligase, acetyl-CoA synthetase and various other closely- related synthetases; fatty-acid--Co-A ligase 2132047 9794604 AARI_18740 Arthrobacter arilaitensis Re117 fatty-acid--Co-A ligase YP_003917065.1 2130608 D 861360 CDS YP_003917066.1 308177660 9794605 2132044..2133222 1 NC_014550.1 acetyl-CoA C-acyltransferase (also named 3-ketoacyl- CoA thiolase or thiolase I) has a broad chain-length specificity for its substrates and is involved in degradative pathways such as fatty acid beta-oxidation; acetyl-CoA C-acyltransferase 2133222 9794605 AARI_18750 Arthrobacter arilaitensis Re117 acetyl-CoA C-acyltransferase YP_003917066.1 2132044 D 861360 CDS YP_003917067.1 308177661 9794606 complement(2133371..2133715) 1 NC_014550.1 hypothetical protein 2133715 9794606 AARI_18760 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917067.1 2133371 R 861360 CDS YP_003917068.1 308177662 9794607 complement(2133726..2134484) 1 NC_014550.1 the SUF system of E. coli and Erwinia chrysanthemi is important for Fe-S biogenesis under stressful conditions. The SUF system is made of six proteins: SufC is an atypical cytoplasmic ABC-ATPase, which forms a complex with SufB and SufD; SufA plays the role of a scaffold protein for assembly of iron-sulfur clusters and delivery to target proteins; SufS is a cysteine desulfurase which mobilizes the sulfur atom from cysteine and provides it to the cluster; SufE has no associated function yet; FeS assembly ATPase SufC 2134484 sufC 9794607 sufC Arthrobacter arilaitensis Re117 FeS assembly ATPase SufC YP_003917068.1 2133726 R 861360 CDS YP_003917069.1 308177663 9794414 complement(2134545..2135825) 1 NC_014550.1 the SUF system of E. coli and Erwinia chrysanthemi is important for Fe-S biogenesis under stressful conditions. The SUF system is made of six proteins: SufC is an atypical cytoplasmic ABC-ATPase, which forms a complex with SufB and SufD; SufA plays the role of a scaffold protein for assembly of iron-sulfur clusters and delivery to target proteins; SufS is a cysteine desulfurase which mobilizes the sulfur atom from cysteine and provides it to the cluster; SufE has no associated function yet; FeS assembly protein SufD 2135825 sufD 9794414 sufD Arthrobacter arilaitensis Re117 FeS assembly protein SufD YP_003917069.1 2134545 R 861360 CDS YP_003917070.1 308177664 9794415 complement(2135828..2137288) 1 NC_014550.1 the SUF system of E. coli and Erwinia chrysanthemi is important for Fe-S biogenesis under stressful conditions. The SUF system is made of six proteins: SufC is an atypical cytoplasmic ABC-ATPase, which forms a complex with SufB and SufD; SufA plays the role of a scaffold protein for assembly of iron-sulfur clusters and delivery to target proteins; SufS is a cysteine desulfurase which mobilizes the sulfur atom from cysteine and provides it to the cluster; SufE has no associated function yet; FeS assembly protein SufB 2137288 sufB 9794415 sufB Arthrobacter arilaitensis Re117 FeS assembly protein SufB YP_003917070.1 2135828 R 861360 CDS YP_003917071.1 308177665 9794413 complement(2137285..2138070) 1 NC_014550.1 transcriptional regulator 2138070 9794413 AARI_18800 Arthrobacter arilaitensis Re117 transcriptional regulator YP_003917071.1 2137285 R 861360 CDS YP_003917072.1 308177666 9794608 2138262..2139215 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, drug exporter-1 (DrugE1) family (TC 3.A.1.105.z). ABCISSE: ABC transporter, ATP-binding protein (ABC), DRA-family (Drug and Antibiotic resistance), DRR-subfamily (Polyketide drug resistance). The typical organization of DRR systems consists of 1 ABC transporter (ABC) and 1 or 2 permeases (IM). Possible function in drug efflux; ABC drug resistance transporter, ATP-binding subunit 2139215 9794608 AARI_18810 Arthrobacter arilaitensis Re117 ABC drug resistance transporter, ATP-binding subunit YP_003917072.1 2138262 D 861360 CDS YP_003917073.1 308177667 9794609 2139212..2139976 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, drug exporter-1 (DrugE1) family (TC 3.A.1.105.z). ABCISSE: ABC transporter, permease (IM), DRA-family (Drug and Antibiotic resistance), DRR-subfamily (Polyketide drug resistance). The typical organization of DRR systems consists of 1 ABC transporter (ABC) and 1 or 2 permeases (IM). Possible function in drug efflux; ABC drug resistance transporter, inner membrane subunit 2139976 9794609 AARI_18820 Arthrobacter arilaitensis Re117 ABC drug resistance transporter, inner membrane subunit YP_003917073.1 2139212 D 861360 CDS YP_003917074.1 308177668 9794610 2140007..2140945 1 NC_014550.1 identified by match to protein family PF02628. One member of this family, CtaA, is required for cytochrome aa3 biosynthesis in Bacillus subtilis; cytochrome oxidase assembly protein 2140945 9794610 AARI_18830 Arthrobacter arilaitensis Re117 cytochrome oxidase assembly protein YP_003917074.1 2140007 D 861360 CDS YP_003917075.1 308177669 9794611 complement(2141014..2141961) 1 NC_014550.1 6 transmembranes helices predicted by TMHMM2.0; hypothetical protein 2141961 9794611 AARI_18840 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917075.1 2141014 R 861360 CDS YP_003917076.1 308177670 9794612 complement(2141945..2142295) 1 NC_014550.1 identified by match to protein family PF03551; PadR-like family transcriptional regulator 2142295 9794612 AARI_18850 Arthrobacter arilaitensis Re117 PadR-like family transcriptional regulator YP_003917076.1 2141945 R 861360 CDS YP_003917077.1 308177671 9794613 complement(2142509..2143411) 1 NC_014550.1 converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group; protoheme IX farnesyltransferase 2143411 cyoE 9794613 cyoE Arthrobacter arilaitensis Re117 protoheme IX farnesyltransferase YP_003917077.1 2142509 R 861360 CDS YP_003917078.1 308177672 9793774 2144269..2146383 1 NC_014550.1 catalyzes the reversible transfer of a two-carbon ketol unit from xylulose 5-phosphate to ribose 5- phosphate, to form sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate. The second reaction catalyzed by transketolase involves the transfer of a 2-carbon fragment from D-xylulose 5-phosphate to the aldose D- erythrose-4-phosphate, affording fructose-6-phosphate and glyceraldehyde 3-phosphate; transketolase 2146383 tkt 9793774 tkt Arthrobacter arilaitensis Re117 transketolase YP_003917078.1 2144269 D 861360 CDS YP_003917079.1 308177673 9794455 2146402..2147505 1 NC_014550.1 catalyzes the reversible formation of D-erythrose 4- phosphate and D-fructose 6-phosphate from sedoheptulose 7- phosphate and D-glyceraldehyde 3-phosphate; transaldolase 2147505 tal 9794455 tal Arthrobacter arilaitensis Re117 transaldolase YP_003917079.1 2146402 D 861360 CDS YP_003917080.1 308177674 9794423 2147506..2149080 1 NC_014550.1 catalyzes the reversible isomerization of glucose-6- phosphate to fructose-6-phosphate. Also catalyzes the anomerization of D-glucose-6-phosphate; glucose-6-phosphate isomerase 2149080 pgi 9794423 pgi Arthrobacter arilaitensis Re117 glucose-6-phosphate isomerase YP_003917080.1 2147506 D 861360 CDS YP_003917081.1 308177675 9794197 2149087..2150607 1 NC_014550.1 catalyzes the first step in the pentose phosphate pathway, the reduction of glucose-6-phosphate to gluconolactone-6-phosphate; glucose-6-phosphate 1-dehydrogenase 2150607 zwf 9794197 zwf Arthrobacter arilaitensis Re117 glucose-6-phosphate 1-dehydrogenase YP_003917081.1 2149087 D 861360 CDS YP_003917082.1 308177676 9794518 2150604..2151545 1 NC_014550.1 subunit of glucose-6-phosphate 1- dehydrogenase; OpcA protein 2151545 opcA 9794518 opcA Arthrobacter arilaitensis Re117 OpcA protein YP_003917082.1 2150604 D 861360 CDS YP_003917083.1 308177677 9794157 2151535..2152275 1 NC_014550.1 involved in the pentose phosphate pathway. Catalyzes the hydrolysis of 6-phosphogluconolactone to 6- phosphogluconate; 6-phosphogluconolactonase 2152275 pgl 9794157 pgl Arthrobacter arilaitensis Re117 6-phosphogluconolactonase YP_003917083.1 2151535 D 861360 CDS YP_003917084.1 308177678 9794199 2152357..2153322 1 NC_014550.1 catalyzes the oxidative deamination of D-amino acids to the corresponding keto acids, producing ammonia and hydrogen peroxide as by-products; D-amino-acid oxidase 2153322 dao 9794199 dao Arthrobacter arilaitensis Re117 D-amino-acid oxidase YP_003917084.1 2152357 D 861360 CDS YP_003917085.1 308177679 9793787 2153669..2156107 1 NC_014550.1 the members of this family catalyse the formation of glucose 1-phosphate from one of the following polyglucoses: glycogen, starch, glucan or maltodextrin; phosphorylase 2156107 glgP 9793787 glgP Arthrobacter arilaitensis Re117 phosphorylase YP_003917085.1 2153669 D 861360 CDS YP_003917086.1 308177680 9793902 2156218..2158410 1 NC_014550.1 catalyzes the formation of alpha-1,6 branch points in either glycogen or starch by cleavage of the alpha-1,4 glucosidic linkage, yielding a non-reducing end oligosaccharide chain and subsequent attachment to the alpha-1,6 position; 1,4-alpha-glucan branching enzyme 2158410 glgB 9793902 glgB Arthrobacter arilaitensis Re117 1,4-alpha-glucan branching enzyme YP_003917086.1 2156218 D 861360 CDS YP_003917087.1 308177681 9793900 2158407..2159741 1 NC_014550.1 catalyzes an important step in the biosynthesis of alpha 1,4-glucans (glycogen or starch) in bacteria and plants: synthesis of the activated glucosyl donor, ADP- glucose, from glucose-1-phosphate and ATP; glucose-1-phosphate adenylyltransferase 2159741 glgC 9793900 glgC Arthrobacter arilaitensis Re117 glucose-1-phosphate adenylyltransferase YP_003917087.1 2158407 D 861360 CDS YP_003917088.1 308177682 9793901 2159748..2161196 1 NC_014550.1 involved in glycogen synthesis from ADP-glucose; bacterial glycogen synthase 2161196 glgA 9793901 glgA Arthrobacter arilaitensis Re117 bacterial glycogen synthase YP_003917088.1 2159748 D 861360 CDS YP_003917089.1 308177683 9794615 complement(2163392..2163643) 1 NC_014550.1 identified by match to protein family PF03840. The translocase itself comprises 7 proteins, including a chaperone protein (SecB), an ATPase (SecA), an integral membrane complex (SecCY, SecE and SecG), and two additional membrane proteins that promote the release of the mature peptide into the periplasm (SecD and SecF); protein-export membrane protein SecG 2163643 secG 9794615 secG Arthrobacter arilaitensis Re117 protein-export membrane protein SecG YP_003917089.1 2163392 R 861360 CDS YP_003917090.1 308177684 9794390 complement(2163666..2164481) 1 NC_014550.1 catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate; triosephosphate isomerase 2164481 tpiA 9794390 tpiA Arthrobacter arilaitensis Re117 triosephosphate isomerase YP_003917090.1 2163666 R 861360 CDS YP_003917091.1 308177685 9794458 complement(2164485..2165714) 1 NC_014550.1 catalyzes the transfer of the high-energy phosphate group of 1,3-bisphosphoglycerate to ADP, forming ATP and 3- phosphoglycerate; phosphoglycerate kinase 2165714 pgk 9794458 pgk Arthrobacter arilaitensis Re117 phosphoglycerate kinase YP_003917091.1 2164485 R 861360 CDS YP_003917092.1 308177686 9794198 complement(2165731..2166738) 1 NC_014550.1 catalyses the reversible oxidation and phosphorylation of D-glyceraldehyde-3-phosphate to 1,3- diphospho-glycerate; glyceraldehyde-3-phosphate dehydrogenase 2166738 gap 9794198 gap Arthrobacter arilaitensis Re117 glyceraldehyde-3-phosphate dehydrogenase YP_003917092.1 2165731 R 861360 CDS YP_003917093.1 308177687 9793885 complement(2166923..2167552) 1 NC_014550.1 catalyses the conversion of superoxide radicals to hydrogen peroxide and molecular oxygen; superoxide dismutase 2167552 sodA 9793885 sodA Arthrobacter arilaitensis Re117 superoxide dismutase YP_003917093.1 2166923 R 861360 CDS YP_003917094.1 308177688 9794399 complement(2167613..2168593) 1 NC_014550.1 hypothetical protein 2168593 9794399 AARI_19050 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917094.1 2167613 R 861360 CDS YP_003917095.1 308177689 9794616 complement(2168621..2169646) 1 NC_014550.1 match to PF1933: uncharacterised protein family UPF0052; hypothetical protein 2169646 9794616 AARI_19060 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917095.1 2168621 R 861360 CDS YP_003917096.1 308177690 9794617 complement(2169652..2170545) 1 NC_014550.1 match to PF1933. This family contains an ATP- binding site and could be an ATPase; P-loop ATPase protein 2170545 9794617 AARI_19070 Arthrobacter arilaitensis Re117 P-loop ATPase protein YP_003917096.1 2169652 R 861360 CDS YP_003917097.1 308177691 9794618 complement(2170555..2172498) 1 NC_014550.1 excinuclease ABC catalyses nucleotide excision repair in a multi-step process; excinuclease ABC subunit C 2172498 uvrC 9794618 uvrC Arthrobacter arilaitensis Re117 excinuclease ABC subunit C YP_003917097.1 2170555 R 861360 CDS YP_003917098.1 308177692 9794499 complement(2172502..2173173) 1 NC_014550.1 1-acylglycerol-3-phosphate O-acyltransferase catalyzes the following reaction: Acyl-CoA + 1-acyl-sn- glycerol 3-phosphate <=> CoA + 1,2-diacyl-sn-glycerol 3- phosphate. It is involved in phospholipid biosynthesis; 1-acylglycerol-3-phosphate O-acyltransferase 2173173 9794499 AARI_19090 Arthrobacter arilaitensis Re117 1-acylglycerol-3-phosphate O-acyltransferase YP_003917098.1 2172502 R 861360 CDS YP_003917099.1 308177693 9794619 complement(2173174..2173863) 1 NC_014550.1 identified by match to PF00702. This family includes L-2-haloacid dehalogenase, epoxide hydrolases and phosphatases; haloacid dehalogenase 2173863 9794619 AARI_19100 Arthrobacter arilaitensis Re117 haloacid dehalogenase YP_003917099.1 2173174 R 861360 CDS YP_003917100.1 308177694 9794620 complement(2173965..2176793) 1 NC_014550.1 excinuclease ABC catalyses nucleotide excision repair in a multi-step process; excinuclease ABC subunit A 2176793 uvrA 9794620 uvrA Arthrobacter arilaitensis Re117 excinuclease ABC subunit A YP_003917100.1 2173965 R 861360 CDS YP_003917101.1 308177695 9794496 complement(2176974..2177351) 1 NC_014550.1 transcriptional regulator 2177351 9794496 AARI_19120 Arthrobacter arilaitensis Re117 transcriptional regulator YP_003917101.1 2176974 R 861360 CDS YP_003917102.1 308177696 9794621 2177434..2178087 1 NC_014550.1 identified by match to PF00753: metallo-beta- lactamase superfamily. Apart from the beta-lactamases, a number of other proteins contain this domain. These proteins include thiolesterases, members of the glyoxalase II family, that catalyse the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid and a competence protein that is essential for natural transformation in Neisseria gonorrhoeae and could be a transporter involved in DNA uptake; metallo-beta-lactamase 2178087 9794621 AARI_19130 Arthrobacter arilaitensis Re117 metallo-beta-lactamase YP_003917102.1 2177434 D 861360 CDS YP_003917103.1 308177697 9794622 complement(2178162..2178953) 1 NC_014550.1 catalyzes the monomethyl esterification of trans- aconitate and related compounds. Possible role in detoxifying trans-aconitate; trans-aconitate 2-methyltransferase 2178953 tam 9794622 tam Arthrobacter arilaitensis Re117 trans-aconitate 2-methyltransferase YP_003917103.1 2178162 R 861360 CDS YP_003917104.1 308177698 9794424 2179031..2181562 1 NC_014550.1 possible DNA or RNA helicase; ATP-dependent helicase 2181562 9794424 AARI_19150 Arthrobacter arilaitensis Re117 ATP-dependent helicase YP_003917104.1 2179031 D 861360 CDS YP_003917105.1 308177699 9794623 2181565..2182020 1 NC_014550.1 identified by match to PF00293. Members of the Nudix hydrolase superfamily catalyze the hydrolysis of nucleoside diphosphates linked to other moieties. Substrates of nudix hydrolases include intact and oxidatively damaged nucleoside triphosphates, dinucleoside polyphosphates, nucleotide-sugars and dinucleotide enzymes. These substrates are metabolites or cell signaling molecules that require regulation during different stages of the cell cycle or during periods of stress. In general, the role of the nudix hydrolase is to sanitize the nucleotide pools and to maintain cell viability, thereby serving as surveillance and house- cleaning enzymes; NUDIX hydrolase 2182020 9794623 AARI_19160 Arthrobacter arilaitensis Re117 NUDIX hydrolase YP_003917105.1 2181565 D 861360 CDS YP_003917106.1 308177700 9794624 2182093..2182284 1 NC_014550.1 hypothetical protein 2182284 9794624 AARI_19170 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917106.1 2182093 D 861360 CDS YP_003917107.1 308177701 9794625 complement(2182300..2183073) 1 NC_014550.1 hypothetical protein 2183073 9794625 AARI_19180 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917107.1 2182300 R 861360 CDS YP_003917108.1 308177702 9794626 complement(2183180..2184259) 1 NC_014550.1 transposase of ISAar29, IS110 family 2184259 9794626 AARI_35360 Arthrobacter arilaitensis Re117 transposase of ISAar29, IS110 family YP_003917108.1 2183180 R 861360 CDS YP_003917109.1 308177703 9793477 complement(2184378..2184632) 1 NC_014550.1 hypothetical protein 2184632 9793477 AARI_19190 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917109.1 2184378 R 861360 CDS YP_003917110.1 308177704 9794627 complement(2184684..2185436) 1 NC_014550.1 identified by match to PF04307: predicted membrane- bound metal-dependent hydrolase (DUF457); membrane-bound metal-dependent hydrolase 2185436 9794627 AARI_19200 Arthrobacter arilaitensis Re117 membrane-bound metal-dependent hydrolase YP_003917110.1 2184684 R 861360 CDS YP_003917111.1 308177705 9794628 2185499..2185987 1 NC_014550.1 identified by match to PF00583: acetyltransferase (GNAT) family; GNAT family acetyltransferase 2185987 9794628 AARI_19210 Arthrobacter arilaitensis Re117 GNAT family acetyltransferase YP_003917111.1 2185499 D 861360 CDS YP_003917112.1 308177706 9794629 2185987..2187270 1 NC_014550.1 releases N-terminal proline from a peptide; prolyl aminopeptidase 2187270 9794629 AARI_19220 Arthrobacter arilaitensis Re117 prolyl aminopeptidase YP_003917112.1 2185987 D 861360 CDS YP_003917113.1 308177707 9794630 complement(2187354..2187806) 1 NC_014550.1 identified by match to protein family PF01047. Regulators with the marR-type HTH domain are present in bacteria and archaea and control a variety of biological functions, including resistance to multiple antibiotics, household disinfectants, organic solvents, oxidative stress agents and regulation of the virulence factor synthesis in pathogens of humans and plants. Many of the marR-like regulators respond to aromatic compounds; MarR family transcriptional regulator 2187806 9794630 AARI_19230 Arthrobacter arilaitensis Re117 MarR family transcriptional regulator YP_003917113.1 2187354 R 861360 CDS YP_003917114.1 308177708 9794631 complement(2187910..2189049) 1 NC_014550.1 match to PF0371: TerC, Integral membrane protein TerC family. 9 transmembranes helices predicted by TMHMM2. 0; hypothetical protein 2189049 9794631 AARI_19240 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917114.1 2187910 R 861360 CDS YP_003917115.1 308177709 9794632 complement(2189175..2191262) 1 NC_014550.1 excinuclease ABC catalyses nucleotide excision repair in a multi-step process; excinuclease ABC subunit B 2191262 uvrB 9794632 uvrB Arthrobacter arilaitensis Re117 excinuclease ABC subunit B YP_003917115.1 2189175 R 861360 CDS YP_003917116.1 308177710 9794498 complement(2191336..2191584) 1 NC_014550.1 2 transmembrane helices predicted by TMHMM2.0; hypothetical protein 2191584 9794498 AARI_19260 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917116.1 2191336 R 861360 CDS YP_003917117.1 308177711 9794633 complement(2191587..2192183) 1 NC_014550.1 catalyzes the phosphorylation of the 3-hydroxyl group of dephosphocoenzyme A to form coenzyme A: ATP + dephospho-CoA = ADP + CoA; dephospho-CoA kinase 2192183 coaE 9794633 coaE Arthrobacter arilaitensis Re117 dephospho-CoA kinase YP_003917117.1 2191587 R 861360 CDS YP_003917118.1 308177712 9793750 2192209..2192883 1 NC_014550.1 match to PF01205: uncharacterized protein family UPF0029; hypothetical protein 2192883 9793750 AARI_19280 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917118.1 2192209 D 861360 CDS YP_003917119.1 308177713 9794634 2192880..2194091 1 NC_014550.1 match to protein domain PF05175. This domain is found in ribosomal RNA small subunit methyltransferase C as well as other methyltransferases; methyltransferase 2194091 9794634 AARI_19290 Arthrobacter arilaitensis Re117 methyltransferase YP_003917119.1 2192880 D 861360 CDS YP_003917120.1 308177714 9794635 2194153..2195799 1 NC_014550.1 hypothetical protein 2195799 9794635 AARI_19300 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917120.1 2194153 D 861360 CDS YP_003917121.1 308177715 9794636 complement(2195827..2197137) 1 NC_014550.1 6 transmembranes helices predicted by TMHMM2.0; hypothetical protein 2197137 9794636 AARI_19310 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917121.1 2195827 R 861360 CDS YP_003917122.1 308177716 9794637 complement(2197385..2198860) 1 NC_014550.1 binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence; 30S ribosomal protein S1 2198860 rpsA 9794637 rpsA Arthrobacter arilaitensis Re117 30S ribosomal protein S1 YP_003917122.1 2197385 R 861360 CDS YP_003917123.1 308177717 9794348 complement(2199077..2200390) 1 NC_014550.1 hypothetical protein 2200390 9794348 AARI_19330 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917123.1 2199077 R 861360 CDS YP_003917124.1 308177718 9794638 complement(2200459..2201361) 1 NC_014550.1 match to protein domain PF01522. This domain is found in polysaccharide deacetylase. This family of polysaccharide deacetylases includes NodB, which is a chitooligosaccharide deacetylase. It also includes chitin deacetylase from yeast and endoxylanases which hydrolyses glucosidic bonds in xylan; polysaccharide deacetylase domain-containing protein 2201361 9794638 AARI_19340 Arthrobacter arilaitensis Re117 polysaccharide deacetylase domain-containing protein YP_003917124.1 2200459 R 861360 CDS YP_003917125.1 308177719 9794639 complement(2201470..2204082) 1 NC_014550.1 DNA polymerase I 2204082 polA 9794639 polA Arthrobacter arilaitensis Re117 DNA polymerase I YP_003917125.1 2201470 R 861360 CDS YP_003917126.1 308177720 9794213 2204168..2204653 1 NC_014550.1 match to protein domain PF03061: thioesterase superfamily; thioesterase family domain-containing protein 2204653 9794213 AARI_19360 Arthrobacter arilaitensis Re117 thioesterase family domain-containing protein YP_003917126.1 2204168 D 861360 CDS YP_003917127.1 308177721 9794640 complement(2204747..2205292) 1 NC_014550.1 match to protein domain PF01872. This domain is found in the C-terminus of the bifunctional deaminase- reductase in combination with PF00383 as well as in isolation in some archaebacterial proteins; RibD domain-containing protein 2205292 9794640 AARI_19370 Arthrobacter arilaitensis Re117 RibD domain-containing protein YP_003917127.1 2204747 R 861360 CDS YP_003917128.1 308177722 9794641 complement(2205386..2205634) 1 NC_014550.1 2 transmembranes helices predicted by TMHMM2.0; hypothetical protein 2205634 9794641 AARI_19380 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917128.1 2205386 R 861360 CDS YP_003917129.1 308177723 9794642 complement(2205631..2206863) 1 NC_014550.1 inorganic phosphate transporter (PiT) family (TC 2. A.20.y.z); low-affinity inorganic phosphate transporter 2206863 pit 9794642 pit Arthrobacter arilaitensis Re117 low-affinity inorganic phosphate transporter YP_003917129.1 2205631 R 861360 CDS YP_003917130.1 308177724 9794207 complement(2207163..2207780) 1 NC_014550.1 response regulators are key elements in two- component signal transduction systems, which enable bacteria to sense, respond, and adapt to a wide range of environments, stressors, and growth conditions. Match to PF03861: ANTAR domain. ANTAR (AmiR and NasR transcription antitermination regulators) is an RNA-binding domain found in bacterial transcription antitermination regulatory proteins; two-component system response regulator 2207780 9794207 AARI_19400 Arthrobacter arilaitensis Re117 two-component system response regulator YP_003917130.1 2207163 R 861360 CDS YP_003917131.1 308177725 9793627 complement(2208228..2209751) 1 NC_014550.1 catalyses the conversion of phosphoenolpyruvate to pyruvate with the concomitant phosphorylation of ADP to ATP; pyruvate kinase 2209751 pyk 9793627 pyk Arthrobacter arilaitensis Re117 pyruvate kinase YP_003917131.1 2208228 R 861360 CDS YP_003917132.1 308177726 9794263 complement(2209826..2211295) 1 NC_014550.1 glutamate synthase participates in the ammonia assimilation process by catalyzing the formation of glutamate from glutamine and 2-oxoglutarate; glutamate synthase (NADPH) subunit beta 2211295 gltD 9794263 gltD Arthrobacter arilaitensis Re117 glutamate synthase (NADPH) subunit beta YP_003917132.1 2209826 R 861360 CDS YP_003917133.1 308177727 9793919 complement(2211288..2215907) 1 NC_014550.1 glutamate synthase participates in the ammonia assimilation process by catalyzing the formation of glutamate from glutamine and 2-oxoglutarate; glutamate synthase (NADPH) subunit alpha 2215907 gltB 9793919 gltB Arthrobacter arilaitensis Re117 glutamate synthase (NADPH) subunit alpha YP_003917133.1 2211288 R 861360 CDS YP_003917134.1 308177728 9793918 complement(2216481..2217521) 1 NC_014550.1 catalyzes the first step in lipoprotein biogenesis. It transfers the n-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins; prolipoprotein diacylglyceryl transferase 2217521 lgt 9793918 lgt Arthrobacter arilaitensis Re117 prolipoprotein diacylglyceryl transferase YP_003917134.1 2216481 R 861360 CDS YP_003917135.1 308177729 9794037 complement(2217521..2218303) 1 NC_014550.1 tryptophan synthase catalyzes the last step in the biosynthesis of tryptophan: the conversion of indoleglycerol phosphate and serine, to tryptophan and glyceraldehyde 3- phosphate. Also catalyzes the conversion of serine and indole into tryptophan and water, and of indoleglycerol phosphate into indole and glyceraldehyde phosphate; tryptophan synthase subunit alpha 2218303 trpA 9794037 trpA Arthrobacter arilaitensis Re117 tryptophan synthase subunit alpha YP_003917135.1 2217521 R 861360 CDS YP_003917136.1 308177730 9794466 complement(2218304..2219635) 1 NC_014550.1 tryptophan synthase catalyzes the last step in the biosynthesis of tryptophan: the conversion of indoleglycerol phosphate and serine, to tryptophan and glyceraldehyde 3- phosphate. Also catalyzes the conversion of serine and indole into tryptophan and water, and of indoleglycerol phosphate into indole and glyceraldehyde phosphate; tryptophan synthase subunit beta 2219635 trpB 9794466 trpB Arthrobacter arilaitensis Re117 tryptophan synthase subunit beta YP_003917136.1 2218304 R 861360 CDS YP_003917137.1 308177731 9794467 complement(2219744..2220568) 1 NC_014550.1 catalyzes the fourth step in the biosynthesis of tryptophan: the ring closure of 1-(2-carboxy-phenylamino)- 1-deoxyribulose into indol-3-glycerol-phosphate; indole-3-glycerol-phosphate synthase 2220568 trpC 9794467 trpC Arthrobacter arilaitensis Re117 indole-3-glycerol-phosphate synthase YP_003917137.1 2219744 R 861360 CDS YP_003917138.1 308177732 9794468 complement(2220570..2220818) 1 NC_014550.1 2 transmembranes helices predicted by TMHMM2.0; hypothetical protein 2220818 9794468 AARI_19480 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917138.1 2220570 R 861360 CDS YP_003917139.1 308177733 9794644 complement(2220976..2221566) 1 NC_014550.1 hypothetical protein 2221566 9794644 AARI_19490 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917139.1 2220976 R 861360 CDS YP_003917140.1 308177734 9794645 complement(2221563..2223134) 1 NC_014550.1 anthranilate synthase is the first enzyme in the branch pathway in tryptophane biosynthesis. It catalyzes the biosynthesis of anthranilate from chorismate and glutamine; anthranilate synthase component I 2223134 trpE 9794645 trpE Arthrobacter arilaitensis Re117 anthranilate synthase component I YP_003917140.1 2221563 R 861360 CDS YP_003917141.1 308177735 9794470 complement(2223215..2223616) 1 NC_014550.1 catalyses the following reaction: 1-(5- phosphoribosyl)-AMP + H(2)O <=> 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide. Involved in Histidine biosynthesis; phosphoribosyl-AMP cyclohydrolase 2223616 hisI 9794470 hisI Arthrobacter arilaitensis Re117 phosphoribosyl-AMP cyclohydrolase YP_003917141.1 2223215 R 861360 CDS YP_003917142.1 308177736 9793968 2223733..2224392 1 NC_014550.1 hypothetical protein 2224392 9793968 AARI_19520 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917142.1 2223733 D 861360 CDS YP_003917143.1 308177737 9794646 2224495..2224776 1 NC_014550.1 signal peptide predicted by SignalP 3.0 HMM (probability: 1.000) with cleavage site probability 0.654 between position 37 and 38; hypothetical protein 2224776 9794646 AARI_19530 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917143.1 2224495 D 861360 CDS YP_003917144.1 308177738 9794647 complement(2224800..2226077) 1 NC_014550.1 transposase of ISAar15, ISL3 family 2226077 9794647 AARI_35370 Arthrobacter arilaitensis Re117 transposase of ISAar15, ISL3 family YP_003917144.1 2224800 R 861360 CDS YP_003917145.1 308177739 9793478 complement(2226158..2227237) 1 NC_014550.1 transposase of ISAar16, IS110 family 2227237 9793478 AARI_35380 Arthrobacter arilaitensis Re117 transposase of ISAar16, IS110 family YP_003917145.1 2226158 R 861360 CDS YP_003917146.1 308177740 9793479 2227683..2227946 1 NC_014550.1 hypothetical protein 2227946 9793479 AARI_19540 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917146.1 2227683 D 861360 CDS YP_003917147.1 308177741 9794648 2228232..2228867 1 NC_014550.1 signal peptide predicted by SignalP 3.0 HMM (probability: 1.000) with cleavage site probability 0.727 between position 27 and 238; hypothetical protein 2228867 9794648 AARI_19550 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917147.1 2228232 D 861360 CDS YP_003917148.1 308177742 9794649 2228867..2229751 1 NC_014550.1 match to protein domain PF00801; PDK domain-containing protein 2229751 9794649 AARI_19560 Arthrobacter arilaitensis Re117 PDK domain-containing protein YP_003917148.1 2228867 D 861360 CDS YP_003917149.1 308177743 9794650 complement(2229804..2230574) 1 NC_014550.1 imidazole glycerol phosphate synthase converts N1- (5-phosphoribulosyl)-formimino-5-aminoimidazole-4- carboxamide ribonucleotide (PRFAR) to imidazole glycerol phosphate (ImGP) and 5-(5-aminoimidazole-4-carboxamide) ribonucleotide (AICAR). Involved in histidine biosynthesis; imidazole glycerol phosphate synthase, cyclase subunit 2230574 hisF 9794650 hisF Arthrobacter arilaitensis Re117 imidazole glycerol phosphate synthase, cyclase subunit YP_003917149.1 2229804 R 861360 CDS YP_003917150.1 308177744 9793965 complement(2230596..2231444) 1 NC_014550.1 catalyses the following reaction: 1-(5-phospho-D- ribosyl)-ATP + diphosphate <=> ATP + 5-phospho-alpha-D- ribose 1-diphosphate. Involved in histidine biosynthesis; ATP phosphoribosyltransferase 2231444 hisG 9793965 hisG Arthrobacter arilaitensis Re117 ATP phosphoribosyltransferase YP_003917150.1 2230596 R 861360 CDS YP_003917151.1 308177745 9793966 complement(2231586..2231849) 1 NC_014550.1 catalyses the following reaction: 1-(5- phosphoribosyl)-ATP + H(2)O <=> 1-(5-phosphoribosyl)-AMP + diphosphate. Involved in Histidine biosynthesis; phosphoribosyl-ATP diphosphatase 2231849 hisE 9793966 hisE Arthrobacter arilaitensis Re117 phosphoribosyl-ATP diphosphatase YP_003917151.1 2231586 R 861360 CDS YP_003917152.1 308177746 9793964 complement(2231922..2232413) 1 NC_014550.1 catalyzes the condensation of 5-amino-6-(1-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4- dihydrohy-2-butanone-4-phosphate yielding 6,7-dimethyl-8- lumazine; riboflavin synthase subunit beta 2232413 ribH 9793964 ribH Arthrobacter arilaitensis Re117 riboflavin synthase subunit beta YP_003917152.1 2231922 R 861360 CDS YP_003917153.1 308177747 9794300 complement(2232450..2233706) 1 NC_014550.1 3,4-dihydroxy-2-butanone-4-phosphate synthase (4.1. 99.12) catalyses the following reaction: D-ribulose 5- phosphate <=> formate + L-3,4-dihydroxybutan-2-one 4- phosphate. GTP cyclohydrolase II (3.5.4.25) catalyses the following reaction:GTP + 3 H(2)O <=> formate + 2, 5-diamino- 6-hydroxy-4-(5-phosphoribosylamino)pyrimidine + diphosphate; bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II 2233706 ribBA 9794300 ribBA Arthrobacter arilaitensis Re117 bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II YP_003917153.1 2232450 R 861360 CDS YP_003917154.1 308177748 9794295 complement(2233706..2234329) 1 NC_014550.1 catalyzes the biosynthesis of riboflavin (vitamin B2) by dismutation of 6,7-dimethyl-8-(1-D-ribityl)lumazine (Lum): 2 6,7-dimethyl-8-(1-D-ribityl)lumazine => riboflavin + 4-(1-D-ribitylamino)-5-amino-2,6- dihydroxypyrimidine; riboflavin synthase subunit alpha 2234329 ribE 9794295 ribE Arthrobacter arilaitensis Re117 riboflavin synthase subunit alpha YP_003917154.1 2233706 R 861360 CDS YP_003917155.1 308177749 9794297 complement(2234365..2235405) 1 NC_014550.1 EC 3.5.4.26 catalyses the following reaction: 2,5- diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine + H2O = 5-amino-6-(5-phosphoribosylamino)uracil + NH3. EC 1. 1.1.193 catalyses the following reaction: 5-amino-6-(5- phosphoribitylamino)uracil + NADP+ = 5-amino-6-(5- phosphoribosylamino)uracil + NADPH; bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino) uracil reductase 2235405 ribD 9794297 ribD Arthrobacter arilaitensis Re117 bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino) uracil reductase YP_003917155.1 2234365 R 861360 CDS YP_003917156.1 308177750 9794296 complement(2235417..2236118) 1 NC_014550.1 Nicotinamide Ribonucleoside (NR) Uptake Permease (PnuC) family (TC 4.B.1.y.z). PnuC of Salmonella typhimurium and Haemophilus influenzae are believed to function cooperatively with NadR homologues, multifunctional proteins that together with PnuC, participate in Nicotinamide Ribonucleoside phosphorylation, transport and transcriptional regulation; nicotinamide ribonucleoside transporter PnuC 2236118 pnucC 9794296 pnucC Arthrobacter arilaitensis Re117 nicotinamide ribonucleoside transporter PnuC YP_003917156.1 2235417 R 861360 CDS YP_003917157.1 308177751 9794211 complement(2236415..2237077) 1 NC_014550.1 involved in the pentose phosphate pathway. Catalyzes the interconversion of D-ribulose 5-phosphate to D-xylulose 5-phosphate; ribulose-phosphate 3-epimerase 2237077 rpe 9794211 rpe Arthrobacter arilaitensis Re117 ribulose-phosphate 3-epimerase YP_003917157.1 2236415 R 861360 CDS YP_003917158.1 308177752 9794307 complement(2237106..2238629) 1 NC_014550.1 RNA methyltransferase 2238629 9794307 AARI_19660 Arthrobacter arilaitensis Re117 RNA methyltransferase YP_003917158.1 2237106 R 861360 CDS YP_003917159.1 308177753 9794651 complement(2238626..2239558) 1 NC_014550.1 catalyses the following reaction : 10- formyltetrahydrofolate + L-methionyl-tRNA(fMet) + H(2)O => tetrahydrofolate + N-formylmethionyl-tRNA(fMet). Involved in initiation of protein biosynthesis; methionyl-tRNA formyltransferase 2239558 fmt 9794651 fmt Arthrobacter arilaitensis Re117 methionyl-tRNA formyltransferase YP_003917159.1 2238626 R 861360 CDS YP_003917160.1 308177754 9793855 complement(2239562..2240125) 1 NC_014550.1 involved in polypeptide synthesis by removal of the formyl-group from methionine in growing polypeptides; peptide deformylase 2240125 def 9793855 def Arthrobacter arilaitensis Re117 peptide deformylase YP_003917160.1 2239562 R 861360 CDS YP_003917161.1 308177755 9793801 complement(2240219..2241019) 1 NC_014550.1 hypothetical protein 2241019 9793801 AARI_19690 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917161.1 2240219 R 861360 CDS YP_003917162.1 308177756 9793634 2242243..2242446 1 NC_014550.1 hypothetical protein 2242446 9793634 AARI_19700 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917162.1 2242243 D 861360 CDS YP_003917163.1 308177757 9794655 complement(2243802..2244842) 1 NC_014550.1 identified by match to PF03969; AFG1-like ATPase 2244842 9794655 AARI_19730 Arthrobacter arilaitensis Re117 AFG1-like ATPase YP_003917163.1 2243802 R 861360 CDS YP_003917164.1 308177758 9794656 2245058..2245972 1 NC_014550.1 thiosulfate sulfurtransferase-like protein 2245972 9794656 AARI_19740 Arthrobacter arilaitensis Re117 thiosulfate sulfurtransferase-like protein YP_003917164.1 2245058 D 861360 CDS YP_003917165.1 308177759 9794657 2245969..2246409 1 NC_014550.1 identified by match to PF02657. This family consists of the SufE-related proteins. These have been implicated in Fe-S metabolism and export; SufE-like protein 2246409 9794657 AARI_19750 Arthrobacter arilaitensis Re117 SufE-like protein YP_003917165.1 2245969 D 861360 CDS YP_003917166.1 308177760 9794658 2246464..2246967 1 NC_014550.1 match to PF04073: YbaK / prolyl-tRNA synthetases associated domain. This domain of unknown function is found in numerous prokaryote organisms. The structure of YbaK shows a novel fold. This domain also occurs in a number of prolyl-tRNA synthetases (proRS) from prokaryotes. Thus, the domain is thought to be involved in oligo-nucleotide binding, with possible roles in recognition/discrimination or editing of prolyl-tRNA; YbaK domain-containing protein 2246967 9794658 AARI_19760 Arthrobacter arilaitensis Re117 YbaK domain-containing protein YP_003917166.1 2246464 D 861360 CDS YP_003917167.1 308177761 9794659 2247092..2247403 1 NC_014550.1 hypothetical protein 2247403 9794659 AARI_19770 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917167.1 2247092 D 861360 CDS YP_003917168.1 308177762 9794660 complement(2247449..2248669) 1 NC_014550.1 match to PS00120 pattern: lipases, serine active site; lipase/esterase 2248669 9794660 AARI_19780 Arthrobacter arilaitensis Re117 lipase/esterase YP_003917168.1 2247449 R 861360 CDS YP_003917169.1 308177763 9794661 2248732..2249175 1 NC_014550.1 plays a role in preventing oxidative-stress damage caused by reactive oxygen species by reducing the oxidized form of methionine back to methionine and thereby reactivating peptides that had been damaged; peptide-methionine (R)-S-oxide reductase 2249175 msrB 9794661 msrB Arthrobacter arilaitensis Re117 peptide-methionine (R)-S-oxide reductase YP_003917169.1 2248732 D 861360 CDS YP_003917170.1 308177764 9794112 2249324..2250709 1 NC_014550.1 hypothetical protein 2250709 9794112 AARI_19800 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917170.1 2249324 D 861360 CDS YP_003917171.1 308177765 9794662 2250753..2251436 1 NC_014550.1 identified by match to PF00106. The short-chain dehydrogenases/reductases family (SDR) is a very large family of enzymes, most of which are known to be NAD- or NADP-dependent oxidoreductases; short-chain dehydrogenases/reductases family protein 2251436 9794662 AARI_19810 Arthrobacter arilaitensis Re117 short-chain dehydrogenases/reductases family protein YP_003917171.1 2250753 D 861360 CDS YP_003917172.1 308177766 9794663 2251518..2252579 1 NC_014550.1 catalyses the production of glycine and acetaldehyde from threonine; threonine aldolase 2252579 9794663 AARI_19820 Arthrobacter arilaitensis Re117 threonine aldolase YP_003917172.1 2251518 D 861360 CDS YP_003917173.1 308177767 9794664 2252641..2253279 1 NC_014550.1 hypothetical protein 2253279 9794664 AARI_19830 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917173.1 2252641 D 861360 CDS YP_003917174.1 308177768 9794665 2253326..2254576 1 NC_014550.1 ribonuclease D cleaves multimeric tRNA precursor at the spacer region. Contribute to the 3 prime maturation of several stable RNA; ribonuclease D 2254576 9794665 AARI_19840 Arthrobacter arilaitensis Re117 ribonuclease D YP_003917174.1 2253326 D 861360 CDS YP_003917175.1 308177769 9794666 2254736..2255986 1 NC_014550.1 also named acetyl-CoA C-acyltransferase. Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed. Involved in the aerobic and anaerobic degradation of long-chain fatty acids. Part of the FadAB fatty acid oxidation complex; fatty acid oxidation complex subunit beta 2255986 fadA 9794666 fadA Arthrobacter arilaitensis Re117 fatty acid oxidation complex subunit beta YP_003917175.1 2254736 D 861360 CDS YP_003917176.1 308177770 9793842 2255997..2258120 1 NC_014550.1 identified by similarity to protein SP: P21177 (Escherichia coli). Catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities. Involved in the aerobic and anaerobic degradation of long-chain fatty acids. Part of the FadAB fatty acid oxidation complex; fatty acid oxidation complex subunit alpha 2258120 fadB 9793842 fadB Arthrobacter arilaitensis Re117 fatty acid oxidation complex subunit alpha YP_003917176.1 2255997 D 861360 CDS YP_003917177.1 308177771 9793844 complement(2258365..2258496) 1 NC_014550.1 hypothetical protein 2258496 9793844 AARI_19870 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917177.1 2258365 R 861360 CDS YP_003917178.1 308177772 9794667 complement(2258496..2260187) 1 NC_014550.1 Solute:Sodium Symporter (SSS) family (2.A.21.y.z). Members of the SSS family catalyze solute:Na+ symport. The solutes transported may be sugars, amino acids, organo cations such as choline, nucleosides, inositols, vitamins, urea or anions, depending on the system; Na+/solute symporter 2260187 9794667 AARI_19880 Arthrobacter arilaitensis Re117 Na+/solute symporter YP_003917178.1 2258496 R 861360 CDS YP_003917179.1 308177773 9794668 2261184..2261657 1 NC_014550.1 match to protein domain PF00355; Rieske (2Fe-2S) domain-containing protein 2261657 9794668 AARI_19890 Arthrobacter arilaitensis Re117 Rieske (2Fe-2S) domain-containing protein YP_003917179.1 2261184 D 861360 CDS YP_003917180.1 308177774 9794669 complement(2261733..2262743) 1 NC_014550.1 identified by match to PF00248 family: Aldo/keto reductase family. This family includes a number of K+ ion channel beta chain regulatory domains - these are reported to have oxidoreductase activity; aldo-keto reductase family protein 2262743 9794669 AARI_19900 Arthrobacter arilaitensis Re117 aldo-keto reductase family protein YP_003917180.1 2261733 R 861360 CDS YP_003917181.1 308177775 9794670 2262843..2264270 1 NC_014550.1 catalyzes the penultimate step in arginine biosynthesis: the ATP-dependent ligation of citrulline to aspartate to form argininosuccinate, AMP and pyrophosphate; argininosuccinate synthase 2264270 argG 9794670 argG Arthrobacter arilaitensis Re117 argininosuccinate synthase YP_003917181.1 2262843 D 861360 CDS YP_003917182.1 308177776 9793677 complement(2264417..2264752) 1 NC_014550.1 hypothetical protein 2264752 9793677 AARI_19920 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917182.1 2264417 R 861360 CDS YP_003917183.1 308177777 9794671 complement(2264774..2265235) 1 NC_014550.1 hypothetical protein 2265235 9794671 AARI_19930 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917183.1 2264774 R 861360 CDS YP_003917184.1 308177778 9794672 complement(2265272..2265841) 1 NC_014550.1 hypothetical protein 2265841 9794672 AARI_19940 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917184.1 2265272 R 861360 CDS YP_003917185.1 308177779 9794673 complement(2265870..2266490) 1 NC_014550.1 hypothetical protein 2266490 9794673 AARI_19950 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917185.1 2265870 R 861360 CDS YP_003917186.1 308177780 9794674 complement(2266487..2268454) 1 NC_014550.1 catalyzes the thiamine pyrophosphoate-dependent acyloin condensation reaction between carbon atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1- deoxy-D-xylulose-5-phosphate, a precursor in the biosynthetic pathway to isoprenoids, thiamine (vitamin B1), and pyridoxal (vitamin B6); 1-deoxy-D-xylulose-5-phosphate synthase 2268454 dxs 9794674 dxs Arthrobacter arilaitensis Re117 1-deoxy-D-xylulose-5-phosphate synthase YP_003917186.1 2266487 R 861360 CDS YP_003917187.1 308177781 9793832 complement(2268572..2269477) 1 NC_014550.1 match to PF01636. This family consists of bacterial antibiotic resistance proteins, which confer resistance to various aminoglycosides. The aminoglycoside phosphotransferases inactivate aminoglycoside antibiotics via phosphorylation. This family also includes homoserine kinase; phosphotransferase 2269477 9793832 AARI_19970 Arthrobacter arilaitensis Re117 phosphotransferase YP_003917187.1 2268572 R 861360 CDS YP_003917188.1 308177782 9794675 2269581..2270195 1 NC_014550.1 identified by match to protein domain PF08241; SAM-dependent methyltransferase 2270195 9794675 AARI_19980 Arthrobacter arilaitensis Re117 SAM-dependent methyltransferase YP_003917188.1 2269581 D 861360 CDS YP_003917189.1 308177783 9794676 complement(2270294..2273002) 1 NC_014550.1 catalyzes the reversible isomerization of citrate and isocitrate. Cis-aconitate is formed as an intermediary product during the course of the reaction; aconitate hydratase 2273002 acn 9794676 acn Arthrobacter arilaitensis Re117 aconitate hydratase YP_003917189.1 2270294 R 861360 CDS YP_003917190.1 308177784 9793650 complement(2273194..2274516) 1 NC_014550.1 RNA methyltransferase 2274516 9793650 AARI_20000 Arthrobacter arilaitensis Re117 RNA methyltransferase YP_003917190.1 2273194 R 861360 CDS YP_003917191.1 308177785 9794677 complement(2274541..2276541) 1 NC_014550.1 11 transmembrane helices predicted by TMHMM2.0; hypothetical protein 2276541 9794677 AARI_20010 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917191.1 2274541 R 861360 CDS YP_003917192.1 308177786 9794678 2276687..2277364 1 NC_014550.1 voltage-gated K+ Channel beta-subunit family, TrkA regulatory subunit of TrkH and TrkG (TC 8.A.5.2.1). Part of a potassium transport system (regulatory subunit). TrkA domains can bind NAD+ and NADH, possibly allowing K+ transporters to be responsive to the redox state of the cell. Systems regulated by TrkA include TrkG/H (TC 2.A.38. 1.1); Trk system potassium uptake protein TrkA 2277364 trkA 9794678 trkA Arthrobacter arilaitensis Re117 Trk system potassium uptake protein TrkA YP_003917192.1 2276687 D 861360 CDS YP_003917193.1 308177787 9794460 2277380..2278045 1 NC_014550.1 voltage-gated K+ Channel beta-subunit family, TrkA regulatory subunit of TrkH and TrkG (TC 8.A.5.2.1). Part of a potassium transport system (regulatory subunit). TrkA domains can bind NAD+ and NADH, possibly allowing K+ transporters to be responsive to the redox state of the cell. Systems regulated by TrkA include TrkG/H (TC 2.A.38. 1.1); Trk system potassium uptake protein TrkA 2278045 trkA 9794460 trkA Arthrobacter arilaitensis Re117 Trk system potassium uptake protein TrkA YP_003917193.1 2277380 D 861360 CDS YP_003917194.1 308177788 9794461 complement(2278042..2278770) 1 NC_014550.1 6 transmembranes helices predicted by TMHMM2.0; hypothetical protein 2278770 9794461 AARI_20040 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917194.1 2278042 R 861360 CDS YP_003917195.1 308177789 9794679 complement(2278833..2279207) 1 NC_014550.1 hypothetical protein 2279207 9794679 AARI_20050 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917195.1 2278833 R 861360 CDS YP_003917196.1 308177790 9794680 complement(2279211..2279900) 1 NC_014550.1 hypothetical protein 2279900 9794680 AARI_20060 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917196.1 2279211 R 861360 CDS YP_003917197.1 308177791 9794681 complement(2279939..2280397) 1 NC_014550.1 removes dUTP from the nucleotide triphosphate pool and therefore prevents the incorporation of uracil into the DNA; dUTP diphosphatase 2280397 dut 9794681 dut Arthrobacter arilaitensis Re117 dUTP diphosphatase YP_003917197.1 2279939 R 861360 CDS YP_003917198.1 308177792 9793830 2280539..2281072 1 NC_014550.1 2 transmembranes helices predicted by TMHMM2.0; hypothetical protein 2281072 9793830 AARI_20080 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917198.1 2280539 D 861360 CDS YP_003917199.1 308177793 9794682 complement(2281164..2281463) 1 NC_014550.1 hypothetical protein 2281463 9794682 AARI_20090 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917199.1 2281164 R 861360 CDS YP_003917200.1 308177794 9794683 2281726..2282793 1 NC_014550.1 hypothetical protein 2282793 9794683 AARI_20100 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917200.1 2281726 D 861360 CDS YP_003917201.1 308177795 9794684 complement(2282883..2284067) 1 NC_014550.1 match to protein family PF01663. This family consists of phosphodiesterases. They catalyse the cleavage of phosphodiester and phosphosulfate bonds in NAD, deoxynucleotides and nucleotide sugars; type I phosphodiesterase / nucleotide pyrophosphatase 2284067 9794684 AARI_20110 Arthrobacter arilaitensis Re117 type I phosphodiesterase / nucleotide pyrophosphatase YP_003917201.1 2282883 R 861360 CDS YP_003917202.1 308177796 9794685 complement(2284070..2284657) 1 NC_014550.1 hypothetical protein 2284657 9794685 AARI_20120 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917202.1 2284070 R 861360 CDS YP_003917203.1 308177797 9794686 complement(2284709..2287369) 1 NC_014550.1 identified by match to PF00583: acetyltransferase (GNAT) family; GNAT family acetyltransferase 2287369 9794686 AARI_20130 Arthrobacter arilaitensis Re117 GNAT family acetyltransferase YP_003917203.1 2284709 R 861360 CDS YP_003917204.1 308177798 9794687 2287468..2290101 1 NC_014550.1 DNA gyrase negatively supercoils closed circular double-stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings. Made up of two chains. The A chain is responsible for DNA breakage and rejoining; the B chain catalyzes ATP hydrolysis; DNA gyrase subunit A 2290101 9794687 AARI_20140 Arthrobacter arilaitensis Re117 DNA gyrase subunit A YP_003917204.1 2287468 D 861360 CDS YP_003917205.1 308177799 9794688 complement(2290171..2293494) 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, CydDC cysteine exporter (CydDC-E) family (TC 3.A.1.129.z). ABCISSE: ABC transporter, permease and ATP-binding protein (IM-ABC)2, DPL-family, CYD-subfamily (Cytochrome bd biogenesis and cysteine export); cytochrome bd biosynthesis ABC transporter ATPase/permease 2293494 cydDC 9794688 cydDC Arthrobacter arilaitensis Re117 cytochrome bd biosynthesis ABC transporter ATPase/permease YP_003917205.1 2290171 R 861360 CDS YP_003917206.1 308177800 9793773 complement(2293521..2294546) 1 NC_014550.1 the cytochrome bd oxidase is a widely distributed prokaryotic quinol oxidase, which performs a variety of physiological functions in vivo. It is involved in energy- transducing respiration in Escherichia coli and Bacillus species. It plays also a role in aerotolerant nitrogen fixation and protection against metal toxicity and oxidative stress in Azotobacter vinelandii; cytochrome bd oxidase subunit 2 2294546 cydB 9793773 cydB Arthrobacter arilaitensis Re117 cytochrome bd oxidase subunit 2 YP_003917206.1 2293521 R 861360 CDS YP_003917207.1 308177801 9793772 complement(2294572..2296164) 1 NC_014550.1 the cytochrome bd oxidase is a widely distributed prokaryotic quinol oxidase, which performs a variety of physiological functions in vivo. It is involved in energy- transducing respiration in Escherichia coli and Bacillus species. It plays also a role in aerotolerant nitrogen fixation and protection against metal toxicity and oxidative stress in Azotobacter vinelandii; cytochrome bd oxidase subunit 1 2296164 cydA 9793772 cydA Arthrobacter arilaitensis Re117 cytochrome bd oxidase subunit 1 YP_003917207.1 2294572 R 861360 CDS YP_003917208.1 308177802 9793771 2296561..2296932 1 NC_014550.1 identified by match to protein family PF03965: penicillinase repressor; transcriptional repressor 2296932 9793771 AARI_20180 Arthrobacter arilaitensis Re117 transcriptional repressor YP_003917208.1 2296561 D 861360 CDS YP_003917209.1 308177803 9794689 2296956..2297918 1 NC_014550.1 match to protein family PF05569. production of beta- Lactamase and penicillin-binding protein 2a (which mediate staphylococcal resistance to beta-lactam antibiotics) is regulated by a signal-transducing integral membrane protein and a transcriptional repressor. The signal transducer is a fusion protein with penicillin-binding and zinc metalloprotease domains. The signal for protein expression is transmitted by site-specific proteolytic cleavage of both the transducer, which auto-activates, and the repressor, which is inactivated, unblocking gene transcription; M56 family peptidase 2297918 9794689 AARI_20190 Arthrobacter arilaitensis Re117 M56 family peptidase YP_003917209.1 2296956 D 861360 CDS YP_003917210.1 308177804 9794690 complement(2297989..2300097) 1 NC_014550.1 DNA gyrase negatively supercoils closed circular double-stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings. Made up of two chains. The A chain is responsible for DNA breakage and rejoining; the B chain catalyzes ATP hydrolysis; DNA gyrase subunit B 2300097 gyrB 9794690 gyrB Arthrobacter arilaitensis Re117 DNA gyrase subunit B YP_003917210.1 2297989 R 861360 CDS YP_003917211.1 308177805 9793945 2300319..2300543 1 NC_014550.1 hypothetical protein 2300543 9793945 AARI_20210 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917211.1 2300319 D 861360 CDS YP_003917212.1 308177806 9794691 complement(2300673..2301884) 1 NC_014550.1 RpoD is a primary sigma factor and directs the transcription of a wide variety of genes. Match to protein family TIGR02393; RNA polymerase sigma factor RpoD 2301884 rpoD 9794691 rpoD Arthrobacter arilaitensis Re117 RNA polymerase sigma factor RpoD YP_003917212.1 2300673 R 861360 CDS YP_003917213.1 308177807 9794345 complement(2302140..2303243) 1 NC_014550.1 hypothetical protein 2303243 9794345 AARI_20230 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917213.1 2302140 R 861360 CDS YP_003917214.1 308177808 9794692 complement(2303330..2304592) 1 NC_014550.1 major facilitator superfamily (TC 2.A.1.y.z). Identified by match to protein family PF07690 (Major Facilitator Superfamily); MFS superfamily transporter 2304592 9794692 AARI_20240 Arthrobacter arilaitensis Re117 MFS superfamily transporter YP_003917214.1 2303330 R 861360 CDS YP_003917215.1 308177809 9794693 complement(2304589..2305551) 1 NC_014550.1 hypothetical protein 2305551 9794693 AARI_20250 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917215.1 2304589 R 861360 CDS YP_003917216.1 308177810 9794694 2305808..2307322 1 NC_014550.1 selectively releases N-terminal amino acid residues from polypeptides and proteins. It is in general involved in the processing, catabolism and degradation of intracellular proteins; leucyl aminopeptidase 2307322 pepA 9794694 pepA Arthrobacter arilaitensis Re117 leucyl aminopeptidase YP_003917216.1 2305808 D 861360 CDS YP_003917217.1 308177811 9794192 2307607..2308986 1 NC_014550.1 E3 component of pyruvate dehydrogenase and 2- oxoglutarate dehydrogenase complexes; dihydrolipoyl dehydrogenase 2308986 lpdA 9794192 lpdA Arthrobacter arilaitensis Re117 dihydrolipoyl dehydrogenase YP_003917217.1 2307607 D 861360 CDS YP_003917218.1 308177812 9794044 2309105..2310745 1 NC_014550.1 it is a component of the multienzyme 2-oxoglutarate dehydrogenase complex, which is involved in the TCA cycle; dihydrolipoyllysine-residue succinyltransferase 2310745 sucB 9794044 sucB Arthrobacter arilaitensis Re117 dihydrolipoyllysine-residue succinyltransferase YP_003917218.1 2309105 D 861360 CDS YP_003917219.1 308177813 9794410 2310857..2311207 1 NC_014550.1 4 transmembranes helices predicted by TMHMM2.0; hypothetical protein 2311207 9794410 AARI_20290 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917219.1 2310857 D 861360 CDS YP_003917220.1 308177814 9794696 2312723..2314030 1 NC_014550.1 transposase of ISAar19, ISL3 family 2314030 9794696 AARI_35390 Arthrobacter arilaitensis Re117 transposase of ISAar19, ISL3 family YP_003917220.1 2312723 D 861360 CDS YP_003917221.1 308177815 9793480 2314359..2315006 1 NC_014550.1 first committed step in the biosynthesis of lipoyl cofactor. The lipoyl cofactor is essential for the function of several key enzymes involved in oxidative metabolism; lipoyl(octanoyl) transferase 2315006 lipB 9793480 lipB Arthrobacter arilaitensis Re117 lipoyl(octanoyl) transferase YP_003917221.1 2314359 D 861360 CDS YP_003917222.1 308177816 9794040 2315040..2316038 1 NC_014550.1 catalyzes the final step in the de-novo biosynthesis of the lipoyl cofactor, with the other enzyme involved being EC 2.3.1.181; lipoyl synthase 2316038 lipA 9794040 lipA Arthrobacter arilaitensis Re117 lipoyl synthase YP_003917222.1 2315040 D 861360 CDS YP_003917223.1 308177817 9794039 2316209..2316958 1 NC_014550.1 2 transmembrane helices predicted by TMHMM2.0; hypothetical protein 2316958 9794039 AARI_20330 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917223.1 2316209 D 861360 CDS YP_003917224.1 308177818 9794697 complement(2317028..2317465) 1 NC_014550.1 match to PF06271; RDD domain-containing protein 2317465 9794697 AARI_20340 Arthrobacter arilaitensis Re117 RDD domain-containing protein YP_003917224.1 2317028 R 861360 CDS YP_003917225.1 308177819 9794698 2317740..2319164 1 NC_014550.1 plays an essential role in the metabolism of nitrogen by catalyzing the condensation of glutamate and ammonia to form glutamine. The activity of class I glutamate--ammonia ligase is controlled by the adenylation of a tyrosine residue. The adenylated enzyme is inactive; glutamate--ammonia ligase, type I 2319164 glnA 9794698 glnA Arthrobacter arilaitensis Re117 glutamate--ammonia ligase, type I YP_003917225.1 2317740 D 861360 CDS YP_003917226.1 308177820 9793906 complement(2319179..2320294) 1 NC_014550.1 match to protein family PF00589; phage integrase 2320294 9793906 AARI_20360 Arthrobacter arilaitensis Re117 phage integrase YP_003917226.1 2319179 R 861360 CDS YP_003917227.1 308177821 9794699 complement(2320291..2320737) 1 NC_014550.1 match to PF01381. This is large family of DNA binding helix-turn helix proteins that include a bacterial plasmid copy control protein, bacterial methylases, various bacteriophage transcription control proteins and a vegetative specific protein from Dictyostelium discoideum (Slime mould); hypothetical protein 2320737 9794699 AARI_20370 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917227.1 2320291 R 861360 CDS YP_003917228.1 308177822 9794701 2321033..2321650 1 NC_014550.1 hypothetical protein 2321650 9794701 AARI_20390 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917228.1 2321033 D 861360 CDS YP_003917229.1 308177823 9794702 2321643..2321759 1 NC_014550.1 hypothetical protein 2321759 9794702 AARI_20400 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917229.1 2321643 D 861360 CDS YP_003917230.1 308177824 9794703 2321788..2321976 1 NC_014550.1 hypothetical protein 2321976 9794703 AARI_20410 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917230.1 2321788 D 861360 CDS YP_003917231.1 308177825 9794704 2322021..2322920 1 NC_014550.1 hypothetical protein 2322920 9794704 AARI_20420 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917231.1 2322021 D 861360 CDS YP_003917232.1 308177826 9794705 2322917..2323057 1 NC_014550.1 hypothetical protein 2323057 9794705 AARI_20430 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917232.1 2322917 D 861360 CDS YP_003917233.1 308177827 9794706 2323063..2323242 1 NC_014550.1 hypothetical protein 2323242 9794706 AARI_20440 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917233.1 2323063 D 861360 CDS YP_003917234.1 308177828 9794707 2323242..2323559 1 NC_014550.1 hypothetical protein 2323559 9794707 AARI_20450 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917234.1 2323242 D 861360 CDS YP_003917235.1 308177829 9794708 2323564..2323749 1 NC_014550.1 hypothetical protein 2323749 9794708 AARI_20460 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917235.1 2323564 D 861360 CDS YP_003917236.1 308177830 9794709 2323761..2324711 1 NC_014550.1 hypothetical protein 2324711 9794709 AARI_20470 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917236.1 2323761 D 861360 CDS YP_003917237.1 308177831 9794710 2324766..2325092 1 NC_014550.1 transposase of ISAar26, IS3 family, IS3 group, orfA 2325092 9794710 AARI_35400 Arthrobacter arilaitensis Re117 transposase of ISAar26, IS3 family, IS3 group, orfA YP_003917237.1 2324766 D 861360 CDS YP_003917238.1 308177832 9793481 2325092..2326000 1 NC_014550.1 Transposase of ISAar26, IS3 family, IS3 group, orfB 2326000 9793481 AARI_35410 Arthrobacter arilaitensis Re117 Transposase of ISAar26, IS3 family, IS3 group, orfB YP_003917238.1 2325092 D 861360 CDS YP_003917239.1 308177833 9793482 2326418..2326834 1 NC_014550.1 hypothetical protein 2326834 9793482 AARI_20480 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917239.1 2326418 D 861360 CDS YP_003917240.1 308177834 9794711 complement(2326896..2327495) 1 NC_014550.1 signal peptide predicted by SignalP 3.0 HMM (probability: 1.000) with cleavage site probability 0.536 between position 40 and 41; hypothetical protein 2327495 9794711 AARI_20490 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917240.1 2326896 R 861360 CDS YP_003917241.1 308177835 9794712 complement(2327553..2327771) 1 NC_014550.1 similar to protein Gp28 (SP:Q855T5; Mycobacterium phage Che9d); hypothetical protein 2327771 9794712 AARI_20500 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917241.1 2327553 R 861360 CDS YP_003917242.1 308177836 9794713 complement(2327768..2327914) 1 NC_014550.1 hypothetical protein 2327914 9794713 AARI_20510 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917242.1 2327768 R 861360 CDS YP_003917243.1 308177837 9794714 complement(2328216..2328701) 1 NC_014550.1 signal peptide predicted by SignalP 3.0 HMM (probability: 0.991) with cleavage site probability 0.664 between position 32 and 33; hypothetical protein 2328701 9794714 AARI_20520 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917243.1 2328216 R 861360 CDS YP_003917244.1 308177838 9794715 complement(2328789..2329007) 1 NC_014550.1 similar to protein Gp28 (SP:Q855T5; Mycobacterium phage Che9d); hypothetical protein 2329007 9794715 AARI_20530 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917244.1 2328789 R 861360 CDS YP_003917245.1 308177839 9794716 2329518..2329676 1 NC_014550.1 hypothetical protein 2329676 9794716 AARI_20540 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917245.1 2329518 D 861360 CDS YP_003917246.1 308177840 9794717 complement(2329985..2330455) 1 NC_014550.1 nucleoside deaminase-like protein 2330455 9794717 AARI_20550 Arthrobacter arilaitensis Re117 nucleoside deaminase-like protein YP_003917246.1 2329985 R 861360 CDS YP_003917247.1 308177841 9794718 complement(2330562..2331044) 1 NC_014550.1 hypothetical protein 2331044 9794718 AARI_20560 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917247.1 2330562 R 861360 CDS YP_003917248.1 308177842 9794719 complement(2331053..2334079) 1 NC_014550.1 regulates the activity of glutamate--ammonia ligase by attachment of the adenylyl moiety of ATP; [Glutamate--ammonia ligase] adenylyltransferase 2334079 glnE 9794719 glnE Arthrobacter arilaitensis Re117 [Glutamate--ammonia ligase] adenylyltransferase YP_003917248.1 2331053 R 861360 CDS YP_003917249.1 308177843 9793908 complement(2334132..2335472) 1 NC_014550.1 plays an essential role in the metabolism of nitrogen by catalyzing the condensation of glutamate and ammonia to form glutamine. The activity of class I glutamate--ammonia ligase is controlled by the adenylation of a tyrosine residue. The adenylated enzyme is inactive; glutamate--ammonia ligase, type I 2335472 glnA 9793908 glnA Arthrobacter arilaitensis Re117 glutamate--ammonia ligase, type I YP_003917249.1 2334132 R 861360 CDS YP_003917250.1 308177844 9793907 2335609..2336445 1 NC_014550.1 catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate: 5,10-methylenetetrahydrofolate + 3-methyl-2- oxobutanoate + H2O = tetrahydrofolate + 2-dehydropantoate; 3-methyl-2-oxobutanoate hydroxymethyltransferase 2336445 panB 9793907 panB Arthrobacter arilaitensis Re117 3-methyl-2-oxobutanoate hydroxymethyltransferase YP_003917250.1 2335609 D 861360 CDS YP_003917251.1 308177845 9794173 complement(2336555..2336749) 1 NC_014550.1 hypothetical protein 2336749 9794173 AARI_20600 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917251.1 2336555 R 861360 CDS YP_003917252.1 308177846 9794720 2336884..2337759 1 NC_014550.1 responsible for the removal of the amino-terminal (initiator) methionine from nascent eukaryotic cytosolic and cytoplasmic prokaryotic proteins if the penultimate amino acid is small and uncharged; methionyl aminopeptidase 2337759 map 9794720 map Arthrobacter arilaitensis Re117 methionyl aminopeptidase YP_003917252.1 2336884 D 861360 CDS YP_003917253.1 308177847 9794059 complement(2337837..2338325) 1 NC_014550.1 transcriptional regulator 2338325 9794059 AARI_20620 Arthrobacter arilaitensis Re117 transcriptional regulator YP_003917253.1 2337837 R 861360 CDS YP_003917254.1 308177848 9794721 complement(2338410..2339762) 1 NC_014550.1 catalyzes the terminal step in the biosynthesis of histidine, the four-electron oxidation of L-histidinol to histidine; histidinol dehydrogenase 2339762 hisD 9794721 hisD Arthrobacter arilaitensis Re117 histidinol dehydrogenase YP_003917254.1 2338410 R 861360 CDS YP_003917255.1 308177849 9793963 complement(2339840..2343349) 1 NC_014550.1 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The beta chain is required for initiation of replication once it is clamped onto DNA. DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII complex. PolIII associates with the gamma complex (composed of gamma, delta, delta prime, psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex; DNA polymerase III subunit alpha 2343349 dnaE 9793963 dnaE Arthrobacter arilaitensis Re117 DNA polymerase III subunit alpha YP_003917255.1 2339840 R 861360 CDS YP_003917256.1 308177850 9793823 complement(2343509..2344453) 1 NC_014550.1 identified by match to protein family PF00849. Pseudouridylate synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5- ribosyluracil, psi); pseudouridylate synthase 2344453 9793823 AARI_20650 Arthrobacter arilaitensis Re117 pseudouridylate synthase YP_003917256.1 2343509 R 861360 CDS YP_003917257.1 308177851 9794722 complement(2344450..2345031) 1 NC_014550.1 releases signal peptides from bacterial membrane prolipoproteins; signal peptidase II 2345031 lspA 9794722 lspA Arthrobacter arilaitensis Re117 signal peptidase II YP_003917257.1 2344450 R 861360 CDS YP_003917258.1 308177852 9794047 complement(2345129..2345878) 1 NC_014550.1 match to PF05103; DivIVA family protein 2345878 9794047 AARI_20670 Arthrobacter arilaitensis Re117 DivIVA family protein YP_003917258.1 2345129 R 861360 CDS YP_003917259.1 308177853 9794723 complement(2346108..2346404) 1 NC_014550.1 3 transmembrane helices predicted by TMHMM2.0; hypothetical protein 2346404 9794723 AARI_20680 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917259.1 2346108 R 861360 CDS YP_003917260.1 308177854 9794724 complement(2346428..2346979) 1 NC_014550.1 hypothetical protein 2346979 9794724 AARI_20690 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917260.1 2346428 R 861360 CDS YP_003917261.1 308177855 9794725 complement(2347077..2347826) 1 NC_014550.1 hypothetical protein 2347826 9794725 AARI_20700 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917261.1 2347077 R 861360 CDS YP_003917262.1 308177856 9794726 complement(2347847..2349037) 1 NC_014550.1 FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes. It is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. It forms a ring-shaped septum at the site of bacterial cell division, which is required for constriction of cell membrane and cell envelope to yield two daughter cells; cell division protein FtsZ 2349037 ftsZ 9794726 ftsZ Arthrobacter arilaitensis Re117 cell division protein FtsZ YP_003917262.1 2347847 R 861360 CDS YP_003917263.1 308177857 9793871 complement(2349256..2349990) 1 NC_014550.1 match to PF08478: POTRA domain, FtsQ-type. The POTRA domain (for polypeptide-transport-associated domain) is found in different types of proteins, usually associated with a transmembrane beta-barrel; POTRA domain-containing protein 2349990 9793871 AARI_20720 Arthrobacter arilaitensis Re117 POTRA domain-containing protein YP_003917263.1 2349256 R 861360 CDS YP_003917264.1 308177858 9794727 complement(2350053..2351450) 1 NC_014550.1 involved in peptidoglycan biosynthesis; UDP-N-acetylmuramate--L-alanine ligase 2351450 murC 9794727 murC Arthrobacter arilaitensis Re117 UDP-N-acetylmuramate--L-alanine ligase YP_003917264.1 2350053 R 861360 CDS YP_003917265.1 308177859 9794118 complement(2351455..2352576) 1 NC_014550.1 catalyzes the following reaction: UDP-N- acetylglucosamine + Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D- Ala-D-Ala)- diphosphoundecaprenol <=> UDP + GlcNAc-(1->4)- Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D- Ala)- diphosphoundecaprenol. Involved in peptidoglycan biosynthesis; undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase 2352576 murG 9794118 murG Arthrobacter arilaitensis Re117 undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase YP_003917265.1 2351455 R 861360 CDS YP_003917266.1 308177860 9794122 complement(2352677..2353930) 1 NC_014550.1 plays a role in the stabilization of the FtsZ ring during cell division; cell division protein FtsW 2353930 ftsW 9794122 ftsW Arthrobacter arilaitensis Re117 cell division protein FtsW YP_003917266.1 2352677 R 861360 CDS YP_003917267.1 308177861 9793868 complement(2353974..2355503) 1 NC_014550.1 involved in peptidoglycan biosynthesis; UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase 2355503 murD 9793868 murD Arthrobacter arilaitensis Re117 UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase YP_003917267.1 2353974 R 861360 CDS YP_003917268.1 308177862 9794119 complement(2355500..2356603) 1 NC_014550.1 catalyzes the formation of undecaprenyl- pyrophosphoryl-N-acetylmuramoyl-pentapeptide from UDP- MurNAc-pentapeptide and undecaprenyl-phosphate. Involved in peptidoglycan biosynthesis; phospho-N-acetylmuramoyl-pentapeptide- transferase 2356603 mraY 9794119 mraY Arthrobacter arilaitensis Re117 phospho-N-acetylmuramoyl-pentapeptide- transferase YP_003917268.1 2355500 R 861360 CDS YP_003917269.1 308177863 9794106 complement(2356600..2358057) 1 NC_014550.1 involved in peptidoglycan biosynthesis: ATP + UDP-N- acetylmuramoyl-L-alanyl-gamma-D-glutamyl-L-lysine + D- alanyl-D-alanine => ADP + phosphate + UDP-N-acetylmuramoyl- L-alanyl-gamma-D-glutamyl-L-lysyl-D- alanyl-D-alanine. Also catalyzes the reaction when the C-terminal residue of the tripeptide is meso-2, 4-diaminoheptanedioate (acylated at its L-center); UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase 2358057 murF 9794106 murF Arthrobacter arilaitensis Re117 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase YP_003917269.1 2356600 R 861360 CDS YP_003917270.1 308177864 9794121 complement(2358108..2359700) 1 NC_014550.1 catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D- glutamate (UMAG) in the biosynthesis of bacterial cell- wall peptidoglycan. Corresponds probably to EC 6.3.2.7 rather than 6.3.2.13, as the cell-wall peptidoglycan type of Arthrobacter arilaitensis is Lys-Glu (variation A4alpha); UDP-N-acetylmuramyl-tripeptide synthetase 2359700 murE 9794121 murE Arthrobacter arilaitensis Re117 UDP-N-acetylmuramyl-tripeptide synthetase YP_003917270.1 2358108 R 861360 CDS YP_003917271.1 308177865 9794120 complement(2359694..2361472) 1 NC_014550.1 match to PF00905. The large number of penicillin binding proteins, which are represented in this group of sequences, are responsible for the final stages of peptidoglycan biosynthesis for cell wall formation. The proteins synthesise cross-linked peptidoglycan from lipid intermediates, and contain a penicillin-sensitive transpeptidase carboxy-terminal domain; penicillin-binding protein 2361472 9794120 AARI_20800 Arthrobacter arilaitensis Re117 penicillin-binding protein YP_003917271.1 2359694 R 861360 CDS YP_003917272.1 308177866 9794728 complement(2361583..2362353) 1 NC_014550.1 1 transmembrane helice predicted by TMHMM2.0; hypothetical protein 2362353 9794728 AARI_20810 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917272.1 2361583 R 861360 CDS YP_003917273.1 308177867 9794729 complement(2362355..2363347) 1 NC_014550.1 S-adenosyl-L-methionine-dependent methyltransferase MraW 2363347 mraW 9794729 mraW Arthrobacter arilaitensis Re117 S-adenosyl-L-methionine-dependent methyltransferase MraW YP_003917273.1 2362355 R 861360 CDS YP_003917274.1 308177868 9794105 complement(2363519..2363932) 1 NC_014550.1 this protein often is found with other genes of the dcw (division cell wall) gene cluster, including mraW, ftsI, murE, murF, ftsW, murG, etc.; MraZ protein 2363932 mraZ 9794105 mraZ Arthrobacter arilaitensis Re117 MraZ protein YP_003917274.1 2363519 R 861360 CDS YP_003917275.1 308177869 9794107 complement(2364450..2364833) 1 NC_014550.1 2 transmembrane helices predicted by TMHMM2.0; hypothetical protein 2364833 9794107 AARI_20840 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917275.1 2364450 R 861360 CDS YP_003917276.1 308177870 9794730 complement(2365016..2366182) 1 NC_014550.1 DNA polymerase IV is involved in DNA repair; DNA polymerase IV 2366182 dinB 9794730 dinB Arthrobacter arilaitensis Re117 DNA polymerase IV YP_003917276.1 2365016 R 861360 CDS YP_003917277.1 308177871 9793814 2366345..2367451 1 NC_014550.1 identified by similarity to protein SP:Q9KK76 (Brevibacterium linens). A variety of isoprenoid compounds are synthesized by various organisms. In bacteria this pathway leads to the synthesis of isopentenyl tRNA, isoprenoid quinones, and sugar carrier lipids. Farnesyltranstransferase catalyzes the sequential addition of the three molecules of isopentenyl pyrophosphate onto dimethylallyl pyrophosphate to form geranylgeranyl pyrophosphate; farnesyltranstransferase 2367451 crtE 9793814 crtE Arthrobacter arilaitensis Re117 farnesyltranstransferase YP_003917277.1 2366345 D 861360 CDS YP_003917278.1 308177872 9793759 complement(2367552..2367905) 1 NC_014550.1 hypothetical protein 2367905 9793759 AARI_20870 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917278.1 2367552 R 861360 CDS YP_003917279.1 308177873 9794731 2368112..2369812 1 NC_014550.1 match to protein domain PF01476. This domain is about 40 residues long and is found in a variety of enzymes involved in bacterial cell wall degradation. It may have a general peptidoglycan binding function; LysM domain-containing protein 2369812 9794731 AARI_20880 Arthrobacter arilaitensis Re117 LysM domain-containing protein YP_003917279.1 2368112 D 861360 CDS YP_003917280.1 308177874 9794732 complement(2369888..2371375) 1 NC_014550.1 protein-histidine kinases are key elements in two- component signal transduction systems, which enable bacteria to sense, respond, and adapt to a wide range of environments, stressors, and growth conditions; signal transduction histidine kinase 2371375 9794732 AARI_20890 Arthrobacter arilaitensis Re117 signal transduction histidine kinase YP_003917280.1 2369888 R 861360 CDS YP_003917281.1 308177875 9794733 complement(2371385..2376178) 1 NC_014550.1 catalyzes the NAD-dependent reversible oxidative deamination of glutamate to 2-oxoglutarate and ammonia; NAD-specific glutamate dehydrogenase 2376178 gdh 9794733 gdh Arthrobacter arilaitensis Re117 NAD-specific glutamate dehydrogenase YP_003917281.1 2371385 R 861360 CDS YP_003917282.1 308177876 9793895 complement(2376304..2377551) 1 NC_014550.1 hypothetical protein 2377551 9793895 AARI_20910 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917282.1 2376304 R 861360 CDS YP_003917283.1 308177877 9794734 complement(2377548..2378213) 1 NC_014550.1 1 transmembrane helice predicted by TMHMM2.0; hypothetical protein 2378213 9794734 AARI_20920 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917283.1 2377548 R 861360 CDS YP_003917284.1 308177878 9794735 complement(2378304..2378864) 1 NC_014550.1 hypothetical protein 2378864 9794735 AARI_20930 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917284.1 2378304 R 861360 CDS YP_003917285.1 308177879 9794736 2378987..2379709 1 NC_014550.1 2 transmembrane helices predicted by TMHMM2.0; hypothetical protein 2379709 9794736 AARI_20940 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917285.1 2378987 D 861360 CDS YP_003917286.1 308177880 9794737 2379753..2380274 1 NC_014550.1 hypothetical protein 2380274 9794737 AARI_20950 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917286.1 2379753 D 861360 CDS YP_003917287.1 308177881 9794738 complement(2380271..2382916) 1 NC_014550.1 the translocase itself comprises 7 proteins, including a chaperone protein (SecB), an ATPase (SecA), an integral membrane complex (SecCY, SecE and SecG), and two additional membrane proteins that promote the release of the mature peptide into the periplasm (SecD and SecF); preprotein translocase subunit SecA 2382916 secA 9794738 secA Arthrobacter arilaitensis Re117 preprotein translocase subunit SecA YP_003917287.1 2380271 R 861360 CDS YP_003917288.1 308177882 9794386 complement(2383050..2384222) 1 NC_014550.1 hypothetical protein 2384222 9794386 AARI_20970 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917288.1 2383050 R 861360 CDS YP_003917289.1 308177883 9794739 complement(2384246..2384944) 1 NC_014550.1 match to protein family PF02482; ribosome-associated protein 2384944 9794739 AARI_20980 Arthrobacter arilaitensis Re117 ribosome-associated protein YP_003917289.1 2384246 R 861360 CDS YP_003917290.1 308177884 9794740 complement(2385114..2385902) 1 NC_014550.1 match to protein domain PF00156. This family includes a range of diverse phosphoribosyl transferase enzymes; phosphoribosyl transferase 2385902 9794740 AARI_20990 Arthrobacter arilaitensis Re117 phosphoribosyl transferase YP_003917290.1 2385114 R 861360 CDS YP_003917291.1 308177885 9794741 complement(2385972..2387675) 1 NC_014550.1 possible role in the MtrAB signal transduction pathway; lipoprotein LpqB 2387675 lpqB 9794741 lpqB Arthrobacter arilaitensis Re117 lipoprotein LpqB YP_003917291.1 2385972 R 861360 CDS YP_003917292.1 308177886 9794046 complement(2387675..2389495) 1 NC_014550.1 member of the two-component regulatory system mtrA/mtrB. Seems to function as a membrane-associated protein kinase that phosphorylates MtrA in response to environmental signals; sensor histidine kinase MtrB 2389495 mtrB 9794046 mtrB Arthrobacter arilaitensis Re117 sensor histidine kinase MtrB YP_003917292.1 2387675 R 861360 CDS YP_003917293.1 308177887 9794115 complement(2389492..2390172) 1 NC_014550.1 member of the two-component regulatory system mtrA/mtrB; DNA-binding response regulator MtrA 2390172 mtrA 9794115 mtrA Arthrobacter arilaitensis Re117 DNA-binding response regulator MtrA YP_003917293.1 2389492 R 861360 CDS YP_003917294.1 308177888 9794114 complement(2390308..2391372) 1 NC_014550.1 hypothetical protein 2391372 9794114 AARI_21030 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917294.1 2390308 R 861360 CDS YP_003917295.1 308177889 9794742 complement(2391365..2391736) 1 NC_014550.1 catalyzes the Claisen rearrangement of chorismate to prephenate, which can subsequently be converted to precursors of either phenylalanine or tyrosine; chorismate mutase 2391736 aroH 9794742 aroH Arthrobacter arilaitensis Re117 chorismate mutase YP_003917295.1 2391365 R 861360 CDS YP_003917296.1 308177890 9793687 complement(2391848..2393539) 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, peptide/opine/nickel uptake transporter (PepT) family (TC 3.A.1.5.z). ABCISSE: ABC transporter, fused ATP-binding protein (ABC2), OPN-family (oligopeptides and nickel), oligopeptides import; dipeptide/oligopeptide ABC transporter ATP-binding subunit 2393539 9793687 AARI_21050 Arthrobacter arilaitensis Re117 dipeptide/oligopeptide ABC transporter ATP-binding subunit YP_003917296.1 2391848 R 861360 CDS YP_003917297.1 308177891 9794743 complement(2393536..2394522) 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, peptide/opine/nickel uptake transporter (PepT) family (TC 3.A.1.5.z). ABCISSE: ABC transporter, permease (IM), OPN- family (oligopeptides and nickel), oligopeptides import; dipeptide/oligopeptide ABC transporter inner membrane subunit 2394522 9794743 AARI_21060 Arthrobacter arilaitensis Re117 dipeptide/oligopeptide ABC transporter inner membrane subunit YP_003917297.1 2393536 R 861360 CDS YP_003917298.1 308177892 9794744 complement(2394525..2395616) 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, peptide/opine/nickel uptake transporter (PepT) family (TC 3.A.1.5.z). ABCISSE: ABC transporter, permease (IM), OPN- family (oligopeptides and nickel), oligopeptides import; dipeptide/oligopeptide ABC transporter inner membrane subunit 2395616 9794744 AARI_21070 Arthrobacter arilaitensis Re117 dipeptide/oligopeptide ABC transporter inner membrane subunit YP_003917298.1 2394525 R 861360 CDS YP_003917299.1 308177893 9794745 complement(2395763..2397397) 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, peptide/opine/nickel uptake transporter (PepT) family (TC 3.A.1.5.z). ABCISSE: ABC transporter, binding protein (BP), OPN-family (oligopeptides and nickel), oligopeptides import; dipeptide/oligopeptide ABC transporter substrate-binding protein 2397397 9794745 AARI_21080 Arthrobacter arilaitensis Re117 dipeptide/oligopeptide ABC transporter substrate-binding protein YP_003917299.1 2395763 R 861360 CDS YP_003917300.1 308177894 9794746 2397626..2397985 1 NC_014550.1 hypothetical protein 2397985 9794746 AARI_21090 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917300.1 2397626 D 861360 CDS YP_003917301.1 308177895 9794747 complement(2398074..2400779) 1 NC_014550.1 13 transmembrane helices predicted by TMHMM2.0. Match to protein domain PF07732: multicopper oxidase; hypothetical protein 2400779 9794747 AARI_21100 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917301.1 2398074 R 861360 CDS YP_003917302.1 308177896 9794748 complement(2400772..2401902) 1 NC_014550.1 10 transmembrane helices predicted by TMHMM2.0; hypothetical protein 2401902 9794748 AARI_21110 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917302.1 2400772 R 861360 CDS YP_003917303.1 308177897 9794749 complement(2401899..2402579) 1 NC_014550.1 transcriptional regulator 2402579 9794749 AARI_21120 Arthrobacter arilaitensis Re117 transcriptional regulator YP_003917303.1 2401899 R 861360 CDS YP_003917304.1 308177898 9794750 2402716..2403033 1 NC_014550.1 hypothetical protein 2403033 9794750 AARI_21130 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917304.1 2402716 D 861360 CDS YP_003917305.1 308177899 9794751 complement(2403092..2404228) 1 NC_014550.1 catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34; tRNA-specific 2-thiouridylase MnmA 2404228 mnmA 9794751 mnmA Arthrobacter arilaitensis Re117 tRNA-specific 2-thiouridylase MnmA YP_003917305.1 2403092 R 861360 CDS YP_003917306.1 308177900 9794090 complement(2404225..2405460) 1 NC_014550.1 identified by match to protein family PIRSF005572: cysteine desulfurase, NifS type. Cysteine desulfurase catalyses the following reaction: L-cysteine + [enzyme]- cysteine <=> L-alanine + [enzyme]-S-sulfanylcysteine. It is involved in the biosynthesis of iron-sulfur clusters, thio-nucleosides in tRNA, thiamine, biotin, lipoate and pyranopterin (molybdopterin) and functions by mobilizing sulfur; cysteine desulfurase 2405460 9794090 AARI_21150 Arthrobacter arilaitensis Re117 cysteine desulfurase YP_003917306.1 2404225 R 861360 CDS YP_003917307.1 308177901 9794752 complement(2405490..2406299) 1 NC_014550.1 signal peptide predicted by SignalP 3.0 HMM (probability: 0.912) with cleavage site probability 0.909 between position 28 and 29; hypothetical protein 2406299 9794752 AARI_21160 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917307.1 2405490 R 861360 CDS YP_003917308.1 308177902 9794753 2406412..2407338 1 NC_014550.1 catalyzes the condensation of 6-hydroxymethyl-7,8- dihydropteridine pyrophosphate to para-aminobenzoic acid to form 7,8-dihydropteroate. This is the second step in the three steps pathway leading from 6-hydroxymethyl-7,8- dihydropterin to 7,8-dihydrofolate. It is the target of sulfonamides which are substrates analog that compete with para-aminobenzoic acid; dihydropteroate synthase 2407338 9794753 AARI_21170 Arthrobacter arilaitensis Re117 dihydropteroate synthase YP_003917308.1 2406412 D 861360 CDS YP_003917309.1 308177903 9794754 2407352..2408110 1 NC_014550.1 match to protein domain PF01872. This domain is found in the C-terminus of the bifunctional deaminase- reductase in combination with PF00383 as well as in isolation in some archaebacterial proteins; RibD domain-containing protein 2408110 9794754 AARI_21180 Arthrobacter arilaitensis Re117 RibD domain-containing protein YP_003917309.1 2407352 D 861360 CDS YP_003917310.1 308177904 9794755 complement(2408079..2408978) 1 NC_014550.1 match to protein domain PF00781; diacylglycerol kinase catalytic domain-containing protein 2408978 9794755 AARI_21190 Arthrobacter arilaitensis Re117 diacylglycerol kinase catalytic domain-containing protein YP_003917310.1 2408079 R 861360 CDS YP_003917311.1 308177905 9794756 2409095..2409994 1 NC_014550.1 match to protein domain PF0026; DnaJ domain-containing protein 2409994 9794756 AARI_21200 Arthrobacter arilaitensis Re117 DnaJ domain-containing protein YP_003917311.1 2409095 D 861360 CDS YP_003917312.1 308177906 9794757 2410039..2410500 1 NC_014550.1 identified by match to protein family PF00588: SpoU rRNA Methylase family. Possible role in rRNA modification; RNA methyltransferase 2410500 9794757 AARI_21210 Arthrobacter arilaitensis Re117 RNA methyltransferase YP_003917312.1 2410039 D 861360 CDS YP_003917313.1 308177907 9794758 2410624..2411181 1 NC_014550.1 1 transmembrane helice predicted by TMHMM2.0; hypothetical protein 2411181 9794758 AARI_21220 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917313.1 2410624 D 861360 CDS YP_003917314.1 308177908 9794759 complement(2411274..2412035) 1 NC_014550.1 LmbE family protein 2412035 9794759 AARI_21230 Arthrobacter arilaitensis Re117 LmbE family protein YP_003917314.1 2411274 R 861360 CDS YP_003917315.1 308177909 9794760 complement(2412032..2412976) 1 NC_014550.1 identified by match to PIRSF000089. Electron transfer flavoproteins (ETFs) serve as specific electron acceptors for primary dehydrogenases, transferring the electrons to terminal respiratory systems. They can be functionally classified into constitutive, (housekeeping) ETFs, mainly involved in the oxidation of fatty acids (Group I), and ETFs produced by some prokaryotes under specific growth conditions, receiving electrons only from the oxidation of specific substrates (Group II). They consist of three domains: domains I and II are formed by the N- and C-terminal portions of the alpha subunit, respectively, while domain III is formed by the beta subunit; electron transfer flavoprotein subunit alpha 2412976 fixB 9794760 fixB Arthrobacter arilaitensis Re117 electron transfer flavoprotein subunit alpha YP_003917315.1 2412032 R 861360 CDS YP_003917316.1 308177910 9793853 complement(2412989..2413810) 1 NC_014550.1 electron transfer flavoproteins (ETFs) serve as specific electron acceptors for primary dehydrogenases, transferring the electrons to terminal respiratory systems. They can be functionally classified into constitutive, (housekeeping) ETFs, mainly involved in the oxidation of fatty acids (Group I), and ETFs produced by some prokaryotes under specific growth conditions, receiving electrons only from the oxidation of specific substrates (Group II). They consist of three domains: domains I and II are formed by the N- and C-terminal portions of the alpha subunit, respectively, while domain III is formed by the beta subunit; electron transfer flavoprotein subunit beta 2413810 fixA 9793853 fixA Arthrobacter arilaitensis Re117 electron transfer flavoprotein subunit beta YP_003917316.1 2412989 R 861360 CDS YP_003917317.1 308177911 9793851 complement(2414001..2415491) 1 NC_014550.1 1 transmembrane helice predicted by TMHMM2.0; serine protease 2415491 9793851 AARI_21260 Arthrobacter arilaitensis Re117 serine protease YP_003917317.1 2414001 R 861360 CDS YP_003917318.1 308177912 9794761 2415733..2417805 1 NC_014550.1 signal peptide predicted by SignalP 3.0 HMM (probability: 1.000) with cleavage site probability 0.994 between position 28 and 29. Presence of transmembrane helices; hypothetical protein 2417805 9794761 AARI_21270 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917318.1 2415733 D 861360 CDS YP_003917319.1 308177913 9794762 2417876..2418607 1 NC_014550.1 identified by match to protein family PF04012. This family includes PspA, which is a protein that suppresses sigma54-dependent transcription; pspA/IM30 family protein 2418607 9794762 AARI_21280 Arthrobacter arilaitensis Re117 pspA/IM30 family protein YP_003917319.1 2417876 D 861360 CDS YP_003917320.1 308177914 9793637 complement(2419738..2422773) 1 NC_014550.1 identified by match to PF03699: Uncharacterised protein family (UPF0182). This family contains uncharacterised integral membrane proteins; hypothetical protein 2422773 9793637 AARI_21290 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917320.1 2419738 R 861360 CDS YP_003917321.1 308177915 9794764 complement(2422904..2424019) 1 NC_014550.1 1 transmembrane helice predicted by TMHMM2.0; hypothetical protein 2424019 9794764 AARI_21300 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917321.1 2422904 R 861360 CDS YP_003917322.1 308177916 9794765 2424203..2425642 1 NC_014550.1 hypothetical protein 2425642 9794765 AARI_21310 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917322.1 2424203 D 861360 CDS YP_003917323.1 308177917 9794766 complement(2425706..2426383) 1 NC_014550.1 hypothetical protein 2426383 9794766 AARI_21320 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917323.1 2425706 R 861360 CDS YP_003917324.1 308177918 9794767 complement(2426447..2428570) 1 NC_014550.1 match to protein family PS51198: UvrD-like DNA helicase ATP-binding domain profile and PS51217: DNA helicase, UvrD-like, C terminal. UvrD-like DNA helicases belong to superfamily 1 (SF1); ATP-dependent DNA helicase 2428570 9794767 AARI_21330 Arthrobacter arilaitensis Re117 ATP-dependent DNA helicase YP_003917324.1 2426447 R 861360 CDS YP_003917325.1 308177919 9794768 complement(2428567..2429496) 1 NC_014550.1 NAD(+) diphosphatase catalyses the following reaction: NAD(+) + H(2)O <=> AMP + NMN; NAD(+) diphosphatase 2429496 nudC 9794768 nudC Arthrobacter arilaitensis Re117 NAD(+) diphosphatase YP_003917325.1 2428567 R 861360 CDS YP_003917326.1 308177920 9794152 2429664..2430938 1 NC_014550.1 identified by match to PF01636. This family consists of bacterial antibiotic resistance proteins, which confer resistance to various aminoglycosides. It also includes homoserine kinase; aminoglycoside phosphotransferase-like protein 2430938 9794152 AARI_21350 Arthrobacter arilaitensis Re117 aminoglycoside phosphotransferase-like protein YP_003917326.1 2429664 D 861360 CDS YP_003917327.1 308177921 9794769 complement(2430962..2434279) 1 NC_014550.1 match to protein family PS51198: UvrD-like DNA helicase ATP-binding domain profile and PS51217: DNA helicase, UvrD-like, C terminal. UvrD-like DNA helicases belong to superfamily 1 (SF1); ATP-dependent DNA helicase 2434279 9794769 AARI_21360 Arthrobacter arilaitensis Re117 ATP-dependent DNA helicase YP_003917327.1 2430962 R 861360 CDS YP_003917328.1 308177922 9794770 complement(2434276..2437488) 1 NC_014550.1 match to protein family PS51198: UvrD-like DNA helicase ATP-binding domain profile and PS51217: DNA helicase, UvrD-like, C terminal. UvrD-like DNA helicases belong to superfamily 1 (SF1); ATP-dependent DNA helicase 2437488 9794770 AARI_21370 Arthrobacter arilaitensis Re117 ATP-dependent DNA helicase YP_003917328.1 2434276 R 861360 CDS YP_003917329.1 308177923 9794771 complement(2437485..2437874) 1 NC_014550.1 involved in the repair of alkylated DNA; methylated-DNA--[protein]-cysteine S-methyltransferase 2437874 9794771 AARI_21380 Arthrobacter arilaitensis Re117 methylated-DNA--[protein]-cysteine S-methyltransferase YP_003917329.1 2437485 R 861360 CDS YP_003917330.1 308177924 9794772 2437963..2438646 1 NC_014550.1 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The beta chain is required for initiation of replication once it is clamped onto DNA. DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII complex. PolIII associates with the gamma complex (composed of gamma, delta, delta, psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex; DNA polymerase III subunit epsilon 2438646 9794772 AARI_21390 Arthrobacter arilaitensis Re117 DNA polymerase III subunit epsilon YP_003917330.1 2437963 D 861360 CDS YP_003917331.1 308177925 9794773 2438893..2439885 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, methionine uptake transporter (MUT) family (TC3.A.1.24). ABCISSE: ABC transporter, ATP-binding protein (ABC), DLM- family. Part of the ABC transporter complex MetNIQ involved in methionine import. The complex is composed of two ATP-binding proteins (MetN), two transmembrane proteins (MetI) and a solute-binding protein (MetQ); methionine ABC transporter ATP-binding subunit MetN 2439885 metN 9794773 metN Arthrobacter arilaitensis Re117 methionine ABC transporter ATP-binding subunit MetN YP_003917331.1 2438893 D 861360 CDS YP_003917332.1 308177926 9794076 2439889..2440554 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, methionine uptake transporter (MUT) family (TC3.A.1.24). ABCISSE: ABC transporter, permease (IM), DLM-family. Part of the ABC transporter complex MetNIQ involved in methionine import. The complex is composed of two ATP- binding proteins (MetN), two transmembrane proteins (MetI) and a solute-binding protein (MetQ); methionine ABC transporter inner membrane subunit MetI 2440554 metI 9794076 metI Arthrobacter arilaitensis Re117 methionine ABC transporter inner membrane subunit MetI YP_003917332.1 2439889 D 861360 CDS YP_003917333.1 308177927 9794073 2440660..2441508 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, methionine uptake transporter (MUT) family (TC3.A.1.24). ABCISSE: ABC transporter, lipoprotein (LPP), DLM-family. Part of the ABC transporter complex metNIQ involved in methionine import. The complex is composed of two ATP- binding proteins (MetN), two transmembrane proteins (MetI) and a solute-binding protein (MetQ); methionine ABC transporter substrate-binding protein MetQ 2441508 metQ 9794073 metQ Arthrobacter arilaitensis Re117 methionine ABC transporter substrate-binding protein MetQ YP_003917333.1 2440660 D 861360 CDS YP_003917334.1 308177928 9794078 complement(2441685..2442992) 1 NC_014550.1 involved in the second step of porphyrin biosynthesis, via the C5 pathway by transfering the amino group on carbon 2 of glutamate-1- semialdehyde to the neighbouring carbon, to give delta-aminolevulinic acid; glutamate-1-semialdehyde 2,1-aminomutase 2442992 hemL 9794078 hemL Arthrobacter arilaitensis Re117 glutamate-1-semialdehyde 2,1-aminomutase YP_003917334.1 2441685 R 861360 CDS YP_003917335.1 308177929 9793959 complement(2442998..2443981) 1 NC_014550.1 catalyzes the second step in the biosynthesis of heme, the condensation of two molecules of 5- aminolevulinate to form porphobilinogen: 2 5- aminolevulinate <=> porphobilinogen + 2 H(2)O; porphobilinogen synthase 2443981 hemB 9793959 hemB Arthrobacter arilaitensis Re117 porphobilinogen synthase YP_003917335.1 2442998 R 861360 CDS YP_003917336.1 308177930 9793949 complement(2444044..2444835) 1 NC_014550.1 uroporphyrinogen-III synthase catalyses the following reaction: hydroxymethylbilane <=> uroporphyrinogen III + H(2)O; uroporphyrinogen-III synthase 2444835 hemD 9793949 hemD Arthrobacter arilaitensis Re117 uroporphyrinogen-III synthase YP_003917336.1 2444044 R 861360 CDS YP_003917337.1 308177931 9793951 complement(2444845..2445819) 1 NC_014550.1 involved in the biosynthesis of porphyrins and related macrocycles, catalyzes the assembly of four porphobilinogen (PBG) units in a head to tail fashion to form hydroxymethylbilane: 4 porphobilinogen + H2O <=> hydroxymethylbilane + 4 NH3; hydroxymethylbilane synthase 2445819 hemC 9793951 hemC Arthrobacter arilaitensis Re117 hydroxymethylbilane synthase YP_003917337.1 2444845 R 861360 CDS YP_003917338.1 308177932 9793950 complement(2445816..2447021) 1 NC_014550.1 catalyzes the last step in heme biosynthesis: the chelation of a ferrous ion to proto-porphyrin IX, to form protoheme: Protoheme + 2 H+ <=> protoporphyrin + Fe2+; ferrochelatase 2447021 hemH 9793950 hemH Arthrobacter arilaitensis Re117 ferrochelatase YP_003917338.1 2445816 R 861360 CDS YP_003917339.1 308177933 9793957 complement(2447018..2447737) 1 NC_014550.1 chlorite dismutase family protein 2447737 9793957 AARI_21480 Arthrobacter arilaitensis Re117 chlorite dismutase family protein YP_003917339.1 2447018 R 861360 CDS YP_003917340.1 308177934 9794774 complement(2447797..2449389) 1 NC_014550.1 catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX: protoporphyrinogen-IX + 1.5 O(2) <=> protoporphyrin-IX + 3 H(2)O. Also oxidizes the pathway intermediate coproporphyrinogen III: coproporphyrinogen-III + O2 <=> coproporphyrin-III + H2O; protoporphyrinogen oxidase 2449389 hemG 9794774 hemG Arthrobacter arilaitensis Re117 protoporphyrinogen oxidase YP_003917340.1 2447797 R 861360 CDS YP_003917341.1 308177935 9793955 complement(2449496..2450551) 1 NC_014550.1 fifth enzyme of the heme biosynthetic pathway, catalyzes the sequential decarboxylation of the four acetyl side chains of uroporphyrinogen to yield coproporphyrinogen: Uroporphyrinogen III <=> coproporphyrinogen + 4 CO(2) and uroporphyrinogen I <=> coproporphyrinogen I + CO2; uroporphyrinogen decarboxylase 2450551 hemE 9793955 hemE Arthrobacter arilaitensis Re117 uroporphyrinogen decarboxylase YP_003917341.1 2449496 R 861360 CDS YP_003917342.1 308177936 9793953 2450700..2452019 1 NC_014550.1 catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA): L-glutamate 1- semialdehyde + NADP+ + tRNA(Glu) <=>L-glutamyl-tRNA(Glu) + NADPH; glutamyl-tRNA reductase 2452019 hemA 9793953 hemA Arthrobacter arilaitensis Re117 glutamyl-tRNA reductase YP_003917342.1 2450700 D 861360 CDS YP_003917343.1 308177937 9793948 2452158..2452781 1 NC_014550.1 match to PF00440: bacterial regulatory proteins, tetR family; transcriptional regulator 2452781 9793948 AARI_21520 Arthrobacter arilaitensis Re117 transcriptional regulator YP_003917343.1 2452158 D 861360 CDS YP_003917344.1 308177938 9794775 2452846..2453067 1 NC_014550.1 hypothetical protein 2453067 9794775 AARI_21530 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917344.1 2452846 D 861360 CDS YP_003917345.1 308177939 9794776 2453223..2454635 1 NC_014550.1 exoribonuclease II catalyses the exonucleolytic cleavage in the 3- to 5-direction to yield nucleoside 5- phosphates. It is involved in mRNA degradation and tRNA precursor end processing; exoribonuclease II 2454635 9794776 AARI_21540 Arthrobacter arilaitensis Re117 exoribonuclease II YP_003917345.1 2453223 D 861360 CDS YP_003917346.1 308177940 9794777 2454900..2456516 1 NC_014550.1 DEAD box helicase. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression; ATP-dependent RNA helicase 2456516 9794777 AARI_21550 Arthrobacter arilaitensis Re117 ATP-dependent RNA helicase YP_003917346.1 2454900 D 861360 CDS YP_003917347.1 308177941 9794778 2456568..2457494 1 NC_014550.1 match to PF01555. This domain is found in DNA methylases. In prokaryotes, the major role of DNA methylation is to protect host DNA against degradation by restriction enzymes. This family contains both N-4 cytosine-specific DNA methylases (EC 2.1.1.113) and N-6 Adenine-specific DNA methylases (2.1.1.72); site-specific DNA-methyltransferase 2457494 9794778 AARI_21560 Arthrobacter arilaitensis Re117 site-specific DNA-methyltransferase YP_003917347.1 2456568 D 861360 CDS YP_003917348.1 308177942 9794779 complement(2457464..2458309) 1 NC_014550.1 match to PF02811. The PHP (Polymerase and Histidinol Phosphatase) domain is a phosphoesterase domain; PHP domain-containing protein 2458309 9794779 AARI_21570 Arthrobacter arilaitensis Re117 PHP domain-containing protein YP_003917348.1 2457464 R 861360 CDS YP_003917349.1 308177943 9794780 2458375..2459922 1 NC_014550.1 responsible for the release of any N-terminal amino acid adjacent to a proline residue; Xaa-Pro aminopeptidase 2459922 pepP 9794780 pepP Arthrobacter arilaitensis Re117 Xaa-Pro aminopeptidase YP_003917349.1 2458375 D 861360 CDS YP_003917350.1 308177944 9794195 complement(2460030..2460944) 1 NC_014550.1 2 transmembrane helices predicted by TMHMM2.0; hypothetical protein 2460944 9794195 AARI_21590 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917350.1 2460030 R 861360 CDS YP_003917351.1 308177945 9794781 2461089..2462327 1 NC_014550.1 match to PF00571 (CBS domain pair); CBS domain-containing protein 2462327 9794781 AARI_21600 Arthrobacter arilaitensis Re117 CBS domain-containing protein YP_003917351.1 2461089 D 861360 CDS YP_003917352.1 308177946 9794782 2462373..2462981 1 NC_014550.1 2 transmembrane helices predicted by TMHMM2.0; hypothetical protein 2462981 9794782 AARI_21610 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917352.1 2462373 D 861360 CDS YP_003917353.1 308177947 9794783 2462985..2464088 1 NC_014550.1 hypothetical protein 2464088 9794783 AARI_21620 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917353.1 2462985 D 861360 CDS YP_003917354.1 308177948 9794784 complement(2464101..2464505) 1 NC_014550.1 the twin-arginine translocation system is a Sec- independent exporter for folded proteins, often with a redox cofactor already bound, across the bacterial inner membrane; twin-arginine translocation protein TatB 2464505 tatB 9794784 tatB Arthrobacter arilaitensis Re117 twin-arginine translocation protein TatB YP_003917354.1 2464101 R 861360 CDS YP_003917355.1 308177949 9794426 complement(2464583..2465167) 1 NC_014550.1 match to protein family TIGR02937. Sigma-70 family; RNA polymerase sigma factor 2465167 9794426 AARI_21640 Arthrobacter arilaitensis Re117 RNA polymerase sigma factor YP_003917355.1 2464583 R 861360 CDS YP_003917356.1 308177950 9794785 2465339..2466004 1 NC_014550.1 match to PF01596. This family includes catechol o- methyltransferase, caffeoyl-CoA O-methyltransferase and a family of bacterial O-methyltransferases that may be involved in antibiotic production; O-methyltransferase 2466004 9794785 AARI_21650 Arthrobacter arilaitensis Re117 O-methyltransferase YP_003917356.1 2465339 D 861360 CDS YP_003917357.1 308177951 9794786 complement(2466096..2466263) 1 NC_014550.1 hypothetical protein 2466263 9794786 AARI_21660 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917357.1 2466096 R 861360 CDS YP_003917358.1 308177952 9794787 complement(2466387..2466731) 1 NC_014550.1 signal peptide predicted by SignalP 3.0 HMM (probability: 0.848) with cleavage site probability 0.238 between position 22 and 23; hypothetical protein 2466731 9794787 AARI_21670 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917358.1 2466387 R 861360 CDS YP_003917359.1 308177953 9794788 complement(2466735..2467520) 1 NC_014550.1 match to protein family PF03641: Possible lysine decarboxylase. The members of this family share a highly conserved motif PGGXGTXXE that is probably functionally important. This family includes proteins annotated as lysine decarboxylases, although the evidence for this is not clear; hypothetical protein 2467520 9794788 AARI_21680 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917359.1 2466735 R 861360 CDS YP_003917360.1 308177954 9794789 2467656..2468429 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, polar amino acid uptake transporter (PAAT) family, glutamate porter (TC 3.A.1.3.9). ABCISSE: ABC transporter, ATP- binding protein (ABC), PAO-family (polar amino acid and opines). Part of the ABC transporter complex gluABCD involved in glutamate import; glutamate ABC transporter ATP-binding subunit GluA 2468429 gluA 9794789 gluA Arthrobacter arilaitensis Re117 glutamate ABC transporter ATP-binding subunit GluA YP_003917360.1 2467656 D 861360 CDS YP_003917361.1 308177955 9793921 2468461..2469291 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, polar amino acid uptake transporter (PAAT) family, glutamate porter (TC 3.A.1.3.9). ABCISSE: ABC transporter, binding protein (BP), PAO-family (polar amino acid and opines). Part of the ABC transporter complex gluABCD involved in glutamate import; glutamate ABC transporter substrate-binding protein GluB 2469291 gluB 9793921 gluB Arthrobacter arilaitensis Re117 glutamate ABC transporter substrate-binding protein GluB YP_003917361.1 2468461 D 861360 CDS YP_003917362.1 308177956 9793922 2469431..2470108 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, polar amino acid uptake transporter (PAAT) family, glutamate porter (TC 3.A.1.3.9). ABCISSE: ABC transporter, permease (IM), PAO-family (polar amino acid and opines). Part of the ABC transporter complex gluABCD involved in glutamate import; glutamate ABC transporter inner membrane subunit GluC 2470108 gluC 9793922 gluC Arthrobacter arilaitensis Re117 glutamate ABC transporter inner membrane subunit GluC YP_003917362.1 2469431 D 861360 CDS YP_003917363.1 308177957 9793923 2470105..2471016 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, polar amino acid uptake transporter (PAAT) family, glutamate porter (TC 3.A.1.3.9). ABCISSE: ABC transporter, permease (IM), PAO-family (polar amino acid and opines). Part of the ABC transporter complex gluABCD involved in glutamate import; glutamate ABC transporter inner membrane subunit GluD 2471016 gluD 9793923 gluD Arthrobacter arilaitensis Re117 glutamate ABC transporter inner membrane subunit GluD YP_003917363.1 2470105 D 861360 CDS YP_003917364.1 308177958 9793924 complement(2471110..2472186) 1 NC_014550.1 catalyzes the fifth step in the biosynthesis of lysine from aspartate semialdehyde: the hydrolysis of succinyl-diaminopimelate to diaminopimelate and succinate; succinyl-diaminopimelate desuccinylase 2472186 dapE 9793924 dapE Arthrobacter arilaitensis Re117 succinyl-diaminopimelate desuccinylase YP_003917364.1 2471110 R 861360 CDS YP_003917365.1 308177959 9793792 2472268..2473221 1 NC_014550.1 involved in the biosynthesis of diaminopimelate and lysine from aspartate semialdehyde (EC 2.3.1.117); 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase 2473221 dapD 9793792 dapD Arthrobacter arilaitensis Re117 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase YP_003917365.1 2472268 D 861360 CDS YP_003917366.1 308177960 9793791 complement(2473285..2473893) 1 NC_014550.1 hypothetical protein 2473893 9793791 AARI_21750 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917366.1 2473285 R 861360 CDS YP_003917367.1 308177961 9794790 complement(2474035..2475321) 1 NC_014550.1 catalyzes the synthesis of citrate from oxaloacetate and acetyl-CoA. Involved in TCA cycle; citrate synthase 2475321 gltA 9794790 gltA Arthrobacter arilaitensis Re117 citrate synthase YP_003917367.1 2474035 R 861360 CDS YP_003917368.1 308177962 9793917 complement(2475420..2476535) 1 NC_014550.1 catalyzes the formation of N-succinyl-LL-2,6- diaminopimelate from N-succinyl-L-2-amino-6-oxopimelate in lysine biosynthesis; succinyldiaminopimelate transaminase 2476535 dapC 9793917 dapC Arthrobacter arilaitensis Re117 succinyldiaminopimelate transaminase YP_003917368.1 2475420 R 861360 CDS YP_003917369.1 308177963 9793790 complement(2476548..2476871) 1 NC_014550.1 match to protein domain PF00037: 4Fe-4S binding domain. Superfamily includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases; 4Fe-4S ferredoxin domain-containing protein 2476871 9793790 AARI_21780 Arthrobacter arilaitensis Re117 4Fe-4S ferredoxin domain-containing protein YP_003917369.1 2476548 R 861360 CDS YP_003917370.1 308177964 9794791 2477086..2477328 1 NC_014550.1 hypothetical protein 2477328 9794791 AARI_21790 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917370.1 2477086 D 861360 CDS YP_003917371.1 308177965 9794792 2477452..2477961 1 NC_014550.1 identified by match to PF01022. ArsR-family transcriptional regulators include several proteins that appear to dissociate from DNA in the presence of metal ions; ArsR family transcriptional regulator 2477961 9794792 AARI_21800 Arthrobacter arilaitensis Re117 ArsR family transcriptional regulator YP_003917371.1 2477452 D 861360 CDS YP_003917372.1 308177966 9794793 complement(2478032..2478463) 1 NC_014550.1 4 transmembrane helices predicted by TMHMM2.0; hypothetical protein 2478463 9794793 AARI_21810 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917372.1 2478032 R 861360 CDS YP_003917373.1 308177967 9794794 complement(2478444..2480351) 1 NC_014550.1 match to protein family TIGR01394. This bacterial (and Arabidopsis) protein, termed TypA or BipA, a GTP- binding protein, is phosphorylated on a tyrosine residue under some cellular conditions. Mutants show altered regulation of some pathways, but the precise function is unknown; GTP-binding protein TypA 2480351 typA 9794794 typA Arthrobacter arilaitensis Re117 GTP-binding protein TypA YP_003917373.1 2478444 R 861360 CDS YP_003917374.1 308177968 9794484 complement(2480499..2481041) 1 NC_014550.1 identified by match to PF00583: acetyltransferase (GNAT) family; GNAT family acetyltransferase 2481041 9794484 AARI_21830 Arthrobacter arilaitensis Re117 GNAT family acetyltransferase YP_003917374.1 2480499 R 861360 CDS YP_003917375.1 308177969 9794795 complement(2481073..2482218) 1 NC_014550.1 catalyzes the adenylation by ATP of the carboxyl- terminal glycine of ThiS, as part of the biosynthesis pathway of thiamin pyrophosphate (vitamin B1); adenylyltransferase ThiF 2482218 thiF 9794795 thiF Arthrobacter arilaitensis Re117 adenylyltransferase ThiF YP_003917375.1 2481073 R 861360 CDS YP_003917376.1 308177970 9794442 complement(2482215..2483036) 1 NC_014550.1 involved in the formation of the thiazole moiety of thiamin pyrophosphate: catalyzes the formation of thiazole from 1-deoxy-D-xylulose 5-phosphate (DXP) and dehydroglycine, with the help of the sulfur carrier protein ThiS; thiazole synthase 2483036 thiG 9794442 thiG Arthrobacter arilaitensis Re117 thiazole synthase YP_003917376.1 2482215 R 861360 CDS YP_003917377.1 308177971 9794443 complement(2483039..2483299) 1 NC_014550.1 sulfur carrier protein involved in thiamin biosynthesis : carries the sulfur needed for thiazole assembly on its carboxy terminus (ThiS-COSH); thiamin synthesis protein ThiS 2483299 thiS 9794443 thiS Arthrobacter arilaitensis Re117 thiamin synthesis protein ThiS YP_003917377.1 2483039 R 861360 CDS YP_003917378.1 308177972 9794447 complement(2483300..2484412) 1 NC_014550.1 required for the biosynthesis of the thiazole moiety of thiamine diphosphate; glycine oxidase 2484412 thiO 9794447 thiO Arthrobacter arilaitensis Re117 glycine oxidase YP_003917378.1 2483300 R 861360 CDS YP_003917379.1 308177973 9794446 2484594..2485559 1 NC_014550.1 N-terminal section of the protein: RNaseH. C-terminal section of the protein: GNAT-family acetyltransferase; hypothetical protein 2485559 9794446 AARI_21880 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917379.1 2484594 D 861360 CDS YP_003917380.1 308177974 9794796 complement(2485643..2486863) 1 NC_014550.1 9 transmembrane helices predicted by TMHMM2.0; hypothetical protein 2486863 9794796 AARI_21890 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917380.1 2485643 R 861360 CDS YP_003917381.1 308177975 9794797 complement(2487159..2487590) 1 NC_014550.1 identified by match to protein family PF02566: OsmC, OsmC-like protein. Osmotically inducible protein C (OsmC) is a stress-induced protein found in Escherichia coli. This family also contains an organic hydroperoxide detoxification protein that has a novel pattern of oxidative stress regulation; OsmC-like protein 2487590 9794797 AARI_21900 Arthrobacter arilaitensis Re117 OsmC-like protein YP_003917381.1 2487159 R 861360 CDS YP_003917382.1 308177976 9794798 complement(2487622..2488056) 1 NC_014550.1 identified by match to PF00583: acetyltransferase (GNAT) family; GNAT family acetyltransferase 2488056 9794798 AARI_21910 Arthrobacter arilaitensis Re117 GNAT family acetyltransferase YP_003917382.1 2487622 R 861360 CDS YP_003917383.1 308177977 9794799 complement(2488124..2488957) 1 NC_014550.1 match to PF00561: alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes; hydrolase 2488957 9794799 AARI_21920 Arthrobacter arilaitensis Re117 hydrolase YP_003917383.1 2488124 R 861360 CDS YP_003917384.1 308177978 9794800 complement(2488948..2489667) 1 NC_014550.1 6 transmembrane helices predicted by TMHMM2.0. Match to PF07947. The members of this family are similar to the hypothetical protein yhhN expressed by E. coli. Many of the members of this family are annotated as being possible transmembrane proteins, and in fact they all have a high proportion of hydrophobic residues; YhhN-like protein 2489667 9794800 AARI_21930 Arthrobacter arilaitensis Re117 YhhN-like protein YP_003917384.1 2488948 R 861360 CDS YP_003917385.1 308177979 9794801 complement(2489710..2490390) 1 NC_014550.1 match to protein family PF00903: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; hypothetical protein 2490390 9794801 AARI_21940 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917385.1 2489710 R 861360 CDS YP_003917386.1 308177980 9794802 2490720..2490848 1 NC_014550.1 hypothetical protein 2490848 9794802 AARI_21950 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917386.1 2490720 D 861360 CDS YP_003917387.1 308177981 9794803 complement(2490869..2491003) 1 NC_014550.1 hypothetical protein 2491003 9794803 AARI_21960 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917387.1 2490869 R 861360 CDS YP_003917388.1 308177982 9794804 2491164..2492051 1 NC_014550.1 identified by match to PF00583: acetyltransferase (GNAT) family; GNAT family acetyltransferase 2492051 9794804 AARI_21970 Arthrobacter arilaitensis Re117 GNAT family acetyltransferase YP_003917388.1 2491164 D 861360 CDS YP_003917389.1 308177983 9794805 2492048..2492542 1 NC_014550.1 hypothetical protein 2492542 9794805 AARI_21980 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917389.1 2492048 D 861360 CDS YP_003917390.1 308177984 9794806 complement(2492539..2493276) 1 NC_014550.1 8 transmembrane helices predicted by TMHMM2.0; hypothetical protein 2493276 9794806 AARI_21990 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917390.1 2492539 R 861360 CDS YP_003917391.1 308177985 9794807 2493421..2493852 1 NC_014550.1 4 transmembrane helices predicted by TMHMM2.0; hypothetical protein 2493852 9794807 AARI_22000 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917391.1 2493421 D 861360 CDS YP_003917392.1 308177986 9794808 2493858..2494145 1 NC_014550.1 transcriptional regulator 2494145 9794808 AARI_22010 Arthrobacter arilaitensis Re117 transcriptional regulator YP_003917392.1 2493858 D 861360 CDS YP_003917393.1 308177987 9794809 2494183..2494800 1 NC_014550.1 hypothetical protein 2494800 9794809 AARI_22020 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917393.1 2494183 D 861360 CDS YP_003917394.1 308177988 9794810 complement(2494797..2495879) 1 NC_014550.1 permease 2495879 9794810 AARI_22030 Arthrobacter arilaitensis Re117 permease YP_003917394.1 2494797 R 861360 CDS YP_003917395.1 308177989 9794811 complement(2495938..2496699) 1 NC_014550.1 hypothetical protein 2496699 9794811 AARI_22040 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917395.1 2495938 R 861360 CDS YP_003917396.1 308177990 9794812 complement(2496806..2497306) 1 NC_014550.1 identified by match to PF00583: acetyltransferase (GNAT) family; GNAT family acetyltransferase 2497306 9794812 AARI_22050 Arthrobacter arilaitensis Re117 GNAT family acetyltransferase YP_003917396.1 2496806 R 861360 CDS YP_003917397.1 308177991 9794813 complement(2497335..2497721) 1 NC_014550.1 match to protein family PF00903: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; hypothetical protein 2497721 9794813 AARI_22060 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917397.1 2497335 R 861360 CDS YP_003917398.1 308177992 9794814 complement(2497771..2498310) 1 NC_014550.1 identified by match to PF00583: acetyltransferase (GNAT) family; GNAT family acetyltransferase 2498310 9794814 AARI_22070 Arthrobacter arilaitensis Re117 GNAT family acetyltransferase YP_003917398.1 2497771 R 861360 CDS YP_003917399.1 308177993 9794815 2498494..2498787 1 NC_014550.1 hypothetical protein 2498787 9794815 AARI_22080 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917399.1 2498494 D 861360 CDS YP_003917400.1 308177994 9794816 2498966..2499544 1 NC_014550.1 involved in phospholipid biosynthesis; CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 2499544 pgsA 9794816 pgsA Arthrobacter arilaitensis Re117 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase YP_003917400.1 2498966 D 861360 CDS YP_003917401.1 308177995 9794202 complement(2499559..2500065) 1 NC_014550.1 match to PF02834. Corresponds to a number of known and predicted phosphoesterases, including bacterial and archaeal 2 ,5 RNA ligases. The physiological substrate(s) in prokaryotes may include small 2 ,5 -link-containing oligonucleotides, perhaps with regulatory or biosynthetic roles; 2',5' RNA ligase family protein 2500065 9794202 AARI_22100 Arthrobacter arilaitensis Re117 2',5' RNA ligase family protein YP_003917401.1 2499559 R 861360 CDS YP_003917402.1 308177996 9794817 complement(2500065..2500616) 1 NC_014550.1 identified by match to PF00583: acetyltransferase (GNAT) family; GNAT family acetyltransferase 2500616 9794817 AARI_22110 Arthrobacter arilaitensis Re117 GNAT family acetyltransferase YP_003917402.1 2500065 R 861360 CDS YP_003917403.1 308177997 9794818 complement(2500636..2501361) 1 NC_014550.1 identified by match to protein domain PF08241; SAM-dependent methyltransferase 2501361 9794818 AARI_22120 Arthrobacter arilaitensis Re117 SAM-dependent methyltransferase YP_003917403.1 2500636 R 861360 CDS YP_003917404.1 308177998 9794819 2501623..2502771 1 NC_014550.1 acetyl-CoA C-acyltransferase (also named 3-ketoacyl- CoA thiolase or thiolase I) has a broad chain-length specificity for its substrates and is involved in degradative pathways such as fatty acid beta-oxidation; acetyl-CoA C-acyltransferase 2502771 fadA 9794819 fadA Arthrobacter arilaitensis Re117 acetyl-CoA C-acyltransferase YP_003917404.1 2501623 D 861360 CDS YP_003917405.1 308177999 9793843 2502796..2504388 1 NC_014550.1 long-chain-fatty-acid--CoA ligase activates long- chain fatty acids for both the synthesis of cellular lipids and their degradation via beta-oxidation; long-chain-fatty-acid--CoA ligase 2504388 9793843 AARI_22140 Arthrobacter arilaitensis Re117 long-chain-fatty-acid--CoA ligase YP_003917405.1 2502796 D 861360 CDS YP_003917406.1 308178000 9794820 2504385..2505584 1 NC_014550.1 possibly involved in the metabolism of lipids. Match to protein domains PF08028, PF02771 and PF02770. Acyl-CoA dehydrogenases catalyze the alpha,beta- dehydrogenation of acyl-CoA thioesters to the corresponding trans 2,3-enoyl CoA-products with concommitant reduction of enzyme-bound FAD; acyl-CoA dehydrogenase 2505584 9794820 AARI_22150 Arthrobacter arilaitensis Re117 acyl-CoA dehydrogenase YP_003917406.1 2504385 D 861360 CDS YP_003917407.1 308178001 9794821 2505650..2506114 1 NC_014550.1 hypothetical protein 2506114 9794821 AARI_22160 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917407.1 2505650 D 861360 CDS YP_003917408.1 308178002 9794822 complement(2506127..2506978) 1 NC_014550.1 identified by match to PF00753: metallo-beta- lactamase superfamily. Apart from the beta-lactamases, a number of other proteins contain this domain. These proteins include thiolesterases, members of the glyoxalase II family, that catalyse the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid and a competence protein that is essential for natural transformation in Neisseria gonorrhoeae and could be a transporter involved in DNA uptake; metallo-beta-lactamase 2506978 9794822 AARI_22170 Arthrobacter arilaitensis Re117 metallo-beta-lactamase YP_003917408.1 2506127 R 861360 CDS YP_003917409.1 308178003 9794823 complement(2507008..2507973) 1 NC_014550.1 identified by match to protein family PF00849. Pseudouridylate synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5- ribosyluracil, psi); pseudouridylate synthase 2507973 9794823 AARI_22180 Arthrobacter arilaitensis Re117 pseudouridylate synthase YP_003917409.1 2507008 R 861360 CDS YP_003917410.1 308178004 9794824 complement(2508193..2508747) 1 NC_014550.1 5 transmembrane helices predicted by TMHMM2.0; hypothetical protein 2508747 9794824 AARI_22190 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917410.1 2508193 R 861360 CDS YP_003917411.1 308178005 9794825 2509009..2509476 1 NC_014550.1 hypothetical protein 2509476 9794825 AARI_22200 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917411.1 2509009 D 861360 CDS YP_003917412.1 308178006 9794826 complement(2509504..2509668) 1 NC_014550.1 hypothetical protein 2509668 9794826 AARI_22210 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917412.1 2509504 R 861360 CDS YP_003917413.1 308178007 9794827 2509794..2510477 1 NC_014550.1 identified by match to protein domain PF00300; phosphoglycerate mutase family protein 2510477 9794827 AARI_22220 Arthrobacter arilaitensis Re117 phosphoglycerate mutase family protein YP_003917413.1 2509794 D 861360 CDS YP_003917414.1 308178008 9794828 2510488..2511027 1 NC_014550.1 hypothetical protein 2511027 9794828 AARI_22230 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917414.1 2510488 D 861360 CDS YP_003917415.1 308178009 9794829 2511024..2511791 1 NC_014550.1 match to protein family PF00454. This domain is present in a wide range of protein kinases, involved in diverse cellular functions; phosphatidylinositol 3-and 4-kinase family protein 2511791 9794829 AARI_22240 Arthrobacter arilaitensis Re117 phosphatidylinositol 3-and 4-kinase family protein YP_003917415.1 2511024 D 861360 CDS YP_003917416.1 308178010 9794830 complement(2511813..2512442) 1 NC_014550.1 2 transmembrane helices predicted by TMHMM2.0; hypothetical protein 2512442 9794830 AARI_22250 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917416.1 2511813 R 861360 CDS YP_003917417.1 308178011 9794831 2512614..2513309 1 NC_014550.1 identified by match to PF00106. The short-chain dehydrogenases/reductases family (SDR) is a very large family of enzymes, most of which are known to be NAD- or NADP-dependent oxidoreductases; short-chain dehydrogenases/reductases family protein 2513309 9794831 AARI_22260 Arthrobacter arilaitensis Re117 short-chain dehydrogenases/reductases family protein YP_003917417.1 2512614 D 861360 CDS YP_003917418.1 308178012 9794832 2513405..2514244 1 NC_014550.1 match to PF00561: alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes; hydrolase 2514244 9794832 AARI_22270 Arthrobacter arilaitensis Re117 hydrolase YP_003917418.1 2513405 D 861360 CDS YP_003917419.1 308178013 9794833 2514292..2514678 1 NC_014550.1 hypothetical protein 2514678 9794833 AARI_22280 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917419.1 2514292 D 861360 CDS YP_003917420.1 308178014 9794834 2514863..2515156 1 NC_014550.1 hypothetical protein 2515156 9794834 AARI_22290 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917420.1 2514863 D 861360 CDS YP_003917421.1 308178015 9794835 complement(2515177..2515410) 1 NC_014550.1 2 transmembrane helices predicted by TMHMM2.0; hypothetical protein 2515410 9794835 AARI_22300 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917421.1 2515177 R 861360 CDS YP_003917422.1 308178016 9794836 complement(2515742..2516731) 1 NC_014550.1 match to protein domain PF02861: Clp amino terminal domain. This short domain is found in one or two copies at the amino terminus of ClpA and ClpB proteins from bacteria and eukaryotes. The function of these domains is uncertain but they may form a protein binding site. The proteins are thought to be subunits of ATP-dependent proteases which act as chaperones to target the proteases to substrates; hypothetical protein 2516731 9794836 AARI_22310 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917422.1 2515742 R 861360 CDS YP_003917423.1 308178017 9794837 complement(2516728..2516973) 1 NC_014550.1 possible DNA-binding protein. Match to protein domain IPR009057: homeodomain-like; hypothetical protein 2516973 9794837 AARI_22320 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917423.1 2516728 R 861360 CDS YP_003917424.1 308178018 9793484 2518415..2518561 1 NC_014550.1 hypothetical protein 2518561 9793484 AARI_22330 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917424.1 2518415 D 861360 CDS YP_003917425.1 308178019 9794839 complement(2518744..2520459) 1 NC_014550.1 catalyses the conversion of D-lactate to pyruvate. Probable quinone-dependent lactate dehydrogenase, functionning when lactate is used as a carbon and energy source; D-lactate dehydrogenase 2520459 dld 9794839 dld Arthrobacter arilaitensis Re117 D-lactate dehydrogenase YP_003917425.1 2518744 R 861360 CDS YP_003917426.1 308178020 9793819 complement(2520838..2521728) 1 NC_014550.1 match to PF01555. This domain is found in DNA methylases. In prokaryotes, the major role of DNA methylation is to protect host DNA against degradation by restriction enzymes. Match to PS00092 pattern: N-6 Adenine- specific DNA methylases signature; site-specific DNA-methyltransferase (adenine specific) 2521728 9793819 AARI_22350 Arthrobacter arilaitensis Re117 site-specific DNA-methyltransferase (adenine specific) YP_003917426.1 2520838 R 861360 CDS YP_003917427.1 308178021 9794840 complement(2521909..2522988) 1 NC_014550.1 transposase of ISAar18, IS110 family 2522988 9794840 AARI_35440 Arthrobacter arilaitensis Re117 transposase of ISAar18, IS110 family YP_003917427.1 2521909 R 861360 CDS YP_003917428.1 308178022 9793485 2523435..2524631 1 NC_014550.1 transposase of ISAar17, IS110 family 2524631 9793485 AARI_35450 Arthrobacter arilaitensis Re117 transposase of ISAar17, IS110 family YP_003917428.1 2523435 D 861360 CDS YP_003917429.1 308178023 9793486 2524628..2524858 1 NC_014550.1 hypothetical protein 2524858 9793486 AARI_22360 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917429.1 2524628 D 861360 CDS YP_003917430.1 308178024 9794841 complement(2524892..2525995) 1 NC_014550.1 identified by match to protein family TIGR00092: GTP-binding protein YchF; translation-associated GTPase 2525995 9794841 AARI_22370 Arthrobacter arilaitensis Re117 translation-associated GTPase YP_003917430.1 2524892 R 861360 CDS YP_003917431.1 308178025 9794842 complement(2526074..2527159) 1 NC_014550.1 forms part of the non-mevalonate pathway for terpenoid biosynthesis; 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 2527159 ispH 9794842 ispH Arthrobacter arilaitensis Re117 4-hydroxy-3-methylbut-2-enyl diphosphate reductase YP_003917431.1 2526074 R 861360 CDS YP_003917432.1 308178026 9794014 2527365..2528627 1 NC_014550.1 exodeoxyribonuclease VII catalyses the exonucleolytic cleavage in either 5 - to 3 - or 3 - to 5 - direction to yield nucleoside 5-phosphates. In E. coli, ExoVII plays a role in methyl-directed mismatch repair in vivo. ExoVII may also guard the genome from mutagenesis by removing excess ssDNA, since the build up of ssDNA would lead to SOS induction and PolIV-dependent mutagenesis; exodeoxyribonuclease VII large subunit 2528627 xseA 9794014 xseA Arthrobacter arilaitensis Re117 exodeoxyribonuclease VII large subunit YP_003917432.1 2527365 D 861360 CDS YP_003917433.1 308178027 9794509 2528656..2528886 1 NC_014550.1 exodeoxyribonuclease VII catalyses the exonucleolytic cleavage in either 5 - to 3 - or 3 - to 5 - direction to yield nucleoside 5-phosphates. In E. coli, ExoVII plays a role in methyl-directed mismatch repair in vivo. ExoVII may also guard the genome from mutagenesis by removing excess ssDNA, since the build up of ssDNA would lead to SOS induction and PolIV-dependent mutagenesis; exodeoxyribonuclease VII small subunit 2528886 xseB 9794509 xseB Arthrobacter arilaitensis Re117 exodeoxyribonuclease VII small subunit YP_003917433.1 2528656 D 861360 CDS YP_003917434.1 308178028 9794510 complement(2528907..2529770) 1 NC_014550.1 identified by match to protein domain PF03976. This domain is about 230 amino acids in length and has polyphosphate kinase activity; polyphosphate kinase domain-containing protein 2529770 9794510 AARI_22410 Arthrobacter arilaitensis Re117 polyphosphate kinase domain-containing protein YP_003917434.1 2528907 R 861360 CDS YP_003917435.1 308178029 9794843 2529800..2529958 1 NC_014550.1 hypothetical protein 2529958 9794843 AARI_22420 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917435.1 2529800 D 861360 CDS YP_003917436.1 308178030 9794844 complement(2530052..2531272) 1 NC_014550.1 catalyses the following reaction: L-alanine + 2- oxoglutarate <=> pyruvate + L-glutamate; alanine transaminase 2531272 alaT 9794844 alaT Arthrobacter arilaitensis Re117 alanine transaminase YP_003917436.1 2530052 R 861360 CDS YP_003917437.1 308178031 9793661 complement(2531365..2532270) 1 NC_014550.1 match to PS51257: prokaryotic membrane lipoprotein lipid attachment site profile; hypothetical protein 2532270 9793661 AARI_22440 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917437.1 2531365 R 861360 CDS YP_003917438.1 308178032 9794845 complement(2532423..2532782) 1 NC_014550.1 identified by match to PF00293. Members of the Nudix hydrolase superfamily catalyze the hydrolysis of nucleoside diphosphates linked to other moieties. Substrates of nudix hydrolases include intact and oxidatively damaged nucleoside triphosphates, dinucleoside polyphosphates, nucleotide-sugars and dinucleotide enzymes. These substrates are metabolites or cell signaling molecules that require regulation during different stages of the cell cycle or during periods of stress. In general, the role of the nudix hydrolase is to sanitize the nucleotide pools and to maintain cell viability, thereby serving as surveillance and house- cleaning enzymes; NUDIX hydrolase 2532782 9794845 AARI_22450 Arthrobacter arilaitensis Re117 NUDIX hydrolase YP_003917438.1 2532423 R 861360 CDS YP_003917439.1 308178033 9794846 2532895..2533401 1 NC_014550.1 identified by match to protein family PF01037; AsnC/Lrp family transcriptional regulator 2533401 9794846 AARI_22460 Arthrobacter arilaitensis Re117 AsnC/Lrp family transcriptional regulator YP_003917439.1 2532895 D 861360 CDS YP_003917440.1 308178034 9794847 complement(2533474..2534307) 1 NC_014550.1 hypothetical protein 2534307 9794847 AARI_22470 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917440.1 2533474 R 861360 CDS YP_003917441.1 308178035 9794848 complement(2534488..2535108) 1 NC_014550.1 identified by match to PF00583: acetyltransferase (GNAT) family; GNAT family acetyltransferase 2535108 9794848 AARI_22480 Arthrobacter arilaitensis Re117 GNAT family acetyltransferase YP_003917441.1 2534488 R 861360 CDS YP_003917442.1 308178036 9794849 2535194..2535808 1 NC_014550.1 catalyses the following reaction: ATP + 5- formyltetrahydrofolate => ADP + phosphate + 5,10- methenyltetrahydrofolate; 5-formyltetrahydrofolate cyclo-ligase 2535808 9794849 AARI_22490 Arthrobacter arilaitensis Re117 5-formyltetrahydrofolate cyclo-ligase YP_003917442.1 2535194 D 861360 CDS YP_003917443.1 308178037 9794850 2535870..2536580 1 NC_014550.1 hypothetical protein 2536580 9794850 AARI_22500 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917443.1 2535870 D 861360 CDS YP_003917444.1 308178038 9794851 complement(2536583..2536900) 1 NC_014550.1 hypothetical protein 2536900 9794851 AARI_22510 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917444.1 2536583 R 861360 CDS YP_003917445.1 308178039 9794852 complement(2536900..2541174) 1 NC_014550.1 hypothetical protein 2541174 9794852 AARI_22520 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917445.1 2536900 R 861360 CDS YP_003917446.1 308178040 9794853 complement(2541383..2541913) 1 NC_014550.1 hypothetical protein 2541913 9794853 AARI_22530 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917446.1 2541383 R 861360 CDS YP_003917447.1 308178041 9794854 complement(2542091..2543677) 1 NC_014550.1 catalyzes the ATP-dependent formation of GMP from xanthosine 5-phosphate and glutamine; GMP synthase (glutamine-hydrolyzing) 2543677 guaA 9794854 guaA Arthrobacter arilaitensis Re117 GMP synthase (glutamine-hydrolyzing) YP_003917447.1 2542091 R 861360 CDS YP_003917448.1 308178042 9793940 complement(2543825..2544289) 1 NC_014550.1 3 transmembrane helices predicted by TMHMM2.0; hypothetical protein 2544289 9793940 AARI_22550 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917448.1 2543825 R 861360 CDS YP_003917449.1 308178043 9794855 complement(2544340..2545149) 1 NC_014550.1 signal peptide predicted by SignalP 3.0 HMM (probability: 0.976) with cleavage site probability 0.602 between position 37 and 38; hypothetical protein 2545149 9794855 AARI_22560 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917449.1 2544340 R 861360 CDS YP_003917450.1 308178044 9794856 complement(2545325..2546476) 1 NC_014550.1 catalyzes the NAD-dependent oxidation of IMP to XMP. Involved in the de novo synthesis of the guanine nucleotides; IMP dehydrogenase 2546476 guaB 9794856 guaB Arthrobacter arilaitensis Re117 IMP dehydrogenase YP_003917450.1 2545325 R 861360 CDS YP_003917451.1 308178045 9793941 complement(2546651..2547967) 1 NC_014550.1 hypothetical protein 2547967 9793941 AARI_22580 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917451.1 2546651 R 861360 CDS YP_003917452.1 308178046 9794857 2548217..2548771 1 NC_014550.1 signal peptide predicted by SignalP 3.0 HMM (probability: 1.000) with cleavage site probability 0.7762 between position 29 and 30; hypothetical protein 2548771 9794857 AARI_22590 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917452.1 2548217 D 861360 CDS YP_003917453.1 308178047 9794858 complement(2548968..2550473) 1 NC_014550.1 catalyzes the NAD-dependent oxidation of IMP to XMP. Involved in the de novo synthesis of the guanine nucleotides; IMP dehydrogenase 2550473 guaB 9794858 guaB Arthrobacter arilaitensis Re117 IMP dehydrogenase YP_003917453.1 2548968 R 861360 CDS YP_003917454.1 308178048 9793942 complement(2550594..2552690) 1 NC_014550.1 match to protein domain PF01757. This family includes a range of acyltransferase enzymes. 11 transmembrane helices predicted by TMHMM2.0; acyltransferase domain-containing membrane protein 2552690 9793942 AARI_22610 Arthrobacter arilaitensis Re117 acyltransferase domain-containing membrane protein YP_003917454.1 2550594 R 861360 CDS YP_003917455.1 308178049 9794859 2552926..2553108 1 NC_014550.1 hypothetical protein 2553108 9794859 AARI_22620 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917455.1 2552926 D 861360 CDS YP_003917456.1 308178050 9794860 complement(2553121..2554722) 1 NC_014550.1 chaperonins are involved in productive folding of proteins. With the aid of cochaperonin GroES, GroEL encapsulates non-native substrate proteins inside the cavity of the GroEL-ES complex and promotes folding by using energy derived from ATP hydrolysis; chaperonin GroEL 2554722 groEL 9794860 groEL Arthrobacter arilaitensis Re117 chaperonin GroEL YP_003917456.1 2553121 R 861360 CDS YP_003917457.1 308178051 9793937 complement(2554756..2555052) 1 NC_014550.1 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts; co-chaperonin GroES 2555052 groES 9793937 groES Arthrobacter arilaitensis Re117 co-chaperonin GroES YP_003917457.1 2554756 R 861360 CDS YP_003917458.1 308178052 9793938 complement(2555244..2556680) 1 NC_014550.1 amino acid-polyamine-organocation (APC) superfamily, amino acid transporter (AAT) family, lysine:H+ symporter (TC 2.A.3.1.2). Identified by similarity to protein SP:P25737 (Escherichia coli); lysine-specific permease 2556680 lysP 9793938 lysP Arthrobacter arilaitensis Re117 lysine-specific permease YP_003917458.1 2555244 R 861360 CDS YP_003917459.1 308178053 9794053 2557270..2558511 1 NC_014550.1 hypothetical protein 2558511 9794053 AARI_22660 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917459.1 2557270 D 861360 CDS YP_003917460.1 308178054 9794861 2558669..2559811 1 NC_014550.1 possible glutamate--cysteine ligase (6.3.2.2). Match to protein family PF04107: glutamate-cysteine ligase family 2(GCS2); carboxylate-amine ligase 2559811 9794861 AARI_22670 Arthrobacter arilaitensis Re117 carboxylate-amine ligase YP_003917460.1 2558669 D 861360 CDS YP_003917461.1 308178055 9794862 2560244..2560972 1 NC_014550.1 hypothetical protein 2560972 9794862 AARI_22680 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917461.1 2560244 D 861360 CDS YP_003917462.1 308178056 9794863 complement(2561203..2562015) 1 NC_014550.1 hypothetical protein 2562015 9794863 AARI_22690 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917462.1 2561203 R 861360 CDS YP_003917463.1 308178057 9794864 complement(2562053..2564092) 1 NC_014550.1 hypothetical protein 2564092 9794864 AARI_22700 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917463.1 2562053 R 861360 CDS YP_003917464.1 308178058 9794865 complement(2564461..2565135) 1 NC_014550.1 identified by match to protein family PF00392. This family of regulatory proteins consists of the N-terminal HTH region of GntR-like bacterial transcription factors. At the C-terminus there is usually an effector- binding/oligomerisation domain. The GntR-like proteins can be divided into six sub-families: MocR, YtrR, FadR, AraR, HutC and PlmA. Many of these proteins have been shown experimentally to be autoregulatory, enabling the prediction of operator sites and the discovery of cis/trans relationships; GntR family transcriptional regulator 2565135 9794865 AARI_22710 Arthrobacter arilaitensis Re117 GntR family transcriptional regulator YP_003917464.1 2564461 R 861360 CDS YP_003917465.1 308178059 9794866 complement(2565132..2566403) 1 NC_014550.1 major facilitator superfamily (TC 2.A.1.y.z). Identified by match to protein family PF07690 (Major Facilitator Superfamily); MFS superfamily transporter 2566403 9794866 AARI_22720 Arthrobacter arilaitensis Re117 MFS superfamily transporter YP_003917465.1 2565132 R 861360 CDS YP_003917466.1 308178060 9794868 2567037..2568344 1 NC_014550.1 transposase of ISAar19, ISL3 family 2568344 9794868 AARI_35460 Arthrobacter arilaitensis Re117 transposase of ISAar19, ISL3 family YP_003917466.1 2567037 D 861360 CDS YP_003917467.1 308178061 9793489 2570492..2571799 1 NC_014550.1 transposase of ISAar19, ISL3 family 2571799 9793489 AARI_35490 Arthrobacter arilaitensis Re117 transposase of ISAar19, ISL3 family YP_003917467.1 2570492 D 861360 CDS YP_003917468.1 308178062 9794871 2573924..2574253 1 NC_014550.1 hypothetical protein 2574253 9794871 AARI_22770 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917468.1 2573924 D 861360 CDS YP_003917469.1 308178063 9794873 2575668..2576975 1 NC_014550.1 transposase of ISAar19, ISL3 family 2576975 9794873 AARI_35500 Arthrobacter arilaitensis Re117 transposase of ISAar19, ISL3 family YP_003917469.1 2575668 D 861360 CDS YP_003917470.1 308178064 9793492 2578686..2579123 1 NC_014550.1 transposase of ISAar44, IS3 family, IS3 group, orfA 2579123 9793492 AARI_35520 Arthrobacter arilaitensis Re117 transposase of ISAar44, IS3 family, IS3 group, orfA YP_003917470.1 2578686 D 861360 CDS YP_003917471.1 308178065 9793493 2579222..2580163 1 NC_014550.1 transposase of ISAar44, IS3 family, IS3 group, orfB 2580163 9793493 AARI_35530 Arthrobacter arilaitensis Re117 transposase of ISAar44, IS3 family, IS3 group, orfB YP_003917471.1 2579222 D 861360 CDS YP_003917472.1 308178066 9793496 complement(2582709..2583125) 1 NC_014550.1 hypothetical protein 2583125 9793496 AARI_22790 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917472.1 2582709 R 861360 CDS YP_003917473.1 308178067 9794874 2583430..2584866 1 NC_014550.1 transposase of ISAar11, IS1380 family 2584866 9794874 AARI_35560 Arthrobacter arilaitensis Re117 transposase of ISAar11, IS1380 family YP_003917473.1 2583430 D 861360 CDS YP_003917474.1 308178068 9793498 complement(2586813..2587532) 1 NC_014550.1 hypothetical protein 2587532 9793498 AARI_22800 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917474.1 2586813 R 861360 CDS YP_003917475.1 308178069 9794875 complement(2587519..2590620) 1 NC_014550.1 type I restriction endonucleases are components of prokaryotic DNA restriction-modification mechanisms that protects the organism against invading foreign DNA. They have three different subunits subunits - M (modification), S (specificity) and R (restriction) - that form multifunctional enzymes with restriction (EC:3.1.21.3), methylase (EC:2.1.1.72) and ATPase activities. The S subunit is required for both restriction and modification and is responsible for recognition of the DNA sequence specific for the system. The M subunit is necessary for modification, and the R subunit is required for restriction. They recognize asymmetric DNA sequences split into two domains of specific sequence, one 3-4 bp long and another 4-5 bp long, separated by a nonspecific spacer 6-8 bp in length. Cleavage occurs a considerable distance from the recognition sites, rarely less than 400 bp away and up to 7000 bp away. Adenosyl residues are methylated, one on each strand of the recognition sequence; type I restriction-modification system restriction subunit 2590620 hsdR 9794875 hsdR Arthrobacter arilaitensis Re117 type I restriction-modification system restriction subunit YP_003917475.1 2587519 R 861360 CDS YP_003917476.1 308178070 9793981 complement(2590617..2591870) 1 NC_014550.1 type I restriction endonucleases are components of prokaryotic DNA restriction-modification mechanisms that protects the organism against invading foreign DNA. They have three different subunits: subunits - M (modification), S (specificity) and R (restriction) - that form multifunctional enzymes with restriction (EC:3.1.21.3), methylase (EC:2.1.1.72) and ATPase activities. The S subunit is required for both restriction and modification and is responsible for recognition of the DNA sequence specific for the system. The M subunit is necessary for modification, and the R subunit is required for restriction. They recognize asymmetric DNA sequences split into two domains of specific sequence, one 3-4 bp long and another 4-5 bp long, separated by a nonspecific spacer 6-8 bp in length. Cleavage occurs a considerable distance from the recognition sites, rarely less than 400 bp away and up to 7000 bp away. Adenosyl residues are methylated, one on each strand of the recognition sequence; type I restriction-modification system specificity subunit 2591870 hsdS 9793981 hsdS Arthrobacter arilaitensis Re117 type I restriction-modification system specificity subunit YP_003917476.1 2590617 R 861360 CDS YP_003917477.1 308178071 9793983 complement(2591867..2594317) 1 NC_014550.1 type I restriction endonucleases are components of prokaryotic DNA restriction-modification mechanisms that protects the organism against invading foreign DNA. They have three different subunits: subunits - M (modification), S (specificity) and R (restriction) - that form multifunctional enzymes with restriction (EC:3.1.21.3), methylase (EC:2.1.1.72) and ATPase activities. The S subunit is required for both restriction and modification and is responsible for recognition of the DNA sequence specific for the system. The M subunit is necessary for modification, and the R subunit is required for restriction. They recognize asymmetric DNA sequences split into two domains of specific sequence, one 3-4 bp long and another 4-5 bp long, separated by a nonspecific spacer 6-8 bp in length. Cleavage occurs a considerable distance from the recognition sites, rarely less than 400 bp away and up to 7000 bp away. Adenosyl residues are methylated, one on each strand of the recognition sequence; type I restriction-modification system modification subunit 2594317 hsdM 9793983 hsdM Arthrobacter arilaitensis Re117 type I restriction-modification system modification subunit YP_003917477.1 2591867 R 861360 CDS YP_003917478.1 308178072 9793978 2594988..2595539 1 NC_014550.1 1 transmembrane helice predicted by TMHMM2.0; hypothetical protein 2595539 9793978 AARI_22840 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917478.1 2594988 D 861360 CDS YP_003917479.1 308178073 9793500 complement(2596639..2596950) 1 NC_014550.1 hypothetical protein 2596950 9793500 AARI_22850 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917479.1 2596639 R 861360 CDS YP_003917480.1 308178074 9794877 complement(2597433..2598896) 1 NC_014550.1 glycoside hydrolase family 32 comprises enzymes with several known activities: invertase (EC 3.2.1.26); inulinase (EC 3.2.1.7); levanase (EC 3.2.1.65); exo- inulinase (EC 3.2.1.80); sucrose:sucrose 1- fructosyltransferase (EC 2.4.1.99); fructan:fructan 1- fructosyltransferase (EC 2.4.1.100); glycoside hydrolase family 32 protein 2598896 9794877 AARI_22860 Arthrobacter arilaitensis Re117 glycoside hydrolase family 32 protein YP_003917480.1 2597433 R 861360 CDS YP_003917481.1 308178075 9794879 complement(2599021..2599968) 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, peptide/opine/nickel uptake transporter (PepT) family (TC 3.A.1.5.z). ABCISSE: ABC transporter, ATP-binding protein (ABC), OPN-family (oligopeptides and nickel), oligopeptides import; dipeptide/oligopeptide ABC transporter ATP-binding subunit 2599968 9794879 AARI_22880 Arthrobacter arilaitensis Re117 dipeptide/oligopeptide ABC transporter ATP-binding subunit YP_003917481.1 2599021 R 861360 CDS YP_003917482.1 308178076 9794880 complement(2599965..2600882) 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, peptide/opine/nickel uptake transporter (PepT) family (TC 3.A.1.5.z). ABCISSE: ABC transporter, ATP-binding protein (ABC), OPN-family (oligopeptides and nickel), oligopeptides import; dipeptide/oligopeptide ABC transporter ATP-binding subunit 2600882 9794880 AARI_22890 Arthrobacter arilaitensis Re117 dipeptide/oligopeptide ABC transporter ATP-binding subunit YP_003917482.1 2599965 R 861360 CDS YP_003917483.1 308178077 9794881 complement(2600879..2601853) 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, peptide/opine/nickel uptake transporter (PepT) family (TC 3.A.1.5.z). ABCISSE: ABC transporter, permease (IM), OPN- family (oligopeptides and nickel), oligopeptides import; dipeptide/oligopeptide ABC transporter inner membrane subunit 2601853 9794881 AARI_22900 Arthrobacter arilaitensis Re117 dipeptide/oligopeptide ABC transporter inner membrane subunit YP_003917483.1 2600879 R 861360 CDS YP_003917484.1 308178078 9794882 complement(2601859..2602836) 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, peptide/opine/nickel uptake transporter (PepT) family (TC 3.A.1.5.z). ABCISSE: ABC transporter, permease (IM), OPN- family (oligopeptides and nickel), oligopeptides import; dipeptide/oligopeptide ABC transporter inner membrane subunit 2602836 9794882 AARI_22910 Arthrobacter arilaitensis Re117 dipeptide/oligopeptide ABC transporter inner membrane subunit YP_003917484.1 2601859 R 861360 CDS YP_003917485.1 308178079 9794883 complement(2602910..2604586) 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, peptide/opine/nickel uptake transporter (PepT) family (TC 3.A.1.5.z). ABCISSE: ABC transporter, binding protein (BP), OPN-family (oligopeptides and nickel), oligopeptides import; dipeptide/oligopeptide ABC transporter substrate-binding protein 2604586 9794883 AARI_22920 Arthrobacter arilaitensis Re117 dipeptide/oligopeptide ABC transporter substrate-binding protein YP_003917485.1 2602910 R 861360 CDS YP_003917486.1 308178080 9794884 complement(2604480..2605655) 1 NC_014550.1 match to protein domain PF00356. Numerous bacterial transcription regulatory proteins bind DNA via a helix- turn-helix (HTH) motif. These proteins are very diverse, but for convenience may be grouped into subfamilies on the basis of sequence similarity. One such family groups together a range of proteins, including ascG, ccpA, cytR, ebgR, fruR, galR, galS, lacI, malI, opnR, purF, rafR, rbtR and scrR. Within this family, the HTH motif is situated towards the N-terminus; LacI family transcriptional regulator 2605655 9794884 AARI_22930 Arthrobacter arilaitensis Re117 LacI family transcriptional regulator YP_003917486.1 2604480 R 861360 CDS YP_003917487.1 308178081 9794885 complement(2606026..2607054) 1 NC_014550.1 match to protein domain PF00356. Numerous bacterial transcription regulatory proteins bind DNA via a helix- turn-helix (HTH) motif. These proteins are very diverse, but for convenience may be grouped into subfamilies on the basis of sequence similarity. One such family groups together a range of proteins, including ascG, ccpA, cytR, ebgR, fruR, galR, galS, lacI, malI, opnR, purF, rafR, rbtR and scrR. Within this family, the HTH motif is situated towards the N-terminus; LacI family transcriptional regulator 2607054 9794885 AARI_22940 Arthrobacter arilaitensis Re117 LacI family transcriptional regulator YP_003917487.1 2606026 R 861360 CDS YP_003917488.1 308178082 9794886 2607177..2608649 1 NC_014550.1 glycoside hydrolase family 32 comprises enzymes with several known activities: invertase (EC 3.2.1.26); inulinase (EC 3.2.1.7); levanase (EC 3.2.1.65); exo- inulinase (EC 3.2.1.80); sucrose:sucrose 1- fructosyltransferase (EC 2.4.1.99); fructan:fructan 1- fructosyltransferase (EC 2.4.1.100); glycoside hydrolase family 32 protein 2608649 9794886 AARI_22950 Arthrobacter arilaitensis Re117 glycoside hydrolase family 32 protein YP_003917488.1 2607177 D 861360 CDS YP_003917489.1 308178083 9794887 2608646..2609551 1 NC_014550.1 fructokinase catalyzes the conversion of fructose to fructose-6-phosphate, which is an entry point into glycolysis via conversion into glucose-6-phosphate; fructokinase 2609551 9794887 AARI_22960 Arthrobacter arilaitensis Re117 fructokinase YP_003917489.1 2608646 D 861360 CDS YP_003917490.1 308178084 9794888 2609591..2610889 1 NC_014550.1 major facilitator superfamily, Oligosaccharide:H+ Symporter (OHS) Family (TC 2.A.1.5.z). Members of this family transport saccharides such as lactose, sucrose, raffinose and meliobiose; MFS superfamily sugar transporter 2610889 9794888 AARI_22970 Arthrobacter arilaitensis Re117 MFS superfamily sugar transporter YP_003917490.1 2609591 D 861360 CDS YP_003917491.1 308178085 9794891 2612413..2612895 1 NC_014550.1 hypothetical protein 2612895 9794891 AARI_23000 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917491.1 2612413 D 861360 CDS YP_003917492.1 308178086 9794892 2612930..2613124 1 NC_014550.1 hypothetical protein 2613124 9794892 AARI_23010 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917492.1 2612930 D 861360 CDS YP_003917493.1 308178087 9794893 complement(2613522..2614601) 1 NC_014550.1 hydrolyses O-sialoglycoproteins. Does not cleave unglycosylated proteins, desialylated glycoproteins or glycoproteins that are only N-glycosylated; O-sialoglycoprotein endopeptidase 2614601 gcp 9794893 gcp Arthrobacter arilaitensis Re117 O-sialoglycoprotein endopeptidase YP_003917493.1 2613522 R 861360 CDS YP_003917494.1 308178088 9793891 complement(2614598..2615089) 1 NC_014550.1 identified by match to PF00583: acetyltransferase (GNAT) family; GNAT family acetyltransferase 2615089 9793891 AARI_23030 Arthrobacter arilaitensis Re117 GNAT family acetyltransferase YP_003917494.1 2614598 R 861360 CDS YP_003917495.1 308178089 9794894 complement(2615086..2615763) 1 NC_014550.1 match to protein domain PF00814: glycoprotease family; glycoprotease 2615763 9794894 AARI_23040 Arthrobacter arilaitensis Re117 glycoprotease YP_003917495.1 2615086 R 861360 CDS YP_003917496.1 308178090 9794895 complement(2615756..2616334) 1 NC_014550.1 match to protein domain PF02367: uncharacterised P- loop hydrolase UPF0079. These proteins are probably essential to bacteria as members are found in all genomes so far sequenced and no equivalent genes have been found in the archaea and eukaryotes, suggesting a role in cell wall biosynthesis; ATP-binding protein 2616334 9794895 AARI_23050 Arthrobacter arilaitensis Re117 ATP-binding protein YP_003917496.1 2615756 R 861360 CDS YP_003917497.1 308178091 9794896 complement(2616327..2617526) 1 NC_014550.1 catalyzes the pyridoxal-dependent conversion of L- alanine into D-alanine, a key building block of bacterial peptidoglycan; alanine racemase 2617526 alr 9794896 alr Arthrobacter arilaitensis Re117 alanine racemase YP_003917497.1 2616327 R 861360 CDS YP_003917498.1 308178092 9793664 complement(2617673..2618044) 1 NC_014550.1 Large Conductance Mechanosensitive Ion Channel (MscL) Family (TC 1.A.22.1.z). This type of protein forms a nonselective ion channel; large conductance mechanosensitive channel protein 2618044 9793664 AARI_23070 Arthrobacter arilaitensis Re117 large conductance mechanosensitive channel protein YP_003917498.1 2617673 R 861360 CDS YP_003917499.1 308178093 9794897 complement(2618181..2619140) 1 NC_014550.1 catalyzes the phosphorylation of pantothenic acid to form 4-phosphopantothenic, which is the first of five steps in coenzyme A (CoA) biosynthetic pathway; pantothenate kinase 2619140 coaA 9794897 coaA Arthrobacter arilaitensis Re117 pantothenate kinase YP_003917499.1 2618181 R 861360 CDS YP_003917500.1 308178094 9793747 2619308..2621179 1 NC_014550.1 catalyses the formation of D-glucosamine 6- phosphate from D-fructose 6-phosphate. It is involved in the pathway for bacterial cell-wall peptidoglycan and lipopolysaccharide biosyntheses, being a step in the pathway for UDP-N-acetylglucosamine biosynthesis; glutamine--fructose-6-phosphate transaminase 2621179 glmS 9793747 glmS Arthrobacter arilaitensis Re117 glutamine--fructose-6-phosphate transaminase YP_003917500.1 2619308 D 861360 CDS YP_003917501.1 308178095 9793904 2621268..2621618 1 NC_014550.1 catalyses the following reaction: CoA-(4- phosphopantetheine) + apo-ACP => adenosine 3,5-bisphosphate + holo-ACP. All polyketide synthases, fatty-acid synthases and non- ribosomal peptide synthases require post-translational modification of their constituent ACP (ACP) domains to become catalytically active. The inactive apo-proteins are converted into their active holo-forms by transfer of the 4-phosphopantetheinyl moiety of CoA to the sidechain hydroxy group of a conserved serine residue in each ACP domain; holo-ACP synthase 2621618 acpS 9793904 acpS Arthrobacter arilaitensis Re117 holo-ACP synthase YP_003917501.1 2621268 D 861360 CDS YP_003917502.1 308178096 9793653 2621702..2623228 1 NC_014550.1 match to protein domain PF01256: carbohydrate kinase; hypothetical protein 2623228 9793653 AARI_23110 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917502.1 2621702 D 861360 CDS YP_003917503.1 308178097 9794898 complement(2623306..2624676) 1 NC_014550.1 catalyses the formation of UDP-glucuronate from UDP- glucose; UDP-glucose 6-dehydrogenase 2624676 9794898 AARI_23120 Arthrobacter arilaitensis Re117 UDP-glucose 6-dehydrogenase YP_003917503.1 2623306 R 861360 CDS YP_003917504.1 308178098 9794899 complement(2624826..2626172) 1 NC_014550.1 catalyses the formation of D-glucosamine 1- phosphate from D-glucosamine 6-phosphate. It is involved in the pathway for bacterial cell-wall peptidoglycan and lipopolysaccharide biosyntheses, being an essential step in the pathway for UDP-N-acetylglucosamine biosynthesis; phosphoglucosamine mutase 2626172 glmM 9794899 glmM Arthrobacter arilaitensis Re117 phosphoglucosamine mutase YP_003917504.1 2624826 R 861360 CDS YP_003917505.1 308178099 9793903 complement(2626343..2626843) 1 NC_014550.1 ribosomal protein S9 is one of the proteins from the small ribosomal subunit; 30S ribosomal protein S9 2626843 rpsI 9793903 rpsI Arthrobacter arilaitensis Re117 30S ribosomal protein S9 YP_003917505.1 2626343 R 861360 CDS YP_003917506.1 308178100 9794356 complement(2626882..2627325) 1 NC_014550.1 this protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly; 50S ribosomal protein L13 2627325 rplM 9794356 rplM Arthrobacter arilaitensis Re117 50S ribosomal protein L13 YP_003917506.1 2626882 R 861360 CDS YP_003917507.1 308178101 9794320 complement(2627651..2628586) 1 NC_014550.1 formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs; tRNA pseudouridylate synthase A 2628586 truA 9794320 truA Arthrobacter arilaitensis Re117 tRNA pseudouridylate synthase A YP_003917507.1 2627651 R 861360 CDS YP_003917508.1 308178102 9794476 2628841..2629281 1 NC_014550.1 signal peptide predicted by SignalP 3.0 HMM (probability: 0.999) with cleavage site probability 0.720 between position 29 and 30; hypothetical protein 2629281 9794476 AARI_23170 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917508.1 2628841 D 861360 CDS YP_003917509.1 308178103 9794900 2629589..2630029 1 NC_014550.1 signal peptide predicted by SignalP 3.0 HMM (probability: 0.999) with cleavage site probability 0.431 between position 29 and 30; hypothetical protein 2630029 9794900 AARI_23180 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917509.1 2629589 D 861360 CDS YP_003917510.1 308178104 9794901 2630042..2630158 1 NC_014550.1 hypothetical protein 2630158 9794901 AARI_23190 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917510.1 2630042 D 861360 CDS YP_003917511.1 308178105 9794902 complement(2630155..2630601) 1 NC_014550.1 part of the 50S ribosomal subunit. Contacts protein L32; 50S ribosomal protein L17 2630601 rplQ 9794902 rplQ Arthrobacter arilaitensis Re117 50S ribosomal protein L17 YP_003917511.1 2630155 R 861360 CDS YP_003917512.1 308178106 9794324 complement(2630685..2631686) 1 NC_014550.1 DNA-directed RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; DNA-directed RNA polymerase subunit alpha 2631686 rpoA 9794324 rpoA Arthrobacter arilaitensis Re117 DNA-directed RNA polymerase subunit alpha YP_003917512.1 2630685 R 861360 CDS YP_003917513.1 308178107 9794342 complement(2631857..2632258) 1 NC_014550.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; 30S ribosomal protein S11 2632258 rpsK 9794342 rpsK Arthrobacter arilaitensis Re117 30S ribosomal protein S11 YP_003917513.1 2631857 R 861360 CDS YP_003917514.1 308178108 9794358 complement(2632302..2632676) 1 NC_014550.1 part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome; 30S ribosomal protein S13 2632676 rpsM 9794358 rpsM Arthrobacter arilaitensis Re117 30S ribosomal protein S13 YP_003917514.1 2632302 R 861360 CDS YP_003917515.1 308178109 9794360 complement(2632825..2632938) 1 NC_014550.1 ribosomal protein L36 is the smallest protein from the large subunit of the prokaryotic ribosome; 50S ribosomal protein L36 2632938 rpmJ 9794360 rpmJ Arthrobacter arilaitensis Re117 50S ribosomal protein L36 YP_003917515.1 2632825 R 861360 CDS YP_003917516.1 308178110 9794341 complement(2633066..2633287) 1 NC_014550.1 translation initiation factor IF-1 2633287 infA 9794341 infA Arthrobacter arilaitensis Re117 translation initiation factor IF-1 YP_003917516.1 2633066 R 861360 CDS YP_003917517.1 308178111 9794008 complement(2633517..2634350) 1 NC_014550.1 responsible for the removal of the amino-terminal (initiator) methionine from nascent eukaryotic cytosolic and cytoplasmic prokaryotic proteins if the penultimate amino acid is small and uncharged; methionyl aminopeptidase 2634350 map 9794008 map Arthrobacter arilaitensis Re117 methionyl aminopeptidase YP_003917517.1 2633517 R 861360 CDS YP_003917518.1 308178112 9794060 complement(2634497..2635069) 1 NC_014550.1 catalyses the following reaction: ATP + AMP <=> 2 ADP; adenylate kinase 2635069 adk 9794060 adk Arthrobacter arilaitensis Re117 adenylate kinase YP_003917518.1 2634497 R 861360 CDS YP_003917519.1 308178113 9793659 complement(2635066..2636370) 1 NC_014550.1 identified by match to protein family PF00344. The translocase itself comprises 7 proteins, including a chaperone protein (SecB), an ATPase (SecA), an integral membrane complex (SecCY, SecE and SecG), and two additional membrane proteins that promote the release of the mature peptide into the periplasm (SecD and SecF); protein-export membrane protein SecY 2636370 secY 9793659 secY Arthrobacter arilaitensis Re117 protein-export membrane protein SecY YP_003917519.1 2635066 R 861360 CDS YP_003917520.1 308178114 9794391 complement(2636627..2637079) 1 NC_014550.1 binds to the 23S rRNA. Part of the 50S ribosomal subunit; 50S ribosomal protein L15 2637079 rplO 9794391 rplO Arthrobacter arilaitensis Re117 50S ribosomal protein L15 YP_003917520.1 2636627 R 861360 CDS YP_003917521.1 308178115 9794322 complement(2637082..2637288) 1 NC_014550.1 part of the 50S ribosomal subunit; 50S ribosomal protein L30 2637288 rpmD 9794322 rpmD Arthrobacter arilaitensis Re117 50S ribosomal protein L30 YP_003917521.1 2637082 R 861360 CDS YP_003917522.1 308178116 9794336 complement(2637292..2638002) 1 NC_014550.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; 30S ribosomal protein S5 2638002 rpsE 9794336 rpsE Arthrobacter arilaitensis Re117 30S ribosomal protein S5 YP_003917522.1 2637292 R 861360 CDS YP_003917523.1 308178117 9794352 complement(2637999..2638370) 1 NC_014550.1 part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs; 50S ribosomal protein L18 2638370 rplR 9794352 rplR Arthrobacter arilaitensis Re117 50S ribosomal protein L18 YP_003917523.1 2637999 R 861360 CDS YP_003917524.1 308178118 9794325 complement(2638373..2638909) 1 NC_014550.1 this protein binds to the 23S rRNA, and is important in its secondary structure. Part of the 50S ribosomal subunit; 50S ribosomal protein L6 2638909 rplF 9794325 rplF Arthrobacter arilaitensis Re117 50S ribosomal protein L6 YP_003917524.1 2638373 R 861360 CDS YP_003917525.1 308178119 9794315 complement(2638930..2639328) 1 NC_014550.1 one of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 2639328 rpsH 9794315 rpsH Arthrobacter arilaitensis Re117 30S ribosomal protein S8 YP_003917525.1 2638930 R 861360 CDS YP_003917526.1 308178120 9794355 complement(2639386..2639955) 1 NC_014550.1 part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA; 50S ribosomal protein L5 2639955 rplE 9794355 rplE Arthrobacter arilaitensis Re117 50S ribosomal protein L5 YP_003917526.1 2639386 R 861360 CDS YP_003917527.1 308178121 9794314 complement(2639955..2640299) 1 NC_014550.1 part of the 50S ribosomal subunit. One of two assembly inititator proteins, it binds directly to the 5 prime-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; 50S ribosomal protein L24 2640299 rplX 9794314 rplX Arthrobacter arilaitensis Re117 50S ribosomal protein L24 YP_003917527.1 2639955 R 861360 CDS YP_003917528.1 308178122 9794331 complement(2640302..2640673) 1 NC_014550.1 part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19; 50S ribosomal protein L14 2640673 rplN 9794331 rplN Arthrobacter arilaitensis Re117 50S ribosomal protein L14 YP_003917528.1 2640302 R 861360 CDS YP_003917529.1 308178123 9794321 2640959..2641120 1 NC_014550.1 hypothetical protein 2641120 9794321 AARI_23380 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917529.1 2640959 D 861360 CDS YP_003917530.1 308178124 9794903 complement(2641174..2642133) 1 NC_014550.1 match to PF03372: Endonuclease/Exonuclease/phosphatase family. This large family of proteins includes magnesium dependent endonucleases and a large number of phosphatases involved in intracellular signalling. Signal peptide predicted by SignalP 3.0 HMM (probability: 0.899) with cleavage site probability 0.551 between position 43 and 44; extracellular nuclease 2642133 9794903 AARI_23390 Arthrobacter arilaitensis Re117 extracellular nuclease YP_003917530.1 2641174 R 861360 CDS YP_003917531.1 308178125 9794904 complement(2642219..2642722) 1 NC_014550.1 identified by match to PF00903: glyoxalase/bleomycin resistance protein/dioxygenase superfamily; glyoxalase family protein 2642722 9794904 AARI_23400 Arthrobacter arilaitensis Re117 glyoxalase family protein YP_003917531.1 2642219 R 861360 CDS YP_003917532.1 308178126 9794905 2642793..2643581 1 NC_014550.1 identified by match to protein domain PF00165: bacterial regulatory helix-turn-helix proteins, AraC family; AraC family transcriptional regulator 2643581 9794905 AARI_23410 Arthrobacter arilaitensis Re117 AraC family transcriptional regulator YP_003917532.1 2642793 D 861360 CDS YP_003917533.1 308178127 9794907 complement(2644100..2644387) 1 NC_014550.1 one of the primary rRNA binding proteins, it binds specifically to the 5 prime-end of 16S ribosomal RNA; 30S ribosomal protein S17 2644387 rpsQ 9794907 rpsQ Arthrobacter arilaitensis Re117 30S ribosomal protein S17 YP_003917533.1 2644100 R 861360 CDS YP_003917534.1 308178128 9794364 complement(2644387..2644650) 1 NC_014550.1 ribosomal protein L29 is one of the proteins from the large ribosomal subunit; 50S ribosomal protein L29 2644650 rpmC 9794364 rpmC Arthrobacter arilaitensis Re117 50S ribosomal protein L29 YP_003917534.1 2644387 R 861360 CDS YP_003917535.1 308178129 9794335 complement(2644653..2645069) 1 NC_014550.1 part of the 50S ribosomal subunit. Cross-links to the A and P site tRNAs; 50S ribosomal protein L16 2645069 rplP 9794335 rplP Arthrobacter arilaitensis Re117 50S ribosomal protein L16 YP_003917535.1 2644653 R 861360 CDS YP_003917536.1 308178130 9794323 complement(2645070..2645852) 1 NC_014550.1 part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14; 30S ribosomal protein S3 2645852 rpsC 9794323 rpsC Arthrobacter arilaitensis Re117 30S ribosomal protein S3 YP_003917536.1 2645070 R 861360 CDS YP_003917537.1 308178131 9794350 complement(2645853..2646218) 1 NC_014550.1 this protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20; 50S ribosomal protein L22 2646218 rplV 9794350 rplV Arthrobacter arilaitensis Re117 50S ribosomal protein L22 YP_003917537.1 2645853 R 861360 CDS YP_003917538.1 308178132 9794329 complement(2646278..2646559) 1 NC_014550.1 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 2646559 rpsS 9794329 rpsS Arthrobacter arilaitensis Re117 30S ribosomal protein S19 YP_003917538.1 2646278 R 861360 CDS YP_003917539.1 308178133 9794366 complement(2646572..2647411) 1 NC_014550.1 part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome; 50S ribosomal protein L2 2647411 rplB 9794366 rplB Arthrobacter arilaitensis Re117 50S ribosomal protein L2 YP_003917539.1 2646572 R 861360 CDS YP_003917540.1 308178134 9794311 complement(2647443..2647745) 1 NC_014550.1 part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome; 50S ribosomal protein L23 2647745 rplW 9794311 rplW Arthrobacter arilaitensis Re117 50S ribosomal protein L23 YP_003917540.1 2647443 R 861360 CDS YP_003917541.1 308178135 9794330 complement(2647742..2648344) 1 NC_014550.1 one of the primary rRNA binding proteins. It is important during the early stages of 50S assembly; 50S ribosomal protein L4 2648344 rplD 9794330 rplD Arthrobacter arilaitensis Re117 50S ribosomal protein L4 YP_003917541.1 2647742 R 861360 CDS YP_003917542.1 308178136 9794313 complement(2648349..2648999) 1 NC_014550.1 part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19; 50S ribosomal protein L3 2648999 rplC 9794313 rplC Arthrobacter arilaitensis Re117 50S ribosomal protein L3 YP_003917542.1 2648349 R 861360 CDS YP_003917543.1 308178137 9794312 complement(2649020..2649328) 1 NC_014550.1 involved in the binding of tRNA to the ribosomes; 30S ribosomal protein S10 2649328 rpsJ 9794312 rpsJ Arthrobacter arilaitensis Re117 30S ribosomal protein S10 YP_003917543.1 2649020 R 861360 CDS YP_003917544.1 308178138 9794357 complement(2649735..2653502) 1 NC_014550.1 37 transmembrane helices predicted by TMHMM2.0; hypothetical protein 2653502 9794357 AARI_23540 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917544.1 2649735 R 861360 CDS YP_003917545.1 308178139 9794908 complement(2653665..2654855) 1 NC_014550.1 responsible for the selection and binding of the cognate aminoacyl-tRNA to the A-site (acceptor site) of the ribosome; elongation factor Tu 2654855 tuf 9794908 tuf Arthrobacter arilaitensis Re117 elongation factor Tu YP_003917545.1 2653665 R 861360 CDS YP_003917546.1 308178140 9794483 complement(2655098..2657212) 1 NC_014550.1 responsible for the translocation of the peptidyl- tRNA from the A-site to the P-site (peptidyl-tRNA site) of the ribosome, thereby freeing the A-site for the next aminoacyl-tRNA to bind; elongation factor G 2657212 fusA 9794483 fusA Arthrobacter arilaitensis Re117 elongation factor G YP_003917546.1 2655098 R 861360 CDS YP_003917547.1 308178141 9793874 complement(2657282..2657752) 1 NC_014550.1 part of the 30S ribosomal subunit. Contacts proteins S9 and S11; 30S ribosomal protein S7 2657752 rpsG 9793874 rpsG Arthrobacter arilaitensis Re117 30S ribosomal protein S7 YP_003917547.1 2657282 R 861360 CDS YP_003917548.1 308178142 9794354 complement(2657752..2658126) 1 NC_014550.1 part of the 30S ribosomal subunit. Contacts proteins S8 and S17; 30S ribosomal protein S12 2658126 rpsL 9794354 rpsL Arthrobacter arilaitensis Re117 30S ribosomal protein S12 YP_003917548.1 2657752 R 861360 CDS YP_003917549.1 308178143 9794359 complement(2658728..2662618) 1 NC_014550.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; DNA-directed RNA polymerase beta prime chain 2662618 rpoC 9794359 rpoC Arthrobacter arilaitensis Re117 DNA-directed RNA polymerase beta prime chain YP_003917549.1 2658728 R 861360 CDS YP_003917550.1 308178144 9794344 complement(2662717..2666223) 1 NC_014550.1 DNA-directed RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; DNA-directed RNA polymerase subunit beta 2666223 rpoB 9794344 rpoB Arthrobacter arilaitensis Re117 DNA-directed RNA polymerase subunit beta YP_003917550.1 2662717 R 861360 CDS YP_003917551.1 308178145 9794343 2666835..2667332 1 NC_014550.1 match to PF04073: YbaK / prolyl-tRNA synthetases associated domain. This domain of unknown function is found in numerous prokaryote organisms. The structure of YbaK shows a novel fold. This domain also occurs in a number of prolyl-tRNA synthetases (proRS) from prokaryotes. Thus, the domain is thought to be involved in oligo-nucleotide binding, with possible roles in recognition/discrimination or editing of prolyl-tRNA; YbaK domain-containing protein 2667332 9794343 AARI_23610 Arthrobacter arilaitensis Re117 YbaK domain-containing protein YP_003917551.1 2666835 D 861360 CDS YP_003917552.1 308178146 9794909 complement(2667286..2668455) 1 NC_014550.1 match to protein domain PF01757. This family includes a range of acyltransferase enzymes. 10 transmembrane helices predicted by TMHMM2.0; acyltransferase domain-containing membrane protein 2668455 9794909 AARI_23620 Arthrobacter arilaitensis Re117 acyltransferase domain-containing membrane protein YP_003917552.1 2667286 R 861360 CDS YP_003917553.1 308178147 9794910 complement(2668602..2668976) 1 NC_014550.1 seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation; 50S ribosomal protein L7/L12 2668976 rplL 9794910 rplL Arthrobacter arilaitensis Re117 50S ribosomal protein L7/L12 YP_003917553.1 2668602 R 861360 CDS YP_003917554.1 308178148 9794319 complement(2669050..2669571) 1 NC_014550.1 50S ribosomal protein L10 2669571 rplJ 9794319 rplJ Arthrobacter arilaitensis Re117 50S ribosomal protein L10 YP_003917554.1 2669050 R 861360 CDS YP_003917555.1 308178149 9794317 complement(2670127..2670828) 1 NC_014550.1 part of the 50S ribosomal subunit. Binds directly to 23S rRNA. Is involved in E site tRNA release and is also a translational repressor protein: it controls the translation of the L11 operon by binding to its mRNA; 50S ribosomal protein L1 2670828 rplA 9794317 rplA Arthrobacter arilaitensis Re117 50S ribosomal protein L1 YP_003917555.1 2670127 R 861360 CDS YP_003917556.1 308178150 9794310 complement(2670964..2671395) 1 NC_014550.1 this protein binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 2671395 rplK 9794310 rplK Arthrobacter arilaitensis Re117 50S ribosomal protein L11 YP_003917556.1 2670964 R 861360 CDS YP_003917557.1 308178151 9794318 complement(2671525..2672352) 1 NC_014550.1 influences transcription termination and antitermination. Acts as a component of the transcription complex, and interacts with the termination factor rho and RNA polymerase; transcription antitermination protein NusG 2672352 nusG 9794318 nusG Arthrobacter arilaitensis Re117 transcription antitermination protein NusG YP_003917557.1 2671525 R 861360 CDS YP_003917558.1 308178152 9794155 complement(2672425..2672673) 1 NC_014550.1 identified by match to protein family PF00584. The translocase itself comprises 7 proteins, including a chaperone protein (SecB), an ATPase (SecA), an integral membrane complex (SecCY, SecE and SecG), and two additional membrane proteins that promote the release of the mature peptide into the periplasm (SecD and SecF); preprotein translocase SecE subunit 2672673 secE 9794155 secE Arthrobacter arilaitensis Re117 preprotein translocase SecE subunit YP_003917558.1 2672425 R 861360 CDS YP_003917559.1 308178153 9793638 2673129..2674328 1 NC_014550.1 catalyses the following reaction: L-aspartate + 2- oxoglutarate <=> oxaloacetate + L-glutamate; aspartate transaminase 2674328 aspC 9793638 aspC Arthrobacter arilaitensis Re117 aspartate transaminase YP_003917559.1 2673129 D 861360 CDS YP_003917560.1 308178154 9793697 complement(2674405..2675073) 1 NC_014550.1 response regulators are key elements in two- component signal transduction systems, which enable bacteria to sense, respond, and adapt to a wide range of environments, stressors, and growth conditions; two-component system response regulator 2675073 9793697 AARI_23700 Arthrobacter arilaitensis Re117 two-component system response regulator YP_003917560.1 2674405 R 861360 CDS YP_003917561.1 308178155 9794911 complement(2675078..2676307) 1 NC_014550.1 protein-histidine kinases are key elements in two- component signal transduction systems, which enable bacteria to sense, respond, and adapt to a wide range of environments, stressors, and growth conditions; signal transduction histidine kinase 2676307 9794911 AARI_23710 Arthrobacter arilaitensis Re117 signal transduction histidine kinase YP_003917561.1 2675078 R 861360 CDS YP_003917562.1 308178156 9794912 2676458..2677777 1 NC_014550.1 identified by match to protein domain PF04024. This domain is found in Phage shock protein C (PspC) that is thought to be a transcriptional regulator; PspC domain-containing protein 2677777 9794912 AARI_23720 Arthrobacter arilaitensis Re117 PspC domain-containing protein YP_003917562.1 2676458 D 861360 CDS YP_003917563.1 308178157 9794913 2677790..2678038 1 NC_014550.1 hypothetical protein 2678038 9794913 AARI_23730 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917563.1 2677790 D 861360 CDS YP_003917564.1 308178158 9794914 2678073..2678315 1 NC_014550.1 identified by match to protein domain PF04024. This domain is found in Phage shock protein C (PspC) that is thought to be a transcriptional regulator; PspC domain-containing protein 2678315 9794914 AARI_23740 Arthrobacter arilaitensis Re117 PspC domain-containing protein YP_003917564.1 2678073 D 861360 CDS YP_003917565.1 308178159 9794915 2678572..2679600 1 NC_014550.1 catalyzes the phosphorylation of fructose-6- phosphate to fructose-1,6-biphosphate; 6-phosphofructokinase 2679600 pfkA 9794915 pfkA Arthrobacter arilaitensis Re117 6-phosphofructokinase YP_003917565.1 2678572 D 861360 CDS YP_003917566.1 308178160 9794196 complement(2679675..2680757) 1 NC_014550.1 aminomethyltransferase 2680757 9794196 AARI_23760 Arthrobacter arilaitensis Re117 aminomethyltransferase YP_003917566.1 2679675 R 861360 CDS YP_003917567.1 308178161 9794916 complement(2680760..2681374) 1 NC_014550.1 match to PF08768: domain of unknown function (DUF1794); hypothetical protein 2681374 9794916 AARI_23770 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917567.1 2680760 R 861360 CDS YP_003917568.1 308178162 9794917 complement(2681445..2681564) 1 NC_014550.1 hypothetical protein 2681564 9794917 AARI_23780 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917568.1 2681445 R 861360 CDS YP_003917569.1 308178163 9794918 complement(2681642..2682382) 1 NC_014550.1 signal peptide predicted by SignalP 3.0 HMM (probability: 0.998) with cleavage site probability 0.386 between position 19 and 20. 8 transmembrane helices predicted by TMHMM2.0 after the signal peptide; hypothetical protein 2682382 9794918 AARI_23790 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917569.1 2681642 R 861360 CDS YP_003917570.1 308178164 9794919 2682509..2683177 1 NC_014550.1 response regulators are key elements in two- component signal transduction systems, which enable bacteria to sense, respond, and adapt to a wide range of environments, stressors, and growth conditions; two-component system response regulator 2683177 9794919 AARI_23800 Arthrobacter arilaitensis Re117 two-component system response regulator YP_003917570.1 2682509 D 861360 CDS YP_003917571.1 308178165 9794920 2683230..2684186 1 NC_014550.1 identified by match to PF00583: acetyltransferase (GNAT) family; GNAT family acetyltransferase 2684186 9794920 AARI_23810 Arthrobacter arilaitensis Re117 GNAT family acetyltransferase YP_003917571.1 2683230 D 861360 CDS YP_003917572.1 308178166 9794921 2684269..2686485 1 NC_014550.1 catalyzes the following reaction: ATP + (phosphate)(n) <=> ADP + (phosphate)(n+1). involved in phosphate metabolism of bacteria; polyphosphate kinase 2686485 ppk 9794921 ppk Arthrobacter arilaitensis Re117 polyphosphate kinase YP_003917572.1 2684269 D 861360 CDS YP_003917573.1 308178167 9794218 2686485..2687492 1 NC_014550.1 identified by match to PF00293. Members of the Nudix hydrolase superfamily catalyze the hydrolysis of nucleoside diphosphates linked to other moieties. Substrates of nudix hydrolases include intact and oxidatively damaged nucleoside triphosphates, dinucleoside polyphosphates, nucleotide-sugars and dinucleotide enzymes. These substrates are metabolites or cell signaling molecules that require regulation during different stages of the cell cycle or during periods of stress. In general, the role of the nudix hydrolase is to sanitize the nucleotide pools and to maintain cell viability, thereby serving as surveillance and house- cleaning enzymes; NUDIX hydrolase 2687492 9794218 AARI_23830 Arthrobacter arilaitensis Re117 NUDIX hydrolase YP_003917573.1 2686485 D 861360 CDS YP_003917574.1 308178168 9794922 2687632..2687964 1 NC_014550.1 identified by match to PF00583: acetyltransferase (GNAT) family; GNAT family acetyltransferase 2687964 9794922 AARI_23840 Arthrobacter arilaitensis Re117 GNAT family acetyltransferase YP_003917574.1 2687632 D 861360 CDS YP_003917575.1 308178169 9794923 2688039..2688842 1 NC_014550.1 catalyzes the reductive methylation of dUMP to dTMP with concomitant conversion of 5,10- methylenetetrahydrofolate to dihydrofolate; thymidylate synthase 2688842 thyA 9794923 thyA Arthrobacter arilaitensis Re117 thymidylate synthase YP_003917575.1 2688039 D 861360 CDS YP_003917576.1 308178170 9794452 2688839..2689414 1 NC_014550.1 catalyzes the NADPH-linked reduction of 7,8- dihydrofolate to 5,6,7,8-tetrahydrofolate, but also the NADPH-linked reduction of folate to 7,8-dihydrofolate; dihydrofolate reductase 2689414 folA 9794452 folA Arthrobacter arilaitensis Re117 dihydrofolate reductase YP_003917576.1 2688839 D 861360 CDS YP_003917577.1 308178171 9793856 2689422..2689649 1 NC_014550.1 2 transmembrane helices predicted by TMHMM2.0; hypothetical protein 2689649 9793856 AARI_23870 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917577.1 2689422 D 861360 CDS YP_003917578.1 308178172 9794924 2689798..2690880 1 NC_014550.1 catalyzes the NADP-dependent reductive dephosphorylation of L-aspartyl phosphate to L-aspartate- semialdehyde. Second step in the common biosynthetic pathway leading from aspartate to diaminopimelate and lysine, to methionine, and to threonine; aspartate-semialdehyde dehydrogenase 2690880 asd 9794924 asd Arthrobacter arilaitensis Re117 aspartate-semialdehyde dehydrogenase YP_003917578.1 2689798 D 861360 CDS YP_003917579.1 308178173 9793693 complement(2690975..2691499) 1 NC_014550.1 identified by match to PF00583: acetyltransferase (GNAT) family; GNAT family acetyltransferase 2691499 9793693 AARI_23890 Arthrobacter arilaitensis Re117 GNAT family acetyltransferase YP_003917579.1 2690975 R 861360 CDS YP_003917580.1 308178174 9794925 complement(2691519..2692580) 1 NC_014550.1 catalyses the formation of UDP-N-acetylmuramate from UDP-N-acetyl-3-O-(1-carboxyvinyl)-D-glucosamine. Involved in the biosynthesis of peptidoglycan; UDP-N-acetylmuramate dehydrogenase 2692580 murB 9794925 murB Arthrobacter arilaitensis Re117 UDP-N-acetylmuramate dehydrogenase YP_003917580.1 2691519 R 861360 CDS YP_003917581.1 308178175 9794117 complement(2692634..2693833) 1 NC_014550.1 major facilitator superfamily (TC 2.A.1.y.z). Identified by match to protein family PF07690; MFS superfamily transporter 2693833 9794117 AARI_23910 Arthrobacter arilaitensis Re117 MFS superfamily transporter YP_003917581.1 2692634 R 861360 CDS YP_003917582.1 308178176 9794926 complement(2693836..2694276) 1 NC_014550.1 match to PF01575. Several bacterial proteins that are composed solely of this domain have (R)-specific enoyl- CoA hydratase activity; MaoC like domain-containing protein 2694276 9794926 AARI_23920 Arthrobacter arilaitensis Re117 MaoC like domain-containing protein YP_003917582.1 2693836 R 861360 CDS YP_003917583.1 308178177 9794927 complement(2694279..2694725) 1 NC_014550.1 match to PF01575. Several bacterial proteins that are composed solely of this domain have (R)-specific enoyl- CoA hydratase activity; MaoC like domain-containing protein 2694725 9794927 AARI_23930 Arthrobacter arilaitensis Re117 MaoC like domain-containing protein YP_003917583.1 2694279 R 861360 CDS YP_003917584.1 308178178 9794928 complement(2694824..2695099) 1 NC_014550.1 2 transmembrane helices predicted by TMHMM2.0; hypothetical protein 2695099 9794928 AARI_23940 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917584.1 2694824 R 861360 CDS YP_003917585.1 308178179 9794929 complement(2695199..2696140) 1 NC_014550.1 hypothetical protein 2696140 9794929 AARI_23950 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917585.1 2695199 R 861360 CDS YP_003917586.1 308178180 9794930 2696335..2697153 1 NC_014550.1 match to PF04607. This region of unknown function is found in RelA and SpoT of Escherichia coli, and their homologues in plants and in other eubacteria; RelA/SpoT domain-containing protein 2697153 9794930 AARI_23960 Arthrobacter arilaitensis Re117 RelA/SpoT domain-containing protein YP_003917586.1 2696335 D 861360 CDS YP_003917587.1 308178181 9794931 2697418..2697675 1 NC_014550.1 signal peptide predicted by SignalP 3.0 HMM (probability: 0.976) with cleavage site probability 0.739 between position 24 and 25; hypothetical protein 2697675 9794931 AARI_23970 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917587.1 2697418 D 861360 CDS YP_003917588.1 308178182 9793641 2698928..2700670 1 NC_014550.1 required for the synthesis of the hydromethylpyrimidine (HMP) moiety of thiamine (4-amino-2- methyl-5-hydroxymethylpyrimidine); thiamine biosynthesis protein ThiC 2700670 thiC 9793641 thiC Arthrobacter arilaitensis Re117 thiamine biosynthesis protein ThiC YP_003917588.1 2698928 D 861360 CDS YP_003917589.1 308178183 9794439 complement(2700764..2702692) 1 NC_014550.1 DEAD box helicase. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression; ATP-dependent RNA helicase 2702692 9794439 AARI_23990 Arthrobacter arilaitensis Re117 ATP-dependent RNA helicase YP_003917589.1 2700764 R 861360 CDS YP_003917590.1 308178184 9794933 2702989..2703405 1 NC_014550.1 3 transmembrane helices predicted by TMHMM2.0; hypothetical protein 2703405 9794933 AARI_24000 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917590.1 2702989 D 861360 CDS YP_003917591.1 308178185 9794934 complement(2703504..2704661) 1 NC_014550.1 catalyzes the conversion of cysteine and succinyl- homoserine into cystathionine and succinate. Several other reactions may also be catalysed in some organisms; cystathionine gamma-synthase 2704661 metB 9794934 metB Arthrobacter arilaitensis Re117 cystathionine gamma-synthase YP_003917591.1 2703504 R 861360 CDS YP_003917592.1 308178186 9794069 complement(2704689..2706053) 1 NC_014550.1 catalyses the synthesis of L-cystathionine from L- serine and L-homocysteine; cystathionine beta-synthase 2706053 9794069 AARI_24020 Arthrobacter arilaitensis Re117 cystathionine beta-synthase YP_003917592.1 2704689 R 861360 CDS YP_003917593.1 308178187 9794935 2706193..2707155 1 NC_014550.1 hypothetical protein 2707155 9794935 AARI_24030 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917593.1 2706193 D 861360 CDS YP_003917594.1 308178188 9794936 complement(2707180..2707554) 1 NC_014550.1 serves as a general protein disulphide oxidoreductase. It interacts with a broad range of proteins by a redox mechanism based on reversible oxidation of 2 cysteine thiol groups to a disulphide, accompanied by the transfer of 2 electrons and 2 protons. The net result is the covalent interconversion of a disulphide and a dithiol; thioredoxin 2707554 trx 9794936 trx Arthrobacter arilaitensis Re117 thioredoxin YP_003917594.1 2707180 R 861360 CDS YP_003917595.1 308178189 9793642 complement(2707918..2709225) 1 NC_014550.1 transposase of ISAar20, ISL3 family 2709225 9793642 AARI_35600 Arthrobacter arilaitensis Re117 transposase of ISAar20, ISL3 family YP_003917595.1 2707918 R 861360 CDS YP_003917596.1 308178190 9793501 2709417..2709905 1 NC_014550.1 match to protein family PF04461: protein of unknown function (DUF520); hypothetical protein 2709905 9793501 AARI_24050 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917596.1 2709417 D 861360 CDS YP_003917597.1 308178191 9794937 complement(2710011..2710607) 1 NC_014550.1 4 transmembrane helices predicted by TMHMM2.0; hypothetical protein 2710607 9794937 AARI_24060 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917597.1 2710011 R 861360 CDS YP_003917598.1 308178192 9794938 complement(2710833..2711705) 1 NC_014550.1 in Escherichia coli, HtpX is a membrane- bound zinc metalloprotease that has been suggested to participate in the proteolytic quality control of membrane proteins in conjunction with FtsH, a membrane-bound and ATP-dependent protease. 6 transmembrane helices predicted by TMHMM2.0. Match to protein family PF01435; protease HtpX-like protein 2711705 htpX 9794938 htpX Arthrobacter arilaitensis Re117 protease HtpX-like protein YP_003917598.1 2710833 R 861360 CDS YP_003917599.1 308178193 9793987 2711945..2712883 1 NC_014550.1 drug/metabolite transporter (DMT) superfamily, chloramphenicol-sensitivity protein (RarD) family (TC 2.A. 7.7.z). No member of the RarD family is functionally characterized. Identified by match to TIGR00688; RarD protein 2712883 rarD 9793987 rarD Arthrobacter arilaitensis Re117 RarD protein YP_003917599.1 2711945 D 861360 CDS YP_003917600.1 308178194 9794282 complement(2712981..2714324) 1 NC_014550.1 catalyzes the transfer of an amino group from GABA to alpha-ketoglutarate, yielding succinate semialdehyde and glutamic acid; 4-aminobutyrate transaminase 2714324 gabT 9794282 gabT Arthrobacter arilaitensis Re117 4-aminobutyrate transaminase YP_003917600.1 2712981 R 861360 CDS YP_003917601.1 308178195 9793878 complement(2714529..2714672) 1 NC_014550.1 hypothetical protein 2714672 9793878 AARI_24100 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917601.1 2714529 R 861360 CDS YP_003917602.1 308178196 9794939 complement(2714675..2716282) 1 NC_014550.1 Neurotransmitter:Sodium Symporter (NSS) Family (Tc 2.A.22.y.z). Members of the NSS family catalyze uptake of a variety of neurotransmitters, amino acids, osmolytes and related nitrogenous substances by a solute:Na+ symport mechanism. Sometimes Cl- is cotransported, and some exhibit a K+ dependency. Might be involved in the transport of gamma-aminobutyric acid; sodium-dependent transporter 2716282 9794939 AARI_24110 Arthrobacter arilaitensis Re117 sodium-dependent transporter YP_003917602.1 2714675 R 861360 CDS YP_003917603.1 308178197 9794940 2716396..2717799 1 NC_014550.1 match to PF07905: purine catabolism regulatory protein-like family. The bacterial proteins found in this family are similar to the purine catabolism regulatory protein expressed by Bacillus subtilis (PucR, O32138). PucR is thought to be a transcriptional activator involved in the induction of the purine degradation pathway, and may contain a LysR-like DNA-binding domain. It is similar to LysR-type regulators in that it represses its own expression. The other members of this family are also annotated as being regulatory proteins; transcriptional regulator 2717799 9794940 AARI_24120 Arthrobacter arilaitensis Re117 transcriptional regulator YP_003917603.1 2716396 D 861360 CDS YP_003917604.1 308178198 9794941 2717818..2718252 1 NC_014550.1 hypothetical protein 2718252 9794941 AARI_24130 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917604.1 2717818 D 861360 CDS YP_003917605.1 308178199 9794942 2718252..2718764 1 NC_014550.1 match to protein family IPR001310: histidine triad (HIT) protein. The histidine triad motif (HIT) is related to the sequence H-phi-H-phi-H-phi-phi (where phi is a hydrophobic amino acid). Proteins containing HIT domains form a superfamily of nucleotide hydrolases and transferases that act on the alpha-phosphate of ribonucleotides; histidine triad family protein 2718764 9794942 AARI_24140 Arthrobacter arilaitensis Re117 histidine triad family protein YP_003917605.1 2718252 D 861360 CDS YP_003917606.1 308178200 9794943 complement(2718840..2719937) 1 NC_014550.1 produces prenyl diphosphates which act as the priming substrates for other groups of prenyl transferases. Is implicated in the biosynthesis of ubiquinone; trans-hexaprenyltranstransferase 2719937 9794943 AARI_24150 Arthrobacter arilaitensis Re117 trans-hexaprenyltranstransferase YP_003917606.1 2718840 R 861360 CDS YP_003917607.1 308178201 9794944 2720229..2721566 1 NC_014550.1 catalyses the conversion of chorismate to isochorismate, the first step in the biosynthesis of both the respiratory chain component menaquinone (MK, vitamin K2) and phylloquinone (vitamin K1): Chorismate <=> isochorismate; isochorismate synthase 2721566 menF 9794944 menF Arthrobacter arilaitensis Re117 isochorismate synthase YP_003917607.1 2720229 D 861360 CDS YP_003917608.1 308178202 9794066 2721740..2722528 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, polar amino acid uptake transporter (PAAT) family (TC 3.A.1.3.z). ABCISSE: ABC transporter, binding protein (BP), PAO-family (polar amino acid and opines). The PAO family includes transport systems for amino acids that have polar or charged side chains: lysine, histidine, ornithine, arginine, glutamine, glutamate, cystine and diaminopimelic acid; polar amino acid ABC transporter substrate-binding protein 2722528 9794066 AARI_24170 Arthrobacter arilaitensis Re117 polar amino acid ABC transporter substrate-binding protein YP_003917608.1 2721740 D 861360 CDS YP_003917609.1 308178203 9794945 2722640..2723431 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, polar amino acid uptake transporter (PAAT) family (TC 3.A.1.3.z). ABCISSE: ABC transporter, permease (IM), PAO- family (polar amino acid and opines). The PAO family includes transport systems for amino acids that have polar or charged side chains: lysine, histidine, ornithine, arginine, glutamine, glutamate, cystine and diaminopimelic acid; polar amino acid ABC transporter inner membrane subunit 2723431 9794945 AARI_24180 Arthrobacter arilaitensis Re117 polar amino acid ABC transporter inner membrane subunit YP_003917609.1 2722640 D 861360 CDS YP_003917610.1 308178204 9794946 2723446..2724228 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, polar amino acid uptake transporter (PAAT) family (TC 3.A.1.3.z). ABCISSE: ABC transporter, ATP-binding protein (ABC), PAO-family (polar amino acid and opines). The PAO family includes transport systems for amino acids that have polar or charged side chains: lysine, histidine, ornithine, arginine, glutamine, glutamate, cystine and diaminopimelic acid; polar amino acid ABC transporter ATP-binding subunit 2724228 9794946 AARI_24190 Arthrobacter arilaitensis Re117 polar amino acid ABC transporter ATP-binding subunit YP_003917610.1 2723446 D 861360 CDS YP_003917611.1 308178205 9794947 complement(2724300..2725997) 1 NC_014550.1 EC 2.2.1.9 plays a key role in the menaquinone biosynthetic pathway, converting isochorismate and 2- oxoglutarate to SHCHC (2-succinyl-6-hydroxyl-2,4- cyclohexadiene-1-carboxylic acid), pyruvate and carbon dioxide; bifunctional 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase/2-oxoglutarate decarboxylase 2725997 menD 9794947 menD Arthrobacter arilaitensis Re117 bifunctional 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase/2-oxoglutarate decarboxylase YP_003917611.1 2724300 R 861360 CDS YP_003917612.1 308178206 9794064 complement(2726148..2728271) 1 NC_014550.1 match to PS00583 pattern: PTS HPR domain serine phosphorylation site; hypothetical protein 2728271 9794064 AARI_24210 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917612.1 2726148 R 861360 CDS YP_003917613.1 308178207 9794948 complement(2728397..2729392) 1 NC_014550.1 catalyzes the conversion of 2-succinyl-6-hydroxy- 2, 4-cyclohexadiene-1-carboxylate (SHCHC) to 4-(2- carboxyphenyl)-4-oxobutyrate (o-succinylbenzoate or OSB), a reaction in the menaquinone biosynthetic pathway; O-succinylbenzoate synthase 2729392 menC 9794948 menC Arthrobacter arilaitensis Re117 O-succinylbenzoate synthase YP_003917613.1 2728397 R 861360 CDS YP_003917614.1 308178208 9794063 2729473..2730336 1 NC_014550.1 PAP2 family protein 2730336 9794063 AARI_24230 Arthrobacter arilaitensis Re117 PAP2 family protein YP_003917614.1 2729473 D 861360 CDS YP_003917615.1 308178209 9794949 complement(2730364..2731395) 1 NC_014550.1 6 transmembrane helices predicted by TMHMM2.0; hypothetical protein 2731395 9794949 AARI_24240 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917615.1 2730364 R 861360 CDS YP_003917616.1 308178210 9794950 complement(2731631..2733040) 1 NC_014550.1 possible component of pyruvate dehydrogenase (EC 2. 3.1.12), branched-chain alpha-ketoacid dehydrogenase (EC 2. 3.1.168) or 2-oxoglutarate dehydrogenase (EC 2.3.1.61) complexes; 2-oxoacid dehydrogenase E2 component 2733040 9794950 AARI_24250 Arthrobacter arilaitensis Re117 2-oxoacid dehydrogenase E2 component YP_003917616.1 2731631 R 861360 CDS YP_003917617.1 308178211 9794951 complement(2733041..2734123) 1 NC_014550.1 possible component of pyruvate dehydrogenase (EC 2. 3.1.12), branched-chain alpha-ketoacid dehydrogenase (EC 2. 3.1.168) or 2-oxoglutarate dehydrogenase (EC 2.3.1.61) complexes; 2-oxoacid dehydrogenase E1 component subunit beta 2734123 9794951 AARI_24260 Arthrobacter arilaitensis Re117 2-oxoacid dehydrogenase E1 component subunit beta YP_003917617.1 2733041 R 861360 CDS YP_003917618.1 308178212 9794952 complement(2734125..2735288) 1 NC_014550.1 possible component of pyruvate dehydrogenase (EC 2. 3.1.12), branched-chain alpha-ketoacid dehydrogenase (EC 2. 3.1.168) or 2-oxoglutarate dehydrogenase (EC 2.3.1.61) complexes; 2-oxoacid dehydrogenase E1 component subunit alpha 2735288 9794952 AARI_24270 Arthrobacter arilaitensis Re117 2-oxoacid dehydrogenase E1 component subunit alpha YP_003917618.1 2734125 R 861360 CDS YP_003917619.1 308178213 9794953 2735515..2735967 1 NC_014550.1 identified by match to protein family PF01037; AsnC/Lrp family transcriptional regulator 2735967 9794953 AARI_24280 Arthrobacter arilaitensis Re117 AsnC/Lrp family transcriptional regulator YP_003917619.1 2735515 D 861360 CDS YP_003917620.1 308178214 9794954 complement(2736043..2736828) 1 NC_014550.1 involved in aromatic ring opening step of the phenylacetic acid catabolic pathway; phenylacetic acid degradation protein PaaB 2736828 paaB 9794954 paaB Arthrobacter arilaitensis Re117 phenylacetic acid degradation protein PaaB YP_003917620.1 2736043 R 861360 CDS YP_003917621.1 308178215 9794163 complement(2736847..2738007) 1 NC_014550.1 phenylacetate-CoA oxygenase is comprised of a five gene complex responsible for the hydroxylation of phenylacetate-CoA as the second catabolic step in phenylacetic acid degradation. Although the exact function of this enzyme has not been determined, it has been shown to be required for phenylacetic acid degradation and has been proposed to function in a multicomponent oxygenase acting on phenylacetate-CoA; phenylacetate-CoA oxygenase subunit PaaK 2738007 paaK 9794163 paaK Arthrobacter arilaitensis Re117 phenylacetate-CoA oxygenase subunit PaaK YP_003917621.1 2736847 R 861360 CDS YP_003917622.1 308178216 9794170 complement(2738004..2738501) 1 NC_014550.1 phenylacetate-CoA oxygenase is comprised of a five gene complex responsible for the hydroxylation of phenylacetate-CoA as the second catabolic step in phenylacetic acid degradation. Although the exact function of this enzyme has not been determined, it has been shown to be required for phenylacetic acid degradation and has been proposed to function in a multicomponent oxygenase acting on phenylacetate-CoA; phenylacetate-CoA oxygenase subunit PaaJ 2738501 paaJ 9794170 paaJ Arthrobacter arilaitensis Re117 phenylacetate-CoA oxygenase subunit PaaJ YP_003917622.1 2738004 R 861360 CDS YP_003917623.1 308178217 9794169 complement(2738537..2739397) 1 NC_014550.1 phenylacetate-CoA oxygenase is comprised of a five gene complex responsible for the hydroxylation of phenylacetate-CoA as the second catabolic step in phenylacetic acid degradation. Although the exact function of this enzyme has not been determined, it has been shown to be required for phenylacetic acid degradation and has been proposed to function in a multicomponent oxygenase acting on phenylacetate-CoA; phenylacetate-CoA oxygenase subunit PaaI 2739397 paaI 9794169 paaI Arthrobacter arilaitensis Re117 phenylacetate-CoA oxygenase subunit PaaI YP_003917623.1 2738537 R 861360 CDS YP_003917624.1 308178218 9794168 complement(2739394..2739684) 1 NC_014550.1 phenylacetate-CoA oxygenase is comprised of a five gene complex responsible for the hydroxylation of phenylacetate-CoA as the second catabolic step in phenylacetic acid degradation. Although the exact function of this enzyme has not been determined, it has been shown to be required for phenylacetic acid degradation and has been proposed to function in a multicomponent oxygenase acting on phenylacetate-CoA; phenylacetate-CoA oxygenase subunit PaaH 2739684 paaH 9794168 paaH Arthrobacter arilaitensis Re117 phenylacetate-CoA oxygenase subunit PaaH YP_003917624.1 2739394 R 861360 CDS YP_003917625.1 308178219 9794167 complement(2739686..2740672) 1 NC_014550.1 phenylacetate-CoA oxygenase is comprised of a five gene complex responsible for the hydroxylation of phenylacetate-CoA as the second catabolic step in phenylacetic acid degradation. Although the exact function of this enzyme has not been determined, it has been shown to be required for phenylacetic acid degradation and has been proposed to function in a multicomponent oxygenase acting on phenylacetate-CoA; phenylacetate-CoA oxygenase subunit PaaG 2740672 paaG 9794167 paaG Arthrobacter arilaitensis Re117 phenylacetate-CoA oxygenase subunit PaaG YP_003917625.1 2739686 R 861360 CDS YP_003917626.1 308178220 9794166 complement(2740816..2741265) 1 NC_014550.1 4 transmembrane helices predicted by TMHMM2.0; hypothetical protein 2741265 9794166 AARI_24350 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917626.1 2740816 R 861360 CDS YP_003917627.1 308178221 9794955 complement(2741466..2742221) 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, polar amino acid uptake transporter (PAAT) family (TC 3.A.1.3.z). ABCISSE: ABC transporter, ATP-binding protein (ABC), PAO-family (polar amino acid and opines). The PAO family includes transport systems for amino acids that have polar or charged side chains: lysine, histidine, ornithine, arginine, glutamine, glutamate, cystine and diaminopimelic acid; polar amino acid ABC transporter ATP-binding subunit 2742221 9794955 AARI_24360 Arthrobacter arilaitensis Re117 polar amino acid ABC transporter ATP-binding subunit YP_003917627.1 2741466 R 861360 CDS YP_003917628.1 308178222 9794956 complement(2742218..2743687) 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, polar amino acid uptake transporter (PAAT) family (TC 3.A.1.3.z). ABCISSE: ABC transporter, permease and binding protein (BP-IM), PAO-family (polar amino acid and opines). The PAO family includes transport systems for amino acids that have polar or charged side chains: lysine, histidine, ornithine, arginine, glutamine, glutamate, cystine and diaminopimelic acid; polar amino acid ABC transporter inner membrane and binding protein subunit 2743687 9794956 AARI_24370 Arthrobacter arilaitensis Re117 polar amino acid ABC transporter inner membrane and binding protein subunit YP_003917628.1 2742218 R 861360 CDS YP_003917629.1 308178223 9794957 2743891..2746044 1 NC_014550.1 oligopeptidase B cleaves peptide bonds on the C- terminal side of lysyl and argininyl residues. Prolyl oligopeptidase family protein (match to PF00326 and PF02897); oligopeptidase B 2746044 ptrB 9794957 ptrB Arthrobacter arilaitensis Re117 oligopeptidase B YP_003917629.1 2743891 D 861360 CDS YP_003917630.1 308178224 9794241 2746066..2747079 1 NC_014550.1 match to PF00583: acetyltransferase (GNAT) family. Match to PF042229: Uncharacterised protein family (UPF0157); GNAT family acetyltransferase 2747079 9794241 AARI_24390 Arthrobacter arilaitensis Re117 GNAT family acetyltransferase YP_003917630.1 2746066 D 861360 CDS YP_003917631.1 308178225 9794958 2747174..2747620 1 NC_014550.1 PaaD protein is nearly always found adjacent to other genes of the phenylacetic acid degradation pathway. Its function is currently unknown, but a role as thioesterases is suggested; phenylacetic acid degradation protein PaaD 2747620 paaD 9794958 paaD Arthrobacter arilaitensis Re117 phenylacetic acid degradation protein PaaD YP_003917631.1 2747174 D 861360 CDS YP_003917632.1 308178226 9794164 2747653..2748972 1 NC_014550.1 catalyses the formation of phenylacetyl-CoA from phenylacetate. Involved in the catabolism of phenylacetic acid; phenylacetate--CoA ligase 2748972 paaF 9794164 paaF Arthrobacter arilaitensis Re117 phenylacetate--CoA ligase YP_003917632.1 2747653 D 861360 CDS YP_003917633.1 308178227 9794165 2749004..2749621 1 NC_014550.1 identified by match to PF00440: bacterial regulatory proteins, tetR family; TetR family transcriptional regulator 2749621 9794165 AARI_24420 Arthrobacter arilaitensis Re117 TetR family transcriptional regulator YP_003917633.1 2749004 D 861360 CDS YP_003917634.1 308178228 9794959 2749773..2750552 1 NC_014550.1 7 transmembrane helices predicted by TMHMM2.0; hypothetical protein 2750552 9794959 AARI_24430 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917634.1 2749773 D 861360 CDS YP_003917635.1 308178229 9794960 complement(2750610..2752319) 1 NC_014550.1 enzymes of this family comprise mostly alpha- amylases (EC 3.2.1.1); pullulanases (EC 3.2.1.41); cyclomaltodextrin glucanotransferase (EC 2.4.1.19); cyclomaltodextrinase (EC 3.2.1.54); trehalose-6-phosphate hydrolase (EC 3.2.1.93); malto-oligosyltrehalose trehalohydrolase (EC 3.2.1.141); glycosyl hydrolase family 13 protein 2752319 9794960 AARI_24440 Arthrobacter arilaitensis Re117 glycosyl hydrolase family 13 protein YP_003917635.1 2750610 R 861360 CDS YP_003917636.1 308178230 9794961 complement(2752713..2754836) 1 NC_014550.1 involved in aromatic ring opening step of the phenylacetic acid catabolic pathway; phenylacetic acid degradation protein PaaN 2754836 paaN 9794961 paaN Arthrobacter arilaitensis Re117 phenylacetic acid degradation protein PaaN YP_003917636.1 2752713 R 861360 CDS YP_003917637.1 308178231 9794171 complement(2754952..2755674) 1 NC_014550.1 match to PS00383 pattern (tyrosine specific protein phosphatases active site) and PS50056 (tyrosine specific protein phosphatases family profile); hypothetical protein 2755674 9794171 AARI_24460 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917637.1 2754952 R 861360 CDS YP_003917638.1 308178232 9794962 2755815..2756717 1 NC_014550.1 identified by match to protein family PF01163. Protein kinases are a group of enzymes that possess a catalytic subunit which transfers the gamma phosphate from nucleotide triphosphates (often ATP) to one or more amino acid residues in a protein substrate side chain, resulting in a conformational change affecting protein function. They play a role in a mulititude of cellular processes, including division, proliferation, apoptosis, and differentiation; RIO-type Ser/Thr protein kinase 2756717 9794962 AARI_24470 Arthrobacter arilaitensis Re117 RIO-type Ser/Thr protein kinase YP_003917638.1 2755815 D 861360 CDS YP_003917639.1 308178233 9794963 complement(2756798..2757670) 1 NC_014550.1 3-hydroxyacyl-CoA dehydrogenase is an enzyme involved in fatty acid metabolism. It catalyzes the reduction of 3-hydroxyacyl-CoA to 3-oxoacyl-CoA; 3-hydroxyacyl-CoA dehydrogenase 2757670 9794963 AARI_24480 Arthrobacter arilaitensis Re117 3-hydroxyacyl-CoA dehydrogenase YP_003917639.1 2756798 R 861360 CDS YP_003917640.1 308178234 9794964 complement(2757673..2758467) 1 NC_014550.1 enoyl-CoA hydratase is involved in fatty acid metabolism. It catalyzes the hydratation of 2-trans-enoyl- CoA into 3-hydroxyacyl-CoA; enoyl-CoA hydratase 2758467 9794964 AARI_24490 Arthrobacter arilaitensis Re117 enoyl-CoA hydratase YP_003917640.1 2757673 R 861360 CDS YP_003917641.1 308178235 9794965 complement(2758469..2759692) 1 NC_014550.1 acetyl-CoA C-acyltransferase (also named 3-ketoacyl- CoA thiolase or thiolase I) has a broad chain-length specificity for its substrates and is involved in degradative pathways such as fatty acid beta-oxidation; acetyl-CoA C-acyltransferase 2759692 9794965 AARI_24500 Arthrobacter arilaitensis Re117 acetyl-CoA C-acyltransferase YP_003917641.1 2758469 R 861360 CDS YP_003917642.1 308178236 9794966 2760029..2761456 1 NC_014550.1 identified by similarity to protein SP:P0C0L7 (Escherichia coli). Proton symporter that senses osmotic shifts and responds by importing osmolytes such as proline, glycine betaine, stachydrine, pipecolic acid, ectoine and taurine. It is both an osmosensor and an osmoregulator which is available to participate early in the bacterial osmoregulatory response. Metabolite:H+ symporter (MHS) family, (Poline/glycine-betaine):(H+/Na+) symporter (also transports taurine, ectoine, pipecolate, proline-betaine, N,N-dimethylglycine, carnitine, and 1- carboxymethyl-pyridinium) (subject to osmotic activation) (TC 2.A.1.6.4); proline/betaine transporter 2761456 proP 9794966 proP Arthrobacter arilaitensis Re117 proline/betaine transporter YP_003917642.1 2760029 D 861360 CDS YP_003917643.1 308178237 9794227 complement(2761539..2762978) 1 NC_014550.1 amino acid-polyamine-organocation (APC) superfamily, amino acid transporter (AAT) family, asparagine permease (AnsP) (TC 2.A.3.1.8); L-asparagine permease 2762978 ansP 9794227 ansP Arthrobacter arilaitensis Re117 L-asparagine permease YP_003917643.1 2761539 R 861360 CDS YP_003917644.1 308178238 9793667 2763164..2764126 1 NC_014550.1 converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoic acid (DHNA): o-succinylbenzoyl-CoA <=> CoA + 1,4-dihydroxy-2-naphthoate; naphthoate synthase 2764126 menB 9793667 menB Arthrobacter arilaitensis Re117 naphthoate synthase YP_003917644.1 2763164 D 861360 CDS YP_003917645.1 308178239 9794062 2764155..2765282 1 NC_014550.1 converts 2-succinylbenzoate (OSB) to 2- succinylbenzoyl-CoA (OSB-CoA) : ATP + 2-succinylbenzoate + CoA = AMP + diphosphate + 2-succinylbenzoyl-CoA; O-succinylbenzoate-CoA ligase 2765282 menE 9794062 menE Arthrobacter arilaitensis Re117 O-succinylbenzoate-CoA ligase YP_003917645.1 2764155 D 861360 CDS YP_003917646.1 308178240 9794065 2765359..2766243 1 NC_014550.1 converts 1,4-dihydroxy-2-naphthoate (DHNA) to dimethylmenaquinone (DMK); 1,4-dihydroxy-2-naphthoate octaprenyltransferase 2766243 menA 9794065 menA Arthrobacter arilaitensis Re117 1,4-dihydroxy-2-naphthoate octaprenyltransferase YP_003917646.1 2765359 D 861360 CDS YP_003917647.1 308178241 9794061 complement(2766379..2766669) 1 NC_014550.1 2 transmembrane helices predicted by TMHMM2.0; hypothetical protein 2766669 9794061 AARI_24560 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917647.1 2766379 R 861360 CDS YP_003917648.1 308178242 9794967 2766723..2767172 1 NC_014550.1 signal peptide predicted by SignalP 3.0 HMM (probability: 0.947) with cleavage site probability 0.685 between position 26 and 27; hypothetical protein 2767172 9794967 AARI_24570 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917648.1 2766723 D 861360 CDS YP_003917649.1 308178243 9794968 complement(2767368..2768435) 1 NC_014550.1 identified by match to protein family PF01578; cytochrome C assembly protein 2768435 9794968 AARI_24580 Arthrobacter arilaitensis Re117 cytochrome C assembly protein YP_003917649.1 2767368 R 861360 CDS YP_003917650.1 308178244 9794969 complement(2768428..2770056) 1 NC_014550.1 identified by match to protein family PF05140; cytochrome C biosynthesis protein 2770056 9794969 AARI_24590 Arthrobacter arilaitensis Re117 cytochrome C biosynthesis protein YP_003917650.1 2768428 R 861360 CDS YP_003917651.1 308178245 9794970 complement(2770056..2770811) 1 NC_014550.1 identified by match to PF02683: Cytochrome C biogenesis protein transmembrane region; cytochrome C biosynthesis protein 2770811 9794970 AARI_24600 Arthrobacter arilaitensis Re117 cytochrome C biosynthesis protein YP_003917651.1 2770056 R 861360 CDS YP_003917652.1 308178246 9794971 complement(2770820..2771443) 1 NC_014550.1 identified by match to protein family PF08534. This family of redoxins includes peroxiredoxin, thioredoxin and glutaredoxin proteins; redoxin domain-containing protein 2771443 9794971 AARI_24610 Arthrobacter arilaitensis Re117 redoxin domain-containing protein YP_003917652.1 2770820 R 861360 CDS YP_003917653.1 308178247 9794972 complement(2771450..2772112) 1 NC_014550.1 identified by match to protein domain PF00300; phosphoglycerate mutase family protein 2772112 9794972 AARI_24620 Arthrobacter arilaitensis Re117 phosphoglycerate mutase family protein YP_003917653.1 2771450 R 861360 CDS YP_003917654.1 308178248 9794973 2772286..2773041 1 NC_014550.1 4 transmembrane helices predicted by TMHMM2.0; hypothetical protein 2773041 9794973 AARI_24630 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917654.1 2772286 D 861360 CDS YP_003917655.1 308178249 9794974 complement(2773158..2773793) 1 NC_014550.1 modulates transcription in response to the NADH/NAD(+) redox state; redox-sensing transcriptional repressor Rex 2773793 rex 9794974 rex Arthrobacter arilaitensis Re117 redox-sensing transcriptional repressor Rex YP_003917655.1 2773158 R 861360 CDS YP_003917656.1 308178250 9794293 complement(2773860..2774096) 1 NC_014550.1 identified by match to PF05768: glutaredoxin-like domain (DUF836). This family contains several viral glutaredoxins, and many related bacterial and eukaryotic proteins of unknown function. Glutaredoxins are small proteins of approximately one hundred amino-acid residues which utilise glutathione and NADPH as cofactors. Oxidized glutathione is regenerated by glutathione reductase; glutaredoxin 2774096 9794293 AARI_24650 Arthrobacter arilaitensis Re117 glutaredoxin YP_003917656.1 2773860 R 861360 CDS YP_003917657.1 308178251 9794975 2774168..2774974 1 NC_014550.1 identified by match to PF00702. This family includes L-2-haloacid dehalogenase, epoxide hydrolases and phosphatases; haloacid dehalogenase 2774974 9794975 AARI_24660 Arthrobacter arilaitensis Re117 haloacid dehalogenase YP_003917657.1 2774168 D 861360 CDS YP_003917658.1 308178252 9794976 complement(2775315..2775539) 1 NC_014550.1 hypothetical protein 2775539 9794976 AARI_24670 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917658.1 2775315 R 861360 CDS YP_003917659.1 308178253 9794977 complement(2775799..2777142) 1 NC_014550.1 catalyses the conversion of 2-oxoglutarate to glutamate; NADP-specific glutamate dehydrogenase 2777142 gdhA 9794977 gdhA Arthrobacter arilaitensis Re117 NADP-specific glutamate dehydrogenase YP_003917659.1 2775799 R 861360 CDS YP_003917660.1 308178254 9793896 complement(2777333..2777770) 1 NC_014550.1 identified by match to PF01022: bacterial regulatory protein, ArsR family. ArsR-family transcriptional regulators include several proteins that appear to dissociate from DNA in the presence of metal ions; ArsR family transcriptional regulator 2777770 9793896 AARI_24690 Arthrobacter arilaitensis Re117 ArsR family transcriptional regulator YP_003917660.1 2777333 R 861360 CDS YP_003917661.1 308178255 9794978 complement(2777872..2779074) 1 NC_014550.1 AcuC may be involved in growth of some bacteria on butanediol and acetoin; acetoin utilization protein AcuC 2779074 acuC 9794978 acuC Arthrobacter arilaitensis Re117 acetoin utilization protein AcuC YP_003917661.1 2777872 R 861360 CDS YP_003917662.1 308178256 9793656 2779248..2780681 1 NC_014550.1 K+ transporter (Trk) family (TC 2.A.38.y.z). Membrane component of a Trk-type K+ transport system. Match to protein family PF02386; Trk system potassium uptake protein TrkH 2780681 trkH 9793656 trkH Arthrobacter arilaitensis Re117 Trk system potassium uptake protein TrkH YP_003917662.1 2779248 D 861360 CDS YP_003917663.1 308178257 9794463 2780674..2781345 1 NC_014550.1 voltage-gated K+ Channel beta-subunit family, TrkA regulatory subunit of TrkH and TrkG (TC 8.A.5.2.1). Part of a potassium transport system (regulatory subunit). TrkA domains can bind NAD+ and NADH, possibly allowing K+ transporters to be responsive to the redox state of the cell. Systems regulated by TrkA include TrkG/H (TC 2.A.38. 1.1); Trk system potassium uptake protein TrkA 2781345 trkA 9794463 trkA Arthrobacter arilaitensis Re117 Trk system potassium uptake protein TrkA YP_003917663.1 2780674 D 861360 CDS YP_003917664.1 308178258 9794462 complement(2781422..2782264) 1 NC_014550.1 catalyses the terminal step in the biosynthesis of proline from glutamate, the NAD(P) dependent oxidation of 1-pyrroline-5-carboxylate into proline; pyrroline-5-carboxylate reductase 2782264 proC 9794462 proC Arthrobacter arilaitensis Re117 pyrroline-5-carboxylate reductase YP_003917664.1 2781422 R 861360 CDS YP_003917665.1 308178259 9794225 complement(2782269..2783093) 1 NC_014550.1 match to protein domain PF01261: xylose isomerase- like TIM barrel . This TIM alpha/beta barrel structure is found in xylose isomerase and in endonuclease IV (EC.1.21. 2). This domain is also found in the N termini of bacterial myo-inositol catabolism proteins; xylose isomerase-like protein 2783093 9794225 AARI_24740 Arthrobacter arilaitensis Re117 xylose isomerase-like protein YP_003917665.1 2782269 R 861360 CDS YP_003917666.1 308178260 9794979 complement(2783148..2784167) 1 NC_014550.1 identified by match to protein family PF02541. Similar to exopolyphosphatase (Ppx, EC 3.6.1.11) and guanosine pentaphosphate phospho-hydrolase (GppA, EC 3.6.1. 40) proteins; Ppx/GppA phosphatase family protein 2784167 9794979 AARI_24750 Arthrobacter arilaitensis Re117 Ppx/GppA phosphatase family protein YP_003917666.1 2783148 R 861360 CDS YP_003917667.1 308178261 9794980 complement(2784200..2786989) 1 NC_014550.1 catalytic activity: ATP-independent breakage of single-stranded DNA, followed by passage and rejoining; DNA topoisomerase I 2786989 topA 9794980 topA Arthrobacter arilaitensis Re117 DNA topoisomerase I YP_003917667.1 2784200 R 861360 CDS YP_003917668.1 308178262 9794457 complement(2787139..2787789) 1 NC_014550.1 identified by match to PF01022. ArsR-family transcriptional regulators include several proteins that appear to dissociate from DNA in the presence of metal ions; ArsR family transcriptional regulator 2787789 9794457 AARI_24770 Arthrobacter arilaitensis Re117 ArsR family transcriptional regulator YP_003917668.1 2787139 R 861360 CDS YP_003917669.1 308178263 9794981 complement(2787813..2789402) 1 NC_014550.1 match to protein domain PF05175. This domain is found in ribosomal RNA small subunit methyltransferase C as well as other methyltransferases; methyltransferase 2789402 9794981 AARI_24780 Arthrobacter arilaitensis Re117 methyltransferase YP_003917669.1 2787813 R 861360 CDS YP_003917670.1 308178264 9794982 2789475..2790053 1 NC_014550.1 identified by match to PF00583: acetyltransferase (GNAT) family; GNAT family acetyltransferase 2790053 9794982 AARI_24790 Arthrobacter arilaitensis Re117 GNAT family acetyltransferase YP_003917670.1 2789475 D 861360 CDS YP_003917671.1 308178265 9794983 complement(2790107..2791006) 1 NC_014550.1 predicted sulfurtransferase; hypothetical protein 2791006 9794983 AARI_24800 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917671.1 2790107 R 861360 CDS YP_003917672.1 308178266 9794984 2791172..2791828 1 NC_014550.1 identified by match to PF00583: acetyltransferase (GNAT) family; GNAT family acetyltransferase 2791828 9794984 AARI_24810 Arthrobacter arilaitensis Re117 GNAT family acetyltransferase YP_003917672.1 2791172 D 861360 CDS YP_003917673.1 308178267 9794985 2791930..2794260 1 NC_014550.1 possible DNA or RNA helicase; ATP-dependent helicase 2794260 9794985 AARI_24820 Arthrobacter arilaitensis Re117 ATP-dependent helicase YP_003917673.1 2791930 D 861360 CDS YP_003917674.1 308178268 9794986 complement(2794276..2794671) 1 NC_014550.1 signal peptide predicted by SignalP 3.0 HMM (probability: 1.000) with cleavage site probability 0.710 between position 48 and 49; hypothetical protein 2794671 9794986 AARI_24830 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917674.1 2794276 R 861360 CDS YP_003917675.1 308178269 9794987 complement(2794668..2795003) 1 NC_014550.1 1 transmembrane helice predicted by TMHMM2.0; hypothetical protein 2795003 9794987 AARI_24840 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917675.1 2794668 R 861360 CDS YP_003917676.1 308178270 9794988 complement(2795007..2795189) 1 NC_014550.1 hypothetical protein 2795189 9794988 AARI_24850 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917676.1 2795007 R 861360 CDS YP_003917677.1 308178271 9794992 2798463..2798573 1 NC_014550.1 hypothetical protein 2798573 9794992 AARI_24890 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917677.1 2798463 D 861360 CDS YP_003917678.1 308178272 9794993 complement(2798649..2798924) 1 NC_014550.1 3 transmembrane helices predicted by TMHMM2.0; hypothetical protein 2798924 9794993 AARI_24900 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917678.1 2798649 R 861360 CDS YP_003917679.1 308178273 9794994 complement(2798958..2799518) 1 NC_014550.1 signal peptide predicted by SignalP 3.0 HMM (probability: 1.000) with cleavage site probability 0.984 between position 32 and 33; hypothetical protein 2799518 9794994 AARI_24910 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917679.1 2798958 R 861360 CDS YP_003917680.1 308178274 9794995 2799856..2800365 1 NC_014550.1 hypothetical protein 2800365 9794995 AARI_24920 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917680.1 2799856 D 861360 CDS YP_003917681.1 308178275 9794996 complement(2800383..2800616) 1 NC_014550.1 hypothetical protein 2800616 9794996 AARI_24930 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917681.1 2800383 R 861360 CDS YP_003917682.1 308178276 9794997 complement(2800742..2801278) 1 NC_014550.1 signal peptide predicted by SignalP 3.0 HMM (probability: 0.691) with cleavage site probability 0.462 between position 29 and 30. 1 transmembrane helice predicted by TMHMM2.0 after the signal peptide; hypothetical protein 2801278 9794997 AARI_24940 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917682.1 2800742 R 861360 CDS YP_003917683.1 308178277 9794998 complement(2801275..2801949) 1 NC_014550.1 signal peptide predicted by SignalP 3.0 HMM (probability: 0.998) with cleavage site probability 0.533 between position 21 and 22. 2 transmembrane helices predicted by TMHMM2.0 after the signal peptide; hypothetical protein 2801949 9794998 AARI_24950 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917683.1 2801275 R 861360 CDS YP_003917684.1 308178278 9794999 complement(2801953..2803194) 1 NC_014550.1 identified by match to protein domain PF00437; type II/IV secretion system protein E 2803194 9794999 AARI_24960 Arthrobacter arilaitensis Re117 type II/IV secretion system protein E YP_003917684.1 2801953 R 861360 CDS YP_003917685.1 308178279 9795000 complement(2803194..2804258) 1 NC_014550.1 hypothetical protein 2804258 9795000 AARI_24970 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917685.1 2803194 R 861360 CDS YP_003917686.1 308178280 9795001 2804403..2806052 1 NC_014550.1 DNA polymerase I 2806052 9795001 AARI_24980 Arthrobacter arilaitensis Re117 DNA polymerase I YP_003917686.1 2804403 D 861360 CDS YP_003917687.1 308178281 9795002 complement(2806059..2806736) 1 NC_014550.1 identified by match to PF00293. Members of the Nudix hydrolase superfamily catalyze the hydrolysis of nucleoside diphosphates linked to other moieties. Substrates of nudix hydrolases include intact and oxidatively damaged nucleoside triphosphates, dinucleoside polyphosphates, nucleotide-sugars and dinucleotide enzymes. These substrates are metabolites or cell signaling molecules that require regulation during different stages of the cell cycle or during periods of stress. In general, the role of the nudix hydrolase is to sanitize the nucleotide pools and to maintain cell viability, thereby serving as surveillance and house- cleaning enzymes; NUDIX hydrolase 2806736 9795002 AARI_24990 Arthrobacter arilaitensis Re117 NUDIX hydrolase YP_003917687.1 2806059 R 861360 CDS YP_003917688.1 308178282 9795003 complement(2806733..2807527) 1 NC_014550.1 also named endonuclease III. It is a DNA repair enzyme that acts both as a DNA N-glycosylase, removing oxidized pyrimidines from DNA, and as an apurinic/apyrimidinic endonuclease, introducing a single- strand nick at the site from which the damaged base was removed; DNA-(apurinic or apyrimidinic site) lyase 2807527 nth 9795003 nth Arthrobacter arilaitensis Re117 DNA-(apurinic or apyrimidinic site) lyase YP_003917688.1 2806733 R 861360 CDS YP_003917689.1 308178283 9794151 2807712..2809709 1 NC_014550.1 catalyzes the formation of acetyl-CoA from acetate and CoA; acetate--CoA ligase 2809709 acsA 9794151 acsA Arthrobacter arilaitensis Re117 acetate--CoA ligase YP_003917689.1 2807712 D 861360 CDS YP_003917690.1 308178284 9793655 2809842..2810294 1 NC_014550.1 third enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid. Chorismic acid is a important intermediate in the synthesis of aromatic compounds, such as aromatic amino acids (phenylalanine, tyrosine and tryptophan), p-aminobenzoic acid, folate and ubiquinone; 3-dehydroquinate dehydratase 2810294 aroQ 9793655 aroQ Arthrobacter arilaitensis Re117 3-dehydroquinate dehydratase YP_003917690.1 2809842 D 861360 CDS YP_003917691.1 308178285 9793689 complement(2810305..2811498) 1 NC_014550.1 match to PF00089. This group of serine proteases belong to the MEROPS peptidase family S1 (chymotrypsin family, clan PA(S)) and to peptidase family S6 (Hap serine peptidases). 4 transmembrane helices predicted by TMHMM2.0; membrane-associated serine protease 2811498 9793689 AARI_25030 Arthrobacter arilaitensis Re117 membrane-associated serine protease YP_003917691.1 2810305 R 861360 CDS YP_003917692.1 308178286 9795004 2811700..2812377 1 NC_014550.1 cd00038: effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO sensor. In all cases binding of the effector leads to conformational changes and the ability to activate transcription; Crp/Fnr family transcriptional regulator 2812377 9795004 AARI_25040 Arthrobacter arilaitensis Re117 Crp/Fnr family transcriptional regulator YP_003917692.1 2811700 D 861360 CDS YP_003917693.1 308178287 9795005 complement(2812457..2813371) 1 NC_014550.1 identified by match to PF00293. Members of the Nudix hydrolase superfamily catalyze the hydrolysis of nucleoside diphosphates linked to other moieties. Substrates of nudix hydrolases include intact and oxidatively damaged nucleoside triphosphates, dinucleoside polyphosphates, nucleotide-sugars and dinucleotide enzymes. These substrates are metabolites or cell signaling molecules that require regulation during different stages of the cell cycle or during periods of stress. In general, the role of the nudix hydrolase is to sanitize the nucleotide pools and to maintain cell viability, thereby serving as surveillance and house- cleaning enzymes; NUDIX hydrolase 2813371 9795005 AARI_25050 Arthrobacter arilaitensis Re117 NUDIX hydrolase YP_003917693.1 2812457 R 861360 CDS YP_003917694.1 308178288 9795006 complement(2813433..2813909) 1 NC_014550.1 identified by match to protein domain PF01042: endoribonuclease L-PSP; endoribonuclease active on single- stranded mRNA. Inhibits protein synthesis by cleavage of mRNA. Previously thought to inhibit protein synthesis initiation. This protein may also be involved in the regulation of purine biosynthesis; endoribonuclease 2813909 9795006 AARI_25060 Arthrobacter arilaitensis Re117 endoribonuclease YP_003917694.1 2813433 R 861360 CDS YP_003917695.1 308178289 9795007 complement(2813942..2814097) 1 NC_014550.1 hypothetical protein 2814097 9795007 AARI_25070 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917695.1 2813942 R 861360 CDS YP_003917696.1 308178290 9795008 2814135..2816417 1 NC_014550.1 match to PF00912 and PF00905. Transglycosylase and transpeptidase in the N- and C-terminus respectively. The transglycosylase domain catalyses the polymerisation of murein glycan chains. Possibly involved in peptidoglycan biosynthesis; penicillin-binding protein 2816417 9795008 AARI_25080 Arthrobacter arilaitensis Re117 penicillin-binding protein YP_003917696.1 2814135 D 861360 CDS YP_003917697.1 308178291 9795009 2816538..2817491 1 NC_014550.1 match to protein domain PF00149. The metallophosphoesterase motif is found in a large number of proteins invoved in phosphoryation. These include Ser/Thr phosphatases, DNA polymerase, exonucleases, and other phosphatases; metallophosphoesterase domain-containing protein 2817491 9795009 AARI_25090 Arthrobacter arilaitensis Re117 metallophosphoesterase domain-containing protein YP_003917697.1 2816538 D 861360 CDS YP_003917698.1 308178292 9795010 2817664..2819487 1 NC_014550.1 TC 3.A.1.y.z. ABCISSE: ABC transporter, permease and ATP-binding protein (IM-ABC), DPL-family, LLP- subfamily (LIP-like exporters). The function of LIP-like exporters is presently unknown; ABC transporter ATPase and permease components 2819487 9795010 AARI_25100 Arthrobacter arilaitensis Re117 ABC transporter ATPase and permease components YP_003917698.1 2817664 D 861360 CDS YP_003917699.1 308178293 9795011 2819484..2821292 1 NC_014550.1 TC 3.A.1.y.z. ABCISSE: ABC transporter, permease and ATP-binding protein (IM-ABC), DPL-family, LLP- subfamily (LIP-like exporters). The function of LIP-like exporters is presently unknown; ABC transporter ATPase and permease components 2821292 9795011 AARI_25110 Arthrobacter arilaitensis Re117 ABC transporter ATPase and permease components YP_003917699.1 2819484 D 861360 CDS YP_003917700.1 308178294 9795012 complement(2821376..2822281) 1 NC_014550.1 catalyzes the seventh step of the de novo biosynthesis of purine nucleotides, the conversion of carboximideaminoimidazole ribonucleotide (CAIR) into succinoaminoimidazolecarboximide ribonucleotide (SAICAR); phosphoribosylaminoimidazolesuccinocarboxamide synthase 2822281 purC 9795012 purC Arthrobacter arilaitensis Re117 phosphoribosylaminoimidazolesuccinocarboxamide synthase YP_003917700.1 2821376 R 861360 CDS YP_003917701.1 308178295 9794246 complement(2822297..2823583) 1 NC_014550.1 catalyzes the second step in the de novo biosynthesis of purine, the ATP-dependent addition of 5- phosphoribosylamine to glycine to form 5- phosphoribosylglycinamide; phosphoribosylamine--glycine ligase 2823583 purD 9794246 purD Arthrobacter arilaitensis Re117 phosphoribosylamine--glycine ligase YP_003917701.1 2822297 R 861360 CDS YP_003917702.1 308178296 9794247 2823885..2824265 1 NC_014550.1 hypothetical protein 2824265 9794247 AARI_25140 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917702.1 2823885 D 861360 CDS YP_003917703.1 308178297 9795013 2824270..2824596 1 NC_014550.1 2 transmembrane helices predicted by TMHMM2.0; hypothetical protein 2824596 9795013 AARI_25150 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917703.1 2824270 D 861360 CDS YP_003917704.1 308178298 9795014 2824702..2826225 1 NC_014550.1 catalyzes the first step in purine biosynthesis, the transfer of the ammonia group of glutamine to PRPP to form 5-phosphoribosylamine; amidophosphoribosyltransferase 2826225 purF 9795014 purF Arthrobacter arilaitensis Re117 amidophosphoribosyltransferase YP_003917704.1 2824702 D 861360 CDS YP_003917705.1 308178299 9794249 2826233..2827447 1 NC_014550.1 catalyzes the conversion of formylglycinamide ribonucleotide (FGAM) and ATP to AIR, ADP, and Pi, the fifth step in de novo purine biosynthesis; phosphoribosylformylglycinamidine cyclo-ligase 2827447 purM 9794249 purM Arthrobacter arilaitensis Re117 phosphoribosylformylglycinamidine cyclo-ligase YP_003917705.1 2826233 D 861360 CDS YP_003917706.1 308178300 9794253 complement(2827560..2828450) 1 NC_014550.1 identified by match to PF02146: Sir2 family. Sir2 proteins, also known as sirtuins, are found in all eukaryotes and many archaea and prokaryotes and have been shown to regulate gene silencing, DNA repair, metabolic enzymes, and life span. Function: modulate the activities of several enzymes which are inactive in their acetylated form. Catalytic activity: NAD+ + an acetylprotein = nicotinamide + O-acetyl-ADP-ribose + a protein; NAD-dependent deacetylase 2828450 npdA 9794253 npdA Arthrobacter arilaitensis Re117 NAD-dependent deacetylase YP_003917706.1 2827560 R 861360 CDS YP_003917707.1 308178301 9794143 complement(2828641..2828859) 1 NC_014550.1 hypothetical protein 2828859 9794143 AARI_25190 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917707.1 2828641 R 861360 CDS YP_003917708.1 308178302 9795015 2829083..2829736 1 NC_014550.1 1 transmembrane helice predicted by TMHMM2.0; hypothetical protein 2829736 9795015 AARI_25200 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917708.1 2829083 D 861360 CDS YP_003917709.1 308178303 9795016 complement(2829812..2832400) 1 NC_014550.1 part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with dnaK, dnaJ and grpE. Acts before dnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of clpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by dnaK; chaperone protein ClpB 2832400 clpB 9795016 clpB Arthrobacter arilaitensis Re117 chaperone protein ClpB YP_003917709.1 2829812 R 861360 CDS YP_003917710.1 308178304 9793737 2832572..2833078 1 NC_014550.1 hypothetical protein 2833078 9793737 AARI_25220 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917710.1 2832572 D 861360 CDS YP_003917711.1 308178305 9795017 2833098..2833565 1 NC_014550.1 identified by match to PF00583: acetyltransferase (GNAT) family; GNAT family acetyltransferase 2833565 9795017 AARI_25230 Arthrobacter arilaitensis Re117 GNAT family acetyltransferase YP_003917711.1 2833098 D 861360 CDS YP_003917712.1 308178306 9795018 2833835..2835019 1 NC_014550.1 identified by match to protein family PF03741. This family contains a number of integral membrane proteins that also contains the TerC protein. TerC has been implicated in resistance to tellurium. This protein may be involved in efflux of tellurium ions; TerC family membrane protein 2835019 9795018 AARI_25240 Arthrobacter arilaitensis Re117 TerC family membrane protein YP_003917712.1 2833835 D 861360 CDS YP_003917713.1 308178307 9795020 complement(2835696..2836181) 1 NC_014550.1 hypothetical protein 2836181 9795020 AARI_25260 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917713.1 2835696 R 861360 CDS YP_003917714.1 308178308 9795021 complement(2836268..2836678) 1 NC_014550.1 4 transmembrane helices predicted by TMHMM2.0; hypothetical protein 2836678 9795021 AARI_25270 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917714.1 2836268 R 861360 CDS YP_003917715.1 308178309 9795022 2836806..2837663 1 NC_014550.1 catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; tRNA (guanine-N(7)-)-methyltransferase 2837663 trmB 9795022 trmB Arthrobacter arilaitensis Re117 tRNA (guanine-N(7)-)-methyltransferase YP_003917715.1 2836806 D 861360 CDS YP_003917716.1 308178310 9794464 2837714..2838340 1 NC_014550.1 identified by match to PF00583: acetyltransferase (GNAT) family; GNAT family acetyltransferase 2838340 9794464 AARI_25290 Arthrobacter arilaitensis Re117 GNAT family acetyltransferase YP_003917716.1 2837714 D 861360 CDS YP_003917717.1 308178311 9795023 complement(2838337..2838765) 1 NC_014550.1 heat shock protein regulators (HspR) have been shown to regulate expression of specific regulons in response to high temperature or high osmolarity in Streptomyces and Helicobacter, respectively. These proteins share the N-terminal DNA binding domain with other transcription regulators of the MerR superfamily that promote transcription by reconfiguring the spacer between the -35 and -10 promoter elements; heat shock protein regulator HspR 2838765 hspR 9795023 hspR Arthrobacter arilaitensis Re117 heat shock protein regulator HspR YP_003917717.1 2838337 R 861360 CDS YP_003917718.1 308178312 9793986 complement(2838879..2839853) 1 NC_014550.1 match to protein domain PF00226. DnaJ domains (J- domains) are associated with hsp70 heat-shock system and it is thought that this domain mediates the interaction. DnaJ-domain is therefore part of a chaperone (protein folding) system; DnaJ domain chaperone protein 2839853 9793986 AARI_25310 Arthrobacter arilaitensis Re117 DnaJ domain chaperone protein YP_003917718.1 2838879 R 861360 CDS YP_003917719.1 308178313 9795024 complement(2839938..2840519) 1 NC_014550.1 identified by match to protein family PF01025. Molecular chaperones are a diverse family of proteins that function to protect proteins in the intracellular milieu from irreversible aggregation during synthesis and in times of cellular stress. The bacterial molecular chaperone DnaK (Hsp70) is an enzyme that couples cycles of ATP binding, hydrolysis, and ADP release by an N-terminal ATP-hydrolysing domain to cycles of sequestration and release of unfolded proteins by a C-terminal substrate binding domain. In prokaryotes the grpE protein is the co- chaperone for DnaK, and acts as a nucleotide exchange factor, stimulating the rate of ADP release 5000-fold. DnaK is itself a weak ATPase; ATP hydrolysis by DnaK is stimulated by its interaction with another co-chaperone, DnaJ. Thus the co-chaperones DnaJ and GrpE are capable of tightly regulating the nucleotide-bound and substrate- bound state of DnaK in ways that are necessary for the normal housekeeping functions and stress-related functions of the DnaK molecular chaperone cycle; GrpE protein 2840519 grpE 9795024 grpE Arthrobacter arilaitensis Re117 GrpE protein YP_003917719.1 2839938 R 861360 CDS YP_003917720.1 308178314 9793939 complement(2840534..2842387) 1 NC_014550.1 identified by match to protein family TIGR02350. Molecular chaperones are a diverse family of proteins that function to protect proteins in the intracellular milieu from irreversible aggregation during synthesis and in times of cellular stress. The bacterial molecular chaperone DnaK (Hsp70) is an enzyme that couples cycles of ATP binding, hydrolysis, and ADP release by an N-terminal ATP-hydrolysing domain to cycles of sequestration and release of unfolded proteins by a C-terminal substrate binding domain. In prokaryotes, the grpE protein is a co- chaperone for DnaK, and acts as a nucleotide exchange factor, stimulating the rate of ADP release 5000-fold. DnaK is itself a weak ATPase; ATP hydrolysis by DnaK is stimulated by its interaction with another co-chaperone, DnaJ. Thus the co-chaperones DnaJ and GrpE are capable of tightly regulating the nucleotide-bound and substrate- bound state of DnaK in ways that are necessary for the normal housekeeping functions and stress-related functions of the DnaK molecular chaperone cycle; chaperone protein DnaK 2842387 dnaK 9793939 dnaK Arthrobacter arilaitensis Re117 chaperone protein DnaK YP_003917720.1 2840534 R 861360 CDS YP_003917721.1 308178315 9793826 2842561..2842869 1 NC_014550.1 2 transmembrane helices predicted by TMHMM2.0; hypothetical protein 2842869 9793826 AARI_25340 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917721.1 2842561 D 861360 CDS YP_003917722.1 308178316 9795028 complement(2849137..2850684) 1 NC_014550.1 DEAD box helicase. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression; ATP-dependent RNA helicase 2850684 9795028 AARI_25380 Arthrobacter arilaitensis Re117 ATP-dependent RNA helicase YP_003917722.1 2849137 R 861360 CDS YP_003917723.1 308178317 9795029 complement(2850986..2853127) 1 NC_014550.1 Resistance-Nodulation-Cell Division (RND) superfamily (TC 2.A.6.y.z); drug exporter of the RND superfamily 2853127 9795029 AARI_25390 Arthrobacter arilaitensis Re117 drug exporter of the RND superfamily YP_003917723.1 2850986 R 861360 CDS YP_003917724.1 308178318 9795030 2853258..2853746 1 NC_014550.1 identified by match to protein family PF01047. Regulators with the marR-type HTH domain are present in bacteria and archaea and control a variety of biological functions, including resistance to multiple antibiotics, household disinfectants, organic solvents, oxidative stress agents and regulation of the virulence factor synthesis in pathogens of humans and plants. Many of the marR-like regulators respond to aromatic compounds; MarR family transcriptional regulator 2853746 9795030 AARI_25400 Arthrobacter arilaitensis Re117 MarR family transcriptional regulator YP_003917724.1 2853258 D 861360 CDS YP_003917725.1 308178319 9795031 2853767..2854390 1 NC_014550.1 resistance to homoSer/Thr (RhtB) family protein (TC 2.A.76.y.z). The family includes homoserine, threonine and leucine efflux proteins. The transport reaction presumably catalyzed by members of the RhtB family is: amino acid (in) + nH+ (out) <--> amino acid (out) + nH+ (in); RHBT family amino acid transporter 2854390 9795031 AARI_25410 Arthrobacter arilaitensis Re117 RHBT family amino acid transporter YP_003917725.1 2853767 D 861360 CDS YP_003917726.1 308178320 9795032 2854530..2855039 1 NC_014550.1 identified by match to protein family PF01451. Protein tyrosine (pTyr) phosphorylation is a common post- translational modification which can create novel recognition motifs for protein interactions and cellular localisation, affect protein stability, and regulate enzyme activity. Consequently, maintaining an appropriate level of protein tyrosine phosphorylation is essential for many cellular functions. Tyrosine-specific protein phosphatases (PTPase; EC:3.1.3.48) catalyse the removal of a phosphate group attached to a tyrosine residue, using a cysteinyl-phosphate enzyme intermediate. These enzymes are key regulatory components in signal transduction pathways (such as the MAP kinase pathway) and cell cycle control, and are important in the control of cell growth, proliferation, differentiation and transformation. Low molecular weight (LMW) protein-tyrosine phosphatases (or acid phosphatase) act on tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates; low molecular weight protein-tyrosine-phosphatase 2855039 9795032 AARI_25420 Arthrobacter arilaitensis Re117 low molecular weight protein-tyrosine-phosphatase YP_003917726.1 2854530 D 861360 CDS YP_003917727.1 308178321 9795033 2855026..2857035 1 NC_014550.1 aminodeoxychorismate synthase catalyzes the biosynthesis of 4-amino-4-deoxychorismate from chorismate and glutamine. It is involved in folate biosynthesis; aminodeoxychorismate synthase 2857035 9795033 AARI_25430 Arthrobacter arilaitensis Re117 aminodeoxychorismate synthase YP_003917727.1 2855026 D 861360 CDS YP_003917728.1 308178322 9795034 complement(2857039..2858511) 1 NC_014550.1 cardiolipin synthase catalyzes the transfer of a phosphatidyl group to phosphodidylglycerol to form cardiolipin (diphosphatidylglycerol); cardiolipin synthase 2858511 cls 9795034 cls Arthrobacter arilaitensis Re117 cardiolipin synthase YP_003917728.1 2857039 R 861360 CDS YP_003917729.1 308178323 9793744 2858702..2859577 1 NC_014550.1 aminodeoxychorismate lyase converts 4- aminodeoxychorismate to pyruvate and p-aminobenzoate, a precursor of folic acid in bacteria; aminodeoxychorismate lyase 2859577 pabC 9793744 pabC Arthrobacter arilaitensis Re117 aminodeoxychorismate lyase YP_003917729.1 2858702 D 861360 CDS YP_003917730.1 308178324 9794172 complement(2859574..2861901) 1 NC_014550.1 TC 3.A.1.y.z. ABCISSE for N-terminal section of the protein: ABC transporter, fused ATP-binding protein (ABC2), CBY-family (Cobalt uptake, unknown), Y179- subfamily (CBU-like systems); C-terminal section of the protein: permease (IM), CBY-family, Y179-subfamily. The function of CBU-like systems is unknown; ABC transporter inner membrane and ATP-binding subunits 2861901 9794172 AARI_25460 Arthrobacter arilaitensis Re117 ABC transporter inner membrane and ATP-binding subunits YP_003917730.1 2859574 R 861360 CDS YP_003917731.1 308178325 9795035 complement(2861898..2862506) 1 NC_014550.1 6 transmembrane helices predicted by TMHMM2.0; hypothetical protein 2862506 9795035 AARI_25470 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917731.1 2861898 R 861360 CDS YP_003917732.1 308178326 9795036 2862776..2863018 1 NC_014550.1 2 transmembrane helices predicted by TMHMM2.0; hypothetical protein 2863018 9795036 AARI_25480 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917732.1 2862776 D 861360 CDS YP_003917733.1 308178327 9795037 complement(2863078..2863482) 1 NC_014550.1 identified by match to protein family PF03334. Na(+)/H(+) antiporters has several roles in bacterial cells: (i) establishment of an electrochemical potential of Na(+) across the cytoplasmic membrane, which is the driving force for Na(+)-coupled processes such as Na(+)/solute symport and Na(+)-driven flagellar rotation; (ii) extrusion of Na(+) and Li(+), which are toxic if accumulated at high concentrations in cells; (iii) intracellular pH regulation under alkaline conditions; and (iv) cell volume regulation; Na(+)/H(+) antiporter subunit G 2863482 mnhG 9795037 mnhG Arthrobacter arilaitensis Re117 Na(+)/H(+) antiporter subunit G YP_003917733.1 2863078 R 861360 CDS YP_003917734.1 308178328 9794089 complement(2863482..2863748) 1 NC_014550.1 Na(+)/H(+) antiporters has several roles in bacterial cells: (i) establishment of an electrochemical potential of Na(+) across the cytoplasmic membrane, which is the driving force for Na(+)-coupled processes such as Na(+)/solute symport and Na(+)-driven flagellar rotation; (ii) extrusion of Na(+) and Li(+), which are toxic if accumulated at high concentrations in cells; (iii) intracellular pH regulation under alkaline conditions; and (iv) cell volume regulation; Na(+)/H(+) antiporter subunit F 2863748 mnhF 9794089 mnhF Arthrobacter arilaitensis Re117 Na(+)/H(+) antiporter subunit F YP_003917734.1 2863482 R 861360 CDS YP_003917735.1 308178329 9794088 complement(2863751..2864380) 1 NC_014550.1 identified by match to protein family PF01899. Na(+)/H(+) antiporters has several roles in bacterial cells: (i) establishment of an electrochemical potential of Na(+) across the cytoplasmic membrane, which is the driving force for Na(+)-coupled processes such as Na(+)/solute symport and Na(+)-driven flagellar rotation; (ii) extrusion of Na(+) and Li(+), which are toxic if accumulated at high concentrations in cells; (iii) intracellular pH regulation under alkaline conditions; and (iv) cell volume regulation; Na(+)/H(+) antiporter subunit E 2864380 mnhE 9794088 mnhE Arthrobacter arilaitensis Re117 Na(+)/H(+) antiporter subunit E YP_003917735.1 2863751 R 861360 CDS YP_003917736.1 308178330 9794087 complement(2864389..2865990) 1 NC_014550.1 Na(+)/H(+) antiporters has several roles in bacterial cells: (i) establishment of an electrochemical potential of Na(+) across the cytoplasmic membrane, which is the driving force for Na(+)-coupled processes such as Na(+)/solute symport and Na(+)-driven flagellar rotation; (ii) extrusion of Na(+) and Li(+), which are toxic if accumulated at high concentrations in cells; (iii) intracellular pH regulation under alkaline conditions; and (iv) cell volume regulation; Na(+)/H(+) antiporter subunit D 2865990 mnhD 9794087 mnhD Arthrobacter arilaitensis Re117 Na(+)/H(+) antiporter subunit D YP_003917736.1 2864389 R 861360 CDS YP_003917737.1 308178331 9794086 complement(2865987..2866436) 1 NC_014550.1 Na(+)/H(+) antiporters has several roles in bacterial cells: (i) establishment of an electrochemical potential of Na(+) across the cytoplasmic membrane, which is the driving force for Na(+)-coupled processes such as Na(+)/solute symport and Na(+)-driven flagellar rotation; (ii) extrusion of Na(+) and Li(+), which are toxic if accumulated at high concentrations in cells; (iii) intracellular pH regulation under alkaline conditions; and (iv) cell volume regulation; Na(+)/H(+) antiporter subunit C 2866436 mnhC 9794086 mnhC Arthrobacter arilaitensis Re117 Na(+)/H(+) antiporter subunit C YP_003917737.1 2865987 R 861360 CDS YP_003917738.1 308178332 9794085 complement(2866433..2869402) 1 NC_014550.1 Na(+)/H(+) antiporters has several roles in bacterial cells: (i) establishment of an electrochemical potential of Na(+) across the cytoplasmic membrane, which is the driving force for Na(+)-coupled processes such as Na(+)/solute symport and Na(+)-driven flagellar rotation; (ii) extrusion of Na(+) and Li(+), which are toxic if accumulated at high concentrations in cells; (iii) intracellular pH regulation under alkaline conditions; and (iv) cell volume regulation; Na(+)/H(+) antiporter subunit A/B 2869402 9794085 AARI_25540 Arthrobacter arilaitensis Re117 Na(+)/H(+) antiporter subunit A/B YP_003917738.1 2866433 R 861360 CDS YP_003917739.1 308178333 9795038 2869630..2870949 1 NC_014550.1 major facilitator superfamily (TC 2.A.1.y.z). Identified by match to protein family PF07690 (Major Facilitator Superfamily); MFS superfamily transporter 2870949 9795038 AARI_25550 Arthrobacter arilaitensis Re117 MFS superfamily transporter YP_003917739.1 2869630 D 861360 CDS YP_003917740.1 308178334 9795039 complement(2871023..2871604) 1 NC_014550.1 catalyses the formation of dUMP from dCTP; dCTP deaminase 2871604 dcd 9795039 dcd Arthrobacter arilaitensis Re117 dCTP deaminase YP_003917740.1 2871023 R 861360 CDS YP_003917741.1 308178335 9793794 2871793..2872650 1 NC_014550.1 identified by match to protein family PF02557; D-alanyl-D-alanine carboxypeptidase 2872650 9793794 AARI_25570 Arthrobacter arilaitensis Re117 D-alanyl-D-alanine carboxypeptidase YP_003917741.1 2871793 D 861360 CDS YP_003917742.1 308178336 9795040 complement(2872657..2872998) 1 NC_014550.1 3 transmembrane helices predicted by TMHMM2.0; hypothetical protein 2872998 9795040 AARI_25580 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917742.1 2872657 R 861360 CDS YP_003917743.1 308178337 9795041 complement(2873160..2874866) 1 NC_014550.1 catalyzes the reversible hydration of fumarate to L- malate. Involved in the TCA cycle; fumarate hydratase class I 2874866 9795041 AARI_25590 Arthrobacter arilaitensis Re117 fumarate hydratase class I YP_003917743.1 2873160 R 861360 CDS YP_003917744.1 308178338 9795042 2874978..2875463 1 NC_014550.1 hypothetical protein 2875463 9795042 AARI_25600 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917744.1 2874978 D 861360 CDS YP_003917745.1 308178339 9793643 2875711..2876640 1 NC_014550.1 Auxin Efflux Carrier (AEC) Family (TC 2.A.69.y.z). Homologues of the AEC family are found in bacteria as well as in archaea. The K. pneumoniae homologues has been implicated in malonate uptake, the O. oeni homologue is a malate permease; RHBT family transporter 2876640 9793643 AARI_25610 Arthrobacter arilaitensis Re117 RHBT family transporter YP_003917745.1 2875711 D 861360 CDS YP_003917746.1 308178340 9795044 2876726..2877553 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, polar amino acid uptake transporter (PAAT) family, glutamate porter (TC 3.A.1.3.14). ABCISSE: ABC transporter, binding protein (BP), PAO-family (polar amino acid and opines), L- cystine impot. Part of the ABC transporter complex TcyABC involved in L-cystine import. Identified by similarity to protein SP:P94402 (Bacillus subtilis); L-cystine ABC transporter substrate-binding protein TcyA 2877553 tcyA 9795044 tcyA Arthrobacter arilaitensis Re117 L-cystine ABC transporter substrate-binding protein TcyA YP_003917746.1 2876726 D 861360 CDS YP_003917747.1 308178341 9794431 2877625..2878290 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, polar amino acid uptake transporter (PAAT) family, glutamate porter (TC 3.A.1.3.14). ABCISSE: ABC transporter, permease (IM), PAO-family (polar amino acid and opines), L-cystine impot. Part of the ABC transporter complex TcyABC involved in L-cystine import. Identified by similarity to protein SP:P42200 (Bacillus subtilis); L-cystine ABC transporter inner membrane subunit TcyB 2878290 tcyB 9794431 tcyB Arthrobacter arilaitensis Re117 L-cystine ABC transporter inner membrane subunit TcyB YP_003917747.1 2877625 D 861360 CDS YP_003917748.1 308178342 9794432 2878277..2879041 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, polar amino acid uptake transporter (PAAT) family, glutamate porter (TC 3.A.1.3.14). ABCISSE: ABC transporter, ATP- binding protein (ABC), PAO-family (polar amino acid and opines), L-cystine impot. Part of the ABC transporter complex TcyABC involved in L-cystine import. Identified by similarity to protein SP:P39456 (Bacillus subtilis); L-cystine ABC transporter ATP-binding subunit TcyC 2879041 tcyC 9794432 tcyC Arthrobacter arilaitensis Re117 L-cystine ABC transporter ATP-binding subunit TcyC YP_003917748.1 2878277 D 861360 CDS YP_003917749.1 308178343 9794433 2879060..2880589 1 NC_014550.1 hypothetical protein 2880589 9794433 AARI_25650 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917749.1 2879060 D 861360 CDS YP_003917750.1 308178344 9795045 2880705..2880938 1 NC_014550.1 2 transmembrane helices predicted by TMHMM2.0; hypothetical protein 2880938 9795045 AARI_25660 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917750.1 2880705 D 861360 CDS YP_003917751.1 308178345 9795046 2881121..2882143 1 NC_014550.1 hypothetical protein 2882143 9795046 AARI_25670 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917751.1 2881121 D 861360 CDS YP_003917752.1 308178346 9795047 complement(2882140..2883378) 1 NC_014550.1 major facilitator superfamily (TC 2.A.1.y.z). Identified by match to protein family PF07690 (Major Facilitator Superfamily); MFS superfamily transporter 2883378 9795047 AARI_25680 Arthrobacter arilaitensis Re117 MFS superfamily transporter YP_003917752.1 2882140 R 861360 CDS YP_003917753.1 308178347 9795048 complement(2883536..2885443) 1 NC_014550.1 match to PF01436: NHL repeat; NHL repeat-containing protein 2885443 9795048 AARI_25690 Arthrobacter arilaitensis Re117 NHL repeat-containing protein YP_003917753.1 2883536 R 861360 CDS YP_003917754.1 308178348 9795049 complement(2885591..2886352) 1 NC_014550.1 signal peptide predicted by SignalP 3.0 HMM (probability: 0.999) with cleavage site probability 0.474 between position 26 and 27; hypothetical protein 2886352 9795049 AARI_25700 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917754.1 2885591 R 861360 CDS YP_003917755.1 308178349 9795050 complement(2886345..2888399) 1 NC_014550.1 identified by match to protein family PF05425. Copper sequestering activity displayed by some bacteria is determined by copper-binding protein products of the copper resistance operon (cop). CopD, together with CopC, perform copper uptake into the cytoplasm; copper resistance protein D 2888399 9795050 AARI_25710 Arthrobacter arilaitensis Re117 copper resistance protein D YP_003917755.1 2886345 R 861360 CDS YP_003917756.1 308178350 9795051 complement(2888474..2889628) 1 NC_014550.1 identified by match to protein family PF04261. This family of dye-decolourising peroxidases lack a typical heme-binding region; Dyp-type peroxidase family protein 2889628 9795051 AARI_25720 Arthrobacter arilaitensis Re117 Dyp-type peroxidase family protein YP_003917756.1 2888474 R 861360 CDS YP_003917757.1 308178351 9795052 complement(2889615..2890133) 1 NC_014550.1 signal peptide predicted by SignalP 3.0 HMM (probability: 1.000) with cleavage site probability 0.391 between position 26 and 27; hypothetical protein 2890133 9795052 AARI_25730 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917757.1 2889615 R 861360 CDS YP_003917758.1 308178352 9795053 complement(2890211..2890771) 1 NC_014550.1 identified by match to protein family PF04234. CopC is a bacterial blue copper protein that binds 1 atom of copper per protein molecule. Along with CopA, CopC mediates copper resistance by sequestration of copper in the periplasm; copper resistance protein C 2890771 9795053 AARI_25740 Arthrobacter arilaitensis Re117 copper resistance protein C YP_003917758.1 2890211 R 861360 CDS YP_003917759.1 308178353 9795054 complement(2890815..2891462) 1 NC_014550.1 3 transmembrane helices predicted by TMHMM2.0; hypothetical protein 2891462 9795054 AARI_25750 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917759.1 2890815 R 861360 CDS YP_003917760.1 308178354 9795055 complement(2891576..2891860) 1 NC_014550.1 histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. Identified by match to protein family PF00216; DNA-binding protein HU 2891860 hup 9795055 hup Arthrobacter arilaitensis Re117 DNA-binding protein HU YP_003917760.1 2891576 R 861360 CDS YP_003917761.1 308178355 9793988 complement(2892134..2892418) 1 NC_014550.1 histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. Identified by match to protein family PF00216; DNA-binding protein HU 2892418 hup 9793988 hup Arthrobacter arilaitensis Re117 DNA-binding protein HU YP_003917761.1 2892134 R 861360 CDS YP_003917762.1 308178356 9793989 complement(2892594..2893562) 1 NC_014550.1 identified by match to PF00106. The short-chain dehydrogenases/reductases family (SDR) is a very large family of enzymes, most of which are known to be NAD- or NADP-dependent oxidoreductases; short-chain dehydrogenases/reductases family protein 2893562 9793989 AARI_25780 Arthrobacter arilaitensis Re117 short-chain dehydrogenases/reductases family protein YP_003917762.1 2892594 R 861360 CDS YP_003917763.1 308178357 9795056 2893667..2894248 1 NC_014550.1 hypothetical protein 2894248 9795056 AARI_25790 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917763.1 2893667 D 861360 CDS YP_003917764.1 308178358 9795057 complement(2894307..2894612) 1 NC_014550.1 part of the 30S ribosomal subunit. Contacts proteins S3 and S10; 30S ribosomal protein S14 2894612 rpsN 9795057 rpsN Arthrobacter arilaitensis Re117 30S ribosomal protein S14 YP_003917764.1 2894307 R 861360 CDS YP_003917765.1 308178359 9794361 complement(2894616..2894786) 1 NC_014550.1 part of the 50S ribosomal subunit. Cross-links to the P and E site tRNAs; 50S ribosomal protein L33 2894786 rpmG 9794361 rpmG Arthrobacter arilaitensis Re117 50S ribosomal protein L33 YP_003917765.1 2894616 R 861360 CDS YP_003917766.1 308178360 9794339 complement(2894789..2895025) 1 NC_014550.1 50S ribosomal protein L28 2895025 rpmB 9794339 rpmB Arthrobacter arilaitensis Re117 50S ribosomal protein L28 YP_003917766.1 2894789 R 861360 CDS YP_003917767.1 308178361 9794334 complement(2895354..2895854) 1 NC_014550.1 identified by match to protein family PF01047. Regulators with the marR-type HTH domain are present in bacteria and archaea and control a variety of biological functions, including resistance to multiple antibiotics, household disinfectants, organic solvents, oxidative stress agents and regulation of the virulence factor synthesis in pathogens of humans and plants. Many of the marR-like regulators respond to aromatic compounds; MarR family transcriptional regulator 2895854 9794334 AARI_25830 Arthrobacter arilaitensis Re117 MarR family transcriptional regulator YP_003917767.1 2895354 R 861360 CDS YP_003917768.1 308178362 9795058 complement(2896228..2897025) 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, Polyamine/Opine/Phosphonate Uptake Transporter (POPT) Family (TC 3.A.1.11.z). ABCISSE: ABC transporter, permease (IM), MOI-family, polyamine import. Part of an ABC transporter complex involved in import of polyamine (such as spermidine or putrescine); polyamine ABC transporter inner membrane subunit 2897025 9795058 AARI_25840 Arthrobacter arilaitensis Re117 polyamine ABC transporter inner membrane subunit YP_003917768.1 2896228 R 861360 CDS YP_003917769.1 308178363 9795059 complement(2897027..2897950) 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, Polyamine/Opine/Phosphonate Uptake Transporter (POPT) Family (TC 3.A.1.11.z). ABCISSE: ABC transporter, permease (IM), MOI-family, polyamine import. Part of an ABC transporter complex involved in import of polyamine (such as spermidine or putrescine); polyamine ABC transporter inner membrane subunit 2897950 9795059 AARI_25850 Arthrobacter arilaitensis Re117 polyamine ABC transporter inner membrane subunit YP_003917769.1 2897027 R 861360 CDS YP_003917770.1 308178364 9795060 complement(2897947..2899080) 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, Polyamine/Opine/Phosphonate Uptake Transporter (POPT) Family (TC 3.A.1.11.z). ABCISSE: ABC transporter, ATP- binding protein (ABC), MOI-family, polyamine import. Part of an ABC transporter complex involved in import of polyamine (such as spermidine or putrescine); polyamine ABC transporter ATP-binding subunit 2899080 9795060 AARI_25860 Arthrobacter arilaitensis Re117 polyamine ABC transporter ATP-binding subunit YP_003917770.1 2897947 R 861360 CDS YP_003917771.1 308178365 9795061 complement(2899077..2900300) 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, Polyamine/Opine/Phosphonate Uptake Transporter (POPT) Family (TC 3.A.1.11.z). ABCISSE: ABC transporter, binding protein (BP), MOI-family, polyamine import. Part of an ABC transporter complex involved in import of polyamine (such as spermidine or putrescine); polyamine ABC transporter substrate-binding protein 2900300 9795061 AARI_25870 Arthrobacter arilaitensis Re117 polyamine ABC transporter substrate-binding protein YP_003917771.1 2899077 R 861360 CDS YP_003917772.1 308178366 9795062 complement(2900316..2901545) 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, Polyamine/Opine/Phosphonate Uptake Transporter (POPT) Family (TC 3.A.1.11.z). ABCISSE: ABC transporter, binding protein (BP), MOI-family, polyamine import. Part of an ABC transporter complex involved in import of polyamine (such as spermidine or putrescine); polyamine ABC transporter substrate-binding protein 2901545 9795062 AARI_25880 Arthrobacter arilaitensis Re117 polyamine ABC transporter substrate-binding protein YP_003917772.1 2900316 R 861360 CDS YP_003917773.1 308178367 9795063 2901761..2902228 1 NC_014550.1 identified by match to protein family PF01037: AsnC_trans_reg, AsnC family; AsnC/Lrp family transcriptional regulator 2902228 9795063 AARI_25890 Arthrobacter arilaitensis Re117 AsnC/Lrp family transcriptional regulator YP_003917773.1 2901761 D 861360 CDS YP_003917774.1 308178368 9795064 2902225..2903604 1 NC_014550.1 identified by match to protein family PF00202: aminotransferase class-III; aminotransferase 2903604 9795064 AARI_25900 Arthrobacter arilaitensis Re117 aminotransferase YP_003917774.1 2902225 D 861360 CDS YP_003917775.1 308178369 9795065 2903762..2904820 1 NC_014550.1 match to PS00142 pattern: neutral zinc metallopeptidases, zinc-binding region signature; hypothetical protein 2904820 9795065 AARI_25910 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917775.1 2903762 D 861360 CDS YP_003917776.1 308178370 9795066 complement(2904850..2906502) 1 NC_014550.1 identified by match to cd00085: HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins; HNH endonuclease domain-containing protein 2906502 9795066 AARI_25920 Arthrobacter arilaitensis Re117 HNH endonuclease domain-containing protein YP_003917776.1 2904850 R 861360 CDS YP_003917777.1 308178371 9795067 complement(2906565..2908079) 1 NC_014550.1 match to protein family PF07905: purine catabolism regulatory protein-like family. The bacterial proteins found in this family are similar to the purine catabolism regulatory protein expressed by Bacillus subtilis (PucR, O32138). PucR is thought to be a transcriptional activator involved in the induction of the purine degradation pathway, and may contain a LysR-like DNA-binding domain. It is similar to LysR-type regulators in that it represses its own expression. The other members of this family are also annotated as being regulatory proteins; transcriptional regulator 2908079 9795067 AARI_25930 Arthrobacter arilaitensis Re117 transcriptional regulator YP_003917777.1 2906565 R 861360 CDS YP_003917778.1 308178372 9795068 2908200..2909702 1 NC_014550.1 methylmalonate-semialdehyde dehydrogenase catalyses the following reaction: 2-methyl-3-oxopropanoate + CoA + H(2)O + NAD(+) <=> propanoyl-CoA + HCO(3)(-) + NADH. Involved in the catabolism of valine; methylmalonate-semialdehyde dehydrogenase 2909702 msmA 9795068 msmA Arthrobacter arilaitensis Re117 methylmalonate-semialdehyde dehydrogenase YP_003917778.1 2908200 D 861360 CDS YP_003917779.1 308178373 9794110 2909707..2911074 1 NC_014550.1 identified by match to protein family PF00202: aminotransferase class-III; aminotransferase 2911074 9794110 AARI_25950 Arthrobacter arilaitensis Re117 aminotransferase YP_003917779.1 2909707 D 861360 CDS YP_003917780.1 308178374 9795069 2911132..2912490 1 NC_014550.1 identified by match to PF02913 and PF01565; FAD linked oxidase domain-containing protein 2912490 9795069 AARI_25960 Arthrobacter arilaitensis Re117 FAD linked oxidase domain-containing protein YP_003917780.1 2911132 D 861360 CDS YP_003917781.1 308178375 9795070 2912529..2912966 1 NC_014550.1 2 transmembrane helices predicted by TMHMM2.0; hypothetical protein 2912966 9795070 AARI_25970 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917781.1 2912529 D 861360 CDS YP_003917782.1 308178376 9795071 2913060..2913536 1 NC_014550.1 hypothetical protein 2913536 9795071 AARI_25980 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917782.1 2913060 D 861360 CDS YP_003917783.1 308178377 9795072 2913937..2914104 1 NC_014550.1 hypothetical protein 2914104 9795072 AARI_25990 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917783.1 2913937 D 861360 CDS YP_003917784.1 308178378 9795073 complement(2914128..2914967) 1 NC_014550.1 shikimate dehydrogenase is the fourth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid. Chorismic acid is a important intermediate in the synthesis of aromatic compounds, such as aromatic amino acids (phenylalanine, tyrosine and tryptophan), p- aminobenzoic acid, folate and ubiquinone; shikimate dehydrogenase-like protein 2914967 9795073 AARI_26000 Arthrobacter arilaitensis Re117 shikimate dehydrogenase-like protein YP_003917784.1 2914128 R 861360 CDS YP_003917785.1 308178379 9795074 2915046..2915456 1 NC_014550.1 similar to Mycobacterium smegmatis rifampin ADP- ribosyl transferase (AF001493). Inactivates rifampin by ribosylation; rifampin ADP-ribosyl transferase 2915456 arr 9795074 arr Arthrobacter arilaitensis Re117 rifampin ADP-ribosyl transferase YP_003917785.1 2915046 D 861360 CDS YP_003917786.1 308178380 9793690 complement(2915532..2916944) 1 NC_014550.1 aldehyde dehydrogenase family protein 2916944 9793690 AARI_26020 Arthrobacter arilaitensis Re117 aldehyde dehydrogenase family protein YP_003917786.1 2915532 R 861360 CDS YP_003917787.1 308178381 9795075 complement(2916970..2918400) 1 NC_014550.1 amino acid-polyamine-organocation (APC) Superfamily (TC 2.A.3.y.z); amino acid transporter 2918400 9795075 AARI_26030 Arthrobacter arilaitensis Re117 amino acid transporter YP_003917787.1 2916970 R 861360 CDS YP_003917788.1 308178382 9795076 complement(2918513..2919436) 1 NC_014550.1 identified by match to protein domain PF00165: bacterial regulatory helix-turn-helix proteins, AraC family; AraC family transcriptional regulator 2919436 9795076 AARI_26040 Arthrobacter arilaitensis Re117 AraC family transcriptional regulator YP_003917788.1 2918513 R 861360 CDS YP_003917789.1 308178383 9795077 complement(2919539..2920132) 1 NC_014550.1 match to PF00440: bacterial regulatory proteins, tetR family; transcriptional regulator 2920132 9795077 AARI_26050 Arthrobacter arilaitensis Re117 transcriptional regulator YP_003917789.1 2919539 R 861360 CDS YP_003917790.1 308178384 9795078 2920262..2922184 1 NC_014550.1 catalyses the oxidative deamination of primary amines (such as biogenic amines) to the corresponding aldehydes, with concomitant reduction of molecular oxygen to hydrogen peroxide. Identified by similarity to protein SP:P46881 (Arthrobacter globiformis); primary-amine oxidase 2922184 9795078 AARI_26060 Arthrobacter arilaitensis Re117 primary-amine oxidase YP_003917790.1 2920262 D 861360 CDS YP_003917791.1 308178385 9795079 2922159..2922608 1 NC_014550.1 4 transmembrane helices predicted by TMHMM2.0; hypothetical protein 2922608 9795079 AARI_26070 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917791.1 2922159 D 861360 CDS YP_003917792.1 308178386 9795080 2922885..2924330 1 NC_014550.1 FAD-dependent oxidoreductase 2924330 9795080 AARI_26080 Arthrobacter arilaitensis Re117 FAD-dependent oxidoreductase YP_003917792.1 2922885 D 861360 CDS YP_003917793.1 308178387 9795081 2924330..2924698 1 NC_014550.1 hypothetical protein 2924698 9795081 AARI_26090 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917793.1 2924330 D 861360 CDS YP_003917794.1 308178388 9795082 2924719..2926209 1 NC_014550.1 identified by match to protein family PF00171; aldehyde dehydrogenase family protein 2926209 9795082 AARI_26100 Arthrobacter arilaitensis Re117 aldehyde dehydrogenase family protein YP_003917794.1 2924719 D 861360 CDS YP_003917795.1 308178389 9795083 complement(2926196..2927338) 1 NC_014550.1 match to protein family PF04464. Possibly involved in teichoic acid biosynthesis; transferase 2927338 9795083 AARI_26110 Arthrobacter arilaitensis Re117 transferase YP_003917795.1 2926196 R 861360 CDS YP_003917796.1 308178390 9795084 complement(2927358..2928419) 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, Manganese/Zinc/Iron Chelate Uptake Transporter (MZT) Family (TC 3.A.1.15.z). ABCISSE: ABC transporter, binding protein (BP), MET-family. This family is comprised of systems involved in the uptake of various metallic cations such as iron, manganese and zinc; iron/manganese/zinc ABC transporter substrate-binding protein 2928419 9795084 AARI_26120 Arthrobacter arilaitensis Re117 iron/manganese/zinc ABC transporter substrate-binding protein YP_003917796.1 2927358 R 861360 CDS YP_003917797.1 308178391 9795085 complement(2928488..2929741) 1 NC_014550.1 identified by match to protein family PF07907. The sequences featured in this family are similar to two proteins expressed by Lactococcus lactis, YibE and YibF. Most of the members of this family are annotated as being membrane proteins, and in fact the sequences contain a high proportion of hydrophobic residues; YibE/F family protein 2929741 9795085 AARI_26130 Arthrobacter arilaitensis Re117 YibE/F family protein YP_003917797.1 2928488 R 861360 CDS YP_003917798.1 308178392 9795086 2929928..2931085 1 NC_014550.1 8 transmembrane helices predicted by TMHMM2.0; hypothetical protein 2931085 9795086 AARI_26140 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917798.1 2929928 D 861360 CDS YP_003917799.1 308178393 9795087 complement(2931141..2932196) 1 NC_014550.1 hypothetical protein 2932196 9795087 AARI_26150 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917799.1 2931141 R 861360 CDS YP_003917800.1 308178394 9795088 complement(2932412..2933521) 1 NC_014550.1 match to protein family PF00724: NADH:flavin oxidoreductase / NADH oxidase family; flavin oxidoreductase 2933521 9795088 AARI_26160 Arthrobacter arilaitensis Re117 flavin oxidoreductase YP_003917800.1 2932412 R 861360 CDS YP_003917801.1 308178395 9795089 complement(2933580..2934935) 1 NC_014550.1 TCDB: Mg2+ Transporter-E (MgtE) Family (TC 9.A.19.y. z). Proteins from this family are capable of transporting Mg2+ and Co2+ but not Ni2+; divalent cation transporter 2934935 9795089 AARI_26170 Arthrobacter arilaitensis Re117 divalent cation transporter YP_003917801.1 2933580 R 861360 CDS YP_003917802.1 308178396 9795090 complement(2935350..2936759) 1 NC_014550.1 catalyzes the dehydratation of L-serine into ammonia and pyruvate; L-serine ammonia-lyase 2936759 sdaA 9795090 sdaA Arthrobacter arilaitensis Re117 L-serine ammonia-lyase YP_003917802.1 2935350 R 861360 CDS YP_003917803.1 308178397 9794380 complement(2936948..2938270) 1 NC_014550.1 catalyzes the transfer of the hydroxymethyl group of serine to tetrahydrofolate to form 5,10- methylenetetrahydrofolate and glycine. Also catalyzes the reaction of glycine with acetaldehyde to form L-threonine; glycine hydroxymethyltransferase 2938270 glyA 9794380 glyA Arthrobacter arilaitensis Re117 glycine hydroxymethyltransferase YP_003917803.1 2936948 R 861360 CDS YP_003917804.1 308178398 9793926 complement(2938270..2938650) 1 NC_014550.1 glycine cleavage system H protein 2938650 gcvH 9793926 gcvH Arthrobacter arilaitensis Re117 glycine cleavage system H protein YP_003917804.1 2938270 R 861360 CDS YP_003917805.1 308178399 9793892 complement(2938712..2939839) 1 NC_014550.1 a component, with EC 1.4.4.2, EC 1.8.1.4 and the lipoyl-bearing H protein, of the glycine cleavage system, which catalyzes the oxidative cleavage of glycine to form NH3, C02, and 5,10-methylenetetrahydrofolate; aminomethyltransferase 2939839 gcvT 9793892 gcvT Arthrobacter arilaitensis Re117 aminomethyltransferase YP_003917805.1 2938712 R 861360 CDS YP_003917806.1 308178400 9793894 complement(2939853..2942699) 1 NC_014550.1 a component, with EC 2.1.2.10 and EC 1.8.1.4, of the glycine cleavage system; glycine dehydrogenase 2942699 gcvP 9793894 gcvP Arthrobacter arilaitensis Re117 glycine dehydrogenase YP_003917806.1 2939853 R 861360 CDS YP_003917807.1 308178401 9793893 complement(2943064..2943840) 1 NC_014550.1 identified by match to protein family PF00657; GDSL-like lipase/esterase 2943840 9793893 AARI_26230 Arthrobacter arilaitensis Re117 GDSL-like lipase/esterase YP_003917807.1 2943064 R 861360 CDS YP_003917808.1 308178402 9795091 complement(2943908..2945059) 1 NC_014550.1 identified by similarity to protein SP:Q44050 (Arthrobacter globiformis); carboxylesterase 2945059 9795091 AARI_26240 Arthrobacter arilaitensis Re117 carboxylesterase YP_003917808.1 2943908 R 861360 CDS YP_003917809.1 308178403 9795092 2945286..2946773 1 NC_014550.1 amino acid-polyamine-organocation (APC) Superfamily (TC 2.A.3.y.z); amino acid transporter 2946773 9795092 AARI_26250 Arthrobacter arilaitensis Re117 amino acid transporter YP_003917809.1 2945286 D 861360 CDS YP_003917810.1 308178404 9795093 complement(2946837..2947748) 1 NC_014550.1 ribonuclease H recognizes and cleaves the RNA strand of RNA-DNA heteroduplexes; ribonuclease H 2947748 9795093 AARI_26260 Arthrobacter arilaitensis Re117 ribonuclease H YP_003917810.1 2946837 R 861360 CDS YP_003917811.1 308178405 9795094 2947866..2948174 1 NC_014550.1 signal peptide predicted by SignalP 3.0 HMM (probability: 0.703) with cleavage site probability 0.284 between position 33 and 34; hypothetical protein 2948174 9795094 AARI_26270 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917811.1 2947866 D 861360 CDS YP_003917812.1 308178406 9795095 complement(2948243..2949352) 1 NC_014550.1 glutathione transferase is involved in cellular detoxification by catalyzing the conjugation of glutathione with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens, therapeutic drugs, environmental toxins, and products of oxidative stress; glutathione transferase 2949352 9795095 AARI_26280 Arthrobacter arilaitensis Re117 glutathione transferase YP_003917812.1 2948243 R 861360 CDS YP_003917813.1 308178407 9795096 complement(2949493..2949585) 1 NC_014550.1 hypothetical protein 2949585 9795096 AARI_26290 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917813.1 2949493 R 861360 CDS YP_003917814.1 308178408 9795097 2949749..2950234 1 NC_014550.1 identified by match to protein family PF01047. Regulators with the marR-type HTH domain are present in bacteria and archaea and control a variety of biological functions, including resistance to multiple antibiotics, household disinfectants, organic solvents, oxidative stress agents and regulation of the virulence factor synthesis in pathogens of humans and plants. Many of the marR-like regulators respond to aromatic compounds; MarR family transcriptional regulator 2950234 9795097 AARI_26300 Arthrobacter arilaitensis Re117 MarR family transcriptional regulator YP_003917814.1 2949749 D 861360 CDS YP_003917815.1 308178409 9795098 complement(2950231..2952060) 1 NC_014550.1 TC 3.A.1.y.z. ABCISSE: ABC transporter, permease and ATP-binding protein (IM-ABC), DPL-family, prokaryote drug export (PED) subfamily. Possible function in in antibiotic peptide or drug resistance or production (export); drug resistance ATP-binding protein 2952060 9795098 AARI_26310 Arthrobacter arilaitensis Re117 drug resistance ATP-binding protein YP_003917815.1 2950231 R 861360 CDS YP_003917816.1 308178410 9795099 2952166..2952642 1 NC_014550.1 identified by match to protein family PF01047. Regulators with the marR-type HTH domain are present in bacteria and archaea and control a variety of biological functions, including resistance to multiple antibiotics, household disinfectants, organic solvents, oxidative stress agents and regulation of the virulence factor synthesis in pathogens of humans and plants. Many of the marR-like regulators respond to aromatic compounds; MarR family transcriptional regulator 2952642 9795099 AARI_26320 Arthrobacter arilaitensis Re117 MarR family transcriptional regulator YP_003917816.1 2952166 D 861360 CDS YP_003917817.1 308178411 9795100 complement(2952667..2954574) 1 NC_014550.1 N-terminal part of the protein: iron-siderophore ABC transporter, ATP-binding subunit. TCDB: ATP-binding cassette (ABC) superfamily, iron chelate uptake transporter (FeCT) family (TC 3.A.1.14.z). ABCISSE: ABC transporter, ATP-binding protein (ABC), ISVH-family (iron siderophores, vitamin B12 and hemin). C-terminal part of the protein: siderophore-interacting protein. Possibly involved in removal of iron from iron-siderophore complexes; iron-siderophore uptake protein 2954574 9795100 AARI_26330 Arthrobacter arilaitensis Re117 iron-siderophore uptake protein YP_003917817.1 2952667 R 861360 CDS YP_003917818.1 308178412 9795101 complement(2954577..2955668) 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, iron chelate uptake transporter (FeCT) family (TC 3.A.1.14.z). ABCISSE: ABC transporter, permease (IM), ISVH-family (iron siderophores, vitamin B12 and hemin); iron-siderophore ABC transporter inner membrane subunit 2955668 9795101 AARI_26340 Arthrobacter arilaitensis Re117 iron-siderophore ABC transporter inner membrane subunit YP_003917818.1 2954577 R 861360 CDS YP_003917819.1 308178413 9795102 complement(2955680..2956729) 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, iron chelate uptake transporter (FeCT) family (TC 3.A.1.14.z). ABCISSE: ABC transporter, permease (IM), ISVH-family (iron siderophores, vitamin B12 and hemin); iron-siderophore ABC transporter inner membrane subunit 2956729 9795102 AARI_26350 Arthrobacter arilaitensis Re117 iron-siderophore ABC transporter inner membrane subunit YP_003917819.1 2955680 R 861360 CDS YP_003917820.1 308178414 9795103 2956750..2957550 1 NC_014550.1 identified by match to PF00753: metallo-beta- lactamase superfamily. Apart from the beta-lactamases, a number of other proteins contain this domain. These proteins include thiolesterases, members of the glyoxalase II family, that catalyse the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid and a competence protein that is essential for natural transformation in Neisseria gonorrhoeae and could be a transporter involved in DNA uptake; metallo-beta-lactamase 2957550 9795103 AARI_26360 Arthrobacter arilaitensis Re117 metallo-beta-lactamase YP_003917820.1 2956750 D 861360 CDS YP_003917821.1 308178415 9795104 complement(2957557..2958615) 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, iron chelate uptake transporter (FeCT) family (TC 3.A.1.14.z). ABCISSE: ABC transporter, binding protein (BP), ISVH- family (iron siderophores, vitamin B12 and hemin); iron-siderophore ABC transporter substrate-binding protein 2958615 9795104 AARI_26370 Arthrobacter arilaitensis Re117 iron-siderophore ABC transporter substrate-binding protein YP_003917821.1 2957557 R 861360 CDS YP_003917822.1 308178416 9795105 complement(2958806..2960131) 1 NC_014550.1 match to PF02687: this is a family of predicted permeases and hypothetical transmembrane proteins; permease 2960131 9795105 AARI_26380 Arthrobacter arilaitensis Re117 permease YP_003917822.1 2958806 R 861360 CDS YP_003917823.1 308178417 9795106 complement(2960128..2960871) 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily (TC 3. A.1.y.z). ABCISSE: ABC transporter, ATP-binding protein (ABC), o228 family (members of this family might be involved in a more general lipoprotein releasing mechanism common to all prokaryotes); ABC transporter ATP-binding subunit 2960871 9795106 AARI_26390 Arthrobacter arilaitensis Re117 ABC transporter ATP-binding subunit YP_003917823.1 2960128 R 861360 CDS YP_003917824.1 308178418 9795107 2961046..2961264 1 NC_014550.1 hypothetical protein 2961264 9795107 AARI_26400 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917824.1 2961046 D 861360 CDS YP_003917825.1 308178419 9795108 2961338..2961973 1 NC_014550.1 hypothetical protein 2961973 9795108 AARI_26410 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917825.1 2961338 D 861360 CDS YP_003917826.1 308178420 9795109 complement(2962042..2963136) 1 NC_014550.1 identified by match to PF00924: mechanosensitive ion channel. Mechanosensitive channels provide protection against hypo-osmotic shock, responding both to stretching of the cell membrane and to membrane depolarisation. Two members of this protein family: Q57634 and Q58543 of M. jannaschii have been functionally characterised. Both proteins form mechanosensitive ion channels upon reconstitution into liposomes and functional examination by the patch-clamp technique. Therefore this family are likely to also be MS channel proteins. . TC 1.A.23.y.z (Small Conductance Mechanosensitive Ion Channel (MscS) Family); MscS mechanosensitive ion channel protein 2963136 9795109 AARI_26420 Arthrobacter arilaitensis Re117 MscS mechanosensitive ion channel protein YP_003917826.1 2962042 R 861360 CDS YP_003917827.1 308178421 9795110 2963348..2963893 1 NC_014550.1 signal peptide predicted by SignalP 3.0 HMM (probability: 1.000) with cleavage site probability 0.468 between position 31 and 32; hypothetical protein 2963893 9795110 AARI_26430 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917827.1 2963348 D 861360 CDS YP_003917828.1 308178422 9795111 2963980..2964987 1 NC_014550.1 identified by match to protein family PF02567. PhzC/PhzF is involved in dimerisation of two 2, 3-dihydro-3- oxo-anthranilic acid molecules to create phenazine-1- carboxylic acid (PCA) by P. fluorescens. This family also contains a thymidilate synthase from Mycobacterium tuberculosis. Many phenazine compounds are found in nature and are produced by bacteria such as Pseudomonas spp., Streptomyces spp., and Pantoea agglomerans. These compounds have been implicated in the virulence and competitive fitness of producing organisms. For example, the phenazine pyocyanin produced by Pseudomonas aeruginosa contributes to its ability to colonise the lungs of cystic fibrosis patients. Similarly, phenazine-1-carboxylic acid, produced by a number of Pseudomonas, increases survival in soil environments and has been shown to be essential for the biological control activity of certain strains; phenazine biosynthesis protein PhzC/PhzF 2964987 9795111 AARI_26440 Arthrobacter arilaitensis Re117 phenazine biosynthesis protein PhzC/PhzF YP_003917828.1 2963980 D 861360 CDS YP_003917829.1 308178423 9795112 2965049..2966500 1 NC_014550.1 major facilitator superfamily, drug:H+ antiporter-2 (14 spanner) (DHA2) family (TC 2.A.1.3.z). Identified by match to protein family TIGR00711; EmrB/QacA subfamily drug resistance transporter 2966500 9795112 AARI_26450 Arthrobacter arilaitensis Re117 EmrB/QacA subfamily drug resistance transporter YP_003917829.1 2965049 D 861360 CDS YP_003917830.1 308178424 9795113 complement(2966580..2966771) 1 NC_014550.1 hypothetical protein 2966771 9795113 AARI_26460 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917830.1 2966580 R 861360 CDS YP_003917831.1 308178425 9795114 complement(2966876..2967307) 1 NC_014550.1 hypothetical protein 2967307 9795114 AARI_26470 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917831.1 2966876 R 861360 CDS YP_003917832.1 308178426 9795115 2967469..2968158 1 NC_014550.1 match to PF00440: bacterial regulatory proteins, tetR family; transcriptional regulator 2968158 9795115 AARI_26480 Arthrobacter arilaitensis Re117 transcriptional regulator YP_003917832.1 2967469 D 861360 CDS YP_003917833.1 308178427 9795116 2968261..2969493 1 NC_014550.1 possibly involved in the metabolism of lipids. Match to protein domains PF08028, PF02771 and PF02770. Acyl-CoA dehydrogenases catalyze the alpha,beta- dehydrogenation of acyl-CoA thioesters to the corresponding trans 2,3-enoyl CoA-products with concommitant reduction of enzyme-bound FAD; acyl-CoA dehydrogenase 2969493 9795116 AARI_26490 Arthrobacter arilaitensis Re117 acyl-CoA dehydrogenase YP_003917833.1 2968261 D 861360 CDS YP_003917834.1 308178428 9795117 complement(2969559..2972117) 1 NC_014550.1 match to protein family TIGR01970: ATP-dependent helicase HrpB; ATP-dependent RNA helicase 2972117 9795117 AARI_26500 Arthrobacter arilaitensis Re117 ATP-dependent RNA helicase YP_003917834.1 2969559 R 861360 CDS YP_003917835.1 308178429 9795118 complement(2972114..2972899) 1 NC_014550.1 match to PF00561: alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes; hydrolase 2972899 9795118 AARI_26510 Arthrobacter arilaitensis Re117 hydrolase YP_003917835.1 2972114 R 861360 CDS YP_003917836.1 308178430 9795119 2973052..2973213 1 NC_014550.1 hypothetical protein 2973213 9795119 AARI_26520 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917836.1 2973052 D 861360 CDS YP_003917837.1 308178431 9795120 2973514..2974575 1 NC_014550.1 identified by match to PF00248 family: Aldo/keto reductase family. This family includes a number of K+ ion channel beta chain regulatory domains - these are reported to have oxidoreductase activity; aldo-keto reductase family protein 2974575 9795120 AARI_26530 Arthrobacter arilaitensis Re117 aldo-keto reductase family protein YP_003917837.1 2973514 D 861360 CDS YP_003917838.1 308178432 9795121 2974848..2976230 1 NC_014550.1 succinate-semialdehyde dehydrogenase (NAD(P)(+)) reduces succinate semialdehyde into succinate. Involved in the degradation of gamma-aminobutyrate; succinate-semialdehyde dehydrogenase 2976230 gabD 9795121 gabD Arthrobacter arilaitensis Re117 succinate-semialdehyde dehydrogenase YP_003917838.1 2974848 D 861360 CDS YP_003917839.1 308178433 9793876 complement(2976332..2977264) 1 NC_014550.1 5 transmembrane helices predicted by TMHMM2.0; hypothetical protein 2977264 9793876 AARI_26550 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917839.1 2976332 R 861360 CDS YP_003917840.1 308178434 9795122 complement(2977396..2977605) 1 NC_014550.1 hypothetical protein 2977605 9795122 AARI_26560 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917840.1 2977396 R 861360 CDS YP_003917841.1 308178435 9795123 complement(2978268..2983022) 1 NC_014550.1 match to protein domain PF00746: Gram positive anchor. Surface proteins from Gram-positive cocci are covalently linked to the bacterial cell wall by sortase, a membrane-anchored transpeptidase that cleaves proteins between the threonine and the glycine of a conserved LPxTG motif, with the formation of a thioester between the conserved cysteine of sortase and the threonine carboxyl group. The newly liberated C-terminus of the threonine is transferred via an amide bond exchange to the amino group of the pentaglycine wall crossbridge, thereby tethering the C-terminus end of the surface protein to the bacterial peptidoglycan.The proteins that contain the conserved hexapeptide and hydrophobic anchor are diverse: they include M proteins, IgA and IgG binding proteins, fibronectin-binding proteins, wall-associated proteins, trypsin-resistant surface T protein, protein H precursor, etc. Signal peptide predicted by SignalP 3.0 HMM (probability: 1.000) with cleavage site probability 0.981 between position 35 and 36; cell surface protein 2983022 9795123 AARI_26570 Arthrobacter arilaitensis Re117 cell surface protein YP_003917841.1 2978268 R 861360 CDS YP_003917842.1 308178436 9795124 2983442..2984107 1 NC_014550.1 response regulators are key elements in two- component signal transduction systems, which enable bacteria to sense, respond, and adapt to a wide range of environments, stressors, and growth conditions; two-component system response regulator 2984107 9795124 AARI_26580 Arthrobacter arilaitensis Re117 two-component system response regulator YP_003917842.1 2983442 D 861360 CDS YP_003917843.1 308178437 9795125 complement(2984125..2984847) 1 NC_014550.1 match to PF08239: bacterial SH3 domain. A homologue of the SH3 domain has been found in a number of different bacterial proteins including glycyl-glycine endopeptidase, bacteriocin and some hypothetical proteins; SH3 domain-containing protein 2984847 9795125 AARI_26590 Arthrobacter arilaitensis Re117 SH3 domain-containing protein YP_003917843.1 2984125 R 861360 CDS YP_003917844.1 308178438 9795126 complement(2984939..2985439) 1 NC_014550.1 identified by match to PF00210. Ferritin is one of the major non-haem iron storage proteins in animals, plants, and microorganisms. It consists of a mineral core of hydrated ferric oxide, and a multi-subunit protein shell that encloses the former and assures its solubility in an aqueous environment; ferritin-like protein 2985439 9795126 AARI_26600 Arthrobacter arilaitensis Re117 ferritin-like protein YP_003917844.1 2984939 R 861360 CDS YP_003917845.1 308178439 9795127 complement(2985585..2988014) 1 NC_014550.1 match to protein family PTHR10724: Tex protein- related transcription accessory protein; transcriptional accessory protein 2988014 9795127 AARI_26610 Arthrobacter arilaitensis Re117 transcriptional accessory protein YP_003917845.1 2985585 R 861360 CDS YP_003917846.1 308178440 9795128 2988108..2988461 1 NC_014550.1 signal peptide predicted by SignalP 3.0 HMM (probability: 1.000) with cleavage site probability 0.877 between position 34 and 35; hypothetical protein 2988461 9795128 AARI_26620 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917846.1 2988108 D 861360 CDS YP_003917847.1 308178441 9795129 2988505..2988915 1 NC_014550.1 match to protein domain PF01479. The S4 domain was detected in proteins such as the bacterial ribosomal protein S4, two families of pseudouridine synthases, a novel family of predicted RNA methylases, a bacterial tyrosyl-tRNA synthetases, and a number of uncharacterized, small proteins that may be involved in translation regulation. The S4 domain probably mediates binding to RNA; S4 domain-containing protein 2988915 9795129 AARI_26630 Arthrobacter arilaitensis Re117 S4 domain-containing protein YP_003917847.1 2988505 D 861360 CDS YP_003917848.1 308178442 9795130 complement(2988912..2990861) 1 NC_014550.1 identified by match to protein family PF00326. Prolyl oligopeptidase family consist of a number of evolutionary related peptidases whose catalytic activity seems to be provided by a charge relay system similar to that of the trypsin family of serine proteases, but which evolved by independent convergent evolutionidentified by match to protein family PF00326. Prolyl oligopeptidase family consist of a number of evolutionary related peptidases whose catalytic activity seems to be provided by a charge relay system similar to that of the trypsin family of serine proteases, but which evolved by independent convergent evolution; prolyl oligopeptidase family protein 2990861 9795130 AARI_26640 Arthrobacter arilaitensis Re117 prolyl oligopeptidase family protein YP_003917848.1 2988912 R 861360 CDS YP_003917849.1 308178443 9795131 2990937..2991476 1 NC_014550.1 hypothetical protein 2991476 9795131 AARI_26650 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917849.1 2990937 D 861360 CDS YP_003917850.1 308178444 9795132 2991536..2992192 1 NC_014550.1 4 transmembrane helices predicted by TMHMM2.0; hypothetical protein 2992192 9795132 AARI_26660 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917850.1 2991536 D 861360 CDS YP_003917851.1 308178445 9795133 complement(2992189..2993445) 1 NC_014550.1 major facilitator superfamily (TC 2.A.1.y.z). Identified by match to protein family PF07690 (Major Facilitator Superfamily); MFS superfamily transporter 2993445 9795133 AARI_26670 Arthrobacter arilaitensis Re117 MFS superfamily transporter YP_003917851.1 2992189 R 861360 CDS YP_003917852.1 308178446 9795134 complement(2993460..2994017) 1 NC_014550.1 match to PF00440: bacterial regulatory proteins, tetR family; transcriptional regulator 2994017 9795134 AARI_26680 Arthrobacter arilaitensis Re117 transcriptional regulator YP_003917852.1 2993460 R 861360 CDS YP_003917853.1 308178447 9795135 2994150..2995667 1 NC_014550.1 major facilitator superfamily, drug:H+ antiporter-2 (14 spanner) (DHA2) family (TC 2.A.1.3.z). Identified by match to protein family TIGR00711; EmrB/QacA subfamily drug resistance transporter 2995667 9795135 AARI_26690 Arthrobacter arilaitensis Re117 EmrB/QacA subfamily drug resistance transporter YP_003917853.1 2994150 D 861360 CDS YP_003917854.1 308178448 9795136 2995962..2996165 1 NC_014550.1 match to PF00313: cold-shock DNA-binding domain. The so-called cold shock proteins are thought to help the cell to survive in temperatures lower than optimum growth temperature, by contrast with heat shock proteins, which help the cell to survive in temperatures greater than the optimum, possibly by condensation of the chromosome and organization of the prokaryotic nucleoid; cold shock protein 2996165 9795136 AARI_26700 Arthrobacter arilaitensis Re117 cold shock protein YP_003917854.1 2995962 D 861360 CDS YP_003917855.1 308178449 9795137 2996292..2997284 1 NC_014550.1 identified by match to PF00296. Bacterial luciferase is a flavin monooxygenase that catalyses the oxidation of long-chain aldehydes and releases energy in the form of visible light, and which uses flavin as a substrate rather than a cofactor. There are structural similarities between bacterial luciferase and nonfluorescent flavoproteins (LuxF, FP390), alkanesulfonate monooxygenase (SsuD), and coenzyme F420- dependent terahydromethanopterin reductase, which make up clearly related families with somewhat different folds; luciferase-like monooxygenase 2997284 9795137 AARI_26710 Arthrobacter arilaitensis Re117 luciferase-like monooxygenase YP_003917855.1 2996292 D 861360 CDS YP_003917856.1 308178450 9795138 complement(2997271..2997753) 1 NC_014550.1 4 transmembrane helices predicted by TMHMM2.0; hypothetical protein 2997753 9795138 AARI_26720 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917856.1 2997271 R 861360 CDS YP_003917857.1 308178451 9795139 complement(2997775..2999013) 1 NC_014550.1 major facilitator superfamily (TC 2.A.1.y.z). Identified by match to protein family PF07690 (Major Facilitator Superfamily); MFS superfamily transporter 2999013 9795139 AARI_26730 Arthrobacter arilaitensis Re117 MFS superfamily transporter YP_003917857.1 2997775 R 861360 CDS YP_003917858.1 308178452 9795140 2999260..2999733 1 NC_014550.1 identified by match to protein family PF01037; AsnC/Lrp family transcriptional regulator 2999733 9795140 AARI_26740 Arthrobacter arilaitensis Re117 AsnC/Lrp family transcriptional regulator YP_003917858.1 2999260 D 861360 CDS YP_003917859.1 308178453 9795141 2999869..3000132 1 NC_014550.1 hypothetical protein 3000132 9795141 AARI_26750 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917859.1 2999869 D 861360 CDS YP_003917860.1 308178454 9795142 3000178..3001083 1 NC_014550.1 identified by match to PF00126: bacterial regulatory helix-turn-helix protein, lysR family. Numerous bacterial transcription regulatory proteins bind DNA via a helix-turn-helix (HTH) motif. These proteins are very diverse, but for convenience may be grouped into subfamilies on the basis of sequence similarity. One such family, the lysR family, groups together a range of proteins, including ampR, catM, catR, cynR, cysB, gltC, iciA, ilvY, irgB, lysR, metR, mkaC, mleR, nahR, nhaR, nodD, nolR, oxyR, pssR, rbcR, syrM, tcbR, tfdS and trpI. The majority of these proteins appear to be transcription activators and most are known to negatively regulate their own expression. All possess a potential HTH DNA-binding motif towards their N-termini; LysR family transcriptional regulator 3001083 9795142 AARI_26760 Arthrobacter arilaitensis Re117 LysR family transcriptional regulator YP_003917860.1 3000178 D 861360 CDS YP_003917861.1 308178455 9795143 3001143..3002207 1 NC_014550.1 enoyl-CoA hydratase catalyzes the hydratation of 2- trans-enoyl-CoA into 3-hydroxyacyl-CoA; enoyl-CoA hydratase 3002207 9795143 AARI_26770 Arthrobacter arilaitensis Re117 enoyl-CoA hydratase YP_003917861.1 3001143 D 861360 CDS YP_003917862.1 308178456 9795145 3002731..3004038 1 NC_014550.1 transposase of ISAar19, ISL3 family 3004038 9795145 AARI_35610 Arthrobacter arilaitensis Re117 transposase of ISAar19, ISL3 family YP_003917862.1 3002731 D 861360 CDS YP_003917863.1 308178457 9795146 complement(3005487..3007247) 1 NC_014550.1 TC 3.A.1.y.z. ABCISSE: ABC transporter, permease and ATP-binding protein (IM-ABC), DPL-family; ABC transporter ATPase and permease components 3007247 9795146 AARI_26800 Arthrobacter arilaitensis Re117 ABC transporter ATPase and permease components YP_003917863.1 3005487 R 861360 CDS YP_003917864.1 308178458 9795147 complement(3007247..3008986) 1 NC_014550.1 TC 3.A.1.y.z. ABCISSE: ABC transporter, permease and ATP-binding protein (IM-ABC), DPL-family; ABC transporter ATPase and permease components 3008986 9795147 AARI_26810 Arthrobacter arilaitensis Re117 ABC transporter ATPase and permease components YP_003917864.1 3007247 R 861360 CDS YP_003917865.1 308178459 9795148 3009105..3010091 1 NC_014550.1 match to protein domain PF03061: thioesterase superfamily; thioesterase family domain-containing protein 3010091 9795148 AARI_26820 Arthrobacter arilaitensis Re117 thioesterase family domain-containing protein YP_003917865.1 3009105 D 861360 CDS YP_003917866.1 308178460 9795149 3010088..3010696 1 NC_014550.1 catalyzes the following reaction: N-(5-phospho- beta-D-ribosyl)anthranilate <=> 1-(2-carboxyphenylamino)-1- deoxy-D-ribulose 5-phosphate. Involved in tryptophane biosynthesis; phosphoribosylanthranilate isomerase 3010696 trpF 9795149 trpF Arthrobacter arilaitensis Re117 phosphoribosylanthranilate isomerase YP_003917866.1 3010088 D 861360 CDS YP_003917867.1 308178461 9794471 complement(3010801..3011346) 1 NC_014550.1 match to protein domain PF03061: thioesterase superfamily; thioesterase family domain-containing protein 3011346 9794471 AARI_26840 Arthrobacter arilaitensis Re117 thioesterase family domain-containing protein YP_003917867.1 3010801 R 861360 CDS YP_003917868.1 308178462 9795150 3011503..3012873 1 NC_014550.1 protein-histidine kinases are key elements in two- component signal transduction systems, which enable bacteria to sense, respond, and adapt to a wide range of environments, stressors, and growth conditions. 4 transmembrane helices predicted by TMHMM2.0; signal transduction histidine kinase 3012873 9795150 AARI_26850 Arthrobacter arilaitensis Re117 signal transduction histidine kinase YP_003917868.1 3011503 D 861360 CDS YP_003917869.1 308178463 9795151 3012870..3013535 1 NC_014550.1 response regulators are key elements in two- component signal transduction systems, which enable bacteria to sense, respond, and adapt to a wide range of environments, stressors, and growth conditions; two-component system response regulator 3013535 9795151 AARI_26860 Arthrobacter arilaitensis Re117 two-component system response regulator YP_003917869.1 3012870 D 861360 CDS YP_003917870.1 308178464 9795152 3013617..3014498 1 NC_014550.1 TC 3.A.1.y.z. ABCISSE: ABC transporter, ATP-binding protein (ABC), DRI-family, DRB-subfamily (drug resistance, ). Possible function in drug efflux; drug resistance ATP-binding protein 3014498 9795152 AARI_26870 Arthrobacter arilaitensis Re117 drug resistance ATP-binding protein YP_003917870.1 3013617 D 861360 CDS YP_003917871.1 308178465 9795153 3014495..3015667 1 NC_014550.1 TC 3.A.1.y.z. ABCISSE: ABC transporter, permease (IM), DRI-family, DRB-subfamily (drug resistance, ). Possible function in drug efflux; drug ABC transporter inner membrane subunit 3015667 9795153 AARI_26880 Arthrobacter arilaitensis Re117 drug ABC transporter inner membrane subunit YP_003917871.1 3014495 D 861360 CDS YP_003917872.1 308178466 9795154 3015670..3016326 1 NC_014550.1 6 transmembrane helices predicted by TMHMM2.0; hypothetical protein 3016326 9795154 AARI_26890 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917872.1 3015670 D 861360 CDS YP_003917873.1 308178467 9795155 complement(3016403..3019921) 1 NC_014550.1 proline dehydrogenase (EC 1.5.99.8) catalyses the following reaction: L-proline + acceptor + H(2)O <=> (S)-1- pyrroline-5-carboxylate + reduced acceptor. Pyrroline-5- carboxylate dehydrogenase (EC 1.5.1.12) catalyses the following reaction: 1-pyrroline-5-carboxylate + NAD(+) + H(2)O <=> L-glutamate + NADH; bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase 3019921 putA 9795155 putA Arthrobacter arilaitensis Re117 bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase YP_003917873.1 3016403 R 861360 CDS YP_003917874.1 308178468 9794260 3020157..3021131 1 NC_014550.1 identified by match to PF00126: bacterial regulatory helix-turn-helix protein, lysR family. Numerous bacterial transcription regulatory proteins bind DNA via a helix-turn-helix (HTH) motif. These proteins are very diverse, but for convenience may be grouped into subfamilies on the basis of sequence similarity. One such family, the lysR family, groups together a range of proteins, including ampR, catM, catR, cynR, cysB, gltC, iciA, ilvY, irgB, lysR, metR, mkaC, mleR, nahR, nhaR, nodD, nolR, oxyR, pssR, rbcR, syrM, tcbR, tfdS and trpI. The majority of these proteins appear to be transcription activators and most are known to negatively regulate their own expression. All possess a potential HTH DNA-binding motif towards their N-termini; LysR family transcriptional regulator 3021131 9794260 AARI_26910 Arthrobacter arilaitensis Re117 LysR family transcriptional regulator YP_003917874.1 3020157 D 861360 CDS YP_003917875.1 308178469 9795156 3021255..3022760 1 NC_014550.1 Solute:Sodium Symporter (SSS) family, Na+/proline symporter (TC 2.A.21.2.1); sodium/proline symporter 3022760 putP 9795156 putP Arthrobacter arilaitensis Re117 sodium/proline symporter YP_003917875.1 3021255 D 861360 CDS YP_003917876.1 308178470 9794261 3022933..3024336 1 NC_014550.1 identified by match to protein family PF01370: NAD dependent epimerase/dehydratase family. This family of proteins utilise NAD as a cofactor. The proteins in this family use nucleotide-sugar substrates for a variety of chemical reactions; NAD dependent epimerase/dehydratase family protein 3024336 9794261 AARI_26930 Arthrobacter arilaitensis Re117 NAD dependent epimerase/dehydratase family protein YP_003917876.1 3022933 D 861360 CDS YP_003917877.1 308178471 9795157 3024562..3026187 1 NC_014550.1 biotin carboxylase-like protein 3026187 9795157 AARI_26940 Arthrobacter arilaitensis Re117 biotin carboxylase-like protein YP_003917877.1 3024562 D 861360 CDS YP_003917878.1 308178472 9795158 3026177..3027406 1 NC_014550.1 match to protein family HMM PF00144: beta- lactamase; hypothetical protein 3027406 9795158 AARI_26950 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917878.1 3026177 D 861360 CDS YP_003917879.1 308178473 9795159 complement(3027495..3030227) 1 NC_014550.1 identified by match to PF01276: Orn/Lys/Arg decarboxylase, major domain; amino acid decarboxylase 3030227 9795159 AARI_26960 Arthrobacter arilaitensis Re117 amino acid decarboxylase YP_003917879.1 3027495 R 861360 CDS YP_003917880.1 308178474 9795161 3031273..3032580 1 NC_014550.1 transposase of ISAar19, ISL3 family 3032580 9795161 AARI_35620 Arthrobacter arilaitensis Re117 transposase of ISAar19, ISL3 family YP_003917880.1 3031273 D 861360 CDS YP_003917881.1 308178475 9795162 3033125..3033871 1 NC_014550.1 7 transmembrane helices predicted by TMHMM2.0; hypothetical protein 3033871 9795162 AARI_26990 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917881.1 3033125 D 861360 CDS YP_003917882.1 308178476 9795163 3033881..3034600 1 NC_014550.1 6 transmembrane helices predicted by TMHMM2.0; hypothetical protein 3034600 9795163 AARI_27000 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917882.1 3033881 D 861360 CDS YP_003917883.1 308178477 9795164 3034612..3035820 1 NC_014550.1 metal-dependent amidase/aminoacylase/carboxypeptidase 3035820 9795164 AARI_27010 Arthrobacter arilaitensis Re117 metal-dependent amidase/aminoacylase/carboxypeptidase YP_003917883.1 3034612 D 861360 CDS YP_003917884.1 308178478 9795165 complement(3036105..3036920) 1 NC_014550.1 match to protein family PF08282: haloacid dehalogenase-like hydrolase. The Haloacid Dehydrogenase (HAD) superfamily includes phosphatases, phosphonatases, P- type ATPases, beta-phosphoglucomutases, phosphomannomutases, and dehalogenases, which are involved in a variety of cellular processes ranging from amino acid biosynthesis to detoxification; haloacid dehalogenase-like hydrolase 3036920 9795165 AARI_27020 Arthrobacter arilaitensis Re117 haloacid dehalogenase-like hydrolase YP_003917884.1 3036105 R 861360 CDS YP_003917885.1 308178479 9795166 complement(3036928..3037737) 1 NC_014550.1 catalyzes the following reaction: (phosphate)(n) + D-glucose <=> (phosphate)(n-1) + D-glucose 6-phosphate. The polyphosphate-glucose phosphotransferase isolated from the Gram-positive bacterium Arthrobacter sp. strain KM, is a monomer that phosphorylates glucose and mannose with preference for glucose through the use of poly(P) and ATP; polyphosphate-glucose phosphotransferase 3037737 ppgK 9795166 ppgK Arthrobacter arilaitensis Re117 polyphosphate-glucose phosphotransferase YP_003917885.1 3036928 R 861360 CDS YP_003917886.1 308178480 9794216 complement(3037809..3038873) 1 NC_014550.1 transcriptional regulator 3038873 9794216 AARI_27040 Arthrobacter arilaitensis Re117 transcriptional regulator YP_003917886.1 3037809 R 861360 CDS YP_003917887.1 308178481 9795948 complement(3038906..3040003) 1 NC_014550.1 catalyses the following reaction: an alcohol + NAD(+) <=> an aldehyde or ketone + NADH; Zn-dependent alcohol dehydrogenase 3040003 9795948 AARI_27050 Arthrobacter arilaitensis Re117 Zn-dependent alcohol dehydrogenase YP_003917887.1 3038906 R 861360 CDS YP_003917888.1 308178482 9795949 complement(3040006..3040950) 1 NC_014550.1 catalyzes the NAD-dependent, reversible oxidation of 3-hydroxbutyrate to methylmalonate. Involved in the catabolism of valine; 3-hydroxyisobutyrate dehydrogenase 3040950 mmsB 9795949 mmsB Arthrobacter arilaitensis Re117 3-hydroxyisobutyrate dehydrogenase YP_003917888.1 3040006 R 861360 CDS YP_003917889.1 308178483 9794084 3041092..3042021 1 NC_014550.1 identified by match to PF00126: bacterial regulatory helix-turn-helix protein, lysR family. Numerous bacterial transcription regulatory proteins bind DNA via a helix-turn-helix (HTH) motif. These proteins are very diverse, but for convenience may be grouped into subfamilies on the basis of sequence similarity. One such family, the lysR family, groups together a range of proteins, including ampR, catM, catR, cynR, cysB, gltC, iciA, ilvY, irgB, lysR, metR, mkaC, mleR, nahR, nhaR, nodD, nolR, oxyR, pssR, rbcR, syrM, tcbR, tfdS and trpI. The majority of these proteins appear to be transcription activators and most are known to negatively regulate their own expression. All possess a potential HTH DNA-binding motif towards their N-termini; LysR family transcriptional regulator 3042021 9794084 AARI_27070 Arthrobacter arilaitensis Re117 LysR family transcriptional regulator YP_003917889.1 3041092 D 861360 CDS YP_003917890.1 308178484 9795950 complement(3042029..3042580) 1 NC_014550.1 signal peptide predicted by SignalP 3.0 HMM (probability: 0.574) with cleavage site probability 0.495 between position 29 and 30; hypothetical protein 3042580 9795950 AARI_27080 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917890.1 3042029 R 861360 CDS YP_003917891.1 308178485 9795951 complement(3042807..3044186) 1 NC_014550.1 major facilitator superfamily (MFS), metabolite:H+ symporter (MHS) family (TC 2.A.1.6.z); MFS superfamily transporter 3044186 9795951 AARI_27090 Arthrobacter arilaitensis Re117 MFS superfamily transporter YP_003917891.1 3042807 R 861360 CDS YP_003917892.1 308178486 9795952 3044358..3044711 1 NC_014550.1 match to PF05495: CHY zinc finger. This family of domains are likely to bind to zinc ions; zinc finger domain-containing protein 3044711 9795952 AARI_27100 Arthrobacter arilaitensis Re117 zinc finger domain-containing protein YP_003917892.1 3044358 D 861360 CDS YP_003917893.1 308178487 9795953 complement(3044708..3045157) 1 NC_014550.1 identified by match to PF00582: universal stress protein family. The universal stress protein UspA is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. UspA enhances the rate of cell survival during prolonged exposure to such conditions, and may provide a general stress endurance activity; universal stress family domain-containing protein 3045157 9795953 AARI_27110 Arthrobacter arilaitensis Re117 universal stress family domain-containing protein YP_003917893.1 3044708 R 861360 CDS YP_003917894.1 308178488 9795954 complement(3045205..3046416) 1 NC_014550.1 match to PF07992: pyridine nucleotide-disulphide oxidoreductase. This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases; oxidoreductase 3046416 9795954 AARI_27120 Arthrobacter arilaitensis Re117 oxidoreductase YP_003917894.1 3045205 R 861360 CDS YP_003917895.1 308178489 9795955 complement(3046537..3048420) 1 NC_014550.1 identified by similarity to protein SP:P54417 (Bacillus subtilis). betaine/carnitine/choline transporter (BCCT) family, glycine betaine:H+ symporter (TC 2.A.15.1. 1). High-affinity uptake of glycine betaine; glycine betaine transporter 3048420 opuD 9795955 opuD Arthrobacter arilaitensis Re117 glycine betaine transporter YP_003917895.1 3046537 R 861360 CDS YP_003917896.1 308178490 9794158 3048678..3049859 1 NC_014550.1 identified by match to PF00082. Subtilases are a family of serine proteases. The vast majority of the family are endopeptidases; subtilase family protease 3049859 9794158 AARI_27140 Arthrobacter arilaitensis Re117 subtilase family protease YP_003917896.1 3048678 D 861360 CDS YP_003917897.1 308178491 9795956 3049864..3050097 1 NC_014550.1 hypothetical protein 3050097 9795956 AARI_27150 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917897.1 3049864 D 861360 CDS YP_003917898.1 308178492 9795957 complement(3050094..3050954) 1 NC_014550.1 catalyses the following reaction: 10- formyltetrahydrofolate + H(2)O <=> formate + tetrahydrofolate; formyltetrahydrofolate deformylase 3050954 purU 9795957 purU Arthrobacter arilaitensis Re117 formyltetrahydrofolate deformylase YP_003917898.1 3050094 R 861360 CDS YP_003917899.1 308178493 9794258 complement(3051135..3051743) 1 NC_014550.1 sarcosine oxidase catalyzes the oxidative demethylation of sarcosine and forms equimolar amounts of formaldehyde, glycine and hydrogen peroxide; heterotetrameric sarcosine oxidase subunit gamma 3051743 soxG 9794258 soxG Arthrobacter arilaitensis Re117 heterotetrameric sarcosine oxidase subunit gamma YP_003917899.1 3051135 R 861360 CDS YP_003917900.1 308178494 9794403 complement(3051736..3054633) 1 NC_014550.1 sarcosine oxidase catalyzes the oxidative demethylation of sarcosine and forms equimolar amounts of formaldehyde, glycine and hydrogen peroxide; heterotetrameric sarcosine oxidase subunit alpha 3054633 soxA 9794403 soxA Arthrobacter arilaitensis Re117 heterotetrameric sarcosine oxidase subunit alpha YP_003917900.1 3051736 R 861360 CDS YP_003917901.1 308178495 9794400 complement(3054630..3054929) 1 NC_014550.1 sarcosine oxidase catalyzes the oxidative demethylation of sarcosine and forms equimolar amounts of formaldehyde, glycine and hydrogen peroxide; heterotetrameric sarcosine oxidase subunit delta 3054929 soxD 9794400 soxD Arthrobacter arilaitensis Re117 heterotetrameric sarcosine oxidase subunit delta YP_003917901.1 3054630 R 861360 CDS YP_003917902.1 308178496 9794402 complement(3054941..3056158) 1 NC_014550.1 sarcosine oxidase catalyzes the oxidative demethylation of sarcosine and forms equimolar amounts of formaldehyde, glycine and hydrogen peroxide; heterotetrameric sarcosine oxidase subunit beta 3056158 soxB 9794402 soxB Arthrobacter arilaitensis Re117 heterotetrameric sarcosine oxidase subunit beta YP_003917902.1 3054941 R 861360 CDS YP_003917903.1 308178497 9794401 complement(3056161..3057477) 1 NC_014550.1 catalyzes the transfer of the hydroxymethyl group of serine to tetrahydrofolate to form 5,10- methylenetetrahydrofolate and glycine. Also catalyzes the reaction of glycine with acetaldehyde to form L-threonine; glycine hydroxymethyltransferase 3057477 glyA 9794401 glyA Arthrobacter arilaitensis Re117 glycine hydroxymethyltransferase YP_003917903.1 3056161 R 861360 CDS YP_003917904.1 308178498 9793927 3057629..3058288 1 NC_014550.1 identified by match to protein family PF00392. This family of regulatory proteins consists of the N-terminal HTH region of GntR-like bacterial transcription factors. At the C-terminus there is usually an effector- binding/oligomerisation domain. The GntR-like proteins can be divided into six sub-families: MocR, YtrR, FadR, AraR, HutC and PlmA. Many of these proteins have been shown experimentally to be autoregulatory, enabling the prediction of operator sites and the discovery of cis/trans relationships; GntR family transcriptional regulator 3058288 9793927 AARI_27220 Arthrobacter arilaitensis Re117 GntR family transcriptional regulator YP_003917904.1 3057629 D 861360 CDS YP_003917905.1 308178499 9795958 3058700..3059494 1 NC_014550.1 creatininase catalyses the formation of creatine from creatinine; creatininase 3059494 9795958 AARI_27230 Arthrobacter arilaitensis Re117 creatininase YP_003917905.1 3058700 D 861360 CDS YP_003917906.1 308178500 9795959 3059538..3061241 1 NC_014550.1 identified by similarity to protein SP:P54417 (Bacillus subtilis). betaine/carnitine/choline transporter (BCCT) family, glycine betaine:H+ symporter (TC 2.A.15.1. 1). High-affinity uptake of glycine betaine; glycine betaine transporter 3061241 opuD 9795959 opuD Arthrobacter arilaitensis Re117 glycine betaine transporter YP_003917906.1 3059538 D 861360 CDS YP_003917907.1 308178501 9794159 3061538..3062791 1 NC_014550.1 hydrolyzes creatine to sarcosine and urea; creatinase 3062791 9794159 AARI_27250 Arthrobacter arilaitensis Re117 creatinase YP_003917907.1 3061538 D 861360 CDS YP_003917908.1 308178502 9795960 3062985..3064325 1 NC_014550.1 identified by similarity to protein SP:P0C0L7 (Escherichia coli). Proton symporter that senses osmotic shifts and responds by importing osmolytes such as proline, glycine betaine, stachydrine, pipecolic acid, ectoine and taurine. It is both an osmosensor and an osmoregulator which is available to participate early in the bacterial osmoregulatory response. Metabolite:H+ symporter (MHS) family, (Poline/glycine-betaine):(H+/Na+) symporter (also transports taurine, ectoine, pipecolate, proline-betaine, N,N-dimethylglycine, carnitine, and 1- carboxymethyl-pyridinium) (subject to osmotic activation) (TC 2.A.1.6.4); proline/betaine transporter 3064325 proP 9795960 proP Arthrobacter arilaitensis Re117 proline/betaine transporter YP_003917908.1 3062985 D 861360 CDS YP_003917909.1 308178503 9794228 3064357..3065130 1 NC_014550.1 identified by match to PF09339: IclR helix-turn- helix domain. This family of bacterial transcriptional regulators groups several proteins, including gylR, a possible activator protein for the gylABX glycerol operon in Streptomyces, and iclR, the repressor of the acetate operon (also known as glyoxylate bypass operon) in Escherichia coli and Salmonella typhimurium; IclR family transcriptional regulator 3065130 9794228 AARI_27270 Arthrobacter arilaitensis Re117 IclR family transcriptional regulator YP_003917909.1 3064357 D 861360 CDS YP_003917910.1 308178504 9795961 3065133..3065549 1 NC_014550.1 presence of one conserved barrel domain of the cupin superfamily (PF07883); hypothetical protein 3065549 9795961 AARI_27280 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917910.1 3065133 D 861360 CDS YP_003917911.1 308178505 9795962 3065606..3066193 1 NC_014550.1 identified by match to PF03358. FMN reductase reductase catalyses the following reaction: NAD(P)H + FMN = NAD(P)(+) + FMNH(2); FMN reductase 3066193 9795962 AARI_27290 Arthrobacter arilaitensis Re117 FMN reductase YP_003917911.1 3065606 D 861360 CDS YP_003917912.1 308178506 9795963 complement(3066439..3067263) 1 NC_014550.1 match to PF04434: SWIM zinc finger. SWIM is thought to be a versatile domain that can interact with DNA or proteins in different contexts; zinc finger domain-containing protein 3067263 9795963 AARI_27300 Arthrobacter arilaitensis Re117 zinc finger domain-containing protein YP_003917912.1 3066439 R 861360 CDS YP_003917913.1 308178507 9795964 complement(3067256..3070405) 1 NC_014550.1 possible DNA or RNA helicase; ATP-dependent helicase 3070405 9795964 AARI_27310 Arthrobacter arilaitensis Re117 ATP-dependent helicase YP_003917913.1 3067256 R 861360 CDS YP_003917914.1 308178508 9793644 3070873..3071298 1 NC_014550.1 identified by match to PF00903: glyoxalase/bleomycin resistance protein/dioxygenase superfamily; glyoxalase family protein 3071298 9793644 AARI_27320 Arthrobacter arilaitensis Re117 glyoxalase family protein YP_003917914.1 3070873 D 861360 CDS YP_003917915.1 308178509 9795966 complement(3071309..3072535) 1 NC_014550.1 drug:H+ antiporter-1 (12 Spanner) (DHA1) family transporter (TC 2.A.1.2.z). Match to PR01035 (Tetracycline resistance protein signature); multidrug efflux permease 3072535 9795966 AARI_27330 Arthrobacter arilaitensis Re117 multidrug efflux permease YP_003917915.1 3071309 R 861360 CDS YP_003917916.1 308178510 9795967 3072681..3073622 1 NC_014550.1 3 transmembrane helices predicted by TMHMM2.0; hypothetical protein 3073622 9795967 AARI_27340 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917916.1 3072681 D 861360 CDS YP_003917917.1 308178511 9795968 complement(3073619..3074293) 1 NC_014550.1 identified by match to PF03171. This family contains members of the 2-oxoglutarate (2OG) and Fe(II)- dependent oxygenase superfamily; 2OG-Fe(II) oxygenase superfamily protein 3074293 9795968 AARI_27350 Arthrobacter arilaitensis Re117 2OG-Fe(II) oxygenase superfamily protein YP_003917917.1 3073619 R 861360 CDS YP_003917918.1 308178512 9795969 3074585..3075604 1 NC_014550.1 catalyzes two sequential methylation reactions, the first forming precorrin-1 and the second leading to the formation of precorrin-2 (dihydrosirohydrochlorin): (1) S- adenosyl-L-methionine + uroporphyrinogen III <=> S- adenosyl-L-homocysteine + precorrin-1, (2) S-adenosyl-L- methionine + precorrin-1 <=> S-adenosyl-L-homocysteine + precorrin-2; uroporphyrinogen-III C-methyltransferase 3075604 cobA 9795969 cobA Arthrobacter arilaitensis Re117 uroporphyrinogen-III C-methyltransferase YP_003917918.1 3074585 D 861360 CDS YP_003917919.1 308178513 9793752 3075604..3076704 1 NC_014550.1 uroporphyrinogen-III synthase catalyses the following reaction: hydroxymethylbilane <=> uroporphyrinogen III + H(2)O. Possible fusion with a response regulator domain protein; uroporphyrinogen-III synthase 3076704 hemD 9793752 hemD Arthrobacter arilaitensis Re117 uroporphyrinogen-III synthase YP_003917919.1 3075604 D 861360 CDS YP_003917920.1 308178514 9793952 3076751..3077659 1 NC_014550.1 fructokinase catalyzes the conversion of fructose to fructose-6-phosphate, which is an entry point into glycolysis via conversion into glucose-6-phosphate; fructokinase 3077659 9793952 AARI_27380 Arthrobacter arilaitensis Re117 fructokinase YP_003917920.1 3076751 D 861360 CDS YP_003917921.1 308178515 9795970 3077980..3078753 1 NC_014550.1 identified by match to PF09339: IclR helix-turn- helix domain. This family of bacterial transcriptional regulators groups several proteins, including gylR, a possible activator protein for the gylABX glycerol operon in Streptomyces, and iclR, the repressor of the acetate operon (also known as glyoxylate bypass operon) in Escherichia coli and Salmonella typhimurium; IclR family transcriptional regulator 3078753 9795970 AARI_27390 Arthrobacter arilaitensis Re117 IclR family transcriptional regulator YP_003917921.1 3077980 D 861360 CDS YP_003917922.1 308178516 9795971 complement(3078765..3079796) 1 NC_014550.1 match to protein domain PF01261: xylose isomerase- like TIM barrel . This TIM alpha/beta barrel structure is found in xylose isomerase and in endonuclease IV (EC.1.21. 2). This domain is also found in the N termini of bacterial myo-inositol catabolism proteins; xylose isomerase-like protein 3079796 9795971 AARI_27400 Arthrobacter arilaitensis Re117 xylose isomerase-like protein YP_003917922.1 3078765 R 861360 CDS YP_003917923.1 308178517 9795972 complement(3079789..3080895) 1 NC_014550.1 identified by match to PF01408 (oxidoreductase family, NAD-binding Rossmann fold) and PF02894 (oxidoreductase family, C-terminal alpha/beta domain); oxidoreductase domain-containing protein 3080895 9795972 AARI_27410 Arthrobacter arilaitensis Re117 oxidoreductase domain-containing protein YP_003917923.1 3079789 R 861360 CDS YP_003917924.1 308178518 9795974 complement(3081198..3082310) 1 NC_014550.1 identified by match to PF01408 (oxidoreductase family, NAD-binding Rossmann fold); oxidoreductase domain-containing protein 3082310 9795974 AARI_27430 Arthrobacter arilaitensis Re117 oxidoreductase domain-containing protein YP_003917924.1 3081198 R 861360 CDS YP_003917925.1 308178519 9795975 complement(3082316..3083056) 1 NC_014550.1 match to protein domain PF01261: xylose isomerase- like TIM barrel. This TIM alpha/beta barrel structure is found in xylose isomerase and in endonuclease IV (EC.1.21. 2). This domain is also found in the N termini of bacterial myo-inositol catabolism proteins; xylose isomerase-like protein 3083056 9795975 AARI_27440 Arthrobacter arilaitensis Re117 xylose isomerase-like protein YP_003917925.1 3082316 R 861360 CDS YP_003917926.1 308178520 9795976 3083215..3084429 1 NC_014550.1 identified by match to PF00480: ROK family; transcriptional regulator 3084429 9795976 AARI_27450 Arthrobacter arilaitensis Re117 transcriptional regulator YP_003917926.1 3083215 D 861360 CDS YP_003917927.1 308178521 9795977 3084560..3086236 1 NC_014550.1 catalyzes the second step in the degradation of histidine, the hydration of urocanate into imidazolonepropionate; urocanate hydratase 3086236 hutU 9795977 hutU Arthrobacter arilaitensis Re117 urocanate hydratase YP_003917927.1 3084560 D 861360 CDS YP_003917928.1 308178522 9793994 complement(3086316..3086825) 1 NC_014550.1 DPS (DNA Protecting protein under Starved conditions) domain is a member of a broad superfamily of ferritin-like diiron-carboxylate proteins. Some DPS proteins nonspecifically bind DNA, protecting it from cleavage caused by reactive oxygen species such as the hydroxyl radicals produced during oxidation of Fe(II) by hydrogen peroxide. These proteins assemble into dodecameric structures, some form DPS-DNA co-crystalline complexes, and possess iron and H2O2 detoxification capabilities. Expression of DPS is induced by oxidative or nutritional stress, including metal ion starvation; DPS family protein 3086825 9793994 AARI_27470 Arthrobacter arilaitensis Re117 DPS family protein YP_003917928.1 3086316 R 861360 CDS YP_003917929.1 308178523 9795978 3087295..3087525 1 NC_014550.1 hypothetical protein 3087525 9795978 AARI_27480 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917929.1 3087295 D 861360 CDS YP_003917930.1 308178524 9795979 3087902..3088516 1 NC_014550.1 signal peptide predicted by SignalP 3.0 HMM (probability: 0.991) with cleavage site probability 0.786 between position 45 and 46; hypothetical protein 3088516 9795979 AARI_27490 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917930.1 3087902 D 861360 CDS YP_003917931.1 308178525 9795980 3088698..3090239 1 NC_014550.1 catalyzes the first step in histidine degradation, the removal of an ammonia group from histidine to produce urocanic acid; histidine ammonia-lyase 3090239 hutH 9795980 hutH Arthrobacter arilaitensis Re117 histidine ammonia-lyase YP_003917931.1 3088698 D 861360 CDS YP_003917932.1 308178526 9793991 3090349..3090771 1 NC_014550.1 step in the major route of beta-alanine production for pantothenate biosynthesis in bacteria; aspartate 1-decarboxylase 3090771 panD 9793991 panD Arthrobacter arilaitensis Re117 aspartate 1-decarboxylase YP_003917932.1 3090349 D 861360 CDS YP_003917933.1 308178527 9794175 complement(3090780..3093236) 1 NC_014550.1 excinuclease ABC catalyses nucleotide excision repair in a multi-step process; excinuclease ABC subunit A 3093236 uvrA 9794175 uvrA Arthrobacter arilaitensis Re117 excinuclease ABC subunit A YP_003917933.1 3090780 R 861360 CDS YP_003917934.1 308178528 9794497 complement(3093291..3093659) 1 NC_014550.1 hypothetical protein 3093659 9794497 AARI_27530 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917934.1 3093291 R 861360 CDS YP_003917935.1 308178529 9795981 3093830..3094312 1 NC_014550.1 4 transmembrane helices predicted by TMHMM2.0; hypothetical protein 3094312 9795981 AARI_27540 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917935.1 3093830 D 861360 CDS YP_003917936.1 308178530 9795982 complement(3094324..3095124) 1 NC_014550.1 hypothetical protein 3095124 9795982 AARI_27550 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917936.1 3094324 R 861360 CDS YP_003917937.1 308178531 9795983 complement(3095267..3095650) 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, carbohydrate uptake transporter-2 (CUT2) family (TC 3.A.1. 2.z). ABCISSE: ABCISSE: ABC transporter, permease (IM), MOS-family (monosaccharides: pentoses and hexoses), ribose import; ribose ABC transporter inner membrane subunit 3095650 9795983 AARI_27560 Arthrobacter arilaitensis Re117 ribose ABC transporter inner membrane subunit YP_003917937.1 3095267 R 861360 CDS YP_003917938.1 308178532 9795984 complement(3095686..3096588) 1 NC_014550.1 catalyses the phosphorylation of ribose to ribose-5- phosphate. 2-deoxy-D-ribose can also act as acceptor; ribokinase 3096588 rbsK 9795984 rbsK Arthrobacter arilaitensis Re117 ribokinase YP_003917938.1 3095686 R 861360 CDS YP_003917939.1 308178533 9795986 complement(3097696..3098730) 1 NC_014550.1 match to protein domain PF00356. Numerous bacterial transcription regulatory proteins bind DNA via a helix- turn-helix (HTH) motif. These proteins are very diverse, but for convenience may be grouped into subfamilies on the basis of sequence similarity. One such family groups together a range of proteins, including ascG, ccpA, cytR, ebgR, fruR, galR, galS, lacI, malI, opnR, purF, rafR, rbtR and scrR. Within this family, the HTH motif is situated towards the N-terminus; LacI family transcriptional regulator 3098730 9795986 AARI_27600 Arthrobacter arilaitensis Re117 LacI family transcriptional regulator YP_003917939.1 3097696 R 861360 CDS YP_003917940.1 308178534 9795987 3098993..3099670 1 NC_014550.1 identified by match to PF01325, PF02742 and PF04023. The diphtheria toxin repressor protein (DTXR) is a member of this group. In Corynebacterium diphtheriae where it has been studied in some detail this protein acts as an iron-binding repressor of dipheteria toxin gene expression and may serve as a global regulator of gene expression. The N-terminus may be involved in iron binding and may associate with the Tox operator. Binding of DTXR to Tox operator requires a divalent metal ion such as cobalt, ferric, manganese and nickel whereas zinc shows weak activation; metal-dependent transcriptional regulator 3099670 9795987 AARI_27610 Arthrobacter arilaitensis Re117 metal-dependent transcriptional regulator YP_003917940.1 3098993 D 861360 CDS YP_003917941.1 308178535 9795988 3099870..3100832 1 NC_014550.1 signal peptide predicted by SignalP 3.0 HMM (probability: 1.000) with cleavage site probability 0.312 between position 36 and 37; hypothetical protein 3100832 9795988 AARI_27620 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917941.1 3099870 D 861360 CDS YP_003917942.1 308178536 9795989 complement(3100890..3101765) 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, Manganese/Zinc/Iron Chelate Uptake Transporter (MZT) Family (TC 3.A.1.15.z). ABCISSE: ABC transporter, permease (IM), MET-family, manganese uptake. Identified by similarity to protein SP:Q55282 (Synechocystis sp.); manganese ABC transporter inner membrane subunit MntB 3101765 mntB 9795989 mntB Arthrobacter arilaitensis Re117 manganese ABC transporter inner membrane subunit MntB YP_003917942.1 3100890 R 861360 CDS YP_003917943.1 308178537 9794092 complement(3101762..3102517) 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, Manganese/Zinc/Iron Chelate Uptake Transporter (MZT) Family (TC 3.A.1.15.z). ABCISSE: ABC transporter, ATP- binding protein (ABC), MET-family, manganese uptake. Identified by similarity to protein SP:Q55281 (Synechocystis sp.); manganese ABC transporter ATP-binding protein MntA 3102517 mntA 9794092 mntA Arthrobacter arilaitensis Re117 manganese ABC transporter ATP-binding protein MntA YP_003917943.1 3101762 R 861360 CDS YP_003917944.1 308178538 9794091 complement(3102514..3103455) 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, Manganese/Zinc/Iron Chelate Uptake Transporter (MZT) Family (TC 3.A.1.15.z). ABCISSE: ABC transporter, binding protein (BP), MET-family, manganese uptake. Identified by similarity to protein SP:Q55280 (Synechocystis sp.); manganese ABC transporter substrate-binding protein MntC 3103455 mntC 9794091 mntC Arthrobacter arilaitensis Re117 manganese ABC transporter substrate-binding protein MntC YP_003917944.1 3102514 R 861360 CDS YP_003917945.1 308178539 9794093 complement(3103588..3104544) 1 NC_014550.1 hydrolyzes N-formimino-glutamate into glutamate and formamide; formimidoylglutamase 3104544 hutG 9794093 hutG Arthrobacter arilaitensis Re117 formimidoylglutamase YP_003917945.1 3103588 R 861360 CDS YP_003917946.1 308178540 9793990 complement(3104632..3105285) 1 NC_014550.1 hypothetical protein 3105285 9793990 AARI_27670 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917946.1 3104632 R 861360 CDS YP_003917947.1 308178541 9795992 complement(3106512..3106859) 1 NC_014550.1 hypothetical protein 3106859 9795992 AARI_27700 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917947.1 3106512 R 861360 CDS YP_003917948.1 308178542 9795993 3107106..3107792 1 NC_014550.1 identified by match to PF09339: IclR helix-turn- helix domain. This family of bacterial transcriptional regulators groups several proteins, including gylR, a possible activator protein for the gylABX glycerol operon in Streptomyces, and iclR, the repressor of the acetate operon (also known as glyoxylate bypass operon) in Escherichia coli and Salmonella typhimurium; IclR family transcriptional regulator 3107792 9795993 AARI_27710 Arthrobacter arilaitensis Re117 IclR family transcriptional regulator YP_003917948.1 3107106 D 861360 CDS YP_003917949.1 308178543 9795995 complement(3108604..3109413) 1 NC_014550.1 8 transmembrane helices predicted by TMHMM2.0; hypothetical protein 3109413 9795995 AARI_27730 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917949.1 3108604 R 861360 CDS YP_003917950.1 308178544 9795996 3109915..3110706 1 NC_014550.1 identified by match to PF00376 and PF09278. Members of the family include the mercuric resistance operon regulatory protein merR; Bacillus subtilis bltR and bmrR; Bacillus glnR; Streptomyces coelicolor hspR; Bradyrhizobium japonicum nolA; Escherichia coli superoxide response regulator soxR; and Streptomyces lividans transcriptional activator tipA; MerR family transcriptional regulator 3110706 9795996 AARI_27740 Arthrobacter arilaitensis Re117 MerR family transcriptional regulator YP_003917950.1 3109915 D 861360 CDS YP_003917951.1 308178545 9795997 complement(3110725..3110907) 1 NC_014550.1 match to PF00376: MerR family regulatory protein; DNA-binding protein 3110907 9795997 AARI_27750 Arthrobacter arilaitensis Re117 DNA-binding protein YP_003917951.1 3110725 R 861360 CDS YP_003917952.1 308178546 9795998 3111158..3111640 1 NC_014550.1 identified by match to protein family PF01037; AsnC/Lrp family transcriptional regulator 3111640 9795998 AARI_27760 Arthrobacter arilaitensis Re117 AsnC/Lrp family transcriptional regulator YP_003917952.1 3111158 D 861360 CDS YP_003917953.1 308178547 9795999 complement(3111717..3112778) 1 NC_014550.1 major facilitator superfamily (TC 2.A.1.y.z). Identified by match to protein family PF07690 (Major Facilitator Superfamily); MFS superfamily transporter 3112778 9795999 AARI_27770 Arthrobacter arilaitensis Re117 MFS superfamily transporter YP_003917953.1 3111717 R 861360 CDS YP_003917954.1 308178548 9796000 complement(3112925..3113329) 1 NC_014550.1 identified by match to protein family PF01451. Protein tyrosine (pTyr) phosphorylation is a common post- translational modification which can create novel recognition motifs for protein interactions and cellular localisation, affect protein stability, and regulate enzyme activity. Consequently, maintaining an appropriate level of protein tyrosine phosphorylation is essential for many cellular functions. Tyrosine-specific protein phosphatases (PTPase; EC:3.1.3.48) catalyse the removal of a phosphate group attached to a tyrosine residue, using a cysteinyl-phosphate enzyme intermediate. These enzymes are key regulatory components in signal transduction pathways (such as the MAP kinase pathway) and cell cycle control, and are important in the control of cell growth, proliferation, differentiation and transformation. Low molecular weight (LMW) protein-tyrosine phosphatases (or acid phosphatase) act on tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates; low molecular weight protein-tyrosine-phosphatase 3113329 9796000 AARI_27780 Arthrobacter arilaitensis Re117 low molecular weight protein-tyrosine-phosphatase YP_003917954.1 3112925 R 861360 CDS YP_003917955.1 308178549 9796001 complement(3113484..3115007) 1 NC_014550.1 amino acid-polyamine-organocation (APC) superfamily (TC 2.A.3.y.z); amino acid transporter 3115007 9796001 AARI_27790 Arthrobacter arilaitensis Re117 amino acid transporter YP_003917955.1 3113484 R 861360 CDS YP_003917956.1 308178550 9796002 complement(3115159..3116031) 1 NC_014550.1 identified by match to PF00582: universal stress protein family. The universal stress protein UspA is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. UspA enhances the rate of cell survival during prolonged exposure to such conditions, and may provide a general stress endurance activity; universal stress protein 3116031 9796002 AARI_27800 Arthrobacter arilaitensis Re117 universal stress protein YP_003917956.1 3115159 R 861360 CDS YP_003917957.1 308178551 9796003 complement(3116035..3117462) 1 NC_014550.1 catalyses the following reaction: putrescine + O(2) + H(2)O <=> 4-aminobutanal + NH(3) + H(2)O(2); putrescine oxidase 3117462 puo 9796003 puo Arthrobacter arilaitensis Re117 putrescine oxidase YP_003917957.1 3116035 R 861360 CDS YP_003917958.1 308178552 9794243 3117569..3118216 1 NC_014550.1 identified by match to PF00440: bacterial regulatory proteins, tetR family; TetR family transcriptional regulator 3118216 9794243 AARI_27820 Arthrobacter arilaitensis Re117 TetR family transcriptional regulator YP_003917958.1 3117569 D 861360 CDS YP_003917959.1 308178553 9796004 3118213..3118443 1 NC_014550.1 2 transmembrane helices predicted by TMHMM2.0; hypothetical protein 3118443 9796004 AARI_27830 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917959.1 3118213 D 861360 CDS YP_003917960.1 308178554 9796005 complement(3118440..3118628) 1 NC_014550.1 hypothetical protein 3118628 9796005 AARI_27840 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917960.1 3118440 R 861360 CDS YP_003917961.1 308178555 9796006 complement(3118790..3119161) 1 NC_014550.1 1 transmembrane helice predicted by TMHMM2.0; hypothetical protein 3119161 9796006 AARI_27850 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917961.1 3118790 R 861360 CDS YP_003917962.1 308178556 9796007 complement(3119516..3119761) 1 NC_014550.1 1 transmembrane helice predicted by TMHMM2.0; hypothetical protein 3119761 9796007 AARI_27860 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917962.1 3119516 R 861360 CDS YP_003917963.1 308178557 9796008 complement(3119961..3120449) 1 NC_014550.1 identified by match to protein family PF01037; AsnC/Lrp family transcriptional regulator 3120449 9796008 AARI_27870 Arthrobacter arilaitensis Re117 AsnC/Lrp family transcriptional regulator YP_003917963.1 3119961 R 861360 CDS YP_003917964.1 308178558 9796009 complement(3120446..3121015) 1 NC_014550.1 3 transmembrane helices predicted by TMHMM2.0; hypothetical protein 3121015 9796009 AARI_27880 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917964.1 3120446 R 861360 CDS YP_003917965.1 308178559 9796010 complement(3121018..3122274) 1 NC_014550.1 major facilitator superfamily (TC 2.A.1.y.z). Identified by match to protein family PF07690 (Major Facilitator Superfamily); MFS superfamily transporter 3122274 9796010 AARI_27890 Arthrobacter arilaitensis Re117 MFS superfamily transporter YP_003917965.1 3121018 R 861360 CDS YP_003917966.1 308178560 9796011 complement(3122282..3123415) 1 NC_014550.1 3-phenylpropionate dioxygenase converts 3- phenylpropionic acid (PP) into cis-3-(3-carboxyethyl)-3,5- cyclohexadiene-1,2-diol (PP-dihydrodiol). Involved in the catabolism of 3-phenylpropionic acid; 3-phenylpropionate dioxygenase ferredoxin reductase subunit 3123415 9796011 AARI_27900 Arthrobacter arilaitensis Re117 3-phenylpropionate dioxygenase ferredoxin reductase subunit YP_003917966.1 3122282 R 861360 CDS YP_003917967.1 308178561 9796012 complement(3123416..3123733) 1 NC_014550.1 identified by similarity to SP:P0ABW0. Part of multicomponent 3-phenylpropionate dioxygenase, that converts 3-phenylpropionic acid (PP) into cis-3-(3- carboxyethyl)-3,5-cyclohexadiene-1,2-diol (PP- dihydrodiol). Involved in the catabolism of 3- phenylpropionic acid; 3-phenylpropionate dioxygenase ferredoxin subunit 3123733 hcaC 9796012 hcaC Arthrobacter arilaitensis Re117 3-phenylpropionate dioxygenase ferredoxin subunit YP_003917967.1 3123416 R 861360 CDS YP_003917968.1 308178562 9793947 complement(3123829..3124758) 1 NC_014550.1 match to PF01869: BadF/BadG/BcrA/BcrD ATPase family. This family includes the BadF and BadG proteins that are two subunits of Benzoyl-CoA reductase, that may be involved in ATP hydrolysis. The family also includes an activase subunit from the enzyme 2-hydroxyglutaryl-CoA dehydratase; ATPase domain-containing protein 3124758 9793947 AARI_27920 Arthrobacter arilaitensis Re117 ATPase domain-containing protein YP_003917968.1 3123829 R 861360 CDS YP_003917969.1 308178563 9796013 3125365..3127314 1 NC_014550.1 identified by match to PF00082. Subtilases are a family of serine proteases. The vast majority of the family are endopeptidases. Signal peptide predicted by SignalP 3.0 HMM (probability: 1.000) with cleavage site probability 0.991 between position 34 and 35; subtilase 3127314 9796013 AARI_27930 Arthrobacter arilaitensis Re117 subtilase YP_003917969.1 3125365 D 861360 CDS YP_003917970.1 308178564 9796014 complement(3127413..3129203) 1 NC_014550.1 match to protein family PF02652. Lactate Permease (LctP) Family (TC 2.A.14.y.z). Members of this family are involved in the uptake of L-lactate, D-lactate and glycolate; lactate permease 3129203 9796014 AARI_27940 Arthrobacter arilaitensis Re117 lactate permease YP_003917970.1 3127413 R 861360 CDS YP_003917971.1 308178565 9796015 complement(3129569..3130366) 1 NC_014550.1 identified by match to protein family PF02900. Dioxygenases catalyse the incorporation of both atoms of molecular oxygen into substrates using a variety of reaction mechanisms. Cleavage of aromatic rings is one of the most important functions of dioxygenases, which play key roles in the degradation of aromatic compounds; aromatic ring-opening dioxygenase catalytic subunit 3130366 9796015 AARI_27950 Arthrobacter arilaitensis Re117 aromatic ring-opening dioxygenase catalytic subunit YP_003917971.1 3129569 R 861360 CDS YP_003917972.1 308178566 9796016 3130869..3131312 1 NC_014550.1 identified by match to protein family PF01047. Regulators with the marR-type HTH domain are present in bacteria and archaea and control a variety of biological functions, including resistance to multiple antibiotics, household disinfectants, organic solvents, oxidative stress agents and regulation of the virulence factor synthesis in pathogens of humans and plants. Many of the marR-like regulators respond to aromatic compounds; MarR family transcriptional regulator 3131312 9796016 AARI_27960 Arthrobacter arilaitensis Re117 MarR family transcriptional regulator YP_003917972.1 3130869 D 861360 CDS YP_003917973.1 308178567 9796017 complement(3131378..3134593) 1 NC_014550.1 possible DNA or RNA helicase; ATP-dependent helicase 3134593 9796017 AARI_27970 Arthrobacter arilaitensis Re117 ATP-dependent helicase YP_003917973.1 3131378 R 861360 CDS YP_003917974.1 308178568 9796018 3134885..3135436 1 NC_014550.1 identified by match to protein family PF02566: OsmC, OsmC-like protein. Osmotically inducible protein C (OsmC) is a stress-induced protein found in Escherichia coli. This family also contains an organic hydroperoxide detoxification protein that has a novel pattern of oxidative stress regulation; OsmC-like protein 3135436 9796018 AARI_27980 Arthrobacter arilaitensis Re117 OsmC-like protein YP_003917974.1 3134885 D 861360 CDS YP_003917975.1 308178569 9796019 complement(3135518..3136546) 1 NC_014550.1 L-idonate 5-dehydrogenase catalyzes the NADH/NADPH- dependent oxidation of L-idonate to 5-ketogluconate. It is involved in L-idonic acid degradation; L-idonate 5-dehydrogenase 3136546 idnD 9796019 idnD Arthrobacter arilaitensis Re117 L-idonate 5-dehydrogenase YP_003917975.1 3135518 R 861360 CDS YP_003917976.1 308178570 9793999 complement(3136560..3137330) 1 NC_014550.1 catalyzes a reversible reduction of 5-ketoglutanate to form D-gluconate; gluconate 5-dehydrogenase 3137330 idnO 9793999 idnO Arthrobacter arilaitensis Re117 gluconate 5-dehydrogenase YP_003917976.1 3136560 R 861360 CDS YP_003917977.1 308178571 9794000 complement(3137502..3138209) 1 NC_014550.1 identified by match to protein family PF00392. This family of regulatory proteins consists of the N-terminal HTH region of GntR-like bacterial transcription factors. At the C-terminus there is usually an effector- binding/oligomerisation domain. The GntR-like proteins can be divided into six sub-families: MocR, YtrR, FadR, AraR, HutC and PlmA. Many of these proteins have been shown experimentally to be autoregulatory, enabling the prediction of operator sites and the discovery of cis/trans relationships; GntR family transcriptional regulator 3138209 9794000 AARI_28010 Arthrobacter arilaitensis Re117 GntR family transcriptional regulator YP_003917977.1 3137502 R 861360 CDS YP_003917978.1 308178572 9796020 complement(3138234..3139910) 1 NC_014550.1 match to protein family PF02652. Lactate Permease (LctP) Family (TC 2.A.14.y.z). Members of this family are involved in the uptake of L-lactate, D-lactate and glycolate; lactate permease 3139910 9796020 AARI_28020 Arthrobacter arilaitensis Re117 lactate permease YP_003917978.1 3138234 R 861360 CDS YP_003917979.1 308178573 9796021 3140057..3140821 1 NC_014550.1 identified by match to PF02754. This domain is usually found in two copies per protein. It contains up to four conserved cysteines. The group includes proteins characterised as: heterodisulphide reductase, subunit B (HrdB); succinate dehydrogenase, subunit C (SdhC ); Fe-S oxidoreductase; glycerol-3-phosphate dehydrogenase subunit C (Anaerobic GlpC, ); and glycolate oxidase iron-sulfur subunit (GlcF); cysteine-rich domain-containing protein 3140821 9796021 AARI_28030 Arthrobacter arilaitensis Re117 cysteine-rich domain-containing protein YP_003917979.1 3140057 D 861360 CDS YP_003917980.1 308178574 9796022 3140839..3142290 1 NC_014550.1 identified by match to protein family TIGR00273; iron-sulfur cluster binding protein 3142290 9796022 AARI_28040 Arthrobacter arilaitensis Re117 iron-sulfur cluster binding protein YP_003917980.1 3140839 D 861360 CDS YP_003917981.1 308178575 9796023 3142287..3142919 1 NC_014550.1 hypothetical protein 3142919 9796023 AARI_28050 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917981.1 3142287 D 861360 CDS YP_003917982.1 308178576 9796024 3143119..3144297 1 NC_014550.1 major facilitator superfamily (TC 2.A.1.y.z). Identified by match to protein family PF07690 (Major Facilitator Superfamily); MFS superfamily transporter 3144297 9796024 AARI_28060 Arthrobacter arilaitensis Re117 MFS superfamily transporter YP_003917982.1 3143119 D 861360 CDS YP_003917983.1 308178577 9796025 3144423..3144869 1 NC_014550.1 2 transmembrane helices predicted by TMHMM2.0; hypothetical protein 3144869 9796025 AARI_28070 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917983.1 3144423 D 861360 CDS YP_003917984.1 308178578 9796026 complement(3145008..3145550) 1 NC_014550.1 identified by match to protein family PF04264. This entry represents the lipid-binding protein YceI from Escherichia coli and the polyisoprenoid-binding protein TTHA0802 from Thermus thermophilus. The crystal structures of Yce1 and TTHA0802 suggest that this family of proteins plays an important role in isoprenoid quinone metabolism and/or transport and/or storage; YceI family protein 3145550 9796026 AARI_28080 Arthrobacter arilaitensis Re117 YceI family protein YP_003917984.1 3145008 R 861360 CDS YP_003917985.1 308178579 9796027 3145770..3145928 1 NC_014550.1 hypothetical protein 3145928 9796027 AARI_28090 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917985.1 3145770 D 861360 CDS YP_003917986.1 308178580 9796028 complement(3146081..3147058) 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, quaternary amine uptake transporter (QAT) family (TC 3.A.1. 12.z). ABCISSE: ABC transporter, binding protein (BP), OTCN-family (osmoprotectants, taurine, cyanate and nitrate). Part of an uptake system of osmoprotrectants such as glycine betaine, carnitine, choline, proline betaine and L-proline; osmoprotectant (glycine betaine/carnitine/choline/L-proline) ABC transporter substrate-binding protein 3147058 9796028 AARI_28100 Arthrobacter arilaitensis Re117 osmoprotectant (glycine betaine/carnitine/choline/L-proline) ABC transporter substrate-binding protein YP_003917986.1 3146081 R 861360 CDS YP_003917987.1 308178581 9796110 complement(3147055..3147783) 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, quaternary amine uptake transporter (QAT) family (TC 3.A.1. 12.z). ABCISSE: ABC transporter, permease (IM), OTCN- family (osmoprotectants, taurine, cyanate and nitrate). Part of an uptake system of osmoprotrectants such as glycine betaine, carnitine, choline, proline betaine and L- proline; osmoprotectant (glycine betaine/carnitine/choline/L-proline) ABC transporter inner membrane subunit 3147783 9796110 AARI_28110 Arthrobacter arilaitensis Re117 osmoprotectant (glycine betaine/carnitine/choline/L-proline) ABC transporter inner membrane subunit YP_003917987.1 3147055 R 861360 CDS YP_003917988.1 308178582 9796111 complement(3147780..3149042) 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, quaternary amine uptake transporter (QAT) family (TC 3.A.1. 12.z). ABCISSE: ABC transporter, ATP-binding protein (ABC), OTCN-family (osmoprotectants, taurine, cyanate and nitrate). Part of an uptake system of osmoprotrectants such as glycine betaine, carnitine, choline, proline betaine and L-proline; osmoprotectant (glycine betaine/carnitine/choline/L-proline) ABC transporter ATP-binding subunit 3149042 9796111 AARI_28120 Arthrobacter arilaitensis Re117 osmoprotectant (glycine betaine/carnitine/choline/L-proline) ABC transporter ATP-binding subunit YP_003917988.1 3147780 R 861360 CDS YP_003917989.1 308178583 9796112 complement(3149035..3149676) 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, quaternary amine uptake transporter (QAT) family (TC 3.A.1. 12.z). ABCISSE: ABC transporter, permease (IM), OTCN- family (osmoprotectants, taurine, cyanate and nitrate). Part of an uptake system of osmoprotrectants such as glycine betaine, carnitine, choline, proline betaine and L- proline; osmoprotectant (glycine betaine/carnitine/choline/L-proline) ABC transporter inner membrane subunit 3149676 9796112 AARI_28130 Arthrobacter arilaitensis Re117 osmoprotectant (glycine betaine/carnitine/choline/L-proline) ABC transporter inner membrane subunit YP_003917989.1 3149035 R 861360 CDS YP_003917990.1 308178584 9796113 3149896..3150753 1 NC_014550.1 fumarylacetoacetate hydrolase family protein 3150753 9796113 AARI_28140 Arthrobacter arilaitensis Re117 fumarylacetoacetate hydrolase family protein YP_003917990.1 3149896 D 861360 CDS YP_003917991.1 308178585 9796114 3150864..3151925 1 NC_014550.1 match to PF07683: Cobalamin synthesis protein cobW C-terminal domain; CobW domain-containing protein 3151925 9796114 AARI_28150 Arthrobacter arilaitensis Re117 CobW domain-containing protein YP_003917991.1 3150864 D 861360 CDS YP_003917992.1 308178586 9796115 3152265..3153755 1 NC_014550.1 Alanine or Glycine:Cation Symporter (AGCS) Family (TC 2.A.25.y.z). Members of the AGCS family transport alanine and/or glycine in symport with Na+ and or H+; alanine transporter 3153755 9796115 AARI_28160 Arthrobacter arilaitensis Re117 alanine transporter YP_003917992.1 3152265 D 861360 CDS YP_003917993.1 308178587 9796116 complement(3153842..3154687) 1 NC_014550.1 citrate lyase catalyses the formation of acetate and oxaloacetate from citrate; citrate lyase beta subunit 3154687 9796116 AARI_28170 Arthrobacter arilaitensis Re117 citrate lyase beta subunit YP_003917993.1 3153842 R 861360 CDS YP_003917994.1 308178588 9796117 3155301..3156782 1 NC_014550.1 amino acid-polyamine-organocation (APC) superfamily, amino acid transporter (AAT) family, D- Serine/D-alanine/glycine:H+ symporter (TC 2.A.3.1.7). Identified by similarity to protein SP:P0AAE0 (Escherichia coli); D-serine/D-alanine/glycine transporter 3156782 cycA 9796117 cycA Arthrobacter arilaitensis Re117 D-serine/D-alanine/glycine transporter YP_003917994.1 3155301 D 861360 CDS YP_003917995.1 308178589 9793769 complement(3156807..3157235) 1 NC_014550.1 hypothetical protein 3157235 9793769 AARI_28190 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917995.1 3156807 R 861360 CDS YP_003917996.1 308178590 9796118 complement(3157267..3157731) 1 NC_014550.1 hypothetical protein 3157731 9796118 AARI_28200 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917996.1 3157267 R 861360 CDS YP_003917997.1 308178591 9796119 complement(3157905..3159080) 1 NC_014550.1 catalyzes the oxidative decarboxylation of malate into pyruvate. Uses preferentially NAD and has the ability to decarboxylate oxaloacetate; malate dehydrogenase (oxaloacetate-decarboxylating) 3159080 9796119 AARI_28210 Arthrobacter arilaitensis Re117 malate dehydrogenase (oxaloacetate-decarboxylating) YP_003917997.1 3157905 R 861360 CDS YP_003917998.1 308178592 9796120 3159462..3159851 1 NC_014550.1 match to PF00376: MerR family regulatory protein; DNA-binding protein 3159851 9796120 AARI_28220 Arthrobacter arilaitensis Re117 DNA-binding protein YP_003917998.1 3159462 D 861360 CDS YP_003917999.1 308178593 9796121 3159848..3160705 1 NC_014550.1 3 transmembrane helices predicted by TMHMM2.0; hypothetical protein 3160705 9796121 AARI_28230 Arthrobacter arilaitensis Re117 hypothetical protein YP_003917999.1 3159848 D 861360 CDS YP_003918000.1 308178594 9796122 3160859..3162094 1 NC_014550.1 identified by match to PF00155: aminotransferase class I and II; aminotransferase 3162094 9796122 AARI_28240 Arthrobacter arilaitensis Re117 aminotransferase YP_003918000.1 3160859 D 861360 CDS YP_003918001.1 308178595 9796123 complement(3162191..3163123) 1 NC_014550.1 identified by match to PF00126: bacterial regulatory helix-turn-helix protein, lysR family. Numerous bacterial transcription regulatory proteins bind DNA via a helix-turn-helix (HTH) motif. These proteins are very diverse, but for convenience may be grouped into subfamilies on the basis of sequence similarity. One such family, the lysR family, groups together a range of proteins, including ampR, catM, catR, cynR, cysB, gltC, iciA, ilvY, irgB, lysR, metR, mkaC, mleR, nahR, nhaR, nodD, nolR, oxyR, pssR, rbcR, syrM, tcbR, tfdS and trpI. The majority of these proteins appear to be transcription activators and most are known to negatively regulate their own expression. All possess a potential HTH DNA-binding motif towards their N-termini; LysR family transcriptional regulator 3163123 9796123 AARI_28250 Arthrobacter arilaitensis Re117 LysR family transcriptional regulator YP_003918001.1 3162191 R 861360 CDS YP_003918002.1 308178596 9796124 3163196..3164254 1 NC_014550.1 8 transmembrane helices predicted by TMHMM2.0; hypothetical protein 3164254 9796124 AARI_28260 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918002.1 3163196 D 861360 CDS YP_003918003.1 308178597 9796125 complement(3164292..3165071) 1 NC_014550.1 3-hydroxybutyrate dehydrogenase catalyzes the following reaction: (R)-3-hydroxybutanoate + NAD+ = acetoacetate + NADH. It may be involved in the catabolism of the intracellular carbon storage compound poly-3- hydroxybutyrate; 3-hydroxybutyrate dehydrogenase 3165071 bdhA 9796125 bdhA Arthrobacter arilaitensis Re117 3-hydroxybutyrate dehydrogenase YP_003918003.1 3164292 R 861360 CDS YP_003918004.1 308178598 9793710 3165308..3166012 1 NC_014550.1 identified by match to PF00293. Members of the Nudix hydrolase superfamily catalyze the hydrolysis of nucleoside diphosphates linked to other moieties. Substrates of nudix hydrolases include intact and oxidatively damaged nucleoside triphosphates, dinucleoside polyphosphates, nucleotide-sugars and dinucleotide enzymes. These substrates are metabolites or cell signaling molecules that require regulation during different stages of the cell cycle or during periods of stress. In general, the role of the nudix hydrolase is to sanitize the nucleotide pools and to maintain cell viability, thereby serving as surveillance and house- cleaning enzymes; NUDIX hydrolase 3166012 9793710 AARI_28280 Arthrobacter arilaitensis Re117 NUDIX hydrolase YP_003918004.1 3165308 D 861360 CDS YP_003918005.1 308178599 9796126 complement(3166024..3167160) 1 NC_014550.1 possibly involved in the metabolism of lipids. Match to protein domains PF08028, PF02771 and PF02770. Acyl-CoA dehydrogenases catalyze the alpha,beta- dehydrogenation of acyl-CoA thioesters to the corresponding trans 2,3-enoyl CoA-products with concommitant reduction of enzyme-bound FAD; acyl-CoA dehydrogenase 3167160 9796126 AARI_28290 Arthrobacter arilaitensis Re117 acyl-CoA dehydrogenase YP_003918005.1 3166024 R 861360 CDS YP_003918006.1 308178600 9796127 3167281..3167790 1 NC_014550.1 identified by match to PF00583: acetyltransferase (GNAT) family; GNAT family acetyltransferase 3167790 9796127 AARI_28300 Arthrobacter arilaitensis Re117 GNAT family acetyltransferase YP_003918006.1 3167281 D 861360 CDS YP_003918007.1 308178601 9796128 complement(3167787..3168155) 1 NC_014550.1 identified by match to PF01638: HxlR-like helix- turn-helix; transcriptional regulator 3168155 9796128 AARI_28310 Arthrobacter arilaitensis Re117 transcriptional regulator YP_003918007.1 3167787 R 861360 CDS YP_003918008.1 308178602 9796129 3168241..3168849 1 NC_014550.1 hypothetical protein 3168849 9796129 AARI_28320 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918008.1 3168241 D 861360 CDS YP_003918009.1 308178603 9796130 3168981..3170645 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, peptide/opine/nickel uptake transporter (PepT) family (TC 3.A.1.5.z). ABCISSE: ABC transporter, binding protein (BP), OPN-family (oligopeptides and nickel), oligopeptides import; dipeptide/oligopeptide ABC transporter substrate-binding protein 3170645 9796130 AARI_28330 Arthrobacter arilaitensis Re117 dipeptide/oligopeptide ABC transporter substrate-binding protein YP_003918009.1 3168981 D 861360 CDS YP_003918010.1 308178604 9796131 3170652..3171584 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, peptide/opine/nickel uptake transporter (PepT) family (TC 3.A.1.5.z). ABCISSE: ABC transporter, permease (IM), OPN- family (oligopeptides and nickel), oligopeptides import; dipeptide/oligopeptide ABC transporter inner membrane subunit 3171584 9796131 AARI_28340 Arthrobacter arilaitensis Re117 dipeptide/oligopeptide ABC transporter inner membrane subunit YP_003918010.1 3170652 D 861360 CDS YP_003918011.1 308178605 9796132 3171581..3172378 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, peptide/opine/nickel uptake transporter (PepT) family (TC 3.A.1.5.z). ABCISSE: ABC transporter, permease (IM), OPN- family (oligopeptides and nickel), oligopeptides import; dipeptide/oligopeptide ABC transporter inner membrane subunit 3172378 9796132 AARI_28350 Arthrobacter arilaitensis Re117 dipeptide/oligopeptide ABC transporter inner membrane subunit YP_003918011.1 3171581 D 861360 CDS YP_003918012.1 308178606 9796133 3172375..3173970 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, peptide/opine/nickel uptake transporter (PepT) family (TC 3.A.1.5.z). ABCISSE: ABC transporter, fused ATP-binding protein (ABC2), OPN-family (oligopeptides and nickel), oligopeptides import; dipeptide/oligopeptide ABC transporter ATP-binding subunit 3173970 9796133 AARI_28360 Arthrobacter arilaitensis Re117 dipeptide/oligopeptide ABC transporter ATP-binding subunit YP_003918012.1 3172375 D 861360 CDS YP_003918013.1 308178607 9796134 complement(3174074..3174862) 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily (TC 3. A.1.y.z). ABCISSE: ABC transporter, ATP-binding protein (ABC), OTCN-family (osmoprotectants, taurine, cyanate and nitrate); ABC transporter ATP-binding subunit 3174862 9796134 AARI_28370 Arthrobacter arilaitensis Re117 ABC transporter ATP-binding subunit YP_003918013.1 3174074 R 861360 CDS YP_003918014.1 308178608 9796140 complement(3176557..3178245) 1 NC_014550.1 activates fatty acids by binding to coenzyme A. Possibly involved in the synthesis of cellular lipids or their degradation via beta-oxidation; fatty-acid--CoA ligase 3178245 9796140 AARI_28430 Arthrobacter arilaitensis Re117 fatty-acid--CoA ligase YP_003918014.1 3176557 R 861360 CDS YP_003918015.1 308178609 9796141 3178317..3180071 1 NC_014550.1 hypothetical protein 3180071 9796141 AARI_28440 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918015.1 3178317 D 861360 CDS YP_003918016.1 308178610 9796142 complement(3180068..3181168) 1 NC_014550.1 match to PF01168: Alanine racemase, N-terminal domain; alanine racemase-like protein 3181168 9796142 AARI_28450 Arthrobacter arilaitensis Re117 alanine racemase-like protein YP_003918016.1 3180068 R 861360 CDS YP_003918017.1 308178611 9796143 complement(3181278..3182114) 1 NC_014550.1 identified by match to PF09339: IclR helix-turn- helix domain. This family of bacterial transcriptional regulators groups several proteins, including gylR, a possible activator protein for the gylABX glycerol operon in Streptomyces, and iclR, the repressor of the acetate operon (also known as glyoxylate bypass operon) in Escherichia coli and Salmonella typhimurium; IclR family transcriptional regulator 3182114 9796143 AARI_28460 Arthrobacter arilaitensis Re117 IclR family transcriptional regulator YP_003918017.1 3181278 R 861360 CDS YP_003918018.1 308178612 9796144 3182170..3182625 1 NC_014550.1 hypothetical protein 3182625 9796144 AARI_28470 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918018.1 3182170 D 861360 CDS YP_003918019.1 308178613 9796145 3182790..3183494 1 NC_014550.1 oxoacid CoA-transferase catalyses the following reaction: succinyl-CoA + a 3-oxo acid <=> succinate + a 3- oxoacyl-CoA. Acetoacetate or, more slowly, 3- oxopropanoate, 3-oxopentanoate, 3-oxo-4-methylpentanoate or 3-oxohexanoate can act as acceptor; 3-oxoacid CoA-transferase subunit A 3183494 scoA 9796145 scoA Arthrobacter arilaitensis Re117 3-oxoacid CoA-transferase subunit A YP_003918019.1 3182790 D 861360 CDS YP_003918020.1 308178614 9794376 3183497..3184147 1 NC_014550.1 3-oxoacid CoA-transferase catalyses the following reaction: succinyl-CoA + a 3-oxo acid <=> succinate + a 3- oxoacyl-CoA. Acetoacetate or, more slowly, 3- oxopropanoate, 3-oxopentanoate, 3-oxo-4-methylpentanoate or 3-oxohexanoate can act as acceptor; 3-oxoacid CoA-transferase subunit B 3184147 scoB 9794376 scoB Arthrobacter arilaitensis Re117 3-oxoacid CoA-transferase subunit B YP_003918020.1 3183497 D 861360 CDS YP_003918021.1 308178615 9794377 3184144..3185313 1 NC_014550.1 catalyses the following reaction: 2 acetyl-CoA <=> CoA + acetoacetyl-CoA; acetyl-CoA C-acetyltransferase 3185313 9794377 AARI_28500 Arthrobacter arilaitensis Re117 acetyl-CoA C-acetyltransferase YP_003918021.1 3184144 D 861360 CDS YP_003918022.1 308178616 9796146 3185551..3188031 1 NC_014550.1 11 transmembrane helices predicted by TMHMM2.0; hypothetical protein 3188031 9796146 AARI_28510 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918022.1 3185551 D 861360 CDS YP_003918023.1 308178617 9796147 complement(3188129..3188689) 1 NC_014550.1 identified by match to protein domain PF00300; phosphoglycerate mutase family protein 3188689 9796147 AARI_28520 Arthrobacter arilaitensis Re117 phosphoglycerate mutase family protein YP_003918023.1 3188129 R 861360 CDS YP_003918024.1 308178618 9796148 complement(3188754..3189584) 1 NC_014550.1 identified by match to PF00149. The metallo- phosphoesterase motif is found in a large number of proteins invoved in phosphorylation. These include Ser/Thr phosphatases, DNA polymerase, exonucleases, and other phosphatases; phosphoesterase 3189584 9796148 AARI_28530 Arthrobacter arilaitensis Re117 phosphoesterase YP_003918024.1 3188754 R 861360 CDS YP_003918025.1 308178619 9796149 3189832..3190782 1 NC_014550.1 catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; beta-ketoacyl-ACP synthase III 3190782 fabH 9796149 fabH Arthrobacter arilaitensis Re117 beta-ketoacyl-ACP synthase III YP_003918025.1 3189832 D 861360 CDS YP_003918026.1 308178620 9796151 3192244..3192681 1 NC_014550.1 hypothetical protein 3192681 9796151 AARI_28570 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918026.1 3192244 D 861360 CDS YP_003918027.1 308178621 9796152 3192819..3193523 1 NC_014550.1 GntR family transcriptional regulator 3193523 9796152 AARI_28580 Arthrobacter arilaitensis Re117 GntR family transcriptional regulator YP_003918027.1 3192819 D 861360 CDS YP_003918028.1 308178622 9796153 3193520..3194515 1 NC_014550.1 catalyses the hydrolysis of L-asparagine to L- aspartate and ammonium; L-asparaginase 3194515 ansA 9796153 ansA Arthrobacter arilaitensis Re117 L-asparaginase YP_003918028.1 3193520 D 861360 CDS YP_003918029.1 308178623 9793666 3194560..3195975 1 NC_014550.1 catalyzes the reversible conversion of aspartate to fumarate and ammonia; aspartate ammonia-lyase 3195975 aspA 9793666 aspA Arthrobacter arilaitensis Re117 aspartate ammonia-lyase YP_003918029.1 3194560 D 861360 CDS YP_003918030.1 308178624 9796155 complement(3197555..3198358) 1 NC_014550.1 match to PS51257: prokaryotic membrane lipoprotein lipid attachment site profile; hypothetical protein 3198358 9796155 AARI_28630 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918030.1 3197555 R 861360 CDS YP_003918031.1 308178625 9796156 3198564..3200621 1 NC_014550.1 identified by match to protein family PF00326. Prolyl oligopeptidase family consist of a number of evolutionary related peptidases whose catalytic activity seems to be provided by a charge relay system similar to that of the trypsin family of serine proteases, but which evolved by independent convergent evolution; prolyl oligopeptidase family protein 3200621 9796156 AARI_28640 Arthrobacter arilaitensis Re117 prolyl oligopeptidase family protein YP_003918031.1 3198564 D 861360 CDS YP_003918032.1 308178626 9796157 complement(3200628..3203162) 1 NC_014550.1 signal peptide predicted by SignalP 3.0 HMM (probability: 1.000) with cleavage site probability 0.485 between position 41 and 42. 3 transmembrane helices predicted by TMHMM2.0 after the signal peptide; hypothetical protein 3203162 9796157 AARI_28650 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918032.1 3200628 R 861360 CDS YP_003918033.1 308178627 9796158 complement(3203174..3204631) 1 NC_014550.1 signal peptide predicted by SignalP 3.0 HMM (probability: 1.000) with cleavage site probability 0.702 between position 38 and 39. 1 transmembrane helice predicted by TMHMM2.0 after the signal peptide; hypothetical protein 3204631 9796158 AARI_28660 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918033.1 3203174 R 861360 CDS YP_003918034.1 308178628 9796159 complement(3204691..3205587) 1 NC_014550.1 match to protein family TIGR02937. Sigma-70 family; RNA polymerase sigma factor 3205587 9796159 AARI_28670 Arthrobacter arilaitensis Re117 RNA polymerase sigma factor YP_003918034.1 3204691 R 861360 CDS YP_003918035.1 308178629 9796160 complement(3205587..3206027) 1 NC_014550.1 hypothetical protein 3206027 9796160 AARI_28680 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918035.1 3205587 R 861360 CDS YP_003918036.1 308178630 9796161 complement(3206162..3207577) 1 NC_014550.1 possible component of pyruvate dehydrogenase (EC 2. 3.1.12), branched-chain alpha-ketoacid dehydrogenase (EC 2. 3.1.168) or 2-oxoglutarate dehydrogenase (EC 2.3.1.61) complexes; 2-oxoacid dehydrogenase E2 component 3207577 9796161 AARI_28690 Arthrobacter arilaitensis Re117 2-oxoacid dehydrogenase E2 component YP_003918036.1 3206162 R 861360 CDS YP_003918037.1 308178631 9796162 complement(3207599..3208576) 1 NC_014550.1 possible component of pyruvate dehydrogenase (EC 2. 3.1.12), branched-chain alpha-ketoacid dehydrogenase (EC 2. 3.1.168) or 2-oxoglutarate dehydrogenase (EC 2.3.1.61) complexes; 2-oxoacid dehydrogenase E1 component subunit beta 3208576 9796162 AARI_28700 Arthrobacter arilaitensis Re117 2-oxoacid dehydrogenase E1 component subunit beta YP_003918037.1 3207599 R 861360 CDS YP_003918038.1 308178632 9796163 complement(3208577..3209719) 1 NC_014550.1 possible component of pyruvate dehydrogenase (EC 2. 3.1.12), branched-chain alpha-ketoacid dehydrogenase (EC 2. 3.1.168) or 2-oxoglutarate dehydrogenase (EC 2.3.1.61) complexes; 2-oxoacid dehydrogenase E1 component subunit alpha 3209719 9796163 AARI_28710 Arthrobacter arilaitensis Re117 2-oxoacid dehydrogenase E1 component subunit alpha YP_003918038.1 3208577 R 861360 CDS YP_003918039.1 308178633 9796164 complement(3209847..3210956) 1 NC_014550.1 may catalyze the transamination reaction in phenylalanine biosynthesis; phenylalanine aminotransferase 3210956 pat 9796164 pat Arthrobacter arilaitensis Re117 phenylalanine aminotransferase YP_003918039.1 3209847 R 861360 CDS YP_003918040.1 308178634 9794179 3211039..3211425 1 NC_014550.1 4 transmembrane helices predicted by TMHMM2.0; hypothetical protein 3211425 9794179 AARI_28730 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918040.1 3211039 D 861360 CDS YP_003918041.1 308178635 9796165 complement(3211587..3212936) 1 NC_014550.1 hypothetical protein 3212936 9796165 AARI_28740 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918041.1 3211587 R 861360 CDS YP_003918042.1 308178636 9796166 complement(3212939..3213211) 1 NC_014550.1 hypothetical protein 3213211 9796166 AARI_28750 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918042.1 3212939 R 861360 CDS YP_003918043.1 308178637 9796167 3213351..3214760 1 NC_014550.1 catalyzes the eight step in the de novo biosynthesis of purines, the formation of 5-phosphoribosyl- 5-amino-4-imidazolecarboxamide and fumarate from 1-(5- phosphoribosyl)-4-(N-succino-carboxamide). Also catalyzes the formation of fumarate and AMP from adenylosuccinate; adenylosuccinate lyase 3214760 purB 9796167 purB Arthrobacter arilaitensis Re117 adenylosuccinate lyase YP_003918043.1 3213351 D 861360 CDS YP_003918044.1 308178638 9794245 complement(3214945..3215709) 1 NC_014550.1 1 transmembrane helice predicted by TMHMM2.0; hypothetical protein 3215709 9794245 AARI_28770 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918044.1 3214945 R 861360 CDS YP_003918045.1 308178639 9796168 complement(3215837..3216655) 1 NC_014550.1 identified by match to PF02625. XdhC is believed to be involved in the attachment of molybdenum to Xanthine Dehydrogenase; xanthine dehydrogenase accessory protein XdhC 3216655 xdhC 9796168 xdhC Arthrobacter arilaitensis Re117 xanthine dehydrogenase accessory protein XdhC YP_003918045.1 3215837 R 861360 CDS YP_003918046.1 308178640 9794506 complement(3216658..3218991) 1 NC_014550.1 xanthine dehydrogenase catalyses the formation of xanthine from hypoxanthine and of urate from xanthine. It is involved in purine degradation; xanthine dehydrogenase, molybdopterin-binding subunit 3218991 xdhB 9794506 xdhB Arthrobacter arilaitensis Re117 xanthine dehydrogenase, molybdopterin-binding subunit YP_003918046.1 3216658 R 861360 CDS YP_003918047.1 308178641 9794505 complement(3218988..3220493) 1 NC_014550.1 xanthine dehydrogenase catalyses the formation of xanthine from hypoxanthine and of urate from xanthine. It is involved in purine degradation; xanthine dehydrogenase, iron-sulfur and FAD-binding subunit 3220493 xdhA 9794505 xdhA Arthrobacter arilaitensis Re117 xanthine dehydrogenase, iron-sulfur and FAD-binding subunit YP_003918047.1 3218988 R 861360 CDS YP_003918048.1 308178642 9794504 complement(3220490..3220696) 1 NC_014550.1 hypothetical protein 3220696 9794504 AARI_28810 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918048.1 3220490 R 861360 CDS YP_003918049.1 308178643 9796169 complement(3220766..3222268) 1 NC_014550.1 AzgA family purine transporter (TC 2.A.1.40.z). Possibly involved in transport of compounds such as hypoxanthine, adenine, guanine, guanosine and urate; purine transporter 3222268 9796169 AARI_28820 Arthrobacter arilaitensis Re117 purine transporter YP_003918049.1 3220766 R 861360 CDS YP_003918050.1 308178644 9796172 3223204..3224613 1 NC_014550.1 Nitrate/Nitrite Porter (NNP) family (TC 2.A.1.8.z); nitrate/nitrite transporter 3224613 9796172 AARI_28850 Arthrobacter arilaitensis Re117 nitrate/nitrite transporter YP_003918050.1 3223204 D 861360 CDS YP_003918051.1 308178645 9796173 3224615..3226750 1 NC_014550.1 possible flavoprotein that may act as electron donnor in the assimilatory nitrite reductase. EC 1.7.1.4 catalyses the following reaction: ammonium hydroxide + 3 NAD(P)(+) + H(2)O <=> nitrite + 3 NAD(P)H; nitrite reductase (NAD(P)H) subunit 3226750 9796173 AARI_28860 Arthrobacter arilaitensis Re117 nitrite reductase (NAD(P)H) subunit YP_003918051.1 3224615 D 861360 CDS YP_003918052.1 308178646 9796174 3226747..3228237 1 NC_014550.1 the assimilatory nitrite reductase catalyses the following reaction: ammonium hydroxide + 3 NAD(P)(+) + H(2)O <=> nitrite + 3 NAD(P)H; nitrite reductase (NAD(P)H) subunit 3228237 9796174 AARI_28870 Arthrobacter arilaitensis Re117 nitrite reductase (NAD(P)H) subunit YP_003918052.1 3226747 D 861360 CDS YP_003918053.1 308178647 9796175 complement(3228421..3228864) 1 NC_014550.1 hypothetical protein 3228864 9796175 AARI_28880 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918053.1 3228421 R 861360 CDS YP_003918054.1 308178648 9796176 complement(3229093..3229191) 1 NC_014550.1 hypothetical protein 3229191 9796176 AARI_28890 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918054.1 3229093 R 861360 CDS YP_003918055.1 308178649 9796177 complement(3229188..3229565) 1 NC_014550.1 the assimilatory nitrite reductase catalyses the following reaction: ammonium hydroxide + 3 NAD(P)(+) + H(2)O <=> nitrite + 3 NAD(P)H. NirD contains a single Rieske [2Fe-2S] cluster binding domain involved in electron transfer; nitrite reductase (NAD(P)H) small subunit 3229565 nirD 9796177 nirD Arthrobacter arilaitensis Re117 nitrite reductase (NAD(P)H) small subunit YP_003918055.1 3229188 R 861360 CDS YP_003918056.1 308178650 9794142 3229924..3232539 1 NC_014550.1 the assimilatory nitrite reductase catalyses the following reaction: ammonium hydroxide + 3 NAD(P)(+) + H(2)O <=> nitrite + 3 NAD(P)H; nitrite reductase (NAD(P)H) large subunit 3232539 nirB 9794142 nirB Arthrobacter arilaitensis Re117 nitrite reductase (NAD(P)H) large subunit YP_003918056.1 3229924 D 861360 CDS YP_003918057.1 308178651 9794141 complement(3232562..3233557) 1 NC_014550.1 identified by match to PF00248 family: Aldo/keto reductase family. This family includes a number of K+ ion channel beta chain regulatory domains - these are reported to have oxidoreductase activity; aldo-keto reductase family protein 3233557 9794141 AARI_28920 Arthrobacter arilaitensis Re117 aldo-keto reductase family protein YP_003918057.1 3232562 R 861360 CDS YP_003918058.1 308178652 9796178 3233685..3234572 1 NC_014550.1 identified by match to protein family PF01145. The band 7 protein is an integral membrane protein which is thought to regulate cation conductance. A variety of proteins belong to this family; band 7 family protein 3234572 9796178 AARI_28930 Arthrobacter arilaitensis Re117 band 7 family protein YP_003918058.1 3233685 D 861360 CDS YP_003918059.1 308178653 9796181 complement(3236280..3238601) 1 NC_014550.1 formate dehydrogenase catalyses the formation of CO(2) and NADH from formate and NAD(+); formate dehydrogenase 3238601 fdhF 9796181 fdhF Arthrobacter arilaitensis Re117 formate dehydrogenase YP_003918059.1 3236280 R 861360 CDS YP_003918060.1 308178654 9793847 complement(3238659..3239489) 1 NC_014550.1 necessary for nitrate inducible formate dehydrogenase activity; formate dehydrogenase family accessory protein FdhD 3239489 fdhD 9793847 fdhD Arthrobacter arilaitensis Re117 formate dehydrogenase family accessory protein FdhD YP_003918060.1 3238659 R 861360 CDS YP_003918061.1 308178655 9793846 3239585..3240424 1 NC_014550.1 identified by match to PF00583: acetyltransferase (GNAT) family; GNAT family acetyltransferase 3240424 9793846 AARI_28980 Arthrobacter arilaitensis Re117 GNAT family acetyltransferase YP_003918061.1 3239585 D 861360 CDS YP_003918062.1 308178656 9796182 complement(3240402..3241172) 1 NC_014550.1 identified by match to PF00903: glyoxalase/bleomycin resistance protein/dioxygenase superfamily; glyoxalase family protein 3241172 9796182 AARI_28990 Arthrobacter arilaitensis Re117 glyoxalase family protein YP_003918062.1 3240402 R 861360 CDS YP_003918063.1 308178657 9796183 3241364..3242923 1 NC_014550.1 activates fatty acids by binding to coenzyme A. Possibly involved in the synthesis of cellular lipids or their degradation via beta-oxidation; fatty-acid--CoA ligase 3242923 9796183 AARI_29000 Arthrobacter arilaitensis Re117 fatty-acid--CoA ligase YP_003918063.1 3241364 D 861360 CDS YP_003918064.1 308178658 9796184 complement(3242930..3243724) 1 NC_014550.1 match to protein family PF00378. This family contains a diverse set of enzymes including: Enoyl-CoA hydratase, Napthoate synthase, Carnitate racemase, 3- hydoxybutyryl-CoA dehydratase, Dodecanoyl-CoA delta- isomerase; enoyl-CoA hydratase/isomerase family protein 3243724 9796184 AARI_29010 Arthrobacter arilaitensis Re117 enoyl-CoA hydratase/isomerase family protein YP_003918064.1 3242930 R 861360 CDS YP_003918065.1 308178659 9796186 3244230..3244748 1 NC_014550.1 4 transmembrane helices predicted by TMHMM2.0; hypothetical protein 3244748 9796186 AARI_29030 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918065.1 3244230 D 861360 CDS YP_003918066.1 308178660 9796187 complement(3244745..3245350) 1 NC_014550.1 response regulators are key elements in two- component signal transduction systems, which enable bacteria to sense, respond, and adapt to a wide range of environments, stressors, and growth conditions; two-component system response regulator 3245350 9796187 AARI_29040 Arthrobacter arilaitensis Re117 two-component system response regulator YP_003918066.1 3244745 R 861360 CDS YP_003918067.1 308178661 9796188 complement(3245347..3246501) 1 NC_014550.1 protein-histidine kinases are key elements in two- component signal transduction systems, which enable bacteria to sense, respond, and adapt to a wide range of environments, stressors, and growth conditions. 5 transmembrane helices predicted by TMHMM2.0; signal transduction histidine kinase 3246501 9796188 AARI_29050 Arthrobacter arilaitensis Re117 signal transduction histidine kinase YP_003918067.1 3245347 R 861360 CDS YP_003918068.1 308178662 9796189 complement(3246498..3247253) 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, drug exporter-1 (DrugE1) family (TC 3.A.1.105.z). ABCISSE: ABC transporter, permease (IM), DRA-family (Drug and Antibiotic resistance), DRR-subfamily (Polyketide drug resistance). The typical organization of DRR systems consists of 1 ABC transporter (ABC) and 1 or 2 permeases (IM). Possible function in drug efflux; ABC drug resistance transporter, inner membrane subunit 3247253 9796189 AARI_29060 Arthrobacter arilaitensis Re117 ABC drug resistance transporter, inner membrane subunit YP_003918068.1 3246498 R 861360 CDS YP_003918069.1 308178663 9796190 complement(3247250..3248167) 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, drug exporter-1 (DrugE1) family (TC 3.A.1.105.z). ABCISSE: ABC transporter, ATP-binding protein (ABC), DRA-family (Drug and Antibiotic resistance), DRR-subfamily (Polyketide drug resistance). The typical organization of DRR systems consists of 1 ABC transporter (ABC) and 1 or 2 permeases (IM). Possible function in drug efflux; ABC drug resistance transporter, ATP-binding subunit 3248167 9796190 AARI_29070 Arthrobacter arilaitensis Re117 ABC drug resistance transporter, ATP-binding subunit YP_003918069.1 3247250 R 861360 CDS YP_003918070.1 308178664 9796272 3248485..3249189 1 NC_014550.1 5 transmembrane helices predicted by TMHMM2.0; hypothetical protein 3249189 9796272 AARI_29080 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918070.1 3248485 D 861360 CDS YP_003918071.1 308178665 9796273 complement(3249193..3249549) 1 NC_014550.1 hypothetical protein 3249549 9796273 AARI_29090 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918071.1 3249193 R 861360 CDS YP_003918072.1 308178666 9796274 3249665..3250522 1 NC_014550.1 match to PF00196: Bacterial regulatory proteins, luxR family; DNA binding domain-containing protein 3250522 9796274 AARI_29100 Arthrobacter arilaitensis Re117 DNA binding domain-containing protein YP_003918072.1 3249665 D 861360 CDS YP_003918073.1 308178667 9796275 3250902..3252098 1 NC_014550.1 transposase of ISAar2, IS110 family 3252098 9796275 AARI_35630 Arthrobacter arilaitensis Re117 transposase of ISAar2, IS110 family YP_003918073.1 3250902 D 861360 CDS YP_003918074.1 308178668 9793504 3252492..3253040 1 NC_014550.1 signal peptide predicted by SignalP 3.0 HMM (probability: 0.999) with cleavage site probability 0.712 between position 26 and 27; hypothetical protein 3253040 9793504 AARI_29110 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918074.1 3252492 D 861360 CDS YP_003918075.1 308178669 9796276 3253049..3253612 1 NC_014550.1 2 transmembrane helices predicted by TMHMM2.0; hypothetical protein 3253612 9796276 AARI_29120 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918075.1 3253049 D 861360 CDS YP_003918076.1 308178670 9796277 3253609..3254241 1 NC_014550.1 match to protein domain TIGR00746: LPXTG-motif cell wall anchor. Surface proteins from Gram-positive cocci are covalently linked to the bacterial cell wall by sortase, a membrane-anchored transpeptidase that cleaves proteins between the threonine and the glycine of a conserved LPxTG motif, with the formation of a thioester between the conserved cysteine of sortase and the threonine carboxyl group. The newly liberated C-terminus of the threonine is transferred via an amide bond exchange to the amino group of the pentaglycine wall crossbridge, thereby tethering the C-terminus end of the surface protein to the bacterial peptidoglycan.The proteins that contain the conserved hexapeptide and hydrophobic anchor are diverse: they include M proteins, IgA and IgG binding proteins, fibronectin-binding proteins, wall-associated proteins, trypsin-resistant surface T protein, protein H precursor, etc. Signal peptide predicted by SignalP 3.0 HMM (probability: 1.000) with cleavage site probability 0.628 between position 24 and 25; cell surface protein 3254241 9796277 AARI_29130 Arthrobacter arilaitensis Re117 cell surface protein YP_003918076.1 3253609 D 861360 CDS YP_003918077.1 308178671 9796278 3254348..3254821 1 NC_014550.1 hypothetical protein 3254821 9796278 AARI_29140 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918077.1 3254348 D 861360 CDS YP_003918078.1 308178672 9796279 3254821..3255381 1 NC_014550.1 2 transmembrane helices predicted by TMHMM2.0; hypothetical protein 3255381 9796279 AARI_29150 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918078.1 3254821 D 861360 CDS YP_003918079.1 308178673 9796280 3255704..3256216 1 NC_014550.1 signal peptide predicted by SignalP 3.0 HMM (probability: 1.000) with cleavage site probability 0.487 between position 34 and 35; hypothetical protein 3256216 9796280 AARI_29160 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918079.1 3255704 D 861360 CDS YP_003918080.1 308178674 9796281 3256635..3257942 1 NC_014550.1 transposase of ISAar20, ISL3 family 3257942 9796281 AARI_35640 Arthrobacter arilaitensis Re117 transposase of ISAar20, ISL3 family YP_003918080.1 3256635 D 861360 CDS YP_003918081.1 308178675 9793505 complement(3258008..3259204) 1 NC_014550.1 catalyses the following reaction: L-aspartate + 2- oxoglutarate <=> oxaloacetate + L-glutamate; aspartate transaminase 3259204 9793505 AARI_29170 Arthrobacter arilaitensis Re117 aspartate transaminase YP_003918081.1 3258008 R 861360 CDS YP_003918082.1 308178676 9796282 3259441..3261336 1 NC_014550.1 identified by match to PF00149. The metallo- phosphoesterase motif is found in a large number of proteins invoved in phosphorylation. These include Ser/Thr phosphatases, DNA polymerase, exonucleases, and other phosphatases; phosphoesterase 3261336 9796282 AARI_29180 Arthrobacter arilaitensis Re117 phosphoesterase YP_003918082.1 3259441 D 861360 CDS YP_003918083.1 308178677 9796283 complement(3261379..3262503) 1 NC_014550.1 10 transmembrane helices predicted by TMHMM2.0; hypothetical protein 3262503 9796283 AARI_29190 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918083.1 3261379 R 861360 CDS YP_003918084.1 308178678 9796289 3264844..3266289 1 NC_014550.1 transposase of ISAar22, IS481 family 3266289 9796289 AARI_35650 Arthrobacter arilaitensis Re117 transposase of ISAar22, IS481 family YP_003918084.1 3264844 D 861360 CDS YP_003918085.1 308178679 9793506 3266435..3267112 1 NC_014550.1 identified by match to PF00702. This family includes L-2-haloacid dehalogenase, epoxide hydrolases and phosphatases; haloacid dehalogenase 3267112 9793506 AARI_29250 Arthrobacter arilaitensis Re117 haloacid dehalogenase YP_003918085.1 3266435 D 861360 CDS YP_003918086.1 308178680 9796290 3267202..3267789 1 NC_014550.1 identified by match to PF00702. This family includes L-2-haloacid dehalogenase, epoxide hydrolases and phosphatases; haloacid dehalogenase 3267789 9796290 AARI_29260 Arthrobacter arilaitensis Re117 haloacid dehalogenase YP_003918086.1 3267202 D 861360 CDS YP_003918087.1 308178681 9796291 complement(3268150..3268818) 1 NC_014550.1 match to PTHR11638: ATP-dependent CLP protease; hypothetical protein 3268818 9796291 AARI_29270 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918087.1 3268150 R 861360 CDS YP_003918088.1 308178682 9796292 complement(3269005..3269751) 1 NC_014550.1 hypothetical protein 3269751 9796292 AARI_29280 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918088.1 3269005 R 861360 CDS YP_003918089.1 308178683 9796293 3269934..3270329 1 NC_014550.1 signal peptide predicted by SignalP 3.0 HMM (probability: 0.999) with cleavage site probability 0.726 between position 24 and 25. 2 transmembrane helices predicted by TMHMM2.0 after the signal peptide; hypothetical protein 3270329 9796293 AARI_29290 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918089.1 3269934 D 861360 CDS YP_003918090.1 308178684 9796294 complement(3270377..3270919) 1 NC_014550.1 identified by match to PF00583: acetyltransferase (GNAT) family; GNAT family acetyltransferase 3270919 9796294 AARI_29300 Arthrobacter arilaitensis Re117 GNAT family acetyltransferase YP_003918090.1 3270377 R 861360 CDS YP_003918091.1 308178685 9796295 3271155..3271439 1 NC_014550.1 transposase of ISAar43, IS3 family, IS407 group, orfA 3271439 9796295 AARI_35660 Arthrobacter arilaitensis Re117 transposase of ISAar43, IS3 family, IS407 group, orfA YP_003918091.1 3271155 D 861360 CDS YP_003918092.1 308178686 9793507 3271502..3272305 1 NC_014550.1 transposase of ISAar43, IS3 family, IS407 group, orfB 3272305 9793507 AARI_35670 Arthrobacter arilaitensis Re117 transposase of ISAar43, IS3 family, IS407 group, orfB YP_003918092.1 3271502 D 861360 CDS YP_003918093.1 308178687 9793508 complement(3272641..3273012) 1 NC_014550.1 hypothetical protein 3273012 9793508 AARI_29310 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918093.1 3272641 R 861360 CDS YP_003918094.1 308178688 9796296 3273044..3273214 1 NC_014550.1 1 transmembrane helice predicted by TMHMM2.0; hypothetical protein 3273214 9796296 AARI_29320 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918094.1 3273044 D 861360 CDS YP_003918095.1 308178689 9796297 3273605..3274549 1 NC_014550.1 lysophospholipase catalyses the release of fatty acids from lysophospholipids; lysophospholipase 3274549 9796297 AARI_29330 Arthrobacter arilaitensis Re117 lysophospholipase YP_003918095.1 3273605 D 861360 CDS YP_003918096.1 308178690 9793509 complement(3275149..3276156) 1 NC_014550.1 type I restriction endonucleases are components of prokaryotic DNA restriction-modification mechanisms that protects the organism against invading foreign DNA. They have three different subunits: subunits - M (modification), S (specificity) and R (restriction) - that form multifunctional enzymes with restriction (EC:3.1.21.3), methylase (EC:2.1.1.72) and ATPase activities. The S subunit is required for both restriction and modification and is responsible for recognition of the DNA sequence specific for the system. The M subunit is necessary for modification, and the R subunit is required for restriction. They recognize asymmetric DNA sequences split into two domains of specific sequence, one 3-4 bp long and another 4-5 bp long, separated by a nonspecific spacer 6-8 bp in length. Cleavage occurs a considerable distance from the recognition sites, rarely less than 400 bp away and up to 7000 bp away. Adenosyl residues are methylated, one on each strand of the recognition sequence; type I restriction-modification system specificity subunit 3276156 hsdS 9793509 hsdS Arthrobacter arilaitensis Re117 type I restriction-modification system specificity subunit YP_003918096.1 3275149 R 861360 CDS YP_003918097.1 308178691 9793984 complement(3276153..3278018) 1 NC_014550.1 type I restriction endonucleases are components of prokaryotic DNA restriction-modification mechanisms that protects the organism against invading foreign DNA. They have three different subunits: subunits - M (modification), S (specificity) and R (restriction) - that form multifunctional enzymes with restriction (EC:3.1.21.3), methylase (EC:2.1.1.72) and ATPase activities. The S subunit is required for both restriction and modification and is responsible for recognition of the DNA sequence specific for the system. The M subunit is necessary for modification, and the R subunit is required for restriction. They recognize asymmetric DNA sequences split into two domains of specific sequence, one 3-4 bp long and another 4-5 bp long, separated by a nonspecific spacer 6-8 bp in length. Cleavage occurs a considerable distance from the recognition sites, rarely less than 400 bp away and up to 7000 bp away. Adenosyl residues are methylated, one on each strand of the recognition sequence; type I restriction-modification system modification subunit 3278018 hsdM 9793984 hsdM Arthrobacter arilaitensis Re117 type I restriction-modification system modification subunit YP_003918097.1 3276153 R 861360 CDS YP_003918098.1 308178692 9793979 complement(3278077..3278331) 1 NC_014550.1 2 transmembrane helices predicted by TMHMM2.0; hypothetical protein 3278331 9793979 AARI_29360 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918098.1 3278077 R 861360 CDS YP_003918099.1 308178693 9796299 3278452..3279060 1 NC_014550.1 identified by match to PF07719. The tetratrico peptide repeat (TPR) is a structural motif present in a wide range of proteins. It mediates protein-protein interactions and the assembly of multiprotein complexes. TPR motifs have been identified in various different organisms, ranging from bacteria to humans. Proteins containing TPRs are involved in a variety of biological processes, such as cell cycle regulation, transcriptional control, mitochondrial and peroxisomal protein transport, neurogenesis and protein folding; tetratrico peptide repeat-containing protein 3279060 9796299 AARI_29370 Arthrobacter arilaitensis Re117 tetratrico peptide repeat-containing protein YP_003918099.1 3278452 D 861360 CDS YP_003918100.1 308178694 9796300 complement(3279695..3279997) 1 NC_014550.1 hypothetical protein 3279997 9796300 AARI_29380 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918100.1 3279695 R 861360 CDS YP_003918101.1 308178695 9796301 complement(3280298..3281575) 1 NC_014550.1 transposase of ISAar13, ISL3 family 3281575 9796301 AARI_35690 Arthrobacter arilaitensis Re117 transposase of ISAar13, ISL3 family YP_003918101.1 3280298 R 861360 CDS YP_003918102.1 308178696 9793510 complement(3281807..3283747) 1 NC_014550.1 TCDB: P-type ATPase (P-ATPase) superfamily (TC 3.A. 3.y.z). Involved in export of cations; cation-transporting ATPase 3283747 9793510 AARI_29390 Arthrobacter arilaitensis Re117 cation-transporting ATPase YP_003918102.1 3281807 R 861360 CDS YP_003918103.1 308178697 9796302 complement(3283744..3284112) 1 NC_014550.1 identified by match to PF01022: bacterial regulatory protein, ArsR family. ArsR-family transcriptional regulators include several proteins that appear to dissociate from DNA in the presence of metal ions; ArsR family transcriptional regulator 3284112 9796302 AARI_29400 Arthrobacter arilaitensis Re117 ArsR family transcriptional regulator YP_003918103.1 3283744 R 861360 CDS YP_003918104.1 308178698 9796303 complement(3284272..3285519) 1 NC_014550.1 transposase of ISAar13, ISL3 family 3285519 9796303 AARI_35700 Arthrobacter arilaitensis Re117 transposase of ISAar13, ISL3 family YP_003918104.1 3284272 R 861360 CDS YP_003918105.1 308178699 9793511 complement(3285685..3286314) 1 NC_014550.1 4 transmembrane helices predicted by TMHMM2.0; hypothetical protein 3286314 9793511 AARI_29410 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918105.1 3285685 R 861360 CDS YP_003918106.1 308178700 9796304 complement(3286311..3286649) 1 NC_014550.1 identified by match to protein family PF03551; PadR-like family transcriptional regulator 3286649 9796304 AARI_29420 Arthrobacter arilaitensis Re117 PadR-like family transcriptional regulator YP_003918106.1 3286311 R 861360 CDS YP_003918107.1 308178701 9793514 3287693..3289156 1 NC_014550.1 transposase of ISAar7, IS21 family, istA 3289156 istA 9793514 istA Arthrobacter arilaitensis Re117 transposase of ISAar7, IS21 family, istA YP_003918107.1 3287693 D 861360 CDS YP_003918108.1 308178702 9794017 3289153..3289884 1 NC_014550.1 helper of transposition of ISAar7, IS21 family, istB 3289884 istB 9794017 istB Arthrobacter arilaitensis Re117 helper of transposition of ISAar7, IS21 family, istB YP_003918108.1 3289153 D 861360 CDS YP_003918109.1 308178703 9794020 3289881..3290213 1 NC_014550.1 hypothetical protein 3290213 9794020 AARI_29430 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918109.1 3289881 D 861360 CDS YP_003918110.1 308178704 9796306 3290347..3291735 1 NC_014550.1 first part of the IS; transposase of ISAar6, IS256 family 3291735 9796306 AARI_35760 Arthrobacter arilaitensis Re117 transposase of ISAar6, IS256 family YP_003918110.1 3290347 D 861360 CDS YP_003918111.1 308178705 9793515 complement(3291770..3292840) 1 NC_014550.1 transposase of ISAar1, IS1595 family, ISSod11 group 3292840 9793515 AARI_35770 Arthrobacter arilaitensis Re117 transposase of ISAar1, IS1595 family, ISSod11 group YP_003918111.1 3291770 R 861360 CDS YP_003918112.1 308178706 9793516 3293277..3293519 1 NC_014550.1 hypothetical protein 3293519 9793516 AARI_29440 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918112.1 3293277 D 861360 CDS YP_003918113.1 308178707 9796307 3293946..3294248 1 NC_014550.1 hypothetical protein 3294248 9796307 AARI_29450 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918113.1 3293946 D 861360 CDS YP_003918114.1 308178708 9796308 complement(3294339..3295538) 1 NC_014550.1 transposase of ISAar5, IS256 family 3295538 9796308 AARI_35780 Arthrobacter arilaitensis Re117 transposase of ISAar5, IS256 family YP_003918114.1 3294339 R 861360 CDS YP_003918115.1 308178709 9793517 complement(3296469..3297776) 1 NC_014550.1 transposase of ISAar23, ISL3 family 3297776 9793517 AARI_35790 Arthrobacter arilaitensis Re117 transposase of ISAar23, ISL3 family YP_003918115.1 3296469 R 861360 CDS YP_003918116.1 308178710 9796309 3299408..3301168 1 NC_014550.1 identified by match to protein family PF02534. The TraG family are bacterial conjugation proteins. These proteins aid the transfer of DNA from the plasmid into the host bacterial chromosome although the exact mechanism of action is unknown; TraG family bacterial conjugation protein 3301168 9796309 AARI_29470 Arthrobacter arilaitensis Re117 TraG family bacterial conjugation protein YP_003918116.1 3299408 D 861360 CDS YP_003918117.1 308178711 9796310 3301165..3301782 1 NC_014550.1 hypothetical protein 3301782 9796310 AARI_29480 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918117.1 3301165 D 861360 CDS YP_003918118.1 308178712 9796311 complement(3301994..3302563) 1 NC_014550.1 hypothetical protein 3302563 9796311 AARI_29490 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918118.1 3301994 R 861360 CDS YP_003918119.1 308178713 9796312 complement(3302560..3303141) 1 NC_014550.1 identified by match to SM00530: Helix-turn-helix XRE-family like proteins. This is a large family of DNA binding helix-turn helix proteins that include a bacterial plasmid copy control protein, bacterial methylases, various bacteriophage transcription control proteins and a vegetative specific protein from Dictyostelium discoideum (Slime mould); DNA binding domain-containing protein 3303141 9796312 AARI_29500 Arthrobacter arilaitensis Re117 DNA binding domain-containing protein YP_003918119.1 3302560 R 861360 CDS YP_003918120.1 308178714 9796314 3304202..3304990 1 NC_014550.1 hypothetical protein 3304990 9796314 AARI_29520 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918120.1 3304202 D 861360 CDS YP_003918121.1 308178715 9796315 3305009..3305251 1 NC_014550.1 2 transmembrane helices predicted by TMHMM2.0; hypothetical protein 3305251 9796315 AARI_29530 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918121.1 3305009 D 861360 CDS YP_003918122.1 308178716 9796316 3305456..3306763 1 NC_014550.1 transposase of ISAar23, ISL3 family 3306763 9796316 AARI_35800 Arthrobacter arilaitensis Re117 transposase of ISAar23, ISL3 family YP_003918122.1 3305456 D 861360 CDS YP_003918123.1 308178717 9796317 3309073..3310641 1 NC_014550.1 serine recombinases demonstrate functional versatility and include resolvases, invertases, integrases, and transposases. This protein may be a resolvase (match to PF07508 and PF00239); site-specific recombinase 3310641 9796317 AARI_29550 Arthrobacter arilaitensis Re117 site-specific recombinase YP_003918123.1 3309073 D 861360 CDS YP_003918124.1 308178718 9796318 complement(3311857..3312117) 1 NC_014550.1 2 transmembrane helices predicted by TMHMM2.0; hypothetical protein 3312117 9796318 AARI_29560 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918124.1 3311857 R 861360 CDS YP_003918125.1 308178719 9796319 3312431..3313129 1 NC_014550.1 signal peptide predicted by SignalP 3.0 HMM (probability: 0.992) with cleavage site probability 0.849 between position 33 and 34; hypothetical protein 3313129 9796319 AARI_29570 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918125.1 3312431 D 861360 CDS YP_003918126.1 308178720 9796320 complement(3313143..3313517) 1 NC_014550.1 2 transmembrane helices predicted by TMHMM2.0; hypothetical protein 3313517 9796320 AARI_29580 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918126.1 3313143 R 861360 CDS YP_003918127.1 308178721 9796321 complement(3313846..3314868) 1 NC_014550.1 transposase of ISAar25, IS3 family, IS3 group, orfB 3314868 9796321 AARI_35810 Arthrobacter arilaitensis Re117 transposase of ISAar25, IS3 family, IS3 group, orfB YP_003918127.1 3313846 R 861360 CDS YP_003918128.1 308178722 9793520 complement(3314763..3315056) 1 NC_014550.1 transposase of ISAar25, IS3 family, IS3 group, orfA 3315056 9793520 AARI_35820 Arthrobacter arilaitensis Re117 transposase of ISAar25, IS3 family, IS3 group, orfA YP_003918128.1 3314763 R 861360 CDS YP_003918129.1 308178723 9796323 complement(3318675..3319235) 1 NC_014550.1 hypothetical protein 3319235 9796323 AARI_29610 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918129.1 3318675 R 861360 CDS YP_003918130.1 308178724 9796325 3322632..3323066 1 NC_014550.1 hypothetical protein 3323066 9796325 AARI_29630 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918130.1 3322632 D 861360 CDS YP_003918131.1 308178725 9796326 complement(3323347..3323769) 1 NC_014550.1 hypothetical protein 3323769 9796326 AARI_29640 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918131.1 3323347 R 861360 CDS YP_003918132.1 308178726 9796327 3325418..3326329 1 NC_014550.1 hypothetical protein 3326329 9796327 AARI_29650 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918132.1 3325418 D 861360 CDS YP_003918133.1 308178727 9796328 3326527..3326781 1 NC_014550.1 hypothetical protein 3326781 9796328 AARI_29660 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918133.1 3326527 D 861360 CDS YP_003918134.1 308178728 9796329 3327323..3328447 1 NC_014550.1 signal peptide predicted by SignalP 3.0 HMM (probability: 0.807) with cleavage site probability 0.454 between position 19 and 20; hypothetical protein 3328447 9796329 AARI_29670 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918134.1 3327323 D 861360 CDS YP_003918135.1 308178729 9796330 3328481..3328900 1 NC_014550.1 hypothetical protein 3328900 9796330 AARI_29680 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918135.1 3328481 D 861360 CDS YP_003918136.1 308178730 9796332 3329677..3329829 1 NC_014550.1 1 transmembrane helice predicted by TMHMM2.0; hypothetical protein 3329829 9796332 AARI_29700 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918136.1 3329677 D 861360 CDS YP_003918137.1 308178731 9793523 3331942..3332673 1 NC_014550.1 helper of transposition of ISAar7, IS21 family, istB 3332673 istB 9793523 istB Arthrobacter arilaitensis Re117 helper of transposition of ISAar7, IS21 family, istB YP_003918137.1 3331942 D 861360 CDS YP_003918138.1 308178732 9794021 3332670..3333002 1 NC_014550.1 hypothetical protein 3333002 9794021 AARI_29710 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918138.1 3332670 D 861360 CDS YP_003918139.1 308178733 9796334 3333912..3334307 1 NC_014550.1 hypothetical protein 3334307 9796334 AARI_29720 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918139.1 3333912 D 861360 CDS YP_003918140.1 308178734 9796336 3335117..3336238 1 NC_014550.1 hypothetical protein 3336238 9796336 AARI_29740 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918140.1 3335117 D 861360 CDS YP_003918141.1 308178735 9796337 3336245..3336601 1 NC_014550.1 hypothetical protein 3336601 9796337 AARI_29750 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918141.1 3336245 D 861360 CDS YP_003918142.1 308178736 9796338 3336842..3337189 1 NC_014550.1 hypothetical protein 3337189 9796338 AARI_29760 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918142.1 3336842 D 861360 CDS YP_003918143.1 308178737 9796339 3337473..3338141 1 NC_014550.1 match to PF00239 and PF02796. Possibly involved in site-specific recombination of DNA; resolvase 3338141 9796339 AARI_29770 Arthrobacter arilaitensis Re117 resolvase YP_003918143.1 3337473 D 861360 CDS YP_003918144.1 308178738 9796340 3338406..3338693 1 NC_014550.1 hypothetical protein 3338693 9796340 AARI_29780 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918144.1 3338406 D 861360 CDS YP_003918145.1 308178739 9796341 complement(3339036..3339536) 1 NC_014550.1 3 transmembrane helices predicted by TMHMM2.0; hypothetical protein 3339536 9796341 AARI_29790 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918145.1 3339036 R 861360 CDS YP_003918146.1 308178740 9796342 complement(3339816..3340859) 1 NC_014550.1 hypothetical protein 3340859 9796342 AARI_29800 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918146.1 3339816 R 861360 CDS YP_003918147.1 308178741 9796343 3341268..3341765 1 NC_014550.1 signal peptide predicted by SignalP 3.0 HMM (probability: 1.000) with cleavage site probability 0.854 between position 36 and 37; hypothetical protein 3341765 9796343 AARI_29810 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918147.1 3341268 D 861360 CDS YP_003918148.1 308178742 9796344 3342128..3342421 1 NC_014550.1 transposase of ISAar25, IS3 family, IS3 group, orfA 3342421 9796344 AARI_35860 Arthrobacter arilaitensis Re117 transposase of ISAar25, IS3 family, IS3 group, orfA YP_003918148.1 3342128 D 861360 CDS YP_003918149.1 308178743 9793525 complement(3342787..3343149) 1 NC_014550.1 signal peptide predicted by SignalP 3.0 HMM (probability: 0.999) with cleavage site probability 0.750 between position 34 and 35; hypothetical protein 3343149 9793525 AARI_29820 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918149.1 3342787 R 861360 CDS YP_003918150.1 308178744 9793527 3343944..3344207 1 NC_014550.1 hypothetical protein 3344207 9793527 AARI_29830 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918150.1 3343944 D 861360 CDS YP_003918151.1 308178745 9793529 complement(3346048..3347190) 1 NC_014550.1 7 transmembrane helices predicted by TMHMM2.0; hypothetical protein 3347190 9793529 AARI_29840 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918151.1 3346048 R 861360 CDS YP_003918152.1 308178746 9796347 complement(3347456..3348205) 1 NC_014550.1 transposase of ISAar3, IS3 family, IS407 group, orfB 3348205 9796347 AARI_35920 Arthrobacter arilaitensis Re117 transposase of ISAar3, IS3 family, IS407 group, orfB YP_003918152.1 3347456 R 861360 CDS YP_003918153.1 308178747 9793530 complement(3348325..3348546) 1 NC_014550.1 transposase of ISAar3, IS3 family, IS407 group, orfA 3348546 9793530 AARI_35930 Arthrobacter arilaitensis Re117 transposase of ISAar3, IS3 family, IS407 group, orfA YP_003918153.1 3348325 R 861360 CDS YP_003918154.1 308178748 9793531 3349156..3349557 1 NC_014550.1 hypothetical protein 3349557 9793531 AARI_29850 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918154.1 3349156 D 861360 CDS YP_003918155.1 308178749 9796348 3350030..3350761 1 NC_014550.1 transposase of ISAar38, IS5 family, IS427 group 3350761 9796348 AARI_35940 Arthrobacter arilaitensis Re117 transposase of ISAar38, IS5 family, IS427 group YP_003918155.1 3350030 D 861360 CDS YP_003918156.1 308178750 9793532 complement(3350848..3351321) 1 NC_014550.1 hypothetical protein 3351321 9793532 AARI_29860 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918156.1 3350848 R 861360 CDS YP_003918157.1 308178751 9796349 3351737..3352126 1 NC_014550.1 hypothetical protein 3352126 9796349 AARI_29870 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918157.1 3351737 D 861360 CDS YP_003918158.1 308178752 9796350 complement(3352383..3352976) 1 NC_014550.1 match to PF00239 and PF02796. Possibly involved in site-specific recombination of DNA; resolvase 3352976 9796350 AARI_29880 Arthrobacter arilaitensis Re117 resolvase YP_003918158.1 3352383 R 861360 CDS YP_003918159.1 308178753 9796351 complement(3353160..3354467) 1 NC_014550.1 transposase of ISAar19, ISL3 family 3354467 9796351 AARI_35950 Arthrobacter arilaitensis Re117 transposase of ISAar19, ISL3 family YP_003918159.1 3353160 R 861360 CDS YP_003918160.1 308178754 9793533 complement(3354627..3355568) 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, Manganese/Zinc/Iron Chelate Uptake Transporter (MZT) Family (TC 3.A.1.15.z). ABCISSE: ABC transporter, binding protein (BP), MET-family. This family is comprised of systems involved in the uptake of various metallic cations such as iron, manganese and zinc; iron/manganese/zinc ABC transporter substrate-binding protein 3355568 9793533 AARI_29890 Arthrobacter arilaitensis Re117 iron/manganese/zinc ABC transporter substrate-binding protein YP_003918160.1 3354627 R 861360 CDS YP_003918161.1 308178755 9796352 complement(3355607..3355876) 1 NC_014550.1 hypothetical protein 3355876 9796352 AARI_29900 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918161.1 3355607 R 861360 CDS YP_003918162.1 308178756 9796434 3356392..3357381 1 NC_014550.1 identified by match to protein family PF0775: Abi- like protein. This family, found in various bacterial species, contains sequences that are similar to the Abi group of proteins, which are involved in bacteriophage resistance mediated by abortive infection in Lactococcus species. The proteins are thought to have helix-turn-helix motifs, found in many DNA-binding proteins, allowing them to perform their function; abortive infection bacteriophage resistance protein 3357381 9796434 AARI_29910 Arthrobacter arilaitensis Re117 abortive infection bacteriophage resistance protein YP_003918162.1 3356392 D 861360 CDS YP_003918163.1 308178757 9796435 complement(3358029..3358604) 1 NC_014550.1 identified by match to PF03358. FMN reductase reductase catalyses the following reaction: NAD(P)H + FMN = NAD(P)(+) + FMNH(2); FMN reductase 3358604 9796435 AARI_29920 Arthrobacter arilaitensis Re117 FMN reductase YP_003918163.1 3358029 R 861360 CDS YP_003918164.1 308178758 9796436 complement(3358652..3359677) 1 NC_014550.1 ribonucleotide reductase catalyzes the reductive synthesis of deoxyribonucleotides from their corresponding ribonucleotides. It provides the precursors necessary for DNA synthesis. It is an oligomeric enzyme composed of a large subunit (700 to 1000 residues) and a small subunit (300 to 400 residues); ribonucleoside-diphosphate reductase subunit beta 3359677 nrdF2 9796436 nrdF2 Arthrobacter arilaitensis Re117 ribonucleoside-diphosphate reductase subunit beta YP_003918164.1 3358652 R 861360 CDS YP_003918165.1 308178759 9794147 complement(3359711..3361876) 1 NC_014550.1 catalyzes the reductive synthesis of deoxyribonucleotides from their corresponding ribonucleotides. It provides the precursors necessary for DNA synthesis. It is an oligomeric enzyme composed of a large subunit (700 to 1000 residues) and a small subunit (300 to 400 residues); ribonucleoside-diphosphate reductase subunit alpha 3361876 nrdE2 9794147 nrdE2 Arthrobacter arilaitensis Re117 ribonucleoside-diphosphate reductase subunit alpha YP_003918165.1 3359711 R 861360 CDS YP_003918166.1 308178760 9794145 complement(3361873..3362361) 1 NC_014550.1 identified by match to PF03358. FMN reductase reductase catalyses the following reaction: NAD(P)H + FMN = NAD(P)(+) + FMNH(2); FMN reductase 3362361 9794145 AARI_29950 Arthrobacter arilaitensis Re117 FMN reductase YP_003918166.1 3361873 R 861360 CDS YP_003918167.1 308178761 9796437 3362800..3363441 1 NC_014550.1 hypothetical protein 3363441 9796437 AARI_29960 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918167.1 3362800 D 861360 CDS YP_003918168.1 308178762 9796438 complement(3363639..3364052) 1 NC_014550.1 hypothetical protein 3364052 9796438 AARI_29970 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918168.1 3363639 R 861360 CDS YP_003918169.1 308178763 9796439 3364166..3364558 1 NC_014550.1 identified by match to protein family PF05713: bacterial mobilisation protein (MobC). This family consists of several bacterial MobC-like, mobilisation proteins. MobC proteins belong to the group of relaxases. Together with MobA and MobB they bind to a single cis- active site of a mobilising plasmid, the origin of transfer (oriT) region; mobilisation protein 3364558 9796439 AARI_29980 Arthrobacter arilaitensis Re117 mobilisation protein YP_003918169.1 3364166 D 861360 CDS YP_003918170.1 308178764 9796440 3364555..3366057 1 NC_014550.1 identified by match to protein family PF03432: Relaxase/Mobilisation nuclease domain. Relaxases/mobilisation proteins are required for the horizontal transfer of genetic information contained on plasmids that occurs during bacterial conjugation; mobilisation protein 3366057 9796440 AARI_29990 Arthrobacter arilaitensis Re117 mobilisation protein YP_003918170.1 3364555 D 861360 CDS YP_003918171.1 308178765 9796441 3366084..3366935 1 NC_014550.1 hypothetical protein 3366935 9796441 AARI_30000 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918171.1 3366084 D 861360 CDS YP_003918172.1 308178766 9796442 3366932..3367378 1 NC_014550.1 hypothetical protein 3367378 9796442 AARI_30010 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918172.1 3366932 D 861360 CDS YP_003918173.1 308178767 9796443 3367467..3367661 1 NC_014550.1 1 transmembrane helice predicted by TMHMM2.0; hypothetical protein 3367661 9796443 AARI_30020 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918173.1 3367467 D 861360 CDS YP_003918174.1 308178768 9796444 complement(3367857..3368285) 1 NC_014550.1 hypothetical protein 3368285 9796444 AARI_30030 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918174.1 3367857 R 861360 CDS YP_003918175.1 308178769 9796447 complement(3376113..3377834) 1 NC_014550.1 identified by match to protein family PF02534. The TraG family are bacterial conjugation proteins. These proteins aid the transfer of DNA from the plasmid into the host bacterial chromosome; TraG family bacterial conjugation protein 3377834 9796447 AARI_30060 Arthrobacter arilaitensis Re117 TraG family bacterial conjugation protein YP_003918175.1 3376113 R 861360 CDS YP_003918176.1 308178770 9796448 complement(3377834..3379447) 1 NC_014550.1 hypothetical protein 3379447 9796448 AARI_30070 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918176.1 3377834 R 861360 CDS YP_003918177.1 308178771 9796449 complement(3379447..3380958) 1 NC_014550.1 2 transmembrane helices predicted by TMHMM2.0; hypothetical protein 3380958 9796449 AARI_30080 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918177.1 3379447 R 861360 CDS YP_003918178.1 308178772 9796450 complement(3380961..3382574) 1 NC_014550.1 7 transmembrane helices predicted by TMHMM2.0; hypothetical protein 3382574 9796450 AARI_30090 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918178.1 3380961 R 861360 CDS YP_003918179.1 308178773 9796451 complement(3382584..3383303) 1 NC_014550.1 1 transmembrane helice predicted by TMHMM2.0; hypothetical protein 3383303 9796451 AARI_30100 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918179.1 3382584 R 861360 CDS YP_003918180.1 308178774 9796452 complement(3383341..3383622) 1 NC_014550.1 2 transmembrane helices predicted by TMHMM2.0; hypothetical protein 3383622 9796452 AARI_30110 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918180.1 3383341 R 861360 CDS YP_003918181.1 308178775 9796453 complement(3383635..3384252) 1 NC_014550.1 hypothetical protein 3384252 9796453 AARI_30120 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918181.1 3383635 R 861360 CDS YP_003918182.1 308178776 9796454 3384445..3384663 1 NC_014550.1 hypothetical protein 3384663 9796454 AARI_30130 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918182.1 3384445 D 861360 CDS YP_003918183.1 308178777 9796455 3384692..3386155 1 NC_014550.1 1 transmembrane helice predicted by TMHMM2.0; hypothetical protein 3386155 9796455 AARI_30140 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918183.1 3384692 D 861360 CDS YP_003918184.1 308178778 9796456 3386168..3387298 1 NC_014550.1 identified by match to protein family PF01551. Members of this family are zinc metallopeptidases with a range of specificities. Peptidase family M23 are also endopeptidases; M23 family peptidase 3387298 9796456 AARI_30150 Arthrobacter arilaitensis Re117 M23 family peptidase YP_003918184.1 3386168 D 861360 CDS YP_003918185.1 308178779 9796457 3387295..3387858 1 NC_014550.1 signal peptide predicted by SignalP 3.0 HMM (probability: 1.000) with cleavage site probability 0.338 between position 48 and 49; hypothetical protein 3387858 9796457 AARI_30160 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918185.1 3387295 D 861360 CDS YP_003918186.1 308178780 9796458 3387907..3389388 1 NC_014550.1 hypothetical protein 3389388 9796458 AARI_30170 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918186.1 3387907 D 861360 CDS YP_003918187.1 308178781 9796459 3389452..3390225 1 NC_014550.1 hypothetical protein 3390225 9796459 AARI_30180 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918187.1 3389452 D 861360 CDS YP_003918188.1 308178782 9796460 3390283..3391593 1 NC_014550.1 transposase of ISAar38, ISL3 family 3391593 9796460 AARI_35960 Arthrobacter arilaitensis Re117 transposase of ISAar38, ISL3 family YP_003918188.1 3390283 D 861360 CDS YP_003918189.1 308178783 9793534 complement(3391617..3392393) 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, iron chelate uptake transporter (FeCT) family (TC 3.A.1.14.z). ABCISSE: ABC transporter, ATP-binding protein (ABC), ISVH- family (iron siderophores, vitamin B12 and hemin); iron-siderophore ABC transporter ATP-binding subunit 3392393 9793534 AARI_30190 Arthrobacter arilaitensis Re117 iron-siderophore ABC transporter ATP-binding subunit YP_003918189.1 3391617 R 861360 CDS YP_003918190.1 308178784 9796461 complement(3392390..3393454) 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, iron chelate uptake transporter (FeCT) family (TC 3.A.1.14.z). ABCISSE: ABC transporter, permease (IM), ISVH-family (iron siderophores, vitamin B12 and hemin); iron-siderophore ABC transporter inner membrane subunit 3393454 9796461 AARI_30200 Arthrobacter arilaitensis Re117 iron-siderophore ABC transporter inner membrane subunit YP_003918190.1 3392390 R 861360 CDS YP_003918191.1 308178785 9796462 complement(3393444..3394475) 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, iron chelate uptake transporter (FeCT) family (TC 3.A.1.14.z). ABCISSE: ABC transporter, binding protein (BP), ISVH- family (iron siderophores, vitamin B12 and hemin); iron-siderophore ABC transporter substrate-binding protein 3394475 9796462 AARI_30210 Arthrobacter arilaitensis Re117 iron-siderophore ABC transporter substrate-binding protein YP_003918191.1 3393444 R 861360 CDS YP_003918192.1 308178786 9796463 complement(3394490..3395332) 1 NC_014550.1 AraC family transcriptional regulator 3395332 9796463 AARI_30220 Arthrobacter arilaitensis Re117 AraC family transcriptional regulator YP_003918192.1 3394490 R 861360 CDS YP_003918193.1 308178787 9796464 3395521..3395820 1 NC_014550.1 transposase of ISAar24, IS3 family, IS3 group, orfA 3395820 9796464 AARI_35970 Arthrobacter arilaitensis Re117 transposase of ISAar24, IS3 family, IS3 group, orfA YP_003918193.1 3395521 D 861360 CDS YP_003918194.1 308178788 9793535 3395817..3396686 1 NC_014550.1 transposase of ISAar24, IS3 family, IS3 group, orfB 3396686 9793535 AARI_35980 Arthrobacter arilaitensis Re117 transposase of ISAar24, IS3 family, IS3 group, orfB YP_003918194.1 3395817 D 861360 CDS YP_003918195.1 308178789 9793537 3397191..3398492 1 NC_014550.1 transposase of ISAar42, ISL3 family 3398492 9793537 AARI_36000 Arthrobacter arilaitensis Re117 transposase of ISAar42, ISL3 family YP_003918195.1 3397191 D 861360 CDS YP_003918196.1 308178790 9793538 3398489..3398632 1 NC_014550.1 hypothetical protein 3398632 9793538 AARI_30230 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918196.1 3398489 D 861360 CDS YP_003918197.1 308178791 9793540 3400227..3400661 1 NC_014550.1 hypothetical protein 3400661 9793540 AARI_30240 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918197.1 3400227 D 861360 CDS YP_003918198.1 308178792 9796466 3400724..3400954 1 NC_014550.1 hypothetical protein 3400954 9796466 AARI_30250 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918198.1 3400724 D 861360 CDS YP_003918199.1 308178793 9796467 3401106..3402533 1 NC_014550.1 hypothetical protein 3402533 9796467 AARI_30260 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918199.1 3401106 D 861360 CDS YP_003918200.1 308178794 9796468 3402707..3402994 1 NC_014550.1 3 transmembrane helices predicted by TMHMM2.0; hypothetical protein 3402994 9796468 AARI_30270 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918200.1 3402707 D 861360 CDS YP_003918201.1 308178795 9796469 3403212..3403595 1 NC_014550.1 2 transmembrane helices predicted by TMHMM2.0; hypothetical protein 3403595 9796469 AARI_30280 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918201.1 3403212 D 861360 CDS YP_003918202.1 308178796 9796470 complement(3403643..3403933) 1 NC_014550.1 hypothetical protein 3403933 9796470 AARI_30290 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918202.1 3403643 R 861360 CDS YP_003918203.1 308178797 9796471 3404154..3404747 1 NC_014550.1 match to protein family PF01656. chromosome partitioning protein. Similar to uncharacterized plasmidic proteins; ParA family protein 3404747 9796471 AARI_30300 Arthrobacter arilaitensis Re117 ParA family protein YP_003918203.1 3404154 D 861360 CDS YP_003918204.1 308178798 9796472 3404744..3404980 1 NC_014550.1 hypothetical protein 3404980 9796472 AARI_30310 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918204.1 3404744 D 861360 CDS YP_003918205.1 308178799 9796473 3405441..3405827 1 NC_014550.1 hypothetical protein 3405827 9796473 AARI_30320 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918205.1 3405441 D 861360 CDS YP_003918206.1 308178800 9796474 3405881..3406048 1 NC_014550.1 hypothetical protein 3406048 9796474 AARI_30330 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918206.1 3405881 D 861360 CDS YP_003918207.1 308178801 9796475 3406065..3406289 1 NC_014550.1 electron transport system for the ribonucleotide reductase system nrdEF; glutaredoxin electron transport component NrdH 3406289 nrdH 9796475 nrdH Arthrobacter arilaitensis Re117 glutaredoxin electron transport component NrdH YP_003918207.1 3406065 D 861360 CDS YP_003918208.1 308178802 9794149 3406645..3407646 1 NC_014550.1 hypothetical protein 3407646 9794149 AARI_30350 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918208.1 3406645 D 861360 CDS YP_003918209.1 308178803 9796476 3407729..3408145 1 NC_014550.1 hypothetical protein 3408145 9796476 AARI_30360 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918209.1 3407729 D 861360 CDS YP_003918210.1 308178804 9796477 3408151..3408384 1 NC_014550.1 hypothetical protein 3408384 9796477 AARI_30370 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918210.1 3408151 D 861360 CDS YP_003918211.1 308178805 9796478 3408586..3408912 1 NC_014550.1 hypothetical protein 3408912 9796478 AARI_30380 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918211.1 3408586 D 861360 CDS YP_003918212.1 308178806 9796479 complement(3409072..3412347) 1 NC_014550.1 match to PR00507. Site-specific DNA- methyltransferases specifically methylate the amino group at the C-6 position of adenines in DNA. Such enzymes are found in the bacterial restriction-modification systems. Match to PS00092 pattern: N-6 Adenine-specific DNA methylases signature; site-specific DNA-methyltransferase (adenine specific) 3412347 9796479 AARI_30390 Arthrobacter arilaitensis Re117 site-specific DNA-methyltransferase (adenine specific) YP_003918212.1 3409072 R 861360 CDS YP_003918213.1 308178807 9796480 3412564..3412890 1 NC_014550.1 hypothetical protein 3412890 9796480 AARI_30400 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918213.1 3412564 D 861360 CDS YP_003918214.1 308178808 9796481 complement(3412975..3414378) 1 NC_014550.1 6 transmembrane helices predicted by TMHMM2.0; hypothetical protein 3414378 9796481 AARI_30410 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918214.1 3412975 R 861360 CDS YP_003918215.1 308178809 9796482 complement(3414461..3415615) 1 NC_014550.1 identified by match to protein family PF04261. This family of dye-decolourising peroxidases lack a typical heme-binding region; Dyp-type peroxidase family protein 3415615 9796482 AARI_30420 Arthrobacter arilaitensis Re117 Dyp-type peroxidase family protein YP_003918215.1 3414461 R 861360 CDS YP_003918216.1 308178810 9796483 complement(3415663..3416235) 1 NC_014550.1 signal peptide predicted by SignalP 3.0 HMM (probability: 1.000) with cleavage site probability 0.655 between position 38 and 39; hypothetical protein 3416235 9796483 AARI_30430 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918216.1 3415663 R 861360 CDS YP_003918217.1 308178811 9796484 complement(3416642..3417268) 1 NC_014550.1 signal peptide predicted by SignalP 3.0 HMM (probability: 0.997) with cleavage site probability 0.878 between position 33 and 34. 4 transmembrane helices predicted by TMHMM2.0 after the signal peptide; hypothetical protein 3417268 9796484 AARI_30440 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918217.1 3416642 R 861360 CDS YP_003918218.1 308178812 9796485 3417712..3417981 1 NC_014550.1 hypothetical protein 3417981 9796485 AARI_30450 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918218.1 3417712 D 861360 CDS YP_003918219.1 308178813 9796486 3418020..3418961 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, Manganese/Zinc/Iron Chelate Uptake Transporter (MZT) Family (TC 3.A.1.15.z). ABCISSE: ABC transporter, binding protein (BP), MET-family. This family is comprised of systems involved in the uptake of various metallic cations such as iron, manganese and zinc; iron/manganese/zinc ABC transporter substrate-binding protein 3418961 9796486 AARI_30460 Arthrobacter arilaitensis Re117 iron/manganese/zinc ABC transporter substrate-binding protein YP_003918219.1 3418020 D 861360 CDS YP_003918220.1 308178814 9796487 3418961..3419692 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, Manganese/Zinc/Iron Chelate Uptake Transporter (MZT) Family (TC 3.A.1.15.z). ABCISSE: ABC transporter, ATP- binding protein (ABC), MET-family. This family is comprised of systems involved in the uptake of various metallic cations such as iron, manganese and zinc; iron/manganese/zinc ABC transporter ATP-binding subunit 3419692 9796487 AARI_30470 Arthrobacter arilaitensis Re117 iron/manganese/zinc ABC transporter ATP-binding subunit YP_003918220.1 3418961 D 861360 CDS YP_003918221.1 308178815 9796488 3419695..3420582 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, Manganese/Zinc/Iron Chelate Uptake Transporter (MZT) Family (TC 3.A.1.15.z). ABCISSE: ABC transporter, permease (IM), MET-family. This family is comprised of systems involved in the uptake of various metallic cations such as iron, manganese and zinc; iron/manganese/zinc ABC transporter inner membrane subunit 3420582 9796488 AARI_30480 Arthrobacter arilaitensis Re117 iron/manganese/zinc ABC transporter inner membrane subunit YP_003918221.1 3419695 D 861360 CDS YP_003918222.1 308178816 9796490 3421748..3422305 1 NC_014550.1 hypothetical protein 3422305 9796490 AARI_30500 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918222.1 3421748 D 861360 CDS YP_003918223.1 308178817 9796491 3422293..3422754 1 NC_014550.1 hypothetical protein 3422754 9796491 AARI_30510 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918223.1 3422293 D 861360 CDS YP_003918224.1 308178818 9796492 3423063..3423647 1 NC_014550.1 match to PF00239. Possibly involved in site- specific recombination of DNA; resolvase 3423647 9796492 AARI_30520 Arthrobacter arilaitensis Re117 resolvase YP_003918224.1 3423063 D 861360 CDS YP_003918225.1 308178819 9793541 3425162..3425974 1 NC_014550.1 hypothetical protein 3425974 9793541 AARI_30530 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918225.1 3425162 D 861360 CDS YP_003918226.1 308178820 9796494 3426310..3426606 1 NC_014550.1 transposase of ISAar4, IS3 family, IS3 group, orfA 3426606 9796494 AARI_36040 Arthrobacter arilaitensis Re117 transposase of ISAar4, IS3 family, IS3 group, orfA YP_003918226.1 3426310 D 861360 CDS YP_003918227.1 308178821 9793542 3426669..3427496 1 NC_014550.1 transposase of ISAar4, IS3 family, IS3 group, orfB 3427496 9793542 AARI_36050 Arthrobacter arilaitensis Re117 transposase of ISAar4, IS3 family, IS3 group, orfB YP_003918227.1 3426669 D 861360 CDS YP_003918228.1 308178822 9793543 3427593..3428645 1 NC_014550.1 hypothetical protein 3428645 9793543 AARI_30540 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918228.1 3427593 D 861360 CDS YP_003918229.1 308178823 9796495 complement(3428771..3429103) 1 NC_014550.1 2 transmembrane helices predicted by TMHMM2.0; hypothetical protein 3429103 9796495 AARI_30550 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918229.1 3428771 R 861360 CDS YP_003918230.1 308178824 9796496 3429418..3430212 1 NC_014550.1 hypothetical protein 3430212 9796496 AARI_30560 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918230.1 3429418 D 861360 CDS YP_003918231.1 308178825 9796497 complement(3430285..3431331) 1 NC_014550.1 transposase of ISAar41, IS110 family 3431331 9796497 AARI_36060 Arthrobacter arilaitensis Re117 transposase of ISAar41, IS110 family YP_003918231.1 3430285 R 861360 CDS YP_003918232.1 308178826 9793544 3431673..3431999 1 NC_014550.1 transposase of ISAar40, IS3 family, IS3 group, orfA 3431999 9793544 AARI_36070 Arthrobacter arilaitensis Re117 transposase of ISAar40, IS3 family, IS3 group, orfA YP_003918232.1 3431673 D 861360 CDS YP_003918233.1 308178827 9793545 3431999..3432910 1 NC_014550.1 transposase of ISAar40, IS3 family, IS3 group, orfB 3432910 9793545 AARI_36080 Arthrobacter arilaitensis Re117 transposase of ISAar40, IS3 family, IS3 group, orfB YP_003918233.1 3431999 D 861360 CDS YP_003918234.1 308178828 9793546 complement(3433224..3433484) 1 NC_014550.1 signal peptide predicted by SignalP 3.0 HMM (probability: 1.000) with cleavage site probability 0.999 between position 30 and 31; hypothetical protein 3433484 9793546 AARI_30570 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918234.1 3433224 R 861360 CDS YP_003918235.1 308178829 9796498 complement(3434070..3434909) 1 NC_014550.1 transposase of ISAar3, IS3 family, IS407 group, orfB 3434909 9796498 AARI_36090 Arthrobacter arilaitensis Re117 transposase of ISAar3, IS3 family, IS407 group, orfB YP_003918235.1 3434070 R 861360 CDS YP_003918236.1 308178830 9793547 complement(3434939..3435217) 1 NC_014550.1 transposase of ISAar3, IS3 family, IS407 group, orfA 3435217 9793547 AARI_36100 Arthrobacter arilaitensis Re117 transposase of ISAar3, IS3 family, IS407 group, orfA YP_003918236.1 3434939 R 861360 CDS YP_003918237.1 308178831 9793549 complement(3435884..3437017) 1 NC_014550.1 identified by match to PF04055. Radical SAM proteins catalyse diverse reactions, including unusual methylations, isomerisation, sulphur insertion, ring formation, anaerobic oxidation and protein radical formation; radical SAM enzyme 3437017 9793549 AARI_30580 Arthrobacter arilaitensis Re117 radical SAM enzyme YP_003918237.1 3435884 R 861360 CDS YP_003918238.1 308178832 9796499 complement(3437319..3438437) 1 NC_014550.1 match to PR00420: Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature; aromatic-ring hydroxylase 3438437 9796499 AARI_30590 Arthrobacter arilaitensis Re117 aromatic-ring hydroxylase YP_003918238.1 3437319 R 861360 CDS YP_003918239.1 308178833 9796500 complement(3438430..3439143) 1 NC_014550.1 identified by match to protein domain PF08241; SAM-dependent methyltransferase 3439143 9796500 AARI_30600 Arthrobacter arilaitensis Re117 SAM-dependent methyltransferase YP_003918239.1 3438430 R 861360 CDS YP_003918240.1 308178834 9796501 complement(3439143..3440264) 1 NC_014550.1 identified by match to PIRSF000451. Type III polyketide synthases catalyse formation of structurally diverse polyketides; type III polyketide synthase 3440264 9796501 AARI_30610 Arthrobacter arilaitensis Re117 type III polyketide synthase YP_003918240.1 3439143 R 861360 CDS YP_003918241.1 308178835 9796502 3440432..3441097 1 NC_014550.1 identified by match to protein family PF00392. This family of regulatory proteins consists of the N-terminal HTH region of GntR-like bacterial transcription factors. At the C-terminus there is usually an effector- binding/oligomerisation domain. The GntR-like proteins can be divided into six sub-families: MocR, YtrR, FadR, AraR, HutC and PlmA. Many of these proteins have been shown experimentally to be autoregulatory, enabling the prediction of operator sites and the discovery of cis/trans relationships; GntR family transcriptional regulator 3441097 9796502 AARI_30620 Arthrobacter arilaitensis Re117 GntR family transcriptional regulator YP_003918241.1 3440432 D 861360 CDS YP_003918242.1 308178836 9796505 complement(3442149..3442811) 1 NC_014550.1 hypothetical protein 3442811 9796505 AARI_30650 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918242.1 3442149 R 861360 CDS YP_003918243.1 308178837 9796506 complement(3442896..3444065) 1 NC_014550.1 10 transmembrane helices predicted by TMHMM2.0; hypothetical protein 3444065 9796506 AARI_30660 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918243.1 3442896 R 861360 CDS YP_003918244.1 308178838 9796507 complement(3444118..3444861) 1 NC_014550.1 7 transmembrane helices predicted by TMHMM2.0; hypothetical protein 3444861 9796507 AARI_30670 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918244.1 3444118 R 861360 CDS YP_003918245.1 308178839 9796508 3444945..3446120 1 NC_014550.1 sarcosine oxidase catalyzes the oxidative demethylation of sarcosine and forms equimolar amounts of formaldehyde, glycine and hydrogen peroxide; monomeric sarcosine oxidase 3446120 9796508 AARI_30680 Arthrobacter arilaitensis Re117 monomeric sarcosine oxidase YP_003918245.1 3444945 D 861360 CDS YP_003918246.1 308178840 9796509 3446354..3446998 1 NC_014550.1 signal peptide predicted by SignalP 3.0 HMM (probability: 0.999) with cleavage site probability 0.472 between position 34 and 35; hypothetical protein 3446998 9796509 AARI_30690 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918246.1 3446354 D 861360 CDS YP_003918247.1 308178841 9796510 3447119..3447586 1 NC_014550.1 1 transmembrane helice predicted by TMHMM2.0; hypothetical protein 3447586 9796510 AARI_30700 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918247.1 3447119 D 861360 CDS YP_003918248.1 308178842 9796511 3447907..3448380 1 NC_014550.1 match to protein domain PF00746: Gram positive anchor. Surface proteins from Gram-positive cocci are covalently linked to the bacterial cell wall by sortase, a membrane-anchored transpeptidase that cleaves proteins between the threonine and the glycine of a conserved LPxTG motif, with the formation of a thioester between the conserved cysteine of sortase and the threonine carboxyl group. The newly liberated C-terminus of the threonine is transferred via an amide bond exchange to the amino group of the pentaglycine wall crossbridge, thereby tethering the C-terminus end of the surface protein to the bacterial peptidoglycan.The proteins that contain the conserved hexapeptide and hydrophobic anchor are diverse: they include M proteins, IgA and IgG binding proteins, fibronectin-binding proteins, wall-associated proteins, trypsin-resistant surface T protein, protein H precursor, etc.; cell surface protein 3448380 9796511 AARI_30710 Arthrobacter arilaitensis Re117 cell surface protein YP_003918248.1 3447907 D 861360 CDS YP_003918249.1 308178843 9796512 3448373..3448918 1 NC_014550.1 signal peptide predicted by SignalP 3.0 HMM (probability: 1.000) with cleavage site probability 0.431 between position 38 and 39; hypothetical protein 3448918 9796512 AARI_30720 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918249.1 3448373 D 861360 CDS YP_003918250.1 308178844 9796513 complement(3448942..3449970) 1 NC_014550.1 catalyzes the hydrolysis of glutamine to a glutamate and ammonia; glutaminase 3449970 glsA 9796513 glsA Arthrobacter arilaitensis Re117 glutaminase YP_003918250.1 3448942 R 861360 CDS YP_003918251.1 308178845 9793916 3450179..3450601 1 NC_014550.1 catalyzes the hydrolysis of the thioester bond in acyl-CoA thioesters; acyl-CoA thioester hydrolase 3450601 9793916 AARI_30740 Arthrobacter arilaitensis Re117 acyl-CoA thioester hydrolase YP_003918251.1 3450179 D 861360 CDS YP_003918252.1 308178846 9796514 3450800..3451219 1 NC_014550.1 lactoylglutathione lyase catalyzes the first step of the glyoxal pathway, the transformation of methylglyoxal and glutathione into S-lactoylglutathione which is then converted by glyoxalase II to lactic acid; lactoylglutathione lyase 3451219 9796514 AARI_30750 Arthrobacter arilaitensis Re117 lactoylglutathione lyase YP_003918252.1 3450800 D 861360 CDS YP_003918253.1 308178847 9796596 complement(3451227..3452066) 1 NC_014550.1 identified by match to protein family PF00657; GDSL-like lipase/esterase 3452066 9796596 AARI_30760 Arthrobacter arilaitensis Re117 GDSL-like lipase/esterase YP_003918253.1 3451227 R 861360 CDS YP_003918254.1 308178848 9796599 3452849..3454123 1 NC_014550.1 protein-histidine kinases are key elements in two- component signal transduction systems, which enable bacteria to sense, respond, and adapt to a wide range of environments, stressors, and growth conditions. 4 transmembrane helices predicted by TMHMM2.0; signal transduction histidine kinase 3454123 9796599 AARI_30790 Arthrobacter arilaitensis Re117 signal transduction histidine kinase YP_003918254.1 3452849 D 861360 CDS YP_003918255.1 308178849 9796600 3454111..3454800 1 NC_014550.1 response regulators are key elements in two- component signal transduction systems, which enable bacteria to sense, respond, and adapt to a wide range of environments, stressors, and growth conditions; two-component system response regulator 3454800 9796600 AARI_30800 Arthrobacter arilaitensis Re117 two-component system response regulator YP_003918255.1 3454111 D 861360 CDS YP_003918256.1 308178850 9796601 3454797..3455660 1 NC_014550.1 1 transmembrane helice predicted by TMHMM2.0; hypothetical protein 3455660 9796601 AARI_30810 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918256.1 3454797 D 861360 CDS YP_003918257.1 308178851 9796602 complement(3455787..3456614) 1 NC_014550.1 identified by match to protein family PF04012. This family includes PspA, which is a protein that suppresses sigma54-dependent transcription; pspA/IM30 family protein 3456614 9796602 AARI_30820 Arthrobacter arilaitensis Re117 pspA/IM30 family protein YP_003918257.1 3455787 R 861360 CDS YP_003918258.1 308178852 9796603 complement(3456699..3457418) 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily (TC 3. A.1.y.z). ABCISSE: ABC transporter, ATP-binding protein (ABC), NO family (NO family systems represent few ABC proteins with unknown function and which are apparently unrelated to existent families); ABC transporter ATP-binding subunit 3457418 9796603 AARI_30830 Arthrobacter arilaitensis Re117 ABC transporter ATP-binding subunit YP_003918258.1 3456699 R 861360 CDS YP_003918259.1 308178853 9796604 complement(3457531..3459429) 1 NC_014550.1 match to PR00420: Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature; aromatic-ring hydroxylase 3459429 9796604 AARI_30840 Arthrobacter arilaitensis Re117 aromatic-ring hydroxylase YP_003918259.1 3457531 R 861360 CDS YP_003918260.1 308178854 9793645 3459598..3460266 1 NC_014550.1 identified by match to PF09339: IclR helix-turn- helix domain. This family of bacterial transcriptional regulators groups several proteins, including gylR, a possible activator protein for the gylABX glycerol operon in Streptomyces, and iclR, the repressor of the acetate operon (also known as glyoxylate bypass operon) in Escherichia coli and Salmonella typhimurium; IclR family transcriptional regulator 3460266 9793645 AARI_30850 Arthrobacter arilaitensis Re117 IclR family transcriptional regulator YP_003918260.1 3459598 D 861360 CDS YP_003918261.1 308178855 9796605 complement(3460267..3460431) 1 NC_014550.1 hypothetical protein 3460431 9796605 AARI_30860 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918261.1 3460267 R 861360 CDS YP_003918262.1 308178856 9796606 3460651..3461421 1 NC_014550.1 hypothetical protein 3461421 9796606 AARI_30870 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918262.1 3460651 D 861360 CDS YP_003918263.1 308178857 9796607 complement(3461418..3462671) 1 NC_014550.1 major facilitator superfamily (TC 2.A.1.y.z). Identified by match to protein family PF07690 (Major Facilitator Superfamily); MFS superfamily transporter 3462671 9796607 AARI_30880 Arthrobacter arilaitensis Re117 MFS superfamily transporter YP_003918263.1 3461418 R 861360 CDS YP_003918264.1 308178858 9796608 complement(3462775..3463233) 1 NC_014550.1 match to protein domain PF09424. This domain is found in GatB and proteins related to bacterial Yqey. GatB transamidates Glu-tRNA to Gln-tRNA. The function of this domain is uncertain, but Yqey and its relatives may have a role in tRNA metabolism; Yqey-like protein 3463233 9796608 AARI_30890 Arthrobacter arilaitensis Re117 Yqey-like protein YP_003918264.1 3462775 R 861360 CDS YP_003918265.1 308178859 9796609 3463345..3464769 1 NC_014550.1 signal peptide predicted by SignalP 3.0 HMM (probability: 0.593) with cleavage site probability 0.268 between position 39 and 40; hypothetical protein 3464769 9796609 AARI_30900 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918265.1 3463345 D 861360 CDS YP_003918266.1 308178860 9796610 complement(3464766..3466046) 1 NC_014550.1 possible ATP-grasp enzyme; hypothetical protein 3466046 9796610 AARI_30910 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918266.1 3464766 R 861360 CDS YP_003918267.1 308178861 9796611 complement(3466060..3467202) 1 NC_014550.1 identified by match to protein family PF02388. The femAB operon codes for two nearly identical approximately 50-kDa proteins involved in the formation of the Staphylococcal pentaglycine interpeptide bridge in peptidoglycan. These proteins are also considered as a factor influencing the level of methicillin resistance; FemAB family protein 3467202 9796611 AARI_30920 Arthrobacter arilaitensis Re117 FemAB family protein YP_003918267.1 3466060 R 861360 CDS YP_003918268.1 308178862 9796612 3467299..3467628 1 NC_014550.1 hypothetical protein 3467628 9796612 AARI_30930 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918268.1 3467299 D 861360 CDS YP_003918269.1 308178863 9796613 3467688..3468002 1 NC_014550.1 match to PF00403: Heavy-metal-associated domain. This domain has been found in a number of heavy metal transport or detoxification proteins; metal binding protein 3468002 9796613 AARI_30940 Arthrobacter arilaitensis Re117 metal binding protein YP_003918269.1 3467688 D 861360 CDS YP_003918270.1 308178864 9796614 3468060..3470318 1 NC_014550.1 P-type ATPase (P-ATPase) superfamily (TC 3.A.3.y.z). Match to protein domain PF00403. Probably involved in export of cations such as Cu+ and Ag+; cation-transporting ATPase 3470318 9796614 AARI_30950 Arthrobacter arilaitensis Re117 cation-transporting ATPase YP_003918270.1 3468060 D 861360 CDS YP_003918271.1 308178865 9796615 3470968..3472470 1 NC_014550.1 amino acid-polyamine-organocation (APC) superfamily, amino acid transporter (AAT) family, D- Serine/D-alanine/glycine:H+ symporter (TC 2.A.3.1.7). Identified by similarity to protein SP:P0AAE0 (Escherichia coli); D-serine/D-alanine/glycine transporter 3472470 cycA 9796615 cycA Arthrobacter arilaitensis Re117 D-serine/D-alanine/glycine transporter YP_003918271.1 3470968 D 861360 CDS YP_003918272.1 308178866 9793770 3472517..3472849 1 NC_014550.1 hypothetical protein 3472849 9793770 AARI_30970 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918272.1 3472517 D 861360 CDS YP_003918273.1 308178867 9796617 complement(3473222..3474220) 1 NC_014550.1 9 transmembrane helices predicted by TMHMM2.0; hypothetical protein 3474220 9796617 AARI_30990 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918273.1 3473222 R 861360 CDS YP_003918274.1 308178868 9796618 3474335..3474886 1 NC_014550.1 hypothetical protein 3474886 9796618 AARI_31000 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918274.1 3474335 D 861360 CDS YP_003918275.1 308178869 9796619 3474974..3475282 1 NC_014550.1 hypothetical protein 3475282 9796619 AARI_31010 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918275.1 3474974 D 861360 CDS YP_003918276.1 308178870 9796620 complement(3475299..3475775) 1 NC_014550.1 identified by match to protein family TIGR01935: ribonuclease E inhibitor RraA.The Escherichia coli member of this family has been characterised as a regulator of RNase E, and its crystal structure has been analysed. It acts as a trans-acting modulator of RNA turnover, binding essential endonuclease RNase E and inhibiting RNA processing. RNase E forms the core of a large RNA- catalysis machine termed the degradosomes. RraA (and RraB) causes remodelling of degradosome composition, which is associated with alterations in RNA decay and global transcript abundance and as such is a bacterial mechanism for the regulation of RNA cleavage; ribonuclease activity regulator protein RraA 3475775 rraA 9796620 rraA Arthrobacter arilaitensis Re117 ribonuclease activity regulator protein RraA YP_003918276.1 3475299 R 861360 CDS YP_003918277.1 308178871 9794368 complement(3475868..3477361) 1 NC_014550.1 amino acid-polyamine-organocation (APC) superfamily (TC 2.A.3.y.z); amino acid transporter 3477361 9794368 AARI_31030 Arthrobacter arilaitensis Re117 amino acid transporter YP_003918277.1 3475868 R 861360 CDS YP_003918278.1 308178872 9796621 complement(3477470..3477712) 1 NC_014550.1 2 transmembrane helices predicted by TMHMM2.0; hypothetical protein 3477712 9796621 AARI_31040 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918278.1 3477470 R 861360 CDS YP_003918279.1 308178873 9796622 complement(3477802..3478395) 1 NC_014550.1 6 transmembrane helices predicted by TMHMM2.0; hypothetical protein 3478395 9796622 AARI_31050 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918279.1 3477802 R 861360 CDS YP_003918280.1 308178874 9796623 complement(3478451..3479671) 1 NC_014550.1 catalyses the conversion of L-lactate to pyruvate. Probable quinone-dependent lactate dehydrogenase, functionning when lactate is used as a carbon and energy source; L-lactate dehydrogenase 3479671 lldD 9796623 lldD Arthrobacter arilaitensis Re117 L-lactate dehydrogenase YP_003918280.1 3478451 R 861360 CDS YP_003918281.1 308178875 9794041 complement(3479702..3481015) 1 NC_014550.1 major facilitator superfamily (MFS), metabolite:H+ symporter (MHS) family (TC 2.A.1.6.z); MFS superfamily transporter 3481015 9794041 AARI_31070 Arthrobacter arilaitensis Re117 MFS superfamily transporter YP_003918281.1 3479702 R 861360 CDS YP_003918282.1 308178876 9796624 3481146..3481781 1 NC_014550.1 identified by match to protein family PF00392. This family of regulatory proteins consists of the N-terminal HTH region of GntR-like bacterial transcription factors. At the C-terminus there is usually an effector- binding/oligomerisation domain. The GntR-like proteins can be divided into six sub-families: MocR, YtrR, FadR, AraR, HutC and PlmA. Many of these proteins have been shown experimentally to be autoregulatory, enabling the prediction of operator sites and the discovery of cis/trans relationships; GntR family transcriptional regulator 3481781 9796624 AARI_31080 Arthrobacter arilaitensis Re117 GntR family transcriptional regulator YP_003918282.1 3481146 D 861360 CDS YP_003918283.1 308178877 9796625 complement(3481887..3483227) 1 NC_014550.1 Multi Antimicrobial Extrusion (MATE) Family protein (TC 2.A.66.1.z). Characterised members of the MATE family function as drug/sodium antiporters. These proteins mediate resistance to a wide range of cationic dyes, fluroquinolones, aminoglycosides and other structurally diverse antibodies and drugs; drug/sodium antiporter 3483227 9796625 AARI_31090 Arthrobacter arilaitensis Re117 drug/sodium antiporter YP_003918283.1 3481887 R 861360 CDS YP_003918284.1 308178878 9796626 3483433..3484221 1 NC_014550.1 hypothetical protein 3484221 9796626 AARI_31100 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918284.1 3483433 D 861360 CDS YP_003918285.1 308178879 9796627 complement(3484266..3485465) 1 NC_014550.1 major facilitator superfamily (TC 2.A.1.y.z). Identified by match to protein family PF07690; MFS superfamily transporter 3485465 9796627 AARI_31110 Arthrobacter arilaitensis Re117 MFS superfamily transporter YP_003918285.1 3484266 R 861360 CDS YP_003918286.1 308178880 9796628 complement(3485469..3486239) 1 NC_014550.1 identified by match to protein family PF02517: CAAX amino terminal protease family. Members of this family are probably proteases (after a prenyl group is attached to the Cys residue in the C-terminal CAAX motif of a protein, the AAX tripeptide is removed by one of the CAAX prenyl proteases). The family contains the Q03530 CAAX prenyl protease. 7 transmembrane helices predicted by TMHMM2.0; CAAX amino terminal protease family protein 3486239 9796628 AARI_31120 Arthrobacter arilaitensis Re117 CAAX amino terminal protease family protein YP_003918286.1 3485469 R 861360 CDS YP_003918287.1 308178881 9796629 complement(3486311..3487603) 1 NC_014550.1 match to PF08239: bacterial SH3 domain. A homologue of the SH3 domain has been found in a number of different bacterial proteins including glycyl-glycine endopeptidase, bacteriocin and some hypothetical proteins. Signal peptide predicted by SignalP 3.0 HMM (probability: 1.000) with cleavage site probability 0.812 between position 33 and 34; SH3 domain-containing protein 3487603 9796629 AARI_31130 Arthrobacter arilaitensis Re117 SH3 domain-containing protein YP_003918287.1 3486311 R 861360 CDS YP_003918288.1 308178882 9796630 complement(3488155..3490245) 1 NC_014550.1 TC 3.A.1.y.z. ABCISSE: ABC transporter, permease and ATP-binding protein (IM-ABC), DPL-family, LLP- subfamily (LIP-like exporters). The function of LIP-like exporters is presently unknown; ABC transporter ATPase and permease components 3490245 9796630 AARI_31140 Arthrobacter arilaitensis Re117 ABC transporter ATPase and permease components YP_003918288.1 3488155 R 861360 CDS YP_003918289.1 308178883 9796631 complement(3490246..3491979) 1 NC_014550.1 TC 3.A.1.y.z. ABCISSE: ABC transporter, permease and ATP-binding protein (IM-ABC), DPL-family, LLP- subfamily (LIP-like exporters). The function of LIP-like exporters is presently unknown; ABC transporter ATPase and permease components 3491979 9796631 AARI_31150 Arthrobacter arilaitensis Re117 ABC transporter ATPase and permease components YP_003918289.1 3490246 R 861360 CDS YP_003918290.1 308178884 9796634 complement(3493613..3494263) 1 NC_014550.1 match to protein family PF01329: pterin 4 alpha carbinolamine dehydratase; hypothetical protein 3494263 9796634 AARI_31180 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918290.1 3493613 R 861360 CDS YP_003918291.1 308178885 9796635 3494448..3494984 1 NC_014550.1 hypothetical protein 3494984 9796635 AARI_31190 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918291.1 3494448 D 861360 CDS YP_003918292.1 308178886 9796636 3494985..3495440 1 NC_014550.1 1 transmembrane helice predicted by TMHMM2.0; hypothetical protein 3495440 9796636 AARI_31200 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918292.1 3494985 D 861360 CDS YP_003918293.1 308178887 9796637 complement(3495488..3495814) 1 NC_014550.1 hypothetical protein 3495814 9796637 AARI_31210 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918293.1 3495488 R 861360 CDS YP_003918294.1 308178888 9796638 complement(3495817..3496410) 1 NC_014550.1 identified by match to protein family PF00857. This is a family of hydrolase enzymes. Isochorismatase, also known as 2,3 dihydro-2,3 dihydroxybenzoate synthase catalyses the conversion of isochorismate, in the presence of water, to 2,3-dihydroxybenzoate and pyruvate; isochorismatase family protein 3496410 9796638 AARI_31220 Arthrobacter arilaitensis Re117 isochorismatase family protein YP_003918294.1 3495817 R 861360 CDS YP_003918295.1 308178889 9796639 complement(3496612..3496860) 1 NC_014550.1 hypothetical protein 3496860 9796639 AARI_31230 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918295.1 3496612 R 861360 CDS YP_003918296.1 308178890 9796640 complement(3497062..3497310) 1 NC_014550.1 2 transmembrane helices predicted by TMHMM2.0; hypothetical protein 3497310 9796640 AARI_31240 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918296.1 3497062 R 861360 CDS YP_003918297.1 308178891 9796641 complement(3497338..3497493) 1 NC_014550.1 hypothetical protein 3497493 9796641 AARI_31250 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918297.1 3497338 R 861360 CDS YP_003918298.1 308178892 9796642 complement(3497522..3497788) 1 NC_014550.1 hypothetical protein 3497788 9796642 AARI_31260 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918298.1 3497522 R 861360 CDS YP_003918299.1 308178893 9796643 3498103..3499044 1 NC_014550.1 identified by match to PF00106. The short-chain dehydrogenases/reductases family (SDR) is a very large family of enzymes, most of which are known to be NAD- or NADP-dependent oxidoreductases; short-chain dehydrogenases/reductases family protein 3499044 9796643 AARI_31270 Arthrobacter arilaitensis Re117 short-chain dehydrogenases/reductases family protein YP_003918299.1 3498103 D 861360 CDS YP_003918300.1 308178894 9796644 complement(3499150..3500283) 1 NC_014550.1 3 transmembrane helices predicted by TMHMM2.0; hypothetical protein 3500283 9796644 AARI_31280 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918300.1 3499150 R 861360 CDS YP_003918301.1 308178895 9796645 3500404..3500685 1 NC_014550.1 hypothetical protein 3500685 9796645 AARI_31290 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918301.1 3500404 D 861360 CDS YP_003918302.1 308178896 9796646 3500728..3501900 1 NC_014550.1 identified by match to PF08240 and PF00107. Zn- dependent alcohol dehydrogenasescatalyse the following reaction: an alcohol + NAD(+) <=> an aldehyde or ketone + NADH; Zn-dependent alcohol dehydrogenase 3501900 9796646 AARI_31300 Arthrobacter arilaitensis Re117 Zn-dependent alcohol dehydrogenase YP_003918302.1 3500728 D 861360 CDS YP_003918303.1 308178897 9796649 3502945..3503202 1 NC_014550.1 2 transmembrane helices predicted by TMHMM2.0; hypothetical protein 3503202 9796649 AARI_31330 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918303.1 3502945 D 861360 CDS YP_003918304.1 308178898 9796650 3503399..3503875 1 NC_014550.1 peroxiredoxin protects cells against toxicity from reactive oxygen species by reducing and detoxifying hydroperoxides. The Bcp protein shows substrate selectivity toward fatty acid hydroperoxides rather than hydrogen peroxide or alkyl hydroperoxides; peroxiredoxin Bcp 3503875 bcp 9796650 bcp Arthrobacter arilaitensis Re117 peroxiredoxin Bcp YP_003918304.1 3503399 D 861360 CDS YP_003918305.1 308178899 9793708 complement(3503973..3505343) 1 NC_014550.1 succinate-semialdehyde dehydrogenase (NAD(P)(+)) reduces succinate semialdehyde into succinate. Involved in the degradation of gamma-aminobutyrate; succinate-semialdehyde dehydrogenase 3505343 gabD 9793708 gabD Arthrobacter arilaitensis Re117 succinate-semialdehyde dehydrogenase YP_003918305.1 3503973 R 861360 CDS YP_003918306.1 308178900 9793877 3505946..3507340 1 NC_014550.1 identified by match to PF03441 and PF00875. DNA photolyases are enzymes that bind to DNA containing pyrimidine dimers: on absorption of visible light, they catalyse dimer splitting into the constituent monomers, a process called photoreactivation. This is a DNA repair mechanism, repairing mismatched pyrimidine dimers induced by exposure to ultra-violet light; deoxyribodipyrimidine photo-lyase 3507340 9793877 AARI_31360 Arthrobacter arilaitensis Re117 deoxyribodipyrimidine photo-lyase YP_003918306.1 3505946 D 861360 CDS YP_003918307.1 308178901 9796651 3507726..3508160 1 NC_014550.1 3 transmembrane helices predicted by TMHMM2.0; hypothetical protein 3508160 9796651 AARI_31370 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918307.1 3507726 D 861360 CDS YP_003918308.1 308178902 9796652 3508157..3508831 1 NC_014550.1 5 transmembrane helices predicted by TMHMM2.0; hypothetical protein 3508831 9796652 AARI_31380 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918308.1 3508157 D 861360 CDS YP_003918309.1 308178903 9796653 complement(3508892..3509953) 1 NC_014550.1 synonym: acetoin reductase. Catalyzes the production of 2,3-butanediol from acetoin. Identified by similarity to protein SP:O34788 (Bacillus subtilis); (R,R)-butanediol dehydrogenase 3509953 bdh 9796653 bdh Arthrobacter arilaitensis Re117 (R,R)-butanediol dehydrogenase YP_003918309.1 3508892 R 861360 CDS YP_003918310.1 308178904 9793709 3510149..3510556 1 NC_014550.1 very short patch repair endonucleases recognises a TG mismatched base pair, generated after spontaneous deamination of methylated cytosines, and cleaves the phosphate backbone on the 5 prime side of the thymine; very short patch repair endonuclease 3510556 vsr 9793709 vsr Arthrobacter arilaitensis Re117 very short patch repair endonuclease YP_003918310.1 3510149 D 861360 CDS YP_003918311.1 308178905 9794501 3510736..3512019 1 NC_014550.1 major facilitator superfamily (TC 2.A.1.y.z). Identified by match to protein family PF07690; MFS superfamily transporter 3512019 9794501 AARI_31410 Arthrobacter arilaitensis Re117 MFS superfamily transporter YP_003918311.1 3510736 D 861360 CDS YP_003918312.1 308178906 9796654 3512236..3513777 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, peptide/opine/nickel uptake transporter (PepT) family (TC 3.A.1.5.z). ABCISSE: ABC transporter, binding protein (BP), OPN-family (oligopeptides and nickel), oligopeptides import; dipeptide/oligopeptide ABC transporter substrate-binding protein 3513777 9796654 AARI_31420 Arthrobacter arilaitensis Re117 dipeptide/oligopeptide ABC transporter substrate-binding protein YP_003918312.1 3512236 D 861360 CDS YP_003918313.1 308178907 9796655 3513779..3514732 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, peptide/opine/nickel uptake transporter (PepT) family (TC 3.A.1.5.z). ABCISSE: ABC transporter, permease (IM), OPN- family (oligopeptides and nickel), oligopeptides import; dipeptide/oligopeptide ABC transporter inner membrane subunit 3514732 9796655 AARI_31430 Arthrobacter arilaitensis Re117 dipeptide/oligopeptide ABC transporter inner membrane subunit YP_003918313.1 3513779 D 861360 CDS YP_003918314.1 308178908 9796656 3514713..3515576 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, peptide/opine/nickel uptake transporter (PepT) family (TC 3.A.1.5.z). ABCISSE: ABC transporter, permease (IM), OPN- family (oligopeptides and nickel), oligopeptides import; dipeptide/oligopeptide ABC transporter inner membrane subunit 3515576 9796656 AARI_31440 Arthrobacter arilaitensis Re117 dipeptide/oligopeptide ABC transporter inner membrane subunit YP_003918314.1 3514713 D 861360 CDS YP_003918315.1 308178909 9796657 3515569..3517107 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, peptide/opine/nickel uptake transporter (PepT) family (TC 3.A.1.5.z). ABCISSE: ABC transporter, fused ATP-binding protein (ABC2), OPN-family (oligopeptides and nickel), oligopeptides import; dipeptide/oligopeptide ABC transporter ATP-binding subunit 3517107 9796657 AARI_31450 Arthrobacter arilaitensis Re117 dipeptide/oligopeptide ABC transporter ATP-binding subunit YP_003918315.1 3515569 D 861360 CDS YP_003918316.1 308178910 9796658 complement(3517411..3517596) 1 NC_014550.1 1 transmembrane helice predicted by TMHMM2.0; hypothetical protein 3517596 9796658 AARI_31460 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918316.1 3517411 R 861360 CDS YP_003918317.1 308178911 9796659 3517661..3518422 1 NC_014550.1 identified by match to PF09339: IclR helix-turn- helix domain. This family of bacterial transcriptional regulators groups several proteins, including gylR, a possible activator protein for the gylABX glycerol operon in Streptomyces, and iclR, the repressor of the acetate operon (also known as glyoxylate bypass operon) in Escherichia coli and Salmonella typhimurium; IclR family transcriptional regulator 3518422 9796659 AARI_31470 Arthrobacter arilaitensis Re117 IclR family transcriptional regulator YP_003918317.1 3517661 D 861360 CDS YP_003918318.1 308178912 9796660 3519101..3520090 1 NC_014550.1 dihydroorotate oxidase catalyzes the fourth step in the de novo biosynthesis of pyrimidine, the conversion of dihydroorotate into orotate. In some organisms such as Bacillus subtilis, dihydroorotate oxidase is composed of two subunits: PyrDI and PyrDII; dihydroorotate oxidase catalytic subunit 3520090 pyrDI 9796660 pyrDI Arthrobacter arilaitensis Re117 dihydroorotate oxidase catalytic subunit YP_003918318.1 3519101 D 861360 CDS YP_003918319.1 308178913 9794268 3520087..3521361 1 NC_014550.1 major facilitator superfamily (TC 2.A.1.y.z). Identified by match to protein family PF07690; MFS superfamily transporter 3521361 9794268 AARI_31490 Arthrobacter arilaitensis Re117 MFS superfamily transporter YP_003918319.1 3520087 D 861360 CDS YP_003918320.1 308178914 9796661 3521420..3521947 1 NC_014550.1 hypothetical protein 3521947 9796661 AARI_31500 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918320.1 3521420 D 861360 CDS YP_003918321.1 308178915 9796662 3521940..3522443 1 NC_014550.1 hypothetical protein 3522443 9796662 AARI_31510 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918321.1 3521940 D 861360 CDS YP_003918322.1 308178916 9796663 3522511..3523725 1 NC_014550.1 allantoate deiminase catalyses the conversion of allantoate in ammonia, carbon dioxide andureidoglycolate. Involved in purine degradation; allantoate deiminase 3523725 9796663 AARI_31520 Arthrobacter arilaitensis Re117 allantoate deiminase YP_003918322.1 3522511 D 861360 CDS YP_003918323.1 308178917 9796664 3523735..3524634 1 NC_014550.1 dihydroorotate oxidase catalyzes the fourth step in the de novo biosynthesis of pyrimidine, the conversion of dihydroorotate into orotate. In some organisms such as Bacillus subtilis, dihydroorotate oxidase is composed of two subunits: PyrDI and PyrDII; dihydroorotate oxidase electron transfer subunit 3524634 pyrDII 9796664 pyrDII Arthrobacter arilaitensis Re117 dihydroorotate oxidase electron transfer subunit YP_003918323.1 3523735 D 861360 CDS YP_003918324.1 308178918 9794269 3524631..3525956 1 NC_014550.1 catalyzes the third step in the de novo biosynthesis of pyrimidine, the conversion of N-carbamoyl- L-aspartate into dihydroorotate; dihydroorotase 3525956 pyrC 9794269 pyrC Arthrobacter arilaitensis Re117 dihydroorotase YP_003918324.1 3524631 D 861360 CDS YP_003918325.1 308178919 9794266 3525964..3527418 1 NC_014550.1 catalyzes the reversible conversion of aspartate to fumarate and ammonia; aspartate ammonia-lyase 3527418 aspA 9794266 aspA Arthrobacter arilaitensis Re117 aspartate ammonia-lyase YP_003918325.1 3525964 D 861360 CDS YP_003918326.1 308178920 9793696 3527634..3528473 1 NC_014550.1 identified by similarity to protein SP:Q01269 (Pseudomonas aeruginosa). Forms an alternative pathway for phenylalanine biosynthesis. Can catalyze two reactions: prephenate dehydratase (EC 4.2.1.51: Prephenate = phenylpyruvate + H2O + CO2) and arogenate dehydratase (EC 4.2.1.91: L-arogenate = L-phenylalanine + H2O + CO2); cyclohexadienyl dehydratase 3528473 pheC 9793696 pheC Arthrobacter arilaitensis Re117 cyclohexadienyl dehydratase YP_003918326.1 3527634 D 861360 CDS YP_003918327.1 308178921 9794203 complement(3528577..3529350) 1 NC_014550.1 identified by match to PF00106. The short-chain dehydrogenases/reductases family (SDR) is a very large family of enzymes, most of which are known to be NAD- or NADP-dependent oxidoreductases; short-chain dehydrogenases/reductases family protein 3529350 9794203 AARI_31570 Arthrobacter arilaitensis Re117 short-chain dehydrogenases/reductases family protein YP_003918327.1 3528577 R 861360 CDS YP_003918328.1 308178922 9796665 3529596..3530933 1 NC_014550.1 major facilitator superfamily (MFS), metabolite:H+ symporter (MHS) family (TC 2.A.1.6.z); MFS superfamily transporter 3530933 9796665 AARI_31580 Arthrobacter arilaitensis Re117 MFS superfamily transporter YP_003918328.1 3529596 D 861360 CDS YP_003918329.1 308178923 9796666 3530987..3531871 1 NC_014550.1 identified by match to PF00456: transketolase, thiamine diphosphate binding domain; transketolase subunit A 3531871 9796666 AARI_31590 Arthrobacter arilaitensis Re117 transketolase subunit A YP_003918329.1 3530987 D 861360 CDS YP_003918330.1 308178924 9796667 3531872..3532864 1 NC_014550.1 identified by match to PF02779 (transketolase, pyrimidine binding domain) and PF02780 (transketolase, C- terminal domain); transketolase subunit B 3532864 9796667 AARI_31600 Arthrobacter arilaitensis Re117 transketolase subunit B YP_003918330.1 3531872 D 861360 CDS YP_003918331.1 308178925 9796668 3532988..3533650 1 NC_014550.1 identified by match to protein family PF00392. This family of regulatory proteins consists of the N-terminal HTH region of GntR-like bacterial transcription factors. At the C-terminus there is usually an effector- binding/oligomerisation domain. The GntR-like proteins can be divided into six sub-families: MocR, YtrR, FadR, AraR, HutC and PlmA. Many of these proteins have been shown experimentally to be autoregulatory, enabling the prediction of operator sites and the discovery of cis/trans relationships; GntR family transcriptional regulator 3533650 9796668 AARI_31610 Arthrobacter arilaitensis Re117 GntR family transcriptional regulator YP_003918331.1 3532988 D 861360 CDS YP_003918332.1 308178926 9796669 3534299..3534952 1 NC_014550.1 match to PF01381: helix-turn-helix. This is large family of DNA binding helix-turn helix proteins that include a bacterial plasmid copy control protein, bacterial methylases, various bacteriophage transcription control proteins and a vegetative specific protein from Dictyostelium discoideum (Slime mould); hypothetical protein 3534952 9796669 AARI_31620 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918332.1 3534299 D 861360 CDS YP_003918333.1 308178927 9796670 3534949..3536235 1 NC_014550.1 identified by match to PF07804 (HipA-like C- terminal domain) and PF07805 (HipA-like N-terminal domain). The HipA protein is known to be involved in high- frequency persistence to the lethal effects of inhibition of either DNA or peptidoglycan synthesis. When expressed alone, it is toxic to bacterial cells but it is usually tightly associated with HipB and the HipA-HipB complex may be involved in autoregulation of the hip operon. The hip proteins may be involved in cell division control and may interact with cell division genes or their products; HipA-like protein 3536235 9796670 AARI_31630 Arthrobacter arilaitensis Re117 HipA-like protein YP_003918333.1 3534949 D 861360 CDS YP_003918334.1 308178928 9796671 complement(3536325..3537398) 1 NC_014550.1 match to protein family PF00724: NADH:flavin oxidoreductase / NADH oxidase family; flavin oxidoreductase 3537398 9796671 AARI_31640 Arthrobacter arilaitensis Re117 flavin oxidoreductase YP_003918334.1 3536325 R 861360 CDS YP_003918335.1 308178929 9796672 complement(3537564..3538316) 1 NC_014550.1 identified by match to PF00106. The short-chain dehydrogenases/reductases family (SDR) is a very large family of enzymes, most of which are known to be NAD- or NADP-dependent oxidoreductases; short-chain dehydrogenases/reductases family protein 3538316 9796672 AARI_31650 Arthrobacter arilaitensis Re117 short-chain dehydrogenases/reductases family protein YP_003918335.1 3537564 R 861360 CDS YP_003918336.1 308178930 9796673 complement(3538442..3539824) 1 NC_014550.1 TC 3.A.1.y.z. ABCISSE: ABC transporter, fused ATP- binding protein (ABC2), CBY-family (Cobalt uptake, unknown), Y179-subfamily (CBU-like systems). The function of CBU-like systems is unknown; ABC transporter ATP-binding subunit 3539824 9796673 AARI_31660 Arthrobacter arilaitensis Re117 ABC transporter ATP-binding subunit YP_003918336.1 3538442 R 861360 CDS YP_003918337.1 308178931 9796674 complement(3539827..3540585) 1 NC_014550.1 TC 3.A.1.y.z. ABCISSE: ABC transporter, permease (IM), CBY-family (Cobalt uptake, unknown), Y179-subfamily (CBU-like systems). The function of CBU-like systems is unknown; ABC transporter inner membrane subunit 3540585 9796674 AARI_31670 Arthrobacter arilaitensis Re117 ABC transporter inner membrane subunit YP_003918337.1 3539827 R 861360 CDS YP_003918338.1 308178932 9796675 complement(3540596..3541342) 1 NC_014550.1 6 transmembrane helices predicted by TMHMM2.0; hypothetical protein 3541342 9796675 AARI_31680 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918338.1 3540596 R 861360 CDS YP_003918339.1 308178933 9796676 complement(3541523..3542620) 1 NC_014550.1 catalyzes the hydrolysis of all of the commonly occuring purine and pyrimidine nucleosides into ribose and the associated base, but has a preference for inosine and uridine as substrates; purine nucleosidase 3542620 9796676 AARI_31690 Arthrobacter arilaitensis Re117 purine nucleosidase YP_003918339.1 3541523 R 861360 CDS YP_003918340.1 308178934 9796758 complement(3542683..3545670) 1 NC_014550.1 possible DNA or RNA helicase; ATP-dependent helicase 3545670 9796758 AARI_31700 Arthrobacter arilaitensis Re117 ATP-dependent helicase YP_003918340.1 3542683 R 861360 CDS YP_003918341.1 308178935 9796759 complement(3545667..3546059) 1 NC_014550.1 identified by match to PF00293. Members of the Nudix hydrolase superfamily catalyze the hydrolysis of nucleoside diphosphates linked to other moieties. Substrates of nudix hydrolases include intact and oxidatively damaged nucleoside triphosphates, dinucleoside polyphosphates, nucleotide-sugars and dinucleotide enzymes. These substrates are metabolites or cell signaling molecules that require regulation during different stages of the cell cycle or during periods of stress. In general, the role of the nudix hydrolase is to sanitize the nucleotide pools and to maintain cell viability, thereby serving as surveillance and house- cleaning enzymes; NUDIX hydrolase 3546059 9796759 AARI_31710 Arthrobacter arilaitensis Re117 NUDIX hydrolase YP_003918341.1 3545667 R 861360 CDS YP_003918342.1 308178936 9796760 complement(3546279..3547601) 1 NC_014550.1 major facilitator superfamily (MFS), Anion:Cation Symporter (ACS) Family, galactonate uptake (TC 2.A.1.14.7); D-galactonate transporter 3547601 dgoT 9796760 dgoT Arthrobacter arilaitensis Re117 D-galactonate transporter YP_003918342.1 3546279 R 861360 CDS YP_003918343.1 308178937 9793808 complement(3547607..3548755) 1 NC_014550.1 catalyzes the first reaction in the D-galactonate catabolic pathway; galactonate dehydratase 3548755 dgoD 9793808 dgoD Arthrobacter arilaitensis Re117 galactonate dehydratase YP_003918343.1 3547607 R 861360 CDS YP_003918344.1 308178938 9793806 complement(3548752..3549396) 1 NC_014550.1 catalyzes the third reaction in the D-galactonate catabolic pathway; 2-dehydro-3-deoxy-6-phosphogalactonate aldolase 3549396 dgoA 9793806 dgoA Arthrobacter arilaitensis Re117 2-dehydro-3-deoxy-6-phosphogalactonate aldolase YP_003918344.1 3548752 R 861360 CDS YP_003918345.1 308178939 9793805 complement(3549438..3550430) 1 NC_014550.1 catalyzes the second reaction in the D-galactonate catabolic pathway; 2-dehydro-3-deoxygalactonokinase 3550430 dgoK 9793805 dgoK Arthrobacter arilaitensis Re117 2-dehydro-3-deoxygalactonokinase YP_003918345.1 3549438 R 861360 CDS YP_003918346.1 308178940 9793807 3550581..3551378 1 NC_014550.1 identified by match to PF09339: IclR helix-turn- helix domain. This family of bacterial transcriptional regulators groups several proteins, including gylR, a possible activator protein for the gylABX glycerol operon in Streptomyces, and iclR, the repressor of the acetate operon (also known as glyoxylate bypass operon) in Escherichia coli and Salmonella typhimurium; IclR family transcriptional regulator 3551378 9793807 AARI_31760 Arthrobacter arilaitensis Re117 IclR family transcriptional regulator YP_003918346.1 3550581 D 861360 CDS YP_003918347.1 308178941 9793551 3552452..3553156 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, peptide/opine/nickel uptake transporter (PepT) family (TC 3.A.1.5.z). ABCISSE: ABC transporter, ATP-binding protein (ABC), OPN-family (oligopeptides and nickel); ABC transporter ATP-binding subunit 3553156 9793551 AARI_31770 Arthrobacter arilaitensis Re117 ABC transporter ATP-binding subunit YP_003918347.1 3552452 D 861360 CDS YP_003918348.1 308178942 9796762 3553153..3553857 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, peptide/opine/nickel uptake transporter (PepT) family (TC 3.A.1.5.z). ABCISSE: ABC transporter, ATP-binding protein (ABC), OPN-family (oligopeptides and nickel); ABC transporter ATP-binding subunit 3553857 9796762 AARI_31780 Arthrobacter arilaitensis Re117 ABC transporter ATP-binding subunit YP_003918348.1 3553153 D 861360 CDS YP_003918349.1 308178943 9796763 3553854..3555371 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, peptide/opine/nickel uptake transporter (PepT) family (TC 3.A.1.5.z). ABCISSE: ABC transporter, binding protein (BP), OPN-family (oligopeptides and nickel); ABC transporter substrate-binding protein 3555371 9796763 AARI_31790 Arthrobacter arilaitensis Re117 ABC transporter substrate-binding protein YP_003918349.1 3553854 D 861360 CDS YP_003918350.1 308178944 9796764 3555384..3557228 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, peptide/opine/nickel uptake transporter (PepT) family (TC 3.A.1.5.z). ABCISSE: ABC transporter, permease (IM), OPN- family (oligopeptides and nickel); ABC transporter inner membrane subunit 3557228 9796764 AARI_31800 Arthrobacter arilaitensis Re117 ABC transporter inner membrane subunit YP_003918350.1 3555384 D 861360 CDS YP_003918351.1 308178945 9796765 complement(3557332..3558417) 1 NC_014550.1 possible glutamate--cysteine ligase (6.3.2.2). Match to protein family PF04107: glutamate-cysteine ligase family 2(GCS2); carboxylate-amine ligase 3558417 9796765 AARI_31810 Arthrobacter arilaitensis Re117 carboxylate-amine ligase YP_003918351.1 3557332 R 861360 CDS YP_003918352.1 308178946 9796766 3558805..3559563 1 NC_014550.1 hypothetical protein 3559563 9796766 AARI_31820 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918352.1 3558805 D 861360 CDS YP_003918353.1 308178947 9796767 3559823..3560101 1 NC_014550.1 1 transmembrane helice predicted by TMHMM2.0; hypothetical protein 3560101 9796767 AARI_31830 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918353.1 3559823 D 861360 CDS YP_003918354.1 308178948 9796768 complement(3560124..3560432) 1 NC_014550.1 hypothetical protein 3560432 9796768 AARI_31840 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918354.1 3560124 R 861360 CDS YP_003918355.1 308178949 9796769 complement(3560614..3560814) 1 NC_014550.1 identified by match to SM00705: CDGSH-type zinc finger domain. Zinc finger (Znf) domains are relatively small protein motifs that bind one or more zinc atoms, and which usually contain multiple finger-like protrusions that make tandem contacts with their target molecule. They were first identified as a DNA-binding motif in transcription factor TFIIIA from Xenopus laevis, however they are now recognised to bind DNA, RNA, protein and/or lipid substrates. The CDGSH-type zinc finger contains a CDGSH sequence motif (although the Ser residue can also be an Ala or Thr), and is found in proteins from a wide range of organisms with the exception of fungi. Proteins carrying this domain include ferredoxin-dependent glutamate synthase. CDGSH-type domains are also found in the iron-containing outer membrane protein mitoNEET. MitoNEET contains the conserved sequence C-X-C-X2-(S/T)-X3- P-X-C-D-G-(S/A/T)-H, a defining feature of CDGSH domains, and is likely involved in iron binding rather than zinc binding; zinc finger domain-containing protein 3560814 9796769 AARI_31850 Arthrobacter arilaitensis Re117 zinc finger domain-containing protein YP_003918355.1 3560614 R 861360 CDS YP_003918356.1 308178950 9796770 complement(3560811..3561839) 1 NC_014550.1 hypothetical protein 3561839 9796770 AARI_31860 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918356.1 3560811 R 861360 CDS YP_003918357.1 308178951 9796771 complement(3562052..3562606) 1 NC_014550.1 match to protein family TIGR01382. A role in the degradation of small peptides has been suggested; PfpI family intracellular protease 3562606 9796771 AARI_31870 Arthrobacter arilaitensis Re117 PfpI family intracellular protease YP_003918357.1 3562052 R 861360 CDS YP_003918358.1 308178952 9796772 3563256..3563696 1 NC_014550.1 hypothetical protein 3563696 9796772 AARI_31880 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918358.1 3563256 D 861360 CDS YP_003918359.1 308178953 9796773 3564041..3564202 1 NC_014550.1 hypothetical protein 3564202 9796773 AARI_31890 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918359.1 3564041 D 861360 CDS YP_003918360.1 308178954 9796774 3564289..3565560 1 NC_014550.1 NhaA Na+:H+antiporter (NhaA) family (TC 2.A.33.y.z). Na(+)/H(+) antiporter extrudes sodium in exchange for external protons. Active at alkaline pH. In E. coli, NhaA protein probably functions in the regulation of the internal pH when the external pH is alkaline. It also uses the H+ gradient to expel Na+ from the cell. Its activity is highly pH dependent; Na+/H+ antiporter NhaA 3565560 nhaA 9796774 nhaA Arthrobacter arilaitensis Re117 Na+/H+ antiporter NhaA YP_003918360.1 3564289 D 861360 CDS YP_003918361.1 308178955 9794140 complement(3565639..3566781) 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, phosphate uptake transporter (PhoT) family, phosphate transporter (TC 3.A.1.7.2). ABCISSE: ABC transporter, binding protein (BP), MOI-family, phosphate import. Part of an ABC transporter complex involved in phosphate import; phosphate ABC transporter substrate-binding protein PstS 3566781 pstS 9794140 pstS Arthrobacter arilaitensis Re117 phosphate ABC transporter substrate-binding protein PstS YP_003918361.1 3565639 R 861360 CDS YP_003918362.1 308178956 9794239 3567297..3567557 1 NC_014550.1 3 transmembrane helices predicted by TMHMM2.0; hypothetical protein 3567557 9794239 AARI_31920 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918362.1 3567297 D 861360 CDS YP_003918363.1 308178957 9796775 complement(3567702..3568133) 1 NC_014550.1 hypothetical protein 3568133 9796775 AARI_31930 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918363.1 3567702 R 861360 CDS YP_003918364.1 308178958 9796776 3568578..3569717 1 NC_014550.1 possible glutamate--cysteine ligase (6.3.2.2). Match to protein family PF04107: glutamate-cysteine ligase family 2(GCS2); carboxylate-amine ligase 3569717 9796776 AARI_31940 Arthrobacter arilaitensis Re117 carboxylate-amine ligase YP_003918364.1 3568578 D 861360 CDS YP_003918365.1 308178959 9796777 complement(3569738..3571171) 1 NC_014550.1 signal peptide predicted by SignalP 3.0 HMM (probability: 0.502) with cleavage site probability 0.387 between position 20 and 21; hypothetical protein 3571171 9796777 AARI_31950 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918365.1 3569738 R 861360 CDS YP_003918366.1 308178960 9796778 complement(3571214..3571636) 1 NC_014550.1 ArsC reduces arsenate [As(V)] to arsenite [As(III)] and dephosphorylates tyrosine phosphorylated proteins, low- MW aryl phosphates and natural and synthetic acyl phosphates. Could switch between different functions in different circumstances; arsenate reductase 3571636 arsC 9796778 arsC Arthrobacter arilaitensis Re117 arsenate reductase YP_003918366.1 3571214 R 861360 CDS YP_003918367.1 308178961 9793692 complement(3571642..3572724) 1 NC_014550.1 Arsenical Resistance-3 (ACR3) Family, ArsB arsenite/antimonite exporter (TC 2.A.59.1.2). Identified by similarity to protein SP: P45946 (Bacillus subtilis). Confers resistance to arsenite by allowing cells to extrude this compound; arsenite resistance protein ArsB 3572724 arsB 9793692 arsB Arthrobacter arilaitensis Re117 arsenite resistance protein ArsB YP_003918367.1 3571642 R 861360 CDS YP_003918368.1 308178962 9793691 3572836..3573210 1 NC_014550.1 identified by match to PF01022: bacterial regulatory protein, ArsR family. ArsR-family transcriptional regulators include several proteins that appear to dissociate from DNA in the presence of metal ions; ArsR family transcriptional regulator 3573210 9793691 AARI_31980 Arthrobacter arilaitensis Re117 ArsR family transcriptional regulator YP_003918368.1 3572836 D 861360 CDS YP_003918369.1 308178963 9796779 complement(3573374..3573637) 1 NC_014550.1 identified by match to SM00705: CDGSH-type zinc finger domain. Zinc finger (Znf) domains are relatively small protein motifs that bind one or more zinc atoms, and which usually contain multiple finger-like protrusions that make tandem contacts with their target molecule. They were first identified as a DNA-binding motif in transcription factor TFIIIA from Xenopus laevis, however they are now recognised to bind DNA, RNA, protein and/or lipid substrates. The CDGSH-type zinc finger contains a CDGSH sequence motif (although the Ser residue can also be an Ala or Thr), and is found in proteins from a wide range of organisms with the exception of fungi. Proteins carrying this domain include ferredoxin-dependent glutamate synthase. CDGSH-type domains are also found in the iron-containing outer membrane protein mitoNEET. MitoNEET contains the conserved sequence C-X-C-X2-(S/T)-X3- P-X-C-D-G-(S/A/T)-H, a defining feature of CDGSH domains, and is likely involved in iron binding rather than zinc binding; zinc finger domain-containing protein 3573637 9796779 AARI_31990 Arthrobacter arilaitensis Re117 zinc finger domain-containing protein YP_003918369.1 3573374 R 861360 CDS YP_003918370.1 308178964 9796780 complement(3573634..3574497) 1 NC_014550.1 hypothetical protein 3574497 9796780 AARI_32000 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918370.1 3573634 R 861360 CDS YP_003918371.1 308178965 9796781 3574782..3575282 1 NC_014550.1 hypothetical protein 3575282 9796781 AARI_32010 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918371.1 3574782 D 861360 CDS YP_003918372.1 308178966 9796782 3575634..3575849 1 NC_014550.1 hypothetical protein 3575849 9796782 AARI_32020 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918372.1 3575634 D 861360 CDS YP_003918373.1 308178967 9796783 complement(3575972..3576934) 1 NC_014550.1 4 transmembrane helices predicted by TMHMM2.0; hypothetical protein 3576934 9796783 AARI_32030 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918373.1 3575972 R 861360 CDS YP_003918374.1 308178968 9796784 complement(3576931..3577362) 1 NC_014550.1 hypothetical protein 3577362 9796784 AARI_32040 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918374.1 3576931 R 861360 CDS YP_003918375.1 308178969 9796785 complement(3577499..3578578) 1 NC_014550.1 transposase of ISAar18, IS110 family 3578578 9796785 AARI_36140 Arthrobacter arilaitensis Re117 transposase of ISAar18, IS110 family YP_003918375.1 3577499 R 861360 CDS YP_003918376.1 308178970 9793552 3579025..3580221 1 NC_014550.1 transposase of ISAar17, IS110 family 3580221 9793552 AARI_36150 Arthrobacter arilaitensis Re117 transposase of ISAar17, IS110 family YP_003918376.1 3579025 D 861360 CDS YP_003918377.1 308178971 9796786 3580868..3582076 1 NC_014550.1 major facilitator superfamily (TC 2.A.1.y.z). Identified by match to protein family PF07690; MFS superfamily transporter 3582076 9796786 AARI_32060 Arthrobacter arilaitensis Re117 MFS superfamily transporter YP_003918377.1 3580868 D 861360 CDS YP_003918378.1 308178972 9796787 complement(3582146..3583189) 1 NC_014550.1 possible transporter. Match to PF00571 (CBS domain pair); CBS domain-containing transporter 3583189 9796787 AARI_32070 Arthrobacter arilaitensis Re117 CBS domain-containing transporter YP_003918378.1 3582146 R 861360 CDS YP_003918379.1 308178973 9796788 complement(3583186..3584532) 1 NC_014550.1 possible transporter. Match to PF00571 (CBS domain pair); CBS domain-containing transporter 3584532 9796788 AARI_32080 Arthrobacter arilaitensis Re117 CBS domain-containing transporter YP_003918379.1 3583186 R 861360 CDS YP_003918380.1 308178974 9796789 3584862..3586094 1 NC_014550.1 glutaminase catalyzes the hydrolysis of glutamine to a glutamate and ammonia; glutaminase 3586094 9796789 AARI_32090 Arthrobacter arilaitensis Re117 glutaminase YP_003918380.1 3584862 D 861360 CDS YP_003918381.1 308178975 9796790 complement(3586103..3588007) 1 NC_014550.1 N-terminal section of the protein: COG4781 (membrane domain of membrane-anchored glycerophosphoryl diester phosphodiesterase); 7 transmembrane helices predicted by TMHMM2.0. C-terminal section of the protein: match to PF03009 (glycerophosphoryl diester phosphodiesterase family). Escherichia coli has two sequence related isozymes of glycerophosphoryl diester phosphodiesterase (GDPD) - periplasmic and cytosolic. glycerophosphoryl diester phosphodiesterases display broad specificity for glycerophosphodiesters; glycerophosphocholine, glycerophosphoethanolamine, glycerophosphoglycerol, and bis(glycerophosphoglycerol); periplasmic glycerophosphoryl diester phosphodiesterase 3588007 9796790 AARI_32100 Arthrobacter arilaitensis Re117 periplasmic glycerophosphoryl diester phosphodiesterase YP_003918381.1 3586103 R 861360 CDS YP_003918382.1 308178976 9796791 complement(3588128..3588598) 1 NC_014550.1 signal peptide predicted by SignalP 3.0 HMM (probability: 0.992) with cleavage site probability 0.758 between position 37 and 38; hypothetical protein 3588598 9796791 AARI_32110 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918382.1 3588128 R 861360 CDS YP_003918383.1 308178977 9796792 3588925..3589842 1 NC_014550.1 identified by match to PF00296. Bacterial luciferase is a flavin monooxygenase that catalyses the oxidation of long-chain aldehydes and releases energy in the form of visible light, and which uses flavin as a substrate rather than a cofactor. There are structural similarities between bacterial luciferase and nonfluorescent flavoproteins (LuxF, FP390), alkanesulfonate monooxygenase (SsuD), and coenzyme F420- dependent terahydromethanopterin reductase, which make up clearly related families with somewhat different folds; luciferase-like monooxygenase 3589842 9796792 AARI_32120 Arthrobacter arilaitensis Re117 luciferase-like monooxygenase YP_003918383.1 3588925 D 861360 CDS YP_003918384.1 308178978 9796793 complement(3590116..3590808) 1 NC_014550.1 hypothetical protein 3590808 9796793 AARI_32130 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918384.1 3590116 R 861360 CDS YP_003918385.1 308178979 9796794 complement(3591039..3592436) 1 NC_014550.1 transposase of ISAar12, IS1380 family 3592436 9796794 AARI_36160 Arthrobacter arilaitensis Re117 transposase of ISAar12, IS1380 family YP_003918385.1 3591039 R 861360 CDS YP_003918386.1 308178980 9793554 complement(3593130..3594275) 1 NC_014550.1 identified by match to protein family PF00246: zinc carboxypeptidase; carboxypeptidase 3594275 9793554 AARI_32140 Arthrobacter arilaitensis Re117 carboxypeptidase YP_003918386.1 3593130 R 861360 CDS YP_003918387.1 308178981 9796795 complement(3594275..3594760) 1 NC_014550.1 hypothetical protein 3594760 9796795 AARI_32150 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918387.1 3594275 R 861360 CDS YP_003918388.1 308178982 9796796 complement(3594762..3596309) 1 NC_014550.1 Solute:Sodium Symporter (SSS) family (2.A.21.y.z). Members of the SSS family catalyze solute:Na+ symport. The solutes transported may be sugars, amino acids, organo cations such as choline, nucleosides, inositols, vitamins, urea or anions, depending on the system; Na+/solute symporter 3596309 9796796 AARI_32160 Arthrobacter arilaitensis Re117 Na+/solute symporter YP_003918388.1 3594762 R 861360 CDS YP_003918389.1 308178983 9796797 3596537..3598138 1 NC_014550.1 identified by match to PF07905: purine catabolism regulatory protein-like family. The bacterial proteins found in this family are similar to the purine catabolism regulatory protein expressed by Bacillus subtilis (PucR, O32138). PucR is thought to be a transcriptional activator involved in the induction of the purine degradation pathway, and may contain a LysR-like DNA-binding domain. It is similar to LysR-type regulators in that it represses its own expression. The other members of this family are also annotated as being regulatory proteins; transcriptional regulator 3598138 9796797 AARI_32170 Arthrobacter arilaitensis Re117 transcriptional regulator YP_003918389.1 3596537 D 861360 CDS YP_003918390.1 308178984 9796798 complement(3598230..3599102) 1 NC_014550.1 catalyses the following reaction: 10- formyltetrahydrofolate + H(2)O <=> formate + tetrahydrofolate; formyltetrahydrofolate deformylase 3599102 purU 9796798 purU Arthrobacter arilaitensis Re117 formyltetrahydrofolate deformylase YP_003918390.1 3598230 R 861360 CDS YP_003918391.1 308178985 9794259 3599543..3600211 1 NC_014550.1 identified by match to protein family PF00392. This family of regulatory proteins consists of the N-terminal HTH region of GntR-like bacterial transcription factors. At the C-terminus there is usually an effector- binding/oligomerisation domain. The GntR-like proteins can be divided into six sub-families: MocR, YtrR, FadR, AraR, HutC and PlmA. Many of these proteins have been shown experimentally to be autoregulatory, enabling the prediction of operator sites and the discovery of cis/trans relationships; GntR family transcriptional regulator 3600211 9794259 AARI_32190 Arthrobacter arilaitensis Re117 GntR family transcriptional regulator YP_003918391.1 3599543 D 861360 CDS YP_003918392.1 308178986 9796801 complement(3601800..3602096) 1 NC_014550.1 hypothetical protein 3602096 9796801 AARI_32220 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918392.1 3601800 R 861360 CDS YP_003918393.1 308178987 9796802 complement(3602199..3602729) 1 NC_014550.1 hypothetical protein 3602729 9796802 AARI_32230 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918393.1 3602199 R 861360 CDS YP_003918394.1 308178988 9796803 complement(3602809..3605301) 1 NC_014550.1 C-terminal part of the protein: Sigma 70 regions 2 and 4 (PF04542, PF08281). Presence of numerous PT repeats (XPTX) at the C-terminal part of the protein; RNA polymerase sigma factor 3605301 9796803 AARI_32240 Arthrobacter arilaitensis Re117 RNA polymerase sigma factor YP_003918394.1 3602809 R 861360 CDS YP_003918395.1 308178989 9796804 complement(3605711..3607018) 1 NC_014550.1 1 transmembrane helice predicted by TMHMM2.0; hypothetical protein 3607018 9796804 AARI_32250 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918395.1 3605711 R 861360 CDS YP_003918396.1 308178990 9796805 complement(3607015..3608379) 1 NC_014550.1 match to PF00535: glycosyl transferase family 2. This domain is found in a diverse family of glycosyl transferases that transfer the sugar from UDP-glucose, UDP- N-acetyl-galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids; glycosyl transferase family 2 3608379 9796805 AARI_32260 Arthrobacter arilaitensis Re117 glycosyl transferase family 2 YP_003918396.1 3607015 R 861360 CDS YP_003918397.1 308178991 9796806 complement(3608376..3609296) 1 NC_014550.1 hypothetical protein 3609296 9796806 AARI_32270 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918397.1 3608376 R 861360 CDS YP_003918398.1 308178992 9796807 complement(3609296..3610210) 1 NC_014550.1 LmbE-like protein 3610210 9796807 AARI_32280 Arthrobacter arilaitensis Re117 LmbE-like protein YP_003918398.1 3609296 R 861360 CDS YP_003918399.1 308178993 9793555 complement(3611989..3613296) 1 NC_014550.1 transposase of ISAar19, ISL3 family 3613296 9793555 AARI_36180 Arthrobacter arilaitensis Re117 transposase of ISAar19, ISL3 family YP_003918399.1 3611989 R 861360 CDS YP_003918400.1 308178994 9793556 complement(3613522..3618252) 1 NC_014550.1 2 transmembrane helices predicted by TMHMM2.0; hypothetical protein 3618252 9793556 AARI_32290 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918400.1 3613522 R 861360 CDS YP_003918401.1 308178995 9796809 complement(3618739..3619914) 1 NC_014550.1 match to PF00196: bacterial regulatory proteins, luxR family. This domain is a DNA-binding, helix-turn- helix (HTH) domain of about 65 amino acids, present in transcription regulators of the LuxR/FixJ family of response regulators; hypothetical protein 3619914 9796809 AARI_32300 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918401.1 3618739 R 861360 CDS YP_003918402.1 308178996 9796810 complement(3620020..3621045) 1 NC_014550.1 hypothetical protein 3621045 9796810 AARI_32310 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918402.1 3620020 R 861360 CDS YP_003918403.1 308178997 9796811 complement(3621165..3621479) 1 NC_014550.1 1 transmembrane helice predicted by TMHMM2.0; hypothetical protein 3621479 9796811 AARI_32320 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918403.1 3621165 R 861360 CDS YP_003918404.1 308178998 9796812 complement(3621738..3623120) 1 NC_014550.1 hydrolyzes allantoin into allantoate. Involved in purine degradation; allantoinase 3623120 allB 9796812 allB Arthrobacter arilaitensis Re117 allantoinase YP_003918404.1 3621738 R 861360 CDS YP_003918405.1 308178999 9793663 complement(3623272..3625065) 1 NC_014550.1 catalyses the following reaction: 2 glyoxylate <=> tartronate semialdehyde + CO(2); tartronate-semialdehyde synthase 3625065 gcl 9793663 gcl Arthrobacter arilaitensis Re117 tartronate-semialdehyde synthase YP_003918405.1 3623272 R 861360 CDS YP_003918406.1 308179000 9793890 3625128..3625319 1 NC_014550.1 hypothetical protein 3625319 9793890 AARI_32350 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918406.1 3625128 D 861360 CDS YP_003918407.1 308179001 9796813 complement(3625335..3626234) 1 NC_014550.1 catalyses the following reaction: (R)-glycerate + NAD(P)(+) <=> 2-hydroxy-3-oxopropanoate + NAD(P)H; 2-hydroxy-3-oxopropionate reductase 3626234 9796813 AARI_32360 Arthrobacter arilaitensis Re117 2-hydroxy-3-oxopropionate reductase YP_003918407.1 3625335 R 861360 CDS YP_003918408.1 308179002 9796814 complement(3626268..3627059) 1 NC_014550.1 catalyses the following reaction: hydroxypyruvate <=> 2-hydroxy-3-oxopropanoate; hydroxypyruvate isomerase 3627059 9796814 AARI_32370 Arthrobacter arilaitensis Re117 hydroxypyruvate isomerase YP_003918408.1 3626268 R 861360 CDS YP_003918409.1 308179003 9796815 3627811..3629223 1 NC_014550.1 Nucleobase:Cation Symporter-1 (NCS1) Family (TC 2.A. 39.y.z); hydantoin/allantoin permease 3629223 9796815 AARI_32380 Arthrobacter arilaitensis Re117 hydantoin/allantoin permease YP_003918409.1 3627811 D 861360 CDS YP_003918410.1 308179004 9796816 3629233..3629979 1 NC_014550.1 identified by similarity to protein SP:Q00924 (Pseudomonas sp. strain NS671). Match to protein family PF01177: Asp/Glu/Hydantoin racemase. Hydantoin racemase is responsible for racemization of the D-5-substituted hydantoins to their corresponding L-amino acids; hydantoin racemase 3629979 hyuE 9796816 hyuE Arthrobacter arilaitensis Re117 hydantoin racemase YP_003918410.1 3629233 D 861360 CDS YP_003918411.1 308179005 9793995 complement(3630309..3630839) 1 NC_014550.1 hypothetical protein 3630839 9793995 AARI_32400 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918411.1 3630309 R 861360 CDS YP_003918412.1 308179006 9796817 complement(3630883..3631194) 1 NC_014550.1 hypothetical protein 3631194 9796817 AARI_32410 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918412.1 3630883 R 861360 CDS YP_003918413.1 308179007 9796818 complement(3631898..3632584) 1 NC_014550.1 hypothetical protein 3632584 9796818 AARI_32420 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918413.1 3631898 R 861360 CDS YP_003918414.1 308179008 9796819 3632761..3632982 1 NC_014550.1 hypothetical protein 3632982 9796819 AARI_32430 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918414.1 3632761 D 861360 CDS YP_003918415.1 308179009 9796820 3632992..3633519 1 NC_014550.1 hypothetical protein 3633519 9796820 AARI_32440 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918415.1 3632992 D 861360 CDS YP_003918416.1 308179010 9796821 3633813..3634799 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, iron chelate uptake transporter (FeCT) family (TC 3.A.1.14.z). ABCISSE: ABC transporter, binding protein (BP), ISVH- family (iron siderophores, vitamin B12 and hemin); iron-siderophore ABC transporter substrate-binding protein 3634799 9796821 AARI_32450 Arthrobacter arilaitensis Re117 iron-siderophore ABC transporter substrate-binding protein YP_003918416.1 3633813 D 861360 CDS YP_003918417.1 308179011 9796822 3634900..3635871 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, iron chelate uptake transporter (FeCT) family (TC 3.A.1.14.z). ABCISSE: ABC transporter, permease (IM), ISVH-family (iron siderophores, vitamin B12 and hemin); iron-siderophore ABC transporter inner membrane subunit 3635871 9796822 AARI_32460 Arthrobacter arilaitensis Re117 iron-siderophore ABC transporter inner membrane subunit YP_003918417.1 3634900 D 861360 CDS YP_003918418.1 308179012 9796823 3635876..3636910 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, iron chelate uptake transporter (FeCT) family (TC 3.A.1.14.z). ABCISSE: ABC transporter, permease (IM), ISVH-family (iron siderophores, vitamin B12 and hemin); iron-siderophore ABC transporter inner membrane subunit 3636910 9796823 AARI_32470 Arthrobacter arilaitensis Re117 iron-siderophore ABC transporter inner membrane subunit YP_003918418.1 3635876 D 861360 CDS YP_003918419.1 308179013 9796824 3636907..3637662 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, iron chelate uptake transporter (FeCT) family (TC 3.A.1.14.z). ABCISSE: ABC transporter, ATP-binding protein (ABC), ISVH- family (iron siderophores, vitamin B12 and hemin); iron-siderophore ABC transporter ATP-binding subunit 3637662 9796824 AARI_32480 Arthrobacter arilaitensis Re117 iron-siderophore ABC transporter ATP-binding subunit YP_003918419.1 3636907 D 861360 CDS YP_003918420.1 308179014 9796825 3637712..3638113 1 NC_014550.1 hypothetical protein 3638113 9796825 AARI_32490 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918420.1 3637712 D 861360 CDS YP_003918421.1 308179015 9796826 complement(3638110..3639381) 1 NC_014550.1 match to protein family PF07690: Major Facilitator Superfamily; permease 3639381 9796826 AARI_32500 Arthrobacter arilaitensis Re117 permease YP_003918421.1 3638110 R 861360 CDS YP_003918422.1 308179016 9796827 complement(3639745..3640527) 1 NC_014550.1 carbonate dehydratases are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide. They are ubiquitous enzymes involved in fundamental processes like respiration, pH homeostasis and ion transport. Signal peptide predicted by SignalP 3.0 HMM (probability: 0.975) with cleavage site probability 0.621 between position 42 and 43; carbonate dehydratase 3640527 9796827 AARI_32510 Arthrobacter arilaitensis Re117 carbonate dehydratase YP_003918422.1 3639745 R 861360 CDS YP_003918423.1 308179017 9796828 3640799..3641434 1 NC_014550.1 identified by match to PF00440: bacterial regulatory proteins, tetR family; TetR family transcriptional regulator 3641434 9796828 AARI_32520 Arthrobacter arilaitensis Re117 TetR family transcriptional regulator YP_003918423.1 3640799 D 861360 CDS YP_003918424.1 308179018 9796829 3641439..3643043 1 NC_014550.1 enzymes named acetyl-coenzyme A carboxylase (EC 6.4. 1.2), propionyl-coenzyme A carboxylase (EC 6.4.1.3) and acyl-coenzyme A carboxylase are constituted by several types of subunits. Alpha subunits contains the biotin carboxylase (BC, EC 6.3.4.14) and biotin carboxyl carrier protein (BCCP) domains, beta subunits contain the carboxyltransferase (CT) domain. An epsilon subunit is present in some microorganisms; acetyl-/propionyl-coenzyme A carboxylase subunit beta 3643043 9796829 AARI_32530 Arthrobacter arilaitensis Re117 acetyl-/propionyl-coenzyme A carboxylase subunit beta YP_003918424.1 3641439 D 861360 CDS YP_003918425.1 308179019 9796830 3643056..3645116 1 NC_014550.1 enzymes named acetyl-coenzyme A carboxylase (EC 6.4. 1.2), propionyl-coenzyme A carboxylase (EC 6.4.1.3) and acyl-coenzyme A carboxylase are constituted by several types of subunits. Alpha subunits contains the biotin carboxylase (BC, EC 6.3.4.14) and biotin carboxyl carrier protein (BCCP) domains, beta subunits contain the carboxyltransferase (CT) domain. An epsilon subunit is present in some microorganisms; acetyl-/propionyl-coenzyme A carboxylase subunit alpha 3645116 accA 9796830 accA Arthrobacter arilaitensis Re117 acetyl-/propionyl-coenzyme A carboxylase subunit alpha YP_003918425.1 3643056 D 861360 CDS YP_003918426.1 308179020 9793646 3645113..3645637 1 NC_014550.1 match to PF01575. Several bacterial proteins that are composed solely of this domain have (R)-specific enoyl- CoA hydratase activity; MaoC like domain-containing protein 3645637 9793646 AARI_32550 Arthrobacter arilaitensis Re117 MaoC like domain-containing protein YP_003918426.1 3645113 D 861360 CDS YP_003918427.1 308179021 9796831 3645645..3646430 1 NC_014550.1 citrate lyase catalyses the formation of acetate and oxaloacetate from citrate; citrate lyase beta subunit 3646430 9796831 AARI_32560 Arthrobacter arilaitensis Re117 citrate lyase beta subunit YP_003918427.1 3645645 D 861360 CDS YP_003918428.1 308179022 9796832 3646497..3647000 1 NC_014550.1 2 transmembrane helices predicted by TMHMM2.0; hypothetical protein 3647000 9796832 AARI_32570 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918428.1 3646497 D 861360 CDS YP_003918429.1 308179023 9796834 3648498..3648782 1 NC_014550.1 transcriptional regulator 3648782 9796834 AARI_32590 Arthrobacter arilaitensis Re117 transcriptional regulator YP_003918429.1 3648498 D 861360 CDS YP_003918430.1 308179024 9796835 complement(3648821..3649189) 1 NC_014550.1 2 transmembrane helices predicted by TMHMM2.0; hypothetical protein 3649189 9796835 AARI_32600 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918430.1 3648821 R 861360 CDS YP_003918431.1 308179025 9796837 3649839..3651140 1 NC_014550.1 major facilitator superfamily (TC 2.A.1.y.z). Identified by match to protein family PF07690; MFS superfamily transporter 3651140 9796837 AARI_32620 Arthrobacter arilaitensis Re117 MFS superfamily transporter YP_003918431.1 3649839 D 861360 CDS YP_003918432.1 308179026 9796838 complement(3651234..3651671) 1 NC_014550.1 4 transmembrane helices predicted by TMHMM2.0; hypothetical protein 3651671 9796838 AARI_32630 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918432.1 3651234 R 861360 CDS YP_003918433.1 308179027 9796920 complement(3652785..3653015) 1 NC_014550.1 hypothetical protein 3653015 9796920 AARI_32640 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918433.1 3652785 R 861360 CDS YP_003918434.1 308179028 9793557 complement(3653726..3655033) 1 NC_014550.1 transposase of ISAar20, ISL3 family 3655033 9793557 AARI_36200 Arthrobacter arilaitensis Re117 transposase of ISAar20, ISL3 family YP_003918434.1 3653726 R 861360 CDS YP_003918435.1 308179029 9793558 3656139..3656399 1 NC_014550.1 2 transmembrane helices predicted by TMHMM2.0; hypothetical protein 3656399 9793558 AARI_32650 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918435.1 3656139 D 861360 CDS YP_003918436.1 308179030 9796922 complement(3656660..3658105) 1 NC_014550.1 transposase of ISAar22, IS481 family 3658105 9796922 AARI_36210 Arthrobacter arilaitensis Re117 transposase of ISAar22, IS481 family YP_003918436.1 3656660 R 861360 CDS YP_003918437.1 308179031 9793559 complement(3658625..3659080) 1 NC_014550.1 4 transmembrane helices predicted by TMHMM2.0; hypothetical protein 3659080 9793559 AARI_32660 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918437.1 3658625 R 861360 CDS YP_003918438.1 308179032 9796923 complement(3659202..3659531) 1 NC_014550.1 3 transmembrane helices predicted by TMHMM2.0; hypothetical protein 3659531 9796923 AARI_32670 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918438.1 3659202 R 861360 CDS YP_003918439.1 308179033 9796924 complement(3659531..3659914) 1 NC_014550.1 3 transmembrane helices predicted by TMHMM2.0; hypothetical protein 3659914 9796924 AARI_32680 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918439.1 3659531 R 861360 CDS YP_003918440.1 308179034 9796925 3660064..3661110 1 NC_014550.1 identified by match to PF00753: metallo-beta- lactamase superfamily. Apart from the beta-lactamases, a number of other proteins contain this domain. These proteins include thiolesterases, members of the glyoxalase II family, that catalyse the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid and a competence protein that is essential for natural transformation in Neisseria gonorrhoeae and could be a transporter involved in DNA uptake; metallo-beta-lactamase 3661110 9796925 AARI_32690 Arthrobacter arilaitensis Re117 metallo-beta-lactamase YP_003918440.1 3660064 D 861360 CDS YP_003918441.1 308179035 9796928 complement(3662491..3663417) 1 NC_014550.1 identified by match to PF00126: bacterial regulatory helix-turn-helix protein, lysR family. Numerous bacterial transcription regulatory proteins bind DNA via a helix-turn-helix (HTH) motif. These proteins are very diverse, but for convenience may be grouped into subfamilies on the basis of sequence similarity. One such family, the lysR family, groups together a range of proteins, including ampR, catM, catR, cynR, cysB, gltC, iciA, ilvY, irgB, lysR, metR, mkaC, mleR, nahR, nhaR, nodD, nolR, oxyR, pssR, rbcR, syrM, tcbR, tfdS and trpI. The majority of these proteins appear to be transcription activators and most are known to negatively regulate their own expression. All possess a potential HTH DNA-binding motif towards their N-termini; LysR family transcriptional regulator 3663417 9796928 AARI_32720 Arthrobacter arilaitensis Re117 LysR family transcriptional regulator YP_003918441.1 3662491 R 861360 CDS YP_003918442.1 308179036 9796929 complement(3663449..3663736) 1 NC_014550.1 hypothetical protein 3663736 9796929 AARI_32730 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918442.1 3663449 R 861360 CDS YP_003918443.1 308179037 9796930 complement(3663843..3665072) 1 NC_014550.1 possibly involved in the metabolism of lipids. Match to PF08028. Acyl-CoA dehydrogenases catalyze the alpha,beta-dehydrogenation of acyl-CoA thioesters to the corresponding trans 2,3-enoyl CoA-products with concommitant reduction of enzyme-bound FAD; acyl-CoA dehydrogenase 3665072 9796930 AARI_32740 Arthrobacter arilaitensis Re117 acyl-CoA dehydrogenase YP_003918443.1 3663843 R 861360 CDS YP_003918444.1 308179038 9796931 complement(3665101..3666312) 1 NC_014550.1 possibly involved in the metabolism of lipids. Match to PF08028, PF02770 and PF02771. Acyl-CoA dehydrogenases catalyze the alpha,beta-dehydrogenation of acyl-CoA thioesters to the corresponding trans 2,3-enoyl CoA-products with concommitant reduction of enzyme-bound FAD; acyl-CoA dehydrogenase 3666312 9796931 AARI_32750 Arthrobacter arilaitensis Re117 acyl-CoA dehydrogenase YP_003918444.1 3665101 R 861360 CDS YP_003918445.1 308179039 9796932 complement(3666579..3667631) 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, iron chelate uptake transporter (FeCT) family (TC 3.A.1.14.z). ABCISSE: ABC transporter, permease (IM), ISVH-family (iron siderophores, vitamin B12 and hemin); iron-siderophore ABC transporter inner membrane subunit 3667631 9796932 AARI_32760 Arthrobacter arilaitensis Re117 iron-siderophore ABC transporter inner membrane subunit YP_003918445.1 3666579 R 861360 CDS YP_003918446.1 308179040 9796933 complement(3667618..3668667) 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, iron chelate uptake transporter (FeCT) family (TC 3.A.1.14.z). ABCISSE: ABC transporter, permease (IM), ISVH-family (iron siderophores, vitamin B12 and hemin); iron-siderophore ABC transporter inner membrane subunit 3668667 9796933 AARI_32770 Arthrobacter arilaitensis Re117 iron-siderophore ABC transporter inner membrane subunit YP_003918446.1 3667618 R 861360 CDS YP_003918447.1 308179041 9796934 complement(3668669..3669523) 1 NC_014550.1 identified by match to protein family PF04954. Match to protein domain PF08021. Possibly involved in removal of iron from iron-siderophore complexes; siderophore-interacting protein 3669523 9796934 AARI_32780 Arthrobacter arilaitensis Re117 siderophore-interacting protein YP_003918447.1 3668669 R 861360 CDS YP_003918448.1 308179042 9796935 complement(3669548..3670552) 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, iron chelate uptake transporter (FeCT) family (TC 3.A.1.14.z). ABCISSE: ABC transporter, binding protein (BP), ISVH- family (iron siderophores, vitamin B12 and hemin); iron-siderophore ABC transporter substrate-binding protein 3670552 9796935 AARI_32790 Arthrobacter arilaitensis Re117 iron-siderophore ABC transporter substrate-binding protein YP_003918448.1 3669548 R 861360 CDS YP_003918449.1 308179043 9796936 3670735..3671505 1 NC_014550.1 identified by match to PF01648: 4- phosphopantetheinyl transferase superfamily. Holo-[acyl- carrier-protein] synthase catalyses the following reaction: CoA-(4-phosphopantetheine) + apo-[acyl-carrier- protein] => adenosine 3,5-bisphosphate + holo-[acyl- carrier-protein]. All polyketide synthases, fatty-acid synthases and non-ribosomal peptide synthases require post- translational modification of their constituent acyl- carrier-protein (ACP) domains to become catalytically active. The inactive apo-proteins are converted into their active holo-forms by transfer of the 4-phosphopantetheinyl moiety of CoA to the sidechain hydroxy group of a conserved serine residue in each ACP domain; non-ribosomal peptide synthase accessory protein 3671505 9796936 AARI_32800 Arthrobacter arilaitensis Re117 non-ribosomal peptide synthase accessory protein YP_003918449.1 3670735 D 861360 CDS YP_003918450.1 308179044 9796937 complement(3671528..3672880) 1 NC_014550.1 Major Facilitator Superfamily (MFS), Enterobactin (Siderophore) Exporter (EntS) Family (TC 2.A.1.38.z); siderophore exporter 3672880 9796937 AARI_32810 Arthrobacter arilaitensis Re117 siderophore exporter YP_003918450.1 3671528 R 861360 CDS YP_003918451.1 308179045 9796938 complement(3672877..3673071) 1 NC_014550.1 identified by match to protein domain PF03621. This domain is found in the MbtH protein O05821 (probably involved in mycobactin synthesis) as well as at the N terminus of the antibiotic synthesis protein NIKP1. Many of the members of this family are found in known antibiotic synthesis gene clusters. Possible involvement in the synthesis of siderophore group non-ribosomal peptides; MbtH-like protein 3673071 9796938 AARI_32820 Arthrobacter arilaitensis Re117 MbtH-like protein YP_003918451.1 3672877 R 861360 CDS YP_003918452.1 308179046 9796939 complement(3673121..3677149) 1 NC_014550.1 non-ribosomal siderophore peptide synthetase component 3677149 9796939 AARI_32830 Arthrobacter arilaitensis Re117 non-ribosomal siderophore peptide synthetase component YP_003918452.1 3673121 R 861360 CDS YP_003918453.1 308179047 9796940 complement(3677149..3683670) 1 NC_014550.1 non-ribosomal siderophore peptide synthetase component 3683670 9796940 AARI_32840 Arthrobacter arilaitensis Re117 non-ribosomal siderophore peptide synthetase component YP_003918453.1 3677149 R 861360 CDS YP_003918454.1 308179048 9796941 complement(3683770..3685194) 1 NC_014550.1 non-ribosomal siderophore peptide synthetase component 3685194 9796941 AARI_32850 Arthrobacter arilaitensis Re117 non-ribosomal siderophore peptide synthetase component YP_003918454.1 3683770 R 861360 CDS YP_003918455.1 308179049 9796942 complement(3685277..3688540) 1 NC_014550.1 non-ribosomal siderophore peptide synthetase component 3688540 9796942 AARI_32860 Arthrobacter arilaitensis Re117 non-ribosomal siderophore peptide synthetase component YP_003918455.1 3685277 R 861360 CDS YP_003918456.1 308179050 9796943 complement(3688579..3688824) 1 NC_014550.1 non-ribosomal siderophore peptide synthetase component 3688824 9796943 AARI_32870 Arthrobacter arilaitensis Re117 non-ribosomal siderophore peptide synthetase component YP_003918456.1 3688579 R 861360 CDS YP_003918457.1 308179051 9796944 complement(3688821..3690161) 1 NC_014550.1 L-ornithine 5-monooxygenase catalyzes the conversion of L-ornithine into N5-hydroxy-L-ornithine, which is later incorporated in the siderophore pyoverdin, produced by Pseudomonas aeruginosa; L-ornithine 5-monooxygenase 3690161 9796944 AARI_32880 Arthrobacter arilaitensis Re117 L-ornithine 5-monooxygenase YP_003918457.1 3688821 R 861360 CDS YP_003918458.1 308179052 9796945 complement(3690158..3691807) 1 NC_014550.1 similar to enterobactin synthase subunit E, which includes (2,3-dihydroxybenzoyl)adenylate synthase activity (EC 2.7.7.58); non-ribosomal siderophore peptide synthetase component 3691807 9796945 AARI_32890 Arthrobacter arilaitensis Re117 non-ribosomal siderophore peptide synthetase component YP_003918458.1 3690158 R 861360 CDS YP_003918459.1 308179053 9796946 complement(3691804..3692985) 1 NC_014550.1 plays a role in the siderophore biosynthesis and in the bacillibactin biosynthesis; isochorismate synthase 3692985 dhbC 9796946 dhbC Arthrobacter arilaitensis Re117 isochorismate synthase YP_003918459.1 3691804 R 861360 CDS YP_003918460.1 308179054 9793813 complement(3693038..3693796) 1 NC_014550.1 involved in the third stage of enterobactin (siderophore peptide) biosynthesis, the conversion of 2,3- dihydro-2,3-dihydroxybenzoate into 2,3-dihydroxybenzoate; 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase 3693796 dhbA 9793813 dhbA Arthrobacter arilaitensis Re117 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase YP_003918460.1 3693038 R 861360 CDS YP_003918461.1 308179055 9793811 complement(3693793..3694449) 1 NC_014550.1 involved in the second stage of enterobactin (siderophore peptide) biosynthesis, the conversion of isochorismate into 2,3-dihydroxy-2,3-dihydrobenzoate; isochorismatase 3694449 dhbB 9793811 dhbB Arthrobacter arilaitensis Re117 isochorismatase YP_003918461.1 3693793 R 861360 CDS YP_003918462.1 308179056 9793812 3695142..3696065 1 NC_014550.1 signal peptide predicted by SignalP 3.0 HMM (probability: 1.000) with cleavage site probability 0.995 between position 30 and 31; hypothetical protein 3696065 9793812 AARI_32930 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918462.1 3695142 D 861360 CDS YP_003918463.1 308179057 9796948 complement(3696394..3697227) 1 NC_014550.1 identified by similarity to protein SP:O31168 (Streptomyces aureofaciens). Catalyzes the following reaction: 2 RH + 2 Cl(-) + H(2)O(2) <=> 2 RCl + 2 H(2)O. Brings about the chlorination of a range of organic molecules, forming stable C-Cl bonds; chloride peroxidase 3697227 9796948 AARI_32950 Arthrobacter arilaitensis Re117 chloride peroxidase YP_003918463.1 3696394 R 861360 CDS YP_003918464.1 308179058 9796949 complement(3697336..3697611) 1 NC_014550.1 hypothetical protein 3697611 9796949 AARI_32960 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918464.1 3697336 R 861360 CDS YP_003918465.1 308179059 9796950 complement(3697615..3698976) 1 NC_014550.1 Gluconate:H+ Symporter (GntP) Family (TC 2.A.8.y.z). Match to protein family PF02447; gluconate permease 3698976 9796950 AARI_32970 Arthrobacter arilaitensis Re117 gluconate permease YP_003918465.1 3697615 R 861360 CDS YP_003918466.1 308179060 9796951 complement(3699269..3700330) 1 NC_014550.1 match to protein domain PF05651: sugar diacid recognition; hypothetical protein 3700330 9796951 AARI_32980 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918466.1 3699269 R 861360 CDS YP_003918467.1 308179061 9796952 3700457..3700639 1 NC_014550.1 hypothetical protein 3700639 9796952 AARI_32990 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918467.1 3700457 D 861360 CDS YP_003918468.1 308179062 9796953 complement(3700726..3701274) 1 NC_014550.1 signal peptide predicted by SignalP 3.0 HMM (probability: 0.994) with cleavage site probability 0.846 between position 30 and 31; hypothetical protein 3701274 9796953 AARI_33000 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918468.1 3700726 R 861360 CDS YP_003918469.1 308179063 9796956 complement(3702230..3703408) 1 NC_014550.1 catalyses the following reaction: ATP + (R)- glycerate <=> ADP + 3-phospho-(R)-glycerate; glycerate kinase 3703408 glxK 9796956 glxK Arthrobacter arilaitensis Re117 glycerate kinase YP_003918469.1 3702230 R 861360 CDS YP_003918470.1 308179064 9793925 3704444..3704914 1 NC_014550.1 hypothetical protein 3704914 9793925 AARI_33040 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918470.1 3704444 D 861360 CDS YP_003918471.1 308179065 9796957 3705074..3706564 1 NC_014550.1 Sulfate Permease (SulP) Family, sulfate permease (TC 2.A.53.3.1); sulfate permease 3706564 9796957 AARI_33050 Arthrobacter arilaitensis Re117 sulfate permease YP_003918471.1 3705074 D 861360 CDS YP_003918472.1 308179066 9796958 complement(3706570..3707529) 1 NC_014550.1 transposase of ISAar35, IS481 family 3707529 9796958 AARI_36220 Arthrobacter arilaitensis Re117 transposase of ISAar35, IS481 family YP_003918472.1 3706570 R 861360 CDS YP_003918473.1 308179067 9793560 complement(3707672..3709279) 1 NC_014550.1 activates fatty acids by binding to coenzyme A. Possibly involved in the synthesis of cellular lipids or their degradation via beta-oxidation; fatty-acid--CoA ligase 3709279 9793560 AARI_33060 Arthrobacter arilaitensis Re117 fatty-acid--CoA ligase YP_003918473.1 3707672 R 861360 CDS YP_003918474.1 308179068 9796959 3709660..3710586 1 NC_014550.1 possibly involved in the regulation of the catechol catabolism.Match to PF00126: bacterial regulatory helix- turn-helix protein, lysR family; transcriptional regulator CatR 3710586 catR 9796959 catR Arthrobacter arilaitensis Re117 transcriptional regulator CatR YP_003918474.1 3709660 D 861360 CDS YP_003918475.1 308179069 9793731 3710567..3711688 1 NC_014550.1 identified by similarity to protein SP:Q76CC6 (Arthrobacter sp.). Involved in the degradation of aromatic compounds by converting cis,cis-muconate, the product of catechol ring cleavage to (4S)-muconolactone; muconate cycloisomerase 3711688 catB 9793731 catB Arthrobacter arilaitensis Re117 muconate cycloisomerase YP_003918475.1 3710567 D 861360 CDS YP_003918476.1 308179070 9793729 3711701..3711979 1 NC_014550.1 catalyses the third step in the catabolism of catechol to succinyl-CoA and acetyl-CoA in the beta- ketoadipate pathway; muconolactone Delta-isomerase 3711979 catC 9793729 catC Arthrobacter arilaitensis Re117 muconolactone Delta-isomerase YP_003918476.1 3711701 D 861360 CDS YP_003918477.1 308179071 9793730 3712173..3713030 1 NC_014550.1 catalyses the third step in the catabolism of catechol to succinyl-CoA and acetyl-CoA in the beta- ketoadipate pathway: the intradiol cleavage reaction of catechol to form cis,cis-muconate; catechol 1,2-dioxygenase 3713030 catA 9793730 catA Arthrobacter arilaitensis Re117 catechol 1,2-dioxygenase YP_003918477.1 3712173 D 861360 CDS YP_003918478.1 308179072 9793728 3713134..3713634 1 NC_014550.1 signal peptide predicted by SignalP 3.0 HMM (probability: 0.966) with cleavage site probability 0.717 between position 31 and 32. 3 transmembrane helices predicted by TMHMM2.0 after the signal peptide; hypothetical protein 3713634 9793728 AARI_33110 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918478.1 3713134 D 861360 CDS YP_003918479.1 308179073 9796960 3713779..3715338 1 NC_014550.1 identified by match to cd00085: HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins; HNH endonuclease domain-containing protein 3715338 9796960 AARI_33120 Arthrobacter arilaitensis Re117 HNH endonuclease domain-containing protein YP_003918479.1 3713779 D 861360 CDS YP_003918480.1 308179074 9796964 3716847..3718265 1 NC_014550.1 major facilitator superfamily (MFS), drug:H+ antiporter-3 (12 spanner) (DHA3) family, multidrug (erythromycin, tetracycline, puromycin, bleomycin) resistance protein Cmr (TC 2.A.1.21.2). Identified by similarity to protein SP:Q79VC7 (Corynebacterium glutamicum). Probable drug antiporter which uses the proton motive force for the active efflux drugs; multidrug resistance protein 3718265 cmr 9796964 cmr Arthrobacter arilaitensis Re117 multidrug resistance protein YP_003918480.1 3716847 D 861360 CDS YP_003918481.1 308179075 9796965 complement(3718684..3719094) 1 NC_014550.1 signal peptide predicted by SignalP 3.0 HMM (probability: 0.976) with cleavage site probability 0.942 between position 24 and 25. 3 transmembrane helices predicted by TMHMM2.0 after the signal peptide; hypothetical protein 3719094 9796965 AARI_33180 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918481.1 3718684 R 861360 CDS YP_003918482.1 308179076 9796966 complement(3719207..3720316) 1 NC_014550.1 hypothetical protein 3720316 9796966 AARI_33190 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918482.1 3719207 R 861360 CDS YP_003918483.1 308179077 9796967 3720720..3721496 1 NC_014550.1 electron transfer flavoproteins (ETFs) serve as specific electron acceptors for primary dehydrogenases, transferring the electrons to terminal respiratory systems. They can be functionally classified into constitutive, (housekeeping) ETFs, mainly involved in the oxidation of fatty acids (Group I), and ETFs produced by some prokaryotes under specific growth conditions, receiving electrons only from the oxidation of specific substrates (Group II). They consist of three domains: domains I and II are formed by the N- and C-terminal portions of the alpha subunit, respectively, while domain III is formed by the beta subunit; electron transfer flavoprotein subunit beta 3721496 fixA 9796967 fixA Arthrobacter arilaitensis Re117 electron transfer flavoprotein subunit beta YP_003918483.1 3720720 D 861360 CDS YP_003918484.1 308179078 9793852 3721493..3722491 1 NC_014550.1 electron transfer flavoproteins (ETFs) serve as specific electron acceptors for primary dehydrogenases, transferring the electrons to terminal respiratory systems. They can be functionally classified into constitutive, (housekeeping) ETFs, mainly involved in the oxidation of fatty acids (Group I), and ETFs produced by some prokaryotes under specific growth conditions, receiving electrons only from the oxidation of specific substrates (Group II). They consist of three domains: domains I and II are formed by the N- and C-terminal portions of the alpha subunit, respectively, while domain III is formed by the beta subunit; electron transfer flavoprotein subunit alpha 3722491 fixB 9793852 fixB Arthrobacter arilaitensis Re117 electron transfer flavoprotein subunit alpha YP_003918484.1 3721493 D 861360 CDS YP_003918485.1 308179079 9793854 3722497..3724410 1 NC_014550.1 6 transmembrane helices predicted by TMHMM2.0; hypothetical protein 3724410 9793854 AARI_33220 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918485.1 3722497 D 861360 CDS YP_003918486.1 308179080 9796968 3724513..3725181 1 NC_014550.1 identified by match to protein domain PF08241; SAM-dependent methyltransferase 3725181 9796968 AARI_33230 Arthrobacter arilaitensis Re117 SAM-dependent methyltransferase YP_003918486.1 3724513 D 861360 CDS YP_003918487.1 308179081 9796970 complement(3725558..3727348) 1 NC_014550.1 hypothetical protein 3727348 9796970 AARI_33250 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918487.1 3725558 R 861360 CDS YP_003918488.1 308179082 9796971 3727565..3728188 1 NC_014550.1 hypothetical protein 3728188 9796971 AARI_33260 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918488.1 3727565 D 861360 CDS YP_003918489.1 308179083 9796972 3728279..3728977 1 NC_014550.1 hypothetical protein 3728977 9796972 AARI_33270 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918489.1 3728279 D 861360 CDS YP_003918490.1 308179084 9796973 3729072..3730121 1 NC_014550.1 match to PF02492 (CobW/HypB/UreG, nucleotide- binding domain) and PF07683 (Cobalamin synthesis protein cobW C-terminal domain). In Pseudomonas denitrificans, the cobW gene product may be involved in cobalamin biosynthesis; cobalamin biosynthesis protein 3730121 9796973 AARI_33280 Arthrobacter arilaitensis Re117 cobalamin biosynthesis protein YP_003918490.1 3729072 D 861360 CDS YP_003918491.1 308179085 9796974 complement(3730150..3730341) 1 NC_014550.1 2 transmembrane helices predicted by TMHMM2.0; hypothetical protein 3730341 9796974 AARI_33290 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918491.1 3730150 R 861360 CDS YP_003918492.1 308179086 9796975 3730937..3732016 1 NC_014550.1 transposase of ISAar29, IS110 family 3732016 9796975 AARI_36230 Arthrobacter arilaitensis Re117 transposase of ISAar29, IS110 family YP_003918492.1 3730937 D 861360 CDS YP_003918493.1 308179087 9793561 complement(3732631..3733932) 1 NC_014550.1 transposase of ISAar34, ISL3 family 3733932 9793561 AARI_36240 Arthrobacter arilaitensis Re117 transposase of ISAar34, ISL3 family YP_003918493.1 3732631 R 861360 CDS YP_003918494.1 308179088 9793562 complement(3734102..3737563) 1 NC_014550.1 type I restriction endonucleases are components of prokaryotic DNA restriction-modification mechanisms that protects the organism against invading foreign DNA. They have three different subunits: subunits - M (modification), S (specificity) and R (restriction) - that form multifunctional enzymes with restriction (EC:3.1.21.3), methylase (EC:2.1.1.72) and ATPase activities. The S subunit is required for both restriction and modification and is responsible for recognition of the DNA sequence specific for the system. The M subunit is necessary for modification, and the R subunit is required for restriction. They recognize asymmetric DNA sequences split into two domains of specific sequence, one 3-4 bp long and another 4-5 bp long, separated by a nonspecific spacer 6-8 bp in length. Cleavage occurs a considerable distance from the recognition sites, rarely less than 400 bp away and up to 7000 bp away. Adenosyl residues are methylated, one on each strand of the recognition sequence; type I restriction-modification system restriction subunit 3737563 hsdR 9793562 hsdR Arthrobacter arilaitensis Re117 type I restriction-modification system restriction subunit YP_003918494.1 3734102 R 861360 CDS YP_003918495.1 308179089 9793982 complement(3738097..3739311) 1 NC_014550.1 identified by match to PF02661: Fic protein family. cAMP may be a regulation factor in cell division of some bacteria. The Fic (filamentation induced by cAMP) protein is involved in the synthesis of PAB or folate. It would appear that the Fic protein and cAMP are involved in a regulatory mechanism of cell division via folate metabolism and in these organisms cell division could be controlled by coordination of cAMP, Fic and Fts proteins; Fic family protein 3739311 9793982 AARI_33310 Arthrobacter arilaitensis Re117 Fic family protein YP_003918495.1 3738097 R 861360 CDS YP_003918496.1 308179090 9796976 complement(3739594..3740523) 1 NC_014550.1 identified by match to PF04471. Mrr is involved in the acceptance of foreign DNA which is modified. Restricts both adenine- and cytosine-methylated DNA; restriction system protein Mrr 3740523 mrr 9796976 mrr Arthrobacter arilaitensis Re117 restriction system protein Mrr YP_003918496.1 3739594 R 861360 CDS YP_003918497.1 308179091 9794108 complement(3740523..3741704) 1 NC_014550.1 type I restriction endonucleases are components of prokaryotic DNA restriction-modification mechanisms that protects the organism against invading foreign DNA. They have three different subunits: subunits - M (modification), S (specificity) and R (restriction) - that form multifunctional enzymes with restriction (EC:3.1.21.3), methylase (EC:2.1.1.72) and ATPase activities. The S subunit is required for both restriction and modification and is responsible for recognition of the DNA sequence specific for the system. The M subunit is necessary for modification, and the R subunit is required for restriction. They recognize asymmetric DNA sequences split into two domains of specific sequence, one 3-4 bp long and another 4-5 bp long, separated by a nonspecific spacer 6-8 bp in length. Cleavage occurs a considerable distance from the recognition sites, rarely less than 400 bp away and up to 7000 bp away. Adenosyl residues are methylated, one on each strand of the recognition sequence; type I restriction-modification system specificity subunit 3741704 hsdS 9794108 hsdS Arthrobacter arilaitensis Re117 type I restriction-modification system specificity subunit YP_003918497.1 3740523 R 861360 CDS YP_003918498.1 308179092 9793985 complement(3741701..3743221) 1 NC_014550.1 type I restriction endonucleases are components of prokaryotic DNA restriction-modification mechanisms that protects the organism against invading foreign DNA. They have three different subunits: subunits - M (modification), S (specificity) and R (restriction) - that form multifunctional enzymes with restriction (EC:3.1.21.3), methylase (EC:2.1.1.72) and ATPase activities. The S subunit is required for both restriction and modification and is responsible for recognition of the DNA sequence specific for the system. The M subunit is necessary for modification, and the R subunit is required for restriction. They recognize asymmetric DNA sequences split into two domains of specific sequence, one 3-4 bp long and another 4-5 bp long, separated by a nonspecific spacer 6-8 bp in length. Cleavage occurs a considerable distance from the recognition sites, rarely less than 400 bp away and up to 7000 bp away. Adenosyl residues are methylated, one on each strand of the recognition sequence; type I restriction-modification system modification subunit 3743221 hsdM 9793985 hsdM Arthrobacter arilaitensis Re117 type I restriction-modification system modification subunit YP_003918498.1 3741701 R 861360 CDS YP_003918499.1 308179093 9793980 complement(3743890..3745656) 1 NC_014550.1 hypothetical protein 3745656 9793980 AARI_33350 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918499.1 3743890 R 861360 CDS YP_003918500.1 308179094 9796977 3745798..3747246 1 NC_014550.1 hypothetical protein 3747246 9796977 AARI_33360 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918500.1 3745798 D 861360 CDS YP_003918501.1 308179095 9796978 3747243..3747923 1 NC_014550.1 hypothetical protein 3747923 9796978 AARI_33370 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918501.1 3747243 D 861360 CDS YP_003918502.1 308179096 9796981 3751298..3752446 1 NC_014550.1 hypothetical protein 3752446 9796981 AARI_33400 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918502.1 3751298 D 861360 CDS YP_003918503.1 308179097 9796982 complement(3753374..3754210) 1 NC_014550.1 presence of 2 conserved barrel domains of the cupin superfamily (PF07883); barrel domain-containing protein 3754210 9796982 AARI_33410 Arthrobacter arilaitensis Re117 barrel domain-containing protein YP_003918503.1 3753374 R 861360 CDS YP_003918504.1 308179098 9796983 complement(3754221..3755474) 1 NC_014550.1 hypothetical protein 3755474 9796983 AARI_33420 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918504.1 3754221 R 861360 CDS YP_003918505.1 308179099 9796984 complement(3755471..3757102) 1 NC_014550.1 catalyzes the aldol condensation of glyoxylate with acetyl-CoA to form malate, the second step of the glyoxylate bypass, an alternative to the tricarboxylic acid cycle in bacteria, fungi and plants; malate synthase 3757102 9796984 AARI_33430 Arthrobacter arilaitensis Re117 malate synthase YP_003918505.1 3755471 R 861360 CDS YP_003918506.1 308179100 9796985 complement(3757181..3758566) 1 NC_014550.1 catalyzes the oxidative decarboxylation of malate into pyruvate. Uses preferentially NAD and has the ability to decarboxylate oxaloacetate; malate dehydrogenase (oxaloacetate-decarboxylating) 3758566 9796985 AARI_33440 Arthrobacter arilaitensis Re117 malate dehydrogenase (oxaloacetate-decarboxylating) YP_003918506.1 3757181 R 861360 CDS YP_003918507.1 308179101 9796986 3758785..3759558 1 NC_014550.1 this family of bacterial transcriptional regulators groups several proteins, including gylR, a possible activator protein for the gylABX glycerol operon in Streptomyces, and iclR, the repressor of the acetate operon (also known as glyoxylate bypass operon) in Escherichia coli and Salmonella typhimurium; IclR family transcriptional regulator 3759558 9796986 AARI_33450 Arthrobacter arilaitensis Re117 IclR family transcriptional regulator YP_003918507.1 3758785 D 861360 CDS YP_003918508.1 308179102 9796987 complement(3759571..3761424) 1 NC_014550.1 TC 3.A.1.y.z. ABCISSE: ABC transporter, permease and ATP-binding protein (IM-ABC), DPL-family, prokaryote drug export (PED) subfamily. Possible function in in antibiotic peptide or drug resistance or production (export); drug resistance ATP-binding protein 3761424 9796987 AARI_33460 Arthrobacter arilaitensis Re117 drug resistance ATP-binding protein YP_003918508.1 3759571 R 861360 CDS YP_003918509.1 308179103 9796988 complement(3761698..3762294) 1 NC_014550.1 match to PF00440: bacterial regulatory proteins, tetR family; transcriptional regulator 3762294 9796988 AARI_33470 Arthrobacter arilaitensis Re117 transcriptional regulator YP_003918509.1 3761698 R 861360 CDS YP_003918510.1 308179104 9796989 3762488..3763519 1 NC_014550.1 identified by match to PF00248 family: Aldo/keto reductase family. This family includes a number of K+ ion channel beta chain regulatory domains - these are reported to have oxidoreductase activity; aldo-keto reductase family protein 3763519 9796989 AARI_33480 Arthrobacter arilaitensis Re117 aldo-keto reductase family protein YP_003918510.1 3762488 D 861360 CDS YP_003918511.1 308179105 9796990 3763595..3764389 1 NC_014550.1 identified by match to protein family PF00795. This family contains nitrilases that break carbon-nitrogen bonds and appear to be involved in the reduction of organic nitrogen compounds and ammonia production. They all have distinct substrate specificity and include cyanide hydratases, aliphatic amidases, beta-alanine synthase, and a few other proteins with unknown molecular function; carbon-nitrogen hydrolase 3764389 9796990 AARI_33490 Arthrobacter arilaitensis Re117 carbon-nitrogen hydrolase YP_003918511.1 3763595 D 861360 CDS YP_003918512.1 308179106 9796993 3765404..3766429 1 NC_014550.1 identified by match to PF01408 (oxidoreductase family, NAD-binding Rossmann fold); oxidoreductase domain-containing protein 3766429 9796993 AARI_33520 Arthrobacter arilaitensis Re117 oxidoreductase domain-containing protein YP_003918512.1 3765404 D 861360 CDS YP_003918513.1 308179107 9796994 complement(3766472..3767431) 1 NC_014550.1 catalyses the formation of UDP-glucose from UDP- galactose. Involved in the catabolism of galactose; UDP-glucose 4-epimerase 3767431 galE 9796994 galE Arthrobacter arilaitensis Re117 UDP-glucose 4-epimerase YP_003918513.1 3766472 R 861360 CDS YP_003918514.1 308179108 9793880 complement(3767428..3768624) 1 NC_014550.1 catalyzes the conversion of galactose to galactose 1-phosphate, first step of the Leloir pathway; galactokinase 3768624 galK 9793880 galK Arthrobacter arilaitensis Re117 galactokinase YP_003918514.1 3767428 R 861360 CDS YP_003918515.1 308179109 9793881 complement(3768621..3769736) 1 NC_014550.1 involved in conversion of galactose into alpha-D- glucose 1-phosphate, second step of the Leloir pathway; UDP-glucose--hexose-1-phosphate uridylyltransferase 3769736 galT 9793881 galT Arthrobacter arilaitensis Re117 UDP-glucose--hexose-1-phosphate uridylyltransferase YP_003918515.1 3768621 R 861360 CDS YP_003918516.1 308179110 9793882 complement(3769733..3770524) 1 NC_014550.1 DeoR-like transcription repressors occur in diverse bacteria as regulators of sugar and nucleoside metabolic systems. The effector molecules for deoR-like regulators are generally phosphorylated intermediates of the relevant metabolic pathway; DeoR family transcriptional regulator 3770524 9793882 AARI_33560 Arthrobacter arilaitensis Re117 DeoR family transcriptional regulator YP_003918516.1 3769733 R 861360 CDS YP_003918517.1 308179111 9796995 complement(3770813..3771415) 1 NC_014550.1 match to PF00440: bacterial regulatory proteins, tetR family; transcriptional regulator 3771415 9796995 AARI_33570 Arthrobacter arilaitensis Re117 transcriptional regulator YP_003918517.1 3770813 R 861360 CDS YP_003918518.1 308179112 9796996 3771597..3772937 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, carbohydrate uptake transporter-1 (CUT1) family (TC 3.A.1. 1.z). ABCISSE: ABC transporter, binding protein (BP), OSP-family (oligosaccharides or polyols); lactose ABC transporter substrate-binding protein 3772937 9796996 AARI_33580 Arthrobacter arilaitensis Re117 lactose ABC transporter substrate-binding protein YP_003918518.1 3771597 D 861360 CDS YP_003918519.1 308179113 9796997 3772934..3773866 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, carbohydrate uptake transporter-1 (CUT1) family (TC 3.A.1. 1.z). ABCISSE: ABC transporter, permease (IM), OSP- family (oligosaccharides or polyols); lactose ABC transporter inner membrane subunit 3773866 9796997 AARI_33590 Arthrobacter arilaitensis Re117 lactose ABC transporter inner membrane subunit YP_003918519.1 3772934 D 861360 CDS YP_003918520.1 308179114 9796998 3773863..3774738 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, carbohydrate uptake transporter-1 (CUT1) family (TC 3.A.1. 1.z). ABCISSE: ABC transporter, permease (IM), OSP- family (oligosaccharides or polyols); lactose ABC transporter inner membrane subunit 3774738 9796998 AARI_33600 Arthrobacter arilaitensis Re117 lactose ABC transporter inner membrane subunit YP_003918520.1 3773863 D 861360 CDS YP_003918521.1 308179115 9796999 3774735..3777863 1 NC_014550.1 hydrolysis of terminal non-reducing beta-D- galactose residues in beta-D-galactosides. Some enzymes in this group hydrolyze alpha-L-arabinosides; beta-galactosidase 3777863 lacZ 9796999 lacZ Arthrobacter arilaitensis Re117 beta-galactosidase YP_003918521.1 3774735 D 861360 CDS YP_003918522.1 308179116 9794028 complement(3777885..3778868) 1 NC_014550.1 identified by match to protein family PF1263. Aldose 1-epimerase (mutarotase) is the enzyme responsible for the anomeric interconversion of D-glucose and other aldoses (L-arabinose, D-xylose, D-galactose, maltose and lactose) between their alpha- and beta-forms; aldose 1-epimerase 3778868 9794028 AARI_33620 Arthrobacter arilaitensis Re117 aldose 1-epimerase YP_003918522.1 3777885 R 861360 CDS YP_003918523.1 308179117 9797000 complement(3778922..3780103) 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, carbohydrate uptake transporter-2 (CUT2) family (TC 3.A.1. 2.z). ABCISSE: ABCISSE: ABC transporter, permease (IM), MOS-family (monosaccharides: pentoses and hexoses). Possibly involved in the uptake of multiple sugars such as arabinose, xylose, galactose, glucose, fucose; multiple sugar ABC transporter inner membrane subunit 3780103 9797000 AARI_33630 Arthrobacter arilaitensis Re117 multiple sugar ABC transporter inner membrane subunit YP_003918523.1 3778922 R 861360 CDS YP_003918524.1 308179118 9797082 complement(3780100..3781638) 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, carbohydrate uptake transporter-2 (CUT2) family (TC 3.A.1. 2.z). ABCISSE: ABCISSE: ABC transporter, fused ATP- binding protein (ABC2), MOS-family (monosaccharides: pentoses and hexoses). Possibly involved in the uptake of multiple sugars such as arabinose, xylose, galactose, glucose, fucose; multiple sugar ABC transporter ATP-binding subunit 3781638 9797082 AARI_33640 Arthrobacter arilaitensis Re117 multiple sugar ABC transporter ATP-binding subunit YP_003918524.1 3780100 R 861360 CDS YP_003918525.1 308179119 9797083 complement(3781727..3782896) 1 NC_014550.1 TCDB: ATP-binding cassette (ABC) superfamily, carbohydrate uptake transporter-2 (CUT2) family (TC 3.A.1. 2.z). ABCISSE: ABCISSE: ABC transporter, binding protein (BP), MOS-family (monosaccharides: pentoses and hexoses). Possibly involved in the uptake of multiple sugars such as arabinose, xylose, galactose, glucose, fucose; multiple sugar ABC transporter substrate-binding protein 3782896 9797083 AARI_33650 Arthrobacter arilaitensis Re117 multiple sugar ABC transporter substrate-binding protein YP_003918525.1 3781727 R 861360 CDS YP_003918526.1 308179120 9797084 complement(3783072..3784583) 1 NC_014550.1 catalyzes the isomerization of L-arabinose to L- ribulose, the first reaction in its conversion into D- xylulose-5-phosphate, an intermediate in the pentose phosphate pathway, which allows L-arabinose to be used as a carbon source; L-arabinose isomerase 3784583 araA 9797084 araA Arthrobacter arilaitensis Re117 L-arabinose isomerase YP_003918526.1 3783072 R 861360 CDS YP_003918527.1 308179121 9793669 complement(3784591..3785307) 1 NC_014550.1 catalyses the following reaction: L-ribulose 5- phosphate <=> D-xylulose 5-phosphate. Involved in the metabolism of L-arabinose; L-ribulose-5-phosphate 4-epimerase 3785307 araD 9793669 araD Arthrobacter arilaitensis Re117 L-ribulose-5-phosphate 4-epimerase YP_003918527.1 3784591 R 861360 CDS YP_003918528.1 308179122 9793671 complement(3785333..3786946) 1 NC_014550.1 catalyzes the formation of L-ribulose 5-phosphate from L-ribulose. Involved in the catabolism of L- arabinose. Match to protein domain PF00370: FGGY family of carbohydrate kinases, N-terminal domain; ribulokinase 3786946 araB 9793671 araB Arthrobacter arilaitensis Re117 ribulokinase YP_003918528.1 3785333 R 861360 CDS YP_003918529.1 308179123 9793670 complement(3787116..3788171) 1 NC_014550.1 match to protein domain PF00356. Numerous bacterial transcription regulatory proteins bind DNA via a helix- turn-helix (HTH) motif. These proteins are very diverse, but for convenience may be grouped into subfamilies on the basis of sequence similarity. One such family groups together a range of proteins, including ascG, ccpA, cytR, ebgR, fruR, galR, galS, lacI, malI, opnR, purF, rafR, rbtR and scrR. Within this family, the HTH motif is situated towards the N-terminus; LacI family transcriptional regulator 3788171 9793670 AARI_33690 Arthrobacter arilaitensis Re117 LacI family transcriptional regulator YP_003918529.1 3787116 R 861360 CDS YP_003918530.1 308179124 9797085 complement(3788428..3789915) 1 NC_014550.1 nucleobase:cation symporter-2 (NCS2) Family (TC 2.A. 40.y.z). Match to protein family PF00860; xanthine/uric acid permease 3789915 9797085 AARI_33700 Arthrobacter arilaitensis Re117 xanthine/uric acid permease YP_003918530.1 3788428 R 861360 CDS YP_003918531.1 308179125 9797086 complement(3790039..3790962) 1 NC_014550.1 catalyses the formation of 5-hydroxyisourate from urate. The latter decomposes spontaneously to form allantoin; urate oxidase 3790962 9797086 AARI_33710 Arthrobacter arilaitensis Re117 urate oxidase YP_003918531.1 3790039 R 861360 CDS YP_003918532.1 308179126 9797087 complement(3790966..3791322) 1 NC_014550.1 identified by match to PF00576: HIUase/Transthyretin family. This family includes transthyretin that is a thyroid hormone-binding protein that transports thyroxine from the bloodstream to the brain. However, most of the sequences listed in this family do not bind thyroid hormones. They are actually enzymes of the purine catabolism that catalyse the conversion of 5-hydroxyisourate (HIU) to 5-hydroxy-2-oxo-4- ureido-2,5-dihydro-1H-imidazole-5- carboxylate (OHCU). HIU hydrolysis is the original function of the family and is conserved from bacteria to mammals; transthyretins arose by gene duplications in the vertebrate lineage; hydroxyisourate hydrolase 3791322 9797087 AARI_33720 Arthrobacter arilaitensis Re117 hydroxyisourate hydrolase YP_003918532.1 3790966 R 861360 CDS YP_003918533.1 308179127 9797088 complement(3791386..3791880) 1 NC_014550.1 hypothetical protein 3791880 9797088 AARI_33730 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918533.1 3791386 R 861360 CDS YP_003918534.1 308179128 9797089 3792205..3792399 1 NC_014550.1 hypothetical protein 3792399 9797089 AARI_33740 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918534.1 3792205 D 861360 CDS YP_003918535.1 308179129 9797090 complement(3792471..3792767) 1 NC_014550.1 hypothetical protein 3792767 9797090 AARI_33750 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918535.1 3792471 R 861360 CDS YP_003918536.1 308179130 9797091 complement(3792771..3793106) 1 NC_014550.1 hypothetical protein 3793106 9797091 AARI_33760 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918536.1 3792771 R 861360 CDS YP_003918537.1 308179131 9797092 complement(3793214..3794230) 1 NC_014550.1 Auxin Efflux Carrier (AEC) Family (TC 2.A.69.y.z). Homologues of the AEC family are found in bacteria as well as in archaea. The K. pneumoniae homologues has been implicated in malonate uptake, the O. oeni homologue is a malate permease; RHBT family transporter 3794230 9797092 AARI_33770 Arthrobacter arilaitensis Re117 RHBT family transporter YP_003918537.1 3793214 R 861360 CDS YP_003918538.1 308179132 9797093 3794428..3795192 1 NC_014550.1 identified by match to PF00106. The short-chain dehydrogenases/reductases family (SDR) is a very large family of enzymes, most of which are known to be NAD- or NADP-dependent oxidoreductases; short-chain dehydrogenases/reductases family protein 3795192 9797093 AARI_33780 Arthrobacter arilaitensis Re117 short-chain dehydrogenases/reductases family protein YP_003918538.1 3794428 D 861360 CDS YP_003918539.1 308179133 9797095 complement(3795611..3796060) 1 NC_014550.1 hypothetical protein 3796060 9797095 AARI_33800 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918539.1 3795611 R 861360 CDS YP_003918540.1 308179134 9797096 complement(3796108..3796365) 1 NC_014550.1 hypothetical protein 3796365 9797096 AARI_33810 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918540.1 3796108 R 861360 CDS YP_003918541.1 308179135 9797097 complement(3796453..3796914) 1 NC_014550.1 identified by match to protein family PF01047. Regulators with the marR-type HTH domain are present in bacteria and archaea and control a variety of biological functions, including resistance to multiple antibiotics, household disinfectants, organic solvents, oxidative stress agents and regulation of the virulence factor synthesis in pathogens of humans and plants. Many of the marR-like regulators respond to aromatic compounds; MarR family transcriptional regulator 3796914 9797097 AARI_33820 Arthrobacter arilaitensis Re117 MarR family transcriptional regulator YP_003918541.1 3796453 R 861360 CDS YP_003918542.1 308179136 9797098 3797038..3798039 1 NC_014550.1 identified by match to PF02678. Pirin was identified to be a metal-binding protein, and it was found that the metal-binding residues of Pirins are highly conserved across mammals, plants, fungi, and prokaryotic organisms; pirin-like protein 3798039 9797098 AARI_33830 Arthrobacter arilaitensis Re117 pirin-like protein YP_003918542.1 3797038 D 861360 CDS YP_003918543.1 308179137 9797099 3798057..3798389 1 NC_014550.1 identified by match to PF00583: acetyltransferase (GNAT) family; GNAT family acetyltransferase 3798389 9797099 AARI_33840 Arthrobacter arilaitensis Re117 GNAT family acetyltransferase YP_003918543.1 3798057 D 861360 CDS YP_003918544.1 308179138 9797100 complement(3798386..3799768) 1 NC_014550.1 major facilitator superfamily, drug:H+ antiporter-2 (14 spanner) (DHA2) family (TC 2.A.1.3.z). Match to PR01036: Tetracycline resistance protein TetB signature; multidrug resistance efflux protein 3799768 9797100 AARI_33850 Arthrobacter arilaitensis Re117 multidrug resistance efflux protein YP_003918544.1 3798386 R 861360 CDS YP_003918545.1 308179139 9797102 3800171..3801574 1 NC_014550.1 match to protein family PF00929. This family includes a variety of exonuclease proteins, such as ribonuclease T and the epsilon subunit of DNA polymerase III; exonuclease 3801574 9797102 AARI_33870 Arthrobacter arilaitensis Re117 exonuclease YP_003918545.1 3800171 D 861360 CDS YP_003918546.1 308179140 9797103 complement(3801695..3802438) 1 NC_014550.1 signal peptide predicted by SignalP 3.0 HMM (probability: 0.832) with cleavage site probability 0.394 between position 23 and 24. 7 transmembrane helices predicted by TMHMM2.0 after the signal peptide; hypothetical protein 3802438 9797103 AARI_33880 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918546.1 3801695 R 861360 CDS YP_003918547.1 308179141 9797104 complement(3802501..3803856) 1 NC_014550.1 a homohexameric protein required for DNA replication. The homohexamer can form a ring around a single strand of DNA near a replication fork. DnaB is a DNA helicase which exhibits DNA-dependent ATPase activity; replicative DNA helicase 3803856 dnaB 9797104 dnaB Arthrobacter arilaitensis Re117 replicative DNA helicase YP_003918547.1 3802501 R 861360 CDS YP_003918548.1 308179142 9793821 complement(3804512..3805012) 1 NC_014550.1 identified by match to PF01613; flavin reductase-like domain protein 3805012 9793821 AARI_33900 Arthrobacter arilaitensis Re117 flavin reductase-like domain protein YP_003918548.1 3804512 R 861360 CDS YP_003918549.1 308179143 9797105 3805597..3807204 1 NC_014550.1 match to protein family PF00501. This family of enzymes includes luciferase, long chain fatty acid Co-A ligase, acetyl-CoA synthetase and various other closely- related synthetases; fatty acid--Co-A ligase 3807204 9797105 AARI_33910 Arthrobacter arilaitensis Re117 fatty acid--Co-A ligase YP_003918549.1 3805597 D 861360 CDS YP_003918550.1 308179144 9797106 3807220..3807636 1 NC_014550.1 match to protein domain PF03061: thioesterase superfamily; thioesterase family domain-containing protein 3807636 9797106 AARI_33920 Arthrobacter arilaitensis Re117 thioesterase family domain-containing protein YP_003918550.1 3807220 D 861360 CDS YP_003918551.1 308179145 9797107 3808378..3808674 1 NC_014550.1 2 transmembrane helices predicted by TMHMM2.0; hypothetical protein 3808674 9797107 AARI_33930 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918551.1 3808378 D 861360 CDS YP_003918552.1 308179146 9797108 3808871..3809149 1 NC_014550.1 3 transmembrane helices predicted by TMHMM2.0; hypothetical protein 3809149 9797108 AARI_33940 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918552.1 3808871 D 861360 CDS YP_003918553.1 308179147 9797109 3809244..3809834 1 NC_014550.1 match to protein domain PF01872. This domain is found in the C-terminus of the bifunctional deaminase- reductase in combination with PF00383 as well as in isolation in some archaebacterial proteins; RibD domain-containing protein 3809834 9797109 AARI_33950 Arthrobacter arilaitensis Re117 RibD domain-containing protein YP_003918553.1 3809244 D 861360 CDS YP_003918554.1 308179148 9797110 3809842..3810900 1 NC_014550.1 identified by match to PF07995. Proteins containing this domain are thought to be glucose/sorbosone dehydrogenases. Quinoprotein glucose dehydrogenase catalyses the following reaction: D-glucose + ubiquinone => D-glucono-1,5-lactone + ubiquinol. It is a PQQ- containing quinoprotein that catalyzes a direct oxidation of D-glucose to D-gluconate in the periplasm of some bacteria and concomitantly transfers electrons to ubiquinol oxidase through ubiquinone in the respiratory chain. Signal peptide predicted by SignalP 3.0 HMM (probability: 0.982) with cleavage site probability 0.254 between position 48 and 49; quinoprotein glucose dehydrogenase 3810900 9797110 AARI_33960 Arthrobacter arilaitensis Re117 quinoprotein glucose dehydrogenase YP_003918554.1 3809842 D 861360 CDS YP_003918555.1 308179149 9797111 complement(3810995..3812512) 1 NC_014550.1 identified by similarity to protein SP:P38946 (Clostridium kluyveri). Succinyl-CoA:coenzyme A transferase forms succinyl-CoA from succinate and acetyl- CoA and is believed to be involved in anaerobic succinate degradation; succinyl-CoA:coenzyme A transferase 3812512 cat1 9797111 cat1 Arthrobacter arilaitensis Re117 succinyl-CoA:coenzyme A transferase YP_003918555.1 3810995 R 861360 CDS YP_003918556.1 308179150 9793727 complement(3812727..3813032) 1 NC_014550.1 match to PF01381: helix-turn-helix. This is large family of DNA binding helix-turn helix proteins that include a bacterial plasmid copy control protein, bacterial methylases, various bacteriophage transcription control proteins and a vegetative specific protein from Dictyostelium discoideum (Slime mould); hypothetical protein 3813032 9793727 AARI_33980 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918556.1 3812727 R 861360 CDS YP_003918557.1 308179151 9797112 complement(3813318..3813776) 1 NC_014550.1 binds to the 23S rRNA; 50S ribosomal protein L9 3813776 rplI 9797112 rplI Arthrobacter arilaitensis Re117 50S ribosomal protein L9 YP_003918557.1 3813318 R 861360 CDS YP_003918558.1 308179152 9794316 complement(3813797..3814036) 1 NC_014550.1 part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6; 30S ribosomal protein S18 3814036 rpsR 9794316 rpsR Arthrobacter arilaitensis Re117 30S ribosomal protein S18 YP_003918558.1 3813797 R 861360 CDS YP_003918559.1 308179153 9794365 complement(3814098..3814667) 1 NC_014550.1 this protein is essential for replication of the chromosome. It is also involved in DNA recombination and repair; single-stranded DNA-binding protein 3814667 ssb 9794365 ssb Arthrobacter arilaitensis Re117 single-stranded DNA-binding protein YP_003918559.1 3814098 R 861360 CDS YP_003918560.1 308179154 9794405 complement(3814723..3815019) 1 NC_014550.1 binds together with S18 to 16S ribosomal RNA; 30S ribosomal protein S6 3815019 rpsF 9794405 rpsF Arthrobacter arilaitensis Re117 30S ribosomal protein S6 YP_003918560.1 3814723 R 861360 CDS YP_003918561.1 308179155 9794353 complement(3815191..3817278) 1 NC_014550.1 match to protein domain PF01757. This family includes a range of acyltransferase enzymes. 9 transmembrane helices predicted by TMHMM2.0; acyltransferase domain-containing membrane protein 3817278 9794353 AARI_34030 Arthrobacter arilaitensis Re117 acyltransferase domain-containing membrane protein YP_003918561.1 3815191 R 861360 CDS YP_003918562.1 308179156 9797113 complement(3817396..3817887) 1 NC_014550.1 match to PF01381: helix-turn-helix. This is large family of DNA binding helix-turn helix proteins that include a bacterial plasmid copy control protein, bacterial methylases, various bacteriophage transcription control proteins and a vegetative specific protein from Dictyostelium discoideum (Slime mould); hypothetical protein 3817887 9797113 AARI_34040 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918562.1 3817396 R 861360 CDS YP_003918563.1 308179157 9797114 complement(3818027..3818578) 1 NC_014550.1 hypothetical protein 3818578 9797114 AARI_34050 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918563.1 3818027 R 861360 CDS YP_003918564.1 308179158 9797115 complement(3818673..3819953) 1 NC_014550.1 match to protein family PF02127. This group of metallopeptidases belong to the MEROPS peptidase family M18, (clan MH). The catalysed reaction involves the release of an N-terminal aminoacid, usually neutral or hydrophobic, from a polypeptide; M18 family aminopeptidase 3819953 9797115 AARI_34060 Arthrobacter arilaitensis Re117 M18 family aminopeptidase YP_003918564.1 3818673 R 861360 CDS YP_003918565.1 308179159 9797116 3820194..3820580 1 NC_014550.1 2 transmembrane helices predicted by TMHMM2.0; hypothetical protein 3820580 9797116 AARI_34070 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918565.1 3820194 D 861360 CDS YP_003918566.1 308179160 9797117 complement(3820648..3821352) 1 NC_014550.1 response regulators are key elements in two- component signal transduction systems, which enable bacteria to sense, respond, and adapt to a wide range of environments, stressors, and growth conditions; two-component system response regulator 3821352 9797117 AARI_34080 Arthrobacter arilaitensis Re117 two-component system response regulator YP_003918566.1 3820648 R 861360 CDS YP_003918567.1 308179161 9797118 complement(3821349..3822644) 1 NC_014550.1 protein-histidine kinases are key elements in two- component signal transduction systems, which enable bacteria to sense, respond, and adapt to a wide range of environments, stressors, and growth conditions. 5 transmembrane helices predicted by TMHMM2.0; signal transduction histidine kinase 3822644 9797118 AARI_34090 Arthrobacter arilaitensis Re117 signal transduction histidine kinase YP_003918567.1 3821349 R 861360 CDS YP_003918568.1 308179162 9797119 complement(3822679..3823524) 1 NC_014550.1 TC 3.A.1.y.z. ABCISSE: ABC transporter, permease (IM), DRI-family, DRB-subfamily (drug resistance, ). Possible function in drug efflux; drug ABC transporter inner membrane subunit 3823524 9797119 AARI_34100 Arthrobacter arilaitensis Re117 drug ABC transporter inner membrane subunit YP_003918568.1 3822679 R 861360 CDS YP_003918569.1 308179163 9797120 complement(3823529..3824455) 1 NC_014550.1 TC 3.A.1.y.z. ABCISSE: ABC transporter, ATP-binding protein (ABC), DRI-family, DRB-subfamily (drug resistance, ). Possible function in drug efflux; drug resistance ATP-binding protein 3824455 9797120 AARI_34110 Arthrobacter arilaitensis Re117 drug resistance ATP-binding protein YP_003918569.1 3823529 R 861360 CDS YP_003918570.1 308179164 9797121 complement(3824594..3825622) 1 NC_014550.1 6 transmembrane helices predicted by TMHMM2.0; hypothetical protein 3825622 9797121 AARI_34120 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918570.1 3824594 R 861360 CDS YP_003918571.1 308179165 9797122 complement(3825629..3827062) 1 NC_014550.1 hypothetical protein 3827062 9797122 AARI_34130 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918571.1 3825629 R 861360 CDS YP_003918572.1 308179166 9797123 complement(3827059..3828522) 1 NC_014550.1 8 transmembrane helices predicted by TMHMM2.0; hypothetical protein 3828522 9797123 AARI_34140 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918572.1 3827059 R 861360 CDS YP_003918573.1 308179167 9797124 3828762..3829946 1 NC_014550.1 match to protein family PF02348. EC 2.7.7.43 catalyzes the reaction of CTP and NeuAc to form CMP-NeuAc, which is the nucleotide sugar donor used by sialyltransferases. The outer membrane lipooligosaccharides of some microorganisms contain terminal sialic acid attached to N-acetyllactosamine; N-acylneuraminate cytidylyltransferase 3829946 9797124 AARI_34150 Arthrobacter arilaitensis Re117 N-acylneuraminate cytidylyltransferase YP_003918573.1 3828762 D 861360 CDS YP_003918574.1 308179168 9797125 3829959..3830852 1 NC_014550.1 match to protein family PF03102. EC 2.5.1.57 catalyses the direct formation of Neu5Ac (the most common sialic acid) by condensation of phosphoenolpyruvate (PEP) and N-acetylmannosamine (ManNAc); N-acylneuraminate-9-phosphate synthase 3830852 9797125 AARI_34160 Arthrobacter arilaitensis Re117 N-acylneuraminate-9-phosphate synthase YP_003918574.1 3829959 D 861360 CDS YP_003918575.1 308179169 9797126 3830929..3831936 1 NC_014550.1 match to PF00535: glycosyl transferase family 2. This domain is found in a diverse family of glycosyl transferases that transfer the sugar from UDP-glucose, UDP- N-acetyl-galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids; glycosyl transferase family 2 3831936 9797126 AARI_34170 Arthrobacter arilaitensis Re117 glycosyl transferase family 2 YP_003918575.1 3830929 D 861360 CDS YP_003918576.1 308179170 9797127 3831933..3833276 1 NC_014550.1 hypothetical protein 3833276 9797127 AARI_34180 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918576.1 3831933 D 861360 CDS YP_003918577.1 308179171 9797128 3833273..3834298 1 NC_014550.1 hypothetical protein 3834298 9797128 AARI_34190 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918577.1 3833273 D 861360 CDS YP_003918578.1 308179172 9797129 3834295..3835539 1 NC_014550.1 hypothetical protein 3835539 9797129 AARI_34200 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918578.1 3834295 D 861360 CDS YP_003918579.1 308179173 9797130 3835835..3836920 1 NC_014550.1 inositol-3-phosphate synthase is also named myo- inositol-1-phosphate synthase. It catalyses the conversion of glucose-6- phosphate to inositol-1-phosphate, which is then dephosphorylated to inositol. Inositol phosphates play an important role in signal transduction; inositol-3-phosphate synthase 3836920 9797130 AARI_34210 Arthrobacter arilaitensis Re117 inositol-3-phosphate synthase YP_003918579.1 3835835 D 861360 CDS YP_003918580.1 308179174 9797131 complement(3837106..3837228) 1 NC_014550.1 hypothetical protein 3837228 9797131 AARI_34220 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918580.1 3837106 R 861360 CDS YP_003918581.1 308179175 9797132 complement(3837813..3839264) 1 NC_014550.1 identified by match to protein family TIGR02692. Can add or repair the required CCA triplet at the 3 -end of tRNA molecules; tRNA adenylyltransferase 3839264 9797132 AARI_34230 Arthrobacter arilaitensis Re117 tRNA adenylyltransferase YP_003918581.1 3837813 R 861360 CDS YP_003918582.1 308179176 9797133 3839389..3839928 1 NC_014550.1 identified by match to PF00293. Members of the Nudix hydrolase superfamily catalyze the hydrolysis of nucleoside diphosphates linked to other moieties. Substrates of nudix hydrolases include intact and oxidatively damaged nucleoside triphosphates, dinucleoside polyphosphates, nucleotide-sugars and dinucleotide enzymes. These substrates are metabolites or cell signaling molecules that require regulation during different stages of the cell cycle or during periods of stress. In general, the role of the nudix hydrolase is to sanitize the nucleotide pools and to maintain cell viability, thereby serving as surveillance and house- cleaning enzymes; NUDIX hydrolase 3839928 9797133 AARI_34240 Arthrobacter arilaitensis Re117 NUDIX hydrolase YP_003918582.1 3839389 D 861360 CDS YP_003918583.1 308179177 9797134 3840044..3841675 1 NC_014550.1 identified by match to protein family PF03023. Deletion of the mviN virulence gene in Salmonella enterica serovar. Typhimurium greatly reduces virulence in a mouse model of typhoid-like disease. Open reading frames encoding homologues of MviN have since been identified in a variety of bacteria including pathogens and non- pathogens and plant-symbionts. In the nitrogen-fixing symbiont Rhizobium tropici, mviN is required for motility. The MviM protein is predicted to be membrane-associated; MviN-like protein 3841675 9797134 AARI_34250 Arthrobacter arilaitensis Re117 MviN-like protein YP_003918583.1 3840044 D 861360 CDS YP_003918584.1 308179178 9797135 3841799..3843418 1 NC_014550.1 1 transmembrane helice predicted by TMHMM2.0; hypothetical protein 3843418 9797135 AARI_34260 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918584.1 3841799 D 861360 CDS YP_003918585.1 308179179 9797136 3843519..3844484 1 NC_014550.1 catalyses the following reaction: thioredoxin + NADP(+) <=> thioredoxin disulfide + NADPH. It supplies reducing equivalents for a wide variety of reactions, for example for pyrimidine synthesis; thioredoxin-disulfide reductase 3844484 trxB 9797136 trxB Arthrobacter arilaitensis Re117 thioredoxin-disulfide reductase YP_003918585.1 3843519 D 861360 CDS YP_003918586.1 308179180 9794481 3844513..3844836 1 NC_014550.1 serves as a general protein disulphide oxidoreductase. It interacts with a broad range of proteins by a redox mechanism based on reversible oxidation of 2 cysteine thiol groups to a disulphide, accompanied by the transfer of 2 electrons and 2 protons. The net result is the covalent interconversion of a disulphide and a dithiol; thioredoxin 3844836 trx 9794481 trx Arthrobacter arilaitensis Re117 thioredoxin YP_003918586.1 3844513 D 861360 CDS YP_003918587.1 308179181 9794480 3846213..3847775 1 NC_014550.1 transposase of ISAar33, IS21 family, istA 3847775 istA 9794480 istA Arthrobacter arilaitensis Re117 transposase of ISAar33, IS21 family, istA YP_003918587.1 3846213 D 861360 CDS YP_003918588.1 308179182 9794018 3847772..3848518 1 NC_014550.1 helper of transposition of ISAar33, IS21 family, istB 3848518 istB 9794018 istB Arthrobacter arilaitensis Re117 helper of transposition of ISAar33, IS21 family, istB YP_003918588.1 3847772 D 861360 CDS YP_003918589.1 308179183 9794022 complement(3853028..3853975) 1 NC_014550.1 identified by match to TIGR00180. This HMM represents the most well-conserved core of a set of chromosomal and plasmid partition proteins related to ParB, including Spo0J, RepB, and SopB. Spo0J has been shown to bind a specific DNA sequence that, when introduced into a plasmid, can serve as partition site. Study of RepB, which has nicking-closing activity, suggests that it forms a transient protein-DNA covalent intermediate during the strand transfer reaction; chromosome-partitioning protein ParB 3853975 parB 9794022 parB Arthrobacter arilaitensis Re117 chromosome-partitioning protein ParB YP_003918589.1 3853028 R 861360 CDS YP_003918590.1 308179184 9794177 complement(3854867..3855790) 1 NC_014550.1 ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the initiation of DNA replication. ParB regulates the ParA ATPase activity by promoting nucleotide exchange in a fashion reminiscent of the exchange factors of eukaryotic G proteins. ADP-bound ParA binds single- stranded DNA, whereas the ATP-bound form dissociates ParB from its DNA binding sites. Increasing the fraction of ParA-ADP in the cell inhibits cell division, suggesting that this simple nucleotide switch may regulate cytokinesis; chromosome-partitioning protein ParA 3855790 parA 9794177 parA Arthrobacter arilaitensis Re117 chromosome-partitioning protein ParA YP_003918590.1 3854867 R 861360 CDS YP_003918591.1 308179185 9794176 complement(3855968..3856609) 1 NC_014550.1 GidB (glucose-inhibited division protein B) appears to be present and in a single copy in all complete eubacterial genomes so far. Its mode of action is unknown, but a methytransferase fold is reported from the crystal structure. It may be a family of bacterial glucose inhibited division proteins that are involved in the regulation of cell division; glucose-inhibited division protein B 3856609 gidB 9794176 gidB Arthrobacter arilaitensis Re117 glucose-inhibited division protein B YP_003918591.1 3855968 R 861360 CDS YP_003918592.1 308179186 9793898 complement(3856655..3857182) 1 NC_014550.1 identified by match to protein domain PF01424. The function of the domain is predicted to be binding ssDNA; R3H domain-containing protein 3857182 9793898 AARI_34320 Arthrobacter arilaitensis Re117 R3H domain-containing protein YP_003918592.1 3856655 R 861360 CDS YP_003918593.1 308179187 9797137 complement(3857185..3858159) 1 NC_014550.1 The preprotein translocase itself comprises 7 proteins, including a chaperone protein (SecB), an ATPase (SecA), an integral membrane complex (SecCY, SecE and SecG), and two additional membrane proteins that promote the release of the mature peptide into the periplasm (SecD and SecF). Other cytoplasmic/periplasmic proteins play a part in preprotein translocase activity, namely YidC and YajC. The latter is bound in a complex to SecD and SecF, and plays a part in stabilising and regulating secretion through the SecYEG integral membrane component via SecA; preprotein translocase subunit YidC 3858159 yidC 9797137 yidC Arthrobacter arilaitensis Re117 preprotein translocase subunit YidC YP_003918593.1 3857185 R 861360 CDS YP_003918594.1 308179188 9794517 complement(3858159..3858536) 1 NC_014550.1 hypothetical protein 3858536 9794517 AARI_34340 Arthrobacter arilaitensis Re117 hypothetical protein YP_003918594.1 3858159 R 861360 CDS YP_003918595.1 308179189 9797138 complement(3858536..3858889) 1 NC_014550.1 identified by match to protein family PF00825. Ribonuclease P (EC 3.1.26.5) is a site specific endonuclease that generates mature tRNAs by cleaving-off the leader sequences at their 5 ends. In bacteria RNase P is known to be composed of two components: a large (about 400 base pairs) RNA (gene rnpB) and a small protein (119 to 133 amino acids) (gene rnpA); ribonuclease P protein component 3858889 rnpA 9797138 rnpA Arthrobacter arilaitensis Re117 ribonuclease P protein component YP_003918595.1 3858536 R 861360 CDS YP_003918596.1 308179190 9794306 complement(3858954..3859091) 1 NC_014550.1 one of the proteins from the large subunit of the prokaryotic ribosome; 50S ribosomal protein L34 3859091 rpmH 9794306 rpmH Arthrobacter arilaitensis Re117 50S ribosomal protein L34 YP_003918596.1 3858954 R 861360 CDS