-- dump date 20140618_194024 -- class Genbank::CDS -- table cds_note -- id note YP_002261491.1 Similar to Escherichia coli Protein traY UniProt:P05835 (75 aa) fasta scores: E()=0.0012, 53.846% id in 39 aa YP_002261492.1 Similar to Escherichia coli Fimbrial protein precursor (Pilin) TraA UniProt:P14496 (119 aa) fasta scores: E()=0.11, 35.955% id in 89 aa YP_002261493.1 Similar to Salmonella pullorum Protein TraL UniProt:Q7BCG6 (103 aa) fasta scores: E()=0.0075, 27.174% id in 92 aa YP_002261494.1 Similar to Escherichia coli Protein TraE UniProt:Q46998 (188 aa) fasta scores: E()=4.6e-07, 29.487% id in 156 aa YP_002261495.1 Similar to Escherichia coli Protein TraK UniProt:Q47003 (242 aa) fasta scores: E()=0.00028, 23.137% id in 255 aa YP_002261496.1 Similar to Salmonella typhi Protein TraB UniProt:Q8KNL7 (453 aa) fasta scores: E()=3.7e-28, 29.399% id in 466 aa YP_002261498.1 Similar to Escherichia coli Protein TraC UniProt:P18004 (875 aa) fasta scores: E()=3.4e-62, 29.870% id in 847 aa YP_002261499.1 Similar to Salmonella typhi Protein TrbI UniProt:Q8KNL0 (154 aa) fasta scores: E()=3.1e-07, 34.579% id in 107 aa; trbi YP_002261503.1 TraN; TrhN; involved in stabilizing mating pairs during plasmid conjugation; F plasmid TraN appears to recognize OmpA in the recipient cell YP_002261504.1 Similar to Escherichia coli Protein TraF UniProt:P14497 (247 aa) fasta scores: E()=1.4e-17, 30.078% id in 256 aa YP_002261530.1 Weakly similar to Escherichia coli Plasmid partition protein A UniProt:P07620 (398 aa) fasta scores: E()=4.6e-09, 27.155% id in 232 aa YP_002261531.1 Weakly similar to Escherichia coli Protein sopB (Plasmid partition protein B) UniProt:P62558 (EMBL:X04619 (323 aa) fasta scores: E()=1.1e-09, 29.392% id in 296 aa YP_002261545.1 Similar to Streptomyces thermoviolaceus Beta-N-Acetylglucosaminidase precursor UniProt:O82840 (632 aa) fasta scores: E()=3.2e-09, 24.260% id in 507 aa YP_002261563.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group YP_002261564.1 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE YP_002261565.1 functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria YP_002261566.1 protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates YP_002261567.1 in Escherichia coli transcription of this gene is enhanced by polyamines YP_002261570.1 Similar to Escherichia coli Cystine-binding periplasmic protein precursor FliY UniProt:P0AEM9 (266 aa) fasta scores: E()=6.8e-24, 40.969% id in 227 aa YP_002261571.1 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself. YP_002261572.1 binds the polymerase to DNA and acts as a sliding clamp YP_002261573.1 Required for DNA replication; binds preferentially to single-stranded, linear DNA YP_002261574.1 negatively supercoils closed circular double-stranded DNA YP_002261578.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth YP_002261586.1 Expression may be regulated by Fur YP_002261588.1 Similar to Escherichia coli o157:h- Plasmid pSFO157 Wb0013. UniProt:Q8VU43 (262 aa) fasta scores: E()=2.3e-08,24.254% id in 268 aa YP_002261601.1 Similar to Escherichia coli acyltransferase YihG UniProt:P32129 (310 aa) fasta scores: E()=5.3e-48, 42.612% id in 291 aa YP_002261603.1 catalyzes the phosphorylation of protein substrates at serine and threonine residues in vitro; specific substrate in vivo has not been identified yet; plays a role in long-term cell survival and expression of surface appendages YP_002261604.1 Expression may be regulated by Fur YP_002261610.1 threonine deaminase; threonine dehydratase; in Escherichia coli, IlvA is part of the isoleucine biosynthetic pathway YP_002261611.1 The CDS appears to have a deletion of 130 amino acid residues after codon 297 in comparison to orthologues YP_002261614.1 Expression may be regulated by Fur YP_002261615.1 Similar to Bacillus subtilis Sporulation initiation inhibitor protein Soj UniProt:P37522 (253 aa) fasta scores: E()=1.6e-13, 32.389% id in 247 aa YP_002261624.1 involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain YP_002261625.1 Possible alternative translational start site after codon 18 YP_002261626.1 modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth YP_002261627.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+) YP_002261631.1 Similar to Bacillus subtilis DNA topoisomerase 1 TopA UniProt:P39814 (691 aa) fasta scores: E()=2e-10,32.258% id in 124 aa YP_002261632.1 With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway YP_002261635.1 AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate YP_002261636.1 Similar to Vibrio fischeri Hypothetical protein UniProt:Q5E1R7 (87 aa) fasta scores: E()=7e-11, 65.000% id in 60 aa YP_002261638.1 participates in controlling several genes involved in isoleucine and valine biosynthesis; activates the transcription of the ilvC gene in the presence of acetolactate or acetohydroxybutyrate YP_002261639.1 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis YP_002261641.1 Similar to Escherichia coli Acriflavine resistance protein F AcrF UniProt:P24181 (1034 aa) blastp scores: E()=0e-130 YP_002261642.1 Similar to Pseudomonas aeruginosa Multidrug transporter membrane fusion protein MexA (PDB 1VF7),evalue=3e-21, identity=(80, 326) YP_002261647.1 Similar to Bacillus subtilis Oligopeptide transport system permease protein AppB UniProt:P42062 (317 aa) fasta scores: E()=1e-32, 34.161% id in 322 aa YP_002261649.1 Similar to Bacillus subtilis Glycine betaine transporter OpuD UniProt:P54417 (512 aa) fasta scores: E()=4.2e-65, 41.968% id in 498 aa YP_002261650.1 3'-5' exonuclease of DNA polymerase III YP_002261657.1 Catalyzes the reversible hydrolysis of the amide bond within dihydroorotate. This metabolic intermediate is required for the biosynthesis of pyrimidine nucleotides YP_002261671.1 catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense YP_002261675.1 defects in the mitochondrial frataxin protein cause Friedreich ataxis which is an autosomal recessive neurodegenerative disease; based on phylogenomic distribution this protein may have a role in iron-sulfur cluster protein assembly YP_002261677.1 involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate YP_002261679.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs YP_002261684.1 Similar to Rhizobium meliloti L-2,4-diaminobutyrate decarboxylase, UniProt:Q9Z3R1 (495 aa) fasta scores: E()=3e-36, 36.034% id in 469 aa. Expression may be regulated by Fur YP_002261685.1 Similar to Escherichia coli L-lysine 6-monooxygenase IucD UniProt:P11295 (425 aa) fasta scores: E()=7.3e-46, 33.021% id in 427 aa YP_002261686.1 Similar to Vibrio hollisae Aerobactin synthetase IucC UniProt:Q4H460 (586 aa) fasta scores: E()=3.9e-49,30.100% id in 598 aa. Possible alternative translational start site after codon 56 YP_002261687.1 Similar to Pseudomonas aeruginosa Ferripyoverdine receptor precursor FpvA UniProt:P48632 (815 aa) fasta scores: E()=4.5e-83, 36.483% id in 688 aa YP_002261688.1 Similar to Escherichia coli Ferrienterobactin-binding periplasmic protein precursor FepB UniProt:P0AEL6 (318 aa) fasta scores: E()=4.8e-05,21.908% id in 283 aa YP_002261690.1 Similar to Vibrio cholerae Cytoplasmic membrane permease (viuG); id 34.328%; ungapped id 35.276%; E()=5.4e-27; 335 aa overlap YP_002261691.1 Similar to Vibrio cholerae ATPase (viuC); length=279; id 49.802%; ungapped id 50.000%; E()=7.2e-40; 253 aa overlap YP_002261695.1 enables ATP-dependent unwinding of double stranded RNA as a component of the RNA degradosome, a multi-enzyme complex important in RNA processing and messenger RNA degradation YP_002261697.1 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes YP_002261700.1 Similar to Equisetum telmateia (Giant horsetail) Ferredoxin-1 UniProt:P00234 (95 aa) fasta scores: E()=2.5e-08, 42.857% id in 84 aa YP_002261701.1 NAD(P)H-flavin reductase; catalyzes the reversible oxidation/reduction of NAD(P) and flavine mononucleotide; in Salmonella and E. coli this protein also reduces aquacob(III)alamin to cob(II)alamin YP_002261704.1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases YP_002261705.1 catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose YP_002261708.1 catalyzes the transfer of 2-keto-3-deoxy-D-manno-octulosonic acid to lipid A YP_002261711.1 Similar to Campylobacter jejuni PseA UniProt:Q939J7 (378 aa) fasta scores: E()=6.6e-39, 36.216% id in 370 aa YP_002261712.1 Similar to Campylobacter coli PtmE UniProt:Q7X521 (220 aa) fasta scores: E()=5.9e-31, 43.439% id in 221 aa YP_002261714.1 Similar to Campylobacter coli PtmC UniProt:Q7X523 (334 aa) fasta scores: E()=4.5e-31, 52.113% id in 355 aa YP_002261715.1 Similar to Campylobacter coli PtmD UniProt:Q7X522 (391 aa) fasta scores: E()=1.7e-50, 42.010% id in 388 aa YP_002261719.1 catalyzes the formation of dTDP-D-fucosamine from dTDP-4-oxo-6-deoxy-D-glucose in enterobacterial common antigen biosynthesis YP_002261725.1 catalyzes the phosphorylation of 3-deoxy-D-manno-octulosonic acid at the 4-OH position YP_002261728.1 Similar to Rhizobium meliloti lipopolysaccharide core biosynthesis glycosyl transferase LpsD UniProt:Q9R9N0 (343 aa) fasta scores: E()=1e-10, 25.852% id in 352 aa YP_002261729.1 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA YP_002261731.1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases YP_002261733.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif YP_002261734.1 required for 70S ribosome assembly YP_002261735.1 Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase YP_002261736.1 catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, which is then decarboxylated to form 4'-phosphopantotheine YP_002261737.1 FtsZ binding protein; synthetically lethal with a defect in the Min system; this protein is the first identified nucleoid occlusion factor which works along with the Min system to properly position the FtsZ ring assembly YP_002261738.1 Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA YP_002261739.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus YP_002261740.1 Similar to Escherichia coli S1 RNA binding domain (PDB 1SRO), evalue=5e-09 identity=(31, 75). Expression may be regulated by Fur YP_002261744.1 membrane-localized osmosensor; histidine kinase; in high osmolarity EnvZ autophosphorylates itself and transfers phosphoryl group to OmpR YP_002261745.1 part of two-component system EnvZ/OmpR; regulates transcription of outer membrane porin genes ompC/F; under high osmolarity EnvZ functions as kinase/phosphotransferase and phosphorylates OmpR; the result is increased expression of ompC and repression of ompF; also functions in regulation of other genes; forms dimers upon phosphorylation YP_002261746.1 Similar to Pseudomonas aeruginosa Partitioning protein ParA UniProt:Q4W1V5 (212 aa) fasta scores: E()=3.2e-05, 28.571% id in 168 aa YP_002261747.1 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate YP_002261748.1 RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs YP_002261751.1 Essential for recycling GMP and indirectly, cGMP YP_002261752.1 promotes RNA polymerase assembly or stability; latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits YP_002261758.1 Similar to Escherichia coli uroporphyrin-III C-methyltransferase HemX UniProt:P09127 (393 aa) fasta scores: E()=1.5e-36, 32.718% id in 379 aa. Possible alternative translational start site after codon 25 YP_002261760.1 transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis YP_002261761.1 catalyzes transfer of adenylyl group of ATP from pyrophosphate to the 3'-hydroxyl group to form cyclic AMP YP_002261762.1 unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present; involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair. YP_002261764.1 functions in blocking illegitimate recombination, enhancing topoisomerase activity, initiating SOS signaling and clearing blocked replication forks; component of the RecF recombinational pathway YP_002261767.1 has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair YP_002261768.1 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential YP_002261773.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III YP_002261777.1 Similar to Rhizobium meliloti lipopolysaccharide core biosynthesis glycosyl transferase LpsD UniProt:Q9R9N0 (EMBL:AF193023) (343 aa) fasta scores: E()=1e-10, 25.852% id in 352 aa YP_002261780.1 catalyzes the phosphorylation of 3-deoxy-D-manno-octulosonic acid at the 4-OH position YP_002261786.1 catalyzes the formation of dTDP-D-fucosamine from dTDP-4-oxo-6-deoxy-D-glucose in enterobacterial common antigen biosynthesis YP_002261790.1 Similar to Campylobacter coli PtmD UniProt:Q7X522 (391 aa) fasta scores: E()=1.7e-50, 42.010% id in 388 aa YP_002261791.1 Similar to Campylobacter coli PtmC UniProt:Q7X523 (334 aa) fasta scores: E()=4.5e-31, 52.113% id in 355 aa YP_002261793.1 Similar to Campylobacter coli PtmE UniProt:Q7X521 (220 aa) fasta scores: E()=5.9e-31, 43.439% id in 221 aa YP_002261794.1 Similar to Campylobacter jejuni PseA UniProt:Q939J7 (378 aa) fasta scores: E()=3.7e-39, 36.216% id in 370 aa YP_002261797.1 catalyzes the transfer of 2-keto-3-deoxy-D-manno-octulosonic acid to lipid A YP_002261799.1 Similar to Vibrio cholerae O-antigen ligase WaaL UniProt:Q8RJ54 (399 aa) fasta scores: E()=7e-14, 27.094% id in 406 aa YP_002261800.1 catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose YP_002261818.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate YP_002261821.1 type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese YP_002261826.1 regulator of RNase E; increases half-life and abundance of RNAs; interacts with RNase E possibly inhibiting catalytic activity YP_002261827.1 catalyzes the formation of dimethylmenaquinone from 1,4-dihydroxy-2-naphthoate and octaprenyl diphosphate YP_002261833.1 required for KefB activity YP_002261834.1 involved in potassium efflux YP_002261837.1 Similar to Escherichia coli Protein SlyX UniProt:P0A8R4 (72 aa) fasta scores: E()=1.4e-06, 37.313% id in 67 aa YP_002261841.1 in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs YP_002261844.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance YP_002261845.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit YP_002261846.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene YP_002261847.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu YP_002261851.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex YP_002261852.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin YP_002261853.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA YP_002261854.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel YP_002261855.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation YP_002261856.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA YP_002261857.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center YP_002261858.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation YP_002261859.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e YP_002261860.1 one of the stabilizing components for the large ribosomal subunit YP_002261861.1 primary binding protein; helps mediate assembly; involved in translation fidelity YP_002261862.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase YP_002261863.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel YP_002261864.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13 YP_002261865.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif YP_002261866.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit YP_002261867.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance YP_002261868.1 binds 5S rRNA along with protein L5 and L25 YP_002261869.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance YP_002261870.1 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7 YP_002261871.1 late assembly protein YP_002261872.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase YP_002261873.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA YP_002261874.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3 YP_002261875.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination YP_002261876.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme YP_002261877.1 is a component of the macrolide binding site in the peptidyl transferase center YP_002261878.1 catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate YP_002261881.1 part of the thiamine and TPP transport system tbpA-thiPQ YP_002261882.1 permease; with TbpA and ThiQ functions in transport of thiamine and thiamine pyrophosphate into the cell; repressed in presence of exogenous thiamine YP_002261884.1 transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA YP_002261889.1 regulates arginine biosynthesis when complexed with arginine by binding at site that overlap the promotors of the arginine biosynthesis genes YP_002261890.1 oxidizes malate to oxaloacetate YP_002261893.1 involved in the peptidyltransferase reaction during translation YP_002261894.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication YP_002261897.1 Expression may be regulated by Fur YP_002261898.1 hydrolyzes P(1),P(4)-bis(5'-adenosyl) tetraphosphate to form 2 ADP YP_002261899.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin YP_002261900.1 catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate) YP_002261902.1 determines N-hexane tolerance and is involved in outer membrane permeability YP_002261903.1 functions as a co-chaperone with DnaK; involved in regulation of colanic acid capsule; inner membrane protein; dimerized via transmembrane domain; J-like domain is cytoplasmic and can functionally substitute for DnaJ; stimulates synthesis of colanic acid mucoid capsule through the RcsB/C signal transduction system YP_002261905.1 catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D YP_002261906.1 dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate YP_002261907.1 catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis YP_002261908.1 catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis YP_002261911.1 130 amino acid residues longer than the V.fischeri homologue YP_002261912.1 unwinds double stranded DNA YP_002261913.1 converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer YP_002261915.1 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family YP_002261919.1 Similar to central part of Vibrio parahaemolyticus (Q8L0W3) Hypothetical protein (Fragment) YP_002261925.1 Weakly similar to Bacteriophage BFK20 ORF43 UniProt:Q3V5F2 (982 aa) fasta scores: E()=1.5e-11, 33.803% id in 213 aa YP_002261926.1 Similar to Escherichia coli Shufflon-specific DNA recombinase rci UniProt:P16470 (384 aa) fasta scores: E()=1e-14, 33.065% id in 248 aa YP_002261927.1 Similar to Escherichia coli Shufflon-specific DNA recombinase rci UniProt:P10487 (384 aa) fasta scores: E()=1.3e-11, 27.211% id in 294 aa YP_002261930.1 Alternative start at codon 15 YP_002261932.1 hemoprotein; NADPH dependent; with the alpha subunit (a flavoprotein) catalyzes the reduction of sulfite to sulfide YP_002261933.1 catalyzes the reduction of 3'-phosphoadenylyl sulfate into sulfite YP_002261934.1 Expression may be regulated by Fur YP_002261948.1 periplasmic enzyme; functions during ribonucleic acid degradation; 2',3'-cyclic nucleotides are first converted to 3'-nucleotide and then cleaved to yield a ribonucleotide and a phosphate YP_002261949.1 with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP YP_002261950.1 may be GTPase that regulates ATP sulfurylase activity that is involved in converting ATP and sulfate to diphosphate and adenylylsulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis in the first step; forms a heterodimer with CysD; part of the GTP-binding elongation factor family CysN/NodQ YP_002261952.1 converts ATP and adenylyl sulfate to ADP and 3'-phosphoadenylyl sulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis YP_002261960.1 Expression may be stress-induced YP_002261963.1 Similar to Vibrio fischeri Hypothetical outer membrane protein UniProt:Q5E818 (1266 aa) fasta scores: E()=0, 72.874% id in 1176 aa YP_002261968.1 CDS contanins a rare Leucine start codon (TTA) YP_002261970.1 one of two methionine synthases in Escherichia coli; MetH catalyzes a methyl transfer reaction from methyltetrahydrofolate to homocysteine to create methionine; requires zinc for activity YP_002261974.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate YP_002261985.1 Weakly similar to Vibrio parahaemolyticus CPS biosynthesis protein CpsB UniProt:Q847V4 (402 aa) fasta scores: E()=2e-14, 24.936% id in 393 aa YP_002261986.1 binds to single stranded DNA and PriA helcase facilitate replication restart YP_002261990.1 regulates the degradation of the small RNAs CsrB and CsrC; may function to targate RNase E to specific RNA molecules YP_002262000.1 Expression may be regulated by Fur YP_002262001.1 duplicate of TVS0304 YP_002262004.1 Weakly similar to Vibrio cholerae Hypothetical protein MshO UniProt:Q9ZA95 (256 aa) fasta scores: E()=2e-14, 28.846% id in 260 aa YP_002262005.1 Weakly similar to Vibrio cholerae MshP UniProt:Q9ZA94 (141 aa) fasta scores: E()=0.017, 28.676% id in 136 aa YP_002262006.1 functions in MreBCD complex in some organisms YP_002262007.1 in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall YP_002262008.1 part of cell wall structural complex MreBCD; transmembrane component YP_002262009.1 Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell YP_002262010.1 involved in the processing of the 5'end of 16S rRNA YP_002262015.1 protease involved in proteolytic processing of the antibiotic Microcin B17 and in sensitivity to the DNA gyrase inhibitor LetD YP_002262021.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma 54 factor is responsible for the expression of enzymes involved in nitrogen assimilation and metabolism; the rhizobia often have 2 copies of this sigma factor; in Rhizobium etli RpoN1 shown to be involved in the assimilation of several nitrogen and carbon sources during free-living aerobic growth and RpoN2 is involved in symbiotic nitrogen fixation; in Bradyrhizobium both RpoN1 and N2 are functional in free-living and symbiotic conditions, rpoN1 gene was regulated in response to oxygen YP_002262025.1 forms homotetramers; catalyzes hydrolysis of KDO 8-P to KDO and inorganic phosphate; functions in lipopolysaccharide biosynthesis YP_002262027.1 Similar to Escherichia coli Inner membrane protein YrbG UniProt:P45394 (325 aa) fasta scores: E()=9e-44,44.688% id in 320 aa YP_002262034.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active YP_002262039.1 involved in the allosteric regulation of aspartate carbamoyltransferase YP_002262040.1 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis YP_002262041.1 catalyzes the formation of ornithine and carbamylphosphate from citrulline in the arginine catabolic pathway YP_002262042.1 catalyzes the degradation of arginine to citruline and ammonia YP_002262045.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain YP_002262046.1 binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB YP_002262047.1 catalyzes the removal of N-terminal amino acids preferably leucine from various peptides YP_002262048.1 Similar to Escherichia coli Inner membrane protein YjgP UniProt:P0AF98 (366 aa) fasta scores: E()=2.7e-54,43.443% id in 366 aa YP_002262049.1 Similar to Escherichia coli Inner membrane protein YjgQ UniProt:P0ADC6 (360 aa) fasta scores: E()=2.6e-66,51.685% id in 356 aa YP_002262056.1 tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine YP_002262057.1 catalyzes the formation of glutamate from glutamine YP_002262058.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III YP_002262059.1 HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine YP_002262063.1 catalyzes the formation of L-proline from pyrroline-5-carboxylate YP_002262067.1 similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function YP_002262069.1 catalyzes the second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione YP_002262070.1 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase YP_002262072.1 Similar to Escherichia coli Protein SprT UniProt:P39902 (165 aa) fasta scores: E()=5.2e-31, 51.634% id in 153 aa YP_002262073.1 catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase YP_002262075.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase YP_002262076.1 NAD-dependent; catalyzes the formation of 4-phosphoerythronate from erythrose 4-phosphate in the biosynthesis of pyridoxine 5'-phosphate YP_002262077.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway YP_002262078.1 catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate YP_002262079.1 facilitates an early step in the assembly of the 50S subunit of the ribosome YP_002262082.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic YP_002262083.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; XerD specifically exchanges the bottom strands; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs YP_002262085.1 5'-3' single-stranded-DNA-specific exonuclease YP_002262086.1 class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1 YP_002262087.1 Similar to Escherichia coli Transcriptional regulatory protein ZraR UniProt:P14375 (441 aa) fasta scores: E()=2.5e-36, 34.197% id in 386 aa YP_002262088.1 MutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences during DNA repair YP_002262089.1 hydrolyzes diadenosine polyphosphate YP_002262090.1 member of a second PTS chain involved in nitrogen metabolism; PtsP phosphorylates NPr YP_002262092.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein YP_002262093.1 ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived YP_002262095.1 Na+/H+ antiporter regulatory protein; activates the genes nhaA and osmC YP_002262097.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase YP_002262099.1 catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities YP_002262100.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme YP_002262101.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis YP_002262103.1 catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway YP_002262104.1 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis YP_002262105.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers YP_002262106.1 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity YP_002262107.1 penicillin binding protein 4; penicillin sensitive; catalyzes the formation of D-alanine from D-alanyl-D-alanine; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains YP_002262108.1 In Vibrio anguillarum OmpU limits the progression of biofilm formation outside of the fish host. YP_002262109.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus YP_002262111.1 Specifically methylates the uridine in position 2552 of 23S rRNA in the fully assembled 50S ribosomal subunit YP_002262114.1 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate YP_002262116.1 in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins YP_002262117.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination YP_002262118.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex YP_002262119.1 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock YP_002262120.1 catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs YP_002262121.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence YP_002262123.1 lipoprotein that appears to be involved in cell division; interacts with the periplasmic protease Prc and may be activated by protease processing YP_002262130.1 Doubtful CDS, poor translational start site. No significant database matches to the full length CDS YP_002262133.1 stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein YP_002262138.1 Expression may be stress-induced YP_002262139.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate YP_002262140.1 Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate YP_002262141.1 catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose YP_002262143.1 catalyzes the formation of serine from O-phosphoserine YP_002262144.1 May be involved in signalling YP_002262145.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents YP_002262146.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene YP_002262148.1 Catalyzes the deamination of cytosine to uracil and ammonia YP_002262151.1 This protein performs the mismatch recognition step during the DNA repair process YP_002262153.1 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs YP_002262154.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_002262155.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP YP_002262156.1 affects carbohydrate metabolism; has regulatory role in many processes YP_002262158.1 catalyzes the formation of pyruvate from oxaloacetate YP_002262162.1 involved in the first step of glutathione biosynthesis YP_002262164.1 catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2 YP_002262168.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity YP_002262169.1 Essential for efficient processing of 16S rRNA YP_002262170.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA YP_002262171.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site YP_002262172.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, tyrosine sensitive YP_002262173.1 catalyzes the formation of prephenate from chorismate and the formation of 4-hydroxyphenylpyruvate from prephenate in tyrosine biosynthesis YP_002262177.1 When complexed with L-tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription YP_002262178.1 pyrophosphatase; has activity against dUTP and dITP; the crystal structure of the Vibrio protein showed similarity to Methanococcus janaschii Mj0226; in Vibrio cholerae this gene is part of the Mba operon that is involved in regulation and maintenance of biofilms; in Escherichia coli overexpression of this gene leads to resistance to an HMP analog YP_002262182.1 responsible for synthesis of pseudouridine from uracil at positions 1911, 1915 and 1917 in 23S ribosomal RNA YP_002262188.1 Similar to Pseudomonas aeruginosa Type 4 fimbrial biogenesis protein FimU UniProt:Q59652 (168 aa) fasta scores: E()=5.2e-05, 31.447% id in 159 aa YP_002262189.1 Similar to Pseudomonas aeruginosa Type 4 fimbrial biogenesis protein PilE UniProt:Q60148 (141 aa) fasta scores: E()=4.6e-08, 32.168% id in 143 aa YP_002262192.1 Large N-terminal truncation of around 110 amino acid residues compared with the Corynebacterium glutamicum orthologue YP_002262197.1 catalyzes ATP-dependent exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield 5'-phosphooligonucleotides; component of the RecBCD (Exo V) helicase/nuclease complex that is essential for recombination YP_002262199.1 CDS contains additional 60 internal amino acid residues in comparison to the E.coli orthologue YP_002262202.1 catalyzes the formation of N-acetyl-L-glutamate from L-glutamate and acetyl-CoA in arginine biosynthesis YP_002262203.1 Possible alternative translational start site after codon 1 YP_002262204.1 membrane-bound, lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues YP_002262206.1 Similar to Escherichia coli ygdk SufE-like protein YgdK. Members of the YgdK/SufE protein family are enhancers of cysteine desulfurases YP_002262208.1 Glycine cleavage system transcriptional activator; activates the gcvTHP operon in the presence of glycine and represses the operon in its absence YP_002262211.1 has 3'-5' exonuclease activity that preferentially acts on ssDNA; also 3'-phosphodiesterase activity at sites with 3' incised apurinic/apyrimidinic sites; can remove 3' phosphoglycolate groups YP_002262213.1 Expression may be regulated by Fur YP_002262215.1 catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) in queuosine biosynthesis YP_002262216.1 SecY regulator that either chelates excess SecY or negatively regulates the SecYE translocase function YP_002262220.1 Possible alternative translational start site after codon 7 YP_002262230.1 catalyzes formation of pseudouridine at position 65 in tRNA-Ile1 and tRNA-Asp YP_002262232.1 Similar to Escherichia coli Hypothetical tRNA/rRNA methyltransferase YfhQ UniProt:P0AE01 (246 aa) fasta scores: E()=6e-57, 63.934% id in 244 aa YP_002262233.1 Expression may be stress-induced YP_002262234.1 catalyzes the removal of elemental sulfur from cysteine to produce alanine; involved in NAD biosynthesis YP_002262235.1 Weakly similar to chain A, solution structure of iron-sulfur cluster assembly protein SufU From Bacillus subtilis (pdb 2AZ) identity=(33, 86) YP_002262237.1 J-type co-chaperone that regulates the ATPase and peptide-binding activity of Hsc66 chaperone; may function in biogenesis of iron-sulfur proteins YP_002262238.1 involved in the maturation of iron-sulfur cluster-containing proteins YP_002262240.1 Similar to hypothetical protein yfhJ (PDB 1UJ8). Evalue=6e-20, identity=(38, 62). Member of the ISC machinery of E.coli involved in assembly of iron-sulfur clusters YP_002262241.1 catalyzes the removal of an N-terminal amino acid from a peptide or arylamide YP_002262242.1 catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate YP_002262243.1 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance YP_002262246.1 catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis YP_002262247.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG YP_002262249.1 with YaeT, YfiO, and NlpB forms a complex involved in outer membrane protein biogenesis YP_002262250.1 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains YP_002262253.1 bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides YP_002262254.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate YP_002262255.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway YP_002262256.1 Expression may be regulated by Fur YP_002262262.1 Expression may be stress-induced YP_002262263.1 Similar to Alcaligenes eutrophus LysR-type Transcriptional Regulator CbnR (PDB 1IXC). Evalue=1e-06,identity=(26, 65) YP_002262265.1 YfhD; uncharacterized member of the transglycosylase slt family; part of the rob operon, which plays a role in cellular resistance to antibiotics, bactericidal agents, and organic solvents; unknown function YP_002262266.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis YP_002262267.1 Possible alternative translational start site after codon 7 YP_002262273.1 Expression may be regulated by Fur YP_002262284.1 Similar to Bacteriophage HP1 capsid scaffolding protein UniProt:P51719 (298 aa) fasta scores: E()=1e-15, 32.740% id in 281 aa YP_002262294.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1 YP_002262295.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation YP_002262296.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP YP_002262297.1 An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis YP_002262298.1 Incorporates lipoproteins in the outer membrane after they are released by the LolA protein YP_002262299.1 catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins YP_002262300.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2 YP_002262304.1 catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis YP_002262305.1 The CDS appears to be truncated at the N-terminus in comparison to orthologues. Although other vibrio orthologues are found to be of similar size YP_002262307.1 involved in reducing nitrite to ammonium to detoxify nitrite accumulation in anaerobic nitrate-respiring cells and regenerate NAD+; bounds to NirB, the cytoplasmic subunit, whose expression is induced at high nitrate concentrations YP_002262310.1 catalyzes the degradation of periplasmic UDP-glucose to uridine, glucose-1-phosphate and inorganic phosphate; specific for uridine nucleotides YP_002262312.1 CDS is extended at the N-terminus in comparison to orthologues other than vibrio orthologues YP_002262322.1 molecular chaperone YP_002262323.1 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP YP_002262324.1 protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic YP_002262325.1 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer YP_002262326.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates YP_002262329.1 Possible alternative translational start site after codon 8 YP_002262331.1 Expression may be regulated by Fur YP_002262334.1 functions in asparagine biosynthesis; converts glutamine, aspartate, ATP, and water to glutamate, asparagine, pyrophosphate and AMP YP_002262337.1 catalyzes the formation of glucosamine 6-phosphate from N-acetylglucosamine 6-phosphate YP_002262339.1 catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_002262340.1 negatively regulates a number of operons that encode enzymes involved in iron transport; activated by manganese; forms a homodimer YP_002262342.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group YP_002262344.1 Expression may be stress-induced YP_002262345.1 negative modulator of the initiation of chromosome replication YP_002262346.1 catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate YP_002262348.1 type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH YP_002262351.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol YP_002262352.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase YP_002262353.1 SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide YP_002262354.1 component of 2-oxoglutarate dehydrogenase complex; catalyzes the transfer of succinyl coenzyme A to form succinyl CoA as part of the conversion of 2-oxoglutarate to succinyl-CoA YP_002262355.1 catalyzes the interconversion of succinyl-CoA and succinate YP_002262356.1 Catalyzes the only substrate-level phosphorylation in the TCA cycle YP_002262358.1 Expression may be regulated by Fur YP_002262360.1 CDS contanins a rare Isoleucine start codon (ATA) YP_002262363.1 Expression may be stress-induced YP_002262364.1 responsible for the transport of C4-dicarboxylates during anaerobic growth YP_002262366.1 Similar to Vibrio vulnificus Hypothetical protein UniProt:Q8DAI1 (76 aa) fasta scores: E()=2e-12, 68.254% id in 63 aa overlap; query 1-63; subject 11-73. Expression may be stress-induced. The CDS may be truncated at the N-terminus YP_002262369.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate YP_002262370.1 Expression may be stress-induced YP_002262371.1 Expression may be stress-induced YP_002262373.1 Similar to Bacillus subtilis oligopeptide-binding protein AppA (PDB 1XOC). Evalue=4e-12, identity=(100, 479) YP_002262379.1 CDS is extended at the N-terminus in comparison to the Bacillus subtilis orthologue YP_002262382.1 Expression may be stress-induced YP_002262387.1 Expression may be regulated by Fur. No significant database matches YP_002262388.1 Expression may be regulated by Fur YP_002262389.1 Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1-phosphate YP_002262390.1 part of the metNIQ transport system for methionine YP_002262394.1 RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome YP_002262395.1 Expression may be regulated by Fur YP_002262396.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro) YP_002262400.1 Expression may be stress-induced. Probably regulator of genes involved in synthesis of phosphosugars YP_002262402.1 Expression may be regulated by Fur YP_002262410.1 Similar to Escherichia coli ATP-dependent helicase YoaA UniProt:P76257 (636 aa) fasta scores: E()=5.9e-163, 65.714% id in 630 aa YP_002262411.1 produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine YP_002262413.1 No significant database matches. Doubtful CDS, poor translational start site YP_002262420.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine YP_002262422.1 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not YP_002262423.1 Regulates rRNA biosynthesis by transcriptional antitermination YP_002262425.1 hydrolyzes phosphatidylglycerophosphate to produce phosphatidylglycerol and phosphate YP_002262426.1 The CDS appears to have a deletion of around 150 amino acid residues after codon 346 in comparison to the Vibrio cholerae orthologue YP_002262429.1 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate YP_002262431.1 catalyzes the bidirectional exonucleolytic cleavage of DNA YP_002262432.1 Homologous to MotA in E. coli and Salmonella. With PomB forms the ion channels that couple flagellar rotation to sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine. YP_002262433.1 with MotA forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; Vibrio parahaemolyticus protein is associated with the polar flagella YP_002262434.1 Required for the synthesis of the thiazole moiety YP_002262438.1 ketopantoate reductase; catalyzes the NADPH reduction of ketopantoate to pantoate; functions in pantothenate (vitamin B5) biosynthesis YP_002262442.1 Weakly similar to Escherichia coli.; rsmC; Ribosomal RNA small subunit methyltransferase C (P39406); length=342; id 28.620%; ungapped id 30.249%; E()=4.9e-13; 297 aa overlap; query 125-418; subject 57-340 YP_002262444.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm YP_002262445.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm YP_002262446.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm YP_002262447.1 Part of the NQR complex which catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm YP_002262448.1 Part of the NQR complex which consists of NqrA, NqrB, NqrC, NqrD, NqrE and NqrF; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm; NqrE is probably involved in the second step, the conversion of ubisemiquinone to ubiquinol. YP_002262449.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm YP_002262454.1 c.ahdi YP_002262459.1 Similar to Bacillus subtilis Tyrosine recombinase XerC UniProt:P39776 (304 aa) blastp scores: E()=3e-04. Lack of similarity at the N-terminus in comparison to other proteins YP_002262461.1 Weakly similar to Pseudomonas syringae pv. tomato site-specific recombinase, phage integrase family domain protein. UniProt:Q87W32 (EMBL:AE016853) (698 aa) fasta scores: E()=1e-14, 26.775% id in 676 aa. Lack of similarity at both the N- and C-terminus in comparison to the Pseudomonas syringae pv. tomato site-specific recombinase YP_002262464.1 Expression may be regulated by Fur YP_002262465.1 Expression may be regulated by Fur YP_002262466.1 catalyzes the conversion of guanine, xanthine and, to a lesser extent, hypoxanthine to GMP, XMP and IMP, respectively YP_002262467.1 forms a 1:1 complex with the unphosphorylated from of enzyme IIAGlc; FrsA may promote fermentation YP_002262468.1 catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis YP_002262469.1 Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway YP_002262470.1 catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group YP_002262471.1 lipoyl/octanoyltransferase; catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system H protein YP_002262477.1 SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA YP_002262479.1 required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA YP_002262480.1 Lack of similarity at the N-terminus in comparison to other proteins YP_002262481.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase YP_002262483.1 Transfers the fatty acyl group on membrane lipoproteins YP_002262487.1 catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A) YP_002262488.1 catalyzes the formation of 2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinol from 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol YP_002262493.1 Possible alternative translational start site after codon 17 YP_002262496.1 Possible alternative translational start site after codon 44 YP_002262497.1 Similar to Bacteriophage 186 Integrase Int UniProt:P06723 (336 aa) fasta scores: E()=2.6e-53, 45.190% id in 343 aa YP_002262498.1 Similar to Vibrio phage K139 glo glo. UniProt:Q37932 (EMBL:AF125163) (137 aa) fasta scores: E()=1.7e-06, 28.814% id in 118 aa, and to Vibrio phage K139 glo glo. UniProt:Q37932 (EMBL:AF125163) (137 aa) fasta scores: E()=1.7e-06, 28.814% id in 118 aa. Lack of similarity at the N- and C-terminus in comparison to Vibrio phage K139 glo YP_002262499.1 Similar to Vibrio phage K139 ci. UniProt:Q9XJF9 (EMBL:AF125163) (215 aa) fasta scores: E()=4.1e-21,47.257% id in 237 aa, and to Vibrio phage K139 ci. UniProt:Q9XJF9 (EMBL:AF125163) (215 aa) fasta scores: E()=4.1e-21, 47.257% id in 237 aa. Lack of similarity at the N-terminus in comparison to Vibrio phage K139 ci YP_002262500.1 Weakly similar to Haemophilus phage HP2 orf2(s)cox UniProt:Q775G1 (70 aa) blastp scores: E()=0.020 YP_002262504.1 Weakly similar to Vibrio phage K139 orf5. UniProt:Q8W764 (EMBL:AF125163) (104 aa) blastp scores: E()=5.4 YP_002262506.1 Weakly similar to Bacteriophage phi1026b gp41. UniProt:Q6JIJ0 (EMBL:AY453853) (85 aa) blastp scores: E()=0.22 YP_002262509.1 Similar to Bacteriophage 186 Replication gene A protein (gpa) UniProt:P41064 (694 aa) fasta scores: E()=1e-58, 36.631% id in 647 aa. Lack of similarity at the N-terminus in comparison to other proteins. CDS contains additional internal amino acids, residues 560 to 625, in comparison to Bacteriophage 186 YP_002262512.1 Expression may be Fur regulated YP_002262513.1 Similar to Vibrio phage K139 orf13 orf13. UniProt:Q8W755 (EMBL:AF125163) (83 aa) fasta scores: E()=5.2e-14, 56.098% id in 82 aa YP_002262514.1 Similar to Vibrio phage K139 orf15 UniProt:Q8W753 (348 aa) fasta scores: E()=1.2e-85, 66.372% id in 339 aa YP_002262515.1 Similar to Vibrio phage K139 orf16 UniProt:Q8W752 (605 aa) fasta scores: E()=3e-143, 66.612% id in 605 aa YP_002262516.1 Similar to Vibrio phage K139 orf17 UniProt:Q8W751 (299 aa) fasta scores: E()=4e-41, 49.020% id in 306 aa YP_002262517.1 Similar to Vibrio phage K139 orf18 UniProt:Q8W750 (341 aa) fasta scores: E()=2e-52, 48.000% id in 300 aa YP_002262518.1 Similar to Vibrio phage K139 orf19 UniProt:Q8W749 (238 aa) fasta scores: E()=2.7e-49, 51.464% id in 239 aa YP_002262520.1 Similar to Vibrio phage K139 orf20 UniProt:Q8W748 (153 aa) fasta scores: E()=2.5e-26, 51.299% id in 154 aa YP_002262521.1 Similar to Vibrio phage K139 orf21 UniProt:Q8W747 (162 aa) fasta scores: E()=1.2e-15, 33.974% id in 156 aa YP_002262522.1 Similar to Haemophilus phage HP2 orf23 UniProt:Q94MY9 (376 aa) fasta scores: E()=9.3e-68, 50.667% id in 375 aa YP_002262523.1 Similar to Vibrio phage K139 orf25 orf25. UniProt:Q8W743 (EMBL:AF125163) (152 aa) fasta scores: E()=8.2e-27, 55.782% id in 147 aa YP_002262524.1 Similar to Vibrio phage K139 orf26 orf26. UniProt:Q8W742 (EMBL:AF125163) (69 aa) fasta scores: E()=5.9e-09, 50.794% id in 63 aa YP_002262528.1 Similar to Haemophilus phage HP2 orf26. UniProt:Q775G2 (EMBL:AY027935) (102 aa) fasta scores: E()=4e-05, 32.927% id in 82 aa overlap; query 5-86; subject 21-102; phage protein YP_002262529.1 Similar to Vibrio phage K139 orf31 orf31. UniProt:Q8W737 (EMBL:AF125163) (605 aa) fasta scores: E()=3.2e-101, 55.500% id in 600 aa YP_002262530.1 Similar to Vibrio phage K139 orf32 orf32. UniProt:Q8W736 (EMBL:AF125163) (110 aa) fasta scores: E()=5.3e-13, 54.167% id in 96 aa YP_002262531.1 Similar to Vibrio phage K139 orf33 orf33. UniProt:Q8W735 (EMBL:AF125163) (399 aa) fasta scores: E()=1e-75, 51.139% id in 395 aa YP_002262532.1 Similar to Vibrio phage K139 orf34 orf34. UniProt:Q8W734 (EMBL:AF125163) (219 aa) fasta scores: E()=1.3e-35, 50.000% id in 184 aa YP_002262533.1 Similar to Bacteriophage HP1 tail fiber protein (orf31). UniProt:P51735 (EMBL:BH24159) (925 aa) fasta scores: E()=2.2e-35, 28.483% id in 646 aa YP_002262535.1 Similar to Vibrio phage K139 orf37. UniProt:Q8W731 (EMBL:AF125163) (297 aa) fasta scores: E()=1e-41, 41.497% id in 294 aa YP_002262536.1 Similar to Yersinia pseudotuberculosis hypothetical protein. UniProt:Q666T6 (EMBL:BX936398) (184 aa) fasta scores: E()=1.4e-14, 38.926% id in 149 aa; CDS is extended at the C-terminus in comparison to orthologues YP_002262537.1 Similar to Vibrio phage K139 orf39 orf39. UniProt:Q8W729 (EMBL:AF125163) (543 aa) fasta scores: E()=2.6e-82, 47.162% id in 458 aa YP_002262548.1 Expression may be stress-induced and regulated by Fur YP_002262552.1 works in conjunction with MinC and MinD to enable cell division at the midpoint of the long axis of the cell YP_002262554.1 blocks the formation of polar Z-ring septums YP_002262557.1 catalyzes the formation of 5-methylaminomethyl-2-thiouridine in position 34 of the anticodon of tRNA molecules YP_002262559.1 Expression may be stress-induced YP_002262560.1 catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde YP_002262562.1 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability YP_002262563.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits YP_002262567.1 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway YP_002262570.1 Possible alternative translational start site after codon 9 YP_002262571.1 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis YP_002262572.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA YP_002262574.1 involved in a recombinational process of DNA repair, independent of the recBC complex YP_002262577.1 dGTPase family type 2 subfamily; presumably hydrolyzes dGTP to deoxyguanosine and triphosphate YP_002262578.1 Expression may be regulated by Fur YP_002262583.1 broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor YP_002262584.1 Expression may be stress-induced YP_002262585.1 SEPHCHC synthase; forms 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1- carboxylate from 2-oxoglutarate and isochorismate in menaquinone biosynthesis YP_002262586.1 catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA YP_002262587.1 catalyzes the formation of 1,4-dihydroxy-2-naphthoate from O-succinylbenzoyl-CoA YP_002262588.1 catalyzes the dehydration of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid to form O-succinylbenzoate YP_002262592.1 Expression may be regulated by Fur YP_002262593.1 Similar to Pseudomonas aeruginosa Serine/threonine phosphoprotein phosphatase Stp1 UniProt:Q9I355 (242 aa) fasta scores: E()=6.2e-18, 36.283% id in 226 aa. The CDS appears to have a 16 amino acid residue deletion after codon 133 compared with Pseudomonas aeruginosa Stp1 YP_002262599.1 Possible alternative translational start site 99 nucleotides upstream present start YP_002262604.1 Weakly similar to Vibrio cholerae vasJ. Expression may be regulated by Fur YP_002262608.1 helicase involved in DNA repair and perhaps also replication YP_002262611.1 long form of enzyme; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms active dimers and inactive hexamers which is dependent on concentration of substrates and inhibitors YP_002262612.1 catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer YP_002262613.1 catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis YP_002262614.1 catalyzes the formation of 3-(imidazol-4-yl)-2-oxopropyl phosphate from D-ethythro-1-(imidazol-4-yl)glycerol 3-phosphate and histidinol from histidinol phosphate YP_002262615.1 with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide YP_002262616.1 catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide YP_002262617.1 catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase YP_002262618.1 catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribosyl)-ATP and the subsequent formation of 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide from 1-(5-phosphoribosyl)-AMP in histidine biosynthesis YP_002262623.1 unknown function; YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the predicted reactions based on sequence and structure similarity YP_002262625.1 Involved in cell division; probably involved in intracellular septation YP_002262626.1 catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis YP_002262627.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate YP_002262628.1 monomeric bifunctional protein; functions in tryptophan biosynthesis pathway; phosphoribosylanthranilate is rearranged to carboxyphenylaminodeoxyribulosephosphate which is then closed to form indole-3-glycerol phosphate YP_002262629.1 Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate YP_002262630.1 TrpG; with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine; TrpG provides the glutamine amidotransferase activity YP_002262631.1 with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine YP_002262637.1 Expression may be regulated by Fur YP_002262638.1 SohB; periplasmic protein; member of the peptidase S49 family YP_002262641.1 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity YP_002262644.1 Weakly similar to Rhizobium leguminosarum bv. trifolii ImpA UniProt:Q93ED3 (358 aa) fasta scores: E()=0.0033, 23.618% id in 398 aa. Operon structure similar to Rhizobium leguminosarum bv. trifolii operon harbouring temperature-dependent protein secretion proteins. Expression may be regulated by Fur YP_002262646.1 Operon structure similar to Rhizobium leguminosarum bv. trifolii operon harbouring temperature-dependent protein secretion proteins YP_002262647.1 Operon structure similar to Rhizobium leguminosarum bv. trifolii operon harbouring temperature-dependent protein secretion proteins YP_002262648.1 Operon structure similar to Rhizobium leguminosarum bv. trifolii operon harbouring temperature-dependent protein secretion proteins YP_002262650.1 Operon structure similar to Rhizobium leguminosarum bv. trifolii operon harbouring temperature-dependent protein secretion proteins YP_002262654.1 Contains phospho-specific protein-protein interaction motif FHA YP_002262656.1 Operon structure similar to Rhizobium leguminosarum bv. trifolii operon harbouring temperature-dependent protein secretion proteins YP_002262659.1 Serine/Threonine protein kinase domain YP_002262661.1 Expression may be regulated by Fur YP_002262667.1 catalyzes the release of the N-terminal amino acid from a tripeptide YP_002262670.1 Similar to Escherichia coli HTH-type transcriptional regulator CynR (cyn operon transcriptiona activator) UniProt:P27111 (299 aa) blastp scores: E()=1e-10 YP_002262676.1 Expression may be stress-induced YP_002262678.1 C-terminal part is similar to Vibrio cholerae Lysophospholipase L2 LypA UniProt:Q56636 (338 aa) fasta scores: E()=1.5e-40, 38.554% id in 332 aa, and N-terminal part is similar to Escherichia coli Hypothetical protein UniProt:Q2M5U0 (357 aa) fasta scores: E()=4.4e-40, 38.170% id in 317 aa. From sequence comparisons the CDS appears as a fusion of two genes. The sequence has been checked and is believed to be correct YP_002262683.1 Expression may be stress-induced YP_002262687.1 Similar to Pseudomonas aeruginosa mobile metallo-beta-lactamase blaGIM-1 UniProt:Q704V1 (250 aa) fasta scores: E()=1.1e-33, 40.833% id in 240 aa YP_002262693.1 CDS is extended at the N-terminus in comparison to orthologues YP_002262698.1 Expression may be regulated by Fur YP_002262699.1 functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to dcuB YP_002262718.1 Expression may be regulated by Fur YP_002262719.1 Expression may be regulated by Fur YP_002262721.1 Possible alternative translational start site after codon 5 YP_002262722.1 Similar to Escherichia coli Glycine cleavage system transcriptional activator GcvA UniProt:P0A9F6 (305 aa) fasta scores: E()=2.4e-19, 32.013% id in 303 aa YP_002262724.1 Similar to Marinococcus halophilus Ectoine transporter EctM UniProt:Q6VTH4 (525 aa) fasta scores: E()=5e-45, 27.733% id in 494 aa YP_002262729.1 catalyzes the cleavage of the lactyl ether moiety of N-acetylmuramic acid-6-phosphate (MurNAc-6-P) to form N-acetylglucosamine-6-phosphate (GlcNAc-6-P) and lactate; involved in MurNAc dissimilation pathway YP_002262735.1 Similar to Thermotoga maritima ribonucleotide reductase (B12-dependent) PDB 1XJE, Evalue 9e-56 YP_002262736.1 Similar to caulobacter crescentus (caulobacter vibrioides) Response regulator PleD UniProt:Q9A5I5 (454 aa) fasta scores: E()=4.5e-16, 31.447% id in 318 aa YP_002262739.1 malic enzyme; oxaloacetate-decarboxylating; NAD-dependent; catalyzes the formation of pyruvate form malate YP_002262745.1 Similar to bacillus subtilis Glycine betaine transporter OpuD UniProt:P54417 (512 aa) fasta scores: E()=4.2e-61, 38.763% id in 485 aa YP_002262777.1 unknown function; when overproduced it confers drug-resistance YP_002262778.1 Probably regulates genes involved in cell wall metabolism and genes involved in virulence YP_002262781.1 metalloprotease YP_002262783.1 Expression may be regulated by Fur YP_002262784.1 Expression may be regulated by Fur YP_002262785.1 Similar to Pseudomonas sp. Atrazine chlorohydrolase AtzA UniProt:P72156 (474 aa) blastp scores: E()=7e-45 YP_002262788.1 catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_002262791.1 with SbcC cleaves DNA hairpin structure, also has 5' single-strand endonuclease activity YP_002262800.1 Expression may be regulated by Fur YP_002262808.1 Similar to Pseudomonas aeruginosa Multidrug resistance protein MexA precursor UniProt:P52477 (383 aa) blastp scores: E()=9e-17 YP_002262809.1 Similar to Pseudomonas putida Solvent efflux pump periplasmic linker SrpA precursor UniProt:O31099 (382 aa) fasta scores: E()=9.6e-13, 26.829% id in 369 aa YP_002262810.1 Similar to Ralstonia metallidurans Cobalt-zinc-cadmium resistance protein CzcA UniProt:P13511 (1063 aa) blastp scores: E()=2e-66 YP_002262812.1 catalyzes the formation of L-homocysteine from cystathionine YP_002262819.1 CDS may be truncated by the insertion of the downstream IS element and subsequent recombination events; Similar to Aeromonas hydrophila Nuclease NucH UniProt:Q44070 (1070 aa) fasta scores: E()=1.7e-38,38.610% id in 878 aa. CDS is slightly extended at the N-terminus in comparison to orthologues. Probably due to the insertion of the downstream IS element YP_002262821.1 catalyzes the formation of a phosphodiester at the site of a single-strand break in duplex DNA YP_002262823.1 catalyzes the formation of D-ribose 5-phosphate from ribose YP_002262824.1 periplasmic substrate-binding component of the ATP-dependent ribose transport system YP_002262825.1 functions to transport ribose at high affinity; forms a complex with RbsA2C2B YP_002262826.1 with RbsBCD acts to import ribose into the cell; RbsA contains 2 ATP-binding protein YP_002262827.1 cytoplasmic mutarotase that catalyzes the conversion between beta-pyran and beta-furan forms of D-ribose; RbsD is required for efficient ribose utilization in E. coli; rbsD-mutant E. coli strains are unable to use ribose as a sole carbon source YP_002262830.1 Expression may be regulated by Fur YP_002262831.1 Similar to C-terminal part of Vibrio fischeri Ferrichrome-binding protein. UniProt:Q5E573 (178 aa) blastp scores: E()=8e-04 YP_002262836.1 NorM; MdtK; functions as a Na(+)/drug antiporter; inactivation in Vibrio cholerae results in susceptibility to fluoroquinolones YP_002262837.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine YP_002262841.1 Similar to Escherichia coli Lipoprotein Spr UniProt:P0AFV4 (188 aa) fasta scores: E()=4.6e-19, 50.000% id in 112 aa YP_002262846.1 catalyzes the formation of N-acetyl-D-glucosamine-6-phosphate from N-acetyl-D-glucosamine YP_002262851.1 CDS is extended with approximately 180 aa residues at the N-terminus in comparison to the Escherichia coli orthologue YP_002262852.1 in Escherichia coli MobA links a guanosine 5'-phosphate to molydopterin to form molybdopterin guanine dinucleotide during molybdenum cofactor biosynthesis YP_002262853.1 Similar to Escherichia coli Glutamine transport ATP-binding protein GlnQ UniProt:P10346 (240 aa) blastp scores: E()=1e-18 YP_002262855.1 Similar to Eubacterium acidaminophilum Extracellular tungstate binding protein precursor TupA UniProt:Q93KD6 (286 aa) fasta scores: E()=1e-41, 49.796% id in 245 aa YP_002262856.1 Similar to Escherichia coli Signal transduction histidine-protein kinase AtoS UniProt:Q06067 (608 aa) fasta scores: E()=1e-20, 34.333% id in 300 aa YP_002262872.1 Similar to Escherichia coli 3-mercaptopyruvate sulfurtransferase SseA UniProt:P31142 (280 aa) fasta scores: E()=5.9e-30, 35.507% id in 276 aa YP_002262877.1 No significant database matches. Expression may be regulated by Fur YP_002262885.1 Similar to Bacillus subtilis Kinase A inhibitor KipI UniProt:P60495 (240 aa) fasta scores: E()=2.1e-23,34.361% id in 227 aa YP_002262890.1 Similar to Escherichia coli Manganese transport protein MntH UniProt:P0A769 (412 aa) fasta scores: E()=1.8e-05, 21.792% id in 413 aa YP_002262893.1 Possible alternative translational start site after codon 11 YP_002262896.1 Expression may be regulated by Fur YP_002262901.1 Similar to Escherichia coli Formate dehydrogenase,nitrate-inducible, cytochrome b556(fdn) subunit FdnI UniProt:P0AEK7 (217 aa) fasta scores: E()=1.7e-14, 28.899% id in 218 aa YP_002262910.1 Similar to Vibrio cholerae Hypothetical protein UniProt:Q9KMD9 (97 aa) fasta scores: E()=8.2e-11, 79.310% id in 58 aa. CDS is extended at the N-terminus in comparison to orthologues YP_002262913.1 Similar to Rhizobium leguminosarum bv. trifolii Trifolitoxin immunity protein TfxG UniProt:P42729 (261 aa) fasta scores: E()=1.9e-12, 35.961% id in 203 aa. Expression may be regulated by Fur YP_002262916.1 CDS contanins a rare Leucine start codon (TTA). No significant database matches YP_002262923.1 Similar to Chlamydia trachomatis 3-oxoacyl-[acyl-carrier-protein] reductase FabG UniProt:P38004 (247 aa) fasta scores: E()=1.4e-15, 34.146% id in 205 aa YP_002262933.1 Weakly similar to Myxococcus xanthus CsgA UniProt:P21158 blastp scores: E()=4e-09 YP_002262945.1 Similar to Mentha piperita (peppermint) Omt5 UniProt:Q6VMV7 (361 aa) blastp scores: E()=6e-05 YP_002262952.1 Similar to Pseudomonas aeruginosa HTH-type transcriptional regulator TrpI UniProt:P11720 (295 aa) fasta scores: E()=7.8e-16, 29.010% id in 293 aa YP_002262953.1 Similar to Pseudomonas aeruginosa Multidrug resistance protein PmpM UniProt:Q9I3Y3 (477 aa) fasta scores: E()=1.3e-20, 27.887% id in 459 aa YP_002262959.1 Similar to Escherichia coli KefA UniProt:P77338 (1120 aa) blastp scores: E()=4e-12 YP_002262966.1 Similar to Pseudomonas sp. Atrazine chlorohydrolase AtzA UniProt:P72156 (474 aa) fasta scores: E()=2.8e-21,27.500% id in 440 aa YP_002262968.1 Similar to Pseudomonas aeruginosa Cyclohexadienyl dehydratase precursor PheC UniProt:Q01269 (268 aa) fasta scores: E()=3.7e-25, 39.910% id in 223 aa YP_002262970.1 Stimulates the peptidyltransferase activity of the 70S ribosome and enhances dipeptide synthesis with N-formylmethionyl-tRNA and puromycin in vitro, suggesting its involvement in the formation of the first peptide bond of a protein YP_002262972.1 in Escherichia coli this enzyme specifically methylates C1407 of the 16S rRNA YP_002262975.1 Similar to Escherichia coli Lipid A export ATP-binding/permease protein MsbA UniProt:P60752 (582 aa) blastp scores: E()=2e-61. Expression may be regulated by Fur YP_002262976.1 Expression may be regulated by Fur YP_002262977.1 affects solute and DNA transport through an unknown mechanism YP_002262978.1 Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3 YP_002262981.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors YP_002262982.1 Possible alternative translational start site after codon 17 YP_002262983.1 catalyzes the N2-methyl guanosine modification of the G2445 residue of 23S rRNA YP_002262985.1 Uup; in Escherichia coli this cytoplasmic protein was shown to contain ATPase activity; mutations in this gene affect RecA-independent excision of transposons and affects Mu bacteriophage growth YP_002262988.1 catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to 2,3-decenoyl-ACP or 3,4-decenoyl-ACP YP_002262989.1 Similar to Escherichia coli protease La homolog YcbZ UniProt:P75867 (586 aa) fasta scores: E()=6.7e-67, 41.525% id in 472 aa YP_002262995.1 CcoN; FixN YP_002262996.1 CcoO; FixO YP_002263000.1 Similar to Bradyrhizobium japonicum Nitrogen fixation protein FixI UniProt:Q59207 (730 aa) fasta scores: E()=9.9e-70, 33.884% id in 726 aa YP_002263001.1 Similar to Rhizobium meliloti Nitrogen fixation protein FixS UniProt:P18399 (55 aa) blastp scores: E()=6e-04 YP_002263003.1 Global transcription factor that controls the expression of over 100 target genes in response to anoxia YP_002263004.1 with UspC and UspD is involved in resistance to UV irradiation YP_002263005.1 TtcA; YdaO; catalyzes the thiolation of cytosine 32 in specific tRNAs YP_002263012.1 functions together with PotBCD (A2BCD) in ATP-dependent polyamine transport; PotA is the membrane-associated ATPase YP_002263013.1 can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotB is a membrane component YP_002263014.1 can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotC is a membrane component YP_002263015.1 Possible alternative translational start site after codon 13 YP_002263016.1 Expression may be stress-induced YP_002263017.1 Modulates the activities of several enzymes which are inactive in their acetylated form YP_002263019.1 Similar to Escherichia coli inner membrane transport protein YeiJ UniProt:P33021 (416 aa) fasta scores: E()=8.5e-59, 43.301% id in 418 aa YP_002263029.1 Possible alternative translational start site after codon 10 YP_002263038.1 Expression may be regulated by Fur YP_002263039.1 Similar to Bacillus subtilis Malate-2H(+)/Na(+)-lactate antiporter MleN UniProt:P54571 (468 aa) fasta scores: E()=3.1e-28, 33.772% id in 456 aa YP_002263045.1 phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS); catalyzes the phosphorylation of maltose and glucose concomitant with their translocation across the cell membrane; component IIB catalyzes the phosphorylation of the sugar molecule; IIC forms the translocation channel and contains the substrate specific binding site YP_002263048.1 regulates malXY which are involved in maltose-glucose transport YP_002263063.1 phosphorylates methylthioribose to form methylthioribose-1-phosphate; involved in methionine salvage pathway YP_002263064.1 Weakly similar to Vibrio cholerae TcpI UniProt:P29486 (620 aa) fasta scores: E()=1.1e-28, 33.588% id in 393 aa YP_002263078.1 Doubtful CDS, poor translational start site YP_002263084.1 Similar to Elizabethkingia miricola n(4)-(beta-n-acetylglucosaminyl)-l-asparaginase precursor UniProt:Q47898 (340 aa) fasta scores: E()=7.5e-31, 37.050% id in 278 aa YP_002263094.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria YP_002263101.1 porin involved in osmoregulation allowing water to move into and out of the cell in response to osmotic pressure YP_002263104.1 Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates YP_002263105.1 Similar to Escherichia coli membrane protein YohJ UniProt:P60632 (132 aa) fasta scores: E()=3e-11, 44.211% id in 95 aa YP_002263107.1 Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis YP_002263109.1 non-folate utilizing enzyme, catalyzes the production of beta-formyl glycinamide ribonucleotide from formate, ATP, and beta-GAR and a side reaction producing acetyl phosphate and ADP from acetate and ATP; involved in de novo purine biosynthesis YP_002263110.1 catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate YP_002263112.1 LysR-type transcriptional regulator; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates cysteine biosynthesis by controlling expression of the cys regulon; autoregulates expression; crystal structure of Klebsiella aerogenes showed tetramer formation YP_002263116.1 Expression may be regulated by Fur YP_002263120.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase YP_002263121.1 Possible alternative translational start site after codon 20 YP_002263122.1 involved in the post-transcriptional processing of the daa operon mRNA, which encodes proteins involved in fimbrial biogenesis of an enteropathogenic E. coli strain YP_002263123.1 Similar to Vibrio cholerae outer membrane porin OmpA UniProt:O31154 (321 aa) fasta scores: E()=3e-19, 33.225% id in 307 aa YP_002263126.1 catalyzes the hydrolysis of acylphosphate YP_002263130.1 hydrolyzes deacylated phospholipids to glycerol 3-phosphate and the corresponding alcohols; periplasmic YP_002263131.1 catalyzes the uptake of glycerol-3-phosphate into the cell with the simultaneous export of inorganic phosphate from the cell YP_002263140.1 Similar to Escherichia coli Phosphoenolpyruvate synthase PpsA UniProt:P23538 (791 aa) fasta scores: E()=3.5e-21, 33.898% id in 236 aa YP_002263141.1 tryptophan sensitive; catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate YP_002263142.1 nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ; the YajQ protein from Pseudomonas synringae appears to play a role in activation of bateriophage phi6 segment L transcription YP_002263144.1 catalyzes the formation of succinate and glutamate from N(2)-succinylglutamate in arginine catabolism YP_002263145.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control YP_002263146.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily YP_002263147.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily YP_002263159.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III YP_002263164.1 with HmuTU is involved in the transport of hemin YP_002263165.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit YP_002263167.1 CDS contanins a rare Isoleucine start codon (ATT) YP_002263168.1 catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_002263169.1 Similar to Bacillus subtilis Spo0M UniProt:O87735 (258 aa) fasta scores: E()=5.5e-16, 38.117% id in 223 aa YP_002263172.1 Similar to Escherichia coli YegD UniProt:P36928 (450 aa) fasta scores: E()=9.3e-90, 55.679% id in 449 aa YP_002263176.1 Involved in ubiquinone biosynthesis YP_002263177.1 Catalyzes the rate-limiting step in dNTP synthesis YP_002263178.1 B2 or R2 protein; type 1a enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdA YP_002263192.1 Expression may be regulated by Fur YP_002263193.1 catalyzes the conversion of GTP to formate and 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and diphosphate YP_002263196.1 Similar to Pasteurella haemolytica (mannheimia haemolytica) HsdR UniProt:P95512 (1055 aa) fasta scores: E()=2.8e-27, 27.793% id in 1083 aa YP_002263197.1 Similar to Salmonella enterica HsdM UniProt:P72418 (539 aa) fasta scores: E()=2.4e-42, 33.469% id in 493 aa YP_002263201.1 Similar to Escherichia coli small-conductance mechanosensitive channel MscS UniProt:P0C0S1 (286 aa) fasta scores: E()=1.6e-27, 34.643% id in 280 aa YP_002263204.1 Similar to Thermus aquaticus thermostable carboxypeptidase 1 UniProt:P42663 (511 aa) fasta scores: E()=2.4e-53, 36.853% id in 502 aa YP_002263215.1 Similar to Escherichia coli Hypothetical symporter YdjN UniProt:P77529 (463 aa) fasta scores: E()=2.2e-84,59.161% id in 453 aa YP_002263216.1 catalyzes the S-adenosylmethionine-dependent transmethylation of thiopurine compounds; may be involved in selenium cycling by forming dimethylselenide and/or dimethyldiselenide YP_002263217.1 Similar to Streptococcus pneumoniae CTP:phosphocholine Cytidylytransferase (PDB 1JYK),evalue=3e-18 YP_002263219.1 Similar to Salmonella typhimurium 2-aminoethylphosphonate-pyruvate aminotransferase (PDB 1M32), evalue=5e-33, identity=(110, 360) YP_002263220.1 Similar to Enterobacter sakazakii OmpA UniProt:Q52JK5 (347 aa) fasta scores: E()=3.7e-32, 32.286% id in 350 aa YP_002263222.1 Possible alternative translational start site after codon 8 YP_002263225.1 Similar to Escherichia coli Chaperone protein DnaK UniProt:P0A6Y8 (637 aa) fasta scores: E()=6.8e-06, 23.077% id in 429 aa YP_002263226.1 Similar to Methylovorus sp. Chaperone protein DnaK UniProt:Q9ZFC6 (641 aa) fasta scores: E()=1.7e-06, 25.056% id in 443 aa YP_002263230.1 catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate; involved in the pyrimidine salvage pathway YP_002263232.1 in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c YP_002263233.1 in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c YP_002263236.1 mediates a global response to leucine; acts as a regulator for several genes involved in the high-affinity branched-chain amino acid transport system YP_002263238.1 participates with LolB in the incorporation of lipoprotein into the outer membrane YP_002263240.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_002263242.1 highly acidic protein; the structure of the Haemophilus influenzae protein shows similarity to uracil DNA glycosylase inhibitor (Ugi); binds heat-unstable protein (HU-alpha) which is a histone-like protein YP_002263245.1 Expression may be regulated by Fur YP_002263246.1 this stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress YP_002263248.1 Expression may be stress-induced YP_002263255.1 Similar to Escherichia coli YdhD UniProt:P0AC69 (115 aa) fasta scores: E()=1.3e-31, 72.321% id in 112 aa YP_002263256.1 Similar to Vibrio cholerae VieB UniProt:O68319 (553 aa) fasta scores: E()=5.3e-07, 23.249% id in 357 aa YP_002263258.1 Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A) YP_002263260.1 Expression may be regulated by Fur YP_002263263.1 in Excherichia coli RsxABCDEG reduces SoxR which turns off induction of SoxS transcription factor in the absence of oxidizing agents; similar to the rnfABCDGE operon in Rhodobacter capsulatus involved in transferring electrons to nitrogenase YP_002263264.1 part of membrane-bound complex hought to be involved in electron transport to nitrogen YP_002263266.1 part of membrane-bound complex thought to be involved in electron transport to nitrogen YP_002263267.1 part of membrane-bound complex thought to be involved in electron transport to nitrogen YP_002263269.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion YP_002263273.1 together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z YP_002263274.1 MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis YP_002263275.1 catalyzes the conversion of molybdopterin precursor Z into molybdopterin YP_002263279.1 Expression may be stress-induced YP_002263282.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes YP_002263283.1 endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity YP_002263284.1 plays an essential role in ATP-dependent branch migration of the Holliday junction YP_002263285.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration YP_002263294.1 forms dimers; may be involved in cell envelope integrity; interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA YP_002263297.1 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate YP_002263309.1 Similar to Escherichia coli GTP-binding protein HflX UniProt:P25519 (426 aa) fasta scores: E()=7e-30,33.484% id in 442 aa YP_002263313.1 Similar to Escherichia coli MFS-type transporter protein ycaD UniProt:P21503 (382 aa) fasta scores: E()=2e-27, 32.275% id in 378 aa YP_002263315.1 Expression may be regulated by Fur YP_002263316.1 Expression may be regulated by Fur YP_002263318.1 Expression may be regulated by Fur YP_002263319.1 Similar to Escherichia coli Immunoglobulin-binding regulator IbrB UniProt:Q8KU23 (214 aa) fasta scores: E()=4.1e-17, 33.649% id in 211 aa YP_002263323.1 ATP-dependent adenylate transferase, transfers adenyl moiety to the MoeD subunit of molybdopterin synthase YP_002263325.1 involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer YP_002263326.1 catalyzes the transfer of a phosphatidyl group to phosphodidylglycerol to form cardiolipin (diphosphatidylglycerol) YP_002263330.1 catalyzes the formation of 2,3=diacylglucosamine 1-phosphate from UDP-2,3=diacylglucosamine YP_002263332.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA YP_002263333.1 catalyzes the formation of thymidine 5'-phosphate from thymidine YP_002263340.1 Possible alternative translational start site after codon 9 YP_002263342.1 activates pyruvate formate-lyase 1 under anaerobic conditions YP_002263345.1 Similar to Escherichia coli formate transporter 1 FocA UniProt:P0AC23 (285 aa) fasta scores: E()=2.7e-69, 63.380% id in 284 aa YP_002263350.1 cofactor involved in the reduction of disulfides YP_002263351.1 removes the damaged DNA at cytosines and guanines by cleaving on the 3' side of the AP site by a beta-elimination reaction YP_002263353.1 YbaX; catalyzes the transformation of GTP to 7-cyano-7-deazaguanine (preQ0), as one of the early reactions of quenosine biosynthesis; quenosine is a modified nucleoside that occurs at the wobble position of GUN anticodons in tRNAs for Asn, Asp, Tyr, and His YP_002263355.1 Similar to Zymomonas mobilis Glutamate uptake regulatory protein UniProt:P74996 (164 aa) fasta scores: E()=3.8e-21, 44.371% id in 151 aa YP_002263360.1 Similar to Escherichia coli Iron transport protein, periplasmic binding protein SitA UniProt:Q2L3R1 (304 aa) fasta scores: E()=1.8e-29, 32.993% id in 294 aa YP_002263361.1 Similar to Yersinia pestis Chelated iron transport system membrane protein yfeD UniProt:Q56955 (297 aa) fasta scores: E()=1.2e-19, 28.625% id in 269 aa YP_002263362.1 Similar to Escherichia coli Iron(III) dicitrate transport ATP-binding protein fecE UniProt:P15031 (255 aa) blastp scores: E()=3e-30 YP_002263370.1 Similar to Haemophilus influenzae DNA transformation protein TfoX UniProt:P43779 fasta scores: E()=2e-07, 28.718% id in 195 aa YP_002263372.1 TorD; involved in the biogenesis of torA; acts on torA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor YP_002263373.1 response regulator in two-component regulatory system with TorS; involved in regulation of trimethylamine N-oxide reductase genes YP_002263381.1 Similar to Proteus vulgaris Phospholipase A1 precursor PldA UniProt:P37447 (289 aa) fasta scores: E()=2.6e-30, 39.574% id in 235 aa YP_002263382.1 Similar to Escherichia coli Formate-dependent nitrite reductase complex NrfG subunit UniProt:P32712 (198 aa) fasta scores: E()=4.5e-12, 32.812% id in 192 aa YP_002263383.1 catalyzes the formate-dependent reduction of nitrite to ammonia; cytochrome C552 YP_002263384.1 part of nitrite reductase complex; NrfB is active at high nitrate conditions; NrfA, B, C, and D are essential for the formate-dependent nitrite reduction to ammonia YP_002263388.1 Similar to Escherichia coli Thiol:disulfide interchange protein dsbE UniProt:P0AA86 (185 aa) fasta scores: E()=1.3e-20, 37.805% id in 164 aa YP_002263389.1 Similar to Escherichia coli Formate-dependent nitrite reductase complex nrfF subunit precursor UniProt:P32711 (127 aa) fasta scores: E()=1.4e-16, 50.505% id in 99 aa YP_002263391.1 functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to dcuB YP_002263392.1 Expression may be regulated by Fur YP_002263393.1 Similar to Escherichia coli Phosphatidylglycerophosphatase B PgpB UniProt:P0A924 (254 aa) fasta scores: E()=1e-09, 30.270% id in 185 aa YP_002263399.1 Involved in sulfonamide (sulfathiazole) and bicyclomycin resistance YP_002263401.1 Expression may be regulated by Fur YP_002263402.1 Similar to Agrobacterium tumefaciens AttE UniProt:O32734 (264 aa) fasta scores: E()=2.7e-30, 48.387% id in 217 aa. May be required for virulence and attachment to host cells YP_002263403.1 Similar to C-terminal part of Agrobacterium tumefaciens AttG UniProt:Q79C15 (415 aa) fasta scores: E()=1.3e-25, 27.654% id in 405 aa. May be required for virulence and attachment to host cells YP_002263404.1 Similar to Agrobacterium tumefaciens AttH UniProt:O32737 (355 aa) fasta scores: E()=9.9e-42, 33.841% id in 328 aa. May be required for virulence and attachment to host cells YP_002263405.1 exports sodium by using the electrochemical proton gradient to allow protons into the cell; functions in adaptation to high salinity and alkaline pH; activity increases at higher pH; downregulated at acidic pH YP_002263407.1 enzyme from Treponema denticola exhibits NADH-dependent trans-2-enoyl-CoA reductase activity YP_002263409.1 functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase; also involved in reducing some disulfides in a coupled system with glutathione reductase YP_002263410.1 Represses the expression of the zwf, eda, glp and gap YP_002263411.1 Similar to Haemophilus influenzae L-2,4-diaminobutyrate decarboxylase ddc UniProt:P71362 (511 aa) fasta scores: E()=5e-24, 26.609% id in 466 aa YP_002263413.1 Lack of similarity at the C-terminus in comparison to other proteins YP_002263419.1 catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine YP_002263429.1 Similar to Escherichia coli Inner membrane protein yccA UniProt:P0AAC6 (219 aa) fasta scores: E()=1.5e-36, 61.009% id in 218 aa YP_002263442.1 Similar to Bacillus halodurans Reverse transcriptase-maturase-endonuclease UniProt:Q9JWR9 (418 aa) fasta scores: E()=1.9e-39, 34.314% id in 408 aa YP_002263443.1 P-type ATPase involved in the export of lead, cadmium, zinc and mercury YP_002263449.1 Similar to Escherichia coli Chloramphenicol acetyltransferase 3 UniProt:P00484 (213 aa) fasta scores: E()=6.6e-13, 26.415% id in 212 aa YP_002263453.1 catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine YP_002263454.1 Catalyzes the transfer of the ammonia group from glutamine to a new carbon-nitrogen group YP_002263456.1 Similar to Neisseria gonorrhoeae Phospholipase D (Fragment) UniProt:Q6W764 (525 aa) fasta scores: E()=1.9e-53, 36.031% id in 519 aa YP_002263459.1 the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response YP_002263463.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis YP_002263465.1 FabB; beta-ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP YP_002263469.1 Similar to Pseudomonas sp. 4-hydroxybenzoyl CoA thioesterase (PDB 1LO8), evalue=2e-05 identity=(29, 104) YP_002263470.1 Similar to Homo sapiens Histidine ammonia-lyase UniProt:P42357 (657 aa) fasta scores: E()=2.2e-52, 33.594% id in 512 aa YP_002263473.1 Similar to Bacillus brevis Gramicidin synthease 1 (PDB 1AMU), evalue=1e-06 identity=(38, 136) YP_002263475.1 carries the fatty acid chain in fatty acid biosynthesis YP_002263480.1 Similar to Streptomyces glaucescens Multifunctional cyclase-dehydratase-3-O-methyl transferase tcmN UniProt:P16559 (494 aa) fasta scores: E()=1.3e-05, 23.934% id in 305 aa YP_002263483.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase YP_002263484.1 Expression may be stress-induced YP_002263485.1 AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA YP_002263486.1 catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate YP_002263490.1 Expression may be regulated by Fur YP_002263491.1 Similar to Streptococcus pneumoniae Transmembrane protein PstC UniProt:Q9X4T1 (271 aa) fasta scores: E()=2.7e-34, 46.840% id in 269 aa YP_002263492.1 Similar to Streptococcus pneumoniae Phosphate ABC transporter PstA UniProt:Q9X4T2 (271 aa) fasta scores: E()=5.8e-37, 47.566% id in 267 aa YP_002263493.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation YP_002263500.1 Similar to Pseudomonas aeruginosa Chemotactic transducer PctB UniProt:O32443 (629 aa) fasta scores: E()=1e-36, 38.950% id in 362 aa YP_002263502.1 periplasmic sensory protein associated with the TorRS two-component regulatory system YP_002263503.1 catalyzes the formation of methylglyoxal from glycerone phosphate YP_002263504.1 catalyzes the ATP-dependent unwinding of duplex DNA in the 3' to 5' direction with respect to the bound single strand YP_002263505.1 Similar to Escherichia coli Inner membrane protein YccS UniProt:P75870 (717 aa) fasta scores: E()=8.4e-107, 43.115% id in 719 aa. Possible alternative translational start site after codon 10 YP_002263506.1 Possible alternative translational start site after codon 4 YP_002263508.1 Similar to N-terminal part of Rhizobium meliloti Diaminobutyrate--2-oxoglutarate aminotransferase RhbA UniProt:Q9Z3R2 (470 aa) fasta scores: E()=3.9e-85, 51.306% id in 421 aa, which is involved in siderophore biosynthesis YP_002263510.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision YP_002263511.1 in Escherichia coli the protein UvrY is part of a two-component system along with BarA that is needed for efficient switching between glycolytic and gluconeogenic carbon sources possibly by regulating the Csr system; in Salmonella SirA and BarA regulate virulence gene expression also via the Csr system YP_002263512.1 Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C YP_002263514.1 Similar to Bacillus subtilis Malate-2H(+)/Na(+)-lactate antiporter MleN UniProt:P54571 (468 aa) fasta scores: E()=2.6e-06, 31.034% id in 174 aa. Expression may be regulated by Fur YP_002263516.1 Similar to Escherichia coli MltA-interacting protein precursor MipA UniProt:P0A908 (248 aa) fasta scores: E()=4.3e-20, 29.876% id in 241 aa YP_002263517.1 Multifunctional regulator of fatty acid metabolism YP_002263518.1 involved in regulation of intracellular pH under alkaline conditions YP_002263519.1 disulfide oxidoreductase; integral membrane protein; required for perioplasmic disulfide bond formation; oxidizes DsbA protein YP_002263521.1 Similar to Vibrio cholerae Immature fimbrillin precursor FimA UniProt:Q79F49 (175 aa) fasta scores: E()=9.3e-08, 31.548% id in 168 aa YP_002263524.1 Expression may be stress-induced YP_002263525.1 decatenates replicating daughter chromosomes YP_002263528.1 converts asparagine to aspartate and ammonia YP_002263529.1 catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde YP_002263533.1 Expression may be stress-induced YP_002263535.1 involved in methylation of ribosomal protein L3 YP_002263536.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis YP_002263537.1 Similar to Escherichia coli inner membrane protein YicG UniProt:P0AGM3 (205 aa) fasta scores: E()=6.1e-41, 58.794% id in 199 aa YP_002263538.1 Similar to Salmonella typhimurium Mg(2+) transport ATPase protein C MgtC UniProt:P22037 (231 aa) fasta scores: E()=2.4e-08, 34.921% id in 126 aa YP_002263543.1 Transfers myristate or laurate, activated on ACP, to the lipid IVA moiety of (KDO)2-(lauroyl)-lipid IVA YP_002263544.1 Acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation YP_002263548.1 methylates the guanosine in position 745 of 23S rRNA; required for translation and cell growth YP_002263549.1 Similar to Enterobacter cloacae Outer membrane pore protein E precursor PhoE UniProt:Q47490 (350 aa) fasta scores: E()=4.6e-11, 28.460% id in 383 aa YP_002263551.1 catalyzes the formation of 10-formyltetrahydrofolate from formate and tetrahydrofolate YP_002263555.1 Similar to Escherichia coli ATP-dependent RNA helicase RhlE UniProt:P25888 (454 aa) fasta scores: E()=3.9e-67, 53.665% id in 382 aa YP_002263561.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide YP_002263562.1 HflD; UPF0274; in Escherichia coli this protein is peripherally associated with the membrane and appears to act with lambda CII protein; in Haemophilus influenzae a knockout of the HI0638 gene affected paracytosis YP_002263563.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs YP_002263564.1 Required for the expression of anaerobic nitric oxide (NO) reductase; acts as a transcriptional activator for the norVW operon YP_002263565.1 detoxifies nitric oxide using NADH YP_002263566.1 catalyzes the reduction of the rubredoxin moiety of nitric oxide reductase YP_002263572.1 Similar to Bacillus subtilis Stage V sporulation protein R SpoVR UniProt:P37875 (468 aa) fasta scores: E()=6.1e-33, 32.976% id in 467 aa YP_002263574.1 Similar to Bacillus subtilis Protein PrkA UniProt:P39134 (631 aa) fasta scores: E()=2.1e-47, 33.390% id in 587 aa YP_002263575.1 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate YP_002263579.1 involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation; binds to the N-terminal domain of the chaperone ClpA YP_002263580.1 ATPase and specificity subunit of the ClpA-ClpP ATP dependent serine protease; directs protease to specific substrates YP_002263581.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3 YP_002263582.1 Conjugates Arg from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate YP_002263583.1 leucyltransferase; phenylalanyltransferse; functions in the N-end rule pathway; transfers Leu, Phe, Met, from aminoacyl-tRNAs to N-terminal of proteins with Arg or Lys YP_002263584.1 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis YP_002263585.1 Catalyzes the formation of (d)CDP from ATP and (d)CMP YP_002263586.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins YP_002263587.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control YP_002263588.1 Similar to Escherichia coli Inner membrane protein YciS UniProt:P0ACV4 (102 aa) fasta scores: E()=1.6e-10, 42.169% id in 83 aa YP_002263590.1 type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase YP_002263591.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content YP_002263593.1 functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor YP_002263594.1 Similar to Escherichia coli Protein asmA precursor UniProt:P28249 (617 aa) fasta scores: E()=6.8e-07, 20.642% id in 717 aa. Possible alternative translational start site after codon 4. Expression may be regulated by Fur YP_002263595.1 catalyzes the formation of adenosylcob(III)yrinic acid a,c-diamide from cob(I)yrinic acid a,c-diamide YP_002263596.1 Similar to Vibrio vulnificus Hypothetical protein vv2095. UniProt:Q7MJR5 (509 aa) fasta scores: E()=1.7e-84, 55.000% id in 440 aa. No significant database matches to the full length CDS. Expression may be regulated by Fur YP_002263600.1 Similar to Escherichia coli Maf-like protein YceF UniProt:P0A729 (194 aa) fasta scores: E()=2.1e-41, 59.677% id in 186 aa YP_002263602.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not YP_002263603.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY YP_002263604.1 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs YP_002263606.1 catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis YP_002263607.1 FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP YP_002263608.1 catalyzes the formation of 4-aminobenzoate and pyruvate from 4-amino-4-deoxychorismate YP_002263609.1 Possible alternative translational start site after codon 42 YP_002263610.1 catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP) YP_002263611.1 Similar to Escherichia coli DNA polymerase III delta' subunit UniProt:P28631 (334 aa) fasta scores: E()=5.8e-21, 29.467% id in 319 aa YP_002263617.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel YP_002263621.1 Expression may be regulated by Fur YP_002263630.1 FadI; fatty acid oxidation complex component beta; functions in a heterotetramer with FadJ; similar to FadA2B2 complex; functions in beta-oxidation of fatty acids during anaerobic growth YP_002263631.1 Similar to Escherichia coli Long-chain fatty acid transport protein precursor FadL UniProt:P10384 (448 aa) fasta scores: E()=4.5e-22, 34.273% id in 461 aa YP_002263632.1 Similar to Escherichia coli Long-chain fatty acid transport protein precursor FadL UniProt:P10384 (448 aa) fasta scores: E()=6.3e-15, 32.096% id in 458 aa YP_002263633.1 Similar to Escherichia coli Inner membrane protein yjdF UniProt:P39270 (209 aa) fasta scores: E()=8.4e-15, 29.381% id in 194 aa YP_002263635.1 Similar to Escherichia coli cytochrome C biogenesis protein ccmH precursor UniProt:P0ABM9 (350 aa) fasta scores: E()=1.2e-21, 34.419% id in 215 aa YP_002263636.1 Similar to N-terminal part of Escherichia coli cytochrome C biogenesis protein CcmH precursor UniProt:P0ABM9 (350 aa) fasta scores: E()=4.6e-19, 49.612% id in 129 aa YP_002263639.1 CycJ; periplasmic heme chaperone that binds heme transiently via a histidine residue and delivers it to newly synthesized and c-type cytochromes; requires the ATP hydrolysis activity of the CcmA protein in order to transfer the heme to the apocytochrome; part of the cytochrome c maturation system; periplasmic protein anchored to the inner membrane YP_002263641.1 Expression may be regulated by Fur YP_002263643.1 ATP-binding protein; required for proper cytochrome c maturation YP_002263647.1 Similar to Bacillus subtilis Sporulation initiation inhibitor protein soj UniProt:P37522 (253 aa) fasta scores: E()=3.6e-25, 36.179% id in 246 aa YP_002263648.1 regulates chemotaxis by demethylation of methyl-accepting chemotaxis proteins YP_002263652.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor directs late flagellar biosynthesis genes YP_002263654.1 positive regulator of class III flagellar genes YP_002263655.1 membrane protein involved in the flagellar export apparatus YP_002263657.1 membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export YP_002263658.1 FliR, with proteins FliP and FliQ, forms the core of the central channel in the flagella export apparatus YP_002263659.1 with proteins FliP and FliR forms the core of the central channel in the flagella export apparatus YP_002263660.1 FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus YP_002263662.1 One of three proteins involved in switching the direction of the flagellar rotation YP_002263663.1 with FliG and FliN makes up the switch complex which is involved in switching the direction of the flagella rotation YP_002263664.1 interacts with the cytoplasmic MS ring of the basal body and may act to stabilize the MotAB complexes which surround the MS ring YP_002263665.1 Similar to C-terminal part of Vibrio parahaemolyticus Polar flagellar hook-length control protein FliK UniProt:Q9Z6G3 (643 aa) fasta scores: E()=2.7e-22, 51.381% id in 181 aa YP_002263666.1 rod/hook and filament chaperone YP_002263667.1 involved in type III protein export during flagellum assembly YP_002263668.1 binds to and inhibits the function of flagella specific ATPase FliI YP_002263669.1 One of three proteins involved in switching the direction of the flagellar rotation YP_002263670.1 forms a junction between the M-ring and FlgB during flagella biosynthesis YP_002263674.1 flagellin specific chaperone YP_002263676.1 involved in flagellin assembly YP_002263677.1 structural flagella protein; Vibrio contains multiple flagellin genes usually localized into two region on the chromosome, flaAC and flaCEDB in V. cholerae, flaFBA and flaCDE in V. parahemolyticus; FlaA is sigma 54 dependent and essential for motility in V.cholerae but not in V. parahaemolyticus YP_002263678.1 structural flagella protein; Vibrio contains multiple flagellin genes usually localized into two region on the chromosome, flaAC and flaCEDB in V. cholerae, flaFBA and flaCDE in V. parahemolyticus; FlaA is sigma 54 dependent and essential for motility in V.cholerae but not in V. parahaemolyticus YP_002263679.1 structural flagella protein; Vibrio contains multiple flagellin genes usually localized into two region on the chromosome, flaAC and flaCEDB in V. cholerae, flaFBA and flaCDE in V. parahemolyticus; FlaA is sigma 54 dependent and essential for motility in V.cholerae but not in V. parahaemolyticus YP_002263682.1 structural flagella protein; Vibrio contains multiple flagellin genes usually localized into two region on the chromosome, flaAC and flaCEDB in V. cholerae, flaFBA and flaCDE in V. parahemolyticus; FlaA is sigma 54 dependent and essential for motility in V.cholerae but not in V. parahaemolyticus YP_002263684.1 structural flagella protein; Vibrio contains multiple flagellin genes usually localized into two region on the chromosome, flaAC and flaCEDB in V. cholerae, flaFBA and flaCDE in V. parahemolyticus; FlaA is sigma 54 dependent and essential for motility in V.cholerae but not in V. parahaemolyticus YP_002263685.1 with FlgK acts as a hook filament junction protein to join the flagellar filament to the hook; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of this and other flagellar genes. YP_002263686.1 with FlgL acts as a hook filament junction protein to join the flagellar filament to the hook YP_002263687.1 Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space YP_002263688.1 part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum YP_002263689.1 part of the flagellar basal body which consists of four rings L,P, S and M mounted on a central rod YP_002263690.1 makes up the distal portion of the flagellar basal body rod YP_002263691.1 FlgF, with FlgB and C, makes up the proximal portion of the flagellar basal body rod YP_002263692.1 the hook connects flagellar basal body to the flagellar filament YP_002263693.1 acts as a scaffold for the assembly of hook proteins onto the flagellar basal body rod; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of some flagellar genes; in V. parahaemolyticus one set used for lateral flagella production and the other is used for the polar flagella production YP_002263694.1 with FlgF and B makes up the proximal portion of the flagellar basal body rod YP_002263695.1 with FlgF and C makes up the proximal portion of the flagellar basal body rod; Vibrio parahaemolyticus protein is associated with the polar flagella YP_002263698.1 required for the assembly of the flagellar basal body P-ring YP_002263707.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation YP_002263709.1 this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB YP_002263710.1 interacts with cell division protein FitsZ and may be required to anchor septal ring structure YP_002263711.1 role in sulfur assimilation YP_002263714.1 Phosphotransferase system, enzyme I; transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein; part of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active-transport system YP_002263715.1 functions in phosphoenolpyruvate-(PEP)-dependent phosphotransferase (PTS) system; functions in the transport and phosphorylation of glucose YP_002263718.1 Similar to Escherichia coli Inner membrane protein YfeZ UniProt:P76538 (149 aa) fasta scores: E()=5.3e-09, 33.333% id in 141 aa YP_002263727.1 Expression may be regulated by Fur YP_002263728.1 Expression may be stress-induced YP_002263730.1 dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica. YP_002263733.1 Similar to Escherichia coli Lipoprotein 34 precursor NlpB UniProt:P0A903 (344 aa) fasta scores: E()=1.6e-33, 33.832% id in 334 aa YP_002263734.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis YP_002263736.1 bacterioferritin comigratory protein; thiol peroxidase; thioredoxin-dependent; hydroperoxide peroxidase; in Escherichia coli this enzyme preferentially reduces linoleic acid hydroperoxide; contains an active site cysteine YP_002263744.1 Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate YP_002263745.1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis YP_002263748.1 catalyzes the isomerization of sedoheptulose 7-phosphate to D-glycero-D-manno-heptose 7-phosphate YP_002263750.1 functions in fatty acid oxidation; converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA YP_002263753.1 3'-5' exonuclease of DNA polymerase III YP_002263754.1 An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids YP_002263765.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein YP_002263766.1 catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase YP_002263767.1 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids YP_002263768.1 catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM YP_002263769.1 catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis YP_002263770.1 in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP YP_002263771.1 adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis YP_002263772.1 Similar to Yersinia pestis Chaperone protein skp precursor UniProt:P58607 (165 aa) fasta scores: E()=2e-16, 39.053% id in 169 aa YP_002263773.1 part of a complex with YfgL, YfiO, and NlpB involved in outer membrane protein biosynthesis; involved in the assembly of outer membrane proteins YP_002263775.1 catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate YP_002263778.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs YP_002263779.1 Catalyzes the phosphorylation of UMP to UDP YP_002263780.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu YP_002263781.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit YP_002263782.1 catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn YP_002263783.1 catalyzes the uridylylation or deuridylylation of the PII nitrogen regulatory protein YP_002263786.1 forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF YP_002263787.1 part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane YP_002263788.1 member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex YP_002263789.1 Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr) YP_002263790.1 Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step YP_002263791.1 Similar to N-terminal part of Bacillus subtilis Acetoin utilization protein AcuB UniProt:P39066 (214 aa) fasta scores: E()=1.1e-08, 30.986% id in 142 aa YP_002263793.1 Catalyzes the aldol condensation of glyoxylate with acetyl-CoA to form malate as part of the second step of the glyoxylate bypass and an alternative to the tricarboxylic acid cycle YP_002263794.1 Similar to Escherichia coli Hydrogen peroxide-inducible genes activator OxyR UniProt:P0ACQ4 (EMBL:J04553 (305 aa) fasta scores: E()=8.4e-29, 35.959% id in 292 aa YP_002263799.1 Similar to Pseudomonas putida HTH-type transcriptional activator NahR UniProt:P10183 (300 aa) fasta scores: E()=2.9e-13, 27.213% id in 305 aa YP_002263804.1 regulates several genes involved in high affinity phosphate uptake; under conditions of high phosphate concentrations downregulates the PHO regulon YP_002263805.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation YP_002263809.1 membrane-associated histidine protein kinase that phosphorylates phoB in response to environmental signals as part of the two-component phosphate regulatory system phoR/phoB YP_002263811.1 Required for efficient pilin antigenic variation YP_002263814.1 Similar to Acinetobacter sp. Cis,cis-muconate transport protein MucK UniProt:P94131 (413 aa) fasta scores: E()=2.7e-07, 23.636% id in 385 aa YP_002263816.1 Similar to Bacillus subtilis Ribose operon repressor RbsR UniProt:P36944 (326 aa) fasta scores: E()=4.1e-23, 33.333% id in 333 aa YP_002263820.1 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion YP_002263821.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria YP_002263824.1 catalyzes the phosphorylation of NAD to NADP YP_002263829.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation YP_002263840.1 antiporter protein responsible for lysine import and cadaverine export; member of the lysine-dependent acid resistance system 4 (AR4); inner membrane protein YP_002263842.1 regulates the cadBA operon YP_002263846.1 Similar to Yersinia enterocolitica Plasmid pYVe8081 YomA UniProt:Q93KR5 (291 aa) fasta scores: E()=2.3e-35, 44.170% id in 283 aa YP_002263847.1 catalyzes the formation of O-succinyl-L-homoserine from succinyl-CoA and L-homoserine in methionine biosynthesis YP_002263848.1 functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to DcuA; DcuA and DcuB function as independent and mutually redundant C4-dicarboxylate (aspartate, malate, fumarate and succinate) transporters YP_002263849.1 Similar to Escherichia coli Inner membrane transport protein yeiJ UniProt:P33021 (416 aa) fasta scores: E()=2.1e-48, 43.750% id in 416 aa YP_002263851.1 Similar to Serratia marcescens Iron(III)-transport system permease protein SfuB UniProt:P21409 (527 aa) fasta scores: E()=4.8e-05, 23.715% id in 506 aa YP_002263853.1 Similar to Escherichia coli Inner membrane protein YnjF UniProt:P76226 (206 aa) fasta scores: E()=1.5e-40, 58.049% id in 205 aa YP_002263856.1 catalyzes the methyl esterification of L-isoaspartyl residues that are formed in damaged proteins YP_002263857.1 catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate YP_002263858.1 catalyzes the modification of U13 in tRNA(Glu) YP_002263859.1 catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate YP_002263860.1 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers YP_002263863.1 CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer YP_002263865.1 structural flagella protein; Vibrio contains multiple flagellin genes usually localized into two region on the chromosome, flaAC and flaCEDB in V. cholerae, flaFBA and flaCDE in V. parahemolyticus; FlaA is sigma 54 dependent and essential for motility in V.cholerae but not in V. parahaemolyticus YP_002263867.1 in Escherichia coli this enzyme catalyzes the SAM-dependent methylation of U1939 in the 23S ribomal RNA; binds an iron-sulfur cluster [4Fe-4S] YP_002263868.1 part of the two-component regulatory system with UvrY; involved in the regulation of carbon metabolism via the csrA/csrB regulatory system YP_002263869.1 Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids YP_002263870.1 involved in the de novo synthesis of pyridoxine (Vitamin B6) YP_002263871.1 involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA YP_002263872.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome YP_002263873.1 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity YP_002263875.1 binds to the ribosome on the universally-conserved alpha-sarcin loop YP_002263876.1 Similar to Escherichia coli Sigma-E factor regulatory protein RseC UniProt:P46187 (159 aa) fasta scores: E()=2.8e-09, 32.877% id in 146 aa YP_002263877.1 periplasmic protein; interacts with the C-terminal domain of RseA and stimulates RseA binding to sigmaE via the cytoplasmic RseA N-terminal domain which then sequesters sigmaE in the membrane thereby preventing sigmaE associated with core RNAP YP_002263879.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor is involved in heat shock and oxidative stress response YP_002263880.1 catalyzes the formation of oxaloacetate from L-aspartate YP_002263881.1 CDS contanins a rare Valine start codon (GTT) YP_002263885.1 catalyzes the formation of 2-octaprenyl-6-methoxy-1,4-benzoquinone from 2-octaprenyl-6-methoxyphenol YP_002263886.1 Oxygenase that introduces the hydroxyl group at carbon four of 2-octaprenyl-6-methoxyphenol resulting in the formation of 2-octaprenyl-6-methoxy-1,4-benzoquinone YP_002263887.1 the crystal structure of Haemophilus influenzae HI0817 showed that this protein forms dimers; function unknown YP_002263890.1 Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway YP_002263892.1 catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate YP_002263896.1 Similar to Escherichia coli transporter YaaJ UniProt:P30143 (476 aa) fasta scores: E()=1.4e-85, 51.392% id in 467 aa YP_002263899.1 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine YP_002263900.1 Assists in DNA repair by cleaving phosphodiester bonds at apurinic or apyrimidinic sties to produce new 5' ends that are base-free deoxyribose 5-phosphate residues YP_002263901.1 stress-induced glycyl radical protein that can replace an oxidatively damaged pyruvate formate-lyase subunit YP_002263902.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine YP_002263903.1 catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate YP_002263904.1 multifunctional homotetrameric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways YP_002263905.1 regulator of RNase E; increases half-life and abundance of RNAs; interacts with RNase E possibly inhibiting catalytic activity YP_002263908.1 sensor-regulator protein which regulates the expression of many genes in response to respiratory growth conditions including anaerobic repression of the arc modulon; hybrid sensory histidine kinase in two-component regulatory system with ArcA YP_002263909.1 Similar to Synechocystis sp. Ferredoxin-dependent glutamate synthase 1 GltB UniProt:P55037 (1550 aa) fasta scores: E()=0, 54.714% id in 1506 aa YP_002263910.1 glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate YP_002263912.1 enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine YP_002263913.1 catalyzes the formation of adenosylcobinamide-phosphate from adenosylcobyric acid YP_002263914.1 Similar to Escherichia coli Inner membrane protein YadS UniProt:P0AFP0 (207 aa) fasta scores: E()=3e-47, 65.686% id in 204 aa YP_002263916.1 Similar to Escherichia coli multidrug resistance protein MdtB UniProt:P76398 (1040 aa) blastp scores: E()=3e-49 YP_002263917.1 Similar to Pseudomonas aeruginosa Multidrug resistance protein MexA (PDB 1T5E), evalue=4e-09 identity=(69, 326) YP_002263918.1 essential respiratory protein A; may be involved in the transfer of iron-sulfur clusters; essential for growth using oxygen or alternate electron acceptors YP_002263919.1 Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway YP_002263920.1 Expression may be stress-induced YP_002263922.1 Similar to Endosymbiont of Riftia pachyptila Sensor protein RssA UniProt:O33541 (773 aa) fasta scores: E()=4e-31, 31.076% id in 502 aa YP_002263923.1 Similar to Bacillus subtilis Oligopeptide transport system permease protein OppB UniProt:P24138 (311 aa) blastp scores: E()=2e-38 YP_002263924.1 Similar to Bacillus subtilis Oligopeptide transport system permease protein AppC UniProt:P42063 (303 aa) blastp scores: E()=1e-31 YP_002263925.1 Similar to Bacillus subtilis Dipeptide transport ATP-binding protein DppD UniProt:P26905 (335 aa) fasta scores: E()=2e-41, 42.722% id in 316 aa YP_002263926.1 Similar to Bacillus subtilis Oligopeptide transport ATP-binding protein appF UniProt:P42065 (329 aa) fasta scores: E()=1.1e-34, 38.138% id in 333 aa YP_002263933.1 Similar to Pasteurella haemolytica transmembrane permease FbpB UniProt:Q9ZHY1 (525 aa) fasta scores: E()=7.9e-94, 53.565% id in 519 aa YP_002263934.1 Expression may be regulated by Fur YP_002263935.1 Similar to Pseudomonas stutzeri ammonium transporter Amtb2 UniProt:Q8RPB0 (417 aa) fasta scores: E()=1.9e-74, 64.649% id in 413 aa YP_002263939.1 Similar to Escherichia coli High-affinity gluconate transporter GntP UniProt:P0AC94 (447 aa) fasta scores: E()=5.5e-06, 24.146% id in 439 aa YP_002263941.1 catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate YP_002263947.1 similar in sequence to the ATP-dependent RNA helicase HrpA YP_002263950.1 Similar to Escherichia coli Poly(A) polymerase PcnB UniProt:P0ABF1 (472 aa) fasta scores: E()=6.1e-99, 57.798% id in 436 aa. The CDS appears to be truncated at the N-terminus YP_002263952.1 catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate YP_002263953.1 catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine YP_002263956.1 Similar to Escherichia coli Inner membrane transport permease YadH UniProt:P0AFN6 (256 aa) fasta scores: E()=2.4e-55, 69.141% id in 256 aa YP_002263957.1 Similar to Thermotoga maritima msb8 ABC transporter ATP-binding protein (TM0544) (PDB 1VPL), evalue=4e-36 identity=(82, 233) YP_002263963.1 E3 component of pyruvate and 2-oxoglutarate dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide YP_002263964.1 E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC YP_002263965.1 activates lctPRD operon; autoregulates itself through repression of pdhR-aceEF-lpdA operon; regulates pyruvate dehydrogenase complex YP_002263967.1 catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide YP_002263975.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins YP_002263977.1 zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis YP_002263978.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function YP_002263979.1 ATP-binding involved in recruitment of FtsK to Z ring; essential cell division protein; colocalizes with FtsZ through direct interaction to the septal ring structure; structurally similar to eukaryotic actin; binds directly to the cell membrane YP_002263981.1 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis YP_002263982.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis YP_002263984.1 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation YP_002263985.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan YP_002263991.1 Similar to Bacteroides thetaiotaomicron VPI-5482 S-adenosylmethionine-dependent methytransferase (PDB 1WYZ), evalue=6e-15 identity=(52, 204) YP_002263997.1 transcriptional activator; required for activation of bacteriophage P1 late promoter; induced by starvation YP_002263998.1 Similar to Bradyrhizobium japonicum Cytochrome b/c1 FbcH UniProt:P51131 (687 aa) blastp scores: E()=2e-11 YP_002264001.1 forms a direct contact with the tRNA during translation YP_002264002.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit YP_002264007.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling YP_002264008.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling YP_002264009.1 Displays esterase activity toward palmitoyl-CoA and pNP-butyrate YP_002264010.1 Similar to Escherichia coli Protein icc UniProt:P0AEW4 (275 aa) fasta scores: E()=1.1e-56, 52.490% id in 261 aa YP_002264013.1 trimeric outer membrane protein involved in efflux of hydrophobic/amphipathic molecules; functions with a number of efflux systems in the inner membrane to transport molecules out of the cell YP_002264014.1 catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate to form D,D-heptose-1,7-bisphosphate and catalyzes transfer of ADP to D-glycero-D-manno-heptose 1-phosphate forming ADP-D,D-heptose YP_002264015.1 catalyzes the ATP-dependent addition of AMP to a subunit of glutamine synthetase; also catalyzes the reverse reaction - deadenylation; adenylation/deadenylation of glutamine synthetase subunits is important for the regulation of this enzyme YP_002264027.1 catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template; phosphohydrolase activities include hydrolysis of pyrophosphate, 5'-nucleoside tri- and diphosphates, NADP, and 2'-AMP with the production of Pi, metal-dependent phosphodiesterase activity for 2',3'-cAMP, 2',3'-cGMP, and 2',3'-cCMP, and hydrolysis 2',3'-cyclic substrates with the formation of 2'-nucleotides and 3'-nucleotides; these phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases YP_002264028.1 BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell YP_002264029.1 Similar to Haemophilus influenzae 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase FolK UniProt:P43777 (160 aa) fasta scores: E()=8.2e-09, 35.948% id in 153 aa YP_002264031.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX YP_002264032.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity YP_002264034.1 synthesizes RNA primers at the replication forks YP_002264035.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this is the primary sigma factor of bacteria YP_002264036.1 Similar to Bacillus subtilis Long-chain-fatty-acid--CoA ligase LcfA UniProt:P94547 (560 aa) fasta scores: E()=1.9e-47, 34.594% id in 529 aa YP_002264038.1 catalyzes the formation of phosphoenolpyruvate from pyruvate YP_002264042.1 with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit YP_002264047.1 catalyzes the formation of arginine from (N-L-arginino)succinate and the formation of N-acetylglutamate from glutamate and acetyl-CoA YP_002264049.1 Catalyzes the oxidation of dihydrolipoamide to lipoamide YP_002264051.1 Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG, gor, ahpC, ahpF, oxyS, dps, fur and grxA YP_002264053.1 Similar to Myxococcus xanthus dk 1622 PilM UniProt:Q306N6 (366 aa) fasta scores: E()=1.3e-10, 24.085% id in 328 aa YP_002264054.1 Similar to Pseudomonas aeruginosa Type 4 fimbrial biogenesis protein PilN UniProt:Q51352 (198 aa) fasta scores: E()=1e-09, 26.452% id in 155 aa YP_002264055.1 Similar to Pseudomonas fluorescens Type IV pilus biogenesis protein PilO UniProt:Q4KJJ2 (207 aa) fasta scores: E()=6.3e-17, 35.106% id in 188 aa YP_002264056.1 Similar to Pseudomonas syringae Pilus expression protein PilP UniProt:Q52542 (175 aa) fasta scores: E()=7.2e-08, 28.481% id in 158 aa YP_002264058.1 type I enzyme similar to type II but differentially regulated; major shikimate kinase in fully repressed cells; catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis YP_002264059.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis YP_002264060.1 Similar to Escherichia coli Protein DamX UniProt:P11557 (428 aa) fasta scores: E()=0.004, 23.109% id in 238 aa YP_002264062.1 catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate YP_002264063.1 catalyzes the dephosphorylation of 2-phosphoglycolate to form glycolate and phosphate YP_002264064.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_002264065.1 aminodeoxychorismate synthase subunit PabA; with PabB catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and glutamine in para-aminobenzoate synthesis; PabA provides the glutamine amidotransferase activity YP_002264069.1 DapATase; bifunctional enzyme that functions in arginine and lysine biosynthetic pathways; catalyzes the formation of N-acetyl-L-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine or N-succinyl-2-L-amino-6-oxoheptanedioate from 2-oxoglutarate and N-succinyl-L-2,6-diaminoheptanedioate YP_002264071.1 a high throughput screen identified this enzyme as an aldehyde dehydrogenase with broad substrate specificity; converts succinylglutamate semialdehyde and NAD to succinylglutamate and NADH YP_002264073.1 complexes with cyclic AMP and binds to specific DNA sites near the promoter to regulate the transcription of several catabolite-sensitive operons YP_002264075.1 heat shock protein involved in degradation of misfolded proteins YP_002264076.1 heat shock protein involved in degradation of misfolded proteins YP_002264077.1 Similar to Escherichia coli Divisome protein FtsN (PDB 1UTA), evalue=2e-06 identity=(22, 67) YP_002264078.1 negatively controls the transcription initiation of genes such as deoCABD, udp, and cdd encoding catabolizing enzymes and nupC, nupG, and tsx encoding transporting and pore-forming proteins YP_002264079.1 binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity YP_002264080.1 RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome YP_002264082.1 when combined with S-adenosylmethionine represses the expression of the methionine regulon and of proteins involved in S-adenosylmethionine synthesis YP_002264083.1 catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine YP_002264084.1 multifunctional homodimeric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways YP_002264085.1 activator for leuABCD operon; member of LysR family of transcriptional activators YP_002264090.1 catalyzes the formation of oxaloacetate from phosphoenolpyruvate YP_002264091.1 catalyzes the formation of L-ornithine from N(2)-acetyl-L-ornithine in arginine biosynthesis YP_002264092.1 catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate YP_002264093.1 catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate YP_002264094.1 catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming YP_002264098.1 MTHFR; catalyzes NADH-linked reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate using FAD as a cofactor YP_002264099.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk YP_002264100.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit YP_002264101.1 binds single-stranded DNA at the primosome assembly site YP_002264102.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21 YP_002264103.1 Specifically methylates the ribose of guanosine 2251 in 23S rRNA YP_002264105.1 negatively regulates the transcription of genes upregulated by nitrosative stress YP_002264106.1 flavohemoprotein; catalyzes the formation of nitrate from nitric oxide; can also catalyze the reduction of dihydropteridine YP_002264108.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis YP_002264112.1 involved in modulation of proteins HflK and HflC; part of the hflA locus (high frequency of lysogenization) which governs the lysis-lysogeny decision of bacteriophage lambda by controlling stability of the phage cII protein YP_002264113.1 Stimulates the elongation of poly(A) tails YP_002264114.1 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity YP_002264115.1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex YP_002264119.1 3'-5' exoribonuclease specific for small oligoribonuclotides YP_002264120.1 EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity YP_002264121.1 catalyzes the decarboxylation of phosphatidyl-L-serine to phosphatidylethanoleamine YP_002264122.1 Possible alternative translational start site after codon 23 YP_002264123.1 lysine--tRNA ligase beta chain; poxA; class II aminoacyl tRNA synthetase; catalyzes a two-step reaction; first charging a lysine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_002264124.1 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB YP_002264125.1 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB YP_002264126.1 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB YP_002264127.1 in conjunction with FrdC acts to anchor the catalytic components of the fumarate reductase to the cytoplasmic membrane YP_002264128.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA YP_002264129.1 Similar to Clostridium subterminale L-lysine 2,3-aminomutase KamA UniProt:Q9XBQ8 (416 aa) fasta scores: E()=3.9e-30, 33.746% id in 323 aa YP_002264130.1 catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis YP_002264131.1 member of cation diffusion facilitator family; CDF; membrane-bound; induced by both zinc and iron, but does not induce resistance to zinc; can transport zinc(II) in a proton-dependent manner; instead this protein induces iron resistance; forms dimers YP_002264132.1 Similar to Escherichia coli Periplasmic protein CpxP UniProt:P0AE85 (166 aa) fasta scores: E()=5.9e-05, 36.842% id in 114 aa YP_002264134.1 part of two-component CpxA/CpxR system; senses envelope stress; upregulates a number of periplasmic folding and trafficking factors YP_002264135.1 Similar to Escherichia coli Hypothetical tRNA/rRNA methyltransferase YibK UniProt:P0AGJ7 (157 aa) fasta scores: E()=2.7e-36, 60.377% id in 159 aa YP_002264136.1 catalyzes the O-acetylation of serine YP_002264137.1 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate YP_002264138.1 molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be to SecA YP_002264141.1 F exclusion of bacteriophage T7; overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7; interacts with the F plasmid-encoded PifA protein; inner membrane protein YP_002264142.1 catalyzes the formation of fumarate from aspartate YP_002264145.1 two electrons are transferred from cytoplasmic NADPH to thioredoxin and then to the inner membrane protein DsbD which keeps the disulfide isomerase DsbC in a reduced state in the oxidizing periplasm; DsbC in turns rearranges incorrectly made disulfide bonds in the periplasm YP_002264146.1 catalyzes the reversible formation of fructose 6-phosphate from glucosamine 6-phosphate YP_002264149.1 Acts as a repressor of the mtlAD operon YP_002264152.1 catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate YP_002264153.1 Expression may be regulated by Fur YP_002264156.1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source YP_002264157.1 Similar to Escherichia coli Glucitol operon repressor SrlR UniProt:P15082 (257 aa) fasta scores: E()=4.4e-28, 44.130% id in 247 aa YP_002264161.1 Similar to Vibrio fischeri Hypothetical protein UniProt:Q5E275 (88 aa) fasta scores: E()=2.9e-27, 86.364% id in 88 aa. Possible alternative translational start site after codon 25 YP_002264164.1 transporter of 3-phenylpropionate across the inner membrane; member of the major facilitator superfamily of transporters YP_002264166.1 3'-5' exonuclease of DNA polymerase III YP_002264167.1 Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA YP_002264168.1 catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis YP_002264169.1 composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism YP_002264171.1 methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype YP_002264173.1 Stimulates excision of phage lambda; affects Mu development; acts as an activator of rRNA and iRNA transcription YP_002264175.1 mediates expression of the zinc export protein ZntA in response to high levels of zinc; member of MerR family of transcriptional regulators YP_002264176.1 involved in de novo purine biosynthesis YP_002264177.1 catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis YP_002264181.1 Expression may be regulated by Fur YP_002264185.1 catalyzes the formation of coproporphyrinogen from uroporphyrinogen III YP_002264187.1 binds specifically to the major sigma factor sigma 70; active in stationary phase YP_002264188.1 Similar to Escherichia coli Curli production assembly/transport component CsgF precursor UniProt:P0AE98 (138 aa) fasta scores: E()=1.4e-13, 39.516% id in 124 aa YP_002264189.1 Similar to Salmonella typhimurium Curli production assembly/transport component CsgE precursor UniProt:P0A200 (131 aa) fasta scores: E()=0.00033, 34.862% id in 109 aa YP_002264190.1 Similar to Escherichia coli CsgAB operon transcriptional regulatory protein UniProt:P52106 (216 aa) fasta scores: E()=8.1e-12, 38.217% id in 157 aa YP_002264195.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter YP_002264196.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme YP_002264197.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors YP_002264198.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit YP_002264199.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA YP_002264200.1 binds directly to 23S ribosomal RNA YP_002264201.1 Modulates Rho-dependent transcription termination YP_002264202.1 forms a complex with SecY and SecG; SecYEG forms a protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force YP_002264205.1 catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis YP_002264206.1 catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon YP_002264207.1 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis YP_002264209.1 catalyzes de novo synthesis of phosphatidylserine from CDP-diacylglycerol and L-serine which leads eventually to the production of phosphatidylethanolamine; bounds to the ribosome YP_002264214.1 converts L-glutamate to D-glutamate, a component of peptidoglycan YP_002264216.1 Similar to Salmonella typhimurium Vitamin B12 transporter BtuB precursor UniProt:P37409 (614 aa) fasta scores: E()=3.2e-56, 34.615% id in 624 aa YP_002264217.1 catalyzes the formation of 5-methyl-uridine at position 54 in all tRNAs YP_002264218.1 Similar to Escherichia coli Inner membrane protein YijD UniProt:P0AF40 (119 aa) fasta scores: E()=4.7e-11, 35.897% id in 117 aa YP_002264219.1 negatively controls the expression of fabA and fabB, genes involved in the unsaturated fatty acid biosynthesis YP_002264220.1 catalyzes the conversion of NADPH to NADH YP_002264222.1 Expression may be regulated by Fur YP_002264223.1 Represses a number of genes involved in the response to DNA damage YP_002264224.1 PlsB; catalyzes the formation of 1-acyl-sn-glycerol 3-phosphate by transfering the acyl moiety from acyl-CoA YP_002264225.1 catalyzes the conversion of 4-Hydroxybenzoate into 3-octaprenyl-4-hydroxybenzoate, as part of the ubiquinone biosynthesis pathway YP_002264226.1 Similar to Escherichia coli Chorismate--pyruvate lyase UbiC UniProt:P26602 (164 aa) fasta scores: E()=4.3e-12, 33.803% id in 142 aa YP_002264229.1 belongs to rhodanese family; thiosulfate thiotransferase; in Escherichia coli this enzyme catalyzes the formation of thiocyanate from thiosulfate and cyanide with low efficiency; contains an active site cysteine YP_002264230.1 binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters YP_002264239.1 catalyzes branch migration in Holliday junction intermediates YP_002264240.1 cytoplasmic protein that may be involved in the utilization of double-stranded DNA as a carbon source YP_002264242.1 ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose YP_002264245.1 CDS contanins a rare Leucine start codon (CTG) YP_002264256.1 becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers YP_002264257.1 PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP YP_002264265.1 hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine YP_002264266.1 RNase BN; required for 3' maturation of certain phage T4-encoded tRNAs; forms a dimer; specific for immature tRNA substrates containing incorrect residues within the universal CCA sequence; 3' to 5' exoribonuclease YP_002264267.1 Similar to Escherichia coli GTP-binding protein TypA/BipA (Tyrosine phosphorylated protein A) UniProt:P32132 (607 aa) fasta scores: E()=1.6e-162, 74.503% id in 604 aa. Expression may be stress-induced YP_002264268.1 forms a homododecamer; forms glutamine from ammonia and glutamate with the conversion of ATP to ADP and phosphate; also functions in the assimilation of ammonia; highly regulated protein controlled by the addition/removal of adenylyl groups by adenylyltransferase from specific tyrosine residues; addition of adenylyl groups results in inactivation of the enzyme YP_002264272.1 transcriptional repressor of asnA which codes for aspartate-ammonia ligase YP_002264276.1 ppGpp-dependent, membrane associated, stress protein produced under conditions of nutrient deprivation, osmotic shock and oxidative stress YP_002264288.1 transaminase C; catalyzes transamination of alanine, valine, and 2-aminobutyrate with their respective 2-keto acids; also catalyzes terminal step in valine biosynthesis YP_002264289.1 glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_002264290.1 glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_002264291.1 periplasmic enzyme that degrades maltodextrins that enter via the outer membrane porin LamB; hydrolyzes alpha-(1,4) glycosidic linkages; contains internal disulfide bonds YP_002264293.1 TusA; transfers sulfur to TusBCD complex; involved in thiouridation of U34 position of some tRNAs YP_002264298.1 FadA; fatty acid oxidation complex component beta; functions in a heterotetramer with FadB; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids YP_002264299.1 includes enoyl-CoA hydratase, delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase, 3-hydroxyacyl-CoA dehydrogenase, and 3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities; forms a heterotetramer with FadA; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids YP_002264302.1 catalyzes the oxidation of protoporphyrinogen IX to form protoporphyrin IX YP_002264303.1 No significant database matches. Expression may be regulated by Fur YP_002264306.1 may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling YP_002264308.1 required for the synthesis of the hydromethylpyrimidine moiety of thiamine YP_002264310.1 Possible alternative translational start site after codon 5 YP_002264312.1 functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate YP_002264313.1 in Escherichia coli this enzyme functions in thiamine biosynthesis along with thiFSGI and iscS; with ThiFSG catalyzes the formation of thiazole phosphate from tyrosine, cysteine and 1-deoxy-D-xylulose-5-phosphate; forms a complex with ThiG; contains an iron-sulfur center YP_002264316.1 Similar to Escherichia coli HTH-type transcriptional regulator YidZ UniProt:P31463 (319 aa) fasta scores: E()=6.7e-30, 32.595% id in 316 aa YP_002264317.1 Similar to Escherichia coli Multidrug resistance protein MdtL UniProt:P31462 (391 aa) fasta scores: E()=9.7e-26, 29.919% id in 371 aa YP_002264320.1 Similar to Escherichia coli DNA recombination protein RmuC UniProt:P0AG71 (475 aa) fasta scores: E()=2.3e-78, 55.305% id in 443 aa. Lack of similarity at the N-terminus in comparison to other proteins YP_002264321.1 Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone YP_002264323.1 an Escherichia coli mutant results in accumulation of octaprenylphenol and no ubiquinone; functions in the formation of 2-octaprenyl-6-hydroxy-phenol from 2-octaprenylphenol in ubiquinone (coenzyme Q) biosynthesis; similar to eukaryotic proteins that exhibit kinase functions YP_002264324.1 TatA; similar to TatE that is found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes YP_002264325.1 mediates the export of protein precursors bearing twin-arginine signal peptides YP_002264329.1 catalyzes the formation of porphobilinogen from 5-aminolevulinate YP_002264340.1 Similar to Escherichia coli NeuNAc transferase WbwA UniProt:Q93NP9 (316 aa) fasta scores: E()=5.9e-14, 29.283% id in 321 aa YP_002264341.1 NAD(P) binding; catalyzes the formation of dTDP-4-dehydro-6-deoxy-D-glucose from dTDP-glucose YP_002264345.1 Similar to Escherichia coli glycosyltransferase WcaN UniProt:Q9X4C3 (287 aa) fasta scores: E()=1.5e-10, 32.489% id in 237 aa YP_002264347.1 Similar to Shigella boydii glycosyltransferase WbsW UniProt:Q6QQW8 (280 aa) fasta scores: E()=2.9e-07, 29.515% id in 227 aa YP_002264349.1 Similar to Escherichia coli lipopolysaccharide biosynthesis O-acetyl transferase WbbJ UniProt:P37750 (196 aa) fasta scores: E()=2e-08, 35.000% id in 140 aa YP_002264351.1 Similar to Aeromonas hydrophila lipopolysaccharide biosynthesis protein UniProt:Q8KXE8 (332 aa) fasta scores: E()=1.8e-14, 28.763% id in 299 aa YP_002264352.1 Similar to Pseudomonas aeruginosa O-antigen biosynthetic gene WbjF UniProt:P95426 (314 aa) fasta scores: E()=2.4e-35, 42.321% id in 293 aa YP_002264354.1 Similar to Vibrio cholerae o139 epimerase/dehydratase UniProt:Q56627 (646 aa) fasta scores: E()=6.8e-152, 70.671% id in 641 aa YP_002264359.1 Similar to Edwardsiella ictaluri glycosyltransferase WbeiB UniProt:Q937Y0 (261 aa) fasta scores: E()=1.8e-11, 32.099% id in 243 aa YP_002264367.1 catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate YP_002264372.1 forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis YP_002264373.1 part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane YP_002264374.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit YP_002264375.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit YP_002264376.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit YP_002264377.1 Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex YP_002264378.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel. YP_002264379.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0 YP_002264380.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0 YP_002264381.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation YP_002264382.1 Similar to Bacillus subtilis Stage 0 sporulation protein J UniProt:P26497 (282 aa) blastp scores: E()=3e-41 YP_002264384.1 glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA YP_002264385.1 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs YP_002264386.1 Similar to Vibrio harveyi RctB UniProt:Q6W6R5 (662 aa) fasta scores: E()=6e-178, 69.970% id in 656 aa YP_002264391.1 Similar to Escherichia coli ATP-dependent DNA helicase RecQ UniProt:P15043 (608 aa) fasta scores: E()=2.7e-51, 45.201% id in 323 aa YP_002264395.1 Similar to Enterobacter aerogenes AcrA protein precursor UniProt:Q9AEG2 (399 aa) fasta scores: E()=2.3e-33, 34.973% id in 366 aa YP_002264397.1 Similar to Pseudomonas aeruginosa Outer membrane porin F precursor OprF UniProt:P13794 (350 aa) fasta scores: E()=3.2e-14, 37.179% id in 156 aa YP_002264399.1 Similar to Staphylococcus hyicus Biofilm-associated protein Bap UniProt:Q4ZHU0 (3278 aa) fasta scores: E()=2.4e-25, 24.872% id in 2738 aa. Expression may be regulated by Fur YP_002264400.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate YP_002264412.1 Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides YP_002264414.1 amylomaltase; acts to release glucose from maltodextrins YP_002264422.1 Similar to Escherichia coli Inner membrane protein YcdZ UniProt:P75916 (163 aa) fasta scores: E()=9.8e-34,68.243% id in 148 aa YP_002264429.1 Similar to Pseudomonas aeruginosa Alkaline protease secretion protein AprF UniProt:Q03027 (481 aa) fasta scores: E()=1.8e-12, 20.588% id in 408 aa YP_002264430.1 Similar to Pseudomonas fluorescens Zinc-protease transporter AprD UniProt:O67993 (579 aa) fasta scores: E()=5.1e-09, 22.770% id in 527 aa YP_002264431.1 Similar to Serratia marcescens Secretion protein LipB UniProt:Q54456 (588 aa) fasta scores: E()=5.4e-21,24.291% id in 564 aa YP_002264432.1 Similar to Bacillus sp Lichenase precursor Bga1 UniProt:Q45648 (276 aa) fasta scores: E()=9.2e-22, 36.538% id in 260 aa YP_002264434.1 Similar to Yersinia ruckeri Putative ATP-binding metalloprotease secretion protein UniProt:Q8VLR8 (580 aa) fasta scores: E()=1.2e-60, 38.283% id in 559 aa YP_002264435.1 Similar to Rhizobium meliloti Membrane fusion protein Expd2 UniProt:O05198 (473 aa) fasta scores: E()=1.1e-33, 28.538% id in 424 aa YP_002264442.1 catalyzes the hydrolysis of 2-N-succinylarginine into 2-N-succinylornithine, ammonia and carbon dioxide in arginine degradation YP_002264443.1 Expression may be regulated by Fur YP_002264448.1 Expression may be stress-induced YP_002264457.1 binds D-fructose as an inducer; involved in regulation of operons for central pathways of carbon metabolism YP_002264458.1 phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIA is phosphorylated by phospho-HP which then transfers the phosphoryl group to the IIB componentr YP_002264466.1 Expression may be stress-induced YP_002264468.1 Similar to Pseudomonas sp Carboxypeptidase G2 precursor Cpg2 UniProt:P06621 (415 aa) fasta scores: E()=1.6e-11, 25.849% id in 383 aa YP_002264471.1 Expression may be regulated by Fur YP_002264474.1 Similar to Salmonella typhimurium Ferrioxamine B receptor precursor FoxA UniProt:Q56145 (702 aa) fasta scores: E()=8.7e-31, 26.752% id in 628 aa. Expression may be regulated by Fur YP_002264482.1 Similar to Pasteurella piscicida Putative iron-regulated protein (fragment) UniProt:Q6ZXD3 (106 aa) fasta scores: E()=1.7e-17, 54.054% id in 111 aa. Expression may be regulated by Fur YP_002264484.1 Possible alternative translational start site after codon 10 YP_002264487.1 Similar to Streptococcus sanguis Manganese ABC transporter substrate-binding lipoprotein precursor SsaB UniProt:P31304 (309 aa) fasta scores: E()=8.1e-14, 26.774% id in 310 aa YP_002264488.1 Similar to Bacillus subtilis Manganese transport system ATP-binding protein MntB UniProt:O34338 (250 aa) fasta scores: E()=5.7e-17, 33.047% id in 233 aa YP_002264491.1 Weakly similar Streptococcus pyogenes Putative recombinase-phage-associated UniProt:Q8K7P3 (191 aa) fasta scores: E()=3.9e-05, 32.174% id in 115 aa YP_002264496.1 GbpA; plays a role mediating bacterial attachment and colonization of zooplankton and/or intestinal epithelium; in Vibrio cholerae this protein probably binds directly N-acetylglucosamine residues in chitin, glycoproteins and lipids on intestinal epithelial cells YP_002264497.1 Similar to Escherichia coli Cytochrome b561 homolog 2 UniProt:P75925 (188 aa) fasta scores: E()=6.9e-05,26.966% id in 178 aa YP_002264501.1 Similar to Vibrio fischeri PilA UniProt:Q8KTJ5 (128 aa) fasta scores: E()=1e-05, 35.583% id in 163 aa. CDS contains additional internal amino acids, residues 63 to 100, in comparison to Vibrio fischeri orthologue YP_002264504.1 Similar to Escherichia coli Putative ATP-dependent RNA helicase RhlE UniProt:P25888 (454 aa) fasta scores: E()=2.9e-84, 58.590% id in 454 aa YP_002264505.1 Expression may be regulated by Fur YP_002264507.1 multidrug efflux protein involved in adaptation to low energy shock YP_002264508.1 exhibits an RNA-dependent ATPase activity, specifically stimulated by bacterial 23S rRNA YP_002264510.1 Similar to Bordetella bronchiseptica AlcD UniProt:O52832 (267 aa) fasta scores: E()=2.3e-12, 25.630% id in 238 aa. Expression may be regulated by Fur YP_002264511.1 Similar to Bacillus subtilis Multidrug resistance protein 1 Bmr UniProt:P33449 (389 aa) fasta scores: E()=0.00092, 20.588% id in 374 aa. Expression may be regulated by Fur YP_002264512.1 Expression may be regulated by Fur YP_002264514.1 part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter involved in the high-affinity transport of Fe(3+)-ferrichrome YP_002264522.1 Similar to Pseudomonas putida CyoC UniProt:Q6S4M5 (208 aa) fasta scores: E()=1.5e-48, 65.128% id in 195 aa YP_002264523.1 Expression may be regulated by Fur YP_002264530.1 Similar to Vibrio cholerae Toxin coregulated pilus biosynthesis protein I TcpI UniProt:P29486 (620 aa) fasta scores: E()=1.3e-31, 37.203% id in 379 aa YP_002264538.1 Similar to Escherichia coli HTH-type transcriptional regulator HdfR UniProt:P0A8R9 (279 aa) fasta scores: E()=2.5e-34, 41.429% id in 280 aa YP_002264539.1 EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity YP_002264550.1 Similar to Acinetobacter baumannii BfmS UniProt:Q2VSW5 (549 aa) fasta scores: E()=5.5e-21, 33.234% id in 334 aa YP_002264553.1 Similar to Escherichia coli Sensor kinase CusS UniProt:P77485 (480 aa) fasta scores: E()=1.2e-33, 29.787% id in 470 aa YP_002264564.1 Similar to Pseudomonas aeruginosa Gluconate permease GnuT UniProt:Q9ZIJ1 (450 aa) fasta scores: E()=1e-34, 29.306% id in 447 aa YP_002264565.1 catalyzes the reaction of formaldehyde with glutathione to form S-hydroxymethylglutathione YP_002264575.1 Expression may be regulated by Fur YP_002264581.1 involved in the import of serine and threonine coupled with the import of sodium YP_002264583.1 Similar to Sulfolobus acidocaldarius Glycogen debranching enzyme (Amylase) TreX UniProt:O05152 (713 aa) fasta scores: E()=3.7e-85, 38.576% id in 674 aa YP_002264587.1 Similar to Vibrio fischeri Hypothetical protein UniProt:Q5DZB9 (217 aa) fasta scores: E()=2.2e-72, 86.190% id in 210 aa. CDS may be truncated by the insertion of the downstream IS element and subsequent recombination events YP_002264588.1 catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate YP_002264589.1 catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose YP_002264598.1 Expression may be stress-induced and may be regulated by Fur YP_002264602.1 Similar to Vibrio sp. 14a09 Putative 3-hydroxy-3-methylglutaryl coenzyme A reductase UniProt:Q2UXT1 (218 aa) fasta scores: E()=1.2e-72, 91.743% id in 218 aa YP_002264603.1 catalyzes the formation of agmatine from arginine in putrescine and spermidine biosynthesis YP_002264608.1 CDS contains a rare Leucine start codon (TTA), or may be truncated by the insertion of the upstream IS element YP_002264614.1 Similar to Mycobacterium tuberculosis Putative virulence-regulating 38 kDa protein VirS UniProt:Q06861 (340 aa) fasta scores: E()=6e-17, 23.724% id in 333 aa YP_002264623.1 Expression may be regulated by Fur YP_002264652.1 Similar to Streptococcus pneumoniae Capsular polysaccharide synthesis protein cps14D UniProt:P72512 (227 aa) fasta scores: E()=7.4e-05, 26.738% id in 187 aa YP_002264653.1 Similar to Vibrio fischeri Transporter UniProt:Q5DYQ4 (703 aa) fasta scores: E()=0, 90.612% id in 703 aa YP_002264656.1 Expression may be regulated by Fur YP_002264664.1 Similar to Escherichia coli Cellulose synthase catalytic subunit BcsA UniProt:P37653 (872 aa) fasta scores: E()=1.9e-14, 26.644% id in 578 aa YP_002264671.1 CDS contains a rare Leucine start codon (CTT), or may have an alternative translational start YP_002264683.1 No significant database matches. Expression may be regulated by Fur YP_002264693.1 No significant database matches. Expression may be regulated by Fur YP_002264705.1 Similar to Actinomycetemcomitans Fimbrial protein Flp precursor UniProt:O66149 (75 aa) fasta scores: E()=0.004, 31.429% id in 70 aa YP_002264706.1 Similar to Actinomycetemcomitans TadV UniProt:Q7X0M3 (142 aa) fasta scores: E()=5.7e-07, 33.103% id in 145 aa YP_002264710.1 Similar to Actinobacillus actinomycetemcomitans pilus assembly protein tadZ UniProt:Q8GCZ9 fasta scores: E()=0.002 YP_002264711.1 Similar to Actinomycetemcomitans TadA UniProt:Q9XC06 (426 aa) fasta scores: E()=1.3e-77, 53.318% id in 422 aa YP_002264712.1 Similar to Actinomycetemcomitans TadB UniProt:Q9XC05 (295 aa) fasta scores: E()=5.3e-28, 37.000% id in 300 aa YP_002264713.1 Similar to Actinomycetemcomitans TadC UniProt:Q9S4A8 (288 aa) fasta scores: E()=7e-23, 32.667% id in 300 aa YP_002264714.1 Similar to Actinomycetemcomitans TadD UniProt:Q9S4A7 (253 aa) fasta scores: E()=7.1e-13, 30.252% id in 238 aa YP_002264715.1 Similar to Actinomycetemcomitans TadE UniProt:Q7X0L4 (191 aa) fasta scores: E()=0.75, 24.176% id in 182 aa YP_002264716.1 Similar to Actinomycetemcomitans TadF UniProt:Q9S4A5 (200 aa) fasta scores: E()=7.2e-08, 31.148% id in 183 aa YP_002264717.1 Similar to Actinomycetemcomitans TadG UniProt:Q9S4A4 (538 aa) fasta scores: E()=0.00046, 21.012% id in 514 aa YP_002264723.1 Converts glycerol and ADP to glycerol-3-phosphate and ADP YP_002264725.1 in Escherichia coli this homodimeric enzyme is expressed under aerobic conditions; anaerobic expression is repressed by the arcAB system; converts sn-glycerol-3-phosphate and ubiquinone-8 to dihydroxy acetone phosphate and ubiquinol-8; associates with the cytoplasmic membrane YP_002264731.1 Similar to Nitrosomonas europaea Cytochrome c551 peroxidase precursor Ccp UniProt:P55929 (334 aa) fasta scores: E()=7.6e-42, 42.907% id in 289 aa YP_002264732.1 anaerobic; with GlpAB catalyzes the conversion of glycerol-3-phosphate to dihydroxyacetone phosphate YP_002264733.1 sn-glycerol-3-phosphate dehydrogenase (anaerobic); catalyzes the formation of dihydroxyacetone from glycerol 3-phosphate; part of GlpABC complex; presumably this subunit is responsible for membrane interactions and contains iron-sulfur clusters YP_002264734.1 anaerobic, catalyzes the conversion of glycerol 3-phosphate to dihydroxyacetone using fumarate or nitrate as electron acceptor YP_002264735.1 Similar to Eubacterium acidaminophilum FdhA-I protein UniProt:Q93V06 (893 aa) fasta scores: E()=1.3e-116, 46.485% id in 882 aa YP_002264736.1 catalyzes the release of the N-terminal amino acid from a tripeptide YP_002264740.1 Possible alternative translational start site after codon 13 YP_002264741.1 Catalyzes the aldol condensation of glyoxylate with acetyl-CoA to form malate as part of the second step of the glyoxylate bypass and an alternative to the tricarboxylic acid cycle YP_002264751.1 Expression may be regulated by Fur YP_002264752.1 Similar to Pseudomonas fluorescens ColS protein UniProt:P95472 (425 aa) fasta scores: E()=7.6e-09, 27.469% id in 324 aa YP_002264753.1 Similar to Pseudomonas fluorescens ColR protein UniProt:P95471 (227 aa) fasta scores: E()=2.9e-33, 42.273% id in 220 aa YP_002264759.1 Similar to Cryptococcus curvatus Delta-9 fatty acid desaturase UniProt:P79078 (555 aa) fasta scores: E()=2.6e-45, 44.371% id in 302 aa YP_002264762.1 Similar to Salmonella typhimurium Outer membrane pore protein E precursor PhoE UniProt:P30705 (350 aa) fasta scores: E()=6.7e-10, 24.148% id in 352 aa YP_002264764.1 Similar to Escherichia coli Putative ATP-dependent RNA helicase RhlE UniProt:P25888 (454 aa) fasta scores: E()=1.6e-73, 55.303% id in 396 aa YP_002264767.1 Similar to Escherichia coli Secondary glycine betaine transporter BetU UniProt:Q71CH5 (667 aa) fasta scores: E()=8.2e-70, 41.667% id in 504 aa YP_002264768.1 Similar to Escherichia coli Inner membrane protein YibH UniProt:P0AFV0 (378 aa) fasta scores: E()=2.8e-58,45.000% id in 380 aa YP_002264772.1 Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction YP_002264778.1 Similar to Escherichia coli Cystine-binding periplasmic protein precursor FliY UniProt:P0AEM9 (266 aa) fasta scores: E()=8.2e-18, 31.765% id in 255 aa YP_002264781.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive YP_002264789.1 catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate YP_002264794.1 Similar to Alcaligenes xylosoxydans Cytochrome c' UniProt:P00138 (127 aa) fasta scores: E()=1.1e-10, 32.031% id in 128 aa YP_002264799.1 catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis YP_002264800.1 Expression may be stress-induced YP_002264813.1 acts together with PspC to induce psp operon during infection with phage, exposure to ethanol or osmotic shock; forms a complex with PspA and C; PspC is required for PspAB binding YP_002264815.1 Expression may be stress-induced YP_002264817.1 catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine YP_002264821.1 Similar to Bacillus subtilis Thiaminase-2 TenA UniProt:P25052 (236 aa) fasta scores: E()=5.4e-10, 28.241% id in 216 aa YP_002264822.1 catalyzes the formation of 4-methyl-5-(2-phosphoethyl)-thiazole and ADP from 4-methyl-5-(2-hydroxyethyl)-thiazole and ATP YP_002264823.1 Condenses 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate to form thiamine monophosphate YP_002264831.1 catalyzes the NADPH-dependent deamination of GMP to inosine monophosphate YP_002264832.1 Similar to Acetobacter pasteurianus ApaLI methylase UniProt:P70750 (429 aa) fasta scores: E()=2.6e-20, 29.815% id in 379 aa YP_002264833.1 Similar to Bradyrhizobium sp. btai1 ATP-binding region, ATPase-like (Fragment) UniProt:Q35DF7 (804 aa) fasta scores: E()=6.9e-52, 33.213% id in 828 aa YP_002264835.1 Similar to Vibrio phage k139 CI UniProt:Q9XJF9 (215 aa) fasta scores: E()=2.5e-10, 48.113% id in 106 aa YP_002264840.1 [Cu-Zn] YP_002264846.1 Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA YP_002264848.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase YP_002264858.1 Similar to Escherichia coli Esterase YdiI UniProt:P77781 (136 aa) fasta scores: E()=5.3e-23, 48.148% id in 135 aa. The CDS appears to be truncated at the N-terminus YP_002264862.1 Similar to Vibrio fischeri orfc668-5 (superintegron p668 insert) UniProt:Q84B85 (251 aa) fasta scores: E()=4.5e-83, 99.203% id in 251 aa YP_002264863.1 Weakly similar to Streptococcus suis seps16C UniProt:Q5H807 (362 aa) fasta scores: E()=2.6e-06, 27.711% id in 166 aa YP_002264872.1 Similar to Escherichia coli Cell filamentation protein fic UniProt:P20605 (200 aa) fasta scores: E()=2.5e-30, 43.878% id in 196 aa YP_002264878.1 No significant database matches. Expression may be regulated by Fur YP_002264888.1 CDS contains a rare Leucine start codon (TTA) YP_002264894.1 C-terminal part is similar to Escherichia coli Ribosomal large subunit pseudouridine synthase A RluA UniProt:P0AA37 (218 aa) fasta scores: E()=3e-25, 43.396% id in 212 aa. CDS is extended at the N-terminus in comparison to the Escherichia coli orthologue YP_002264895.1 C-terminal part is similar to Escherichia coli Ribosomal large subunit pseudouridine synthase A RluA UniProt:P0AA37 (218 aa) fasta scores: E()=3.1e-26, 44.292% id in 219 aa. CDS is extended at the N-terminus in comparison to the Escherichia coli orthologue YP_002264898.1 Expression may be regulated by Fur YP_002264899.1 catalyzes hydrolysis of 1,6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate; involved in murein recycling YP_002264900.1 hydrolyzes the terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides YP_002264901.1 regulates genes involved in trehalose metabolism; binds the intermediate trehalose-6-phosphate; binds a dimer; regulates treBC operon YP_002264902.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel YP_002264909.1 contains a von Willibrand factor type A domain; stimulates the ATPase activity of RavA YP_002264914.1 Expression may be stress-induced YP_002264932.1 catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers YP_002264933.1 catalyzes the formation of deamido-NAD(+) from nicotinate ribonucleotide and ATP YP_002264936.1 Expression may be stress-induced YP_002264946.1 forms a tetramer composed of 2 alpha subunits and 2 beta subunits in the inner membrane; involved in catalyzing transfer of hydride ion equivalents between NAD and NADP; stereospecific (AB-specific); functions as a proton pump by translocating protons from cytoplasm to periplasm YP_002264947.1 catalyzes reversible transfer of hydride ion equivalent between NAD and NADP; membrane-bound proton pump that translocates protons from cytosolic to periplasmic side of the inner membrane; forms a tetramer composed of two alpha and 2 beta subunits; AB-stereospecific enzyme YP_002264956.1 involved in start site selection during the initiation of translation YP_002264958.1 Similar to Selenomonas ruminantium Recombinase XerD UniProt:Q845Z5 (328 aa) fasta scores: E()=1.1e-08, 28.571% id in 287 aa YP_002264959.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli YP_002264965.1 forms a trimer; related to eukaryotic protein gephyrin; functions during molybdenum cofactor biosynthesis YP_002264968.1 Possible alternative translational start site YP_002264974.1 Similar to Escherichia coli ATP-dependent RNA helicase SrmB UniProt:P21507 (444 aa) fasta scores: E()=5.9e-47, 37.055% id in 421 aa YP_002264979.1 Expression may be stress-induced YP_002264981.1 catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate YP_002264984.1 catalyzes the formation of 2-dehydro-3-deoxy-6-phospho-D-gluconate from 6-phospho-D-gluconate YP_002264986.1 essential GTPase; functions in ribosome assembly; binds a unique part of the 23S rRNA; interacts with ribosomal protein L25(Ctc) YP_002264988.1 Expression may be regulated by Fur YP_002264992.1 Expression may be regulated by Fur YP_002264994.1 Similar to Escherichia coli Biofilm PGA synthesis N-glycosyltransferase PgaC UniProt:P75905 (441 aa) fasta scores: E()=9.6e-16, 25.234% id in 428 aa. Expression may be regulated by Fur YP_002265000.1 Similar to Escherichia coli Inner membrane protein YqjA UniProt:P0AA63 (EMBL:D13328 (220 aa) fasta scores: E()=8.8e-25, 38.967% id in 213 aa. Expression may be regulated by Fur YP_002265001.1 catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate YP_002265003.1 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate YP_002265006.1 Similar to Escherichia coli Biofilm PGA synthesis N-glycosyltransferase PgaC UniProt:P75905 (441 aa) fasta scores: E()=4.6e-16, 25.455% id in 440 aa YP_002265008.1 part of the ATP-dependent transport system LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane YP_002265016.1 Similar to C-terminal part of Aeromonas hydrophila FKBP-type peptidyl-prolyl cis-trans isomerase fkpA precursor UniProt:O08437 (268 aa) fasta scores: E()=8.3e-25, 63.158% id in 133 aa YP_002265019.1 catalyzing the hydrolysis of 4-imidazolone-5-propionate to N-formimidoyl-L-glutamate, the third step in the histidine degradation pathway YP_002265020.1 catalyzes the formation of glutamate and formamide from N-formimidoyl-L-glutamate YP_002265021.1 catalyzes the formation of 4-imidazolone-5-propanoate from urocanate during histidine metabolism YP_002265022.1 catalyzes the degradation of histidine to urocanate and ammmonia YP_002265025.1 Expression may be regulated by Fur YP_002265028.1 Similar to Escherichia coli Cation efflux system protein cusB precursor UniProt:P77239 (407 aa) fasta scores: E()=1.5e-33, 32.927% id in 410 aa YP_002265039.1 SMC (structural maintenance of chromosomes) family of proteins; involved in chromosome condensatin and partitioning; forms a homodimer and the C-terminal is essential for DNA-binding activity while the purified N-terminal domain binds FtsZ; mutations result in cell division defects YP_002265040.1 acts with MukB and MukF to condense the chromosome and allow for segregation during cell division YP_002265041.1 acts with MukB and MukE to condense the chromosome and allow for segregation during cell division YP_002265042.1 involved in cellular zinc and cadmium homeostasis by binding excess metal ions to its cysteine sulfurs and histidine nitrogens; expression of smtA in cyanobacteria is repressed by SmtB at low concentrations of zinc; NO elicits release of Zn ions from SmtA YP_002265044.1 CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS YP_002265045.1 Possible alternative translational start YP_002265046.1 transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate YP_002265047.1 involved in the transport of lipid A across the inner membrane YP_002265050.1 catalyzes the hydrolysis of pyrophosphate to phosphate YP_002265051.1 Similar to Bacteriophage P2 Replication gene A protein (GpA) UniProt:Q06419 (761 aa) fasta scores: E()=1.7e-05, 32.948% id in 173 aa YP_002265053.1 Similar to Bacteriophage L-413C Ogr UniProt:Q858U4 (99 aa) fasta scores: E()=6.8e-06, 41.429% id in 70 aa YP_002265056.1 Weakly similar to Pseudomonas phage PsP3 Late gene activator Pag UniProt:Q37973 (72 aa) fasta scores: E()=0.27, 34.783% id in 69 aa YP_002265057.1 Weakly similar to Bacteriophage HP1 Major capsid protein UniProt:P51720 (336 aa) fasta scores: E()=2e-20,28.025% id in 314 aa YP_002265069.1 Similar to Salmonella typhimurium Suppressor for copper-sensitivity B precursor ScsB UniProt:O33918 (627 aa) fasta scores: E()=6.7e-55, 38.657% id in 670 aa YP_002265070.1 Similar to Salmonella typhimurium Suppressor for copper-sensitivity D ScsD UniProt:O33920 (168 aa) fasta scores: E()=3.3e-20, 36.145% id in 166 aa YP_002265071.1 Similar to Salmonella typhimurium Suppressor for copper-sensitivity C precursor ScsC UniProt:O33919 (207 aa) fasta scores: E()=2.8e-10, 38.136% id in 118 aa YP_002265074.1 part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor YP_002265075.1 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine YP_002265084.1 Expression may be regulated by Fur YP_002265087.1 manganese-dependent 5'-nucleotidase; specific for 5'-UMP, 5'-dUMP, and 5'-dTMP; member of haloacid dehalogenase (HAD)-like hydrolase superfamily YP_002265088.1 Part of the ABC transporter complex modABC involved in molybdenum import YP_002265089.1 part of ModCBA molybdate transporter; member of ABC superfamily; inner membrane component; regulated by repressor protein ModE YP_002265091.1 catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation YP_002265094.1 CDS contains a rare Leucine start codon (TTA) YP_002265095.1 Similar to Escherichia coli Lytic transglycosylase Slt70 (PDB 1QSA), evalue=4e-09 identity=(49, 166) YP_002265097.1 catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate YP_002265098.1 activates anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions YP_002265099.1 Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates YP_002265106.1 Possible alternative translational start site after codon 21 YP_002265117.1 Possible alternative translational start site after codon 13 YP_002265118.1 catalyzes the formation of phosphonoacetaldehyde from 2-aminoethylphosphonate and pyruvate YP_002265119.1 catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate YP_002265120.1 catalyzes the degradation of phosphonoacetaldehyde to acetaldehyde and phosphate YP_002265125.1 proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichia coli this protein self regulates transcription via a DNA-binding domain at the N-terminus but the proteins from this group do not and in addition appear to have a truncated C-terminal domain YP_002265130.1 membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr YP_002265131.1 Similar to Escherichia coli Mannitol-specific cryptic phosphotransferase enzyme IIA component UniProt:P69824 (147 aa) fasta scores: E()=9.9e-12, 36.913% id in 149 aa YP_002265138.1 CDS contains a rare Leucine start codon (TTA) YP_002265139.1 catalyzes the formation of 2-amino-3-oxobutanoate from acetyl-CoA and glycine YP_002265140.1 converts threonine and NAD to 1,2-amino-3-oxobutanoate and NADH; functions in threonine catabolism YP_002265143.1 Expression may be regulated by Fur; Similar to Vibrio fischeri (strain ATCC 700601/ES114) atp-dependent protease la (ec 3.4.21.53). UniProt:Q5E0G2 (EMBL:CP000021) (776 aa) fasta scores: E()=0, 85.8% id in 776 aa YP_002265159.1 DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium YP_002265161.1 catalyzes the formation of 8-amino-7-oxononanoate from 6-carboxyhexanoyl-CoA and L-alanine YP_002265163.1 catalyzes the formation of S-adenosyl-4-methylthionine-2-oxobutanoate and 7,8-diaminononanoate from S-adenosyl-L-methionine and 8-amino-7-oxononanoate YP_002265166.1 Similar to Enterobacter agglomerans Transcriptional regulatory protein TyrR UniProt:Q9ZIB7 (521 aa) fasta scores: E()=3.7e-92, 49.516% id in 517 aa YP_002265168.1 Similar to Vibrio cholerae Deoxyribodipyrimidine photo-lyase PhrA UniProt:Q9KNA8 (469 aa) fasta scores: E()=1.5e-94, 49.364% id in 472 aa YP_002265170.1 Expression may be regulated by Fur YP_002265179.1 Similar to Serratia liquefaciens BsmA UniProt:Q71BC1 (214 aa) fasta scores: E()=3.4e-46, 59.048% id in 210 aa YP_002265180.1 Similar to Escherichia coli Multidrug resistance protein D EmrD UniProt:P31442 (394 aa) fasta scores: E()=3.4e-24, 30.709% id in 381 aa YP_002265181.1 Similar to Escherichia coli HTH-type transcriptional activator AaeR UniProt:P67662 (309 aa) fasta scores: E()=1.9e-22, 34.899% id in 298 aa YP_002265193.1 Similar to Xanthomonas campestris pv. campestris PTS system fructose-specific EIIBC component FruA UniProt:P23355 (580 aa) fasta scores: E()=6.5e-53, 41.807% id in 476 aa YP_002265196.1 Similar to Escherichia coli Fructose-like phosphotransferase enzyme IIB component 2 FrwB UniProt:P69816 (106 aa) fasta scores: E()=8.7e-11, 46.316% id in 95 aa YP_002265203.1 part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter involved in the high-affinity transport of Fe(3+)-ferrichrome YP_002265205.1 Expression may be regulated by Fur YP_002265215.1 with MalKFE is involved in the transport of maltose into the cell YP_002265217.1 Expression may be regulated by Fur YP_002265218.1 AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA YP_002265224.1 polymerizes uridine 5'-diphosphate glucose to cellulose; acts with BcsB, BcsZ and BcsC in cellulose biosynthesis YP_002265237.1 No significant database matches. Expression may be stress-induced YP_002265248.1 NAD(P)H-flavin reductase; catalyzes the reversible oxidation/reduction of NAD(P) and flavine mononucleotide; in Salmonella and E. coli this protein also reduces aquacob(III)alamin to cob(II)alamin YP_002265252.1 part of the fatty acid reductase system required for aldehyde biosynthesis; produces fatty acids for the luminescent reaction YP_002265264.1 alpha-aspartyl dipeptidase; catalyzes the hydrolysis of dipeptides with an N-terminal aspartate residue; belongs to peptidase S51 family YP_002265270.1 Expression may be regulated by Fur YP_002265280.1 Similar to Bacillus subtilis Phosphotransferase system (PTS) fructose-specific enzyme IIAB component FruA UniProt:P71012 (635 aa) fasta scores: E()=6.7e-11, 37.500% id in 144 aa YP_002265281.1 Possible alternative translational start site after codon 12 YP_002265285.1 Similar to Bacillus ps3 Sodium/proton-dependent alanine carrier protein Acp UniProt:P30145 (445 aa) fasta scores: E()=1.6e-52, 50.759% id in 461 aa YP_002265289.1 Expression may be stress-induced YP_002265291.1 Similar to Salmonella choleraesuis Putative POT family, peptide transport protein YdgR UniProt:Q57PI5 (501 aa) fasta scores: E()=1.2e-18, 20.896% id in 469 aa YP_002265300.1 Similar to Escherichia coli Inner membrane protein YddG UniProt:P46136 (274 aa) fasta scores: E()=2.9e-47,48.897% id in 272 aa YP_002265301.1 Expression may be regulated by Fur YP_002265303.1 Similar to Bacillus subtilis Probable 6-phospho-beta-glucosidase LicH UniProt:P46320 (442 aa) fasta scores: E()=1.1e-82, 48.526% id in 441 aa YP_002265304.1 Similar to Escherichia coli HTH-type transcriptional regulator DsdC UniProt:P46068 (311 aa) fasta scores: E()=5.7e-32, 36.877% id in 301 aa YP_002265305.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_002265313.1 Expression may be regulated by Fur YP_002265314.1 Expression may be regulated by Fur YP_002265315.1 Similar to Escherichia coli Small-conductance mechanosensitive channel MscS UniProt:Q2M9R8 (286 aa) fasta scores: E()=5.4e-26, 33.457% id in 269 aa YP_002265316.1 Similar to Vibrio fischeri Hypothetical protein. UniProt:Q5DYG8 (173 aa) fasta scores: E()=2.3e-39, 83.333% id in 132 aa. The CDS appears to be truncated at the N-terminus YP_002265320.1 Similar to Klebsiella aerogenes Leucine-responsive regulatory protein Lrp UniProt:P0A2S1 (163 aa) fasta scores: E()=9.4e-15, 38.462% id in 143 aa YP_002265327.1 Expression may be regulated by Fur YP_002265332.1 Similar to Thermoanaerobacter brockii NADH oxidase UniProt:P32382 (651 aa) fasta scores: E()=1.8e-34, 36.103% id in 349 aa YP_002265336.1 Expression may be regulated by Fur YP_002265340.1 catalyzes the uptake of putrescine via a proton symport mechanism, as well as the efflux of putrescine by a putrescine/ornithine antiport system YP_002265347.1 Similar to Yersinia enterocolitica Hemin permease HemU UniProt:P74980 (334 aa) fasta scores: E()=4.5e-34,42.160% id in 287 aa YP_002265348.1 Similar to Pseudomonas aeruginosa ATPase component (Probable ATP-binding component of ABC transporter) PhuV UniProt:O68877 (255 aa) fasta scores: E()=2.1e-23, 37.209% id in 258 aa YP_002265350.1 NADPH-dependent; oxygen-insensitive; catalyzes the reduction of nitroaromatic compounds YP_002265364.1 Similar to Bordetella pertussis CyaB UniProt:P18770 (712 aa) fasta scores: E()=5.1e-51, 30.273% id in 697 aa YP_002265366.1 Expression may be regulated by Fur YP_002265369.1 Similar to Yersinia pestis Plasmid partitioning control protein SopB UniProt:O68706 (320 aa) fasta scores: E()=3.4e-14, 32.273% id in 220 aa YP_002265370.1 Similar to Proteus vulgaris ParA UniProt:Q8L255 (401 aa) fasta scores: E()=2.4e-25, 29.412% id in 391 aa YP_002265373.1 Similar to Escherichia coli Resolvase parA UniProt:P22996 (219 aa) fasta scores: E()=1.6e-17, 38.308% id in 201 aa YP_002265375.1 Similar to Vibrio fischeri Hypothetical protein UniProt:Q5DYK6 (80 aa) fasta scores: E()=1.7e-22, 76.923% id in 78 aa. Orthologues are identified on chromosomal DNA in other vibrios YP_002265383.1 Similar to Bacteriophage phi-80 Repressor protein CI UniProt:P14819 (235 aa) fasta scores: E()=1.5e-07,29.060% id in 234 aa YP_002265387.1 Identical to Aliivibrio salmonicida Plasmid pVS43 Putative transposase UniProt:Q5EJX2 (359 aa) fasta scores: E()=2.3e-156, 99.721% id in 359 aa YP_002265389.1 CDS contains a rare Valine start codon (GTA) YP_002265393.1 Weakly similar to Enterococcus faecium Transposase for transposon Tn1546 UniProt:Q06238 (988 aa) fasta scores: E()=5.5e-41, 25.488% id in 1024 aa YP_002265394.1 Identical to Aliivibrio salmonicida Plasmid pVS43 Putative transposase UniProt:Q5EJX2 (359 aa) fasta scores: E()=2.3e-156, 99.721% id in 359 aa YP_002265395.1 Experimentally shown to be regulated by iron. Predicted Fur boxes indicate direct Fur regulation YP_002265396.1 Similar to Gluconacetobacter diazotrophicus ABC-type Fe3+ transport system permease component FeuB UniProt:Q288C8 (342 aa) fasta scores: E()=1.8e-30, 37.771% id in 323 aa YP_002265400.1 Weakly similar to Plasmid ColIb-P9 Replication initiation protein RepZ UniProt:Q7DJZ7 (343 aa) fasta scores: E()=0.06, 24.111% id in 253 aa YP_002265401.1 Similar to Escherichia coli MobC-like protein UniProt:Q6XGE7 (248 aa) fasta scores: E()=0.0018, 25.692% id in 253 aa YP_002265402.1 Weakly similar to Salmonella typhimurium O-antigen acetylase OafA UniProt:P74874 (609 aa) fasta scores: E()=6.3e-54, 33.591% id in 646 aa YP_002265404.1 Weakly similar to Bacteriophage Sf6 O-acetyl transferase UniProt:P23214 (333 aa) fasta scores: E()=4.2e-11, 28.614% id in 339 aa