-- dump date 20140618_193601 -- class Genbank::CDS -- table cds_note -- id note YP_691721.1 identified by match to PFAM protein family HMMPF03969 and KEGG dnaA in multiple genomes. InterPro: Bacterial chromosomal replication initiator protein DnaA; High confidence in function and specificity YP_691722.1 identified by sequence similarity; High confidence in function and specificity YP_691723.1 identified by sequence similarity; InterPro: RecF protein; Hypothetical protein YP_691724.1 identified by sequence similarity; InterPro: DNA topoisomerase II; High confidence in function and specificity YP_691725.1 (type IV pili sensor histidine kinase/responseregulator PilL/ChpA fusion protein) identified by match to TIGR protein family HMMTIGR01387 InterPro: H-NS histone family; Family membership YP_691726.1 identified by sequence similarity; High confidence in function and specificity YP_691727.1 identified by sequence similarity; identified by match to TIGRFAM protein family HMMTIGR00213; Function unclear YP_691728.1 (glycyl-tRNA synthetase tetrameric type betasubunit) identified by match to TIGR protein family HMMTIGR00211 InterPro: Glycyl-tRNA synthetase beta subunit; High confidence in function and specificity YP_691729.1 glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_691730.1 identified by sequencesimilarity; InterPro: DNA-3-methyladenine glycosylase I; High confidence in function and specificity YP_691734.1 transcriptional regulator MarR family identified by sequencesimilarity; InterPro: Bacterial regulatory protein MarR family; Family membership YP_691735.1 inner membrane protein as shown by TMHMM hits YP_691736.1 identified by sequence similarity YP_691737.1 Family membership YP_691739.1 transcriptional regulator (AraC family) identified by match to PFAM protein family HMMPF00165 InterPro: AraC type helix-turn-helix; High confidence in function and specificity YP_691740.1 (methylmalonate semialdehyde dehydrogenase) identified by sequence similarity; InterPro: Aldehyde dehydrogenase family distal valine metabolic pathway; High confidence in function and specificity YP_691741.1 identified by sequencesimilarity; InterPro: Acyl-CoA dehydrogenase; Family membership YP_691742.1 identified by sequence similarity; High confidence in function and specificity YP_691743.1 conserved hypothetical protein; Family membership YP_691744.1 identified by Glimmer2; has high similarity to PP0135 YP_691745.1 conserved hypothetical protein identified by sequence similarity; InterPro: DUF209; Family membership YP_691746.1 glutathione S-transferase domain protein identified by match to PFAM protein family HMMPF00043 InterPro: Glutathione S-transferase C terminus; Family membership YP_691747.1 (acyl carrier protein phosphodiesterase ) identified by sequencesimilarity; High confidence in function and specificity YP_691748.1 transcriptional regulator LysR family identified by match to PFAM protein family HMMPF03466 InterPro: Bacterial regulatory protein LysR family; High confidence in function and specificity YP_691750.1 sensor histidine kinase identified by sequence similarity; InterPro: Histidine kinase C-terminal; High confidence in function and specificity YP_691751.1 probable 2-component transcription regulator identified by match to TIGR protein family HMMTIGR01387 InterPro: Response regulator receiver domain; High confidence in function and specificity YP_691752.1 identified by sequence similarity. InterPro: Thioredoxin YP_691753.1 identified by sequencesimilarity; High confidence in function and specificity YP_691754.1 identified by sequencesimilarity; InterPro: Dihydroorotase multifunctional complex type; Hypothetical protein YP_691755.1 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis YP_691756.1 identified by sequence similarity; High confidence in function and specificity YP_691757.1 Cytochrome b561 family; Family membership YP_691760.1 conserved hypothetical protein YP_691762.1 Family membership YP_691763.1 (lipase/esterase family protein) identified by sequence similarity; InterPro: Esterase/lipase/thioesterase/carboxlesterase family active site; High confidence in function and specificity YP_691764.1 AhpC/TSA family protein identified by sequencesimilarity; Family membership YP_691765.1 Hypothetical protein YP_691766.1 uncharacterized protein containing a von Willebrand factor type (vWA) domain identified by match to PFAM protein family HMMPF00092 InterPro: von Willebrand factor type A domain; Family membership YP_691768.1 nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ; the YajQ protein from Pseudomonas synringae appears to play a role in activation of bateriophage phi6 segment L transcription YP_691771.1 Catalyzes the transfer of the ammonia group from glutamine to a new carbon-nitrogen group YP_691773.1 (conserved hypothetical protein homologous to acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase) identified by match to PFAM protein family HMMPF00132 InterPro: Bacterial transferase hexapeptide repeat; Family membership YP_691774.1 transcriptional regulator TetR family identified by sequencesimilarity; InterPro: Bacterial regulatory proteins TetR family; Family membership YP_691775.1 acyltransferase identified by match to PFAM protein family HMMPF04241 InterPro: Phospholipid and glycerol acyltransferase (from motifs_6.msf); Family membership YP_691778.1 Cytochrome b561 family membership YP_691779.1 peptidyl-tRNA hydrolase domain protein identified by sequence similarity; InterPro: Class I peptide chain release factor; Family membership YP_691781.1 zinc-containing 'long-chain' alcohol dehydrogenases identified by sequencesimilarity; Family membership YP_691784.1 hemerythrin-like protein (family member ship) identified by sequencesimilarity; InterPro: Hemerythrin; Family membership YP_691786.1 fumarylacetoacetate hydrolase family protein) identified by match to PFAM protein family HMMPF01557 InterPro: Fumarylacetoacetate (FAA) hydrolase family; Family membership YP_691787.1 oxidoreductase FAD-binding identified by match to TIGR protein family HMMTIGR01679 InterPro: FAD linked oxidase C-terminal; Function unclear YP_691788.1 catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate YP_691789.1 conserved hypothetical protein belongs to the family DUF394 (protein of unknown function) identified by sequence similarity; InterPro: TPR repeat YP_691793.1 Region start changed from 77784 to 77655 (-129 bases) regional start was changed to be in accordance with the results of the observations. YP_691794.1 identified by sequence similarity; Family membership YP_691795.1 identified by sequence similarity; InterPro: Na+/H+ exchanger; High confidence in function and specificity YP_691796.1 outer membrane ferric siderophore receptor identified by sequencesimilarity; InterPro: TonB-dependent receptor protein; High confidence in function and specificity YP_691799.1 acyltransferase transferring groups other than amino-acyl groups; Specificity unclear YP_691800.1 identified by sequence similarity; identified by match to PFAM protein family HMMPF01019 InterPro: Gamma-glutamyltranspeptidase; High confidence in function and specificity YP_691801.1 identified by match to TIGR protein family HMMTIGR00482 InterPro: Cytidylyltransferase; High confidence in function and specificity YP_691802.1 truncated transposase OrfA identified by match to PFAM protein family HMMPF04218; Family membership YP_691803.1 transposase identified by match to PFAM protein family HMMPF00665; InterPro: Integrase catalytic core; Family membership YP_691805.1 identified by sequence similarity; identified by match to PFAM protein family HMMPF00732; InterPro: Glucose-methanol-choline (GMC) oxidoreductase; Family membership YP_691807.1 Alcanivorax borkumensis aldehyde dehydrogenase,; Specificity unclear YP_691808.1 phaD, transcriptional regulator TetR family InterPro: Bacterial regulatory proteins TetR family; High confidence in function and specificity YP_691809.1 (hydrolase alpha/beta fold family) identified by match to TIGR protein family HMMTIGR01250 InterPro: Esterase/lipase/thioesterase family active site enzymes of the alpha/beta fold enzymes operate on substrates with different chemical composition in various biological contexts; Family membership YP_691811.1 Conserved hypothetical protein YP_691812.1 High confidence in function and specificity YP_691813.1 (transcriptional regulator AraC family) identified by match to PFAM protein family HMMPF00165 InterPro: ThiJ/PfpI family Transcription regulation; DNA-binding; Family membership YP_691814.1 conserved hypothetical protein; Function unclear YP_691815.1 identified by sequencesimilarity; InterPro: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Hypothetical protein YP_691816.1 SPFH domain/Band 7 family protein identified by sequence similarity; InterPro: Band 7 protein; Family membership YP_691817.1 Hypothetical protein YP_691818.1 (slyD) (peptidyl-prolyl cis-trans isomerase FKBP-type) identified by sequence similarity; InterPro: FKBP-type peptidyl-prolyl cis-trans isomerase (PPIase); Specificity unclear YP_691819.1 cytochrome B651, Pfam: Ni_hydr_CYTB; Family membership YP_691820.1 lipid A biosynthesis lauroyl acyltransferase identified by sequence similarity; High confidence in function and specificity YP_691821.1 conserved hypothetical protein YP_691822.1 (chemotaxis protein, ), pfam01584, CheW, CheW-like domain.; Conserved hypothetical protein YP_691823.1 (protein-glutamate methylesterase CheB) identified by sequencesimilarity; InterPro: CheB methylesterase; High confidence in function and specificity YP_691824.1 ChpA two-component hybrid sensor and regulator, identified by match to TIGR protein family HMMTIGR01387 InterPro: Histidine kinase C-terminal still frameshift probable component of chemotactic signal transduction system; Specificity unclear YP_691825.1 (methyltransferase CheR-like) identified by match to PFAM protein family HMMPF00515; High confidence in function and specificity YP_691826.1 Methyl-accepting chemotaxis protein (MCP) signaling domain; Specificity unclear YP_691827.1 identified by match to PFAM protein family HMMPF01584 InterPro: CheW-like domain; High confidence in function and specificity YP_691828.1 identified by sequence similarity; InterPro: Response regulator receiver domain; High confidence in function and specificity YP_691829.1 identified by sequencesimilarity; InterPro: Response regulator receiver domain; High confidence in function and specificity YP_691830.1 identified by match to TIGR protein family HMMTIGR01380 InterPro: Prokaryotic glutathione synthetase ATP-binding domain; High confidence in function and specificity YP_691831.1 Periplasmic protein TonB, links inner and outer membranes; Family membership YP_691832.1 (alginate biosynthesis nucleoside diphosphatekinase regulator AlgH) identifiedby sequence similarity; Family membership YP_691833.1 Predicted endonuclease involved in recombination, possible Holliday junction resolvase; Family membership YP_691834.1 (conserved hypothetical protein) identified by match to PFAM protein family HMMPF04; sterol desaturase family protein; Family membership YP_691835.1 transcriptional regulator AraC family identified by match to PFAM protein family HMMPF00165 InterPro: AraC type helix-turn-helix; Family membership YP_691836.1 esterase, , identified by match to PFAM protein family HMMPF00756 InterPro: esterase; Family membership YP_691837.1 adhC; alcohol dehydrogenase class III, formaldehyde dehydrogenase hydroxyacid dehydrogenase family protein identified by match to TIGR protein family HMMTIGR01751 InterPro: Zinc-containing alcohol dehydrogenase superfamily; High confidence in function and specificity YP_691838.1 transcriptional regulator LysR family identified by match to PFAM protein family HMMPF03466 InterPro: Bacterial regulatory protein LysR family; Family membership YP_691839.1 Family membership YP_691840.1 catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia YP_691841.1 transcriptional regulator GntR family identified by match to PFAM protein family HMMPF00392 InterPro: Bacterial regulatory proteins GntR family; Specificity unclear YP_691842.1 High confidence in function and specificity YP_691843.1 Family membership YP_691844.1 identified by match to PFAM protein family HMMPF02753 and sequence similarity; Specificity unclear YP_691845.1 identified by match to PFAM protein family HMMPF00577 InterPro: Fimbrial biogenesis outer membrane usher protein; Specificity unclear YP_691846.1 (Type-1 fimbrial protein, A chain precursor) identified by match to PFAM protein family HMMPF03797 and sequence similarity; High confidence in function and specificity YP_691847.1 identified by match to PFAM protein family HMMPF03631 InterPro: Cation transport protein; Family membership YP_691848.1 involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain YP_691849.1 (sun) (sun protein, ) identified by match to PFAM protein family HMMPF01189 InterPro: Sun protein; Family membership YP_691850.1 identified by sequencesimilarity; InterPro: Methionyl-tRNA formyltransferase; High confidence in function and specificity YP_691851.1 (polypeptide deformylase) identified by match to TIGR protein family HMMTIGR00079 InterPro: Formylmethionine deformylase; High confidence in function and specificity YP_691852.1 Region start changed from 142733 to 142994 (-261 bases) YP_691853.1 (peptide deformylase)(smf family protein; DNA processing protein, DprA, ) identified by sequence similarity; InterPro: SMF family; Family membership YP_691854.1 identified by match to TIGR protein family HMMTIGR00057 InterPro: Sua5/YciO/YrdC/YwlC protein family; Family membership YP_691855.1 catalyzes the conversion of the propionic acid groups of rings I and III to vinyl groups during heme synthesis YP_691856.1 identified by sequence similarity; identified by match to PFAM protein family HMMPF01488 and TIGRFAM protein family HMMTIGR00507 InterPro: Shikimate / quinate 5-dehydrogenase; High confidence in function and specificity YP_691857.1 (conserved hypothetical protein, Kef-type K+ transport systems, predicted NAD-binding component) identified by sequencesimilarity; InterPro: Potassium channel; Family membership YP_691858.1 (Uncharacterized protein conserved in bacteria, COG3528) YP_691859.1 identified by sequencesimilarity; InterPro: Bacterial transferase hexapeptide repeat; Family membership YP_691860.1 identified by sequence similarity; identified by match to PFAM protein family HMMPF01432 InterPro: Peptidase family M3; High confidence in function and specificity YP_691863.1 Predicted metal-dependent hydrolase; identified by match to PFAM protein family HMMPF00892 YP_691864.1 transcriptional regulator, AraC family; Family membership YP_691865.1 High confidence in function and specificity YP_691866.1 identified by match to PFAM protein family HMMPF03466 InterPro: Bacterial regulatory protein LysR family; Family membership YP_691867.1 (cobalamin (5-phosphate) synthase) identified by sequence similarity; InterPro: Cobalamin-5-phosphate synthase CobS; High confidence in function and specificity YP_691868.1 (enoyl-CoA hydratase/isomerase family protein, ) identified by match to PFAM protein family HMMPF00378 InterPro: Enoyl-CoA hydratase/isomerase; High confidence in function and specificity YP_691873.1 cold-shock domain family protein identified by sequence similarity; InterPro: Cold-shock DNA-binding domain; Family membership YP_691875.1 Periplasmic solute binding protein.identified by sequence similarity; Conserved hypothetical protein YP_691876.1 ABC-type Mn/Zn transport systems, ATPase component, ABC transporter related, ABC transporter, ABC_phnC: phosphonate ABC transporter, ATP-binding protein; High confidence in function and specificity YP_691877.1 (zinc ABC transporter permease protein ZnuB) identified by match to PFAM protein family HMMPF01032 InterPro: ABC 3 transport family; Family membership YP_691878.1 (MATE efflux family protein, ) identified by match to PFAM protein family HMMPF04235 InterPro: Uncharacterized domain UPF0013; Family membership YP_691879.1 conserved hypotetical protein contains GGDEF domain YP_691880.1 (Outer membrane lipoprotein LolB, ) identified by sequence similarity; Family membership YP_691882.1 (NAD(FAD)-dependent dehydrogenases) identified by match to TIGR protein family HMMTIGR01508 InterPro: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Specificity unclear YP_691883.1 (rubredoxin/rubredoxin reductase) identified by sequence similarity; InterPro: Rubredoxin-type Fe(Cys)4 protein Rubredoxin; High confidence in function and specificity YP_691884.1 (chorismate lyase, ) identified by sequencesimilarity; Family membership YP_691885.1 (UbiA prenyltransferase family, including 4-hydroxybenzoate polyprenyl transferase, 4-hydroxybenzoate-octaprenyl transferase and related prenyltransferases) identified by sequencesimilarity; InterPro: UbiA prenyltransferase; Family membership YP_691886.1 (DNA-binding response regulator PhoB) identified by sequence similarity; High confidence in function and specificity YP_691887.1 (sensory box histidine kinase PhoR) identified by sequence similarity; InterPro: Histidine kinase C-terminal; High confidence in function and specificity YP_691888.1 identified by sequencesimilarity; InterPro: ATP-dependent DNA helicase RecG; High confidence in function and specificity YP_691889.1 Hydrogen peroxide-inducible genes activator (Morphology and auto-aggregation control protein). (transcriptional regulator LysR family) identified by match to PFAM protein family HMMPF03466; High confidence in function and specificity YP_691891.1 (phosphoribosylaminoimidazole carboxylase, catalytic subunit) identified by match to PFAM protein family HMMPF00731 InterPro: 1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase; High confidence in function and specificity YP_691892.1 (phosphoribosylaminoimidazole carboxylase ATPasesubunit) identified by match to TIGR protein family HMMTIGR01142 InterPro: ATP-grasp domain; High confidence in function and specificity YP_691894.1 conserved hypothetical protein, Similar to pspto3478 from Pseudomonas syringae (pv. tomato) YP_691895.1 Endoribonuclease L-PSP identified by sequencesimilarity; InterPro: YER057c/YjgF/UK114 family; Family membership YP_691896.1 (relA) (GTP pyrophosphokinase) identified by match to PFAM protein family HMMPF02824 InterPro: RelA/SpoT family protein; High confidence in function and specificity YP_691897.1 (DNA-directed RNA polymerase, omega subunit) identified by sequence similarity; High confidence in function and specificity YP_691898.1 identified by sequence similarity; InterPro: Guanylate kinase; High confidence in function and specificity YP_691899.1 predicted deacylase YP_691900.1 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis YP_691901.1 predicted metal-dependent hydrolase YP_691904.1 identified by match to TIGR protein family HMMTIGR01734; High confidence in function and specificity YP_691905.1 identified by match to PFAM protein family HMMPF02770 InterPro: Acyl-CoA dehydrogenase; Hypothetical protein YP_691906.1 identified by sequencesimilarity InterPro: Acyl-CoA dehydrogenase; High confidence in function and specificity YP_691907.1 oxidoreductase GMC family identified by sequencesimilarity; InterPro: Glucose-methanol-choline (GMC) oxidoreductase; Family membership YP_691908.1 predicted metal-dependent hydrolase; Conserved hypothetical protein YP_691909.1 oxidoreductase short chaindehydrogenase/reductase family identified by sequence similarity; InterPro: Short-chain dehydrogenase/reductase (SDR) superfamily; Family membership YP_691910.1 (monooxygenase flavin-binding family) identified by sequence similarity; InterPro: Flavin-containing monooxygenase (FMO); Family membership YP_691911.1 identified by match to TIGR protein family HMMTIGR01738 InterPro: Alpha/beta hydrolase fold; Family membership YP_691914.1 monooxygenase flavin-binding family (oxydoreductase with NADH or NADPH as one donor, and incorporation of one atom of oxygen) identified by sequence similarity; InterPro: Flavin-containing monooxygenase (FMO); Conserved hypothetical protein YP_691915.1 (lipase/esterase family protein) identified by sequence similarity; InterPro: Esterase/lipase/thioesterase/carboxylesterase family active site; High confidence in function and specificity YP_691916.1 oxidoreductase short chaindehydrogenase/reductase family identified by match to TIGR protein family HMMTIGR01500 InterPro: Short-chain dehydrogenase/reductase (SDR) superfamily; Conserved hypothetical protein YP_691917.1 predicted metal-dependent hydrolase; Conserved hypothetical protein YP_691918.1 transcriptional regulator, TetR family; Family membership YP_691919.1 transcriptional regulator, AraC family; Family membership YP_691920.1 identified by sequencesimilarity; InterPro: Ferredoxin; Family membership YP_691921.1 (oxidoreductase cytochrome p450 family protein) (acting on paired donors with incorporation of molecular oxygen) identified by sequencesimilarity; High confidence in function and specificity YP_691922.1 Alcohol dehydrogenase, GMC-oxidoreductase; FAD flavoprotein oxidoreductase; Choline dehydrogenase (CHD) (CDH); High confidence in function and specificity YP_691923.1 oxidoreductase, GB:L19299 SP:P41131 PID:304015GB:X59066 GB:X65460 GB:D28126 GB:D14710 SP:P25705PID:28938 PID:34468 PID:559317 and PID:559325;identified by sequence similarity; Family membership YP_691926.1 identified by sequencesimilarity; InterPro: 3 exoribonuclease family; High confidence in function and specificity YP_691927.1 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate YP_691929.1 FtsZ binding protein; synthetically lethal with a defect in the Min system; this protein is the first identified nucleoid occlusion factor which works along with the Min system to properly position the FtsZ ring assembly YP_691930.1 (acetylglutamate kinase, N-acetyl-L-glutamate-5-phosphotransferase) identified by sequence similarity; identified by match to TIGRFAM protein family HMMTIGR00761; InterPro: Acetylglutamate kinase; High confidence in function and specificity YP_691931.1 identified by sequence similarity; InterPro: Phosphoglucomutase and phosphomannomutase family; High confidence in function and specificity YP_691932.1 identifiedby sequence similarity; InterPro: dUTPase; Family membership YP_691933.1 catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, which is then decarboxylated to form 4'-phosphopantotheine YP_691934.1 (DNA repair protein (family RadC)) identified by sequencesimilarity; InterPro: DNA repair protein radC family; High confidence in function and specificity YP_691935.1 identified by sequencesimilarity; InterPro: Ribosomal protein L28; Function unclear YP_691936.1 identified by sequencesimilarity; InterPro: Ribosomal protein L33; Function unclear YP_691939.1 Bacterial type II and III secretion system protein family membership YP_691941.1 Type II/IV secretion system protein family; Family membership YP_691947.1 (transposase, ) identified by match to PFAM protein family HMMPF04218; High confidence in function and specificity YP_691949.1 (gloxalase/bleomycin resistance family protein ) identified by sequence similarity; identified by match to PFAM protein family HMMPF00903 InterPro: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Family membership YP_691950.1 glutathione S-transferase family protein identified by sequencesimilarity; InterPro: Glutathione S-transferase N terminus; Family membership YP_691952.1 (choline/carnitine/betaine transporter familyprotein) identified by match to PFAM protein family HMMPF02028 InterPro: BCCT transporter; High confidence in function and specificity YP_691954.1 OmpA family protein identified by match to PFAM protein family HMMPF00691; Function unclear YP_691957.1 identified by sequencesimilarity YP_691958.1 Specificity unclear YP_691959.1 Function unclear YP_691964.1 transcriptional regulator MerR family identified by match to PFAM protein family HMMPF00376 InterPro: Bacterial regulatory proteins MerR family; Function unclear YP_691965.1 cobalt/cadmium/zinc transporter CDF family, identified by sequencesimilarity; InterPro: Cation efflux family; Family membership YP_691968.1 ABC export system membrane fusion protein identified by sequencesimilarity; InterPro: HlyD family secretion protein; Function unclear YP_691969.1 (ABC transporter, ATP-binding protein/permease, ) identified by match to TIGR protein family HMMTIGR01740; Family membership YP_691970.1 outer membrane protein identified by sequence similarity; InterPro: Outer membrane efflux protein; Function unclear YP_691971.1 deacetylase family protein identified by sequence similarity; InterPro: Histone deacetylase family; Family membership YP_691973.1 identified by sequence similarity; High confidence in function and specificity YP_691974.1 (ABC transporter ATP-binding protein, permease, ) identified by sequencesimilarity; InterPro: AAA ATPase superfamily; Family membership YP_691976.1 aminotransferase class III identified by sequencesimilarity; InterPro: Aminotransferase class-III pyridoxal-phosphate; High confidence in function and specificity YP_691978.1 (fklB-2) (peptidyl-prolyl cis-trans isomerase FKBP-type) identified by sequencesimilarity; InterPro: Domain amino terminal to FKBP-type peptidyl-prolyl isomerase; Function unclear YP_691979.1 binds specifically to the major sigma factor sigma 70; active in stationary phase YP_691980.1 membrane protein of LrgB-like family identified by sequencesimilarity; Function unclear YP_691982.1 DsbB family protein identified by sequencesimilarity; InterPro: Disulfide bond formation protein DsbB; Specificity unclear YP_691983.1 (glutamate-cysteine ligase) identified by sequence similarity; High confidence in function and specificity YP_691984.1 S1 RNA binding domain protein identified by match to PFAM protein family HMMPF00575; Function unclear YP_691985.1 (PilH; regulatory protein pilH family) identified by sequence similarity; InterPro: Response regulator receiver domain; Family membership YP_691986.1 (cation multi-drug efflux pump, Transporter of the RND family of multidrug efflux pump, ) identified by match to PFAM protein family HMMPF04165 InterPro: Acriflavin resistance protein; Family membership YP_691987.1 secreted protein; Function unclear YP_691988.1 part of two-component system EnvZ/OmpR; regulates transcription of outer membrane porin genes ompC/F; under high osmolarity EnvZ functions as kinase/phosphotransferase and phosphorylates OmpR; the result is increased expression of ompC and repression of ompF; also functions in regulation of other genes; forms dimers upon phosphorylation YP_691989.1 (ompB), (perA), (tpo). Osmolarity sensor protein EnvZ, protein histidine kinase/phosphatase sensor for OmpR, modulatesexpression of ompF and ompC) identified by match to PFAM protein family HMMPF02518 InterPro: Histidine kinase C-terminal; High confidence in function and specificity YP_691990.1 murein hydrolase B (hydrolysing O- and S-glycosyl compounds) identified by match to PFAM protein family HMMPF01471 InterPro: peptidoglycan binding domain 1; Specificity unclear YP_691991.1 (trkA) identified by match to PFAM protein family HMMPF02080 InterPro: KTN NAD-binding domain; Family membership YP_691992.1 potassium uptake protein TrkH family identified by match to PFAM protein family HMMPF04247 InterPro: Cation transport protein; Family membership YP_691993.1 identified by match to PFAM protein family HMMPF03631 InterPro: Ribonuclease BN; Family membership YP_691994.1 identified by sequence similarity; InterPro: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; High confidence in function and specificity YP_691995.1 PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP YP_691996.1 identified by match to PFAM protein family HMMPF01430 InterPro: Hsp33 protein; High confidence in function and specificity YP_691997.1 (heat shock protein 15, Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog)) identified by match to PFAM protein family HMMPF01479 InterPro: S4 domain; High confidence in function and specificity YP_691998.1 identified by match to PFAM protein family HMMPF00702 InterPro: Haloacid dehalogenase/epoxide hydrolase family; Family membership YP_691999.1 ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose YP_692000.1 (inositol monophosphatase family protein) identified by sequencesimilarity; InterPro: Inositol monophosphatase; High confidence in function and specificity YP_692002.1 monooxygenase flavin-binding family identified by sequence similarity; InterPro: Flavin-containing monooxygenase (FMO); Family membership YP_692005.1 transcriptional regulator TetR family identified by sequencesimilarity; InterPro: Bacterial regulatory proteins TetR family; Family membership YP_692006.1 oxidoreductase (short chaindehydrogenase/reductase family) identified by match to TIGR protein family HMMTIGR01500 InterPro: Short-chain dehydrogenase/reductase (SDR) superfamily; Family membership YP_692008.1 monooxygenase flavin-binding family identified by sequence similarity; InterPro: Flavin-containing monooxygenase (FMO); Function unclear YP_692011.1 ABC transporter ATP-binding protein identified by sequencesimilarity; InterPro: AAA ATPase superfamily belongs to the abc transporter family. ef3 subfamily; Specificity unclear YP_692013.1 (conserved hypothetical protein ) YP_692014.1 protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic YP_692016.1 catalyzes the formation of 2-oxoglutarate from isocitrate YP_692017.1 (ABC transporter ATP-binding protein, ) identified by match to PFAM protein family HMMPF00005 InterPro: AAA ATPase superfamily; Family membership YP_692018.1 (ATP-binding cassette (ABC) transporters, permease protein, ) identified by match to PFAM protein family HMMPF04306 InterPro: ABC 2 transport system integral membrane protein; High confidence in function and specificity YP_692019.1 predicted membrane protein YP_692022.1 identified by sequencesimilarity; InterPro: Pyridoxamine 5-phosphate oxidase; High confidence in function and specificity YP_692025.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation YP_692026.1 Na+-dependent transporters of the SNF family similar pst:PSPTO4514; Family membership YP_692028.1 identified by sequencesimilarity; Specificity unclear YP_692029.1 identified by sequence similarity; Family membership YP_692030.1 identified by match to TIGR protein family HMMTIGR00634 InterPro: DNA repair protein RecN; High confidence in function and specificity YP_692032.1 Heat-inducible transcription repressor hrcA homolog InterPro: Negative regulator of class I heat shock protein; High confidence in function and specificity YP_692033.1 identified by match to PFAM protein family HMMPF01025 InterPro: GrpE protein; High confidence in function and specificity YP_692034.1 (dnaK protein), (Chaperone protein dnaK), (Heat shock protein 70) identified by sequencesimilarity; InterPro: Heat shock protein hsp70; High confidence in function and specificity YP_692035.1 (dnaJ protein), (Chaperone protein dnaJ), identified by sequencesimilarity; InterPro: DnaJ C terminal domain; High confidence in function and specificity YP_692036.1 identified by sequence similarity; identified by match to TIGRFAM protein family HMMTIGR00036 InterPro: Dihydrodipicolinate reductase; High confidence in function and specificity YP_692037.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers YP_692038.1 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity YP_692039.1 identified by sequencesimilarity; Specificity unclear YP_692040.1 conserved hypothetical protein TIGR00253 identified by sequence similarity; InterPro: Uncharacterized protein family UPF0044 YP_692041.1 identified by sequencesimilarity; InterPro: FtsJ cell division protein; Specificity unclear YP_692042.1 identified by sequence similarity; InterPro: Peptidase family M41; Specificity unclear YP_692043.1 identified by sequence similarity; InterPro: Dihydropteroate synthase; High confidence in function and specificity YP_692044.1 identified by sequence similarity; InterPro: Phosphoglucomutase and phosphomannomutase family; High confidence in function and specificity YP_692045.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate YP_692046.1 Family membership YP_692048.1 identified by sequence similarity. InterPro: S1 RNA binding domain; High confidence in function and specificity YP_692049.1 identified by sequence similarity; High confidence in function and specificity YP_692050.1 identified by sequencesimilarity; InterPro: Ribosome-binding factor A; High confidence in function and specificity YP_692051.1 ABC efflux transporter permease/ATP-bindingprotein identified by sequence similarity; InterPro: tRNA pseudouridine synthase B; High confidence in function and specificity YP_692052.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence YP_692053.1 identified by sequence similarity; InterPro: 3 exoribonuclease family; High confidence in function and specificity YP_692054.1 identified by sequence similarity; InterPro: AMP-dependent synthetase and ligase; High confidence in function and specificity YP_692055.1 Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5) YP_692056.1 (pantoate--beta-alanine ligase) identified by sequencesimilarity; InterPro: Pantoate-beta-alanine ligase; High confidence in function and specificity YP_692057.1 identified by sequence similarity; InterPro: Ketopantoate hydroxymethyltransferase; High confidence in function and specificity YP_692058.1 identified by sequence similarity; InterPro: Deoxynucleoside kinase; Family membership YP_692059.1 (2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase) identified by sequencesimilarity; InterPro: 78-Dihydro-6-hydroxymethylpterin-pyrophosphokinase; High confidence in function and specificity YP_692060.1 identified by sequence similarity; InterPro: Poly A polymerase family; High confidence in function and specificity YP_692061.1 ) identified by match to PFAM protein family HMMPF00072 InterPro: Sigma-54 factor interaction domain; High confidence in function and specificity YP_692062.1 (sensory box histidine kinase ) identified by match to PFAM protein family HMMPF02518; InterPro: Sodium:solute symporter family; Family membership YP_692063.1 identified by Glimmer2 YP_692064.1 Glutamyl-tRNA synthetase (EC 6.1.1.17) (Glutamate--tRNA ligase) (GluRS)., Glutamyl-tRNA synthetase, class Ic, tRNA synthetases class I (E and Q), catalytic domain, gltX_bact: glutamyl-tRNA synthetase; High confidence in function and specificity YP_692065.1 (C4-type zinc finger protein DksA/TraR family) identified by match to PFAM protein family HMMPF01258; High confidence in function and specificity YP_692066.1 (aminotransferase, ) identified by match to PFAM protein family HMMPF00155, Family membership YP_692067.1 (sugar fermentation stimulation protein); High confidence in function and specificity YP_692068.1 catalyzes the phosphorylation of protein substrates at serine and threonine residues in vitro; specific substrate in vivo has not been identified yet; plays a role in long-term cell survival and expression of surface appendages YP_692069.1 (Rieske 2Fe-2S family protein) identified by match to PFAM protein family HMMPF00355 InterPro: Rieske iron-sulfur protein 2Fe-2S subunit; Function unclear YP_692070.1 (carbohydrate kinase, PfkB family) identified by sequencesimilarity; High confidence in function and specificity YP_692071.1 unknown EC_number 2.4.2.129; (penicillin-binding protein 1B (PBP-1b) (PBP1b) (Murein polymerase)[Includes: Penicillin-insensitive transglycosylase (EC 2.4.1.129)(Peptidoglycan glycosyltransferase) (Peptidoglycan TGase); Penicillin-sensitive transpeptidase (EC 3.4.-.-) (DD-transpeptidase)]) identified by sequencesimilarity; InterPro: Penicillin binding protein transpeptidase domain; Function unclear YP_692073.1 conserved hypothetical protein TIGR00011 identified by sequence similarity; Function unclear YP_692074.1 (glutamate-1-semialdehyde-21-aminomutase) identified by sequencesimilarity; InterPro: Glutamate-1-semialdehyde-21-aminomutase; High confidence in function and specificity YP_692075.1 (thiamine-phosphate pyrophosphorylase) identified by sequencesimilarity; InterPro: Thiamine monophosphate synthase (TMP); High confidence in function and specificity YP_692076.1 (phosphomethylpyrimidine kinase) identified by sequencesimilarity; High confidence in function and specificity YP_692078.1 identified by match to PFAM protein family HMMPF00654 InterPro: Voltage gated chloride channels; Specificity unclear YP_692079.1 identified by sequencesimilarity; InterPro: N-acetyl-gamma-glutamyl-phosphate reductase active site; High confidence in function and specificity YP_692081.1 conserved hypothetical protein identified by sequencesimilarity; Function unclear YP_692082.1 HesB/YadR/YfhF family protein identified by sequencesimilarity; InterPro: Hypothetical hesB/yadR/yfhF family; Family membership YP_692084.1 catalyzes hydrolysis of 1,6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate; involved in murein recycling YP_692085.1 peptidase M23/M37 family identified by match to PFAM protein family HMMPF04225; Family membership YP_692086.1 (tyrosyl-tRNA synthetase) identified by sequence similarity; InterPro: Tyrosyl-tRNA synthetase; High confidence in function and specificity YP_692087.1 (long-chain fatty-acid-CoA ligase ) identified by match to TIGR protein family HMMTIGR01734 InterPro: AMP-dependent synthetase and ligase; High confidence in function and specificity YP_692088.1 (birA bifunctional protein) identified by sequence similarity; InterPro: Biotin--acetyl-CoA-carboxylase ligase; Specificity unclear YP_692089.1 transcriptional activator identified by match to PFAM protein family HMMPF03309; Family membership YP_692091.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu YP_692092.1 identified by sequence similarity; InterPro: Protein secE/sec61-gamma protein; Family membership YP_692093.1 identified by match to PFAM protein family HMMPF02357; High confidence in function and specificity YP_692094.1 binds directly to 23S ribosomal RNA YP_692095.1 (ribosomal protein L1) identified by sequence similarity; InterPro: Ribosomal protein L1; High confidence in function and specificity YP_692096.1 (ribosomal protein L10) identified by sequencesimilarity; InterPro: Ribosomal protein L10; High confidence in function and specificity YP_692097.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors YP_692098.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme YP_692099.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter YP_692100.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance YP_692101.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit YP_692102.1 (fus), (far) (translation elongation factor G), (elongation factor G) identified by sequencesimilarity; InterPro: Translation elongation factor G; High confidence in function and specificity YP_692103.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu YP_692104.1 identified by sequence similarity; InterPro: UDP-glucose/GDP-mannose dehydrogenase family; High confidence in function and specificity YP_692105.1 Function unclear YP_692106.1 Function unclear YP_692107.1 (alginate biosynthesis regulator AlgK) identified by sequence similarity; InterPro: TPR repeat; High confidence in function and specificity YP_692108.1 (outer membrane protein AlgE); High confidence in function and specificity YP_692109.1 High confidence in function and specificity YP_692110.1 High confidence in function and specificity YP_692111.1 High confidence in function and specificity YP_692112.1 identified by sequencesimilarity; Function unclear YP_692113.1 Depolymerizes alginate by cleaving the beta-1,4 glycosidic bond: may enhance the production of alginate by controlling the length of the polymer chain during export YP_692114.1 alginate-C5-mannuronan-epimerase AlgG, ); identified by sequence similarity; Family membership YP_692115.1 (mannose-1-phosphateguanylyltransferase/mannose-6-p hosphate isomerase) identified by match to PFAM protein family HMMPF00483 InterPro: ADP-glucose pyrophosphorylase; High confidence in function and specificity YP_692116.1 (ribosomal protein S10) identified by sequence similarity; InterPro: Ribosomal protein S10; High confidence in function and specificity YP_692117.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin YP_692118.1 (ribosomal protein L4) identified by sequence similarity; InterPro: Ribosomal protein L4/L1e; High confidence in function and specificity YP_692119.1 (ribosomal protein L23) identified by sequencesimilarity; InterPro: Ribosomal L23 protein; High confidence in function and specificity YP_692120.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation YP_692121.1 (ribosomal protein S19) identified by sequencesimilarity; InterPro: Ribosomal protein S19; High confidence in function and specificity YP_692122.1 (ribosomal protein L22) identified by match to PFAM protein family HMMPF00237; High confidence in function and specificity YP_692123.1 (ribosomal protein S3) identified by sequencesimilarity; InterPro: Ribosomal protein S3; High confidence in function and specificity YP_692124.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e YP_692125.1 identified by sequence similarity; InterPro: Ribosomal protein L29; High confidence in function and specificity YP_692126.1 (ribosomal protein S17) identified by sequencesimilarity; InterPro: Ribosomal protein S17; High confidence in function and specificity YP_692127.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase YP_692128.1 (ribosomal protein L24) identified by sequencesimilarity; InterPro: Ribosomal protein L24; High confidence in function and specificity YP_692129.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13 YP_692130.1 (ribosomal protein S14) identified by sequencesimilarity; InterPro: Ribosomal protein S14; High confidence in function and specificity YP_692131.1 (ribosomal protein S8) identified by sequencesimilarity; InterPro: Ribosomal protein S8; High confidence in function and specificity YP_692132.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance YP_692133.1 (ribosomal protein L18) identified by sequence similarity; InterPro: Ribosomal protein L18P/L5E; High confidence in function and specificity YP_692134.1 (ribosomal protein S5) identified by sequencesimilarity; InterPro: Ribosomal protein S5; High confidence in function and specificity YP_692135.1 identified by sequencesimilarity; InterPro: Ribosomal protein L30; High confidence in function and specificity YP_692136.1 (ribosomal protein L15) identified by sequence similarity; InterPro: Ribosomal protein L15; High confidence in function and specificity YP_692137.1 (Sec-dependent secretion protein SecY) identified by sequence similarity; InterPro: SecY protein; High confidence in function and specificity YP_692138.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif YP_692139.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA YP_692140.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3 YP_692141.1 (ribosomal protein S4) identified by sequence similarity; InterPro: Ribosomal protein S4; High confidence in function and specificity YP_692142.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme YP_692143.1 identified by match to PFAM protein family HMMPF01196 InterPro: Ribosomal protein L17; High confidence in function and specificity YP_692146.1 Function unclear YP_692147.1 identified by sequence similarity; High confidence in function and specificity YP_692148.1 DNA-binding response regulator LuxR family identified by match to PFAM protein family HMMPF00072 InterPro: Bacterial regulatory protein LuxR family; Family membership YP_692149.1 major facilitator family transporter identified by match to PFAM protein family HMMPF03605 InterPro: General substrate transporters; Family membership YP_692150.1 identified by sequencesimilarity; InterPro: Single-strand binding protein family; High confidence in function and specificity YP_692153.1 (xcpQ) (type II secretion pathway protein XcpQ) identified by sequence similarity; InterPro: General (type II) secretion pathway (GSP) D protein; Function unclear YP_692155.1 adenylate cyclase family protein identified by Glimmer2; InterPro: Guanylate cyclase; Specificity unclear YP_692156.1 hydrolase alpha/beta fold family identified by match to TIGR protein family HMMTIGR01738 InterPro: Alpha/beta hydrolase fold; Family membership YP_692158.1 nitrobenzoate reductase identified by sequencesimilarity; InterPro: Nitroreductase family; High confidence in function and specificity YP_692160.1 ATPase AAA family identified by match to PFAM protein family HMMPF00004 InterPro: AAA-protein (ATPases associated with various cellular activities); Specificity unclear YP_692162.1 sensor histidine kinase identified by match to PFAM protein family HMMPF02518 InterPro: Histidine kinase C-terminal; Function unclear YP_692163.1 Hypothetical protein YP_692165.1 Hypothetical protein YP_692166.1 transcriptional regulator AraC family identified by match to PFAM protein family HMMPF00165 InterPro: AraC type helix-turn-helix; Family membership YP_692167.1 identified by sequencesimilarity YP_692171.1 transferases identified by sequence similarity; InterPro: Polyprenyl synthetase; Function unclear YP_692172.1 (ribosomal protein L21) identified by sequence similarity; InterPro: Ribosomal protein L21; High confidence in function and specificity YP_692173.1 involved in the peptidyltransferase reaction during translation YP_692174.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication YP_692175.1 catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis YP_692176.1 (ribosomal protein S20) identified by sequencesimilarity; InterPro: Ribosomal protein S20; High confidence in function and specificity YP_692177.1 identified by match to PFAM protein family HMMPF03023 InterPro: Virulence factor MVIN-like; Family membership YP_692178.1 (riboflavin biosynthesis protein RibF) identified by sequence similarity; InterPro: Riboflavin kinase / FAD synthetase; High confidence in function and specificity YP_692179.1 identified by sequencesimilarity; InterPro: Isoleucyl-tRNA synthetase; High confidence in function and specificity YP_692180.1 Region start changed from 501650 to 501683 (-33 bases) YP_692181.1 peptidyl-prolyl cis-trans isomerase FKBP-type identified by sequencesimilarity; InterPro: FKBP-type peptidyl-prolyl cis-trans isomerase (PPIase); Specificity unclear YP_692182.1 identified by match to TIGR protein family HMMTIGR00216 InterPro: LytB protein; High confidence in function and specificity YP_692183.1 ( pilus biogenesis protein); Family membership YP_692187.1 Conserved hypothetical protein YP_692188.1 secretion protein identifiedby sequence similarity; InterPro: Fimbrial protein pilin; High confidence in function and specificity YP_692190.1 oxidoreductase FAD-binding identified by sequencesimilarity; InterPro: D-amino acid oxidase; Function unclear YP_692192.1 identified by match to PFAM protein family HMMPF04306 InterPro: Histidine kinase C-terminal; High confidence in function and specificity YP_692194.1 NAD+ synthase (glutamine-hydrolysing) identified by sequencesimilarity; Specificity unclear YP_692195.1 identified by sequence similarity; shows high similarity to the PFAM(UPF0169)protein. Members of this family are predicted to be lipoproteins. The function of these proteins is unknown. Possibly this protein is involved in DNA uptake.; Function unclear YP_692196.1 ThrB family protein/aminotransferase class III) identified by sequencesimilarity; InterPro: Pseudouridine synthase Rlu family; High confidence in function and specificity YP_692199.1 Specificity unclear YP_692201.1 catalyzes the formation of 2-acetolactate from pyruvate, leucine sensitive; also known as acetolactate synthase large subunit YP_692202.1 with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit YP_692204.1 participates in controlling several genes involved in isoleucine and valine biosynthesis; activates the transcription of the ilvC gene in the presence of acetolactate or acetohydroxybutyrate YP_692205.1 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis YP_692206.1 identified by match to PFAM protein family HMMPF03653; High confidence in function and specificity YP_692208.1 cytosolic protein with phosphatidylglycerol kinase activity; undetermined physiological role YP_692210.1 transcriptional regulator TetR family identified by match to PFAM protein family HMMPF00440 InterPro: Bacterial regulatory proteins TetR family; Family membership YP_692212.1 identified by match to PFAM protein family HMMPF00133 InterPro: Valyl-tRNA synthetase; High confidence in function and specificity YP_692214.1 identified by sequencesimilarity; High confidence in function and specificity YP_692215.1 (leucyl aminopeptidase, leucine aminopeptidase, cytosol aminopeptidase) identified by sequence similarity; identified by match to PFAM protein family HMMPF00883 InterPro: Cytosol aminopeptidase; High confidence in function and specificity YP_692216.1 (conserved hypothetical protein) identified by sequencesimilarity; Specificity unclear YP_692217.1 (conserved hypothetical protein) identified by sequence similarity; Specificity unclear YP_692220.1 isomerase identified by sequence similarity; InterPro: Queuosine biosynthesis protein; High confidence in function and specificity YP_692221.1 identified by sequence similarity; InterPro: Queuine and other tRNA-ribosyltransferase Queuine tRNA-ribosyltransferase; High confidence in function and specificity YP_692222.1 identified by match to PFAM protein family HMMPF02699 InterPro: Domain of unknown function DUF219; Family membership YP_692223.1 (protein-export membrane protein SecD) identified by sequencesimilarity; High confidence in function and specificity YP_692224.1 (protein-export membrane protein SecF) identified by match to PFAM protein family HMMPF03631 InterPro: SecD/SecF/SecDF export membrane proteins; High confidence in function and specificity YP_692226.1 (aminotransferase, ) identified by sequence similarity; identified by match to PFAM protein family HMMPF00155 InterPro: Aminotransferases class-I; Family membership YP_692227.1 carbon-nitrogen ligase with glutamine as amido-N-donor, amidase family protein identified by sequencesimilarity; InterPro: Amidase; Family membership YP_692228.1 (D-isomer specific 2-hydroxyacid dehydrogenase family protein) identified by match to PFAM protein family HMMPF00389; InterPro: D-isomer specific 2-hydroxyacid dehydrogenase; Family membership YP_692229.1 (aminotransferase, ) identified by sequence similarity; identified by match to PFAM protein family HMMPF00202 InterPro: Aminotransferase class-III pyridoxal-phosphate; Specificity unclear YP_692230.1 identified by sequence similarity; identified by match to PFAM protein family HMMPF00180 InterPro: Isocitrate and isopropylmalate dehydrogenases; High confidence in function and specificity YP_692231.1 (succinate-semialdehyde dehydrogenase) identified by sequencesimilarity; InterPro: Aldehyde dehydrogenase family; High confidence in function and specificity YP_692232.1 (myo-inositol-1(or 4)-monophosphatase (extragenic suppressor protein SuhB)) identified by sequence similarity; InterPro: Inositol monophosphatase; High confidence in function and specificity YP_692233.1 RNA methyltransferase TrmH family group 1 identified by match to PFAM protein family HMMPF00588 InterPro: RNA methyltransferase TrmH family group 1; Family membership YP_692234.1 identified by sequence similarity; InterPro: Bacterial transferase hexapeptide repeat; High confidence in function and specificity YP_692235.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1 YP_692236.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation YP_692237.1 the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response YP_692238.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP YP_692239.1 identified by match to PFAM protein family HMMPF00288 InterPro: 4-diphosphocytidyl-2C-methyl-D-erythritol kinase; High confidence in function and specificity YP_692240.1 outer membrane lipoprotein LolB identified by match to PFAM protein family HMMPF03550; Family membership YP_692241.1 identified by match to PFAM protein family HMMPF00515; Specificity unclear YP_692242.1 glutamyl-tRNA reductase identifiedby sequence similarity; InterPro: Glutamyl-tRNA reductase; High confidence in function and specificity YP_692243.1 identified by sequence similarity; InterPro: Peptide chain release factor 1; High confidence in function and specificity YP_692244.1 (methyl transferase) identified by sequencesimilarity; InterPro: Modification methylase HemK family; Function unclear YP_692245.1 molybdopterin biosynthesis MoeB protein identified by sequencesimilarity; InterPro: UBA/THIF-type NAD/FAD binding fold; Family membership YP_692246.1 identified by sequence similarity; InterPro: Enoyl-CoA hydratase/isomerase; Specificity unclear YP_692247.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA YP_692248.1 identified by sequence similarity; InterPro: Glutamyl-tRNA(Gln) amidotransferase A subunit; High confidence in function and specificity YP_692249.1 identified by sequence similarity; High confidence in function and specificity YP_692250.1 functions in MreBCD complex in some organisms YP_692251.1 identified by sequencesimilarity; High confidence in function and specificity YP_692252.1 identified by match to PFAM protein family HMMPF04093; High confidence in function and specificity YP_692253.1 identified by match to TIGR protein family HMMTIGR00172 InterPro: Maf-like protein; High confidence in function and specificity YP_692255.1 identified by sequencesimilarity; InterPro: Carbon-nitrogen hydrolase; Family membership YP_692256.1 identified by sequence similarity; InterPro: modulator of DNA gyrase; High confidence in function and specificity YP_692257.1 InterPro: Cyclic nucleotide-binding domain; Function unclear YP_692258.1 (MORN domain protein) identified by match to PFAM protein family HMMPF02493 InterPro: MORN motif The MORN (Membrane Occupation and Recognition Nexus) motif is found in multiple copies in several proteins including junctophilins. The function of this motif is unknown.; Conserved hypothetical protein YP_692259.1 identified by sequencesimilarity YP_692260.1 identified by sequence similarity; InterPro: modulator of DNA gyrase; Function unclear YP_692261.1 identified by match to TIGR protein family HMMTIGR00400 InterPro: Divalent cation transporter; High confidence in function and specificity YP_692262.1 PpiC-type peptidyl-prolyl cis-trans isomerase; Function unclear YP_692263.1 narI. Respiratory nitrate reductase 1 gamma chain InterPro: Nitrate reductase gamma subunit; High confidence in function and specificity YP_692264.1 narJ. Respiratory nitrate reductase 1 delta chain InterPro: Nitrate reductase delta subunit; High confidence in function and specificity YP_692265.1 narH. Respiratory nitrate reductase 1 beta chain; High confidence in function and specificity YP_692266.1 (Respiratory nitrate reductase 1 alpha chain) identified by sequencesimilarity; High confidence in function and specificity YP_692267.1 identified by sequence similarity; Family membership YP_692268.1 Phosphotransferase system HPr-related protein NPr identified by sequencesimilarity; InterPro: Phosphocarrier HPr protein; Family membership YP_692269.1 identified by sequencesimilarity YP_692270.1 identified by sequencesimilarity; InterPro: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; Family membership YP_692271.1 sigma54 modulation protein) identified by sequence similarity; InterPro: Sigma 54 modulation protein / S30EA ribosomal protein; Family membership YP_692272.1 identified by sequencesimilarity; InterPro: Sigma-54 factor family; High confidence in function and specificity YP_692273.1 identified by match to TIGR protein family HMMTIGR00968 InterPro: AAA ATPase superfamily; Specificity unclear YP_692274.1 identified by match to PFAM protein family HMMPF03968 YP_692276.1 identified by match to TIGR protein family HMMTIGR01662; Specificity unclear YP_692277.1 KpsF/GutQ family protein identified by match to PFAM protein family HMMPF01380 InterPro: KpsF/GutQ family protein; Family membership YP_692278.1 (ttg2D) identified by sequence similarity; This family is a transporter which shows similarity to ABC transporters; Family membership YP_692279.1 identified by sequence similarity; Family membership YP_692280.1 (UDP-N-acetylglucosamine1-carboxyvinyltransferase) Alternate gene symbol: ttg2G; identified by sequence similarity; High confidence in function and specificity YP_692281.1 short form of enzyme; requires HisZ for function; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms heteromultimer of HisG and HisZ YP_692282.1 Region start changed from 619317 to 619215 (102 bases) YP_692283.1 catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis YP_692285.1 (algW) (HtrA-like protease AlgW) identified by match to PFAM protein family HMMPF00595; Function unclear YP_692286.1 (conserved hypothetical protein TIGR00486) YP_692287.1 (conserved hypothetical protein TIGR00147) identified by sequencesimilarity; InterPro: DAG-kinase catalytic domain (presumed) YP_692288.1 identified by sequencesimilarity YP_692289.1 identified by sequencesimilarity; InterPro: Esterase/lipase/thioesterase family active site; Specificity unclear YP_692290.1 (AFG1-like ATPase, )identify by similarity to Pfam protein family PF03969 (AFG1_ATPase).; Family membership YP_692291.1 acyl-CoA dehydrogenase identified by sequencesimilarity; InterPro: Acyl-CoA dehydrogenase; Specificity unclear YP_692292.1 identified by sequencesimilarity; Family membership YP_692295.1 oxidoreductase aldo/keto reductase family identified by match to TIGR protein family HMMTIGR01293 InterPro: Aldo/keto reductase family; Family membership YP_692296.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit YP_692297.1 identified by sequence similarity; InterPro: Ribosomal protein S9; High confidence in function and specificity YP_692298.1 (ubiquinol--cytochrome c reductase iron-sulfursubunit) identified by match to PFAM protein family HMMPF00355 InterPro: Rieske iron-sulfur protein 2Fe-2S subunit; High confidence in function and specificity YP_692299.1 (ubiquinol--cytochrome c reductase cytochrome b) identified by sequence similarity; InterPro: Cytochrome b/b6; High confidence in function and specificity YP_692300.1 (ubiquinol--cytochrome c reductase cytochrome c1) identified by sequencesimilarity; InterPro: Cytochrome c1; High confidence in function and specificity YP_692301.1 identified by sequencesimilarity; InterPro: Glutathione S-transferase C terminus; High confidence in function and specificity YP_692302.1 identified by sequence similarity; High confidence in function and specificity YP_692303.1 Protein which is posttranslationally modified by the attachment of at least one lipid or fatty acid, e.g. farnesyl, palmitate and myristate.; Function unclear YP_692304.1 catalyzes the isomerization of sedoheptulose 7-phosphate to D-glycero-D-manno-heptose 7-phosphate YP_692305.1 InterPro: Uncharacterised protein family UPF0102 YP_692306.1 Protein which is posttranslationally modified by the attachment of at least one lipid or fatty acid, e.g. farnesyl, palmitate and myristate; Function unclear YP_692307.1 (tetrapyrrole methylase family protein) identified by match to PFAM protein family HMMPF00590 InterPro: Uncharacterized protein family UPF0011 Methylase function: Catalysis of the transfer of a methyl group to an acceptor molecule; Family membership YP_692308.1 InterPro: Metallo-beta-lactamase superfamily YP_692309.1 (conserved hypothetical protein TIGR00242) identified by match to PFAM protein family HMMPF02381 InterPro: Domain of unknown function UPF0040 YP_692310.1 InterPro: Methyltransferase family; Specificity unclear YP_692311.1 identified by sequence similarity; Family membership YP_692312.1 identified by sequence similarity; InterPro: Penicillin binding protein transpeptidase domain; Hypothetical protein YP_692313.1 (UDP-N-acetylmuramoylalanyl-D-glutamate-2 6-diaminopimelate ligase) identified by match to PFAM protein family HMMPF01225 InterPro: Cytoplasmic peptidoglycan synthetases N-terminal; High confidence in function and specificity YP_692314.1 (UDP-N-acetylmuramoylalanyl-D-glutamyl-2 6-diaminopimelate--D-alanyl-D-alanyl ligase) identified by sequence similarity; InterPro: Cytoplasmic peptidoglycan synthetases N-terminal; High confidence in function and specificity YP_692315.1 identified by match to PFAM protein family HMMPF04306 InterPro: Phospho-N-acetylmuramoyl-pentapeptide-transferase; High confidence in function and specificity YP_692316.1 identified by match to PFAM protein family HMMPF01225 InterPro: Cytoplasmic peptidoglycan synthetases N-terminal; High confidence in function and specificity YP_692317.1 identified by match to PFAM protein family HMMPF01098 InterPro: Cell cycle proteins; Family membership YP_692318.1 (UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapep tide) pyrophosphoryl-undecaprenolN-acetylglucosamine transferase) identified by match to PFAM protein family HMMPF04101 InterPro: Glycosyltransferase family 28; High confidence in function and specificity YP_692319.1 (UDP-N-acetylmuramate--alanine ligase) identified by match to PFAM protein family HMMPF01225; High confidence in function and specificity YP_692320.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli YP_692321.1 identified by match to PFAM protein family HMMPF03799; High confidence in function and specificity YP_692322.1 identified by sequencesimilarity; InterPro: Cell division protein FtsA; High confidence in function and specificity YP_692323.1 identified by sequencesimilarity; InterPro: Cell division protein FtsZ; High confidence in function and specificity YP_692324.1 zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis YP_692326.1 identified by sequencesimilarity; InterPro: Peptidase family M23/M37; Family membership YP_692327.1 identified by sequence similarity; InterPro: SecA protein; High confidence in function and specificity YP_692328.1 bifunctional arginine biosynthesis protein ArgJ; functions at the 1st and 5th steps in arginine biosynthesis; involved in synthesis of acetylglutamate from glutamate and acetyl-CoA and ornithine by transacetylation between acetylornithine and glutmate YP_692329.1 identified by sequencesimilarity; InterPro: Mutator MutT involved in the go system responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine) from dna and the nucleotide pool. 8-oxo-dgtp is inserted opposite da and dc residues of template dna with almost equal efficiency thus leading to a.t to g.c transversions. mutt specifically degrades 8-oxo-dgtp to the monophosphate belongs to the nudix hydrolase family; High confidence in function and specificity YP_692330.1 identified by sequence similarity YP_692331.1 (kinase ) identified by sequencesimilarity; High confidence in function and specificity YP_692332.1 identified by sequence similarity InterPro: Prepilin cysteine protease (C20) type IV; High confidence in function and specificity YP_692333.1 identified by sequence similarity; Family membership YP_692334.1 identified by sequence similarity and match to PFAM protein family HMMPF00437 InterPro: Bacterial type II secretion system protein E; Family membership YP_692335.1 (Pilin protein family, ); identify by similarity to PFAM protein family PF00114; Family membership YP_692337.1 (nicotinate-nucleotide pyrophosphorylase) identified by sequencesimilarity; InterPro: Nicotinate-nucleotide pyrophosphorylase; High confidence in function and specificity YP_692338.1 (sodium/alanine symporter, amino acid carrier protein alst, Na(+)-linked D-alanine/glycine permease, sodium/proton-dependent alanine carrier protein) identified by sequence similarity; identified by match to PFAM protein family HMMPF01235 and TIGRFAM protein family HMMTIGR00835; InterPro: Sodium:alanine symporter family; High confidence in function and specificity YP_692339.1 identified by Glimmer2; high similarity to hypothetical protein pa4523 of Pseudomonas aeruginosa. YP_692340.1 identified by sequencesimilarity; High confidence in function and specificity YP_692341.1 Family membership YP_692342.1 E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC YP_692343.1 (pyruvate dehydrogenase dihydrolipoamideacetyltransferase component) identified by sequencesimilarity; InterPro: 2-Oxo acid dehydrogenase acyltransferase catalytic domain; High confidence in function and specificity YP_692345.1 Possible response regulators consisting of a CheY-like receiver domain and a HTH DNA-binding domain. Identified by match to TIGR protein family HMMTIGR01387 InterPro: Response regulator receiver domain; Family membership YP_692346.1 Phosphotransferase with a nitrogenous group as acceptor; Family membership YP_692347.1 identified by match to TIGR protein family HMMTIGR00636 InterPro: Protein of unknown function DUF80 YP_692348.1 InterPro: TonB-dependent receptor protein; Family membership YP_692349.1 2-dehydropantoate 2-reductase identified by sequence similarity; InterPro: Ketopantoate reductase ApbA/PanE; Specificity unclear YP_692350.1 (muropeptide permease ampG, ) identified by sequence similarity; identified by match to TIGRFAM protein family HMMTIGR00901; Function unclear YP_692351.1 identified by match to TIGR protein family HMMTIGR00589 InterPro: Methylated-DNA--protein-cysteine methyltransferase YP_692352.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis YP_692353.1 identified by sequence similarity; InterPro: Chaperonins cpn10 (10 Kd subunit); High confidence in function and specificity YP_692354.1 identified by sequence similarity; InterPro: TCP-1 (Tailless complex polypeptide)/cpn60 chaperonin family; High confidence in function and specificity YP_692355.1 (reverse transcriptase homolog, group II intron-encoding maturase) identified by sequencesimilarity; InterPro: RNA-directed DNA polymerase (Reverse transcriptase); Family membership YP_692356.1 identified by sequencesimilarity; InterPro: Rhomboid family shows homololgy to a Rhomboid-like protein. This family contains integral membrane proteins that arerelated to Drosophila rhomboid protein P20350. Members of this family are found in bacteria and eukaryotes. These proteins contain three strongly conserved histidines in the transmembrane regions that may be involved in the as yet unknown function of these proteins. YP_692357.1 hypothetical protein, TMHMM: reporting 6 transmembrane helices YP_692358.1 catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis YP_692360.1 ribosomal-protein-alanine N-acetyltransferase (GNAT family) identified by match to PFAM protein family HMMPF00583 InterPro: GCN5-related N-acetyltransferase; Specificity unclear YP_692363.1 identified by sequencesimilarity; InterPro: Peptide chain release factor 3; Hypothetical protein YP_692366.1 Hypothetical protein YP_692367.1 identified by match to PFAM protein family HMMPF02801 InterPro: Beta-ketoacyl synthase; Family membership YP_692368.1 (3-ketoacyl-CoA thiolase) identified by sequencesimilarity; InterPro: Thiolase; Specificity unclear YP_692369.1 SodB, superoxide dismutase identified by sequence similarity; Specificity unclear YP_692375.1 identified by match to PFAM protein family HMMPF03781 YP_692376.1 3-hydroxyacyl-CoA dehydrogenase identified by sequencesimilarity; InterPro: Short-chain dehydrogenase/reductase (SDR) superfamily; High confidence in function and specificity YP_692377.1 (decarboxylase family protein) identified by sequencesimilarity; Family membership YP_692379.1 (DNA-damage-inducible protein P) identified by sequence similarity; InterPro: UMUC family (DNA-repair); High confidence in function and specificity YP_692380.1 oxidoreductase (acting on paired donors with incorporation of molecular oxygen with NADH or NADPH as one donor, and incorporation of one atom of oxygen) identified by sequence similarity; InterPro: Aromatic-ring hydroxylase (flavoprotein monooxygenase); Function unclear YP_692381.1 rRNA large subunit methyltransferase A identified by match to PFAM protein family HMMPF01209 InterPro: SAM (and some other nucleotide) binding motif; High confidence in function and specificity YP_692383.1 oxidoreductase (acting on the CH-OH group of donors with NAD+ or NADP+ as acceptor) identified by sequencesimilarity; InterPro: Short-chain dehydrogenase/reductase (SDR) superfamily; Family membership YP_692385.1 (transcriptional regulator AraC family) identified by match to PFAM protein family HMMPF00165 InterPro: AraC type helix-turn-helix; High confidence in function and specificity YP_692386.1 identified by sequence similarity; InterPro: HMGCR/Patched 5TM box; Function unclear YP_692387.1 (BNR domain protein) identified by match to PFAM protein family HMMPF02012 InterPro: BNR repeat BNR repaets are short repeats that were found in glycosyl hydrolases as well as other extracellular proteins of unknown function.; Function unclear YP_692388.1 hydrolase (acting on carbon-carbon bonds in ketonic substances) identified by match to TIGR protein family HMMTIGR01738 InterPro: Alpha/beta hydrolase fold; Family membership YP_692390.1 oxidoreductase (acting on iron-sulfur proteins as donors with NAD+ or NADP+ as acceptor) identified by sequence similarity; InterPro: Oxidoreductase FAD and NAD(P)-binding domain; Family membership YP_692391.1 oxidoreductase (acting on paired donors with incorporation of molecular oxygen with NADH or NADPH as one donor, and incorporation of one atom of oxygen) identified by match to PFAM protein family HMMPF00355 InterPro: Rieske iron-sulfur protein 2Fe-2S subunit; Family membership YP_692392.1 oxidoreductase (acting on paired donors with incorporation of molecular oxygen with NADH or NADPH as one donor, and incorporation of one atom of oxygen) identified by match to PFAM protein family HMMPF00355 InterPro: Rieske iron-sulfur protein 2Fe-2S subunit; Family membership YP_692395.1 transcriptional regulator, TetR family; Family membership YP_692396.1 identified by match to PFAM protein family HMMPF00296 InterPro: Bacterial luciferase YP_692397.1 identified by sequencesimilarity; InterPro: Domain of unknown function DUF33; Family membership YP_692398.1 InterPro: Serine proteases trypsin family; Family membership YP_692400.1 catalyzes the formation of oxaloacetate from phosphoenolpyruvate YP_692401.1 Function unclear YP_692402.1 identified by sequencesimilarity YP_692403.1 (plsC) identified by match to TIGR protein family HMMTIGR00530 InterPro: Phospholipid and glycerol acyltransferase (from motifs_6.msf); Family membership YP_692404.1 translation elongation factor P identified by match to TIGR protein family HMMTIGR00038; Family membership YP_692405.1 identified by sequencesimilarity YP_692406.1 identified by sequencesimilarity; InterPro: Rhomboid family YP_692408.1 (TRAP dicarboxylate transporter DctP subunit) identified by sequencesimilarity; Family membership YP_692409.1 (TRAP-type C4-dicarboxylate transport system, small permease component) identified by sequence similarity; TMHMM reporting 4 transmembrane helices; High confidence in function and specificity YP_692410.1 (TRAP dicarboxylate transporter DctM subunit ) identified by sequence similarity; InterPro: DedA family TMHMM reporting 11 transmembrane helices; Family membership YP_692411.1 Function unclear YP_692412.1 (acetyltransferase GNAT family) identified by match to TIGR protein family HMMTIGR01575 InterPro: GCN5-related N-acetyltransferase YP_692414.1 (aconitate hydratase 1) identified by sequencesimilarity; InterPro: Aconitate hydratase N-terminal; High confidence in function and specificity YP_692415.1 Region start changed from 773425 to 773371 (-54 bases) YP_692416.1 (plsC) identified by sequence similarity; InterPro: Phospholipid and glycerol acyltransferase (from motifs_6.msf); High confidence in function and specificity YP_692417.1 glutathione-regulated potassium-protonantiporter identifiedby sequence similarity; InterPro: Na+/H+ exchanger; High confidence in function and specificity YP_692420.1 identified by match to PFAM protein family HMMPF00345; Specificity unclear YP_692421.1 identified by sequence similarity; InterPro: Fimbrial biogenesis outer membrane usher protein; Function unclear YP_692423.1 Oxidoreductase (acting on the aldehyde or oxo group of donors with NAD+ or NADP+ as acceptor) protein identified by match to TIGR protein family HMMTIGR01722 InterPro: Aldehyde dehydrogenase family; Family membership YP_692424.1 catalyzes the condensation of two pyruvates to form acetolactate, implicated in pH homeostasis via the acetoin-2,3-butanediol pathway or in valine biosynthesis YP_692425.1 identified by match to TIGR protein family HMMTIGR01416 YP_692428.1 oxidoreductase (acting on NADH or NADPH with a disulfide as acceptor) identified by sequence similarity; InterPro: Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Family membership YP_692429.1 (conserved hypothetical protein) identified by sequencesimilarity YP_692430.1 Catalyzes the rate-limiting step in dNTP synthesis YP_692431.1 Catalyzes the rate-limiting step in dNTP synthesis YP_692432.1 identified by sequence similarity; InterPro: Response regulator receiver domain; High confidence in function and specificity YP_692433.1 (sensor histidine kinase) identified by match to PFAM protein family HMMPF02518 InterPro: Histidine kinase C-terminal; High confidence in function and specificity YP_692434.1 identified by sequencesimilarity; InterPro: Carbohydrate kinase FGGY family; High confidence in function and specificity YP_692435.1 identified by match to PFAM protein family HMMPF00990; Conserved hypothetical protein YP_692436.1 GGDEF domain protein identified by sequencesimilarity; Conserved hypothetical protein YP_692437.1 identified by sequence similarity and by match to PFAM protein family HMMPF0005; InterPro: AAA ATPase superfamily; Specificity unclear YP_692438.1 catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation YP_692439.1 identified by sequence similarity; InterPro: Aminotransferase class-III pyridoxal-phosphate; High confidence in function and specificity YP_692440.1 (N-methylhydantoinase B, hydantoin utilization protein B, ) identified by sequence similarity; identified by match to PFAM protein family HMMPF02538 InterPro: Hydantoinase B/oxoprolinase; Function unclear YP_692441.1 FecA-like outer membrane receptor identified by sequence similarity; High confidence in function and specificity YP_692442.1 glutaredoxin-related protein; Conserved hypothetical protein YP_692443.1 peroxiredoxin, antioxidant, AhpC/Tsa family, oxidoreductase (acting on NADH or NADPH with a disulfide as acceptor) identified by match to PFAM protein family HMMPF00578 InterPro: Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Family membership YP_692444.1 Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A) YP_692445.1 identified by sequence similarity; identified by match to PFAM protein family HMMPF00764 InterPro: Argininosuccinate synthase; High confidence in function and specificity YP_692446.1 (lactoylglutathione lyase, methylglyoxalase, aldoketomutase, glyoxalase I, ketone-aldehyde mutase, S-D-lactoylglutathione methylglyoxal lyase) identified by sequence similarity; identified by match to PFAM protein family HMMPF00903 InterPro: Glyoxalase I; High confidence in function and specificity YP_692448.1 identified by sequence similarity; InterPro: S6 modification enzyme RimK family protein; High confidence in function and specificity YP_692449.1 (conserved hypothetical protein) identified by sequence similarity YP_692450.1 (sopT; SAT) (Sulfate adenylatetransferase) (ATP-sulfurylase). identified by Glimmer2; InterPro: ATP-sulfurylase Pfam: ATP-sulfurylase; High confidence in function and specificity YP_692452.1 Family membership YP_692453.1 Region start changed from 823759 to 823648 (111 bases) YP_692454.1 identified by match to TIGR protein family HMMTIGR01587 InterPro: DEAD/DEAH box helicase; Hypothetical protein YP_692455.1 identified by sequencesimilarity; InterPro: ATP-dependent DNA helicase RecQ; High confidence in function and specificity YP_692456.1 chromate transporter identified by sequencesimilarity; InterPro: Chromate transporter; High confidence in function and specificity YP_692457.1 ParA family protein identified by sequence similarity; InterPro: ParA family ATPase; Family membership YP_692459.1 High confidence in function and specificity YP_692460.1 Uncharacterized protein, possibly involved in aromatic compounds catabolism YP_692461.1 identified by sequencesimilarity YP_692462.1 identified by match to PFAM protein family HMMPF03561 YP_692463.1 identified by sequence similarity; InterPro: Response regulator receiver domain; Specificity unclear YP_692468.1 InterPro: Bacterial histone-like DNA-binding protein; Family membership YP_692469.1 identified by sequence similarity; InterPro: Aspartyl-tRNA synthetase bacterial type; High confidence in function and specificity YP_692470.1 (conserved hypothetical protein TIGR01033) identified by match to TIGR protein family HMMTIGR01033 InterPro: Domain of unknown function DUF28 YP_692471.1 (crossover junction endodeoxyribonuclease RuvC) identified by match to TIGR protein family HMMTIGR00228 InterPro: Crossover junction endodeoxyribonuclease RuvC; High confidence in function and specificity YP_692472.1 identified by match to PFAM protein family HMMPF02904 InterPro: Bacterial DNA recombination protein RuvA; High confidence in function and specificity YP_692473.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration YP_692474.1 conserved hypothetical protein TIGR00051, has high similarity with predicted thioesterases of COG0824 YP_692475.1 identified by sequence similarity; InterPro: MotA/TolQ/ExbB proton channel family; High confidence in function and specificity YP_692476.1 identified by sequence similarity; InterPro: Biopolymer transport protein ExbD/TolR; High confidence in function and specificity YP_692477.1 conserved hypothetical protein, has certain similarity to proline-rich C-terminus of TolA (PA0971) of Pseudomonas aeruginosa PAO1 YP_692478.1 identified by sequence similarity; High confidence in function and specificity YP_692479.1 (OmpA family protein) identified by match to PFAM protein family HMMPF00691 InterPro: Bacterial outer membrane protein; Family membership YP_692480.1 identified by sequence similarity YP_692481.1 radical activating enzyme identified by sequencesimilarity; InterPro: Radical activating enzymes; Specificity unclear YP_692482.1 (exsB) (exsB protein) identified by sequencesimilarity; InterPro: ExsB protein transcriptional regulatory protein; Function unclear YP_692485.1 identified by match to PFAM protein family HMMPF00376. InterPro: Bacterial regulatory proteins MerR family; Family membership YP_692486.1 Deoxyribodipyrimidine photolyase (DNA photolyase)(Photoreactivating enzyme). (deoxyribodipyrimidine photolyase) identified by sequencesimilarity; InterPro: DNA photolyase; High confidence in function and specificity YP_692487.1 (conserved hypothetical protein) identified by match to PFAM protein family HMMPF01593 Reaction: RCH(2)NH(2) + H(2)O + O(2) = Rcho + NH(3) + H(2)O(2) Cofaktor: FAD; High confidence in function and specificity YP_692489.1 identified by match to PFAM protein family HMMPF02353 InterPro: Cyclopropane-fatty-acyl-phospholipid synthase Reaction: S-adenosyl-L-methionine + phospholipid olefinic fatty acid = S-adenosyl-L-homocysteine + phospholipid cyclopropane fatty acid; High confidence in function and specificity YP_692490.1 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate YP_692491.1 identified by match to PFAM protein family HMMPF01435 InterPro: TPR repeat YP_692493.1 permease PerM identified by sequence similarity; InterPro: Domain of unknown function DUF20; Specificity unclear YP_692494.1 AhpC/TSA family protein identified by match to PFAM protein family HMMPF00578 InterPro: Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Family membership YP_692495.1 identified by sequence similarity; InterPro: ACT domain; Function unclear YP_692496.1 identified by sequence similarity; identified by match to PFAM protein family HMMPF00701 InterPro: Dihydrodipicolinate synthetase; High confidence in function and specificity YP_692497.1 (lipoprotein ) identified by sequencesimilarity YP_692498.1 identified by sequencesimilarity; InterPro: Metallo-beta-lactamase superfamily; Family membership YP_692499.1 (phosphoribosylaminoimidazole-succinocarboxamidesyn thase) identified by sequence similarity; InterPro: SAICAR synthetase; High confidence in function and specificity YP_692502.1 identified by match to PFAM protein family HMMPF00392 InterPro: Bacterial regulatory proteins GntR family; Family membership YP_692504.1 (periplasmic binding domain/transglycosylase SLTdomain fusion protein) identified by sequencesimilarity; InterPro: Bacterial extracellular solute-binding proteins family 3 Bacterial lytic transglycosylases degrade murein via cleavage of the beta-1,4- glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine, with the concomitant formation of a 1,6-anhydrobond in the muramic acid residue. The SLT domain shared by these proteins is involved in catalytic activity. The most conserved part of this domain contains the contains two conserved serines and a glutamate which form part of this active site signature; High confidence in function and specificity YP_692505.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis YP_692507.1 identified by sequencesimilarity YP_692508.1 identified by match to PFAM protein family HMMPF00293; Family membership YP_692509.1 DNA-binding response regulator LuxR family identified by sequence similarity; InterPro: Bacterial regulatory protein LuxR family; Family membership YP_692511.1 identified by match to PFAM protein family HMMPF00293 InterPro: NUDIX hydrolase MuT motif proteins shown to be enzymes have been proposed to degrade compounds that are either deleterious to the cell or are normal metabolites present in excessive concentrations; Family membership YP_692512.1 identified by sequencesimilarity; InterPro: Bacterial transferase hexapeptide repeat; Family membership YP_692514.1 identified by match to PFAM protein family HMMPF01734 InterPro: Uncharacterized protein family UPF0028 YP_692515.1 CBS domain protein identified by match to PFAM protein family HMMPF03471 contains the DUF 21 domain; Function unclear YP_692516.1 identified by sequence similarity; Conserved hypothetical protein YP_692517.1 identified by match to PFAM protein family HMMPF00448 InterPro: Signal recognition particle protein; High confidence in function and specificity YP_692518.1 (ribosomal protein S16) identified by sequence similarity; InterPro: Ribosomal protein S16; High confidence in function and specificity YP_692519.1 identified by sequencesimilarity; InterPro: RimM; High confidence in function and specificity YP_692520.1 identified by sequence similarity; InterPro: tRNA (guanine-N1-)-methyltransferase; High confidence in function and specificity YP_692521.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site YP_692522.1 identified by match to PFAM protein family HMMPF04226 YP_692523.1 identified by sequence similarity; Homologous to Abo_2171; InterPro: Phage integrase; High confidence in function and specificity YP_692524.1 (thiol:disulfide interchange protein DsbC) identified by sequence similarity; High confidence in function and specificity YP_692525.1 (aminotransferase, ) identified by match to TIGR protein family HMMTIGR01141 and PFAM protein family HMMPF00155; InterPro: Aminotransferases class-I; Family membership YP_692526.1 catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine YP_692527.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine YP_692528.1 (choline/carnitine/betaine transporter familyprotein) identified by match to PFAM protein family HMMPF02028 InterPro: BCCT transporter IPRO0060: These prokaryotic transport proteins belong to a family known as BCCT (for Betaine /Carnitine / Choline Transporters) and are specific for compounds containing a quaternary nitrogen atom. The BCCT proteins contains 12 transmembrane regions and are energized by proton symport. They contains a conserved region with four tryptophans in their central region.; Specificity unclear YP_692529.1 identified by sequence similarity YP_692532.1 identified by match to PFAM protein family HMMPF02515 InterPro: CAIB/BAIF family; Family membership YP_692533.1 identified by match to TIGR protein family HMMTIGR00186 InterPro: tRNA/rRNA methyltransferase; Family membership YP_692535.1 serine endopeptidase identified by sequence similarity; InterPro: Serine proteases trypsin family; Specificity unclear YP_692536.1 (trx-1) (thioredoxin) identified by match to PFAM protein family HMMPF00085 InterPro: Thioredoxin; High confidence in function and specificity YP_692537.1 (alcohol dehydrogenase zinc-containing) identified by sequencesimilarity; Family membership YP_692540.1 (phosphoribosylglycinamide formyltransferase 2) identified by sequencesimilarity; InterPro: ATP-grasp domain; Family membership YP_692541.1 (Cytidine and deoxycytidylate deaminase) identified by sequence similarity; InterPro: Cytidine and deoxycytidylate deaminase zinc-binding region; Family membership YP_692542.1 (outer membrane protein OprF; OmpA domain protein) identified by sequence similarity; InterPro: Bacterial outer membrane protein; High confidence in function and specificity YP_692549.1 identified by sequencesimilarity; High confidence in function and specificity YP_692551.1 (DNA-binding heavy metal response regulator, ) identified by match to TIGR protein family HMMTIGR01387 InterPro: Response regulator receiver domain; Specificity unclear YP_692552.1 identified by match to PFAM protein family HMMPF00165 InterPro: ThiJ/PfpI family; Specificity unclear YP_692553.1 acyl-CoA dehydrogenase family protein identified by match to PFAM protein family HMMPF00441 InterPro: Acyl-CoA dehydrogenase; Specificity unclear YP_692554.1 (3-oxoacyl-(acyl-carrier-protein) synthase I) identified by match to PFAM protein family HMMPF02801 InterPro: Beta-ketoacyl synthase; High confidence in function and specificity YP_692555.1 catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to 2,3-decenoyl-ACP or 3,4-decenoyl-ACP YP_692556.1 identified by match to TIGR protein family HMMTIGR00353 InterPro: Cytochrome c-type biogenesis protein (CcmF); High confidence in function and specificity YP_692557.1 identified by sequence similarity; InterPro: Periplasmic protein thiol:disulfide oxidoreductase DsbE; High confidence in function and specificity YP_692558.1 Family membership YP_692559.1 Family membership YP_692560.1 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP YP_692562.1 identified by sequence similarity; InterPro: Bacterioferritin; High confidence in function and specificity YP_692563.1 OadG, oxaloacetate decarboxylase, gamma chain; Family membership YP_692564.1 catalyzes the formation of pyruvate from oxaloacetate YP_692565.1 Oxaloacetate decarboxylase beta chain; High confidence in function and specificity YP_692566.1 (conserved hypothetical protein) identified by sequencesimilarity YP_692570.1 membrane protein identified by match to PFAM protein family HMMPF04306 InterPro: General substrate transporters; Function unclear YP_692571.1 Function unclear YP_692572.1 identified by sequencesimilarity; InterPro: Binding-protein-dependent transport systems inner membrane component; Family membership YP_692573.1 High confidence in function and specificity YP_692575.1 (nitrite reductase) identified by sequence similarity; InterPro: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; High confidence in function and specificity YP_692578.1 oxidoreductase (acting on the CH-NH group of donors with NAD+ or NADP+ as acceptor (flavohemoprotein)) identified by sequence similarity; InterPro: Globin; Function unclear YP_692579.1 identified by sequence similarity; InterPro: Response regulator receiver domain; High confidence in function and specificity YP_692580.1 identified by sequence similarity; Hypothetical protein YP_692581.1 catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine YP_692582.1 (metR-1) identified by sequence similarity; InterPro: Bacterial regulatory protein LysR family; High confidence in function and specificity YP_692585.1 identified by sequencesimilarity YP_692587.1 (GGDEF family protein) identified by match to PFAM protein family HMMPF00990 YP_692589.1 Function unclear YP_692590.1 Heme exporter protein A (Cytochrome c-type biogenesis ATP-binding protein ccmA). (aapP) (general amino acid ABC transporter ATP-bindingprotein) identified by match to TIGR protein family HMMTIGR00968; High confidence in function and specificity YP_692591.1 Heme exporter protein B (Cytochrome c-type biogenesis protein ccmB). (heme ABC export system permease protein CcmB) identified by match to TIGR protein family HMMTIGR01190; High confidence in function and specificity YP_692592.1 Heme exporter protein C (Cytochrome c-type biogenesis protein ccmC). (heme ABC export system permease protein CcmC) identified by sequencesimilarity; InterPro: Cytochrome c assembly protein; High confidence in function and specificity YP_692593.1 (cytochrome c-type biogenesis protein CcmD) identified by sequence similarity; High confidence in function and specificity YP_692594.1 identified by sequence similarity; InterPro: CcmE/CycJ proteins; High confidence in function and specificity YP_692595.1 ribosomal protein S6 modification protein-relatedprotein identified by sequence similarity; Function unclear YP_692596.1 transferase (transferring alkyl or aryl groups, other than methyl groups) family protein identified by match to PFAM protein family HMMPF00043 InterPro: Glutathione S-transferase C terminus; Specificity unclear YP_692597.1 identified by sequence similarity; Family membership YP_692598.1 (ATP-binding cassette (ABC) transporter, permease protein, ) identified by match to PFAM protein family HMMPF00005 InterPro: AAA ATPase superfamily; Family membership YP_692599.1 (ABC transporter, permease protein, ) identified by match to PFAM protein family HMMPF04306 InterPro: ABC 2 transport system integral membrane protein; Family membership YP_692600.1 catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) in queuosine biosynthesis YP_692601.1 ( p-aminobenzoyl-glutamate transporter) identified by match to PFAM protein family ABG_transport; Family membership YP_692604.1 nitroreductase family protein identified by match to PFAM protein family HMMPF00881 InterPro: Nitroreductase family; Family membership YP_692605.1 adenylate cyclase PA3217; Specificity unclear YP_692606.1 similar to: SP:Q00593 SP:P17444 and SP:P54223; identified by sequence similarity; identified by match to PFAM protein families HMMPF00732 and HMMPF05199; InterPro: Glucose-methanol-choline (GMC) oxidoreductase; Specificity unclear YP_692608.1 identified by sequencesimilarity; InterPro: HNH nuclease YP_692609.1 (hypothetical protein) identified by match to PFAM protein family HMMPF04097 YP_692615.1 InterPro: Glycosyl transferases group 1 YP_692616.1 identified by sequence similarity; predicted membrane protein YP_692618.1 (extracellular protein ) identified by sequencesimilarity YP_692619.1 conserved hypothetical protein identified by Glimmer2; Function unclear YP_692620.1 (pbpC) (penicillin-binding protein 1C) identified by sequencesimilarity; InterPro: Penicillin binding protein transpeptidase domain; High confidence in function and specificity YP_692621.1 identified by match to PFAM protein family HMMPF00384 InterPro: Prokaryotic molybdopterin oxidoreductases; High confidence in function and specificity YP_692622.1 Function unclear YP_692623.1 identified by sequence similarity; Family membership YP_692624.1 identified by sequence similarity YP_692625.1 (polysaccharide export protein ) identified by sequencesimilarity; InterPro: Polysaccharide export protein; Specificity unclear YP_692626.1 wzb (protein-tyrosine-phosphatase) identified by match to PFAM protein family HMMPF01451; High confidence in function and specificity YP_692627.1 tyrosine-protein kinase Wzc; Family membership; deleted EC_number 2.7.1.112 YP_692628.1 (capsular polysaccharide biosynthesis protein/UDP-glucose dehydrogenase) identified by match to PFAM protein family HMMPF00984 InterPro: UDP-glucose/GDP-mannose dehydrogenase family The UDP-glucose/GDP-mannose dehydrogenases are a small group of enzymes which possesses the ability to catalyze the NAD-dependent 2-fold oxidation of an alcholol to an acid without the release of an aldehyde intermediate; Family membership YP_692629.1 identified by match to TIGR protein family HMMTIGR01746; InterPro: Nucleoside-diphosphate dependent epimerase/dehydratase family; Specificity unclear YP_692630.1 identified by match to TIGR protein family HMMTIGR01746 InterPro: NAD dependent epimerase/dehydratase family; High confidence in function and specificity YP_692631.1 (rfbd) , (dTDP-4-keto-L-rhamnose reductase),(dTDP-6-deoxy-L-mannose dehydrogenase), (dTDP-L-rhamnose synthetase). identified by match to TIGR protein family HMMTIGR01746; High confidence in function and specificity YP_692632.1 (acetyltransferase, ) identified by sequence similarity; Family membership YP_692633.1 (rfba) , (dTDP-glucosesynthase), (dTDP-glucose pyrophosphorylase). identified by sequence similarity; InterPro: ADP-glucose pyrophosphorylase; High confidence in function and specificity YP_692634.1 (dTDP-4-dehydrorhamnose 3,5-epimerase familyprotein),(dTDP-4-keto-6-deoxyglucose 3,5-epimerase) (dTDP-L-rhamnose synthetase). identified by sequencesimilarity; InterPro: dTDP-4-dehydrorhamnose 35-epimerase; High confidence in function and specificity YP_692635.1 (imidazolonepropionase) identified by sequence similarity; InterPro: Polysaccharide biosynthesis protein; Specificity unclear YP_692637.1 identified by sequencesimilarity; InterPro: Domain of unknown function DUF33; Family membership YP_692638.1 (glycosyl transferase group 2 family protein) identified by match to TIGR protein family HMMTIGR01556 InterPro: Glycosyl transferase family 2; Family membership YP_692639.1 identified by match to PFAM protein family HMMPF00534 InterPro: Glycosyl transferases group 1; High confidence in function and specificity YP_692640.1 identified by match to PFAM protein family HMMPF00534 InterPro: Glycosyl transferases group 1; Family membership YP_692644.1 (glycosyl transferase probable) group 1 family protein identified by sequence similarity; InterPro: Glycosyl transferases group 1; Family membership YP_692645.1 identified by match to PFAM protein family HMMPF02397 This Pfam family represents a conserved region from a number of different bacterial sugar transferases, involved in diverse biosynthesis pathways.; Family membership YP_692646.1 (lpxA) (acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase) identified by match to PFAM protein family HMMPF00132 catalytic activity: (r)-3-hydroxytetradecanoyl-[acyl-carrier protein] + udp-n-acetylglucosamine = [acyl-carrier protein] + udp-3-o-(3-hydroxytetradecanoyl)-n-acetylglucosamine.; High confidence in function and specificity YP_692647.1 (aminotransferase class I) identified by match to TIGR protein family HMMTIGR01265 InterPro: DegT/DnrJ/EryC1/StrS family The members of this family are probably all pyridoxal-phosphate-dependent aminotransferase enzymes with a variety of molecular functions. This enzyme is probably involved in the (regulation) of the cell wall biogenesis; High confidence in function and specificity YP_692648.1 identified by sequence similarity; InterPro: Polysaccharide biosynthesis protein CapD type; Family membership YP_692649.1 transporter sodium/sulfate symporter family, identified by match to PFAM protein family HMMPF03600, TMHMM: reporting 12 transmembrane helices; Family membership YP_692650.1 (adenylylphosphosulfate kinase) identified by sequencesimilarity; InterPro: Adenylylsulfate kinase; High confidence in function and specificity YP_692652.1 (GDP-mannose 6-dehydrogenase) identified by sequence similarity; InterPro: UDP-glucose/GDP-mannose dehydrogenase family; High confidence in function and specificity YP_692654.1 identified by match to TIGR protein family HMMTIGR01099 InterPro: ADP-glucose pyrophosphorylase; High confidence in function and specificity YP_692655.1 (UDP-glucose dehydrogenase ) identified by match to PFAM protein family HMMPF00984 InterPro: UDP-glucose/GDP-mannose dehydrogenase family; Specificity unclear YP_692656.1 identified by sequencesimilarity; InterPro: Phosphoglucose isomerase (PGI); High confidence in function and specificity YP_692657.1 identified by sequence similarity; InterPro: Phosphoglucomutase and phosphomannomutase family; High confidence in function and specificity YP_692658.1 (UDP-glucose-4-epimerase),(Galactowaldenase), . identified by match to TIGR protein family HMMTIGR01746 InterPro: NAD dependent epimerase/dehydratase family; High confidence in function and specificity YP_692659.1 InterPro: Polysaccharide biosynthesis protein Members of this family are integral membrane proteins. Many members of the family are implicated in production of polysaccharide. The family includes RfbX part of the O antigen biosynthesis operon; Family membership YP_692660.1 InterPro: Sulfotransferase YP_692661.1 (glycosyl transferase group 2 family protein) identified by match to PFAM protein family HMMPF00535 InterPro: Glycosyl transferase family 2 Diverse family, transferring sugar from UDP-glucose, UDP-N-acetyl-galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids.; Family membership YP_692662.1 identified by sequencesimilarity; InterPro: Glycosyl transferase family 2; Hypothetical protein YP_692664.1 (aspartate aminotransferase, transaminase A) identified by sequence similarity; identified by match to PFAM protein family HMMPF00155 InterPro: Aminotransferases class-I; High confidence in function and specificity YP_692665.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion YP_692666.1 identified by match to PFAM protein family HMMPF04401; Family membership YP_692667.1 identified by match to PFAM protein family HMMPF02483 InterPro: SMC family C-terminal domain; High confidence in function and specificity YP_692668.1 interacts directly with the cell division protein ftsZ; probable receptor for the septal ring structure, may anchor it to the inner-membrane YP_692669.1 this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB YP_692670.1 Function unclear YP_692671.1 (oxidoreductase FMN-binding) identified by match to PFAM protein family HMMPF00724 YP_692672.1 (phenazine biosynthesis protein PhzF family) identified by match to PFAM protein family HMMPF02567 InterPro: Phenazine biosynthesis PhzC/PhzF protein YP_692673.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, tyrosine sensitive YP_692674.1 oxidoreductase (acting on the CH-OH group of donors with NAD+ or NADP+ as acceptor) family identified by sequence similarity; InterPro: Short-chain dehydrogenase/reductase (SDR) superfamily; Family membership YP_692675.1 oxidoreductase identified by match to PFAM protein family HMMPF01575 InterPro: MaoC-like dehydratase domain; Family membership YP_692676.1 (phosphoglycerate mutase family protein) identified by match to TIGR protein family HMMTIGR00249; InterPro: Phosphoglycerate mutase family; Family membership YP_692677.1 acyl-CoA dehydrogenase identified by match to PFAM protein family HMMPF00441 InterPro: Acyl-CoA dehydrogenase; Specificity unclear YP_692678.1 identified by sequencesimilarity YP_692679.1 oxidoreductase (short-chaindehydrogenase/reductase family) identified by match to PFAM protein family HMMPF00106 InterPro: Short-chain dehydrogenase/reductase (SDR) superfamily; Family membership YP_692680.1 oxidoreductase (acting on the CH-OH group of donors with NAD+ or NADP+ as acceptor) identified by sequencesimilarity; InterPro: Short-chain dehydrogenase/reductase (SDR) superfamily; Family membership YP_692681.1 predicted metal-dependent hydrolase YP_692682.1 identified by match to TIGR protein family HMMTIGR01722 InterPro: Aldehyde dehydrogenase family; Specificity unclear YP_692683.1 InterPro: Outer membrane efflux protein probably a component that vonfers multidrug resistance. could also be implicated in the secretion of the siderophore, pyoverdine. probably involved in the efflux of the siderophore across the outer membrane; Hypothetical protein YP_692684.1 identified by sequence similarity; InterPro: Hydrophobe/amphiphile efflux-1 HAE1; Family membership YP_692685.1 (multidrug/solvent RND membrane fusion protein) identified by sequence similarity; InterPro: HlyD family secretion protein; High confidence in function and specificity YP_692686.1 identifiedby sequence similarity; InterPro: Bacterial regulatory proteins TetR family; Specificity unclear YP_692687.1 2-dehydropantoate 2-reductase identified by match to TIGR protein family HMMTIGR00745 InterPro: Ketopantoate reductase ApbA/PanE; Specificity unclear YP_692688.1 identified by sequencesimilarity YP_692689.1 shows identity (ca. 40 ) to uncharacterized relative of glutathione S-transferase, MAPEG superfamily YP_692690.1 D-amino acid oxidase family protein identified by match to TIGR protein family HMMTIGR00136 InterPro: NAD binding site; Family membership YP_692692.1 phosphotransferases (with a nitrogenous group as acceptor) identified by match to PFAM protein family HMMPF04171 InterPro: Histidine kinase C-terminal; Family membership YP_692693.1 methyltransferase identified by match to TIGR protein family HMMTIGR00740 InterPro: SAM (and some other nucleotide) binding motif; Conserved hypothetical protein YP_692694.1 (methyltransferase ) identified by match to TIGR protein family HMMTIGR00452 InterPro: SAM (and some other nucleotide) binding motif YP_692700.1 Family membership YP_692701.1 (hydrolase ) identified by match to PFAM protein family HMMPF00753 InterPro: Metallo-beta-lactamase superfamily shows some identity to Zn-dependet hydrolases YP_692703.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation YP_692704.1 identified by match to PFAM protein family HMMPF00441; High confidence in function and specificity YP_692705.1 activates fatty acids by binding to coenzyme A; may be involved in acyclic terpene utilization YP_692706.1 identified by match to TIGR protein family HMMTIGR00514 InterPro: Carbamoyl-phosphate synthase; High confidence in function and specificity YP_692707.1 (enoyl-CoA hydratase/isomerase FadB1x) identified by sequence similarity; InterPro: Enoyl-CoA hydratase/isomerase; High confidence in function and specificity YP_692708.1 identified by sequencesimilarity; InterPro: Acyl-CoA dehydrogenase; Family membership YP_692709.1 identified by sequencesimilarity; InterPro: Carboxyl transferase family; High confidence in function and specificity YP_692710.1 oxidoreductase identified by match to TIGR protein family HMMTIGR01500 InterPro: Short-chain dehydrogenase/reductase (SDR) superfamily; Family membership YP_692712.1 transcriptional regulator TetR family identified by match to PFAM protein family HMMPF00440 InterPro: Bacterial regulatory proteins TetR family; Family membership YP_692714.1 InterPro: Cyclic nucleotide-binding domain; Family membership YP_692715.1 (nicotinamide adenine dinucleotide kinase ) identified by match to PFAM protein family HMMPF01513; High confidence in function and specificity YP_692718.1 (aminopeptidase N, alpha-aminoacylpeptide hydrolase) identified by sequence similarity; InterPro: Aminopeptidase N APN (CD13); High confidence in function and specificity YP_692721.1 identified by match to PFAM protein family HMMPF02012 InterPro: BNR repeat Uncharacterized protein related to plant photosystem II stability; Family membership YP_692722.1 identified by sequence similarity; InterPro: HMGCR/Patched 5TM box; Conserved hypothetical protein YP_692723.1 (dihydroorotate dehydrogenase) identified by match to PFAM protein family HMMPF01180 InterPro: Dihydroorotate dehydrogenase; High confidence in function and specificity YP_692724.1 identify by similarity to PFAM protein family PF04957; High confidence in function and specificity YP_692725.1 catalyzes the N2-methyl guanosine modification of the G2445 residue of 23S rRNA YP_692727.1 identified by sequencesimilarity; InterPro: Uncharacterized protein family UPF0006; Family membership YP_692729.1 (lexA-1) identified by sequence similarity; InterPro: LexA DNA binding domain; High confidence in function and specificity YP_692730.1 InterPro: Cyclic nucleotide-binding domain YP_692731.1 uspA identified by match to PFAM protein family HMMPF00582 InterPro: Universal stress protein (Usp); Family membership YP_692732.1 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity YP_692736.1 transcriptional regulator TetR family identified by match to PFAM protein family HMMPF00440 InterPro: Bacterial regulatory proteins TetR family; Specificity unclear YP_692738.1 (N-acetyl-beta-hexosaminidase) identified by sequence similarity; InterPro: Glycoside hydrolase family; High confidence in function and specificity YP_692739.1 identified by sequencesimilarity; InterPro: Uncharacterized protein family UPF0003 YP_692740.1 identified by sequence similarity; InterPro: Phosphoribosyl transferase; High confidence in function and specificity YP_692741.1 (heat shock protein ) identified by sequence similarity; InterPro: Purine and other phosphorylases family 2; High confidence in function and specificity YP_692742.1 (metal ion transporter ) identified by match to PFAM protein family HMMPF03471 InterPro: Domain of unknown function DUF21; Family membership YP_692743.1 (cysteine synthase A, O-acetylserine sulfhydrylase A, O- acetylserine (thiol)-lyase A, sulfate starvation-induced protein 5) identified by sequencesimilarity; InterPro: Pyridoxal-5-phosphate-dependent enzymes beta family; High confidence in function and specificity YP_692744.1 (conserved hypothetical protein TIGR00275) identified by match to TIGR protein family HMMTIGR00275 InterPro: HI0933-like protein This is a family of conserved hypothetical proteins that may include proteins with a dinucleotide-binding motif (Rossman fold), including oxidoreductases and dehydrogenases YP_692746.1 oxidoreductase (short-chaindehydrogenase/reductase family) identified by match to PFAM protein family HMMPF00106; Family membership YP_692748.1 identified by match to TIGR protein family HMMTIGR00643 InterPro: Transcription-repair coupling factor; High confidence in function and specificity YP_692749.1 identified by match to TIGR protein family HMMTIGR00189 InterPro: Acyl-CoA thioesterase; High confidence in function and specificity YP_692750.1 (argD) (acetylornithine aminotransferase) identified by sequence similarity YP_692751.1 catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate; involved in growth under gluconeogenic conditions and in glycolytic activity at high ATP concentrations in Corynebacterium; NAD and NADP dependent YP_692752.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm YP_692753.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm YP_692754.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm YP_692755.1 Part of the NQR complex which catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm YP_692756.1 Part of the NQR complex which consists of NqrA, NqrB, NqrC, NqrD, NqrE and NqrF; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm; NqrE is probably involved in the second step, the conversion of ubisemiquinone to ubiquinol. YP_692757.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm YP_692758.1 thiamine biosynthesis lipoprotein identified by sequencesimilarity; InterPro: ApbE family; Family membership YP_692759.1 Protein of family with unknown function (DUF539) YP_692760.1 (acetyltransferase GNAT family, ) identified by match to TIGR protein family HMMTIGR01575 InterPro: GCN5-related N-acetyltransferase; Family membership YP_692761.1 identified by sequence similarity YP_692762.1 identified by match to PFAM protein family HMMPF03009 InterPro: Glycerophosphoryl diester phosphodiesterase; Conserved hypothetical protein YP_692764.1 shows homology to glycosyl transferase group 1 family protein YP_692765.1 identified by sequence similarity YP_692766.1 identified by sequence similarity; InterPro: Carbon-nitrogen hydrolase This family contains nitrilases that break carbon-nitrogen bonds and appear to be involved in the reduction of organic nitrogen compounds and ammonia production; Family membership YP_692767.1 identified by match to PFAM protein family HMMPF04371; Family membership YP_692769.1 lipoprotein releasing system permease protein) identified by sequence similarity; transport lipids targeted to the outer membrane across the inner membrane.; Conserved hypothetical protein YP_692770.1 (ATP-binding cassette (ABC) transporters, permease protein, ) identified by match to TIGR protein family HMMTIGR00968; Family membership YP_692772.1 (DNA internalization-related competence protein ComEC/Rec2) identified by match to PFAM protein family HMMPF03772 InterPro: DNA internalization-related competence protein ComEC/Rec2 Possibly exported; Family membership YP_692773.1 MotA/TolQ/ExbB proton channel family protein identified by match to PFAM protein family HMMPF01618; High confidence in function and specificity YP_692774.1 InterPro: Biopolymer transport protein ExbD/TolR; Specificity unclear YP_692775.1 (ATP-binding cassette (ABC) transporters, permease protein, ) identified by sequence similarity; InterPro: ABC transporter transmembrane region; High confidence in function and specificity YP_692776.1 tetraacyldisaccharide 4'-kinase (EC 2.7.1.130) (lipid a 4'-kinase).; High confidence in function and specificity YP_692777.1 (3-deoxy-D-manno-octulosonatecytidylyltransferase) 3-deoxy-manno-octulosonate cytidylyltransferase (EC 2.7.7.38) (cmp-kdo synthetase) (cmp-2-keto-3-deoxyoctulosonic acid synthetase) (cks).; High confidence in function and specificity YP_692778.1 pt identified by match to PFAM protein family HMMPF01451 InterPro: Low molecular weight phosphotyrosine protein phosphatase; High confidence in function and specificity YP_692779.1 (udp-n- acetylmuramate dehydrogenase); identify by similarity to PFAM protein family PF01565 and PF02873; High confidence in function and specificity YP_692780.1 phosphoric diester hydrolase (ribonuclease E) identified by sequencesimilarity; InterPro: Ribonuclease E and G; Specificity unclear YP_692781.1 (Pseudouridylate synthase)(Uracil hydrolyase).; High confidence in function and specificity YP_692782.1 (hydrolase haloacid dehalogenase-like family) identified by sequencesimilarity; InterPro: Haloacid dehalogenase/epoxide hydrolase family; Family membership YP_692783.1 peptidase S49 family identified by match to PFAM protein family HMMPF01343 InterPro: Signal peptide peptidase SppA 36K type; Function unclear YP_692784.1 identified by match to PFAM protein family HMMPF02545 InterPro: Maf-like protein; High confidence in function and specificity YP_692785.1 identified by sequence similarity; InterPro: DUF177 YP_692786.1 identified by sequencesimilarity; High confidence in function and specificity YP_692787.1 identified by sequencesimilarity; InterPro: Fatty acid synthesis plsX protein; Family membership YP_692788.1 identified by sequencesimilarity; InterPro: Acyl transferase domain; High confidence in function and specificity YP_692789.1 identified by sequence similarity; InterPro: Short-chain dehydrogenase/reductase (SDR) superfamily; High confidence in function and specificity YP_692790.1 identified by match to PFAM protein family HMMPF00550 InterPro: Phosphopantetheine attachment site; Family membership YP_692791.1 (3-oxoacyl-(acyl-carrier-protein) synthase II) identified by sequencesimilarity; InterPro: Beta-ketoacyl synthase; High confidence in function and specificity YP_692792.1 identified by sequence similarity; InterPro: Aminotransferases class-IV; High confidence in function and specificity YP_692793.1 (conserved hypothetical protein TIGR00247) identified by match to TIGR protein family HMMTIGR00247 InterPro: DUF175 YP_692794.1 (dTMP kinase; thymidine monophosphate kinase; thymidylate kinasethiol:disulfide interchange protein DsbD) identified by match to PFAM protein family HMMPF03772 InterPro: Thymidylate kinase; High confidence in function and specificity YP_692795.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA YP_692796.1 type IV pilus biogenesis protein, identified by sequence similarity to Pseudomonas syringae pv. tomato str. DC3000; High confidence in function and specificity YP_692797.1 identified by match to PFAM protein family HMMPF01026 InterPro: Uncharacterized protein family UPF0006; Family membership YP_692798.1 identified by match to PFAM protein family HMMPF02646 InterPro: DUF195 shows 46 38dentitie to a rumC family protein. This family contains several bacterial RmuC DNA recombination proteins. The function of the RMUC protein is unknown but it is suspected that it is either a structural protein that protects DNA against nuclease action, or is itself involved in DNA cleavage at the regions of DNA secondary structures YP_692799.1 InterPro: Serine proteases trypsin family; Family membership YP_692801.1 (aminotransferase, ) identified by sequencesimilarity; InterPro: Aminotransferase class-V; Family membership YP_692802.1 transcriptional regulator TetR family identified by match to PFAM protein family HMMPF00440 InterPro: Bacterial regulatory proteins TetR family; Family membership YP_692804.1 (pnk) identified by sequencesimilarity; InterPro: Serine/Threonine protein kinase; High confidence in function and specificity YP_692805.1 identified by sequence similarity InterPro: General substrate transporters; High confidence in function and specificity YP_692806.1 NirB; nitrite reductase [NAD(P)H] identified by sequence similarity; InterPro: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; High confidence in function and specificity YP_692807.1 (nitrite reductase) identified by sequence similarity; InterPro: Rieske iron-sulfur protein 2Fe-2S subunit; High confidence in function and specificity YP_692808.1 (NAD(P)H-nitrite reductase family protein identified by sequence similarity; InterPro: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Family membership YP_692809.1 (probable nitrate reductase large subunit) identified by sequencesimilarity; InterPro: Prokaryotic molybdopterin oxidoreductases; Family membership YP_692811.1 (cation transporter VIC family) identified by match to PFAM protein family HMMPF00914 InterPro: Cation channels (non-ligand gated); Family membership YP_692812.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive YP_692813.1 Modulates the activities of several enzymes which are inactive in their acetylated form YP_692815.1 identified by sequence similarity; InterPro: Carbon-nitrogen hydrolase; Family membership YP_692816.1 identified by sequence similarity YP_692817.1 identified by sequence similarity; InterPro: Flavin-containing monooxygenase (FMO); Family membership YP_692818.1 (Ribosomal small subunit pseudouridine synthase A ) identified by match to PFAM protein family HMMPF01479 InterPro: Conserved hypothetical protein 93; High confidence in function and specificity YP_692819.1 identified by sequencesimilarity; InterPro: Bacterial regulatory protein LysR family; Specificity unclear YP_692820.1 electron transfer flavoprotein-ubiquinone oxidoreductase, (electron transfer flavoprotein-ubiquinoneoxidoreductase ) identified by match to PFAM protein family HMMPF03545; High confidence in function and specificity YP_692821.1 identified by sequencesimilarity; InterPro: Electron transfer flavoprotein beta-subunit; High confidence in function and specificity YP_692822.1 identified by sequencesimilarity; InterPro: Electron transfer flavoprotein alpha-subunit; High confidence in function and specificity YP_692823.1 identified by match to PFAM protein family HMMPF00106 InterPro: Short-chain dehydrogenase/reductase (SDR) superfamily; Family membership YP_692824.1 outer membrane siderophore receptor identified by sequence similarity; InterPro: TonB-dependent receptor protein; Function unclear YP_692827.1 identified by match to PFAM protein family HMMPF04168 YP_692828.1 identified by match to PFAM protein family HMMPF01841 InterPro: Transglutaminase-like superfamily; Family membership YP_692829.1 conserved hypothetical protein identified by match to PFAM protein family HMMPF00227 InterPro: Multispecific proteasome proteases YP_692830.1 (conserved hypothetical protein) identified by match to PFAM protein family HMMPF04185 InterPro: Sulfatase YP_692831.1 (tesA)(acyl-CoA thioesterase II) identified by match to PFAM protein family HMMPF02551; High confidence in function and specificity YP_692832.1 identified by match to TIGR protein family HMMTIGR00530 InterPro: Phospholipid and glycerol acyltransferase (from motifs_6.msf); Family membership YP_692833.1 sensor histidine kinase/response regulator identified by sequencesimilarity; InterPro: GAF domain; Function unclear YP_692834.1 (acdP) identified by sequence similarity; High confidence in function and specificity YP_692835.1 (membrane protein, ) identified by match to PFAM protein family HMMPF00892; Function unclear YP_692838.1 identified by sequencesimilarity; High confidence in function and specificity YP_692839.1 identified by sequencesimilarity; InterPro: ParA family ATPase; High confidence in function and specificity YP_692840.1 identified by sequence similarity; High confidence in function and specificity YP_692841.1 functions in fatty acid oxidation; converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA YP_692842.1 identified by match to PFAM protein family HMMPF00085 InterPro: Thioredoxin; Function unclear YP_692843.1 identified by sequence similarity; identified by match to PFAM protein family HMMPF00543 InterPro: Nitrogen regulatory protein P-II; High confidence in function and specificity YP_692844.1 Ammonium transporter, Ammonium Transporter Family,amt: ammonium transporter; High confidence in function and specificity YP_692846.1 identified by sequence similarity; High confidence in function and specificity YP_692847.1 (helicase ) identified by match to TIGR protein family HMMTIGR01407; Specificity unclear YP_692848.1 identified by sequence similarity; InterPro: Glycoprotease (M22) metallo-protease family YP_692849.1 (conserved hypothetical protein TIGR00051) identified by match to PFAM protein family HMMPF03061 InterPro: 4-hydroxybenzoyl-CoA thioesterase family active site YP_692850.1 identified by match to PFAM protein family HMMPF02673 InterPro: Bacitracin resistance protein BacA; Function unclear YP_692852.1 PlsB; catalyzes the formation of 1-acyl-sn-glycerol 3-phosphate by transfering the acyl moiety from acyl-CoA YP_692853.1 identified by match to PFAM protein family HMMPF04261; Family membership YP_692854.1 aldehyde dehydrogenase family protein identified by match to TIGR protein family HMMTIGR01722 InterPro: Aldehyde dehydrogenase family; Specificity unclear YP_692855.1 efflux transporter permease protein Specificity unclear YP_692856.1 (efflux transporter, membrane fusion protein, ) identified by match to TIGR protein family HMMTIGR01730 InterPro: HlyD family secretion protein; Family membership YP_692857.1 dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica. YP_692858.1 (N-succinyltransferase ) identified by match to TIGR protein family HMMTIGR00965; High confidence in function and specificity YP_692859.1 Conserved hypothetical protein ArsC related, Pfam: ArsC family, arsC_related: conserved hypothetical protein YP_692860.1 catalyzes the formation of succinyldiaminopimelate from N-succinyl-2-amino-6-ketopimelate YP_692861.1 Catalyzes the uridylylation or deuridylylation of the PII nitrogen regulatory protein YP_692862.1 identified by match to PFAM protein family HMMPF00557 and TIGR FAM TIGR00500 InterPro: Methionine aminopeptidase subfamily 1; Family membership YP_692863.1 identified by sequencesimilarity; InterPro: Ribosomal protein S2; High confidence in function and specificity YP_692864.1 (translation elongation factor Ts) identified by sequencesimilarity; InterPro: Elongation factor Ts; High confidence in function and specificity YP_692865.1 Catalyzes the phosphorylation of UMP to UDP YP_692866.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs YP_692867.1 identified by sequence similarity; InterPro: UDP pyrophosphate synthetase family; High confidence in function and specificity YP_692868.1 (phosphatidate cytidylyltransferase, CDP-diglyceride synthetase) identified by match to PFAM protein family HMMPF01148 InterPro: Phosphatidate cytidylyltransferase (CDP-diglyceride synthetase); High confidence in function and specificity YP_692869.1 catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate YP_692870.1 identified by match to PFAM protein family HMMPF02163 InterPro: membrane-associated zinc metalloprotease; Function unclear YP_692871.1 (bacterial surface antigen family protein) identified by match to PFAM protein family HMMPF01103 InterPro: Bacterial surface antigen (D15); Family membership YP_692872.1 (outer membrane protein OmpH) identified by match to PFAM protein family HMMPF03938; Function unclear YP_692873.1 identified by match to PFAM protein family HMMPF00132 udp-3-o-(3-hydroxytetradecanoyl)glucosamine + (r)-3-hydroxytetradecanoyl-[acyl-carrier protein] = udp-2,3-bis(3- hydroxytetradecanoyl)glucosamine + [acyl-carrier protein]; High confidence in function and specificity YP_692874.1 identified by sequencesimilarity; InterPro: Bacterial thioester dehydrase; High confidence in function and specificity YP_692875.1 (acyl-[acyl-carrier-protein]--UDP-N-acetylglucosami ne O-acyltransferase); High confidence in function and specificity YP_692876.1 High confidence in function and specificity YP_692877.1 (ribonuclease HII) identified by sequence similarity; InterPro: Ribonuclease HII and HIII; High confidence in function and specificity YP_692878.1 catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase YP_692879.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein YP_692880.1 identified by sequence similarity; Specificity unclear YP_692881.1 High confidence in function and specificity YP_692882.1 CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer YP_692883.1 catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis YP_692884.1 (enolase (2-phosphoglycerate dehydratase) (2-phospho-d-glycerate hydro-lyase)) identified by sequencesimilarity; InterPro: Enolase; High confidence in function and specificity YP_692885.1 identified by sequencesimilarity YP_692886.1 identified by match to TIGR protein family HMMTIGR00453 InterPro: 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; High confidence in function and specificity YP_692887.1 identified by match to PFAM protein family HMMPF02542 InterPro: 2C-methyl-D-erythritol 24-cyclodiphosphate synthase; High confidence in function and specificity YP_692888.1 conserved hypothetical protein identified by match to TIGR protein family HMMTIGR00094 InterPro: Uncharacterized protein family UPF0024 YP_692889.1 (protein-L-isoaspartate O-methyltransferase) identified by match to TIGR protein family HMMTIGR00080 InterPro: Protein-L-isoaspartate(D-aspartate) O-methyltransferase; High confidence in function and specificity YP_692891.1 (lipoprotein NlpD) identified by sequence similarity; InterPro: Peptidase family M23/M37; Function unclear YP_692892.1 identified by match to TIGR protein family HMMTIGR01297 InterPro: Cation efflux family; Family membership YP_692894.1 identified by sequence similarity; InterPro: Glucose-methanol-choline (GMC) oxidoreductase; Family membership YP_692895.1 (alcohol dehydrogenase iron-containing) identified by match to PFAM protein family HMMPF00465 InterPro: Iron-containing alcohol dehydrogenase; High confidence in function and specificity YP_692896.1 (conserved hypothetical protein TIGR00051) identified by match to PFAM protein family HMMPF03061 InterPro: 4-hydroxybenzoyl-CoA thioesterase family active site YP_692897.1 identified by sequence similarity; InterPro: D-isomer specific 2-hydroxyacid dehydrogenase; High confidence in function and specificity YP_692899.1 (conserved hypothetical protein TIGR00147) identified by sequencesimilarity; Function unclear YP_692900.1 metalloprotease YP_692901.1 identified by match to PFAM protein family HMMPF03602 YP_692903.1 broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor YP_692904.1 identified by match to PFAM protein family HMMPF03352 YP_692905.1 identified by match to PFAM protein family HMMPF03675 InterPro: Cytochrome c class I; Family membership YP_692906.1 identified by sequence similarity; InterPro: CorA-like Mg2+ transporter protein; Family membership YP_692907.1 identified by Glimmer2 YP_692908.1 (sulphite reductase hemoprotein beta subunit) identified by sequence similarity; InterPro: Nitrite and sulfite reductase; High confidence in function and specificity YP_692910.1 yhgI protein identified by sequence similarity; InterPro: Hypothetical hesB/yadR/yfhF family YP_692911.1 identified by match to PFAM protein family HMMPF01435 YP_692912.1 (ABC1 family protein, ubiquinone biosynthesis protein) identified by sequence similarity; InterPro: ABC1 family; Family membership YP_692913.1 (SET domain protein lysine methyltransferase, ) InterPro: SET-domain of transcriptional regulators (TRX EZ ASH1 etc); Family membership YP_692914.1 (pseudouridylate synthase)(uracil hydrolyase).; High confidence in function and specificity YP_692915.1 identified by match to PFAM protein family HMMPF00004 InterPro: ATP-dependent protease La; High confidence in function and specificity YP_692916.1 identified by sequence similarity. InterPro: SAM (and some other nucleotide) binding motif YP_692917.1 Carboxylic ester hydrolases identified by sequencesimilarity; InterPro: Alpha/beta hydrolase fold; Family membership YP_692918.1 membrane protein identified by match to PFAM protein family HMMPF00892 InterPro: Integral membrane protein DUF6; Function unclear YP_692919.1 (2-5 RNA ligase ) identified by sequence similarity YP_692920.1 (conserved hypothetical protein TIGR00481) identified by sequence similarity. YP_692921.1 catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate YP_692922.1 (lipid A biosynthesis lauroyl acyltransferase; ) identified by sequence similarity; High confidence in function and specificity YP_692923.1 identified by sequence similarity; High confidence in function and specificity YP_692924.1 Family membership YP_692925.1 (ppiB) (peptidyl-prolyl cis-trans isomerase A,precursor) identified by match to PFAM protein family HMMPF00160 InterPro: Cyclophilin-type peptidyl-prolyl cis-trans isomerase; High confidence in function and specificity YP_692926.1 (peptidyl-prolyl cis-trans isomerase B) identified by match to PFAM protein family HMMPF00160 InterPro: Cyclophilin-type peptidyl-prolyl cis-trans isomerase; High confidence in function and specificity YP_692927.1 catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_692928.1 (5, 10-methylenetetrahydromethanopterin cyclohydrolase) identified by match to PFAM protein family HMMPF00763 InterPro: Tetrahydrofolate dehydrogenase/cyclohydrolase; High confidence in function and specificity YP_692929.1 (trigger factor) identified by sequence similarity; InterPro: FKBP-type peptidyl-prolyl cis-trans isomerase (PPIase); High confidence in function and specificity YP_692930.1 identified by sequencesimilarity; InterPro: Clp protease; Hypothetical protein YP_692931.1 binds and unfolds substrates as part of the ClpXP protease YP_692932.1 (lon-2) identified by match to PFAM protein family HMMPF00004 InterPro: ATP-dependent protease La; High confidence in function and specificity YP_692933.1 DNA-binding protein HU 1 (DNA-binding protein II) (HB); Specificity unclear YP_692934.1 peptidyl-prolyl isomerase identified by sequence similarity; InterPro: PpiC-type peptidyl-prolyl cis-trans isomerase; High confidence in function and specificity YP_692935.1 identified by sequence similarity; InterPro: Short-chain dehydrogenase/reductase (SDR) superfamily; High confidence in function and specificity YP_692936.1 (oligopeptide ABC transporter, ATP-binding protein) identified ba sequence similarity and by match to PFAM protein family HMMPF00005; InterPro: AAA ATPase superfamily; High confidence in function and specificity YP_692937.1 (oligopeptide ABC transporter, permease protein) identified by sequence similarity and by match to PFAM protein family HMMPF00528; InterPro: Binding-protein-dependent transport systems inner membrane component; High confidence in function and specificity YP_692938.1 (oligopeptide ABC transporter, permease protein) identified by sequence similarity and by match to PFAM protein family HMMPF00528; InterPro: Binding-protein-dependent transport systems inner membrane component; High confidence in function and specificity YP_692939.1 (oligopeptide ABC transporter periplasmic peptide-binding protein ) identified by sequence similarity and by match to PFAM protein family HMMPF00496; InterPro: Bacterial extracellular solute-binding protein family 5; Function unclear YP_692940.1 (oligopeptide ABC transporter periplasmic peptide-binding protein ) identified by sequence similarity and by match to PFAM protein family HMMPF00496; InterPro: Bacterial extracellular solute-binding protein family 5; Function unclear YP_692941.1 identified by match to PFAM protein family HMMPF01464 InterPro: SLT domain; High confidence in function and specificity YP_692942.1 (Metallo-beta-lactamase family protein, including beta-lactamase, hiolesterases, members of the glyoxalase II family, ) identified by sequence similarity; InterPro: Metallo-beta-lactamase superfamily; Family membership YP_692943.1 conserved hypothetical protein identified by sequencesimilarity YP_692944.1 (ribonuclease HI) identified by sequence similarity; InterPro: RNase H; High confidence in function and specificity YP_692945.1 identified by sequence similarity; InterPro: Exonuclease; High confidence in function and specificity YP_692946.1 involved in regulation of intracellular pH under alkaline conditions YP_692948.1 identified by sequence similarity; InterPro: NUDIX hydrolase; Specificity unclear YP_692950.1 SohB; periplasmic protein; member of the peptidase S49 family YP_692951.1 (alcohol dehydrogenase, ) identified by sequencesimilarity; InterPro: Zinc-containing alcohol dehydrogenase superfamily; Family membership YP_692952.1 identified by sequence similarity; Family membership YP_692953.1 identified by sequencesimilarity; High confidence in function and specificity YP_692954.1 identified by sequence similarity; InterPro: DnaJ N-terminal domain; Specificity unclear YP_692956.1 AcsA; in Sinorhizobium meliloti this enzyme is required for acetoacetate activation; similar to acetyl-CoA synthase YP_692957.1 identified by match to TIGR protein family HMMTIGR00514 InterPro: Carbamoyl-phosphate synthase; High confidence in function and specificity YP_692958.1 identified by match to PFAM protein family HMMPF00378, InterPro: Enoyl-CoA hydratase/isomerase; High confidence in function and specificity YP_692959.1 (Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta), ) identified by sequencesimilarity; InterPro: Carboxyl transferase family; High confidence in function and specificity YP_692960.1 identified by sequencesimilarity; InterPro: Acyl-CoA dehydrogenase; High confidence in function and specificity YP_692961.1 transcriptional regulator, InterPro: Bacterial regulatory proteins MerR family; Hypothetical protein YP_692962.1 (membrane protein, ) identified by sequence similarity; InterPro: HMGCR/Patched 5TM box; Function unclear YP_692963.1 sensor histidine kinase containing HisKA, HATPase_c and Response_reg domains, identified by match to PFAM protein family HMMPF04171 InterPro: Histidine kinase C-terminal; Conserved hypothetical protein YP_692964.1 identified by match to PFAM protein family HMMPF01118 YP_692965.1 regulator of RNase E; increases half-life and abundance of RNAs; interacts with RNase E possibly inhibiting catalytic activity YP_692966.1 (CBS domain protein, ) identified by sequence similarity; InterPro: CBS domain; Function unclear YP_692967.1 (ftsK) identified by sequence similarity; Hypothetical protein YP_692968.1 catalyzes the oxidation of malate to oxaloacetate YP_692969.1 Hypothetical protein YP_692970.1 ranscriptional regulator AraC family identified by match to PFAM protein family HMMPF00165 InterPro: AraC type helix-turn-helix; Family membership YP_692971.1 InterPro: Carboxylesterases type-B; High confidence in function and specificity YP_692972.1 identified by sequence similarity; InterPro: BolA-like protein; High confidence in function and specificity YP_692973.1 (conserved hypothetical protein containing rhodanese-like domain) identified by match to PFAM protein family HMMPF00581 InterPro: Rhodanese/cdc25 fold YP_692974.1 (molybdate ABC transporter periplasmic molybdate-binding protein) identified by match to TIGR protein family HMMTIGR01256; Family membership YP_692975.1 identified by sequence similarity; InterPro: Binding-protein-dependent transport systems inner membrane component; Family membership YP_692976.1 identified by sequencesimilarity; InterPro: AAA ATPase superfamily; Family membership YP_692979.1 identified by sequence similarity; InterPro: Cholesterol oxidase (CHOD); Function unclear YP_692981.1 identified by match to PFAM protein family HMMPF03695 YP_692982.1 GGDEF domain protein identified by match to PFAM protein family HMMPF00990 InterPro: Domain of unknown function DUF9; Function unclear YP_692983.1 oxidoreductase (acting on the CH-CH group) identified by sequencesimilarity; InterPro: Acyl-CoA dehydrogenase; Family membership YP_692984.1 (acdA) identified by sequencesimilarity; InterPro: Acyl-CoA dehydrogenase; Specificity unclear YP_692985.1 oxidoreductase (acting on the CH-OH group of donors) InterPro: Short-chain dehydrogenase/reductase (SDR) superfamily; Family membership YP_692986.1 identified by sequencesimilarity; InterPro: Uncharacterized protein family UPF0021 YP_692987.1 catalyzes the formation of malate from glyoxylate and acetyl-CoA YP_692989.1 identified by match to PFAM protein family HMMPF02390 InterPro: SAM (and some other nucleotide) binding motif; Hypothetical protein YP_692991.1 acetyltransferase (transferring groups other than amino-acyl groups) identified by match to PFAM protein family HMMPF00583 InterPro: GCN5-related N-acetyltransferase; Family membership YP_692993.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide YP_692994.1 HflD; UPF0274; in Escherichia coli this protein is peripherally associated with the membrane and appears to act with lambda CII protein; in Haemophilus influenzae a knockout of the HI0638 gene affected paracytosis YP_692995.1 (tRNA(5-methylaminomethyl-2-thiouridylate)-methyltr ansferase) identified by sequencesimilarity; InterPro: tRNA methyl transferase tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase catalyses the addition of 5-methylaminomethyl-2-thiouridylate to tRNAs using S-adenosyl-L-methionine as a substrate and releasing S-adenosyl-L-homocysteine. The enzyme is cytoplasmic and is involved in tRNA processing.; High confidence in function and specificity YP_692996.1 Region start changed from 1451926 to 1451869 (-57 bases) YP_692997.1 identified by match to TIGR protein family HMMTIGR00581 InterPro: MoaC family; High confidence in function and specificity YP_692998.1 identified by sequence similarity; High confidence in function and specificity YP_692999.1 identified by sequencesimilarity; InterPro: Molydopterin converting factor subunit 2; High confidence in function and specificity YP_693000.1 (RNA pseudouridylate synthase, pseudouridine synthase; Ribosomal large subunit pseudouridine synthase E). Similar to PA3968 - Pseudomonas aeruginosa (strain PAO1) Pfam: PseudoU_synth_2; RNA pseudouridylate synthase; Family membership YP_693001.1 (isocitrate dehydrogenase NADP-dependent monomeric-type) identified by match to PFAM protein family HMMPF03971 InterPro: Isocitrate dehydrogenase NADP-dependent monomeric type; High confidence in function and specificity YP_693002.1 (icd) (isocitrate dehydrogenase NADP-dependentprokaryotic-type) identified by match to TIGR protein family HMMTIGR00183 InterPro: Isocitrate dehydrogenase NADP-dependent prok type; High confidence in function and specificity YP_693003.1 Region start changed from 1458024 to 1458129 (105 bases) YP_693004.1 identified by match to PFAM protein family HMMPF02617 YP_693005.1 identified by sequencesimilarity; InterPro: AAA-protein (ATPases associated with various cellular activities); High confidence in function and specificity YP_693006.1 identified by sequencesimilarity; InterPro: S1 RNA binding domain; High confidence in function and specificity YP_693007.1 Conjugates Arg from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate YP_693008.1 leucyltransferase; phenylalanyltransferse; functions in the N-end rule pathway; transfers Leu, Phe, Met, from aminoacyl-tRNAs to N-terminal of proteins with Arg or Lys YP_693009.1 (thioredoxin reductase; NADP-thioredoxin reductase) identified by sequencesimilarity; InterPro: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; High confidence in function and specificity YP_693010.1 identified by sequence similarity; InterPro: FtsK/SpoIIIE family This domain contains a ATP binding P-loop motif. It is found in the FtsK cell division protein from E. coli FTSK_ECOLI and the stage III sporulation protein E SpoIIIE; Family membership YP_693011.1 identified by sequencesimilarity; InterPro: Outer membrane lipoprotein carrier protein LolA; High confidence in function and specificity YP_693012.1 (ATPase AAA family) identified by sequencesimilarity; InterPro: AAA-protein (ATPases associated with various cellular activities); Conserved hypothetical protein YP_693013.1 identified by sequencesimilarity; InterPro: CRCB protein; Family membership YP_693014.1 identified by match to TIGR protein family HMMTIGR00414 InterPro: Seryl-tRNA synthetase; High confidence in function and specificity YP_693015.1 identified by sequencesimilarity; InterPro: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; High confidence in function and specificity YP_693016.1 identified by sequence similarity; identified by match to PFAM protein family HMMPF02885; InterPro: Glycosyl transferase family; Family membership YP_693019.1 DsrE, Uncharacterized conserved protein involved in intracellular sulfur reduction, identified by sequences imilarity InterPro: DsrE-like protein; Family membership YP_693020.1 identified by match to PFAM protein family HMMPF04178 InterPro: Uncharacterized protein family UPF0005 YP_693021.1 arsenical pump-driving ATPase (Arsenite-translocating ATPase) (Arsenical resistance ATPase) (Arsenite-transporting ATPase) InterPro: Anion-transporting ATPase; Specificity unclear YP_693023.1 identified by sequencesimilarity; InterPro: Carbon starvation protein CstA; High confidence in function and specificity YP_693024.1 identified by sequence similarity; InterPro: Response regulator receiver domain; Specificity unclear YP_693025.1 identified by match to TIGR protein family HMMTIGR00194; High confidence in function and specificity YP_693026.1 (CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase) identified by sequencesimilarity; InterPro: CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase; High confidence in function and specificity YP_693027.1 sensor histidine kinase/respose regulator, contains HisKA, HATPase_c and two Response_reg receiver domains; identified by sequencesimilarity; InterPro: Histidine kinase C-terminal; Family membership YP_693028.1 (chemotaxis protein methyltransferase CheR-like) identified by sequence similarity; InterPro: CheR-type MCP methyl-transferase; High confidence in function and specificity YP_693029.1 identified by sequencesimilarity; InterPro: Response regulator receiver domain; High confidence in function and specificity YP_693030.1 identified by sequencesimilarity; InterPro: CheB methylesterase; High confidence in function and specificity YP_693031.1 sensory box protein/response regulator identified by sequencesimilarity; Function unclear YP_693032.1 Involved in a general secretion pathway (GSP) for the export of proteins. Belongs to the GSP E family,identified by sequence similarity. InterPro: Bacterial type II secretion system protein E; Family membership YP_693033.1 Involved in a general secretion pathway (GSP) for the export of proteins. Belongs to the GSP F family,identified by sequence similarity. InterPro: Bacterial type II secretion system protein; Family membership YP_693034.1 Involved in a general secretion pathway (GSP) for the export of proteins. Required for the translocation of a variety of enzymes across the outer membrane.Belongs to the GSP G family.; Family membership YP_693035.1 Involved in a general secretion pathway (GSP) for the export of proteins. Belongs to the GSP H family, by sequence similarity.; Family membership YP_693036.1 Involved in a general secretion pathway (GSP) for the export of proteins. Belongs to the GSP I family,identified by sequence similarity InterPro: Bacterial type II secretion system protein I/J; Family membership YP_693037.1 Involved in a general secretion pathway (GSP) for the export of proteins. Belongs to the GSP J family,identified by sequence similarity; Family membership YP_693038.1 Involved in a general secretion pathway (GSP) for the export of proteins. Required for the translocation of the multiple pectic enzymes. Belongs to the GSP K family,identified by sequence similarity; Family membership YP_693039.1 Involved in a general secretion pathway (GSP) for the export of proteins. Belongs to the GSP L family,identified by sequence similarity.; Family membership YP_693040.1 Involved in a general secretion pathway (GSP) for the export of proteins. Belongs to the GSP M family,identified by sequence similarity.; Family membership YP_693042.1 conserved hypothetical protein, with pyruvate phosphate dikinase domain, PPDK_N YP_693043.1 Function unclear YP_693044.1 one of two methionine synthases in Escherichia coli; MetH catalyzes a methyl transfer reaction from methyltetrahydrofolate to homocysteine to create methionine; requires zinc for activity YP_693045.1 (conserved hypothetical protein) identified by match to PFAM protein family HMMPF00924 InterPro: Uncharacterized protein family UPF0003; High confidence in function and specificity YP_693046.1 (conserved hypothetical protein) identified by sequence similarity YP_693047.1 (pyridine nucleotide transhydrogenase betasubunit) identified by sequence similarity; InterPro: NAD(P) transhydrogenase beta subunit; High confidence in function and specificity YP_693048.1 ocidoredutase (acting on NADH or NADPH with NAD+ or NADP+ as acceptor); Family membership YP_693049.1 (transcriptional regulator LysR family) identified by match to PFAM protein family HMMPF03466 InterPro: Alanine dehydrogenase and pyridine nucleotide transhydrogenase; High confidence in function and specificity YP_693050.1 Region start changed from 1511994 to 1511937 (-57 bases) YP_693051.1 hydrolase alpha/beta fold family identified by match to TIGR protein family HMMTIGR01738 InterPro: Alpha/beta hydrolase fold; Family membership YP_693052.1 (tail-specific protease prc) identified by sequence similarity; InterPro: Carboxyl-terminal protease; High confidence in function and specificity YP_693053.1 Hypothetical protein YP_693054.1 conserved hypothetical protein with some similarity to AlkB, DNA repair system specific for alkylated DNA YP_693055.1 identified by match to TIGR protein family HMMTIGR00383 InterPro: CorA-like Mg2+ transporter protein; Family membership YP_693056.1 identified by match to PFAM protein family HMMPF00753 InterPro: Metallo-beta-lactamase superfamily; Family membership YP_693058.1 identified by match to PFAM protein family HMMPF03883 YP_693060.1 identified by sequencesimilarity; InterPro: Universal stress protein (Usp); Specificity unclear YP_693061.1 identified by sequencesimilarity; InterPro: Cyclic nucleotide-binding domain; Specificity unclear YP_693062.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III YP_693064.1 InterPro: Cytochrome oxidase maturation protein cbb3-type; Function unclear YP_693065.1 cation-transporting P-type ATPase identified by sequence similarity; InterPro: E1-E2 ATPases; Hypothetical protein YP_693067.1 identified by match to PFAM protein family HMMPF00037 InterPro: 4Fe-4S ferredoxin iron-sulfur binding domain; High confidence in function and specificity YP_693068.1 (cytochrome c oxidase cbb3-type subunit III) identified by match to TIGR protein family HMMTIGR00782 InterPro: Cytochrome c oxidase cbb3-type subunit III; High confidence in function and specificity YP_693069.1 (cytochrome c oxidase cbb3-type CcoQ subunit) identified by sequence similarity; Family membership YP_693070.1 identified by match to TIGR protein family HMMTIGR00781 InterPro: Cytochrome C oxidase mono-heme subunit/FixO; Family membership YP_693071.1 identified by match to TIGR protein family HMMTIGR00780 InterPro: Cytochrome c oxidase cbb3-type subunit I; High confidence in function and specificity YP_693072.1 identified by sequencesimilarity; InterPro: Zinc-containing alcohol dehydrogenase superfamily; Family membership YP_693073.1 identified by sequencesimilarity; InterPro: Bacterial regulatory protein LysR family; Family membership YP_693074.1 (Transposon protein A, transposition regulatory protein tnpA homolog - Sphingomonas aromaticivorans plasmid pNL1, ) InterPro: Phage integrase; High confidence in function and specificity YP_693075.1 (transponson protein B homolog - Sphingomonas aromaticivorans plasmid pNL1) InterPro: Phage integrase; Family membership YP_693076.1 identified by sequencesimilarity; InterPro: Heavy metal efflux pump CzcA; High confidence in function and specificity YP_693077.1 heavy metal RND efflux membrane fusion protein CzcB family identified by sequence similarity; Family membership YP_693078.1 identified by sequencesimilarity; Family membership YP_693080.1 copper/heavy metal-translocating P-type ATPase) identified by sequencesimilarity; InterPro: Haloacid dehalogenase/epoxide hydrolase family; High confidence in function and specificity YP_693081.1 identified by match to TIGRFAM protein family HMMTIGR00911; InterPro: Amino acid permease; Family membership YP_693082.1 (copper resistance protein B); Conserved hypothetical protein YP_693083.1 (copper resistance protein CopA family) identified by sequencesimilarity; InterPro: Multicopper oxidase type 1; High confidence in function and specificity YP_693084.1 copper-binding protein plastocyanin/azurin family identified by match to PFAM protein family HMMPF00127; Specificity unclear YP_693085.1 identified by match to TIGR protein family HMMTIGR01387 InterPro: Response regulator receiver domain; Specificity unclear YP_693086.1 identified by match to PFAM protein family HMMPF02518 InterPro: Histidine kinase C-terminal; Family membership YP_693087.1 transcriptional regulator MerR family identified by match to PFAM protein family HMMPF00376 InterPro: Bacterial regulatory proteins MerR family; Family membership YP_693088.1 (Cation efflux system permease, ),identified by sequence similarity; InterPro: Heavy-metal-associated domain; High confidence in function and specificity YP_693089.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis YP_693090.1 (transcriptional regulator, ) identified by match to PFAM protein family HMMPF01381 InterPro: Helix-turn-helix motif; Family membership YP_693091.1 conserved hypothetical protein, Predicted metal-binding protein related to the C-terminal domain of SecA;,identified by match to PFAM protein family HMMPF02810 InterPro: SEC-C motif; Family membership YP_693092.1 Family membership YP_693093.1 InterPro: Uncharacterized protein family UPF0060 Uncharacterized BCR, YnfA/UPF0060 family This entry describes integral membrane proteins of unknown function. YP_693094.1 (cobalt/cadmium/zinc transporter CDF family),identified by sequencesimilarity; InterPro: Cation efflux family; Family membership YP_693096.1 conserved hypothetical protein YP_693097.1 (CzcA) cobalt/zinc/cadmium efflux RND transporterpermease protein (CzcA family) identified by match to PFAM protein family HMMPF04295 InterPro: Heavy metal efflux pump CzcA; Family membership YP_693098.1 heavy metal RND efflux membrane fusion protein (CzcB family) identified by sequence similarity; Family membership YP_693099.1 cobalt/zinc/cadmium efflux RND transporter outermembrane protein (CzcC family) identified by sequencesimilarity; InterPro: Outer membrane efflux protein; Family membership YP_693100.1 (hydrolase, alpha/beta fold protein family, ) identify by sequence similarity and Pfam; InterPro: Alpha/beta hydrolase fold; Family membership YP_693101.1 (cobalt/zinc/cadmium efflux RND transporter outermembrane protein CzcC family) identified by sequencesimilarity; InterPro: Outer membrane efflux protein; Conserved hypothetical protein YP_693102.1 (heavy metal RND efflux membrane fusion protein,CzcB family) identified by sequence similarity; Family membership YP_693103.1 (cobalt/zinc/cadmium efflux RND transporterpermease protein CzcA family) identified by match to PFAM protein family HMMPF04295 InterPro: Heavy metal efflux pump CzcA; Family membership YP_693104.1 identified by Glimmer2 YP_693105.1 (ATPase, AAA family protein, ) identified by match to PFAM protein family HMMPF00004; Family membership YP_693106.1 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase YP_693107.1 identified by match to PFAM protein family HMMPF01479 InterPro: Conserved hypothetical protein 93 YP_693108.1 (conserved hypothetical protein TIGR00281) identified by match to PFAM protein family HMMPF04079 YP_693109.1 identified by match to PFAM protein family HMMPF02616 InterPro: DUF173 YP_693110.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_693111.1 Sua5/YciO/YrdC/YwlC family protein) identified by match to TIGR protein family HMMTIGR00057 InterPro: Sua5/YciO/YrdC/YwlC protein family; Family membership YP_693112.1 (Polymerase and Histidinol Phosphatase, PHP domain N-terminal region:PHP domain C-terminal region, ) identified by match to PFAM protein family HMMPF02231; Family membership YP_693113.1 Family membership YP_693114.1 unknown function; YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the predicted reactions based on sequence and structure similarity YP_693115.1 (conserved hypothetical protein; SH3 domain protein) identified by sequencesimilarity YP_693117.1 identified by match to TIGR protein family HMMTIGR00530, InterPro: Phospholipid and glycerol acyltransferase (from motifs_6.msf); Family membership YP_693120.1 (GDSL lipase/acylhydrolase family protein) identified by match to PFAM protein family HMMPF00657; InterPro: GDSL lipolytic enzyme; High confidence in function and specificity YP_693121.1 polyamine ABC transporter ATP-binding protein identified by match to TIGR protein family HMMTIGR01187 InterPro: AAA ATPase superfamily; Family membership YP_693122.1 ABC transporter permease protein identified by sequencesimilarity; Specificity unclear YP_693123.1 (multidrug resistance transporter Bcr/CflAfamily) identified by match to TIGR protein family HMMTIGR00880; InterPro: Drug resistance transporter Bcr/CflA subfamily; Family membership YP_693124.1 identified by match to PFAM protein family HMMPF04290 InterPro: Na+/H+ exchanger; Family membership YP_693125.1 identified by match to PFAM protein family HMMPF00376 InterPro: Bacterial regulatory proteins MerR family; Family membership YP_693127.1 (sugar kinase) identified by sequence similarity; InterPro: Carbohydrate kinase FGGY family; Family membership YP_693128.1 identified by match to PFAM protein family HMMPF01266 InterPro: D-amino acid oxidase; High confidence in function and specificity YP_693129.1 InterPro: FAD linked oxidase C-terminal; Function unclear YP_693130.1 (Acyltransferase family protein) identified by sequencesimilarity; InterPro: Phospholipid and glycerol acyltransferase (from motifs_6.msf); Family membership YP_693131.1 identified by match to PFAM protein family HMMPF00691 InterPro: Bacterial outer membrane protein; Family membership YP_693132.1 (adaptive response regulator protein) identified by match to PFAM protein family HMMPF01035 InterPro: Methylated-DNA--protein-cysteine methyltransferase AraC type helix-turn-helix; High confidence in function and specificity YP_693134.1 transporter identified by match to PFAM protein family HMMPF03600; Specificity unclear YP_693135.1 (hypothetical protein) identified by sequencesimilarity YP_693136.1 conserved hypothetical protein YP_693137.1 Uncharacterized protein, possibly involved in aromatic compounds catabolism (translation initiation factor, probable) identified by match to TIGR protein family HMMTIGR00369 YP_693138.1 Alpha/beta hydrolase fold, PHA_synth_III_C: poly(R)-hydroxyalkanoic acid synthase, class III, PhaC subunit; High confidence in function and specificity YP_693140.1 Conserved hypothetical protein YP_693142.1 identified by match to PFAM protein family HMMPF00991 InterPro: ParA family ATPase; Family membership YP_693143.1 identified by sequencesimilarity; InterPro: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; High confidence in function and specificity YP_693144.1 identified by sequence similarity; identified by match to PFAM protein family HMMPF01645 InterPro: Ferredoxin-dependent glutamate synthase; Function unclear YP_693145.1 identified by sequencesimilarity; InterPro: SLT domain; High confidence in function and specificity YP_693146.1 Family membership YP_693147.1 catalyzes the formation of phosphoenolpyruvate from pyruvate YP_693148.1 identified by sequencesimilarity YP_693149.1 functions in propionate metabolism; involved in isomerization of (2S,3S)-methylcitrate to (2R,3S)-methylisocitrate; also encodes minor aconitase or dehydratase activity; aconitase C YP_693150.1 identified by match to PFAM protein family HMMPF04303 YP_693151.1 Catalyzes the conversion of citrate to isocitrate YP_693152.1 methylcitrate synthase identified by sequence similarity; InterPro: Citrate synthase; High confidence in function and specificity YP_693153.1 catalyzes the formation of pyruvate and succinate from 2-methylisocitrate YP_693154.1 identified by match to PFAM protein family HMMPF00392 InterPro: Bacterial regulatory proteins GntR family; Family membership YP_693155.1 (para-aminobenzoate synthase component I, ) identified by sequence similarity; identified by match to PFAM protein family HMMPF00425 and match to TIGRFAM protein family HMMTIGR00553 InterPro: Anthranilate synthase component I and chorismate binding enzyme; Function unclear YP_693156.1 catalyzes the formation of serine from phosphoserine; also has phosphoserine:homoserine phosphotransferase activity YP_693157.1 LysR-type transcriptional regulator; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates cysteine biosynthesis by controlling expression of the cys regulon; autoregulates expression; crystal structure of Klebsiella aerogenes showed tetramer formation YP_693158.1 5-nucleotidase identified by sequencesimilarity; Conserved hypothetical protein YP_693162.1 Conserved hypothetical protein YP_693164.1 initiation factor 2 subunit family; High confidence in function and specificity YP_693165.1 ( sugar aldolase) identified by match to TIGR protein family HMMTIGR01086, Family membership YP_693166.1 InterPro: Acireductone dioxygenase (ARD and ARD); Family membership YP_693167.1 identified by sequencesimilarity; InterPro: Haloacid dehalogenase/epoxide hydrolase family; Family membership YP_693168.1 (rmsC) identify by sequence similarity.; Family membership YP_693169.1 identified by sequencesimilarity; InterPro: DEAD/DEAH box helicase; High confidence in function and specificity YP_693171.1 identified by match to PFAM protein family HMMPF01841; Family membership YP_693172.1 identified by match to PFAM protein family HMMPF01882 InterPro: Protein of unknown function DUF58 YP_693173.1 (ATPase, AAA protein family, ) identified by match to PFAM protein family HMMPF00004; Family membership YP_693174.1 identified by sequence similarity; identified by match to PFAM protein family HMMPF01053; InterPro: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes; High confidence in function and specificity YP_693175.1 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway YP_693176.1 identified by sequence similarity; InterPro: Colicin V production protein; Family membership YP_693177.1 identified by Glimmer2; Function unclear YP_693178.1 identified by sequence similarity; InterPro: Cytoplasmic peptidoglycan synthetases N-terminal; High confidence in function and specificity YP_693179.1 (acetyl-CoA carboxylase carboxyl transferase beta subunit) identified by match to PFAM protein family HMMPF04067 InterPro: Acetyl-CoA carboxylase carboxyl transferase beta subunit; High confidence in function and specificity YP_693180.1 catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis YP_693181.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate YP_693182.1 identified by sequence similarity; identified by match to PFAM protein family HMMPF00697 InterPro: N-(5phosphoribosyl)anthranilate isomerase (PRAI); High confidence in function and specificity YP_693183.1 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability YP_693184.1 identified by sequence similarity YP_693185.1 identified by sequence similarity; identified by match to PFAM protein families HMMPF01118 and HMMPF02774 InterPro: Semialdehyde dehydrogenase; High confidence in function and specificity YP_693186.1 catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde YP_693187.1 (3-isopropylmalate dehydrogenase, beta-ipm dehydrogenase) identified by sequence similarity; identified by match to PFAM protein family HMMPF00180 and TIGRFAM protein family HMMTIGR00169 InterPro: Isocitrate and isopropylmalate dehydrogenases 3-isopropylmalate dehydrogenase; High confidence in function and specificity YP_693188.1 Function unclear YP_693189.1 (3-isopropylmalate dehydratase small subunit,isopropylmalate isomerase, alpha-ipm isomerase) identified by sequence similarity; identified by match to TIGRFAM protein family HMMTIGR00171 InterPro: 3-isopropylmalate dehydratase small subunit; High confidence in function and specificity YP_693190.1 dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate YP_693191.1 identified by match to PFAM protein family HMMPF03466 InterPro: Bacterial regulatory protein LysR family; Family membership YP_693192.1 conserved hypothetical protein, probable MFS metabolite transporter, hypothetical transport protein ywbf.; Family membership YP_693193.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis YP_693194.1 involved in methylation of ribosomal protein L3 YP_693196.1 identified by match to PFAM protein family HMMPF00909 InterPro: Ammonium transporter family; High confidence in function and specificity YP_693198.1 (proton/sodium-glutamate/aspartate symporter) identified by match to PFAM protein family HMMPF03600 InterPro: Sodium:dicarboxylate symporter family; Family membership YP_693199.1 oxidoreductase short chaindehydrogenase/reductase family identified by match to TIGR protein family HMMTIGR01500 InterPro: Short-chain dehydrogenase/reductase (SDR) superfamily; Family membership YP_693201.1 identified by match to PFAM protein family HMMPF00990 InterPro: Domain of unknown function DUF9; Family membership YP_693202.1 identified by match to PFAM protein family HMMPF01575 InterPro: MaoC-like dehydratase domain; Family membership YP_693203.1 hydrolase (acting on ester bonds) identified by match to TIGR protein family HMMTIGR01738 InterPro: Alpha/beta hydrolase fold; Family membership YP_693204.1 identified by match to TIGR protein family HMMTIGR01738; Family membership YP_693205.1 (xth) , (Exonuclease III),(EXO III),(APendonuclease VI). identified by sequencesimilarity; InterPro: AP endonucleases family 1 Exodeoxyribonuclease III xth; High confidence in function and specificity YP_693207.1 identified by match to TIGR protein family HMMTIGR00249 InterPro: Phosphohistidine phosphatase SixA; High confidence in function and specificity YP_693208.1 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate YP_693209.1 molecular chaperone YP_693212.1 identified by sequencesimilarity; InterPro: ATP-citrate lyase/succinyl-CoA ligases catalytic activity: atp + succinate + coa = adp + succinyl-coa + phosphate; High confidence in function and specificity YP_693213.1 identified by sequence similarity; InterPro: ATP-grasp domain catalytic activity: atp + succinate + coa = adp + succinyl-coa + phosphate; High confidence in function and specificity YP_693214.1 (2-oxoglutarate dehydrogenase lipoamidedehydrogenase component) identified by sequence similarity; catalytic activity: dihydrolipoamide + nad(+) = lipoamide + nadh; High confidence in function and specificity YP_693215.1 (dihydrolipoamidesuccinyltransferase) identified by sequence similarity; InterPro: 2-Oxo acid dehydrogenase acyltransferase catalytic domain catalytic activity: succinyl-coa + dihydrolipoamide = coa + s-succinyldihydrolipoamide the e2 component contains one covalently-bound lipoyl cofactor; High confidence in function and specificity YP_693216.1 SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide YP_693217.1 (succinate dehydrogenase iron-sulfur protein) identified by match to TIGR protein family HMMTIGR00384 InterPro: Succinate dehydrogenase/fumarate reductase iron-sulfur protein catalytic activity: succinate + ubiquinone = fumarate + ubiquinol; High confidence in function and specificity YP_693218.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol YP_693219.1 (succinate dehydrogenase hydrophobic membraneanchor protein) identified by sequence similarity; part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur, cytochrome b-556, and an hydrophobic anchor protein.; Function unclear YP_693220.1 identified by sequence similarity; part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur, cytochrome b-556, and an hydrophobic anchor protein; High confidence in function and specificity YP_693221.1 type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH YP_693222.1 identifiedby sequence similarity; InterPro: Strictosidine synthase YP_693223.1 identified by sequencesimilarity; Family membership YP_693224.1 (conserved hypothetical protein,; Family membership YP_693225.1 identified by sequence similarity YP_693227.1 Ferrichrome-iron receptor precursor (Ferric hydroxamate uptake) (Ferric hydroxamate receptor)., TonB-dependent siderophore receptor, TonB-dependent Receptor Plug Domain, TonB-siderophor: TonB-dependent siderophore receptor; High confidence in function and specificity YP_693228.1 (membrane protein ) identified by sequence similarity; Family membership YP_693229.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation YP_693231.1 identified by match to PFAM protein family HMMPF00582 InterPro: Universal stress protein (Usp); Family membership YP_693232.1 identified by match to PFAM protein family HMMPF04235 InterPro: Sulfate transporter; Family membership YP_693233.1 identified by match to PFAM protein family HMMPF01207 InterPro: TIM-barrel protein yjbN family; Family membership YP_693234.1 identified by sequence similarity; InterPro: Transaldolase; Family membership YP_693236.1 (vacJ) (vacJ lipoprotein) VacJis attached to the outer membrane by a lipid anchor (by similarity); Function unclear YP_693240.1 catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs YP_693241.1 identified by sequence similarity; InterPro: DEAD/DEAH box helicase; Family membership YP_693242.1 Family membership YP_693243.1 (hydrolase alpha/beta fold family, ) identified by match to TIGR protein family HMMTIGR01738 InterPro: Esterase/lipase/thioesterase family active site; Family membership YP_693245.1 identified by sequencesimilarity; InterPro: Bacterial extracellular solute-binding proteins family 3; Family membership YP_693247.1 InterPro: Bacterial outer membrane protein; Family membership YP_693248.1 Hypothetical protein YP_693249.1 (CAIB/BAIF family protein; CoA-transferase family protein) identified by match to PFAM protein family HMMPF02515 InterPro: CAIB/BAIF family; Family membership YP_693250.1 (peptide methionine sulfoxide reductase) identified by match to PFAM protein family HMMPF01625 InterPro: Peptide methionine sulfoxide reductase; High confidence in function and specificity YP_693251.1 this stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress YP_693252.1 (conserved hypothetical protein) identified by sequencesimilarity YP_693253.1 transcriptional regulator AraC family identified by match to PFAM protein family HMMPF00165; Function unclear YP_693255.1 (transport protein, ) identified by sequencesimilarity; InterPro: HMGCR/Patched 5TM box; Family membership YP_693257.1 identified by match to TIGR protein family HMMTIGR01668 InterPro: Haloacid dehalogenase/epoxide hydrolase family; Family membership YP_693258.1 ( YP_693259.1 High confidence in function and specificity YP_693260.1 (fumarate hydratase class I) identified by sequence similarity; InterPro: Fe-S type hydro-lyases tartrate/fumarate alpha region; High confidence in function and specificity YP_693261.1 hydrolase alpha/beta fold family identified by match to TIGR protein family HMMTIGR01738 InterPro: Alpha/beta hydrolase fold; Family membership YP_693262.1 hydrolase (acting on acid anhydrides in phosphorus-containing anhydrides) by match to PFAM protein family HMMPF03475 InterPro: Acylphosphatase; Family membership YP_693263.1 (ribonuclease BN ) identified by match to PFAM protein family HMMPF03631; paralog of Abo_259 InterPro: Ribonuclease BN; Family membership YP_693264.1 identified by sequence similarity; Family membership YP_693265.1 identified by sequence similarity; InterPro: Flavodoxin; Family membership YP_693271.1 (ATPase, AAA protein family, ) identified by match to PFAM protein family HMMPF00004 InterPro: AAA ATPase superfamily; Family membership YP_693272.1 identified by match to PFAM protein family HMMPF01882 InterPro: Protein of unknown function DUF58 YP_693273.1 Function unclear YP_693274.1 (MATE efflux family protein, ) identified by match to PFAM protein family HMMPF01554 InterPro: Uncharacterized domain UPF0013; Family membership YP_693276.1 identified by match to PFAM protein family HMMPF03977; Function unclear YP_693280.1 conserved hypothetical protein identified by match to PFAM protein family HMMPF01206 InterPro: Uncharacterized protein family UPF0033 YP_693281.1 (transmembrane transport protein) identified by match to PFAM protein family HMMPF04284, Family membership YP_693282.1 identified by sequencesimilarity YP_693283.1 produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine YP_693284.1 transcriptional regulator AraC family identified by match to PFAM protein family HMMPF00165 InterPro: AraC type helix-turn-helix; Function unclear YP_693285.1 identified by sequencesimilarity; InterPro: Response regulator receiver domain; Family membership YP_693286.1 (fatty oxidation complex alpha subunit, enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase / 3-hydroxybutyryl-CoA epimerase) identified by sequence similarity; InterPro: enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase / 3-hydroxybutyryl-CoA epimerase; Family membership YP_693287.1 (Acetyl CoA acetyltransferase) identified by sequence similarity; InterPro: Thiolase; High confidence in function and specificity YP_693289.1 Smr domain protein identified by match to PFAM protein family HMMPF01713 InterPro: Smr domain; Function unclear YP_693290.1 catalyzes the conversion of NADPH to NADH YP_693291.1 identified by match to PFAM protein family HMMPF00308 YP_693292.1 identified by sequencesimilarity YP_693293.1 identified by sequencesimilarity; InterPro: Phosphoribosylformylglycinamidine cyclo-ligase; High confidence in function and specificity YP_693294.1 identified by sequence similarity; InterPro: Phosphoribosylglycinamide formyltransferase; High confidence in function and specificity YP_693297.1 Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis YP_693298.1 identified by sequencesimilarity; InterPro: Mrp family; Family membership YP_693299.1 (eno) identified by sequencesimilarity; Hypothetical protein YP_693300.1 transcriptional regulator AraC family) identified by match to PFAM protein family HMMPF00165 InterPro: AraC type helix-turn-helix; Function unclear YP_693301.1 identified by match to PFAM protein family HMMPF01734 YP_693302.1 involved in uv protection and mutation. InterPro: UMUC family (DNA-repair) Pfam: impB/mucB/samB family; Family membership YP_693303.1 identified by sequencesimilarity; InterPro: Peptidase family S24; Family membership YP_693305.1 oxidoreductase identified by sequence similarity; Family membership YP_693306.1 identified by match to PFAM protein family HMMPF03602 InterPro: SAM (and some other nucleotide) binding motif YP_693307.1 identified by sequencesimilarity; InterPro: SLT domain murein-degrading enzyme; High confidence in function and specificity YP_693308.1 (conserved hypothetical protein, contains spermidine synthase domain) identified by sequence similarity YP_693311.1 (alpha/beta-hydrolase protein family, ) identified by sequence similarity; InterPro: Esterase/lipase/thioesterase family active site; Family membership YP_693312.1 (ttgR) (transcriptional regulator TtgR) identifiedby sequence similarity; InterPro: Bacterial regulatory proteins TetR family; Family membership YP_693314.1 identified by match to PFAM protein family HMMPF04055 InterPro: Domain of unknown function DUF85 YP_693315.1 Region start changed from 1824508 to 1824409 (-99 bases) YP_693316.1 identified by Glimmer2 YP_693318.1 sensor histidine kinase identified by match to PFAM protein family HMMPF02518 InterPro: Histidine kinase C-terminal; Function unclear YP_693319.1 Methionine-tRNA ligase activity; High confidence in function and specificity YP_693320.1 identified by sequencesimilarity; InterPro: Cyclic nucleotide-binding domain; Family membership YP_693321.1 deleted EC_number 4.1.2.1; (aldolase, ) identified by match to TIGR protein family HMMTIGR01086, InterPro: Class II Aldolase and Adducin N-terminal domain; Family membership YP_693322.1 (phosphohydrolase, HD domain protein family, ) identified by match to PFAM protein family HMMPF03466; Family membership YP_693326.1 identified by sequence similarity YP_693328.1 SPT; serine-pyruvate transaminase; serine-pyruvate aminotransferase; identified by sequencesimilarity; High confidence in function and specificity YP_693329.1 RnfA -related membrane protein identified by sequence similarity; High confidence in function and specificity YP_693330.1 identified by sequence similarity; InterPro: 4Fe-4S ferredoxin iron-sulfur binding domain cofactor binds 1 2fe-2s and 2 4fe-4s clusters (potential) belongs to the 4fe4s bacterial-type ferredoxin family. rnfb subfamily; High confidence in function and specificity YP_693331.1 (NADH dehydrogenase I F subunit) identified by sequence similarity; InterPro: Respiratory-chain NADH dehydrogenase 51 Kd subunit; High confidence in function and specificity YP_693332.1 identified by match to PFAM protein family HMMPF03116; Family membership YP_693333.1 electron transport complex protein rnfg belongs to the rnfg family; Family membership YP_693334.1 in Excherichia coli RsxABCDEG reduces SoxR which turns off induction of SoxS transcription factor in the absence of oxidizing agents; similar to the rnfABCDGE operon in Rhodobacter capsulatus involved in transferring electrons to nitrogenase YP_693335.1 hypothetical protein (conserved hypothetical protein) identified by sequencesimilarity YP_693336.1 (sodium/glutamate symport carrier protein, sodium-glutamate symporter, glutamate permease) identified by sequence similarity; identified by match to PFAM protein family HMMPF03616 and TIGRFAM protein family HMMTIGR00210 InterPro: Sodium/glutamate symporter; High confidence in function and specificity YP_693337.1 (endonuclease III),(DNA-(apurinic or apyrimidinic site)lyase)identified by match to PFAM protein family HMMPF00730 InterPro: HhH-GPD; High confidence in function and specificity YP_693338.1 dienelactone hydrolase family protein identified by sequence similarity; InterPro: Dienelactone hydrolase; Family membership YP_693339.1 (conserved hypothetical protein TIGR00257) identified by match to TIGR protein family HMMTIGR00257 YP_693341.1 High confidence in function and specificity YP_693342.1 (MazG nucleotide pyrophosphohydrolase domain family protein) identified by match to TIGR protein family HMMTIGR00444 InterPro: MazG family protein; Function unclear YP_693343.1 (GTP pyrophosphokinase) identified by match to PFAM protein family HMMPF02824 InterPro: RelA/SpoT family protein; High confidence in function and specificity YP_693344.1 Identified by match to PFAM protein family HMMPF03602.; Conserved hypothetical protein YP_693345.1 (oprB-2) (porin B) identified by sequencesimilarity YP_693346.1 catalyzes the formation of cysteine from 3-O-acetyl-L-serine and hydrogen sulfide YP_693347.1 (sensor histidine kinase/response regulator GacS) identified by sequence similarity; InterPro: Histidine kinase C-terminal; Family membership YP_693348.1 involved in the de novo synthesis of pyridoxine (Vitamin B6) YP_693349.1 identified by match to PFAM protein family HMMPF02565; High confidence in function and specificity YP_693350.1 identified by sequence similarity; InterPro: Type 2 KH domain; Family membership YP_693351.1 identified by sequence similarity; InterPro: Ribonuclease III family; High confidence in function and specificity YP_693353.1 (signal peptidase I) identified by sequence similarity; InterPro: Signal peptidase; High confidence in function and specificity YP_693354.1 binds to the ribosome on the universally-conserved alpha-sarcin loop YP_693355.1 alginate biosynthesis negative regulator serine protease AlgW, identified by sequence similarity; InterPro: Serine proteases trypsin family; High confidence in function and specificity YP_693356.1 identified by sequence similarity; High confidence in function and specificity YP_693357.1 (sigma factor algU regulatory protein AlgN) identified by match to PFAM protein family HMMPF03888; High confidence in function and specificity YP_693358.1 identified by match to PFAM protein family HMMPF03872 RseA_N; High confidence in function and specificity YP_693359.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor is involved in heat shock and oxidative stress response YP_693361.1 identified by sequencesimilarity; InterPro: Fumarate reductase/succinate dehydrogenase flavoprotein N-terminal; High confidence in function and specificity YP_693363.1 identified by match to PFAM protein family HMMPF03937 YP_693364.1 Family membership YP_693365.1 identified by match to PFAM protein family HMMPF00378 InterPro: Enoyl-CoA hydratase/isomerase; High confidence in function and specificity YP_693366.1 identified by match to PFAM protein family HMMPF03167; High confidence in function and specificity YP_693367.1 transcriptional regulator TetR family identified by match to PFAM protein family HMMPF00440; Family membership YP_693368.1 identified by sequencesimilarity; InterPro: Lysyl-tRNA synthetase class-2; High confidence in function and specificity YP_693369.1 identified by sequence similarity; High confidence in function and specificity YP_693371.1 identified by sequencesimilarity; InterPro: Single-stranded-DNA-specific exonuclease RecJ; High confidence in function and specificity YP_693372.1 includes enoyl-CoA hydratase, delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase, 3-hydroxyacyl-CoA dehydrogenase, and 3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities; forms a heterotetramer with FadA; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids YP_693373.1 FadA; fatty acid oxidation complex component beta; functions in a heterotetramer with FadB; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids YP_693378.1 Hypothetical protein YP_693379.1 DNA-cytosine methyltransferase identified by sequence similarity; InterPro: C-5 cytosine-specific DNA methylase; Specificity unclear YP_693380.1 (topA) (DNA topoisomerase I) identified by match to PFAM protein family HMMPF01131 InterPro: Prokaryotic DNA topoisomerase I YP_693381.1 conserved hypothetical protein identified by Glimmer2 YP_693382.1 curved-DNA-binding protein DnaJ family identified by sequence similarity; InterPro: DnaJ C terminal domain; High confidence in function and specificity YP_693383.1 activates fatty acids by binding to coenzyme A; may be involved in acyclic terpene utilization YP_693384.1 (CBS domain protein, ) identified by sequence similarity InterPro: CBS domain; Family membership YP_693385.1 (helicase ) identified by match to PFAM protein family HMMPF00580; Hypothetical protein YP_693386.1 Conserved hypothetical protein YP_693387.1 identified by sequence similarity; InterPro: SAM (and some other nucleotide) binding motif; Hypothetical protein YP_693388.1 identified by match to PFAM protein family HMMPF00520; Family membership YP_693393.1 (ABC efflux transporter, permease protein, ) identified by match to PFAM protein family HMMPF03824 InterPro: DUF214; Family membership YP_693394.1 (ABC transporter, ATP-binding protein, ) identified by sequencesimilarity; InterPro: AAA ATPase superfamily; Family membership YP_693397.1 identified by sequencesimilarity; InterPro: Ferric uptake regulator family; Family membership YP_693398.1 conserved hypothetical protein YP_693399.1 (CobW/P47K family protein, ) identified by sequencesimilarity; InterPro: Cobalamin synthesis protein/P47K; Family membership YP_693400.1 (DnaK suppressor protein homolog; C4-type zinc finger protein DksA/TraR family) identified by match to PFAM protein family HMMPF01258; Family membership YP_693402.1 (Carbonic anhydrases/acetyltransferases, isoleucine patch superfamilyprotein, ) identified by sequencesimilarity; InterPro: Bacterial transferase hexapeptide repeat; Family membership YP_693403.1 Catalyzes the reversible hydrolysis of the amide bond within dihydroorotate. This metabolic intermediate is required for the biosynthesis of pyrimidine nucleotides YP_693404.1 Phosphoglycolate phosphatase; Family membership YP_693406.1 (phosphoadenosine phosphosulfate reductase, 3'-phosphoadenylylsulfate reductase, PAPS reductase thioredoxin dependent, PADOPS reductase, PAPS sulfotransferase) identified by sequence similarity; identified by match to PFAM protein family HMMPF01507 and TIGRFAM protein family HMMTIGR00434 InterPro: Phosphoadenosine phosphosulfate reductase; High confidence in function and specificity YP_693407.1 (hypothetical signal peptide protein) identified by match to PFAM protein family HMMPF03734 YP_693408.1 Function unclear YP_693409.1 bfrA; exogenous ferric siderophore receptor,homologf of fepA (Abo_; Hypothetical protein YP_693410.1 (sensor histidine kinase) identified by match to PFAM protein family HMMPF02518 InterPro: Histidine kinase C-terminal; High confidence in function and specificity YP_693411.1 identified by match to PFAM protein family HMMPF00072; Specificity unclear YP_693412.1 Uncharacterized protein conserved in bacteria (COG 3295) YP_693414.1 Conserved hypothetical protein YP_693415.1 identified by match to PFAM protein family HMMPF00271 InterPro: DEAD/DEAH box helicase; High confidence in function and specificity YP_693417.1 identified by sequencesimilarity; InterPro: Nitroreductase family; Family membership YP_693419.1 Hypothetical protein YP_693420.1 esterified fatty acid cis/trans isomerase family protein identified by sequence similarity; Family membership YP_693421.1 (acyl-CoA dehydrogenase, C-terminal domain) identified by sequencesimilarity; InterPro: Acyl-CoA dehydrogenase; High confidence in function and specificity YP_693422.1 identified by match to PFAM protein family HMMPF02770 InterPro: Acyl-CoA dehydrogenase; Family membership YP_693423.1 (transcriptional regulator ArsR family) identified by match to PFAM protein family HMMPF01022 InterPro: Bacterial regulatory proteins ArsR family; Family membership YP_693424.1 (oxidoreductase FMN-binding) identified by match to PFAM protein family HMMPF00724 InterPro: NADH:flavin oxidoreductase/NADH oxidase; Conserved hypothetical protein YP_693425.1 (2,4-dienoyl-CoA reductase FadH) identified by sequencesimilarity; InterPro: NADH:flavin oxidoreductase/NADH oxidase; High confidence in function and specificity YP_693426.1 identified by sequencesimilarity; InterPro: Bacterial regulatory proteins TetR family HTH reporting nucleic acid binding motif; Family membership YP_693427.1 hydrolase alpha/beta fold family identified by match to TIGR protein family HMMTIGR01738 InterPro: Alpha/beta hydrolase fold; Specificity unclear YP_693428.1 identified by match to PFAM protein family HMMPF02518 InterPro: Histidine kinase C-terminal; Specificity unclear YP_693429.1 DNA-binding response regulator) identified by match to TIGR protein family HMMTIGR01387 InterPro: Response regulator receiver domain; Function unclear YP_693432.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation YP_693433.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis YP_693434.1 identified by match to PFAM protein family HMMPF04186 YP_693435.1 transcriptional regulator AraC family identified by match to PFAM protein family HMMPF00165 InterPro: AraC type helix-turn-helix; Family membership YP_693437.1 (oxidoreductase FAD-binding ) identified by sequencesimilarity; InterPro: Oxidoreductase FAD and NAD(P)-binding domain; Family membership YP_693438.1 transcriptional regulator TetR family identified by match to PFAM protein family HMMPF00440 InterPro: Bacterial regulatory proteins TetR family; Family membership YP_693439.1 (MaoC domain protein, ) identified by match to PFAM protein family HMMPF01575 InterPro: MaoC-like dehydratase domain; Family membership YP_693440.1 catalyzes the selenophosphate-dependent transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA YP_693441.1 phosphate ABC transporter periplasmicphosphate-binding protein identified by sequence similarity; Function unclear YP_693442.1 identified by match to TIGR protein family HMMTIGR00972 InterPro: AAA ATPase superfamily possibly phosphate transporter; Family membership YP_693444.1 (phenazine biosynthesis-like protein, ) identified by match to PFAM protein family HMMPF02567 InterPro: Phenazine biosynthesis PhzC/PhzF protein; Family membership YP_693445.1 (selenide water dikinase) identified by match to PFAM protein family HMMPF02769 InterPro: AIR synthase related protein YP_693448.1 member of the SPOUT superfamily of methyltransferases YP_693449.1 (potassium efflux system protein KefA ) identified by sequence similarity; InterPro: Uncharacterized protein family UPF0003 shows 36 38dentity to the (aefA) (potassium efflux system protein KefA, )in Pseudomonas putida KT2440 (PP5067) YP_693450.1 (hypothetical protein) identified by Glimmer2 YP_693451.1 (acetyl-CoA synthetase ) identified by sequence similarity; High confidence in function and specificity YP_693455.1 conserved hypothetical protein YP_693456.1 identified by match to PFAM protein family HMMPF04116 YP_693457.1 (ABC transporter, ATP-binding protein, ) identified by sequence similarity; InterPro: AAA ATPase superfamily; Family membership YP_693458.1 identified by sequencesimilarity YP_693459.1 Hypothetical protein YP_693460.1 identified by match to TIGR protein family HMMTIGR01259, TIGR00426; Family membership YP_693461.1 type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase YP_693464.1 (integration host factor beta subunit); Family membership YP_693465.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins YP_693466.1 identified by sequence similarity; InterPro: Cytidylate kinase; High confidence in function and specificity YP_693467.1 catalyzes the formation of 4-hydroxyphenylpyruvate from prephenate and the formation of tyrosine from arogenate and catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis YP_693468.1 catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis YP_693469.1 (P-protein including chorismate mutase and prephenate dehydratase) identified by sequence similarity; identified by match to PFAM protein family HMMPF01817 InterPro: Prephenate dehydratase (PDT); High confidence in function and specificity YP_693470.1 catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine YP_693471.1 (type II topoisomerase). identified by match to PFAM protein family HMMPF00521 InterPro: DNA gyrase/topoisomerase IV subunit A; High confidence in function and specificity YP_693472.1 Catalyzes the hydrolytic cleavage of a carbon-halogen bond in N-ethylammeline YP_693473.1 identified by match to PFAM protein family HMMPF01209 InterPro: ubiE/COQ5 methyltransferase; High confidence in function and specificity YP_693474.1 identified by match to PFAM protein family HMMPF00702; InterPro: Haloacid dehalogenase/epoxide hydrolase family; Family membership YP_693475.1 oxidoreductase short chaindehydrogenase/reductase family identified by match to TIGR protein family HMMTIGR01500 InterPro: Short-chain dehydrogenase/reductase (SDR) superfamily; Family membership YP_693477.1 Hypothetical protein YP_693478.1 identified by sequence similarity YP_693479.1 InterPro: ABC1 family probably involved in the biogenesis of ubiquinone; Family membership YP_693480.1 High similarity to predicted unusual protein kinase (COG0661); ABC transporter protein kinase (Q8F334) YP_693482.1 identified by sequence similarity YP_693484.1 identified by match to PFAM protein family HMMPF01230, InterPro: HIT (Histidine triad protein) family; Family membership YP_693488.1 identified by sequence similarity; InterPro: 3-5 exonuclease; High confidence in function and specificity YP_693489.1 identified by sequence similarity; InterPro: Phosphoglycerate mutase family; High confidence in function and specificity YP_693490.1 predicted by Glimmer/Critica YP_693492.1 InterPro: Acyl-CoA dehydrogenase pae:PA4435; Function unclear YP_693493.1 identified by sequence similarity; InterPro: RecR protein; High confidence in function and specificity YP_693494.1 identified by match to PFAM protein family HMMPF02575 InterPro: Conserved hypothetical protein 103 YP_693495.1 identified by sequence similarity; InterPro: AAA-protein (ATPases associated with various cellular activities); High confidence in function and specificity YP_693496.1 (Glyceraldehyde 3-phosphate dehydrogenase) identified by sequencesimilarity; InterPro: Glyceraldehyde 3-phosphate dehydrogenase; High confidence in function and specificity YP_693497.1 (ibpA) identified by sequencesimilarity; InterPro: Heat shock hsp20 (alpha crystallin) proteins family; Specificity unclear YP_693500.1 (transcriptional regulator PadR family) identified by sequence similarity YP_693501.1 Function unclear YP_693502.1 siderophore biosynthesis protein (transferase for other substituted phosphate groups) identified by sequence similarity; Function unclear YP_693503.1 (glycosyl transferase, ) identified by sequencesimilarity; Family membership YP_693504.1 non-ribosomal peptide synthase fragment, contains condensation, fatty-acid-CoA ligase and thioesterase domains. identified by sequence similarity; InterPro: AMP-dependent synthetase and ligase; Family membership YP_693505.1 Family membership YP_693506.1 InterPro: Integrase catalytic core; Family membership YP_693507.1 transposase OrfA identified by match to PFAM protein family HMMPF04218; Family membership YP_693508.1 Hypothetical protein YP_693511.1 (acetyl-CoA hydrolase/transferase family protein) identified by sequencesimilarity; Family membership YP_693512.1 identified by match to PFAM protein family HMMPF00893 InterPro: Integral membrane protein DUF7; Family membership YP_693513.1 CobW/P47K family protein identified by match to PFAM protein family HMMPF02492 InterPro: Cobalamin synthesis protein/P47K; Function unclear YP_693514.1 catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis YP_693516.1 identified by sequencesimilarity; InterPro: Carbon storage regulator; High confidence in function and specificity YP_693517.1 (aspartokinase, aspartate kinase monofunctional class) identified by sequence similarity; identified by match to PFAM protein family HMMPF00696; InterPro: Aspartokinase superfamily; High confidence in function and specificity YP_693518.1 (alanyl-tRNA synthetase)(Alanine--tRNA ligase) identified by sequence similarity; InterPro: Alanyl-tRNA synthetase; High confidence in function and specificity YP_693519.1 identified by sequence similarity; InterPro: Domain of unknown function DUF81; Specificity unclear YP_693520.1 identified by sequence similarity; InterPro: RecX regulatory protein; High confidence in function and specificity YP_693521.1 identified by sequence similarity; InterPro: RecA bacterial DNA recombination protein; High confidence in function and specificity YP_693522.1 identified by sequence similarity; InterPro: Competence-damaged protein; Family membership YP_693523.1 (conserved hypothetical protein TIGR01033) identified by match to TIGR protein family HMMTIGR01033 InterPro: Domain of unknown function DUF28 YP_693524.1 acyltransferase, homologous to ABO_2742, AtfA1 and to the ACIAD0832, wax ester synthase/ diacylglycerol acyltransferase of Acinetobacter sp. AP1; High confidence in function and specificity YP_693525.1 identified by match to PFAM protein family HMMPF01936 YP_693526.1 AMP-binding family protein identified by match to TIGR protein family HMMTIGR01734 InterPro: AMP-dependent synthetase and ligase; Family membership YP_693528.1 transposase OrfA identified by match to PFAM protein family HMMPF04218 InterPro: Transposase IS911 HTH and LZ region; Family membership YP_693529.1 identified by match to PFAM protein family HMMPF01624 InterPro: DNA mismatch repair protein MutS family N-terminal domain; High confidence in function and specificity YP_693530.1 identified by sequencesimilarity; InterPro: 4Fe-4S ferredoxin iron-sulfur binding domain; High confidence in function and specificity YP_693531.1 identified by sequencesimilarity; InterPro: Hpt domain The N-terminal third of this protein harbours a hpt domain.Similarity to rpfC proteins does only rely on this domain. Usually, rpfC proteins are composed of a histidine kinase domain at the N-terminus, a response regulatory domain in the central part and an hpt domain at the C-terminus.; Family membership YP_693532.1 InterPRO: Uncharacterized BCR (DUF703) YP_693534.1 (hypothetical protein) identified by match to PFAM protein family HMMPF04055 YP_693535.1 (hypothetical proteins) YP_693536.1 identified by sequence similarity; High confidence in function and specificity YP_693537.1 Conserved hypothetical protein YP_693538.1 (exodeoxyribonuclease V gamma subunit) identified by sequence similarity; High confidence in function and specificity YP_693539.1 (exodeoxyribonuclease V beta subunit) DNA helicase,ATP-dependent dsDNA/ssDNA exonuclease V subunit, ssDNA endonuclease identified by sequence similarity; InterPro: UvrD/REP helicase; High confidence in function and specificity YP_693540.1 (exodeoxyribonuclease V alpha subunit) identified by sequence similarity; InterPro: Viral (superfamily 1) RNA helicase; High confidence in function and specificity YP_693544.1 essential GTPase; functions in ribosome assembly; binds a unique part of the 23S rRNA; interacts with ribosomal protein L25(Ctc) YP_693545.1 identifiedby sequence similarity; Specificity unclear YP_693547.1 identified by match to PFAM protein family HMMPF04174 YP_693549.1 (type I restriction-modification system Ssubunit) identified by sequence similarity; InterPro: Restriction modification system type I; High confidence in function and specificity YP_693550.1 identified by sequencesimilarity; InterPro: Type I restriction-modification system M subunit; High confidence in function and specificity YP_693551.1 (DNA recombination protein, RmuC homolog) identified by match to PFAM protein family HMMPF02646 InterPro: DUF195 YP_693552.1 identified by sequencesimilarity; InterPro: DEAD/DEAH box helicase; High confidence in function and specificity YP_693553.1 Conserved hypothetical protein YP_693555.1 (conserved hypothetical protein) identified by match to PFAM protein family HMMPF00376 InterPro: Bacterial regulatory proteins MerR family YP_693556.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control YP_693557.1 identified by sequence similarity; High confidence in function and specificity YP_693558.1 identified by match to TIGR protein family HMMTIGR00468 InterPro: Phenylalanyl-tRNA synthetase alpha subunit; High confidence in function and specificity YP_693559.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit YP_693560.1 identified by match to PFAM protein family HMMPF01632 InterPro: Ribosomal protein L35; High confidence in function and specificity YP_693561.1 identified by sequencesimilarity; InterPro: Initiation factor 3; High confidence in function and specificity YP_693562.1 transcriptional regulator MarR family identified by match to PFAM protein family HMMPF03551 InterPro: Bacterial regulatory protein MarR family; Family membership YP_693563.1 monooxygenase, ,; Specificity unclear YP_693564.1 (major facilitator family transporter) identified by match to PFAM protein family HMMPF03977 YP_693565.1 identified by sequence similarity; InterPro: Catalase; High confidence in function and specificity YP_693567.1 (ABC transporter, ATP-binding protein, permease protein, ) identified by match to TIGR protein family HMMTIGR01291; Family membership YP_693568.1 (ABC transporter, ATP-binding protein/permease protein, ) identified by match to PFAM protein family HMMPF03772 InterPro: AAA ATPase superfamily; Family membership YP_693569.1 (HlyD family secretion protein) identified by match to TIGR protein family HMMTIGR01730 InterPro: HlyD family secretion protein Gram-negative bacteria produce a number of proteins which are secreted into the growth medium by a mechanism that does not require a cleaved N-terminal signal sequence. These proteins, while having different functions, require the help of two or more proteins for their secretion across the cell envelope. These secretion proteins include members belonging to the ABC transporter family (see the relevant entry IPR003439) and a protein belonging to a family which is currently composed the members:Hemolysin, Colicin V etc.; High confidence in function and specificity YP_693570.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway YP_693571.1 (inosine-5'-monophosphate dehydrogenase) identified by match to PFAM protein family HMMPF00478 InterPro: IMP dehydrogenase / GMP reductase; High confidence in function and specificity YP_693572.1 identified by match to PFAM protein family HMMPF02601; High confidence in function and specificity YP_693573.1 (sensor histidine kinase/response regulator, ) identified by match to PFAM protein family HMMPF02518 InterPro: Histidine kinase C-terminal; Family membership YP_693575.1 (conserved hypothetical protein) identified by sequencesimilarity YP_693576.1 (GTP-binding protein, ) identified by similary to Pfam family protein PF01926; High confidence in function and specificity YP_693577.1 identified by match to PFAM protein family HMMPF01011 InterPro: PQQ enzyme repeat YP_693578.1 identified by sequence similarity YP_693579.1 identified by sequencesimilarity; InterPro: Histidyl-tRNA synthetase; High confidence in function and specificity YP_693580.1 (1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphatesynthase) identified by sequence similarity; InterPro: GcpE protein .; High confidence in function and specificity YP_693582.1 identified by match to PFAM protein family HMMPF00515 InterPro: TPR repeat; Family membership YP_693583.1 Predicted Fe-S-cluster redox enzyme identified by match to PFAM protein family HMMPF04055, TIGR00048 InterPro: Conserved hypothetical protein 48 YP_693584.1 (nucleoside diphosphate kinase) identified by match to PFAM protein family HMMPF00334 InterPro: Nucleoside diphosphate kinase; High confidence in function and specificity YP_693585.1 with SufCD activates cysteine desulfurase SufS YP_693586.1 ABC-type transport system involved in Fe-S cluster assembly, ATPase component; High confidence in function and specificity YP_693587.1 Conserved hypothetical protein, ABC transporter permease component, possibly involved in Fe-S cluster assembly; High confidence in function and specificity YP_693588.1 identified by sequence similarity; identified by match to PFAM protein family HMMPF00266; InterPro: Aminotransferase class-V; High confidence in function and specificity YP_693589.1 identified by sequence similarity; InterPro: Hypothetical hesB/yadR/yfhF family; Family membership YP_693590.1 Family membership YP_693591.1 SufE protein probably involved in Fe-S center assembly; Family membership YP_693592.1 identified by sequence similarity; identified by match to PFAM potein family HMMPF00266; InterPro: Aminotransferase class-V; High confidence in function and specificity YP_693593.1 identified by match to PFAM protein family HMMPF02082 InterPro: Uncharacterized protein family UPF0074; Family membership YP_693595.1 Hypothetical protein YP_693596.1 NAD-dependent protein deacetylases, SIR2 family; SIR2-like transcriptional silencer protein identified by match to PFAM protein family HMMPF02146; Family membership YP_693597.1 identified by match to TIGR protein family HMMTIGR00042 InterPro: Ham1 family; Family membership YP_693598.1 conserved hypothetical protein distantly YP_693599.1 identify by sequence similarity YP_693601.1 (conserved hypothetical protein) identified by sequence similarity YP_693602.1 LemA contains an amino terminal predicted transmembrane helix. It has been predicted that the small amino terminus is extracellular. The exact molecular function of this protein is uncertain.; Conserved hypothetical protein YP_693603.1 (conserved hypothetical protein) identified by sequence similarity YP_693605.1 conserved hypothetical protein YP_693606.1 identified by match to PFAM protein family HMMPF01738 InterPro: Dienelactone hydrolase; Family membership YP_693607.1 identified by sequence similarity; Specificity unclear YP_693608.1 identified by sequence similarity; InterPro: Binding-protein-dependent transport systems inner membrane component; Specificity unclear YP_693609.1 Specificity unclear YP_693610.1 identified by match to PFAM protein family HMMPF00595 YP_693612.1 urea carboxylase; urease (ATP-hydrolysing); urea amidolyase/allophanate hydrolase [EC:6.3.4.6 3.5.1.54] identified by sequence similarity; InterPro: DUF183; Family membership YP_693613.1 (gcd) (glucose dehydrogenase (pyrroloquinoline-quinone)) identified by match to PFAM protein family HMMPF01011; Hypothetical protein YP_693614.1 transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA YP_693615.1 (estB) identified by sequence similarity; InterPro: Phospholipase/Carboxylesterase; Family membership YP_693616.1 (conserved hypothetical protein YP_693617.1 identified by match to PFAM protein family HMMPF04238 InterPro: Cytochrome c oxidase subunit III; High confidence in function and specificity YP_693618.1 identified by sequence similarity; Function unclear YP_693619.1 identified by match to TIGR protein family HMMTIGR00780 InterPro: Cytochrome c oxidase subunit I; High confidence in function and specificity YP_693620.1 identified by match to PFAM protein family HMMPF00034; High confidence in function and specificity YP_693621.1 identified by sequencesimilarity YP_693622.1 (conserved hypothetical protein) identified by sequencesimilarity YP_693624.1 (Sco1/SenC family protein) identified by match to PFAM protein family HMMPF00578 YP_693625.1 identified by similarity to Pfam protein family PF02628.; High confidence in function and specificity YP_693626.1 (UbiA prenyltransferase family, ) identified by sequence similarity; InterPro: UbiA prenyltransferase; Family membership YP_693627.1 (membrane protein ) identified by sequence similarity; Function unclear YP_693628.1 (ThiJ/PfpI family protein) identified by match to TIGR protein family HMMTIGR01382 conserved hypothetical protein with similarity to (ThiJ/PfpI family protein) YP_693629.1 (protease, ) identified by match to PFAM protein family HMMPF04066 InterPro: Peptidase family M48; Family membership YP_693632.1 Region start changed from 2189147 to 2189525 (-378 bases) YP_693633.1 identified by match to TIGRFAM protein family HMMTIGR00813; InterPro: Sodium:solute symporter family; Family membership YP_693634.1 High confidence in function and specificity YP_693635.1 Conserved hypothetical protein, by combining results from PsiBlast SP, Blast2p vs KEGG, PsiBlast Putida, InterPro, Blast2p vs COG, TIGRFAM. YP_693636.1 (conserved hypothetical protein) identified by sequencesimilarity YP_693637.1 (plsC) identified by sequence similarity; InterPro: Phospholipid and glycerol acyltransferase (from motifs_6.msf); High confidence in function and specificity YP_693638.1 identified by match to TIGR protein family HMMTIGR01500 InterPro: Short-chain dehydrogenase/reductase (SDR) superfamily; High confidence in function and specificity YP_693639.1 (heavy metal RND efflux outer membrane proteinCzcC family) identified by sequencesimilarity YP_693640.1 identified by sequencesimilarity; InterPro: DEAD/DEAH box helicase; High confidence in function and specificity YP_693641.1 identified by match to PFAM protein family HMMPF00581 InterPro: Rhodanese/cdc25 fold; Family membership YP_693642.1 Outer membrane protein W precursor., OmpW family; Specificity unclear YP_693644.1 identified by match to PFAM protein family HMMPF02562 InterPro: PhoH-like protein; Specificity unclear YP_693645.1 predicted by Glimmer/Critica YP_693649.1 (phaI) (ring-hydroxylation complex protein 4) identified by sequence similarity YP_693650.1 (transporter MgtC family) identified by sequencesimilarity YP_693651.1 (oxidoreductase FMN-binding) identified by match to TIGR protein family HMMTIGR00137; Function unclear YP_693653.1 (Sco1/SenC family protein) identifiedby sequence similarity; Family membership YP_693654.1 catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A) YP_693655.1 identified by match to PFAM protein family HMMPF02562 InterPro: PhoH-like protein; High confidence in function and specificity YP_693656.1 identified by match to TIGR protein family HMMTIGR00043 InterPro: Uncharacterized protein family UPF0054 YP_693657.1 identified by sequencesimilarity; InterPro: CBS domain; Function unclear YP_693659.1 InterPro: B-box zinc finger domain YP_693660.1 (cutE) identified by match to TIGR protein family HMMTIGR00546 InterPro: Apolipoprotein N-acyltransferase; Hypothetical protein YP_693661.1 identified by match to PFAM protein family HMMPF00753; Family membership YP_693662.1 identified by sequencesimilarity YP_693663.1 Sulphate anion transporter, Sulfate transporter family, sulP: sulfate permease; Conserved hypothetical protein YP_693664.1 Uncharacterized protein conserved in bacteria InterPRO: Protein of unknown function (DUF442) YP_693665.1 Sulfate transporter 1.1 (High-affinity sulfate transporter 1) (Hst1At) (AST101)., Sulphate anion transporter, Sulfate transporter family, TIGRFAM:sulP: sulfate permease; High confidence in function and specificity YP_693666.1 identified by match to PFAM protein family HMMPF02698 InterPro: Domain of unknown function DUF218 YP_693667.1 (isoleucyl-tRNA synthetase) identified by sequencesimilarity; InterPro: Leucyl-tRNA synthetase; High confidence in function and specificity YP_693668.1 Function unclear YP_693669.1 identified by sequencesimilarity; High confidence in function and specificity YP_693671.1 (gamma-glutamyl phosphate reductase, glutamate-5-semialdehyde dehydrogenase, glutamyl-gamma-semialdehyde dehydrogenase) identified by sequence similarity; InterPro: Aldehyde dehydrogenase family; High confidence in function and specificity YP_693672.1 Probable nicotinate-nucleotide adenylyltransferase (Deamido-NAD(+) pyrophosphorylase) (Deamido-NAD(+) diphosphorylase) (Nicotinate mononucleotide adenylyltransferase) (NaMN adenylyltransferase) TIGR00482; InterPro: Cytidylyltransferase; Conserved hypothetical protein YP_693673.1 identified by match to PFAM protein family HMMPF02410; Family membership YP_693674.1 (conserved hypothetical protein TIGR00246) identified by match to PFAM protein family HMMPF02590 InterPro: DUF163 YP_693675.1 MrdA penicillin-binding protein 2, ,InterPro: Penicillin binding protein transpeptidase domain; High confidence in function and specificity YP_693676.1 identified by sequence similarity; InterPro: Cell cycle proteins; High confidence in function and specificity YP_693677.1 identified by sequencesimilarity; murein-degrading enzyme. catalyzes the cleavage of the glycosidic bonds between n-acetylmuramic acid and n-acetylglucosamine residues in peptidoglycan. may play a role in recycling of muropeptides during cell elongation and/or cell division.; High confidence in function and specificity YP_693678.1 identified by sequencesimilarity; This is a family of bacterial lipoproteins. The function of RlpA is not well understood, but it has been shown to act as a prc mutant suppressor in Escherichia coli [MEDLINE:96165273]. This family contains a conserved region in the middle of RlpA.; Function unclear YP_693679.1 (D-alanyl-D-alanine carboxypeptidase) identified by sequencesimilarity; InterPro: D-alanyl-D-alanine carboxypeptidase 1 (S11) family; High confidence in function and specificity YP_693680.1 (D-alanine aminotransferase, D-aspartate aminotransferase, D-amino acid aminotransferase, D-amino acid transaminase) identified by sequence similarity; identified by match to PFAM protein family HMMPF01063 InterPro: Aminotransferases class-IV; High confidence in function and specificity YP_693683.1 identified by match to TIGR protein family HMMTIGR00214; High confidence in function and specificity YP_693684.1 catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group YP_693685.1 (D-alanyl-D-alanine carboxypeptidase) identified by match to PFAM protein family HMMPF02113 InterPro: D-Ala-D-Ala carboxypeptidase 3 (S13) family; High confidence in function and specificity YP_693687.1 identified by match to PFAM protein family HMMPF01618 InterPro: MotA/TolQ/ExbB proton channel family; High confidence in function and specificity YP_693688.1 identified by sequence similarity InterPro: Biopolymer transport protein ExbD/TolR; Function unclear YP_693689.1 identified by sequence similarity InterPro: Biopolymer transport protein ExbD/TolR; Family membership YP_693690.1 (tonB) (ferric siderophore transport system periplasmicbinding protein TonB) identified by sequence similarity; InterPro: Proline-rich region; High confidence in function and specificity YP_693691.1 (conserved hypothetical protein); Family membership YP_693692.1 (aromatic acid decarboxylase, ) identified by match to PFAM protein family HMMPF02441; Family membership YP_693694.1 (mpl) (UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso- diaminopimelate ligase) identified by match to PFAM protein family HMMPF01225 InterPro: Cytoplasmic peptidoglycan synthetases N-terminal; High confidence in function and specificity YP_693695.1 identified by sequencesimilarity; InterPro: Esterase/lipase/thioesterase family active site; High confidence in function and specificity YP_693696.1 identified by sequence similarity; High confidence in function and specificity YP_693697.1 identified by sequencesimilarity; Conserved hypothetical protein YP_693698.1 formamidase (EC 3.5.1.49) (formamide amidohydrolase) InterPro: Acetamidase/Formamidase; High confidence in function and specificity YP_693699.1 (chaperone-associated ATPase, ) identified by match to PFAM protein family HMMPF02861 InterPro: AAA ATPase superfamily; High confidence in function and specificity YP_693700.1 aliphatic amidase; catalyzes the hydrolysis of short-chain aliphatic amides to their organic acids and can also transfer the acyl moiety of short-chain amides to hydroxylamine to form hydroxamates YP_693701.1 (amino acid ABC transporter, ATP-binding protein, ) identified by sequence similarity and by match to PFAM protein family HMMPF00005; InterPro: AAA ATPase superfamily; Specificity unclear YP_693702.1 (branched-chain amino acid ABC transporter, ATP-binding protein) identified by sequence similarity and by match to PFAM protein family HMMPF00005; InterPro: AAA ATPase superfamily; High confidence in function and specificity YP_693703.1 (branched-chain amino acid ABC transporter,permease protein) identified by sequence similarity and by match to PFAM protein family HMMPF02653; InterPro: Binding-system dependent bacterial transporters (araH livH/limM families); Family membership YP_693704.1 identified by match to PFAM protein family HMMPF02653; InterPro: Binding-system dependent bacterial transporters (araH livH/limM families); Family membership YP_693705.1 (ABC transporter, periplasmic substrate-binding protein ) identified by sequence similarity; Family membership YP_693706.1 unknown EC_number 21.7.3.11; (two-component sensor histidine kinase protein, ) identified by match to PFAM protein family HMMPF03596 InterPro: Permeases for cytosine/purines uracil thiamine allantoin; Family membership YP_693707.1 identified by match to PFAM protein family HMMPF00072 InterPro: Response regulator receiver domain; High confidence in function and specificity YP_693709.1 catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis YP_693710.1 identified by match to PFAM protein family HMMPF00860 InterPro: Xanthine/uracil permeases family; High confidence in function and specificity YP_693711.1 identified by sequencesimilarity; InterPro: Phosphoribosyl transferase; Family membership YP_693712.1 (ATP-dependent RNA helicase DEAD box family) identified by match to PFAM protein family HMMPF00271 InterPro: peptidoglycan binding domain 1 YP_693713.1 identified by similarity to PFAMB, PB095705 PB094266 PB093724 PB092780 PB092388 PB091758 PB086012 PB074034 PB071888 PB045826 PB027182 PB012820 PB012628 PB009308 PB006481; InterPro: Rhodanese/cdc25 fold; Family membership YP_693714.1 (inorganic pyrophosphatase) identified by sequencesimilarity; InterPro: Inorganic pyrophosphatase belongs to the ppase family; High confidence in function and specificity YP_693715.1 Transcriptional regulator, AraC family InterPro: AraC type helix-turn-helix HTH reporting nucleic acid binding motif; Family membership YP_693717.1 (hypothetical protein) identified by sequence similarity; InterPro: SAM (and some other nucleotide) binding motif YP_693718.1 identify by sequence similarity; High confidence in function and specificity YP_693719.1 Hypothetical protein YP_693720.1 identified by match to PFAM protein family HMMPF00512 InterPro: Histidine kinase C-terminal; Family membership YP_693721.1 (Transcriptional regulatory protein, ) identified by match to TIGR protein family HMMTIGR01387 InterPro: Response regulator receiver domain; Family membership YP_693722.1 identified by sequencesimilarity; InterPro: ApbE family; Family membership YP_693726.1 (thioredoxin family protein, ) identified by sequence similarity; InterPro: Thioredoxin; High confidence in function and specificity YP_693727.1 identified by match to PFAM protein family HMMPF00085 InterPro: Cytochrome c biogenesis protein transmembrane region; High confidence in function and specificity YP_693728.1 catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis YP_693729.1 identified by sequence similarity; InterPro: Acetyl-CoA biotin carboxyl carrier protein; Hypothetical protein YP_693730.1 (acetyl-CoA carboxylase, biotin carboxylase) identified by sequence similarity; InterPro: Acetyl-CoA carboxylase, biotin carboxylase; High confidence in function and specificity YP_693731.1 identified by sequencesimilarity; High confidence in function and specificity YP_693733.1 (TIM-barrel protein NifR3 family, ) identified by match to PFAM protein family HMMPF04131 InterPro: TIM-barrel protein nifR3 family; Function unclear YP_693734.1 identified by sequencesimilarity; InterPro: Helix-turn-helix Fis-type; High confidence in function and specificity YP_693735.1 (phosphoribosylaminoimidazolecarboxamideformyltrans feras e/IMP cyclohydrolase) identified by sequence similarity; High confidence in function and specificity YP_693736.1 (phosphoribosylamine--glycine ligase) identified by match to TIGR protein family HMMTIGR00877 InterPro: Phosphoribosylglycinamide synthetase; High confidence in function and specificity YP_693737.1 (cytochrome c551 peroxidase ) identified by match to PFAM protein family HMMPF03150 InterPro: Cyclic nucleotide-binding domain; Family membership YP_693738.1 identified by match to PFAM protein family HMMPF04171; Family membership YP_693739.1 AAA-protein (ATPases associated with various cellular activities); Family membership YP_693740.1 identified by match to PFAM protein family HMMPF03232 YP_693741.1 S-adenosylmethionine provides the aminopropyl moiety required for spermidine biosynthesis from putrescine YP_693742.1 identified by sequence similarity YP_693743.1 complexes with cyclic AMP and binds to specific DNA sites near the promoter to regulate the transcription of several catabolite-sensitive operons YP_693744.1 identified by sequence similarity; identified by match to PFAM protein family HMMPF00218 InterPro: Indole-3-glycerol phosphate synthase; High confidence in function and specificity YP_693745.1 identified by sequence similarity; identified by match to PFAM protein family HMMPF00591; InterPro: Glycosyl transferase family; High confidence in function and specificity YP_693746.1 (anthranilate synthase component II, glutamine amidotransferase) identified by sequence similarity; identified by match to PFAM protein family HMMPF00117 and TIGRFAM protein family HMMTIGR00566; High confidence in function and specificity YP_693747.1 identified by sequence similarity; identified by match to PFAM protein families HMMPF00425 and HMMPF04715 InterPro: Anthranilate synthase component I and chorismate binding enzyme; High confidence in function and specificity YP_693750.1 (conserved hypothetical protein) identified by Glimmer2 YP_693751.1 identified by match to PFAM protein family HMMPF00072 InterPro: Response regulator receiver domain; High confidence in function and specificity YP_693752.1 (two-component, sensor histidine protein kinase, ) identified by match to PFAM protein family HMMPF04093 InterPro: Histidine kinase C-terminal; High confidence in function and specificity YP_693753.1 InterPro: SURF1 family; Family membership YP_693754.1 identified by sequence similarity; High confidence in function and specificity YP_693755.1 identified by sequence similarity; InterPro: Cytochrome c oxidase subunit III catalytic activity: ubiquinol-8 + o(2) = ubiquinone-8 + h(2)o; High confidence in function and specificity YP_693756.1 identified by match to TIGR protein family HMMTIGR00780 InterPro: Cytochrome c oxidase subunit I; High confidence in function and specificity YP_693757.1 identified by sequence similarity; InterPro: Cu(A) centre of cytochrome c oxidase subunit II and nitrous oxide reductase; High confidence in function and specificity YP_693758.1 (metabolite transport transmembrane protein, ) identified by sequencesimilarity; InterPro: General substrate transporters; High confidence in function and specificity YP_693759.1 identified by match to TIGR protein family HMMTIGR01317 InterPro: NADH:flavin oxidoreductase/NADH oxidase; High confidence in function and specificity YP_693760.1 identified by match to PFAM protein family HMMPF03551 InterPro: Protein of unknown function DUF24 YP_693761.1 identified by match to PFAM protein family HMMPF00877 InterPro: NLP/P60; Function unclear YP_693762.1 identified by match to TIGR protein family HMMTIGR01740 InterPro: Ribulose-phosphate 3-epimerase; High confidence in function and specificity YP_693763.1 identified by sequencesimilarity; InterPro: ADP-glucose pyrophosphorylase; Family membership YP_693765.1 (outer membrane ferric siderophore receptor) identified by match to PFAM protein family HMMPF00593 shows little homology to an organic solvent tolerance protein OstA precursor determines n-hexane tolerance. involved in outer membrane permeability. essential for envelope biogenesis. could be part of a targeting/usher system for outer membrane components (by similarity). YP_693766.1 (Survival protein surA precursor (Peptidyl-prolyl cis-trans isomerase surA) identified by sequence similarity; InterPro: PpiC-type peptidyl-prolyl cis-trans isomerase; High confidence in function and specificity YP_693767.1 identified by match to PFAM protein family HMMPF04166; High confidence in function and specificity YP_693768.1 identified by match to PFAM protein family HMMPF00398 InterPro: Ribosomal RNA adenine dimethylase; Family membership YP_693769.1 protein associated with Co2+ and Mg2+ efflux YP_693770.1 hydrolyzes P(1),P(4)-bis(5'-adenosyl) tetraphosphate to form 2 ADP YP_693771.1 (membrane protein, ) identified by match to PFAM protein family HMMPF04103 InterPro: Integral membrane protein DUF6; Function unclear YP_693772.1 (tRNA nucleotidyltransferase ) identifiedby sequence similarity; InterPro: Poly A polymerase family; Family membership YP_693773.1 Dehydrogenases with different specificities identified by sequence similarity; InterPro: Short-chain dehydrogenase/reductase (SDR) superfamily; High confidence in function and specificity YP_693776.1 (7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinas e) identified by sequencesimilarity; InterPro: 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase; Family membership YP_693777.1 identified by sequencesimilarity; InterPro: Dihydroneopterin aldolase; High confidence in function and specificity YP_693778.1 (conserved hypothetical protein TIGR00023) InterPRO: Domain of unknown function DUF205 YP_693779.1 identified by sequence similarity; InterPro: Glycoprotease (M22) metallo-protease family; Family membership YP_693780.1 identified by sequencesimilarity; InterPro: Ribosomal protein S21; High confidence in function and specificity YP_693781.1 (conserved hypothetical protein TIGR00281) identified by match to PFAM protein family HMMPF04079 InterPro: DUF186 YP_693782.1 identified by match to PFAM protein family HMMPF01807 InterPro: CHC2 zinc finger; High confidence in function and specificity YP_693783.1 identified by sequence similarity; InterPro: Sigma-70 factor family; High confidence in function and specificity YP_693784.1 identified by sequencesimilarity; InterPro: Phage integrase; High confidence in function and specificity YP_693785.1 identified by sequence similarity YP_693788.1 predicted by Glimmer/Critica YP_693789.1 predicted by Glimmer/Critica YP_693790.1 (potassium efflux system protein KefA ) identified by sequence similarity YP_693791.1 predicted by Glimmer/Critica YP_693792.1 identified by sequence similarity YP_693793.1 Region start changed from 2358473 to 2358482 (-9 bases) YP_693794.1 identified by sequence similarity; InterPro: ParA family ATPase; Family membership YP_693795.1 Transcriptional repressor protein, probably korB; Family membership YP_693796.1 predicted by Glimmer/Critica YP_693797.1 predicted by Glimmer/Critica YP_693798.1 (penicillin-binding protein) identified by sequence similarity; InterPro: Penicillin binding protein transpeptidase domain penicillin-binding protein 1a (pbp-1a) (pbp1a) [includes: penicillin- insensitive transglycosylase (EC 2.4.2.-) (peptidoglycan tgase); penicillin-sensitive transpeptidase (EC 3.4.-.-) (dd-transpeptidase)].; High confidence in function and specificity YP_693799.1 (oxalate/formate antiporter ) identified by sequencesimilarity YP_693800.1 predicted by Glimmer/Critica YP_693801.1 (transposase subunit B, ) identified by sequencesimilarity; InterPro: Integrase catalytic core; High confidence in function and specificity YP_693802.1 (transposase, ) identified by match to PFAM protein family HMMPF04218 InterPro: Transposase IS911 HTH and LZ region; High confidence in function and specificity YP_693803.1 conserved hypothetical protein that shows an Ankyrin-repeat InterPro: Ankyrin-repeat YP_693804.1 conserved hypothetical protein identified by match to PFAM protein family HMMPF00012 InterPro: Heat shock protein hsp70 YP_693806.1 exhibits an RNA-dependent ATPase activity, specifically stimulated by bacterial 23S rRNA YP_693807.1 siderophore biosynthesis protein identified by sequence similarity; InterPro: Holo-acyl carrier protein synthase; Conserved hypothetical protein YP_693808.1 (penicillin-binding protein 2) identified by match to PFAM protein family HMMPF00905; High confidence in function and specificity YP_693809.1 Region start changed from 2380063 to 2380003 (-60 bases) region start changed to correct the mistake during contig update YP_693810.1 identify by sequence similarity.; High confidence in function and specificity YP_693811.1 (ferrioxamine receptor ) identified by sequence similarity; InterPro: TonB-dependent receptor protein; High confidence in function and specificity YP_693812.1 (peptide synthetase, ); identified by sequence similarity; High confidence in function and specificity YP_693813.1 (peptide synthetase); identified by sequence similarity; High confidence in function and specificity YP_693814.1 (MbtH-like protein, ) by similarity to PFAM family PF03621; Family membership YP_693815.1 efflux pump for the antibacterial peptide microcin J25 YP_693816.1 (transcriptional regulator, ) identified by match to PFAM protein family HMMPF00440; Family membership YP_693817.1 identified by sequence similarity; High confidence in function and specificity YP_693818.1 identified by match to PFAM protein family HMMPF00441 InterPro: Acyl-CoA dehydrogenase; High confidence in function and specificity YP_693819.1 (glutamate dehydrogenase) identified by sequence similarity.; High confidence in function and specificity YP_693820.1 converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer YP_693821.1 identified by sequence similarity YP_693822.1 identified by match to PFAM protein family HMMPF00441 InterPro: Acyl-CoA dehydrogenase; High confidence in function and specificity YP_693824.1 ( outer membrane phospholipase A precursor, ) InterPro: Phospholipase A1; Family membership YP_693826.1 (transcriptional regulator, ) identified by match to PFAM protein family HMMPF00165 InterPro: AraC type helix-turn-helix; Family membership YP_693827.1 (monooxygenase, ) identified by sequence similarity; InterPro: Flavin-containing monooxygenase (FMO); High confidence in function and specificity YP_693828.1 (lipase/esterase family protein) identified by sequence similarity; InterPro: Esterase/lipase/thioesterase/carboxlesterase family active site; High confidence in function and specificity YP_693829.1 (short chain dehydrogenase/reductase, ) identified by sequence similarity; InterPro: Short-chain dehydrogenase/reductase (SDR) superfamily; High confidence in function and specificity YP_693831.1 (hydrolase alpha/beta fold family, ) identified by match to TIGR protein family HMMTIGR01738 InterPro: Alpha/beta hydrolase fold; Family membership YP_693832.1 oxidoreductase short chaindehydrogenase/reductase family identified by match to TIGR protein family HMMTIGR01500 InterPro: Short-chain dehydrogenase/reductase (SDR) superfamily; Family membership YP_693834.1 (hit-2) identified by match to PFAM protein family HMMPF01230, InterPro: HIT (Histidine triad protein) family; Family membership YP_693835.1 identified by sequence similarity YP_693836.1 (transcriptional regulator, ) identified by match to PFAM protein family HMMPF03466 InterPro: NodD transcription activator carboxyl terminal region,Bacterial regulatory protein, LysR family HTH reporting nucleic acid binding motif; Family membership YP_693837.1 homologous to PA3385 and PP4470, identified by match to PFAM protein family HMMPF03869; Specificity unclear YP_693838.1 identified by sequence similarity; InterPro: Domain of unknown function DUF9; Family membership YP_693839.1 flavohemoprotein; catalyzes the formation of nitrate from nitric oxide; can also catalyze the reduction of dihydropteridine YP_693840.1 (Transcriptional regulator, ) identified by match to PFAM protein family HMMPF02082 InterPro: Uncharacterized protein family UPF0074; Family membership YP_693841.1 predicted by Glimmer/Critica YP_693842.1 predicted by Glimmer/Critica YP_693843.1 (transcriptional regulator, ) identified by match to PFAM protein family HMMPF03466 InterPro: Bacterial regulatory protein LysR family HTH reporting nucleic acid binding motif; Family membership YP_693844.1 identified by sequence similarity. InterPro: FAD-binding domain; High confidence in function and specificity YP_693845.1 identified by similarity to Pfam protein families PF01077 and PF03460 InterPro: Nitrite and sulfite reductase; High confidence in function and specificity YP_693846.1 (cysI-2); identified by similarity to Pfam protein families PF01077 and PF03460; High confidence in function and specificity YP_693847.1 DsrE/DsrF-like family protein, Pfam:DrsE; Family membership YP_693848.1 Conserved hypothetical protein YP_693850.1 (conserved hypothetical protein) identified by sequencesimilarity; InterPro: 2-nitropropane dioxygenase; Family membership YP_693851.1 Region start changed from 2434194 to 2434095 (-99 bases) YP_693852.1 identified by match to PFAM protein family HMMPF02743 InterPro: Metal dependent phosphohydrolase HD domain; Family membership YP_693853.1 identified by sequence similarity; High confidence in function and specificity YP_693854.1 PR-AMP cyclohydrolase; functions in histidine biosynthesis from PRPP; converts 1-(5-phosphoribosyl)-AMP to 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxyamide during the histidine biosynthesis pathway; binds zinc and magnesium; forms homodimers YP_693855.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA YP_693857.1 (conserved hypothetical protein TIGR00278) identified by sequence similarity; InterPro: Domain of unknown function DUF37 YP_693858.1 identified by match to PFAM protein family HMMPF00593; Specificity unclear YP_693861.1 identified by match to PFAM protein family HMMPF00165; Family membership YP_693862.1 identified by match to PFAM protein family HMMPF04279 and TIGRFAM protein family HMMTIGR00813; InterPro: Sodium:solute symporter family; Family membership YP_693864.1 similar protein in Methanocaldococcus converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate as the first step in methanopterin biosynthesis YP_693865.1 (conserved hypothetical protein) identified by sequence similarity; InterPro: TPR repeat YP_693866.1 TRAP dicarboxylate transporter DctP subunit. identified by sequencesimilarity. Pfam: SBP_bac7: Bacterial extracellular solute-binding protein, family 7; Family membership YP_693867.1 TRAP-type C4-dicarboxylate transport system, dctM subunit. Identified by sequence similarity; TMHMM: reporting 9 transmembrane helices TIGRFAM:dctM; High confidence in function and specificity YP_693868.1 TRAP-type C4-dicarboxylate transport system, small permease component. identified by sequence similarity. Pfam:Tripartite ATP-independent periplasmic transporters,DctQ component TMHMM: reporting 5 transmembrane helices; High confidence in function and specificity YP_693869.1 (transcriptional regulator, MarR family) identified by match to PFAM protein family HMMPF03551 InterPro: Bacterial regulatory protein MarR family; Family membership YP_693870.1 L-2,4-diaminobutyric acid acetyltransferase (EC 2.3.1.-) identified by sequence similarity; High confidence in function and specificity YP_693871.1 catalyzes the reversible formation of diaminobutyrate and 2-oxoglutarate from glutamate and L-aspartic beta-semialdehyde YP_693872.1 N-acetyldiaminobutyrate dehydratase; catalyzes the formation of the osmoprotectant ecotoine from gamma-N-acetyl-alpha,gamma-diaminobutyric acid YP_693874.1 identified by sequence similarity; InterPro: Response regulator receiver domain; Family membership YP_693875.1 (two-component protein: Na-solute symporter/sensory box histidinekinase/response regulator ) identified by match to PFAM protein family HMMPF02518 and HMMPF00072; InterPro: Sodium:solute symporter family TMHMM: reportin 12 transmembrane helices; Family membership YP_693876.1 3'-5' exonuclease of DNA polymerase III YP_693877.1 identified by sequence similarity; Family membership YP_693878.1 Na+/solute symporter, Sodium:solute symporter family, sss: SSS sodium solute transporter superfamily; Hypothetical protein YP_693882.1 (Dihydrouridine synthase protein family, ); Function unclear YP_693884.1 identified by match to PFAM protein family HMMPF02609 InterPro: Exonuclease VII small subunit; High confidence in function and specificity YP_693885.1 (gppS) identified by sequence similarity; InterPro: Polyprenyl synthetase; Family membership YP_693886.1 identified by sequencesimilarity; InterPro: Transketolase; High confidence in function and specificity YP_693887.1 identified by sequence similarity; InterPro: Domain of unknown function DUF9; High confidence in function and specificity YP_693888.1 identified by sequence similarity; High confidence in function and specificity YP_693889.1 (thiamine monophosphate kinase) identified by sequencesimilarity; InterPro: AIR synthase related protein; High confidence in function and specificity YP_693890.1 identified by match to PFAM protein family HMMPF01029 InterPro: Antitermination protein NusB; High confidence in function and specificity YP_693891.1 identified by match to TIGR protein family HMMTIGR00114 InterPro: 67-dimethyl-8-ribityllumazine synthase; High confidence in function and specificity YP_693892.1 bifunctional enzyme DHBP synthase/GTP cyclohydrolase II-like protein; functions in riboflavin synthesis YP_693893.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine YP_693894.1 (riboflavin biosynthesis protein RibD) identified by sequence similarity; InterPro: Riboflavin biosynthesis protein RibD; High confidence in function and specificity YP_693895.1 Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains Pfam: Sigma-70 region 3; Family membership YP_693896.1 (serine hydroxymethyltransferase, serine methylase) identified by sequence similarity; identified by match to PFAM protein family HMMPF00464 InterPro: Serine hydroxymethyltransferase (SHMT); High confidence in function and specificity YP_693897.1 ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence YP_693899.1 (rna polymerase sigma-e factor (sigma-24).) identified by sequence similarity; InterPro: Sigma factor ECF subfamily; Family membership YP_693902.1 SAM (and some other nucleotide) binding motif; High confidence in function and specificity YP_693903.1 (soluble pyridine nucleotide transhydrogenase) identified by sequencesimilarity; InterPro: FAD-dependent pyridine nucleotide-disulphide oxidoreductase belongs to the class-i of pyridine nucleotide- disulfide oxidoreductase family.; High confidence in function and specificity YP_693904.1 (conserved hypothetical protein YP_693905.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents YP_693906.1 identified by sequence similarity; InterPro: Alanine racemase catalytic activity: l-alanine = d-alanine. cofactor: pyridoxal phosphate (by similarity). pathway: d-alanine branch of peptidoglycan biosynthesis; first step.; High confidence in function and specificity YP_693907.1 (groP), (grpA) identified by match to TIGR protein family HMMTIGR00665; High confidence in function and specificity YP_693908.1 (ribosomal protein L9) identified by sequence similarity; InterPro: Ribosomal protein L9; High confidence in function and specificity YP_693909.1 (ribosomal protein S18) identified by sequencesimilarity; InterPro: Ribosomal protein S18; High confidence in function and specificity YP_693910.1 identified by match to PFAM protein family PF00436; High confidence in function and specificity YP_693911.1 (ribosomal protein S6) identified by sequencesimilarity; InterPro: Ribosomal protein S6; High confidence in function and specificity YP_693912.1 Family membership YP_693913.1 identified by sequencesimilarity; InterPro: VacB and RNase II family 3-5 exoribonuclease; High confidence in function and specificity YP_693914.1 predicted by Glimmer/Critica YP_693915.1 (multidrug efflux RND transporter ) identified by match to TIGR protein family HMMTIGR00915 YP_693916.1 conserved hypothetical protein, predicted phosphatase YP_693917.1 (adenylosuccinate synthetase) identified by sequencesimilarity; InterPro: Adenylosuccinate synthetase; High confidence in function and specificity YP_693918.1 identified by sequence similarity; belongs to class II aminoacyl-tRNA synthetases family as identified by match to TIGR protein family HMMTIGR00443; Function unclear YP_693919.1 predicted by Glimmer/Critica YP_693920.1 identified by match to PFAM protein family HMMPF01145; Specificity unclear YP_693921.1 identified by sequence similarity.; Family membership YP_693922.1 identified by sequence similarity; High confidence in function and specificity YP_693923.1 (hfg) identified by sequence similarity.; Family membership YP_693924.1 (tRNA delta(2)-isopentenylpyrophosphatetransferase) identified by sequencesimilarity; InterPro: tRNA isopentenyltransferase; High confidence in function and specificity YP_693925.1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex YP_693926.1 identified by sequencesimilarity; InterPro: Cell wall hydrolase/autolysin; High confidence in function and specificity YP_693927.1 (conserved hypothetical protein TIGR00150) identified by match to TIGR protein family HMMTIGR00150 InterPro: Uncharacterised P-loop hydrolase UPF0079 YP_693928.1 identified by match to PFAM protein family HMMPF01256 InterPro: Uncharacterized protein family UPF0031 YP_693929.1 identified by match to TIGR protein family HMMTIGR00276 InterPro: Fe_S cluster binding; Conserved hypothetical protein YP_693930.1 3'-5' exoribonuclease specific for small oligoribonuclotides YP_693931.1 EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity YP_693932.1 identified by sequence similarity InterPro: Rhodanese/cdc25 fold; High confidence in function and specificity YP_693933.1 identified by match to PFAM protein family HMMPF02666 InterPro: Phosphatidylserine decarboxylase; High confidence in function and specificity YP_693934.1 Alpha/beta hydrolase fold, PHA_synth_III_C: poly(R)-hydroxyalkanoic acid synthase, class III, PhaC subunit; High confidence in function and specificity YP_693935.1 heptosyltransferase II; identified by sequence similarity; InterPro: Glycosyltransferase family 9 Members of this family belong to glycosyltransferase family 9. Lipopolysaccharide is a major component of the outer leaflet of the outer membrane in Gram-negative bacteria. It is composed of three domains; lipid A, Core oligosaccharide and the O-antigen. All of these enzymes transfer heptose to the lipopolysaccharide core.; High confidence in function and specificity YP_693936.1 (dethiobiotin synthetase) identified by match to PFAM protein family HMMPF01656 InterPro: Cobyrinic acid ac-diamide synthase; High confidence in function and specificity YP_693937.1 (biotin biosynthesis protein BioC) identified by sequence similarity; Hypothetical protein YP_693938.1 identified by match to TIGR protein family HMMTIGR01738 InterPro: Alpha/beta hydrolase fold; High confidence in function and specificity YP_693939.1 identified by sequence similarity; InterPro: Aminotransferases class-I; High confidence in function and specificity YP_693940.1 (biotin synthetase) identified by sequencesimilarity; High confidence in function and specificity YP_693941.1 (competence protein ComF ) identified by sequence similarity YP_693942.1 Family membership YP_693943.1 identified by sequencesimilarity; High confidence in function and specificity YP_693945.1 4-alpha-hydroxytetrahydrobiopterin dehydratase activity; catalyzes the formation of (6R)-6-(L-erythro-1,2-dihydroxypropyl)-7, 8-dihydro-6H-pterin from (6R)-6-(L-erythro-1,2-dihydroxypropyl)-5,6,7, 8-tetrahydro-4a-hydroxypterin; functions in recycling tetrahydrobiopterin (BH4) in phenylalanine hydroxylase reaction YP_693947.1 identified by sequencesimilarity; InterPro: Uroporphyrinogen decarboxylase (URO-D); High confidence in function and specificity YP_693948.1 glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate YP_693949.1 catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate YP_693951.1 identified by sequence similarity; identified by match to PFAM protein family HMMPF01761 InterPro: 3-dehydroquinate synthase; High confidence in function and specificity YP_693952.1 identified by sequence similarity; identified by match to PFAM protein family HMMPF01202; InterPro: Shikimate kinase; High confidence in function and specificity YP_693953.1 InterPro: General (type II) secretion pathway (GSP) D protein; Hypothetical protein YP_693954.1 Hypothetical protein YP_693955.1 Hypothetical protein YP_693956.1 Hypothetical protein YP_693957.1 Hypothetical protein YP_693958.1 Penicillin-binding protein 1A (PBP-1a) (PBP1a),(Penicillin-insensitive transglycosylase),(Peptidoglycan TGase);(Penicillin-sensitive transpeptidase),(DD-transpeptidase)]. identified by sequence similarity; InterPro: Penicillin binding protein transpeptidase domain; High confidence in function and specificity YP_693959.1 identified by match to PFAM protein family HMMPF00390 InterPro: Malic enzymes; High confidence in function and specificity YP_693960.1 identified by match to PFAM protein family HMMPF01197 InterPro: Ribosomal protein L31; High confidence in function and specificity YP_693961.1 identified by sequencesimilarity; InterPro: DEAD/DEAH box helicase; High confidence in function and specificity YP_693962.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase YP_693964.1 heat shock protein involved in degradation of misfolded proteins YP_693965.1 heat shock protein involved in degradation of misfolded proteins YP_693966.1 (ubiquinone biosynthesis methyltransferase) identified by sequence similarity; InterPro: ubiE/COQ5 methyltransferase; Family membership YP_693968.1 (conserved hypothetical protein) identified by Glimmer2; InterPro: ABC1 family; High confidence in function and specificity YP_693969.1 catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribolsyl)-ATP in histidine biosynthesis YP_693970.1 High confidence in function and specificity YP_693971.1 Family membership YP_693972.1 identified by match to PFAM protein family HMMPF00902 InterPro: Uncharacterized protein family UPF0032; Family membership YP_693973.1 identified by match to TIGR protein family HMMTIGR01738 InterPro: Esterase/lipase/thioesterase family active site; Specificity unclear YP_693976.1 hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine YP_693977.1 identified by sequence similarity; InterPro: Alpha/beta hydrolase fold; High confidence in function and specificity YP_693978.1 predicted by Glimmer/Critica YP_693979.1 identified by sequencesimilarity; InterPro: Sigma-54 factor interaction domain; High confidence in function and specificity YP_693980.1 identified by match to PFAM protein family HMMPF02518 InterPro: Histidine kinase C-terminal; High confidence in function and specificity YP_693981.1 (conserved hypothetical protein) identified by sequencesimilarity YP_693982.1 (glutamine synthetase type I, glutamate-ammonia ligase) identified by sequence similarity; identified by match to TIGRFAM protein family HMMTIGR00653; High confidence in function and specificity YP_693984.1 identified by sequencesimilarity.; High confidence in function and specificity YP_693985.1 InterPro: Sulfatase YP_693987.1 identified by match to PFAM protein family HMMPF04093 YP_693988.1 identified by sequence similarity YP_693989.1 identified by match to TIGR protein family HMMTIGR01394 InterPro: GTP-binding elongation factor; High confidence in function and specificity YP_693990.1 (oxidoreductase aldo/keto reductase family) identified by match to TIGR protein family HMMTIGR01293 YP_693991.1 identified by match to TIGR protein family HMMTIGR00185 InterPro: RNA methyltransferase TrmH family group 2; Family membership YP_693992.1 identified by sequence similarity; InterPro: Bacterial protein export chaperone SecB; High confidence in function and specificity YP_693993.1 (glutaredoxin, ) identified by match to PFAM protein family HMMPF00462 InterPro: Glutaredoxin; High confidence in function and specificity YP_693994.1 (rhodanese domain protein, ) identified by similarity to PFAMB protein family PB095705 PB094266 PB093724 PB092780 PB092388 PB091758 PB086012 PB074034 PB071888 PB045826 PB027182 PB012820 PB012628 PB009308 PB006481; InterPro: Rhodanese/cdc25 fold; Family membership YP_693996.1 identified by match to PFAM protein family HMMPF03572 InterPro: Carboxyl-terminal protease; High confidence in function and specificity YP_693998.1 catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase YP_693999.1 (1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)met hylideneamino] imidazole-4-carboxamide isomerase, phosphoribosylformimino-5-aminoimidazolecarboxamide ribotide isomerase) identified by sequence similarity; identified by match to TIGRFAM protein family HMMTIGR00007 InterPro: Histidine biosynthesis protein; High confidence in function and specificity YP_694000.1 (glutamine amidotransferase, imidazole glycerol phosphate synthase subunit hisH) identified by sequence similarity; identified by match to PFAM protein family HMMPF00117 InterPro: Glutamine amidotransferase class-I; High confidence in function and specificity YP_694001.1 identified by sequence similarity; identified by match to PFAM protein family HMMPF00475 InterPro: Imidazoleglycerol-phosphate dehydratase; High confidence in function and specificity YP_694003.1 (sensor histidine kinase, ) identified by match to PFAM protein family HMMPF02518 InterPro: Histidine kinase C-terminal; Family membership YP_694005.1 identified by sequence similarity; InterPro: HhH-GPD; High confidence in function and specificity YP_694007.1 (transposase, ) identified by sequence similarity; High confidence in function and specificity YP_694008.1 P450, cytochrome p450 (conserved hypothetical protein) very GP:2588989; identified by sequencesimilarity; High confidence in function and specificity YP_694009.1 identified by sequence similarity YP_694010.1 catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate to form D,D-heptose-1,7-bisphosphate and catalyzes transfer of ADP to D-glycero-D-manno-heptose 1-phosphate forming ADP-D,D-heptose YP_694011.1 (permease and transmembrane protein, ); identify by sequence similarity to PFAM, PB096426 PB094699 PB074947 PB047492 PB044947 PB037484 PB001524; Conserved hypothetical protein YP_694012.1 (lipid A biosynthesis lauroyl acyltransferase) identified by sequence similarity; The bacterial lipid A biosynthesis protein, or lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase (EC 2.3.1.-), transfers myristate or laurate, activated on ACP, to the lipid IVA moiety of (KDO)2-(lauroyl)-lipid IVA during lipopolysaccharide core biosynthesis.; High confidence in function and specificity YP_694013.1 (permease and transmembrane protein, ); identify by sequence similarity to PFAM, PB096426 PB094699 PB074947 PB047492 PB044947 PB037484 PB001524; Conserved hypothetical protein YP_694014.1 identify by sequence similarity KDO kinase-like domain YP_694015.1 (yibd) (glycosyl transferase group 2 family protein) identified by match to PFAM protein family HMMPF00535; High confidence in function and specificity YP_694016.1 (rfaP) (Lipopolysaccharide core biosynthesis protein (WaaP)) identified by sequence similarity.; High confidence in function and specificity YP_694017.1 (rfag) (lipopolysaccharide core biosynthesis protein, glucosyltransferase family 1) identified by match to PFAM protein family HMMPF00534 InterPro: Glycosyl transferases group 1; High confidence in function and specificity YP_694018.1 (heptosyltransferase I); High confidence in function and specificity YP_694019.1 identified by sequence similarity.; Family membership YP_694020.1 (ADP-heptose--LPS heptosyltransferase II, ); identify by similarity to InterPro IPR002201 and PFAM protein family PF01075. InterPro IPR002201; Glyco_trans_9. lipopolysaccharide core biosynthesis.; High confidence in function and specificity YP_694021.1 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids YP_694022.1 identified by sequencesimilarity; High confidence in function and specificity YP_694023.1 (type II secretion system protein, ) identified by sequence similarity and match to PFAM protein family HMMPF00437 Type II traffic warden ATPase; Pectic enzymes secretion protein outE InterPro: Bacterial type II secretion system protein E; Family membership YP_694024.1 identify by sequence similarity YP_694025.1 (phosphate transporter, ) identified by match to PFAM protein family HMMPF01384 InterPro: Phosphate transporter family; High confidence in function and specificity YP_694026.2 catalyzes the formation of N-acetyl-L-glutamate from L-glutamate and acetyl-CoA in arginine biosynthesis YP_694032.1 (ilvD-2) identified by sequence similarity; identified by match to PFAM protein family HMMPF00920 InterPro: Dihydroxy-acid dehydratase; High confidence in function and specificity YP_694033.1 2-hydroxychromene-2-carboxylate isomerase identified by sequencesimilarity; InterPro: 2-hydroxychromene-2-carboxylate isomerase; High confidence in function and specificity YP_694034.1 identified by match to PFAM protein family HMMPF01124 YP_694035.1 oxidoreductase iron-sulfur-binding identified by match to PFAM protein family HMMPF00970; Family membership YP_694036.1 Function unclear YP_694037.1 (PqiB family protein) identified by sequence similarity; Family membership YP_694039.1 identified by sequence similarity; InterPro: TPR repeat; Hypothetical protein YP_694040.1 identified by sequence similarity; Hypothetical protein YP_694041.1 (uroporphyrinogen-III synthetase) identified by sequencesimilarity; InterPro: Uroporphyrinogen III synthase HEM4; Family membership YP_694042.1 transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis YP_694043.1 (Alginate biosynthesis regulatory protein AlgR) identified by sequence similarity; InterPro: Response regulator receiver domain Pfam N-terminus: response_rec, Response regulator receiver domain Pfam C-terminus: LytTr; LytTr DNA-binding domain; High confidence in function and specificity YP_694044.1 (two-component system sensor protein, alginate biosynthesis) identified by Glimmer2; High confidence in function and specificity YP_694045.1 catalyzes the formation of arginine from (N-L-arginino)succinate YP_694046.1 identified by sequence similarity; High confidence in function and specificity YP_694047.1 Similar to outer membrane lipoprotein,YifL (STY3613) YP_694048.1 identified by sequence similarity; identified by match to PFAM protein family HMMPF00278; High confidence in function and specificity YP_694049.1 (rhs-related protein) identified by sequencesimilarity; InterPro: Na+/H+ antiporter NhaC; High confidence in function and specificity YP_694050.1 (diamine acetyltransferase) (Spermidine/spermine N(1)-acetyltransferase) (SSAT) (Putrescine acetyltransferase) (Pfam: GNAT family) identified by match to TIGR protein family HMMTIGR01575 InterPro: GCN5-related N-acetyltransferase; High confidence in function and specificity YP_694051.1 (conserved hypothetical protein, presumably involved in catabolism of external DNA) identified by sequence similarity; Family membership YP_694052.1 identified by sequence similarity; identified by match to TIGRFAM protein family HMMTIGR00652 InterPro: Diaminopimelate epimerase; High confidence in function and specificity YP_694053.1 identified by sequence similarity YP_694054.1 identified by sequence similarity; InterPro: Phage integrase; High confidence in function and specificity YP_694055.1 (hydrolase, haloacid dehalogenase-like family, ) identified by match to TIGR protein family HMMTIGR01668 InterPro: Haloacid dehalogenase/epoxide hydrolase family; Family membership YP_694056.1 identified by match to PFAM protein family HMMPF04287 YP_694057.1 conserved hypothetical protein, distantly related to probable hemin degrading/transport factor Q56990 YP_694058.1 (Hemin uptake protein, COG4256, ); Family membership YP_694059.1 hypothetical protein, contains domain YP_694060.1 identified by match to PFAM protein family HMMPF00126 YP_694061.1 identified by sequence similarity. YP_694062.1 identified by sequencesimilarity; Family membership YP_694063.1 identified by match to PFAM protein family HMMPF00186; High confidence in function and specificity YP_694064.1 (thymidylate synthase; dTMP synthase) identified by sequence similarity; InterPro: Thymidylate synthase; High confidence in function and specificity YP_694065.1 (umpA) identified by match to TIGR protein family HMMTIGR00544 InterPro: Prolipoprotein diacylglyceryl transferase; High confidence in function and specificity YP_694066.1 identified by sequencesimilarity; InterPro: Domain of unknown function DUF81 YP_694067.1 identified by sequencesimilarity YP_694068.1 (phosphoenolpyruvate-protein phosphotransferasePtsP) identified by sequencesimilarity; InterPro: PEP-utilizing enzyme; High confidence in function and specificity YP_694069.1 (di)nucleoside polyphosphate hydrolase ) identified by sequencesimilarity; InterPro: NUDIX hydrolase; Specificity unclear YP_694071.1 (universal stress protein family) identified by match to PFAM protein family HMMPF00582 YP_694073.1 Copper-transporting P-type ATPase (EC 3.6.3.4).; High confidence in function and specificity YP_694074.1 predicted by Glimmer/Critica YP_694076.1 predicted metal-binding protein (conserved hypothetical protein) identified by match to PFAM protein family HMMPF04214 YP_694077.1 identified by match to PFAM protein family HMMPF01810; InterPro: Lysine exporter protein (LYSE/YGGA); Family membership YP_694079.1 (copper resistance protein A) identified by sequencesimilarity; InterPro: Multicopper oxidase type 1; High confidence in function and specificity YP_694080.1 (copB) (copper resistance protein B); High confidence in function and specificity YP_694081.1 identified by match to PFAM protein family HMMPF00484 InterPro: Prokaryotic-type carbonic anhydrase; High confidence in function and specificity YP_694082.1 identified by sequencesimilarity; InterPro: MoaA / nifB / pqqE family; Family membership YP_694083.1 identified by sequence similarity; InterPro: FKBP-type peptidyl-prolyl cis-trans isomerase (PPIase); High confidence in function and specificity YP_694084.1 identified by match to PFAM protein family HMMPF01177 InterPro: Glutamate racemase provides the (r)-glutamic acid required for cell wall biosynthesis (by similarity).; High confidence in function and specificity YP_694085.1 catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation YP_694086.1 (cob(I)yrinic acid a,c-diamide adenosyltransferase; ATP:corrinoid adenosyltransferase;) identified by sequencesimilarity; InterPro: ATP:corrinoid adenosyltransferase BtuR/CobO/CobP; High confidence in function and specificity YP_694087.1 Acid--ammonia (or amine) ligases (amide synthases) identified by sequencesimilarity; InterPro: Cobyrinic acid ac-diamide synthase; Specificity unclear YP_694088.1 Family membership YP_694089.1 Family membership YP_694090.1 identified by sequence similarity; InterPro: Periplasmic binding protein; Family membership YP_694091.1 identified by match to PFAM protein family HMMPF00593 InterPro: TonB-dependent receptor protein; Family membership YP_694094.1 (Cytochrome c551 peroxidase precursor (EC 1.11.1.5)) (Cytochrome c peroxidase); InterPro IPR000345; CytC_heme_BS. IPR004852; CytCP_MauG.; High confidence in function and specificity YP_694096.1 identified by sequence similarity; High confidence in function and specificity YP_694097.1 CobD; CbiD in Salmonella; converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group YP_694098.1 identified by sequencesimilarity; InterPro: Phosphoribosyltransferase family (DBI_PRT); High confidence in function and specificity YP_694099.1 (alpha-ribazole-5-phosphate phosphatase, ) identified by sequence similarity; InterPro: Phosphoglycerate mutase family; Family membership YP_694100.1 bifunctional cobalamin biosynthesis protein cobu [includes: cobinamide kinase; cobinamide phosphate guanylyltransferase].; High confidence in function and specificity YP_694101.1 identified by sequence similarity; IPR004624) Phosphonoacetate hydrolase PhnA is a novel carbon-phosphorus bond cleavage enzyme. The phnA gene is part of a large operon in Escherichia coli associated with alkylphosphonate uptake and carbon-phosphorus bond cleavage. PhnA is found in both gram positive and gram negative bacteria. Alignment; High confidence in function and specificity YP_694102.1 identified by sequence similarity; InterPro: Molybdenum cofactor biosynthesis protein; High confidence in function and specificity YP_694103.1 identified by sequencesimilarity; InterPro: Molybdenum cofactor biosynthesis protein; High confidence in function and specificity YP_694104.1 (cytochrome P450, ) identified by sequencesimilarity; InterPro: Cytochrome P450 enzyme; High confidence in function and specificity YP_694105.1 (conserved hypothetical protein; Mechanosensitive ion channel) identified by match to PFAM protein family HMMPF00924 Pfam: MS_channel YP_694106.1 identified by match to PFAM protein family HMMPF00753 InterPro: Metallo-beta-lactamase superfamily; Family membership YP_694107.1 identified by match to PFAM protein family HMMPF03596 YP_694108.1 identified by sequencesimilarity YP_694110.1 (conserved hypothetical protein, non-secretory ) TIGR00149; Pfam: UPF0047 Uncharacterised protein family UPF004 YP_694111.1 identified by sequencesimilarity; High confidence in function and specificity YP_694112.1 identified by Glimmer2; Pfam: DUF523, Protein of unknown function (DUF523) YP_694113.1 identified by sequence similarity; InterPro: Flavin-containing monooxygenase (FMO); Family membership YP_694114.1 (oxidoreductase, short chain dehydrogenase/reductase family) identified by match to TIGR protein family HMMTIGR01500 InterPro: Short-chain dehydrogenase/reductase (SDR) superfamily Pfam adh_short, short chain dehydrogenase; Family membership YP_694116.1 (hypothetical protein) YP_694117.1 identified by sequence similarity; InterPro: Rieske iron-sulfur protein 2Fe-2S subunit belongs to the bacterial ring-hydroxylating dioxygenase ferredoxin component family.; Family membership YP_694118.1 catalyzes the formation of agmatine from arginine in putrescine and spermidine biosynthesis YP_694119.1 catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine YP_694121.1 C-terminal fragment of 2-hydroxychromene carboxylate isomerase, identified by sequencesimilarity; High confidence in function and specificity YP_694122.1 identified by match to PFAM protein family HMMPF03466 InterPro: Bacterial regulatory protein LysR family; Family membership YP_694123.1 identified by match to TIGR protein family HMMTIGR00249; InterPro: Phosphoglycerate mutase family; Family membership YP_694124.1 identified by match to PFAM protein family HMMPF00106 InterPro: Short-chain dehydrogenase/reductase (SDR) superfamily; Family membership YP_694125.1 identified by sequence similarity; InterPro: mce related protein; Conserved hypothetical protein YP_694126.1 Function unclear YP_694128.1 identified by match to PFAM protein family HMMPF00271 InterPro: DEAD/DEAH box helicase; Family membership YP_694129.1 identified by sequencesimilarity YP_694130.1 conserved hypothetical protein, contains Esterase/lipase/thioesterase family active site (InterPro) YP_694131.1 truncated gene for fucokinase / gluconokinase / glycerokinase / xylulokinase family, key enzyme in the regulation of glycerol uptake and metabolism.; Function unclear YP_694132.1 identified by sequencesimilarity YP_694133.1 Required for efficient pilin antigenic variation YP_694134.1 (oxidoreductase aldo/keto reductase family) identified by match to TIGR protein family HMMTIGR01293 InterPro: Aldo/keto reductase family; Family membership YP_694135.1 haloallkane dehalogenase; belongs to the haloalkane dehalogenase family. subfamily 1.; High confidence in function and specificity YP_694137.1 identified by sequence similarity YP_694138.1 (transcriptional regulator, ) identified by match to PFAM protein family HMMPF00440 InterPro: Bacterial regulatory proteins TetR family HTH reporting nucleic acid binding motif; Family membership YP_694139.1 InterPro: Iron-containing alcohol dehydrogenase; Specificity unclear YP_694140.1 identified by sequencesimilarity; InterPro: ThiJ/PfpI family; Family membership YP_694141.1 (ubiquinol oxidase subunit II cyanideinsensitive) identified by sequence similarity; InterPro: Cytochrome bd ubiquinol oxidase subunit II catalytic activity: ubiquinol-8 + o(2) = ubiquinone-8 + h(2)o; High confidence in function and specificity YP_694142.1 (ubiquinol oxidase subunit I cyanide insensitive) identified by sequence similarity; InterPro: Cytochrome bd ubiquinol oxidase subunit I; High confidence in function and specificity YP_694143.1 predicted by Glimmer/Critica YP_694144.1 identified by match to PFAM protein family HMMPF02696 InterPro: Uncharacterized protein family UPF0061 YP_694145.1 glutathione S-transferase family protein; Family membership YP_694146.1 (metallo-beta-lactamase super family protein) identified by match to PFAM protein family HMMPF00753 InterPro: Metallo-beta-lactamase superfamily; Family membership YP_694147.1 identified by sequence similarity; InterPro: Bacterial regulatory protein LysR family; Family membership YP_694148.1 identified by match to PFAM protein family HMMPF00903 InterPro: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Conserved hypothetical protein YP_694150.1 (alkyl hydroperoxide reductase F subunit) identified by sequence similarity; InterPro: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; High confidence in function and specificity YP_694151.1 identified by sequence similarity; InterPro: Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; High confidence in function and specificity YP_694152.1 predicted by Glimmer/Critica. YP_694153.1 conserved hypothetical protein, signal transduction protein containing a membrane domain, an EAL and a GGDEF domain and PAS/PAC domain YP_694154.1 (monofunctional biosynthetic peptidoglycantransglycosylase) identified by sequence similarity; InterPro: Glycosyltransferase family 51; High confidence in function and specificity YP_694156.1 (glutamine amidotransferase class I) identified by match to TIGR protein family HMMTIGR00888 InterPro: Glutamine amidotransferase class-I; Family membership YP_694157.1 identified by sequencesimilarity; InterPro: HMG-CoA Lyase-like family; High confidence in function and specificity YP_694158.1 (transcriptional regulator, AsnC family, ) identified by match to PFAM protein family HMMPF01037 InterPro: Bacterial regulatory proteins AsnC family; Family membership YP_694160.1 (enoyl-CoA hydratase/isomerase family protein, ) identified by match to PFAM protein family HMMPF00378 InterPro: Enoyl-CoA hydratase/isomerase; High confidence in function and specificity YP_694161.1 predicted by Glimmer/Critica. YP_694162.1 (phosphoserine phosphatase, o-phosphoserine phosphohydrolase) identified by sequence similarity; identified by match to TIGRFAM protein family HMMTIGR00338; InterPro: Phosphoserine phosphatase SerB; High confidence in function and specificity YP_694163.1 identified by sequencesimilarity YP_694166.1 identified by match to TIGR protein family HMMTIGR00038 InterPro: Elongation factor P (EF-P); High confidence in function and specificity YP_694167.1 identified by sequencesimilarity; InterPro: tRNA synthetases class II (D K and N); High confidence in function and specificity YP_694168.1 predicted by Glimmer/Critica. YP_694169.1 identified by match to TIGR protein family HMMTIGR01738 InterPro: Alpha/beta hydrolase fold; Family membership YP_694170.1 identified by sequencesimilarity. InterPro: Bacterial regulatory proteins TetR family; Family membership YP_694171.1 predicted by Glimmer/Critica. YP_694172.1 FadI; fatty acid oxidation complex component beta; functions in a heterotetramer with FadJ; similar to FadA2B2 complex; functions in beta-oxidation of fatty acids during anaerobic growth YP_694173.1 functions in fatty acid oxidation; converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA YP_694174.1 (lipase/esterase family protein) identified by sequence similarity; InterPro: Esterase/lipase/thioesterase/carboxlesterase family active site; High confidence in function and specificity YP_694175.1 (InterPro: contains Esterase/lipase/thioesterase family active site, PS50187) YP_694176.1 identified by sequence similarity YP_694177.1 identified by sequence similarity; InterPro: Prokaryotic transcription elongation factor GreA/GreB; High confidence in function and specificity YP_694178.1 identified by sequencesimilarity; InterPro: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Family membership YP_694179.1 catalyzes the formation of porphobilinogen from 5-aminolevulinate YP_694180.1 catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate YP_694181.1 Region start changed from 2788442 to 2788409 (-33 bases) YP_694182.1 identified by match to TIGR protein family HMMTIGR00411 InterPro: Thioredoxin; High confidence in function and specificity YP_694183.1 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes YP_694185.1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase TIGR00148 identified by sequencesimilarity; InterPro: Protein of unknown function DUF117; Specificity unclear YP_694186.1 identified by match to TIGR protein family HMMTIGR01679 InterPro: FAD linked oxidase N-terminal; Family membership YP_694188.1 InterPro: Transposase IS204/IS1001/IS1096/IS1165 family; High confidence in function and specificity YP_694190.1 (Cation efflux system protein) identified by sequencesimilarity; InterPro: Cation efflux family; Family membership YP_694191.1 identified by match to PFAM protein family HMMPF04295 InterPro: Heavy metal efflux pump CzcA; Family membership YP_694192.1 identified by match to TIGR protein family HMMTIGR01730; Family membership YP_694193.1 identified by match to TIGR protein family HMMTIGR01730; Family membership YP_694194.1 (hypothetical protein) YP_694195.1 High confidence in function and specificity YP_694196.1 conserved hypothetical protein, identical to A.borkumensis_cds_2469 YP_694197.1 homologous to CzcD situated upstream, (>90A identity, 95 AA similarity); identified by sequencesimilarity; InterPro: Cation efflux family; Family membership YP_694198.1 Pfam: Domain of unknown function DUF, DUF204; Conserved hypothetical protein YP_694199.1 (conserved hypothetical protein TIGR00156) identified by match to PFAM protein family HMMPF04076 YP_694201.1 identified by sequence similarity; InterPro: TonB-dependent receptor protein; High confidence in function and specificity YP_694202.1 Family membership YP_694203.1 (alcohol dehydrogenase, zinc-containing) identified by match to TIGR protein family HMMTIGR01751; Pfam: ADH_zinc_N, Zinc-binding dehydrogenase; High confidence in function and specificity YP_694204.1 identified by sequencesimilarity YP_694205.1 (conserved hypothetical protein YP_694206.1 identified by sequence similarity; Interpro:; Family membership YP_694207.1 identified by sequence similarity; InterPro: TonB-dependent receptor protein; Family membership YP_694208.1 identified by Glimmer2; InterPro: S1 RNA binding domain YP_694209.1 (conserved hypothetical protein) identified by Glimmer2 YP_694212.1 identified by match to TIGR protein family HMMTIGR00530 InterPro: Phospholipid and glycerol acyltransferase (from motifs_6.msf); Family membership YP_694213.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling YP_694214.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling YP_694215.1 identified by Glimmer2; InterPro: Esterase/lipase/thioesterase family active site YP_694216.1 (icc protein) identified by sequence similarity; InterPro: DNA repair exonuclease; Function unclear YP_694217.1 (conserved hypothetical protein YP_694218.1 (ADP-ribose diphosphatase)(Adenosine diphosphoribose pyrophosphatase) (ADPR-PPase) (ADP-ribosephosphohydrolase) belongs to the nudix hydrolase family, nudf subfamily.; Family membership YP_694219.1 required for the synthesis of the hydromethylpyrimidine moiety of thiamine YP_694220.1 (outer membrane efflux protein TolC) belongs to the prtf family of secretion proteins. Pfam: Outer membrane efflux protein, OEP; Family membership YP_694221.1 (kdtA) identified by sequence similarity; High confidence in function and specificity YP_694222.1 (conserved hypothetical protein) YP_694223.1 identified by match to PFAM protein family HMMPF00248 InterPro: Aldo/keto reductase family; Family membership YP_694226.1 catalyzes the hydrolysis of allophanate YP_694227.1 predicted by Glimmer/Critica. YP_694228.1 (transcriptional regulator, ) identified by match to PFAM protein family HMMPF00392 InterPro: Bacterial regulatory proteins GntR family; Family membership YP_694229.1 (branched-chain amino acid ABC transporter, ); identify by sequence similarity.; Family membership YP_694230.1 (branched-chain amino acid ABC transporter permease protein ) identified by match to PFAM protein family HMMPF02653; Family membership YP_694231.1 (branched-chain amino acid ABC transporter permease protein ) identified by sequence similarity and by match to PFAM protein family HMMPF02653; InterPro: Binding-system dependent bacterial transporters (araH livH/limM families); Function unclear YP_694232.1 identified by match to PFAM protein family HMMPF00005 InterPro: ABC transporter; Specificity unclear YP_694233.1 identified by sequence similarity; identified by match to TIGR protein family HMMTIGR01187 InterPro: ABC transporter; Specificity unclear YP_694234.1 predicted by Glimmer/Critica YP_694235.1 (transporter bile acid/Na+ symporter family) identified by sequence similarity; InterPro: Sodium bile acid symporter; Family membership YP_694236.1 (cadA-1) (cadmium translocating P-type ATPase) identified by sequence similarity YP_694237.1 identified by sequencesimilarity; InterPro: Histidine kinase C-terminal; Family membership YP_694238.1 (transcription regulator, )identified by sequence similarity; InterPro: Response regulator receiver domain; Family membership YP_694239.1 identified by match to PFAM protein family HMMPF00072 InterPro: Response regulator receiver domain; Family membership YP_694240.1 sensor histidin kinase, contains PAS-fold, HisKA and HATPase_c domains; Conserved hypothetical protein YP_694242.1 (RND efflux transporter)(AcrB/AcrD/AcrF family protein) identified by match to PFAM protein family HMMPF03599 InterPro: Acriflavin resistance protein; Conserved hypothetical protein YP_694243.1 (RND transporter membrane fusion protein) identified by match to TIGR protein family HMMTIGR01730 InterPro: HlyD family secretion protein; High confidence in function and specificity YP_694244.1 (transcriptional regulator, ) identified by match to PFAM protein family HMMPF00440 InterPro: Bacterial regulatory proteins TetR family; Family membership YP_694245.1 predicted by Glimmer/Critica YP_694246.1 identified by sequence similarity. YP_694247.1 N-terminal fragment of a phosphoenolpyruvate-protein phosphotransferase; identified by sequence similarity to Pfam family protein PF00391, PF01590, PF02896 Interpro: belongs to the pep-utilizing enzymes family: IPR00593, IPR006318/IPR000121; Family membership YP_694248.1 identified by match to PFAM protein family HMMPF03602 InterPro: SAM (and some other nucleotide) binding motif YP_694249.1 Ammonium transporter, Ammonium Transporter Family, amt: ammonium transporter; High confidence in function and specificity YP_694250.1 identified by sequence similarity; identified by match to PFAM protein family HMMPF00543 InterPro: Nitrogen regulatory protein P-II; High confidence in function and specificity YP_694251.1 identified by sequencesimilarity YP_694252.1 (magnesium chelatase-related protein, ) identified by sequence similarity; InterPro: Mg chelatase-related protein; Family membership YP_694253.1 (acyl-CoA dehydrogenase, ) identified by sequencesimilarity; InterPro: Acyl-CoA dehydrogenase; High confidence in function and specificity YP_694254.1 (short-chain dehydrogenase/reductase, ) identified by sequencesimilarity; InterPro: Short-chain dehydrogenase/reductase (SDR) superfamily; High confidence in function and specificity YP_694255.1 (yfcd) identified by sequencesimilarity; InterPro: Isopentenyl-diphosphate delta-isomerase; Family membership YP_694256.1 (transcriptional regulator, ) identified by match to PFAM protein family HMMPF00165 and by sequence similarity to the arac/xyls family of transcriptional regulators. InterPro: AraC type helix-turn-helix; Family membership YP_694257.1 (Ribosomal small subunit pseudouridine synthase A), (16Spseudouridylate 516 synthase), (16S pseudouridine 516 synthase), (Uracilhydrolyase).(S4 domain protein) identified by match to PFAM protein family HMMPF01479 InterPro: Conserved hypothetical protein 93; High confidence in function and specificity YP_694258.1 identified by match to PFAM protein family HMMPF01443 InterPro: UvrD/REP helicase; High confidence in function and specificity YP_694259.1 (Cytochrome c5, ) identified by sequencesimilarity; Family membership YP_694260.1 (cytochrome c5) identified by sequence similarity; InterPro: Cytochrome c class I a monoheme c-type cytochrome. it is unreactive with cytochrome c reductase or oxidase.; High confidence in function and specificity YP_694261.1 identified by sequence similarity; InterPro: Histidine kinase C-terminal; Specificity unclear YP_694263.1 identified by match to TIGR protein family HMMTIGR01387 InterPro: Response regulator receiver domain; Specificity unclear YP_694264.1 (small multidrug resistance protein, ) identified by match to PFAM protein family HMMPF00893 InterPro: Integral membrane protein DUF7; Family membership YP_694265.1 (transcriptional regulator, ) identified by match to PFAM protein family HMMPF00165 InterPro: AraC type helix-turn-helix; Family membership YP_694266.1 (fatty acid desaturase, ) identified by sequencesimilarity; InterPro: Fatty acid desaturase type 2; High confidence in function and specificity YP_694267.1 identified by match to PFAM protein family HMMPF03977 shows similarity to uncharacterized iron-regulated membrane protein (DUF337).This is a family of uncharacterized iron-regulated membrane proteins.; Function unclear YP_694268.1 predicted by Glimmer/Critica YP_694269.1 predicted by Glimmer/Critica YP_694270.1 predicted by Glimmer/Critica YP_694271.1 identified by sequence similarity YP_694272.1 predicted by Glimmer/Critica YP_694273.1 (lip) (lipase) identified by sequencesimilarity; InterPro: Esterase/lipase/thioesterase family active site YP_694275.1 (O-acetylhomoserine sulfhydrylase, O-acetylhomoserine (thiol)-lyase, oah sulfhydrylase, homocysteine synthase) identified by sequence similarity; identified by match to PFAM protein family HMMPF01053; InterPro: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes; High confidence in function and specificity YP_694276.1 (enoyl-CoA hydratase/isomerase family protein) identified by match to PFAM protein family HMMPF00378 InterPro: Enoyl-CoA hydratase/isomerase; High confidence in function and specificity YP_694277.1 (CBS domain protein) identified by match to PFAM protein family HMMPF04290 InterPro: CBS domain CBS domains are small intracellular modules of unknown function. They are mostly found in 2 or four copies within a protein. wo CBS domains are found in inosine-monophosphate dehydrogenase from all species, however the CBS domains are not needed for activity. CBS domains are found attached to a wide range of other protein domains suggesting that CBS domains may play a regulatory role. The region containing the CBS domains in Cystathionine-beta synthase is involved in regulation by S-AdoMet.; Family membership YP_694278.1 predicted by Glimmer/Critica YP_694279.1 identify by sequence similarity; Function unclear YP_694281.1 NnrS protein. pfam05940, This family consists of several bacterial NnrS like proteins. NnrS is a heme-Cu protein and a member of the short-chain dehydrogenase family. Expression of nnrS is dependent on the transcriptional regulator NnrR, which also regulates expression of genes required for the reduction of nitrite to nitrous oxide, including nirK and nor. NnrS is a haem-and copper-containing membrane protein. Genes encoding orthologues of NnrS are sometimes but not always found in bacteria encoding nitrite and/or nitric oxide reductase YP_694282.1 predicted metal-dependent hydrolase YP_694283.1 predicted N6-adenine-specific methylase YP_694284.1 identified by match to PFAM protein family HMMPF00675 InterPro: Insulinase family (Peptidase family M16) YP_694285.1 identified by sequencesimilarity; Function unclear YP_694286.1 (signal recognition particle receptor FtsY) identified by sequencesimilarity; InterPro: Cell division transporter substrate-binding protein FtsY; High confidence in function and specificity YP_694287.1 (aapP) (general amino acid ABC transporter ATP-bindingprotein) identified by match to TIGR protein family HMMTIGR00968; High confidence in function and specificity YP_694288.1 (cell division ABC efflux transporter permeaseprotein FtsX) identified by sequencesimilarity; High confidence in function and specificity YP_694289.1 (htpR), (hin), (fam). , (Heat shock regulatory protein F33.4). identified by sequence similarity; InterPro: Sigma-70 factor family; High confidence in function and specificity YP_694290.1 identified by sequencesimilarity YP_694291.1 Region start changed from 2912636 to 2912648 (-12 bases) YP_694292.1 functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate YP_694293.1 (conserved hypothetical protein TIGR00091) identified by match to PFAM protein family HMMPF02390 InterPro: methyltransferase YP_694294.1 predicted by Glimmer/Critica) YP_694296.1 Catalyzes the conversion of acetyl-CoA and L-homoserine to CoA and O-acetyl-L-homoserine YP_694297.1 (methionine biosynthesis protein) identified by sequencesimilarity; High confidence in function and specificity YP_694298.1 identified by match to TIGR protein family HMMTIGR00042 InterPro: Ham1 family; Family membership YP_694299.1 identified by match to PFAM protein family HMMPF02639 InterPro: DUF188 YP_694300.1 (oxygen-independent coproporphyrinogen IIIoxidase ) identified by match to PFAM protein family HMMPF04055; Function unclear YP_694301.1 conserved hypothetical protein YP_694303.1 (FAPY-DNAglycosylase).identified by sequence similarity; InterPro: Formamidopyrimidine-DNA glycolase; High confidence in function and specificity YP_694304.1 (N-methylhydantoinase A, hydantoin utilization protein A) identified by sequence similarity; identified by mtach to PFAM protein family HMMPF01968 InterPro: Hydantoinase/oxoprolinase; High confidence in function and specificity YP_694305.1 (fatty acid desaturase family protein, ) identified by match to PFAM protein family HMMPF00487 InterPro: Fatty acid desaturase; High confidence in function and specificity YP_694306.1 (conserved hyphotetical protein) YP_694307.1 identified by sequence similarity and by match to PFAM protein family HMMPF01810; InterPro: Lysine exporter protein (LYSE/YGGA); Family membership YP_694308.1 identified by sequencesimilarity; InterPro: Integrase catalytic core; Family membership YP_694310.1 Hypothetical protein YP_694311.1 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; forms a heterodimer with subunit 1 to form the P protein YP_694312.1 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; forms a heterodimer with subunit 2 to form the P protein YP_694313.1 identified by sequence similarity; identified by match to PFAM protein family HMMPF01597 and TIGRFAM protein family HMMTIGR00527 InterPro: Glycine cleavage H-protein; High confidence in function and specificity YP_694314.1 (glycine cleavage system T protein, aminomethyltransferase) identified by sequence similarity; identified by match to TIGRFAM protein family HMMTIGR00528 InterPro: Glycine cleavage T-protein (aminomethyl transferase); High confidence in function and specificity YP_694316.1 (iron ABC transporter permease protein ) identified by sequence similarity; InterPro: Binding-protein-dependent transport systems inner membrane component; Family membership YP_694317.1 (iron ABC transporter periplasmic iron-bindingprotein ) identified by sequence similarity; InterPro: Bacterial extracellular solute-binding protein family 1; Family membership YP_694318.1 Family membership YP_694319.1 Family membership YP_694320.1 (aminopeptidase P II, xaa-pro aminopeptidase, x-pro aminopeptidase, aminoacylproline aminopeptidase) identified by sequence similarity; InterPro: metallopeptidase family M24; High confidence in function and specificity YP_694321.1 identified by sequencesimilarity YP_694324.1 5-formyltetrahydrofolate cyclo-ligase family protein identified by match to PFAM protein family HMMPF01812 InterPro: 5-formyltetrahydrofolate cyclo-ligase; Family membership YP_694325.1 (threonine dehydratase biosynthetic, threonine deaminase) identified by sequence similarity; identified by match to PFAM protein families HMMPF00291 and HMMPF00585; InterPro: Pyridoxal-5-phosphate-dependent enzymes beta family; High confidence in function and specificity YP_694326.1 identified by match to TIGR protein family HMMTIGR00021 InterPro: Ribose 5-phosphate isomerase; High confidence in function and specificity YP_694327.1 predicted by Glimmer/Critica YP_694328.1 identified by sequence similarity YP_694331.1 (conserved hypothetical protein) identified by sequencesimilarity YP_694332.1 (fructose-1,6-bisphosphate aldolase) identified by sequence similarity InterPro: Fructose-bisphosphate aldolase class-II; High confidence in function and specificity YP_694333.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway YP_694334.1 identified by sequence similarity; InterPro: Glyceraldehyde 3-phosphate dehydrogenase; High confidence in function and specificity YP_694335.1 identified by sequence similarity InterPro: Transketolase; Family membership YP_694336.1 transcriptional regulator ArsR family identified by match to PFAM protein family HMMPF01022 InterPro: SAM (and some other nucleotide) binding motif; Family membership YP_694337.1 catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase YP_694338.1 catalyzes the formation of L-homocysteine from S-adenosyl-L-homocysteine YP_694339.1 (5,10-methylenetetrahydrofolate reductase) identified by sequence similarity; identified by match to PFAM protein family HMMPF02219 and TIGRFAM protein family HMMTIGR00676; InterPro: Methylenetetrahydrofolate reductase; High confidence in function and specificity; deleted EC_number 1.7.99.5 YP_694341.1 (pyruvate kinase) identified by sequencesimilarity; InterPro: Pyruvate kinase family; High confidence in function and specificity YP_694343.1 (MATE efflux family protein, ) identified by match to PFAM protein family HMMPF04235 InterPro: Uncharacterized domain UPF0013; Family membership YP_694344.1 (hypothetical protein) predicted by Glimmer/Critica YP_694347.1 (hypothetical protein) predicted by Glimmer/Critica. YP_694348.1 identified by match to PFAM protein family HMMPF01594 InterPro: Domain of unknown function DUF20; Specificity unclear YP_694349.1 predicted Ca2+/Na+ antiporter; Conserved hypothetical protein YP_694350.1 (AcrB/C/D family cation/multidrug efflux pump; Transporter of the RND family of multidrug efflux pump) identified by match to PFAM protein family HMMPF03626 InterPro: Acriflavin resistance protein; Family membership YP_694351.1 Multidrug resistance protein mdtA precursor; Conserved hypothetical protein YP_694352.1 (peroxiredoxin family protein/glutaredoxin, ); identified by sequencesimilarity; InterPro: Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Family membership YP_694353.1 Conserved hypothetical protein YP_694354.1 (membrane protein, hemolysin III homolog, ); Function unclear YP_694355.1 (Transcriptional regulator, ArsR family, ) identified by match to PFAM protein family HMMPF01022 InterPro: Bacterial regulatory proteins ArsR family; High confidence in function and specificity YP_694356.1 identify by sequnece similarity. YP_694357.1 (hypothetical protein) YP_694358.1 glutathione peroxidase; High confidence in function and specificity YP_694359.1 identified by match to TIGR protein family HMMTIGR01382 InterPro: ThiJ/PfpI family YP_694360.1 dGTPase family type 3 subfamily, presumably hydrolyzes dGTP to deoxyguanosine and triphosphate YP_694361.1 identified by sequence similarity YP_694362.1 (ABC efflux transporter permease/ATP-bindingprotein ) identified by sequence similarity YP_694363.1 (hypothetical protein) YP_694364.1 (hypothetical protein); identified by sequence similarity. YP_694365.1 (hydrolase, alpha/beta hydrolase fold family, ) identified by match to TIGR protein family HMMTIGR01738 InterPro: Esterase/lipase/thioesterase family active site; Family membership YP_694367.1 Conserved hypothetical protein YP_694368.1 identified by match to PFAM protein family HMMPF03372 shows similarity to an endonuclease/Exonuclease/phosphatase family protein in P. syringae. This large family of proteins includes magnesium dependent endonucleases and a large number of phosphatases involved in intracellular signalling. YP_694369.1 identified by sequencesimilarity; InterPro: DSBA oxidoreductase; High confidence in function and specificity YP_694370.1 (cytochrome c4) identified by sequencesimilarity; InterPro: Cytochrome c class I; High confidence in function and specificity YP_694371.1 identified by sequencesimilarity; InterPro: Cytochrome c class I; Specificity unclear YP_694372.1 (engb) ; identify by sequence similarity; Hypothetical protein YP_694373.1 subunit G of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; in S. meliloti it is known to be involved specifically with K+ transport YP_694374.1 (Multisubunit Na+/H+ antiporter, MnhF subunit, ) identified by sequence similarity; Family membership YP_694375.1 subunit E of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; in S. meliloti it is known to be involved specifically with K+ transport YP_694376.1 ( cation efflux system protein, ); identifiedby sequence similarity; InterPro: NADH-Ubiquinone/plastoquinone (complex I) various chains; High confidence in function and specificity YP_694377.1 subunit C of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali YP_694378.1 subunit A of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; in S. meliloti it is known to be involved with K+ YP_694379.1 identified by sequencesimilarity; InterPro: Replicative DNA polymerase; High confidence in function and specificity YP_694380.1 Hypothetical protein YP_694381.1 (outer membrane ferric siderophore receptor) identified by sequence similarity; InterPro: OmpA-like transmembrane domain YP_694382.1 Family membership YP_694384.1 shows some similarity (ca. 30 ) to secreted lipases. YP_694385.1 identified by sequence similarity; InterPro: HMG-CoA Lyase-like family; High confidence in function and specificity YP_694386.1 identified by sequencesimilarity; InterPro: Domain of unknown function DUF9; Family membership YP_694387.1 (YGGT family protein) identified by match to PFAM protein family HMMPF04020 InterPro: YGGT family; Family membership YP_694388.1 identified by sequence similarity; identified by match to PFAM protein family HMMPF01089 and TIGRFAM protein family HMMTIGR00112 InterPro: Delta 1-pyrroline-5-carboxylate reductase; High confidence in function and specificity YP_694389.1 identified by sequence similarity; InterPro: hypothetical upf0001 protein in pilt-proc intergenic region YP_694390.1 identified by sequence similarity InterPro: Bacterial type II secretion system protein E; Function unclear YP_694391.1 identified by sequence similarity InterPro: Bacterial type II secretion system protein E; Function unclear YP_694397.1 arsenical resistance protein ArsH; (arsH; NADPH-dependent FMN reductase) (conserved hypothetical protein); identified by sequencesimilarity YP_694398.1 InterPro: Sodium bile acid symporter; Conserved hypothetical protein YP_694399.1 identified by sequence similarity; InterPro: Low molecular weight phosphotyrosine protein phosphatase; High confidence in function and specificity YP_694400.1 identified by sequence similarity; InterPro: Bacterial regulatory proteins ArsR family; Specificity unclear YP_694401.1 (phosphate transport system regulatory proteinPhoU) identified by sequence similarity; High confidence in function and specificity YP_694402.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation YP_694403.1 identified by sequence similarity; InterPro: Binding-protein-dependent transport systems inner membrane component; High confidence in function and specificity YP_694404.1 identified by sequence similarity; InterPro: Binding-protein-dependent transport systems inner membrane component; High confidence in function and specificity YP_694405.1 (phosphate ABC transporter periplasmicphosphate-binding protein) identified by sequencesimilarity; InterPro: Phosphate-binding protein; High confidence in function and specificity YP_694406.1 TRAP-type sodium-dependent glutamate permease integral membrane protein (small) Pfam: Tripartite ATP-independent periplasmic transporters, DctQ component TMHMM: reporting 4 transmembrane helices; High confidence in function and specificity YP_694407.1 TRAP-type sodium-dependent glutamate permease integral membrane protein (large). identified by sequence similarity; SignalP: reporting signal peptide TMHMM: predicting 12 transmembrane helices; High confidence in function and specificity YP_694408.1 (long-chain acyl-CoA thioester hydrolase family protein, ) identified by match to PFAM protein family HMMPF01662 InterPro: long-chain acyl-CoA thioester hydrolase; High confidence in function and specificity YP_694409.1 TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component. Pfam: Extracellular solute-binding protein, family 7. This family of proteins are involved in binding extracellular solutes for transport across the bacterial cytoplasmic membrane. This family includes biochemically well-characterised DctP, periplasmic dicarboxylate (malate, fumarate, succinate) binding receptor.; High confidence in function and specificity YP_694410.1 identified by match to PFAM protein family HMMPF03711 InterPro: UvrD/REP helicase; High confidence in function and specificity YP_694411.1 identified by match to PFAM protein family HMMPF03466 InterPro: Domain of unknown function 2; Function unclear YP_694414.1 identified by sequencesimilarity; InterPro: Uncharacterized protein family UPF0003 YP_694415.1 (hypothetical protein) YP_694416.1 (oxidoreductase, ) identified by sequence similarity; InterPro: Short-chain dehydrogenase/reductase (SDR) superfamily; High confidence in function and specificity YP_694419.1 Phosphatidylserine/phosphatidylglycerophosphate/ cardiolipin synthases and related enzymes identified by sequence similarity; Family membership YP_694420.1 identified by match to PFAM protein family HMMPF04076 YP_694421.1 (cpdB) (2',3'-cyclic-nucleotide 2'-phosphodiesterase precursor (5`-nucleotidase)) identified by sequence similarity; InterPro: 5-Nucleotidase; Family membership YP_694422.1 catalyzes the formation of a phosphodiester at the site of a single-strand break in duplex DNA YP_694423.1 identified by match to PFAM protein family HMMPF01625 InterPro: Peptide methionine sulfoxide reductase; High confidence in function and specificity YP_694424.1 identified by match to PFAM protein family HMMPF01810 YP_694425.1 (membrane protein ) identified by sequence similarity; na(+)/h(+) antiporter (sodium/proton antiporter) (sodium/hydrogen antiporter); Hypothetical protein YP_694426.1 (alkB1GHJ positive regulator) identified by sequence similarity; InterPro: Bacterial regulatory protein LuxR family. Member of the MalT subfamily o f the LuxR family.; High confidence in function and specificity YP_694427.1 (alkane 1-monooxygenase, integral membrane non-heme iron monooxygenase); High confidence in function and specificity YP_694428.1 alkG rubredoxin identified by sequencesimilarity InterPro: Rubredoxin Rubredoxin-type Fe(Cys)4 protein involved in the hydrocarbon hydroxylating system, which transfers electrons from nadh to rubredoxin reductase and then through rubredoxin to alkane 1 monooxygenase; High confidence in function and specificity YP_694429.1 (aldehyde dehydrogenase family protein) identified by match to TIGR protein family HMMTIGR01722 InterPro: Aldehyde dehydrogenase family; High confidence in function and specificity YP_694430.1 identified by sequence similarity; identified by match to PFAM protein families HMMPF00732 and HMMPF05199; InterPro: Glucose-methanol-choline (GMC) oxidoreductase; High confidence in function and specificity YP_694432.1 (ribF) (riboflavin biosynthesis protein RibF) identified by sequence similarity; Hypothetical protein YP_694434.1 identified by match to PFAM protein family HMMPF00005 YP_694435.1 identified by sequence similarity.; High confidence in function and specificity YP_694436.1 identified by sequence similarity; InterPro: UreF; High confidence in function and specificity YP_694437.1 identified by sequence similarity; Family membership YP_694438.1 identified by sequence similarity; InterPro: UreE urease accessory protein; High confidence in function and specificity YP_694439.1 ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureC (alpha) and 3 ureAB (gamma/beta) subunits YP_694440.1 (urease beta subunit, urea amidohydrolase) identified by sequence similarity; identified by match to PFAM protein family HMMPF00699 and TIGRFAM protein family HMMTIGR00192 InterPro: Urease beta subunit; High confidence in function and specificity YP_694441.1 (urease gamma subunit, urea amidohydrolase) identified by sequence similarity; identified by match to PFAM protein family HMMPF00547 and TIGRFAM protein family HMMTIGR00193 InterPro: Urease gamma subunit; High confidence in function and specificity YP_694442.1 identified by sequence similarity; InterPro: UreD urease accessory protein; High confidence in function and specificity YP_694443.1 (glucosamine--fructose-6-phosphateaminotransferase isomerizing) identified by match to TIGR protein family HMMTIGR01135 InterPro: Glutamine amidotransferase class-II; High confidence in function and specificity YP_694444.1 Bifunctional glmU protein [Includes: UDP-N-acetylglucosaminepyrophosphorylase (EC 2.7.7.23) (N-acetylglucosamine-1-phosphateuridyltransferase); Glucosamine-1-phosphate N-acetyltransferase(EC 2.3.1.57)]. (UDP-N-acetylglucosamine pyrophosphorylase) identified by match to TIGR protein family HMMTIGR01173 InterPro: ADP-glucose pyrophosphorylase; High confidence in function and specificity YP_694445.1 (ATP synthase F1 epsilon subunit) identified by sequencesimilarity; InterPro: ATP synthase Delta/Epsilon chain catalytic reaction: atp + h(2)o + h(+)(in) = adp + phosphate + h(+)(out); High confidence in function and specificity YP_694446.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit YP_694447.1 (ATP synthase F1 gamma subunit) identified by match to PFAM protein family HMMPF00231 InterPro: ATP synthase gamma subunit; High confidence in function and specificity YP_694448.1 (ATP synthase F1 alpha subunit) identified by sequence similarity; InterPro: ATP synthase alpha and beta subunit central region; High confidence in function and specificity YP_694449.1 (ATP synthase F1 delta subunit) identified by sequence similarity; Function unclear YP_694450.1 identified by sequencesimilarity; InterPro: ATP synthase B/B CF(0); Function unclear YP_694451.1 (ATP synthase F0 C subunit) identified by match to TIGR protein family HMMTIGR01260 InterPro: ATP synthase subunit C; High confidence in function and specificity YP_694452.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0 YP_694453.1 (ATP synthase I subunit) identified by sequence similarity; Family membership YP_694454.1 identified by match to PFAM protein family HMMPF02195 InterPro: ParB-like partition protein; High confidence in function and specificity YP_694455.1 (ParA family ATPase) identified by sequencesimilarity; InterPro: ParA family ATPase; Family membership YP_694456.1 (glucose-inhibited division protein B; Methyltransferase gidB) identified by match to TIGR protein family HMMTIGR00138; High confidence in function and specificity YP_694457.1 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs YP_694458.1 (sodium/hydrogen exchanger family protein) identified by match to PFAM protein family HMMPF03471 InterPro: Na+/H+ exchanger; Family membership YP_694459.1 (acyl-CoA dehydrogenase family protein; ) identified by match to PFAM protein family HMMPF00441; Family membership YP_694461.1 Catalyzes the first step in the glyoxalate cycle, which converts lipids to carbohydrates YP_694462.1 acyltransferase, homologous to ABO_1804, AtfA2 and to the ACIAD0832, wax ester synthase/ diacylglycerol acyltransferase of Acinetobacter sp. AP1; High confidence in function and specificity YP_694463.1 identified by sequence similarity; InterPro: conserved hypothetical protein (UPF0010_DUF) YP_694464.1 cold-shock protein CspG identified by sequence similarity; InterPro: Cold-shock DNA-binding domain; Family membership YP_694465.1 identified by match to PFAM protein family HMMPF01863 InterPro: Protein of unknown function DUF45 YP_694466.1 identified by sequence similarity; InterPro: Acriflavin resistance protein The E.coli acrA and acrB genes encode a multi-drug efflux system that isbelieved to protect the bacterium against hydrophobic inhibitors [MEDLINE:94012493]. Members of this family are integral membrane proteins some of which are involved in drug resistance. Proteins which belong to this family (AcrB/AcrD/AcrF family protein) include the P.aeruginosa multidrug resistance protein mexB, A.eutrophus cation efflux system protein czcA, and various R.meliloti nodulation proteins.; Family membership YP_694467.1 (RND efflux membrane fusion protein, ); identify by sequence similarity, .; Family membership YP_694468.1 identified by match to TIGR protein family HMMTIGR01734 InterPro: AMP-dependent synthetase and ligase; High confidence in function and specificity YP_694469.1 class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle YP_694470.1 transcriptional regulator, TetR family; Family membership YP_694471.1 identified by match to TIGR protein family HMMTIGR00778; Family membership YP_694472.1 (trmE, thdF) (tRNA modification GTPase, previously known as thiophene and furan oxidation protein ThdF) identified by match to PFAM protein family HMMPF04183 InterPro: tRNA modification GTPase TrmE; High confidence in function and specificity YP_694473.1 (inner membrane protein 60 kDa, ) identified by sequencesimilarity; InterPro: 60Kd inner membrane protein; Family membership YP_694474.1 (ribonuclease P, protein component) identified by sequence similarity; InterPro: Bacterial ribonuclease P protein; High confidence in function and specificity YP_694475.1 identified by match to PFAM protein family HMMPF00468 InterPro: Ribosomal protein L34; High confidence in function and specificity