-- dump date 20140618_191331 -- class Genbank::CDS -- table cds -- table main -- field 1 id -- field 2 GI -- field 3 GeneID -- field 4 chrom_position -- field 5 chromosome -- field 6 codon_start -- field 7 contig -- field 8 description -- field 9 end_pos -- field 10 gene -- field 11 gene_id -- field 12 name -- field 13 organism -- field 14 product -- field 15 protein_id -- field 16 start_pos -- field 17 strand -- field 18 taxid -- field 19 type -- header -- id GI GeneID chrom_position chromosome codon_start contig description end_pos gene gene_id name organism product protein_id start_pos strand taxid type YP_008731343.1 556562918 17449143 1..1881 1 NC_022657.1 COG0593 ATPase involved in DNA replication initiation; putative chromosomal replication initiator protein 1881 17449143 AFR_00005 Actinoplanes friuliensis DSM 7358 putative chromosomal replication initiator protein YP_008731343.1 1 D 1246995 CDS YP_008731344.1 556562919 17440637 4900..6033 1 NC_022657.1 COG0592 DNA polymerase sliding clamp subunit (PCNA homolog); DNA polymerase III subunit beta 6033 17440637 AFR_00010 Actinoplanes friuliensis DSM 7358 DNA polymerase III subunit beta YP_008731344.1 4900 D 1246995 CDS YP_008731345.1 556562920 17449142 6071..6943 1 NC_022657.1 COG1023 Predicted 6-phosphogluconate dehydrogenase; 6-phosphogluconate dehydrogenase-like protein 6943 17449142 AFR_00015 Actinoplanes friuliensis DSM 7358 6-phosphogluconate dehydrogenase-like protein YP_008731345.1 6071 D 1246995 CDS YP_008731346.1 556562921 17440638 6947..8074 1 NC_022657.1 COG1195 Recombinational DNA repair ATPase (RecF pathway); recombination protein F 8074 recF 17440638 recF Actinoplanes friuliensis DSM 7358 recombination protein F YP_008731346.1 6947 D 1246995 CDS YP_008731347.1 556562922 17440639 8067..8627 1 NC_022657.1 COG5512 Zn-ribbon-containing, possibly RNA-binding protein and truncated derivatives; hypothetical protein 8627 17440639 AFR_00025 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731347.1 8067 D 1246995 CDS YP_008731348.1 556562923 17440640 8776..9117 1 NC_022657.1 hypothetical protein 9117 17440640 AFR_00030 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731348.1 8776 D 1246995 CDS YP_008731349.1 556562924 17440641 complement(9125..9691) 1 NC_022657.1 hypothetical protein 9691 17440641 AFR_00035 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731349.1 9125 R 1246995 CDS YP_008731350.1 556562925 17440642 10231..12183 1 NC_022657.1 COG0187 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit; DNA gyrase subunit B 12183 gyrB 17440642 gyrB Actinoplanes friuliensis DSM 7358 DNA gyrase subunit B YP_008731350.1 10231 D 1246995 CDS YP_008731351.1 556562926 17440643 12381..14834 1 NC_022657.1 COG0188 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit; DNA gyrase subunit A 14834 17440643 AFR_00045 Actinoplanes friuliensis DSM 7358 DNA gyrase subunit A YP_008731351.1 12381 D 1246995 CDS YP_008731352.1 556562927 17440644 14838..15725 1 NC_022657.1 hypothetical protein 15725 17440644 AFR_00050 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731352.1 14838 D 1246995 CDS YP_008731353.1 556562928 17440646 15940..16068 1 NC_022657.1 hypothetical protein 16068 17440646 AFR_00055 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731353.1 15940 D 1246995 CDS YP_008731354.1 556562929 17440648 complement(16215..16703) 1 NC_022657.1 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins; GCN5-related N-acetyltransferase 16703 17440648 AFR_00060 Actinoplanes friuliensis DSM 7358 GCN5-related N-acetyltransferase YP_008731354.1 16215 R 1246995 CDS YP_008731355.1 556562930 17440649 16987..17529 1 NC_022657.1 excisionase family DNA binding domain-containing protein 17529 17440649 AFR_00065 Actinoplanes friuliensis DSM 7358 excisionase family DNA binding domain-containing protein YP_008731355.1 16987 D 1246995 CDS YP_008731356.1 556562931 17440650 17637..18920 1 NC_022657.1 COG2230 Cyclopropane fatty acid synthase and related methyltransferases; putative cyclopropane fatty acid synthase 18920 17440650 AFR_00070 Actinoplanes friuliensis DSM 7358 putative cyclopropane fatty acid synthase YP_008731356.1 17637 D 1246995 CDS YP_008731357.1 556562932 17440651 19100..19462 1 NC_022657.1 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; RNA pyrophosphohydrolase 19462 17440651 AFR_00075 Actinoplanes friuliensis DSM 7358 RNA pyrophosphohydrolase YP_008731357.1 19100 D 1246995 CDS YP_008731358.1 556562933 17440652 complement(19496..19915) 1 NC_022657.1 hypothetical protein 19915 17440652 AFR_00080 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731358.1 19496 R 1246995 CDS YP_008731359.1 556562934 17440653 20005..20556 1 NC_022657.1 COG2606 Uncharacterized conserved protein; hypothetical protein 20556 17440653 AFR_00085 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731359.1 20005 D 1246995 CDS YP_008731360.1 556562935 17440654 20661..21182 1 NC_022657.1 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; acetyltransferase 21182 17440654 AFR_00090 Actinoplanes friuliensis DSM 7358 acetyltransferase YP_008731360.1 20661 D 1246995 CDS YP_008731361.1 556562936 17440655 complement(21199..21840) 1 NC_022657.1 COG2761 Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis; putative protein dithiol-disulfide isomerase 21840 17440655 AFR_00095 Actinoplanes friuliensis DSM 7358 putative protein dithiol-disulfide isomerase YP_008731361.1 21199 R 1246995 CDS YP_008731362.1 556562937 17440656 complement(21837..22253) 1 NC_022657.1 COG2166 SufE protein probably involved in Fe-S center assembly; Cysteine desulfuration protein sufE 22253 17440656 AFR_00100 Actinoplanes friuliensis DSM 7358 Cysteine desulfuration protein sufE YP_008731362.1 21837 R 1246995 CDS YP_008731363.1 556562938 17440657 complement(22287..22652) 1 NC_022657.1 COG0517 FOG: CBS domain; hypothetical protein 22652 17440657 AFR_00105 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731363.1 22287 R 1246995 CDS YP_008731364.1 556562939 17440658 complement(22718..24439) 1 NC_022657.1 COG0442 Prolyl-tRNA synthetase; prolyl-tRNA ligase 24439 17440658 AFR_00110 Actinoplanes friuliensis DSM 7358 prolyl-tRNA ligase YP_008731364.1 22718 R 1246995 CDS YP_008731365.1 556562940 17440659 24589..25362 1 NC_022657.1 COG2755 Lysophospholipase L1 and related esterases; putative GDSL-like lipase/acylhydrolase 25362 17440659 AFR_00115 Actinoplanes friuliensis DSM 7358 putative GDSL-like lipase/acylhydrolase YP_008731365.1 24589 D 1246995 CDS YP_008731366.1 556562941 17440660 25368..26267 1 NC_022657.1 COG2897 Rhodanese-related sulfurtransferase; putative thiosulfate sulfurtransferase 26267 17440660 AFR_00120 Actinoplanes friuliensis DSM 7358 putative thiosulfate sulfurtransferase YP_008731366.1 25368 D 1246995 CDS YP_008731367.1 556562942 17440661 26356..26928 1 NC_022657.1 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; ECF subfamily RNA polymerase sigma-24 subunit 26928 17440661 AFR_00125 Actinoplanes friuliensis DSM 7358 ECF subfamily RNA polymerase sigma-24 subunit YP_008731367.1 26356 D 1246995 CDS YP_008731368.1 556562943 17440662 26946..27764 1 NC_022657.1 zinc-finger family protein 27764 17440662 AFR_00130 Actinoplanes friuliensis DSM 7358 zinc-finger family protein YP_008731368.1 26946 D 1246995 CDS YP_008731369.1 556562944 17440663 27761..28618 1 NC_022657.1 COG1131 ABC-type multidrug transport system, ATPase component; ABC transporter 28618 17440663 AFR_00135 Actinoplanes friuliensis DSM 7358 ABC transporter YP_008731369.1 27761 D 1246995 CDS YP_008731370.1 556562945 17440664 28615..30114 1 NC_022657.1 hypothetical protein 30114 17440664 AFR_00140 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731370.1 28615 D 1246995 CDS YP_008731371.1 556562946 17440665 30153..30767 1 NC_022657.1 hypothetical protein 30767 17440665 AFR_00145 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731371.1 30153 D 1246995 CDS YP_008731372.1 556562947 17440666 30779..31312 1 NC_022657.1 COG4767 Glycopeptide antibiotics resistance protein; VanZ family protein 31312 17440666 AFR_00150 Actinoplanes friuliensis DSM 7358 VanZ family protein YP_008731372.1 30779 D 1246995 CDS YP_008731373.1 556562948 17440667 31350..33110 1 NC_022657.1 COG0326 Molecular chaperone, HSP90 family; heat shock protein 90 33110 17440667 AFR_00155 Actinoplanes friuliensis DSM 7358 heat shock protein 90 YP_008731373.1 31350 D 1246995 CDS YP_008731374.1 556562949 17440668 33107..35965 1 NC_022657.1 hypothetical protein 35965 17440668 AFR_00160 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731374.1 33107 D 1246995 CDS YP_008731375.1 556562950 17440669 36018..36620 1 NC_022657.1 COG1309 Transcriptional regulator; HTH-type transcriptional regulator betI 36620 17440669 AFR_00165 Actinoplanes friuliensis DSM 7358 HTH-type transcriptional regulator betI YP_008731375.1 36018 D 1246995 CDS YP_008731376.1 556562951 17440670 36818..38182 1 NC_022657.1 COG0439 Biotin carboxylase; carbamoyl-phosphate synthase subunit L 38182 17440670 AFR_00170 Actinoplanes friuliensis DSM 7358 carbamoyl-phosphate synthase subunit L YP_008731376.1 36818 D 1246995 CDS YP_008731377.1 556562952 17440671 38187..39068 1 NC_022657.1 COG0119 Isopropylmalate/homocitrate/citramalate synthases; putative hydroxymethylglutaryl-CoA lyase 39068 17440671 AFR_00175 Actinoplanes friuliensis DSM 7358 putative hydroxymethylglutaryl-CoA lyase YP_008731377.1 38187 D 1246995 CDS YP_008731378.1 556562953 17440672 39244..40302 1 NC_022657.1 COG3839 ABC-type sugar transport systems, ATPase components; Polycystic kidney disease protein 1-like 3 40302 17440672 AFR_00180 Actinoplanes friuliensis DSM 7358 Polycystic kidney disease protein 1-like 3 YP_008731378.1 39244 D 1246995 CDS YP_008731379.1 556562954 17440673 40587..41882 1 NC_022657.1 hypothetical protein 41882 17440673 AFR_00185 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731379.1 40587 D 1246995 CDS YP_008731380.1 556562955 17440674 42102..43628 1 NC_022657.1 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta); putative acyl-CoA carboxylase subunit beta 43628 17440674 AFR_00190 Actinoplanes friuliensis DSM 7358 putative acyl-CoA carboxylase subunit beta YP_008731380.1 42102 D 1246995 CDS YP_008731381.1 556562956 17440675 43642..44799 1 NC_022657.1 COG1960 Acyl-CoA dehydrogenases; putative acyl-CoA dehydrogenase 44799 17440675 AFR_00195 Actinoplanes friuliensis DSM 7358 putative acyl-CoA dehydrogenase YP_008731381.1 43642 D 1246995 CDS YP_008731382.1 556562957 17440676 44913..47402 1 NC_022657.1 COG1396 Predicted transcriptional regulators; helix-turn-helix domain-containing protein 47402 17440676 AFR_00200 Actinoplanes friuliensis DSM 7358 helix-turn-helix domain-containing protein YP_008731382.1 44913 D 1246995 CDS YP_008731383.1 556562958 17440677 complement(47673..48167) 1 NC_022657.1 COG1846 Transcriptional regulators; putative MarR-family transcriptional regulator 48167 17440677 AFR_00205 Actinoplanes friuliensis DSM 7358 putative MarR-family transcriptional regulator YP_008731383.1 47673 R 1246995 CDS YP_008731384.1 556562959 17440678 48271..48849 1 NC_022657.1 COG2353 Uncharacterized conserved protein; hypothetical protein 48849 17440678 AFR_00210 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731384.1 48271 D 1246995 CDS YP_008731385.1 556562960 17440679 49057..50532 1 NC_022657.1 hypothetical protein 50532 17440679 AFR_00215 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731385.1 49057 D 1246995 CDS YP_008731386.1 556562961 17440680 complement(50560..52413) 1 NC_022657.1 hypothetical protein 52413 17440680 AFR_00220 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731386.1 50560 R 1246995 CDS YP_008731387.1 556562962 17440681 52520..53359 1 NC_022657.1 COG2815 Uncharacterized protein conserved in bacteria; hypothetical protein 53359 17440681 AFR_00225 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731387.1 52520 D 1246995 CDS YP_008731388.1 556562963 17440682 complement(53369..53638) 1 NC_022657.1 hypothetical protein 53638 17440682 AFR_00230 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731388.1 53369 R 1246995 CDS YP_008731389.1 556562964 17440683 54177..54980 1 NC_022657.1 helix-turn-helix domain-containing protein 54980 17440683 AFR_00235 Actinoplanes friuliensis DSM 7358 helix-turn-helix domain-containing protein YP_008731389.1 54177 D 1246995 CDS YP_008731390.1 556562965 17440684 54944..55168 1 NC_022657.1 hypothetical protein 55168 17440684 AFR_00240 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731390.1 54944 D 1246995 CDS YP_008731391.1 556562966 17440685 55383..55835 1 NC_022657.1 hypothetical protein 55835 17440685 AFR_00245 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731391.1 55383 D 1246995 CDS YP_008731392.1 556562967 17440686 complement(55843..56523) 1 NC_022657.1 hypothetical protein 56523 17440686 AFR_00250 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731392.1 55843 R 1246995 CDS YP_008731393.1 556562968 17440687 complement(56805..57626) 1 NC_022657.1 COG1922 Teichoic acid biosynthesis proteins; putative glycosyltransferase 57626 17440687 AFR_00255 Actinoplanes friuliensis DSM 7358 putative glycosyltransferase YP_008731393.1 56805 R 1246995 CDS YP_008731394.1 556562969 17440688 complement(57608..58681) 1 NC_022657.1 COG0451 Nucleoside-diphosphate-sugar epimerases; NAD-dependent epimerase/dehydratase 58681 17440688 AFR_00260 Actinoplanes friuliensis DSM 7358 NAD-dependent epimerase/dehydratase YP_008731394.1 57608 R 1246995 CDS YP_008731395.1 556562970 17440690 59222..59980 1 NC_022657.1 COG1716 FOG: FHA domain; hypothetical protein 59980 17440690 AFR_00265 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731395.1 59222 D 1246995 CDS YP_008731396.1 556562971 17440691 59986..60468 1 NC_022657.1 COG1716 FOG: FHA domain; hypothetical protein 60468 17440691 AFR_00270 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731396.1 59986 D 1246995 CDS YP_008731397.1 556562972 17440692 60465..61892 1 NC_022657.1 COG0631 Serine/threonine protein phosphatase; protein phosphatase 61892 17440692 AFR_00275 Actinoplanes friuliensis DSM 7358 protein phosphatase YP_008731397.1 60465 D 1246995 CDS YP_008731398.1 556562973 17440693 61973..63424 1 NC_022657.1 COG0772 Bacterial cell division membrane protein; putative FtsW/RodA/SpoVE-family cell cycle protein 63424 17440693 AFR_00280 Actinoplanes friuliensis DSM 7358 putative FtsW/RodA/SpoVE-family cell cycle protein YP_008731398.1 61973 D 1246995 CDS YP_008731399.1 556562974 17440694 63421..64926 1 NC_022657.1 COG0768 Cell division protein FtsI/penicillin-binding protein 2; putative penicillin-binding protein 64926 17440694 AFR_00285 Actinoplanes friuliensis DSM 7358 putative penicillin-binding protein YP_008731399.1 63421 D 1246995 CDS YP_008731400.1 556562975 17440695 64928..66316 1 NC_022657.1 COG0515 Serine/threonine protein kinase; putative serine/threonine protein kinase 66316 17440695 AFR_00290 Actinoplanes friuliensis DSM 7358 putative serine/threonine protein kinase YP_008731400.1 64928 D 1246995 CDS YP_008731401.1 556562976 17440696 66313..68106 1 NC_022657.1 COG0515 Serine/threonine protein kinase; putative serine/threonine protein kinase 68106 17440696 AFR_00295 Actinoplanes friuliensis DSM 7358 putative serine/threonine protein kinase YP_008731401.1 66313 D 1246995 CDS YP_008731402.1 556562977 17440697 complement(68166..68816) 1 NC_022657.1 COG0512 Anthranilate/para-aminobenzoate synthases component II; para-aminobenzoate synthase component II 68816 17440697 AFR_00300 Actinoplanes friuliensis DSM 7358 para-aminobenzoate synthase component II YP_008731402.1 68166 R 1246995 CDS YP_008731403.1 556562978 17440698 complement(68825..69109) 1 NC_022657.1 hypothetical protein 69109 17440698 AFR_00305 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731403.1 68825 R 1246995 CDS YP_008731404.1 556562979 17440699 complement(69121..71154) 1 NC_022657.1 COG3764 Sortase (surface protein transpeptidase); hypothetical protein 71154 17440699 AFR_00310 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731404.1 69121 R 1246995 CDS YP_008731405.1 556562980 17440700 complement(72318..73013) 1 NC_022657.1 COG3879 Uncharacterized protein conserved in bacteria; hypothetical protein 73013 17440700 AFR_00315 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731405.1 72318 R 1246995 CDS YP_008731406.1 556562981 17440701 73297..73560 1 NC_022657.1 whiP-like uncharacterized membrane protein 73560 17440701 AFR_00320 Actinoplanes friuliensis DSM 7358 whiP-like uncharacterized membrane protein YP_008731406.1 73297 D 1246995 CDS YP_008731407.1 556562982 17440702 73757..75898 1 NC_022657.1 COG0247 Fe-S oxidoreductase; hypothetical protein 75898 17440702 AFR_00325 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731407.1 73757 D 1246995 CDS YP_008731408.1 556562983 17440703 complement(75895..76557) 1 NC_022657.1 hypothetical protein 76557 17440703 AFR_00330 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731408.1 75895 R 1246995 CDS YP_008731409.1 556562984 17440704 76659..77993 1 NC_022657.1 COG1253 Hemolysins and related proteins containing CBS domains; hypothetical protein 77993 17440704 AFR_00335 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731409.1 76659 D 1246995 CDS YP_008731410.1 556562985 17440705 77959..79011 1 NC_022657.1 COG1253 Hemolysins and related proteins containing CBS domains; hypothetical protein 79011 17440705 AFR_00340 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731410.1 77959 D 1246995 CDS YP_008731411.1 556562986 17440706 79077..79961 1 NC_022657.1 hypothetical protein 79961 17440706 AFR_00345 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731411.1 79077 D 1246995 CDS YP_008731412.1 556562987 17440707 80041..80562 1 NC_022657.1 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; ECF subfamily RNA polymerase sigma-24 subunit 80562 17440707 AFR_00350 Actinoplanes friuliensis DSM 7358 ECF subfamily RNA polymerase sigma-24 subunit YP_008731412.1 80041 D 1246995 CDS YP_008731413.1 556562988 17440708 80595..81386 1 NC_022657.1 hypothetical protein 81386 17440708 AFR_00355 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731413.1 80595 D 1246995 CDS YP_008731414.1 556562989 17440709 complement(81376..82554) 1 NC_022657.1 putative DNA-binding protein 82554 17440709 AFR_00360 Actinoplanes friuliensis DSM 7358 putative DNA-binding protein YP_008731414.1 81376 R 1246995 CDS YP_008731415.1 556562990 17440710 complement(82634..83155) 1 NC_022657.1 COG1051 ADP-ribose pyrophosphatase; MutT/nudix family protein 83155 17440710 AFR_00365 Actinoplanes friuliensis DSM 7358 MutT/nudix family protein YP_008731415.1 82634 R 1246995 CDS YP_008731416.1 556562991 17440711 83425..83709 1 NC_022657.1 hypothetical protein 83709 17440711 AFR_00370 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731416.1 83425 D 1246995 CDS YP_008731417.1 556562992 17440712 83729..84019 1 NC_022657.1 COG3620 Predicted transcriptional regulator with C-terminal CBS domains; XRE family transcriptional regulator 84019 17440712 AFR_00375 Actinoplanes friuliensis DSM 7358 XRE family transcriptional regulator YP_008731417.1 83729 D 1246995 CDS YP_008731418.1 556562993 17440714 complement(84549..85061) 1 NC_022657.1 putative pyridoxamine 5'-phosphate oxidase-related protein 85061 17440714 AFR_00380 Actinoplanes friuliensis DSM 7358 putative pyridoxamine 5'-phosphate oxidase-related protein YP_008731418.1 84549 R 1246995 CDS YP_008731419.1 556562994 17440715 85137..85715 1 NC_022657.1 COG0717 Deoxycytidine deaminase; deoxycytidine triphosphate deaminase 85715 dcd 17440715 dcd Actinoplanes friuliensis DSM 7358 deoxycytidine triphosphate deaminase YP_008731419.1 85137 D 1246995 CDS YP_008731420.1 556562995 17440716 complement(85965..86675) 1 NC_022657.1 hypothetical protein 86675 17440716 AFR_00390 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731420.1 85965 R 1246995 CDS YP_008731421.1 556562996 17440717 86819..87457 1 NC_022657.1 hypothetical protein 87457 17440717 AFR_00395 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731421.1 86819 D 1246995 CDS YP_008731422.1 556562997 17440718 87509..87790 1 NC_022657.1 COG2350 Uncharacterized protein conserved in bacteria; hypothetical protein 87790 17440718 AFR_00400 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731422.1 87509 D 1246995 CDS YP_008731423.1 556562998 17440719 complement(87787..88053) 1 NC_022657.1 aminoglycoside phosphotransferase 88053 17440719 AFR_00405 Actinoplanes friuliensis DSM 7358 aminoglycoside phosphotransferase YP_008731423.1 87787 R 1246995 CDS YP_008731424.1 556562999 17440720 complement(88110..88424) 1 NC_022657.1 hypothetical protein 88424 17440720 AFR_00410 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731424.1 88110 R 1246995 CDS YP_008731425.1 556563000 17440721 complement(88481..89029) 1 NC_022657.1 COG0503 Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins; putative phosphoribosyltransferase 89029 17440721 AFR_00415 Actinoplanes friuliensis DSM 7358 putative phosphoribosyltransferase YP_008731425.1 88481 R 1246995 CDS YP_008731426.1 556563001 17440722 89132..90259 1 NC_022657.1 COG2208 Serine phosphatase RsbU, regulator of sigma subunit; putative magnesium/manganese-dependent protein phosphatase 90259 17440722 AFR_00420 Actinoplanes friuliensis DSM 7358 putative magnesium/manganese-dependent protein phosphatase YP_008731426.1 89132 D 1246995 CDS YP_008731427.1 556563002 17440723 complement(90256..90465) 1 NC_022657.1 hypothetical protein 90465 17440723 AFR_00425 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731427.1 90256 R 1246995 CDS YP_008731428.1 556563003 17440724 90724..92580 1 NC_022657.1 COG1960 Acyl-CoA dehydrogenases; acyl-CoA dehydrogenase 92580 17440724 AFR_00430 Actinoplanes friuliensis DSM 7358 acyl-CoA dehydrogenase YP_008731428.1 90724 D 1246995 CDS YP_008731429.1 556563004 17440725 complement(92632..93147) 1 NC_022657.1 COG2062 Phosphohistidine phosphatase SixA; putative phosphohistidine phosphatase 93147 17440725 AFR_00435 Actinoplanes friuliensis DSM 7358 putative phosphohistidine phosphatase YP_008731429.1 92632 R 1246995 CDS YP_008731430.1 556563005 17440726 93252..93545 1 NC_022657.1 hypothetical protein 93545 17440726 AFR_00440 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731430.1 93252 D 1246995 CDS YP_008731431.1 556563006 17440727 complement(93599..94447) 1 NC_022657.1 COG0702 Predicted nucleoside-diphosphate-sugar epimerases; NmrA family protein 94447 17440727 AFR_00445 Actinoplanes friuliensis DSM 7358 NmrA family protein YP_008731431.1 93599 R 1246995 CDS YP_008731432.1 556563007 17440728 94592..94936 1 NC_022657.1 COG1733 Predicted transcriptional regulators; putative HxlR family transcriptional regulator 94936 17440728 AFR_00450 Actinoplanes friuliensis DSM 7358 putative HxlR family transcriptional regulator YP_008731432.1 94592 D 1246995 CDS YP_008731433.1 556563008 17440729 complement(94918..95712) 1 NC_022657.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); alpha/beta hydrolase fold protein 95712 17440729 AFR_00455 Actinoplanes friuliensis DSM 7358 alpha/beta hydrolase fold protein YP_008731433.1 94918 R 1246995 CDS YP_008731434.1 556563009 17440730 complement(95705..96382) 1 NC_022657.1 COG1272 Predicted membrane protein, hemolysin III homolog; putative channel protein 96382 17440730 AFR_00460 Actinoplanes friuliensis DSM 7358 putative channel protein YP_008731434.1 95705 R 1246995 CDS YP_008731435.1 556563010 17440731 complement(96429..98213) 1 NC_022657.1 COG0526 Thiol-disulfide isomerase and thioredoxins; alkyl hydroperoxide reductase/ thiol specific antioxidant/ mal allergen 98213 17440731 AFR_00465 Actinoplanes friuliensis DSM 7358 alkyl hydroperoxide reductase/ thiol specific antioxidant/ mal allergen YP_008731435.1 96429 R 1246995 CDS YP_008731436.1 556563011 17440732 complement(98283..102161) 1 NC_022657.1 hypothetical protein 102161 17440732 AFR_00470 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731436.1 98283 R 1246995 CDS YP_008731437.1 556563012 17440733 complement(102461..102598) 1 NC_022657.1 hypothetical protein 102598 17440733 AFR_00475 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731437.1 102461 R 1246995 CDS YP_008731438.1 556563013 17440734 complement(102763..104211) 1 NC_022657.1 COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes; putative dihydrolipoamide acyltransferase component 104211 17440734 AFR_00480 Actinoplanes friuliensis DSM 7358 putative dihydrolipoamide acyltransferase component YP_008731438.1 102763 R 1246995 CDS YP_008731439.1 556563014 17440735 complement(104217..105197) 1 NC_022657.1 COG0022 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit; putative branched-chain alpha keto acid dehydrogenase E1 beta subunit 105197 17440735 AFR_00485 Actinoplanes friuliensis DSM 7358 putative branched-chain alpha keto acid dehydrogenase E1 beta subunit YP_008731439.1 104217 R 1246995 CDS YP_008731440.1 556563015 17440736 complement(105197..106372) 1 NC_022657.1 COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit; pyruvate dehydrogenase E1 component subunit alpha 106372 17440736 AFR_00490 Actinoplanes friuliensis DSM 7358 pyruvate dehydrogenase E1 component subunit alpha YP_008731440.1 105197 R 1246995 CDS YP_008731441.1 556563016 17440737 106792..108474 1 NC_022657.1 Polycystic kidney disease protein 1-like 3 108474 17440737 AFR_00495 Actinoplanes friuliensis DSM 7358 Polycystic kidney disease protein 1-like 3 YP_008731441.1 106792 D 1246995 CDS YP_008731442.1 556563017 17440738 complement(108527..109105) 1 NC_022657.1 COG4636 Uncharacterized protein conserved in cyanobacteria; hypothetical protein 109105 17440738 AFR_00500 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731442.1 108527 R 1246995 CDS YP_008731443.1 556563018 17440739 complement(109113..110336) 1 NC_022657.1 hypothetical protein 110336 17440739 AFR_00505 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731443.1 109113 R 1246995 CDS YP_008731444.1 556563019 17440740 complement(110372..112051) 1 NC_022657.1 COG1132 ABC-type multidrug transport system, ATPase and permease components; putative GTPase 112051 17440740 AFR_00510 Actinoplanes friuliensis DSM 7358 putative GTPase YP_008731444.1 110372 R 1246995 CDS YP_008731445.1 556563020 17440741 complement(112048..114393) 1 NC_022657.1 putative GTPase 114393 17440741 AFR_00515 Actinoplanes friuliensis DSM 7358 putative GTPase YP_008731445.1 112048 R 1246995 CDS YP_008731446.1 556563021 17440742 114820..116718 1 NC_022657.1 COG0443 Molecular chaperone; molecular chaperone DnaK 116718 dnaK 17440742 dnaK Actinoplanes friuliensis DSM 7358 molecular chaperone DnaK YP_008731446.1 114820 D 1246995 CDS YP_008731447.1 556563022 17440743 116715..117338 1 NC_022657.1 COG0576 Molecular chaperone GrpE (heat shock protein); putative heat shock protein GrpE 117338 17440743 AFR_00525 Actinoplanes friuliensis DSM 7358 putative heat shock protein GrpE YP_008731447.1 116715 D 1246995 CDS YP_008731448.1 556563023 17440744 117421..118626 1 NC_022657.1 COG0484 DnaJ-class molecular chaperone with C-terminal Zn finger domain; putative chaperone protein DnaJ 118626 17440744 AFR_00530 Actinoplanes friuliensis DSM 7358 putative chaperone protein DnaJ YP_008731448.1 117421 D 1246995 CDS YP_008731449.1 556563024 17440745 118653..119093 1 NC_022657.1 COG0789 Predicted transcriptional regulators; Redox-sensitive transcriptional activator soxR 119093 17440745 AFR_00535 Actinoplanes friuliensis DSM 7358 Redox-sensitive transcriptional activator soxR YP_008731449.1 118653 D 1246995 CDS YP_008731450.1 556563025 17440746 complement(119112..119558) 1 NC_022657.1 hypothetical protein 119558 17440746 AFR_00540 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731450.1 119112 R 1246995 CDS YP_008731451.1 556563026 17440747 complement(119783..120988) 1 NC_022657.1 COG0475 Kef-type K+ transport systems, membrane components; putative sodium/proton antiporter 120988 17440747 AFR_00545 Actinoplanes friuliensis DSM 7358 putative sodium/proton antiporter YP_008731451.1 119783 R 1246995 CDS YP_008731452.1 556563027 17440748 complement(120999..121496) 1 NC_022657.1 COG0490 Putative regulatory, ligand-binding protein related to C-terminal domains of K+ channels; K(+)/H(+) antiporter subunit khtT 121496 17440748 AFR_00550 Actinoplanes friuliensis DSM 7358 K(+)/H(+) antiporter subunit khtT YP_008731452.1 120999 R 1246995 CDS YP_008731453.1 556563028 17440749 complement(121519..122733) 1 NC_022657.1 COG0477 Permeases of the major facilitator superfamily; major facilitator superfamily protein 122733 17440749 AFR_00555 Actinoplanes friuliensis DSM 7358 major facilitator superfamily protein YP_008731453.1 121519 R 1246995 CDS YP_008731454.1 556563029 17440750 122807..123712 1 NC_022657.1 hypothetical protein 123712 17440750 AFR_00560 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731454.1 122807 D 1246995 CDS YP_008731455.1 556563030 17440751 123786..126374 1 NC_022657.1 COG0542 ATPases with chaperone activity, ATP-binding subunit; putative ATP-dependent Clp protease ATP-binding subunit 126374 17440751 AFR_00565 Actinoplanes friuliensis DSM 7358 putative ATP-dependent Clp protease ATP-binding subunit YP_008731455.1 123786 D 1246995 CDS YP_008731456.1 556563031 17440752 complement(126425..126604) 1 NC_022657.1 hypothetical protein 126604 17440752 AFR_00570 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731456.1 126425 R 1246995 CDS YP_008731457.1 556563032 17440753 126977..127882 1 NC_022657.1 hypothetical protein 127882 17440753 AFR_00575 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731457.1 126977 D 1246995 CDS YP_008731458.1 556563033 17440754 127987..128793 1 NC_022657.1 Collagen alpha-6(VI) chain 128793 17440754 AFR_00580 Actinoplanes friuliensis DSM 7358 Collagen alpha-6(VI) chain YP_008731458.1 127987 D 1246995 CDS YP_008731459.1 556563034 17440755 129357..129560 1 NC_022657.1 hypothetical protein 129560 17440755 AFR_00585 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731459.1 129357 D 1246995 CDS YP_008731460.1 556563035 17440756 129618..129995 1 NC_022657.1 COG0640 Predicted transcriptional regulators; Cadmium efflux system accessory-like protein 129995 17440756 AFR_00590 Actinoplanes friuliensis DSM 7358 Cadmium efflux system accessory-like protein YP_008731460.1 129618 D 1246995 CDS YP_008731461.1 556563036 17440757 130094..130762 1 NC_022657.1 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases; putative aldolase 130762 17440757 AFR_00595 Actinoplanes friuliensis DSM 7358 putative aldolase YP_008731461.1 130094 D 1246995 CDS YP_008731462.1 556563037 17440758 complement(130924..131757) 1 NC_022657.1 COG0586 Uncharacterized membrane-associated protein; hypothetical protein 131757 17440758 AFR_00600 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731462.1 130924 R 1246995 CDS YP_008731463.1 556563038 17440759 complement(131784..134282) 1 NC_022657.1 COG4639 Predicted kinase; putative serine/threonine protein phosphatase 134282 17440759 AFR_00605 Actinoplanes friuliensis DSM 7358 putative serine/threonine protein phosphatase YP_008731463.1 131784 R 1246995 CDS YP_008731464.1 556563039 17440760 complement(134279..135694) 1 NC_022657.1 hypothetical protein 135694 17440760 AFR_00610 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731464.1 134279 R 1246995 CDS YP_008731465.1 556563040 17440761 135787..136275 1 NC_022657.1 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; ECF subfamily RNA polymerase sigma-24 subunit 136275 17440761 AFR_00615 Actinoplanes friuliensis DSM 7358 ECF subfamily RNA polymerase sigma-24 subunit YP_008731465.1 135787 D 1246995 CDS YP_008731466.1 556563041 17440762 136272..137306 1 NC_022657.1 COG1316 Transcriptional regulator; cell envelope-related transcriptional attenuator 137306 17440762 AFR_00620 Actinoplanes friuliensis DSM 7358 cell envelope-related transcriptional attenuator YP_008731466.1 136272 D 1246995 CDS YP_008731467.1 556563042 17440763 138219..138617 1 NC_022657.1 hypothetical protein 138617 17440763 AFR_00625 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731467.1 138219 D 1246995 CDS YP_008731468.1 556563043 17440764 139006..140031 1 NC_022657.1 COG0191 Fructose/tagatose bisphosphate aldolase; fructose-bisphosphate aldolase 140031 17440764 AFR_00630 Actinoplanes friuliensis DSM 7358 fructose-bisphosphate aldolase YP_008731468.1 139006 D 1246995 CDS YP_008731469.1 556563044 17440765 140101..140667 1 NC_022657.1 hypothetical protein 140667 17440765 AFR_00635 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731469.1 140101 D 1246995 CDS YP_008731470.1 556563045 17440766 complement(140675..140911) 1 NC_022657.1 hypothetical protein 140911 17440766 AFR_00640 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731470.1 140675 R 1246995 CDS YP_008731471.1 556563046 17440767 141006..141764 1 NC_022657.1 hypothetical protein 141764 17440767 AFR_00645 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731471.1 141006 D 1246995 CDS YP_008731472.1 556563047 17440768 complement(141745..142938) 1 NC_022657.1 COG1611 Predicted Rossmann fold nucleotide-binding protein; hypothetical protein 142938 17440768 AFR_00650 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731472.1 141745 R 1246995 CDS YP_008731473.1 556563048 17440769 142957..143946 1 NC_022657.1 COG1397 ADP-ribosylglycohydrolase; putative ADP-ribosylglycohydrolase 143946 17440769 AFR_00655 Actinoplanes friuliensis DSM 7358 putative ADP-ribosylglycohydrolase YP_008731473.1 142957 D 1246995 CDS YP_008731474.1 556563049 17440770 143976..144398 1 NC_022657.1 hypothetical protein 144398 17440770 AFR_00660 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731474.1 143976 D 1246995 CDS YP_008731475.1 556563050 17440771 complement(144677..145645) 1 NC_022657.1 COG0455 ATPases involved in chromosome partitioning; chromosome partitioning ATPase 145645 17440771 AFR_00665 Actinoplanes friuliensis DSM 7358 chromosome partitioning ATPase YP_008731475.1 144677 R 1246995 CDS YP_008731476.1 556563051 17440772 146637..146861 1 NC_022657.1 hypothetical protein 146861 17440772 AFR_00670 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731476.1 146637 D 1246995 CDS YP_008731477.1 556563052 17440773 complement(147293..148261) 1 NC_022657.1 hypothetical protein 148261 17440773 AFR_00675 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731477.1 147293 R 1246995 CDS YP_008731478.1 556563053 17440774 complement(148263..149555) 1 NC_022657.1 COG0104 Adenylosuccinate synthase; adenylosuccinate synthetase 149555 17440774 AFR_00680 Actinoplanes friuliensis DSM 7358 adenylosuccinate synthetase YP_008731478.1 148263 R 1246995 CDS YP_008731479.1 556563054 17440775 149785..151026 1 NC_022657.1 COG0151 Phosphoribosylamine-glycine ligase; phosphoribosylamine--glycine ligase 151026 17440775 AFR_00685 Actinoplanes friuliensis DSM 7358 phosphoribosylamine--glycine ligase YP_008731479.1 149785 D 1246995 CDS YP_008731480.1 556563055 17440776 complement(151090..151542) 1 NC_022657.1 COG3255 Putative sterol carrier protein; hypothetical protein 151542 17440776 AFR_00690 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731480.1 151090 R 1246995 CDS YP_008731481.1 556563056 17440777 151721..152218 1 NC_022657.1 COG0640 Predicted transcriptional regulators; LexA repressor 152218 17440777 AFR_00695 Actinoplanes friuliensis DSM 7358 LexA repressor YP_008731481.1 151721 D 1246995 CDS YP_008731482.1 556563057 17440778 152215..153471 1 NC_022657.1 COG0477 Permeases of the major facilitator superfamily; yfiS-like MFS-type transporter 153471 17440778 AFR_00700 Actinoplanes friuliensis DSM 7358 yfiS-like MFS-type transporter YP_008731482.1 152215 D 1246995 CDS YP_008731483.1 556563058 17440779 153468..154889 1 NC_022657.1 COG0015 Adenylosuccinate lyase; adenylosuccinate lyase 154889 17440779 AFR_00705 Actinoplanes friuliensis DSM 7358 adenylosuccinate lyase YP_008731483.1 153468 D 1246995 CDS YP_008731484.1 556563059 17440780 complement(154951..155634) 1 NC_022657.1 COG5640 Secreted trypsin-like serine protease; putative trypsin-like serine protease 155634 17440780 AFR_00710 Actinoplanes friuliensis DSM 7358 putative trypsin-like serine protease YP_008731484.1 154951 R 1246995 CDS YP_008731485.1 556563060 17440781 155959..156225 1 NC_022657.1 COG1828 Phosphoribosylformylglycinamidine (FGAM) synthase, PurS component; putative phosphoribosylformylglycinamidine synthase PurS component 156225 17440781 AFR_00715 Actinoplanes friuliensis DSM 7358 putative phosphoribosylformylglycinamidine synthase PurS component YP_008731485.1 155959 D 1246995 CDS YP_008731486.1 556563061 17440782 156222..156935 1 NC_022657.1 COG0047 Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain; phosphoribosylformylglycinamidine synthase I 156935 17440782 AFR_00720 Actinoplanes friuliensis DSM 7358 phosphoribosylformylglycinamidine synthase I YP_008731486.1 156222 D 1246995 CDS YP_008731487.1 556563062 17440783 156932..159679 1 NC_022657.1 COG0046 Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain; phosphoribosylformylglycinamidine synthase II 159679 17440783 AFR_00725 Actinoplanes friuliensis DSM 7358 phosphoribosylformylglycinamidine synthase II YP_008731487.1 156932 D 1246995 CDS YP_008731488.1 556563063 17440784 complement(159941..162001) 1 NC_022657.1 hypothetical protein 162001 17440784 AFR_00730 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731488.1 159941 R 1246995 CDS YP_008731489.1 556563064 17440785 162305..162637 1 NC_022657.1 hypothetical protein 162637 17440785 AFR_00735 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731489.1 162305 D 1246995 CDS YP_008731490.1 556563065 17440786 162716..164326 1 NC_022657.1 COG0034 Glutamine phosphoribosylpyrophosphate amidotransferase; amidophosphoribosyltransferase 164326 17440786 AFR_00740 Actinoplanes friuliensis DSM 7358 amidophosphoribosyltransferase YP_008731490.1 162716 D 1246995 CDS YP_008731491.1 556563066 17440787 164432..165574 1 NC_022657.1 COG0150 Phosphoribosylaminoimidazole (AIR) synthetase; phosphoribosylaminoimidazole synthetase 165574 17440787 AFR_00745 Actinoplanes friuliensis DSM 7358 phosphoribosylaminoimidazole synthetase YP_008731491.1 164432 D 1246995 CDS YP_008731492.1 556563067 17440788 165720..166823 1 NC_022657.1 COG0641 Arylsulfatase regulator (Fe-S oxidoreductase); hypothetical protein 166823 17440788 AFR_00750 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731492.1 165720 D 1246995 CDS YP_008731493.1 556563068 17440789 166792..167016 1 NC_022657.1 hypothetical protein 167016 17440789 AFR_00755 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731493.1 166792 D 1246995 CDS YP_008731494.1 556563069 17440790 complement(167139..167357) 1 NC_022657.1 hypothetical protein 167357 17440790 AFR_00760 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731494.1 167139 R 1246995 CDS YP_008731495.1 556563070 17440791 complement(167548..168630) 1 NC_022657.1 COG0334 Glutamate dehydrogenase/leucine dehydrogenase; leucine dehydrogenase 168630 17440791 AFR_00765 Actinoplanes friuliensis DSM 7358 leucine dehydrogenase YP_008731495.1 167548 R 1246995 CDS YP_008731496.1 556563071 17440792 168793..169632 1 NC_022657.1 hypothetical protein 169632 17440792 AFR_00770 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731496.1 168793 D 1246995 CDS YP_008731497.1 556563072 17440793 169935..170144 1 NC_022657.1 COG2452 Predicted site-specific integrase-resolvase; hypothetical protein 170144 17440793 AFR_00775 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731497.1 169935 D 1246995 CDS YP_008731498.1 556563073 17440794 complement(170223..170594) 1 NC_022657.1 hypothetical protein 170594 17440794 AFR_00780 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731498.1 170223 R 1246995 CDS YP_008731499.1 556563074 17440795 170613..171389 1 NC_022657.1 COG0500 SAM-dependent methyltransferases; putative methyltransferase 171389 17440795 AFR_00785 Actinoplanes friuliensis DSM 7358 putative methyltransferase YP_008731499.1 170613 D 1246995 CDS YP_008731500.1 556563075 17440796 171386..171946 1 NC_022657.1 COG1859 RNA:NAD 2'-phosphotransferase; putative RNA 2'-phosphotransferase 171946 17440796 AFR_00790 Actinoplanes friuliensis DSM 7358 putative RNA 2'-phosphotransferase YP_008731500.1 171386 D 1246995 CDS YP_008731501.1 556563076 17440797 172003..172572 1 NC_022657.1 hypothetical protein 172572 17440797 AFR_00795 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731501.1 172003 D 1246995 CDS YP_008731502.1 556563077 17440798 172569..173864 1 NC_022657.1 COG2339 Predicted membrane protein; hypothetical protein 173864 17440798 AFR_00800 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731502.1 172569 D 1246995 CDS YP_008731503.1 556563078 17440799 complement(173868..174116) 1 NC_022657.1 hypothetical protein 174116 17440799 AFR_00805 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731503.1 173868 R 1246995 CDS YP_008731504.1 556563079 17440800 174302..174721 1 NC_022657.1 COG2050 Uncharacterized protein, possibly involved in aromatic compounds catabolism; hypothetical protein 174721 17440800 AFR_00810 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731504.1 174302 D 1246995 CDS YP_008731505.1 556563080 17440801 174759..175148 1 NC_022657.1 hypothetical protein 175148 17440801 AFR_00815 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731505.1 174759 D 1246995 CDS YP_008731506.1 556563081 17440802 175145..175822 1 NC_022657.1 hypothetical protein 175822 17440802 AFR_00820 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731506.1 175145 D 1246995 CDS YP_008731507.1 556563082 17440803 complement(175819..176136) 1 NC_022657.1 hypothetical protein 176136 17440803 AFR_00825 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731507.1 175819 R 1246995 CDS YP_008731508.1 556563083 17440804 176299..176727 1 NC_022657.1 COG0642 Signal transduction histidine kinase; anti-sigma regulatory factor, serine/threonine protein kinase 176727 17440804 AFR_00830 Actinoplanes friuliensis DSM 7358 anti-sigma regulatory factor, serine/threonine protein kinase YP_008731508.1 176299 D 1246995 CDS YP_008731509.1 556563084 17440805 176759..177070 1 NC_022657.1 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); hypothetical protein 177070 17440805 AFR_00835 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731509.1 176759 D 1246995 CDS YP_008731510.1 556563085 17440806 complement(177067..178080) 1 NC_022657.1 COG2755 Lysophospholipase L1 and related esterases; putative GDSL-like lipase/acylhydrolase 178080 17440806 AFR_00840 Actinoplanes friuliensis DSM 7358 putative GDSL-like lipase/acylhydrolase YP_008731510.1 177067 R 1246995 CDS YP_008731511.1 556563086 17440807 complement(178221..178769) 1 NC_022657.1 hypothetical protein 178769 17440807 AFR_00845 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731511.1 178221 R 1246995 CDS YP_008731512.1 556563087 17440808 complement(178840..180048) 1 NC_022657.1 COG4941 Predicted RNA polymerase sigma factor containing a TPR repeat domain; putative RNA polymerase ECF-subfamily sigma factor 180048 17440808 AFR_00850 Actinoplanes friuliensis DSM 7358 putative RNA polymerase ECF-subfamily sigma factor YP_008731512.1 178840 R 1246995 CDS YP_008731513.1 556563088 17440809 complement(180036..180419) 1 NC_022657.1 COG3795 Uncharacterized protein conserved in bacteria; hypothetical protein 180419 17440809 AFR_00855 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731513.1 180036 R 1246995 CDS YP_008731514.1 556563089 17440810 180507..180935 1 NC_022657.1 COG4319 Ketosteroid isomerase homolog; hypothetical protein 180935 17440810 AFR_00860 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731514.1 180507 D 1246995 CDS YP_008731515.1 556563090 17440811 complement(180944..181327) 1 NC_022657.1 COG1155 Archaeal/vacuolar-type H+-ATPase subunit A; hypothetical protein 181327 17440811 AFR_00865 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731515.1 180944 R 1246995 CDS YP_008731516.1 556563091 17440812 181389..181736 1 NC_022657.1 hypothetical protein 181736 17440812 AFR_00870 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731516.1 181389 D 1246995 CDS YP_008731517.1 556563092 17440816 complement(182297..183355) 1 NC_022657.1 COG0789 Predicted transcriptional regulators; regulatory protein MerR 183355 17440816 AFR_00875 Actinoplanes friuliensis DSM 7358 regulatory protein MerR YP_008731517.1 182297 R 1246995 CDS YP_008731518.1 556563093 17440817 complement(183345..183935) 1 NC_022657.1 COG1443 Isopentenyldiphosphate isomerase; isopentenyl-diphosphate delta-isomerase 183935 17440817 AFR_00880 Actinoplanes friuliensis DSM 7358 isopentenyl-diphosphate delta-isomerase YP_008731518.1 183345 R 1246995 CDS YP_008731519.1 556563094 17440818 complement(183932..185410) 1 NC_022657.1 COG1233 Phytoene dehydrogenase and related proteins; zeta-phytoene desaturase 185410 17440818 AFR_00885 Actinoplanes friuliensis DSM 7358 zeta-phytoene desaturase YP_008731519.1 183932 R 1246995 CDS YP_008731520.1 556563095 17440819 complement(185450..186613) 1 NC_022657.1 COG0142 Geranylgeranyl pyrophosphate synthase; polyprenyl synthetase 186613 17440819 AFR_00890 Actinoplanes friuliensis DSM 7358 polyprenyl synthetase YP_008731520.1 185450 R 1246995 CDS YP_008731521.1 556563096 17440820 186674..187579 1 NC_022657.1 COG1562 Phytoene/squalene synthetase; putative phytoene synthase 187579 17440820 AFR_00895 Actinoplanes friuliensis DSM 7358 putative phytoene synthase YP_008731521.1 186674 D 1246995 CDS YP_008731522.1 556563097 17440821 187581..188915 1 NC_022657.1 COG0415 Deoxyribodipyrimidine photolyase; deoxyribodipyrimidine photo-lyase 188915 17440821 AFR_00900 Actinoplanes friuliensis DSM 7358 deoxyribodipyrimidine photo-lyase YP_008731522.1 187581 D 1246995 CDS YP_008731523.1 556563098 17440822 complement(189053..189871) 1 NC_022657.1 hypothetical protein 189871 17440822 AFR_00905 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731523.1 189053 R 1246995 CDS YP_008731524.1 556563099 17440823 complement(189980..190972) 1 NC_022657.1 COG1680 Beta-lactamase class C and other penicillin binding proteins; beta-lactamase 190972 17440823 AFR_00910 Actinoplanes friuliensis DSM 7358 beta-lactamase YP_008731524.1 189980 R 1246995 CDS YP_008731525.1 556563100 17440824 191110..192471 1 NC_022657.1 COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes; putative pyridine nucleotide-disulfide oxidoreductase 192471 17440824 AFR_00915 Actinoplanes friuliensis DSM 7358 putative pyridine nucleotide-disulfide oxidoreductase YP_008731525.1 191110 D 1246995 CDS YP_008731526.1 556563101 17440825 complement(192468..192848) 1 NC_022657.1 COG0642 Signal transduction histidine kinase; ATP-binding region ATPase domain-containing protein 192848 17440825 AFR_00920 Actinoplanes friuliensis DSM 7358 ATP-binding region ATPase domain-containing protein YP_008731526.1 192468 R 1246995 CDS YP_008731527.1 556563102 17440826 complement(192928..193785) 1 NC_022657.1 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); hypothetical protein 193785 17440826 AFR_00925 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731527.1 192928 R 1246995 CDS YP_008731528.1 556563103 17440827 193885..194739 1 NC_022657.1 COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases; hypothetical protein 194739 17440827 AFR_00930 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731528.1 193885 D 1246995 CDS YP_008731529.1 556563104 17440831 200581..201393 1 NC_022657.1 hypothetical protein 201393 17440831 AFR_00935 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731529.1 200581 D 1246995 CDS YP_008731530.1 556563105 17440832 complement(201390..202775) 1 NC_022657.1 COG0277 FAD/FMN-containing dehydrogenases; FAD linked oxidase domain-containing protein 202775 17440832 AFR_00940 Actinoplanes friuliensis DSM 7358 FAD linked oxidase domain-containing protein YP_008731530.1 201390 R 1246995 CDS YP_008731531.1 556563106 17440833 complement(202772..203581) 1 NC_022657.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); alpha/beta hydrolase fold protein 203581 17440833 AFR_00945 Actinoplanes friuliensis DSM 7358 alpha/beta hydrolase fold protein YP_008731531.1 202772 R 1246995 CDS YP_008731532.1 556563107 17440834 complement(203608..205410) 1 NC_022657.1 COG1409 Predicted phosphohydrolases; metallophosphoesterase 205410 17440834 AFR_00950 Actinoplanes friuliensis DSM 7358 metallophosphoesterase YP_008731532.1 203608 R 1246995 CDS YP_008731533.1 556563108 17440835 205506..206684 1 NC_022657.1 COG0438 Glycosyltransferase; putative glycosyltransferase 206684 17440835 AFR_00955 Actinoplanes friuliensis DSM 7358 putative glycosyltransferase YP_008731533.1 205506 D 1246995 CDS YP_008731534.1 556563109 17440836 206681..207811 1 NC_022657.1 COG0438 Glycosyltransferase; group 1 glycosyl transferase 207811 17440836 AFR_00960 Actinoplanes friuliensis DSM 7358 group 1 glycosyl transferase YP_008731534.1 206681 D 1246995 CDS YP_008731535.1 556563110 17440837 complement(207824..208576) 1 NC_022657.1 COG3861 Uncharacterized protein conserved in bacteria; hypothetical protein 208576 17440837 AFR_00965 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731535.1 207824 R 1246995 CDS YP_008731536.1 556563111 17440838 complement(208682..209455) 1 NC_022657.1 COG1309 Transcriptional regulator; Tetracycline repressor protein class H 209455 17440838 AFR_00970 Actinoplanes friuliensis DSM 7358 Tetracycline repressor protein class H YP_008731536.1 208682 R 1246995 CDS YP_008731537.1 556563112 17440839 209613..210677 1 NC_022657.1 COG1295 Predicted membrane protein; hypothetical protein 210677 17440839 AFR_00975 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731537.1 209613 D 1246995 CDS YP_008731538.1 556563113 17440840 210697..211113 1 NC_022657.1 hypothetical protein 211113 17440840 AFR_00980 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731538.1 210697 D 1246995 CDS YP_008731539.1 556563114 17440841 211110..211433 1 NC_022657.1 hypothetical protein 211433 17440841 AFR_00985 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731539.1 211110 D 1246995 CDS YP_008731540.1 556563115 17440842 211430..211702 1 NC_022657.1 hypothetical protein 211702 17440842 AFR_00990 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731540.1 211430 D 1246995 CDS YP_008731541.1 556563116 17440843 211740..212027 1 NC_022657.1 hypothetical protein 212027 17440843 AFR_00995 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731541.1 211740 D 1246995 CDS YP_008731542.1 556563117 17440844 complement(212084..212950) 1 NC_022657.1 aminoglycoside phosphotransferase 212950 17440844 AFR_01000 Actinoplanes friuliensis DSM 7358 aminoglycoside phosphotransferase YP_008731542.1 212084 R 1246995 CDS YP_008731543.1 556563118 17440845 complement(213138..213521) 1 NC_022657.1 hypothetical protein 213521 17440845 AFR_01005 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731543.1 213138 R 1246995 CDS YP_008731544.1 556563119 17440847 complement(213953..215221) 1 NC_022657.1 COG2931 RTX toxins and related Ca2+-binding proteins; hypothetical protein 215221 17440847 AFR_01010 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731544.1 213953 R 1246995 CDS YP_008731545.1 556563120 17440848 215431..215700 1 NC_022657.1 hypothetical protein 215700 17440848 AFR_01015 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731545.1 215431 D 1246995 CDS YP_008731546.1 556563121 17440849 215733..216458 1 NC_022657.1 COG1082 Sugar phosphate isomerases/epimerases; xylose isomerase 216458 17440849 AFR_01020 Actinoplanes friuliensis DSM 7358 xylose isomerase YP_008731546.1 215733 D 1246995 CDS YP_008731547.1 556563122 17440850 216455..217537 1 NC_022657.1 COG0673 Predicted dehydrogenases and related proteins; oxidoreductase domain-containing protein 217537 17440850 AFR_01025 Actinoplanes friuliensis DSM 7358 oxidoreductase domain-containing protein YP_008731547.1 216455 D 1246995 CDS YP_008731548.1 556563123 17440851 complement(217534..218124) 1 NC_022657.1 COG1309 Transcriptional regulator; TetR family transcriptional regulator 218124 17440851 AFR_01030 Actinoplanes friuliensis DSM 7358 TetR family transcriptional regulator YP_008731548.1 217534 R 1246995 CDS YP_008731549.1 556563124 17440852 complement(218132..219412) 1 NC_022657.1 COG4941 Predicted RNA polymerase sigma factor containing a TPR repeat domain; hypothetical protein 219412 17440852 AFR_01035 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731549.1 218132 R 1246995 CDS YP_008731550.1 556563125 17440853 complement(219443..219883) 1 NC_022657.1 COG3795 Uncharacterized protein conserved in bacteria; hypothetical protein 219883 17440853 AFR_01040 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731550.1 219443 R 1246995 CDS YP_008731551.1 556563126 17440854 complement(219962..220222) 1 NC_022657.1 COG3655 Predicted transcriptional regulator; XRE family transcriptional regulator 220222 17440854 AFR_01045 Actinoplanes friuliensis DSM 7358 XRE family transcriptional regulator YP_008731551.1 219962 R 1246995 CDS YP_008731552.1 556563127 17440855 complement(220222..220770) 1 NC_022657.1 hypothetical protein 220770 17440855 AFR_01050 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731552.1 220222 R 1246995 CDS YP_008731553.1 556563128 17440856 220921..221355 1 NC_022657.1 COG2207 AraC-type DNA-binding domain-containing proteins; AraC family transcriptional regulator 221355 17440856 AFR_01055 Actinoplanes friuliensis DSM 7358 AraC family transcriptional regulator YP_008731553.1 220921 D 1246995 CDS YP_008731554.1 556563129 17440857 221396..221803 1 NC_022657.1 COG0346 Lactoylglutathione lyase and related lyases; glyoxalase/bleomycin resistance protein/dioxygenase 221803 17440857 AFR_01060 Actinoplanes friuliensis DSM 7358 glyoxalase/bleomycin resistance protein/dioxygenase YP_008731554.1 221396 D 1246995 CDS YP_008731555.1 556563130 17440858 221853..222854 1 NC_022657.1 COG0653 Preprotein translocase subunit SecA (ATPase, RNA helicase); hypothetical protein 222854 17440858 AFR_01065 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731555.1 221853 D 1246995 CDS YP_008731556.1 556563131 17440859 complement(222859..223752) 1 NC_022657.1 COG0583 Transcriptional regulator; LysR family transcriptional regulator 223752 17440859 AFR_01070 Actinoplanes friuliensis DSM 7358 LysR family transcriptional regulator YP_008731556.1 222859 R 1246995 CDS YP_008731557.1 556563132 17440860 223822..224583 1 NC_022657.1 COG0317 Guanosine polyphosphate pyrophosphohydrolases/synthetases; metal dependent phosphohydrolase 224583 17440860 AFR_01075 Actinoplanes friuliensis DSM 7358 metal dependent phosphohydrolase YP_008731557.1 223822 D 1246995 CDS YP_008731558.1 556563133 17440861 complement(224534..225442) 1 NC_022657.1 COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases); aldo/keto reductase 225442 17440861 AFR_01080 Actinoplanes friuliensis DSM 7358 aldo/keto reductase YP_008731558.1 224534 R 1246995 CDS YP_008731559.1 556563134 17440862 complement(225521..225721) 1 NC_022657.1 hypothetical protein 225721 17440862 AFR_01085 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731559.1 225521 R 1246995 CDS YP_008731560.1 556563135 17440863 complement(225776..226279) 1 NC_022657.1 hypothetical protein 226279 17440863 AFR_01090 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731560.1 225776 R 1246995 CDS YP_008731561.1 556563136 17440864 complement(226276..227184) 1 NC_022657.1 COG0510 Predicted choline kinase involved in LPS biosynthesis; putative phosphotransferase 227184 17440864 AFR_01095 Actinoplanes friuliensis DSM 7358 putative phosphotransferase YP_008731561.1 226276 R 1246995 CDS YP_008731562.1 556563137 17440865 complement(227147..228556) 1 NC_022657.1 COG0642 Signal transduction histidine kinase; Osmosensitive K+ channel histidine kinase KdpD 228556 17440865 AFR_01100 Actinoplanes friuliensis DSM 7358 Osmosensitive K+ channel histidine kinase KdpD YP_008731562.1 227147 R 1246995 CDS YP_008731563.1 556563138 17440866 complement(228553..229227) 1 NC_022657.1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; winged helix family two component transcriptional regulator 229227 17440866 AFR_01105 Actinoplanes friuliensis DSM 7358 winged helix family two component transcriptional regulator YP_008731563.1 228553 R 1246995 CDS YP_008731564.1 556563139 17440867 229369..229902 1 NC_022657.1 hypothetical protein 229902 17440867 AFR_01110 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731564.1 229369 D 1246995 CDS YP_008731565.1 556563140 17440868 229902..230966 1 NC_022657.1 peptidoglycan-binding domain 1 protein 230966 17440868 AFR_01115 Actinoplanes friuliensis DSM 7358 peptidoglycan-binding domain 1 protein YP_008731565.1 229902 D 1246995 CDS YP_008731566.1 556563141 17440869 230963..231655 1 NC_022657.1 COG1136 ABC-type antimicrobial peptide transport system, ATPase component; ABC transporter 231655 17440869 AFR_01120 Actinoplanes friuliensis DSM 7358 ABC transporter YP_008731566.1 230963 D 1246995 CDS YP_008731567.1 556563142 17440870 231652..232860 1 NC_022657.1 COG0577 ABC-type antimicrobial peptide transport system, permease component; ABC transporter permease 232860 17440870 AFR_01125 Actinoplanes friuliensis DSM 7358 ABC transporter permease YP_008731567.1 231652 D 1246995 CDS YP_008731568.1 556563143 17440871 232907..233227 1 NC_022657.1 hypothetical protein 233227 17440871 AFR_01130 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731568.1 232907 D 1246995 CDS YP_008731569.1 556563144 17440872 233420..234781 1 NC_022657.1 COG0840 Methyl-accepting chemotaxis protein; methyl-accepting chemotaxis sensory transducer 234781 17440872 AFR_01135 Actinoplanes friuliensis DSM 7358 methyl-accepting chemotaxis sensory transducer YP_008731569.1 233420 D 1246995 CDS YP_008731570.1 556563145 17440873 234980..236197 1 NC_022657.1 COG1158 Transcription termination factor; transcription termination factor Rho 236197 17440873 AFR_01140 Actinoplanes friuliensis DSM 7358 transcription termination factor Rho YP_008731570.1 234980 D 1246995 CDS YP_008731571.1 556563146 17440874 complement(236199..236843) 1 NC_022657.1 COG2335 Secreted and surface protein containing fasciclin-like repeats; beta-Ig-H3/fasciclin 236843 17440874 AFR_01145 Actinoplanes friuliensis DSM 7358 beta-Ig-H3/fasciclin YP_008731571.1 236199 R 1246995 CDS YP_008731572.1 556563147 17440875 complement(236941..237702) 1 NC_022657.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); alpha/beta hydrolase fold protein 237702 17440875 AFR_01150 Actinoplanes friuliensis DSM 7358 alpha/beta hydrolase fold protein YP_008731572.1 236941 R 1246995 CDS YP_008731573.1 556563148 17440876 237948..238388 1 NC_022657.1 hypothetical protein 238388 17440876 AFR_01155 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731573.1 237948 D 1246995 CDS YP_008731574.1 556563149 17440877 238435..239838 1 NC_022657.1 COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes; soluble pyridine nucleotide transhydrogenase 239838 17440877 AFR_01160 Actinoplanes friuliensis DSM 7358 soluble pyridine nucleotide transhydrogenase YP_008731574.1 238435 D 1246995 CDS YP_008731575.1 556563150 17440878 complement(239839..240615) 1 NC_022657.1 COG3409 Putative peptidoglycan-binding domain-containing protein; Spore cortex-lytic enzyme 240615 17440878 AFR_01165 Actinoplanes friuliensis DSM 7358 Spore cortex-lytic enzyme YP_008731575.1 239839 R 1246995 CDS YP_008731576.1 556563151 17440879 240744..241193 1 NC_022657.1 COG1309 Transcriptional regulator; hypothetical protein 241193 17440879 AFR_01170 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731576.1 240744 D 1246995 CDS YP_008731577.1 556563152 17440880 241198..241551 1 NC_022657.1 hypothetical protein 241551 17440880 AFR_01175 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731577.1 241198 D 1246995 CDS YP_008731578.1 556563153 17440881 complement(241597..242862) 1 NC_022657.1 hypothetical protein 242862 17440881 AFR_01180 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731578.1 241597 R 1246995 CDS YP_008731579.1 556563154 17440882 243093..243731 1 NC_022657.1 COG5516 Conserved protein containing a Zn-ribbon-like motif, possibly RNA-binding; hypothetical protein 243731 17440882 AFR_01185 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731579.1 243093 D 1246995 CDS YP_008731580.1 556563155 17440883 243774..244541 1 NC_022657.1 COG5660 Predicted integral membrane protein; hypothetical protein 244541 17440883 AFR_01190 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731580.1 243774 D 1246995 CDS YP_008731581.1 556563156 17440884 complement(244538..244771) 1 NC_022657.1 hypothetical protein 244771 17440884 AFR_01195 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731581.1 244538 R 1246995 CDS YP_008731582.1 556563157 17440885 complement(244832..245275) 1 NC_022657.1 COG1970 Large-conductance mechanosensitive channel; large-conductance mechanosensitive channel protein 245275 17440885 AFR_01200 Actinoplanes friuliensis DSM 7358 large-conductance mechanosensitive channel protein YP_008731582.1 244832 R 1246995 CDS YP_008731583.1 556563158 17440886 complement(245399..245752) 1 NC_022657.1 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); Anti-sigma F factor antagonist 245752 17440886 AFR_01205 Actinoplanes friuliensis DSM 7358 Anti-sigma F factor antagonist YP_008731583.1 245399 R 1246995 CDS YP_008731584.1 556563159 17440887 245953..246819 1 NC_022657.1 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); RsbT co-antagonist protein rsbRD 246819 17440887 AFR_01210 Actinoplanes friuliensis DSM 7358 RsbT co-antagonist protein rsbRD YP_008731584.1 245953 D 1246995 CDS YP_008731585.1 556563160 17440888 246797..247234 1 NC_022657.1 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); putative anti-sigma factor antagonist 247234 17440888 AFR_01215 Actinoplanes friuliensis DSM 7358 putative anti-sigma factor antagonist YP_008731585.1 246797 D 1246995 CDS YP_008731586.1 556563161 17440889 247231..247650 1 NC_022657.1 COG2172 Anti-sigma regulatory factor (Ser/Thr protein kinase); anti-sigma regulatory factor, serine/threonine protein kinase 247650 17440889 AFR_01220 Actinoplanes friuliensis DSM 7358 anti-sigma regulatory factor, serine/threonine protein kinase YP_008731586.1 247231 D 1246995 CDS YP_008731587.1 556563162 17440890 247662..248678 1 NC_022657.1 COG2172 Anti-sigma regulatory factor (Ser/Thr protein kinase); putative magnesium/manganese-dependent protein phosphatase 248678 17440890 AFR_01225 Actinoplanes friuliensis DSM 7358 putative magnesium/manganese-dependent protein phosphatase YP_008731587.1 247662 D 1246995 CDS YP_008731588.1 556563163 17440891 248675..250021 1 NC_022657.1 COG0642 Signal transduction histidine kinase; putative two-component system sensor kinase 250021 17440891 AFR_01230 Actinoplanes friuliensis DSM 7358 putative two-component system sensor kinase YP_008731588.1 248675 D 1246995 CDS YP_008731589.1 556563164 17440892 250018..251568 1 NC_022657.1 COG0784 FOG: CheY-like receiver; Acetoacetate metabolism regulatory protein atoC 251568 17440892 AFR_01235 Actinoplanes friuliensis DSM 7358 Acetoacetate metabolism regulatory protein atoC YP_008731589.1 250018 D 1246995 CDS YP_008731590.1 556563165 17440893 251602..252138 1 NC_022657.1 COG1695 Predicted transcriptional regulators; Negative transcription regulator padR 252138 17440893 AFR_01240 Actinoplanes friuliensis DSM 7358 Negative transcription regulator padR YP_008731590.1 251602 D 1246995 CDS YP_008731591.1 556563166 17440894 252135..252824 1 NC_022657.1 COG1136 ABC-type antimicrobial peptide transport system, ATPase component; putative ABC transporter ATP-binding protein 252824 17440894 AFR_01245 Actinoplanes friuliensis DSM 7358 putative ABC transporter ATP-binding protein YP_008731591.1 252135 D 1246995 CDS YP_008731592.1 556563167 17440895 252821..254341 1 NC_022657.1 putative permease 254341 17440895 AFR_01250 Actinoplanes friuliensis DSM 7358 putative permease YP_008731592.1 252821 D 1246995 CDS YP_008731593.1 556563168 17440896 complement(254388..256475) 1 NC_022657.1 COG1770 Protease II; oligopeptidase B 256475 17440896 AFR_01255 Actinoplanes friuliensis DSM 7358 oligopeptidase B YP_008731593.1 254388 R 1246995 CDS YP_008731594.1 556563169 17440897 256604..257776 1 NC_022657.1 COG0277 FAD/FMN-containing dehydrogenases; hypothetical protein 257776 17440897 AFR_01260 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731594.1 256604 D 1246995 CDS YP_008731595.1 556563170 17440898 complement(257864..258487) 1 NC_022657.1 COG0262 Dihydrofolate reductase; hypothetical protein 258487 17440898 AFR_01265 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731595.1 257864 R 1246995 CDS YP_008731596.1 556563171 17440899 complement(258520..259083) 1 NC_022657.1 COG0262 Dihydrofolate reductase; hypothetical protein 259083 17440899 AFR_01270 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731596.1 258520 R 1246995 CDS YP_008731597.1 556563172 17440900 complement(259046..261553) 1 NC_022657.1 COG0438 Glycosyltransferase; phosphatidylinositol alpha-mannosyltransferase 261553 17440900 AFR_01275 Actinoplanes friuliensis DSM 7358 phosphatidylinositol alpha-mannosyltransferase YP_008731597.1 259046 R 1246995 CDS YP_008731598.1 556563173 17440901 complement(261550..264549) 1 NC_022657.1 COG0438 Glycosyltransferase; group 1 glycosyl transferase 264549 17440901 AFR_01280 Actinoplanes friuliensis DSM 7358 group 1 glycosyl transferase YP_008731598.1 261550 R 1246995 CDS YP_008731599.1 556563174 17440902 complement(264588..265358) 1 NC_022657.1 COG0463 Glycosyltransferases involved in cell wall biogenesis; family 2 glycosyl transferase 265358 17440902 AFR_01285 Actinoplanes friuliensis DSM 7358 family 2 glycosyl transferase YP_008731599.1 264588 R 1246995 CDS YP_008731600.1 556563175 17440903 complement(265703..267676) 1 NC_022657.1 COG2208 Serine phosphatase RsbU, regulator of sigma subunit; putative magnesium/manganese-dependent protein phosphatase 267676 17440903 AFR_01290 Actinoplanes friuliensis DSM 7358 putative magnesium/manganese-dependent protein phosphatase YP_008731600.1 265703 R 1246995 CDS YP_008731601.1 556563176 17440904 267825..272225 1 NC_022657.1 COG2770 FOG: HAMP domain; putative multi-sensor signal transduction histidine kinase 272225 17440904 AFR_01295 Actinoplanes friuliensis DSM 7358 putative multi-sensor signal transduction histidine kinase YP_008731601.1 267825 D 1246995 CDS YP_008731602.1 556563177 17440905 272218..272766 1 NC_022657.1 COG0784 FOG: CheY-like receiver; putative response regulator receiver domain protein 272766 17440905 AFR_01300 Actinoplanes friuliensis DSM 7358 putative response regulator receiver domain protein YP_008731602.1 272218 D 1246995 CDS YP_008731603.1 556563178 17440906 complement(272763..273563) 1 NC_022657.1 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases; hypothetical protein 273563 17440906 AFR_01305 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731603.1 272763 R 1246995 CDS YP_008731604.1 556563179 17440907 complement(273644..274018) 1 NC_022657.1 COG0346 Lactoylglutathione lyase and related lyases; hypothetical protein 274018 17440907 AFR_01310 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731604.1 273644 R 1246995 CDS YP_008731605.1 556563180 17440908 complement(274130..274456) 1 NC_022657.1 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); hypothetical protein 274456 17440908 AFR_01315 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731605.1 274130 R 1246995 CDS YP_008731606.1 556563181 17440909 274603..275940 1 NC_022657.1 COG0001 Glutamate-1-semialdehyde aminotransferase; glutamate-1-semialdehyde aminotransferase 275940 17440909 AFR_01320 Actinoplanes friuliensis DSM 7358 glutamate-1-semialdehyde aminotransferase YP_008731606.1 274603 D 1246995 CDS YP_008731607.1 556563182 17440910 275937..276593 1 NC_022657.1 COG0406 Fructose-2,6-bisphosphatase; putative phosphoglycerate mutase 276593 17440910 AFR_01325 Actinoplanes friuliensis DSM 7358 putative phosphoglycerate mutase YP_008731607.1 275937 D 1246995 CDS YP_008731608.1 556563183 17440911 276590..277153 1 NC_022657.1 COG0526 Thiol-disulfide isomerase and thioredoxins; alkyl hydroperoxide reductase/thiol specific antioxidant/Mal allergen 277153 17440911 AFR_01330 Actinoplanes friuliensis DSM 7358 alkyl hydroperoxide reductase/thiol specific antioxidant/Mal allergen YP_008731608.1 276590 D 1246995 CDS YP_008731609.1 556563184 17440912 277153..277983 1 NC_022657.1 COG0785 Cytochrome c biogenesis protein; cytochrome c-type biogenesis protein 277983 17440912 AFR_01335 Actinoplanes friuliensis DSM 7358 cytochrome c-type biogenesis protein YP_008731609.1 277153 D 1246995 CDS YP_008731610.1 556563185 17440913 277980..279599 1 NC_022657.1 COG1333 ResB protein required for cytochrome c biosynthesis; putative cytochrome c biogenesis membrane protein 279599 17440913 AFR_01340 Actinoplanes friuliensis DSM 7358 putative cytochrome c biogenesis membrane protein YP_008731610.1 277980 D 1246995 CDS YP_008731611.1 556563186 17440914 279599..280573 1 NC_022657.1 COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component; putative cytochrome C assembly protein 280573 17440914 AFR_01345 Actinoplanes friuliensis DSM 7358 putative cytochrome C assembly protein YP_008731611.1 279599 D 1246995 CDS YP_008731612.1 556563187 17440915 281040..282740 1 NC_022657.1 COG1132 ABC-type multidrug transport system, ATPase and permease components; ABC transporter permease/ATP-binding protein 282740 17440915 AFR_01350 Actinoplanes friuliensis DSM 7358 ABC transporter permease/ATP-binding protein YP_008731612.1 281040 D 1246995 CDS YP_008731613.1 556563188 17440916 282812..284524 1 NC_022657.1 COG1132 ABC-type multidrug transport system, ATPase and permease components; xenobiotic-transporting ATPase 284524 17440916 AFR_01355 Actinoplanes friuliensis DSM 7358 xenobiotic-transporting ATPase YP_008731613.1 282812 D 1246995 CDS YP_008731614.1 556563189 17440917 complement(284515..285063) 1 NC_022657.1 hypothetical protein 285063 17440917 AFR_01360 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731614.1 284515 R 1246995 CDS YP_008731615.1 556563190 17440918 286456..287430 1 NC_022657.1 COG1609 Transcriptional regulators; LacI family transcriptional regulator 287430 17440918 AFR_01365 Actinoplanes friuliensis DSM 7358 LacI family transcriptional regulator YP_008731615.1 286456 D 1246995 CDS YP_008731616.1 556563191 17440919 287618..288973 1 NC_022657.1 COG1653 ABC-type sugar transport system, periplasmic component; sugar ABC transporter periplasmic protein 288973 17440919 AFR_01370 Actinoplanes friuliensis DSM 7358 sugar ABC transporter periplasmic protein YP_008731616.1 287618 D 1246995 CDS YP_008731617.1 556563192 17440920 288970..291843 1 NC_022657.1 carbohydrate binding family 6 291843 17440920 AFR_01375 Actinoplanes friuliensis DSM 7358 carbohydrate binding family 6 YP_008731617.1 288970 D 1246995 CDS YP_008731618.1 556563193 17440921 291855..293438 1 NC_022657.1 COG0366 Glycosidases; putative alpha-glucosidase 293438 17440921 AFR_01380 Actinoplanes friuliensis DSM 7358 putative alpha-glucosidase YP_008731618.1 291855 D 1246995 CDS YP_008731619.1 556563194 17440922 293435..294460 1 NC_022657.1 COG1609 Transcriptional regulators; putative LacI-family transcriptional regulator 294460 17440922 AFR_01385 Actinoplanes friuliensis DSM 7358 putative LacI-family transcriptional regulator YP_008731619.1 293435 D 1246995 CDS YP_008731620.1 556563195 17440923 294853..295359 1 NC_022657.1 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; RNA polymerase sigma factor 295359 17440923 AFR_01390 Actinoplanes friuliensis DSM 7358 RNA polymerase sigma factor YP_008731620.1 294853 D 1246995 CDS YP_008731621.1 556563196 17440924 complement(295491..296387) 1 NC_022657.1 hypothetical protein 296387 17440924 AFR_01395 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731621.1 295491 R 1246995 CDS YP_008731622.1 556563197 17440925 296510..297973 1 NC_022657.1 COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases; 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 297973 17440925 AFR_01400 Actinoplanes friuliensis DSM 7358 3-octaprenyl-4-hydroxybenzoate carboxy-lyase YP_008731622.1 296510 D 1246995 CDS YP_008731623.1 556563198 17440926 297970..298866 1 NC_022657.1 COG0382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases; prenyltransferase 298866 ubiA 17440926 ubiA Actinoplanes friuliensis DSM 7358 prenyltransferase YP_008731623.1 297970 D 1246995 CDS YP_008731624.1 556563199 17440927 298898..299425 1 NC_022657.1 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; putative RNA polymerase ECF-subfamily sigma factor 299425 17440927 AFR_01410 Actinoplanes friuliensis DSM 7358 putative RNA polymerase ECF-subfamily sigma factor YP_008731624.1 298898 D 1246995 CDS YP_008731625.1 556563200 17440928 299427..300614 1 NC_022657.1 hypothetical protein 300614 17440928 AFR_01415 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731625.1 299427 D 1246995 CDS YP_008731626.1 556563201 17440929 300629..301255 1 NC_022657.1 COG0163 3-polyprenyl-4-hydroxybenzoate decarboxylase; putative 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 301255 17440929 AFR_01420 Actinoplanes friuliensis DSM 7358 putative 3-octaprenyl-4-hydroxybenzoate carboxy-lyase YP_008731626.1 300629 D 1246995 CDS YP_008731627.1 556563202 17440930 complement(301293..301568) 1 NC_022657.1 COG2452 Predicted site-specific integrase-resolvase; putative MerR-family transcriptional regulator 301568 17440930 AFR_01425 Actinoplanes friuliensis DSM 7358 putative MerR-family transcriptional regulator YP_008731627.1 301293 R 1246995 CDS YP_008731628.1 556563203 17440931 301789..302250 1 NC_022657.1 COG1522 Transcriptional regulators; putative HTH-type transcriptional regulator 302250 17440931 AFR_01430 Actinoplanes friuliensis DSM 7358 putative HTH-type transcriptional regulator YP_008731628.1 301789 D 1246995 CDS YP_008731629.1 556563204 17440932 302254..303378 1 NC_022657.1 COG0031 Cysteine synthase; pyridoxal-5'-phosphate-dependent protein subunit beta 303378 17440932 AFR_01435 Actinoplanes friuliensis DSM 7358 pyridoxal-5'-phosphate-dependent protein subunit beta YP_008731629.1 302254 D 1246995 CDS YP_008731630.1 556563205 17440933 303422..304894 1 NC_022657.1 COG0308 Aminopeptidase N; hypothetical protein 304894 17440933 AFR_01440 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731630.1 303422 D 1246995 CDS YP_008731631.1 556563206 17440934 complement(304891..305511) 1 NC_022657.1 COG3554 Uncharacterized protein conserved in bacteria; hypothetical protein 305511 17440934 AFR_01445 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731631.1 304891 R 1246995 CDS YP_008731632.1 556563207 17440935 complement(305613..307457) 1 NC_022657.1 COG0513 Superfamily II DNA and RNA helicases; putative DEAD/DEAH box helicase 307457 17440935 AFR_01450 Actinoplanes friuliensis DSM 7358 putative DEAD/DEAH box helicase YP_008731632.1 305613 R 1246995 CDS YP_008731633.1 556563208 17440936 complement(307697..308827) 1 NC_022657.1 Polycystic kidney disease protein 1-like 3 308827 17440936 AFR_01455 Actinoplanes friuliensis DSM 7358 Polycystic kidney disease protein 1-like 3 YP_008731633.1 307697 R 1246995 CDS YP_008731634.1 556563209 17440937 308796..309314 1 NC_022657.1 hypothetical protein 309314 17440937 AFR_01460 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731634.1 308796 D 1246995 CDS YP_008731635.1 556563210 17440938 complement(309557..311203) 1 NC_022657.1 COG0791 Cell wall-associated hydrolases (invasion-associated proteins); hypothetical protein 311203 17440938 AFR_01465 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731635.1 309557 R 1246995 CDS YP_008731636.1 556563211 17440939 311420..312589 1 NC_022657.1 COG1060 Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes; FO synthase subunit 2 1 312589 17440939 AFR_01470 Actinoplanes friuliensis DSM 7358 FO synthase subunit 2 1 YP_008731636.1 311420 D 1246995 CDS YP_008731637.1 556563212 17440940 312664..313041 1 NC_022657.1 hypothetical protein 313041 17440940 AFR_01475 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731637.1 312664 D 1246995 CDS YP_008731638.1 556563213 17440941 313055..313450 1 NC_022657.1 hypothetical protein 313450 17440941 AFR_01480 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731638.1 313055 D 1246995 CDS YP_008731639.1 556563214 17440942 313592..314890 1 NC_022657.1 COG2866 Predicted carboxypeptidase; putative carboxypeptidase 314890 17440942 AFR_01485 Actinoplanes friuliensis DSM 7358 putative carboxypeptidase YP_008731639.1 313592 D 1246995 CDS YP_008731640.1 556563215 17440943 315022..315333 1 NC_022657.1 NUDIX hydrolase 315333 17440943 AFR_01490 Actinoplanes friuliensis DSM 7358 NUDIX hydrolase YP_008731640.1 315022 D 1246995 CDS YP_008731641.1 556563216 17440944 315426..315947 1 NC_022657.1 hypothetical protein 315947 17440944 AFR_01495 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731641.1 315426 D 1246995 CDS YP_008731642.1 556563217 17440945 complement(315944..318157) 1 NC_022657.1 COG1409 Predicted phosphohydrolases; hypothetical protein 318157 17440945 AFR_01500 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731642.1 315944 R 1246995 CDS YP_008731643.1 556563218 17440946 318310..318912 1 NC_022657.1 hypothetical protein 318912 17440946 AFR_01505 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731643.1 318310 D 1246995 CDS YP_008731644.1 556563219 17440947 318983..319522 1 NC_022657.1 COG1309 Transcriptional regulator; TetR family transcriptional regulator 319522 17440947 AFR_01510 Actinoplanes friuliensis DSM 7358 TetR family transcriptional regulator YP_008731644.1 318983 D 1246995 CDS YP_008731645.1 556563220 17440948 319952..320758 1 NC_022657.1 COG0614 ABC-type Fe3+-hydroxamate transport system, periplasmic component; vitamin B12-binding protein 320758 17440948 AFR_01515 Actinoplanes friuliensis DSM 7358 vitamin B12-binding protein YP_008731645.1 319952 D 1246995 CDS YP_008731646.1 556563221 17440949 321091..322080 1 NC_022657.1 COG0609 ABC-type Fe3+-siderophore transport system, permease component; putative FecCD-family membrane transport protein 322080 17440949 AFR_01520 Actinoplanes friuliensis DSM 7358 putative FecCD-family membrane transport protein YP_008731646.1 321091 D 1246995 CDS YP_008731647.1 556563222 17440950 322077..322841 1 NC_022657.1 COG1120 ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components; putative iron ABC transporter ATP-binding protein 322841 17440950 AFR_01525 Actinoplanes friuliensis DSM 7358 putative iron ABC transporter ATP-binding protein YP_008731647.1 322077 D 1246995 CDS YP_008731648.1 556563223 17440951 complement(323136..323906) 1 NC_022657.1 COG3324 Predicted enzyme related to lactoylglutathione lyase; hypothetical protein 323906 17440951 AFR_01530 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731648.1 323136 R 1246995 CDS YP_008731649.1 556563224 17440952 complement(323989..324729) 1 NC_022657.1 COG0842 ABC-type multidrug transport system, permease component; ABC transporter 324729 17440952 AFR_01535 Actinoplanes friuliensis DSM 7358 ABC transporter YP_008731649.1 323989 R 1246995 CDS YP_008731650.1 556563225 17440953 complement(324990..325856) 1 NC_022657.1 COG1131 ABC-type multidrug transport system, ATPase component; ABC transporter-like protein 325856 17440953 AFR_01540 Actinoplanes friuliensis DSM 7358 ABC transporter-like protein YP_008731650.1 324990 R 1246995 CDS YP_008731651.1 556563226 17440954 complement(325853..326209) 1 NC_022657.1 COG1846 Transcriptional regulators; MarR family transcriptional regulator 326209 17440954 AFR_01545 Actinoplanes friuliensis DSM 7358 MarR family transcriptional regulator YP_008731651.1 325853 R 1246995 CDS YP_008731652.1 556563227 17440955 complement(326206..326841) 1 NC_022657.1 hypothetical protein 326841 17440955 AFR_01550 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731652.1 326206 R 1246995 CDS YP_008731653.1 556563228 17440956 326916..327338 1 NC_022657.1 COG0456 Acetyltransferases; Acetyltransferase 327338 17440956 AFR_01555 Actinoplanes friuliensis DSM 7358 Acetyltransferase YP_008731653.1 326916 D 1246995 CDS YP_008731654.1 556563229 17440957 complement(327325..329391) 1 NC_022657.1 COG3973 Superfamily I DNA and RNA helicases; hypothetical protein 329391 17440957 AFR_01560 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731654.1 327325 R 1246995 CDS YP_008731655.1 556563230 17440958 329616..330149 1 NC_022657.1 COG0640 Predicted transcriptional regulators; putative ArsR-family transcriptional regulator 330149 17440958 AFR_01565 Actinoplanes friuliensis DSM 7358 putative ArsR-family transcriptional regulator YP_008731655.1 329616 D 1246995 CDS YP_008731656.1 556563231 17440959 330182..331432 1 NC_022657.1 COG0477 Permeases of the major facilitator superfamily; hypothetical protein 331432 17440959 AFR_01570 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731656.1 330182 D 1246995 CDS YP_008731657.1 556563232 17440960 331429..332280 1 NC_022657.1 COG1427 Predicted periplasmic solute-binding protein; hypothetical protein 332280 17440960 AFR_01575 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731657.1 331429 D 1246995 CDS YP_008731658.1 556563233 17440961 332358..333887 1 NC_022657.1 COG1361 S-layer domain; LPXTG-motif cell wall anchor domain-containing protein 333887 17440961 AFR_01580 Actinoplanes friuliensis DSM 7358 LPXTG-motif cell wall anchor domain-containing protein YP_008731658.1 332358 D 1246995 CDS YP_008731659.1 556563234 17440962 complement(333871..335148) 1 NC_022657.1 COG0463 Glycosyltransferases involved in cell wall biogenesis; glycosyltransferase 335148 17440962 AFR_01585 Actinoplanes friuliensis DSM 7358 glycosyltransferase YP_008731659.1 333871 R 1246995 CDS YP_008731660.1 556563235 17440963 complement(335138..336595) 1 NC_022657.1 hypothetical protein 336595 17440963 AFR_01590 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731660.1 335138 R 1246995 CDS YP_008731661.1 556563236 17440964 complement(336774..337730) 1 NC_022657.1 COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases; Hydroxyacid oxidase 1 337730 17440964 AFR_01595 Actinoplanes friuliensis DSM 7358 Hydroxyacid oxidase 1 YP_008731661.1 336774 R 1246995 CDS YP_008731662.1 556563237 17440965 complement(337765..338712) 1 NC_022657.1 COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases); putative aldo/keto reductase 338712 17440965 AFR_01600 Actinoplanes friuliensis DSM 7358 putative aldo/keto reductase YP_008731662.1 337765 R 1246995 CDS YP_008731663.1 556563238 17440966 338911..340473 1 NC_022657.1 glucan endo-1,3-beta-d-glucosidase 340473 17440966 AFR_01605 Actinoplanes friuliensis DSM 7358 glucan endo-1,3-beta-d-glucosidase YP_008731663.1 338911 D 1246995 CDS YP_008731664.1 556563239 17440967 complement(340523..341356) 1 NC_022657.1 COG4279 Uncharacterized conserved protein; hypothetical protein 341356 17440967 AFR_01610 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731664.1 340523 R 1246995 CDS YP_008731665.1 556563240 17440968 complement(341358..344309) 1 NC_022657.1 COG0553 Superfamily II DNA/RNA helicases, SNF2 family; putative SNF2-family helicase 344309 17440968 AFR_01615 Actinoplanes friuliensis DSM 7358 putative SNF2-family helicase YP_008731665.1 341358 R 1246995 CDS YP_008731666.1 556563241 17440969 complement(344494..344874) 1 NC_022657.1 COG0346 Lactoylglutathione lyase and related lyases; hypothetical protein 344874 17440969 AFR_01620 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731666.1 344494 R 1246995 CDS YP_008731667.1 556563242 17440970 344937..345692 1 NC_022657.1 COG1309 Transcriptional regulator; Tetracycline repressor protein class E 345692 17440970 AFR_01625 Actinoplanes friuliensis DSM 7358 Tetracycline repressor protein class E YP_008731667.1 344937 D 1246995 CDS YP_008731668.1 556563243 17440971 345726..346967 1 NC_022657.1 COG1060 Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes; radical SAM domain-containing protein 346967 17440971 AFR_01630 Actinoplanes friuliensis DSM 7358 radical SAM domain-containing protein YP_008731668.1 345726 D 1246995 CDS YP_008731669.1 556563244 17440972 346987..347754 1 NC_022657.1 hypothetical protein 347754 17440972 AFR_01635 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731669.1 346987 D 1246995 CDS YP_008731670.1 556563245 17440973 348071..348766 1 NC_022657.1 COG2226 Methylase involved in ubiquinone/menaquinone biosynthesis; ubiquinone/menaquinone biosynthesis methyltransferase 348766 17440973 AFR_01640 Actinoplanes friuliensis DSM 7358 ubiquinone/menaquinone biosynthesis methyltransferase YP_008731670.1 348071 D 1246995 CDS YP_008731671.1 556563246 17440974 348818..349111 1 NC_022657.1 hypothetical protein 349111 17440974 AFR_01645 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731671.1 348818 D 1246995 CDS YP_008731672.1 556563247 17440975 349210..350508 1 NC_022657.1 COG0644 Dehydrogenases (flavoproteins); putative FAD-dependent oxidoreductase 350508 17440975 AFR_01650 Actinoplanes friuliensis DSM 7358 putative FAD-dependent oxidoreductase YP_008731672.1 349210 D 1246995 CDS YP_008731673.1 556563248 17440976 350588..350953 1 NC_022657.1 COG0838 NADH:ubiquinone oxidoreductase subunit 3 (chain A); NADH dehydrogenase subunit A 350953 17440976 AFR_01655 Actinoplanes friuliensis DSM 7358 NADH dehydrogenase subunit A YP_008731673.1 350588 D 1246995 CDS YP_008731674.1 556563249 17440977 350959..351630 1 NC_022657.1 COG0377 NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases; NADH dehydrogenase subunit B 351630 17440977 AFR_01660 Actinoplanes friuliensis DSM 7358 NADH dehydrogenase subunit B YP_008731674.1 350959 D 1246995 CDS YP_008731675.1 556563250 17440978 351627..352319 1 NC_022657.1 COG0852 NADH:ubiquinone oxidoreductase 27 kD subunit; NADH dehydrogenase subunit C 352319 17440978 AFR_01665 Actinoplanes friuliensis DSM 7358 NADH dehydrogenase subunit C YP_008731675.1 351627 D 1246995 CDS YP_008731676.1 556563251 17440979 352316..353641 1 NC_022657.1 COG0649 NADH:ubiquinone oxidoreductase 49 kD subunit 7; NADH dehydrogenase subunit D 353641 17440979 AFR_01670 Actinoplanes friuliensis DSM 7358 NADH dehydrogenase subunit D YP_008731676.1 352316 D 1246995 CDS YP_008731677.1 556563252 17440980 353642..354748 1 NC_022657.1 COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit; NADH dehydrogenase subunit E 354748 17440980 AFR_01675 Actinoplanes friuliensis DSM 7358 NADH dehydrogenase subunit E YP_008731677.1 353642 D 1246995 CDS YP_008731678.1 556563253 17440981 354745..356061 1 NC_022657.1 COG1894 NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit; NADH dehydrogenase I subunit F 356061 17440981 AFR_01680 Actinoplanes friuliensis DSM 7358 NADH dehydrogenase I subunit F YP_008731678.1 354745 D 1246995 CDS YP_008731679.1 556563254 17440982 356061..358535 1 NC_022657.1 COG1034 NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G); NADH dehydrogenase subunit G 358535 17440982 AFR_01685 Actinoplanes friuliensis DSM 7358 NADH dehydrogenase subunit G YP_008731679.1 356061 D 1246995 CDS YP_008731680.1 556563255 17440983 358535..359929 1 NC_022657.1 COG1005 NADH:ubiquinone oxidoreductase subunit 1 (chain H); NADH:ubiquinone oxidoreductase subunit H 359929 17440983 AFR_01690 Actinoplanes friuliensis DSM 7358 NADH:ubiquinone oxidoreductase subunit H YP_008731680.1 358535 D 1246995 CDS YP_008731681.1 556563256 17440984 359931..360587 1 NC_022657.1 COG1143 Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I); putative NADH dehydrogenase I chain I 360587 17440984 AFR_01695 Actinoplanes friuliensis DSM 7358 putative NADH dehydrogenase I chain I YP_008731681.1 359931 D 1246995 CDS YP_008731682.1 556563257 17440985 360584..361351 1 NC_022657.1 COG0839 NADH:ubiquinone oxidoreductase subunit 6 (chain J); NADH:ubiquinone oxidoreductase subunit J 361351 17440985 AFR_01700 Actinoplanes friuliensis DSM 7358 NADH:ubiquinone oxidoreductase subunit J YP_008731682.1 360584 D 1246995 CDS YP_008731683.1 556563258 17440986 361348..361647 1 NC_022657.1 COG0713 NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K); NADH:ubiquinone oxidoreductase subunit K 361647 17440986 AFR_01705 Actinoplanes friuliensis DSM 7358 NADH:ubiquinone oxidoreductase subunit K YP_008731683.1 361348 D 1246995 CDS YP_008731684.1 556563259 17440987 361660..363585 1 NC_022657.1 COG1009 NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit; NADH:ubiquinone oxidoreductase subunit L 363585 17440987 AFR_01710 Actinoplanes friuliensis DSM 7358 NADH:ubiquinone oxidoreductase subunit L YP_008731684.1 361660 D 1246995 CDS YP_008731685.1 556563260 17440988 363582..365120 1 NC_022657.1 COG1008 NADH:ubiquinone oxidoreductase subunit 4 (chain M); putative NADH dehydrogenase I chain M 365120 17440988 AFR_01715 Actinoplanes friuliensis DSM 7358 putative NADH dehydrogenase I chain M YP_008731685.1 363582 D 1246995 CDS YP_008731686.1 556563261 17440989 365123..366655 1 NC_022657.1 COG1007 NADH:ubiquinone oxidoreductase subunit 2 (chain N); NADH:ubiquinone oxidoreductase subunit N 366655 17440989 AFR_01720 Actinoplanes friuliensis DSM 7358 NADH:ubiquinone oxidoreductase subunit N YP_008731686.1 365123 D 1246995 CDS YP_008731687.1 556563262 17440990 368577..369593 1 NC_022657.1 COG0142 Geranylgeranyl pyrophosphate synthase; putative polyprenyl diphosphate synthetase 369593 17440990 AFR_01725 Actinoplanes friuliensis DSM 7358 putative polyprenyl diphosphate synthetase YP_008731687.1 368577 D 1246995 CDS YP_008731688.1 556563263 17440991 complement(369642..370775) 1 NC_022657.1 COG0477 Permeases of the major facilitator superfamily; putative MFS transporter 370775 17440991 AFR_01730 Actinoplanes friuliensis DSM 7358 putative MFS transporter YP_008731688.1 369642 R 1246995 CDS YP_008731689.1 556563264 17440992 371001..371795 1 NC_022657.1 COG1414 Transcriptional regulator; putative IclR-family transcriptional regulator 371795 17440992 AFR_01735 Actinoplanes friuliensis DSM 7358 putative IclR-family transcriptional regulator YP_008731689.1 371001 D 1246995 CDS YP_008731690.1 556563265 17440993 371878..372393 1 NC_022657.1 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; RNA polymerase, sigma-24 subunit, ecf subfamily protein 372393 17440993 AFR_01740 Actinoplanes friuliensis DSM 7358 RNA polymerase, sigma-24 subunit, ecf subfamily protein YP_008731690.1 371878 D 1246995 CDS YP_008731691.1 556563266 17440994 372390..373100 1 NC_022657.1 hypothetical protein 373100 17440994 AFR_01745 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731691.1 372390 D 1246995 CDS YP_008731692.1 556563267 17440995 complement(373113..374066) 1 NC_022657.1 COG2962 Predicted permeases; hypothetical protein 374066 17440995 AFR_01750 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731692.1 373113 R 1246995 CDS YP_008731693.1 556563268 17440996 complement(374118..374570) 1 NC_022657.1 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; GCN5-like N-acetyltransferase 374570 17440996 AFR_01755 Actinoplanes friuliensis DSM 7358 GCN5-like N-acetyltransferase YP_008731693.1 374118 R 1246995 CDS YP_008731694.1 556563269 17440997 complement(374593..374979) 1 NC_022657.1 COG1950 Predicted membrane protein; hypothetical protein 374979 17440997 AFR_01760 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731694.1 374593 R 1246995 CDS YP_008731695.1 556563270 17440998 complement(375098..376822) 1 NC_022657.1 hypothetical protein 376822 17440998 AFR_01765 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731695.1 375098 R 1246995 CDS YP_008731696.1 556563271 17440999 377262..377588 1 NC_022657.1 COG4842 Uncharacterized protein conserved in bacteria; hypothetical protein 377588 17440999 AFR_01770 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731696.1 377262 D 1246995 CDS YP_008731697.1 556563272 17441000 377607..377900 1 NC_022657.1 COG4842 Uncharacterized protein conserved in bacteria; hypothetical protein 377900 17441000 AFR_01775 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731697.1 377607 D 1246995 CDS YP_008731698.1 556563273 17441001 380671..381663 1 NC_022657.1 hypothetical protein 381663 17441001 AFR_01780 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731698.1 380671 D 1246995 CDS YP_008731699.1 556563274 17441002 381663..382025 1 NC_022657.1 hypothetical protein 382025 17441002 AFR_01785 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731699.1 381663 D 1246995 CDS YP_008731700.1 556563275 17441003 complement(382029..382937) 1 NC_022657.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); alpha/beta hydrolase fold protein 382937 17441003 AFR_01790 Actinoplanes friuliensis DSM 7358 alpha/beta hydrolase fold protein YP_008731700.1 382029 R 1246995 CDS YP_008731701.1 556563276 17441004 complement(382967..383428) 1 NC_022657.1 hypothetical protein 383428 17441004 AFR_01795 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731701.1 382967 R 1246995 CDS YP_008731702.1 556563277 17441005 complement(383544..385892) 1 NC_022657.1 COG4412 Uncharacterized protein conserved in bacteria; immune inhibitor A 385892 17441005 AFR_01800 Actinoplanes friuliensis DSM 7358 immune inhibitor A YP_008731702.1 383544 R 1246995 CDS YP_008731703.1 556563278 17441006 complement(386101..386439) 1 NC_022657.1 hypothetical protein 386439 17441006 AFR_01805 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731703.1 386101 R 1246995 CDS YP_008731704.1 556563279 17441007 complement(386537..388921) 1 NC_022657.1 COG4412 Uncharacterized protein conserved in bacteria; M6 family metalloprotease domain-containing protein 388921 17441007 AFR_01810 Actinoplanes friuliensis DSM 7358 M6 family metalloprotease domain-containing protein YP_008731704.1 386537 R 1246995 CDS YP_008731705.1 556563280 17441008 complement(389180..391165) 1 NC_022657.1 COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases; acetyl-CoA synthetase 391165 17441008 AFR_01815 Actinoplanes friuliensis DSM 7358 acetyl-CoA synthetase YP_008731705.1 389180 R 1246995 CDS YP_008731706.1 556563281 17441009 391375..392118 1 NC_022657.1 hypothetical protein 392118 17441009 AFR_01820 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731706.1 391375 D 1246995 CDS YP_008731707.1 556563282 17441010 392201..392680 1 NC_022657.1 hypothetical protein 392680 17441010 AFR_01825 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731707.1 392201 D 1246995 CDS YP_008731708.1 556563283 17441011 complement(392989..393789) 1 NC_022657.1 COG0560 Phosphoserine phosphatase; putative haloacid dehalogenase-like hydrolase 393789 17441011 AFR_01830 Actinoplanes friuliensis DSM 7358 putative haloacid dehalogenase-like hydrolase YP_008731708.1 392989 R 1246995 CDS YP_008731709.1 556563284 17441012 complement(394090..394446) 1 NC_022657.1 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); Anti-sigma F factor antagonist 394446 17441012 AFR_01835 Actinoplanes friuliensis DSM 7358 Anti-sigma F factor antagonist YP_008731709.1 394090 R 1246995 CDS YP_008731710.1 556563285 17441013 394712..395761 1 NC_022657.1 hypothetical protein 395761 17441013 AFR_01840 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731710.1 394712 D 1246995 CDS YP_008731711.1 556563286 17441014 395758..396990 1 NC_022657.1 COG4962 Flp pilus assembly protein, ATPase CpaF; type ii secretion system protein e 396990 17441014 AFR_01845 Actinoplanes friuliensis DSM 7358 type ii secretion system protein e YP_008731711.1 395758 D 1246995 CDS YP_008731712.1 556563287 17441015 396987..397802 1 NC_022657.1 hypothetical protein 397802 17441015 AFR_01850 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731712.1 396987 D 1246995 CDS YP_008731713.1 556563288 17441016 398127..398774 1 NC_022657.1 type II secretion system protein 398774 17441016 AFR_01855 Actinoplanes friuliensis DSM 7358 type II secretion system protein YP_008731713.1 398127 D 1246995 CDS YP_008731714.1 556563289 17441017 398801..398992 1 NC_022657.1 hypothetical protein 398992 17441017 AFR_01860 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731714.1 398801 D 1246995 CDS YP_008731715.1 556563290 17441018 398989..399372 1 NC_022657.1 hypothetical protein 399372 17441018 AFR_01865 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731715.1 398989 D 1246995 CDS YP_008731716.1 556563291 17441019 399507..399815 1 NC_022657.1 helicase/secretion neighbourhood TadE-like protein 399815 17441019 AFR_01870 Actinoplanes friuliensis DSM 7358 helicase/secretion neighbourhood TadE-like protein YP_008731716.1 399507 D 1246995 CDS YP_008731717.1 556563292 17441020 complement(399789..402164) 1 NC_022657.1 COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster; putative DEAD/DEAH box helicase 402164 17441020 AFR_01875 Actinoplanes friuliensis DSM 7358 putative DEAD/DEAH box helicase YP_008731717.1 399789 R 1246995 CDS YP_008731718.1 556563293 17441021 402298..402669 1 NC_022657.1 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); anti-sigma-factor antagonist 402669 17441021 AFR_01880 Actinoplanes friuliensis DSM 7358 anti-sigma-factor antagonist YP_008731718.1 402298 D 1246995 CDS YP_008731719.1 556563294 17441022 402669..403106 1 NC_022657.1 COG2172 Anti-sigma regulatory factor (Ser/Thr protein kinase); putative anti-sigma factor 403106 17441022 AFR_01885 Actinoplanes friuliensis DSM 7358 putative anti-sigma factor YP_008731719.1 402669 D 1246995 CDS YP_008731720.1 556563295 17441023 403475..405799 1 NC_022657.1 COG3808 Inorganic pyrophosphatase; membrane-bound proton-translocating pyrophosphatase 405799 hppA 17441023 hppA Actinoplanes friuliensis DSM 7358 membrane-bound proton-translocating pyrophosphatase YP_008731720.1 403475 D 1246995 CDS YP_008731721.1 556563296 17441024 405875..406405 1 NC_022657.1 hypothetical protein 406405 17441024 AFR_01895 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731721.1 405875 D 1246995 CDS YP_008731722.1 556563297 17441025 406450..407238 1 NC_022657.1 hypothetical protein 407238 17441025 AFR_01900 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731722.1 406450 D 1246995 CDS YP_008731723.1 556563298 17441026 407431..410253 1 NC_022657.1 COG0550 Topoisomerase IA; putative DNA topoisomerase I 410253 17441026 AFR_01905 Actinoplanes friuliensis DSM 7358 putative DNA topoisomerase I YP_008731723.1 407431 D 1246995 CDS YP_008731724.1 556563299 17441027 complement(410287..411600) 1 NC_022657.1 COG0277 FAD/FMN-containing dehydrogenases; putative FAD-dependent oxidoreductase 411600 17441027 AFR_01910 Actinoplanes friuliensis DSM 7358 putative FAD-dependent oxidoreductase YP_008731724.1 410287 R 1246995 CDS YP_008731725.1 556563300 17441028 411816..412367 1 NC_022657.1 COG1309 Transcriptional regulator; TetR family transcriptional regulator 412367 17441028 AFR_01915 Actinoplanes friuliensis DSM 7358 TetR family transcriptional regulator YP_008731725.1 411816 D 1246995 CDS YP_008731726.1 556563301 17441029 complement(412372..413577) 1 NC_022657.1 COG3616 Predicted amino acid aldolase or racemase; hypothetical protein 413577 17441029 AFR_01920 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731726.1 412372 R 1246995 CDS YP_008731727.1 556563302 17441030 413821..416925 1 NC_022657.1 COG0477 Permeases of the major facilitator superfamily; thymidylate kinase 416925 17441030 AFR_01925 Actinoplanes friuliensis DSM 7358 thymidylate kinase YP_008731727.1 413821 D 1246995 CDS YP_008731728.1 556563303 17441031 416945..418138 1 NC_022657.1 COG0470 ATPase involved in DNA replication; DNA polymerase III subunit delta' 418138 17441031 AFR_01930 Actinoplanes friuliensis DSM 7358 DNA polymerase III subunit delta' YP_008731728.1 416945 D 1246995 CDS YP_008731729.1 556563304 17441032 418238..418564 1 NC_022657.1 hypothetical protein 418564 17441032 AFR_01935 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731729.1 418238 D 1246995 CDS YP_008731730.1 556563305 17441033 418564..418860 1 NC_022657.1 hypothetical protein 418860 17441033 AFR_01940 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731730.1 418564 D 1246995 CDS YP_008731731.1 556563306 17441034 418860..419465 1 NC_022657.1 hypothetical protein 419465 17441034 AFR_01945 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731731.1 418860 D 1246995 CDS YP_008731732.1 556563307 17441035 complement(419711..421099) 1 NC_022657.1 hypothetical protein 421099 17441035 AFR_01950 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731732.1 419711 R 1246995 CDS YP_008731733.1 556563308 17441036 421368..422207 1 NC_022657.1 COG1774 Uncharacterized homolog of PSP1; PSP1 domain-containing protein 422207 17441036 AFR_01955 Actinoplanes friuliensis DSM 7358 PSP1 domain-containing protein YP_008731733.1 421368 D 1246995 CDS YP_008731734.1 556563309 17441037 complement(422204..423670) 1 NC_022657.1 COG1961 Site-specific recombinases, DNA invertase Pin homologs; recombinase 423670 17441037 AFR_01960 Actinoplanes friuliensis DSM 7358 recombinase YP_008731734.1 422204 R 1246995 CDS YP_008731735.1 556563310 17441038 complement(423782..425473) 1 NC_022657.1 hypothetical protein 425473 17441038 AFR_01965 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731735.1 423782 R 1246995 CDS YP_008731736.1 556563311 17441040 complement(425766..426362) 1 NC_022657.1 hypothetical protein 426362 17441040 AFR_01970 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731736.1 425766 R 1246995 CDS YP_008731737.1 556563312 17441041 complement(426400..426903) 1 NC_022657.1 hypothetical protein 426903 17441041 AFR_01975 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731737.1 426400 R 1246995 CDS YP_008731738.1 556563313 17441042 complement(426921..428510) 1 NC_022657.1 COG0840 Methyl-accepting chemotaxis protein; putative methyl-accepting chemotaxis protein 428510 17441042 AFR_01980 Actinoplanes friuliensis DSM 7358 putative methyl-accepting chemotaxis protein YP_008731738.1 426921 R 1246995 CDS YP_008731739.1 556563314 17441043 complement(428538..429755) 1 NC_022657.1 COG0477 Permeases of the major facilitator superfamily; putative MFS transporter 429755 17441043 AFR_01985 Actinoplanes friuliensis DSM 7358 putative MFS transporter YP_008731739.1 428538 R 1246995 CDS YP_008731740.1 556563315 17441044 complement(429752..430318) 1 NC_022657.1 COG3226 Uncharacterized protein conserved in bacteria; putative TetR-family transcriptional regulator 430318 17441044 AFR_01990 Actinoplanes friuliensis DSM 7358 putative TetR-family transcriptional regulator YP_008731740.1 429752 R 1246995 CDS YP_008731741.1 556563316 17441045 complement(430315..430866) 1 NC_022657.1 COG0110 Acetyltransferase (isoleucine patch superfamily); putative sugar acetyltransferase 430866 17441045 AFR_01995 Actinoplanes friuliensis DSM 7358 putative sugar acetyltransferase YP_008731741.1 430315 R 1246995 CDS YP_008731742.1 556563317 17441046 430942..432078 1 NC_022657.1 COG0644 Dehydrogenases (flavoproteins); putative FAD-dependent oxidoreductase 432078 17441046 AFR_02000 Actinoplanes friuliensis DSM 7358 putative FAD-dependent oxidoreductase YP_008731742.1 430942 D 1246995 CDS YP_008731743.1 556563318 17441047 complement(432085..432570) 1 NC_022657.1 hypothetical protein 432570 17441047 AFR_02005 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731743.1 432085 R 1246995 CDS YP_008731744.1 556563319 17441048 complement(432707..432907) 1 NC_022657.1 hypothetical protein 432907 17441048 AFR_02010 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731744.1 432707 R 1246995 CDS YP_008731745.1 556563320 17441049 complement(433151..433354) 1 NC_022657.1 hypothetical protein 433354 17441049 AFR_02015 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731745.1 433151 R 1246995 CDS YP_008731746.1 556563321 17441050 complement(433433..434326) 1 NC_022657.1 helix-turn-helix domain-containing protein 434326 17441050 AFR_02020 Actinoplanes friuliensis DSM 7358 helix-turn-helix domain-containing protein YP_008731746.1 433433 R 1246995 CDS YP_008731747.1 556563322 17441051 complement(434519..434959) 1 NC_022657.1 hypothetical protein 434959 17441051 AFR_02025 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731747.1 434519 R 1246995 CDS YP_008731748.1 556563323 17441052 complement(435216..435659) 1 NC_022657.1 hypothetical protein 435659 17441052 AFR_02030 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731748.1 435216 R 1246995 CDS YP_008731749.1 556563324 17441053 complement(435934..436287) 1 NC_022657.1 COG3759 Predicted membrane protein; integral membrane protein 436287 17441053 AFR_02035 Actinoplanes friuliensis DSM 7358 integral membrane protein YP_008731749.1 435934 R 1246995 CDS YP_008731750.1 556563325 17441054 436464..436925 1 NC_022657.1 hypothetical protein 436925 17441054 AFR_02040 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731750.1 436464 D 1246995 CDS YP_008731751.1 556563326 17441055 436951..437490 1 NC_022657.1 COG0693 Putative intracellular protease/amidase; hypothetical protein 437490 17441055 AFR_02045 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731751.1 436951 D 1246995 CDS YP_008731752.1 556563327 17441056 complement(437494..437907) 1 NC_022657.1 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; putative NUDIX hydrolase 437907 17441056 AFR_02050 Actinoplanes friuliensis DSM 7358 putative NUDIX hydrolase YP_008731752.1 437494 R 1246995 CDS YP_008731753.1 556563328 17441057 complement(437996..438967) 1 NC_022657.1 COG1273 Uncharacterized conserved protein; putative Ku70/Ku80 protein 438967 17441057 AFR_02055 Actinoplanes friuliensis DSM 7358 putative Ku70/Ku80 protein YP_008731753.1 437996 R 1246995 CDS YP_008731754.1 556563329 17441058 439051..440004 1 NC_022657.1 COG1793 ATP-dependent DNA ligase; putative ATP-dependent DNA ligase 440004 17441058 AFR_02060 Actinoplanes friuliensis DSM 7358 putative ATP-dependent DNA ligase YP_008731754.1 439051 D 1246995 CDS YP_008731755.1 556563330 17441059 439994..440899 1 NC_022657.1 COG3285 Predicted eukaryotic-type DNA primase; hypothetical protein 440899 17441059 AFR_02065 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731755.1 439994 D 1246995 CDS YP_008731756.1 556563331 17441060 440948..441289 1 NC_022657.1 COG1695 Predicted transcriptional regulators; PadR-like family transcriptional regulator 441289 17441060 AFR_02070 Actinoplanes friuliensis DSM 7358 PadR-like family transcriptional regulator YP_008731756.1 440948 D 1246995 CDS YP_008731757.1 556563332 17441061 441286..441936 1 NC_022657.1 hypothetical protein 441936 17441061 AFR_02075 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731757.1 441286 D 1246995 CDS YP_008731758.1 556563333 17441062 complement(441991..443652) 1 NC_022657.1 COG1061 DNA or RNA helicases of superfamily II; putative ATP-dependent DNA helicase 443652 17441062 AFR_02080 Actinoplanes friuliensis DSM 7358 putative ATP-dependent DNA helicase YP_008731758.1 441991 R 1246995 CDS YP_008731759.1 556563334 17441063 complement(443839..446274) 1 NC_022657.1 hypothetical protein 446274 17441063 AFR_02085 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731759.1 443839 R 1246995 CDS YP_008731760.1 556563335 17441064 446359..446571 1 NC_022657.1 hypothetical protein 446571 17441064 AFR_02090 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731760.1 446359 D 1246995 CDS YP_008731761.1 556563336 17441065 446568..447194 1 NC_022657.1 COG0546 Predicted phosphatases; putative haloacid dehalogenase-like hydrolase 447194 17441065 AFR_02095 Actinoplanes friuliensis DSM 7358 putative haloacid dehalogenase-like hydrolase YP_008731761.1 446568 D 1246995 CDS YP_008731762.1 556563337 17441066 447241..447627 1 NC_022657.1 COG1278 Cold shock proteins; putative cold-shock DNA-binding domain protein 447627 17441066 AFR_02100 Actinoplanes friuliensis DSM 7358 putative cold-shock DNA-binding domain protein YP_008731762.1 447241 D 1246995 CDS YP_008731763.1 556563338 17441067 complement(447624..448439) 1 NC_022657.1 COG2107 Predicted periplasmic solute-binding protein; hypothetical protein 448439 17441067 AFR_02105 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731763.1 447624 R 1246995 CDS YP_008731764.1 556563339 17441068 complement(448535..449200) 1 NC_022657.1 COG0775 Nucleoside phosphorylase; hypothetical protein 449200 17441068 AFR_02110 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731764.1 448535 R 1246995 CDS YP_008731765.1 556563340 17441069 complement(449197..451074) 1 NC_022657.1 COG0477 Permeases of the major facilitator superfamily; major facilitator transporter 451074 17441069 AFR_02115 Actinoplanes friuliensis DSM 7358 major facilitator transporter YP_008731765.1 449197 R 1246995 CDS YP_008731766.1 556563341 17441070 451194..451997 1 NC_022657.1 hypothetical protein 451997 17441070 AFR_02120 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731766.1 451194 D 1246995 CDS YP_008731767.1 556563342 17441071 complement(451994..452329) 1 NC_022657.1 hypothetical protein 452329 17441071 AFR_02125 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731767.1 451994 R 1246995 CDS YP_008731768.1 556563343 17441072 452592..453929 1 NC_022657.1 COG2252 Permeases; putative permease 453929 17441072 AFR_02130 Actinoplanes friuliensis DSM 7358 putative permease YP_008731768.1 452592 D 1246995 CDS YP_008731769.1 556563344 17441073 454032..454475 1 NC_022657.1 COG1846 Transcriptional regulators; Multiple antibiotic resistance protein marR 454475 17441073 AFR_02135 Actinoplanes friuliensis DSM 7358 Multiple antibiotic resistance protein marR YP_008731769.1 454032 D 1246995 CDS YP_008731770.1 556563345 17441074 454577..455887 1 NC_022657.1 COG0477 Permeases of the major facilitator superfamily; putative MFS transporter 455887 17441074 AFR_02140 Actinoplanes friuliensis DSM 7358 putative MFS transporter YP_008731770.1 454577 D 1246995 CDS YP_008731771.1 556563346 17441075 complement(455889..456731) 1 NC_022657.1 COG1171 Threonine dehydratase; dehydratase 456731 17441075 AFR_02145 Actinoplanes friuliensis DSM 7358 dehydratase YP_008731771.1 455889 R 1246995 CDS YP_008731772.1 556563347 17441076 complement(457273..457902) 1 NC_022657.1 COG2186 Transcriptional regulators; GntR family transcriptional regulator 457902 17441076 AFR_02150 Actinoplanes friuliensis DSM 7358 GntR family transcriptional regulator YP_008731772.1 457273 R 1246995 CDS YP_008731773.1 556563348 17441077 458028..459173 1 NC_022657.1 COG2807 Cyanate permease; integral membrane transporter 459173 17441077 AFR_02155 Actinoplanes friuliensis DSM 7358 integral membrane transporter YP_008731773.1 458028 D 1246995 CDS YP_008731774.1 556563349 17441078 459279..459713 1 NC_022657.1 hypothetical protein 459713 17441078 AFR_02160 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731774.1 459279 D 1246995 CDS YP_008731775.1 556563350 17441079 460034..460696 1 NC_022657.1 COG1514 2'-5' RNA ligase; 2'-5' RNA ligase 460696 17441079 AFR_02165 Actinoplanes friuliensis DSM 7358 2'-5' RNA ligase YP_008731775.1 460034 D 1246995 CDS YP_008731776.1 556563351 17441080 complement(460697..461773) 1 NC_022657.1 hypothetical protein 461773 17441080 AFR_02170 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731776.1 460697 R 1246995 CDS YP_008731777.1 556563352 17441081 complement(461916..463013) 1 NC_022657.1 COG0823 Periplasmic component of the Tol biopolymer transport system; hypothetical protein 463013 17441081 AFR_02175 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731777.1 461916 R 1246995 CDS YP_008731778.1 556563353 17441082 complement(463010..463522) 1 NC_022657.1 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; ECF subfamily RNA polymerase sigma-24 subunit 463522 17441082 AFR_02180 Actinoplanes friuliensis DSM 7358 ECF subfamily RNA polymerase sigma-24 subunit YP_008731778.1 463010 R 1246995 CDS YP_008731779.1 556563354 17441083 463588..464028 1 NC_022657.1 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; putative GCN5-related N-acetyltransferase 464028 17441083 AFR_02185 Actinoplanes friuliensis DSM 7358 putative GCN5-related N-acetyltransferase YP_008731779.1 463588 D 1246995 CDS YP_008731780.1 556563355 17441084 complement(464025..465206) 1 NC_022657.1 COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; putative aminotransferase 465206 17441084 AFR_02190 Actinoplanes friuliensis DSM 7358 putative aminotransferase YP_008731780.1 464025 R 1246995 CDS YP_008731781.1 556563356 17441085 complement(465345..466466) 1 NC_022657.1 COG1932 Phosphoserine aminotransferase; phosphoserine aminotransferase 466466 17441085 AFR_02195 Actinoplanes friuliensis DSM 7358 phosphoserine aminotransferase YP_008731781.1 465345 R 1246995 CDS YP_008731782.1 556563357 17441086 complement(466497..467603) 1 NC_022657.1 COG0372 Citrate synthase; citrate synthase 2 467603 17441086 AFR_02200 Actinoplanes friuliensis DSM 7358 citrate synthase 2 YP_008731782.1 466497 R 1246995 CDS YP_008731783.1 556563358 17441087 467779..468435 1 NC_022657.1 COG0259 Pyridoxamine-phosphate oxidase; putative pyridoxamine 5'-phosphate oxidase-related protein 468435 17441087 AFR_02205 Actinoplanes friuliensis DSM 7358 putative pyridoxamine 5'-phosphate oxidase-related protein YP_008731783.1 467779 D 1246995 CDS YP_008731784.1 556563359 17441088 468447..469742 1 NC_022657.1 COG0477 Permeases of the major facilitator superfamily; putative MFS transporter 469742 17441088 AFR_02210 Actinoplanes friuliensis DSM 7358 putative MFS transporter YP_008731784.1 468447 D 1246995 CDS YP_008731785.1 556563360 17441089 469783..470682 1 NC_022657.1 COG2017 Galactose mutarotase and related enzymes; putative aldose-1-epimerase 470682 17441089 AFR_02215 Actinoplanes friuliensis DSM 7358 putative aldose-1-epimerase YP_008731785.1 469783 D 1246995 CDS YP_008731786.1 556563361 17441090 470684..471301 1 NC_022657.1 COG0778 Nitroreductase; NADPH-dependent oxidoreductase 471301 17441090 AFR_02220 Actinoplanes friuliensis DSM 7358 NADPH-dependent oxidoreductase YP_008731786.1 470684 D 1246995 CDS YP_008731787.1 556563362 17441091 471363..471659 1 NC_022657.1 hypothetical protein 471659 17441091 AFR_02225 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731787.1 471363 D 1246995 CDS YP_008731788.1 556563363 17441092 471679..472848 1 NC_022657.1 COG1960 Acyl-CoA dehydrogenases; acyl-CoA dehydrogenase domain-containing protein 472848 17441092 AFR_02230 Actinoplanes friuliensis DSM 7358 acyl-CoA dehydrogenase domain-containing protein YP_008731788.1 471679 D 1246995 CDS YP_008731789.1 556563364 17441093 472909..473646 1 NC_022657.1 hypothetical protein 473646 17441093 AFR_02235 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731789.1 472909 D 1246995 CDS YP_008731790.1 556563365 17441094 complement(473745..473936) 1 NC_022657.1 COG1983 Putative stress-responsive transcriptional regulator; phage shock protein C, PspC 473936 17441094 AFR_02240 Actinoplanes friuliensis DSM 7358 phage shock protein C, PspC YP_008731790.1 473745 R 1246995 CDS YP_008731791.1 556563366 17441095 474149..476209 1 NC_022657.1 COG0558 Phosphatidylglycerophosphate synthase; hypothetical protein 476209 17441095 AFR_02245 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731791.1 474149 D 1246995 CDS YP_008731792.1 556563367 17441096 476209..478383 1 NC_022657.1 COG0463 Glycosyltransferases involved in cell wall biogenesis; CDP-glycerol:poly(glycerophosphate) glycerophosphotransferase 478383 17441096 AFR_02250 Actinoplanes friuliensis DSM 7358 CDP-glycerol:poly(glycerophosphate) glycerophosphotransferase YP_008731792.1 476209 D 1246995 CDS YP_008731793.1 556563368 17441097 478598..479896 1 NC_022657.1 COG3839 ABC-type sugar transport systems, ATPase components; ABC transporter-like protein 479896 17441097 AFR_02255 Actinoplanes friuliensis DSM 7358 ABC transporter-like protein YP_008731793.1 478598 D 1246995 CDS YP_008731794.1 556563369 17441098 479986..480483 1 NC_022657.1 COG0642 Signal transduction histidine kinase; hypothetical protein 480483 17441098 AFR_02260 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731794.1 479986 D 1246995 CDS YP_008731795.1 556563370 17441099 480583..481299 1 NC_022657.1 COG0637 Predicted phosphatase/phosphohexomutase; hypothetical protein 481299 17441099 AFR_02265 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731795.1 480583 D 1246995 CDS YP_008731796.1 556563371 17441100 481339..483705 1 NC_022657.1 COG1554 Trehalose and maltose hydrolases (possible phosphorylases); putative glycosyl hydrolase 483705 17441100 AFR_02270 Actinoplanes friuliensis DSM 7358 putative glycosyl hydrolase YP_008731796.1 481339 D 1246995 CDS YP_008731797.1 556563372 17441101 complement(483772..484794) 1 NC_022657.1 hypothetical protein 484794 17441101 AFR_02275 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731797.1 483772 R 1246995 CDS YP_008731798.1 556563373 17441102 485356..486435 1 NC_022657.1 hypothetical protein 486435 17441102 AFR_02280 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731798.1 485356 D 1246995 CDS YP_008731799.1 556563374 17441103 complement(486457..487242) 1 NC_022657.1 COG1134 ABC-type polysaccharide/polyol phosphate transport system, ATPase component; putative ABC transporter ATP-binding protein 487242 17441103 AFR_02285 Actinoplanes friuliensis DSM 7358 putative ABC transporter ATP-binding protein YP_008731799.1 486457 R 1246995 CDS YP_008731800.1 556563375 17441104 complement(487235..488131) 1 NC_022657.1 COG1682 ABC-type polysaccharide/polyol phosphate export systems, permease component; ABC transporter permease 488131 17441104 AFR_02290 Actinoplanes friuliensis DSM 7358 ABC transporter permease YP_008731800.1 487235 R 1246995 CDS YP_008731801.1 556563376 17441105 488340..488912 1 NC_022657.1 COG1309 Transcriptional regulator; putative TetR-family transcriptional regulator 488912 17441105 AFR_02295 Actinoplanes friuliensis DSM 7358 putative TetR-family transcriptional regulator YP_008731801.1 488340 D 1246995 CDS YP_008731802.1 556563377 17441106 complement(488875..491553) 1 NC_022657.1 COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain; putative diguanylate cyclase/phosphodiesterase with PAS sensor 491553 17441106 AFR_02300 Actinoplanes friuliensis DSM 7358 putative diguanylate cyclase/phosphodiesterase with PAS sensor YP_008731802.1 488875 R 1246995 CDS YP_008731803.1 556563378 17441107 complement(491625..493058) 1 NC_022657.1 COG4833 Predicted glycosyl hydrolase; glycosyl hydrolase, family 76 493058 17441107 AFR_02305 Actinoplanes friuliensis DSM 7358 glycosyl hydrolase, family 76 YP_008731803.1 491625 R 1246995 CDS YP_008731804.1 556563379 17441108 493214..493567 1 NC_022657.1 COG3321 Polyketide synthase modules and related proteins; hypothetical protein 493567 17441108 AFR_02310 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731804.1 493214 D 1246995 CDS YP_008731805.1 556563380 17441109 493600..494205 1 NC_022657.1 COG3201 Nicotinamide mononucleotide transporter; Nicotinamide riboside transporter pnuC 494205 17441109 AFR_02315 Actinoplanes friuliensis DSM 7358 Nicotinamide riboside transporter pnuC YP_008731805.1 493600 D 1246995 CDS YP_008731806.1 556563381 17441110 494202..495275 1 NC_022657.1 COG1056 Nicotinamide mononucleotide adenylyltransferase; transcriptional regulator nadR 495275 17441110 AFR_02320 Actinoplanes friuliensis DSM 7358 transcriptional regulator nadR YP_008731806.1 494202 D 1246995 CDS YP_008731807.1 556563382 17441111 495296..495865 1 NC_022657.1 hypothetical protein 495865 17441111 AFR_02325 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731807.1 495296 D 1246995 CDS YP_008731808.1 556563383 17441112 495883..496734 1 NC_022657.1 COG3384 Uncharacterized conserved protein; extradiol ring-cleavage dioxygenase class III protein subunit B 496734 17441112 AFR_02330 Actinoplanes friuliensis DSM 7358 extradiol ring-cleavage dioxygenase class III protein subunit B YP_008731808.1 495883 D 1246995 CDS YP_008731809.1 556563384 17441113 complement(496731..497147) 1 NC_022657.1 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins; N-acetyltransferase GCN5 497147 17441113 AFR_02335 Actinoplanes friuliensis DSM 7358 N-acetyltransferase GCN5 YP_008731809.1 496731 R 1246995 CDS YP_008731810.1 556563385 17441114 complement(497255..498814) 1 NC_022657.1 COG2199 FOG: GGDEF domain; Cellulose synthesis regulatory protein 498814 17441114 AFR_02340 Actinoplanes friuliensis DSM 7358 Cellulose synthesis regulatory protein YP_008731810.1 497255 R 1246995 CDS YP_008731811.1 556563386 17441115 499062..499484 1 NC_022657.1 hypothetical protein 499484 17441115 AFR_02345 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731811.1 499062 D 1246995 CDS YP_008731812.1 556563387 17441116 499559..501259 1 NC_022657.1 laminin G sub domain 2 501259 17441116 AFR_02350 Actinoplanes friuliensis DSM 7358 laminin G sub domain 2 YP_008731812.1 499559 D 1246995 CDS YP_008731813.1 556563388 17441117 501320..502225 1 NC_022657.1 hypothetical protein 502225 17441117 AFR_02355 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731813.1 501320 D 1246995 CDS YP_008731814.1 556563389 17441118 complement(502219..502998) 1 NC_022657.1 COG4315 Uncharacterized protein conserved in bacteria; lipoprotein 502998 17441118 AFR_02360 Actinoplanes friuliensis DSM 7358 lipoprotein YP_008731814.1 502219 R 1246995 CDS YP_008731815.1 556563390 17441119 503283..503750 1 NC_022657.1 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; ECF subfamily RNA polymerase sigma-24 subunit 503750 17441119 AFR_02365 Actinoplanes friuliensis DSM 7358 ECF subfamily RNA polymerase sigma-24 subunit YP_008731815.1 503283 D 1246995 CDS YP_008731816.1 556563391 17441120 503747..504451 1 NC_022657.1 putative transmembrane anti-sigma factor 504451 17441120 AFR_02370 Actinoplanes friuliensis DSM 7358 putative transmembrane anti-sigma factor YP_008731816.1 503747 D 1246995 CDS YP_008731817.1 556563392 17441121 complement(504506..504907) 1 NC_022657.1 pyridoxamine 5'-phosphate oxidase-like FMN-binding protein 504907 17441121 AFR_02375 Actinoplanes friuliensis DSM 7358 pyridoxamine 5'-phosphate oxidase-like FMN-binding protein YP_008731817.1 504506 R 1246995 CDS YP_008731818.1 556563393 17441122 504958..505572 1 NC_022657.1 COG1309 Transcriptional regulator; TetR family transcriptional regulator 505572 17441122 AFR_02380 Actinoplanes friuliensis DSM 7358 TetR family transcriptional regulator YP_008731818.1 504958 D 1246995 CDS YP_008731819.1 556563394 17441123 complement(505722..506132) 1 NC_022657.1 COG0607 Rhodanese-related sulfurtransferase; hypothetical protein 506132 17441123 AFR_02385 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731819.1 505722 R 1246995 CDS YP_008731820.1 556563395 17441124 complement(506126..506599) 1 NC_022657.1 putative cysteine dioxygenase 506599 17441124 AFR_02390 Actinoplanes friuliensis DSM 7358 putative cysteine dioxygenase YP_008731820.1 506126 R 1246995 CDS YP_008731821.1 556563396 17441125 complement(506890..508443) 1 NC_022657.1 COG0515 Serine/threonine protein kinase; Serine/threonine protein kinase 508443 17441125 AFR_02395 Actinoplanes friuliensis DSM 7358 Serine/threonine protein kinase YP_008731821.1 506890 R 1246995 CDS YP_008731822.1 556563397 17441126 508577..509707 1 NC_022657.1 COG0438 Glycosyltransferase; putative glycosyltransferase 509707 17441126 AFR_02400 Actinoplanes friuliensis DSM 7358 putative glycosyltransferase YP_008731822.1 508577 D 1246995 CDS YP_008731823.1 556563398 17441127 510285..511397 1 NC_022657.1 Liprin-alpha-3 511397 17441127 AFR_02405 Actinoplanes friuliensis DSM 7358 Liprin-alpha-3 YP_008731823.1 510285 D 1246995 CDS YP_008731824.1 556563399 17441128 511528..512037 1 NC_022657.1 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; putative RNA polymerase ECF-subfamily sigma factor 512037 17441128 AFR_02410 Actinoplanes friuliensis DSM 7358 putative RNA polymerase ECF-subfamily sigma factor YP_008731824.1 511528 D 1246995 CDS YP_008731825.1 556563400 17441129 512034..512738 1 NC_022657.1 hypothetical protein 512738 17441129 AFR_02415 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731825.1 512034 D 1246995 CDS YP_008731826.1 556563401 17441130 512795..513304 1 NC_022657.1 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; putative RNA polymerase ECF-subfamily sigma factor 513304 17441130 AFR_02420 Actinoplanes friuliensis DSM 7358 putative RNA polymerase ECF-subfamily sigma factor YP_008731826.1 512795 D 1246995 CDS YP_008731827.1 556563402 17441131 513307..514326 1 NC_022657.1 COG0516 IMP dehydrogenase/GMP reductase; hypothetical protein 514326 17441131 AFR_02425 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731827.1 513307 D 1246995 CDS YP_008731828.1 556563403 17441132 complement(514405..514782) 1 NC_022657.1 COG3011 Uncharacterized protein conserved in bacteria; hypothetical protein 514782 17441132 AFR_02430 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731828.1 514405 R 1246995 CDS YP_008731829.1 556563404 17441133 complement(514795..515811) 1 NC_022657.1 COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components; ribose transport system permease 515811 17441133 AFR_02435 Actinoplanes friuliensis DSM 7358 ribose transport system permease YP_008731829.1 514795 R 1246995 CDS YP_008731830.1 556563405 17441134 complement(515808..516779) 1 NC_022657.1 COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components; ribose transport system permease 516779 17441134 AFR_02440 Actinoplanes friuliensis DSM 7358 ribose transport system permease YP_008731830.1 515808 R 1246995 CDS YP_008731831.1 556563406 17441135 complement(516772..518307) 1 NC_022657.1 COG1129 ABC-type sugar transport system, ATPase component; ribose transport system ATP-binding protein 518307 17441135 AFR_02445 Actinoplanes friuliensis DSM 7358 ribose transport system ATP-binding protein YP_008731831.1 516772 R 1246995 CDS YP_008731832.1 556563407 17441136 complement(518403..521114) 1 NC_022657.1 COG3250 Beta-galactosidase/beta-glucuronidase; alpha-L-arabinofuranosidase B 521114 17441136 AFR_02450 Actinoplanes friuliensis DSM 7358 alpha-L-arabinofuranosidase B YP_008731832.1 518403 R 1246995 CDS YP_008731833.1 556563408 17441137 complement(521342..522427) 1 NC_022657.1 COG1879 ABC-type sugar transport system, periplasmic component; HTH-type transcriptional repressor purR 522427 17441137 AFR_02455 Actinoplanes friuliensis DSM 7358 HTH-type transcriptional repressor purR YP_008731833.1 521342 R 1246995 CDS YP_008731834.1 556563409 17441138 complement(522684..523592) 1 NC_022657.1 hypothetical protein 523592 17441138 AFR_02460 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731834.1 522684 R 1246995 CDS YP_008731835.1 556563410 17441139 complement(523589..523912) 1 NC_022657.1 hypothetical protein 523912 17441139 AFR_02465 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731835.1 523589 R 1246995 CDS YP_008731836.1 556563411 17441140 complement(523893..524870) 1 NC_022657.1 hypothetical protein 524870 17441140 AFR_02470 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731836.1 523893 R 1246995 CDS YP_008731837.1 556563412 17441141 complement(524867..525358) 1 NC_022657.1 hypothetical protein 525358 17441141 AFR_02475 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731837.1 524867 R 1246995 CDS YP_008731838.1 556563413 17441142 complement(525355..526083) 1 NC_022657.1 hypothetical protein 526083 17441142 AFR_02480 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731838.1 525355 R 1246995 CDS YP_008731839.1 556563414 17441143 complement(526204..527286) 1 NC_022657.1 hypothetical protein 527286 17441143 AFR_02485 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731839.1 526204 R 1246995 CDS YP_008731840.1 556563415 17441144 complement(527265..545522) 1 NC_022657.1 yd repeat-containing protein 545522 17441144 AFR_02490 Actinoplanes friuliensis DSM 7358 yd repeat-containing protein YP_008731840.1 527265 R 1246995 CDS YP_008731841.1 556563416 17441145 complement(547220..547675) 1 NC_022657.1 hypothetical protein 547675 17441145 AFR_02495 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731841.1 547220 R 1246995 CDS YP_008731842.1 556563417 17441146 547822..548103 1 NC_022657.1 hypothetical protein 548103 17441146 AFR_02500 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731842.1 547822 D 1246995 CDS YP_008731843.1 556563418 17441147 548137..548400 1 NC_022657.1 hypothetical protein 548400 17441147 AFR_02505 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731843.1 548137 D 1246995 CDS YP_008731844.1 556563419 17441148 complement(548706..549833) 1 NC_022657.1 hypothetical protein 549833 17441148 AFR_02510 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731844.1 548706 R 1246995 CDS YP_008731845.1 556563420 17441149 complement(549830..550246) 1 NC_022657.1 hypothetical protein 550246 17441149 AFR_02515 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731845.1 549830 R 1246995 CDS YP_008731846.1 556563421 17441150 550543..550851 1 NC_022657.1 COG4842 Uncharacterized protein conserved in bacteria; hypothetical protein 550851 17441150 AFR_02520 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731846.1 550543 D 1246995 CDS YP_008731847.1 556563422 17441151 550887..551189 1 NC_022657.1 COG4842 Uncharacterized protein conserved in bacteria; hypothetical protein 551189 17441151 AFR_02525 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731847.1 550887 D 1246995 CDS YP_008731848.1 556563423 17441152 551277..552107 1 NC_022657.1 hypothetical protein 552107 17441152 AFR_02530 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731848.1 551277 D 1246995 CDS YP_008731849.1 556563424 17441153 552176..556015 1 NC_022657.1 hypothetical protein 556015 17441153 AFR_02535 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731849.1 552176 D 1246995 CDS YP_008731850.1 556563425 17441154 555996..556337 1 NC_022657.1 hypothetical protein 556337 17441154 AFR_02540 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731850.1 555996 D 1246995 CDS YP_008731851.1 556563426 17441155 556334..560305 1 NC_022657.1 COG1674 DNA segregation ATPase FtsK/SpoIIIE and related proteins; cell division protein FtsK 560305 17441155 AFR_02545 Actinoplanes friuliensis DSM 7358 cell division protein FtsK YP_008731851.1 556334 D 1246995 CDS YP_008731852.1 556563427 17441156 560302..561711 1 NC_022657.1 hypothetical protein 561711 17441156 AFR_02550 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731852.1 560302 D 1246995 CDS YP_008731853.1 556563428 17441157 561718..563076 1 NC_022657.1 hypothetical protein 563076 17441157 AFR_02555 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731853.1 561718 D 1246995 CDS YP_008731854.1 556563429 17441158 563083..565710 1 NC_022657.1 hypothetical protein 565710 17441158 AFR_02560 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731854.1 563083 D 1246995 CDS YP_008731855.1 556563430 17441159 565727..569020 1 NC_022657.1 COG0464 ATPases of the AAA+ class; ATPase central domain-containing protein 569020 17441159 AFR_02565 Actinoplanes friuliensis DSM 7358 ATPase central domain-containing protein YP_008731855.1 565727 D 1246995 CDS YP_008731856.1 556563431 17441160 569070..569369 1 NC_022657.1 COG0718 Uncharacterized protein conserved in bacteria; hypothetical protein 569369 17441160 AFR_02570 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731856.1 569070 D 1246995 CDS YP_008731857.1 556563432 17441161 complement(569363..572821) 1 NC_022657.1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; SARP family transcriptional regulator 572821 17441161 AFR_02575 Actinoplanes friuliensis DSM 7358 SARP family transcriptional regulator YP_008731857.1 569363 R 1246995 CDS YP_008731858.1 556563433 17441162 complement(572877..575180) 1 NC_022657.1 COG3629 DNA-binding transcriptional activator of the SARP family; SARP family transcriptional regulator 575180 17441162 AFR_02580 Actinoplanes friuliensis DSM 7358 SARP family transcriptional regulator YP_008731858.1 572877 R 1246995 CDS YP_008731859.1 556563434 17441163 575609..575935 1 NC_022657.1 hypothetical protein 575935 17441163 AFR_02585 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731859.1 575609 D 1246995 CDS YP_008731860.1 556563435 17441164 576095..576718 1 NC_022657.1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; LuxR family transcriptional regulator 576718 17441164 AFR_02590 Actinoplanes friuliensis DSM 7358 LuxR family transcriptional regulator YP_008731860.1 576095 D 1246995 CDS YP_008731861.1 556563436 17441165 576744..579683 1 NC_022657.1 hypothetical protein 579683 17441165 AFR_02595 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731861.1 576744 D 1246995 CDS YP_008731862.1 556563437 17441166 580051..580239 1 NC_022657.1 hypothetical protein 580239 17441166 AFR_02600 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731862.1 580051 D 1246995 CDS YP_008731863.1 556563438 17441167 complement(580236..581303) 1 NC_022657.1 hypothetical protein 581303 17441167 AFR_02605 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731863.1 580236 R 1246995 CDS YP_008731864.1 556563439 17441168 complement(581224..583107) 1 NC_022657.1 COG1215 Glycosyltransferases, probably involved in cell wall biogenesis; group 2 family glycosyl transferase 583107 17441168 AFR_02610 Actinoplanes friuliensis DSM 7358 group 2 family glycosyl transferase YP_008731864.1 581224 R 1246995 CDS YP_008731865.1 556563440 17441169 583289..583771 1 NC_022657.1 COG1309 Transcriptional regulator; TetR family transcriptional regulator 583771 17441169 AFR_02615 Actinoplanes friuliensis DSM 7358 TetR family transcriptional regulator YP_008731865.1 583289 D 1246995 CDS YP_008731866.1 556563441 17441170 complement(583755..584798) 1 NC_022657.1 COG1619 Uncharacterized proteins, homologs of microcin C7 resistance protein MccF; hypothetical protein 584798 17441170 AFR_02620 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731866.1 583755 R 1246995 CDS YP_008731867.1 556563442 17441171 complement(584840..586327) 1 NC_022657.1 COG0477 Permeases of the major facilitator superfamily; drug resistance efflux protein 586327 17441171 AFR_02625 Actinoplanes friuliensis DSM 7358 drug resistance efflux protein YP_008731867.1 584840 R 1246995 CDS YP_008731868.1 556563443 17441172 complement(586369..587139) 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); short-chain dehydrogenase/reductase SDR 587139 17441172 AFR_02630 Actinoplanes friuliensis DSM 7358 short-chain dehydrogenase/reductase SDR YP_008731868.1 586369 R 1246995 CDS YP_008731869.1 556563444 17441173 complement(587190..587666) 1 NC_022657.1 COG0784 FOG: CheY-like receiver; response regulator mprA 587666 17441173 AFR_02635 Actinoplanes friuliensis DSM 7358 response regulator mprA YP_008731869.1 587190 R 1246995 CDS YP_008731870.1 556563445 17441174 587860..588129 1 NC_022657.1 COG1396 Predicted transcriptional regulators; helix-turn-helix domain-containing protein 588129 17441174 AFR_02640 Actinoplanes friuliensis DSM 7358 helix-turn-helix domain-containing protein YP_008731870.1 587860 D 1246995 CDS YP_008731871.1 556563446 17441175 588119..588361 1 NC_022657.1 COG3550 Uncharacterized protein related to capsule biosynthesis enzymes; HipA domain-containing protein 588361 17441175 AFR_02645 Actinoplanes friuliensis DSM 7358 HipA domain-containing protein YP_008731871.1 588119 D 1246995 CDS YP_008731872.1 556563447 17441176 589042..589308 1 NC_022657.1 hypothetical protein 589308 17441176 AFR_02650 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731872.1 589042 D 1246995 CDS YP_008731873.1 556563448 17441177 589378..591585 1 NC_022657.1 COG2199 FOG: GGDEF domain; putative signaling protein 591585 17441177 AFR_02655 Actinoplanes friuliensis DSM 7358 putative signaling protein YP_008731873.1 589378 D 1246995 CDS YP_008731874.1 556563449 17441178 complement(591590..591895) 1 NC_022657.1 COG1694 Predicted pyrophosphatase; hypothetical protein 591895 17441178 AFR_02660 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731874.1 591590 R 1246995 CDS YP_008731875.1 556563450 17441179 complement(591906..592955) 1 NC_022657.1 COG3980 Spore coat polysaccharide biosynthesis protein, predicted glycosyltransferase; hypothetical protein 592955 17441179 AFR_02665 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731875.1 591906 R 1246995 CDS YP_008731876.1 556563451 17441180 complement(592952..593686) 1 NC_022657.1 COG1861 Spore coat polysaccharide biosynthesis protein F, CMP-KDO synthetase homolog; putative acylneuraminate cytidylyltransferase 593686 17441180 AFR_02670 Actinoplanes friuliensis DSM 7358 putative acylneuraminate cytidylyltransferase YP_008731876.1 592952 R 1246995 CDS YP_008731877.1 556563452 17441181 complement(593692..595101) 1 NC_022657.1 hypothetical protein 595101 17441181 AFR_02675 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731877.1 593692 R 1246995 CDS YP_008731878.1 556563453 17441182 complement(595098..595922) 1 NC_022657.1 hypothetical protein 595922 17441182 AFR_02680 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731878.1 595098 R 1246995 CDS YP_008731879.1 556563454 17441183 complement(595927..597051) 1 NC_022657.1 COG0399 Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; putative aminotransferase 597051 17441183 AFR_02685 Actinoplanes friuliensis DSM 7358 putative aminotransferase YP_008731879.1 595927 R 1246995 CDS YP_008731880.1 556563455 17441184 complement(597051..598022) 1 NC_022657.1 COG1086 Predicted nucleoside-diphosphate sugar epimerases; putative polysaccharide biosynthesis protein 598022 17441184 AFR_02690 Actinoplanes friuliensis DSM 7358 putative polysaccharide biosynthesis protein YP_008731880.1 597051 R 1246995 CDS YP_008731881.1 556563456 17441185 598217..598462 1 NC_022657.1 COG0236 Acyl carrier protein; putative acyl carrier protein 598462 17441185 AFR_02695 Actinoplanes friuliensis DSM 7358 putative acyl carrier protein YP_008731881.1 598217 D 1246995 CDS YP_008731882.1 556563457 17441186 598455..599192 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); putative short-chain dehydrogenase 599192 17441186 AFR_02700 Actinoplanes friuliensis DSM 7358 putative short-chain dehydrogenase YP_008731882.1 598455 D 1246995 CDS YP_008731883.1 556563458 17441187 599189..600520 1 NC_022657.1 COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II; AMP-binding protein 600520 17441187 AFR_02705 Actinoplanes friuliensis DSM 7358 AMP-binding protein YP_008731883.1 599189 D 1246995 CDS YP_008731884.1 556563459 17441188 600517..601554 1 NC_022657.1 COG1541 Coenzyme F390 synthetase; putative acyl-protein synthetase 601554 17441188 AFR_02710 Actinoplanes friuliensis DSM 7358 putative acyl-protein synthetase YP_008731884.1 600517 D 1246995 CDS YP_008731885.1 556563460 17441189 601551..602735 1 NC_022657.1 putative acyl-CoA reductase 602735 17441189 AFR_02715 Actinoplanes friuliensis DSM 7358 putative acyl-CoA reductase YP_008731885.1 601551 D 1246995 CDS YP_008731886.1 556563461 17441190 602744..603727 1 NC_022657.1 COG0463 Glycosyltransferases involved in cell wall biogenesis; putative glycosyltransferase 603727 17441190 AFR_02720 Actinoplanes friuliensis DSM 7358 putative glycosyltransferase YP_008731886.1 602744 D 1246995 CDS YP_008731887.1 556563462 17441191 603724..605994 1 NC_022657.1 hypothetical protein 605994 17441191 AFR_02725 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731887.1 603724 D 1246995 CDS YP_008731888.1 556563463 17441192 complement(605979..606350) 1 NC_022657.1 alpha/beta hydrolase 606350 17441192 AFR_02730 Actinoplanes friuliensis DSM 7358 alpha/beta hydrolase YP_008731888.1 605979 R 1246995 CDS YP_008731889.1 556563464 17441193 complement(606347..606790) 1 NC_022657.1 COG2452 Predicted site-specific integrase-resolvase; excisionase/Xis, DNA-binding protein 606790 17441193 AFR_02735 Actinoplanes friuliensis DSM 7358 excisionase/Xis, DNA-binding protein YP_008731889.1 606347 R 1246995 CDS YP_008731890.1 556563465 17441194 complement(606834..607349) 1 NC_022657.1 COG1917 Uncharacterized conserved protein, contains double-stranded beta-helix domain; cupin 607349 17441194 AFR_02740 Actinoplanes friuliensis DSM 7358 cupin YP_008731890.1 606834 R 1246995 CDS YP_008731891.1 556563466 17441195 complement(607346..608275) 1 NC_022657.1 COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases; NADPH:quinone reductase-related Zn-dependent oxidoreductase 608275 17441195 AFR_02745 Actinoplanes friuliensis DSM 7358 NADPH:quinone reductase-related Zn-dependent oxidoreductase YP_008731891.1 607346 R 1246995 CDS YP_008731892.1 556563467 17441196 608388..608927 1 NC_022657.1 COG1846 Transcriptional regulators; MarR family transcriptional regulator 608927 17441196 AFR_02750 Actinoplanes friuliensis DSM 7358 MarR family transcriptional regulator YP_008731892.1 608388 D 1246995 CDS YP_008731893.1 556563468 17441197 complement(608754..610082) 1 NC_022657.1 COG0477 Permeases of the major facilitator superfamily; major facilitator superfamily protein 610082 17441197 AFR_02755 Actinoplanes friuliensis DSM 7358 major facilitator superfamily protein YP_008731893.1 608754 R 1246995 CDS YP_008731894.1 556563469 17441198 complement(610116..611216) 1 NC_022657.1 COG1680 Beta-lactamase class C and other penicillin binding proteins; beta-lactamase 611216 17441198 AFR_02760 Actinoplanes friuliensis DSM 7358 beta-lactamase YP_008731894.1 610116 R 1246995 CDS YP_008731895.1 556563470 17441199 611372..612685 1 NC_022657.1 COG4585 Signal transduction histidine kinase; Oxygen sensor histidine kinase nreB 612685 17441199 AFR_02765 Actinoplanes friuliensis DSM 7358 Oxygen sensor histidine kinase nreB YP_008731895.1 611372 D 1246995 CDS YP_008731896.1 556563471 17441200 612714..613358 1 NC_022657.1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; Response regulator gacA 613358 17441200 AFR_02770 Actinoplanes friuliensis DSM 7358 Response regulator gacA YP_008731896.1 612714 D 1246995 CDS YP_008731897.1 556563472 17441201 613355..613774 1 NC_022657.1 hypothetical protein 613774 17441201 AFR_02775 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731897.1 613355 D 1246995 CDS YP_008731898.1 556563473 17441202 613952..616036 1 NC_022657.1 COG2409 Predicted drug exporters of the RND superfamily; Membrane protein ydfJ 616036 17441202 AFR_02780 Actinoplanes friuliensis DSM 7358 Membrane protein ydfJ YP_008731898.1 613952 D 1246995 CDS YP_008731899.1 556563474 17441203 complement(616178..616351) 1 NC_022657.1 COG3237 Uncharacterized protein conserved in bacteria; CsbD family protein 616351 17441203 AFR_02785 Actinoplanes friuliensis DSM 7358 CsbD family protein YP_008731899.1 616178 R 1246995 CDS YP_008731900.1 556563475 17441204 complement(616407..618734) 1 NC_022657.1 COG2199 FOG: GGDEF domain; putative signaling protein 618734 17441204 AFR_02790 Actinoplanes friuliensis DSM 7358 putative signaling protein YP_008731900.1 616407 R 1246995 CDS YP_008731901.1 556563476 17441205 618893..619927 1 NC_022657.1 COG0463 Glycosyltransferases involved in cell wall biogenesis; putative glycosyltransferase 619927 17441205 AFR_02795 Actinoplanes friuliensis DSM 7358 putative glycosyltransferase YP_008731901.1 618893 D 1246995 CDS YP_008731902.1 556563477 17441206 619963..620430 1 NC_022657.1 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins; hypothetical protein 620430 17441206 AFR_02800 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731902.1 619963 D 1246995 CDS YP_008731903.1 556563478 17441207 620427..621467 1 NC_022657.1 COG2089 Sialic acid synthase; putative N-acetylneuraminic acid synthase 621467 17441207 AFR_02805 Actinoplanes friuliensis DSM 7358 putative N-acetylneuraminic acid synthase YP_008731903.1 620427 D 1246995 CDS YP_008731904.1 556563479 17441208 621486..623069 1 NC_022657.1 hypothetical protein 623069 17441208 AFR_02810 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731904.1 621486 D 1246995 CDS YP_008731905.1 556563480 17441209 623066..624019 1 NC_022657.1 hypothetical protein 624019 17441209 AFR_02815 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731905.1 623066 D 1246995 CDS YP_008731906.1 556563481 17441210 624016..625038 1 NC_022657.1 COG0360 Ribosomal protein S6; hypothetical protein 625038 17441210 AFR_02820 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731906.1 624016 D 1246995 CDS YP_008731907.1 556563482 17441211 625148..626587 1 NC_022657.1 putrescine oxidase 626587 17441211 AFR_02825 Actinoplanes friuliensis DSM 7358 putrescine oxidase YP_008731907.1 625148 D 1246995 CDS YP_008731908.1 556563483 17441212 626672..627058 1 NC_022657.1 COG0239 Integral membrane protein possibly involved in chromosome condensation; CrcB protein 627058 17441212 AFR_02830 Actinoplanes friuliensis DSM 7358 CrcB protein YP_008731908.1 626672 D 1246995 CDS YP_008731909.1 556563484 17441213 627055..627411 1 NC_022657.1 COG0239 Integral membrane protein possibly involved in chromosome condensation; putative CrcB-like protein 627411 17441213 AFR_02835 Actinoplanes friuliensis DSM 7358 putative CrcB-like protein YP_008731909.1 627055 D 1246995 CDS YP_008731910.1 556563485 17441214 627469..627945 1 NC_022657.1 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; ECF subfamily RNA polymerase sigma-24 factor 627945 17441214 AFR_02840 Actinoplanes friuliensis DSM 7358 ECF subfamily RNA polymerase sigma-24 factor YP_008731910.1 627469 D 1246995 CDS YP_008731911.1 556563486 17441215 627945..628988 1 NC_022657.1 hypothetical protein 628988 17441215 AFR_02845 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731911.1 627945 D 1246995 CDS YP_008731912.1 556563487 17441216 629038..629763 1 NC_022657.1 Polycystic kidney disease protein 1-like 3 629763 17441216 AFR_02850 Actinoplanes friuliensis DSM 7358 Polycystic kidney disease protein 1-like 3 YP_008731912.1 629038 D 1246995 CDS YP_008731913.1 556563488 17441217 complement(629749..632022) 1 NC_022657.1 COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain; putative diguanylate cyclase/phosphodiesterase with GAF sensor 632022 17441217 AFR_02855 Actinoplanes friuliensis DSM 7358 putative diguanylate cyclase/phosphodiesterase with GAF sensor YP_008731913.1 629749 R 1246995 CDS YP_008731914.1 556563489 17441218 632429..633190 1 NC_022657.1 COG1349 Transcriptional regulators of sugar metabolism; DeoR family transcriptional regulator 633190 17441218 AFR_02860 Actinoplanes friuliensis DSM 7358 DeoR family transcriptional regulator YP_008731914.1 632429 D 1246995 CDS YP_008731915.1 556563490 17441219 633272..634633 1 NC_022657.1 COG1653 ABC-type sugar transport system, periplasmic component; sugar ABC transporter solute-binding protein 634633 17441219 AFR_02865 Actinoplanes friuliensis DSM 7358 sugar ABC transporter solute-binding protein YP_008731915.1 633272 D 1246995 CDS YP_008731916.1 556563491 17441220 634691..635623 1 NC_022657.1 COG1175 ABC-type sugar transport systems, permease components; ABC transporter permease 635623 17441220 AFR_02870 Actinoplanes friuliensis DSM 7358 ABC transporter permease YP_008731916.1 634691 D 1246995 CDS YP_008731917.1 556563492 17441221 635620..636480 1 NC_022657.1 COG0395 ABC-type sugar transport system, permease component; sugar ABC transporter permease 636480 17441221 AFR_02875 Actinoplanes friuliensis DSM 7358 sugar ABC transporter permease YP_008731917.1 635620 D 1246995 CDS YP_008731918.1 556563493 17441222 636477..637466 1 NC_022657.1 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases; putative zinc-binding dehydrogenase 637466 17441222 AFR_02880 Actinoplanes friuliensis DSM 7358 putative zinc-binding dehydrogenase YP_008731918.1 636477 D 1246995 CDS YP_008731919.1 556563494 17441223 637591..639030 1 NC_022657.1 amino acid permease-associated protein 639030 17441223 AFR_02885 Actinoplanes friuliensis DSM 7358 amino acid permease-associated protein YP_008731919.1 637591 D 1246995 CDS YP_008731920.1 556563495 17441224 complement(639020..639496) 1 NC_022657.1 hypothetical protein 639496 17441224 AFR_02890 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731920.1 639020 R 1246995 CDS YP_008731921.1 556563496 17441225 639680..640120 1 NC_022657.1 COG1846 Transcriptional regulators; putative HTH-type transcriptional regulator 640120 17441225 AFR_02895 Actinoplanes friuliensis DSM 7358 putative HTH-type transcriptional regulator YP_008731921.1 639680 D 1246995 CDS YP_008731922.1 556563497 17441226 640146..641915 1 NC_022657.1 COG0477 Permeases of the major facilitator superfamily; yusP-like MFS-type transporter 641915 17441226 AFR_02900 Actinoplanes friuliensis DSM 7358 yusP-like MFS-type transporter YP_008731922.1 640146 D 1246995 CDS YP_008731923.1 556563498 17441227 complement(641905..642468) 1 NC_022657.1 COG1309 Transcriptional regulator; HTH-type transcriptional regulator betI 642468 17441227 AFR_02905 Actinoplanes friuliensis DSM 7358 HTH-type transcriptional regulator betI YP_008731923.1 641905 R 1246995 CDS YP_008731924.1 556563499 17441228 642571..643800 1 NC_022657.1 COG0477 Permeases of the major facilitator superfamily; Multidrug resistance protein mdtL 643800 17441228 AFR_02910 Actinoplanes friuliensis DSM 7358 Multidrug resistance protein mdtL YP_008731924.1 642571 D 1246995 CDS YP_008731925.1 556563500 17441229 643898..645493 1 NC_022657.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); putative tripeptidylaminopeptidase 645493 17441229 AFR_02915 Actinoplanes friuliensis DSM 7358 putative tripeptidylaminopeptidase YP_008731925.1 643898 D 1246995 CDS YP_008731926.1 556563501 17441230 complement(645503..646438) 1 NC_022657.1 COG0061 Predicted sugar kinase; ATP-nad/acox kinase 646438 17441230 AFR_02920 Actinoplanes friuliensis DSM 7358 ATP-nad/acox kinase YP_008731926.1 645503 R 1246995 CDS YP_008731927.1 556563502 17441231 646662..647252 1 NC_022657.1 COG2119 Predicted membrane protein; hypothetical protein 647252 17441231 AFR_02925 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731927.1 646662 D 1246995 CDS YP_008731928.1 556563503 17441232 647256..648212 1 NC_022657.1 COG1878 Predicted metal-dependent hydrolase; cyclase family protein 648212 17441232 AFR_02930 Actinoplanes friuliensis DSM 7358 cyclase family protein YP_008731928.1 647256 D 1246995 CDS YP_008731929.1 556563504 17441233 648209..648946 1 NC_022657.1 COG0457 FOG: TPR repeat; hypothetical protein 648946 17441233 AFR_02935 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731929.1 648209 D 1246995 CDS YP_008731930.1 556563505 17441234 648989..649708 1 NC_022657.1 COG0457 FOG: TPR repeat; hypothetical protein 649708 17441234 AFR_02940 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731930.1 648989 D 1246995 CDS YP_008731931.1 556563506 17441235 complement(649674..650702) 1 NC_022657.1 COG0392 Predicted integral membrane protein; hypothetical protein 650702 17441235 AFR_02945 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731931.1 649674 R 1246995 CDS YP_008731932.1 556563507 17441236 complement(650745..651902) 1 NC_022657.1 COG0823 Periplasmic component of the Tol biopolymer transport system; hypothetical protein 651902 17441236 AFR_02950 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731932.1 650745 R 1246995 CDS YP_008731933.1 556563508 17441237 complement(651899..652429) 1 NC_022657.1 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; RNA polymerase sigma-E factor 652429 17441237 AFR_02955 Actinoplanes friuliensis DSM 7358 RNA polymerase sigma-E factor YP_008731933.1 651899 R 1246995 CDS YP_008731934.1 556563509 17441238 652851..653918 1 NC_022657.1 COG2213 Phosphotransferase system, mannitol-specific IIBC component; PTS system mannitol-specific transporter subunit IIC 653918 17441238 AFR_02960 Actinoplanes friuliensis DSM 7358 PTS system mannitol-specific transporter subunit IIC YP_008731934.1 652851 D 1246995 CDS YP_008731935.1 556563510 17441239 653915..654235 1 NC_022657.1 COG2213 Phosphotransferase system, mannitol-specific IIBC component; PTS system lactose/cellobiose-specific transporter subunit IIB 654235 17441239 AFR_02965 Actinoplanes friuliensis DSM 7358 PTS system lactose/cellobiose-specific transporter subunit IIB YP_008731935.1 653915 D 1246995 CDS YP_008731936.1 556563511 17441240 654249..655001 1 NC_022657.1 COG2239 Mg/Co/Ni transporter MgtE (contains CBS domain); hypothetical protein 655001 17441240 AFR_02970 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731936.1 654249 D 1246995 CDS YP_008731937.1 556563512 17441241 655019..655450 1 NC_022657.1 COG4668 Mannitol/fructose-specific phosphotransferase system, IIA domain; phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2 655450 17441241 AFR_02975 Actinoplanes friuliensis DSM 7358 phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2 YP_008731937.1 655019 D 1246995 CDS YP_008731938.1 556563513 17441242 655447..655719 1 NC_022657.1 putative phosphocarrier protein HPr 655719 17441242 AFR_02980 Actinoplanes friuliensis DSM 7358 putative phosphocarrier protein HPr YP_008731938.1 655447 D 1246995 CDS YP_008731939.1 556563514 17441243 655712..657358 1 NC_022657.1 COG1080 Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria); putative phosphoenolpyruvate-protein phosphotransferase 657358 17441243 AFR_02985 Actinoplanes friuliensis DSM 7358 putative phosphoenolpyruvate-protein phosphotransferase YP_008731939.1 655712 D 1246995 CDS YP_008731940.1 556563515 17441244 657436..658371 1 NC_022657.1 COG4326 Sporulation control protein; Sporulation-control protein spo0M 658371 17441244 AFR_02990 Actinoplanes friuliensis DSM 7358 Sporulation-control protein spo0M YP_008731940.1 657436 D 1246995 CDS YP_008731941.1 556563516 17441245 658442..659761 1 NC_022657.1 COG1252 NADH dehydrogenase, FAD-containing subunit; NADH dehydrogenase 659761 17441245 AFR_02995 Actinoplanes friuliensis DSM 7358 NADH dehydrogenase YP_008731941.1 658442 D 1246995 CDS YP_008731942.1 556563517 17441246 659946..661400 1 NC_022657.1 COG0477 Permeases of the major facilitator superfamily; drug resistance transporter, EmrB/QacA subfamily protein 661400 17441246 AFR_03000 Actinoplanes friuliensis DSM 7358 drug resistance transporter, EmrB/QacA subfamily protein YP_008731942.1 659946 D 1246995 CDS YP_008731943.1 556563518 17441247 661548..662351 1 NC_022657.1 hypothetical protein 662351 17441247 AFR_03005 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731943.1 661548 D 1246995 CDS YP_008731944.1 556563519 17441248 complement(662348..663553) 1 NC_022657.1 COG3325 Chitinase; chitinase 663553 17441248 AFR_03010 Actinoplanes friuliensis DSM 7358 chitinase YP_008731944.1 662348 R 1246995 CDS YP_008731945.1 556563520 17441249 complement(663589..664074) 1 NC_022657.1 hypothetical protein 664074 17441249 AFR_03015 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731945.1 663589 R 1246995 CDS YP_008731946.1 556563521 17441250 664226..666334 1 NC_022657.1 COG1524 Uncharacterized proteins of the AP superfamily; putative phosphodiesterase/nucleotide pyrophosphatase 666334 17441250 AFR_03020 Actinoplanes friuliensis DSM 7358 putative phosphodiesterase/nucleotide pyrophosphatase YP_008731946.1 664226 D 1246995 CDS YP_008731947.1 556563522 17441251 666341..667486 1 NC_022657.1 hypothetical protein 667486 17441251 AFR_03025 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731947.1 666341 D 1246995 CDS YP_008731948.1 556563523 17441252 667727..668509 1 NC_022657.1 transposase is4 family protein 668509 17441252 AFR_03030 Actinoplanes friuliensis DSM 7358 transposase is4 family protein YP_008731948.1 667727 D 1246995 CDS YP_008731949.1 556563524 17441253 complement(669520..669834) 1 NC_022657.1 hypothetical protein 669834 17441253 AFR_03035 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731949.1 669520 R 1246995 CDS YP_008731950.1 556563525 17441254 669763..672489 1 NC_022657.1 COG3903 Predicted ATPase; transcriptional regulator, winged helix family protein 672489 17441254 AFR_03040 Actinoplanes friuliensis DSM 7358 transcriptional regulator, winged helix family protein YP_008731950.1 669763 D 1246995 CDS YP_008731951.1 556563526 17441255 complement(672486..673316) 1 NC_022657.1 COG0842 ABC-type multidrug transport system, permease component; ABC-2 type transporter 673316 17441255 AFR_03045 Actinoplanes friuliensis DSM 7358 ABC-2 type transporter YP_008731951.1 672486 R 1246995 CDS YP_008731952.1 556563527 17441256 complement(673313..674302) 1 NC_022657.1 COG1131 ABC-type multidrug transport system, ATPase component; daunorubicin resistance ABC transporter ATPase subunit 674302 17441256 AFR_03050 Actinoplanes friuliensis DSM 7358 daunorubicin resistance ABC transporter ATPase subunit YP_008731952.1 673313 R 1246995 CDS YP_008731953.1 556563528 17441257 complement(674348..675178) 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); putative short-chain dehydrogenase 675178 17441257 AFR_03055 Actinoplanes friuliensis DSM 7358 putative short-chain dehydrogenase YP_008731953.1 674348 R 1246995 CDS YP_008731954.1 556563529 17441258 complement(675180..676571) 1 NC_022657.1 COG2072 Predicted flavoprotein involved in K+ transport; FAD dependent oxidoreductase 676571 17441258 AFR_03060 Actinoplanes friuliensis DSM 7358 FAD dependent oxidoreductase YP_008731954.1 675180 R 1246995 CDS YP_008731955.1 556563530 17441259 676656..677597 1 NC_022657.1 COG2837 Predicted iron-dependent peroxidase; dyp-type peroxidase 677597 17441259 AFR_03065 Actinoplanes friuliensis DSM 7358 dyp-type peroxidase YP_008731955.1 676656 D 1246995 CDS YP_008731956.1 556563531 17441260 complement(677659..678192) 1 NC_022657.1 hypothetical protein 678192 17441260 AFR_03070 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731956.1 677659 R 1246995 CDS YP_008731957.1 556563532 17441261 complement(678251..678937) 1 NC_022657.1 COG0586 Uncharacterized membrane-associated protein; hypothetical protein 678937 17441261 AFR_03075 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731957.1 678251 R 1246995 CDS YP_008731958.1 556563533 17441262 complement(679091..681949) 1 NC_022657.1 COG3537 Putative alpha-1,2-mannosidase; hypothetical protein 681949 17441262 AFR_03080 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731958.1 679091 R 1246995 CDS YP_008731959.1 556563534 17441263 complement(682018..682371) 1 NC_022657.1 COG1793 ATP-dependent DNA ligase; ATP-dependent DNA ligase 682371 17441263 AFR_03085 Actinoplanes friuliensis DSM 7358 ATP-dependent DNA ligase YP_008731959.1 682018 R 1246995 CDS YP_008731960.1 556563535 17441264 682441..684159 1 NC_022657.1 hypothetical protein 684159 17441264 AFR_03090 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731960.1 682441 D 1246995 CDS YP_008731961.1 556563536 17441265 684247..684402 1 NC_022657.1 hypothetical protein 684402 17441265 AFR_03095 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731961.1 684247 D 1246995 CDS YP_008731962.1 556563537 17441266 complement(684447..685763) 1 NC_022657.1 COG0366 Glycosidases; cyclomaltodextrinase 685763 17441266 AFR_03100 Actinoplanes friuliensis DSM 7358 cyclomaltodextrinase YP_008731962.1 684447 R 1246995 CDS YP_008731963.1 556563538 17441267 complement(685846..686652) 1 NC_022657.1 COG1191 DNA-directed RNA polymerase specialized sigma subunit; RNA polymerase sigma factor rpoD 686652 17441267 AFR_03105 Actinoplanes friuliensis DSM 7358 RNA polymerase sigma factor rpoD YP_008731963.1 685846 R 1246995 CDS YP_008731964.1 556563539 17441268 complement(686885..687442) 1 NC_022657.1 COG2372 Uncharacterized protein, homolog of Cu resistance protein CopC; putative copper resistance protein CopC 687442 17441268 AFR_03110 Actinoplanes friuliensis DSM 7358 putative copper resistance protein CopC YP_008731964.1 686885 R 1246995 CDS YP_008731965.1 556563540 17441269 complement(687515..688030) 1 NC_022657.1 COG4894 Uncharacterized conserved protein; hypothetical protein 688030 17441269 AFR_03115 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731965.1 687515 R 1246995 CDS YP_008731966.1 556563541 17441270 complement(688058..689242) 1 NC_022657.1 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases; putative alcohol dehydrogenase 689242 17441270 AFR_03120 Actinoplanes friuliensis DSM 7358 putative alcohol dehydrogenase YP_008731966.1 688058 R 1246995 CDS YP_008731967.1 556563542 17441271 689312..690157 1 NC_022657.1 COG0300 Short-chain dehydrogenases of various substrate specificities; putative short-chain dehydrogenase 690157 17441271 AFR_03125 Actinoplanes friuliensis DSM 7358 putative short-chain dehydrogenase YP_008731967.1 689312 D 1246995 CDS YP_008731968.1 556563543 17441272 complement(690259..691080) 1 NC_022657.1 COG1396 Predicted transcriptional regulators; XRE family transcriptional regulator 691080 17441272 AFR_03130 Actinoplanes friuliensis DSM 7358 XRE family transcriptional regulator YP_008731968.1 690259 R 1246995 CDS YP_008731969.1 556563544 17441273 691384..692418 1 NC_022657.1 COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases); aryl-alcohol dehydrogenase 692418 17441273 AFR_03135 Actinoplanes friuliensis DSM 7358 aryl-alcohol dehydrogenase YP_008731969.1 691384 D 1246995 CDS YP_008731970.1 556563545 17441274 692619..695582 1 NC_022657.1 secreted protein 695582 17441274 AFR_03140 Actinoplanes friuliensis DSM 7358 secreted protein YP_008731970.1 692619 D 1246995 CDS YP_008731971.1 556563546 17441275 695697..697349 1 NC_022657.1 COG0840 Methyl-accepting chemotaxis protein; putative methyl-accepting chemotaxis protein 697349 17441275 AFR_03145 Actinoplanes friuliensis DSM 7358 putative methyl-accepting chemotaxis protein YP_008731971.1 695697 D 1246995 CDS YP_008731972.1 556563547 17441276 complement(697479..698312) 1 NC_022657.1 COG0030 Dimethyladenosine transferase (rRNA methylation); rRNA (adenine-N(6)-)-methyltransferase 698312 17441276 AFR_03150 Actinoplanes friuliensis DSM 7358 rRNA (adenine-N(6)-)-methyltransferase YP_008731972.1 697479 R 1246995 CDS YP_008731973.1 556563548 17441277 698612..699025 1 NC_022657.1 hypothetical protein 699025 17441277 AFR_03155 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731973.1 698612 D 1246995 CDS YP_008731974.1 556563549 17441278 complement(698996..700159) 1 NC_022657.1 major facilitator superfamily permease 700159 17441278 AFR_03160 Actinoplanes friuliensis DSM 7358 major facilitator superfamily permease YP_008731974.1 698996 R 1246995 CDS YP_008731975.1 556563550 17441279 700238..701194 1 NC_022657.1 ArsR family transcriptional regulator 701194 17441279 AFR_03165 Actinoplanes friuliensis DSM 7358 ArsR family transcriptional regulator YP_008731975.1 700238 D 1246995 CDS YP_008731976.1 556563551 17441280 701206..701958 1 NC_022657.1 COG0500 SAM-dependent methyltransferases; methyltransferase 701958 17441280 AFR_03170 Actinoplanes friuliensis DSM 7358 methyltransferase YP_008731976.1 701206 D 1246995 CDS YP_008731977.1 556563552 17441281 complement(701943..703505) 1 NC_022657.1 COG0025 NhaP-type Na+/H+ and K+/H+ antiporters; putative sodium/proton antiporter 703505 17441281 AFR_03175 Actinoplanes friuliensis DSM 7358 putative sodium/proton antiporter YP_008731977.1 701943 R 1246995 CDS YP_008731978.1 556563553 17441282 complement(703511..704416) 1 NC_022657.1 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain; transcriptional regulator, DeoR family protein 704416 17441282 AFR_03180 Actinoplanes friuliensis DSM 7358 transcriptional regulator, DeoR family protein YP_008731978.1 703511 R 1246995 CDS YP_008731979.1 556563554 17441283 704506..705264 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); acetoin reductase family protein 705264 17441283 AFR_03185 Actinoplanes friuliensis DSM 7358 acetoin reductase family protein YP_008731979.1 704506 D 1246995 CDS YP_008731980.1 556563555 17441284 705411..706832 1 NC_022657.1 COG0112 Glycine/serine hydroxymethyltransferase; serine hydroxymethyltransferase 706832 17441284 AFR_03190 Actinoplanes friuliensis DSM 7358 serine hydroxymethyltransferase YP_008731980.1 705411 D 1246995 CDS YP_008731981.1 556563556 17441285 706919..708013 1 NC_022657.1 COG3386 Gluconolactonase; hypothetical protein 708013 17441285 AFR_03195 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731981.1 706919 D 1246995 CDS YP_008731982.1 556563557 17441286 complement(708000..708503) 1 NC_022657.1 COG0622 Predicted phosphoesterase; calcineurin-like phosphoesterase 708503 17441286 AFR_03200 Actinoplanes friuliensis DSM 7358 calcineurin-like phosphoesterase YP_008731982.1 708000 R 1246995 CDS YP_008731983.1 556563558 17441287 709024..711246 1 NC_022657.1 COG3291 FOG: PKD repeat; Sialidase 711246 17441287 AFR_03205 Actinoplanes friuliensis DSM 7358 Sialidase YP_008731983.1 709024 D 1246995 CDS YP_008731984.1 556563559 17441288 complement(711230..712231) 1 NC_022657.1 COG1609 Transcriptional regulators; putative LacI-family transcriptional regulator 712231 17441288 AFR_03210 Actinoplanes friuliensis DSM 7358 putative LacI-family transcriptional regulator YP_008731984.1 711230 R 1246995 CDS YP_008731985.1 556563560 17441289 712408..713451 1 NC_022657.1 COG1879 ABC-type sugar transport system, periplasmic component; fructose transport system substrate-binding protein 713451 17441289 AFR_03215 Actinoplanes friuliensis DSM 7358 fructose transport system substrate-binding protein YP_008731985.1 712408 D 1246995 CDS YP_008731986.1 556563561 17441290 713454..714485 1 NC_022657.1 COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components; ABC transporter permease 714485 17441290 AFR_03220 Actinoplanes friuliensis DSM 7358 ABC transporter permease YP_008731986.1 713454 D 1246995 CDS YP_008731987.1 556563562 17441291 714482..715255 1 NC_022657.1 COG1129 ABC-type sugar transport system, ATPase component; putative ABC transporter ATP-binding protein 715255 17441291 AFR_03225 Actinoplanes friuliensis DSM 7358 putative ABC transporter ATP-binding protein YP_008731987.1 714482 D 1246995 CDS YP_008731988.1 556563563 17441292 complement(715308..716210) 1 NC_022657.1 COG2207 AraC-type DNA-binding domain-containing proteins; putative transcriptional regulator 716210 17441292 AFR_03230 Actinoplanes friuliensis DSM 7358 putative transcriptional regulator YP_008731988.1 715308 R 1246995 CDS YP_008731989.1 556563564 17441293 716302..717060 1 NC_022657.1 COG4922 Uncharacterized protein conserved in bacteria; hypothetical protein 717060 17441293 AFR_03235 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731989.1 716302 D 1246995 CDS YP_008731990.1 556563565 17441294 complement(717116..718282) 1 NC_022657.1 COG4952 Predicted sugar isomerase; L-rhamnose isomerase-like protein 718282 17441294 AFR_03240 Actinoplanes friuliensis DSM 7358 L-rhamnose isomerase-like protein YP_008731990.1 717116 R 1246995 CDS YP_008731991.1 556563566 17441295 complement(718288..718620) 1 NC_022657.1 COG3254 Uncharacterized conserved protein; hypothetical protein 718620 17441295 AFR_03245 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731991.1 718288 R 1246995 CDS YP_008731992.1 556563567 17441296 complement(718626..719699) 1 NC_022657.1 COG1879 ABC-type sugar transport system, periplasmic component; rhamnose ABC transporter periplasmic rhamnose- binding protein 719699 17441296 AFR_03250 Actinoplanes friuliensis DSM 7358 rhamnose ABC transporter periplasmic rhamnose- binding protein YP_008731992.1 718626 R 1246995 CDS YP_008731993.1 556563568 17441297 complement(719725..720714) 1 NC_022657.1 COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components; inner-membrane translocator 720714 17441297 AFR_03255 Actinoplanes friuliensis DSM 7358 inner-membrane translocator YP_008731993.1 719725 R 1246995 CDS YP_008731994.1 556563569 17441298 complement(720707..721729) 1 NC_022657.1 COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components; sugar ABC transporter permease 721729 17441298 AFR_03260 Actinoplanes friuliensis DSM 7358 sugar ABC transporter permease YP_008731994.1 720707 R 1246995 CDS YP_008731995.1 556563570 17441299 complement(721726..723249) 1 NC_022657.1 COG1129 ABC-type sugar transport system, ATPase component; sugar ABC transporter ATPase 723249 17441299 AFR_03265 Actinoplanes friuliensis DSM 7358 sugar ABC transporter ATPase YP_008731995.1 721726 R 1246995 CDS YP_008731996.1 556563571 17441300 723418..724452 1 NC_022657.1 COG1609 Transcriptional regulators; putative LacI-family transcriptional regulator 724452 17441300 AFR_03270 Actinoplanes friuliensis DSM 7358 putative LacI-family transcriptional regulator YP_008731996.1 723418 D 1246995 CDS YP_008731997.1 556563572 17441301 724565..726595 1 NC_022657.1 COG3347 Uncharacterized conserved protein; short chain dehydrogenase 726595 17441301 AFR_03275 Actinoplanes friuliensis DSM 7358 short chain dehydrogenase YP_008731997.1 724565 D 1246995 CDS YP_008731998.1 556563573 17441302 726592..728277 1 NC_022657.1 COG1070 Sugar (pentulose and hexulose) kinases; putative rhamnose kinase 728277 17441302 AFR_03280 Actinoplanes friuliensis DSM 7358 putative rhamnose kinase YP_008731998.1 726592 D 1246995 CDS YP_008731999.1 556563574 17441303 728279..729016 1 NC_022657.1 COG0247 Fe-S oxidoreductase; hypothetical protein 729016 17441303 AFR_03285 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008731999.1 728279 D 1246995 CDS YP_008732000.1 556563575 17441304 729013..730431 1 NC_022657.1 COG1139 Uncharacterized conserved protein containing a ferredoxin-like domain; hypothetical protein 730431 17441304 AFR_03290 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732000.1 729013 D 1246995 CDS YP_008732001.1 556563576 17441305 730443..731033 1 NC_022657.1 COG1556 Uncharacterized conserved protein; hypothetical protein 731033 17441305 AFR_03295 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732001.1 730443 D 1246995 CDS YP_008732002.1 556563577 17441306 731026..732447 1 NC_022657.1 L-arabinose isomerase 732447 17441306 AFR_03300 Actinoplanes friuliensis DSM 7358 L-arabinose isomerase YP_008732002.1 731026 D 1246995 CDS YP_008732003.1 556563578 17441307 732466..733323 1 NC_022657.1 COG0702 Predicted nucleoside-diphosphate-sugar epimerases; hypothetical protein 733323 17441307 AFR_03305 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732003.1 732466 D 1246995 CDS YP_008732004.1 556563579 17441308 733333..735783 1 NC_022657.1 COG2205 Osmosensitive K+ channel histidine kinase; putative two-component system sensor kinase for high-affinity potassium transport system 735783 17441308 AFR_03310 Actinoplanes friuliensis DSM 7358 putative two-component system sensor kinase for high-affinity potassium transport system YP_008732004.1 733333 D 1246995 CDS YP_008732005.1 556563580 17441309 735886..736506 1 NC_022657.1 COG1309 Transcriptional regulator; putative TetR-family transcriptional regulator 736506 17441309 AFR_03315 Actinoplanes friuliensis DSM 7358 putative TetR-family transcriptional regulator YP_008732005.1 735886 D 1246995 CDS YP_008732006.1 556563581 17441310 736508..737401 1 NC_022657.1 COG1131 ABC-type multidrug transport system, ATPase component; putative ABC transporter ATP-binding protein 737401 17441310 AFR_03320 Actinoplanes friuliensis DSM 7358 putative ABC transporter ATP-binding protein YP_008732006.1 736508 D 1246995 CDS YP_008732007.1 556563582 17441311 737398..738996 1 NC_022657.1 COG3559 Putative exporter of polyketide antibiotics; hypothetical protein 738996 17441311 AFR_03325 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732007.1 737398 D 1246995 CDS YP_008732008.1 556563583 17441312 complement(739042..740694) 1 NC_022657.1 COG0025 NhaP-type Na+/H+ and K+/H+ antiporters; putative sodium/proton antiporter 740694 17441312 AFR_03330 Actinoplanes friuliensis DSM 7358 putative sodium/proton antiporter YP_008732008.1 739042 R 1246995 CDS YP_008732009.1 556563584 17441313 complement(740794..742254) 1 NC_022657.1 COG0499 S-adenosylhomocysteine hydrolase; S-adenosyl-L-homocysteine hydrolase 742254 17441313 AFR_03335 Actinoplanes friuliensis DSM 7358 S-adenosyl-L-homocysteine hydrolase YP_008732009.1 740794 R 1246995 CDS YP_008732010.1 556563585 17441314 complement(742381..743496) 1 NC_022657.1 COG5285 Protein involved in biosynthesis of mitomycin antibiotics/polyketide fumonisin; Phytanoyl-CoA dioxygenase 743496 17441314 AFR_03340 Actinoplanes friuliensis DSM 7358 Phytanoyl-CoA dioxygenase YP_008732010.1 742381 R 1246995 CDS YP_008732011.1 556563586 17441315 743570..744607 1 NC_022657.1 COG1609 Transcriptional regulators; LacI family transcriptional regulator 744607 17441315 AFR_03345 Actinoplanes friuliensis DSM 7358 LacI family transcriptional regulator YP_008732011.1 743570 D 1246995 CDS YP_008732012.1 556563587 17441316 744691..745014 1 NC_022657.1 COG3795 Uncharacterized protein conserved in bacteria; hypothetical protein 745014 17441316 AFR_03350 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732012.1 744691 D 1246995 CDS YP_008732013.1 556563588 17441317 745015..746196 1 NC_022657.1 COG4941 Predicted RNA polymerase sigma factor containing a TPR repeat domain; hypothetical protein 746196 17441317 AFR_03355 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732013.1 745015 D 1246995 CDS YP_008732014.1 556563589 17441318 746203..746703 1 NC_022657.1 pyridoxamine 5'-phosphate oxidase-related FMN- binding protein 746703 17441318 AFR_03360 Actinoplanes friuliensis DSM 7358 pyridoxamine 5'-phosphate oxidase-related FMN- binding protein YP_008732014.1 746203 D 1246995 CDS YP_008732015.1 556563590 17441319 complement(746688..747494) 1 NC_022657.1 COG1082 Sugar phosphate isomerases/epimerases; 2-keto-myo-inositol dehydratase 747494 17441319 AFR_03365 Actinoplanes friuliensis DSM 7358 2-keto-myo-inositol dehydratase YP_008732015.1 746688 R 1246995 CDS YP_008732016.1 556563591 17441320 complement(747533..748534) 1 NC_022657.1 COG0673 Predicted dehydrogenases and related proteins; oxidoreductase domain-containing protein 748534 17441320 AFR_03370 Actinoplanes friuliensis DSM 7358 oxidoreductase domain-containing protein YP_008732016.1 747533 R 1246995 CDS YP_008732017.1 556563592 17441321 complement(748537..749298) 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); short chain dehydrogenase 749298 17441321 AFR_03375 Actinoplanes friuliensis DSM 7358 short chain dehydrogenase YP_008732017.1 748537 R 1246995 CDS YP_008732018.1 556563593 17441322 749486..750598 1 NC_022657.1 COG0501 Zn-dependent protease with chaperone function; peptidase M48 Ste24p 750598 17441322 AFR_03380 Actinoplanes friuliensis DSM 7358 peptidase M48 Ste24p YP_008732018.1 749486 D 1246995 CDS YP_008732019.1 556563594 17441323 750755..751219 1 NC_022657.1 COG0242 N-formylmethionyl-tRNA deformylase; peptide deformylase 751219 17441323 AFR_03385 Actinoplanes friuliensis DSM 7358 peptide deformylase YP_008732019.1 750755 D 1246995 CDS YP_008732020.1 556563595 17441324 751209..751709 1 NC_022657.1 COG0500 SAM-dependent methyltransferases; methyltransferase type 12 751709 17441324 AFR_03390 Actinoplanes friuliensis DSM 7358 methyltransferase type 12 YP_008732020.1 751209 D 1246995 CDS YP_008732021.1 556563596 17441325 complement(751823..753022) 1 NC_022657.1 COG2124 Cytochrome P450; cytochrome P450 753022 17441325 AFR_03395 Actinoplanes friuliensis DSM 7358 cytochrome P450 YP_008732021.1 751823 R 1246995 CDS YP_008732022.1 556563597 17441326 753236..753661 1 NC_022657.1 COG1396 Predicted transcriptional regulators; hypothetical protein 753661 17441326 AFR_03400 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732022.1 753236 D 1246995 CDS YP_008732023.1 556563598 17441327 complement(753668..754828) 1 NC_022657.1 hypothetical protein 754828 17441327 AFR_03405 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732023.1 753668 R 1246995 CDS YP_008732024.1 556563599 17441328 complement(754825..755199) 1 NC_022657.1 COG0519 GMP synthase, PP-ATPase domain/subunit; Cinorf13 protein 755199 17441328 AFR_03410 Actinoplanes friuliensis DSM 7358 Cinorf13 protein YP_008732024.1 754825 R 1246995 CDS YP_008732025.1 556563600 17441329 complement(755393..756619) 1 NC_022657.1 COG3004 Na+/H+ antiporter; Na(+)/H(+) antiporter nhaA 1 756619 17441329 AFR_03415 Actinoplanes friuliensis DSM 7358 Na(+)/H(+) antiporter nhaA 1 YP_008732025.1 755393 R 1246995 CDS YP_008732026.1 556563601 17441330 complement(756695..757534) 1 NC_022657.1 hypothetical protein 757534 17441330 AFR_03420 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732026.1 756695 R 1246995 CDS YP_008732027.1 556563602 17441331 complement(757531..758445) 1 NC_022657.1 COG1131 ABC-type multidrug transport system, ATPase component; ABC transporter 758445 17441331 AFR_03425 Actinoplanes friuliensis DSM 7358 ABC transporter YP_008732027.1 757531 R 1246995 CDS YP_008732028.1 556563603 17441332 758591..759802 1 NC_022657.1 COG4585 Signal transduction histidine kinase; histidine kinase 759802 17441332 AFR_03430 Actinoplanes friuliensis DSM 7358 histidine kinase YP_008732028.1 758591 D 1246995 CDS YP_008732029.1 556563604 17441333 759799..760476 1 NC_022657.1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; LuxR family transcriptional regulator 760476 17441333 AFR_03435 Actinoplanes friuliensis DSM 7358 LuxR family transcriptional regulator YP_008732029.1 759799 D 1246995 CDS YP_008732030.1 556563605 17441334 760473..761336 1 NC_022657.1 integral membrane protein 761336 17441334 AFR_03440 Actinoplanes friuliensis DSM 7358 integral membrane protein YP_008732030.1 760473 D 1246995 CDS YP_008732031.1 556563606 17441335 complement(761263..762495) 1 NC_022657.1 COG0477 Permeases of the major facilitator superfamily; yfiS-like MFS-type transporter 762495 17441335 AFR_03445 Actinoplanes friuliensis DSM 7358 yfiS-like MFS-type transporter YP_008732031.1 761263 R 1246995 CDS YP_008732032.1 556563607 17441336 complement(762485..763024) 1 NC_022657.1 COG0640 Predicted transcriptional regulators; regulatory protein ArsR 763024 17441336 AFR_03450 Actinoplanes friuliensis DSM 7358 regulatory protein ArsR YP_008732032.1 762485 R 1246995 CDS YP_008732033.1 556563608 17441337 763118..764539 1 NC_022657.1 COG0840 Methyl-accepting chemotaxis protein; Methyl-accepting chemotaxis protein mcpB 764539 17441337 AFR_03455 Actinoplanes friuliensis DSM 7358 Methyl-accepting chemotaxis protein mcpB YP_008732033.1 763118 D 1246995 CDS YP_008732034.1 556563609 17441338 complement(764549..765565) 1 NC_022657.1 hypothetical protein 765565 17441338 AFR_03460 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732034.1 764549 R 1246995 CDS YP_008732035.1 556563610 17441339 complement(765565..768687) 1 NC_022657.1 COG0060 Isoleucyl-tRNA synthetase; isoleucyl-tRNA ligase 768687 ileS 17441339 ileS Actinoplanes friuliensis DSM 7358 isoleucyl-tRNA ligase YP_008732035.1 765565 R 1246995 CDS YP_008732036.1 556563611 17441340 complement(768958..769578) 1 NC_022657.1 COG0009 Putative translation factor (SUA5); hypothetical protein 769578 17441340 AFR_03470 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732036.1 768958 R 1246995 CDS YP_008732037.1 556563612 17441341 complement(769588..769992) 1 NC_022657.1 hypothetical protein 769992 17441341 AFR_03475 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732037.1 769588 R 1246995 CDS YP_008732038.1 556563613 17441342 770062..770502 1 NC_022657.1 COG1846 Transcriptional regulators; transcriptional regulator 770502 17441342 AFR_03480 Actinoplanes friuliensis DSM 7358 transcriptional regulator YP_008732038.1 770062 D 1246995 CDS YP_008732039.1 556563614 17441343 770583..772463 1 NC_022657.1 COG0719 ABC-type transport system involved in Fe-S cluster assembly, permease component; hypothetical protein 772463 17441343 AFR_03485 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732039.1 770583 D 1246995 CDS YP_008732040.1 556563615 17441344 772521..773927 1 NC_022657.1 COG2199 FOG: GGDEF domain; hypothetical protein 773927 17441344 AFR_03490 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732040.1 772521 D 1246995 CDS YP_008732041.1 556563616 17441345 complement(773924..774499) 1 NC_022657.1 COG0431 Predicted flavoprotein; NADPH-dependent FMN reductase 774499 17441345 AFR_03495 Actinoplanes friuliensis DSM 7358 NADPH-dependent FMN reductase YP_008732041.1 773924 R 1246995 CDS YP_008732042.1 556563617 17441346 complement(774504..774950) 1 NC_022657.1 COG1846 Transcriptional regulators; MarR family transcriptional regulator 774950 17441346 AFR_03500 Actinoplanes friuliensis DSM 7358 MarR family transcriptional regulator YP_008732042.1 774504 R 1246995 CDS YP_008732043.1 556563618 17441347 775039..777258 1 NC_022657.1 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases; FAD linked oxidase domain-containing protein 777258 17441347 AFR_03505 Actinoplanes friuliensis DSM 7358 FAD linked oxidase domain-containing protein YP_008732043.1 775039 D 1246995 CDS YP_008732044.1 556563619 17441348 777255..778181 1 NC_022657.1 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases; luciferase-like monooxygenase 778181 17441348 AFR_03510 Actinoplanes friuliensis DSM 7358 luciferase-like monooxygenase YP_008732044.1 777255 D 1246995 CDS YP_008732045.1 556563620 17441349 complement(778195..779322) 1 NC_022657.1 COG0332 3-oxoacyl-[acyl-carrier-protein] synthase III; putative beta-ketoacyl-acyl carrier protein synthase 779322 17441349 AFR_03515 Actinoplanes friuliensis DSM 7358 putative beta-ketoacyl-acyl carrier protein synthase YP_008732045.1 778195 R 1246995 CDS YP_008732046.1 556563621 17441350 779449..780765 1 NC_022657.1 COG2771 DNA-binding HTH domain-containing proteins; hypothetical protein 780765 17441350 AFR_03520 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732046.1 779449 D 1246995 CDS YP_008732047.1 556563622 17441351 780795..781763 1 NC_022657.1 COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases; oxidoreductase 781763 17441351 AFR_03525 Actinoplanes friuliensis DSM 7358 oxidoreductase YP_008732047.1 780795 D 1246995 CDS YP_008732048.1 556563623 17441352 781903..783909 1 NC_022657.1 hypothetical protein 783909 17441352 AFR_03530 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732048.1 781903 D 1246995 CDS YP_008732049.1 556563624 17441353 783980..784783 1 NC_022657.1 COG3217 Uncharacterized Fe-S protein; hypothetical protein 784783 17441353 AFR_03535 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732049.1 783980 D 1246995 CDS YP_008732050.1 556563625 17441354 784816..785169 1 NC_022657.1 COG0640 Predicted transcriptional regulators; regulatory protein ArsR 785169 17441354 AFR_03540 Actinoplanes friuliensis DSM 7358 regulatory protein ArsR YP_008732050.1 784816 D 1246995 CDS YP_008732051.1 556563626 17441355 785166..785627 1 NC_022657.1 COG3832 Uncharacterized conserved protein; hypothetical protein 785627 17441355 AFR_03545 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732051.1 785166 D 1246995 CDS YP_008732052.1 556563627 17441356 785644..786030 1 NC_022657.1 hypothetical protein 786030 17441356 AFR_03550 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732052.1 785644 D 1246995 CDS YP_008732053.1 556563628 17441357 complement(786049..786606) 1 NC_022657.1 COG0262 Dihydrofolate reductase; hypothetical protein 786606 17441357 AFR_03555 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732053.1 786049 R 1246995 CDS YP_008732054.1 556563629 17441358 786715..787851 1 NC_022657.1 COG0673 Predicted dehydrogenases and related proteins; oxidoreductase 787851 17441358 AFR_03560 Actinoplanes friuliensis DSM 7358 oxidoreductase YP_008732054.1 786715 D 1246995 CDS YP_008732055.1 556563630 17441359 complement(787848..788528) 1 NC_022657.1 COG1309 Transcriptional regulator; TetR family transcriptional regulator 788528 17441359 AFR_03565 Actinoplanes friuliensis DSM 7358 TetR family transcriptional regulator YP_008732055.1 787848 R 1246995 CDS YP_008732056.1 556563631 17441360 788614..789351 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); short chain dehydrogenase 789351 17441360 AFR_03570 Actinoplanes friuliensis DSM 7358 short chain dehydrogenase YP_008732056.1 788614 D 1246995 CDS YP_008732057.1 556563632 17441361 complement(789367..790131) 1 NC_022657.1 nucleoporin 790131 17441361 AFR_03575 Actinoplanes friuliensis DSM 7358 nucleoporin YP_008732057.1 789367 R 1246995 CDS YP_008732058.1 556563633 17441362 complement(790220..790531) 1 NC_022657.1 hypothetical protein 790531 17441362 AFR_03580 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732058.1 790220 R 1246995 CDS YP_008732059.1 556563634 17441363 complement(790598..791260) 1 NC_022657.1 COG3544 Uncharacterized protein conserved in bacteria; hypothetical protein 791260 17441363 AFR_03585 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732059.1 790598 R 1246995 CDS YP_008732060.1 556563635 17441364 791392..792831 1 NC_022657.1 COG5276 Uncharacterized conserved protein; hypothetical protein 792831 17441364 AFR_03590 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732060.1 791392 D 1246995 CDS YP_008732061.1 556563636 17441365 792901..793485 1 NC_022657.1 COG0500 SAM-dependent methyltransferases; hypothetical protein 793485 17441365 AFR_03595 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732061.1 792901 D 1246995 CDS YP_008732062.1 556563637 17441366 complement(793498..794316) 1 NC_022657.1 COG1388 FOG: LysM repeat; hypothetical protein 794316 17441366 AFR_03600 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732062.1 793498 R 1246995 CDS YP_008732063.1 556563638 17441367 complement(794420..794722) 1 NC_022657.1 hypothetical protein 794722 17441367 AFR_03605 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732063.1 794420 R 1246995 CDS YP_008732064.1 556563639 17441368 complement(794719..795123) 1 NC_022657.1 hypothetical protein 795123 17441368 AFR_03610 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732064.1 794719 R 1246995 CDS YP_008732065.1 556563640 17441369 795380..796315 1 NC_022657.1 Monocyte differentiation antigen CD14 796315 17441369 AFR_03615 Actinoplanes friuliensis DSM 7358 Monocyte differentiation antigen CD14 YP_008732065.1 795380 D 1246995 CDS YP_008732066.1 556563641 17441370 796319..797269 1 NC_022657.1 hypothetical protein 797269 17441370 AFR_03620 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732066.1 796319 D 1246995 CDS YP_008732067.1 556563642 17441371 797271..798347 1 NC_022657.1 COG0189 Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase); hypothetical protein 798347 17441371 AFR_03625 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732067.1 797271 D 1246995 CDS YP_008732068.1 556563643 17441372 798335..799138 1 NC_022657.1 COG2194 Predicted membrane-associated, metal-dependent hydrolase; hypothetical protein 799138 17441372 AFR_03630 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732068.1 798335 D 1246995 CDS YP_008732069.1 556563644 17441373 799135..800442 1 NC_022657.1 COG0635 Coproporphyrinogen III oxidase and related Fe-S oxidoreductases; coproporphyrinogen III oxidase 800442 17441373 AFR_03635 Actinoplanes friuliensis DSM 7358 coproporphyrinogen III oxidase YP_008732069.1 799135 D 1246995 CDS YP_008732070.1 556563645 17441374 800439..801320 1 NC_022657.1 hypothetical protein 801320 17441374 AFR_03640 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732070.1 800439 D 1246995 CDS YP_008732071.1 556563646 17441375 801338..801841 1 NC_022657.1 COG0225 Peptide methionine sulfoxide reductase; methionine sulfoxide reductase A 801841 17441375 AFR_03645 Actinoplanes friuliensis DSM 7358 methionine sulfoxide reductase A YP_008732071.1 801338 D 1246995 CDS YP_008732072.1 556563647 17441376 complement(801998..802957) 1 NC_022657.1 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; RNA polymerase factor sigma-70 802957 17441376 AFR_03650 Actinoplanes friuliensis DSM 7358 RNA polymerase factor sigma-70 YP_008732072.1 801998 R 1246995 CDS YP_008732073.1 556563648 17441377 803028..803399 1 NC_022657.1 hypothetical protein 803399 17441377 AFR_03655 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732073.1 803028 D 1246995 CDS YP_008732074.1 556563649 17441378 complement(803389..804561) 1 NC_022657.1 COG3344 Retron-type reverse transcriptase; hypothetical protein 804561 17441378 AFR_03660 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732074.1 803389 R 1246995 CDS YP_008732075.1 556563650 17441379 804853..805203 1 NC_022657.1 hypothetical protein 805203 17441379 AFR_03665 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732075.1 804853 D 1246995 CDS YP_008732076.1 556563651 17441380 805274..806128 1 NC_022657.1 cell wall anchor domain-containing protein 806128 17441380 AFR_03670 Actinoplanes friuliensis DSM 7358 cell wall anchor domain-containing protein YP_008732076.1 805274 D 1246995 CDS YP_008732077.1 556563652 17441381 806272..808323 1 NC_022657.1 COG2866 Predicted carboxypeptidase; putative carboxypeptidase 808323 17441381 AFR_03675 Actinoplanes friuliensis DSM 7358 putative carboxypeptidase YP_008732077.1 806272 D 1246995 CDS YP_008732078.1 556563653 17441382 complement(808361..809539) 1 NC_022657.1 COG2931 RTX toxins and related Ca2+-binding proteins; hypothetical protein 809539 17441382 AFR_03680 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732078.1 808361 R 1246995 CDS YP_008732079.1 556563654 17441383 complement(809566..812643) 1 NC_022657.1 COG2133 Glucose/sorbosone dehydrogenases; hypothetical protein 812643 17441383 AFR_03685 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732079.1 809566 R 1246995 CDS YP_008732080.1 556563655 17441384 813138..820862 1 NC_022657.1 COG3209 Rhs family protein; YD repeat-containing protein 820862 17441384 AFR_03690 Actinoplanes friuliensis DSM 7358 YD repeat-containing protein YP_008732080.1 813138 D 1246995 CDS YP_008732081.1 556563656 17441385 820859..821287 1 NC_022657.1 hypothetical protein 821287 17441385 AFR_03695 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732081.1 820859 D 1246995 CDS YP_008732082.1 556563657 17441386 complement(821848..824742) 1 NC_022657.1 hypothetical protein 824742 17441386 AFR_03700 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732082.1 821848 R 1246995 CDS YP_008732083.1 556563658 17441387 825351..833024 1 NC_022657.1 COG3209 Rhs family protein; YD repeat-containing protein 833024 17441387 AFR_03705 Actinoplanes friuliensis DSM 7358 YD repeat-containing protein YP_008732083.1 825351 D 1246995 CDS YP_008732084.1 556563659 17441388 833055..833588 1 NC_022657.1 hypothetical protein 833588 17441388 AFR_03710 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732084.1 833055 D 1246995 CDS YP_008732085.1 556563660 17441389 833597..833995 1 NC_022657.1 COG1117 ABC-type phosphate transport system, ATPase component; hypothetical protein 833995 17441389 AFR_03715 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732085.1 833597 D 1246995 CDS YP_008732086.1 556563661 17441390 833983..834621 1 NC_022657.1 COG1350 Predicted alternative tryptophan synthase beta-subunit (paralog of TrpB); hypothetical protein 834621 17441390 AFR_03720 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732086.1 833983 D 1246995 CDS YP_008732087.1 556563662 17441391 complement(834607..835209) 1 NC_022657.1 COG1309 Transcriptional regulator; TetR family transcriptional regulator 835209 17441391 AFR_03725 Actinoplanes friuliensis DSM 7358 TetR family transcriptional regulator YP_008732087.1 834607 R 1246995 CDS YP_008732088.1 556563663 17441392 835267..836196 1 NC_022657.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); alpha/beta hydrolase fold protein 836196 17441392 AFR_03730 Actinoplanes friuliensis DSM 7358 alpha/beta hydrolase fold protein YP_008732088.1 835267 D 1246995 CDS YP_008732089.1 556563664 17441393 complement(836096..837082) 1 NC_022657.1 COG2207 AraC-type DNA-binding domain-containing proteins; AraC family transcriptional regulator 837082 17441393 AFR_03735 Actinoplanes friuliensis DSM 7358 AraC family transcriptional regulator YP_008732089.1 836096 R 1246995 CDS YP_008732090.1 556563665 17441394 complement(837096..837851) 1 NC_022657.1 COG0702 Predicted nucleoside-diphosphate-sugar epimerases; hypothetical protein 837851 17441394 AFR_03740 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732090.1 837096 R 1246995 CDS YP_008732091.1 556563666 17441395 838060..839682 1 NC_022657.1 COG1132 ABC-type multidrug transport system, ATPase and permease components; putative ABC transporter ATPase and permease protein 839682 17441395 AFR_03745 Actinoplanes friuliensis DSM 7358 putative ABC transporter ATPase and permease protein YP_008732091.1 838060 D 1246995 CDS YP_008732092.1 556563667 17441396 839679..841400 1 NC_022657.1 COG1132 ABC-type multidrug transport system, ATPase and permease components; putative ABC transporter ATPase and permease protein 841400 17441396 AFR_03750 Actinoplanes friuliensis DSM 7358 putative ABC transporter ATPase and permease protein YP_008732092.1 839679 D 1246995 CDS YP_008732093.1 556563668 17441397 complement(841397..842368) 1 NC_022657.1 COG2378 Predicted transcriptional regulator; helix-turn-helix type 11 domain-containing protein 842368 17441397 AFR_03755 Actinoplanes friuliensis DSM 7358 helix-turn-helix type 11 domain-containing protein YP_008732093.1 841397 R 1246995 CDS YP_008732094.1 556563669 17441398 842432..842827 1 NC_022657.1 COG0251 Putative translation initiation inhibitor, yjgF family; endoribonuclease L-PSP 842827 17441398 AFR_03760 Actinoplanes friuliensis DSM 7358 endoribonuclease L-PSP YP_008732094.1 842432 D 1246995 CDS YP_008732095.1 556563670 17441399 complement(842829..843353) 1 NC_022657.1 hypothetical protein 843353 17441399 AFR_03765 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732095.1 842829 R 1246995 CDS YP_008732096.1 556563671 17441400 843594..844019 1 NC_022657.1 hypothetical protein 844019 17441400 AFR_03770 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732096.1 843594 D 1246995 CDS YP_008732097.1 556563672 17441401 844250..844717 1 NC_022657.1 hypothetical protein 844717 17441401 AFR_03775 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732097.1 844250 D 1246995 CDS YP_008732098.1 556563673 17441402 complement(844771..845379) 1 NC_022657.1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; transcriptional regulatory protein uhpA 845379 17441402 AFR_03780 Actinoplanes friuliensis DSM 7358 transcriptional regulatory protein uhpA YP_008732098.1 844771 R 1246995 CDS YP_008732099.1 556563674 17441403 complement(845461..846300) 1 NC_022657.1 Polycystic kidney disease protein 1-like 3 846300 17441403 AFR_03785 Actinoplanes friuliensis DSM 7358 Polycystic kidney disease protein 1-like 3 YP_008732099.1 845461 R 1246995 CDS YP_008732100.1 556563675 17441404 846443..846904 1 NC_022657.1 COG0823 Periplasmic component of the Tol biopolymer transport system; hypothetical protein 846904 17441404 AFR_03790 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732100.1 846443 D 1246995 CDS YP_008732101.1 556563676 17441405 847194..848288 1 NC_022657.1 COG3693 Beta-1,4-xylanase; endo-1,4-beta-xylanase 848288 17441405 AFR_03795 Actinoplanes friuliensis DSM 7358 endo-1,4-beta-xylanase YP_008732101.1 847194 D 1246995 CDS YP_008732102.1 556563677 17441407 complement(848528..849403) 1 NC_022657.1 COG0582 Integrase; integrase 849403 17441407 AFR_03800 Actinoplanes friuliensis DSM 7358 integrase YP_008732102.1 848528 R 1246995 CDS YP_008732103.1 556563678 17441408 851130..851546 1 NC_022657.1 hypothetical protein 851546 17441408 AFR_03805 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732103.1 851130 D 1246995 CDS YP_008732104.1 556563679 17441409 complement(851602..853161) 1 NC_022657.1 COG0583 Transcriptional regulator; LysR family transcriptional regulator 853161 17441409 AFR_03810 Actinoplanes friuliensis DSM 7358 LysR family transcriptional regulator YP_008732104.1 851602 R 1246995 CDS YP_008732105.1 556563680 17441410 853232..853591 1 NC_022657.1 hypothetical protein 853591 17441410 AFR_03815 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732105.1 853232 D 1246995 CDS YP_008732106.1 556563681 17441411 complement(853578..854630) 1 NC_022657.1 hypothetical protein 854630 17441411 AFR_03820 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732106.1 853578 R 1246995 CDS YP_008732107.1 556563682 17441412 complement(854630..855745) 1 NC_022657.1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; LuxR family transcriptional regulator 855745 17441412 AFR_03825 Actinoplanes friuliensis DSM 7358 LuxR family transcriptional regulator YP_008732107.1 854630 R 1246995 CDS YP_008732108.1 556563683 17441413 complement(855742..855978) 1 NC_022657.1 COG2771 DNA-binding HTH domain-containing proteins; LuxR family transcriptional regulator 855978 17441413 AFR_03830 Actinoplanes friuliensis DSM 7358 LuxR family transcriptional regulator YP_008732108.1 855742 R 1246995 CDS YP_008732109.1 556563684 17441414 856373..856543 1 NC_022657.1 hypothetical protein 856543 17441414 AFR_03835 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732109.1 856373 D 1246995 CDS YP_008732110.1 556563685 17441415 856768..857130 1 NC_022657.1 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); anti-anti-sigma factor 857130 17441415 AFR_03840 Actinoplanes friuliensis DSM 7358 anti-anti-sigma factor YP_008732110.1 856768 D 1246995 CDS YP_008732111.1 556563686 17441416 857287..857655 1 NC_022657.1 COG0642 Signal transduction histidine kinase; hypothetical protein 857655 17441416 AFR_03845 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732111.1 857287 D 1246995 CDS YP_008732112.1 556563687 17441417 857726..858094 1 NC_022657.1 hypothetical protein 858094 17441417 AFR_03850 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732112.1 857726 D 1246995 CDS YP_008732113.1 556563688 17441418 complement(858113..859057) 1 NC_022657.1 COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases; putative alcohol dehydrogenase 859057 17441418 AFR_03855 Actinoplanes friuliensis DSM 7358 putative alcohol dehydrogenase YP_008732113.1 858113 R 1246995 CDS YP_008732114.1 556563689 17441419 complement(859057..859416) 1 NC_022657.1 COG0692 Uracil DNA glycosylase; hypothetical protein 859416 17441419 AFR_03860 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732114.1 859057 R 1246995 CDS YP_008732115.1 556563690 17441420 complement(859413..860276) 1 NC_022657.1 COG3384 Uncharacterized conserved protein; putative ring-cleavage dioxygenase 860276 17441420 AFR_03865 Actinoplanes friuliensis DSM 7358 putative ring-cleavage dioxygenase YP_008732115.1 859413 R 1246995 CDS YP_008732116.1 556563691 17441421 complement(860285..861064) 1 NC_022657.1 COG0372 Citrate synthase; hypothetical protein 861064 17441421 AFR_03870 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732116.1 860285 R 1246995 CDS YP_008732117.1 556563692 17441422 complement(861046..862170) 1 NC_022657.1 COG1804 Predicted acyl-CoA transferases/carnitine dehydratase; putative CoA-transferase family III protein 862170 17441422 AFR_03875 Actinoplanes friuliensis DSM 7358 putative CoA-transferase family III protein YP_008732117.1 861046 R 1246995 CDS YP_008732118.1 556563693 17441423 862370..863800 1 NC_022657.1 COG0402 Cytosine deaminase and related metal-dependent hydrolases; putative amidohydrolase 863800 17441423 AFR_03880 Actinoplanes friuliensis DSM 7358 putative amidohydrolase YP_008732118.1 862370 D 1246995 CDS YP_008732119.1 556563694 17441424 863841..864638 1 NC_022657.1 COG1414 Transcriptional regulator; putative IclR-family transcriptional regulator 864638 17441424 AFR_03885 Actinoplanes friuliensis DSM 7358 putative IclR-family transcriptional regulator YP_008732119.1 863841 D 1246995 CDS YP_008732120.1 556563695 17441425 864709..865320 1 NC_022657.1 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins; putative GCN5-related N-acetyltransferase 865320 17441425 AFR_03890 Actinoplanes friuliensis DSM 7358 putative GCN5-related N-acetyltransferase YP_008732120.1 864709 D 1246995 CDS YP_008732121.1 556563696 17441426 865333..866424 1 NC_022657.1 hypothetical protein 866424 17441426 AFR_03895 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732121.1 865333 D 1246995 CDS YP_008732122.1 556563697 17441427 complement(867435..868118) 1 NC_022657.1 COG0500 SAM-dependent methyltransferases; methyltransferase 868118 17441427 AFR_03900 Actinoplanes friuliensis DSM 7358 methyltransferase YP_008732122.1 867435 R 1246995 CDS YP_008732123.1 556563698 17441428 complement(868452..869828) 1 NC_022657.1 COG1228 Imidazolonepropionase and related amidohydrolases; amidohydrolase-family protein 869828 17441428 AFR_03905 Actinoplanes friuliensis DSM 7358 amidohydrolase-family protein YP_008732123.1 868452 R 1246995 CDS YP_008732124.1 556563699 17441429 869895..870467 1 NC_022657.1 COG1309 Transcriptional regulator; TetR family transcriptional regulator 870467 17441429 AFR_03910 Actinoplanes friuliensis DSM 7358 TetR family transcriptional regulator YP_008732124.1 869895 D 1246995 CDS YP_008732125.1 556563700 17441430 complement(870469..870768) 1 NC_022657.1 hypothetical protein 870768 17441430 AFR_03915 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732125.1 870469 R 1246995 CDS YP_008732126.1 556563701 17441431 complement(870888..872120) 1 NC_022657.1 COG0463 Glycosyltransferases involved in cell wall biogenesis; glycosyl transferase family protein 872120 17441431 AFR_03920 Actinoplanes friuliensis DSM 7358 glycosyl transferase family protein YP_008732126.1 870888 R 1246995 CDS YP_008732127.1 556563702 17441432 complement(872258..874363) 1 NC_022657.1 COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family; glycosyl transferase 874363 17441432 AFR_03925 Actinoplanes friuliensis DSM 7358 glycosyl transferase YP_008732127.1 872258 R 1246995 CDS YP_008732128.1 556563703 17441433 complement(874464..875525) 1 NC_022657.1 COG0722 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase; phospho-2-dehydro-3-deoxyheptonate aldolase 875525 17441433 AFR_03930 Actinoplanes friuliensis DSM 7358 phospho-2-dehydro-3-deoxyheptonate aldolase YP_008732128.1 874464 R 1246995 CDS YP_008732129.1 556563704 17441434 875804..876211 1 NC_022657.1 hypothetical protein 876211 17441434 AFR_03935 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732129.1 875804 D 1246995 CDS YP_008732130.1 556563705 17441435 complement(876212..877756) 1 NC_022657.1 COG0642 Signal transduction histidine kinase; putative two-component system sensor kinase 877756 17441435 AFR_03940 Actinoplanes friuliensis DSM 7358 putative two-component system sensor kinase YP_008732130.1 876212 R 1246995 CDS YP_008732131.1 556563706 17441436 complement(877734..878465) 1 NC_022657.1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; putative two-component system response regulator 878465 17441436 AFR_03945 Actinoplanes friuliensis DSM 7358 putative two-component system response regulator YP_008732131.1 877734 R 1246995 CDS YP_008732132.1 556563707 17441437 878570..878863 1 NC_022657.1 hypothetical protein 878863 17441437 AFR_03950 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732132.1 878570 D 1246995 CDS YP_008732133.1 556563708 17441438 878930..880546 1 NC_022657.1 COG5184 Alpha-tubulin suppressor and related RCC1 domain-containing proteins; Protein sidekick-2 880546 17441438 AFR_03955 Actinoplanes friuliensis DSM 7358 Protein sidekick-2 YP_008732133.1 878930 D 1246995 CDS YP_008732134.1 556563709 17441439 complement(880533..882692) 1 NC_022657.1 hypothetical protein 882692 17441439 AFR_03960 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732134.1 880533 R 1246995 CDS YP_008732135.1 556563710 17441440 882829..883200 1 NC_022657.1 COG0457 FOG: TPR repeat; hypothetical protein 883200 17441440 AFR_03965 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732135.1 882829 D 1246995 CDS YP_008732136.1 556563711 17441441 883211..883495 1 NC_022657.1 COG1193 Mismatch repair ATPase (MutS family); Smr protein/MutS2 883495 17441441 AFR_03970 Actinoplanes friuliensis DSM 7358 Smr protein/MutS2 YP_008732136.1 883211 D 1246995 CDS YP_008732137.1 556563712 17441442 complement(883605..885962) 1 NC_022657.1 COG2234 Predicted aminopeptidases; putative M28-family peptidase 885962 17441442 AFR_03975 Actinoplanes friuliensis DSM 7358 putative M28-family peptidase YP_008732137.1 883605 R 1246995 CDS YP_008732138.1 556563713 17441443 886067..886414 1 NC_022657.1 hypothetical protein 886414 17441443 AFR_03980 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732138.1 886067 D 1246995 CDS YP_008732139.1 556563714 17441444 886563..887753 1 NC_022657.1 COG0784 FOG: CheY-like receiver; putative magnesium/manganase-dependent protein phosphatase with response regulator receiver domain 887753 17441444 AFR_03985 Actinoplanes friuliensis DSM 7358 putative magnesium/manganase-dependent protein phosphatase with response regulator receiver domain YP_008732139.1 886563 D 1246995 CDS YP_008732140.1 556563715 17441445 887750..889345 1 NC_022657.1 COG0642 Signal transduction histidine kinase; putative two-component system sensor kinase 889345 17441445 AFR_03990 Actinoplanes friuliensis DSM 7358 putative two-component system sensor kinase YP_008732140.1 887750 D 1246995 CDS YP_008732141.1 556563716 17441446 889342..889797 1 NC_022657.1 COG0784 FOG: CheY-like receiver; putative response regulator receiver domain protein 889797 17441446 AFR_03995 Actinoplanes friuliensis DSM 7358 putative response regulator receiver domain protein YP_008732141.1 889342 D 1246995 CDS YP_008732142.1 556563717 17441447 889790..890596 1 NC_022657.1 COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family; putative inositol monophosphatase 890596 17441447 AFR_04000 Actinoplanes friuliensis DSM 7358 putative inositol monophosphatase YP_008732142.1 889790 D 1246995 CDS YP_008732143.1 556563718 17441448 complement(890593..890940) 1 NC_022657.1 COG2764 Uncharacterized protein conserved in bacteria; glyoxalase/bleomycin resistance protein/dioxygenase 890940 17441448 AFR_04005 Actinoplanes friuliensis DSM 7358 glyoxalase/bleomycin resistance protein/dioxygenase YP_008732143.1 890593 R 1246995 CDS YP_008732144.1 556563719 17441449 890965..891738 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); putative short-chain dehydrogenase 891738 17441449 AFR_04010 Actinoplanes friuliensis DSM 7358 putative short-chain dehydrogenase YP_008732144.1 890965 D 1246995 CDS YP_008732145.1 556563720 17441450 891803..892813 1 NC_022657.1 hypothetical protein 892813 17441450 AFR_04015 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732145.1 891803 D 1246995 CDS YP_008732146.1 556563721 17441451 892841..894352 1 NC_022657.1 COG0421 Spermidine synthase; hypothetical protein 894352 17441451 AFR_04020 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732146.1 892841 D 1246995 CDS YP_008732147.1 556563722 17441452 894454..896172 1 NC_022657.1 COG0515 Serine/threonine protein kinase; putative serine/threonine protein kinase 896172 17441452 AFR_04025 Actinoplanes friuliensis DSM 7358 putative serine/threonine protein kinase YP_008732147.1 894454 D 1246995 CDS YP_008732148.1 556563723 17441453 complement(896169..896891) 1 NC_022657.1 COG0569 K+ transport systems, NAD-binding component; putative cation transporter 896891 17441453 AFR_04030 Actinoplanes friuliensis DSM 7358 putative cation transporter YP_008732148.1 896169 R 1246995 CDS YP_008732149.1 556563724 17441454 complement(896884..898224) 1 NC_022657.1 COG0168 Trk-type K+ transport systems, membrane components; putative cation transporter 898224 17441454 AFR_04035 Actinoplanes friuliensis DSM 7358 putative cation transporter YP_008732149.1 896884 R 1246995 CDS YP_008732150.1 556563725 17441455 898408..899628 1 NC_022657.1 COG0477 Permeases of the major facilitator superfamily; major facilitator transporter 899628 17441455 AFR_04040 Actinoplanes friuliensis DSM 7358 major facilitator transporter YP_008732150.1 898408 D 1246995 CDS YP_008732151.1 556563726 17441456 899625..900227 1 NC_022657.1 COG0500 SAM-dependent methyltransferases; type 11 methyltransferase 900227 17441456 AFR_04045 Actinoplanes friuliensis DSM 7358 type 11 methyltransferase YP_008732151.1 899625 D 1246995 CDS YP_008732152.1 556563727 17441457 900519..901229 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); putative short-chain dehydrogenase 901229 17441457 AFR_04050 Actinoplanes friuliensis DSM 7358 putative short-chain dehydrogenase YP_008732152.1 900519 D 1246995 CDS YP_008732153.1 556563728 17441458 complement(901238..901507) 1 NC_022657.1 hypothetical protein 901507 17441458 AFR_04055 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732153.1 901238 R 1246995 CDS YP_008732154.1 556563729 17441459 complement(901689..902087) 1 NC_022657.1 hypothetical protein 902087 17441459 AFR_04060 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732154.1 901689 R 1246995 CDS YP_008732155.1 556563730 17441460 902212..904368 1 NC_022657.1 COG0514 Superfamily II DNA helicase; ATP-dependent DNA helicase RecQ 904368 17441460 AFR_04065 Actinoplanes friuliensis DSM 7358 ATP-dependent DNA helicase RecQ YP_008732155.1 902212 D 1246995 CDS YP_008732156.1 556563731 17441461 complement(904812..905783) 1 NC_022657.1 COG0791 Cell wall-associated hydrolases (invasion-associated proteins); NLP/P60 protein 905783 17441461 AFR_04070 Actinoplanes friuliensis DSM 7358 NLP/P60 protein YP_008732156.1 904812 R 1246995 CDS YP_008732157.1 556563732 17441462 905849..906151 1 NC_022657.1 COG1937 Uncharacterized protein conserved in bacteria; Copper-sensing transcriptional repressor csoR 906151 17441462 AFR_04075 Actinoplanes friuliensis DSM 7358 Copper-sensing transcriptional repressor csoR YP_008732157.1 905849 D 1246995 CDS YP_008732158.1 556563733 17441463 906166..906378 1 NC_022657.1 COG2608 Copper chaperone; Cation-transporting ATPase pacS 906378 17441463 AFR_04080 Actinoplanes friuliensis DSM 7358 Cation-transporting ATPase pacS YP_008732158.1 906166 D 1246995 CDS YP_008732159.1 556563734 17441464 906371..907360 1 NC_022657.1 hypothetical protein 907360 17441464 AFR_04085 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732159.1 906371 D 1246995 CDS YP_008732160.1 556563735 17441465 complement(907363..908499) 1 NC_022657.1 COG0500 SAM-dependent methyltransferases; Glutathione S-transferase C-terminal domain-containing protein 908499 17441465 AFR_04090 Actinoplanes friuliensis DSM 7358 Glutathione S-transferase C-terminal domain-containing protein YP_008732160.1 907363 R 1246995 CDS YP_008732161.1 556563736 17441466 908588..909229 1 NC_022657.1 COG5398 Heme oxygenase; putative heme oxygenase 909229 17441466 AFR_04095 Actinoplanes friuliensis DSM 7358 putative heme oxygenase YP_008732161.1 908588 D 1246995 CDS YP_008732162.1 556563737 17441467 909226..909519 1 NC_022657.1 COG0748 Putative heme iron utilization protein; hypothetical protein 909519 17441467 AFR_04100 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732162.1 909226 D 1246995 CDS YP_008732163.1 556563738 17441468 complement(909659..911473) 1 NC_022657.1 COG0513 Superfamily II DNA and RNA helicases; putative DEAD/DEAH box helicase 911473 17441468 AFR_04105 Actinoplanes friuliensis DSM 7358 putative DEAD/DEAH box helicase YP_008732163.1 909659 R 1246995 CDS YP_008732164.1 556563739 17441469 complement(911734..911958) 1 NC_022657.1 hypothetical protein 911958 17441469 AFR_04110 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732164.1 911734 R 1246995 CDS YP_008732165.1 556563740 17441470 complement(911996..912556) 1 NC_022657.1 COG1309 Transcriptional regulator; TetR family transcriptional regulator 912556 17441470 AFR_04115 Actinoplanes friuliensis DSM 7358 TetR family transcriptional regulator YP_008732165.1 911996 R 1246995 CDS YP_008732166.1 556563741 17441471 912812..914851 1 NC_022657.1 Protein Daple 914851 17441471 AFR_04120 Actinoplanes friuliensis DSM 7358 Protein Daple YP_008732166.1 912812 D 1246995 CDS YP_008732167.1 556563742 17441472 914851..915810 1 NC_022657.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); alpha/beta hydrolase fold protein 915810 17441472 AFR_04125 Actinoplanes friuliensis DSM 7358 alpha/beta hydrolase fold protein YP_008732167.1 914851 D 1246995 CDS YP_008732168.1 556563743 17441473 915888..916757 1 NC_022657.1 COG0015 Adenylosuccinate lyase; hypothetical protein 916757 17441473 AFR_04130 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732168.1 915888 D 1246995 CDS YP_008732169.1 556563744 17441474 complement(916767..918737) 1 NC_022657.1 hypothetical protein 918737 17441474 AFR_04135 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732169.1 916767 R 1246995 CDS YP_008732170.1 556563745 17441475 919873..921054 1 NC_022657.1 hypothetical protein 921054 17441475 AFR_04140 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732170.1 919873 D 1246995 CDS YP_008732171.1 556563746 17441476 921168..922349 1 NC_022657.1 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2; molybdopterin biosynthesis-like protein MoeZ 922349 17441476 AFR_04145 Actinoplanes friuliensis DSM 7358 molybdopterin biosynthesis-like protein MoeZ YP_008732171.1 921168 D 1246995 CDS YP_008732172.1 556563747 17441477 922497..923306 1 NC_022657.1 hypothetical protein 923306 17441477 AFR_04150 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732172.1 922497 D 1246995 CDS YP_008732173.1 556563748 17441478 complement(923446..924684) 1 NC_022657.1 COG0014 Gamma-glutamyl phosphate reductase; gamma-glutamyl phosphate reductase 924684 proA 17441478 proA Actinoplanes friuliensis DSM 7358 gamma-glutamyl phosphate reductase YP_008732173.1 923446 R 1246995 CDS YP_008732174.1 556563749 17441479 complement(924740..925861) 1 NC_022657.1 COG0263 Glutamate 5-kinase; glutamate 5-kinase 925861 17441479 AFR_04160 Actinoplanes friuliensis DSM 7358 glutamate 5-kinase YP_008732174.1 924740 R 1246995 CDS YP_008732175.1 556563750 17441480 925905..926216 1 NC_022657.1 COG3695 Predicted methylated DNA-protein cysteine methyltransferase; putative 6-O-methylguanine DNA methyltransferase 926216 17441480 AFR_04165 Actinoplanes friuliensis DSM 7358 putative 6-O-methylguanine DNA methyltransferase YP_008732175.1 925905 D 1246995 CDS YP_008732176.1 556563751 17441481 926216..927016 1 NC_022657.1 COG3315 O-Methyltransferase involved in polyketide biosynthesis; hypothetical protein 927016 17441481 AFR_04170 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732176.1 926216 D 1246995 CDS YP_008732177.1 556563752 17441482 complement(927007..927690) 1 NC_022657.1 COG1309 Transcriptional regulator; putative TetR-family transcriptional regulator 927690 17441482 AFR_04175 Actinoplanes friuliensis DSM 7358 putative TetR-family transcriptional regulator YP_008732177.1 927007 R 1246995 CDS YP_008732178.1 556563753 17441483 927793..928722 1 NC_022657.1 COG0451 Nucleoside-diphosphate-sugar epimerases; putative NAD-dependent epimerase/dehydratase 928722 17441483 AFR_04180 Actinoplanes friuliensis DSM 7358 putative NAD-dependent epimerase/dehydratase YP_008732178.1 927793 D 1246995 CDS YP_008732179.1 556563754 17441484 complement(928715..930064) 1 NC_022657.1 COG0405 Gamma-glutamyltransferase; gamma-glutamyltranspeptidase 930064 17441484 AFR_04185 Actinoplanes friuliensis DSM 7358 gamma-glutamyltranspeptidase YP_008732179.1 928715 R 1246995 CDS YP_008732180.1 556563755 17441485 930189..931508 1 NC_022657.1 COG2211 Na+/melibiose symporter and related transporters; putative MFS transporter 931508 17441485 AFR_04190 Actinoplanes friuliensis DSM 7358 putative MFS transporter YP_008732180.1 930189 D 1246995 CDS YP_008732181.1 556563756 17441486 931505..932428 1 NC_022657.1 COG3173 Predicted aminoglycoside phosphotransferase; aminoglycoside phosphotransferase 932428 17441486 AFR_04195 Actinoplanes friuliensis DSM 7358 aminoglycoside phosphotransferase YP_008732181.1 931505 D 1246995 CDS YP_008732182.1 556563757 17441487 932471..933145 1 NC_022657.1 COG2045 Phosphosulfolactate phosphohydrolase and related enzymes; 2-phosphosulfolactate phosphatase 933145 17441487 AFR_04200 Actinoplanes friuliensis DSM 7358 2-phosphosulfolactate phosphatase YP_008732182.1 932471 D 1246995 CDS YP_008732183.1 556563758 17441488 933155..934606 1 NC_022657.1 COG0076 Glutamate decarboxylase and related PLP-dependent proteins; pyridoxal-dependent decarboxylase 934606 17441488 AFR_04205 Actinoplanes friuliensis DSM 7358 pyridoxal-dependent decarboxylase YP_008732183.1 933155 D 1246995 CDS YP_008732184.1 556563759 17441489 934623..935183 1 NC_022657.1 COG0377 NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases; NADH-quinone oxidoreductase subunit B 935183 17441489 AFR_04210 Actinoplanes friuliensis DSM 7358 NADH-quinone oxidoreductase subunit B YP_008732184.1 934623 D 1246995 CDS YP_008732185.1 556563760 17441490 935234..936538 1 NC_022657.1 COG4320 Uncharacterized protein conserved in bacteria; hypothetical protein 936538 17441490 AFR_04215 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732185.1 935234 D 1246995 CDS YP_008732186.1 556563761 17441491 complement(936543..937553) 1 NC_022657.1 COG1080 Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria); hypothetical protein 937553 17441491 AFR_04220 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732186.1 936543 R 1246995 CDS YP_008732187.1 556563762 17441492 complement(937546..938043) 1 NC_022657.1 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; putative RNA polymerase ECF-subfamily sigma factor 938043 17441492 AFR_04225 Actinoplanes friuliensis DSM 7358 putative RNA polymerase ECF-subfamily sigma factor YP_008732187.1 937546 R 1246995 CDS YP_008732188.1 556563763 17441493 938181..939275 1 NC_022657.1 COG0852 NADH:ubiquinone oxidoreductase 27 kD subunit; putative NADH dehydrogenase I chain C 939275 17441493 AFR_04230 Actinoplanes friuliensis DSM 7358 putative NADH dehydrogenase I chain C YP_008732188.1 938181 D 1246995 CDS YP_008732189.1 556563764 17441494 939275..940234 1 NC_022657.1 COG1005 NADH:ubiquinone oxidoreductase subunit 1 (chain H); putative NADH dehydrogenase I chain H 940234 17441494 AFR_04235 Actinoplanes friuliensis DSM 7358 putative NADH dehydrogenase I chain H YP_008732189.1 939275 D 1246995 CDS YP_008732190.1 556563765 17441495 940342..941439 1 NC_022657.1 COG1680 Beta-lactamase class C and other penicillin binding proteins; D-alanyl-D-alanine carboxypeptidase 941439 17441495 AFR_04240 Actinoplanes friuliensis DSM 7358 D-alanyl-D-alanine carboxypeptidase YP_008732190.1 940342 D 1246995 CDS YP_008732191.1 556563766 17441496 complement(941487..941903) 1 NC_022657.1 hypothetical protein 941903 17441496 AFR_04245 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732191.1 941487 R 1246995 CDS YP_008732192.1 556563767 17441497 942137..942721 1 NC_022657.1 COG1143 Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I); NADH dehydrogenase I subunit I 942721 17441497 AFR_04250 Actinoplanes friuliensis DSM 7358 NADH dehydrogenase I subunit I YP_008732192.1 942137 D 1246995 CDS YP_008732193.1 556563768 17441498 942718..943245 1 NC_022657.1 COG0839 NADH:ubiquinone oxidoreductase subunit 6 (chain J); NADH dehydrogenase I subunit J 943245 17441498 AFR_04255 Actinoplanes friuliensis DSM 7358 NADH dehydrogenase I subunit J YP_008732193.1 942718 D 1246995 CDS YP_008732194.1 556563769 17441499 943245..943622 1 NC_022657.1 COG0713 NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K); putative NADH dehydrogenase I chain K 943622 17441499 AFR_04260 Actinoplanes friuliensis DSM 7358 putative NADH dehydrogenase I chain K YP_008732194.1 943245 D 1246995 CDS YP_008732195.1 556563770 17441500 943619..945520 1 NC_022657.1 COG1009 NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit; putative NADH dehydrogenase I chain L 945520 17441500 AFR_04265 Actinoplanes friuliensis DSM 7358 putative NADH dehydrogenase I chain L YP_008732195.1 943619 D 1246995 CDS YP_008732196.1 556563771 17441501 945517..947064 1 NC_022657.1 COG1008 NADH:ubiquinone oxidoreductase subunit 4 (chain M); putative NADH dehydrogenase I chain M 947064 17441501 AFR_04270 Actinoplanes friuliensis DSM 7358 putative NADH dehydrogenase I chain M YP_008732196.1 945517 D 1246995 CDS YP_008732197.1 556563772 17441502 947061..948527 1 NC_022657.1 COG1007 NADH:ubiquinone oxidoreductase subunit 2 (chain N); NADH dehydrogenase I subunit N 948527 17441502 AFR_04275 Actinoplanes friuliensis DSM 7358 NADH dehydrogenase I subunit N YP_008732197.1 947061 D 1246995 CDS YP_008732198.1 556563773 17441503 949047..949970 1 NC_022657.1 COG0501 Zn-dependent protease with chaperone function; putative M48-family peptidase 949970 17441503 AFR_04280 Actinoplanes friuliensis DSM 7358 putative M48-family peptidase YP_008732198.1 949047 D 1246995 CDS YP_008732199.1 556563774 17441504 950101..951363 1 NC_022657.1 COG0477 Permeases of the major facilitator superfamily; putative MFS transporter 951363 17441504 AFR_04285 Actinoplanes friuliensis DSM 7358 putative MFS transporter YP_008732199.1 950101 D 1246995 CDS YP_008732200.1 556563775 17441505 951435..952844 1 NC_022657.1 COG0477 Permeases of the major facilitator superfamily; putative MFS transporter 952844 17441505 AFR_04290 Actinoplanes friuliensis DSM 7358 putative MFS transporter YP_008732200.1 951435 D 1246995 CDS YP_008732201.1 556563776 17441506 complement(952686..953387) 1 NC_022657.1 COG2188 Transcriptional regulators; GntR family transcriptional regulator 953387 17441506 AFR_04295 Actinoplanes friuliensis DSM 7358 GntR family transcriptional regulator YP_008732201.1 952686 R 1246995 CDS YP_008732202.1 556563777 17441507 953558..954925 1 NC_022657.1 hydrolase 954925 17441507 AFR_04300 Actinoplanes friuliensis DSM 7358 hydrolase YP_008732202.1 953558 D 1246995 CDS YP_008732203.1 556563778 17441508 complement(954976..956253) 1 NC_022657.1 COG0739 Membrane proteins related to metalloendopeptidases; Esterase 956253 17441508 AFR_04305 Actinoplanes friuliensis DSM 7358 Esterase YP_008732203.1 954976 R 1246995 CDS YP_008732204.1 556563779 17441509 956602..957132 1 NC_022657.1 COG1309 Transcriptional regulator; transcriptional regulator 957132 17441509 AFR_04310 Actinoplanes friuliensis DSM 7358 transcriptional regulator YP_008732204.1 956602 D 1246995 CDS YP_008732205.1 556563780 17441510 957150..958145 1 NC_022657.1 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases; putative luciferase-like monooxygenase 958145 17441510 AFR_04315 Actinoplanes friuliensis DSM 7358 putative luciferase-like monooxygenase YP_008732205.1 957150 D 1246995 CDS YP_008732206.1 556563781 17441511 958182..959006 1 NC_022657.1 COG3393 Predicted acetyltransferase; N-acetyltransferase 959006 17441511 AFR_04320 Actinoplanes friuliensis DSM 7358 N-acetyltransferase YP_008732206.1 958182 D 1246995 CDS YP_008732207.1 556563782 17441512 959003..959662 1 NC_022657.1 COG2258 Uncharacterized protein conserved in bacteria; MOSC domain-containing protein 959662 17441512 AFR_04325 Actinoplanes friuliensis DSM 7358 MOSC domain-containing protein YP_008732207.1 959003 D 1246995 CDS YP_008732208.1 556563783 17441513 959730..960983 1 NC_022657.1 COG5659 FOG: Transposase; putative transposase 960983 17441513 AFR_04330 Actinoplanes friuliensis DSM 7358 putative transposase YP_008732208.1 959730 D 1246995 CDS YP_008732209.1 556563784 17441514 complement(961274..961567) 1 NC_022657.1 hypothetical protein 961567 17441514 AFR_04335 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732209.1 961274 R 1246995 CDS YP_008732210.1 556563785 17441515 961861..963057 1 NC_022657.1 COG4941 Predicted RNA polymerase sigma factor containing a TPR repeat domain; RNA polymerase, sigma-24 subunit, ecf subfamily protein 963057 17441515 AFR_04340 Actinoplanes friuliensis DSM 7358 RNA polymerase, sigma-24 subunit, ecf subfamily protein YP_008732210.1 961861 D 1246995 CDS YP_008732211.1 556563786 17441516 complement(963054..963404) 1 NC_022657.1 COG3795 Uncharacterized protein conserved in bacteria; hypothetical protein 963404 17441516 AFR_04345 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732211.1 963054 R 1246995 CDS YP_008732212.1 556563787 17441517 963529..964614 1 NC_022657.1 hypothetical protein 964614 17441517 AFR_04350 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732212.1 963529 D 1246995 CDS YP_008732213.1 556563788 17441518 complement(964608..965753) 1 NC_022657.1 hypothetical protein 965753 17441518 AFR_04355 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732213.1 964608 R 1246995 CDS YP_008732214.1 556563789 17441519 966252..966830 1 NC_022657.1 COG0262 Dihydrofolate reductase; deaminase-reductase domain-containing protein 966830 17441519 AFR_04360 Actinoplanes friuliensis DSM 7358 deaminase-reductase domain-containing protein YP_008732214.1 966252 D 1246995 CDS YP_008732215.1 556563790 17441520 complement(966820..967512) 1 NC_022657.1 AraC family transcriptional regulator 967512 17441520 AFR_04365 Actinoplanes friuliensis DSM 7358 AraC family transcriptional regulator YP_008732215.1 966820 R 1246995 CDS YP_008732216.1 556563791 17441521 967583..968206 1 NC_022657.1 hypothetical protein 968206 17441521 AFR_04370 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732216.1 967583 D 1246995 CDS YP_008732217.1 556563792 17441522 complement(968220..969191) 1 NC_022657.1 COG0657 Esterase/lipase; heroin esterase 969191 17441522 AFR_04375 Actinoplanes friuliensis DSM 7358 heroin esterase YP_008732217.1 968220 R 1246995 CDS YP_008732218.1 556563793 17441524 969586..970080 1 NC_022657.1 COG1666 Uncharacterized protein conserved in bacteria; nucleotide-binding protein 970080 17441524 AFR_04380 Actinoplanes friuliensis DSM 7358 nucleotide-binding protein YP_008732218.1 969586 D 1246995 CDS YP_008732219.1 556563794 17441525 970111..970410 1 NC_022657.1 hypothetical protein 970410 17441525 AFR_04385 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732219.1 970111 D 1246995 CDS YP_008732220.1 556563795 17441526 970424..971233 1 NC_022657.1 COG2897 Rhodanese-related sulfurtransferase; putative thiosulfate sulfurtransferase 971233 17441526 AFR_04390 Actinoplanes friuliensis DSM 7358 putative thiosulfate sulfurtransferase YP_008732220.1 970424 D 1246995 CDS YP_008732221.1 556563796 17441527 complement(971230..971553) 1 NC_022657.1 hypothetical protein 971553 17441527 AFR_04395 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732221.1 971230 R 1246995 CDS YP_008732222.1 556563797 17441528 972197..974653 1 NC_022657.1 COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain; putative cGMP-specific phosphodiesterase 974653 17441528 AFR_04400 Actinoplanes friuliensis DSM 7358 putative cGMP-specific phosphodiesterase YP_008732222.1 972197 D 1246995 CDS YP_008732223.1 556563798 17441531 975061..975228 1 NC_022657.1 COG0267 Ribosomal protein L33; 50S ribosomal protein L33 975228 17441531 AFR_04405 Actinoplanes friuliensis DSM 7358 50S ribosomal protein L33 YP_008732223.1 975061 D 1246995 CDS YP_008732224.1 556563799 17441532 975316..975762 1 NC_022657.1 hypothetical protein 975762 17441532 AFR_04410 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732224.1 975316 D 1246995 CDS YP_008732225.1 556563800 17441533 975765..976160 1 NC_022657.1 COG2030 Acyl dehydratase; dehydratase 976160 17441533 AFR_04415 Actinoplanes friuliensis DSM 7358 dehydratase YP_008732225.1 975765 D 1246995 CDS YP_008732226.1 556563801 17441535 976457..976834 1 NC_022657.1 COG0690 Preprotein translocase subunit SecE; preprotein translocase subunit SecE 976834 17441535 AFR_04420 Actinoplanes friuliensis DSM 7358 preprotein translocase subunit SecE YP_008732226.1 976457 D 1246995 CDS YP_008732227.1 556563802 17441536 976862..977614 1 NC_022657.1 COG0250 Transcription antiterminator; putative transcription antitermination protein 977614 17441536 AFR_04425 Actinoplanes friuliensis DSM 7358 putative transcription antitermination protein YP_008732227.1 976862 D 1246995 CDS YP_008732228.1 556563803 17441537 977683..978402 1 NC_022657.1 COG0081 Ribosomal protein L1; 50S ribosomal protein L1 978402 rplA 17441537 rplA Actinoplanes friuliensis DSM 7358 50S ribosomal protein L1 YP_008732228.1 977683 D 1246995 CDS YP_008732229.1 556563804 17441538 978474..979208 1 NC_022657.1 COG1121 ABC-type Mn/Zn transport systems, ATPase component; putative ABC transporter ATP-binding protein 979208 17441538 AFR_04435 Actinoplanes friuliensis DSM 7358 putative ABC transporter ATP-binding protein YP_008732229.1 978474 D 1246995 CDS YP_008732230.1 556563805 17441539 979205..979900 1 NC_022657.1 hypothetical protein 979900 17441539 AFR_04440 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732230.1 979205 D 1246995 CDS YP_008732231.1 556563806 17441540 980158..980703 1 NC_022657.1 COG0244 Ribosomal protein L10; 50S ribosomal protein L10 980703 rplJ 17441540 rplJ Actinoplanes friuliensis DSM 7358 50S ribosomal protein L10 YP_008732231.1 980158 D 1246995 CDS YP_008732232.1 556563807 17441541 complement(980704..981078) 1 NC_022657.1 50S ribosomal protein L7/L12 981078 17441541 AFR_04450 Actinoplanes friuliensis DSM 7358 50S ribosomal protein L7/L12 YP_008732232.1 980704 R 1246995 CDS YP_008732233.1 556563808 17441542 980762..981145 1 NC_022657.1 COG0222 Ribosomal protein L7/L12; 50S ribosomal protein L7/L12 981145 17441542 AFR_04455 Actinoplanes friuliensis DSM 7358 50S ribosomal protein L7/L12 YP_008732233.1 980762 D 1246995 CDS YP_008732234.1 556563809 17441543 981756..985196 1 NC_022657.1 COG0085 DNA-directed RNA polymerase, beta subunit/140 kD subunit; DNA-directed RNA polymerase subunit beta 985196 rpoB 17441543 rpoB Actinoplanes friuliensis DSM 7358 DNA-directed RNA polymerase subunit beta YP_008732234.1 981756 D 1246995 CDS YP_008732235.1 556563810 17441544 985287..989177 1 NC_022657.1 COG0086 DNA-directed RNA polymerase, beta' subunit/160 kD subunit; DNA-directed RNA polymerase subunit beta' 989177 17441544 AFR_04465 Actinoplanes friuliensis DSM 7358 DNA-directed RNA polymerase subunit beta' YP_008732235.1 985287 D 1246995 CDS YP_008732236.1 556563811 17441545 989254..989607 1 NC_022657.1 hypothetical protein 989607 17441545 AFR_04470 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732236.1 989254 D 1246995 CDS YP_008732237.1 556563812 17441546 989777..990199 1 NC_022657.1 hypothetical protein 990199 17441546 AFR_04475 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732237.1 989777 D 1246995 CDS YP_008732238.1 556563813 17441547 990590..990964 1 NC_022657.1 COG0048 Ribosomal protein S12; 30S ribosomal protein S12 990964 rpsL 17441547 rpsL Actinoplanes friuliensis DSM 7358 30S ribosomal protein S12 YP_008732238.1 990590 D 1246995 CDS YP_008732239.1 556563814 17441548 990966..991436 1 NC_022657.1 COG0049 Ribosomal protein S7; 30S ribosomal protein S7 991436 17441548 AFR_04485 Actinoplanes friuliensis DSM 7358 30S ribosomal protein S7 YP_008732239.1 990966 D 1246995 CDS YP_008732240.1 556563815 17441549 991527..993623 1 NC_022657.1 COG0480 Translation elongation factors (GTPases); elongation factor G 993623 17441549 AFR_04490 Actinoplanes friuliensis DSM 7358 elongation factor G YP_008732240.1 991527 D 1246995 CDS YP_008732241.1 556563816 17441550 993745..994938 1 NC_022657.1 COG0050 GTPases - translation elongation factors; elongation factor Tu 994938 17441550 AFR_04495 Actinoplanes friuliensis DSM 7358 elongation factor Tu YP_008732241.1 993745 D 1246995 CDS YP_008732242.1 556563817 17441551 995312..995620 1 NC_022657.1 COG0051 Ribosomal protein S10; 30S ribosomal protein S10 995620 rpsJ 17441551 rpsJ Actinoplanes friuliensis DSM 7358 30S ribosomal protein S10 YP_008732242.1 995312 D 1246995 CDS YP_008732243.1 556563818 17441552 995644..996285 1 NC_022657.1 COG0087 Ribosomal protein L3; 50S ribosomal protein L3 996285 rplC 17441552 rplC Actinoplanes friuliensis DSM 7358 50S ribosomal protein L3 YP_008732243.1 995644 D 1246995 CDS YP_008732244.1 556563819 17441553 996282..996932 1 NC_022657.1 COG0088 Ribosomal protein L4; 50S ribosomal protein L4 996932 rplD 17441553 rplD Actinoplanes friuliensis DSM 7358 50S ribosomal protein L4 YP_008732244.1 996282 D 1246995 CDS YP_008732245.1 556563820 17441554 996929..997231 1 NC_022657.1 COG0089 Ribosomal protein L23; 50S ribosomal protein L23 997231 rplW 17441554 rplW Actinoplanes friuliensis DSM 7358 50S ribosomal protein L23 YP_008732245.1 996929 D 1246995 CDS YP_008732246.1 556563821 17441555 997245..998084 1 NC_022657.1 COG0090 Ribosomal protein L2; 50S ribosomal protein L2 998084 rplB 17441555 rplB Actinoplanes friuliensis DSM 7358 50S ribosomal protein L2 YP_008732246.1 997245 D 1246995 CDS YP_008732247.1 556563822 17441556 998098..998379 1 NC_022657.1 COG0185 Ribosomal protein S19; 30S ribosomal protein S19 998379 rpsS 17441556 rpsS Actinoplanes friuliensis DSM 7358 30S ribosomal protein S19 YP_008732247.1 998098 D 1246995 CDS YP_008732248.1 556563823 17441557 998416..998877 1 NC_022657.1 COG0091 Ribosomal protein L22; 50S ribosomal protein L22 998877 rplV 17441557 rplV Actinoplanes friuliensis DSM 7358 50S ribosomal protein L22 YP_008732248.1 998416 D 1246995 CDS YP_008732249.1 556563824 17441558 998877..999752 1 NC_022657.1 COG0092 Ribosomal protein S3; 30S ribosomal protein S3 999752 rpsC 17441558 rpsC Actinoplanes friuliensis DSM 7358 30S ribosomal protein S3 YP_008732249.1 998877 D 1246995 CDS YP_008732250.1 556563825 17441559 999736..1000161 1 NC_022657.1 COG0197 Ribosomal protein L16/L10E; 50S ribosomal protein L16 1000161 rplP 17441559 rplP Actinoplanes friuliensis DSM 7358 50S ribosomal protein L16 YP_008732250.1 999736 D 1246995 CDS YP_008732251.1 556563826 17441560 1000161..1000397 1 NC_022657.1 COG0255 Ribosomal protein L29; 50S ribosomal protein L29 1000397 17441560 AFR_04545 Actinoplanes friuliensis DSM 7358 50S ribosomal protein L29 YP_008732251.1 1000161 D 1246995 CDS YP_008732252.1 556563827 17441561 1000394..1000669 1 NC_022657.1 COG0186 Ribosomal protein S17; 30S ribosomal protein S17 1000669 17441561 AFR_04550 Actinoplanes friuliensis DSM 7358 30S ribosomal protein S17 YP_008732252.1 1000394 D 1246995 CDS YP_008732253.1 556563828 17441562 1000770..1001138 1 NC_022657.1 COG0093 Ribosomal protein L14; 50S ribosomal protein L14 1001138 rplN 17441562 rplN Actinoplanes friuliensis DSM 7358 50S ribosomal protein L14 YP_008732253.1 1000770 D 1246995 CDS YP_008732254.1 556563829 17441563 1001141..1001455 1 NC_022657.1 COG0198 Ribosomal protein L24; 50S ribosomal protein L24 1001455 rplX 17441563 rplX Actinoplanes friuliensis DSM 7358 50S ribosomal protein L24 YP_008732254.1 1001141 D 1246995 CDS YP_008732255.1 556563830 17441564 1001455..1002024 1 NC_022657.1 COG0094 Ribosomal protein L5; 50S ribosomal protein L5 1002024 17441564 AFR_04565 Actinoplanes friuliensis DSM 7358 50S ribosomal protein L5 YP_008732255.1 1001455 D 1246995 CDS YP_008732256.1 556563831 17441565 1002027..1002212 1 NC_022657.1 COG0199 Ribosomal protein S14; 30S ribosomal protein S14 1002212 rpsN 17441565 rpsN Actinoplanes friuliensis DSM 7358 30S ribosomal protein S14 YP_008732256.1 1002027 D 1246995 CDS YP_008732257.1 556563832 17441566 1002288..1002695 1 NC_022657.1 COG0096 Ribosomal protein S8; 30S ribosomal protein S8 1002695 rpsH 17441566 rpsH Actinoplanes friuliensis DSM 7358 30S ribosomal protein S8 YP_008732257.1 1002288 D 1246995 CDS YP_008732258.1 556563833 17441567 1002709..1003251 1 NC_022657.1 COG0097 Ribosomal protein L6P/L9E; 50S ribosomal protein L6 1003251 rplF 17441567 rplF Actinoplanes friuliensis DSM 7358 50S ribosomal protein L6 YP_008732258.1 1002709 D 1246995 CDS YP_008732259.1 556563834 17441568 1003248..1003643 1 NC_022657.1 COG0256 Ribosomal protein L18; 50S ribosomal protein L18 1003643 rplR 17441568 rplR Actinoplanes friuliensis DSM 7358 50S ribosomal protein L18 YP_008732259.1 1003248 D 1246995 CDS YP_008732260.1 556563835 17441569 1003656..1004276 1 NC_022657.1 COG0098 Ribosomal protein S5; 30S ribosomal protein S5 1004276 rpsE 17441569 rpsE Actinoplanes friuliensis DSM 7358 30S ribosomal protein S5 YP_008732260.1 1003656 D 1246995 CDS YP_008732261.1 556563836 17441570 1004276..1004458 1 NC_022657.1 COG1841 Ribosomal protein L30/L7E; 50S ribosomal protein L30 1004458 rpmD 17441570 rpmD Actinoplanes friuliensis DSM 7358 50S ribosomal protein L30 YP_008732261.1 1004276 D 1246995 CDS YP_008732262.1 556563837 17441571 1004458..1004901 1 NC_022657.1 COG0200 Ribosomal protein L15; 50S ribosomal protein L15 1004901 17441571 AFR_04600 Actinoplanes friuliensis DSM 7358 50S ribosomal protein L15 YP_008732262.1 1004458 D 1246995 CDS YP_008732263.1 556563838 17441572 1005177..1006523 1 NC_022657.1 COG0201 Preprotein translocase subunit SecY; preprotein translocase subunit SecY 1006523 secY 17441572 secY Actinoplanes friuliensis DSM 7358 preprotein translocase subunit SecY YP_008732263.1 1005177 D 1246995 CDS YP_008732264.1 556563839 17441573 1006598..1007251 1 NC_022657.1 COG0563 Adenylate kinase and related kinases; adenylate kinase 1007251 adk 17441573 adk Actinoplanes friuliensis DSM 7358 adenylate kinase YP_008732264.1 1006598 D 1246995 CDS YP_008732265.1 556563840 17441574 1007253..1008107 1 NC_022657.1 COG0024 Methionine aminopeptidase; methionyl aminopeptidase 1008107 17441574 AFR_04615 Actinoplanes friuliensis DSM 7358 methionyl aminopeptidase YP_008732265.1 1007253 D 1246995 CDS YP_008732266.1 556563841 17441575 1008117..1008554 1 NC_022657.1 COG1253 Hemolysins and related proteins containing CBS domains; hypothetical protein 1008554 17441575 AFR_04620 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732266.1 1008117 D 1246995 CDS YP_008732267.1 556563842 17441576 1008579..1009118 1 NC_022657.1 hypothetical protein 1009118 17441576 AFR_04625 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732267.1 1008579 D 1246995 CDS YP_008732268.1 556563843 17441577 1009359..1009580 1 NC_022657.1 COG0361 Translation initiation factor 1 (IF-1); translation initiation factor IF-1 1009580 17441577 AFR_04630 Actinoplanes friuliensis DSM 7358 translation initiation factor IF-1 YP_008732268.1 1009359 D 1246995 CDS YP_008732269.1 556563844 17441578 1009632..1009745 1 NC_022657.1 COG0257 Ribosomal protein L36; 50S ribosomal protein L36 1009745 rpmJ 17441578 rpmJ Actinoplanes friuliensis DSM 7358 50S ribosomal protein L36 YP_008732269.1 1009632 D 1246995 CDS YP_008732270.1 556563845 17441579 1009918..1010298 1 NC_022657.1 COG0099 Ribosomal protein S13; 30S ribosomal protein S13 1010298 rpsM 17441579 rpsM Actinoplanes friuliensis DSM 7358 30S ribosomal protein S13 YP_008732270.1 1009918 D 1246995 CDS YP_008732271.1 556563846 17441580 1010316..1010723 1 NC_022657.1 COG0100 Ribosomal protein S11; 30S ribosomal protein S11 1010723 17441580 AFR_04645 Actinoplanes friuliensis DSM 7358 30S ribosomal protein S11 YP_008732271.1 1010316 D 1246995 CDS YP_008732272.1 556563847 17441581 1010740..1011366 1 NC_022657.1 COG0522 Ribosomal protein S4 and related proteins; 30S ribosomal protein S4 1011366 rpsD 17441581 rpsD Actinoplanes friuliensis DSM 7358 30S ribosomal protein S4 YP_008732272.1 1010740 D 1246995 CDS YP_008732273.1 556563848 17441582 1011463..1012485 1 NC_022657.1 COG0202 DNA-directed RNA polymerase, alpha subunit/40 kD subunit; DNA-directed RNA polymerase subunit alpha 1012485 17441582 AFR_04655 Actinoplanes friuliensis DSM 7358 DNA-directed RNA polymerase subunit alpha YP_008732273.1 1011463 D 1246995 CDS YP_008732274.1 556563849 17441583 1012519..1013103 1 NC_022657.1 COG0203 Ribosomal protein L17; 50S ribosomal protein L17 1013103 rplQ 17441583 rplQ Actinoplanes friuliensis DSM 7358 50S ribosomal protein L17 YP_008732274.1 1012519 D 1246995 CDS YP_008732275.1 556563850 17441584 1013186..1014001 1 NC_022657.1 COG0101 Pseudouridylate synthase; putative tRNA pseudouridine synthase 1014001 17441584 AFR_04665 Actinoplanes friuliensis DSM 7358 putative tRNA pseudouridine synthase YP_008732275.1 1013186 D 1246995 CDS YP_008732276.1 556563851 17441585 complement(1014059..1014715) 1 NC_022657.1 hypothetical protein 1014715 17441585 AFR_04670 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732276.1 1014059 R 1246995 CDS YP_008732277.1 556563852 17441586 1015137..1015751 1 NC_022657.1 COG2813 16S RNA G1207 methylase RsmC; putative ribosomal RNA small subunit methyltransferase 1015751 17441586 AFR_04675 Actinoplanes friuliensis DSM 7358 putative ribosomal RNA small subunit methyltransferase YP_008732277.1 1015137 D 1246995 CDS YP_008732278.1 556563853 17441587 1015783..1017438 1 NC_022657.1 COG0488 ATPase components of ABC transporters with duplicated ATPase domains; putative ABC transporter ATP-binding protein 1017438 17441587 AFR_04680 Actinoplanes friuliensis DSM 7358 putative ABC transporter ATP-binding protein YP_008732278.1 1015783 D 1246995 CDS YP_008732279.1 556563854 17441588 complement(1017435..1017809) 1 NC_022657.1 hypothetical protein 1017809 17441588 AFR_04685 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732279.1 1017435 R 1246995 CDS YP_008732280.1 556563855 17441589 1018042..1018677 1 NC_022657.1 COG0352 Thiamine monophosphate synthase; thiamine-phosphate pyrophosphorylase 1018677 17441589 AFR_04690 Actinoplanes friuliensis DSM 7358 thiamine-phosphate pyrophosphorylase YP_008732280.1 1018042 D 1246995 CDS YP_008732281.1 556563856 17441590 1018674..1019708 1 NC_022657.1 COG0665 Glycine/D-amino acid oxidases (deaminating); putative glycine oxidase 1019708 17441590 AFR_04695 Actinoplanes friuliensis DSM 7358 putative glycine oxidase YP_008732281.1 1018674 D 1246995 CDS YP_008732282.1 556563857 17441591 1019705..1019902 1 NC_022657.1 COG2104 Sulfur transfer protein involved in thiamine biosynthesis; putative sulfur transfer protein 1019902 17441591 AFR_04700 Actinoplanes friuliensis DSM 7358 putative sulfur transfer protein YP_008732282.1 1019705 D 1246995 CDS YP_008732283.1 556563858 17441592 1019904..1020644 1 NC_022657.1 COG2022 Uncharacterized enzyme of thiazole biosynthesis; thiazole synthase 1020644 thiG 17441592 thiG Actinoplanes friuliensis DSM 7358 thiazole synthase YP_008732283.1 1019904 D 1246995 CDS YP_008732284.1 556563859 17441593 1020638..1021207 1 NC_022657.1 COG0352 Thiamine monophosphate synthase; thiamine-phosphate pyrophosphorylase 1021207 17441593 AFR_04710 Actinoplanes friuliensis DSM 7358 thiamine-phosphate pyrophosphorylase YP_008732284.1 1020638 D 1246995 CDS YP_008732285.1 556563860 17441594 1021204..1021962 1 NC_022657.1 COG0351 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase; hydroxymethylpyrimidine kinase 1021962 17441594 AFR_04715 Actinoplanes friuliensis DSM 7358 hydroxymethylpyrimidine kinase YP_008732285.1 1021204 D 1246995 CDS YP_008732286.1 556563861 17441595 1022047..1023615 1 NC_022657.1 COG0422 Thiamine biosynthesis protein ThiC; phosphomethylpyrimidine synthase ThiC 1023615 17441595 AFR_04720 Actinoplanes friuliensis DSM 7358 phosphomethylpyrimidine synthase ThiC YP_008732286.1 1022047 D 1246995 CDS YP_008732287.1 556563862 17441596 complement(1023624..1025591) 1 NC_022657.1 hypothetical protein 1025591 17441596 AFR_04725 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732287.1 1023624 R 1246995 CDS YP_008732288.1 556563863 17441597 complement(1025666..1025980) 1 NC_022657.1 cupin 2 barrel domain-containing protein 1025980 17441597 AFR_04730 Actinoplanes friuliensis DSM 7358 cupin 2 barrel domain-containing protein YP_008732288.1 1025666 R 1246995 CDS YP_008732289.1 556563864 17441598 complement(1025977..1026906) 1 NC_022657.1 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases; f420-dependent oxidoreductase 1026906 17441598 AFR_04735 Actinoplanes friuliensis DSM 7358 f420-dependent oxidoreductase YP_008732289.1 1025977 R 1246995 CDS YP_008732290.1 556563865 17441599 complement(1026916..1027665) 1 NC_022657.1 COG1116 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component; ABC transporter-like protein 1027665 17441599 AFR_04740 Actinoplanes friuliensis DSM 7358 ABC transporter-like protein YP_008732290.1 1026916 R 1246995 CDS YP_008732291.1 556563866 17441600 1027925..1028932 1 NC_022657.1 COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components; membrane lipoprotein lipid attachment site 1028932 17441600 AFR_04745 Actinoplanes friuliensis DSM 7358 membrane lipoprotein lipid attachment site YP_008732291.1 1027925 D 1246995 CDS YP_008732292.1 556563867 17441601 1029004..1029828 1 NC_022657.1 COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component; binding-protein-dependent transport system inner membrane protein 1029828 17441601 AFR_04750 Actinoplanes friuliensis DSM 7358 binding-protein-dependent transport system inner membrane protein YP_008732292.1 1029004 D 1246995 CDS YP_008732293.1 556563868 17441602 complement(1029890..1031041) 1 NC_022657.1 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component; extracellular ligand-binding receptor 1031041 17441602 AFR_04755 Actinoplanes friuliensis DSM 7358 extracellular ligand-binding receptor YP_008732293.1 1029890 R 1246995 CDS YP_008732294.1 556563869 17441603 1031515..1034766 1 NC_022657.1 COG0642 Signal transduction histidine kinase; histidine kinase 1034766 17441603 AFR_04760 Actinoplanes friuliensis DSM 7358 histidine kinase YP_008732294.1 1031515 D 1246995 CDS YP_008732295.1 556563870 17441604 1034763..1035176 1 NC_022657.1 COG2018 Uncharacterized distant relative of homeotic protein bithoraxoid; hypothetical protein 1035176 17441604 AFR_04765 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732295.1 1034763 D 1246995 CDS YP_008732296.1 556563871 17441605 1035236..1035598 1 NC_022657.1 hypothetical protein 1035598 17441605 AFR_04770 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732296.1 1035236 D 1246995 CDS YP_008732297.1 556563872 17441606 1035579..1036199 1 NC_022657.1 COG2229 Predicted GTPase; putative ATP/GTP-binding protein 1036199 17441606 AFR_04775 Actinoplanes friuliensis DSM 7358 putative ATP/GTP-binding protein YP_008732297.1 1035579 D 1246995 CDS YP_008732298.1 556563873 17441607 complement(1036266..1037414) 1 NC_022657.1 COG1587 Uroporphyrinogen-III synthase; bifunctional uroporphyrinogen-III synthetase/response regulator domain protein 1037414 17441607 AFR_04780 Actinoplanes friuliensis DSM 7358 bifunctional uroporphyrinogen-III synthetase/response regulator domain protein YP_008732298.1 1036266 R 1246995 CDS YP_008732299.1 556563874 17441608 1038201..1038644 1 NC_022657.1 COG0102 Ribosomal protein L13; 50S ribosomal protein L13 1038644 rplM 17441608 rplM Actinoplanes friuliensis DSM 7358 50S ribosomal protein L13 YP_008732299.1 1038201 D 1246995 CDS YP_008732300.1 556563875 17441609 1038665..1039234 1 NC_022657.1 COG0103 Ribosomal protein S9; 30S ribosomal protein S9 1039234 17441609 AFR_04790 Actinoplanes friuliensis DSM 7358 30S ribosomal protein S9 YP_008732300.1 1038665 D 1246995 CDS YP_008732301.1 556563876 17441610 1039390..1040742 1 NC_022657.1 COG1109 Phosphomannomutase; putative phosphoglucomutase/phosphomannomutase 1040742 17441610 AFR_04795 Actinoplanes friuliensis DSM 7358 putative phosphoglucomutase/phosphomannomutase YP_008732301.1 1039390 D 1246995 CDS YP_008732302.1 556563877 17441611 complement(1041018..1042205) 1 NC_022657.1 COG0436 Aspartate/tyrosine/aromatic aminotransferase; aminotransferase 1042205 17441611 AFR_04800 Actinoplanes friuliensis DSM 7358 aminotransferase YP_008732302.1 1041018 R 1246995 CDS YP_008732303.1 556563878 17441612 complement(1042234..1043076) 1 NC_022657.1 hypothetical protein 1043076 17441612 AFR_04805 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732303.1 1042234 R 1246995 CDS YP_008732304.1 556563879 17441613 1043330..1045213 1 NC_022657.1 COG0449 Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains; glucosamine--fructose-6-phosphate aminotransferase 1045213 17441613 AFR_04810 Actinoplanes friuliensis DSM 7358 glucosamine--fructose-6-phosphate aminotransferase YP_008732304.1 1043330 D 1246995 CDS YP_008732305.1 556563880 17441614 complement(1045200..1046603) 1 NC_022657.1 hypothetical protein 1046603 17441614 AFR_04815 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732305.1 1045200 R 1246995 CDS YP_008732306.1 556563881 17441615 complement(1046600..1046878) 1 NC_022657.1 hypothetical protein 1046878 17441615 AFR_04820 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732306.1 1046600 R 1246995 CDS YP_008732307.1 556563882 17441616 1047028..1047396 1 NC_022657.1 COG0736 Phosphopantetheinyl transferase (holo-ACP synthase); holo-(acyl-carrier-protein) synthase 1047396 17441616 AFR_04825 Actinoplanes friuliensis DSM 7358 holo-(acyl-carrier-protein) synthase YP_008732307.1 1047028 D 1246995 CDS YP_008732308.1 556563883 17441617 1047484..1048881 1 NC_022657.1 COG0062 Uncharacterized conserved protein; hypothetical protein 1048881 17441617 AFR_04830 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732308.1 1047484 D 1246995 CDS YP_008732309.1 556563884 17441618 1048912..1050477 1 NC_022657.1 COG0787 Alanine racemase; alanine racemase 1050477 alr 17441618 alr Actinoplanes friuliensis DSM 7358 alanine racemase YP_008732309.1 1048912 D 1246995 CDS YP_008732310.1 556563885 17441619 1050474..1051568 1 NC_022657.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); hypothetical protein 1051568 17441619 AFR_04840 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732310.1 1050474 D 1246995 CDS YP_008732311.1 556563886 17441620 1051565..1052047 1 NC_022657.1 COG0802 Predicted ATPase or kinase; hypothetical protein 1052047 17441620 AFR_04845 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732311.1 1051565 D 1246995 CDS YP_008732312.1 556563887 17441621 1052044..1052721 1 NC_022657.1 COG0692 Uracil DNA glycosylase; uracil-DNA glycosylase 1052721 17441621 AFR_04850 Actinoplanes friuliensis DSM 7358 uracil-DNA glycosylase YP_008732312.1 1052044 D 1246995 CDS YP_008732313.1 556563888 17441622 1053278..1053988 1 NC_022657.1 COG1214 Inactive homolog of metal-dependent proteases, putative molecular chaperone; peptidase M22, glycoprotease 1053988 17441622 AFR_04855 Actinoplanes friuliensis DSM 7358 peptidase M22, glycoprotease YP_008732313.1 1053278 D 1246995 CDS YP_008732314.1 556563889 17441623 1053988..1054416 1 NC_022657.1 COG0456 Acetyltransferases; ribosomal-protein-alanine N-acetyltransferase 1054416 17441623 AFR_04860 Actinoplanes friuliensis DSM 7358 ribosomal-protein-alanine N-acetyltransferase YP_008732314.1 1053988 D 1246995 CDS YP_008732315.1 556563890 17441624 1054409..1055461 1 NC_022657.1 COG0533 Metal-dependent proteases with possible chaperone activity; UGMP family protein 1055461 17441624 AFR_04865 Actinoplanes friuliensis DSM 7358 UGMP family protein YP_008732315.1 1054409 D 1246995 CDS YP_008732316.1 556563891 17441625 1055470..1055724 1 NC_022657.1 hypothetical protein 1055724 17441625 AFR_04870 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732316.1 1055470 D 1246995 CDS YP_008732317.1 556563892 17441626 1055768..1057453 1 NC_022657.1 COG1132 ABC-type multidrug transport system, ATPase and permease components; putative ABC transporter ATPase and permease protein 1057453 17441626 AFR_04875 Actinoplanes friuliensis DSM 7358 putative ABC transporter ATPase and permease protein YP_008732317.1 1055768 D 1246995 CDS YP_008732318.1 556563893 17441627 1057468..1059225 1 NC_022657.1 COG1132 ABC-type multidrug transport system, ATPase and permease components; Lipid A export ATP-binding/permease protein msbA 1059225 17441627 AFR_04880 Actinoplanes friuliensis DSM 7358 Lipid A export ATP-binding/permease protein msbA YP_008732318.1 1057468 D 1246995 CDS YP_008732319.1 556563894 17441628 complement(1059226..1060401) 1 NC_022657.1 COG1940 Transcriptional regulator/sugar kinase; putative sugar kinase 1060401 17441628 AFR_04885 Actinoplanes friuliensis DSM 7358 putative sugar kinase YP_008732319.1 1059226 R 1246995 CDS YP_008732320.1 556563895 17441629 complement(1060412..1061668) 1 NC_022657.1 COG4214 ABC-type xylose transport system, permease component; ABC transporter permease 1061668 17441629 AFR_04890 Actinoplanes friuliensis DSM 7358 ABC transporter permease YP_008732320.1 1060412 R 1246995 CDS YP_008732321.1 556563896 17441630 complement(1061665..1062480) 1 NC_022657.1 COG1129 ABC-type sugar transport system, ATPase component; putative ABC transporter ATP-binding protein 1062480 17441630 AFR_04895 Actinoplanes friuliensis DSM 7358 putative ABC transporter ATP-binding protein YP_008732321.1 1061665 R 1246995 CDS YP_008732322.1 556563897 17441631 complement(1062559..1063644) 1 NC_022657.1 COG4213 ABC-type xylose transport system, periplasmic component; putative ABC transporter substrate-binding protein 1063644 17441631 AFR_04900 Actinoplanes friuliensis DSM 7358 putative ABC transporter substrate-binding protein YP_008732322.1 1062559 R 1246995 CDS YP_008732323.1 556563898 17441632 complement(1063932..1064420) 1 NC_022657.1 COG2606 Uncharacterized conserved protein; hypothetical protein 1064420 17441632 AFR_04905 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732323.1 1063932 R 1246995 CDS YP_008732324.1 556563899 17441633 complement(1064426..1065592) 1 NC_022657.1 COG0500 SAM-dependent methyltransferases; hypothetical protein 1065592 17441633 AFR_04910 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732324.1 1064426 R 1246995 CDS YP_008732325.1 556563900 17441634 1065831..1066139 1 NC_022657.1 COG0234 Co-chaperonin GroES (HSP10); chaperonin Cpn10 1066139 17441634 AFR_04915 Actinoplanes friuliensis DSM 7358 chaperonin Cpn10 YP_008732325.1 1065831 D 1246995 CDS YP_008732326.1 556563901 17441635 1066213..1067859 1 NC_022657.1 COG0459 Chaperonin GroEL (HSP60 family); 60 kDa chaperonin 1067859 17441635 AFR_04920 Actinoplanes friuliensis DSM 7358 60 kDa chaperonin YP_008732326.1 1066213 D 1246995 CDS YP_008732327.1 556563902 17441636 1067944..1068564 1 NC_022657.1 hypothetical protein 1068564 17441636 AFR_04925 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732327.1 1067944 D 1246995 CDS YP_008732328.1 556563903 17441637 1068600..1070168 1 NC_022657.1 COG2041 Sulfite oxidase and related enzymes; putative molybdopterin oxidoreductase 1070168 17441637 AFR_04930 Actinoplanes friuliensis DSM 7358 putative molybdopterin oxidoreductase YP_008732328.1 1068600 D 1246995 CDS YP_008732329.1 556563904 17441638 complement(1070338..1070727) 1 NC_022657.1 COG0301 Thiamine biosynthesis ATP pyrophosphatase; transcription factor WhiB 1070727 17441638 AFR_04935 Actinoplanes friuliensis DSM 7358 transcription factor WhiB YP_008732329.1 1070338 R 1246995 CDS YP_008732330.1 556563905 17441639 1071045..1071800 1 NC_022657.1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; yxjL-like transcriptional regulatory protein 1071800 17441639 AFR_04940 Actinoplanes friuliensis DSM 7358 yxjL-like transcriptional regulatory protein YP_008732330.1 1071045 D 1246995 CDS YP_008732331.1 556563906 17441640 complement(1072342..1072761) 1 NC_022657.1 hypothetical protein 1072761 17441640 AFR_04945 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732331.1 1072342 R 1246995 CDS YP_008732332.1 556563907 17441641 1072864..1074351 1 NC_022657.1 COG0516 IMP dehydrogenase/GMP reductase; putative inosine-5'-monophosphate dehydrogenase 1074351 17441641 AFR_04950 Actinoplanes friuliensis DSM 7358 putative inosine-5'-monophosphate dehydrogenase YP_008732332.1 1072864 D 1246995 CDS YP_008732333.1 556563908 17441642 1074372..1075490 1 NC_022657.1 COG0516 IMP dehydrogenase/GMP reductase; IMP dehydrogenase 1075490 17441642 AFR_04955 Actinoplanes friuliensis DSM 7358 IMP dehydrogenase YP_008732333.1 1074372 D 1246995 CDS YP_008732334.1 556563909 17441643 1075867..1077084 1 NC_022657.1 COG0308 Aminopeptidase N; putative metallopeptidase 1077084 17441643 AFR_04960 Actinoplanes friuliensis DSM 7358 putative metallopeptidase YP_008732334.1 1075867 D 1246995 CDS YP_008732335.1 556563910 17441644 complement(1077074..1078168) 1 NC_022657.1 COG1316 Transcriptional regulator; putative cell envelope-related transcriptional attenuator 1078168 17441644 AFR_04965 Actinoplanes friuliensis DSM 7358 putative cell envelope-related transcriptional attenuator YP_008732335.1 1077074 R 1246995 CDS YP_008732336.1 556563911 17441645 1078317..1080095 1 NC_022657.1 COG1404 Subtilisin-like serine proteases; putative subtilase-family protease 1080095 17441645 AFR_04970 Actinoplanes friuliensis DSM 7358 putative subtilase-family protease YP_008732336.1 1078317 D 1246995 CDS YP_008732337.1 556563912 17441646 1080164..1081903 1 NC_022657.1 COG1404 Subtilisin-like serine proteases; putative subtilase-family protease 1081903 17441646 AFR_04975 Actinoplanes friuliensis DSM 7358 putative subtilase-family protease YP_008732337.1 1080164 D 1246995 CDS YP_008732338.1 556563913 17441647 1081924..1083477 1 NC_022657.1 COG0518 GMP synthase - Glutamine amidotransferase domain; GMP synthase 1083477 guaA 17441647 guaA Actinoplanes friuliensis DSM 7358 GMP synthase YP_008732338.1 1081924 D 1246995 CDS YP_008732339.1 556563914 17441648 complement(1083482..1083763) 1 NC_022657.1 COG1983 Putative stress-responsive transcriptional regulator; phage shock protein C, PspC 1083763 17441648 AFR_04985 Actinoplanes friuliensis DSM 7358 phage shock protein C, PspC YP_008732339.1 1083482 R 1246995 CDS YP_008732340.1 556563915 17441649 1083993..1084940 1 NC_022657.1 COG1051 ADP-ribose pyrophosphatase; Nudix hydrolase 6 1084940 17441649 AFR_04990 Actinoplanes friuliensis DSM 7358 Nudix hydrolase 6 YP_008732340.1 1083993 D 1246995 CDS YP_008732341.1 556563916 17441650 1084946..1085851 1 NC_022657.1 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; putative NUDIX hydrolase 1085851 17441650 AFR_04995 Actinoplanes friuliensis DSM 7358 putative NUDIX hydrolase YP_008732341.1 1084946 D 1246995 CDS YP_008732342.1 556563917 17441651 1086226..1087101 1 NC_022657.1 COG1183 Phosphatidylserine synthase; putative phosphatidylserine synthase 1087101 17441651 AFR_05000 Actinoplanes friuliensis DSM 7358 putative phosphatidylserine synthase YP_008732342.1 1086226 D 1246995 CDS YP_008732343.1 556563918 17441652 complement(1087400..1088647) 1 NC_022657.1 COG0688 Phosphatidylserine decarboxylase; putative phosphatidylserine decarboxylase 1088647 17441652 AFR_05005 Actinoplanes friuliensis DSM 7358 putative phosphatidylserine decarboxylase YP_008732343.1 1087400 R 1246995 CDS YP_008732344.1 556563919 17441653 complement(1088742..1089143) 1 NC_022657.1 hypothetical protein 1089143 17441653 AFR_05010 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732344.1 1088742 R 1246995 CDS YP_008732345.1 556563920 17441654 complement(1089140..1090750) 1 NC_022657.1 COG1983 Putative stress-responsive transcriptional regulator; Protein piccolo 1090750 17441654 AFR_05015 Actinoplanes friuliensis DSM 7358 Protein piccolo YP_008732345.1 1089140 R 1246995 CDS YP_008732346.1 556563921 17441655 1091027..1092187 1 NC_022657.1 COG4585 Signal transduction histidine kinase; putative sensor-like histidine kinase 1092187 17441655 AFR_05020 Actinoplanes friuliensis DSM 7358 putative sensor-like histidine kinase YP_008732346.1 1091027 D 1246995 CDS YP_008732347.1 556563922 17441656 1092184..1092849 1 NC_022657.1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; putative two-component system response regulator 1092849 17441656 AFR_05025 Actinoplanes friuliensis DSM 7358 putative two-component system response regulator YP_008732347.1 1092184 D 1246995 CDS YP_008732348.1 556563923 17441657 1093143..1094753 1 NC_022657.1 COG4166 ABC-type oligopeptide transport system, periplasmic component; putative ABC transporter substrate-binding protein 1094753 17441657 AFR_05030 Actinoplanes friuliensis DSM 7358 putative ABC transporter substrate-binding protein YP_008732348.1 1093143 D 1246995 CDS YP_008732349.1 556563924 17441658 1094887..1095813 1 NC_022657.1 COG0601 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components; ABC transporter permease 1095813 17441658 AFR_05035 Actinoplanes friuliensis DSM 7358 ABC transporter permease YP_008732349.1 1094887 D 1246995 CDS YP_008732350.1 556563925 17441659 1095806..1096747 1 NC_022657.1 COG1173 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components; ABC transporter permease 1096747 17441659 AFR_05040 Actinoplanes friuliensis DSM 7358 ABC transporter permease YP_008732350.1 1095806 D 1246995 CDS YP_008732351.1 556563926 17441660 1096755..1097786 1 NC_022657.1 COG0444 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component; Dipeptide transport ATP-binding protein dppD 1097786 17441660 AFR_05045 Actinoplanes friuliensis DSM 7358 Dipeptide transport ATP-binding protein dppD YP_008732351.1 1096755 D 1246995 CDS YP_008732352.1 556563927 17441661 1097783..1098799 1 NC_022657.1 COG4608 ABC-type oligopeptide transport system, ATPase component; putative ABC transporter ATP-binding protein 1098799 17441661 AFR_05050 Actinoplanes friuliensis DSM 7358 putative ABC transporter ATP-binding protein YP_008732352.1 1097783 D 1246995 CDS YP_008732353.1 556563928 17441662 complement(1099368..1099739) 1 NC_022657.1 COG0346 Lactoylglutathione lyase and related lyases; glyoxalase/bleomycin resistance protein/dioxygenase 1099739 17441662 AFR_05055 Actinoplanes friuliensis DSM 7358 glyoxalase/bleomycin resistance protein/dioxygenase YP_008732353.1 1099368 R 1246995 CDS YP_008732354.1 556563929 17441663 complement(1100695..1100985) 1 NC_022657.1 COG1605 Chorismate mutase; T-protein 1100985 17441663 AFR_05060 Actinoplanes friuliensis DSM 7358 T-protein YP_008732354.1 1100695 R 1246995 CDS YP_008732355.1 556563930 17441664 complement(1101214..1103064) 1 NC_022657.1 COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; putative 5'-nucleotidase 1103064 17441664 AFR_05065 Actinoplanes friuliensis DSM 7358 putative 5'-nucleotidase YP_008732355.1 1101214 R 1246995 CDS YP_008732356.1 556563931 17441665 1103484..1105796 1 NC_022657.1 COG0210 Superfamily I DNA and RNA helicases; putative ATP-dependent DNA helicase 1105796 17441665 AFR_05070 Actinoplanes friuliensis DSM 7358 putative ATP-dependent DNA helicase YP_008732356.1 1103484 D 1246995 CDS YP_008732357.1 556563932 17441666 complement(1105870..1106715) 1 NC_022657.1 COG0739 Membrane proteins related to metalloendopeptidases; SPBc2 prophage-derived transglycosylase 1106715 17441666 AFR_05075 Actinoplanes friuliensis DSM 7358 SPBc2 prophage-derived transglycosylase YP_008732357.1 1105870 R 1246995 CDS YP_008732358.1 556563933 17441667 complement(1106833..1107444) 1 NC_022657.1 COG0739 Membrane proteins related to metalloendopeptidases; putative M23-family peptidase 1107444 17441667 AFR_05080 Actinoplanes friuliensis DSM 7358 putative M23-family peptidase YP_008732358.1 1106833 R 1246995 CDS YP_008732359.1 556563934 17441668 1107993..1108397 1 NC_022657.1 COG2185 Methylmalonyl-CoA mutase, C-terminal domain/subunit (cobalamin-binding); putative isobutyryl-CoA mutase chain B 1108397 17441668 AFR_05085 Actinoplanes friuliensis DSM 7358 putative isobutyryl-CoA mutase chain B YP_008732359.1 1107993 D 1246995 CDS YP_008732360.1 556563935 17441669 1108814..1109992 1 NC_022657.1 COG0045 Succinyl-CoA synthetase, beta subunit; succinyl-CoA synthetase subunit beta 1109992 sucC 17441669 sucC Actinoplanes friuliensis DSM 7358 succinyl-CoA synthetase subunit beta YP_008732360.1 1108814 D 1246995 CDS YP_008732361.1 556563936 17441670 1109997..1110878 1 NC_022657.1 COG0074 Succinyl-CoA synthetase, alpha subunit; succinyl-CoA synthetase subunit alpha 1110878 17441670 AFR_05095 Actinoplanes friuliensis DSM 7358 succinyl-CoA synthetase subunit alpha YP_008732361.1 1109997 D 1246995 CDS YP_008732362.1 556563937 17441671 1111040..1112491 1 NC_022657.1 hypothetical protein 1112491 17441671 AFR_05100 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732362.1 1111040 D 1246995 CDS YP_008732363.1 556563938 17441672 complement(1113050..1113319) 1 NC_022657.1 hypothetical protein 1113319 17441672 AFR_05105 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732363.1 1113050 R 1246995 CDS YP_008732364.1 556563939 17441673 1113485..1114102 1 NC_022657.1 COG0299 Folate-dependent phosphoribosylglycinamide formyltransferase PurN; phosphoribosylglycinamide formyltransferase 1114102 purN 17441673 purN Actinoplanes friuliensis DSM 7358 phosphoribosylglycinamide formyltransferase YP_008732364.1 1113485 D 1246995 CDS YP_008732365.1 556563940 17441674 1114186..1115697 1 NC_022657.1 COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful); bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 1115697 purH 17441674 purH Actinoplanes friuliensis DSM 7358 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase YP_008732365.1 1114186 D 1246995 CDS YP_008732366.1 556563941 17441675 1115697..1116290 1 NC_022657.1 COG1357 Uncharacterized low-complexity proteins; BTB/POZ domain-containing protein KCTD9 1116290 17441675 AFR_05120 Actinoplanes friuliensis DSM 7358 BTB/POZ domain-containing protein KCTD9 YP_008732366.1 1115697 D 1246995 CDS YP_008732367.1 556563942 17441676 1116391..1117341 1 NC_022657.1 COG0039 Malate/lactate dehydrogenases; lactate/malate dehydrogenase 1117341 17441676 AFR_05125 Actinoplanes friuliensis DSM 7358 lactate/malate dehydrogenase YP_008732367.1 1116391 D 1246995 CDS YP_008732368.1 556563943 17441677 complement(1117385..1118194) 1 NC_022657.1 COG0491 Zn-dependent hydrolases, including glyoxylases; beta-lactamase 1118194 17441677 AFR_05130 Actinoplanes friuliensis DSM 7358 beta-lactamase YP_008732368.1 1117385 R 1246995 CDS YP_008732369.1 556563944 17441678 complement(1118245..1119585) 1 NC_022657.1 COG3540 Phosphodiesterase/alkaline phosphatase D; phosphodiesterase/alkaline phosphatase D 1119585 17441678 AFR_05135 Actinoplanes friuliensis DSM 7358 phosphodiesterase/alkaline phosphatase D YP_008732369.1 1118245 R 1246995 CDS YP_008732370.1 556563945 17441679 1119809..1121023 1 NC_022657.1 COG0538 Isocitrate dehydrogenases; isocitrate dehydrogenase 1121023 17441679 AFR_05140 Actinoplanes friuliensis DSM 7358 isocitrate dehydrogenase YP_008732370.1 1119809 D 1246995 CDS YP_008732371.1 556563946 17441680 complement(1121305..1122396) 1 NC_022657.1 COG1085 Galactose-1-phosphate uridylyltransferase; galactose-1-phosphate uridylyltransferase 1122396 17441680 AFR_05145 Actinoplanes friuliensis DSM 7358 galactose-1-phosphate uridylyltransferase YP_008732371.1 1121305 R 1246995 CDS YP_008732372.1 556563947 17441681 complement(1122393..1123169) 1 NC_022657.1 COG1349 Transcriptional regulators of sugar metabolism; DeoR family transcriptional regulator 1123169 17441681 AFR_05150 Actinoplanes friuliensis DSM 7358 DeoR family transcriptional regulator YP_008732372.1 1122393 R 1246995 CDS YP_008732373.1 556563948 17441682 complement(1123262..1124176) 1 NC_022657.1 COG0463 Glycosyltransferases involved in cell wall biogenesis; Polypeptide N-acetylgalactosaminyltransferase 10 1124176 17441682 AFR_05155 Actinoplanes friuliensis DSM 7358 Polypeptide N-acetylgalactosaminyltransferase 10 YP_008732373.1 1123262 R 1246995 CDS YP_008732374.1 556563949 17441683 complement(1124176..1125078) 1 NC_022657.1 hypothetical protein 1125078 17441683 AFR_05160 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732374.1 1124176 R 1246995 CDS YP_008732375.1 556563950 17441684 1125189..1125974 1 NC_022657.1 COG1922 Teichoic acid biosynthesis proteins; putative glycosyltransferase 1125974 17441684 AFR_05165 Actinoplanes friuliensis DSM 7358 putative glycosyltransferase YP_008732375.1 1125189 D 1246995 CDS YP_008732376.1 556563951 17441685 complement(1125975..1126583) 1 NC_022657.1 hypothetical protein 1126583 17441685 AFR_05170 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732376.1 1125975 R 1246995 CDS YP_008732377.1 556563952 17441686 complement(1126632..1127630) 1 NC_022657.1 COG4124 Beta-mannanase; hypothetical protein 1127630 17441686 AFR_05175 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732377.1 1126632 R 1246995 CDS YP_008732378.1 556563953 17441687 complement(1127639..1128367) 1 NC_022657.1 COG0500 SAM-dependent methyltransferases; hypothetical protein 1128367 17441687 AFR_05180 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732378.1 1127639 R 1246995 CDS YP_008732379.1 556563954 17441688 complement(1128364..1129929) 1 NC_022657.1 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid; hypothetical protein 1129929 17441688 AFR_05185 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732379.1 1128364 R 1246995 CDS YP_008732380.1 556563955 17441689 complement(1129926..1130804) 1 NC_022657.1 putative sulfotransferase 1130804 17441689 AFR_05190 Actinoplanes friuliensis DSM 7358 putative sulfotransferase YP_008732380.1 1129926 R 1246995 CDS YP_008732381.1 556563956 17441690 complement(1130807..1132027) 1 NC_022657.1 hypothetical protein 1132027 17441690 AFR_05195 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732381.1 1130807 R 1246995 CDS YP_008732382.1 556563957 17441691 complement(1132033..1133424) 1 NC_022657.1 hypothetical protein 1133424 17441691 AFR_05200 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732382.1 1132033 R 1246995 CDS YP_008732383.1 556563958 17441692 complement(1133421..1135265) 1 NC_022657.1 COG3944 Capsular polysaccharide biosynthesis protein; hypothetical protein 1135265 17441692 AFR_05205 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732383.1 1133421 R 1246995 CDS YP_008732384.1 556563959 17441693 complement(1135396..1136919) 1 NC_022657.1 COG2046 ATP sulfurylase (sulfate adenylyltransferase); putative adenylylsulfate kinase 1136919 17441693 AFR_05210 Actinoplanes friuliensis DSM 7358 putative adenylylsulfate kinase YP_008732384.1 1135396 R 1246995 CDS YP_008732385.1 556563960 17441694 1137077..1138399 1 NC_022657.1 COG4124 Beta-mannanase; hypothetical protein 1138399 17441694 AFR_05215 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732385.1 1137077 D 1246995 CDS YP_008732386.1 556563961 17441695 1138476..1139390 1 NC_022657.1 COG1131 ABC-type multidrug transport system, ATPase component; spermidine/putrescine import ATP-binding protein potA 1139390 17441695 AFR_05220 Actinoplanes friuliensis DSM 7358 spermidine/putrescine import ATP-binding protein potA YP_008732386.1 1138476 D 1246995 CDS YP_008732387.1 556563962 17441696 1139383..1140246 1 NC_022657.1 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component; hypothetical protein 1140246 17441696 AFR_05225 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732387.1 1139383 D 1246995 CDS YP_008732388.1 556563963 17441697 1140243..1141154 1 NC_022657.1 COG1131 ABC-type multidrug transport system, ATPase component; putative ABC transporter ATP-binding protein 1141154 17441697 AFR_05230 Actinoplanes friuliensis DSM 7358 putative ABC transporter ATP-binding protein YP_008732388.1 1140243 D 1246995 CDS YP_008732389.1 556563964 17441698 1141156..1141866 1 NC_022657.1 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component; hypothetical protein 1141866 17441698 AFR_05235 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732389.1 1141156 D 1246995 CDS YP_008732390.1 556563965 17441699 complement(1142177..1143961) 1 NC_022657.1 COG1106 Predicted ATPases; hypothetical protein 1143961 17441699 AFR_05240 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732390.1 1142177 R 1246995 CDS YP_008732391.1 556563966 17441700 complement(1144052..1144414) 1 NC_022657.1 COG0789 Predicted transcriptional regulators; putative MerR-family transcriptional regulator 1144414 17441700 AFR_05245 Actinoplanes friuliensis DSM 7358 putative MerR-family transcriptional regulator YP_008732391.1 1144052 R 1246995 CDS YP_008732392.1 556563967 17441701 1144489..1145181 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); short-chain dehydrogenase/reductase SDR 1145181 17441701 AFR_05250 Actinoplanes friuliensis DSM 7358 short-chain dehydrogenase/reductase SDR YP_008732392.1 1144489 D 1246995 CDS YP_008732393.1 556563968 17441702 complement(1145238..1148033) 1 NC_022657.1 COG2352 Phosphoenolpyruvate carboxylase; phosphoenolpyruvate carboxylase 1148033 17441702 AFR_05255 Actinoplanes friuliensis DSM 7358 phosphoenolpyruvate carboxylase YP_008732393.1 1145238 R 1246995 CDS YP_008732394.1 556563969 17441703 1148229..1149791 1 NC_022657.1 hypothetical protein 1149791 17441703 AFR_05260 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732394.1 1148229 D 1246995 CDS YP_008732395.1 556563970 17441704 complement(1149832..1151265) 1 NC_022657.1 COG3664 Beta-xylosidase; hypothetical protein 1151265 17441704 AFR_05265 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732395.1 1149832 R 1246995 CDS YP_008732396.1 556563971 17441705 complement(1151323..1152369) 1 NC_022657.1 COG5297 Cellobiohydrolase A (1,4-beta-cellobiosidase A); putative secreted endoglucanase 1152369 17441705 AFR_05270 Actinoplanes friuliensis DSM 7358 putative secreted endoglucanase YP_008732396.1 1151323 R 1246995 CDS YP_008732397.1 556563972 17441706 complement(1152372..1154303) 1 NC_022657.1 hypothetical protein 1154303 17441706 AFR_05275 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732397.1 1152372 R 1246995 CDS YP_008732398.1 556563973 17441707 complement(1154318..1156129) 1 NC_022657.1 COG1215 Glycosyltransferases, probably involved in cell wall biogenesis; putative glycosyltransferase 1156129 17441707 AFR_05280 Actinoplanes friuliensis DSM 7358 putative glycosyltransferase YP_008732398.1 1154318 R 1246995 CDS YP_008732399.1 556563974 17441708 complement(1156203..1157996) 1 NC_022657.1 COG0223 Methionyl-tRNA formyltransferase; putative formyl transferase 1157996 17441708 AFR_05285 Actinoplanes friuliensis DSM 7358 putative formyl transferase YP_008732399.1 1156203 R 1246995 CDS YP_008732400.1 556563975 17441709 1158188..1161799 1 NC_022657.1 COG1197 Transcription-repair coupling factor (superfamily II helicase); transcription-repair coupling factor 1161799 17441709 AFR_05290 Actinoplanes friuliensis DSM 7358 transcription-repair coupling factor YP_008732400.1 1158188 D 1246995 CDS YP_008732401.1 556563976 17441710 1161856..1162623 1 NC_022657.1 hypothetical protein 1162623 17441710 AFR_05295 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732401.1 1161856 D 1246995 CDS YP_008732402.1 556563977 17441711 1162623..1163573 1 NC_022657.1 COG1694 Predicted pyrophosphatase; nucleoside triphosphate pyrophosphohydrolase 1163573 17441711 AFR_05300 Actinoplanes friuliensis DSM 7358 nucleoside triphosphate pyrophosphohydrolase YP_008732402.1 1162623 D 1246995 CDS YP_008732403.1 556563978 17441712 1163597..1165213 1 NC_022657.1 COG4805 Uncharacterized protein conserved in bacteria; hypothetical protein 1165213 17441712 AFR_05305 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732403.1 1163597 D 1246995 CDS YP_008732404.1 556563979 17441713 1165475..1166533 1 NC_022657.1 COG3177 Uncharacterized conserved protein; Fic family protein 1166533 17441713 AFR_05310 Actinoplanes friuliensis DSM 7358 Fic family protein YP_008732404.1 1165475 D 1246995 CDS YP_008732405.1 556563980 17441714 complement(1166530..1167183) 1 NC_022657.1 hypothetical protein 1167183 17441714 AFR_05315 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732405.1 1166530 R 1246995 CDS YP_008732406.1 556563981 17441715 complement(1167264..1167869) 1 NC_022657.1 hypothetical protein 1167869 17441715 AFR_05320 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732406.1 1167264 R 1246995 CDS YP_008732407.1 556563982 17441716 1168051..1169334 1 NC_022657.1 COG0148 Enolase; enolase 1169334 eno 17441716 eno Actinoplanes friuliensis DSM 7358 enolase YP_008732407.1 1168051 D 1246995 CDS YP_008732408.1 556563983 17441717 1169445..1170068 1 NC_022657.1 COG2919 Septum formation initiator; putative septum formation initiator 1170068 17441717 AFR_05330 Actinoplanes friuliensis DSM 7358 putative septum formation initiator YP_008732408.1 1169445 D 1246995 CDS YP_008732409.1 556563984 17441718 1170069..1170569 1 NC_022657.1 COG1507 Uncharacterized conserved protein; hypothetical protein 1170569 17441718 AFR_05335 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732409.1 1170069 D 1246995 CDS YP_008732410.1 556563985 17441719 1170580..1171086 1 NC_022657.1 COG1246 N-acetylglutamate synthase and related acetyltransferases; N-acetylglutamate synthase 1171086 17441719 AFR_05340 Actinoplanes friuliensis DSM 7358 N-acetylglutamate synthase YP_008732410.1 1170580 D 1246995 CDS YP_008732411.1 556563986 17441720 1171096..1172001 1 NC_022657.1 COG0248 Exopolyphosphatase; putative exopolyphosphatase 1172001 17441720 AFR_05345 Actinoplanes friuliensis DSM 7358 putative exopolyphosphatase YP_008732411.1 1171096 D 1246995 CDS YP_008732412.1 556563987 17441721 1172046..1172375 1 NC_022657.1 COG1695 Predicted transcriptional regulators; PadR family transcriptional regulator 1172375 17441721 AFR_05350 Actinoplanes friuliensis DSM 7358 PadR family transcriptional regulator YP_008732412.1 1172046 D 1246995 CDS YP_008732413.1 556563988 17441722 1172372..1173352 1 NC_022657.1 hypothetical protein 1173352 17441722 AFR_05355 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732413.1 1172372 D 1246995 CDS YP_008732414.1 556563989 17441723 1173446..1173997 1 NC_022657.1 Annexin A11 1173997 17441723 AFR_05360 Actinoplanes friuliensis DSM 7358 Annexin A11 YP_008732414.1 1173446 D 1246995 CDS YP_008732415.1 556563990 17441724 1174057..1174806 1 NC_022657.1 COG1573 Uracil-DNA glycosylase; uracil-DNA glycosylase superfamily protein 1174806 17441724 AFR_05365 Actinoplanes friuliensis DSM 7358 uracil-DNA glycosylase superfamily protein YP_008732415.1 1174057 D 1246995 CDS YP_008732416.1 556563991 17441725 1174855..1175550 1 NC_022657.1 hypothetical protein 1175550 17441725 AFR_05370 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732416.1 1174855 D 1246995 CDS YP_008732417.1 556563992 17441726 1175547..1176149 1 NC_022657.1 COG0519 GMP synthase, PP-ATPase domain/subunit; hypothetical protein 1176149 17441726 AFR_05375 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732417.1 1175547 D 1246995 CDS YP_008732418.1 556563993 17441727 1176163..1177173 1 NC_022657.1 COG0714 MoxR-like ATPases; putative ATPase associated with various cellular activities 1177173 17441727 AFR_05380 Actinoplanes friuliensis DSM 7358 putative ATPase associated with various cellular activities YP_008732418.1 1176163 D 1246995 CDS YP_008732419.1 556563994 17441728 1177170..1178540 1 NC_022657.1 COG1721 Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain); hypothetical protein 1178540 17441728 AFR_05385 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732419.1 1177170 D 1246995 CDS YP_008732420.1 556563995 17441729 1178542..1179105 1 NC_022657.1 hypothetical protein 1179105 17441729 AFR_05390 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732420.1 1178542 D 1246995 CDS YP_008732421.1 556563996 17441730 1179435..1180751 1 NC_022657.1 COG1252 NADH dehydrogenase, FAD-containing subunit; putative FAD-dependent pyridine nucleotide-disulfide oxidoreductase 1180751 17441730 AFR_05395 Actinoplanes friuliensis DSM 7358 putative FAD-dependent pyridine nucleotide-disulfide oxidoreductase YP_008732421.1 1179435 D 1246995 CDS YP_008732422.1 556563997 17441732 1181037..1181870 1 NC_022657.1 COG4760 Predicted membrane protein; hypothetical protein 1181870 17441732 AFR_05400 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732422.1 1181037 D 1246995 CDS YP_008732423.1 556563998 17441733 1181952..1182245 1 NC_022657.1 hypothetical protein 1182245 17441733 AFR_05405 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732423.1 1181952 D 1246995 CDS YP_008732424.1 556563999 17441734 complement(1183773..1185014) 1 NC_022657.1 COG0183 Acetyl-CoA acetyltransferase; acetyl-CoA acetyltransferase 1185014 17441734 AFR_05410 Actinoplanes friuliensis DSM 7358 acetyl-CoA acetyltransferase YP_008732424.1 1183773 R 1246995 CDS YP_008732425.1 556564000 17441735 complement(1185069..1185875) 1 NC_022657.1 COG2755 Lysophospholipase L1 and related esterases; putative GDSL-like lipase/acylhydrolase 1185875 17441735 AFR_05415 Actinoplanes friuliensis DSM 7358 putative GDSL-like lipase/acylhydrolase YP_008732425.1 1185069 R 1246995 CDS YP_008732426.1 556564001 17441736 complement(1185904..1186998) 1 NC_022657.1 COG2755 Lysophospholipase L1 and related esterases; putative GDSL-like lipase/acylhydrolase 1186998 17441736 AFR_05420 Actinoplanes friuliensis DSM 7358 putative GDSL-like lipase/acylhydrolase YP_008732426.1 1185904 R 1246995 CDS YP_008732427.1 556564002 17441737 1187195..1187551 1 NC_022657.1 COG3339 Uncharacterized conserved protein; hypothetical protein 1187551 17441737 AFR_05425 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732427.1 1187195 D 1246995 CDS YP_008732428.1 556564003 17441738 1187600..1188958 1 NC_022657.1 COG0031 Cysteine synthase; cystathionine beta-synthase 1188958 17441738 AFR_05430 Actinoplanes friuliensis DSM 7358 cystathionine beta-synthase YP_008732428.1 1187600 D 1246995 CDS YP_008732429.1 556564004 17441739 complement(1189105..1189500) 1 NC_022657.1 hypothetical protein 1189500 17441739 AFR_05435 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732429.1 1189105 R 1246995 CDS YP_008732430.1 556564005 17441740 1189880..1190203 1 NC_022657.1 hypothetical protein 1190203 17441740 AFR_05440 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732430.1 1189880 D 1246995 CDS YP_008732431.1 556564006 17441741 complement(1190159..1191592) 1 NC_022657.1 COG2199 FOG: GGDEF domain; putative signaling protein 1191592 17441741 AFR_05445 Actinoplanes friuliensis DSM 7358 putative signaling protein YP_008732431.1 1190159 R 1246995 CDS YP_008732432.1 556564007 17441742 1192102..1193526 1 NC_022657.1 COG5607 Uncharacterized conserved protein; hypothetical protein 1193526 17441742 AFR_05450 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732432.1 1192102 D 1246995 CDS YP_008732433.1 556564008 17441743 1193602..1194576 1 NC_022657.1 COG2326 Uncharacterized conserved protein; putative polyphosphate kinase 1194576 17441743 AFR_05455 Actinoplanes friuliensis DSM 7358 putative polyphosphate kinase YP_008732433.1 1193602 D 1246995 CDS YP_008732434.1 556564009 17441744 1194849..1195778 1 NC_022657.1 COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III; ribonuclease Z 1195778 17441744 AFR_05460 Actinoplanes friuliensis DSM 7358 ribonuclease Z YP_008732434.1 1194849 D 1246995 CDS YP_008732435.1 556564010 17441745 1195750..1196271 1 NC_022657.1 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; putative GCN5-related N-acetyltransferase 1196271 17441745 AFR_05465 Actinoplanes friuliensis DSM 7358 putative GCN5-related N-acetyltransferase YP_008732435.1 1195750 D 1246995 CDS YP_008732436.1 556564011 17441746 complement(1196520..1196843) 1 NC_022657.1 hypothetical protein 1196843 17441746 AFR_05470 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732436.1 1196520 R 1246995 CDS YP_008732437.1 556564012 17441747 1197019..1197963 1 NC_022657.1 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain; Trypsin-like serine protease 1197963 17441747 AFR_05475 Actinoplanes friuliensis DSM 7358 Trypsin-like serine protease YP_008732437.1 1197019 D 1246995 CDS YP_008732438.1 556564013 17441748 1198054..1198362 1 NC_022657.1 hypothetical protein 1198362 17441748 AFR_05480 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732438.1 1198054 D 1246995 CDS YP_008732439.1 556564014 17441749 complement(1198973..1199626) 1 NC_022657.1 hypothetical protein 1199626 17441749 AFR_05485 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732439.1 1198973 R 1246995 CDS YP_008732440.1 556564015 17441750 complement(1199638..1199883) 1 NC_022657.1 hypothetical protein 1199883 17441750 AFR_05490 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732440.1 1199638 R 1246995 CDS YP_008732441.1 556564016 17441751 complement(1200034..1200693) 1 NC_022657.1 COG0225 Peptide methionine sulfoxide reductase; peptide-methionine (S)-S-oxide reductase 1200693 17441751 AFR_05495 Actinoplanes friuliensis DSM 7358 peptide-methionine (S)-S-oxide reductase YP_008732441.1 1200034 R 1246995 CDS YP_008732442.1 556564017 17441752 complement(1200742..1201155) 1 NC_022657.1 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases; histidine triad (HIT) protein 1201155 17441752 AFR_05500 Actinoplanes friuliensis DSM 7358 histidine triad (HIT) protein YP_008732442.1 1200742 R 1246995 CDS YP_008732443.1 556564018 17441753 1201171..1202331 1 NC_022657.1 COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases; putative cystathionine gamma-synthase 1202331 17441753 AFR_05505 Actinoplanes friuliensis DSM 7358 putative cystathionine gamma-synthase YP_008732443.1 1201171 D 1246995 CDS YP_008732444.1 556564019 17441754 1202356..1203723 1 NC_022657.1 COG0154 Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases; amidase 1203723 17441754 AFR_05510 Actinoplanes friuliensis DSM 7358 amidase YP_008732444.1 1202356 D 1246995 CDS YP_008732445.1 556564020 17441755 1203746..1204969 1 NC_022657.1 COG1171 Threonine dehydratase; threonine dehydratase 1204969 17441755 AFR_05515 Actinoplanes friuliensis DSM 7358 threonine dehydratase YP_008732445.1 1203746 D 1246995 CDS YP_008732446.1 556564021 17441756 complement(1205021..1205515) 1 NC_022657.1 COG0782 Transcription elongation factor; Transcription elongation factor greA 1205515 17441756 AFR_05520 Actinoplanes friuliensis DSM 7358 Transcription elongation factor greA YP_008732446.1 1205021 R 1246995 CDS YP_008732447.1 556564022 17441757 complement(1205644..1205988) 1 NC_022657.1 hypothetical protein 1205988 17441757 AFR_05525 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732447.1 1205644 R 1246995 CDS YP_008732448.1 556564023 17441758 1206175..1207056 1 NC_022657.1 COG2120 Uncharacterized proteins, LmbE homologs; mycothiol conjugate amidase Mca 1207056 17441758 AFR_05530 Actinoplanes friuliensis DSM 7358 mycothiol conjugate amidase Mca YP_008732448.1 1206175 D 1246995 CDS YP_008732449.1 556564024 17441759 1207075..1207431 1 NC_022657.1 hypothetical protein 1207431 17441759 AFR_05535 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732449.1 1207075 D 1246995 CDS YP_008732450.1 556564025 17441760 1207691..1210246 1 NC_022657.1 COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain; hypothetical protein 1210246 17441760 AFR_05540 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732450.1 1207691 D 1246995 CDS YP_008732451.1 556564026 17441761 1210282..1212270 1 NC_022657.1 COG1331 Highly conserved protein containing a thioredoxin domain; hypothetical protein 1212270 17441761 AFR_05545 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732451.1 1210282 D 1246995 CDS YP_008732452.1 556564027 17441762 1212365..1213480 1 NC_022657.1 COG0026 Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase); putative phosphoribosylaminoimidazole carboxylase ATPase subunit 1213480 17441762 AFR_05550 Actinoplanes friuliensis DSM 7358 putative phosphoribosylaminoimidazole carboxylase ATPase subunit YP_008732452.1 1212365 D 1246995 CDS YP_008732453.1 556564028 17441763 1213477..1213974 1 NC_022657.1 COG0041 Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase; phosphoribosylaminoimidazole carboxylase catalytic subunit 1213974 17441763 AFR_05555 Actinoplanes friuliensis DSM 7358 phosphoribosylaminoimidazole carboxylase catalytic subunit YP_008732453.1 1213477 D 1246995 CDS YP_008732454.1 556564029 17441764 complement(1215122..1220212) 1 NC_022657.1 hypothetical protein 1220212 17441764 AFR_05560 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732454.1 1215122 R 1246995 CDS YP_008732455.1 556564030 17441765 complement(1220342..1221781) 1 NC_022657.1 COG1004 Predicted UDP-glucose 6-dehydrogenase; nucleotide sugar dehydrogenase 1221781 17441765 AFR_05565 Actinoplanes friuliensis DSM 7358 nucleotide sugar dehydrogenase YP_008732455.1 1220342 R 1246995 CDS YP_008732456.1 556564031 17441766 1221954..1223108 1 NC_022657.1 COG1960 Acyl-CoA dehydrogenases; putative acyl-CoA dehydrogenase 1223108 17441766 AFR_05570 Actinoplanes friuliensis DSM 7358 putative acyl-CoA dehydrogenase YP_008732456.1 1221954 D 1246995 CDS YP_008732457.1 556564032 17441767 complement(1223113..1223739) 1 NC_022657.1 hypothetical protein 1223739 17441767 AFR_05575 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732457.1 1223113 R 1246995 CDS YP_008732458.1 556564033 17441768 complement(1223750..1225234) 1 NC_022657.1 COG0515 Serine/threonine protein kinase; Serine/threonine protein kinase 1225234 17441768 AFR_05580 Actinoplanes friuliensis DSM 7358 Serine/threonine protein kinase YP_008732458.1 1223750 R 1246995 CDS YP_008732459.1 556564034 17441769 complement(1225360..1226526) 1 NC_022657.1 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases; 2-polyprenyl-6-methoxyphenol hydroxylase-like oxidoreductase 1226526 17441769 AFR_05585 Actinoplanes friuliensis DSM 7358 2-polyprenyl-6-methoxyphenol hydroxylase-like oxidoreductase YP_008732459.1 1225360 R 1246995 CDS YP_008732460.1 556564035 17441770 complement(1226544..1227029) 1 NC_022657.1 COG1846 Transcriptional regulators; MarR family transcriptional regulator 1227029 17441770 AFR_05590 Actinoplanes friuliensis DSM 7358 MarR family transcriptional regulator YP_008732460.1 1226544 R 1246995 CDS YP_008732461.1 556564036 17441771 1227136..1227984 1 NC_022657.1 COG1396 Predicted transcriptional regulators; XRE family transcriptional regulator 1227984 17441771 AFR_05595 Actinoplanes friuliensis DSM 7358 XRE family transcriptional regulator YP_008732461.1 1227136 D 1246995 CDS YP_008732462.1 556564037 17441772 1228055..1228879 1 NC_022657.1 COG0491 Zn-dependent hydrolases, including glyoxylases; beta-lactamase class B 1228879 17441772 AFR_05600 Actinoplanes friuliensis DSM 7358 beta-lactamase class B YP_008732462.1 1228055 D 1246995 CDS YP_008732463.1 556564038 17441773 1229026..1231005 1 NC_022657.1 PBS lyase HEAT domain-containing protein repeat-containing protein 1231005 17441773 AFR_05605 Actinoplanes friuliensis DSM 7358 PBS lyase HEAT domain-containing protein repeat-containing protein YP_008732463.1 1229026 D 1246995 CDS YP_008732464.1 556564039 17441774 complement(1231006..1232901) 1 NC_022657.1 hypothetical protein 1232901 17441774 AFR_05610 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732464.1 1231006 R 1246995 CDS YP_008732465.1 556564040 17441775 1232900..1233415 1 NC_022657.1 COG1607 Acyl-CoA hydrolase; hypothetical protein 1233415 17441775 AFR_05615 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732465.1 1232900 D 1246995 CDS YP_008732466.1 556564041 17441776 1233432..1235357 1 NC_022657.1 COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases; acetoacetyl-CoA synthetase 1235357 17441776 AFR_05620 Actinoplanes friuliensis DSM 7358 acetoacetyl-CoA synthetase YP_008732466.1 1233432 D 1246995 CDS YP_008732467.1 556564042 17441777 complement(1235346..1236071) 1 NC_022657.1 COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase; hypothetical protein 1236071 17441777 AFR_05625 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732467.1 1235346 R 1246995 CDS YP_008732468.1 556564043 17441778 1236244..1237389 1 NC_022657.1 COG0438 Glycosyltransferase; putative glycosyltransferase 1237389 17441778 AFR_05630 Actinoplanes friuliensis DSM 7358 putative glycosyltransferase YP_008732468.1 1236244 D 1246995 CDS YP_008732469.1 556564044 17441779 1237435..1238550 1 NC_022657.1 COG0836 Mannose-1-phosphate guanylyltransferase; mannose-1-phosphate guanylyltransferase 1238550 17441779 AFR_05635 Actinoplanes friuliensis DSM 7358 mannose-1-phosphate guanylyltransferase YP_008732469.1 1237435 D 1246995 CDS YP_008732470.1 556564045 17441780 complement(1239317..1239865) 1 NC_022657.1 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; putative 45.4 kDa protein in thiaminase I 5'region 1239865 17441780 AFR_05640 Actinoplanes friuliensis DSM 7358 putative 45.4 kDa protein in thiaminase I 5'region YP_008732470.1 1239317 R 1246995 CDS YP_008732471.1 556564046 17441781 complement(1239881..1240885) 1 NC_022657.1 COG1478 Uncharacterized conserved protein; gamma-glutamyl ligase 1240885 17441781 AFR_05645 Actinoplanes friuliensis DSM 7358 gamma-glutamyl ligase YP_008732471.1 1239881 R 1246995 CDS YP_008732472.1 556564047 17441782 complement(1240882..1241841) 1 NC_022657.1 COG0391 Uncharacterized conserved protein; LPPG:FO 2-phospho-L-lactate transferase 1241841 17441782 AFR_05650 Actinoplanes friuliensis DSM 7358 LPPG:FO 2-phospho-L-lactate transferase YP_008732472.1 1240882 R 1246995 CDS YP_008732473.1 556564048 17441783 1242006..1242920 1 NC_022657.1 Protein piccolo 1242920 17441783 AFR_05655 Actinoplanes friuliensis DSM 7358 Protein piccolo YP_008732473.1 1242006 D 1246995 CDS YP_008732474.1 556564049 17441784 1243055..1245562 1 NC_022657.1 COG1060 Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes; FO synthase 1245562 fbiC 17441784 fbiC Actinoplanes friuliensis DSM 7358 FO synthase YP_008732474.1 1243055 D 1246995 CDS YP_008732475.1 556564050 17441785 1245866..1246123 1 NC_022657.1 transcription factor WhiB 1246123 17441785 AFR_05665 Actinoplanes friuliensis DSM 7358 transcription factor WhiB YP_008732475.1 1245866 D 1246995 CDS YP_008732476.1 556564051 17441786 complement(1246156..1246521) 1 NC_022657.1 hypothetical protein 1246521 17441786 AFR_05670 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732476.1 1246156 R 1246995 CDS YP_008732477.1 556564052 17441787 1246860..1247225 1 NC_022657.1 hypothetical protein 1247225 17441787 AFR_05675 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732477.1 1246860 D 1246995 CDS YP_008732478.1 556564053 17441788 complement(1248110..1248970) 1 NC_022657.1 COG0726 Predicted xylanase/chitin deacetylase; polysaccharide deacetylase 1248970 17441788 AFR_05680 Actinoplanes friuliensis DSM 7358 polysaccharide deacetylase YP_008732478.1 1248110 R 1246995 CDS YP_008732479.1 556564054 17441789 complement(1249131..1249688) 1 NC_022657.1 hypothetical protein 1249688 17441789 AFR_05685 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732479.1 1249131 R 1246995 CDS YP_008732480.1 556564055 17441790 complement(1249799..1251235) 1 NC_022657.1 COG1012 NAD-dependent aldehyde dehydrogenases; aldehyde dehydrogenase 1251235 17441790 AFR_05690 Actinoplanes friuliensis DSM 7358 aldehyde dehydrogenase YP_008732480.1 1249799 R 1246995 CDS YP_008732481.1 556564056 17441791 1251328..1252632 1 NC_022657.1 COG3284 Transcriptional activator of acetoin/glycerol metabolism; putative transcriptional regulator 1252632 17441791 AFR_05695 Actinoplanes friuliensis DSM 7358 putative transcriptional regulator YP_008732481.1 1251328 D 1246995 CDS YP_008732482.1 556564057 17441792 1252775..1254298 1 NC_022657.1 COG1012 NAD-dependent aldehyde dehydrogenases; aldehyde dehydrogenase 1254298 17441792 AFR_05700 Actinoplanes friuliensis DSM 7358 aldehyde dehydrogenase YP_008732482.1 1252775 D 1246995 CDS YP_008732483.1 556564058 17441793 1254320..1254676 1 NC_022657.1 COG3564 Uncharacterized protein conserved in bacteria; hypothetical protein 1254676 17441793 AFR_05705 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732483.1 1254320 D 1246995 CDS YP_008732484.1 556564059 17441794 1254792..1255421 1 NC_022657.1 COG1515 Deoxyinosine 3'endonuclease (endonuclease V); putative endonuclease V 1255421 17441794 AFR_05710 Actinoplanes friuliensis DSM 7358 putative endonuclease V YP_008732484.1 1254792 D 1246995 CDS YP_008732485.1 556564060 17441795 1255521..1256900 1 NC_022657.1 COG1109 Phosphomannomutase; phosphomannomutase 1256900 17441795 AFR_05715 Actinoplanes friuliensis DSM 7358 phosphomannomutase YP_008732485.1 1255521 D 1246995 CDS YP_008732486.1 556564061 17441796 1256949..1257131 1 NC_022657.1 COG2835 Uncharacterized conserved protein; hypothetical protein 1257131 17441796 AFR_05720 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732486.1 1256949 D 1246995 CDS YP_008732487.1 556564062 17441797 1257131..1258354 1 NC_022657.1 COG0794 Predicted sugar phosphate isomerase involved in capsule formation; Glucosamine 6-phosphate synthetase 1258354 17441797 AFR_05725 Actinoplanes friuliensis DSM 7358 Glucosamine 6-phosphate synthetase YP_008732487.1 1257131 D 1246995 CDS YP_008732488.1 556564063 17441798 1258351..1259307 1 NC_022657.1 COG0053 Predicted Co/Zn/Cd cation transporters; Zinc transporter 9 1259307 17441798 AFR_05730 Actinoplanes friuliensis DSM 7358 Zinc transporter 9 YP_008732488.1 1258351 D 1246995 CDS YP_008732489.1 556564064 17441799 1259324..1260514 1 NC_022657.1 COG1482 Phosphomannose isomerase; mannose-6-phosphate isomerase 1260514 17441799 AFR_05735 Actinoplanes friuliensis DSM 7358 mannose-6-phosphate isomerase YP_008732489.1 1259324 D 1246995 CDS YP_008732490.1 556564065 17441800 1261507..1262376 1 NC_022657.1 putative DNA-binding protein 1262376 17441800 AFR_05740 Actinoplanes friuliensis DSM 7358 putative DNA-binding protein YP_008732490.1 1261507 D 1246995 CDS YP_008732491.1 556564066 17441801 1262441..1262623 1 NC_022657.1 hypothetical protein 1262623 17441801 AFR_05745 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732491.1 1262441 D 1246995 CDS YP_008732492.1 556564067 17441802 1262764..1263636 1 NC_022657.1 COG0672 High-affinity Fe2+/Pb2+ permease; iron permease ftr1 1263636 17441802 AFR_05750 Actinoplanes friuliensis DSM 7358 iron permease ftr1 YP_008732492.1 1262764 D 1246995 CDS YP_008732493.1 556564068 17441803 1263649..1264794 1 NC_022657.1 COG2822 Predicted periplasmic lipoprotein involved in iron transport; peptidase M75, Imelysin 1264794 17441803 AFR_05755 Actinoplanes friuliensis DSM 7358 peptidase M75, Imelysin YP_008732493.1 1263649 D 1246995 CDS YP_008732494.1 556564069 17441804 1264805..1266079 1 NC_022657.1 COG2837 Predicted iron-dependent peroxidase; Dyp-type peroxidase family protein 1266079 17441804 AFR_05760 Actinoplanes friuliensis DSM 7358 Dyp-type peroxidase family protein YP_008732494.1 1264805 D 1246995 CDS YP_008732495.1 556564070 17441805 1266183..1266872 1 NC_022657.1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Transcriptional regulatory protein yycF 1266872 17441805 AFR_05765 Actinoplanes friuliensis DSM 7358 Transcriptional regulatory protein yycF YP_008732495.1 1266183 D 1246995 CDS YP_008732496.1 556564071 17441806 1266972..1268618 1 NC_022657.1 COG0642 Signal transduction histidine kinase; putative two-component system sensor kinase 1268618 17441806 AFR_05770 Actinoplanes friuliensis DSM 7358 putative two-component system sensor kinase YP_008732496.1 1266972 D 1246995 CDS YP_008732497.1 556564072 17441807 1268615..1270441 1 NC_022657.1 COG0418 Dihydroorotase; hypothetical protein 1270441 17441807 AFR_05775 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732497.1 1268615 D 1246995 CDS YP_008732498.1 556564073 17441808 1270452..1271276 1 NC_022657.1 hypothetical protein 1271276 17441808 AFR_05780 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732498.1 1270452 D 1246995 CDS YP_008732499.1 556564074 17441809 1271517..1272137 1 NC_022657.1 COG1544 Ribosome-associated protein Y (PSrp-1); sigma 54 modulation protein/ribosomal protein S30EA 1272137 17441809 AFR_05785 Actinoplanes friuliensis DSM 7358 sigma 54 modulation protein/ribosomal protein S30EA YP_008732499.1 1271517 D 1246995 CDS YP_008732500.1 556564075 17441810 complement(1272180..1273313) 1 NC_022657.1 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins; putative GMP synthase 1273313 17441810 AFR_05790 Actinoplanes friuliensis DSM 7358 putative GMP synthase YP_008732500.1 1272180 R 1246995 CDS YP_008732501.1 556564076 17441811 complement(1273310..1274431) 1 NC_022657.1 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins; GCN5-like N-acetyltransferase 1274431 17441811 AFR_05795 Actinoplanes friuliensis DSM 7358 GCN5-like N-acetyltransferase YP_008732501.1 1273310 R 1246995 CDS YP_008732502.1 556564077 17441812 1274615..1277500 1 NC_022657.1 COG0653 Preprotein translocase subunit SecA (ATPase, RNA helicase); putative preprotein translocase SecA subunit 1277500 17441812 AFR_05800 Actinoplanes friuliensis DSM 7358 putative preprotein translocase SecA subunit YP_008732502.1 1274615 D 1246995 CDS YP_008732503.1 556564078 17441813 complement(1280249..1280461) 1 NC_022657.1 COG1910 Periplasmic molybdate-binding protein/domain; excisionase family DNA binding domain-containing protein 1280461 17441813 AFR_05805 Actinoplanes friuliensis DSM 7358 excisionase family DNA binding domain-containing protein YP_008732503.1 1280249 R 1246995 CDS YP_008732504.1 556564079 17441814 complement(1280523..1280975) 1 NC_022657.1 COG1522 Transcriptional regulators; AsnC family transcriptional regulator 1280975 17441814 AFR_05810 Actinoplanes friuliensis DSM 7358 AsnC family transcriptional regulator YP_008732504.1 1280523 R 1246995 CDS YP_008732505.1 556564080 17441815 1281068..1281490 1 NC_022657.1 COG0607 Rhodanese-related sulfurtransferase; thiosulfate:cyanide sulfurtransferase 1281490 17441815 AFR_05815 Actinoplanes friuliensis DSM 7358 thiosulfate:cyanide sulfurtransferase YP_008732505.1 1281068 D 1246995 CDS YP_008732506.1 556564081 17441816 1281560..1282069 1 NC_022657.1 hypothetical protein 1282069 17441816 AFR_05820 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732506.1 1281560 D 1246995 CDS YP_008732507.1 556564082 17441817 complement(1282044..1283066) 1 NC_022657.1 Zinc finger and BTB domain-containing protein 17 1283066 17441817 AFR_05825 Actinoplanes friuliensis DSM 7358 Zinc finger and BTB domain-containing protein 17 YP_008732507.1 1282044 R 1246995 CDS YP_008732508.1 556564083 17441818 1283201..1284829 1 NC_022657.1 COG1012 NAD-dependent aldehyde dehydrogenases; delta-1-pyrroline-5-carboxylate dehydrogenase 1284829 17441818 AFR_05830 Actinoplanes friuliensis DSM 7358 delta-1-pyrroline-5-carboxylate dehydrogenase YP_008732508.1 1283201 D 1246995 CDS YP_008732509.1 556564084 17441819 1285169..1285621 1 NC_022657.1 COG1695 Predicted transcriptional regulators; putative PadR-like family transcriptional regulator 1285621 17441819 AFR_05835 Actinoplanes friuliensis DSM 7358 putative PadR-like family transcriptional regulator YP_008732509.1 1285169 D 1246995 CDS YP_008732510.1 556564085 17441820 1285688..1286803 1 NC_022657.1 COG1186 Protein chain release factor B; peptide chain release factor 2 1286803 prfB 17441820 prfB Actinoplanes friuliensis DSM 7358 peptide chain release factor 2 YP_008732510.1 1285688 D 1246995 CDS YP_008732511.1 556564086 17441821 1286965..1287645 1 NC_022657.1 COG2884 Predicted ATPase involved in cell division; putative cell division ATP-binding protein FtsE 1287645 17441821 AFR_05845 Actinoplanes friuliensis DSM 7358 putative cell division ATP-binding protein FtsE YP_008732511.1 1286965 D 1246995 CDS YP_008732512.1 556564087 17441822 1287709..1288584 1 NC_022657.1 COG2177 Cell division protein; cell division protein FtsX 1288584 17441822 AFR_05850 Actinoplanes friuliensis DSM 7358 cell division protein FtsX YP_008732512.1 1287709 D 1246995 CDS YP_008732513.1 556564088 17441823 1288751..1289953 1 NC_022657.1 COG0791 Cell wall-associated hydrolases (invasion-associated proteins); Pyruvate decarboxylase isozyme 2 1289953 17441823 AFR_05855 Actinoplanes friuliensis DSM 7358 Pyruvate decarboxylase isozyme 2 YP_008732513.1 1288751 D 1246995 CDS YP_008732514.1 556564089 17441824 1290030..1290506 1 NC_022657.1 COG0691 tmRNA-binding protein; SsrA-binding protein 1290506 17441824 AFR_05860 Actinoplanes friuliensis DSM 7358 SsrA-binding protein YP_008732514.1 1290030 D 1246995 CDS YP_008732515.1 556564090 17441825 1290553..1291224 1 NC_022657.1 glycoside hydrolase 1291224 17441825 AFR_05865 Actinoplanes friuliensis DSM 7358 glycoside hydrolase YP_008732515.1 1290553 D 1246995 CDS YP_008732516.1 556564091 17441826 1292215..1292934 1 NC_022657.1 COG0346 Lactoylglutathione lyase and related lyases; hypothetical protein 1292934 17441826 AFR_05870 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732516.1 1292215 D 1246995 CDS YP_008732517.1 556564092 17441827 complement(1292961..1293632) 1 NC_022657.1 COG1960 Acyl-CoA dehydrogenases; hypothetical protein 1293632 17441827 AFR_05875 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732517.1 1292961 R 1246995 CDS YP_008732518.1 556564093 17441828 1293756..1294547 1 NC_022657.1 COG2771 DNA-binding HTH domain-containing proteins; LuxR family transcriptional regulator 1294547 17441828 AFR_05880 Actinoplanes friuliensis DSM 7358 LuxR family transcriptional regulator YP_008732518.1 1293756 D 1246995 CDS YP_008732519.1 556564094 17441829 complement(1294544..1295233) 1 NC_022657.1 hypothetical protein 1295233 17441829 AFR_05885 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732519.1 1294544 R 1246995 CDS YP_008732520.1 556564095 17441830 complement(1295264..1296070) 1 NC_022657.1 COG0005 Purine nucleoside phosphorylase; 5'-methylthioadenosine phosphorylase 1296070 17441830 AFR_05890 Actinoplanes friuliensis DSM 7358 5'-methylthioadenosine phosphorylase YP_008732520.1 1295264 R 1246995 CDS YP_008732521.1 556564096 17441831 1296196..1296753 1 NC_022657.1 COG1678 Putative transcriptional regulator; hypothetical protein 1296753 17441831 AFR_05895 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732521.1 1296196 D 1246995 CDS YP_008732522.1 556564097 17441833 1296992..1297567 1 NC_022657.1 hypothetical protein 1297567 17441833 AFR_05900 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732522.1 1296992 D 1246995 CDS YP_008732523.1 556564098 17441834 complement(1297582..1297875) 1 NC_022657.1 hypothetical protein 1297875 17441834 AFR_05905 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732523.1 1297582 R 1246995 CDS YP_008732524.1 556564099 17441835 complement(1297872..1300664) 1 NC_022657.1 COG3903 Predicted ATPase; transcriptional activator domain-containing protein 1300664 17441835 AFR_05910 Actinoplanes friuliensis DSM 7358 transcriptional activator domain-containing protein YP_008732524.1 1297872 R 1246995 CDS YP_008732525.1 556564100 17441836 complement(1300813..1301772) 1 NC_022657.1 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs; CdaR family transcriptional regulator 1301772 17441836 AFR_05915 Actinoplanes friuliensis DSM 7358 CdaR family transcriptional regulator YP_008732525.1 1300813 R 1246995 CDS YP_008732526.1 556564101 17441837 complement(1301782..1302762) 1 NC_022657.1 COG0657 Esterase/lipase; alpha/beta hydrolase 1302762 17441837 AFR_05920 Actinoplanes friuliensis DSM 7358 alpha/beta hydrolase YP_008732526.1 1301782 R 1246995 CDS YP_008732527.1 556564102 17441838 1302945..1303853 1 NC_022657.1 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases; f420-dependent oxidoreductase 1303853 17441838 AFR_05925 Actinoplanes friuliensis DSM 7358 f420-dependent oxidoreductase YP_008732527.1 1302945 D 1246995 CDS YP_008732528.1 556564103 17441839 complement(1303858..1304508) 1 NC_022657.1 COG1802 Transcriptional regulators; GntR family transcriptional regulator 1304508 17441839 AFR_05930 Actinoplanes friuliensis DSM 7358 GntR family transcriptional regulator YP_008732528.1 1303858 R 1246995 CDS YP_008732529.1 556564104 17441840 1304583..1305887 1 NC_022657.1 COG1520 FOG: WD40-like repeat; hypothetical protein 1305887 17441840 AFR_05935 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732529.1 1304583 D 1246995 CDS YP_008732530.1 556564105 17441841 1305936..1306514 1 NC_022657.1 COG0789 Predicted transcriptional regulators; transcriptional regulator 1306514 17441841 AFR_05940 Actinoplanes friuliensis DSM 7358 transcriptional regulator YP_008732530.1 1305936 D 1246995 CDS YP_008732531.1 556564106 17441842 complement(1306516..1306722) 1 NC_022657.1 hypothetical protein 1306722 17441842 AFR_05945 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732531.1 1306516 R 1246995 CDS YP_008732532.1 556564107 17441843 complement(1306722..1307348) 1 NC_022657.1 hypothetical protein 1307348 17441843 AFR_05950 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732532.1 1306722 R 1246995 CDS YP_008732533.1 556564108 17441844 complement(1307345..1307788) 1 NC_022657.1 hypothetical protein 1307788 17441844 AFR_05955 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732533.1 1307345 R 1246995 CDS YP_008732534.1 556564109 17441845 complement(1307801..1308418) 1 NC_022657.1 hypothetical protein 1308418 17441845 AFR_05960 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732534.1 1307801 R 1246995 CDS YP_008732535.1 556564110 17441846 complement(1308418..1309131) 1 NC_022657.1 hypothetical protein 1309131 17441846 AFR_05965 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732535.1 1308418 R 1246995 CDS YP_008732536.1 556564111 17441847 complement(1309131..1310156) 1 NC_022657.1 COG4972 Tfp pilus assembly protein, ATPase PilM; type IV pilus assembly protein PilM 1310156 17441847 AFR_05970 Actinoplanes friuliensis DSM 7358 type IV pilus assembly protein PilM YP_008732536.1 1309131 R 1246995 CDS YP_008732537.1 556564112 17441848 complement(1310175..1310957) 1 NC_022657.1 COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases; putative prepilin peptidase 1310957 17441848 AFR_05975 Actinoplanes friuliensis DSM 7358 putative prepilin peptidase YP_008732537.1 1310175 R 1246995 CDS YP_008732538.1 556564113 17441849 complement(1311006..1311485) 1 NC_022657.1 putative type IV pilin PilA 1311485 17441849 AFR_05980 Actinoplanes friuliensis DSM 7358 putative type IV pilin PilA YP_008732538.1 1311006 R 1246995 CDS YP_008732539.1 556564114 17441850 complement(1311591..1312823) 1 NC_022657.1 COG1459 Type II secretory pathway, component PulF; putative type IV pilus biogenesis protein PilC 1312823 17441850 AFR_05985 Actinoplanes friuliensis DSM 7358 putative type IV pilus biogenesis protein PilC YP_008732539.1 1311591 R 1246995 CDS YP_008732540.1 556564115 17441851 complement(1312825..1313961) 1 NC_022657.1 COG2805 Tfp pilus assembly protein, pilus retraction ATPase PilT; Twitching motility protein 1313961 17441851 AFR_05990 Actinoplanes friuliensis DSM 7358 Twitching motility protein YP_008732540.1 1312825 R 1246995 CDS YP_008732541.1 556564116 17441852 complement(1314089..1315753) 1 NC_022657.1 COG2804 Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB; type II secretion system protein E 1315753 17441852 AFR_05995 Actinoplanes friuliensis DSM 7358 type II secretion system protein E YP_008732541.1 1314089 R 1246995 CDS YP_008732542.1 556564117 17441853 complement(1315836..1316822) 1 NC_022657.1 COG4977 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain; HTH-type transcriptional regulator glxA 1316822 17441853 AFR_06000 Actinoplanes friuliensis DSM 7358 HTH-type transcriptional regulator glxA YP_008732542.1 1315836 R 1246995 CDS YP_008732543.1 556564118 17441854 1316872..1318215 1 NC_022657.1 COG0477 Permeases of the major facilitator superfamily; putative MFS transporter 1318215 17441854 AFR_06005 Actinoplanes friuliensis DSM 7358 putative MFS transporter YP_008732543.1 1316872 D 1246995 CDS YP_008732544.1 556564119 17441855 1318274..1318804 1 NC_022657.1 putative secreted metallopeptidase 1318804 17441855 AFR_06010 Actinoplanes friuliensis DSM 7358 putative secreted metallopeptidase YP_008732544.1 1318274 D 1246995 CDS YP_008732545.1 556564120 17441856 complement(1318823..1319779) 1 NC_022657.1 hypothetical protein 1319779 17441856 AFR_06015 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732545.1 1318823 R 1246995 CDS YP_008732546.1 556564121 17441857 complement(1319780..1320097) 1 NC_022657.1 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); Anti-sigma F factor antagonist 1320097 17441857 AFR_06020 Actinoplanes friuliensis DSM 7358 Anti-sigma F factor antagonist YP_008732546.1 1319780 R 1246995 CDS YP_008732547.1 556564122 17441858 1320202..1322622 1 NC_022657.1 COG0457 FOG: TPR repeat; Nephrocystin-3 1322622 17441858 AFR_06025 Actinoplanes friuliensis DSM 7358 Nephrocystin-3 YP_008732547.1 1320202 D 1246995 CDS YP_008732548.1 556564123 17441859 complement(1322619..1322993) 1 NC_022657.1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; response regulator 1322993 17441859 AFR_06030 Actinoplanes friuliensis DSM 7358 response regulator YP_008732548.1 1322619 R 1246995 CDS YP_008732549.1 556564124 17441860 complement(1323013..1325130) 1 NC_022657.1 COG0642 Signal transduction histidine kinase; putative multi-sensor signal transduction histidine kinase 1325130 17441860 AFR_06035 Actinoplanes friuliensis DSM 7358 putative multi-sensor signal transduction histidine kinase YP_008732549.1 1323013 R 1246995 CDS YP_008732550.1 556564125 17441861 1325346..1325768 1 NC_022657.1 COG0784 FOG: CheY-like receiver; putative response regulator receiver domain protein 1325768 17441861 AFR_06040 Actinoplanes friuliensis DSM 7358 putative response regulator receiver domain protein YP_008732550.1 1325346 D 1246995 CDS YP_008732551.1 556564126 17441862 complement(1326097..1326546) 1 NC_022657.1 COG1846 Transcriptional regulators; MarR family transcriptional regulator 1326546 17441862 AFR_06045 Actinoplanes friuliensis DSM 7358 MarR family transcriptional regulator YP_008732551.1 1326097 R 1246995 CDS YP_008732552.1 556564127 17441863 1326638..1327360 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); short-chain dehydrogenase/reductase SDR 1327360 17441863 AFR_06050 Actinoplanes friuliensis DSM 7358 short-chain dehydrogenase/reductase SDR YP_008732552.1 1326638 D 1246995 CDS YP_008732553.1 556564128 17441864 complement(1327570..1329258) 1 NC_022657.1 COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain; putative signaling protein 1329258 17441864 AFR_06055 Actinoplanes friuliensis DSM 7358 putative signaling protein YP_008732553.1 1327570 R 1246995 CDS YP_008732554.1 556564129 17441865 complement(1329315..1330748) 1 NC_022657.1 hypothetical protein 1330748 17441865 AFR_06060 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732554.1 1329315 R 1246995 CDS YP_008732555.1 556564130 17441866 complement(1330780..1330986) 1 NC_022657.1 hypothetical protein 1330986 17441866 AFR_06065 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732555.1 1330780 R 1246995 CDS YP_008732556.1 556564131 17441867 1331191..1331388 1 NC_022657.1 hypothetical protein 1331388 17441867 AFR_06070 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732556.1 1331191 D 1246995 CDS YP_008732557.1 556564132 17441868 1331441..1331773 1 NC_022657.1 hypothetical protein 1331773 17441868 AFR_06075 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732557.1 1331441 D 1246995 CDS YP_008732558.1 556564133 17441869 complement(1331813..1332097) 1 NC_022657.1 COG2343 Uncharacterized protein conserved in bacteria; hypothetical protein 1332097 17441869 AFR_06080 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732558.1 1331813 R 1246995 CDS YP_008732559.1 556564134 17441870 1332251..1332835 1 NC_022657.1 hypothetical protein 1332835 17441870 AFR_06085 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732559.1 1332251 D 1246995 CDS YP_008732560.1 556564135 17441871 1332832..1333899 1 NC_022657.1 hypothetical protein 1333899 17441871 AFR_06090 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732560.1 1332832 D 1246995 CDS YP_008732561.1 556564136 17441872 1333896..1335380 1 NC_022657.1 hypothetical protein 1335380 17441872 AFR_06095 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732561.1 1333896 D 1246995 CDS YP_008732562.1 556564137 17441873 complement(1335357..1337165) 1 NC_022657.1 COG2203 FOG: GAF domain; Phosphoserine phosphatase rsbP 1337165 17441873 AFR_06100 Actinoplanes friuliensis DSM 7358 Phosphoserine phosphatase rsbP YP_008732562.1 1335357 R 1246995 CDS YP_008732563.1 556564138 17441874 complement(1337245..1337898) 1 NC_022657.1 activator of Hsp90 ATPase 1 family protein 1337898 17441874 AFR_06105 Actinoplanes friuliensis DSM 7358 activator of Hsp90 ATPase 1 family protein YP_008732563.1 1337245 R 1246995 CDS YP_008732564.1 556564139 17441875 complement(1337960..1338817) 1 NC_022657.1 putative DNA primase 1338817 17441875 AFR_06110 Actinoplanes friuliensis DSM 7358 putative DNA primase YP_008732564.1 1337960 R 1246995 CDS YP_008732565.1 556564140 17441876 1338883..1339398 1 NC_022657.1 hypothetical protein 1339398 17441876 AFR_06115 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732565.1 1338883 D 1246995 CDS YP_008732566.1 556564141 17441877 1339484..1340332 1 NC_022657.1 hypothetical protein 1340332 17441877 AFR_06120 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732566.1 1339484 D 1246995 CDS YP_008732567.1 556564142 17441878 complement(1340325..1341332) 1 NC_022657.1 hypothetical protein 1341332 17441878 AFR_06125 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732567.1 1340325 R 1246995 CDS YP_008732568.1 556564143 17441879 1341394..1342743 1 NC_022657.1 COG1112 Superfamily I DNA and RNA helicases and helicase subunits; hypothetical protein 1342743 17441879 AFR_06130 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732568.1 1341394 D 1246995 CDS YP_008732569.1 556564144 17441880 1342816..1343217 1 NC_022657.1 hypothetical protein 1343217 17441880 AFR_06135 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732569.1 1342816 D 1246995 CDS YP_008732570.1 556564145 17441881 complement(1343261..1343452) 1 NC_022657.1 hypothetical protein 1343452 17441881 AFR_06140 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732570.1 1343261 R 1246995 CDS YP_008732571.1 556564146 17441882 1344737..1345546 1 NC_022657.1 COG1404 Subtilisin-like serine proteases; Subtilisin-like serine protease pepC 1345546 17441882 AFR_06145 Actinoplanes friuliensis DSM 7358 Subtilisin-like serine protease pepC YP_008732571.1 1344737 D 1246995 CDS YP_008732572.1 556564147 17441883 complement(1345515..1346732) 1 NC_022657.1 hypothetical protein 1346732 17441883 AFR_06150 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732572.1 1345515 R 1246995 CDS YP_008732573.1 556564148 17441884 1347115..1347747 1 NC_022657.1 hypothetical protein 1347747 17441884 AFR_06155 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732573.1 1347115 D 1246995 CDS YP_008732574.1 556564149 17441885 complement(1347801..1348538) 1 NC_022657.1 COG1309 Transcriptional regulator; TetR family transcriptional regulator 1348538 17441885 AFR_06160 Actinoplanes friuliensis DSM 7358 TetR family transcriptional regulator YP_008732574.1 1347801 R 1246995 CDS YP_008732575.1 556564150 17441886 1348608..1349519 1 NC_022657.1 COG1131 ABC-type multidrug transport system, ATPase component; daunorubicin resistance ABC transporter ATPase 1349519 17441886 AFR_06165 Actinoplanes friuliensis DSM 7358 daunorubicin resistance ABC transporter ATPase YP_008732575.1 1348608 D 1246995 CDS YP_008732576.1 556564151 17441887 1349523..1350272 1 NC_022657.1 COG0842 ABC-type multidrug transport system, permease component; ABC transporter 1350272 17441887 AFR_06170 Actinoplanes friuliensis DSM 7358 ABC transporter YP_008732576.1 1349523 D 1246995 CDS YP_008732577.1 556564152 17441888 1350345..1351058 1 NC_022657.1 COG1802 Transcriptional regulators; GntR family transcriptional regulator 1351058 17441888 AFR_06175 Actinoplanes friuliensis DSM 7358 GntR family transcriptional regulator YP_008732577.1 1350345 D 1246995 CDS YP_008732578.1 556564153 17441889 1351190..1352719 1 NC_022657.1 COG1953 Cytosine/uracil/thiamine/allantoin permeases; allantoin permease 1352719 17441889 AFR_06180 Actinoplanes friuliensis DSM 7358 allantoin permease YP_008732578.1 1351190 D 1246995 CDS YP_008732579.1 556564154 17441890 1352722..1353450 1 NC_022657.1 COG4126 Hydantoin racemase; hydantoin racemase 1353450 17441890 AFR_06185 Actinoplanes friuliensis DSM 7358 hydantoin racemase YP_008732579.1 1352722 D 1246995 CDS YP_008732580.1 556564155 17441891 1353554..1354564 1 NC_022657.1 COG2515 1-aminocyclopropane-1-carboxylate deaminase; 1-aminocyclopropane-1-carboxylate deaminase 1354564 17441891 AFR_06190 Actinoplanes friuliensis DSM 7358 1-aminocyclopropane-1-carboxylate deaminase YP_008732580.1 1353554 D 1246995 CDS YP_008732581.1 556564156 17441892 1354579..1355325 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); short-chain dehydrogenase/reductase sdr 1355325 17441892 AFR_06195 Actinoplanes friuliensis DSM 7358 short-chain dehydrogenase/reductase sdr YP_008732581.1 1354579 D 1246995 CDS YP_008732582.1 556564157 17441893 complement(1355333..1356130) 1 NC_022657.1 hypothetical protein 1356130 17441893 AFR_06200 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732582.1 1355333 R 1246995 CDS YP_008732583.1 556564158 17441894 1356198..1360439 1 NC_022657.1 COG1112 Superfamily I DNA and RNA helicases and helicase subunits; hypothetical protein 1360439 17441894 AFR_06205 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732583.1 1356198 D 1246995 CDS YP_008732584.1 556564159 17441895 complement(1360357..1361295) 1 NC_022657.1 COG4977 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain; AraC family transcriptional regulator 1361295 17441895 AFR_06210 Actinoplanes friuliensis DSM 7358 AraC family transcriptional regulator YP_008732584.1 1360357 R 1246995 CDS YP_008732585.1 556564160 17441896 1361378..1361761 1 NC_022657.1 COG0662 Mannose-6-phosphate isomerase; Cupin 2 barrel domain-containing protein 1361761 17441896 AFR_06215 Actinoplanes friuliensis DSM 7358 Cupin 2 barrel domain-containing protein YP_008732585.1 1361378 D 1246995 CDS YP_008732586.1 556564161 17441897 complement(1361751..1363343) 1 NC_022657.1 mrr restriction system protein 1363343 17441897 AFR_06220 Actinoplanes friuliensis DSM 7358 mrr restriction system protein YP_008732586.1 1361751 R 1246995 CDS YP_008732587.1 556564162 17441898 1363792..1365489 1 NC_022657.1 COG2202 FOG: PAS/PAC domain; putative diguanylate cyclase/phosphodiesterase with PAS sensor 1365489 17441898 AFR_06225 Actinoplanes friuliensis DSM 7358 putative diguanylate cyclase/phosphodiesterase with PAS sensor YP_008732587.1 1363792 D 1246995 CDS YP_008732588.1 556564163 17441899 1365508..1365897 1 NC_022657.1 COG0662 Mannose-6-phosphate isomerase; hypothetical protein 1365897 17441899 AFR_06230 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732588.1 1365508 D 1246995 CDS YP_008732589.1 556564164 17441900 1366266..1366739 1 NC_022657.1 COG1846 Transcriptional regulators; putative MarR-family transcriptional regulator 1366739 17441900 AFR_06235 Actinoplanes friuliensis DSM 7358 putative MarR-family transcriptional regulator YP_008732589.1 1366266 D 1246995 CDS YP_008732590.1 556564165 17441901 1367491..1367700 1 NC_022657.1 hypothetical protein 1367700 17441901 AFR_06240 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732590.1 1367491 D 1246995 CDS YP_008732591.1 556564166 17441902 complement(1368292..1370238) 1 NC_022657.1 hypothetical protein 1370238 17441902 AFR_06245 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732591.1 1368292 R 1246995 CDS YP_008732592.1 556564167 17441903 1370303..1371388 1 NC_022657.1 COG1062 Zn-dependent alcohol dehydrogenases, class III; mycothiol-dependent formaldehyde dehydrogenase 1371388 17441903 AFR_06250 Actinoplanes friuliensis DSM 7358 mycothiol-dependent formaldehyde dehydrogenase YP_008732592.1 1370303 D 1246995 CDS YP_008732593.1 556564168 17441904 1371388..1371969 1 NC_022657.1 COG0491 Zn-dependent hydrolases, including glyoxylases; hydroxyacylglutathione hydrolase 1371969 17441904 AFR_06255 Actinoplanes friuliensis DSM 7358 hydroxyacylglutathione hydrolase YP_008732593.1 1371388 D 1246995 CDS YP_008732594.1 556564169 17441905 complement(1371966..1373312) 1 NC_022657.1 COG3408 Glycogen debranching enzyme; hypothetical protein 1373312 17441905 AFR_06260 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732594.1 1371966 R 1246995 CDS YP_008732595.1 556564170 17441906 1373536..1375029 1 NC_022657.1 hypothetical protein 1375029 17441906 AFR_06265 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732595.1 1373536 D 1246995 CDS YP_008732596.1 556564171 17441907 complement(1375043..1376110) 1 NC_022657.1 COG1793 ATP-dependent DNA ligase; putative ATP-dependent DNA ligase 1376110 17441907 AFR_06270 Actinoplanes friuliensis DSM 7358 putative ATP-dependent DNA ligase YP_008732596.1 1375043 R 1246995 CDS YP_008732597.1 556564172 17441908 1376183..1376848 1 NC_022657.1 COG2207 AraC-type DNA-binding domain-containing proteins; AraC family transcriptional regulator 1376848 17441908 AFR_06275 Actinoplanes friuliensis DSM 7358 AraC family transcriptional regulator YP_008732597.1 1376183 D 1246995 CDS YP_008732598.1 556564173 17441909 1377020..1378129 1 NC_022657.1 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases; putative FAD-dependent monooxygenase 1378129 17441909 AFR_06280 Actinoplanes friuliensis DSM 7358 putative FAD-dependent monooxygenase YP_008732598.1 1377020 D 1246995 CDS YP_008732599.1 556564174 17441910 1378253..1380010 1 NC_022657.1 COG0843 Heme/copper-type cytochrome/quinol oxidases, subunit 1; putative cytochrome c oxidase subunit I 1380010 17441910 AFR_06285 Actinoplanes friuliensis DSM 7358 putative cytochrome c oxidase subunit I YP_008732599.1 1378253 D 1246995 CDS YP_008732600.1 556564175 17441911 complement(1380214..1380828) 1 NC_022657.1 COG1309 Transcriptional regulator; transcriptional regulatory protein 1380828 17441911 AFR_06290 Actinoplanes friuliensis DSM 7358 transcriptional regulatory protein YP_008732600.1 1380214 R 1246995 CDS YP_008732601.1 556564176 17441912 1381035..1382399 1 NC_022657.1 COG0477 Permeases of the major facilitator superfamily; putative drug resistance protein 1382399 17441912 AFR_06295 Actinoplanes friuliensis DSM 7358 putative drug resistance protein YP_008732601.1 1381035 D 1246995 CDS YP_008732602.1 556564177 17441913 1382396..1383022 1 NC_022657.1 COG0702 Predicted nucleoside-diphosphate-sugar epimerases; NAD-dependent glycerol-3-phosphate dehydrogenase domain-containing protein 1383022 17441913 AFR_06300 Actinoplanes friuliensis DSM 7358 NAD-dependent glycerol-3-phosphate dehydrogenase domain-containing protein YP_008732602.1 1382396 D 1246995 CDS YP_008732603.1 556564178 17441914 complement(1383110..1384420) 1 NC_022657.1 COG0477 Permeases of the major facilitator superfamily; putative MFS transporter 1384420 17441914 AFR_06305 Actinoplanes friuliensis DSM 7358 putative MFS transporter YP_008732603.1 1383110 R 1246995 CDS YP_008732604.1 556564179 17441915 complement(1384478..1385053) 1 NC_022657.1 COG1335 Amidases related to nicotinamidase; isochorismatase hydrolase 1385053 17441915 AFR_06310 Actinoplanes friuliensis DSM 7358 isochorismatase hydrolase YP_008732604.1 1384478 R 1246995 CDS YP_008732605.1 556564180 17441916 complement(1385064..1386353) 1 NC_022657.1 COG1488 Nicotinic acid phosphoribosyltransferase; nicotinate phosphoribosyltransferase 1386353 17441916 AFR_06315 Actinoplanes friuliensis DSM 7358 nicotinate phosphoribosyltransferase YP_008732605.1 1385064 R 1246995 CDS YP_008732606.1 556564181 17441917 complement(1386364..1388955) 1 NC_022657.1 COG0542 ATPases with chaperone activity, ATP-binding subunit; ATP-dependent transcriptional regulator, malt-like, luxr family protein 1388955 17441917 AFR_06320 Actinoplanes friuliensis DSM 7358 ATP-dependent transcriptional regulator, malt-like, luxr family protein YP_008732606.1 1386364 R 1246995 CDS YP_008732607.1 556564182 17441918 1389252..1389542 1 NC_022657.1 COG2127 Uncharacterized conserved protein; ATP-dependent Clp protease adaptor protein ClpS 1389542 clpS 17441918 clpS Actinoplanes friuliensis DSM 7358 ATP-dependent Clp protease adaptor protein ClpS YP_008732607.1 1389252 D 1246995 CDS YP_008732608.1 556564183 17441919 1389564..1390070 1 NC_022657.1 hypothetical protein 1390070 17441919 AFR_06330 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732608.1 1389564 D 1246995 CDS YP_008732609.1 556564184 17441920 complement(1390067..1390927) 1 NC_022657.1 COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases); aldo/keto reductase 1390927 17441920 AFR_06335 Actinoplanes friuliensis DSM 7358 aldo/keto reductase YP_008732609.1 1390067 R 1246995 CDS YP_008732610.1 556564185 17441921 1391016..1391438 1 NC_022657.1 COG1310 Predicted metal-dependent protease of the PAD1/JAB1 superfamily; Mov34/MPN/PAD-1 family protein 1391438 17441921 AFR_06340 Actinoplanes friuliensis DSM 7358 Mov34/MPN/PAD-1 family protein YP_008732610.1 1391016 D 1246995 CDS YP_008732611.1 556564186 17441922 1391583..1391942 1 NC_022657.1 COG1977 Molybdopterin converting factor, small subunit; putative sulfur transfer protein 1391942 17441922 AFR_06345 Actinoplanes friuliensis DSM 7358 putative sulfur transfer protein YP_008732611.1 1391583 D 1246995 CDS YP_008732612.1 556564187 17441923 1391946..1392911 1 NC_022657.1 COG0031 Cysteine synthase; cysteine synthase 1392911 17441923 AFR_06350 Actinoplanes friuliensis DSM 7358 cysteine synthase YP_008732612.1 1391946 D 1246995 CDS YP_008732613.1 556564188 17441924 complement(1392952..1393320) 1 NC_022657.1 hypothetical protein 1393320 17441924 AFR_06355 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732613.1 1392952 R 1246995 CDS YP_008732614.1 556564189 17441925 1393681..1394427 1 NC_022657.1 COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III; hypothetical protein 1394427 17441925 AFR_06360 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732614.1 1393681 D 1246995 CDS YP_008732615.1 556564190 17441926 1394498..1395739 1 NC_022657.1 COG0438 Glycosyltransferase; group 1 glycosyl transferase 1395739 17441926 AFR_06365 Actinoplanes friuliensis DSM 7358 group 1 glycosyl transferase YP_008732615.1 1394498 D 1246995 CDS YP_008732616.1 556564191 17441927 1395765..1396493 1 NC_022657.1 COG0689 RNase PH; ribonuclease PH 1396493 rph 17441927 rph Actinoplanes friuliensis DSM 7358 ribonuclease PH YP_008732616.1 1395765 D 1246995 CDS YP_008732617.1 556564192 17441928 1396490..1397104 1 NC_022657.1 COG0127 Xanthosine triphosphate pyrophosphatase; dITP/XTP pyrophosphatase 1397104 17441928 AFR_06375 Actinoplanes friuliensis DSM 7358 dITP/XTP pyrophosphatase YP_008732617.1 1396490 D 1246995 CDS YP_008732618.1 556564193 17441929 complement(1397114..1397911) 1 NC_022657.1 hypothetical protein 1397911 17441929 AFR_06380 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732618.1 1397114 R 1246995 CDS YP_008732619.1 556564194 17441930 complement(1397908..1398816) 1 NC_022657.1 COG1131 ABC-type multidrug transport system, ATPase component; ABC transporter-like protein 1398816 17441930 AFR_06385 Actinoplanes friuliensis DSM 7358 ABC transporter-like protein YP_008732619.1 1397908 R 1246995 CDS YP_008732620.1 556564195 17441931 complement(1398816..1399385) 1 NC_022657.1 regulatory protein ArsR 1399385 17441931 AFR_06390 Actinoplanes friuliensis DSM 7358 regulatory protein ArsR YP_008732620.1 1398816 R 1246995 CDS YP_008732621.1 556564196 17441932 1399467..1400699 1 NC_022657.1 hypothetical protein 1400699 17441932 AFR_06395 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732621.1 1399467 D 1246995 CDS YP_008732622.1 556564197 17441933 complement(1400696..1402705) 1 NC_022657.1 COG0457 FOG: TPR repeat; putative capsular polysaccharide synthesis protein 1402705 17441933 AFR_06400 Actinoplanes friuliensis DSM 7358 putative capsular polysaccharide synthesis protein YP_008732622.1 1400696 R 1246995 CDS YP_008732623.1 556564198 17441934 complement(1402762..1404285) 1 NC_022657.1 COG2986 Histidine ammonia-lyase; histidine ammonia-lyase 1404285 17441934 AFR_06405 Actinoplanes friuliensis DSM 7358 histidine ammonia-lyase YP_008732623.1 1402762 R 1246995 CDS YP_008732624.1 556564199 17441935 complement(1404294..1405442) 1 NC_022657.1 COG1228 Imidazolonepropionase and related amidohydrolases; imidazolonepropionase 1405442 17441935 AFR_06410 Actinoplanes friuliensis DSM 7358 imidazolonepropionase YP_008732624.1 1404294 R 1246995 CDS YP_008732625.1 556564200 17441936 complement(1405439..1406713) 1 NC_022657.1 COG0402 Cytosine deaminase and related metal-dependent hydrolases; N-formimino-L-glutamate deiminase 1406713 17441936 AFR_06415 Actinoplanes friuliensis DSM 7358 N-formimino-L-glutamate deiminase YP_008732625.1 1405439 R 1246995 CDS YP_008732626.1 556564201 17441937 complement(1406710..1407885) 1 NC_022657.1 COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases; allantoate amidohydrolase 1407885 17441937 AFR_06420 Actinoplanes friuliensis DSM 7358 allantoate amidohydrolase YP_008732626.1 1406710 R 1246995 CDS YP_008732627.1 556564202 17441938 complement(1407882..1409528) 1 NC_022657.1 COG2987 Urocanate hydratase; urocanate hydratase 1409528 17441938 AFR_06425 Actinoplanes friuliensis DSM 7358 urocanate hydratase YP_008732627.1 1407882 R 1246995 CDS YP_008732628.1 556564203 17441939 complement(1409541..1410356) 1 NC_022657.1 COG1737 Transcriptional regulators; putative RpiR-family transcriptional regulator 1410356 17441939 AFR_06430 Actinoplanes friuliensis DSM 7358 putative RpiR-family transcriptional regulator YP_008732628.1 1409541 R 1246995 CDS YP_008732629.1 556564204 17441940 1410505..1411308 1 NC_022657.1 COG3217 Uncharacterized Fe-S protein; hypothetical protein 1411308 17441940 AFR_06435 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732629.1 1410505 D 1246995 CDS YP_008732630.1 556564205 17441941 1411352..1412275 1 NC_022657.1 COG4305 Endoglucanase C-terminal domain/subunit and related proteins; hypothetical protein 1412275 17441941 AFR_06440 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732630.1 1411352 D 1246995 CDS YP_008732631.1 556564206 17441942 complement(1412283..1412801) 1 NC_022657.1 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; GCN5-like N-acetyltransferase 1412801 17441942 AFR_06445 Actinoplanes friuliensis DSM 7358 GCN5-like N-acetyltransferase YP_008732631.1 1412283 R 1246995 CDS YP_008732632.1 556564207 17441944 complement(1412988..1413878) 1 NC_022657.1 hypothetical protein 1413878 17441944 AFR_06450 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732632.1 1412988 R 1246995 CDS YP_008732633.1 556564208 17441945 complement(1413911..1414465) 1 NC_022657.1 COG1695 Predicted transcriptional regulators; Transcriptional regulator, PadR family protein 1414465 17441945 AFR_06455 Actinoplanes friuliensis DSM 7358 Transcriptional regulator, PadR family protein YP_008732633.1 1413911 R 1246995 CDS YP_008732634.1 556564209 17441946 1414536..1414910 1 NC_022657.1 hypothetical protein 1414910 17441946 AFR_06460 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732634.1 1414536 D 1246995 CDS YP_008732635.1 556564210 17441947 1414907..1415377 1 NC_022657.1 hypothetical protein 1415377 17441947 AFR_06465 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732635.1 1414907 D 1246995 CDS YP_008732636.1 556564211 17441948 complement(1415512..1417074) 1 NC_022657.1 COG0840 Methyl-accepting chemotaxis protein; methyl-accepting chemotaxis sensory transducer 1417074 17441948 AFR_06470 Actinoplanes friuliensis DSM 7358 methyl-accepting chemotaxis sensory transducer YP_008732636.1 1415512 R 1246995 CDS YP_008732637.1 556564212 17441949 complement(1417248..1417718) 1 NC_022657.1 COG1225 Peroxiredoxin; hypothetical protein 1417718 17441949 AFR_06475 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732637.1 1417248 R 1246995 CDS YP_008732638.1 556564213 17441950 complement(1417715..1418698) 1 NC_022657.1 hypothetical protein 1418698 17441950 AFR_06480 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732638.1 1417715 R 1246995 CDS YP_008732639.1 556564214 17441951 complement(1418695..1419426) 1 NC_022657.1 COG1651 Protein-disulfide isomerase; dsba oxidoreductase 1419426 17441951 AFR_06485 Actinoplanes friuliensis DSM 7358 dsba oxidoreductase YP_008732639.1 1418695 R 1246995 CDS YP_008732640.1 556564215 17441952 complement(1419423..1419914) 1 NC_022657.1 DoxX family protein 1419914 17441952 AFR_06490 Actinoplanes friuliensis DSM 7358 DoxX family protein YP_008732640.1 1419423 R 1246995 CDS YP_008732641.1 556564216 17441953 complement(1420005..1420544) 1 NC_022657.1 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; putative RNA polymerase ECF-subfamily sigma factor 1420544 17441953 AFR_06495 Actinoplanes friuliensis DSM 7358 putative RNA polymerase ECF-subfamily sigma factor YP_008732641.1 1420005 R 1246995 CDS YP_008732642.1 556564217 17441954 1420690..1422387 1 NC_022657.1 COG2372 Uncharacterized protein, homolog of Cu resistance protein CopC; hypothetical protein 1422387 17441954 AFR_06500 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732642.1 1420690 D 1246995 CDS YP_008732643.1 556564218 17441955 1422531..1427114 1 NC_022657.1 hypothetical protein 1427114 17441955 AFR_06505 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732643.1 1422531 D 1246995 CDS YP_008732644.1 556564219 17441956 1427422..1428012 1 NC_022657.1 COG1949 Oligoribonuclease (3'->5' exoribonuclease); oligoribonuclease 1428012 17441956 AFR_06510 Actinoplanes friuliensis DSM 7358 oligoribonuclease YP_008732644.1 1427422 D 1246995 CDS YP_008732645.1 556564220 17441958 complement(1430104..1431516) 1 NC_022657.1 COG0582 Integrase; LacI family transcriptional regulator 1431516 17441958 AFR_06515 Actinoplanes friuliensis DSM 7358 LacI family transcriptional regulator YP_008732645.1 1430104 R 1246995 CDS YP_008732646.1 556564221 17441959 complement(1432399..1433970) 1 NC_022657.1 hypothetical protein 1433970 17441959 AFR_06520 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732646.1 1432399 R 1246995 CDS YP_008732647.1 556564222 17441960 complement(1433967..1434911) 1 NC_022657.1 hypothetical protein 1434911 17441960 AFR_06525 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732647.1 1433967 R 1246995 CDS YP_008732648.1 556564223 17441961 complement(1434944..1435267) 1 NC_022657.1 hypothetical protein 1435267 17441961 AFR_06530 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732648.1 1434944 R 1246995 CDS YP_008732649.1 556564224 17441962 complement(1435267..1436865) 1 NC_022657.1 COG0270 Site-specific DNA methylase; C-5 cytosine-specific DNA methylase 1436865 17441962 AFR_06535 Actinoplanes friuliensis DSM 7358 C-5 cytosine-specific DNA methylase YP_008732649.1 1435267 R 1246995 CDS YP_008732650.1 556564225 17441963 complement(1436862..1437176) 1 NC_022657.1 hypothetical protein 1437176 17441963 AFR_06540 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732650.1 1436862 R 1246995 CDS YP_008732651.1 556564226 17441964 complement(1437203..1437529) 1 NC_022657.1 hypothetical protein 1437529 17441964 AFR_06545 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732651.1 1437203 R 1246995 CDS YP_008732652.1 556564227 17441965 complement(1437526..1437774) 1 NC_022657.1 hypothetical protein 1437774 17441965 AFR_06550 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732652.1 1437526 R 1246995 CDS YP_008732653.1 556564228 17441966 complement(1437927..1440119) 1 NC_022657.1 COG1674 DNA segregation ATPase FtsK/SpoIIIE and related proteins; cell division protein ftsk/spoiiie 1440119 17441966 AFR_06555 Actinoplanes friuliensis DSM 7358 cell division protein ftsk/spoiiie YP_008732653.1 1437927 R 1246995 CDS YP_008732654.1 556564229 17441967 complement(1440119..1440352) 1 NC_022657.1 hypothetical protein 1440352 17441967 AFR_06560 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732654.1 1440119 R 1246995 CDS YP_008732655.1 556564230 17441968 complement(1440349..1441122) 1 NC_022657.1 COG1051 ADP-ribose pyrophosphatase; hypothetical protein 1441122 17441968 AFR_06565 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732655.1 1440349 R 1246995 CDS YP_008732656.1 556564231 17441969 complement(1441223..1441432) 1 NC_022657.1 hypothetical protein 1441432 17441969 AFR_06570 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732656.1 1441223 R 1246995 CDS YP_008732657.1 556564232 17441970 complement(1441935..1442360) 1 NC_022657.1 hypothetical protein 1442360 17441970 AFR_06575 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732657.1 1441935 R 1246995 CDS YP_008732658.1 556564233 17441971 complement(1442460..1442651) 1 NC_022657.1 hypothetical protein 1442651 17441971 AFR_06580 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732658.1 1442460 R 1246995 CDS YP_008732659.1 556564234 17441972 complement(1443546..1444634) 1 NC_022657.1 hypothetical protein 1444634 17441972 AFR_06585 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732659.1 1443546 R 1246995 CDS YP_008732660.1 556564235 17441973 complement(1444783..1445046) 1 NC_022657.1 hypothetical protein 1445046 17441973 AFR_06590 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732660.1 1444783 R 1246995 CDS YP_008732661.1 556564236 17441974 complement(1447021..1447818) 1 NC_022657.1 COG2186 Transcriptional regulators; ADP-ribose pyrophosphatase 1447818 17441974 AFR_06595 Actinoplanes friuliensis DSM 7358 ADP-ribose pyrophosphatase YP_008732661.1 1447021 R 1246995 CDS YP_008732662.1 556564237 17441975 complement(1451992..1452276) 1 NC_022657.1 hypothetical protein 1452276 17441975 AFR_06600 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732662.1 1451992 R 1246995 CDS YP_008732663.1 556564238 17441976 complement(1452273..1452578) 1 NC_022657.1 hypothetical protein 1452578 17441976 AFR_06605 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732663.1 1452273 R 1246995 CDS YP_008732664.1 556564239 17441977 complement(1452598..1453692) 1 NC_022657.1 hypothetical protein 1453692 17441977 AFR_06610 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732664.1 1452598 R 1246995 CDS YP_008732665.1 556564240 17441978 complement(1454852..1455793) 1 NC_022657.1 COG3300 MHYT domain (predicted integral membrane sensor domain); integral membrane sensor protein 1455793 17441978 AFR_06615 Actinoplanes friuliensis DSM 7358 integral membrane sensor protein YP_008732665.1 1454852 R 1246995 CDS YP_008732666.1 556564241 17441979 complement(1455882..1458923) 1 NC_022657.1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; SARP family transcriptional regulator 1458923 17441979 AFR_06620 Actinoplanes friuliensis DSM 7358 SARP family transcriptional regulator YP_008732666.1 1455882 R 1246995 CDS YP_008732667.1 556564242 17441980 complement(1458933..1459670) 1 NC_022657.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); hypothetical protein 1459670 17441980 AFR_06625 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732667.1 1458933 R 1246995 CDS YP_008732668.1 556564243 17441981 complement(1459729..1460517) 1 NC_022657.1 COG1752 Predicted esterase of the alpha-beta hydrolase superfamily; putative patatin-like phospholipase 1460517 17441981 AFR_06630 Actinoplanes friuliensis DSM 7358 putative patatin-like phospholipase YP_008732668.1 1459729 R 1246995 CDS YP_008732669.1 556564244 17441982 complement(1460589..1461980) 1 NC_022657.1 COG0665 Glycine/D-amino acid oxidases (deaminating); Gamma-glutamylputrescine oxidoreductase 1461980 17441982 AFR_06635 Actinoplanes friuliensis DSM 7358 Gamma-glutamylputrescine oxidoreductase YP_008732669.1 1460589 R 1246995 CDS YP_008732670.1 556564245 17441983 complement(1461983..1462816) 1 NC_022657.1 COG1177 ABC-type spermidine/putrescine transport system, permease component II; ABC transporter permease 1462816 17441983 AFR_06640 Actinoplanes friuliensis DSM 7358 ABC transporter permease YP_008732670.1 1461983 R 1246995 CDS YP_008732671.1 556564246 17441984 complement(1462813..1463676) 1 NC_022657.1 COG1176 ABC-type spermidine/putrescine transport system, permease component I; ABC transporter permease 1463676 17441984 AFR_06645 Actinoplanes friuliensis DSM 7358 ABC transporter permease YP_008732671.1 1462813 R 1246995 CDS YP_008732672.1 556564247 17441985 complement(1463682..1464935) 1 NC_022657.1 COG0687 Spermidine/putrescine-binding periplasmic protein; Spermidine/putrescine-binding periplasmic protein 2 1464935 17441985 AFR_06650 Actinoplanes friuliensis DSM 7358 Spermidine/putrescine-binding periplasmic protein 2 YP_008732672.1 1463682 R 1246995 CDS YP_008732673.1 556564248 17441986 complement(1464935..1466068) 1 NC_022657.1 COG3842 ABC-type spermidine/putrescine transport systems, ATPase components; spermidine/putrescine ABC transporter ATPase 1466068 17441986 AFR_06655 Actinoplanes friuliensis DSM 7358 spermidine/putrescine ABC transporter ATPase YP_008732673.1 1464935 R 1246995 CDS YP_008732674.1 556564249 17441987 complement(1466104..1467540) 1 NC_022657.1 COG1012 NAD-dependent aldehyde dehydrogenases; betaine aldehyde dehydrogenase 1467540 17441987 AFR_06660 Actinoplanes friuliensis DSM 7358 betaine aldehyde dehydrogenase YP_008732674.1 1466104 R 1246995 CDS YP_008732675.1 556564250 17441988 1468877..1469926 1 NC_022657.1 hypothetical protein 1469926 17441988 AFR_06665 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732675.1 1468877 D 1246995 CDS YP_008732676.1 556564251 17441989 1469947..1471143 1 NC_022657.1 COG0714 MoxR-like ATPases; hypothetical protein 1471143 17441989 AFR_06670 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732676.1 1469947 D 1246995 CDS YP_008732677.1 556564252 17441990 1471140..1472366 1 NC_022657.1 COG3864 Uncharacterized protein conserved in bacteria; hypothetical protein 1472366 17441990 AFR_06675 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732677.1 1471140 D 1246995 CDS YP_008732678.1 556564253 17441991 complement(1472389..1473582) 1 NC_022657.1 COG0525 Valyl-tRNA synthetase; hypothetical protein 1473582 17441991 AFR_06680 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732678.1 1472389 R 1246995 CDS YP_008732679.1 556564254 17441992 complement(1473683..1475398) 1 NC_022657.1 COG3391 Uncharacterized conserved protein; hypothetical protein 1475398 17441992 AFR_06685 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732679.1 1473683 R 1246995 CDS YP_008732680.1 556564255 17441993 1475546..1476067 1 NC_022657.1 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; RNA polymerase sigma factor sigX 1476067 17441993 AFR_06690 Actinoplanes friuliensis DSM 7358 RNA polymerase sigma factor sigX YP_008732680.1 1475546 D 1246995 CDS YP_008732681.1 556564256 17441994 1476060..1477343 1 NC_022657.1 hypothetical protein 1477343 17441994 AFR_06695 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732681.1 1476060 D 1246995 CDS YP_008732682.1 556564257 17441995 1477340..1477837 1 NC_022657.1 hypothetical protein 1477837 17441995 AFR_06700 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732682.1 1477340 D 1246995 CDS YP_008732683.1 556564258 17441996 complement(1477827..1478114) 1 NC_022657.1 hypothetical protein 1478114 17441996 AFR_06705 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732683.1 1477827 R 1246995 CDS YP_008732684.1 556564259 17441997 complement(1478133..1478777) 1 NC_022657.1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; Two component response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain 1478777 17441997 AFR_06710 Actinoplanes friuliensis DSM 7358 Two component response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain YP_008732684.1 1478133 R 1246995 CDS YP_008732685.1 556564260 17441998 complement(1478774..1479997) 1 NC_022657.1 COG4585 Signal transduction histidine kinase; Two component signal transduction histidine kinase 1479997 17441998 AFR_06715 Actinoplanes friuliensis DSM 7358 Two component signal transduction histidine kinase YP_008732685.1 1478774 R 1246995 CDS YP_008732686.1 556564261 17441999 complement(1479987..1480364) 1 NC_022657.1 hypothetical protein 1480364 17441999 AFR_06720 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732686.1 1479987 R 1246995 CDS YP_008732687.1 556564262 17442000 complement(1480434..1481075) 1 NC_022657.1 COG1136 ABC-type antimicrobial peptide transport system, ATPase component; acetoin ABC transporter ATP-binding protein YtrE 1481075 17442000 AFR_06725 Actinoplanes friuliensis DSM 7358 acetoin ABC transporter ATP-binding protein YtrE YP_008732687.1 1480434 R 1246995 CDS YP_008732688.1 556564263 17442001 complement(1481072..1481899) 1 NC_022657.1 COG1136 ABC-type antimicrobial peptide transport system, ATPase component; ABC transporter 1481899 17442001 AFR_06730 Actinoplanes friuliensis DSM 7358 ABC transporter YP_008732688.1 1481072 R 1246995 CDS YP_008732689.1 556564264 17442002 complement(1481889..1484675) 1 NC_022657.1 hypothetical protein 1484675 17442002 AFR_06735 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732689.1 1481889 R 1246995 CDS YP_008732690.1 556564265 17442003 1484768..1485607 1 NC_022657.1 COG0789 Predicted transcriptional regulators; regulatory protein MerR 1485607 17442003 AFR_06740 Actinoplanes friuliensis DSM 7358 regulatory protein MerR YP_008732690.1 1484768 D 1246995 CDS YP_008732691.1 556564266 17442004 complement(1485594..1488071) 1 NC_022657.1 COG1404 Subtilisin-like serine proteases; putative subtilase-family protease 1488071 17442004 AFR_06745 Actinoplanes friuliensis DSM 7358 putative subtilase-family protease YP_008732691.1 1485594 R 1246995 CDS YP_008732692.1 556564267 17442006 1488449..1489726 1 NC_022657.1 COG1376 Uncharacterized protein conserved in bacteria; hypothetical protein 1489726 17442006 AFR_06750 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732692.1 1488449 D 1246995 CDS YP_008732693.1 556564268 17442007 1489885..1491117 1 NC_022657.1 COG1376 Uncharacterized protein conserved in bacteria; hypothetical protein 1491117 17442007 AFR_06755 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732693.1 1489885 D 1246995 CDS YP_008732694.1 556564269 17442008 1491237..1491617 1 NC_022657.1 hypothetical protein 1491617 17442008 AFR_06760 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732694.1 1491237 D 1246995 CDS YP_008732695.1 556564270 17442009 1492396..1493073 1 NC_022657.1 COG3217 Uncharacterized Fe-S protein; MOSC domain-containing protein 1493073 17442009 AFR_06765 Actinoplanes friuliensis DSM 7358 MOSC domain-containing protein YP_008732695.1 1492396 D 1246995 CDS YP_008732696.1 556564271 17442010 complement(1493081..1495828) 1 NC_022657.1 COG0457 FOG: TPR repeat; SARP family transcriptional regulator 1495828 17442010 AFR_06770 Actinoplanes friuliensis DSM 7358 SARP family transcriptional regulator YP_008732696.1 1493081 R 1246995 CDS YP_008732697.1 556564272 17442011 complement(1495987..1496331) 1 NC_022657.1 hypothetical protein 1496331 17442011 AFR_06775 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732697.1 1495987 R 1246995 CDS YP_008732698.1 556564273 17442012 complement(1496373..1496804) 1 NC_022657.1 COG0784 FOG: CheY-like receiver; putative response regulator receiver domain protein 1496804 17442012 AFR_06780 Actinoplanes friuliensis DSM 7358 putative response regulator receiver domain protein YP_008732698.1 1496373 R 1246995 CDS YP_008732699.1 556564274 17442013 complement(1496871..1497794) 1 NC_022657.1 COG2064 Flp pilus assembly protein TadC; type II secretion system protein 1497794 17442013 AFR_06785 Actinoplanes friuliensis DSM 7358 type II secretion system protein YP_008732699.1 1496871 R 1246995 CDS YP_008732700.1 556564275 17442014 complement(1497796..1498743) 1 NC_022657.1 COG4965 Flp pilus assembly protein TadB; type II secretion system protein 1498743 17442014 AFR_06790 Actinoplanes friuliensis DSM 7358 type II secretion system protein YP_008732700.1 1497796 R 1246995 CDS YP_008732701.1 556564276 17442015 complement(1498740..1500137) 1 NC_022657.1 COG4962 Flp pilus assembly protein, ATPase CpaF; type II secretion system protein E 1500137 17442015 AFR_06795 Actinoplanes friuliensis DSM 7358 type II secretion system protein E YP_008732701.1 1498740 R 1246995 CDS YP_008732702.1 556564277 17442016 complement(1500134..1501309) 1 NC_022657.1 COG4963 Flp pilus assembly protein, ATPase CpaE; AAA ATPase 1501309 17442016 AFR_06800 Actinoplanes friuliensis DSM 7358 AAA ATPase YP_008732702.1 1500134 R 1246995 CDS YP_008732703.1 556564278 17442017 complement(1501320..1502063) 1 NC_022657.1 Flp pilus assembly protein CpaB 1502063 17442017 AFR_06805 Actinoplanes friuliensis DSM 7358 Flp pilus assembly protein CpaB YP_008732703.1 1501320 R 1246995 CDS YP_008732704.1 556564279 17442018 complement(1502089..1503207) 1 NC_022657.1 hypothetical protein 1503207 17442018 AFR_06810 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732704.1 1502089 R 1246995 CDS YP_008732705.1 556564280 17442019 complement(1503195..1503506) 1 NC_022657.1 hypothetical protein 1503506 17442019 AFR_06815 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732705.1 1503195 R 1246995 CDS YP_008732706.1 556564281 17442020 complement(1503608..1503802) 1 NC_022657.1 membrane protein 1503802 17442020 AFR_06820 Actinoplanes friuliensis DSM 7358 membrane protein YP_008732706.1 1503608 R 1246995 CDS YP_008732707.1 556564282 17442021 complement(1503953..1504180) 1 NC_022657.1 COG1161 Predicted GTPases; hypothetical protein 1504180 17442021 AFR_06825 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732707.1 1503953 R 1246995 CDS YP_008732708.1 556564283 17442022 complement(1504378..1504851) 1 NC_022657.1 hypothetical protein 1504851 17442022 AFR_06830 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732708.1 1504378 R 1246995 CDS YP_008732709.1 556564284 17442023 1504920..1505387 1 NC_022657.1 COG1522 Transcriptional regulators; AsnC family transcriptional regulator 1505387 17442023 AFR_06835 Actinoplanes friuliensis DSM 7358 AsnC family transcriptional regulator YP_008732709.1 1504920 D 1246995 CDS YP_008732710.1 556564285 17442024 complement(1505371..1505991) 1 NC_022657.1 COG3647 Predicted membrane protein; hypothetical protein 1505991 17442024 AFR_06840 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732710.1 1505371 R 1246995 CDS YP_008732711.1 556564286 17442025 1506065..1506550 1 NC_022657.1 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; GCN5-like N-acetyltransferase 1506550 17442025 AFR_06845 Actinoplanes friuliensis DSM 7358 GCN5-like N-acetyltransferase YP_008732711.1 1506065 D 1246995 CDS YP_008732712.1 556564287 17442026 1506665..1507525 1 NC_022657.1 COG0092 Ribosomal protein S3; hypothetical protein 1507525 17442026 AFR_06850 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732712.1 1506665 D 1246995 CDS YP_008732713.1 556564288 17442027 1507718..1508155 1 NC_022657.1 hypothetical protein 1508155 17442027 AFR_06855 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732713.1 1507718 D 1246995 CDS YP_008732714.1 556564289 17442028 complement(1508195..1510780) 1 NC_022657.1 hypothetical protein 1510780 17442028 AFR_06860 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732714.1 1508195 R 1246995 CDS YP_008732715.1 556564290 17442029 complement(1510910..1511416) 1 NC_022657.1 COG2320 Uncharacterized conserved protein; hypothetical protein 1511416 17442029 AFR_06865 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732715.1 1510910 R 1246995 CDS YP_008732716.1 556564291 17442030 complement(1511413..1512297) 1 NC_022657.1 COG0598 Mg2+ and Co2+ transporters; putative metal ion transport protein 1512297 17442030 AFR_06870 Actinoplanes friuliensis DSM 7358 putative metal ion transport protein YP_008732716.1 1511413 R 1246995 CDS YP_008732717.1 556564292 17442031 complement(1512658..1513395) 1 NC_022657.1 COG0842 ABC-type multidrug transport system, permease component; ABC transporter permease 1513395 17442031 AFR_06875 Actinoplanes friuliensis DSM 7358 ABC transporter permease YP_008732717.1 1512658 R 1246995 CDS YP_008732718.1 556564293 17442032 complement(1513399..1514370) 1 NC_022657.1 COG1131 ABC-type multidrug transport system, ATPase component; putative ABC transporter ATP-binding protein 1514370 17442032 AFR_06880 Actinoplanes friuliensis DSM 7358 putative ABC transporter ATP-binding protein YP_008732718.1 1513399 R 1246995 CDS YP_008732719.1 556564294 17442033 1514433..1515389 1 NC_022657.1 COG2378 Predicted transcriptional regulator; DeoR family transcriptional regulator 1515389 17442033 AFR_06885 Actinoplanes friuliensis DSM 7358 DeoR family transcriptional regulator YP_008732719.1 1514433 D 1246995 CDS YP_008732720.1 556564295 17442034 1515585..1516628 1 NC_022657.1 COG1228 Imidazolonepropionase and related amidohydrolases; amidohydrolase 1516628 17442034 AFR_06890 Actinoplanes friuliensis DSM 7358 amidohydrolase YP_008732720.1 1515585 D 1246995 CDS YP_008732721.1 556564296 17442035 1516670..1517224 1 NC_022657.1 COG3236 Uncharacterized protein conserved in bacteria; hypothetical protein 1517224 17442035 AFR_06895 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732721.1 1516670 D 1246995 CDS YP_008732722.1 556564297 17442036 complement(1517848..1518663) 1 NC_022657.1 COG0642 Signal transduction histidine kinase; hypothetical protein 1518663 17442036 AFR_06900 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732722.1 1517848 R 1246995 CDS YP_008732723.1 556564298 17442037 1518812..1519555 1 NC_022657.1 COG0640 Predicted transcriptional regulators; ArsR family transcriptional regulator 1519555 17442037 AFR_06905 Actinoplanes friuliensis DSM 7358 ArsR family transcriptional regulator YP_008732723.1 1518812 D 1246995 CDS YP_008732724.1 556564299 17442038 1519552..1520394 1 NC_022657.1 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases; FMNH2-utilizing oxygenase 1520394 17442038 AFR_06910 Actinoplanes friuliensis DSM 7358 FMNH2-utilizing oxygenase YP_008732724.1 1519552 D 1246995 CDS YP_008732725.1 556564300 17442039 1520448..1520936 1 NC_022657.1 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; NUDIX hydrolase 1520936 17442039 AFR_06915 Actinoplanes friuliensis DSM 7358 NUDIX hydrolase YP_008732725.1 1520448 D 1246995 CDS YP_008732726.1 556564301 17442040 complement(1521105..1521644) 1 NC_022657.1 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; N-acetyltransferase GCN5 1521644 17442040 AFR_06920 Actinoplanes friuliensis DSM 7358 N-acetyltransferase GCN5 YP_008732726.1 1521105 R 1246995 CDS YP_008732727.1 556564302 17442041 1521756..1523252 1 NC_022657.1 COG3525 N-acetyl-beta-hexosaminidase; putative beta-N-acetylhexosaminidase 1523252 17442041 AFR_06925 Actinoplanes friuliensis DSM 7358 putative beta-N-acetylhexosaminidase YP_008732727.1 1521756 D 1246995 CDS YP_008732728.1 556564303 17442042 complement(1523381..1523593) 1 NC_022657.1 hypothetical protein 1523593 17442042 AFR_06930 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732728.1 1523381 R 1246995 CDS YP_008732729.1 556564304 17442043 1523647..1525911 1 NC_022657.1 hypothetical protein 1525911 17442043 AFR_06935 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732729.1 1523647 D 1246995 CDS YP_008732730.1 556564305 17442044 1526111..1526605 1 NC_022657.1 hypothetical protein 1526605 17442044 AFR_06940 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732730.1 1526111 D 1246995 CDS YP_008732731.1 556564306 17442045 complement(1526612..1527031) 1 NC_022657.1 hypothetical protein 1527031 17442045 AFR_06945 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732731.1 1526612 R 1246995 CDS YP_008732732.1 556564307 17442046 complement(1527036..1528025) 1 NC_022657.1 COG2378 Predicted transcriptional regulator; helix-turn-helix type 11 domain-containing protein 1528025 17442046 AFR_06950 Actinoplanes friuliensis DSM 7358 helix-turn-helix type 11 domain-containing protein YP_008732732.1 1527036 R 1246995 CDS YP_008732733.1 556564308 17442047 complement(1528087..1529079) 1 NC_022657.1 hypothetical protein 1529079 17442047 AFR_06955 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732733.1 1528087 R 1246995 CDS YP_008732734.1 556564309 17442048 complement(1529091..1529735) 1 NC_022657.1 hypothetical protein 1529735 17442048 AFR_06960 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732734.1 1529091 R 1246995 CDS YP_008732735.1 556564310 17442049 1530065..1533028 1 NC_022657.1 COG0642 Signal transduction histidine kinase; putative sensor-like histidine kinase 1533028 17442049 AFR_06965 Actinoplanes friuliensis DSM 7358 putative sensor-like histidine kinase YP_008732735.1 1530065 D 1246995 CDS YP_008732736.1 556564311 17442050 1533029..1533445 1 NC_022657.1 COG2018 Uncharacterized distant relative of homeotic protein bithoraxoid; roadblock/LC7 family protein 1533445 17442050 AFR_06970 Actinoplanes friuliensis DSM 7358 roadblock/LC7 family protein YP_008732736.1 1533029 D 1246995 CDS YP_008732737.1 556564312 17442051 1533435..1533821 1 NC_022657.1 hypothetical protein 1533821 17442051 AFR_06975 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732737.1 1533435 D 1246995 CDS YP_008732738.1 556564313 17442052 1533802..1534401 1 NC_022657.1 COG2229 Predicted GTPase; putative ATP/GTP-binding protein 1534401 17442052 AFR_06980 Actinoplanes friuliensis DSM 7358 putative ATP/GTP-binding protein YP_008732738.1 1533802 D 1246995 CDS YP_008732739.1 556564314 17442053 complement(1534405..1536102) 1 NC_022657.1 COG3629 DNA-binding transcriptional activator of the SARP family; transcriptional activator domain-containing protein 1536102 17442053 AFR_06985 Actinoplanes friuliensis DSM 7358 transcriptional activator domain-containing protein YP_008732739.1 1534405 R 1246995 CDS YP_008732740.1 556564315 17442054 1536263..1537060 1 NC_022657.1 hypothetical protein 1537060 17442054 AFR_06990 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732740.1 1536263 D 1246995 CDS YP_008732741.1 556564316 17442055 1537141..1538199 1 NC_022657.1 COG2706 3-carboxymuconate cyclase; hypothetical protein 1538199 17442055 AFR_06995 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732741.1 1537141 D 1246995 CDS YP_008732742.1 556564317 17442056 1538447..1540147 1 NC_022657.1 COG2304 Uncharacterized protein containing a von Willebrand factor type A (vWA) domain; hypothetical protein 1540147 17442056 AFR_07000 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732742.1 1538447 D 1246995 CDS YP_008732743.1 556564318 17442057 complement(1540202..1541335) 1 NC_022657.1 COG2208 Serine phosphatase RsbU, regulator of sigma subunit; stage II sporulation protein E 1541335 17442057 AFR_07005 Actinoplanes friuliensis DSM 7358 stage II sporulation protein E YP_008732743.1 1540202 R 1246995 CDS YP_008732744.1 556564319 17442058 1541387..1541869 1 NC_022657.1 COG1846 Transcriptional regulators; regulatory protein marr 1541869 17442058 AFR_07010 Actinoplanes friuliensis DSM 7358 regulatory protein marr YP_008732744.1 1541387 D 1246995 CDS YP_008732745.1 556564320 17442059 complement(1541874..1542890) 1 NC_022657.1 COG1940 Transcriptional regulator/sugar kinase; rok family protein 1542890 17442059 AFR_07015 Actinoplanes friuliensis DSM 7358 rok family protein YP_008732745.1 1541874 R 1246995 CDS YP_008732746.1 556564321 17442060 1543132..1544319 1 NC_022657.1 COG2115 Xylose isomerase; xylose isomerase 1544319 17442060 AFR_07020 Actinoplanes friuliensis DSM 7358 xylose isomerase YP_008732746.1 1543132 D 1246995 CDS YP_008732747.1 556564322 17442061 1544342..1545757 1 NC_022657.1 COG1070 Sugar (pentulose and hexulose) kinases; putative xylulokinase 1545757 17442061 AFR_07025 Actinoplanes friuliensis DSM 7358 putative xylulokinase YP_008732747.1 1544342 D 1246995 CDS YP_008732748.1 556564323 17442062 1545807..1547177 1 NC_022657.1 COG0477 Permeases of the major facilitator superfamily; putative MFS transporter 1547177 17442062 AFR_07030 Actinoplanes friuliensis DSM 7358 putative MFS transporter YP_008732748.1 1545807 D 1246995 CDS YP_008732749.1 556564324 17442063 complement(1547155..1548786) 1 NC_022657.1 COG0366 Glycosidases; putative glycosyl hydrolase 1548786 17442063 AFR_07035 Actinoplanes friuliensis DSM 7358 putative glycosyl hydrolase YP_008732749.1 1547155 R 1246995 CDS YP_008732750.1 556564325 17442064 complement(1548806..1549501) 1 NC_022657.1 COG0317 Guanosine polyphosphate pyrophosphohydrolases/synthetases; GTP pyrophosphokinase 1549501 17442064 AFR_07040 Actinoplanes friuliensis DSM 7358 GTP pyrophosphokinase YP_008732750.1 1548806 R 1246995 CDS YP_008732751.1 556564326 17442065 complement(1549569..1550492) 1 NC_022657.1 COG3300 MHYT domain (predicted integral membrane sensor domain); hypothetical protein 1550492 17442065 AFR_07045 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732751.1 1549569 R 1246995 CDS YP_008732752.1 556564327 17442066 complement(1550697..1550843) 1 NC_022657.1 hypothetical protein 1550843 17442066 AFR_07050 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732752.1 1550697 R 1246995 CDS YP_008732753.1 556564328 17442067 complement(1550976..1551719) 1 NC_022657.1 COG2129 Predicted phosphoesterases, related to the Icc protein; putative metallophosphoesterase 1551719 17442067 AFR_07055 Actinoplanes friuliensis DSM 7358 putative metallophosphoesterase YP_008732753.1 1550976 R 1246995 CDS YP_008732754.1 556564329 17442068 complement(1551716..1551970) 1 NC_022657.1 hypothetical protein 1551970 17442068 AFR_07060 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732754.1 1551716 R 1246995 CDS YP_008732755.1 556564330 17442069 complement(1551972..1552556) 1 NC_022657.1 hypothetical protein 1552556 17442069 AFR_07065 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732755.1 1551972 R 1246995 CDS YP_008732756.1 556564331 17442070 1552722..1553516 1 NC_022657.1 COG0125 Thymidylate kinase; thymidylate kinase 1553516 17442070 AFR_07070 Actinoplanes friuliensis DSM 7358 thymidylate kinase YP_008732756.1 1552722 D 1246995 CDS YP_008732757.1 556564332 17442071 complement(1553513..1554205) 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); putative short-chain dehydrogenase 1554205 17442071 AFR_07075 Actinoplanes friuliensis DSM 7358 putative short-chain dehydrogenase YP_008732757.1 1553513 R 1246995 CDS YP_008732758.1 556564333 17442072 1554801..1555751 1 NC_022657.1 COG0568 DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32); RNA polymerase principal sigma factor hrdB 1555751 17442072 AFR_07080 Actinoplanes friuliensis DSM 7358 RNA polymerase principal sigma factor hrdB YP_008732758.1 1554801 D 1246995 CDS YP_008732759.1 556564334 17442073 complement(1555825..1556748) 1 NC_022657.1 COG0791 Cell wall-associated hydrolases (invasion-associated proteins); hypothetical protein 1556748 17442073 AFR_07085 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732759.1 1555825 R 1246995 CDS YP_008732760.1 556564335 17442074 complement(1557141..1557467) 1 NC_022657.1 hypothetical protein 1557467 17442074 AFR_07090 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732760.1 1557141 R 1246995 CDS YP_008732761.1 556564336 17442075 complement(1557485..1557904) 1 NC_022657.1 COG4578 Glucitol operon activator; hypothetical protein 1557904 17442075 AFR_07095 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732761.1 1557485 R 1246995 CDS YP_008732762.1 556564337 17442076 1557995..1558252 1 NC_022657.1 hypothetical protein 1558252 17442076 AFR_07100 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732762.1 1557995 D 1246995 CDS YP_008732763.1 556564338 17442077 1558273..1558833 1 NC_022657.1 hypothetical protein 1558833 17442077 AFR_07105 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732763.1 1558273 D 1246995 CDS YP_008732764.1 556564339 17442078 complement(1558883..1559068) 1 NC_022657.1 hypothetical protein 1559068 17442078 AFR_07110 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732764.1 1558883 R 1246995 CDS YP_008732765.1 556564340 17442079 complement(1559095..1559295) 1 NC_022657.1 hypothetical protein 1559295 17442079 AFR_07115 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732765.1 1559095 R 1246995 CDS YP_008732766.1 556564341 17442080 1559573..1559776 1 NC_022657.1 hypothetical protein 1559776 17442080 AFR_07120 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732766.1 1559573 D 1246995 CDS YP_008732767.1 556564342 17442081 1559776..1560861 1 NC_022657.1 COG2203 FOG: GAF domain; hypothetical protein 1560861 17442081 AFR_07125 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732767.1 1559776 D 1246995 CDS YP_008732768.1 556564343 17442082 complement(1560865..1561167) 1 NC_022657.1 COG2329 Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides; putative monooxygenase 1561167 17442082 AFR_07130 Actinoplanes friuliensis DSM 7358 putative monooxygenase YP_008732768.1 1560865 R 1246995 CDS YP_008732769.1 556564344 17442083 complement(1561224..1562960) 1 NC_022657.1 COG0477 Permeases of the major facilitator superfamily; EmrB/QacA subfamily drug resistance transporter 1562960 17442083 AFR_07135 Actinoplanes friuliensis DSM 7358 EmrB/QacA subfamily drug resistance transporter YP_008732769.1 1561224 R 1246995 CDS YP_008732770.1 556564345 17442084 complement(1562957..1563442) 1 NC_022657.1 COG1846 Transcriptional regulators; putative MarR-family transcriptional regulator 1563442 17442084 AFR_07140 Actinoplanes friuliensis DSM 7358 putative MarR-family transcriptional regulator YP_008732770.1 1562957 R 1246995 CDS YP_008732771.1 556564346 17442085 complement(1563511..1564140) 1 NC_022657.1 putative methyltransferase 1564140 17442085 AFR_07145 Actinoplanes friuliensis DSM 7358 putative methyltransferase YP_008732771.1 1563511 R 1246995 CDS YP_008732772.1 556564347 17442086 complement(1564210..1564857) 1 NC_022657.1 hypothetical protein 1564857 17442086 AFR_07150 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732772.1 1564210 R 1246995 CDS YP_008732773.1 556564348 17442087 1565098..1565760 1 NC_022657.1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; putative two-component system response regulator 1565760 17442087 AFR_07155 Actinoplanes friuliensis DSM 7358 putative two-component system response regulator YP_008732773.1 1565098 D 1246995 CDS YP_008732774.1 556564349 17442088 1565900..1567387 1 NC_022657.1 hypothetical protein 1567387 17442088 AFR_07160 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732774.1 1565900 D 1246995 CDS YP_008732775.1 556564350 17442089 complement(1567409..1568620) 1 NC_022657.1 COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases; D-3-phosphoglycerate dehydrogenase 1568620 17442089 AFR_07165 Actinoplanes friuliensis DSM 7358 D-3-phosphoglycerate dehydrogenase YP_008732775.1 1567409 R 1246995 CDS YP_008732776.1 556564351 17442090 complement(1568748..1569665) 1 NC_022657.1 COG0515 Serine/threonine protein kinase; putative phosphotransferase 1569665 17442090 AFR_07170 Actinoplanes friuliensis DSM 7358 putative phosphotransferase YP_008732776.1 1568748 R 1246995 CDS YP_008732777.1 556564352 17442091 1569851..1570819 1 NC_022657.1 COG1131 ABC-type multidrug transport system, ATPase component; ABC transporter ATP-binding protein 1570819 17442091 AFR_07175 Actinoplanes friuliensis DSM 7358 ABC transporter ATP-binding protein YP_008732777.1 1569851 D 1246995 CDS YP_008732778.1 556564353 17442092 1570816..1571652 1 NC_022657.1 COG0842 ABC-type multidrug transport system, permease component; ABC transporter 1571652 17442092 AFR_07180 Actinoplanes friuliensis DSM 7358 ABC transporter YP_008732778.1 1570816 D 1246995 CDS YP_008732779.1 556564354 17442093 complement(1572843..1573289) 1 NC_022657.1 COG1846 Transcriptional regulators; transcriptional regulator TrmB 1573289 17442093 AFR_07185 Actinoplanes friuliensis DSM 7358 transcriptional regulator TrmB YP_008732779.1 1572843 R 1246995 CDS YP_008732780.1 556564355 17442094 1573367..1574575 1 NC_022657.1 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases; monooxygenase FAD-binding protein 1574575 17442094 AFR_07190 Actinoplanes friuliensis DSM 7358 monooxygenase FAD-binding protein YP_008732780.1 1573367 D 1246995 CDS YP_008732781.1 556564356 17442095 1574695..1575675 1 NC_022657.1 hypothetical protein 1575675 17442095 AFR_07195 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732781.1 1574695 D 1246995 CDS YP_008732782.1 556564357 17442096 1575729..1576424 1 NC_022657.1 COG4340 Uncharacterized protein conserved in bacteria; hypothetical protein 1576424 17442096 AFR_07200 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732782.1 1575729 D 1246995 CDS YP_008732783.1 556564358 17442097 complement(1576409..1577521) 1 NC_022657.1 COG0642 Signal transduction histidine kinase; integral membrane sensor signal transduction histidine kinase 1577521 17442097 AFR_07205 Actinoplanes friuliensis DSM 7358 integral membrane sensor signal transduction histidine kinase YP_008732783.1 1576409 R 1246995 CDS YP_008732784.1 556564359 17442098 complement(1577518..1578174) 1 NC_022657.1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; two component transcriptional regulator 1578174 17442098 AFR_07210 Actinoplanes friuliensis DSM 7358 two component transcriptional regulator YP_008732784.1 1577518 R 1246995 CDS YP_008732785.1 556564360 17442099 1578299..1578847 1 NC_022657.1 hypothetical protein 1578847 17442099 AFR_07215 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732785.1 1578299 D 1246995 CDS YP_008732786.1 556564361 17442100 1578844..1579884 1 NC_022657.1 COG3409 Putative peptidoglycan-binding domain-containing protein; peptidoglycan-binding domain 1 protein 1579884 17442100 AFR_07220 Actinoplanes friuliensis DSM 7358 peptidoglycan-binding domain 1 protein YP_008732786.1 1578844 D 1246995 CDS YP_008732787.1 556564362 17442101 1579881..1580540 1 NC_022657.1 COG1136 ABC-type antimicrobial peptide transport system, ATPase component; hypothetical protein 1580540 17442101 AFR_07225 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732787.1 1579881 D 1246995 CDS YP_008732788.1 556564363 17442102 1580542..1581720 1 NC_022657.1 COG0577 ABC-type antimicrobial peptide transport system, permease component; ABC transporter 1581720 17442102 AFR_07230 Actinoplanes friuliensis DSM 7358 ABC transporter YP_008732788.1 1580542 D 1246995 CDS YP_008732789.1 556564364 17442103 1581725..1581961 1 NC_022657.1 hypothetical protein 1581961 17442103 AFR_07235 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732789.1 1581725 D 1246995 CDS YP_008732790.1 556564365 17442104 1582082..1582417 1 NC_022657.1 COG3795 Uncharacterized protein conserved in bacteria; hypothetical protein 1582417 17442104 AFR_07240 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732790.1 1582082 D 1246995 CDS YP_008732791.1 556564366 17442105 1582562..1583278 1 NC_022657.1 COG4941 Predicted RNA polymerase sigma factor containing a TPR repeat domain; ECF subfamily RNA polymerase sigma-24 subunit 1583278 17442105 AFR_07245 Actinoplanes friuliensis DSM 7358 ECF subfamily RNA polymerase sigma-24 subunit YP_008732791.1 1582562 D 1246995 CDS YP_008732792.1 556564367 17442106 complement(1583268..1584137) 1 NC_022657.1 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; ECF subfamily RNA polymerase sigma factor 1584137 17442106 AFR_07250 Actinoplanes friuliensis DSM 7358 ECF subfamily RNA polymerase sigma factor YP_008732792.1 1583268 R 1246995 CDS YP_008732793.1 556564368 17442107 complement(1584134..1584715) 1 NC_022657.1 COG2128 Uncharacterized conserved protein; hypothetical protein 1584715 17442107 AFR_07255 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732793.1 1584134 R 1246995 CDS YP_008732794.1 556564369 17442108 complement(1584761..1585189) 1 NC_022657.1 hypothetical protein 1585189 17442108 AFR_07260 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732794.1 1584761 R 1246995 CDS YP_008732795.1 556564370 17442109 complement(1585207..1585464) 1 NC_022657.1 hypothetical protein 1585464 17442109 AFR_07265 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732795.1 1585207 R 1246995 CDS YP_008732796.1 556564371 17442110 1585764..1587050 1 NC_022657.1 COG0542 ATPases with chaperone activity, ATP-binding subunit; hypothetical protein 1587050 17442110 AFR_07270 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732796.1 1585764 D 1246995 CDS YP_008732797.1 556564372 17442112 complement(1587361..1588371) 1 NC_022657.1 COG2267 Lysophospholipase; hypothetical protein 1588371 17442112 AFR_07275 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732797.1 1587361 R 1246995 CDS YP_008732798.1 556564373 17442113 1588542..1589264 1 NC_022657.1 COG0629 Single-stranded DNA-binding protein; single-strand binding protein 1589264 17442113 AFR_07280 Actinoplanes friuliensis DSM 7358 single-strand binding protein YP_008732798.1 1588542 D 1246995 CDS YP_008732799.1 556564374 17442114 1589992..1590858 1 NC_022657.1 COG1270 Cobalamin biosynthesis protein CobD/CbiB; cobalamin biosynthesis protein CobD 1590858 17442114 AFR_07285 Actinoplanes friuliensis DSM 7358 cobalamin biosynthesis protein CobD YP_008732799.1 1589992 D 1246995 CDS YP_008732800.1 556564375 17442115 1590855..1592387 1 NC_022657.1 COG1492 Cobyric acid synthase; putative cobyric acid synthase CobQ 1592387 17442115 AFR_07290 Actinoplanes friuliensis DSM 7358 putative cobyric acid synthase CobQ YP_008732800.1 1590855 D 1246995 CDS YP_008732801.1 556564376 17442116 1592384..1592992 1 NC_022657.1 COG0563 Adenylate kinase and related kinases; hypothetical protein 1592992 17442116 AFR_07295 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732801.1 1592384 D 1246995 CDS YP_008732802.1 556564377 17442117 1593033..1594103 1 NC_022657.1 COG0501 Zn-dependent protease with chaperone function; peptidase M48 Ste24p 1594103 17442117 AFR_07300 Actinoplanes friuliensis DSM 7358 peptidase M48 Ste24p YP_008732802.1 1593033 D 1246995 CDS YP_008732803.1 556564378 17442118 1594165..1595514 1 NC_022657.1 COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases; hypothetical protein 1595514 17442118 AFR_07305 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732803.1 1594165 D 1246995 CDS YP_008732804.1 556564379 17442119 1595516..1596973 1 NC_022657.1 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases; putative FAD-dependent monooxygenase 1596973 17442119 AFR_07310 Actinoplanes friuliensis DSM 7358 putative FAD-dependent monooxygenase YP_008732804.1 1595516 D 1246995 CDS YP_008732805.1 556564380 17442120 1596970..1597770 1 NC_022657.1 COG0561 Predicted hydrolases of the HAD superfamily; hypothetical protein 1597770 17442120 AFR_07315 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732805.1 1596970 D 1246995 CDS YP_008732806.1 556564381 17442121 1597964..1598170 1 NC_022657.1 hypothetical protein 1598170 17442121 AFR_07320 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732806.1 1597964 D 1246995 CDS YP_008732807.1 556564382 17442122 1599071..1600624 1 NC_022657.1 COG1793 ATP-dependent DNA ligase; ATP-dependent DNA ligase 1600624 ligB 17442122 ligB Actinoplanes friuliensis DSM 7358 ATP-dependent DNA ligase YP_008732807.1 1599071 D 1246995 CDS YP_008732808.1 556564383 17442123 complement(1600616..1601050) 1 NC_022657.1 hypothetical protein 1601050 17442123 AFR_07330 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732808.1 1600616 R 1246995 CDS YP_008732809.1 556564384 17442124 complement(1601061..1601879) 1 NC_022657.1 COG3346 Uncharacterized conserved protein; Surfeit locus protein 1 1601879 17442124 AFR_07335 Actinoplanes friuliensis DSM 7358 Surfeit locus protein 1 YP_008732809.1 1601061 R 1246995 CDS YP_008732810.1 556564385 17442125 1601990..1603591 1 NC_022657.1 COG1797 Cobyrinic acid a,c-diamide synthase; cobyrinic acid a,c-diamide synthase 1603591 17442125 AFR_07340 Actinoplanes friuliensis DSM 7358 cobyrinic acid a,c-diamide synthase YP_008732810.1 1601990 D 1246995 CDS YP_008732811.1 556564386 17442126 1603657..1604244 1 NC_022657.1 hypothetical protein 1604244 17442126 AFR_07345 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732811.1 1603657 D 1246995 CDS YP_008732812.1 556564387 17442127 complement(1604333..1606483) 1 NC_022657.1 COG0744 Membrane carboxypeptidase (penicillin-binding protein); putative glycosyltransferase 1606483 17442127 AFR_07350 Actinoplanes friuliensis DSM 7358 putative glycosyltransferase YP_008732812.1 1604333 R 1246995 CDS YP_008732813.1 556564388 17442128 complement(1606508..1606753) 1 NC_022657.1 hypothetical protein 1606753 17442128 AFR_07355 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732813.1 1606508 R 1246995 CDS YP_008732814.1 556564389 17442129 1606760..1607728 1 NC_022657.1 COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; hypothetical protein 1607728 17442129 AFR_07360 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732814.1 1606760 D 1246995 CDS YP_008732815.1 556564390 17442130 1607725..1608777 1 NC_022657.1 COG2038 NaMN:DMB phosphoribosyltransferase; putative nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase 1608777 17442130 AFR_07365 Actinoplanes friuliensis DSM 7358 putative nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase YP_008732815.1 1607725 D 1246995 CDS YP_008732816.1 556564391 17442131 1608774..1609967 1 NC_022657.1 COG1648 Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain); uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase 1609967 17442131 AFR_07370 Actinoplanes friuliensis DSM 7358 uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase YP_008732816.1 1608774 D 1246995 CDS YP_008732817.1 556564392 17442132 1610014..1610370 1 NC_022657.1 COG0346 Lactoylglutathione lyase and related lyases; hypothetical protein 1610370 17442132 AFR_07375 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732817.1 1610014 D 1246995 CDS YP_008732818.1 556564393 17442133 complement(1610359..1611837) 1 NC_022657.1 COG0380 Trehalose-6-phosphate synthase; putative trehalose-6-phosphate synthase 1611837 17442133 AFR_07380 Actinoplanes friuliensis DSM 7358 putative trehalose-6-phosphate synthase YP_008732818.1 1610359 R 1246995 CDS YP_008732819.1 556564394 17442134 1612018..1612497 1 NC_022657.1 hypothetical protein 1612497 17442134 AFR_07385 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732819.1 1612018 D 1246995 CDS YP_008732820.1 556564395 17442135 1612618..1614294 1 NC_022657.1 COG0488 ATPase components of ABC transporters with duplicated ATPase domains; ABC transporter ATP-binding protein 1614294 17442135 AFR_07390 Actinoplanes friuliensis DSM 7358 ABC transporter ATP-binding protein YP_008732820.1 1612618 D 1246995 CDS YP_008732821.1 556564396 17442136 1614308..1614691 1 NC_022657.1 COG0824 Predicted thioesterase; hypothetical protein 1614691 17442136 AFR_07395 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732821.1 1614308 D 1246995 CDS YP_008732822.1 556564397 17442137 1614691..1615353 1 NC_022657.1 hypothetical protein 1615353 17442137 AFR_07400 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732822.1 1614691 D 1246995 CDS YP_008732823.1 556564398 17442138 1615609..1616067 1 NC_022657.1 hypothetical protein 1616067 17442138 AFR_07405 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732823.1 1615609 D 1246995 CDS YP_008732824.1 556564399 17442139 complement(1616126..1617385) 1 NC_022657.1 hypothetical protein 1617385 17442139 AFR_07410 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732824.1 1616126 R 1246995 CDS YP_008732825.1 556564400 17442140 complement(1617447..1617872) 1 NC_022657.1 COG2346 Truncated hemoglobins; putative globin-like protein 1617872 17442140 AFR_07415 Actinoplanes friuliensis DSM 7358 putative globin-like protein YP_008732825.1 1617447 R 1246995 CDS YP_008732826.1 556564401 17442141 complement(1617869..1619224) 1 NC_022657.1 COG0477 Permeases of the major facilitator superfamily; major facilitator transporter 1619224 17442141 AFR_07420 Actinoplanes friuliensis DSM 7358 major facilitator transporter YP_008732826.1 1617869 R 1246995 CDS YP_008732827.1 556564402 17442142 complement(1619448..1620536) 1 NC_022657.1 COG0668 Small-conductance mechanosensitive channel; MscS family small conductance mechanosensitive ion channel 1620536 17442142 AFR_07425 Actinoplanes friuliensis DSM 7358 MscS family small conductance mechanosensitive ion channel YP_008732827.1 1619448 R 1246995 CDS YP_008732828.1 556564403 17442143 1620849..1621292 1 NC_022657.1 COG1403 Restriction endonuclease; putative endonuclease 1621292 17442143 AFR_07430 Actinoplanes friuliensis DSM 7358 putative endonuclease YP_008732828.1 1620849 D 1246995 CDS YP_008732829.1 556564404 17442144 1622212..1622814 1 NC_022657.1 COG1511 Predicted membrane protein; hypothetical protein 1622814 17442144 AFR_07435 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732829.1 1622212 D 1246995 CDS YP_008732830.1 556564405 17442145 complement(1623224..1624018) 1 NC_022657.1 COG3764 Sortase (surface protein transpeptidase); peptidase C60 sortase A and B 1624018 17442145 AFR_07440 Actinoplanes friuliensis DSM 7358 peptidase C60 sortase A and B YP_008732830.1 1623224 R 1246995 CDS YP_008732831.1 556564406 17442146 complement(1624028..1624516) 1 NC_022657.1 hypothetical protein 1624516 17442146 AFR_07445 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732831.1 1624028 R 1246995 CDS YP_008732832.1 556564407 17442147 1624740..1625018 1 NC_022657.1 hypothetical protein 1625018 17442147 AFR_07450 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732832.1 1624740 D 1246995 CDS YP_008732833.1 556564408 17442148 1625005..1625496 1 NC_022657.1 hypothetical protein 1625496 17442148 AFR_07455 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732833.1 1625005 D 1246995 CDS YP_008732834.1 556564409 17442149 complement(1625493..1626053) 1 NC_022657.1 COG4636 Uncharacterized protein conserved in cyanobacteria; hypothetical protein 1626053 17442149 AFR_07460 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732834.1 1625493 R 1246995 CDS YP_008732835.1 556564410 17442150 complement(1626176..1628734) 1 NC_022657.1 COG0308 Aminopeptidase N; putative aminopeptidase 1628734 17442150 AFR_07465 Actinoplanes friuliensis DSM 7358 putative aminopeptidase YP_008732835.1 1626176 R 1246995 CDS YP_008732836.1 556564411 17442151 1628861..1629487 1 NC_022657.1 hypothetical protein 1629487 17442151 AFR_07470 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732836.1 1628861 D 1246995 CDS YP_008732837.1 556564412 17442152 1629555..1629797 1 NC_022657.1 hypothetical protein 1629797 17442152 AFR_07475 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732837.1 1629555 D 1246995 CDS YP_008732838.1 556564413 17442153 1629859..1631049 1 NC_022657.1 COG4198 Uncharacterized conserved protein; hypothetical protein 1631049 17442153 AFR_07480 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732838.1 1629859 D 1246995 CDS YP_008732839.1 556564414 17442154 1631049..1631966 1 NC_022657.1 COG0657 Esterase/lipase; hypothetical protein 1631966 17442154 AFR_07485 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732839.1 1631049 D 1246995 CDS YP_008732840.1 556564415 17442155 1631990..1632463 1 NC_022657.1 COG0698 Ribose 5-phosphate isomerase RpiB; putative ribose-5-phosphate isomerase 1632463 17442155 AFR_07490 Actinoplanes friuliensis DSM 7358 putative ribose-5-phosphate isomerase YP_008732840.1 1631990 D 1246995 CDS YP_008732841.1 556564416 17442156 complement(1632467..1632919) 1 NC_022657.1 hypothetical protein 1632919 17442156 AFR_07495 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732841.1 1632467 R 1246995 CDS YP_008732842.1 556564417 17442157 complement(1632982..1634223) 1 NC_022657.1 COG4552 Predicted acetyltransferase involved in intracellular survival and related acetyltransferases; hypothetical protein 1634223 17442157 AFR_07500 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732842.1 1632982 R 1246995 CDS YP_008732843.1 556564418 17442158 1634324..1634911 1 NC_022657.1 DNA-directed RNA polymerase II subunit RPB1 1634911 17442158 AFR_07505 Actinoplanes friuliensis DSM 7358 DNA-directed RNA polymerase II subunit RPB1 YP_008732843.1 1634324 D 1246995 CDS YP_008732844.1 556564419 17442159 complement(1634904..1635794) 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); putative short-chain dehydrogenase 1635794 17442159 AFR_07510 Actinoplanes friuliensis DSM 7358 putative short-chain dehydrogenase YP_008732844.1 1634904 R 1246995 CDS YP_008732845.1 556564420 17442160 complement(1635830..1636954) 1 NC_022657.1 COG2340 Uncharacterized protein with SCP/PR1 domains; RNA polymerase ECF-subfamily sigma factor 1636954 17442160 AFR_07515 Actinoplanes friuliensis DSM 7358 RNA polymerase ECF-subfamily sigma factor YP_008732845.1 1635830 R 1246995 CDS YP_008732846.1 556564421 17442161 1637099..1637479 1 NC_022657.1 hypothetical protein 1637479 17442161 AFR_07520 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732846.1 1637099 D 1246995 CDS YP_008732847.1 556564422 17442162 complement(1637445..1637978) 1 NC_022657.1 hypothetical protein 1637978 17442162 AFR_07525 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732847.1 1637445 R 1246995 CDS YP_008732848.1 556564423 17442163 1638053..1638817 1 NC_022657.1 COG2207 AraC-type DNA-binding domain-containing proteins; putative AraC-family transcriptional regulator 1638817 17442163 AFR_07530 Actinoplanes friuliensis DSM 7358 putative AraC-family transcriptional regulator YP_008732848.1 1638053 D 1246995 CDS YP_008732849.1 556564424 17442166 1639164..1640513 1 NC_022657.1 COG0544 FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor); trigger factor 1640513 tig 17442166 tig Actinoplanes friuliensis DSM 7358 trigger factor YP_008732849.1 1639164 D 1246995 CDS YP_008732850.1 556564425 17442167 1640716..1641345 1 NC_022657.1 COG0740 Protease subunit of ATP-dependent Clp proteases; endopeptidase Clp 1641345 17442167 AFR_07540 Actinoplanes friuliensis DSM 7358 endopeptidase Clp YP_008732850.1 1640716 D 1246995 CDS YP_008732851.1 556564426 17442168 1641357..1642013 1 NC_022657.1 COG0740 Protease subunit of ATP-dependent Clp proteases; ATP-dependent Clp protease, protease subunit 1642013 17442168 AFR_07545 Actinoplanes friuliensis DSM 7358 ATP-dependent Clp protease, protease subunit YP_008732851.1 1641357 D 1246995 CDS YP_008732852.1 556564427 17442169 1642247..1643539 1 NC_022657.1 COG1219 ATP-dependent protease Clp, ATPase subunit; ATP-dependent protease ATP-binding subunit ClpX 1643539 clpX 17442169 clpX Actinoplanes friuliensis DSM 7358 ATP-dependent protease ATP-binding subunit ClpX YP_008732852.1 1642247 D 1246995 CDS YP_008732853.1 556564428 17442170 1643677..1644183 1 NC_022657.1 hypothetical protein 1644183 17442170 AFR_07555 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732853.1 1643677 D 1246995 CDS YP_008732854.1 556564429 17442171 1644202..1644999 1 NC_022657.1 COG0388 Predicted amidohydrolase; putative carbon-nitrogen hydrolase 1644999 17442171 AFR_07560 Actinoplanes friuliensis DSM 7358 putative carbon-nitrogen hydrolase YP_008732854.1 1644202 D 1246995 CDS YP_008732855.1 556564430 17442172 complement(1645006..1645737) 1 NC_022657.1 hypothetical protein 1645737 17442172 AFR_07565 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732855.1 1645006 R 1246995 CDS YP_008732856.1 556564431 17442173 complement(1646383..1646598) 1 NC_022657.1 hypothetical protein 1646598 17442173 AFR_07570 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732856.1 1646383 R 1246995 CDS YP_008732857.1 556564432 17442177 complement(1652541..1653209) 1 NC_022657.1 hypothetical protein 1653209 17442177 AFR_07575 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732857.1 1652541 R 1246995 CDS YP_008732858.1 556564433 17442178 1653290..1655929 1 NC_022657.1 COG0525 Valyl-tRNA synthetase; valyl-tRNA ligase 1655929 valS 17442178 valS Actinoplanes friuliensis DSM 7358 valyl-tRNA ligase YP_008732858.1 1653290 D 1246995 CDS YP_008732859.1 556564434 17442179 1655944..1657251 1 NC_022657.1 COG0285 Folylpolyglutamate synthase; putative folylpolyglutamate synthase 1657251 17442179 AFR_07585 Actinoplanes friuliensis DSM 7358 putative folylpolyglutamate synthase YP_008732859.1 1655944 D 1246995 CDS YP_008732860.1 556564435 17442180 1657248..1657610 1 NC_022657.1 hypothetical protein 1657610 17442180 AFR_07590 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732860.1 1657248 D 1246995 CDS YP_008732861.1 556564436 17442181 complement(1657668..1658375) 1 NC_022657.1 COG0346 Lactoylglutathione lyase and related lyases; Zonadhesin 1658375 17442181 AFR_07595 Actinoplanes friuliensis DSM 7358 Zonadhesin YP_008732861.1 1657668 R 1246995 CDS YP_008732862.1 556564437 17442182 1659363..1659749 1 NC_022657.1 hypothetical protein 1659749 17442182 AFR_07600 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732862.1 1659363 D 1246995 CDS YP_008732863.1 556564438 17442183 1660912..1661262 1 NC_022657.1 hypothetical protein 1661262 17442183 AFR_07605 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732863.1 1660912 D 1246995 CDS YP_008732864.1 556564439 17442184 1661329..1661751 1 NC_022657.1 COG0105 Nucleoside diphosphate kinase; multifunctional nucleoside diphosphate kinase/apyrimidinic endonuclease/3'-phosphodiesterase 1661751 ndk 17442184 ndk Actinoplanes friuliensis DSM 7358 multifunctional nucleoside diphosphate kinase/apyrimidinic endonuclease/3'-phosphodiesterase YP_008732864.1 1661329 D 1246995 CDS YP_008732865.1 556564440 17442185 complement(1661748..1662188) 1 NC_022657.1 COG2128 Uncharacterized conserved protein; alkylhydroperoxidase 1662188 17442185 AFR_07615 Actinoplanes friuliensis DSM 7358 alkylhydroperoxidase YP_008732865.1 1661748 R 1246995 CDS YP_008732866.1 556564441 17442186 complement(1662374..1663933) 1 NC_022657.1 COG3540 Phosphodiesterase/alkaline phosphatase D; alkaline phosphatase 1663933 17442186 AFR_07620 Actinoplanes friuliensis DSM 7358 alkaline phosphatase YP_008732866.1 1662374 R 1246995 CDS YP_008732867.1 556564442 17442187 1664335..1667451 1 NC_022657.1 COG0060 Isoleucyl-tRNA synthetase; isoleucyl-tRNA ligase 1667451 ileS 17442187 ileS Actinoplanes friuliensis DSM 7358 isoleucyl-tRNA ligase YP_008732867.1 1664335 D 1246995 CDS YP_008732868.1 556564443 17442188 1667587..1668273 1 NC_022657.1 COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase; putative acyltransferase 1668273 17442188 AFR_07630 Actinoplanes friuliensis DSM 7358 putative acyltransferase YP_008732868.1 1667587 D 1246995 CDS YP_008732869.1 556564444 17442189 complement(1668270..1669739) 1 NC_022657.1 COG3046 Uncharacterized protein related to deoxyribodipyrimidine photolyase; putative deoxyribodipyrimidine photolyase-related protein 1669739 17442189 AFR_07635 Actinoplanes friuliensis DSM 7358 putative deoxyribodipyrimidine photolyase-related protein YP_008732869.1 1668270 R 1246995 CDS YP_008732870.1 556564445 17442190 complement(1669749..1671230) 1 NC_022657.1 hypothetical protein 1671230 17442190 AFR_07640 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732870.1 1669749 R 1246995 CDS YP_008732871.1 556564446 17442191 1671456..1672247 1 NC_022657.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); Carboxylesterase bioH 1672247 17442191 AFR_07645 Actinoplanes friuliensis DSM 7358 Carboxylesterase bioH YP_008732871.1 1671456 D 1246995 CDS YP_008732872.1 556564447 17442192 1672281..1674755 1 NC_022657.1 COG2202 FOG: PAS/PAC domain; putative magnesium/manganese-dependent protein phosphatase with GAF domain 1674755 17442192 AFR_07650 Actinoplanes friuliensis DSM 7358 putative magnesium/manganese-dependent protein phosphatase with GAF domain YP_008732872.1 1672281 D 1246995 CDS YP_008732873.1 556564448 17442193 1674752..1675096 1 NC_022657.1 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); hypothetical protein 1675096 17442193 AFR_07655 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732873.1 1674752 D 1246995 CDS YP_008732874.1 556564449 17442194 1675117..1677069 1 NC_022657.1 COG1032 Fe-S oxidoreductase; hypothetical protein 1677069 17442194 AFR_07660 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732874.1 1675117 D 1246995 CDS YP_008732875.1 556564450 17442195 1677124..1677858 1 NC_022657.1 COG5011 Uncharacterized protein conserved in bacteria; hypothetical protein 1677858 17442195 AFR_07665 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732875.1 1677124 D 1246995 CDS YP_008732876.1 556564451 17442196 1678250..1681135 1 NC_022657.1 COG1530 Ribonucleases G and E; hypothetical protein 1681135 17442196 AFR_07670 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732876.1 1678250 D 1246995 CDS YP_008732877.1 556564452 17442197 1681262..1681789 1 NC_022657.1 hypothetical protein 1681789 17442197 AFR_07675 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732877.1 1681262 D 1246995 CDS YP_008732878.1 556564453 17442198 1681950..1682264 1 NC_022657.1 COG0261 Ribosomal protein L21; 50S ribosomal protein L21 1682264 rplU 17442198 rplU Actinoplanes friuliensis DSM 7358 50S ribosomal protein L21 YP_008732878.1 1681950 D 1246995 CDS YP_008732879.1 556564454 17442199 1682273..1682530 1 NC_022657.1 COG0211 Ribosomal protein L27; 50S ribosomal protein L27 1682530 rpmA 17442199 rpmA Actinoplanes friuliensis DSM 7358 50S ribosomal protein L27 YP_008732879.1 1682273 D 1246995 CDS YP_008732880.1 556564455 17442200 1682605..1684119 1 NC_022657.1 COG0536 Predicted GTPase; GTPase CgtA 1684119 obgE 17442200 obgE Actinoplanes friuliensis DSM 7358 GTPase CgtA YP_008732880.1 1682605 D 1246995 CDS YP_008732881.1 556564456 17442201 1684178..1684633 1 NC_022657.1 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; GCN5-like N-acetyltransferase 1684633 17442201 AFR_07695 Actinoplanes friuliensis DSM 7358 GCN5-like N-acetyltransferase YP_008732881.1 1684178 D 1246995 CDS YP_008732882.1 556564457 17442202 complement(1684620..1686173) 1 NC_022657.1 Beta-galactoside-specific lectin 3 1686173 17442202 AFR_07700 Actinoplanes friuliensis DSM 7358 Beta-galactoside-specific lectin 3 YP_008732882.1 1684620 R 1246995 CDS YP_008732883.1 556564458 17442203 complement(1686170..1686712) 1 NC_022657.1 hypothetical protein 1686712 17442203 AFR_07705 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732883.1 1686170 R 1246995 CDS YP_008732884.1 556564459 17442204 1686851..1689361 1 NC_022657.1 COG0308 Aminopeptidase N; aminopeptidase 1689361 17442204 AFR_07710 Actinoplanes friuliensis DSM 7358 aminopeptidase YP_008732884.1 1686851 D 1246995 CDS YP_008732885.1 556564460 17442205 1689421..1690968 1 NC_022657.1 COG0642 Signal transduction histidine kinase; PAS/PAC sensor hybrid histidine kinase 1690968 17442205 AFR_07715 Actinoplanes friuliensis DSM 7358 PAS/PAC sensor hybrid histidine kinase YP_008732885.1 1689421 D 1246995 CDS YP_008732886.1 556564461 17442206 1690983..1691588 1 NC_022657.1 COG1057 Nicotinic acid mononucleotide adenylyltransferase; putative nicotinate-nucleotide adenylyltransferase 1691588 17442206 AFR_07720 Actinoplanes friuliensis DSM 7358 putative nicotinate-nucleotide adenylyltransferase YP_008732886.1 1690983 D 1246995 CDS YP_008732887.1 556564462 17442207 1691657..1692058 1 NC_022657.1 COG0799 Uncharacterized homolog of plant Iojap protein; hypothetical protein 1692058 17442207 AFR_07725 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732887.1 1691657 D 1246995 CDS YP_008732888.1 556564463 17442208 1692055..1692690 1 NC_022657.1 COG0406 Fructose-2,6-bisphosphatase; putative phosphoglycerate mutase 1692690 17442208 AFR_07730 Actinoplanes friuliensis DSM 7358 putative phosphoglycerate mutase YP_008732888.1 1692055 D 1246995 CDS YP_008732889.1 556564464 17442209 1692772..1693122 1 NC_022657.1 hypothetical protein 1693122 17442209 AFR_07735 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732889.1 1692772 D 1246995 CDS YP_008732890.1 556564465 17442210 1693147..1693998 1 NC_022657.1 COG1307 Uncharacterized protein conserved in bacteria; hypothetical protein 1693998 17442210 AFR_07740 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732890.1 1693147 D 1246995 CDS YP_008732891.1 556564466 17442211 complement(1693995..1695041) 1 NC_022657.1 hypothetical protein 1695041 17442211 AFR_07745 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732891.1 1693995 R 1246995 CDS YP_008732892.1 556564467 17442212 complement(1695072..1695860) 1 NC_022657.1 COG2890 Methylase of polypeptide chain release factors; methyltransferase 1695860 17442212 AFR_07750 Actinoplanes friuliensis DSM 7358 methyltransferase YP_008732892.1 1695072 R 1246995 CDS YP_008732893.1 556564468 17442213 1696314..1697246 1 NC_022657.1 COG1555 DNA uptake protein and related DNA-binding proteins; ComE operon protein 1 1697246 17442213 AFR_07755 Actinoplanes friuliensis DSM 7358 ComE operon protein 1 YP_008732893.1 1696314 D 1246995 CDS YP_008732894.1 556564469 17442214 1697663..1699654 1 NC_022657.1 COG0658 Predicted membrane metal-binding protein; ComE operon protein 3 1699654 17442214 AFR_07760 Actinoplanes friuliensis DSM 7358 ComE operon protein 3 YP_008732894.1 1697663 D 1246995 CDS YP_008732895.1 556564470 17442215 1699726..1700460 1 NC_022657.1 COG0702 Predicted nucleoside-diphosphate-sugar epimerases; hypothetical protein 1700460 17442215 AFR_07765 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732895.1 1699726 D 1246995 CDS YP_008732896.1 556564471 17442216 1700556..1702973 1 NC_022657.1 COG3537 Putative alpha-1,2-mannosidase; alpha-1,2-mannosidase 1702973 17442216 AFR_07770 Actinoplanes friuliensis DSM 7358 alpha-1,2-mannosidase YP_008732896.1 1700556 D 1246995 CDS YP_008732897.1 556564472 17442217 1703332..1704306 1 NC_022657.1 COG1466 DNA polymerase III, delta subunit; putative DNA polymerase III delta subunit 1704306 17442217 AFR_07775 Actinoplanes friuliensis DSM 7358 putative DNA polymerase III delta subunit YP_008732897.1 1703332 D 1246995 CDS YP_008732898.1 556564473 17442218 1704303..1704854 1 NC_022657.1 Collagen alpha-5(VI) chain 1704854 17442218 AFR_07780 Actinoplanes friuliensis DSM 7358 Collagen alpha-5(VI) chain YP_008732898.1 1704303 D 1246995 CDS YP_008732899.1 556564474 17442219 complement(1705198..1705464) 1 NC_022657.1 COG0268 Ribosomal protein S20; 30S ribosomal protein S20 1705464 17442219 AFR_07785 Actinoplanes friuliensis DSM 7358 30S ribosomal protein S20 YP_008732899.1 1705198 R 1246995 CDS YP_008732900.1 556564475 17442220 complement(1705613..1706581) 1 NC_022657.1 COG0515 Serine/threonine protein kinase; Protein kinase 3 1706581 17442220 AFR_07790 Actinoplanes friuliensis DSM 7358 Protein kinase 3 YP_008732900.1 1705613 R 1246995 CDS YP_008732901.1 556564476 17442221 1706634..1707167 1 NC_022657.1 hypothetical protein 1707167 17442221 AFR_07795 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732901.1 1706634 D 1246995 CDS YP_008732902.1 556564477 17442222 1707259..1708047 1 NC_022657.1 COG2258 Uncharacterized protein conserved in bacteria; hypothetical protein 1708047 17442222 AFR_07800 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732902.1 1707259 D 1246995 CDS YP_008732903.1 556564478 17442223 1708168..1710042 1 NC_022657.1 COG0481 Membrane GTPase LepA; GTP-binding protein LepA 1710042 17442223 AFR_07805 Actinoplanes friuliensis DSM 7358 GTP-binding protein LepA YP_008732903.1 1708168 D 1246995 CDS YP_008732904.1 556564479 17442224 1710123..1710401 1 NC_022657.1 COG2261 Predicted membrane protein; hypothetical protein 1710401 17442224 AFR_07810 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732904.1 1710123 D 1246995 CDS YP_008732905.1 556564480 17442225 complement(1711732..1713375) 1 NC_022657.1 COG2202 FOG: PAS/PAC domain; hypothetical protein 1713375 17442225 AFR_07815 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732905.1 1711732 R 1246995 CDS YP_008732906.1 556564481 17442226 complement(1713533..1714363) 1 NC_022657.1 hypothetical protein 1714363 17442226 AFR_07820 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732906.1 1713533 R 1246995 CDS YP_008732907.1 556564482 17442227 complement(1714431..1715207) 1 NC_022657.1 COG1024 Enoyl-CoA hydratase/carnithine racemase; enoyl-CoA hydratase/isomerase 1715207 17442227 AFR_07825 Actinoplanes friuliensis DSM 7358 enoyl-CoA hydratase/isomerase YP_008732907.1 1714431 R 1246995 CDS YP_008732908.1 556564483 17442228 1715244..1716455 1 NC_022657.1 COG0635 Coproporphyrinogen III oxidase and related Fe-S oxidoreductases; oxygen-independent coproporphyrinogen III oxidase 1716455 17442228 AFR_07830 Actinoplanes friuliensis DSM 7358 oxygen-independent coproporphyrinogen III oxidase YP_008732908.1 1715244 D 1246995 CDS YP_008732909.1 556564484 17442229 complement(1716510..1717271) 1 NC_022657.1 COG3296 Uncharacterized protein conserved in bacteria; hypothetical protein 1717271 17442229 AFR_07835 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732909.1 1716510 R 1246995 CDS YP_008732910.1 556564485 17442230 1717448..1718470 1 NC_022657.1 COG1420 Transcriptional regulator of heat shock gene; heat-inducible transcription repressor 1718470 hrcA 17442230 hrcA Actinoplanes friuliensis DSM 7358 heat-inducible transcription repressor YP_008732910.1 1717448 D 1246995 CDS YP_008732911.1 556564486 17442231 1718532..1719668 1 NC_022657.1 COG0484 DnaJ-class molecular chaperone with C-terminal Zn finger domain; putative chaperone protein DnaJ 1719668 17442231 AFR_07845 Actinoplanes friuliensis DSM 7358 putative chaperone protein DnaJ YP_008732911.1 1718532 D 1246995 CDS YP_008732912.1 556564487 17442232 1720905..1721639 1 NC_022657.1 COG1385 Uncharacterized protein conserved in bacteria; hypothetical protein 1721639 17442232 AFR_07850 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732912.1 1720905 D 1246995 CDS YP_008732913.1 556564488 17442233 1721771..1722715 1 NC_022657.1 COG0609 ABC-type Fe3+-siderophore transport system, permease component; ABC transporter permease 1722715 17442233 AFR_07855 Actinoplanes friuliensis DSM 7358 ABC transporter permease YP_008732913.1 1721771 D 1246995 CDS YP_008732914.1 556564489 17442234 1722712..1723755 1 NC_022657.1 COG4779 ABC-type enterobactin transport system, permease component; ABC transporter permease 1723755 17442234 AFR_07860 Actinoplanes friuliensis DSM 7358 ABC transporter permease YP_008732914.1 1722712 D 1246995 CDS YP_008732915.1 556564490 17442235 1723765..1724559 1 NC_022657.1 COG1120 ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components; ABC transporter ATP-binding protein 1724559 17442235 AFR_07865 Actinoplanes friuliensis DSM 7358 ABC transporter ATP-binding protein YP_008732915.1 1723765 D 1246995 CDS YP_008732916.1 556564491 17442236 1724598..1724810 1 NC_022657.1 COG3251 Uncharacterized protein conserved in bacteria; MbtH domain-containing protein 1724810 17442236 AFR_07870 Actinoplanes friuliensis DSM 7358 MbtH domain-containing protein YP_008732916.1 1724598 D 1246995 CDS YP_008732917.1 556564492 17442237 1724818..1726509 1 NC_022657.1 COG1132 ABC-type multidrug transport system, ATPase and permease components; putative ABC transporter ATPase and permease protein 1726509 17442237 AFR_07875 Actinoplanes friuliensis DSM 7358 putative ABC transporter ATPase and permease protein YP_008732917.1 1724818 D 1246995 CDS YP_008732918.1 556564493 17442238 1726506..1728254 1 NC_022657.1 COG1132 ABC-type multidrug transport system, ATPase and permease components; putative ABC transporter ATPase and permease protein 1728254 17442238 AFR_07880 Actinoplanes friuliensis DSM 7358 putative ABC transporter ATPase and permease protein YP_008732918.1 1726506 D 1246995 CDS YP_008732919.1 556564494 17442239 complement(1728265..1729008) 1 NC_022657.1 hypothetical protein 1729008 17442239 AFR_07885 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732919.1 1728265 R 1246995 CDS YP_008732920.1 556564495 17442240 complement(1729076..1730092) 1 NC_022657.1 COG0614 ABC-type Fe3+-hydroxamate transport system, periplasmic component; periplasmic iron-transport lipoprotein 1730092 17442240 AFR_07890 Actinoplanes friuliensis DSM 7358 periplasmic iron-transport lipoprotein YP_008732920.1 1729076 R 1246995 CDS YP_008732921.1 556564496 17442241 1730207..1730626 1 NC_022657.1 COG0853 Aspartate 1-decarboxylase; aspartate 1-decarboxylase 1730626 17442241 AFR_07895 Actinoplanes friuliensis DSM 7358 aspartate 1-decarboxylase YP_008732921.1 1730207 D 1246995 CDS YP_008732922.1 556564497 17442242 1730664..1731341 1 NC_022657.1 COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; hypothetical protein 1731341 17442242 AFR_07900 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732922.1 1730664 D 1246995 CDS YP_008732923.1 556564498 17442243 1731402..1732079 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); putative short-chain dehydrogenase 1732079 17442243 AFR_07905 Actinoplanes friuliensis DSM 7358 putative short-chain dehydrogenase YP_008732923.1 1731402 D 1246995 CDS YP_008732924.1 556564499 17442244 complement(1732080..1733033) 1 NC_022657.1 COG0223 Methionyl-tRNA formyltransferase; formyltransferase 1733033 17442244 AFR_07910 Actinoplanes friuliensis DSM 7358 formyltransferase YP_008732924.1 1732080 R 1246995 CDS YP_008732925.1 556564500 17442245 1733137..1734438 1 NC_022657.1 COG3486 Lysine/ornithine N-monooxygenase; Siderophore biosynthesis protein, monooxygenase 1734438 17442245 AFR_07915 Actinoplanes friuliensis DSM 7358 Siderophore biosynthesis protein, monooxygenase YP_008732925.1 1733137 D 1246995 CDS YP_008732926.1 556564501 17442246 1734449..1735015 1 NC_022657.1 hypothetical protein 1735015 17442246 AFR_07920 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732926.1 1734449 D 1246995 CDS YP_008732927.1 556564502 17442247 1735138..1735890 1 NC_022657.1 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; arginase/agmatinase/formimionoglutamate hydrolase arginase family-like protein 1735890 17442247 AFR_07925 Actinoplanes friuliensis DSM 7358 arginase/agmatinase/formimionoglutamate hydrolase arginase family-like protein YP_008732927.1 1735138 D 1246995 CDS YP_008732928.1 556564503 17442248 1736073..1736534 1 NC_022657.1 hypothetical protein 1736534 17442248 AFR_07930 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732928.1 1736073 D 1246995 CDS YP_008732929.1 556564504 17442249 complement(1736582..1738954) 1 NC_022657.1 COG1472 Beta-glucosidase-related glycosidases; putative glycosyl hydrolase 1738954 17442249 AFR_07935 Actinoplanes friuliensis DSM 7358 putative glycosyl hydrolase YP_008732929.1 1736582 R 1246995 CDS YP_008732930.1 556564505 17442250 complement(1738989..1739750) 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); short-chain dehydrogenase/reductase sdr 1739750 17442250 AFR_07940 Actinoplanes friuliensis DSM 7358 short-chain dehydrogenase/reductase sdr YP_008732930.1 1738989 R 1246995 CDS YP_008732931.1 556564506 17442251 1739774..1740124 1 NC_022657.1 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases; histidine triad (HIT) protein 1740124 17442251 AFR_07945 Actinoplanes friuliensis DSM 7358 histidine triad (HIT) protein YP_008732931.1 1739774 D 1246995 CDS YP_008732932.1 556564507 17442252 1740121..1741494 1 NC_022657.1 COG1680 Beta-lactamase class C and other penicillin binding proteins; putative beta-lactamase 1741494 17442252 AFR_07950 Actinoplanes friuliensis DSM 7358 putative beta-lactamase YP_008732932.1 1740121 D 1246995 CDS YP_008732933.1 556564508 17442253 1741659..1742720 1 NC_022657.1 COG1702 Phosphate starvation-inducible protein PhoH, predicted ATPase; putative phosphate starvation-induced protein PhoH 1742720 17442253 AFR_07955 Actinoplanes friuliensis DSM 7358 putative phosphate starvation-induced protein PhoH YP_008732933.1 1741659 D 1246995 CDS YP_008732934.1 556564509 17442254 1742739..1743209 1 NC_022657.1 COG0319 Predicted metal-dependent hydrolase; metal-binding heat shock protein 1743209 17442254 AFR_07960 Actinoplanes friuliensis DSM 7358 metal-binding heat shock protein YP_008732934.1 1742739 D 1246995 CDS YP_008732935.1 556564510 17442255 1743215..1744582 1 NC_022657.1 COG1253 Hemolysins and related proteins containing CBS domains; hypothetical protein 1744582 17442255 AFR_07965 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732935.1 1743215 D 1246995 CDS YP_008732936.1 556564511 17442256 1744575..1744946 1 NC_022657.1 hypothetical protein 1744946 17442256 AFR_07970 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732936.1 1744575 D 1246995 CDS YP_008732937.1 556564512 17442257 1745813..1746949 1 NC_022657.1 COG1159 GTPase; GTPase Era 1746949 era 17442257 era Actinoplanes friuliensis DSM 7358 GTPase Era YP_008732937.1 1745813 D 1246995 CDS YP_008732938.1 556564513 17442258 1747025..1748080 1 NC_022657.1 COG1835 Predicted acyltransferases; Putative O-acetyltransferase 1748080 17442258 AFR_07980 Actinoplanes friuliensis DSM 7358 Putative O-acetyltransferase YP_008732938.1 1747025 D 1246995 CDS YP_008732939.1 556564514 17442259 1748077..1749333 1 NC_022657.1 COG0477 Permeases of the major facilitator superfamily; Major Facilitator Superfamily transporter 1749333 17442259 AFR_07985 Actinoplanes friuliensis DSM 7358 Major Facilitator Superfamily transporter YP_008732939.1 1748077 D 1246995 CDS YP_008732940.1 556564515 17442260 complement(1749311..1750114) 1 NC_022657.1 COG3595 Uncharacterized conserved protein; hypothetical protein 1750114 17442260 AFR_07990 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732940.1 1749311 R 1246995 CDS YP_008732941.1 556564516 17442261 1750226..1751011 1 NC_022657.1 COG1381 Recombinational DNA repair protein (RecF pathway); DNA repair protein RecO 1751011 recO 17442261 recO Actinoplanes friuliensis DSM 7358 DNA repair protein RecO YP_008732941.1 1750226 D 1246995 CDS YP_008732942.1 556564517 17442262 1751008..1751787 1 NC_022657.1 COG0020 Undecaprenyl pyrophosphate synthase; putative undecaprenyl diphosphate synthase 1751787 17442262 AFR_08000 Actinoplanes friuliensis DSM 7358 putative undecaprenyl diphosphate synthase YP_008732942.1 1751008 D 1246995 CDS YP_008732943.1 556564518 17442263 1751790..1752347 1 NC_022657.1 COG0406 Fructose-2,6-bisphosphatase; phosphoglycerate mutase 1752347 17442263 AFR_08005 Actinoplanes friuliensis DSM 7358 phosphoglycerate mutase YP_008732943.1 1751790 D 1246995 CDS YP_008732944.1 556564519 17442264 complement(1752337..1752996) 1 NC_022657.1 COG0546 Predicted phosphatases; haloacid dehalogenase domain protein hydrolase 1752996 17442264 AFR_08010 Actinoplanes friuliensis DSM 7358 haloacid dehalogenase domain protein hydrolase YP_008732944.1 1752337 R 1246995 CDS YP_008732945.1 556564520 17442265 complement(1753008..1753304) 1 NC_022657.1 COG0011 Uncharacterized conserved protein; hypothetical protein 1753304 17442265 AFR_08015 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732945.1 1753008 R 1246995 CDS YP_008732946.1 556564521 17442266 1754804..1754986 1 NC_022657.1 hypothetical protein 1754986 17442266 AFR_08020 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732946.1 1754804 D 1246995 CDS YP_008732947.1 556564522 17442267 complement(1755156..1755644) 1 NC_022657.1 hypothetical protein 1755644 17442267 AFR_08025 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732947.1 1755156 R 1246995 CDS YP_008732948.1 556564523 17442268 complement(1755641..1757356) 1 NC_022657.1 COG1387 Histidinol phosphatase and related hydrolases of the PHP family; hypothetical protein 1757356 17442268 AFR_08030 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732948.1 1755641 R 1246995 CDS YP_008732949.1 556564524 17442269 complement(1757462..1757836) 1 NC_022657.1 COG1714 Predicted membrane protein/domain; hypothetical protein 1757836 17442269 AFR_08035 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732949.1 1757462 R 1246995 CDS YP_008732950.1 556564525 17442270 complement(1758041..1758844) 1 NC_022657.1 COG0619 ABC-type cobalt transport system, permease component CbiQ and related transporters; putative cobalt transport protein 1758844 17442270 AFR_08040 Actinoplanes friuliensis DSM 7358 putative cobalt transport protein YP_008732950.1 1758041 R 1246995 CDS YP_008732951.1 556564526 17442271 complement(1758841..1760232) 1 NC_022657.1 COG1122 ABC-type cobalt transport system, ATPase component; putative ABC transporter ATP-binding protein 1760232 17442271 AFR_08045 Actinoplanes friuliensis DSM 7358 putative ABC transporter ATP-binding protein YP_008732951.1 1758841 R 1246995 CDS YP_008732952.1 556564527 17442272 complement(1760236..1760817) 1 NC_022657.1 COG4721 Predicted membrane protein; hypothetical protein 1760817 17442272 AFR_08050 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732952.1 1760236 R 1246995 CDS YP_008732953.1 556564528 17442273 1761053..1761868 1 NC_022657.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); alpha/beta hydrolase fold protein 1761868 17442273 AFR_08055 Actinoplanes friuliensis DSM 7358 alpha/beta hydrolase fold protein YP_008732953.1 1761053 D 1246995 CDS YP_008732954.1 556564529 17442274 1761937..1762464 1 NC_022657.1 hypothetical protein 1762464 17442274 AFR_08060 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732954.1 1761937 D 1246995 CDS YP_008732955.1 556564530 17442275 complement(1762442..1763053) 1 NC_022657.1 hypothetical protein 1763053 17442275 AFR_08065 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732955.1 1762442 R 1246995 CDS YP_008732956.1 556564531 17442276 complement(1763078..1763485) 1 NC_022657.1 COG0735 Fe2+/Zn2+ uptake regulation proteins; Ferric uptake regulation protein 1763485 17442276 AFR_08070 Actinoplanes friuliensis DSM 7358 Ferric uptake regulation protein YP_008732956.1 1763078 R 1246995 CDS YP_008732957.1 556564532 17442277 complement(1763482..1763778) 1 NC_022657.1 COG0640 Predicted transcriptional regulators; putative ArsR-family transcriptional regulator 1763778 17442277 AFR_08075 Actinoplanes friuliensis DSM 7358 putative ArsR-family transcriptional regulator YP_008732957.1 1763482 R 1246995 CDS YP_008732958.1 556564533 17442278 complement(1763775..1764656) 1 NC_022657.1 COG1108 ABC-type Mn2+/Zn2+ transport systems, permease components; Chelated iron transport system membrane protein yfeD 1764656 17442278 AFR_08080 Actinoplanes friuliensis DSM 7358 Chelated iron transport system membrane protein yfeD YP_008732958.1 1763775 R 1246995 CDS YP_008732959.1 556564534 17442279 complement(1764704..1765483) 1 NC_022657.1 COG1121 ABC-type Mn/Zn transport systems, ATPase component; zinc transport system ATP-binding protein 1765483 17442279 AFR_08085 Actinoplanes friuliensis DSM 7358 zinc transport system ATP-binding protein YP_008732959.1 1764704 R 1246995 CDS YP_008732960.1 556564535 17442280 complement(1765480..1766412) 1 NC_022657.1 COG0803 ABC-type metal ion transport system, periplasmic component/surface adhesin; putative ABC transporter substrate-binding protein 1766412 17442280 AFR_08090 Actinoplanes friuliensis DSM 7358 putative ABC transporter substrate-binding protein YP_008732960.1 1765480 R 1246995 CDS YP_008732961.1 556564536 17442281 complement(1766461..1766721) 1 NC_022657.1 hypothetical protein 1766721 17442281 AFR_08095 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732961.1 1766461 R 1246995 CDS YP_008732962.1 556564537 17442282 1766756..1767097 1 NC_022657.1 COG2329 Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides; hypothetical protein 1767097 17442282 AFR_08100 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732962.1 1766756 D 1246995 CDS YP_008732963.1 556564538 17442283 1767166..1767615 1 NC_022657.1 hypothetical protein 1767615 17442283 AFR_08105 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732963.1 1767166 D 1246995 CDS YP_008732964.1 556564539 17442284 1767675..1769054 1 NC_022657.1 COG0423 Glycyl-tRNA synthetase (class II); glycyl-tRNA ligase 1769054 17442284 AFR_08110 Actinoplanes friuliensis DSM 7358 glycyl-tRNA ligase YP_008732964.1 1767675 D 1246995 CDS YP_008732965.1 556564540 17442285 complement(1769051..1769455) 1 NC_022657.1 COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family; hypothetical protein 1769455 17442285 AFR_08115 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732965.1 1769051 R 1246995 CDS YP_008732966.1 556564541 17442286 1769551..1770693 1 NC_022657.1 COG0042 tRNA-dihydrouridine synthase; putative tRNA-dihydrouridine synthase 1770693 17442286 AFR_08120 Actinoplanes friuliensis DSM 7358 putative tRNA-dihydrouridine synthase YP_008732966.1 1769551 D 1246995 CDS YP_008732967.1 556564542 17442287 1770690..1771274 1 NC_022657.1 NIPSNAP family containing protein 1771274 17442287 AFR_08125 Actinoplanes friuliensis DSM 7358 NIPSNAP family containing protein YP_008732967.1 1770690 D 1246995 CDS YP_008732968.1 556564543 17442288 complement(1771333..1771704) 1 NC_022657.1 hypothetical protein 1771704 17442288 AFR_08130 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732968.1 1771333 R 1246995 CDS YP_008732969.1 556564544 17442289 complement(1771746..1772231) 1 NC_022657.1 COG2018 Uncharacterized distant relative of homeotic protein bithoraxoid; hypothetical protein 1772231 17442289 AFR_08135 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732969.1 1771746 R 1246995 CDS YP_008732970.1 556564545 17442290 complement(1772284..1773285) 1 NC_022657.1 ADAM 12 protein 1773285 17442290 AFR_08140 Actinoplanes friuliensis DSM 7358 ADAM 12 protein YP_008732970.1 1772284 R 1246995 CDS YP_008732971.1 556564546 17442291 complement(1773311..1773640) 1 NC_022657.1 hypothetical protein 1773640 17442291 AFR_08145 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732971.1 1773311 R 1246995 CDS YP_008732972.1 556564547 17442292 complement(1773894..1774394) 1 NC_022657.1 hypothetical protein 1774394 17442292 AFR_08150 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732972.1 1773894 R 1246995 CDS YP_008732973.1 556564548 17442293 1774555..1774917 1 NC_022657.1 hypothetical protein 1774917 17442293 AFR_08155 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732973.1 1774555 D 1246995 CDS YP_008732974.1 556564549 17442294 complement(1774911..1776500) 1 NC_022657.1 COG0840 Methyl-accepting chemotaxis protein; Methyl-accepting chemotaxis protein mcpB 1776500 17442294 AFR_08160 Actinoplanes friuliensis DSM 7358 Methyl-accepting chemotaxis protein mcpB YP_008732974.1 1774911 R 1246995 CDS YP_008732975.1 556564550 17442295 1776545..1777765 1 NC_022657.1 COG0232 dGTP triphosphohydrolase; dGTPase 1777765 17442295 AFR_08165 Actinoplanes friuliensis DSM 7358 dGTPase YP_008732975.1 1776545 D 1246995 CDS YP_008732976.1 556564551 17442296 1777785..1779632 1 NC_022657.1 COG0358 DNA primase (bacterial type); putative DNA primase 1779632 17442296 AFR_08170 Actinoplanes friuliensis DSM 7358 putative DNA primase YP_008732976.1 1777785 D 1246995 CDS YP_008732977.1 556564552 17442297 1779629..1780159 1 NC_022657.1 hypothetical protein 1780159 17442297 AFR_08175 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732977.1 1779629 D 1246995 CDS YP_008732978.1 556564553 17442298 1780193..1781113 1 NC_022657.1 COG1131 ABC-type multidrug transport system, ATPase component; putative ABC transporter ATP-binding protein 1781113 17442298 AFR_08180 Actinoplanes friuliensis DSM 7358 putative ABC transporter ATP-binding protein YP_008732978.1 1780193 D 1246995 CDS YP_008732979.1 556564554 17442299 1781113..1781865 1 NC_022657.1 COG0842 ABC-type multidrug transport system, permease component; Nodulation protein J 1781865 17442299 AFR_08185 Actinoplanes friuliensis DSM 7358 Nodulation protein J YP_008732979.1 1781113 D 1246995 CDS YP_008732980.1 556564555 17442300 1781879..1782688 1 NC_022657.1 COG0842 ABC-type multidrug transport system, permease component; ABC transporter permease 1782688 17442300 AFR_08190 Actinoplanes friuliensis DSM 7358 ABC transporter permease YP_008732980.1 1781879 D 1246995 CDS YP_008732981.1 556564556 17442301 1782853..1783968 1 NC_022657.1 COG1295 Predicted membrane protein; hypothetical protein 1783968 17442301 AFR_08195 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732981.1 1782853 D 1246995 CDS YP_008732982.1 556564557 17442302 1784199..1785377 1 NC_022657.1 COG1940 Transcriptional regulator/sugar kinase; putative ROK-family transcriptional regulator 1785377 17442302 AFR_08200 Actinoplanes friuliensis DSM 7358 putative ROK-family transcriptional regulator YP_008732982.1 1784199 D 1246995 CDS YP_008732983.1 556564558 17442303 1785374..1786918 1 NC_022657.1 COG1129 ABC-type sugar transport system, ATPase component; putative ABC transporter ATP-binding protein 1786918 17442303 AFR_08205 Actinoplanes friuliensis DSM 7358 putative ABC transporter ATP-binding protein YP_008732983.1 1785374 D 1246995 CDS YP_008732984.1 556564559 17442304 1786915..1787991 1 NC_022657.1 COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components; ABC transporter permease 1787991 17442304 AFR_08210 Actinoplanes friuliensis DSM 7358 ABC transporter permease YP_008732984.1 1786915 D 1246995 CDS YP_008732985.1 556564560 17442305 1788053..1789096 1 NC_022657.1 COG1879 ABC-type sugar transport system, periplasmic component; putative ABC transporter substrate-binding protein 1789096 17442305 AFR_08215 Actinoplanes friuliensis DSM 7358 putative ABC transporter substrate-binding protein YP_008732985.1 1788053 D 1246995 CDS YP_008732986.1 556564561 17442306 1789130..1790314 1 NC_022657.1 COG0673 Predicted dehydrogenases and related proteins; putative oxidoreductase 1790314 17442306 AFR_08220 Actinoplanes friuliensis DSM 7358 putative oxidoreductase YP_008732986.1 1789130 D 1246995 CDS YP_008732987.1 556564562 17442307 1790827..1791927 1 NC_022657.1 hypothetical protein 1791927 17442307 AFR_08225 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732987.1 1790827 D 1246995 CDS YP_008732988.1 556564563 17442308 1792113..1793120 1 NC_022657.1 COG1082 Sugar phosphate isomerases/epimerases; xylose isomerase domain-containing protein 1793120 17442308 AFR_08230 Actinoplanes friuliensis DSM 7358 xylose isomerase domain-containing protein YP_008732988.1 1792113 D 1246995 CDS YP_008732989.1 556564564 17442309 complement(1793183..1793491) 1 NC_022657.1 hypothetical protein 1793491 17442309 AFR_08235 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732989.1 1793183 R 1246995 CDS YP_008732990.1 556564565 17442311 1794089..1795357 1 NC_022657.1 COG1233 Phytoene dehydrogenase and related proteins; Protoporphyrinogen oxidase 1795357 17442311 AFR_08240 Actinoplanes friuliensis DSM 7358 Protoporphyrinogen oxidase YP_008732990.1 1794089 D 1246995 CDS YP_008732991.1 556564566 17442313 complement(1795754..1795987) 1 NC_022657.1 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase; hypothetical protein 1795987 17442313 AFR_08245 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732991.1 1795754 R 1246995 CDS YP_008732992.1 556564567 17442314 1796193..1796399 1 NC_022657.1 hypothetical protein 1796399 17442314 AFR_08250 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732992.1 1796193 D 1246995 CDS YP_008732993.1 556564568 17442315 1797234..1797914 1 NC_022657.1 COG0637 Predicted phosphatase/phosphohexomutase; HAD-superfamily hydrolase 1797914 17442315 AFR_08255 Actinoplanes friuliensis DSM 7358 HAD-superfamily hydrolase YP_008732993.1 1797234 D 1246995 CDS YP_008732994.1 556564569 17442316 1798345..1799049 1 NC_022657.1 COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; class I/II aminotransferase 1799049 17442316 AFR_08260 Actinoplanes friuliensis DSM 7358 class I/II aminotransferase YP_008732994.1 1798345 D 1246995 CDS YP_008732995.1 556564570 17442317 1800217..1800375 1 NC_022657.1 COG0141 Histidinol dehydrogenase; bifunctional histidinal dehydrogenase/ histidinol dehydrogenase 1800375 hisD 17442317 hisD Actinoplanes friuliensis DSM 7358 bifunctional histidinal dehydrogenase/ histidinol dehydrogenase YP_008732995.1 1800217 D 1246995 CDS YP_008732996.1 556564571 17442318 complement(1800729..1800914) 1 NC_022657.1 hypothetical protein 1800914 17442318 AFR_08270 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732996.1 1800729 R 1246995 CDS YP_008732997.1 556564572 17442319 1801266..1801649 1 NC_022657.1 hypothetical protein 1801649 17442319 AFR_08275 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732997.1 1801266 D 1246995 CDS YP_008732998.1 556564573 17442320 complement(1802449..1802823) 1 NC_022657.1 COG4584 Transposase and inactivated derivatives; transposase 1802823 17442320 AFR_08280 Actinoplanes friuliensis DSM 7358 transposase YP_008732998.1 1802449 R 1246995 CDS YP_008732999.1 556564574 17442321 complement(1803598..1807053) 1 NC_022657.1 COG2319 FOG: WD40 repeat; hypothetical protein 1807053 17442321 AFR_08285 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008732999.1 1803598 R 1246995 CDS YP_008733000.1 556564575 17442322 complement(1807526..1807972) 1 NC_022657.1 hypothetical protein 1807972 17442322 AFR_08290 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733000.1 1807526 R 1246995 CDS YP_008733001.1 556564576 17442323 complement(1807976..1808593) 1 NC_022657.1 hypothetical protein 1808593 17442323 AFR_08295 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733001.1 1807976 R 1246995 CDS YP_008733002.1 556564577 17442324 complement(1809017..1809322) 1 NC_022657.1 hypothetical protein 1809322 17442324 AFR_08300 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733002.1 1809017 R 1246995 CDS YP_008733003.1 556564578 17442325 complement(1809322..1809714) 1 NC_022657.1 hypothetical protein 1809714 17442325 AFR_08305 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733003.1 1809322 R 1246995 CDS YP_008733004.1 556564579 17442326 complement(1809855..1810769) 1 NC_022657.1 COG0477 Permeases of the major facilitator superfamily; major facilitator transporter 1810769 17442326 AFR_08310 Actinoplanes friuliensis DSM 7358 major facilitator transporter YP_008733004.1 1809855 R 1246995 CDS YP_008733005.1 556564580 17442327 complement(1810840..1812240) 1 NC_022657.1 COG2072 Predicted flavoprotein involved in K+ transport; FAD dependent oxidoreductase 1812240 17442327 AFR_08315 Actinoplanes friuliensis DSM 7358 FAD dependent oxidoreductase YP_008733005.1 1810840 R 1246995 CDS YP_008733006.1 556564581 17442328 complement(1812252..1812803) 1 NC_022657.1 COG1247 Sortase and related acyltransferases; GCN5-like N-acetyltransferase 1812803 17442328 AFR_08320 Actinoplanes friuliensis DSM 7358 GCN5-like N-acetyltransferase YP_008733006.1 1812252 R 1246995 CDS YP_008733007.1 556564582 17442329 1812848..1813180 1 NC_022657.1 COG0640 Predicted transcriptional regulators; ArsR family transcriptional regulator 1813180 17442329 AFR_08325 Actinoplanes friuliensis DSM 7358 ArsR family transcriptional regulator YP_008733007.1 1812848 D 1246995 CDS YP_008733008.1 556564583 17442330 1813240..1813881 1 NC_022657.1 COG0580 Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family); low molecular weight phosphotyrosine protein phosphatase 1813881 17442330 AFR_08330 Actinoplanes friuliensis DSM 7358 low molecular weight phosphotyrosine protein phosphatase YP_008733008.1 1813240 D 1246995 CDS YP_008733009.1 556564584 17442331 1813893..1814273 1 NC_022657.1 COG0394 Protein-tyrosine-phosphatase; protein-tyrosine phosphatase, low molecular weight 1814273 17442331 AFR_08335 Actinoplanes friuliensis DSM 7358 protein-tyrosine phosphatase, low molecular weight YP_008733009.1 1813893 D 1246995 CDS YP_008733010.1 556564585 17442332 complement(1814280..1814627) 1 NC_022657.1 hypothetical protein 1814627 17442332 AFR_08340 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733010.1 1814280 R 1246995 CDS YP_008733011.1 556564586 17442333 1814746..1817340 1 NC_022657.1 COG0457 FOG: TPR repeat; hypothetical protein 1817340 17442333 AFR_08345 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733011.1 1814746 D 1246995 CDS YP_008733012.1 556564587 17442334 1817343..1817903 1 NC_022657.1 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; ECF subfamily RNA polymerase sigma-24 subunit 1817903 17442334 AFR_08350 Actinoplanes friuliensis DSM 7358 ECF subfamily RNA polymerase sigma-24 subunit YP_008733012.1 1817343 D 1246995 CDS YP_008733013.1 556564588 17442335 1817968..1818435 1 NC_022657.1 hypothetical protein 1818435 17442335 AFR_08355 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733013.1 1817968 D 1246995 CDS YP_008733014.1 556564589 17442336 1818445..1819944 1 NC_022657.1 COG1404 Subtilisin-like serine proteases; serine protease 1819944 17442336 AFR_08360 Actinoplanes friuliensis DSM 7358 serine protease YP_008733014.1 1818445 D 1246995 CDS YP_008733015.1 556564590 17442337 1820068..1820547 1 NC_022657.1 hypothetical protein 1820547 17442337 AFR_08365 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733015.1 1820068 D 1246995 CDS YP_008733016.1 556564591 17442338 1820547..1821182 1 NC_022657.1 COG2931 RTX toxins and related Ca2+-binding proteins; hemolysin-type calcium-binding region 1821182 17442338 AFR_08370 Actinoplanes friuliensis DSM 7358 hemolysin-type calcium-binding region YP_008733016.1 1820547 D 1246995 CDS YP_008733017.1 556564592 17442339 1821242..1821748 1 NC_022657.1 hypothetical protein 1821748 17442339 AFR_08375 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733017.1 1821242 D 1246995 CDS YP_008733018.1 556564593 17442340 1821830..1822348 1 NC_022657.1 COG0262 Dihydrofolate reductase; reductase 1822348 17442340 AFR_08380 Actinoplanes friuliensis DSM 7358 reductase YP_008733018.1 1821830 D 1246995 CDS YP_008733019.1 556564594 17442341 complement(1822333..1823163) 1 NC_022657.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); alpha/beta hydrolase fold protein 1823163 17442341 AFR_08385 Actinoplanes friuliensis DSM 7358 alpha/beta hydrolase fold protein YP_008733019.1 1822333 R 1246995 CDS YP_008733020.1 556564595 17442342 complement(1823214..1823936) 1 NC_022657.1 COG2207 AraC-type DNA-binding domain-containing proteins; hypothetical protein 1823936 17442342 AFR_08390 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733020.1 1823214 R 1246995 CDS YP_008733021.1 556564596 17442343 complement(1823961..1827101) 1 NC_022657.1 COG0433 Predicted ATPase; hypothetical protein 1827101 17442343 AFR_08395 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733021.1 1823961 R 1246995 CDS YP_008733022.1 556564597 17442344 complement(1827098..1827745) 1 NC_022657.1 hypothetical protein 1827745 17442344 AFR_08400 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733022.1 1827098 R 1246995 CDS YP_008733023.1 556564598 17442345 complement(1827727..1828737) 1 NC_022657.1 COG2852 Uncharacterized protein conserved in bacteria; hypothetical protein 1828737 17442345 AFR_08405 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733023.1 1827727 R 1246995 CDS YP_008733024.1 556564599 17442346 complement(1828955..1829374) 1 NC_022657.1 COG3565 Predicted dioxygenase of extradiol dioxygenase family; glyoxalase/bleomycin resistance protein/dioxygenase 1829374 17442346 AFR_08410 Actinoplanes friuliensis DSM 7358 glyoxalase/bleomycin resistance protein/dioxygenase YP_008733024.1 1828955 R 1246995 CDS YP_008733025.1 556564600 17442347 complement(1829371..1830063) 1 NC_022657.1 COG1309 Transcriptional regulator; regulatory protein TetR 1830063 17442347 AFR_08415 Actinoplanes friuliensis DSM 7358 regulatory protein TetR YP_008733025.1 1829371 R 1246995 CDS YP_008733026.1 556564601 17442348 1830129..1830851 1 NC_022657.1 hypothetical protein 1830851 17442348 AFR_08420 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733026.1 1830129 D 1246995 CDS YP_008733027.1 556564602 17442349 1830797..1831534 1 NC_022657.1 COG1357 Uncharacterized low-complexity proteins; pentapeptide repeat-containing protein 1831534 17442349 AFR_08425 Actinoplanes friuliensis DSM 7358 pentapeptide repeat-containing protein YP_008733027.1 1830797 D 1246995 CDS YP_008733028.1 556564603 17442350 complement(1831495..1831860) 1 NC_022657.1 hypothetical protein 1831860 17442350 AFR_08430 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733028.1 1831495 R 1246995 CDS YP_008733029.1 556564604 17442351 1831996..1832400 1 NC_022657.1 COG1396 Predicted transcriptional regulators; hypothetical protein 1832400 17442351 AFR_08435 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733029.1 1831996 D 1246995 CDS YP_008733030.1 556564605 17442352 1832499..1832987 1 NC_022657.1 hypothetical protein 1832987 17442352 AFR_08440 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733030.1 1832499 D 1246995 CDS YP_008733031.1 556564606 17442353 1833020..1834717 1 NC_022657.1 COG1472 Beta-glucosidase-related glycosidases; glycosyl hydrolase 1834717 17442353 AFR_08445 Actinoplanes friuliensis DSM 7358 glycosyl hydrolase YP_008733031.1 1833020 D 1246995 CDS YP_008733032.1 556564607 17442354 1834851..1835246 1 NC_022657.1 COG1544 Ribosome-associated protein Y (PSrp-1); hypothetical protein 1835246 17442354 AFR_08450 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733032.1 1834851 D 1246995 CDS YP_008733033.1 556564608 17442355 1835347..1836918 1 NC_022657.1 COG1012 NAD-dependent aldehyde dehydrogenases; aldehyde dehydrogenase 1836918 17442355 AFR_08455 Actinoplanes friuliensis DSM 7358 aldehyde dehydrogenase YP_008733033.1 1835347 D 1246995 CDS YP_008733034.1 556564609 17442356 1836947..1837768 1 NC_022657.1 COG0566 rRNA methylases; tRNA/rRNA methyltransferase SpoU 1837768 17442356 AFR_08460 Actinoplanes friuliensis DSM 7358 tRNA/rRNA methyltransferase SpoU YP_008733034.1 1836947 D 1246995 CDS YP_008733035.1 556564610 17442357 1837800..1838666 1 NC_022657.1 COG2334 Putative homoserine kinase type II (protein kinase fold); aminoglycoside phosphotransferase 1838666 17442357 AFR_08465 Actinoplanes friuliensis DSM 7358 aminoglycoside phosphotransferase YP_008733035.1 1837800 D 1246995 CDS YP_008733036.1 556564611 17442358 1838974..1839141 1 NC_022657.1 XRE family transcriptional regulator 1839141 17442358 AFR_08470 Actinoplanes friuliensis DSM 7358 XRE family transcriptional regulator YP_008733036.1 1838974 D 1246995 CDS YP_008733037.1 556564612 17442359 1839327..1841921 1 NC_022657.1 COG3899 Predicted ATPase; LuxR family transcriptional regulator 1841921 17442359 AFR_08475 Actinoplanes friuliensis DSM 7358 LuxR family transcriptional regulator YP_008733037.1 1839327 D 1246995 CDS YP_008733038.1 556564613 17442360 1841932..1842744 1 NC_022657.1 COG0500 SAM-dependent methyltransferases; putative methyltransferase 1842744 17442360 AFR_08480 Actinoplanes friuliensis DSM 7358 putative methyltransferase YP_008733038.1 1841932 D 1246995 CDS YP_008733039.1 556564614 17442361 complement(1842754..1843233) 1 NC_022657.1 protein CdfA 1843233 17442361 AFR_08485 Actinoplanes friuliensis DSM 7358 protein CdfA YP_008733039.1 1842754 R 1246995 CDS YP_008733040.1 556564615 17442362 complement(1843282..1844172) 1 NC_022657.1 Cortactin-binding protein 2 1844172 17442362 AFR_08490 Actinoplanes friuliensis DSM 7358 Cortactin-binding protein 2 YP_008733040.1 1843282 R 1246995 CDS YP_008733041.1 556564616 17442363 1844417..1846486 1 NC_022657.1 COG0840 Methyl-accepting chemotaxis protein; Methyl-accepting chemotaxis aspartate transducer 1846486 17442363 AFR_08495 Actinoplanes friuliensis DSM 7358 Methyl-accepting chemotaxis aspartate transducer YP_008733041.1 1844417 D 1246995 CDS YP_008733042.1 556564617 17442364 complement(1846481..1846903) 1 NC_022657.1 COG2453 Predicted protein-tyrosine phosphatase; hypothetical protein 1846903 17442364 AFR_08500 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733042.1 1846481 R 1246995 CDS YP_008733043.1 556564618 17442365 complement(1846900..1848609) 1 NC_022657.1 COG2376 Dihydroxyacetone kinase; dihydroxyacetone kinase 1848609 17442365 AFR_08505 Actinoplanes friuliensis DSM 7358 dihydroxyacetone kinase YP_008733043.1 1846900 R 1246995 CDS YP_008733044.1 556564619 17442366 1848785..1850443 1 NC_022657.1 COG0018 Arginyl-tRNA synthetase; arginyl-tRNA ligase 1850443 argS1 17442366 argS1 Actinoplanes friuliensis DSM 7358 arginyl-tRNA ligase YP_008733044.1 1848785 D 1246995 CDS YP_008733045.1 556564620 17442367 complement(1850379..1851377) 1 NC_022657.1 COG1714 Predicted membrane protein/domain; RDD domain-containing protein 1851377 17442367 AFR_08515 Actinoplanes friuliensis DSM 7358 RDD domain-containing protein YP_008733045.1 1850379 R 1246995 CDS YP_008733046.1 556564621 17442368 1851424..1852419 1 NC_022657.1 COG1300 Uncharacterized membrane protein; hypothetical protein 1852419 17442368 AFR_08520 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733046.1 1851424 D 1246995 CDS YP_008733047.1 556564622 17442369 1852442..1853074 1 NC_022657.1 COG0778 Nitroreductase; oxidoreductase 1853074 17442369 AFR_08525 Actinoplanes friuliensis DSM 7358 oxidoreductase YP_008733047.1 1852442 D 1246995 CDS YP_008733048.1 556564623 17442370 complement(1853079..1854398) 1 NC_022657.1 COG1721 Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain); hypothetical protein 1854398 17442370 AFR_08530 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733048.1 1853079 R 1246995 CDS YP_008733049.1 556564624 17442371 complement(1854406..1855362) 1 NC_022657.1 COG0714 MoxR-like ATPases; putative ATPase associated with various cellular activities 1855362 17442371 AFR_08535 Actinoplanes friuliensis DSM 7358 putative ATPase associated with various cellular activities YP_008733049.1 1854406 R 1246995 CDS YP_008733050.1 556564625 17442372 complement(1855377..1856708) 1 NC_022657.1 hypothetical protein 1856708 17442372 AFR_08540 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733050.1 1855377 R 1246995 CDS YP_008733051.1 556564626 17442373 complement(1856705..1857289) 1 NC_022657.1 hypothetical protein 1857289 17442373 AFR_08545 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733051.1 1856705 R 1246995 CDS YP_008733052.1 556564627 17442374 complement(1857286..1858122) 1 NC_022657.1 hypothetical protein 1858122 17442374 AFR_08550 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733052.1 1857286 R 1246995 CDS YP_008733053.1 556564628 17442375 1858276..1860045 1 NC_022657.1 COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; putative 2',3'-cyclic-nucleotide 2'-phosphodiesterase 1860045 17442375 AFR_08555 Actinoplanes friuliensis DSM 7358 putative 2',3'-cyclic-nucleotide 2'-phosphodiesterase YP_008733053.1 1858276 D 1246995 CDS YP_008733054.1 556564629 17442376 complement(1860113..1860946) 1 NC_022657.1 COG0169 Shikimate 5-dehydrogenase; hypothetical protein 1860946 17442376 AFR_08560 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733054.1 1860113 R 1246995 CDS YP_008733055.1 556564630 17442377 complement(1861030..1862301) 1 NC_022657.1 COG0681 Signal peptidase I; peptidase S26B, signal peptidase 1862301 17442377 AFR_08565 Actinoplanes friuliensis DSM 7358 peptidase S26B, signal peptidase YP_008733055.1 1861030 R 1246995 CDS YP_008733056.1 556564631 17442378 complement(1862517..1863359) 1 NC_022657.1 COG0789 Predicted transcriptional regulators; Multidrug-efflux transporter 1 regulator 1863359 17442378 AFR_08570 Actinoplanes friuliensis DSM 7358 Multidrug-efflux transporter 1 regulator YP_008733056.1 1862517 R 1246995 CDS YP_008733057.1 556564632 17442379 complement(1863404..1864912) 1 NC_022657.1 COG0515 Serine/threonine protein kinase; putative serine/threonine protein kinase 1864912 17442379 AFR_08575 Actinoplanes friuliensis DSM 7358 putative serine/threonine protein kinase YP_008733057.1 1863404 R 1246995 CDS YP_008733058.1 556564633 17442380 complement(1865122..1865673) 1 NC_022657.1 hypothetical protein 1865673 17442380 AFR_08580 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733058.1 1865122 R 1246995 CDS YP_008733059.1 556564634 17442381 1866016..1866345 1 NC_022657.1 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); hypothetical protein 1866345 17442381 AFR_08585 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733059.1 1866016 D 1246995 CDS YP_008733060.1 556564635 17442382 1866437..1867291 1 NC_022657.1 COG0515 Serine/threonine protein kinase; serine/threonine protein kinase 1867291 17442382 AFR_08590 Actinoplanes friuliensis DSM 7358 serine/threonine protein kinase YP_008733060.1 1866437 D 1246995 CDS YP_008733061.1 556564636 17442383 complement(1867288..1868130) 1 NC_022657.1 COG0496 Predicted acid phosphatase; putative stationary phase survival protein SurE 1868130 17442383 AFR_08595 Actinoplanes friuliensis DSM 7358 putative stationary phase survival protein SurE YP_008733061.1 1867288 R 1246995 CDS YP_008733062.1 556564637 17442384 complement(1868127..1869047) 1 NC_022657.1 COG1105 Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB); PfkB domain-containing protein 1869047 17442384 AFR_08600 Actinoplanes friuliensis DSM 7358 PfkB domain-containing protein YP_008733062.1 1868127 R 1246995 CDS YP_008733063.1 556564638 17442385 complement(1869121..1870203) 1 NC_022657.1 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases; monooxygenase FAD-binding protein 1870203 17442385 AFR_08605 Actinoplanes friuliensis DSM 7358 monooxygenase FAD-binding protein YP_008733063.1 1869121 R 1246995 CDS YP_008733064.1 556564639 17442386 1870293..1870958 1 NC_022657.1 COG1309 Transcriptional regulator; Tetracycline repressor protein class C 1870958 17442386 AFR_08610 Actinoplanes friuliensis DSM 7358 Tetracycline repressor protein class C YP_008733064.1 1870293 D 1246995 CDS YP_008733065.1 556564640 17442387 complement(1871342..1872358) 1 NC_022657.1 COG1064 Zn-dependent alcohol dehydrogenases; alcohol dehydrogenase 1872358 17442387 AFR_08615 Actinoplanes friuliensis DSM 7358 alcohol dehydrogenase YP_008733065.1 1871342 R 1246995 CDS YP_008733066.1 556564641 17442388 1872462..1873022 1 NC_022657.1 COG1309 Transcriptional regulator; TetR family transcriptional regulator 1873022 17442388 AFR_08620 Actinoplanes friuliensis DSM 7358 TetR family transcriptional regulator YP_008733066.1 1872462 D 1246995 CDS YP_008733067.1 556564642 17442389 complement(1873012..1874007) 1 NC_022657.1 COG0500 SAM-dependent methyltransferases; O-methyltransferase family protein 1874007 17442389 AFR_08625 Actinoplanes friuliensis DSM 7358 O-methyltransferase family protein YP_008733067.1 1873012 R 1246995 CDS YP_008733068.1 556564643 17442390 complement(1874051..1874362) 1 NC_022657.1 hypothetical protein 1874362 17442390 AFR_08630 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733068.1 1874051 R 1246995 CDS YP_008733069.1 556564644 17442391 complement(1874416..1875330) 1 NC_022657.1 COG1230 Co/Zn/Cd efflux system component; cation diffusion facilitator family transporter 1875330 17442391 AFR_08635 Actinoplanes friuliensis DSM 7358 cation diffusion facilitator family transporter YP_008733069.1 1874416 R 1246995 CDS YP_008733070.1 556564645 17442392 1875464..1876384 1 NC_022657.1 hypothetical protein 1876384 17442392 AFR_08640 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733070.1 1875464 D 1246995 CDS YP_008733071.1 556564646 17442393 complement(1876381..1878498) 1 NC_022657.1 COG3973 Superfamily I DNA and RNA helicases; putative helicase 1878498 17442393 AFR_08645 Actinoplanes friuliensis DSM 7358 putative helicase YP_008733071.1 1876381 R 1246995 CDS YP_008733072.1 556564647 17442394 complement(1878632..1879576) 1 NC_022657.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); hypothetical protein 1879576 17442394 AFR_08650 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733072.1 1878632 R 1246995 CDS YP_008733073.1 556564648 17442395 1879762..1880400 1 NC_022657.1 COG0288 Carbonic anhydrase; carbonic anhydrase 1880400 17442395 AFR_08655 Actinoplanes friuliensis DSM 7358 carbonic anhydrase YP_008733073.1 1879762 D 1246995 CDS YP_008733074.1 556564649 17442396 complement(1880508..1880837) 1 NC_022657.1 hypothetical protein 1880837 17442396 AFR_08660 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733074.1 1880508 R 1246995 CDS YP_008733075.1 556564650 17442397 1881103..1881594 1 NC_022657.1 hypothetical protein 1881594 17442397 AFR_08665 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733075.1 1881103 D 1246995 CDS YP_008733076.1 556564651 17442398 1881776..1883386 1 NC_022657.1 COG1472 Beta-glucosidase-related glycosidases; putative beta-N-acetylglucosaminidase 1883386 17442398 AFR_08670 Actinoplanes friuliensis DSM 7358 putative beta-N-acetylglucosaminidase YP_008733076.1 1881776 D 1246995 CDS YP_008733077.1 556564652 17442399 complement(1883339..1884253) 1 NC_022657.1 COG2207 AraC-type DNA-binding domain-containing proteins; AraC family transcriptional regulator 1884253 17442399 AFR_08675 Actinoplanes friuliensis DSM 7358 AraC family transcriptional regulator YP_008733077.1 1883339 R 1246995 CDS YP_008733078.1 556564653 17442400 1884376..1885191 1 NC_022657.1 COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases; NADPH:quinone reductase-like protein 1885191 17442400 AFR_08680 Actinoplanes friuliensis DSM 7358 NADPH:quinone reductase-like protein YP_008733078.1 1884376 D 1246995 CDS YP_008733079.1 556564654 17442401 complement(1885238..1886464) 1 NC_022657.1 COG0304 3-oxoacyl-(acyl-carrier-protein) synthase; beta-ketoacyl synthase 1886464 17442401 AFR_08685 Actinoplanes friuliensis DSM 7358 beta-ketoacyl synthase YP_008733079.1 1885238 R 1246995 CDS YP_008733080.1 556564655 17442402 complement(1886466..1886708) 1 NC_022657.1 COG0236 Acyl carrier protein; acyl carrier protein 1886708 acpP 17442402 acpP Actinoplanes friuliensis DSM 7358 acyl carrier protein YP_008733080.1 1886466 R 1246995 CDS YP_008733081.1 556564656 17442403 complement(1886761..1887711) 1 NC_022657.1 COG0332 3-oxoacyl-[acyl-carrier-protein] synthase III; 3-oxoacyl-(acyl carrier protein) synthase III 1887711 17442403 AFR_08695 Actinoplanes friuliensis DSM 7358 3-oxoacyl-(acyl carrier protein) synthase III YP_008733081.1 1886761 R 1246995 CDS YP_008733082.1 556564657 17442404 complement(1887743..1888702) 1 NC_022657.1 COG0331 (acyl-carrier-protein) S-malonyltransferase; acyl transferase 1888702 17442404 AFR_08700 Actinoplanes friuliensis DSM 7358 acyl transferase YP_008733082.1 1887743 R 1246995 CDS YP_008733083.1 556564658 17442405 complement(1888878..1889963) 1 NC_022657.1 COG2508 Regulator of polyketide synthase expression; hypothetical protein 1889963 17442405 AFR_08705 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733083.1 1888878 R 1246995 CDS YP_008733084.1 556564659 17442406 1890343..1890561 1 NC_022657.1 hypothetical protein 1890561 17442406 AFR_08710 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733084.1 1890343 D 1246995 CDS YP_008733085.1 556564660 17442407 1890669..1891232 1 NC_022657.1 COG1309 Transcriptional regulator; putative HTH-type transcriptional regulator 1891232 17442407 AFR_08715 Actinoplanes friuliensis DSM 7358 putative HTH-type transcriptional regulator YP_008733085.1 1890669 D 1246995 CDS YP_008733086.1 556564661 17442408 1891280..1891738 1 NC_022657.1 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; ECF subfamily RNA polymerase sigma-24 subunit 1891738 17442408 AFR_08720 Actinoplanes friuliensis DSM 7358 ECF subfamily RNA polymerase sigma-24 subunit YP_008733086.1 1891280 D 1246995 CDS YP_008733087.1 556564662 17442409 1891833..1892585 1 NC_022657.1 hypothetical protein 1892585 17442409 AFR_08725 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733087.1 1891833 D 1246995 CDS YP_008733088.1 556564663 17442410 complement(1892732..1893361) 1 NC_022657.1 hypothetical protein 1893361 17442410 AFR_08730 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733088.1 1892732 R 1246995 CDS YP_008733089.1 556564664 17442411 complement(1893755..1895116) 1 NC_022657.1 COG0008 Glutamyl- and glutaminyl-tRNA synthetases; glutamyl-tRNA ligase 1895116 gltX 17442411 gltX Actinoplanes friuliensis DSM 7358 glutamyl-tRNA ligase YP_008733089.1 1893755 R 1246995 CDS YP_008733090.1 556564665 17442412 1895348..1896679 1 NC_022657.1 COG3325 Chitinase; putative glycosyl hydrolase 1896679 17442412 AFR_08740 Actinoplanes friuliensis DSM 7358 putative glycosyl hydrolase YP_008733090.1 1895348 D 1246995 CDS YP_008733091.1 556564666 17442413 complement(1896700..1897953) 1 NC_022657.1 COG0477 Permeases of the major facilitator superfamily; major facilitator superfamily protein 1897953 17442413 AFR_08745 Actinoplanes friuliensis DSM 7358 major facilitator superfamily protein YP_008733091.1 1896700 R 1246995 CDS YP_008733092.1 556564667 17442414 complement(1897989..1898981) 1 NC_022657.1 hypothetical protein 1898981 17442414 AFR_08750 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733092.1 1897989 R 1246995 CDS YP_008733093.1 556564668 17442415 complement(1898978..1899574) 1 NC_022657.1 COG5516 Conserved protein containing a Zn-ribbon-like motif, possibly RNA-binding; hypothetical protein 1899574 17442415 AFR_08755 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733093.1 1898978 R 1246995 CDS YP_008733094.1 556564669 17442416 complement(1899651..1901762) 1 NC_022657.1 COG0840 Methyl-accepting chemotaxis protein; putative methyl-accepting chemotaxis protein 1901762 17442416 AFR_08760 Actinoplanes friuliensis DSM 7358 putative methyl-accepting chemotaxis protein YP_008733094.1 1899651 R 1246995 CDS YP_008733095.1 556564670 17442417 complement(1901858..1904596) 1 NC_022657.1 COG2609 Pyruvate dehydrogenase complex, dehydrogenase (E1) component; pyruvate dehydrogenase subunit E1 1904596 aceE 17442417 aceE Actinoplanes friuliensis DSM 7358 pyruvate dehydrogenase subunit E1 YP_008733095.1 1901858 R 1246995 CDS YP_008733096.1 556564671 17442418 complement(1904746..1905150) 1 NC_022657.1 COG0432 Uncharacterized conserved protein; hypothetical protein 1905150 17442418 AFR_08770 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733096.1 1904746 R 1246995 CDS YP_008733097.1 556564672 17442419 complement(1905320..1906117) 1 NC_022657.1 hypothetical protein 1906117 17442419 AFR_08775 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733097.1 1905320 R 1246995 CDS YP_008733098.1 556564673 17442420 complement(1906104..1907018) 1 NC_022657.1 COG1131 ABC-type multidrug transport system, ATPase component; ABC transporter ATP-binding protein 1907018 17442420 AFR_08780 Actinoplanes friuliensis DSM 7358 ABC transporter ATP-binding protein YP_008733098.1 1906104 R 1246995 CDS YP_008733099.1 556564674 17442421 complement(1907011..1907478) 1 NC_022657.1 COG1510 Predicted transcriptional regulators; hypothetical protein 1907478 17442421 AFR_08785 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733099.1 1907011 R 1246995 CDS YP_008733100.1 556564675 17442422 1907610..1909892 1 NC_022657.1 COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit; transketolase domain-containing protein 1909892 17442422 AFR_08790 Actinoplanes friuliensis DSM 7358 transketolase domain-containing protein YP_008733100.1 1907610 D 1246995 CDS YP_008733101.1 556564676 17442423 1910003..1910434 1 NC_022657.1 hypothetical protein 1910434 17442423 AFR_08795 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733101.1 1910003 D 1246995 CDS YP_008733102.1 556564677 17442424 1910526..1910990 1 NC_022657.1 COG1225 Peroxiredoxin; alkyl hydroperoxide reductase/ thiol specific antioxidant/ mal allergen 1910990 17442424 AFR_08800 Actinoplanes friuliensis DSM 7358 alkyl hydroperoxide reductase/ thiol specific antioxidant/ mal allergen YP_008733102.1 1910526 D 1246995 CDS YP_008733103.1 556564678 17442426 1911347..1911982 1 NC_022657.1 COG0500 SAM-dependent methyltransferases; type 11 methyltransferase 1911982 17442426 AFR_08805 Actinoplanes friuliensis DSM 7358 type 11 methyltransferase YP_008733103.1 1911347 D 1246995 CDS YP_008733104.1 556564679 17442427 1911979..1912728 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); short-chain dehydrogenase/reductase SDR 1912728 17442427 AFR_08810 Actinoplanes friuliensis DSM 7358 short-chain dehydrogenase/reductase SDR YP_008733104.1 1911979 D 1246995 CDS YP_008733105.1 556564680 17442428 complement(1912730..1913023) 1 NC_022657.1 Barstar (barnase inhibitor) 1913023 17442428 AFR_08815 Actinoplanes friuliensis DSM 7358 Barstar (barnase inhibitor) YP_008733105.1 1912730 R 1246995 CDS YP_008733106.1 556564681 17442429 1913054..1913554 1 NC_022657.1 COG3557 Uncharacterized domain/protein associated with RNAses G and E; hypothetical protein 1913554 17442429 AFR_08820 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733106.1 1913054 D 1246995 CDS YP_008733107.1 556564682 17442430 complement(1913527..1914378) 1 NC_022657.1 COG0500 SAM-dependent methyltransferases; type 11 methyltransferase 1914378 17442430 AFR_08825 Actinoplanes friuliensis DSM 7358 type 11 methyltransferase YP_008733107.1 1913527 R 1246995 CDS YP_008733108.1 556564683 17442431 complement(1914375..1915184) 1 NC_022657.1 aminoglycoside phosphotransferase 1915184 17442431 AFR_08830 Actinoplanes friuliensis DSM 7358 aminoglycoside phosphotransferase YP_008733108.1 1914375 R 1246995 CDS YP_008733109.1 556564684 17442432 complement(1915187..1915648) 1 NC_022657.1 COG1051 ADP-ribose pyrophosphatase; putative NUDIX hydrolase 1915648 17442432 AFR_08835 Actinoplanes friuliensis DSM 7358 putative NUDIX hydrolase YP_008733109.1 1915187 R 1246995 CDS YP_008733110.1 556564685 17442433 1915690..1916325 1 NC_022657.1 hypothetical protein 1916325 17442433 AFR_08840 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733110.1 1915690 D 1246995 CDS YP_008733111.1 556564686 17442434 1916558..1917145 1 NC_022657.1 hypothetical protein 1917145 17442434 AFR_08845 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733111.1 1916558 D 1246995 CDS YP_008733112.1 556564687 17442435 1917549..1918412 1 NC_022657.1 hypothetical protein 1918412 17442435 AFR_08850 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733112.1 1917549 D 1246995 CDS YP_008733113.1 556564688 17442436 complement(1918657..1919583) 1 NC_022657.1 COG0492 Thioredoxin reductase; oxidoreductase 1919583 17442436 AFR_08855 Actinoplanes friuliensis DSM 7358 oxidoreductase YP_008733113.1 1918657 R 1246995 CDS YP_008733114.1 556564689 17442437 1919643..1920224 1 NC_022657.1 COG1396 Predicted transcriptional regulators; transcriptional regulator 1920224 17442437 AFR_08860 Actinoplanes friuliensis DSM 7358 transcriptional regulator YP_008733114.1 1919643 D 1246995 CDS YP_008733115.1 556564690 17442438 complement(1920221..1921054) 1 NC_022657.1 COG0500 SAM-dependent methyltransferases; hypothetical protein 1921054 17442438 AFR_08865 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733115.1 1920221 R 1246995 CDS YP_008733116.1 556564691 17442439 complement(1921081..1921587) 1 NC_022657.1 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; N-acetyltransferase GCN5 1921587 17442439 AFR_08870 Actinoplanes friuliensis DSM 7358 N-acetyltransferase GCN5 YP_008733116.1 1921081 R 1246995 CDS YP_008733117.1 556564692 17442440 complement(1921799..1922395) 1 NC_022657.1 bifunctional DNA primase/polymerase 1922395 17442440 AFR_08875 Actinoplanes friuliensis DSM 7358 bifunctional DNA primase/polymerase YP_008733117.1 1921799 R 1246995 CDS YP_008733118.1 556564693 17442441 1922740..1923969 1 NC_022657.1 COG1396 Predicted transcriptional regulators; putative transcriptional regulator 1923969 17442441 AFR_08880 Actinoplanes friuliensis DSM 7358 putative transcriptional regulator YP_008733118.1 1922740 D 1246995 CDS YP_008733119.1 556564694 17442442 1923986..1924570 1 NC_022657.1 COG0452 Phosphopantothenoylcysteine synthetase/decarboxylase; Coenzyme A biosynthesis bifunctional protein coaBC 1924570 17442442 AFR_08885 Actinoplanes friuliensis DSM 7358 Coenzyme A biosynthesis bifunctional protein coaBC YP_008733119.1 1923986 D 1246995 CDS YP_008733120.1 556564695 17442443 1924592..1925437 1 NC_022657.1 COG0327 Uncharacterized conserved protein; hypothetical protein 1925437 17442443 AFR_08890 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733120.1 1924592 D 1246995 CDS YP_008733121.1 556564696 17442444 1925450..1926184 1 NC_022657.1 COG1579 Zn-ribbon protein, possibly nucleic acid-binding; hypothetical protein 1926184 17442444 AFR_08895 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733121.1 1925450 D 1246995 CDS YP_008733122.1 556564697 17442445 1926181..1927293 1 NC_022657.1 COG0328 Ribonuclease HI; bifunctional RNase H/acid phosphatase 1927293 17442445 AFR_08900 Actinoplanes friuliensis DSM 7358 bifunctional RNase H/acid phosphatase YP_008733122.1 1926181 D 1246995 CDS YP_008733123.1 556564698 17442446 1927394..1928683 1 NC_022657.1 COG3325 Chitinase; putative glycosyl hydrolase 1928683 17442446 AFR_08905 Actinoplanes friuliensis DSM 7358 putative glycosyl hydrolase YP_008733123.1 1927394 D 1246995 CDS YP_008733124.1 556564699 17442447 1928847..1929083 1 NC_022657.1 hypothetical protein 1929083 17442447 AFR_08910 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733124.1 1928847 D 1246995 CDS YP_008733125.1 556564700 17442448 1929076..1930722 1 NC_022657.1 COG0591 Na+/proline symporter; putative sodium:solute symporter 1930722 17442448 AFR_08915 Actinoplanes friuliensis DSM 7358 putative sodium:solute symporter YP_008733125.1 1929076 D 1246995 CDS YP_008733126.1 556564701 17442449 complement(1930791..1931252) 1 NC_022657.1 COG1846 Transcriptional regulators; regulatory protein MarR 1931252 17442449 AFR_08920 Actinoplanes friuliensis DSM 7358 regulatory protein MarR YP_008733126.1 1930791 R 1246995 CDS YP_008733127.1 556564702 17442450 complement(1931326..1932078) 1 NC_022657.1 COG0730 Predicted permeases; putative transmembrane protein 1932078 17442450 AFR_08925 Actinoplanes friuliensis DSM 7358 putative transmembrane protein YP_008733127.1 1931326 R 1246995 CDS YP_008733128.1 556564703 17442451 1932617..1932895 1 NC_022657.1 hypothetical protein 1932895 17442451 AFR_08930 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733128.1 1932617 D 1246995 CDS YP_008733129.1 556564704 17442452 1932920..1933159 1 NC_022657.1 hypothetical protein 1933159 17442452 AFR_08935 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733129.1 1932920 D 1246995 CDS YP_008733130.1 556564705 17442453 1933105..1933584 1 NC_022657.1 COG3339 Uncharacterized conserved protein; hypothetical protein 1933584 17442453 AFR_08940 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733130.1 1933105 D 1246995 CDS YP_008733131.1 556564706 17442454 complement(1933607..1933858) 1 NC_022657.1 COG0188 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit; hypothetical protein 1933858 17442454 AFR_08945 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733131.1 1933607 R 1246995 CDS YP_008733132.1 556564707 17442455 1933995..1934540 1 NC_022657.1 COG4278 Uncharacterized conserved protein; hypothetical protein 1934540 17442455 AFR_08950 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733132.1 1933995 D 1246995 CDS YP_008733133.1 556564708 17442456 1934742..1934954 1 NC_022657.1 COG0784 FOG: CheY-like receiver; hypothetical protein 1934954 17442456 AFR_08955 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733133.1 1934742 D 1246995 CDS YP_008733134.1 556564709 17442457 1934951..1936987 1 NC_022657.1 COG0642 Signal transduction histidine kinase; Sensor protein kinase walK 1936987 17442457 AFR_08960 Actinoplanes friuliensis DSM 7358 Sensor protein kinase walK YP_008733134.1 1934951 D 1246995 CDS YP_008733135.1 556564710 17442458 1937515..1938576 1 NC_022657.1 COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; putative glyceraldehyde 3-phosphate dehydrogenase 1938576 17442458 AFR_08965 Actinoplanes friuliensis DSM 7358 putative glyceraldehyde 3-phosphate dehydrogenase YP_008733135.1 1937515 D 1246995 CDS YP_008733136.1 556564711 17442459 1938587..1939501 1 NC_022657.1 COG1171 Threonine dehydratase; threonine dehydratase 1939501 17442459 AFR_08970 Actinoplanes friuliensis DSM 7358 threonine dehydratase YP_008733136.1 1938587 D 1246995 CDS YP_008733137.1 556564712 17442460 1939494..1940033 1 NC_022657.1 LinF 1940033 17442460 AFR_08975 Actinoplanes friuliensis DSM 7358 LinF YP_008733137.1 1939494 D 1246995 CDS YP_008733138.1 556564713 17442461 complement(1941599..1942819) 1 NC_022657.1 COG0477 Permeases of the major facilitator superfamily; putative MFS transporter 1942819 17442461 AFR_08980 Actinoplanes friuliensis DSM 7358 putative MFS transporter YP_008733138.1 1941599 R 1246995 CDS YP_008733139.1 556564714 17442462 1942901..1943812 1 NC_022657.1 COG0583 Transcriptional regulator; putative LysR-family transcriptional regulator 1943812 17442462 AFR_08985 Actinoplanes friuliensis DSM 7358 putative LysR-family transcriptional regulator YP_008733139.1 1942901 D 1246995 CDS YP_008733140.1 556564715 17442463 1943813..1944943 1 NC_022657.1 hypothetical protein 1944943 17442463 AFR_08990 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733140.1 1943813 D 1246995 CDS YP_008733141.1 556564716 17442464 1945049..1945663 1 NC_022657.1 COG0807 GTP cyclohydrolase II; putative GTP cyclohydrolase II 1945663 17442464 AFR_08995 Actinoplanes friuliensis DSM 7358 putative GTP cyclohydrolase II YP_008733141.1 1945049 D 1246995 CDS YP_008733142.1 556564717 17442465 1945754..1946362 1 NC_022657.1 COG1876 D-alanyl-D-alanine carboxypeptidase; putative D-alanyl-D-alanine carboxypeptidase 1946362 17442465 AFR_09000 Actinoplanes friuliensis DSM 7358 putative D-alanyl-D-alanine carboxypeptidase YP_008733142.1 1945754 D 1246995 CDS YP_008733143.1 556564718 17442466 complement(1946359..1947159) 1 NC_022657.1 COG0500 SAM-dependent methyltransferases; putative ubiquinone/menaquinone methyltransferase 1947159 17442466 AFR_09005 Actinoplanes friuliensis DSM 7358 putative ubiquinone/menaquinone methyltransferase YP_008733143.1 1946359 R 1246995 CDS YP_008733144.1 556564719 17442467 1947293..1948315 1 NC_022657.1 COG0136 Aspartate-semialdehyde dehydrogenase; aspartate-semialdehyde dehydrogenase 1948315 17442467 AFR_09010 Actinoplanes friuliensis DSM 7358 aspartate-semialdehyde dehydrogenase YP_008733144.1 1947293 D 1246995 CDS YP_008733145.1 556564720 17442468 complement(1948272..1950137) 1 NC_022657.1 hypothetical protein 1950137 17442468 AFR_09015 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733145.1 1948272 R 1246995 CDS YP_008733146.1 556564721 17442469 1950136..1950354 1 NC_022657.1 hypothetical protein 1950354 17442469 AFR_09020 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733146.1 1950136 D 1246995 CDS YP_008733147.1 556564722 17442470 1950434..1951882 1 NC_022657.1 COG0557 Exoribonuclease R; ribonuclease II 1951882 17442470 AFR_09025 Actinoplanes friuliensis DSM 7358 ribonuclease II YP_008733147.1 1950434 D 1246995 CDS YP_008733148.1 556564723 17442471 complement(1951920..1952369) 1 NC_022657.1 COG0346 Lactoylglutathione lyase and related lyases; glyoxalase/bleomycin resistance protein/dioxygenase 1952369 17442471 AFR_09030 Actinoplanes friuliensis DSM 7358 glyoxalase/bleomycin resistance protein/dioxygenase YP_008733148.1 1951920 R 1246995 CDS YP_008733149.1 556564724 17442472 complement(1952424..1953254) 1 NC_022657.1 COG0413 Ketopantoate hydroxymethyltransferase; 3-methyl-2-oxobutanoate hydroxymethyltransferase 1953254 17442472 AFR_09035 Actinoplanes friuliensis DSM 7358 3-methyl-2-oxobutanoate hydroxymethyltransferase YP_008733149.1 1952424 R 1246995 CDS YP_008733150.1 556564725 17442473 complement(1953353..1955116) 1 NC_022657.1 COG0388 Predicted amidohydrolase; putative NH3-dependent NAD+ synthetase 1955116 17442473 AFR_09040 Actinoplanes friuliensis DSM 7358 putative NH3-dependent NAD+ synthetase YP_008733150.1 1953353 R 1246995 CDS YP_008733151.1 556564726 17442474 1955283..1956635 1 NC_022657.1 COG0174 Glutamine synthetase; putative glutamine synthetase 1956635 17442474 AFR_09045 Actinoplanes friuliensis DSM 7358 putative glutamine synthetase YP_008733151.1 1955283 D 1246995 CDS YP_008733152.1 556564727 17442475 1956714..1957139 1 NC_022657.1 hypothetical protein 1957139 17442475 AFR_09050 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733152.1 1956714 D 1246995 CDS YP_008733153.1 556564728 17442476 complement(1957136..1958284) 1 NC_022657.1 COG4292 Predicted membrane protein; hypothetical protein 1958284 17442476 AFR_09055 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733153.1 1957136 R 1246995 CDS YP_008733154.1 556564729 17442477 1958398..1958883 1 NC_022657.1 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; GCN5-like N-acetyltransferase 1958883 17442477 AFR_09060 Actinoplanes friuliensis DSM 7358 GCN5-like N-acetyltransferase YP_008733154.1 1958398 D 1246995 CDS YP_008733155.1 556564730 17442478 1958893..1959678 1 NC_022657.1 COG0518 GMP synthase - Glutamine amidotransferase domain; putative glutamine amidotransferase 1959678 17442478 AFR_09065 Actinoplanes friuliensis DSM 7358 putative glutamine amidotransferase YP_008733155.1 1958893 D 1246995 CDS YP_008733156.1 556564731 17442479 1959679..1962714 1 NC_022657.1 COG1391 Glutamine synthetase adenylyltransferase; bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase 1962714 17442479 AFR_09070 Actinoplanes friuliensis DSM 7358 bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase YP_008733156.1 1959679 D 1246995 CDS YP_008733157.1 556564732 17442480 1962707..1964290 1 NC_022657.1 COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component; hypothetical protein 1964290 17442480 AFR_09075 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733157.1 1962707 D 1246995 CDS YP_008733158.1 556564733 17442481 1964290..1966245 1 NC_022657.1 hypothetical protein 1966245 17442481 AFR_09080 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733158.1 1964290 D 1246995 CDS YP_008733159.1 556564734 17442482 1966242..1967855 1 NC_022657.1 hypothetical protein 1967855 17442482 AFR_09085 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733159.1 1966242 D 1246995 CDS YP_008733160.1 556564735 17442483 1967852..1969594 1 NC_022657.1 hypothetical protein 1969594 17442483 AFR_09090 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733160.1 1967852 D 1246995 CDS YP_008733161.1 556564736 17442484 1969663..1971756 1 NC_022657.1 COG3391 Uncharacterized conserved protein; hypothetical protein 1971756 17442484 AFR_09095 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733161.1 1969663 D 1246995 CDS YP_008733162.1 556564737 17442485 complement(1971758..1974829) 1 NC_022657.1 COG3903 Predicted ATPase; Regulatory protein afsR 1974829 17442485 AFR_09100 Actinoplanes friuliensis DSM 7358 Regulatory protein afsR YP_008733162.1 1971758 R 1246995 CDS YP_008733163.1 556564738 17442486 1974914..1975543 1 NC_022657.1 COG1357 Uncharacterized low-complexity proteins; pentapeptide repeat-containing protein 1975543 17442486 AFR_09105 Actinoplanes friuliensis DSM 7358 pentapeptide repeat-containing protein YP_008733163.1 1974914 D 1246995 CDS YP_008733164.1 556564739 17442487 complement(1975544..1975969) 1 NC_022657.1 hypothetical protein 1975969 17442487 AFR_09110 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733164.1 1975544 R 1246995 CDS YP_008733165.1 556564740 17442488 1976217..1977641 1 NC_022657.1 COG0174 Glutamine synthetase; putative glutamine synthetase 1977641 17442488 AFR_09115 Actinoplanes friuliensis DSM 7358 putative glutamine synthetase YP_008733165.1 1976217 D 1246995 CDS YP_008733166.1 556564741 17442489 complement(1977723..1978823) 1 NC_022657.1 COG0582 Integrase; integrase family protein 1978823 17442489 AFR_09120 Actinoplanes friuliensis DSM 7358 integrase family protein YP_008733166.1 1977723 R 1246995 CDS YP_008733167.1 556564742 17442490 complement(1978915..1979136) 1 NC_022657.1 excisionase/Xis, DNA-binding protein 1979136 17442490 AFR_09125 Actinoplanes friuliensis DSM 7358 excisionase/Xis, DNA-binding protein YP_008733167.1 1978915 R 1246995 CDS YP_008733168.1 556564743 17442491 complement(1979208..1979693) 1 NC_022657.1 Replication initiator protein 1979693 17442491 AFR_09130 Actinoplanes friuliensis DSM 7358 Replication initiator protein YP_008733168.1 1979208 R 1246995 CDS YP_008733169.1 556564744 17442492 1979717..1980031 1 NC_022657.1 hypothetical protein 1980031 17442492 AFR_09135 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733169.1 1979717 D 1246995 CDS YP_008733170.1 556564745 17442493 1980028..1980360 1 NC_022657.1 hypothetical protein 1980360 17442493 AFR_09140 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733170.1 1980028 D 1246995 CDS YP_008733171.1 556564746 17442494 1980384..1981103 1 NC_022657.1 hypothetical protein 1981103 17442494 AFR_09145 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733171.1 1980384 D 1246995 CDS YP_008733172.1 556564747 17442495 1981525..1982229 1 NC_022657.1 hypothetical protein 1982229 17442495 AFR_09150 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733172.1 1981525 D 1246995 CDS YP_008733173.1 556564748 17442496 1983276..1985270 1 NC_022657.1 COG3903 Predicted ATPase; ATP/GTP binding protein 1985270 17442496 AFR_09155 Actinoplanes friuliensis DSM 7358 ATP/GTP binding protein YP_008733173.1 1983276 D 1246995 CDS YP_008733174.1 556564749 17442497 complement(1986113..1987711) 1 NC_022657.1 COG1479 Uncharacterized conserved protein; hypothetical protein 1987711 17442497 AFR_09160 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733174.1 1986113 R 1246995 CDS YP_008733175.1 556564750 17442498 1988424..1988747 1 NC_022657.1 COG1324 Uncharacterized protein involved in tolerance to divalent cations; protein involved in tolerance to divalent cations 1988747 17442498 AFR_09165 Actinoplanes friuliensis DSM 7358 protein involved in tolerance to divalent cations YP_008733175.1 1988424 D 1246995 CDS YP_008733176.1 556564751 17442499 1988808..1989326 1 NC_022657.1 COG0572 Uridine kinase; putative phosphoribulokinase/uridine kinase 1989326 17442499 AFR_09170 Actinoplanes friuliensis DSM 7358 putative phosphoribulokinase/uridine kinase YP_008733176.1 1988808 D 1246995 CDS YP_008733177.1 556564752 17442500 1989375..1989713 1 NC_022657.1 hypothetical protein 1989713 17442500 AFR_09175 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733177.1 1989375 D 1246995 CDS YP_008733178.1 556564753 17442501 1989742..1990083 1 NC_022657.1 hypothetical protein 1990083 17442501 AFR_09180 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733178.1 1989742 D 1246995 CDS YP_008733179.1 556564754 17442502 complement(1990087..1990536) 1 NC_022657.1 hypothetical protein 1990536 17442502 AFR_09185 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733179.1 1990087 R 1246995 CDS YP_008733180.1 556564755 17442503 complement(1990673..1991365) 1 NC_022657.1 hypothetical protein 1991365 17442503 AFR_09190 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733180.1 1990673 R 1246995 CDS YP_008733181.1 556564756 17442504 complement(1991383..1992006) 1 NC_022657.1 hypothetical protein 1992006 17442504 AFR_09195 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733181.1 1991383 R 1246995 CDS YP_008733182.1 556564757 17442505 1992147..1992470 1 NC_022657.1 COG3795 Uncharacterized protein conserved in bacteria; DGPFAETKE family protein 1992470 17442505 AFR_09200 Actinoplanes friuliensis DSM 7358 DGPFAETKE family protein YP_008733182.1 1992147 D 1246995 CDS YP_008733183.1 556564758 17442506 1992511..1994481 1 NC_022657.1 COG4941 Predicted RNA polymerase sigma factor containing a TPR repeat domain; RNA polymerase sigma factor containing a TPR repeat domain-like protein 1994481 17442506 AFR_09205 Actinoplanes friuliensis DSM 7358 RNA polymerase sigma factor containing a TPR repeat domain-like protein YP_008733183.1 1992511 D 1246995 CDS YP_008733184.1 556564759 17442507 complement(1994453..1995385) 1 NC_022657.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); hypothetical protein 1995385 17442507 AFR_09210 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733184.1 1994453 R 1246995 CDS YP_008733185.1 556564760 17442508 complement(1995469..1996056) 1 NC_022657.1 COG1309 Transcriptional regulator; TetR family transcriptional regulator 1996056 17442508 AFR_09215 Actinoplanes friuliensis DSM 7358 TetR family transcriptional regulator YP_008733185.1 1995469 R 1246995 CDS YP_008733186.1 556564761 17442509 1996148..1996594 1 NC_022657.1 hypothetical protein 1996594 17442509 AFR_09220 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733186.1 1996148 D 1246995 CDS YP_008733187.1 556564762 17442510 complement(1996671..1997594) 1 NC_022657.1 COG0320 Lipoate synthase; lipoyl synthase 1997594 17442510 AFR_09225 Actinoplanes friuliensis DSM 7358 lipoyl synthase YP_008733187.1 1996671 R 1246995 CDS YP_008733188.1 556564763 17442511 1997952..1999208 1 NC_022657.1 COG0017 Aspartyl/asparaginyl-tRNA synthetases; aspartyl-tRNA ligase 1999208 aspC 17442511 aspC Actinoplanes friuliensis DSM 7358 aspartyl-tRNA ligase YP_008733188.1 1997952 D 1246995 CDS YP_008733189.1 556564764 17442512 complement(1999210..1999374) 1 NC_022657.1 COG4194 Predicted membrane protein; hypothetical protein 1999374 17442512 AFR_09235 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733189.1 1999210 R 1246995 CDS YP_008733190.1 556564765 17442513 complement(1999371..2000006) 1 NC_022657.1 COG0321 Lipoate-protein ligase B; lipoyl(octanoyl) transferase 2000006 17442513 AFR_09240 Actinoplanes friuliensis DSM 7358 lipoyl(octanoyl) transferase YP_008733190.1 1999371 R 1246995 CDS YP_008733191.1 556564766 17442514 complement(2000011..2001873) 1 NC_022657.1 hypothetical protein 2001873 17442514 AFR_09245 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733191.1 2000011 R 1246995 CDS YP_008733192.1 556564767 17442515 complement(2001905..2002822) 1 NC_022657.1 COG1090 Predicted nucleoside-diphosphate sugar epimerase; hypothetical protein 2002822 17442515 AFR_09250 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733192.1 2001905 R 1246995 CDS YP_008733193.1 556564768 17442516 complement(2002903..2004747) 1 NC_022657.1 COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes; putative dihydrolipoamide S-succinyltransferase 2004747 17442516 AFR_09255 Actinoplanes friuliensis DSM 7358 putative dihydrolipoamide S-succinyltransferase YP_008733193.1 2002903 R 1246995 CDS YP_008733194.1 556564769 17442517 complement(2004788..2006173) 1 NC_022657.1 COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes; dihydrolipoamide dehydrogenase 2006173 17442517 AFR_09260 Actinoplanes friuliensis DSM 7358 dihydrolipoamide dehydrogenase YP_008733194.1 2004788 R 1246995 CDS YP_008733195.1 556564770 17442518 2006335..2006655 1 NC_022657.1 hypothetical protein 2006655 17442518 AFR_09265 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733195.1 2006335 D 1246995 CDS YP_008733196.1 556564771 17442519 complement(2006677..2008227) 1 NC_022657.1 COG0260 Leucyl aminopeptidase; leucyl aminopeptidase 2008227 17442519 AFR_09270 Actinoplanes friuliensis DSM 7358 leucyl aminopeptidase YP_008733196.1 2006677 R 1246995 CDS YP_008733197.1 556564772 17442520 2008371..2009471 1 NC_022657.1 COG0404 Glycine cleavage system T protein (aminomethyltransferase); glycine cleavage system aminomethyltransferase T 2009471 gcvT 17442520 gcvT Actinoplanes friuliensis DSM 7358 glycine cleavage system aminomethyltransferase T YP_008733197.1 2008371 D 1246995 CDS YP_008733198.1 556564773 17442521 complement(2009468..2010190) 1 NC_022657.1 COG0368 Cobalamin-5-phosphate synthase; putative cobalamin 5'-phosphate synthase 2010190 17442521 AFR_09280 Actinoplanes friuliensis DSM 7358 putative cobalamin 5'-phosphate synthase YP_008733198.1 2009468 R 1246995 CDS YP_008733199.1 556564774 17442522 complement(2010183..2012039) 1 NC_022657.1 COG2087 Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase; putative cobalamin biosynthesis protein 2012039 17442522 AFR_09285 Actinoplanes friuliensis DSM 7358 putative cobalamin biosynthesis protein YP_008733199.1 2010183 R 1246995 CDS YP_008733200.1 556564775 17442523 2012208..2012405 1 NC_022657.1 hypothetical protein 2012405 17442523 AFR_09290 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733200.1 2012208 D 1246995 CDS YP_008733201.1 556564776 17442524 2012402..2013229 1 NC_022657.1 COG1994 Zn-dependent proteases; putative M50-family peptidase 2013229 17442524 AFR_09295 Actinoplanes friuliensis DSM 7358 putative M50-family peptidase YP_008733201.1 2012402 D 1246995 CDS YP_008733202.1 556564777 17442525 complement(2013266..2014264) 1 NC_022657.1 COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases); aldo/keto reductase 2014264 17442525 AFR_09300 Actinoplanes friuliensis DSM 7358 aldo/keto reductase YP_008733202.1 2013266 R 1246995 CDS YP_008733203.1 556564778 17442526 complement(2014285..2017104) 1 NC_022657.1 COG0457 FOG: TPR repeat; Aggrecan core protein 2017104 17442526 AFR_09305 Actinoplanes friuliensis DSM 7358 Aggrecan core protein YP_008733203.1 2014285 R 1246995 CDS YP_008733204.1 556564779 17442527 2019935..2020795 1 NC_022657.1 COG4587 ABC-type uncharacterized transport system, permease component; hypothetical protein 2020795 17442527 AFR_09310 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733204.1 2019935 D 1246995 CDS YP_008733205.1 556564780 17442528 2020788..2021588 1 NC_022657.1 COG3694 ABC-type uncharacterized transport system, permease component; hypothetical protein 2021588 17442528 AFR_09315 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733205.1 2020788 D 1246995 CDS YP_008733206.1 556564781 17442529 2021585..2022538 1 NC_022657.1 COG4586 ABC-type uncharacterized transport system, ATPase component; putative ABC transporter ATP-binding protein 2022538 17442529 AFR_09320 Actinoplanes friuliensis DSM 7358 putative ABC transporter ATP-binding protein YP_008733206.1 2021585 D 1246995 CDS YP_008733207.1 556564782 17442530 complement(2022535..2023146) 1 NC_022657.1 COG1396 Predicted transcriptional regulators; putative transcriptional regulator 2023146 17442530 AFR_09325 Actinoplanes friuliensis DSM 7358 putative transcriptional regulator YP_008733207.1 2022535 R 1246995 CDS YP_008733208.1 556564783 17442531 2023158..2023889 1 NC_022657.1 COG1296 Predicted branched-chain amino acid permease (azaleucine resistance); hypothetical protein 2023889 17442531 AFR_09330 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733208.1 2023158 D 1246995 CDS YP_008733209.1 556564784 17442532 2023883..2024191 1 NC_022657.1 branched-chain amino acid transport 2024191 17442532 AFR_09335 Actinoplanes friuliensis DSM 7358 branched-chain amino acid transport YP_008733209.1 2023883 D 1246995 CDS YP_008733210.1 556564785 17442533 complement(2025517..2026152) 1 NC_022657.1 hypothetical protein 2026152 17442533 AFR_09340 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733210.1 2025517 R 1246995 CDS YP_008733211.1 556564786 17442534 complement(2026230..2027585) 1 NC_022657.1 COG0766 UDP-N-acetylglucosamine enolpyruvyl transferase; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 2027585 17442534 AFR_09345 Actinoplanes friuliensis DSM 7358 UDP-N-acetylglucosamine 1-carboxyvinyltransferase YP_008733211.1 2026230 R 1246995 CDS YP_008733212.1 556564787 17442535 complement(2027802..2028971) 1 NC_022657.1 COG0379 Quinolinate synthase; quinolinate synthetase 2028971 17442535 AFR_09350 Actinoplanes friuliensis DSM 7358 quinolinate synthetase YP_008733212.1 2027802 R 1246995 CDS YP_008733213.1 556564788 17442536 complement(2029032..2029181) 1 NC_022657.1 hypothetical protein 2029181 17442536 AFR_09355 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733213.1 2029032 R 1246995 CDS YP_008733214.1 556564789 17442537 2029206..2030342 1 NC_022657.1 COG1929 Glycerate kinase; putative glycerate kinase 2030342 17442537 AFR_09360 Actinoplanes friuliensis DSM 7358 putative glycerate kinase YP_008733214.1 2029206 D 1246995 CDS YP_008733215.1 556564790 17442538 2030445..2030819 1 NC_022657.1 COG0316 Uncharacterized conserved protein; Putative iron-sulfur cluster insertion protein erpA 2030819 17442538 AFR_09365 Actinoplanes friuliensis DSM 7358 Putative iron-sulfur cluster insertion protein erpA YP_008733215.1 2030445 D 1246995 CDS YP_008733216.1 556564791 17442539 2030952..2031935 1 NC_022657.1 COG0524 Sugar kinases, ribokinase family; putative PfkB-family carbohydrate kinase 2031935 17442539 AFR_09370 Actinoplanes friuliensis DSM 7358 putative PfkB-family carbohydrate kinase YP_008733216.1 2030952 D 1246995 CDS YP_008733217.1 556564792 17442540 2031941..2032453 1 NC_022657.1 COG0645 Predicted kinase; hypothetical protein 2032453 17442540 AFR_09375 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733217.1 2031941 D 1246995 CDS YP_008733218.1 556564793 17442541 complement(2032429..2032641) 1 NC_022657.1 COG0425 Predicted redox protein, regulator of disulfide bond formation; putative SirA-like protein 2032641 17442541 AFR_09380 Actinoplanes friuliensis DSM 7358 putative SirA-like protein YP_008733218.1 2032429 R 1246995 CDS YP_008733219.1 556564794 17442542 complement(2032638..2033783) 1 NC_022657.1 COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes; cysteine desulfurase 2033783 17442542 AFR_09385 Actinoplanes friuliensis DSM 7358 cysteine desulfurase YP_008733219.1 2032638 R 1246995 CDS YP_008733220.1 556564795 17442543 2033954..2034889 1 NC_022657.1 COG1622 Heme/copper-type cytochrome/quinol oxidases, subunit 2; putative cytochrome c oxidase subunit II 2034889 17442543 AFR_09390 Actinoplanes friuliensis DSM 7358 putative cytochrome c oxidase subunit II YP_008733220.1 2033954 D 1246995 CDS YP_008733221.1 556564796 17442544 2034899..2035324 1 NC_022657.1 cytochrome-c oxidase 2035324 17442544 AFR_09395 Actinoplanes friuliensis DSM 7358 cytochrome-c oxidase YP_008733221.1 2034899 D 1246995 CDS YP_008733222.1 556564797 17442545 complement(2035406..2035597) 1 NC_022657.1 hypothetical protein 2035597 17442545 AFR_09400 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733222.1 2035406 R 1246995 CDS YP_008733223.1 556564798 17442546 complement(2035724..2036788) 1 NC_022657.1 COG0547 Anthranilate phosphoribosyltransferase; anthranilate phosphoribosyltransferase 2036788 trpD 17442546 trpD Actinoplanes friuliensis DSM 7358 anthranilate phosphoribosyltransferase YP_008733223.1 2035724 R 1246995 CDS YP_008733224.1 556564799 17442547 complement(2036837..2037280) 1 NC_022657.1 transcriptional regulatory protein ompR 2037280 17442547 AFR_09410 Actinoplanes friuliensis DSM 7358 transcriptional regulatory protein ompR YP_008733224.1 2036837 R 1246995 CDS YP_008733225.1 556564800 17442548 complement(2037332..2038300) 1 NC_022657.1 COG3336 Predicted membrane protein; hypothetical protein 2038300 17442548 AFR_09415 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733225.1 2037332 R 1246995 CDS YP_008733226.1 556564801 17442549 2038425..2039021 1 NC_022657.1 COG1845 Heme/copper-type cytochrome/quinol oxidase, subunit 3; putative cytochrome c oxidase subunit III 2039021 17442549 AFR_09420 Actinoplanes friuliensis DSM 7358 putative cytochrome c oxidase subunit III YP_008733226.1 2038425 D 1246995 CDS YP_008733227.1 556564802 17442550 2039071..2039919 1 NC_022657.1 COG2010 Cytochrome c, mono- and diheme variants; putative cytochrome c heme-binding subunit 2039919 17442550 AFR_09425 Actinoplanes friuliensis DSM 7358 putative cytochrome c heme-binding subunit YP_008733227.1 2039071 D 1246995 CDS YP_008733228.1 556564803 17442551 2039916..2041019 1 NC_022657.1 COG0723 Rieske Fe-S protein; putative menaquinol-cytochrome c reductase iron-sulfur subunit 2041019 17442551 AFR_09430 Actinoplanes friuliensis DSM 7358 putative menaquinol-cytochrome c reductase iron-sulfur subunit YP_008733228.1 2039916 D 1246995 CDS YP_008733229.1 556564804 17442552 2041016..2042641 1 NC_022657.1 COG1290 Cytochrome b subunit of the bc complex; ubiquinol-cytochrome c reductase cytochrome b subunit 2042641 17442552 AFR_09435 Actinoplanes friuliensis DSM 7358 ubiquinol-cytochrome c reductase cytochrome b subunit YP_008733229.1 2041016 D 1246995 CDS YP_008733230.1 556564805 17442553 complement(2042713..2043000) 1 NC_022657.1 COG1522 Transcriptional regulators; Leucine-responsive regulatory protein 2043000 17442553 AFR_09440 Actinoplanes friuliensis DSM 7358 Leucine-responsive regulatory protein YP_008733230.1 2042713 R 1246995 CDS YP_008733231.1 556564806 17442554 complement(2043084..2043626) 1 NC_022657.1 COG1695 Predicted transcriptional regulators; PadR family transcriptional regulator 2043626 17442554 AFR_09445 Actinoplanes friuliensis DSM 7358 PadR family transcriptional regulator YP_008733231.1 2043084 R 1246995 CDS YP_008733232.1 556564807 17442555 2043710..2044249 1 NC_022657.1 hypothetical protein 2044249 17442555 AFR_09450 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733232.1 2043710 D 1246995 CDS YP_008733233.1 556564808 17442556 complement(2045048..2045878) 1 NC_022657.1 COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon); putative nucleotidyltransferase 2045878 17442556 AFR_09455 Actinoplanes friuliensis DSM 7358 putative nucleotidyltransferase YP_008733233.1 2045048 R 1246995 CDS YP_008733234.1 556564809 17442557 complement(2045875..2046360) 1 NC_022657.1 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; NUDIX hydrolase 2046360 17442557 AFR_09460 Actinoplanes friuliensis DSM 7358 NUDIX hydrolase YP_008733234.1 2045875 R 1246995 CDS YP_008733235.1 556564810 17442558 complement(2046410..2048119) 1 NC_022657.1 COG0317 Guanosine polyphosphate pyrophosphohydrolases/synthetases; putative ppGpp synthetase 2048119 17442558 AFR_09465 Actinoplanes friuliensis DSM 7358 putative ppGpp synthetase YP_008733235.1 2046410 R 1246995 CDS YP_008733236.1 556564811 17442559 complement(2048292..2050073) 1 NC_022657.1 COG0847 DNA polymerase III, epsilon subunit and related 3'-5' exonucleases; hypothetical protein 2050073 17442559 AFR_09470 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733236.1 2048292 R 1246995 CDS YP_008733237.1 556564812 17442560 2050196..2051674 1 NC_022657.1 COG3688 Predicted RNA-binding protein containing a PIN domain; hypothetical protein 2051674 17442560 AFR_09475 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733237.1 2050196 D 1246995 CDS YP_008733238.1 556564813 17442561 2051782..2052003 1 NC_022657.1 hypothetical protein 2052003 17442561 AFR_09480 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733238.1 2051782 D 1246995 CDS YP_008733239.1 556564814 17442562 2052047..2053303 1 NC_022657.1 COG0501 Zn-dependent protease with chaperone function; Ste24 endopeptidase 2053303 17442562 AFR_09485 Actinoplanes friuliensis DSM 7358 Ste24 endopeptidase YP_008733239.1 2052047 D 1246995 CDS YP_008733240.1 556564815 17442563 2053303..2054430 1 NC_022657.1 COG0438 Glycosyltransferase; phosphatidylinositol alpha-1, 6-mannosyltransferase 2054430 17442563 AFR_09490 Actinoplanes friuliensis DSM 7358 phosphatidylinositol alpha-1, 6-mannosyltransferase YP_008733240.1 2053303 D 1246995 CDS YP_008733241.1 556564816 17442564 2054557..2056446 1 NC_022657.1 COG1132 ABC-type multidrug transport system, ATPase and permease components; putative ABC transporter ATP-binding protein 2056446 17442564 AFR_09495 Actinoplanes friuliensis DSM 7358 putative ABC transporter ATP-binding protein YP_008733241.1 2054557 D 1246995 CDS YP_008733242.1 556564817 17442565 2056488..2057048 1 NC_022657.1 COG0526 Thiol-disulfide isomerase and thioredoxins; putative thioredoxin 2057048 17442565 AFR_09500 Actinoplanes friuliensis DSM 7358 putative thioredoxin YP_008733242.1 2056488 D 1246995 CDS YP_008733243.1 556564818 17442566 2057191..2057703 1 NC_022657.1 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; RNA polymerase sigma-E factor 2057703 17442566 AFR_09505 Actinoplanes friuliensis DSM 7358 RNA polymerase sigma-E factor YP_008733243.1 2057191 D 1246995 CDS YP_008733244.1 556564819 17442567 2057700..2058503 1 NC_022657.1 hypothetical protein 2058503 17442567 AFR_09510 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733244.1 2057700 D 1246995 CDS YP_008733245.1 556564820 17442568 2058535..2059335 1 NC_022657.1 COG1131 ABC-type multidrug transport system, ATPase component; putative ABC transporter ATP-binding protein 2059335 17442568 AFR_09515 Actinoplanes friuliensis DSM 7358 putative ABC transporter ATP-binding protein YP_008733245.1 2058535 D 1246995 CDS YP_008733246.1 556564821 17442569 2059332..2060654 1 NC_022657.1 hypothetical protein 2060654 17442569 AFR_09520 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733246.1 2059332 D 1246995 CDS YP_008733247.1 556564822 17442570 2060651..2061253 1 NC_022657.1 hypothetical protein 2061253 17442570 AFR_09525 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733247.1 2060651 D 1246995 CDS YP_008733248.1 556564823 17442571 2061329..2061742 1 NC_022657.1 hypothetical protein 2061742 17442571 AFR_09530 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733248.1 2061329 D 1246995 CDS YP_008733249.1 556564824 17442572 complement(2061891..2062559) 1 NC_022657.1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; transcriptional regulatory protein degU 2062559 17442572 AFR_09535 Actinoplanes friuliensis DSM 7358 transcriptional regulatory protein degU YP_008733249.1 2061891 R 1246995 CDS YP_008733250.1 556564825 17442573 complement(2062567..2064195) 1 NC_022657.1 COG4585 Signal transduction histidine kinase; putative two-component system sensor kinase 2064195 17442573 AFR_09540 Actinoplanes friuliensis DSM 7358 putative two-component system sensor kinase YP_008733250.1 2062567 R 1246995 CDS YP_008733251.1 556564826 17442574 2064466..2064918 1 NC_022657.1 putative cyclase/dehydrase 2064918 17442574 AFR_09545 Actinoplanes friuliensis DSM 7358 putative cyclase/dehydrase YP_008733251.1 2064466 D 1246995 CDS YP_008733252.1 556564827 17442575 2065831..2067123 1 NC_022657.1 triple helix repeat-containing collagen 2067123 17442575 AFR_09550 Actinoplanes friuliensis DSM 7358 triple helix repeat-containing collagen YP_008733252.1 2065831 D 1246995 CDS YP_008733253.1 556564828 17442576 2067146..2068096 1 NC_022657.1 COG1940 Transcriptional regulator/sugar kinase; putative sugar kinase 2068096 17442576 AFR_09555 Actinoplanes friuliensis DSM 7358 putative sugar kinase YP_008733253.1 2067146 D 1246995 CDS YP_008733254.1 556564829 17442577 2068127..2068813 1 NC_022657.1 COG0708 Exonuclease III; hypothetical protein 2068813 17442577 AFR_09560 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733254.1 2068127 D 1246995 CDS YP_008733255.1 556564830 17442578 2068839..2070185 1 NC_022657.1 COG2072 Predicted flavoprotein involved in K+ transport; putative monooxygenase 2070185 17442578 AFR_09565 Actinoplanes friuliensis DSM 7358 putative monooxygenase YP_008733255.1 2068839 D 1246995 CDS YP_008733256.1 556564831 17442579 2070182..2070961 1 NC_022657.1 COG2267 Lysophospholipase; alpha/beta hydrolase fold protein 2070961 17442579 AFR_09570 Actinoplanes friuliensis DSM 7358 alpha/beta hydrolase fold protein YP_008733256.1 2070182 D 1246995 CDS YP_008733257.1 556564832 17442580 complement(2070950..2072362) 1 NC_022657.1 COG0380 Trehalose-6-phosphate synthase; alpha,alpha-trehalose-phosphate synthase (UDP-forming) 2072362 17442580 AFR_09575 Actinoplanes friuliensis DSM 7358 alpha,alpha-trehalose-phosphate synthase (UDP-forming) YP_008733257.1 2070950 R 1246995 CDS YP_008733258.1 556564833 17442581 complement(2072422..2073189) 1 NC_022657.1 hypothetical protein 2073189 17442581 AFR_09580 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733258.1 2072422 R 1246995 CDS YP_008733259.1 556564834 17442582 2073445..2074197 1 NC_022657.1 COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase; 1-acyl-sn-glycerol-3-phosphate acyltransferase 2074197 17442582 AFR_09585 Actinoplanes friuliensis DSM 7358 1-acyl-sn-glycerol-3-phosphate acyltransferase YP_008733259.1 2073445 D 1246995 CDS YP_008733260.1 556564835 17442583 complement(2074349..2075041) 1 NC_022657.1 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases; Anaerobic regulatory protein 2075041 17442583 AFR_09590 Actinoplanes friuliensis DSM 7358 Anaerobic regulatory protein YP_008733260.1 2074349 R 1246995 CDS YP_008733261.1 556564836 17442584 2075274..2076155 1 NC_022657.1 COG2334 Putative homoserine kinase type II (protein kinase fold); Homoserine kinase 2076155 17442584 AFR_09595 Actinoplanes friuliensis DSM 7358 Homoserine kinase YP_008733261.1 2075274 D 1246995 CDS YP_008733262.1 556564837 17442585 2076172..2076666 1 NC_022657.1 hypothetical protein 2076666 17442585 AFR_09600 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733262.1 2076172 D 1246995 CDS YP_008733263.1 556564838 17442586 2076966..2077202 1 NC_022657.1 hypothetical protein 2077202 17442586 AFR_09605 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733263.1 2076966 D 1246995 CDS YP_008733264.1 556564839 17442587 complement(2077204..2078085) 1 NC_022657.1 COG0451 Nucleoside-diphosphate-sugar epimerases; NAD-dependent epimerase/dehydratase 2078085 17442587 AFR_09610 Actinoplanes friuliensis DSM 7358 NAD-dependent epimerase/dehydratase YP_008733264.1 2077204 R 1246995 CDS YP_008733265.1 556564840 17442588 2078172..2078750 1 NC_022657.1 COG1309 Transcriptional regulator; TetR family transcriptional regulator 2078750 17442588 AFR_09615 Actinoplanes friuliensis DSM 7358 TetR family transcriptional regulator YP_008733265.1 2078172 D 1246995 CDS YP_008733266.1 556564841 17442589 2079059..2079673 1 NC_022657.1 COG3871 Uncharacterized stress protein (general stress protein 26); putative pyridoxamine 5'-phosphate oxidase-related protein 2079673 17442589 AFR_09620 Actinoplanes friuliensis DSM 7358 putative pyridoxamine 5'-phosphate oxidase-related protein YP_008733266.1 2079059 D 1246995 CDS YP_008733267.1 556564842 17442590 2079812..2080840 1 NC_022657.1 COG0205 6-phosphofructokinase; 6-phosphofructokinase 2080840 17442590 AFR_09625 Actinoplanes friuliensis DSM 7358 6-phosphofructokinase YP_008733267.1 2079812 D 1246995 CDS YP_008733268.1 556564843 17442591 2080889..2081692 1 NC_022657.1 COG0345 Pyrroline-5-carboxylate reductase; pyrroline-5-carboxylate reductase 2081692 17442591 AFR_09630 Actinoplanes friuliensis DSM 7358 pyrroline-5-carboxylate reductase YP_008733268.1 2080889 D 1246995 CDS YP_008733269.1 556564844 17442592 complement(2081689..2082354) 1 NC_022657.1 COG4923 Uncharacterized conserved protein; hypothetical protein 2082354 17442592 AFR_09635 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733269.1 2081689 R 1246995 CDS YP_008733270.1 556564845 17442593 complement(2082374..2082793) 1 NC_022657.1 COG0386 Glutathione peroxidase; glutathione peroxidase 2082793 17442593 AFR_09640 Actinoplanes friuliensis DSM 7358 glutathione peroxidase YP_008733270.1 2082374 R 1246995 CDS YP_008733271.1 556564846 17442594 2083017..2084489 1 NC_022657.1 COG3979 Uncharacterized protein contain chitin-binding domain type 3; chitinase 2084489 17442594 AFR_09645 Actinoplanes friuliensis DSM 7358 chitinase YP_008733271.1 2083017 D 1246995 CDS YP_008733272.1 556564847 17442595 2084560..2085966 1 NC_022657.1 COG3200 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase; phospho-2-dehydro-3-deoxyheptonate aldolase 2085966 17442595 AFR_09650 Actinoplanes friuliensis DSM 7358 phospho-2-dehydro-3-deoxyheptonate aldolase YP_008733272.1 2084560 D 1246995 CDS YP_008733273.1 556564848 17442596 2085959..2086978 1 NC_022657.1 COG2008 Threonine aldolase; threonine aldolase 2086978 17442596 AFR_09655 Actinoplanes friuliensis DSM 7358 threonine aldolase YP_008733273.1 2085959 D 1246995 CDS YP_008733274.1 556564849 17442597 complement(2087954..2088523) 1 NC_022657.1 COG1309 Transcriptional regulator; TetR family transcriptional regulator 2088523 17442597 AFR_09660 Actinoplanes friuliensis DSM 7358 TetR family transcriptional regulator YP_008733274.1 2087954 R 1246995 CDS YP_008733275.1 556564850 17442598 2088579..2089523 1 NC_022657.1 COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases; molecular chaperone GroES 2089523 17442598 AFR_09665 Actinoplanes friuliensis DSM 7358 molecular chaperone GroES YP_008733275.1 2088579 D 1246995 CDS YP_008733276.1 556564851 17442599 2089516..2089899 1 NC_022657.1 hypothetical protein 2089899 17442599 AFR_09670 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733276.1 2089516 D 1246995 CDS YP_008733277.1 556564852 17442600 complement(2089896..2090813) 1 NC_022657.1 COG1396 Predicted transcriptional regulators; hypothetical protein 2090813 17442600 AFR_09675 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733277.1 2089896 R 1246995 CDS YP_008733278.1 556564853 17442601 2090914..2091804 1 NC_022657.1 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases; hypothetical protein 2091804 17442601 AFR_09680 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733278.1 2090914 D 1246995 CDS YP_008733279.1 556564854 17442602 complement(2091782..2092645) 1 NC_022657.1 COG0648 Endonuclease IV; apurinic endonuclease Apn1 2092645 17442602 AFR_09685 Actinoplanes friuliensis DSM 7358 apurinic endonuclease Apn1 YP_008733279.1 2091782 R 1246995 CDS YP_008733280.1 556564855 17442603 complement(2092636..2094615) 1 NC_022657.1 COG0515 Serine/threonine protein kinase; putative serine/threonine protein kinase 2094615 17442603 AFR_09690 Actinoplanes friuliensis DSM 7358 putative serine/threonine protein kinase YP_008733280.1 2092636 R 1246995 CDS YP_008733281.1 556564856 17442604 complement(2094768..2095553) 1 NC_022657.1 Major cell-surface adhesin PAc 2095553 17442604 AFR_09695 Actinoplanes friuliensis DSM 7358 Major cell-surface adhesin PAc YP_008733281.1 2094768 R 1246995 CDS YP_008733282.1 556564857 17442605 2095647..2096024 1 NC_022657.1 hypothetical protein 2096024 17442605 AFR_09700 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733282.1 2095647 D 1246995 CDS YP_008733283.1 556564858 17442606 2096032..2096358 1 NC_022657.1 hypothetical protein 2096358 17442606 AFR_09705 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733283.1 2096032 D 1246995 CDS YP_008733284.1 556564859 17442607 2096355..2096723 1 NC_022657.1 hypothetical protein 2096723 17442607 AFR_09710 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733284.1 2096355 D 1246995 CDS YP_008733285.1 556564860 17442608 2096736..2097704 1 NC_022657.1 hypothetical protein 2097704 17442608 AFR_09715 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733285.1 2096736 D 1246995 CDS YP_008733286.1 556564861 17442609 complement(2097839..2098906) 1 NC_022657.1 COG0142 Geranylgeranyl pyrophosphate synthase; polyprenyl synthetase 2098906 17442609 AFR_09720 Actinoplanes friuliensis DSM 7358 polyprenyl synthetase YP_008733286.1 2097839 R 1246995 CDS YP_008733287.1 556564862 17442610 2098946..2099860 1 NC_022657.1 COG0685 5,10-methylenetetrahydrofolate reductase; putative 5,10-methylenetetrahydrofolate reductase 2099860 17442610 AFR_09725 Actinoplanes friuliensis DSM 7358 putative 5,10-methylenetetrahydrofolate reductase YP_008733287.1 2098946 D 1246995 CDS YP_008733288.1 556564863 17442611 2099857..2100525 1 NC_022657.1 COG0558 Phosphatidylglycerophosphate synthase; CDP-alcohol phosphatidyltransferase 2100525 17442611 AFR_09730 Actinoplanes friuliensis DSM 7358 CDP-alcohol phosphatidyltransferase YP_008733288.1 2099857 D 1246995 CDS YP_008733289.1 556564864 17442612 2100748..2101191 1 NC_022657.1 COG1403 Restriction endonuclease; HNH endonuclease 2101191 17442612 AFR_09735 Actinoplanes friuliensis DSM 7358 HNH endonuclease YP_008733289.1 2100748 D 1246995 CDS YP_008733290.1 556564865 17442613 complement(2101249..2102451) 1 NC_022657.1 COG0847 DNA polymerase III, epsilon subunit and related 3'-5' exonucleases; DNA polymerase III subunit epsilon 2102451 17442613 AFR_09740 Actinoplanes friuliensis DSM 7358 DNA polymerase III subunit epsilon YP_008733290.1 2101249 R 1246995 CDS YP_008733291.1 556564866 17442614 2102669..2103166 1 NC_022657.1 COG1846 Transcriptional regulators; putative MarR-family transcriptional regulator 2103166 17442614 AFR_09745 Actinoplanes friuliensis DSM 7358 putative MarR-family transcriptional regulator YP_008733291.1 2102669 D 1246995 CDS YP_008733292.1 556564867 17442615 2103256..2104731 1 NC_022657.1 COG0477 Permeases of the major facilitator superfamily; major facilitator transporter 2104731 17442615 AFR_09750 Actinoplanes friuliensis DSM 7358 major facilitator transporter YP_008733292.1 2103256 D 1246995 CDS YP_008733293.1 556564868 17442616 2104873..2105352 1 NC_022657.1 hypothetical protein 2105352 17442616 AFR_09755 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733293.1 2104873 D 1246995 CDS YP_008733294.1 556564869 17442617 2105430..2106587 1 NC_022657.1 COG0477 Permeases of the major facilitator superfamily; major facilitator superfamily protein 2106587 17442617 AFR_09760 Actinoplanes friuliensis DSM 7358 major facilitator superfamily protein YP_008733294.1 2105430 D 1246995 CDS YP_008733295.1 556564870 17442618 complement(2106553..2107992) 1 NC_022657.1 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases; FAD-binding monooxygenase 2107992 17442618 AFR_09765 Actinoplanes friuliensis DSM 7358 FAD-binding monooxygenase YP_008733295.1 2106553 R 1246995 CDS YP_008733296.1 556564871 17442619 2108097..2108714 1 NC_022657.1 COG1309 Transcriptional regulator; TetR family transcriptional regulator 2108714 17442619 AFR_09770 Actinoplanes friuliensis DSM 7358 TetR family transcriptional regulator YP_008733296.1 2108097 D 1246995 CDS YP_008733297.1 556564872 17442620 complement(2108722..2109291) 1 NC_022657.1 COG4300 Predicted permease, cadmium resistance protein; cadmium resistance transporter 2109291 17442620 AFR_09775 Actinoplanes friuliensis DSM 7358 cadmium resistance transporter YP_008733297.1 2108722 R 1246995 CDS YP_008733298.1 556564873 17442621 complement(2109295..2109852) 1 NC_022657.1 COG0572 Uridine kinase; uridine kinase 2109852 17442621 AFR_09780 Actinoplanes friuliensis DSM 7358 uridine kinase YP_008733298.1 2109295 R 1246995 CDS YP_008733299.1 556564874 17442622 complement(2109911..2110324) 1 NC_022657.1 pyridoxamine 5'-phosphate oxidase-related FMN- binding protein 2110324 17442622 AFR_09785 Actinoplanes friuliensis DSM 7358 pyridoxamine 5'-phosphate oxidase-related FMN- binding protein YP_008733299.1 2109911 R 1246995 CDS YP_008733300.1 556564875 17442623 complement(2110460..2111203) 1 NC_022657.1 COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit; succinate dehydrogenase/fumarate reductase iron-sulfur subunit 2111203 17442623 AFR_09790 Actinoplanes friuliensis DSM 7358 succinate dehydrogenase/fumarate reductase iron-sulfur subunit YP_008733300.1 2110460 R 1246995 CDS YP_008733301.1 556564876 17442624 complement(2111203..2113131) 1 NC_022657.1 COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit; succinate dehydrogenase flavoprotein subunit 2113131 sdhA 17442624 sdhA Actinoplanes friuliensis DSM 7358 succinate dehydrogenase flavoprotein subunit YP_008733301.1 2111203 R 1246995 CDS YP_008733302.1 556564877 17442625 complement(2113133..2113765) 1 NC_022657.1 COG0833 Amino acid transporters; putative succinate dehydrogenase cytochrome b-556 subunit 2113765 17442625 AFR_09800 Actinoplanes friuliensis DSM 7358 putative succinate dehydrogenase cytochrome b-556 subunit YP_008733302.1 2113133 R 1246995 CDS YP_008733303.1 556564878 17442626 2114062..2114898 1 NC_022657.1 COG0583 Transcriptional regulator; putative LysR-family transcriptional regulator 2114898 17442626 AFR_09805 Actinoplanes friuliensis DSM 7358 putative LysR-family transcriptional regulator YP_008733303.1 2114062 D 1246995 CDS YP_008733304.1 556564879 17442627 2114909..2116249 1 NC_022657.1 COG1502 Phosphatidylserine/phosphatidylglycerophosphate/cardiolipi n synthases and related enzymes; hypothetical protein 2116249 17442627 AFR_09810 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733304.1 2114909 D 1246995 CDS YP_008733305.1 556564880 17442628 complement(2116236..2116988) 1 NC_022657.1 COG0702 Predicted nucleoside-diphosphate-sugar epimerases; NmrA family protein 2116988 17442628 AFR_09815 Actinoplanes friuliensis DSM 7358 NmrA family protein YP_008733305.1 2116236 R 1246995 CDS YP_008733306.1 556564881 17442629 2117081..2117509 1 NC_022657.1 COG1846 Transcriptional regulators; MarR family transcriptional regulator 2117509 17442629 AFR_09820 Actinoplanes friuliensis DSM 7358 MarR family transcriptional regulator YP_008733306.1 2117081 D 1246995 CDS YP_008733307.1 556564882 17442630 complement(2117514..2118944) 1 NC_022657.1 COG1233 Phytoene dehydrogenase and related proteins; zeta-phytoene desaturase 2118944 17442630 AFR_09825 Actinoplanes friuliensis DSM 7358 zeta-phytoene desaturase YP_008733307.1 2117514 R 1246995 CDS YP_008733308.1 556564883 17442631 complement(2118953..2120047) 1 NC_022657.1 COG0463 Glycosyltransferases involved in cell wall biogenesis; family 2 glycosyl transferase 2120047 17442631 AFR_09830 Actinoplanes friuliensis DSM 7358 family 2 glycosyl transferase YP_008733308.1 2118953 R 1246995 CDS YP_008733309.1 556564884 17442632 complement(2120044..2120811) 1 NC_022657.1 COG2324 Predicted membrane protein; hypothetical protein 2120811 17442632 AFR_09835 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733309.1 2120044 R 1246995 CDS YP_008733310.1 556564885 17442633 complement(2120814..2121395) 1 NC_022657.1 COG0456 Acetyltransferases; N-acetyltransferase GCN5 2121395 17442633 AFR_09840 Actinoplanes friuliensis DSM 7358 N-acetyltransferase GCN5 YP_008733310.1 2120814 R 1246995 CDS YP_008733311.1 556564886 17442634 complement(2121392..2122093) 1 NC_022657.1 spheroidene monooxygenase 2122093 17442634 AFR_09845 Actinoplanes friuliensis DSM 7358 spheroidene monooxygenase YP_008733311.1 2121392 R 1246995 CDS YP_008733312.1 556564887 17442635 complement(2122117..2122605) 1 NC_022657.1 COG2606 Uncharacterized conserved protein; hypothetical protein 2122605 17442635 AFR_09850 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733312.1 2122117 R 1246995 CDS YP_008733313.1 556564888 17442636 complement(2122730..2124079) 1 NC_022657.1 COG4097 Predicted ferric reductase; Respiratory burst oxidase-like protein 2124079 17442636 AFR_09855 Actinoplanes friuliensis DSM 7358 Respiratory burst oxidase-like protein YP_008733313.1 2122730 R 1246995 CDS YP_008733314.1 556564889 17442637 complement(2124166..2125086) 1 NC_022657.1 COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily; putative permease, DMT superfamily protein 2125086 17442637 AFR_09860 Actinoplanes friuliensis DSM 7358 putative permease, DMT superfamily protein YP_008733314.1 2124166 R 1246995 CDS YP_008733315.1 556564890 17442638 complement(2125098..2125907) 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); short-chain dehydrogenase/reductase SDR 2125907 17442638 AFR_09865 Actinoplanes friuliensis DSM 7358 short-chain dehydrogenase/reductase SDR YP_008733315.1 2125098 R 1246995 CDS YP_008733316.1 556564891 17442639 2126619..2127128 1 NC_022657.1 hypothetical protein 2127128 17442639 AFR_09870 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733316.1 2126619 D 1246995 CDS YP_008733317.1 556564892 17442640 complement(2128083..2128322) 1 NC_022657.1 hypothetical protein 2128322 17442640 AFR_09875 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733317.1 2128083 R 1246995 CDS YP_008733318.1 556564893 17442641 2129028..2131001 1 NC_022657.1 COG0389 Nucleotidyltransferase/DNA polymerase involved in DNA repair; hypothetical protein 2131001 17442641 AFR_09880 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733318.1 2129028 D 1246995 CDS YP_008733319.1 556564894 17442642 2131034..2134354 1 NC_022657.1 COG0587 DNA polymerase III, alpha subunit; error-prone DNA polymerase 2134354 dnaE2 17442642 dnaE2 Actinoplanes friuliensis DSM 7358 error-prone DNA polymerase YP_008733319.1 2131034 D 1246995 CDS YP_008733320.1 556564895 17442643 2134446..2134970 1 NC_022657.1 putative subtilisin inhibitor protein 2134970 17442643 AFR_09890 Actinoplanes friuliensis DSM 7358 putative subtilisin inhibitor protein YP_008733320.1 2134446 D 1246995 CDS YP_008733321.1 556564896 17442644 2135076..2138372 1 NC_022657.1 COG1404 Subtilisin-like serine proteases; putative subtilase-family protease 2138372 17442644 AFR_09895 Actinoplanes friuliensis DSM 7358 putative subtilase-family protease YP_008733321.1 2135076 D 1246995 CDS YP_008733322.1 556564897 17442645 2138495..2139199 1 NC_022657.1 COG0500 SAM-dependent methyltransferases; ubiquinone/menaquinone biosynthesis methyltransferase ubiE 2139199 17442645 AFR_09900 Actinoplanes friuliensis DSM 7358 ubiquinone/menaquinone biosynthesis methyltransferase ubiE YP_008733322.1 2138495 D 1246995 CDS YP_008733323.1 556564898 17442646 2139196..2140338 1 NC_022657.1 COG1524 Uncharacterized proteins of the AP superfamily; putative phosphodiesterase/nucleotide pyrophosphatase 2140338 17442646 AFR_09905 Actinoplanes friuliensis DSM 7358 putative phosphodiesterase/nucleotide pyrophosphatase YP_008733323.1 2139196 D 1246995 CDS YP_008733324.1 556564899 17442647 2140459..2141664 1 NC_022657.1 COG0389 Nucleotidyltransferase/DNA polymerase involved in DNA repair; DNA-directed DNA polymerase 2141664 17442647 AFR_09910 Actinoplanes friuliensis DSM 7358 DNA-directed DNA polymerase YP_008733324.1 2140459 D 1246995 CDS YP_008733325.1 556564900 17442648 2141757..2142143 1 NC_022657.1 hypothetical protein 2142143 17442648 AFR_09915 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733325.1 2141757 D 1246995 CDS YP_008733326.1 556564901 17442649 complement(2143121..2145556) 1 NC_022657.1 COG1305 Transglutaminase-like enzymes, putative cysteine proteases; hypothetical protein 2145556 17442649 AFR_09920 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733326.1 2143121 R 1246995 CDS YP_008733327.1 556564902 17442650 complement(2145597..2146865) 1 NC_022657.1 COG1721 Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain); hypothetical protein 2146865 17442650 AFR_09925 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733327.1 2145597 R 1246995 CDS YP_008733328.1 556564903 17442651 complement(2146888..2147937) 1 NC_022657.1 COG0714 MoxR-like ATPases; putative ATPase associated with various cellular activities 2147937 17442651 AFR_09930 Actinoplanes friuliensis DSM 7358 putative ATPase associated with various cellular activities YP_008733328.1 2146888 R 1246995 CDS YP_008733329.1 556564904 17442652 2148347..2151166 1 NC_022657.1 COG0495 Leucyl-tRNA synthetase; leucyl-tRNA ligase 2151166 leuS 17442652 leuS Actinoplanes friuliensis DSM 7358 leucyl-tRNA ligase YP_008733329.1 2148347 D 1246995 CDS YP_008733330.1 556564905 17442653 2151241..2152497 1 NC_022657.1 COG0128 5-enolpyruvylshikimate-3-phosphate synthase; 3-phosphoshikimate 1-carboxyvinyltransferase 2152497 17442653 AFR_09940 Actinoplanes friuliensis DSM 7358 3-phosphoshikimate 1-carboxyvinyltransferase YP_008733330.1 2151241 D 1246995 CDS YP_008733331.1 556564906 17442654 complement(2154053..2154334) 1 NC_022657.1 COG0398 Uncharacterized conserved protein; hypothetical protein 2154334 17442654 AFR_09945 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733331.1 2154053 R 1246995 CDS YP_008733332.1 556564907 17442655 2154453..2154716 1 NC_022657.1 hypothetical protein 2154716 17442655 AFR_09950 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733332.1 2154453 D 1246995 CDS YP_008733333.1 556564908 17442656 complement(2154834..2155550) 1 NC_022657.1 COG3442 Predicted glutamine amidotransferase; cobyric acid synthase 2155550 17442656 AFR_09955 Actinoplanes friuliensis DSM 7358 cobyric acid synthase YP_008733333.1 2154834 R 1246995 CDS YP_008733334.1 556564909 17442657 complement(2155540..2156676) 1 NC_022657.1 COG0769 UDP-N-acetylmuramyl tripeptide synthase; UDP-N-acetylmuramate--L-alanine ligase 2156676 17442657 AFR_09960 Actinoplanes friuliensis DSM 7358 UDP-N-acetylmuramate--L-alanine ligase YP_008733334.1 2155540 R 1246995 CDS YP_008733335.1 556564910 17442658 2157425..2158198 1 NC_022657.1 COG0791 Cell wall-associated hydrolases (invasion-associated proteins); hypothetical protein 2158198 17442658 AFR_09965 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733335.1 2157425 D 1246995 CDS YP_008733336.1 556564911 17442659 2158608..2159039 1 NC_022657.1 COG2001 Uncharacterized protein conserved in bacteria; cell division protein MraZ 2159039 17442659 AFR_09970 Actinoplanes friuliensis DSM 7358 cell division protein MraZ YP_008733336.1 2158608 D 1246995 CDS YP_008733337.1 556564912 17442660 2159258..2160223 1 NC_022657.1 COG0275 Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis; 16S rRNA m(4)C1402 methyltransferase 2160223 17442660 AFR_09975 Actinoplanes friuliensis DSM 7358 16S rRNA m(4)C1402 methyltransferase YP_008733337.1 2159258 D 1246995 CDS YP_008733338.1 556564913 17442661 2160323..2160913 1 NC_022657.1 hypothetical protein 2160913 17442661 AFR_09980 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733338.1 2160323 D 1246995 CDS YP_008733339.1 556564914 17442662 2160916..2163315 1 NC_022657.1 COG0768 Cell division protein FtsI/penicillin-binding protein 2; putative penicillin-binding protein 2163315 17442662 AFR_09985 Actinoplanes friuliensis DSM 7358 putative penicillin-binding protein YP_008733339.1 2160916 D 1246995 CDS YP_008733340.1 556564915 17442663 2163370..2164884 1 NC_022657.1 COG0769 UDP-N-acetylmuramyl tripeptide synthase; UDP-N-acetylmuramyl tripeptide synthetase 2164884 17442663 AFR_09990 Actinoplanes friuliensis DSM 7358 UDP-N-acetylmuramyl tripeptide synthetase YP_008733340.1 2163370 D 1246995 CDS YP_008733341.1 556564916 17442664 2164890..2166278 1 NC_022657.1 COG0770 UDP-N-acetylmuramyl pentapeptide synthase; UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate- -D-alanyl-D-alanine ligase 2166278 17442664 AFR_09995 Actinoplanes friuliensis DSM 7358 UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate- -D-alanyl-D-alanine ligase YP_008733341.1 2164890 D 1246995 CDS YP_008733342.1 556564917 17442665 2166275..2167378 1 NC_022657.1 COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase; phospho-N-acetylmuramoyl-pentapeptide- transferase 2167378 mraY 17442665 mraY Actinoplanes friuliensis DSM 7358 phospho-N-acetylmuramoyl-pentapeptide- transferase YP_008733342.1 2166275 D 1246995 CDS YP_008733343.1 556564918 17442666 2167443..2168897 1 NC_022657.1 COG0772 Bacterial cell division membrane protein; cell division protein FtsW 2168897 17442666 AFR_10005 Actinoplanes friuliensis DSM 7358 cell division protein FtsW YP_008733343.1 2167443 D 1246995 CDS YP_008733344.1 556564919 17442667 2168897..2170006 1 NC_022657.1 COG0707 UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase; UDP-N-acetylglucosamine-N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase 2170006 17442667 AFR_10010 Actinoplanes friuliensis DSM 7358 UDP-N-acetylglucosamine-N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase YP_008733344.1 2168897 D 1246995 CDS YP_008733345.1 556564920 17442668 2170038..2171456 1 NC_022657.1 COG0773 UDP-N-acetylmuramate-alanine ligase; putative UDP-N-acetylmuramoyl-L-alanine ligase 2171456 17442668 AFR_10015 Actinoplanes friuliensis DSM 7358 putative UDP-N-acetylmuramoyl-L-alanine ligase YP_008733345.1 2170038 D 1246995 CDS YP_008733346.1 556564921 17442669 2171509..2172246 1 NC_022657.1 COG1589 Cell division septal protein; putative cell division protein FtsQ 2172246 17442669 AFR_10020 Actinoplanes friuliensis DSM 7358 putative cell division protein FtsQ YP_008733346.1 2171509 D 1246995 CDS YP_008733347.1 556564922 17442670 2172529..2173665 1 NC_022657.1 COG0206 Cell division GTPase; putative cell division protein FtsZ 2173665 17442670 AFR_10025 Actinoplanes friuliensis DSM 7358 putative cell division protein FtsZ YP_008733347.1 2172529 D 1246995 CDS YP_008733348.1 556564923 17442671 2173670..2174383 1 NC_022657.1 COG0325 Predicted enzyme with a TIM-barrel fold; hypothetical protein 2174383 17442671 AFR_10030 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733348.1 2173670 D 1246995 CDS YP_008733349.1 556564924 17442672 2174607..2175299 1 NC_022657.1 COG1799 Uncharacterized protein conserved in bacteria; hypothetical protein 2175299 17442672 AFR_10035 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733349.1 2174607 D 1246995 CDS YP_008733350.1 556564925 17442673 2175323..2175628 1 NC_022657.1 COG0762 Predicted integral membrane protein; YggT family protein 2175628 17442673 AFR_10040 Actinoplanes friuliensis DSM 7358 YggT family protein YP_008733350.1 2175323 D 1246995 CDS YP_008733351.1 556564926 17442674 2175687..2176508 1 NC_022657.1 COG3599 Cell division initiation protein; putative DivIVA family protein 2176508 17442674 AFR_10045 Actinoplanes friuliensis DSM 7358 putative DivIVA family protein YP_008733351.1 2175687 D 1246995 CDS YP_008733352.1 556564927 17442675 2176552..2177439 1 NC_022657.1 hypothetical protein 2177439 17442675 AFR_10050 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733352.1 2176552 D 1246995 CDS YP_008733353.1 556564928 17442676 2178060..2178398 1 NC_022657.1 COG1872 Uncharacterized conserved protein; hypothetical protein 2178398 17442676 AFR_10055 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733353.1 2178060 D 1246995 CDS YP_008733354.1 556564929 17442677 2178395..2179906 1 NC_022657.1 COG3263 NhaP-type Na+/H+ and K+/H+ antiporters with a unique C-terminal domain; potassium/proton antiporter 2179906 17442677 AFR_10060 Actinoplanes friuliensis DSM 7358 potassium/proton antiporter YP_008733354.1 2178395 D 1246995 CDS YP_008733355.1 556564930 17442678 2180200..2180622 1 NC_022657.1 COG1734 DnaK suppressor protein; putative TraR/DksA-family transcriptional regulator 2180622 17442678 AFR_10065 Actinoplanes friuliensis DSM 7358 putative TraR/DksA-family transcriptional regulator YP_008733355.1 2180200 D 1246995 CDS YP_008733356.1 556564931 17442679 2180700..2181209 1 NC_022657.1 COG0597 Lipoprotein signal peptidase; putative signal peptidase II 2181209 17442679 AFR_10070 Actinoplanes friuliensis DSM 7358 putative signal peptidase II YP_008733356.1 2180700 D 1246995 CDS YP_008733357.1 556564932 17442680 2181206..2182132 1 NC_022657.1 COG0564 Pseudouridylate synthases, 23S RNA-specific; ribosomal large subunit pseudouridine synthase D 2182132 17442680 AFR_10075 Actinoplanes friuliensis DSM 7358 ribosomal large subunit pseudouridine synthase D YP_008733357.1 2181206 D 1246995 CDS YP_008733358.1 556564933 17442681 2182178..2183191 1 NC_022657.1 hypothetical protein 2183191 17442681 AFR_10080 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733358.1 2182178 D 1246995 CDS YP_008733359.1 556564934 17442682 2183374..2185035 1 NC_022657.1 COG0455 ATPases involved in chromosome partitioning; hypothetical protein 2185035 17442682 AFR_10085 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733359.1 2183374 D 1246995 CDS YP_008733360.1 556564935 17442683 2185120..2188656 1 NC_022657.1 COG0587 DNA polymerase III, alpha subunit; DNA polymerase III subunit alpha 2188656 dnaE 17442683 dnaE Actinoplanes friuliensis DSM 7358 DNA polymerase III subunit alpha YP_008733360.1 2185120 D 1246995 CDS YP_008733361.1 556564936 17442684 2188700..2189434 1 NC_022657.1 hypothetical protein 2189434 17442684 AFR_10095 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733361.1 2188700 D 1246995 CDS YP_008733362.1 556564937 17442685 complement(2189349..2190059) 1 NC_022657.1 COG2802 Uncharacterized protein, similar to the N-terminal domain of Lon protease; hypothetical protein 2190059 17442685 AFR_10100 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733362.1 2189349 R 1246995 CDS YP_008733363.1 556564938 17442686 2190208..2191518 1 NC_022657.1 COG0141 Histidinol dehydrogenase; bifunctional histidinal dehydrogenase/ histidinol dehydrogenase 2191518 hisD 17442686 hisD Actinoplanes friuliensis DSM 7358 bifunctional histidinal dehydrogenase/ histidinol dehydrogenase YP_008733363.1 2190208 D 1246995 CDS YP_008733364.1 556564939 17442687 2191515..2192579 1 NC_022657.1 COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; histidinol-phosphate aminotransferase 2192579 17442687 AFR_10110 Actinoplanes friuliensis DSM 7358 histidinol-phosphate aminotransferase YP_008733364.1 2191515 D 1246995 CDS YP_008733365.1 556564940 17442688 2192576..2193187 1 NC_022657.1 COG0131 Imidazoleglycerol-phosphate dehydratase; imidazoleglycerol-phosphate dehydratase 2193187 hisB 17442688 hisB Actinoplanes friuliensis DSM 7358 imidazoleglycerol-phosphate dehydratase YP_008733365.1 2192576 D 1246995 CDS YP_008733366.1 556564941 17442689 2193184..2193351 1 NC_022657.1 hypothetical protein 2193351 17442689 AFR_10120 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733366.1 2193184 D 1246995 CDS YP_008733367.1 556564942 17442690 2193351..2193974 1 NC_022657.1 COG0118 Glutamine amidotransferase; imidazole glycerol phosphate synthase subunit HisH 2193974 hisH 17442690 hisH Actinoplanes friuliensis DSM 7358 imidazole glycerol phosphate synthase subunit HisH YP_008733367.1 2193351 D 1246995 CDS YP_008733368.1 556564943 17442691 2193971..2194291 1 NC_022657.1 hypothetical protein 2194291 17442691 AFR_10130 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733368.1 2193971 D 1246995 CDS YP_008733369.1 556564944 17442692 2194322..2195047 1 NC_022657.1 COG0106 Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase; phosphoribosyl isomerase A 2195047 17442692 AFR_10135 Actinoplanes friuliensis DSM 7358 phosphoribosyl isomerase A YP_008733369.1 2194322 D 1246995 CDS YP_008733370.1 556564945 17442693 2195044..2195454 1 NC_022657.1 COG0251 Putative translation initiation inhibitor, yjgF family; endoribonuclease L-PSP 2195454 17442693 AFR_10140 Actinoplanes friuliensis DSM 7358 endoribonuclease L-PSP YP_008733370.1 2195044 D 1246995 CDS YP_008733371.1 556564946 17442694 complement(2195478..2196371) 1 NC_022657.1 COG0583 Transcriptional regulator; putative LysR-family transcriptional regulator 2196371 17442694 AFR_10145 Actinoplanes friuliensis DSM 7358 putative LysR-family transcriptional regulator YP_008733371.1 2195478 R 1246995 CDS YP_008733372.1 556564947 17442695 2196444..2197688 1 NC_022657.1 COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily; hypothetical protein 2197688 17442695 AFR_10150 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733372.1 2196444 D 1246995 CDS YP_008733373.1 556564948 17442696 2197945..2198721 1 NC_022657.1 COG0107 Imidazoleglycerol-phosphate synthase; imidazole glycerol phosphate synthase subunit HisF 2198721 17442696 AFR_10155 Actinoplanes friuliensis DSM 7358 imidazole glycerol phosphate synthase subunit HisF YP_008733373.1 2197945 D 1246995 CDS YP_008733374.1 556564949 17442697 complement(2199168..2199596) 1 NC_022657.1 hypothetical protein 2199596 17442697 AFR_10160 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733374.1 2199168 R 1246995 CDS YP_008733375.1 556564950 17442698 complement(2199714..2200319) 1 NC_022657.1 COG2364 Predicted membrane protein; hypothetical protein 2200319 17442698 AFR_10165 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733375.1 2199714 R 1246995 CDS YP_008733376.1 556564951 17442699 2200448..2201875 1 NC_022657.1 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs; DeoR family transcriptional regulator 2201875 17442699 AFR_10170 Actinoplanes friuliensis DSM 7358 DeoR family transcriptional regulator YP_008733376.1 2200448 D 1246995 CDS YP_008733377.1 556564952 17442700 2202844..2203539 1 NC_022657.1 COG0726 Predicted xylanase/chitin deacetylase; Chitooligosaccharide deacetylase 2203539 17442700 AFR_10175 Actinoplanes friuliensis DSM 7358 Chitooligosaccharide deacetylase YP_008733377.1 2202844 D 1246995 CDS YP_008733378.1 556564953 17442701 complement(2203536..2204003) 1 NC_022657.1 COG1129 ABC-type sugar transport system, ATPase component; hypothetical protein 2204003 17442701 AFR_10180 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733378.1 2203536 R 1246995 CDS YP_008733379.1 556564954 17442702 complement(2204000..2204341) 1 NC_022657.1 hypothetical protein 2204341 17442702 AFR_10185 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733379.1 2204000 R 1246995 CDS YP_008733380.1 556564955 17442703 2204433..2205287 1 NC_022657.1 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; ECF subfamily RNA polymerase sigma-24 subunit 2205287 17442703 AFR_10190 Actinoplanes friuliensis DSM 7358 ECF subfamily RNA polymerase sigma-24 subunit YP_008733380.1 2204433 D 1246995 CDS YP_008733381.1 556564956 17442704 complement(2205317..2207140) 1 NC_022657.1 COG1022 Long-chain acyl-CoA synthetases (AMP-forming); long-chain acyl-CoA synthetase 2207140 17442704 AFR_10195 Actinoplanes friuliensis DSM 7358 long-chain acyl-CoA synthetase YP_008733381.1 2205317 R 1246995 CDS YP_008733382.1 556564957 17442705 2207461..2208660 1 NC_022657.1 COG1404 Subtilisin-like serine proteases; putative subtilase-family protease 2208660 17442705 AFR_10200 Actinoplanes friuliensis DSM 7358 putative subtilase-family protease YP_008733382.1 2207461 D 1246995 CDS YP_008733383.1 556564958 17442706 complement(2208740..2209144) 1 NC_022657.1 COG3212 Predicted membrane protein; HtpX-like protease 2209144 17442706 AFR_10205 Actinoplanes friuliensis DSM 7358 HtpX-like protease YP_008733383.1 2208740 R 1246995 CDS YP_008733384.1 556564959 17442707 complement(2209234..2209965) 1 NC_022657.1 COG0500 SAM-dependent methyltransferases; methyltransferase 2209965 17442707 AFR_10210 Actinoplanes friuliensis DSM 7358 methyltransferase YP_008733384.1 2209234 R 1246995 CDS YP_008733385.1 556564960 17442708 complement(2209986..2211260) 1 NC_022657.1 COG0642 Signal transduction histidine kinase; Phytochrome 1 2211260 17442708 AFR_10215 Actinoplanes friuliensis DSM 7358 Phytochrome 1 YP_008733385.1 2209986 R 1246995 CDS YP_008733386.1 556564961 17442709 complement(2211257..2211940) 1 NC_022657.1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; putative two-component system response regulator 2211940 17442709 AFR_10220 Actinoplanes friuliensis DSM 7358 putative two-component system response regulator YP_008733386.1 2211257 R 1246995 CDS YP_008733387.1 556564962 17442710 2212063..2212527 1 NC_022657.1 hypothetical protein 2212527 17442710 AFR_10225 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733387.1 2212063 D 1246995 CDS YP_008733388.1 556564963 17442711 2212582..2213985 1 NC_022657.1 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs; GntR family transcriptional regulator 2213985 17442711 AFR_10230 Actinoplanes friuliensis DSM 7358 GntR family transcriptional regulator YP_008733388.1 2212582 D 1246995 CDS YP_008733389.1 556564964 17442712 complement(2213880..2215169) 1 NC_022657.1 COG0531 Amino acid transporters; putative amino-acid permease 2215169 17442712 AFR_10235 Actinoplanes friuliensis DSM 7358 putative amino-acid permease YP_008733389.1 2213880 R 1246995 CDS YP_008733390.1 556564965 17442713 complement(2215237..2215866) 1 NC_022657.1 hypothetical protein 2215866 17442713 AFR_10240 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733390.1 2215237 R 1246995 CDS YP_008733391.1 556564966 17442714 2216058..2217830 1 NC_022657.1 COG1132 ABC-type multidrug transport system, ATPase and permease components; Lipid A export ATP-binding/permease protein msbA 2217830 17442714 AFR_10245 Actinoplanes friuliensis DSM 7358 Lipid A export ATP-binding/permease protein msbA YP_008733391.1 2216058 D 1246995 CDS YP_008733392.1 556564967 17442715 2217827..2219608 1 NC_022657.1 COG1132 ABC-type multidrug transport system, ATPase and permease components; putative ABC transporter ATPase and permease protein 2219608 17442715 AFR_10250 Actinoplanes friuliensis DSM 7358 putative ABC transporter ATPase and permease protein YP_008733392.1 2217827 D 1246995 CDS YP_008733393.1 556564968 17442716 complement(2219619..2220227) 1 NC_022657.1 COG0522 Ribosomal protein S4 and related proteins; 30S ribosomal protein S4 2220227 rpsD 17442716 rpsD Actinoplanes friuliensis DSM 7358 30S ribosomal protein S4 YP_008733393.1 2219619 R 1246995 CDS YP_008733394.1 556564969 17442717 2220314..2221054 1 NC_022657.1 COG0587 DNA polymerase III, alpha subunit; hypothetical protein 2221054 17442717 AFR_10260 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733394.1 2220314 D 1246995 CDS YP_008733395.1 556564970 17442718 complement(2221061..2221663) 1 NC_022657.1 COG1309 Transcriptional regulator; regulatory protein TetR 2221663 17442718 AFR_10265 Actinoplanes friuliensis DSM 7358 regulatory protein TetR YP_008733395.1 2221061 R 1246995 CDS YP_008733396.1 556564971 17442719 complement(2221677..2222414) 1 NC_022657.1 COG0842 ABC-type multidrug transport system, permease component; ABC transporter permease 2222414 17442719 AFR_10270 Actinoplanes friuliensis DSM 7358 ABC transporter permease YP_008733396.1 2221677 R 1246995 CDS YP_008733397.1 556564972 17442720 complement(2222479..2223204) 1 NC_022657.1 COG1131 ABC-type multidrug transport system, ATPase component; ABC transporter-like protein 2223204 17442720 AFR_10275 Actinoplanes friuliensis DSM 7358 ABC transporter-like protein YP_008733397.1 2222479 R 1246995 CDS YP_008733398.1 556564973 17442721 complement(2223329..2225167) 1 NC_022657.1 hypothetical protein 2225167 17442721 AFR_10280 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733398.1 2223329 R 1246995 CDS YP_008733399.1 556564974 17442722 2225395..2225769 1 NC_022657.1 COG0139 Phosphoribosyl-AMP cyclohydrolase; phosphoribosyl-AMP cyclohydrolase 2225769 17442722 AFR_10285 Actinoplanes friuliensis DSM 7358 phosphoribosyl-AMP cyclohydrolase YP_008733399.1 2225395 D 1246995 CDS YP_008733400.1 556564975 17442723 2225766..2227310 1 NC_022657.1 COG0147 Anthranilate/para-aminobenzoate synthases component I; anthranilate synthase component I 2227310 17442723 AFR_10290 Actinoplanes friuliensis DSM 7358 anthranilate synthase component I YP_008733400.1 2225766 D 1246995 CDS YP_008733401.1 556564976 17442724 2227328..2227849 1 NC_022657.1 hypothetical protein 2227849 17442724 AFR_10295 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733401.1 2227328 D 1246995 CDS YP_008733402.1 556564977 17442725 complement(2227783..2227983) 1 NC_022657.1 hypothetical protein 2227983 17442725 AFR_10300 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733402.1 2227783 R 1246995 CDS YP_008733403.1 556564978 17442726 2228469..2229272 1 NC_022657.1 COG0134 Indole-3-glycerol phosphate synthase; putative indole-3-glycerol phosphate synthase 2229272 17442726 AFR_10305 Actinoplanes friuliensis DSM 7358 putative indole-3-glycerol phosphate synthase YP_008733403.1 2228469 D 1246995 CDS YP_008733404.1 556564979 17442727 2229269..2230510 1 NC_022657.1 COG0133 Tryptophan synthase beta chain; tryptophan synthase subunit beta 2230510 17442727 AFR_10310 Actinoplanes friuliensis DSM 7358 tryptophan synthase subunit beta YP_008733404.1 2229269 D 1246995 CDS YP_008733405.1 556564980 17442728 2230507..2231310 1 NC_022657.1 COG0159 Tryptophan synthase alpha chain; tryptophan synthase subunit alpha 2231310 trpA 17442728 trpA Actinoplanes friuliensis DSM 7358 tryptophan synthase subunit alpha YP_008733405.1 2230507 D 1246995 CDS YP_008733406.1 556564981 17442729 2231348..2232430 1 NC_022657.1 COG0682 Prolipoprotein diacylglyceryltransferase; putative prolipoprotein diacylglyceryl transferase 2232430 17442729 AFR_10320 Actinoplanes friuliensis DSM 7358 putative prolipoprotein diacylglyceryl transferase YP_008733406.1 2231348 D 1246995 CDS YP_008733407.1 556564982 17442730 2232459..2233661 1 NC_022657.1 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases; tRNA uridine 5-carboxymethylaminomethyl modification protein MnmG 2233661 17442730 AFR_10325 Actinoplanes friuliensis DSM 7358 tRNA uridine 5-carboxymethylaminomethyl modification protein MnmG YP_008733407.1 2232459 D 1246995 CDS YP_008733408.1 556564983 17442731 complement(2233667..2234536) 1 NC_022657.1 COG3393 Predicted acetyltransferase; putative GCN5-related N-acetyltransferase 2234536 17442731 AFR_10330 Actinoplanes friuliensis DSM 7358 putative GCN5-related N-acetyltransferase YP_008733408.1 2233667 R 1246995 CDS YP_008733409.1 556564984 17442732 2234809..2239299 1 NC_022657.1 COG0067 Glutamate synthase domain 1; putative glutamate synthase large subunit 2239299 17442732 AFR_10335 Actinoplanes friuliensis DSM 7358 putative glutamate synthase large subunit YP_008733409.1 2234809 D 1246995 CDS YP_008733410.1 556564985 17442733 2239292..2240767 1 NC_022657.1 COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases; glutamate synthase (NADPH/NADH) small chain 2240767 17442733 AFR_10340 Actinoplanes friuliensis DSM 7358 glutamate synthase (NADPH/NADH) small chain YP_008733410.1 2239292 D 1246995 CDS YP_008733411.1 556564986 17442734 2240822..2241391 1 NC_022657.1 hypothetical protein 2241391 17442734 AFR_10345 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733411.1 2240822 D 1246995 CDS YP_008733412.1 556564987 17442735 2241606..2241956 1 NC_022657.1 hypothetical protein 2241956 17442735 AFR_10350 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733412.1 2241606 D 1246995 CDS YP_008733413.1 556564988 17442736 complement(2241953..2243728) 1 NC_022657.1 von Willebrand factor type A 2243728 17442736 AFR_10355 Actinoplanes friuliensis DSM 7358 von Willebrand factor type A YP_008733413.1 2241953 R 1246995 CDS YP_008733414.1 556564989 17442737 complement(2243728..2244711) 1 NC_022657.1 COG4249 Uncharacterized protein containing caspase domain; hypothetical protein 2244711 17442737 AFR_10360 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733414.1 2243728 R 1246995 CDS YP_008733415.1 556564990 17442738 2245084..2246532 1 NC_022657.1 COG0469 Pyruvate kinase; pyruvate kinase 2246532 17442738 AFR_10365 Actinoplanes friuliensis DSM 7358 pyruvate kinase YP_008733415.1 2245084 D 1246995 CDS YP_008733416.1 556564991 17442739 2246544..2247410 1 NC_022657.1 COG1946 Acyl-CoA thioesterase; acyl-CoA thioesterase II 2247410 17442739 AFR_10370 Actinoplanes friuliensis DSM 7358 acyl-CoA thioesterase II YP_008733416.1 2246544 D 1246995 CDS YP_008733417.1 556564992 17442740 complement(2247919..2249169) 1 NC_022657.1 hypothetical protein 2249169 17442740 AFR_10375 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733417.1 2247919 R 1246995 CDS YP_008733418.1 556564993 17442741 complement(2249300..2249998) 1 NC_022657.1 hypothetical protein 2249998 17442741 AFR_10380 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733418.1 2249300 R 1246995 CDS YP_008733419.1 556564994 17442743 2250323..2250904 1 NC_022657.1 COG3707 Response regulator with putative antiterminator output domain; response regulator NasT 2250904 17442743 AFR_10385 Actinoplanes friuliensis DSM 7358 response regulator NasT YP_008733419.1 2250323 D 1246995 CDS YP_008733420.1 556564995 17442744 2251290..2252285 1 NC_022657.1 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component; Leu/Ile/Val-binding protein 2252285 17442744 AFR_10390 Actinoplanes friuliensis DSM 7358 Leu/Ile/Val-binding protein YP_008733420.1 2251290 D 1246995 CDS YP_008733421.1 556564996 17442745 2252366..2253316 1 NC_022657.1 COG0559 Branched-chain amino acid ABC-type transport system, permease components; MglC-like galactoside transport system permease protein 2253316 17442745 AFR_10395 Actinoplanes friuliensis DSM 7358 MglC-like galactoside transport system permease protein YP_008733421.1 2252366 D 1246995 CDS YP_008733422.1 556564997 17442746 2253334..2254443 1 NC_022657.1 COG4177 ABC-type branched-chain amino acid transport system, permease component; High-affinity branched-chain amino acid transport system permease protein livM 2254443 17442746 AFR_10400 Actinoplanes friuliensis DSM 7358 High-affinity branched-chain amino acid transport system permease protein livM YP_008733422.1 2253334 D 1246995 CDS YP_008733423.1 556564998 17442747 2254436..2255335 1 NC_022657.1 COG0411 ABC-type branched-chain amino acid transport systems, ATPase component; spermidine/putrescine import ATP-binding protein potA 2255335 17442747 AFR_10405 Actinoplanes friuliensis DSM 7358 spermidine/putrescine import ATP-binding protein potA YP_008733423.1 2254436 D 1246995 CDS YP_008733424.1 556564999 17442748 2255325..2256035 1 NC_022657.1 COG0410 ABC-type branched-chain amino acid transport systems, ATPase component; phosphate import ATP-binding protein pstB 2256035 17442748 AFR_10410 Actinoplanes friuliensis DSM 7358 phosphate import ATP-binding protein pstB YP_008733424.1 2255325 D 1246995 CDS YP_008733425.1 556565000 17442749 2256068..2256979 1 NC_022657.1 COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; Membrane-bound lytic murein transglycosylase F 2256979 17442749 AFR_10415 Actinoplanes friuliensis DSM 7358 Membrane-bound lytic murein transglycosylase F YP_008733425.1 2256068 D 1246995 CDS YP_008733426.1 556565001 17442750 2256987..2257988 1 NC_022657.1 COG0765 ABC-type amino acid transport system, permease component; Octopine transport system permease protein occM 2257988 17442750 AFR_10420 Actinoplanes friuliensis DSM 7358 Octopine transport system permease protein occM YP_008733426.1 2256987 D 1246995 CDS YP_008733427.1 556565002 17442751 2258009..2258761 1 NC_022657.1 COG1126 ABC-type polar amino acid transport system, ATPase component; ABC transporter ATP-binding protein 2258761 17442751 AFR_10425 Actinoplanes friuliensis DSM 7358 ABC transporter ATP-binding protein YP_008733427.1 2258009 D 1246995 CDS YP_008733428.1 556565003 17442752 2258816..2261509 1 NC_022657.1 COG0258 5'-3' exonuclease (including N-terminal domain of PolI); putative DNA polymerase I 2261509 17442752 AFR_10430 Actinoplanes friuliensis DSM 7358 putative DNA polymerase I YP_008733428.1 2258816 D 1246995 CDS YP_008733429.1 556565004 17442753 2262643..2262984 1 NC_022657.1 COG0640 Predicted transcriptional regulators; ArsR family transcriptional regulator 2262984 17442753 AFR_10435 Actinoplanes friuliensis DSM 7358 ArsR family transcriptional regulator YP_008733429.1 2262643 D 1246995 CDS YP_008733430.1 556565005 17442754 complement(2263801..2264121) 1 NC_022657.1 hypothetical protein 2264121 17442754 AFR_10440 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733430.1 2263801 R 1246995 CDS YP_008733431.1 556565006 17442755 complement(2264111..2264329) 1 NC_022657.1 hypothetical protein 2264329 17442755 AFR_10445 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733431.1 2264111 R 1246995 CDS YP_008733432.1 556565007 17442756 complement(2264347..2265165) 1 NC_022657.1 COG0500 SAM-dependent methyltransferases; methyltransferase 2265165 17442756 AFR_10450 Actinoplanes friuliensis DSM 7358 methyltransferase YP_008733432.1 2264347 R 1246995 CDS YP_008733433.1 556565008 17442757 2265499..2267019 1 NC_022657.1 COG0539 Ribosomal protein S1; 30S ribosomal protein S1 2267019 rpsA 17442757 rpsA Actinoplanes friuliensis DSM 7358 30S ribosomal protein S1 YP_008733433.1 2265499 D 1246995 CDS YP_008733434.1 556565009 17442758 2267112..2268287 1 NC_022657.1 COG0237 Dephospho-CoA kinase; dephospho-CoA kinase/protein folding accessory domain-containing protein 2268287 coaE 17442758 coaE Actinoplanes friuliensis DSM 7358 dephospho-CoA kinase/protein folding accessory domain-containing protein YP_008733434.1 2267112 D 1246995 CDS YP_008733435.1 556565010 17442759 2268651..2270768 1 NC_022657.1 COG0556 Helicase subunit of the DNA excision repair complex; excinuclease ABC subunit B 2270768 17442759 AFR_10465 Actinoplanes friuliensis DSM 7358 excinuclease ABC subunit B YP_008733435.1 2268651 D 1246995 CDS YP_008733436.1 556565011 17442760 2270773..2271162 1 NC_022657.1 COG5485 Predicted ester cyclase; hypothetical protein 2271162 17442760 AFR_10470 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733436.1 2270773 D 1246995 CDS YP_008733437.1 556565012 17442761 2271933..2272853 1 NC_022657.1 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; GCN5-like N-acetyltransferase 2272853 17442761 AFR_10475 Actinoplanes friuliensis DSM 7358 GCN5-like N-acetyltransferase YP_008733437.1 2271933 D 1246995 CDS YP_008733438.1 556565013 17442762 complement(2272882..2273211) 1 NC_022657.1 COG2329 Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides; antibiotic biosynthesis monooxygenase 2273211 17442762 AFR_10480 Actinoplanes friuliensis DSM 7358 antibiotic biosynthesis monooxygenase YP_008733438.1 2272882 R 1246995 CDS YP_008733439.1 556565014 17442763 2273534..2274529 1 NC_022657.1 COG0861 Membrane protein TerC, possibly involved in tellurium resistance; hypothetical protein 2274529 17442763 AFR_10485 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733439.1 2273534 D 1246995 CDS YP_008733440.1 556565015 17442764 complement(2274583..2276451) 1 NC_022657.1 COG1217 Predicted membrane GTPase involved in stress response; putative GTP-binding elongation factor 2276451 17442764 AFR_10490 Actinoplanes friuliensis DSM 7358 putative GTP-binding elongation factor YP_008733440.1 2274583 R 1246995 CDS YP_008733441.1 556565016 17442765 2276614..2277414 1 NC_022657.1 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains); putative lytic transglycosylase 2277414 17442765 AFR_10495 Actinoplanes friuliensis DSM 7358 putative lytic transglycosylase YP_008733441.1 2276614 D 1246995 CDS YP_008733442.1 556565017 17442766 2277599..2278021 1 NC_022657.1 COG0080 Ribosomal protein L11; 50S ribosomal protein L11 2278021 rplK 17442766 rplK Actinoplanes friuliensis DSM 7358 50S ribosomal protein L11 YP_008733442.1 2277599 D 1246995 CDS YP_008733443.1 556565018 17442767 complement(2278068..2278673) 1 NC_022657.1 COG0740 Protease subunit of ATP-dependent Clp proteases; ATP-dependent Clp protease proteolytic subunit 2278673 17442767 AFR_10505 Actinoplanes friuliensis DSM 7358 ATP-dependent Clp protease proteolytic subunit YP_008733443.1 2278068 R 1246995 CDS YP_008733444.1 556565019 17442768 2278794..2279408 1 NC_022657.1 COG1335 Amidases related to nicotinamidase; isochorismatase hydrolase 2279408 17442768 AFR_10510 Actinoplanes friuliensis DSM 7358 isochorismatase hydrolase YP_008733444.1 2278794 D 1246995 CDS YP_008733445.1 556565020 17442769 complement(2279413..2280066) 1 NC_022657.1 COG0491 Zn-dependent hydrolases, including glyoxylases; beta-lactamase domain-containing protein 2280066 17442769 AFR_10515 Actinoplanes friuliensis DSM 7358 beta-lactamase domain-containing protein YP_008733445.1 2279413 R 1246995 CDS YP_008733446.1 556565021 17442770 complement(2280068..2280766) 1 NC_022657.1 mycothiol-dependent maleylpyruvate isomerase 2280766 17442770 AFR_10520 Actinoplanes friuliensis DSM 7358 mycothiol-dependent maleylpyruvate isomerase YP_008733446.1 2280068 R 1246995 CDS YP_008733447.1 556565022 17442771 2280950..2281990 1 NC_022657.1 COG1162 Predicted GTPases; ribosome biogenesis GTPase 2281990 17442771 AFR_10525 Actinoplanes friuliensis DSM 7358 ribosome biogenesis GTPase YP_008733447.1 2280950 D 1246995 CDS YP_008733448.1 556565023 17442772 2282015..2283811 1 NC_022657.1 hypothetical protein 2283811 17442772 AFR_10530 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733448.1 2282015 D 1246995 CDS YP_008733449.1 556565024 17442773 2283922..2286879 1 NC_022657.1 COG0178 Excinuclease ATPase subunit; excinuclease ABC subunit A 2286879 uvrA 17442773 uvrA Actinoplanes friuliensis DSM 7358 excinuclease ABC subunit A YP_008733449.1 2283922 D 1246995 CDS YP_008733450.1 556565025 17442774 2287172..2287630 1 NC_022657.1 COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases; Cytochrome b6-f complex iron-sulfur subunit 2287630 17442774 AFR_10540 Actinoplanes friuliensis DSM 7358 Cytochrome b6-f complex iron-sulfur subunit YP_008733450.1 2287172 D 1246995 CDS YP_008733451.1 556565026 17442775 2287767..2290310 1 NC_022657.1 COG0322 Nuclease subunit of the excinuclease complex; UvrABC system protein C 2290310 17442775 AFR_10545 Actinoplanes friuliensis DSM 7358 UvrABC system protein C YP_008733451.1 2287767 D 1246995 CDS YP_008733452.1 556565027 17442776 2290518..2291441 1 NC_022657.1 COG1660 Predicted P-loop-containing kinase; glmZ(sRNA)-inactivating NTPase 2291441 17442776 AFR_10550 Actinoplanes friuliensis DSM 7358 glmZ(sRNA)-inactivating NTPase YP_008733452.1 2290518 D 1246995 CDS YP_008733453.1 556565028 17442777 2291438..2292898 1 NC_022657.1 COG0391 Uncharacterized conserved protein; hypothetical protein 2292898 17442777 AFR_10555 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733453.1 2291438 D 1246995 CDS YP_008733454.1 556565029 17442778 2292940..2293920 1 NC_022657.1 COG1481 Uncharacterized protein conserved in bacteria; putative sporulation transcription regulator whiA 2293920 17442778 AFR_10560 Actinoplanes friuliensis DSM 7358 putative sporulation transcription regulator whiA YP_008733454.1 2292940 D 1246995 CDS YP_008733455.1 556565030 17442779 2294354..2295349 1 NC_022657.1 COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; glyceraldehyde-3-phosphate dehydrogenase 2295349 17442779 AFR_10565 Actinoplanes friuliensis DSM 7358 glyceraldehyde-3-phosphate dehydrogenase YP_008733455.1 2294354 D 1246995 CDS YP_008733456.1 556565031 17442780 2295355..2296551 1 NC_022657.1 COG0126 3-phosphoglycerate kinase; phosphoglycerate kinase 2296551 pgk 17442780 pgk Actinoplanes friuliensis DSM 7358 phosphoglycerate kinase YP_008733456.1 2295355 D 1246995 CDS YP_008733457.1 556565032 17442781 2296554..2297345 1 NC_022657.1 COG0149 Triosephosphate isomerase; triosephosphate isomerase 2297345 tpiA 17442781 tpiA Actinoplanes friuliensis DSM 7358 triosephosphate isomerase YP_008733457.1 2296554 D 1246995 CDS YP_008733458.1 556565033 17442782 2297436..2297690 1 NC_022657.1 COG1314 Preprotein translocase subunit SecG; preprotein translocase subunit SecG 2297690 17442782 AFR_10580 Actinoplanes friuliensis DSM 7358 preprotein translocase subunit SecG YP_008733458.1 2297436 D 1246995 CDS YP_008733459.1 556565034 17442783 2297868..2298215 1 NC_022657.1 electron transport protein 2298215 17442783 AFR_10585 Actinoplanes friuliensis DSM 7358 electron transport protein YP_008733459.1 2297868 D 1246995 CDS YP_008733460.1 556565035 17442784 complement(2298304..2298912) 1 NC_022657.1 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; N-acetyltransferase GCN5 2298912 17442784 AFR_10590 Actinoplanes friuliensis DSM 7358 N-acetyltransferase GCN5 YP_008733460.1 2298304 R 1246995 CDS YP_008733461.1 556565036 17442785 complement(2299005..2299457) 1 NC_022657.1 hypothetical protein 2299457 17442785 AFR_10595 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733461.1 2299005 R 1246995 CDS YP_008733462.1 556565037 17442786 2299487..2300071 1 NC_022657.1 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; ECF subfamily RNA polymerase sigma-24 factor 2300071 17442786 AFR_10600 Actinoplanes friuliensis DSM 7358 ECF subfamily RNA polymerase sigma-24 factor YP_008733462.1 2299487 D 1246995 CDS YP_008733463.1 556565038 17442787 2300068..2300424 1 NC_022657.1 hypothetical protein 2300424 17442787 AFR_10605 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733463.1 2300068 D 1246995 CDS YP_008733464.1 556565039 17442788 2300524..2300793 1 NC_022657.1 COG1987 Flagellar biosynthesis pathway, component FliQ; Flagellar biosynthetic protein fliQ 2300793 17442788 AFR_10610 Actinoplanes friuliensis DSM 7358 Flagellar biosynthetic protein fliQ YP_008733464.1 2300524 D 1246995 CDS YP_008733465.1 556565040 17442789 complement(2300848..2301597) 1 NC_022657.1 COG0363 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase; putative 6-phosphogluconolactonase 2301597 17442789 AFR_10615 Actinoplanes friuliensis DSM 7358 putative 6-phosphogluconolactonase YP_008733465.1 2300848 R 1246995 CDS YP_008733466.1 556565041 17442790 complement(2301680..2302708) 1 NC_022657.1 COG3429 Glucose-6-P dehydrogenase subunit; Putative OxPP cycle protein opcA 2302708 17442790 AFR_10620 Actinoplanes friuliensis DSM 7358 Putative OxPP cycle protein opcA YP_008733466.1 2301680 R 1246995 CDS YP_008733467.1 556565042 17442791 complement(2302693..2304144) 1 NC_022657.1 COG0364 Glucose-6-phosphate 1-dehydrogenase; glucose-6-phosphate 1-dehydrogenase 2304144 17442791 AFR_10625 Actinoplanes friuliensis DSM 7358 glucose-6-phosphate 1-dehydrogenase YP_008733467.1 2302693 R 1246995 CDS YP_008733468.1 556565043 17442792 complement(2304261..2305706) 1 NC_022657.1 phosphoglucose isomerase 2305706 17442792 AFR_10630 Actinoplanes friuliensis DSM 7358 phosphoglucose isomerase YP_008733468.1 2304261 R 1246995 CDS YP_008733469.1 556565044 17442793 complement(2305706..2306845) 1 NC_022657.1 COG0176 Transaldolase; transaldolase 2306845 17442793 AFR_10635 Actinoplanes friuliensis DSM 7358 transaldolase YP_008733469.1 2305706 R 1246995 CDS YP_008733470.1 556565045 17442794 complement(2306855..2308963) 1 NC_022657.1 COG0021 Transketolase; transketolase 2308963 17442794 AFR_10640 Actinoplanes friuliensis DSM 7358 transketolase YP_008733470.1 2306855 R 1246995 CDS YP_008733471.1 556565046 17442795 2309242..2310207 1 NC_022657.1 COG0109 Polyprenyltransferase (cytochrome oxidase assembly factor); protoheme IX farnesyltransferase 2310207 17442795 AFR_10645 Actinoplanes friuliensis DSM 7358 protoheme IX farnesyltransferase YP_008733471.1 2309242 D 1246995 CDS YP_008733472.1 556565047 17442796 2310415..2310711 1 NC_022657.1 hypothetical protein 2310711 17442796 AFR_10650 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733472.1 2310415 D 1246995 CDS YP_008733473.1 556565048 17442797 complement(2311959..2312912) 1 NC_022657.1 COG1612 Uncharacterized protein required for cytochrome oxidase assembly; putative cytochrome oxidase assembly protein 2312912 17442797 AFR_10655 Actinoplanes friuliensis DSM 7358 putative cytochrome oxidase assembly protein YP_008733473.1 2311959 R 1246995 CDS YP_008733474.1 556565049 17442798 2313020..2313784 1 NC_022657.1 COG2345 Predicted transcriptional regulator; putative ArsR-family transcriptional regulator 2313784 17442798 AFR_10660 Actinoplanes friuliensis DSM 7358 putative ArsR-family transcriptional regulator YP_008733474.1 2313020 D 1246995 CDS YP_008733475.1 556565050 17442799 2313781..2315214 1 NC_022657.1 COG0719 ABC-type transport system involved in Fe-S cluster assembly, permease component; putative FeS assembly protein SufB 2315214 17442799 AFR_10665 Actinoplanes friuliensis DSM 7358 putative FeS assembly protein SufB YP_008733475.1 2313781 D 1246995 CDS YP_008733476.1 556565051 17442800 2315277..2316395 1 NC_022657.1 COG0719 ABC-type transport system involved in Fe-S cluster assembly, permease component; putative FeS assembly protein SufD 2316395 17442800 AFR_10670 Actinoplanes friuliensis DSM 7358 putative FeS assembly protein SufD YP_008733476.1 2315277 D 1246995 CDS YP_008733477.1 556565052 17442801 2316392..2316724 1 NC_022657.1 COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases; hypothetical protein 2316724 17442801 AFR_10675 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733477.1 2316392 D 1246995 CDS YP_008733478.1 556565053 17442802 2316721..2317485 1 NC_022657.1 COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component; putative FeS assembly ATPase SufC 2317485 17442802 AFR_10680 Actinoplanes friuliensis DSM 7358 putative FeS assembly ATPase SufC YP_008733478.1 2316721 D 1246995 CDS YP_008733479.1 556565054 17442803 2317503..2318732 1 NC_022657.1 COG0520 Selenocysteine lyase; cysteine desulfurase / selenocysteine lyase 2318732 17442803 AFR_10685 Actinoplanes friuliensis DSM 7358 cysteine desulfurase / selenocysteine lyase YP_008733479.1 2317503 D 1246995 CDS YP_008733480.1 556565055 17442804 2318732..2319187 1 NC_022657.1 COG0822 NifU homolog involved in Fe-S cluster formation; suf system fes assembly protein, nifu family 2319187 17442804 AFR_10690 Actinoplanes friuliensis DSM 7358 suf system fes assembly protein, nifu family YP_008733480.1 2318732 D 1246995 CDS YP_008733481.1 556565056 17442805 2319273..2319752 1 NC_022657.1 COG2151 Predicted metal-sulfur cluster biosynthetic enzyme; hypothetical protein 2319752 17442805 AFR_10695 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733481.1 2319273 D 1246995 CDS YP_008733482.1 556565057 17442806 complement(2319815..2320552) 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); 3-oxoacyl-ACP reductase 2320552 17442806 AFR_10700 Actinoplanes friuliensis DSM 7358 3-oxoacyl-ACP reductase YP_008733482.1 2319815 R 1246995 CDS YP_008733483.1 556565058 17442807 complement(2320557..2321564) 1 NC_022657.1 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases; dehydrogenase 2321564 17442807 AFR_10705 Actinoplanes friuliensis DSM 7358 dehydrogenase YP_008733483.1 2320557 R 1246995 CDS YP_008733484.1 556565059 17442808 complement(2321564..2322406) 1 NC_022657.1 COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway); fumarylacetoacetate (FAA) hydrolase 2322406 17442808 AFR_10710 Actinoplanes friuliensis DSM 7358 fumarylacetoacetate (FAA) hydrolase YP_008733484.1 2321564 R 1246995 CDS YP_008733485.1 556565060 17442809 complement(2322403..2323326) 1 NC_022657.1 COG3386 Gluconolactonase; hypothetical protein 2323326 17442809 AFR_10715 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733485.1 2322403 R 1246995 CDS YP_008733486.1 556565061 17442810 complement(2323323..2324039) 1 NC_022657.1 COG1414 Transcriptional regulator; IclR family transcriptional regulator 2324039 17442810 AFR_10720 Actinoplanes friuliensis DSM 7358 IclR family transcriptional regulator YP_008733486.1 2323323 R 1246995 CDS YP_008733487.1 556565062 17442811 2324141..2325859 1 NC_022657.1 COG0129 Dihydroxyacid dehydratase/phosphogluconate dehydratase; dihydroxy-acid dehydratase IlvD 2325859 17442811 AFR_10725 Actinoplanes friuliensis DSM 7358 dihydroxy-acid dehydratase IlvD YP_008733487.1 2324141 D 1246995 CDS YP_008733488.1 556565063 17442812 2325900..2326646 1 NC_022657.1 hypothetical protein 2326646 17442812 AFR_10730 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733488.1 2325900 D 1246995 CDS YP_008733489.1 556565064 17442813 complement(2326647..2327342) 1 NC_022657.1 COG0406 Fructose-2,6-bisphosphatase; phosphoglycerate mutase 2327342 17442813 AFR_10735 Actinoplanes friuliensis DSM 7358 phosphoglycerate mutase YP_008733489.1 2326647 R 1246995 CDS YP_008733490.1 556565065 17442814 2327509..2328105 1 NC_022657.1 lysine exporter protein 2328105 17442814 AFR_10740 Actinoplanes friuliensis DSM 7358 lysine exporter protein YP_008733490.1 2327509 D 1246995 CDS YP_008733491.1 556565066 17442815 complement(2328404..2329060) 1 NC_022657.1 COG4912 Predicted DNA alkylation repair enzyme; putative DNA alkylation repair enzyme 2329060 17442815 AFR_10745 Actinoplanes friuliensis DSM 7358 putative DNA alkylation repair enzyme YP_008733491.1 2328404 R 1246995 CDS YP_008733492.1 556565067 17442816 2329497..2330354 1 NC_022657.1 putative transcriptional regulator 2330354 17442816 AFR_10750 Actinoplanes friuliensis DSM 7358 putative transcriptional regulator YP_008733492.1 2329497 D 1246995 CDS YP_008733493.1 556565068 17442817 2330586..2331449 1 NC_022657.1 XRE family transcriptional regulator 2331449 17442817 AFR_10755 Actinoplanes friuliensis DSM 7358 XRE family transcriptional regulator YP_008733493.1 2330586 D 1246995 CDS YP_008733494.1 556565069 17442818 2331609..2332379 1 NC_022657.1 putative DNA-binding protein 2332379 17442818 AFR_10760 Actinoplanes friuliensis DSM 7358 putative DNA-binding protein YP_008733494.1 2331609 D 1246995 CDS YP_008733495.1 556565070 17442819 complement(2332381..2332842) 1 NC_022657.1 hypothetical protein 2332842 17442819 AFR_10765 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733495.1 2332381 R 1246995 CDS YP_008733496.1 556565071 17442820 2333138..2333800 1 NC_022657.1 hypothetical protein 2333800 17442820 AFR_10770 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733496.1 2333138 D 1246995 CDS YP_008733497.1 556565072 17442821 complement(2334406..2335326) 1 NC_022657.1 COG2321 Predicted metalloprotease; hypothetical protein 2335326 17442821 AFR_10775 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733497.1 2334406 R 1246995 CDS YP_008733498.1 556565073 17442822 2335562..2337166 1 NC_022657.1 COG0488 ATPase components of ABC transporters with duplicated ATPase domains; ybiT-like ABC transporter ATP-binding protein 2337166 17442822 AFR_10780 Actinoplanes friuliensis DSM 7358 ybiT-like ABC transporter ATP-binding protein YP_008733498.1 2335562 D 1246995 CDS YP_008733499.1 556565074 17442823 2337654..2337881 1 NC_022657.1 transcriptional regulator 2337881 17442823 AFR_10785 Actinoplanes friuliensis DSM 7358 transcriptional regulator YP_008733499.1 2337654 D 1246995 CDS YP_008733500.1 556565075 17442824 2338265..2338657 1 NC_022657.1 COG1024 Enoyl-CoA hydratase/carnithine racemase; enoyl-CoA hydratase/isomerase 2338657 17442824 AFR_10790 Actinoplanes friuliensis DSM 7358 enoyl-CoA hydratase/isomerase YP_008733500.1 2338265 D 1246995 CDS YP_008733501.1 556565076 17442825 2338750..2340699 1 NC_022657.1 COG1132 ABC-type multidrug transport system, ATPase and permease components; Lipid A export ATP-binding/permease protein msbA 2340699 17442825 AFR_10795 Actinoplanes friuliensis DSM 7358 Lipid A export ATP-binding/permease protein msbA YP_008733501.1 2338750 D 1246995 CDS YP_008733502.1 556565077 17442826 2340817..2341020 1 NC_022657.1 hypothetical protein 2341020 17442826 AFR_10800 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733502.1 2340817 D 1246995 CDS YP_008733503.1 556565078 17442827 2341070..2341627 1 NC_022657.1 hypothetical protein 2341627 17442827 AFR_10805 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733503.1 2341070 D 1246995 CDS YP_008733504.1 556565079 17442828 2341624..2342193 1 NC_022657.1 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins; hypothetical protein 2342193 17442828 AFR_10810 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733504.1 2341624 D 1246995 CDS YP_008733505.1 556565080 17442829 complement(2342196..2342558) 1 NC_022657.1 COG0017 Aspartyl/asparaginyl-tRNA synthetases; hypothetical protein 2342558 17442829 AFR_10815 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733505.1 2342196 R 1246995 CDS YP_008733506.1 556565081 17442830 2342762..2343589 1 NC_022657.1 COG2273 Beta-glucanase/Beta-glucan synthetase; Beta-agarase AgaB34 2343589 17442830 AFR_10820 Actinoplanes friuliensis DSM 7358 Beta-agarase AgaB34 YP_008733506.1 2342762 D 1246995 CDS YP_008733507.1 556565082 17442831 complement(2343634..2344224) 1 NC_022657.1 COG3832 Uncharacterized conserved protein; activator of Hsp90 ATPase 1 family protein 2344224 17442831 AFR_10825 Actinoplanes friuliensis DSM 7358 activator of Hsp90 ATPase 1 family protein YP_008733507.1 2343634 R 1246995 CDS YP_008733508.1 556565083 17442832 complement(2344221..2344574) 1 NC_022657.1 COG0640 Predicted transcriptional regulators; ArsR family transcriptional regulator 2344574 17442832 AFR_10830 Actinoplanes friuliensis DSM 7358 ArsR family transcriptional regulator YP_008733508.1 2344221 R 1246995 CDS YP_008733509.1 556565084 17442833 complement(2344616..2345116) 1 NC_022657.1 COG2940 Proteins containing SET domain; nuclear protein SET 2345116 17442833 AFR_10835 Actinoplanes friuliensis DSM 7358 nuclear protein SET YP_008733509.1 2344616 R 1246995 CDS YP_008733510.1 556565085 17442834 complement(2345113..2345661) 1 NC_022657.1 COG3663 G:T/U mismatch-specific DNA glycosylase; putative uracil-DNA glycosylase 2345661 17442834 AFR_10840 Actinoplanes friuliensis DSM 7358 putative uracil-DNA glycosylase YP_008733510.1 2345113 R 1246995 CDS YP_008733511.1 556565086 17442835 2345941..2347323 1 NC_022657.1 COG0770 UDP-N-acetylmuramyl pentapeptide synthase; UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate/D-alanyl-D-alanyl ligase 2347323 17442835 AFR_10845 Actinoplanes friuliensis DSM 7358 UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate/D-alanyl-D-alanyl ligase YP_008733511.1 2345941 D 1246995 CDS YP_008733512.1 556565087 17442836 complement(2347269..2348024) 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); short-chain dehydrogenase/reductase SDR 2348024 17442836 AFR_10850 Actinoplanes friuliensis DSM 7358 short-chain dehydrogenase/reductase SDR YP_008733512.1 2347269 R 1246995 CDS YP_008733513.1 556565088 17442837 complement(2348049..2348798) 1 NC_022657.1 COG1396 Predicted transcriptional regulators; Putative HTH-type transcriptional regulatory protein 2348798 17442837 AFR_10855 Actinoplanes friuliensis DSM 7358 Putative HTH-type transcriptional regulatory protein YP_008733513.1 2348049 R 1246995 CDS YP_008733514.1 556565089 17442838 2348894..2349256 1 NC_022657.1 hypothetical protein 2349256 17442838 AFR_10860 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733514.1 2348894 D 1246995 CDS YP_008733515.1 556565090 17442839 complement(2349328..2349801) 1 NC_022657.1 COG1917 Uncharacterized conserved protein, contains double-stranded beta-helix domain; hypothetical protein 2349801 17442839 AFR_10865 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733515.1 2349328 R 1246995 CDS YP_008733516.1 556565091 17442840 2349923..2350555 1 NC_022657.1 COG1853 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family; hypothetical protein 2350555 17442840 AFR_10870 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733516.1 2349923 D 1246995 CDS YP_008733517.1 556565092 17442841 complement(2350821..2351561) 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); putative short-chain dehydrogenase 2351561 17442841 AFR_10875 Actinoplanes friuliensis DSM 7358 putative short-chain dehydrogenase YP_008733517.1 2350821 R 1246995 CDS YP_008733518.1 556565093 17442842 complement(2351916..2352320) 1 NC_022657.1 hypothetical protein 2352320 17442842 AFR_10880 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733518.1 2351916 R 1246995 CDS YP_008733519.1 556565094 17442843 complement(2352542..2353360) 1 NC_022657.1 COG3220 Uncharacterized protein conserved in bacteria; hypothetical protein 2353360 17442843 AFR_10885 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733519.1 2352542 R 1246995 CDS YP_008733520.1 556565095 17442844 complement(2353357..2354274) 1 NC_022657.1 hypothetical protein 2354274 17442844 AFR_10890 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733520.1 2353357 R 1246995 CDS YP_008733521.1 556565096 17442845 complement(2354338..2354916) 1 NC_022657.1 COG1309 Transcriptional regulator; TetR family transcriptional regulator 2354916 17442845 AFR_10895 Actinoplanes friuliensis DSM 7358 TetR family transcriptional regulator YP_008733521.1 2354338 R 1246995 CDS YP_008733522.1 556565097 17442846 2355080..2355727 1 NC_022657.1 COG1011 Predicted hydrolase (HAD superfamily); putative haloacid dehalogenase-like hydrolase 2355727 17442846 AFR_10900 Actinoplanes friuliensis DSM 7358 putative haloacid dehalogenase-like hydrolase YP_008733522.1 2355080 D 1246995 CDS YP_008733523.1 556565098 17442847 2355910..2356794 1 NC_022657.1 COG1718 Serine/threonine protein kinase involved in cell cycle control; hypothetical protein 2356794 17442847 AFR_10905 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733523.1 2355910 D 1246995 CDS YP_008733524.1 556565099 17442848 complement(2356859..2357104) 1 NC_022657.1 hypothetical protein 2357104 17442848 AFR_10910 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733524.1 2356859 R 1246995 CDS YP_008733525.1 556565100 17442849 2357232..2358245 1 NC_022657.1 COG0174 Glutamine synthetase; glutamate--ammonia ligase 2358245 17442849 AFR_10915 Actinoplanes friuliensis DSM 7358 glutamate--ammonia ligase YP_008733525.1 2357232 D 1246995 CDS YP_008733526.1 556565101 17442850 complement(2358271..2358702) 1 NC_022657.1 hypothetical protein 2358702 17442850 AFR_10920 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733526.1 2358271 R 1246995 CDS YP_008733527.1 556565102 17442851 complement(2358747..2359490) 1 NC_022657.1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Transcriptional regulatory protein glnR 2359490 17442851 AFR_10925 Actinoplanes friuliensis DSM 7358 Transcriptional regulatory protein glnR YP_008733527.1 2358747 R 1246995 CDS YP_008733528.1 556565103 17442852 complement(2359610..2362384) 1 NC_022657.1 COG1048 Aconitase A; aconitate hydratase 1 2362384 17442852 AFR_10930 Actinoplanes friuliensis DSM 7358 aconitate hydratase 1 YP_008733528.1 2359610 R 1246995 CDS YP_008733529.1 556565104 17442853 2362573..2362962 1 NC_022657.1 hypothetical protein 2362962 17442853 AFR_10935 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733529.1 2362573 D 1246995 CDS YP_008733530.1 556565105 17442854 2362994..2366266 1 NC_022657.1 COG1523 Type II secretory pathway, pullulanase PulA and related glycosidases; putative glycosyl hydrolase 2366266 17442854 AFR_10940 Actinoplanes friuliensis DSM 7358 putative glycosyl hydrolase YP_008733530.1 2362994 D 1246995 CDS YP_008733531.1 556565106 17442855 2366354..2366806 1 NC_022657.1 hypothetical protein 2366806 17442855 AFR_10945 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733531.1 2366354 D 1246995 CDS YP_008733532.1 556565107 17442856 complement(2366781..2367353) 1 NC_022657.1 COG1309 Transcriptional regulator; TetR family transcriptional regulator 2367353 17442856 AFR_10950 Actinoplanes friuliensis DSM 7358 TetR family transcriptional regulator YP_008733532.1 2366781 R 1246995 CDS YP_008733533.1 556565108 17442857 2367484..2368026 1 NC_022657.1 COG2226 Methylase involved in ubiquinone/menaquinone biosynthesis; ubiquinone/menaquinone biosynthesis methylase 2368026 17442857 AFR_10955 Actinoplanes friuliensis DSM 7358 ubiquinone/menaquinone biosynthesis methylase YP_008733533.1 2367484 D 1246995 CDS YP_008733534.1 556565109 17442858 complement(2368327..2368863) 1 NC_022657.1 COG1309 Transcriptional regulator; TetR family transcriptional regulator 2368863 17442858 AFR_10960 Actinoplanes friuliensis DSM 7358 TetR family transcriptional regulator YP_008733534.1 2368327 R 1246995 CDS YP_008733535.1 556565110 17442859 2368922..2370061 1 NC_022657.1 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases; oxidoreductase 2370061 17442859 AFR_10965 Actinoplanes friuliensis DSM 7358 oxidoreductase YP_008733535.1 2368922 D 1246995 CDS YP_008733536.1 556565111 17442860 complement(2370065..2371531) 1 NC_022657.1 COG0006 Xaa-Pro aminopeptidase; X-Pro aminopeptidase 2371531 17442860 AFR_10970 Actinoplanes friuliensis DSM 7358 X-Pro aminopeptidase YP_008733536.1 2370065 R 1246995 CDS YP_008733537.1 556565112 17442861 complement(2371613..2372290) 1 NC_022657.1 hypothetical protein 2372290 17442861 AFR_10975 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733537.1 2371613 R 1246995 CDS YP_008733538.1 556565113 17442862 2372407..2373345 1 NC_022657.1 COG0524 Sugar kinases, ribokinase family; putative PfkB-family carbohydrate kinase 2373345 17442862 AFR_10980 Actinoplanes friuliensis DSM 7358 putative PfkB-family carbohydrate kinase YP_008733538.1 2372407 D 1246995 CDS YP_008733539.1 556565114 17442863 complement(2373782..2374177) 1 NC_022657.1 COG5496 Predicted thioesterase; hypothetical protein 2374177 17442863 AFR_10985 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733539.1 2373782 R 1246995 CDS YP_008733540.1 556565115 17442864 complement(2374187..2376025) 1 NC_022657.1 COG3428 Predicted membrane protein; hypothetical protein 2376025 17442864 AFR_10990 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733540.1 2374187 R 1246995 CDS YP_008733541.1 556565116 17442865 complement(2376589..2377110) 1 NC_022657.1 COG3402 Uncharacterized conserved protein; hypothetical protein 2377110 17442865 AFR_10995 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733541.1 2376589 R 1246995 CDS YP_008733542.1 556565117 17442866 complement(2377121..2377279) 1 NC_022657.1 hypothetical protein 2377279 17442866 AFR_11000 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733542.1 2377121 R 1246995 CDS YP_008733543.1 556565118 17442867 2377634..2378785 1 NC_022657.1 COG0714 MoxR-like ATPases; putative ATPase associated with various cellular activities 2378785 17442867 AFR_11005 Actinoplanes friuliensis DSM 7358 putative ATPase associated with various cellular activities YP_008733543.1 2377634 D 1246995 CDS YP_008733544.1 556565119 17442868 2378795..2379808 1 NC_022657.1 COG1721 Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain); hypothetical protein 2379808 17442868 AFR_11010 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733544.1 2378795 D 1246995 CDS YP_008733545.1 556565120 17442869 2379805..2380755 1 NC_022657.1 COG2304 Uncharacterized protein containing a von Willebrand factor type A (vWA) domain; hypothetical protein 2380755 17442869 AFR_11015 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733545.1 2379805 D 1246995 CDS YP_008733546.1 556565121 17442870 complement(2381102..2382211) 1 NC_022657.1 hypothetical protein 2382211 17442870 AFR_11020 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733546.1 2381102 R 1246995 CDS YP_008733547.1 556565122 17442871 complement(2382208..2383026) 1 NC_022657.1 COG1073 Hydrolases of the alpha/beta superfamily; hypothetical protein 2383026 17442871 AFR_11025 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733547.1 2382208 R 1246995 CDS YP_008733548.1 556565123 17442872 complement(2383089..2383745) 1 NC_022657.1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; putative two-component system response regulator 2383745 17442872 AFR_11030 Actinoplanes friuliensis DSM 7358 putative two-component system response regulator YP_008733548.1 2383089 R 1246995 CDS YP_008733549.1 556565124 17442873 complement(2383742..2384938) 1 NC_022657.1 COG4585 Signal transduction histidine kinase; putative two-component system sensor kinase 2384938 17442873 AFR_11035 Actinoplanes friuliensis DSM 7358 putative two-component system sensor kinase YP_008733549.1 2383742 R 1246995 CDS YP_008733550.1 556565125 17442874 2385091..2385795 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); 3-oxoacyl-ACP reductase 2385795 17442874 AFR_11040 Actinoplanes friuliensis DSM 7358 3-oxoacyl-ACP reductase YP_008733550.1 2385091 D 1246995 CDS YP_008733551.1 556565126 17442875 2385824..2386591 1 NC_022657.1 COG0623 Enoyl-[acyl-carrier-protein] reductase (NADH); enoyl-(acyl carrier protein) reductase 2386591 17442875 AFR_11045 Actinoplanes friuliensis DSM 7358 enoyl-(acyl carrier protein) reductase YP_008733551.1 2385824 D 1246995 CDS YP_008733552.1 556565127 17442876 2386708..2394009 1 NC_022657.1 hypothetical protein 2394009 17442876 AFR_11050 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733552.1 2386708 D 1246995 CDS YP_008733553.1 556565128 17442877 2394047..2395075 1 NC_022657.1 COG0276 Protoheme ferro-lyase (ferrochelatase); ferrochelatase 2395075 hemH 17442877 hemH Actinoplanes friuliensis DSM 7358 ferrochelatase YP_008733553.1 2394047 D 1246995 CDS YP_008733554.1 556565129 17442878 2395072..2395851 1 NC_022657.1 COG0647 Predicted sugar phosphatases of the HAD superfamily; putative haloacid dehalogenase-like hydrolase 2395851 17442878 AFR_11060 Actinoplanes friuliensis DSM 7358 putative haloacid dehalogenase-like hydrolase YP_008733554.1 2395072 D 1246995 CDS YP_008733555.1 556565130 17442879 2396228..2396938 1 NC_022657.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); alpha/beta hydrolase 2396938 17442879 AFR_11065 Actinoplanes friuliensis DSM 7358 alpha/beta hydrolase YP_008733555.1 2396228 D 1246995 CDS YP_008733556.1 556565131 17442880 2397093..2397587 1 NC_022657.1 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; putative NUDIX hydrolase 2397587 17442880 AFR_11070 Actinoplanes friuliensis DSM 7358 putative NUDIX hydrolase YP_008733556.1 2397093 D 1246995 CDS YP_008733557.1 556565132 17442881 2397674..2398849 1 NC_022657.1 COG0840 Methyl-accepting chemotaxis protein; Putative sensory transducer protein 2398849 17442881 AFR_11075 Actinoplanes friuliensis DSM 7358 Putative sensory transducer protein YP_008733557.1 2397674 D 1246995 CDS YP_008733558.1 556565133 17442882 complement(2398855..2399670) 1 NC_022657.1 COG1396 Predicted transcriptional regulators; helix-turn-helix domain-containing protein 2399670 17442882 AFR_11080 Actinoplanes friuliensis DSM 7358 helix-turn-helix domain-containing protein YP_008733558.1 2398855 R 1246995 CDS YP_008733559.1 556565134 17442883 2399773..2400606 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); short-chain dehydrogenase/reductase SDR 2400606 17442883 AFR_11085 Actinoplanes friuliensis DSM 7358 short-chain dehydrogenase/reductase SDR YP_008733559.1 2399773 D 1246995 CDS YP_008733560.1 556565135 17442884 complement(2400620..2401111) 1 NC_022657.1 COG2816 NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding; NUDIX hydrolase 2401111 17442884 AFR_11090 Actinoplanes friuliensis DSM 7358 NUDIX hydrolase YP_008733560.1 2400620 R 1246995 CDS YP_008733561.1 556565136 17442885 complement(2401104..2401832) 1 NC_022657.1 hypothetical protein 2401832 17442885 AFR_11095 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733561.1 2401104 R 1246995 CDS YP_008733562.1 556565137 17442886 2401994..2402779 1 NC_022657.1 hypothetical protein 2402779 17442886 AFR_11100 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733562.1 2401994 D 1246995 CDS YP_008733563.1 556565138 17442887 complement(2402763..2403713) 1 NC_022657.1 COG0640 Predicted transcriptional regulators; ArsR family transcriptional regulator 2403713 17442887 AFR_11105 Actinoplanes friuliensis DSM 7358 ArsR family transcriptional regulator YP_008733563.1 2402763 R 1246995 CDS YP_008733564.1 556565139 17442888 2403786..2404538 1 NC_022657.1 COG2513 PEP phosphonomutase and related enzymes; hypothetical protein 2404538 17442888 AFR_11110 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733564.1 2403786 D 1246995 CDS YP_008733565.1 556565140 17442889 complement(2404580..2405893) 1 NC_022657.1 COG1680 Beta-lactamase class C and other penicillin binding proteins; putative beta-lactamase 2405893 17442889 AFR_11115 Actinoplanes friuliensis DSM 7358 putative beta-lactamase YP_008733565.1 2404580 R 1246995 CDS YP_008733566.1 556565141 17442890 2406023..2406463 1 NC_022657.1 COG1585 Membrane protein implicated in regulation of membrane protease activity; hypothetical protein 2406463 17442890 AFR_11120 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733566.1 2406023 D 1246995 CDS YP_008733567.1 556565142 17442891 2406493..2407608 1 NC_022657.1 COG0330 Membrane protease subunits, stomatin/prohibitin homologs; hypothetical protein 2407608 17442891 AFR_11125 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733567.1 2406493 D 1246995 CDS YP_008733568.1 556565143 17442892 2407787..2408410 1 NC_022657.1 hypothetical protein 2408410 17442892 AFR_11130 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733568.1 2407787 D 1246995 CDS YP_008733569.1 556565144 17442893 2408433..2409035 1 NC_022657.1 COG0262 Dihydrofolate reductase; hypothetical protein 2409035 17442893 AFR_11135 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733569.1 2408433 D 1246995 CDS YP_008733570.1 556565145 17442894 2409038..2409847 1 NC_022657.1 COG0566 rRNA methylases; tRNA/rRNA methyltransferase SpoU 2409847 17442894 AFR_11140 Actinoplanes friuliensis DSM 7358 tRNA/rRNA methyltransferase SpoU YP_008733570.1 2409038 D 1246995 CDS YP_008733571.1 556565146 17442895 2409831..2410373 1 NC_022657.1 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins; acetyltransferase 2410373 17442895 AFR_11145 Actinoplanes friuliensis DSM 7358 acetyltransferase YP_008733571.1 2409831 D 1246995 CDS YP_008733572.1 556565147 17442896 2410373..2411503 1 NC_022657.1 COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities; aminotransferase 2411503 17442896 AFR_11150 Actinoplanes friuliensis DSM 7358 aminotransferase YP_008733572.1 2410373 D 1246995 CDS YP_008733573.1 556565148 17442897 2413609..2413806 1 NC_022657.1 hypothetical protein 2413806 17442897 AFR_11155 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733573.1 2413609 D 1246995 CDS YP_008733574.1 556565149 17442898 2414178..2415305 1 NC_022657.1 COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases; putative flavohemoprotein 2415305 17442898 AFR_11160 Actinoplanes friuliensis DSM 7358 putative flavohemoprotein YP_008733574.1 2414178 D 1246995 CDS YP_008733575.1 556565150 17442899 2415430..2416311 1 NC_022657.1 endonuclease/exonuclease/phosphatase 2416311 17442899 AFR_11165 Actinoplanes friuliensis DSM 7358 endonuclease/exonuclease/phosphatase YP_008733575.1 2415430 D 1246995 CDS YP_008733576.1 556565151 17442900 complement(2416792..2418147) 1 NC_022657.1 hypothetical protein 2418147 17442900 AFR_11170 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733576.1 2416792 R 1246995 CDS YP_008733577.1 556565152 17442901 2418178..2419530 1 NC_022657.1 COG0771 UDP-N-acetylmuramoylalanine-D-glutamate ligase; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase 2419530 murD 17442901 murD Actinoplanes friuliensis DSM 7358 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase YP_008733577.1 2418178 D 1246995 CDS YP_008733578.1 556565153 17442902 2419893..2420864 1 NC_022657.1 COG1737 Transcriptional regulators; putative RpiR-family transcriptional regulator 2420864 17442902 AFR_11180 Actinoplanes friuliensis DSM 7358 putative RpiR-family transcriptional regulator YP_008733578.1 2419893 D 1246995 CDS YP_008733579.1 556565154 17442903 2420915..2422222 1 NC_022657.1 COG1653 ABC-type sugar transport system, periplasmic component; putative ABC transporter substrate-binding protein 2422222 17442903 AFR_11185 Actinoplanes friuliensis DSM 7358 putative ABC transporter substrate-binding protein YP_008733579.1 2420915 D 1246995 CDS YP_008733580.1 556565155 17442904 2422300..2423283 1 NC_022657.1 COG1175 ABC-type sugar transport systems, permease components; ABC transporter permease 2423283 17442904 AFR_11190 Actinoplanes friuliensis DSM 7358 ABC transporter permease YP_008733580.1 2422300 D 1246995 CDS YP_008733581.1 556565156 17442905 2423283..2424182 1 NC_022657.1 COG0395 ABC-type sugar transport system, permease component; putative ABC transporter permease 2424182 17442905 AFR_11195 Actinoplanes friuliensis DSM 7358 putative ABC transporter permease YP_008733581.1 2423283 D 1246995 CDS YP_008733582.1 556565157 17442906 2424218..2425651 1 NC_022657.1 COG1653 ABC-type sugar transport system, periplasmic component; yurO-like ABC transporter extracellular-binding protein 2425651 17442906 AFR_11200 Actinoplanes friuliensis DSM 7358 yurO-like ABC transporter extracellular-binding protein YP_008733582.1 2424218 D 1246995 CDS YP_008733583.1 556565158 17442907 2425706..2426617 1 NC_022657.1 COG1175 ABC-type sugar transport systems, permease components; putative ABC transporter permease protein yurN 2426617 17442907 AFR_11205 Actinoplanes friuliensis DSM 7358 putative ABC transporter permease protein yurN YP_008733583.1 2425706 D 1246995 CDS YP_008733584.1 556565159 17442908 2426649..2427572 1 NC_022657.1 COG0395 ABC-type sugar transport system, permease component; ABC transporter permease 2427572 17442908 AFR_11210 Actinoplanes friuliensis DSM 7358 ABC transporter permease YP_008733584.1 2426649 D 1246995 CDS YP_008733585.1 556565160 17442909 complement(2427629..2428078) 1 NC_022657.1 COG4276 Uncharacterized conserved protein; cyclase/dehydrase 2428078 17442909 AFR_11215 Actinoplanes friuliensis DSM 7358 cyclase/dehydrase YP_008733585.1 2427629 R 1246995 CDS YP_008733586.1 556565161 17442910 complement(2428083..2429288) 1 NC_022657.1 COG0477 Permeases of the major facilitator superfamily; putative MFS transporter 2429288 17442910 AFR_11220 Actinoplanes friuliensis DSM 7358 putative MFS transporter YP_008733586.1 2428083 R 1246995 CDS YP_008733587.1 556565162 17442911 complement(2429285..2431525) 1 NC_022657.1 COG1472 Beta-glucosidase-related glycosidases; glycoside hydrolase family 3 2431525 17442911 AFR_11225 Actinoplanes friuliensis DSM 7358 glycoside hydrolase family 3 YP_008733587.1 2429285 R 1246995 CDS YP_008733588.1 556565163 17442912 2431586..2432182 1 NC_022657.1 COG1309 Transcriptional regulator; transcriptional regulator 2432182 17442912 AFR_11230 Actinoplanes friuliensis DSM 7358 transcriptional regulator YP_008733588.1 2431586 D 1246995 CDS YP_008733589.1 556565164 17442913 2432224..2433903 1 NC_022657.1 COG0749 DNA polymerase I - 3'-5' exonuclease and polymerase domains; bifunctional 3'-5' exonuclease/DNA polymerase 2433903 17442913 AFR_11235 Actinoplanes friuliensis DSM 7358 bifunctional 3'-5' exonuclease/DNA polymerase YP_008733589.1 2432224 D 1246995 CDS YP_008733590.1 556565165 17442914 complement(2433907..2435772) 1 NC_022657.1 COG1222 ATP-dependent 26S proteasome regulatory subunit; hypothetical protein 2435772 17442914 AFR_11240 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733590.1 2433907 R 1246995 CDS YP_008733591.1 556565166 17442915 2436244..2437440 1 NC_022657.1 COG1960 Acyl-CoA dehydrogenases; acyl-CoA dehydrogenase, short-chain specific 2437440 17442915 AFR_11245 Actinoplanes friuliensis DSM 7358 acyl-CoA dehydrogenase, short-chain specific YP_008733591.1 2436244 D 1246995 CDS YP_008733592.1 556565167 17442916 complement(2437433..2437966) 1 NC_022657.1 COG2203 FOG: GAF domain; hypothetical protein 2437966 17442916 AFR_11250 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733592.1 2437433 R 1246995 CDS YP_008733593.1 556565168 17442917 complement(2437963..2438559) 1 NC_022657.1 COG2229 Predicted GTPase; ATP/GTP-binding protein 2438559 17442917 AFR_11255 Actinoplanes friuliensis DSM 7358 ATP/GTP-binding protein YP_008733593.1 2437963 R 1246995 CDS YP_008733594.1 556565169 17442918 complement(2438537..2438914) 1 NC_022657.1 hypothetical protein 2438914 17442918 AFR_11260 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733594.1 2438537 R 1246995 CDS YP_008733595.1 556565170 17442919 complement(2438911..2439336) 1 NC_022657.1 Roadblock/LC7 family protein 2439336 17442919 AFR_11265 Actinoplanes friuliensis DSM 7358 Roadblock/LC7 family protein YP_008733595.1 2438911 R 1246995 CDS YP_008733596.1 556565171 17442920 complement(2439352..2440839) 1 NC_022657.1 COG0642 Signal transduction histidine kinase; ATP-binding region ATPase domain-containing protein 2440839 17442920 AFR_11270 Actinoplanes friuliensis DSM 7358 ATP-binding region ATPase domain-containing protein YP_008733596.1 2439352 R 1246995 CDS YP_008733597.1 556565172 17442921 complement(2440952..2442169) 1 NC_022657.1 COG0498 Threonine synthase; threonine synthase 2442169 17442921 AFR_11275 Actinoplanes friuliensis DSM 7358 threonine synthase YP_008733597.1 2440952 R 1246995 CDS YP_008733598.1 556565173 17442922 complement(2442182..2443702) 1 NC_022657.1 hypothetical protein 2443702 17442922 AFR_11280 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733598.1 2442182 R 1246995 CDS YP_008733599.1 556565174 17442923 2444261..2444647 1 NC_022657.1 hypothetical protein 2444647 17442923 AFR_11285 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733599.1 2444261 D 1246995 CDS YP_008733600.1 556565175 17442924 complement(2444644..2445465) 1 NC_022657.1 COG1988 Predicted membrane-bound metal-dependent hydrolases; hypothetical protein 2445465 17442924 AFR_11290 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733600.1 2444644 R 1246995 CDS YP_008733601.1 556565176 17442925 complement(2445585..2446082) 1 NC_022657.1 hypothetical protein 2446082 17442925 AFR_11295 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733601.1 2445585 R 1246995 CDS YP_008733602.1 556565177 17442926 2446493..2447878 1 NC_022657.1 COG4585 Signal transduction histidine kinase; histidine kinase 2447878 17442926 AFR_11300 Actinoplanes friuliensis DSM 7358 histidine kinase YP_008733602.1 2446493 D 1246995 CDS YP_008733603.1 556565178 17442927 2447875..2448561 1 NC_022657.1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; Transcriptional regulatory protein ydfI 2448561 17442927 AFR_11305 Actinoplanes friuliensis DSM 7358 Transcriptional regulatory protein ydfI YP_008733603.1 2447875 D 1246995 CDS YP_008733604.1 556565179 17442928 complement(2448573..2449322) 1 NC_022657.1 COG0583 Transcriptional regulator; LysR family transcriptional regulator 2449322 17442928 AFR_11310 Actinoplanes friuliensis DSM 7358 LysR family transcriptional regulator YP_008733604.1 2448573 R 1246995 CDS YP_008733605.1 556565180 17442929 2449609..2450163 1 NC_022657.1 COG2085 Predicted dinucleotide-binding enzymes; coenzyme F420-dependent NADP oxidoreductase 2450163 17442929 AFR_11315 Actinoplanes friuliensis DSM 7358 coenzyme F420-dependent NADP oxidoreductase YP_008733605.1 2449609 D 1246995 CDS YP_008733606.1 556565181 17442930 2450385..2451167 1 NC_022657.1 COG1357 Uncharacterized low-complexity proteins; hypothetical protein 2451167 17442930 AFR_11320 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733606.1 2450385 D 1246995 CDS YP_008733607.1 556565182 17442931 2451202..2452323 1 NC_022657.1 hypothetical protein 2452323 17442931 AFR_11325 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733607.1 2451202 D 1246995 CDS YP_008733608.1 556565183 17442932 complement(2452425..2452901) 1 NC_022657.1 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; putative NUDIX hydrolase 2452901 17442932 AFR_11330 Actinoplanes friuliensis DSM 7358 putative NUDIX hydrolase YP_008733608.1 2452425 R 1246995 CDS YP_008733609.1 556565184 17442933 2453000..2453413 1 NC_022657.1 COG1846 Transcriptional regulators; putative MarR-family transcriptional regulator 2453413 17442933 AFR_11335 Actinoplanes friuliensis DSM 7358 putative MarR-family transcriptional regulator YP_008733609.1 2453000 D 1246995 CDS YP_008733610.1 556565185 17442934 complement(2453571..2454359) 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); short chain dehydrogenase 2454359 17442934 AFR_11340 Actinoplanes friuliensis DSM 7358 short chain dehydrogenase YP_008733610.1 2453571 R 1246995 CDS YP_008733611.1 556565186 17442935 complement(2454385..2454729) 1 NC_022657.1 hypothetical protein 2454729 17442935 AFR_11345 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733611.1 2454385 R 1246995 CDS YP_008733612.1 556565187 17442936 2454808..2455602 1 NC_022657.1 COG0789 Predicted transcriptional regulators; MerR family transcriptional regulator 2455602 17442936 AFR_11350 Actinoplanes friuliensis DSM 7358 MerR family transcriptional regulator YP_008733612.1 2454808 D 1246995 CDS YP_008733613.1 556565188 17442937 complement(2455620..2456399) 1 NC_022657.1 COG0730 Predicted permeases; hypothetical protein 2456399 17442937 AFR_11355 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733613.1 2455620 R 1246995 CDS YP_008733614.1 556565189 17442938 2456488..2459103 1 NC_022657.1 COG4883 Uncharacterized protein conserved in archaea; hypothetical protein 2459103 17442938 AFR_11360 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733614.1 2456488 D 1246995 CDS YP_008733615.1 556565190 17442939 2459115..2459948 1 NC_022657.1 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases; luciferase family protein 2459948 17442939 AFR_11365 Actinoplanes friuliensis DSM 7358 luciferase family protein YP_008733615.1 2459115 D 1246995 CDS YP_008733616.1 556565191 17442940 2460019..2463297 1 NC_022657.1 hypothetical protein 2463297 17442940 AFR_11370 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733616.1 2460019 D 1246995 CDS YP_008733617.1 556565192 17442941 complement(2463332..2464111) 1 NC_022657.1 COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family; myo-inositol-1(or 4)-monophosphatase 2464111 17442941 AFR_11375 Actinoplanes friuliensis DSM 7358 myo-inositol-1(or 4)-monophosphatase YP_008733617.1 2463332 R 1246995 CDS YP_008733618.1 556565193 17442942 complement(2464250..2464519) 1 NC_022657.1 hypothetical protein 2464519 17442942 AFR_11380 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733618.1 2464250 R 1246995 CDS YP_008733619.1 556565194 17442943 complement(2465263..2466705) 1 NC_022657.1 hypothetical protein 2466705 17442943 AFR_11385 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733619.1 2465263 R 1246995 CDS YP_008733620.1 556565195 17442944 complement(2467241..2467819) 1 NC_022657.1 hypothetical protein 2467819 17442944 AFR_11390 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733620.1 2467241 R 1246995 CDS YP_008733621.1 556565196 17442945 2467991..2469277 1 NC_022657.1 COG1653 ABC-type sugar transport system, periplasmic component; family 1 extracellular solute-binding protein 2469277 17442945 AFR_11395 Actinoplanes friuliensis DSM 7358 family 1 extracellular solute-binding protein YP_008733621.1 2467991 D 1246995 CDS YP_008733622.1 556565197 17442946 2469274..2470269 1 NC_022657.1 COG1175 ABC-type sugar transport systems, permease components; binding-protein-dependent transport system inner membrane protein 2470269 17442946 AFR_11400 Actinoplanes friuliensis DSM 7358 binding-protein-dependent transport system inner membrane protein YP_008733622.1 2469274 D 1246995 CDS YP_008733623.1 556565198 17442947 2470271..2471110 1 NC_022657.1 COG0395 ABC-type sugar transport system, permease component; binding-protein-dependent transport system inner membrane protein 2471110 17442947 AFR_11405 Actinoplanes friuliensis DSM 7358 binding-protein-dependent transport system inner membrane protein YP_008733623.1 2470271 D 1246995 CDS YP_008733624.1 556565199 17442948 2471121..2472329 1 NC_022657.1 COG3839 ABC-type sugar transport systems, ATPase components; ABC transporter-like protein 2472329 17442948 AFR_11410 Actinoplanes friuliensis DSM 7358 ABC transporter-like protein YP_008733624.1 2471121 D 1246995 CDS YP_008733625.1 556565200 17442949 2472386..2472790 1 NC_022657.1 COG3631 Ketosteroid isomerase-related protein; hypothetical protein 2472790 17442949 AFR_11415 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733625.1 2472386 D 1246995 CDS YP_008733626.1 556565201 17442950 complement(2472780..2473301) 1 NC_022657.1 hypothetical protein 2473301 17442950 AFR_11420 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733626.1 2472780 R 1246995 CDS YP_008733627.1 556565202 17442951 complement(2473331..2473792) 1 NC_022657.1 COG2177 Cell division protein; hypothetical protein 2473792 17442951 AFR_11425 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733627.1 2473331 R 1246995 CDS YP_008733628.1 556565203 17442952 2473892..2474314 1 NC_022657.1 hypothetical protein 2474314 17442952 AFR_11430 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733628.1 2473892 D 1246995 CDS YP_008733629.1 556565204 17442953 2474431..2475213 1 NC_022657.1 hypothetical protein 2475213 17442953 AFR_11435 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733629.1 2474431 D 1246995 CDS YP_008733630.1 556565205 17442954 complement(2475217..2476236) 1 NC_022657.1 COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases); aryl-alcohol dehydrogenase 2476236 17442954 AFR_11440 Actinoplanes friuliensis DSM 7358 aryl-alcohol dehydrogenase YP_008733630.1 2475217 R 1246995 CDS YP_008733631.1 556565206 17442955 complement(2476246..2477604) 1 NC_022657.1 COG0642 Signal transduction histidine kinase; histidine kinase 2477604 17442955 AFR_11445 Actinoplanes friuliensis DSM 7358 histidine kinase YP_008733631.1 2476246 R 1246995 CDS YP_008733632.1 556565207 17442956 complement(2477601..2478254) 1 NC_022657.1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; winged helix family two component transcriptional regulator 2478254 17442956 AFR_11450 Actinoplanes friuliensis DSM 7358 winged helix family two component transcriptional regulator YP_008733632.1 2477601 R 1246995 CDS YP_008733633.1 556565208 17442957 2478406..2478969 1 NC_022657.1 hypothetical protein 2478969 17442957 AFR_11455 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733633.1 2478406 D 1246995 CDS YP_008733634.1 556565209 17442958 complement(2479036..2480841) 1 NC_022657.1 COG0147 Anthranilate/para-aminobenzoate synthases component I; phenazine biosynthesis protein PhzE 2480841 17442958 AFR_11460 Actinoplanes friuliensis DSM 7358 phenazine biosynthesis protein PhzE YP_008733634.1 2479036 R 1246995 CDS YP_008733635.1 556565210 17442959 complement(2481000..2481446) 1 NC_022657.1 hypothetical protein 2481446 17442959 AFR_11465 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733635.1 2481000 R 1246995 CDS YP_008733636.1 556565211 17442960 complement(2481646..2481885) 1 NC_022657.1 hypothetical protein 2481885 17442960 AFR_11470 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733636.1 2481646 R 1246995 CDS YP_008733637.1 556565212 17442961 2482083..2482457 1 NC_022657.1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Transcriptional regulatory protein yycF 2482457 17442961 AFR_11475 Actinoplanes friuliensis DSM 7358 Transcriptional regulatory protein yycF YP_008733637.1 2482083 D 1246995 CDS YP_008733638.1 556565213 17442962 2482521..2484458 1 NC_022657.1 COG0642 Signal transduction histidine kinase; multi-sensor signal transduction histidine kinase 2484458 17442962 AFR_11480 Actinoplanes friuliensis DSM 7358 multi-sensor signal transduction histidine kinase YP_008733638.1 2482521 D 1246995 CDS YP_008733639.1 556565214 17442963 2484613..2485416 1 NC_022657.1 COG1680 Beta-lactamase class C and other penicillin binding proteins; beta-lactamase 2485416 17442963 AFR_11485 Actinoplanes friuliensis DSM 7358 beta-lactamase YP_008733639.1 2484613 D 1246995 CDS YP_008733640.1 556565215 17442964 2485442..2486485 1 NC_022657.1 COG1609 Transcriptional regulators; putative LacI-family transcriptional regulator 2486485 17442964 AFR_11490 Actinoplanes friuliensis DSM 7358 putative LacI-family transcriptional regulator YP_008733640.1 2485442 D 1246995 CDS YP_008733641.1 556565216 17442965 2486554..2488239 1 NC_022657.1 COG0366 Glycosidases; alpha-glucosidase 2488239 17442965 AFR_11495 Actinoplanes friuliensis DSM 7358 alpha-glucosidase YP_008733641.1 2486554 D 1246995 CDS YP_008733642.1 556565217 17442966 complement(2488241..2489332) 1 NC_022657.1 hypothetical protein 2489332 17442966 AFR_11500 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733642.1 2488241 R 1246995 CDS YP_008733643.1 556565218 17442967 complement(2489329..2490069) 1 NC_022657.1 COG0500 SAM-dependent methyltransferases; type 11 methyltransferase 2490069 17442967 AFR_11505 Actinoplanes friuliensis DSM 7358 type 11 methyltransferase YP_008733643.1 2489329 R 1246995 CDS YP_008733644.1 556565219 17442968 complement(2490111..2490410) 1 NC_022657.1 hypothetical protein 2490410 17442968 AFR_11510 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733644.1 2490111 R 1246995 CDS YP_008733645.1 556565220 17442969 complement(2490513..2490959) 1 NC_022657.1 COG1733 Predicted transcriptional regulators; helix-turn-helix HxlR-like protein 2490959 17442969 AFR_11515 Actinoplanes friuliensis DSM 7358 helix-turn-helix HxlR-like protein YP_008733645.1 2490513 R 1246995 CDS YP_008733646.1 556565221 17442970 2491068..2491934 1 NC_022657.1 COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases); oxidoreductase 2491934 17442970 AFR_11520 Actinoplanes friuliensis DSM 7358 oxidoreductase YP_008733646.1 2491068 D 1246995 CDS YP_008733647.1 556565222 17442971 2492002..2493081 1 NC_022657.1 COG3214 Uncharacterized protein conserved in bacteria; hypothetical protein 2493081 17442971 AFR_11525 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733647.1 2492002 D 1246995 CDS YP_008733648.1 556565223 17442972 2493238..2493927 1 NC_022657.1 COG2353 Uncharacterized conserved protein; hypothetical protein 2493927 17442972 AFR_11530 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733648.1 2493238 D 1246995 CDS YP_008733649.1 556565224 17442973 complement(2493951..2495222) 1 NC_022657.1 putative permease 2495222 17442973 AFR_11535 Actinoplanes friuliensis DSM 7358 putative permease YP_008733649.1 2493951 R 1246995 CDS YP_008733650.1 556565225 17442974 complement(2495219..2495908) 1 NC_022657.1 COG1136 ABC-type antimicrobial peptide transport system, ATPase component; ABC transporter ATP-binding protein 2495908 17442974 AFR_11540 Actinoplanes friuliensis DSM 7358 ABC transporter ATP-binding protein YP_008733650.1 2495219 R 1246995 CDS YP_008733651.1 556565226 17442975 complement(2495905..2496903) 1 NC_022657.1 COG0845 Membrane-fusion protein; hypothetical protein 2496903 17442975 AFR_11545 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733651.1 2495905 R 1246995 CDS YP_008733652.1 556565227 17442976 complement(2497003..2498217) 1 NC_022657.1 COG0436 Aspartate/tyrosine/aromatic aminotransferase; aminotransferase AlaT 2498217 17442976 AFR_11550 Actinoplanes friuliensis DSM 7358 aminotransferase AlaT YP_008733652.1 2497003 R 1246995 CDS YP_008733653.1 556565228 17442977 complement(2498240..2499262) 1 NC_022657.1 hypothetical protein 2499262 17442977 AFR_11555 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733653.1 2498240 R 1246995 CDS YP_008733654.1 556565229 17442978 2499408..2499872 1 NC_022657.1 hypothetical protein 2499872 17442978 AFR_11560 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733654.1 2499408 D 1246995 CDS YP_008733655.1 556565230 17442979 complement(2499947..2501665) 1 NC_022657.1 COG0642 Signal transduction histidine kinase; putative histidine kinase, classic 2501665 17442979 AFR_11565 Actinoplanes friuliensis DSM 7358 putative histidine kinase, classic YP_008733655.1 2499947 R 1246995 CDS YP_008733656.1 556565231 17442980 2501809..2502183 1 NC_022657.1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; putative response regulator receiver domain protein 2502183 17442980 AFR_11570 Actinoplanes friuliensis DSM 7358 putative response regulator receiver domain protein YP_008733656.1 2501809 D 1246995 CDS YP_008733657.1 556565232 17442981 2502183..2503292 1 NC_022657.1 COG1413 FOG: HEAT repeat; hypothetical protein 2503292 17442981 AFR_11575 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733657.1 2502183 D 1246995 CDS YP_008733658.1 556565233 17442982 2503289..2504749 1 NC_022657.1 COG1215 Glycosyltransferases, probably involved in cell wall biogenesis; putative glycosyltransferase 2504749 17442982 AFR_11580 Actinoplanes friuliensis DSM 7358 putative glycosyltransferase YP_008733658.1 2503289 D 1246995 CDS YP_008733659.1 556565234 17442983 complement(2504714..2505370) 1 NC_022657.1 hypothetical protein 2505370 17442983 AFR_11585 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733659.1 2504714 R 1246995 CDS YP_008733660.1 556565235 17442984 2505648..2507882 1 NC_022657.1 COG3620 Predicted transcriptional regulator with C-terminal CBS domains; SARP family transcriptional regulator 2507882 17442984 AFR_11590 Actinoplanes friuliensis DSM 7358 SARP family transcriptional regulator YP_008733660.1 2505648 D 1246995 CDS YP_008733661.1 556565236 17442985 2507984..2509171 1 NC_022657.1 COG2208 Serine phosphatase RsbU, regulator of sigma subunit; putative magnesium/manganese-dependent protein phosphatase 2509171 17442985 AFR_11595 Actinoplanes friuliensis DSM 7358 putative magnesium/manganese-dependent protein phosphatase YP_008733661.1 2507984 D 1246995 CDS YP_008733662.1 556565237 17442986 complement(2509152..2509832) 1 NC_022657.1 COG0671 Membrane-associated phospholipid phosphatase; phosphoesterase pa-phosphatase-like protein 2509832 17442986 AFR_11600 Actinoplanes friuliensis DSM 7358 phosphoesterase pa-phosphatase-like protein YP_008733662.1 2509152 R 1246995 CDS YP_008733663.1 556565238 17442987 2510331..2510822 1 NC_022657.1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; putative LuxR-family transcriptional regulator 2510822 17442987 AFR_11605 Actinoplanes friuliensis DSM 7358 putative LuxR-family transcriptional regulator YP_008733663.1 2510331 D 1246995 CDS YP_008733664.1 556565239 17442988 2510876..2511430 1 NC_022657.1 COG4767 Glycopeptide antibiotics resistance protein; hypothetical protein 2511430 17442988 AFR_11610 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733664.1 2510876 D 1246995 CDS YP_008733665.1 556565240 17442989 complement(2511331..2512488) 1 NC_022657.1 COG0438 Glycosyltransferase; putative glycosyltransferase 2512488 17442989 AFR_11615 Actinoplanes friuliensis DSM 7358 putative glycosyltransferase YP_008733665.1 2511331 R 1246995 CDS YP_008733666.1 556565241 17442990 2512831..2514837 1 NC_022657.1 COG1086 Predicted nucleoside-diphosphate sugar epimerases; putative polysaccharide biosynthesis protein 2514837 17442990 AFR_11620 Actinoplanes friuliensis DSM 7358 putative polysaccharide biosynthesis protein YP_008733666.1 2512831 D 1246995 CDS YP_008733667.1 556565242 17442991 2514867..2516123 1 NC_022657.1 COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase; putative UDP-glucose/GDP-mannose dehydrogenase 2516123 17442991 AFR_11625 Actinoplanes friuliensis DSM 7358 putative UDP-glucose/GDP-mannose dehydrogenase YP_008733667.1 2514867 D 1246995 CDS YP_008733668.1 556565243 17442992 2516140..2516784 1 NC_022657.1 COG2148 Sugar transferases involved in lipopolysaccharide synthesis; putative undecaprenyl-phosphate glycosyl-1-phosphate transferase 2516784 17442992 AFR_11630 Actinoplanes friuliensis DSM 7358 putative undecaprenyl-phosphate glycosyl-1-phosphate transferase YP_008733668.1 2516140 D 1246995 CDS YP_008733669.1 556565244 17442993 2516774..2517952 1 NC_022657.1 hypothetical protein 2517952 17442993 AFR_11635 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733669.1 2516774 D 1246995 CDS YP_008733670.1 556565245 17442994 complement(2517904..2518314) 1 NC_022657.1 COG3795 Uncharacterized protein conserved in bacteria; hypothetical protein 2518314 17442994 AFR_11640 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733670.1 2517904 R 1246995 CDS YP_008733671.1 556565246 17442995 complement(2518405..2519346) 1 NC_022657.1 COG0451 Nucleoside-diphosphate-sugar epimerases; putative epimerase/dehydratase 2519346 17442995 AFR_11645 Actinoplanes friuliensis DSM 7358 putative epimerase/dehydratase YP_008733671.1 2518405 R 1246995 CDS YP_008733672.1 556565247 17442996 complement(2519379..2519996) 1 NC_022657.1 COG2085 Predicted dinucleotide-binding enzymes; coenzyme F420-dependent NADP oxidoreductase 2519996 17442996 AFR_11650 Actinoplanes friuliensis DSM 7358 coenzyme F420-dependent NADP oxidoreductase YP_008733672.1 2519379 R 1246995 CDS YP_008733673.1 556565248 17442997 complement(2520035..2520769) 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); short-chain dehydrogenase/reductase SDR 2520769 17442997 AFR_11655 Actinoplanes friuliensis DSM 7358 short-chain dehydrogenase/reductase SDR YP_008733673.1 2520035 R 1246995 CDS YP_008733674.1 556565249 17442998 2520897..2521799 1 NC_022657.1 COG0583 Transcriptional regulator; LysR family transcription regulator 2521799 17442998 AFR_11660 Actinoplanes friuliensis DSM 7358 LysR family transcription regulator YP_008733674.1 2520897 D 1246995 CDS YP_008733675.1 556565250 17442999 2521880..2522284 1 NC_022657.1 hypothetical protein 2522284 17442999 AFR_11665 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733675.1 2521880 D 1246995 CDS YP_008733676.1 556565251 17443000 complement(2522328..2523152) 1 NC_022657.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); chloride peroxidase 2523152 17443000 AFR_11670 Actinoplanes friuliensis DSM 7358 chloride peroxidase YP_008733676.1 2522328 R 1246995 CDS YP_008733677.1 556565252 17443001 2523337..2523789 1 NC_022657.1 COG0456 Acetyltransferases; GCN5-like N-acetyltransferase 2523789 17443001 AFR_11675 Actinoplanes friuliensis DSM 7358 GCN5-like N-acetyltransferase YP_008733677.1 2523337 D 1246995 CDS YP_008733678.1 556565253 17443002 complement(2523776..2525017) 1 NC_022657.1 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases; putative hydroxylase 2525017 17443002 AFR_11680 Actinoplanes friuliensis DSM 7358 putative hydroxylase YP_008733678.1 2523776 R 1246995 CDS YP_008733679.1 556565254 17443003 complement(2525027..2526058) 1 NC_022657.1 hypothetical protein 2526058 17443003 AFR_11685 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733679.1 2525027 R 1246995 CDS YP_008733680.1 556565255 17443004 complement(2526084..2527247) 1 NC_022657.1 hypothetical protein 2527247 17443004 AFR_11690 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733680.1 2526084 R 1246995 CDS YP_008733681.1 556565256 17443005 complement(2527244..2528482) 1 NC_022657.1 COG3307 Lipid A core - O-antigen ligase and related enzymes; putative O-antigen polymerase 2528482 17443005 AFR_11695 Actinoplanes friuliensis DSM 7358 putative O-antigen polymerase YP_008733681.1 2527244 R 1246995 CDS YP_008733682.1 556565257 17443006 complement(2528479..2529771) 1 NC_022657.1 NAD(P)H-quinone oxidoreductase chain 4 2529771 17443006 AFR_11700 Actinoplanes friuliensis DSM 7358 NAD(P)H-quinone oxidoreductase chain 4 YP_008733682.1 2528479 R 1246995 CDS YP_008733683.1 556565258 17443007 complement(2529764..2531365) 1 NC_022657.1 COG0489 ATPases involved in chromosome partitioning; hypothetical protein 2531365 17443007 AFR_11705 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733683.1 2529764 R 1246995 CDS YP_008733684.1 556565259 17443008 complement(2531384..2532646) 1 NC_022657.1 COG0438 Glycosyltransferase; group 1 glycosyl transferase 2532646 17443008 AFR_11710 Actinoplanes friuliensis DSM 7358 group 1 glycosyl transferase YP_008733684.1 2531384 R 1246995 CDS YP_008733685.1 556565260 17443009 complement(2532652..2533779) 1 NC_022657.1 COG0399 Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; putative aminotransferase 2533779 17443009 AFR_11715 Actinoplanes friuliensis DSM 7358 putative aminotransferase YP_008733685.1 2532652 R 1246995 CDS YP_008733686.1 556565261 17443010 complement(2533772..2534548) 1 NC_022657.1 COG0726 Predicted xylanase/chitin deacetylase; putative polysaccharide deacetylase 2534548 17443010 AFR_11720 Actinoplanes friuliensis DSM 7358 putative polysaccharide deacetylase YP_008733686.1 2533772 R 1246995 CDS YP_008733687.1 556565262 17443011 2534714..2535724 1 NC_022657.1 COG2348 Uncharacterized protein involved in methicillin resistance; hypothetical protein 2535724 17443011 AFR_11725 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733687.1 2534714 D 1246995 CDS YP_008733688.1 556565263 17443013 complement(2535862..2536509) 1 NC_022657.1 hypothetical protein 2536509 17443013 AFR_11730 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733688.1 2535862 R 1246995 CDS YP_008733689.1 556565264 17443014 complement(2536516..2536905) 1 NC_022657.1 hypothetical protein 2536905 17443014 AFR_11735 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733689.1 2536516 R 1246995 CDS YP_008733690.1 556565265 17443015 complement(2536942..2537340) 1 NC_022657.1 hypothetical protein 2537340 17443015 AFR_11740 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733690.1 2536942 R 1246995 CDS YP_008733691.1 556565266 17443016 complement(2537399..2538001) 1 NC_022657.1 glyoxalase/bleomycin resistance protein/dioxygenase 2538001 17443016 AFR_11745 Actinoplanes friuliensis DSM 7358 glyoxalase/bleomycin resistance protein/dioxygenase YP_008733691.1 2537399 R 1246995 CDS YP_008733692.1 556565267 17443017 complement(2538190..2538576) 1 NC_022657.1 hypothetical protein 2538576 17443017 AFR_11750 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733692.1 2538190 R 1246995 CDS YP_008733693.1 556565268 17443018 complement(2538590..2539126) 1 NC_022657.1 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins; GCN5-related N-acetyltransferase 2539126 17443018 AFR_11755 Actinoplanes friuliensis DSM 7358 GCN5-related N-acetyltransferase YP_008733693.1 2538590 R 1246995 CDS YP_008733694.1 556565269 17443019 complement(2539156..2539713) 1 NC_022657.1 COG0262 Dihydrofolate reductase; riboflavin biosynthesis protein RibD domain-containing protein 2539713 17443019 AFR_11760 Actinoplanes friuliensis DSM 7358 riboflavin biosynthesis protein RibD domain-containing protein YP_008733694.1 2539156 R 1246995 CDS YP_008733695.1 556565270 17443020 2539828..2540418 1 NC_022657.1 hypothetical protein 2540418 17443020 AFR_11765 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733695.1 2539828 D 1246995 CDS YP_008733696.1 556565271 17443021 complement(2540420..2541106) 1 NC_022657.1 COG0671 Membrane-associated phospholipid phosphatase; Phosphatidic acid phosphatase type 2 domain-containing protein 1B 2541106 17443021 AFR_11770 Actinoplanes friuliensis DSM 7358 Phosphatidic acid phosphatase type 2 domain-containing protein 1B YP_008733696.1 2540420 R 1246995 CDS YP_008733697.1 556565272 17443022 2541239..2542681 1 NC_022657.1 hypothetical protein 2542681 17443022 AFR_11775 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733697.1 2541239 D 1246995 CDS YP_008733698.1 556565273 17443023 2542693..2544027 1 NC_022657.1 hypothetical protein 2544027 17443023 AFR_11780 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733698.1 2542693 D 1246995 CDS YP_008733699.1 556565274 17443024 2544072..2544620 1 NC_022657.1 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins; N-acetyltransferase GCN5 2544620 17443024 AFR_11785 Actinoplanes friuliensis DSM 7358 N-acetyltransferase GCN5 YP_008733699.1 2544072 D 1246995 CDS YP_008733700.1 556565275 17443025 2544620..2544922 1 NC_022657.1 hypothetical protein 2544922 17443025 AFR_11790 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733700.1 2544620 D 1246995 CDS YP_008733701.1 556565276 17443026 complement(2544874..2545710) 1 NC_022657.1 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; hypothetical protein 2545710 17443026 AFR_11795 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733701.1 2544874 R 1246995 CDS YP_008733702.1 556565277 17443027 2545774..2546652 1 NC_022657.1 COG1846 Transcriptional regulators; hypothetical protein 2546652 17443027 AFR_11800 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733702.1 2545774 D 1246995 CDS YP_008733703.1 556565278 17443028 complement(2546768..2547253) 1 NC_022657.1 COG1846 Transcriptional regulators; MarR family transcriptional regulator 2547253 17443028 AFR_11805 Actinoplanes friuliensis DSM 7358 MarR family transcriptional regulator YP_008733703.1 2546768 R 1246995 CDS YP_008733704.1 556565279 17443029 2547388..2548392 1 NC_022657.1 COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases; NADPH quinone oxidoreductase 2548392 17443029 AFR_11810 Actinoplanes friuliensis DSM 7358 NADPH quinone oxidoreductase YP_008733704.1 2547388 D 1246995 CDS YP_008733705.1 556565280 17443030 2548442..2548855 1 NC_022657.1 hypothetical protein 2548855 17443030 AFR_11815 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733705.1 2548442 D 1246995 CDS YP_008733706.1 556565281 17443031 complement(2548845..2549357) 1 NC_022657.1 hypothetical protein 2549357 17443031 AFR_11820 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733706.1 2548845 R 1246995 CDS YP_008733707.1 556565282 17443032 2549428..2550060 1 NC_022657.1 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins; GCN5-like N-acetyltransferase 2550060 17443032 AFR_11825 Actinoplanes friuliensis DSM 7358 GCN5-like N-acetyltransferase YP_008733707.1 2549428 D 1246995 CDS YP_008733708.1 556565283 17443033 complement(2550065..2550367) 1 NC_022657.1 hypothetical protein 2550367 17443033 AFR_11830 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733708.1 2550065 R 1246995 CDS YP_008733709.1 556565284 17443034 2550592..2551818 1 NC_022657.1 COG0477 Permeases of the major facilitator superfamily; major facilitator superfamily protein 2551818 17443034 AFR_11835 Actinoplanes friuliensis DSM 7358 major facilitator superfamily protein YP_008733709.1 2550592 D 1246995 CDS YP_008733710.1 556565285 17443035 complement(2551805..2553424) 1 NC_022657.1 COG0514 Superfamily II DNA helicase; RecQ family ATP-dependent DNA helicase 2553424 17443035 AFR_11840 Actinoplanes friuliensis DSM 7358 RecQ family ATP-dependent DNA helicase YP_008733710.1 2551805 R 1246995 CDS YP_008733711.1 556565286 17443036 complement(2553440..2553754) 1 NC_022657.1 COG2076 Membrane transporters of cations and cationic drugs; small multidrug resistance protein 2553754 17443036 AFR_11845 Actinoplanes friuliensis DSM 7358 small multidrug resistance protein YP_008733711.1 2553440 R 1246995 CDS YP_008733712.1 556565287 17443037 complement(2553860..2554840) 1 NC_022657.1 COG2207 AraC-type DNA-binding domain-containing proteins; AraC family transcriptional regulator 2554840 17443037 AFR_11850 Actinoplanes friuliensis DSM 7358 AraC family transcriptional regulator YP_008733712.1 2553860 R 1246995 CDS YP_008733713.1 556565288 17443038 2554998..2557748 1 NC_022657.1 COG3899 Predicted ATPase; transcriptional regulator 2557748 17443038 AFR_11855 Actinoplanes friuliensis DSM 7358 transcriptional regulator YP_008733713.1 2554998 D 1246995 CDS YP_008733714.1 556565289 17443039 2557867..2558646 1 NC_022657.1 COG2220 Predicted Zn-dependent hydrolases of the beta-lactamase fold; hypothetical protein 2558646 17443039 AFR_11860 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733714.1 2557867 D 1246995 CDS YP_008733715.1 556565290 17443040 2558692..2559645 1 NC_022657.1 COG2207 AraC-type DNA-binding domain-containing proteins; AraC family transcriptional regulator 2559645 17443040 AFR_11865 Actinoplanes friuliensis DSM 7358 AraC family transcriptional regulator YP_008733715.1 2558692 D 1246995 CDS YP_008733716.1 556565291 17443041 2559737..2560546 1 NC_022657.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); secreted protein 2560546 17443041 AFR_11870 Actinoplanes friuliensis DSM 7358 secreted protein YP_008733716.1 2559737 D 1246995 CDS YP_008733717.1 556565292 17443042 2560562..2561362 1 NC_022657.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); hypothetical protein 2561362 17443042 AFR_11875 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733717.1 2560562 D 1246995 CDS YP_008733718.1 556565293 17443043 complement(2561484..2561756) 1 NC_022657.1 helix-turn-helix domain-containing protein 2561756 17443043 AFR_11880 Actinoplanes friuliensis DSM 7358 helix-turn-helix domain-containing protein YP_008733718.1 2561484 R 1246995 CDS YP_008733719.1 556565294 17443044 2561823..2562596 1 NC_022657.1 COG0024 Methionine aminopeptidase; methionine aminopeptidase 2562596 17443044 AFR_11885 Actinoplanes friuliensis DSM 7358 methionine aminopeptidase YP_008733719.1 2561823 D 1246995 CDS YP_008733720.1 556565295 17443045 complement(2562634..2563017) 1 NC_022657.1 hypothetical protein 2563017 17443045 AFR_11890 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733720.1 2562634 R 1246995 CDS YP_008733721.1 556565296 17443046 complement(2563188..2564300) 1 NC_022657.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); epoxide hydrolase 2564300 17443046 AFR_11895 Actinoplanes friuliensis DSM 7358 epoxide hydrolase YP_008733721.1 2563188 R 1246995 CDS YP_008733722.1 556565297 17443047 2564430..2564753 1 NC_022657.1 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); hypothetical protein 2564753 17443047 AFR_11900 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733722.1 2564430 D 1246995 CDS YP_008733723.1 556565298 17443048 2564746..2565123 1 NC_022657.1 COG2172 Anti-sigma regulatory factor (Ser/Thr protein kinase); putative anti-sigma regulatory factor 2565123 17443048 AFR_11905 Actinoplanes friuliensis DSM 7358 putative anti-sigma regulatory factor YP_008733723.1 2564746 D 1246995 CDS YP_008733724.1 556565299 17443049 complement(2565130..2567490) 1 NC_022657.1 COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain; putative signaling protein 2567490 17443049 AFR_11910 Actinoplanes friuliensis DSM 7358 putative signaling protein YP_008733724.1 2565130 R 1246995 CDS YP_008733725.1 556565300 17443050 complement(2567577..2568323) 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); short-chain dehydrogenase/reductase SDR 2568323 17443050 AFR_11915 Actinoplanes friuliensis DSM 7358 short-chain dehydrogenase/reductase SDR YP_008733725.1 2567577 R 1246995 CDS YP_008733726.1 556565301 17443051 2568462..2569352 1 NC_022657.1 COG0583 Transcriptional regulator; LysR family transcriptional regulator 2569352 17443051 AFR_11920 Actinoplanes friuliensis DSM 7358 LysR family transcriptional regulator YP_008733726.1 2568462 D 1246995 CDS YP_008733727.1 556565302 17443052 complement(2569623..2570072) 1 NC_022657.1 COG1846 Transcriptional regulators; MarR family transcriptional regulator 2570072 17443052 AFR_11925 Actinoplanes friuliensis DSM 7358 MarR family transcriptional regulator YP_008733727.1 2569623 R 1246995 CDS YP_008733728.1 556565303 17443053 2570142..2570576 1 NC_022657.1 hypothetical protein 2570576 17443053 AFR_11930 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733728.1 2570142 D 1246995 CDS YP_008733729.1 556565304 17443054 2570800..2573475 1 NC_022657.1 COG3899 Predicted ATPase; LuxR family transcriptional regulator 2573475 17443054 AFR_11935 Actinoplanes friuliensis DSM 7358 LuxR family transcriptional regulator YP_008733729.1 2570800 D 1246995 CDS YP_008733730.1 556565305 17443055 complement(2573481..2574239) 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); oxidoreductase 2574239 17443055 AFR_11940 Actinoplanes friuliensis DSM 7358 oxidoreductase YP_008733730.1 2573481 R 1246995 CDS YP_008733731.1 556565306 17443056 complement(2574260..2575204) 1 NC_022657.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); alpha/beta hydrolase fold protein 2575204 17443056 AFR_11945 Actinoplanes friuliensis DSM 7358 alpha/beta hydrolase fold protein YP_008733731.1 2574260 R 1246995 CDS YP_008733732.1 556565307 17443057 complement(2575201..2575992) 1 NC_022657.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); hypothetical protein 2575992 17443057 AFR_11950 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733732.1 2575201 R 1246995 CDS YP_008733733.1 556565308 17443058 complement(2575989..2576789) 1 NC_022657.1 COG3629 DNA-binding transcriptional activator of the SARP family; SARP family transcriptional regulator 2576789 17443058 AFR_11955 Actinoplanes friuliensis DSM 7358 SARP family transcriptional regulator YP_008733733.1 2575989 R 1246995 CDS YP_008733734.1 556565309 17443059 complement(2576905..2577690) 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); short chain dehydrogenase 2577690 17443059 AFR_11960 Actinoplanes friuliensis DSM 7358 short chain dehydrogenase YP_008733734.1 2576905 R 1246995 CDS YP_008733735.1 556565310 17443060 2577755..2578342 1 NC_022657.1 COG1309 Transcriptional regulator; TetR family transcriptional regulator 2578342 17443060 AFR_11965 Actinoplanes friuliensis DSM 7358 TetR family transcriptional regulator YP_008733735.1 2577755 D 1246995 CDS YP_008733736.1 556565311 17443061 complement(2579035..2580006) 1 NC_022657.1 hypothetical protein 2580006 17443061 AFR_11980 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733736.1 2579035 R 1246995 CDS YP_008733737.1 556565312 17443062 2580189..2581025 1 NC_022657.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); hydrolase 2581025 17443062 AFR_11985 Actinoplanes friuliensis DSM 7358 hydrolase YP_008733737.1 2580189 D 1246995 CDS YP_008733738.1 556565313 17443063 2581018..2581641 1 NC_022657.1 COG1309 Transcriptional regulator; TetR family transcriptional regulator 2581641 17443063 AFR_11990 Actinoplanes friuliensis DSM 7358 TetR family transcriptional regulator YP_008733738.1 2581018 D 1246995 CDS YP_008733739.1 556565314 17443064 2581641..2582879 1 NC_022657.1 hypothetical protein 2582879 17443064 AFR_11995 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733739.1 2581641 D 1246995 CDS YP_008733740.1 556565315 17443065 2582908..2583594 1 NC_022657.1 hypothetical protein 2583594 17443065 AFR_12000 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733740.1 2582908 D 1246995 CDS YP_008733741.1 556565316 17443066 2583622..2584767 1 NC_022657.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); epoxide hydrolase domain-containing protein 2584767 17443066 AFR_12005 Actinoplanes friuliensis DSM 7358 epoxide hydrolase domain-containing protein YP_008733741.1 2583622 D 1246995 CDS YP_008733742.1 556565317 17443067 complement(2584822..2585196) 1 NC_022657.1 COG3795 Uncharacterized protein conserved in bacteria; YCII-like protein 2585196 17443067 AFR_12010 Actinoplanes friuliensis DSM 7358 YCII-like protein YP_008733742.1 2584822 R 1246995 CDS YP_008733743.1 556565318 17443068 complement(2585290..2586813) 1 NC_022657.1 COG2202 FOG: PAS/PAC domain; putative magnesium/manganese-dependent protein phosphatase 2586813 17443068 AFR_12015 Actinoplanes friuliensis DSM 7358 putative magnesium/manganese-dependent protein phosphatase YP_008733743.1 2585290 R 1246995 CDS YP_008733744.1 556565319 17443069 complement(2586840..2587748) 1 NC_022657.1 COG0840 Methyl-accepting chemotaxis protein; putative methyl-accepting chemotaxis protein 2587748 17443069 AFR_12020 Actinoplanes friuliensis DSM 7358 putative methyl-accepting chemotaxis protein YP_008733744.1 2586840 R 1246995 CDS YP_008733745.1 556565320 17443070 complement(2587745..2588287) 1 NC_022657.1 COG2202 FOG: PAS/PAC domain; hypothetical protein 2588287 17443070 AFR_12025 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733745.1 2587745 R 1246995 CDS YP_008733746.1 556565321 17443071 complement(2588355..2588972) 1 NC_022657.1 cation efflux protein 2588972 17443071 AFR_12030 Actinoplanes friuliensis DSM 7358 cation efflux protein YP_008733746.1 2588355 R 1246995 CDS YP_008733747.1 556565322 17443072 complement(2588972..2589292) 1 NC_022657.1 COG0640 Predicted transcriptional regulators; ArsR family transcriptional regulator 2589292 17443072 AFR_12035 Actinoplanes friuliensis DSM 7358 ArsR family transcriptional regulator YP_008733747.1 2588972 R 1246995 CDS YP_008733748.1 556565323 17443073 complement(2589345..2592077) 1 NC_022657.1 COG1305 Transglutaminase-like enzymes, putative cysteine proteases; transglutaminase domain-containing protein 2592077 17443073 AFR_12040 Actinoplanes friuliensis DSM 7358 transglutaminase domain-containing protein YP_008733748.1 2589345 R 1246995 CDS YP_008733749.1 556565324 17443074 complement(2592071..2593216) 1 NC_022657.1 COG1721 Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain); hypothetical protein 2593216 17443074 AFR_12045 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733749.1 2592071 R 1246995 CDS YP_008733750.1 556565325 17443075 complement(2593213..2594199) 1 NC_022657.1 COG0714 MoxR-like ATPases; MoxR-like ATPase 2594199 17443075 AFR_12050 Actinoplanes friuliensis DSM 7358 MoxR-like ATPase YP_008733750.1 2593213 R 1246995 CDS YP_008733751.1 556565326 17443076 complement(2594210..2596792) 1 NC_022657.1 fibronectin type III domain-containing protein 2596792 17443076 AFR_12055 Actinoplanes friuliensis DSM 7358 fibronectin type III domain-containing protein YP_008733751.1 2594210 R 1246995 CDS YP_008733752.1 556565327 17443077 complement(2596976..2598070) 1 NC_022657.1 hypothetical protein 2598070 17443077 AFR_12060 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733752.1 2596976 R 1246995 CDS YP_008733753.1 556565328 17443079 2598717..2599049 1 NC_022657.1 hypothetical protein 2599049 17443079 AFR_12070 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733753.1 2598717 D 1246995 CDS YP_008733754.1 556565329 17443080 2599688..2600929 1 NC_022657.1 hypothetical protein 2600929 17443080 AFR_12075 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733754.1 2599688 D 1246995 CDS YP_008733755.1 556565330 17443081 2600913..2601908 1 NC_022657.1 COG0714 MoxR-like ATPases; hypothetical protein 2601908 17443081 AFR_12080 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733755.1 2600913 D 1246995 CDS YP_008733756.1 556565331 17443082 complement(2601967..2602383) 1 NC_022657.1 hypothetical protein 2602383 17443082 AFR_12085 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733756.1 2601967 R 1246995 CDS YP_008733757.1 556565332 17443083 2602432..2602854 1 NC_022657.1 hypothetical protein 2602854 17443083 AFR_12090 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733757.1 2602432 D 1246995 CDS YP_008733758.1 556565333 17443084 2602851..2605022 1 NC_022657.1 COG1075 Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold; hypothetical protein 2605022 17443084 AFR_12095 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733758.1 2602851 D 1246995 CDS YP_008733759.1 556565334 17443085 2605042..2605896 1 NC_022657.1 hypothetical protein 2605896 17443085 AFR_12100 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733759.1 2605042 D 1246995 CDS YP_008733760.1 556565335 17443086 2605978..2606490 1 NC_022657.1 hypothetical protein 2606490 17443086 AFR_12105 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733760.1 2605978 D 1246995 CDS YP_008733761.1 556565336 17443087 complement(2606667..2607200) 1 NC_022657.1 hypothetical protein 2607200 17443087 AFR_12110 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733761.1 2606667 R 1246995 CDS YP_008733762.1 556565337 17443088 2607276..2607761 1 NC_022657.1 COG1413 FOG: HEAT repeat; peptidase C14, caspase catalytic subunit p20 2607761 17443088 AFR_12115 Actinoplanes friuliensis DSM 7358 peptidase C14, caspase catalytic subunit p20 YP_008733762.1 2607276 D 1246995 CDS YP_008733763.1 556565338 17443089 complement(2607996..2610851) 1 NC_022657.1 hypothetical protein 2610851 17443089 AFR_12120 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733763.1 2607996 R 1246995 CDS YP_008733764.1 556565339 17443090 complement(2610856..2611080) 1 NC_022657.1 COG1278 Cold shock proteins; CspA family cold shock protein 2611080 17443090 AFR_12125 Actinoplanes friuliensis DSM 7358 CspA family cold shock protein YP_008733764.1 2610856 R 1246995 CDS YP_008733765.1 556565340 17443091 2611287..2611502 1 NC_022657.1 hypothetical protein 2611502 17443091 AFR_12130 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733765.1 2611287 D 1246995 CDS YP_008733766.1 556565341 17443092 complement(2612297..2613205) 1 NC_022657.1 hypothetical protein 2613205 17443092 AFR_12135 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733766.1 2612297 R 1246995 CDS YP_008733767.1 556565342 17443093 complement(2613208..2613546) 1 NC_022657.1 hypothetical protein 2613546 17443093 AFR_12140 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733767.1 2613208 R 1246995 CDS YP_008733768.1 556565343 17443094 complement(2613813..2614568) 1 NC_022657.1 hypothetical protein 2614568 17443094 AFR_12145 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733768.1 2613813 R 1246995 CDS YP_008733769.1 556565344 17443095 2615096..2616292 1 NC_022657.1 hypothetical protein 2616292 17443095 AFR_12150 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733769.1 2615096 D 1246995 CDS YP_008733770.1 556565345 17443096 2616443..2616643 1 NC_022657.1 COG3293 Transposase and inactivated derivatives; transposase 2616643 17443096 AFR_12155 Actinoplanes friuliensis DSM 7358 transposase YP_008733770.1 2616443 D 1246995 CDS YP_008733771.1 556565346 17443097 2616889..2617278 1 NC_022657.1 COG3293 Transposase and inactivated derivatives; transposase 2617278 17443097 AFR_12160 Actinoplanes friuliensis DSM 7358 transposase YP_008733771.1 2616889 D 1246995 CDS YP_008733772.1 556565347 17443098 2617453..2618031 1 NC_022657.1 COG0656 Aldo/keto reductases, related to diketogulonate reductase; hypothetical protein 2618031 17443098 AFR_12165 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733772.1 2617453 D 1246995 CDS YP_008733773.1 556565348 17443099 2618237..2618638 1 NC_022657.1 COG3293 Transposase and inactivated derivatives; transposase 2618638 17443099 AFR_12170 Actinoplanes friuliensis DSM 7358 transposase YP_008733773.1 2618237 D 1246995 CDS YP_008733774.1 556565349 17443100 2618779..2619042 1 NC_022657.1 COG3039 Transposase and inactivated derivatives, IS5 family; transposase 2619042 17443100 AFR_12175 Actinoplanes friuliensis DSM 7358 transposase YP_008733774.1 2618779 D 1246995 CDS YP_008733775.1 556565350 17443101 complement(2620071..2621054) 1 NC_022657.1 COG2207 AraC-type DNA-binding domain-containing proteins; AraC family transcriptional regulator 2621054 17443101 AFR_12180 Actinoplanes friuliensis DSM 7358 AraC family transcriptional regulator YP_008733775.1 2620071 R 1246995 CDS YP_008733776.1 556565351 17443102 2621094..2621828 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); short chain dehydrogenase/reductase family oxidoreductase 2621828 17443102 AFR_12185 Actinoplanes friuliensis DSM 7358 short chain dehydrogenase/reductase family oxidoreductase YP_008733776.1 2621094 D 1246995 CDS YP_008733777.1 556565352 17443103 2624005..2624451 1 NC_022657.1 COG3293 Transposase and inactivated derivatives; transposase 2624451 17443103 AFR_12190 Actinoplanes friuliensis DSM 7358 transposase YP_008733777.1 2624005 D 1246995 CDS YP_008733778.1 556565353 17443104 2624592..2624957 1 NC_022657.1 COG3039 Transposase and inactivated derivatives, IS5 family; transposase 2624957 17443104 AFR_12195 Actinoplanes friuliensis DSM 7358 transposase YP_008733778.1 2624592 D 1246995 CDS YP_008733779.1 556565354 17443105 2625101..2626174 1 NC_022657.1 COG4405 Uncharacterized protein conserved in bacteria; peptidase S51 dipeptidase E 2626174 17443105 AFR_12200 Actinoplanes friuliensis DSM 7358 peptidase S51 dipeptidase E YP_008733779.1 2625101 D 1246995 CDS YP_008733780.1 556565355 17443106 complement(2626171..2626755) 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); short chain dehydrogenase 2626755 17443106 AFR_12205 Actinoplanes friuliensis DSM 7358 short chain dehydrogenase YP_008733780.1 2626171 R 1246995 CDS YP_008733781.1 556565356 17443107 2626795..2627715 1 NC_022657.1 hypothetical protein 2627715 17443107 AFR_12210 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733781.1 2626795 D 1246995 CDS YP_008733782.1 556565357 17443108 2627788..2628111 1 NC_022657.1 hypothetical protein 2628111 17443108 AFR_12215 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733782.1 2627788 D 1246995 CDS YP_008733783.1 556565358 17443109 2628195..2629346 1 NC_022657.1 cellulose 1,4-beta-cellobiosidase 2629346 17443109 AFR_12220 Actinoplanes friuliensis DSM 7358 cellulose 1,4-beta-cellobiosidase YP_008733783.1 2628195 D 1246995 CDS YP_008733784.1 556565359 17443110 2629591..2630103 1 NC_022657.1 hypothetical protein 2630103 17443110 AFR_12225 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733784.1 2629591 D 1246995 CDS YP_008733785.1 556565360 17443111 2630252..2630776 1 NC_022657.1 hypothetical protein 2630776 17443111 AFR_12230 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733785.1 2630252 D 1246995 CDS YP_008733786.1 556565361 17443112 2631449..2631853 1 NC_022657.1 COG2085 Predicted dinucleotide-binding enzymes; coenzyme F420-dependent NADP oxidoreductase 2631853 17443112 AFR_12235 Actinoplanes friuliensis DSM 7358 coenzyme F420-dependent NADP oxidoreductase YP_008733786.1 2631449 D 1246995 CDS YP_008733787.1 556565362 17443113 2631920..2632324 1 NC_022657.1 COG3467 Predicted flavin-nucleotide-binding protein; pyridoxamine 5'-phosphate oxidase-like FMN-binding protein 2632324 17443113 AFR_12240 Actinoplanes friuliensis DSM 7358 pyridoxamine 5'-phosphate oxidase-like FMN-binding protein YP_008733787.1 2631920 D 1246995 CDS YP_008733788.1 556565363 17443114 complement(2632538..2633557) 1 NC_022657.1 COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases); aldoketoreductase 2633557 17443114 AFR_12245 Actinoplanes friuliensis DSM 7358 aldoketoreductase YP_008733788.1 2632538 R 1246995 CDS YP_008733789.1 556565364 17443115 complement(2633741..2634151) 1 NC_022657.1 COG3592 Uncharacterized conserved protein; hypothetical protein 2634151 17443115 AFR_12250 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733789.1 2633741 R 1246995 CDS YP_008733790.1 556565365 17443116 complement(2634144..2634470) 1 NC_022657.1 COG2388 Predicted acetyltransferase; hypothetical protein 2634470 17443116 AFR_12255 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733790.1 2634144 R 1246995 CDS YP_008733791.1 556565366 17443117 2634696..2635349 1 NC_022657.1 hypothetical protein 2635349 17443117 AFR_12260 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733791.1 2634696 D 1246995 CDS YP_008733792.1 556565367 17443118 2635543..2635788 1 NC_022657.1 Luciferase-like, subgroup 2635788 17443118 AFR_12265 Actinoplanes friuliensis DSM 7358 Luciferase-like, subgroup YP_008733792.1 2635543 D 1246995 CDS YP_008733793.1 556565368 17443119 complement(2635745..2637397) 1 NC_022657.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); hydrolase 2637397 17443119 AFR_12270 Actinoplanes friuliensis DSM 7358 hydrolase YP_008733793.1 2635745 R 1246995 CDS YP_008733794.1 556565369 17443120 complement(2637544..2638296) 1 NC_022657.1 COG0789 Predicted transcriptional regulators; MerR family transcriptional regulator 2638296 17443120 AFR_12275 Actinoplanes friuliensis DSM 7358 MerR family transcriptional regulator YP_008733794.1 2637544 R 1246995 CDS YP_008733795.1 556565370 17443121 2638570..2641311 1 NC_022657.1 COG3899 Predicted ATPase; LuxR family transcriptional regulator 2641311 17443121 AFR_12280 Actinoplanes friuliensis DSM 7358 LuxR family transcriptional regulator YP_008733795.1 2638570 D 1246995 CDS YP_008733796.1 556565371 17443122 2642228..2643190 1 NC_022657.1 COG4585 Signal transduction histidine kinase; histidine kinase-, DNA gyrase B-, and HSP90-like ATPase family protein 2643190 17443122 AFR_12285 Actinoplanes friuliensis DSM 7358 histidine kinase-, DNA gyrase B-, and HSP90-like ATPase family protein YP_008733796.1 2642228 D 1246995 CDS YP_008733797.1 556565372 17443123 complement(2643288..2643677) 1 NC_022657.1 COG3837 Uncharacterized conserved protein, contains double-stranded beta-helix domain; hypothetical protein 2643677 17443123 AFR_12290 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733797.1 2643288 R 1246995 CDS YP_008733798.1 556565373 17443124 complement(2644168..2645076) 1 NC_022657.1 COG1073 Hydrolases of the alpha/beta superfamily; dienelactone hydrolase domain-containing protein 2645076 17443124 AFR_12295 Actinoplanes friuliensis DSM 7358 dienelactone hydrolase domain-containing protein YP_008733798.1 2644168 R 1246995 CDS YP_008733799.1 556565374 17443125 2645205..2645393 1 NC_022657.1 hypothetical protein 2645393 17443125 AFR_12300 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733799.1 2645205 D 1246995 CDS YP_008733800.1 556565375 17443126 complement(2645594..2646766) 1 NC_022657.1 COG4292 Predicted membrane protein; hypothetical protein 2646766 17443126 AFR_12305 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733800.1 2645594 R 1246995 CDS YP_008733801.1 556565376 17443127 2647169..2648047 1 NC_022657.1 COG1266 Predicted metal-dependent membrane protease; abortive infection protein 2648047 17443127 AFR_12310 Actinoplanes friuliensis DSM 7358 abortive infection protein YP_008733801.1 2647169 D 1246995 CDS YP_008733802.1 556565377 17443128 2648272..2648529 1 NC_022657.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); hypothetical protein 2648529 17443128 AFR_12315 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733802.1 2648272 D 1246995 CDS YP_008733803.1 556565378 17443129 2648848..2649129 1 NC_022657.1 hypothetical protein 2649129 17443129 AFR_12320 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733803.1 2648848 D 1246995 CDS YP_008733804.1 556565379 17443130 2649425..2652169 1 NC_022657.1 COG2771 DNA-binding HTH domain-containing proteins; LuxR family transcriptional regulator 2652169 17443130 AFR_12325 Actinoplanes friuliensis DSM 7358 LuxR family transcriptional regulator YP_008733804.1 2649425 D 1246995 CDS YP_008733805.1 556565380 17443131 complement(2652176..2652859) 1 NC_022657.1 hypothetical protein 2652859 17443131 AFR_12330 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733805.1 2652176 R 1246995 CDS YP_008733806.1 556565381 17443132 2653132..2653542 1 NC_022657.1 hypothetical protein 2653542 17443132 AFR_12335 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733806.1 2653132 D 1246995 CDS YP_008733807.1 556565382 17443133 complement(2653649..2654386) 1 NC_022657.1 COG0789 Predicted transcriptional regulators; MerR family transcriptional regulator 2654386 17443133 AFR_12340 Actinoplanes friuliensis DSM 7358 MerR family transcriptional regulator YP_008733807.1 2653649 R 1246995 CDS YP_008733808.1 556565383 17443134 2654730..2654960 1 NC_022657.1 hypothetical protein 2654960 17443134 AFR_12345 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733808.1 2654730 D 1246995 CDS YP_008733809.1 556565384 17443135 2655074..2656108 1 NC_022657.1 COG0666 FOG: Ankyrin repeat; ankyrin 2656108 17443135 AFR_12350 Actinoplanes friuliensis DSM 7358 ankyrin YP_008733809.1 2655074 D 1246995 CDS YP_008733810.1 556565385 17443136 2656110..2657231 1 NC_022657.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); epoxide hydrolase 1 2657231 17443136 AFR_12355 Actinoplanes friuliensis DSM 7358 epoxide hydrolase 1 YP_008733810.1 2656110 D 1246995 CDS YP_008733811.1 556565386 17443137 2657426..2658091 1 NC_022657.1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; LuxR family transcriptional regulator 2658091 17443137 AFR_12360 Actinoplanes friuliensis DSM 7358 LuxR family transcriptional regulator YP_008733811.1 2657426 D 1246995 CDS YP_008733812.1 556565387 17443138 complement(2658273..2659445) 1 NC_022657.1 COG2208 Serine phosphatase RsbU, regulator of sigma subunit; putative magnesium/manganese-dependent protein phosphatase 2659445 17443138 AFR_12365 Actinoplanes friuliensis DSM 7358 putative magnesium/manganese-dependent protein phosphatase YP_008733812.1 2658273 R 1246995 CDS YP_008733813.1 556565388 17443139 complement(2659636..2660499) 1 NC_022657.1 cytochrome c biogenesis protein, transmembrane region 2660499 17443139 AFR_12370 Actinoplanes friuliensis DSM 7358 cytochrome c biogenesis protein, transmembrane region YP_008733813.1 2659636 R 1246995 CDS YP_008733814.1 556565389 17443140 complement(2660504..2660971) 1 NC_022657.1 COG0526 Thiol-disulfide isomerase and thioredoxins; redoxin domain-containing protein 2660971 17443140 AFR_12375 Actinoplanes friuliensis DSM 7358 redoxin domain-containing protein YP_008733814.1 2660504 R 1246995 CDS YP_008733815.1 556565390 17443141 complement(2661261..2663420) 1 NC_022657.1 COG0376 Catalase (peroxidase I); catalase/hydroperoxidase HPI(I) 2663420 17443141 AFR_12380 Actinoplanes friuliensis DSM 7358 catalase/hydroperoxidase HPI(I) YP_008733815.1 2661261 R 1246995 CDS YP_008733816.1 556565391 17443142 complement(2663645..2664364) 1 NC_022657.1 COG0580 Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family); major intrinsic protein 2664364 17443142 AFR_12385 Actinoplanes friuliensis DSM 7358 major intrinsic protein YP_008733816.1 2663645 R 1246995 CDS YP_008733817.1 556565392 17443143 complement(2664656..2665423) 1 NC_022657.1 COG5662 Predicted transmembrane transcriptional regulator (anti-sigma factor); putative transmembrane anti-sigma factor 2665423 17443143 AFR_12390 Actinoplanes friuliensis DSM 7358 putative transmembrane anti-sigma factor YP_008733817.1 2664656 R 1246995 CDS YP_008733818.1 556565393 17443144 complement(2665420..2665827) 1 NC_022657.1 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; ECF subfamily RNA polymerase sigma-24 factor 2665827 17443144 AFR_12395 Actinoplanes friuliensis DSM 7358 ECF subfamily RNA polymerase sigma-24 factor YP_008733818.1 2665420 R 1246995 CDS YP_008733819.1 556565394 17443145 2666607..2668184 1 NC_022657.1 COG2730 Endoglucanase; putative glycosyl hydrolase 2668184 17443145 AFR_12400 Actinoplanes friuliensis DSM 7358 putative glycosyl hydrolase YP_008733819.1 2666607 D 1246995 CDS YP_008733820.1 556565395 17443146 2668748..2670031 1 NC_022657.1 COG1680 Beta-lactamase class C and other penicillin binding proteins; beta-lactamase 2670031 17443146 AFR_12405 Actinoplanes friuliensis DSM 7358 beta-lactamase YP_008733820.1 2668748 D 1246995 CDS YP_008733821.1 556565396 17443147 2670298..2680179 1 NC_022657.1 COG1020 Non-ribosomal peptide synthetase modules and related proteins; amino acid adenylation protein 2680179 17443147 AFR_12410 Actinoplanes friuliensis DSM 7358 amino acid adenylation protein YP_008733821.1 2670298 D 1246995 CDS YP_008733822.1 556565397 17443148 2680139..2700052 1 NC_022657.1 COG1020 Non-ribosomal peptide synthetase modules and related proteins; amino acid adenylation protein 2700052 17443148 AFR_12415 Actinoplanes friuliensis DSM 7358 amino acid adenylation protein YP_008733822.1 2680139 D 1246995 CDS YP_008733823.1 556565398 17443149 2700049..2701272 1 NC_022657.1 COG0477 Permeases of the major facilitator superfamily; major facilitator superfamily protein 2701272 17443149 AFR_12420 Actinoplanes friuliensis DSM 7358 major facilitator superfamily protein YP_008733823.1 2700049 D 1246995 CDS YP_008733824.1 556565399 17443150 2701299..2701511 1 NC_022657.1 COG3251 Uncharacterized protein conserved in bacteria; MbtH domain-containing protein 2701511 17443150 AFR_12425 Actinoplanes friuliensis DSM 7358 MbtH domain-containing protein YP_008733824.1 2701299 D 1246995 CDS YP_008733825.1 556565400 17443151 complement(2701590..2701973) 1 NC_022657.1 hypothetical protein 2701973 17443151 AFR_12430 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733825.1 2701590 R 1246995 CDS YP_008733826.1 556565401 17443152 2702195..2703469 1 NC_022657.1 COG4585 Signal transduction histidine kinase; histidine kinase-, DNA gyrase B-, and HSP90-like ATPase family protein 2703469 17443152 AFR_12435 Actinoplanes friuliensis DSM 7358 histidine kinase-, DNA gyrase B-, and HSP90-like ATPase family protein YP_008733826.1 2702195 D 1246995 CDS YP_008733827.1 556565402 17443153 2703469..2704170 1 NC_022657.1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; LuxR family transcriptional regulator 2704170 17443153 AFR_12440 Actinoplanes friuliensis DSM 7358 LuxR family transcriptional regulator YP_008733827.1 2703469 D 1246995 CDS YP_008733828.1 556565403 17443154 2704487..2705233 1 NC_022657.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); alpha/beta hydrolase fold protein 2705233 17443154 AFR_12445 Actinoplanes friuliensis DSM 7358 alpha/beta hydrolase fold protein YP_008733828.1 2704487 D 1246995 CDS YP_008733829.1 556565404 17443155 2705511..2706527 1 NC_022657.1 COG0840 Methyl-accepting chemotaxis protein; hypothetical protein 2706527 17443155 AFR_12450 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733829.1 2705511 D 1246995 CDS YP_008733830.1 556565405 17443156 2706793..2707248 1 NC_022657.1 hypothetical protein 2707248 17443156 AFR_12455 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733830.1 2706793 D 1246995 CDS YP_008733831.1 556565406 17443157 complement(2707382..2708833) 1 NC_022657.1 COG0699 Predicted GTPases (dynamin-related); hypothetical protein 2708833 17443157 AFR_12460 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733831.1 2707382 R 1246995 CDS YP_008733832.1 556565407 17443158 complement(2708830..2710788) 1 NC_022657.1 COG0699 Predicted GTPases (dynamin-related); HSR1-like GTP-binding protein 2710788 17443158 AFR_12465 Actinoplanes friuliensis DSM 7358 HSR1-like GTP-binding protein YP_008733832.1 2708830 R 1246995 CDS YP_008733833.1 556565408 17443159 complement(2710814..2711656) 1 NC_022657.1 hypothetical protein 2711656 17443159 AFR_12470 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733833.1 2710814 R 1246995 CDS YP_008733834.1 556565409 17443160 2711876..2712931 1 NC_022657.1 molecular chaperone DnaK 2712931 17443160 AFR_12475 Actinoplanes friuliensis DSM 7358 molecular chaperone DnaK YP_008733834.1 2711876 D 1246995 CDS YP_008733835.1 556565410 17443161 2712928..2715489 1 NC_022657.1 COG2771 DNA-binding HTH domain-containing proteins; LuxR family transcriptional regulator 2715489 17443161 AFR_12480 Actinoplanes friuliensis DSM 7358 LuxR family transcriptional regulator YP_008733835.1 2712928 D 1246995 CDS YP_008733836.1 556565411 17443162 2715486..2717123 1 NC_022657.1 COG0642 Signal transduction histidine kinase; ATP-binding region ATPase domain-containing protein 2717123 17443162 AFR_12485 Actinoplanes friuliensis DSM 7358 ATP-binding region ATPase domain-containing protein YP_008733836.1 2715486 D 1246995 CDS YP_008733837.1 556565412 17443163 2717120..2717476 1 NC_022657.1 COG0640 Predicted transcriptional regulators; hypothetical protein 2717476 17443163 AFR_12490 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733837.1 2717120 D 1246995 CDS YP_008733838.1 556565413 17443164 2717494..2718243 1 NC_022657.1 activator of hsp90 ATPase 1 family protein 2718243 17443164 AFR_12495 Actinoplanes friuliensis DSM 7358 activator of hsp90 ATPase 1 family protein YP_008733838.1 2717494 D 1246995 CDS YP_008733839.1 556565414 17443165 2718274..2719413 1 NC_022657.1 COG3177 Uncharacterized conserved protein; hypothetical protein 2719413 17443165 AFR_12500 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733839.1 2718274 D 1246995 CDS YP_008733840.1 556565415 17443166 complement(2719596..2720264) 1 NC_022657.1 hypothetical protein 2720264 17443166 AFR_12505 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733840.1 2719596 R 1246995 CDS YP_008733841.1 556565416 17443167 complement(2720497..2721156) 1 NC_022657.1 hypothetical protein 2721156 17443167 AFR_12510 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733841.1 2720497 R 1246995 CDS YP_008733842.1 556565417 17443168 complement(2721366..2722973) 1 NC_022657.1 COG2203 FOG: GAF domain; putative multi-sensor signal transduction histidine kinase 2722973 17443168 AFR_12515 Actinoplanes friuliensis DSM 7358 putative multi-sensor signal transduction histidine kinase YP_008733842.1 2721366 R 1246995 CDS YP_008733843.1 556565418 17443169 complement(2723088..2723894) 1 NC_022657.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); hypothetical protein 2723894 17443169 AFR_12520 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733843.1 2723088 R 1246995 CDS YP_008733844.1 556565419 17443170 complement(2723929..2724594) 1 NC_022657.1 hypothetical protein 2724594 17443170 AFR_12525 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733844.1 2723929 R 1246995 CDS YP_008733845.1 556565420 17443171 2724822..2725556 1 NC_022657.1 COG2826 Transposase and inactivated derivatives, IS30 family; hypothetical protein 2725556 17443171 AFR_12530 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733845.1 2724822 D 1246995 CDS YP_008733846.1 556565421 17443172 2725608..2725877 1 NC_022657.1 putative transcriptional regulator 2725877 17443172 AFR_12535 Actinoplanes friuliensis DSM 7358 putative transcriptional regulator YP_008733846.1 2725608 D 1246995 CDS YP_008733847.1 556565422 17443173 complement(2726067..2726753) 1 NC_022657.1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; two-component system response regulator 2726753 17443173 AFR_12540 Actinoplanes friuliensis DSM 7358 two-component system response regulator YP_008733847.1 2726067 R 1246995 CDS YP_008733848.1 556565423 17443174 complement(2726750..2727910) 1 NC_022657.1 COG4585 Signal transduction histidine kinase; two-component system histidine kinase 2727910 17443174 AFR_12545 Actinoplanes friuliensis DSM 7358 two-component system histidine kinase YP_008733848.1 2726750 R 1246995 CDS YP_008733849.1 556565424 17443175 2727997..2729994 1 NC_022657.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); alpha/beta fold family hydrolase 2729994 17443175 AFR_12550 Actinoplanes friuliensis DSM 7358 alpha/beta fold family hydrolase YP_008733849.1 2727997 D 1246995 CDS YP_008733850.1 556565425 17443176 complement(2730055..2731623) 1 NC_022657.1 ricin b lectin 2731623 17443176 AFR_12555 Actinoplanes friuliensis DSM 7358 ricin b lectin YP_008733850.1 2730055 R 1246995 CDS YP_008733851.1 556565426 17443177 complement(2731764..2732504) 1 NC_022657.1 ABC-2 type transporter 2732504 17443177 AFR_12560 Actinoplanes friuliensis DSM 7358 ABC-2 type transporter YP_008733851.1 2731764 R 1246995 CDS YP_008733852.1 556565427 17443178 complement(2732506..2733423) 1 NC_022657.1 COG1131 ABC-type multidrug transport system, ATPase component; ABC transporter ATP-binding protein 2733423 17443178 AFR_12565 Actinoplanes friuliensis DSM 7358 ABC transporter ATP-binding protein YP_008733852.1 2732506 R 1246995 CDS YP_008733853.1 556565428 17443179 complement(2733464..2734231) 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); oxidoreductase 2734231 17443179 AFR_12570 Actinoplanes friuliensis DSM 7358 oxidoreductase YP_008733853.1 2733464 R 1246995 CDS YP_008733854.1 556565429 17443180 complement(2734336..2735706) 1 NC_022657.1 COG1012 NAD-dependent aldehyde dehydrogenases; aldehyde dehydrogenase 2735706 17443180 AFR_12575 Actinoplanes friuliensis DSM 7358 aldehyde dehydrogenase YP_008733854.1 2734336 R 1246995 CDS YP_008733855.1 556565430 17443181 complement(2735703..2736572) 1 NC_022657.1 COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway); putative fumarylacetoacetate hydrolase family protein 2736572 17443181 AFR_12580 Actinoplanes friuliensis DSM 7358 putative fumarylacetoacetate hydrolase family protein YP_008733855.1 2735703 R 1246995 CDS YP_008733856.1 556565431 17443182 2736683..2737453 1 NC_022657.1 COG1414 Transcriptional regulator; putative IclR-family transcriptional regulator 2737453 17443182 AFR_12585 Actinoplanes friuliensis DSM 7358 putative IclR-family transcriptional regulator YP_008733856.1 2736683 D 1246995 CDS YP_008733857.1 556565432 17443183 2737693..2739129 1 NC_022657.1 COG1653 ABC-type sugar transport system, periplasmic component; putative ABC transporter substrate-binding protein 2739129 17443183 AFR_12590 Actinoplanes friuliensis DSM 7358 putative ABC transporter substrate-binding protein YP_008733857.1 2737693 D 1246995 CDS YP_008733858.1 556565433 17443184 2739264..2741138 1 NC_022657.1 COG1175 ABC-type sugar transport systems, permease components; ABC transporter permease 2741138 17443184 AFR_12595 Actinoplanes friuliensis DSM 7358 ABC transporter permease YP_008733858.1 2739264 D 1246995 CDS YP_008733859.1 556565434 17443185 2741206..2741724 1 NC_022657.1 hypothetical protein 2741724 17443185 AFR_12600 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733859.1 2741206 D 1246995 CDS YP_008733860.1 556565435 17443186 complement(2741737..2742570) 1 NC_022657.1 COG1396 Predicted transcriptional regulators; Helix-turn-helix protein 2742570 17443186 AFR_12605 Actinoplanes friuliensis DSM 7358 Helix-turn-helix protein YP_008733860.1 2741737 R 1246995 CDS YP_008733861.1 556565436 17443187 2742740..2743660 1 NC_022657.1 COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases; alcohol dehydrogenase zinc-binding domain-containing protein 2743660 17443187 AFR_12610 Actinoplanes friuliensis DSM 7358 alcohol dehydrogenase zinc-binding domain-containing protein YP_008733861.1 2742740 D 1246995 CDS YP_008733862.1 556565437 17443188 complement(2743698..2744750) 1 NC_022657.1 COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases; alcohol dehydrogenase superfamily protein 2744750 17443188 AFR_12615 Actinoplanes friuliensis DSM 7358 alcohol dehydrogenase superfamily protein YP_008733862.1 2743698 R 1246995 CDS YP_008733863.1 556565438 17443189 2745027..2745413 1 NC_022657.1 COG1846 Transcriptional regulators; MarR family transcriptional regulator 2745413 17443189 AFR_12620 Actinoplanes friuliensis DSM 7358 MarR family transcriptional regulator YP_008733863.1 2745027 D 1246995 CDS YP_008733864.1 556565439 17443190 2745466..2746272 1 NC_022657.1 COG0682 Prolipoprotein diacylglyceryltransferase; putative prolipoprotein diacylglyceryl transferase 2746272 17443190 AFR_12625 Actinoplanes friuliensis DSM 7358 putative prolipoprotein diacylglyceryl transferase YP_008733864.1 2745466 D 1246995 CDS YP_008733865.1 556565440 17443191 2746290..2747609 1 NC_022657.1 COG4097 Predicted ferric reductase; Membrane flavodoxin oxidoreductase 2747609 17443191 AFR_12630 Actinoplanes friuliensis DSM 7358 Membrane flavodoxin oxidoreductase YP_008733865.1 2746290 D 1246995 CDS YP_008733866.1 556565441 17443192 2748280..2748864 1 NC_022657.1 COG1309 Transcriptional regulator; TetR family transcriptional regulator 2748864 17443192 AFR_12635 Actinoplanes friuliensis DSM 7358 TetR family transcriptional regulator YP_008733866.1 2748280 D 1246995 CDS YP_008733867.1 556565442 17443193 2748861..2749229 1 NC_022657.1 hypothetical protein 2749229 17443193 AFR_12640 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733867.1 2748861 D 1246995 CDS YP_008733868.1 556565443 17443194 2749280..2749906 1 NC_022657.1 COG0262 Dihydrofolate reductase; hypothetical protein 2749906 17443194 AFR_12645 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733868.1 2749280 D 1246995 CDS YP_008733869.1 556565444 17443195 complement(2749946..2750908) 1 NC_022657.1 COG2378 Predicted transcriptional regulator; DeoR family transcriptional regulator 2750908 17443195 AFR_12650 Actinoplanes friuliensis DSM 7358 DeoR family transcriptional regulator YP_008733869.1 2749946 R 1246995 CDS YP_008733870.1 556565445 17443196 2751017..2751478 1 NC_022657.1 COG2764 Uncharacterized protein conserved in bacteria; hypothetical protein 2751478 17443196 AFR_12655 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733870.1 2751017 D 1246995 CDS YP_008733871.1 556565446 17443197 complement(2751563..2752828) 1 NC_022657.1 COG1520 FOG: WD40-like repeat; hypothetical protein 2752828 17443197 AFR_12660 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733871.1 2751563 R 1246995 CDS YP_008733872.1 556565447 17443198 2753003..2753335 1 NC_022657.1 hypothetical protein 2753335 17443198 AFR_12665 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733872.1 2753003 D 1246995 CDS YP_008733873.1 556565448 17443199 complement(2753344..2753928) 1 NC_022657.1 COG1418 Predicted HD superfamily hydrolase; hypothetical protein 2753928 17443199 AFR_12670 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733873.1 2753344 R 1246995 CDS YP_008733874.1 556565449 17443200 2754112..2754450 1 NC_022657.1 hypothetical protein 2754450 17443200 AFR_12675 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733874.1 2754112 D 1246995 CDS YP_008733875.1 556565450 17443201 complement(2754455..2755369) 1 NC_022657.1 COG3315 O-Methyltransferase involved in polyketide biosynthesis; methyltransferase 2755369 17443201 AFR_12680 Actinoplanes friuliensis DSM 7358 methyltransferase YP_008733875.1 2754455 R 1246995 CDS YP_008733876.1 556565451 17443202 complement(2755483..2755839) 1 NC_022657.1 hypothetical protein 2755839 17443202 AFR_12685 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733876.1 2755483 R 1246995 CDS YP_008733877.1 556565452 17443203 complement(2755832..2757202) 1 NC_022657.1 hypothetical protein 2757202 17443203 AFR_12690 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733877.1 2755832 R 1246995 CDS YP_008733878.1 556565453 17443204 complement(2757276..2758187) 1 NC_022657.1 COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases; phosphoglycerate dehydrogenase 2758187 17443204 AFR_12695 Actinoplanes friuliensis DSM 7358 phosphoglycerate dehydrogenase YP_008733878.1 2757276 R 1246995 CDS YP_008733879.1 556565454 17443205 complement(2758202..2759473) 1 NC_022657.1 COG0477 Permeases of the major facilitator superfamily; major facilitator transporter 2759473 17443205 AFR_12700 Actinoplanes friuliensis DSM 7358 major facilitator transporter YP_008733879.1 2758202 R 1246995 CDS YP_008733880.1 556565455 17443206 2759540..2760259 1 NC_022657.1 COG1802 Transcriptional regulators; GntR family transcriptional regulator 2760259 17443206 AFR_12705 Actinoplanes friuliensis DSM 7358 GntR family transcriptional regulator YP_008733880.1 2759540 D 1246995 CDS YP_008733881.1 556565456 17443207 2760256..2761338 1 NC_022657.1 COG0473 Isocitrate/isopropylmalate dehydrogenase; tartrate dehydrogenase 2761338 17443207 AFR_12710 Actinoplanes friuliensis DSM 7358 tartrate dehydrogenase YP_008733881.1 2760256 D 1246995 CDS YP_008733882.1 556565457 17443208 complement(2761441..2762361) 1 NC_022657.1 COG2207 AraC-type DNA-binding domain-containing proteins; AraC family transcriptional regulator 2762361 17443208 AFR_12715 Actinoplanes friuliensis DSM 7358 AraC family transcriptional regulator YP_008733882.1 2761441 R 1246995 CDS YP_008733883.1 556565458 17443209 2762462..2763427 1 NC_022657.1 COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases; Zn-dependent oxidoreductase 2763427 17443209 AFR_12720 Actinoplanes friuliensis DSM 7358 Zn-dependent oxidoreductase YP_008733883.1 2762462 D 1246995 CDS YP_008733884.1 556565459 17443210 2763812..2764000 1 NC_022657.1 hypothetical protein 2764000 17443210 AFR_12725 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733884.1 2763812 D 1246995 CDS YP_008733885.1 556565460 17443211 complement(2763997..2764116) 1 NC_022657.1 COG1943 Transposase and inactivated derivatives; transposase 2764116 17443211 AFR_12730 Actinoplanes friuliensis DSM 7358 transposase YP_008733885.1 2763997 R 1246995 CDS YP_008733886.1 556565461 17443212 2764225..2765454 1 NC_022657.1 COG0675 Transposase and inactivated derivatives; transposase, IS605 OrfB family protein 2765454 17443212 AFR_12735 Actinoplanes friuliensis DSM 7358 transposase, IS605 OrfB family protein YP_008733886.1 2764225 D 1246995 CDS YP_008733887.1 556565462 17443213 2765880..2766674 1 NC_022657.1 COG0500 SAM-dependent methyltransferases; type 11 methyltransferase 2766674 17443213 AFR_12740 Actinoplanes friuliensis DSM 7358 type 11 methyltransferase YP_008733887.1 2765880 D 1246995 CDS YP_008733888.1 556565463 17443214 complement(2766746..2767270) 1 NC_022657.1 COG3509 Poly(3-hydroxybutyrate) depolymerase; hypothetical protein 2767270 17443214 AFR_12745 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733888.1 2766746 R 1246995 CDS YP_008733889.1 556565464 17443215 2767671..2768237 1 NC_022657.1 COG1309 Transcriptional regulator; TetR family transcriptional regulator 2768237 17443215 AFR_12750 Actinoplanes friuliensis DSM 7358 TetR family transcriptional regulator YP_008733889.1 2767671 D 1246995 CDS YP_008733890.1 556565465 17443216 complement(2768318..2769061) 1 NC_022657.1 antibiotic biosynthesis monooxygenase 2769061 17443216 AFR_12755 Actinoplanes friuliensis DSM 7358 antibiotic biosynthesis monooxygenase YP_008733890.1 2768318 R 1246995 CDS YP_008733891.1 556565466 17443217 2769140..2769769 1 NC_022657.1 COG1309 Transcriptional regulator; Transcriptional regulator, AcrR-family protein 2769769 17443217 AFR_12760 Actinoplanes friuliensis DSM 7358 Transcriptional regulator, AcrR-family protein YP_008733891.1 2769140 D 1246995 CDS YP_008733892.1 556565467 17443218 complement(2769797..2770453) 1 NC_022657.1 COG2159 Predicted metal-dependent hydrolase of the TIM-barrel fold; putative amidohydrolase/decarboxylase 2770453 17443218 AFR_12765 Actinoplanes friuliensis DSM 7358 putative amidohydrolase/decarboxylase YP_008733892.1 2769797 R 1246995 CDS YP_008733893.1 556565468 17443219 complement(2770500..2771363) 1 NC_022657.1 COG1396 Predicted transcriptional regulators; helix-turn-helix domain-containing protein 2771363 17443219 AFR_12770 Actinoplanes friuliensis DSM 7358 helix-turn-helix domain-containing protein YP_008733893.1 2770500 R 1246995 CDS YP_008733894.1 556565469 17443220 2771495..2772334 1 NC_022657.1 COG0702 Predicted nucleoside-diphosphate-sugar epimerases; NmrA family protein 2772334 17443220 AFR_12775 Actinoplanes friuliensis DSM 7358 NmrA family protein YP_008733894.1 2771495 D 1246995 CDS YP_008733895.1 556565470 17443221 2772494..2773027 1 NC_022657.1 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; sigma-70 family RNA polymerase 2773027 17443221 AFR_12780 Actinoplanes friuliensis DSM 7358 sigma-70 family RNA polymerase YP_008733895.1 2772494 D 1246995 CDS YP_008733896.1 556565471 17443222 2773024..2773827 1 NC_022657.1 integral membrane protein 2773827 17443222 AFR_12785 Actinoplanes friuliensis DSM 7358 integral membrane protein YP_008733896.1 2773024 D 1246995 CDS YP_008733897.1 556565472 17443223 2773869..2774666 1 NC_022657.1 COG1131 ABC-type multidrug transport system, ATPase component; ABC transporter-like protein 2774666 17443223 AFR_12790 Actinoplanes friuliensis DSM 7358 ABC transporter-like protein YP_008733897.1 2773869 D 1246995 CDS YP_008733898.1 556565473 17443224 2774663..2776009 1 NC_022657.1 hypothetical protein 2776009 17443224 AFR_12795 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733898.1 2774663 D 1246995 CDS YP_008733899.1 556565474 17443225 2776006..2776623 1 NC_022657.1 hypothetical protein 2776623 17443225 AFR_12800 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733899.1 2776006 D 1246995 CDS YP_008733900.1 556565475 17443226 complement(2776632..2777300) 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); short chain dehydrogenase 2777300 17443226 AFR_12805 Actinoplanes friuliensis DSM 7358 short chain dehydrogenase YP_008733900.1 2776632 R 1246995 CDS YP_008733901.1 556565476 17443227 2777425..2777910 1 NC_022657.1 COG1309 Transcriptional regulator; TetR family transcriptional regulator 2777910 17443227 AFR_12810 Actinoplanes friuliensis DSM 7358 TetR family transcriptional regulator YP_008733901.1 2777425 D 1246995 CDS YP_008733902.1 556565477 17443228 2778068..2779138 1 NC_022657.1 COG0392 Predicted integral membrane protein; hypothetical protein 2779138 17443228 AFR_12815 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733902.1 2778068 D 1246995 CDS YP_008733903.1 556565478 17443229 2779173..2779625 1 NC_022657.1 hypothetical protein 2779625 17443229 AFR_12820 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733903.1 2779173 D 1246995 CDS YP_008733904.1 556565479 17443230 complement(2779666..2780280) 1 NC_022657.1 COG1309 Transcriptional regulator; TetR family transcriptional regulator 2780280 17443230 AFR_12825 Actinoplanes friuliensis DSM 7358 TetR family transcriptional regulator YP_008733904.1 2779666 R 1246995 CDS YP_008733905.1 556565480 17443231 2780366..2781859 1 NC_022657.1 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases; hypothetical protein 2781859 17443231 AFR_12830 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733905.1 2780366 D 1246995 CDS YP_008733906.1 556565481 17443232 complement(2781882..2783291) 1 NC_022657.1 COG3940 Predicted beta-xylosidase; alpha-N-arabinofuranosidase 2783291 17443232 AFR_12835 Actinoplanes friuliensis DSM 7358 alpha-N-arabinofuranosidase YP_008733906.1 2781882 R 1246995 CDS YP_008733907.1 556565482 17443233 2783523..2786069 1 NC_022657.1 hypothetical protein 2786069 17443233 AFR_12840 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733907.1 2783523 D 1246995 CDS YP_008733908.1 556565483 17443234 complement(2786124..2788520) 1 NC_022657.1 COG1554 Trehalose and maltose hydrolases (possible phosphorylases); Kojibiose phosphorylase 2788520 17443234 AFR_12845 Actinoplanes friuliensis DSM 7358 Kojibiose phosphorylase YP_008733908.1 2786124 R 1246995 CDS YP_008733909.1 556565484 17443235 complement(2788492..2790576) 1 NC_022657.1 COG0465 ATP-dependent Zn proteases; ATP-dependent metalloprotease FtsH 2790576 17443235 AFR_12850 Actinoplanes friuliensis DSM 7358 ATP-dependent metalloprotease FtsH YP_008733909.1 2788492 R 1246995 CDS YP_008733910.1 556565485 17443236 complement(2790582..2790884) 1 NC_022657.1 ethyl tert-butyl ether degradation protein EthD 2790884 17443236 AFR_12855 Actinoplanes friuliensis DSM 7358 ethyl tert-butyl ether degradation protein EthD YP_008733910.1 2790582 R 1246995 CDS YP_008733911.1 556565486 17443237 complement(2791020..2792498) 1 NC_022657.1 hypothetical protein 2792498 17443237 AFR_12860 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733911.1 2791020 R 1246995 CDS YP_008733912.1 556565487 17443238 complement(2792495..2792842) 1 NC_022657.1 COG1695 Predicted transcriptional regulators; Coproporphyrinogen 3 oxidase, aerobic 2792842 17443238 AFR_12865 Actinoplanes friuliensis DSM 7358 Coproporphyrinogen 3 oxidase, aerobic YP_008733912.1 2792495 R 1246995 CDS YP_008733913.1 556565488 17443239 complement(2792938..2794635) 1 NC_022657.1 COG0785 Cytochrome c biogenesis protein; alkyl hydroperoxide reductase/ thiol specific antioxidant/ Mal allergen 2794635 17443239 AFR_12870 Actinoplanes friuliensis DSM 7358 alkyl hydroperoxide reductase/ thiol specific antioxidant/ Mal allergen YP_008733913.1 2792938 R 1246995 CDS YP_008733914.1 556565489 17443240 complement(2794704..2795804) 1 NC_022657.1 COG1960 Acyl-CoA dehydrogenases; acyl-CoA dehydrogenase 2795804 17443240 AFR_12875 Actinoplanes friuliensis DSM 7358 acyl-CoA dehydrogenase YP_008733914.1 2794704 R 1246995 CDS YP_008733915.1 556565490 17443241 complement(2795886..2796794) 1 NC_022657.1 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; ECF subfamily RNA polymerase sigma-24 subunit 2796794 17443241 AFR_12880 Actinoplanes friuliensis DSM 7358 ECF subfamily RNA polymerase sigma-24 subunit YP_008733915.1 2795886 R 1246995 CDS YP_008733916.1 556565491 17443242 complement(2796857..2797468) 1 NC_022657.1 COG1309 Transcriptional regulator; transcriptional regulator 2797468 17443242 AFR_12885 Actinoplanes friuliensis DSM 7358 transcriptional regulator YP_008733916.1 2796857 R 1246995 CDS YP_008733917.1 556565492 17443243 2797616..2798977 1 NC_022657.1 COG0277 FAD/FMN-containing dehydrogenases; FAD linked oxidase domain-containing protein 2798977 17443243 AFR_12890 Actinoplanes friuliensis DSM 7358 FAD linked oxidase domain-containing protein YP_008733917.1 2797616 D 1246995 CDS YP_008733918.1 556565493 17443244 complement(2798985..2799866) 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); short chain dehydrogenase 2799866 17443244 AFR_12895 Actinoplanes friuliensis DSM 7358 short chain dehydrogenase YP_008733918.1 2798985 R 1246995 CDS YP_008733919.1 556565494 17443245 2799934..2800767 1 NC_022657.1 COG1396 Predicted transcriptional regulators; XRE family transcriptional regulator 2800767 17443245 AFR_12900 Actinoplanes friuliensis DSM 7358 XRE family transcriptional regulator YP_008733919.1 2799934 D 1246995 CDS YP_008733920.1 556565495 17443246 2800879..2801439 1 NC_022657.1 integral membrane protein 2801439 17443246 AFR_12905 Actinoplanes friuliensis DSM 7358 integral membrane protein YP_008733920.1 2800879 D 1246995 CDS YP_008733921.1 556565496 17443247 2801441..2802862 1 NC_022657.1 COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes; pyridine nucleotide-disulfide oxidoreductase dimerization subunit 2802862 17443247 AFR_12910 Actinoplanes friuliensis DSM 7358 pyridine nucleotide-disulfide oxidoreductase dimerization subunit YP_008733921.1 2801441 D 1246995 CDS YP_008733922.1 556565497 17443248 2802891..2804435 1 NC_022657.1 COG0477 Permeases of the major facilitator superfamily; major facilitator superfamily permease 2804435 17443248 AFR_12915 Actinoplanes friuliensis DSM 7358 major facilitator superfamily permease YP_008733922.1 2802891 D 1246995 CDS YP_008733923.1 556565498 17443249 2804425..2804907 1 NC_022657.1 COG1846 Transcriptional regulators; Transcriptional regulator, MarR family protein 2804907 17443249 AFR_12920 Actinoplanes friuliensis DSM 7358 Transcriptional regulator, MarR family protein YP_008733923.1 2804425 D 1246995 CDS YP_008733924.1 556565499 17443250 complement(2804909..2805124) 1 NC_022657.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); alpha/beta hydrolase 2805124 17443250 AFR_12925 Actinoplanes friuliensis DSM 7358 alpha/beta hydrolase YP_008733924.1 2804909 R 1246995 CDS YP_008733925.1 556565500 17443251 complement(2805155..2805766) 1 NC_022657.1 COG1605 Chorismate mutase; chorismate mutase 2805766 17443251 AFR_12930 Actinoplanes friuliensis DSM 7358 chorismate mutase YP_008733925.1 2805155 R 1246995 CDS YP_008733926.1 556565501 17443252 2805989..2806543 1 NC_022657.1 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; RNA polymerase sigma factor SigL 2806543 17443252 AFR_12935 Actinoplanes friuliensis DSM 7358 RNA polymerase sigma factor SigL YP_008733926.1 2805989 D 1246995 CDS YP_008733927.1 556565502 17443253 complement(2806540..2807217) 1 NC_022657.1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; putative two-component system response regulator 2807217 17443253 AFR_12940 Actinoplanes friuliensis DSM 7358 putative two-component system response regulator YP_008733927.1 2806540 R 1246995 CDS YP_008733928.1 556565503 17443254 2807418..2808839 1 NC_022657.1 COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes; pyridine nucleotide-disulfide oxidoreductase dimerization subunit 2808839 17443254 AFR_12945 Actinoplanes friuliensis DSM 7358 pyridine nucleotide-disulfide oxidoreductase dimerization subunit YP_008733928.1 2807418 D 1246995 CDS YP_008733929.1 556565504 17443255 2808893..2809684 1 NC_022657.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); alpha/beta hydrolase 2809684 17443255 AFR_12950 Actinoplanes friuliensis DSM 7358 alpha/beta hydrolase YP_008733929.1 2808893 D 1246995 CDS YP_008733930.1 556565505 17443256 2809764..2810732 1 NC_022657.1 COG4977 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain; AraC family transcriptional regulator 2810732 17443256 AFR_12955 Actinoplanes friuliensis DSM 7358 AraC family transcriptional regulator YP_008733930.1 2809764 D 1246995 CDS YP_008733931.1 556565506 17443257 complement(2810761..2811627) 1 NC_022657.1 COG1396 Predicted transcriptional regulators; hypothetical protein 2811627 17443257 AFR_12960 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733931.1 2810761 R 1246995 CDS YP_008733932.1 556565507 17443258 2811804..2812889 1 NC_022657.1 COG0673 Predicted dehydrogenases and related proteins; oxidoreductase 2812889 17443258 AFR_12965 Actinoplanes friuliensis DSM 7358 oxidoreductase YP_008733932.1 2811804 D 1246995 CDS YP_008733933.1 556565508 17443259 complement(2812926..2813537) 1 NC_022657.1 COG1309 Transcriptional regulator; TetR family transcriptional regulator 2813537 17443259 AFR_12970 Actinoplanes friuliensis DSM 7358 TetR family transcriptional regulator YP_008733933.1 2812926 R 1246995 CDS YP_008733934.1 556565509 17443260 2813644..2814204 1 NC_022657.1 COG3247 Uncharacterized conserved protein; hypothetical protein 2814204 17443260 AFR_12975 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733934.1 2813644 D 1246995 CDS YP_008733935.1 556565510 17443261 complement(2814376..2814939) 1 NC_022657.1 COG1309 Transcriptional regulator; TetR family transcriptional regulator 2814939 17443261 AFR_12980 Actinoplanes friuliensis DSM 7358 TetR family transcriptional regulator YP_008733935.1 2814376 R 1246995 CDS YP_008733936.1 556565511 17443262 2815052..2815777 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); short-chain dehydrogenase/reductase SDR 2815777 17443262 AFR_12985 Actinoplanes friuliensis DSM 7358 short-chain dehydrogenase/reductase SDR YP_008733936.1 2815052 D 1246995 CDS YP_008733937.1 556565512 17443263 2815838..2816902 1 NC_022657.1 COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases); aldo/keto reductase 2816902 17443263 AFR_12990 Actinoplanes friuliensis DSM 7358 aldo/keto reductase YP_008733937.1 2815838 D 1246995 CDS YP_008733938.1 556565513 17443264 complement(2816924..2817553) 1 NC_022657.1 COG1309 Transcriptional regulator; TetR family transcriptional regulator 2817553 17443264 AFR_12995 Actinoplanes friuliensis DSM 7358 TetR family transcriptional regulator YP_008733938.1 2816924 R 1246995 CDS YP_008733939.1 556565514 17443265 2817685..2819031 1 NC_022657.1 COG0477 Permeases of the major facilitator superfamily; Major facilitator superfamily MFS_1 2819031 17443265 AFR_13000 Actinoplanes friuliensis DSM 7358 Major facilitator superfamily MFS_1 YP_008733939.1 2817685 D 1246995 CDS YP_008733940.1 556565515 17443266 2819028..2821787 1 NC_022657.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); beta-lactamase 2821787 17443266 AFR_13005 Actinoplanes friuliensis DSM 7358 beta-lactamase YP_008733940.1 2819028 D 1246995 CDS YP_008733941.1 556565516 17443267 2821903..2822424 1 NC_022657.1 COG1309 Transcriptional regulator; TetR family transcriptional regulator 2822424 17443267 AFR_13010 Actinoplanes friuliensis DSM 7358 TetR family transcriptional regulator YP_008733941.1 2821903 D 1246995 CDS YP_008733942.1 556565517 17443268 2822629..2823615 1 NC_022657.1 COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases; molecular chaperone GroES 2823615 17443268 AFR_13015 Actinoplanes friuliensis DSM 7358 molecular chaperone GroES YP_008733942.1 2822629 D 1246995 CDS YP_008733943.1 556565518 17443269 2823612..2824460 1 NC_022657.1 COG0702 Predicted nucleoside-diphosphate-sugar epimerases; NmrA family protein 2824460 17443269 AFR_13020 Actinoplanes friuliensis DSM 7358 NmrA family protein YP_008733943.1 2823612 D 1246995 CDS YP_008733944.1 556565519 17443270 complement(2824440..2824871) 1 NC_022657.1 COG1846 Transcriptional regulators; hypothetical protein 2824871 17443270 AFR_13025 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733944.1 2824440 R 1246995 CDS YP_008733945.1 556565520 17443271 2824952..2825767 1 NC_022657.1 COG0300 Short-chain dehydrogenases of various substrate specificities; dehydrogenase 2825767 17443271 AFR_13030 Actinoplanes friuliensis DSM 7358 dehydrogenase YP_008733945.1 2824952 D 1246995 CDS YP_008733946.1 556565521 17443272 2825843..2826142 1 NC_022657.1 hypothetical protein 2826142 17443272 AFR_13035 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733946.1 2825843 D 1246995 CDS YP_008733947.1 556565522 17443273 complement(2826161..2826754) 1 NC_022657.1 COG1309 Transcriptional regulator; TetR family transcriptional regulator 2826754 17443273 AFR_13040 Actinoplanes friuliensis DSM 7358 TetR family transcriptional regulator YP_008733947.1 2826161 R 1246995 CDS YP_008733948.1 556565523 17443274 2827072..2827890 1 NC_022657.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); 2-hydroxy-6-ketonona-2,4-dienedioic acid hydrolase 2827890 17443274 AFR_13045 Actinoplanes friuliensis DSM 7358 2-hydroxy-6-ketonona-2,4-dienedioic acid hydrolase YP_008733948.1 2827072 D 1246995 CDS YP_008733949.1 556565524 17443275 2827893..2828762 1 NC_022657.1 COG0346 Lactoylglutathione lyase and related lyases; bleomycin resistance protein 2828762 17443275 AFR_13050 Actinoplanes friuliensis DSM 7358 bleomycin resistance protein YP_008733949.1 2827893 D 1246995 CDS YP_008733950.1 556565525 17443276 2828759..2829508 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); 3-hydroxybutyrate dehydrogenase 2829508 17443276 AFR_13055 Actinoplanes friuliensis DSM 7358 3-hydroxybutyrate dehydrogenase YP_008733950.1 2828759 D 1246995 CDS YP_008733951.1 556565526 17443277 complement(2829524..2830141) 1 NC_022657.1 COG1309 Transcriptional regulator; TetR family transcriptional regulator 2830141 17443277 AFR_13060 Actinoplanes friuliensis DSM 7358 TetR family transcriptional regulator YP_008733951.1 2829524 R 1246995 CDS YP_008733952.1 556565527 17443278 complement(2830203..2831315) 1 NC_022657.1 hypothetical protein 2831315 17443278 AFR_13065 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733952.1 2830203 R 1246995 CDS YP_008733953.1 556565528 17443279 complement(2831357..2832352) 1 NC_022657.1 COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components; inner-membrane translocator 2832352 17443279 AFR_13070 Actinoplanes friuliensis DSM 7358 inner-membrane translocator YP_008733953.1 2831357 R 1246995 CDS YP_008733954.1 556565529 17443280 complement(2832382..2833869) 1 NC_022657.1 COG1129 ABC-type sugar transport system, ATPase component; ABC transporter 2833869 17443280 AFR_13075 Actinoplanes friuliensis DSM 7358 ABC transporter YP_008733954.1 2832382 R 1246995 CDS YP_008733955.1 556565530 17443281 complement(2833866..2836193) 1 NC_022657.1 COG0146 N-methylhydantoinase B/acetone carboxylase, alpha subunit; hydantoin utilization protein B 2836193 17443281 AFR_13080 Actinoplanes friuliensis DSM 7358 hydantoin utilization protein B YP_008733955.1 2833866 R 1246995 CDS YP_008733956.1 556565531 17443282 complement(2836205..2838283) 1 NC_022657.1 COG0145 N-methylhydantoinase A/acetone carboxylase, beta subunit; hydantoin utilization protein A 2838283 17443282 AFR_13085 Actinoplanes friuliensis DSM 7358 hydantoin utilization protein A YP_008733956.1 2836205 R 1246995 CDS YP_008733957.1 556565532 17443283 complement(2838326..2839954) 1 NC_022657.1 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases; hypothetical protein 2839954 17443283 AFR_13090 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733957.1 2838326 R 1246995 CDS YP_008733958.1 556565533 17443284 complement(2839951..2840697) 1 NC_022657.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); alpha/beta hydrolase fold protein 2840697 17443284 AFR_13095 Actinoplanes friuliensis DSM 7358 alpha/beta hydrolase fold protein YP_008733958.1 2839951 R 1246995 CDS YP_008733959.1 556565534 17443285 2840924..2841481 1 NC_022657.1 COG3247 Uncharacterized conserved protein; hypothetical protein 2841481 17443285 AFR_13100 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733959.1 2840924 D 1246995 CDS YP_008733960.1 556565535 17443286 2841604..2842719 1 NC_022657.1 COG2303 Choline dehydrogenase and related flavoproteins; glucose-methanol-choline oxidoreductase 2842719 17443286 AFR_13105 Actinoplanes friuliensis DSM 7358 glucose-methanol-choline oxidoreductase YP_008733960.1 2841604 D 1246995 CDS YP_008733961.1 556565536 17443287 complement(2842773..2844044) 1 NC_022657.1 COG0477 Permeases of the major facilitator superfamily; putative MFS permease 2844044 17443287 AFR_13110 Actinoplanes friuliensis DSM 7358 putative MFS permease YP_008733961.1 2842773 R 1246995 CDS YP_008733962.1 556565537 17443288 complement(2844175..2844810) 1 NC_022657.1 COG1309 Transcriptional regulator; hypothetical protein 2844810 17443288 AFR_13115 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733962.1 2844175 R 1246995 CDS YP_008733963.1 556565538 17443289 2844929..2847985 1 NC_022657.1 COG0383 Alpha-mannosidase; putative alpha-mannosidase 2847985 17443289 AFR_13120 Actinoplanes friuliensis DSM 7358 putative alpha-mannosidase YP_008733963.1 2844929 D 1246995 CDS YP_008733964.1 556565539 17443290 2848187..2848789 1 NC_022657.1 COG0693 Putative intracellular protease/amidase; ThiJ/PfpI domain protein 2848789 17443290 AFR_13125 Actinoplanes friuliensis DSM 7358 ThiJ/PfpI domain protein YP_008733964.1 2848187 D 1246995 CDS YP_008733965.1 556565540 17443291 complement(2848807..2849643) 1 NC_022657.1 COG1024 Enoyl-CoA hydratase/carnithine racemase; enoyl-CoA hydratase/isomerase 2849643 17443291 AFR_13130 Actinoplanes friuliensis DSM 7358 enoyl-CoA hydratase/isomerase YP_008733965.1 2848807 R 1246995 CDS YP_008733966.1 556565541 17443292 2849714..2850082 1 NC_022657.1 COG0789 Predicted transcriptional regulators; MerR family transcriptional regulator 2850082 17443292 AFR_13135 Actinoplanes friuliensis DSM 7358 MerR family transcriptional regulator YP_008733966.1 2849714 D 1246995 CDS YP_008733967.1 556565542 17443293 complement(2850122..2851105) 1 NC_022657.1 COG4977 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain; AraC family transcriptional regulator 2851105 17443293 AFR_13140 Actinoplanes friuliensis DSM 7358 AraC family transcriptional regulator YP_008733967.1 2850122 R 1246995 CDS YP_008733968.1 556565543 17443294 2851169..2851855 1 NC_022657.1 COG1335 Amidases related to nicotinamidase; isochorismatase hydrolase 2851855 17443294 AFR_13145 Actinoplanes friuliensis DSM 7358 isochorismatase hydrolase YP_008733968.1 2851169 D 1246995 CDS YP_008733969.1 556565544 17443295 2851924..2852601 1 NC_022657.1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; two component transcriptional regulator, winged helix family protein 2852601 17443295 AFR_13150 Actinoplanes friuliensis DSM 7358 two component transcriptional regulator, winged helix family protein YP_008733969.1 2851924 D 1246995 CDS YP_008733970.1 556565545 17443296 2852723..2854072 1 NC_022657.1 COG0642 Signal transduction histidine kinase; histidine kinase 2854072 17443296 AFR_13155 Actinoplanes friuliensis DSM 7358 histidine kinase YP_008733970.1 2852723 D 1246995 CDS YP_008733971.1 556565546 17443297 2854128..2855525 1 NC_022657.1 COG3463 Predicted membrane protein; hypothetical protein 2855525 17443297 AFR_13160 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733971.1 2854128 D 1246995 CDS YP_008733972.1 556565547 17443298 2855614..2856453 1 NC_022657.1 COG1396 Predicted transcriptional regulators; DNA-binding protein 2856453 17443298 AFR_13165 Actinoplanes friuliensis DSM 7358 DNA-binding protein YP_008733972.1 2855614 D 1246995 CDS YP_008733973.1 556565548 17443299 2856518..2857270 1 NC_022657.1 COG3967 Short-chain dehydrogenase involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein); putative oxidoreductase 2857270 17443299 AFR_13170 Actinoplanes friuliensis DSM 7358 putative oxidoreductase YP_008733973.1 2856518 D 1246995 CDS YP_008733974.1 556565549 17443300 2857430..2857822 1 NC_022657.1 COG5485 Predicted ester cyclase; hypothetical protein 2857822 17443300 AFR_13175 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733974.1 2857430 D 1246995 CDS YP_008733975.1 556565550 17443301 2857964..2858923 1 NC_022657.1 COG1609 Transcriptional regulators; putative LacI family transcriptional regulator 2858923 17443301 AFR_13180 Actinoplanes friuliensis DSM 7358 putative LacI family transcriptional regulator YP_008733975.1 2857964 D 1246995 CDS YP_008733976.1 556565551 17443302 2859036..2859980 1 NC_022657.1 COG0657 Esterase/lipase; esterase 2859980 17443302 AFR_13185 Actinoplanes friuliensis DSM 7358 esterase YP_008733976.1 2859036 D 1246995 CDS YP_008733977.1 556565552 17443303 2860015..2861385 1 NC_022657.1 COG1653 ABC-type sugar transport system, periplasmic component; extracellular solute-binding protein 2861385 17443303 AFR_13190 Actinoplanes friuliensis DSM 7358 extracellular solute-binding protein YP_008733977.1 2860015 D 1246995 CDS YP_008733978.1 556565553 17443304 2861390..2862298 1 NC_022657.1 COG1175 ABC-type sugar transport systems, permease components; binding-protein-dependent transport system inner membrane protein 2862298 17443304 AFR_13195 Actinoplanes friuliensis DSM 7358 binding-protein-dependent transport system inner membrane protein YP_008733978.1 2861390 D 1246995 CDS YP_008733979.1 556565554 17443305 2862295..2863119 1 NC_022657.1 COG0395 ABC-type sugar transport system, permease component; binding-protein-dependent transport system inner membrane protein 2863119 17443305 AFR_13200 Actinoplanes friuliensis DSM 7358 binding-protein-dependent transport system inner membrane protein YP_008733979.1 2862295 D 1246995 CDS YP_008733980.1 556565555 17443306 2863143..2864024 1 NC_022657.1 COG2755 Lysophospholipase L1 and related esterases; alpha/beta hydrolase 2864024 17443306 AFR_13205 Actinoplanes friuliensis DSM 7358 alpha/beta hydrolase YP_008733980.1 2863143 D 1246995 CDS YP_008733981.1 556565556 17443307 complement(2864031..2864504) 1 NC_022657.1 COG1846 Transcriptional regulators; regulatory protein MarR 2864504 17443307 AFR_13210 Actinoplanes friuliensis DSM 7358 regulatory protein MarR YP_008733981.1 2864031 R 1246995 CDS YP_008733982.1 556565557 17443308 2864614..2865546 1 NC_022657.1 COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases; alcohol dehydrogenase GroES domain-containing protein 2865546 17443308 AFR_13215 Actinoplanes friuliensis DSM 7358 alcohol dehydrogenase GroES domain-containing protein YP_008733982.1 2864614 D 1246995 CDS YP_008733983.1 556565558 17443309 2865627..2866304 1 NC_022657.1 COG1309 Transcriptional regulator; TetR family transcriptional regulator 2866304 17443309 AFR_13220 Actinoplanes friuliensis DSM 7358 TetR family transcriptional regulator YP_008733983.1 2865627 D 1246995 CDS YP_008733984.1 556565559 17443310 complement(2866301..2866933) 1 NC_022657.1 COG1309 Transcriptional regulator; TetR family transcriptional regulator 2866933 17443310 AFR_13225 Actinoplanes friuliensis DSM 7358 TetR family transcriptional regulator YP_008733984.1 2866301 R 1246995 CDS YP_008733985.1 556565560 17443311 2867039..2868163 1 NC_022657.1 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases; monooxygenase FAD-binding protein 2868163 17443311 AFR_13230 Actinoplanes friuliensis DSM 7358 monooxygenase FAD-binding protein YP_008733985.1 2867039 D 1246995 CDS YP_008733986.1 556565561 17443312 2868421..2870010 1 NC_022657.1 COG0840 Methyl-accepting chemotaxis protein; putative methyl-accepting chemotaxis protein 2870010 17443312 AFR_13235 Actinoplanes friuliensis DSM 7358 putative methyl-accepting chemotaxis protein YP_008733986.1 2868421 D 1246995 CDS YP_008733987.1 556565562 17443313 2870120..2873368 1 NC_022657.1 COG3209 Rhs family protein; RHS repeat-containing protein 2873368 17443313 AFR_13240 Actinoplanes friuliensis DSM 7358 RHS repeat-containing protein YP_008733987.1 2870120 D 1246995 CDS YP_008733988.1 556565563 17443314 complement(2873412..2875046) 1 NC_022657.1 hypothetical protein 2875046 17443314 AFR_13245 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733988.1 2873412 R 1246995 CDS YP_008733989.1 556565564 17443315 complement(2875163..2875648) 1 NC_022657.1 COG2085 Predicted dinucleotide-binding enzymes; NADP oxidoreductase, coenzyme F420-dependent 2875648 17443315 AFR_13250 Actinoplanes friuliensis DSM 7358 NADP oxidoreductase, coenzyme F420-dependent YP_008733989.1 2875163 R 1246995 CDS YP_008733990.1 556565565 17443316 complement(2875662..2876345) 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); short-chain dehydrogenase/reductase SDR 2876345 17443316 AFR_13255 Actinoplanes friuliensis DSM 7358 short-chain dehydrogenase/reductase SDR YP_008733990.1 2875662 R 1246995 CDS YP_008733991.1 556565566 17443317 2876422..2877033 1 NC_022657.1 COG1309 Transcriptional regulator; TetR family transcriptional regulator 2877033 17443317 AFR_13260 Actinoplanes friuliensis DSM 7358 TetR family transcriptional regulator YP_008733991.1 2876422 D 1246995 CDS YP_008733992.1 556565567 17443318 2877138..2878280 1 NC_022657.1 COG1835 Predicted acyltransferases; Putative peptidoglycan O-acetyltransferase yrhL 2878280 17443318 AFR_13265 Actinoplanes friuliensis DSM 7358 Putative peptidoglycan O-acetyltransferase yrhL YP_008733992.1 2877138 D 1246995 CDS YP_008733993.1 556565568 17443319 2878277..2878825 1 NC_022657.1 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; putative RNA polymerase ECF-subfamily sigma factor 2878825 17443319 AFR_13270 Actinoplanes friuliensis DSM 7358 putative RNA polymerase ECF-subfamily sigma factor YP_008733993.1 2878277 D 1246995 CDS YP_008733994.1 556565569 17443320 2878822..2879592 1 NC_022657.1 hypothetical protein 2879592 17443320 AFR_13275 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733994.1 2878822 D 1246995 CDS YP_008733995.1 556565570 17443321 complement(2879613..2880326) 1 NC_022657.1 COG5640 Secreted trypsin-like serine protease; peptidase S1 and S6 chymotrypsin/Hap 2880326 17443321 AFR_13280 Actinoplanes friuliensis DSM 7358 peptidase S1 and S6 chymotrypsin/Hap YP_008733995.1 2879613 R 1246995 CDS YP_008733996.1 556565571 17443322 complement(2880444..2881355) 1 NC_022657.1 COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases); aldo/keto reductase 2881355 17443322 AFR_13285 Actinoplanes friuliensis DSM 7358 aldo/keto reductase YP_008733996.1 2880444 R 1246995 CDS YP_008733997.1 556565572 17443323 2881443..2882141 1 NC_022657.1 COG1309 Transcriptional regulator; transcriptional regulator, TetR family protein 2882141 17443323 AFR_13290 Actinoplanes friuliensis DSM 7358 transcriptional regulator, TetR family protein YP_008733997.1 2881443 D 1246995 CDS YP_008733998.1 556565573 17443324 complement(2882183..2884369) 1 NC_022657.1 hypothetical protein 2884369 17443324 AFR_13295 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008733998.1 2882183 R 1246995 CDS YP_008733999.1 556565574 17443325 2884513..2885493 1 NC_022657.1 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases; putative luciferase-like monooxygenase 2885493 17443325 AFR_13300 Actinoplanes friuliensis DSM 7358 putative luciferase-like monooxygenase YP_008733999.1 2884513 D 1246995 CDS YP_008734000.1 556565575 17443326 2885490..2885810 1 NC_022657.1 COG2314 Predicted membrane protein; DnaJ-like subfamily C member 22 protein 2885810 17443326 AFR_13305 Actinoplanes friuliensis DSM 7358 DnaJ-like subfamily C member 22 protein YP_008734000.1 2885490 D 1246995 CDS YP_008734001.1 556565576 17443327 2885994..2887670 1 NC_022657.1 hypothetical protein 2887670 17443327 AFR_13310 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734001.1 2885994 D 1246995 CDS YP_008734002.1 556565577 17443328 complement(2887678..2888193) 1 NC_022657.1 hypothetical protein 2888193 17443328 AFR_13315 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734002.1 2887678 R 1246995 CDS YP_008734003.1 556565578 17443329 2888384..2889016 1 NC_022657.1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; putative two-component system response regulator 2889016 17443329 AFR_13320 Actinoplanes friuliensis DSM 7358 putative two-component system response regulator YP_008734003.1 2888384 D 1246995 CDS YP_008734004.1 556565579 17443330 2889016..2890803 1 NC_022657.1 COG0642 Signal transduction histidine kinase; putative two-component system sensor kinase 2890803 17443330 AFR_13325 Actinoplanes friuliensis DSM 7358 putative two-component system sensor kinase YP_008734004.1 2889016 D 1246995 CDS YP_008734005.1 556565580 17443331 2890864..2891979 1 NC_022657.1 hypothetical protein 2891979 17443331 AFR_13330 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734005.1 2890864 D 1246995 CDS YP_008734006.1 556565581 17443332 2892092..2893255 1 NC_022657.1 COG0577 ABC-type antimicrobial peptide transport system, permease component; putative permease 2893255 17443332 AFR_13335 Actinoplanes friuliensis DSM 7358 putative permease YP_008734006.1 2892092 D 1246995 CDS YP_008734007.1 556565582 17443333 complement(2893298..2894041) 1 NC_022657.1 COG3967 Short-chain dehydrogenase involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein); short-chain dehydrogenase/reductase SDR 2894041 17443333 AFR_13340 Actinoplanes friuliensis DSM 7358 short-chain dehydrogenase/reductase SDR YP_008734007.1 2893298 R 1246995 CDS YP_008734008.1 556565583 17443334 2894145..2894960 1 NC_022657.1 COG1396 Predicted transcriptional regulators; DNA-binding protein 2894960 17443334 AFR_13345 Actinoplanes friuliensis DSM 7358 DNA-binding protein YP_008734008.1 2894145 D 1246995 CDS YP_008734009.1 556565584 17443335 complement(2894979..2896649) 1 NC_022657.1 hypothetical protein 2896649 17443335 AFR_13350 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734009.1 2894979 R 1246995 CDS YP_008734010.1 556565585 17443336 2896795..2898450 1 NC_022657.1 COG0366 Glycosidases; alpha amylase 2898450 17443336 AFR_13355 Actinoplanes friuliensis DSM 7358 alpha amylase YP_008734010.1 2896795 D 1246995 CDS YP_008734011.1 556565586 17443337 complement(2898478..2899095) 1 NC_022657.1 hypothetical protein 2899095 17443337 AFR_13360 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734011.1 2898478 R 1246995 CDS YP_008734012.1 556565587 17443338 complement(2899143..2899961) 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); short-chain dehydrogenase/reductase SDR 2899961 17443338 AFR_13365 Actinoplanes friuliensis DSM 7358 short-chain dehydrogenase/reductase SDR YP_008734012.1 2899143 R 1246995 CDS YP_008734013.1 556565588 17443339 2900067..2900948 1 NC_022657.1 COG0583 Transcriptional regulator; LysR family transcriptional regulator 2900948 17443339 AFR_13370 Actinoplanes friuliensis DSM 7358 LysR family transcriptional regulator YP_008734013.1 2900067 D 1246995 CDS YP_008734014.1 556565589 17443340 2900999..2901604 1 NC_022657.1 COG1309 Transcriptional regulator; TetR family transcriptional regulator 2901604 17443340 AFR_13375 Actinoplanes friuliensis DSM 7358 TetR family transcriptional regulator YP_008734014.1 2900999 D 1246995 CDS YP_008734015.1 556565590 17443341 2901650..2902408 1 NC_022657.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); alpha/beta hydrolase 2902408 17443341 AFR_13380 Actinoplanes friuliensis DSM 7358 alpha/beta hydrolase YP_008734015.1 2901650 D 1246995 CDS YP_008734016.1 556565591 17443342 complement(2902423..2903868) 1 NC_022657.1 COG0477 Permeases of the major facilitator superfamily; transport protein 2903868 17443342 AFR_13385 Actinoplanes friuliensis DSM 7358 transport protein YP_008734016.1 2902423 R 1246995 CDS YP_008734017.1 556565592 17443343 2903956..2904171 1 NC_022657.1 hypothetical protein 2904171 17443343 AFR_13390 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734017.1 2903956 D 1246995 CDS YP_008734018.1 556565593 17443344 2904267..2904635 1 NC_022657.1 COG1725 Predicted transcriptional regulators; GntR family transcriptional regulator 2904635 17443344 AFR_13395 Actinoplanes friuliensis DSM 7358 GntR family transcriptional regulator YP_008734018.1 2904267 D 1246995 CDS YP_008734019.1 556565594 17443345 2904659..2905597 1 NC_022657.1 hypothetical protein 2905597 17443345 AFR_13400 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734019.1 2904659 D 1246995 CDS YP_008734020.1 556565595 17443346 complement(2905588..2905773) 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); short-chain dehydrogenase/reductase SDR 2905773 17443346 AFR_13405 Actinoplanes friuliensis DSM 7358 short-chain dehydrogenase/reductase SDR YP_008734020.1 2905588 R 1246995 CDS YP_008734021.1 556565596 17443347 2905938..2906357 1 NC_022657.1 COG0673 Predicted dehydrogenases and related proteins; oxidoreductase domain-containing protein 2906357 17443347 AFR_13410 Actinoplanes friuliensis DSM 7358 oxidoreductase domain-containing protein YP_008734021.1 2905938 D 1246995 CDS YP_008734022.1 556565597 17443348 complement(2906347..2906841) 1 NC_022657.1 hypothetical protein 2906841 17443348 AFR_13415 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734022.1 2906347 R 1246995 CDS YP_008734023.1 556565598 17443349 complement(2906828..2908456) 1 NC_022657.1 COG1960 Acyl-CoA dehydrogenases; acyl-CoA dehydrogenase domain-containing protein 2908456 17443349 AFR_13420 Actinoplanes friuliensis DSM 7358 acyl-CoA dehydrogenase domain-containing protein YP_008734023.1 2906828 R 1246995 CDS YP_008734024.1 556565599 17443350 2908937..2909410 1 NC_022657.1 hypothetical protein 2909410 17443350 AFR_13425 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734024.1 2908937 D 1246995 CDS YP_008734025.1 556565600 17443351 complement(2909453..2909998) 1 NC_022657.1 COG2203 FOG: GAF domain; hypothetical protein 2909998 17443351 AFR_13430 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734025.1 2909453 R 1246995 CDS YP_008734026.1 556565601 17443352 complement(2910016..2910591) 1 NC_022657.1 COG2229 Predicted GTPase; hypothetical protein 2910591 17443352 AFR_13435 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734026.1 2910016 R 1246995 CDS YP_008734027.1 556565602 17443353 complement(2910569..2910946) 1 NC_022657.1 multi-component regulatory system-3 2910946 17443353 AFR_13440 Actinoplanes friuliensis DSM 7358 multi-component regulatory system-3 YP_008734027.1 2910569 R 1246995 CDS YP_008734028.1 556565603 17443354 complement(2910943..2911377) 1 NC_022657.1 Roadblock/LC7 family protein 2911377 17443354 AFR_13445 Actinoplanes friuliensis DSM 7358 Roadblock/LC7 family protein YP_008734028.1 2910943 R 1246995 CDS YP_008734029.1 556565604 17443355 complement(2911409..2912839) 1 NC_022657.1 COG0642 Signal transduction histidine kinase; ATP-binding region ATPase domain-containing protein 2912839 17443355 AFR_13450 Actinoplanes friuliensis DSM 7358 ATP-binding region ATPase domain-containing protein YP_008734029.1 2911409 R 1246995 CDS YP_008734030.1 556565605 17443356 complement(2913115..2913798) 1 NC_022657.1 COG2186 Transcriptional regulators; GntR family transcriptional regulator 2913798 17443356 AFR_13455 Actinoplanes friuliensis DSM 7358 GntR family transcriptional regulator YP_008734030.1 2913115 R 1246995 CDS YP_008734031.1 556565606 17443357 complement(2913808..2914998) 1 NC_022657.1 COG2807 Cyanate permease; transporter 2914998 17443357 AFR_13460 Actinoplanes friuliensis DSM 7358 transporter YP_008734031.1 2913808 R 1246995 CDS YP_008734032.1 556565607 17443358 2915127..2917436 1 NC_022657.1 COG0466 ATP-dependent Lon protease, bacterial type; ATP-dependent protease La 2917436 17443358 AFR_13465 Actinoplanes friuliensis DSM 7358 ATP-dependent protease La YP_008734032.1 2915127 D 1246995 CDS YP_008734033.1 556565608 17443359 complement(2917516..2918025) 1 NC_022657.1 hypothetical protein 2918025 17443359 AFR_13470 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734033.1 2917516 R 1246995 CDS YP_008734034.1 556565609 17443360 2918121..2918315 1 NC_022657.1 COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases); aldo/keto reductase 2918315 17443360 AFR_13475 Actinoplanes friuliensis DSM 7358 aldo/keto reductase YP_008734034.1 2918121 D 1246995 CDS YP_008734035.1 556565610 17443361 2918335..2918517 1 NC_022657.1 COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases); putative oxidoreductase 2918517 17443361 AFR_13480 Actinoplanes friuliensis DSM 7358 putative oxidoreductase YP_008734035.1 2918335 D 1246995 CDS YP_008734036.1 556565611 17443362 complement(2918529..2919311) 1 NC_022657.1 COG0300 Short-chain dehydrogenases of various substrate specificities; oxidoreductase 2919311 17443362 AFR_13485 Actinoplanes friuliensis DSM 7358 oxidoreductase YP_008734036.1 2918529 R 1246995 CDS YP_008734037.1 556565612 17443363 2919436..2920038 1 NC_022657.1 COG1309 Transcriptional regulator; putative transcriptional regulatory protein (TetR-family) 2920038 17443363 AFR_13490 Actinoplanes friuliensis DSM 7358 putative transcriptional regulatory protein (TetR-family) YP_008734037.1 2919436 D 1246995 CDS YP_008734038.1 556565613 17443364 complement(2920047..2920949) 1 NC_022657.1 COG0583 Transcriptional regulator; LysR family transcriptional regulator 2920949 17443364 AFR_13495 Actinoplanes friuliensis DSM 7358 LysR family transcriptional regulator YP_008734038.1 2920047 R 1246995 CDS YP_008734039.1 556565614 17443365 2921058..2921987 1 NC_022657.1 COG0451 Nucleoside-diphosphate-sugar epimerases; 3-beta hydroxysteroid dehydrogenase/isomerase 2921987 17443365 AFR_13500 Actinoplanes friuliensis DSM 7358 3-beta hydroxysteroid dehydrogenase/isomerase YP_008734039.1 2921058 D 1246995 CDS YP_008734040.1 556565615 17443366 2922059..2923252 1 NC_022657.1 COG2814 Arabinose efflux permease; major facilitator family transporter 2923252 17443366 AFR_13505 Actinoplanes friuliensis DSM 7358 major facilitator family transporter YP_008734040.1 2922059 D 1246995 CDS YP_008734041.1 556565616 17443367 2923373..2923675 1 NC_022657.1 COG2343 Uncharacterized protein conserved in bacteria; hypothetical protein 2923675 17443367 AFR_13510 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734041.1 2923373 D 1246995 CDS YP_008734042.1 556565617 17443368 complement(2923689..2924471) 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); short-chain dehydrogenase/reductase SDR 2924471 17443368 AFR_13515 Actinoplanes friuliensis DSM 7358 short-chain dehydrogenase/reductase SDR YP_008734042.1 2923689 R 1246995 CDS YP_008734043.1 556565618 17443369 2924559..2925413 1 NC_022657.1 COG1396 Predicted transcriptional regulators; DNA-binding protein 2925413 17443369 AFR_13520 Actinoplanes friuliensis DSM 7358 DNA-binding protein YP_008734043.1 2924559 D 1246995 CDS YP_008734044.1 556565619 17443370 2925544..2926116 1 NC_022657.1 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; RNA polymerase sigma-70 factor, ECF subfamily protein 2926116 17443370 AFR_13525 Actinoplanes friuliensis DSM 7358 RNA polymerase sigma-70 factor, ECF subfamily protein YP_008734044.1 2925544 D 1246995 CDS YP_008734045.1 556565620 17443371 2926113..2927258 1 NC_022657.1 hypothetical protein 2927258 17443371 AFR_13530 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734045.1 2926113 D 1246995 CDS YP_008734046.1 556565621 17443372 complement(2927354..2928181) 1 NC_022657.1 COG1396 Predicted transcriptional regulators; helix-turn-helix domain-containing protein 2928181 17443372 AFR_13535 Actinoplanes friuliensis DSM 7358 helix-turn-helix domain-containing protein YP_008734046.1 2927354 R 1246995 CDS YP_008734047.1 556565622 17443373 2928269..2928985 1 NC_022657.1 COG4221 Short-chain alcohol dehydrogenase of unknown specificity; short-chain dehydrogenase 2928985 17443373 AFR_13540 Actinoplanes friuliensis DSM 7358 short-chain dehydrogenase YP_008734047.1 2928269 D 1246995 CDS YP_008734048.1 556565623 17443374 2929024..2929632 1 NC_022657.1 hypothetical protein 2929632 17443374 AFR_13545 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734048.1 2929024 D 1246995 CDS YP_008734049.1 556565624 17443375 complement(2929668..2930429) 1 NC_022657.1 COG1077 Actin-like ATPase involved in cell morphogenesis; cell shape determining protein mreb/mrl 2930429 17443375 AFR_13550 Actinoplanes friuliensis DSM 7358 cell shape determining protein mreb/mrl YP_008734049.1 2929668 R 1246995 CDS YP_008734050.1 556565625 17443376 complement(2930465..2931217) 1 NC_022657.1 COG0517 FOG: CBS domain; cbs domain-containing membrane protein 2931217 17443376 AFR_13555 Actinoplanes friuliensis DSM 7358 cbs domain-containing membrane protein YP_008734050.1 2930465 R 1246995 CDS YP_008734051.1 556565626 17443377 2931495..2932739 1 NC_022657.1 COG2508 Regulator of polyketide synthase expression; transcriptional regulator CdaR 2932739 17443377 AFR_13560 Actinoplanes friuliensis DSM 7358 transcriptional regulator CdaR YP_008734051.1 2931495 D 1246995 CDS YP_008734052.1 556565627 17443378 complement(2932747..2933040) 1 NC_022657.1 hypothetical protein 2933040 17443378 AFR_13565 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734052.1 2932747 R 1246995 CDS YP_008734053.1 556565628 17443379 complement(2933100..2933897) 1 NC_022657.1 COG0517 FOG: CBS domain; cbs domain-containing membrane protein 2933897 17443379 AFR_13570 Actinoplanes friuliensis DSM 7358 cbs domain-containing membrane protein YP_008734053.1 2933100 R 1246995 CDS YP_008734054.1 556565629 17443380 2934325..2935233 1 NC_022657.1 COG0665 Glycine/D-amino acid oxidases (deaminating); D-amino-acid dehydrogenase 2935233 17443380 AFR_13575 Actinoplanes friuliensis DSM 7358 D-amino-acid dehydrogenase YP_008734054.1 2934325 D 1246995 CDS YP_008734055.1 556565630 17443381 2935274..2935573 1 NC_022657.1 hypothetical protein 2935573 17443381 AFR_13580 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734055.1 2935274 D 1246995 CDS YP_008734056.1 556565631 17443382 complement(2935623..2936189) 1 NC_022657.1 COG1309 Transcriptional regulator; TetR family transcriptional regulator 2936189 17443382 AFR_13585 Actinoplanes friuliensis DSM 7358 TetR family transcriptional regulator YP_008734056.1 2935623 R 1246995 CDS YP_008734057.1 556565632 17443383 2936292..2937368 1 NC_022657.1 COG3268 Uncharacterized conserved protein; hypothetical protein 2937368 17443383 AFR_13590 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734057.1 2936292 D 1246995 CDS YP_008734058.1 556565633 17443384 complement(2937372..2937947) 1 NC_022657.1 COG1309 Transcriptional regulator; TetR family transcriptional regulator 2937947 17443384 AFR_13595 Actinoplanes friuliensis DSM 7358 TetR family transcriptional regulator YP_008734058.1 2937372 R 1246995 CDS YP_008734059.1 556565634 17443385 2938036..2938647 1 NC_022657.1 COG0702 Predicted nucleoside-diphosphate-sugar epimerases; nucleoside-diphosphate-sugar epimerase 2938647 17443385 AFR_13600 Actinoplanes friuliensis DSM 7358 nucleoside-diphosphate-sugar epimerase YP_008734059.1 2938036 D 1246995 CDS YP_008734060.1 556565635 17443386 2938644..2939519 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); short-chain dehydrogenase/reductase SDR 2939519 17443386 AFR_13605 Actinoplanes friuliensis DSM 7358 short-chain dehydrogenase/reductase SDR YP_008734060.1 2938644 D 1246995 CDS YP_008734061.1 556565636 17443387 complement(2939596..2941854) 1 NC_022657.1 COG0525 Valyl-tRNA synthetase; hypothetical protein 2941854 17443387 AFR_13610 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734061.1 2939596 R 1246995 CDS YP_008734062.1 556565637 17443388 complement(2942296..2943030) 1 NC_022657.1 hypothetical protein 2943030 17443388 AFR_13615 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734062.1 2942296 R 1246995 CDS YP_008734063.1 556565638 17443389 complement(2943099..2943470) 1 NC_022657.1 COG4334 Uncharacterized protein conserved in bacteria; hypothetical protein 2943470 17443389 AFR_13620 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734063.1 2943099 R 1246995 CDS YP_008734064.1 556565639 17443390 2943700..2944587 1 NC_022657.1 COG1396 Predicted transcriptional regulators; helix-turn-helix domain-containing protein 2944587 17443390 AFR_13625 Actinoplanes friuliensis DSM 7358 helix-turn-helix domain-containing protein YP_008734064.1 2943700 D 1246995 CDS YP_008734065.1 556565640 17443391 2944623..2945459 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); short chain dehydrogenase 2945459 17443391 AFR_13630 Actinoplanes friuliensis DSM 7358 short chain dehydrogenase YP_008734065.1 2944623 D 1246995 CDS YP_008734066.1 556565641 17443392 complement(2945466..2946356) 1 NC_022657.1 COG1396 Predicted transcriptional regulators; helix-turn-helix domain-containing protein 2946356 17443392 AFR_13635 Actinoplanes friuliensis DSM 7358 helix-turn-helix domain-containing protein YP_008734066.1 2945466 R 1246995 CDS YP_008734067.1 556565642 17443393 2946448..2948049 1 NC_022657.1 COG0025 NhaP-type Na+/H+ and K+/H+ antiporters; Na+/H+ antiporter 2948049 17443393 AFR_13640 Actinoplanes friuliensis DSM 7358 Na+/H+ antiporter YP_008734067.1 2946448 D 1246995 CDS YP_008734068.1 556565643 17443394 complement(2948055..2948264) 1 NC_022657.1 hypothetical protein 2948264 17443394 AFR_13645 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734068.1 2948055 R 1246995 CDS YP_008734069.1 556565644 17443395 complement(2948342..2949022) 1 NC_022657.1 COG2085 Predicted dinucleotide-binding enzymes; putative F420-dependent NADP oxidoreductase 2949022 17443395 AFR_13650 Actinoplanes friuliensis DSM 7358 putative F420-dependent NADP oxidoreductase YP_008734069.1 2948342 R 1246995 CDS YP_008734070.1 556565645 17443396 complement(2949019..2950071) 1 NC_022657.1 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases; putative luciferase-like monooxygenase 2950071 17443396 AFR_13655 Actinoplanes friuliensis DSM 7358 putative luciferase-like monooxygenase YP_008734070.1 2949019 R 1246995 CDS YP_008734071.1 556565646 17443397 complement(2950159..2950560) 1 NC_022657.1 hypothetical protein 2950560 17443397 AFR_13660 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734071.1 2950159 R 1246995 CDS YP_008734072.1 556565647 17443398 2950664..2951260 1 NC_022657.1 COG1309 Transcriptional regulator; TetR family transcriptional regulator 2951260 17443398 AFR_13665 Actinoplanes friuliensis DSM 7358 TetR family transcriptional regulator YP_008734072.1 2950664 D 1246995 CDS YP_008734073.1 556565648 17443399 complement(2951284..2952753) 1 NC_022657.1 hypothetical protein 2952753 17443399 AFR_13670 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734073.1 2951284 R 1246995 CDS YP_008734074.1 556565649 17443400 2952897..2953439 1 NC_022657.1 COG5637 Predicted integral membrane protein; putative 17.2 kDa protein in melC2-rnhH intergenic region 2953439 17443400 AFR_13675 Actinoplanes friuliensis DSM 7358 putative 17.2 kDa protein in melC2-rnhH intergenic region YP_008734074.1 2952897 D 1246995 CDS YP_008734075.1 556565650 17443401 2953436..2954611 1 NC_022657.1 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases; alcohol dehydrogenase 2954611 17443401 AFR_13680 Actinoplanes friuliensis DSM 7358 alcohol dehydrogenase YP_008734075.1 2953436 D 1246995 CDS YP_008734076.1 556565651 17443402 2954622..2955641 1 NC_022657.1 COG2207 AraC-type DNA-binding domain-containing proteins; putative AraC-family transcriptional regulator 2955641 17443402 AFR_13685 Actinoplanes friuliensis DSM 7358 putative AraC-family transcriptional regulator YP_008734076.1 2954622 D 1246995 CDS YP_008734077.1 556565652 17443403 2955822..2956115 1 NC_022657.1 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); anti-anti-sigma factor 2956115 17443403 AFR_13690 Actinoplanes friuliensis DSM 7358 anti-anti-sigma factor YP_008734077.1 2955822 D 1246995 CDS YP_008734078.1 556565653 17443404 2956196..2956972 1 NC_022657.1 COG3173 Predicted aminoglycoside phosphotransferase; aminoglycoside phosphotransferase 2956972 17443404 AFR_13695 Actinoplanes friuliensis DSM 7358 aminoglycoside phosphotransferase YP_008734078.1 2956196 D 1246995 CDS YP_008734079.1 556565654 17443405 2957041..2958324 1 NC_022657.1 COG0534 Na+-driven multidrug efflux pump; MATE efflux family protein 2958324 17443405 AFR_13700 Actinoplanes friuliensis DSM 7358 MATE efflux family protein YP_008734079.1 2957041 D 1246995 CDS YP_008734080.1 556565655 17443406 2958402..2959106 1 NC_022657.1 COG1309 Transcriptional regulator; TetR family transcriptional regulator 2959106 17443406 AFR_13705 Actinoplanes friuliensis DSM 7358 TetR family transcriptional regulator YP_008734080.1 2958402 D 1246995 CDS YP_008734081.1 556565656 17443407 2959244..2959936 1 NC_022657.1 hypothetical protein 2959936 17443407 AFR_13710 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734081.1 2959244 D 1246995 CDS YP_008734082.1 556565657 17443408 complement(2959914..2960153) 1 NC_022657.1 hypothetical protein 2960153 17443408 AFR_13715 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734082.1 2959914 R 1246995 CDS YP_008734083.1 556565658 17443409 2960381..2961157 1 NC_022657.1 peptidase S1 and S6 chymotrypsin/Hap 2961157 17443409 AFR_13720 Actinoplanes friuliensis DSM 7358 peptidase S1 and S6 chymotrypsin/Hap YP_008734083.1 2960381 D 1246995 CDS YP_008734084.1 556565659 17443410 2961350..2962141 1 NC_022657.1 COG2755 Lysophospholipase L1 and related esterases; G-D-S-L family lipolytic protein 2962141 17443410 AFR_13725 Actinoplanes friuliensis DSM 7358 G-D-S-L family lipolytic protein YP_008734084.1 2961350 D 1246995 CDS YP_008734085.1 556565660 17443411 2962141..2962635 1 NC_022657.1 hypothetical protein 2962635 17443411 AFR_13730 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734085.1 2962141 D 1246995 CDS YP_008734086.1 556565661 17443412 complement(2962688..2963347) 1 NC_022657.1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; putative two-component system response regulator 2963347 17443412 AFR_13735 Actinoplanes friuliensis DSM 7358 putative two-component system response regulator YP_008734086.1 2962688 R 1246995 CDS YP_008734087.1 556565662 17443413 complement(2963361..2964554) 1 NC_022657.1 COG4585 Signal transduction histidine kinase; putative two-component system sensor kinase 2964554 17443413 AFR_13740 Actinoplanes friuliensis DSM 7358 putative two-component system sensor kinase YP_008734087.1 2963361 R 1246995 CDS YP_008734088.1 556565663 17443414 2964838..2965995 1 NC_022657.1 COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway); 2-keto-4-pentenoate hydratase 2965995 17443414 AFR_13745 Actinoplanes friuliensis DSM 7358 2-keto-4-pentenoate hydratase YP_008734088.1 2964838 D 1246995 CDS YP_008734089.1 556565664 17443415 2966143..2967741 1 NC_022657.1 COG0025 NhaP-type Na+/H+ and K+/H+ antiporters; Na+/H+ antiporter 2967741 17443415 AFR_13750 Actinoplanes friuliensis DSM 7358 Na+/H+ antiporter YP_008734089.1 2966143 D 1246995 CDS YP_008734090.1 556565665 17443416 complement(2967859..2968782) 1 NC_022657.1 COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases; NADPH:quinone reductase-related Zn-dependent oxidoreductase 2968782 17443416 AFR_13755 Actinoplanes friuliensis DSM 7358 NADPH:quinone reductase-related Zn-dependent oxidoreductase YP_008734090.1 2967859 R 1246995 CDS YP_008734091.1 556565666 17443417 complement(2968888..2969277) 1 NC_022657.1 COG0789 Predicted transcriptional regulators; MerR family transcriptional regulator 2969277 17443417 AFR_13760 Actinoplanes friuliensis DSM 7358 MerR family transcriptional regulator YP_008734091.1 2968888 R 1246995 CDS YP_008734092.1 556565667 17443418 2969711..2971327 1 NC_022657.1 COG1215 Glycosyltransferases, probably involved in cell wall biogenesis; cellulose synthase 2971327 17443418 AFR_13765 Actinoplanes friuliensis DSM 7358 cellulose synthase YP_008734092.1 2969711 D 1246995 CDS YP_008734093.1 556565668 17443419 2971378..2972148 1 NC_022657.1 COG1566 Multidrug resistance efflux pump; hypothetical protein 2972148 17443419 AFR_13770 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734093.1 2971378 D 1246995 CDS YP_008734094.1 556565669 17443420 2972166..2974268 1 NC_022657.1 COG5498 Predicted glycosyl hydrolase; endo-1,3(4)-beta-glucanase 2974268 17443420 AFR_13775 Actinoplanes friuliensis DSM 7358 endo-1,3(4)-beta-glucanase YP_008734094.1 2972166 D 1246995 CDS YP_008734095.1 556565670 17443421 2974338..2974793 1 NC_022657.1 hypothetical protein 2974793 17443421 AFR_13780 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734095.1 2974338 D 1246995 CDS YP_008734096.1 556565671 17443422 2974854..2975663 1 NC_022657.1 COG0266 Formamidopyrimidine-DNA glycosylase; DNA-(apurinic or apyrimidinic site) lyase 2975663 17443422 AFR_13785 Actinoplanes friuliensis DSM 7358 DNA-(apurinic or apyrimidinic site) lyase YP_008734096.1 2974854 D 1246995 CDS YP_008734097.1 556565672 17443423 2975739..2976164 1 NC_022657.1 hypothetical protein 2976164 17443423 AFR_13790 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734097.1 2975739 D 1246995 CDS YP_008734098.1 556565673 17443424 2976254..2977837 1 NC_022657.1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; SARP family transcriptional regulator 2977837 17443424 AFR_13795 Actinoplanes friuliensis DSM 7358 SARP family transcriptional regulator YP_008734098.1 2976254 D 1246995 CDS YP_008734099.1 556565674 17443425 2977944..2979773 1 NC_022657.1 COG3934 Endo-beta-mannanase; hypothetical protein 2979773 17443425 AFR_13800 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734099.1 2977944 D 1246995 CDS YP_008734100.1 556565675 17443426 complement(2979825..2980127) 1 NC_022657.1 hypothetical protein 2980127 17443426 AFR_13805 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734100.1 2979825 R 1246995 CDS YP_008734101.1 556565676 17443427 2980698..2982344 1 NC_022657.1 COG2060 K+-transporting ATPase, A chain; potassium-transporting ATPase subunit A 2982344 17443427 AFR_13810 Actinoplanes friuliensis DSM 7358 potassium-transporting ATPase subunit A YP_008734101.1 2980698 D 1246995 CDS YP_008734102.1 556565677 17443428 2982341..2984500 1 NC_022657.1 COG2216 High-affinity K+ transport system, ATPase chain B; potassium-transporting ATPase subunit B 2984500 17443428 AFR_13815 Actinoplanes friuliensis DSM 7358 potassium-transporting ATPase subunit B YP_008734102.1 2982341 D 1246995 CDS YP_008734103.1 556565678 17443429 2984506..2985369 1 NC_022657.1 COG2156 K+-transporting ATPase, c chain; K transporting ATPase KdpC subunit 2985369 17443429 AFR_13820 Actinoplanes friuliensis DSM 7358 K transporting ATPase KdpC subunit YP_008734103.1 2984506 D 1246995 CDS YP_008734104.1 556565679 17443430 2985370..2987844 1 NC_022657.1 COG2205 Osmosensitive K+ channel histidine kinase; putative two-component system sensor kinase for high-affinity potassium transport system 2987844 17443430 AFR_13825 Actinoplanes friuliensis DSM 7358 putative two-component system sensor kinase for high-affinity potassium transport system YP_008734104.1 2985370 D 1246995 CDS YP_008734105.1 556565680 17443431 2987888..2988487 1 NC_022657.1 hypothetical protein 2988487 17443431 AFR_13830 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734105.1 2987888 D 1246995 CDS YP_008734106.1 556565681 17443432 complement(2988468..2989484) 1 NC_022657.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); alpha/beta hydrolase fold protein 2989484 17443432 AFR_13835 Actinoplanes friuliensis DSM 7358 alpha/beta hydrolase fold protein YP_008734106.1 2988468 R 1246995 CDS YP_008734107.1 556565682 17443433 complement(2989487..2990698) 1 NC_022657.1 COG0477 Permeases of the major facilitator superfamily; putative major facilitator superfamily transporter 2990698 17443433 AFR_13840 Actinoplanes friuliensis DSM 7358 putative major facilitator superfamily transporter YP_008734107.1 2989487 R 1246995 CDS YP_008734108.1 556565683 17443434 2990838..2991353 1 NC_022657.1 COG1309 Transcriptional regulator; regulatory protein TetR 2991353 17443434 AFR_13845 Actinoplanes friuliensis DSM 7358 regulatory protein TetR YP_008734108.1 2990838 D 1246995 CDS YP_008734109.1 556565684 17443435 complement(2991443..2992141) 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); short chain oxidoreductase 2992141 17443435 AFR_13850 Actinoplanes friuliensis DSM 7358 short chain oxidoreductase YP_008734109.1 2991443 R 1246995 CDS YP_008734110.1 556565685 17443436 2992237..2993055 1 NC_022657.1 COG1396 Predicted transcriptional regulators; HTH-type transcriptional regulator 2993055 17443436 AFR_13855 Actinoplanes friuliensis DSM 7358 HTH-type transcriptional regulator YP_008734110.1 2992237 D 1246995 CDS YP_008734111.1 556565686 17443437 2993180..2993485 1 NC_022657.1 hypothetical protein 2993485 17443437 AFR_13860 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734111.1 2993180 D 1246995 CDS YP_008734112.1 556565687 17443438 2994546..2995337 1 NC_022657.1 hypothetical protein 2995337 17443438 AFR_13865 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734112.1 2994546 D 1246995 CDS YP_008734113.1 556565688 17443439 2995383..2996126 1 NC_022657.1 COG0500 SAM-dependent methyltransferases; hypothetical protein 2996126 17443439 AFR_13870 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734113.1 2995383 D 1246995 CDS YP_008734114.1 556565689 17443440 2996766..2997641 1 NC_022657.1 COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases; hypothetical protein 2997641 17443440 AFR_13875 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734114.1 2996766 D 1246995 CDS YP_008734115.1 556565690 17443441 2997765..2998838 1 NC_022657.1 COG0665 Glycine/D-amino acid oxidases (deaminating); glycine oxidase ThiO 2998838 17443441 AFR_13880 Actinoplanes friuliensis DSM 7358 glycine oxidase ThiO YP_008734115.1 2997765 D 1246995 CDS YP_008734116.1 556565691 17443442 2998880..3002026 1 NC_022657.1 COG0464 ATPases of the AAA+ class; hypothetical protein 3002026 17443442 AFR_13885 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734116.1 2998880 D 1246995 CDS YP_008734117.1 556565692 17443443 3002117..3002905 1 NC_022657.1 COG0500 SAM-dependent methyltransferases; RNA methylase-like protein 3002905 17443443 AFR_13890 Actinoplanes friuliensis DSM 7358 RNA methylase-like protein YP_008734117.1 3002117 D 1246995 CDS YP_008734118.1 556565693 17443444 3003458..3003673 1 NC_022657.1 hypothetical protein 3003673 17443444 AFR_13895 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734118.1 3003458 D 1246995 CDS YP_008734119.1 556565694 17443445 complement(3003674..3004234) 1 NC_022657.1 COG1309 Transcriptional regulator; TetR family transcriptional regulator 3004234 17443445 AFR_13900 Actinoplanes friuliensis DSM 7358 TetR family transcriptional regulator YP_008734119.1 3003674 R 1246995 CDS YP_008734120.1 556565695 17443446 complement(3004261..3004872) 1 NC_022657.1 hypothetical protein 3004872 17443446 AFR_13905 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734120.1 3004261 R 1246995 CDS YP_008734121.1 556565696 17443447 3004950..3005834 1 NC_022657.1 COG3001 Fructosamine-3-kinase; aminoglycoside phosphotransferase 3005834 17443447 AFR_13910 Actinoplanes friuliensis DSM 7358 aminoglycoside phosphotransferase YP_008734121.1 3004950 D 1246995 CDS YP_008734122.1 556565697 17443448 complement(3005860..3006897) 1 NC_022657.1 hypothetical protein 3006897 17443448 AFR_13915 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734122.1 3005860 R 1246995 CDS YP_008734123.1 556565698 17443449 complement(3006988..3009252) 1 NC_022657.1 COG2409 Predicted drug exporters of the RND superfamily; hypothetical protein 3009252 17443449 AFR_13920 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734123.1 3006988 R 1246995 CDS YP_008734124.1 556565699 17443450 3009391..3012792 1 NC_022657.1 COG2133 Glucose/sorbosone dehydrogenases; hypothetical protein 3012792 17443450 AFR_13925 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734124.1 3009391 D 1246995 CDS YP_008734125.1 556565700 17443451 3012814..3013326 1 NC_022657.1 hypothetical protein 3013326 17443451 AFR_13930 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734125.1 3012814 D 1246995 CDS YP_008734126.1 556565701 17443452 complement(3013328..3014446) 1 NC_022657.1 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases; putative FAD-dependent monooxygenase 3014446 17443452 AFR_13935 Actinoplanes friuliensis DSM 7358 putative FAD-dependent monooxygenase YP_008734126.1 3013328 R 1246995 CDS YP_008734127.1 556565702 17443453 complement(3014536..3016128) 1 NC_022657.1 COG2199 FOG: GGDEF domain; diguanylate cyclase 3016128 17443453 AFR_13940 Actinoplanes friuliensis DSM 7358 diguanylate cyclase YP_008734127.1 3014536 R 1246995 CDS YP_008734128.1 556565703 17443454 3016363..3017784 1 NC_022657.1 COG1404 Subtilisin-like serine proteases; peptidase S8 and S53 subtilisin kexin sedolisin 3017784 17443454 AFR_13945 Actinoplanes friuliensis DSM 7358 peptidase S8 and S53 subtilisin kexin sedolisin YP_008734128.1 3016363 D 1246995 CDS YP_008734129.1 556565704 17443455 complement(3017822..3018436) 1 NC_022657.1 COG1309 Transcriptional regulator; regulatory protein TetR 3018436 17443455 AFR_13950 Actinoplanes friuliensis DSM 7358 regulatory protein TetR YP_008734129.1 3017822 R 1246995 CDS YP_008734130.1 556565705 17443456 3018545..3018970 1 NC_022657.1 hypothetical protein 3018970 17443456 AFR_13955 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734130.1 3018545 D 1246995 CDS YP_008734131.1 556565706 17443457 complement(3018974..3020053) 1 NC_022657.1 COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases; alcohol dehydrogenase zinc-binding domain-containing protein 3020053 17443457 AFR_13960 Actinoplanes friuliensis DSM 7358 alcohol dehydrogenase zinc-binding domain-containing protein YP_008734131.1 3018974 R 1246995 CDS YP_008734132.1 556565707 17443458 3020123..3020848 1 NC_022657.1 COG1396 Predicted transcriptional regulators; hypothetical protein 3020848 17443458 AFR_13965 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734132.1 3020123 D 1246995 CDS YP_008734133.1 556565708 17443459 complement(3020852..3021643) 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); putative short-chain dehydrogenase 3021643 17443459 AFR_13970 Actinoplanes friuliensis DSM 7358 putative short-chain dehydrogenase YP_008734133.1 3020852 R 1246995 CDS YP_008734134.1 556565709 17443460 complement(3021752..3022153) 1 NC_022657.1 COG2340 Uncharacterized protein with SCP/PR1 domains; hypothetical protein 3022153 17443460 AFR_13975 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734134.1 3021752 R 1246995 CDS YP_008734135.1 556565710 17443461 3022393..3023985 1 NC_022657.1 COG0747 ABC-type dipeptide transport system, periplasmic component; family 5 extracellular solute-binding protein 3023985 17443461 AFR_13980 Actinoplanes friuliensis DSM 7358 family 5 extracellular solute-binding protein YP_008734135.1 3022393 D 1246995 CDS YP_008734136.1 556565711 17443462 3024036..3024992 1 NC_022657.1 COG0601 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components; binding-protein-dependent transport systems inner membrane component 3024992 17443462 AFR_13985 Actinoplanes friuliensis DSM 7358 binding-protein-dependent transport systems inner membrane component YP_008734136.1 3024036 D 1246995 CDS YP_008734137.1 556565712 17443463 3024985..3025857 1 NC_022657.1 COG1173 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components; binding-protein-dependent transport system inner membrane protein 3025857 17443463 AFR_13990 Actinoplanes friuliensis DSM 7358 binding-protein-dependent transport system inner membrane protein YP_008734137.1 3024985 D 1246995 CDS YP_008734138.1 556565713 17443464 3025854..3026813 1 NC_022657.1 COG0444 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component; oligopeptide/dipeptide ABC transporter ATPase 3026813 17443464 AFR_13995 Actinoplanes friuliensis DSM 7358 oligopeptide/dipeptide ABC transporter ATPase YP_008734138.1 3025854 D 1246995 CDS YP_008734139.1 556565714 17443465 3026810..3027472 1 NC_022657.1 COG4608 ABC-type oligopeptide transport system, ATPase component; ABC transporter-like protein 3027472 17443465 AFR_14000 Actinoplanes friuliensis DSM 7358 ABC transporter-like protein YP_008734139.1 3026810 D 1246995 CDS YP_008734140.1 556565715 17443466 3027520..3028383 1 NC_022657.1 hypothetical protein 3028383 17443466 AFR_14005 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734140.1 3027520 D 1246995 CDS YP_008734141.1 556565716 17443467 complement(3028399..3028956) 1 NC_022657.1 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; ECF subfamily RNA polymerase sigma-24 factor 3028956 17443467 AFR_14010 Actinoplanes friuliensis DSM 7358 ECF subfamily RNA polymerase sigma-24 factor YP_008734141.1 3028399 R 1246995 CDS YP_008734142.1 556565717 17443468 complement(3029018..3029500) 1 NC_022657.1 hypothetical protein 3029500 17443468 AFR_14015 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734142.1 3029018 R 1246995 CDS YP_008734143.1 556565718 17443469 complement(3029674..3031152) 1 NC_022657.1 COG3182 Uncharacterized iron-regulated membrane protein; integral membrane protein 3031152 17443469 AFR_14020 Actinoplanes friuliensis DSM 7358 integral membrane protein YP_008734143.1 3029674 R 1246995 CDS YP_008734144.1 556565719 17443470 complement(3031208..3031798) 1 NC_022657.1 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; ECF subfamily RNA polymerase sigma-24 factor 3031798 17443470 AFR_14025 Actinoplanes friuliensis DSM 7358 ECF subfamily RNA polymerase sigma-24 factor YP_008734144.1 3031208 R 1246995 CDS YP_008734145.1 556565720 17443471 3031950..3033944 1 NC_022657.1 COG3336 Predicted membrane protein; putative cytochrome c oxidase caa3 assembly factor 3033944 17443471 AFR_14030 Actinoplanes friuliensis DSM 7358 putative cytochrome c oxidase caa3 assembly factor YP_008734145.1 3031950 D 1246995 CDS YP_008734146.1 556565721 17443472 3033969..3034571 1 NC_022657.1 hypothetical protein 3034571 17443472 AFR_14035 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734146.1 3033969 D 1246995 CDS YP_008734147.1 556565722 17443473 3034522..3035073 1 NC_022657.1 COG2847 Uncharacterized protein conserved in bacteria; hypothetical protein 3035073 17443473 AFR_14040 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734147.1 3034522 D 1246995 CDS YP_008734148.1 556565723 17443474 3035091..3036251 1 NC_022657.1 COG2837 Predicted iron-dependent peroxidase; putative peroxidase 3036251 17443474 AFR_14045 Actinoplanes friuliensis DSM 7358 putative peroxidase YP_008734148.1 3035091 D 1246995 CDS YP_008734149.1 556565724 17443475 3036248..3036844 1 NC_022657.1 COG2372 Uncharacterized protein, homolog of Cu resistance protein CopC; putative copper resistance protein CopC 3036844 17443475 AFR_14050 Actinoplanes friuliensis DSM 7358 putative copper resistance protein CopC YP_008734149.1 3036248 D 1246995 CDS YP_008734150.1 556565725 17443476 complement(3036908..3038482) 1 NC_022657.1 COG0477 Permeases of the major facilitator superfamily; EmrB/QacA subfamily drug resistance transporter 3038482 17443476 AFR_14055 Actinoplanes friuliensis DSM 7358 EmrB/QacA subfamily drug resistance transporter YP_008734150.1 3036908 R 1246995 CDS YP_008734151.1 556565726 17443477 complement(3038686..3040509) 1 NC_022657.1 COG3851 Signal transduction histidine kinase, glucose-6-phosphate specific; two-component system histidine kinase 3040509 17443477 AFR_14060 Actinoplanes friuliensis DSM 7358 two-component system histidine kinase YP_008734151.1 3038686 R 1246995 CDS YP_008734152.1 556565727 17443478 complement(3040506..3041174) 1 NC_022657.1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; two-component system response regulator 3041174 17443478 AFR_14065 Actinoplanes friuliensis DSM 7358 two-component system response regulator YP_008734152.1 3040506 R 1246995 CDS YP_008734153.1 556565728 17443479 3041349..3041720 1 NC_022657.1 hypothetical protein 3041720 17443479 AFR_14070 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734153.1 3041349 D 1246995 CDS YP_008734154.1 556565729 17443480 3041806..3043119 1 NC_022657.1 hypothetical protein 3043119 17443480 AFR_14075 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734154.1 3041806 D 1246995 CDS YP_008734155.1 556565730 17443481 complement(3044096..3044335) 1 NC_022657.1 COG2085 Predicted dinucleotide-binding enzymes; hypothetical protein 3044335 17443481 AFR_14090 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734155.1 3044096 R 1246995 CDS YP_008734156.1 556565731 17443482 complement(3046632..3047834) 1 NC_022657.1 COG2203 FOG: GAF domain; putative signaling protein 3047834 17443482 AFR_14105 Actinoplanes friuliensis DSM 7358 putative signaling protein YP_008734156.1 3046632 R 1246995 CDS YP_008734157.1 556565732 17443483 complement(3047993..3048550) 1 NC_022657.1 Protein containing ChW-repeats 3048550 17443483 AFR_14110 Actinoplanes friuliensis DSM 7358 Protein containing ChW-repeats YP_008734157.1 3047993 R 1246995 CDS YP_008734158.1 556565733 17443484 3048906..3049508 1 NC_022657.1 hypothetical protein 3049508 17443484 AFR_14115 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734158.1 3048906 D 1246995 CDS YP_008734159.1 556565734 17443485 3049597..3050928 1 NC_022657.1 COG0015 Adenylosuccinate lyase; adenylosuccinate lyase 3050928 17443485 AFR_14120 Actinoplanes friuliensis DSM 7358 adenylosuccinate lyase YP_008734159.1 3049597 D 1246995 CDS YP_008734160.1 556565735 17443486 complement(3050947..3051249) 1 NC_022657.1 hypothetical protein 3051249 17443486 AFR_14125 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734160.1 3050947 R 1246995 CDS YP_008734161.1 556565736 17443487 3051352..3051636 1 NC_022657.1 hypothetical protein 3051636 17443487 AFR_14130 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734161.1 3051352 D 1246995 CDS YP_008734162.1 556565737 17443488 complement(3051653..3052858) 1 NC_022657.1 COG2208 Serine phosphatase RsbU, regulator of sigma subunit; Protein icfG 3052858 17443488 AFR_14135 Actinoplanes friuliensis DSM 7358 Protein icfG YP_008734162.1 3051653 R 1246995 CDS YP_008734163.1 556565738 17443489 3053056..3053289 1 NC_022657.1 hypothetical protein 3053289 17443489 AFR_14140 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734163.1 3053056 D 1246995 CDS YP_008734164.1 556565739 17443490 3053452..3053766 1 NC_022657.1 hypothetical protein 3053766 17443490 AFR_14145 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734164.1 3053452 D 1246995 CDS YP_008734165.1 556565740 17443491 complement(3053771..3054427) 1 NC_022657.1 COG1802 Transcriptional regulators; GntR family transcriptional regulator 3054427 17443491 AFR_14150 Actinoplanes friuliensis DSM 7358 GntR family transcriptional regulator YP_008734165.1 3053771 R 1246995 CDS YP_008734166.1 556565741 17443492 3054551..3055246 1 NC_022657.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); hypothetical protein 3055246 17443492 AFR_14155 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734166.1 3054551 D 1246995 CDS YP_008734167.1 556565742 17443493 3055317..3055994 1 NC_022657.1 COG2860 Predicted membrane protein; hypothetical protein 3055994 17443493 AFR_14160 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734167.1 3055317 D 1246995 CDS YP_008734168.1 556565743 17443494 complement(3056003..3056434) 1 NC_022657.1 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; acetyltransferase 3056434 17443494 AFR_14165 Actinoplanes friuliensis DSM 7358 acetyltransferase YP_008734168.1 3056003 R 1246995 CDS YP_008734169.1 556565744 17443495 3056545..3057372 1 NC_022657.1 COG0789 Predicted transcriptional regulators; MerR family transcriptional regulator 3057372 17443495 AFR_14170 Actinoplanes friuliensis DSM 7358 MerR family transcriptional regulator YP_008734169.1 3056545 D 1246995 CDS YP_008734170.1 556565745 17443496 3057536..3058735 1 NC_022657.1 COG2262 GTPases; GTP-binding protein HflX 3058735 17443496 AFR_14175 Actinoplanes friuliensis DSM 7358 GTP-binding protein HflX YP_008734170.1 3057536 D 1246995 CDS YP_008734171.1 556565746 17443497 3058756..3060507 1 NC_022657.1 COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]; pyruvate dehydrogenase 3060507 17443497 AFR_14180 Actinoplanes friuliensis DSM 7358 pyruvate dehydrogenase YP_008734171.1 3058756 D 1246995 CDS YP_008734172.1 556565747 17443498 complement(3060523..3062799) 1 NC_022657.1 COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain; diguanylate cyclase/phosphodiesterase 3062799 17443498 AFR_14185 Actinoplanes friuliensis DSM 7358 diguanylate cyclase/phosphodiesterase YP_008734172.1 3060523 R 1246995 CDS YP_008734173.1 556565748 17443499 complement(3062861..3063508) 1 NC_022657.1 COG3576 Predicted flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase; pyridoxamine 5'-phosphate oxidase-related protein 3063508 17443499 AFR_14190 Actinoplanes friuliensis DSM 7358 pyridoxamine 5'-phosphate oxidase-related protein YP_008734173.1 3062861 R 1246995 CDS YP_008734174.1 556565749 17443500 complement(3063584..3064165) 1 NC_022657.1 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; GCN5-related N-acetyltransferase 3064165 17443500 AFR_14195 Actinoplanes friuliensis DSM 7358 GCN5-related N-acetyltransferase YP_008734174.1 3063584 R 1246995 CDS YP_008734175.1 556565750 17443501 complement(3064322..3064699) 1 NC_022657.1 COG0251 Putative translation initiation inhibitor, yjgF family; putative endoribonuclease L-PSP 3064699 17443501 AFR_14200 Actinoplanes friuliensis DSM 7358 putative endoribonuclease L-PSP YP_008734175.1 3064322 R 1246995 CDS YP_008734176.1 556565751 17443502 complement(3064768..3065646) 1 NC_022657.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); alpha/beta hydrolase 3065646 17443502 AFR_14205 Actinoplanes friuliensis DSM 7358 alpha/beta hydrolase YP_008734176.1 3064768 R 1246995 CDS YP_008734177.1 556565752 17443503 3065724..3066377 1 NC_022657.1 COG1309 Transcriptional regulator; putative TetR-family transcriptional regulator 3066377 17443503 AFR_14210 Actinoplanes friuliensis DSM 7358 putative TetR-family transcriptional regulator YP_008734177.1 3065724 D 1246995 CDS YP_008734178.1 556565753 17443504 complement(3066378..3067547) 1 NC_022657.1 COG1520 FOG: WD40-like repeat; hypothetical protein 3067547 17443504 AFR_14215 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734178.1 3066378 R 1246995 CDS YP_008734179.1 556565754 17443505 3067700..3068725 1 NC_022657.1 COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases; alcohol dehydrogenase zinc-binding domain-containing protein 3068725 17443505 AFR_14220 Actinoplanes friuliensis DSM 7358 alcohol dehydrogenase zinc-binding domain-containing protein YP_008734179.1 3067700 D 1246995 CDS YP_008734180.1 556565755 17443506 complement(3068709..3069170) 1 NC_022657.1 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; N-acetyltransferase GCN5 3069170 17443506 AFR_14225 Actinoplanes friuliensis DSM 7358 N-acetyltransferase GCN5 YP_008734180.1 3068709 R 1246995 CDS YP_008734181.1 556565756 17443507 3069279..3069554 1 NC_022657.1 hypothetical protein 3069554 17443507 AFR_14230 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734181.1 3069279 D 1246995 CDS YP_008734182.1 556565757 17443508 3069535..3070446 1 NC_022657.1 COG2207 AraC-type DNA-binding domain-containing proteins; AraC family transcriptional regulator 3070446 17443508 AFR_14235 Actinoplanes friuliensis DSM 7358 AraC family transcriptional regulator YP_008734182.1 3069535 D 1246995 CDS YP_008734183.1 556565758 17443509 complement(3070666..3070923) 1 NC_022657.1 hypothetical protein 3070923 17443509 AFR_14240 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734183.1 3070666 R 1246995 CDS YP_008734184.1 556565759 17443510 complement(3071053..3072408) 1 NC_022657.1 COG0675 Transposase and inactivated derivatives; hypothetical protein 3072408 17443510 AFR_14245 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734184.1 3071053 R 1246995 CDS YP_008734185.1 556565760 17443511 3072600..3072929 1 NC_022657.1 hypothetical protein 3072929 17443511 AFR_14250 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734185.1 3072600 D 1246995 CDS YP_008734186.1 556565761 17443512 complement(3072942..3073811) 1 NC_022657.1 COG1216 Predicted glycosyltransferases; glycosyl transferase family protein 3073811 17443512 AFR_14255 Actinoplanes friuliensis DSM 7358 glycosyl transferase family protein YP_008734186.1 3072942 R 1246995 CDS YP_008734187.1 556565762 17443513 3073964..3074353 1 NC_022657.1 COG3832 Uncharacterized conserved protein; hypothetical protein 3074353 17443513 AFR_14260 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734187.1 3073964 D 1246995 CDS YP_008734188.1 556565763 17443514 complement(3074559..3074819) 1 NC_022657.1 hypothetical protein 3074819 17443514 AFR_14265 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734188.1 3074559 R 1246995 CDS YP_008734189.1 556565764 17443515 complement(3074859..3076616) 1 NC_022657.1 COG0843 Heme/copper-type cytochrome/quinol oxidases, subunit 1; putative cytochrome c oxidase subunit I 3076616 17443515 AFR_14270 Actinoplanes friuliensis DSM 7358 putative cytochrome c oxidase subunit I YP_008734189.1 3074859 R 1246995 CDS YP_008734190.1 556565765 17443516 3076758..3078860 1 NC_022657.1 COG2409 Predicted drug exporters of the RND superfamily; hypothetical protein 3078860 17443516 AFR_14275 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734190.1 3076758 D 1246995 CDS YP_008734191.1 556565766 17443517 3078902..3079954 1 NC_022657.1 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases; alcohol dehydrogenase GroES domain-containing protein 3079954 17443517 AFR_14280 Actinoplanes friuliensis DSM 7358 alcohol dehydrogenase GroES domain-containing protein YP_008734191.1 3078902 D 1246995 CDS YP_008734192.1 556565767 17443518 3080024..3081091 1 NC_022657.1 COG0701 Predicted permeases; putative permease 3081091 17443518 AFR_14285 Actinoplanes friuliensis DSM 7358 putative permease YP_008734192.1 3080024 D 1246995 CDS YP_008734193.1 556565768 17443519 3081193..3082530 1 NC_022657.1 COG3004 Na+/H+ antiporter; putative sodium/proton antiporter 3082530 17443519 AFR_14290 Actinoplanes friuliensis DSM 7358 putative sodium/proton antiporter YP_008734193.1 3081193 D 1246995 CDS YP_008734194.1 556565769 17443520 complement(3082521..3084110) 1 NC_022657.1 COG3559 Putative exporter of polyketide antibiotics; putative exporter of polyketide antibiotics-like protein 3084110 17443520 AFR_14295 Actinoplanes friuliensis DSM 7358 putative exporter of polyketide antibiotics-like protein YP_008734194.1 3082521 R 1246995 CDS YP_008734195.1 556565770 17443521 complement(3084107..3085006) 1 NC_022657.1 COG1131 ABC-type multidrug transport system, ATPase component; ABC transporter 3085006 17443521 AFR_14300 Actinoplanes friuliensis DSM 7358 ABC transporter YP_008734195.1 3084107 R 1246995 CDS YP_008734196.1 556565771 17443522 3085202..3086356 1 NC_022657.1 COG1680 Beta-lactamase class C and other penicillin binding proteins; beta-lactamase 3086356 17443522 AFR_14305 Actinoplanes friuliensis DSM 7358 beta-lactamase YP_008734196.1 3085202 D 1246995 CDS YP_008734197.1 556565772 17443523 3086529..3087431 1 NC_022657.1 hypothetical protein 3087431 17443523 AFR_14310 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734197.1 3086529 D 1246995 CDS YP_008734198.1 556565773 17443524 3087702..3088637 1 NC_022657.1 COG1878 Predicted metal-dependent hydrolase; hypothetical protein 3088637 17443524 AFR_14315 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734198.1 3087702 D 1246995 CDS YP_008734199.1 556565774 17443525 complement(3088648..3090129) 1 NC_022657.1 COG1070 Sugar (pentulose and hexulose) kinases; putative FGGY-family carbohydrate kinase 3090129 17443525 AFR_14320 Actinoplanes friuliensis DSM 7358 putative FGGY-family carbohydrate kinase YP_008734199.1 3088648 R 1246995 CDS YP_008734200.1 556565775 17443526 3090334..3095286 1 NC_022657.1 COG3537 Putative alpha-1,2-mannosidase; alpha-1,2-mannosidase family protein 3095286 17443526 AFR_14325 Actinoplanes friuliensis DSM 7358 alpha-1,2-mannosidase family protein YP_008734200.1 3090334 D 1246995 CDS YP_008734201.1 556565776 17443527 3095468..3096736 1 NC_022657.1 ECF subfamily RNA polymerase sigma-24 subunit 3096736 17443527 AFR_14330 Actinoplanes friuliensis DSM 7358 ECF subfamily RNA polymerase sigma-24 subunit YP_008734201.1 3095468 D 1246995 CDS YP_008734202.1 556565777 17443528 complement(3096741..3098666) 1 NC_022657.1 COG1154 Deoxyxylulose-5-phosphate synthase; 1-deoxy-D-xylulose-5-phosphate synthase 3098666 17443528 AFR_14335 Actinoplanes friuliensis DSM 7358 1-deoxy-D-xylulose-5-phosphate synthase YP_008734202.1 3096741 R 1246995 CDS YP_008734203.1 556565778 17443529 complement(3098717..3099253) 1 NC_022657.1 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins; N-acetyltransferase GCN5 3099253 17443529 AFR_14340 Actinoplanes friuliensis DSM 7358 N-acetyltransferase GCN5 YP_008734203.1 3098717 R 1246995 CDS YP_008734204.1 556565779 17443530 3099329..3100549 1 NC_022657.1 COG0477 Permeases of the major facilitator superfamily; drug resistance transporter 3100549 17443530 AFR_14345 Actinoplanes friuliensis DSM 7358 drug resistance transporter YP_008734204.1 3099329 D 1246995 CDS YP_008734205.1 556565780 17443531 3100718..3101953 1 NC_022657.1 COG1653 ABC-type sugar transport system, periplasmic component; family 1 extracellular solute-binding protein 3101953 17443531 AFR_14350 Actinoplanes friuliensis DSM 7358 family 1 extracellular solute-binding protein YP_008734205.1 3100718 D 1246995 CDS YP_008734206.1 556565781 17443532 3101950..3102822 1 NC_022657.1 COG1175 ABC-type sugar transport systems, permease components; carbohydrate ABC transporter membrane protein 3102822 17443532 AFR_14355 Actinoplanes friuliensis DSM 7358 carbohydrate ABC transporter membrane protein YP_008734206.1 3101950 D 1246995 CDS YP_008734207.1 556565782 17443533 3102822..3103667 1 NC_022657.1 COG0395 ABC-type sugar transport system, permease component; binding-protein-dependent transport systems inner membrane component 3103667 17443533 AFR_14360 Actinoplanes friuliensis DSM 7358 binding-protein-dependent transport systems inner membrane component YP_008734207.1 3102822 D 1246995 CDS YP_008734208.1 556565783 17443534 complement(3103675..3104070) 1 NC_022657.1 hypothetical protein 3104070 17443534 AFR_14365 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734208.1 3103675 R 1246995 CDS YP_008734209.1 556565784 17443535 complement(3104124..3104591) 1 NC_022657.1 COG3558 Uncharacterized protein conserved in bacteria; hypothetical protein 3104591 17443535 AFR_14370 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734209.1 3104124 R 1246995 CDS YP_008734210.1 556565785 17443536 complement(3104588..3105124) 1 NC_022657.1 COG2128 Uncharacterized conserved protein; hypothetical protein 3105124 17443536 AFR_14375 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734210.1 3104588 R 1246995 CDS YP_008734211.1 556565786 17443537 3105219..3105794 1 NC_022657.1 hypothetical protein 3105794 17443537 AFR_14380 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734211.1 3105219 D 1246995 CDS YP_008734212.1 556565787 17443538 complement(3105781..3106359) 1 NC_022657.1 COG1309 Transcriptional regulator; TetR family transcriptional regulator 3106359 17443538 AFR_14385 Actinoplanes friuliensis DSM 7358 TetR family transcriptional regulator YP_008734212.1 3105781 R 1246995 CDS YP_008734213.1 556565788 17443539 3106451..3107332 1 NC_022657.1 COG0451 Nucleoside-diphosphate-sugar epimerases; hypothetical protein 3107332 17443539 AFR_14390 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734213.1 3106451 D 1246995 CDS YP_008734214.1 556565789 17443540 complement(3107379..3107984) 1 NC_022657.1 COG1309 Transcriptional regulator; TetR family transcriptional regulator 3107984 17443540 AFR_14395 Actinoplanes friuliensis DSM 7358 TetR family transcriptional regulator YP_008734214.1 3107379 R 1246995 CDS YP_008734215.1 556565790 17443541 3108077..3108793 1 NC_022657.1 COG3967 Short-chain dehydrogenase involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein); short-chain dehydrogenase/reductase SDR 3108793 17443541 AFR_14400 Actinoplanes friuliensis DSM 7358 short-chain dehydrogenase/reductase SDR YP_008734215.1 3108077 D 1246995 CDS YP_008734216.1 556565791 17443542 3108924..3109400 1 NC_022657.1 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; RNA polymerase sigma-E factor 3109400 17443542 AFR_14405 Actinoplanes friuliensis DSM 7358 RNA polymerase sigma-E factor YP_008734216.1 3108924 D 1246995 CDS YP_008734217.1 556565792 17443543 3109397..3110122 1 NC_022657.1 hypothetical protein 3110122 17443543 AFR_14410 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734217.1 3109397 D 1246995 CDS YP_008734218.1 556565793 17443544 complement(3110130..3110993) 1 NC_022657.1 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases; hypothetical protein 3110993 17443544 AFR_14415 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734218.1 3110130 R 1246995 CDS YP_008734219.1 556565794 17443545 complement(3111003..3111278) 1 NC_022657.1 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs; 2Fe-2S cluster binding protein 3111278 17443545 AFR_14420 Actinoplanes friuliensis DSM 7358 2Fe-2S cluster binding protein YP_008734219.1 3111003 R 1246995 CDS YP_008734220.1 556565795 17443546 complement(3111272..3112087) 1 NC_022657.1 COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs; putative carbon monoxide dehydrogenase medium subunit 3112087 17443546 AFR_14425 Actinoplanes friuliensis DSM 7358 putative carbon monoxide dehydrogenase medium subunit YP_008734220.1 3111272 R 1246995 CDS YP_008734221.1 556565796 17443547 3112297..3113619 1 NC_022657.1 COG2723 Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase; beta-galactosidase 3113619 17443547 AFR_14430 Actinoplanes friuliensis DSM 7358 beta-galactosidase YP_008734221.1 3112297 D 1246995 CDS YP_008734222.1 556565797 17443548 3113616..3114830 1 NC_022657.1 COG0477 Permeases of the major facilitator superfamily; major facilitator superfamily protein 3114830 17443548 AFR_14435 Actinoplanes friuliensis DSM 7358 major facilitator superfamily protein YP_008734222.1 3113616 D 1246995 CDS YP_008734223.1 556565798 17443549 complement(3114836..3115282) 1 NC_022657.1 hypothetical protein 3115282 17443549 AFR_14440 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734223.1 3114836 R 1246995 CDS YP_008734224.1 556565799 17443550 complement(3115541..3116371) 1 NC_022657.1 COG2510 Predicted membrane protein; hypothetical protein 3116371 17443550 AFR_14445 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734224.1 3115541 R 1246995 CDS YP_008734225.1 556565800 17443551 complement(3116406..3118424) 1 NC_022657.1 hypothetical protein 3118424 17443551 AFR_14450 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734225.1 3116406 R 1246995 CDS YP_008734226.1 556565801 17443552 3118763..3119524 1 NC_022657.1 arabinofuranosidase 3119524 17443552 AFR_14455 Actinoplanes friuliensis DSM 7358 arabinofuranosidase YP_008734226.1 3118763 D 1246995 CDS YP_008734227.1 556565802 17443553 3119535..3120539 1 NC_022657.1 COG0583 Transcriptional regulator; LysR-family transcriptional regulator 3120539 17443553 AFR_14460 Actinoplanes friuliensis DSM 7358 LysR-family transcriptional regulator YP_008734227.1 3119535 D 1246995 CDS YP_008734228.1 556565803 17443554 complement(3120547..3120951) 1 NC_022657.1 hypothetical protein 3120951 17443554 AFR_14465 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734228.1 3120547 R 1246995 CDS YP_008734229.1 556565804 17443555 complement(3120948..3121910) 1 NC_022657.1 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; RNA polymerase factor sigma-70 3121910 17443555 AFR_14470 Actinoplanes friuliensis DSM 7358 RNA polymerase factor sigma-70 YP_008734229.1 3120948 R 1246995 CDS YP_008734230.1 556565805 17443556 complement(3122053..3123177) 1 NC_022657.1 peptide chain release factor subunit 1 3123177 17443556 AFR_14475 Actinoplanes friuliensis DSM 7358 peptide chain release factor subunit 1 YP_008734230.1 3122053 R 1246995 CDS YP_008734231.1 556565806 17443557 3123330..3123614 1 NC_022657.1 hypothetical protein 3123614 17443557 AFR_14480 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734231.1 3123330 D 1246995 CDS YP_008734232.1 556565807 17443558 complement(3123875..3124459) 1 NC_022657.1 hypothetical protein 3124459 17443558 AFR_14485 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734232.1 3123875 R 1246995 CDS YP_008734233.1 556565808 17443559 3124723..3125430 1 NC_022657.1 COG2203 FOG: GAF domain; ANTAR domain-containing protein 3125430 17443559 AFR_14490 Actinoplanes friuliensis DSM 7358 ANTAR domain-containing protein YP_008734233.1 3124723 D 1246995 CDS YP_008734234.1 556565809 17443560 3125547..3126254 1 NC_022657.1 COG2203 FOG: GAF domain; ANTAR domain-containing protein 3126254 17443560 AFR_14495 Actinoplanes friuliensis DSM 7358 ANTAR domain-containing protein YP_008734234.1 3125547 D 1246995 CDS YP_008734235.1 556565810 17443561 3126293..3127024 1 NC_022657.1 COG2203 FOG: GAF domain; hypothetical protein 3127024 17443561 AFR_14500 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734235.1 3126293 D 1246995 CDS YP_008734236.1 556565811 17443562 complement(3127005..3127892) 1 NC_022657.1 COG1396 Predicted transcriptional regulators; helix-turn-helix domain-containing protein 3127892 17443562 AFR_14505 Actinoplanes friuliensis DSM 7358 helix-turn-helix domain-containing protein YP_008734236.1 3127005 R 1246995 CDS YP_008734237.1 556565812 17443563 3128025..3129047 1 NC_022657.1 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases; alcohol dehydrogenase zinc-binding domain-containing protein 3129047 17443563 AFR_14510 Actinoplanes friuliensis DSM 7358 alcohol dehydrogenase zinc-binding domain-containing protein YP_008734237.1 3128025 D 1246995 CDS YP_008734238.1 556565813 17443564 3129311..3130369 1 NC_022657.1 COG1917 Uncharacterized conserved protein, contains double-stranded beta-helix domain; carboxymuconolactone decarboxylase domain /Cupin 2 barrel domain-containing protein 3130369 17443564 AFR_14515 Actinoplanes friuliensis DSM 7358 carboxymuconolactone decarboxylase domain /Cupin 2 barrel domain-containing protein YP_008734238.1 3129311 D 1246995 CDS YP_008734239.1 556565814 17443565 3130489..3130848 1 NC_022657.1 COG4925 Uncharacterized conserved protein; hypothetical protein 3130848 17443565 AFR_14520 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734239.1 3130489 D 1246995 CDS YP_008734240.1 556565815 17443566 complement(3131257..3131544) 1 NC_022657.1 hypothetical protein 3131544 17443566 AFR_14525 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734240.1 3131257 R 1246995 CDS YP_008734241.1 556565816 17443567 complement(3131621..3131902) 1 NC_022657.1 hypothetical protein 3131902 17443567 AFR_14530 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734241.1 3131621 R 1246995 CDS YP_008734242.1 556565817 17443568 complement(3132081..3132284) 1 NC_022657.1 COG1278 Cold shock proteins; putative cold-shock DNA-binding domain protein 3132284 17443568 AFR_14535 Actinoplanes friuliensis DSM 7358 putative cold-shock DNA-binding domain protein YP_008734242.1 3132081 R 1246995 CDS YP_008734243.1 556565818 17443569 3132585..3133163 1 NC_022657.1 COG0262 Dihydrofolate reductase; hypothetical protein 3133163 17443569 AFR_14540 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734243.1 3132585 D 1246995 CDS YP_008734244.1 556565819 17443570 complement(3133174..3134109) 1 NC_022657.1 COG2207 AraC-type DNA-binding domain-containing proteins; AraC family transcriptional regulator 3134109 17443570 AFR_14545 Actinoplanes friuliensis DSM 7358 AraC family transcriptional regulator YP_008734244.1 3133174 R 1246995 CDS YP_008734245.1 556565820 17443571 3134219..3136873 1 NC_022657.1 COG3899 Predicted ATPase; putative LuxR-family transcriptional regulator 3136873 17443571 AFR_14550 Actinoplanes friuliensis DSM 7358 putative LuxR-family transcriptional regulator YP_008734245.1 3134219 D 1246995 CDS YP_008734246.1 556565821 17443572 3136929..3137642 1 NC_022657.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); hypothetical protein 3137642 17443572 AFR_14555 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734246.1 3136929 D 1246995 CDS YP_008734247.1 556565822 17443573 3137639..3138484 1 NC_022657.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); hypothetical protein 3138484 17443573 AFR_14560 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734247.1 3137639 D 1246995 CDS YP_008734248.1 556565823 17443574 3138481..3139296 1 NC_022657.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); hypothetical protein 3139296 17443574 AFR_14565 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734248.1 3138481 D 1246995 CDS YP_008734249.1 556565824 17443575 3139436..3140065 1 NC_022657.1 COG1182 Acyl carrier protein phosphodiesterase; FMN-dependent NADH-azoreductase 3140065 17443575 AFR_14570 Actinoplanes friuliensis DSM 7358 FMN-dependent NADH-azoreductase YP_008734249.1 3139436 D 1246995 CDS YP_008734250.1 556565825 17443576 3140346..3140879 1 NC_022657.1 COG1846 Transcriptional regulators; MarR family transcriptional regulator 3140879 17443576 AFR_14575 Actinoplanes friuliensis DSM 7358 MarR family transcriptional regulator YP_008734250.1 3140346 D 1246995 CDS YP_008734251.1 556565826 17443577 complement(3140892..3141770) 1 NC_022657.1 COG2207 AraC-type DNA-binding domain-containing proteins; AraC family transcriptional regulator 3141770 17443577 AFR_14580 Actinoplanes friuliensis DSM 7358 AraC family transcriptional regulator YP_008734251.1 3140892 R 1246995 CDS YP_008734252.1 556565827 17443578 3141852..3142895 1 NC_022657.1 COG1960 Acyl-CoA dehydrogenases; acyl-CoA dehydrogenase 3142895 17443578 AFR_14585 Actinoplanes friuliensis DSM 7358 acyl-CoA dehydrogenase YP_008734252.1 3141852 D 1246995 CDS YP_008734253.1 556565828 17443579 complement(3142958..3144064) 1 NC_022657.1 COG4608 ABC-type oligopeptide transport system, ATPase component; putative ABC transporter ATP-binding protein 3144064 17443579 AFR_14590 Actinoplanes friuliensis DSM 7358 putative ABC transporter ATP-binding protein YP_008734253.1 3142958 R 1246995 CDS YP_008734254.1 556565829 17443580 complement(3144061..3145038) 1 NC_022657.1 COG0444 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component; oligopeptide/dipeptide ABC transporter ATPase 3145038 17443580 AFR_14595 Actinoplanes friuliensis DSM 7358 oligopeptide/dipeptide ABC transporter ATPase YP_008734254.1 3144061 R 1246995 CDS YP_008734255.1 556565830 17443581 complement(3145050..3146003) 1 NC_022657.1 COG1173 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components; binding-protein-dependent transporters inner membrane component 3146003 17443581 AFR_14600 Actinoplanes friuliensis DSM 7358 binding-protein-dependent transporters inner membrane component YP_008734255.1 3145050 R 1246995 CDS YP_008734256.1 556565831 17443582 complement(3146000..3147007) 1 NC_022657.1 COG0601 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components; ABC transporter permease 3147007 17443582 AFR_14605 Actinoplanes friuliensis DSM 7358 ABC transporter permease YP_008734256.1 3146000 R 1246995 CDS YP_008734257.1 556565832 17443583 complement(3147090..3148748) 1 NC_022657.1 COG0747 ABC-type dipeptide transport system, periplasmic component; putative ABC transporter substrate-binding protein 3148748 17443583 AFR_14610 Actinoplanes friuliensis DSM 7358 putative ABC transporter substrate-binding protein YP_008734257.1 3147090 R 1246995 CDS YP_008734258.1 556565833 17443584 3148979..3150754 1 NC_022657.1 COG1022 Long-chain acyl-CoA synthetases (AMP-forming); AMP-dependent synthetase and ligase 3150754 17443584 AFR_14615 Actinoplanes friuliensis DSM 7358 AMP-dependent synthetase and ligase YP_008734258.1 3148979 D 1246995 CDS YP_008734259.1 556565834 17443585 3150822..3151427 1 NC_022657.1 COG0013 Alanyl-tRNA synthetase; hypothetical protein 3151427 17443585 AFR_14620 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734259.1 3150822 D 1246995 CDS YP_008734260.1 556565835 17443586 complement(3151440..3152063) 1 NC_022657.1 hypothetical protein 3152063 17443586 AFR_14625 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734260.1 3151440 R 1246995 CDS YP_008734261.1 556565836 17443587 3152292..3153653 1 NC_022657.1 COG2059 Chromate transport protein ChrA; Chromate transport protein 3153653 17443587 AFR_14630 Actinoplanes friuliensis DSM 7358 Chromate transport protein YP_008734261.1 3152292 D 1246995 CDS YP_008734262.1 556565837 17443588 complement(3153696..3154376) 1 NC_022657.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); hypothetical protein 3154376 17443588 AFR_14635 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734262.1 3153696 R 1246995 CDS YP_008734263.1 556565838 17443589 complement(3154505..3154861) 1 NC_022657.1 hypothetical protein 3154861 17443589 AFR_14640 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734263.1 3154505 R 1246995 CDS YP_008734264.1 556565839 17443590 complement(3154904..3156784) 1 NC_022657.1 glycoside hydrolase family protein 3156784 17443590 AFR_14645 Actinoplanes friuliensis DSM 7358 glycoside hydrolase family protein YP_008734264.1 3154904 R 1246995 CDS YP_008734265.1 556565840 17443591 complement(3156888..3157871) 1 NC_022657.1 COG2207 AraC-type DNA-binding domain-containing proteins; AraC family transcriptional regulator 3157871 17443591 AFR_14650 Actinoplanes friuliensis DSM 7358 AraC family transcriptional regulator YP_008734265.1 3156888 R 1246995 CDS YP_008734266.1 556565841 17443592 complement(3158070..3158786) 1 NC_022657.1 COG2203 FOG: GAF domain; ANTAR domain-containing protein 3158786 17443592 AFR_14655 Actinoplanes friuliensis DSM 7358 ANTAR domain-containing protein YP_008734266.1 3158070 R 1246995 CDS YP_008734267.1 556565842 17443593 complement(3159199..3160254) 1 NC_022657.1 hypothetical protein 3160254 17443593 AFR_14660 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734267.1 3159199 R 1246995 CDS YP_008734268.1 556565843 17443594 complement(3160275..3161693) 1 NC_022657.1 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases; monooxygenase FAD-binding protein 3161693 17443594 AFR_14665 Actinoplanes friuliensis DSM 7358 monooxygenase FAD-binding protein YP_008734268.1 3160275 R 1246995 CDS YP_008734269.1 556565844 17443595 complement(3162052..3162459) 1 NC_022657.1 hypothetical protein 3162459 17443595 AFR_14670 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734269.1 3162052 R 1246995 CDS YP_008734270.1 556565845 17443596 complement(3162477..3162866) 1 NC_022657.1 putative pyridoxamine 5'-phosphate oxidase-related protein 3162866 17443596 AFR_14675 Actinoplanes friuliensis DSM 7358 putative pyridoxamine 5'-phosphate oxidase-related protein YP_008734270.1 3162477 R 1246995 CDS YP_008734271.1 556565846 17443597 complement(3162881..3163504) 1 NC_022657.1 COG1309 Transcriptional regulator; putative TetR-family transcriptional regulator 3163504 17443597 AFR_14680 Actinoplanes friuliensis DSM 7358 putative TetR-family transcriptional regulator YP_008734271.1 3162881 R 1246995 CDS YP_008734272.1 556565847 17443598 3163562..3164707 1 NC_022657.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); alpha/beta family hydrolase 3164707 17443598 AFR_14685 Actinoplanes friuliensis DSM 7358 alpha/beta family hydrolase YP_008734272.1 3163562 D 1246995 CDS YP_008734273.1 556565848 17443599 3164829..3165668 1 NC_022657.1 hypothetical protein 3165668 17443599 AFR_14690 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734273.1 3164829 D 1246995 CDS YP_008734274.1 556565849 17443600 complement(3165682..3165927) 1 NC_022657.1 hypothetical protein 3165927 17443600 AFR_14695 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734274.1 3165682 R 1246995 CDS YP_008734275.1 556565850 17443601 complement(3166014..3168683) 1 NC_022657.1 COG2771 DNA-binding HTH domain-containing proteins; LuxR family transcriptional regulator 3168683 17443601 AFR_14700 Actinoplanes friuliensis DSM 7358 LuxR family transcriptional regulator YP_008734275.1 3166014 R 1246995 CDS YP_008734276.1 556565851 17443602 complement(3168680..3169312) 1 NC_022657.1 COG1309 Transcriptional regulator; TetR family transcriptional regulator 3169312 17443602 AFR_14705 Actinoplanes friuliensis DSM 7358 TetR family transcriptional regulator YP_008734276.1 3168680 R 1246995 CDS YP_008734277.1 556565852 17443603 3169408..3171222 1 NC_022657.1 COG2132 Putative multicopper oxidases; putative multicopper oxidase 3171222 17443603 AFR_14710 Actinoplanes friuliensis DSM 7358 putative multicopper oxidase YP_008734277.1 3169408 D 1246995 CDS YP_008734278.1 556565853 17443604 3171267..3172295 1 NC_022657.1 COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases; alcohol dehydrogenase 3172295 17443604 AFR_14715 Actinoplanes friuliensis DSM 7358 alcohol dehydrogenase YP_008734278.1 3171267 D 1246995 CDS YP_008734279.1 556565854 17443605 complement(3172318..3172722) 1 NC_022657.1 COG0251 Putative translation initiation inhibitor, yjgF family; endoribonuclease L-PSP 3172722 17443605 AFR_14720 Actinoplanes friuliensis DSM 7358 endoribonuclease L-PSP YP_008734279.1 3172318 R 1246995 CDS YP_008734280.1 556565855 17443606 3172855..3173532 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); short-chain dehydrogenase/reductase SDR 3173532 17443606 AFR_14725 Actinoplanes friuliensis DSM 7358 short-chain dehydrogenase/reductase SDR YP_008734280.1 3172855 D 1246995 CDS YP_008734281.1 556565856 17443607 3173573..3174235 1 NC_022657.1 hypothetical protein 3174235 17443607 AFR_14730 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734281.1 3173573 D 1246995 CDS YP_008734282.1 556565857 17443608 complement(3174232..3175131) 1 NC_022657.1 COG2367 Beta-lactamase class A; beta-lactamase 3175131 17443608 AFR_14735 Actinoplanes friuliensis DSM 7358 beta-lactamase YP_008734282.1 3174232 R 1246995 CDS YP_008734283.1 556565858 17443609 complement(3175128..3175997) 1 NC_022657.1 COG0583 Transcriptional regulator; LysR family transcriptional regulator 3175997 17443609 AFR_14740 Actinoplanes friuliensis DSM 7358 LysR family transcriptional regulator YP_008734283.1 3175128 R 1246995 CDS YP_008734284.1 556565859 17443610 3176143..3176970 1 NC_022657.1 COG2367 Beta-lactamase class A; beta-lactamase 3176970 17443610 AFR_14745 Actinoplanes friuliensis DSM 7358 beta-lactamase YP_008734284.1 3176143 D 1246995 CDS YP_008734285.1 556565860 17443611 complement(3176983..3177603) 1 NC_022657.1 COG0262 Dihydrofolate reductase; bifunctional deaminase-reductase domain-containing protein 3177603 17443611 AFR_14750 Actinoplanes friuliensis DSM 7358 bifunctional deaminase-reductase domain-containing protein YP_008734285.1 3176983 R 1246995 CDS YP_008734286.1 556565861 17443612 complement(3177603..3178082) 1 NC_022657.1 COG3832 Uncharacterized conserved protein; Activator of Hsp90 ATPase 1 family protein 3178082 17443612 AFR_14755 Actinoplanes friuliensis DSM 7358 Activator of Hsp90 ATPase 1 family protein YP_008734286.1 3177603 R 1246995 CDS YP_008734287.1 556565862 17443613 complement(3178086..3178427) 1 NC_022657.1 COG0640 Predicted transcriptional regulators; ArsR family transcriptional regulator 3178427 17443613 AFR_14760 Actinoplanes friuliensis DSM 7358 ArsR family transcriptional regulator YP_008734287.1 3178086 R 1246995 CDS YP_008734288.1 556565863 17443614 complement(3178530..3179558) 1 NC_022657.1 putative glycosyl hydrolase 3179558 17443614 AFR_14765 Actinoplanes friuliensis DSM 7358 putative glycosyl hydrolase YP_008734288.1 3178530 R 1246995 CDS YP_008734289.1 556565864 17443615 3180138..3181541 1 NC_022657.1 putative glycosyl hydrolase 3181541 17443615 AFR_14770 Actinoplanes friuliensis DSM 7358 putative glycosyl hydrolase YP_008734289.1 3180138 D 1246995 CDS YP_008734290.1 556565865 17443616 3181658..3182953 1 NC_022657.1 COG1653 ABC-type sugar transport system, periplasmic component; family 1 extracellular solute-binding protein 3182953 17443616 AFR_14775 Actinoplanes friuliensis DSM 7358 family 1 extracellular solute-binding protein YP_008734290.1 3181658 D 1246995 CDS YP_008734291.1 556565866 17443617 3183044..3183925 1 NC_022657.1 COG1175 ABC-type sugar transport systems, permease components; Maltose or maltodextrin ABC transporter, permease protein MalF 3183925 17443617 AFR_14780 Actinoplanes friuliensis DSM 7358 Maltose or maltodextrin ABC transporter, permease protein MalF YP_008734291.1 3183044 D 1246995 CDS YP_008734292.1 556565867 17443618 3183970..3184785 1 NC_022657.1 COG0395 ABC-type sugar transport system, permease component; Maltose or maltodextrin ABC transporter, permease protein MalG 3184785 17443618 AFR_14785 Actinoplanes friuliensis DSM 7358 Maltose or maltodextrin ABC transporter, permease protein MalG YP_008734292.1 3183970 D 1246995 CDS YP_008734293.1 556565868 17443619 complement(3184834..3186984) 1 NC_022657.1 COG2409 Predicted drug exporters of the RND superfamily; membrane transport protein 3186984 17443619 AFR_14790 Actinoplanes friuliensis DSM 7358 membrane transport protein YP_008734293.1 3184834 R 1246995 CDS YP_008734294.1 556565869 17443620 complement(3187011..3187430) 1 NC_022657.1 DoxX family protein 3187430 17443620 AFR_14795 Actinoplanes friuliensis DSM 7358 DoxX family protein YP_008734294.1 3187011 R 1246995 CDS YP_008734295.1 556565870 17443621 complement(3187478..3188035) 1 NC_022657.1 hypothetical protein 3188035 17443621 AFR_14800 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734295.1 3187478 R 1246995 CDS YP_008734296.1 556565871 17443622 3188182..3189378 1 NC_022657.1 COG4585 Signal transduction histidine kinase; integral membrane sensor signal transduction histidine kinase 3189378 17443622 AFR_14805 Actinoplanes friuliensis DSM 7358 integral membrane sensor signal transduction histidine kinase YP_008734296.1 3188182 D 1246995 CDS YP_008734297.1 556565872 17443623 3189375..3190058 1 NC_022657.1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; putative two-component system response regulator 3190058 17443623 AFR_14810 Actinoplanes friuliensis DSM 7358 putative two-component system response regulator YP_008734297.1 3189375 D 1246995 CDS YP_008734298.1 556565873 17443624 3190152..3191168 1 NC_022657.1 COG3291 FOG: PKD repeat; collagenase 3191168 17443624 AFR_14815 Actinoplanes friuliensis DSM 7358 collagenase YP_008734298.1 3190152 D 1246995 CDS YP_008734299.1 556565874 17443625 complement(3191213..3191389) 1 NC_022657.1 COG5466 Predicted small metal-binding protein; hypothetical protein 3191389 17443625 AFR_14820 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734299.1 3191213 R 1246995 CDS YP_008734300.1 556565875 17443626 complement(3191364..3191990) 1 NC_022657.1 COG1309 Transcriptional regulator; yvdT-like transcriptional regulator 3191990 17443626 AFR_14825 Actinoplanes friuliensis DSM 7358 yvdT-like transcriptional regulator YP_008734300.1 3191364 R 1246995 CDS YP_008734301.1 556565876 17443627 3192074..3192946 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); short-chain dehydrogenase/reductase SDR 3192946 17443627 AFR_14830 Actinoplanes friuliensis DSM 7358 short-chain dehydrogenase/reductase SDR YP_008734301.1 3192074 D 1246995 CDS YP_008734302.1 556565877 17443628 complement(3192934..3193488) 1 NC_022657.1 hypothetical protein 3193488 17443628 AFR_14835 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734302.1 3192934 R 1246995 CDS YP_008734303.1 556565878 17443629 complement(3193500..3195071) 1 NC_022657.1 COG0515 Serine/threonine protein kinase; WD-40 repeat-containing serine/threonine protein kinase 3195071 17443629 AFR_14840 Actinoplanes friuliensis DSM 7358 WD-40 repeat-containing serine/threonine protein kinase YP_008734303.1 3193500 R 1246995 CDS YP_008734304.1 556565879 17443630 complement(3195158..3196093) 1 NC_022657.1 COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases; NADPH:quinone reductase-related Zn-dependent oxidoreductase 3196093 17443630 AFR_14845 Actinoplanes friuliensis DSM 7358 NADPH:quinone reductase-related Zn-dependent oxidoreductase YP_008734304.1 3195158 R 1246995 CDS YP_008734305.1 556565880 17443631 complement(3196202..3197026) 1 NC_022657.1 COG1396 Predicted transcriptional regulators; XRE family transcriptional regulator 3197026 17443631 AFR_14850 Actinoplanes friuliensis DSM 7358 XRE family transcriptional regulator YP_008734305.1 3196202 R 1246995 CDS YP_008734306.1 556565881 17443632 complement(3197134..3197784) 1 NC_022657.1 COG3576 Predicted flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase; pyridoxine 5`-phosphate oxidase 3197784 17443632 AFR_14855 Actinoplanes friuliensis DSM 7358 pyridoxine 5`-phosphate oxidase YP_008734306.1 3197134 R 1246995 CDS YP_008734307.1 556565882 17443633 3197948..3198673 1 NC_022657.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); alpha/beta hydrolase fold protein 3198673 17443633 AFR_14860 Actinoplanes friuliensis DSM 7358 alpha/beta hydrolase fold protein YP_008734307.1 3197948 D 1246995 CDS YP_008734308.1 556565883 17443634 complement(3198670..3201792) 1 NC_022657.1 COG3899 Predicted ATPase; transcriptional regulator 3201792 17443634 AFR_14865 Actinoplanes friuliensis DSM 7358 transcriptional regulator YP_008734308.1 3198670 R 1246995 CDS YP_008734309.1 556565884 17443635 3201883..3202614 1 NC_022657.1 COG0457 FOG: TPR repeat; hypothetical protein 3202614 17443635 AFR_14870 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734309.1 3201883 D 1246995 CDS YP_008734310.1 556565885 17443636 3202640..3203482 1 NC_022657.1 COG2207 AraC-type DNA-binding domain-containing proteins; helix-turn-helix domain-containing protein 3203482 17443636 AFR_14875 Actinoplanes friuliensis DSM 7358 helix-turn-helix domain-containing protein YP_008734310.1 3202640 D 1246995 CDS YP_008734311.1 556565886 17443637 3203611..3204522 1 NC_022657.1 COG0657 Esterase/lipase; alpha/beta hydrolase domain-containing protein 3204522 17443637 AFR_14880 Actinoplanes friuliensis DSM 7358 alpha/beta hydrolase domain-containing protein YP_008734311.1 3203611 D 1246995 CDS YP_008734312.1 556565887 17443638 complement(3204536..3205471) 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); short chain dehydrogenase 3205471 17443638 AFR_14885 Actinoplanes friuliensis DSM 7358 short chain dehydrogenase YP_008734312.1 3204536 R 1246995 CDS YP_008734313.1 556565888 17443639 complement(3205585..3206445) 1 NC_022657.1 COG1396 Predicted transcriptional regulators; XRE family transcriptional regulator 3206445 17443639 AFR_14890 Actinoplanes friuliensis DSM 7358 XRE family transcriptional regulator YP_008734313.1 3205585 R 1246995 CDS YP_008734314.1 556565889 17443640 complement(3206582..3207841) 1 NC_022657.1 COG3509 Poly(3-hydroxybutyrate) depolymerase; cellulose-binding family ii 3207841 17443640 AFR_14895 Actinoplanes friuliensis DSM 7358 cellulose-binding family ii YP_008734314.1 3206582 R 1246995 CDS YP_008734315.1 556565890 17443641 complement(3207858..3209231) 1 NC_022657.1 cellulose-binding family II 3209231 17443641 AFR_14900 Actinoplanes friuliensis DSM 7358 cellulose-binding family II YP_008734315.1 3207858 R 1246995 CDS YP_008734316.1 556565891 17443642 complement(3209305..3211233) 1 NC_022657.1 COG3507 Beta-xylosidase; putative glycosyl hydrolase 3211233 17443642 AFR_14905 Actinoplanes friuliensis DSM 7358 putative glycosyl hydrolase YP_008734316.1 3209305 R 1246995 CDS YP_008734317.1 556565892 17443643 complement(3211313..3212647) 1 NC_022657.1 COG3693 Beta-1,4-xylanase; putative xylanase 3212647 17443643 AFR_14910 Actinoplanes friuliensis DSM 7358 putative xylanase YP_008734317.1 3211313 R 1246995 CDS YP_008734318.1 556565893 17443644 3212970..3214613 1 NC_022657.1 ECF subfamily RNA polymerase sigma-24 subunit 3214613 17443644 AFR_14915 Actinoplanes friuliensis DSM 7358 ECF subfamily RNA polymerase sigma-24 subunit YP_008734318.1 3212970 D 1246995 CDS YP_008734319.1 556565894 17443645 complement(3214614..3214847) 1 NC_022657.1 hypothetical protein 3214847 17443645 AFR_14920 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734319.1 3214614 R 1246995 CDS YP_008734320.1 556565895 17443646 3215149..3216264 1 NC_022657.1 COG5184 Alpha-tubulin suppressor and related RCC1 domain-containing proteins; regulator of chromosome condensation RCC1 3216264 17443646 AFR_14925 Actinoplanes friuliensis DSM 7358 regulator of chromosome condensation RCC1 YP_008734320.1 3215149 D 1246995 CDS YP_008734321.1 556565896 17443647 3216417..3217940 1 NC_022657.1 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; ECF subfamily RNA polymerase sigma-24 subunit 3217940 17443647 AFR_14930 Actinoplanes friuliensis DSM 7358 ECF subfamily RNA polymerase sigma-24 subunit YP_008734321.1 3216417 D 1246995 CDS YP_008734322.1 556565897 17443648 complement(3217937..3219544) 1 NC_022657.1 COG0515 Serine/threonine protein kinase; serine/threonine protein kinase 3219544 17443648 AFR_14935 Actinoplanes friuliensis DSM 7358 serine/threonine protein kinase YP_008734322.1 3217937 R 1246995 CDS YP_008734323.1 556565898 17443649 complement(3219623..3220783) 1 NC_022657.1 COG1940 Transcriptional regulator/sugar kinase; ROK family protein 3220783 17443649 AFR_14940 Actinoplanes friuliensis DSM 7358 ROK family protein YP_008734323.1 3219623 R 1246995 CDS YP_008734324.1 556565899 17443650 complement(3220835..3222331) 1 NC_022657.1 COG3345 Alpha-galactosidase; alpha-galactosidase 3222331 17443650 AFR_14945 Actinoplanes friuliensis DSM 7358 alpha-galactosidase YP_008734324.1 3220835 R 1246995 CDS YP_008734325.1 556565900 17443651 complement(3222409..3223740) 1 NC_022657.1 COG1653 ABC-type sugar transport system, periplasmic component; extracellular solute-binding protein family 1 protein 3223740 17443651 AFR_14950 Actinoplanes friuliensis DSM 7358 extracellular solute-binding protein family 1 protein YP_008734325.1 3222409 R 1246995 CDS YP_008734326.1 556565901 17443652 complement(3223772..3224656) 1 NC_022657.1 COG0395 ABC-type sugar transport system, permease component; binding-protein-dependent transport system inner membrane protein 3224656 17443652 AFR_14955 Actinoplanes friuliensis DSM 7358 binding-protein-dependent transport system inner membrane protein YP_008734326.1 3223772 R 1246995 CDS YP_008734327.1 556565902 17443653 complement(3224669..3225550) 1 NC_022657.1 COG1175 ABC-type sugar transport systems, permease components; binding-protein-dependent transport protein 3225550 17443653 AFR_14960 Actinoplanes friuliensis DSM 7358 binding-protein-dependent transport protein YP_008734327.1 3224669 R 1246995 CDS YP_008734328.1 556565903 17443654 3225712..3227643 1 NC_022657.1 carbohydrate binding family 6 3227643 17443654 AFR_14965 Actinoplanes friuliensis DSM 7358 carbohydrate binding family 6 YP_008734328.1 3225712 D 1246995 CDS YP_008734329.1 556565904 17443655 3227653..3228996 1 NC_022657.1 hypothetical protein 3228996 17443655 AFR_14970 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734329.1 3227653 D 1246995 CDS YP_008734330.1 556565905 17443656 3228993..3230012 1 NC_022657.1 COG1085 Galactose-1-phosphate uridylyltransferase; galactose-1-phosphate uridylyltransferase 3230012 17443656 AFR_14975 Actinoplanes friuliensis DSM 7358 galactose-1-phosphate uridylyltransferase YP_008734330.1 3228993 D 1246995 CDS YP_008734331.1 556565906 17443657 complement(3230063..3233443) 1 NC_022657.1 COG2133 Glucose/sorbosone dehydrogenases; hypothetical protein 3233443 17443657 AFR_14980 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734331.1 3230063 R 1246995 CDS YP_008734332.1 556565907 17443658 3233715..3234947 1 NC_022657.1 COG3434 Predicted signal transduction protein containing EAL and modified HD-GYP domains; hypothetical protein 3234947 17443658 AFR_14985 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734332.1 3233715 D 1246995 CDS YP_008734333.1 556565908 17443659 complement(3234954..3235559) 1 NC_022657.1 COG2085 Predicted dinucleotide-binding enzymes; glycerol-3-phosphate dehydrogenase 3235559 17443659 AFR_14990 Actinoplanes friuliensis DSM 7358 glycerol-3-phosphate dehydrogenase YP_008734333.1 3234954 R 1246995 CDS YP_008734334.1 556565909 17443660 3235652..3236449 1 NC_022657.1 hypothetical protein 3236449 17443660 AFR_14995 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734334.1 3235652 D 1246995 CDS YP_008734335.1 556565910 17443661 3236499..3236921 1 NC_022657.1 hypothetical protein 3236921 17443661 AFR_15000 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734335.1 3236499 D 1246995 CDS YP_008734336.1 556565911 17443662 3237051..3237848 1 NC_022657.1 COG0491 Zn-dependent hydrolases, including glyoxylases; Zn-dependent hydrolase 3237848 17443662 AFR_15005 Actinoplanes friuliensis DSM 7358 Zn-dependent hydrolase YP_008734336.1 3237051 D 1246995 CDS YP_008734337.1 556565912 17443663 3237845..3238237 1 NC_022657.1 COG0599 Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit; carboxymuconolactone decarboxylase 3238237 17443663 AFR_15010 Actinoplanes friuliensis DSM 7358 carboxymuconolactone decarboxylase YP_008734337.1 3237845 D 1246995 CDS YP_008734338.1 556565913 17443664 3238239..3239282 1 NC_022657.1 COG3055 Uncharacterized protein conserved in bacteria; Kelch repeat-containing protein 3239282 17443664 AFR_15015 Actinoplanes friuliensis DSM 7358 Kelch repeat-containing protein YP_008734338.1 3238239 D 1246995 CDS YP_008734339.1 556565914 17443665 complement(3239288..3239761) 1 NC_022657.1 COG1846 Transcriptional regulators; MarR family transcriptional regulator 3239761 17443665 AFR_15020 Actinoplanes friuliensis DSM 7358 MarR family transcriptional regulator YP_008734339.1 3239288 R 1246995 CDS YP_008734340.1 556565915 17443666 3239962..3240972 1 NC_022657.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); epoxide hydrolase 3240972 17443666 AFR_15025 Actinoplanes friuliensis DSM 7358 epoxide hydrolase YP_008734340.1 3239962 D 1246995 CDS YP_008734341.1 556565916 17443667 3241113..3242048 1 NC_022657.1 hypothetical protein 3242048 17443667 AFR_15030 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734341.1 3241113 D 1246995 CDS YP_008734342.1 556565917 17443668 complement(3242045..3244072) 1 NC_022657.1 hypothetical protein 3244072 17443668 AFR_15035 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734342.1 3242045 R 1246995 CDS YP_008734343.1 556565918 17443669 3244171..3244932 1 NC_022657.1 hypothetical protein 3244932 17443669 AFR_15040 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734343.1 3244171 D 1246995 CDS YP_008734344.1 556565919 17443670 complement(3244936..3246018) 1 NC_022657.1 COG0642 Signal transduction histidine kinase; histidine kinase 3246018 17443670 AFR_15045 Actinoplanes friuliensis DSM 7358 histidine kinase YP_008734344.1 3244936 R 1246995 CDS YP_008734345.1 556565920 17443671 complement(3246015..3246677) 1 NC_022657.1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; two-component system response regulator 3246677 17443671 AFR_15050 Actinoplanes friuliensis DSM 7358 two-component system response regulator YP_008734345.1 3246015 R 1246995 CDS YP_008734346.1 556565921 17443672 3246791..3247540 1 NC_022657.1 COG1131 ABC-type multidrug transport system, ATPase component; lantibiotic transport ATP-binding protein 3247540 17443672 AFR_15055 Actinoplanes friuliensis DSM 7358 lantibiotic transport ATP-binding protein YP_008734346.1 3246791 D 1246995 CDS YP_008734347.1 556565922 17443673 3247540..3248964 1 NC_022657.1 COG2848 Uncharacterized conserved protein; hypothetical protein 3248964 17443673 AFR_15060 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734347.1 3247540 D 1246995 CDS YP_008734348.1 556565923 17443674 3248961..3249689 1 NC_022657.1 hypothetical protein 3249689 17443674 AFR_15065 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734348.1 3248961 D 1246995 CDS YP_008734349.1 556565924 17443675 3249715..3250125 1 NC_022657.1 hypothetical protein 3250125 17443675 AFR_15070 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734349.1 3249715 D 1246995 CDS YP_008734350.1 556565925 17443676 3250206..3251171 1 NC_022657.1 hypothetical protein 3251171 17443676 AFR_15075 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734350.1 3250206 D 1246995 CDS YP_008734351.1 556565926 17443677 complement(3251184..3251741) 1 NC_022657.1 ricin B lectin 3251741 17443677 AFR_15080 Actinoplanes friuliensis DSM 7358 ricin B lectin YP_008734351.1 3251184 R 1246995 CDS YP_008734352.1 556565927 17443678 complement(3251770..3253023) 1 NC_022657.1 COG4941 Predicted RNA polymerase sigma factor containing a TPR repeat domain; putative ECF subfamily RNA polymerase sigma-24 subunit 3253023 17443678 AFR_15085 Actinoplanes friuliensis DSM 7358 putative ECF subfamily RNA polymerase sigma-24 subunit YP_008734352.1 3251770 R 1246995 CDS YP_008734353.1 556565928 17443679 complement(3253020..3253343) 1 NC_022657.1 COG3795 Uncharacterized protein conserved in bacteria; YCII-like protein 3253343 17443679 AFR_15090 Actinoplanes friuliensis DSM 7358 YCII-like protein YP_008734353.1 3253020 R 1246995 CDS YP_008734354.1 556565929 17443680 3253499..3254431 1 NC_022657.1 COG1957 Inosine-uridine nucleoside N-ribohydrolase; ribosylpyrimidine nucleosidase 3254431 17443680 AFR_15095 Actinoplanes friuliensis DSM 7358 ribosylpyrimidine nucleosidase YP_008734354.1 3253499 D 1246995 CDS YP_008734355.1 556565930 17443681 complement(3254416..3255186) 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); short-chain dehydrogenase/reductase SDR 3255186 17443681 AFR_15100 Actinoplanes friuliensis DSM 7358 short-chain dehydrogenase/reductase SDR YP_008734355.1 3254416 R 1246995 CDS YP_008734356.1 556565931 17443682 3255354..3256331 1 NC_022657.1 COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases); aldo/keto reductase 3256331 17443682 AFR_15105 Actinoplanes friuliensis DSM 7358 aldo/keto reductase YP_008734356.1 3255354 D 1246995 CDS YP_008734357.1 556565932 17443683 3256486..3257439 1 NC_022657.1 COG1064 Zn-dependent alcohol dehydrogenases; alcohol dehydrogenase (NADP+) 3257439 17443683 AFR_15110 Actinoplanes friuliensis DSM 7358 alcohol dehydrogenase (NADP+) YP_008734357.1 3256486 D 1246995 CDS YP_008734358.1 556565933 17443684 complement(3257436..3258029) 1 NC_022657.1 COG2910 Putative NADH-flavin reductase; NAD-dependent epimerase/dehydratase 3258029 17443684 AFR_15115 Actinoplanes friuliensis DSM 7358 NAD-dependent epimerase/dehydratase YP_008734358.1 3257436 R 1246995 CDS YP_008734359.1 556565934 17443685 3258123..3258470 1 NC_022657.1 COG1733 Predicted transcriptional regulators; hypothetical protein 3258470 17443685 AFR_15120 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734359.1 3258123 D 1246995 CDS YP_008734360.1 556565935 17443686 complement(3258455..3259060) 1 NC_022657.1 COG1309 Transcriptional regulator; TetR family transcriptional regulator 3259060 17443686 AFR_15125 Actinoplanes friuliensis DSM 7358 TetR family transcriptional regulator YP_008734360.1 3258455 R 1246995 CDS YP_008734361.1 556565936 17443687 3259155..3260051 1 NC_022657.1 COG1131 ABC-type multidrug transport system, ATPase component; multidrug ABC transporter ATPase 3260051 17443687 AFR_15130 Actinoplanes friuliensis DSM 7358 multidrug ABC transporter ATPase YP_008734361.1 3259155 D 1246995 CDS YP_008734362.1 556565937 17443688 3260048..3260794 1 NC_022657.1 hypothetical protein 3260794 17443688 AFR_15135 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734362.1 3260048 D 1246995 CDS YP_008734363.1 556565938 17443689 3261040..3264090 1 NC_022657.1 COG3250 Beta-galactosidase/beta-glucuronidase; putative glycosyl hydrolase 3264090 17443689 AFR_15140 Actinoplanes friuliensis DSM 7358 putative glycosyl hydrolase YP_008734363.1 3261040 D 1246995 CDS YP_008734364.1 556565939 17443690 complement(3264151..3264990) 1 NC_022657.1 COG0583 Transcriptional regulator; LysR family transcriptional regulator 3264990 17443690 AFR_15145 Actinoplanes friuliensis DSM 7358 LysR family transcriptional regulator YP_008734364.1 3264151 R 1246995 CDS YP_008734365.1 556565940 17443691 3265082..3265429 1 NC_022657.1 COG4334 Uncharacterized protein conserved in bacteria; hypothetical protein 3265429 17443691 AFR_15150 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734365.1 3265082 D 1246995 CDS YP_008734366.1 556565941 17443692 complement(3265431..3265775) 1 NC_022657.1 hypothetical protein 3265775 17443692 AFR_15155 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734366.1 3265431 R 1246995 CDS YP_008734367.1 556565942 17443693 3266067..3267146 1 NC_022657.1 COG5479 Uncharacterized protein potentially involved in peptidoglycan biosynthesis; N-acetylmuramoyl-L-alanine amidase family 2 protein 3267146 17443693 AFR_15160 Actinoplanes friuliensis DSM 7358 N-acetylmuramoyl-L-alanine amidase family 2 protein YP_008734367.1 3266067 D 1246995 CDS YP_008734368.1 556565943 17443694 complement(3267163..3268104) 1 NC_022657.1 COG2354 Uncharacterized protein conserved in bacteria; hypothetical protein 3268104 17443694 AFR_15165 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734368.1 3267163 R 1246995 CDS YP_008734369.1 556565944 17443695 complement(3268159..3268620) 1 NC_022657.1 hypothetical protein 3268620 17443695 AFR_15170 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734369.1 3268159 R 1246995 CDS YP_008734370.1 556565945 17443696 complement(3268675..3269217) 1 NC_022657.1 COG1881 Phospholipid-binding protein; phospholipid-binding protein 3269217 17443696 AFR_15175 Actinoplanes friuliensis DSM 7358 phospholipid-binding protein YP_008734370.1 3268675 R 1246995 CDS YP_008734371.1 556565946 17443697 3269275..3269940 1 NC_022657.1 COG1802 Transcriptional regulators; GntR family transcriptional regulator 3269940 17443697 AFR_15180 Actinoplanes friuliensis DSM 7358 GntR family transcriptional regulator YP_008734371.1 3269275 D 1246995 CDS YP_008734372.1 556565947 17443698 complement(3269920..3270876) 1 NC_022657.1 COG2378 Predicted transcriptional regulator; helix-turn-helix type 11 domain-containing protein 3270876 17443698 AFR_15185 Actinoplanes friuliensis DSM 7358 helix-turn-helix type 11 domain-containing protein YP_008734372.1 3269920 R 1246995 CDS YP_008734373.1 556565948 17443699 3270971..3271375 1 NC_022657.1 COG0346 Lactoylglutathione lyase and related lyases; hypothetical protein 3271375 17443699 AFR_15190 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734373.1 3270971 D 1246995 CDS YP_008734374.1 556565949 17443700 3271436..3272902 1 NC_022657.1 COG3211 Predicted phosphatase; hypothetical protein 3272902 17443700 AFR_15195 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734374.1 3271436 D 1246995 CDS YP_008734375.1 556565950 17443701 complement(3272919..3273752) 1 NC_022657.1 COG1752 Predicted esterase of the alpha-beta hydrolase superfamily; Patatin 3273752 17443701 AFR_15200 Actinoplanes friuliensis DSM 7358 Patatin YP_008734375.1 3272919 R 1246995 CDS YP_008734376.1 556565951 17443702 complement(3273788..3275857) 1 NC_022657.1 COG3511 Phospholipase C; phospholipase C 3275857 17443702 AFR_15205 Actinoplanes friuliensis DSM 7358 phospholipase C YP_008734376.1 3273788 R 1246995 CDS YP_008734377.1 556565952 17443703 complement(3276029..3277213) 1 NC_022657.1 COG1533 DNA repair photolyase; hypothetical protein 3277213 17443703 AFR_15210 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734377.1 3276029 R 1246995 CDS YP_008734378.1 556565953 17443704 3277301..3278227 1 NC_022657.1 hypothetical protein 3278227 17443704 AFR_15215 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734378.1 3277301 D 1246995 CDS YP_008734379.1 556565954 17443705 complement(3278270..3279166) 1 NC_022657.1 COG3386 Gluconolactonase; lactone hydrolase 3279166 17443705 AFR_15220 Actinoplanes friuliensis DSM 7358 lactone hydrolase YP_008734379.1 3278270 R 1246995 CDS YP_008734380.1 556565955 17443706 complement(3279105..3280310) 1 NC_022657.1 COG4292 Predicted membrane protein; low temperature protein 3280310 17443706 AFR_15225 Actinoplanes friuliensis DSM 7358 low temperature protein YP_008734380.1 3279105 R 1246995 CDS YP_008734381.1 556565956 17443707 complement(3280343..3280942) 1 NC_022657.1 COG3963 Phospholipid N-methyltransferase; ribosomal RNA adenine dimethylase 3280942 17443707 AFR_15230 Actinoplanes friuliensis DSM 7358 ribosomal RNA adenine dimethylase YP_008734381.1 3280343 R 1246995 CDS YP_008734382.1 556565957 17443708 complement(3280939..3281901) 1 NC_022657.1 COG0657 Esterase/lipase; esterase LipW 3281901 17443708 AFR_15235 Actinoplanes friuliensis DSM 7358 esterase LipW YP_008734382.1 3280939 R 1246995 CDS YP_008734383.1 556565958 17443709 complement(3281934..3282239) 1 NC_022657.1 COG1359 Uncharacterized conserved protein; hypothetical protein 3282239 17443709 AFR_15240 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734383.1 3281934 R 1246995 CDS YP_008734384.1 556565959 17443710 complement(3282388..3283287) 1 NC_022657.1 COG2207 AraC-type DNA-binding domain-containing proteins; Shy25-AraC-family transcriptional regulator 3283287 17443710 AFR_15245 Actinoplanes friuliensis DSM 7358 Shy25-AraC-family transcriptional regulator YP_008734384.1 3282388 R 1246995 CDS YP_008734385.1 556565960 17443711 complement(3283355..3284578) 1 NC_022657.1 hypothetical protein 3284578 17443711 AFR_15250 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734385.1 3283355 R 1246995 CDS YP_008734386.1 556565961 17443712 complement(3284575..3285105) 1 NC_022657.1 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; putative RNA polymerase ECF-subfamily sigma factor 3285105 17443712 AFR_15255 Actinoplanes friuliensis DSM 7358 putative RNA polymerase ECF-subfamily sigma factor YP_008734386.1 3284575 R 1246995 CDS YP_008734387.1 556565962 17443713 complement(3285499..3285780) 1 NC_022657.1 hypothetical protein 3285780 17443713 AFR_15260 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734387.1 3285499 R 1246995 CDS YP_008734388.1 556565963 17443714 3285977..3286432 1 NC_022657.1 COG0735 Fe2+/Zn2+ uptake regulation proteins; Fur family ferric uptake regulator 3286432 17443714 AFR_15265 Actinoplanes friuliensis DSM 7358 Fur family ferric uptake regulator YP_008734388.1 3285977 D 1246995 CDS YP_008734389.1 556565964 17443715 3286429..3288702 1 NC_022657.1 COG0376 Catalase (peroxidase I); catalase/hydroperoxidase HPI(I) 3288702 17443715 AFR_15270 Actinoplanes friuliensis DSM 7358 catalase/hydroperoxidase HPI(I) YP_008734389.1 3286429 D 1246995 CDS YP_008734390.1 556565965 17443716 complement(3288762..3289562) 1 NC_022657.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); hydrolase 3289562 17443716 AFR_15275 Actinoplanes friuliensis DSM 7358 hydrolase YP_008734390.1 3288762 R 1246995 CDS YP_008734391.1 556565966 17443717 3289563..3290018 1 NC_022657.1 COG1733 Predicted transcriptional regulators; HxlR family transcriptional regulator 3290018 17443717 AFR_15280 Actinoplanes friuliensis DSM 7358 HxlR family transcriptional regulator YP_008734391.1 3289563 D 1246995 CDS YP_008734392.1 556565967 17443718 complement(3290027..3290314) 1 NC_022657.1 hypothetical protein 3290314 17443718 AFR_15285 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734392.1 3290027 R 1246995 CDS YP_008734393.1 556565968 17443719 complement(3290376..3291377) 1 NC_022657.1 COG4124 Beta-mannanase; mannan endo-1,4-beta-mannosidase 3291377 17443719 AFR_15290 Actinoplanes friuliensis DSM 7358 mannan endo-1,4-beta-mannosidase YP_008734393.1 3290376 R 1246995 CDS YP_008734394.1 556565969 17443720 complement(3291390..3294122) 1 NC_022657.1 COG3250 Beta-galactosidase/beta-glucuronidase; beta-mannosidase 3294122 17443720 AFR_15295 Actinoplanes friuliensis DSM 7358 beta-mannosidase YP_008734394.1 3291390 R 1246995 CDS YP_008734395.1 556565970 17443721 complement(3294119..3294940) 1 NC_022657.1 COG0395 ABC-type sugar transport system, permease component; ABC transporter permease 3294940 17443721 AFR_15300 Actinoplanes friuliensis DSM 7358 ABC transporter permease YP_008734395.1 3294119 R 1246995 CDS YP_008734396.1 556565971 17443722 complement(3294937..3295800) 1 NC_022657.1 COG1175 ABC-type sugar transport systems, permease components; sn-glycerol-3-phosphate transport system permease protein ugpA 3295800 17443722 AFR_15305 Actinoplanes friuliensis DSM 7358 sn-glycerol-3-phosphate transport system permease protein ugpA YP_008734396.1 3294937 R 1246995 CDS YP_008734397.1 556565972 17443723 complement(3295797..3297092) 1 NC_022657.1 COG1653 ABC-type sugar transport system, periplasmic component; putative ABC transporter substrate-binding protein 3297092 17443723 AFR_15310 Actinoplanes friuliensis DSM 7358 putative ABC transporter substrate-binding protein YP_008734397.1 3295797 R 1246995 CDS YP_008734398.1 556565973 17443724 complement(3297221..3298048) 1 NC_022657.1 COG1609 Transcriptional regulators; HTH-type transcriptional repressor purR 3298048 17443724 AFR_15315 Actinoplanes friuliensis DSM 7358 HTH-type transcriptional repressor purR YP_008734398.1 3297221 R 1246995 CDS YP_008734399.1 556565974 17443725 3298142..3299266 1 NC_022657.1 COG1940 Transcriptional regulator/sugar kinase; Putative xylose repressor 3299266 17443725 AFR_15320 Actinoplanes friuliensis DSM 7358 Putative xylose repressor YP_008734399.1 3298142 D 1246995 CDS YP_008734400.1 556565975 17443726 3299323..3300009 1 NC_022657.1 hypothetical protein 3300009 17443726 AFR_15325 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734400.1 3299323 D 1246995 CDS YP_008734401.1 556565976 17443727 3300099..3300512 1 NC_022657.1 hypothetical protein 3300512 17443727 AFR_15330 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734401.1 3300099 D 1246995 CDS YP_008734402.1 556565977 17443728 3300595..3301014 1 NC_022657.1 hypothetical protein 3301014 17443728 AFR_15335 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734402.1 3300595 D 1246995 CDS YP_008734403.1 556565978 17443729 complement(3301016..3301891) 1 NC_022657.1 COG1396 Predicted transcriptional regulators; XRE family transcriptional regulator 3301891 17443729 AFR_15340 Actinoplanes friuliensis DSM 7358 XRE family transcriptional regulator YP_008734403.1 3301016 R 1246995 CDS YP_008734404.1 556565979 17443730 3301963..3302949 1 NC_022657.1 COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases; alcohol dehydrogenase 3302949 17443730 AFR_15345 Actinoplanes friuliensis DSM 7358 alcohol dehydrogenase YP_008734404.1 3301963 D 1246995 CDS YP_008734405.1 556565980 17443731 complement(3302933..3305674) 1 NC_022657.1 COG1112 Superfamily I DNA and RNA helicases and helicase subunits; hypothetical protein 3305674 17443731 AFR_15350 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734405.1 3302933 R 1246995 CDS YP_008734406.1 556565981 17443732 complement(3305709..3308456) 1 NC_022657.1 COG0744 Membrane carboxypeptidase (penicillin-binding protein); glycosyl transferase family protein 3308456 17443732 AFR_15355 Actinoplanes friuliensis DSM 7358 glycosyl transferase family protein YP_008734406.1 3305709 R 1246995 CDS YP_008734407.1 556565982 17443733 complement(3308608..3309450) 1 NC_022657.1 COG1396 Predicted transcriptional regulators; XRE family transcriptional regulator 3309450 17443733 AFR_15360 Actinoplanes friuliensis DSM 7358 XRE family transcriptional regulator YP_008734407.1 3308608 R 1246995 CDS YP_008734408.1 556565983 17443734 complement(3309514..3310077) 1 NC_022657.1 hypothetical protein 3310077 17443734 AFR_15365 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734408.1 3309514 R 1246995 CDS YP_008734409.1 556565984 17443735 complement(3310148..3311752) 1 NC_022657.1 COG0477 Permeases of the major facilitator superfamily; ykuC-like MFS-type transporter 3311752 17443735 AFR_15370 Actinoplanes friuliensis DSM 7358 ykuC-like MFS-type transporter YP_008734409.1 3310148 R 1246995 CDS YP_008734410.1 556565985 17443736 3311854..3312753 1 NC_022657.1 COG1131 ABC-type multidrug transport system, ATPase component; spermidine/putrescine import ATP-binding protein potA 3312753 17443736 AFR_15375 Actinoplanes friuliensis DSM 7358 spermidine/putrescine import ATP-binding protein potA YP_008734410.1 3311854 D 1246995 CDS YP_008734411.1 556565986 17443737 3312750..3313352 1 NC_022657.1 hypothetical protein 3313352 17443737 AFR_15380 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734411.1 3312750 D 1246995 CDS YP_008734412.1 556565987 17443738 complement(3313355..3314284) 1 NC_022657.1 COG1808 Predicted membrane protein; hypothetical protein 3314284 17443738 AFR_15385 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734412.1 3313355 R 1246995 CDS YP_008734413.1 556565988 17443739 3314359..3315834 1 NC_022657.1 COG2199 FOG: GGDEF domain; hypothetical protein 3315834 17443739 AFR_15390 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734413.1 3314359 D 1246995 CDS YP_008734414.1 556565989 17443740 3315888..3316472 1 NC_022657.1 hypothetical protein 3316472 17443740 AFR_15395 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734414.1 3315888 D 1246995 CDS YP_008734415.1 556565990 17443741 complement(3316420..3316803) 1 NC_022657.1 glyoxalase/bleomycin resistance protein/dioxygenase 3316803 17443741 AFR_15400 Actinoplanes friuliensis DSM 7358 glyoxalase/bleomycin resistance protein/dioxygenase YP_008734415.1 3316420 R 1246995 CDS YP_008734416.1 556565991 17443742 3316857..3317570 1 NC_022657.1 COG0708 Exonuclease III; hypothetical protein 3317570 17443742 AFR_15405 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734416.1 3316857 D 1246995 CDS YP_008734417.1 556565992 17443743 3317725..3318054 1 NC_022657.1 hypothetical protein 3318054 17443743 AFR_15410 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734417.1 3317725 D 1246995 CDS YP_008734418.1 556565993 17443744 3318133..3319344 1 NC_022657.1 COG1073 Hydrolases of the alpha/beta superfamily; hypothetical protein 3319344 17443744 AFR_15415 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734418.1 3318133 D 1246995 CDS YP_008734419.1 556565994 17443745 complement(3319411..3319938) 1 NC_022657.1 hypothetical protein 3319938 17443745 AFR_15420 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734419.1 3319411 R 1246995 CDS YP_008734420.1 556565995 17443746 complement(3320026..3321288) 1 NC_022657.1 COG0642 Signal transduction histidine kinase; sensory histidine kinase 3321288 17443746 AFR_15425 Actinoplanes friuliensis DSM 7358 sensory histidine kinase YP_008734420.1 3320026 R 1246995 CDS YP_008734421.1 556565996 17443747 complement(3321281..3321958) 1 NC_022657.1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; chemotaxis protein CheY 3321958 17443747 AFR_15430 Actinoplanes friuliensis DSM 7358 chemotaxis protein CheY YP_008734421.1 3321281 R 1246995 CDS YP_008734422.1 556565997 17443748 3322034..3322327 1 NC_022657.1 COG1359 Uncharacterized conserved protein; antibiotic biosynthesis monooxygenase 3322327 17443748 AFR_15435 Actinoplanes friuliensis DSM 7358 antibiotic biosynthesis monooxygenase YP_008734422.1 3322034 D 1246995 CDS YP_008734423.1 556565998 17443749 complement(3322328..3323584) 1 NC_022657.1 COG4099 Predicted peptidase; hypothetical protein 3323584 17443749 AFR_15440 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734423.1 3322328 R 1246995 CDS YP_008734424.1 556565999 17443750 complement(3323710..3324798) 1 NC_022657.1 COG4188 Predicted dienelactone hydrolase; lipase 3324798 17443750 AFR_15445 Actinoplanes friuliensis DSM 7358 lipase YP_008734424.1 3323710 R 1246995 CDS YP_008734425.1 556566000 17443751 complement(3324889..3325761) 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); short-chain dehydrogenase 3325761 17443751 AFR_15450 Actinoplanes friuliensis DSM 7358 short-chain dehydrogenase YP_008734425.1 3324889 R 1246995 CDS YP_008734426.1 556566001 17443752 complement(3325761..3326492) 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); 3-ketoacyl-ACP reductase 3326492 17443752 AFR_15455 Actinoplanes friuliensis DSM 7358 3-ketoacyl-ACP reductase YP_008734426.1 3325761 R 1246995 CDS YP_008734427.1 556566002 17443753 complement(3326548..3327378) 1 NC_022657.1 COG2207 AraC-type DNA-binding domain-containing proteins; AraC family transcriptional regulator 3327378 17443753 AFR_15460 Actinoplanes friuliensis DSM 7358 AraC family transcriptional regulator YP_008734427.1 3326548 R 1246995 CDS YP_008734428.1 556566003 17443754 3327465..3329087 1 NC_022657.1 COG0840 Methyl-accepting chemotaxis protein; putative methyl-accepting chemotaxis protein 3329087 17443754 AFR_15465 Actinoplanes friuliensis DSM 7358 putative methyl-accepting chemotaxis protein YP_008734428.1 3327465 D 1246995 CDS YP_008734429.1 556566004 17443755 3329157..3329762 1 NC_022657.1 COG1309 Transcriptional regulator; TetR family transcriptional regulator 3329762 17443755 AFR_15470 Actinoplanes friuliensis DSM 7358 TetR family transcriptional regulator YP_008734429.1 3329157 D 1246995 CDS YP_008734430.1 556566005 17443756 3329782..3330405 1 NC_022657.1 hypothetical protein 3330405 17443756 AFR_15475 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734430.1 3329782 D 1246995 CDS YP_008734431.1 556566006 17443757 complement(3330408..3331511) 1 NC_022657.1 COG2755 Lysophospholipase L1 and related esterases; Polypeptide N-acetylgalactosaminyltransferase 13 3331511 17443757 AFR_15480 Actinoplanes friuliensis DSM 7358 Polypeptide N-acetylgalactosaminyltransferase 13 YP_008734431.1 3330408 R 1246995 CDS YP_008734432.1 556566007 17443758 complement(3331568..3334807) 1 NC_022657.1 COG3537 Putative alpha-1,2-mannosidase; alpha-1,2-mannosidase 3334807 17443758 AFR_15485 Actinoplanes friuliensis DSM 7358 alpha-1,2-mannosidase YP_008734432.1 3331568 R 1246995 CDS YP_008734433.1 556566008 17443759 3335015..3337888 1 NC_022657.1 COG3537 Putative alpha-1,2-mannosidase; alpha-1,2-mannosidase 3337888 17443759 AFR_15490 Actinoplanes friuliensis DSM 7358 alpha-1,2-mannosidase YP_008734433.1 3335015 D 1246995 CDS YP_008734434.1 556566009 17443760 3338021..3339076 1 NC_022657.1 COG1876 D-alanyl-D-alanine carboxypeptidase; Extracellular matrix-binding protein ebhB 3339076 17443760 AFR_15495 Actinoplanes friuliensis DSM 7358 Extracellular matrix-binding protein ebhB YP_008734434.1 3338021 D 1246995 CDS YP_008734435.1 556566010 17443761 complement(3339083..3339460) 1 NC_022657.1 hypothetical protein 3339460 17443761 AFR_15500 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734435.1 3339083 R 1246995 CDS YP_008734436.1 556566011 17443762 3339503..3340207 1 NC_022657.1 hypothetical protein 3340207 17443762 AFR_15505 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734436.1 3339503 D 1246995 CDS YP_008734437.1 556566012 17443763 complement(3340424..3341362) 1 NC_022657.1 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases; luciferase family protein 3341362 17443763 AFR_15510 Actinoplanes friuliensis DSM 7358 luciferase family protein YP_008734437.1 3340424 R 1246995 CDS YP_008734438.1 556566013 17443764 3341439..3342035 1 NC_022657.1 COG1309 Transcriptional regulator; TetR family transcriptional regulator 3342035 17443764 AFR_15515 Actinoplanes friuliensis DSM 7358 TetR family transcriptional regulator YP_008734438.1 3341439 D 1246995 CDS YP_008734439.1 556566014 17443765 complement(3342058..3342255) 1 NC_022657.1 hypothetical protein 3342255 17443765 AFR_15520 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734439.1 3342058 R 1246995 CDS YP_008734440.1 556566015 17443766 3342446..3346357 1 NC_022657.1 COG1020 Non-ribosomal peptide synthetase modules and related proteins; hypothetical protein 3346357 17443766 AFR_15525 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734440.1 3342446 D 1246995 CDS YP_008734441.1 556566016 17443767 3346354..3347679 1 NC_022657.1 COG0308 Aminopeptidase N; peptidase M1, membrane alanine aminopeptidase 3347679 17443767 AFR_15530 Actinoplanes friuliensis DSM 7358 peptidase M1, membrane alanine aminopeptidase YP_008734441.1 3346354 D 1246995 CDS YP_008734442.1 556566017 17443768 3347843..3350803 1 NC_022657.1 COG2133 Glucose/sorbosone dehydrogenases; large, multifunctional secreted protein 3350803 17443768 AFR_15535 Actinoplanes friuliensis DSM 7358 large, multifunctional secreted protein YP_008734442.1 3347843 D 1246995 CDS YP_008734443.1 556566018 17443769 complement(3350847..3351908) 1 NC_022657.1 COG1533 DNA repair photolyase; Spore photoproduct lyase 3351908 17443769 AFR_15540 Actinoplanes friuliensis DSM 7358 Spore photoproduct lyase YP_008734443.1 3350847 R 1246995 CDS YP_008734444.1 556566019 17443770 complement(3351905..3352318) 1 NC_022657.1 COG1846 Transcriptional regulators; putative HTH-type transcriptional regulator 3352318 17443770 AFR_15545 Actinoplanes friuliensis DSM 7358 putative HTH-type transcriptional regulator YP_008734444.1 3351905 R 1246995 CDS YP_008734445.1 556566020 17443771 3352372..3353133 1 NC_022657.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); alpha/beta hydrolase 3353133 17443771 AFR_15550 Actinoplanes friuliensis DSM 7358 alpha/beta hydrolase YP_008734445.1 3352372 D 1246995 CDS YP_008734446.1 556566021 17443772 complement(3353130..3354008) 1 NC_022657.1 nitroreductase 3354008 17443772 AFR_15555 Actinoplanes friuliensis DSM 7358 nitroreductase YP_008734446.1 3353130 R 1246995 CDS YP_008734447.1 556566022 17443773 complement(3354005..3355060) 1 NC_022657.1 COG1073 Hydrolases of the alpha/beta superfamily; hypothetical protein 3355060 17443773 AFR_15560 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734447.1 3354005 R 1246995 CDS YP_008734448.1 556566023 17443774 complement(3355057..3355503) 1 NC_022657.1 hypothetical protein 3355503 17443774 AFR_15565 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734448.1 3355057 R 1246995 CDS YP_008734449.1 556566024 17443775 complement(3355500..3357029) 1 NC_022657.1 COG1541 Coenzyme F390 synthetase; coenzyme F390 synthetase 3357029 17443775 AFR_15570 Actinoplanes friuliensis DSM 7358 coenzyme F390 synthetase YP_008734449.1 3355500 R 1246995 CDS YP_008734450.1 556566025 17443776 3357310..3358068 1 NC_022657.1 COG0456 Acetyltransferases; GCN5-related N-acetyltransferase 3358068 17443776 AFR_15575 Actinoplanes friuliensis DSM 7358 GCN5-related N-acetyltransferase YP_008734450.1 3357310 D 1246995 CDS YP_008734451.1 556566026 17443777 3358183..3358389 1 NC_022657.1 hypothetical protein 3358389 17443777 AFR_15580 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734451.1 3358183 D 1246995 CDS YP_008734452.1 556566027 17443778 complement(3358410..3358808) 1 NC_022657.1 hypothetical protein 3358808 17443778 AFR_15585 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734452.1 3358410 R 1246995 CDS YP_008734453.1 556566028 17443779 complement(3358954..3360408) 1 NC_022657.1 COG3507 Beta-xylosidase; glycoside hydrolase 3360408 17443779 AFR_15590 Actinoplanes friuliensis DSM 7358 glycoside hydrolase YP_008734453.1 3358954 R 1246995 CDS YP_008734454.1 556566029 17443780 3360625..3361779 1 NC_022657.1 hypothetical protein 3361779 17443780 AFR_15595 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734454.1 3360625 D 1246995 CDS YP_008734455.1 556566030 17443781 complement(3361784..3362650) 1 NC_022657.1 COG2207 AraC-type DNA-binding domain-containing proteins; AraC family transcriptional regulator 3362650 17443781 AFR_15600 Actinoplanes friuliensis DSM 7358 AraC family transcriptional regulator YP_008734455.1 3361784 R 1246995 CDS YP_008734456.1 556566031 17443782 complement(3362728..3363588) 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); putative short-chain dehydrogenase 3363588 17443782 AFR_15605 Actinoplanes friuliensis DSM 7358 putative short-chain dehydrogenase YP_008734456.1 3362728 R 1246995 CDS YP_008734457.1 556566032 17443783 3363669..3364289 1 NC_022657.1 COG1309 Transcriptional regulator; putative TetR-family transcriptional regulator 3364289 17443783 AFR_15610 Actinoplanes friuliensis DSM 7358 putative TetR-family transcriptional regulator YP_008734457.1 3363669 D 1246995 CDS YP_008734458.1 556566033 17443784 3364573..3365517 1 NC_022657.1 COG2132 Putative multicopper oxidases; putative multicopper oxidase 3365517 17443784 AFR_15615 Actinoplanes friuliensis DSM 7358 putative multicopper oxidase YP_008734458.1 3364573 D 1246995 CDS YP_008734459.1 556566034 17443785 3365578..3369450 1 NC_022657.1 COG2133 Glucose/sorbosone dehydrogenases; hypothetical protein 3369450 17443785 AFR_15620 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734459.1 3365578 D 1246995 CDS YP_008734460.1 556566035 17443786 3369447..3370943 1 NC_022657.1 copper binding protein, plastocyanin/azurin family 3370943 17443786 AFR_15625 Actinoplanes friuliensis DSM 7358 copper binding protein, plastocyanin/azurin family YP_008734460.1 3369447 D 1246995 CDS YP_008734461.1 556566036 17443787 3370940..3371920 1 NC_022657.1 hypothetical protein 3371920 17443787 AFR_15630 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734461.1 3370940 D 1246995 CDS YP_008734462.1 556566037 17443788 3372061..3372699 1 NC_022657.1 COG0500 SAM-dependent methyltransferases; ubiquinone/menaquinone biosynthesis methyltransferase ubiE 3372699 17443788 AFR_15635 Actinoplanes friuliensis DSM 7358 ubiquinone/menaquinone biosynthesis methyltransferase ubiE YP_008734462.1 3372061 D 1246995 CDS YP_008734463.1 556566038 17443789 3372699..3373361 1 NC_022657.1 hypothetical protein 3373361 17443789 AFR_15640 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734463.1 3372699 D 1246995 CDS YP_008734464.1 556566039 17443790 3373415..3374146 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); oxidoreductase 3374146 17443790 AFR_15645 Actinoplanes friuliensis DSM 7358 oxidoreductase YP_008734464.1 3373415 D 1246995 CDS YP_008734465.1 556566040 17443791 complement(3374131..3374892) 1 NC_022657.1 COG0599 Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit; carboxymuconolactone decarboxylase 3374892 17443791 AFR_15650 Actinoplanes friuliensis DSM 7358 carboxymuconolactone decarboxylase YP_008734465.1 3374131 R 1246995 CDS YP_008734466.1 556566041 17443792 complement(3374889..3375758) 1 NC_022657.1 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases; 3-hydroxyisobutyrate dehydrogenase 3375758 17443792 AFR_15655 Actinoplanes friuliensis DSM 7358 3-hydroxyisobutyrate dehydrogenase YP_008734466.1 3374889 R 1246995 CDS YP_008734467.1 556566042 17443793 complement(3375751..3376116) 1 NC_022657.1 COG1917 Uncharacterized conserved protein, contains double-stranded beta-helix domain; hypothetical protein 3376116 17443793 AFR_15660 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734467.1 3375751 R 1246995 CDS YP_008734468.1 556566043 17443794 complement(3376113..3377012) 1 NC_022657.1 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases; 6-phosphogluconate dehydrogenase, NAD-binding protein 3377012 17443794 AFR_15665 Actinoplanes friuliensis DSM 7358 6-phosphogluconate dehydrogenase, NAD-binding protein YP_008734468.1 3376113 R 1246995 CDS YP_008734469.1 556566044 17443795 complement(3377012..3377815) 1 NC_022657.1 COG0491 Zn-dependent hydrolases, including glyoxylases; beta-lactamase domain-containing protein 3377815 17443795 AFR_15670 Actinoplanes friuliensis DSM 7358 beta-lactamase domain-containing protein YP_008734469.1 3377012 R 1246995 CDS YP_008734470.1 556566045 17443796 complement(3377812..3378753) 1 NC_022657.1 hypothetical protein 3378753 17443796 AFR_15675 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734470.1 3377812 R 1246995 CDS YP_008734471.1 556566046 17443797 complement(3378770..3379861) 1 NC_022657.1 COG3842 ABC-type spermidine/putrescine transport systems, ATPase components; spermidine/putrescine ABC transporter ATPase 3379861 17443797 AFR_15680 Actinoplanes friuliensis DSM 7358 spermidine/putrescine ABC transporter ATPase YP_008734471.1 3378770 R 1246995 CDS YP_008734472.1 556566047 17443798 complement(3379858..3381573) 1 NC_022657.1 COG1176 ABC-type spermidine/putrescine transport system, permease component I; binding-protein-dependent transport systems inner membrane component 3381573 17443798 AFR_15685 Actinoplanes friuliensis DSM 7358 binding-protein-dependent transport systems inner membrane component YP_008734472.1 3379858 R 1246995 CDS YP_008734473.1 556566048 17443799 complement(3381576..3382631) 1 NC_022657.1 COG0687 Spermidine/putrescine-binding periplasmic protein; extracellular solute-binding protein 3382631 17443799 AFR_15690 Actinoplanes friuliensis DSM 7358 extracellular solute-binding protein YP_008734473.1 3381576 R 1246995 CDS YP_008734474.1 556566049 17443800 complement(3382752..3383537) 1 NC_022657.1 COG1414 Transcriptional regulator; IclR family transcriptional regulator 3383537 17443800 AFR_15695 Actinoplanes friuliensis DSM 7358 IclR family transcriptional regulator YP_008734474.1 3382752 R 1246995 CDS YP_008734475.1 556566050 17443801 3383753..3384580 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); short-chain dehydrogenase/reductase SDR 3384580 17443801 AFR_15700 Actinoplanes friuliensis DSM 7358 short-chain dehydrogenase/reductase SDR YP_008734475.1 3383753 D 1246995 CDS YP_008734476.1 556566051 17443802 complement(3384581..3386260) 1 NC_022657.1 COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]; putative acetolactate synthase large subunit 3386260 17443802 AFR_15705 Actinoplanes friuliensis DSM 7358 putative acetolactate synthase large subunit YP_008734476.1 3384581 R 1246995 CDS YP_008734477.1 556566052 17443803 complement(3386257..3386724) 1 NC_022657.1 COG0599 Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit; 4-carboxymuconolactone decarboxylase 3386724 17443803 AFR_15710 Actinoplanes friuliensis DSM 7358 4-carboxymuconolactone decarboxylase YP_008734477.1 3386257 R 1246995 CDS YP_008734478.1 556566053 17443804 complement(3386771..3387424) 1 NC_022657.1 COG1802 Transcriptional regulators; GntR family transcriptional regulator 3387424 17443804 AFR_15715 Actinoplanes friuliensis DSM 7358 GntR family transcriptional regulator YP_008734478.1 3386771 R 1246995 CDS YP_008734479.1 556566054 17443805 3387576..3388367 1 NC_022657.1 COG3836 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase; 2-dehydro-3-deoxyglucarate aldolase 3388367 17443805 AFR_15720 Actinoplanes friuliensis DSM 7358 2-dehydro-3-deoxyglucarate aldolase YP_008734479.1 3387576 D 1246995 CDS YP_008734480.1 556566055 17443806 3388357..3389268 1 NC_022657.1 hypothetical protein 3389268 17443806 AFR_15725 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734480.1 3388357 D 1246995 CDS YP_008734481.1 556566056 17443807 3389265..3390728 1 NC_022657.1 COG2072 Predicted flavoprotein involved in K+ transport; 4-hydroxyacetophenone monooxygenase HapE 3390728 17443807 AFR_15730 Actinoplanes friuliensis DSM 7358 4-hydroxyacetophenone monooxygenase HapE YP_008734481.1 3389265 D 1246995 CDS YP_008734482.1 556566057 17443808 complement(3390712..3391557) 1 NC_022657.1 COG0491 Zn-dependent hydrolases, including glyoxylases; hypothetical protein 3391557 17443808 AFR_15735 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734482.1 3390712 R 1246995 CDS YP_008734483.1 556566058 17443809 complement(3391554..3392117) 1 NC_022657.1 hypothetical protein 3392117 17443809 AFR_15740 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734483.1 3391554 R 1246995 CDS YP_008734484.1 556566059 17443810 complement(3392114..3393037) 1 NC_022657.1 COG0516 IMP dehydrogenase/GMP reductase; hypothetical protein 3393037 17443810 AFR_15745 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734484.1 3392114 R 1246995 CDS YP_008734485.1 556566060 17443811 3393076..3393828 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); short-chain dehydrogenase/reductase SDR 3393828 17443811 AFR_15750 Actinoplanes friuliensis DSM 7358 short-chain dehydrogenase/reductase SDR YP_008734485.1 3393076 D 1246995 CDS YP_008734486.1 556566061 17443812 3393845..3395272 1 NC_022657.1 COG1012 NAD-dependent aldehyde dehydrogenases; aldehyde dehydrogenase 3395272 17443812 AFR_15755 Actinoplanes friuliensis DSM 7358 aldehyde dehydrogenase YP_008734486.1 3393845 D 1246995 CDS YP_008734487.1 556566062 17443813 complement(3395283..3396224) 1 NC_022657.1 COG3173 Predicted aminoglycoside phosphotransferase; hypothetical protein 3396224 17443813 AFR_15760 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734487.1 3395283 R 1246995 CDS YP_008734488.1 556566063 17443814 complement(3396242..3397423) 1 NC_022657.1 COG0477 Permeases of the major facilitator superfamily; Bcr/CflA subfamily drug resistance transporter 3397423 17443814 AFR_15765 Actinoplanes friuliensis DSM 7358 Bcr/CflA subfamily drug resistance transporter YP_008734488.1 3396242 R 1246995 CDS YP_008734489.1 556566064 17443815 3397507..3398070 1 NC_022657.1 COG5516 Conserved protein containing a Zn-ribbon-like motif, possibly RNA-binding; putative RNA-binding protein containing a Zn-ribbon-like motif 3398070 17443815 AFR_15770 Actinoplanes friuliensis DSM 7358 putative RNA-binding protein containing a Zn-ribbon-like motif YP_008734489.1 3397507 D 1246995 CDS YP_008734490.1 556566065 17443816 complement(3398018..3398926) 1 NC_022657.1 COG0583 Transcriptional regulator; transcriptional regulator 3398926 17443816 AFR_15775 Actinoplanes friuliensis DSM 7358 transcriptional regulator YP_008734490.1 3398018 R 1246995 CDS YP_008734491.1 556566066 17443817 3398995..3399519 1 NC_022657.1 hypothetical protein 3399519 17443817 AFR_15780 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734491.1 3398995 D 1246995 CDS YP_008734492.1 556566067 17443818 complement(3399497..3400510) 1 NC_022657.1 hypothetical protein 3400510 17443818 AFR_15785 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734492.1 3399497 R 1246995 CDS YP_008734493.1 556566068 17443819 3400558..3401154 1 NC_022657.1 COG0500 SAM-dependent methyltransferases; ubiquinone/menaquinone biosynthesis methyltransferase ubiE 3401154 17443819 AFR_15790 Actinoplanes friuliensis DSM 7358 ubiquinone/menaquinone biosynthesis methyltransferase ubiE YP_008734493.1 3400558 D 1246995 CDS YP_008734494.1 556566069 17443820 3401317..3402849 1 NC_022657.1 COG3866 Pectate lyase; Pectate lyase/Amb allergen 3402849 17443820 AFR_15795 Actinoplanes friuliensis DSM 7358 Pectate lyase/Amb allergen YP_008734494.1 3401317 D 1246995 CDS YP_008734495.1 556566070 17443821 3402913..3403782 1 NC_022657.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); hypothetical protein 3403782 17443821 AFR_15800 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734495.1 3402913 D 1246995 CDS YP_008734496.1 556566071 17443822 3403875..3405023 1 NC_022657.1 COG2356 Endonuclease I; endonuclease i 3405023 17443822 AFR_15805 Actinoplanes friuliensis DSM 7358 endonuclease i YP_008734496.1 3403875 D 1246995 CDS YP_008734497.1 556566072 17443823 complement(3404990..3405880) 1 NC_022657.1 COG0010 Arginase/agmatinase/formimionoglutamate hydrolase, arginase family; arginase/agmatinase/formiminoglutamase 3405880 17443823 AFR_15810 Actinoplanes friuliensis DSM 7358 arginase/agmatinase/formiminoglutamase YP_008734497.1 3404990 R 1246995 CDS YP_008734498.1 556566073 17443824 complement(3405947..3409114) 1 NC_022657.1 hypothetical protein 3409114 17443824 AFR_15815 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734498.1 3405947 R 1246995 CDS YP_008734499.1 556566074 17443825 3409411..3417162 1 NC_022657.1 COG3209 Rhs family protein; YD repeat-containing protein 3417162 17443825 AFR_15820 Actinoplanes friuliensis DSM 7358 YD repeat-containing protein YP_008734499.1 3409411 D 1246995 CDS YP_008734500.1 556566075 17443826 3417171..3417599 1 NC_022657.1 COG3209 Rhs family protein; hypothetical protein 3417599 17443826 AFR_15825 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734500.1 3417171 D 1246995 CDS YP_008734501.1 556566076 17443827 3417592..3418140 1 NC_022657.1 hypothetical protein 3418140 17443827 AFR_15830 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734501.1 3417592 D 1246995 CDS YP_008734502.1 556566077 17443828 3418161..3418442 1 NC_022657.1 hypothetical protein 3418442 17443828 AFR_15835 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734502.1 3418161 D 1246995 CDS YP_008734503.1 556566078 17443829 complement(3418452..3418931) 1 NC_022657.1 COG0593 ATPase involved in DNA replication initiation; chromosomal replication initiator protein dnaa 3418931 17443829 AFR_15840 Actinoplanes friuliensis DSM 7358 chromosomal replication initiator protein dnaa YP_008734503.1 3418452 R 1246995 CDS YP_008734504.1 556566079 17443830 complement(3418945..3419949) 1 NC_022657.1 COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases); aldo/keto reductase 3419949 17443830 AFR_15845 Actinoplanes friuliensis DSM 7358 aldo/keto reductase YP_008734504.1 3418945 R 1246995 CDS YP_008734505.1 556566080 17443831 3420039..3420623 1 NC_022657.1 COG1309 Transcriptional regulator; TetR family transcriptional regulator 3420623 17443831 AFR_15850 Actinoplanes friuliensis DSM 7358 TetR family transcriptional regulator YP_008734505.1 3420039 D 1246995 CDS YP_008734506.1 556566081 17443832 3420737..3421786 1 NC_022657.1 COG3181 Uncharacterized protein conserved in bacteria; hypothetical protein 3421786 17443832 AFR_15855 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734506.1 3420737 D 1246995 CDS YP_008734507.1 556566082 17443833 3421820..3422311 1 NC_022657.1 hypothetical protein 3422311 17443833 AFR_15860 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734507.1 3421820 D 1246995 CDS YP_008734508.1 556566083 17443834 3422308..3423855 1 NC_022657.1 COG3333 Uncharacterized protein conserved in bacteria; hypothetical protein 3423855 17443834 AFR_15865 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734508.1 3422308 D 1246995 CDS YP_008734509.1 556566084 17443835 complement(3423896..3424834) 1 NC_022657.1 COG3181 Uncharacterized protein conserved in bacteria; putative tricarboxylic transport membrane protein 3424834 17443835 AFR_15870 Actinoplanes friuliensis DSM 7358 putative tricarboxylic transport membrane protein YP_008734509.1 3423896 R 1246995 CDS YP_008734510.1 556566085 17443836 3424950..3426509 1 NC_022657.1 COG3290 Signal transduction histidine kinase regulating citrate/malate metabolism; two component system histidine kinase 3426509 17443836 AFR_15875 Actinoplanes friuliensis DSM 7358 two component system histidine kinase YP_008734510.1 3424950 D 1246995 CDS YP_008734511.1 556566086 17443837 3426506..3427174 1 NC_022657.1 COG4565 Response regulator of citrate/malate metabolism; response regulator of citrate/malate metabolism 3427174 17443837 AFR_15880 Actinoplanes friuliensis DSM 7358 response regulator of citrate/malate metabolism YP_008734511.1 3426506 D 1246995 CDS YP_008734512.1 556566087 17443838 complement(3427206..3429512) 1 NC_022657.1 COG0457 FOG: TPR repeat; TPR repeat-containing protein 3429512 17443838 AFR_15885 Actinoplanes friuliensis DSM 7358 TPR repeat-containing protein YP_008734512.1 3427206 R 1246995 CDS YP_008734513.1 556566088 17443839 complement(3429690..3430298) 1 NC_022657.1 COG0110 Acetyltransferase (isoleucine patch superfamily); Acyl-[acyl-carrier-protein]-UDP-N- acetylglucosamine O-acyltransferase 3430298 17443839 AFR_15890 Actinoplanes friuliensis DSM 7358 Acyl-[acyl-carrier-protein]-UDP-N- acetylglucosamine O-acyltransferase YP_008734513.1 3429690 R 1246995 CDS YP_008734514.1 556566089 17443840 3430614..3431687 1 NC_022657.1 COG0673 Predicted dehydrogenases and related proteins; Inositol 2-dehydrogenase 3431687 17443840 AFR_15895 Actinoplanes friuliensis DSM 7358 Inositol 2-dehydrogenase YP_008734514.1 3430614 D 1246995 CDS YP_008734515.1 556566090 17443841 3431684..3432649 1 NC_022657.1 COG0451 Nucleoside-diphosphate-sugar epimerases; NAD-dependent epimerase/dehydratase 3432649 17443841 AFR_15900 Actinoplanes friuliensis DSM 7358 NAD-dependent epimerase/dehydratase YP_008734515.1 3431684 D 1246995 CDS YP_008734516.1 556566091 17443842 3432628..3433785 1 NC_022657.1 COG0399 Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; DegT/DnrJ/EryC1/StrS aminotransferase 3433785 17443842 AFR_15905 Actinoplanes friuliensis DSM 7358 DegT/DnrJ/EryC1/StrS aminotransferase YP_008734516.1 3432628 D 1246995 CDS YP_008734517.1 556566092 17443843 3433782..3434438 1 NC_022657.1 COG0110 Acetyltransferase (isoleucine patch superfamily); acetyltransferase 3434438 17443843 AFR_15910 Actinoplanes friuliensis DSM 7358 acetyltransferase YP_008734517.1 3433782 D 1246995 CDS YP_008734518.1 556566093 17443844 3434440..3435540 1 NC_022657.1 COG0399 Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; DegT/DnrJ/EryC1/StrS aminotransferase 3435540 17443844 AFR_15915 Actinoplanes friuliensis DSM 7358 DegT/DnrJ/EryC1/StrS aminotransferase YP_008734518.1 3434440 D 1246995 CDS YP_008734519.1 556566094 17443845 3435665..3436912 1 NC_022657.1 COG0477 Permeases of the major facilitator superfamily; putative MFS-type transporter 3436912 17443845 AFR_15920 Actinoplanes friuliensis DSM 7358 putative MFS-type transporter YP_008734519.1 3435665 D 1246995 CDS YP_008734520.1 556566095 17443846 3436909..3437958 1 NC_022657.1 COG0823 Periplasmic component of the Tol biopolymer transport system; protein tolB 3437958 17443846 AFR_15925 Actinoplanes friuliensis DSM 7358 protein tolB YP_008734520.1 3436909 D 1246995 CDS YP_008734521.1 556566096 17443847 complement(3438588..3442340) 1 NC_022657.1 hypothetical protein 3442340 17443847 AFR_15930 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734521.1 3438588 R 1246995 CDS YP_008734522.1 556566097 17443848 complement(3442589..3442876) 1 NC_022657.1 COG0236 Acyl carrier protein; hypothetical protein 3442876 17443848 AFR_15935 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734522.1 3442589 R 1246995 CDS YP_008734523.1 556566098 17443849 complement(3442873..3444099) 1 NC_022657.1 COG0019 Diaminopimelate decarboxylase; pyridoxal-dependent decarboxylase exosortase system type 1 protein 3444099 17443849 AFR_15940 Actinoplanes friuliensis DSM 7358 pyridoxal-dependent decarboxylase exosortase system type 1 protein YP_008734523.1 3442873 R 1246995 CDS YP_008734524.1 556566099 17443850 complement(3444096..3445661) 1 NC_022657.1 COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II; acetyl-coenzyme A synthetase 3445661 17443850 AFR_15945 Actinoplanes friuliensis DSM 7358 acetyl-coenzyme A synthetase YP_008734524.1 3444096 R 1246995 CDS YP_008734525.1 556566100 17443851 complement(3445711..3446571) 1 NC_022657.1 hypothetical protein 3446571 17443851 AFR_15950 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734525.1 3445711 R 1246995 CDS YP_008734526.1 556566101 17443852 complement(3447124..3447342) 1 NC_022657.1 hypothetical protein 3447342 17443852 AFR_15955 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734526.1 3447124 R 1246995 CDS YP_008734527.1 556566102 17443853 3447305..3448126 1 NC_022657.1 hypothetical protein 3448126 17443853 AFR_15960 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734527.1 3447305 D 1246995 CDS YP_008734528.1 556566103 17443854 complement(3448211..3449041) 1 NC_022657.1 COG0842 ABC-type multidrug transport system, permease component; ABC-2 type transporter 3449041 17443854 AFR_15965 Actinoplanes friuliensis DSM 7358 ABC-2 type transporter YP_008734528.1 3448211 R 1246995 CDS YP_008734529.1 556566104 17443855 complement(3449038..3450066) 1 NC_022657.1 COG1131 ABC-type multidrug transport system, ATPase component; ABC transporter-like protein 3450066 17443855 AFR_15970 Actinoplanes friuliensis DSM 7358 ABC transporter-like protein YP_008734529.1 3449038 R 1246995 CDS YP_008734530.1 556566105 17443856 complement(3450063..3451109) 1 NC_022657.1 COG0463 Glycosyltransferases involved in cell wall biogenesis; glycosyl transferase family protein 3451109 17443856 AFR_15975 Actinoplanes friuliensis DSM 7358 glycosyl transferase family protein YP_008734530.1 3450063 R 1246995 CDS YP_008734531.1 556566106 17443857 3451633..3452697 1 NC_022657.1 COG0438 Glycosyltransferase; glycosyltransferase 3452697 17443857 AFR_15980 Actinoplanes friuliensis DSM 7358 glycosyltransferase YP_008734531.1 3451633 D 1246995 CDS YP_008734532.1 556566107 17443858 complement(3452708..3454072) 1 NC_022657.1 hypothetical protein 3454072 17443858 AFR_15985 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734532.1 3452708 R 1246995 CDS YP_008734533.1 556566108 17443859 complement(3454084..3455052) 1 NC_022657.1 hypothetical protein 3455052 17443859 AFR_15990 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734533.1 3454084 R 1246995 CDS YP_008734534.1 556566109 17443860 3455469..3456749 1 NC_022657.1 COG0438 Glycosyltransferase; Glycogen synthase 3456749 17443860 AFR_15995 Actinoplanes friuliensis DSM 7358 Glycogen synthase YP_008734534.1 3455469 D 1246995 CDS YP_008734535.1 556566110 17443861 3456746..3457612 1 NC_022657.1 COG1215 Glycosyltransferases, probably involved in cell wall biogenesis; glycosyl transferase family protein 3457612 17443861 AFR_16000 Actinoplanes friuliensis DSM 7358 glycosyl transferase family protein YP_008734535.1 3456746 D 1246995 CDS YP_008734536.1 556566111 17443862 3457619..3458284 1 NC_022657.1 COG0726 Predicted xylanase/chitin deacetylase; polysaccharide deacetylase 3458284 17443862 AFR_16005 Actinoplanes friuliensis DSM 7358 polysaccharide deacetylase YP_008734536.1 3457619 D 1246995 CDS YP_008734537.1 556566112 17443863 complement(3458281..3459213) 1 NC_022657.1 COG1216 Predicted glycosyltransferases; Polypeptide N-acetylgalactosaminyltransferase 5 3459213 17443863 AFR_16010 Actinoplanes friuliensis DSM 7358 Polypeptide N-acetylgalactosaminyltransferase 5 YP_008734537.1 3458281 R 1246995 CDS YP_008734538.1 556566113 17443864 complement(3459306..3460619) 1 NC_022657.1 COG1004 Predicted UDP-glucose 6-dehydrogenase; UDPglucose 6-dehydrogenase 3460619 17443864 AFR_16015 Actinoplanes friuliensis DSM 7358 UDPglucose 6-dehydrogenase YP_008734538.1 3459306 R 1246995 CDS YP_008734539.1 556566114 17443865 complement(3460619..3461977) 1 NC_022657.1 COG2148 Sugar transferases involved in lipopolysaccharide synthesis; undecaprenyl-phosphate galactose phosphotransferase 3461977 17443865 AFR_16020 Actinoplanes friuliensis DSM 7358 undecaprenyl-phosphate galactose phosphotransferase YP_008734539.1 3460619 R 1246995 CDS YP_008734540.1 556566115 17443866 complement(3462436..3463065) 1 NC_022657.1 COG1898 dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes; dTDP-4-dehydrorhamnose 3,5-epimerase 3463065 17443866 AFR_16025 Actinoplanes friuliensis DSM 7358 dTDP-4-dehydrorhamnose 3,5-epimerase YP_008734540.1 3462436 R 1246995 CDS YP_008734541.1 556566116 17443867 complement(3463062..3463949) 1 NC_022657.1 COG1209 dTDP-glucose pyrophosphorylase; putative glucose-1-phosphate thymidyltransferase 3463949 17443867 AFR_16030 Actinoplanes friuliensis DSM 7358 putative glucose-1-phosphate thymidyltransferase YP_008734541.1 3463062 R 1246995 CDS YP_008734542.1 556566117 17443868 3463993..3464967 1 NC_022657.1 COG1088 dTDP-D-glucose 4,6-dehydratase; putative dTDP-glucose-4,6-dehydratase 3464967 17443868 AFR_16035 Actinoplanes friuliensis DSM 7358 putative dTDP-glucose-4,6-dehydratase YP_008734542.1 3463993 D 1246995 CDS YP_008734543.1 556566118 17443869 3464937..3465809 1 NC_022657.1 COG1091 dTDP-4-dehydrorhamnose reductase; dTDP-4-dehydrorhamnose reductase 3465809 17443869 AFR_16040 Actinoplanes friuliensis DSM 7358 dTDP-4-dehydrorhamnose reductase YP_008734543.1 3464937 D 1246995 CDS YP_008734544.1 556566119 17443870 complement(3465812..3466783) 1 NC_022657.1 COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases; zinc-binding alcohol dehydrogenase 3466783 17443870 AFR_16045 Actinoplanes friuliensis DSM 7358 zinc-binding alcohol dehydrogenase YP_008734544.1 3465812 R 1246995 CDS YP_008734545.1 556566120 17443871 complement(3466863..3467540) 1 NC_022657.1 hypothetical protein 3467540 17443871 AFR_16050 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734545.1 3466863 R 1246995 CDS YP_008734546.1 556566121 17443872 3467689..3468573 1 NC_022657.1 sulfotransferase 3468573 17443872 AFR_16055 Actinoplanes friuliensis DSM 7358 sulfotransferase YP_008734546.1 3467689 D 1246995 CDS YP_008734547.1 556566122 17443873 complement(3468581..3470431) 1 NC_022657.1 COG1082 Sugar phosphate isomerases/epimerases; putative sugar phosphate isomerase/epimerase 3470431 17443873 AFR_16060 Actinoplanes friuliensis DSM 7358 putative sugar phosphate isomerase/epimerase YP_008734547.1 3468581 R 1246995 CDS YP_008734548.1 556566123 17443874 complement(3470443..3471093) 1 NC_022657.1 COG1309 Transcriptional regulator; putative TetR-family transcriptional regulator 3471093 17443874 AFR_16065 Actinoplanes friuliensis DSM 7358 putative TetR-family transcriptional regulator YP_008734548.1 3470443 R 1246995 CDS YP_008734549.1 556566124 17443875 3471231..3472079 1 NC_022657.1 COG0169 Shikimate 5-dehydrogenase; shikimate 5-dehydrogenase 3472079 17443875 AFR_16070 Actinoplanes friuliensis DSM 7358 shikimate 5-dehydrogenase YP_008734549.1 3471231 D 1246995 CDS YP_008734550.1 556566125 17443876 3472111..3473514 1 NC_022657.1 hypothetical protein 3473514 17443876 AFR_16075 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734550.1 3472111 D 1246995 CDS YP_008734551.1 556566126 17443877 complement(3474508..3475743) 1 NC_022657.1 COG0477 Permeases of the major facilitator superfamily; mfs transporter 3475743 17443877 AFR_16080 Actinoplanes friuliensis DSM 7358 mfs transporter YP_008734551.1 3474508 R 1246995 CDS YP_008734552.1 556566127 17443878 3475846..3476802 1 NC_022657.1 COG0583 Transcriptional regulator; LysR family transcriptional regulator 3476802 17443878 AFR_16085 Actinoplanes friuliensis DSM 7358 LysR family transcriptional regulator YP_008734552.1 3475846 D 1246995 CDS YP_008734553.1 556566128 17443879 complement(3476854..3477036) 1 NC_022657.1 hypothetical protein 3477036 17443879 AFR_16090 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734553.1 3476854 R 1246995 CDS YP_008734554.1 556566129 17443880 3477147..3477491 1 NC_022657.1 COG0640 Predicted transcriptional regulators; ArsR family transcriptional regulator 3477491 17443880 AFR_16095 Actinoplanes friuliensis DSM 7358 ArsR family transcriptional regulator YP_008734554.1 3477147 D 1246995 CDS YP_008734555.1 556566130 17443881 3477591..3477956 1 NC_022657.1 COG3832 Uncharacterized conserved protein; Activator of Hsp90 ATPase 1 family protein 3477956 17443881 AFR_16100 Actinoplanes friuliensis DSM 7358 Activator of Hsp90 ATPase 1 family protein YP_008734555.1 3477591 D 1246995 CDS YP_008734556.1 556566131 17443882 3477943..3478512 1 NC_022657.1 hypothetical protein 3478512 17443882 AFR_16105 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734556.1 3477943 D 1246995 CDS YP_008734557.1 556566132 17443883 complement(3478509..3478991) 1 NC_022657.1 hypothetical protein 3478991 17443883 AFR_16110 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734557.1 3478509 R 1246995 CDS YP_008734558.1 556566133 17443884 complement(3479116..3480147) 1 NC_022657.1 COG0334 Glutamate dehydrogenase/leucine dehydrogenase; leucine dehydrogenase 3480147 17443884 AFR_16115 Actinoplanes friuliensis DSM 7358 leucine dehydrogenase YP_008734558.1 3479116 R 1246995 CDS YP_008734559.1 556566134 17443885 3480151..3480696 1 NC_022657.1 COG1522 Transcriptional regulators; AsnC family transcriptional regulator 3480696 17443885 AFR_16120 Actinoplanes friuliensis DSM 7358 AsnC family transcriptional regulator YP_008734559.1 3480151 D 1246995 CDS YP_008734560.1 556566135 17443886 complement(3480674..3481729) 1 NC_022657.1 hypothetical protein 3481729 17443886 AFR_16125 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734560.1 3480674 R 1246995 CDS YP_008734561.1 556566136 17443887 3481975..3482157 1 NC_022657.1 hypothetical protein 3482157 17443887 AFR_16130 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734561.1 3481975 D 1246995 CDS YP_008734562.1 556566137 17443888 3482215..3483594 1 NC_022657.1 COG1350 Predicted alternative tryptophan synthase beta-subunit (paralog of TrpB); tryptophan synthase subunit beta 3483594 17443888 AFR_16135 Actinoplanes friuliensis DSM 7358 tryptophan synthase subunit beta YP_008734562.1 3482215 D 1246995 CDS YP_008734563.1 556566138 17443889 3483691..3484371 1 NC_022657.1 hypothetical protein 3484371 17443889 AFR_16140 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734563.1 3483691 D 1246995 CDS YP_008734564.1 556566139 17443890 complement(3484355..3485014) 1 NC_022657.1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; response regulator receiver protein 3485014 17443890 AFR_16145 Actinoplanes friuliensis DSM 7358 response regulator receiver protein YP_008734564.1 3484355 R 1246995 CDS YP_008734565.1 556566140 17443891 complement(3485011..3486150) 1 NC_022657.1 COG4585 Signal transduction histidine kinase; histidine kinase 3486150 17443891 AFR_16150 Actinoplanes friuliensis DSM 7358 histidine kinase YP_008734565.1 3485011 R 1246995 CDS YP_008734566.1 556566141 17443892 3486358..3488481 1 NC_022657.1 COG2409 Predicted drug exporters of the RND superfamily; drug exporter of the RND superfamily-like protein 3488481 17443892 AFR_16155 Actinoplanes friuliensis DSM 7358 drug exporter of the RND superfamily-like protein YP_008734566.1 3486358 D 1246995 CDS YP_008734567.1 556566142 17443893 3488517..3489332 1 NC_022657.1 COG3324 Predicted enzyme related to lactoylglutathione lyase; glyoxalase/bleomycin resistance protein/dioxygenase 3489332 17443893 AFR_16160 Actinoplanes friuliensis DSM 7358 glyoxalase/bleomycin resistance protein/dioxygenase YP_008734567.1 3488517 D 1246995 CDS YP_008734568.1 556566143 17443894 3489441..3491180 1 NC_022657.1 COG0584 Glycerophosphoryl diester phosphodiesterase; glycerophosphoryl diester phosphodiesterase 3491180 17443894 AFR_16165 Actinoplanes friuliensis DSM 7358 glycerophosphoryl diester phosphodiesterase YP_008734568.1 3489441 D 1246995 CDS YP_008734569.1 556566144 17443895 complement(3491161..3492075) 1 NC_022657.1 hypothetical protein 3492075 17443895 AFR_16170 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734569.1 3491161 R 1246995 CDS YP_008734570.1 556566145 17443896 3492176..3492397 1 NC_022657.1 hypothetical protein 3492397 17443896 AFR_16175 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734570.1 3492176 D 1246995 CDS YP_008734571.1 556566146 17443897 complement(3492444..3494162) 1 NC_022657.1 COG0515 Serine/threonine protein kinase; serine/threonine protein kinase 3494162 17443897 AFR_16180 Actinoplanes friuliensis DSM 7358 serine/threonine protein kinase YP_008734571.1 3492444 R 1246995 CDS YP_008734572.1 556566147 17443898 complement(3494159..3494908) 1 NC_022657.1 hypothetical protein 3494908 17443898 AFR_16185 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734572.1 3494159 R 1246995 CDS YP_008734573.1 556566148 17443899 complement(3494918..3495115) 1 NC_022657.1 hypothetical protein 3495115 17443899 AFR_16190 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734573.1 3494918 R 1246995 CDS YP_008734574.1 556566149 17443900 3495343..3496119 1 NC_022657.1 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains); hypothetical protein 3496119 17443900 AFR_16195 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734574.1 3495343 D 1246995 CDS YP_008734575.1 556566150 17443901 3496145..3496921 1 NC_022657.1 COG0791 Cell wall-associated hydrolases (invasion-associated proteins); NLP/P60 protein 3496921 17443901 AFR_16200 Actinoplanes friuliensis DSM 7358 NLP/P60 protein YP_008734575.1 3496145 D 1246995 CDS YP_008734576.1 556566151 17443902 3497034..3498044 1 NC_022657.1 COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases); oxidoreductase 3498044 17443902 AFR_16205 Actinoplanes friuliensis DSM 7358 oxidoreductase YP_008734576.1 3497034 D 1246995 CDS YP_008734577.1 556566152 17443903 complement(3498052..3499332) 1 NC_022657.1 COG0823 Periplasmic component of the Tol biopolymer transport system; WD40 domain-containing protein 3499332 17443903 AFR_16210 Actinoplanes friuliensis DSM 7358 WD40 domain-containing protein YP_008734577.1 3498052 R 1246995 CDS YP_008734578.1 556566153 17443904 3499566..3500657 1 NC_022657.1 COG4213 ABC-type xylose transport system, periplasmic component; putative ABC transporter substrate-binding protein 3500657 17443904 AFR_16215 Actinoplanes friuliensis DSM 7358 putative ABC transporter substrate-binding protein YP_008734578.1 3499566 D 1246995 CDS YP_008734579.1 556566154 17443905 3500713..3501546 1 NC_022657.1 COG1129 ABC-type sugar transport system, ATPase component; putative ABC transporter ATP-binding protein 3501546 17443905 AFR_16220 Actinoplanes friuliensis DSM 7358 putative ABC transporter ATP-binding protein YP_008734579.1 3500713 D 1246995 CDS YP_008734580.1 556566155 17443906 3501543..3502799 1 NC_022657.1 COG4214 ABC-type xylose transport system, permease component; ABC transporter permease 3502799 17443906 AFR_16225 Actinoplanes friuliensis DSM 7358 ABC transporter permease YP_008734580.1 3501543 D 1246995 CDS YP_008734581.1 556566156 17443907 3502796..3504010 1 NC_022657.1 COG1940 Transcriptional regulator/sugar kinase; putative sugar kinase 3504010 17443907 AFR_16230 Actinoplanes friuliensis DSM 7358 putative sugar kinase YP_008734581.1 3502796 D 1246995 CDS YP_008734582.1 556566157 17443908 3504121..3504372 1 NC_022657.1 hypothetical protein 3504372 17443908 AFR_16235 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734582.1 3504121 D 1246995 CDS YP_008734583.1 556566158 17443909 3504419..3506434 1 NC_022657.1 hypothetical protein 3506434 17443909 AFR_16240 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734583.1 3504419 D 1246995 CDS YP_008734584.1 556566159 17443910 complement(3506396..3506968) 1 NC_022657.1 hypothetical protein 3506968 17443910 AFR_16245 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734584.1 3506396 R 1246995 CDS YP_008734585.1 556566160 17443911 3507113..3509035 1 NC_022657.1 COG4585 Signal transduction histidine kinase; Two component signal transduction histidine kinase 3509035 17443911 AFR_16250 Actinoplanes friuliensis DSM 7358 Two component signal transduction histidine kinase YP_008734585.1 3507113 D 1246995 CDS YP_008734586.1 556566161 17443912 3509026..3509670 1 NC_022657.1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; LuxR family two component transcriptional regulator 3509670 17443912 AFR_16255 Actinoplanes friuliensis DSM 7358 LuxR family two component transcriptional regulator YP_008734586.1 3509026 D 1246995 CDS YP_008734587.1 556566162 17443913 complement(3509678..3509854) 1 NC_022657.1 COG5515 Uncharacterized conserved small protein; hypothetical protein 3509854 17443913 AFR_16260 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734587.1 3509678 R 1246995 CDS YP_008734588.1 556566163 17443914 3509894..3510604 1 NC_022657.1 COG1309 Transcriptional regulator; Tetracycline repressor protein class H 3510604 17443914 AFR_16265 Actinoplanes friuliensis DSM 7358 Tetracycline repressor protein class H YP_008734588.1 3509894 D 1246995 CDS YP_008734589.1 556566164 17443915 3510601..3511740 1 NC_022657.1 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases; kynurenine 3-monooxygenase 3511740 17443915 AFR_16270 Actinoplanes friuliensis DSM 7358 kynurenine 3-monooxygenase YP_008734589.1 3510601 D 1246995 CDS YP_008734590.1 556566165 17443916 3511815..3512552 1 NC_022657.1 hypothetical protein 3512552 17443916 AFR_16275 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734590.1 3511815 D 1246995 CDS YP_008734591.1 556566166 17443917 complement(3512583..3513401) 1 NC_022657.1 COG1262 Uncharacterized conserved protein; hypothetical protein 3513401 17443917 AFR_16280 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734591.1 3512583 R 1246995 CDS YP_008734592.1 556566167 17443918 3513525..3514022 1 NC_022657.1 hypothetical protein 3514022 17443918 AFR_16285 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734592.1 3513525 D 1246995 CDS YP_008734593.1 556566168 17443919 3514022..3515392 1 NC_022657.1 hypothetical protein 3515392 17443919 AFR_16290 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734593.1 3514022 D 1246995 CDS YP_008734594.1 556566169 17443920 3515389..3516687 1 NC_022657.1 hypothetical protein 3516687 17443920 AFR_16295 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734594.1 3515389 D 1246995 CDS YP_008734595.1 556566170 17443921 3516712..3517824 1 NC_022657.1 COG0714 MoxR-like ATPases; putative ATPase 3517824 17443921 AFR_16300 Actinoplanes friuliensis DSM 7358 putative ATPase YP_008734595.1 3516712 D 1246995 CDS YP_008734596.1 556566171 17443922 3517821..3520601 1 NC_022657.1 COG0399 Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; hypothetical protein 3520601 17443922 AFR_16305 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734596.1 3517821 D 1246995 CDS YP_008734597.1 556566172 17443923 3520978..3522375 1 NC_022657.1 hypothetical protein 3522375 17443923 AFR_16310 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734597.1 3520978 D 1246995 CDS YP_008734598.1 556566173 17443924 3522730..3522924 1 NC_022657.1 hypothetical protein 3522924 17443924 AFR_16315 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734598.1 3522730 D 1246995 CDS YP_008734599.1 556566174 17443925 complement(3522975..3525341) 1 NC_022657.1 hypothetical protein 3525341 17443925 AFR_16320 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734599.1 3522975 R 1246995 CDS YP_008734600.1 556566175 17443926 complement(3525338..3527152) 1 NC_022657.1 hypothetical protein 3527152 17443926 AFR_16325 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734600.1 3525338 R 1246995 CDS YP_008734601.1 556566176 17443927 complement(3527152..3527448) 1 NC_022657.1 hypothetical protein 3527448 17443927 AFR_16330 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734601.1 3527152 R 1246995 CDS YP_008734602.1 556566177 17443928 complement(3527449..3528852) 1 NC_022657.1 COG0515 Serine/threonine protein kinase; hypothetical protein 3528852 17443928 AFR_16335 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734602.1 3527449 R 1246995 CDS YP_008734603.1 556566178 17443929 complement(3528856..3529566) 1 NC_022657.1 hypothetical protein 3529566 17443929 AFR_16340 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734603.1 3528856 R 1246995 CDS YP_008734604.1 556566179 17443930 complement(3529563..3532919) 1 NC_022657.1 COG0772 Bacterial cell division membrane protein; peptidoglycan glycosyltransferase 3532919 17443930 AFR_16345 Actinoplanes friuliensis DSM 7358 peptidoglycan glycosyltransferase YP_008734604.1 3529563 R 1246995 CDS YP_008734605.1 556566180 17443931 complement(3533205..3533933) 1 NC_022657.1 COG0491 Zn-dependent hydrolases, including glyoxylases; hypothetical protein 3533933 17443931 AFR_16350 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734605.1 3533205 R 1246995 CDS YP_008734606.1 556566181 17443932 complement(3533930..3534844) 1 NC_022657.1 COG0583 Transcriptional regulator; LysR family transcriptional regulator 3534844 17443932 AFR_16355 Actinoplanes friuliensis DSM 7358 LysR family transcriptional regulator YP_008734606.1 3533930 R 1246995 CDS YP_008734607.1 556566182 17443933 3534932..3535735 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); short chain dehydrogenase 3535735 17443933 AFR_16360 Actinoplanes friuliensis DSM 7358 short chain dehydrogenase YP_008734607.1 3534932 D 1246995 CDS YP_008734608.1 556566183 17443934 complement(3535740..3537353) 1 NC_022657.1 hypothetical protein 3537353 17443934 AFR_16365 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734608.1 3535740 R 1246995 CDS YP_008734609.1 556566184 17443935 complement(3537471..3538352) 1 NC_022657.1 COG0382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases; UbiA prenyltransferase 3538352 17443935 AFR_16370 Actinoplanes friuliensis DSM 7358 UbiA prenyltransferase YP_008734609.1 3537471 R 1246995 CDS YP_008734610.1 556566185 17443936 3538480..3539475 1 NC_022657.1 COG2376 Dihydroxyacetone kinase; dihydroxyacetone kinase subunit DhaK 3539475 17443936 AFR_16375 Actinoplanes friuliensis DSM 7358 dihydroxyacetone kinase subunit DhaK YP_008734610.1 3538480 D 1246995 CDS YP_008734611.1 556566186 17443937 3539436..3540113 1 NC_022657.1 COG2376 Dihydroxyacetone kinase; dihydroxyacetone kinase subunit DhaL 3540113 17443937 AFR_16380 Actinoplanes friuliensis DSM 7358 dihydroxyacetone kinase subunit DhaL YP_008734611.1 3539436 D 1246995 CDS YP_008734612.1 556566187 17443938 3540119..3542488 1 NC_022657.1 COG3412 Uncharacterized protein conserved in bacteria; multiphosphoryl transfer protein (MTP) 3542488 17443938 AFR_16385 Actinoplanes friuliensis DSM 7358 multiphosphoryl transfer protein (MTP) YP_008734612.1 3540119 D 1246995 CDS YP_008734613.1 556566188 17443939 3542525..3543736 1 NC_022657.1 COG0477 Permeases of the major facilitator superfamily; major facilitator superfamily protein 3543736 17443939 AFR_16390 Actinoplanes friuliensis DSM 7358 major facilitator superfamily protein YP_008734613.1 3542525 D 1246995 CDS YP_008734614.1 556566189 17443940 3543845..3544123 1 NC_022657.1 hypothetical protein 3544123 17443940 AFR_16395 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734614.1 3543845 D 1246995 CDS YP_008734615.1 556566190 17443941 complement(3544133..3544867) 1 NC_022657.1 COG0412 Dienelactone hydrolase and related enzymes; putative dienelactone hydrolase family protein 3544867 17443941 AFR_16400 Actinoplanes friuliensis DSM 7358 putative dienelactone hydrolase family protein YP_008734615.1 3544133 R 1246995 CDS YP_008734616.1 556566191 17443942 3544981..3546048 1 NC_022657.1 hypothetical protein 3546048 17443942 AFR_16405 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734616.1 3544981 D 1246995 CDS YP_008734617.1 556566192 17443943 complement(3546020..3546652) 1 NC_022657.1 COG3979 Uncharacterized protein contain chitin-binding domain type 3; PKD domain-containing protein 3546652 17443943 AFR_16410 Actinoplanes friuliensis DSM 7358 PKD domain-containing protein YP_008734617.1 3546020 R 1246995 CDS YP_008734618.1 556566193 17443944 complement(3546696..3547829) 1 NC_022657.1 hypothetical protein 3547829 17443944 AFR_16415 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734618.1 3546696 R 1246995 CDS YP_008734619.1 556566194 17443945 complement(3547844..3548353) 1 NC_022657.1 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; putative RNA polymerase ECF-subfamily sigma factor 3548353 17443945 AFR_16420 Actinoplanes friuliensis DSM 7358 putative RNA polymerase ECF-subfamily sigma factor YP_008734619.1 3547844 R 1246995 CDS YP_008734620.1 556566195 17443946 3548685..3549764 1 NC_022657.1 COG1404 Subtilisin-like serine proteases; peptidase S8 and S53 subtilisin kexin sedolisin 3549764 17443946 AFR_16425 Actinoplanes friuliensis DSM 7358 peptidase S8 and S53 subtilisin kexin sedolisin YP_008734620.1 3548685 D 1246995 CDS YP_008734621.1 556566196 17443947 3549772..3551022 1 NC_022657.1 COG0477 Permeases of the major facilitator superfamily; antibiotic efflux protein 3551022 17443947 AFR_16430 Actinoplanes friuliensis DSM 7358 antibiotic efflux protein YP_008734621.1 3549772 D 1246995 CDS YP_008734622.1 556566197 17443948 complement(3551009..3552445) 1 NC_022657.1 hypothetical protein 3552445 17443948 AFR_16435 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734622.1 3551009 R 1246995 CDS YP_008734623.1 556566198 17443949 complement(3552442..3552858) 1 NC_022657.1 COG1051 ADP-ribose pyrophosphatase; NUDIX hydrolase 3552858 17443949 AFR_16440 Actinoplanes friuliensis DSM 7358 NUDIX hydrolase YP_008734623.1 3552442 R 1246995 CDS YP_008734624.1 556566199 17443950 complement(3552893..3554314) 1 NC_022657.1 COG3940 Predicted beta-xylosidase; putative glycosyl hydrolase 3554314 17443950 AFR_16445 Actinoplanes friuliensis DSM 7358 putative glycosyl hydrolase YP_008734624.1 3552893 R 1246995 CDS YP_008734625.1 556566200 17443951 3554447..3555019 1 NC_022657.1 COG3153 Predicted acetyltransferase; N-acetyltransferase GCN5 3555019 17443951 AFR_16450 Actinoplanes friuliensis DSM 7358 N-acetyltransferase GCN5 YP_008734625.1 3554447 D 1246995 CDS YP_008734626.1 556566201 17443952 complement(3555088..3556251) 1 NC_022657.1 hypothetical protein 3556251 17443952 AFR_16455 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734626.1 3555088 R 1246995 CDS YP_008734627.1 556566202 17443953 3556426..3557826 1 NC_022657.1 COG0531 Amino acid transporters; hypothetical protein 3557826 17443953 AFR_16460 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734627.1 3556426 D 1246995 CDS YP_008734628.1 556566203 17443954 3557900..3558439 1 NC_022657.1 hypothetical protein 3558439 17443954 AFR_16465 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734628.1 3557900 D 1246995 CDS YP_008734629.1 556566204 17443955 complement(3558474..3559289) 1 NC_022657.1 COG1409 Predicted phosphohydrolases; 3',5'-cyclic-nucleotide phosphodiesterase 3559289 17443955 AFR_16470 Actinoplanes friuliensis DSM 7358 3',5'-cyclic-nucleotide phosphodiesterase YP_008734629.1 3558474 R 1246995 CDS YP_008734630.1 556566205 17443956 complement(3559299..3559898) 1 NC_022657.1 COG1309 Transcriptional regulator; HTH-type transcriptional regulator betI 3559898 17443956 AFR_16475 Actinoplanes friuliensis DSM 7358 HTH-type transcriptional regulator betI YP_008734630.1 3559299 R 1246995 CDS YP_008734631.1 556566206 17443957 3560026..3561507 1 NC_022657.1 COG0477 Permeases of the major facilitator superfamily; putative MFS transporter 3561507 17443957 AFR_16480 Actinoplanes friuliensis DSM 7358 putative MFS transporter YP_008734631.1 3560026 D 1246995 CDS YP_008734632.1 556566207 17443958 3561593..3562456 1 NC_022657.1 COG0708 Exonuclease III; hypothetical protein 3562456 17443958 AFR_16485 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734632.1 3561593 D 1246995 CDS YP_008734633.1 556566208 17443959 complement(3562505..3563212) 1 NC_022657.1 hypothetical protein 3563212 17443959 AFR_16490 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734633.1 3562505 R 1246995 CDS YP_008734634.1 556566209 17443960 complement(3563254..3564507) 1 NC_022657.1 COG4102 Uncharacterized protein conserved in bacteria; hypothetical protein 3564507 17443960 AFR_16495 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734634.1 3563254 R 1246995 CDS YP_008734635.1 556566210 17443961 complement(3564513..3566000) 1 NC_022657.1 COG5267 Uncharacterized protein conserved in bacteria; hypothetical protein 3566000 17443961 AFR_16500 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734635.1 3564513 R 1246995 CDS YP_008734636.1 556566211 17443962 complement(3566112..3567554) 1 NC_022657.1 COG1004 Predicted UDP-glucose 6-dehydrogenase; nucleotide sugar dehydrogenase 3567554 17443962 AFR_16505 Actinoplanes friuliensis DSM 7358 nucleotide sugar dehydrogenase YP_008734636.1 3566112 R 1246995 CDS YP_008734637.1 556566212 17443963 complement(3567551..3569074) 1 NC_022657.1 COG5305 Predicted membrane protein; hypothetical protein 3569074 17443963 AFR_16510 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734637.1 3567551 R 1246995 CDS YP_008734638.1 556566213 17443964 complement(3569082..3571217) 1 NC_022657.1 COG1835 Predicted acyltransferases; putative acyltransferase 3571217 17443964 AFR_16515 Actinoplanes friuliensis DSM 7358 putative acyltransferase YP_008734638.1 3569082 R 1246995 CDS YP_008734639.1 556566214 17443965 complement(3571214..3572770) 1 NC_022657.1 COG1215 Glycosyltransferases, probably involved in cell wall biogenesis; cellulose synthase 3572770 17443965 AFR_16520 Actinoplanes friuliensis DSM 7358 cellulose synthase YP_008734639.1 3571214 R 1246995 CDS YP_008734640.1 556566215 17443966 3574211..3575191 1 NC_022657.1 hypothetical protein 3575191 17443966 AFR_16535 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734640.1 3574211 D 1246995 CDS YP_008734641.1 556566216 17443967 3575322..3576506 1 NC_022657.1 COG0477 Permeases of the major facilitator superfamily; major facilitator transporter 3576506 17443967 AFR_16540 Actinoplanes friuliensis DSM 7358 major facilitator transporter YP_008734641.1 3575322 D 1246995 CDS YP_008734642.1 556566217 17443968 3576544..3577992 1 NC_022657.1 COG2986 Histidine ammonia-lyase; putative phenylalanine/histidine ammonia-lyase 3577992 17443968 AFR_16545 Actinoplanes friuliensis DSM 7358 putative phenylalanine/histidine ammonia-lyase YP_008734642.1 3576544 D 1246995 CDS YP_008734643.1 556566218 17443969 complement(3577960..3578481) 1 NC_022657.1 putative cysteine dioxygenase type I 3578481 17443969 AFR_16550 Actinoplanes friuliensis DSM 7358 putative cysteine dioxygenase type I YP_008734643.1 3577960 R 1246995 CDS YP_008734644.1 556566219 17443970 complement(3578478..3579374) 1 NC_022657.1 putative amidohydrolase 3579374 17443970 AFR_16555 Actinoplanes friuliensis DSM 7358 putative amidohydrolase YP_008734644.1 3578478 R 1246995 CDS YP_008734645.1 556566220 17443971 3580602..3581282 1 NC_022657.1 COG2203 FOG: GAF domain; hypothetical protein 3581282 17443971 AFR_16570 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734645.1 3580602 D 1246995 CDS YP_008734646.1 556566221 17443972 complement(3581263..3582195) 1 NC_022657.1 COG0859 ADP-heptose:LPS heptosyltransferase; putative glycosyltransferase 3582195 17443972 AFR_16575 Actinoplanes friuliensis DSM 7358 putative glycosyltransferase YP_008734646.1 3581263 R 1246995 CDS YP_008734647.1 556566222 17443973 complement(3582192..3582866) 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); putative short-chain dehydrogenase 3582866 17443973 AFR_16580 Actinoplanes friuliensis DSM 7358 putative short-chain dehydrogenase YP_008734647.1 3582192 R 1246995 CDS YP_008734648.1 556566223 17443974 complement(3582863..3584263) 1 NC_022657.1 COG2870 ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase; putative bifunctional cytidylyltransferase/PfkB-family carbohydrate kinase 3584263 17443974 AFR_16585 Actinoplanes friuliensis DSM 7358 putative bifunctional cytidylyltransferase/PfkB-family carbohydrate kinase YP_008734648.1 3582863 R 1246995 CDS YP_008734649.1 556566224 17443975 complement(3584260..3584874) 1 NC_022657.1 COG0279 Phosphoheptose isomerase; putative sugar isomerase 3584874 17443975 AFR_16590 Actinoplanes friuliensis DSM 7358 putative sugar isomerase YP_008734649.1 3584260 R 1246995 CDS YP_008734650.1 556566225 17443976 complement(3584871..3586064) 1 NC_022657.1 COG0438 Glycosyltransferase; group 1 glycosyl transferase 3586064 17443976 AFR_16595 Actinoplanes friuliensis DSM 7358 group 1 glycosyl transferase YP_008734650.1 3584871 R 1246995 CDS YP_008734651.1 556566226 17443977 complement(3586067..3586990) 1 NC_022657.1 COG0438 Glycosyltransferase; putative glycosyltransferase 3586990 17443977 AFR_16600 Actinoplanes friuliensis DSM 7358 putative glycosyltransferase YP_008734651.1 3586067 R 1246995 CDS YP_008734652.1 556566227 17443978 complement(3586987..3588546) 1 NC_022657.1 COG0241 Histidinol phosphatase and related phosphatases; putative glycosyltransferase 3588546 17443978 AFR_16605 Actinoplanes friuliensis DSM 7358 putative glycosyltransferase YP_008734652.1 3586987 R 1246995 CDS YP_008734653.1 556566228 17443979 complement(3588543..3589568) 1 NC_022657.1 COG0463 Glycosyltransferases involved in cell wall biogenesis; putative 55.3 kDa protein in thcA 5'region 3589568 17443979 AFR_16610 Actinoplanes friuliensis DSM 7358 putative 55.3 kDa protein in thcA 5'region YP_008734653.1 3588543 R 1246995 CDS YP_008734654.1 556566229 17443980 complement(3589565..3591208) 1 NC_022657.1 COG2192 Predicted carbamoyl transferase, NodU family; carbamoyltransferase 3591208 17443980 AFR_16615 Actinoplanes friuliensis DSM 7358 carbamoyltransferase YP_008734654.1 3589565 R 1246995 CDS YP_008734655.1 556566230 17443981 3591348..3592754 1 NC_022657.1 COG1012 NAD-dependent aldehyde dehydrogenases; putative aldehyde dehydrogenase 3592754 17443981 AFR_16620 Actinoplanes friuliensis DSM 7358 putative aldehyde dehydrogenase YP_008734655.1 3591348 D 1246995 CDS YP_008734656.1 556566231 17443982 complement(3592724..3593458) 1 NC_022657.1 COG3707 Response regulator with putative antiterminator output domain; ANTAR domain-containing protein 3593458 17443982 AFR_16625 Actinoplanes friuliensis DSM 7358 ANTAR domain-containing protein YP_008734656.1 3592724 R 1246995 CDS YP_008734657.1 556566232 17443983 complement(3593657..3594370) 1 NC_022657.1 COG2203 FOG: GAF domain; ANTAR domain-containing protein 3594370 17443983 AFR_16630 Actinoplanes friuliensis DSM 7358 ANTAR domain-containing protein YP_008734657.1 3593657 R 1246995 CDS YP_008734658.1 556566233 17443984 3594811..3595629 1 NC_022657.1 COG1191 DNA-directed RNA polymerase specialized sigma subunit; RNA polymerase sigma factor rpoD 3595629 17443984 AFR_16635 Actinoplanes friuliensis DSM 7358 RNA polymerase sigma factor rpoD YP_008734658.1 3594811 D 1246995 CDS YP_008734659.1 556566234 17443985 3595746..3596399 1 NC_022657.1 COG0563 Adenylate kinase and related kinases; adenylate kinase 3596399 17443985 AFR_16640 Actinoplanes friuliensis DSM 7358 adenylate kinase YP_008734659.1 3595746 D 1246995 CDS YP_008734660.1 556566235 17443986 3596445..3597254 1 NC_022657.1 COG1120 ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components; cobalamin/Fe3+-siderophore ABC transporter ATPase 3597254 17443986 AFR_16645 Actinoplanes friuliensis DSM 7358 cobalamin/Fe3+-siderophore ABC transporter ATPase YP_008734660.1 3596445 D 1246995 CDS YP_008734661.1 556566236 17443987 3597295..3598293 1 NC_022657.1 COG0614 ABC-type Fe3+-hydroxamate transport system, periplasmic component; periplasmic binding protein 3598293 17443987 AFR_16650 Actinoplanes friuliensis DSM 7358 periplasmic binding protein YP_008734661.1 3597295 D 1246995 CDS YP_008734662.1 556566237 17443988 3598296..3600410 1 NC_022657.1 COG0609 ABC-type Fe3+-siderophore transport system, permease component; iron-hydroxamate transporter permease subunit 3600410 17443988 AFR_16655 Actinoplanes friuliensis DSM 7358 iron-hydroxamate transporter permease subunit YP_008734662.1 3598296 D 1246995 CDS YP_008734663.1 556566238 17444003 complement(3601988..3602833) 1 NC_022657.1 hypothetical protein 3602833 17444003 AFR_16660 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734663.1 3601988 R 1246995 CDS YP_008734664.1 556566239 17444004 complement(3602830..3603942) 1 NC_022657.1 COG0372 Citrate synthase; citrate synthase 2 3603942 17444004 AFR_16665 Actinoplanes friuliensis DSM 7358 citrate synthase 2 YP_008734664.1 3602830 R 1246995 CDS YP_008734665.1 556566240 17444005 3604010..3605191 1 NC_022657.1 COG0789 Predicted transcriptional regulators; citrate synthase 3605191 17444005 AFR_16670 Actinoplanes friuliensis DSM 7358 citrate synthase YP_008734665.1 3604010 D 1246995 CDS YP_008734666.1 556566241 17444006 complement(3605192..3605842) 1 NC_022657.1 hypothetical protein 3605842 17444006 AFR_16675 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734666.1 3605192 R 1246995 CDS YP_008734667.1 556566242 17444007 3605983..3607155 1 NC_022657.1 COG2124 Cytochrome P450; cytochrome P450 3607155 17444007 AFR_16680 Actinoplanes friuliensis DSM 7358 cytochrome P450 YP_008734667.1 3605983 D 1246995 CDS YP_008734668.1 556566243 17444008 3607255..3608040 1 NC_022657.1 COG5640 Secreted trypsin-like serine protease; Thrombin-like enzyme gussurobin 3608040 17444008 AFR_16685 Actinoplanes friuliensis DSM 7358 Thrombin-like enzyme gussurobin YP_008734668.1 3607255 D 1246995 CDS YP_008734669.1 556566244 17444009 3608116..3609249 1 NC_022657.1 COG0628 Predicted permease; hypothetical protein 3609249 17444009 AFR_16690 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734669.1 3608116 D 1246995 CDS YP_008734670.1 556566245 17444010 complement(3609232..3609897) 1 NC_022657.1 COG0500 SAM-dependent methyltransferases; methyltransferase 3609897 17444010 AFR_16695 Actinoplanes friuliensis DSM 7358 methyltransferase YP_008734670.1 3609232 R 1246995 CDS YP_008734671.1 556566246 17444011 3610185..3610760 1 NC_022657.1 COG3911 Predicted ATPase; ATP-binding protein 3610760 17444011 AFR_16700 Actinoplanes friuliensis DSM 7358 ATP-binding protein YP_008734671.1 3610185 D 1246995 CDS YP_008734672.1 556566247 17444012 complement(3610720..3611604) 1 NC_022657.1 hypothetical protein 3611604 17444012 AFR_16705 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734672.1 3610720 R 1246995 CDS YP_008734673.1 556566248 17444013 complement(3611647..3614415) 1 NC_022657.1 COG2133 Glucose/sorbosone dehydrogenases; hypothetical protein 3614415 17444013 AFR_16710 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734673.1 3611647 R 1246995 CDS YP_008734674.1 556566249 17444014 3614954..3617614 1 NC_022657.1 COG0574 Phosphoenolpyruvate synthase/pyruvate phosphate dikinase; putative phosphoenolpyruvate synthase 3617614 17444014 AFR_16715 Actinoplanes friuliensis DSM 7358 putative phosphoenolpyruvate synthase YP_008734674.1 3614954 D 1246995 CDS YP_008734675.1 556566250 17444015 complement(3617581..3618477) 1 NC_022657.1 COG0823 Periplasmic component of the Tol biopolymer transport system; protein tolB 3618477 17444015 AFR_16720 Actinoplanes friuliensis DSM 7358 protein tolB YP_008734675.1 3617581 R 1246995 CDS YP_008734676.1 556566251 17444016 complement(3619056..3620261) 1 NC_022657.1 COG0577 ABC-type antimicrobial peptide transport system, permease component; hypothetical protein 3620261 17444016 AFR_16725 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734676.1 3619056 R 1246995 CDS YP_008734677.1 556566252 17444017 complement(3620254..3620925) 1 NC_022657.1 COG1136 ABC-type antimicrobial peptide transport system, ATPase component; putative ABC transporter ATP-binding protein 3620925 17444017 AFR_16730 Actinoplanes friuliensis DSM 7358 putative ABC transporter ATP-binding protein YP_008734677.1 3620254 R 1246995 CDS YP_008734678.1 556566253 17444018 complement(3620922..3622367) 1 NC_022657.1 COG3409 Putative peptidoglycan-binding domain-containing protein; peptidoglycan-binding domain 1 protein 3622367 17444018 AFR_16735 Actinoplanes friuliensis DSM 7358 peptidoglycan-binding domain 1 protein YP_008734678.1 3620922 R 1246995 CDS YP_008734679.1 556566254 17444019 complement(3622399..3623352) 1 NC_022657.1 hypothetical protein 3623352 17444019 AFR_16740 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734679.1 3622399 R 1246995 CDS YP_008734680.1 556566255 17444020 complement(3623526..3623900) 1 NC_022657.1 hypothetical protein 3623900 17444020 AFR_16745 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734680.1 3623526 R 1246995 CDS YP_008734681.1 556566256 17444021 complement(3624441..3625226) 1 NC_022657.1 hypothetical protein 3625226 17444021 AFR_16750 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734681.1 3624441 R 1246995 CDS YP_008734682.1 556566257 17444022 complement(3625223..3625741) 1 NC_022657.1 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; RNA polymerase ECF sigma factor 3625741 17444022 AFR_16755 Actinoplanes friuliensis DSM 7358 RNA polymerase ECF sigma factor YP_008734682.1 3625223 R 1246995 CDS YP_008734683.1 556566258 17444023 complement(3625833..3626810) 1 NC_022657.1 COG0584 Glycerophosphoryl diester phosphodiesterase; glycerophosphoryl diester phosphodiesterase 3626810 17444023 AFR_16760 Actinoplanes friuliensis DSM 7358 glycerophosphoryl diester phosphodiesterase YP_008734683.1 3625833 R 1246995 CDS YP_008734684.1 556566259 17444024 complement(3627023..3627733) 1 NC_022657.1 hypothetical protein 3627733 17444024 AFR_16765 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734684.1 3627023 R 1246995 CDS YP_008734685.1 556566260 17444025 complement(3627730..3628173) 1 NC_022657.1 COG1846 Transcriptional regulators; putative MarR-family transcriptional regulator 3628173 17444025 AFR_16770 Actinoplanes friuliensis DSM 7358 putative MarR-family transcriptional regulator YP_008734685.1 3627730 R 1246995 CDS YP_008734686.1 556566261 17444026 complement(3628461..3629456) 1 NC_022657.1 COG0809 S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase); tRNA ribosyltransferase-isomerase 3629456 17444026 AFR_16775 Actinoplanes friuliensis DSM 7358 tRNA ribosyltransferase-isomerase YP_008734686.1 3628461 R 1246995 CDS YP_008734687.1 556566262 17444027 complement(3629456..3630166) 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); short-chain dehydrogenase/reductase SDR 3630166 17444027 AFR_16780 Actinoplanes friuliensis DSM 7358 short-chain dehydrogenase/reductase SDR YP_008734687.1 3629456 R 1246995 CDS YP_008734688.1 556566263 17444028 3630290..3631411 1 NC_022657.1 COG2203 FOG: GAF domain; two-component system sensor kinase 3631411 17444028 AFR_16785 Actinoplanes friuliensis DSM 7358 two-component system sensor kinase YP_008734688.1 3630290 D 1246995 CDS YP_008734689.1 556566264 17444029 3631404..3632036 1 NC_022657.1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; two-component system response regulator 3632036 17444029 AFR_16790 Actinoplanes friuliensis DSM 7358 two-component system response regulator YP_008734689.1 3631404 D 1246995 CDS YP_008734690.1 556566265 17444030 3632099..3632521 1 NC_022657.1 COG1846 Transcriptional regulators; transcriptional regulator 3632521 17444030 AFR_16795 Actinoplanes friuliensis DSM 7358 transcriptional regulator YP_008734690.1 3632099 D 1246995 CDS YP_008734691.1 556566266 17444031 3632874..3634313 1 NC_022657.1 COG0534 Na+-driven multidrug efflux pump; MATE family efflux protein 3634313 17444031 AFR_16800 Actinoplanes friuliensis DSM 7358 MATE family efflux protein YP_008734691.1 3632874 D 1246995 CDS YP_008734692.1 556566267 17444032 complement(3634338..3635144) 1 NC_022657.1 hypothetical protein 3635144 17444032 AFR_16805 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734692.1 3634338 R 1246995 CDS YP_008734693.1 556566268 17444033 complement(3635156..3635845) 1 NC_022657.1 COG3599 Cell division initiation protein; Laminin subunit beta-2 3635845 17444033 AFR_16810 Actinoplanes friuliensis DSM 7358 Laminin subunit beta-2 YP_008734693.1 3635156 R 1246995 CDS YP_008734694.1 556566269 17444034 3636051..3637130 1 NC_022657.1 COG1609 Transcriptional regulators; LacI family transcriptional regulator 3637130 17444034 AFR_16815 Actinoplanes friuliensis DSM 7358 LacI family transcriptional regulator YP_008734694.1 3636051 D 1246995 CDS YP_008734695.1 556566270 17444035 complement(3637031..3638281) 1 NC_022657.1 COG3875 Uncharacterized conserved protein; hypothetical protein 3638281 17444035 AFR_16820 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734695.1 3637031 R 1246995 CDS YP_008734696.1 556566271 17444036 complement(3638278..3639135) 1 NC_022657.1 COG1082 Sugar phosphate isomerases/epimerases; hypothetical protein 3639135 17444036 AFR_16825 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734696.1 3638278 R 1246995 CDS YP_008734697.1 556566272 17444037 complement(3639132..3640178) 1 NC_022657.1 COG0673 Predicted dehydrogenases and related proteins; oxidoreductase 3640178 17444037 AFR_16830 Actinoplanes friuliensis DSM 7358 oxidoreductase YP_008734697.1 3639132 R 1246995 CDS YP_008734698.1 556566273 17444038 complement(3640175..3641002) 1 NC_022657.1 COG1082 Sugar phosphate isomerases/epimerases; xylose isomerase domain-containing protein TIM barrel 3641002 17444038 AFR_16835 Actinoplanes friuliensis DSM 7358 xylose isomerase domain-containing protein TIM barrel YP_008734698.1 3640175 R 1246995 CDS YP_008734699.1 556566274 17444039 complement(3641023..3642006) 1 NC_022657.1 COG0673 Predicted dehydrogenases and related proteins; dehydrogenase 3642006 17444039 AFR_16840 Actinoplanes friuliensis DSM 7358 dehydrogenase YP_008734699.1 3641023 R 1246995 CDS YP_008734700.1 556566275 17444040 complement(3642003..3642866) 1 NC_022657.1 COG0395 ABC-type sugar transport system, permease component; binding-protein-dependent transport system inner membrane protein 3642866 17444040 AFR_16845 Actinoplanes friuliensis DSM 7358 binding-protein-dependent transport system inner membrane protein YP_008734700.1 3642003 R 1246995 CDS YP_008734701.1 556566276 17444041 complement(3642863..3643849) 1 NC_022657.1 COG1175 ABC-type sugar transport systems, permease components; ABC transporter permease protein y4oQ 3643849 17444041 AFR_16850 Actinoplanes friuliensis DSM 7358 ABC transporter permease protein y4oQ YP_008734701.1 3642863 R 1246995 CDS YP_008734702.1 556566277 17444042 complement(3643856..3645163) 1 NC_022657.1 COG1653 ABC-type sugar transport system, periplasmic component; disaccharide-binding protein 3645163 17444042 AFR_16855 Actinoplanes friuliensis DSM 7358 disaccharide-binding protein YP_008734702.1 3643856 R 1246995 CDS YP_008734703.1 556566278 17444043 3645334..3646743 1 NC_022657.1 COG1904 Glucuronate isomerase; glucuronate isomerase 3646743 17444043 AFR_16860 Actinoplanes friuliensis DSM 7358 glucuronate isomerase YP_008734703.1 3645334 D 1246995 CDS YP_008734704.1 556566279 17444044 3646740..3647957 1 NC_022657.1 COG0246 Mannitol-1-phosphate/altronate dehydrogenases; mannitol dehydrogenase 3647957 17444044 AFR_16865 Actinoplanes friuliensis DSM 7358 mannitol dehydrogenase YP_008734704.1 3646740 D 1246995 CDS YP_008734705.1 556566280 17444045 3647959..3648813 1 NC_022657.1 COG0500 SAM-dependent methyltransferases; type 11 methyltransferase 3648813 17444045 AFR_16870 Actinoplanes friuliensis DSM 7358 type 11 methyltransferase YP_008734705.1 3647959 D 1246995 CDS YP_008734706.1 556566281 17444046 complement(3648785..3649324) 1 NC_022657.1 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins; acetyltransferase 3649324 17444046 AFR_16875 Actinoplanes friuliensis DSM 7358 acetyltransferase YP_008734706.1 3648785 R 1246995 CDS YP_008734707.1 556566282 17444047 complement(3649369..3650154) 1 NC_022657.1 COG0666 FOG: Ankyrin repeat; Ankyrin 3650154 17444047 AFR_16880 Actinoplanes friuliensis DSM 7358 Ankyrin YP_008734707.1 3649369 R 1246995 CDS YP_008734708.1 556566283 17444048 complement(3650168..3650920) 1 NC_022657.1 COG2755 Lysophospholipase L1 and related esterases; GDSL family lipase 3650920 17444048 AFR_16885 Actinoplanes friuliensis DSM 7358 GDSL family lipase YP_008734708.1 3650168 R 1246995 CDS YP_008734709.1 556566284 17444049 3651039..3651401 1 NC_022657.1 COG4911 Uncharacterized conserved protein; hypothetical protein 3651401 17444049 AFR_16890 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734709.1 3651039 D 1246995 CDS YP_008734710.1 556566285 17444050 complement(3651675..3652184) 1 NC_022657.1 hypothetical protein 3652184 17444050 AFR_16895 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734710.1 3651675 R 1246995 CDS YP_008734711.1 556566286 17444051 3652272..3652643 1 NC_022657.1 hypothetical protein 3652643 17444051 AFR_16900 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734711.1 3652272 D 1246995 CDS YP_008734712.1 556566287 17444052 complement(3652648..3653634) 1 NC_022657.1 COG0451 Nucleoside-diphosphate-sugar epimerases; oxidoreductase 3653634 17444052 AFR_16905 Actinoplanes friuliensis DSM 7358 oxidoreductase YP_008734712.1 3652648 R 1246995 CDS YP_008734713.1 556566288 17444053 3653711..3655144 1 NC_022657.1 COG1012 NAD-dependent aldehyde dehydrogenases; nonphosphorylating glyceraldehyde-3-phosphate dehydrogenase 3655144 17444053 AFR_16910 Actinoplanes friuliensis DSM 7358 nonphosphorylating glyceraldehyde-3-phosphate dehydrogenase YP_008734713.1 3653711 D 1246995 CDS YP_008734714.1 556566289 17444054 complement(3655134..3655601) 1 NC_022657.1 COG1522 Transcriptional regulators; putative HTH-type transcriptional regulator 3655601 17444054 AFR_16915 Actinoplanes friuliensis DSM 7358 putative HTH-type transcriptional regulator YP_008734714.1 3655134 R 1246995 CDS YP_008734715.1 556566290 17444055 3655757..3656827 1 NC_022657.1 COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit; pyruvate dehydrogenase E1 component subunit alpha 3656827 17444055 AFR_16920 Actinoplanes friuliensis DSM 7358 pyruvate dehydrogenase E1 component subunit alpha YP_008734715.1 3655757 D 1246995 CDS YP_008734716.1 556566291 17444056 3656824..3657825 1 NC_022657.1 COG0022 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit; transketolase 3657825 17444056 AFR_16925 Actinoplanes friuliensis DSM 7358 transketolase YP_008734716.1 3656824 D 1246995 CDS YP_008734717.1 556566292 17444057 3657822..3659237 1 NC_022657.1 COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes; branched-chain alpha-keto acid dehydrogenase subunit E2 3659237 17444057 AFR_16930 Actinoplanes friuliensis DSM 7358 branched-chain alpha-keto acid dehydrogenase subunit E2 YP_008734717.1 3657822 D 1246995 CDS YP_008734718.1 556566293 17444058 complement(3659695..3661179) 1 NC_022657.1 COG0477 Permeases of the major facilitator superfamily; putative MFS transporter 3661179 17444058 AFR_16935 Actinoplanes friuliensis DSM 7358 putative MFS transporter YP_008734718.1 3659695 R 1246995 CDS YP_008734719.1 556566294 17444059 complement(3661229..3661855) 1 NC_022657.1 hypothetical protein 3661855 17444059 AFR_16940 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734719.1 3661229 R 1246995 CDS YP_008734720.1 556566295 17444060 complement(3661915..3662808) 1 NC_022657.1 COG1609 Transcriptional regulators; LacI family transcriptional regulator 3662808 17444060 AFR_16945 Actinoplanes friuliensis DSM 7358 LacI family transcriptional regulator YP_008734720.1 3661915 R 1246995 CDS YP_008734721.1 556566296 17444061 complement(3662977..3663489) 1 NC_022657.1 hypothetical protein 3663489 17444061 AFR_16950 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734721.1 3662977 R 1246995 CDS YP_008734722.1 556566297 17444062 complement(3663563..3664843) 1 NC_022657.1 COG0405 Gamma-glutamyltransferase; tyramine oxidase 3664843 17444062 AFR_16955 Actinoplanes friuliensis DSM 7358 tyramine oxidase YP_008734722.1 3663563 R 1246995 CDS YP_008734723.1 556566298 17444063 complement(3665089..3665646) 1 NC_022657.1 transcriptional regulator domain-containing protein 3665646 17444063 AFR_16960 Actinoplanes friuliensis DSM 7358 transcriptional regulator domain-containing protein YP_008734723.1 3665089 R 1246995 CDS YP_008734724.1 556566299 17444064 3665945..3670291 1 NC_022657.1 COG1404 Subtilisin-like serine proteases; peptidase S8 and S53 subtilisin kexin sedolisin 3670291 17444064 AFR_16965 Actinoplanes friuliensis DSM 7358 peptidase S8 and S53 subtilisin kexin sedolisin YP_008734724.1 3665945 D 1246995 CDS YP_008734725.1 556566300 17444065 complement(3670429..3670953) 1 NC_022657.1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; transcriptional regulator domain-containing protein 3670953 17444065 AFR_16970 Actinoplanes friuliensis DSM 7358 transcriptional regulator domain-containing protein YP_008734725.1 3670429 R 1246995 CDS YP_008734726.1 556566301 17444066 3671275..3671976 1 NC_022657.1 COG3828 Uncharacterized protein conserved in bacteria; hypothetical protein 3671976 17444066 AFR_16975 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734726.1 3671275 D 1246995 CDS YP_008734727.1 556566302 17444067 3671961..3673058 1 NC_022657.1 COG0673 Predicted dehydrogenases and related proteins; oxidoreductase domain-containing protein 3673058 17444067 AFR_16980 Actinoplanes friuliensis DSM 7358 oxidoreductase domain-containing protein YP_008734727.1 3671961 D 1246995 CDS YP_008734728.1 556566303 17444068 complement(3673042..3674532) 1 NC_022657.1 COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); glycosidase 3674532 17444068 AFR_16985 Actinoplanes friuliensis DSM 7358 glycosidase YP_008734728.1 3673042 R 1246995 CDS YP_008734729.1 556566304 17444069 complement(3674600..3675355) 1 NC_022657.1 hypothetical protein 3675355 17444069 AFR_16990 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734729.1 3674600 R 1246995 CDS YP_008734730.1 556566305 17444070 3675494..3678496 1 NC_022657.1 COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain; putative diguanylate cyclase/phosphodiesterase with PAS sensor 3678496 17444070 AFR_16995 Actinoplanes friuliensis DSM 7358 putative diguanylate cyclase/phosphodiesterase with PAS sensor YP_008734730.1 3675494 D 1246995 CDS YP_008734731.1 556566306 17444071 3678559..3679818 1 NC_022657.1 COG0156 7-keto-8-aminopelargonate synthetase and related enzymes; 8-amino-7-oxononanoate synthase 3679818 17444071 AFR_17000 Actinoplanes friuliensis DSM 7358 8-amino-7-oxononanoate synthase YP_008734731.1 3678559 D 1246995 CDS YP_008734732.1 556566307 17444072 complement(3679798..3680298) 1 NC_022657.1 acetyltransferase 3680298 17444072 AFR_17005 Actinoplanes friuliensis DSM 7358 acetyltransferase YP_008734732.1 3679798 R 1246995 CDS YP_008734733.1 556566308 17444073 complement(3680811..3681602) 1 NC_022657.1 hypothetical protein 3681602 17444073 AFR_17010 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734733.1 3680811 R 1246995 CDS YP_008734734.1 556566309 17444074 3681709..3682980 1 NC_022657.1 COG0515 Serine/threonine protein kinase; serine/threonine protein kinase 3682980 17444074 AFR_17015 Actinoplanes friuliensis DSM 7358 serine/threonine protein kinase YP_008734734.1 3681709 D 1246995 CDS YP_008734735.1 556566310 17444075 3682984..3683964 1 NC_022657.1 COG4427 Uncharacterized protein conserved in bacteria; hypothetical protein 3683964 17444075 AFR_17020 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734735.1 3682984 D 1246995 CDS YP_008734736.1 556566311 17444076 complement(3683957..3684163) 1 NC_022657.1 hypothetical protein 3684163 17444076 AFR_17025 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734736.1 3683957 R 1246995 CDS YP_008734737.1 556566312 17444077 complement(3684160..3684375) 1 NC_022657.1 hypothetical protein 3684375 17444077 AFR_17030 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734737.1 3684160 R 1246995 CDS YP_008734738.1 556566313 17444078 complement(3685097..3685609) 1 NC_022657.1 hypothetical protein 3685609 17444078 AFR_17035 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734738.1 3685097 R 1246995 CDS YP_008734739.1 556566314 17444079 complement(3685623..3686153) 1 NC_022657.1 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; ECF subfamily RNA polymerase sigma-24 subunit 3686153 17444079 AFR_17040 Actinoplanes friuliensis DSM 7358 ECF subfamily RNA polymerase sigma-24 subunit YP_008734739.1 3685623 R 1246995 CDS YP_008734740.1 556566315 17444080 3686201..3687130 1 NC_022657.1 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase; putative diacylglycerol kinase 3687130 17444080 AFR_17045 Actinoplanes friuliensis DSM 7358 putative diacylglycerol kinase YP_008734740.1 3686201 D 1246995 CDS YP_008734741.1 556566316 17444081 complement(3687183..3687785) 1 NC_022657.1 COG1309 Transcriptional regulator; TetR family transcriptional regulator 3687785 17444081 AFR_17050 Actinoplanes friuliensis DSM 7358 TetR family transcriptional regulator YP_008734741.1 3687183 R 1246995 CDS YP_008734742.1 556566317 17444082 3687873..3689006 1 NC_022657.1 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases; FAD dependent oxidoreductase 3689006 17444082 AFR_17055 Actinoplanes friuliensis DSM 7358 FAD dependent oxidoreductase YP_008734742.1 3687873 D 1246995 CDS YP_008734743.1 556566318 17444083 3689232..3690902 1 NC_022657.1 hypothetical protein 3690902 17444083 AFR_17060 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734743.1 3689232 D 1246995 CDS YP_008734744.1 556566319 17444084 complement(3690907..3691374) 1 NC_022657.1 COG3832 Uncharacterized conserved protein; Activator of Hsp90 ATPase 1 family protein 3691374 17444084 AFR_17065 Actinoplanes friuliensis DSM 7358 Activator of Hsp90 ATPase 1 family protein YP_008734744.1 3690907 R 1246995 CDS YP_008734745.1 556566320 17444085 complement(3691371..3691733) 1 NC_022657.1 COG0640 Predicted transcriptional regulators; regulatory protein ArsR 3691733 17444085 AFR_17070 Actinoplanes friuliensis DSM 7358 regulatory protein ArsR YP_008734745.1 3691371 R 1246995 CDS YP_008734746.1 556566321 17444086 3691732..3692343 1 NC_022657.1 COG0262 Dihydrofolate reductase; bifunctional deaminase-reductase domain-containing protein 3692343 17444086 AFR_17075 Actinoplanes friuliensis DSM 7358 bifunctional deaminase-reductase domain-containing protein YP_008734746.1 3691732 D 1246995 CDS YP_008734747.1 556566322 17444087 complement(3692331..3693803) 1 NC_022657.1 COG0076 Glutamate decarboxylase and related PLP-dependent proteins; pyridoxal-dependent decarboxylase 3693803 17444087 AFR_17080 Actinoplanes friuliensis DSM 7358 pyridoxal-dependent decarboxylase YP_008734747.1 3692331 R 1246995 CDS YP_008734748.1 556566323 17444088 3693882..3696938 1 NC_022657.1 COG2199 FOG: GGDEF domain; Signaling protein ykoW 3696938 17444088 AFR_17085 Actinoplanes friuliensis DSM 7358 Signaling protein ykoW YP_008734748.1 3693882 D 1246995 CDS YP_008734749.1 556566324 17444089 3696974..3698203 1 NC_022657.1 COG0156 7-keto-8-aminopelargonate synthetase and related enzymes; 8-amino-7-oxononanoate synthase 3698203 17444089 AFR_17090 Actinoplanes friuliensis DSM 7358 8-amino-7-oxononanoate synthase YP_008734749.1 3696974 D 1246995 CDS YP_008734750.1 556566325 17444090 3698205..3699473 1 NC_022657.1 COG0477 Permeases of the major facilitator superfamily; major facilitator superfamily protein 3699473 17444090 AFR_17095 Actinoplanes friuliensis DSM 7358 major facilitator superfamily protein YP_008734750.1 3698205 D 1246995 CDS YP_008734751.1 556566326 17444091 3699470..3699871 1 NC_022657.1 hypothetical protein 3699871 17444091 AFR_17100 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734751.1 3699470 D 1246995 CDS YP_008734752.1 556566327 17444092 3699918..3701489 1 NC_022657.1 COG3345 Alpha-galactosidase; alpha-galactosidase 3701489 17444092 AFR_17105 Actinoplanes friuliensis DSM 7358 alpha-galactosidase YP_008734752.1 3699918 D 1246995 CDS YP_008734753.1 556566328 17444093 3701509..3702294 1 NC_022657.1 hypothetical protein 3702294 17444093 AFR_17110 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734753.1 3701509 D 1246995 CDS YP_008734754.1 556566329 17444094 3702373..3702999 1 NC_022657.1 hypothetical protein 3702999 17444094 AFR_17115 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734754.1 3702373 D 1246995 CDS YP_008734755.1 556566330 17444095 3703052..3703945 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); short chain dehydrogenase 3703945 17444095 AFR_17120 Actinoplanes friuliensis DSM 7358 short chain dehydrogenase YP_008734755.1 3703052 D 1246995 CDS YP_008734756.1 556566331 17444096 3703945..3704778 1 NC_022657.1 COG1396 Predicted transcriptional regulators; helix-turn-helix domain-containing protein 3704778 17444096 AFR_17125 Actinoplanes friuliensis DSM 7358 helix-turn-helix domain-containing protein YP_008734756.1 3703945 D 1246995 CDS YP_008734757.1 556566332 17444097 3704855..3706192 1 NC_022657.1 COG1252 NADH dehydrogenase, FAD-containing subunit; NADH dehydrogenase 3706192 17444097 AFR_17130 Actinoplanes friuliensis DSM 7358 NADH dehydrogenase YP_008734757.1 3704855 D 1246995 CDS YP_008734758.1 556566333 17444098 3706257..3706808 1 NC_022657.1 COG0262 Dihydrofolate reductase; hypothetical protein 3706808 17444098 AFR_17135 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734758.1 3706257 D 1246995 CDS YP_008734759.1 556566334 17444099 3706892..3707395 1 NC_022657.1 hypothetical protein 3707395 17444099 AFR_17140 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734759.1 3706892 D 1246995 CDS YP_008734760.1 556566335 17444100 complement(3707500..3708714) 1 NC_022657.1 COG1940 Transcriptional regulator/sugar kinase; ROK family protein 3708714 17444100 AFR_17145 Actinoplanes friuliensis DSM 7358 ROK family protein YP_008734760.1 3707500 R 1246995 CDS YP_008734761.1 556566336 17444101 3708909..3709940 1 NC_022657.1 COG1879 ABC-type sugar transport system, periplasmic component; periplasmic binding protein/LacI transcriptional regulator 3709940 17444101 AFR_17150 Actinoplanes friuliensis DSM 7358 periplasmic binding protein/LacI transcriptional regulator YP_008734761.1 3708909 D 1246995 CDS YP_008734762.1 556566337 17444102 3709937..3710950 1 NC_022657.1 COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components; sugar ABC transporter permease 3710950 17444102 AFR_17155 Actinoplanes friuliensis DSM 7358 sugar ABC transporter permease YP_008734762.1 3709937 D 1246995 CDS YP_008734763.1 556566338 17444103 3710947..3711735 1 NC_022657.1 COG1129 ABC-type sugar transport system, ATPase component; ABC transporter 3711735 17444103 AFR_17160 Actinoplanes friuliensis DSM 7358 ABC transporter YP_008734763.1 3710947 D 1246995 CDS YP_008734764.1 556566339 17444104 3711732..3712382 1 NC_022657.1 COG1072 Panthothenate kinase; fructose transport system kinase 3712382 17444104 AFR_17165 Actinoplanes friuliensis DSM 7358 fructose transport system kinase YP_008734764.1 3711732 D 1246995 CDS YP_008734765.1 556566340 17444105 3712379..3713146 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); dehydrogenase 3713146 17444105 AFR_17170 Actinoplanes friuliensis DSM 7358 dehydrogenase YP_008734765.1 3712379 D 1246995 CDS YP_008734766.1 556566341 17444106 3713140..3714135 1 NC_022657.1 COG1482 Phosphomannose isomerase; mannose-6-phosphate isomerase 3714135 17444106 AFR_17175 Actinoplanes friuliensis DSM 7358 mannose-6-phosphate isomerase YP_008734766.1 3713140 D 1246995 CDS YP_008734767.1 556566342 17444107 3714197..3715135 1 NC_022657.1 hypothetical protein 3715135 17444107 AFR_17180 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734767.1 3714197 D 1246995 CDS YP_008734768.1 556566343 17444108 complement(3715075..3717393) 1 NC_022657.1 COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain; putative signaling protein 3717393 17444108 AFR_17185 Actinoplanes friuliensis DSM 7358 putative signaling protein YP_008734768.1 3715075 R 1246995 CDS YP_008734769.1 556566344 17444109 complement(3717467..3719236) 1 NC_022657.1 COG0642 Signal transduction histidine kinase; histidine kinase 3719236 17444109 AFR_17190 Actinoplanes friuliensis DSM 7358 histidine kinase YP_008734769.1 3717467 R 1246995 CDS YP_008734770.1 556566345 17444110 complement(3719385..3719858) 1 NC_022657.1 COG1714 Predicted membrane protein/domain; hypothetical protein 3719858 17444110 AFR_17195 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734770.1 3719385 R 1246995 CDS YP_008734771.1 556566346 17444111 complement(3719855..3720253) 1 NC_022657.1 hypothetical protein 3720253 17444111 AFR_17200 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734771.1 3719855 R 1246995 CDS YP_008734772.1 556566347 17444112 3720416..3721783 1 NC_022657.1 COG0628 Predicted permease; hypothetical protein 3721783 17444112 AFR_17205 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734772.1 3720416 D 1246995 CDS YP_008734773.1 556566348 17444113 complement(3722350..3722577) 1 NC_022657.1 COG3655 Predicted transcriptional regulator; XRE family transcriptional regulator 3722577 17444113 AFR_17210 Actinoplanes friuliensis DSM 7358 XRE family transcriptional regulator YP_008734773.1 3722350 R 1246995 CDS YP_008734774.1 556566349 17444114 complement(3722577..3723056) 1 NC_022657.1 hypothetical protein 3723056 17444114 AFR_17215 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734774.1 3722577 R 1246995 CDS YP_008734775.1 556566350 17444115 complement(3723106..3723735) 1 NC_022657.1 COG0431 Predicted flavoprotein; NADPH azoreductase 3723735 17444115 AFR_17220 Actinoplanes friuliensis DSM 7358 NADPH azoreductase YP_008734775.1 3723106 R 1246995 CDS YP_008734776.1 556566351 17444116 complement(3723759..3724199) 1 NC_022657.1 COG0784 FOG: CheY-like receiver; putative response regulator receiver domain protein 3724199 17444116 AFR_17225 Actinoplanes friuliensis DSM 7358 putative response regulator receiver domain protein YP_008734776.1 3723759 R 1246995 CDS YP_008734777.1 556566352 17444117 3724288..3725517 1 NC_022657.1 COG2203 FOG: GAF domain; protein serine phosphatase with GAF(s) sensor(s) 3725517 17444117 AFR_17230 Actinoplanes friuliensis DSM 7358 protein serine phosphatase with GAF(s) sensor(s) YP_008734777.1 3724288 D 1246995 CDS YP_008734778.1 556566353 17444118 complement(3725540..3726097) 1 NC_022657.1 hypothetical protein 3726097 17444118 AFR_17235 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734778.1 3725540 R 1246995 CDS YP_008734779.1 556566354 17444119 complement(3726105..3727166) 1 NC_022657.1 COG3940 Predicted beta-xylosidase; glycoside hydrolase family protein 3727166 17444119 AFR_17240 Actinoplanes friuliensis DSM 7358 glycoside hydrolase family protein YP_008734779.1 3726105 R 1246995 CDS YP_008734780.1 556566355 17444120 complement(3727351..3728289) 1 NC_022657.1 COG0642 Signal transduction histidine kinase; anti-sigma regulatory factor (Ser/Thr protein kinase) 3728289 17444120 AFR_17245 Actinoplanes friuliensis DSM 7358 anti-sigma regulatory factor (Ser/Thr protein kinase) YP_008734780.1 3727351 R 1246995 CDS YP_008734781.1 556566356 17444121 complement(3728349..3728756) 1 NC_022657.1 hypothetical protein 3728756 17444121 AFR_17250 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734781.1 3728349 R 1246995 CDS YP_008734782.1 556566357 17444122 3728916..3729617 1 NC_022657.1 COG2124 Cytochrome P450; PEP phosphonomutase-like protein 3729617 17444122 AFR_17255 Actinoplanes friuliensis DSM 7358 PEP phosphonomutase-like protein YP_008734782.1 3728916 D 1246995 CDS YP_008734783.1 556566358 17444123 3729614..3730960 1 NC_022657.1 COG2421 Predicted acetamidase/formamidase; putative acetamidase 3730960 17444123 AFR_17260 Actinoplanes friuliensis DSM 7358 putative acetamidase YP_008734783.1 3729614 D 1246995 CDS YP_008734784.1 556566359 17444124 complement(3730938..3731675) 1 NC_022657.1 COG0730 Predicted permeases; hypothetical protein 3731675 17444124 AFR_17265 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734784.1 3730938 R 1246995 CDS YP_008734785.1 556566360 17444125 complement(3731690..3732826) 1 NC_022657.1 hypothetical protein 3732826 17444125 AFR_17270 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734785.1 3731690 R 1246995 CDS YP_008734786.1 556566361 17444126 complement(3732823..3733713) 1 NC_022657.1 hypothetical protein 3733713 17444126 AFR_17275 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734786.1 3732823 R 1246995 CDS YP_008734787.1 556566362 17444127 complement(3733710..3734777) 1 NC_022657.1 hypothetical protein 3734777 17444127 AFR_17280 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734787.1 3733710 R 1246995 CDS YP_008734788.1 556566363 17444128 3734900..3735514 1 NC_022657.1 hypothetical protein 3735514 17444128 AFR_17285 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734788.1 3734900 D 1246995 CDS YP_008734789.1 556566364 17444129 complement(3735504..3736265) 1 NC_022657.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); alpha/beta hydrolase fold protein 3736265 17444129 AFR_17290 Actinoplanes friuliensis DSM 7358 alpha/beta hydrolase fold protein YP_008734789.1 3735504 R 1246995 CDS YP_008734790.1 556566365 17444130 3736334..3739432 1 NC_022657.1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; ATPase-like protein 3739432 17444130 AFR_17295 Actinoplanes friuliensis DSM 7358 ATPase-like protein YP_008734790.1 3736334 D 1246995 CDS YP_008734791.1 556566366 17444131 3739429..3739863 1 NC_022657.1 hypothetical protein 3739863 17444131 AFR_17300 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734791.1 3739429 D 1246995 CDS YP_008734792.1 556566367 17444132 3739910..3740227 1 NC_022657.1 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); hypothetical protein 3740227 17444132 AFR_17305 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734792.1 3739910 D 1246995 CDS YP_008734793.1 556566368 17444133 3740232..3741194 1 NC_022657.1 COG2207 AraC-type DNA-binding domain-containing proteins; RhaSlike HTH-type transcriptional activator 3741194 17444133 AFR_17310 Actinoplanes friuliensis DSM 7358 RhaSlike HTH-type transcriptional activator YP_008734793.1 3740232 D 1246995 CDS YP_008734794.1 556566369 17444134 complement(3741196..3741855) 1 NC_022657.1 COG0577 ABC-type antimicrobial peptide transport system, permease component; hypothetical protein 3741855 17444134 AFR_17315 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734794.1 3741196 R 1246995 CDS YP_008734795.1 556566370 17444135 complement(3742379..3743035) 1 NC_022657.1 COG1136 ABC-type antimicrobial peptide transport system, ATPase component; hypothetical protein 3743035 17444135 AFR_17320 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734795.1 3742379 R 1246995 CDS YP_008734796.1 556566371 17444136 complement(3743032..3744069) 1 NC_022657.1 COG3409 Putative peptidoglycan-binding domain-containing protein; peptidoglycan-binding domain 1 protein 3744069 17444136 AFR_17325 Actinoplanes friuliensis DSM 7358 peptidoglycan-binding domain 1 protein YP_008734796.1 3743032 R 1246995 CDS YP_008734797.1 556566372 17444137 complement(3744066..3744614) 1 NC_022657.1 hypothetical protein 3744614 17444137 AFR_17330 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734797.1 3744066 R 1246995 CDS YP_008734798.1 556566373 17444138 3744720..3745376 1 NC_022657.1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; two component transcriptional regulator 3745376 17444138 AFR_17335 Actinoplanes friuliensis DSM 7358 two component transcriptional regulator YP_008734798.1 3744720 D 1246995 CDS YP_008734799.1 556566374 17444139 3745373..3746566 1 NC_022657.1 COG0642 Signal transduction histidine kinase; histidine kinase 3746566 17444139 AFR_17340 Actinoplanes friuliensis DSM 7358 histidine kinase YP_008734799.1 3745373 D 1246995 CDS YP_008734800.1 556566375 17444140 3746617..3748914 1 NC_022657.1 COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain; Protein gmr 3748914 17444140 AFR_17345 Actinoplanes friuliensis DSM 7358 Protein gmr YP_008734800.1 3746617 D 1246995 CDS YP_008734801.1 556566376 17444141 complement(3748866..3750002) 1 NC_022657.1 COG0438 Glycosyltransferase; group 1 glycosyl transferase protein 3750002 17444141 AFR_17350 Actinoplanes friuliensis DSM 7358 group 1 glycosyl transferase protein YP_008734801.1 3748866 R 1246995 CDS YP_008734802.1 556566377 17444142 complement(3749999..3750994) 1 NC_022657.1 COG0463 Glycosyltransferases involved in cell wall biogenesis; glucosyl-3-phosphoglycerate synthase 3750994 17444142 AFR_17355 Actinoplanes friuliensis DSM 7358 glucosyl-3-phosphoglycerate synthase YP_008734802.1 3749999 R 1246995 CDS YP_008734803.1 556566378 17444143 3751214..3752140 1 NC_022657.1 COG0673 Predicted dehydrogenases and related proteins; putative oxidoreductase 3752140 17444143 AFR_17360 Actinoplanes friuliensis DSM 7358 putative oxidoreductase YP_008734803.1 3751214 D 1246995 CDS YP_008734804.1 556566379 17444144 3752133..3753209 1 NC_022657.1 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases; putative oxidoreductase 3753209 17444144 AFR_17365 Actinoplanes friuliensis DSM 7358 putative oxidoreductase YP_008734804.1 3752133 D 1246995 CDS YP_008734805.1 556566380 17444145 3753272..3754720 1 NC_022657.1 COG2199 FOG: GGDEF domain; putative signaling protein 3754720 17444145 AFR_17370 Actinoplanes friuliensis DSM 7358 putative signaling protein YP_008734805.1 3753272 D 1246995 CDS YP_008734806.1 556566381 17444146 3754747..3756042 1 NC_022657.1 COG1835 Predicted acyltransferases; acyltransferase 3756042 17444146 AFR_17375 Actinoplanes friuliensis DSM 7358 acyltransferase YP_008734806.1 3754747 D 1246995 CDS YP_008734807.1 556566382 17444147 complement(3755978..3758332) 1 NC_022657.1 COG2199 FOG: GGDEF domain; diguanylate cyclase 3758332 17444147 AFR_17380 Actinoplanes friuliensis DSM 7358 diguanylate cyclase YP_008734807.1 3755978 R 1246995 CDS YP_008734808.1 556566383 17444148 3758433..3758894 1 NC_022657.1 COG2343 Uncharacterized protein conserved in bacteria; hypothetical protein 3758894 17444148 AFR_17385 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734808.1 3758433 D 1246995 CDS YP_008734809.1 556566384 17444149 complement(3758908..3759138) 1 NC_022657.1 hypothetical protein 3759138 17444149 AFR_17390 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734809.1 3758908 R 1246995 CDS YP_008734810.1 556566385 17444150 3759436..3760023 1 NC_022657.1 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; RNA polymerase sigma factor 3760023 17444150 AFR_17395 Actinoplanes friuliensis DSM 7358 RNA polymerase sigma factor YP_008734810.1 3759436 D 1246995 CDS YP_008734811.1 556566386 17444151 3760082..3760579 1 NC_022657.1 hypothetical protein 3760579 17444151 AFR_17400 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734811.1 3760082 D 1246995 CDS YP_008734812.1 556566387 17444152 complement(3760580..3761926) 1 NC_022657.1 COG1404 Subtilisin-like serine proteases; peptidase S8 and S53 subtilisin kexin sedolisin 3761926 17444152 AFR_17405 Actinoplanes friuliensis DSM 7358 peptidase S8 and S53 subtilisin kexin sedolisin YP_008734812.1 3760580 R 1246995 CDS YP_008734813.1 556566388 17444153 3762084..3764582 1 NC_022657.1 hypothetical protein 3764582 17444153 AFR_17410 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734813.1 3762084 D 1246995 CDS YP_008734814.1 556566389 17444154 complement(3764579..3765469) 1 NC_022657.1 hypothetical protein 3765469 17444154 AFR_17415 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734814.1 3764579 R 1246995 CDS YP_008734815.1 556566390 17444155 3767195..3767716 1 NC_022657.1 COG1247 Sortase and related acyltransferases; phosphinothricin acetyltransferase 3767716 17444155 AFR_17420 Actinoplanes friuliensis DSM 7358 phosphinothricin acetyltransferase YP_008734815.1 3767195 D 1246995 CDS YP_008734816.1 556566391 17444156 complement(3767736..3767963) 1 NC_022657.1 hypothetical protein 3767963 17444156 AFR_17425 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734816.1 3767736 R 1246995 CDS YP_008734817.1 556566392 17444157 complement(3767997..3768458) 1 NC_022657.1 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; N-acetyltransferase GCN5 3768458 17444157 AFR_17430 Actinoplanes friuliensis DSM 7358 N-acetyltransferase GCN5 YP_008734817.1 3767997 R 1246995 CDS YP_008734818.1 556566393 17444158 3768547..3769017 1 NC_022657.1 hypothetical protein 3769017 17444158 AFR_17435 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734818.1 3768547 D 1246995 CDS YP_008734819.1 556566394 17444159 complement(3769111..3771210) 1 NC_022657.1 COG3211 Predicted phosphatase; hypothetical protein 3771210 17444159 AFR_17440 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734819.1 3769111 R 1246995 CDS YP_008734820.1 556566395 17444160 3771316..3771828 1 NC_022657.1 hypothetical protein 3771828 17444160 AFR_17445 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734820.1 3771316 D 1246995 CDS YP_008734821.1 556566396 17444161 complement(3771836..3772750) 1 NC_022657.1 COG4977 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain; transcriptional regulator 3772750 17444161 AFR_17450 Actinoplanes friuliensis DSM 7358 transcriptional regulator YP_008734821.1 3771836 R 1246995 CDS YP_008734822.1 556566397 17444162 3772854..3773510 1 NC_022657.1 COG0693 Putative intracellular protease/amidase; ThiJ/PfpI domain-containing protein 3773510 17444162 AFR_17455 Actinoplanes friuliensis DSM 7358 ThiJ/PfpI domain-containing protein YP_008734822.1 3772854 D 1246995 CDS YP_008734823.1 556566398 17444163 3773515..3773829 1 NC_022657.1 hypothetical protein 3773829 17444163 AFR_17460 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734823.1 3773515 D 1246995 CDS YP_008734824.1 556566399 17444164 3773869..3774267 1 NC_022657.1 hypothetical protein 3774267 17444164 AFR_17465 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734824.1 3773869 D 1246995 CDS YP_008734825.1 556566400 17444165 complement(3774264..3774596) 1 NC_022657.1 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); Anti-sigma F factor antagonist 3774596 17444165 AFR_17470 Actinoplanes friuliensis DSM 7358 Anti-sigma F factor antagonist YP_008734825.1 3774264 R 1246995 CDS YP_008734826.1 556566401 17444166 3774724..3776394 1 NC_022657.1 COG0520 Selenocysteine lyase; cysteine desulfurase 3776394 17444166 AFR_17475 Actinoplanes friuliensis DSM 7358 cysteine desulfurase YP_008734826.1 3774724 D 1246995 CDS YP_008734827.1 556566402 17444167 complement(3776265..3777281) 1 NC_022657.1 COG2207 AraC-type DNA-binding domain-containing proteins; AraC-family transcriptional regulator 3777281 17444167 AFR_17480 Actinoplanes friuliensis DSM 7358 AraC-family transcriptional regulator YP_008734827.1 3776265 R 1246995 CDS YP_008734828.1 556566403 17444168 3777365..3778243 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); short-chain oxidoreductase 3778243 17444168 AFR_17485 Actinoplanes friuliensis DSM 7358 short-chain oxidoreductase YP_008734828.1 3777365 D 1246995 CDS YP_008734829.1 556566404 17444169 complement(3778238..3778624) 1 NC_022657.1 hypothetical protein 3778624 17444169 AFR_17490 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734829.1 3778238 R 1246995 CDS YP_008734830.1 556566405 17444170 3778773..3779717 1 NC_022657.1 COG3569 Topoisomerase IB; DNA topoisomerase 3779717 17444170 AFR_17495 Actinoplanes friuliensis DSM 7358 DNA topoisomerase YP_008734830.1 3778773 D 1246995 CDS YP_008734831.1 556566406 17444171 3779714..3780163 1 NC_022657.1 hypothetical protein 3780163 17444171 AFR_17500 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734831.1 3779714 D 1246995 CDS YP_008734832.1 556566407 17444172 3780247..3780921 1 NC_022657.1 hypothetical protein 3780921 17444172 AFR_17505 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734832.1 3780247 D 1246995 CDS YP_008734833.1 556566408 17444173 complement(3780922..3781527) 1 NC_022657.1 COG0655 Multimeric flavodoxin WrbA; NADPH-dependent FMN reductase 3781527 17444173 AFR_17510 Actinoplanes friuliensis DSM 7358 NADPH-dependent FMN reductase YP_008734833.1 3780922 R 1246995 CDS YP_008734834.1 556566409 17444174 3781785..3782495 1 NC_022657.1 COG1191 DNA-directed RNA polymerase specialized sigma subunit; putative RNA polymerase sigma factor 3782495 17444174 AFR_17515 Actinoplanes friuliensis DSM 7358 putative RNA polymerase sigma factor YP_008734834.1 3781785 D 1246995 CDS YP_008734835.1 556566410 17444175 complement(3782574..3784484) 1 NC_022657.1 hypothetical protein 3784484 17444175 AFR_17520 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734835.1 3782574 R 1246995 CDS YP_008734836.1 556566411 17444176 3784734..3785744 1 NC_022657.1 COG1609 Transcriptional regulators; putative LacI-family transcriptional regulator 3785744 17444176 AFR_17525 Actinoplanes friuliensis DSM 7358 putative LacI-family transcriptional regulator YP_008734836.1 3784734 D 1246995 CDS YP_008734837.1 556566412 17444177 complement(3785872..3787203) 1 NC_022657.1 COG0515 Serine/threonine protein kinase; putative serine/threonine protein kinase 3787203 17444177 AFR_17530 Actinoplanes friuliensis DSM 7358 putative serine/threonine protein kinase YP_008734837.1 3785872 R 1246995 CDS YP_008734838.1 556566413 17444178 3787292..3788053 1 NC_022657.1 COG0730 Predicted permeases; hypothetical protein 3788053 17444178 AFR_17535 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734838.1 3787292 D 1246995 CDS YP_008734839.1 556566414 17444179 3788175..3788714 1 NC_022657.1 Ricin B lectin 3788714 17444179 AFR_17540 Actinoplanes friuliensis DSM 7358 Ricin B lectin YP_008734839.1 3788175 D 1246995 CDS YP_008734840.1 556566415 17444180 3788732..3790279 1 NC_022657.1 Esterase 3790279 17444180 AFR_17545 Actinoplanes friuliensis DSM 7358 Esterase YP_008734840.1 3788732 D 1246995 CDS YP_008734841.1 556566416 17444181 complement(3790328..3791932) 1 NC_022657.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); putative tripeptidylaminopeptidase 3791932 17444181 AFR_17550 Actinoplanes friuliensis DSM 7358 putative tripeptidylaminopeptidase YP_008734841.1 3790328 R 1246995 CDS YP_008734842.1 556566417 17444182 3792184..3793257 1 NC_022657.1 peptidase m23 3793257 17444182 AFR_17555 Actinoplanes friuliensis DSM 7358 peptidase m23 YP_008734842.1 3792184 D 1246995 CDS YP_008734843.1 556566418 17444183 3793355..3794143 1 NC_022657.1 COG1396 Predicted transcriptional regulators; XRE family transcriptional regulator 3794143 17444183 AFR_17560 Actinoplanes friuliensis DSM 7358 XRE family transcriptional regulator YP_008734843.1 3793355 D 1246995 CDS YP_008734844.1 556566419 17444184 3794488..3795633 1 NC_022657.1 COG4677 Pectin methylesterase; putative pectinesterase 3795633 17444184 AFR_17565 Actinoplanes friuliensis DSM 7358 putative pectinesterase YP_008734844.1 3794488 D 1246995 CDS YP_008734845.1 556566420 17444185 complement(3795619..3796518) 1 NC_022657.1 COG0119 Isopropylmalate/homocitrate/citramalate synthases; hydroxymethylglutaryl-CoA lyase 3796518 17444185 AFR_17570 Actinoplanes friuliensis DSM 7358 hydroxymethylglutaryl-CoA lyase YP_008734845.1 3795619 R 1246995 CDS YP_008734846.1 556566421 17444186 3796682..3797266 1 NC_022657.1 COG1802 Transcriptional regulators; GntR family transcriptional regulator 3797266 17444186 AFR_17575 Actinoplanes friuliensis DSM 7358 GntR family transcriptional regulator YP_008734846.1 3796682 D 1246995 CDS YP_008734847.1 556566422 17444187 3797263..3798456 1 NC_022657.1 COG1804 Predicted acyl-CoA transferases/carnitine dehydratase; succinyl-CoA:(R)-citramalate CoA-transferase 3798456 17444187 AFR_17580 Actinoplanes friuliensis DSM 7358 succinyl-CoA:(R)-citramalate CoA-transferase YP_008734847.1 3797263 D 1246995 CDS YP_008734848.1 556566423 17444188 3798493..3800529 1 NC_022657.1 COG0145 N-methylhydantoinase A/acetone carboxylase, beta subunit; hydantoinase/oxoprolinase 3800529 17444188 AFR_17585 Actinoplanes friuliensis DSM 7358 hydantoinase/oxoprolinase YP_008734848.1 3798493 D 1246995 CDS YP_008734849.1 556566424 17444189 3800531..3802402 1 NC_022657.1 COG0146 N-methylhydantoinase B/acetone carboxylase, alpha subunit; 5-oxoprolinase 3802402 17444189 AFR_17590 Actinoplanes friuliensis DSM 7358 5-oxoprolinase YP_008734849.1 3800531 D 1246995 CDS YP_008734850.1 556566425 17444190 3802351..3803013 1 NC_022657.1 COG1335 Amidases related to nicotinamidase; isochorismatase hydrolase 3803013 17444190 AFR_17595 Actinoplanes friuliensis DSM 7358 isochorismatase hydrolase YP_008734850.1 3802351 D 1246995 CDS YP_008734851.1 556566426 17444191 complement(3802988..3805822) 1 NC_022657.1 COG1472 Beta-glucosidase-related glycosidases; putative glycosyl hydrolase 3805822 17444191 AFR_17600 Actinoplanes friuliensis DSM 7358 putative glycosyl hydrolase YP_008734851.1 3802988 R 1246995 CDS YP_008734852.1 556566427 17444192 complement(3805980..3807206) 1 NC_022657.1 COG1940 Transcriptional regulator/sugar kinase; rok family protein 3807206 17444192 AFR_17605 Actinoplanes friuliensis DSM 7358 rok family protein YP_008734852.1 3805980 R 1246995 CDS YP_008734853.1 556566428 17444193 3807389..3809065 1 NC_022657.1 COG1653 ABC-type sugar transport system, periplasmic component; family 1 extracellular solute-binding protein 3809065 17444193 AFR_17610 Actinoplanes friuliensis DSM 7358 family 1 extracellular solute-binding protein YP_008734853.1 3807389 D 1246995 CDS YP_008734854.1 556566429 17444194 3809062..3810087 1 NC_022657.1 COG4209 ABC-type polysaccharide transport system, permease component; binding-protein-dependent transport systems inner membrane component 3810087 17444194 AFR_17615 Actinoplanes friuliensis DSM 7358 binding-protein-dependent transport systems inner membrane component YP_008734854.1 3809062 D 1246995 CDS YP_008734855.1 556566430 17444195 3810084..3810998 1 NC_022657.1 COG0395 ABC-type sugar transport system, permease component; binding-protein-dependent transport systems inner membrane component 3810998 17444195 AFR_17620 Actinoplanes friuliensis DSM 7358 binding-protein-dependent transport systems inner membrane component YP_008734855.1 3810084 D 1246995 CDS YP_008734856.1 556566431 17444196 complement(3810988..3813057) 1 NC_022657.1 hypothetical protein 3813057 17444196 AFR_17625 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734856.1 3810988 R 1246995 CDS YP_008734857.1 556566432 17444197 3813098..3815032 1 NC_022657.1 COG1874 Beta-galactosidase; beta-galactosidase 3815032 17444197 AFR_17630 Actinoplanes friuliensis DSM 7358 beta-galactosidase YP_008734857.1 3813098 D 1246995 CDS YP_008734858.1 556566433 17444198 3815148..3815465 1 NC_022657.1 hypothetical protein 3815465 17444198 AFR_17635 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734858.1 3815148 D 1246995 CDS YP_008734859.1 556566434 17444199 complement(3815455..3815967) 1 NC_022657.1 COG2203 FOG: GAF domain; putative GAF sensor protein 3815967 17444199 AFR_17640 Actinoplanes friuliensis DSM 7358 putative GAF sensor protein YP_008734859.1 3815455 R 1246995 CDS YP_008734860.1 556566435 17444200 complement(3816029..3817924) 1 NC_022657.1 COG3693 Beta-1,4-xylanase; putative glycosyl hydrolase 3817924 17444200 AFR_17645 Actinoplanes friuliensis DSM 7358 putative glycosyl hydrolase YP_008734860.1 3816029 R 1246995 CDS YP_008734861.1 556566436 17444201 complement(3817963..3818583) 1 NC_022657.1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; LuxR family two component transcriptional regulator 3818583 17444201 AFR_17650 Actinoplanes friuliensis DSM 7358 LuxR family two component transcriptional regulator YP_008734861.1 3817963 R 1246995 CDS YP_008734862.1 556566437 17444202 complement(3818580..3819695) 1 NC_022657.1 COG4585 Signal transduction histidine kinase; integral membrane sensor signal transduction histidine kinase 3819695 17444202 AFR_17655 Actinoplanes friuliensis DSM 7358 integral membrane sensor signal transduction histidine kinase YP_008734862.1 3818580 R 1246995 CDS YP_008734863.1 556566438 17444203 3819804..3820562 1 NC_022657.1 hypothetical protein 3820562 17444203 AFR_17660 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734863.1 3819804 D 1246995 CDS YP_008734864.1 556566439 17444204 3820753..3820980 1 NC_022657.1 hypothetical protein 3820980 17444204 AFR_17665 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734864.1 3820753 D 1246995 CDS YP_008734865.1 556566440 17444205 3820977..3823544 1 NC_022657.1 hypothetical protein 3823544 17444205 AFR_17670 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734865.1 3820977 D 1246995 CDS YP_008734866.1 556566441 17444206 complement(3823541..3824563) 1 NC_022657.1 COG0258 5'-3' exonuclease (including N-terminal domain of PolI); DNA polymerase I 3824563 17444206 AFR_17675 Actinoplanes friuliensis DSM 7358 DNA polymerase I YP_008734866.1 3823541 R 1246995 CDS YP_008734867.1 556566442 17444207 complement(3824573..3825529) 1 NC_022657.1 COG2378 Predicted transcriptional regulator; DeoR family transcriptional regulator 3825529 17444207 AFR_17680 Actinoplanes friuliensis DSM 7358 DeoR family transcriptional regulator YP_008734867.1 3824573 R 1246995 CDS YP_008734868.1 556566443 17444208 3825618..3826067 1 NC_022657.1 glyoxalase/bleomycin resistance protein/dioxygenase 3826067 17444208 AFR_17685 Actinoplanes friuliensis DSM 7358 glyoxalase/bleomycin resistance protein/dioxygenase YP_008734868.1 3825618 D 1246995 CDS YP_008734869.1 556566444 17444209 complement(3826007..3827404) 1 NC_022657.1 COG0001 Glutamate-1-semialdehyde aminotransferase; aminotransferase 3827404 17444209 AFR_17690 Actinoplanes friuliensis DSM 7358 aminotransferase YP_008734869.1 3826007 R 1246995 CDS YP_008734870.1 556566445 17444210 3827651..3828073 1 NC_022657.1 hypothetical protein 3828073 17444210 AFR_17695 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734870.1 3827651 D 1246995 CDS YP_008734871.1 556566446 17444211 3828231..3829070 1 NC_022657.1 COG3191 L-aminopeptidase/D-esterase; hypothetical protein 3829070 17444211 AFR_17700 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734871.1 3828231 D 1246995 CDS YP_008734872.1 556566447 17444212 complement(3830190..3831239) 1 NC_022657.1 hypothetical protein 3831239 17444212 AFR_17705 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734872.1 3830190 R 1246995 CDS YP_008734873.1 556566448 17444213 complement(3831236..3831760) 1 NC_022657.1 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; ECF subfamily RNA polymerase sigma-24 subunit 3831760 17444213 AFR_17710 Actinoplanes friuliensis DSM 7358 ECF subfamily RNA polymerase sigma-24 subunit YP_008734873.1 3831236 R 1246995 CDS YP_008734874.1 556566449 17444214 3832191..3834161 1 NC_022657.1 COG3693 Beta-1,4-xylanase; endo-1,4-beta-xylanase 3834161 17444214 AFR_17715 Actinoplanes friuliensis DSM 7358 endo-1,4-beta-xylanase YP_008734874.1 3832191 D 1246995 CDS YP_008734875.1 556566450 17444215 complement(3834225..3835850) 1 NC_022657.1 COG1574 Predicted metal-dependent hydrolase with the TIM-barrel fold; putative amidohydrolase 3835850 17444215 AFR_17720 Actinoplanes friuliensis DSM 7358 putative amidohydrolase YP_008734875.1 3834225 R 1246995 CDS YP_008734876.1 556566451 17444216 complement(3835863..3836939) 1 NC_022657.1 hypothetical protein 3836939 17444216 AFR_17725 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734876.1 3835863 R 1246995 CDS YP_008734877.1 556566452 17444217 3837084..3838373 1 NC_022657.1 phosphoesterase, PA-phosphatase-like protein 3838373 17444217 AFR_17730 Actinoplanes friuliensis DSM 7358 phosphoesterase, PA-phosphatase-like protein YP_008734877.1 3837084 D 1246995 CDS YP_008734878.1 556566453 17444218 3838383..3838661 1 NC_022657.1 hypothetical protein 3838661 17444218 AFR_17735 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734878.1 3838383 D 1246995 CDS YP_008734879.1 556566454 17444219 complement(3838669..3839127) 1 NC_022657.1 COG2258 Uncharacterized protein conserved in bacteria; hypothetical protein 3839127 17444219 AFR_17740 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734879.1 3838669 R 1246995 CDS YP_008734880.1 556566455 17444220 complement(3839142..3839585) 1 NC_022657.1 COG0784 FOG: CheY-like receiver; two-component system response regulator 3839585 17444220 AFR_17745 Actinoplanes friuliensis DSM 7358 two-component system response regulator YP_008734880.1 3839142 R 1246995 CDS YP_008734881.1 556566456 17444221 complement(3839608..3840537) 1 NC_022657.1 COG1619 Uncharacterized proteins, homologs of microcin C7 resistance protein MccF; peptidase U61, LD-carboxypeptidase A 3840537 17444221 AFR_17750 Actinoplanes friuliensis DSM 7358 peptidase U61, LD-carboxypeptidase A YP_008734881.1 3839608 R 1246995 CDS YP_008734882.1 556566457 17444222 3840594..3841571 1 NC_022657.1 hypothetical protein 3841571 17444222 AFR_17755 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734882.1 3840594 D 1246995 CDS YP_008734883.1 556566458 17444223 complement(3841555..3842289) 1 NC_022657.1 COG0639 Diadenosine tetraphosphatase and related serine/threonine protein phosphatases; putative serine/threonine protein phosphatase 3842289 17444223 AFR_17760 Actinoplanes friuliensis DSM 7358 putative serine/threonine protein phosphatase YP_008734883.1 3841555 R 1246995 CDS YP_008734884.1 556566459 17444224 complement(3842862..3843485) 1 NC_022657.1 hypothetical protein 3843485 17444224 AFR_17765 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734884.1 3842862 R 1246995 CDS YP_008734885.1 556566460 17444225 complement(3843496..3843822) 1 NC_022657.1 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); putative anti-sigma factor antagonist 3843822 17444225 AFR_17770 Actinoplanes friuliensis DSM 7358 putative anti-sigma factor antagonist YP_008734885.1 3843496 R 1246995 CDS YP_008734886.1 556566461 17444226 3843930..3844505 1 NC_022657.1 COG0262 Dihydrofolate reductase; hypothetical protein 3844505 17444226 AFR_17775 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734886.1 3843930 D 1246995 CDS YP_008734887.1 556566462 17444227 complement(3844493..3845881) 1 NC_022657.1 COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes; pyridine nucleotide-disulfide oxidoreductase dimerization subunit 3845881 17444227 AFR_17780 Actinoplanes friuliensis DSM 7358 pyridine nucleotide-disulfide oxidoreductase dimerization subunit YP_008734887.1 3844493 R 1246995 CDS YP_008734888.1 556566463 17444228 3846078..3846962 1 NC_022657.1 COG0158 Fructose-1,6-bisphosphatase; putative DNA-binding protein 3846962 17444228 AFR_17785 Actinoplanes friuliensis DSM 7358 putative DNA-binding protein YP_008734888.1 3846078 D 1246995 CDS YP_008734889.1 556566464 17444229 3847135..3847389 1 NC_022657.1 hypothetical protein 3847389 17444229 AFR_17790 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734889.1 3847135 D 1246995 CDS YP_008734890.1 556566465 17444230 complement(3847386..3848303) 1 NC_022657.1 COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; Membrane-bound lytic murein transglycosylase F 3848303 17444230 AFR_17795 Actinoplanes friuliensis DSM 7358 Membrane-bound lytic murein transglycosylase F YP_008734890.1 3847386 R 1246995 CDS YP_008734891.1 556566466 17444231 complement(3848300..3850327) 1 NC_022657.1 COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain; Phytochrome-like protein cph2 3850327 17444231 AFR_17800 Actinoplanes friuliensis DSM 7358 Phytochrome-like protein cph2 YP_008734891.1 3848300 R 1246995 CDS YP_008734892.1 556566467 17444232 3850520..3852130 1 NC_022657.1 COG2072 Predicted flavoprotein involved in K+ transport; FAD dependent oxidoreductase 3852130 17444232 AFR_17805 Actinoplanes friuliensis DSM 7358 FAD dependent oxidoreductase YP_008734892.1 3850520 D 1246995 CDS YP_008734893.1 556566468 17444233 3852156..3853106 1 NC_022657.1 COG0657 Esterase/lipase; Lipase LipH 3853106 17444233 AFR_17810 Actinoplanes friuliensis DSM 7358 Lipase LipH YP_008734893.1 3852156 D 1246995 CDS YP_008734894.1 556566469 17444234 3853185..3853448 1 NC_022657.1 hypothetical protein 3853448 17444234 AFR_17815 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734894.1 3853185 D 1246995 CDS YP_008734895.1 556566470 17444235 complement(3853503..3854474) 1 NC_022657.1 hypothetical protein 3854474 17444235 AFR_17820 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734895.1 3853503 R 1246995 CDS YP_008734896.1 556566471 17444236 3854765..3855532 1 NC_022657.1 arabinofuranosidase 3855532 17444236 AFR_17825 Actinoplanes friuliensis DSM 7358 arabinofuranosidase YP_008734896.1 3854765 D 1246995 CDS YP_008734897.1 556566472 17444237 complement(3855529..3856302) 1 NC_022657.1 COG4312 Uncharacterized protein conserved in bacteria; hypothetical protein 3856302 17444237 AFR_17830 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734897.1 3855529 R 1246995 CDS YP_008734898.1 556566473 17444238 3856665..3858338 1 NC_022657.1 COG2304 Uncharacterized protein containing a von Willebrand factor type A (vWA) domain; von willebrand factor type a 3858338 17444238 AFR_17835 Actinoplanes friuliensis DSM 7358 von willebrand factor type a YP_008734898.1 3856665 D 1246995 CDS YP_008734899.1 556566474 17444239 3858423..3859133 1 NC_022657.1 COG0652 Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family; cyclophilin type peptidyl-prolyl cis-trans isomerase 3859133 17444239 AFR_17840 Actinoplanes friuliensis DSM 7358 cyclophilin type peptidyl-prolyl cis-trans isomerase YP_008734899.1 3858423 D 1246995 CDS YP_008734900.1 556566475 17444240 3859250..3859474 1 NC_022657.1 hypothetical protein 3859474 17444240 AFR_17845 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734900.1 3859250 D 1246995 CDS YP_008734901.1 556566476 17444241 complement(3859478..3860242) 1 NC_022657.1 COG0500 SAM-dependent methyltransferases; putative methyltransferase 3860242 17444241 AFR_17850 Actinoplanes friuliensis DSM 7358 putative methyltransferase YP_008734901.1 3859478 R 1246995 CDS YP_008734902.1 556566477 17444242 complement(3860257..3861174) 1 NC_022657.1 COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily; hypothetical protein 3861174 17444242 AFR_17855 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734902.1 3860257 R 1246995 CDS YP_008734903.1 556566478 17444243 3861256..3862146 1 NC_022657.1 COG0583 Transcriptional regulator; LysR family transcriptional regulator 3862146 17444243 AFR_17860 Actinoplanes friuliensis DSM 7358 LysR family transcriptional regulator YP_008734903.1 3861256 D 1246995 CDS YP_008734904.1 556566479 17444244 complement(3862136..3863596) 1 NC_022657.1 COG3940 Predicted beta-xylosidase; putative glycosyl hydrolase 3863596 17444244 AFR_17865 Actinoplanes friuliensis DSM 7358 putative glycosyl hydrolase YP_008734904.1 3862136 R 1246995 CDS YP_008734905.1 556566480 17444245 3863776..3864798 1 NC_022657.1 COG3507 Beta-xylosidase; putative glycosyl hydrolase 3864798 17444245 AFR_17870 Actinoplanes friuliensis DSM 7358 putative glycosyl hydrolase YP_008734905.1 3863776 D 1246995 CDS YP_008734906.1 556566481 17444246 3864968..3865951 1 NC_022657.1 COG3866 Pectate lyase; putative pectate lyase 3865951 17444246 AFR_17875 Actinoplanes friuliensis DSM 7358 putative pectate lyase YP_008734906.1 3864968 D 1246995 CDS YP_008734907.1 556566482 17444247 complement(3867534..3868649) 1 NC_022657.1 COG3397 Uncharacterized protein conserved in bacteria; putative cellulose/chitin-binding protein 3868649 17444247 AFR_17880 Actinoplanes friuliensis DSM 7358 putative cellulose/chitin-binding protein YP_008734907.1 3867534 R 1246995 CDS YP_008734908.1 556566483 17444248 3868814..3869203 1 NC_022657.1 COG0346 Lactoylglutathione lyase and related lyases; glyoxalase/bleomycin resistance protein/dioxygenase 3869203 17444248 AFR_17885 Actinoplanes friuliensis DSM 7358 glyoxalase/bleomycin resistance protein/dioxygenase YP_008734908.1 3868814 D 1246995 CDS YP_008734909.1 556566484 17444249 3869442..3869987 1 NC_022657.1 hypothetical protein 3869987 17444249 AFR_17890 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734909.1 3869442 D 1246995 CDS YP_008734910.1 556566485 17444250 3870041..3870628 1 NC_022657.1 hypothetical protein 3870628 17444250 AFR_17895 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734910.1 3870041 D 1246995 CDS YP_008734911.1 556566486 17444251 3870638..3871366 1 NC_022657.1 COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase; 1-acyl-sn-glycerol-3-phosphate acyltransferase 3871366 17444251 AFR_17900 Actinoplanes friuliensis DSM 7358 1-acyl-sn-glycerol-3-phosphate acyltransferase YP_008734911.1 3870638 D 1246995 CDS YP_008734912.1 556566487 17444252 3871363..3872520 1 NC_022657.1 COG0438 Glycosyltransferase; group 1 glycosyl transferase 3872520 17444252 AFR_17905 Actinoplanes friuliensis DSM 7358 group 1 glycosyl transferase YP_008734912.1 3871363 D 1246995 CDS YP_008734913.1 556566488 17444253 complement(3872490..3873173) 1 NC_022657.1 COG1802 Transcriptional regulators; GntR family transcriptional regulator 3873173 17444253 AFR_17910 Actinoplanes friuliensis DSM 7358 GntR family transcriptional regulator YP_008734913.1 3872490 R 1246995 CDS YP_008734914.1 556566489 17444254 3873211..3875988 1 NC_022657.1 COG0277 FAD/FMN-containing dehydrogenases; putative oxidoreductase 3875988 17444254 AFR_17915 Actinoplanes friuliensis DSM 7358 putative oxidoreductase YP_008734914.1 3873211 D 1246995 CDS YP_008734915.1 556566490 17444255 3876036..3876428 1 NC_022657.1 COG1733 Predicted transcriptional regulators; DNA-binding protein 3876428 17444255 AFR_17920 Actinoplanes friuliensis DSM 7358 DNA-binding protein YP_008734915.1 3876036 D 1246995 CDS YP_008734916.1 556566491 17444256 complement(3876403..3877056) 1 NC_022657.1 COG1182 Acyl carrier protein phosphodiesterase; FMN-dependent NADH-azoreductase 3877056 17444256 AFR_17925 Actinoplanes friuliensis DSM 7358 FMN-dependent NADH-azoreductase YP_008734916.1 3876403 R 1246995 CDS YP_008734917.1 556566492 17444257 3877169..3877642 1 NC_022657.1 COG0583 Transcriptional regulator; LysR family transcriptional regulator 3877642 17444257 AFR_17930 Actinoplanes friuliensis DSM 7358 LysR family transcriptional regulator YP_008734917.1 3877169 D 1246995 CDS YP_008734918.1 556566493 17444258 3877736..3878431 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); hypothetical protein 3878431 17444258 AFR_17935 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734918.1 3877736 D 1246995 CDS YP_008734919.1 556566494 17444259 3878464..3879345 1 NC_022657.1 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases; putative luciferase-like monooxygenase 3879345 17444259 AFR_17940 Actinoplanes friuliensis DSM 7358 putative luciferase-like monooxygenase YP_008734919.1 3878464 D 1246995 CDS YP_008734920.1 556566495 17444260 complement(3879347..3880081) 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); short-chain dehydrogenase/reductase SDR 3880081 17444260 AFR_17945 Actinoplanes friuliensis DSM 7358 short-chain dehydrogenase/reductase SDR YP_008734920.1 3879347 R 1246995 CDS YP_008734921.1 556566496 17444261 3880120..3880917 1 NC_022657.1 COG1396 Predicted transcriptional regulators; helix-turn-helix domain-containing protein 3880917 17444261 AFR_17950 Actinoplanes friuliensis DSM 7358 helix-turn-helix domain-containing protein YP_008734921.1 3880120 D 1246995 CDS YP_008734922.1 556566497 17444262 complement(3880906..3882963) 1 NC_022657.1 COG0438 Glycosyltransferase; transferase 3882963 17444262 AFR_17955 Actinoplanes friuliensis DSM 7358 transferase YP_008734922.1 3880906 R 1246995 CDS YP_008734923.1 556566498 17444263 complement(3882965..3884509) 1 NC_022657.1 UDP-N-acetylglucosamine--lysosomal-enzyme N-acetylglucosamine phosphotransferase 3884509 17444263 AFR_17960 Actinoplanes friuliensis DSM 7358 UDP-N-acetylglucosamine--lysosomal-enzyme N-acetylglucosamine phosphotransferase YP_008734923.1 3882965 R 1246995 CDS YP_008734924.1 556566499 17444264 complement(3884502..3886295) 1 NC_022657.1 hypothetical protein 3886295 17444264 AFR_17965 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734924.1 3884502 R 1246995 CDS YP_008734925.1 556566500 17444265 3886802..3887107 1 NC_022657.1 lipoprotein 3887107 17444265 AFR_17970 Actinoplanes friuliensis DSM 7358 lipoprotein YP_008734925.1 3886802 D 1246995 CDS YP_008734926.1 556566501 17444266 3887146..3887712 1 NC_022657.1 hypothetical protein 3887712 17444266 AFR_17975 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734926.1 3887146 D 1246995 CDS YP_008734927.1 556566502 17444267 complement(3887762..3890137) 1 NC_022657.1 COG1472 Beta-glucosidase-related glycosidases; beta-glucosidase 3890137 17444267 AFR_17980 Actinoplanes friuliensis DSM 7358 beta-glucosidase YP_008734927.1 3887762 R 1246995 CDS YP_008734928.1 556566503 17444268 3890459..3891796 1 NC_022657.1 COG1653 ABC-type sugar transport system, periplasmic component; family 1 extracellular solute-binding protein 3891796 17444268 AFR_17985 Actinoplanes friuliensis DSM 7358 family 1 extracellular solute-binding protein YP_008734928.1 3890459 D 1246995 CDS YP_008734929.1 556566504 17444269 3891793..3892719 1 NC_022657.1 COG1175 ABC-type sugar transport systems, permease components; binding-protein-dependent transport protein 3892719 17444269 AFR_17990 Actinoplanes friuliensis DSM 7358 binding-protein-dependent transport protein YP_008734929.1 3891793 D 1246995 CDS YP_008734930.1 556566505 17444270 3892719..3893627 1 NC_022657.1 COG0395 ABC-type sugar transport system, permease component; carbohydrate ABC transporter membrane protein 3893627 17444270 AFR_17995 Actinoplanes friuliensis DSM 7358 carbohydrate ABC transporter membrane protein YP_008734930.1 3892719 D 1246995 CDS YP_008734931.1 556566506 17444271 complement(3893596..3894642) 1 NC_022657.1 COG1609 Transcriptional regulators; putative LacI-family transcriptional regulator 3894642 17444271 AFR_18000 Actinoplanes friuliensis DSM 7358 putative LacI-family transcriptional regulator YP_008734931.1 3893596 R 1246995 CDS YP_008734932.1 556566507 17444272 complement(3894721..3895803) 1 NC_022657.1 COG3693 Beta-1,4-xylanase; endo-1,4-beta-xylanase 3895803 17444272 AFR_18005 Actinoplanes friuliensis DSM 7358 endo-1,4-beta-xylanase YP_008734932.1 3894721 R 1246995 CDS YP_008734933.1 556566508 17444273 3896078..3897361 1 NC_022657.1 COG2755 Lysophospholipase L1 and related esterases; G-D-S-L family lipolytic protein 3897361 17444273 AFR_18010 Actinoplanes friuliensis DSM 7358 G-D-S-L family lipolytic protein YP_008734933.1 3896078 D 1246995 CDS YP_008734934.1 556566509 17444274 3897379..3900333 1 NC_022657.1 hypothetical protein 3900333 17444274 AFR_18015 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734934.1 3897379 D 1246995 CDS YP_008734935.1 556566510 17444275 3900330..3901547 1 NC_022657.1 COG2755 Lysophospholipase L1 and related esterases; SGNH hydrolase 3901547 17444275 AFR_18020 Actinoplanes friuliensis DSM 7358 SGNH hydrolase YP_008734935.1 3900330 D 1246995 CDS YP_008734936.1 556566511 17444276 3901544..3902056 1 NC_022657.1 COG4977 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain; Transcriptional regulator, AraC family protein 3902056 17444276 AFR_18025 Actinoplanes friuliensis DSM 7358 Transcriptional regulator, AraC family protein YP_008734936.1 3901544 D 1246995 CDS YP_008734937.1 556566512 17444277 3902128..3903519 1 NC_022657.1 COG3693 Beta-1,4-xylanase; endo-1,4-beta-xylanase 3903519 17444277 AFR_18030 Actinoplanes friuliensis DSM 7358 endo-1,4-beta-xylanase YP_008734937.1 3902128 D 1246995 CDS YP_008734938.1 556566513 17444278 3903516..3904814 1 NC_022657.1 COG3509 Poly(3-hydroxybutyrate) depolymerase; esterase, PHB depolymerase family protein 3904814 17444278 AFR_18035 Actinoplanes friuliensis DSM 7358 esterase, PHB depolymerase family protein YP_008734938.1 3903516 D 1246995 CDS YP_008734939.1 556566514 17444279 complement(3904870..3906636) 1 NC_022657.1 COG2304 Uncharacterized protein containing a von Willebrand factor type A (vWA) domain; hypothetical protein 3906636 17444279 AFR_18040 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734939.1 3904870 R 1246995 CDS YP_008734940.1 556566515 17444280 3906849..3908969 1 NC_022657.1 COG0272 NAD-dependent DNA ligase (contains BRCT domain type II); DNA ligase 3908969 17444280 AFR_18045 Actinoplanes friuliensis DSM 7358 DNA ligase YP_008734940.1 3906849 D 1246995 CDS YP_008734941.1 556566516 17444281 complement(3909000..3909560) 1 NC_022657.1 COG0262 Dihydrofolate reductase; bifunctional pyrimidine deaminase/reductase-like protein 3909560 17444281 AFR_18050 Actinoplanes friuliensis DSM 7358 bifunctional pyrimidine deaminase/reductase-like protein YP_008734941.1 3909000 R 1246995 CDS YP_008734942.1 556566517 17444282 3909794..3910981 1 NC_022657.1 hypothetical protein 3910981 17444282 AFR_18055 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734942.1 3909794 D 1246995 CDS YP_008734943.1 556566518 17444283 3910991..3912028 1 NC_022657.1 COG0226 ABC-type phosphate transport system, periplasmic component; putative phosphate ABC transporter substrate-binding protein 3912028 17444283 AFR_18060 Actinoplanes friuliensis DSM 7358 putative phosphate ABC transporter substrate-binding protein YP_008734943.1 3910991 D 1246995 CDS YP_008734944.1 556566519 17444284 3912038..3913093 1 NC_022657.1 COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases); aldo/keto reductase 3913093 17444284 AFR_18065 Actinoplanes friuliensis DSM 7358 aldo/keto reductase YP_008734944.1 3912038 D 1246995 CDS YP_008734945.1 556566520 17444285 3913104..3913682 1 NC_022657.1 COG1309 Transcriptional regulator; putative TetR-family transcriptional regulator 3913682 17444285 AFR_18070 Actinoplanes friuliensis DSM 7358 putative TetR-family transcriptional regulator YP_008734945.1 3913104 D 1246995 CDS YP_008734946.1 556566521 17444286 complement(3913679..3914458) 1 NC_022657.1 COG0842 ABC-type multidrug transport system, permease component; ABC transporter 3914458 17444286 AFR_18075 Actinoplanes friuliensis DSM 7358 ABC transporter YP_008734946.1 3913679 R 1246995 CDS YP_008734947.1 556566522 17444287 complement(3914455..3915384) 1 NC_022657.1 COG1131 ABC-type multidrug transport system, ATPase component; daunorubicin resistance ABC transporter ATPase subunit 3915384 17444287 AFR_18080 Actinoplanes friuliensis DSM 7358 daunorubicin resistance ABC transporter ATPase subunit YP_008734947.1 3914455 R 1246995 CDS YP_008734948.1 556566523 17444288 3915543..3916298 1 NC_022657.1 COG1309 Transcriptional regulator; TetR family transcriptional regulator 3916298 17444288 AFR_18085 Actinoplanes friuliensis DSM 7358 TetR family transcriptional regulator YP_008734948.1 3915543 D 1246995 CDS YP_008734949.1 556566524 17444289 3916358..3917746 1 NC_022657.1 peptidase S37 tripeptidyl aminopeptidase 3917746 17444289 AFR_18090 Actinoplanes friuliensis DSM 7358 peptidase S37 tripeptidyl aminopeptidase YP_008734949.1 3916358 D 1246995 CDS YP_008734950.1 556566525 17444290 3917756..3920707 1 NC_022657.1 hypothetical protein 3920707 17444290 AFR_18095 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734950.1 3917756 D 1246995 CDS YP_008734951.1 556566526 17444291 3920682..3921524 1 NC_022657.1 COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases); aldo/keto reductase 3921524 17444291 AFR_18100 Actinoplanes friuliensis DSM 7358 aldo/keto reductase YP_008734951.1 3920682 D 1246995 CDS YP_008734952.1 556566527 17444292 complement(3921493..3921861) 1 NC_022657.1 hypothetical protein 3921861 17444292 AFR_18105 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734952.1 3921493 R 1246995 CDS YP_008734953.1 556566528 17444293 complement(3921864..3923672) 1 NC_022657.1 COG0515 Serine/threonine protein kinase; Serine/threonine protein kinase 3923672 17444293 AFR_18110 Actinoplanes friuliensis DSM 7358 Serine/threonine protein kinase YP_008734953.1 3921864 R 1246995 CDS YP_008734954.1 556566529 17444294 complement(3923899..3924399) 1 NC_022657.1 nucleoside-diphosphate-sugar epimerase 3924399 17444294 AFR_18115 Actinoplanes friuliensis DSM 7358 nucleoside-diphosphate-sugar epimerase YP_008734954.1 3923899 R 1246995 CDS YP_008734955.1 556566530 17444295 complement(3924409..3925161) 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); short-chain dehydrogenase/reductase SDR 3925161 17444295 AFR_18120 Actinoplanes friuliensis DSM 7358 short-chain dehydrogenase/reductase SDR YP_008734955.1 3924409 R 1246995 CDS YP_008734956.1 556566531 17444296 3925245..3925892 1 NC_022657.1 COG1309 Transcriptional regulator; TetR family transcriptional regulator 3925892 17444296 AFR_18125 Actinoplanes friuliensis DSM 7358 TetR family transcriptional regulator YP_008734956.1 3925245 D 1246995 CDS YP_008734957.1 556566532 17444297 complement(3926478..3929027) 1 NC_022657.1 secreted protein 3929027 17444297 AFR_18130 Actinoplanes friuliensis DSM 7358 secreted protein YP_008734957.1 3926478 R 1246995 CDS YP_008734958.1 556566533 17444298 complement(3929101..3931056) 1 NC_022657.1 COG4934 Predicted protease; serine protease 3931056 17444298 AFR_18135 Actinoplanes friuliensis DSM 7358 serine protease YP_008734958.1 3929101 R 1246995 CDS YP_008734959.1 556566534 17444299 3931208..3933406 1 NC_022657.1 COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain; putative signaling protein 3933406 17444299 AFR_18140 Actinoplanes friuliensis DSM 7358 putative signaling protein YP_008734959.1 3931208 D 1246995 CDS YP_008734960.1 556566535 17444300 3933417..3934295 1 NC_022657.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); alpha/beta hydrolase 3934295 17444300 AFR_18145 Actinoplanes friuliensis DSM 7358 alpha/beta hydrolase YP_008734960.1 3933417 D 1246995 CDS YP_008734961.1 556566536 17444301 3934752..3936023 1 NC_022657.1 COG1215 Glycosyltransferases, probably involved in cell wall biogenesis; putative xyloglucan glycosyltransferase 9 3936023 17444301 AFR_18150 Actinoplanes friuliensis DSM 7358 putative xyloglucan glycosyltransferase 9 YP_008734961.1 3934752 D 1246995 CDS YP_008734962.1 556566537 17444302 3936026..3937594 1 NC_022657.1 hypothetical protein 3937594 17444302 AFR_18155 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734962.1 3936026 D 1246995 CDS YP_008734963.1 556566538 17444303 3937591..3939714 1 NC_022657.1 hypothetical protein 3939714 17444303 AFR_18160 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734963.1 3937591 D 1246995 CDS YP_008734964.1 556566539 17444304 3939711..3940220 1 NC_022657.1 hypothetical protein 3940220 17444304 AFR_18165 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734964.1 3939711 D 1246995 CDS YP_008734965.1 556566540 17444305 complement(3940222..3941805) 1 NC_022657.1 COG1231 Monoamine oxidase; L-amino-acid oxidase 3941805 17444305 AFR_18170 Actinoplanes friuliensis DSM 7358 L-amino-acid oxidase YP_008734965.1 3940222 R 1246995 CDS YP_008734966.1 556566541 17444306 complement(3941902..3944547) 1 NC_022657.1 von Willebrand factor type D protein 3944547 17444306 AFR_18175 Actinoplanes friuliensis DSM 7358 von Willebrand factor type D protein YP_008734966.1 3941902 R 1246995 CDS YP_008734967.1 556566542 17444307 complement(3944582..3945013) 1 NC_022657.1 hypothetical protein 3945013 17444307 AFR_18180 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734967.1 3944582 R 1246995 CDS YP_008734968.1 556566543 17444308 3945192..3947030 1 NC_022657.1 COG2936 Predicted acyl esterases; x-prolyl-dipeptidyl aminopeptidase 3947030 17444308 AFR_18185 Actinoplanes friuliensis DSM 7358 x-prolyl-dipeptidyl aminopeptidase YP_008734968.1 3945192 D 1246995 CDS YP_008734969.1 556566544 17444309 3947165..3948373 1 NC_022657.1 COG1680 Beta-lactamase class C and other penicillin binding proteins; 6-aminohexanoate-dimer hydrolase 3948373 17444309 AFR_18190 Actinoplanes friuliensis DSM 7358 6-aminohexanoate-dimer hydrolase YP_008734969.1 3947165 D 1246995 CDS YP_008734970.1 556566545 17444310 complement(3948400..3949380) 1 NC_022657.1 hypothetical protein 3949380 17444310 AFR_18195 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734970.1 3948400 R 1246995 CDS YP_008734971.1 556566546 17444311 3949453..3950613 1 NC_022657.1 COG3211 Predicted phosphatase; hypothetical protein 3950613 17444311 AFR_18200 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734971.1 3949453 D 1246995 CDS YP_008734972.1 556566547 17444312 3950632..3950964 1 NC_022657.1 COG1734 DnaK suppressor protein; DnaK-like suppressor protein 3950964 17444312 AFR_18205 Actinoplanes friuliensis DSM 7358 DnaK-like suppressor protein YP_008734972.1 3950632 D 1246995 CDS YP_008734973.1 556566548 17444313 complement(3950958..3952553) 1 NC_022657.1 COG0840 Methyl-accepting chemotaxis protein; putative methyl-accepting chemotaxis protein 3952553 17444313 AFR_18210 Actinoplanes friuliensis DSM 7358 putative methyl-accepting chemotaxis protein YP_008734973.1 3950958 R 1246995 CDS YP_008734974.1 556566549 17444314 complement(3952659..3953747) 1 NC_022657.1 COG3839 ABC-type sugar transport systems, ATPase components; ABC transporter-like protein 3953747 17444314 AFR_18215 Actinoplanes friuliensis DSM 7358 ABC transporter-like protein YP_008734974.1 3952659 R 1246995 CDS YP_008734975.1 556566550 17444315 complement(3953761..3954543) 1 NC_022657.1 COG0395 ABC-type sugar transport system, permease component; binding-protein-dependent transport systems inner membrane component 3954543 17444315 AFR_18220 Actinoplanes friuliensis DSM 7358 binding-protein-dependent transport systems inner membrane component YP_008734975.1 3953761 R 1246995 CDS YP_008734976.1 556566551 17444316 complement(3954561..3955454) 1 NC_022657.1 COG1175 ABC-type sugar transport systems, permease components; carbohydrate ABC transporter membrane protein 1, CUT1 family 3955454 17444316 AFR_18225 Actinoplanes friuliensis DSM 7358 carbohydrate ABC transporter membrane protein 1, CUT1 family YP_008734976.1 3954561 R 1246995 CDS YP_008734977.1 556566552 17444317 complement(3955409..3956749) 1 NC_022657.1 COG1653 ABC-type sugar transport system, periplasmic component; carbohydrate ABC transporter substrate-binding protein 3956749 17444317 AFR_18230 Actinoplanes friuliensis DSM 7358 carbohydrate ABC transporter substrate-binding protein YP_008734977.1 3955409 R 1246995 CDS YP_008734978.1 556566553 17444318 complement(3956872..3957039) 1 NC_022657.1 hypothetical protein 3957039 17444318 AFR_18235 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734978.1 3956872 R 1246995 CDS YP_008734979.1 556566554 17444319 complement(3956994..3957665) 1 NC_022657.1 hypothetical protein 3957665 17444319 AFR_18240 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734979.1 3956994 R 1246995 CDS YP_008734980.1 556566555 17444320 complement(3957668..3959734) 1 NC_022657.1 COG0308 Aminopeptidase N; peptidase M1 membrane alanine aminopeptidase 3959734 17444320 AFR_18245 Actinoplanes friuliensis DSM 7358 peptidase M1 membrane alanine aminopeptidase YP_008734980.1 3957668 R 1246995 CDS YP_008734981.1 556566556 17444321 complement(3959828..3961078) 1 NC_022657.1 COG3268 Uncharacterized conserved protein; putative saccharopine dehydrogenase 3961078 17444321 AFR_18250 Actinoplanes friuliensis DSM 7358 putative saccharopine dehydrogenase YP_008734981.1 3959828 R 1246995 CDS YP_008734982.1 556566557 17444322 complement(3961130..3962677) 1 NC_022657.1 COG2199 FOG: GGDEF domain; Cellulose synthesis regulatory protein 3962677 17444322 AFR_18255 Actinoplanes friuliensis DSM 7358 Cellulose synthesis regulatory protein YP_008734982.1 3961130 R 1246995 CDS YP_008734983.1 556566558 17444323 complement(3962716..3963471) 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); short-chain dehydrogenase/reductase SDR 3963471 17444323 AFR_18260 Actinoplanes friuliensis DSM 7358 short-chain dehydrogenase/reductase SDR YP_008734983.1 3962716 R 1246995 CDS YP_008734984.1 556566559 17444324 complement(3963508..3964377) 1 NC_022657.1 hypothetical protein 3964377 17444324 AFR_18265 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734984.1 3963508 R 1246995 CDS YP_008734985.1 556566560 17444325 complement(3964374..3965522) 1 NC_022657.1 hypothetical protein 3965522 17444325 AFR_18270 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734985.1 3964374 R 1246995 CDS YP_008734986.1 556566561 17444326 3965554..3965787 1 NC_022657.1 hypothetical protein 3965787 17444326 AFR_18275 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734986.1 3965554 D 1246995 CDS YP_008734987.1 556566562 17444327 complement(3965776..3966798) 1 NC_022657.1 COG1609 Transcriptional regulators; LacI family transcriptional regulator 3966798 17444327 AFR_18280 Actinoplanes friuliensis DSM 7358 LacI family transcriptional regulator YP_008734987.1 3965776 R 1246995 CDS YP_008734988.1 556566563 17444328 3966901..3968055 1 NC_022657.1 COG0673 Predicted dehydrogenases and related proteins; oxidoreductase 3968055 17444328 AFR_18285 Actinoplanes friuliensis DSM 7358 oxidoreductase YP_008734988.1 3966901 D 1246995 CDS YP_008734989.1 556566564 17444329 3968052..3969206 1 NC_022657.1 hypothetical protein 3969206 17444329 AFR_18290 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734989.1 3968052 D 1246995 CDS YP_008734990.1 556566565 17444330 3969203..3970006 1 NC_022657.1 COG1082 Sugar phosphate isomerases/epimerases; xylose isomerase domain-containing protein 3970006 17444330 AFR_18295 Actinoplanes friuliensis DSM 7358 xylose isomerase domain-containing protein YP_008734990.1 3969203 D 1246995 CDS YP_008734991.1 556566566 17444331 complement(3970009..3970335) 1 NC_022657.1 hypothetical protein 3970335 17444331 AFR_18300 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734991.1 3970009 R 1246995 CDS YP_008734992.1 556566567 17444332 complement(3970417..3971451) 1 NC_022657.1 COG1609 Transcriptional regulators; putative LacI-family transcriptional regulator 3971451 17444332 AFR_18305 Actinoplanes friuliensis DSM 7358 putative LacI-family transcriptional regulator YP_008734992.1 3970417 R 1246995 CDS YP_008734993.1 556566568 17444333 3971590..3972813 1 NC_022657.1 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component; putative branched-chain amino acid ABC transporter substrate-binding protein 3972813 17444333 AFR_18310 Actinoplanes friuliensis DSM 7358 putative branched-chain amino acid ABC transporter substrate-binding protein YP_008734993.1 3971590 D 1246995 CDS YP_008734994.1 556566569 17444334 3972821..3973708 1 NC_022657.1 COG0559 Branched-chain amino acid ABC-type transport system, permease components; putative branched-chain amino acid ABC transporter permease 3973708 17444334 AFR_18315 Actinoplanes friuliensis DSM 7358 putative branched-chain amino acid ABC transporter permease YP_008734994.1 3972821 D 1246995 CDS YP_008734995.1 556566570 17444335 3973734..3974729 1 NC_022657.1 COG4177 ABC-type branched-chain amino acid transport system, permease component; putative branched-chain amino acid ABC transporter permease 3974729 17444335 AFR_18320 Actinoplanes friuliensis DSM 7358 putative branched-chain amino acid ABC transporter permease YP_008734995.1 3973734 D 1246995 CDS YP_008734996.1 556566571 17444336 3974726..3975454 1 NC_022657.1 COG0411 ABC-type branched-chain amino acid transport systems, ATPase component; putative ABC transporter ATP-binding protein 3975454 17444336 AFR_18325 Actinoplanes friuliensis DSM 7358 putative ABC transporter ATP-binding protein YP_008734996.1 3974726 D 1246995 CDS YP_008734997.1 556566572 17444337 3975444..3976193 1 NC_022657.1 COG0410 ABC-type branched-chain amino acid transport systems, ATPase component; putative ABC transporter ATP-binding protein 3976193 17444337 AFR_18330 Actinoplanes friuliensis DSM 7358 putative ABC transporter ATP-binding protein YP_008734997.1 3975444 D 1246995 CDS YP_008734998.1 556566573 17444338 3976206..3977123 1 NC_022657.1 hypothetical protein 3977123 17444338 AFR_18335 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734998.1 3976206 D 1246995 CDS YP_008734999.1 556566574 17444339 3977123..3979192 1 NC_022657.1 COG2133 Glucose/sorbosone dehydrogenases; hypothetical protein 3979192 17444339 AFR_18340 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008734999.1 3977123 D 1246995 CDS YP_008735000.1 556566575 17444340 3979268..3980206 1 NC_022657.1 COG0793 Periplasmic protease; Retinol-binding protein 3 3980206 17444340 AFR_18345 Actinoplanes friuliensis DSM 7358 Retinol-binding protein 3 YP_008735000.1 3979268 D 1246995 CDS YP_008735001.1 556566576 17444341 3980287..3980568 1 NC_022657.1 hypothetical protein 3980568 17444341 AFR_18350 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735001.1 3980287 D 1246995 CDS YP_008735002.1 556566577 17444342 3980565..3981653 1 NC_022657.1 hypothetical protein 3981653 17444342 AFR_18355 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735002.1 3980565 D 1246995 CDS YP_008735003.1 556566578 17444343 3981705..3981890 1 NC_022657.1 hypothetical protein 3981890 17444343 AFR_18360 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735003.1 3981705 D 1246995 CDS YP_008735004.1 556566579 17444344 3981967..3983160 1 NC_022657.1 COG0019 Diaminopimelate decarboxylase; Pyridoxal dependent decarboxylase 3983160 17444344 AFR_18365 Actinoplanes friuliensis DSM 7358 Pyridoxal dependent decarboxylase YP_008735004.1 3981967 D 1246995 CDS YP_008735005.1 556566580 17444345 3983121..3984623 1 NC_022657.1 hypothetical protein 3984623 17444345 AFR_18370 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735005.1 3983121 D 1246995 CDS YP_008735006.1 556566581 17444346 3984620..3986290 1 NC_022657.1 COG1132 ABC-type multidrug transport system, ATPase and permease components; ABC transporter permease 3986290 17444346 AFR_18375 Actinoplanes friuliensis DSM 7358 ABC transporter permease YP_008735006.1 3984620 D 1246995 CDS YP_008735007.1 556566582 17444347 3986287..3988029 1 NC_022657.1 COG1132 ABC-type multidrug transport system, ATPase and permease components; ABC transporter 3988029 17444347 AFR_18380 Actinoplanes friuliensis DSM 7358 ABC transporter YP_008735007.1 3986287 D 1246995 CDS YP_008735008.1 556566583 17444348 3988050..3989621 1 NC_022657.1 COG0010 Arginase/agmatinase/formimionoglutamate hydrolase, arginase family; Ureohydrolase 3989621 17444348 AFR_18385 Actinoplanes friuliensis DSM 7358 Ureohydrolase YP_008735008.1 3988050 D 1246995 CDS YP_008735009.1 556566584 17444349 3989618..3990544 1 NC_022657.1 hypothetical protein 3990544 17444349 AFR_18390 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735009.1 3989618 D 1246995 CDS YP_008735010.1 556566585 17444350 complement(3990678..3993302) 1 NC_022657.1 subtilin biosynthesis protein spaB 3993302 17444350 AFR_18395 Actinoplanes friuliensis DSM 7358 subtilin biosynthesis protein spaB YP_008735010.1 3990678 R 1246995 CDS YP_008735011.1 556566586 17444351 3993475..3994236 1 NC_022657.1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; SARP family transcriptional regulator 3994236 17444351 AFR_18400 Actinoplanes friuliensis DSM 7358 SARP family transcriptional regulator YP_008735011.1 3993475 D 1246995 CDS YP_008735012.1 556566587 17444352 complement(3994257..3994709) 1 NC_022657.1 hypothetical protein 3994709 17444352 AFR_18405 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735012.1 3994257 R 1246995 CDS YP_008735013.1 556566588 17444353 3994872..3996491 1 NC_022657.1 hypothetical protein 3996491 17444353 AFR_18410 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735013.1 3994872 D 1246995 CDS YP_008735014.1 556566589 17444354 complement(3996483..3998648) 1 NC_022657.1 COG3345 Alpha-galactosidase; alpha-galactosidase 3998648 17444354 AFR_18415 Actinoplanes friuliensis DSM 7358 alpha-galactosidase YP_008735014.1 3996483 R 1246995 CDS YP_008735015.1 556566590 17444355 complement(3998648..3999109) 1 NC_022657.1 COG1547 Uncharacterized conserved protein; hypothetical protein 3999109 17444355 AFR_18420 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735015.1 3998648 R 1246995 CDS YP_008735016.1 556566591 17444356 complement(3999093..4000244) 1 NC_022657.1 COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit; ring hydroxylating dioxygenase subunit 4000244 17444356 AFR_18425 Actinoplanes friuliensis DSM 7358 ring hydroxylating dioxygenase subunit YP_008735016.1 3999093 R 1246995 CDS YP_008735017.1 556566592 17444357 complement(4000241..4001392) 1 NC_022657.1 COG0665 Glycine/D-amino acid oxidases (deaminating); N-methyltryptophan oxidase 4001392 solA 17444357 solA Actinoplanes friuliensis DSM 7358 N-methyltryptophan oxidase YP_008735017.1 4000241 R 1246995 CDS YP_008735018.1 556566593 17444358 complement(4001401..4003761) 1 NC_022657.1 COG0665 Glycine/D-amino acid oxidases (deaminating); dimethylglycine oxidase 4003761 17444358 AFR_18435 Actinoplanes friuliensis DSM 7358 dimethylglycine oxidase YP_008735018.1 4001401 R 1246995 CDS YP_008735019.1 556566594 17444359 complement(4003749..4004687) 1 NC_022657.1 COG2113 ABC-type proline/glycine betaine transport systems, periplasmic components; proline/glycine betaine ABC transporter periplasmic component-like protein 4004687 17444359 AFR_18440 Actinoplanes friuliensis DSM 7358 proline/glycine betaine ABC transporter periplasmic component-like protein YP_008735019.1 4003749 R 1246995 CDS YP_008735020.1 556566595 17444360 complement(4004696..4006621) 1 NC_022657.1 COG4176 ABC-type proline/glycine betaine transport system, permease component; binding-protein-dependent transporter inner membrane component 4006621 17444360 AFR_18445 Actinoplanes friuliensis DSM 7358 binding-protein-dependent transporter inner membrane component YP_008735020.1 4004696 R 1246995 CDS YP_008735021.1 556566596 17444361 complement(4006618..4007652) 1 NC_022657.1 COG4175 ABC-type proline/glycine betaine transport system, ATPase component; glycine betaine/L-proline ABC transporter ATPase 4007652 17444361 AFR_18450 Actinoplanes friuliensis DSM 7358 glycine betaine/L-proline ABC transporter ATPase YP_008735021.1 4006618 R 1246995 CDS YP_008735022.1 556566597 17444362 complement(4007663..4009219) 1 NC_022657.1 COG2303 Choline dehydrogenase and related flavoproteins; glucose-methanol-choline oxidoreductase 4009219 17444362 AFR_18455 Actinoplanes friuliensis DSM 7358 glucose-methanol-choline oxidoreductase YP_008735022.1 4007663 R 1246995 CDS YP_008735023.1 556566598 17444363 4009422..4010246 1 NC_022657.1 COG0586 Uncharacterized membrane-associated protein; hypothetical protein 4010246 17444363 AFR_18460 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735023.1 4009422 D 1246995 CDS YP_008735024.1 556566599 17444364 4010796..4011593 1 NC_022657.1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; regulatory protein LuxR 4011593 17444364 AFR_18465 Actinoplanes friuliensis DSM 7358 regulatory protein LuxR YP_008735024.1 4010796 D 1246995 CDS YP_008735025.1 556566600 17444365 4011772..4012725 1 NC_022657.1 COG1131 ABC-type multidrug transport system, ATPase component; daunorubicin ABC transporter ATPase 4012725 17444365 AFR_18470 Actinoplanes friuliensis DSM 7358 daunorubicin ABC transporter ATPase YP_008735025.1 4011772 D 1246995 CDS YP_008735026.1 556566601 17444366 4012722..4013795 1 NC_022657.1 COG0031 Cysteine synthase; cystathionine beta-synthase/cysteine synthase 4013795 17444366 AFR_18475 Actinoplanes friuliensis DSM 7358 cystathionine beta-synthase/cysteine synthase YP_008735026.1 4012722 D 1246995 CDS YP_008735027.1 556566602 17444367 4013792..4015234 1 NC_022657.1 COG0165 Argininosuccinate lyase; argininosuccinate lyase 4015234 17444367 AFR_18480 Actinoplanes friuliensis DSM 7358 argininosuccinate lyase YP_008735027.1 4013792 D 1246995 CDS YP_008735028.1 556566603 17444368 4015231..4016454 1 NC_022657.1 COG0439 Biotin carboxylase; argininosuccinate lyase 4016454 17444368 AFR_18485 Actinoplanes friuliensis DSM 7358 argininosuccinate lyase YP_008735028.1 4015231 D 1246995 CDS YP_008735029.1 556566604 17444369 4016451..4019639 1 NC_022657.1 COG1020 Non-ribosomal peptide synthetase modules and related proteins; non-ribosomal peptide synthetase 4019639 17444369 AFR_18490 Actinoplanes friuliensis DSM 7358 non-ribosomal peptide synthetase YP_008735029.1 4016451 D 1246995 CDS YP_008735030.1 556566605 17444370 4019636..4020544 1 NC_022657.1 COG4542 Protein involved in propanediol utilization, and related proteins (includes coumermycin biosynthetic protein), possible kinase; GHMP kinase 4020544 17444370 AFR_18495 Actinoplanes friuliensis DSM 7358 GHMP kinase YP_008735030.1 4019636 D 1246995 CDS YP_008735031.1 556566606 17444371 complement(4020600..4021505) 1 NC_022657.1 SyrP-like protein 4021505 17444371 AFR_18500 Actinoplanes friuliensis DSM 7358 SyrP-like protein YP_008735031.1 4020600 R 1246995 CDS YP_008735032.1 556566607 17444372 complement(4021522..4022361) 1 NC_022657.1 COG0842 ABC-type multidrug transport system, permease component; ABC-type multidrug transport system, permease component 4022361 17444372 AFR_18505 Actinoplanes friuliensis DSM 7358 ABC-type multidrug transport system, permease component YP_008735032.1 4021522 R 1246995 CDS YP_008735033.1 556566608 17444373 complement(4022358..4023605) 1 NC_022657.1 COG4865 Glutamate mutase epsilon subunit; methylaspartate mutase E chain family protein 4023605 17444373 AFR_18510 Actinoplanes friuliensis DSM 7358 methylaspartate mutase E chain family protein YP_008735033.1 4022358 R 1246995 CDS YP_008735034.1 556566609 17444374 complement(4023602..4024039) 1 NC_022657.1 COG2185 Methylmalonyl-CoA mutase, C-terminal domain/subunit (cobalamin-binding); B12 binding domain protein 4024039 17444374 AFR_18515 Actinoplanes friuliensis DSM 7358 B12 binding domain protein YP_008735034.1 4023602 R 1246995 CDS YP_008735035.1 556566610 17444375 4024309..4026075 1 NC_022657.1 COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II; acyl-CoA synthase 4026075 17444375 AFR_18520 Actinoplanes friuliensis DSM 7358 acyl-CoA synthase YP_008735035.1 4024309 D 1246995 CDS YP_008735036.1 556566611 17444376 4026072..4027610 1 NC_022657.1 COG1960 Acyl-CoA dehydrogenases; non-ribosomal peptide synthetase/acyl-CoA dehydrogenase fusion protein 4027610 17444376 AFR_18525 Actinoplanes friuliensis DSM 7358 non-ribosomal peptide synthetase/acyl-CoA dehydrogenase fusion protein YP_008735036.1 4026072 D 1246995 CDS YP_008735037.1 556566612 17444377 4027607..4028314 1 NC_022657.1 oxidoreductase 4028314 17444377 AFR_18530 Actinoplanes friuliensis DSM 7358 oxidoreductase YP_008735037.1 4027607 D 1246995 CDS YP_008735038.1 556566613 17444378 4028332..4028598 1 NC_022657.1 COG3321 Polyketide synthase modules and related proteins; hypothetical protein 4028598 17444378 AFR_18535 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735038.1 4028332 D 1246995 CDS YP_008735039.1 556566614 17444379 4028634..4038065 1 NC_022657.1 COG1020 Non-ribosomal peptide synthetase modules and related proteins; amino acid adenylation domain-containing protein 4038065 17444379 AFR_18540 Actinoplanes friuliensis DSM 7358 amino acid adenylation domain-containing protein YP_008735039.1 4028634 D 1246995 CDS YP_008735040.1 556566615 17444380 4038062..4058047 1 NC_022657.1 COG1020 Non-ribosomal peptide synthetase modules and related proteins; non-ribosomal peptide synthetase 4058047 17444380 AFR_18545 Actinoplanes friuliensis DSM 7358 non-ribosomal peptide synthetase YP_008735040.1 4038062 D 1246995 CDS YP_008735041.1 556566616 17444381 4058032..4065159 1 NC_022657.1 COG1020 Non-ribosomal peptide synthetase modules and related proteins; non-ribosomal peptide synthetase 4065159 17444381 AFR_18550 Actinoplanes friuliensis DSM 7358 non-ribosomal peptide synthetase YP_008735041.1 4058032 D 1246995 CDS YP_008735042.1 556566617 17444382 4065189..4065401 1 NC_022657.1 COG3251 Uncharacterized protein conserved in bacteria; MbtH-like protein 4065401 17444382 AFR_18555 Actinoplanes friuliensis DSM 7358 MbtH-like protein YP_008735042.1 4065189 D 1246995 CDS YP_008735043.1 556566618 17444383 4065477..4066283 1 NC_022657.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); hydrolase 4066283 17444383 AFR_18560 Actinoplanes friuliensis DSM 7358 hydrolase YP_008735043.1 4065477 D 1246995 CDS YP_008735044.1 556566619 17444384 complement(4066368..4068638) 1 NC_022657.1 COG2409 Predicted drug exporters of the RND superfamily; RND superfamily drug exporter-like protein 4068638 17444384 AFR_18565 Actinoplanes friuliensis DSM 7358 RND superfamily drug exporter-like protein YP_008735044.1 4066368 R 1246995 CDS YP_008735045.1 556566620 17444385 4068967..4069986 1 NC_022657.1 COG2423 Predicted ornithine cyclodeaminase, mu-crystallin homolog; ornithine cyclodeaminase 4069986 17444385 AFR_18570 Actinoplanes friuliensis DSM 7358 ornithine cyclodeaminase YP_008735045.1 4068967 D 1246995 CDS YP_008735046.1 556566621 17444386 complement(4069990..4070634) 1 NC_022657.1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; response regulator receiver protein 4070634 17444386 AFR_18575 Actinoplanes friuliensis DSM 7358 response regulator receiver protein YP_008735046.1 4069990 R 1246995 CDS YP_008735047.1 556566622 17444387 complement(4070625..4071818) 1 NC_022657.1 COG4585 Signal transduction histidine kinase; putative two-component system sensor kinase 4071818 17444387 AFR_18580 Actinoplanes friuliensis DSM 7358 putative two-component system sensor kinase YP_008735047.1 4070625 R 1246995 CDS YP_008735048.1 556566623 17444388 4071994..4072614 1 NC_022657.1 acid phosphatase 4072614 17444388 AFR_18585 Actinoplanes friuliensis DSM 7358 acid phosphatase YP_008735048.1 4071994 D 1246995 CDS YP_008735049.1 556566624 17444389 4072758..4074347 1 NC_022657.1 COG0477 Permeases of the major facilitator superfamily; putative MFS transporter 4074347 17444389 AFR_18590 Actinoplanes friuliensis DSM 7358 putative MFS transporter YP_008735049.1 4072758 D 1246995 CDS YP_008735050.1 556566625 17444390 4074397..4075011 1 NC_022657.1 COG1309 Transcriptional regulator; putative TetR-family transcriptional regulator 4075011 17444390 AFR_18595 Actinoplanes friuliensis DSM 7358 putative TetR-family transcriptional regulator YP_008735050.1 4074397 D 1246995 CDS YP_008735051.1 556566626 17444391 4075008..4075976 1 NC_022657.1 COG1171 Threonine dehydratase; threonine dehydratase 4075976 17444391 AFR_18600 Actinoplanes friuliensis DSM 7358 threonine dehydratase YP_008735051.1 4075008 D 1246995 CDS YP_008735052.1 556566627 17444392 4076037..4076909 1 NC_022657.1 hypothetical protein 4076909 17444392 AFR_18605 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735052.1 4076037 D 1246995 CDS YP_008735053.1 556566628 17444393 4077123..4078316 1 NC_022657.1 COG0477 Permeases of the major facilitator superfamily; hypothetical protein 4078316 17444393 AFR_18610 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735053.1 4077123 D 1246995 CDS YP_008735054.1 556566629 17444394 4078394..4078849 1 NC_022657.1 hypothetical protein 4078849 17444394 AFR_18615 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735054.1 4078394 D 1246995 CDS YP_008735055.1 556566630 17444395 complement(4078800..4080326) 1 NC_022657.1 COG2199 FOG: GGDEF domain; diguanylate cyclase 4080326 17444395 AFR_18620 Actinoplanes friuliensis DSM 7358 diguanylate cyclase YP_008735055.1 4078800 R 1246995 CDS YP_008735056.1 556566631 17444396 complement(4080371..4080811) 1 NC_022657.1 hypothetical protein 4080811 17444396 AFR_18625 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735056.1 4080371 R 1246995 CDS YP_008735057.1 556566632 17444397 complement(4080946..4081383) 1 NC_022657.1 COG0071 Molecular chaperone (small heat shock protein); 17.5 kDa class I heat shock protein 4081383 17444397 AFR_18630 Actinoplanes friuliensis DSM 7358 17.5 kDa class I heat shock protein YP_008735057.1 4080946 R 1246995 CDS YP_008735058.1 556566633 17444398 4081593..4082114 1 NC_022657.1 hypothetical protein 4082114 17444398 AFR_18635 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735058.1 4081593 D 1246995 CDS YP_008735059.1 556566634 17444399 4082104..4083213 1 NC_022657.1 COG0498 Threonine synthase; pyridoxal-5'-phosphate-dependent protein subunit beta 4083213 17444399 AFR_18640 Actinoplanes friuliensis DSM 7358 pyridoxal-5'-phosphate-dependent protein subunit beta YP_008735059.1 4082104 D 1246995 CDS YP_008735060.1 556566635 17444400 4083482..4084429 1 NC_022657.1 hypothetical protein 4084429 17444400 AFR_18645 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735060.1 4083482 D 1246995 CDS YP_008735061.1 556566636 17444401 complement(4084433..4085311) 1 NC_022657.1 COG3384 Uncharacterized conserved protein; Extradiol ring-cleavage dioxygenase class III protein subunit B 4085311 17444401 AFR_18650 Actinoplanes friuliensis DSM 7358 Extradiol ring-cleavage dioxygenase class III protein subunit B YP_008735061.1 4084433 R 1246995 CDS YP_008735062.1 556566637 17444402 4085373..4085747 1 NC_022657.1 DoxX family protein 4085747 17444402 AFR_18655 Actinoplanes friuliensis DSM 7358 DoxX family protein YP_008735062.1 4085373 D 1246995 CDS YP_008735063.1 556566638 17444403 complement(4085761..4087947) 1 NC_022657.1 Ig family protein 4087947 17444403 AFR_18660 Actinoplanes friuliensis DSM 7358 Ig family protein YP_008735063.1 4085761 R 1246995 CDS YP_008735064.1 556566639 17444404 4088187..4089332 1 NC_022657.1 COG1587 Uroporphyrinogen-III synthase; bifunctional uroporphyrinogen-III synthetase/response regulator domain protein 4089332 17444404 AFR_18665 Actinoplanes friuliensis DSM 7358 bifunctional uroporphyrinogen-III synthetase/response regulator domain protein YP_008735064.1 4088187 D 1246995 CDS YP_008735065.1 556566640 17444405 4089329..4089991 1 NC_022657.1 COG2138 Uncharacterized conserved protein; sirohydrochlorin ferrochelatase 4089991 17444405 AFR_18670 Actinoplanes friuliensis DSM 7358 sirohydrochlorin ferrochelatase YP_008735065.1 4089329 D 1246995 CDS YP_008735066.1 556566641 17444406 4092504..4094981 1 NC_022657.1 COG1251 NAD(P)H-nitrite reductase; nitrite reductase (NAD(P)H) large subunit 4094981 17444406 AFR_18685 Actinoplanes friuliensis DSM 7358 nitrite reductase (NAD(P)H) large subunit YP_008735066.1 4092504 D 1246995 CDS YP_008735067.1 556566642 17444407 4094978..4095301 1 NC_022657.1 COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases; putative nitrite reductase small subunit 4095301 17444407 AFR_18690 Actinoplanes friuliensis DSM 7358 putative nitrite reductase small subunit YP_008735067.1 4094978 D 1246995 CDS YP_008735068.1 556566643 17444408 4095298..4096635 1 NC_022657.1 COG2223 Nitrate/nitrite transporter; putative nitrate extrusion protein 4096635 17444408 AFR_18695 Actinoplanes friuliensis DSM 7358 putative nitrate extrusion protein YP_008735068.1 4095298 D 1246995 CDS YP_008735069.1 556566644 17444409 complement(4096649..4097281) 1 NC_022657.1 hypothetical protein 4097281 17444409 AFR_18700 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735069.1 4096649 R 1246995 CDS YP_008735070.1 556566645 17444410 complement(4097298..4097540) 1 NC_022657.1 hypothetical protein 4097540 17444410 AFR_18705 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735070.1 4097298 R 1246995 CDS YP_008735071.1 556566646 17444411 complement(4098073..4099290) 1 NC_022657.1 COG2942 N-acyl-D-glucosamine 2-epimerase; N-acylglucosamine 2-epimerase 4099290 17444411 AFR_18710 Actinoplanes friuliensis DSM 7358 N-acylglucosamine 2-epimerase YP_008735071.1 4098073 R 1246995 CDS YP_008735072.1 556566647 17444412 complement(4099332..4100345) 1 NC_022657.1 COG5640 Secreted trypsin-like serine protease; Thrombin-like enzyme gussurobin 4100345 17444412 AFR_18715 Actinoplanes friuliensis DSM 7358 Thrombin-like enzyme gussurobin YP_008735072.1 4099332 R 1246995 CDS YP_008735073.1 556566648 17444413 complement(4100437..4101288) 1 NC_022657.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); alpha/beta hydrolase fold protein 4101288 17444413 AFR_18720 Actinoplanes friuliensis DSM 7358 alpha/beta hydrolase fold protein YP_008735073.1 4100437 R 1246995 CDS YP_008735074.1 556566649 17444414 complement(4101285..4102127) 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); 3-oxoacyl-ACP reductase 4102127 17444414 AFR_18725 Actinoplanes friuliensis DSM 7358 3-oxoacyl-ACP reductase YP_008735074.1 4101285 R 1246995 CDS YP_008735075.1 556566650 17444415 complement(4102124..4103551) 1 NC_022657.1 COG2072 Predicted flavoprotein involved in K+ transport; putative FAD-dependent monooxygenase 4103551 17444415 AFR_18730 Actinoplanes friuliensis DSM 7358 putative FAD-dependent monooxygenase YP_008735075.1 4102124 R 1246995 CDS YP_008735076.1 556566651 17444416 4103651..4104658 1 NC_022657.1 COG2207 AraC-type DNA-binding domain-containing proteins; transcriptional regulator 4104658 17444416 AFR_18735 Actinoplanes friuliensis DSM 7358 transcriptional regulator YP_008735076.1 4103651 D 1246995 CDS YP_008735077.1 556566652 17444417 complement(4104612..4104908) 1 NC_022657.1 hypothetical protein 4104908 17444417 AFR_18740 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735077.1 4104612 R 1246995 CDS YP_008735078.1 556566653 17444418 complement(4104905..4105576) 1 NC_022657.1 COG1309 Transcriptional regulator; putative TetR-family transcriptional regulator 4105576 17444418 AFR_18745 Actinoplanes friuliensis DSM 7358 putative TetR-family transcriptional regulator YP_008735078.1 4104905 R 1246995 CDS YP_008735079.1 556566654 17444419 4105630..4106514 1 NC_022657.1 hypothetical protein 4106514 17444419 AFR_18750 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735079.1 4105630 D 1246995 CDS YP_008735080.1 556566655 17444420 4106571..4107695 1 NC_022657.1 COG4335 DNA alkylation repair enzyme; DNA alkylation repair protein 4107695 17444420 AFR_18755 Actinoplanes friuliensis DSM 7358 DNA alkylation repair protein YP_008735080.1 4106571 D 1246995 CDS YP_008735081.1 556566656 17444421 complement(4107671..4108321) 1 NC_022657.1 COG2761 Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis; DSBA oxidoreductase 4108321 17444421 AFR_18760 Actinoplanes friuliensis DSM 7358 DSBA oxidoreductase YP_008735081.1 4107671 R 1246995 CDS YP_008735082.1 556566657 17444422 complement(4108506..4109462) 1 NC_022657.1 hypothetical protein 4109462 17444422 AFR_18765 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735082.1 4108506 R 1246995 CDS YP_008735083.1 556566658 17444423 4109665..4110219 1 NC_022657.1 hypothetical protein 4110219 17444423 AFR_18770 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735083.1 4109665 D 1246995 CDS YP_008735084.1 556566659 17444424 4110257..4111567 1 NC_022657.1 hypothetical protein 4111567 17444424 AFR_18775 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735084.1 4110257 D 1246995 CDS YP_008735085.1 556566660 17444428 4112172..4112957 1 NC_022657.1 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases; 6-phosphogluconate dehydrogenase 4112957 17444428 AFR_18780 Actinoplanes friuliensis DSM 7358 6-phosphogluconate dehydrogenase YP_008735085.1 4112172 D 1246995 CDS YP_008735086.1 556566661 17444429 4113041..4114249 1 NC_022657.1 hypothetical protein 4114249 17444429 AFR_18785 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735086.1 4113041 D 1246995 CDS YP_008735087.1 556566662 17444430 complement(4114233..4114565) 1 NC_022657.1 COG0662 Mannose-6-phosphate isomerase; hypothetical protein 4114565 17444430 AFR_18790 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735087.1 4114233 R 1246995 CDS YP_008735088.1 556566663 17444431 4114636..4115547 1 NC_022657.1 COG0803 ABC-type metal ion transport system, periplasmic component/surface adhesin; putative ABC transporter substrate-binding protein 4115547 17444431 AFR_18795 Actinoplanes friuliensis DSM 7358 putative ABC transporter substrate-binding protein YP_008735088.1 4114636 D 1246995 CDS YP_008735089.1 556566664 17444432 4115540..4116277 1 NC_022657.1 COG1121 ABC-type Mn/Zn transport systems, ATPase component; manganese/zinc/iron transport system ATP- binding protein 4116277 17444432 AFR_18800 Actinoplanes friuliensis DSM 7358 manganese/zinc/iron transport system ATP- binding protein YP_008735089.1 4115540 D 1246995 CDS YP_008735090.1 556566665 17444433 4116277..4117107 1 NC_022657.1 COG1108 ABC-type Mn2+/Zn2+ transport systems, permease components; Chelated iron transport system membrane protein yfeD 4117107 17444433 AFR_18805 Actinoplanes friuliensis DSM 7358 Chelated iron transport system membrane protein yfeD YP_008735090.1 4116277 D 1246995 CDS YP_008735091.1 556566666 17444434 4117104..4117898 1 NC_022657.1 COG1108 ABC-type Mn2+/Zn2+ transport systems, permease components; Chelated iron transport system membrane protein yfeD 4117898 17444434 AFR_18810 Actinoplanes friuliensis DSM 7358 Chelated iron transport system membrane protein yfeD YP_008735091.1 4117104 D 1246995 CDS YP_008735092.1 556566667 17444435 4117895..4118179 1 NC_022657.1 COG0640 Predicted transcriptional regulators; putative ArsR-family transcriptional regulator 4118179 17444435 AFR_18815 Actinoplanes friuliensis DSM 7358 putative ArsR-family transcriptional regulator YP_008735092.1 4117895 D 1246995 CDS YP_008735093.1 556566668 17444436 complement(4118361..4118738) 1 NC_022657.1 hypothetical protein 4118738 17444436 AFR_18820 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735093.1 4118361 R 1246995 CDS YP_008735094.1 556566669 17444437 4118704..4119459 1 NC_022657.1 COG4124 Beta-mannanase; beta-mannanase-like protein 4119459 17444437 AFR_18825 Actinoplanes friuliensis DSM 7358 beta-mannanase-like protein YP_008735094.1 4118704 D 1246995 CDS YP_008735095.1 556566670 17444438 complement(4119456..4120370) 1 NC_022657.1 Ricin 4120370 17444438 AFR_18830 Actinoplanes friuliensis DSM 7358 Ricin YP_008735095.1 4119456 R 1246995 CDS YP_008735096.1 556566671 17444439 complement(4120501..4121007) 1 NC_022657.1 hypothetical protein 4121007 17444439 AFR_18835 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735096.1 4120501 R 1246995 CDS YP_008735097.1 556566672 17444440 4122769..4123899 1 NC_022657.1 COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases; peptidase dimerization domain-containing protein 4123899 17444440 AFR_18850 Actinoplanes friuliensis DSM 7358 peptidase dimerization domain-containing protein YP_008735097.1 4122769 D 1246995 CDS YP_008735098.1 556566673 17444441 4123896..4124753 1 NC_022657.1 COG3375 Uncharacterized conserved protein; hypothetical protein 4124753 17444441 AFR_18855 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735098.1 4123896 D 1246995 CDS YP_008735099.1 556566674 17444442 4124750..4125865 1 NC_022657.1 COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily; mandelate racemase/muconate lactonizing protein 4125865 17444442 AFR_18860 Actinoplanes friuliensis DSM 7358 mandelate racemase/muconate lactonizing protein YP_008735099.1 4124750 D 1246995 CDS YP_008735100.1 556566675 17444443 4126140..4126685 1 NC_022657.1 COG1652 Uncharacterized protein containing LysM domain; secreted protein 4126685 17444443 AFR_18865 Actinoplanes friuliensis DSM 7358 secreted protein YP_008735100.1 4126140 D 1246995 CDS YP_008735101.1 556566676 17444444 4126764..4128059 1 NC_022657.1 hypothetical protein 4128059 17444444 AFR_18870 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735101.1 4126764 D 1246995 CDS YP_008735102.1 556566677 17444445 4128056..4130695 1 NC_022657.1 hypothetical protein 4130695 17444445 AFR_18875 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735102.1 4128056 D 1246995 CDS YP_008735103.1 556566678 17444446 4130718..4132718 1 NC_022657.1 COG1874 Beta-galactosidase; putative beta-galactosidase 4132718 17444446 AFR_18880 Actinoplanes friuliensis DSM 7358 putative beta-galactosidase YP_008735103.1 4130718 D 1246995 CDS YP_008735104.1 556566679 17444447 complement(4132712..4134058) 1 NC_022657.1 COG1409 Predicted phosphohydrolases; alkaline phosphatase 4134058 17444447 AFR_18885 Actinoplanes friuliensis DSM 7358 alkaline phosphatase YP_008735104.1 4132712 R 1246995 CDS YP_008735105.1 556566680 17444448 4134159..4135379 1 NC_022657.1 COG0477 Permeases of the major facilitator superfamily; major facilitator transporter 4135379 17444448 AFR_18890 Actinoplanes friuliensis DSM 7358 major facilitator transporter YP_008735105.1 4134159 D 1246995 CDS YP_008735106.1 556566681 17444449 4135376..4136344 1 NC_022657.1 COG0823 Periplasmic component of the Tol biopolymer transport system; hypothetical protein 4136344 17444449 AFR_18895 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735106.1 4135376 D 1246995 CDS YP_008735107.1 556566682 17444450 4136568..4137095 1 NC_022657.1 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; putative RNA polymerase ECF-subfamily sigma factor 4137095 17444450 AFR_18900 Actinoplanes friuliensis DSM 7358 putative RNA polymerase ECF-subfamily sigma factor YP_008735107.1 4136568 D 1246995 CDS YP_008735108.1 556566683 17444451 4137079..4137840 1 NC_022657.1 hypothetical protein 4137840 17444451 AFR_18905 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735108.1 4137079 D 1246995 CDS YP_008735109.1 556566684 17444452 complement(4137827..4139404) 1 NC_022657.1 COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; Cellulose synthesis regulatory protein 4139404 17444452 AFR_18910 Actinoplanes friuliensis DSM 7358 Cellulose synthesis regulatory protein YP_008735109.1 4137827 R 1246995 CDS YP_008735110.1 556566685 17444453 complement(4139522..4140886) 1 NC_022657.1 COG2730 Endoglucanase; putative glycosyl hydrolase 4140886 17444453 AFR_18915 Actinoplanes friuliensis DSM 7358 putative glycosyl hydrolase YP_008735110.1 4139522 R 1246995 CDS YP_008735111.1 556566686 17444454 4141148..4143796 1 NC_022657.1 COG5297 Cellobiohydrolase A (1,4-beta-cellobiosidase A); endoglucanase, putative 4143796 17444454 AFR_18920 Actinoplanes friuliensis DSM 7358 endoglucanase, putative YP_008735111.1 4141148 D 1246995 CDS YP_008735112.1 556566687 17444455 4143825..4146749 1 NC_022657.1 putative glycosyl hydrolase 4146749 17444455 AFR_18925 Actinoplanes friuliensis DSM 7358 putative glycosyl hydrolase YP_008735112.1 4143825 D 1246995 CDS YP_008735113.1 556566688 17444456 4146761..4147882 1 NC_022657.1 COG3397 Uncharacterized protein conserved in bacteria; GlcNAc-binding protein A 4147882 17444456 AFR_18930 Actinoplanes friuliensis DSM 7358 GlcNAc-binding protein A YP_008735113.1 4146761 D 1246995 CDS YP_008735114.1 556566689 17444457 complement(4147929..4148921) 1 NC_022657.1 COG1609 Transcriptional regulators; HTH-type transcriptional repressor PurR 4148921 17444457 AFR_18935 Actinoplanes friuliensis DSM 7358 HTH-type transcriptional repressor PurR YP_008735114.1 4147929 R 1246995 CDS YP_008735115.1 556566690 17444458 4149287..4150273 1 NC_022657.1 COG1879 ABC-type sugar transport system, periplasmic component; HTH-type transcriptional repressor purR 4150273 17444458 AFR_18940 Actinoplanes friuliensis DSM 7358 HTH-type transcriptional repressor purR YP_008735115.1 4149287 D 1246995 CDS YP_008735116.1 556566691 17444459 4150343..4151866 1 NC_022657.1 COG1129 ABC-type sugar transport system, ATPase component; simple sugar transport system ATP-binding protein 4151866 17444459 AFR_18945 Actinoplanes friuliensis DSM 7358 simple sugar transport system ATP-binding protein YP_008735116.1 4150343 D 1246995 CDS YP_008735117.1 556566692 17444460 4151863..4152894 1 NC_022657.1 COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components; ABC transporter permease 4152894 17444460 AFR_18950 Actinoplanes friuliensis DSM 7358 ABC transporter permease YP_008735117.1 4151863 D 1246995 CDS YP_008735118.1 556566693 17444461 4152891..4153904 1 NC_022657.1 COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components; inner membrane ABC transporter permease protein YjfF 4153904 17444461 AFR_18955 Actinoplanes friuliensis DSM 7358 inner membrane ABC transporter permease protein YjfF YP_008735118.1 4152891 D 1246995 CDS YP_008735119.1 556566694 17444462 4154055..4154609 1 NC_022657.1 hypothetical protein 4154609 17444462 AFR_18960 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735119.1 4154055 D 1246995 CDS YP_008735120.1 556566695 17444463 4154674..4155171 1 NC_022657.1 COG0590 Cytosine/adenosine deaminases; zinc-binding CMP/dCMP deaminase 4155171 17444463 AFR_18965 Actinoplanes friuliensis DSM 7358 zinc-binding CMP/dCMP deaminase YP_008735120.1 4154674 D 1246995 CDS YP_008735121.1 556566696 17444464 4155168..4156046 1 NC_022657.1 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases; F420-dependent dehydrogenase 4156046 17444464 AFR_18970 Actinoplanes friuliensis DSM 7358 F420-dependent dehydrogenase YP_008735121.1 4155168 D 1246995 CDS YP_008735122.1 556566697 17444465 4156043..4157344 1 NC_022657.1 COG0477 Permeases of the major facilitator superfamily; major facilitator superfamily protein 4157344 17444465 AFR_18975 Actinoplanes friuliensis DSM 7358 major facilitator superfamily protein YP_008735122.1 4156043 D 1246995 CDS YP_008735123.1 556566698 17444466 complement(4157231..4158700) 1 NC_022657.1 COG0477 Permeases of the major facilitator superfamily; Putative multidrug resistance protein mdtD 4158700 17444466 AFR_18980 Actinoplanes friuliensis DSM 7358 Putative multidrug resistance protein mdtD YP_008735123.1 4157231 R 1246995 CDS YP_008735124.1 556566699 17444467 4158798..4159352 1 NC_022657.1 COG1309 Transcriptional regulator; putative transcriptional regulator, TetR family protein 4159352 17444467 AFR_18985 Actinoplanes friuliensis DSM 7358 putative transcriptional regulator, TetR family protein YP_008735124.1 4158798 D 1246995 CDS YP_008735125.1 556566700 17444468 complement(4159353..4159895) 1 NC_022657.1 hypothetical protein 4159895 17444468 AFR_18990 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735125.1 4159353 R 1246995 CDS YP_008735126.1 556566701 17444469 complement(4159996..4160253) 1 NC_022657.1 COG0254 Ribosomal protein L31; 50S ribosomal protein L31 type B 4160253 rpmE2 17444469 rpmE2 Actinoplanes friuliensis DSM 7358 50S ribosomal protein L31 type B YP_008735126.1 4159996 R 1246995 CDS YP_008735127.1 556566702 17444470 complement(4160257..4161456) 1 NC_022657.1 COG0523 Putative GTPases (G3E family); putative cobalamin synthesis CobW-like protein 4161456 17444470 AFR_19000 Actinoplanes friuliensis DSM 7358 putative cobalamin synthesis CobW-like protein YP_008735127.1 4160257 R 1246995 CDS YP_008735128.1 556566703 17444471 complement(4161482..4162642) 1 NC_022657.1 COG3864 Uncharacterized protein conserved in bacteria; hypothetical protein 4162642 17444471 AFR_19005 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735128.1 4161482 R 1246995 CDS YP_008735129.1 556566704 17444472 complement(4162639..4163808) 1 NC_022657.1 COG0714 MoxR-like ATPases; ATPase AAA 4163808 17444472 AFR_19010 Actinoplanes friuliensis DSM 7358 ATPase AAA YP_008735129.1 4162639 R 1246995 CDS YP_008735130.1 556566705 17444473 complement(4163805..4164947) 1 NC_022657.1 hypothetical protein 4164947 17444473 AFR_19015 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735130.1 4163805 R 1246995 CDS YP_008735131.1 556566706 17444474 complement(4164944..4166272) 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); hypothetical protein 4166272 17444474 AFR_19020 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735131.1 4164944 R 1246995 CDS YP_008735132.1 556566707 17444476 complement(4167623..4169839) 1 NC_022657.1 COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs; dehydrogenase 4169839 17444476 AFR_19035 Actinoplanes friuliensis DSM 7358 dehydrogenase YP_008735132.1 4167623 R 1246995 CDS YP_008735133.1 556566708 17444477 complement(4169836..4170807) 1 NC_022657.1 COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs; xanthine dehydrogenase 4170807 17444477 AFR_19040 Actinoplanes friuliensis DSM 7358 xanthine dehydrogenase YP_008735133.1 4169836 R 1246995 CDS YP_008735134.1 556566709 17444478 complement(4170804..4171310) 1 NC_022657.1 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs; oxidoreductase with iron-sulfur subunit 4171310 17444478 AFR_19045 Actinoplanes friuliensis DSM 7358 oxidoreductase with iron-sulfur subunit YP_008735134.1 4170804 R 1246995 CDS YP_008735135.1 556566710 17444479 complement(4171330..4171896) 1 NC_022657.1 COG1853 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family; NADH-FMN oxidoreductase 4171896 17444479 AFR_19050 Actinoplanes friuliensis DSM 7358 NADH-FMN oxidoreductase YP_008735135.1 4171330 R 1246995 CDS YP_008735136.1 556566711 17444480 complement(4171898..4172302) 1 NC_022657.1 hypothetical protein 4172302 17444480 AFR_19055 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735136.1 4171898 R 1246995 CDS YP_008735137.1 556566712 17444481 4172395..4172967 1 NC_022657.1 COG1309 Transcriptional regulator; TetR family transcriptional regulator 4172967 17444481 AFR_19060 Actinoplanes friuliensis DSM 7358 TetR family transcriptional regulator YP_008735137.1 4172395 D 1246995 CDS YP_008735138.1 556566713 17444484 complement(4173475..4175007) 1 NC_022657.1 COG0666 FOG: Ankyrin repeat; Ankyrin-2 4175007 17444484 AFR_19065 Actinoplanes friuliensis DSM 7358 Ankyrin-2 YP_008735138.1 4173475 R 1246995 CDS YP_008735139.1 556566714 17444486 4175286..4175846 1 NC_022657.1 hypothetical protein 4175846 17444486 AFR_19070 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735139.1 4175286 D 1246995 CDS YP_008735140.1 556566715 17444487 4175843..4176520 1 NC_022657.1 hypothetical protein 4176520 17444487 AFR_19075 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735140.1 4175843 D 1246995 CDS YP_008735141.1 556566716 17444488 4176558..4177304 1 NC_022657.1 COG1409 Predicted phosphohydrolases; metallophosphoesterase 4177304 17444488 AFR_19080 Actinoplanes friuliensis DSM 7358 metallophosphoesterase YP_008735141.1 4176558 D 1246995 CDS YP_008735142.1 556566717 17444489 complement(4177314..4178708) 1 NC_022657.1 COG0364 Glucose-6-phosphate 1-dehydrogenase; glucose-6-phosphate 1-dehydrogenase 4178708 17444489 AFR_19085 Actinoplanes friuliensis DSM 7358 glucose-6-phosphate 1-dehydrogenase YP_008735142.1 4177314 R 1246995 CDS YP_008735143.1 556566718 17444490 4178901..4179701 1 NC_022657.1 hypothetical protein 4179701 17444490 AFR_19090 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735143.1 4178901 D 1246995 CDS YP_008735144.1 556566719 17444491 4180043..4180996 1 NC_022657.1 COG4977 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain; HTH-type transcriptional regulator glxA 4180996 17444491 AFR_19095 Actinoplanes friuliensis DSM 7358 HTH-type transcriptional regulator glxA YP_008735144.1 4180043 D 1246995 CDS YP_008735145.1 556566720 17444492 complement(4180977..4181390) 1 NC_022657.1 hypothetical protein 4181390 17444492 AFR_19100 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735145.1 4180977 R 1246995 CDS YP_008735146.1 556566721 17444493 complement(4181387..4182208) 1 NC_022657.1 COG1409 Predicted phosphohydrolases; metallophosphoesterase 4182208 17444493 AFR_19105 Actinoplanes friuliensis DSM 7358 metallophosphoesterase YP_008735146.1 4181387 R 1246995 CDS YP_008735147.1 556566722 17444495 4182427..4182735 1 NC_022657.1 hypothetical protein 4182735 17444495 AFR_19110 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735147.1 4182427 D 1246995 CDS YP_008735148.1 556566723 17444496 4182980..4183462 1 NC_022657.1 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; regulatory protein 4183462 17444496 AFR_19115 Actinoplanes friuliensis DSM 7358 regulatory protein YP_008735148.1 4182980 D 1246995 CDS YP_008735149.1 556566724 17444497 4183462..4185522 1 NC_022657.1 COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain; diguanylate cyclase/phosphodiesterase 4185522 17444497 AFR_19120 Actinoplanes friuliensis DSM 7358 diguanylate cyclase/phosphodiesterase YP_008735149.1 4183462 D 1246995 CDS YP_008735150.1 556566725 17444498 4185552..4186343 1 NC_022657.1 hypothetical protein 4186343 17444498 AFR_19125 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735150.1 4185552 D 1246995 CDS YP_008735151.1 556566726 17444499 complement(4186983..4187210) 1 NC_022657.1 COG1594 DNA-directed RNA polymerase, subunit M/Transcription elongation factor TFIIS; hypothetical protein 4187210 17444499 AFR_19130 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735151.1 4186983 R 1246995 CDS YP_008735152.1 556566727 17444500 complement(4187220..4188254) 1 NC_022657.1 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases; putative luciferase-like monooxygenase 4188254 17444500 AFR_19135 Actinoplanes friuliensis DSM 7358 putative luciferase-like monooxygenase YP_008735152.1 4187220 R 1246995 CDS YP_008735153.1 556566728 17444501 complement(4188283..4189170) 1 NC_022657.1 COG2207 AraC-type DNA-binding domain-containing proteins; Shy25-AraC-family transcriptional regulator 4189170 17444501 AFR_19140 Actinoplanes friuliensis DSM 7358 Shy25-AraC-family transcriptional regulator YP_008735153.1 4188283 R 1246995 CDS YP_008735154.1 556566729 17444502 4189294..4190376 1 NC_022657.1 COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases); aldo/keto reductase 4190376 17444502 AFR_19145 Actinoplanes friuliensis DSM 7358 aldo/keto reductase YP_008735154.1 4189294 D 1246995 CDS YP_008735155.1 556566730 17444503 4190577..4191287 1 NC_022657.1 hypothetical protein 4191287 17444503 AFR_19150 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735155.1 4190577 D 1246995 CDS YP_008735156.1 556566731 17444504 4191302..4192567 1 NC_022657.1 COG3733 Cu2+-containing amine oxidase; primary-amine oxidase 4192567 17444504 AFR_19155 Actinoplanes friuliensis DSM 7358 primary-amine oxidase YP_008735156.1 4191302 D 1246995 CDS YP_008735157.1 556566732 17444505 4192650..4193216 1 NC_022657.1 COG3544 Uncharacterized protein conserved in bacteria; hypothetical protein 4193216 17444505 AFR_19160 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735157.1 4192650 D 1246995 CDS YP_008735158.1 556566733 17444506 complement(4193197..4195428) 1 NC_022657.1 COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain; putative diguanylate cyclase/phosphodiesterase with PAS sensor 4195428 17444506 AFR_19165 Actinoplanes friuliensis DSM 7358 putative diguanylate cyclase/phosphodiesterase with PAS sensor YP_008735158.1 4193197 R 1246995 CDS YP_008735159.1 556566734 17444507 4195547..4198285 1 NC_022657.1 hypothetical protein 4198285 17444507 AFR_19170 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735159.1 4195547 D 1246995 CDS YP_008735160.1 556566735 17444508 complement(4198301..4199368) 1 NC_022657.1 hypothetical protein 4199368 17444508 AFR_19175 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735160.1 4198301 R 1246995 CDS YP_008735161.1 556566736 17444509 4199528..4200472 1 NC_022657.1 COG1816 Adenosine deaminase; adenosine deaminase 4200472 17444509 AFR_19180 Actinoplanes friuliensis DSM 7358 adenosine deaminase YP_008735161.1 4199528 D 1246995 CDS YP_008735162.1 556566737 17444510 4200563..4200832 1 NC_022657.1 COG1987 Flagellar biosynthesis pathway, component FliQ; Flagellar biosynthetic protein fliQ 4200832 17444510 AFR_19185 Actinoplanes friuliensis DSM 7358 Flagellar biosynthetic protein fliQ YP_008735162.1 4200563 D 1246995 CDS YP_008735163.1 556566738 17444511 complement(4200876..4202129) 1 NC_022657.1 COG2039 Pyrrolidone-carboxylate peptidase (N-terminal pyroglutamyl peptidase); hypothetical protein 4202129 17444511 AFR_19190 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735163.1 4200876 R 1246995 CDS YP_008735164.1 556566739 17444512 complement(4202167..4202844) 1 NC_022657.1 COG3382 Uncharacterized conserved protein; hypothetical protein 4202844 17444512 AFR_19195 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735164.1 4202167 R 1246995 CDS YP_008735165.1 556566740 17444513 complement(4202841..4203782) 1 NC_022657.1 hypothetical protein 4203782 17444513 AFR_19200 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735165.1 4202841 R 1246995 CDS YP_008735166.1 556566741 17444514 4203790..4205232 1 NC_022657.1 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs; GntR family transcriptional regulator 4205232 17444514 AFR_19205 Actinoplanes friuliensis DSM 7358 GntR family transcriptional regulator YP_008735166.1 4203790 D 1246995 CDS YP_008735167.1 556566742 17444515 complement(4205243..4206196) 1 NC_022657.1 hypothetical protein 4206196 17444515 AFR_19210 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735167.1 4205243 R 1246995 CDS YP_008735168.1 556566743 17444516 complement(4206228..4206524) 1 NC_022657.1 hypothetical protein 4206524 17444516 AFR_19215 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735168.1 4206228 R 1246995 CDS YP_008735169.1 556566744 17444517 complement(4206533..4206910) 1 NC_022657.1 COG0720 6-pyruvoyl-tetrahydropterin synthase; hypothetical protein 4206910 17444517 AFR_19220 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735169.1 4206533 R 1246995 CDS YP_008735170.1 556566745 17444518 complement(4206915..4207469) 1 NC_022657.1 hypothetical protein 4207469 17444518 AFR_19225 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735170.1 4206915 R 1246995 CDS YP_008735171.1 556566746 17444519 complement(4207466..4208818) 1 NC_022657.1 COG0642 Signal transduction histidine kinase; ATPase domain-containing protein 4208818 17444519 AFR_19230 Actinoplanes friuliensis DSM 7358 ATPase domain-containing protein YP_008735171.1 4207466 R 1246995 CDS YP_008735172.1 556566747 17444520 complement(4208815..4209483) 1 NC_022657.1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; winged helix family two component transcriptional regulator 4209483 17444520 AFR_19235 Actinoplanes friuliensis DSM 7358 winged helix family two component transcriptional regulator YP_008735172.1 4208815 R 1246995 CDS YP_008735173.1 556566748 17444521 4209617..4209922 1 NC_022657.1 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); anti-sigma-factor antagonist 4209922 17444521 AFR_19240 Actinoplanes friuliensis DSM 7358 anti-sigma-factor antagonist YP_008735173.1 4209617 D 1246995 CDS YP_008735174.1 556566749 17444522 4209919..4210278 1 NC_022657.1 hypothetical protein 4210278 17444522 AFR_19245 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735174.1 4209919 D 1246995 CDS YP_008735175.1 556566750 17444523 4210586..4211641 1 NC_022657.1 COG2199 FOG: GGDEF domain; PAS/PAC and GAF sensor-containing diguanylate cyclase 4211641 17444523 AFR_19250 Actinoplanes friuliensis DSM 7358 PAS/PAC and GAF sensor-containing diguanylate cyclase YP_008735175.1 4210586 D 1246995 CDS YP_008735176.1 556566751 17444524 complement(4211622..4212419) 1 NC_022657.1 COG1414 Transcriptional regulator; putative IclR-family transcriptional regulator 4212419 17444524 AFR_19255 Actinoplanes friuliensis DSM 7358 putative IclR-family transcriptional regulator YP_008735176.1 4211622 R 1246995 CDS YP_008735177.1 556566752 17444525 complement(4212424..4212804) 1 NC_022657.1 COG0599 Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit; 3-oxoadipate enol-lactonase 4212804 17444525 AFR_19260 Actinoplanes friuliensis DSM 7358 3-oxoadipate enol-lactonase YP_008735177.1 4212424 R 1246995 CDS YP_008735178.1 556566753 17444526 complement(4212797..4213558) 1 NC_022657.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); 3-oxoadipate enol-lactonase 4213558 17444526 AFR_19265 Actinoplanes friuliensis DSM 7358 3-oxoadipate enol-lactonase YP_008735178.1 4212797 R 1246995 CDS YP_008735179.1 556566754 17444527 complement(4213555..4215030) 1 NC_022657.1 COG0015 Adenylosuccinate lyase; 3-carboxy-cis,cis-muconate cycloisomerase 4215030 17444527 AFR_19270 Actinoplanes friuliensis DSM 7358 3-carboxy-cis,cis-muconate cycloisomerase YP_008735179.1 4213555 R 1246995 CDS YP_008735180.1 556566755 17444528 complement(4215005..4215508) 1 NC_022657.1 COG3485 Protocatechuate 3,4-dioxygenase beta subunit; protocatechuate 3,4-dioxygenase subunit alpha 4215508 17444528 AFR_19275 Actinoplanes friuliensis DSM 7358 protocatechuate 3,4-dioxygenase subunit alpha YP_008735180.1 4215005 R 1246995 CDS YP_008735181.1 556566756 17444529 complement(4215505..4216176) 1 NC_022657.1 COG3485 Protocatechuate 3,4-dioxygenase beta subunit; protocatechuate 3,4-dioxygenase beta subunit 4216176 17444529 AFR_19280 Actinoplanes friuliensis DSM 7358 protocatechuate 3,4-dioxygenase beta subunit YP_008735181.1 4215505 R 1246995 CDS YP_008735182.1 556566757 17444530 complement(4216173..4216931) 1 NC_022657.1 COG2057 Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit; acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit 4216931 17444530 AFR_19285 Actinoplanes friuliensis DSM 7358 acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit YP_008735182.1 4216173 R 1246995 CDS YP_008735183.1 556566758 17444531 complement(4216928..4217731) 1 NC_022657.1 COG1788 Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit; 3-oxoadipate:succinyl-CoA transferase subunit A 4217731 17444531 AFR_19290 Actinoplanes friuliensis DSM 7358 3-oxoadipate:succinyl-CoA transferase subunit A YP_008735183.1 4216928 R 1246995 CDS YP_008735184.1 556566759 17444532 complement(4217728..4218867) 1 NC_022657.1 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases; 4-hydroxybenzoate 3-monooxygenase 4218867 17444532 AFR_19295 Actinoplanes friuliensis DSM 7358 4-hydroxybenzoate 3-monooxygenase YP_008735184.1 4217728 R 1246995 CDS YP_008735185.1 556566760 17444533 4218990..4219955 1 NC_022657.1 COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components; putative ABC transporter substrate-binding protein 4219955 17444533 AFR_19300 Actinoplanes friuliensis DSM 7358 putative ABC transporter substrate-binding protein YP_008735185.1 4218990 D 1246995 CDS YP_008735186.1 556566761 17444534 4219952..4220743 1 NC_022657.1 COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component; Putative aliphatic sulfonates transport permease protein ssuC 4220743 17444534 AFR_19305 Actinoplanes friuliensis DSM 7358 Putative aliphatic sulfonates transport permease protein ssuC YP_008735186.1 4219952 D 1246995 CDS YP_008735187.1 556566762 17444535 4220740..4221594 1 NC_022657.1 COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component; Bicarbonate transport system permease protein cmpB 4221594 17444535 AFR_19310 Actinoplanes friuliensis DSM 7358 Bicarbonate transport system permease protein cmpB YP_008735187.1 4220740 D 1246995 CDS YP_008735188.1 556566763 17444536 4221609..4222406 1 NC_022657.1 COG1116 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component; spermidine/putrescine import ATP-binding protein potA 4222406 17444536 AFR_19315 Actinoplanes friuliensis DSM 7358 spermidine/putrescine import ATP-binding protein potA YP_008735188.1 4221609 D 1246995 CDS YP_008735189.1 556566764 17444537 complement(4222351..4223811) 1 NC_022657.1 COG1012 NAD-dependent aldehyde dehydrogenases; aldehyde dehydrogenase 4223811 17444537 AFR_19320 Actinoplanes friuliensis DSM 7358 aldehyde dehydrogenase YP_008735189.1 4222351 R 1246995 CDS YP_008735190.1 556566765 17444538 complement(4223910..4224815) 1 NC_022657.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); epoxide hydrolase 4224815 17444538 AFR_19325 Actinoplanes friuliensis DSM 7358 epoxide hydrolase YP_008735190.1 4223910 R 1246995 CDS YP_008735191.1 556566766 17444539 4224879..4226534 1 NC_022657.1 COG2378 Predicted transcriptional regulator; DeoR family transcriptional regulator 4226534 17444539 AFR_19330 Actinoplanes friuliensis DSM 7358 DeoR family transcriptional regulator YP_008735191.1 4224879 D 1246995 CDS YP_008735192.1 556566767 17444540 complement(4225830..4226657) 1 NC_022657.1 COG0395 ABC-type sugar transport system, permease component; binding-protein-dependent transport systems inner membrane component 4226657 17444540 AFR_19335 Actinoplanes friuliensis DSM 7358 binding-protein-dependent transport systems inner membrane component YP_008735192.1 4225830 R 1246995 CDS YP_008735193.1 556566768 17444541 complement(4226654..4227520) 1 NC_022657.1 COG1175 ABC-type sugar transport systems, permease components; binding-protein-dependent transport systems inner membrane component 4227520 17444541 AFR_19340 Actinoplanes friuliensis DSM 7358 binding-protein-dependent transport systems inner membrane component YP_008735193.1 4226654 R 1246995 CDS YP_008735194.1 556566769 17444542 complement(4227526..4228839) 1 NC_022657.1 COG1653 ABC-type sugar transport system, periplasmic component; extracellular solute-binding protein family 1 protein 4228839 17444542 AFR_19345 Actinoplanes friuliensis DSM 7358 extracellular solute-binding protein family 1 protein YP_008735194.1 4227526 R 1246995 CDS YP_008735195.1 556566770 17444543 complement(4228865..4231627) 1 NC_022657.1 alpha-L-rhamnosidase 4231627 17444543 AFR_19350 Actinoplanes friuliensis DSM 7358 alpha-L-rhamnosidase YP_008735195.1 4228865 R 1246995 CDS YP_008735196.1 556566771 17444544 4231833..4232753 1 NC_022657.1 COG2207 AraC-type DNA-binding domain-containing proteins; AraC family transcriptional regulator 4232753 17444544 AFR_19355 Actinoplanes friuliensis DSM 7358 AraC family transcriptional regulator YP_008735196.1 4231833 D 1246995 CDS YP_008735197.1 556566772 17444545 complement(4232755..4233264) 1 NC_022657.1 hypothetical protein 4233264 17444545 AFR_19360 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735197.1 4232755 R 1246995 CDS YP_008735198.1 556566773 17444546 complement(4233347..4233751) 1 NC_022657.1 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins; GCN5-related N-acetyltransferase 4233751 17444546 AFR_19365 Actinoplanes friuliensis DSM 7358 GCN5-related N-acetyltransferase YP_008735198.1 4233347 R 1246995 CDS YP_008735199.1 556566774 17444547 complement(4233834..4234205) 1 NC_022657.1 hypothetical protein 4234205 17444547 AFR_19370 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735199.1 4233834 R 1246995 CDS YP_008735200.1 556566775 17444548 4234327..4235235 1 NC_022657.1 COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases; D-isomer specific 2-hydroxyacid dehydrogenase 4235235 17444548 AFR_19375 Actinoplanes friuliensis DSM 7358 D-isomer specific 2-hydroxyacid dehydrogenase YP_008735200.1 4234327 D 1246995 CDS YP_008735201.1 556566776 17444549 complement(4235252..4237036) 1 NC_022657.1 COG0366 Glycosidases; alpha-amylase 4237036 17444549 AFR_19380 Actinoplanes friuliensis DSM 7358 alpha-amylase YP_008735201.1 4235252 R 1246995 CDS YP_008735202.1 556566777 17444550 complement(4237298..4238359) 1 NC_022657.1 COG1609 Transcriptional regulators; LacI family transcriptional regulator 4238359 17444550 AFR_19385 Actinoplanes friuliensis DSM 7358 LacI family transcriptional regulator YP_008735202.1 4237298 R 1246995 CDS YP_008735203.1 556566778 17444551 4238524..4239792 1 NC_022657.1 COG2182 Maltose-binding periplasmic proteins/domains; putative ABC transporter substrate-binding protein 4239792 17444551 AFR_19390 Actinoplanes friuliensis DSM 7358 putative ABC transporter substrate-binding protein YP_008735203.1 4238524 D 1246995 CDS YP_008735204.1 556566779 17444552 4239789..4241378 1 NC_022657.1 COG1175 ABC-type sugar transport systems, permease components; ABC transporter permease 4241378 17444552 AFR_19395 Actinoplanes friuliensis DSM 7358 ABC transporter permease YP_008735204.1 4239789 D 1246995 CDS YP_008735205.1 556566780 17444553 4241375..4242220 1 NC_022657.1 COG3833 ABC-type maltose transport systems, permease component; binding-protein-dependent transport systems inner membrane component 4242220 17444553 AFR_19400 Actinoplanes friuliensis DSM 7358 binding-protein-dependent transport systems inner membrane component YP_008735205.1 4241375 D 1246995 CDS YP_008735206.1 556566781 17444554 complement(4242217..4243182) 1 NC_022657.1 COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases; alcohol dehydrogenase 4243182 17444554 AFR_19405 Actinoplanes friuliensis DSM 7358 alcohol dehydrogenase YP_008735206.1 4242217 R 1246995 CDS YP_008735207.1 556566782 17444555 complement(4243211..4244155) 1 NC_022657.1 NADPH:quinone reductase-like protein 4244155 17444555 AFR_19410 Actinoplanes friuliensis DSM 7358 NADPH:quinone reductase-like protein YP_008735207.1 4243211 R 1246995 CDS YP_008735208.1 556566783 17444556 complement(4244152..4244487) 1 NC_022657.1 COG1695 Predicted transcriptional regulators; PadR family transcriptional regulator 4244487 17444556 AFR_19415 Actinoplanes friuliensis DSM 7358 PadR family transcriptional regulator YP_008735208.1 4244152 R 1246995 CDS YP_008735209.1 556566784 17444557 4244628..4245266 1 NC_022657.1 COG1309 Transcriptional regulator; TetR family transcriptional regulator 4245266 17444557 AFR_19420 Actinoplanes friuliensis DSM 7358 TetR family transcriptional regulator YP_008735209.1 4244628 D 1246995 CDS YP_008735210.1 556566785 17444558 complement(4245185..4245583) 1 NC_022657.1 hypothetical protein 4245583 17444558 AFR_19425 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735210.1 4245185 R 1246995 CDS YP_008735211.1 556566786 17444559 4245637..4246053 1 NC_022657.1 COG0863 DNA modification methylase; hypothetical protein 4246053 17444559 AFR_19430 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735211.1 4245637 D 1246995 CDS YP_008735212.1 556566787 17444560 complement(4246058..4247227) 1 NC_022657.1 COG2814 Arabinose efflux permease; major facilitator transporter 4247227 17444560 AFR_19435 Actinoplanes friuliensis DSM 7358 major facilitator transporter YP_008735212.1 4246058 R 1246995 CDS YP_008735213.1 556566788 17444561 4247328..4247762 1 NC_022657.1 COG1846 Transcriptional regulators; MarR family transcriptional regulator 4247762 17444561 AFR_19440 Actinoplanes friuliensis DSM 7358 MarR family transcriptional regulator YP_008735213.1 4247328 D 1246995 CDS YP_008735214.1 556566789 17444562 4247827..4248681 1 NC_022657.1 COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases); oxidoreductase 4248681 17444562 AFR_19445 Actinoplanes friuliensis DSM 7358 oxidoreductase YP_008735214.1 4247827 D 1246995 CDS YP_008735215.1 556566790 17444563 complement(4248678..4250135) 1 NC_022657.1 COG3104 Dipeptide/tripeptide permease; putative oligopeptide transporter 4250135 17444563 AFR_19450 Actinoplanes friuliensis DSM 7358 putative oligopeptide transporter YP_008735215.1 4248678 R 1246995 CDS YP_008735216.1 556566791 17444564 4250243..4252105 1 NC_022657.1 COG3004 Na+/H+ antiporter; sodium/proton antiporter 4252105 17444564 AFR_19455 Actinoplanes friuliensis DSM 7358 sodium/proton antiporter YP_008735216.1 4250243 D 1246995 CDS YP_008735217.1 556566792 17444565 4252171..4253385 1 NC_022657.1 COG1680 Beta-lactamase class C and other penicillin binding proteins; beta-lactamase 4253385 17444565 AFR_19460 Actinoplanes friuliensis DSM 7358 beta-lactamase YP_008735217.1 4252171 D 1246995 CDS YP_008735218.1 556566793 17444566 4253445..4254131 1 NC_022657.1 VanZ family protein 4254131 17444566 AFR_19465 Actinoplanes friuliensis DSM 7358 VanZ family protein YP_008735218.1 4253445 D 1246995 CDS YP_008735219.1 556566794 17444567 4254119..4254790 1 NC_022657.1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; putative two-component system response regulator 4254790 17444567 AFR_19470 Actinoplanes friuliensis DSM 7358 putative two-component system response regulator YP_008735219.1 4254119 D 1246995 CDS YP_008735220.1 556566795 17444568 4254846..4255901 1 NC_022657.1 COG0642 Signal transduction histidine kinase; putative two-component system sensor kinase 4255901 17444568 AFR_19475 Actinoplanes friuliensis DSM 7358 putative two-component system sensor kinase YP_008735220.1 4254846 D 1246995 CDS YP_008735221.1 556566796 17444569 4255906..4256463 1 NC_022657.1 COG0187 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit; hypothetical protein 4256463 17444569 AFR_19480 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735221.1 4255906 D 1246995 CDS YP_008735222.1 556566797 17444570 complement(4256460..4256804) 1 NC_022657.1 COG0346 Lactoylglutathione lyase and related lyases; hypothetical protein 4256804 17444570 AFR_19485 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735222.1 4256460 R 1246995 CDS YP_008735223.1 556566798 17444571 complement(4256801..4257979) 1 NC_022657.1 COG1641 Uncharacterized conserved protein; hypothetical protein 4257979 17444571 AFR_19490 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735223.1 4256801 R 1246995 CDS YP_008735224.1 556566799 17444572 complement(4257976..4258638) 1 NC_022657.1 COG1691 NCAIR mutase (PurE)-related proteins; hypothetical protein 4258638 17444572 AFR_19495 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735224.1 4257976 R 1246995 CDS YP_008735225.1 556566800 17444573 complement(4258631..4259434) 1 NC_022657.1 COG1606 ATP-utilizing enzymes of the PP-loop superfamily; GMP synthase 4259434 17444573 AFR_19500 Actinoplanes friuliensis DSM 7358 GMP synthase YP_008735225.1 4258631 R 1246995 CDS YP_008735226.1 556566801 17444574 4259497..4260552 1 NC_022657.1 COG1609 Transcriptional regulators; LacI family transcriptional regulator 4260552 17444574 AFR_19505 Actinoplanes friuliensis DSM 7358 LacI family transcriptional regulator YP_008735226.1 4259497 D 1246995 CDS YP_008735227.1 556566802 17444575 complement(4260876..4271285) 1 NC_022657.1 hypothetical protein 4271285 17444575 AFR_19510 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735227.1 4260876 R 1246995 CDS YP_008735228.1 556566803 17444576 complement(4271414..4271923) 1 NC_022657.1 COG1309 Transcriptional regulator; HTH-type transcriptional regulator betI 4271923 17444576 AFR_19515 Actinoplanes friuliensis DSM 7358 HTH-type transcriptional regulator betI YP_008735228.1 4271414 R 1246995 CDS YP_008735229.1 556566804 17444577 4272046..4273227 1 NC_022657.1 COG0183 Acetyl-CoA acetyltransferase; acetyl-CoA acyltransferase 4273227 17444577 AFR_19520 Actinoplanes friuliensis DSM 7358 acetyl-CoA acyltransferase YP_008735229.1 4272046 D 1246995 CDS YP_008735230.1 556566805 17444578 complement(4273208..4273948) 1 NC_022657.1 COG1122 ABC-type cobalt transport system, ATPase component; phosphate import ATP-binding protein pstB 4273948 17444578 AFR_19525 Actinoplanes friuliensis DSM 7358 phosphate import ATP-binding protein pstB YP_008735230.1 4273208 R 1246995 CDS YP_008735231.1 556566806 17444579 complement(4273945..4274706) 1 NC_022657.1 COG0619 ABC-type cobalt transport system, permease component CbiQ and related transporters; cobalt ABC transporter permease 4274706 17444579 AFR_19530 Actinoplanes friuliensis DSM 7358 cobalt ABC transporter permease YP_008735231.1 4273945 R 1246995 CDS YP_008735232.1 556566807 17444580 complement(4274706..4275053) 1 NC_022657.1 hypothetical protein 4275053 17444580 AFR_19535 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735232.1 4274706 R 1246995 CDS YP_008735233.1 556566808 17444581 complement(4275050..4275772) 1 NC_022657.1 COG0310 ABC-type Co2+ transport system, permease component; Protein cbiM 4275772 17444581 AFR_19540 Actinoplanes friuliensis DSM 7358 Protein cbiM YP_008735233.1 4275050 R 1246995 CDS YP_008735234.1 556566809 17444582 complement(4275874..4276740) 1 NC_022657.1 COG0162 Tyrosyl-tRNA synthetase; hypothetical protein 4276740 17444582 AFR_19545 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735234.1 4275874 R 1246995 CDS YP_008735235.1 556566810 17444583 complement(4276755..4277936) 1 NC_022657.1 hypothetical protein 4277936 17444583 AFR_19550 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735235.1 4276755 R 1246995 CDS YP_008735236.1 556566811 17444584 complement(4278056..4279003) 1 NC_022657.1 COG3640 CO dehydrogenase maturation factor; ATP-binding protein 4279003 17444584 AFR_19555 Actinoplanes friuliensis DSM 7358 ATP-binding protein YP_008735236.1 4278056 R 1246995 CDS YP_008735237.1 556566812 17444585 4279082..4279558 1 NC_022657.1 hypothetical protein 4279558 17444585 AFR_19560 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735237.1 4279082 D 1246995 CDS YP_008735238.1 556566813 17444586 complement(4279566..4280048) 1 NC_022657.1 COG0691 tmRNA-binding protein; SsrA-binding protein 4280048 smpB 17444586 smpB Actinoplanes friuliensis DSM 7358 SsrA-binding protein YP_008735238.1 4279566 R 1246995 CDS YP_008735239.1 556566814 17444587 4280245..4280571 1 NC_022657.1 COG1359 Uncharacterized conserved protein; putative antibiotic biosynthesis monooxygenase 4280571 17444587 AFR_19570 Actinoplanes friuliensis DSM 7358 putative antibiotic biosynthesis monooxygenase YP_008735239.1 4280245 D 1246995 CDS YP_008735240.1 556566815 17444588 complement(4280614..4281735) 1 NC_022657.1 COG2755 Lysophospholipase L1 and related esterases; putative GDSL-like lipase/acylhydrolase with Cellulose binding domain 4281735 17444588 AFR_19575 Actinoplanes friuliensis DSM 7358 putative GDSL-like lipase/acylhydrolase with Cellulose binding domain YP_008735240.1 4280614 R 1246995 CDS YP_008735241.1 556566816 17444589 4281929..4284118 1 NC_022657.1 cellulose-binding family II 4284118 17444589 AFR_19580 Actinoplanes friuliensis DSM 7358 cellulose-binding family II YP_008735241.1 4281929 D 1246995 CDS YP_008735242.1 556566817 17444590 complement(4284105..4284644) 1 NC_022657.1 hypothetical protein 4284644 17444590 AFR_19585 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735242.1 4284105 R 1246995 CDS YP_008735243.1 556566818 17444591 4284712..4285248 1 NC_022657.1 COG1309 Transcriptional regulator; putative TetR-family transcriptional regulator 4285248 17444591 AFR_19590 Actinoplanes friuliensis DSM 7358 putative TetR-family transcriptional regulator YP_008735243.1 4284712 D 1246995 CDS YP_008735244.1 556566819 17444592 complement(4285239..4286594) 1 NC_022657.1 COG0247 Fe-S oxidoreductase; hypothetical protein 4286594 17444592 AFR_19595 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735244.1 4285239 R 1246995 CDS YP_008735245.1 556566820 17444593 complement(4286594..4287739) 1 NC_022657.1 COG0277 FAD/FMN-containing dehydrogenases; glycolate oxidase FAD binding subunit 4287739 17444593 AFR_19600 Actinoplanes friuliensis DSM 7358 glycolate oxidase FAD binding subunit YP_008735245.1 4286594 R 1246995 CDS YP_008735246.1 556566821 17444594 complement(4287739..4289187) 1 NC_022657.1 COG0277 FAD/FMN-containing dehydrogenases; putative FAD linked oxidase 4289187 17444594 AFR_19605 Actinoplanes friuliensis DSM 7358 putative FAD linked oxidase YP_008735246.1 4287739 R 1246995 CDS YP_008735247.1 556566822 17444595 4289330..4292203 1 NC_022657.1 putative metallopeptidase 4292203 17444595 AFR_19610 Actinoplanes friuliensis DSM 7358 putative metallopeptidase YP_008735247.1 4289330 D 1246995 CDS YP_008735248.1 556566823 17444596 4292335..4293348 1 NC_022657.1 COG5563 Predicted integral membrane proteins containing uncharacterized repeats; extracellular repeat-containing protein, HAF family 4293348 17444596 AFR_19615 Actinoplanes friuliensis DSM 7358 extracellular repeat-containing protein, HAF family YP_008735248.1 4292335 D 1246995 CDS YP_008735249.1 556566824 17444597 4293395..4294642 1 NC_022657.1 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases; putative alcohol dehydrogenase 4294642 17444597 AFR_19620 Actinoplanes friuliensis DSM 7358 putative alcohol dehydrogenase YP_008735249.1 4293395 D 1246995 CDS YP_008735250.1 556566825 17444598 4294871..4295107 1 NC_022657.1 hypothetical protein 4295107 17444598 AFR_19625 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735250.1 4294871 D 1246995 CDS YP_008735251.1 556566826 17444599 complement(4295127..4295396) 1 NC_022657.1 hypothetical protein 4295396 17444599 AFR_19630 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735251.1 4295127 R 1246995 CDS YP_008735252.1 556566827 17444600 complement(4295460..4297022) 1 NC_022657.1 COG3227 Zinc metalloprotease (elastase); neutral zinc metalloprotease 4297022 17444600 AFR_19635 Actinoplanes friuliensis DSM 7358 neutral zinc metalloprotease YP_008735252.1 4295460 R 1246995 CDS YP_008735253.1 556566828 17444601 4297208..4298209 1 NC_022657.1 COG0332 3-oxoacyl-[acyl-carrier-protein] synthase III; 3-oxoacyl-(acyl-carrier-protein) synthase III 4298209 17444601 AFR_19640 Actinoplanes friuliensis DSM 7358 3-oxoacyl-(acyl-carrier-protein) synthase III YP_008735253.1 4297208 D 1246995 CDS YP_008735254.1 556566829 17444602 complement(4298206..4298964) 1 NC_022657.1 polymorphic membrane protein 4298964 17444602 AFR_19645 Actinoplanes friuliensis DSM 7358 polymorphic membrane protein YP_008735254.1 4298206 R 1246995 CDS YP_008735255.1 556566830 17444603 4298966..4299367 1 NC_022657.1 hypothetical protein 4299367 17444603 AFR_19650 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735255.1 4298966 D 1246995 CDS YP_008735256.1 556566831 17444604 4299453..4299809 1 NC_022657.1 COG3795 Uncharacterized protein conserved in bacteria; hypothetical protein 4299809 17444604 AFR_19655 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735256.1 4299453 D 1246995 CDS YP_008735257.1 556566832 17444605 4299863..4301020 1 NC_022657.1 COG4941 Predicted RNA polymerase sigma factor containing a TPR repeat domain; putative RNA polymerase ECF-subfamily sigma factor 4301020 17444605 AFR_19660 Actinoplanes friuliensis DSM 7358 putative RNA polymerase ECF-subfamily sigma factor YP_008735257.1 4299863 D 1246995 CDS YP_008735258.1 556566833 17444606 complement(4301017..4301853) 1 NC_022657.1 COG0435 Predicted glutathione S-transferase; glutathione S-transferase domain protein 4301853 17444606 AFR_19665 Actinoplanes friuliensis DSM 7358 glutathione S-transferase domain protein YP_008735258.1 4301017 R 1246995 CDS YP_008735259.1 556566834 17444607 complement(4301864..4303087) 1 NC_022657.1 COG3434 Predicted signal transduction protein containing EAL and modified HD-GYP domains; hypothetical protein 4303087 17444607 AFR_19670 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735259.1 4301864 R 1246995 CDS YP_008735260.1 556566835 17444608 complement(4303152..4303976) 1 NC_022657.1 COG0500 SAM-dependent methyltransferases; methyltransferase type 12 4303976 17444608 AFR_19675 Actinoplanes friuliensis DSM 7358 methyltransferase type 12 YP_008735260.1 4303152 R 1246995 CDS YP_008735261.1 556566836 17444609 complement(4303976..4304338) 1 NC_022657.1 hypothetical protein 4304338 17444609 AFR_19680 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735261.1 4303976 R 1246995 CDS YP_008735262.1 556566837 17444610 complement(4304360..4305190) 1 NC_022657.1 COG0451 Nucleoside-diphosphate-sugar epimerases; NAD-dependent epimerase/dehydratase 4305190 17444610 AFR_19685 Actinoplanes friuliensis DSM 7358 NAD-dependent epimerase/dehydratase YP_008735262.1 4304360 R 1246995 CDS YP_008735263.1 556566838 17444611 complement(4306120..4307961) 1 NC_022657.1 COG0514 Superfamily II DNA helicase; ATP-dependent DNA helicase RecQ 4307961 17444611 AFR_19690 Actinoplanes friuliensis DSM 7358 ATP-dependent DNA helicase RecQ YP_008735263.1 4306120 R 1246995 CDS YP_008735264.1 556566839 17444612 complement(4307958..4309076) 1 NC_022657.1 hypothetical protein 4309076 17444612 AFR_19695 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735264.1 4307958 R 1246995 CDS YP_008735265.1 556566840 17444613 complement(4309073..4310356) 1 NC_022657.1 hypothetical protein 4310356 17444613 AFR_19700 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735265.1 4309073 R 1246995 CDS YP_008735266.1 556566841 17444614 4310509..4311858 1 NC_022657.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); tap domain-containing protein 4311858 17444614 AFR_19705 Actinoplanes friuliensis DSM 7358 tap domain-containing protein YP_008735266.1 4310509 D 1246995 CDS YP_008735267.1 556566842 17444615 complement(4311804..4313771) 1 NC_022657.1 COG2202 FOG: PAS/PAC domain; regulator of sigma subunit, anti-anti-sigma factor RsbU 4313771 17444615 AFR_19710 Actinoplanes friuliensis DSM 7358 regulator of sigma subunit, anti-anti-sigma factor RsbU YP_008735267.1 4311804 R 1246995 CDS YP_008735268.1 556566843 17444616 complement(4313914..4314561) 1 NC_022657.1 COG0807 GTP cyclohydrolase II; putative GTP cyclohydrolase II 4314561 17444616 AFR_19715 Actinoplanes friuliensis DSM 7358 putative GTP cyclohydrolase II YP_008735268.1 4313914 R 1246995 CDS YP_008735269.1 556566844 17444617 complement(4314603..4315256) 1 NC_022657.1 COG1985 Pyrimidine reductase, riboflavin biosynthesis; 5-amino-6-(5-phosphoribosylamino)uracil reductase 4315256 17444617 AFR_19720 Actinoplanes friuliensis DSM 7358 5-amino-6-(5-phosphoribosylamino)uracil reductase YP_008735269.1 4314603 R 1246995 CDS YP_008735270.1 556566845 17444618 complement(4315366..4316424) 1 NC_022657.1 hypothetical protein 4316424 17444618 AFR_19725 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735270.1 4315366 R 1246995 CDS YP_008735271.1 556566846 17444619 complement(4316485..4317288) 1 NC_022657.1 hypothetical protein 4317288 17444619 AFR_19730 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735271.1 4316485 R 1246995 CDS YP_008735272.1 556566847 17444620 complement(4317285..4318364) 1 NC_022657.1 COG0438 Glycosyltransferase; group 1 glycosyl transferase 4318364 17444620 AFR_19735 Actinoplanes friuliensis DSM 7358 group 1 glycosyl transferase YP_008735272.1 4317285 R 1246995 CDS YP_008735273.1 556566848 17444621 complement(4318361..4318759) 1 NC_022657.1 COG0720 6-pyruvoyl-tetrahydropterin synthase; hypothetical protein 4318759 17444621 AFR_19740 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735273.1 4318361 R 1246995 CDS YP_008735274.1 556566849 17444622 complement(4318760..4319743) 1 NC_022657.1 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases; alcohol dehydrogenase 4319743 17444622 AFR_19745 Actinoplanes friuliensis DSM 7358 alcohol dehydrogenase YP_008735274.1 4318760 R 1246995 CDS YP_008735275.1 556566850 17444623 4319870..4320655 1 NC_022657.1 COG0558 Phosphatidylglycerophosphate synthase; putative CDP-alcohol phosphatidyltransferase 4320655 17444623 AFR_19750 Actinoplanes friuliensis DSM 7358 putative CDP-alcohol phosphatidyltransferase YP_008735275.1 4319870 D 1246995 CDS YP_008735276.1 556566851 17444624 complement(4320658..4321542) 1 NC_022657.1 COG0614 ABC-type Fe3+-hydroxamate transport system, periplasmic component; vitamin B12-binding protein 4321542 17444624 AFR_19755 Actinoplanes friuliensis DSM 7358 vitamin B12-binding protein YP_008735276.1 4320658 R 1246995 CDS YP_008735277.1 556566852 17444625 complement(4321545..4322372) 1 NC_022657.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); hypothetical protein 4322372 17444625 AFR_19760 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735277.1 4321545 R 1246995 CDS YP_008735278.1 556566853 17444626 complement(4322442..4323197) 1 NC_022657.1 COG0627 Predicted esterase; putative esterase 4323197 17444626 AFR_19765 Actinoplanes friuliensis DSM 7358 putative esterase YP_008735278.1 4322442 R 1246995 CDS YP_008735279.1 556566854 17444627 4323427..4323642 1 NC_022657.1 hypothetical protein 4323642 17444627 AFR_19770 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735279.1 4323427 D 1246995 CDS YP_008735280.1 556566855 17444628 4323717..4325096 1 NC_022657.1 COG2233 Xanthine/uracil permeases; xanthine/uracil permease 4325096 17444628 AFR_19775 Actinoplanes friuliensis DSM 7358 xanthine/uracil permease YP_008735280.1 4323717 D 1246995 CDS YP_008735281.1 556566856 17444629 complement(4325228..4325587) 1 NC_022657.1 hypothetical protein 4325587 17444629 AFR_19780 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735281.1 4325228 R 1246995 CDS YP_008735282.1 556566857 17444630 complement(4325612..4326523) 1 NC_022657.1 COG0789 Predicted transcriptional regulators; transcriptional regulator, MerR family protein 4326523 17444630 AFR_19785 Actinoplanes friuliensis DSM 7358 transcriptional regulator, MerR family protein YP_008735282.1 4325612 R 1246995 CDS YP_008735283.1 556566858 17444631 4326601..4327062 1 NC_022657.1 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; GCN5-like N-acetyltransferase 4327062 17444631 AFR_19790 Actinoplanes friuliensis DSM 7358 GCN5-like N-acetyltransferase YP_008735283.1 4326601 D 1246995 CDS YP_008735284.1 556566859 17444632 complement(4327050..4327835) 1 NC_022657.1 COG3386 Gluconolactonase; SMP-30/gluconolaconase/LRE-like region-containing protein 4327835 17444632 AFR_19795 Actinoplanes friuliensis DSM 7358 SMP-30/gluconolaconase/LRE-like region-containing protein YP_008735284.1 4327050 R 1246995 CDS YP_008735285.1 556566860 17444633 4327869..4328300 1 NC_022657.1 COG4405 Uncharacterized protein conserved in bacteria; hypothetical protein 4328300 17444633 AFR_19800 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735285.1 4327869 D 1246995 CDS YP_008735286.1 556566861 17444634 complement(4328284..4329588) 1 NC_022657.1 hypothetical protein 4329588 17444634 AFR_19805 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735286.1 4328284 R 1246995 CDS YP_008735287.1 556566862 17444635 complement(4329753..4330253) 1 NC_022657.1 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins; acetyltransferase 4330253 17444635 AFR_19810 Actinoplanes friuliensis DSM 7358 acetyltransferase YP_008735287.1 4329753 R 1246995 CDS YP_008735288.1 556566863 17444636 complement(4330258..4331616) 1 NC_022657.1 COG4097 Predicted ferric reductase; putative oxidoreductase 4331616 17444636 AFR_19815 Actinoplanes friuliensis DSM 7358 putative oxidoreductase YP_008735288.1 4330258 R 1246995 CDS YP_008735289.1 556566864 17444637 4331823..4333649 1 NC_022657.1 COG0326 Molecular chaperone, HSP90 family; heat shock protein 90 4333649 17444637 AFR_19820 Actinoplanes friuliensis DSM 7358 heat shock protein 90 YP_008735289.1 4331823 D 1246995 CDS YP_008735290.1 556566865 17444638 complement(4333646..4334152) 1 NC_022657.1 COG1309 Transcriptional regulator; TetR family transcriptional regulator 4334152 17444638 AFR_19825 Actinoplanes friuliensis DSM 7358 TetR family transcriptional regulator YP_008735290.1 4333646 R 1246995 CDS YP_008735291.1 556566866 17444639 4334212..4335222 1 NC_022657.1 COG2130 Putative NADP-dependent oxidoreductases; NADP-dependent oxidoreductase 4335222 17444639 AFR_19830 Actinoplanes friuliensis DSM 7358 NADP-dependent oxidoreductase YP_008735291.1 4334212 D 1246995 CDS YP_008735292.1 556566867 17444640 complement(4335283..4336146) 1 NC_022657.1 COG1073 Hydrolases of the alpha/beta superfamily; triacylglycerol lipase 4336146 17444640 AFR_19835 Actinoplanes friuliensis DSM 7358 triacylglycerol lipase YP_008735292.1 4335283 R 1246995 CDS YP_008735293.1 556566868 17444641 complement(4336276..4336659) 1 NC_022657.1 COG1846 Transcriptional regulators; MarR family transcriptional regulator 4336659 17444641 AFR_19840 Actinoplanes friuliensis DSM 7358 MarR family transcriptional regulator YP_008735293.1 4336276 R 1246995 CDS YP_008735294.1 556566869 17444642 4336824..4338170 1 NC_022657.1 COG0477 Permeases of the major facilitator superfamily; multidrug ABC transporter 4338170 17444642 AFR_19845 Actinoplanes friuliensis DSM 7358 multidrug ABC transporter YP_008735294.1 4336824 D 1246995 CDS YP_008735295.1 556566870 17444643 4338213..4339295 1 NC_022657.1 hypothetical protein 4339295 17444643 AFR_19850 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735295.1 4338213 D 1246995 CDS YP_008735296.1 556566871 17444644 4339342..4340403 1 NC_022657.1 hypothetical protein 4340403 17444644 AFR_19855 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735296.1 4339342 D 1246995 CDS YP_008735297.1 556566872 17444645 4340455..4341534 1 NC_022657.1 hypothetical protein 4341534 17444645 AFR_19860 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735297.1 4340455 D 1246995 CDS YP_008735298.1 556566873 17444646 complement(4341785..4342924) 1 NC_022657.1 COG0524 Sugar kinases, ribokinase family; putative PfkB-family carbohydrate kinase 4342924 17444646 AFR_19865 Actinoplanes friuliensis DSM 7358 putative PfkB-family carbohydrate kinase YP_008735298.1 4341785 R 1246995 CDS YP_008735299.1 556566874 17444647 complement(4342935..4343090) 1 NC_022657.1 hypothetical protein 4343090 17444647 AFR_19870 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735299.1 4342935 R 1246995 CDS YP_008735300.1 556566875 17444648 complement(4343171..4344043) 1 NC_022657.1 COG2159 Predicted metal-dependent hydrolase of the TIM-barrel fold; amidohydrolase family protein 4344043 17444648 AFR_19875 Actinoplanes friuliensis DSM 7358 amidohydrolase family protein YP_008735300.1 4343171 R 1246995 CDS YP_008735301.1 556566876 17444649 4344096..4345640 1 NC_022657.1 COG0477 Permeases of the major facilitator superfamily; putative MFS transporter 4345640 17444649 AFR_19880 Actinoplanes friuliensis DSM 7358 putative MFS transporter YP_008735301.1 4344096 D 1246995 CDS YP_008735302.1 556566877 17444650 4345637..4346236 1 NC_022657.1 COG1309 Transcriptional regulator; HTH-type transcriptional regulator tcmR 4346236 17444650 AFR_19885 Actinoplanes friuliensis DSM 7358 HTH-type transcriptional regulator tcmR YP_008735302.1 4345637 D 1246995 CDS YP_008735303.1 556566878 17444651 complement(4346233..4346811) 1 NC_022657.1 COG1309 Transcriptional regulator; Transcriptional regulator, TetR family protein 4346811 17444651 AFR_19890 Actinoplanes friuliensis DSM 7358 Transcriptional regulator, TetR family protein YP_008735303.1 4346233 R 1246995 CDS YP_008735304.1 556566879 17444652 4346893..4347576 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); short chain dehydrogenase 4347576 17444652 AFR_19895 Actinoplanes friuliensis DSM 7358 short chain dehydrogenase YP_008735304.1 4346893 D 1246995 CDS YP_008735305.1 556566880 17444653 4347715..4349190 1 NC_022657.1 COG2610 H+/gluconate symporter and related permeases; putative gluconate permease 4349190 17444653 AFR_19900 Actinoplanes friuliensis DSM 7358 putative gluconate permease YP_008735305.1 4347715 D 1246995 CDS YP_008735306.1 556566881 17444654 complement(4349227..4351743) 1 NC_022657.1 COG0577 ABC-type antimicrobial peptide transport system, permease component; hypothetical protein 4351743 17444654 AFR_19905 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735306.1 4349227 R 1246995 CDS YP_008735307.1 556566882 17444655 complement(4351743..4352456) 1 NC_022657.1 COG1136 ABC-type antimicrobial peptide transport system, ATPase component; ABC transporter 4352456 17444655 AFR_19910 Actinoplanes friuliensis DSM 7358 ABC transporter YP_008735307.1 4351743 R 1246995 CDS YP_008735308.1 556566883 17444656 complement(4352453..4352638) 1 NC_022657.1 hypothetical protein 4352638 17444656 AFR_19915 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735308.1 4352453 R 1246995 CDS YP_008735309.1 556566884 17444657 4352796..4354028 1 NC_022657.1 COG4564 Signal transduction histidine kinase; integral membrane sensor signal transduction histidine kinase 4354028 17444657 AFR_19920 Actinoplanes friuliensis DSM 7358 integral membrane sensor signal transduction histidine kinase YP_008735309.1 4352796 D 1246995 CDS YP_008735310.1 556566885 17444658 4354016..4354675 1 NC_022657.1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; two-component system response regulator 4354675 17444658 AFR_19925 Actinoplanes friuliensis DSM 7358 two-component system response regulator YP_008735310.1 4354016 D 1246995 CDS YP_008735311.1 556566886 17444659 complement(4354697..4355455) 1 NC_022657.1 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases; flavin-dependent oxidoreductase, F420-dependent methylene-tetrahydromethanopterin reductase 4355455 17444659 AFR_19930 Actinoplanes friuliensis DSM 7358 flavin-dependent oxidoreductase, F420-dependent methylene-tetrahydromethanopterin reductase YP_008735311.1 4354697 R 1246995 CDS YP_008735312.1 556566887 17444660 complement(4355493..4355978) 1 NC_022657.1 hypothetical protein 4355978 17444660 AFR_19935 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735312.1 4355493 R 1246995 CDS YP_008735313.1 556566888 17444661 4356127..4357089 1 NC_022657.1 COG4188 Predicted dienelactone hydrolase; hypothetical protein 4357089 17444661 AFR_19940 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735313.1 4356127 D 1246995 CDS YP_008735314.1 556566889 17444662 4357127..4359271 1 NC_022657.1 COG0744 Membrane carboxypeptidase (penicillin-binding protein); putative glycosyltransferase 4359271 17444662 AFR_19945 Actinoplanes friuliensis DSM 7358 putative glycosyltransferase YP_008735314.1 4357127 D 1246995 CDS YP_008735315.1 556566890 17444663 complement(4359275..4359958) 1 NC_022657.1 COG4565 Response regulator of citrate/malate metabolism; putative two-component system response regulator 4359958 17444663 AFR_19950 Actinoplanes friuliensis DSM 7358 putative two-component system response regulator YP_008735315.1 4359275 R 1246995 CDS YP_008735316.1 556566891 17444664 complement(4359955..4361526) 1 NC_022657.1 COG3290 Signal transduction histidine kinase regulating citrate/malate metabolism; putative two-component system sensor kinase 4361526 17444664 AFR_19955 Actinoplanes friuliensis DSM 7358 putative two-component system sensor kinase YP_008735316.1 4359955 R 1246995 CDS YP_008735317.1 556566892 17444665 4361576..4363003 1 NC_022657.1 COG1301 Na+/H+-dicarboxylate symporters; putative sodium:dicarboxylate symporter 4363003 17444665 AFR_19960 Actinoplanes friuliensis DSM 7358 putative sodium:dicarboxylate symporter YP_008735317.1 4361576 D 1246995 CDS YP_008735318.1 556566893 17444666 4363148..4364188 1 NC_022657.1 hypothetical protein 4364188 17444666 AFR_19965 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735318.1 4363148 D 1246995 CDS YP_008735319.1 556566894 17444667 complement(4364856..4365863) 1 NC_022657.1 COG1609 Transcriptional regulators; putative LacI-family transcriptional regulator 4365863 17444667 AFR_19970 Actinoplanes friuliensis DSM 7358 putative LacI-family transcriptional regulator YP_008735319.1 4364856 R 1246995 CDS YP_008735320.1 556566895 17444668 4365955..4368000 1 NC_022657.1 hypothetical protein 4368000 17444668 AFR_19975 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735320.1 4365955 D 1246995 CDS YP_008735321.1 556566896 17444669 4368102..4369895 1 NC_022657.1 hypothetical protein 4369895 17444669 AFR_19980 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735321.1 4368102 D 1246995 CDS YP_008735322.1 556566897 17444670 4370028..4370618 1 NC_022657.1 COG2177 Cell division protein; hypothetical protein 4370618 17444670 AFR_19985 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735322.1 4370028 D 1246995 CDS YP_008735323.1 556566898 17444671 4370615..4371172 1 NC_022657.1 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; putative RNA polymerase ECF-subfamily sigma factor 4371172 17444671 AFR_19990 Actinoplanes friuliensis DSM 7358 putative RNA polymerase ECF-subfamily sigma factor YP_008735323.1 4370615 D 1246995 CDS YP_008735324.1 556566899 17444672 complement(4371263..4372948) 1 NC_022657.1 cell surface-attached carbohydrate-binding protein 4372948 17444672 AFR_19995 Actinoplanes friuliensis DSM 7358 cell surface-attached carbohydrate-binding protein YP_008735324.1 4371263 R 1246995 CDS YP_008735325.1 556566900 17444673 4373135..4374592 1 NC_022657.1 COG0659 Sulfate permease and related transporters (MFS superfamily); putative sulfate transporter 4374592 17444673 AFR_20000 Actinoplanes friuliensis DSM 7358 putative sulfate transporter YP_008735325.1 4373135 D 1246995 CDS YP_008735326.1 556566901 17444674 4374602..4374985 1 NC_022657.1 COG0789 Predicted transcriptional regulators; MerR family transcriptional regulator 4374985 17444674 AFR_20005 Actinoplanes friuliensis DSM 7358 MerR family transcriptional regulator YP_008735326.1 4374602 D 1246995 CDS YP_008735327.1 556566902 17444675 complement(4375021..4376439) 1 NC_022657.1 COG0477 Permeases of the major facilitator superfamily; putative MFS transporter 4376439 17444675 AFR_20010 Actinoplanes friuliensis DSM 7358 putative MFS transporter YP_008735327.1 4375021 R 1246995 CDS YP_008735328.1 556566903 17444676 4376510..4377079 1 NC_022657.1 COG1309 Transcriptional regulator; HTH-type transcriptional regulator betI 4377079 17444676 AFR_20015 Actinoplanes friuliensis DSM 7358 HTH-type transcriptional regulator betI YP_008735328.1 4376510 D 1246995 CDS YP_008735329.1 556566904 17444677 4377116..4377640 1 NC_022657.1 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; putative RNA polymerase ECF-subfamily sigma factor 4377640 17444677 AFR_20020 Actinoplanes friuliensis DSM 7358 putative RNA polymerase ECF-subfamily sigma factor YP_008735329.1 4377116 D 1246995 CDS YP_008735330.1 556566905 17444678 4377637..4378311 1 NC_022657.1 hypothetical protein 4378311 17444678 AFR_20025 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735330.1 4377637 D 1246995 CDS YP_008735331.1 556566906 17444679 4378308..4379369 1 NC_022657.1 hypothetical protein 4379369 17444679 AFR_20030 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735331.1 4378308 D 1246995 CDS YP_008735332.1 556566907 17444680 4379448..4380179 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); keto acyl reductase 4380179 17444680 AFR_20035 Actinoplanes friuliensis DSM 7358 keto acyl reductase YP_008735332.1 4379448 D 1246995 CDS YP_008735333.1 556566908 17444681 complement(4380181..4381062) 1 NC_022657.1 COG0294 Dihydropteroate synthase and related enzymes; dihydropteroate synthase 4381062 17444681 AFR_20040 Actinoplanes friuliensis DSM 7358 dihydropteroate synthase YP_008735333.1 4380181 R 1246995 CDS YP_008735334.1 556566909 17444682 4381173..4382846 1 NC_022657.1 COG1132 ABC-type multidrug transport system, ATPase and permease components; hypothetical protein 4382846 17444682 AFR_20045 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735334.1 4381173 D 1246995 CDS YP_008735335.1 556566910 17444683 4382843..4384576 1 NC_022657.1 COG1132 ABC-type multidrug transport system, ATPase and permease components; ABC transporter-like protein 4384576 17444683 AFR_20050 Actinoplanes friuliensis DSM 7358 ABC transporter-like protein YP_008735335.1 4382843 D 1246995 CDS YP_008735336.1 556566911 17444684 complement(4384479..4385678) 1 NC_022657.1 COG0477 Permeases of the major facilitator superfamily; major facilitator superfamily protein 4385678 17444684 AFR_20055 Actinoplanes friuliensis DSM 7358 major facilitator superfamily protein YP_008735336.1 4384479 R 1246995 CDS YP_008735337.1 556566912 17444685 complement(4385737..4386975) 1 NC_022657.1 COG2041 Sulfite oxidase and related enzymes; oxidoreductase molybdopterin binding protein 4386975 17444685 AFR_20060 Actinoplanes friuliensis DSM 7358 oxidoreductase molybdopterin binding protein YP_008735337.1 4385737 R 1246995 CDS YP_008735338.1 556566913 17444686 4387161..4388027 1 NC_022657.1 hypothetical protein 4388027 17444686 AFR_20065 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735338.1 4387161 D 1246995 CDS YP_008735339.1 556566914 17444687 4388024..4388452 1 NC_022657.1 hypothetical protein 4388452 17444687 AFR_20070 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735339.1 4388024 D 1246995 CDS YP_008735340.1 556566915 17444688 4388428..4389066 1 NC_022657.1 hypothetical protein 4389066 17444688 AFR_20075 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735340.1 4388428 D 1246995 CDS YP_008735341.1 556566916 17444689 4389138..4390094 1 NC_022657.1 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases; f420-dependent oxidoreductase, g6pdh family protein 4390094 17444689 AFR_20080 Actinoplanes friuliensis DSM 7358 f420-dependent oxidoreductase, g6pdh family protein YP_008735341.1 4389138 D 1246995 CDS YP_008735342.1 556566917 17444690 4390131..4390991 1 NC_022657.1 ATP/GTP-binding protein 4390991 17444690 AFR_20085 Actinoplanes friuliensis DSM 7358 ATP/GTP-binding protein YP_008735342.1 4390131 D 1246995 CDS YP_008735343.1 556566918 17444691 4391029..4391442 1 NC_022657.1 COG4572 Putative cation transport regulator; hypothetical protein 4391442 17444691 AFR_20090 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735343.1 4391029 D 1246995 CDS YP_008735344.1 556566919 17444692 4391492..4392028 1 NC_022657.1 COG1396 Predicted transcriptional regulators; putative transcriptional regulator, XRE family protein 4392028 17444692 AFR_20095 Actinoplanes friuliensis DSM 7358 putative transcriptional regulator, XRE family protein YP_008735344.1 4391492 D 1246995 CDS YP_008735345.1 556566920 17444693 4392025..4392540 1 NC_022657.1 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; hypothetical protein 4392540 17444693 AFR_20100 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735345.1 4392025 D 1246995 CDS YP_008735346.1 556566921 17444694 4392605..4394845 1 NC_022657.1 COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain; PAS/PAC and GAF sensor-containing diguanylate cyclase/phosphodiesterase 4394845 17444694 AFR_20105 Actinoplanes friuliensis DSM 7358 PAS/PAC and GAF sensor-containing diguanylate cyclase/phosphodiesterase YP_008735346.1 4392605 D 1246995 CDS YP_008735347.1 556566922 17444695 4394850..4395482 1 NC_022657.1 COG1011 Predicted hydrolase (HAD superfamily); hydrolase (HAD superfamily)-like protein 4395482 17444695 AFR_20110 Actinoplanes friuliensis DSM 7358 hydrolase (HAD superfamily)-like protein YP_008735347.1 4394850 D 1246995 CDS YP_008735348.1 556566923 17444696 complement(4395436..4395972) 1 NC_022657.1 hypothetical protein 4395972 17444696 AFR_20115 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735348.1 4395436 R 1246995 CDS YP_008735349.1 556566924 17444697 4396125..4397231 1 NC_022657.1 COG1506 Dipeptidyl aminopeptidases/acylaminoacyl-peptidases; Lipase 6 4397231 17444697 AFR_20120 Actinoplanes friuliensis DSM 7358 Lipase 6 YP_008735349.1 4396125 D 1246995 CDS YP_008735350.1 556566925 17444698 complement(4397224..4397901) 1 NC_022657.1 hypothetical protein 4397901 17444698 AFR_20125 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735350.1 4397224 R 1246995 CDS YP_008735351.1 556566926 17444699 4397995..4399350 1 NC_022657.1 COG0515 Serine/threonine protein kinase; putative serine/threonine protein kinase 4399350 17444699 AFR_20130 Actinoplanes friuliensis DSM 7358 putative serine/threonine protein kinase YP_008735351.1 4397995 D 1246995 CDS YP_008735352.1 556566927 17444700 complement(4399354..4402725) 1 NC_022657.1 COG4988 ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components; Multidrug resistance protein 2 4402725 17444700 AFR_20135 Actinoplanes friuliensis DSM 7358 Multidrug resistance protein 2 YP_008735352.1 4399354 R 1246995 CDS YP_008735353.1 556566928 17444701 complement(4402722..4403702) 1 NC_022657.1 COG1294 Cytochrome bd-type quinol oxidase, subunit 2; cytochrome bd-I oxidase subunit II 4403702 17444701 AFR_20140 Actinoplanes friuliensis DSM 7358 cytochrome bd-I oxidase subunit II YP_008735353.1 4402722 R 1246995 CDS YP_008735354.1 556566929 17444702 complement(4403712..4405103) 1 NC_022657.1 COG1271 Cytochrome bd-type quinol oxidase, subunit 1; putative cytochrome oxidase subunit I 4405103 17444702 AFR_20145 Actinoplanes friuliensis DSM 7358 putative cytochrome oxidase subunit I YP_008735354.1 4403712 R 1246995 CDS YP_008735355.1 556566930 17444703 4405208..4405546 1 NC_022657.1 COG3682 Predicted transcriptional regulator; putative transcriptional regulator 4405546 17444703 AFR_20150 Actinoplanes friuliensis DSM 7358 putative transcriptional regulator YP_008735355.1 4405208 D 1246995 CDS YP_008735356.1 556566931 17444704 4405543..4406460 1 NC_022657.1 COG0501 Zn-dependent protease with chaperone function; hypothetical protein 4406460 17444704 AFR_20155 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735356.1 4405543 D 1246995 CDS YP_008735357.1 556566932 17444705 4406744..4407733 1 NC_022657.1 COG4942 Membrane-bound metallopeptidase; hypothetical protein 4407733 17444705 AFR_20160 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735357.1 4406744 D 1246995 CDS YP_008735358.1 556566933 17444706 4407805..4408707 1 NC_022657.1 COG3570 Streptomycin 6-kinase; aminoglycoside/hydroxyurea antibiotic resistance kinase 4408707 17444706 AFR_20165 Actinoplanes friuliensis DSM 7358 aminoglycoside/hydroxyurea antibiotic resistance kinase YP_008735358.1 4407805 D 1246995 CDS YP_008735359.1 556566934 17444707 complement(4408682..4409101) 1 NC_022657.1 COG1846 Transcriptional regulators; MarR family transcriptional regulator 4409101 17444707 AFR_20170 Actinoplanes friuliensis DSM 7358 MarR family transcriptional regulator YP_008735359.1 4408682 R 1246995 CDS YP_008735360.1 556566935 17444708 4409155..4410249 1 NC_022657.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); hydrolase 4410249 17444708 AFR_20175 Actinoplanes friuliensis DSM 7358 hydrolase YP_008735360.1 4409155 D 1246995 CDS YP_008735361.1 556566936 17444709 complement(4410213..4411655) 1 NC_022657.1 COG2199 FOG: GGDEF domain; PAS/PAC sensor-containing diguanylate cyclase/phosphodiesterase 4411655 17444709 AFR_20180 Actinoplanes friuliensis DSM 7358 PAS/PAC sensor-containing diguanylate cyclase/phosphodiesterase YP_008735361.1 4410213 R 1246995 CDS YP_008735362.1 556566937 17444710 4411763..4412539 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); short-chain dehydrogenase/reductase SDR 4412539 17444710 AFR_20185 Actinoplanes friuliensis DSM 7358 short-chain dehydrogenase/reductase SDR YP_008735362.1 4411763 D 1246995 CDS YP_008735363.1 556566938 17444711 complement(4412515..4412997) 1 NC_022657.1 COG5516 Conserved protein containing a Zn-ribbon-like motif, possibly RNA-binding; hypothetical protein 4412997 17444711 AFR_20190 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735363.1 4412515 R 1246995 CDS YP_008735364.1 556566939 17444712 4413081..4413941 1 NC_022657.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); alpha/beta hydrolase fold protein 4413941 17444712 AFR_20195 Actinoplanes friuliensis DSM 7358 alpha/beta hydrolase fold protein YP_008735364.1 4413081 D 1246995 CDS YP_008735365.1 556566940 17444713 4413974..4415167 1 NC_022657.1 COG0464 ATPases of the AAA+ class; ATPase 4415167 17444713 AFR_20200 Actinoplanes friuliensis DSM 7358 ATPase YP_008735365.1 4413974 D 1246995 CDS YP_008735366.1 556566941 17444714 4415164..4416339 1 NC_022657.1 hypothetical protein 4416339 17444714 AFR_20205 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735366.1 4415164 D 1246995 CDS YP_008735367.1 556566942 17444715 4416336..4417514 1 NC_022657.1 COG5438 Predicted multitransmembrane protein; yibe/f family protein 4417514 17444715 AFR_20210 Actinoplanes friuliensis DSM 7358 yibe/f family protein YP_008735367.1 4416336 D 1246995 CDS YP_008735368.1 556566943 17444716 complement(4417435..4418370) 1 NC_022657.1 COG1305 Transglutaminase-like enzymes, putative cysteine proteases; hypothetical protein 4418370 17444716 AFR_20215 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735368.1 4417435 R 1246995 CDS YP_008735369.1 556566944 17444717 complement(4418408..4418863) 1 NC_022657.1 COG1846 Transcriptional regulators; hypothetical protein 4418863 17444717 AFR_20220 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735369.1 4418408 R 1246995 CDS YP_008735370.1 556566945 17444718 complement(4418965..4419354) 1 NC_022657.1 hypothetical protein 4419354 17444718 AFR_20225 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735370.1 4418965 R 1246995 CDS YP_008735371.1 556566946 17444719 4419489..4419842 1 NC_022657.1 COG1263 Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific; methyltransferase 4419842 17444719 AFR_20230 Actinoplanes friuliensis DSM 7358 methyltransferase YP_008735371.1 4419489 D 1246995 CDS YP_008735372.1 556566947 17444720 complement(4419850..4420716) 1 NC_022657.1 COG0583 Transcriptional regulator; LysR family transcriptional regulator 4420716 17444720 AFR_20235 Actinoplanes friuliensis DSM 7358 LysR family transcriptional regulator YP_008735372.1 4419850 R 1246995 CDS YP_008735373.1 556566948 17444721 4420791..4421429 1 NC_022657.1 COG0693 Putative intracellular protease/amidase; ThiJ/PfpI domain-containing protein 4421429 17444721 AFR_20240 Actinoplanes friuliensis DSM 7358 ThiJ/PfpI domain-containing protein YP_008735373.1 4420791 D 1246995 CDS YP_008735374.1 556566949 17444722 complement(4421430..4422338) 1 NC_022657.1 hypothetical protein 4422338 17444722 AFR_20245 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735374.1 4421430 R 1246995 CDS YP_008735375.1 556566950 17444723 complement(4422420..4423025) 1 NC_022657.1 COG2188 Transcriptional regulators; Mannosyl-D-glycerate transport/metabolism system repressor mngR 4423025 17444723 AFR_20250 Actinoplanes friuliensis DSM 7358 Mannosyl-D-glycerate transport/metabolism system repressor mngR YP_008735375.1 4422420 R 1246995 CDS YP_008735376.1 556566951 17444724 complement(4423117..4423914) 1 NC_022657.1 COG0159 Tryptophan synthase alpha chain; tryptophan synthase 4423914 17444724 AFR_20255 Actinoplanes friuliensis DSM 7358 tryptophan synthase YP_008735376.1 4423117 R 1246995 CDS YP_008735377.1 556566952 17444725 complement(4423911..4425065) 1 NC_022657.1 COG0133 Tryptophan synthase beta chain; tryptophan synthase beta chain 4425065 17444725 AFR_20260 Actinoplanes friuliensis DSM 7358 tryptophan synthase beta chain YP_008735377.1 4423911 R 1246995 CDS YP_008735378.1 556566953 17444726 4425154..4425861 1 NC_022657.1 COG4424 Uncharacterized protein conserved in bacteria; hypothetical protein 4425861 17444726 AFR_20265 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735378.1 4425154 D 1246995 CDS YP_008735379.1 556566954 17444727 4425871..4426887 1 NC_022657.1 hypothetical protein 4426887 17444727 AFR_20270 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735379.1 4425871 D 1246995 CDS YP_008735380.1 556566955 17444728 complement(4426893..4427588) 1 NC_022657.1 COG0542 ATPases with chaperone activity, ATP-binding subunit; hypothetical protein 4427588 17444728 AFR_20275 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735380.1 4426893 R 1246995 CDS YP_008735381.1 556566956 17444729 complement(4427643..4428320) 1 NC_022657.1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; putative two-component system response regulator 4428320 17444729 AFR_20280 Actinoplanes friuliensis DSM 7358 putative two-component system response regulator YP_008735381.1 4427643 R 1246995 CDS YP_008735382.1 556566957 17444730 complement(4428308..4429480) 1 NC_022657.1 COG4585 Signal transduction histidine kinase; Sensor protein kinase walK 4429480 17444730 AFR_20285 Actinoplanes friuliensis DSM 7358 Sensor protein kinase walK YP_008735382.1 4428308 R 1246995 CDS YP_008735383.1 556566958 17444731 4429634..4431007 1 NC_022657.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); putative aminopeptidase ybaC 4431007 17444731 AFR_20290 Actinoplanes friuliensis DSM 7358 putative aminopeptidase ybaC YP_008735383.1 4429634 D 1246995 CDS YP_008735384.1 556566959 17444732 4431066..4431566 1 NC_022657.1 COG1733 Predicted transcriptional regulators; HxlR family transcriptional regulator 4431566 17444732 AFR_20295 Actinoplanes friuliensis DSM 7358 HxlR family transcriptional regulator YP_008735384.1 4431066 D 1246995 CDS YP_008735385.1 556566960 17444733 complement(4431570..4432424) 1 NC_022657.1 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component; hypothetical protein 4432424 17444733 AFR_20300 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735385.1 4431570 R 1246995 CDS YP_008735386.1 556566961 17444734 complement(4432417..4433349) 1 NC_022657.1 COG1131 ABC-type multidrug transport system, ATPase component; ABC transporter 4433349 17444734 AFR_20305 Actinoplanes friuliensis DSM 7358 ABC transporter YP_008735386.1 4432417 R 1246995 CDS YP_008735387.1 556566962 17444735 complement(4433346..4434434) 1 NC_022657.1 COG2884 Predicted ATPase involved in cell division; hypothetical protein 4434434 17444735 AFR_20310 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735387.1 4433346 R 1246995 CDS YP_008735388.1 556566963 17444736 4434597..4435265 1 NC_022657.1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; putative two-component system response regulator 4435265 17444736 AFR_20315 Actinoplanes friuliensis DSM 7358 putative two-component system response regulator YP_008735388.1 4434597 D 1246995 CDS YP_008735389.1 556566964 17444737 4435268..4436629 1 NC_022657.1 COG0642 Signal transduction histidine kinase; putative two-component system sensor kinase 4436629 17444737 AFR_20320 Actinoplanes friuliensis DSM 7358 putative two-component system sensor kinase YP_008735389.1 4435268 D 1246995 CDS YP_008735390.1 556566965 17444738 complement(4436612..4437349) 1 NC_022657.1 hypothetical protein 4437349 17444738 AFR_20325 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735390.1 4436612 R 1246995 CDS YP_008735391.1 556566966 17444739 4437487..4438236 1 NC_022657.1 COG1376 Uncharacterized protein conserved in bacteria; hypothetical protein 4438236 17444739 AFR_20330 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735391.1 4437487 D 1246995 CDS YP_008735392.1 556566967 17444740 4438278..4439051 1 NC_022657.1 COG0500 SAM-dependent methyltransferases; type 11 methyltransferase 4439051 17444740 AFR_20335 Actinoplanes friuliensis DSM 7358 type 11 methyltransferase YP_008735392.1 4438278 D 1246995 CDS YP_008735393.1 556566968 17444741 4439139..4439867 1 NC_022657.1 COG4549 Uncharacterized protein conserved in bacteria; hypothetical protein 4439867 17444741 AFR_20340 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735393.1 4439139 D 1246995 CDS YP_008735394.1 556566969 17444742 4439923..4440426 1 NC_022657.1 hemerythrin-like protein 4440426 17444742 AFR_20345 Actinoplanes friuliensis DSM 7358 hemerythrin-like protein YP_008735394.1 4439923 D 1246995 CDS YP_008735395.1 556566970 17444743 complement(4440427..4441062) 1 NC_022657.1 COG3832 Uncharacterized conserved protein; hypothetical protein 4441062 17444743 AFR_20350 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735395.1 4440427 R 1246995 CDS YP_008735396.1 556566971 17444744 complement(4441055..4441429) 1 NC_022657.1 COG0640 Predicted transcriptional regulators; Arsenical resistance operon repressor 4441429 17444744 AFR_20355 Actinoplanes friuliensis DSM 7358 Arsenical resistance operon repressor YP_008735396.1 4441055 R 1246995 CDS YP_008735397.1 556566972 17444745 4441727..4442224 1 NC_022657.1 hypothetical protein 4442224 17444745 AFR_20360 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735397.1 4441727 D 1246995 CDS YP_008735398.1 556566973 17444746 complement(4442221..4442490) 1 NC_022657.1 COG5552 Uncharacterized conserved protein; hypothetical protein 4442490 17444746 AFR_20365 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735398.1 4442221 R 1246995 CDS YP_008735399.1 556566974 17444747 complement(4442500..4443000) 1 NC_022657.1 hypothetical protein 4443000 17444747 AFR_20370 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735399.1 4442500 R 1246995 CDS YP_008735400.1 556566975 17444748 complement(4443093..4443743) 1 NC_022657.1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; response regulator receiver 4443743 17444748 AFR_20375 Actinoplanes friuliensis DSM 7358 response regulator receiver YP_008735400.1 4443093 R 1246995 CDS YP_008735401.1 556566976 17444749 complement(4443740..4444867) 1 NC_022657.1 COG4585 Signal transduction histidine kinase; integral membrane sensor signal transduction histidine kinase 4444867 17444749 AFR_20380 Actinoplanes friuliensis DSM 7358 integral membrane sensor signal transduction histidine kinase YP_008735401.1 4443740 R 1246995 CDS YP_008735402.1 556566977 17444750 4444959..4446581 1 NC_022657.1 hypothetical protein 4446581 17444750 AFR_20385 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735402.1 4444959 D 1246995 CDS YP_008735403.1 556566978 17444751 4446732..4447841 1 NC_022657.1 hypothetical protein 4447841 17444751 AFR_20390 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735403.1 4446732 D 1246995 CDS YP_008735404.1 556566979 17444752 complement(4447849..4448856) 1 NC_022657.1 COG2070 Dioxygenases related to 2-nitropropane dioxygenase; putative dioxygenase 4448856 17444752 AFR_20395 Actinoplanes friuliensis DSM 7358 putative dioxygenase YP_008735404.1 4447849 R 1246995 CDS YP_008735405.1 556566980 17444753 complement(4448872..4450029) 1 NC_022657.1 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component; Leu/Ile/Val-binding protein 4450029 17444753 AFR_20400 Actinoplanes friuliensis DSM 7358 Leu/Ile/Val-binding protein YP_008735405.1 4448872 R 1246995 CDS YP_008735406.1 556566981 17444754 4450128..4452086 1 NC_022657.1 COG2199 FOG: GGDEF domain; Signaling protein ykoW 4452086 17444754 AFR_20405 Actinoplanes friuliensis DSM 7358 Signaling protein ykoW YP_008735406.1 4450128 D 1246995 CDS YP_008735407.1 556566982 17444755 complement(4452154..4454253) 1 NC_022657.1 COG0753 Catalase; catalase 4454253 17444755 AFR_20410 Actinoplanes friuliensis DSM 7358 catalase YP_008735407.1 4452154 R 1246995 CDS YP_008735408.1 556566983 17444756 complement(4454331..4455146) 1 NC_022657.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); putative alpha/beta hydrolase fold protein 4455146 17444756 AFR_20415 Actinoplanes friuliensis DSM 7358 putative alpha/beta hydrolase fold protein YP_008735408.1 4454331 R 1246995 CDS YP_008735409.1 556566984 17444757 complement(4455156..4456346) 1 NC_022657.1 hypothetical protein 4456346 17444757 AFR_20420 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735409.1 4455156 R 1246995 CDS YP_008735410.1 556566985 17444758 4456588..4457574 1 NC_022657.1 COG1135 ABC-type metal ion transport system, ATPase component; putative ABC transporter ATP-binding protein 4457574 17444758 AFR_20425 Actinoplanes friuliensis DSM 7358 putative ABC transporter ATP-binding protein YP_008735410.1 4456588 D 1246995 CDS YP_008735411.1 556566986 17444759 4457628..4458227 1 NC_022657.1 COG2011 ABC-type metal ion transport system, permease component; ABC transporter permease 4458227 17444759 AFR_20430 Actinoplanes friuliensis DSM 7358 ABC transporter permease YP_008735411.1 4457628 D 1246995 CDS YP_008735412.1 556566987 17444760 4458243..4459061 1 NC_022657.1 COG1464 ABC-type metal ion transport system, periplasmic component/surface antigen; putative ABC transporter substrate-binding protein 4459061 17444760 AFR_20435 Actinoplanes friuliensis DSM 7358 putative ABC transporter substrate-binding protein YP_008735412.1 4458243 D 1246995 CDS YP_008735413.1 556566988 17444761 complement(4459167..4459631) 1 NC_022657.1 COG1846 Transcriptional regulators; MarR family transcriptional regulator 4459631 17444761 AFR_20440 Actinoplanes friuliensis DSM 7358 MarR family transcriptional regulator YP_008735413.1 4459167 R 1246995 CDS YP_008735414.1 556566989 17444762 4459724..4460098 1 NC_022657.1 COG0569 K+ transport systems, NAD-binding component; DoxX family protein 4460098 17444762 AFR_20445 Actinoplanes friuliensis DSM 7358 DoxX family protein YP_008735414.1 4459724 D 1246995 CDS YP_008735415.1 556566990 17444763 4460180..4461805 1 NC_022657.1 COG0166 Glucose-6-phosphate isomerase; glucose-6-phosphate isomerase 4461805 pgi 17444763 pgi Actinoplanes friuliensis DSM 7358 glucose-6-phosphate isomerase YP_008735415.1 4460180 D 1246995 CDS YP_008735416.1 556566991 17444764 4461861..4462943 1 NC_022657.1 hypothetical protein 4462943 17444764 AFR_20455 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735416.1 4461861 D 1246995 CDS YP_008735417.1 556566992 17444765 4463157..4464461 1 NC_022657.1 COG3979 Uncharacterized protein contain chitin-binding domain type 3; chitinase 4464461 17444765 AFR_20460 Actinoplanes friuliensis DSM 7358 chitinase YP_008735417.1 4463157 D 1246995 CDS YP_008735418.1 556566993 17444766 4464579..4465175 1 NC_022657.1 COG1280 Putative threonine efflux protein; lysine exporter LysE/YggA 4465175 17444766 AFR_20465 Actinoplanes friuliensis DSM 7358 lysine exporter LysE/YggA YP_008735418.1 4464579 D 1246995 CDS YP_008735419.1 556566994 17444767 4465307..4466410 1 NC_022657.1 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases; putative luciferase-like monooxygenase 4466410 17444767 AFR_20470 Actinoplanes friuliensis DSM 7358 putative luciferase-like monooxygenase YP_008735419.1 4465307 D 1246995 CDS YP_008735420.1 556566995 17444768 4466407..4467021 1 NC_022657.1 COG0431 Predicted flavoprotein; FMN reductase 4467021 17444768 AFR_20475 Actinoplanes friuliensis DSM 7358 FMN reductase YP_008735420.1 4466407 D 1246995 CDS YP_008735421.1 556566996 17444769 4467158..4467721 1 NC_022657.1 COG0406 Fructose-2,6-bisphosphatase; putative phosphoglycerate mutase 4467721 17444769 AFR_20480 Actinoplanes friuliensis DSM 7358 putative phosphoglycerate mutase YP_008735421.1 4467158 D 1246995 CDS YP_008735422.1 556566997 17444770 complement(4467903..4468487) 1 NC_022657.1 COG1309 Transcriptional regulator; regulatory protein TetR 4468487 17444770 AFR_20485 Actinoplanes friuliensis DSM 7358 regulatory protein TetR YP_008735422.1 4467903 R 1246995 CDS YP_008735423.1 556566998 17444771 4468555..4469331 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); short chain dehydrogenase 4469331 17444771 AFR_20490 Actinoplanes friuliensis DSM 7358 short chain dehydrogenase YP_008735423.1 4468555 D 1246995 CDS YP_008735424.1 556566999 17444772 4469333..4469698 1 NC_022657.1 hypothetical protein 4469698 17444772 AFR_20495 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735424.1 4469333 D 1246995 CDS YP_008735425.1 556567000 17444773 complement(4469774..4470868) 1 NC_022657.1 COG1940 Transcriptional regulator/sugar kinase; ROK family protein 4470868 17444773 AFR_20500 Actinoplanes friuliensis DSM 7358 ROK family protein YP_008735425.1 4469774 R 1246995 CDS YP_008735426.1 556567001 17444774 4470912..4472126 1 NC_022657.1 COG2814 Arabinose efflux permease; putative MFS transporter 4472126 17444774 AFR_20505 Actinoplanes friuliensis DSM 7358 putative MFS transporter YP_008735426.1 4470912 D 1246995 CDS YP_008735427.1 556567002 17444775 complement(4472112..4473320) 1 NC_022657.1 COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily; bifunctional D-altronate/D-mannonate dehydratase 4473320 17444775 AFR_20510 Actinoplanes friuliensis DSM 7358 bifunctional D-altronate/D-mannonate dehydratase YP_008735427.1 4472112 R 1246995 CDS YP_008735428.1 556567003 17444776 complement(4473322..4474161) 1 NC_022657.1 COG1177 ABC-type spermidine/putrescine transport system, permease component II; ABC transporter permease 4474161 17444776 AFR_20515 Actinoplanes friuliensis DSM 7358 ABC transporter permease YP_008735428.1 4473322 R 1246995 CDS YP_008735429.1 556567004 17444777 complement(4474161..4475036) 1 NC_022657.1 COG1176 ABC-type spermidine/putrescine transport system, permease component I; ABC transporter permease 4475036 17444777 AFR_20520 Actinoplanes friuliensis DSM 7358 ABC transporter permease YP_008735429.1 4474161 R 1246995 CDS YP_008735430.1 556567005 17444778 complement(4475036..4476097) 1 NC_022657.1 COG3842 ABC-type spermidine/putrescine transport systems, ATPase components; ABC-type spermidine/putrescine transport system, ATPase component 4476097 17444778 AFR_20525 Actinoplanes friuliensis DSM 7358 ABC-type spermidine/putrescine transport system, ATPase component YP_008735430.1 4475036 R 1246995 CDS YP_008735431.1 556567006 17444779 complement(4476094..4477311) 1 NC_022657.1 COG4134 ABC-type uncharacterized transport system, periplasmic component; putative ABC transporter substrate-binding protein 4477311 17444779 AFR_20530 Actinoplanes friuliensis DSM 7358 putative ABC transporter substrate-binding protein YP_008735431.1 4476094 R 1246995 CDS YP_008735432.1 556567007 17444780 complement(4477339..4478328) 1 NC_022657.1 COG1609 Transcriptional regulators; putative LacI-family transcriptional regulator 4478328 17444780 AFR_20535 Actinoplanes friuliensis DSM 7358 putative LacI-family transcriptional regulator YP_008735432.1 4477339 R 1246995 CDS YP_008735433.1 556567008 17444781 4478549..4479493 1 NC_022657.1 COG1609 Transcriptional regulators; putative LacI family transcriptional regulator 4479493 17444781 AFR_20540 Actinoplanes friuliensis DSM 7358 putative LacI family transcriptional regulator YP_008735433.1 4478549 D 1246995 CDS YP_008735434.1 556567009 17444782 4479490..4480599 1 NC_022657.1 hypothetical protein 4480599 17444782 AFR_20545 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735434.1 4479490 D 1246995 CDS YP_008735435.1 556567010 17444783 4480685..4481146 1 NC_022657.1 hypothetical protein 4481146 17444783 AFR_20550 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735435.1 4480685 D 1246995 CDS YP_008735436.1 556567011 17444784 complement(4481148..4481693) 1 NC_022657.1 hypothetical protein 4481693 17444784 AFR_20555 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735436.1 4481148 R 1246995 CDS YP_008735437.1 556567012 17444785 4481892..4483040 1 NC_022657.1 COG0845 Membrane-fusion protein; putative macrolide-specific efflux protein macA 4483040 17444785 AFR_20560 Actinoplanes friuliensis DSM 7358 putative macrolide-specific efflux protein macA YP_008735437.1 4481892 D 1246995 CDS YP_008735438.1 556567013 17444786 4483107..4483862 1 NC_022657.1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; putative two-component system response regulator 4483862 17444786 AFR_20565 Actinoplanes friuliensis DSM 7358 putative two-component system response regulator YP_008735438.1 4483107 D 1246995 CDS YP_008735439.1 556567014 17444787 4483859..4485370 1 NC_022657.1 COG0642 Signal transduction histidine kinase; putative two-component system sensor kinase 4485370 17444787 AFR_20570 Actinoplanes friuliensis DSM 7358 putative two-component system sensor kinase YP_008735439.1 4483859 D 1246995 CDS YP_008735440.1 556567015 17444788 4485436..4486608 1 NC_022657.1 COG0845 Membrane-fusion protein; hypothetical protein 4486608 17444788 AFR_20575 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735440.1 4485436 D 1246995 CDS YP_008735441.1 556567016 17444789 4486605..4487339 1 NC_022657.1 COG1136 ABC-type antimicrobial peptide transport system, ATPase component; putative ABC transporter ATP-binding protein 4487339 17444789 AFR_20580 Actinoplanes friuliensis DSM 7358 putative ABC transporter ATP-binding protein YP_008735441.1 4486605 D 1246995 CDS YP_008735442.1 556567017 17444790 4487336..4488535 1 NC_022657.1 COG0577 ABC-type antimicrobial peptide transport system, permease component; Macrolide export ATP-binding/permease protein macB 4488535 17444790 AFR_20585 Actinoplanes friuliensis DSM 7358 Macrolide export ATP-binding/permease protein macB YP_008735442.1 4487336 D 1246995 CDS YP_008735443.1 556567018 17444791 4488544..4489062 1 NC_022657.1 hypothetical protein 4489062 17444791 AFR_20590 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735443.1 4488544 D 1246995 CDS YP_008735444.1 556567019 17444792 complement(4489059..4489838) 1 NC_022657.1 hypothetical protein 4489838 17444792 AFR_20595 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735444.1 4489059 R 1246995 CDS YP_008735445.1 556567020 17444793 4490002..4492767 1 NC_022657.1 COG2771 DNA-binding HTH domain-containing proteins; HTH-type transcriptional regulator malT 4492767 17444793 AFR_20600 Actinoplanes friuliensis DSM 7358 HTH-type transcriptional regulator malT YP_008735445.1 4490002 D 1246995 CDS YP_008735446.1 556567021 17444794 4492857..4495085 1 NC_022657.1 COG3227 Zinc metalloprotease (elastase); zinc metalloprotease 4495085 17444794 AFR_20605 Actinoplanes friuliensis DSM 7358 zinc metalloprotease YP_008735446.1 4492857 D 1246995 CDS YP_008735447.1 556567022 17444795 4495342..4495587 1 NC_022657.1 hypothetical protein 4495587 17444795 AFR_20610 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735447.1 4495342 D 1246995 CDS YP_008735448.1 556567023 17444796 complement(4495645..4495950) 1 NC_022657.1 GCN5-related N-acetyltransferase 4495950 17444796 AFR_20615 Actinoplanes friuliensis DSM 7358 GCN5-related N-acetyltransferase YP_008735448.1 4495645 R 1246995 CDS YP_008735449.1 556567024 17444797 complement(4495963..4496658) 1 NC_022657.1 COG2154 Pterin-4a-carbinolamine dehydratase; pterin-4-alpha-carbinolamine dehydratase 4496658 17444797 AFR_20620 Actinoplanes friuliensis DSM 7358 pterin-4-alpha-carbinolamine dehydratase YP_008735449.1 4495963 R 1246995 CDS YP_008735450.1 556567025 17444798 complement(4496785..4497780) 1 NC_022657.1 COG0861 Membrane protein TerC, possibly involved in tellurium resistance; integral membrane protein TerC 4497780 17444798 AFR_20625 Actinoplanes friuliensis DSM 7358 integral membrane protein TerC YP_008735450.1 4496785 R 1246995 CDS YP_008735451.1 556567026 17444799 complement(4497898..4498668) 1 NC_022657.1 COG3384 Uncharacterized conserved protein; 4,5-DOPA dioxygenase extradiol 4498668 17444799 AFR_20630 Actinoplanes friuliensis DSM 7358 4,5-DOPA dioxygenase extradiol YP_008735451.1 4497898 R 1246995 CDS YP_008735452.1 556567027 17444800 complement(4498731..4499942) 1 NC_022657.1 COG4102 Uncharacterized protein conserved in bacteria; hypothetical protein 4499942 17444800 AFR_20635 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735452.1 4498731 R 1246995 CDS YP_008735453.1 556567028 17444801 complement(4499957..4501210) 1 NC_022657.1 COG5267 Uncharacterized protein conserved in bacteria; hypothetical protein 4501210 17444801 AFR_20640 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735453.1 4499957 R 1246995 CDS YP_008735454.1 556567029 17444802 4501537..4502184 1 NC_022657.1 hypothetical protein 4502184 17444802 AFR_20645 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735454.1 4501537 D 1246995 CDS YP_008735455.1 556567030 17444803 4502207..4503700 1 NC_022657.1 COG0531 Amino acid transporters; putative amino acid permease 4503700 17444803 AFR_20650 Actinoplanes friuliensis DSM 7358 putative amino acid permease YP_008735455.1 4502207 D 1246995 CDS YP_008735456.1 556567031 17444804 4503697..4504287 1 NC_022657.1 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; putative GCN5-related N-acetyltransferase 4504287 17444804 AFR_20655 Actinoplanes friuliensis DSM 7358 putative GCN5-related N-acetyltransferase YP_008735456.1 4503697 D 1246995 CDS YP_008735457.1 556567032 17444805 4504348..4505019 1 NC_022657.1 COG0500 SAM-dependent methyltransferases; methyltransferase type 11 4505019 17444805 AFR_20660 Actinoplanes friuliensis DSM 7358 methyltransferase type 11 YP_008735457.1 4504348 D 1246995 CDS YP_008735458.1 556567033 17444806 complement(4505204..4505347) 1 NC_022657.1 hypothetical protein 4505347 17444806 AFR_20665 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735458.1 4505204 R 1246995 CDS YP_008735459.1 556567034 17444807 complement(4505810..4506505) 1 NC_022657.1 COG1309 Transcriptional regulator; transcriptional regulator 4506505 17444807 AFR_20670 Actinoplanes friuliensis DSM 7358 transcriptional regulator YP_008735459.1 4505810 R 1246995 CDS YP_008735460.1 556567035 17444808 4506639..4506878 1 NC_022657.1 hypothetical protein 4506878 17444808 AFR_20675 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735460.1 4506639 D 1246995 CDS YP_008735461.1 556567036 17444809 complement(4507051..4507812) 1 NC_022657.1 COG2188 Transcriptional regulators; GntR family transcriptional regulator 4507812 17444809 AFR_20680 Actinoplanes friuliensis DSM 7358 GntR family transcriptional regulator YP_008735461.1 4507051 R 1246995 CDS YP_008735462.1 556567037 17444810 4507986..4508939 1 NC_022657.1 COG0524 Sugar kinases, ribokinase family; IolC protein 4508939 17444810 AFR_20685 Actinoplanes friuliensis DSM 7358 IolC protein YP_008735462.1 4507986 D 1246995 CDS YP_008735463.1 556567038 17444811 4508932..4509801 1 NC_022657.1 hypothetical protein 4509801 17444811 AFR_20690 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735463.1 4508932 D 1246995 CDS YP_008735464.1 556567039 17444812 4509798..4510673 1 NC_022657.1 COG3718 Uncharacterized enzyme involved in inositol metabolism; putative myo-inositol catabolism protein IolB 4510673 17444812 AFR_20695 Actinoplanes friuliensis DSM 7358 putative myo-inositol catabolism protein IolB YP_008735464.1 4509798 D 1246995 CDS YP_008735465.1 556567040 17444813 4510670..4512523 1 NC_022657.1 COG3962 Acetolactate synthase; putative myo-inositol catabolism protein IolD 4512523 17444813 AFR_20700 Actinoplanes friuliensis DSM 7358 putative myo-inositol catabolism protein IolD YP_008735465.1 4510670 D 1246995 CDS YP_008735466.1 556567041 17444814 4512539..4514035 1 NC_022657.1 COG1012 NAD-dependent aldehyde dehydrogenases; methylmalonate-semialdehyde dehydrogenase 4514035 17444814 AFR_20705 Actinoplanes friuliensis DSM 7358 methylmalonate-semialdehyde dehydrogenase YP_008735466.1 4512539 D 1246995 CDS YP_008735467.1 556567042 17444815 4514045..4514944 1 NC_022657.1 COG1082 Sugar phosphate isomerases/epimerases; inosose dehydratase 4514944 17444815 AFR_20710 Actinoplanes friuliensis DSM 7358 inosose dehydratase YP_008735467.1 4514045 D 1246995 CDS YP_008735468.1 556567043 17444816 4514968..4515963 1 NC_022657.1 COG1879 ABC-type sugar transport system, periplasmic component; simple sugar transport system substrate-binding protein 4515963 17444816 AFR_20715 Actinoplanes friuliensis DSM 7358 simple sugar transport system substrate-binding protein YP_008735468.1 4514968 D 1246995 CDS YP_008735469.1 556567044 17444817 4516073..4517104 1 NC_022657.1 COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components; sugar ABC transporter permease 4517104 17444817 AFR_20720 Actinoplanes friuliensis DSM 7358 sugar ABC transporter permease YP_008735469.1 4516073 D 1246995 CDS YP_008735470.1 556567045 17444818 4517107..4517922 1 NC_022657.1 COG1129 ABC-type sugar transport system, ATPase component; ABC transporter 4517922 17444818 AFR_20725 Actinoplanes friuliensis DSM 7358 ABC transporter YP_008735470.1 4517107 D 1246995 CDS YP_008735471.1 556567046 17444819 4517954..4518970 1 NC_022657.1 COG0673 Predicted dehydrogenases and related proteins; oxidoreductase domain-containing protein 4518970 17444819 AFR_20730 Actinoplanes friuliensis DSM 7358 oxidoreductase domain-containing protein YP_008735471.1 4517954 D 1246995 CDS YP_008735472.1 556567047 17444820 4518967..4519827 1 NC_022657.1 COG1082 Sugar phosphate isomerases/epimerases; xylose isomerase domain-containing protein 4519827 17444820 AFR_20735 Actinoplanes friuliensis DSM 7358 xylose isomerase domain-containing protein YP_008735472.1 4518967 D 1246995 CDS YP_008735473.1 556567048 17444821 complement(4519796..4520569) 1 NC_022657.1 COG3622 Hydroxypyruvate isomerase; hydroxypyruvate isomerase 4520569 17444821 AFR_20740 Actinoplanes friuliensis DSM 7358 hydroxypyruvate isomerase YP_008735473.1 4519796 R 1246995 CDS YP_008735474.1 556567049 17444822 complement(4520578..4521561) 1 NC_022657.1 COG0673 Predicted dehydrogenases and related proteins; oxidoreductase domain-containing protein 4521561 17444822 AFR_20745 Actinoplanes friuliensis DSM 7358 oxidoreductase domain-containing protein YP_008735474.1 4520578 R 1246995 CDS YP_008735475.1 556567050 17444823 4521658..4522647 1 NC_022657.1 COG1609 Transcriptional regulators; LacI family transcriptional regulator 4522647 17444823 AFR_20750 Actinoplanes friuliensis DSM 7358 LacI family transcriptional regulator YP_008735475.1 4521658 D 1246995 CDS YP_008735476.1 556567051 17444824 complement(4523197..4524540) 1 NC_022657.1 COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)proteins; OmpA/MotB domain-containing protein 4524540 17444824 AFR_20755 Actinoplanes friuliensis DSM 7358 OmpA/MotB domain-containing protein YP_008735476.1 4523197 R 1246995 CDS YP_008735477.1 556567052 17444825 complement(4525196..4526200) 1 NC_022657.1 COG1082 Sugar phosphate isomerases/epimerases; xylose isomerase domain-containing protein 4526200 17444825 AFR_20760 Actinoplanes friuliensis DSM 7358 xylose isomerase domain-containing protein YP_008735477.1 4525196 R 1246995 CDS YP_008735478.1 556567053 17444826 complement(4526220..4527386) 1 NC_022657.1 COG0673 Predicted dehydrogenases and related proteins; putative oxidoreductase 4527386 17444826 AFR_20765 Actinoplanes friuliensis DSM 7358 putative oxidoreductase YP_008735478.1 4526220 R 1246995 CDS YP_008735479.1 556567054 17444827 4527532..4528527 1 NC_022657.1 COG1609 Transcriptional regulators; LacI family transcriptional regulator 4528527 17444827 AFR_20770 Actinoplanes friuliensis DSM 7358 LacI family transcriptional regulator YP_008735479.1 4527532 D 1246995 CDS YP_008735480.1 556567055 17444828 complement(4528524..4529831) 1 NC_022657.1 COG1541 Coenzyme F390 synthetase; phenylacetate-CoA ligase 4529831 17444828 AFR_20775 Actinoplanes friuliensis DSM 7358 phenylacetate-CoA ligase YP_008735480.1 4528524 R 1246995 CDS YP_008735481.1 556567056 17444829 complement(4529850..4530497) 1 NC_022657.1 COG1309 Transcriptional regulator; TetR family transcriptional regulator 4530497 17444829 AFR_20780 Actinoplanes friuliensis DSM 7358 TetR family transcriptional regulator YP_008735481.1 4529850 R 1246995 CDS YP_008735482.1 556567057 17444830 complement(4530494..4530796) 1 NC_022657.1 COG2050 Uncharacterized protein, possibly involved in aromatic compounds catabolism; phenylacetic acid degradation protein PaaD 4530796 17444830 AFR_20785 Actinoplanes friuliensis DSM 7358 phenylacetic acid degradation protein PaaD YP_008735482.1 4530494 R 1246995 CDS YP_008735483.1 556567058 17444831 4530993..4532681 1 NC_022657.1 COG1012 NAD-dependent aldehyde dehydrogenases; Retinal dehydrogenase 1 4532681 17444831 AFR_20790 Actinoplanes friuliensis DSM 7358 Retinal dehydrogenase 1 YP_008735483.1 4530993 D 1246995 CDS YP_008735484.1 556567059 17444832 4532674..4533888 1 NC_022657.1 COG0183 Acetyl-CoA acetyltransferase; beta-ketoadipyl CoA thiolase 4533888 17444832 AFR_20795 Actinoplanes friuliensis DSM 7358 beta-ketoadipyl CoA thiolase YP_008735484.1 4532674 D 1246995 CDS YP_008735485.1 556567060 17444833 4533888..4534628 1 NC_022657.1 COG1024 Enoyl-CoA hydratase/carnithine racemase; 3-hydroxybutyryl-CoA dehydratase 4534628 17444833 AFR_20800 Actinoplanes friuliensis DSM 7358 3-hydroxybutyryl-CoA dehydratase YP_008735485.1 4533888 D 1246995 CDS YP_008735486.1 556567061 17444834 4534625..4535482 1 NC_022657.1 COG1250 3-hydroxyacyl-CoA dehydrogenase; 3-hydroxybutyryl-CoA dehydrogenase PaaC 4535482 17444834 AFR_20805 Actinoplanes friuliensis DSM 7358 3-hydroxybutyryl-CoA dehydrogenase PaaC YP_008735486.1 4534625 D 1246995 CDS YP_008735487.1 556567062 17444835 4535479..4536420 1 NC_022657.1 COG3396 Uncharacterized conserved protein; phenylacetate-CoA oxygenase subunit PaaA 4536420 paaA 17444835 paaA Actinoplanes friuliensis DSM 7358 phenylacetate-CoA oxygenase subunit PaaA YP_008735487.1 4535479 D 1246995 CDS YP_008735488.1 556567063 17444836 4536417..4536713 1 NC_022657.1 COG3460 Uncharacterized enzyme of phenylacetate metabolism; phenylacetate-CoA oxygenase subunit PaaB 4536713 paaB 17444836 paaB Actinoplanes friuliensis DSM 7358 phenylacetate-CoA oxygenase subunit PaaB YP_008735488.1 4536417 D 1246995 CDS YP_008735489.1 556567064 17444837 4536724..4537599 1 NC_022657.1 COG3396 Uncharacterized conserved protein; Phenylacetic acid degradation protein paaC 4537599 17444837 AFR_20820 Actinoplanes friuliensis DSM 7358 Phenylacetic acid degradation protein paaC YP_008735489.1 4536724 D 1246995 CDS YP_008735490.1 556567065 17444838 4537593..4538084 1 NC_022657.1 COG2151 Predicted metal-sulfur cluster biosynthetic enzyme; Phenylacetic acid degradation protein paaD 4538084 17444838 AFR_20825 Actinoplanes friuliensis DSM 7358 Phenylacetic acid degradation protein paaD YP_008735490.1 4537593 D 1246995 CDS YP_008735491.1 556567066 17444839 4538086..4539144 1 NC_022657.1 COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1; phenylacetic acid degradation NADH oxidoreductase 4539144 17444839 AFR_20830 Actinoplanes friuliensis DSM 7358 phenylacetic acid degradation NADH oxidoreductase YP_008735491.1 4538086 D 1246995 CDS YP_008735492.1 556567067 17444840 complement(4539779..4540429) 1 NC_022657.1 hypothetical protein 4540429 17444840 AFR_20835 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735492.1 4539779 R 1246995 CDS YP_008735493.1 556567068 17444841 complement(4540616..4541593) 1 NC_022657.1 ArsR family transcriptional regulator 4541593 17444841 AFR_20840 Actinoplanes friuliensis DSM 7358 ArsR family transcriptional regulator YP_008735493.1 4540616 R 1246995 CDS YP_008735494.1 556567069 17444842 4541658..4542638 1 NC_022657.1 COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases); aldo/keto reductase 4542638 17444842 AFR_20845 Actinoplanes friuliensis DSM 7358 aldo/keto reductase YP_008735494.1 4541658 D 1246995 CDS YP_008735495.1 556567070 17444843 4542703..4544913 1 NC_022657.1 COG2199 FOG: GGDEF domain; diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s) 4544913 17444843 AFR_20850 Actinoplanes friuliensis DSM 7358 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s) YP_008735495.1 4542703 D 1246995 CDS YP_008735496.1 556567071 17444844 complement(4544915..4545517) 1 NC_022657.1 COG0500 SAM-dependent methyltransferases; ubiquinone/menaquinone biosynthesis methyltransferase ubiE 4545517 17444844 AFR_20855 Actinoplanes friuliensis DSM 7358 ubiquinone/menaquinone biosynthesis methyltransferase ubiE YP_008735496.1 4544915 R 1246995 CDS YP_008735497.1 556567072 17444845 4545571..4546074 1 NC_022657.1 hypothetical protein 4546074 17444845 AFR_20860 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735497.1 4545571 D 1246995 CDS YP_008735498.1 556567073 17444846 complement(4546071..4546412) 1 NC_022657.1 hypothetical protein 4546412 17444846 AFR_20865 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735498.1 4546071 R 1246995 CDS YP_008735499.1 556567074 17444847 complement(4546479..4548044) 1 NC_022657.1 hypothetical protein 4548044 17444847 AFR_20870 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735499.1 4546479 R 1246995 CDS YP_008735500.1 556567075 17444848 complement(4548337..4549023) 1 NC_022657.1 putative sortase family protein 4549023 17444848 AFR_20875 Actinoplanes friuliensis DSM 7358 putative sortase family protein YP_008735500.1 4548337 R 1246995 CDS YP_008735501.1 556567076 17444849 complement(4549026..4549838) 1 NC_022657.1 hypothetical protein 4549838 17444849 AFR_20880 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735501.1 4549026 R 1246995 CDS YP_008735502.1 556567077 17444850 4549979..4550551 1 NC_022657.1 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; putative RNA polymerase ECF-subfamily sigma factor 4550551 17444850 AFR_20885 Actinoplanes friuliensis DSM 7358 putative RNA polymerase ECF-subfamily sigma factor YP_008735502.1 4549979 D 1246995 CDS YP_008735503.1 556567078 17444851 4550505..4551203 1 NC_022657.1 hypothetical protein 4551203 17444851 AFR_20890 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735503.1 4550505 D 1246995 CDS YP_008735504.1 556567079 17444852 complement(4551292..4553298) 1 NC_022657.1 COG2409 Predicted drug exporters of the RND superfamily; hypothetical protein 4553298 17444852 AFR_20895 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735504.1 4551292 R 1246995 CDS YP_008735505.1 556567080 17444853 4553387..4553881 1 NC_022657.1 COG1846 Transcriptional regulators; putative MarR-family transcriptional regulator 4553881 17444853 AFR_20900 Actinoplanes friuliensis DSM 7358 putative MarR-family transcriptional regulator YP_008735505.1 4553387 D 1246995 CDS YP_008735506.1 556567081 17444854 complement(4553926..4554594) 1 NC_022657.1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; two-component system response regulator 4554594 17444854 AFR_20905 Actinoplanes friuliensis DSM 7358 two-component system response regulator YP_008735506.1 4553926 R 1246995 CDS YP_008735507.1 556567082 17444855 complement(4554591..4555541) 1 NC_022657.1 COG4585 Signal transduction histidine kinase; histidine kinase 4555541 17444855 AFR_20910 Actinoplanes friuliensis DSM 7358 histidine kinase YP_008735507.1 4554591 R 1246995 CDS YP_008735508.1 556567083 17444856 4555653..4556360 1 NC_022657.1 COG1131 ABC-type multidrug transport system, ATPase component; ABC transporter-like protein 4556360 17444856 AFR_20915 Actinoplanes friuliensis DSM 7358 ABC transporter-like protein YP_008735508.1 4555653 D 1246995 CDS YP_008735509.1 556567084 17444857 4556354..4557031 1 NC_022657.1 hypothetical protein 4557031 17444857 AFR_20920 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735509.1 4556354 D 1246995 CDS YP_008735510.1 556567085 17444858 4557028..4557531 1 NC_022657.1 hypothetical protein 4557531 17444858 AFR_20925 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735510.1 4557028 D 1246995 CDS YP_008735511.1 556567086 17444859 4557582..4558679 1 NC_022657.1 COG1680 Beta-lactamase class C and other penicillin binding proteins; esterase 4558679 17444859 AFR_20930 Actinoplanes friuliensis DSM 7358 esterase YP_008735511.1 4557582 D 1246995 CDS YP_008735512.1 556567087 17444860 4558761..4559900 1 NC_022657.1 COG1840 ABC-type Fe3+ transport system, periplasmic component; putative ABC transporter substrate-binding protein 4559900 17444860 AFR_20935 Actinoplanes friuliensis DSM 7358 putative ABC transporter substrate-binding protein YP_008735512.1 4558761 D 1246995 CDS YP_008735513.1 556567088 17444861 4559903..4560823 1 NC_022657.1 COG4132 ABC-type uncharacterized transport system, permease component; ABC transporter permease 4560823 17444861 AFR_20940 Actinoplanes friuliensis DSM 7358 ABC transporter permease YP_008735513.1 4559903 D 1246995 CDS YP_008735514.1 556567089 17444862 4560811..4561605 1 NC_022657.1 COG1177 ABC-type spermidine/putrescine transport system, permease component II; ABC transporter permease 4561605 17444862 AFR_20945 Actinoplanes friuliensis DSM 7358 ABC transporter permease YP_008735514.1 4560811 D 1246995 CDS YP_008735515.1 556567090 17444863 4561602..4562624 1 NC_022657.1 COG3842 ABC-type spermidine/putrescine transport systems, ATPase components; putative ABC transporter ATP-binding protein 4562624 17444863 AFR_20950 Actinoplanes friuliensis DSM 7358 putative ABC transporter ATP-binding protein YP_008735515.1 4561602 D 1246995 CDS YP_008735516.1 556567091 17444864 4562673..4563068 1 NC_022657.1 hypothetical protein 4563068 17444864 AFR_20955 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735516.1 4562673 D 1246995 CDS YP_008735517.1 556567092 17444865 4563091..4564146 1 NC_022657.1 Clp domain-containing protein 4564146 17444865 AFR_20960 Actinoplanes friuliensis DSM 7358 Clp domain-containing protein YP_008735517.1 4563091 D 1246995 CDS YP_008735518.1 556567093 17444866 4564151..4565374 1 NC_022657.1 COG0477 Permeases of the major facilitator superfamily; major facilitator transporter 4565374 17444866 AFR_20965 Actinoplanes friuliensis DSM 7358 major facilitator transporter YP_008735518.1 4564151 D 1246995 CDS YP_008735519.1 556567094 17444867 4565371..4566645 1 NC_022657.1 hypothetical protein 4566645 17444867 AFR_20970 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735519.1 4565371 D 1246995 CDS YP_008735520.1 556567095 17444868 4566694..4567377 1 NC_022657.1 hypothetical protein 4567377 17444868 AFR_20975 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735520.1 4566694 D 1246995 CDS YP_008735521.1 556567096 17444869 complement(4567367..4568056) 1 NC_022657.1 COG3979 Uncharacterized protein contain chitin-binding domain type 3; chitinase 4568056 17444869 AFR_20980 Actinoplanes friuliensis DSM 7358 chitinase YP_008735521.1 4567367 R 1246995 CDS YP_008735522.1 556567097 17444870 4568492..4568695 1 NC_022657.1 hypothetical protein 4568695 17444870 AFR_20985 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735522.1 4568492 D 1246995 CDS YP_008735523.1 556567098 17444871 4568747..4570153 1 NC_022657.1 hypothetical protein 4570153 17444871 AFR_20990 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735523.1 4568747 D 1246995 CDS YP_008735524.1 556567099 17444872 4570150..4570491 1 NC_022657.1 hypothetical protein 4570491 17444872 AFR_20995 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735524.1 4570150 D 1246995 CDS YP_008735525.1 556567100 17444873 4570529..4571554 1 NC_022657.1 COG2207 AraC-type DNA-binding domain-containing proteins; putative AraC-family transcriptional regulator 4571554 17444873 AFR_21000 Actinoplanes friuliensis DSM 7358 putative AraC-family transcriptional regulator YP_008735525.1 4570529 D 1246995 CDS YP_008735526.1 556567101 17444874 4571853..4572122 1 NC_022657.1 hypothetical protein 4572122 17444874 AFR_21005 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735526.1 4571853 D 1246995 CDS YP_008735527.1 556567102 17444875 4572338..4572577 1 NC_022657.1 hypothetical protein 4572577 17444875 AFR_21010 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735527.1 4572338 D 1246995 CDS YP_008735528.1 556567103 17444876 complement(4572588..4573607) 1 NC_022657.1 hypothetical protein 4573607 17444876 AFR_21015 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735528.1 4572588 R 1246995 CDS YP_008735529.1 556567104 17444877 complement(4573864..4575096) 1 NC_022657.1 COG0448 ADP-glucose pyrophosphorylase; glucose-1-phosphate adenylyltransferase 4575096 glgC 17444877 glgC Actinoplanes friuliensis DSM 7358 glucose-1-phosphate adenylyltransferase YP_008735529.1 4573864 R 1246995 CDS YP_008735530.1 556567105 17444878 4575157..4576380 1 NC_022657.1 COG0438 Glycosyltransferase; putative glycosyltransferase 4576380 17444878 AFR_21025 Actinoplanes friuliensis DSM 7358 putative glycosyltransferase YP_008735530.1 4575157 D 1246995 CDS YP_008735531.1 556567106 17444879 complement(4576362..4577261) 1 NC_022657.1 COG3380 Predicted NAD/FAD-dependent oxidoreductase; hypothetical protein 4577261 17444879 AFR_21030 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735531.1 4576362 R 1246995 CDS YP_008735532.1 556567107 17444880 4577294..4578916 1 NC_022657.1 COG1649 Uncharacterized protein conserved in bacteria; hypothetical protein 4578916 17444880 AFR_21035 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735532.1 4577294 D 1246995 CDS YP_008735533.1 556567108 17444881 complement(4578906..4580540) 1 NC_022657.1 COG0488 ATPase components of ABC transporters with duplicated ATPase domains; ABC transporter related protein 4580540 17444881 AFR_21040 Actinoplanes friuliensis DSM 7358 ABC transporter related protein YP_008735533.1 4578906 R 1246995 CDS YP_008735534.1 556567109 17444882 complement(4580564..4581394) 1 NC_022657.1 COG0384 Predicted epimerase, PhzC/PhzF homolog; putative phenazine biosynthesis-like protein 4581394 17444882 AFR_21045 Actinoplanes friuliensis DSM 7358 putative phenazine biosynthesis-like protein YP_008735534.1 4580564 R 1246995 CDS YP_008735535.1 556567110 17444883 4581528..4582922 1 NC_022657.1 COG1239 Mg-chelatase subunit ChlI; magnesium chelatase subunit I 4582922 17444883 AFR_21050 Actinoplanes friuliensis DSM 7358 magnesium chelatase subunit I YP_008735535.1 4581528 D 1246995 CDS YP_008735536.1 556567111 17444884 4582925..4584886 1 NC_022657.1 COG4867 Uncharacterized protein with a von Willebrand factor type A (vWA) domain; von Willebrand factor type A 4584886 17444884 AFR_21055 Actinoplanes friuliensis DSM 7358 von Willebrand factor type A YP_008735536.1 4582925 D 1246995 CDS YP_008735537.1 556567112 17444885 4585156..4585800 1 NC_022657.1 COG0558 Phosphatidylglycerophosphate synthase; CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 4585800 17444885 AFR_21060 Actinoplanes friuliensis DSM 7358 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase YP_008735537.1 4585156 D 1246995 CDS YP_008735538.1 556567113 17444886 4585797..4586687 1 NC_022657.1 COG3879 Uncharacterized protein conserved in bacteria; hypothetical protein 4586687 17444886 AFR_21065 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735538.1 4585797 D 1246995 CDS YP_008735539.1 556567114 17444887 4586687..4587019 1 NC_022657.1 COG3856 Uncharacterized conserved protein (small basic protein); hypothetical protein 4587019 17444887 AFR_21070 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735539.1 4586687 D 1246995 CDS YP_008735540.1 556567115 17444888 4588109..4589296 1 NC_022657.1 COG3879 Uncharacterized protein conserved in bacteria; hypothetical protein 4589296 17444888 AFR_21075 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735540.1 4588109 D 1246995 CDS YP_008735541.1 556567116 17444889 4589325..4589705 1 NC_022657.1 COG0509 Glycine cleavage system H protein (lipoate-binding); putative glycine cleavage system H protein 4589705 17444889 AFR_21080 Actinoplanes friuliensis DSM 7358 putative glycine cleavage system H protein YP_008735541.1 4589325 D 1246995 CDS YP_008735542.1 556567117 17444890 4589908..4590360 1 NC_022657.1 COG1716 FOG: FHA domain; hypothetical protein 4590360 17444890 AFR_21085 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735542.1 4589908 D 1246995 CDS YP_008735543.1 556567118 17444891 4590357..4591109 1 NC_022657.1 COG0789 Predicted transcriptional regulators; putative HTH-type transcriptional regulator 4591109 17444891 AFR_21090 Actinoplanes friuliensis DSM 7358 putative HTH-type transcriptional regulator YP_008735543.1 4590357 D 1246995 CDS YP_008735544.1 556567119 17444892 4591249..4591713 1 NC_022657.1 COG1259 Uncharacterized conserved protein; hypothetical protein 4591713 17444892 AFR_21095 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735544.1 4591249 D 1246995 CDS YP_008735545.1 556567120 17444893 4591956..4592447 1 NC_022657.1 COG0789 Predicted transcriptional regulators; hypothetical protein 4592447 17444893 AFR_21100 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735545.1 4591956 D 1246995 CDS YP_008735546.1 556567121 17444894 4592437..4594701 1 NC_022657.1 COG0178 Excinuclease ATPase subunit; UvrABC system protein A 4594701 17444894 AFR_21105 Actinoplanes friuliensis DSM 7358 UvrABC system protein A YP_008735546.1 4592437 D 1246995 CDS YP_008735547.1 556567122 17444895 4594762..4595382 1 NC_022657.1 COG0500 SAM-dependent methyltransferases; methyltransferase small 4595382 17444895 AFR_21110 Actinoplanes friuliensis DSM 7358 methyltransferase small YP_008735547.1 4594762 D 1246995 CDS YP_008735548.1 556567123 17444896 4595411..4596997 1 NC_022657.1 COG2202 FOG: PAS/PAC domain; Stage II sporulation protein E (SpoIIE) 4596997 17444896 AFR_21115 Actinoplanes friuliensis DSM 7358 Stage II sporulation protein E (SpoIIE) YP_008735548.1 4595411 D 1246995 CDS YP_008735549.1 556567124 17444897 complement(4596998..4597861) 1 NC_022657.1 COG0583 Transcriptional regulator; LysR family transcriptional regulator 4597861 17444897 AFR_21120 Actinoplanes friuliensis DSM 7358 LysR family transcriptional regulator YP_008735549.1 4596998 R 1246995 CDS YP_008735550.1 556567125 17444898 4597944..4598843 1 NC_022657.1 COG5006 Predicted permease, DMT superfamily; amino acid efflux protein 4598843 17444898 AFR_21125 Actinoplanes friuliensis DSM 7358 amino acid efflux protein YP_008735550.1 4597944 D 1246995 CDS YP_008735551.1 556567126 17444899 complement(4598793..4599092) 1 NC_022657.1 COG1278 Cold shock proteins; hypothetical protein 4599092 17444899 AFR_21130 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735551.1 4598793 R 1246995 CDS YP_008735552.1 556567127 17444900 complement(4599107..4599952) 1 NC_022657.1 COG0500 SAM-dependent methyltransferases; type 12 methyltransferase 4599952 17444900 AFR_21135 Actinoplanes friuliensis DSM 7358 type 12 methyltransferase YP_008735552.1 4599107 R 1246995 CDS YP_008735553.1 556567128 17444901 4600057..4600569 1 NC_022657.1 COG1396 Predicted transcriptional regulators; transcriptional regulator 4600569 17444901 AFR_21140 Actinoplanes friuliensis DSM 7358 transcriptional regulator YP_008735553.1 4600057 D 1246995 CDS YP_008735554.1 556567129 17444902 complement(4600766..4601503) 1 NC_022657.1 hypothetical protein 4601503 17444902 AFR_21145 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735554.1 4600766 R 1246995 CDS YP_008735555.1 556567130 17444903 complement(4601545..4603464) 1 NC_022657.1 COG0367 Asparagine synthase (glutamine-hydrolyzing); putative asparagine synthetase 4603464 17444903 AFR_21150 Actinoplanes friuliensis DSM 7358 putative asparagine synthetase YP_008735555.1 4601545 R 1246995 CDS YP_008735556.1 556567131 17444904 4603595..4604314 1 NC_022657.1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; putative two-component system response regulator 4604314 17444904 AFR_21155 Actinoplanes friuliensis DSM 7358 putative two-component system response regulator YP_008735556.1 4603595 D 1246995 CDS YP_008735557.1 556567132 17444905 4604311..4606092 1 NC_022657.1 COG0642 Signal transduction histidine kinase; histidine kinase 4606092 17444905 AFR_21160 Actinoplanes friuliensis DSM 7358 histidine kinase YP_008735557.1 4604311 D 1246995 CDS YP_008735558.1 556567133 17444906 complement(4606070..4608568) 1 NC_022657.1 COG4581 Superfamily II RNA helicase; putative DEAD/DEAH box helicase 4608568 17444906 AFR_21165 Actinoplanes friuliensis DSM 7358 putative DEAD/DEAH box helicase YP_008735558.1 4606070 R 1246995 CDS YP_008735559.1 556567134 17444907 complement(4609063..4609707) 1 NC_022657.1 hypothetical protein 4609707 17444907 AFR_21170 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735559.1 4609063 R 1246995 CDS YP_008735560.1 556567135 17444908 complement(4611111..4611491) 1 NC_022657.1 hypothetical protein 4611491 17444908 AFR_21175 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735560.1 4611111 R 1246995 CDS YP_008735561.1 556567136 17444909 complement(4611563..4612309) 1 NC_022657.1 COG3541 Predicted nucleotidyltransferase; hypothetical protein 4612309 17444909 AFR_21180 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735561.1 4611563 R 1246995 CDS YP_008735562.1 556567137 17444910 complement(4612306..4612980) 1 NC_022657.1 COG3541 Predicted nucleotidyltransferase; hypothetical protein 4612980 17444910 AFR_21185 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735562.1 4612306 R 1246995 CDS YP_008735563.1 556567138 17444911 complement(4612990..4613985) 1 NC_022657.1 COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases); putative aldo/keto reductase 4613985 17444911 AFR_21190 Actinoplanes friuliensis DSM 7358 putative aldo/keto reductase YP_008735563.1 4612990 R 1246995 CDS YP_008735564.1 556567139 17444912 4614223..4617027 1 NC_022657.1 COG0403 Glycine cleavage system protein P (pyridoxal-binding), N-terminal domain; glycine dehydrogenase 4617027 17444912 AFR_21195 Actinoplanes friuliensis DSM 7358 glycine dehydrogenase YP_008735564.1 4614223 D 1246995 CDS YP_008735565.1 556567140 17444913 complement(4617129..4617329) 1 NC_022657.1 hypothetical protein 4617329 17444913 AFR_21200 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735565.1 4617129 R 1246995 CDS YP_008735566.1 556567141 17444914 4617836..4618717 1 NC_022657.1 COG0147 Anthranilate/para-aminobenzoate synthases component I; putative chorismate-binding protein 4618717 17444914 AFR_21205 Actinoplanes friuliensis DSM 7358 putative chorismate-binding protein YP_008735566.1 4617836 D 1246995 CDS YP_008735567.1 556567142 17444915 complement(4618698..4619783) 1 NC_022657.1 hypothetical protein 4619783 17444915 AFR_21210 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735567.1 4618698 R 1246995 CDS YP_008735568.1 556567143 17444916 4619912..4620646 1 NC_022657.1 hypothetical protein 4620646 17444916 AFR_21215 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735568.1 4619912 D 1246995 CDS YP_008735569.1 556567144 17444917 4620658..4621149 1 NC_022657.1 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; RNA polymerase sigma-E factor 4621149 17444917 AFR_21220 Actinoplanes friuliensis DSM 7358 RNA polymerase sigma-E factor YP_008735569.1 4620658 D 1246995 CDS YP_008735570.1 556567145 17444918 4621164..4621661 1 NC_022657.1 COG0242 N-formylmethionyl-tRNA deformylase; peptide deformylase 4621661 17444918 AFR_21225 Actinoplanes friuliensis DSM 7358 peptide deformylase YP_008735570.1 4621164 D 1246995 CDS YP_008735571.1 556567146 17444919 4621658..4622314 1 NC_022657.1 COG0500 SAM-dependent methyltransferases; methyltransferase type 12 4622314 17444919 AFR_21230 Actinoplanes friuliensis DSM 7358 methyltransferase type 12 YP_008735571.1 4621658 D 1246995 CDS YP_008735572.1 556567147 17444920 complement(4622338..4622781) 1 NC_022657.1 COG1051 ADP-ribose pyrophosphatase; NUDIX hydrolase 4622781 17444920 AFR_21235 Actinoplanes friuliensis DSM 7358 NUDIX hydrolase YP_008735572.1 4622338 R 1246995 CDS YP_008735573.1 556567148 17444921 complement(4622783..4623931) 1 NC_022657.1 COG0019 Diaminopimelate decarboxylase; putative diaminopimelate decarboxylase 4623931 17444921 AFR_21240 Actinoplanes friuliensis DSM 7358 putative diaminopimelate decarboxylase YP_008735573.1 4622783 R 1246995 CDS YP_008735574.1 556567149 17444922 complement(4623918..4625537) 1 NC_022657.1 COG4264 Siderophore synthetase component; hypothetical protein 4625537 17444922 AFR_21245 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735574.1 4623918 R 1246995 CDS YP_008735575.1 556567150 17444923 complement(4625534..4627309) 1 NC_022657.1 COG4264 Siderophore synthetase component; hypothetical protein 4627309 17444923 AFR_21250 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735575.1 4625534 R 1246995 CDS YP_008735576.1 556567151 17444924 complement(4628741..4629721) 1 NC_022657.1 COG0451 Nucleoside-diphosphate-sugar epimerases; putative reductase 4629721 17444924 AFR_21255 Actinoplanes friuliensis DSM 7358 putative reductase YP_008735576.1 4628741 R 1246995 CDS YP_008735577.1 556567152 17444925 4629647..4630207 1 NC_022657.1 hypothetical protein 4630207 17444925 AFR_21260 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735577.1 4629647 D 1246995 CDS YP_008735578.1 556567153 17444926 4630346..4631215 1 NC_022657.1 COG1131 ABC-type multidrug transport system, ATPase component; antibiotic transport system ATP-binding protein 4631215 17444926 AFR_21265 Actinoplanes friuliensis DSM 7358 antibiotic transport system ATP-binding protein YP_008735578.1 4630346 D 1246995 CDS YP_008735579.1 556567154 17444927 4631212..4631997 1 NC_022657.1 COG0842 ABC-type multidrug transport system, permease component; ABC transporter permease 4631997 17444927 AFR_21270 Actinoplanes friuliensis DSM 7358 ABC transporter permease YP_008735579.1 4631212 D 1246995 CDS YP_008735580.1 556567155 17444928 4632019..4633119 1 NC_022657.1 COG4585 Signal transduction histidine kinase; putative two-component system sensor kinase 4633119 17444928 AFR_21275 Actinoplanes friuliensis DSM 7358 putative two-component system sensor kinase YP_008735580.1 4632019 D 1246995 CDS YP_008735581.1 556567156 17444929 4633116..4633727 1 NC_022657.1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; yfiK-like transcriptional regulatory protein 4633727 17444929 AFR_21280 Actinoplanes friuliensis DSM 7358 yfiK-like transcriptional regulatory protein YP_008735581.1 4633116 D 1246995 CDS YP_008735582.1 556567157 17444930 4633872..4634732 1 NC_022657.1 COG1191 DNA-directed RNA polymerase specialized sigma subunit; RNA polymerase sigma factor rpoD 4634732 17444930 AFR_21285 Actinoplanes friuliensis DSM 7358 RNA polymerase sigma factor rpoD YP_008735582.1 4633872 D 1246995 CDS YP_008735583.1 556567158 17444931 complement(4634720..4635760) 1 NC_022657.1 hypothetical protein 4635760 17444931 AFR_21290 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735583.1 4634720 R 1246995 CDS YP_008735584.1 556567159 17444932 complement(4635757..4636098) 1 NC_022657.1 COG1695 Predicted transcriptional regulators; putative PadR-like family transcriptional regulator 4636098 17444932 AFR_21295 Actinoplanes friuliensis DSM 7358 putative PadR-like family transcriptional regulator YP_008735584.1 4635757 R 1246995 CDS YP_008735585.1 556567160 17444933 4636316..4637908 1 NC_022657.1 COG0488 ATPase components of ABC transporters with duplicated ATPase domains; Ribose import ATP-binding protein rbsA 4637908 17444933 AFR_21300 Actinoplanes friuliensis DSM 7358 Ribose import ATP-binding protein rbsA YP_008735585.1 4636316 D 1246995 CDS YP_008735586.1 556567161 17444934 4637922..4638893 1 NC_022657.1 COG4974 Site-specific recombinase XerD; integrase family protein 4638893 17444934 AFR_21305 Actinoplanes friuliensis DSM 7358 integrase family protein YP_008735586.1 4637922 D 1246995 CDS YP_008735587.1 556567162 17444935 4638949..4639794 1 NC_022657.1 COG1968 Uncharacterized bacitracin resistance protein; undecaprenyl pyrophosphate phosphatase 4639794 17444935 AFR_21310 Actinoplanes friuliensis DSM 7358 undecaprenyl pyrophosphate phosphatase YP_008735587.1 4638949 D 1246995 CDS YP_008735588.1 556567163 17444936 4639791..4640693 1 NC_022657.1 hypothetical protein 4640693 17444936 AFR_21315 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735588.1 4639791 D 1246995 CDS YP_008735589.1 556567164 17444937 4640696..4641673 1 NC_022657.1 hypothetical protein 4641673 17444937 AFR_21320 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735589.1 4640696 D 1246995 CDS YP_008735590.1 556567165 17444938 4641769..4642599 1 NC_022657.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); hydrolase 4642599 17444938 AFR_21325 Actinoplanes friuliensis DSM 7358 hydrolase YP_008735590.1 4641769 D 1246995 CDS YP_008735591.1 556567166 17444939 4642562..4643149 1 NC_022657.1 COG1309 Transcriptional regulator; TetR family transcriptional regulator 4643149 17444939 AFR_21330 Actinoplanes friuliensis DSM 7358 TetR family transcriptional regulator YP_008735591.1 4642562 D 1246995 CDS YP_008735592.1 556567167 17444940 4643239..4644444 1 NC_022657.1 COG2124 Cytochrome P450; cytochrome P450 monooxygenase CYP105B2 4644444 17444940 AFR_21335 Actinoplanes friuliensis DSM 7358 cytochrome P450 monooxygenase CYP105B2 YP_008735592.1 4643239 D 1246995 CDS YP_008735593.1 556567168 17444941 4644441..4644647 1 NC_022657.1 COG1141 Ferredoxin; ferredoxin 4644647 17444941 AFR_21340 Actinoplanes friuliensis DSM 7358 ferredoxin YP_008735593.1 4644441 D 1246995 CDS YP_008735594.1 556567169 17444942 complement(4645434..4645790) 1 NC_022657.1 COG1725 Predicted transcriptional regulators; HTH-type transcriptional repressor yvoA 4645790 17444942 AFR_21355 Actinoplanes friuliensis DSM 7358 HTH-type transcriptional repressor yvoA YP_008735594.1 4645434 R 1246995 CDS YP_008735595.1 556567170 17444943 complement(4645811..4647181) 1 NC_022657.1 COG2270 Permeases of the major facilitator superfamily; putative MFS transporter 4647181 17444943 AFR_21360 Actinoplanes friuliensis DSM 7358 putative MFS transporter YP_008735595.1 4645811 R 1246995 CDS YP_008735596.1 556567171 17444944 4647307..4647702 1 NC_022657.1 hypothetical protein 4647702 17444944 AFR_21365 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735596.1 4647307 D 1246995 CDS YP_008735597.1 556567172 17444945 complement(4647690..4648286) 1 NC_022657.1 hypothetical protein 4648286 17444945 AFR_21370 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735597.1 4647690 R 1246995 CDS YP_008735598.1 556567173 17444946 complement(4648283..4650127) 1 NC_022657.1 COG0699 Predicted GTPases (dynamin-related); hypothetical protein 4650127 17444946 AFR_21375 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735598.1 4648283 R 1246995 CDS YP_008735599.1 556567174 17444947 complement(4650124..4651440) 1 NC_022657.1 hypothetical protein 4651440 17444947 AFR_21380 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735599.1 4650124 R 1246995 CDS YP_008735600.1 556567175 17444948 4651831..4654593 1 NC_022657.1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; transcriptional regulatory protein degU 4654593 17444948 AFR_21385 Actinoplanes friuliensis DSM 7358 transcriptional regulatory protein degU YP_008735600.1 4651831 D 1246995 CDS YP_008735601.1 556567176 17444949 4654590..4655132 1 NC_022657.1 hypothetical protein 4655132 17444949 AFR_21390 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735601.1 4654590 D 1246995 CDS YP_008735602.1 556567177 17444950 complement(4656581..4657357) 1 NC_022657.1 hypothetical protein 4657357 17444950 AFR_21395 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735602.1 4656581 R 1246995 CDS YP_008735603.1 556567178 17444951 4657732..4658295 1 NC_022657.1 COG4332 Uncharacterized protein conserved in bacteria; hypothetical protein 4658295 17444951 AFR_21400 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735603.1 4657732 D 1246995 CDS YP_008735604.1 556567179 17444952 complement(4658316..4658951) 1 NC_022657.1 hypothetical protein 4658951 17444952 AFR_21405 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735604.1 4658316 R 1246995 CDS YP_008735605.1 556567180 17444953 4658977..4659804 1 NC_022657.1 COG2362 D-aminopeptidase; D-aminopeptidase 4659804 17444953 AFR_21410 Actinoplanes friuliensis DSM 7358 D-aminopeptidase YP_008735605.1 4658977 D 1246995 CDS YP_008735606.1 556567181 17444954 complement(4659781..4660533) 1 NC_022657.1 COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase; putative 1-acyl-sn-glycerol-3-phosphate acyltransferase 4660533 17444954 AFR_21415 Actinoplanes friuliensis DSM 7358 putative 1-acyl-sn-glycerol-3-phosphate acyltransferase YP_008735606.1 4659781 R 1246995 CDS YP_008735607.1 556567182 17444955 complement(4660596..4660958) 1 NC_022657.1 hypothetical protein 4660958 17444955 AFR_21420 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735607.1 4660596 R 1246995 CDS YP_008735608.1 556567183 17444956 4660997..4661320 1 NC_022657.1 hypothetical protein 4661320 17444956 AFR_21425 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735608.1 4660997 D 1246995 CDS YP_008735609.1 556567184 17444957 complement(4661376..4662074) 1 NC_022657.1 COG1012 NAD-dependent aldehyde dehydrogenases; hypothetical protein 4662074 17444957 AFR_21430 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735609.1 4661376 R 1246995 CDS YP_008735610.1 556567185 17444958 complement(4662074..4664395) 1 NC_022657.1 COG0457 FOG: TPR repeat; regulatory protein 4664395 17444958 AFR_21435 Actinoplanes friuliensis DSM 7358 regulatory protein YP_008735610.1 4662074 R 1246995 CDS YP_008735611.1 556567186 17444959 complement(4664440..4664865) 1 NC_022657.1 COG1846 Transcriptional regulators; MarR family transcriptional regulator 4664865 17444959 AFR_21440 Actinoplanes friuliensis DSM 7358 MarR family transcriptional regulator YP_008735611.1 4664440 R 1246995 CDS YP_008735612.1 556567187 17444960 complement(4664875..4665663) 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); short-chain dehydrogenase/reductase SDR 4665663 17444960 AFR_21445 Actinoplanes friuliensis DSM 7358 short-chain dehydrogenase/reductase SDR YP_008735612.1 4664875 R 1246995 CDS YP_008735613.1 556567188 17444961 4665766..4666335 1 NC_022657.1 COG1309 Transcriptional regulator; TetR family transcriptional regulator 4666335 17444961 AFR_21450 Actinoplanes friuliensis DSM 7358 TetR family transcriptional regulator YP_008735613.1 4665766 D 1246995 CDS YP_008735614.1 556567189 17444962 complement(4666325..4667737) 1 NC_022657.1 COG0500 SAM-dependent methyltransferases; type 11 methyltransferase 4667737 17444962 AFR_21455 Actinoplanes friuliensis DSM 7358 type 11 methyltransferase YP_008735614.1 4666325 R 1246995 CDS YP_008735615.1 556567190 17444963 4667834..4668442 1 NC_022657.1 COG1309 Transcriptional regulator; TetR family transcriptional regulator 4668442 17444963 AFR_21460 Actinoplanes friuliensis DSM 7358 TetR family transcriptional regulator YP_008735615.1 4667834 D 1246995 CDS YP_008735616.1 556567191 17444964 4668439..4668882 1 NC_022657.1 COG2207 AraC-type DNA-binding domain-containing proteins; putative araC-like transcription regulator 4668882 17444964 AFR_21465 Actinoplanes friuliensis DSM 7358 putative araC-like transcription regulator YP_008735616.1 4668439 D 1246995 CDS YP_008735617.1 556567192 17444965 4668888..4669298 1 NC_022657.1 COG0346 Lactoylglutathione lyase and related lyases; hypothetical protein 4669298 17444965 AFR_21470 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735617.1 4668888 D 1246995 CDS YP_008735618.1 556567193 17444966 4670675..4671625 1 NC_022657.1 COG4974 Site-specific recombinase XerD; integrase family protein 4671625 17444966 AFR_21475 Actinoplanes friuliensis DSM 7358 integrase family protein YP_008735618.1 4670675 D 1246995 CDS YP_008735619.1 556567194 17444967 complement(4671622..4672440) 1 NC_022657.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); alpha/beta hydrolase fold protein 4672440 17444967 AFR_21480 Actinoplanes friuliensis DSM 7358 alpha/beta hydrolase fold protein YP_008735619.1 4671622 R 1246995 CDS YP_008735620.1 556567195 17444968 complement(4672442..4672861) 1 NC_022657.1 COG1764 Predicted redox protein, regulator of disulfide bond formation; hypothetical protein 4672861 17444968 AFR_21485 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735620.1 4672442 R 1246995 CDS YP_008735621.1 556567196 17444969 complement(4672876..4673322) 1 NC_022657.1 COG1846 Transcriptional regulators; putative MarR-family transcriptional regulator 4673322 17444969 AFR_21490 Actinoplanes friuliensis DSM 7358 putative MarR-family transcriptional regulator YP_008735621.1 4672876 R 1246995 CDS YP_008735622.1 556567197 17444970 4673399..4673893 1 NC_022657.1 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins; yjdG-like N-acetyltransferase 4673893 17444970 AFR_21495 Actinoplanes friuliensis DSM 7358 yjdG-like N-acetyltransferase YP_008735622.1 4673399 D 1246995 CDS YP_008735623.1 556567198 17444971 complement(4673890..4674681) 1 NC_022657.1 COG3568 Metal-dependent hydrolase; hypothetical protein 4674681 17444971 AFR_21500 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735623.1 4673890 R 1246995 CDS YP_008735624.1 556567199 17444972 4674821..4675300 1 NC_022657.1 COG4702 Uncharacterized conserved protein; hypothetical protein 4675300 17444972 AFR_21505 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735624.1 4674821 D 1246995 CDS YP_008735625.1 556567200 17444973 complement(4675293..4677197) 1 NC_022657.1 COG0480 Translation elongation factors (GTPases); tetracycline resistance protein 4677197 17444973 AFR_21510 Actinoplanes friuliensis DSM 7358 tetracycline resistance protein YP_008735625.1 4675293 R 1246995 CDS YP_008735626.1 556567201 17444974 4677356..4677745 1 NC_022657.1 hypothetical protein 4677745 17444974 AFR_21515 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735626.1 4677356 D 1246995 CDS YP_008735627.1 556567202 17444975 4677742..4678236 1 NC_022657.1 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins; acetyltransferase 4678236 17444975 AFR_21520 Actinoplanes friuliensis DSM 7358 acetyltransferase YP_008735627.1 4677742 D 1246995 CDS YP_008735628.1 556567203 17444976 complement(4678151..4679008) 1 NC_022657.1 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases; hypothetical protein 4679008 17444976 AFR_21525 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735628.1 4678151 R 1246995 CDS YP_008735629.1 556567204 17444977 complement(4679005..4679364) 1 NC_022657.1 hypothetical protein 4679364 17444977 AFR_21530 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735629.1 4679005 R 1246995 CDS YP_008735630.1 556567205 17444978 complement(4679414..4681093) 1 NC_022657.1 hypothetical protein 4681093 17444978 AFR_21535 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735630.1 4679414 R 1246995 CDS YP_008735631.1 556567206 17444979 4681169..4682092 1 NC_022657.1 COG4427 Uncharacterized protein conserved in bacteria; hypothetical protein 4682092 17444979 AFR_21540 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735631.1 4681169 D 1246995 CDS YP_008735632.1 556567207 17444980 4682135..4682917 1 NC_022657.1 hypothetical protein 4682917 17444980 AFR_21545 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735632.1 4682135 D 1246995 CDS YP_008735633.1 556567208 17444981 4683053..4684552 1 NC_022657.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); hypothetical protein 4684552 17444981 AFR_21550 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735633.1 4683053 D 1246995 CDS YP_008735634.1 556567209 17444982 4684578..4685789 1 NC_022657.1 COG4585 Signal transduction histidine kinase; two-component system histidine kinase 4685789 17444982 AFR_21555 Actinoplanes friuliensis DSM 7358 two-component system histidine kinase YP_008735634.1 4684578 D 1246995 CDS YP_008735635.1 556567210 17444983 4685786..4686442 1 NC_022657.1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; two-component system response regulator 4686442 17444983 AFR_21560 Actinoplanes friuliensis DSM 7358 two-component system response regulator YP_008735635.1 4685786 D 1246995 CDS YP_008735636.1 556567211 17444984 complement(4686421..4686939) 1 NC_022657.1 COG3467 Predicted flavin-nucleotide-binding protein; hypothetical protein 4686939 17444984 AFR_21565 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735636.1 4686421 R 1246995 CDS YP_008735637.1 556567212 17444985 complement(4687022..4687738) 1 NC_022657.1 hypothetical protein 4687738 17444985 AFR_21570 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735637.1 4687022 R 1246995 CDS YP_008735638.1 556567213 17444986 4687871..4688968 1 NC_022657.1 COG4585 Signal transduction histidine kinase; histidine kinase 4688968 17444986 AFR_21575 Actinoplanes friuliensis DSM 7358 histidine kinase YP_008735638.1 4687871 D 1246995 CDS YP_008735639.1 556567214 17444987 4688965..4689645 1 NC_022657.1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; transcriptional regulatory protein degU 4689645 17444987 AFR_21580 Actinoplanes friuliensis DSM 7358 transcriptional regulatory protein degU YP_008735639.1 4688965 D 1246995 CDS YP_008735640.1 556567215 17444988 complement(4689658..4690689) 1 NC_022657.1 hypothetical protein 4690689 17444988 AFR_21585 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735640.1 4689658 R 1246995 CDS YP_008735641.1 556567216 17444989 4690970..4691722 1 NC_022657.1 COG0500 SAM-dependent methyltransferases; methyltransferase 4691722 17444989 AFR_21590 Actinoplanes friuliensis DSM 7358 methyltransferase YP_008735641.1 4690970 D 1246995 CDS YP_008735642.1 556567217 17444990 complement(4691759..4692739) 1 NC_022657.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); proline iminopeptidase 4692739 17444990 AFR_21595 Actinoplanes friuliensis DSM 7358 proline iminopeptidase YP_008735642.1 4691759 R 1246995 CDS YP_008735643.1 556567218 17444991 4692891..4694384 1 NC_022657.1 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases; FAD-dependent monooxygenase 4694384 17444991 AFR_21600 Actinoplanes friuliensis DSM 7358 FAD-dependent monooxygenase YP_008735643.1 4692891 D 1246995 CDS YP_008735644.1 556567219 17444992 complement(4694286..4695458) 1 NC_022657.1 COG2312 Erythromycin esterase homolog; hypothetical protein 4695458 17444992 AFR_21605 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735644.1 4694286 R 1246995 CDS YP_008735645.1 556567220 17444993 4695517..4696230 1 NC_022657.1 COG0789 Predicted transcriptional regulators; MerR family transcriptional regulator 4696230 17444993 AFR_21610 Actinoplanes friuliensis DSM 7358 MerR family transcriptional regulator YP_008735645.1 4695517 D 1246995 CDS YP_008735646.1 556567221 17444994 4696227..4696586 1 NC_022657.1 hypothetical protein 4696586 17444994 AFR_21615 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735646.1 4696227 D 1246995 CDS YP_008735647.1 556567222 17444995 4696579..4696851 1 NC_022657.1 COG1011 Predicted hydrolase (HAD superfamily); hydrolase 4696851 17444995 AFR_21620 Actinoplanes friuliensis DSM 7358 hydrolase YP_008735647.1 4696579 D 1246995 CDS YP_008735648.1 556567223 17444996 complement(4696844..4697410) 1 NC_022657.1 COG0412 Dienelactone hydrolase and related enzymes; hypothetical protein 4697410 17444996 AFR_21625 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735648.1 4696844 R 1246995 CDS YP_008735649.1 556567224 17444997 complement(4697407..4698324) 1 NC_022657.1 COG0583 Transcriptional regulator; LysR family transcriptional regulator 4698324 17444997 AFR_21630 Actinoplanes friuliensis DSM 7358 LysR family transcriptional regulator YP_008735649.1 4697407 R 1246995 CDS YP_008735650.1 556567225 17444998 4698368..4699435 1 NC_022657.1 COG0329 Dihydrodipicolinate synthase/N-acetylneuraminate lyase; dihydrodipicolinate synthase 4699435 17444998 AFR_21635 Actinoplanes friuliensis DSM 7358 dihydrodipicolinate synthase YP_008735650.1 4698368 D 1246995 CDS YP_008735651.1 556567226 17444999 complement(4699217..4700326) 1 NC_022657.1 COG1680 Beta-lactamase class C and other penicillin binding proteins; beta-lactamase 4700326 17444999 AFR_21640 Actinoplanes friuliensis DSM 7358 beta-lactamase YP_008735651.1 4699217 R 1246995 CDS YP_008735652.1 556567227 17445000 complement(4700338..4702524) 1 NC_022657.1 COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain; hypothetical protein 4702524 17445000 AFR_21645 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735652.1 4700338 R 1246995 CDS YP_008735653.1 556567228 17445001 complement(4702535..4703701) 1 NC_022657.1 COG3287 Uncharacterized conserved protein; hypothetical protein 4703701 17445001 AFR_21650 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735653.1 4702535 R 1246995 CDS YP_008735654.1 556567229 17445002 4703858..4704178 1 NC_022657.1 COG2076 Membrane transporters of cations and cationic drugs; small multidrug resistance protein 4704178 17445002 AFR_21655 Actinoplanes friuliensis DSM 7358 small multidrug resistance protein YP_008735654.1 4703858 D 1246995 CDS YP_008735655.1 556567230 17445003 4704175..4704711 1 NC_022657.1 COG3226 Uncharacterized protein conserved in bacteria; HTH-type transcriptional regulator betI 4704711 17445003 AFR_21660 Actinoplanes friuliensis DSM 7358 HTH-type transcriptional regulator betI YP_008735655.1 4704175 D 1246995 CDS YP_008735656.1 556567231 17445004 4704798..4705820 1 NC_022657.1 COG1609 Transcriptional regulators; LacI family transcriptional regulator 4705820 17445004 AFR_21665 Actinoplanes friuliensis DSM 7358 LacI family transcriptional regulator YP_008735656.1 4704798 D 1246995 CDS YP_008735657.1 556567232 17445005 4705850..4707085 1 NC_022657.1 COG1653 ABC-type sugar transport system, periplasmic component; family 1 extracellular solute-binding protein 4707085 17445005 AFR_21670 Actinoplanes friuliensis DSM 7358 family 1 extracellular solute-binding protein YP_008735657.1 4705850 D 1246995 CDS YP_008735658.1 556567233 17445006 4707087..4708031 1 NC_022657.1 COG1175 ABC-type sugar transport systems, permease components; binding-protein-dependent transport system inner membrane protein 4708031 17445006 AFR_21675 Actinoplanes friuliensis DSM 7358 binding-protein-dependent transport system inner membrane protein YP_008735658.1 4707087 D 1246995 CDS YP_008735659.1 556567234 17445007 4708035..4708889 1 NC_022657.1 COG0395 ABC-type sugar transport system, permease component; monosaccharide-transporting ATPase 4708889 17445007 AFR_21680 Actinoplanes friuliensis DSM 7358 monosaccharide-transporting ATPase YP_008735659.1 4708035 D 1246995 CDS YP_008735660.1 556567235 17445008 4708899..4710413 1 NC_022657.1 COG3459 Cellobiose phosphorylase; hypothetical protein 4710413 17445008 AFR_21685 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735660.1 4708899 D 1246995 CDS YP_008735661.1 556567236 17445009 4710413..4712212 1 NC_022657.1 COG3664 Beta-xylosidase; Xylan 1,4-beta-xylosidase 4712212 17445009 AFR_21690 Actinoplanes friuliensis DSM 7358 Xylan 1,4-beta-xylosidase YP_008735661.1 4710413 D 1246995 CDS YP_008735662.1 556567237 17445010 complement(4712203..4712871) 1 NC_022657.1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; two-component system response regulator 4712871 17445010 AFR_21695 Actinoplanes friuliensis DSM 7358 two-component system response regulator YP_008735662.1 4712203 R 1246995 CDS YP_008735663.1 556567238 17445011 complement(4712868..4713989) 1 NC_022657.1 COG4585 Signal transduction histidine kinase; putative two-component system sensor kinase 4713989 17445011 AFR_21700 Actinoplanes friuliensis DSM 7358 putative two-component system sensor kinase YP_008735663.1 4712868 R 1246995 CDS YP_008735664.1 556567239 17445012 4714202..4714597 1 NC_022657.1 hypothetical protein 4714597 17445012 AFR_21705 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735664.1 4714202 D 1246995 CDS YP_008735665.1 556567240 17445013 complement(4714510..4715046) 1 NC_022657.1 COG0513 Superfamily II DNA and RNA helicases; hypothetical protein 4715046 17445013 AFR_21710 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735665.1 4714510 R 1246995 CDS YP_008735666.1 556567241 17445014 complement(4715043..4715924) 1 NC_022657.1 COG4257 Streptogramin lyase; hydrolase 4715924 17445014 AFR_21715 Actinoplanes friuliensis DSM 7358 hydrolase YP_008735666.1 4715043 R 1246995 CDS YP_008735667.1 556567242 17445015 complement(4715972..4717186) 1 NC_022657.1 COG1404 Subtilisin-like serine proteases; peptidase S8 and S53 subtilisin kexin sedolisin 4717186 17445015 AFR_21720 Actinoplanes friuliensis DSM 7358 peptidase S8 and S53 subtilisin kexin sedolisin YP_008735667.1 4715972 R 1246995 CDS YP_008735668.1 556567243 17445016 4717444..4717647 1 NC_022657.1 hypothetical protein 4717647 17445016 AFR_21725 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735668.1 4717444 D 1246995 CDS YP_008735669.1 556567244 17445017 4717638..4718432 1 NC_022657.1 hypothetical protein 4718432 17445017 AFR_21730 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735669.1 4717638 D 1246995 CDS YP_008735670.1 556567245 17445018 4718429..4718989 1 NC_022657.1 COG0406 Fructose-2,6-bisphosphatase; phosphoglycerate mutase 4718989 17445018 AFR_21735 Actinoplanes friuliensis DSM 7358 phosphoglycerate mutase YP_008735670.1 4718429 D 1246995 CDS YP_008735671.1 556567246 17445019 4719269..4719862 1 NC_022657.1 hypothetical protein 4719862 17445019 AFR_21740 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735671.1 4719269 D 1246995 CDS YP_008735672.1 556567247 17445020 complement(4719859..4720887) 1 NC_022657.1 COG0510 Predicted choline kinase involved in LPS biosynthesis; aminoglycoside phosphotransferase 4720887 17445020 AFR_21745 Actinoplanes friuliensis DSM 7358 aminoglycoside phosphotransferase YP_008735672.1 4719859 R 1246995 CDS YP_008735673.1 556567248 17445021 4720962..4721549 1 NC_022657.1 COG0640 Predicted transcriptional regulators; hypothetical protein 4721549 17445021 AFR_21750 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735673.1 4720962 D 1246995 CDS YP_008735674.1 556567249 17445022 4721553..4722260 1 NC_022657.1 hypothetical protein 4722260 17445022 AFR_21755 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735674.1 4721553 D 1246995 CDS YP_008735675.1 556567250 17445023 4722273..4723067 1 NC_022657.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); hydrolase 4723067 17445023 AFR_21760 Actinoplanes friuliensis DSM 7358 hydrolase YP_008735675.1 4722273 D 1246995 CDS YP_008735676.1 556567251 17445024 4723099..4725837 1 NC_022657.1 COG0642 Signal transduction histidine kinase; putative multi-sensor signal transduction histidine kinase 4725837 17445024 AFR_21765 Actinoplanes friuliensis DSM 7358 putative multi-sensor signal transduction histidine kinase YP_008735676.1 4723099 D 1246995 CDS YP_008735677.1 556567252 17445025 4725901..4727130 1 NC_022657.1 hypothetical protein 4727130 17445025 AFR_21770 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735677.1 4725901 D 1246995 CDS YP_008735678.1 556567253 17445026 4727341..4727679 1 NC_022657.1 hypothetical protein 4727679 17445026 AFR_21775 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735678.1 4727341 D 1246995 CDS YP_008735679.1 556567254 17445027 complement(4727748..4728278) 1 NC_022657.1 COG3030 Protein affecting phage T7 exclusion by the F plasmid; hypothetical protein 4728278 17445027 AFR_21780 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735679.1 4727748 R 1246995 CDS YP_008735680.1 556567255 17445028 complement(4728334..4729143) 1 NC_022657.1 COG0463 Glycosyltransferases involved in cell wall biogenesis; dolichol-phosphate mannosyltransferase 4729143 17445028 AFR_21785 Actinoplanes friuliensis DSM 7358 dolichol-phosphate mannosyltransferase YP_008735680.1 4728334 R 1246995 CDS YP_008735681.1 556567256 17445029 complement(4729162..4730676) 1 NC_022657.1 COG0815 Apolipoprotein N-acyltransferase; apolipoprotein N-acyltransferase 4730676 17445029 AFR_21790 Actinoplanes friuliensis DSM 7358 apolipoprotein N-acyltransferase YP_008735681.1 4729162 R 1246995 CDS YP_008735682.1 556567257 17445030 complement(4731231..4732478) 1 NC_022657.1 hypothetical protein 4732478 17445030 AFR_21795 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735682.1 4731231 R 1246995 CDS YP_008735683.1 556567258 17445031 complement(4732493..4732858) 1 NC_022657.1 COG1607 Acyl-CoA hydrolase; acyl-CoA hydrolase 4732858 17445031 AFR_21800 Actinoplanes friuliensis DSM 7358 acyl-CoA hydrolase YP_008735683.1 4732493 R 1246995 CDS YP_008735684.1 556567259 17445032 complement(4732855..4733589) 1 NC_022657.1 COG5012 Predicted cobalamin binding protein; putative lysine 5,6-aminomutase beta subunit 4733589 17445032 AFR_21805 Actinoplanes friuliensis DSM 7358 putative lysine 5,6-aminomutase beta subunit YP_008735684.1 4732855 R 1246995 CDS YP_008735685.1 556567260 17445033 complement(4733654..4735216) 1 NC_022657.1 beta-lysine 5,6-aminomutase 4735216 17445033 AFR_21810 Actinoplanes friuliensis DSM 7358 beta-lysine 5,6-aminomutase YP_008735685.1 4733654 R 1246995 CDS YP_008735686.1 556567261 17445034 complement(4735216..4736742) 1 NC_022657.1 COG1574 Predicted metal-dependent hydrolase with the TIM-barrel fold; putative amidohydrolase 4736742 17445034 AFR_21815 Actinoplanes friuliensis DSM 7358 putative amidohydrolase YP_008735686.1 4735216 R 1246995 CDS YP_008735687.1 556567262 17445035 complement(4736763..4737821) 1 NC_022657.1 L-erythro-3,5-diaminohexanoate dehydrogenase 4737821 17445035 AFR_21820 Actinoplanes friuliensis DSM 7358 L-erythro-3,5-diaminohexanoate dehydrogenase YP_008735687.1 4736763 R 1246995 CDS YP_008735688.1 556567263 17445036 4737953..4739329 1 NC_022657.1 COG1509 Lysine 2,3-aminomutase; lysine 2,3-aminomutase 4739329 17445036 AFR_21825 Actinoplanes friuliensis DSM 7358 lysine 2,3-aminomutase YP_008735688.1 4737953 D 1246995 CDS YP_008735689.1 556567264 17445037 complement(4739387..4739578) 1 NC_022657.1 hypothetical protein 4739578 17445037 AFR_21830 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735689.1 4739387 R 1246995 CDS YP_008735690.1 556567265 17445038 4739729..4740445 1 NC_022657.1 COG0500 SAM-dependent methyltransferases; putative methyltransferase 4740445 17445038 AFR_21835 Actinoplanes friuliensis DSM 7358 putative methyltransferase YP_008735690.1 4739729 D 1246995 CDS YP_008735691.1 556567266 17445039 complement(4740431..4741180) 1 NC_022657.1 COG0510 Predicted choline kinase involved in LPS biosynthesis; aminoglycoside phosphotransferase 4741180 17445039 AFR_21840 Actinoplanes friuliensis DSM 7358 aminoglycoside phosphotransferase YP_008735691.1 4740431 R 1246995 CDS YP_008735692.1 556567267 17445040 4741389..4742066 1 NC_022657.1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; winged helix family two component transcriptional regulator 4742066 17445040 AFR_21845 Actinoplanes friuliensis DSM 7358 winged helix family two component transcriptional regulator YP_008735692.1 4741389 D 1246995 CDS YP_008735693.1 556567268 17445041 4742110..4742955 1 NC_022657.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); alpha/beta hydrolase fold protein 4742955 17445041 AFR_21850 Actinoplanes friuliensis DSM 7358 alpha/beta hydrolase fold protein YP_008735693.1 4742110 D 1246995 CDS YP_008735694.1 556567269 17445042 complement(4744327..4744815) 1 NC_022657.1 COG1522 Transcriptional regulators; putative AsnC-family transcriptional regulator 4744815 17445042 AFR_21855 Actinoplanes friuliensis DSM 7358 putative AsnC-family transcriptional regulator YP_008735694.1 4744327 R 1246995 CDS YP_008735695.1 556567270 17445043 complement(4744827..4745969) 1 NC_022657.1 COG1960 Acyl-CoA dehydrogenases; acyl-CoA dehydrogenase 4745969 17445043 AFR_21860 Actinoplanes friuliensis DSM 7358 acyl-CoA dehydrogenase YP_008735695.1 4744827 R 1246995 CDS YP_008735696.1 556567271 17445044 4746053..4746964 1 NC_022657.1 COG0258 5'-3' exonuclease (including N-terminal domain of PolI); 5'-3' exonuclease 4746964 17445044 AFR_21865 Actinoplanes friuliensis DSM 7358 5'-3' exonuclease YP_008735696.1 4746053 D 1246995 CDS YP_008735697.1 556567272 17445045 complement(4747195..4749912) 1 NC_022657.1 COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain; Signaling protein ykoW 4749912 17445045 AFR_21870 Actinoplanes friuliensis DSM 7358 Signaling protein ykoW YP_008735697.1 4747195 R 1246995 CDS YP_008735698.1 556567273 17445046 4750039..4750449 1 NC_022657.1 COG3801 Uncharacterized protein conserved in bacteria; hypothetical protein 4750449 17445046 AFR_21875 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735698.1 4750039 D 1246995 CDS YP_008735699.1 556567274 17445047 4750446..4751009 1 NC_022657.1 COG1309 Transcriptional regulator; TetR family transcriptional regulator 4751009 17445047 AFR_21880 Actinoplanes friuliensis DSM 7358 TetR family transcriptional regulator YP_008735699.1 4750446 D 1246995 CDS YP_008735700.1 556567275 17445048 complement(4751006..4751671) 1 NC_022657.1 COG0400 Predicted esterase; phospholipase/carboxylesterase 4751671 17445048 AFR_21885 Actinoplanes friuliensis DSM 7358 phospholipase/carboxylesterase YP_008735700.1 4751006 R 1246995 CDS YP_008735701.1 556567276 17445049 complement(4751623..4752261) 1 NC_022657.1 COG2085 Predicted dinucleotide-binding enzymes; coenzyme F420-dependent NADP oxidoreductase 4752261 17445049 AFR_21890 Actinoplanes friuliensis DSM 7358 coenzyme F420-dependent NADP oxidoreductase YP_008735701.1 4751623 R 1246995 CDS YP_008735702.1 556567277 17445050 4752423..4754240 1 NC_022657.1 COG2199 FOG: GGDEF domain; hypothetical protein 4754240 17445050 AFR_21895 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735702.1 4752423 D 1246995 CDS YP_008735703.1 556567278 17445051 complement(4754247..4754720) 1 NC_022657.1 COG5500 Predicted integral membrane protein; hypothetical protein 4754720 17445051 AFR_21900 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735703.1 4754247 R 1246995 CDS YP_008735704.1 556567279 17445052 complement(4754790..4756490) 1 NC_022657.1 COG1112 Superfamily I DNA and RNA helicases and helicase subunits; hypothetical protein 4756490 17445052 AFR_21905 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735704.1 4754790 R 1246995 CDS YP_008735705.1 556567280 17445053 4756731..4757960 1 NC_022657.1 COG2355 Zn-dependent dipeptidase, microsomal dipeptidase homolog; membrane dipeptidase 4757960 17445053 AFR_21910 Actinoplanes friuliensis DSM 7358 membrane dipeptidase YP_008735705.1 4756731 D 1246995 CDS YP_008735706.1 556567281 17445054 4757997..4758650 1 NC_022657.1 hypothetical protein 4758650 17445054 AFR_21915 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735706.1 4757997 D 1246995 CDS YP_008735707.1 556567282 17445055 4758720..4759499 1 NC_022657.1 hypothetical protein 4759499 17445055 AFR_21920 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735707.1 4758720 D 1246995 CDS YP_008735708.1 556567283 17445056 complement(4759506..4760165) 1 NC_022657.1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; putative two-component system response regulator 4760165 17445056 AFR_21925 Actinoplanes friuliensis DSM 7358 putative two-component system response regulator YP_008735708.1 4759506 R 1246995 CDS YP_008735709.1 556567284 17445057 complement(4760162..4761442) 1 NC_022657.1 COG4585 Signal transduction histidine kinase; putative two-component system sensor kinase 4761442 17445057 AFR_21930 Actinoplanes friuliensis DSM 7358 putative two-component system sensor kinase YP_008735709.1 4760162 R 1246995 CDS YP_008735710.1 556567285 17445058 4761574..4762473 1 NC_022657.1 COG1131 ABC-type multidrug transport system, ATPase component; ABC transporter-like protein 4762473 17445058 AFR_21935 Actinoplanes friuliensis DSM 7358 ABC transporter-like protein YP_008735710.1 4761574 D 1246995 CDS YP_008735711.1 556567286 17445059 4762470..4763270 1 NC_022657.1 hypothetical protein 4763270 17445059 AFR_21940 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735711.1 4762470 D 1246995 CDS YP_008735712.1 556567287 17445060 4763308..4763574 1 NC_022657.1 hypothetical protein 4763574 17445060 AFR_21945 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735712.1 4763308 D 1246995 CDS YP_008735713.1 556567288 17445061 4763662..4765752 1 NC_022657.1 COG4412 Uncharacterized protein conserved in bacteria; hypothetical protein 4765752 17445061 AFR_21950 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735713.1 4763662 D 1246995 CDS YP_008735714.1 556567289 17445062 complement(4765728..4766432) 1 NC_022657.1 COG1878 Predicted metal-dependent hydrolase; cyclase family protein 4766432 17445062 AFR_21955 Actinoplanes friuliensis DSM 7358 cyclase family protein YP_008735714.1 4765728 R 1246995 CDS YP_008735715.1 556567290 17445063 4766533..4767111 1 NC_022657.1 COG0572 Uridine kinase; hypothetical protein 4767111 17445063 AFR_21960 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735715.1 4766533 D 1246995 CDS YP_008735716.1 556567291 17445064 4767330..4767815 1 NC_022657.1 hypothetical protein 4767815 17445064 AFR_21965 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735716.1 4767330 D 1246995 CDS YP_008735717.1 556567292 17445065 4767862..4768458 1 NC_022657.1 hypothetical protein 4768458 17445065 AFR_21970 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735717.1 4767862 D 1246995 CDS YP_008735718.1 556567293 17445066 4768455..4770791 1 NC_022657.1 hypothetical protein 4770791 17445066 AFR_21975 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735718.1 4768455 D 1246995 CDS YP_008735719.1 556567294 17445067 complement(4770831..4772528) 1 NC_022657.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); TAP domain-containing protein 4772528 17445067 AFR_21980 Actinoplanes friuliensis DSM 7358 TAP domain-containing protein YP_008735719.1 4770831 R 1246995 CDS YP_008735720.1 556567295 17445068 4772758..4773642 1 NC_022657.1 Ricin 4773642 17445068 AFR_21985 Actinoplanes friuliensis DSM 7358 Ricin YP_008735720.1 4772758 D 1246995 CDS YP_008735721.1 556567296 17445069 4773719..4774168 1 NC_022657.1 hypothetical protein 4774168 17445069 AFR_21990 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735721.1 4773719 D 1246995 CDS YP_008735722.1 556567297 17445070 complement(4774614..4775531) 1 NC_022657.1 COG3546 Mn-containing catalase; putative manganese-containing catalase 4775531 17445070 AFR_21995 Actinoplanes friuliensis DSM 7358 putative manganese-containing catalase YP_008735722.1 4774614 R 1246995 CDS YP_008735723.1 556567298 17445071 4775660..4776142 1 NC_022657.1 COG4329 Predicted membrane protein; hypothetical protein 4776142 17445071 AFR_22000 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735723.1 4775660 D 1246995 CDS YP_008735724.1 556567299 17445072 4776139..4776918 1 NC_022657.1 COG3336 Predicted membrane protein; hypothetical protein 4776918 17445072 AFR_22005 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735724.1 4776139 D 1246995 CDS YP_008735725.1 556567300 17445073 complement(4776828..4776965) 1 NC_022657.1 COG1982 Arginine/lysine/ornithine decarboxylases; lysine decarboxylase 4776965 17445073 AFR_22010 Actinoplanes friuliensis DSM 7358 lysine decarboxylase YP_008735725.1 4776828 R 1246995 CDS YP_008735726.1 556567301 17445074 4777233..4778489 1 NC_022657.1 COG1914 Mn2+ and Fe2+ transporters of the NRAMP family; putative metal ion transport protein 4778489 17445074 AFR_22015 Actinoplanes friuliensis DSM 7358 putative metal ion transport protein YP_008735726.1 4777233 D 1246995 CDS YP_008735727.1 556567302 17445075 complement(4778529..4779140) 1 NC_022657.1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; two component LuxR family transcriptional regulator 4779140 17445075 AFR_22020 Actinoplanes friuliensis DSM 7358 two component LuxR family transcriptional regulator YP_008735727.1 4778529 R 1246995 CDS YP_008735728.1 556567303 17445076 4779126..4779848 1 NC_022657.1 COG0642 Signal transduction histidine kinase; putative two-component system sensor kinase 4779848 17445076 AFR_22025 Actinoplanes friuliensis DSM 7358 putative two-component system sensor kinase YP_008735728.1 4779126 D 1246995 CDS YP_008735729.1 556567304 17445077 4779936..4780118 1 NC_022657.1 hypothetical protein 4780118 17445077 AFR_22030 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735729.1 4779936 D 1246995 CDS YP_008735730.1 556567305 17445078 complement(4780107..4780781) 1 NC_022657.1 COG0463 Glycosyltransferases involved in cell wall biogenesis; glycosyltransferase 4780781 17445078 AFR_22035 Actinoplanes friuliensis DSM 7358 glycosyltransferase YP_008735730.1 4780107 R 1246995 CDS YP_008735731.1 556567306 17445079 complement(4780775..4781383) 1 NC_022657.1 COG0500 SAM-dependent methyltransferases; Methyltransferase type 12 4781383 17445079 AFR_22040 Actinoplanes friuliensis DSM 7358 Methyltransferase type 12 YP_008735731.1 4780775 R 1246995 CDS YP_008735732.1 556567307 17445080 complement(4781380..4782102) 1 NC_022657.1 hypothetical protein 4782102 17445080 AFR_22045 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735732.1 4781380 R 1246995 CDS YP_008735733.1 556567308 17445081 complement(4782096..4783022) 1 NC_022657.1 COG1960 Acyl-CoA dehydrogenases; acyl-CoA dehydrogenase 4783022 17445081 AFR_22050 Actinoplanes friuliensis DSM 7358 acyl-CoA dehydrogenase YP_008735733.1 4782096 R 1246995 CDS YP_008735734.1 556567309 17445082 4783110..4783610 1 NC_022657.1 hypothetical protein 4783610 17445082 AFR_22055 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735734.1 4783110 D 1246995 CDS YP_008735735.1 556567310 17445083 4783648..4784514 1 NC_022657.1 COG3595 Uncharacterized conserved protein; hypothetical protein 4784514 17445083 AFR_22060 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735735.1 4783648 D 1246995 CDS YP_008735736.1 556567311 17445084 4784514..4785434 1 NC_022657.1 COG1131 ABC-type multidrug transport system, ATPase component; ABC transporter ATP-binding protein 4785434 17445084 AFR_22065 Actinoplanes friuliensis DSM 7358 ABC transporter ATP-binding protein YP_008735736.1 4784514 D 1246995 CDS YP_008735737.1 556567312 17445085 4785431..4786207 1 NC_022657.1 COG0842 ABC-type multidrug transport system, permease component; multidrug ABC transporter permease 4786207 17445085 AFR_22070 Actinoplanes friuliensis DSM 7358 multidrug ABC transporter permease YP_008735737.1 4785431 D 1246995 CDS YP_008735738.1 556567313 17445086 complement(4786259..4787497) 1 NC_022657.1 COG2312 Erythromycin esterase homolog; EreC 4787497 17445086 AFR_22075 Actinoplanes friuliensis DSM 7358 EreC YP_008735738.1 4786259 R 1246995 CDS YP_008735739.1 556567314 17445087 complement(4787721..4788644) 1 NC_022657.1 COG1396 Predicted transcriptional regulators; MmyB family DNA-binding protein 4788644 17445087 AFR_22080 Actinoplanes friuliensis DSM 7358 MmyB family DNA-binding protein YP_008735739.1 4787721 R 1246995 CDS YP_008735740.1 556567315 17445088 4788855..4789841 1 NC_022657.1 COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases); aldo/keto reductase 4789841 17445088 AFR_22085 Actinoplanes friuliensis DSM 7358 aldo/keto reductase YP_008735740.1 4788855 D 1246995 CDS YP_008735741.1 556567316 17445089 4789872..4790684 1 NC_022657.1 COG2220 Predicted Zn-dependent hydrolases of the beta-lactamase fold; hypothetical protein 4790684 17445089 AFR_22090 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735741.1 4789872 D 1246995 CDS YP_008735742.1 556567317 17445090 4790681..4792297 1 NC_022657.1 COG0477 Permeases of the major facilitator superfamily; ykuC-like MFS-type transporter 4792297 17445090 AFR_22095 Actinoplanes friuliensis DSM 7358 ykuC-like MFS-type transporter YP_008735742.1 4790681 D 1246995 CDS YP_008735743.1 556567318 17445091 complement(4792523..4794706) 1 NC_022657.1 Ricin 4794706 17445091 AFR_22100 Actinoplanes friuliensis DSM 7358 Ricin YP_008735743.1 4792523 R 1246995 CDS YP_008735744.1 556567319 17445092 complement(4794737..4795927) 1 NC_022657.1 hypothetical protein 4795927 17445092 AFR_22105 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735744.1 4794737 R 1246995 CDS YP_008735745.1 556567320 17445093 complement(4796141..4796473) 1 NC_022657.1 YCII-like protein 4796473 17445093 AFR_22110 Actinoplanes friuliensis DSM 7358 YCII-like protein YP_008735745.1 4796141 R 1246995 CDS YP_008735746.1 556567321 17445094 4796519..4796926 1 NC_022657.1 glyoxalase/bleomycin resistance protein/dioxygenase 4796926 17445094 AFR_22115 Actinoplanes friuliensis DSM 7358 glyoxalase/bleomycin resistance protein/dioxygenase YP_008735746.1 4796519 D 1246995 CDS YP_008735747.1 556567322 17445095 4796904..4797764 1 NC_022657.1 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; acetyltransferase 4797764 17445095 AFR_22120 Actinoplanes friuliensis DSM 7358 acetyltransferase YP_008735747.1 4796904 D 1246995 CDS YP_008735748.1 556567323 17445096 complement(4797765..4798721) 1 NC_022657.1 hypothetical protein 4798721 17445096 AFR_22125 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735748.1 4797765 R 1246995 CDS YP_008735749.1 556567324 17445097 4798791..4799576 1 NC_022657.1 hypothetical protein 4799576 17445097 AFR_22130 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735749.1 4798791 D 1246995 CDS YP_008735750.1 556567325 17445098 complement(4799579..4800157) 1 NC_022657.1 COG1309 Transcriptional regulator; HTH-type transcriptional regulator betI 4800157 17445098 AFR_22135 Actinoplanes friuliensis DSM 7358 HTH-type transcriptional regulator betI YP_008735750.1 4799579 R 1246995 CDS YP_008735751.1 556567326 17445099 4800222..4801001 1 NC_022657.1 COG0300 Short-chain dehydrogenases of various substrate specificities; oxidoreductase 4801001 17445099 AFR_22140 Actinoplanes friuliensis DSM 7358 oxidoreductase YP_008735751.1 4800222 D 1246995 CDS YP_008735752.1 556567327 17445100 4801038..4801607 1 NC_022657.1 COG1309 Transcriptional regulator; putative transcriptional regulator, TetR family protein 4801607 17445100 AFR_22145 Actinoplanes friuliensis DSM 7358 putative transcriptional regulator, TetR family protein YP_008735752.1 4801038 D 1246995 CDS YP_008735753.1 556567328 17445101 4801597..4802259 1 NC_022657.1 COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase; phospholipid/glycerol acyltransferase 4802259 17445101 AFR_22150 Actinoplanes friuliensis DSM 7358 phospholipid/glycerol acyltransferase YP_008735753.1 4801597 D 1246995 CDS YP_008735754.1 556567329 17445102 complement(4802320..4803276) 1 NC_022657.1 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases; putative luciferase-like monooxygenase 4803276 17445102 AFR_22155 Actinoplanes friuliensis DSM 7358 putative luciferase-like monooxygenase YP_008735754.1 4802320 R 1246995 CDS YP_008735755.1 556567330 17445103 4803335..4804243 1 NC_022657.1 COG1957 Inosine-uridine nucleoside N-ribohydrolase; purine nucleosidase 4804243 17445103 AFR_22160 Actinoplanes friuliensis DSM 7358 purine nucleosidase YP_008735755.1 4803335 D 1246995 CDS YP_008735756.1 556567331 17445104 4804288..4804860 1 NC_022657.1 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; RNA polymerase ECF-subfamily sigma factor 4804860 17445104 AFR_22165 Actinoplanes friuliensis DSM 7358 RNA polymerase ECF-subfamily sigma factor YP_008735756.1 4804288 D 1246995 CDS YP_008735757.1 556567332 17445105 4804857..4805834 1 NC_022657.1 hypothetical protein 4805834 17445105 AFR_22170 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735757.1 4804857 D 1246995 CDS YP_008735758.1 556567333 17445106 complement(4805838..4806479) 1 NC_022657.1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; putative two-component system response regulator 4806479 17445106 AFR_22175 Actinoplanes friuliensis DSM 7358 putative two-component system response regulator YP_008735758.1 4805838 R 1246995 CDS YP_008735759.1 556567334 17445107 4806903..4807235 1 NC_022657.1 hypothetical protein 4807235 17445107 AFR_22180 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735759.1 4806903 D 1246995 CDS YP_008735760.1 556567335 17445108 4807235..4807759 1 NC_022657.1 COG3576 Predicted flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase; pyridoxamine 5'-phosphate oxidase-related FMN- binding protein 4807759 17445108 AFR_22185 Actinoplanes friuliensis DSM 7358 pyridoxamine 5'-phosphate oxidase-related FMN- binding protein YP_008735760.1 4807235 D 1246995 CDS YP_008735761.1 556567336 17445109 4807826..4809490 1 NC_022657.1 COG3605 Signal transduction protein containing GAF and PtsI domains; GAF sensor signal transduction histidine kinase 4809490 17445109 AFR_22190 Actinoplanes friuliensis DSM 7358 GAF sensor signal transduction histidine kinase YP_008735761.1 4807826 D 1246995 CDS YP_008735762.1 556567337 17445110 4809564..4810526 1 NC_022657.1 nitroreductase 4810526 17445110 AFR_22195 Actinoplanes friuliensis DSM 7358 nitroreductase YP_008735762.1 4809564 D 1246995 CDS YP_008735763.1 556567338 17445111 4810526..4811470 1 NC_022657.1 hypothetical protein 4811470 17445111 AFR_22200 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735763.1 4810526 D 1246995 CDS YP_008735764.1 556567339 17445112 4811577..4812161 1 NC_022657.1 doxx family protein 4812161 17445112 AFR_22205 Actinoplanes friuliensis DSM 7358 doxx family protein YP_008735764.1 4811577 D 1246995 CDS YP_008735765.1 556567340 17445113 complement(4812215..4812688) 1 NC_022657.1 COG1881 Phospholipid-binding protein; hypothetical protein 4812688 17445113 AFR_22210 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735765.1 4812215 R 1246995 CDS YP_008735766.1 556567341 17445114 4812761..4813177 1 NC_022657.1 COG1846 Transcriptional regulators; putative MarR-family transcriptional regulator 4813177 17445114 AFR_22215 Actinoplanes friuliensis DSM 7358 putative MarR-family transcriptional regulator YP_008735766.1 4812761 D 1246995 CDS YP_008735767.1 556567342 17445115 4813242..4813874 1 NC_022657.1 COG0515 Serine/threonine protein kinase; protein kinase 4813874 17445115 AFR_22220 Actinoplanes friuliensis DSM 7358 protein kinase YP_008735767.1 4813242 D 1246995 CDS YP_008735768.1 556567343 17445116 4813878..4814318 1 NC_022657.1 COG3832 Uncharacterized conserved protein; hypothetical protein 4814318 17445116 AFR_22225 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735768.1 4813878 D 1246995 CDS YP_008735769.1 556567344 17445117 complement(4814343..4815416) 1 NC_022657.1 COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases; acetylornithine deacetylase/Succinyl- diaminopimelate desuccinylase-like protein 4815416 17445117 AFR_22230 Actinoplanes friuliensis DSM 7358 acetylornithine deacetylase/Succinyl- diaminopimelate desuccinylase-like protein YP_008735769.1 4814343 R 1246995 CDS YP_008735770.1 556567345 17445118 complement(4815426..4816295) 1 NC_022657.1 COG0583 Transcriptional regulator; LysR family transcriptional regulator 4816295 17445118 AFR_22235 Actinoplanes friuliensis DSM 7358 LysR family transcriptional regulator YP_008735770.1 4815426 R 1246995 CDS YP_008735771.1 556567346 17445119 4816571..4817299 1 NC_022657.1 COG2267 Lysophospholipase; hypothetical protein 4817299 17445119 AFR_22240 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735771.1 4816571 D 1246995 CDS YP_008735772.1 556567347 17445120 4817296..4819140 1 NC_022657.1 COG1893 Ketopantoate reductase; ketopantoate reductase ApbA/PanE 4819140 17445120 AFR_22245 Actinoplanes friuliensis DSM 7358 ketopantoate reductase ApbA/PanE YP_008735772.1 4817296 D 1246995 CDS YP_008735773.1 556567348 17445121 4819137..4820003 1 NC_022657.1 COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component; binding-protein-dependent transport systems inner membrane component 4820003 17445121 AFR_22250 Actinoplanes friuliensis DSM 7358 binding-protein-dependent transport systems inner membrane component YP_008735773.1 4819137 D 1246995 CDS YP_008735774.1 556567349 17445122 4820003..4820692 1 NC_022657.1 COG1116 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component; ABC transporter ATP-binding protein 4820692 17445122 AFR_22255 Actinoplanes friuliensis DSM 7358 ABC transporter ATP-binding protein YP_008735774.1 4820003 D 1246995 CDS YP_008735775.1 556567350 17445123 4820689..4821645 1 NC_022657.1 COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components; nitrate/sulfonate/bicarbonate family ABC transporter periplasmic ligand binding protein 4821645 17445123 AFR_22260 Actinoplanes friuliensis DSM 7358 nitrate/sulfonate/bicarbonate family ABC transporter periplasmic ligand binding protein YP_008735775.1 4820689 D 1246995 CDS YP_008735776.1 556567351 17445124 4821655..4822740 1 NC_022657.1 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases; alkanesulfonate monooxygenase 4822740 17445124 AFR_22265 Actinoplanes friuliensis DSM 7358 alkanesulfonate monooxygenase YP_008735776.1 4821655 D 1246995 CDS YP_008735777.1 556567352 17445125 4822737..4823735 1 NC_022657.1 COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components; nitrate/sulfonate/bicarbonate ABC transporter periplasmic protein 4823735 17445125 AFR_22270 Actinoplanes friuliensis DSM 7358 nitrate/sulfonate/bicarbonate ABC transporter periplasmic protein YP_008735777.1 4822737 D 1246995 CDS YP_008735778.1 556567353 17445126 4823732..4824847 1 NC_022657.1 COG1960 Acyl-CoA dehydrogenases; acyl-CoA dehydrogenase-related protein 4824847 17445126 AFR_22275 Actinoplanes friuliensis DSM 7358 acyl-CoA dehydrogenase-related protein YP_008735778.1 4823732 D 1246995 CDS YP_008735779.1 556567354 17445127 4824844..4826169 1 NC_022657.1 COG0277 FAD/FMN-containing dehydrogenases; D-lactate dehydrogenase 4826169 17445127 AFR_22280 Actinoplanes friuliensis DSM 7358 D-lactate dehydrogenase YP_008735779.1 4824844 D 1246995 CDS YP_008735780.1 556567355 17445128 4826319..4827251 1 NC_022657.1 COG3839 ABC-type sugar transport systems, ATPase components; putative GCN5-related N-acetyltransferase 4827251 17445128 AFR_22285 Actinoplanes friuliensis DSM 7358 putative GCN5-related N-acetyltransferase YP_008735780.1 4826319 D 1246995 CDS YP_008735781.1 556567356 17445129 complement(4827289..4827882) 1 NC_022657.1 COG1309 Transcriptional regulator; TetR family transcriptional regulator 4827882 17445129 AFR_22290 Actinoplanes friuliensis DSM 7358 TetR family transcriptional regulator YP_008735781.1 4827289 R 1246995 CDS YP_008735782.1 556567357 17445130 4827949..4828356 1 NC_022657.1 COG0251 Putative translation initiation inhibitor, yjgF family; endoribonuclease L-PSP 4828356 17445130 AFR_22295 Actinoplanes friuliensis DSM 7358 endoribonuclease L-PSP YP_008735782.1 4827949 D 1246995 CDS YP_008735783.1 556567358 17445131 complement(4828346..4829494) 1 NC_022657.1 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases; Alkanesulfonate monooxygenase 4829494 17445131 AFR_22300 Actinoplanes friuliensis DSM 7358 Alkanesulfonate monooxygenase YP_008735783.1 4828346 R 1246995 CDS YP_008735784.1 556567359 17445132 4829542..4830489 1 NC_022657.1 COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components; aliphatic sulfonates family ABC transporter, periplasmic ligand-binding protein 4830489 17445132 AFR_22305 Actinoplanes friuliensis DSM 7358 aliphatic sulfonates family ABC transporter, periplasmic ligand-binding protein YP_008735784.1 4829542 D 1246995 CDS YP_008735785.1 556567360 17445133 4830486..4831304 1 NC_022657.1 COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component; binding-protein-dependent transport systems inner membrane component 4831304 17445133 AFR_22310 Actinoplanes friuliensis DSM 7358 binding-protein-dependent transport systems inner membrane component YP_008735785.1 4830486 D 1246995 CDS YP_008735786.1 556567361 17445134 4831277..4832008 1 NC_022657.1 COG1116 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component; ABC transporter-like protein 4832008 17445134 AFR_22315 Actinoplanes friuliensis DSM 7358 ABC transporter-like protein YP_008735786.1 4831277 D 1246995 CDS YP_008735787.1 556567362 17445135 complement(4831994..4832428) 1 NC_022657.1 COG4682 Predicted membrane protein; Inner membrane protein yiaA 4832428 17445135 AFR_22320 Actinoplanes friuliensis DSM 7358 Inner membrane protein yiaA YP_008735787.1 4831994 R 1246995 CDS YP_008735788.1 556567363 17445136 complement(4832492..4833019) 1 NC_022657.1 hypothetical protein 4833019 17445136 AFR_22325 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735788.1 4832492 R 1246995 CDS YP_008735789.1 556567364 17445137 complement(4833329..4833673) 1 NC_022657.1 COG1146 Ferredoxin; 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein 4833673 17445137 AFR_22330 Actinoplanes friuliensis DSM 7358 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein YP_008735789.1 4833329 R 1246995 CDS YP_008735790.1 556567365 17445138 complement(4833670..4835226) 1 NC_022657.1 FAD-dependent pyridine nucleotide-disulfide oxidoreductase 4835226 17445138 AFR_22335 Actinoplanes friuliensis DSM 7358 FAD-dependent pyridine nucleotide-disulfide oxidoreductase YP_008735790.1 4833670 R 1246995 CDS YP_008735791.1 556567366 17445139 complement(4835227..4836330) 1 NC_022657.1 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases; hypothetical protein 4836330 17445139 AFR_22340 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735791.1 4835227 R 1246995 CDS YP_008735792.1 556567367 17445140 complement(4836333..4837364) 1 NC_022657.1 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases; luciferase-like monooxygenase 4837364 17445140 AFR_22345 Actinoplanes friuliensis DSM 7358 luciferase-like monooxygenase YP_008735792.1 4836333 R 1246995 CDS YP_008735793.1 556567368 17445141 complement(4837361..4838668) 1 NC_022657.1 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases; putative FMNH2-utilizing oxygenase 4838668 17445141 AFR_22350 Actinoplanes friuliensis DSM 7358 putative FMNH2-utilizing oxygenase YP_008735793.1 4837361 R 1246995 CDS YP_008735794.1 556567369 17445142 complement(4838661..4839797) 1 NC_022657.1 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases; xenobiotic compound DszA family monooxygenase 4839797 17445142 AFR_22355 Actinoplanes friuliensis DSM 7358 xenobiotic compound DszA family monooxygenase YP_008735794.1 4838661 R 1246995 CDS YP_008735795.1 556567370 17445143 complement(4839794..4841350) 1 NC_022657.1 COG4172 ABC-type uncharacterized transport system, duplicated ATPase component; Glutathione import ATP-binding protein gsiA 4841350 17445143 AFR_22360 Actinoplanes friuliensis DSM 7358 Glutathione import ATP-binding protein gsiA YP_008735795.1 4839794 R 1246995 CDS YP_008735796.1 556567371 17445144 complement(4841347..4842201) 1 NC_022657.1 COG1173 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components; peptide/nickel transport system permease protein 4842201 17445144 AFR_22365 Actinoplanes friuliensis DSM 7358 peptide/nickel transport system permease protein YP_008735796.1 4841347 R 1246995 CDS YP_008735797.1 556567372 17445145 complement(4842205..4843116) 1 NC_022657.1 COG0601 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components; putative D,D-dipeptide transport system permease protein ddpB 4843116 17445145 AFR_22370 Actinoplanes friuliensis DSM 7358 putative D,D-dipeptide transport system permease protein ddpB YP_008735797.1 4842205 R 1246995 CDS YP_008735798.1 556567373 17445146 complement(4843113..4844714) 1 NC_022657.1 COG0747 ABC-type dipeptide transport system, periplasmic component; peptide/nickel transport system substrate-binding protein 4844714 17445146 AFR_22375 Actinoplanes friuliensis DSM 7358 peptide/nickel transport system substrate-binding protein YP_008735798.1 4843113 R 1246995 CDS YP_008735799.1 556567374 17445147 4844947..4845744 1 NC_022657.1 COG2334 Putative homoserine kinase type II (protein kinase fold); aminoglycoside phosphotransferase 4845744 17445147 AFR_22380 Actinoplanes friuliensis DSM 7358 aminoglycoside phosphotransferase YP_008735799.1 4844947 D 1246995 CDS YP_008735800.1 556567375 17445148 4845815..4846564 1 NC_022657.1 COG1136 ABC-type antimicrobial peptide transport system, ATPase component; putative ABC transporter ATP-binding protein 4846564 17445148 AFR_22385 Actinoplanes friuliensis DSM 7358 putative ABC transporter ATP-binding protein YP_008735800.1 4845815 D 1246995 CDS YP_008735801.1 556567376 17445149 4846575..4848455 1 NC_022657.1 hypothetical protein 4848455 17445149 AFR_22390 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735801.1 4846575 D 1246995 CDS YP_008735802.1 556567377 17445150 complement(4848460..4849056) 1 NC_022657.1 COG4832 Uncharacterized conserved protein; hypothetical protein 4849056 17445150 AFR_22395 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735802.1 4848460 R 1246995 CDS YP_008735803.1 556567378 17445151 complement(4849064..4849471) 1 NC_022657.1 COG0589 Universal stress protein UspA and related nucleotide-binding proteins; hypothetical protein 4849471 17445151 AFR_22400 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735803.1 4849064 R 1246995 CDS YP_008735804.1 556567379 17445152 4849605..4850969 1 NC_022657.1 COG0531 Amino acid transporters; putative amino acid permease 4850969 17445152 AFR_22405 Actinoplanes friuliensis DSM 7358 putative amino acid permease YP_008735804.1 4849605 D 1246995 CDS YP_008735805.1 556567380 17445153 4851034..4851537 1 NC_022657.1 hypothetical protein 4851537 17445153 AFR_22410 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735805.1 4851034 D 1246995 CDS YP_008735806.1 556567381 17445154 complement(4851514..4852281) 1 NC_022657.1 COG0329 Dihydrodipicolinate synthase/N-acetylneuraminate lyase; dihydrodipicolinate synthase 4852281 17445154 AFR_22415 Actinoplanes friuliensis DSM 7358 dihydrodipicolinate synthase YP_008735806.1 4851514 R 1246995 CDS YP_008735807.1 556567382 17445155 complement(4852321..4853217) 1 NC_022657.1 COG0702 Predicted nucleoside-diphosphate-sugar epimerases; NmrA family protein 4853217 17445155 AFR_22420 Actinoplanes friuliensis DSM 7358 NmrA family protein YP_008735807.1 4852321 R 1246995 CDS YP_008735808.1 556567383 17445156 4853312..4853863 1 NC_022657.1 COG1309 Transcriptional regulator; regulatory protein TetR 4853863 17445156 AFR_22425 Actinoplanes friuliensis DSM 7358 regulatory protein TetR YP_008735808.1 4853312 D 1246995 CDS YP_008735809.1 556567384 17445157 complement(4853849..4856086) 1 NC_022657.1 COG1501 Alpha-glucosidases, family 31 of glycosyl hydrolases; alpha-glucosidase 4856086 17445157 AFR_22430 Actinoplanes friuliensis DSM 7358 alpha-glucosidase YP_008735809.1 4853849 R 1246995 CDS YP_008735810.1 556567385 17445158 complement(4856121..4856948) 1 NC_022657.1 COG0395 ABC-type sugar transport system, permease component; ABC transporter permease 4856948 17445158 AFR_22435 Actinoplanes friuliensis DSM 7358 ABC transporter permease YP_008735810.1 4856121 R 1246995 CDS YP_008735811.1 556567386 17445159 complement(4856951..4857817) 1 NC_022657.1 COG1175 ABC-type sugar transport systems, permease components; putative ABC transporter permease protein yurN 4857817 17445159 AFR_22440 Actinoplanes friuliensis DSM 7358 putative ABC transporter permease protein yurN YP_008735811.1 4856951 R 1246995 CDS YP_008735812.1 556567387 17445160 complement(4857850..4859142) 1 NC_022657.1 COG1653 ABC-type sugar transport system, periplasmic component; putative ABC transporter substrate-binding protein 4859142 17445160 AFR_22445 Actinoplanes friuliensis DSM 7358 putative ABC transporter substrate-binding protein YP_008735812.1 4857850 R 1246995 CDS YP_008735813.1 556567388 17445161 complement(4859270..4860385) 1 NC_022657.1 COG0457 FOG: TPR repeat; hypothetical protein 4860385 17445161 AFR_22450 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735813.1 4859270 R 1246995 CDS YP_008735814.1 556567389 17445162 complement(4860385..4860837) 1 NC_022657.1 hypothetical protein 4860837 17445162 AFR_22455 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735814.1 4860385 R 1246995 CDS YP_008735815.1 556567390 17445163 complement(4860894..4861901) 1 NC_022657.1 COG1609 Transcriptional regulators; LacI family transcriptional regulator 4861901 17445163 AFR_22460 Actinoplanes friuliensis DSM 7358 LacI family transcriptional regulator YP_008735815.1 4860894 R 1246995 CDS YP_008735816.1 556567391 17445164 complement(4861983..4862780) 1 NC_022657.1 COG0500 SAM-dependent methyltransferases; methyltransferase, S-adenosyl-L-methionine (SAM)-MTase protein 4862780 17445164 AFR_22465 Actinoplanes friuliensis DSM 7358 methyltransferase, S-adenosyl-L-methionine (SAM)-MTase protein YP_008735816.1 4861983 R 1246995 CDS YP_008735817.1 556567392 17445165 4862836..4863477 1 NC_022657.1 cellulose-binding family II protein 4863477 17445165 AFR_22470 Actinoplanes friuliensis DSM 7358 cellulose-binding family II protein YP_008735817.1 4862836 D 1246995 CDS YP_008735818.1 556567393 17445166 4863537..4865495 1 NC_022657.1 group 1 glycosyl transferase 4865495 17445166 AFR_22475 Actinoplanes friuliensis DSM 7358 group 1 glycosyl transferase YP_008735818.1 4863537 D 1246995 CDS YP_008735819.1 556567394 17445167 4865492..4866757 1 NC_022657.1 COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase; UDP-glucuronosyl/UDP-glucosyltransferase 4866757 17445167 AFR_22480 Actinoplanes friuliensis DSM 7358 UDP-glucuronosyl/UDP-glucosyltransferase YP_008735819.1 4865492 D 1246995 CDS YP_008735820.1 556567395 17445168 complement(4866750..4868012) 1 NC_022657.1 COG0673 Predicted dehydrogenases and related proteins; oxidoreductase domain-containing protein 4868012 17445168 AFR_22485 Actinoplanes friuliensis DSM 7358 oxidoreductase domain-containing protein YP_008735820.1 4866750 R 1246995 CDS YP_008735821.1 556567396 17445169 complement(4868014..4868865) 1 NC_022657.1 COG0191 Fructose/tagatose bisphosphate aldolase; tagatose-bisphosphate aldolase 4868865 17445169 AFR_22490 Actinoplanes friuliensis DSM 7358 tagatose-bisphosphate aldolase YP_008735821.1 4868014 R 1246995 CDS YP_008735822.1 556567397 17445170 complement(4868877..4869932) 1 NC_022657.1 COG1105 Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB); 1-phosphofructokinase 4869932 17445170 AFR_22495 Actinoplanes friuliensis DSM 7358 1-phosphofructokinase YP_008735822.1 4868877 R 1246995 CDS YP_008735823.1 556567398 17445171 complement(4869938..4870768) 1 NC_022657.1 COG3868 Uncharacterized conserved protein; secreted protein 4870768 17445171 AFR_22500 Actinoplanes friuliensis DSM 7358 secreted protein YP_008735823.1 4869938 R 1246995 CDS YP_008735824.1 556567399 17445172 4871016..4871912 1 NC_022657.1 COG0524 Sugar kinases, ribokinase family; putative carbohydrate kinase 4871912 17445172 AFR_22505 Actinoplanes friuliensis DSM 7358 putative carbohydrate kinase YP_008735824.1 4871016 D 1246995 CDS YP_008735825.1 556567400 17445173 complement(4871909..4872445) 1 NC_022657.1 COG1131 ABC-type multidrug transport system, ATPase component; hypothetical protein 4872445 17445173 AFR_22510 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735825.1 4871909 R 1246995 CDS YP_008735826.1 556567401 17445174 complement(4872606..4873361) 1 NC_022657.1 COG0500 SAM-dependent methyltransferases; type 11 methyltransferase 4873361 17445174 AFR_22515 Actinoplanes friuliensis DSM 7358 type 11 methyltransferase YP_008735826.1 4872606 R 1246995 CDS YP_008735827.1 556567402 17445175 complement(4873369..4874154) 1 NC_022657.1 COG0456 Acetyltransferases; hypothetical protein 4874154 17445175 AFR_22520 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735827.1 4873369 R 1246995 CDS YP_008735828.1 556567403 17445176 complement(4874159..4875367) 1 NC_022657.1 COG1396 Predicted transcriptional regulators; putative DNA-binding protein 4875367 17445176 AFR_22525 Actinoplanes friuliensis DSM 7358 putative DNA-binding protein YP_008735828.1 4874159 R 1246995 CDS YP_008735829.1 556567404 17445177 complement(4875423..4876241) 1 NC_022657.1 COG0395 ABC-type sugar transport system, permease component; binding-protein-dependent transporters inner membrane component 4876241 17445177 AFR_22530 Actinoplanes friuliensis DSM 7358 binding-protein-dependent transporters inner membrane component YP_008735829.1 4875423 R 1246995 CDS YP_008735830.1 556567405 17445178 complement(4876241..4877185) 1 NC_022657.1 COG1175 ABC-type sugar transport systems, permease components; binding-protein-dependent transporters inner membrane component 4877185 17445178 AFR_22535 Actinoplanes friuliensis DSM 7358 binding-protein-dependent transporters inner membrane component YP_008735830.1 4876241 R 1246995 CDS YP_008735831.1 556567406 17445179 complement(4877185..4878504) 1 NC_022657.1 COG1653 ABC-type sugar transport system, periplasmic component; extracellular solute-binding protein 4878504 17445179 AFR_22540 Actinoplanes friuliensis DSM 7358 extracellular solute-binding protein YP_008735831.1 4877185 R 1246995 CDS YP_008735832.1 556567407 17445180 complement(4878545..4879432) 1 NC_022657.1 COG2222 Predicted phosphosugar isomerases; putative phosphosugar isomerase 4879432 17445180 AFR_22545 Actinoplanes friuliensis DSM 7358 putative phosphosugar isomerase YP_008735832.1 4878545 R 1246995 CDS YP_008735833.1 556567408 17445181 complement(4879505..4880797) 1 NC_022657.1 COG1486 Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases; alpha-galactosidase 4880797 17445181 AFR_22550 Actinoplanes friuliensis DSM 7358 alpha-galactosidase YP_008735833.1 4879505 R 1246995 CDS YP_008735834.1 556567409 17445182 4880922..4881698 1 NC_022657.1 COG1349 Transcriptional regulators of sugar metabolism; DeoR family transcriptional regulator 4881698 17445182 AFR_22555 Actinoplanes friuliensis DSM 7358 DeoR family transcriptional regulator YP_008735834.1 4880922 D 1246995 CDS YP_008735835.1 556567410 17445183 4881943..4882650 1 NC_022657.1 COG3201 Nicotinamide mononucleotide transporter; putative nicotinamide mononucleotide transporter 4882650 17445183 AFR_22560 Actinoplanes friuliensis DSM 7358 putative nicotinamide mononucleotide transporter YP_008735835.1 4881943 D 1246995 CDS YP_008735836.1 556567411 17445184 complement(4882647..4883402) 1 NC_022657.1 hypothetical protein 4883402 17445184 AFR_22565 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735836.1 4882647 R 1246995 CDS YP_008735837.1 556567412 17445185 complement(4883399..4883701) 1 NC_022657.1 COG1695 Predicted transcriptional regulators; PadR family transcriptional regulator 4883701 17445185 AFR_22570 Actinoplanes friuliensis DSM 7358 PadR family transcriptional regulator YP_008735837.1 4883399 R 1246995 CDS YP_008735838.1 556567413 17445186 complement(4883739..4884437) 1 NC_022657.1 hypothetical protein 4884437 17445186 AFR_22575 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735838.1 4883739 R 1246995 CDS YP_008735839.1 556567414 17445187 complement(4884483..4885043) 1 NC_022657.1 COG1309 Transcriptional regulator; TetR family transcriptional regulator 4885043 17445187 AFR_22580 Actinoplanes friuliensis DSM 7358 TetR family transcriptional regulator YP_008735839.1 4884483 R 1246995 CDS YP_008735840.1 556567415 17445188 4885095..4886063 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); oxidoreductase 4886063 17445188 AFR_22585 Actinoplanes friuliensis DSM 7358 oxidoreductase YP_008735840.1 4885095 D 1246995 CDS YP_008735841.1 556567416 17445189 complement(4886038..4886226) 1 NC_022657.1 hypothetical protein 4886226 17445189 AFR_22590 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735841.1 4886038 R 1246995 CDS YP_008735842.1 556567417 17445190 complement(4886320..4886706) 1 NC_022657.1 COG0346 Lactoylglutathione lyase and related lyases; glyoxalase/bleomycin resistance protein/dioxygenase 4886706 17445190 AFR_22595 Actinoplanes friuliensis DSM 7358 glyoxalase/bleomycin resistance protein/dioxygenase YP_008735842.1 4886320 R 1246995 CDS YP_008735843.1 556567418 17445191 4887008..4887856 1 NC_022657.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); hypothetical protein 4887856 17445191 AFR_22600 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735843.1 4887008 D 1246995 CDS YP_008735844.1 556567419 17445192 complement(4887873..4888658) 1 NC_022657.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); alpha/beta hydrolase fold protein 4888658 17445192 AFR_22605 Actinoplanes friuliensis DSM 7358 alpha/beta hydrolase fold protein YP_008735844.1 4887873 R 1246995 CDS YP_008735845.1 556567420 17445193 complement(4888882..4889991) 1 NC_022657.1 COG1316 Transcriptional regulator; cell envelope-related transcriptional attenuator 4889991 17445193 AFR_22610 Actinoplanes friuliensis DSM 7358 cell envelope-related transcriptional attenuator YP_008735845.1 4888882 R 1246995 CDS YP_008735846.1 556567421 17445194 4890200..4892320 1 NC_022657.1 COG0465 ATP-dependent Zn proteases; ATP-dependent metalloprotease FtsH 4892320 17445194 AFR_22615 Actinoplanes friuliensis DSM 7358 ATP-dependent metalloprotease FtsH YP_008735846.1 4890200 D 1246995 CDS YP_008735847.1 556567422 17445195 complement(4892582..4893382) 1 NC_022657.1 COG0789 Predicted transcriptional regulators; MerR family transcriptional regulator 4893382 17445195 AFR_22620 Actinoplanes friuliensis DSM 7358 MerR family transcriptional regulator YP_008735847.1 4892582 R 1246995 CDS YP_008735848.1 556567423 17445196 complement(4893389..4894150) 1 NC_022657.1 COG0842 ABC-type multidrug transport system, permease component; ABC transporter permease 4894150 17445196 AFR_22625 Actinoplanes friuliensis DSM 7358 ABC transporter permease YP_008735848.1 4893389 R 1246995 CDS YP_008735849.1 556567424 17445197 complement(4894150..4894917) 1 NC_022657.1 COG1131 ABC-type multidrug transport system, ATPase component; ABC transporter ATP-binding protein 4894917 17445197 AFR_22630 Actinoplanes friuliensis DSM 7358 ABC transporter ATP-binding protein YP_008735849.1 4894150 R 1246995 CDS YP_008735850.1 556567425 17445198 complement(4894963..4896021) 1 NC_022657.1 COG0142 Geranylgeranyl pyrophosphate synthase; polyprenyl synthetase 4896021 17445198 AFR_22635 Actinoplanes friuliensis DSM 7358 polyprenyl synthetase YP_008735850.1 4894963 R 1246995 CDS YP_008735851.1 556567426 17445199 complement(4896030..4897412) 1 NC_022657.1 COG1524 Uncharacterized proteins of the AP superfamily; type I phosphodiesterase/nucleotide pyrophosphatase 4897412 17445199 AFR_22640 Actinoplanes friuliensis DSM 7358 type I phosphodiesterase/nucleotide pyrophosphatase YP_008735851.1 4896030 R 1246995 CDS YP_008735852.1 556567427 17445200 complement(4897409..4898560) 1 NC_022657.1 COG1082 Sugar phosphate isomerases/epimerases; xylose isomerase domain-containing protein 4898560 17445200 AFR_22645 Actinoplanes friuliensis DSM 7358 xylose isomerase domain-containing protein YP_008735852.1 4897409 R 1246995 CDS YP_008735853.1 556567428 17445201 complement(4898560..4899408) 1 NC_022657.1 COG1099 Predicted metal-dependent hydrolases with the TIM-barrel fold; TatD-related deoxyribonuclease 4899408 17445201 AFR_22650 Actinoplanes friuliensis DSM 7358 TatD-related deoxyribonuclease YP_008735853.1 4898560 R 1246995 CDS YP_008735854.1 556567429 17445202 complement(4899408..4900013) 1 NC_022657.1 hypothetical protein 4900013 17445202 AFR_22655 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735854.1 4899408 R 1246995 CDS YP_008735855.1 556567430 17445203 complement(4900010..4900852) 1 NC_022657.1 COG1082 Sugar phosphate isomerases/epimerases; xylose isomerase domain-containing protein 4900852 17445203 AFR_22660 Actinoplanes friuliensis DSM 7358 xylose isomerase domain-containing protein YP_008735855.1 4900010 R 1246995 CDS YP_008735856.1 556567431 17445204 complement(4900849..4901697) 1 NC_022657.1 COG0382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases; UbiA prenyltransferase 4901697 17445204 AFR_22665 Actinoplanes friuliensis DSM 7358 UbiA prenyltransferase YP_008735856.1 4900849 R 1246995 CDS YP_008735857.1 556567432 17445205 complement(4901694..4902830) 1 NC_022657.1 COG1260 Myo-inositol-1-phosphate synthase; myo-inositol-1-phosphate synthase 4902830 17445205 AFR_22670 Actinoplanes friuliensis DSM 7358 myo-inositol-1-phosphate synthase YP_008735857.1 4901694 R 1246995 CDS YP_008735858.1 556567433 17445206 complement(4903072..4904310) 1 NC_022657.1 COG0515 Serine/threonine protein kinase; serine/threonine protein kinase 4904310 17445206 AFR_22675 Actinoplanes friuliensis DSM 7358 serine/threonine protein kinase YP_008735858.1 4903072 R 1246995 CDS YP_008735859.1 556567434 17445207 4904516..4904833 1 NC_022657.1 hypothetical protein 4904833 17445207 AFR_22680 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735859.1 4904516 D 1246995 CDS YP_008735860.1 556567435 17445208 4904830..4906500 1 NC_022657.1 hypothetical protein 4906500 17445208 AFR_22685 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735860.1 4904830 D 1246995 CDS YP_008735861.1 556567436 17445209 4906500..4906985 1 NC_022657.1 hypothetical protein 4906985 17445209 AFR_22690 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735861.1 4906500 D 1246995 CDS YP_008735862.1 556567437 17445210 complement(4906987..4908153) 1 NC_022657.1 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases; FAD-binding monooxygenase protein 4908153 17445210 AFR_22695 Actinoplanes friuliensis DSM 7358 FAD-binding monooxygenase protein YP_008735862.1 4906987 R 1246995 CDS YP_008735863.1 556567438 17445211 4908219..4908824 1 NC_022657.1 COG1309 Transcriptional regulator; TetR family transcriptional regulator 4908824 17445211 AFR_22700 Actinoplanes friuliensis DSM 7358 TetR family transcriptional regulator YP_008735863.1 4908219 D 1246995 CDS YP_008735864.1 556567439 17445212 complement(4908821..4910266) 1 NC_022657.1 hypothetical protein 4910266 17445212 AFR_22705 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735864.1 4908821 R 1246995 CDS YP_008735865.1 556567440 17445213 4910731..4912008 1 NC_022657.1 COG1215 Glycosyltransferases, probably involved in cell wall biogenesis; glycosyl transferase family protein 4912008 17445213 AFR_22710 Actinoplanes friuliensis DSM 7358 glycosyl transferase family protein YP_008735865.1 4910731 D 1246995 CDS YP_008735866.1 556567441 17445214 4912005..4913858 1 NC_022657.1 COG3420 Nitrous oxidase accessory protein; hypothetical protein 4913858 17445214 AFR_22715 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735866.1 4912005 D 1246995 CDS YP_008735867.1 556567442 17445215 4913855..4915018 1 NC_022657.1 hypothetical protein 4915018 17445215 AFR_22720 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735867.1 4913855 D 1246995 CDS YP_008735868.1 556567443 17445216 4915041..4916354 1 NC_022657.1 COG1004 Predicted UDP-glucose 6-dehydrogenase; UDPglucose 6-dehydrogenase 4916354 17445216 AFR_22725 Actinoplanes friuliensis DSM 7358 UDPglucose 6-dehydrogenase YP_008735868.1 4915041 D 1246995 CDS YP_008735869.1 556567444 17445217 complement(4917310..4917780) 1 NC_022657.1 hypothetical protein 4917780 17445217 AFR_22730 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735869.1 4917310 R 1246995 CDS YP_008735870.1 556567445 17445218 complement(4917866..4919125) 1 NC_022657.1 COG0148 Enolase; phosphopyruvate hydratase 4919125 17445218 AFR_22735 Actinoplanes friuliensis DSM 7358 phosphopyruvate hydratase YP_008735870.1 4917866 R 1246995 CDS YP_008735871.1 556567446 17445219 4919243..4920166 1 NC_022657.1 COG0789 Predicted transcriptional regulators; thiol-specific antioxidant-like protein/peroxidoxin BcpB 4920166 17445219 AFR_22740 Actinoplanes friuliensis DSM 7358 thiol-specific antioxidant-like protein/peroxidoxin BcpB YP_008735871.1 4919243 D 1246995 CDS YP_008735872.1 556567447 17445220 4920183..4921346 1 NC_022657.1 COG0303 Molybdopterin biosynthesis enzyme; MoeA domain-containing protein domain I and II 4921346 17445220 AFR_22745 Actinoplanes friuliensis DSM 7358 MoeA domain-containing protein domain I and II YP_008735872.1 4920183 D 1246995 CDS YP_008735873.1 556567448 17445221 4921343..4921945 1 NC_022657.1 COG0500 SAM-dependent methyltransferases; type 11 methyltransferase 4921945 17445221 AFR_22750 Actinoplanes friuliensis DSM 7358 type 11 methyltransferase YP_008735873.1 4921343 D 1246995 CDS YP_008735874.1 556567449 17445222 4922015..4922953 1 NC_022657.1 COG0053 Predicted Co/Zn/Cd cation transporters; putative cation efflux protein 4922953 17445222 AFR_22755 Actinoplanes friuliensis DSM 7358 putative cation efflux protein YP_008735874.1 4922015 D 1246995 CDS YP_008735875.1 556567450 17445223 4923019..4923930 1 NC_022657.1 COG3568 Metal-dependent hydrolase; hypothetical protein 4923930 17445223 AFR_22760 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735875.1 4923019 D 1246995 CDS YP_008735876.1 556567451 17445224 complement(4923998..4925596) 1 NC_022657.1 COG0840 Methyl-accepting chemotaxis protein; Methyl-accepting chemotaxis protein III 4925596 17445224 AFR_22765 Actinoplanes friuliensis DSM 7358 Methyl-accepting chemotaxis protein III YP_008735876.1 4923998 R 1246995 CDS YP_008735877.1 556567452 17445225 4925675..4927906 1 NC_022657.1 COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain; PAS/PAC and GAF sensor-containing diguanylate cyclase/phosphodiesterase 4927906 17445225 AFR_22770 Actinoplanes friuliensis DSM 7358 PAS/PAC and GAF sensor-containing diguanylate cyclase/phosphodiesterase YP_008735877.1 4925675 D 1246995 CDS YP_008735878.1 556567453 17445226 4927959..4930220 1 NC_022657.1 integral membrane protein 4930220 17445226 AFR_22775 Actinoplanes friuliensis DSM 7358 integral membrane protein YP_008735878.1 4927959 D 1246995 CDS YP_008735879.1 556567454 17445227 complement(4930193..4930984) 1 NC_022657.1 hypothetical protein 4930984 17445227 AFR_22780 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735879.1 4930193 R 1246995 CDS YP_008735880.1 556567455 17445228 complement(4931002..4933680) 1 NC_022657.1 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs; putative xanthine dehydrogenase 4933680 17445228 AFR_22785 Actinoplanes friuliensis DSM 7358 putative xanthine dehydrogenase YP_008735880.1 4931002 R 1246995 CDS YP_008735881.1 556567456 17445229 complement(4933677..4934483) 1 NC_022657.1 COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs; putative molybdopterin oxidoreductase 4934483 17445229 AFR_22790 Actinoplanes friuliensis DSM 7358 putative molybdopterin oxidoreductase YP_008735881.1 4933677 R 1246995 CDS YP_008735882.1 556567457 17445230 4934612..4935241 1 NC_022657.1 COG3642 Mn2+-dependent serine/threonine protein kinase; aminoglycoside phosphotransferase 4935241 17445230 AFR_22795 Actinoplanes friuliensis DSM 7358 aminoglycoside phosphotransferase YP_008735882.1 4934612 D 1246995 CDS YP_008735883.1 556567458 17445231 4935243..4936181 1 NC_022657.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); hypothetical protein 4936181 17445231 AFR_22800 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735883.1 4935243 D 1246995 CDS YP_008735884.1 556567459 17445232 4936178..4937386 1 NC_022657.1 COG0531 Amino acid transporters; hypothetical protein 4937386 17445232 AFR_22805 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735884.1 4936178 D 1246995 CDS YP_008735885.1 556567460 17445233 4937507..4938151 1 NC_022657.1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; two component transcriptional regulator 4938151 17445233 AFR_22810 Actinoplanes friuliensis DSM 7358 two component transcriptional regulator YP_008735885.1 4937507 D 1246995 CDS YP_008735886.1 556567461 17445234 4938151..4938903 1 NC_022657.1 COG0846 NAD-dependent protein deacetylases, SIR2 family; silent information regulator protein Sir2 4938903 17445234 AFR_22815 Actinoplanes friuliensis DSM 7358 silent information regulator protein Sir2 YP_008735886.1 4938151 D 1246995 CDS YP_008735887.1 556567462 17445235 4939365..4939895 1 NC_022657.1 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; RNA polymerase sigma-E factor 4939895 17445235 AFR_22820 Actinoplanes friuliensis DSM 7358 RNA polymerase sigma-E factor YP_008735887.1 4939365 D 1246995 CDS YP_008735888.1 556567463 17445236 complement(4939933..4940124) 1 NC_022657.1 hypothetical protein 4940124 17445236 AFR_22825 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735888.1 4939933 R 1246995 CDS YP_008735889.1 556567464 17445237 complement(4940124..4940918) 1 NC_022657.1 hypothetical protein 4940918 17445237 AFR_22830 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735889.1 4940124 R 1246995 CDS YP_008735890.1 556567465 17445238 complement(4940912..4941202) 1 NC_022657.1 COG1695 Predicted transcriptional regulators; PadR-like family transcriptional regulator 4941202 17445238 AFR_22835 Actinoplanes friuliensis DSM 7358 PadR-like family transcriptional regulator YP_008735890.1 4940912 R 1246995 CDS YP_008735891.1 556567466 17445239 4941290..4941835 1 NC_022657.1 hypothetical protein 4941835 17445239 AFR_22840 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735891.1 4941290 D 1246995 CDS YP_008735892.1 556567467 17445240 complement(4941838..4942701) 1 NC_022657.1 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; RNA polymerase factor sigma-70 4942701 17445240 AFR_22845 Actinoplanes friuliensis DSM 7358 RNA polymerase factor sigma-70 YP_008735892.1 4941838 R 1246995 CDS YP_008735893.1 556567468 17445241 complement(4942710..4943537) 1 NC_022657.1 COG0657 Esterase/lipase; esterase 4943537 17445241 AFR_22850 Actinoplanes friuliensis DSM 7358 esterase YP_008735893.1 4942710 R 1246995 CDS YP_008735894.1 556567469 17445242 complement(4943584..4944054) 1 NC_022657.1 hypothetical protein 4944054 17445242 AFR_22855 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735894.1 4943584 R 1246995 CDS YP_008735895.1 556567470 17445243 complement(4944051..4944641) 1 NC_022657.1 COG0558 Phosphatidylglycerophosphate synthase; CDP-alcohol phosphatidyltransferase 4944641 17445243 AFR_22860 Actinoplanes friuliensis DSM 7358 CDP-alcohol phosphatidyltransferase YP_008735895.1 4944051 R 1246995 CDS YP_008735896.1 556567471 17445244 complement(4944638..4944865) 1 NC_022657.1 hypothetical protein 4944865 17445244 AFR_22865 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735896.1 4944638 R 1246995 CDS YP_008735897.1 556567472 17445245 complement(4944866..4945219) 1 NC_022657.1 COG0640 Predicted transcriptional regulators; ArsR family transcriptional regulator 4945219 17445245 AFR_22870 Actinoplanes friuliensis DSM 7358 ArsR family transcriptional regulator YP_008735897.1 4944866 R 1246995 CDS YP_008735898.1 556567473 17445246 4945294..4946136 1 NC_022657.1 COG1752 Predicted esterase of the alpha-beta hydrolase superfamily; putative patatin-like phospholipase 4946136 17445246 AFR_22875 Actinoplanes friuliensis DSM 7358 putative patatin-like phospholipase YP_008735898.1 4945294 D 1246995 CDS YP_008735899.1 556567474 17445247 complement(4946138..4948567) 1 NC_022657.1 COG3957 Phosphoketolase; phosphoketolase 4948567 17445247 AFR_22880 Actinoplanes friuliensis DSM 7358 phosphoketolase YP_008735899.1 4946138 R 1246995 CDS YP_008735900.1 556567475 17445248 complement(4948702..4949553) 1 NC_022657.1 COG1396 Predicted transcriptional regulators; DNA-binding protein 4949553 17445248 AFR_22885 Actinoplanes friuliensis DSM 7358 DNA-binding protein YP_008735900.1 4948702 R 1246995 CDS YP_008735901.1 556567476 17445249 4949681..4950676 1 NC_022657.1 COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases); oxidoreductase 4950676 17445249 AFR_22890 Actinoplanes friuliensis DSM 7358 oxidoreductase YP_008735901.1 4949681 D 1246995 CDS YP_008735902.1 556567477 17445250 complement(4950684..4951301) 1 NC_022657.1 COG0702 Predicted nucleoside-diphosphate-sugar epimerases; Flavin reductase 4951301 17445250 AFR_22895 Actinoplanes friuliensis DSM 7358 Flavin reductase YP_008735902.1 4950684 R 1246995 CDS YP_008735903.1 556567478 17445251 complement(4951301..4952080) 1 NC_022657.1 COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family; myo-inositol-1(or 4)-monophosphatase 4952080 17445251 AFR_22900 Actinoplanes friuliensis DSM 7358 myo-inositol-1(or 4)-monophosphatase YP_008735903.1 4951301 R 1246995 CDS YP_008735904.1 556567479 17445252 4952167..4953054 1 NC_022657.1 COG0583 Transcriptional regulator; LysR family transcriptional regulator 4953054 17445252 AFR_22905 Actinoplanes friuliensis DSM 7358 LysR family transcriptional regulator YP_008735904.1 4952167 D 1246995 CDS YP_008735905.1 556567480 17445253 4953064..4953630 1 NC_022657.1 COG1396 Predicted transcriptional regulators; XRE family transcriptional regulator 4953630 17445253 AFR_22910 Actinoplanes friuliensis DSM 7358 XRE family transcriptional regulator YP_008735905.1 4953064 D 1246995 CDS YP_008735906.1 556567481 17445254 4953709..4955220 1 NC_022657.1 COG0477 Permeases of the major facilitator superfamily; EmrB/QacA subfamily drug resistance transporter 4955220 17445254 AFR_22915 Actinoplanes friuliensis DSM 7358 EmrB/QacA subfamily drug resistance transporter YP_008735906.1 4953709 D 1246995 CDS YP_008735907.1 556567482 17445255 4955230..4955817 1 NC_022657.1 COG3231 Aminoglycoside phosphotransferase; Trifolitoxin immunity protein 4955817 17445255 AFR_22920 Actinoplanes friuliensis DSM 7358 Trifolitoxin immunity protein YP_008735907.1 4955230 D 1246995 CDS YP_008735908.1 556567483 17445256 4955947..4956978 1 NC_022657.1 hypothetical protein 4956978 17445256 AFR_22925 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735908.1 4955947 D 1246995 CDS YP_008735909.1 556567484 17445257 complement(4956989..4957771) 1 NC_022657.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); alpha/beta hydrolase fold protein 4957771 17445257 AFR_22930 Actinoplanes friuliensis DSM 7358 alpha/beta hydrolase fold protein YP_008735909.1 4956989 R 1246995 CDS YP_008735910.1 556567485 17445258 4957906..4958277 1 NC_022657.1 hypothetical protein 4958277 17445258 AFR_22935 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735910.1 4957906 D 1246995 CDS YP_008735911.1 556567486 17445259 4958308..4958616 1 NC_022657.1 COG5485 Predicted ester cyclase; hypothetical protein 4958616 17445259 AFR_22940 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735911.1 4958308 D 1246995 CDS YP_008735912.1 556567487 17445260 complement(4958621..4959640) 1 NC_022657.1 COG1064 Zn-dependent alcohol dehydrogenases; alcohol dehydrogenase 4959640 17445260 AFR_22945 Actinoplanes friuliensis DSM 7358 alcohol dehydrogenase YP_008735912.1 4958621 R 1246995 CDS YP_008735913.1 556567488 17445261 4959790..4960644 1 NC_022657.1 COG1396 Predicted transcriptional regulators; XRE family transcriptional regulator 4960644 17445261 AFR_22950 Actinoplanes friuliensis DSM 7358 XRE family transcriptional regulator YP_008735913.1 4959790 D 1246995 CDS YP_008735914.1 556567489 17445262 4960701..4961120 1 NC_022657.1 hypothetical protein 4961120 17445262 AFR_22955 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735914.1 4960701 D 1246995 CDS YP_008735915.1 556567490 17445263 4961211..4973363 1 NC_022657.1 COG3391 Uncharacterized conserved protein; fibronectin type III domain-containing protein 4973363 17445263 AFR_22960 Actinoplanes friuliensis DSM 7358 fibronectin type III domain-containing protein YP_008735915.1 4961211 D 1246995 CDS YP_008735916.1 556567491 17445264 4973408..4973953 1 NC_022657.1 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins; GCN5-like N-acetyltransferase 4973953 17445264 AFR_22965 Actinoplanes friuliensis DSM 7358 GCN5-like N-acetyltransferase YP_008735916.1 4973408 D 1246995 CDS YP_008735917.1 556567492 17445265 complement(4974068..4975513) 1 NC_022657.1 COG2730 Endoglucanase; Endoglucanase celA precursor 4975513 17445265 AFR_22970 Actinoplanes friuliensis DSM 7358 Endoglucanase celA precursor YP_008735917.1 4974068 R 1246995 CDS YP_008735918.1 556567493 17445266 complement(4975671..4977149) 1 NC_022657.1 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases; 3-(3-hydroxy-phenyl)propionate hydroxylase 4977149 17445266 AFR_22975 Actinoplanes friuliensis DSM 7358 3-(3-hydroxy-phenyl)propionate hydroxylase YP_008735918.1 4975671 R 1246995 CDS YP_008735919.1 556567494 17445267 complement(4977136..4977822) 1 NC_022657.1 COG1309 Transcriptional regulator; TetR family transcriptional regulator 4977822 17445267 AFR_22980 Actinoplanes friuliensis DSM 7358 TetR family transcriptional regulator YP_008735919.1 4977136 R 1246995 CDS YP_008735920.1 556567495 17445268 complement(4977849..4978892) 1 NC_022657.1 COG2334 Putative homoserine kinase type II (protein kinase fold); aminoglycoside phosphotransferase 4978892 17445268 AFR_22985 Actinoplanes friuliensis DSM 7358 aminoglycoside phosphotransferase YP_008735920.1 4977849 R 1246995 CDS YP_008735921.1 556567496 17445269 4979021..4979650 1 NC_022657.1 COG0586 Uncharacterized membrane-associated protein; hypothetical protein 4979650 17445269 AFR_22990 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735921.1 4979021 D 1246995 CDS YP_008735922.1 556567497 17445270 4979660..4979983 1 NC_022657.1 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); Anti-sigma F factor antagonist 4979983 17445270 AFR_22995 Actinoplanes friuliensis DSM 7358 Anti-sigma F factor antagonist YP_008735922.1 4979660 D 1246995 CDS YP_008735923.1 556567498 17445271 complement(4979990..4980706) 1 NC_022657.1 COG1266 Predicted metal-dependent membrane protease; abortive infection protein 4980706 17445271 AFR_23000 Actinoplanes friuliensis DSM 7358 abortive infection protein YP_008735923.1 4979990 R 1246995 CDS YP_008735924.1 556567499 17445272 complement(4980703..4981623) 1 NC_022657.1 COG0702 Predicted nucleoside-diphosphate-sugar epimerases; NAD-dependent epimerase/dehydratase 4981623 17445272 AFR_23005 Actinoplanes friuliensis DSM 7358 NAD-dependent epimerase/dehydratase YP_008735924.1 4980703 R 1246995 CDS YP_008735925.1 556567500 17445273 complement(4981713..4982327) 1 NC_022657.1 COG1309 Transcriptional regulator; putative TetR-family transcriptional regulator 4982327 17445273 AFR_23010 Actinoplanes friuliensis DSM 7358 putative TetR-family transcriptional regulator YP_008735925.1 4981713 R 1246995 CDS YP_008735926.1 556567501 17445274 4982386..4983084 1 NC_022657.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); putative alpha/beta hydrolase family protein 4983084 17445274 AFR_23015 Actinoplanes friuliensis DSM 7358 putative alpha/beta hydrolase family protein YP_008735926.1 4982386 D 1246995 CDS YP_008735927.1 556567502 17445275 complement(4983427..4985157) 1 NC_022657.1 COG2258 Uncharacterized protein conserved in bacteria; MOSC domain-containing protein 4985157 17445275 AFR_23020 Actinoplanes friuliensis DSM 7358 MOSC domain-containing protein YP_008735927.1 4983427 R 1246995 CDS YP_008735928.1 556567503 17445276 complement(4985168..4985890) 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); alcohol dehydrogenase 4985890 17445276 AFR_23025 Actinoplanes friuliensis DSM 7358 alcohol dehydrogenase YP_008735928.1 4985168 R 1246995 CDS YP_008735929.1 556567504 17445277 complement(4985887..4987359) 1 NC_022657.1 COG0477 Permeases of the major facilitator superfamily; transmembrane efflux protein 4987359 17445277 AFR_23030 Actinoplanes friuliensis DSM 7358 transmembrane efflux protein YP_008735929.1 4985887 R 1246995 CDS YP_008735930.1 556567505 17445278 complement(4987356..4987868) 1 NC_022657.1 hypothetical protein 4987868 17445278 AFR_23035 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735930.1 4987356 R 1246995 CDS YP_008735931.1 556567506 17445279 complement(4987883..4988608) 1 NC_022657.1 COG4221 Short-chain alcohol dehydrogenase of unknown specificity; short-chain dehydrogenase/reductase SDR 4988608 17445279 AFR_23040 Actinoplanes friuliensis DSM 7358 short-chain dehydrogenase/reductase SDR YP_008735931.1 4987883 R 1246995 CDS YP_008735932.1 556567507 17445280 complement(4988605..4989222) 1 NC_022657.1 COG0346 Lactoylglutathione lyase and related lyases; hypothetical protein 4989222 17445280 AFR_23045 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735932.1 4988605 R 1246995 CDS YP_008735933.1 556567508 17445281 complement(4989311..4991983) 1 NC_022657.1 COG2771 DNA-binding HTH domain-containing proteins; ATPase-like protein 4991983 17445281 AFR_23050 Actinoplanes friuliensis DSM 7358 ATPase-like protein YP_008735933.1 4989311 R 1246995 CDS YP_008735934.1 556567509 17445282 4992301..4993518 1 NC_022657.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); hydrolase 4993518 17445282 AFR_23055 Actinoplanes friuliensis DSM 7358 hydrolase YP_008735934.1 4992301 D 1246995 CDS YP_008735935.1 556567510 17445283 4993515..4994774 1 NC_022657.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); putative epoxide hydrolase 4994774 17445283 AFR_23060 Actinoplanes friuliensis DSM 7358 putative epoxide hydrolase YP_008735935.1 4993515 D 1246995 CDS YP_008735936.1 556567511 17445284 complement(4994780..4995232) 1 NC_022657.1 COG0406 Fructose-2,6-bisphosphatase; phosphoglycerate mutase 4995232 17445284 AFR_23065 Actinoplanes friuliensis DSM 7358 phosphoglycerate mutase YP_008735936.1 4994780 R 1246995 CDS YP_008735937.1 556567512 17445285 complement(4995353..4996141) 1 NC_022657.1 COG1387 Histidinol phosphatase and related hydrolases of the PHP family; histidinol-phosphatase (PHP family) protein 4996141 17445285 AFR_23070 Actinoplanes friuliensis DSM 7358 histidinol-phosphatase (PHP family) protein YP_008735937.1 4995353 R 1246995 CDS YP_008735938.1 556567513 17445286 complement(4996198..4996974) 1 NC_022657.1 hypothetical protein 4996974 17445286 AFR_23075 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735938.1 4996198 R 1246995 CDS YP_008735939.1 556567514 17445287 complement(4997000..4997599) 1 NC_022657.1 COG1309 Transcriptional regulator; hypothetical protein 4997599 17445287 AFR_23080 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735939.1 4997000 R 1246995 CDS YP_008735940.1 556567515 17445288 4997826..4998344 1 NC_022657.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); hypothetical protein 4998344 17445288 AFR_23085 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735940.1 4997826 D 1246995 CDS YP_008735941.1 556567516 17445289 4998341..4998682 1 NC_022657.1 hypothetical protein 4998682 17445289 AFR_23090 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735941.1 4998341 D 1246995 CDS YP_008735942.1 556567517 17445290 4998811..5000916 1 NC_022657.1 COG2409 Predicted drug exporters of the RND superfamily; drug exporter of the RND superfamily-like protein 5000916 17445290 AFR_23095 Actinoplanes friuliensis DSM 7358 drug exporter of the RND superfamily-like protein YP_008735942.1 4998811 D 1246995 CDS YP_008735943.1 556567518 17445291 complement(5002865..5003197) 1 NC_022657.1 glyoxalase/bleomycin resistance protein/dioxygenase 5003197 17445291 AFR_23100 Actinoplanes friuliensis DSM 7358 glyoxalase/bleomycin resistance protein/dioxygenase YP_008735943.1 5002865 R 1246995 CDS YP_008735944.1 556567519 17445292 complement(5003203..5003772) 1 NC_022657.1 COG1309 Transcriptional regulator; TetR family transcriptional regulator 5003772 17445292 AFR_23105 Actinoplanes friuliensis DSM 7358 TetR family transcriptional regulator YP_008735944.1 5003203 R 1246995 CDS YP_008735945.1 556567520 17445293 5003877..5004752 1 NC_022657.1 COG4188 Predicted dienelactone hydrolase; hypothetical protein 5004752 17445293 AFR_23110 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735945.1 5003877 D 1246995 CDS YP_008735946.1 556567521 17445294 5004770..5005618 1 NC_022657.1 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases; luciferase-like protein 5005618 17445294 AFR_23115 Actinoplanes friuliensis DSM 7358 luciferase-like protein YP_008735946.1 5004770 D 1246995 CDS YP_008735947.1 556567522 17445295 complement(5005604..5006074) 1 NC_022657.1 COG1846 Transcriptional regulators; MarR family transcriptional regulator 5006074 17445295 AFR_23120 Actinoplanes friuliensis DSM 7358 MarR family transcriptional regulator YP_008735947.1 5005604 R 1246995 CDS YP_008735948.1 556567523 17445296 5006171..5006785 1 NC_022657.1 COG0778 Nitroreductase; malonic semialdehyde reductase 5006785 17445296 AFR_23125 Actinoplanes friuliensis DSM 7358 malonic semialdehyde reductase YP_008735948.1 5006171 D 1246995 CDS YP_008735949.1 556567524 17445297 5006829..5007503 1 NC_022657.1 hypothetical protein 5007503 17445297 AFR_23130 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735949.1 5006829 D 1246995 CDS YP_008735950.1 556567525 17445298 5007500..5007832 1 NC_022657.1 COG1846 Transcriptional regulators; hypothetical protein 5007832 17445298 AFR_23135 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735950.1 5007500 D 1246995 CDS YP_008735951.1 556567526 17445299 5007835..5008974 1 NC_022657.1 COG4188 Predicted dienelactone hydrolase; lipase 5008974 17445299 AFR_23140 Actinoplanes friuliensis DSM 7358 lipase YP_008735951.1 5007835 D 1246995 CDS YP_008735952.1 556567527 17445300 complement(5009597..5010250) 1 NC_022657.1 COG1182 Acyl carrier protein phosphodiesterase; putative acyl carrier protein phosphodiesterase 5010250 17445300 AFR_23145 Actinoplanes friuliensis DSM 7358 putative acyl carrier protein phosphodiesterase YP_008735952.1 5009597 R 1246995 CDS YP_008735953.1 556567528 17445301 5010365..5010868 1 NC_022657.1 COG1846 Transcriptional regulators; putative MarR-family transcriptional regulator 5010868 17445301 AFR_23150 Actinoplanes friuliensis DSM 7358 putative MarR-family transcriptional regulator YP_008735953.1 5010365 D 1246995 CDS YP_008735954.1 556567529 17445302 5010915..5011460 1 NC_022657.1 COG1695 Predicted transcriptional regulators; putative PadR-like family transcriptional regulator 5011460 17445302 AFR_23155 Actinoplanes friuliensis DSM 7358 putative PadR-like family transcriptional regulator YP_008735954.1 5010915 D 1246995 CDS YP_008735955.1 556567530 17445303 5011496..5013217 1 NC_022657.1 COG1960 Acyl-CoA dehydrogenases; acyl-CoA dehydrogenase 5013217 17445303 AFR_23160 Actinoplanes friuliensis DSM 7358 acyl-CoA dehydrogenase YP_008735955.1 5011496 D 1246995 CDS YP_008735956.1 556567531 17445304 complement(5013214..5013915) 1 NC_022657.1 glyoxalase/bleomycin resistance protein/dioxygenase 5013915 17445304 AFR_23165 Actinoplanes friuliensis DSM 7358 glyoxalase/bleomycin resistance protein/dioxygenase YP_008735956.1 5013214 R 1246995 CDS YP_008735957.1 556567532 17445305 5014014..5014859 1 NC_022657.1 COG0842 ABC-type multidrug transport system, permease component; ABC-2 type transporter 5014859 17445305 AFR_23170 Actinoplanes friuliensis DSM 7358 ABC-2 type transporter YP_008735957.1 5014014 D 1246995 CDS YP_008735958.1 556567533 17445306 complement(5014846..5015766) 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); short chain dehydrogenase 5015766 17445306 AFR_23175 Actinoplanes friuliensis DSM 7358 short chain dehydrogenase YP_008735958.1 5014846 R 1246995 CDS YP_008735959.1 556567534 17445307 5015902..5016786 1 NC_022657.1 COG1396 Predicted transcriptional regulators; helix-turn-helix domain-containing protein 5016786 17445307 AFR_23180 Actinoplanes friuliensis DSM 7358 helix-turn-helix domain-containing protein YP_008735959.1 5015902 D 1246995 CDS YP_008735960.1 556567535 17445308 5016810..5018834 1 NC_022657.1 COG2217 Cation transport ATPase; heavy metal translocating p-type ATPase 5018834 17445308 AFR_23185 Actinoplanes friuliensis DSM 7358 heavy metal translocating p-type ATPase YP_008735960.1 5016810 D 1246995 CDS YP_008735961.1 556567536 17445309 5019175..5019387 1 NC_022657.1 hypothetical protein 5019387 17445309 AFR_23190 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735961.1 5019175 D 1246995 CDS YP_008735962.1 556567537 17445310 complement(5019283..5021220) 1 NC_022657.1 COG1404 Subtilisin-like serine proteases; peptidase S8/S53 subtilisin kexin sedolisin 5021220 17445310 AFR_23195 Actinoplanes friuliensis DSM 7358 peptidase S8/S53 subtilisin kexin sedolisin YP_008735962.1 5019283 R 1246995 CDS YP_008735963.1 556567538 17445311 complement(5021223..5022083) 1 NC_022657.1 hypothetical protein 5022083 17445311 AFR_23200 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735963.1 5021223 R 1246995 CDS YP_008735964.1 556567539 17445312 complement(5022110..5022466) 1 NC_022657.1 COG1496 Uncharacterized conserved protein; hypothetical protein 5022466 17445312 AFR_23205 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735964.1 5022110 R 1246995 CDS YP_008735965.1 556567540 17445313 complement(5022459..5023109) 1 NC_022657.1 hypothetical protein 5023109 17445313 AFR_23210 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735965.1 5022459 R 1246995 CDS YP_008735966.1 556567541 17445314 5023305..5024351 1 NC_022657.1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; GAF sensor hybrid histidine kinase 5024351 17445314 AFR_23215 Actinoplanes friuliensis DSM 7358 GAF sensor hybrid histidine kinase YP_008735966.1 5023305 D 1246995 CDS YP_008735967.1 556567542 17445315 5024360..5025220 1 NC_022657.1 COG0191 Fructose/tagatose bisphosphate aldolase; ketose-bisphosphate aldolase 5025220 17445315 AFR_23220 Actinoplanes friuliensis DSM 7358 ketose-bisphosphate aldolase YP_008735967.1 5024360 D 1246995 CDS YP_008735968.1 556567543 17445316 5025217..5025984 1 NC_022657.1 COG0637 Predicted phosphatase/phosphohexomutase; HAD-superfamily hydrolase 5025984 17445316 AFR_23225 Actinoplanes friuliensis DSM 7358 HAD-superfamily hydrolase YP_008735968.1 5025217 D 1246995 CDS YP_008735969.1 556567544 17445317 5025981..5026631 1 NC_022657.1 COG2376 Dihydroxyacetone kinase; dihydroxyacetone kinase subunit L 5026631 17445317 AFR_23230 Actinoplanes friuliensis DSM 7358 dihydroxyacetone kinase subunit L YP_008735969.1 5025981 D 1246995 CDS YP_008735970.1 556567545 17445318 5026628..5027623 1 NC_022657.1 COG2376 Dihydroxyacetone kinase; dihydroxyacetone kinase subunit DhaK 5027623 17445318 AFR_23235 Actinoplanes friuliensis DSM 7358 dihydroxyacetone kinase subunit DhaK YP_008735970.1 5026628 D 1246995 CDS YP_008735971.1 556567546 17445319 5027763..5028395 1 NC_022657.1 hypothetical protein 5028395 17445319 AFR_23240 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735971.1 5027763 D 1246995 CDS YP_008735972.1 556567547 17445320 5028417..5028794 1 NC_022657.1 COG0640 Predicted transcriptional regulators; putative transcriptional regulator 5028794 17445320 AFR_23245 Actinoplanes friuliensis DSM 7358 putative transcriptional regulator YP_008735972.1 5028417 D 1246995 CDS YP_008735973.1 556567548 17445321 5028791..5029285 1 NC_022657.1 COG3832 Uncharacterized conserved protein; hypothetical protein 5029285 17445321 AFR_23250 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735973.1 5028791 D 1246995 CDS YP_008735974.1 556567549 17445322 5029337..5030701 1 NC_022657.1 COG2133 Glucose/sorbosone dehydrogenases; L-sorbosone dehydrogenase 5030701 17445322 AFR_23255 Actinoplanes friuliensis DSM 7358 L-sorbosone dehydrogenase YP_008735974.1 5029337 D 1246995 CDS YP_008735975.1 556567550 17445323 complement(5030688..5030963) 1 NC_022657.1 hypothetical protein 5030963 17445323 AFR_23260 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735975.1 5030688 R 1246995 CDS YP_008735976.1 556567551 17445324 5031037..5032023 1 NC_022657.1 COG1273 Uncharacterized conserved protein; Ku protein 5032023 17445324 AFR_23265 Actinoplanes friuliensis DSM 7358 Ku protein YP_008735976.1 5031037 D 1246995 CDS YP_008735977.1 556567552 17445325 5032059..5032508 1 NC_022657.1 hypothetical protein 5032508 17445325 AFR_23270 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735977.1 5032059 D 1246995 CDS YP_008735978.1 556567553 17445326 5032531..5033427 1 NC_022657.1 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases; luciferase-like monooxygenase 5033427 17445326 AFR_23275 Actinoplanes friuliensis DSM 7358 luciferase-like monooxygenase YP_008735978.1 5032531 D 1246995 CDS YP_008735979.1 556567554 17445327 5033469..5034287 1 NC_022657.1 COG0491 Zn-dependent hydrolases, including glyoxylases; beta-lactamase domain-containing protein 5034287 17445327 AFR_23280 Actinoplanes friuliensis DSM 7358 beta-lactamase domain-containing protein YP_008735979.1 5033469 D 1246995 CDS YP_008735980.1 556567555 17445328 5034309..5035922 1 NC_022657.1 COG1502 Phosphatidylserine/phosphatidylglycerophosphate/cardiolipi n synthases and related enzymes; hypothetical protein 5035922 17445328 AFR_23285 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735980.1 5034309 D 1246995 CDS YP_008735981.1 556567556 17445329 complement(5035883..5037874) 1 NC_022657.1 COG1960 Acyl-CoA dehydrogenases; acyl-CoA oxidase 5037874 17445329 AFR_23290 Actinoplanes friuliensis DSM 7358 acyl-CoA oxidase YP_008735981.1 5035883 R 1246995 CDS YP_008735982.1 556567557 17445330 5037931..5038728 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); short-chain dehydrogenase/reductase SDR 5038728 17445330 AFR_23295 Actinoplanes friuliensis DSM 7358 short-chain dehydrogenase/reductase SDR YP_008735982.1 5037931 D 1246995 CDS YP_008735983.1 556567558 17445331 5038804..5039664 1 NC_022657.1 hypothetical protein 5039664 17445331 AFR_23300 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735983.1 5038804 D 1246995 CDS YP_008735984.1 556567559 17445332 complement(5039642..5040466) 1 NC_022657.1 COG0463 Glycosyltransferases involved in cell wall biogenesis; glycosyltransferase 5040466 17445332 AFR_23305 Actinoplanes friuliensis DSM 7358 glycosyltransferase YP_008735984.1 5039642 R 1246995 CDS YP_008735985.1 556567560 17445333 complement(5040463..5041434) 1 NC_022657.1 glycosyl transferase 5041434 17445333 AFR_23310 Actinoplanes friuliensis DSM 7358 glycosyl transferase YP_008735985.1 5040463 R 1246995 CDS YP_008735986.1 556567561 17445334 complement(5041431..5042576) 1 NC_022657.1 COG0438 Glycosyltransferase; glycosyltransferase 5042576 17445334 AFR_23315 Actinoplanes friuliensis DSM 7358 glycosyltransferase YP_008735986.1 5041431 R 1246995 CDS YP_008735987.1 556567562 17445335 complement(5042573..5043661) 1 NC_022657.1 methyl-accepting chemotaxis protein 5043661 17445335 AFR_23320 Actinoplanes friuliensis DSM 7358 methyl-accepting chemotaxis protein YP_008735987.1 5042573 R 1246995 CDS YP_008735988.1 556567563 17445336 5043833..5044747 1 NC_022657.1 peptide ABC transporter ATPase 5044747 17445336 AFR_23325 Actinoplanes friuliensis DSM 7358 peptide ABC transporter ATPase YP_008735988.1 5043833 D 1246995 CDS YP_008735989.1 556567564 17445337 5044744..5045733 1 NC_022657.1 permease 5045733 17445337 AFR_23330 Actinoplanes friuliensis DSM 7358 permease YP_008735989.1 5044744 D 1246995 CDS YP_008735990.1 556567565 17445338 5045727..5047016 1 NC_022657.1 COG0463 Glycosyltransferases involved in cell wall biogenesis; glycosyltransferase 5047016 17445338 AFR_23335 Actinoplanes friuliensis DSM 7358 glycosyltransferase YP_008735990.1 5045727 D 1246995 CDS YP_008735991.1 556567566 17445339 5047066..5047716 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); short-chain dehydrogenase/reductase SDR 5047716 17445339 AFR_23340 Actinoplanes friuliensis DSM 7358 short-chain dehydrogenase/reductase SDR YP_008735991.1 5047066 D 1246995 CDS YP_008735992.1 556567567 17445340 5047846..5048070 1 NC_022657.1 hypothetical protein 5048070 17445340 AFR_23345 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735992.1 5047846 D 1246995 CDS YP_008735993.1 556567568 17445341 complement(5048129..5048311) 1 NC_022657.1 hypothetical protein 5048311 17445341 AFR_23350 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735993.1 5048129 R 1246995 CDS YP_008735994.1 556567569 17445342 5048535..5048903 1 NC_022657.1 hypothetical protein 5048903 17445342 AFR_23355 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735994.1 5048535 D 1246995 CDS YP_008735995.1 556567570 17445343 5048903..5051035 1 NC_022657.1 hypothetical protein 5051035 17445343 AFR_23360 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735995.1 5048903 D 1246995 CDS YP_008735996.1 556567571 17445344 5051163..5051750 1 NC_022657.1 hypothetical protein 5051750 17445344 AFR_23365 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735996.1 5051163 D 1246995 CDS YP_008735997.1 556567572 17445345 5051826..5052029 1 NC_022657.1 hypothetical protein 5052029 17445345 AFR_23370 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735997.1 5051826 D 1246995 CDS YP_008735998.1 556567573 17445346 5052620..5053069 1 NC_022657.1 COG3293 Transposase and inactivated derivatives; transposase 5053069 17445346 AFR_23375 Actinoplanes friuliensis DSM 7358 transposase YP_008735998.1 5052620 D 1246995 CDS YP_008735999.1 556567574 17445347 complement(5053139..5053504) 1 NC_022657.1 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); hypothetical protein 5053504 17445347 AFR_23380 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008735999.1 5053139 R 1246995 CDS YP_008736000.1 556567575 17445348 5053664..5054053 1 NC_022657.1 COG0642 Signal transduction histidine kinase; histidine kinase 5054053 17445348 AFR_23385 Actinoplanes friuliensis DSM 7358 histidine kinase YP_008736000.1 5053664 D 1246995 CDS YP_008736001.1 556567576 17445349 complement(5054050..5054892) 1 NC_022657.1 COG1216 Predicted glycosyltransferases; glycosyl transferase family protein 5054892 17445349 AFR_23390 Actinoplanes friuliensis DSM 7358 glycosyl transferase family protein YP_008736001.1 5054050 R 1246995 CDS YP_008736002.1 556567577 17445350 complement(5054900..5057158) 1 NC_022657.1 COG0753 Catalase; catalase 5057158 17445350 AFR_23395 Actinoplanes friuliensis DSM 7358 catalase YP_008736002.1 5054900 R 1246995 CDS YP_008736003.1 556567578 17445351 5057399..5059219 1 NC_022657.1 COG5520 O-Glycosyl hydrolase; glucan endo-1,6-beta-glucosidase 5059219 17445351 AFR_23400 Actinoplanes friuliensis DSM 7358 glucan endo-1,6-beta-glucosidase YP_008736003.1 5057399 D 1246995 CDS YP_008736004.1 556567579 17445352 complement(5059268..5060461) 1 NC_022657.1 hypothetical protein 5060461 17445352 AFR_23405 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736004.1 5059268 R 1246995 CDS YP_008736005.1 556567580 17445353 complement(5060523..5061326) 1 NC_022657.1 COG2513 PEP phosphonomutase and related enzymes; methylisocitrate lyase 5061326 17445353 AFR_23410 Actinoplanes friuliensis DSM 7358 methylisocitrate lyase YP_008736005.1 5060523 R 1246995 CDS YP_008736006.1 556567581 17445354 5061376..5062413 1 NC_022657.1 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases; alcohol dehydrogenase zinc-binding domain-containing protein 5062413 17445354 AFR_23415 Actinoplanes friuliensis DSM 7358 alcohol dehydrogenase zinc-binding domain-containing protein YP_008736006.1 5061376 D 1246995 CDS YP_008736007.1 556567582 17445355 5062576..5063055 1 NC_022657.1 hypothetical protein 5063055 17445355 AFR_23420 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736007.1 5062576 D 1246995 CDS YP_008736008.1 556567583 17445356 5063567..5064214 1 NC_022657.1 COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase; glycosyl transferase family protein 5064214 17445356 AFR_23425 Actinoplanes friuliensis DSM 7358 glycosyl transferase family protein YP_008736008.1 5063567 D 1246995 CDS YP_008736009.1 556567584 17445357 5064211..5066376 1 NC_022657.1 COG3973 Superfamily I DNA and RNA helicases; superfamily I DNA and RNA helicase 5066376 17445357 AFR_23430 Actinoplanes friuliensis DSM 7358 superfamily I DNA and RNA helicase YP_008736009.1 5064211 D 1246995 CDS YP_008736010.1 556567585 17445358 5066503..5067366 1 NC_022657.1 COG3173 Predicted aminoglycoside phosphotransferase; aminoglycoside phosphotransferase 5067366 17445358 AFR_23435 Actinoplanes friuliensis DSM 7358 aminoglycoside phosphotransferase YP_008736010.1 5066503 D 1246995 CDS YP_008736011.1 556567586 17445359 5067368..5067706 1 NC_022657.1 hypothetical protein 5067706 17445359 AFR_23440 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736011.1 5067368 D 1246995 CDS YP_008736012.1 556567587 17445360 complement(5067680..5069005) 1 NC_022657.1 myeloperoxidase, thyroid peroxidase-like protein 5069005 17445360 AFR_23445 Actinoplanes friuliensis DSM 7358 myeloperoxidase, thyroid peroxidase-like protein YP_008736012.1 5067680 R 1246995 CDS YP_008736013.1 556567588 17445361 5069133..5070020 1 NC_022657.1 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; ECF subfamily RNA polymerase sigma-24 factor 5070020 17445361 AFR_23450 Actinoplanes friuliensis DSM 7358 ECF subfamily RNA polymerase sigma-24 factor YP_008736013.1 5069133 D 1246995 CDS YP_008736014.1 556567589 17445362 5070086..5071447 1 NC_022657.1 COG1252 NADH dehydrogenase, FAD-containing subunit; FAD-dependent pyridine nucleotide-disulfide oxidoreductase 5071447 17445362 AFR_23455 Actinoplanes friuliensis DSM 7358 FAD-dependent pyridine nucleotide-disulfide oxidoreductase YP_008736014.1 5070086 D 1246995 CDS YP_008736015.1 556567590 17445363 complement(5071410..5072144) 1 NC_022657.1 COG0702 Predicted nucleoside-diphosphate-sugar epimerases; hypothetical protein 5072144 17445363 AFR_23460 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736015.1 5071410 R 1246995 CDS YP_008736016.1 556567591 17445364 5072276..5072974 1 NC_022657.1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; winged helix family two component transcriptional regulator 5072974 17445364 AFR_23465 Actinoplanes friuliensis DSM 7358 winged helix family two component transcriptional regulator YP_008736016.1 5072276 D 1246995 CDS YP_008736017.1 556567592 17445365 5072971..5074002 1 NC_022657.1 COG5002 Signal transduction histidine kinase; ATP-binding region ATPase domain-containing protein 5074002 17445365 AFR_23470 Actinoplanes friuliensis DSM 7358 ATP-binding region ATPase domain-containing protein YP_008736017.1 5072971 D 1246995 CDS YP_008736018.1 556567593 17445366 complement(5073992..5074396) 1 NC_022657.1 hypothetical protein 5074396 17445366 AFR_23475 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736018.1 5073992 R 1246995 CDS YP_008736019.1 556567594 17445367 complement(5074393..5075628) 1 NC_022657.1 COG2041 Sulfite oxidase and related enzymes; oxidoreductase molybdopterin binding protein 5075628 17445367 AFR_23480 Actinoplanes friuliensis DSM 7358 oxidoreductase molybdopterin binding protein YP_008736019.1 5074393 R 1246995 CDS YP_008736020.1 556567595 17445368 complement(5075601..5076236) 1 NC_022657.1 COG0500 SAM-dependent methyltransferases; 3-demethylubiquinone-9 3-methyltransferase 5076236 17445368 AFR_23485 Actinoplanes friuliensis DSM 7358 3-demethylubiquinone-9 3-methyltransferase YP_008736020.1 5075601 R 1246995 CDS YP_008736021.1 556567596 17445369 complement(5076233..5076838) 1 NC_022657.1 COG3222 Uncharacterized protein conserved in bacteria; hypothetical protein 5076838 17445369 AFR_23490 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736021.1 5076233 R 1246995 CDS YP_008736022.1 556567597 17445370 complement(5076835..5077527) 1 NC_022657.1 COG0463 Glycosyltransferases involved in cell wall biogenesis; family 2 glycosyl transferase 5077527 17445370 AFR_23495 Actinoplanes friuliensis DSM 7358 family 2 glycosyl transferase YP_008736022.1 5076835 R 1246995 CDS YP_008736023.1 556567598 17445371 5077652..5078680 1 NC_022657.1 COG0451 Nucleoside-diphosphate-sugar epimerases; epimerase 5078680 17445371 AFR_23500 Actinoplanes friuliensis DSM 7358 epimerase YP_008736023.1 5077652 D 1246995 CDS YP_008736024.1 556567599 17445372 5078677..5079978 1 NC_022657.1 hypothetical protein 5079978 17445372 AFR_23505 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736024.1 5078677 D 1246995 CDS YP_008736025.1 556567600 17445373 5080087..5081691 1 NC_022657.1 hypothetical protein 5081691 17445373 AFR_23510 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736025.1 5080087 D 1246995 CDS YP_008736026.1 556567601 17445374 complement(5081675..5082118) 1 NC_022657.1 COG3832 Uncharacterized conserved protein; activator of Hsp90 ATPase 1 family protein 5082118 17445374 AFR_23515 Actinoplanes friuliensis DSM 7358 activator of Hsp90 ATPase 1 family protein YP_008736026.1 5081675 R 1246995 CDS YP_008736027.1 556567602 17445375 complement(5082134..5082475) 1 NC_022657.1 COG0640 Predicted transcriptional regulators; ArsR family transcriptional regulator 5082475 17445375 AFR_23520 Actinoplanes friuliensis DSM 7358 ArsR family transcriptional regulator YP_008736027.1 5082134 R 1246995 CDS YP_008736028.1 556567603 17445376 complement(5082472..5082933) 1 NC_022657.1 COG3832 Uncharacterized conserved protein; activator of Hsp90 ATPase 1 family protein 5082933 17445376 AFR_23525 Actinoplanes friuliensis DSM 7358 activator of Hsp90 ATPase 1 family protein YP_008736028.1 5082472 R 1246995 CDS YP_008736029.1 556567604 17445377 complement(5083048..5083464) 1 NC_022657.1 COG0517 FOG: CBS domain; hypothetical protein 5083464 17445377 AFR_23530 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736029.1 5083048 R 1246995 CDS YP_008736030.1 556567605 17445378 5083597..5084436 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); hypothetical protein 5084436 17445378 AFR_23535 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736030.1 5083597 D 1246995 CDS YP_008736031.1 556567606 17445379 complement(5084385..5085575) 1 NC_022657.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); epoxide hydrolase domain-containing protein 5085575 17445379 AFR_23540 Actinoplanes friuliensis DSM 7358 epoxide hydrolase domain-containing protein YP_008736031.1 5084385 R 1246995 CDS YP_008736032.1 556567607 17445380 complement(5085572..5086171) 1 NC_022657.1 COG1309 Transcriptional regulator; putative transcriptional regulator, TetR family protein 5086171 17445380 AFR_23545 Actinoplanes friuliensis DSM 7358 putative transcriptional regulator, TetR family protein YP_008736032.1 5085572 R 1246995 CDS YP_008736033.1 556567608 17445381 5086274..5087386 1 NC_022657.1 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases; fumarate reductase/succinate dehydrogenase flavoprotein domain-containing protein 5087386 17445381 AFR_23550 Actinoplanes friuliensis DSM 7358 fumarate reductase/succinate dehydrogenase flavoprotein domain-containing protein YP_008736033.1 5086274 D 1246995 CDS YP_008736034.1 556567609 17445382 complement(5087404..5088234) 1 NC_022657.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); alpha/beta hydrolase 5088234 17445382 AFR_23555 Actinoplanes friuliensis DSM 7358 alpha/beta hydrolase YP_008736034.1 5087404 R 1246995 CDS YP_008736035.1 556567610 17445383 5088332..5089108 1 NC_022657.1 COG2273 Beta-glucanase/Beta-glucan synthetase; glycoside hydrolase family protein 5089108 17445383 AFR_23560 Actinoplanes friuliensis DSM 7358 glycoside hydrolase family protein YP_008736035.1 5088332 D 1246995 CDS YP_008736036.1 556567611 17445384 5089154..5090131 1 NC_022657.1 COG1619 Uncharacterized proteins, homologs of microcin C7 resistance protein MccF; microcin C7 self-immunity protein MccF 5090131 17445384 AFR_23565 Actinoplanes friuliensis DSM 7358 microcin C7 self-immunity protein MccF YP_008736036.1 5089154 D 1246995 CDS YP_008736037.1 556567612 17445385 5091318..5092460 1 NC_022657.1 COG2826 Transposase and inactivated derivatives, IS30 family; Transposase for insertion sequence element IS1086 5092460 17445385 AFR_23580 Actinoplanes friuliensis DSM 7358 Transposase for insertion sequence element IS1086 YP_008736037.1 5091318 D 1246995 CDS YP_008736038.1 556567613 17445386 complement(5092702..5093955) 1 NC_022657.1 COG5659 FOG: Transposase; putative transposase 5093955 17445386 AFR_23585 Actinoplanes friuliensis DSM 7358 putative transposase YP_008736038.1 5092702 R 1246995 CDS YP_008736039.1 556567614 17445387 5094037..5094222 1 NC_022657.1 hypothetical protein 5094222 17445387 AFR_23590 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736039.1 5094037 D 1246995 CDS YP_008736040.1 556567615 17445388 5094354..5095169 1 NC_022657.1 COG0726 Predicted xylanase/chitin deacetylase; polysaccharide deacetylase 5095169 17445388 AFR_23595 Actinoplanes friuliensis DSM 7358 polysaccharide deacetylase YP_008736040.1 5094354 D 1246995 CDS YP_008736041.1 556567616 17445389 5095184..5096194 1 NC_022657.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); LuxR family transcriptional regulator 5096194 17445389 AFR_23600 Actinoplanes friuliensis DSM 7358 LuxR family transcriptional regulator YP_008736041.1 5095184 D 1246995 CDS YP_008736042.1 556567617 17445390 5096239..5096886 1 NC_022657.1 COG0500 SAM-dependent methyltransferases; type 11 methyltransferase 5096886 17445390 AFR_23605 Actinoplanes friuliensis DSM 7358 type 11 methyltransferase YP_008736042.1 5096239 D 1246995 CDS YP_008736043.1 556567618 17445391 5096932..5097327 1 NC_022657.1 hypothetical protein 5097327 17445391 AFR_23610 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736043.1 5096932 D 1246995 CDS YP_008736044.1 556567619 17445392 complement(5097375..5098430) 1 NC_022657.1 COG0614 ABC-type Fe3+-hydroxamate transport system, periplasmic component; periplasmic binding protein 5098430 17445392 AFR_23615 Actinoplanes friuliensis DSM 7358 periplasmic binding protein YP_008736044.1 5097375 R 1246995 CDS YP_008736045.1 556567620 17445393 5098532..5099599 1 NC_022657.1 COG0609 ABC-type Fe3+-siderophore transport system, permease component; ABC-type Fe3+-siderophore transport system, permease component 5099599 17445393 AFR_23620 Actinoplanes friuliensis DSM 7358 ABC-type Fe3+-siderophore transport system, permease component YP_008736045.1 5098532 D 1246995 CDS YP_008736046.1 556567621 17445394 5099596..5100636 1 NC_022657.1 COG4779 ABC-type enterobactin transport system, permease component; ABC-type enterobactin transport system, permease component 5100636 17445394 AFR_23625 Actinoplanes friuliensis DSM 7358 ABC-type enterobactin transport system, permease component YP_008736046.1 5099596 D 1246995 CDS YP_008736047.1 556567622 17445395 5100647..5101480 1 NC_022657.1 COG1120 ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components; ABC transporter 5101480 17445395 AFR_23630 Actinoplanes friuliensis DSM 7358 ABC transporter YP_008736047.1 5100647 D 1246995 CDS YP_008736048.1 556567623 17445396 5101477..5103159 1 NC_022657.1 COG1132 ABC-type multidrug transport system, ATPase and permease components; lipid ABC transporter ATPase/inner membrane protein 5103159 17445396 AFR_23635 Actinoplanes friuliensis DSM 7358 lipid ABC transporter ATPase/inner membrane protein YP_008736048.1 5101477 D 1246995 CDS YP_008736049.1 556567624 17445397 5103156..5104877 1 NC_022657.1 COG1132 ABC-type multidrug transport system, ATPase and permease components; multidrug ABC transporter ATPase/permease-like protein 5104877 17445397 AFR_23640 Actinoplanes friuliensis DSM 7358 multidrug ABC transporter ATPase/permease-like protein YP_008736049.1 5103156 D 1246995 CDS YP_008736050.1 556567625 17445398 complement(5104874..5105941) 1 NC_022657.1 COG0500 SAM-dependent methyltransferases; type 12 methyltransferase 5105941 17445398 AFR_23645 Actinoplanes friuliensis DSM 7358 type 12 methyltransferase YP_008736050.1 5104874 R 1246995 CDS YP_008736051.1 556567626 17445399 5106031..5106969 1 NC_022657.1 COG0583 Transcriptional regulator; LysR family transcriptional regulator 5106969 17445399 AFR_23650 Actinoplanes friuliensis DSM 7358 LysR family transcriptional regulator YP_008736051.1 5106031 D 1246995 CDS YP_008736052.1 556567627 17445400 complement(5106929..5107813) 1 NC_022657.1 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases; luciferase-like monooxygenase 5107813 17445400 AFR_23655 Actinoplanes friuliensis DSM 7358 luciferase-like monooxygenase YP_008736052.1 5106929 R 1246995 CDS YP_008736053.1 556567628 17445401 complement(5107835..5108239) 1 NC_022657.1 hypothetical protein 5108239 17445401 AFR_23660 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736053.1 5107835 R 1246995 CDS YP_008736054.1 556567629 17445402 complement(5108244..5108450) 1 NC_022657.1 COG3251 Uncharacterized protein conserved in bacteria; hypothetical protein 5108450 17445402 AFR_23665 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736054.1 5108244 R 1246995 CDS YP_008736055.1 556567630 17445403 complement(5108450..5119195) 1 NC_022657.1 COG1020 Non-ribosomal peptide synthetase modules and related proteins; non-ribosomal peptide synthetase-like protein 5119195 17445403 AFR_23670 Actinoplanes friuliensis DSM 7358 non-ribosomal peptide synthetase-like protein YP_008736055.1 5108450 R 1246995 CDS YP_008736056.1 556567631 17445404 complement(5119192..5129568) 1 NC_022657.1 COG1020 Non-ribosomal peptide synthetase modules and related proteins; amino acid adenylation protein 5129568 17445404 AFR_23675 Actinoplanes friuliensis DSM 7358 amino acid adenylation protein YP_008736056.1 5119192 R 1246995 CDS YP_008736057.1 556567632 17445405 complement(5129565..5133989) 1 NC_022657.1 COG1020 Non-ribosomal peptide synthetase modules and related proteins; non-ribosomal peptide synthetase-like protein 5133989 17445405 AFR_23680 Actinoplanes friuliensis DSM 7358 non-ribosomal peptide synthetase-like protein YP_008736057.1 5129565 R 1246995 CDS YP_008736058.1 556567633 17445406 complement(5134096..5135619) 1 NC_022657.1 COG2072 Predicted flavoprotein involved in K+ transport; flavin-containing monooxygenase 5135619 17445406 AFR_23685 Actinoplanes friuliensis DSM 7358 flavin-containing monooxygenase YP_008736058.1 5134096 R 1246995 CDS YP_008736059.1 556567634 17445407 complement(5135622..5135873) 1 NC_022657.1 COG1917 Uncharacterized conserved protein, contains double-stranded beta-helix domain; hypothetical protein 5135873 17445407 AFR_23690 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736059.1 5135622 R 1246995 CDS YP_008736060.1 556567635 17445408 complement(5136165..5136956) 1 NC_022657.1 COG1414 Transcriptional regulator; IclR family transcriptional regulator 5136956 17445408 AFR_23695 Actinoplanes friuliensis DSM 7358 IclR family transcriptional regulator YP_008736060.1 5136165 R 1246995 CDS YP_008736061.1 556567636 17445409 5137113..5137799 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); short chain dehydrogenase 5137799 17445409 AFR_23700 Actinoplanes friuliensis DSM 7358 short chain dehydrogenase YP_008736061.1 5137113 D 1246995 CDS YP_008736062.1 556567637 17445410 5137799..5138302 1 NC_022657.1 COG3435 Gentisate 1,2-dioxygenase; cupin 2 domain-containing protein 5138302 17445410 AFR_23705 Actinoplanes friuliensis DSM 7358 cupin 2 domain-containing protein YP_008736062.1 5137799 D 1246995 CDS YP_008736063.1 556567638 17445411 5138299..5139174 1 NC_022657.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); 2-hydroxy-6-ketonona-2,4-dienedioic acid hydrolase 5139174 17445411 AFR_23710 Actinoplanes friuliensis DSM 7358 2-hydroxy-6-ketonona-2,4-dienedioic acid hydrolase YP_008736063.1 5138299 D 1246995 CDS YP_008736064.1 556567639 17445412 5139171..5140106 1 NC_022657.1 3-(2,3-dihydroxyphenyl)propionate dioxygenase 5140106 mhpB 17445412 mhpB Actinoplanes friuliensis DSM 7358 3-(2,3-dihydroxyphenyl)propionate dioxygenase YP_008736064.1 5139171 D 1246995 CDS YP_008736065.1 556567640 17445413 complement(5140043..5140990) 1 NC_022657.1 COG0583 Transcriptional regulator; LysR family transcriptional regulator 5140990 17445413 AFR_23720 Actinoplanes friuliensis DSM 7358 LysR family transcriptional regulator YP_008736065.1 5140043 R 1246995 CDS YP_008736066.1 556567641 17445414 5140305..5141015 1 NC_022657.1 hypothetical protein 5141015 17445414 AFR_23725 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736066.1 5140305 D 1246995 CDS YP_008736067.1 556567642 17445415 5141074..5142405 1 NC_022657.1 COG0160 4-aminobutyrate aminotransferase and related aminotransferases; 2,2-dialkylglycine decarboxylase 5142405 17445415 AFR_23730 Actinoplanes friuliensis DSM 7358 2,2-dialkylglycine decarboxylase YP_008736067.1 5141074 D 1246995 CDS YP_008736068.1 556567643 17445416 5142402..5143232 1 NC_022657.1 COG0451 Nucleoside-diphosphate-sugar epimerases; NAD-dependent epimerase/dehydratase 5143232 17445416 AFR_23735 Actinoplanes friuliensis DSM 7358 NAD-dependent epimerase/dehydratase YP_008736068.1 5142402 D 1246995 CDS YP_008736069.1 556567644 17445417 complement(5143215..5143580) 1 NC_022657.1 hypothetical protein 5143580 17445417 AFR_23740 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736069.1 5143215 R 1246995 CDS YP_008736070.1 556567645 17445418 complement(5143627..5144637) 1 NC_022657.1 COG0119 Isopropylmalate/homocitrate/citramalate synthases; 4-hyroxy-2-oxovalerate/4-hydroxy-2-oxopentanoic acid aldolase 5144637 17445418 AFR_23745 Actinoplanes friuliensis DSM 7358 4-hyroxy-2-oxovalerate/4-hydroxy-2-oxopentanoic acid aldolase YP_008736070.1 5143627 R 1246995 CDS YP_008736071.1 556567646 17445419 complement(5144634..5145554) 1 NC_022657.1 COG4569 Acetaldehyde dehydrogenase (acetylating); acetaldehyde dehydrogenase 5145554 17445419 AFR_23750 Actinoplanes friuliensis DSM 7358 acetaldehyde dehydrogenase YP_008736071.1 5144634 R 1246995 CDS YP_008736072.1 556567647 17445420 complement(5145551..5146315) 1 NC_022657.1 COG3971 2-keto-4-pentenoate hydratase; 2-keto-4-pentenoate hydratase 5146315 17445420 AFR_23755 Actinoplanes friuliensis DSM 7358 2-keto-4-pentenoate hydratase YP_008736072.1 5145551 R 1246995 CDS YP_008736073.1 556567648 17445421 complement(5146346..5147098) 1 NC_022657.1 COG1414 Transcriptional regulator; putative IclR family transcriptional regulator 5147098 17445421 AFR_23760 Actinoplanes friuliensis DSM 7358 putative IclR family transcriptional regulator YP_008736073.1 5146346 R 1246995 CDS YP_008736074.1 556567649 17445422 complement(5148044..5148775) 1 NC_022657.1 hypothetical protein 5148775 17445422 AFR_23765 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736074.1 5148044 R 1246995 CDS YP_008736075.1 556567650 17445423 5148861..5149382 1 NC_022657.1 hypothetical protein 5149382 17445423 AFR_23770 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736075.1 5148861 D 1246995 CDS YP_008736076.1 556567651 17445424 complement(5149357..5150208) 1 NC_022657.1 hypothetical protein 5150208 17445424 AFR_23775 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736076.1 5149357 R 1246995 CDS YP_008736077.1 556567652 17445425 complement(5150263..5150520) 1 NC_022657.1 hypothetical protein 5150520 17445425 AFR_23780 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736077.1 5150263 R 1246995 CDS YP_008736078.1 556567653 17445426 5150709..5151521 1 NC_022657.1 hypothetical protein 5151521 17445426 AFR_23785 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736078.1 5150709 D 1246995 CDS YP_008736079.1 556567654 17445427 5151570..5152004 1 NC_022657.1 hypothetical protein 5152004 17445427 AFR_23790 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736079.1 5151570 D 1246995 CDS YP_008736080.1 556567655 17445428 complement(5151980..5152618) 1 NC_022657.1 COG1072 Panthothenate kinase; fructose transport system kinase 5152618 17445428 AFR_23795 Actinoplanes friuliensis DSM 7358 fructose transport system kinase YP_008736080.1 5151980 R 1246995 CDS YP_008736081.1 556567656 17445429 complement(5152615..5153265) 1 NC_022657.1 COG0176 Transaldolase; transaldolase 5153265 17445429 AFR_23800 Actinoplanes friuliensis DSM 7358 transaldolase YP_008736081.1 5152615 R 1246995 CDS YP_008736082.1 556567657 17445430 complement(5153344..5154189) 1 NC_022657.1 COG0702 Predicted nucleoside-diphosphate-sugar epimerases; nucleotide-diphosphate-sugar epimerase/NmrA family protein 5154189 17445430 AFR_23805 Actinoplanes friuliensis DSM 7358 nucleotide-diphosphate-sugar epimerase/NmrA family protein YP_008736082.1 5153344 R 1246995 CDS YP_008736083.1 556567658 17445431 5154276..5154962 1 NC_022657.1 COG1309 Transcriptional regulator; TetR family transcriptional regulator 5154962 17445431 AFR_23810 Actinoplanes friuliensis DSM 7358 TetR family transcriptional regulator YP_008736083.1 5154276 D 1246995 CDS YP_008736084.1 556567659 17445432 5154998..5155282 1 NC_022657.1 hypothetical protein 5155282 17445432 AFR_23815 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736084.1 5154998 D 1246995 CDS YP_008736085.1 556567660 17445433 5155307..5156419 1 NC_022657.1 hypothetical protein 5156419 17445433 AFR_23820 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736085.1 5155307 D 1246995 CDS YP_008736086.1 556567661 17445434 5156421..5156714 1 NC_022657.1 hypothetical protein 5156714 17445434 AFR_23825 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736086.1 5156421 D 1246995 CDS YP_008736087.1 556567662 17445435 5156751..5160206 1 NC_022657.1 laminin G sub domain 2 5160206 17445435 AFR_23830 Actinoplanes friuliensis DSM 7358 laminin G sub domain 2 YP_008736087.1 5156751 D 1246995 CDS YP_008736088.1 556567663 17445436 complement(5160190..5161608) 1 NC_022657.1 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs; GntR family transcriptional regulator 5161608 17445436 AFR_23835 Actinoplanes friuliensis DSM 7358 GntR family transcriptional regulator YP_008736088.1 5160190 R 1246995 CDS YP_008736089.1 556567664 17445437 5161694..5162590 1 NC_022657.1 COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily; hypothetical protein 5162590 17445437 AFR_23840 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736089.1 5161694 D 1246995 CDS YP_008736090.1 556567665 17445438 5162722..5163072 1 NC_022657.1 Protein lsr2 5163072 17445438 AFR_23845 Actinoplanes friuliensis DSM 7358 Protein lsr2 YP_008736090.1 5162722 D 1246995 CDS YP_008736091.1 556567666 17445439 5163176..5163886 1 NC_022657.1 hypothetical protein 5163886 17445439 AFR_23850 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736091.1 5163176 D 1246995 CDS YP_008736092.1 556567667 17445440 5163883..5165073 1 NC_022657.1 major facilitator superfamily protein 5165073 17445440 AFR_23855 Actinoplanes friuliensis DSM 7358 major facilitator superfamily protein YP_008736092.1 5163883 D 1246995 CDS YP_008736093.1 556567668 17445441 5165130..5165933 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); putative short-chain dehydrogenase 5165933 17445441 AFR_23860 Actinoplanes friuliensis DSM 7358 putative short-chain dehydrogenase YP_008736093.1 5165130 D 1246995 CDS YP_008736094.1 556567669 17445442 complement(5165983..5167035) 1 NC_022657.1 hypothetical protein 5167035 17445442 AFR_23865 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736094.1 5165983 R 1246995 CDS YP_008736095.1 556567670 17445443 complement(5167032..5167538) 1 NC_022657.1 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; RNA polymerase sigma factor, sigma-70 family/RNA polymerase sigma-70 factor, sigma-E family protein 5167538 17445443 AFR_23870 Actinoplanes friuliensis DSM 7358 RNA polymerase sigma factor, sigma-70 family/RNA polymerase sigma-70 factor, sigma-E family protein YP_008736095.1 5167032 R 1246995 CDS YP_008736096.1 556567671 17445444 5167981..5168415 1 NC_022657.1 hypothetical protein 5168415 17445444 AFR_23875 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736096.1 5167981 D 1246995 CDS YP_008736097.1 556567672 17445445 complement(5168422..5169444) 1 NC_022657.1 hypothetical protein 5169444 17445445 AFR_23880 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736097.1 5168422 R 1246995 CDS YP_008736098.1 556567673 17445446 complement(5169441..5169953) 1 NC_022657.1 hypothetical protein 5169953 17445446 AFR_23885 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736098.1 5169441 R 1246995 CDS YP_008736099.1 556567674 17445447 complement(5169937..5170530) 1 NC_022657.1 putative pyridoxamine 5'-phosphate oxidase-related protein 5170530 17445447 AFR_23890 Actinoplanes friuliensis DSM 7358 putative pyridoxamine 5'-phosphate oxidase-related protein YP_008736099.1 5169937 R 1246995 CDS YP_008736100.1 556567675 17445448 complement(5170569..5170994) 1 NC_022657.1 hypothetical protein 5170994 17445448 AFR_23895 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736100.1 5170569 R 1246995 CDS YP_008736101.1 556567676 17445449 complement(5171039..5171680) 1 NC_022657.1 hypothetical protein 5171680 17445449 AFR_23900 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736101.1 5171039 R 1246995 CDS YP_008736102.1 556567677 17445450 complement(5171734..5172333) 1 NC_022657.1 hypothetical protein 5172333 17445450 AFR_23905 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736102.1 5171734 R 1246995 CDS YP_008736103.1 556567678 17445451 complement(5172416..5173468) 1 NC_022657.1 hypothetical protein 5173468 17445451 AFR_23910 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736103.1 5172416 R 1246995 CDS YP_008736104.1 556567679 17445452 complement(5173465..5174031) 1 NC_022657.1 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; ECF subfamily RNA polymerase sigma-24 subunit 5174031 17445452 AFR_23915 Actinoplanes friuliensis DSM 7358 ECF subfamily RNA polymerase sigma-24 subunit YP_008736104.1 5173465 R 1246995 CDS YP_008736105.1 556567680 17445453 5174168..5174575 1 NC_022657.1 COG3795 Uncharacterized protein conserved in bacteria; hypothetical protein 5174575 17445453 AFR_23920 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736105.1 5174168 D 1246995 CDS YP_008736106.1 556567681 17445454 5174584..5175723 1 NC_022657.1 COG4941 Predicted RNA polymerase sigma factor containing a TPR repeat domain; ECF subfamily RNA polymerase sigma factor 5175723 17445454 AFR_23925 Actinoplanes friuliensis DSM 7358 ECF subfamily RNA polymerase sigma factor YP_008736106.1 5174584 D 1246995 CDS YP_008736107.1 556567682 17445455 complement(5176083..5176589) 1 NC_022657.1 COG1846 Transcriptional regulators; regulatory protein MarR 5176589 17445455 AFR_23930 Actinoplanes friuliensis DSM 7358 regulatory protein MarR YP_008736107.1 5176083 R 1246995 CDS YP_008736108.1 556567683 17445456 5176626..5177648 1 NC_022657.1 COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily; hypothetical protein 5177648 17445456 AFR_23935 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736108.1 5176626 D 1246995 CDS YP_008736109.1 556567684 17445457 5177688..5178674 1 NC_022657.1 COG0861 Membrane protein TerC, possibly involved in tellurium resistance; integral membrane protein TerC 5178674 17445457 AFR_23940 Actinoplanes friuliensis DSM 7358 integral membrane protein TerC YP_008736109.1 5177688 D 1246995 CDS YP_008736110.1 556567685 17445458 complement(5178667..5179548) 1 NC_022657.1 COG0702 Predicted nucleoside-diphosphate-sugar epimerases; NmrA family protein 5179548 17445458 AFR_23945 Actinoplanes friuliensis DSM 7358 NmrA family protein YP_008736110.1 5178667 R 1246995 CDS YP_008736111.1 556567686 17445459 5179618..5180511 1 NC_022657.1 COG0583 Transcriptional regulator; LysR family transcriptional regulator 5180511 17445459 AFR_23950 Actinoplanes friuliensis DSM 7358 LysR family transcriptional regulator YP_008736111.1 5179618 D 1246995 CDS YP_008736112.1 556567687 17445460 5180574..5180822 1 NC_022657.1 hypothetical protein 5180822 17445460 AFR_23955 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736112.1 5180574 D 1246995 CDS YP_008736113.1 556567688 17445461 complement(5180855..5181913) 1 NC_022657.1 hypothetical protein 5181913 17445461 AFR_23960 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736113.1 5180855 R 1246995 CDS YP_008736114.1 556567689 17445462 5182173..5183537 1 NC_022657.1 COG1653 ABC-type sugar transport system, periplasmic component; putative ABC transporter substrate-binding protein 5183537 17445462 AFR_23965 Actinoplanes friuliensis DSM 7358 putative ABC transporter substrate-binding protein YP_008736114.1 5182173 D 1246995 CDS YP_008736115.1 556567690 17445463 5183613..5184596 1 NC_022657.1 COG1175 ABC-type sugar transport systems, permease components; ABC transporter permease 5184596 17445463 AFR_23970 Actinoplanes friuliensis DSM 7358 ABC transporter permease YP_008736115.1 5183613 D 1246995 CDS YP_008736116.1 556567691 17445464 5184614..5185507 1 NC_022657.1 COG0395 ABC-type sugar transport system, permease component; binding-protein-dependent transport systems inner membrane component 5185507 17445464 AFR_23975 Actinoplanes friuliensis DSM 7358 binding-protein-dependent transport systems inner membrane component YP_008736116.1 5184614 D 1246995 CDS YP_008736117.1 556567692 17445465 complement(5185561..5187987) 1 NC_022657.1 COG0058 Glucan phosphorylase; starch phosphorylase 5187987 17445465 AFR_23980 Actinoplanes friuliensis DSM 7358 starch phosphorylase YP_008736117.1 5185561 R 1246995 CDS YP_008736118.1 556567693 17445466 complement(5188107..5188676) 1 NC_022657.1 hypothetical protein 5188676 17445466 AFR_23985 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736118.1 5188107 R 1246995 CDS YP_008736119.1 556567694 17445467 5188792..5189163 1 NC_022657.1 hypothetical protein 5189163 17445467 AFR_23990 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736119.1 5188792 D 1246995 CDS YP_008736120.1 556567695 17445468 complement(5189168..5191060) 1 NC_022657.1 COG0642 Signal transduction histidine kinase; putative two-component system sensor kinase 5191060 17445468 AFR_23995 Actinoplanes friuliensis DSM 7358 putative two-component system sensor kinase YP_008736120.1 5189168 R 1246995 CDS YP_008736121.1 556567696 17445469 complement(5191095..5192705) 1 NC_022657.1 COG2203 FOG: GAF domain; Phytochrome A type 3 5192705 17445469 AFR_24000 Actinoplanes friuliensis DSM 7358 Phytochrome A type 3 YP_008736121.1 5191095 R 1246995 CDS YP_008736122.1 556567697 17445470 5193141..5193770 1 NC_022657.1 cholesterol esterase 5193770 17445470 AFR_24005 Actinoplanes friuliensis DSM 7358 cholesterol esterase YP_008736122.1 5193141 D 1246995 CDS YP_008736123.1 556567698 17445471 5194321..5195439 1 NC_022657.1 Otogelin 5195439 17445471 AFR_24010 Actinoplanes friuliensis DSM 7358 Otogelin YP_008736123.1 5194321 D 1246995 CDS YP_008736124.1 556567699 17445472 5195456..5196886 1 NC_022657.1 COG0778 Nitroreductase; hypothetical protein 5196886 17445472 AFR_24015 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736124.1 5195456 D 1246995 CDS YP_008736125.1 556567700 17445473 5196981..5199365 1 NC_022657.1 COG0178 Excinuclease ATPase subunit; UvrABC system protein A 5199365 17445473 AFR_24020 Actinoplanes friuliensis DSM 7358 UvrABC system protein A YP_008736125.1 5196981 D 1246995 CDS YP_008736126.1 556567701 17445474 complement(5199350..5199751) 1 NC_022657.1 DnaJ-like subfamily C member 28 protein 5199751 17445474 AFR_24025 Actinoplanes friuliensis DSM 7358 DnaJ-like subfamily C member 28 protein YP_008736126.1 5199350 R 1246995 CDS YP_008736127.1 556567702 17445475 complement(5199761..5200594) 1 NC_022657.1 COG2513 PEP phosphonomutase and related enzymes; PEP phosphonomutase 5200594 17445475 AFR_24030 Actinoplanes friuliensis DSM 7358 PEP phosphonomutase YP_008736127.1 5199761 R 1246995 CDS YP_008736128.1 556567703 17445476 5200593..5201513 1 NC_022657.1 COG0640 Predicted transcriptional regulators; transcription regulator ArsR 5201513 17445476 AFR_24035 Actinoplanes friuliensis DSM 7358 transcription regulator ArsR YP_008736128.1 5200593 D 1246995 CDS YP_008736129.1 556567704 17445477 complement(5201274..5201969) 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); short-chain dehydrogenase 5201969 17445477 AFR_24040 Actinoplanes friuliensis DSM 7358 short-chain dehydrogenase YP_008736129.1 5201274 R 1246995 CDS YP_008736130.1 556567705 17445478 5202072..5202893 1 NC_022657.1 COG1396 Predicted transcriptional regulators; XRE family transcriptional regulator 5202893 17445478 AFR_24045 Actinoplanes friuliensis DSM 7358 XRE family transcriptional regulator YP_008736130.1 5202072 D 1246995 CDS YP_008736131.1 556567706 17445479 complement(5202928..5203923) 1 NC_022657.1 hypothetical protein 5203923 17445479 AFR_24050 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736131.1 5202928 R 1246995 CDS YP_008736132.1 556567707 17445480 complement(5203920..5204648) 1 NC_022657.1 COG1131 ABC-type multidrug transport system, ATPase component; ABC transporter 5204648 17445480 AFR_24055 Actinoplanes friuliensis DSM 7358 ABC transporter YP_008736132.1 5203920 R 1246995 CDS YP_008736133.1 556567708 17445481 5204831..5205484 1 NC_022657.1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; two-component regulator CutR 5205484 17445481 AFR_24060 Actinoplanes friuliensis DSM 7358 two-component regulator CutR YP_008736133.1 5204831 D 1246995 CDS YP_008736134.1 556567709 17445482 5205486..5206580 1 NC_022657.1 COG0642 Signal transduction histidine kinase; histidine kinase 5206580 17445482 AFR_24065 Actinoplanes friuliensis DSM 7358 histidine kinase YP_008736134.1 5205486 D 1246995 CDS YP_008736135.1 556567710 17445483 5206672..5208885 1 NC_022657.1 COG5520 O-Glycosyl hydrolase; glucosylceramidase 5208885 17445483 AFR_24070 Actinoplanes friuliensis DSM 7358 glucosylceramidase YP_008736135.1 5206672 D 1246995 CDS YP_008736136.1 556567711 17445484 complement(5208928..5209878) 1 NC_022657.1 hypothetical protein 5209878 17445484 AFR_24075 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736136.1 5208928 R 1246995 CDS YP_008736137.1 556567712 17445485 complement(5209878..5210375) 1 NC_022657.1 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; putative RNA polymerase ECF-subfamily sigma factor 5210375 17445485 AFR_24080 Actinoplanes friuliensis DSM 7358 putative RNA polymerase ECF-subfamily sigma factor YP_008736137.1 5209878 R 1246995 CDS YP_008736138.1 556567713 17445486 complement(5210460..5211209) 1 NC_022657.1 COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases; AMP-dependent synthetase and ligase 5211209 17445486 AFR_24085 Actinoplanes friuliensis DSM 7358 AMP-dependent synthetase and ligase YP_008736138.1 5210460 R 1246995 CDS YP_008736139.1 556567714 17445487 complement(5211219..5212097) 1 NC_022657.1 COG1396 Predicted transcriptional regulators; putative DNA-binding protein 5212097 17445487 AFR_24090 Actinoplanes friuliensis DSM 7358 putative DNA-binding protein YP_008736139.1 5211219 R 1246995 CDS YP_008736140.1 556567715 17445488 complement(5212116..5212919) 1 NC_022657.1 hypothetical protein 5212919 17445488 AFR_24095 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736140.1 5212116 R 1246995 CDS YP_008736141.1 556567716 17445489 complement(5213014..5213769) 1 NC_022657.1 COG1349 Transcriptional regulators of sugar metabolism; DeoR family transcriptional regulator 5213769 17445489 AFR_24100 Actinoplanes friuliensis DSM 7358 DeoR family transcriptional regulator YP_008736141.1 5213014 R 1246995 CDS YP_008736142.1 556567717 17445490 5213835..5214194 1 NC_022657.1 hypothetical protein 5214194 17445490 AFR_24105 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736142.1 5213835 D 1246995 CDS YP_008736143.1 556567718 17445491 complement(5214531..5215004) 1 NC_022657.1 COG2606 Uncharacterized conserved protein; hypothetical protein 5215004 17445491 AFR_24110 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736143.1 5214531 R 1246995 CDS YP_008736144.1 556567719 17445492 5215095..5216906 1 NC_022657.1 COG0642 Signal transduction histidine kinase; histidine kinase 5216906 17445492 AFR_24115 Actinoplanes friuliensis DSM 7358 histidine kinase YP_008736144.1 5215095 D 1246995 CDS YP_008736145.1 556567720 17445493 complement(5216887..5218932) 1 NC_022657.1 COG1620 L-lactate permease; L-lactate permease 5218932 17445493 AFR_24120 Actinoplanes friuliensis DSM 7358 L-lactate permease YP_008736145.1 5216887 R 1246995 CDS YP_008736146.1 556567721 17445494 5219278..5219835 1 NC_022657.1 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; hypothetical protein 5219835 17445494 AFR_24125 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736146.1 5219278 D 1246995 CDS YP_008736147.1 556567722 17445495 complement(5220214..5221746) 1 NC_022657.1 COG0531 Amino acid transporters; Putrescine importer 5221746 17445495 AFR_24130 Actinoplanes friuliensis DSM 7358 Putrescine importer YP_008736147.1 5220214 R 1246995 CDS YP_008736148.1 556567723 17445496 complement(5221809..5222447) 1 NC_022657.1 COG0574 Phosphoenolpyruvate synthase/pyruvate phosphate dikinase; hypothetical protein 5222447 17445496 AFR_24135 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736148.1 5221809 R 1246995 CDS YP_008736149.1 556567724 17445497 5222654..5223502 1 NC_022657.1 putative DNA-binding protein 5223502 17445497 AFR_24140 Actinoplanes friuliensis DSM 7358 putative DNA-binding protein YP_008736149.1 5222654 D 1246995 CDS YP_008736150.1 556567725 17445498 5223604..5223819 1 NC_022657.1 hypothetical protein 5223819 17445498 AFR_24145 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736150.1 5223604 D 1246995 CDS YP_008736151.1 556567726 17445499 5224190..5225242 1 NC_022657.1 COG0019 Diaminopimelate decarboxylase; Orn/DAP/Arg decarboxylase family protein 5225242 17445499 AFR_24150 Actinoplanes friuliensis DSM 7358 Orn/DAP/Arg decarboxylase family protein YP_008736151.1 5224190 D 1246995 CDS YP_008736152.1 556567727 17445500 5225282..5225944 1 NC_022657.1 hypothetical protein 5225944 17445500 AFR_24155 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736152.1 5225282 D 1246995 CDS YP_008736153.1 556567728 17445501 complement(5225941..5226393) 1 NC_022657.1 hypothetical protein 5226393 17445501 AFR_24160 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736153.1 5225941 R 1246995 CDS YP_008736154.1 556567729 17445502 complement(5226469..5227557) 1 NC_022657.1 COG4213 ABC-type xylose transport system, periplasmic component; putative ABC transporter substrate-binding protein 5227557 17445502 AFR_24165 Actinoplanes friuliensis DSM 7358 putative ABC transporter substrate-binding protein YP_008736154.1 5226469 R 1246995 CDS YP_008736155.1 556567730 17445503 complement(5227647..5228453) 1 NC_022657.1 hypothetical protein 5228453 17445503 AFR_24170 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736155.1 5227647 R 1246995 CDS YP_008736156.1 556567731 17445504 5228564..5230870 1 NC_022657.1 COG2202 FOG: PAS/PAC domain; putative multi-sensor signal transduction histidine kinase 5230870 17445504 AFR_24175 Actinoplanes friuliensis DSM 7358 putative multi-sensor signal transduction histidine kinase YP_008736156.1 5228564 D 1246995 CDS YP_008736157.1 556567732 17445505 5230883..5231758 1 NC_022657.1 hypothetical protein 5231758 17445505 AFR_24180 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736157.1 5230883 D 1246995 CDS YP_008736158.1 556567733 17445506 complement(5231733..5232797) 1 NC_022657.1 COG3391 Uncharacterized conserved protein; hypothetical protein 5232797 17445506 AFR_24185 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736158.1 5231733 R 1246995 CDS YP_008736159.1 556567734 17445507 complement(5232845..5234797) 1 NC_022657.1 COG0366 Glycosidases; alpha amylase 5234797 17445507 AFR_24190 Actinoplanes friuliensis DSM 7358 alpha amylase YP_008736159.1 5232845 R 1246995 CDS YP_008736160.1 556567735 17445508 complement(5234897..5235550) 1 NC_022657.1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; putative two-component system response regulator 5235550 17445508 AFR_24195 Actinoplanes friuliensis DSM 7358 putative two-component system response regulator YP_008736160.1 5234897 R 1246995 CDS YP_008736161.1 556567736 17445509 complement(5235532..5236776) 1 NC_022657.1 COG4564 Signal transduction histidine kinase; integral membrane sensor signal transduction histidine kinase 5236776 17445509 AFR_24200 Actinoplanes friuliensis DSM 7358 integral membrane sensor signal transduction histidine kinase YP_008736161.1 5235532 R 1246995 CDS YP_008736162.1 556567737 17445510 5236911..5237651 1 NC_022657.1 COG1136 ABC-type antimicrobial peptide transport system, ATPase component; ABC transporter ATP-binding protein 5237651 17445510 AFR_24205 Actinoplanes friuliensis DSM 7358 ABC transporter ATP-binding protein YP_008736162.1 5236911 D 1246995 CDS YP_008736163.1 556567738 17445511 5237648..5239969 1 NC_022657.1 COG4591 ABC-type transport system, involved in lipoprotein release, permease component; ABC transporter permease 5239969 17445511 AFR_24210 Actinoplanes friuliensis DSM 7358 ABC transporter permease YP_008736163.1 5237648 D 1246995 CDS YP_008736164.1 556567739 17445512 5239966..5241642 1 NC_022657.1 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases; thioredoxin reductase 5241642 17445512 AFR_24215 Actinoplanes friuliensis DSM 7358 thioredoxin reductase YP_008736164.1 5239966 D 1246995 CDS YP_008736165.1 556567740 17445513 complement(5241645..5242211) 1 NC_022657.1 COG1309 Transcriptional regulator; regulatory protein TetR 5242211 17445513 AFR_24220 Actinoplanes friuliensis DSM 7358 regulatory protein TetR YP_008736165.1 5241645 R 1246995 CDS YP_008736166.1 556567741 17445514 5242293..5243183 1 NC_022657.1 COG0451 Nucleoside-diphosphate-sugar epimerases; NAD-dependent epimerase/dehydratase 5243183 17445514 AFR_24225 Actinoplanes friuliensis DSM 7358 NAD-dependent epimerase/dehydratase YP_008736166.1 5242293 D 1246995 CDS YP_008736167.1 556567742 17445515 complement(5243171..5244784) 1 NC_022657.1 COG1123 ATPase components of various ABC-type transport systems, contain duplicated ATPase; Ribose import ATP-binding protein rbsA 5244784 17445515 AFR_24230 Actinoplanes friuliensis DSM 7358 Ribose import ATP-binding protein rbsA YP_008736167.1 5243171 R 1246995 CDS YP_008736168.1 556567743 17445516 complement(5244781..5245770) 1 NC_022657.1 COG0601 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components; putative D,D-dipeptide transport system permease protein ddpB 5245770 17445516 AFR_24235 Actinoplanes friuliensis DSM 7358 putative D,D-dipeptide transport system permease protein ddpB YP_008736168.1 5244781 R 1246995 CDS YP_008736169.1 556567744 17445517 complement(5245767..5246651) 1 NC_022657.1 COG1173 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components; oligopeptide transport system permease AppC 5246651 17445517 AFR_24240 Actinoplanes friuliensis DSM 7358 oligopeptide transport system permease AppC YP_008736169.1 5245767 R 1246995 CDS YP_008736170.1 556567745 17445518 complement(5246648..5248327) 1 NC_022657.1 COG0747 ABC-type dipeptide transport system, periplasmic component; peptide/nickel transport system substrate-binding protein 5248327 17445518 AFR_24245 Actinoplanes friuliensis DSM 7358 peptide/nickel transport system substrate-binding protein YP_008736170.1 5246648 R 1246995 CDS YP_008736171.1 556567746 17445519 5248457..5249545 1 NC_022657.1 COG3572 Gamma-glutamylcysteine synthetase; glutamate/cysteine ligase 5249545 17445519 AFR_24250 Actinoplanes friuliensis DSM 7358 glutamate/cysteine ligase YP_008736171.1 5248457 D 1246995 CDS YP_008736172.1 556567747 17445520 5249632..5250906 1 NC_022657.1 COG3285 Predicted eukaryotic-type DNA primase; DNA ligase D 5250906 17445520 AFR_24255 Actinoplanes friuliensis DSM 7358 DNA ligase D YP_008736172.1 5249632 D 1246995 CDS YP_008736173.1 556567748 17445521 5252057..5252530 1 NC_022657.1 hypothetical protein 5252530 17445521 AFR_24270 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736173.1 5252057 D 1246995 CDS YP_008736174.1 556567749 17445522 5252527..5253234 1 NC_022657.1 ANTAR domain-containing protein 5253234 17445522 AFR_24275 Actinoplanes friuliensis DSM 7358 ANTAR domain-containing protein YP_008736174.1 5252527 D 1246995 CDS YP_008736175.1 556567750 17445523 complement(5253249..5254529) 1 NC_022657.1 COG2321 Predicted metalloprotease; zinc metallopeptidase 5254529 17445523 AFR_24280 Actinoplanes friuliensis DSM 7358 zinc metallopeptidase YP_008736175.1 5253249 R 1246995 CDS YP_008736176.1 556567751 17445524 complement(5254580..5254768) 1 NC_022657.1 hypothetical protein 5254768 17445524 AFR_24285 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736176.1 5254580 R 1246995 CDS YP_008736177.1 556567752 17445525 complement(5254842..5256020) 1 NC_022657.1 COG2208 Serine phosphatase RsbU, regulator of sigma subunit; putative magnesium/manganese-dependent protein phosphatase 5256020 17445525 AFR_24290 Actinoplanes friuliensis DSM 7358 putative magnesium/manganese-dependent protein phosphatase YP_008736177.1 5254842 R 1246995 CDS YP_008736178.1 556567753 17445526 5256156..5256581 1 NC_022657.1 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); hypothetical protein 5256581 17445526 AFR_24295 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736178.1 5256156 D 1246995 CDS YP_008736179.1 556567754 17445527 complement(5256597..5257031) 1 NC_022657.1 COG3920 Signal transduction histidine kinase; hypothetical protein 5257031 17445527 AFR_24300 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736179.1 5256597 R 1246995 CDS YP_008736180.1 556567755 17445528 5257112..5258089 1 NC_022657.1 COG2890 Methylase of polypeptide chain release factors; 50S ribosomal protein L11 methyltransferase 5258089 17445528 AFR_24305 Actinoplanes friuliensis DSM 7358 50S ribosomal protein L11 methyltransferase YP_008736180.1 5257112 D 1246995 CDS YP_008736181.1 556567756 17445529 5258086..5259180 1 NC_022657.1 COG2170 Uncharacterized conserved protein; glutamate--cysteine ligase gCS2 5259180 17445529 AFR_24310 Actinoplanes friuliensis DSM 7358 glutamate--cysteine ligase gCS2 YP_008736181.1 5258086 D 1246995 CDS YP_008736182.1 556567757 17445530 complement(5259234..5260406) 1 NC_022657.1 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases; alcohol dehydrogenase GroES domain protein 5260406 17445530 AFR_24315 Actinoplanes friuliensis DSM 7358 alcohol dehydrogenase GroES domain protein YP_008736182.1 5259234 R 1246995 CDS YP_008736183.1 556567758 17445531 complement(5260403..5260708) 1 NC_022657.1 hypothetical protein 5260708 17445531 AFR_24320 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736183.1 5260403 R 1246995 CDS YP_008736184.1 556567759 17445532 5260923..5261369 1 NC_022657.1 hypothetical protein 5261369 17445532 AFR_24325 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736184.1 5260923 D 1246995 CDS YP_008736185.1 556567760 17445533 5261640..5261843 1 NC_022657.1 hypothetical protein 5261843 17445533 AFR_24330 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736185.1 5261640 D 1246995 CDS YP_008736186.1 556567761 17445534 complement(5261854..5262441) 1 NC_022657.1 COG1309 Transcriptional regulator; transcriptional regulator 5262441 17445534 AFR_24335 Actinoplanes friuliensis DSM 7358 transcriptional regulator YP_008736186.1 5261854 R 1246995 CDS YP_008736187.1 556567762 17445535 5262579..5263400 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); short-chain dehydrogenase/reductase SDR 5263400 17445535 AFR_24340 Actinoplanes friuliensis DSM 7358 short-chain dehydrogenase/reductase SDR YP_008736187.1 5262579 D 1246995 CDS YP_008736188.1 556567763 17445536 complement(5263376..5263954) 1 NC_022657.1 COG2246 Predicted membrane protein; hypothetical protein 5263954 17445536 AFR_24345 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736188.1 5263376 R 1246995 CDS YP_008736189.1 556567764 17445537 complement(5263993..5265024) 1 NC_022657.1 COG1432 Uncharacterized conserved protein; hypothetical protein 5265024 17445537 AFR_24350 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736189.1 5263993 R 1246995 CDS YP_008736190.1 556567765 17445538 complement(5265034..5266296) 1 NC_022657.1 COG0477 Permeases of the major facilitator superfamily; major facilitator transporter 5266296 17445538 AFR_24355 Actinoplanes friuliensis DSM 7358 major facilitator transporter YP_008736190.1 5265034 R 1246995 CDS YP_008736191.1 556567766 17445539 complement(5266293..5266763) 1 NC_022657.1 COG1846 Transcriptional regulators; MarR family transcriptional regulator 5266763 17445539 AFR_24360 Actinoplanes friuliensis DSM 7358 MarR family transcriptional regulator YP_008736191.1 5266293 R 1246995 CDS YP_008736192.1 556567767 17445540 5266835..5267377 1 NC_022657.1 COG1309 Transcriptional regulator; bacterial regulatory s, tetR family protein 5267377 17445540 AFR_24365 Actinoplanes friuliensis DSM 7358 bacterial regulatory s, tetR family protein YP_008736192.1 5266835 D 1246995 CDS YP_008736193.1 556567768 17445541 5267459..5268475 1 NC_022657.1 COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases; alcohol dehydrogenase 5268475 17445541 AFR_24370 Actinoplanes friuliensis DSM 7358 alcohol dehydrogenase YP_008736193.1 5267459 D 1246995 CDS YP_008736194.1 556567769 17445542 5268503..5269423 1 NC_022657.1 COG0583 Transcriptional regulator; putative LysR-family transcriptional regulator 5269423 17445542 AFR_24375 Actinoplanes friuliensis DSM 7358 putative LysR-family transcriptional regulator YP_008736194.1 5268503 D 1246995 CDS YP_008736195.1 556567770 17445543 5269483..5270394 1 NC_022657.1 COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily; hypothetical protein 5270394 17445543 AFR_24380 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736195.1 5269483 D 1246995 CDS YP_008736196.1 556567771 17445544 complement(5270373..5271464) 1 NC_022657.1 COG3842 ABC-type spermidine/putrescine transport systems, ATPase components; ABC transporter 5271464 17445544 AFR_24385 Actinoplanes friuliensis DSM 7358 ABC transporter YP_008736196.1 5270373 R 1246995 CDS YP_008736197.1 556567772 17445545 complement(5271461..5273206) 1 NC_022657.1 COG1178 ABC-type Fe3+ transport system, permease component; binding-protein-dependent transport systems inner membrane component 5273206 17445545 AFR_24390 Actinoplanes friuliensis DSM 7358 binding-protein-dependent transport systems inner membrane component YP_008736197.1 5271461 R 1246995 CDS YP_008736198.1 556567773 17445546 complement(5273290..5274348) 1 NC_022657.1 COG1840 ABC-type Fe3+ transport system, periplasmic component; extracellular solute-binding protein family 1 protein 5274348 17445546 AFR_24395 Actinoplanes friuliensis DSM 7358 extracellular solute-binding protein family 1 protein YP_008736198.1 5273290 R 1246995 CDS YP_008736199.1 556567774 17445547 complement(5274468..5275175) 1 NC_022657.1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; winged helix family two component transcriptional regulator 5275175 17445547 AFR_24400 Actinoplanes friuliensis DSM 7358 winged helix family two component transcriptional regulator YP_008736199.1 5274468 R 1246995 CDS YP_008736200.1 556567775 17445548 complement(5275172..5276029) 1 NC_022657.1 COG0642 Signal transduction histidine kinase; histidine kinase 5276029 17445548 AFR_24405 Actinoplanes friuliensis DSM 7358 histidine kinase YP_008736200.1 5275172 R 1246995 CDS YP_008736201.1 556567776 17445549 complement(5276107..5276967) 1 NC_022657.1 COG2175 Probable taurine catabolism dioxygenase; putative taurine catabolism dioxygenase 5276967 17445549 AFR_24410 Actinoplanes friuliensis DSM 7358 putative taurine catabolism dioxygenase YP_008736201.1 5276107 R 1246995 CDS YP_008736202.1 556567777 17445550 complement(5276964..5277740) 1 NC_022657.1 COG1116 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component; putative ABC transporter ATP-binding protein 5277740 17445550 AFR_24415 Actinoplanes friuliensis DSM 7358 putative ABC transporter ATP-binding protein YP_008736202.1 5276964 R 1246995 CDS YP_008736203.1 556567778 17445551 complement(5277727..5278758) 1 NC_022657.1 COG4521 ABC-type taurine transport system, periplasmic component; putative ABC transporter substrate-binding protein 5278758 17445551 AFR_24420 Actinoplanes friuliensis DSM 7358 putative ABC transporter substrate-binding protein YP_008736203.1 5277727 R 1246995 CDS YP_008736204.1 556567779 17445552 complement(5278770..5279639) 1 NC_022657.1 COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component; ABC transporter permease 5279639 17445552 AFR_24425 Actinoplanes friuliensis DSM 7358 ABC transporter permease YP_008736204.1 5278770 R 1246995 CDS YP_008736205.1 556567780 17445553 complement(5279705..5280547) 1 NC_022657.1 COG0666 FOG: Ankyrin repeat; putative ankyrin repeat protein 5280547 17445553 AFR_24430 Actinoplanes friuliensis DSM 7358 putative ankyrin repeat protein YP_008736205.1 5279705 R 1246995 CDS YP_008736206.1 556567781 17445554 5280785..5281132 1 NC_022657.1 COG3795 Uncharacterized protein conserved in bacteria; hypothetical protein 5281132 17445554 AFR_24435 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736206.1 5280785 D 1246995 CDS YP_008736207.1 556567782 17445555 5281135..5282394 1 NC_022657.1 COG4941 Predicted RNA polymerase sigma factor containing a TPR repeat domain; RNA polymerase ECF-subfamily sigma factor 5282394 17445555 AFR_24440 Actinoplanes friuliensis DSM 7358 RNA polymerase ECF-subfamily sigma factor YP_008736207.1 5281135 D 1246995 CDS YP_008736208.1 556567783 17445556 5282639..5283439 1 NC_022657.1 COG0500 SAM-dependent methyltransferases; type 11 methyltransferase 5283439 17445556 AFR_24445 Actinoplanes friuliensis DSM 7358 type 11 methyltransferase YP_008736208.1 5282639 D 1246995 CDS YP_008736209.1 556567784 17445557 complement(5283384..5283995) 1 NC_022657.1 COG1225 Peroxiredoxin; Peroxiredoxin Q 5283995 17445557 AFR_24450 Actinoplanes friuliensis DSM 7358 Peroxiredoxin Q YP_008736209.1 5283384 R 1246995 CDS YP_008736210.1 556567785 17445558 complement(5284113..5284814) 1 NC_022657.1 hypothetical protein 5284814 17445558 AFR_24455 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736210.1 5284113 R 1246995 CDS YP_008736211.1 556567786 17445559 complement(5284772..5285116) 1 NC_022657.1 hypothetical protein 5285116 17445559 AFR_24460 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736211.1 5284772 R 1246995 CDS YP_008736212.1 556567787 17445560 5285221..5285712 1 NC_022657.1 COG0288 Carbonic anhydrase; carbonic anhydrase 5285712 17445560 AFR_24465 Actinoplanes friuliensis DSM 7358 carbonic anhydrase YP_008736212.1 5285221 D 1246995 CDS YP_008736213.1 556567788 17445561 complement(5285705..5287360) 1 NC_022657.1 COG3573 Predicted oxidoreductase; FAD-binding dehydrogenase 5287360 17445561 AFR_24470 Actinoplanes friuliensis DSM 7358 FAD-binding dehydrogenase YP_008736213.1 5285705 R 1246995 CDS YP_008736214.1 556567789 17445562 5287443..5288576 1 NC_022657.1 COG2508 Regulator of polyketide synthase expression; hypothetical protein 5288576 17445562 AFR_24475 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736214.1 5287443 D 1246995 CDS YP_008736215.1 556567790 17445563 complement(5288573..5289484) 1 NC_022657.1 COG1376 Uncharacterized protein conserved in bacteria; erfk/ybis/ycfs/ynhg family protein 5289484 17445563 AFR_24480 Actinoplanes friuliensis DSM 7358 erfk/ybis/ycfs/ynhg family protein YP_008736215.1 5288573 R 1246995 CDS YP_008736216.1 556567791 17445564 complement(5289555..5290235) 1 NC_022657.1 hypothetical protein 5290235 17445564 AFR_24485 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736216.1 5289555 R 1246995 CDS YP_008736217.1 556567792 17445565 complement(5290280..5291725) 1 NC_022657.1 COG0477 Permeases of the major facilitator superfamily; major facilitator superfamily transporter 5291725 17445565 AFR_24490 Actinoplanes friuliensis DSM 7358 major facilitator superfamily transporter YP_008736217.1 5290280 R 1246995 CDS YP_008736218.1 556567793 17445566 complement(5291771..5292589) 1 NC_022657.1 COG0789 Predicted transcriptional regulators; putative MerR family transcriptional regulator 5292589 17445566 AFR_24495 Actinoplanes friuliensis DSM 7358 putative MerR family transcriptional regulator YP_008736218.1 5291771 R 1246995 CDS YP_008736219.1 556567794 17445567 complement(5292582..5293085) 1 NC_022657.1 MerR family transcriptional regulator 5293085 17445567 AFR_24500 Actinoplanes friuliensis DSM 7358 MerR family transcriptional regulator YP_008736219.1 5292582 R 1246995 CDS YP_008736220.1 556567795 17445568 complement(5293153..5295060) 1 NC_022657.1 COG5520 O-Glycosyl hydrolase; glucosylceramidase 5295060 17445568 AFR_24505 Actinoplanes friuliensis DSM 7358 glucosylceramidase YP_008736220.1 5293153 R 1246995 CDS YP_008736221.1 556567796 17445569 5295241..5296209 1 NC_022657.1 COG1609 Transcriptional regulators; LacI family transcriptional regulator 5296209 17445569 AFR_24510 Actinoplanes friuliensis DSM 7358 LacI family transcriptional regulator YP_008736221.1 5295241 D 1246995 CDS YP_008736222.1 556567797 17445570 5296219..5297265 1 NC_022657.1 COG0673 Predicted dehydrogenases and related proteins; oxidoreductase domain-containing protein 5297265 17445570 AFR_24515 Actinoplanes friuliensis DSM 7358 oxidoreductase domain-containing protein YP_008736222.1 5296219 D 1246995 CDS YP_008736223.1 556567798 17445571 5297356..5300373 1 NC_022657.1 COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain; putative diguanylate cyclase/phosphodiesterase with PAS sensor 5300373 17445571 AFR_24520 Actinoplanes friuliensis DSM 7358 putative diguanylate cyclase/phosphodiesterase with PAS sensor YP_008736223.1 5297356 D 1246995 CDS YP_008736224.1 556567799 17445572 complement(5300505..5302457) 1 NC_022657.1 COG0480 Translation elongation factors (GTPases); small GTP-binding protein 5302457 17445572 AFR_24525 Actinoplanes friuliensis DSM 7358 small GTP-binding protein YP_008736224.1 5300505 R 1246995 CDS YP_008736225.1 556567800 17445573 5302691..5303386 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); putative acetyltransferase 5303386 17445573 AFR_24530 Actinoplanes friuliensis DSM 7358 putative acetyltransferase YP_008736225.1 5302691 D 1246995 CDS YP_008736226.1 556567801 17445574 complement(5303370..5303729) 1 NC_022657.1 COG2252 Permeases; hypothetical protein 5303729 17445574 AFR_24535 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736226.1 5303370 R 1246995 CDS YP_008736227.1 556567802 17445575 complement(5303739..5304914) 1 NC_022657.1 COG1960 Acyl-CoA dehydrogenases; putative acyl-CoA dehydrogenase 5304914 17445575 AFR_24540 Actinoplanes friuliensis DSM 7358 putative acyl-CoA dehydrogenase YP_008736227.1 5303739 R 1246995 CDS YP_008736228.1 556567803 17445576 5305075..5306079 1 NC_022657.1 COG0701 Predicted permeases; hypothetical protein 5306079 17445576 AFR_24545 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736228.1 5305075 D 1246995 CDS YP_008736229.1 556567804 17445577 5306076..5306786 1 NC_022657.1 COG3689 Predicted membrane protein; hypothetical protein 5306786 17445577 AFR_24550 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736229.1 5306076 D 1246995 CDS YP_008736230.1 556567805 17445578 5306783..5307859 1 NC_022657.1 hypothetical protein 5307859 17445578 AFR_24555 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736230.1 5306783 D 1246995 CDS YP_008736231.1 556567806 17445579 5308120..5309088 1 NC_022657.1 hypothetical protein 5309088 17445579 AFR_24560 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736231.1 5308120 D 1246995 CDS YP_008736232.1 556567807 17445580 complement(5309136..5311199) 1 NC_022657.1 COG3211 Predicted phosphatase; hypothetical protein 5311199 17445580 AFR_24565 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736232.1 5309136 R 1246995 CDS YP_008736233.1 556567808 17445581 complement(5311280..5312209) 1 NC_022657.1 COG0665 Glycine/D-amino acid oxidases (deaminating); d-amino-acid oxidase 5312209 17445581 AFR_24570 Actinoplanes friuliensis DSM 7358 d-amino-acid oxidase YP_008736233.1 5311280 R 1246995 CDS YP_008736234.1 556567809 17445582 5312286..5312576 1 NC_022657.1 COG4298 Uncharacterized protein conserved in bacteria; hypothetical protein 5312576 17445582 AFR_24575 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736234.1 5312286 D 1246995 CDS YP_008736235.1 556567810 17445583 5312657..5314336 1 NC_022657.1 COG0513 Superfamily II DNA and RNA helicases; ATP-independent RNA helicase 5314336 17445583 AFR_24580 Actinoplanes friuliensis DSM 7358 ATP-independent RNA helicase YP_008736235.1 5312657 D 1246995 CDS YP_008736236.1 556567811 17445584 complement(5314324..5314734) 1 NC_022657.1 COG5579 Uncharacterized conserved protein; hypothetical protein 5314734 17445584 AFR_24585 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736236.1 5314324 R 1246995 CDS YP_008736237.1 556567812 17445585 complement(5314731..5315129) 1 NC_022657.1 COG4572 Putative cation transport regulator; hypothetical protein 5315129 17445585 AFR_24590 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736237.1 5314731 R 1246995 CDS YP_008736238.1 556567813 17445586 5315247..5316344 1 NC_022657.1 COG4585 Signal transduction histidine kinase; integral membrane sensor signal transduction histidine kinase 5316344 17445586 AFR_24595 Actinoplanes friuliensis DSM 7358 integral membrane sensor signal transduction histidine kinase YP_008736238.1 5315247 D 1246995 CDS YP_008736239.1 556567814 17445587 5316356..5317015 1 NC_022657.1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; response regulator receiver 5317015 17445587 AFR_24600 Actinoplanes friuliensis DSM 7358 response regulator receiver YP_008736239.1 5316356 D 1246995 CDS YP_008736240.1 556567815 17445588 5317076..5318572 1 NC_022657.1 hypothetical protein 5318572 17445588 AFR_24605 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736240.1 5317076 D 1246995 CDS YP_008736241.1 556567816 17445589 5318833..5319210 1 NC_022657.1 hypothetical protein 5319210 17445589 AFR_24610 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736241.1 5318833 D 1246995 CDS YP_008736242.1 556567817 17445590 complement(5319214..5319678) 1 NC_022657.1 transmembrane transport protein 5319678 17445590 AFR_24615 Actinoplanes friuliensis DSM 7358 transmembrane transport protein YP_008736242.1 5319214 R 1246995 CDS YP_008736243.1 556567818 17445591 complement(5319675..5320193) 1 NC_022657.1 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; ECF subfamily RNA polymerase sigma-24 subunit 5320193 17445591 AFR_24620 Actinoplanes friuliensis DSM 7358 ECF subfamily RNA polymerase sigma-24 subunit YP_008736243.1 5319675 R 1246995 CDS YP_008736244.1 556567819 17445592 complement(5320265..5321146) 1 NC_022657.1 COG1266 Predicted metal-dependent membrane protease; abortive infection protein 5321146 17445592 AFR_24625 Actinoplanes friuliensis DSM 7358 abortive infection protein YP_008736244.1 5320265 R 1246995 CDS YP_008736245.1 556567820 17445593 complement(5321159..5321809) 1 NC_022657.1 COG1309 Transcriptional regulator; TetR family transcriptional regulator 5321809 17445593 AFR_24630 Actinoplanes friuliensis DSM 7358 TetR family transcriptional regulator YP_008736245.1 5321159 R 1246995 CDS YP_008736246.1 556567821 17445594 5321912..5322361 1 NC_022657.1 hypothetical protein 5322361 17445594 AFR_24635 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736246.1 5321912 D 1246995 CDS YP_008736247.1 556567822 17445595 5322386..5322991 1 NC_022657.1 COG4430 Uncharacterized protein conserved in bacteria; hypothetical protein 5322991 17445595 AFR_24640 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736247.1 5322386 D 1246995 CDS YP_008736248.1 556567823 17445596 complement(5322996..5323964) 1 NC_022657.1 COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases); aldo/keto reductase 5323964 17445596 AFR_24645 Actinoplanes friuliensis DSM 7358 aldo/keto reductase YP_008736248.1 5322996 R 1246995 CDS YP_008736249.1 556567824 17445597 complement(5324450..5325166) 1 NC_022657.1 hypothetical protein 5325166 17445597 AFR_24650 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736249.1 5324450 R 1246995 CDS YP_008736250.1 556567825 17445599 5325886..5326500 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); short-chain dehydrogenase/reductase SDR 5326500 17445599 AFR_24655 Actinoplanes friuliensis DSM 7358 short-chain dehydrogenase/reductase SDR YP_008736250.1 5325886 D 1246995 CDS YP_008736251.1 556567826 17445600 complement(5326466..5327479) 1 NC_022657.1 hypothetical protein 5327479 17445600 AFR_24660 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736251.1 5326466 R 1246995 CDS YP_008736252.1 556567827 17445601 complement(5327483..5329591) 1 NC_022657.1 COG1523 Type II secretory pathway, pullulanase PulA and related glycosidases; glycogen operon protein GlgX 5329591 17445601 AFR_24665 Actinoplanes friuliensis DSM 7358 glycogen operon protein GlgX YP_008736252.1 5327483 R 1246995 CDS YP_008736253.1 556567828 17445602 5329716..5331128 1 NC_022657.1 COG0477 Permeases of the major facilitator superfamily; efflux membrane protein 5331128 17445602 AFR_24670 Actinoplanes friuliensis DSM 7358 efflux membrane protein YP_008736253.1 5329716 D 1246995 CDS YP_008736254.1 556567829 17445603 5331128..5331928 1 NC_022657.1 COG2226 Methylase involved in ubiquinone/menaquinone biosynthesis; type 11 methyltransferase 5331928 17445603 AFR_24675 Actinoplanes friuliensis DSM 7358 type 11 methyltransferase YP_008736254.1 5331128 D 1246995 CDS YP_008736255.1 556567830 17445604 5331925..5332443 1 NC_022657.1 COG0645 Predicted kinase; hypothetical protein 5332443 17445604 AFR_24680 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736255.1 5331925 D 1246995 CDS YP_008736256.1 556567831 17445605 complement(5332433..5333287) 1 NC_022657.1 hypothetical protein 5333287 17445605 AFR_24685 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736256.1 5332433 R 1246995 CDS YP_008736257.1 556567832 17445606 5333466..5333801 1 NC_022657.1 COG0640 Predicted transcriptional regulators; ArsR family transcriptional regulator 5333801 17445606 AFR_24690 Actinoplanes friuliensis DSM 7358 ArsR family transcriptional regulator YP_008736257.1 5333466 D 1246995 CDS YP_008736258.1 556567833 17445607 5333798..5334259 1 NC_022657.1 COG3832 Uncharacterized conserved protein; activator of HSP90 ATPase 1 family protein 5334259 17445607 AFR_24695 Actinoplanes friuliensis DSM 7358 activator of HSP90 ATPase 1 family protein YP_008736258.1 5333798 D 1246995 CDS YP_008736259.1 556567834 17445608 complement(5334293..5335558) 1 NC_022657.1 COG2312 Erythromycin esterase homolog; erythromycin esterase 5335558 17445608 AFR_24700 Actinoplanes friuliensis DSM 7358 erythromycin esterase YP_008736259.1 5334293 R 1246995 CDS YP_008736260.1 556567835 17445609 complement(5335601..5336326) 1 NC_022657.1 hypothetical protein 5336326 17445609 AFR_24705 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736260.1 5335601 R 1246995 CDS YP_008736261.1 556567836 17445610 complement(5336319..5336879) 1 NC_022657.1 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; putative RNA polymerase ECF-subfamily sigma factor 5336879 17445610 AFR_24710 Actinoplanes friuliensis DSM 7358 putative RNA polymerase ECF-subfamily sigma factor YP_008736261.1 5336319 R 1246995 CDS YP_008736262.1 556567837 17445611 5336954..5338168 1 NC_022657.1 hypothetical protein 5338168 17445611 AFR_24715 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736262.1 5336954 D 1246995 CDS YP_008736263.1 556567838 17445612 complement(5338156..5338662) 1 NC_022657.1 COG1102 Cytidylate kinase; phosphotransferase 5338662 17445612 AFR_24720 Actinoplanes friuliensis DSM 7358 phosphotransferase YP_008736263.1 5338156 R 1246995 CDS YP_008736264.1 556567839 17445613 complement(5338659..5339003) 1 NC_022657.1 hypothetical protein 5339003 17445613 AFR_24725 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736264.1 5338659 R 1246995 CDS YP_008736265.1 556567840 17445614 complement(5339044..5340114) 1 NC_022657.1 COG4188 Predicted dienelactone hydrolase; lipase 5340114 17445614 AFR_24730 Actinoplanes friuliensis DSM 7358 lipase YP_008736265.1 5339044 R 1246995 CDS YP_008736266.1 556567841 17445615 5340222..5340665 1 NC_022657.1 COG2346 Truncated hemoglobins; oxygen-binding heme protein 5340665 17445615 AFR_24735 Actinoplanes friuliensis DSM 7358 oxygen-binding heme protein YP_008736266.1 5340222 D 1246995 CDS YP_008736267.1 556567842 17445616 complement(5340654..5342345) 1 NC_022657.1 COG2730 Endoglucanase; putative glycosyl hydrolase 5342345 17445616 AFR_24740 Actinoplanes friuliensis DSM 7358 putative glycosyl hydrolase YP_008736267.1 5340654 R 1246995 CDS YP_008736268.1 556567843 17445617 complement(5342436..5342867) 1 NC_022657.1 COG5637 Predicted integral membrane protein; polyketide cyclase/dehydrase 5342867 17445617 AFR_24745 Actinoplanes friuliensis DSM 7358 polyketide cyclase/dehydrase YP_008736268.1 5342436 R 1246995 CDS YP_008736269.1 556567844 17445618 complement(5342877..5343278) 1 NC_022657.1 COG1051 ADP-ribose pyrophosphatase; RNA pyrophosphohydrolase 5343278 17445618 AFR_24750 Actinoplanes friuliensis DSM 7358 RNA pyrophosphohydrolase YP_008736269.1 5342877 R 1246995 CDS YP_008736270.1 556567845 17445619 complement(5343275..5343805) 1 NC_022657.1 hypothetical protein 5343805 17445619 AFR_24755 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736270.1 5343275 R 1246995 CDS YP_008736271.1 556567846 17445620 complement(5343837..5348339) 1 NC_022657.1 COG3250 Beta-galactosidase/beta-glucuronidase; glycoside hydrolase family protein 5348339 17445620 AFR_24760 Actinoplanes friuliensis DSM 7358 glycoside hydrolase family protein YP_008736271.1 5343837 R 1246995 CDS YP_008736272.1 556567847 17445621 complement(5348368..5349732) 1 NC_022657.1 o-phthalyl amidase 5349732 17445621 AFR_24765 Actinoplanes friuliensis DSM 7358 o-phthalyl amidase YP_008736272.1 5348368 R 1246995 CDS YP_008736273.1 556567848 17445622 5349866..5350762 1 NC_022657.1 COG4188 Predicted dienelactone hydrolase; putative lipase 5350762 17445622 AFR_24770 Actinoplanes friuliensis DSM 7358 putative lipase YP_008736273.1 5349866 D 1246995 CDS YP_008736274.1 556567849 17445623 5350835..5351581 1 NC_022657.1 COG2343 Uncharacterized protein conserved in bacteria; hypothetical protein 5351581 17445623 AFR_24775 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736274.1 5350835 D 1246995 CDS YP_008736275.1 556567850 17445624 5351581..5352312 1 NC_022657.1 COG3246 Uncharacterized conserved protein; hypothetical protein 5352312 17445624 AFR_24780 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736275.1 5351581 D 1246995 CDS YP_008736276.1 556567851 17445625 complement(5352571..5354427) 1 NC_022657.1 COG3707 Response regulator with putative antiterminator output domain; Phosphoserine phosphatase rsbP 5354427 17445625 AFR_24785 Actinoplanes friuliensis DSM 7358 Phosphoserine phosphatase rsbP YP_008736276.1 5352571 R 1246995 CDS YP_008736277.1 556567852 17445626 5354674..5355504 1 NC_022657.1 COG1305 Transglutaminase-like enzymes, putative cysteine proteases; transglutaminase domain-containing protein 5355504 17445626 AFR_24790 Actinoplanes friuliensis DSM 7358 transglutaminase domain-containing protein YP_008736277.1 5354674 D 1246995 CDS YP_008736278.1 556567853 17445627 5355591..5359181 1 NC_022657.1 COG2319 FOG: WD40 repeat; peptidase C14 caspase catalytic subunit p20 5359181 17445627 AFR_24795 Actinoplanes friuliensis DSM 7358 peptidase C14 caspase catalytic subunit p20 YP_008736278.1 5355591 D 1246995 CDS YP_008736279.1 556567854 17445628 complement(5359178..5359936) 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); short-chain dehydrogenase/reductase SDR 5359936 17445628 AFR_24800 Actinoplanes friuliensis DSM 7358 short-chain dehydrogenase/reductase SDR YP_008736279.1 5359178 R 1246995 CDS YP_008736280.1 556567855 17445629 5360039..5360983 1 NC_022657.1 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; RNA polymerase factor sigma-70 5360983 17445629 AFR_24805 Actinoplanes friuliensis DSM 7358 RNA polymerase factor sigma-70 YP_008736280.1 5360039 D 1246995 CDS YP_008736281.1 556567856 17445630 complement(5360984..5361298) 1 NC_022657.1 COG2337 Growth inhibitor; hypothetical protein 5361298 17445630 AFR_24810 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736281.1 5360984 R 1246995 CDS YP_008736282.1 556567857 17445631 complement(5361341..5362753) 1 NC_022657.1 COG2199 FOG: GGDEF domain; hypothetical protein 5362753 17445631 AFR_24815 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736282.1 5361341 R 1246995 CDS YP_008736283.1 556567858 17445632 5362895..5364325 1 NC_022657.1 COG0362 6-phosphogluconate dehydrogenase; putative 6-phosphogluconate dehydrogenase 5364325 17445632 AFR_24820 Actinoplanes friuliensis DSM 7358 putative 6-phosphogluconate dehydrogenase YP_008736283.1 5362895 D 1246995 CDS YP_008736284.1 556567859 17445633 complement(5364365..5366668) 1 NC_022657.1 COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain; diguanylate cyclase 5366668 17445633 AFR_24825 Actinoplanes friuliensis DSM 7358 diguanylate cyclase YP_008736284.1 5364365 R 1246995 CDS YP_008736285.1 556567860 17445634 5366868..5369219 1 NC_022657.1 COG4585 Signal transduction histidine kinase; putative two-component system sensor kinase 5369219 17445634 AFR_24830 Actinoplanes friuliensis DSM 7358 putative two-component system sensor kinase YP_008736285.1 5366868 D 1246995 CDS YP_008736286.1 556567861 17445635 5369216..5369866 1 NC_022657.1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; putative two-component system response regulator 5369866 17445635 AFR_24835 Actinoplanes friuliensis DSM 7358 putative two-component system response regulator YP_008736286.1 5369216 D 1246995 CDS YP_008736287.1 556567862 17445636 complement(5369856..5371499) 1 NC_022657.1 COG0033 Phosphoglucomutase; phosphoglucomutase 5371499 17445636 AFR_24840 Actinoplanes friuliensis DSM 7358 phosphoglucomutase YP_008736287.1 5369856 R 1246995 CDS YP_008736288.1 556567863 17445637 5371668..5373305 1 NC_022657.1 COG2372 Uncharacterized protein, homolog of Cu resistance protein CopC; hypothetical protein 5373305 17445637 AFR_24845 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736288.1 5371668 D 1246995 CDS YP_008736289.1 556567864 17445638 5373328..5373693 1 NC_022657.1 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); hypothetical protein 5373693 17445638 AFR_24850 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736289.1 5373328 D 1246995 CDS YP_008736290.1 556567865 17445639 5373703..5374509 1 NC_022657.1 COG3022 Uncharacterized protein conserved in bacteria; hypothetical protein 5374509 17445639 AFR_24855 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736290.1 5373703 D 1246995 CDS YP_008736291.1 556567866 17445640 complement(5374516..5375124) 1 NC_022657.1 COG0545 FKBP-type peptidyl-prolyl cis-trans isomerases 1; FKBP-type peptidylprolyl isomerase 5375124 17445640 AFR_24860 Actinoplanes friuliensis DSM 7358 FKBP-type peptidylprolyl isomerase YP_008736291.1 5374516 R 1246995 CDS YP_008736292.1 556567867 17445641 5375584..5376435 1 NC_022657.1 COG0055 F0F1-type ATP synthase, beta subunit; hypothetical protein 5376435 17445641 AFR_24865 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736292.1 5375584 D 1246995 CDS YP_008736293.1 556567868 17445642 5376457..5380281 1 NC_022657.1 COG2409 Predicted drug exporters of the RND superfamily; hypothetical protein 5380281 17445642 AFR_24870 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736293.1 5376457 D 1246995 CDS YP_008736294.1 556567869 17445643 5380414..5381898 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); putative short-chain dehydrogenase 5381898 17445643 AFR_24875 Actinoplanes friuliensis DSM 7358 putative short-chain dehydrogenase YP_008736294.1 5380414 D 1246995 CDS YP_008736295.1 556567870 17445644 complement(5381903..5382265) 1 NC_022657.1 COG1733 Predicted transcriptional regulators; putative HTH-type transcriptional regulator 5382265 17445644 AFR_24880 Actinoplanes friuliensis DSM 7358 putative HTH-type transcriptional regulator YP_008736295.1 5381903 R 1246995 CDS YP_008736296.1 556567871 17445645 5382341..5383141 1 NC_022657.1 COG0702 Predicted nucleoside-diphosphate-sugar epimerases; NAD-dependent epimerase/dehydratase 5383141 17445645 AFR_24885 Actinoplanes friuliensis DSM 7358 NAD-dependent epimerase/dehydratase YP_008736296.1 5382341 D 1246995 CDS YP_008736297.1 556567872 17445646 complement(5383128..5383760) 1 NC_022657.1 COG0500 SAM-dependent methyltransferases; methyltransferase 5383760 17445646 AFR_24890 Actinoplanes friuliensis DSM 7358 methyltransferase YP_008736297.1 5383128 R 1246995 CDS YP_008736298.1 556567873 17445647 complement(5383762..5384991) 1 NC_022657.1 COG2312 Erythromycin esterase homolog; Erythromycin esterase type II 5384991 17445647 AFR_24895 Actinoplanes friuliensis DSM 7358 Erythromycin esterase type II YP_008736298.1 5383762 R 1246995 CDS YP_008736299.1 556567874 17445648 5385401..5385832 1 NC_022657.1 hypothetical protein 5385832 17445648 AFR_24900 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736299.1 5385401 D 1246995 CDS YP_008736300.1 556567875 17445649 complement(5385835..5386569) 1 NC_022657.1 COG4279 Uncharacterized conserved protein; hypothetical protein 5386569 17445649 AFR_24905 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736300.1 5385835 R 1246995 CDS YP_008736301.1 556567876 17445650 complement(5386562..5389507) 1 NC_022657.1 COG0553 Superfamily II DNA/RNA helicases, SNF2 family; putative SNF2-family helicase 5389507 17445650 AFR_24910 Actinoplanes friuliensis DSM 7358 putative SNF2-family helicase YP_008736301.1 5386562 R 1246995 CDS YP_008736302.1 556567877 17445651 complement(5389504..5389947) 1 NC_022657.1 hypothetical protein 5389947 17445651 AFR_24915 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736302.1 5389504 R 1246995 CDS YP_008736303.1 556567878 17445652 5390046..5390582 1 NC_022657.1 hypothetical protein 5390582 17445652 AFR_24920 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736303.1 5390046 D 1246995 CDS YP_008736304.1 556567879 17445653 complement(5390596..5393352) 1 NC_022657.1 COG0457 FOG: TPR repeat; hypothetical protein 5393352 17445653 AFR_24925 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736304.1 5390596 R 1246995 CDS YP_008736305.1 556567880 17445654 5393439..5394275 1 NC_022657.1 hypothetical protein 5394275 17445654 AFR_24930 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736305.1 5393439 D 1246995 CDS YP_008736306.1 556567881 17445655 complement(5394285..5394689) 1 NC_022657.1 COG1846 Transcriptional regulators; MarR family transcriptional regulator 5394689 17445655 AFR_24935 Actinoplanes friuliensis DSM 7358 MarR family transcriptional regulator YP_008736306.1 5394285 R 1246995 CDS YP_008736307.1 556567882 17445656 5394902..5396473 1 NC_022657.1 COG0477 Permeases of the major facilitator superfamily; drug resistance efflux protein 5396473 17445656 AFR_24940 Actinoplanes friuliensis DSM 7358 drug resistance efflux protein YP_008736307.1 5394902 D 1246995 CDS YP_008736308.1 556567883 17445657 complement(5396539..5397774) 1 NC_022657.1 COG1181 D-alanine-D-alanine ligase and related ATP-grasp enzymes; hypothetical protein 5397774 17445657 AFR_24945 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736308.1 5396539 R 1246995 CDS YP_008736309.1 556567884 17445658 complement(5397788..5398813) 1 NC_022657.1 COG2382 Enterochelin esterase and related enzymes; putative esterase 5398813 17445658 AFR_24950 Actinoplanes friuliensis DSM 7358 putative esterase YP_008736309.1 5397788 R 1246995 CDS YP_008736310.1 556567885 17445659 complement(5398855..5399205) 1 NC_022657.1 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); hypothetical protein 5399205 17445659 AFR_24955 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736310.1 5398855 R 1246995 CDS YP_008736311.1 556567886 17445660 5399574..5401034 1 NC_022657.1 COG0531 Amino acid transporters; putative amino acid permease 5401034 17445660 AFR_24960 Actinoplanes friuliensis DSM 7358 putative amino acid permease YP_008736311.1 5399574 D 1246995 CDS YP_008736312.1 556567887 17445661 5401031..5401897 1 NC_022657.1 COG0589 Universal stress protein UspA and related nucleotide-binding proteins; hypothetical protein 5401897 17445661 AFR_24965 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736312.1 5401031 D 1246995 CDS YP_008736313.1 556567888 17445662 5401969..5402586 1 NC_022657.1 hypothetical protein 5402586 17445662 AFR_24970 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736313.1 5401969 D 1246995 CDS YP_008736314.1 556567889 17445663 complement(5402571..5403560) 1 NC_022657.1 COG0515 Serine/threonine protein kinase; putative serine/threonine protein kinase 5403560 17445663 AFR_24975 Actinoplanes friuliensis DSM 7358 putative serine/threonine protein kinase YP_008736314.1 5402571 R 1246995 CDS YP_008736315.1 556567890 17445664 complement(5403642..5404472) 1 NC_022657.1 hypothetical protein 5404472 17445664 AFR_24980 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736315.1 5403642 R 1246995 CDS YP_008736316.1 556567891 17445665 complement(5404475..5404825) 1 NC_022657.1 hypothetical protein 5404825 17445665 AFR_24985 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736316.1 5404475 R 1246995 CDS YP_008736317.1 556567892 17445666 complement(5405801..5406715) 1 NC_022657.1 hypothetical protein 5406715 17445666 AFR_24990 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736317.1 5405801 R 1246995 CDS YP_008736318.1 556567893 17445667 complement(5406795..5407730) 1 NC_022657.1 COG0457 FOG: TPR repeat; putative sulfotransferase 5407730 17445667 AFR_24995 Actinoplanes friuliensis DSM 7358 putative sulfotransferase YP_008736318.1 5406795 R 1246995 CDS YP_008736319.1 556567894 17445668 5408596..5409498 1 NC_022657.1 COG0463 Glycosyltransferases involved in cell wall biogenesis; putative glycosyltransferase 5409498 17445668 AFR_25000 Actinoplanes friuliensis DSM 7358 putative glycosyltransferase YP_008736319.1 5408596 D 1246995 CDS YP_008736320.1 556567895 17445669 5409549..5410496 1 NC_022657.1 COG0463 Glycosyltransferases involved in cell wall biogenesis; family 2 glycosyl transferase 5410496 17445669 AFR_25005 Actinoplanes friuliensis DSM 7358 family 2 glycosyl transferase YP_008736320.1 5409549 D 1246995 CDS YP_008736321.1 556567896 17445670 5410493..5411866 1 NC_022657.1 COG0463 Glycosyltransferases involved in cell wall biogenesis; glycosyl transferase family 2 protein 5411866 17445670 AFR_25010 Actinoplanes friuliensis DSM 7358 glycosyl transferase family 2 protein YP_008736321.1 5410493 D 1246995 CDS YP_008736322.1 556567897 17445671 5412022..5415237 1 NC_022657.1 putative transmembrane protein 5415237 17445671 AFR_25015 Actinoplanes friuliensis DSM 7358 putative transmembrane protein YP_008736322.1 5412022 D 1246995 CDS YP_008736323.1 556567898 17445672 5415234..5416190 1 NC_022657.1 hypothetical protein 5416190 17445672 AFR_25020 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736323.1 5415234 D 1246995 CDS YP_008736324.1 556567899 17445673 5416286..5417155 1 NC_022657.1 COG0190 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase; methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase 5417155 17445673 AFR_25025 Actinoplanes friuliensis DSM 7358 methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase YP_008736324.1 5416286 D 1246995 CDS YP_008736325.1 556567900 17445674 complement(5417145..5418197) 1 NC_022657.1 COG4124 Beta-mannanase; glycoside hydrolase family protein 5418197 17445674 AFR_25030 Actinoplanes friuliensis DSM 7358 glycoside hydrolase family protein YP_008736325.1 5417145 R 1246995 CDS YP_008736326.1 556567901 17445675 complement(5418194..5418988) 1 NC_022657.1 COG0726 Predicted xylanase/chitin deacetylase; hypothetical protein 5418988 17445675 AFR_25035 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736326.1 5418194 R 1246995 CDS YP_008736327.1 556567902 17445676 5419145..5419393 1 NC_022657.1 hypothetical protein 5419393 17445676 AFR_25040 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736327.1 5419145 D 1246995 CDS YP_008736328.1 556567903 17445677 5419460..5420110 1 NC_022657.1 hypothetical protein 5420110 17445677 AFR_25045 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736328.1 5419460 D 1246995 CDS YP_008736329.1 556567904 17445678 5420144..5421325 1 NC_022657.1 COG1408 Predicted phosphohydrolases; hypothetical protein 5421325 17445678 AFR_25050 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736329.1 5420144 D 1246995 CDS YP_008736330.1 556567905 17445679 complement(5421306..5422202) 1 NC_022657.1 COG3570 Streptomycin 6-kinase; aminoglycoside/hydroxyurea antibiotic resistance kinase 5422202 17445679 AFR_25055 Actinoplanes friuliensis DSM 7358 aminoglycoside/hydroxyurea antibiotic resistance kinase YP_008736330.1 5421306 R 1246995 CDS YP_008736331.1 556567906 17445680 5422313..5425774 1 NC_022657.1 COG1132 ABC-type multidrug transport system, ATPase and permease components; Multidrug resistance protein 1 5425774 17445680 AFR_25060 Actinoplanes friuliensis DSM 7358 Multidrug resistance protein 1 YP_008736331.1 5422313 D 1246995 CDS YP_008736332.1 556567907 17445681 complement(5427814..5428668) 1 NC_022657.1 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain; putative trypsin-like serine protease 5428668 17445681 AFR_25065 Actinoplanes friuliensis DSM 7358 putative trypsin-like serine protease YP_008736332.1 5427814 R 1246995 CDS YP_008736333.1 556567908 17445682 complement(5428694..5429395) 1 NC_022657.1 COG0491 Zn-dependent hydrolases, including glyoxylases; putative metallo-beta-lactamase-like protein 5429395 17445682 AFR_25070 Actinoplanes friuliensis DSM 7358 putative metallo-beta-lactamase-like protein YP_008736333.1 5428694 R 1246995 CDS YP_008736334.1 556567909 17445683 5429500..5430471 1 NC_022657.1 COG1266 Predicted metal-dependent membrane protease; hypothetical protein 5430471 17445683 AFR_25075 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736334.1 5429500 D 1246995 CDS YP_008736335.1 556567910 17445684 5430600..5431067 1 NC_022657.1 hypothetical protein 5431067 17445684 AFR_25080 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736335.1 5430600 D 1246995 CDS YP_008736336.1 556567911 17445685 5431225..5431503 1 NC_022657.1 COG3409 Putative peptidoglycan-binding domain-containing protein; hypothetical protein 5431503 17445685 AFR_25085 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736336.1 5431225 D 1246995 CDS YP_008736337.1 556567912 17445686 5431609..5432619 1 NC_022657.1 COG1609 Transcriptional regulators; LacI family transcriptional regulator 5432619 17445686 AFR_25090 Actinoplanes friuliensis DSM 7358 LacI family transcriptional regulator YP_008736337.1 5431609 D 1246995 CDS YP_008736338.1 556567913 17445687 complement(5432621..5434429) 1 NC_022657.1 COG2837 Predicted iron-dependent peroxidase; dyp-type peroxidase 5434429 17445687 AFR_25095 Actinoplanes friuliensis DSM 7358 dyp-type peroxidase YP_008736338.1 5432621 R 1246995 CDS YP_008736339.1 556567914 17445688 complement(5434426..5435022) 1 NC_022657.1 COG0085 DNA-directed RNA polymerase, beta subunit/140 kD subunit; hypothetical protein 5435022 17445688 AFR_25100 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736339.1 5434426 R 1246995 CDS YP_008736340.1 556567915 17445689 5435071..5437788 1 NC_022657.1 COG3899 Predicted ATPase; LuxR family transcriptional regulator 5437788 17445689 AFR_25105 Actinoplanes friuliensis DSM 7358 LuxR family transcriptional regulator YP_008736340.1 5435071 D 1246995 CDS YP_008736341.1 556567916 17445690 complement(5437797..5438369) 1 NC_022657.1 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; ECF subfamily RNA polymerase sigma-24 subunit 5438369 17445690 AFR_25110 Actinoplanes friuliensis DSM 7358 ECF subfamily RNA polymerase sigma-24 subunit YP_008736341.1 5437797 R 1246995 CDS YP_008736342.1 556567917 17445691 complement(5438499..5439515) 1 NC_022657.1 COG1619 Uncharacterized proteins, homologs of microcin C7 resistance protein MccF; peptidase U61 LD-carboxypeptidase A 5439515 17445691 AFR_25115 Actinoplanes friuliensis DSM 7358 peptidase U61 LD-carboxypeptidase A YP_008736342.1 5438499 R 1246995 CDS YP_008736343.1 556567918 17445692 complement(5439575..5440666) 1 NC_022657.1 COG2508 Regulator of polyketide synthase expression; hypothetical protein 5440666 17445692 AFR_25120 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736343.1 5439575 R 1246995 CDS YP_008736344.1 556567919 17445693 5440831..5441889 1 NC_022657.1 COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1; oxidoreductase FAD-binding domain protein 5441889 17445693 AFR_25125 Actinoplanes friuliensis DSM 7358 oxidoreductase FAD-binding domain protein YP_008736344.1 5440831 D 1246995 CDS YP_008736345.1 556567920 17445694 5441925..5443130 1 NC_022657.1 COG3239 Fatty acid desaturase; fatty acid desaturase 5443130 17445694 AFR_25130 Actinoplanes friuliensis DSM 7358 fatty acid desaturase YP_008736345.1 5441925 D 1246995 CDS YP_008736346.1 556567921 17445695 5443155..5444396 1 NC_022657.1 COG0277 FAD/FMN-containing dehydrogenases; putative FAD-dependent oxidoreductase 5444396 17445695 AFR_25135 Actinoplanes friuliensis DSM 7358 putative FAD-dependent oxidoreductase YP_008736346.1 5443155 D 1246995 CDS YP_008736347.1 556567922 17445696 complement(5444393..5445289) 1 NC_022657.1 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; RNA polymerase factor sigma-70 5445289 17445696 AFR_25140 Actinoplanes friuliensis DSM 7358 RNA polymerase factor sigma-70 YP_008736347.1 5444393 R 1246995 CDS YP_008736348.1 556567923 17445697 5445447..5448479 1 NC_022657.1 cell wall-binding protein 5448479 17445697 AFR_25145 Actinoplanes friuliensis DSM 7358 cell wall-binding protein YP_008736348.1 5445447 D 1246995 CDS YP_008736349.1 556567924 17445698 5448612..5449646 1 NC_022657.1 COG2072 Predicted flavoprotein involved in K+ transport; FAD-dependent pyridine nucleotide-disulfide oxidoreductase 5449646 17445698 AFR_25150 Actinoplanes friuliensis DSM 7358 FAD-dependent pyridine nucleotide-disulfide oxidoreductase YP_008736349.1 5448612 D 1246995 CDS YP_008736350.1 556567925 17445699 5449723..5450541 1 NC_022657.1 COG3652 Predicted outer membrane protein; hypothetical protein 5450541 17445699 AFR_25155 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736350.1 5449723 D 1246995 CDS YP_008736351.1 556567926 17445700 5450683..5452551 1 NC_022657.1 COG3158 K+ transporter; potassium transporter 5452551 17445700 AFR_25160 Actinoplanes friuliensis DSM 7358 potassium transporter YP_008736351.1 5450683 D 1246995 CDS YP_008736352.1 556567927 17445701 5452565..5453161 1 NC_022657.1 COG0262 Dihydrofolate reductase; riboflavin biosynthesis protein RibD 5453161 17445701 AFR_25165 Actinoplanes friuliensis DSM 7358 riboflavin biosynthesis protein RibD YP_008736352.1 5452565 D 1246995 CDS YP_008736353.1 556567928 17445702 5453299..5454429 1 NC_022657.1 COG1690 Uncharacterized conserved protein; hypothetical protein 5454429 17445702 AFR_25170 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736353.1 5453299 D 1246995 CDS YP_008736354.1 556567929 17445703 complement(5454434..5456365) 1 NC_022657.1 COG0793 Periplasmic protease; hypothetical protein 5456365 17445703 AFR_25175 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736354.1 5454434 R 1246995 CDS YP_008736355.1 556567930 17445704 5456505..5459102 1 NC_022657.1 COG0542 ATPases with chaperone activity, ATP-binding subunit; hypothetical protein 5459102 17445704 AFR_25180 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736355.1 5456505 D 1246995 CDS YP_008736356.1 556567931 17445705 5459129..5460880 1 NC_022657.1 COG1960 Acyl-CoA dehydrogenases; acyl-CoA dehydrogenase domain-containing protein 5460880 17445705 AFR_25185 Actinoplanes friuliensis DSM 7358 acyl-CoA dehydrogenase domain-containing protein YP_008736356.1 5459129 D 1246995 CDS YP_008736357.1 556567932 17445706 5460871..5461647 1 NC_022657.1 COG0584 Glycerophosphoryl diester phosphodiesterase; glycerophosphoryl diester phosphodiesterase 5461647 17445706 AFR_25190 Actinoplanes friuliensis DSM 7358 glycerophosphoryl diester phosphodiesterase YP_008736357.1 5460871 D 1246995 CDS YP_008736358.1 556567933 17445707 complement(5461771..5462517) 1 NC_022657.1 COG2159 Predicted metal-dependent hydrolase of the TIM-barrel fold; amidohydrolase 5462517 17445707 AFR_25195 Actinoplanes friuliensis DSM 7358 amidohydrolase YP_008736358.1 5461771 R 1246995 CDS YP_008736359.1 556567934 17445708 5463538..5466045 1 NC_022657.1 COG3534 Alpha-L-arabinofuranosidase; putative alpha-L-arabinofuranosidase 5466045 17445708 AFR_25200 Actinoplanes friuliensis DSM 7358 putative alpha-L-arabinofuranosidase YP_008736359.1 5463538 D 1246995 CDS YP_008736360.1 556567935 17445709 5466054..5467055 1 NC_022657.1 COG3940 Predicted beta-xylosidase; putative glycosyl hydrolase 5467055 17445709 AFR_25205 Actinoplanes friuliensis DSM 7358 putative glycosyl hydrolase YP_008736360.1 5466054 D 1246995 CDS YP_008736361.1 556567936 17445710 5467150..5468550 1 NC_022657.1 COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes; dihydrolipoamide dehydrogenase 5468550 17445710 AFR_25210 Actinoplanes friuliensis DSM 7358 dihydrolipoamide dehydrogenase YP_008736361.1 5467150 D 1246995 CDS YP_008736362.1 556567937 17445711 complement(5468600..5468899) 1 NC_022657.1 hypothetical protein 5468899 17445711 AFR_25215 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736362.1 5468600 R 1246995 CDS YP_008736363.1 556567938 17445712 complement(5469562..5469846) 1 NC_022657.1 hypothetical protein 5469846 17445712 AFR_25220 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736363.1 5469562 R 1246995 CDS YP_008736364.1 556567939 17445713 5470283..5471065 1 NC_022657.1 hypothetical protein 5471065 17445713 AFR_25225 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736364.1 5470283 D 1246995 CDS YP_008736365.1 556567940 17445714 5471251..5471736 1 NC_022657.1 hypothetical protein 5471736 17445714 AFR_25230 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736365.1 5471251 D 1246995 CDS YP_008736366.1 556567941 17445715 complement(5471729..5472667) 1 NC_022657.1 hypothetical protein 5472667 17445715 AFR_25235 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736366.1 5471729 R 1246995 CDS YP_008736367.1 556567942 17445716 5472709..5473215 1 NC_022657.1 hypothetical protein 5473215 17445716 AFR_25240 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736367.1 5472709 D 1246995 CDS YP_008736368.1 556567943 17445717 5473233..5474027 1 NC_022657.1 hypothetical protein 5474027 17445717 AFR_25245 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736368.1 5473233 D 1246995 CDS YP_008736369.1 556567944 17445718 complement(5474037..5475167) 1 NC_022657.1 COG0673 Predicted dehydrogenases and related proteins; oxidoreductase domain-containing protein 5475167 17445718 AFR_25250 Actinoplanes friuliensis DSM 7358 oxidoreductase domain-containing protein YP_008736369.1 5474037 R 1246995 CDS YP_008736370.1 556567945 17445719 complement(5475164..5476648) 1 NC_022657.1 COG0246 Mannitol-1-phosphate/altronate dehydrogenases; mannitol dehydrogenase domain protein 5476648 17445719 AFR_25255 Actinoplanes friuliensis DSM 7358 mannitol dehydrogenase domain protein YP_008736370.1 5475164 R 1246995 CDS YP_008736371.1 556567946 17445720 complement(5476645..5477946) 1 NC_022657.1 COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily; mandelate racemase/muconate lactonizing protein 5477946 17445720 AFR_25260 Actinoplanes friuliensis DSM 7358 mandelate racemase/muconate lactonizing protein YP_008736371.1 5476645 R 1246995 CDS YP_008736372.1 556567947 17445721 complement(5477943..5479346) 1 NC_022657.1 COG1904 Glucuronate isomerase; glucuronate isomerase 5479346 17445721 AFR_25265 Actinoplanes friuliensis DSM 7358 glucuronate isomerase YP_008736372.1 5477943 R 1246995 CDS YP_008736373.1 556567948 17445722 complement(5479370..5480689) 1 NC_022657.1 COG0673 Predicted dehydrogenases and related proteins; oxidoreductase domain-containing protein 5480689 17445722 AFR_25270 Actinoplanes friuliensis DSM 7358 oxidoreductase domain-containing protein YP_008736373.1 5479370 R 1246995 CDS YP_008736374.1 556567949 17445723 5480971..5481984 1 NC_022657.1 COG1609 Transcriptional regulators; LacI family transcriptional regulator 5481984 17445723 AFR_25275 Actinoplanes friuliensis DSM 7358 LacI family transcriptional regulator YP_008736374.1 5480971 D 1246995 CDS YP_008736375.1 556567950 17445724 5481991..5483322 1 NC_022657.1 COG1653 ABC-type sugar transport system, periplasmic component; family 1 extracellular solute-binding protein 5483322 17445724 AFR_25280 Actinoplanes friuliensis DSM 7358 family 1 extracellular solute-binding protein YP_008736375.1 5481991 D 1246995 CDS YP_008736376.1 556567951 17445725 5483331..5484308 1 NC_022657.1 COG1175 ABC-type sugar transport systems, permease components; binding-protein-dependent transport system inner membrane protein 5484308 17445725 AFR_25285 Actinoplanes friuliensis DSM 7358 binding-protein-dependent transport system inner membrane protein YP_008736376.1 5483331 D 1246995 CDS YP_008736377.1 556567952 17445726 5484308..5485138 1 NC_022657.1 COG0395 ABC-type sugar transport system, permease component; binding-protein-dependent transport systems inner membrane component 5485138 17445726 AFR_25290 Actinoplanes friuliensis DSM 7358 binding-protein-dependent transport systems inner membrane component YP_008736377.1 5484308 D 1246995 CDS YP_008736378.1 556567953 17445727 5485135..5485716 1 NC_022657.1 hypothetical protein 5485716 17445727 AFR_25295 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736378.1 5485135 D 1246995 CDS YP_008736379.1 556567954 17445728 5485775..5486269 1 NC_022657.1 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; RNA polymerase sigma factor sigM 5486269 17445728 AFR_25300 Actinoplanes friuliensis DSM 7358 RNA polymerase sigma factor sigM YP_008736379.1 5485775 D 1246995 CDS YP_008736380.1 556567955 17445729 5486281..5487072 1 NC_022657.1 hypothetical protein 5487072 17445729 AFR_25305 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736380.1 5486281 D 1246995 CDS YP_008736381.1 556567956 17445730 complement(5487088..5487522) 1 NC_022657.1 COG0517 FOG: CBS domain; hypothetical protein 5487522 17445730 AFR_25310 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736381.1 5487088 R 1246995 CDS YP_008736382.1 556567957 17445731 complement(5487548..5488498) 1 NC_022657.1 hypothetical protein 5488498 17445731 AFR_25315 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736382.1 5487548 R 1246995 CDS YP_008736383.1 556567958 17445732 5488538..5489119 1 NC_022657.1 COG1309 Transcriptional regulator; TetR family transcriptional regulator 5489119 17445732 AFR_25320 Actinoplanes friuliensis DSM 7358 TetR family transcriptional regulator YP_008736383.1 5488538 D 1246995 CDS YP_008736384.1 556567959 17445733 5489148..5490077 1 NC_022657.1 COG3021 Uncharacterized protein conserved in bacteria; hypothetical protein 5490077 17445733 AFR_25325 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736384.1 5489148 D 1246995 CDS YP_008736385.1 556567960 17445734 5490157..5490411 1 NC_022657.1 COG1983 Putative stress-responsive transcriptional regulator; hypothetical protein 5490411 17445734 AFR_25330 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736385.1 5490157 D 1246995 CDS YP_008736386.1 556567961 17445735 complement(5490408..5492114) 1 NC_022657.1 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases; FAD-binding monooxygenase 5492114 17445735 AFR_25335 Actinoplanes friuliensis DSM 7358 FAD-binding monooxygenase YP_008736386.1 5490408 R 1246995 CDS YP_008736387.1 556567962 17445736 complement(5492120..5493976) 1 NC_022657.1 COG1454 Alcohol dehydrogenase, class IV; maleylacetate reductase 5493976 17445736 AFR_25340 Actinoplanes friuliensis DSM 7358 maleylacetate reductase YP_008736387.1 5492120 R 1246995 CDS YP_008736388.1 556567963 17445737 complement(5494027..5494896) 1 NC_022657.1 COG2207 AraC-type DNA-binding domain-containing proteins; AraC-family regulator 5494896 17445737 AFR_25345 Actinoplanes friuliensis DSM 7358 AraC-family regulator YP_008736388.1 5494027 R 1246995 CDS YP_008736389.1 556567964 17445738 5494968..5496482 1 NC_022657.1 COG0515 Serine/threonine protein kinase; Calcium/calmodulin-dependent protein kinase type II beta chain 5496482 17445738 AFR_25350 Actinoplanes friuliensis DSM 7358 Calcium/calmodulin-dependent protein kinase type II beta chain YP_008736389.1 5494968 D 1246995 CDS YP_008736390.1 556567965 17445739 complement(5497043..5497822) 1 NC_022657.1 COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases); aldo/keto reductase 5497822 17445739 AFR_25355 Actinoplanes friuliensis DSM 7358 aldo/keto reductase YP_008736390.1 5497043 R 1246995 CDS YP_008736391.1 556567966 17445740 complement(5497900..5499156) 1 NC_022657.1 COG0675 Transposase and inactivated derivatives; transposase, IS605 OrfB family protein 5499156 17445740 AFR_25360 Actinoplanes friuliensis DSM 7358 transposase, IS605 OrfB family protein YP_008736391.1 5497900 R 1246995 CDS YP_008736392.1 556567967 17445741 complement(5499699..5500664) 1 NC_022657.1 COG1472 Beta-glucosidase-related glycosidases; Beta-N-acetylhexosaminidase 5500664 17445741 AFR_25375 Actinoplanes friuliensis DSM 7358 Beta-N-acetylhexosaminidase YP_008736392.1 5499699 R 1246995 CDS YP_008736393.1 556567968 17445742 5501038..5502117 1 NC_022657.1 COG2755 Lysophospholipase L1 and related esterases; Polypeptide N-acetylgalactosaminyltransferase 13 5502117 17445742 AFR_25380 Actinoplanes friuliensis DSM 7358 Polypeptide N-acetylgalactosaminyltransferase 13 YP_008736393.1 5501038 D 1246995 CDS YP_008736394.1 556567969 17445743 complement(5502121..5503065) 1 NC_022657.1 COG3397 Uncharacterized protein conserved in bacteria; putative chitin-binding protein 5503065 17445743 AFR_25385 Actinoplanes friuliensis DSM 7358 putative chitin-binding protein YP_008736394.1 5502121 R 1246995 CDS YP_008736395.1 556567970 17445744 5503227..5503595 1 NC_022657.1 COG0545 FKBP-type peptidyl-prolyl cis-trans isomerases 1; FKBP-type peptidylprolyl isomerase 5503595 17445744 AFR_25390 Actinoplanes friuliensis DSM 7358 FKBP-type peptidylprolyl isomerase YP_008736395.1 5503227 D 1246995 CDS YP_008736396.1 556567971 17445745 complement(5503716..5504573) 1 NC_022657.1 hypothetical protein 5504573 17445745 AFR_25395 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736396.1 5503716 R 1246995 CDS YP_008736397.1 556567972 17445746 complement(5504739..5505605) 1 NC_022657.1 COG0395 ABC-type sugar transport system, permease component; binding-protein-dependent transport systems inner membrane component 5505605 17445746 AFR_25400 Actinoplanes friuliensis DSM 7358 binding-protein-dependent transport systems inner membrane component YP_008736397.1 5504739 R 1246995 CDS YP_008736398.1 556567973 17445747 complement(5505602..5506459) 1 NC_022657.1 COG1175 ABC-type sugar transport systems, permease components; binding-protein-dependent transport systems inner membrane component 5506459 17445747 AFR_25405 Actinoplanes friuliensis DSM 7358 binding-protein-dependent transport systems inner membrane component YP_008736398.1 5505602 R 1246995 CDS YP_008736399.1 556567974 17445748 complement(5506579..5507925) 1 NC_022657.1 COG1653 ABC-type sugar transport system, periplasmic component; extracellular solute-binding protein family 1 protein 5507925 17445748 AFR_25410 Actinoplanes friuliensis DSM 7358 extracellular solute-binding protein family 1 protein YP_008736399.1 5506579 R 1246995 CDS YP_008736400.1 556567975 17445749 complement(5508097..5508294) 1 NC_022657.1 COG2501 Uncharacterized conserved protein; hypothetical protein 5508294 17445749 AFR_25415 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736400.1 5508097 R 1246995 CDS YP_008736401.1 556567976 17445750 5508275..5509201 1 NC_022657.1 hypothetical protein 5509201 17445750 AFR_25420 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736401.1 5508275 D 1246995 CDS YP_008736402.1 556567977 17445751 complement(5509352..5510290) 1 NC_022657.1 COG0618 Exopolyphosphatase-related proteins; exopolyphosphatase-like protein 5510290 17445751 AFR_25425 Actinoplanes friuliensis DSM 7358 exopolyphosphatase-like protein YP_008736402.1 5509352 R 1246995 CDS YP_008736403.1 556567978 17445752 5510448..5511941 1 NC_022657.1 COG0364 Glucose-6-phosphate 1-dehydrogenase; putative glucose-6-phosphate dehydrogenase 5511941 17445752 AFR_25430 Actinoplanes friuliensis DSM 7358 putative glucose-6-phosphate dehydrogenase YP_008736403.1 5510448 D 1246995 CDS YP_008736404.1 556567979 17445753 complement(5511943..5512413) 1 NC_022657.1 COG1225 Peroxiredoxin; alkyl hydroperoxide reductase 5512413 17445753 AFR_25435 Actinoplanes friuliensis DSM 7358 alkyl hydroperoxide reductase YP_008736404.1 5511943 R 1246995 CDS YP_008736405.1 556567980 17445754 5512542..5512874 1 NC_022657.1 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); Anti-sigma F factor antagonist 5512874 17445754 AFR_25440 Actinoplanes friuliensis DSM 7358 Anti-sigma F factor antagonist YP_008736405.1 5512542 D 1246995 CDS YP_008736406.1 556567981 17445755 complement(5512915..5514912) 1 NC_022657.1 hypothetical protein 5514912 17445755 AFR_25445 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736406.1 5512915 R 1246995 CDS YP_008736407.1 556567982 17445756 complement(5514909..5516063) 1 NC_022657.1 COG0775 Nucleoside phosphorylase; purine phosphorylase family 1 5516063 17445756 AFR_25450 Actinoplanes friuliensis DSM 7358 purine phosphorylase family 1 YP_008736407.1 5514909 R 1246995 CDS YP_008736408.1 556567983 17445757 complement(5516063..5516572) 1 NC_022657.1 COG1051 ADP-ribose pyrophosphatase; NUDIX hydrolase 5516572 17445757 AFR_25455 Actinoplanes friuliensis DSM 7358 NUDIX hydrolase YP_008736408.1 5516063 R 1246995 CDS YP_008736409.1 556567984 17445758 5517053..5518141 1 NC_022657.1 COG4213 ABC-type xylose transport system, periplasmic component; solute-binding protein 5518141 17445758 AFR_25460 Actinoplanes friuliensis DSM 7358 solute-binding protein YP_008736409.1 5517053 D 1246995 CDS YP_008736410.1 556567985 17445759 5518138..5518920 1 NC_022657.1 COG1129 ABC-type sugar transport system, ATPase component; ABC transporter 5518920 17445759 AFR_25465 Actinoplanes friuliensis DSM 7358 ABC transporter YP_008736410.1 5518138 D 1246995 CDS YP_008736411.1 556567986 17445760 5518917..5520197 1 NC_022657.1 COG4214 ABC-type xylose transport system, permease component; inner-membrane translocator 5520197 17445760 AFR_25470 Actinoplanes friuliensis DSM 7358 inner-membrane translocator YP_008736411.1 5518917 D 1246995 CDS YP_008736412.1 556567987 17445761 complement(5520244..5521635) 1 NC_022657.1 peptidoglycan-binding protein 5521635 17445761 AFR_25475 Actinoplanes friuliensis DSM 7358 peptidoglycan-binding protein YP_008736412.1 5520244 R 1246995 CDS YP_008736413.1 556567988 17445762 5521781..5522167 1 NC_022657.1 hypothetical protein 5522167 17445762 AFR_25480 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736413.1 5521781 D 1246995 CDS YP_008736414.1 556567989 17445763 complement(5522151..5523467) 1 NC_022657.1 COG0642 Signal transduction histidine kinase; integral membrane sensor signal transduction histidine kinase 5523467 17445763 AFR_25485 Actinoplanes friuliensis DSM 7358 integral membrane sensor signal transduction histidine kinase YP_008736414.1 5522151 R 1246995 CDS YP_008736415.1 556567990 17445764 5523512..5523880 1 NC_022657.1 hypothetical protein 5523880 17445764 AFR_25490 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736415.1 5523512 D 1246995 CDS YP_008736416.1 556567991 17445765 5523877..5524551 1 NC_022657.1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; response regulator mprA 5524551 17445765 AFR_25495 Actinoplanes friuliensis DSM 7358 response regulator mprA YP_008736416.1 5523877 D 1246995 CDS YP_008736417.1 556567992 17445766 complement(5524571..5525617) 1 NC_022657.1 COG1940 Transcriptional regulator/sugar kinase; ROK family protein 5525617 17445766 AFR_25500 Actinoplanes friuliensis DSM 7358 ROK family protein YP_008736417.1 5524571 R 1246995 CDS YP_008736418.1 556567993 17445767 5525733..5527277 1 NC_022657.1 COG5267 Uncharacterized protein conserved in bacteria; hypothetical protein 5527277 17445767 AFR_25505 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736418.1 5525733 D 1246995 CDS YP_008736419.1 556567994 17445768 5527283..5528554 1 NC_022657.1 COG4102 Uncharacterized protein conserved in bacteria; hypothetical protein 5528554 17445768 AFR_25510 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736419.1 5527283 D 1246995 CDS YP_008736420.1 556567995 17445769 complement(5528560..5529090) 1 NC_022657.1 hypothetical protein 5529090 17445769 AFR_25515 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736420.1 5528560 R 1246995 CDS YP_008736421.1 556567996 17445770 complement(5529112..5529351) 1 NC_022657.1 hypothetical protein 5529351 17445770 AFR_25520 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736421.1 5529112 R 1246995 CDS YP_008736422.1 556567997 17445771 complement(5529527..5530780) 1 NC_022657.1 COG4214 ABC-type xylose transport system, permease component; putative multiple sugar transport system permease 5530780 17445771 AFR_25525 Actinoplanes friuliensis DSM 7358 putative multiple sugar transport system permease YP_008736422.1 5529527 R 1246995 CDS YP_008736423.1 556567998 17445772 complement(5530786..5532315) 1 NC_022657.1 COG1129 ABC-type sugar transport system, ATPase component; L-arabinose transport ATP-binding protein araG 5532315 17445772 AFR_25530 Actinoplanes friuliensis DSM 7358 L-arabinose transport ATP-binding protein araG YP_008736423.1 5530786 R 1246995 CDS YP_008736424.1 556567999 17445773 complement(5532391..5533521) 1 NC_022657.1 COG4213 ABC-type xylose transport system, periplasmic component; putative ABC transporter substrate-binding protein 5533521 17445773 AFR_25535 Actinoplanes friuliensis DSM 7358 putative ABC transporter substrate-binding protein YP_008736424.1 5532391 R 1246995 CDS YP_008736425.1 556568000 17445774 complement(5533651..5535141) 1 NC_022657.1 COG2160 L-arabinose isomerase; L-arabinose isomerase 5535141 17445774 AFR_25540 Actinoplanes friuliensis DSM 7358 L-arabinose isomerase YP_008736425.1 5533651 R 1246995 CDS YP_008736426.1 556568001 17445775 complement(5535138..5535812) 1 NC_022657.1 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases; L-ribulose-5-phosphate 4-epimerase 5535812 17445775 AFR_25545 Actinoplanes friuliensis DSM 7358 L-ribulose-5-phosphate 4-epimerase YP_008736426.1 5535138 R 1246995 CDS YP_008736427.1 556568002 17445776 complement(5535809..5537443) 1 NC_022657.1 COG1069 Ribulose kinase; ribulokinase 5537443 17445776 AFR_25550 Actinoplanes friuliensis DSM 7358 ribulokinase YP_008736427.1 5535809 R 1246995 CDS YP_008736428.1 556568003 17445777 complement(5537581..5538564) 1 NC_022657.1 COG1609 Transcriptional regulators; LacI family transcriptional regulator 5538564 17445777 AFR_25555 Actinoplanes friuliensis DSM 7358 LacI family transcriptional regulator YP_008736428.1 5537581 R 1246995 CDS YP_008736429.1 556568004 17445778 5538753..5540141 1 NC_022657.1 COG4320 Uncharacterized protein conserved in bacteria; hypothetical protein 5540141 17445778 AFR_25560 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736429.1 5538753 D 1246995 CDS YP_008736430.1 556568005 17445779 5540138..5540548 1 NC_022657.1 hypothetical protein 5540548 17445779 AFR_25565 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736430.1 5540138 D 1246995 CDS YP_008736431.1 556568006 17445780 complement(5540559..5541482) 1 NC_022657.1 hypothetical protein 5541482 17445780 AFR_25570 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736431.1 5540559 R 1246995 CDS YP_008736432.1 556568007 17445781 5541613..5542944 1 NC_022657.1 hypothetical protein 5542944 17445781 AFR_25575 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736432.1 5541613 D 1246995 CDS YP_008736433.1 556568008 17445782 5542954..5543922 1 NC_022657.1 COG1741 Pirin-related protein; pirin 5543922 17445782 AFR_25580 Actinoplanes friuliensis DSM 7358 pirin YP_008736433.1 5542954 D 1246995 CDS YP_008736434.1 556568009 17445783 5544020..5544457 1 NC_022657.1 hypothetical protein 5544457 17445783 AFR_25585 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736434.1 5544020 D 1246995 CDS YP_008736435.1 556568010 17445784 5545319..5551315 1 NC_022657.1 hypothetical protein 5551315 17445784 AFR_25590 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736435.1 5545319 D 1246995 CDS YP_008736436.1 556568011 17445785 complement(5551272..5552318) 1 NC_022657.1 COG2199 FOG: GGDEF domain; putative signaling protein 5552318 17445785 AFR_25595 Actinoplanes friuliensis DSM 7358 putative signaling protein YP_008736436.1 5551272 R 1246995 CDS YP_008736437.1 556568012 17445786 complement(5552407..5553288) 1 NC_022657.1 COG5006 Predicted permease, DMT superfamily; ywfM-like transporter 5553288 17445786 AFR_25600 Actinoplanes friuliensis DSM 7358 ywfM-like transporter YP_008736437.1 5552407 R 1246995 CDS YP_008736438.1 556568013 17445787 complement(5553285..5554469) 1 NC_022657.1 COG0577 ABC-type antimicrobial peptide transport system, permease component; putative permease 5554469 17445787 AFR_25605 Actinoplanes friuliensis DSM 7358 putative permease YP_008736438.1 5553285 R 1246995 CDS YP_008736439.1 556568014 17445788 complement(5554466..5555176) 1 NC_022657.1 COG1136 ABC-type antimicrobial peptide transport system, ATPase component; putative ABC transporter ATP-binding protein 5555176 17445788 AFR_25610 Actinoplanes friuliensis DSM 7358 putative ABC transporter ATP-binding protein YP_008736439.1 5554466 R 1246995 CDS YP_008736440.1 556568015 17445789 complement(5555173..5556492) 1 NC_022657.1 COG0845 Membrane-fusion protein; hypothetical protein 5556492 17445789 AFR_25615 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736440.1 5555173 R 1246995 CDS YP_008736441.1 556568016 17445790 5556799..5557020 1 NC_022657.1 hypothetical protein 5557020 17445790 AFR_25620 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736441.1 5556799 D 1246995 CDS YP_008736442.1 556568017 17445791 complement(5557094..5557849) 1 NC_022657.1 COG1376 Uncharacterized protein conserved in bacteria; hypothetical protein 5557849 17445791 AFR_25625 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736442.1 5557094 R 1246995 CDS YP_008736443.1 556568018 17445792 complement(5557948..5558826) 1 NC_022657.1 COG2340 Uncharacterized protein with SCP/PR1 domains; hypothetical protein 5558826 17445792 AFR_25630 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736443.1 5557948 R 1246995 CDS YP_008736444.1 556568019 17445793 5559100..5560692 1 NC_022657.1 acyltransferase 3 5560692 17445793 AFR_25635 Actinoplanes friuliensis DSM 7358 acyltransferase 3 YP_008736444.1 5559100 D 1246995 CDS YP_008736445.1 556568020 17445794 complement(5560753..5561688) 1 NC_022657.1 hypothetical protein 5561688 17445794 AFR_25640 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736445.1 5560753 R 1246995 CDS YP_008736446.1 556568021 17445795 complement(5561773..5562441) 1 NC_022657.1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; two component LuxR family transcriptional regulator 5562441 17445795 AFR_25645 Actinoplanes friuliensis DSM 7358 two component LuxR family transcriptional regulator YP_008736446.1 5561773 R 1246995 CDS YP_008736447.1 556568022 17445796 complement(5563087..5564271) 1 NC_022657.1 COG4585 Signal transduction histidine kinase; histidine kinase, dimerization and phosphoacceptor region 5564271 17445796 AFR_25650 Actinoplanes friuliensis DSM 7358 histidine kinase, dimerization and phosphoacceptor region YP_008736447.1 5563087 R 1246995 CDS YP_008736448.1 556568023 17445797 complement(5564283..5566700) 1 NC_022657.1 COG0577 ABC-type antimicrobial peptide transport system, permease component; lysophospholipase L1 biosynthesis ABC transporter permease 5566700 17445797 AFR_25655 Actinoplanes friuliensis DSM 7358 lysophospholipase L1 biosynthesis ABC transporter permease YP_008736448.1 5564283 R 1246995 CDS YP_008736449.1 556568024 17445798 complement(5566730..5567464) 1 NC_022657.1 COG1136 ABC-type antimicrobial peptide transport system, ATPase component; ABC transporter ATP-binding protein 5567464 17445798 AFR_25660 Actinoplanes friuliensis DSM 7358 ABC transporter ATP-binding protein YP_008736449.1 5566730 R 1246995 CDS YP_008736450.1 556568025 17445799 5567641..5568114 1 NC_022657.1 COG0835 Chemotaxis signal transduction protein; Chemotaxis protein cheV 5568114 17445799 AFR_25665 Actinoplanes friuliensis DSM 7358 Chemotaxis protein cheV YP_008736450.1 5567641 D 1246995 CDS YP_008736451.1 556568026 17445800 5568111..5569508 1 NC_022657.1 COG1352 Methylase of chemotaxis methyl-accepting proteins; putative MCP methyltransferase CheR with TPR domain 5569508 17445800 AFR_25670 Actinoplanes friuliensis DSM 7358 putative MCP methyltransferase CheR with TPR domain YP_008736451.1 5568111 D 1246995 CDS YP_008736452.1 556568027 17445801 5569520..5570044 1 NC_022657.1 COG0835 Chemotaxis signal transduction protein; putative chemotaxis signal transduction protein CheW 5570044 17445801 AFR_25675 Actinoplanes friuliensis DSM 7358 putative chemotaxis signal transduction protein CheW YP_008736452.1 5569520 D 1246995 CDS YP_008736453.1 556568028 17445802 5570050..5571516 1 NC_022657.1 COG0840 Methyl-accepting chemotaxis protein; putative methyl-accepting chemotaxis protein 5571516 17445802 AFR_25680 Actinoplanes friuliensis DSM 7358 putative methyl-accepting chemotaxis protein YP_008736453.1 5570050 D 1246995 CDS YP_008736454.1 556568029 17445803 5571516..5573696 1 NC_022657.1 COG0643 Chemotaxis protein histidine kinase and related kinases; two-component system, chemotaxis family, sensor kinase CheA 5573696 17445803 AFR_25685 Actinoplanes friuliensis DSM 7358 two-component system, chemotaxis family, sensor kinase CheA YP_008736454.1 5571516 D 1246995 CDS YP_008736455.1 556568030 17445804 5573693..5574778 1 NC_022657.1 COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain; two-component system, chemotaxis family, response regulator CheB 5574778 17445804 AFR_25690 Actinoplanes friuliensis DSM 7358 two-component system, chemotaxis family, response regulator CheB YP_008736455.1 5573693 D 1246995 CDS YP_008736456.1 556568031 17445805 5574775..5576766 1 NC_022657.1 COG0784 FOG: CheY-like receiver; multi-sensor signal transduction histidine kinase 5576766 17445805 AFR_25695 Actinoplanes friuliensis DSM 7358 multi-sensor signal transduction histidine kinase YP_008736456.1 5574775 D 1246995 CDS YP_008736457.1 556568032 17445806 complement(5576809..5578953) 1 NC_022657.1 COG5479 Uncharacterized protein potentially involved in peptidoglycan biosynthesis; putative N-acetylmuramoyl-L-alanine amidase 5578953 17445806 AFR_25700 Actinoplanes friuliensis DSM 7358 putative N-acetylmuramoyl-L-alanine amidase YP_008736457.1 5576809 R 1246995 CDS YP_008736458.1 556568033 17445807 complement(5579163..5579792) 1 NC_022657.1 hypothetical protein 5579792 17445807 AFR_25705 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736458.1 5579163 R 1246995 CDS YP_008736459.1 556568034 17445808 5580245..5580532 1 NC_022657.1 hypothetical protein 5580532 17445808 AFR_25710 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736459.1 5580245 D 1246995 CDS YP_008736460.1 556568035 17445809 complement(5580517..5581446) 1 NC_022657.1 COG0657 Esterase/lipase; alpha/beta hydrolase 5581446 17445809 AFR_25715 Actinoplanes friuliensis DSM 7358 alpha/beta hydrolase YP_008736460.1 5580517 R 1246995 CDS YP_008736461.1 556568036 17445810 complement(5581486..5584050) 1 NC_022657.1 COG0577 ABC-type antimicrobial peptide transport system, permease component; Macrolide export ATP-binding/permease protein macB 1 5584050 17445810 AFR_25720 Actinoplanes friuliensis DSM 7358 Macrolide export ATP-binding/permease protein macB 1 YP_008736461.1 5581486 R 1246995 CDS YP_008736462.1 556568037 17445811 complement(5584047..5584835) 1 NC_022657.1 COG1136 ABC-type antimicrobial peptide transport system, ATPase component; putative ABC transporter ATP-binding protein 5584835 17445811 AFR_25725 Actinoplanes friuliensis DSM 7358 putative ABC transporter ATP-binding protein YP_008736462.1 5584047 R 1246995 CDS YP_008736463.1 556568038 17445812 5584998..5586170 1 NC_022657.1 COG4585 Signal transduction histidine kinase; Sensor histidine kinase yxjM 5586170 17445812 AFR_25730 Actinoplanes friuliensis DSM 7358 Sensor histidine kinase yxjM YP_008736463.1 5584998 D 1246995 CDS YP_008736464.1 556568039 17445813 5586167..5586805 1 NC_022657.1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; Transcriptional regulatory protein desR 5586805 17445813 AFR_25735 Actinoplanes friuliensis DSM 7358 Transcriptional regulatory protein desR YP_008736464.1 5586167 D 1246995 CDS YP_008736465.1 556568040 17445814 complement(5586859..5588046) 1 NC_022657.1 hypothetical protein 5588046 17445814 AFR_25740 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736465.1 5586859 R 1246995 CDS YP_008736466.1 556568041 17445815 5588091..5588744 1 NC_022657.1 COG4122 Predicted O-methyltransferase; O-methyltransferase 5588744 17445815 AFR_25745 Actinoplanes friuliensis DSM 7358 O-methyltransferase YP_008736466.1 5588091 D 1246995 CDS YP_008736467.1 556568042 17445816 complement(5588725..5589258) 1 NC_022657.1 COG3981 Predicted acetyltransferase; putative GCN5-related N-acetyltransferase 5589258 17445816 AFR_25750 Actinoplanes friuliensis DSM 7358 putative GCN5-related N-acetyltransferase YP_008736467.1 5588725 R 1246995 CDS YP_008736468.1 556568043 17445817 complement(5589276..5589776) 1 NC_022657.1 COG1846 Transcriptional regulators; MarR family transcriptional regulator 5589776 17445817 AFR_25755 Actinoplanes friuliensis DSM 7358 MarR family transcriptional regulator YP_008736468.1 5589276 R 1246995 CDS YP_008736469.1 556568044 17445818 complement(5589822..5590403) 1 NC_022657.1 hypothetical protein 5590403 17445818 AFR_25760 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736469.1 5589822 R 1246995 CDS YP_008736470.1 556568045 17445819 complement(5590439..5591185) 1 NC_022657.1 COG3397 Uncharacterized protein conserved in bacteria; putative secreted chitin-binding protein 5591185 17445819 AFR_25765 Actinoplanes friuliensis DSM 7358 putative secreted chitin-binding protein YP_008736470.1 5590439 R 1246995 CDS YP_008736471.1 556568046 17445820 complement(5591362..5593917) 1 NC_022657.1 COG2199 FOG: GGDEF domain; putative diguanylate cyclase/phosphodiesterase with PAS sensor 5593917 17445820 AFR_25770 Actinoplanes friuliensis DSM 7358 putative diguanylate cyclase/phosphodiesterase with PAS sensor YP_008736471.1 5591362 R 1246995 CDS YP_008736472.1 556568047 17445821 5594061..5595317 1 NC_022657.1 COG2200 FOG: EAL domain; hypothetical protein 5595317 17445821 AFR_25775 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736472.1 5594061 D 1246995 CDS YP_008736473.1 556568048 17445822 5595410..5596228 1 NC_022657.1 COG0726 Predicted xylanase/chitin deacetylase; putative polysaccharide deacetylase 5596228 17445822 AFR_25780 Actinoplanes friuliensis DSM 7358 putative polysaccharide deacetylase YP_008736473.1 5595410 D 1246995 CDS YP_008736474.1 556568049 17445823 complement(5596220..5597635) 1 NC_022657.1 COG1396 Predicted transcriptional regulators; putative DNA-binding protein 5597635 17445823 AFR_25785 Actinoplanes friuliensis DSM 7358 putative DNA-binding protein YP_008736474.1 5596220 R 1246995 CDS YP_008736475.1 556568050 17445824 5597778..5599067 1 NC_022657.1 COG2224 Isocitrate lyase; isocitrate lyase 5599067 17445824 AFR_25790 Actinoplanes friuliensis DSM 7358 isocitrate lyase YP_008736475.1 5597778 D 1246995 CDS YP_008736476.1 556568051 17445825 5599067..5600665 1 NC_022657.1 COG2225 Malate synthase; putative malate synthase 5600665 17445825 AFR_25795 Actinoplanes friuliensis DSM 7358 putative malate synthase YP_008736476.1 5599067 D 1246995 CDS YP_008736477.1 556568052 17445826 5600955..5602433 1 NC_022657.1 COG0246 Mannitol-1-phosphate/altronate dehydrogenases; mannitol-1-phosphate/altronate dehydrogenase 5602433 17445826 AFR_25800 Actinoplanes friuliensis DSM 7358 mannitol-1-phosphate/altronate dehydrogenase YP_008736477.1 5600955 D 1246995 CDS YP_008736478.1 556568053 17445827 5602532..5603323 1 NC_022657.1 putative pectate lyase 5603323 17445827 AFR_25805 Actinoplanes friuliensis DSM 7358 putative pectate lyase YP_008736478.1 5602532 D 1246995 CDS YP_008736479.1 556568054 17445828 complement(5603371..5603853) 1 NC_022657.1 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; hypothetical protein 5603853 17445828 AFR_25810 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736479.1 5603371 R 1246995 CDS YP_008736480.1 556568055 17445829 complement(5604155..5604799) 1 NC_022657.1 hypothetical protein 5604799 17445829 AFR_25815 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736480.1 5604155 R 1246995 CDS YP_008736481.1 556568056 17445830 complement(5604789..5605343) 1 NC_022657.1 hypothetical protein 5605343 17445830 AFR_25820 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736481.1 5604789 R 1246995 CDS YP_008736482.1 556568057 17445831 complement(5605353..5607572) 1 NC_022657.1 putative glycosyl hydrolase 5607572 17445831 AFR_25825 Actinoplanes friuliensis DSM 7358 putative glycosyl hydrolase YP_008736482.1 5605353 R 1246995 CDS YP_008736483.1 556568058 17445832 5607681..5608256 1 NC_022657.1 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins; putative N-acetyltransferase 5608256 17445832 AFR_25830 Actinoplanes friuliensis DSM 7358 putative N-acetyltransferase YP_008736483.1 5607681 D 1246995 CDS YP_008736484.1 556568059 17445833 5608253..5608780 1 NC_022657.1 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; NUDIX hydrolase 5608780 17445833 AFR_25835 Actinoplanes friuliensis DSM 7358 NUDIX hydrolase YP_008736484.1 5608253 D 1246995 CDS YP_008736485.1 556568060 17445834 5608841..5609845 1 NC_022657.1 hypothetical protein 5609845 17445834 AFR_25840 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736485.1 5608841 D 1246995 CDS YP_008736486.1 556568061 17445835 5609913..5613044 1 NC_022657.1 COG0443 Molecular chaperone; hypothetical protein 5613044 17445835 AFR_25845 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736486.1 5609913 D 1246995 CDS YP_008736487.1 556568062 17445836 complement(5613026..5613682) 1 NC_022657.1 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins; GCN5-like N-acetyltransferase 5613682 17445836 AFR_25850 Actinoplanes friuliensis DSM 7358 GCN5-like N-acetyltransferase YP_008736487.1 5613026 R 1246995 CDS YP_008736488.1 556568063 17445837 complement(5613679..5614359) 1 NC_022657.1 hypothetical protein 5614359 17445837 AFR_25855 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736488.1 5613679 R 1246995 CDS YP_008736489.1 556568064 17445838 complement(5614747..5616165) 1 NC_022657.1 COG0699 Predicted GTPases (dynamin-related); hypothetical protein 5616165 17445838 AFR_25860 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736489.1 5614747 R 1246995 CDS YP_008736490.1 556568065 17445839 complement(5616168..5617916) 1 NC_022657.1 COG0699 Predicted GTPases (dynamin-related); hypothetical protein 5617916 17445839 AFR_25865 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736490.1 5616168 R 1246995 CDS YP_008736491.1 556568066 17445840 complement(5617957..5619039) 1 NC_022657.1 COG1275 Tellurite resistance protein and related permeases; C4-dicarboxylate transporter/malic acid transport protein 5619039 17445840 AFR_25870 Actinoplanes friuliensis DSM 7358 C4-dicarboxylate transporter/malic acid transport protein YP_008736491.1 5617957 R 1246995 CDS YP_008736492.1 556568067 17445841 5619102..5620001 1 NC_022657.1 COG0583 Transcriptional regulator; putative transcriptional regulator 5620001 17445841 AFR_25875 Actinoplanes friuliensis DSM 7358 putative transcriptional regulator YP_008736492.1 5619102 D 1246995 CDS YP_008736493.1 556568068 17445842 complement(5620044..5621057) 1 NC_022657.1 COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases; alcohol dehydrogenase superfamily protein 5621057 17445842 AFR_25880 Actinoplanes friuliensis DSM 7358 alcohol dehydrogenase superfamily protein YP_008736493.1 5620044 R 1246995 CDS YP_008736494.1 556568069 17445843 5621178..5621609 1 NC_022657.1 COG1733 Predicted transcriptional regulators; putative HxlR-family transcriptional regulator 5621609 17445843 AFR_25885 Actinoplanes friuliensis DSM 7358 putative HxlR-family transcriptional regulator YP_008736494.1 5621178 D 1246995 CDS YP_008736495.1 556568070 17445844 5621800..5624484 1 NC_022657.1 COG2133 Glucose/sorbosone dehydrogenases; hypothetical protein 5624484 17445844 AFR_25890 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736495.1 5621800 D 1246995 CDS YP_008736496.1 556568071 17445845 5624609..5626195 1 NC_022657.1 hypothetical protein 5626195 17445845 AFR_25895 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736496.1 5624609 D 1246995 CDS YP_008736497.1 556568072 17445846 complement(5626251..5627015) 1 NC_022657.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); hydrolase or acyltransferase (alpha/beta hydrolase superfamily) protein 5627015 17445846 AFR_25900 Actinoplanes friuliensis DSM 7358 hydrolase or acyltransferase (alpha/beta hydrolase superfamily) protein YP_008736497.1 5626251 R 1246995 CDS YP_008736498.1 556568073 17445847 5627080..5627799 1 NC_022657.1 hypothetical protein 5627799 17445847 AFR_25905 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736498.1 5627080 D 1246995 CDS YP_008736499.1 556568074 17445848 5627851..5629458 1 NC_022657.1 COG1960 Acyl-CoA dehydrogenases; acyl-CoA dehydrogenase domain-containing protein 5629458 17445848 AFR_25910 Actinoplanes friuliensis DSM 7358 acyl-CoA dehydrogenase domain-containing protein YP_008736499.1 5627851 D 1246995 CDS YP_008736500.1 556568075 17445849 5629520..5631733 1 NC_022657.1 COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain; putative signaling protein 5631733 17445849 AFR_25915 Actinoplanes friuliensis DSM 7358 putative signaling protein YP_008736500.1 5629520 D 1246995 CDS YP_008736501.1 556568076 17445850 5631812..5634001 1 NC_022657.1 COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain; putative signaling protein 5634001 17445850 AFR_25920 Actinoplanes friuliensis DSM 7358 putative signaling protein YP_008736501.1 5631812 D 1246995 CDS YP_008736502.1 556568077 17445851 5634044..5635537 1 NC_022657.1 ATP/GTP binding protein 5635537 17445851 AFR_25925 Actinoplanes friuliensis DSM 7358 ATP/GTP binding protein YP_008736502.1 5634044 D 1246995 CDS YP_008736503.1 556568078 17445852 5635534..5635980 1 NC_022657.1 COG0495 Leucyl-tRNA synthetase; hypothetical protein 5635980 17445852 AFR_25930 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736503.1 5635534 D 1246995 CDS YP_008736504.1 556568079 17445853 5636082..5636897 1 NC_022657.1 COG0457 FOG: TPR repeat; tetratricopeptide domain-containing protein 5636897 17445853 AFR_25935 Actinoplanes friuliensis DSM 7358 tetratricopeptide domain-containing protein YP_008736504.1 5636082 D 1246995 CDS YP_008736505.1 556568080 17445854 complement(5636901..5638346) 1 NC_022657.1 COG0464 ATPases of the AAA+ class; putative AAA ATPase 5638346 17445854 AFR_25940 Actinoplanes friuliensis DSM 7358 putative AAA ATPase YP_008736505.1 5636901 R 1246995 CDS YP_008736506.1 556568081 17445855 complement(5638413..5639132) 1 NC_022657.1 hypothetical protein 5639132 17445855 AFR_25945 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736506.1 5638413 R 1246995 CDS YP_008736507.1 556568082 17445856 5639535..5642492 1 NC_022657.1 COG1396 Predicted transcriptional regulators; SARP family transcriptional regulator 5642492 17445856 AFR_25950 Actinoplanes friuliensis DSM 7358 SARP family transcriptional regulator YP_008736507.1 5639535 D 1246995 CDS YP_008736508.1 556568083 17445857 complement(5642477..5643523) 1 NC_022657.1 COG0438 Glycosyltransferase; Glycosyltransferase 5643523 17445857 AFR_25955 Actinoplanes friuliensis DSM 7358 Glycosyltransferase YP_008736508.1 5642477 R 1246995 CDS YP_008736509.1 556568084 17445858 complement(5643520..5644356) 1 NC_022657.1 COG0388 Predicted amidohydrolase; nitrilase 5644356 17445858 AFR_25960 Actinoplanes friuliensis DSM 7358 nitrilase YP_008736509.1 5643520 R 1246995 CDS YP_008736510.1 556568085 17445859 complement(5644360..5645184) 1 NC_022657.1 COG0388 Predicted amidohydrolase; hypothetical protein 5645184 17445859 AFR_25965 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736510.1 5644360 R 1246995 CDS YP_008736511.1 556568086 17445860 complement(5645190..5646542) 1 NC_022657.1 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; N-acetyltransferase GCN5 5646542 17445860 AFR_25970 Actinoplanes friuliensis DSM 7358 N-acetyltransferase GCN5 YP_008736511.1 5645190 R 1246995 CDS YP_008736512.1 556568087 17445861 complement(5646539..5647591) 1 NC_022657.1 COG2516 Biotin synthase-related enzyme; radical SAM protein 5647591 17445861 AFR_25975 Actinoplanes friuliensis DSM 7358 radical SAM protein YP_008736512.1 5646539 R 1246995 CDS YP_008736513.1 556568088 17445862 complement(5647591..5648103) 1 NC_022657.1 COG2044 Predicted peroxiredoxins; hypothetical protein 5648103 17445862 AFR_25980 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736513.1 5647591 R 1246995 CDS YP_008736514.1 556568089 17445863 complement(5648113..5648913) 1 NC_022657.1 COG2159 Predicted metal-dependent hydrolase of the TIM-barrel fold; hypothetical protein 5648913 17445863 AFR_25985 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736514.1 5648113 R 1246995 CDS YP_008736515.1 556568090 17445864 complement(5648910..5650232) 1 NC_022657.1 COG2072 Predicted flavoprotein involved in K+ transport; hypothetical protein 5650232 17445864 AFR_25990 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736515.1 5648910 R 1246995 CDS YP_008736516.1 556568091 17445865 complement(5650229..5650507) 1 NC_022657.1 hypothetical protein 5650507 17445865 AFR_25995 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736516.1 5650229 R 1246995 CDS YP_008736517.1 556568092 17445866 complement(5650646..5651698) 1 NC_022657.1 hypothetical protein 5651698 17445866 AFR_26000 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736517.1 5650646 R 1246995 CDS YP_008736518.1 556568093 17445867 complement(5651773..5652912) 1 NC_022657.1 Endoglucanase E-4 5652912 17445867 AFR_26005 Actinoplanes friuliensis DSM 7358 Endoglucanase E-4 YP_008736518.1 5651773 R 1246995 CDS YP_008736519.1 556568094 17445868 complement(5652906..5654219) 1 NC_022657.1 COG5297 Cellobiohydrolase A (1,4-beta-cellobiosidase A); cellobiohydrolase A (1 4-beta-cellobiosidase A)-like protein 5654219 17445868 AFR_26010 Actinoplanes friuliensis DSM 7358 cellobiohydrolase A (1 4-beta-cellobiosidase A)-like protein YP_008736519.1 5652906 R 1246995 CDS YP_008736520.1 556568095 17445869 complement(5654400..5655080) 1 NC_022657.1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; LuxR family transcriptional regulator 5655080 17445869 AFR_26015 Actinoplanes friuliensis DSM 7358 LuxR family transcriptional regulator YP_008736520.1 5654400 R 1246995 CDS YP_008736521.1 556568096 17445870 complement(5655077..5656267) 1 NC_022657.1 COG4585 Signal transduction histidine kinase; histidine kinase 5656267 17445870 AFR_26020 Actinoplanes friuliensis DSM 7358 histidine kinase YP_008736521.1 5655077 R 1246995 CDS YP_008736522.1 556568097 17445871 5656443..5658617 1 NC_022657.1 COG2409 Predicted drug exporters of the RND superfamily; transmembrane transport protein 5658617 17445871 AFR_26025 Actinoplanes friuliensis DSM 7358 transmembrane transport protein YP_008736522.1 5656443 D 1246995 CDS YP_008736523.1 556568098 17445872 5658687..5659493 1 NC_022657.1 COG0477 Permeases of the major facilitator superfamily; hypothetical protein 5659493 17445872 AFR_26030 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736523.1 5658687 D 1246995 CDS YP_008736524.1 556568099 17445873 5659557..5659976 1 NC_022657.1 hypothetical protein 5659976 17445873 AFR_26035 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736524.1 5659557 D 1246995 CDS YP_008736525.1 556568100 17445874 complement(5660036..5660290) 1 NC_022657.1 hypothetical protein 5660290 17445874 AFR_26040 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736525.1 5660036 R 1246995 CDS YP_008736526.1 556568101 17445875 5660199..5660396 1 NC_022657.1 hypothetical protein 5660396 17445875 AFR_26045 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736526.1 5660199 D 1246995 CDS YP_008736527.1 556568102 17445876 complement(5660611..5660835) 1 NC_022657.1 hypothetical protein 5660835 17445876 AFR_26050 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736527.1 5660611 R 1246995 CDS YP_008736528.1 556568103 17445877 complement(5661006..5661686) 1 NC_022657.1 COG1280 Putative threonine efflux protein; lysine exporter protein LysE/YggA 5661686 17445877 AFR_26055 Actinoplanes friuliensis DSM 7358 lysine exporter protein LysE/YggA YP_008736528.1 5661006 R 1246995 CDS YP_008736529.1 556568104 17445878 5661713..5662864 1 NC_022657.1 hypothetical protein 5662864 17445878 AFR_26060 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736529.1 5661713 D 1246995 CDS YP_008736530.1 556568105 17445879 5662926..5663306 1 NC_022657.1 COG0422 Thiamine biosynthesis protein ThiC; hypothetical protein 5663306 17445879 AFR_26065 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736530.1 5662926 D 1246995 CDS YP_008736531.1 556568106 17445880 5663455..5665827 1 NC_022657.1 COG2304 Uncharacterized protein containing a von Willebrand factor type A (vWA) domain; hypothetical protein 5665827 17445880 AFR_26070 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736531.1 5663455 D 1246995 CDS YP_008736532.1 556568107 17445881 5665850..5667094 1 NC_022657.1 COG1653 ABC-type sugar transport system, periplasmic component; putative ABC transporter substrate-binding protein 5667094 17445881 AFR_26075 Actinoplanes friuliensis DSM 7358 putative ABC transporter substrate-binding protein YP_008736532.1 5665850 D 1246995 CDS YP_008736533.1 556568108 17445882 complement(5667114..5668598) 1 NC_022657.1 COG0308 Aminopeptidase N; glutamyl aminopeptidase 5668598 17445882 AFR_26080 Actinoplanes friuliensis DSM 7358 glutamyl aminopeptidase YP_008736533.1 5667114 R 1246995 CDS YP_008736534.1 556568109 17445883 complement(5668649..5669323) 1 NC_022657.1 COG3548 Predicted integral membrane protein; hypothetical protein 5669323 17445883 AFR_26085 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736534.1 5668649 R 1246995 CDS YP_008736535.1 556568110 17445884 complement(5670638..5670832) 1 NC_022657.1 COG1141 Ferredoxin; putative 3Fe-4S ferredoxin 5670832 17445884 AFR_26100 Actinoplanes friuliensis DSM 7358 putative 3Fe-4S ferredoxin YP_008736535.1 5670638 R 1246995 CDS YP_008736536.1 556568111 17445885 5671058..5671810 1 NC_022657.1 COG1129 ABC-type sugar transport system, ATPase component; hypothetical protein 5671810 17445885 AFR_26105 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736536.1 5671058 D 1246995 CDS YP_008736537.1 556568112 17445886 complement(5671774..5672862) 1 NC_022657.1 COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit; hypothetical protein 5672862 17445886 AFR_26110 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736537.1 5671774 R 1246995 CDS YP_008736538.1 556568113 17445887 complement(5672856..5674097) 1 NC_022657.1 COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily; mandelate racemase/muconate lactonizing protein 5674097 17445887 AFR_26115 Actinoplanes friuliensis DSM 7358 mandelate racemase/muconate lactonizing protein YP_008736538.1 5672856 R 1246995 CDS YP_008736539.1 556568114 17445888 complement(5674118..5674999) 1 NC_022657.1 COG0395 ABC-type sugar transport system, permease component; sugar transport system, permease 5674999 17445888 AFR_26120 Actinoplanes friuliensis DSM 7358 sugar transport system, permease YP_008736539.1 5674118 R 1246995 CDS YP_008736540.1 556568115 17445889 complement(5674996..5675931) 1 NC_022657.1 COG1175 ABC-type sugar transport systems, permease components; sugar transport system, permease 5675931 17445889 AFR_26125 Actinoplanes friuliensis DSM 7358 sugar transport system, permease YP_008736540.1 5674996 R 1246995 CDS YP_008736541.1 556568116 17445890 complement(5675928..5677223) 1 NC_022657.1 COG1653 ABC-type sugar transport system, periplasmic component; family 1 extracellular solute-binding protein 5677223 17445890 AFR_26130 Actinoplanes friuliensis DSM 7358 family 1 extracellular solute-binding protein YP_008736541.1 5675928 R 1246995 CDS YP_008736542.1 556568117 17445891 5677463..5678191 1 NC_022657.1 COG1414 Transcriptional regulator; IclR family transcriptional regulator 5678191 17445891 AFR_26135 Actinoplanes friuliensis DSM 7358 IclR family transcriptional regulator YP_008736542.1 5677463 D 1246995 CDS YP_008736543.1 556568118 17445892 complement(5678188..5679012) 1 NC_022657.1 COG0451 Nucleoside-diphosphate-sugar epimerases; NAD-dependent epimerase/dehydratase 5679012 17445892 AFR_26140 Actinoplanes friuliensis DSM 7358 NAD-dependent epimerase/dehydratase YP_008736543.1 5678188 R 1246995 CDS YP_008736544.1 556568119 17445893 5679161..5680054 1 NC_022657.1 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases; 2-hydroxy-3-oxopropionate reductase 5680054 17445893 AFR_26145 Actinoplanes friuliensis DSM 7358 2-hydroxy-3-oxopropionate reductase YP_008736544.1 5679161 D 1246995 CDS YP_008736545.1 556568120 17445894 5680047..5680802 1 NC_022657.1 COG3836 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase; 2-dehydro-3-deoxyglucarate aldolase 5680802 17445894 AFR_26150 Actinoplanes friuliensis DSM 7358 2-dehydro-3-deoxyglucarate aldolase YP_008736545.1 5680047 D 1246995 CDS YP_008736546.1 556568121 17445895 complement(5680875..5683412) 1 NC_022657.1 COG4249 Uncharacterized protein containing caspase domain; caspase-related protein 5683412 17445895 AFR_26155 Actinoplanes friuliensis DSM 7358 caspase-related protein YP_008736546.1 5680875 R 1246995 CDS YP_008736547.1 556568122 17445896 complement(5683415..5683786) 1 NC_022657.1 hypothetical protein 5683786 17445896 AFR_26160 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736547.1 5683415 R 1246995 CDS YP_008736548.1 556568123 17445897 complement(5683918..5687793) 1 NC_022657.1 COG3828 Uncharacterized protein conserved in bacteria; glucose/sorbosone dehydrogenase 5687793 17445897 AFR_26165 Actinoplanes friuliensis DSM 7358 glucose/sorbosone dehydrogenase YP_008736548.1 5683918 R 1246995 CDS YP_008736549.1 556568124 17445898 complement(5688114..5688536) 1 NC_022657.1 COG1846 Transcriptional regulators; MarR family transcriptional regulator 5688536 17445898 AFR_26170 Actinoplanes friuliensis DSM 7358 MarR family transcriptional regulator YP_008736549.1 5688114 R 1246995 CDS YP_008736550.1 556568125 17445899 5688610..5689272 1 NC_022657.1 hypothetical protein 5689272 17445899 AFR_26175 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736550.1 5688610 D 1246995 CDS YP_008736551.1 556568126 17445900 5689311..5689514 1 NC_022657.1 hypothetical protein 5689514 17445900 AFR_26180 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736551.1 5689311 D 1246995 CDS YP_008736552.1 556568127 17445901 complement(5689621..5690364) 1 NC_022657.1 Rieske (2Fe-2S) iron-sulfur domain-containing protein 5690364 17445901 AFR_26185 Actinoplanes friuliensis DSM 7358 Rieske (2Fe-2S) iron-sulfur domain-containing protein YP_008736552.1 5689621 R 1246995 CDS YP_008736553.1 556568128 17445902 5690413..5691255 1 NC_022657.1 COG3342 Uncharacterized conserved protein; hypothetical protein 5691255 17445902 AFR_26190 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736553.1 5690413 D 1246995 CDS YP_008736554.1 556568129 17445903 complement(5691259..5691900) 1 NC_022657.1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; putative two-component system response regulator 5691900 17445903 AFR_26195 Actinoplanes friuliensis DSM 7358 putative two-component system response regulator YP_008736554.1 5691259 R 1246995 CDS YP_008736555.1 556568130 17445904 complement(5691888..5693129) 1 NC_022657.1 COG4585 Signal transduction histidine kinase; putative two-component system sensor kinase 5693129 17445904 AFR_26200 Actinoplanes friuliensis DSM 7358 putative two-component system sensor kinase YP_008736555.1 5691888 R 1246995 CDS YP_008736556.1 556568131 17445905 5693241..5693987 1 NC_022657.1 COG1136 ABC-type antimicrobial peptide transport system, ATPase component; putative ABC transporter ATP-binding protein 5693987 17445905 AFR_26205 Actinoplanes friuliensis DSM 7358 putative ABC transporter ATP-binding protein YP_008736556.1 5693241 D 1246995 CDS YP_008736557.1 556568132 17445906 5693984..5696287 1 NC_022657.1 COG0577 ABC-type antimicrobial peptide transport system, permease component; putative permease 5696287 17445906 AFR_26210 Actinoplanes friuliensis DSM 7358 putative permease YP_008736557.1 5693984 D 1246995 CDS YP_008736558.1 556568133 17445907 5696379..5697926 1 NC_022657.1 COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II; putative acyl-CoA synthetase 5697926 17445907 AFR_26215 Actinoplanes friuliensis DSM 7358 putative acyl-CoA synthetase YP_008736558.1 5696379 D 1246995 CDS YP_008736559.1 556568134 17445908 5698079..5699401 1 NC_022657.1 hypothetical protein 5699401 17445908 AFR_26220 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736559.1 5698079 D 1246995 CDS YP_008736560.1 556568135 17445909 5699401..5700363 1 NC_022657.1 COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; Membrane-bound lytic murein transglycosylase F 5700363 17445909 AFR_26225 Actinoplanes friuliensis DSM 7358 Membrane-bound lytic murein transglycosylase F YP_008736560.1 5699401 D 1246995 CDS YP_008736561.1 556568136 17445910 5700369..5701565 1 NC_022657.1 hypothetical protein 5701565 17445910 AFR_26230 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736561.1 5700369 D 1246995 CDS YP_008736562.1 556568137 17445911 5701562..5703766 1 NC_022657.1 COG0515 Serine/threonine protein kinase; putative serine/threonine protein kinase 5703766 17445911 AFR_26235 Actinoplanes friuliensis DSM 7358 putative serine/threonine protein kinase YP_008736562.1 5701562 D 1246995 CDS YP_008736563.1 556568138 17445912 5703801..5704775 1 NC_022657.1 COG0631 Serine/threonine protein phosphatase; Protein kinase and PP2C-like domain-containing protein 5704775 17445912 AFR_26240 Actinoplanes friuliensis DSM 7358 Protein kinase and PP2C-like domain-containing protein YP_008736563.1 5703801 D 1246995 CDS YP_008736564.1 556568139 17445913 5704787..5706052 1 NC_022657.1 Collagen alpha-1(VII) chain 5706052 17445913 AFR_26245 Actinoplanes friuliensis DSM 7358 Collagen alpha-1(VII) chain YP_008736564.1 5704787 D 1246995 CDS YP_008736565.1 556568140 17445914 5706049..5706699 1 NC_022657.1 COG1716 FOG: FHA domain; Oxoglutarate dehydrogenase inhibitor 5706699 17445914 AFR_26250 Actinoplanes friuliensis DSM 7358 Oxoglutarate dehydrogenase inhibitor YP_008736565.1 5706049 D 1246995 CDS YP_008736566.1 556568141 17445915 5706767..5707333 1 NC_022657.1 hypothetical protein 5707333 17445915 AFR_26255 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736566.1 5706767 D 1246995 CDS YP_008736567.1 556568142 17445916 complement(5707321..5709009) 1 NC_022657.1 COG2755 Lysophospholipase L1 and related esterases; ricin B lectin 5709009 17445916 AFR_26260 Actinoplanes friuliensis DSM 7358 ricin B lectin YP_008736567.1 5707321 R 1246995 CDS YP_008736568.1 556568143 17445917 5709107..5709559 1 NC_022657.1 COG3067 Na+/H+ antiporter; hypothetical protein 5709559 17445917 AFR_26265 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736568.1 5709107 D 1246995 CDS YP_008736569.1 556568144 17445918 complement(5709560..5710342) 1 NC_022657.1 COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family; histidinol-phosphate phosphatase 5710342 17445918 AFR_26270 Actinoplanes friuliensis DSM 7358 histidinol-phosphate phosphatase YP_008736569.1 5709560 R 1246995 CDS YP_008736570.1 556568145 17445919 complement(5710352..5710699) 1 NC_022657.1 COG2764 Uncharacterized protein conserved in bacteria; glyoxalase/bleomycin resistance protein/dioxygenase 5710699 17445919 AFR_26275 Actinoplanes friuliensis DSM 7358 glyoxalase/bleomycin resistance protein/dioxygenase YP_008736570.1 5710352 R 1246995 CDS YP_008736571.1 556568146 17445920 complement(5710696..5711646) 1 NC_022657.1 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; RNA polymerase factor sigma-70 5711646 17445920 AFR_26280 Actinoplanes friuliensis DSM 7358 RNA polymerase factor sigma-70 YP_008736571.1 5710696 R 1246995 CDS YP_008736572.1 556568147 17445921 5711766..5713070 1 NC_022657.1 COG3866 Pectate lyase; putative pectate lyase 5713070 17445921 AFR_26285 Actinoplanes friuliensis DSM 7358 putative pectate lyase YP_008736572.1 5711766 D 1246995 CDS YP_008736573.1 556568148 17445922 complement(5713075..5713539) 1 NC_022657.1 COG3832 Uncharacterized conserved protein; hypothetical protein 5713539 17445922 AFR_26290 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736573.1 5713075 R 1246995 CDS YP_008736574.1 556568149 17445923 complement(5713724..5714659) 1 NC_022657.1 COG4977 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain; AraC family transcriptional regulator 5714659 17445923 AFR_26295 Actinoplanes friuliensis DSM 7358 AraC family transcriptional regulator YP_008736574.1 5713724 R 1246995 CDS YP_008736575.1 556568150 17445924 5714731..5715645 1 NC_022657.1 COG3268 Uncharacterized conserved protein; saccharopine dehydrogenase 5715645 17445924 AFR_26300 Actinoplanes friuliensis DSM 7358 saccharopine dehydrogenase YP_008736575.1 5714731 D 1246995 CDS YP_008736576.1 556568151 17445925 complement(5715629..5716444) 1 NC_022657.1 putative dioxygenase 5716444 17445925 AFR_26305 Actinoplanes friuliensis DSM 7358 putative dioxygenase YP_008736576.1 5715629 R 1246995 CDS YP_008736577.1 556568152 17445926 5716497..5717492 1 NC_022657.1 COG1609 Transcriptional regulators; putative LacI-family transcriptional regulator 5717492 17445926 AFR_26310 Actinoplanes friuliensis DSM 7358 putative LacI-family transcriptional regulator YP_008736577.1 5716497 D 1246995 CDS YP_008736578.1 556568153 17445927 complement(5717489..5717821) 1 NC_022657.1 hypothetical protein 5717821 17445927 AFR_26315 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736578.1 5717489 R 1246995 CDS YP_008736579.1 556568154 17445928 complement(5717821..5720553) 1 NC_022657.1 COG4581 Superfamily II RNA helicase; ATP-dependent RNA helicase HelY 5720553 17445928 AFR_26320 Actinoplanes friuliensis DSM 7358 ATP-dependent RNA helicase HelY YP_008736579.1 5717821 R 1246995 CDS YP_008736580.1 556568155 17445929 5720709..5721455 1 NC_022657.1 COG0637 Predicted phosphatase/phosphohexomutase; putative haloacid dehalogenase-like hydrolase 5721455 17445929 AFR_26325 Actinoplanes friuliensis DSM 7358 putative haloacid dehalogenase-like hydrolase YP_008736580.1 5720709 D 1246995 CDS YP_008736581.1 556568156 17445930 complement(5721466..5721663) 1 NC_022657.1 hypothetical protein 5721663 17445930 AFR_26330 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736581.1 5721466 R 1246995 CDS YP_008736582.1 556568157 17445931 complement(5721765..5722664) 1 NC_022657.1 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase; diacylglycerol kinase catalytic subunit 5722664 17445931 AFR_26335 Actinoplanes friuliensis DSM 7358 diacylglycerol kinase catalytic subunit YP_008736582.1 5721765 R 1246995 CDS YP_008736583.1 556568158 17445932 complement(5722689..5723636) 1 NC_022657.1 COG0805 Sec-independent protein secretion pathway component TatC; putative sec-independent protein translocase TatC 5723636 17445932 AFR_26340 Actinoplanes friuliensis DSM 7358 putative sec-independent protein translocase TatC YP_008736583.1 5722689 R 1246995 CDS YP_008736584.1 556568159 17445933 complement(5723643..5724008) 1 NC_022657.1 COG1826 Sec-independent protein secretion pathway components; twin arginine translocase protein A 5724008 tatA 17445933 tatA Actinoplanes friuliensis DSM 7358 twin arginine translocase protein A YP_008736584.1 5723643 R 1246995 CDS YP_008736585.1 556568160 17445934 complement(5724177..5724446) 1 NC_022657.1 hypothetical protein 5724446 17445934 AFR_26350 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736585.1 5724177 R 1246995 CDS YP_008736586.1 556568161 17445935 complement(5724457..5725443) 1 NC_022657.1 COG2378 Predicted transcriptional regulator; hypothetical protein 5725443 17445935 AFR_26355 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736586.1 5724457 R 1246995 CDS YP_008736587.1 556568162 17445936 complement(5725440..5726435) 1 NC_022657.1 COG2378 Predicted transcriptional regulator; hypothetical protein 5726435 17445936 AFR_26360 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736587.1 5725440 R 1246995 CDS YP_008736588.1 556568163 17445937 5726555..5727550 1 NC_022657.1 COG0053 Predicted Co/Zn/Cd cation transporters; Zinc transporter 9 5727550 17445937 AFR_26365 Actinoplanes friuliensis DSM 7358 Zinc transporter 9 YP_008736588.1 5726555 D 1246995 CDS YP_008736589.1 556568164 17445938 5727559..5728641 1 NC_022657.1 hypothetical protein 5728641 17445938 AFR_26370 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736589.1 5727559 D 1246995 CDS YP_008736590.1 556568165 17445939 complement(5729886..5730518) 1 NC_022657.1 COG4122 Predicted O-methyltransferase; caffeoyl-CoA O-methyltransferase 5730518 17445939 AFR_26375 Actinoplanes friuliensis DSM 7358 caffeoyl-CoA O-methyltransferase YP_008736590.1 5729886 R 1246995 CDS YP_008736591.1 556568166 17445940 5730581..5731072 1 NC_022657.1 COG0640 Predicted transcriptional regulators; regulatory protein ArsR 5731072 17445940 AFR_26380 Actinoplanes friuliensis DSM 7358 regulatory protein ArsR YP_008736591.1 5730581 D 1246995 CDS YP_008736592.1 556568167 17445941 complement(5731080..5731229) 1 NC_022657.1 hypothetical protein 5731229 17445941 AFR_26385 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736592.1 5731080 R 1246995 CDS YP_008736593.1 556568168 17445942 complement(5731327..5732685) 1 NC_022657.1 putative proteasome component 5732685 17445942 AFR_26390 Actinoplanes friuliensis DSM 7358 putative proteasome component YP_008736593.1 5731327 R 1246995 CDS YP_008736594.1 556568169 17445943 5732814..5733728 1 NC_022657.1 COG1088 dTDP-D-glucose 4,6-dehydratase; dTDP-glucose 4,6-dehydratase 5733728 17445943 AFR_26395 Actinoplanes friuliensis DSM 7358 dTDP-glucose 4,6-dehydratase YP_008736594.1 5732814 D 1246995 CDS YP_008736595.1 556568170 17445944 complement(5734071..5734925) 1 NC_022657.1 COG0638 20S proteasome, alpha and beta subunits; 20S proteasome subunits A and B 5734925 17445944 AFR_26400 Actinoplanes friuliensis DSM 7358 20S proteasome subunits A and B YP_008736595.1 5734071 R 1246995 CDS YP_008736596.1 556568171 17445945 complement(5734983..5735822) 1 NC_022657.1 COG0638 20S proteasome, alpha and beta subunits; 20S proteasome subunit beta 5735822 17445945 AFR_26405 Actinoplanes friuliensis DSM 7358 20S proteasome subunit beta YP_008736596.1 5734983 R 1246995 CDS YP_008736597.1 556568172 17445946 complement(5736053..5736268) 1 NC_022657.1 ubiquitin-like protein Pup 5736268 17445946 AFR_26410 Actinoplanes friuliensis DSM 7358 ubiquitin-like protein Pup YP_008736597.1 5736053 R 1246995 CDS YP_008736598.1 556568173 17445947 complement(5736362..5737879) 1 NC_022657.1 putative proteasome component 5737879 17445947 AFR_26415 Actinoplanes friuliensis DSM 7358 putative proteasome component YP_008736598.1 5736362 R 1246995 CDS YP_008736599.1 556568174 17445948 complement(5738056..5739723) 1 NC_022657.1 COG0464 ATPases of the AAA+ class; putative AAA ATPase 5739723 17445948 AFR_26420 Actinoplanes friuliensis DSM 7358 putative AAA ATPase YP_008736599.1 5738056 R 1246995 CDS YP_008736600.1 556568175 17445949 5740010..5740303 1 NC_022657.1 COG1141 Ferredoxin; ferredoxin 5740303 17445949 AFR_26425 Actinoplanes friuliensis DSM 7358 ferredoxin YP_008736600.1 5740010 D 1246995 CDS YP_008736601.1 556568176 17445950 complement(5740362..5740952) 1 NC_022657.1 hypothetical protein 5740952 17445950 AFR_26430 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736601.1 5740362 R 1246995 CDS YP_008736602.1 556568177 17445951 complement(5741028..5741975) 1 NC_022657.1 COG2519 tRNA(1-methyladenosine) methyltransferase and related methyltransferases; putative tRNA methyltransferase complex GCD14 subunit 5741975 17445951 AFR_26435 Actinoplanes friuliensis DSM 7358 putative tRNA methyltransferase complex GCD14 subunit YP_008736602.1 5741028 R 1246995 CDS YP_008736603.1 556568178 17445952 complement(5741987..5743150) 1 NC_022657.1 COG1994 Zn-dependent proteases; putative M50-family peptidase 5743150 17445952 AFR_26440 Actinoplanes friuliensis DSM 7358 putative M50-family peptidase YP_008736603.1 5741987 R 1246995 CDS YP_008736604.1 556568179 17445953 5743244..5744185 1 NC_022657.1 COG2887 RecB family exonuclease; hypothetical protein 5744185 17445953 AFR_26445 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736604.1 5743244 D 1246995 CDS YP_008736605.1 556568180 17445954 5744985..5745695 1 NC_022657.1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; two component LuxR family transcriptional regulator 5745695 17445954 AFR_26450 Actinoplanes friuliensis DSM 7358 two component LuxR family transcriptional regulator YP_008736605.1 5744985 D 1246995 CDS YP_008736606.1 556568181 17445955 complement(5745902..5746693) 1 NC_022657.1 COG3595 Uncharacterized conserved protein; hypothetical protein 5746693 17445955 AFR_26455 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736606.1 5745902 R 1246995 CDS YP_008736607.1 556568182 17445956 complement(5746718..5747209) 1 NC_022657.1 hypothetical protein 5747209 17445956 AFR_26460 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736607.1 5746718 R 1246995 CDS YP_008736608.1 556568183 17445957 5747434..5748201 1 NC_022657.1 COG1136 ABC-type antimicrobial peptide transport system, ATPase component; spermidine/putrescine import ATP-binding protein potA 5748201 17445957 AFR_26465 Actinoplanes friuliensis DSM 7358 spermidine/putrescine import ATP-binding protein potA YP_008736608.1 5747434 D 1246995 CDS YP_008736609.1 556568184 17445958 5748201..5750753 1 NC_022657.1 COG0577 ABC-type antimicrobial peptide transport system, permease component; Macrolide export ATP-binding/permease protein macB 5750753 17445958 AFR_26470 Actinoplanes friuliensis DSM 7358 Macrolide export ATP-binding/permease protein macB YP_008736609.1 5748201 D 1246995 CDS YP_008736610.1 556568185 17445959 complement(5750797..5751444) 1 NC_022657.1 COG0637 Predicted phosphatase/phosphohexomutase; putative haloacid dehalogenase-like hydrolase 5751444 17445959 AFR_26475 Actinoplanes friuliensis DSM 7358 putative haloacid dehalogenase-like hydrolase YP_008736610.1 5750797 R 1246995 CDS YP_008736611.1 556568186 17445960 complement(5751550..5752287) 1 NC_022657.1 COG2321 Predicted metalloprotease; hypothetical protein 5752287 17445960 AFR_26480 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736611.1 5751550 R 1246995 CDS YP_008736612.1 556568187 17445961 complement(5752405..5752896) 1 NC_022657.1 hypothetical protein 5752896 17445961 AFR_26485 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736612.1 5752405 R 1246995 CDS YP_008736613.1 556568188 17445962 5752943..5753686 1 NC_022657.1 COG3361 Uncharacterized conserved protein; hypothetical protein 5753686 17445962 AFR_26490 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736613.1 5752943 D 1246995 CDS YP_008736614.1 556568189 17445963 5753696..5754592 1 NC_022657.1 hypothetical protein 5754592 17445963 AFR_26495 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736614.1 5753696 D 1246995 CDS YP_008736615.1 556568190 17445964 complement(5754589..5755038) 1 NC_022657.1 COG3832 Uncharacterized conserved protein; hypothetical protein 5755038 17445964 AFR_26500 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736615.1 5754589 R 1246995 CDS YP_008736616.1 556568191 17445965 complement(5755035..5755376) 1 NC_022657.1 COG0640 Predicted transcriptional regulators; transcriptional repressor sdpR 5755376 17445965 AFR_26505 Actinoplanes friuliensis DSM 7358 transcriptional repressor sdpR YP_008736616.1 5755035 R 1246995 CDS YP_008736617.1 556568192 17445966 complement(5755449..5755994) 1 NC_022657.1 hypothetical protein 5755994 17445966 AFR_26510 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736617.1 5755449 R 1246995 CDS YP_008736618.1 556568193 17445967 complement(5756013..5756726) 1 NC_022657.1 COG0421 Spermidine synthase; hypothetical protein 5756726 17445967 AFR_26515 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736618.1 5756013 R 1246995 CDS YP_008736619.1 556568194 17445968 complement(5756723..5757421) 1 NC_022657.1 hypothetical protein 5757421 17445968 AFR_26520 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736619.1 5756723 R 1246995 CDS YP_008736620.1 556568195 17445969 complement(5757471..5758469) 1 NC_022657.1 COG0558 Phosphatidylglycerophosphate synthase; hypothetical protein 5758469 17445969 AFR_26525 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736620.1 5757471 R 1246995 CDS YP_008736621.1 556568196 17445970 5758729..5759277 1 NC_022657.1 COG0634 Hypoxanthine-guanine phosphoribosyltransferase; hypoxanthine phosphoribosyltransferase 5759277 17445970 AFR_26530 Actinoplanes friuliensis DSM 7358 hypoxanthine phosphoribosyltransferase YP_008736621.1 5758729 D 1246995 CDS YP_008736622.1 556568197 17445971 5759274..5759981 1 NC_022657.1 COG1011 Predicted hydrolase (HAD superfamily); putative HAD-hydrolase 5759981 17445971 AFR_26535 Actinoplanes friuliensis DSM 7358 putative HAD-hydrolase YP_008736622.1 5759274 D 1246995 CDS YP_008736623.1 556568198 17445972 5759972..5760484 1 NC_022657.1 pyridoxamine 5'-phosphate oxidase-related protein 5760484 17445972 AFR_26540 Actinoplanes friuliensis DSM 7358 pyridoxamine 5'-phosphate oxidase-related protein YP_008736623.1 5759972 D 1246995 CDS YP_008736624.1 556568199 17445973 complement(5760481..5761086) 1 NC_022657.1 COG1280 Putative threonine efflux protein; putative LysE family protein 5761086 17445973 AFR_26545 Actinoplanes friuliensis DSM 7358 putative LysE family protein YP_008736624.1 5760481 R 1246995 CDS YP_008736625.1 556568200 17445974 5761128..5761685 1 NC_022657.1 COG0283 Cytidylate kinase; hypothetical protein 5761685 17445974 AFR_26550 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736625.1 5761128 D 1246995 CDS YP_008736626.1 556568201 17445975 5761740..5763068 1 NC_022657.1 COG4564 Signal transduction histidine kinase; Hybrid signal transduction histidine kinase K 5763068 17445975 AFR_26555 Actinoplanes friuliensis DSM 7358 Hybrid signal transduction histidine kinase K YP_008736626.1 5761740 D 1246995 CDS YP_008736627.1 556568202 17445976 5763065..5763715 1 NC_022657.1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; LuxR family two component transcriptional regulator 5763715 17445976 AFR_26560 Actinoplanes friuliensis DSM 7358 LuxR family two component transcriptional regulator YP_008736627.1 5763065 D 1246995 CDS YP_008736628.1 556568203 17445977 complement(5763700..5767338) 1 NC_022657.1 COG0646 Methionine synthase I (cobalamin-dependent), methyltransferase domain; B12-dependent methionine synthase 5767338 metH 17445977 metH Actinoplanes friuliensis DSM 7358 B12-dependent methionine synthase YP_008736628.1 5763700 R 1246995 CDS YP_008736629.1 556568204 17445978 5767656..5768525 1 NC_022657.1 hypothetical protein 5768525 17445978 AFR_26570 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736629.1 5767656 D 1246995 CDS YP_008736630.1 556568205 17445979 complement(5768582..5768773) 1 NC_022657.1 hypothetical protein 5768773 17445979 AFR_26575 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736630.1 5768582 R 1246995 CDS YP_008736631.1 556568206 17445980 complement(5769234..5770130) 1 NC_022657.1 putative DNA-binding protein 5770130 17445980 AFR_26580 Actinoplanes friuliensis DSM 7358 putative DNA-binding protein YP_008736631.1 5769234 R 1246995 CDS YP_008736632.1 556568207 17445981 complement(5770350..5770757) 1 NC_022657.1 hypothetical protein 5770757 17445981 AFR_26585 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736632.1 5770350 R 1246995 CDS YP_008736633.1 556568208 17445982 complement(5771033..5772331) 1 NC_022657.1 COG0577 ABC-type antimicrobial peptide transport system, permease component; putative permease 5772331 17445982 AFR_26590 Actinoplanes friuliensis DSM 7358 putative permease YP_008736633.1 5771033 R 1246995 CDS YP_008736634.1 556568209 17445983 complement(5772328..5773068) 1 NC_022657.1 COG1136 ABC-type antimicrobial peptide transport system, ATPase component; putative ABC transporter ATP-binding protein 5773068 17445983 AFR_26595 Actinoplanes friuliensis DSM 7358 putative ABC transporter ATP-binding protein YP_008736634.1 5772328 R 1246995 CDS YP_008736635.1 556568210 17445984 5773180..5774070 1 NC_022657.1 COG2188 Transcriptional regulators; putative TetR-family transcriptional regulator 5774070 17445984 AFR_26600 Actinoplanes friuliensis DSM 7358 putative TetR-family transcriptional regulator YP_008736635.1 5773180 D 1246995 CDS YP_008736636.1 556568211 17445985 complement(5774067..5774420) 1 NC_022657.1 hypothetical protein 5774420 17445985 AFR_26605 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736636.1 5774067 R 1246995 CDS YP_008736637.1 556568212 17445986 complement(5774430..5775242) 1 NC_022657.1 COG0500 SAM-dependent methyltransferases; SAM-dependent methyltransferase 5775242 17445986 AFR_26610 Actinoplanes friuliensis DSM 7358 SAM-dependent methyltransferase YP_008736637.1 5774430 R 1246995 CDS YP_008736638.1 556568213 17445987 5775348..5776139 1 NC_022657.1 COG2188 Transcriptional regulators; GntR family transcriptional regulator 5776139 17445987 AFR_26615 Actinoplanes friuliensis DSM 7358 GntR family transcriptional regulator YP_008736638.1 5775348 D 1246995 CDS YP_008736639.1 556568214 17445988 complement(5776126..5776629) 1 NC_022657.1 COG1846 Transcriptional regulators; MarR family transcriptional regulator 5776629 17445988 AFR_26620 Actinoplanes friuliensis DSM 7358 MarR family transcriptional regulator YP_008736639.1 5776126 R 1246995 CDS YP_008736640.1 556568215 17445989 5776712..5777779 1 NC_022657.1 COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family; putative NADH:flavin oxidoreductase 5777779 17445989 AFR_26625 Actinoplanes friuliensis DSM 7358 putative NADH:flavin oxidoreductase YP_008736640.1 5776712 D 1246995 CDS YP_008736641.1 556568216 17445990 complement(5777799..5779037) 1 NC_022657.1 COG0215 Cysteinyl-tRNA synthetase; cysteine--1-D-myo-inosityl 2-amino-2-deoxy-alpha-D-glucopyranoside ligase 5779037 17445990 AFR_26630 Actinoplanes friuliensis DSM 7358 cysteine--1-D-myo-inosityl 2-amino-2-deoxy-alpha-D-glucopyranoside ligase YP_008736641.1 5777799 R 1246995 CDS YP_008736642.1 556568217 17445991 complement(5779093..5779887) 1 NC_022657.1 hypothetical protein 5779887 17445991 AFR_26635 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736642.1 5779093 R 1246995 CDS YP_008736643.1 556568218 17445992 complement(5779905..5780507) 1 NC_022657.1 hypothetical protein 5780507 17445992 AFR_26640 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736643.1 5779905 R 1246995 CDS YP_008736644.1 556568219 17445993 complement(5780617..5781309) 1 NC_022657.1 COG0406 Fructose-2,6-bisphosphatase; putative phosphoglycerate mutase 5781309 17445993 AFR_26645 Actinoplanes friuliensis DSM 7358 putative phosphoglycerate mutase YP_008736644.1 5780617 R 1246995 CDS YP_008736645.1 556568220 17445994 complement(5781312..5782364) 1 NC_022657.1 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases; Alkanesulfonate monooxygenase 5782364 17445994 AFR_26650 Actinoplanes friuliensis DSM 7358 Alkanesulfonate monooxygenase YP_008736645.1 5781312 R 1246995 CDS YP_008736646.1 556568221 17445995 5782530..5783546 1 NC_022657.1 COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases); Aldo-keto reductase-like family 1 member C1 protein 5783546 17445995 AFR_26655 Actinoplanes friuliensis DSM 7358 Aldo-keto reductase-like family 1 member C1 protein YP_008736646.1 5782530 D 1246995 CDS YP_008736647.1 556568222 17445996 5783552..5783743 1 NC_022657.1 hypothetical protein 5783743 17445996 AFR_26660 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736647.1 5783552 D 1246995 CDS YP_008736648.1 556568223 17445997 complement(5783788..5784246) 1 NC_022657.1 hypothetical protein 5784246 17445997 AFR_26665 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736648.1 5783788 R 1246995 CDS YP_008736649.1 556568224 17445998 complement(5784268..5784876) 1 NC_022657.1 COG2345 Predicted transcriptional regulator; transcriptional regulator 5784876 17445998 AFR_26670 Actinoplanes friuliensis DSM 7358 transcriptional regulator YP_008736649.1 5784268 R 1246995 CDS YP_008736650.1 556568225 17445999 complement(5784957..5785625) 1 NC_022657.1 hypothetical protein 5785625 17445999 AFR_26675 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736650.1 5784957 R 1246995 CDS YP_008736651.1 556568226 17446000 complement(5785645..5786955) 1 NC_022657.1 COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases; hypothetical protein 5786955 17446000 AFR_26680 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736651.1 5785645 R 1246995 CDS YP_008736652.1 556568227 17446001 5787024..5787626 1 NC_022657.1 hypothetical protein 5787626 17446001 AFR_26685 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736652.1 5787024 D 1246995 CDS YP_008736653.1 556568228 17446002 5787805..5788785 1 NC_022657.1 COG0583 Transcriptional regulator; putative RuBisCO transcriptional regulator 5788785 17446002 AFR_26690 Actinoplanes friuliensis DSM 7358 putative RuBisCO transcriptional regulator YP_008736653.1 5787805 D 1246995 CDS YP_008736654.1 556568229 17446003 complement(5788823..5791342) 1 NC_022657.1 COG0542 ATPases with chaperone activity, ATP-binding subunit; putative ATPase associated with various cellular activities 5791342 17446003 AFR_26695 Actinoplanes friuliensis DSM 7358 putative ATPase associated with various cellular activities YP_008736654.1 5788823 R 1246995 CDS YP_008736655.1 556568230 17446004 5791459..5791833 1 NC_022657.1 IgA FC receptor 5791833 17446004 AFR_26700 Actinoplanes friuliensis DSM 7358 IgA FC receptor YP_008736655.1 5791459 D 1246995 CDS YP_008736656.1 556568231 17446005 5791941..5792201 1 NC_022657.1 COG1813 Predicted transcription factor, homolog of eukaryotic MBF1; hypothetical protein 5792201 17446005 AFR_26705 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736656.1 5791941 D 1246995 CDS YP_008736657.1 556568232 17446006 5792206..5795721 1 NC_022657.1 COG1674 DNA segregation ATPase FtsK/SpoIIIE and related proteins; putative FtsK/SpoIIIE family protein 5795721 17446006 AFR_26710 Actinoplanes friuliensis DSM 7358 putative FtsK/SpoIIIE family protein YP_008736657.1 5792206 D 1246995 CDS YP_008736658.1 556568233 17446007 5795718..5796431 1 NC_022657.1 hypothetical protein 5796431 17446007 AFR_26715 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736658.1 5795718 D 1246995 CDS YP_008736659.1 556568234 17446008 complement(5797752..5798999) 1 NC_022657.1 COG2850 Uncharacterized conserved protein; transcription factor jumonji jmjC domain-containing protein 5798999 17446008 AFR_26720 Actinoplanes friuliensis DSM 7358 transcription factor jumonji jmjC domain-containing protein YP_008736659.1 5797752 R 1246995 CDS YP_008736660.1 556568235 17446009 complement(5799010..5799192) 1 NC_022657.1 hypothetical protein 5799192 17446009 AFR_26725 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736660.1 5799010 R 1246995 CDS YP_008736661.1 556568236 17446010 5799286..5800026 1 NC_022657.1 COG1801 Uncharacterized conserved protein; hypothetical protein 5800026 17446010 AFR_26730 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736661.1 5799286 D 1246995 CDS YP_008736662.1 556568237 17446011 5800036..5800824 1 NC_022657.1 COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase; hypothetical protein 5800824 17446011 AFR_26735 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736662.1 5800036 D 1246995 CDS YP_008736663.1 556568238 17446012 complement(5800821..5801693) 1 NC_022657.1 COG1801 Uncharacterized conserved protein; hypothetical protein 5801693 17446012 AFR_26740 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736663.1 5800821 R 1246995 CDS YP_008736664.1 556568239 17446013 complement(5801765..5802184) 1 NC_022657.1 COG1734 DnaK suppressor protein; putative TraR/DksA-family transcriptional regulator 5802184 17446013 AFR_26745 Actinoplanes friuliensis DSM 7358 putative TraR/DksA-family transcriptional regulator YP_008736664.1 5801765 R 1246995 CDS YP_008736665.1 556568240 17446014 complement(5802404..5803027) 1 NC_022657.1 hypothetical protein 5803027 17446014 AFR_26750 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736665.1 5802404 R 1246995 CDS YP_008736666.1 556568241 17446015 complement(5803037..5803621) 1 NC_022657.1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; yclJ-like transcriptional regulatory protein 5803621 17446015 AFR_26755 Actinoplanes friuliensis DSM 7358 yclJ-like transcriptional regulatory protein YP_008736666.1 5803037 R 1246995 CDS YP_008736667.1 556568242 17446016 complement(5803877..5804254) 1 NC_022657.1 hypothetical protein 5804254 17446016 AFR_26760 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736667.1 5803877 R 1246995 CDS YP_008736668.1 556568243 17446017 5804307..5804708 1 NC_022657.1 COG0666 FOG: Ankyrin repeat; Ankyrin-1 5804708 17446017 AFR_26765 Actinoplanes friuliensis DSM 7358 Ankyrin-1 YP_008736668.1 5804307 D 1246995 CDS YP_008736669.1 556568244 17446018 5804705..5805634 1 NC_022657.1 hypothetical protein 5805634 17446018 AFR_26770 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736669.1 5804705 D 1246995 CDS YP_008736670.1 556568245 17446019 complement(5805635..5807923) 1 NC_022657.1 COG0653 Preprotein translocase subunit SecA (ATPase, RNA helicase); preprotein translocase subunit SecA 5807923 17446019 AFR_26775 Actinoplanes friuliensis DSM 7358 preprotein translocase subunit SecA YP_008736670.1 5805635 R 1246995 CDS YP_008736671.1 556568246 17446020 complement(5807996..5809741) 1 NC_022657.1 COG1132 ABC-type multidrug transport system, ATPase and permease components; ABC transporter 5809741 17446020 AFR_26780 Actinoplanes friuliensis DSM 7358 ABC transporter YP_008736671.1 5807996 R 1246995 CDS YP_008736672.1 556568247 17446021 5809875..5810612 1 NC_022657.1 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); putative PAS/PAC sensor protein 5810612 17446021 AFR_26785 Actinoplanes friuliensis DSM 7358 putative PAS/PAC sensor protein YP_008736672.1 5809875 D 1246995 CDS YP_008736673.1 556568248 17446022 5810716..5811744 1 NC_022657.1 COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain; two-component system, chemotaxis family, response regulator CheB 5811744 17446022 AFR_26790 Actinoplanes friuliensis DSM 7358 two-component system, chemotaxis family, response regulator CheB YP_008736673.1 5810716 D 1246995 CDS YP_008736674.1 556568249 17446023 5811778..5813625 1 NC_022657.1 COG1352 Methylase of chemotaxis methyl-accepting proteins; putative MCP methyltransferase CheR with PAS domain 5813625 17446023 AFR_26795 Actinoplanes friuliensis DSM 7358 putative MCP methyltransferase CheR with PAS domain YP_008736674.1 5811778 D 1246995 CDS YP_008736675.1 556568250 17446024 5813688..5814428 1 NC_022657.1 hypothetical protein 5814428 17446024 AFR_26800 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736675.1 5813688 D 1246995 CDS YP_008736676.1 556568251 17446025 complement(5814425..5815504) 1 NC_022657.1 COG1191 DNA-directed RNA polymerase specialized sigma subunit; putative RNA polymerase sigma factor with STAS domain 5815504 17446025 AFR_26805 Actinoplanes friuliensis DSM 7358 putative RNA polymerase sigma factor with STAS domain YP_008736676.1 5814425 R 1246995 CDS YP_008736677.1 556568252 17446026 complement(5815743..5817341) 1 NC_022657.1 collagen like protein 5817341 17446026 AFR_26810 Actinoplanes friuliensis DSM 7358 collagen like protein YP_008736677.1 5815743 R 1246995 CDS YP_008736678.1 556568253 17446027 5819010..5819291 1 NC_022657.1 COG3369 Uncharacterized conserved protein; hypothetical protein 5819291 17446027 AFR_26820 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736678.1 5819010 D 1246995 CDS YP_008736679.1 556568254 17446028 complement(5819237..5820202) 1 NC_022657.1 hypothetical protein 5820202 17446028 AFR_26825 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736679.1 5819237 R 1246995 CDS YP_008736680.1 556568255 17446029 5820384..5820923 1 NC_022657.1 hypothetical protein 5820923 17446029 AFR_26830 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736680.1 5820384 D 1246995 CDS YP_008736681.1 556568256 17446030 complement(5820928..5822202) 1 NC_022657.1 COG2755 Lysophospholipase L1 and related esterases; SGNH hydrolase 5822202 17446030 AFR_26835 Actinoplanes friuliensis DSM 7358 SGNH hydrolase YP_008736681.1 5820928 R 1246995 CDS YP_008736682.1 556568257 17446031 5822285..5823133 1 NC_022657.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); alpha/beta hydrolase fold protein 5823133 17446031 AFR_26840 Actinoplanes friuliensis DSM 7358 alpha/beta hydrolase fold protein YP_008736682.1 5822285 D 1246995 CDS YP_008736683.1 556568258 17446032 complement(5823096..5823422) 1 NC_022657.1 DnaJ domain-containing protein 5823422 17446032 AFR_26845 Actinoplanes friuliensis DSM 7358 DnaJ domain-containing protein YP_008736683.1 5823096 R 1246995 CDS YP_008736684.1 556568259 17446033 5823514..5824989 1 NC_022657.1 hypothetical protein 5824989 17446033 AFR_26850 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736684.1 5823514 D 1246995 CDS YP_008736685.1 556568260 17446034 5824974..5825561 1 NC_022657.1 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins; yoaA-like N-acetyltransferase 5825561 17446034 AFR_26855 Actinoplanes friuliensis DSM 7358 yoaA-like N-acetyltransferase YP_008736685.1 5824974 D 1246995 CDS YP_008736686.1 556568261 17446035 5825630..5825998 1 NC_022657.1 hypothetical protein 5825998 17446035 AFR_26860 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736686.1 5825630 D 1246995 CDS YP_008736687.1 556568262 17446036 5825995..5826624 1 NC_022657.1 hypothetical protein 5826624 17446036 AFR_26865 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736687.1 5825995 D 1246995 CDS YP_008736688.1 556568263 17446037 5826621..5826989 1 NC_022657.1 COG3467 Predicted flavin-nucleotide-binding protein; pyridoxamine 5'-phosphate oxidase-related protein 5826989 17446037 AFR_26870 Actinoplanes friuliensis DSM 7358 pyridoxamine 5'-phosphate oxidase-related protein YP_008736688.1 5826621 D 1246995 CDS YP_008736689.1 556568264 17446038 complement(5826986..5827684) 1 NC_022657.1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; response regulator receiver protein 5827684 17446038 AFR_26875 Actinoplanes friuliensis DSM 7358 response regulator receiver protein YP_008736689.1 5826986 R 1246995 CDS YP_008736690.1 556568265 17446039 complement(5827677..5829725) 1 NC_022657.1 COG4585 Signal transduction histidine kinase; signal transduction histidine kinase-like protein 5829725 17446039 AFR_26880 Actinoplanes friuliensis DSM 7358 signal transduction histidine kinase-like protein YP_008736690.1 5827677 R 1246995 CDS YP_008736691.1 556568266 17446040 5829837..5830133 1 NC_022657.1 COG1396 Predicted transcriptional regulators; helix-turn-helix domain-containing protein 5830133 17446040 AFR_26885 Actinoplanes friuliensis DSM 7358 helix-turn-helix domain-containing protein YP_008736691.1 5829837 D 1246995 CDS YP_008736692.1 556568267 17446041 5830130..5830681 1 NC_022657.1 COG1335 Amidases related to nicotinamidase; isochorismatase hydrolase 5830681 17446041 AFR_26890 Actinoplanes friuliensis DSM 7358 isochorismatase hydrolase YP_008736692.1 5830130 D 1246995 CDS YP_008736693.1 556568268 17446042 complement(5830668..5831057) 1 NC_022657.1 hypothetical protein 5831057 17446042 AFR_26895 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736693.1 5830668 R 1246995 CDS YP_008736694.1 556568269 17446043 complement(5831064..5831909) 1 NC_022657.1 COG0500 SAM-dependent methyltransferases; S-adenosyl-L-methionine (SAM)-dependent methyltransferase 5831909 17446043 AFR_26900 Actinoplanes friuliensis DSM 7358 S-adenosyl-L-methionine (SAM)-dependent methyltransferase YP_008736694.1 5831064 R 1246995 CDS YP_008736695.1 556568270 17446044 complement(5831911..5832207) 1 NC_022657.1 hypothetical protein 5832207 17446044 AFR_26905 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736695.1 5831911 R 1246995 CDS YP_008736696.1 556568271 17446045 5832264..5832905 1 NC_022657.1 COG1309 Transcriptional regulator; HTH-type transcriptional regulator mtrR 5832905 17446045 AFR_26910 Actinoplanes friuliensis DSM 7358 HTH-type transcriptional regulator mtrR YP_008736696.1 5832264 D 1246995 CDS YP_008736697.1 556568272 17446046 complement(5832895..5834253) 1 NC_022657.1 COG1797 Cobyrinic acid a,c-diamide synthase; cobyrinic acid a,c-diamide synthase 5834253 17446046 AFR_26915 Actinoplanes friuliensis DSM 7358 cobyrinic acid a,c-diamide synthase YP_008736697.1 5832895 R 1246995 CDS YP_008736698.1 556568273 17446047 complement(5834247..5834846) 1 NC_022657.1 COG2109 ATP:corrinoid adenosyltransferase; cob(I)alamin adenolsyltransferase/cobinamide ATP-dependent adenolsyltransferase 5834846 17446047 AFR_26920 Actinoplanes friuliensis DSM 7358 cob(I)alamin adenolsyltransferase/cobinamide ATP-dependent adenolsyltransferase YP_008736698.1 5834247 R 1246995 CDS YP_008736699.1 556568274 17446048 complement(5834890..5836659) 1 NC_022657.1 COG1239 Mg-chelatase subunit ChlI; magnesium chelatase subunit ChlD 5836659 17446048 AFR_26925 Actinoplanes friuliensis DSM 7358 magnesium chelatase subunit ChlD YP_008736699.1 5834890 R 1246995 CDS YP_008736700.1 556568275 17446049 complement(5837557..5839128) 1 NC_022657.1 COG1070 Sugar (pentulose and hexulose) kinases; putative FGGY-family carbohydrate kinase 5839128 17446049 AFR_26930 Actinoplanes friuliensis DSM 7358 putative FGGY-family carbohydrate kinase YP_008736700.1 5837557 R 1246995 CDS YP_008736701.1 556568276 17446050 complement(5839178..5840488) 1 NC_022657.1 hypothetical protein 5840488 17446050 AFR_26935 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736701.1 5839178 R 1246995 CDS YP_008736702.1 556568277 17446051 complement(5840485..5840982) 1 NC_022657.1 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; ECF subfamily RNA polymerase sigma-24 factor 5840982 17446051 AFR_26940 Actinoplanes friuliensis DSM 7358 ECF subfamily RNA polymerase sigma-24 factor YP_008736702.1 5840485 R 1246995 CDS YP_008736703.1 556568278 17446052 complement(5841039..5841560) 1 NC_022657.1 COG3832 Uncharacterized conserved protein; hypothetical protein 5841560 17446052 AFR_26945 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736703.1 5841039 R 1246995 CDS YP_008736704.1 556568279 17446053 complement(5841557..5841862) 1 NC_022657.1 COG0640 Predicted transcriptional regulators; ArsR family transcriptional regulator 5841862 17446053 AFR_26950 Actinoplanes friuliensis DSM 7358 ArsR family transcriptional regulator YP_008736704.1 5841557 R 1246995 CDS YP_008736705.1 556568280 17446054 5841921..5843171 1 NC_022657.1 COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase; glycosyl transferase family protein 5843171 17446054 AFR_26955 Actinoplanes friuliensis DSM 7358 glycosyl transferase family protein YP_008736705.1 5841921 D 1246995 CDS YP_008736706.1 556568281 17446055 complement(5843203..5844486) 1 NC_022657.1 COG0372 Citrate synthase; citrate synthase 5844486 17446055 AFR_26960 Actinoplanes friuliensis DSM 7358 citrate synthase YP_008736706.1 5843203 R 1246995 CDS YP_008736707.1 556568282 17446056 5844667..5845524 1 NC_022657.1 hypothetical protein 5845524 17446056 AFR_26965 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736707.1 5844667 D 1246995 CDS YP_008736708.1 556568283 17446057 5845542..5847839 1 NC_022657.1 COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain; putative signaling protein 5847839 17446057 AFR_26970 Actinoplanes friuliensis DSM 7358 putative signaling protein YP_008736708.1 5845542 D 1246995 CDS YP_008736709.1 556568284 17446058 5848137..5848940 1 NC_022657.1 COG0708 Exonuclease III; exodeoxyribonuclease III 5848940 17446058 AFR_26975 Actinoplanes friuliensis DSM 7358 exodeoxyribonuclease III YP_008736709.1 5848137 D 1246995 CDS YP_008736710.1 556568285 17446059 5848995..5850656 1 NC_022657.1 COG2208 Serine phosphatase RsbU, regulator of sigma subunit; putative magnesium/manganese-dependent protein phosphatase 5850656 17446059 AFR_26980 Actinoplanes friuliensis DSM 7358 putative magnesium/manganese-dependent protein phosphatase YP_008736710.1 5848995 D 1246995 CDS YP_008736711.1 556568286 17446060 5850653..5851696 1 NC_022657.1 COG5012 Predicted cobalamin binding protein; hypothetical protein 5851696 17446060 AFR_26985 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736711.1 5850653 D 1246995 CDS YP_008736712.1 556568287 17446061 5851853..5852086 1 NC_022657.1 hypothetical protein 5852086 17446061 AFR_26990 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736712.1 5851853 D 1246995 CDS YP_008736713.1 556568288 17446062 complement(5852159..5852677) 1 NC_022657.1 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins; hypothetical protein 5852677 17446062 AFR_26995 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736713.1 5852159 R 1246995 CDS YP_008736714.1 556568289 17446063 complement(5852757..5853488) 1 NC_022657.1 hypothetical protein 5853488 17446063 AFR_27000 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736714.1 5852757 R 1246995 CDS YP_008736715.1 556568290 17446064 complement(5853556..5853936) 1 NC_022657.1 hypothetical protein 5853936 17446064 AFR_27005 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736715.1 5853556 R 1246995 CDS YP_008736716.1 556568291 17446065 complement(5854052..5856361) 1 NC_022657.1 COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain; Protein gmr 5856361 17446065 AFR_27010 Actinoplanes friuliensis DSM 7358 Protein gmr YP_008736716.1 5854052 R 1246995 CDS YP_008736717.1 556568292 17446066 complement(5856417..5860340) 1 NC_022657.1 COG1643 HrpA-like helicases; putative ATP-dependent helicase 5860340 17446066 AFR_27015 Actinoplanes friuliensis DSM 7358 putative ATP-dependent helicase YP_008736717.1 5856417 R 1246995 CDS YP_008736718.1 556568293 17446067 complement(5860384..5861181) 1 NC_022657.1 COG0656 Aldo/keto reductases, related to diketogulonate reductase; aldo/keto reductase 5861181 17446067 AFR_27020 Actinoplanes friuliensis DSM 7358 aldo/keto reductase YP_008736718.1 5860384 R 1246995 CDS YP_008736719.1 556568294 17446068 5861322..5861687 1 NC_022657.1 COG0784 FOG: CheY-like receiver; putative response regulator receiver domain protein 5861687 17446068 AFR_27025 Actinoplanes friuliensis DSM 7358 putative response regulator receiver domain protein YP_008736719.1 5861322 D 1246995 CDS YP_008736720.1 556568295 17446069 complement(5861620..5863860) 1 NC_022657.1 COG5002 Signal transduction histidine kinase; putative PAS-sensor signal transduction histidine kinase 5863860 17446069 AFR_27030 Actinoplanes friuliensis DSM 7358 putative PAS-sensor signal transduction histidine kinase YP_008736720.1 5861620 R 1246995 CDS YP_008736721.1 556568296 17446070 complement(5864010..5865170) 1 NC_022657.1 COG1705 Muramidase (flagellum-specific); lysozyme 5865170 17446070 AFR_27035 Actinoplanes friuliensis DSM 7358 lysozyme YP_008736721.1 5864010 R 1246995 CDS YP_008736722.1 556568297 17446071 5865383..5866333 1 NC_022657.1 COG0671 Membrane-associated phospholipid phosphatase; phosphoesterase, PA-phosphatase-like protein 5866333 17446071 AFR_27040 Actinoplanes friuliensis DSM 7358 phosphoesterase, PA-phosphatase-like protein YP_008736722.1 5865383 D 1246995 CDS YP_008736723.1 556568298 17446072 5866349..5866918 1 NC_022657.1 hypothetical protein 5866918 17446072 AFR_27045 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736723.1 5866349 D 1246995 CDS YP_008736724.1 556568299 17446073 complement(5866989..5867750) 1 NC_022657.1 COG1191 DNA-directed RNA polymerase specialized sigma subunit; RNA polymerase sigma factor rpoD 5867750 17446073 AFR_27050 Actinoplanes friuliensis DSM 7358 RNA polymerase sigma factor rpoD YP_008736724.1 5866989 R 1246995 CDS YP_008736725.1 556568300 17446074 complement(5867885..5870545) 1 NC_022657.1 COG2199 FOG: GGDEF domain; signal transduction protein containing a membrane domain an EAL and a GGDEF domain 5870545 17446074 AFR_27055 Actinoplanes friuliensis DSM 7358 signal transduction protein containing a membrane domain an EAL and a GGDEF domain YP_008736725.1 5867885 R 1246995 CDS YP_008736726.1 556568301 17446075 complement(5870371..5871975) 1 NC_022657.1 COG1404 Subtilisin-like serine proteases; peptidase S8 and S53 subtilisin kexin sedolisin 5871975 17446075 AFR_27060 Actinoplanes friuliensis DSM 7358 peptidase S8 and S53 subtilisin kexin sedolisin YP_008736726.1 5870371 R 1246995 CDS YP_008736727.1 556568302 17446076 5872194..5872973 1 NC_022657.1 COG1940 Transcriptional regulator/sugar kinase; polyphosphate glucokinase 5872973 17446076 AFR_27065 Actinoplanes friuliensis DSM 7358 polyphosphate glucokinase YP_008736727.1 5872194 D 1246995 CDS YP_008736728.1 556568303 17446077 5873007..5873468 1 NC_022657.1 putative pyridoxamine 5'-phosphate oxidase-related protein 5873468 17446077 AFR_27070 Actinoplanes friuliensis DSM 7358 putative pyridoxamine 5'-phosphate oxidase-related protein YP_008736728.1 5873007 D 1246995 CDS YP_008736729.1 556568304 17446078 complement(5873541..5874461) 1 NC_022657.1 hypothetical protein 5874461 17446078 AFR_27075 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736729.1 5873541 R 1246995 CDS YP_008736730.1 556568305 17446079 complement(5874451..5874954) 1 NC_022657.1 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; ECF subfamily RNA polymerase sigma-24 subunit 5874954 17446079 AFR_27080 Actinoplanes friuliensis DSM 7358 ECF subfamily RNA polymerase sigma-24 subunit YP_008736730.1 5874451 R 1246995 CDS YP_008736731.1 556568306 17446080 complement(5875107..5875673) 1 NC_022657.1 hypothetical protein 5875673 17446080 AFR_27085 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736731.1 5875107 R 1246995 CDS YP_008736732.1 556568307 17446081 5875767..5876582 1 NC_022657.1 COG0421 Spermidine synthase; hypothetical protein 5876582 17446081 AFR_27090 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736732.1 5875767 D 1246995 CDS YP_008736733.1 556568308 17446082 5876761..5878692 1 NC_022657.1 COG0366 Glycosidases; putative glycosyl hydrolase 5878692 17446082 AFR_27095 Actinoplanes friuliensis DSM 7358 putative glycosyl hydrolase YP_008736733.1 5876761 D 1246995 CDS YP_008736734.1 556568309 17446083 5878741..5880516 1 NC_022657.1 COG0366 Glycosidases; trehalose synthase 5880516 17446083 AFR_27100 Actinoplanes friuliensis DSM 7358 trehalose synthase YP_008736734.1 5878741 D 1246995 CDS YP_008736735.1 556568310 17446084 5880513..5881823 1 NC_022657.1 COG3281 Uncharacterized protein, probably involved in trehalose biosynthesis; putative maltokinase 5881823 17446084 AFR_27105 Actinoplanes friuliensis DSM 7358 putative maltokinase YP_008736735.1 5880513 D 1246995 CDS YP_008736736.1 556568311 17446085 5881847..5884009 1 NC_022657.1 COG0296 1,4-alpha-glucan branching enzyme; glycogen branching enzyme 5884009 17446085 AFR_27110 Actinoplanes friuliensis DSM 7358 glycogen branching enzyme YP_008736736.1 5881847 D 1246995 CDS YP_008736737.1 556568312 17446086 5884073..5884465 1 NC_022657.1 COG0456 Acetyltransferases; Acetyltransferase 5884465 17446086 AFR_27115 Actinoplanes friuliensis DSM 7358 Acetyltransferase YP_008736737.1 5884073 D 1246995 CDS YP_008736738.1 556568313 17446087 5884509..5885237 1 NC_022657.1 hypothetical protein 5885237 17446087 AFR_27120 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736738.1 5884509 D 1246995 CDS YP_008736739.1 556568314 17446088 5885681..5886097 1 NC_022657.1 COG2764 Uncharacterized protein conserved in bacteria; hypothetical protein 5886097 17446088 AFR_27125 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736739.1 5885681 D 1246995 CDS YP_008736740.1 556568315 17446089 5886097..5886450 1 NC_022657.1 hypothetical protein 5886450 17446089 AFR_27130 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736740.1 5886097 D 1246995 CDS YP_008736741.1 556568316 17446090 complement(5886402..5886950) 1 NC_022657.1 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins; N-acetyltransferase GCN5 5886950 17446090 AFR_27135 Actinoplanes friuliensis DSM 7358 N-acetyltransferase GCN5 YP_008736741.1 5886402 R 1246995 CDS YP_008736742.1 556568317 17446091 5887009..5887347 1 NC_022657.1 hypothetical protein 5887347 17446091 AFR_27140 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736742.1 5887009 D 1246995 CDS YP_008736743.1 556568318 17446092 complement(5887475..5888176) 1 NC_022657.1 COG0631 Serine/threonine protein phosphatase; protein phosphatase 5888176 17446092 AFR_27145 Actinoplanes friuliensis DSM 7358 protein phosphatase YP_008736743.1 5887475 R 1246995 CDS YP_008736744.1 556568319 17446093 5888262..5889242 1 NC_022657.1 COG3899 Predicted ATPase; LuxR family transcriptional regulator 5889242 17446093 AFR_27150 Actinoplanes friuliensis DSM 7358 LuxR family transcriptional regulator YP_008736744.1 5888262 D 1246995 CDS YP_008736745.1 556568320 17446094 complement(5889220..5890257) 1 NC_022657.1 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases; theronine dehydrogenase-like Zn-dependent dehydrogenase 5890257 17446094 AFR_27155 Actinoplanes friuliensis DSM 7358 theronine dehydrogenase-like Zn-dependent dehydrogenase YP_008736745.1 5889220 R 1246995 CDS YP_008736746.1 556568321 17446095 5890337..5892883 1 NC_022657.1 COG2183 Transcriptional accessory protein; transcriptional accessory protein 5892883 17446095 AFR_27160 Actinoplanes friuliensis DSM 7358 transcriptional accessory protein YP_008736746.1 5890337 D 1246995 CDS YP_008736747.1 556568322 17446096 complement(5893146..5894909) 1 NC_022657.1 COG0515 Serine/threonine protein kinase; putative serine/threonine protein kinase 5894909 17446096 AFR_27165 Actinoplanes friuliensis DSM 7358 putative serine/threonine protein kinase YP_008736747.1 5893146 R 1246995 CDS YP_008736748.1 556568323 17446097 5895110..5896066 1 NC_022657.1 COG0583 Transcriptional regulator; LysR family transcriptional regulator 5896066 17446097 AFR_27170 Actinoplanes friuliensis DSM 7358 LysR family transcriptional regulator YP_008736748.1 5895110 D 1246995 CDS YP_008736749.1 556568324 17446098 complement(5896079..5897266) 1 NC_022657.1 COG3552 Protein containing von Willebrand factor type A (vWA) domain; VWA containing CoxE family protein 5897266 17446098 AFR_27175 Actinoplanes friuliensis DSM 7358 VWA containing CoxE family protein YP_008736749.1 5896079 R 1246995 CDS YP_008736750.1 556568325 17446099 complement(5897253..5898482) 1 NC_022657.1 COG3427 Uncharacterized conserved protein; carbon monoxide dehydrogenase subunit g 5898482 17446099 AFR_27180 Actinoplanes friuliensis DSM 7358 carbon monoxide dehydrogenase subunit g YP_008736750.1 5897253 R 1246995 CDS YP_008736751.1 556568326 17446100 complement(5898479..5899378) 1 NC_022657.1 COG0714 MoxR-like ATPases; putative MoxR-like ATPase 5899378 17446100 AFR_27185 Actinoplanes friuliensis DSM 7358 putative MoxR-like ATPase YP_008736751.1 5898479 R 1246995 CDS YP_008736752.1 556568327 17446101 complement(5899368..5899958) 1 NC_022657.1 COG2068 Uncharacterized MobA-related protein; hypothetical protein 5899958 17446101 AFR_27190 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736752.1 5899368 R 1246995 CDS YP_008736753.1 556568328 17446102 complement(5899962..5900813) 1 NC_022657.1 COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family; hypothetical protein 5900813 17446102 AFR_27195 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736753.1 5899962 R 1246995 CDS YP_008736754.1 556568329 17446103 complement(5900824..5903220) 1 NC_022657.1 COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs; carbon-monoxide dehydrogenase, large subunit 5903220 17446103 AFR_27200 Actinoplanes friuliensis DSM 7358 carbon-monoxide dehydrogenase, large subunit YP_008736754.1 5900824 R 1246995 CDS YP_008736755.1 556568330 17446104 complement(5903217..5903741) 1 NC_022657.1 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs; (2fe-2S)-binding domain-containing protein 5903741 17446104 AFR_27205 Actinoplanes friuliensis DSM 7358 (2fe-2S)-binding domain-containing protein YP_008736755.1 5903217 R 1246995 CDS YP_008736756.1 556568331 17446105 complement(5903744..5904622) 1 NC_022657.1 COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs; putative carbon monoxide dehydrogenase medium chain 5904622 17446105 AFR_27210 Actinoplanes friuliensis DSM 7358 putative carbon monoxide dehydrogenase medium chain YP_008736756.1 5903744 R 1246995 CDS YP_008736757.1 556568332 17446106 complement(5904678..5905361) 1 NC_022657.1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; two-component system response regulator 5905361 17446106 AFR_27215 Actinoplanes friuliensis DSM 7358 two-component system response regulator YP_008736757.1 5904678 R 1246995 CDS YP_008736758.1 556568333 17446107 complement(5905375..5906433) 1 NC_022657.1 COG4585 Signal transduction histidine kinase; histidine kinase 5906433 17446107 AFR_27220 Actinoplanes friuliensis DSM 7358 histidine kinase YP_008736758.1 5905375 R 1246995 CDS YP_008736759.1 556568334 17446108 5906554..5906940 1 NC_022657.1 hypothetical protein 5906940 17446108 AFR_27225 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736759.1 5906554 D 1246995 CDS YP_008736760.1 556568335 17446109 complement(5906906..5908663) 1 NC_022657.1 COG0515 Serine/threonine protein kinase; putative serine/threonine protein kinase 5908663 17446109 AFR_27230 Actinoplanes friuliensis DSM 7358 putative serine/threonine protein kinase YP_008736760.1 5906906 R 1246995 CDS YP_008736761.1 556568336 17446110 complement(5908666..5909526) 1 NC_022657.1 cytochrome c biogenesis protein transmembrane region 5909526 17446110 AFR_27235 Actinoplanes friuliensis DSM 7358 cytochrome c biogenesis protein transmembrane region YP_008736761.1 5908666 R 1246995 CDS YP_008736762.1 556568337 17446111 complement(5909530..5910099) 1 NC_022657.1 COG0526 Thiol-disulfide isomerase and thioredoxins; Thiol-disulfide oxidoreductase resA 5910099 17446111 AFR_27240 Actinoplanes friuliensis DSM 7358 Thiol-disulfide oxidoreductase resA YP_008736762.1 5909530 R 1246995 CDS YP_008736763.1 556568338 17446112 complement(5910096..5911568) 1 NC_022657.1 COG1894 NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit; putative oxidoreductase 5911568 17446112 AFR_27245 Actinoplanes friuliensis DSM 7358 putative oxidoreductase YP_008736763.1 5910096 R 1246995 CDS YP_008736764.1 556568339 17446113 complement(5911565..5913445) 1 NC_022657.1 Eukaryotic translation initiation factor 3 subunit A 5913445 17446113 AFR_27250 Actinoplanes friuliensis DSM 7358 Eukaryotic translation initiation factor 3 subunit A YP_008736764.1 5911565 R 1246995 CDS YP_008736765.1 556568340 17446114 5913901..5914704 1 NC_022657.1 hypothetical protein 5914704 17446114 AFR_27255 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736765.1 5913901 D 1246995 CDS YP_008736766.1 556568341 17446115 5914742..5915278 1 NC_022657.1 COG3544 Uncharacterized protein conserved in bacteria; hypothetical protein 5915278 17446115 AFR_27260 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736766.1 5914742 D 1246995 CDS YP_008736767.1 556568342 17446116 5915402..5915989 1 NC_022657.1 hypothetical protein 5915989 17446116 AFR_27265 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736767.1 5915402 D 1246995 CDS YP_008736768.1 556568343 17446117 complement(5916066..5916155) 1 NC_022657.1 hypothetical protein 5916155 17446117 AFR_27270 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736768.1 5916066 R 1246995 CDS YP_008736769.1 556568344 17446118 complement(5916197..5916673) 1 NC_022657.1 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins; putative GCN5-related N-acetyltransferase 5916673 17446118 AFR_27275 Actinoplanes friuliensis DSM 7358 putative GCN5-related N-acetyltransferase YP_008736769.1 5916197 R 1246995 CDS YP_008736770.1 556568345 17446119 complement(5916666..5917391) 1 NC_022657.1 COG0631 Serine/threonine protein phosphatase; protein phosphatase 2C-like protein 5917391 17446119 AFR_27280 Actinoplanes friuliensis DSM 7358 protein phosphatase 2C-like protein YP_008736770.1 5916666 R 1246995 CDS YP_008736771.1 556568346 17446120 complement(5917445..5919127) 1 NC_022657.1 COG5184 Alpha-tubulin suppressor and related RCC1 domain-containing proteins; chromosome condensation regulator RCC1 5919127 17446120 AFR_27285 Actinoplanes friuliensis DSM 7358 chromosome condensation regulator RCC1 YP_008736771.1 5917445 R 1246995 CDS YP_008736772.1 556568347 17446121 complement(5919203..5919862) 1 NC_022657.1 hypothetical protein 5919862 17446121 AFR_27290 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736772.1 5919203 R 1246995 CDS YP_008736773.1 556568348 17446122 complement(5919941..5920789) 1 NC_022657.1 COG2226 Methylase involved in ubiquinone/menaquinone biosynthesis; chemotaxis protein CheR 5920789 17446122 AFR_27295 Actinoplanes friuliensis DSM 7358 chemotaxis protein CheR YP_008736773.1 5919941 R 1246995 CDS YP_008736774.1 556568349 17446123 complement(5920864..5922609) 1 NC_022657.1 COG5297 Cellobiohydrolase A (1,4-beta-cellobiosidase A); putative glycosyl hydrolase 5922609 17446123 AFR_27300 Actinoplanes friuliensis DSM 7358 putative glycosyl hydrolase YP_008736774.1 5920864 R 1246995 CDS YP_008736775.1 556568350 17446124 complement(5924424..5924519) 1 NC_022657.1 hypothetical protein 5924519 17446124 AFR_27305 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736775.1 5924424 R 1246995 CDS YP_008736776.1 556568351 17446125 complement(5924516..5925904) 1 NC_022657.1 COG0477 Permeases of the major facilitator superfamily; putative MFS transporter 5925904 17446125 AFR_27310 Actinoplanes friuliensis DSM 7358 putative MFS transporter YP_008736776.1 5924516 R 1246995 CDS YP_008736777.1 556568352 17446126 complement(5926718..5927698) 1 NC_022657.1 COG1893 Ketopantoate reductase; ketopantoate reductase ApbA/PanE 5927698 17446126 AFR_27315 Actinoplanes friuliensis DSM 7358 ketopantoate reductase ApbA/PanE YP_008736777.1 5926718 R 1246995 CDS YP_008736778.1 556568353 17446127 5927781..5928347 1 NC_022657.1 COG1309 Transcriptional regulator; TetR family transcriptional regulator 5928347 17446127 AFR_27320 Actinoplanes friuliensis DSM 7358 TetR family transcriptional regulator YP_008736778.1 5927781 D 1246995 CDS YP_008736779.1 556568354 17446128 complement(5928361..5929341) 1 NC_022657.1 COG2374 Predicted extracellular nuclease; hypothetical protein 5929341 17446128 AFR_27325 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736779.1 5928361 R 1246995 CDS YP_008736780.1 556568355 17446129 complement(5929441..5931909) 1 NC_022657.1 COG3250 Beta-galactosidase/beta-glucuronidase; putative hydrolase 5931909 17446129 AFR_27330 Actinoplanes friuliensis DSM 7358 putative hydrolase YP_008736780.1 5929441 R 1246995 CDS YP_008736781.1 556568356 17446130 5932166..5932852 1 NC_022657.1 COG3142 Uncharacterized protein involved in copper resistance; Homeostasis protein 5932852 17446130 AFR_27335 Actinoplanes friuliensis DSM 7358 Homeostasis protein YP_008736781.1 5932166 D 1246995 CDS YP_008736782.1 556568357 17446131 complement(5933290..5934180) 1 NC_022657.1 COG3173 Predicted aminoglycoside phosphotransferase; aminoglycoside phosphotransferase 5934180 17446131 AFR_27340 Actinoplanes friuliensis DSM 7358 aminoglycoside phosphotransferase YP_008736782.1 5933290 R 1246995 CDS YP_008736783.1 556568358 17446132 complement(5934189..5935556) 1 NC_022657.1 COG1004 Predicted UDP-glucose 6-dehydrogenase; putative UDP-glucose 6-dehydrogenase 5935556 17446132 AFR_27345 Actinoplanes friuliensis DSM 7358 putative UDP-glucose 6-dehydrogenase YP_008736783.1 5934189 R 1246995 CDS YP_008736784.1 556568359 17446133 5935615..5937207 1 NC_022657.1 COG2199 FOG: GGDEF domain; putative membrane protein in llm 5'region 5937207 17446133 AFR_27350 Actinoplanes friuliensis DSM 7358 putative membrane protein in llm 5'region YP_008736784.1 5935615 D 1246995 CDS YP_008736785.1 556568360 17446134 5938078..5939091 1 NC_022657.1 COG1609 Transcriptional regulators; LacI family transcriptional regulator 5939091 17446134 AFR_27355 Actinoplanes friuliensis DSM 7358 LacI family transcriptional regulator YP_008736785.1 5938078 D 1246995 CDS YP_008736786.1 556568361 17446135 5939172..5940383 1 NC_022657.1 COG1653 ABC-type sugar transport system, periplasmic component; putative sugar ABC transporter substrate binding protein 5940383 17446135 AFR_27360 Actinoplanes friuliensis DSM 7358 putative sugar ABC transporter substrate binding protein YP_008736786.1 5939172 D 1246995 CDS YP_008736787.1 556568362 17446136 5940376..5941317 1 NC_022657.1 COG1175 ABC-type sugar transport systems, permease components; binding-protein-dependent transport system inner membrane protein 5941317 17446136 AFR_27365 Actinoplanes friuliensis DSM 7358 binding-protein-dependent transport system inner membrane protein YP_008736787.1 5940376 D 1246995 CDS YP_008736788.1 556568363 17446137 5941314..5942120 1 NC_022657.1 COG0395 ABC-type sugar transport system, permease component; transport protein 5942120 17446137 AFR_27370 Actinoplanes friuliensis DSM 7358 transport protein YP_008736788.1 5941314 D 1246995 CDS YP_008736789.1 556568364 17446138 5942131..5942895 1 NC_022657.1 COG4813 Trehalose utilization protein; hypothetical protein 5942895 17446138 AFR_27375 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736789.1 5942131 D 1246995 CDS YP_008736790.1 556568365 17446139 5942892..5943935 1 NC_022657.1 COG0673 Predicted dehydrogenases and related proteins; oxidoreductase domain-containing protein 5943935 17446139 AFR_27380 Actinoplanes friuliensis DSM 7358 oxidoreductase domain-containing protein YP_008736790.1 5942892 D 1246995 CDS YP_008736791.1 556568366 17446140 complement(5944517..5946655) 1 NC_022657.1 COG1289 Predicted membrane protein; hypothetical protein 5946655 17446140 AFR_27385 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736791.1 5944517 R 1246995 CDS YP_008736792.1 556568367 17446141 5946771..5947331 1 NC_022657.1 hypothetical protein 5947331 17446141 AFR_27390 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736792.1 5946771 D 1246995 CDS YP_008736793.1 556568368 17446142 complement(5947368..5948012) 1 NC_022657.1 COG0500 SAM-dependent methyltransferases; methyltransferase 5948012 17446142 AFR_27395 Actinoplanes friuliensis DSM 7358 methyltransferase YP_008736793.1 5947368 R 1246995 CDS YP_008736794.1 556568369 17446143 5948096..5949151 1 NC_022657.1 COG1680 Beta-lactamase class C and other penicillin binding proteins; putative esterase 5949151 17446143 AFR_27400 Actinoplanes friuliensis DSM 7358 putative esterase YP_008736794.1 5948096 D 1246995 CDS YP_008736795.1 556568370 17446144 complement(5949160..5950311) 1 NC_022657.1 COG1960 Acyl-CoA dehydrogenases; putative glutaryl-CoA dehydrogenase 5950311 17446144 AFR_27405 Actinoplanes friuliensis DSM 7358 putative glutaryl-CoA dehydrogenase YP_008736795.1 5949160 R 1246995 CDS YP_008736796.1 556568371 17446145 5950356..5953292 1 NC_022657.1 COG0752 Glycyl-tRNA synthetase, alpha subunit; glycyl-tRNA ligase 5953292 17446145 AFR_27410 Actinoplanes friuliensis DSM 7358 glycyl-tRNA ligase YP_008736796.1 5950356 D 1246995 CDS YP_008736797.1 556568372 17446146 complement(5953309..5954046) 1 NC_022657.1 COG2207 AraC-type DNA-binding domain-containing proteins; AraC family transcriptional regulator 5954046 17446146 AFR_27415 Actinoplanes friuliensis DSM 7358 AraC family transcriptional regulator YP_008736797.1 5953309 R 1246995 CDS YP_008736798.1 556568373 17446147 5954137..5955303 1 NC_022657.1 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases; hypothetical protein 5955303 17446147 AFR_27420 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736798.1 5954137 D 1246995 CDS YP_008736799.1 556568374 17446148 5955305..5956015 1 NC_022657.1 COG2375 Siderophore-interacting protein; hypothetical protein 5956015 17446148 AFR_27425 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736799.1 5955305 D 1246995 CDS YP_008736800.1 556568375 17446149 complement(5956023..5956715) 1 NC_022657.1 hypothetical protein 5956715 17446149 AFR_27430 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736800.1 5956023 R 1246995 CDS YP_008736801.1 556568376 17446150 5956984..5958084 1 NC_022657.1 COG0584 Glycerophosphoryl diester phosphodiesterase; putative glycerophosphoryl diester phosphodiesterase 5958084 17446150 AFR_27435 Actinoplanes friuliensis DSM 7358 putative glycerophosphoryl diester phosphodiesterase YP_008736801.1 5956984 D 1246995 CDS YP_008736802.1 556568377 17446151 complement(5958081..5960255) 1 NC_022657.1 COG2771 DNA-binding HTH domain-containing proteins; putative LuxR-family transcriptional regulator 5960255 17446151 AFR_27440 Actinoplanes friuliensis DSM 7358 putative LuxR-family transcriptional regulator YP_008736802.1 5958081 R 1246995 CDS YP_008736803.1 556568378 17446152 complement(5960360..5961853) 1 NC_022657.1 COG0554 Glycerol kinase; glycerol kinase 5961853 glpK1 17446152 glpK1 Actinoplanes friuliensis DSM 7358 glycerol kinase YP_008736803.1 5960360 R 1246995 CDS YP_008736804.1 556568379 17446153 complement(5961872..5962579) 1 NC_022657.1 COG1414 Transcriptional regulator; IclR family transcriptional regulator 5962579 17446153 AFR_27450 Actinoplanes friuliensis DSM 7358 IclR family transcriptional regulator YP_008736804.1 5961872 R 1246995 CDS YP_008736805.1 556568380 17446154 5962781..5963593 1 NC_022657.1 COG0580 Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family); Aquaporin-4 5963593 17446154 AFR_27455 Actinoplanes friuliensis DSM 7358 Aquaporin-4 YP_008736805.1 5962781 D 1246995 CDS YP_008736806.1 556568381 17446155 5963586..5965103 1 NC_022657.1 COG0554 Glycerol kinase; glycerol kinase 5965103 glpK2 17446155 glpK2 Actinoplanes friuliensis DSM 7358 glycerol kinase YP_008736806.1 5963586 D 1246995 CDS YP_008736807.1 556568382 17446156 5965096..5966802 1 NC_022657.1 COG0578 Glycerol-3-phosphate dehydrogenase; putative glycerol-3-phosphate dehydrogenase 5966802 17446156 AFR_27465 Actinoplanes friuliensis DSM 7358 putative glycerol-3-phosphate dehydrogenase YP_008736807.1 5965096 D 1246995 CDS YP_008736808.1 556568383 17446157 complement(5966817..5967434) 1 NC_022657.1 hypothetical protein 5967434 17446157 AFR_27470 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736808.1 5966817 R 1246995 CDS YP_008736809.1 556568384 17446158 complement(5967484..5968236) 1 NC_022657.1 FR47 domain-containing protein 5968236 17446158 AFR_27475 Actinoplanes friuliensis DSM 7358 FR47 domain-containing protein YP_008736809.1 5967484 R 1246995 CDS YP_008736810.1 556568385 17446159 5968541..5969677 1 NC_022657.1 pectate lyase 5969677 17446159 AFR_27480 Actinoplanes friuliensis DSM 7358 pectate lyase YP_008736810.1 5968541 D 1246995 CDS YP_008736811.1 556568386 17446160 complement(5969693..5970202) 1 NC_022657.1 COG1309 Transcriptional regulator; putative TetR-family transcriptional regulator 5970202 17446160 AFR_27485 Actinoplanes friuliensis DSM 7358 putative TetR-family transcriptional regulator YP_008736811.1 5969693 R 1246995 CDS YP_008736812.1 556568387 17446161 5970279..5970680 1 NC_022657.1 COG3631 Ketosteroid isomerase-related protein; hypothetical protein 5970680 17446161 AFR_27490 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736812.1 5970279 D 1246995 CDS YP_008736813.1 556568388 17446162 complement(5970677..5971825) 1 NC_022657.1 COG1472 Beta-glucosidase-related glycosidases; Beta-N-acetylhexosaminidase 5971825 17446162 AFR_27495 Actinoplanes friuliensis DSM 7358 Beta-N-acetylhexosaminidase YP_008736813.1 5970677 R 1246995 CDS YP_008736814.1 556568389 17446163 complement(5971897..5973066) 1 NC_022657.1 hypothetical protein 5973066 17446163 AFR_27500 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736814.1 5971897 R 1246995 CDS YP_008736815.1 556568390 17446164 complement(5973154..5973570) 1 NC_022657.1 hypothetical protein 5973570 17446164 AFR_27505 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736815.1 5973154 R 1246995 CDS YP_008736816.1 556568391 17446165 complement(5973573..5974742) 1 NC_022657.1 COG3284 Transcriptional activator of acetoin/glycerol metabolism; putative Transcriptional activator of acetoin/glycerol metabolism 5974742 17446165 AFR_27510 Actinoplanes friuliensis DSM 7358 putative Transcriptional activator of acetoin/glycerol metabolism YP_008736816.1 5973573 R 1246995 CDS YP_008736817.1 556568392 17446166 5975658..5977412 1 NC_022657.1 COG2072 Predicted flavoprotein involved in K+ transport; oxidoreductase 5977412 17446166 AFR_27515 Actinoplanes friuliensis DSM 7358 oxidoreductase YP_008736817.1 5975658 D 1246995 CDS YP_008736818.1 556568393 17446167 complement(5977406..5978134) 1 NC_022657.1 COG1409 Predicted phosphohydrolases; cyclic nucleotide phosphodiesterase 5978134 17446167 AFR_27520 Actinoplanes friuliensis DSM 7358 cyclic nucleotide phosphodiesterase YP_008736818.1 5977406 R 1246995 CDS YP_008736819.1 556568394 17446168 complement(5978222..5978548) 1 NC_022657.1 hypothetical protein 5978548 17446168 AFR_27525 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736819.1 5978222 R 1246995 CDS YP_008736820.1 556568395 17446169 complement(5978557..5978868) 1 NC_022657.1 hypothetical protein 5978868 17446169 AFR_27530 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736820.1 5978557 R 1246995 CDS YP_008736821.1 556568396 17446170 complement(5978880..5980091) 1 NC_022657.1 COG0306 Phosphate/sulphate permeases; putative low-affinity inorganic phosphate transporter 5980091 17446170 AFR_27535 Actinoplanes friuliensis DSM 7358 putative low-affinity inorganic phosphate transporter YP_008736821.1 5978880 R 1246995 CDS YP_008736822.1 556568397 17446171 complement(5980334..5981635) 1 NC_022657.1 COG0160 4-aminobutyrate aminotransferase and related aminotransferases; class III aminotransferase 5981635 17446171 AFR_27540 Actinoplanes friuliensis DSM 7358 class III aminotransferase YP_008736822.1 5980334 R 1246995 CDS YP_008736823.1 556568398 17446172 complement(5981654..5983030) 1 NC_022657.1 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs; GntR family transcriptional regulator 5983030 17446172 AFR_27545 Actinoplanes friuliensis DSM 7358 GntR family transcriptional regulator YP_008736823.1 5981654 R 1246995 CDS YP_008736824.1 556568399 17446173 5983256..5984095 1 NC_022657.1 COG0388 Predicted amidohydrolase; putative carbon-nitrogen hydrolase 5984095 17446173 AFR_27550 Actinoplanes friuliensis DSM 7358 putative carbon-nitrogen hydrolase YP_008736824.1 5983256 D 1246995 CDS YP_008736825.1 556568400 17446174 5984092..5985492 1 NC_022657.1 COG0044 Dihydroorotase and related cyclic amidohydrolases; phenylhydantoinase 5985492 17446174 AFR_27555 Actinoplanes friuliensis DSM 7358 phenylhydantoinase YP_008736825.1 5984092 D 1246995 CDS YP_008736826.1 556568401 17446175 5985501..5986985 1 NC_022657.1 COG1012 NAD-dependent aldehyde dehydrogenases; methylmalonate-semialdehyde dehydrogenase 5986985 17446175 AFR_27560 Actinoplanes friuliensis DSM 7358 methylmalonate-semialdehyde dehydrogenase YP_008736826.1 5985501 D 1246995 CDS YP_008736827.1 556568402 17446176 5986991..5987986 1 NC_022657.1 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases; putative luciferase-like monooxygenase 5987986 17446176 AFR_27565 Actinoplanes friuliensis DSM 7358 putative luciferase-like monooxygenase YP_008736827.1 5986991 D 1246995 CDS YP_008736828.1 556568403 17446177 5987992..5988825 1 NC_022657.1 COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component; ABC transporter permease 5988825 17446177 AFR_27570 Actinoplanes friuliensis DSM 7358 ABC transporter permease YP_008736828.1 5987992 D 1246995 CDS YP_008736829.1 556568404 17446178 5988822..5989604 1 NC_022657.1 COG1116 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component; putative ABC transporter ATP-binding protein 5989604 17446178 AFR_27575 Actinoplanes friuliensis DSM 7358 putative ABC transporter ATP-binding protein YP_008736829.1 5988822 D 1246995 CDS YP_008736830.1 556568405 17446179 5989601..5990365 1 NC_022657.1 COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component; ABC transporter permease 5990365 17446179 AFR_27580 Actinoplanes friuliensis DSM 7358 ABC transporter permease YP_008736830.1 5989601 D 1246995 CDS YP_008736831.1 556568406 17446180 5990386..5991519 1 NC_022657.1 COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components; putative NMT1/THI5-like protein 5991519 17446180 AFR_27585 Actinoplanes friuliensis DSM 7358 putative NMT1/THI5-like protein YP_008736831.1 5990386 D 1246995 CDS YP_008736832.1 556568407 17446181 5991619..5992053 1 NC_022657.1 COG0346 Lactoylglutathione lyase and related lyases; Glyoxalase/bleomycin family protein 5992053 17446181 AFR_27590 Actinoplanes friuliensis DSM 7358 Glyoxalase/bleomycin family protein YP_008736832.1 5991619 D 1246995 CDS YP_008736833.1 556568408 17446182 complement(5992040..5992807) 1 NC_022657.1 hypothetical protein 5992807 17446182 AFR_27595 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736833.1 5992040 R 1246995 CDS YP_008736834.1 556568409 17446183 complement(5992905..5994983) 1 NC_022657.1 COG2133 Glucose/sorbosone dehydrogenases; hypothetical protein 5994983 17446183 AFR_27600 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736834.1 5992905 R 1246995 CDS YP_008736835.1 556568410 17446184 complement(5994996..5995922) 1 NC_022657.1 COG1082 Sugar phosphate isomerases/epimerases; hypothetical protein 5995922 17446184 AFR_27605 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736835.1 5994996 R 1246995 CDS YP_008736836.1 556568411 17446185 complement(5996240..5998543) 1 NC_022657.1 COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain; putative signaling protein 5998543 17446185 AFR_27610 Actinoplanes friuliensis DSM 7358 putative signaling protein YP_008736836.1 5996240 R 1246995 CDS YP_008736837.1 556568412 17446186 5998785..5999420 1 NC_022657.1 hypothetical protein 5999420 17446186 AFR_27615 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736837.1 5998785 D 1246995 CDS YP_008736838.1 556568413 17446187 complement(5999417..5999815) 1 NC_022657.1 hypothetical protein 5999815 17446187 AFR_27620 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736838.1 5999417 R 1246995 CDS YP_008736839.1 556568414 17446188 complement(5999854..6001092) 1 NC_022657.1 COG1940 Transcriptional regulator/sugar kinase; putative sugar kinase 6001092 17446188 AFR_27625 Actinoplanes friuliensis DSM 7358 putative sugar kinase YP_008736839.1 5999854 R 1246995 CDS YP_008736840.1 556568415 17446189 complement(6001209..6002309) 1 NC_022657.1 COG4213 ABC-type xylose transport system, periplasmic component; Multiple sugar-binding periplasmic receptor chvE 6002309 17446189 AFR_27630 Actinoplanes friuliensis DSM 7358 Multiple sugar-binding periplasmic receptor chvE YP_008736840.1 6001209 R 1246995 CDS YP_008736841.1 556568416 17446190 complement(6002368..6003666) 1 NC_022657.1 COG4214 ABC-type xylose transport system, permease component; putative multiple sugar transport system permease 6003666 17446190 AFR_27635 Actinoplanes friuliensis DSM 7358 putative multiple sugar transport system permease YP_008736841.1 6002368 R 1246995 CDS YP_008736842.1 556568417 17446191 complement(6003663..6005210) 1 NC_022657.1 COG1129 ABC-type sugar transport system, ATPase component; L-arabinose transport ATP-binding protein araG 6005210 17446191 AFR_27640 Actinoplanes friuliensis DSM 7358 L-arabinose transport ATP-binding protein araG YP_008736842.1 6003663 R 1246995 CDS YP_008736843.1 556568418 17446192 complement(6005395..6007569) 1 NC_022657.1 COG2409 Predicted drug exporters of the RND superfamily; MmpL domain-containing protein 6007569 17446192 AFR_27645 Actinoplanes friuliensis DSM 7358 MmpL domain-containing protein YP_008736843.1 6005395 R 1246995 CDS YP_008736844.1 556568419 17446193 complement(6007571..6008116) 1 NC_022657.1 COG1309 Transcriptional regulator; TetR family transcriptional regulator 6008116 17446193 AFR_27650 Actinoplanes friuliensis DSM 7358 TetR family transcriptional regulator YP_008736844.1 6007571 R 1246995 CDS YP_008736845.1 556568420 17446194 complement(6008209..6008616) 1 NC_022657.1 COG1846 Transcriptional regulators; MarR family transcriptional regulator 6008616 17446194 AFR_27655 Actinoplanes friuliensis DSM 7358 MarR family transcriptional regulator YP_008736845.1 6008209 R 1246995 CDS YP_008736846.1 556568421 17446195 6008702..6010498 1 NC_022657.1 COG1132 ABC-type multidrug transport system, ATPase and permease components; ABC transporter 6010498 17446195 AFR_27660 Actinoplanes friuliensis DSM 7358 ABC transporter YP_008736846.1 6008702 D 1246995 CDS YP_008736847.1 556568422 17446196 complement(6010533..6012296) 1 NC_022657.1 COG0642 Signal transduction histidine kinase; histidine kinase 6012296 17446196 AFR_27665 Actinoplanes friuliensis DSM 7358 histidine kinase YP_008736847.1 6010533 R 1246995 CDS YP_008736848.1 556568423 17446197 complement(6012298..6012969) 1 NC_022657.1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; two component transcriptional regulator 6012969 17446197 AFR_27670 Actinoplanes friuliensis DSM 7358 two component transcriptional regulator YP_008736848.1 6012298 R 1246995 CDS YP_008736849.1 556568424 17446198 6013084..6013638 1 NC_022657.1 hypothetical protein 6013638 17446198 AFR_27675 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736849.1 6013084 D 1246995 CDS YP_008736850.1 556568425 17446199 6013652..6014713 1 NC_022657.1 hypothetical protein 6014713 17446199 AFR_27680 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736850.1 6013652 D 1246995 CDS YP_008736851.1 556568426 17446200 6014710..6015390 1 NC_022657.1 COG1136 ABC-type antimicrobial peptide transport system, ATPase component; ABC transporter ATP-binding protein 6015390 17446200 AFR_27685 Actinoplanes friuliensis DSM 7358 ABC transporter ATP-binding protein YP_008736851.1 6014710 D 1246995 CDS YP_008736852.1 556568427 17446201 6015387..6016568 1 NC_022657.1 COG0577 ABC-type antimicrobial peptide transport system, permease component; ABC transporter permease 6016568 17446201 AFR_27690 Actinoplanes friuliensis DSM 7358 ABC transporter permease YP_008736852.1 6015387 D 1246995 CDS YP_008736853.1 556568428 17446202 complement(6016573..6017922) 1 NC_022657.1 COG1252 NADH dehydrogenase, FAD-containing subunit; NADH dehydrogenase 6017922 17446202 AFR_27695 Actinoplanes friuliensis DSM 7358 NADH dehydrogenase YP_008736853.1 6016573 R 1246995 CDS YP_008736854.1 556568429 17446203 6018101..6019507 1 NC_022657.1 COG0500 SAM-dependent methyltransferases; methyltransferase 6019507 17446203 AFR_27700 Actinoplanes friuliensis DSM 7358 methyltransferase YP_008736854.1 6018101 D 1246995 CDS YP_008736855.1 556568430 17446204 complement(6019642..6020895) 1 NC_022657.1 COG5659 FOG: Transposase; putative transposase 6020895 17446204 AFR_27705 Actinoplanes friuliensis DSM 7358 putative transposase YP_008736855.1 6019642 R 1246995 CDS YP_008736856.1 556568431 17446205 complement(6021127..6021933) 1 NC_022657.1 hydrolase 6021933 17446205 AFR_27710 Actinoplanes friuliensis DSM 7358 hydrolase YP_008736856.1 6021127 R 1246995 CDS YP_008736857.1 556568432 17446206 complement(6022065..6022418) 1 NC_022657.1 COG1725 Predicted transcriptional regulators; transcriptional regulator 6022418 17446206 AFR_27715 Actinoplanes friuliensis DSM 7358 transcriptional regulator YP_008736857.1 6022065 R 1246995 CDS YP_008736858.1 556568433 17446207 complement(6022415..6023170) 1 NC_022657.1 COG1126 ABC-type polar amino acid transport system, ATPase component; hypothetical protein 6023170 17446207 AFR_27720 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736858.1 6022415 R 1246995 CDS YP_008736859.1 556568434 17446208 complement(6023232..6025109) 1 NC_022657.1 COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases; propionyl-CoA synthetase 6025109 17446208 AFR_27725 Actinoplanes friuliensis DSM 7358 propionyl-CoA synthetase YP_008736859.1 6023232 R 1246995 CDS YP_008736860.1 556568435 17446209 complement(6025159..6030564) 1 NC_022657.1 COG0366 Glycosidases; alpha-1,6-glucosidase 6030564 17446209 AFR_27730 Actinoplanes friuliensis DSM 7358 alpha-1,6-glucosidase YP_008736860.1 6025159 R 1246995 CDS YP_008736861.1 556568436 17446210 6030709..6032622 1 NC_022657.1 COG0366 Glycosidases; putative glycosyl hydrolase 6032622 17446210 AFR_27735 Actinoplanes friuliensis DSM 7358 putative glycosyl hydrolase YP_008736861.1 6030709 D 1246995 CDS YP_008736862.1 556568437 17446211 complement(6032646..6033065) 1 NC_022657.1 hypothetical protein 6033065 17446211 AFR_27740 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736862.1 6032646 R 1246995 CDS YP_008736863.1 556568438 17446212 complement(6033141..6033977) 1 NC_022657.1 COG2375 Siderophore-interacting protein; putative siderophore-interacting protein 6033977 17446212 AFR_27745 Actinoplanes friuliensis DSM 7358 putative siderophore-interacting protein YP_008736863.1 6033141 R 1246995 CDS YP_008736864.1 556568439 17446213 complement(6033991..6034542) 1 NC_022657.1 hypothetical protein 6034542 17446213 AFR_27750 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736864.1 6033991 R 1246995 CDS YP_008736865.1 556568440 17446214 6034640..6035887 1 NC_022657.1 COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases; ferredoxin reductase 6035887 17446214 AFR_27755 Actinoplanes friuliensis DSM 7358 ferredoxin reductase YP_008736865.1 6034640 D 1246995 CDS YP_008736866.1 556568441 17446215 6035884..6036084 1 NC_022657.1 hypothetical protein 6036084 17446215 AFR_27760 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736866.1 6035884 D 1246995 CDS YP_008736867.1 556568442 17446216 6036081..6037712 1 NC_022657.1 COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit; putative FAD-dependent oxidoreductase 6037712 17446216 AFR_27765 Actinoplanes friuliensis DSM 7358 putative FAD-dependent oxidoreductase YP_008736867.1 6036081 D 1246995 CDS YP_008736868.1 556568443 17446217 6037827..6038795 1 NC_022657.1 COG0392 Predicted integral membrane protein; hypothetical protein 6038795 17446217 AFR_27770 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736868.1 6037827 D 1246995 CDS YP_008736869.1 556568444 17446218 complement(6038770..6041109) 1 NC_022657.1 COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; putative oxidoreductase 6041109 17446218 AFR_27775 Actinoplanes friuliensis DSM 7358 putative oxidoreductase YP_008736869.1 6038770 R 1246995 CDS YP_008736870.1 556568445 17446219 6041279..6042715 1 NC_022657.1 COG1012 NAD-dependent aldehyde dehydrogenases; putative aldehyde dehydrogenase 6042715 17446219 AFR_27780 Actinoplanes friuliensis DSM 7358 putative aldehyde dehydrogenase YP_008736870.1 6041279 D 1246995 CDS YP_008736871.1 556568446 17446220 6042712..6043998 1 NC_022657.1 COG0160 4-aminobutyrate aminotransferase and related aminotransferases; putative aminotransferase 6043998 17446220 AFR_27785 Actinoplanes friuliensis DSM 7358 putative aminotransferase YP_008736871.1 6042712 D 1246995 CDS YP_008736872.1 556568447 17446221 complement(6043972..6045177) 1 NC_022657.1 COG1748 Saccharopine dehydrogenase and related proteins; saccharopine dehydrogenase 6045177 17446221 AFR_27790 Actinoplanes friuliensis DSM 7358 saccharopine dehydrogenase YP_008736872.1 6043972 R 1246995 CDS YP_008736873.1 556568448 17446222 6045434..6045889 1 NC_022657.1 COG1522 Transcriptional regulators; putative AsnC-family transcriptional regulator 6045889 17446222 AFR_27795 Actinoplanes friuliensis DSM 7358 putative AsnC-family transcriptional regulator YP_008736873.1 6045434 D 1246995 CDS YP_008736874.1 556568449 17446223 6045886..6047253 1 NC_022657.1 COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; hypothetical protein 6047253 17446223 AFR_27800 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736874.1 6045886 D 1246995 CDS YP_008736875.1 556568450 17446224 6047325..6048539 1 NC_022657.1 COG0665 Glycine/D-amino acid oxidases (deaminating); putative FAD-dependent oxidoreductase 6048539 17446224 AFR_27805 Actinoplanes friuliensis DSM 7358 putative FAD-dependent oxidoreductase YP_008736875.1 6047325 D 1246995 CDS YP_008736876.1 556568451 17446225 6049264..6049803 1 NC_022657.1 COG0702 Predicted nucleoside-diphosphate-sugar epimerases; hypothetical protein 6049803 17446225 AFR_27810 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736876.1 6049264 D 1246995 CDS YP_008736877.1 556568452 17446226 6049889..6050098 1 NC_022657.1 hypothetical protein 6050098 17446226 AFR_27815 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736877.1 6049889 D 1246995 CDS YP_008736878.1 556568453 17446227 complement(6050103..6052166) 1 NC_022657.1 COG0515 Serine/threonine protein kinase; serine/threonine-protein kinase-like domain-containing protein 6052166 17446227 AFR_27820 Actinoplanes friuliensis DSM 7358 serine/threonine-protein kinase-like domain-containing protein YP_008736878.1 6050103 R 1246995 CDS YP_008736879.1 556568454 17446228 6052296..6053111 1 NC_022657.1 hypothetical protein 6053111 17446228 AFR_27825 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736879.1 6052296 D 1246995 CDS YP_008736880.1 556568455 17446229 6053108..6053491 1 NC_022657.1 COG1725 Predicted transcriptional regulators; Histidine utilization repressor 6053491 17446229 AFR_27830 Actinoplanes friuliensis DSM 7358 Histidine utilization repressor YP_008736880.1 6053108 D 1246995 CDS YP_008736881.1 556568456 17446230 6053510..6053878 1 NC_022657.1 hypothetical protein 6053878 17446230 AFR_27835 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736881.1 6053510 D 1246995 CDS YP_008736882.1 556568457 17446231 6053945..6054523 1 NC_022657.1 NUDIX hydrolase 6054523 17446231 AFR_27840 Actinoplanes friuliensis DSM 7358 NUDIX hydrolase YP_008736882.1 6053945 D 1246995 CDS YP_008736883.1 556568458 17446232 complement(6054528..6055373) 1 NC_022657.1 COG2755 Lysophospholipase L1 and related esterases; putative GDSL-like lipase/acylhydrolase 6055373 17446232 AFR_27845 Actinoplanes friuliensis DSM 7358 putative GDSL-like lipase/acylhydrolase YP_008736883.1 6054528 R 1246995 CDS YP_008736884.1 556568459 17446233 6055528..6056853 1 NC_022657.1 COG1621 Beta-fructosidases (levanase/invertase); alpha l-arabinofuranosidase 6056853 17446233 AFR_27850 Actinoplanes friuliensis DSM 7358 alpha l-arabinofuranosidase YP_008736884.1 6055528 D 1246995 CDS YP_008736885.1 556568460 17446234 complement(6056861..6058249) 1 NC_022657.1 COG1680 Beta-lactamase class C and other penicillin binding proteins; beta-lactamase class C-like protein 6058249 17446234 AFR_27855 Actinoplanes friuliensis DSM 7358 beta-lactamase class C-like protein YP_008736885.1 6056861 R 1246995 CDS YP_008736886.1 556568461 17446235 complement(6058294..6058716) 1 NC_022657.1 hypothetical protein 6058716 17446235 AFR_27860 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736886.1 6058294 R 1246995 CDS YP_008736887.1 556568462 17446236 complement(6058762..6060003) 1 NC_022657.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); putative prolyl aminopeptidase 6060003 17446236 AFR_27865 Actinoplanes friuliensis DSM 7358 putative prolyl aminopeptidase YP_008736887.1 6058762 R 1246995 CDS YP_008736888.1 556568463 17446237 6060063..6060623 1 NC_022657.1 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins; hypothetical protein 6060623 17446237 AFR_27870 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736888.1 6060063 D 1246995 CDS YP_008736889.1 556568464 17446238 6060885..6062003 1 NC_022657.1 COG0438 Glycosyltransferase; putative glycosyltransferase 6062003 17446238 AFR_27875 Actinoplanes friuliensis DSM 7358 putative glycosyltransferase YP_008736889.1 6060885 D 1246995 CDS YP_008736890.1 556568465 17446239 6062000..6063019 1 NC_022657.1 putative glycosyltransferase 6063019 17446239 AFR_27880 Actinoplanes friuliensis DSM 7358 putative glycosyltransferase YP_008736890.1 6062000 D 1246995 CDS YP_008736891.1 556568466 17446240 6063019..6063417 1 NC_022657.1 putative RNA polymerase ECF subfamily sigma factor 6063417 17446240 AFR_27885 Actinoplanes friuliensis DSM 7358 putative RNA polymerase ECF subfamily sigma factor YP_008736891.1 6063019 D 1246995 CDS YP_008736892.1 556568467 17446241 complement(6063421..6064188) 1 NC_022657.1 hypothetical protein 6064188 17446241 AFR_27890 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736892.1 6063421 R 1246995 CDS YP_008736893.1 556568468 17446242 complement(6064230..6065339) 1 NC_022657.1 COG1804 Predicted acyl-CoA transferases/carnitine dehydratase; L-carnitine dehydratase/bile acid-inducible protein F 6065339 17446242 AFR_27895 Actinoplanes friuliensis DSM 7358 L-carnitine dehydratase/bile acid-inducible protein F YP_008736893.1 6064230 R 1246995 CDS YP_008736894.1 556568469 17446243 6065381..6066052 1 NC_022657.1 acetoacetate decarboxylase 6066052 17446243 AFR_27900 Actinoplanes friuliensis DSM 7358 acetoacetate decarboxylase YP_008736894.1 6065381 D 1246995 CDS YP_008736895.1 556568470 17446244 complement(6066019..6066672) 1 NC_022657.1 hypothetical protein 6066672 17446244 AFR_27905 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736895.1 6066019 R 1246995 CDS YP_008736896.1 556568471 17446245 complement(6066684..6067421) 1 NC_022657.1 CalS11 6067421 17446245 AFR_27910 Actinoplanes friuliensis DSM 7358 CalS11 YP_008736896.1 6066684 R 1246995 CDS YP_008736897.1 556568472 17446246 6067576..6068895 1 NC_022657.1 COG1680 Beta-lactamase class C and other penicillin binding proteins; putative beta-lactamase 6068895 17446246 AFR_27915 Actinoplanes friuliensis DSM 7358 putative beta-lactamase YP_008736897.1 6067576 D 1246995 CDS YP_008736898.1 556568473 17446247 complement(6068902..6069786) 1 NC_022657.1 COG1396 Predicted transcriptional regulators; MmyB family DNA-binding protein 6069786 17446247 AFR_27920 Actinoplanes friuliensis DSM 7358 MmyB family DNA-binding protein YP_008736898.1 6068902 R 1246995 CDS YP_008736899.1 556568474 17446248 6069933..6070727 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); short-chain dehydrogenase/reductase SDR 6070727 17446248 AFR_27925 Actinoplanes friuliensis DSM 7358 short-chain dehydrogenase/reductase SDR YP_008736899.1 6069933 D 1246995 CDS YP_008736900.1 556568475 17446249 complement(6070738..6072477) 1 NC_022657.1 COG0515 Serine/threonine protein kinase; serine/threonine protein kinase 6072477 17446249 AFR_27930 Actinoplanes friuliensis DSM 7358 serine/threonine protein kinase YP_008736900.1 6070738 R 1246995 CDS YP_008736901.1 556568476 17446250 6072749..6073426 1 NC_022657.1 COG2170 Uncharacterized conserved protein; glutamate--cysteine ligase gCS2 6073426 17446250 AFR_27935 Actinoplanes friuliensis DSM 7358 glutamate--cysteine ligase gCS2 YP_008736901.1 6072749 D 1246995 CDS YP_008736902.1 556568477 17446251 6073510..6074910 1 NC_022657.1 hypothetical protein 6074910 17446251 AFR_27940 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736902.1 6073510 D 1246995 CDS YP_008736903.1 556568478 17446252 complement(6074918..6076687) 1 NC_022657.1 COG3276 Selenocysteine-specific translation elongation factor; selenocysteine-specific translation elongation factor 6076687 17446252 AFR_27945 Actinoplanes friuliensis DSM 7358 selenocysteine-specific translation elongation factor YP_008736903.1 6074918 R 1246995 CDS YP_008736904.1 556568479 17446253 complement(6076689..6077981) 1 NC_022657.1 COG1921 Selenocysteine synthase [seryl-tRNASer selenium transferase]; selenocysteine synthase 6077981 17446253 AFR_27950 Actinoplanes friuliensis DSM 7358 selenocysteine synthase YP_008736904.1 6076689 R 1246995 CDS YP_008736905.1 556568480 17446255 6078190..6079200 1 NC_022657.1 COG0709 Selenophosphate synthase; selenide, water dikinase 6079200 17446255 AFR_27955 Actinoplanes friuliensis DSM 7358 selenide, water dikinase YP_008736905.1 6078190 D 1246995 CDS YP_008736906.1 556568481 17446256 complement(6079202..6080122) 1 NC_022657.1 NrfD-like protein 6080122 17446256 AFR_27960 Actinoplanes friuliensis DSM 7358 NrfD-like protein YP_008736906.1 6079202 R 1246995 CDS YP_008736907.1 556568482 17446257 complement(6080281..6081312) 1 NC_022657.1 COG0437 Fe-S-cluster-containing hydrogenase components 1; formate dehydrogenase subunit beta 6081312 17446257 AFR_27965 Actinoplanes friuliensis DSM 7358 formate dehydrogenase subunit beta YP_008736907.1 6080281 R 1246995 CDS YP_008736908.1 556568483 17446258 complement(6081314..6083875) 1 NC_022657.1 COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; formate dehydrogenase subunit alpha 6083875 17446258 AFR_27970 Actinoplanes friuliensis DSM 7358 formate dehydrogenase subunit alpha YP_008736908.1 6081314 R 1246995 CDS YP_008736909.1 556568484 17446259 complement(6083984..6084553) 1 NC_022657.1 COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; putative molybdopterin oxidoreductase Fe4s4 domain protein 6084553 17446259 AFR_27975 Actinoplanes friuliensis DSM 7358 putative molybdopterin oxidoreductase Fe4s4 domain protein YP_008736909.1 6083984 R 1246995 CDS YP_008736910.1 556568485 17446260 6084793..6085512 1 NC_022657.1 COG2203 FOG: GAF domain; hypothetical protein 6085512 17446260 AFR_27980 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736910.1 6084793 D 1246995 CDS YP_008736911.1 556568486 17446261 6085590..6086168 1 NC_022657.1 hypothetical protein 6086168 17446261 AFR_27985 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736911.1 6085590 D 1246995 CDS YP_008736912.1 556568487 17446262 6086159..6087532 1 NC_022657.1 COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II; acyl-CoA synthetase 6087532 17446262 AFR_27990 Actinoplanes friuliensis DSM 7358 acyl-CoA synthetase YP_008736912.1 6086159 D 1246995 CDS YP_008736913.1 556568488 17446263 complement(6087537..6088319) 1 NC_022657.1 hypothetical protein 6088319 17446263 AFR_27995 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736913.1 6087537 R 1246995 CDS YP_008736914.1 556568489 17446264 complement(6088511..6088735) 1 NC_022657.1 COG1141 Ferredoxin; hypothetical protein 6088735 17446264 AFR_28000 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736914.1 6088511 R 1246995 CDS YP_008736915.1 556568490 17446265 complement(6088732..6089940) 1 NC_022657.1 COG2124 Cytochrome P450; cytochrome P450-like enzyme 6089940 17446265 AFR_28005 Actinoplanes friuliensis DSM 7358 cytochrome P450-like enzyme YP_008736915.1 6088732 R 1246995 CDS YP_008736916.1 556568491 17446266 6090193..6090855 1 NC_022657.1 hypothetical protein 6090855 17446266 AFR_28010 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736916.1 6090193 D 1246995 CDS YP_008736917.1 556568492 17446267 6090932..6091825 1 NC_022657.1 COG1715 Restriction endonuclease; 5-methylcytosine-specific restriction endonuclease 6091825 17446267 AFR_28015 Actinoplanes friuliensis DSM 7358 5-methylcytosine-specific restriction endonuclease YP_008736917.1 6090932 D 1246995 CDS YP_008736918.1 556568493 17446268 complement(6091822..6092943) 1 NC_022657.1 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases; FAD-binding monooxygenase 6092943 17446268 AFR_28020 Actinoplanes friuliensis DSM 7358 FAD-binding monooxygenase YP_008736918.1 6091822 R 1246995 CDS YP_008736919.1 556568494 17446269 6093013..6093645 1 NC_022657.1 COG1309 Transcriptional regulator; TetR-family transcriptional regulator 6093645 17446269 AFR_28025 Actinoplanes friuliensis DSM 7358 TetR-family transcriptional regulator YP_008736919.1 6093013 D 1246995 CDS YP_008736920.1 556568495 17446270 complement(6093590..6094477) 1 NC_022657.1 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases; luciferase-like monooxygenase 6094477 17446270 AFR_28030 Actinoplanes friuliensis DSM 7358 luciferase-like monooxygenase YP_008736920.1 6093590 R 1246995 CDS YP_008736921.1 556568496 17446271 6094549..6096801 1 NC_022657.1 COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain; putative signaling protein 6096801 17446271 AFR_28035 Actinoplanes friuliensis DSM 7358 putative signaling protein YP_008736921.1 6094549 D 1246995 CDS YP_008736922.1 556568497 17446272 6096854..6097825 1 NC_022657.1 hypothetical protein 6097825 17446272 AFR_28040 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736922.1 6096854 D 1246995 CDS YP_008736923.1 556568498 17446273 complement(6097917..6100118) 1 NC_022657.1 COG2409 Predicted drug exporters of the RND superfamily; RND superfamily drug exporter-like protein 6100118 17446273 AFR_28045 Actinoplanes friuliensis DSM 7358 RND superfamily drug exporter-like protein YP_008736923.1 6097917 R 1246995 CDS YP_008736924.1 556568499 17446274 6100413..6101096 1 NC_022657.1 hypothetical protein 6101096 17446274 AFR_28050 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736924.1 6100413 D 1246995 CDS YP_008736925.1 556568500 17446275 6101136..6102161 1 NC_022657.1 COG3386 Gluconolactonase; Strictosidine synthase, conserved region 6102161 17446275 AFR_28055 Actinoplanes friuliensis DSM 7358 Strictosidine synthase, conserved region YP_008736925.1 6101136 D 1246995 CDS YP_008736926.1 556568501 17446276 6102290..6103198 1 NC_022657.1 hypothetical protein 6103198 17446276 AFR_28060 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736926.1 6102290 D 1246995 CDS YP_008736927.1 556568502 17446277 6103200..6104381 1 NC_022657.1 COG1680 Beta-lactamase class C and other penicillin binding proteins; 6-aminohexanoate-dimer hydrolase 6104381 17446277 AFR_28065 Actinoplanes friuliensis DSM 7358 6-aminohexanoate-dimer hydrolase YP_008736927.1 6103200 D 1246995 CDS YP_008736928.1 556568503 17446278 6104469..6105584 1 NC_022657.1 Lipase 6 6105584 17446278 AFR_28070 Actinoplanes friuliensis DSM 7358 Lipase 6 YP_008736928.1 6104469 D 1246995 CDS YP_008736929.1 556568504 17446279 6105675..6106133 1 NC_022657.1 hypothetical protein 6106133 17446279 AFR_28075 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736929.1 6105675 D 1246995 CDS YP_008736930.1 556568505 17446280 6106143..6106940 1 NC_022657.1 COG3358 Uncharacterized conserved protein; hypothetical protein 6106940 17446280 AFR_28080 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736930.1 6106143 D 1246995 CDS YP_008736931.1 556568506 17446281 6106986..6107171 1 NC_022657.1 hypothetical protein 6107171 17446281 AFR_28085 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736931.1 6106986 D 1246995 CDS YP_008736932.1 556568507 17446282 complement(6107508..6109214) 1 NC_022657.1 COG0612 Predicted Zn-dependent peptidases; peptidase M16 domain-containing protein 6109214 17446282 AFR_28090 Actinoplanes friuliensis DSM 7358 peptidase M16 domain-containing protein YP_008736932.1 6107508 R 1246995 CDS YP_008736933.1 556568508 17446283 complement(6109211..6110182) 1 NC_022657.1 hypothetical protein 6110182 17446283 AFR_28095 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736933.1 6109211 R 1246995 CDS YP_008736934.1 556568509 17446284 6110249..6111364 1 NC_022657.1 hypothetical protein 6111364 17446284 AFR_28100 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736934.1 6110249 D 1246995 CDS YP_008736935.1 556568510 17446285 complement(6111335..6111847) 1 NC_022657.1 hypothetical protein 6111847 17446285 AFR_28105 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736935.1 6111335 R 1246995 CDS YP_008736936.1 556568511 17446286 complement(6111918..6114455) 1 NC_022657.1 COG2866 Predicted carboxypeptidase; putative carboxypeptidase 6114455 17446286 AFR_28110 Actinoplanes friuliensis DSM 7358 putative carboxypeptidase YP_008736936.1 6111918 R 1246995 CDS YP_008736937.1 556568512 17446287 6114739..6115698 1 NC_022657.1 COG2113 ABC-type proline/glycine betaine transport systems, periplasmic components; glycine betaine ABC transporter substrate-binding protein 6115698 17446287 AFR_28115 Actinoplanes friuliensis DSM 7358 glycine betaine ABC transporter substrate-binding protein YP_008736937.1 6114739 D 1246995 CDS YP_008736938.1 556568513 17446288 6116116..6118584 1 NC_022657.1 COG0642 Signal transduction histidine kinase; sensor protein 6118584 17446288 AFR_28120 Actinoplanes friuliensis DSM 7358 sensor protein YP_008736938.1 6116116 D 1246995 CDS YP_008736939.1 556568514 17446289 6118615..6119040 1 NC_022657.1 COG2018 Uncharacterized distant relative of homeotic protein bithoraxoid; hypothetical protein 6119040 17446289 AFR_28125 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736939.1 6118615 D 1246995 CDS YP_008736940.1 556568515 17446290 6119160..6119474 1 NC_022657.1 hypothetical protein 6119474 17446290 AFR_28130 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736940.1 6119160 D 1246995 CDS YP_008736941.1 556568516 17446291 6119458..6120072 1 NC_022657.1 COG2229 Predicted GTPase; hypothetical protein 6120072 17446291 AFR_28135 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736941.1 6119458 D 1246995 CDS YP_008736942.1 556568517 17446292 6120099..6121052 1 NC_022657.1 COG2113 ABC-type proline/glycine betaine transport systems, periplasmic components; glycine betaine ABC transporter substrate-binding protein 6121052 17446292 AFR_28140 Actinoplanes friuliensis DSM 7358 glycine betaine ABC transporter substrate-binding protein YP_008736942.1 6120099 D 1246995 CDS YP_008736943.1 556568518 17446293 complement(6121057..6122559) 1 NC_022657.1 COG2199 FOG: GGDEF domain; putative signaling protein 6122559 17446293 AFR_28145 Actinoplanes friuliensis DSM 7358 putative signaling protein YP_008736943.1 6121057 R 1246995 CDS YP_008736944.1 556568519 17446294 complement(6122549..6123955) 1 NC_022657.1 hypothetical protein 6123955 17446294 AFR_28150 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736944.1 6122549 R 1246995 CDS YP_008736945.1 556568520 17446295 complement(6123961..6124308) 1 NC_022657.1 hypothetical protein 6124308 17446295 AFR_28155 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736945.1 6123961 R 1246995 CDS YP_008736946.1 556568521 17446296 complement(6124317..6124709) 1 NC_022657.1 COG0653 Preprotein translocase subunit SecA (ATPase, RNA helicase); hypothetical protein 6124709 17446296 AFR_28160 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736946.1 6124317 R 1246995 CDS YP_008736947.1 556568522 17446297 complement(6124685..6125479) 1 NC_022657.1 hypothetical protein 6125479 17446297 AFR_28165 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736947.1 6124685 R 1246995 CDS YP_008736948.1 556568523 17446298 complement(6125470..6126615) 1 NC_022657.1 COG1160 Predicted GTPases; hypothetical protein 6126615 17446298 AFR_28170 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736948.1 6125470 R 1246995 CDS YP_008736949.1 556568524 17446299 complement(6126612..6128780) 1 NC_022657.1 hypothetical protein 6128780 17446299 AFR_28175 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736949.1 6126612 R 1246995 CDS YP_008736950.1 556568525 17446300 6129100..6129438 1 NC_022657.1 COG3152 Predicted membrane protein; hypothetical protein 6129438 17446300 AFR_28180 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736950.1 6129100 D 1246995 CDS YP_008736951.1 556568526 17446301 6129435..6129902 1 NC_022657.1 hypothetical protein 6129902 17446301 AFR_28185 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736951.1 6129435 D 1246995 CDS YP_008736952.1 556568527 17446302 6129933..6131204 1 NC_022657.1 COG0515 Serine/threonine protein kinase; serine/threonine protein kinase 6131204 17446302 AFR_28190 Actinoplanes friuliensis DSM 7358 serine/threonine protein kinase YP_008736952.1 6129933 D 1246995 CDS YP_008736953.1 556568528 17446303 complement(6131177..6133246) 1 NC_022657.1 COG1305 Transglutaminase-like enzymes, putative cysteine proteases; transglutaminase domain-containing protein 6133246 17446303 AFR_28195 Actinoplanes friuliensis DSM 7358 transglutaminase domain-containing protein YP_008736953.1 6131177 R 1246995 CDS YP_008736954.1 556568529 17446304 complement(6133243..6134352) 1 NC_022657.1 COG1721 Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain); hypothetical protein 6134352 17446304 AFR_28200 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736954.1 6133243 R 1246995 CDS YP_008736955.1 556568530 17446305 complement(6134355..6135311) 1 NC_022657.1 COG0714 MoxR-like ATPases; ATPase 6135311 17446305 AFR_28205 Actinoplanes friuliensis DSM 7358 ATPase YP_008736955.1 6134355 R 1246995 CDS YP_008736956.1 556568531 17446306 complement(6135308..6137107) 1 NC_022657.1 Fibronectin type III domain-containing protein 6137107 17446306 AFR_28210 Actinoplanes friuliensis DSM 7358 Fibronectin type III domain-containing protein YP_008736956.1 6135308 R 1246995 CDS YP_008736957.1 556568532 17446307 complement(6137249..6138496) 1 NC_022657.1 COG0642 Signal transduction histidine kinase; histidine kinase 6138496 17446307 AFR_28215 Actinoplanes friuliensis DSM 7358 histidine kinase YP_008736957.1 6137249 R 1246995 CDS YP_008736958.1 556568533 17446308 complement(6138493..6139152) 1 NC_022657.1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; winged helix family two component transcriptional regulator 6139152 17446308 AFR_28220 Actinoplanes friuliensis DSM 7358 winged helix family two component transcriptional regulator YP_008736958.1 6138493 R 1246995 CDS YP_008736959.1 556568534 17446309 6139214..6140845 1 NC_022657.1 COG3629 DNA-binding transcriptional activator of the SARP family; SARP family transcriptional regulator 6140845 17446309 AFR_28225 Actinoplanes friuliensis DSM 7358 SARP family transcriptional regulator YP_008736959.1 6139214 D 1246995 CDS YP_008736960.1 556568535 17446310 6140842..6141465 1 NC_022657.1 TrmB family transcriptional regulator 6141465 17446310 AFR_28230 Actinoplanes friuliensis DSM 7358 TrmB family transcriptional regulator YP_008736960.1 6140842 D 1246995 CDS YP_008736961.1 556568536 17446311 6141470..6142123 1 NC_022657.1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; winged helix family two component transcriptional regulator 6142123 17446311 AFR_28235 Actinoplanes friuliensis DSM 7358 winged helix family two component transcriptional regulator YP_008736961.1 6141470 D 1246995 CDS YP_008736962.1 556568537 17446312 complement(6142108..6142407) 1 NC_022657.1 COG1733 Predicted transcriptional regulators; transcriptional regulatory protein 6142407 17446312 AFR_28240 Actinoplanes friuliensis DSM 7358 transcriptional regulatory protein YP_008736962.1 6142108 R 1246995 CDS YP_008736963.1 556568538 17446313 6142539..6143165 1 NC_022657.1 COG0477 Permeases of the major facilitator superfamily; hypothetical protein 6143165 17446313 AFR_28245 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736963.1 6142539 D 1246995 CDS YP_008736964.1 556568539 17446314 complement(6143128..6144546) 1 NC_022657.1 hypothetical protein 6144546 17446314 AFR_28250 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736964.1 6143128 R 1246995 CDS YP_008736965.1 556568540 17446315 complement(6144628..6144987) 1 NC_022657.1 COG3801 Uncharacterized protein conserved in bacteria; hypothetical protein 6144987 17446315 AFR_28255 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736965.1 6144628 R 1246995 CDS YP_008736966.1 556568541 17446316 complement(6145040..6147064) 1 NC_022657.1 COG3534 Alpha-L-arabinofuranosidase; cellulose-binding family II protein 6147064 17446316 AFR_28260 Actinoplanes friuliensis DSM 7358 cellulose-binding family II protein YP_008736966.1 6145040 R 1246995 CDS YP_008736967.1 556568542 17446317 6147205..6147723 1 NC_022657.1 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; putative RNA polymerase ECF-subfamily sigma factor 6147723 17446317 AFR_28265 Actinoplanes friuliensis DSM 7358 putative RNA polymerase ECF-subfamily sigma factor YP_008736967.1 6147205 D 1246995 CDS YP_008736968.1 556568543 17446318 6147716..6148861 1 NC_022657.1 COG5563 Predicted integral membrane proteins containing uncharacterized repeats; hypothetical protein 6148861 17446318 AFR_28270 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736968.1 6147716 D 1246995 CDS YP_008736969.1 556568544 17446319 6148878..6150557 1 NC_022657.1 COG0397 Uncharacterized conserved protein; hypothetical protein 6150557 17446319 AFR_28275 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736969.1 6148878 D 1246995 CDS YP_008736970.1 556568545 17446320 complement(6150562..6151350) 1 NC_022657.1 hypothetical protein 6151350 17446320 AFR_28280 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736970.1 6150562 R 1246995 CDS YP_008736971.1 556568546 17446321 complement(6151484..6152479) 1 NC_022657.1 hypothetical protein 6152479 17446321 AFR_28285 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736971.1 6151484 R 1246995 CDS YP_008736972.1 556568547 17446322 6152703..6154088 1 NC_022657.1 hypothetical protein 6154088 17446322 AFR_28290 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736972.1 6152703 D 1246995 CDS YP_008736973.1 556568548 17446323 6154750..6155970 1 NC_022657.1 COG1520 FOG: WD40-like repeat; hypothetical protein 6155970 17446323 AFR_28295 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736973.1 6154750 D 1246995 CDS YP_008736974.1 556568549 17446324 complement(6155987..6156874) 1 NC_022657.1 hypothetical protein 6156874 17446324 AFR_28300 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736974.1 6155987 R 1246995 CDS YP_008736975.1 556568550 17446325 6157116..6158468 1 NC_022657.1 COG0477 Permeases of the major facilitator superfamily; Sugar efflux transporter B 6158468 17446325 AFR_28305 Actinoplanes friuliensis DSM 7358 Sugar efflux transporter B YP_008736975.1 6157116 D 1246995 CDS YP_008736976.1 556568551 17446326 complement(6158458..6160068) 1 NC_022657.1 COG3469 Chitinase; chitinase 6160068 17446326 AFR_28310 Actinoplanes friuliensis DSM 7358 chitinase YP_008736976.1 6158458 R 1246995 CDS YP_008736977.1 556568552 17446327 6160255..6163275 1 NC_022657.1 COG1215 Glycosyltransferases, probably involved in cell wall biogenesis; putative cellulose synthase A catalytic subunit 2 6163275 17446327 AFR_28315 Actinoplanes friuliensis DSM 7358 putative cellulose synthase A catalytic subunit 2 YP_008736977.1 6160255 D 1246995 CDS YP_008736978.1 556568553 17446328 complement(6163276..6163908) 1 NC_022657.1 COG1309 Transcriptional regulator; TetR family transcriptional regulator 6163908 17446328 AFR_28320 Actinoplanes friuliensis DSM 7358 TetR family transcriptional regulator YP_008736978.1 6163276 R 1246995 CDS YP_008736979.1 556568554 17446329 6163965..6164876 1 NC_022657.1 COG1680 Beta-lactamase class C and other penicillin binding proteins; beta-lactamase 6164876 17446329 AFR_28325 Actinoplanes friuliensis DSM 7358 beta-lactamase YP_008736979.1 6163965 D 1246995 CDS YP_008736980.1 556568555 17446330 6164894..6165370 1 NC_022657.1 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; GCN5-like N-acetyltransferase 6165370 17446330 AFR_28330 Actinoplanes friuliensis DSM 7358 GCN5-like N-acetyltransferase YP_008736980.1 6164894 D 1246995 CDS YP_008736981.1 556568556 17446331 6165382..6166020 1 NC_022657.1 hypothetical protein 6166020 17446331 AFR_28335 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736981.1 6165382 D 1246995 CDS YP_008736982.1 556568557 17446332 6166210..6168939 1 NC_022657.1 COG3899 Predicted ATPase; LuxR family transcriptional regulator 6168939 17446332 AFR_28340 Actinoplanes friuliensis DSM 7358 LuxR family transcriptional regulator YP_008736982.1 6166210 D 1246995 CDS YP_008736983.1 556568558 17446333 6169006..6170175 1 NC_022657.1 hypothetical protein 6170175 17446333 AFR_28345 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736983.1 6169006 D 1246995 CDS YP_008736984.1 556568559 17446334 6170271..6170816 1 NC_022657.1 hypothetical protein 6170816 17446334 AFR_28350 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736984.1 6170271 D 1246995 CDS YP_008736985.1 556568560 17446335 6171318..6171674 1 NC_022657.1 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); Anti-sigma F factor antagonist 6171674 17446335 AFR_28355 Actinoplanes friuliensis DSM 7358 Anti-sigma F factor antagonist YP_008736985.1 6171318 D 1246995 CDS YP_008736986.1 556568561 17446336 6171685..6173094 1 NC_022657.1 COG1012 NAD-dependent aldehyde dehydrogenases; succinic semialdehyde dehydrogenase 6173094 gabD1 17446336 gabD1 Actinoplanes friuliensis DSM 7358 succinic semialdehyde dehydrogenase YP_008736986.1 6171685 D 1246995 CDS YP_008736987.1 556568562 17446337 6173168..6174418 1 NC_022657.1 COG2124 Cytochrome P450; CypC protein 6174418 17446337 AFR_28365 Actinoplanes friuliensis DSM 7358 CypC protein YP_008736987.1 6173168 D 1246995 CDS YP_008736988.1 556568563 17446338 complement(6174459..6174725) 1 NC_022657.1 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); anti-sigma factor antagonist 6174725 17446338 AFR_28370 Actinoplanes friuliensis DSM 7358 anti-sigma factor antagonist YP_008736988.1 6174459 R 1246995 CDS YP_008736989.1 556568564 17446339 complement(6174850..6176031) 1 NC_022657.1 COG1960 Acyl-CoA dehydrogenases; acyl-CoA dehydrogenase domain-containing protein 6176031 17446339 AFR_28375 Actinoplanes friuliensis DSM 7358 acyl-CoA dehydrogenase domain-containing protein YP_008736989.1 6174850 R 1246995 CDS YP_008736990.1 556568565 17446340 6176075..6177766 1 NC_022657.1 hypothetical protein 6177766 17446340 AFR_28380 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736990.1 6176075 D 1246995 CDS YP_008736991.1 556568566 17446341 6177763..6179361 1 NC_022657.1 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta); acetyl/propionyl-CoA carboxylase subunit beta 6179361 17446341 AFR_28385 Actinoplanes friuliensis DSM 7358 acetyl/propionyl-CoA carboxylase subunit beta YP_008736991.1 6177763 D 1246995 CDS YP_008736992.1 556568567 17446342 6179367..6181304 1 NC_022657.1 COG0439 Biotin carboxylase; acyl-CoA carboxylase alpha chain 6181304 17446342 AFR_28390 Actinoplanes friuliensis DSM 7358 acyl-CoA carboxylase alpha chain YP_008736992.1 6179367 D 1246995 CDS YP_008736993.1 556568568 17446343 6181291..6181884 1 NC_022657.1 COG1309 Transcriptional regulator; TetR family transcriptional regulator 6181884 17446343 AFR_28395 Actinoplanes friuliensis DSM 7358 TetR family transcriptional regulator YP_008736993.1 6181291 D 1246995 CDS YP_008736994.1 556568569 17446344 6181915..6182205 1 NC_022657.1 hypothetical protein 6182205 17446344 AFR_28400 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736994.1 6181915 D 1246995 CDS YP_008736995.1 556568570 17446345 complement(6182213..6182665) 1 NC_022657.1 hypothetical protein 6182665 17446345 AFR_28405 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736995.1 6182213 R 1246995 CDS YP_008736996.1 556568571 17446346 complement(6182670..6183149) 1 NC_022657.1 hypothetical protein 6183149 17446346 AFR_28410 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736996.1 6182670 R 1246995 CDS YP_008736997.1 556568572 17446347 6183294..6184139 1 NC_022657.1 COG2220 Predicted Zn-dependent hydrolases of the beta-lactamase fold; metal-dependent hydrolase 6184139 17446347 AFR_28415 Actinoplanes friuliensis DSM 7358 metal-dependent hydrolase YP_008736997.1 6183294 D 1246995 CDS YP_008736998.1 556568573 17446348 complement(6184121..6184417) 1 NC_022657.1 hypothetical protein 6184417 17446348 AFR_28420 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736998.1 6184121 R 1246995 CDS YP_008736999.1 556568574 17446349 6184572..6185108 1 NC_022657.1 COG5502 Uncharacterized conserved protein; hypothetical protein 6185108 17446349 AFR_28425 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008736999.1 6184572 D 1246995 CDS YP_008737000.1 556568575 17446350 complement(6185120..6186565) 1 NC_022657.1 COG3119 Arylsulfatase A and related enzymes; putative sulfatase 6186565 17446350 AFR_28430 Actinoplanes friuliensis DSM 7358 putative sulfatase YP_008737000.1 6185120 R 1246995 CDS YP_008737001.1 556568576 17446351 complement(6186659..6187048) 1 NC_022657.1 hypothetical protein 6187048 17446351 AFR_28435 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737001.1 6186659 R 1246995 CDS YP_008737002.1 556568577 17446352 6187097..6187504 1 NC_022657.1 hypothetical protein 6187504 17446352 AFR_28440 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737002.1 6187097 D 1246995 CDS YP_008737003.1 556568578 17446353 complement(6187487..6189169) 1 NC_022657.1 COG2936 Predicted acyl esterases; peptidase S15 6189169 17446353 AFR_28445 Actinoplanes friuliensis DSM 7358 peptidase S15 YP_008737003.1 6187487 R 1246995 CDS YP_008737004.1 556568579 17446354 6189321..6192092 1 NC_022657.1 COG1501 Alpha-glucosidases, family 31 of glycosyl hydrolases; putative glycosyl hydrolase 6192092 17446354 AFR_28450 Actinoplanes friuliensis DSM 7358 putative glycosyl hydrolase YP_008737004.1 6189321 D 1246995 CDS YP_008737005.1 556568580 17446355 complement(6192159..6192620) 1 NC_022657.1 COG0192 S-adenosylmethionine synthetase; hypothetical protein 6192620 17446355 AFR_28455 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737005.1 6192159 R 1246995 CDS YP_008737006.1 556568581 17446356 complement(6192680..6193075) 1 NC_022657.1 COG0126 3-phosphoglycerate kinase; hypothetical protein 6193075 17446356 AFR_28460 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737006.1 6192680 R 1246995 CDS YP_008737007.1 556568582 17446357 6193154..6193495 1 NC_022657.1 hypothetical protein 6193495 17446357 AFR_28465 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737007.1 6193154 D 1246995 CDS YP_008737008.1 556568583 17446358 complement(6193480..6193872) 1 NC_022657.1 hypothetical protein 6193872 17446358 AFR_28470 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737008.1 6193480 R 1246995 CDS YP_008737009.1 556568584 17446359 complement(6193947..6194912) 1 NC_022657.1 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; RNA polymerase factor sigma-70 6194912 17446359 AFR_28475 Actinoplanes friuliensis DSM 7358 RNA polymerase factor sigma-70 YP_008737009.1 6193947 R 1246995 CDS YP_008737010.1 556568585 17446360 complement(6194922..6199616) 1 NC_022657.1 COG0515 Serine/threonine protein kinase; serine/threonine protein kinase 6199616 17446360 AFR_28480 Actinoplanes friuliensis DSM 7358 serine/threonine protein kinase YP_008737010.1 6194922 R 1246995 CDS YP_008737011.1 556568586 17446361 complement(6199700..6201907) 1 NC_022657.1 Glycosyl hydrolase family 98 putative carbohydrate binding module 6201907 17446361 AFR_28485 Actinoplanes friuliensis DSM 7358 Glycosyl hydrolase family 98 putative carbohydrate binding module YP_008737011.1 6199700 R 1246995 CDS YP_008737012.1 556568587 17446362 complement(6201928..6204000) 1 NC_022657.1 COG3979 Uncharacterized protein contain chitin-binding domain type 3; glucose/sorbosone dehydrogenase 6204000 17446362 AFR_28490 Actinoplanes friuliensis DSM 7358 glucose/sorbosone dehydrogenase YP_008737012.1 6201928 R 1246995 CDS YP_008737013.1 556568588 17446363 6204169..6204627 1 NC_022657.1 hypothetical protein 6204627 17446363 AFR_28495 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737013.1 6204169 D 1246995 CDS YP_008737014.1 556568589 17446364 complement(6204641..6205720) 1 NC_022657.1 COG0642 Signal transduction histidine kinase; putative two-component system sensor kinase 6205720 17446364 AFR_28500 Actinoplanes friuliensis DSM 7358 putative two-component system sensor kinase YP_008737014.1 6204641 R 1246995 CDS YP_008737015.1 556568590 17446365 complement(6205750..6206409) 1 NC_022657.1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; putative transcriptional regulator ycf27 6206409 17446365 AFR_28505 Actinoplanes friuliensis DSM 7358 putative transcriptional regulator ycf27 YP_008737015.1 6205750 R 1246995 CDS YP_008737016.1 556568591 17446366 6206554..6207435 1 NC_022657.1 COG5640 Secreted trypsin-like serine protease; putative trypsin-like serine protease 6207435 17446366 AFR_28510 Actinoplanes friuliensis DSM 7358 putative trypsin-like serine protease YP_008737016.1 6206554 D 1246995 CDS YP_008737017.1 556568592 17446367 6207478..6207822 1 NC_022657.1 COG0640 Predicted transcriptional regulators; transcription regulator ArsR 6207822 17446367 AFR_28515 Actinoplanes friuliensis DSM 7358 transcription regulator ArsR YP_008737017.1 6207478 D 1246995 CDS YP_008737018.1 556568593 17446368 6207819..6208307 1 NC_022657.1 COG3832 Uncharacterized conserved protein; Hsp90 ATPase activator family protein 6208307 17446368 AFR_28520 Actinoplanes friuliensis DSM 7358 Hsp90 ATPase activator family protein YP_008737018.1 6207819 D 1246995 CDS YP_008737019.1 556568594 17446369 6208304..6208870 1 NC_022657.1 COG0262 Dihydrofolate reductase; dihydrofolate reductase 6208870 17446369 AFR_28525 Actinoplanes friuliensis DSM 7358 dihydrofolate reductase YP_008737019.1 6208304 D 1246995 CDS YP_008737020.1 556568595 17446370 6208965..6209621 1 NC_022657.1 COG0778 Nitroreductase; 5,6-dimethylbenzimidazole biosynthesis protein BluB 6209621 17446370 AFR_28530 Actinoplanes friuliensis DSM 7358 5,6-dimethylbenzimidazole biosynthesis protein BluB YP_008737020.1 6208965 D 1246995 CDS YP_008737021.1 556568596 17446371 complement(6209762..6210346) 1 NC_022657.1 COG1305 Transglutaminase-like enzymes, putative cysteine proteases; hypothetical protein 6210346 17446371 AFR_28535 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737021.1 6209762 R 1246995 CDS YP_008737022.1 556568597 17446372 complement(6210494..6211408) 1 NC_022657.1 COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases; molecular chaperone GroES 6211408 17446372 AFR_28540 Actinoplanes friuliensis DSM 7358 molecular chaperone GroES YP_008737022.1 6210494 R 1246995 CDS YP_008737023.1 556568598 17446373 complement(6211405..6211866) 1 NC_022657.1 COG1917 Uncharacterized conserved protein, contains double-stranded beta-helix domain; cupin 6211866 17446373 AFR_28545 Actinoplanes friuliensis DSM 7358 cupin YP_008737023.1 6211405 R 1246995 CDS YP_008737024.1 556568599 17446374 complement(6211881..6212834) 1 NC_022657.1 COG2207 AraC-type DNA-binding domain-containing proteins; transcriptional regulatory protein 6212834 17446374 AFR_28550 Actinoplanes friuliensis DSM 7358 transcriptional regulatory protein YP_008737024.1 6211881 R 1246995 CDS YP_008737025.1 556568600 17446375 6212940..6213644 1 NC_022657.1 hypothetical protein 6213644 17446375 AFR_28555 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737025.1 6212940 D 1246995 CDS YP_008737026.1 556568601 17446376 complement(6213660..6214133) 1 NC_022657.1 putative SnoaL-like polyketide cyclase 6214133 17446376 AFR_28560 Actinoplanes friuliensis DSM 7358 putative SnoaL-like polyketide cyclase YP_008737026.1 6213660 R 1246995 CDS YP_008737027.1 556568602 17446377 6214228..6214863 1 NC_022657.1 COG1309 Transcriptional regulator; putative TetR-family transcriptional regulator 6214863 17446377 AFR_28565 Actinoplanes friuliensis DSM 7358 putative TetR-family transcriptional regulator YP_008737027.1 6214228 D 1246995 CDS YP_008737028.1 556568603 17446378 complement(6214880..6216049) 1 NC_022657.1 COG1793 ATP-dependent DNA ligase; DNA polymerase LigD ligase domain-containing protein 6216049 17446378 AFR_28570 Actinoplanes friuliensis DSM 7358 DNA polymerase LigD ligase domain-containing protein YP_008737028.1 6214880 R 1246995 CDS YP_008737029.1 556568604 17446379 complement(6216292..6216921) 1 NC_022657.1 COG1309 Transcriptional regulator; putative TetR family transcriptional regulator 6216921 17446379 AFR_28575 Actinoplanes friuliensis DSM 7358 putative TetR family transcriptional regulator YP_008737029.1 6216292 R 1246995 CDS YP_008737030.1 556568605 17446380 6216971..6217849 1 NC_022657.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); hypothetical protein 6217849 17446380 AFR_28580 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737030.1 6216971 D 1246995 CDS YP_008737031.1 556568606 17446381 complement(6217895..6219154) 1 NC_022657.1 COG2208 Serine phosphatase RsbU, regulator of sigma subunit; protein serine/threonine phosphatase 6219154 17446381 AFR_28585 Actinoplanes friuliensis DSM 7358 protein serine/threonine phosphatase YP_008737031.1 6217895 R 1246995 CDS YP_008737032.1 556568607 17446382 complement(6219222..6219776) 1 NC_022657.1 hypothetical protein 6219776 17446382 AFR_28590 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737032.1 6219222 R 1246995 CDS YP_008737033.1 556568608 17446383 complement(6219794..6220963) 1 NC_022657.1 COG0577 ABC-type antimicrobial peptide transport system, permease component; ABC transporter permease 6220963 17446383 AFR_28595 Actinoplanes friuliensis DSM 7358 ABC transporter permease YP_008737033.1 6219794 R 1246995 CDS YP_008737034.1 556568609 17446384 complement(6220960..6221640) 1 NC_022657.1 COG1136 ABC-type antimicrobial peptide transport system, ATPase component; ABC transporter ATP-binding protein 6221640 17446384 AFR_28600 Actinoplanes friuliensis DSM 7358 ABC transporter ATP-binding protein YP_008737034.1 6220960 R 1246995 CDS YP_008737035.1 556568610 17446385 complement(6221637..6222698) 1 NC_022657.1 hypothetical protein 6222698 17446385 AFR_28605 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737035.1 6221637 R 1246995 CDS YP_008737036.1 556568611 17446386 6222815..6223492 1 NC_022657.1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; putative two-component system response regulator 6223492 17446386 AFR_28610 Actinoplanes friuliensis DSM 7358 putative two-component system response regulator YP_008737036.1 6222815 D 1246995 CDS YP_008737037.1 556568612 17446387 6223489..6225237 1 NC_022657.1 COG0642 Signal transduction histidine kinase; two-component system histidine kinase 6225237 17446387 AFR_28615 Actinoplanes friuliensis DSM 7358 two-component system histidine kinase YP_008737037.1 6223489 D 1246995 CDS YP_008737038.1 556568613 17446388 complement(6225263..6226315) 1 NC_022657.1 COG0642 Signal transduction histidine kinase; integral membrane sensor signal transduction histidine kinase 6226315 17446388 AFR_28620 Actinoplanes friuliensis DSM 7358 integral membrane sensor signal transduction histidine kinase YP_008737038.1 6225263 R 1246995 CDS YP_008737039.1 556568614 17446389 complement(6226344..6227006) 1 NC_022657.1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; response regulator receiver 6227006 17446389 AFR_28625 Actinoplanes friuliensis DSM 7358 response regulator receiver YP_008737039.1 6226344 R 1246995 CDS YP_008737040.1 556568615 17446390 complement(6227069..6228277) 1 NC_022657.1 COG5542 Predicted integral membrane protein; hypothetical protein 6228277 17446390 AFR_28630 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737040.1 6227069 R 1246995 CDS YP_008737041.1 556568616 17446391 complement(6228274..6229248) 1 NC_022657.1 COG0463 Glycosyltransferases involved in cell wall biogenesis; putative glycosyltransferase 6229248 17446391 AFR_28635 Actinoplanes friuliensis DSM 7358 putative glycosyltransferase YP_008737041.1 6228274 R 1246995 CDS YP_008737042.1 556568617 17446392 6229615..6230121 1 NC_022657.1 hypothetical protein 6230121 17446392 AFR_28640 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737042.1 6229615 D 1246995 CDS YP_008737043.1 556568618 17446393 6230239..6230532 1 NC_022657.1 hypothetical protein 6230532 17446393 AFR_28645 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737043.1 6230239 D 1246995 CDS YP_008737044.1 556568619 17446394 complement(6230559..6230807) 1 NC_022657.1 hypothetical protein 6230807 17446394 AFR_28650 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737044.1 6230559 R 1246995 CDS YP_008737045.1 556568620 17446395 complement(6230885..6231280) 1 NC_022657.1 hypothetical protein 6231280 17446395 AFR_28655 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737045.1 6230885 R 1246995 CDS YP_008737046.1 556568621 17446396 complement(6231342..6232256) 1 NC_022657.1 COG0346 Lactoylglutathione lyase and related lyases; catechol 2,3 dioxygenase 6232256 17446396 AFR_28660 Actinoplanes friuliensis DSM 7358 catechol 2,3 dioxygenase YP_008737046.1 6231342 R 1246995 CDS YP_008737047.1 556568622 17446397 complement(6232264..6232599) 1 NC_022657.1 COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases; ferredoxin 6232599 17446397 AFR_28665 Actinoplanes friuliensis DSM 7358 ferredoxin YP_008737047.1 6232264 R 1246995 CDS YP_008737048.1 556568623 17446398 6232713..6233567 1 NC_022657.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); alpha/beta-fold C-C bond hydrolase 6233567 17446398 AFR_28670 Actinoplanes friuliensis DSM 7358 alpha/beta-fold C-C bond hydrolase YP_008737048.1 6232713 D 1246995 CDS YP_008737049.1 556568624 17446399 6233624..6234340 1 NC_022657.1 COG2186 Transcriptional regulators; GntR family transcriptional regulator 6234340 17446399 AFR_28675 Actinoplanes friuliensis DSM 7358 GntR family transcriptional regulator YP_008737049.1 6233624 D 1246995 CDS YP_008737050.1 556568625 17446400 complement(6234389..6236317) 1 NC_022657.1 Mov34/MPN/PAD-1 family protein 6236317 17446400 AFR_28680 Actinoplanes friuliensis DSM 7358 Mov34/MPN/PAD-1 family protein YP_008737050.1 6234389 R 1246995 CDS YP_008737051.1 556568626 17446401 complement(6236304..6236672) 1 NC_022657.1 hypothetical protein 6236672 17446401 AFR_28685 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737051.1 6236304 R 1246995 CDS YP_008737052.1 556568627 17446402 complement(6236838..6238124) 1 NC_022657.1 hypothetical protein 6238124 17446402 AFR_28690 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737052.1 6236838 R 1246995 CDS YP_008737053.1 556568628 17446403 complement(6238205..6238450) 1 NC_022657.1 COG1408 Predicted phosphohydrolases; putative integral membrane protein 6238450 17446403 AFR_28695 Actinoplanes friuliensis DSM 7358 putative integral membrane protein YP_008737053.1 6238205 R 1246995 CDS YP_008737054.1 556568629 17446404 complement(6238469..6238846) 1 NC_022657.1 Anti-sigma F factor 6238846 17446404 AFR_28700 Actinoplanes friuliensis DSM 7358 Anti-sigma F factor YP_008737054.1 6238469 R 1246995 CDS YP_008737055.1 556568630 17446405 complement(6239130..6242207) 1 NC_022657.1 COG2202 FOG: PAS/PAC domain; PAS/PAC sensor hybrid histidine kinase 6242207 17446405 AFR_28705 Actinoplanes friuliensis DSM 7358 PAS/PAC sensor hybrid histidine kinase YP_008737055.1 6239130 R 1246995 CDS YP_008737056.1 556568631 17446406 complement(6242303..6243358) 1 NC_022657.1 COG1408 Predicted phosphohydrolases; hypothetical protein 6243358 17446406 AFR_28710 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737056.1 6242303 R 1246995 CDS YP_008737057.1 556568632 17446407 complement(6243636..6244475) 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); short-chain dehydrogenase/reductase SDR 6244475 17446407 AFR_28715 Actinoplanes friuliensis DSM 7358 short-chain dehydrogenase/reductase SDR YP_008737057.1 6243636 R 1246995 CDS YP_008737058.1 556568633 17446408 6244624..6245499 1 NC_022657.1 COG1396 Predicted transcriptional regulators; XRE family transcriptional regulator 6245499 17446408 AFR_28720 Actinoplanes friuliensis DSM 7358 XRE family transcriptional regulator YP_008737058.1 6244624 D 1246995 CDS YP_008737059.1 556568634 17446409 complement(6245530..6245832) 1 NC_022657.1 COG1846 Transcriptional regulators; putative MarR-family transcriptional regulator 6245832 17446409 AFR_28725 Actinoplanes friuliensis DSM 7358 putative MarR-family transcriptional regulator YP_008737059.1 6245530 R 1246995 CDS YP_008737060.1 556568635 17446410 complement(6245829..6246263) 1 NC_022657.1 hypothetical protein 6246263 17446410 AFR_28730 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737060.1 6245829 R 1246995 CDS YP_008737061.1 556568636 17446411 6246360..6246899 1 NC_022657.1 hypothetical protein 6246899 17446411 AFR_28735 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737061.1 6246360 D 1246995 CDS YP_008737062.1 556568637 17446412 6246896..6247357 1 NC_022657.1 hypothetical protein 6247357 17446412 AFR_28740 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737062.1 6246896 D 1246995 CDS YP_008737063.1 556568638 17446413 6247379..6248527 1 NC_022657.1 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases; putative alcohol dehydrogenase 6248527 17446413 AFR_28745 Actinoplanes friuliensis DSM 7358 putative alcohol dehydrogenase YP_008737063.1 6247379 D 1246995 CDS YP_008737064.1 556568639 17446414 6248538..6249131 1 NC_022657.1 hypothetical protein 6249131 17446414 AFR_28750 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737064.1 6248538 D 1246995 CDS YP_008737065.1 556568640 17446415 6249143..6249376 1 NC_022657.1 hypothetical protein 6249376 17446415 AFR_28755 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737065.1 6249143 D 1246995 CDS YP_008737066.1 556568641 17446416 6249463..6250878 1 NC_022657.1 COG0477 Permeases of the major facilitator superfamily; sugar transporter 6250878 17446416 AFR_28760 Actinoplanes friuliensis DSM 7358 sugar transporter YP_008737066.1 6249463 D 1246995 CDS YP_008737067.1 556568642 17446417 complement(6250850..6251947) 1 NC_022657.1 COG1835 Predicted acyltransferases; Putative peptidoglycan O-acetyltransferase yrhL 6251947 17446417 AFR_28765 Actinoplanes friuliensis DSM 7358 Putative peptidoglycan O-acetyltransferase yrhL YP_008737067.1 6250850 R 1246995 CDS YP_008737068.1 556568643 17446418 complement(6252011..6252673) 1 NC_022657.1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; LuxR family transcriptional regulator 6252673 17446418 AFR_28770 Actinoplanes friuliensis DSM 7358 LuxR family transcriptional regulator YP_008737068.1 6252011 R 1246995 CDS YP_008737069.1 556568644 17446419 complement(6252670..6253839) 1 NC_022657.1 COG4585 Signal transduction histidine kinase; histidine kinase, dimerization and phosphoacceptor region 6253839 17446419 AFR_28775 Actinoplanes friuliensis DSM 7358 histidine kinase, dimerization and phosphoacceptor region YP_008737069.1 6252670 R 1246995 CDS YP_008737070.1 556568645 17446420 6254095..6255483 1 NC_022657.1 COG0515 Serine/threonine protein kinase; serine/threonine protein kinase 6255483 17446420 AFR_28780 Actinoplanes friuliensis DSM 7358 serine/threonine protein kinase YP_008737070.1 6254095 D 1246995 CDS YP_008737071.1 556568646 17446421 6255593..6255817 1 NC_022657.1 hypothetical protein 6255817 17446421 AFR_28785 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737071.1 6255593 D 1246995 CDS YP_008737072.1 556568647 17446422 6255962..6256306 1 NC_022657.1 hypothetical protein 6256306 17446422 AFR_28790 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737072.1 6255962 D 1246995 CDS YP_008737073.1 556568648 17446423 complement(6256316..6256771) 1 NC_022657.1 hypothetical protein 6256771 17446423 AFR_28795 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737073.1 6256316 R 1246995 CDS YP_008737074.1 556568649 17446424 6256858..6257313 1 NC_022657.1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; putative response regulator 6257313 17446424 AFR_28800 Actinoplanes friuliensis DSM 7358 putative response regulator YP_008737074.1 6256858 D 1246995 CDS YP_008737075.1 556568650 17446425 6257489..6258862 1 NC_022657.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); TAP domain protein 6258862 17446425 AFR_28805 Actinoplanes friuliensis DSM 7358 TAP domain protein YP_008737075.1 6257489 D 1246995 CDS YP_008737076.1 556568651 17446426 6258850..6259509 1 NC_022657.1 hypothetical protein 6259509 17446426 AFR_28810 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737076.1 6258850 D 1246995 CDS YP_008737077.1 556568652 17446427 6259618..6260499 1 NC_022657.1 COG1131 ABC-type multidrug transport system, ATPase component; ABC transporter ATP-binding protein 6260499 17446427 AFR_28815 Actinoplanes friuliensis DSM 7358 ABC transporter ATP-binding protein YP_008737077.1 6259618 D 1246995 CDS YP_008737078.1 556568653 17446428 6260496..6261245 1 NC_022657.1 ABC transporter permease 6261245 17446428 AFR_28820 Actinoplanes friuliensis DSM 7358 ABC transporter permease YP_008737078.1 6260496 D 1246995 CDS YP_008737079.1 556568654 17446429 6261246..6262415 1 NC_022657.1 COG4585 Signal transduction histidine kinase; putative two-component sensor 6262415 17446429 AFR_28825 Actinoplanes friuliensis DSM 7358 putative two-component sensor YP_008737079.1 6261246 D 1246995 CDS YP_008737080.1 556568655 17446430 6262412..6263068 1 NC_022657.1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; two-component regulator 6263068 17446430 AFR_28830 Actinoplanes friuliensis DSM 7358 two-component regulator YP_008737080.1 6262412 D 1246995 CDS YP_008737081.1 556568656 17446431 6263107..6263484 1 NC_022657.1 COG0789 Predicted transcriptional regulators; MerR family transcriptional regulator 6263484 17446431 AFR_28835 Actinoplanes friuliensis DSM 7358 MerR family transcriptional regulator YP_008737081.1 6263107 D 1246995 CDS YP_008737082.1 556568657 17446432 complement(6263479..6264678) 1 NC_022657.1 COG4292 Predicted membrane protein; hypothetical protein 6264678 17446432 AFR_28840 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737082.1 6263479 R 1246995 CDS YP_008737083.1 556568658 17446433 complement(6264697..6265401) 1 NC_022657.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); hypothetical protein 6265401 17446433 AFR_28845 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737083.1 6264697 R 1246995 CDS YP_008737084.1 556568659 17446434 complement(6265497..6265961) 1 NC_022657.1 COG1846 Transcriptional regulators; MarR family transcriptional regulator 6265961 17446434 AFR_28850 Actinoplanes friuliensis DSM 7358 MarR family transcriptional regulator YP_008737084.1 6265497 R 1246995 CDS YP_008737085.1 556568660 17446435 complement(6265978..6266373) 1 NC_022657.1 COG4922 Uncharacterized protein conserved in bacteria; integron gene cassette protein 6266373 17446435 AFR_28855 Actinoplanes friuliensis DSM 7358 integron gene cassette protein YP_008737085.1 6265978 R 1246995 CDS YP_008737086.1 556568661 17446436 complement(6266376..6266687) 1 NC_022657.1 hypothetical protein 6266687 17446436 AFR_28860 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737086.1 6266376 R 1246995 CDS YP_008737087.1 556568662 17446437 complement(6266789..6268384) 1 NC_022657.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); exported protease 6268384 17446437 AFR_28865 Actinoplanes friuliensis DSM 7358 exported protease YP_008737087.1 6266789 R 1246995 CDS YP_008737088.1 556568663 17446438 6268569..6269471 1 NC_022657.1 COG1131 ABC-type multidrug transport system, ATPase component; ABC transporter 6269471 17446438 AFR_28870 Actinoplanes friuliensis DSM 7358 ABC transporter YP_008737088.1 6268569 D 1246995 CDS YP_008737089.1 556568664 17446439 6269482..6270201 1 NC_022657.1 ABC transporter membrane protein 6270201 17446439 AFR_28875 Actinoplanes friuliensis DSM 7358 ABC transporter membrane protein YP_008737089.1 6269482 D 1246995 CDS YP_008737090.1 556568665 17446440 6270198..6271193 1 NC_022657.1 COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases; alcohol dehydrogenase 6271193 17446440 AFR_28880 Actinoplanes friuliensis DSM 7358 alcohol dehydrogenase YP_008737090.1 6270198 D 1246995 CDS YP_008737091.1 556568666 17446441 6271216..6271524 1 NC_022657.1 COG2388 Predicted acetyltransferase; hypothetical protein 6271524 17446441 AFR_28885 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737091.1 6271216 D 1246995 CDS YP_008737092.1 556568667 17446442 complement(6271567..6272475) 1 NC_022657.1 COG1073 Hydrolases of the alpha/beta superfamily; dienelactone hydrolase domain-containing protein 6272475 17446442 AFR_28890 Actinoplanes friuliensis DSM 7358 dienelactone hydrolase domain-containing protein YP_008737092.1 6271567 R 1246995 CDS YP_008737093.1 556568668 17446443 6272574..6273020 1 NC_022657.1 COG1846 Transcriptional regulators; regulatory protein MarR 6273020 17446443 AFR_28895 Actinoplanes friuliensis DSM 7358 regulatory protein MarR YP_008737093.1 6272574 D 1246995 CDS YP_008737094.1 556568669 17446444 6272992..6273750 1 NC_022657.1 COG0789 Predicted transcriptional regulators; MerR family transcriptional regulator 6273750 17446444 AFR_28900 Actinoplanes friuliensis DSM 7358 MerR family transcriptional regulator YP_008737094.1 6272992 D 1246995 CDS YP_008737095.1 556568670 17446445 complement(6273760..6274527) 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); 3-oxoacyl-ACP reductase 6274527 17446445 AFR_28905 Actinoplanes friuliensis DSM 7358 3-oxoacyl-ACP reductase YP_008737095.1 6273760 R 1246995 CDS YP_008737096.1 556568671 17446446 6274650..6275240 1 NC_022657.1 COG1309 Transcriptional regulator; Transcriptional regulator, TetR family protein 6275240 17446446 AFR_28910 Actinoplanes friuliensis DSM 7358 Transcriptional regulator, TetR family protein YP_008737096.1 6274650 D 1246995 CDS YP_008737097.1 556568672 17446447 6275329..6276273 1 NC_022657.1 hypothetical protein 6276273 17446447 AFR_28915 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737097.1 6275329 D 1246995 CDS YP_008737098.1 556568673 17446448 complement(6276250..6278982) 1 NC_022657.1 COG3899 Predicted ATPase; LuxR family transcriptional regulator 6278982 17446448 AFR_28920 Actinoplanes friuliensis DSM 7358 LuxR family transcriptional regulator YP_008737098.1 6276250 R 1246995 CDS YP_008737099.1 556568674 17446449 complement(6279090..6279323) 1 NC_022657.1 hypothetical protein 6279323 17446449 AFR_28925 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737099.1 6279090 R 1246995 CDS YP_008737100.1 556568675 17446450 6279399..6279767 1 NC_022657.1 COG0384 Predicted epimerase, PhzC/PhzF homolog; hypothetical protein 6279767 17446450 AFR_28930 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737100.1 6279399 D 1246995 CDS YP_008737101.1 556568676 17446451 complement(6279636..6280661) 1 NC_022657.1 COG1266 Predicted metal-dependent membrane protease; CAAX amino terminal protease family protein 6280661 17446451 AFR_28935 Actinoplanes friuliensis DSM 7358 CAAX amino terminal protease family protein YP_008737101.1 6279636 R 1246995 CDS YP_008737102.1 556568677 17446452 complement(6280658..6282112) 1 NC_022657.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); TAP domain-containing protein 6282112 17446452 AFR_28940 Actinoplanes friuliensis DSM 7358 TAP domain-containing protein YP_008737102.1 6280658 R 1246995 CDS YP_008737103.1 556568678 17446453 complement(6282194..6282631) 1 NC_022657.1 hypothetical protein 6282631 17446453 AFR_28945 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737103.1 6282194 R 1246995 CDS YP_008737104.1 556568679 17446454 6283025..6285535 1 NC_022657.1 COG2203 FOG: GAF domain; putative GAF-sensor signal transduction histidine kinase 6285535 17446454 AFR_28950 Actinoplanes friuliensis DSM 7358 putative GAF-sensor signal transduction histidine kinase YP_008737104.1 6283025 D 1246995 CDS YP_008737105.1 556568680 17446455 complement(6285501..6287642) 1 NC_022657.1 COG2203 FOG: GAF domain; GAF sensor signal transduction histidine kinase 6287642 17446455 AFR_28955 Actinoplanes friuliensis DSM 7358 GAF sensor signal transduction histidine kinase YP_008737105.1 6285501 R 1246995 CDS YP_008737106.1 556568681 17446456 complement(6287652..6288338) 1 NC_022657.1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; LuxR family transcriptional regulator 6288338 17446456 AFR_28960 Actinoplanes friuliensis DSM 7358 LuxR family transcriptional regulator YP_008737106.1 6287652 R 1246995 CDS YP_008737107.1 556568682 17446457 complement(6288325..6288699) 1 NC_022657.1 COG0784 FOG: CheY-like receiver; response regulator receiver protein 6288699 17446457 AFR_28965 Actinoplanes friuliensis DSM 7358 response regulator receiver protein YP_008737107.1 6288325 R 1246995 CDS YP_008737108.1 556568683 17446458 6288873..6289718 1 NC_022657.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); hydrolase 6289718 17446458 AFR_28970 Actinoplanes friuliensis DSM 7358 hydrolase YP_008737108.1 6288873 D 1246995 CDS YP_008737109.1 556568684 17446459 6289730..6290638 1 NC_022657.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); haloacetate dehalogenase 6290638 17446459 AFR_28975 Actinoplanes friuliensis DSM 7358 haloacetate dehalogenase YP_008737109.1 6289730 D 1246995 CDS YP_008737110.1 556568685 17446460 6290654..6291013 1 NC_022657.1 COG1917 Uncharacterized conserved protein, contains double-stranded beta-helix domain; hypothetical protein 6291013 17446460 AFR_28980 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737110.1 6290654 D 1246995 CDS YP_008737111.1 556568686 17446461 6291036..6291770 1 NC_022657.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); hypothetical protein 6291770 17446461 AFR_28985 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737111.1 6291036 D 1246995 CDS YP_008737112.1 556568687 17446462 6291767..6292735 1 NC_022657.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); chloroperoxidase 6292735 17446462 AFR_28990 Actinoplanes friuliensis DSM 7358 chloroperoxidase YP_008737112.1 6291767 D 1246995 CDS YP_008737113.1 556568688 17446463 6292934..6293746 1 NC_022657.1 COG1275 Tellurite resistance protein and related permeases; potassium-tellurite ethidium and proflavin transporter 6293746 17446463 AFR_28995 Actinoplanes friuliensis DSM 7358 potassium-tellurite ethidium and proflavin transporter YP_008737113.1 6292934 D 1246995 CDS YP_008737114.1 556568689 17446464 complement(6293756..6294679) 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); short-chain dehydrogenase/reductase SDR 6294679 17446464 AFR_29000 Actinoplanes friuliensis DSM 7358 short-chain dehydrogenase/reductase SDR YP_008737114.1 6293756 R 1246995 CDS YP_008737115.1 556568690 17446465 6294866..6295669 1 NC_022657.1 COG0500 SAM-dependent methyltransferases; SAM dependent methyltransferase 6295669 17446465 AFR_29005 Actinoplanes friuliensis DSM 7358 SAM dependent methyltransferase YP_008737115.1 6294866 D 1246995 CDS YP_008737116.1 556568691 17446466 complement(6295676..6296545) 1 NC_022657.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); alpha/beta hydrolase fold protein 6296545 17446466 AFR_29010 Actinoplanes friuliensis DSM 7358 alpha/beta hydrolase fold protein YP_008737116.1 6295676 R 1246995 CDS YP_008737117.1 556568692 17446467 6296636..6297109 1 NC_022657.1 COG1846 Transcriptional regulators; regulatory protein MarR 6297109 17446467 AFR_29015 Actinoplanes friuliensis DSM 7358 regulatory protein MarR YP_008737117.1 6296636 D 1246995 CDS YP_008737118.1 556568693 17446468 complement(6297114..6298022) 1 NC_022657.1 COG1295 Predicted membrane protein; hypothetical protein 6298022 17446468 AFR_29020 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737118.1 6297114 R 1246995 CDS YP_008737119.1 556568694 17446469 complement(6298089..6298496) 1 NC_022657.1 COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase; glycosyl transferase family protein 6298496 17446469 AFR_29025 Actinoplanes friuliensis DSM 7358 glycosyl transferase family protein YP_008737119.1 6298089 R 1246995 CDS YP_008737120.1 556568695 17446470 6298530..6299483 1 NC_022657.1 COG0457 FOG: TPR repeat; putative AfsR family transcriptional regulator 6299483 17446470 AFR_29030 Actinoplanes friuliensis DSM 7358 putative AfsR family transcriptional regulator YP_008737120.1 6298530 D 1246995 CDS YP_008737121.1 556568696 17446471 complement(6299452..6299970) 1 NC_022657.1 COG2203 FOG: GAF domain; hypothetical protein 6299970 17446471 AFR_29035 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737121.1 6299452 R 1246995 CDS YP_008737122.1 556568697 17446472 complement(6299973..6300260) 1 NC_022657.1 hypothetical protein 6300260 17446472 AFR_29040 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737122.1 6299973 R 1246995 CDS YP_008737123.1 556568698 17446473 complement(6300291..6301925) 1 NC_022657.1 COG0840 Methyl-accepting chemotaxis protein; methyl-accepting chemotaxis protein 6301925 17446473 AFR_29045 Actinoplanes friuliensis DSM 7358 methyl-accepting chemotaxis protein YP_008737123.1 6300291 R 1246995 CDS YP_008737124.1 556568699 17446474 complement(6302094..6302723) 1 NC_022657.1 COG0586 Uncharacterized membrane-associated protein; hypothetical protein 6302723 17446474 AFR_29050 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737124.1 6302094 R 1246995 CDS YP_008737125.1 556568700 17446475 6303092..6303595 1 NC_022657.1 hypothetical protein 6303595 17446475 AFR_29055 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737125.1 6303092 D 1246995 CDS YP_008737126.1 556568701 17446476 complement(6303745..6305070) 1 NC_022657.1 hypothetical protein 6305070 17446476 AFR_29060 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737126.1 6303745 R 1246995 CDS YP_008737127.1 556568702 17446477 complement(6305142..6306794) 1 NC_022657.1 COG0515 Serine/threonine protein kinase; WD-40 repeat-containing serine/threonine protein kinase 6306794 17446477 AFR_29065 Actinoplanes friuliensis DSM 7358 WD-40 repeat-containing serine/threonine protein kinase YP_008737127.1 6305142 R 1246995 CDS YP_008737128.1 556568703 17446478 6306932..6308446 1 NC_022657.1 COG0515 Serine/threonine protein kinase; putative serine/threonine protein kinase 6308446 17446478 AFR_29070 Actinoplanes friuliensis DSM 7358 putative serine/threonine protein kinase YP_008737128.1 6306932 D 1246995 CDS YP_008737129.1 556568704 17446479 6308754..6310115 1 NC_022657.1 hypothetical protein 6310115 17446479 AFR_29075 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737129.1 6308754 D 1246995 CDS YP_008737130.1 556568705 17446480 complement(6310168..6311019) 1 NC_022657.1 COG2240 Pyridoxal/pyridoxine/pyridoxamine kinase; pyridoxamine kinase 6311019 17446480 AFR_29080 Actinoplanes friuliensis DSM 7358 pyridoxamine kinase YP_008737130.1 6310168 R 1246995 CDS YP_008737131.1 556568706 17446481 6311081..6311836 1 NC_022657.1 COG2186 Transcriptional regulators; transcriptional regulator 6311836 17446481 AFR_29085 Actinoplanes friuliensis DSM 7358 transcriptional regulator YP_008737131.1 6311081 D 1246995 CDS YP_008737132.1 556568707 17446482 complement(6311778..6312788) 1 NC_022657.1 COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases); oxidoreductase 6312788 17446482 AFR_29090 Actinoplanes friuliensis DSM 7358 oxidoreductase YP_008737132.1 6311778 R 1246995 CDS YP_008737133.1 556568708 17446483 complement(6312797..6313612) 1 NC_022657.1 COG3618 Predicted metal-dependent hydrolase of the TIM-barrel fold; amidohydrolase 6313612 17446483 AFR_29095 Actinoplanes friuliensis DSM 7358 amidohydrolase YP_008737133.1 6312797 R 1246995 CDS YP_008737134.1 556568709 17446484 complement(6313609..6313962) 1 NC_022657.1 COG3254 Uncharacterized conserved protein; hypothetical protein 6313962 17446484 AFR_29100 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737134.1 6313609 R 1246995 CDS YP_008737135.1 556568710 17446485 complement(6313947..6315134) 1 NC_022657.1 COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily; racemase 6315134 17446485 AFR_29105 Actinoplanes friuliensis DSM 7358 racemase YP_008737135.1 6313947 R 1246995 CDS YP_008737136.1 556568711 17446486 complement(6315163..6316074) 1 NC_022657.1 COG0395 ABC-type sugar transport system, permease component; ABC transporter permease 6316074 17446486 AFR_29110 Actinoplanes friuliensis DSM 7358 ABC transporter permease YP_008737136.1 6315163 R 1246995 CDS YP_008737137.1 556568712 17446487 complement(6316079..6317011) 1 NC_022657.1 COG1175 ABC-type sugar transport systems, permease components; sugar ABC transporter permease 6317011 17446487 AFR_29115 Actinoplanes friuliensis DSM 7358 sugar ABC transporter permease YP_008737137.1 6316079 R 1246995 CDS YP_008737138.1 556568713 17446488 complement(6317008..6318234) 1 NC_022657.1 COG1653 ABC-type sugar transport system, periplasmic component; extracellular solute-binding protein 6318234 17446488 AFR_29120 Actinoplanes friuliensis DSM 7358 extracellular solute-binding protein YP_008737138.1 6317008 R 1246995 CDS YP_008737139.1 556568714 17446489 6318493..6319524 1 NC_022657.1 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases; threonine dehydrogenase 6319524 17446489 AFR_29125 Actinoplanes friuliensis DSM 7358 threonine dehydrogenase YP_008737139.1 6318493 D 1246995 CDS YP_008737140.1 556568715 17446490 6319521..6320276 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); dehydrogenase with different specificities 6320276 17446490 AFR_29130 Actinoplanes friuliensis DSM 7358 dehydrogenase with different specificities YP_008737140.1 6319521 D 1246995 CDS YP_008737141.1 556568716 17446491 complement(6320285..6320647) 1 NC_022657.1 COG1733 Predicted transcriptional regulators; cinnamoyl ester hydrolase 6320647 17446491 AFR_29135 Actinoplanes friuliensis DSM 7358 cinnamoyl ester hydrolase YP_008737141.1 6320285 R 1246995 CDS YP_008737142.1 556568717 17446492 6320748..6321443 1 NC_022657.1 COG2085 Predicted dinucleotide-binding enzymes; NADP oxidoreductase coenzyme F420-dependent 6321443 17446492 AFR_29140 Actinoplanes friuliensis DSM 7358 NADP oxidoreductase coenzyme F420-dependent YP_008737142.1 6320748 D 1246995 CDS YP_008737143.1 556568718 17446493 complement(6321478..6322422) 1 NC_022657.1 COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases; zinc-containing alcohol dehydrogenase 6322422 17446493 AFR_29145 Actinoplanes friuliensis DSM 7358 zinc-containing alcohol dehydrogenase YP_008737143.1 6321478 R 1246995 CDS YP_008737144.1 556568719 17446494 complement(6322419..6323096) 1 NC_022657.1 COG2085 Predicted dinucleotide-binding enzymes; coenzyme F420-dependent NADP oxidoreductase 6323096 17446494 AFR_29150 Actinoplanes friuliensis DSM 7358 coenzyme F420-dependent NADP oxidoreductase YP_008737144.1 6322419 R 1246995 CDS YP_008737145.1 556568720 17446495 6323177..6324115 1 NC_022657.1 COG2207 AraC-type DNA-binding domain-containing proteins; AraC family transcriptional regulator 6324115 17446495 AFR_29155 Actinoplanes friuliensis DSM 7358 AraC family transcriptional regulator YP_008737145.1 6323177 D 1246995 CDS YP_008737146.1 556568721 17446496 complement(6324145..6326538) 1 NC_022657.1 galactosylceramidase 6326538 17446496 AFR_29160 Actinoplanes friuliensis DSM 7358 galactosylceramidase YP_008737146.1 6324145 R 1246995 CDS YP_008737147.1 556568722 17446497 complement(6326523..6328139) 1 NC_022657.1 COG3345 Alpha-galactosidase; ricin B lectin 6328139 17446497 AFR_29165 Actinoplanes friuliensis DSM 7358 ricin B lectin YP_008737147.1 6326523 R 1246995 CDS YP_008737148.1 556568723 17446498 complement(6328161..6329264) 1 NC_022657.1 COG2755 Lysophospholipase L1 and related esterases; putative GDSL-like lipase/acylhydrolase with Ricin-type beta-trefoil lectin domain 6329264 17446498 AFR_29170 Actinoplanes friuliensis DSM 7358 putative GDSL-like lipase/acylhydrolase with Ricin-type beta-trefoil lectin domain YP_008737148.1 6328161 R 1246995 CDS YP_008737149.1 556568724 17446499 6329519..6331849 1 NC_022657.1 COG3533 Uncharacterized protein conserved in bacteria; hypothetical protein 6331849 17446499 AFR_29175 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737149.1 6329519 D 1246995 CDS YP_008737150.1 556568725 17446500 complement(6331908..6334289) 1 NC_022657.1 xylanase A 6334289 17446500 AFR_29180 Actinoplanes friuliensis DSM 7358 xylanase A YP_008737150.1 6331908 R 1246995 CDS YP_008737151.1 556568726 17446501 complement(6334318..6336168) 1 NC_022657.1 COG3507 Beta-xylosidase; alpha-n-arabinofuranosidase 6336168 17446501 AFR_29185 Actinoplanes friuliensis DSM 7358 alpha-n-arabinofuranosidase YP_008737151.1 6334318 R 1246995 CDS YP_008737152.1 556568727 17446502 complement(6336200..6338269) 1 NC_022657.1 COG3507 Beta-xylosidase; putative glycosyl hydrolase 6338269 17446502 AFR_29190 Actinoplanes friuliensis DSM 7358 putative glycosyl hydrolase YP_008737152.1 6336200 R 1246995 CDS YP_008737153.1 556568728 17446503 complement(6338484..6339914) 1 NC_022657.1 glycosyl hydrolase 6339914 17446503 AFR_29195 Actinoplanes friuliensis DSM 7358 glycosyl hydrolase YP_008737153.1 6338484 R 1246995 CDS YP_008737154.1 556568729 17446504 6340378..6343191 1 NC_022657.1 COG2133 Glucose/sorbosone dehydrogenases; ricin b lectin 6343191 17446504 AFR_29200 Actinoplanes friuliensis DSM 7358 ricin b lectin YP_008737154.1 6340378 D 1246995 CDS YP_008737155.1 556568730 17446505 6343206..6344903 1 NC_022657.1 glycosyl hydrolase 6344903 17446505 AFR_29205 Actinoplanes friuliensis DSM 7358 glycosyl hydrolase YP_008737155.1 6343206 D 1246995 CDS YP_008737156.1 556568731 17446506 6344900..6347758 1 NC_022657.1 hypothetical protein 6347758 17446506 AFR_29210 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737156.1 6344900 D 1246995 CDS YP_008737157.1 556568732 17446507 complement(6347875..6348651) 1 NC_022657.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); alpha/beta superfamily-like protein 6348651 17446507 AFR_29215 Actinoplanes friuliensis DSM 7358 alpha/beta superfamily-like protein YP_008737157.1 6347875 R 1246995 CDS YP_008737158.1 556568733 17446508 6349241..6350995 1 NC_022657.1 COG1132 ABC-type multidrug transport system, ATPase and permease components; ABC transporter 6350995 17446508 AFR_29220 Actinoplanes friuliensis DSM 7358 ABC transporter YP_008737158.1 6349241 D 1246995 CDS YP_008737159.1 556568734 17446509 complement(6350974..6351702) 1 NC_022657.1 hypothetical protein 6351702 17446509 AFR_29225 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737159.1 6350974 R 1246995 CDS YP_008737160.1 556568735 17446510 complement(6351714..6351935) 1 NC_022657.1 COG3251 Uncharacterized protein conserved in bacteria; MbtH-like protein 6351935 17446510 AFR_29230 Actinoplanes friuliensis DSM 7358 MbtH-like protein YP_008737160.1 6351714 R 1246995 CDS YP_008737161.1 556568736 17446511 complement(6351932..6357898) 1 NC_022657.1 COG1020 Non-ribosomal peptide synthetase modules and related proteins; putative non ribosomal peptide synthetase protein 6357898 17446511 AFR_29235 Actinoplanes friuliensis DSM 7358 putative non ribosomal peptide synthetase protein YP_008737161.1 6351932 R 1246995 CDS YP_008737162.1 556568737 17446512 complement(6358223..6358978) 1 NC_022657.1 COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III; beta-lactamase domain-containing protein 6358978 17446512 AFR_29240 Actinoplanes friuliensis DSM 7358 beta-lactamase domain-containing protein YP_008737162.1 6358223 R 1246995 CDS YP_008737163.1 556568738 17446513 complement(6358999..6359559) 1 NC_022657.1 COG1309 Transcriptional regulator; hypothetical protein 6359559 17446513 AFR_29245 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737163.1 6358999 R 1246995 CDS YP_008737164.1 556568739 17446514 6359996..6360868 1 NC_022657.1 COG4188 Predicted dienelactone hydrolase; triacylglycerol lipase 6360868 17446514 AFR_29250 Actinoplanes friuliensis DSM 7358 triacylglycerol lipase YP_008737164.1 6359996 D 1246995 CDS YP_008737165.1 556568740 17446515 complement(6360900..6361244) 1 NC_022657.1 hypothetical protein 6361244 17446515 AFR_29255 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737165.1 6360900 R 1246995 CDS YP_008737166.1 556568741 17446516 complement(6361477..6362034) 1 NC_022657.1 COG0346 Lactoylglutathione lyase and related lyases; lactoylglutathione lyase 6362034 17446516 AFR_29260 Actinoplanes friuliensis DSM 7358 lactoylglutathione lyase YP_008737166.1 6361477 R 1246995 CDS YP_008737167.1 556568742 17446517 6362126..6363022 1 NC_022657.1 COG0583 Transcriptional regulator; LysR family transcriptional regulator 6363022 17446517 AFR_29265 Actinoplanes friuliensis DSM 7358 LysR family transcriptional regulator YP_008737167.1 6362126 D 1246995 CDS YP_008737168.1 556568743 17446518 complement(6363026..6363946) 1 NC_022657.1 COG0583 Transcriptional regulator; LysR family transcriptional regulator 6363946 17446518 AFR_29270 Actinoplanes friuliensis DSM 7358 LysR family transcriptional regulator YP_008737168.1 6363026 R 1246995 CDS YP_008737169.1 556568744 17446519 6364306..6365154 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); short chain dehydrogenase 6365154 17446519 AFR_29275 Actinoplanes friuliensis DSM 7358 short chain dehydrogenase YP_008737169.1 6364306 D 1246995 CDS YP_008737170.1 556568745 17446520 6365205..6366869 1 NC_022657.1 COG0281 Malic enzyme; malate dehydrogenase 6366869 17446520 AFR_29280 Actinoplanes friuliensis DSM 7358 malate dehydrogenase YP_008737170.1 6365205 D 1246995 CDS YP_008737171.1 556568746 17446521 6366873..6368378 1 NC_022657.1 COG0114 Fumarase; fumarate hydratase 6368378 fumC1 17446521 fumC1 Actinoplanes friuliensis DSM 7358 fumarate hydratase YP_008737171.1 6366873 D 1246995 CDS YP_008737172.1 556568747 17446522 6368653..6369324 1 NC_022657.1 COG0693 Putative intracellular protease/amidase; DJ-1/PfpI family transcriptional regulator 6369324 17446522 AFR_29290 Actinoplanes friuliensis DSM 7358 DJ-1/PfpI family transcriptional regulator YP_008737172.1 6368653 D 1246995 CDS YP_008737173.1 556568748 17446523 6369384..6370790 1 NC_022657.1 COG0154 Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases; amidase 6370790 17446523 AFR_29295 Actinoplanes friuliensis DSM 7358 amidase YP_008737173.1 6369384 D 1246995 CDS YP_008737174.1 556568749 17446524 6370813..6371499 1 NC_022657.1 COG0702 Predicted nucleoside-diphosphate-sugar epimerases; NAD-dependent epimerase/dehydratase 6371499 17446524 AFR_29300 Actinoplanes friuliensis DSM 7358 NAD-dependent epimerase/dehydratase YP_008737174.1 6370813 D 1246995 CDS YP_008737175.1 556568750 17446525 complement(6371485..6372186) 1 NC_022657.1 COG1309 Transcriptional regulator; TetR family transcriptional regulator 6372186 17446525 AFR_29305 Actinoplanes friuliensis DSM 7358 TetR family transcriptional regulator YP_008737175.1 6371485 R 1246995 CDS YP_008737176.1 556568751 17446526 6372464..6372868 1 NC_022657.1 hypothetical protein 6372868 17446526 AFR_29310 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737176.1 6372464 D 1246995 CDS YP_008737177.1 556568752 17446527 6372978..6373811 1 NC_022657.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); hydrolase 6373811 17446527 AFR_29315 Actinoplanes friuliensis DSM 7358 hydrolase YP_008737177.1 6372978 D 1246995 CDS YP_008737178.1 556568753 17446528 6373895..6374443 1 NC_022657.1 COG2207 AraC-type DNA-binding domain-containing proteins; AraC family transcriptional regulator 6374443 17446528 AFR_29320 Actinoplanes friuliensis DSM 7358 AraC family transcriptional regulator YP_008737178.1 6373895 D 1246995 CDS YP_008737179.1 556568754 17446529 complement(6374437..6374793) 1 NC_022657.1 COG5485 Predicted ester cyclase; hypothetical protein 6374793 17446529 AFR_29325 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737179.1 6374437 R 1246995 CDS YP_008737180.1 556568755 17446530 6375067..6376299 1 NC_022657.1 COG2807 Cyanate permease; MFS family permease 6376299 17446530 AFR_29330 Actinoplanes friuliensis DSM 7358 MFS family permease YP_008737180.1 6375067 D 1246995 CDS YP_008737181.1 556568756 17446531 6376802..6377458 1 NC_022657.1 hypothetical protein 6377458 17446531 AFR_29335 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737181.1 6376802 D 1246995 CDS YP_008737182.1 556568757 17446532 6377455..6377961 1 NC_022657.1 hypothetical protein 6377961 17446532 AFR_29340 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737182.1 6377455 D 1246995 CDS YP_008737183.1 556568758 17446533 complement(6379263..6379799) 1 NC_022657.1 COG1309 Transcriptional regulator; TetR family transcriptional regulator 6379799 17446533 AFR_29345 Actinoplanes friuliensis DSM 7358 TetR family transcriptional regulator YP_008737183.1 6379263 R 1246995 CDS YP_008737184.1 556568759 17446534 complement(6379845..6380315) 1 NC_022657.1 COG3631 Ketosteroid isomerase-related protein; putative isomerase 6380315 17446534 AFR_29350 Actinoplanes friuliensis DSM 7358 putative isomerase YP_008737184.1 6379845 R 1246995 CDS YP_008737185.1 556568760 17446535 complement(6380523..6382100) 1 NC_022657.1 COG1928 Dolichyl-phosphate-mannose--protein O-mannosyl transferase; hypothetical protein 6382100 17446535 AFR_29355 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737185.1 6380523 R 1246995 CDS YP_008737186.1 556568761 17446536 6382198..6382767 1 NC_022657.1 COG1309 Transcriptional regulator; TetR family transcriptional regulator 6382767 17446536 AFR_29360 Actinoplanes friuliensis DSM 7358 TetR family transcriptional regulator YP_008737186.1 6382198 D 1246995 CDS YP_008737187.1 556568762 17446537 complement(6382789..6383283) 1 NC_022657.1 hypothetical protein 6383283 17446537 AFR_29365 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737187.1 6382789 R 1246995 CDS YP_008737188.1 556568763 17446538 6383452..6384951 1 NC_022657.1 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases; hypothetical protein 6384951 17446538 AFR_29370 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737188.1 6383452 D 1246995 CDS YP_008737189.1 556568764 17446539 complement(6384948..6386189) 1 NC_022657.1 COG0675 Transposase and inactivated derivatives; transposase, IS605 OrfB family protein 6386189 17446539 AFR_29375 Actinoplanes friuliensis DSM 7358 transposase, IS605 OrfB family protein YP_008737189.1 6384948 R 1246995 CDS YP_008737190.1 556568765 17446540 6386303..6386425 1 NC_022657.1 COG1943 Transposase and inactivated derivatives; transposase 6386425 17446540 AFR_29380 Actinoplanes friuliensis DSM 7358 transposase YP_008737190.1 6386303 D 1246995 CDS YP_008737191.1 556568766 17446541 6386534..6387688 1 NC_022657.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); hypothetical protein 6387688 17446541 AFR_29385 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737191.1 6386534 D 1246995 CDS YP_008737192.1 556568767 17446542 6387691..6388500 1 NC_022657.1 amidohydrolase 2 6388500 17446542 AFR_29390 Actinoplanes friuliensis DSM 7358 amidohydrolase 2 YP_008737192.1 6387691 D 1246995 CDS YP_008737193.1 556568768 17446543 6388497..6389258 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); short-chain dehydrogenase/reductase SDR 6389258 17446543 AFR_29395 Actinoplanes friuliensis DSM 7358 short-chain dehydrogenase/reductase SDR YP_008737193.1 6388497 D 1246995 CDS YP_008737194.1 556568769 17446544 6389335..6389883 1 NC_022657.1 hypothetical protein 6389883 17446544 AFR_29400 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737194.1 6389335 D 1246995 CDS YP_008737195.1 556568770 17446545 complement(6389900..6391069) 1 NC_022657.1 COG0577 ABC-type antimicrobial peptide transport system, permease component; putative permease 6391069 17446545 AFR_29405 Actinoplanes friuliensis DSM 7358 putative permease YP_008737195.1 6389900 R 1246995 CDS YP_008737196.1 556568771 17446546 complement(6391084..6391755) 1 NC_022657.1 COG1136 ABC-type antimicrobial peptide transport system, ATPase component; ABC transporter ATP-binding protein 6391755 17446546 AFR_29410 Actinoplanes friuliensis DSM 7358 ABC transporter ATP-binding protein YP_008737196.1 6391084 R 1246995 CDS YP_008737197.1 556568772 17446547 complement(6391752..6392939) 1 NC_022657.1 hypothetical protein 6392939 17446547 AFR_29415 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737197.1 6391752 R 1246995 CDS YP_008737198.1 556568773 17446548 6393037..6393714 1 NC_022657.1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; putative two-component system response regulator 6393714 17446548 AFR_29420 Actinoplanes friuliensis DSM 7358 putative two-component system response regulator YP_008737198.1 6393037 D 1246995 CDS YP_008737199.1 556568774 17446549 6393714..6395507 1 NC_022657.1 COG0642 Signal transduction histidine kinase; putative two-component system sensor kinase 6395507 17446549 AFR_29425 Actinoplanes friuliensis DSM 7358 putative two-component system sensor kinase YP_008737199.1 6393714 D 1246995 CDS YP_008737200.1 556568775 17446550 6395536..6396372 1 NC_022657.1 hypothetical protein 6396372 17446550 AFR_29430 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737200.1 6395536 D 1246995 CDS YP_008737201.1 556568776 17446551 complement(6396365..6398536) 1 NC_022657.1 COG3576 Predicted flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase; Oxidoreductase FAD-binding domain-containing protein 6398536 17446551 AFR_29435 Actinoplanes friuliensis DSM 7358 Oxidoreductase FAD-binding domain-containing protein YP_008737201.1 6396365 R 1246995 CDS YP_008737202.1 556568777 17446552 6398601..6399221 1 NC_022657.1 COG1309 Transcriptional regulator; TetR family transcriptional regulator 6399221 17446552 AFR_29440 Actinoplanes friuliensis DSM 7358 TetR family transcriptional regulator YP_008737202.1 6398601 D 1246995 CDS YP_008737203.1 556568778 17446553 complement(6399301..6399795) 1 NC_022657.1 hypothetical protein 6399795 17446553 AFR_29445 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737203.1 6399301 R 1246995 CDS YP_008737204.1 556568779 17446554 complement(6399931..6401733) 1 NC_022657.1 COG3903 Predicted ATPase; regulatory protein 6401733 17446554 AFR_29450 Actinoplanes friuliensis DSM 7358 regulatory protein YP_008737204.1 6399931 R 1246995 CDS YP_008737205.1 556568780 17446555 complement(6401835..6403247) 1 NC_022657.1 COG0277 FAD/FMN-containing dehydrogenases; FAD-dependent oxygenase 6403247 17446555 AFR_29455 Actinoplanes friuliensis DSM 7358 FAD-dependent oxygenase YP_008737205.1 6401835 R 1246995 CDS YP_008737206.1 556568781 17446556 complement(6403443..6403883) 1 NC_022657.1 COG5485 Predicted ester cyclase; hypothetical protein 6403883 17446556 AFR_29460 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737206.1 6403443 R 1246995 CDS YP_008737207.1 556568782 17446557 6404072..6404500 1 NC_022657.1 COG1846 Transcriptional regulators; MarR family transcriptional regulator 6404500 17446557 AFR_29465 Actinoplanes friuliensis DSM 7358 MarR family transcriptional regulator YP_008737207.1 6404072 D 1246995 CDS YP_008737208.1 556568783 17446558 complement(6404706..6405287) 1 NC_022657.1 COG1309 Transcriptional regulator; TetR family transcriptional regulator 6405287 17446558 AFR_29470 Actinoplanes friuliensis DSM 7358 TetR family transcriptional regulator YP_008737208.1 6404706 R 1246995 CDS YP_008737209.1 556568784 17446559 6405545..6406285 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); dehydrogenase 6406285 17446559 AFR_29475 Actinoplanes friuliensis DSM 7358 dehydrogenase YP_008737209.1 6405545 D 1246995 CDS YP_008737210.1 556568785 17446560 6406324..6407322 1 NC_022657.1 COG1741 Pirin-related protein; Pirin domain-containing protein 6407322 17446560 AFR_29480 Actinoplanes friuliensis DSM 7358 Pirin domain-containing protein YP_008737210.1 6406324 D 1246995 CDS YP_008737211.1 556568786 17446561 complement(6407366..6408148) 1 NC_022657.1 hypothetical protein 6408148 17446561 AFR_29485 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737211.1 6407366 R 1246995 CDS YP_008737212.1 556568787 17446562 complement(6408292..6409866) 1 NC_022657.1 Sialidase 6409866 17446562 AFR_29490 Actinoplanes friuliensis DSM 7358 Sialidase YP_008737212.1 6408292 R 1246995 CDS YP_008737213.1 556568788 17446563 complement(6410003..6410365) 1 NC_022657.1 glyoxalase/bleomycin resistance protein/dioxygenase 6410365 17446563 AFR_29495 Actinoplanes friuliensis DSM 7358 glyoxalase/bleomycin resistance protein/dioxygenase YP_008737213.1 6410003 R 1246995 CDS YP_008737214.1 556568789 17446564 complement(6410362..6411987) 1 NC_022657.1 COG0477 Permeases of the major facilitator superfamily; transporter 6411987 17446564 AFR_29500 Actinoplanes friuliensis DSM 7358 transporter YP_008737214.1 6410362 R 1246995 CDS YP_008737215.1 556568790 17446565 complement(6411984..6412769) 1 NC_022657.1 COG0657 Esterase/lipase; hypothetical protein 6412769 17446565 AFR_29505 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737215.1 6411984 R 1246995 CDS YP_008737216.1 556568791 17446566 complement(6412927..6413358) 1 NC_022657.1 hypothetical protein 6413358 17446566 AFR_29510 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737216.1 6412927 R 1246995 CDS YP_008737217.1 556568792 17446567 complement(6414073..6414453) 1 NC_022657.1 COG0582 Integrase; hypothetical protein 6414453 17446567 AFR_29515 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737217.1 6414073 R 1246995 CDS YP_008737218.1 556568793 17446568 complement(6414508..6416238) 1 NC_022657.1 hypothetical protein 6416238 17446568 AFR_29520 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737218.1 6414508 R 1246995 CDS YP_008737219.1 556568794 17446569 complement(6416262..6419405) 1 NC_022657.1 COG0433 Predicted ATPase; AAA ATPase 6419405 17446569 AFR_29525 Actinoplanes friuliensis DSM 7358 AAA ATPase YP_008737219.1 6416262 R 1246995 CDS YP_008737220.1 556568795 17446570 complement(6419402..6419923) 1 NC_022657.1 hypothetical protein 6419923 17446570 AFR_29530 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737220.1 6419402 R 1246995 CDS YP_008737221.1 556568796 17446571 complement(6421168..6422043) 1 NC_022657.1 hypothetical protein 6422043 17446571 AFR_29535 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737221.1 6421168 R 1246995 CDS YP_008737222.1 556568797 17446572 complement(6422464..6423621) 1 NC_022657.1 hypothetical protein 6423621 17446572 AFR_29540 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737222.1 6422464 R 1246995 CDS YP_008737223.1 556568798 17446573 complement(6423749..6424138) 1 NC_022657.1 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; putative RNA polymerase ECF-subfamily sigma factor 6424138 17446573 AFR_29545 Actinoplanes friuliensis DSM 7358 putative RNA polymerase ECF-subfamily sigma factor YP_008737223.1 6423749 R 1246995 CDS YP_008737224.1 556568799 17446574 complement(6424796..6425254) 1 NC_022657.1 hypothetical protein 6425254 17446574 AFR_29550 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737224.1 6424796 R 1246995 CDS YP_008737225.1 556568800 17446575 complement(6426194..6427741) 1 NC_022657.1 COG1502 Phosphatidylserine/phosphatidylglycerophosphate/cardiolipi n synthases and related enzymes; hypothetical protein 6427741 17446575 AFR_29555 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737225.1 6426194 R 1246995 CDS YP_008737226.1 556568801 17446576 complement(6427734..6428909) 1 NC_022657.1 hypothetical protein 6428909 17446576 AFR_29560 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737226.1 6427734 R 1246995 CDS YP_008737227.1 556568802 17446577 complement(6428906..6432739) 1 NC_022657.1 COG1112 Superfamily I DNA and RNA helicases and helicase subunits; putative DNA helicase 6432739 17446577 AFR_29565 Actinoplanes friuliensis DSM 7358 putative DNA helicase YP_008737227.1 6428906 R 1246995 CDS YP_008737228.1 556568803 17446578 complement(6432793..6434226) 1 NC_022657.1 CRISPR-associated protein 6434226 17446578 AFR_29570 Actinoplanes friuliensis DSM 7358 CRISPR-associated protein YP_008737228.1 6432793 R 1246995 CDS YP_008737229.1 556568804 17446579 complement(6434442..6436568) 1 NC_022657.1 COG1201 Lhr-like helicases; DEAD/DEAH box helicase domain-containing protein 6436568 17446579 AFR_29575 Actinoplanes friuliensis DSM 7358 DEAD/DEAH box helicase domain-containing protein YP_008737229.1 6434442 R 1246995 CDS YP_008737230.1 556568805 17446580 complement(6436565..6437878) 1 NC_022657.1 ATP/GTP-binding protein 6437878 17446580 AFR_29580 Actinoplanes friuliensis DSM 7358 ATP/GTP-binding protein YP_008737230.1 6436565 R 1246995 CDS YP_008737231.1 556568806 17446581 complement(6437875..6440601) 1 NC_022657.1 bacteriophage (PhiC31) resistance protein PglZ 6440601 17446581 AFR_29585 Actinoplanes friuliensis DSM 7358 bacteriophage (PhiC31) resistance protein PglZ YP_008737231.1 6437875 R 1246995 CDS YP_008737232.1 556568807 17446582 complement(6440598..6444326) 1 NC_022657.1 COG1483 Predicted ATPase (AAA+ superfamily); bacteriophage resistance protein PglY 6444326 17446582 AFR_29590 Actinoplanes friuliensis DSM 7358 bacteriophage resistance protein PglY YP_008737232.1 6440598 R 1246995 CDS YP_008737233.1 556568808 17446583 6444570..6446558 1 NC_022657.1 COG1479 Uncharacterized conserved protein; hypothetical protein 6446558 17446583 AFR_29595 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737233.1 6444570 D 1246995 CDS YP_008737234.1 556568809 17446584 6446601..6447746 1 NC_022657.1 COG4127 Uncharacterized conserved protein; hypothetical protein 6447746 17446584 AFR_29600 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737234.1 6446601 D 1246995 CDS YP_008737235.1 556568810 17446585 complement(6447793..6451374) 1 NC_022657.1 COG1002 Type II restriction enzyme, methylase subunits; hypothetical protein 6451374 17446585 AFR_29605 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737235.1 6447793 R 1246995 CDS YP_008737236.1 556568811 17446586 complement(6451487..6452143) 1 NC_022657.1 hypothetical protein 6452143 17446586 AFR_29610 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737236.1 6451487 R 1246995 CDS YP_008737237.1 556568812 17446587 complement(6452161..6456555) 1 NC_022657.1 COG0515 Serine/threonine protein kinase; serine/threonine protein kinase 6456555 17446587 AFR_29615 Actinoplanes friuliensis DSM 7358 serine/threonine protein kinase YP_008737237.1 6452161 R 1246995 CDS YP_008737238.1 556568813 17446589 complement(6457375..6458763) 1 NC_022657.1 COG1160 Predicted GTPases; GTP-binding protein Der 6458763 17446589 AFR_29620 Actinoplanes friuliensis DSM 7358 GTP-binding protein Der YP_008737238.1 6457375 R 1246995 CDS YP_008737239.1 556568814 17446590 complement(6458760..6459428) 1 NC_022657.1 COG0283 Cytidylate kinase; cytidylate kinase 6459428 cmk 17446590 cmk Actinoplanes friuliensis DSM 7358 cytidylate kinase YP_008737239.1 6458760 R 1246995 CDS YP_008737240.1 556568815 17446591 complement(6459510..6460250) 1 NC_022657.1 COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases; ribosomal large subunit pseudouridine synthase B 6460250 17446591 AFR_29630 Actinoplanes friuliensis DSM 7358 ribosomal large subunit pseudouridine synthase B YP_008737240.1 6459510 R 1246995 CDS YP_008737241.1 556568816 17446592 complement(6460237..6461571) 1 NC_022657.1 COG1386 Predicted transcriptional regulator containing the HTH domain; putative transcriptional regulator 6461571 17446592 AFR_29635 Actinoplanes friuliensis DSM 7358 putative transcriptional regulator YP_008737241.1 6460237 R 1246995 CDS YP_008737242.1 556568817 17446593 complement(6461568..6463655) 1 NC_022657.1 COG1354 Uncharacterized conserved protein; putative chromosome segregation and condensation protein A 6463655 17446593 AFR_29640 Actinoplanes friuliensis DSM 7358 putative chromosome segregation and condensation protein A YP_008737242.1 6461568 R 1246995 CDS YP_008737243.1 556568818 17446594 complement(6463797..6464492) 1 NC_022657.1 COG3231 Aminoglycoside phosphotransferase; aminoglycoside phosphotransferase 6464492 17446594 AFR_29645 Actinoplanes friuliensis DSM 7358 aminoglycoside phosphotransferase YP_008737243.1 6463797 R 1246995 CDS YP_008737244.1 556568819 17446595 6464528..6465133 1 NC_022657.1 COG0637 Predicted phosphatase/phosphohexomutase; putative haloacid dehalogenase-like hydrolase 6465133 17446595 AFR_29650 Actinoplanes friuliensis DSM 7358 putative haloacid dehalogenase-like hydrolase YP_008737244.1 6464528 D 1246995 CDS YP_008737245.1 556568820 17446596 6465176..6466060 1 NC_022657.1 hypothetical protein 6466060 17446596 AFR_29655 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737245.1 6465176 D 1246995 CDS YP_008737246.1 556568821 17446597 6466116..6466901 1 NC_022657.1 hypothetical protein 6466901 17446597 AFR_29660 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737246.1 6466116 D 1246995 CDS YP_008737247.1 556568822 17446598 6466930..6467610 1 NC_022657.1 hypothetical protein 6467610 17446598 AFR_29665 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737247.1 6466930 D 1246995 CDS YP_008737248.1 556568823 17446599 complement(6467787..6468233) 1 NC_022657.1 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; NUDIX hydrolase 6468233 17446599 AFR_29670 Actinoplanes friuliensis DSM 7358 NUDIX hydrolase YP_008737248.1 6467787 R 1246995 CDS YP_008737249.1 556568824 17446600 complement(6468505..6469407) 1 NC_022657.1 COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase; putative aminotransferase 6469407 17446600 AFR_29675 Actinoplanes friuliensis DSM 7358 putative aminotransferase YP_008737249.1 6468505 R 1246995 CDS YP_008737250.1 556568825 17446601 6469497..6470258 1 NC_022657.1 COG0317 Guanosine polyphosphate pyrophosphohydrolases/synthetases; GTP pyrophosphokinase 6470258 17446601 AFR_29680 Actinoplanes friuliensis DSM 7358 GTP pyrophosphokinase YP_008737250.1 6469497 D 1246995 CDS YP_008737251.1 556568826 17446602 complement(6470292..6471029) 1 NC_022657.1 hypothetical protein 6471029 17446602 AFR_29685 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737251.1 6470292 R 1246995 CDS YP_008737252.1 556568827 17446603 complement(6471615..6472739) 1 NC_022657.1 COG0553 Superfamily II DNA/RNA helicases, SNF2 family; hypothetical protein 6472739 17446603 AFR_29690 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737252.1 6471615 R 1246995 CDS YP_008737253.1 556568828 17446604 complement(6472736..6473008) 1 NC_022657.1 hypothetical protein 6473008 17446604 AFR_29695 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737253.1 6472736 R 1246995 CDS YP_008737254.1 556568829 17446605 complement(6473062..6473517) 1 NC_022657.1 COG0517 FOG: CBS domain; hypothetical protein 6473517 17446605 AFR_29700 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737254.1 6473062 R 1246995 CDS YP_008737255.1 556568830 17446606 6475742..6476851 1 NC_022657.1 transcriptional regulator 6476851 17446606 AFR_29705 Actinoplanes friuliensis DSM 7358 transcriptional regulator YP_008737255.1 6475742 D 1246995 CDS YP_008737256.1 556568831 17446607 6477099..6477314 1 NC_022657.1 hypothetical protein 6477314 17446607 AFR_29710 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737256.1 6477099 D 1246995 CDS YP_008737257.1 556568832 17446608 6477654..6478358 1 NC_022657.1 hypothetical protein 6478358 17446608 AFR_29715 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737257.1 6477654 D 1246995 CDS YP_008737258.1 556568833 17446609 complement(6478458..6479363) 1 NC_022657.1 COG0484 DnaJ-class molecular chaperone with C-terminal Zn finger domain; chaperone protein dnaj 6479363 17446609 AFR_29720 Actinoplanes friuliensis DSM 7358 chaperone protein dnaj YP_008737258.1 6478458 R 1246995 CDS YP_008737259.1 556568834 17446610 6480804..6481478 1 NC_022657.1 COG4195 Phage-related replication protein; hypothetical protein 6481478 17446610 AFR_29725 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737259.1 6480804 D 1246995 CDS YP_008737260.1 556568835 17446611 6481829..6483052 1 NC_022657.1 hypothetical protein 6483052 17446611 AFR_29730 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737260.1 6481829 D 1246995 CDS YP_008737261.1 556568836 17446612 complement(6483160..6483753) 1 NC_022657.1 COG1309 Transcriptional regulator; putative transcriptional regulator 6483753 17446612 AFR_29735 Actinoplanes friuliensis DSM 7358 putative transcriptional regulator YP_008737261.1 6483160 R 1246995 CDS YP_008737262.1 556568837 17446613 6483838..6484827 1 NC_022657.1 COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases; oxidoreductase 6484827 17446613 AFR_29740 Actinoplanes friuliensis DSM 7358 oxidoreductase YP_008737262.1 6483838 D 1246995 CDS YP_008737263.1 556568838 17446614 6484861..6485295 1 NC_022657.1 COG1846 Transcriptional regulators; MarR family transcriptional regulator 6485295 17446614 AFR_29745 Actinoplanes friuliensis DSM 7358 MarR family transcriptional regulator YP_008737263.1 6484861 D 1246995 CDS YP_008737264.1 556568839 17446615 6485292..6485726 1 NC_022657.1 hypothetical protein 6485726 17446615 AFR_29750 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737264.1 6485292 D 1246995 CDS YP_008737265.1 556568840 17446616 6486206..6486964 1 NC_022657.1 hypothetical protein 6486964 17446616 AFR_29755 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737265.1 6486206 D 1246995 CDS YP_008737266.1 556568841 17446617 complement(6486985..6487848) 1 NC_022657.1 COG0702 Predicted nucleoside-diphosphate-sugar epimerases; NAD-dependent epimerase/dehydratase 6487848 17446617 AFR_29760 Actinoplanes friuliensis DSM 7358 NAD-dependent epimerase/dehydratase YP_008737266.1 6486985 R 1246995 CDS YP_008737267.1 556568842 17446618 6487969..6488583 1 NC_022657.1 COG1309 Transcriptional regulator; TetR family transcriptional regulator 6488583 17446618 AFR_29765 Actinoplanes friuliensis DSM 7358 TetR family transcriptional regulator YP_008737267.1 6487969 D 1246995 CDS YP_008737268.1 556568843 17446619 complement(6488649..6489119) 1 NC_022657.1 COG1846 Transcriptional regulators; transcriptional regulator 6489119 17446619 AFR_29770 Actinoplanes friuliensis DSM 7358 transcriptional regulator YP_008737268.1 6488649 R 1246995 CDS YP_008737269.1 556568844 17446620 6489177..6489542 1 NC_022657.1 COG0346 Lactoylglutathione lyase and related lyases; glyoxalase/bleomycin resistance protein/dioxygenase 6489542 17446620 AFR_29775 Actinoplanes friuliensis DSM 7358 glyoxalase/bleomycin resistance protein/dioxygenase YP_008737269.1 6489177 D 1246995 CDS YP_008737270.1 556568845 17446621 6489539..6490456 1 NC_022657.1 COG0122 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase; HhH-GPD family protein 6490456 17446621 AFR_29780 Actinoplanes friuliensis DSM 7358 HhH-GPD family protein YP_008737270.1 6489539 D 1246995 CDS YP_008737271.1 556568846 17446622 complement(6490453..6490731) 1 NC_022657.1 COG0564 Pseudouridylate synthases, 23S RNA-specific; hypothetical protein 6490731 17446622 AFR_29785 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737271.1 6490453 R 1246995 CDS YP_008737272.1 556568847 17446623 complement(6490892..6491293) 1 NC_022657.1 COG0669 Phosphopantetheine adenylyltransferase; putative pantetheine-phosphate adenylyltransferase 6491293 17446623 AFR_29790 Actinoplanes friuliensis DSM 7358 putative pantetheine-phosphate adenylyltransferase YP_008737272.1 6490892 R 1246995 CDS YP_008737273.1 556568848 17446624 complement(6491298..6491936) 1 NC_022657.1 COG0564 Pseudouridylate synthases, 23S RNA-specific; hypothetical protein 6491936 17446624 AFR_29795 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737273.1 6491298 R 1246995 CDS YP_008737274.1 556568849 17446625 6492120..6492755 1 NC_022657.1 hypothetical protein 6492755 17446625 AFR_29800 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737274.1 6492120 D 1246995 CDS YP_008737275.1 556568850 17446626 complement(6492870..6493349) 1 NC_022657.1 hypothetical protein 6493349 17446626 AFR_29805 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737275.1 6492870 R 1246995 CDS YP_008737276.1 556568851 17446627 complement(6493455..6493664) 1 NC_022657.1 hypothetical protein 6493664 17446627 AFR_29810 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737276.1 6493455 R 1246995 CDS YP_008737277.1 556568852 17446628 6494053..6494406 1 NC_022657.1 hypothetical protein 6494406 17446628 AFR_29815 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737277.1 6494053 D 1246995 CDS YP_008737278.1 556568853 17446629 complement(6494515..6494637) 1 NC_022657.1 hypothetical protein 6494637 17446629 AFR_29820 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737278.1 6494515 R 1246995 CDS YP_008737279.1 556568854 17446630 complement(6496067..6496435) 1 NC_022657.1 hypothetical protein 6496435 17446630 AFR_29825 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737279.1 6496067 R 1246995 CDS YP_008737280.1 556568855 17446631 6496884..6497513 1 NC_022657.1 hypothetical protein 6497513 17446631 AFR_29830 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737280.1 6496884 D 1246995 CDS YP_008737281.1 556568856 17446632 6497626..6498102 1 NC_022657.1 hypothetical protein 6498102 17446632 AFR_29835 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737281.1 6497626 D 1246995 CDS YP_008737282.1 556568857 17446633 complement(6498074..6498856) 1 NC_022657.1 COG1305 Transglutaminase-like enzymes, putative cysteine proteases; hypothetical protein 6498856 17446633 AFR_29840 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737282.1 6498074 R 1246995 CDS YP_008737283.1 556568858 17446634 6498912..6499418 1 NC_022657.1 hypothetical protein 6499418 17446634 AFR_29845 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737283.1 6498912 D 1246995 CDS YP_008737284.1 556568859 17446635 6499542..6500162 1 NC_022657.1 hypothetical protein 6500162 17446635 AFR_29850 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737284.1 6499542 D 1246995 CDS YP_008737285.1 556568860 17446636 complement(6500140..6500841) 1 NC_022657.1 COG0463 Glycosyltransferases involved in cell wall biogenesis; family 2 glycosyl transferase 6500841 17446636 AFR_29855 Actinoplanes friuliensis DSM 7358 family 2 glycosyl transferase YP_008737285.1 6500140 R 1246995 CDS YP_008737286.1 556568861 17446637 complement(6500880..6501488) 1 NC_022657.1 COG1434 Uncharacterized conserved protein; hypothetical protein 6501488 17446637 AFR_29860 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737286.1 6500880 R 1246995 CDS YP_008737287.1 556568862 17446638 complement(6501505..6502188) 1 NC_022657.1 hypothetical protein 6502188 17446638 AFR_29865 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737287.1 6501505 R 1246995 CDS YP_008737288.1 556568863 17446639 complement(6502190..6503122) 1 NC_022657.1 COG1192 ATPases involved in chromosome partitioning; putative chromosome partitioning protein 6503122 17446639 AFR_29870 Actinoplanes friuliensis DSM 7358 putative chromosome partitioning protein YP_008737288.1 6502190 R 1246995 CDS YP_008737289.1 556568864 17446640 complement(6503235..6504146) 1 NC_022657.1 COG4974 Site-specific recombinase XerD; site-specific tyrosine recombinase XerD 6504146 xerD 17446640 xerD Actinoplanes friuliensis DSM 7358 site-specific tyrosine recombinase XerD YP_008737289.1 6503235 R 1246995 CDS YP_008737290.1 556568865 17446641 complement(6504155..6505270) 1 NC_022657.1 COG0686 Alanine dehydrogenase; putative L-alanine dehydrogenase 6505270 17446641 AFR_29880 Actinoplanes friuliensis DSM 7358 putative L-alanine dehydrogenase YP_008737290.1 6504155 R 1246995 CDS YP_008737291.1 556568866 17446642 6505479..6507881 1 NC_022657.1 COG0675 Transposase and inactivated derivatives; transposase, IS605 OrfB family protein 6507881 17446642 AFR_29885 Actinoplanes friuliensis DSM 7358 transposase, IS605 OrfB family protein YP_008737291.1 6505479 D 1246995 CDS YP_008737292.1 556568867 17446643 complement(6507901..6508497) 1 NC_022657.1 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; NUDIX hydrolase 6508497 17446643 AFR_29890 Actinoplanes friuliensis DSM 7358 NUDIX hydrolase YP_008737292.1 6507901 R 1246995 CDS YP_008737293.1 556568868 17446644 complement(6508494..6510212) 1 NC_022657.1 COG0504 CTP synthase (UTP-ammonia lyase); CTP synthetase 6510212 pyrG 17446644 pyrG Actinoplanes friuliensis DSM 7358 CTP synthetase YP_008737293.1 6508494 R 1246995 CDS YP_008737294.1 556568869 17446645 complement(6510342..6513098) 1 NC_022657.1 hypothetical protein 6513098 17446645 AFR_29900 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737294.1 6510342 R 1246995 CDS YP_008737295.1 556568870 17446646 complement(6513095..6514225) 1 NC_022657.1 COG0438 Glycosyltransferase; putative glycosyltransferase 6514225 17446646 AFR_29905 Actinoplanes friuliensis DSM 7358 putative glycosyltransferase YP_008737295.1 6513095 R 1246995 CDS YP_008737296.1 556568871 17446647 complement(6514222..6515880) 1 NC_022657.1 COG0728 Uncharacterized membrane protein, putative virulence factor; Virulence factor mviN 6515880 17446647 AFR_29910 Actinoplanes friuliensis DSM 7358 Virulence factor mviN YP_008737296.1 6514222 R 1246995 CDS YP_008737297.1 556568872 17446648 complement(6515877..6516743) 1 NC_022657.1 hypothetical protein 6516743 17446648 AFR_29915 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737297.1 6515877 R 1246995 CDS YP_008737298.1 556568873 17446649 complement(6517011..6517940) 1 NC_022657.1 COG0460 Homoserine dehydrogenase; putative channel-forming protein 6517940 17446649 AFR_29920 Actinoplanes friuliensis DSM 7358 putative channel-forming protein YP_008737298.1 6517011 R 1246995 CDS YP_008737299.1 556568874 17446650 complement(6517968..6519146) 1 NC_022657.1 COG4825 Uncharacterized membrane-anchored protein conserved in bacteria; hypothetical protein 6519146 17446650 AFR_29925 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737299.1 6517968 R 1246995 CDS YP_008737300.1 556568875 17446651 complement(6519359..6520552) 1 NC_022657.1 COG0675 Transposase and inactivated derivatives; transposase, IS891/IS1136/IS1341 6520552 17446651 AFR_29930 Actinoplanes friuliensis DSM 7358 transposase, IS891/IS1136/IS1341 YP_008737300.1 6519359 R 1246995 CDS YP_008737301.1 556568876 17446652 complement(6520752..6522509) 1 NC_022657.1 COG0497 ATPase involved in DNA repair; putative recombination and DNA repair protein RecN 6522509 17446652 AFR_29935 Actinoplanes friuliensis DSM 7358 putative recombination and DNA repair protein RecN YP_008737301.1 6520752 R 1246995 CDS YP_008737302.1 556568877 17446653 complement(6522643..6523512) 1 NC_022657.1 COG0061 Predicted sugar kinase; inorganic polyphosphate/ATP-NAD kinase 6523512 ppnK 17446653 ppnK Actinoplanes friuliensis DSM 7358 inorganic polyphosphate/ATP-NAD kinase YP_008737302.1 6522643 R 1246995 CDS YP_008737303.1 556568878 17446654 complement(6523527..6524387) 1 NC_022657.1 COG1189 Predicted rRNA methylase; putative rRNA methyltransferase 6524387 17446654 AFR_29945 Actinoplanes friuliensis DSM 7358 putative rRNA methyltransferase YP_008737303.1 6523527 R 1246995 CDS YP_008737304.1 556568879 17446655 complement(6524417..6524776) 1 NC_022657.1 hypothetical protein 6524776 17446655 AFR_29950 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737304.1 6524417 R 1246995 CDS YP_008737305.1 556568880 17446656 complement(6524773..6525612) 1 NC_022657.1 hypothetical protein 6525612 17446656 AFR_29955 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737305.1 6524773 R 1246995 CDS YP_008737306.1 556568881 17446657 6525735..6526070 1 NC_022657.1 hypothetical protein 6526070 17446657 AFR_29960 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737306.1 6525735 D 1246995 CDS YP_008737307.1 556568882 17446658 6526160..6527050 1 NC_022657.1 COG1131 ABC-type multidrug transport system, ATPase component; ABC transporter-like protein 6527050 17446658 AFR_29965 Actinoplanes friuliensis DSM 7358 ABC transporter-like protein YP_008737307.1 6526160 D 1246995 CDS YP_008737308.1 556568883 17446659 6527043..6527864 1 NC_022657.1 hypothetical protein 6527864 17446659 AFR_29970 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737308.1 6527043 D 1246995 CDS YP_008737309.1 556568884 17446660 6527870..6529153 1 NC_022657.1 COG4585 Signal transduction histidine kinase; histidine kinase 6529153 17446660 AFR_29975 Actinoplanes friuliensis DSM 7358 histidine kinase YP_008737309.1 6527870 D 1246995 CDS YP_008737310.1 556568885 17446661 6529333..6529977 1 NC_022657.1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; putative two-component system response regulator 6529977 17446661 AFR_29980 Actinoplanes friuliensis DSM 7358 putative two-component system response regulator YP_008737310.1 6529333 D 1246995 CDS YP_008737311.1 556568886 17446662 complement(6530056..6531039) 1 NC_022657.1 COG0647 Predicted sugar phosphatases of the HAD superfamily; NagD-like Protein 6531039 17446662 AFR_29985 Actinoplanes friuliensis DSM 7358 NagD-like Protein YP_008737311.1 6530056 R 1246995 CDS YP_008737312.1 556568887 17446663 complement(6531036..6531959) 1 NC_022657.1 hypothetical protein 6531959 17446663 AFR_29990 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737312.1 6531036 R 1246995 CDS YP_008737313.1 556568888 17446667 complement(6539994..6541271) 1 NC_022657.1 COG0162 Tyrosyl-tRNA synthetase; putative tyrosyl-tRNA synthetase 6541271 17446667 AFR_30000 Actinoplanes friuliensis DSM 7358 putative tyrosyl-tRNA synthetase YP_008737313.1 6539994 R 1246995 CDS YP_008737314.1 556568889 17446668 6541348..6541926 1 NC_022657.1 hypothetical protein 6541926 17446668 AFR_30005 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737314.1 6541348 D 1246995 CDS YP_008737315.1 556568890 17446669 6541934..6542452 1 NC_022657.1 hypothetical protein 6542452 17446669 AFR_30010 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737315.1 6541934 D 1246995 CDS YP_008737316.1 556568891 17446670 6542542..6543252 1 NC_022657.1 COG2326 Uncharacterized conserved protein; hypothetical protein 6543252 17446670 AFR_30015 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737316.1 6542542 D 1246995 CDS YP_008737317.1 556568892 17446671 complement(6543460..6544113) 1 NC_022657.1 COG0563 Adenylate kinase and related kinases; adenylate kinase 6544113 17446671 AFR_30020 Actinoplanes friuliensis DSM 7358 adenylate kinase YP_008737317.1 6543460 R 1246995 CDS YP_008737318.1 556568893 17446672 complement(6544128..6544694) 1 NC_022657.1 hypothetical protein 6544694 17446672 AFR_30025 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737318.1 6544128 R 1246995 CDS YP_008737319.1 556568894 17446673 complement(6544748..6545239) 1 NC_022657.1 hypothetical protein 6545239 17446673 AFR_30030 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737319.1 6544748 R 1246995 CDS YP_008737320.1 556568895 17446674 complement(6545273..6546490) 1 NC_022657.1 hypothetical protein 6546490 17446674 AFR_30035 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737320.1 6545273 R 1246995 CDS YP_008737321.1 556568896 17446675 6546605..6546844 1 NC_022657.1 hypothetical protein 6546844 17446675 AFR_30040 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737321.1 6546605 D 1246995 CDS YP_008737322.1 556568897 17446676 6546983..6547798 1 NC_022657.1 COG2340 Uncharacterized protein with SCP/PR1 domains; hypothetical protein 6547798 17446676 AFR_30045 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737322.1 6546983 D 1246995 CDS YP_008737323.1 556568898 17446677 6548036..6548470 1 NC_022657.1 PASTA domain containing protein 6548470 17446677 AFR_30050 Actinoplanes friuliensis DSM 7358 PASTA domain containing protein YP_008737323.1 6548036 D 1246995 CDS YP_008737324.1 556568899 17446678 6548520..6549125 1 NC_022657.1 COG2094 3-methyladenine DNA glycosylase; putative 3-methyladenine DNA glycosylase 6549125 17446678 AFR_30055 Actinoplanes friuliensis DSM 7358 putative 3-methyladenine DNA glycosylase YP_008737324.1 6548520 D 1246995 CDS YP_008737325.1 556568900 17446679 6549192..6549683 1 NC_022657.1 hypothetical protein 6549683 17446679 AFR_30060 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737325.1 6549192 D 1246995 CDS YP_008737326.1 556568901 17446680 6549783..6551312 1 NC_022657.1 Subtilisin-like protein serine protease-like protein 6551312 17446680 AFR_30065 Actinoplanes friuliensis DSM 7358 Subtilisin-like protein serine protease-like protein YP_008737326.1 6549783 D 1246995 CDS YP_008737327.1 556568902 17446681 6551414..6554512 1 NC_022657.1 COG3537 Putative alpha-1,2-mannosidase; Neuropilin-1 6554512 17446681 AFR_30070 Actinoplanes friuliensis DSM 7358 Neuropilin-1 YP_008737327.1 6551414 D 1246995 CDS YP_008737328.1 556568903 17446682 6554593..6554958 1 NC_022657.1 hypothetical protein 6554958 17446682 AFR_30075 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737328.1 6554593 D 1246995 CDS YP_008737329.1 556568904 17446683 complement(6554965..6555810) 1 NC_022657.1 COG0063 Predicted sugar kinase; carbohydrate kinase 6555810 17446683 AFR_30080 Actinoplanes friuliensis DSM 7358 carbohydrate kinase YP_008737329.1 6554965 R 1246995 CDS YP_008737330.1 556568905 17446684 complement(6555794..6556522) 1 NC_022657.1 COG0406 Fructose-2,6-bisphosphatase; phosphoglycerate mutase 6556522 17446684 AFR_30085 Actinoplanes friuliensis DSM 7358 phosphoglycerate mutase YP_008737330.1 6555794 R 1246995 CDS YP_008737331.1 556568906 17446685 6556721..6557392 1 NC_022657.1 COG3599 Cell division initiation protein; hypothetical protein 6557392 17446685 AFR_30090 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737331.1 6556721 D 1246995 CDS YP_008737332.1 556568907 17446686 6557535..6558833 1 NC_022657.1 COG1653 ABC-type sugar transport system, periplasmic component; extracellular solute-binding protein 6558833 17446686 AFR_30095 Actinoplanes friuliensis DSM 7358 extracellular solute-binding protein YP_008737332.1 6557535 D 1246995 CDS YP_008737333.1 556568908 17446687 6558845..6559783 1 NC_022657.1 COG1175 ABC-type sugar transport systems, permease components; Permease component of ABC-type sugar transporter 6559783 17446687 AFR_30100 Actinoplanes friuliensis DSM 7358 Permease component of ABC-type sugar transporter YP_008737333.1 6558845 D 1246995 CDS YP_008737334.1 556568909 17446688 6559789..6560631 1 NC_022657.1 COG0395 ABC-type sugar transport system, permease component; ABC transporter inner membrane protein 6560631 17446688 AFR_30105 Actinoplanes friuliensis DSM 7358 ABC transporter inner membrane protein YP_008737334.1 6559789 D 1246995 CDS YP_008737335.1 556568910 17446689 6560649..6562115 1 NC_022657.1 COG3534 Alpha-L-arabinofuranosidase; alpha-L-arabinofuranosidase 6562115 17446689 AFR_30110 Actinoplanes friuliensis DSM 7358 alpha-L-arabinofuranosidase YP_008737335.1 6560649 D 1246995 CDS YP_008737336.1 556568911 17446690 complement(6562108..6562593) 1 NC_022657.1 COG0490 Putative regulatory, ligand-binding protein related to C-terminal domains of K+ channels; TrkA-C domain-containing protein 6562593 17446690 AFR_30115 Actinoplanes friuliensis DSM 7358 TrkA-C domain-containing protein YP_008737336.1 6562108 R 1246995 CDS YP_008737337.1 556568912 17446691 6562778..6563713 1 NC_022657.1 COG3851 Signal transduction histidine kinase, glucose-6-phosphate specific; two-component system sensor kinase 6563713 17446691 AFR_30120 Actinoplanes friuliensis DSM 7358 two-component system sensor kinase YP_008737337.1 6562778 D 1246995 CDS YP_008737338.1 556568913 17446692 6563710..6564363 1 NC_022657.1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; two-component system response regulator 6564363 17446692 AFR_30125 Actinoplanes friuliensis DSM 7358 two-component system response regulator YP_008737338.1 6563710 D 1246995 CDS YP_008737339.1 556568914 17446693 6564404..6567187 1 NC_022657.1 COG1009 NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit; monovalent cation/H+ antiporter subunit A 6567187 17446693 AFR_30130 Actinoplanes friuliensis DSM 7358 monovalent cation/H+ antiporter subunit A YP_008737339.1 6564404 D 1246995 CDS YP_008737340.1 556568915 17446694 6567273..6567677 1 NC_022657.1 COG1006 Multisubunit Na+/H+ antiporter, MnhC subunit; NADH-ubiquinone oxidoreductase chain 4l 6567677 17446694 AFR_30135 Actinoplanes friuliensis DSM 7358 NADH-ubiquinone oxidoreductase chain 4l YP_008737340.1 6567273 D 1246995 CDS YP_008737341.1 556568916 17446695 6567674..6569179 1 NC_022657.1 COG0651 Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit; NADH/Ubiquinone/plastoquinone (complex I) 6569179 17446695 AFR_30140 Actinoplanes friuliensis DSM 7358 NADH/Ubiquinone/plastoquinone (complex I) YP_008737341.1 6567674 D 1246995 CDS YP_008737342.1 556568917 17446696 6569176..6569724 1 NC_022657.1 COG1863 Multisubunit Na+/H+ antiporter, MnhE subunit; monovalent cation/H+ antiporter subunit E 6569724 17446696 AFR_30145 Actinoplanes friuliensis DSM 7358 monovalent cation/H+ antiporter subunit E YP_008737342.1 6569176 D 1246995 CDS YP_008737343.1 556568918 17446697 6569721..6570113 1 NC_022657.1 COG2212 Multisubunit Na+/H+ antiporter, MnhF subunit; hypothetical protein 6570113 17446697 AFR_30150 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737343.1 6569721 D 1246995 CDS YP_008737344.1 556568919 17446698 6570110..6570532 1 NC_022657.1 COG1320 Multisubunit Na+/H+ antiporter, MnhG subunit; monovalent cation/proton antiporter subunit MnhG/PhaG 6570532 17446698 AFR_30155 Actinoplanes friuliensis DSM 7358 monovalent cation/proton antiporter subunit MnhG/PhaG YP_008737344.1 6570110 D 1246995 CDS YP_008737345.1 556568920 17446699 complement(6570447..6571205) 1 NC_022657.1 COG0639 Diadenosine tetraphosphatase and related serine/threonine protein phosphatases; metallophosphoesterase 6571205 17446699 AFR_30160 Actinoplanes friuliensis DSM 7358 metallophosphoesterase YP_008737345.1 6570447 R 1246995 CDS YP_008737346.1 556568921 17446700 6571335..6571646 1 NC_022657.1 hypothetical protein 6571646 17446700 AFR_30165 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737346.1 6571335 D 1246995 CDS YP_008737347.1 556568922 17446701 6571639..6572970 1 NC_022657.1 hypothetical protein 6572970 17446701 AFR_30170 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737347.1 6571639 D 1246995 CDS YP_008737348.1 556568923 17446702 6572967..6573839 1 NC_022657.1 hypothetical protein 6573839 17446702 AFR_30175 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737348.1 6572967 D 1246995 CDS YP_008737349.1 556568924 17446703 6573891..6574574 1 NC_022657.1 COG1011 Predicted hydrolase (HAD superfamily); haloacid dehalogenase domain-containing protein hydrolase 6574574 17446703 AFR_30180 Actinoplanes friuliensis DSM 7358 haloacid dehalogenase domain-containing protein hydrolase YP_008737349.1 6573891 D 1246995 CDS YP_008737350.1 556568925 17446704 complement(6574752..6575765) 1 NC_022657.1 COG0583 Transcriptional regulator; LysR family transcriptional regulator 6575765 17446704 AFR_30185 Actinoplanes friuliensis DSM 7358 LysR family transcriptional regulator YP_008737350.1 6574752 R 1246995 CDS YP_008737351.1 556568926 17446705 6575974..6576879 1 NC_022657.1 COG0730 Predicted permeases; hypothetical protein 6576879 17446705 AFR_30190 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737351.1 6575974 D 1246995 CDS YP_008737352.1 556568927 17446706 complement(6576869..6577207) 1 NC_022657.1 hypothetical protein 6577207 17446706 AFR_30195 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737352.1 6576869 R 1246995 CDS YP_008737353.1 556568928 17446707 complement(6577696..6578619) 1 NC_022657.1 COG1192 ATPases involved in chromosome partitioning; cobyrinic acid a,c-diamide synthase 6578619 17446707 AFR_30200 Actinoplanes friuliensis DSM 7358 cobyrinic acid a,c-diamide synthase YP_008737353.1 6577696 R 1246995 CDS YP_008737354.1 556568929 17446708 complement(6578787..6580217) 1 NC_022657.1 COG0165 Argininosuccinate lyase; argininosuccinate lyase 6580217 17446708 AFR_30205 Actinoplanes friuliensis DSM 7358 argininosuccinate lyase YP_008737354.1 6578787 R 1246995 CDS YP_008737355.1 556568930 17446709 complement(6580261..6581514) 1 NC_022657.1 COG0137 Argininosuccinate synthase; putative argininosuccinate synthase 6581514 17446709 AFR_30210 Actinoplanes friuliensis DSM 7358 putative argininosuccinate synthase YP_008737355.1 6580261 R 1246995 CDS YP_008737356.1 556568931 17446710 complement(6581524..6582405) 1 NC_022657.1 hypothetical protein 6582405 17446710 AFR_30215 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737356.1 6581524 R 1246995 CDS YP_008737357.1 556568932 17446711 complement(6582402..6582899) 1 NC_022657.1 COG1438 Arginine repressor; arginine repressor 6582899 17446711 AFR_30220 Actinoplanes friuliensis DSM 7358 arginine repressor YP_008737357.1 6582402 R 1246995 CDS YP_008737358.1 556568933 17446712 complement(6582896..6583825) 1 NC_022657.1 COG0078 Ornithine carbamoyltransferase; putative ornithine carbamoyltransferase 6583825 17446712 AFR_30225 Actinoplanes friuliensis DSM 7358 putative ornithine carbamoyltransferase YP_008737358.1 6582896 R 1246995 CDS YP_008737359.1 556568934 17446713 complement(6583822..6584979) 1 NC_022657.1 COG4992 Ornithine/acetylornithine aminotransferase; acetylornithine aminotransferase 6584979 argD 17446713 argD Actinoplanes friuliensis DSM 7358 acetylornithine aminotransferase YP_008737359.1 6583822 R 1246995 CDS YP_008737360.1 556568935 17446714 complement(6584976..6585842) 1 NC_022657.1 COG0548 Acetylglutamate kinase; acetylglutamate kinase 6585842 17446714 AFR_30235 Actinoplanes friuliensis DSM 7358 acetylglutamate kinase YP_008737360.1 6584976 R 1246995 CDS YP_008737361.1 556568936 17446715 complement(6585839..6587011) 1 NC_022657.1 COG1364 N-acetylglutamate synthase (N-acetylornithine aminotransferase); bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein 6587011 argJ 17446715 argJ Actinoplanes friuliensis DSM 7358 bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein YP_008737361.1 6585839 R 1246995 CDS YP_008737362.1 556568937 17446716 complement(6587008..6588009) 1 NC_022657.1 COG0002 Acetylglutamate semialdehyde dehydrogenase; putative N-acetylglutamate gamma-semialdehyde dehydrogenase 6588009 17446716 AFR_30245 Actinoplanes friuliensis DSM 7358 putative N-acetylglutamate gamma-semialdehyde dehydrogenase YP_008737362.1 6587008 R 1246995 CDS YP_008737363.1 556568938 17446717 complement(6588092..6588919) 1 NC_022657.1 hypothetical protein 6588919 17446717 AFR_30250 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737363.1 6588092 R 1246995 CDS YP_008737364.1 556568939 17446718 complement(6588922..6591024) 1 NC_022657.1 hypothetical protein 6591024 17446718 AFR_30255 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737364.1 6588922 R 1246995 CDS YP_008737365.1 556568940 17446719 complement(6591114..6591860) 1 NC_022657.1 COG0583 Transcriptional regulator; hypothetical protein 6591860 17446719 AFR_30260 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737365.1 6591114 R 1246995 CDS YP_008737366.1 556568941 17446720 6592054..6592557 1 NC_022657.1 hypothetical protein 6592557 17446720 AFR_30265 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737366.1 6592054 D 1246995 CDS YP_008737367.1 556568942 17446721 6592647..6593318 1 NC_022657.1 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases; cyclic nucleotide-binding protein 6593318 17446721 AFR_30270 Actinoplanes friuliensis DSM 7358 cyclic nucleotide-binding protein YP_008737367.1 6592647 D 1246995 CDS YP_008737368.1 556568943 17446722 complement(6593322..6594026) 1 NC_022657.1 hypothetical protein 6594026 17446722 AFR_30275 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737368.1 6593322 R 1246995 CDS YP_008737369.1 556568944 17446723 complement(6594043..6594882) 1 NC_022657.1 COG1396 Predicted transcriptional regulators; helix-turn-helix domain-containing protein 6594882 17446723 AFR_30280 Actinoplanes friuliensis DSM 7358 helix-turn-helix domain-containing protein YP_008737369.1 6594043 R 1246995 CDS YP_008737370.1 556568945 17446724 complement(6594936..6595529) 1 NC_022657.1 COG1309 Transcriptional regulator; TetR family transcriptional regulator 6595529 17446724 AFR_30285 Actinoplanes friuliensis DSM 7358 TetR family transcriptional regulator YP_008737370.1 6594936 R 1246995 CDS YP_008737371.1 556568946 17446725 6595628..6596812 1 NC_022657.1 COG2124 Cytochrome P450; cytochrome P450 6596812 17446725 AFR_30290 Actinoplanes friuliensis DSM 7358 cytochrome P450 YP_008737371.1 6595628 D 1246995 CDS YP_008737372.1 556568947 17446726 6596809..6597006 1 NC_022657.1 COG1141 Ferredoxin; Ferredoxin fas2 6597006 17446726 AFR_30295 Actinoplanes friuliensis DSM 7358 Ferredoxin fas2 YP_008737372.1 6596809 D 1246995 CDS YP_008737373.1 556568948 17446727 complement(6597028..6597813) 1 NC_022657.1 hypothetical protein 6597813 17446727 AFR_30300 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737373.1 6597028 R 1246995 CDS YP_008737374.1 556568949 17446728 complement(6597810..6598715) 1 NC_022657.1 COG1131 ABC-type multidrug transport system, ATPase component; ABC transporter 6598715 17446728 AFR_30305 Actinoplanes friuliensis DSM 7358 ABC transporter YP_008737374.1 6597810 R 1246995 CDS YP_008737375.1 556568950 17446729 6598785..6599969 1 NC_022657.1 COG4564 Signal transduction histidine kinase; two-component system sensor kinase 6599969 17446729 AFR_30310 Actinoplanes friuliensis DSM 7358 two-component system sensor kinase YP_008737375.1 6598785 D 1246995 CDS YP_008737376.1 556568951 17446730 6599966..6600625 1 NC_022657.1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; LuxR family two component transcriptional regulator 6600625 17446730 AFR_30315 Actinoplanes friuliensis DSM 7358 LuxR family two component transcriptional regulator YP_008737376.1 6599966 D 1246995 CDS YP_008737377.1 556568952 17446731 6600636..6600869 1 NC_022657.1 hypothetical protein 6600869 17446731 AFR_30320 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737377.1 6600636 D 1246995 CDS YP_008737378.1 556568953 17446732 6601042..6603324 1 NC_022657.1 COG1472 Beta-glucosidase-related glycosidases; putative glycosyl hydrolase 6603324 17446732 AFR_30325 Actinoplanes friuliensis DSM 7358 putative glycosyl hydrolase YP_008737378.1 6601042 D 1246995 CDS YP_008737379.1 556568954 17446733 6603324..6604241 1 NC_022657.1 aminoglycoside phosphotransferase 6604241 17446733 AFR_30330 Actinoplanes friuliensis DSM 7358 aminoglycoside phosphotransferase YP_008737379.1 6603324 D 1246995 CDS YP_008737380.1 556568955 17446734 6604238..6605083 1 NC_022657.1 COG0451 Nucleoside-diphosphate-sugar epimerases; NAD-dependent epimerase/dehydratase 6605083 17446734 AFR_30335 Actinoplanes friuliensis DSM 7358 NAD-dependent epimerase/dehydratase YP_008737380.1 6604238 D 1246995 CDS YP_008737381.1 556568956 17446735 6605107..6606414 1 NC_022657.1 COG0205 6-phosphofructokinase; diphosphate--fructose-6-phosphate 1-phosphotransferase 6606414 17446735 AFR_30340 Actinoplanes friuliensis DSM 7358 diphosphate--fructose-6-phosphate 1-phosphotransferase YP_008737381.1 6605107 D 1246995 CDS YP_008737382.1 556568957 17446736 complement(6606404..6607111) 1 NC_022657.1 COG3393 Predicted acetyltransferase; hypothetical protein 6607111 17446736 AFR_30345 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737382.1 6606404 R 1246995 CDS YP_008737383.1 556568958 17446737 6607132..6607836 1 NC_022657.1 COG2949 Uncharacterized membrane protein; hypothetical protein 6607836 17446737 AFR_30350 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737383.1 6607132 D 1246995 CDS YP_008737384.1 556568959 17446738 6607864..6608634 1 NC_022657.1 COG1136 ABC-type antimicrobial peptide transport system, ATPase component; ABC transporter ATP-binding protein 6608634 17446738 AFR_30355 Actinoplanes friuliensis DSM 7358 ABC transporter ATP-binding protein YP_008737384.1 6607864 D 1246995 CDS YP_008737385.1 556568960 17446739 6608732..6610051 1 NC_022657.1 COG4591 ABC-type transport system, involved in lipoprotein release, permease component; hypothetical protein 6610051 17446739 AFR_30360 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737385.1 6608732 D 1246995 CDS YP_008737386.1 556568961 17446740 6610048..6611349 1 NC_022657.1 COG4585 Signal transduction histidine kinase; Phytochrome 1 6611349 17446740 AFR_30365 Actinoplanes friuliensis DSM 7358 Phytochrome 1 YP_008737386.1 6610048 D 1246995 CDS YP_008737387.1 556568962 17446741 6611351..6611995 1 NC_022657.1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; LuxR family transcriptional regulator 6611995 17446741 AFR_30370 Actinoplanes friuliensis DSM 7358 LuxR family transcriptional regulator YP_008737387.1 6611351 D 1246995 CDS YP_008737388.1 556568963 17446742 6612051..6613058 1 NC_022657.1 COG2367 Beta-lactamase class A; hypothetical protein 6613058 17446742 AFR_30375 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737388.1 6612051 D 1246995 CDS YP_008737389.1 556568964 17446743 6613088..6615196 1 NC_022657.1 putative amino acid transporter 6615196 17446743 AFR_30380 Actinoplanes friuliensis DSM 7358 putative amino acid transporter YP_008737389.1 6613088 D 1246995 CDS YP_008737390.1 556568965 17446744 6615248..6615643 1 NC_022657.1 COG1725 Predicted transcriptional regulators; GntR family transcriptional regulator 6615643 17446744 AFR_30385 Actinoplanes friuliensis DSM 7358 GntR family transcriptional regulator YP_008737390.1 6615248 D 1246995 CDS YP_008737391.1 556568966 17446745 6615640..6616521 1 NC_022657.1 COG1131 ABC-type multidrug transport system, ATPase component; ABC transporter-like protein 6616521 17446745 AFR_30390 Actinoplanes friuliensis DSM 7358 ABC transporter-like protein YP_008737391.1 6615640 D 1246995 CDS YP_008737392.1 556568967 17446746 6616518..6617483 1 NC_022657.1 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component; transmembrane transporter 6617483 17446746 AFR_30395 Actinoplanes friuliensis DSM 7358 transmembrane transporter YP_008737392.1 6616518 D 1246995 CDS YP_008737393.1 556568968 17446747 complement(6617495..6618505) 1 NC_022657.1 hypothetical protein 6618505 17446747 AFR_30400 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737393.1 6617495 R 1246995 CDS YP_008737394.1 556568969 17446748 complement(6618579..6619037) 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); hypothetical protein 6619037 17446748 AFR_30405 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737394.1 6618579 R 1246995 CDS YP_008737395.1 556568970 17446749 6619139..6620545 1 NC_022657.1 COG2234 Predicted aminopeptidases; peptidase M28 6620545 17446749 AFR_30410 Actinoplanes friuliensis DSM 7358 peptidase M28 YP_008737395.1 6619139 D 1246995 CDS YP_008737396.1 556568971 17446750 complement(6620550..6621164) 1 NC_022657.1 COG0500 SAM-dependent methyltransferases; hypothetical protein 6621164 17446750 AFR_30415 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737396.1 6620550 R 1246995 CDS YP_008737397.1 556568972 17446751 6621249..6621545 1 NC_022657.1 COG1359 Uncharacterized conserved protein; hypothetical protein 6621545 17446751 AFR_30420 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737397.1 6621249 D 1246995 CDS YP_008737398.1 556568973 17446752 6621542..6622009 1 NC_022657.1 hypothetical protein 6622009 17446752 AFR_30425 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737398.1 6621542 D 1246995 CDS YP_008737399.1 556568974 17446753 6622011..6622757 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); putative short-chain dehydrogenase 6622757 17446753 AFR_30430 Actinoplanes friuliensis DSM 7358 putative short-chain dehydrogenase YP_008737399.1 6622011 D 1246995 CDS YP_008737400.1 556568975 17446754 6622775..6623542 1 NC_022657.1 hypothetical protein 6623542 17446754 AFR_30435 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737400.1 6622775 D 1246995 CDS YP_008737401.1 556568976 17446755 complement(6623608..6626085) 1 NC_022657.1 COG0073 EMAP domain; phenylalanyl-tRNA ligase subunit beta 6626085 pheT 17446755 pheT Actinoplanes friuliensis DSM 7358 phenylalanyl-tRNA ligase subunit beta YP_008737401.1 6623608 R 1246995 CDS YP_008737402.1 556568977 17446756 complement(6626088..6627149) 1 NC_022657.1 COG0016 Phenylalanyl-tRNA synthetase alpha subunit; phenylalanyl-tRNA ligase subunit alpha 6627149 pheS 17446756 pheS Actinoplanes friuliensis DSM 7358 phenylalanyl-tRNA ligase subunit alpha YP_008737402.1 6626088 R 1246995 CDS YP_008737403.1 556568978 17446757 complement(6627472..6628248) 1 NC_022657.1 COG0566 rRNA methylases; putative rRNA methylase 6628248 17446757 AFR_30450 Actinoplanes friuliensis DSM 7358 putative rRNA methylase YP_008737403.1 6627472 R 1246995 CDS YP_008737404.1 556568979 17446758 complement(6628318..6628710) 1 NC_022657.1 COG0292 Ribosomal protein L20; 50S ribosomal protein L20 6628710 rplT 17446758 rplT Actinoplanes friuliensis DSM 7358 50S ribosomal protein L20 YP_008737404.1 6628318 R 1246995 CDS YP_008737405.1 556568980 17446759 complement(6628750..6628944) 1 NC_022657.1 COG0291 Ribosomal protein L35; 50S ribosomal protein L35 6628944 rpmI 17446759 rpmI Actinoplanes friuliensis DSM 7358 50S ribosomal protein L35 YP_008737405.1 6628750 R 1246995 CDS YP_008737406.1 556568981 17446760 complement(6628964..6629569) 1 NC_022657.1 COG0290 Translation initiation factor 3 (IF-3); translation initiation factor IF-3 6629569 infC 17446760 infC Actinoplanes friuliensis DSM 7358 translation initiation factor IF-3 YP_008737406.1 6628964 R 1246995 CDS YP_008737407.1 556568982 17446761 complement(6629862..6630290) 1 NC_022657.1 hypothetical protein 6630290 17446761 AFR_30470 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737407.1 6629862 R 1246995 CDS YP_008737408.1 556568983 17446762 complement(6630331..6631176) 1 NC_022657.1 COG0040 ATP phosphoribosyltransferase; ATP phosphoribosyltransferase 6631176 hisG 17446762 hisG Actinoplanes friuliensis DSM 7358 ATP phosphoribosyltransferase YP_008737408.1 6630331 R 1246995 CDS YP_008737409.1 556568984 17446763 complement(6631220..6631483) 1 NC_022657.1 COG0140 Phosphoribosyl-ATP pyrophosphohydrolase; phosphoribosyl-ATP pyrophosphatase 6631483 hisE 17446763 hisE Actinoplanes friuliensis DSM 7358 phosphoribosyl-ATP pyrophosphatase YP_008737409.1 6631220 R 1246995 CDS YP_008737410.1 556568985 17446764 6631562..6632437 1 NC_022657.1 COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; putative ABC transporter substrate-binding protein 6632437 17446764 AFR_30485 Actinoplanes friuliensis DSM 7358 putative ABC transporter substrate-binding protein YP_008737410.1 6631562 D 1246995 CDS YP_008737411.1 556568986 17446765 6632434..6633282 1 NC_022657.1 COG0765 ABC-type amino acid transport system, permease component; ABC transporter permease 6633282 17446765 AFR_30490 Actinoplanes friuliensis DSM 7358 ABC transporter permease YP_008737411.1 6632434 D 1246995 CDS YP_008737412.1 556568987 17446766 6633282..6634022 1 NC_022657.1 COG1126 ABC-type polar amino acid transport system, ATPase component; ABC transporter ATP-binding protein 6634022 17446766 AFR_30495 Actinoplanes friuliensis DSM 7358 ABC transporter ATP-binding protein YP_008737412.1 6633282 D 1246995 CDS YP_008737413.1 556568988 17446767 complement(6634019..6635125) 1 NC_022657.1 COG2133 Glucose/sorbosone dehydrogenases; putative oxidoreductase 6635125 17446767 AFR_30500 Actinoplanes friuliensis DSM 7358 putative oxidoreductase YP_008737413.1 6634019 R 1246995 CDS YP_008737414.1 556568989 17446768 complement(6635191..6635664) 1 NC_022657.1 COG0054 Riboflavin synthase beta-chain; 6,7-dimethyl-8-ribityllumazine synthase 6635664 ribH 17446768 ribH Actinoplanes friuliensis DSM 7358 6,7-dimethyl-8-ribityllumazine synthase YP_008737414.1 6635191 R 1246995 CDS YP_008737415.1 556568990 17446769 complement(6635720..6636925) 1 NC_022657.1 COG0108 3,4-dihydroxy-2-butanone 4-phosphate synthase; bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein 6636925 17446769 AFR_30510 Actinoplanes friuliensis DSM 7358 bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein YP_008737415.1 6635720 R 1246995 CDS YP_008737416.1 556568991 17446770 complement(6636915..6637517) 1 NC_022657.1 COG0307 Riboflavin synthase alpha chain; riboflavin synthase subunit alpha 6637517 17446770 AFR_30515 Actinoplanes friuliensis DSM 7358 riboflavin synthase subunit alpha YP_008737416.1 6636915 R 1246995 CDS YP_008737417.1 556568992 17446771 complement(6637517..6638572) 1 NC_022657.1 COG0117 Pyrimidine deaminase; diaminohydroxyphosphoribosylaminopyrimidine deaminase / 5-amino-6-(5-phosphoribosylamino)uracil reductase 6638572 17446771 AFR_30520 Actinoplanes friuliensis DSM 7358 diaminohydroxyphosphoribosylaminopyrimidine deaminase / 5-amino-6-(5-phosphoribosylamino)uracil reductase YP_008737417.1 6637517 R 1246995 CDS YP_008737418.1 556568993 17446772 complement(6638950..6639975) 1 NC_022657.1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Chemotaxis response regulator protein-glutamate methylesterase 6639975 17446772 AFR_30525 Actinoplanes friuliensis DSM 7358 Chemotaxis response regulator protein-glutamate methylesterase YP_008737418.1 6638950 R 1246995 CDS YP_008737419.1 556568994 17446773 complement(6639984..6640661) 1 NC_022657.1 COG0036 Pentose-5-phosphate-3-epimerase; putative ribulose-phosphate 3-epimerase 6640661 17446773 AFR_30530 Actinoplanes friuliensis DSM 7358 putative ribulose-phosphate 3-epimerase YP_008737419.1 6639984 R 1246995 CDS YP_008737420.1 556568995 17446774 6640728..6641606 1 NC_022657.1 hypothetical protein 6641606 17446774 AFR_30535 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737420.1 6640728 D 1246995 CDS YP_008737421.1 556568996 17446775 complement(6641721..6642359) 1 NC_022657.1 hypothetical protein 6642359 17446775 AFR_30540 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737421.1 6641721 R 1246995 CDS YP_008737422.1 556568997 17446776 complement(6642408..6643928) 1 NC_022657.1 COG0144 tRNA and rRNA cytosine-C5-methylases; ribosomal RNA small subunit methyltransferase B 6643928 17446776 AFR_30545 Actinoplanes friuliensis DSM 7358 ribosomal RNA small subunit methyltransferase B YP_008737422.1 6642408 R 1246995 CDS YP_008737423.1 556568998 17446777 complement(6643925..6644851) 1 NC_022657.1 COG0223 Methionyl-tRNA formyltransferase; methionyl-tRNA formyltransferase 6644851 17446777 AFR_30550 Actinoplanes friuliensis DSM 7358 methionyl-tRNA formyltransferase YP_008737423.1 6643925 R 1246995 CDS YP_008737424.1 556568999 17446778 complement(6644856..6645413) 1 NC_022657.1 COG0242 N-formylmethionyl-tRNA deformylase; peptide deformylase 6645413 def 17446778 def Actinoplanes friuliensis DSM 7358 peptide deformylase YP_008737424.1 6644856 R 1246995 CDS YP_008737425.1 556569000 17446779 complement(6645459..6646676) 1 NC_022657.1 COG2124 Cytochrome P450; Cytochrome P450 protein 6646676 17446779 AFR_30560 Actinoplanes friuliensis DSM 7358 Cytochrome P450 protein YP_008737425.1 6645459 R 1246995 CDS YP_008737426.1 556569001 17446780 6646781..6647923 1 NC_022657.1 COG4222 Uncharacterized protein conserved in bacteria; hypothetical protein 6647923 17446780 AFR_30565 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737426.1 6646781 D 1246995 CDS YP_008737427.1 556569002 17446781 complement(6648011..6650515) 1 NC_022657.1 COG1198 Primosomal protein N' (replication factor Y) - superfamily II helicase; primosomal protein N' 6650515 17446781 AFR_30570 Actinoplanes friuliensis DSM 7358 primosomal protein N' YP_008737427.1 6648011 R 1246995 CDS YP_008737428.1 556569003 17446782 complement(6650611..6651801) 1 NC_022657.1 COG0192 S-adenosylmethionine synthetase; S-adenosylmethionine synthetase 6651801 17446782 AFR_30575 Actinoplanes friuliensis DSM 7358 S-adenosylmethionine synthetase YP_008737428.1 6650611 R 1246995 CDS YP_008737429.1 556569004 17446783 complement(6651879..6653108) 1 NC_022657.1 COG0452 Phosphopantothenoylcysteine synthetase/decarboxylase; bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase 6653108 17446783 AFR_30580 Actinoplanes friuliensis DSM 7358 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase YP_008737429.1 6651879 R 1246995 CDS YP_008737430.1 556569005 17446784 complement(6653170..6653433) 1 NC_022657.1 COG1758 DNA-directed RNA polymerase, subunit K/omega; DNA-directed RNA polymerase subunit omega 6653433 rpoZ 17446784 rpoZ Actinoplanes friuliensis DSM 7358 DNA-directed RNA polymerase subunit omega YP_008737430.1 6653170 R 1246995 CDS YP_008737431.1 556569006 17446785 complement(6653511..6654113) 1 NC_022657.1 COG0194 Guanylate kinase; guanylate kinase 6654113 17446785 AFR_30590 Actinoplanes friuliensis DSM 7358 guanylate kinase YP_008737431.1 6653511 R 1246995 CDS YP_008737432.1 556569007 17446786 complement(6654146..6654463) 1 NC_022657.1 COG0099 Ribosomal protein S13; hypothetical protein 6654463 17446786 AFR_30595 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737432.1 6654146 R 1246995 CDS YP_008737433.1 556569008 17446787 complement(6654647..6655477) 1 NC_022657.1 COG0284 Orotidine-5'-phosphate decarboxylase; orotidine 5'-phosphate decarboxylase 6655477 pyrF 17446787 pyrF Actinoplanes friuliensis DSM 7358 orotidine 5'-phosphate decarboxylase YP_008737433.1 6654647 R 1246995 CDS YP_008737434.1 556569009 17446788 complement(6655498..6656760) 1 NC_022657.1 COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; adenosylmethionine-8-amino-7-oxononanoate aminotransferase 6656760 17446788 AFR_30605 Actinoplanes friuliensis DSM 7358 adenosylmethionine-8-amino-7-oxononanoate aminotransferase YP_008737434.1 6655498 R 1246995 CDS YP_008737435.1 556569010 17446789 complement(6657284..6658312) 1 NC_022657.1 COG0167 Dihydroorotate dehydrogenase; dihydroorotate dehydrogenase 2 6658312 17446789 AFR_30610 Actinoplanes friuliensis DSM 7358 dihydroorotate dehydrogenase 2 YP_008737435.1 6657284 R 1246995 CDS YP_008737436.1 556569011 17446790 complement(6658309..6661620) 1 NC_022657.1 COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); putative carbamoyl-phosphate synthase large subunit 6661620 17446790 AFR_30615 Actinoplanes friuliensis DSM 7358 putative carbamoyl-phosphate synthase large subunit YP_008737436.1 6658309 R 1246995 CDS YP_008737437.1 556569012 17446791 complement(6661620..6662714) 1 NC_022657.1 COG0505 Carbamoylphosphate synthase small subunit; putative carbamoyl-phosphate synthase small subunit 6662714 17446791 AFR_30620 Actinoplanes friuliensis DSM 7358 putative carbamoyl-phosphate synthase small subunit YP_008737437.1 6661620 R 1246995 CDS YP_008737438.1 556569013 17446792 complement(6662729..6663994) 1 NC_022657.1 COG0044 Dihydroorotase and related cyclic amidohydrolases; dihydroorotase 6663994 pyrC 17446792 pyrC Actinoplanes friuliensis DSM 7358 dihydroorotase YP_008737438.1 6662729 R 1246995 CDS YP_008737439.1 556569014 17446793 complement(6663991..6664914) 1 NC_022657.1 COG0540 Aspartate carbamoyltransferase, catalytic chain; aspartate carbamoyltransferase catalytic subunit 6664914 pyrB 17446793 pyrB Actinoplanes friuliensis DSM 7358 aspartate carbamoyltransferase catalytic subunit YP_008737439.1 6663991 R 1246995 CDS YP_008737440.1 556569015 17446794 complement(6664911..6665495) 1 NC_022657.1 COG2065 Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase; bifunctional pyrimidine regulatory protein PyrR uracil phosphoribosyltransferase 6665495 17446794 AFR_30635 Actinoplanes friuliensis DSM 7358 bifunctional pyrimidine regulatory protein PyrR uracil phosphoribosyltransferase YP_008737440.1 6664911 R 1246995 CDS YP_008737441.1 556569016 17446795 6665785..6666273 1 NC_022657.1 COG1396 Predicted transcriptional regulators; XRE family transcriptional regulator 6666273 17446795 AFR_30640 Actinoplanes friuliensis DSM 7358 XRE family transcriptional regulator YP_008737441.1 6665785 D 1246995 CDS YP_008737442.1 556569017 17446796 complement(6666796..6667206) 1 NC_022657.1 COG0781 Transcription termination factor; transcription antitermination protein NusB 6667206 nusB 17446796 nusB Actinoplanes friuliensis DSM 7358 transcription antitermination protein NusB YP_008737442.1 6666796 R 1246995 CDS YP_008737443.1 556569018 17446797 complement(6667230..6667787) 1 NC_022657.1 COG0231 Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A); translation elongation factor p 6667787 17446797 AFR_30650 Actinoplanes friuliensis DSM 7358 translation elongation factor p YP_008737443.1 6667230 R 1246995 CDS YP_008737444.1 556569019 17446798 complement(6667863..6668291) 1 NC_022657.1 COG0757 3-dehydroquinate dehydratase II; 3-dehydroquinate dehydratase 6668291 17446798 AFR_30655 Actinoplanes friuliensis DSM 7358 3-dehydroquinate dehydratase YP_008737444.1 6667863 R 1246995 CDS YP_008737445.1 556569020 17446799 complement(6668288..6669364) 1 NC_022657.1 COG0337 3-dehydroquinate synthetase; 3-dehydroquinate synthase 6669364 aroB 17446799 aroB Actinoplanes friuliensis DSM 7358 3-dehydroquinate synthase YP_008737445.1 6668288 R 1246995 CDS YP_008737446.1 556569021 17446800 6669450..6670148 1 NC_022657.1 COG0542 ATPases with chaperone activity, ATP-binding subunit; hypothetical protein 6670148 17446800 AFR_30665 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737446.1 6669450 D 1246995 CDS YP_008737447.1 556569022 17446801 complement(6670140..6671114) 1 NC_022657.1 COG2378 Predicted transcriptional regulator; helix-turn-helix type 11 domain-containing protein 6671114 17446801 AFR_30670 Actinoplanes friuliensis DSM 7358 helix-turn-helix type 11 domain-containing protein YP_008737447.1 6670140 R 1246995 CDS YP_008737448.1 556569023 17446802 6671178..6671879 1 NC_022657.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); esterase 6671879 17446802 AFR_30675 Actinoplanes friuliensis DSM 7358 esterase YP_008737448.1 6671178 D 1246995 CDS YP_008737449.1 556569024 17446803 complement(6671850..6672359) 1 NC_022657.1 COG0703 Shikimate kinase; shikimate kinase 6672359 aroK 17446803 aroK Actinoplanes friuliensis DSM 7358 shikimate kinase YP_008737449.1 6671850 R 1246995 CDS YP_008737450.1 556569025 17446804 complement(6672359..6673537) 1 NC_022657.1 COG0082 Chorismate synthase; chorismate synthase 6673537 17446804 AFR_30685 Actinoplanes friuliensis DSM 7358 chorismate synthase YP_008737450.1 6672359 R 1246995 CDS YP_008737451.1 556569026 17446805 6673658..6674869 1 NC_022657.1 COG0477 Permeases of the major facilitator superfamily; putative MFS transporter 6674869 17446805 AFR_30690 Actinoplanes friuliensis DSM 7358 putative MFS transporter YP_008737451.1 6673658 D 1246995 CDS YP_008737452.1 556569027 17446806 complement(6674944..6675759) 1 NC_022657.1 COG0169 Shikimate 5-dehydrogenase; putative shikimate 5-dehydrogenase 6675759 17446806 AFR_30695 Actinoplanes friuliensis DSM 7358 putative shikimate 5-dehydrogenase YP_008737452.1 6674944 R 1246995 CDS YP_008737453.1 556569028 17446807 complement(6675756..6676943) 1 NC_022657.1 COG1559 Predicted periplasmic solute-binding protein; putative aminodeoxychorismate lyase 6676943 17446807 AFR_30700 Actinoplanes friuliensis DSM 7358 putative aminodeoxychorismate lyase YP_008737453.1 6675756 R 1246995 CDS YP_008737454.1 556569029 17446808 complement(6676940..6677401) 1 NC_022657.1 COG0816 Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis); Holliday junction resolvase-like protein 6677401 17446808 AFR_30705 Actinoplanes friuliensis DSM 7358 Holliday junction resolvase-like protein YP_008737454.1 6676940 R 1246995 CDS YP_008737455.1 556569030 17446809 complement(6677418..6680102) 1 NC_022657.1 COG0013 Alanyl-tRNA synthetase; alanyl-tRNA ligase 6680102 alaS 17446809 alaS Actinoplanes friuliensis DSM 7358 alanyl-tRNA ligase YP_008737455.1 6677418 R 1246995 CDS YP_008737456.1 556569031 17446810 complement(6680099..6680404) 1 NC_022657.1 hypothetical protein 6680404 17446810 AFR_30715 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737456.1 6680099 R 1246995 CDS YP_008737457.1 556569032 17446811 complement(6680433..6680897) 1 NC_022657.1 hypothetical protein 6680897 17446811 AFR_30720 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737457.1 6680433 R 1246995 CDS YP_008737458.1 556569033 17446812 complement(6680977..6681843) 1 NC_022657.1 Collagen alpha-5(VI) chain 6681843 17446812 AFR_30725 Actinoplanes friuliensis DSM 7358 Collagen alpha-5(VI) chain YP_008737458.1 6680977 R 1246995 CDS YP_008737459.1 556569034 17446813 6681931..6684150 1 NC_022657.1 hypothetical protein 6684150 17446813 AFR_30730 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737459.1 6681931 D 1246995 CDS YP_008737460.1 556569035 17446814 6684280..6685041 1 NC_022657.1 hypothetical protein 6685041 17446814 AFR_30735 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737460.1 6684280 D 1246995 CDS YP_008737461.1 556569036 17446815 complement(6685590..6687347) 1 NC_022657.1 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase; recombination factor protein RarA 6687347 17446815 AFR_30740 Actinoplanes friuliensis DSM 7358 recombination factor protein RarA YP_008737461.1 6685590 R 1246995 CDS YP_008737462.1 556569037 17446816 complement(6687424..6687648) 1 NC_022657.1 hypothetical protein 6687648 17446816 AFR_30745 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737462.1 6687424 R 1246995 CDS YP_008737463.1 556569038 17446817 complement(6687749..6689026) 1 NC_022657.1 COG0477 Permeases of the major facilitator superfamily; putative MFS transporter 6689026 17446817 AFR_30750 Actinoplanes friuliensis DSM 7358 putative MFS transporter YP_008737463.1 6687749 R 1246995 CDS YP_008737464.1 556569039 17446818 complement(6689023..6689598) 1 NC_022657.1 COG0640 Predicted transcriptional regulators; putative ArsR-family transcriptional regulator 6689598 17446818 AFR_30755 Actinoplanes friuliensis DSM 7358 putative ArsR-family transcriptional regulator YP_008737464.1 6689023 R 1246995 CDS YP_008737465.1 556569040 17446819 6689703..6690116 1 NC_022657.1 COG0456 Acetyltransferases; putative GCN5-related N-acetyltransferase 6690116 17446819 AFR_30760 Actinoplanes friuliensis DSM 7358 putative GCN5-related N-acetyltransferase YP_008737465.1 6689703 D 1246995 CDS YP_008737466.1 556569041 17446820 complement(6690100..6690783) 1 NC_022657.1 hypothetical protein 6690783 17446820 AFR_30765 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737466.1 6690100 R 1246995 CDS YP_008737467.1 556569042 17446821 6690852..6691877 1 NC_022657.1 hypothetical protein 6691877 17446821 AFR_30770 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737467.1 6690852 D 1246995 CDS YP_008737468.1 556569043 17446822 complement(6691890..6692975) 1 NC_022657.1 COG0642 Signal transduction histidine kinase; histidine kinase 6692975 17446822 AFR_30775 Actinoplanes friuliensis DSM 7358 histidine kinase YP_008737468.1 6691890 R 1246995 CDS YP_008737469.1 556569044 17446823 complement(6692972..6693634) 1 NC_022657.1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; two-component system response regulator 6693634 17446823 AFR_30780 Actinoplanes friuliensis DSM 7358 two-component system response regulator YP_008737469.1 6692972 R 1246995 CDS YP_008737470.1 556569045 17446824 6693722..6694468 1 NC_022657.1 COG1131 ABC-type multidrug transport system, ATPase component; lantibiotic transport ATP-binding protein 6694468 17446824 AFR_30785 Actinoplanes friuliensis DSM 7358 lantibiotic transport ATP-binding protein YP_008737470.1 6693722 D 1246995 CDS YP_008737471.1 556569046 17446825 6694465..6695988 1 NC_022657.1 hypothetical protein 6695988 17446825 AFR_30790 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737471.1 6694465 D 1246995 CDS YP_008737472.1 556569047 17446826 6695994..6696725 1 NC_022657.1 hypothetical protein 6696725 17446826 AFR_30795 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737472.1 6695994 D 1246995 CDS YP_008737473.1 556569048 17446827 complement(6696711..6697508) 1 NC_022657.1 COG1091 dTDP-4-dehydrorhamnose reductase; dTDP-4-dehydrorhamnose reductase 6697508 17446827 AFR_30800 Actinoplanes friuliensis DSM 7358 dTDP-4-dehydrorhamnose reductase YP_008737473.1 6696711 R 1246995 CDS YP_008737474.1 556569049 17446828 complement(6697508..6699310) 1 NC_022657.1 COG0173 Aspartyl-tRNA synthetase; aspartyl-tRNA ligase 6699310 aspS 17446828 aspS Actinoplanes friuliensis DSM 7358 aspartyl-tRNA ligase YP_008737474.1 6697508 R 1246995 CDS YP_008737475.1 556569050 17446829 complement(6699411..6700094) 1 NC_022657.1 hypothetical protein 6700094 17446829 AFR_30810 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737475.1 6699411 R 1246995 CDS YP_008737476.1 556569051 17446830 6700350..6700991 1 NC_022657.1 hypothetical protein 6700991 17446830 AFR_30815 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737476.1 6700350 D 1246995 CDS YP_008737477.1 556569052 17446831 complement(6700999..6701646) 1 NC_022657.1 hypothetical protein 6701646 17446831 AFR_30820 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737477.1 6700999 R 1246995 CDS YP_008737478.1 556569053 17446832 6701789..6702850 1 NC_022657.1 COG1522 Transcriptional regulators; transcriptional regulator 6702850 17446832 AFR_30825 Actinoplanes friuliensis DSM 7358 transcriptional regulator YP_008737478.1 6701789 D 1246995 CDS YP_008737479.1 556569054 17446833 complement(6702809..6704338) 1 NC_022657.1 COG0477 Permeases of the major facilitator superfamily; Major facilitator permease 6704338 17446833 AFR_30830 Actinoplanes friuliensis DSM 7358 Major facilitator permease YP_008737479.1 6702809 R 1246995 CDS YP_008737480.1 556569055 17446834 complement(6704460..6705224) 1 NC_022657.1 2-phosphosulfolactate phosphatase 6705224 17446834 AFR_30835 Actinoplanes friuliensis DSM 7358 2-phosphosulfolactate phosphatase YP_008737480.1 6704460 R 1246995 CDS YP_008737481.1 556569056 17446835 complement(6705355..6706338) 1 NC_022657.1 hypothetical protein 6706338 17446835 AFR_30840 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737481.1 6705355 R 1246995 CDS YP_008737482.1 556569057 17446836 complement(6706335..6706697) 1 NC_022657.1 hypothetical protein 6706697 17446836 AFR_30845 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737482.1 6706335 R 1246995 CDS YP_008737483.1 556569058 17446837 complement(6706762..6707229) 1 NC_022657.1 hypothetical protein 6707229 17446837 AFR_30850 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737483.1 6706762 R 1246995 CDS YP_008737484.1 556569059 17446838 6707387..6707884 1 NC_022657.1 COG0457 FOG: TPR repeat; hypothetical protein 6707884 17446838 AFR_30855 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737484.1 6707387 D 1246995 CDS YP_008737485.1 556569060 17446839 complement(6707889..6709457) 1 NC_022657.1 COG3525 N-acetyl-beta-hexosaminidase; beta-hexosaminidase 6709457 17446839 AFR_30860 Actinoplanes friuliensis DSM 7358 beta-hexosaminidase YP_008737485.1 6707889 R 1246995 CDS YP_008737486.1 556569061 17446840 complement(6709454..6710293) 1 NC_022657.1 COG0395 ABC-type sugar transport system, permease component; putative sugar ABC transporter permease 6710293 17446840 AFR_30865 Actinoplanes friuliensis DSM 7358 putative sugar ABC transporter permease YP_008737486.1 6709454 R 1246995 CDS YP_008737487.1 556569062 17446841 complement(6710290..6711168) 1 NC_022657.1 COG1175 ABC-type sugar transport systems, permease components; putative sugar ABC transporter permease 6711168 17446841 AFR_30870 Actinoplanes friuliensis DSM 7358 putative sugar ABC transporter permease YP_008737487.1 6710290 R 1246995 CDS YP_008737488.1 556569063 17446842 complement(6711165..6712427) 1 NC_022657.1 COG1653 ABC-type sugar transport system, periplasmic component; putative sugar ABC transporter substrate-binding protein 6712427 17446842 AFR_30875 Actinoplanes friuliensis DSM 7358 putative sugar ABC transporter substrate-binding protein YP_008737488.1 6711165 R 1246995 CDS YP_008737489.1 556569064 17446843 complement(6712534..6713700) 1 NC_022657.1 COG3616 Predicted amino acid aldolase or racemase; hypothetical protein 6713700 17446843 AFR_30880 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737489.1 6712534 R 1246995 CDS YP_008737490.1 556569065 17446844 6713790..6715097 1 NC_022657.1 hypothetical protein 6715097 17446844 AFR_30885 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737490.1 6713790 D 1246995 CDS YP_008737491.1 556569066 17446845 6715094..6716323 1 NC_022657.1 COG3964 Predicted amidohydrolase; dihydroorotase 6716323 17446845 AFR_30890 Actinoplanes friuliensis DSM 7358 dihydroorotase YP_008737491.1 6715094 D 1246995 CDS YP_008737492.1 556569067 17446846 6716323..6716700 1 NC_022657.1 COG0251 Putative translation initiation inhibitor, yjgF family; putative endoribonuclease L-PSP 6716700 17446846 AFR_30895 Actinoplanes friuliensis DSM 7358 putative endoribonuclease L-PSP YP_008737492.1 6716323 D 1246995 CDS YP_008737493.1 556569068 17446847 complement(6716688..6717437) 1 NC_022657.1 COG1073 Hydrolases of the alpha/beta superfamily; hypothetical protein 6717437 17446847 AFR_30900 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737493.1 6716688 R 1246995 CDS YP_008737494.1 556569069 17446848 6717587..6717889 1 NC_022657.1 COG0831 Urea amidohydrolase (urease) gamma subunit; urease subunit gamma 6717889 ureA 17446848 ureA Actinoplanes friuliensis DSM 7358 urease subunit gamma YP_008737494.1 6717587 D 1246995 CDS YP_008737495.1 556569070 17446849 6717886..6718290 1 NC_022657.1 COG0832 Urea amidohydrolase (urease) beta subunit; urease subunit beta 6718290 ureB 17446849 ureB Actinoplanes friuliensis DSM 7358 urease subunit beta YP_008737495.1 6717886 D 1246995 CDS YP_008737496.1 556569071 17446850 6718287..6720005 1 NC_022657.1 COG0804 Urea amidohydrolase (urease) alpha subunit; urease subunit alpha 6720005 ureC 17446850 ureC Actinoplanes friuliensis DSM 7358 urease subunit alpha YP_008737496.1 6718287 D 1246995 CDS YP_008737497.1 556569072 17446851 6720085..6720717 1 NC_022657.1 COG0830 Urease accessory protein UreF; putative urease accessory protein 6720717 17446851 AFR_30920 Actinoplanes friuliensis DSM 7358 putative urease accessory protein YP_008737497.1 6720085 D 1246995 CDS YP_008737498.1 556569073 17446852 6720707..6721414 1 NC_022657.1 COG0378 Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase; putative urease accessory protein 6721414 17446852 AFR_30925 Actinoplanes friuliensis DSM 7358 putative urease accessory protein YP_008737498.1 6720707 D 1246995 CDS YP_008737499.1 556569074 17446853 6721414..6722214 1 NC_022657.1 COG0829 Urease accessory protein UreH; putative urease accessory protein 6722214 17446853 AFR_30930 Actinoplanes friuliensis DSM 7358 putative urease accessory protein YP_008737499.1 6721414 D 1246995 CDS YP_008737500.1 556569075 17446854 complement(6722184..6723086) 1 NC_022657.1 COG1191 DNA-directed RNA polymerase specialized sigma subunit; putative RNA polymerase sigma factor 6723086 17446854 AFR_30935 Actinoplanes friuliensis DSM 7358 putative RNA polymerase sigma factor YP_008737500.1 6722184 R 1246995 CDS YP_008737501.1 556569076 17446855 complement(6723245..6723502) 1 NC_022657.1 hypothetical protein 6723502 17446855 AFR_30940 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737501.1 6723245 R 1246995 CDS YP_008737502.1 556569077 17446856 complement(6723804..6726062) 1 NC_022657.1 COG0515 Serine/threonine protein kinase; serine/threonine protein kinase 6726062 17446856 AFR_30945 Actinoplanes friuliensis DSM 7358 serine/threonine protein kinase YP_008737502.1 6723804 R 1246995 CDS YP_008737503.1 556569078 17446857 complement(6726614..6729355) 1 NC_022657.1 COG1181 D-alanine-D-alanine ligase and related ATP-grasp enzymes; hypothetical protein 6729355 17446857 AFR_30950 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737503.1 6726614 R 1246995 CDS YP_008737504.1 556569079 17446858 complement(6729352..6730185) 1 NC_022657.1 COG4242 Cyanophycinase and related exopeptidases; cyanophycinase 6730185 17446858 AFR_30955 Actinoplanes friuliensis DSM 7358 cyanophycinase YP_008737504.1 6729352 R 1246995 CDS YP_008737505.1 556569080 17446859 complement(6730229..6731815) 1 NC_022657.1 COG0477 Permeases of the major facilitator superfamily; putative MFS transporter 6731815 17446859 AFR_30960 Actinoplanes friuliensis DSM 7358 putative MFS transporter YP_008737505.1 6730229 R 1246995 CDS YP_008737506.1 556569081 17446860 complement(6731867..6732352) 1 NC_022657.1 COG1733 Predicted transcriptional regulators; putative HxlR-family transcriptional regulator 6732352 17446860 AFR_30965 Actinoplanes friuliensis DSM 7358 putative HxlR-family transcriptional regulator YP_008737506.1 6731867 R 1246995 CDS YP_008737507.1 556569082 17446861 6732409..6732921 1 NC_022657.1 COG2050 Uncharacterized protein, possibly involved in aromatic compounds catabolism; hypothetical protein 6732921 17446861 AFR_30970 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737507.1 6732409 D 1246995 CDS YP_008737508.1 556569083 17446862 complement(6732923..6733615) 1 NC_022657.1 COG0410 ABC-type branched-chain amino acid transport systems, ATPase component; urea ABC transporter ATP-binding protein UrtE 6733615 17446862 AFR_30975 Actinoplanes friuliensis DSM 7358 urea ABC transporter ATP-binding protein UrtE YP_008737508.1 6732923 R 1246995 CDS YP_008737509.1 556569084 17446863 complement(6733617..6734375) 1 NC_022657.1 COG4674 Uncharacterized ABC-type transport system, ATPase component; urea ABC transporter ATP-binding protein UrtD 6734375 17446863 AFR_30980 Actinoplanes friuliensis DSM 7358 urea ABC transporter ATP-binding protein UrtD YP_008737509.1 6733617 R 1246995 CDS YP_008737510.1 556569085 17446864 complement(6734449..6735540) 1 NC_022657.1 COG4177 ABC-type branched-chain amino acid transport system, permease component; urea ABC transporter permease UrtC 6735540 17446864 AFR_30985 Actinoplanes friuliensis DSM 7358 urea ABC transporter permease UrtC YP_008737510.1 6734449 R 1246995 CDS YP_008737511.1 556569086 17446865 complement(6735537..6736418) 1 NC_022657.1 COG0559 Branched-chain amino acid ABC-type transport system, permease components; urea ABC transporter permease UrtB 6736418 17446865 AFR_30990 Actinoplanes friuliensis DSM 7358 urea ABC transporter permease UrtB YP_008737511.1 6735537 R 1246995 CDS YP_008737512.1 556569087 17446866 complement(6736426..6737649) 1 NC_022657.1 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component; urea ABC transporter, urea binding protein 6737649 17446866 AFR_30995 Actinoplanes friuliensis DSM 7358 urea ABC transporter, urea binding protein YP_008737512.1 6736426 R 1246995 CDS YP_008737513.1 556569088 17446867 6737788..6738324 1 NC_022657.1 hypothetical protein 6738324 17446867 AFR_31000 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737513.1 6737788 D 1246995 CDS YP_008737514.1 556569089 17446868 complement(6738321..6739058) 1 NC_022657.1 COG4221 Short-chain alcohol dehydrogenase of unknown specificity; oxidoreductase 6739058 17446868 AFR_31005 Actinoplanes friuliensis DSM 7358 oxidoreductase YP_008737514.1 6738321 R 1246995 CDS YP_008737515.1 556569090 17446869 6739155..6739688 1 NC_022657.1 COG1309 Transcriptional regulator; TetR family transcriptional regulator 6739688 17446869 AFR_31010 Actinoplanes friuliensis DSM 7358 TetR family transcriptional regulator YP_008737515.1 6739155 D 1246995 CDS YP_008737516.1 556569091 17446870 complement(6739780..6741111) 1 NC_022657.1 COG0124 Histidyl-tRNA synthetase; histidyl-tRNA ligase 6741111 hisS 17446870 hisS Actinoplanes friuliensis DSM 7358 histidyl-tRNA ligase YP_008737516.1 6739780 R 1246995 CDS YP_008737517.1 556569092 17446871 complement(6741141..6741839) 1 NC_022657.1 COG0491 Zn-dependent hydrolases, including glyoxylases; putative hydrolase 6741839 17446871 AFR_31020 Actinoplanes friuliensis DSM 7358 putative hydrolase YP_008737517.1 6741141 R 1246995 CDS YP_008737518.1 556569093 17446872 6742005..6742868 1 NC_022657.1 COG0652 Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family; cyclophilin type peptidyl-prolyl cis-trans isomerase 6742868 17446872 AFR_31025 Actinoplanes friuliensis DSM 7358 cyclophilin type peptidyl-prolyl cis-trans isomerase YP_008737518.1 6742005 D 1246995 CDS YP_008737519.1 556569094 17446873 6742934..6743767 1 NC_022657.1 COG0652 Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family; peptidyl-prolyl cis-trans isomerase B 6743767 17446873 AFR_31030 Actinoplanes friuliensis DSM 7358 peptidyl-prolyl cis-trans isomerase B YP_008737519.1 6742934 D 1246995 CDS YP_008737520.1 556569095 17446874 complement(6743812..6746211) 1 NC_022657.1 COG0317 Guanosine polyphosphate pyrophosphohydrolases/synthetases; putative ppGpp synthetase 6746211 17446874 AFR_31035 Actinoplanes friuliensis DSM 7358 putative ppGpp synthetase YP_008737520.1 6743812 R 1246995 CDS YP_008737521.1 556569096 17446875 complement(6746369..6746911) 1 NC_022657.1 COG0503 Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins; adenine phosphoribosyltransferase 6746911 17446875 AFR_31040 Actinoplanes friuliensis DSM 7358 adenine phosphoribosyltransferase YP_008737521.1 6746369 R 1246995 CDS YP_008737522.1 556569097 17446876 complement(6746981..6748156) 1 NC_022657.1 COG0341 Preprotein translocase subunit SecF; Protein-export membrane protein secF 6748156 17446876 AFR_31045 Actinoplanes friuliensis DSM 7358 Protein-export membrane protein secF YP_008737522.1 6746981 R 1246995 CDS YP_008737523.1 556569098 17446877 complement(6748158..6750032) 1 NC_022657.1 COG0342 Preprotein translocase subunit SecD; putative protein-export membrane protein SecD 6750032 17446877 AFR_31050 Actinoplanes friuliensis DSM 7358 putative protein-export membrane protein SecD YP_008737523.1 6748158 R 1246995 CDS YP_008737524.1 556569099 17446878 complement(6750271..6750609) 1 NC_022657.1 COG1862 Preprotein translocase subunit YajC; putative preprotein translocase YajC subunit 6750609 17446878 AFR_31055 Actinoplanes friuliensis DSM 7358 putative preprotein translocase YajC subunit YP_008737524.1 6750271 R 1246995 CDS YP_008737525.1 556569100 17446879 complement(6750782..6751840) 1 NC_022657.1 COG2255 Holliday junction resolvasome, helicase subunit; Holliday junction DNA helicase RuvB 6751840 ruvB 17446879 ruvB Actinoplanes friuliensis DSM 7358 Holliday junction DNA helicase RuvB YP_008737525.1 6750782 R 1246995 CDS YP_008737526.1 556569101 17446880 complement(6751837..6752439) 1 NC_022657.1 COG0632 Holliday junction resolvasome, DNA-binding subunit; Holliday junction DNA helicase RuvA 6752439 ruvA 17446880 ruvA Actinoplanes friuliensis DSM 7358 Holliday junction DNA helicase RuvA YP_008737526.1 6751837 R 1246995 CDS YP_008737527.1 556569102 17446881 complement(6752436..6752975) 1 NC_022657.1 COG0817 Holliday junction resolvasome, endonuclease subunit; Holliday junction resolvase 6752975 17446881 AFR_31070 Actinoplanes friuliensis DSM 7358 Holliday junction resolvase YP_008737527.1 6752436 R 1246995 CDS YP_008737528.1 556569103 17446882 6754099..6755052 1 NC_022657.1 hypothetical protein 6755052 17446882 AFR_31075 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737528.1 6754099 D 1246995 CDS YP_008737529.1 556569104 17446883 complement(6755247..6756002) 1 NC_022657.1 COG0217 Uncharacterized conserved protein; hypothetical protein 6756002 17446883 AFR_31080 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737529.1 6755247 R 1246995 CDS YP_008737530.1 556569105 17446884 complement(6756027..6756644) 1 NC_022657.1 COG0311 Predicted glutamine amidotransferase involved in pyridoxine biosynthesis; putative glutamine amidotransferase 6756644 17446884 AFR_31085 Actinoplanes friuliensis DSM 7358 putative glutamine amidotransferase YP_008737530.1 6756027 R 1246995 CDS YP_008737531.1 556569106 17446885 complement(6756717..6757613) 1 NC_022657.1 COG0214 Pyridoxine biosynthesis enzyme; pyridoxal biosynthesis lyase PdxS 6757613 17446885 AFR_31090 Actinoplanes friuliensis DSM 7358 pyridoxal biosynthesis lyase PdxS YP_008737531.1 6756717 R 1246995 CDS YP_008737532.1 556569107 17446886 complement(6757874..6758143) 1 NC_022657.1 COG1987 Flagellar biosynthesis pathway, component FliQ; Flagellar biosynthetic protein fliQ 6758143 17446886 AFR_31095 Actinoplanes friuliensis DSM 7358 Flagellar biosynthetic protein fliQ YP_008737532.1 6757874 R 1246995 CDS YP_008737533.1 556569108 17446887 complement(6758229..6758735) 1 NC_022657.1 hypothetical protein 6758735 17446887 AFR_31100 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737533.1 6758229 R 1246995 CDS YP_008737534.1 556569109 17446888 complement(6758797..6759951) 1 NC_022657.1 COG0438 Glycosyltransferase; putative glycosyltransferase 6759951 17446888 AFR_31105 Actinoplanes friuliensis DSM 7358 putative glycosyltransferase YP_008737534.1 6758797 R 1246995 CDS YP_008737535.1 556569110 17446889 complement(6759965..6760870) 1 NC_022657.1 COG1560 Lauroyl/myristoyl acyltransferase; lipid A biosynthesis lauroyl acyltransferase 6760870 17446889 AFR_31110 Actinoplanes friuliensis DSM 7358 lipid A biosynthesis lauroyl acyltransferase YP_008737535.1 6759965 R 1246995 CDS YP_008737536.1 556569111 17446890 complement(6760867..6761499) 1 NC_022657.1 COG0558 Phosphatidylglycerophosphate synthase; CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 6761499 17446890 AFR_31115 Actinoplanes friuliensis DSM 7358 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase YP_008737536.1 6760867 R 1246995 CDS YP_008737537.1 556569112 17446891 6761727..6763877 1 NC_022657.1 COG0480 Translation elongation factors (GTPases); elongation factor G 6763877 17446891 AFR_31120 Actinoplanes friuliensis DSM 7358 elongation factor G YP_008737537.1 6761727 D 1246995 CDS YP_008737538.1 556569113 17446892 complement(6763879..6765069) 1 NC_022657.1 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases; 3-(3-hydroxy-phenyl)propionate/3- hydroxycinnamic acid hydroxylase 6765069 17446892 AFR_31125 Actinoplanes friuliensis DSM 7358 3-(3-hydroxy-phenyl)propionate/3- hydroxycinnamic acid hydroxylase YP_008737538.1 6763879 R 1246995 CDS YP_008737539.1 556569114 17446893 6765124..6765753 1 NC_022657.1 COG1309 Transcriptional regulator; putative TetR-family transcriptional regulator 6765753 17446893 AFR_31130 Actinoplanes friuliensis DSM 7358 putative TetR-family transcriptional regulator YP_008737539.1 6765124 D 1246995 CDS YP_008737540.1 556569115 17446894 6765717..6767648 1 NC_022657.1 COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain; diguanylate cyclase 6767648 17446894 AFR_31135 Actinoplanes friuliensis DSM 7358 diguanylate cyclase YP_008737540.1 6765717 D 1246995 CDS YP_008737541.1 556569116 17446895 6767651..6768916 1 NC_022657.1 COG1653 ABC-type sugar transport system, periplasmic component; family 1 extracellular solute-binding protein 6768916 17446895 AFR_31140 Actinoplanes friuliensis DSM 7358 family 1 extracellular solute-binding protein YP_008737541.1 6767651 D 1246995 CDS YP_008737542.1 556569117 17446896 complement(6768913..6769446) 1 NC_022657.1 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases; histidine triad (hit) protein 6769446 17446896 AFR_31145 Actinoplanes friuliensis DSM 7358 histidine triad (hit) protein YP_008737542.1 6768913 R 1246995 CDS YP_008737543.1 556569118 17446897 6769576..6770511 1 NC_022657.1 hypothetical protein 6770511 17446897 AFR_31150 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737543.1 6769576 D 1246995 CDS YP_008737544.1 556569119 17446898 6770574..6771059 1 NC_022657.1 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; putative RNA polymerase ECF-subfamily sigma factor 6771059 17446898 AFR_31155 Actinoplanes friuliensis DSM 7358 putative RNA polymerase ECF-subfamily sigma factor YP_008737544.1 6770574 D 1246995 CDS YP_008737545.1 556569120 17446899 6771056..6772129 1 NC_022657.1 hypothetical protein 6772129 17446899 AFR_31160 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737545.1 6771056 D 1246995 CDS YP_008737546.1 556569121 17446900 complement(6772173..6774167) 1 NC_022657.1 COG0441 Threonyl-tRNA synthetase; threonyl-tRNA ligase 6774167 thrS 17446900 thrS Actinoplanes friuliensis DSM 7358 threonyl-tRNA ligase YP_008737546.1 6772173 R 1246995 CDS YP_008737547.1 556569122 17446901 complement(6774225..6775184) 1 NC_022657.1 COG1397 ADP-ribosylglycohydrolase; putative ADP-ribosylglycohydrolase 6775184 17446901 AFR_31170 Actinoplanes friuliensis DSM 7358 putative ADP-ribosylglycohydrolase YP_008737547.1 6774225 R 1246995 CDS YP_008737548.1 556569123 17446902 6775255..6775944 1 NC_022657.1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; putative two-component system response regulator 6775944 17446902 AFR_31175 Actinoplanes friuliensis DSM 7358 putative two-component system response regulator YP_008737548.1 6775255 D 1246995 CDS YP_008737549.1 556569124 17446903 6776022..6777380 1 NC_022657.1 COG0642 Signal transduction histidine kinase; putative two-component system sensor kinase 6777380 17446903 AFR_31180 Actinoplanes friuliensis DSM 7358 putative two-component system sensor kinase YP_008737549.1 6776022 D 1246995 CDS YP_008737550.1 556569125 17446904 6777625..6779829 1 NC_022657.1 hypothetical protein 6779829 17446904 AFR_31185 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737550.1 6777625 D 1246995 CDS YP_008737551.1 556569126 17446905 6779852..6779998 1 NC_022657.1 hypothetical protein 6779998 17446905 AFR_31190 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737551.1 6779852 D 1246995 CDS YP_008737552.1 556569127 17446906 complement(6779995..6781014) 1 NC_022657.1 COG1816 Adenosine deaminase; adenosine deaminase 6781014 17446906 AFR_31195 Actinoplanes friuliensis DSM 7358 adenosine deaminase YP_008737552.1 6779995 R 1246995 CDS YP_008737553.1 556569128 17446907 complement(6781011..6781796) 1 NC_022657.1 COG4106 Trans-aconitate methyltransferase; trans-aconitate 2-methyltransferase 6781796 17446907 AFR_31200 Actinoplanes friuliensis DSM 7358 trans-aconitate 2-methyltransferase YP_008737553.1 6781011 R 1246995 CDS YP_008737554.1 556569129 17446908 6781862..6782839 1 NC_022657.1 COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases); putative aldo/keto reductase 6782839 17446908 AFR_31205 Actinoplanes friuliensis DSM 7358 putative aldo/keto reductase YP_008737554.1 6781862 D 1246995 CDS YP_008737555.1 556569130 17446909 6782850..6783050 1 NC_022657.1 hypothetical protein 6783050 17446909 AFR_31210 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737555.1 6782850 D 1246995 CDS YP_008737556.1 556569131 17446910 complement(6783153..6783356) 1 NC_022657.1 COG1278 Cold shock proteins; cold-shock DNA-binding domain-containing protein 6783356 17446910 AFR_31215 Actinoplanes friuliensis DSM 7358 cold-shock DNA-binding domain-containing protein YP_008737556.1 6783153 R 1246995 CDS YP_008737557.1 556569132 17446911 complement(6783619..6783891) 1 NC_022657.1 hypothetical protein 6783891 17446911 AFR_31220 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737557.1 6783619 R 1246995 CDS YP_008737558.1 556569133 17446912 complement(6783888..6784361) 1 NC_022657.1 hypothetical protein 6784361 17446912 AFR_31225 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737558.1 6783888 R 1246995 CDS YP_008737559.1 556569134 17446913 complement(6784358..6784792) 1 NC_022657.1 hypothetical protein 6784792 17446913 AFR_31230 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737559.1 6784358 R 1246995 CDS YP_008737560.1 556569135 17446914 complement(6784868..6786043) 1 NC_022657.1 COG0668 Small-conductance mechanosensitive channel; putative mechanosensitive ion channel 6786043 17446914 AFR_31235 Actinoplanes friuliensis DSM 7358 putative mechanosensitive ion channel YP_008737560.1 6784868 R 1246995 CDS YP_008737561.1 556569136 17446915 complement(6786156..6786974) 1 NC_022657.1 hypothetical protein 6786974 17446915 AFR_31240 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737561.1 6786156 R 1246995 CDS YP_008737562.1 556569137 17446916 complement(6787036..6787359) 1 NC_022657.1 hypothetical protein 6787359 17446916 AFR_31245 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737562.1 6787036 R 1246995 CDS YP_008737563.1 556569138 17446917 6787406..6787687 1 NC_022657.1 COG2388 Predicted acetyltransferase; hypothetical protein 6787687 17446917 AFR_31250 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737563.1 6787406 D 1246995 CDS YP_008737564.1 556569139 17446918 complement(6787692..6789200) 1 NC_022657.1 COG1472 Beta-glucosidase-related glycosidases; beta-N-acetylhexosaminidase 6789200 17446918 AFR_31255 Actinoplanes friuliensis DSM 7358 beta-N-acetylhexosaminidase YP_008737564.1 6787692 R 1246995 CDS YP_008737565.1 556569140 17446919 6789471..6789599 1 NC_022657.1 hypothetical protein 6789599 17446919 AFR_31260 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737565.1 6789471 D 1246995 CDS YP_008737566.1 556569141 17446920 6789619..6790569 1 NC_022657.1 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases; putative luciferase-like monooxygenase 6790569 17446920 AFR_31265 Actinoplanes friuliensis DSM 7358 putative luciferase-like monooxygenase YP_008737566.1 6789619 D 1246995 CDS YP_008737567.1 556569142 17446921 6790610..6792256 1 NC_022657.1 COG0514 Superfamily II DNA helicase; putative ATP-dependent DNA helicase 6792256 17446921 AFR_31270 Actinoplanes friuliensis DSM 7358 putative ATP-dependent DNA helicase YP_008737567.1 6790610 D 1246995 CDS YP_008737568.1 556569143 17446922 6792264..6792767 1 NC_022657.1 hypothetical protein 6792767 17446922 AFR_31275 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737568.1 6792264 D 1246995 CDS YP_008737569.1 556569144 17446923 complement(6792795..6793331) 1 NC_022657.1 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins; hypothetical protein 6793331 17446923 AFR_31280 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737569.1 6792795 R 1246995 CDS YP_008737570.1 556569145 17446924 6793368..6794210 1 NC_022657.1 COG2207 AraC-type DNA-binding domain-containing proteins; putative AraC-family transcriptional regulator 6794210 17446924 AFR_31285 Actinoplanes friuliensis DSM 7358 putative AraC-family transcriptional regulator YP_008737570.1 6793368 D 1246995 CDS YP_008737571.1 556569146 17446925 6794203..6794625 1 NC_022657.1 COG2764 Uncharacterized protein conserved in bacteria; hypothetical protein 6794625 17446925 AFR_31290 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737571.1 6794203 D 1246995 CDS YP_008737572.1 556569147 17446926 complement(6794595..6795170) 1 NC_022657.1 COG0262 Dihydrofolate reductase; hypothetical protein 6795170 17446926 AFR_31295 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737572.1 6794595 R 1246995 CDS YP_008737573.1 556569148 17446927 complement(6795167..6795790) 1 NC_022657.1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; putative two-component system response regulator 6795790 17446927 AFR_31300 Actinoplanes friuliensis DSM 7358 putative two-component system response regulator YP_008737573.1 6795167 R 1246995 CDS YP_008737574.1 556569149 17446928 complement(6795787..6797058) 1 NC_022657.1 COG4585 Signal transduction histidine kinase; putative two-component system sensor kinase 6797058 17446928 AFR_31305 Actinoplanes friuliensis DSM 7358 putative two-component system sensor kinase YP_008737574.1 6795787 R 1246995 CDS YP_008737575.1 556569150 17446929 complement(6797067..6797807) 1 NC_022657.1 COG0842 ABC-type multidrug transport system, permease component; Putative pleiotropic drug resistance protein 7 6797807 17446929 AFR_31310 Actinoplanes friuliensis DSM 7358 Putative pleiotropic drug resistance protein 7 YP_008737575.1 6797067 R 1246995 CDS YP_008737576.1 556569151 17446930 complement(6797807..6798715) 1 NC_022657.1 COG1131 ABC-type multidrug transport system, ATPase component; spermidine/putrescine import ATP-binding protein potA 6798715 17446930 AFR_31315 Actinoplanes friuliensis DSM 7358 spermidine/putrescine import ATP-binding protein potA YP_008737576.1 6797807 R 1246995 CDS YP_008737577.1 556569152 17446931 complement(6798798..6799994) 1 NC_022657.1 COG0438 Glycosyltransferase; group 1 glycosyl transferase 6799994 17446931 AFR_31320 Actinoplanes friuliensis DSM 7358 group 1 glycosyl transferase YP_008737577.1 6798798 R 1246995 CDS YP_008737578.1 556569153 17446932 6800245..6800565 1 NC_022657.1 hypothetical protein 6800565 17446932 AFR_31325 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737578.1 6800245 D 1246995 CDS YP_008737579.1 556569154 17446933 6800562..6801569 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); short chain dehydrogenase 6801569 17446933 AFR_31330 Actinoplanes friuliensis DSM 7358 short chain dehydrogenase YP_008737579.1 6800562 D 1246995 CDS YP_008737580.1 556569155 17446934 complement(6801678..6803267) 1 NC_022657.1 COG1233 Phytoene dehydrogenase and related proteins; putative dehydrogenase 6803267 17446934 AFR_31335 Actinoplanes friuliensis DSM 7358 putative dehydrogenase YP_008737580.1 6801678 R 1246995 CDS YP_008737581.1 556569156 17446935 6803370..6804326 1 NC_022657.1 COG1295 Predicted membrane protein; ribonuclease bn 6804326 17446935 AFR_31340 Actinoplanes friuliensis DSM 7358 ribonuclease bn YP_008737581.1 6803370 D 1246995 CDS YP_008737582.1 556569157 17446936 6804392..6804856 1 NC_022657.1 COG5637 Predicted integral membrane protein; putative polyketide cyclase/dehydrase 6804856 17446936 AFR_31345 Actinoplanes friuliensis DSM 7358 putative polyketide cyclase/dehydrase YP_008737582.1 6804392 D 1246995 CDS YP_008737583.1 556569158 17446937 6804928..6805143 1 NC_022657.1 hypothetical protein 6805143 17446937 AFR_31350 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737583.1 6804928 D 1246995 CDS YP_008737584.1 556569159 17446938 complement(6805166..6805849) 1 NC_022657.1 hypothetical protein 6805849 17446938 AFR_31355 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737584.1 6805166 R 1246995 CDS YP_008737585.1 556569160 17446939 6805992..6806201 1 NC_022657.1 hypothetical protein 6806201 17446939 AFR_31360 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737585.1 6805992 D 1246995 CDS YP_008737586.1 556569161 17446940 complement(6806204..6806632) 1 NC_022657.1 hypothetical protein 6806632 17446940 AFR_31365 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737586.1 6806204 R 1246995 CDS YP_008737587.1 556569162 17446941 6806743..6807099 1 NC_022657.1 hypothetical protein 6807099 17446941 AFR_31370 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737587.1 6806743 D 1246995 CDS YP_008737588.1 556569163 17446942 complement(6807178..6808521) 1 NC_022657.1 TM helix repeat-containing protein 6808521 17446942 AFR_31375 Actinoplanes friuliensis DSM 7358 TM helix repeat-containing protein YP_008737588.1 6807178 R 1246995 CDS YP_008737589.1 556569164 17446943 6810188..6812179 1 NC_022657.1 COG2202 FOG: PAS/PAC domain; putative magnesium/manganese-dependent protein phosphatase with GAF domain 6812179 17446943 AFR_31380 Actinoplanes friuliensis DSM 7358 putative magnesium/manganese-dependent protein phosphatase with GAF domain YP_008737589.1 6810188 D 1246995 CDS YP_008737590.1 556569165 17446944 complement(6812181..6812978) 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); oxidoreductase 6812978 17446944 AFR_31385 Actinoplanes friuliensis DSM 7358 oxidoreductase YP_008737590.1 6812181 R 1246995 CDS YP_008737591.1 556569166 17446945 6813060..6814328 1 NC_022657.1 COG0025 NhaP-type Na+/H+ and K+/H+ antiporters; putative sodium/proton antiporter 6814328 17446945 AFR_31390 Actinoplanes friuliensis DSM 7358 putative sodium/proton antiporter YP_008737591.1 6813060 D 1246995 CDS YP_008737592.1 556569167 17446946 6814486..6815268 1 NC_022657.1 COG3324 Predicted enzyme related to lactoylglutathione lyase; hypothetical protein 6815268 17446946 AFR_31395 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737592.1 6814486 D 1246995 CDS YP_008737593.1 556569168 17446947 6815305..6815514 1 NC_022657.1 hypothetical protein 6815514 17446947 AFR_31400 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737593.1 6815305 D 1246995 CDS YP_008737594.1 556569169 17446948 6815613..6815849 1 NC_022657.1 hypothetical protein 6815849 17446948 AFR_31405 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737594.1 6815613 D 1246995 CDS YP_008737595.1 556569170 17446949 6815852..6816466 1 NC_022657.1 COG0542 ATPases with chaperone activity, ATP-binding subunit; clpA-like ATP-dependent Clp protease 6816466 17446949 AFR_31410 Actinoplanes friuliensis DSM 7358 clpA-like ATP-dependent Clp protease YP_008737595.1 6815852 D 1246995 CDS YP_008737596.1 556569171 17446950 complement(6816470..6816763) 1 NC_022657.1 hypothetical protein 6816763 17446950 AFR_31415 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737596.1 6816470 R 1246995 CDS YP_008737597.1 556569172 17446951 6817074..6817496 1 NC_022657.1 hypothetical protein 6817496 17446951 AFR_31420 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737597.1 6817074 D 1246995 CDS YP_008737598.1 556569173 17446952 6817500..6818186 1 NC_022657.1 COG1708 Predicted nucleotidyltransferases; hypothetical protein 6818186 17446952 AFR_31425 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737598.1 6817500 D 1246995 CDS YP_008737599.1 556569174 17446953 complement(6818177..6819340) 1 NC_022657.1 COG1940 Transcriptional regulator/sugar kinase; ROK family protein 6819340 17446953 AFR_31430 Actinoplanes friuliensis DSM 7358 ROK family protein YP_008737599.1 6818177 R 1246995 CDS YP_008737600.1 556569175 17446954 6819391..6819996 1 NC_022657.1 COG0637 Predicted phosphatase/phosphohexomutase; HAD-superfamily hydrolase 6819996 17446954 AFR_31435 Actinoplanes friuliensis DSM 7358 HAD-superfamily hydrolase YP_008737600.1 6819391 D 1246995 CDS YP_008737601.1 556569176 17446955 6819998..6821098 1 NC_022657.1 COG0136 Aspartate-semialdehyde dehydrogenase; hypothetical protein 6821098 17446955 AFR_31440 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737601.1 6819998 D 1246995 CDS YP_008737602.1 556569177 17446956 6821143..6821619 1 NC_022657.1 COG1846 Transcriptional regulators; putative MarR-family transcriptional regulator 6821619 17446956 AFR_31445 Actinoplanes friuliensis DSM 7358 putative MarR-family transcriptional regulator YP_008737602.1 6821143 D 1246995 CDS YP_008737603.1 556569178 17446957 6821629..6822600 1 NC_022657.1 COG1741 Pirin-related protein; Pirin-like protein 6822600 17446957 AFR_31450 Actinoplanes friuliensis DSM 7358 Pirin-like protein YP_008737603.1 6821629 D 1246995 CDS YP_008737604.1 556569179 17446958 complement(6822566..6823360) 1 NC_022657.1 COG2910 Putative NADH-flavin reductase; hypothetical protein 6823360 17446958 AFR_31455 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737604.1 6822566 R 1246995 CDS YP_008737605.1 556569180 17446959 6824394..6824750 1 NC_022657.1 COG1733 Predicted transcriptional regulators; putative HxlR-family transcriptional regulator 6824750 17446959 AFR_31460 Actinoplanes friuliensis DSM 7358 putative HxlR-family transcriptional regulator YP_008737605.1 6824394 D 1246995 CDS YP_008737606.1 556569181 17446960 complement(6824758..6826071) 1 NC_022657.1 hypothetical protein 6826071 17446960 AFR_31465 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737606.1 6824758 R 1246995 CDS YP_008737607.1 556569182 17446961 6826366..6827943 1 NC_022657.1 COG1502 Phosphatidylserine/phosphatidylglycerophosphate/cardiolipi n synthases and related enzymes; putative phospholipase 6827943 17446961 AFR_31470 Actinoplanes friuliensis DSM 7358 putative phospholipase YP_008737607.1 6826366 D 1246995 CDS YP_008737608.1 556569183 17446962 6828014..6829309 1 NC_022657.1 COG4585 Signal transduction histidine kinase; histidine kinase dimerization and phosphoacceptor region 6829309 17446962 AFR_31475 Actinoplanes friuliensis DSM 7358 histidine kinase dimerization and phosphoacceptor region YP_008737608.1 6828014 D 1246995 CDS YP_008737609.1 556569184 17446963 6829297..6829950 1 NC_022657.1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; two component LuxR family transcriptional regulator 6829950 17446963 AFR_31480 Actinoplanes friuliensis DSM 7358 two component LuxR family transcriptional regulator YP_008737609.1 6829297 D 1246995 CDS YP_008737610.1 556569185 17446964 complement(6829947..6831041) 1 NC_022657.1 COG2518 Protein-L-isoaspartate carboxylmethyltransferase; protein-L-isoaspartate(D-aspartate) O-methyltransferase 6831041 17446964 AFR_31485 Actinoplanes friuliensis DSM 7358 protein-L-isoaspartate(D-aspartate) O-methyltransferase YP_008737610.1 6829947 R 1246995 CDS YP_008737611.1 556569186 17446965 complement(6831034..6832197) 1 NC_022657.1 aminoglycoside phosphotransferase 6832197 17446965 AFR_31490 Actinoplanes friuliensis DSM 7358 aminoglycoside phosphotransferase YP_008737611.1 6831034 R 1246995 CDS YP_008737612.1 556569187 17446966 6832272..6833057 1 NC_022657.1 COG1305 Transglutaminase-like enzymes, putative cysteine proteases; transglutaminase/protease 6833057 17446966 AFR_31495 Actinoplanes friuliensis DSM 7358 transglutaminase/protease YP_008737612.1 6832272 D 1246995 CDS YP_008737613.1 556569188 17446967 complement(6833065..6834066) 1 NC_022657.1 COG4266 Allantoicase; allantoicase 6834066 17446967 AFR_31500 Actinoplanes friuliensis DSM 7358 allantoicase YP_008737613.1 6833065 R 1246995 CDS YP_008737614.1 556569189 17446968 complement(6834066..6835379) 1 NC_022657.1 COG0044 Dihydroorotase and related cyclic amidohydrolases; putative allantoinase 6835379 17446968 AFR_31505 Actinoplanes friuliensis DSM 7358 putative allantoinase YP_008737614.1 6834066 R 1246995 CDS YP_008737615.1 556569190 17446969 6835521..6836054 1 NC_022657.1 hypothetical protein 6836054 17446969 AFR_31510 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737615.1 6835521 D 1246995 CDS YP_008737616.1 556569191 17446970 complement(6836064..6837212) 1 NC_022657.1 hypothetical protein 6837212 17446970 AFR_31515 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737616.1 6836064 R 1246995 CDS YP_008737617.1 556569192 17446971 complement(6837215..6838762) 1 NC_022657.1 COG2225 Malate synthase; putative malate synthase 6838762 17446971 AFR_31520 Actinoplanes friuliensis DSM 7358 putative malate synthase YP_008737617.1 6837215 R 1246995 CDS YP_008737618.1 556569193 17446972 complement(6838953..6840440) 1 NC_022657.1 hypothetical protein 6840440 17446972 AFR_31525 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737618.1 6838953 R 1246995 CDS YP_008737619.1 556569194 17446973 complement(6840621..6841973) 1 NC_022657.1 COG0402 Cytosine deaminase and related metal-dependent hydrolases; hydroxydechloroatrazine ethylaminohydrolase 6841973 17446973 AFR_31530 Actinoplanes friuliensis DSM 7358 hydroxydechloroatrazine ethylaminohydrolase YP_008737619.1 6840621 R 1246995 CDS YP_008737620.1 556569195 17446974 complement(6841970..6842830) 1 NC_022657.1 COG3648 Uricase (urate oxidase); urate oxidase 6842830 17446974 AFR_31535 Actinoplanes friuliensis DSM 7358 urate oxidase YP_008737620.1 6841970 R 1246995 CDS YP_008737621.1 556569196 17446975 complement(6842837..6843199) 1 NC_022657.1 COG2351 Transthyretin-like protein; hydroxyisourate hydrolase 6843199 17446975 AFR_31540 Actinoplanes friuliensis DSM 7358 hydroxyisourate hydrolase YP_008737621.1 6842837 R 1246995 CDS YP_008737622.1 556569197 17446976 complement(6843186..6843695) 1 NC_022657.1 COG3195 Uncharacterized protein conserved in bacteria; putative OHCU decarboxylase 6843695 17446976 AFR_31545 Actinoplanes friuliensis DSM 7358 putative OHCU decarboxylase YP_008737622.1 6843186 R 1246995 CDS YP_008737623.1 556569198 17446977 6843825..6846290 1 NC_022657.1 COG1643 HrpA-like helicases; ATP-dependent helicase HrpB 6846290 17446977 AFR_31550 Actinoplanes friuliensis DSM 7358 ATP-dependent helicase HrpB YP_008737623.1 6843825 D 1246995 CDS YP_008737624.1 556569199 17446978 complement(6847813..6850122) 1 NC_022657.1 COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain; diguanylate cyclase 6850122 17446978 AFR_31555 Actinoplanes friuliensis DSM 7358 diguanylate cyclase YP_008737624.1 6847813 R 1246995 CDS YP_008737625.1 556569200 17446979 complement(6850219..6850941) 1 NC_022657.1 COG0631 Serine/threonine protein phosphatase; protein phosphatase 6850941 17446979 AFR_31560 Actinoplanes friuliensis DSM 7358 protein phosphatase YP_008737625.1 6850219 R 1246995 CDS YP_008737626.1 556569201 17446980 complement(6851033..6852061) 1 NC_022657.1 hypothetical protein 6852061 17446980 AFR_31565 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737626.1 6851033 R 1246995 CDS YP_008737627.1 556569202 17446981 complement(6852058..6853167) 1 NC_022657.1 COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; Membrane-bound lytic murein transglycosylase F 6853167 17446981 AFR_31570 Actinoplanes friuliensis DSM 7358 Membrane-bound lytic murein transglycosylase F YP_008737627.1 6852058 R 1246995 CDS YP_008737628.1 556569203 17446982 complement(6853223..6853612) 1 NC_022657.1 COG0759 Uncharacterized conserved protein; hypothetical protein 6853612 17446982 AFR_31575 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737628.1 6853223 R 1246995 CDS YP_008737629.1 556569204 17446983 6853660..6854400 1 NC_022657.1 hypothetical protein 6854400 17446983 AFR_31580 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737629.1 6853660 D 1246995 CDS YP_008737630.1 556569205 17446984 complement(6854397..6856130) 1 NC_022657.1 COG0296 1,4-alpha-glucan branching enzyme; maltooligosyltrehalose trehalohydrolase 6856130 17446984 AFR_31585 Actinoplanes friuliensis DSM 7358 maltooligosyltrehalose trehalohydrolase YP_008737630.1 6854397 R 1246995 CDS YP_008737631.1 556569206 17446985 complement(6856127..6858397) 1 NC_022657.1 COG3280 Maltooligosyl trehalose synthase; maltooligosyl trehalose synthase 6858397 17446985 AFR_31590 Actinoplanes friuliensis DSM 7358 maltooligosyl trehalose synthase YP_008737631.1 6856127 R 1246995 CDS YP_008737632.1 556569207 17446986 complement(6858399..6860510) 1 NC_022657.1 COG1523 Type II secretory pathway, pullulanase PulA and related glycosidases; glycogen operon protein GlgX 6860510 17446986 AFR_31595 Actinoplanes friuliensis DSM 7358 glycogen operon protein GlgX YP_008737632.1 6858399 R 1246995 CDS YP_008737633.1 556569208 17446987 complement(6860804..6861067) 1 NC_022657.1 hypothetical protein 6861067 17446987 AFR_31600 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737633.1 6860804 R 1246995 CDS YP_008737634.1 556569209 17446988 complement(6861064..6862638) 1 NC_022657.1 COG0025 NhaP-type Na+/H+ and K+/H+ antiporters; putative sodium/proton antiporter 6862638 17446988 AFR_31605 Actinoplanes friuliensis DSM 7358 putative sodium/proton antiporter YP_008737634.1 6861064 R 1246995 CDS YP_008737635.1 556569210 17446989 6862802..6863791 1 NC_022657.1 COG0332 3-oxoacyl-[acyl-carrier-protein] synthase III; putative 3-oxoacyl-ACP synthase III 6863791 17446989 AFR_31610 Actinoplanes friuliensis DSM 7358 putative 3-oxoacyl-ACP synthase III YP_008737635.1 6862802 D 1246995 CDS YP_008737636.1 556569211 17446990 6863788..6864519 1 NC_022657.1 COG0463 Glycosyltransferases involved in cell wall biogenesis; putative glycosyltransferase 6864519 17446990 AFR_31615 Actinoplanes friuliensis DSM 7358 putative glycosyltransferase YP_008737636.1 6863788 D 1246995 CDS YP_008737637.1 556569212 17446991 6864519..6865970 1 NC_022657.1 COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II; AMP-dependent synthetase and ligase 6865970 17446991 AFR_31620 Actinoplanes friuliensis DSM 7358 AMP-dependent synthetase and ligase YP_008737637.1 6864519 D 1246995 CDS YP_008737638.1 556569213 17446992 6865982..6866701 1 NC_022657.1 putative glycosyltransferase 6866701 17446992 AFR_31625 Actinoplanes friuliensis DSM 7358 putative glycosyltransferase YP_008737638.1 6865982 D 1246995 CDS YP_008737639.1 556569214 17446993 6866698..6867810 1 NC_022657.1 cytochrome P450 6867810 17446993 AFR_31630 Actinoplanes friuliensis DSM 7358 cytochrome P450 YP_008737639.1 6866698 D 1246995 CDS YP_008737640.1 556569215 17446994 6867894..6868670 1 NC_022657.1 COG0451 Nucleoside-diphosphate-sugar epimerases; UDP-N-acetylglucosamine 4-epimerase 6868670 17446994 AFR_31635 Actinoplanes friuliensis DSM 7358 UDP-N-acetylglucosamine 4-epimerase YP_008737640.1 6867894 D 1246995 CDS YP_008737641.1 556569216 17446995 complement(6868640..6869239) 1 NC_022657.1 hypothetical protein 6869239 17446995 AFR_31640 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737641.1 6868640 R 1246995 CDS YP_008737642.1 556569217 17446996 complement(6869299..6869904) 1 NC_022657.1 hypothetical protein 6869904 17446996 AFR_31645 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737642.1 6869299 R 1246995 CDS YP_008737643.1 556569218 17446997 6870180..6872549 1 NC_022657.1 COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain; putative signaling protein 6872549 17446997 AFR_31650 Actinoplanes friuliensis DSM 7358 putative signaling protein YP_008737643.1 6870180 D 1246995 CDS YP_008737644.1 556569219 17446998 6872655..6874271 1 NC_022657.1 COG0840 Methyl-accepting chemotaxis protein; putative methyl-accepting chemotaxis protein 6874271 17446998 AFR_31655 Actinoplanes friuliensis DSM 7358 putative methyl-accepting chemotaxis protein YP_008737644.1 6872655 D 1246995 CDS YP_008737645.1 556569220 17446999 6874335..6875294 1 NC_022657.1 hypothetical protein 6875294 17446999 AFR_31660 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737645.1 6874335 D 1246995 CDS YP_008737646.1 556569221 17447000 complement(6875298..6877550) 1 NC_022657.1 COG4870 Cysteine protease; cell surface receptor IPT/TIG domain-containing protein 6877550 17447000 AFR_31665 Actinoplanes friuliensis DSM 7358 cell surface receptor IPT/TIG domain-containing protein YP_008737646.1 6875298 R 1246995 CDS YP_008737647.1 556569222 17447001 6877724..6879277 1 NC_022657.1 COG0840 Methyl-accepting chemotaxis protein; Laminin subunit beta-2 6879277 17447001 AFR_31670 Actinoplanes friuliensis DSM 7358 Laminin subunit beta-2 YP_008737647.1 6877724 D 1246995 CDS YP_008737648.1 556569223 17447002 complement(6879274..6880011) 1 NC_022657.1 COG0627 Predicted esterase; putative esterase 6880011 17447002 AFR_31675 Actinoplanes friuliensis DSM 7358 putative esterase YP_008737648.1 6879274 R 1246995 CDS YP_008737649.1 556569224 17447003 6880148..6880780 1 NC_022657.1 hypothetical protein 6880780 17447003 AFR_31680 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737649.1 6880148 D 1246995 CDS YP_008737650.1 556569225 17447004 6880913..6881896 1 NC_022657.1 COG1506 Dipeptidyl aminopeptidases/acylaminoacyl-peptidases; hypothetical protein 6881896 17447004 AFR_31685 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737650.1 6880913 D 1246995 CDS YP_008737651.1 556569226 17447005 6882366..6882779 1 NC_022657.1 RNA polymerase sigma factor rpoD 6882779 17447005 AFR_31690 Actinoplanes friuliensis DSM 7358 RNA polymerase sigma factor rpoD YP_008737651.1 6882366 D 1246995 CDS YP_008737652.1 556569227 17447006 6883031..6883654 1 NC_022657.1 COG0220 Predicted S-adenosylmethionine-dependent methyltransferase; putative methyltransferase 6883654 17447006 AFR_31695 Actinoplanes friuliensis DSM 7358 putative methyltransferase YP_008737652.1 6883031 D 1246995 CDS YP_008737653.1 556569228 17447007 6883871..6885898 1 NC_022657.1 COG5002 Signal transduction histidine kinase; putative multi-sensor signal transduction histidine kinase 6885898 17447007 AFR_31700 Actinoplanes friuliensis DSM 7358 putative multi-sensor signal transduction histidine kinase YP_008737653.1 6883871 D 1246995 CDS YP_008737654.1 556569229 17447008 6885958..6887361 1 NC_022657.1 COG3391 Uncharacterized conserved protein; Selenium-binding protein 1 6887361 17447008 AFR_31705 Actinoplanes friuliensis DSM 7358 Selenium-binding protein 1 YP_008737654.1 6885958 D 1246995 CDS YP_008737655.1 556569230 17447009 6887358..6888020 1 NC_022657.1 hypothetical protein 6888020 17447009 AFR_31710 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737655.1 6887358 D 1246995 CDS YP_008737656.1 556569231 17447010 complement(6888010..6889575) 1 NC_022657.1 COG0405 Gamma-glutamyltransferase; gamma-glutamyltransferase 6889575 17447010 AFR_31715 Actinoplanes friuliensis DSM 7358 gamma-glutamyltransferase YP_008737656.1 6888010 R 1246995 CDS YP_008737657.1 556569232 17447011 6890169..6890399 1 NC_022657.1 hypothetical protein 6890399 17447011 AFR_31720 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737657.1 6890169 D 1246995 CDS YP_008737658.1 556569233 17447012 complement(6890396..6892321) 1 NC_022657.1 COG1132 ABC-type multidrug transport system, ATPase and permease components; Lipid A export ATP-binding/permease protein msbA 6892321 17447012 AFR_31725 Actinoplanes friuliensis DSM 7358 Lipid A export ATP-binding/permease protein msbA YP_008737658.1 6890396 R 1246995 CDS YP_008737659.1 556569234 17447013 complement(6892318..6894078) 1 NC_022657.1 COG1132 ABC-type multidrug transport system, ATPase and permease components; Lipid A export ATP-binding/permease protein msbA 6894078 17447013 AFR_31730 Actinoplanes friuliensis DSM 7358 Lipid A export ATP-binding/permease protein msbA YP_008737659.1 6892318 R 1246995 CDS YP_008737660.1 556569235 17447014 complement(6894166..6895497) 1 NC_022657.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); putative alpha/beta hydrolase fold protein 6895497 17447014 AFR_31735 Actinoplanes friuliensis DSM 7358 putative alpha/beta hydrolase fold protein YP_008737660.1 6894166 R 1246995 CDS YP_008737661.1 556569236 17447015 complement(6895732..6898746) 1 NC_022657.1 COG2866 Predicted carboxypeptidase; peptidase M14, carboxypeptidase A 6898746 17447015 AFR_31740 Actinoplanes friuliensis DSM 7358 peptidase M14, carboxypeptidase A YP_008737661.1 6895732 R 1246995 CDS YP_008737662.1 556569237 17447016 6899053..6900072 1 NC_022657.1 COG2133 Glucose/sorbosone dehydrogenases; putative oxidoreductase 6900072 17447016 AFR_31745 Actinoplanes friuliensis DSM 7358 putative oxidoreductase YP_008737662.1 6899053 D 1246995 CDS YP_008737663.1 556569238 17447017 complement(6900088..6900282) 1 NC_022657.1 hypothetical protein 6900282 17447017 AFR_31750 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737663.1 6900088 R 1246995 CDS YP_008737664.1 556569239 17447018 complement(6900460..6900753) 1 NC_022657.1 hypothetical protein 6900753 17447018 AFR_31755 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737664.1 6900460 R 1246995 CDS YP_008737665.1 556569240 17447019 complement(6900793..6902463) 1 NC_022657.1 COG0591 Na+/proline symporter; putative sodium:solute symporter 6902463 17447019 AFR_31760 Actinoplanes friuliensis DSM 7358 putative sodium:solute symporter YP_008737665.1 6900793 R 1246995 CDS YP_008737666.1 556569241 17447020 6902619..6904493 1 NC_022657.1 COG2936 Predicted acyl esterases; x-prolyl-dipeptidyl aminopeptidase 6904493 17447020 AFR_31765 Actinoplanes friuliensis DSM 7358 x-prolyl-dipeptidyl aminopeptidase YP_008737666.1 6902619 D 1246995 CDS YP_008737667.1 556569242 17447021 6904608..6907253 1 NC_022657.1 COG1012 NAD-dependent aldehyde dehydrogenases; glycosyl hydrolase family 98 putative carbohydrate binding module 6907253 17447021 AFR_31770 Actinoplanes friuliensis DSM 7358 glycosyl hydrolase family 98 putative carbohydrate binding module YP_008737667.1 6904608 D 1246995 CDS YP_008737668.1 556569243 17447022 complement(6907237..6907917) 1 NC_022657.1 COG1309 Transcriptional regulator; Tetracycline repressor protein class H 6907917 17447022 AFR_31775 Actinoplanes friuliensis DSM 7358 Tetracycline repressor protein class H YP_008737668.1 6907237 R 1246995 CDS YP_008737669.1 556569244 17447023 6908003..6909205 1 NC_022657.1 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases; Methylenetetrahydrofolate-tRNA-(uracil-5-)- methyltransferase trmFO 6909205 17447023 AFR_31780 Actinoplanes friuliensis DSM 7358 Methylenetetrahydrofolate-tRNA-(uracil-5-)- methyltransferase trmFO YP_008737669.1 6908003 D 1246995 CDS YP_008737670.1 556569245 17447024 complement(6909153..6909809) 1 NC_022657.1 COG0637 Predicted phosphatase/phosphohexomutase; putative haloacid dehalogenase-like hydrolase 6909809 17447024 AFR_31785 Actinoplanes friuliensis DSM 7358 putative haloacid dehalogenase-like hydrolase YP_008737670.1 6909153 R 1246995 CDS YP_008737671.1 556569246 17447025 complement(6909806..6910672) 1 NC_022657.1 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases; luciferase-like monooxygenase 6910672 17447025 AFR_31790 Actinoplanes friuliensis DSM 7358 luciferase-like monooxygenase YP_008737671.1 6909806 R 1246995 CDS YP_008737672.1 556569247 17447026 6910964..6911953 1 NC_022657.1 COG0463 Glycosyltransferases involved in cell wall biogenesis; family 2 glycosyl transferase 6911953 17447026 AFR_31795 Actinoplanes friuliensis DSM 7358 family 2 glycosyl transferase YP_008737672.1 6910964 D 1246995 CDS YP_008737673.1 556569248 17447027 complement(6911947..6912948) 1 NC_022657.1 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases; putative luciferase-like monooxygenase 6912948 17447027 AFR_31800 Actinoplanes friuliensis DSM 7358 putative luciferase-like monooxygenase YP_008737673.1 6911947 R 1246995 CDS YP_008737674.1 556569249 17447028 complement(6912958..6914850) 1 NC_022657.1 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; RNA polymerase sigma factor rpoD 6914850 17447028 AFR_31805 Actinoplanes friuliensis DSM 7358 RNA polymerase sigma factor rpoD YP_008737674.1 6912958 R 1246995 CDS YP_008737675.1 556569250 17447029 6915052..6915468 1 NC_022657.1 COG2172 Anti-sigma regulatory factor (Ser/Thr protein kinase); Serine-protein kinase rsbW 6915468 17447029 AFR_31810 Actinoplanes friuliensis DSM 7358 Serine-protein kinase rsbW YP_008737675.1 6915052 D 1246995 CDS YP_008737676.1 556569251 17447030 6915588..6916727 1 NC_022657.1 COG2208 Serine phosphatase RsbU, regulator of sigma subunit; Protein icfG 6916727 17447030 AFR_31815 Actinoplanes friuliensis DSM 7358 Protein icfG YP_008737676.1 6915588 D 1246995 CDS YP_008737677.1 556569252 17447031 6916822..6917286 1 NC_022657.1 COG1846 Transcriptional regulators; putative MarR-family transcriptional regulator 6917286 17447031 AFR_31820 Actinoplanes friuliensis DSM 7358 putative MarR-family transcriptional regulator YP_008737677.1 6916822 D 1246995 CDS YP_008737678.1 556569253 17447032 6917301..6918173 1 NC_022657.1 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases; Alkanesulfonate monooxygenase 6918173 17447032 AFR_31825 Actinoplanes friuliensis DSM 7358 Alkanesulfonate monooxygenase YP_008737678.1 6917301 D 1246995 CDS YP_008737679.1 556569254 17447033 complement(6918629..6918979) 1 NC_022657.1 hypothetical protein 6918979 17447033 AFR_31830 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737679.1 6918629 R 1246995 CDS YP_008737680.1 556569255 17447034 6919218..6919655 1 NC_022657.1 hypothetical protein 6919655 17447034 AFR_31835 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737680.1 6919218 D 1246995 CDS YP_008737681.1 556569256 17447035 6919694..6921022 1 NC_022657.1 COG1686 D-alanyl-D-alanine carboxypeptidase; putative D-alanyl-D-alanine carboxypeptidase 6921022 17447035 AFR_31840 Actinoplanes friuliensis DSM 7358 putative D-alanyl-D-alanine carboxypeptidase YP_008737681.1 6919694 D 1246995 CDS YP_008737682.1 556569257 17447036 complement(6921032..6921529) 1 NC_022657.1 hypothetical protein 6921529 17447036 AFR_31845 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737682.1 6921032 R 1246995 CDS YP_008737683.1 556569258 17447037 6921643..6921831 1 NC_022657.1 hypothetical protein 6921831 17447037 AFR_31850 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737683.1 6921643 D 1246995 CDS YP_008737684.1 556569259 17447038 6921828..6922529 1 NC_022657.1 COG2120 Uncharacterized proteins, LmbE homologs; putative GlcNAc-PI de-N-acetylase 6922529 17447038 AFR_31855 Actinoplanes friuliensis DSM 7358 putative GlcNAc-PI de-N-acetylase YP_008737684.1 6921828 D 1246995 CDS YP_008737685.1 556569260 17447039 6922659..6923576 1 NC_022657.1 COG1191 DNA-directed RNA polymerase specialized sigma subunit; RNA polymerase sigma factor rpoD 6923576 17447039 AFR_31860 Actinoplanes friuliensis DSM 7358 RNA polymerase sigma factor rpoD YP_008737685.1 6922659 D 1246995 CDS YP_008737686.1 556569261 17447040 complement(6923629..6925914) 1 NC_022657.1 COG3973 Superfamily I DNA and RNA helicases; putative helicase 6925914 17447040 AFR_31865 Actinoplanes friuliensis DSM 7358 putative helicase YP_008737686.1 6923629 R 1246995 CDS YP_008737687.1 556569262 17447041 6926152..6926670 1 NC_022657.1 hypothetical protein 6926670 17447041 AFR_31870 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737687.1 6926152 D 1246995 CDS YP_008737688.1 556569263 17447042 complement(6926771..6927619) 1 NC_022657.1 COG1191 DNA-directed RNA polymerase specialized sigma subunit; putative RNA polymerase sigma factor 6927619 17447042 AFR_31875 Actinoplanes friuliensis DSM 7358 putative RNA polymerase sigma factor YP_008737688.1 6926771 R 1246995 CDS YP_008737689.1 556569264 17447043 6927869..6929392 1 NC_022657.1 COG0513 Superfamily II DNA and RNA helicases; Pre-mRNA-processing ATP-dependent RNA helicase PRP5 6929392 17447043 AFR_31880 Actinoplanes friuliensis DSM 7358 Pre-mRNA-processing ATP-dependent RNA helicase PRP5 YP_008737689.1 6927869 D 1246995 CDS YP_008737690.1 556569265 17447044 complement(6929461..6929925) 1 NC_022657.1 hypothetical protein 6929925 17447044 AFR_31885 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737690.1 6929461 R 1246995 CDS YP_008737691.1 556569266 17447045 complement(6931340..6931846) 1 NC_022657.1 COG2353 Uncharacterized conserved protein; hypothetical protein 6931846 17447045 AFR_31890 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737691.1 6931340 R 1246995 CDS YP_008737692.1 556569267 17447046 complement(6931900..6934557) 1 NC_022657.1 COG3899 Predicted ATPase; hypothetical protein 6934557 17447046 AFR_31895 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737692.1 6931900 R 1246995 CDS YP_008737693.1 556569268 17447047 complement(6934567..6935211) 1 NC_022657.1 hypothetical protein 6935211 17447047 AFR_31900 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737693.1 6934567 R 1246995 CDS YP_008737694.1 556569269 17447048 6935253..6935408 1 NC_022657.1 hypothetical protein 6935408 17447048 AFR_31905 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737694.1 6935253 D 1246995 CDS YP_008737695.1 556569270 17447049 complement(6935412..6936452) 1 NC_022657.1 COG4850 Uncharacterized conserved protein; Actin patch protein 1 6936452 17447049 AFR_31910 Actinoplanes friuliensis DSM 7358 Actin patch protein 1 YP_008737695.1 6935412 R 1246995 CDS YP_008737696.1 556569271 17447050 complement(6936566..6937243) 1 NC_022657.1 hypothetical protein 6937243 17447050 AFR_31915 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737696.1 6936566 R 1246995 CDS YP_008737697.1 556569272 17447051 complement(6937429..6937776) 1 NC_022657.1 hypothetical protein 6937776 17447051 AFR_31920 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737697.1 6937429 R 1246995 CDS YP_008737698.1 556569273 17447052 6937868..6938716 1 NC_022657.1 COG0846 NAD-dependent protein deacetylases, SIR2 family; silent information regulator protein Sir2 6938716 17447052 AFR_31925 Actinoplanes friuliensis DSM 7358 silent information regulator protein Sir2 YP_008737698.1 6937868 D 1246995 CDS YP_008737699.1 556569274 17447053 6938900..6939922 1 NC_022657.1 COG1609 Transcriptional regulators; LacI family transcriptional regulator 6939922 17447053 AFR_31930 Actinoplanes friuliensis DSM 7358 LacI family transcriptional regulator YP_008737699.1 6938900 D 1246995 CDS YP_008737700.1 556569275 17447054 6940042..6941727 1 NC_022657.1 COG0747 ABC-type dipeptide transport system, periplasmic component; family 5 extracellular solute-binding protein 6941727 17447054 AFR_31935 Actinoplanes friuliensis DSM 7358 family 5 extracellular solute-binding protein YP_008737700.1 6940042 D 1246995 CDS YP_008737701.1 556569276 17447055 6941808..6942941 1 NC_022657.1 COG4608 ABC-type oligopeptide transport system, ATPase component; Methionine import ATP-binding protein metN 6942941 17447055 AFR_31940 Actinoplanes friuliensis DSM 7358 Methionine import ATP-binding protein metN YP_008737701.1 6941808 D 1246995 CDS YP_008737702.1 556569277 17447056 6942938..6943918 1 NC_022657.1 COG0601 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components; ABC transporter permease 6943918 17447056 AFR_31945 Actinoplanes friuliensis DSM 7358 ABC transporter permease YP_008737702.1 6942938 D 1246995 CDS YP_008737703.1 556569278 17447057 6943922..6945007 1 NC_022657.1 COG1173 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components; binding-protein-dependent transport systems inner membrane component 6945007 17447057 AFR_31950 Actinoplanes friuliensis DSM 7358 binding-protein-dependent transport systems inner membrane component YP_008737703.1 6943922 D 1246995 CDS YP_008737704.1 556569279 17447058 6945004..6946011 1 NC_022657.1 COG0444 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component; putative ABC transporter ATP-binding protein 6946011 17447058 AFR_31955 Actinoplanes friuliensis DSM 7358 putative ABC transporter ATP-binding protein YP_008737704.1 6945004 D 1246995 CDS YP_008737705.1 556569280 17447059 6946085..6947488 1 NC_022657.1 COG2723 Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase; beta-galactosidase 6947488 17447059 AFR_31960 Actinoplanes friuliensis DSM 7358 beta-galactosidase YP_008737705.1 6946085 D 1246995 CDS YP_008737706.1 556569281 17447060 complement(6947552..6948790) 1 NC_022657.1 COG1940 Transcriptional regulator/sugar kinase; rok family protein 6948790 17447060 AFR_31965 Actinoplanes friuliensis DSM 7358 rok family protein YP_008737706.1 6947552 R 1246995 CDS YP_008737707.1 556569282 17447061 6948937..6949770 1 NC_022657.1 COG0500 SAM-dependent methyltransferases; 3-demethylubiquinone-9 3-methyltransferase 6949770 17447061 AFR_31970 Actinoplanes friuliensis DSM 7358 3-demethylubiquinone-9 3-methyltransferase YP_008737707.1 6948937 D 1246995 CDS YP_008737708.1 556569283 17447062 6949827..6950036 1 NC_022657.1 hypothetical protein 6950036 17447062 AFR_31975 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737708.1 6949827 D 1246995 CDS YP_008737709.1 556569284 17447063 6950180..6951691 1 NC_022657.1 COG2199 FOG: GGDEF domain; hypothetical protein 6951691 17447063 AFR_31980 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737709.1 6950180 D 1246995 CDS YP_008737710.1 556569285 17447064 6951734..6952129 1 NC_022657.1 COG1846 Transcriptional regulators; transcriptional regulator 6952129 17447064 AFR_31985 Actinoplanes friuliensis DSM 7358 transcriptional regulator YP_008737710.1 6951734 D 1246995 CDS YP_008737711.1 556569286 17447065 6952188..6953063 1 NC_022657.1 COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases); oxidoreductase 6953063 17447065 AFR_31990 Actinoplanes friuliensis DSM 7358 oxidoreductase YP_008737711.1 6952188 D 1246995 CDS YP_008737712.1 556569287 17447066 complement(6953373..6953747) 1 NC_022657.1 COG0662 Mannose-6-phosphate isomerase; hypothetical protein 6953747 17447066 AFR_31995 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737712.1 6953373 R 1246995 CDS YP_008737713.1 556569288 17447067 6953821..6954264 1 NC_022657.1 COG1846 Transcriptional regulators; Multiple antibiotic resistance protein marR 6954264 17447067 AFR_32000 Actinoplanes friuliensis DSM 7358 Multiple antibiotic resistance protein marR YP_008737713.1 6953821 D 1246995 CDS YP_008737714.1 556569289 17447068 6954320..6954904 1 NC_022657.1 hypothetical protein 6954904 17447068 AFR_32005 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737714.1 6954320 D 1246995 CDS YP_008737715.1 556569290 17447069 complement(6955443..6955895) 1 NC_022657.1 hypothetical protein 6955895 17447069 AFR_32010 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737715.1 6955443 R 1246995 CDS YP_008737716.1 556569291 17447070 6956394..6957275 1 NC_022657.1 COG1396 Predicted transcriptional regulators; DNA-binding protein 6957275 17447070 AFR_32015 Actinoplanes friuliensis DSM 7358 DNA-binding protein YP_008737716.1 6956394 D 1246995 CDS YP_008737717.1 556569292 17447071 complement(6957291..6957506) 1 NC_022657.1 hypothetical protein 6957506 17447071 AFR_32020 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737717.1 6957291 R 1246995 CDS YP_008737718.1 556569293 17447072 complement(6957786..6960308) 1 NC_022657.1 COG0188 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit; DNA topoisomerase IV subunit A 6960308 17447072 AFR_32025 Actinoplanes friuliensis DSM 7358 DNA topoisomerase IV subunit A YP_008737718.1 6957786 R 1246995 CDS YP_008737719.1 556569294 17447073 complement(6960325..6962295) 1 NC_022657.1 COG0187 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit; DNA gyrase subunit B 6962295 17447073 AFR_32030 Actinoplanes friuliensis DSM 7358 DNA gyrase subunit B YP_008737719.1 6960325 R 1246995 CDS YP_008737720.1 556569295 17447074 complement(6967773..6968408) 1 NC_022657.1 COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain); adenylate/guanylate cyclase 6968408 17447074 AFR_32045 Actinoplanes friuliensis DSM 7358 adenylate/guanylate cyclase YP_008737720.1 6967773 R 1246995 CDS YP_008737721.1 556569296 17447075 6968578..6971430 1 NC_022657.1 COG3899 Predicted ATPase; HTH-type transcriptional regulator malT 6971430 17447075 AFR_32050 Actinoplanes friuliensis DSM 7358 HTH-type transcriptional regulator malT YP_008737721.1 6968578 D 1246995 CDS YP_008737722.1 556569297 17447076 6971595..6972368 1 NC_022657.1 hypothetical protein 6972368 17447076 AFR_32055 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737722.1 6971595 D 1246995 CDS YP_008737723.1 556569298 17447077 complement(6972434..6972955) 1 NC_022657.1 hypothetical protein 6972955 17447077 AFR_32060 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737723.1 6972434 R 1246995 CDS YP_008737724.1 556569299 17447078 complement(6972997..6974346) 1 NC_022657.1 COG0642 Signal transduction histidine kinase; histidine kinase 6974346 17447078 AFR_32065 Actinoplanes friuliensis DSM 7358 histidine kinase YP_008737724.1 6972997 R 1246995 CDS YP_008737725.1 556569300 17447079 complement(6974339..6975019) 1 NC_022657.1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; putative two-component system response regulator 6975019 17447079 AFR_32070 Actinoplanes friuliensis DSM 7358 putative two-component system response regulator YP_008737725.1 6974339 R 1246995 CDS YP_008737726.1 556569301 17447080 complement(6975049..6976290) 1 NC_022657.1 COG4941 Predicted RNA polymerase sigma factor containing a TPR repeat domain; putative ECF subfamily RNA polymerase sigma-24 subunit 6976290 17447080 AFR_32075 Actinoplanes friuliensis DSM 7358 putative ECF subfamily RNA polymerase sigma-24 subunit YP_008737726.1 6975049 R 1246995 CDS YP_008737727.1 556569302 17447081 complement(6976287..6976646) 1 NC_022657.1 COG3795 Uncharacterized protein conserved in bacteria; DGPF domain-containing protein 6976646 17447081 AFR_32080 Actinoplanes friuliensis DSM 7358 DGPF domain-containing protein YP_008737727.1 6976287 R 1246995 CDS YP_008737728.1 556569303 17447082 6977092..6980490 1 NC_022657.1 COG3291 FOG: PKD repeat; coagulation factor 5/8 type domain-containing protein 6980490 17447082 AFR_32085 Actinoplanes friuliensis DSM 7358 coagulation factor 5/8 type domain-containing protein YP_008737728.1 6977092 D 1246995 CDS YP_008737729.1 556569304 17447083 6980594..6981922 1 NC_022657.1 COG1520 FOG: WD40-like repeat; hypothetical protein 6981922 17447083 AFR_32090 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737729.1 6980594 D 1246995 CDS YP_008737730.1 556569305 17447084 6981932..6983266 1 NC_022657.1 COG1520 FOG: WD40-like repeat; hypothetical protein 6983266 17447084 AFR_32095 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737730.1 6981932 D 1246995 CDS YP_008737731.1 556569306 17447085 6983461..6984252 1 NC_022657.1 COG3568 Metal-dependent hydrolase; endonuclease/exonuclease/phosphatase 6984252 17447085 AFR_32100 Actinoplanes friuliensis DSM 7358 endonuclease/exonuclease/phosphatase YP_008737731.1 6983461 D 1246995 CDS YP_008737732.1 556569307 17447086 complement(6984315..6986957) 1 NC_022657.1 COG3291 FOG: PKD repeat; hypothetical protein 6986957 17447086 AFR_32105 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737732.1 6984315 R 1246995 CDS YP_008737733.1 556569308 17447087 6987175..6987735 1 NC_022657.1 COG3544 Uncharacterized protein conserved in bacteria; hypothetical protein 6987735 17447087 AFR_32110 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737733.1 6987175 D 1246995 CDS YP_008737734.1 556569309 17447088 complement(6987803..6989209) 1 NC_022657.1 COG3291 FOG: PKD repeat; hypothetical protein 6989209 17447088 AFR_32115 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737734.1 6987803 R 1246995 CDS YP_008737735.1 556569310 17447089 6989451..6990509 1 NC_022657.1 COG1609 Transcriptional regulators; LacI family transcriptional regulator 6990509 17447089 AFR_32120 Actinoplanes friuliensis DSM 7358 LacI family transcriptional regulator YP_008737735.1 6989451 D 1246995 CDS YP_008737736.1 556569311 17447090 6990720..6991037 1 NC_022657.1 COG4669 Type III secretory pathway, lipoprotein EscJ; hypothetical protein 6991037 17447090 AFR_32125 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737736.1 6990720 D 1246995 CDS YP_008737737.1 556569312 17447091 complement(6992015..6993115) 1 NC_022657.1 COG0387 Ca2+/H+ antiporter; putative sodium-calcium/proton antiporter 6993115 17447091 AFR_32130 Actinoplanes friuliensis DSM 7358 putative sodium-calcium/proton antiporter YP_008737737.1 6992015 R 1246995 CDS YP_008737738.1 556569313 17447092 6993262..6994671 1 NC_022657.1 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases; pentachlorophenol 4-monooxygenase 6994671 17447092 AFR_32135 Actinoplanes friuliensis DSM 7358 pentachlorophenol 4-monooxygenase YP_008737738.1 6993262 D 1246995 CDS YP_008737739.1 556569314 17447093 6994676..6995848 1 NC_022657.1 COG2755 Lysophospholipase L1 and related esterases; putative GDSL-like lipase/acylhydrolase 6995848 17447093 AFR_32140 Actinoplanes friuliensis DSM 7358 putative GDSL-like lipase/acylhydrolase YP_008737739.1 6994676 D 1246995 CDS YP_008737740.1 556569315 17447094 6995916..6997169 1 NC_022657.1 COG5659 FOG: Transposase; putative transposase 6997169 17447094 AFR_32145 Actinoplanes friuliensis DSM 7358 putative transposase YP_008737740.1 6995916 D 1246995 CDS YP_008737741.1 556569316 17447095 complement(6997352..7000567) 1 NC_022657.1 COG3629 DNA-binding transcriptional activator of the SARP family; LuxR family transcriptional regulator 7000567 17447095 AFR_32150 Actinoplanes friuliensis DSM 7358 LuxR family transcriptional regulator YP_008737741.1 6997352 R 1246995 CDS YP_008737742.1 556569317 17447096 complement(7000528..7001511) 1 NC_022657.1 COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases; phosphoglycerate dehydrogenase-like oxidoreductase 7001511 17447096 AFR_32155 Actinoplanes friuliensis DSM 7358 phosphoglycerate dehydrogenase-like oxidoreductase YP_008737742.1 7000528 R 1246995 CDS YP_008737743.1 556569318 17447097 complement(7001492..7002070) 1 NC_022657.1 COG1309 Transcriptional regulator; TetR family transcriptional regulator 7002070 17447097 AFR_32160 Actinoplanes friuliensis DSM 7358 TetR family transcriptional regulator YP_008737743.1 7001492 R 1246995 CDS YP_008737744.1 556569319 17447098 7002124..7002546 1 NC_022657.1 COG3631 Ketosteroid isomerase-related protein; Phenazine biosynthesis protein phzB 2 7002546 17447098 AFR_32165 Actinoplanes friuliensis DSM 7358 Phenazine biosynthesis protein phzB 2 YP_008737744.1 7002124 D 1246995 CDS YP_008737745.1 556569320 17447099 7002642..7003646 1 NC_022657.1 COG0435 Predicted glutathione S-transferase; hypothetical protein 7003646 17447099 AFR_32170 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737745.1 7002642 D 1246995 CDS YP_008737746.1 556569321 17447100 7003667..7004497 1 NC_022657.1 COG1117 ABC-type phosphate transport system, ATPase component; hypothetical protein 7004497 17447100 AFR_32175 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737746.1 7003667 D 1246995 CDS YP_008737747.1 556569322 17447101 complement(7004494..7004985) 1 NC_022657.1 COG1846 Transcriptional regulators; HTH-type transcriptional regulator pecS 7004985 17447101 AFR_32180 Actinoplanes friuliensis DSM 7358 HTH-type transcriptional regulator pecS YP_008737747.1 7004494 R 1246995 CDS YP_008737748.1 556569323 17447102 7005092..7006234 1 NC_022657.1 COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily; Protein pecM 7006234 17447102 AFR_32185 Actinoplanes friuliensis DSM 7358 Protein pecM YP_008737748.1 7005092 D 1246995 CDS YP_008737749.1 556569324 17447103 complement(7005923..7006567) 1 NC_022657.1 COG0702 Predicted nucleoside-diphosphate-sugar epimerases; hypothetical protein 7006567 17447103 AFR_32190 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737749.1 7005923 R 1246995 CDS YP_008737750.1 556569325 17447104 complement(7006564..7007133) 1 NC_022657.1 COG1309 Transcriptional regulator; TetR family transcriptional regulator 7007133 17447104 AFR_32195 Actinoplanes friuliensis DSM 7358 TetR family transcriptional regulator YP_008737750.1 7006564 R 1246995 CDS YP_008737751.1 556569326 17447105 7007230..7008150 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); dehydrogenase 7008150 17447105 AFR_32200 Actinoplanes friuliensis DSM 7358 dehydrogenase YP_008737751.1 7007230 D 1246995 CDS YP_008737752.1 556569327 17447106 7008181..7011045 1 NC_022657.1 zinc finger SWIM domain-containing protein 7011045 17447106 AFR_32205 Actinoplanes friuliensis DSM 7358 zinc finger SWIM domain-containing protein YP_008737752.1 7008181 D 1246995 CDS YP_008737753.1 556569328 17447107 7011136..7012197 1 NC_022657.1 COG0714 MoxR-like ATPases; putative ATPase 7012197 17447107 AFR_32210 Actinoplanes friuliensis DSM 7358 putative ATPase YP_008737753.1 7011136 D 1246995 CDS YP_008737754.1 556569329 17447108 complement(7012232..7012456) 1 NC_022657.1 hypothetical protein 7012456 17447108 AFR_32215 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737754.1 7012232 R 1246995 CDS YP_008737755.1 556569330 17447109 7013135..7015057 1 NC_022657.1 hypothetical protein 7015057 17447109 AFR_32220 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737755.1 7013135 D 1246995 CDS YP_008737756.1 556569331 17447110 7015083..7016267 1 NC_022657.1 hypothetical protein 7016267 17447110 AFR_32225 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737756.1 7015083 D 1246995 CDS YP_008737757.1 556569332 17447111 complement(7016285..7017004) 1 NC_022657.1 COG0388 Predicted amidohydrolase; hypothetical protein 7017004 17447111 AFR_32230 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737757.1 7016285 R 1246995 CDS YP_008737758.1 556569333 17447112 complement(7017058..7017375) 1 NC_022657.1 hypothetical protein 7017375 17447112 AFR_32235 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737758.1 7017058 R 1246995 CDS YP_008737759.1 556569334 17447113 complement(7017378..7017983) 1 NC_022657.1 COG2977 Phosphopantetheinyl transferase component of siderophore synthetase; phosphopantetheinyl transferase 7017983 17447113 AFR_32240 Actinoplanes friuliensis DSM 7358 phosphopantetheinyl transferase YP_008737759.1 7017378 R 1246995 CDS YP_008737760.1 556569335 17447114 complement(7018009..7018815) 1 NC_022657.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); hydrolase 7018815 17447114 AFR_32245 Actinoplanes friuliensis DSM 7358 hydrolase YP_008737760.1 7018009 R 1246995 CDS YP_008737761.1 556569336 17447115 7018880..7019770 1 NC_022657.1 COG0322 Nuclease subunit of the excinuclease complex; excinuclease ABC subunit C 7019770 17447115 AFR_32250 Actinoplanes friuliensis DSM 7358 excinuclease ABC subunit C YP_008737761.1 7018880 D 1246995 CDS YP_008737762.1 556569337 17447116 7019767..7020195 1 NC_022657.1 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; acetyltransferase 7020195 17447116 AFR_32255 Actinoplanes friuliensis DSM 7358 acetyltransferase YP_008737762.1 7019767 D 1246995 CDS YP_008737763.1 556569338 17447117 7020179..7020619 1 NC_022657.1 hypothetical protein 7020619 17447117 AFR_32260 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737763.1 7020179 D 1246995 CDS YP_008737764.1 556569339 17447118 7020631..7021068 1 NC_022657.1 hypothetical protein 7021068 17447118 AFR_32265 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737764.1 7020631 D 1246995 CDS YP_008737765.1 556569340 17447119 7021065..7021538 1 NC_022657.1 COG2110 Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1; hypothetical protein 7021538 17447119 AFR_32270 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737765.1 7021065 D 1246995 CDS YP_008737766.1 556569341 17447120 complement(7021535..7022341) 1 NC_022657.1 COG1120 ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components; ABC-type cobalamin/Fe3+-siderophore transport system ATPase component 7022341 17447120 AFR_32275 Actinoplanes friuliensis DSM 7358 ABC-type cobalamin/Fe3+-siderophore transport system ATPase component YP_008737766.1 7021535 R 1246995 CDS YP_008737767.1 556569342 17447121 complement(7022341..7023372) 1 NC_022657.1 COG4779 ABC-type enterobactin transport system, permease component; ABC transporter permease 7023372 17447121 AFR_32280 Actinoplanes friuliensis DSM 7358 ABC transporter permease YP_008737767.1 7022341 R 1246995 CDS YP_008737768.1 556569343 17447122 complement(7023369..7024433) 1 NC_022657.1 COG0609 ABC-type Fe3+-siderophore transport system, permease component; ABC transporter permease 7024433 17447122 AFR_32285 Actinoplanes friuliensis DSM 7358 ABC transporter permease YP_008737768.1 7023369 R 1246995 CDS YP_008737769.1 556569344 17447123 complement(7024430..7025440) 1 NC_022657.1 COG0614 ABC-type Fe3+-hydroxamate transport system, periplasmic component; periplasmic binding protein 7025440 17447123 AFR_32290 Actinoplanes friuliensis DSM 7358 periplasmic binding protein YP_008737769.1 7024430 R 1246995 CDS YP_008737770.1 556569345 17447124 7025617..7026762 1 NC_022657.1 COG0464 ATPases of the AAA+ class; Cell division control-like protein 7026762 17447124 AFR_32295 Actinoplanes friuliensis DSM 7358 Cell division control-like protein YP_008737770.1 7025617 D 1246995 CDS YP_008737771.1 556569346 17447125 complement(7026759..7027286) 1 NC_022657.1 COG1309 Transcriptional regulator; transcriptional regulator 7027286 17447125 AFR_32300 Actinoplanes friuliensis DSM 7358 transcriptional regulator YP_008737771.1 7026759 R 1246995 CDS YP_008737772.1 556569347 17447126 complement(7027319..7027699) 1 NC_022657.1 pyridoxamine 5'-phosphate oxidase-like protein 7027699 17447126 AFR_32305 Actinoplanes friuliensis DSM 7358 pyridoxamine 5'-phosphate oxidase-like protein YP_008737772.1 7027319 R 1246995 CDS YP_008737773.1 556569348 17447127 complement(7027737..7028315) 1 NC_022657.1 COG1309 Transcriptional regulator; TetR family transcriptional regulator 7028315 17447127 AFR_32310 Actinoplanes friuliensis DSM 7358 TetR family transcriptional regulator YP_008737773.1 7027737 R 1246995 CDS YP_008737774.1 556569349 17447128 7028391..7029014 1 NC_022657.1 COG0702 Predicted nucleoside-diphosphate-sugar epimerases; putative secreted protein 7029014 17447128 AFR_32315 Actinoplanes friuliensis DSM 7358 putative secreted protein YP_008737774.1 7028391 D 1246995 CDS YP_008737775.1 556569350 17447129 complement(7029008..7029478) 1 NC_022657.1 COG1846 Transcriptional regulators; HTH-type transcriptional regulator pecS 7029478 17447129 AFR_32320 Actinoplanes friuliensis DSM 7358 HTH-type transcriptional regulator pecS YP_008737775.1 7029008 R 1246995 CDS YP_008737776.1 556569351 17447130 7029584..7030807 1 NC_022657.1 COG0477 Permeases of the major facilitator superfamily; putative MFS transporter 7030807 17447130 AFR_32325 Actinoplanes friuliensis DSM 7358 putative MFS transporter YP_008737776.1 7029584 D 1246995 CDS YP_008737777.1 556569352 17447131 complement(7030757..7031956) 1 NC_022657.1 COG0104 Adenylosuccinate synthase; putative adenylosuccinate synthetase 7031956 17447131 AFR_32330 Actinoplanes friuliensis DSM 7358 putative adenylosuccinate synthetase YP_008737777.1 7030757 R 1246995 CDS YP_008737778.1 556569353 17447132 complement(7031953..7032921) 1 NC_022657.1 hypothetical protein 7032921 17447132 AFR_32335 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737778.1 7031953 R 1246995 CDS YP_008737779.1 556569354 17447133 complement(7032940..7033935) 1 NC_022657.1 COG0515 Serine/threonine protein kinase; hypothetical protein 7033935 17447133 AFR_32340 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737779.1 7032940 R 1246995 CDS YP_008737780.1 556569355 17447134 complement(7033932..7034684) 1 NC_022657.1 COG1051 ADP-ribose pyrophosphatase; 7,8-dihydro-8-oxoguanine-triphosphatase 7034684 17447134 AFR_32345 Actinoplanes friuliensis DSM 7358 7,8-dihydro-8-oxoguanine-triphosphatase YP_008737780.1 7033932 R 1246995 CDS YP_008737781.1 556569356 17447135 complement(7034966..7035256) 1 NC_022657.1 hypothetical protein 7035256 17447135 AFR_32350 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737781.1 7034966 R 1246995 CDS YP_008737782.1 556569357 17447136 7035467..7036591 1 NC_022657.1 COG4124 Beta-mannanase; hypothetical protein 7036591 17447136 AFR_32355 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737782.1 7035467 D 1246995 CDS YP_008737783.1 556569358 17447137 7037556..7038065 1 NC_022657.1 Hepatocyte growth factor receptor 7038065 17447137 AFR_32360 Actinoplanes friuliensis DSM 7358 Hepatocyte growth factor receptor YP_008737783.1 7037556 D 1246995 CDS YP_008737784.1 556569359 17447138 7039083..7039916 1 NC_022657.1 COG1752 Predicted esterase of the alpha-beta hydrolase superfamily; putative patatin-like phospholipase 7039916 17447138 AFR_32365 Actinoplanes friuliensis DSM 7358 putative patatin-like phospholipase YP_008737784.1 7039083 D 1246995 CDS YP_008737785.1 556569360 17447139 complement(7039913..7040533) 1 NC_022657.1 hypothetical protein 7040533 17447139 AFR_32370 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737785.1 7039913 R 1246995 CDS YP_008737786.1 556569361 17447140 7040633..7041160 1 NC_022657.1 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; putative RNA polymerase ECF-subfamily sigma factor 7041160 17447140 AFR_32375 Actinoplanes friuliensis DSM 7358 putative RNA polymerase ECF-subfamily sigma factor YP_008737786.1 7040633 D 1246995 CDS YP_008737787.1 556569362 17447141 7041157..7041894 1 NC_022657.1 hypothetical protein 7041894 17447141 AFR_32380 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737787.1 7041157 D 1246995 CDS YP_008737788.1 556569363 17447142 7041933..7042532 1 NC_022657.1 COG2041 Sulfite oxidase and related enzymes; hypothetical protein 7042532 17447142 AFR_32385 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737788.1 7041933 D 1246995 CDS YP_008737789.1 556569364 17447143 7042550..7043254 1 NC_022657.1 COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1; putative oxidoreductase 7043254 17447143 AFR_32390 Actinoplanes friuliensis DSM 7358 putative oxidoreductase YP_008737789.1 7042550 D 1246995 CDS YP_008737790.1 556569365 17447144 7043251..7043517 1 NC_022657.1 COG3573 Predicted oxidoreductase; hypothetical protein 7043517 17447144 AFR_32395 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737790.1 7043251 D 1246995 CDS YP_008737791.1 556569366 17447145 complement(7043523..7043909) 1 NC_022657.1 hypothetical protein 7043909 17447145 AFR_32400 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737791.1 7043523 R 1246995 CDS YP_008737792.1 556569367 17447146 7044150..7044953 1 NC_022657.1 COG2755 Lysophospholipase L1 and related esterases; putative GDSL-like lipase/acylhydrolase 7044953 17447146 AFR_32405 Actinoplanes friuliensis DSM 7358 putative GDSL-like lipase/acylhydrolase YP_008737792.1 7044150 D 1246995 CDS YP_008737793.1 556569368 17447147 complement(7045016..7045930) 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); short chain dehydrogenase 7045930 17447147 AFR_32410 Actinoplanes friuliensis DSM 7358 short chain dehydrogenase YP_008737793.1 7045016 R 1246995 CDS YP_008737794.1 556569369 17447148 7046031..7046693 1 NC_022657.1 COG1309 Transcriptional regulator; TetR family transcriptional regulator 7046693 17447148 AFR_32415 Actinoplanes friuliensis DSM 7358 TetR family transcriptional regulator YP_008737794.1 7046031 D 1246995 CDS YP_008737795.1 556569370 17447149 complement(7046694..7047329) 1 NC_022657.1 hypothetical protein 7047329 17447149 AFR_32420 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737795.1 7046694 R 1246995 CDS YP_008737796.1 556569371 17447150 7047600..7048010 1 NC_022657.1 hypothetical protein 7048010 17447150 AFR_32425 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737796.1 7047600 D 1246995 CDS YP_008737797.1 556569372 17447151 complement(7048048..7049235) 1 NC_022657.1 COG0050 GTPases - translation elongation factors; translation elongation factor Tu 7049235 17447151 AFR_32430 Actinoplanes friuliensis DSM 7358 translation elongation factor Tu YP_008737797.1 7048048 R 1246995 CDS YP_008737798.1 556569373 17447152 complement(7049478..7050260) 1 NC_022657.1 COG3786 Uncharacterized protein conserved in bacteria; hypothetical protein 7050260 17447152 AFR_32435 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737798.1 7049478 R 1246995 CDS YP_008737799.1 556569374 17447153 complement(7050280..7052052) 1 NC_022657.1 COG0515 Serine/threonine protein kinase; serine/threonine protein kinase 7052052 17447153 AFR_32440 Actinoplanes friuliensis DSM 7358 serine/threonine protein kinase YP_008737799.1 7050280 R 1246995 CDS YP_008737800.1 556569375 17447154 7052192..7053127 1 NC_022657.1 COG3173 Predicted aminoglycoside phosphotransferase; aminoglycoside phosphotransferase 7053127 17447154 AFR_32445 Actinoplanes friuliensis DSM 7358 aminoglycoside phosphotransferase YP_008737800.1 7052192 D 1246995 CDS YP_008737801.1 556569376 17447155 7053210..7055282 1 NC_022657.1 COG0642 Signal transduction histidine kinase; multi-sensor hybrid histidine kinase 7055282 17447155 AFR_32450 Actinoplanes friuliensis DSM 7358 multi-sensor hybrid histidine kinase YP_008737801.1 7053210 D 1246995 CDS YP_008737802.1 556569377 17447156 complement(7055400..7055711) 1 NC_022657.1 hypothetical protein 7055711 17447156 AFR_32455 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737802.1 7055400 R 1246995 CDS YP_008737803.1 556569378 17447157 complement(7055745..7056185) 1 NC_022657.1 hypothetical protein 7056185 17447157 AFR_32460 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737803.1 7055745 R 1246995 CDS YP_008737804.1 556569379 17447158 complement(7056211..7057170) 1 NC_022657.1 hypothetical protein 7057170 17447158 AFR_32465 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737804.1 7056211 R 1246995 CDS YP_008737805.1 556569380 17447159 complement(7057172..7057585) 1 NC_022657.1 hypothetical protein 7057585 17447159 AFR_32470 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737805.1 7057172 R 1246995 CDS YP_008737806.1 556569381 17447160 complement(7057603..7057977) 1 NC_022657.1 hypothetical protein 7057977 17447160 AFR_32475 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737806.1 7057603 R 1246995 CDS YP_008737807.1 556569382 17447161 complement(7058166..7059113) 1 NC_022657.1 COG4225 Predicted unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins; glycosyl hydrolase family 88 7059113 17447161 AFR_32480 Actinoplanes friuliensis DSM 7358 glycosyl hydrolase family 88 YP_008737807.1 7058166 R 1246995 CDS YP_008737808.1 556569383 17447162 complement(7059110..7060048) 1 NC_022657.1 COG0462 Phosphoribosylpyrophosphate synthetase; ribose-phosphate pyrophosphokinase 7060048 17447162 AFR_32485 Actinoplanes friuliensis DSM 7358 ribose-phosphate pyrophosphokinase YP_008737808.1 7059110 R 1246995 CDS YP_008737809.1 556569384 17447163 7060164..7060991 1 NC_022657.1 COG1136 ABC-type antimicrobial peptide transport system, ATPase component; Methionine import ATP-binding protein metN 1 7060991 17447163 AFR_32490 Actinoplanes friuliensis DSM 7358 Methionine import ATP-binding protein metN 1 YP_008737809.1 7060164 D 1246995 CDS YP_008737810.1 556569385 17447164 complement(7060969..7061439) 1 NC_022657.1 COG1764 Predicted redox protein, regulator of disulfide bond formation; OsmC family protein 7061439 17447164 AFR_32495 Actinoplanes friuliensis DSM 7358 OsmC family protein YP_008737810.1 7060969 R 1246995 CDS YP_008737811.1 556569386 17447165 complement(7061460..7062110) 1 NC_022657.1 COG1136 ABC-type antimicrobial peptide transport system, ATPase component; spermidine/putrescine import ATP-binding protein potA 7062110 17447165 AFR_32500 Actinoplanes friuliensis DSM 7358 spermidine/putrescine import ATP-binding protein potA YP_008737811.1 7061460 R 1246995 CDS YP_008737812.1 556569387 17447166 complement(7062107..7065142) 1 NC_022657.1 putative permease 7065142 17447166 AFR_32505 Actinoplanes friuliensis DSM 7358 putative permease YP_008737812.1 7062107 R 1246995 CDS YP_008737813.1 556569388 17447167 complement(7065139..7068144) 1 NC_022657.1 putative permease 7068144 17447167 AFR_32510 Actinoplanes friuliensis DSM 7358 putative permease YP_008737813.1 7065139 R 1246995 CDS YP_008737814.1 556569389 17447168 complement(7068188..7069162) 1 NC_022657.1 COG0598 Mg2+ and Co2+ transporters; putative CorA-like magnesium transporter 7069162 17447168 AFR_32515 Actinoplanes friuliensis DSM 7358 putative CorA-like magnesium transporter YP_008737814.1 7068188 R 1246995 CDS YP_008737815.1 556569390 17447169 complement(7069231..7070427) 1 NC_022657.1 alginate lyase 2 7070427 17447169 AFR_32520 Actinoplanes friuliensis DSM 7358 alginate lyase 2 YP_008737815.1 7069231 R 1246995 CDS YP_008737816.1 556569391 17447170 7070649..7071671 1 NC_022657.1 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases; monooxygenase 7071671 17447170 AFR_32525 Actinoplanes friuliensis DSM 7358 monooxygenase YP_008737816.1 7070649 D 1246995 CDS YP_008737817.1 556569392 17447171 7071694..7072449 1 NC_022657.1 hypothetical protein 7072449 17447171 AFR_32530 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737817.1 7071694 D 1246995 CDS YP_008737818.1 556569393 17447172 7072546..7074834 1 NC_022657.1 hypothetical protein 7074834 17447172 AFR_32535 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737818.1 7072546 D 1246995 CDS YP_008737819.1 556569394 17447173 7074837..7075424 1 NC_022657.1 hypothetical protein 7075424 17447173 AFR_32540 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737819.1 7074837 D 1246995 CDS YP_008737820.1 556569395 17447174 complement(7075378..7076475) 1 NC_022657.1 COG2304 Uncharacterized protein containing a von Willebrand factor type A (vWA) domain; hypothetical protein 7076475 17447174 AFR_32545 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737820.1 7075378 R 1246995 CDS YP_008737821.1 556569396 17447175 complement(7076475..7077452) 1 NC_022657.1 COG2304 Uncharacterized protein containing a von Willebrand factor type A (vWA) domain; hypothetical protein 7077452 17447175 AFR_32550 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737821.1 7076475 R 1246995 CDS YP_008737822.1 556569397 17447176 complement(7077449..7078315) 1 NC_022657.1 COG1721 Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain); hypothetical protein 7078315 17447176 AFR_32555 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737822.1 7077449 R 1246995 CDS YP_008737823.1 556569398 17447177 complement(7078352..7079347) 1 NC_022657.1 COG0714 MoxR-like ATPases; putative ATPase associated with various cellular activities 7079347 17447177 AFR_32560 Actinoplanes friuliensis DSM 7358 putative ATPase associated with various cellular activities YP_008737823.1 7078352 R 1246995 CDS YP_008737824.1 556569399 17447178 complement(7079379..7080194) 1 NC_022657.1 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain; Trypsin-like serine protease 7080194 17447178 AFR_32565 Actinoplanes friuliensis DSM 7358 Trypsin-like serine protease YP_008737824.1 7079379 R 1246995 CDS YP_008737825.1 556569400 17447179 complement(7080276..7083611) 1 NC_022657.1 COG1020 Non-ribosomal peptide synthetase modules and related proteins; non-ribosomal peptide synthase:amino acid adenylation 7083611 17447179 AFR_32570 Actinoplanes friuliensis DSM 7358 non-ribosomal peptide synthase:amino acid adenylation YP_008737825.1 7080276 R 1246995 CDS YP_008737826.1 556569401 17447180 complement(7083635..7084699) 1 NC_022657.1 COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases; succinyl-diaminopimelate desuccinylase 7084699 17447180 AFR_32575 Actinoplanes friuliensis DSM 7358 succinyl-diaminopimelate desuccinylase YP_008737826.1 7083635 R 1246995 CDS YP_008737827.1 556569402 17447181 7084768..7085055 1 NC_022657.1 hypothetical protein 7085055 17447181 AFR_32580 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737827.1 7084768 D 1246995 CDS YP_008737828.1 556569403 17447182 7085170..7086429 1 NC_022657.1 COG0477 Permeases of the major facilitator superfamily; major Facilitator Superfamily protein 7086429 17447182 AFR_32585 Actinoplanes friuliensis DSM 7358 major Facilitator Superfamily protein YP_008737828.1 7085170 D 1246995 CDS YP_008737829.1 556569404 17447183 complement(7086864..7088222) 1 NC_022657.1 COG2273 Beta-glucanase/Beta-glucan synthetase; glycoside hydrolase family protein 7088222 17447183 AFR_32590 Actinoplanes friuliensis DSM 7358 glycoside hydrolase family protein YP_008737829.1 7086864 R 1246995 CDS YP_008737830.1 556569405 17447184 7089107..7092565 1 NC_022657.1 hypothetical protein 7092565 17447184 AFR_32595 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737830.1 7089107 D 1246995 CDS YP_008737831.1 556569406 17447185 7092800..7099513 1 NC_022657.1 COG3209 Rhs family protein; Rhs family protein-like protein 7099513 17447185 AFR_32600 Actinoplanes friuliensis DSM 7358 Rhs family protein-like protein YP_008737831.1 7092800 D 1246995 CDS YP_008737832.1 556569407 17447186 complement(7100500..7101918) 1 NC_022657.1 VWA containing CoxE family protein 7101918 17447186 AFR_32605 Actinoplanes friuliensis DSM 7358 VWA containing CoxE family protein YP_008737832.1 7100500 R 1246995 CDS YP_008737833.1 556569408 17447188 complement(7103216..7103650) 1 NC_022657.1 hypothetical protein 7103650 17447188 AFR_32610 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737833.1 7103216 R 1246995 CDS YP_008737834.1 556569409 17447189 7103958..7104389 1 NC_022657.1 putative SsgA-family protein 7104389 17447189 AFR_32615 Actinoplanes friuliensis DSM 7358 putative SsgA-family protein YP_008737834.1 7103958 D 1246995 CDS YP_008737835.1 556569410 17447190 7104667..7105593 1 NC_022657.1 COG2207 AraC-type DNA-binding domain-containing proteins; AraC family transcriptional regulator 7105593 17447190 AFR_32620 Actinoplanes friuliensis DSM 7358 AraC family transcriptional regulator YP_008737835.1 7104667 D 1246995 CDS YP_008737836.1 556569411 17447191 7105700..7106155 1 NC_022657.1 COG1959 Predicted transcriptional regulator; AsnC family transcriptional regulator 7106155 17447191 AFR_32625 Actinoplanes friuliensis DSM 7358 AsnC family transcriptional regulator YP_008737836.1 7105700 D 1246995 CDS YP_008737837.1 556569412 17447192 7106223..7106396 1 NC_022657.1 hypothetical protein 7106396 17447192 AFR_32630 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737837.1 7106223 D 1246995 CDS YP_008737838.1 556569413 17447193 complement(7106403..7107323) 1 NC_022657.1 hypothetical protein 7107323 17447193 AFR_32635 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737838.1 7106403 R 1246995 CDS YP_008737839.1 556569414 17447194 7107420..7109534 1 NC_022657.1 hypothetical protein 7109534 17447194 AFR_32640 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737839.1 7107420 D 1246995 CDS YP_008737840.1 556569415 17447195 7109626..7111209 1 NC_022657.1 COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; Cellulose synthesis regulatory protein 7111209 17447195 AFR_32645 Actinoplanes friuliensis DSM 7358 Cellulose synthesis regulatory protein YP_008737840.1 7109626 D 1246995 CDS YP_008737841.1 556569416 17447196 complement(7111204..7111983) 1 NC_022657.1 COG0708 Exonuclease III; endonuclease/exonuclease/phosphatase 7111983 17447196 AFR_32650 Actinoplanes friuliensis DSM 7358 endonuclease/exonuclease/phosphatase YP_008737841.1 7111204 R 1246995 CDS YP_008737842.1 556569417 17447197 complement(7111980..7113482) 1 NC_022657.1 COG0671 Membrane-associated phospholipid phosphatase; phosphoesterase pa-phosphatase-like protein 7113482 17447197 AFR_32655 Actinoplanes friuliensis DSM 7358 phosphoesterase pa-phosphatase-like protein YP_008737842.1 7111980 R 1246995 CDS YP_008737843.1 556569418 17447198 complement(7113520..7114557) 1 NC_022657.1 COG1295 Predicted membrane protein; putative ribonuclease BN 7114557 17447198 AFR_32660 Actinoplanes friuliensis DSM 7358 putative ribonuclease BN YP_008737843.1 7113520 R 1246995 CDS YP_008737844.1 556569419 17447199 complement(7114554..7115498) 1 NC_022657.1 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase; hypothetical protein 7115498 17447199 AFR_32665 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737844.1 7114554 R 1246995 CDS YP_008737845.1 556569420 17447200 7115631..7116461 1 NC_022657.1 hypothetical protein 7116461 17447200 AFR_32670 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737845.1 7115631 D 1246995 CDS YP_008737846.1 556569421 17447201 7116458..7116964 1 NC_022657.1 COG4762 Uncharacterized protein conserved in bacteria; hypothetical protein 7116964 17447201 AFR_32675 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737846.1 7116458 D 1246995 CDS YP_008737847.1 556569422 17447202 7116961..7117737 1 NC_022657.1 COG2220 Predicted Zn-dependent hydrolases of the beta-lactamase fold; hypothetical protein 7117737 17447202 AFR_32680 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737847.1 7116961 D 1246995 CDS YP_008737848.1 556569423 17447203 7117734..7118318 1 NC_022657.1 COG0586 Uncharacterized membrane-associated protein; hypothetical protein 7118318 17447203 AFR_32685 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737848.1 7117734 D 1246995 CDS YP_008737849.1 556569424 17447204 complement(7118315..7119253) 1 NC_022657.1 hypothetical protein 7119253 17447204 AFR_32690 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737849.1 7118315 R 1246995 CDS YP_008737850.1 556569425 17447205 7119354..7120112 1 NC_022657.1 hypothetical protein 7120112 17447205 AFR_32695 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737850.1 7119354 D 1246995 CDS YP_008737851.1 556569426 17447206 7120149..7121570 1 NC_022657.1 COG0642 Signal transduction histidine kinase; putative PAS-sensor signal transduction histidine kinase 7121570 17447206 AFR_32700 Actinoplanes friuliensis DSM 7358 putative PAS-sensor signal transduction histidine kinase YP_008737851.1 7120149 D 1246995 CDS YP_008737852.1 556569427 17447207 7121718..7124789 1 NC_022657.1 COG5498 Predicted glycosyl hydrolase; endo-1,3(4)-beta-glucanase 7124789 17447207 AFR_32705 Actinoplanes friuliensis DSM 7358 endo-1,3(4)-beta-glucanase YP_008737852.1 7121718 D 1246995 CDS YP_008737853.1 556569428 17447208 complement(7124815..7125798) 1 NC_022657.1 COG0515 Serine/threonine protein kinase; hypothetical protein 7125798 17447208 AFR_32710 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737853.1 7124815 R 1246995 CDS YP_008737854.1 556569429 17447209 complement(7125984..7127156) 1 NC_022657.1 COG2124 Cytochrome P450; cytochrome P450 7127156 17447209 AFR_32715 Actinoplanes friuliensis DSM 7358 cytochrome P450 YP_008737854.1 7125984 R 1246995 CDS YP_008737855.1 556569430 17447210 complement(7127254..7128297) 1 NC_022657.1 Streptogrisin-D 7128297 17447210 AFR_32720 Actinoplanes friuliensis DSM 7358 Streptogrisin-D YP_008737855.1 7127254 R 1246995 CDS YP_008737856.1 556569431 17447211 complement(7128477..7129646) 1 NC_022657.1 hypothetical protein 7129646 17447211 AFR_32725 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737856.1 7128477 R 1246995 CDS YP_008737857.1 556569432 17447212 complement(7131548..7132117) 1 NC_022657.1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; putative transcriptional regulator 7132117 17447212 AFR_32730 Actinoplanes friuliensis DSM 7358 putative transcriptional regulator YP_008737857.1 7131548 R 1246995 CDS YP_008737858.1 556569433 17447213 complement(7132477..7133571) 1 NC_022657.1 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases; alkanesulfonate monooxygenase 7133571 17447213 AFR_32735 Actinoplanes friuliensis DSM 7358 alkanesulfonate monooxygenase YP_008737858.1 7132477 R 1246995 CDS YP_008737859.1 556569434 17447214 complement(7133584..7134000) 1 NC_022657.1 COG4101 Predicted mannose-6-phosphate isomerase; cupin 7134000 17447214 AFR_32740 Actinoplanes friuliensis DSM 7358 cupin YP_008737859.1 7133584 R 1246995 CDS YP_008737860.1 556569435 17447215 complement(7133997..7136204) 1 NC_022657.1 COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Trimethylamine-N-oxide reductase (cytochrome c) 7136204 17447215 AFR_32745 Actinoplanes friuliensis DSM 7358 Trimethylamine-N-oxide reductase (cytochrome c) YP_008737860.1 7133997 R 1246995 CDS YP_008737861.1 556569436 17447216 complement(7136201..7136911) 1 NC_022657.1 COG1116 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component; Fe(3+)-transporting ATPase 7136911 17447216 AFR_32750 Actinoplanes friuliensis DSM 7358 Fe(3+)-transporting ATPase YP_008737861.1 7136201 R 1246995 CDS YP_008737862.1 556569437 17447217 complement(7136908..7137819) 1 NC_022657.1 COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components; NMT1/THI5 like domain-containing protein 7137819 17447217 AFR_32755 Actinoplanes friuliensis DSM 7358 NMT1/THI5 like domain-containing protein YP_008737862.1 7136908 R 1246995 CDS YP_008737863.1 556569438 17447218 complement(7137864..7138601) 1 NC_022657.1 COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component; sulfonate ABC transporter permease 7138601 17447218 AFR_32760 Actinoplanes friuliensis DSM 7358 sulfonate ABC transporter permease YP_008737863.1 7137864 R 1246995 CDS YP_008737864.1 556569439 17447219 7138884..7139993 1 NC_022657.1 COG1960 Acyl-CoA dehydrogenases; ccyl-CoA dehydrogenase type 2 domain-containing protein 7139993 17447219 AFR_32765 Actinoplanes friuliensis DSM 7358 ccyl-CoA dehydrogenase type 2 domain-containing protein YP_008737864.1 7138884 D 1246995 CDS YP_008737865.1 556569440 17447220 7139990..7141090 1 NC_022657.1 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases; alkanesulfonate monooxygenase 7141090 17447220 AFR_32770 Actinoplanes friuliensis DSM 7358 alkanesulfonate monooxygenase YP_008737865.1 7139990 D 1246995 CDS YP_008737866.1 556569441 17447221 7141101..7141616 1 NC_022657.1 COG1853 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family; putative flavin reductase 7141616 17447221 AFR_32775 Actinoplanes friuliensis DSM 7358 putative flavin reductase YP_008737866.1 7141101 D 1246995 CDS YP_008737867.1 556569442 17447222 7141617..7142678 1 NC_022657.1 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases; alkanesulfonate monooxygenase 7142678 17447222 AFR_32780 Actinoplanes friuliensis DSM 7358 alkanesulfonate monooxygenase YP_008737867.1 7141617 D 1246995 CDS YP_008737868.1 556569443 17447223 7142675..7143139 1 NC_022657.1 COG0431 Predicted flavoprotein; FMN-dependent NADH-azoreductase 7143139 17447223 AFR_32785 Actinoplanes friuliensis DSM 7358 FMN-dependent NADH-azoreductase YP_008737868.1 7142675 D 1246995 CDS YP_008737869.1 556569444 17447224 7143168..7143482 1 NC_022657.1 COG0222 Ribosomal protein L7/L12; hypothetical protein 7143482 17447224 AFR_32790 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737869.1 7143168 D 1246995 CDS YP_008737870.1 556569445 17447225 complement(7143561..7144277) 1 NC_022657.1 hypothetical protein 7144277 17447225 AFR_32795 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737870.1 7143561 R 1246995 CDS YP_008737871.1 556569446 17447226 complement(7144274..7144702) 1 NC_022657.1 hypothetical protein 7144702 17447226 AFR_32800 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737871.1 7144274 R 1246995 CDS YP_008737872.1 556569447 17447227 7144854..7145477 1 NC_022657.1 COG3647 Predicted membrane protein; hypothetical protein 7145477 17447227 AFR_32805 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737872.1 7144854 D 1246995 CDS YP_008737873.1 556569448 17447228 7145578..7147215 1 NC_022657.1 COG1457 Purine-cytosine permease and related proteins; hypothetical protein 7147215 17447228 AFR_32810 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737873.1 7145578 D 1246995 CDS YP_008737874.1 556569449 17447229 7147269..7147391 1 NC_022657.1 COG0257 Ribosomal protein L36; 50S ribosomal protein L36 7147391 rpmJ 17447229 rpmJ Actinoplanes friuliensis DSM 7358 50S ribosomal protein L36 YP_008737874.1 7147269 D 1246995 CDS YP_008737875.1 556569450 17447230 7147525..7148349 1 NC_022657.1 COG4757 Predicted alpha/beta hydrolase; alpha/beta hydrolase 7148349 17447230 AFR_32820 Actinoplanes friuliensis DSM 7358 alpha/beta hydrolase YP_008737875.1 7147525 D 1246995 CDS YP_008737876.1 556569451 17447231 complement(7148643..7149266) 1 NC_022657.1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; two component LuxR family transcriptional regulator 7149266 17447231 AFR_32825 Actinoplanes friuliensis DSM 7358 two component LuxR family transcriptional regulator YP_008737876.1 7148643 R 1246995 CDS YP_008737877.1 556569452 17447232 complement(7149263..7150558) 1 NC_022657.1 COG4585 Signal transduction histidine kinase; integral membrane sensor signal transduction histidine kinase 7150558 17447232 AFR_32830 Actinoplanes friuliensis DSM 7358 integral membrane sensor signal transduction histidine kinase YP_008737877.1 7149263 R 1246995 CDS YP_008737878.1 556569453 17447233 complement(7150560..7150988) 1 NC_022657.1 hypothetical protein 7150988 17447233 AFR_32835 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737878.1 7150560 R 1246995 CDS YP_008737879.1 556569454 17447234 complement(7151053..7152024) 1 NC_022657.1 hypothetical protein 7152024 17447234 AFR_32840 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737879.1 7151053 R 1246995 CDS YP_008737880.1 556569455 17447235 7152092..7153501 1 NC_022657.1 hypothetical protein 7153501 17447235 AFR_32845 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737880.1 7152092 D 1246995 CDS YP_008737881.1 556569456 17447236 complement(7153494..7154819) 1 NC_022657.1 COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases; FAD dependent oxidoreductase 7154819 17447236 AFR_32850 Actinoplanes friuliensis DSM 7358 FAD dependent oxidoreductase YP_008737881.1 7153494 R 1246995 CDS YP_008737882.1 556569457 17447237 7154895..7155464 1 NC_022657.1 COG2068 Uncharacterized MobA-related protein; hypothetical protein 7155464 17447237 AFR_32855 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737882.1 7154895 D 1246995 CDS YP_008737883.1 556569458 17447238 7155457..7156563 1 NC_022657.1 COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family; hypothetical protein 7156563 17447238 AFR_32860 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737883.1 7155457 D 1246995 CDS YP_008737884.1 556569459 17447239 7156605..7157666 1 NC_022657.1 COG0714 MoxR-like ATPases; ATPase 7157666 17447239 AFR_32865 Actinoplanes friuliensis DSM 7358 ATPase YP_008737884.1 7156605 D 1246995 CDS YP_008737885.1 556569460 17447240 7157632..7159464 1 NC_022657.1 COG3864 Uncharacterized protein conserved in bacteria; hypothetical protein 7159464 17447240 AFR_32870 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737885.1 7157632 D 1246995 CDS YP_008737886.1 556569461 17447241 complement(7159452..7160102) 1 NC_022657.1 COG1011 Predicted hydrolase (HAD superfamily); HAD-superfamily hydrolase 7160102 17447241 AFR_32875 Actinoplanes friuliensis DSM 7358 HAD-superfamily hydrolase YP_008737886.1 7159452 R 1246995 CDS YP_008737887.1 556569462 17447242 7160147..7161013 1 NC_022657.1 COG2515 1-aminocyclopropane-1-carboxylate deaminase; D-cysteine desulfhydrase 7161013 17447242 AFR_32880 Actinoplanes friuliensis DSM 7358 D-cysteine desulfhydrase YP_008737887.1 7160147 D 1246995 CDS YP_008737888.1 556569463 17447243 complement(7161024..7161932) 1 NC_022657.1 COG4977 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain; putative AdpA-family transcriptional regulator 7161932 17447243 AFR_32885 Actinoplanes friuliensis DSM 7358 putative AdpA-family transcriptional regulator YP_008737888.1 7161024 R 1246995 CDS YP_008737889.1 556569464 17447244 complement(7161929..7162525) 1 NC_022657.1 COG1335 Amidases related to nicotinamidase; isochorismatase hydrolase 7162525 17447244 AFR_32890 Actinoplanes friuliensis DSM 7358 isochorismatase hydrolase YP_008737889.1 7161929 R 1246995 CDS YP_008737890.1 556569465 17447245 7162659..7163366 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); 3-oxoacyl-ACP reductase 7163366 17447245 AFR_32895 Actinoplanes friuliensis DSM 7358 3-oxoacyl-ACP reductase YP_008737890.1 7162659 D 1246995 CDS YP_008737891.1 556569466 17447246 complement(7163373..7164797) 1 NC_022657.1 COG1073 Hydrolases of the alpha/beta superfamily; dienelactone hydrolase 7164797 17447246 AFR_32900 Actinoplanes friuliensis DSM 7358 dienelactone hydrolase YP_008737891.1 7163373 R 1246995 CDS YP_008737892.1 556569467 17447247 complement(7164876..7165811) 1 NC_022657.1 COG0524 Sugar kinases, ribokinase family; putative PfkB-family carbohydrate kinase 7165811 17447247 AFR_32905 Actinoplanes friuliensis DSM 7358 putative PfkB-family carbohydrate kinase YP_008737892.1 7164876 R 1246995 CDS YP_008737893.1 556569468 17447248 complement(7165808..7166437) 1 NC_022657.1 COG0800 2-keto-3-deoxy-6-phosphogluconate aldolase; 2-dehydro-3-deoxyphosphogluconate aldolase 7166437 17447248 AFR_32910 Actinoplanes friuliensis DSM 7358 2-dehydro-3-deoxyphosphogluconate aldolase YP_008737893.1 7165808 R 1246995 CDS YP_008737894.1 556569469 17447249 complement(7166495..7167004) 1 NC_022657.1 hypothetical protein 7167004 17447249 AFR_32915 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737894.1 7166495 R 1246995 CDS YP_008737895.1 556569470 17447250 complement(7167109..7167903) 1 NC_022657.1 putative AfsR-family transcriptional regulator 7167903 17447250 AFR_32920 Actinoplanes friuliensis DSM 7358 putative AfsR-family transcriptional regulator YP_008737895.1 7167109 R 1246995 CDS YP_008737896.1 556569471 17447251 7168093..7168989 1 NC_022657.1 COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases; putative alcohol dehydrogenase 7168989 17447251 AFR_32925 Actinoplanes friuliensis DSM 7358 putative alcohol dehydrogenase YP_008737896.1 7168093 D 1246995 CDS YP_008737897.1 556569472 17447252 complement(7168997..7171318) 1 NC_022657.1 COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain; putative signaling protein 7171318 17447252 AFR_32930 Actinoplanes friuliensis DSM 7358 putative signaling protein YP_008737897.1 7168997 R 1246995 CDS YP_008737898.1 556569473 17447253 7171502..7173589 1 NC_022657.1 COG5479 Uncharacterized protein potentially involved in peptidoglycan biosynthesis; putative N-acetylmuramoyl-L-alanine amidase 7173589 17447253 AFR_32935 Actinoplanes friuliensis DSM 7358 putative N-acetylmuramoyl-L-alanine amidase YP_008737898.1 7171502 D 1246995 CDS YP_008737899.1 556569474 17447254 complement(7173577..7174185) 1 NC_022657.1 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; RNA polymerase sigma factor SigL 7174185 17447254 AFR_32940 Actinoplanes friuliensis DSM 7358 RNA polymerase sigma factor SigL YP_008737899.1 7173577 R 1246995 CDS YP_008737900.1 556569475 17447255 7174343..7174570 1 NC_022657.1 hypothetical protein 7174570 17447255 AFR_32945 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737900.1 7174343 D 1246995 CDS YP_008737901.1 556569476 17447256 7174607..7176988 1 NC_022657.1 COG3903 Predicted ATPase; protein kinase 7176988 17447256 AFR_32950 Actinoplanes friuliensis DSM 7358 protein kinase YP_008737901.1 7174607 D 1246995 CDS YP_008737902.1 556569477 17447257 7177067..7177432 1 NC_022657.1 COG2764 Uncharacterized protein conserved in bacteria; hypothetical protein 7177432 17447257 AFR_32955 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737902.1 7177067 D 1246995 CDS YP_008737903.1 556569478 17447258 7177500..7178090 1 NC_022657.1 COG0640 Predicted transcriptional regulators; putative transcriptional regulator 7178090 17447258 AFR_32960 Actinoplanes friuliensis DSM 7358 putative transcriptional regulator YP_008737903.1 7177500 D 1246995 CDS YP_008737904.1 556569479 17447259 7178092..7179339 1 NC_022657.1 COG0477 Permeases of the major facilitator superfamily; major facilitator superfamily protein 7179339 17447259 AFR_32965 Actinoplanes friuliensis DSM 7358 major facilitator superfamily protein YP_008737904.1 7178092 D 1246995 CDS YP_008737905.1 556569480 17447260 7179468..7179839 1 NC_022657.1 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; putative NUDIX hydrolase 7179839 17447260 AFR_32970 Actinoplanes friuliensis DSM 7358 putative NUDIX hydrolase YP_008737905.1 7179468 D 1246995 CDS YP_008737906.1 556569481 17447261 complement(7179832..7180314) 1 NC_022657.1 COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog); hypothetical protein 7180314 17447261 AFR_32975 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737906.1 7179832 R 1246995 CDS YP_008737907.1 556569482 17447262 complement(7180311..7181102) 1 NC_022657.1 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases; hypothetical protein 7181102 17447262 AFR_32980 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737907.1 7180311 R 1246995 CDS YP_008737908.1 556569483 17447263 7181106..7181657 1 NC_022657.1 COG1309 Transcriptional regulator; Fatty acid metabolism regulator protein 7181657 17447263 AFR_32985 Actinoplanes friuliensis DSM 7358 Fatty acid metabolism regulator protein YP_008737908.1 7181106 D 1246995 CDS YP_008737909.1 556569484 17447264 complement(7181636..7182187) 1 NC_022657.1 COG1309 Transcriptional regulator; tetracycline repressor 7182187 17447264 AFR_32990 Actinoplanes friuliensis DSM 7358 tetracycline repressor YP_008737909.1 7181636 R 1246995 CDS YP_008737910.1 556569485 17447265 7182334..7183941 1 NC_022657.1 COG2936 Predicted acyl esterases; hydrolase 7183941 17447265 AFR_32995 Actinoplanes friuliensis DSM 7358 hydrolase YP_008737910.1 7182334 D 1246995 CDS YP_008737911.1 556569486 17447266 7184002..7184148 1 NC_022657.1 hypothetical protein 7184148 17447266 AFR_33000 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737911.1 7184002 D 1246995 CDS YP_008737912.1 556569487 17447267 complement(7184138..7185835) 1 NC_022657.1 COG0366 Glycosidases; oligo-1,6-glucosidase 7185835 17447267 AFR_33005 Actinoplanes friuliensis DSM 7358 oligo-1,6-glucosidase YP_008737912.1 7184138 R 1246995 CDS YP_008737913.1 556569488 17447268 7185897..7186898 1 NC_022657.1 COG0438 Glycosyltransferase; Glycogen synthase 2 7186898 17447268 AFR_33010 Actinoplanes friuliensis DSM 7358 Glycogen synthase 2 YP_008737913.1 7185897 D 1246995 CDS YP_008737914.1 556569489 17447269 7187042..7188193 1 NC_022657.1 COG0438 Glycosyltransferase; group 1 glycosyl transferase 7188193 17447269 AFR_33015 Actinoplanes friuliensis DSM 7358 group 1 glycosyl transferase YP_008737914.1 7187042 D 1246995 CDS YP_008737915.1 556569490 17447270 7188202..7189272 1 NC_022657.1 putative glycosyltransferase 7189272 17447270 AFR_33020 Actinoplanes friuliensis DSM 7358 putative glycosyltransferase YP_008737915.1 7188202 D 1246995 CDS YP_008737916.1 556569491 17447271 7189269..7190774 1 NC_022657.1 COG2152 Predicted glycosylase; glycosidase 7190774 17447271 AFR_33025 Actinoplanes friuliensis DSM 7358 glycosidase YP_008737916.1 7189269 D 1246995 CDS YP_008737917.1 556569492 17447272 complement(7190771..7191445) 1 NC_022657.1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; LuxR family two component transcriptional regulator 7191445 17447272 AFR_33030 Actinoplanes friuliensis DSM 7358 LuxR family two component transcriptional regulator YP_008737917.1 7190771 R 1246995 CDS YP_008737918.1 556569493 17447273 7191475..7192581 1 NC_022657.1 COG2706 3-carboxymuconate cyclase; hypothetical protein 7192581 17447273 AFR_33035 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737918.1 7191475 D 1246995 CDS YP_008737919.1 556569494 17447274 complement(7192746..7193852) 1 NC_022657.1 COG3851 Signal transduction histidine kinase, glucose-6-phosphate specific; histidine kinase 7193852 17447274 AFR_33040 Actinoplanes friuliensis DSM 7358 histidine kinase YP_008737919.1 7192746 R 1246995 CDS YP_008737920.1 556569495 17447275 7194017..7194652 1 NC_022657.1 hypothetical protein 7194652 17447275 AFR_33045 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737920.1 7194017 D 1246995 CDS YP_008737921.1 556569496 17447276 complement(7194813..7195634) 1 NC_022657.1 COG2226 Methylase involved in ubiquinone/menaquinone biosynthesis; hypothetical protein 7195634 17447276 AFR_33050 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737921.1 7194813 R 1246995 CDS YP_008737922.1 556569497 17447277 7195734..7197182 1 NC_022657.1 COG2199 FOG: GGDEF domain; hypothetical protein 7197182 17447277 AFR_33055 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737922.1 7195734 D 1246995 CDS YP_008737923.1 556569498 17447278 7197186..7199438 1 NC_022657.1 COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain; diguanylate cyclase/phosphodiesterase 7199438 17447278 AFR_33060 Actinoplanes friuliensis DSM 7358 diguanylate cyclase/phosphodiesterase YP_008737923.1 7197186 D 1246995 CDS YP_008737924.1 556569499 17447279 7199449..7200468 1 NC_022657.1 COG0673 Predicted dehydrogenases and related proteins; putative oxidoreductase 7200468 17447279 AFR_33065 Actinoplanes friuliensis DSM 7358 putative oxidoreductase YP_008737924.1 7199449 D 1246995 CDS YP_008737925.1 556569500 17447280 complement(7200458..7201273) 1 NC_022657.1 COG0702 Predicted nucleoside-diphosphate-sugar epimerases; hypothetical protein 7201273 17447280 AFR_33070 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737925.1 7200458 R 1246995 CDS YP_008737926.1 556569501 17447281 complement(7201283..7202269) 1 NC_022657.1 COG1228 Imidazolonepropionase and related amidohydrolases; putative amidohydrolase 7202269 17447281 AFR_33075 Actinoplanes friuliensis DSM 7358 putative amidohydrolase YP_008737926.1 7201283 R 1246995 CDS YP_008737927.1 556569502 17447282 complement(7202266..7203495) 1 NC_022657.1 COG3844 Kynureninase; putative kynureninase 7203495 17447282 AFR_33080 Actinoplanes friuliensis DSM 7358 putative kynureninase YP_008737927.1 7202266 R 1246995 CDS YP_008737928.1 556569503 17447283 complement(7203492..7204349) 1 NC_022657.1 COG3483 Tryptophan 2,3-dioxygenase (vermilion); tryptophan 2,3-dioxygenase 7204349 17447283 AFR_33085 Actinoplanes friuliensis DSM 7358 tryptophan 2,3-dioxygenase YP_008737928.1 7203492 R 1246995 CDS YP_008737929.1 556569504 17447284 complement(7204393..7204794) 1 NC_022657.1 COG3012 Uncharacterized protein conserved in bacteria; hypothetical protein 7204794 17447284 AFR_33090 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737929.1 7204393 R 1246995 CDS YP_008737930.1 556569505 17447285 complement(7204799..7205173) 1 NC_022657.1 COG0789 Predicted transcriptional regulators; regulatory protein MerR 7205173 17447285 AFR_33095 Actinoplanes friuliensis DSM 7358 regulatory protein MerR YP_008737930.1 7204799 R 1246995 CDS YP_008737931.1 556569506 17447286 7205228..7206157 1 NC_022657.1 COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases); aldo/keto reductase 7206157 17447286 AFR_33100 Actinoplanes friuliensis DSM 7358 aldo/keto reductase YP_008737931.1 7205228 D 1246995 CDS YP_008737932.1 556569507 17447287 complement(7206161..7206628) 1 NC_022657.1 COG0840 Methyl-accepting chemotaxis protein; putative methyl-accepting chemotaxis protein 7206628 17447287 AFR_33105 Actinoplanes friuliensis DSM 7358 putative methyl-accepting chemotaxis protein YP_008737932.1 7206161 R 1246995 CDS YP_008737933.1 556569508 17447288 7207275..7207418 1 NC_022657.1 COG0861 Membrane protein TerC, possibly involved in tellurium resistance; hypothetical protein 7207418 17447288 AFR_33110 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737933.1 7207275 D 1246995 CDS YP_008737934.1 556569509 17447289 7207554..7208336 1 NC_022657.1 COG1396 Predicted transcriptional regulators; helix-turn-helix domain-containing protein 7208336 17447289 AFR_33115 Actinoplanes friuliensis DSM 7358 helix-turn-helix domain-containing protein YP_008737934.1 7207554 D 1246995 CDS YP_008737935.1 556569510 17447290 7208582..7209604 1 NC_022657.1 COG1609 Transcriptional regulators; LacI family transcriptional regulator 7209604 17447290 AFR_33120 Actinoplanes friuliensis DSM 7358 LacI family transcriptional regulator YP_008737935.1 7208582 D 1246995 CDS YP_008737936.1 556569511 17447291 7209824..7211185 1 NC_022657.1 COG1653 ABC-type sugar transport system, periplasmic component; sugar ABC transporter periplasmic protein 7211185 17447291 AFR_33125 Actinoplanes friuliensis DSM 7358 sugar ABC transporter periplasmic protein YP_008737936.1 7209824 D 1246995 CDS YP_008737937.1 556569512 17447292 7211244..7212158 1 NC_022657.1 COG1175 ABC-type sugar transport systems, permease components; sugar ABC transporter permease 7212158 17447292 AFR_33130 Actinoplanes friuliensis DSM 7358 sugar ABC transporter permease YP_008737937.1 7211244 D 1246995 CDS YP_008737938.1 556569513 17447293 7212169..7213137 1 NC_022657.1 COG0395 ABC-type sugar transport system, permease component; sugar transporter intracellular portion 7213137 17447293 AFR_33135 Actinoplanes friuliensis DSM 7358 sugar transporter intracellular portion YP_008737938.1 7212169 D 1246995 CDS YP_008737939.1 556569514 17447294 7213183..7214829 1 NC_022657.1 COG0366 Glycosidases; alpha amylase 7214829 17447294 AFR_33140 Actinoplanes friuliensis DSM 7358 alpha amylase YP_008737939.1 7213183 D 1246995 CDS YP_008737940.1 556569515 17447295 7214891..7217608 1 NC_022657.1 COG5434 Endopolygalacturonase; coagulation factor 5/8 type domain-containing protein 7217608 17447295 AFR_33145 Actinoplanes friuliensis DSM 7358 coagulation factor 5/8 type domain-containing protein YP_008737940.1 7214891 D 1246995 CDS YP_008737941.1 556569516 17447296 7217690..7221529 1 NC_022657.1 COG1572 Uncharacterized conserved protein; APHP domain-containing protein 7221529 17447296 AFR_33150 Actinoplanes friuliensis DSM 7358 APHP domain-containing protein YP_008737941.1 7217690 D 1246995 CDS YP_008737942.1 556569517 17447297 complement(7221592..7222236) 1 NC_022657.1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; response regulator receiver protein 7222236 17447297 AFR_33155 Actinoplanes friuliensis DSM 7358 response regulator receiver protein YP_008737942.1 7221592 R 1246995 CDS YP_008737943.1 556569518 17447298 complement(7222233..7223327) 1 NC_022657.1 COG4585 Signal transduction histidine kinase; signal transduction histidine kinase-like protein 7223327 17447298 AFR_33160 Actinoplanes friuliensis DSM 7358 signal transduction histidine kinase-like protein YP_008737943.1 7222233 R 1246995 CDS YP_008737944.1 556569519 17447299 complement(7223397..7223627) 1 NC_022657.1 hypothetical protein 7223627 17447299 AFR_33165 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737944.1 7223397 R 1246995 CDS YP_008737945.1 556569520 17447300 complement(7223795..7225909) 1 NC_022657.1 COG0659 Sulfate permease and related transporters (MFS superfamily); putative sulfate transporter and carbonic anhidrase 7225909 17447300 AFR_33170 Actinoplanes friuliensis DSM 7358 putative sulfate transporter and carbonic anhidrase YP_008737945.1 7223795 R 1246995 CDS YP_008737946.1 556569521 17447301 complement(7226818..7227513) 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); short-chain dehydrogenase/reductase SDR 7227513 17447301 AFR_33175 Actinoplanes friuliensis DSM 7358 short-chain dehydrogenase/reductase SDR YP_008737946.1 7226818 R 1246995 CDS YP_008737947.1 556569522 17447302 complement(7227590..7230271) 1 NC_022657.1 COG0574 Phosphoenolpyruvate synthase/pyruvate phosphate dikinase; pyruvate phosphate dikinase 7230271 17447302 AFR_33180 Actinoplanes friuliensis DSM 7358 pyruvate phosphate dikinase YP_008737947.1 7227590 R 1246995 CDS YP_008737948.1 556569523 17447303 7230588..7233182 1 NC_022657.1 COG2170 Uncharacterized conserved protein; Carboxylate-amine ligase 7233182 17447303 AFR_33185 Actinoplanes friuliensis DSM 7358 Carboxylate-amine ligase YP_008737948.1 7230588 D 1246995 CDS YP_008737949.1 556569524 17447304 7233277..7235049 1 NC_022657.1 COG0367 Asparagine synthase (glutamine-hydrolyzing); asparagine synthase 7235049 17447304 AFR_33190 Actinoplanes friuliensis DSM 7358 asparagine synthase YP_008737949.1 7233277 D 1246995 CDS YP_008737950.1 556569525 17447305 7235070..7236866 1 NC_022657.1 COG0823 Periplasmic component of the Tol biopolymer transport system; yuxL-like peptidase 7236866 17447305 AFR_33195 Actinoplanes friuliensis DSM 7358 yuxL-like peptidase YP_008737950.1 7235070 D 1246995 CDS YP_008737951.1 556569526 17447306 7236972..7238261 1 NC_022657.1 COG0477 Permeases of the major facilitator superfamily; putative glucarate transporter 7238261 17447306 AFR_33200 Actinoplanes friuliensis DSM 7358 putative glucarate transporter YP_008737951.1 7236972 D 1246995 CDS YP_008737952.1 556569527 17447307 7238300..7239052 1 NC_022657.1 hypothetical protein 7239052 17447307 AFR_33205 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737952.1 7238300 D 1246995 CDS YP_008737953.1 556569528 17447308 7239081..7239584 1 NC_022657.1 hypothetical protein 7239584 17447308 AFR_33210 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737953.1 7239081 D 1246995 CDS YP_008737954.1 556569529 17447309 complement(7239654..7242713) 1 NC_022657.1 COG2310 Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1; hypothetical protein 7242713 17447309 AFR_33215 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737954.1 7239654 R 1246995 CDS YP_008737955.1 556569530 17447310 complement(7242872..7244347) 1 NC_022657.1 COG0642 Signal transduction histidine kinase; histidine kinase 7244347 17447310 AFR_33220 Actinoplanes friuliensis DSM 7358 histidine kinase YP_008737955.1 7242872 R 1246995 CDS YP_008737956.1 556569531 17447311 complement(7244347..7246005) 1 NC_022657.1 COG0784 FOG: CheY-like receiver; putative thioredoxin reductase 7246005 17447311 AFR_33225 Actinoplanes friuliensis DSM 7358 putative thioredoxin reductase YP_008737956.1 7244347 R 1246995 CDS YP_008737957.1 556569532 17447312 complement(7246016..7246309) 1 NC_022657.1 COG5207 Isopeptidase T; Zn-finger-containing protein 7246309 17447312 AFR_33230 Actinoplanes friuliensis DSM 7358 Zn-finger-containing protein YP_008737957.1 7246016 R 1246995 CDS YP_008737958.1 556569533 17447313 complement(7246306..7247469) 1 NC_022657.1 COG0061 Predicted sugar kinase; NAD+ kinase 7247469 17447313 AFR_33235 Actinoplanes friuliensis DSM 7358 NAD+ kinase YP_008737958.1 7246306 R 1246995 CDS YP_008737959.1 556569534 17447314 complement(7247566..7248300) 1 NC_022657.1 COG3897 Predicted methyltransferase; hypothetical protein 7248300 17447314 AFR_33240 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737959.1 7247566 R 1246995 CDS YP_008737960.1 556569535 17447315 complement(7248386..7248589) 1 NC_022657.1 COG1278 Cold shock proteins; CspA family cold shock protein 7248589 17447315 AFR_33245 Actinoplanes friuliensis DSM 7358 CspA family cold shock protein YP_008737960.1 7248386 R 1246995 CDS YP_008737961.1 556569536 17447316 7248895..7250442 1 NC_022657.1 ricin b lectin 7250442 17447316 AFR_33250 Actinoplanes friuliensis DSM 7358 ricin b lectin YP_008737961.1 7248895 D 1246995 CDS YP_008737962.1 556569537 17447317 7250627..7252255 1 NC_022657.1 hypothetical protein 7252255 17447317 AFR_33255 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737962.1 7250627 D 1246995 CDS YP_008737963.1 556569538 17447318 7252477..7253760 1 NC_022657.1 COG0477 Permeases of the major facilitator superfamily; MFS transporter, DHA1 family, bicyclomycin/chloramphenicol resistance protein 7253760 17447318 AFR_33260 Actinoplanes friuliensis DSM 7358 MFS transporter, DHA1 family, bicyclomycin/chloramphenicol resistance protein YP_008737963.1 7252477 D 1246995 CDS YP_008737964.1 556569539 17447319 7253832..7254638 1 NC_022657.1 COG2339 Predicted membrane protein; hypothetical protein 7254638 17447319 AFR_33265 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737964.1 7253832 D 1246995 CDS YP_008737965.1 556569540 17447320 complement(7254703..7255581) 1 NC_022657.1 COG2375 Siderophore-interacting protein; Siderophore-interacting protein 7255581 17447320 AFR_33270 Actinoplanes friuliensis DSM 7358 Siderophore-interacting protein YP_008737965.1 7254703 R 1246995 CDS YP_008737966.1 556569541 17447321 complement(7255628..7256647) 1 NC_022657.1 LuxR family transcriptional regulator fused with ATPase domain 7256647 17447321 AFR_33275 Actinoplanes friuliensis DSM 7358 LuxR family transcriptional regulator fused with ATPase domain YP_008737966.1 7255628 R 1246995 CDS YP_008737967.1 556569542 17447322 7256845..7257681 1 NC_022657.1 COG3001 Fructosamine-3-kinase; putative phosphotransferase 7257681 17447322 AFR_33280 Actinoplanes friuliensis DSM 7358 putative phosphotransferase YP_008737967.1 7256845 D 1246995 CDS YP_008737968.1 556569543 17447323 7257740..7258138 1 NC_022657.1 COG0789 Predicted transcriptional regulators; putative MerR-family transcriptional regulator 7258138 17447323 AFR_33285 Actinoplanes friuliensis DSM 7358 putative MerR-family transcriptional regulator YP_008737968.1 7257740 D 1246995 CDS YP_008737969.1 556569544 17447324 7258135..7258944 1 NC_022657.1 COG0725 ABC-type molybdate transport system, periplasmic component; molybdenum ABC transporter periplasmic substrate-binding protein 7258944 17447324 AFR_33290 Actinoplanes friuliensis DSM 7358 molybdenum ABC transporter periplasmic substrate-binding protein YP_008737969.1 7258135 D 1246995 CDS YP_008737970.1 556569545 17447325 7259058..7259735 1 NC_022657.1 COG4149 ABC-type molybdate transport system, permease component; molybdate ABC transporter, inner membrane subunit 7259735 17447325 AFR_33295 Actinoplanes friuliensis DSM 7358 molybdate ABC transporter, inner membrane subunit YP_008737970.1 7259058 D 1246995 CDS YP_008737971.1 556569546 17447326 7259732..7260784 1 NC_022657.1 COG1118 ABC-type sulfate/molybdate transport systems, ATPase component; ABC transporter 7260784 17447326 AFR_33300 Actinoplanes friuliensis DSM 7358 ABC transporter YP_008737971.1 7259732 D 1246995 CDS YP_008737972.1 556569547 17447327 complement(7261538..7263223) 1 NC_022657.1 hypothetical protein 7263223 17447327 AFR_33305 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737972.1 7261538 R 1246995 CDS YP_008737973.1 556569548 17447328 complement(7263349..7266993) 1 NC_022657.1 alpha-L-rhamnosidase 7266993 17447328 AFR_33310 Actinoplanes friuliensis DSM 7358 alpha-L-rhamnosidase YP_008737973.1 7263349 R 1246995 CDS YP_008737974.1 556569549 17447329 7267115..7267702 1 NC_022657.1 COG3358 Uncharacterized conserved protein; hypothetical protein 7267702 17447329 AFR_33315 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737974.1 7267115 D 1246995 CDS YP_008737975.1 556569550 17447330 7267758..7268660 1 NC_022657.1 hypothetical protein 7268660 17447330 AFR_33320 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737975.1 7267758 D 1246995 CDS YP_008737976.1 556569551 17447331 7268629..7269669 1 NC_022657.1 COG1064 Zn-dependent alcohol dehydrogenases; alcohol dehydrogenase GroES domain-containing protein 7269669 17447331 AFR_33325 Actinoplanes friuliensis DSM 7358 alcohol dehydrogenase GroES domain-containing protein YP_008737976.1 7268629 D 1246995 CDS YP_008737977.1 556569552 17447332 7269754..7270887 1 NC_022657.1 COG4585 Signal transduction histidine kinase; two-component system sensor kinase 7270887 17447332 AFR_33330 Actinoplanes friuliensis DSM 7358 two-component system sensor kinase YP_008737977.1 7269754 D 1246995 CDS YP_008737978.1 556569553 17447333 7270884..7271537 1 NC_022657.1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; response regulator receiver protein 7271537 17447333 AFR_33335 Actinoplanes friuliensis DSM 7358 response regulator receiver protein YP_008737978.1 7270884 D 1246995 CDS YP_008737979.1 556569554 17447334 7271613..7272422 1 NC_022657.1 hypothetical protein 7272422 17447334 AFR_33340 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737979.1 7271613 D 1246995 CDS YP_008737980.1 556569555 17447335 complement(7272428..7272976) 1 NC_022657.1 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins; putative GCN5-related N-acetyltransferase 7272976 17447335 AFR_33345 Actinoplanes friuliensis DSM 7358 putative GCN5-related N-acetyltransferase YP_008737980.1 7272428 R 1246995 CDS YP_008737981.1 556569556 17447336 7273788..7274066 1 NC_022657.1 hypothetical protein 7274066 17447336 AFR_33350 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737981.1 7273788 D 1246995 CDS YP_008737982.1 556569557 17447337 complement(7274181..7274351) 1 NC_022657.1 hypothetical protein 7274351 17447337 AFR_33355 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737982.1 7274181 R 1246995 CDS YP_008737983.1 556569558 17447338 complement(7274332..7275159) 1 NC_022657.1 hypothetical protein 7275159 17447338 AFR_33360 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737983.1 7274332 R 1246995 CDS YP_008737984.1 556569559 17447339 7275201..7275659 1 NC_022657.1 COG0539 Ribosomal protein S1; 30S ribosomal protein S1 7275659 rpsA 17447339 rpsA Actinoplanes friuliensis DSM 7358 30S ribosomal protein S1 YP_008737984.1 7275201 D 1246995 CDS YP_008737985.1 556569560 17447340 complement(7275917..7277086) 1 NC_022657.1 COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase; putative glycosyltransferase 7277086 17447340 AFR_33370 Actinoplanes friuliensis DSM 7358 putative glycosyltransferase YP_008737985.1 7275917 R 1246995 CDS YP_008737986.1 556569561 17447341 7277194..7277718 1 NC_022657.1 COG1309 Transcriptional regulator; putative TetR-family transcriptional regulator 7277718 17447341 AFR_33375 Actinoplanes friuliensis DSM 7358 putative TetR-family transcriptional regulator YP_008737986.1 7277194 D 1246995 CDS YP_008737987.1 556569562 17447342 complement(7277719..7278225) 1 NC_022657.1 COG0312 Predicted Zn-dependent proteases and their inactivated homologs; hypothetical protein 7278225 17447342 AFR_33380 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737987.1 7277719 R 1246995 CDS YP_008737988.1 556569563 17447343 complement(7278233..7280446) 1 NC_022657.1 hypothetical protein 7280446 17447343 AFR_33385 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737988.1 7278233 R 1246995 CDS YP_008737989.1 556569564 17447344 complement(7280443..7281129) 1 NC_022657.1 COG1136 ABC-type antimicrobial peptide transport system, ATPase component; ABC transporter 7281129 17447344 AFR_33390 Actinoplanes friuliensis DSM 7358 ABC transporter YP_008737989.1 7280443 R 1246995 CDS YP_008737990.1 556569565 17447345 complement(7281126..7281650) 1 NC_022657.1 COG1695 Predicted transcriptional regulators; putative PadR family transcriptional regulator 7281650 17447345 AFR_33395 Actinoplanes friuliensis DSM 7358 putative PadR family transcriptional regulator YP_008737990.1 7281126 R 1246995 CDS YP_008737991.1 556569566 17447346 7281747..7282070 1 NC_022657.1 COG0640 Predicted transcriptional regulators; ArsR family transcriptional regulator 7282070 17447346 AFR_33400 Actinoplanes friuliensis DSM 7358 ArsR family transcriptional regulator YP_008737991.1 7281747 D 1246995 CDS YP_008737992.1 556569567 17447347 7282115..7282471 1 NC_022657.1 COG3832 Uncharacterized conserved protein; Activator of Hsp90 ATPase 1 family protein 7282471 17447347 AFR_33405 Actinoplanes friuliensis DSM 7358 Activator of Hsp90 ATPase 1 family protein YP_008737992.1 7282115 D 1246995 CDS YP_008737993.1 556569568 17447348 7282480..7283232 1 NC_022657.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); hydrolase 7283232 17447348 AFR_33410 Actinoplanes friuliensis DSM 7358 hydrolase YP_008737993.1 7282480 D 1246995 CDS YP_008737994.1 556569569 17447349 complement(7283252..7284649) 1 NC_022657.1 COG0001 Glutamate-1-semialdehyde aminotransferase; hypothetical protein 7284649 17447349 AFR_33415 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737994.1 7283252 R 1246995 CDS YP_008737995.1 556569570 17447350 7284821..7286125 1 NC_022657.1 COG0457 FOG: TPR repeat; hypothetical protein 7286125 17447350 AFR_33420 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737995.1 7284821 D 1246995 CDS YP_008737996.1 556569571 17447351 7286122..7288353 1 NC_022657.1 COG2215 ABC-type uncharacterized transport system, permease component; hypothetical protein 7288353 17447351 AFR_33425 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008737996.1 7286122 D 1246995 CDS YP_008737997.1 556569572 17447352 7288369..7291479 1 NC_022657.1 signal transduction protein with Nacht domain 7291479 17447352 AFR_33430 Actinoplanes friuliensis DSM 7358 signal transduction protein with Nacht domain YP_008737997.1 7288369 D 1246995 CDS YP_008737998.1 556569573 17447353 7291568..7292161 1 NC_022657.1 COG1309 Transcriptional regulator; TetR family transcriptional regulator 7292161 17447353 AFR_33435 Actinoplanes friuliensis DSM 7358 TetR family transcriptional regulator YP_008737998.1 7291568 D 1246995 CDS YP_008737999.1 556569574 17447354 7292216..7293901 1 NC_022657.1 COG1132 ABC-type multidrug transport system, ATPase and permease components; Lipid A export ATP-binding/permease protein msbA 7293901 17447354 AFR_33440 Actinoplanes friuliensis DSM 7358 Lipid A export ATP-binding/permease protein msbA YP_008737999.1 7292216 D 1246995 CDS YP_008738000.1 556569575 17447355 7293952..7295856 1 NC_022657.1 COG1132 ABC-type multidrug transport system, ATPase and permease components; putative ABC transporter ATPase and permease protein 7295856 17447355 AFR_33445 Actinoplanes friuliensis DSM 7358 putative ABC transporter ATPase and permease protein YP_008738000.1 7293952 D 1246995 CDS YP_008738001.1 556569576 17447356 complement(7295913..7298798) 1 NC_022657.1 hypothetical protein 7298798 17447356 AFR_33450 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738001.1 7295913 R 1246995 CDS YP_008738002.1 556569577 17447357 complement(7299265..7300479) 1 NC_022657.1 hypothetical protein 7300479 17447357 AFR_33455 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738002.1 7299265 R 1246995 CDS YP_008738003.1 556569578 17447358 7300522..7300848 1 NC_022657.1 hypothetical protein 7300848 17447358 AFR_33460 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738003.1 7300522 D 1246995 CDS YP_008738004.1 556569579 17447359 7300989..7302311 1 NC_022657.1 COG1785 Alkaline phosphatase; alkaline phosphatase 7302311 17447359 AFR_33465 Actinoplanes friuliensis DSM 7358 alkaline phosphatase YP_008738004.1 7300989 D 1246995 CDS YP_008738005.1 556569580 17447360 complement(7302352..7303773) 1 NC_022657.1 COG2148 Sugar transferases involved in lipopolysaccharide synthesis; putative glycosyltransferase 7303773 17447360 AFR_33470 Actinoplanes friuliensis DSM 7358 putative glycosyltransferase YP_008738005.1 7302352 R 1246995 CDS YP_008738006.1 556569581 17447361 complement(7304370..7304591) 1 NC_022657.1 COG1141 Ferredoxin; ferredoxin 7304591 17447361 AFR_33475 Actinoplanes friuliensis DSM 7358 ferredoxin YP_008738006.1 7304370 R 1246995 CDS YP_008738007.1 556569582 17447362 complement(7304588..7305796) 1 NC_022657.1 COG1894 NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit; NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit 7305796 17447362 AFR_33480 Actinoplanes friuliensis DSM 7358 NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit YP_008738007.1 7304588 R 1246995 CDS YP_008738008.1 556569583 17447363 complement(7305793..7306377) 1 NC_022657.1 COG2717 Predicted membrane protein; putative ferric reductase 7306377 17447363 AFR_33485 Actinoplanes friuliensis DSM 7358 putative ferric reductase YP_008738008.1 7305793 R 1246995 CDS YP_008738009.1 556569584 17447364 complement(7306365..7307279) 1 NC_022657.1 COG1477 Membrane-associated lipoprotein involved in thiamine biosynthesis; ApbE-like thiamine biosynthesis lipoprotein 7307279 17447364 AFR_33490 Actinoplanes friuliensis DSM 7358 ApbE-like thiamine biosynthesis lipoprotein YP_008738009.1 7306365 R 1246995 CDS YP_008738010.1 556569585 17447365 complement(7307281..7307544) 1 NC_022657.1 hypothetical protein 7307544 17447365 AFR_33495 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738010.1 7307281 R 1246995 CDS YP_008738011.1 556569586 17447366 7307691..7310411 1 NC_022657.1 COG2771 DNA-binding HTH domain-containing proteins; putative LuxR-family transcriptional regulator 7310411 17447366 AFR_33500 Actinoplanes friuliensis DSM 7358 putative LuxR-family transcriptional regulator YP_008738011.1 7307691 D 1246995 CDS YP_008738012.1 556569587 17447367 7310473..7311336 1 NC_022657.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); hypothetical protein 7311336 17447367 AFR_33505 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738012.1 7310473 D 1246995 CDS YP_008738013.1 556569588 17447368 complement(7311333..7311950) 1 NC_022657.1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; transcriptional regulatory protein degU 7311950 17447368 AFR_33510 Actinoplanes friuliensis DSM 7358 transcriptional regulatory protein degU YP_008738013.1 7311333 R 1246995 CDS YP_008738014.1 556569589 17447369 complement(7311947..7313074) 1 NC_022657.1 COG4585 Signal transduction histidine kinase; histidine kinase 7313074 17447369 AFR_33515 Actinoplanes friuliensis DSM 7358 histidine kinase YP_008738014.1 7311947 R 1246995 CDS YP_008738015.1 556569590 17447370 complement(7313071..7313871) 1 NC_022657.1 COG0842 ABC-type multidrug transport system, permease component; Pleiotropic drug resistance protein 3 7313871 17447370 AFR_33520 Actinoplanes friuliensis DSM 7358 Pleiotropic drug resistance protein 3 YP_008738015.1 7313071 R 1246995 CDS YP_008738016.1 556569591 17447371 complement(7313868..7314704) 1 NC_022657.1 COG1131 ABC-type multidrug transport system, ATPase component; spermidine/putrescine import ATP-binding protein potA 7314704 17447371 AFR_33525 Actinoplanes friuliensis DSM 7358 spermidine/putrescine import ATP-binding protein potA YP_008738016.1 7313868 R 1246995 CDS YP_008738017.1 556569592 17447372 complement(7314906..7315673) 1 NC_022657.1 COG0842 ABC-type multidrug transport system, permease component; antibiotic transport system permease 7315673 17447372 AFR_33530 Actinoplanes friuliensis DSM 7358 antibiotic transport system permease YP_008738017.1 7314906 R 1246995 CDS YP_008738018.1 556569593 17447373 complement(7315670..7316584) 1 NC_022657.1 COG1131 ABC-type multidrug transport system, ATPase component; spermidine/putrescine import ATP-binding protein potA 7316584 17447373 AFR_33535 Actinoplanes friuliensis DSM 7358 spermidine/putrescine import ATP-binding protein potA YP_008738018.1 7315670 R 1246995 CDS YP_008738019.1 556569594 17447374 7316819..7317259 1 NC_022657.1 COG0328 Ribonuclease HI; ribonuclease H 7317259 17447374 AFR_33540 Actinoplanes friuliensis DSM 7358 ribonuclease H YP_008738019.1 7316819 D 1246995 CDS YP_008738020.1 556569595 17447375 7317327..7317767 1 NC_022657.1 hypothetical protein 7317767 17447375 AFR_33545 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738020.1 7317327 D 1246995 CDS YP_008738021.1 556569596 17447376 7317764..7319287 1 NC_022657.1 COG2132 Putative multicopper oxidases; bilirubin oxidase 7319287 17447376 AFR_33550 Actinoplanes friuliensis DSM 7358 bilirubin oxidase YP_008738021.1 7317764 D 1246995 CDS YP_008738022.1 556569597 17447377 complement(7319288..7319719) 1 NC_022657.1 COG1846 Transcriptional regulators; transcriptional regulator slyA 7319719 17447377 AFR_33555 Actinoplanes friuliensis DSM 7358 transcriptional regulator slyA YP_008738022.1 7319288 R 1246995 CDS YP_008738023.1 556569598 17447378 7319817..7320317 1 NC_022657.1 hypothetical protein 7320317 17447378 AFR_33560 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738023.1 7319817 D 1246995 CDS YP_008738024.1 556569599 17447379 7320340..7321131 1 NC_022657.1 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases; luciferase-like monooxygenase 7321131 17447379 AFR_33565 Actinoplanes friuliensis DSM 7358 luciferase-like monooxygenase YP_008738024.1 7320340 D 1246995 CDS YP_008738025.1 556569600 17447380 7321128..7322225 1 NC_022657.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); epoxide hydrolase domain-containing protein 7322225 17447380 AFR_33570 Actinoplanes friuliensis DSM 7358 epoxide hydrolase domain-containing protein YP_008738025.1 7321128 D 1246995 CDS YP_008738026.1 556569601 17447381 7322238..7322738 1 NC_022657.1 COG2128 Uncharacterized conserved protein; putative carboxymuconolactone decarboxylase 7322738 17447381 AFR_33575 Actinoplanes friuliensis DSM 7358 putative carboxymuconolactone decarboxylase YP_008738026.1 7322238 D 1246995 CDS YP_008738027.1 556569602 17447382 7323747..7324490 1 NC_022657.1 COG2154 Pterin-4a-carbinolamine dehydratase; 4a-hydroxytetrahydrobiopterin dehydratase 7324490 17447382 AFR_33580 Actinoplanes friuliensis DSM 7358 4a-hydroxytetrahydrobiopterin dehydratase YP_008738027.1 7323747 D 1246995 CDS YP_008738028.1 556569603 17447383 complement(7324502..7324855) 1 NC_022657.1 COG3801 Uncharacterized protein conserved in bacteria; hypothetical protein 7324855 17447383 AFR_33585 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738028.1 7324502 R 1246995 CDS YP_008738029.1 556569604 17447384 complement(7324894..7325766) 1 NC_022657.1 hypothetical protein 7325766 17447384 AFR_33590 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738029.1 7324894 R 1246995 CDS YP_008738030.1 556569605 17447385 complement(7325799..7328573) 1 NC_022657.1 COG3899 Predicted ATPase; Fimbriae Z protein 7328573 17447385 AFR_33595 Actinoplanes friuliensis DSM 7358 Fimbriae Z protein YP_008738030.1 7325799 R 1246995 CDS YP_008738031.1 556569606 17447386 7328686..7328934 1 NC_022657.1 hypothetical protein 7328934 17447386 AFR_33600 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738031.1 7328686 D 1246995 CDS YP_008738032.1 556569607 17447387 complement(7328931..7329806) 1 NC_022657.1 COG3485 Protocatechuate 3,4-dioxygenase beta subunit; putative dioxygenase 7329806 17447387 AFR_33605 Actinoplanes friuliensis DSM 7358 putative dioxygenase YP_008738032.1 7328931 R 1246995 CDS YP_008738033.1 556569608 17447388 7329929..7330744 1 NC_022657.1 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases; dehydrogenase 7330744 17447388 AFR_33610 Actinoplanes friuliensis DSM 7358 dehydrogenase YP_008738033.1 7329929 D 1246995 CDS YP_008738034.1 556569609 17447389 7330791..7331342 1 NC_022657.1 COG0640 Predicted transcriptional regulators; regulatory protein ArsR 7331342 17447389 AFR_33615 Actinoplanes friuliensis DSM 7358 regulatory protein ArsR YP_008738034.1 7330791 D 1246995 CDS YP_008738035.1 556569610 17447390 7331369..7332601 1 NC_022657.1 COG0477 Permeases of the major facilitator superfamily; hypothetical protein 7332601 17447390 AFR_33620 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738035.1 7331369 D 1246995 CDS YP_008738036.1 556569611 17447391 complement(7332604..7333821) 1 NC_022657.1 COG0641 Arylsulfatase regulator (Fe-S oxidoreductase); Anaerobic sulfatase-maturating enzyme 7333821 17447391 AFR_33625 Actinoplanes friuliensis DSM 7358 Anaerobic sulfatase-maturating enzyme YP_008738036.1 7332604 R 1246995 CDS YP_008738037.1 556569612 17447392 complement(7333880..7334914) 1 NC_022657.1 COG0789 Predicted transcriptional regulators; regulatory protein 7334914 17447392 AFR_33630 Actinoplanes friuliensis DSM 7358 regulatory protein YP_008738037.1 7333880 R 1246995 CDS YP_008738038.1 556569613 17447393 complement(7334997..7336097) 1 NC_022657.1 COG1835 Predicted acyltransferases; putative acyltransferase 7336097 17447393 AFR_33635 Actinoplanes friuliensis DSM 7358 putative acyltransferase YP_008738038.1 7334997 R 1246995 CDS YP_008738039.1 556569614 17447394 7336334..7337356 1 NC_022657.1 COG1609 Transcriptional regulators; LacI family transcriptional regulator 7337356 17447394 AFR_33640 Actinoplanes friuliensis DSM 7358 LacI family transcriptional regulator YP_008738039.1 7336334 D 1246995 CDS YP_008738040.1 556569615 17447395 7337436..7337789 1 NC_022657.1 hypothetical protein 7337789 17447395 AFR_33645 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738040.1 7337436 D 1246995 CDS YP_008738041.1 556569616 17447396 7337794..7338750 1 NC_022657.1 COG3285 Predicted eukaryotic-type DNA primase; hypothetical protein 7338750 17447396 AFR_33650 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738041.1 7337794 D 1246995 CDS YP_008738042.1 556569617 17447397 complement(7338911..7339426) 1 NC_022657.1 hypothetical protein 7339426 17447397 AFR_33655 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738042.1 7338911 R 1246995 CDS YP_008738043.1 556569618 17447398 7339608..7340729 1 NC_022657.1 COG4585 Signal transduction histidine kinase; putative two-component system sensor kinase 7340729 17447398 AFR_33660 Actinoplanes friuliensis DSM 7358 putative two-component system sensor kinase YP_008738043.1 7339608 D 1246995 CDS YP_008738044.1 556569619 17447399 7340731..7341414 1 NC_022657.1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; putative two-component system response regulator 7341414 17447399 AFR_33665 Actinoplanes friuliensis DSM 7358 putative two-component system response regulator YP_008738044.1 7340731 D 1246995 CDS YP_008738045.1 556569620 17447400 complement(7341394..7342329) 1 NC_022657.1 hypothetical protein 7342329 17447400 AFR_33670 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738045.1 7341394 R 1246995 CDS YP_008738046.1 556569621 17447401 7342620..7346852 1 NC_022657.1 COG3537 Putative alpha-1,2-mannosidase; alpha-1,2-mannosidase 7346852 17447401 AFR_33675 Actinoplanes friuliensis DSM 7358 alpha-1,2-mannosidase YP_008738046.1 7342620 D 1246995 CDS YP_008738047.1 556569622 17447402 7346927..7347364 1 NC_022657.1 F420-dependent protein 7347364 17447402 AFR_33680 Actinoplanes friuliensis DSM 7358 F420-dependent protein YP_008738047.1 7346927 D 1246995 CDS YP_008738048.1 556569623 17447403 7347368..7347733 1 NC_022657.1 hypothetical protein 7347733 17447403 AFR_33685 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738048.1 7347368 D 1246995 CDS YP_008738049.1 556569624 17447404 complement(7347730..7350852) 1 NC_022657.1 COG0542 ATPases with chaperone activity, ATP-binding subunit; hypothetical protein 7350852 17447404 AFR_33690 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738049.1 7347730 R 1246995 CDS YP_008738050.1 556569625 17447405 complement(7350875..7354117) 1 NC_022657.1 COG3537 Putative alpha-1,2-mannosidase; alpha-1,2-mannosidase 7354117 17447405 AFR_33695 Actinoplanes friuliensis DSM 7358 alpha-1,2-mannosidase YP_008738050.1 7350875 R 1246995 CDS YP_008738051.1 556569626 17447406 7354309..7357092 1 NC_022657.1 COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain; putative diguanylate cyclase/phosphodiesterase with PAS sensor 7357092 17447406 AFR_33700 Actinoplanes friuliensis DSM 7358 putative diguanylate cyclase/phosphodiesterase with PAS sensor YP_008738051.1 7354309 D 1246995 CDS YP_008738052.1 556569627 17447407 7357133..7358377 1 NC_022657.1 COG0019 Diaminopimelate decarboxylase; ornithine decarboxylase 7358377 17447407 AFR_33705 Actinoplanes friuliensis DSM 7358 ornithine decarboxylase YP_008738052.1 7357133 D 1246995 CDS YP_008738053.1 556569628 17447408 7358367..7359680 1 NC_022657.1 COG0477 Permeases of the major facilitator superfamily; hypothetical protein 7359680 17447408 AFR_33710 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738053.1 7358367 D 1246995 CDS YP_008738054.1 556569629 17447409 complement(7359669..7360214) 1 NC_022657.1 hypothetical protein 7360214 17447409 AFR_33715 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738054.1 7359669 R 1246995 CDS YP_008738055.1 556569630 17447410 7360357..7361442 1 NC_022657.1 peptidase alpha-lytic pro domain-containing protein 7361442 17447410 AFR_33720 Actinoplanes friuliensis DSM 7358 peptidase alpha-lytic pro domain-containing protein YP_008738055.1 7360357 D 1246995 CDS YP_008738056.1 556569631 17447411 7361474..7362124 1 NC_022657.1 hypothetical protein 7362124 17447411 AFR_33725 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738056.1 7361474 D 1246995 CDS YP_008738057.1 556569632 17447412 7362233..7362724 1 NC_022657.1 hypothetical protein 7362724 17447412 AFR_33730 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738057.1 7362233 D 1246995 CDS YP_008738058.1 556569633 17447413 complement(7362739..7363218) 1 NC_022657.1 COG0500 SAM-dependent methyltransferases; hypothetical protein 7363218 17447413 AFR_33735 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738058.1 7362739 R 1246995 CDS YP_008738059.1 556569634 17447414 complement(7363480..7365027) 1 NC_022657.1 COG0308 Aminopeptidase N; metallopeptidase 7365027 17447414 AFR_33740 Actinoplanes friuliensis DSM 7358 metallopeptidase YP_008738059.1 7363480 R 1246995 CDS YP_008738060.1 556569635 17447415 complement(7365136..7365984) 1 NC_022657.1 COG1801 Uncharacterized conserved protein; hypothetical protein 7365984 17447415 AFR_33745 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738060.1 7365136 R 1246995 CDS YP_008738061.1 556569636 17447416 complement(7365981..7366550) 1 NC_022657.1 COG0640 Predicted transcriptional regulators; ArsR family transcriptional regulator 7366550 17447416 AFR_33750 Actinoplanes friuliensis DSM 7358 ArsR family transcriptional regulator YP_008738061.1 7365981 R 1246995 CDS YP_008738062.1 556569637 17447417 7366606..7367172 1 NC_022657.1 COG0412 Dienelactone hydrolase and related enzymes; dienelactone hydrolase 7367172 17447417 AFR_33755 Actinoplanes friuliensis DSM 7358 dienelactone hydrolase YP_008738062.1 7366606 D 1246995 CDS YP_008738063.1 556569638 17447418 complement(7367169..7367513) 1 NC_022657.1 hypothetical protein 7367513 17447418 AFR_33760 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738063.1 7367169 R 1246995 CDS YP_008738064.1 556569639 17447419 complement(7367751..7368530) 1 NC_022657.1 COG3752 Predicted membrane protein; hypothetical protein 7368530 17447419 AFR_33765 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738064.1 7367751 R 1246995 CDS YP_008738065.1 556569640 17447420 complement(7368527..7369798) 1 NC_022657.1 COG2230 Cyclopropane fatty acid synthase and related methyltransferases; cyclopropane fatty acid synthase 7369798 17447420 AFR_33770 Actinoplanes friuliensis DSM 7358 cyclopropane fatty acid synthase YP_008738065.1 7368527 R 1246995 CDS YP_008738066.1 556569641 17447421 complement(7369795..7371033) 1 NC_022657.1 COG2230 Cyclopropane fatty acid synthase and related methyltransferases; cyclopropane fatty acid synthase 7371033 17447421 AFR_33775 Actinoplanes friuliensis DSM 7358 cyclopropane fatty acid synthase YP_008738066.1 7369795 R 1246995 CDS YP_008738067.1 556569642 17447422 complement(7371030..7371704) 1 NC_022657.1 COG3496 Uncharacterized conserved protein; hypothetical protein 7371704 17447422 AFR_33780 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738067.1 7371030 R 1246995 CDS YP_008738068.1 556569643 17447423 complement(7371701..7373026) 1 NC_022657.1 COG2907 Predicted NAD/FAD-binding protein; amine oxidase 7373026 17447423 AFR_33785 Actinoplanes friuliensis DSM 7358 amine oxidase YP_008738068.1 7371701 R 1246995 CDS YP_008738069.1 556569644 17447424 7373061..7373675 1 NC_022657.1 COG2267 Lysophospholipase; hypothetical protein 7373675 17447424 AFR_33790 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738069.1 7373061 D 1246995 CDS YP_008738070.1 556569645 17447425 7374064..7375767 1 NC_022657.1 COG2273 Beta-glucanase/Beta-glucan synthetase; coagulation factor 5/8 type domain-containing protein 7375767 17447425 AFR_33795 Actinoplanes friuliensis DSM 7358 coagulation factor 5/8 type domain-containing protein YP_008738070.1 7374064 D 1246995 CDS YP_008738071.1 556569646 17447426 7375867..7377138 1 NC_022657.1 COG3291 FOG: PKD repeat; hypothetical protein 7377138 17447426 AFR_33800 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738071.1 7375867 D 1246995 CDS YP_008738072.1 556569647 17447427 7377278..7378285 1 NC_022657.1 COG1609 Transcriptional regulators; putative LacI-family transcriptional regulator 7378285 17447427 AFR_33805 Actinoplanes friuliensis DSM 7358 putative LacI-family transcriptional regulator YP_008738072.1 7377278 D 1246995 CDS YP_008738073.1 556569648 17447428 7378319..7379038 1 NC_022657.1 hypothetical protein 7379038 17447428 AFR_33810 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738073.1 7378319 D 1246995 CDS YP_008738074.1 556569649 17447429 7379049..7379690 1 NC_022657.1 COG0702 Predicted nucleoside-diphosphate-sugar epimerases; hypothetical protein 7379690 17447429 AFR_33815 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738074.1 7379049 D 1246995 CDS YP_008738075.1 556569650 17447430 complement(7379687..7380958) 1 NC_022657.1 hypothetical protein 7380958 17447430 AFR_33820 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738075.1 7379687 R 1246995 CDS YP_008738076.1 556569651 17447431 complement(7380972..7381877) 1 NC_022657.1 hypothetical protein 7381877 17447431 AFR_33825 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738076.1 7380972 R 1246995 CDS YP_008738077.1 556569652 17447432 7381933..7382643 1 NC_022657.1 COG0457 FOG: TPR repeat; hypothetical protein 7382643 17447432 AFR_33830 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738077.1 7381933 D 1246995 CDS YP_008738078.1 556569653 17447433 7382630..7383067 1 NC_022657.1 hypothetical protein 7383067 17447433 AFR_33835 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738078.1 7382630 D 1246995 CDS YP_008738079.1 556569654 17447434 complement(7383064..7383429) 1 NC_022657.1 COG0789 Predicted transcriptional regulators; MerR family transcriptional regulator 7383429 17447434 AFR_33840 Actinoplanes friuliensis DSM 7358 MerR family transcriptional regulator YP_008738079.1 7383064 R 1246995 CDS YP_008738080.1 556569655 17447435 complement(7383426..7383710) 1 NC_022657.1 hypothetical protein 7383710 17447435 AFR_33845 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738080.1 7383426 R 1246995 CDS YP_008738081.1 556569656 17447436 complement(7383812..7384669) 1 NC_022657.1 COG1105 Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB); PfkB domain-containing protein 7384669 17447436 AFR_33850 Actinoplanes friuliensis DSM 7358 PfkB domain-containing protein YP_008738081.1 7383812 R 1246995 CDS YP_008738082.1 556569657 17447437 complement(7384666..7385508) 1 NC_022657.1 COG0524 Sugar kinases, ribokinase family; ribokinase-like domain-containing protein 7385508 17447437 AFR_33855 Actinoplanes friuliensis DSM 7358 ribokinase-like domain-containing protein YP_008738082.1 7384666 R 1246995 CDS YP_008738083.1 556569658 17447438 complement(7385520..7386365) 1 NC_022657.1 COG1830 DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes; Fructose-bisphosphate aldolase 7386365 17447438 AFR_33860 Actinoplanes friuliensis DSM 7358 Fructose-bisphosphate aldolase YP_008738083.1 7385520 R 1246995 CDS YP_008738084.1 556569659 17447439 complement(7386390..7387385) 1 NC_022657.1 COG1879 ABC-type sugar transport system, periplasmic component; twin-arginine translocation pathway signal protein 7387385 17447439 AFR_33865 Actinoplanes friuliensis DSM 7358 twin-arginine translocation pathway signal protein YP_008738084.1 7386390 R 1246995 CDS YP_008738085.1 556569660 17447440 complement(7387409..7388404) 1 NC_022657.1 COG4158 Predicted ABC-type sugar transport system, permease component; monosaccharide-transporting ATPase 7388404 17447440 AFR_33870 Actinoplanes friuliensis DSM 7358 monosaccharide-transporting ATPase YP_008738085.1 7387409 R 1246995 CDS YP_008738086.1 556569661 17447441 complement(7388401..7389168) 1 NC_022657.1 COG1129 ABC-type sugar transport system, ATPase component; ABC transporter 7389168 17447441 AFR_33875 Actinoplanes friuliensis DSM 7358 ABC transporter YP_008738086.1 7388401 R 1246995 CDS YP_008738087.1 556569662 17447442 7389367..7390761 1 NC_022657.1 COG0277 FAD/FMN-containing dehydrogenases; FAD linked oxidase domain-containing protein 7390761 17447442 AFR_33880 Actinoplanes friuliensis DSM 7358 FAD linked oxidase domain-containing protein YP_008738087.1 7389367 D 1246995 CDS YP_008738088.1 556569663 17447443 7390770..7391699 1 NC_022657.1 hypothetical protein 7391699 17447443 AFR_33885 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738088.1 7390770 D 1246995 CDS YP_008738089.1 556569664 17447444 complement(7391704..7392657) 1 NC_022657.1 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; hypothetical protein 7392657 17447444 AFR_33890 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738089.1 7391704 R 1246995 CDS YP_008738090.1 556569665 17447445 7392968..7393858 1 NC_022657.1 hypothetical protein 7393858 17447445 AFR_33895 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738090.1 7392968 D 1246995 CDS YP_008738091.1 556569666 17447446 7393911..7394852 1 NC_022657.1 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases; putative luciferase-like monooxygenase 7394852 17447446 AFR_33900 Actinoplanes friuliensis DSM 7358 putative luciferase-like monooxygenase YP_008738091.1 7393911 D 1246995 CDS YP_008738092.1 556569667 17447447 7394961..7395494 1 NC_022657.1 hypothetical protein 7395494 17447447 AFR_33905 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738092.1 7394961 D 1246995 CDS YP_008738093.1 556569668 17447448 complement(7395548..7396738) 1 NC_022657.1 glucan endo-1,3-beta-D-glucosidase 7396738 17447448 AFR_33910 Actinoplanes friuliensis DSM 7358 glucan endo-1,3-beta-D-glucosidase YP_008738093.1 7395548 R 1246995 CDS YP_008738094.1 556569669 17447449 7397136..7397804 1 NC_022657.1 carbohydrate binding family 6 7397804 17447449 AFR_33915 Actinoplanes friuliensis DSM 7358 carbohydrate binding family 6 YP_008738094.1 7397136 D 1246995 CDS YP_008738095.1 556569670 17447450 complement(7397853..7398239) 1 NC_022657.1 COG0071 Molecular chaperone (small heat shock protein); 18.5 kDa class I heat shock protein 7398239 17447450 AFR_33920 Actinoplanes friuliensis DSM 7358 18.5 kDa class I heat shock protein YP_008738095.1 7397853 R 1246995 CDS YP_008738096.1 556569671 17447451 complement(7398346..7398762) 1 NC_022657.1 COG3542 Uncharacterized conserved protein; hypothetical protein 7398762 17447451 AFR_33925 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738096.1 7398346 R 1246995 CDS YP_008738097.1 556569672 17447452 7398815..7400005 1 NC_022657.1 COG0389 Nucleotidyltransferase/DNA polymerase involved in DNA repair; DNA polymerase IV 7400005 17447452 AFR_33930 Actinoplanes friuliensis DSM 7358 DNA polymerase IV YP_008738097.1 7398815 D 1246995 CDS YP_008738098.1 556569673 17447453 complement(7400002..7400310) 1 NC_022657.1 hypothetical protein 7400310 17447453 AFR_33935 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738098.1 7400002 R 1246995 CDS YP_008738099.1 556569674 17447454 7400444..7402639 1 NC_022657.1 COG4564 Signal transduction histidine kinase; two-component system histidine kinase 7402639 17447454 AFR_33940 Actinoplanes friuliensis DSM 7358 two-component system histidine kinase YP_008738099.1 7400444 D 1246995 CDS YP_008738100.1 556569675 17447455 7402640..7403281 1 NC_022657.1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; two-component system response regulator 7403281 17447455 AFR_33945 Actinoplanes friuliensis DSM 7358 two-component system response regulator YP_008738100.1 7402640 D 1246995 CDS YP_008738101.1 556569676 17447456 complement(7403389..7404624) 1 NC_022657.1 hypothetical protein 7404624 17447456 AFR_33950 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738101.1 7403389 R 1246995 CDS YP_008738102.1 556569677 17447457 7404710..7405822 1 NC_022657.1 COG1940 Transcriptional regulator/sugar kinase; ROK family transcriptional regulator 7405822 17447457 AFR_33955 Actinoplanes friuliensis DSM 7358 ROK family transcriptional regulator YP_008738102.1 7404710 D 1246995 CDS YP_008738103.1 556569678 17447458 7406461..7406916 1 NC_022657.1 COG0222 Ribosomal protein L7/L12; hypothetical protein 7406916 17447458 AFR_33960 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738103.1 7406461 D 1246995 CDS YP_008738104.1 556569679 17447459 7406961..7407719 1 NC_022657.1 COG2243 Precorrin-2 methylase; precorrin 6A synthase 7407719 17447459 AFR_33965 Actinoplanes friuliensis DSM 7358 precorrin 6A synthase YP_008738104.1 7406961 D 1246995 CDS YP_008738105.1 556569680 17447460 complement(7407699..7408529) 1 NC_022657.1 hypothetical protein 7408529 17447460 AFR_33970 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738105.1 7407699 R 1246995 CDS YP_008738106.1 556569681 17447461 complement(7408649..7412197) 1 NC_022657.1 COG1429 Cobalamin biosynthesis protein CobN and related Mg-chelatases; cobaltochelatase subunit CobN 7412197 cobN 17447461 cobN Actinoplanes friuliensis DSM 7358 cobaltochelatase subunit CobN YP_008738106.1 7408649 R 1246995 CDS YP_008738107.1 556569682 17447462 7412504..7413658 1 NC_022657.1 COG0155 Sulfite reductase, beta subunit (hemoprotein); precorrin-3B synthase 7413658 17447462 AFR_33980 Actinoplanes friuliensis DSM 7358 precorrin-3B synthase YP_008738107.1 7412504 D 1246995 CDS YP_008738108.1 556569683 17447463 7413660..7414277 1 NC_022657.1 COG2082 Precorrin isomerase; precorrin-8X methylmutase 7414277 17447463 AFR_33985 Actinoplanes friuliensis DSM 7358 precorrin-8X methylmutase YP_008738108.1 7413660 D 1246995 CDS YP_008738109.1 556569684 17447464 7414279..7415790 1 NC_022657.1 COG2243 Precorrin-2 methylase; putative precorrin methylase 7415790 17447464 AFR_33990 Actinoplanes friuliensis DSM 7358 putative precorrin methylase YP_008738109.1 7414279 D 1246995 CDS YP_008738110.1 556569685 17447465 complement(7415753..7416496) 1 NC_022657.1 COG2099 Precorrin-6x reductase; precorrin-6x reductase 7416496 17447465 AFR_33995 Actinoplanes friuliensis DSM 7358 precorrin-6x reductase YP_008738110.1 7415753 R 1246995 CDS YP_008738111.1 556569686 17447466 complement(7416493..7417236) 1 NC_022657.1 COG2875 Precorrin-4 methylase; putative methyltransferase 7417236 17447466 AFR_34000 Actinoplanes friuliensis DSM 7358 putative methyltransferase YP_008738111.1 7416493 R 1246995 CDS YP_008738112.1 556569687 17447467 complement(7417233..7418447) 1 NC_022657.1 COG2241 Precorrin-6B methylase 1; precorrin-6Y C5,15-methyltransferase / precorrin-8W decarboxylase 7418447 17447467 AFR_34005 Actinoplanes friuliensis DSM 7358 precorrin-6Y C5,15-methyltransferase / precorrin-8W decarboxylase YP_008738112.1 7417233 R 1246995 CDS YP_008738113.1 556569688 17447468 7418680..7420188 1 NC_022657.1 COG4097 Predicted ferric reductase; Respiratory burst oxidase-like protein 7420188 17447468 AFR_34010 Actinoplanes friuliensis DSM 7358 Respiratory burst oxidase-like protein YP_008738113.1 7418680 D 1246995 CDS YP_008738114.1 556569689 17447469 7420228..7420749 1 NC_022657.1 COG3976 Uncharacterized protein conserved in bacteria; hypothetical protein 7420749 17447469 AFR_34015 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738114.1 7420228 D 1246995 CDS YP_008738115.1 556569690 17447470 7420761..7421510 1 NC_022657.1 COG1477 Membrane-associated lipoprotein involved in thiamine biosynthesis; hypothetical protein 7421510 17447470 AFR_34020 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738115.1 7420761 D 1246995 CDS YP_008738116.1 556569691 17447471 complement(7421529..7422719) 1 NC_022657.1 COG4552 Predicted acetyltransferase involved in intracellular survival and related acetyltransferases; hypothetical protein 7422719 17447471 AFR_34025 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738116.1 7421529 R 1246995 CDS YP_008738117.1 556569692 17447475 complement(7423317..7423673) 1 NC_022657.1 COG0582 Integrase; LacI family transcriptional regulator 7423673 17447475 AFR_34030 Actinoplanes friuliensis DSM 7358 LacI family transcriptional regulator YP_008738117.1 7423317 R 1246995 CDS YP_008738118.1 556569693 17447476 7424064..7424303 1 NC_022657.1 hypothetical protein 7424303 17447476 AFR_34035 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738118.1 7424064 D 1246995 CDS YP_008738119.1 556569694 17447477 complement(7429026..7429985) 1 NC_022657.1 COG1357 Uncharacterized low-complexity proteins; hypothetical protein 7429985 17447477 AFR_34040 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738119.1 7429026 R 1246995 CDS YP_008738120.1 556569695 17447479 7434019..7434684 1 NC_022657.1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; two-component system response regulator 7434684 17447479 AFR_34045 Actinoplanes friuliensis DSM 7358 two-component system response regulator YP_008738120.1 7434019 D 1246995 CDS YP_008738121.1 556569696 17447480 complement(7434695..7435861) 1 NC_022657.1 hypothetical protein 7435861 17447480 AFR_34050 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738121.1 7434695 R 1246995 CDS YP_008738122.1 556569697 17447481 7436125..7438224 1 NC_022657.1 COG2409 Predicted drug exporters of the RND superfamily; putative integral membrane protein 7438224 17447481 AFR_34055 Actinoplanes friuliensis DSM 7358 putative integral membrane protein YP_008738122.1 7436125 D 1246995 CDS YP_008738123.1 556569698 17447482 7438401..7438871 1 NC_022657.1 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; putative GCN5-related N-acetyltransferase 7438871 17447482 AFR_34060 Actinoplanes friuliensis DSM 7358 putative GCN5-related N-acetyltransferase YP_008738123.1 7438401 D 1246995 CDS YP_008738124.1 556569699 17447483 7438959..7441265 1 NC_022657.1 COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; putative molybdopterin oxidoreductase 7441265 17447483 AFR_34065 Actinoplanes friuliensis DSM 7358 putative molybdopterin oxidoreductase YP_008738124.1 7438959 D 1246995 CDS YP_008738125.1 556569700 17447484 7441262..7441726 1 NC_022657.1 hypothetical protein 7441726 17447484 AFR_34070 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738125.1 7441262 D 1246995 CDS YP_008738126.1 556569701 17447485 7441807..7443330 1 NC_022657.1 COG1404 Subtilisin-like serine proteases; peptidase S8 and S53 subtilisin kexin sedolisin 7443330 17447485 AFR_34075 Actinoplanes friuliensis DSM 7358 peptidase S8 and S53 subtilisin kexin sedolisin YP_008738126.1 7441807 D 1246995 CDS YP_008738127.1 556569702 17447486 7443425..7444126 1 NC_022657.1 hypothetical protein 7444126 17447486 AFR_34080 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738127.1 7443425 D 1246995 CDS YP_008738128.1 556569703 17447487 complement(7444127..7444591) 1 NC_022657.1 hypothetical protein 7444591 17447487 AFR_34085 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738128.1 7444127 R 1246995 CDS YP_008738129.1 556569704 17447488 complement(7444595..7444873) 1 NC_022657.1 hypothetical protein 7444873 17447488 AFR_34090 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738129.1 7444595 R 1246995 CDS YP_008738130.1 556569705 17447489 complement(7444929..7446143) 1 NC_022657.1 COG1376 Uncharacterized protein conserved in bacteria; hypothetical protein 7446143 17447489 AFR_34095 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738130.1 7444929 R 1246995 CDS YP_008738131.1 556569706 17447490 complement(7446414..7447007) 1 NC_022657.1 hypothetical protein 7447007 17447490 AFR_34100 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738131.1 7446414 R 1246995 CDS YP_008738132.1 556569707 17447491 7447384..7447884 1 NC_022657.1 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; ECF subfamily RNA polymerase sigma-24 subunit 7447884 17447491 AFR_34105 Actinoplanes friuliensis DSM 7358 ECF subfamily RNA polymerase sigma-24 subunit YP_008738132.1 7447384 D 1246995 CDS YP_008738133.1 556569708 17447492 7447881..7448732 1 NC_022657.1 hypothetical protein 7448732 17447492 AFR_34110 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738133.1 7447881 D 1246995 CDS YP_008738134.1 556569709 17447493 7448799..7449530 1 NC_022657.1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; two component response regulator 7449530 17447493 AFR_34115 Actinoplanes friuliensis DSM 7358 two component response regulator YP_008738134.1 7448799 D 1246995 CDS YP_008738135.1 556569710 17447494 7449527..7450939 1 NC_022657.1 COG0642 Signal transduction histidine kinase; putative two component sensor kinase 7450939 17447494 AFR_34120 Actinoplanes friuliensis DSM 7358 putative two component sensor kinase YP_008738135.1 7449527 D 1246995 CDS YP_008738136.1 556569711 17447495 complement(7450946..7451650) 1 NC_022657.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); esterase 7451650 17447495 AFR_34125 Actinoplanes friuliensis DSM 7358 esterase YP_008738136.1 7450946 R 1246995 CDS YP_008738137.1 556569712 17447496 7451760..7452098 1 NC_022657.1 COG1733 Predicted transcriptional regulators; hypothetical protein 7452098 17447496 AFR_34130 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738137.1 7451760 D 1246995 CDS YP_008738138.1 556569713 17447497 complement(7452102..7453640) 1 NC_022657.1 T-cell immunomodulatory-like protein 7453640 17447497 AFR_34135 Actinoplanes friuliensis DSM 7358 T-cell immunomodulatory-like protein YP_008738138.1 7452102 R 1246995 CDS YP_008738139.1 556569714 17447498 complement(7453759..7454754) 1 NC_022657.1 COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; glyceraldehyde-3-phosphate dehydrogenase 7454754 17447498 AFR_34140 Actinoplanes friuliensis DSM 7358 glyceraldehyde-3-phosphate dehydrogenase YP_008738139.1 7453759 R 1246995 CDS YP_008738140.1 556569715 17447499 complement(7454833..7455753) 1 NC_022657.1 COG4977 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain; AraC family transcriptional regulator 7455753 17447499 AFR_34145 Actinoplanes friuliensis DSM 7358 AraC family transcriptional regulator YP_008738140.1 7454833 R 1246995 CDS YP_008738141.1 556569716 17447500 7455822..7456421 1 NC_022657.1 hypothetical protein 7456421 17447500 AFR_34150 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738141.1 7455822 D 1246995 CDS YP_008738142.1 556569717 17447501 complement(7456431..7458719) 1 NC_022657.1 COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain; Protein gmr 7458719 17447501 AFR_34155 Actinoplanes friuliensis DSM 7358 Protein gmr YP_008738142.1 7456431 R 1246995 CDS YP_008738143.1 556569718 17447502 7458912..7459115 1 NC_022657.1 hypothetical protein 7459115 17447502 AFR_34160 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738143.1 7458912 D 1246995 CDS YP_008738144.1 556569719 17447503 7459112..7461820 1 NC_022657.1 COG3899 Predicted ATPase; putative LuxR-family transcriptional regulator 7461820 17447503 AFR_34165 Actinoplanes friuliensis DSM 7358 putative LuxR-family transcriptional regulator YP_008738144.1 7459112 D 1246995 CDS YP_008738145.1 556569720 17447504 7461817..7463286 1 NC_022657.1 hypothetical protein 7463286 17447504 AFR_34170 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738145.1 7461817 D 1246995 CDS YP_008738146.1 556569721 17447505 7463318..7466299 1 NC_022657.1 COG1501 Alpha-glucosidases, family 31 of glycosyl hydrolases; glycoside hydrolase family protein 7466299 17447505 AFR_34175 Actinoplanes friuliensis DSM 7358 glycoside hydrolase family protein YP_008738146.1 7463318 D 1246995 CDS YP_008738147.1 556569722 17447506 7466457..7467365 1 NC_022657.1 COG1131 ABC-type multidrug transport system, ATPase component; ABC transporter 7467365 17447506 AFR_34180 Actinoplanes friuliensis DSM 7358 ABC transporter YP_008738147.1 7466457 D 1246995 CDS YP_008738148.1 556569723 17447507 7467395..7468129 1 NC_022657.1 COG0842 ABC-type multidrug transport system, permease component; ABC transporter permease 7468129 17447507 AFR_34185 Actinoplanes friuliensis DSM 7358 ABC transporter permease YP_008738148.1 7467395 D 1246995 CDS YP_008738149.1 556569724 17447508 7468141..7469376 1 NC_022657.1 COG4585 Signal transduction histidine kinase; histidine kinase 7469376 17447508 AFR_34190 Actinoplanes friuliensis DSM 7358 histidine kinase YP_008738149.1 7468141 D 1246995 CDS YP_008738150.1 556569725 17447509 7469373..7470026 1 NC_022657.1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; putative two-component system response regulator 7470026 17447509 AFR_34195 Actinoplanes friuliensis DSM 7358 putative two-component system response regulator YP_008738150.1 7469373 D 1246995 CDS YP_008738151.1 556569726 17447510 7470050..7470868 1 NC_022657.1 hypothetical protein 7470868 17447510 AFR_34200 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738151.1 7470050 D 1246995 CDS YP_008738152.1 556569727 17447511 7470996..7471829 1 NC_022657.1 COG1266 Predicted metal-dependent membrane protease; abortive infection protein 7471829 17447511 AFR_34205 Actinoplanes friuliensis DSM 7358 abortive infection protein YP_008738152.1 7470996 D 1246995 CDS YP_008738153.1 556569728 17447512 7471829..7472974 1 NC_022657.1 COG4585 Signal transduction histidine kinase; histidine kinase dimerization and phosphoacceptor region 7472974 17447512 AFR_34210 Actinoplanes friuliensis DSM 7358 histidine kinase dimerization and phosphoacceptor region YP_008738153.1 7471829 D 1246995 CDS YP_008738154.1 556569729 17447513 7472971..7473630 1 NC_022657.1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; response regulator receiver 7473630 17447513 AFR_34215 Actinoplanes friuliensis DSM 7358 response regulator receiver YP_008738154.1 7472971 D 1246995 CDS YP_008738155.1 556569730 17447514 7473714..7474787 1 NC_022657.1 hypothetical protein 7474787 17447514 AFR_34220 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738155.1 7473714 D 1246995 CDS YP_008738156.1 556569731 17447515 complement(7474794..7475513) 1 NC_022657.1 hypothetical protein 7475513 17447515 AFR_34225 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738156.1 7474794 R 1246995 CDS YP_008738157.1 556569732 17447516 complement(7475629..7475940) 1 NC_022657.1 hypothetical protein 7475940 17447516 AFR_34230 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738157.1 7475629 R 1246995 CDS YP_008738158.1 556569733 17447517 complement(7475947..7477191) 1 NC_022657.1 hypothetical protein 7477191 17447517 AFR_34235 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738158.1 7475947 R 1246995 CDS YP_008738159.1 556569734 17447518 complement(7477253..7477588) 1 NC_022657.1 hypothetical protein 7477588 17447518 AFR_34240 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738159.1 7477253 R 1246995 CDS YP_008738160.1 556569735 17447519 complement(7477701..7478345) 1 NC_022657.1 hypothetical protein 7478345 17447519 AFR_34245 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738160.1 7477701 R 1246995 CDS YP_008738161.1 556569736 17447520 7478473..7479117 1 NC_022657.1 COG1974 SOS-response transcriptional repressors (RecA-mediated autopeptidases); LexA repressor 7479117 17447520 AFR_34250 Actinoplanes friuliensis DSM 7358 LexA repressor YP_008738161.1 7478473 D 1246995 CDS YP_008738162.1 556569737 17447521 complement(7479172..7484652) 1 NC_022657.1 COG0439 Biotin carboxylase; carbamoyl-phosphate synthase L chain ATP-binding protein 7484652 17447521 AFR_34255 Actinoplanes friuliensis DSM 7358 carbamoyl-phosphate synthase L chain ATP-binding protein YP_008738162.1 7479172 R 1246995 CDS YP_008738163.1 556569738 17447522 complement(7484831..7486234) 1 NC_022657.1 COG0215 Cysteinyl-tRNA synthetase; cysteinyl-tRNA synthetase 7486234 17447522 AFR_34260 Actinoplanes friuliensis DSM 7358 cysteinyl-tRNA synthetase YP_008738163.1 7484831 R 1246995 CDS YP_008738164.1 556569739 17447523 7486325..7486810 1 NC_022657.1 hypothetical protein 7486810 17447523 AFR_34265 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738164.1 7486325 D 1246995 CDS YP_008738165.1 556569740 17447524 complement(7486722..7488212) 1 NC_022657.1 hypothetical protein 7488212 17447524 AFR_34270 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738165.1 7486722 R 1246995 CDS YP_008738166.1 556569741 17447525 7488420..7490051 1 NC_022657.1 hypothetical protein 7490051 17447525 AFR_34275 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738166.1 7488420 D 1246995 CDS YP_008738167.1 556569742 17447526 complement(7490074..7491363) 1 NC_022657.1 COG1680 Beta-lactamase class C and other penicillin binding proteins; beta-lactamase 7491363 17447526 AFR_34280 Actinoplanes friuliensis DSM 7358 beta-lactamase YP_008738167.1 7490074 R 1246995 CDS YP_008738168.1 556569743 17447527 7491619..7492152 1 NC_022657.1 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; putative RNA polymerase ECF-subfamily sigma factor 7492152 17447527 AFR_34285 Actinoplanes friuliensis DSM 7358 putative RNA polymerase ECF-subfamily sigma factor YP_008738168.1 7491619 D 1246995 CDS YP_008738169.1 556569744 17447528 7492149..7492832 1 NC_022657.1 hypothetical protein 7492832 17447528 AFR_34290 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738169.1 7492149 D 1246995 CDS YP_008738170.1 556569745 17447529 7492961..7493683 1 NC_022657.1 hypothetical protein 7493683 17447529 AFR_34295 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738170.1 7492961 D 1246995 CDS YP_008738171.1 556569746 17447530 complement(7493752..7495074) 1 NC_022657.1 COG0515 Serine/threonine protein kinase; Serine/threonine protein kinase 7495074 17447530 AFR_34300 Actinoplanes friuliensis DSM 7358 Serine/threonine protein kinase YP_008738171.1 7493752 R 1246995 CDS YP_008738172.1 556569747 17447531 7495121..7495669 1 NC_022657.1 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; RNA polymerase sigma-E factor 7495669 17447531 AFR_34305 Actinoplanes friuliensis DSM 7358 RNA polymerase sigma-E factor YP_008738172.1 7495121 D 1246995 CDS YP_008738173.1 556569748 17447532 complement(7495771..7496160) 1 NC_022657.1 hypothetical protein 7496160 17447532 AFR_34310 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738173.1 7495771 R 1246995 CDS YP_008738174.1 556569749 17447533 7497031..7497774 1 NC_022657.1 COG4947 Uncharacterized protein conserved in bacteria; hypothetical protein 7497774 17447533 AFR_34315 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738174.1 7497031 D 1246995 CDS YP_008738175.1 556569750 17447534 7497905..7499044 1 NC_022657.1 hypothetical protein 7499044 17447534 AFR_34320 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738175.1 7497905 D 1246995 CDS YP_008738176.1 556569751 17447535 7499128..7500084 1 NC_022657.1 COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components; putative ABC transporter substrate-binding protein 7500084 17447535 AFR_34325 Actinoplanes friuliensis DSM 7358 putative ABC transporter substrate-binding protein YP_008738176.1 7499128 D 1246995 CDS YP_008738177.1 556569752 17447536 complement(7500085..7501101) 1 NC_022657.1 hypothetical protein 7501101 17447536 AFR_34330 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738177.1 7500085 R 1246995 CDS YP_008738178.1 556569753 17447537 complement(7501098..7501640) 1 NC_022657.1 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; putative RNA polymerase ECF-subfamily sigma factor 7501640 17447537 AFR_34335 Actinoplanes friuliensis DSM 7358 putative RNA polymerase ECF-subfamily sigma factor YP_008738178.1 7501098 R 1246995 CDS YP_008738179.1 556569754 17447538 7501899..7503269 1 NC_022657.1 coagulation factor 5/8 type domain-containing protein 7503269 17447538 AFR_34340 Actinoplanes friuliensis DSM 7358 coagulation factor 5/8 type domain-containing protein YP_008738179.1 7501899 D 1246995 CDS YP_008738180.1 556569755 17447539 7503328..7503963 1 NC_022657.1 COG1802 Transcriptional regulators; GntR family transcriptional regulator 7503963 17447539 AFR_34345 Actinoplanes friuliensis DSM 7358 GntR family transcriptional regulator YP_008738180.1 7503328 D 1246995 CDS YP_008738181.1 556569756 17447540 7504034..7505653 1 NC_022657.1 COG0154 Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases; allophanate hydrolase 7505653 17447540 AFR_34350 Actinoplanes friuliensis DSM 7358 allophanate hydrolase YP_008738181.1 7504034 D 1246995 CDS YP_008738182.1 556569757 17447541 7505650..7506342 1 NC_022657.1 COG1335 Amidases related to nicotinamidase; isochorismatase hydrolase 7506342 17447541 AFR_34355 Actinoplanes friuliensis DSM 7358 isochorismatase hydrolase YP_008738182.1 7505650 D 1246995 CDS YP_008738183.1 556569758 17447542 7506344..7507009 1 NC_022657.1 COG1335 Amidases related to nicotinamidase; isochorismatase-like hydrolase 7507009 17447542 AFR_34360 Actinoplanes friuliensis DSM 7358 isochorismatase-like hydrolase YP_008738183.1 7506344 D 1246995 CDS YP_008738184.1 556569759 17447543 7507006..7508601 1 NC_022657.1 COG2252 Permeases; xanthine/uracil/vitamin C permease 7508601 17447543 AFR_34365 Actinoplanes friuliensis DSM 7358 xanthine/uracil/vitamin C permease YP_008738184.1 7507006 D 1246995 CDS YP_008738185.1 556569760 17447544 7508669..7509040 1 NC_022657.1 hypothetical protein 7509040 17447544 AFR_34370 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738185.1 7508669 D 1246995 CDS YP_008738186.1 556569761 17447545 complement(7509021..7510154) 1 NC_022657.1 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases; FAD-binding monooxygenase 7510154 17447545 AFR_34375 Actinoplanes friuliensis DSM 7358 FAD-binding monooxygenase YP_008738186.1 7509021 R 1246995 CDS YP_008738187.1 556569762 17447546 7510208..7510936 1 NC_022657.1 COG1309 Transcriptional regulator; TetR family transcriptional regulator 7510936 17447546 AFR_34380 Actinoplanes friuliensis DSM 7358 TetR family transcriptional regulator YP_008738187.1 7510208 D 1246995 CDS YP_008738188.1 556569763 17447547 7510936..7511844 1 NC_022657.1 COG0524 Sugar kinases, ribokinase family; PfkB domain-containing protein 7511844 17447547 AFR_34385 Actinoplanes friuliensis DSM 7358 PfkB domain-containing protein YP_008738188.1 7510936 D 1246995 CDS YP_008738189.1 556569764 17447548 7511893..7513029 1 NC_022657.1 COG1680 Beta-lactamase class C and other penicillin binding proteins; Beta-lactamase class C-related penicillin binding protein 7513029 17447548 AFR_34390 Actinoplanes friuliensis DSM 7358 Beta-lactamase class C-related penicillin binding protein YP_008738189.1 7511893 D 1246995 CDS YP_008738190.1 556569765 17447549 7513098..7515275 1 NC_022657.1 COG4870 Cysteine protease; outer membrane autotransporter barrel domain-containing protein 7515275 17447549 AFR_34395 Actinoplanes friuliensis DSM 7358 outer membrane autotransporter barrel domain-containing protein YP_008738190.1 7513098 D 1246995 CDS YP_008738191.1 556569766 17447550 complement(7515327..7516205) 1 NC_022657.1 COG2207 AraC-type DNA-binding domain-containing proteins; AraC family transcription regulator 7516205 17447550 AFR_34400 Actinoplanes friuliensis DSM 7358 AraC family transcription regulator YP_008738191.1 7515327 R 1246995 CDS YP_008738192.1 556569767 17447551 7516294..7517283 1 NC_022657.1 COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases); oxidoreductase 7517283 17447551 AFR_34405 Actinoplanes friuliensis DSM 7358 oxidoreductase YP_008738192.1 7516294 D 1246995 CDS YP_008738193.1 556569768 17447552 7517372..7517752 1 NC_022657.1 COG0789 Predicted transcriptional regulators; putative MerR-family transcriptional regulator 7517752 17447552 AFR_34410 Actinoplanes friuliensis DSM 7358 putative MerR-family transcriptional regulator YP_008738193.1 7517372 D 1246995 CDS YP_008738194.1 556569769 17447553 7517734..7518081 1 NC_022657.1 COG0526 Thiol-disulfide isomerase and thioredoxins; putative thioredoxin 7518081 17447553 AFR_34415 Actinoplanes friuliensis DSM 7358 putative thioredoxin YP_008738194.1 7517734 D 1246995 CDS YP_008738195.1 556569770 17447554 complement(7518078..7518692) 1 NC_022657.1 hypothetical protein 7518692 17447554 AFR_34420 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738195.1 7518078 R 1246995 CDS YP_008738196.1 556569771 17447555 7518858..7519565 1 NC_022657.1 COG0288 Carbonic anhydrase; carbonic anhydrase 7519565 17447555 AFR_34425 Actinoplanes friuliensis DSM 7358 carbonic anhydrase YP_008738196.1 7518858 D 1246995 CDS YP_008738197.1 556569772 17447556 7519664..7521328 1 NC_022657.1 COG2199 FOG: GGDEF domain; diguanylate cyclase 7521328 17447556 AFR_34430 Actinoplanes friuliensis DSM 7358 diguanylate cyclase YP_008738197.1 7519664 D 1246995 CDS YP_008738198.1 556569773 17447557 7521460..7524543 1 NC_022657.1 hypothetical protein 7524543 17447557 AFR_34435 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738198.1 7521460 D 1246995 CDS YP_008738199.1 556569774 17447558 7524552..7527203 1 NC_022657.1 hypothetical protein 7527203 17447558 AFR_34440 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738199.1 7524552 D 1246995 CDS YP_008738200.1 556569775 17447559 7527203..7528138 1 NC_022657.1 COG1136 ABC-type antimicrobial peptide transport system, ATPase component; ABC transporter 7528138 17447559 AFR_34445 Actinoplanes friuliensis DSM 7358 ABC transporter YP_008738200.1 7527203 D 1246995 CDS YP_008738201.1 556569776 17447560 7528131..7528805 1 NC_022657.1 COG1136 ABC-type antimicrobial peptide transport system, ATPase component; putative ABC transporter ATP-binding protein 7528805 17447560 AFR_34450 Actinoplanes friuliensis DSM 7358 putative ABC transporter ATP-binding protein YP_008738201.1 7528131 D 1246995 CDS YP_008738202.1 556569777 17447561 7528840..7529664 1 NC_022657.1 COG0789 Predicted transcriptional regulators; regulatory protein MerR 7529664 17447561 AFR_34455 Actinoplanes friuliensis DSM 7358 regulatory protein MerR YP_008738202.1 7528840 D 1246995 CDS YP_008738203.1 556569778 17447562 complement(7529642..7530184) 1 NC_022657.1 COG1309 Transcriptional regulator; TetR family transcriptional regulator 7530184 17447562 AFR_34460 Actinoplanes friuliensis DSM 7358 TetR family transcriptional regulator YP_008738203.1 7529642 R 1246995 CDS YP_008738204.1 556569779 17447563 7530265..7531152 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); short-chain dehydrogenase/reductase SDR 7531152 17447563 AFR_34465 Actinoplanes friuliensis DSM 7358 short-chain dehydrogenase/reductase SDR YP_008738204.1 7530265 D 1246995 CDS YP_008738205.1 556569780 17447564 7531306..7532976 1 NC_022657.1 heme peroxidase 7532976 17447564 AFR_34470 Actinoplanes friuliensis DSM 7358 heme peroxidase YP_008738205.1 7531306 D 1246995 CDS YP_008738206.1 556569781 17447565 7533104..7533760 1 NC_022657.1 hypothetical protein 7533760 17447565 AFR_34475 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738206.1 7533104 D 1246995 CDS YP_008738207.1 556569782 17447566 complement(7533757..7534137) 1 NC_022657.1 hypothetical protein 7534137 17447566 AFR_34480 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738207.1 7533757 R 1246995 CDS YP_008738208.1 556569783 17447567 complement(7534514..7535605) 1 NC_022657.1 COG0457 FOG: TPR repeat; Kinesin light chain 2 7535605 17447567 AFR_34485 Actinoplanes friuliensis DSM 7358 Kinesin light chain 2 YP_008738208.1 7534514 R 1246995 CDS YP_008738209.1 556569784 17447568 complement(7535629..7535997) 1 NC_022657.1 hypothetical protein 7535997 17447568 AFR_34490 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738209.1 7535629 R 1246995 CDS YP_008738210.1 556569785 17447569 7536333..7536761 1 NC_022657.1 hypothetical protein 7536761 17447569 AFR_34495 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738210.1 7536333 D 1246995 CDS YP_008738211.1 556569786 17447570 complement(7536980..7537321) 1 NC_022657.1 hypothetical protein 7537321 17447570 AFR_34500 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738211.1 7536980 R 1246995 CDS YP_008738212.1 556569787 17447571 7537867..7538286 1 NC_022657.1 hypothetical protein 7538286 17447571 AFR_34505 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738212.1 7537867 D 1246995 CDS YP_008738213.1 556569788 17447572 7538375..7538821 1 NC_022657.1 hypothetical protein 7538821 17447572 AFR_34510 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738213.1 7538375 D 1246995 CDS YP_008738214.1 556569789 17447573 7538905..7539876 1 NC_022657.1 hypothetical protein 7539876 17447573 AFR_34515 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738214.1 7538905 D 1246995 CDS YP_008738215.1 556569790 17447574 complement(7539900..7540424) 1 NC_022657.1 hypothetical protein 7540424 17447574 AFR_34520 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738215.1 7539900 R 1246995 CDS YP_008738216.1 556569791 17447575 complement(7542808..7543572) 1 NC_022657.1 hypothetical protein 7543572 17447575 AFR_34535 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738216.1 7542808 R 1246995 CDS YP_008738217.1 556569792 17447576 complement(7543606..7544790) 1 NC_022657.1 COG1404 Subtilisin-like serine proteases; putative subtilase-family protease 7544790 17447576 AFR_34540 Actinoplanes friuliensis DSM 7358 putative subtilase-family protease YP_008738217.1 7543606 R 1246995 CDS YP_008738218.1 556569793 17447577 7544885..7545847 1 NC_022657.1 COG1378 Predicted transcriptional regulators; transcriptional regulator TrmB 7545847 17447577 AFR_34545 Actinoplanes friuliensis DSM 7358 transcriptional regulator TrmB YP_008738218.1 7544885 D 1246995 CDS YP_008738219.1 556569794 17447578 complement(7545897..7549403) 1 NC_022657.1 COG1404 Subtilisin-like serine proteases; peptidase S8/S53 subtilisin kexin sedolisin 7549403 17447578 AFR_34550 Actinoplanes friuliensis DSM 7358 peptidase S8/S53 subtilisin kexin sedolisin YP_008738219.1 7545897 R 1246995 CDS YP_008738220.1 556569795 17447579 complement(7549514..7550473) 1 NC_022657.1 COG3285 Predicted eukaryotic-type DNA primase; DNA polymerase LigD, polymerase domain-containing protein 7550473 17447579 AFR_34555 Actinoplanes friuliensis DSM 7358 DNA polymerase LigD, polymerase domain-containing protein YP_008738220.1 7549514 R 1246995 CDS YP_008738221.1 556569796 17447580 complement(7550492..7552321) 1 NC_022657.1 COG2199 FOG: GGDEF domain; putative diguanylate cyclase with PAS sensor 7552321 17447580 AFR_34560 Actinoplanes friuliensis DSM 7358 putative diguanylate cyclase with PAS sensor YP_008738221.1 7550492 R 1246995 CDS YP_008738222.1 556569797 17447581 complement(7552375..7553517) 1 NC_022657.1 major facilitator transporter 7553517 17447581 AFR_34565 Actinoplanes friuliensis DSM 7358 major facilitator transporter YP_008738222.1 7552375 R 1246995 CDS YP_008738223.1 556569798 17447582 complement(7553559..7554152) 1 NC_022657.1 COG3224 Uncharacterized protein conserved in bacteria; hypothetical protein 7554152 17447582 AFR_34570 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738223.1 7553559 R 1246995 CDS YP_008738224.1 556569799 17447583 complement(7554226..7554996) 1 NC_022657.1 COG1116 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component; sulfonate/nitrate/taurine ABC transporter ATPase 7554996 17447583 AFR_34575 Actinoplanes friuliensis DSM 7358 sulfonate/nitrate/taurine ABC transporter ATPase YP_008738224.1 7554226 R 1246995 CDS YP_008738225.1 556569800 17447584 complement(7554987..7555832) 1 NC_022657.1 COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component; sulfonate/nitrate/taurine ABC transporter permease 7555832 17447584 AFR_34580 Actinoplanes friuliensis DSM 7358 sulfonate/nitrate/taurine ABC transporter permease YP_008738225.1 7554987 R 1246995 CDS YP_008738226.1 556569801 17447585 complement(7555829..7556827) 1 NC_022657.1 COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components; sulfonate/nitrate/taurine ABC transporter periplasmic protein 7556827 17447585 AFR_34585 Actinoplanes friuliensis DSM 7358 sulfonate/nitrate/taurine ABC transporter periplasmic protein YP_008738226.1 7555829 R 1246995 CDS YP_008738227.1 556569802 17447586 complement(7556824..7557999) 1 NC_022657.1 COG0010 Arginase/agmatinase/formimionoglutamate hydrolase, arginase family; arginase/agmatinase family protein 7557999 17447586 AFR_34590 Actinoplanes friuliensis DSM 7358 arginase/agmatinase family protein YP_008738227.1 7556824 R 1246995 CDS YP_008738228.1 556569803 17447587 complement(7558212..7558721) 1 NC_022657.1 hypothetical protein 7558721 17447587 AFR_34595 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738228.1 7558212 R 1246995 CDS YP_008738229.1 556569804 17447588 7558779..7559801 1 NC_022657.1 COG4447 Uncharacterized protein related to plant photosystem II stability/assembly factor; hypothetical protein 7559801 17447588 AFR_34600 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738229.1 7558779 D 1246995 CDS YP_008738230.1 556569805 17447589 complement(7560434..7560934) 1 NC_022657.1 hypothetical protein 7560934 17447589 AFR_34605 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738230.1 7560434 R 1246995 CDS YP_008738231.1 556569806 17447590 complement(7560898..7561365) 1 NC_022657.1 hypothetical protein 7561365 17447590 AFR_34610 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738231.1 7560898 R 1246995 CDS YP_008738232.1 556569807 17447591 7561422..7562165 1 NC_022657.1 hypothetical protein 7562165 17447591 AFR_34615 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738232.1 7561422 D 1246995 CDS YP_008738233.1 556569808 17447592 complement(7562136..7562771) 1 NC_022657.1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; LuxR family transcriptional regulator 7562771 17447592 AFR_34620 Actinoplanes friuliensis DSM 7358 LuxR family transcriptional regulator YP_008738233.1 7562136 R 1246995 CDS YP_008738234.1 556569809 17447593 complement(7562723..7564009) 1 NC_022657.1 COG4564 Signal transduction histidine kinase; Sensor histidine kinase liaS 7564009 17447593 AFR_34625 Actinoplanes friuliensis DSM 7358 Sensor histidine kinase liaS YP_008738234.1 7562723 R 1246995 CDS YP_008738235.1 556569810 17447594 7564140..7565174 1 NC_022657.1 COG3239 Fatty acid desaturase; putative fatty acid desaturase 7565174 17447594 AFR_34630 Actinoplanes friuliensis DSM 7358 putative fatty acid desaturase YP_008738235.1 7564140 D 1246995 CDS YP_008738236.1 556569811 17447595 7565179..7565973 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); short-chain dehydrogenase/reductase SDR 7565973 17447595 AFR_34635 Actinoplanes friuliensis DSM 7358 short-chain dehydrogenase/reductase SDR YP_008738236.1 7565179 D 1246995 CDS YP_008738237.1 556569812 17447596 7565992..7566795 1 NC_022657.1 hypothetical protein 7566795 17447596 AFR_34640 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738237.1 7565992 D 1246995 CDS YP_008738238.1 556569813 17447597 complement(7566768..7567496) 1 NC_022657.1 COG0491 Zn-dependent hydrolases, including glyoxylases; putative metallo-beta-lactamase-like protein 7567496 17447597 AFR_34645 Actinoplanes friuliensis DSM 7358 putative metallo-beta-lactamase-like protein YP_008738238.1 7566768 R 1246995 CDS YP_008738239.1 556569814 17447598 7567649..7568752 1 NC_022657.1 COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase; phospho-N-acetylmuramoyl-pentapeptide- transferase 7568752 mraY 17447598 mraY Actinoplanes friuliensis DSM 7358 phospho-N-acetylmuramoyl-pentapeptide- transferase YP_008738239.1 7567649 D 1246995 CDS YP_008738240.1 556569815 17447600 complement(7568983..7569786) 1 NC_022657.1 COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family; inositol-phosphate phosphatase 7569786 17447600 AFR_34655 Actinoplanes friuliensis DSM 7358 inositol-phosphate phosphatase YP_008738240.1 7568983 R 1246995 CDS YP_008738241.1 556569816 17447601 7569948..7570595 1 NC_022657.1 hypothetical protein 7570595 17447601 AFR_34660 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738241.1 7569948 D 1246995 CDS YP_008738242.1 556569817 17447602 complement(7570559..7571233) 1 NC_022657.1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; two component system response regulator 7571233 17447602 AFR_34665 Actinoplanes friuliensis DSM 7358 two component system response regulator YP_008738242.1 7570559 R 1246995 CDS YP_008738243.1 556569818 17447603 complement(7571241..7572563) 1 NC_022657.1 COG4585 Signal transduction histidine kinase; two component system sensor kinase 7572563 17447603 AFR_34670 Actinoplanes friuliensis DSM 7358 two component system sensor kinase YP_008738243.1 7571241 R 1246995 CDS YP_008738244.1 556569819 17447604 complement(7573377..7574381) 1 NC_022657.1 COG2358 TRAP-type uncharacterized transport system, periplasmic component; hypothetical protein 7574381 17447604 AFR_34675 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738244.1 7573377 R 1246995 CDS YP_008738245.1 556569820 17447605 complement(7574378..7576441) 1 NC_022657.1 COG4666 TRAP-type uncharacterized transport system, fused permease components; putative DctM-like transporter 7576441 17447605 AFR_34680 Actinoplanes friuliensis DSM 7358 putative DctM-like transporter YP_008738245.1 7574378 R 1246995 CDS YP_008738246.1 556569821 17447606 7576573..7577457 1 NC_022657.1 COG0558 Phosphatidylglycerophosphate synthase; hypothetical protein 7577457 17447606 AFR_34685 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738246.1 7576573 D 1246995 CDS YP_008738247.1 556569822 17447607 7577528..7579216 1 NC_022657.1 COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases; acetyl-CoA synthetase 7579216 17447607 AFR_34690 Actinoplanes friuliensis DSM 7358 acetyl-CoA synthetase YP_008738247.1 7577528 D 1246995 CDS YP_008738248.1 556569823 17447608 complement(7579265..7580455) 1 NC_022657.1 COG3979 Uncharacterized protein contain chitin-binding domain type 3; hydrolase 7580455 17447608 AFR_34695 Actinoplanes friuliensis DSM 7358 hydrolase YP_008738248.1 7579265 R 1246995 CDS YP_008738249.1 556569824 17447609 complement(7580494..7581282) 1 NC_022657.1 COG0395 ABC-type sugar transport system, permease component; ABC transporter permease 7581282 17447609 AFR_34700 Actinoplanes friuliensis DSM 7358 ABC transporter permease YP_008738249.1 7580494 R 1246995 CDS YP_008738250.1 556569825 17447610 complement(7581375..7582283) 1 NC_022657.1 COG1175 ABC-type sugar transport systems, permease components; ABC transporter permease 7582283 17447610 AFR_34705 Actinoplanes friuliensis DSM 7358 ABC transporter permease YP_008738250.1 7581375 R 1246995 CDS YP_008738251.1 556569826 17447611 complement(7582283..7583647) 1 NC_022657.1 COG1653 ABC-type sugar transport system, periplasmic component; putative ABC transporter substrate-binding protein 7583647 17447611 AFR_34710 Actinoplanes friuliensis DSM 7358 putative ABC transporter substrate-binding protein YP_008738251.1 7582283 R 1246995 CDS YP_008738252.1 556569827 17447612 complement(7583724..7584473) 1 NC_022657.1 COG4821 Uncharacterized protein containing SIS (Sugar ISomerase) phosphosugar binding domain; hypothetical protein 7584473 17447612 AFR_34715 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738252.1 7583724 R 1246995 CDS YP_008738253.1 556569828 17447613 complement(7584470..7585387) 1 NC_022657.1 COG1737 Transcriptional regulators; putative RpiR-family transcriptional regulator 7585387 17447613 AFR_34720 Actinoplanes friuliensis DSM 7358 putative RpiR-family transcriptional regulator YP_008738253.1 7584470 R 1246995 CDS YP_008738254.1 556569829 17447614 7586549..7586965 1 NC_022657.1 N-acetyl-D-glucosamine kinase 7586965 17447614 AFR_34725 Actinoplanes friuliensis DSM 7358 N-acetyl-D-glucosamine kinase YP_008738254.1 7586549 D 1246995 CDS YP_008738255.1 556569830 17447615 7587003..7587935 1 NC_022657.1 hypothetical protein 7587935 17447615 AFR_34730 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738255.1 7587003 D 1246995 CDS YP_008738256.1 556569831 17447616 complement(7587922..7589514) 1 NC_022657.1 COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II; AMP-binding domain protein 7589514 17447616 AFR_34735 Actinoplanes friuliensis DSM 7358 AMP-binding domain protein YP_008738256.1 7587922 R 1246995 CDS YP_008738257.1 556569832 17447617 7589676..7590701 1 NC_022657.1 COG1609 Transcriptional regulators; LacI family transcriptional regulator 7590701 17447617 AFR_34740 Actinoplanes friuliensis DSM 7358 LacI family transcriptional regulator YP_008738257.1 7589676 D 1246995 CDS YP_008738258.1 556569833 17447618 7590706..7590993 1 NC_022657.1 hypothetical protein 7590993 17447618 AFR_34745 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738258.1 7590706 D 1246995 CDS YP_008738259.1 556569834 17447619 complement(7590983..7591978) 1 NC_022657.1 COG1609 Transcriptional regulators; LacI family transcriptional regulator 7591978 17447619 AFR_34750 Actinoplanes friuliensis DSM 7358 LacI family transcriptional regulator YP_008738259.1 7590983 R 1246995 CDS YP_008738260.1 556569835 17447620 7592029..7593057 1 NC_022657.1 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases; alcohol dehydrogenase GroES domain-containing protein 7593057 17447620 AFR_34755 Actinoplanes friuliensis DSM 7358 alcohol dehydrogenase GroES domain-containing protein YP_008738260.1 7592029 D 1246995 CDS YP_008738261.1 556569836 17447621 7593088..7593843 1 NC_022657.1 hypothetical protein 7593843 17447621 AFR_34760 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738261.1 7593088 D 1246995 CDS YP_008738262.1 556569837 17447622 7593893..7595548 1 NC_022657.1 COG2303 Choline dehydrogenase and related flavoproteins; putative cholesterol oxidase 7595548 17447622 AFR_34765 Actinoplanes friuliensis DSM 7358 putative cholesterol oxidase YP_008738262.1 7593893 D 1246995 CDS YP_008738263.1 556569838 17447623 complement(7595643..7596782) 1 NC_022657.1 Endoglucanase E-4 7596782 17447623 AFR_34770 Actinoplanes friuliensis DSM 7358 Endoglucanase E-4 YP_008738263.1 7595643 R 1246995 CDS YP_008738264.1 556569839 17447624 7597088..7597438 1 NC_022657.1 Protein lsr2 7597438 17447624 AFR_34775 Actinoplanes friuliensis DSM 7358 Protein lsr2 YP_008738264.1 7597088 D 1246995 CDS YP_008738265.1 556569840 17447625 7597512..7598237 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); short-chain dehydrogenase/reductase SDR 7598237 17447625 AFR_34780 Actinoplanes friuliensis DSM 7358 short-chain dehydrogenase/reductase SDR YP_008738265.1 7597512 D 1246995 CDS YP_008738266.1 556569841 17447626 7598305..7599558 1 NC_022657.1 COG5659 FOG: Transposase; putative transposase 7599558 17447626 AFR_34785 Actinoplanes friuliensis DSM 7358 putative transposase YP_008738266.1 7598305 D 1246995 CDS YP_008738267.1 556569842 17447627 complement(7599849..7601915) 1 NC_022657.1 COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs; putative oxidoreductase 7601915 17447627 AFR_34790 Actinoplanes friuliensis DSM 7358 putative oxidoreductase YP_008738267.1 7599849 R 1246995 CDS YP_008738268.1 556569843 17447628 complement(7601912..7602895) 1 NC_022657.1 COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs; putative oxidoreductase molybdopterin-binding subunit 7602895 17447628 AFR_34795 Actinoplanes friuliensis DSM 7358 putative oxidoreductase molybdopterin-binding subunit YP_008738268.1 7601912 R 1246995 CDS YP_008738269.1 556569844 17447629 complement(7602892..7603377) 1 NC_022657.1 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs; putative oxidoreductase iron-sulfur-binding subunit 7603377 17447629 AFR_34800 Actinoplanes friuliensis DSM 7358 putative oxidoreductase iron-sulfur-binding subunit YP_008738269.1 7602892 R 1246995 CDS YP_008738270.1 556569845 17447630 7603443..7604513 1 NC_022657.1 COG0451 Nucleoside-diphosphate-sugar epimerases; putative NAD-dependent epimerase/dehydratase 7604513 17447630 AFR_34805 Actinoplanes friuliensis DSM 7358 putative NAD-dependent epimerase/dehydratase YP_008738270.1 7603443 D 1246995 CDS YP_008738271.1 556569846 17447631 complement(7604542..7604775) 1 NC_022657.1 hypothetical protein 7604775 17447631 AFR_34810 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738271.1 7604542 R 1246995 CDS YP_008738272.1 556569847 17447632 complement(7604949..7608026) 1 NC_022657.1 COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain; putative diguanylate cyclase/phosphodiesterase with PAS sensor 7608026 17447632 AFR_34815 Actinoplanes friuliensis DSM 7358 putative diguanylate cyclase/phosphodiesterase with PAS sensor YP_008738272.1 7604949 R 1246995 CDS YP_008738273.1 556569848 17447633 7608107..7608748 1 NC_022657.1 COG3897 Predicted methyltransferase; putative methyltransferase 7608748 17447633 AFR_34820 Actinoplanes friuliensis DSM 7358 putative methyltransferase YP_008738273.1 7608107 D 1246995 CDS YP_008738274.1 556569849 17447634 7608841..7610064 1 NC_022657.1 COG1914 Mn2+ and Fe2+ transporters of the NRAMP family; hypothetical protein 7610064 17447634 AFR_34825 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738274.1 7608841 D 1246995 CDS YP_008738275.1 556569850 17447635 7610103..7610864 1 NC_022657.1 COG1540 Uncharacterized proteins, homologs of lactam utilization protein B; LamB/YcsF family protein 7610864 17447635 AFR_34830 Actinoplanes friuliensis DSM 7358 LamB/YcsF family protein YP_008738275.1 7610103 D 1246995 CDS YP_008738276.1 556569851 17447636 7610987..7611679 1 NC_022657.1 COG4336 Uncharacterized conserved protein; hypothetical protein 7611679 17447636 AFR_34835 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738276.1 7610987 D 1246995 CDS YP_008738277.1 556569852 17447637 7611676..7612293 1 NC_022657.1 COG2049 Allophanate hydrolase subunit 1; allophanate hydrolase 7612293 17447637 AFR_34840 Actinoplanes friuliensis DSM 7358 allophanate hydrolase YP_008738277.1 7611676 D 1246995 CDS YP_008738278.1 556569853 17447638 7612290..7613486 1 NC_022657.1 COG1984 Allophanate hydrolase subunit 2; urea amidolyase 7613486 17447638 AFR_34845 Actinoplanes friuliensis DSM 7358 urea amidolyase YP_008738278.1 7612290 D 1246995 CDS YP_008738279.1 556569854 17447639 7613520..7614161 1 NC_022657.1 COG1802 Transcriptional regulators; GntR family transcriptional regulator 7614161 17447639 AFR_34850 Actinoplanes friuliensis DSM 7358 GntR family transcriptional regulator YP_008738279.1 7613520 D 1246995 CDS YP_008738280.1 556569855 17447640 complement(7614171..7614899) 1 NC_022657.1 COG1011 Predicted hydrolase (HAD superfamily); putative haloacid dehalogenase-like hydrolase 7614899 17447640 AFR_34855 Actinoplanes friuliensis DSM 7358 putative haloacid dehalogenase-like hydrolase YP_008738280.1 7614171 R 1246995 CDS YP_008738281.1 556569856 17447641 complement(7614909..7615670) 1 NC_022657.1 COG1940 Transcriptional regulator/sugar kinase; polyphosphate glucokinase 7615670 17447641 AFR_34860 Actinoplanes friuliensis DSM 7358 polyphosphate glucokinase YP_008738281.1 7614909 R 1246995 CDS YP_008738282.1 556569857 17447642 complement(7615706..7616617) 1 NC_022657.1 COG0122 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase; hypothetical protein 7616617 17447642 AFR_34865 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738282.1 7615706 R 1246995 CDS YP_008738283.1 556569858 17447643 complement(7616952..7618193) 1 NC_022657.1 hypothetical protein 7618193 17447643 AFR_34870 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738283.1 7616952 R 1246995 CDS YP_008738284.1 556569859 17447644 complement(7618297..7619085) 1 NC_022657.1 hypothetical protein 7619085 17447644 AFR_34875 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738284.1 7618297 R 1246995 CDS YP_008738285.1 556569860 17447645 complement(7619282..7619977) 1 NC_022657.1 COG4315 Uncharacterized protein conserved in bacteria; hypothetical protein 7619977 17447645 AFR_34880 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738285.1 7619282 R 1246995 CDS YP_008738286.1 556569861 17447646 complement(7620258..7621046) 1 NC_022657.1 hypothetical protein 7621046 17447646 AFR_34885 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738286.1 7620258 R 1246995 CDS YP_008738287.1 556569862 17447647 complement(7621043..7621531) 1 NC_022657.1 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; RNA polymerase sigma factor SigL 7621531 17447647 AFR_34890 Actinoplanes friuliensis DSM 7358 RNA polymerase sigma factor SigL YP_008738287.1 7621043 R 1246995 CDS YP_008738288.1 556569863 17447648 complement(7622225..7622572) 1 NC_022657.1 COG3631 Ketosteroid isomerase-related protein; hypothetical protein 7622572 17447648 AFR_34895 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738288.1 7622225 R 1246995 CDS YP_008738289.1 556569864 17447649 complement(7622569..7623009) 1 NC_022657.1 COG3832 Uncharacterized conserved protein; activator of hsp90 ATPase 1 family protein 7623009 17447649 AFR_34900 Actinoplanes friuliensis DSM 7358 activator of hsp90 ATPase 1 family protein YP_008738289.1 7622569 R 1246995 CDS YP_008738290.1 556569865 17447650 complement(7623006..7623233) 1 NC_022657.1 COG0640 Predicted transcriptional regulators; regulatory protein ArsR 7623233 17447650 AFR_34905 Actinoplanes friuliensis DSM 7358 regulatory protein ArsR YP_008738290.1 7623006 R 1246995 CDS YP_008738291.1 556569866 17447651 complement(7623551..7624516) 1 NC_022657.1 COG2380 Uncharacterized protein conserved in bacteria; hypothetical protein 7624516 17447651 AFR_34910 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738291.1 7623551 R 1246995 CDS YP_008738292.1 556569867 17447652 complement(7624522..7626990) 1 NC_022657.1 COG0419 ATPase involved in DNA repair; putative ATP-dependent dsDNA exonuclease C subunit 7626990 17447652 AFR_34915 Actinoplanes friuliensis DSM 7358 putative ATP-dependent dsDNA exonuclease C subunit YP_008738292.1 7624522 R 1246995 CDS YP_008738293.1 556569868 17447653 complement(7627008..7628159) 1 NC_022657.1 COG0420 DNA repair exonuclease; nuclease SbcCD subunit D 7628159 17447653 AFR_34920 Actinoplanes friuliensis DSM 7358 nuclease SbcCD subunit D YP_008738293.1 7627008 R 1246995 CDS YP_008738294.1 556569869 17447654 complement(7628169..7629899) 1 NC_022657.1 COG0433 Predicted ATPase; hypothetical protein 7629899 17447654 AFR_34925 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738294.1 7628169 R 1246995 CDS YP_008738295.1 556569870 17447655 complement(7630025..7630810) 1 NC_022657.1 COG1985 Pyrimidine reductase, riboflavin biosynthesis; hypothetical protein 7630810 17447655 AFR_34930 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738295.1 7630025 R 1246995 CDS YP_008738296.1 556569871 17447656 7630936..7631952 1 NC_022657.1 COG1609 Transcriptional regulators; LacI family transcriptional regulator 7631952 17447656 AFR_34935 Actinoplanes friuliensis DSM 7358 LacI family transcriptional regulator YP_008738296.1 7630936 D 1246995 CDS YP_008738297.1 556569872 17447657 7632098..7632859 1 NC_022657.1 COG0281 Malic enzyme; hypothetical protein 7632859 17447657 AFR_34940 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738297.1 7632098 D 1246995 CDS YP_008738298.1 556569873 17447658 7632953..7634023 1 NC_022657.1 hypothetical protein 7634023 17447658 AFR_34945 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738298.1 7632953 D 1246995 CDS YP_008738299.1 556569874 17447659 complement(7634077..7634265) 1 NC_022657.1 hypothetical protein 7634265 17447659 AFR_34950 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738299.1 7634077 R 1246995 CDS YP_008738300.1 556569875 17447660 complement(7634262..7635257) 1 NC_022657.1 COG0502 Biotin synthase and related enzymes; biotin synthase 7635257 17447660 AFR_34955 Actinoplanes friuliensis DSM 7358 biotin synthase YP_008738300.1 7634262 R 1246995 CDS YP_008738301.1 556569876 17447661 7635354..7636490 1 NC_022657.1 COG0156 7-keto-8-aminopelargonate synthetase and related enzymes; 8-amino-7-oxononanoate synthase 7636490 17447661 AFR_34960 Actinoplanes friuliensis DSM 7358 8-amino-7-oxononanoate synthase YP_008738301.1 7635354 D 1246995 CDS YP_008738302.1 556569877 17447662 7636478..7637335 1 NC_022657.1 COG0132 Dethiobiotin synthetase; dethiobiotin synthase 7637335 17447662 AFR_34965 Actinoplanes friuliensis DSM 7358 dethiobiotin synthase YP_008738302.1 7636478 D 1246995 CDS YP_008738303.1 556569878 17447663 7637335..7637802 1 NC_022657.1 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; GCN5-like N-acetyltransferase 7637802 17447663 AFR_34970 Actinoplanes friuliensis DSM 7358 GCN5-like N-acetyltransferase YP_008738303.1 7637335 D 1246995 CDS YP_008738304.1 556569879 17447664 7637919..7639184 1 NC_022657.1 COG1253 Hemolysins and related proteins containing CBS domains; hypothetical protein 7639184 17447664 AFR_34975 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738304.1 7637919 D 1246995 CDS YP_008738305.1 556569880 17447665 complement(7639181..7641487) 1 NC_022657.1 COG1554 Trehalose and maltose hydrolases (possible phosphorylases); Kojibiose phosphorylase 7641487 17447665 AFR_34980 Actinoplanes friuliensis DSM 7358 Kojibiose phosphorylase YP_008738305.1 7639181 R 1246995 CDS YP_008738306.1 556569881 17447666 complement(7641480..7642370) 1 NC_022657.1 COG0524 Sugar kinases, ribokinase family; putative PfkB-family carbohydrate kinase 7642370 17447666 AFR_34985 Actinoplanes friuliensis DSM 7358 putative PfkB-family carbohydrate kinase YP_008738306.1 7641480 R 1246995 CDS YP_008738307.1 556569882 17447667 7642509..7643087 1 NC_022657.1 COG2203 FOG: GAF domain; hypothetical protein 7643087 17447667 AFR_34990 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738307.1 7642509 D 1246995 CDS YP_008738308.1 556569883 17447668 7643136..7644044 1 NC_022657.1 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase; hypothetical protein 7644044 17447668 AFR_34995 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738308.1 7643136 D 1246995 CDS YP_008738309.1 556569884 17447669 7644228..7644422 1 NC_022657.1 hypothetical protein 7644422 17447669 AFR_35000 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738309.1 7644228 D 1246995 CDS YP_008738310.1 556569885 17447670 7644533..7645399 1 NC_022657.1 hypothetical protein 7645399 17447670 AFR_35005 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738310.1 7644533 D 1246995 CDS YP_008738311.1 556569886 17447671 7645409..7645783 1 NC_022657.1 COG2176 DNA polymerase III, alpha subunit (gram-positive type); hypothetical protein 7645783 17447671 AFR_35010 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738311.1 7645409 D 1246995 CDS YP_008738312.1 556569887 17447672 complement(7646941..7648071) 1 NC_022657.1 COG2220 Predicted Zn-dependent hydrolases of the beta-lactamase fold; N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D 7648071 17447672 AFR_35015 Actinoplanes friuliensis DSM 7358 N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D YP_008738312.1 7646941 R 1246995 CDS YP_008738313.1 556569888 17447673 7648191..7648769 1 NC_022657.1 hypothetical protein 7648769 17447673 AFR_35020 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738313.1 7648191 D 1246995 CDS YP_008738314.1 556569889 17447674 7648793..7650289 1 NC_022657.1 COG0232 dGTP triphosphohydrolase; putative deoxyguanosinetriphosphate triphosphohydrolase 7650289 17447674 AFR_35025 Actinoplanes friuliensis DSM 7358 putative deoxyguanosinetriphosphate triphosphohydrolase YP_008738314.1 7648793 D 1246995 CDS YP_008738315.1 556569890 17447675 7650342..7650893 1 NC_022657.1 hypothetical protein 7650893 17447675 AFR_35030 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738315.1 7650342 D 1246995 CDS YP_008738316.1 556569891 17447676 7650921..7651685 1 NC_022657.1 hypothetical protein 7651685 17447676 AFR_35035 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738316.1 7650921 D 1246995 CDS YP_008738317.1 556569892 17447677 7651682..7652059 1 NC_022657.1 hypothetical protein 7652059 17447677 AFR_35040 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738317.1 7651682 D 1246995 CDS YP_008738318.1 556569893 17447678 complement(7652048..7652407) 1 NC_022657.1 hypothetical protein 7652407 17447678 AFR_35045 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738318.1 7652048 R 1246995 CDS YP_008738319.1 556569894 17447679 complement(7652656..7653591) 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); putative short-chain dehydrogenase 7653591 17447679 AFR_35050 Actinoplanes friuliensis DSM 7358 putative short-chain dehydrogenase YP_008738319.1 7652656 R 1246995 CDS YP_008738320.1 556569895 17447680 7653702..7654769 1 NC_022657.1 COG1793 ATP-dependent DNA ligase; ATP-dependent DNA ligase 7654769 ligC 17447680 ligC Actinoplanes friuliensis DSM 7358 ATP-dependent DNA ligase YP_008738320.1 7653702 D 1246995 CDS YP_008738321.1 556569896 17447681 7654836..7656407 1 NC_022657.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); putative protease 7656407 17447681 AFR_35060 Actinoplanes friuliensis DSM 7358 putative protease YP_008738321.1 7654836 D 1246995 CDS YP_008738322.1 556569897 17447682 complement(7656358..7656840) 1 NC_022657.1 COG1226 Kef-type K+ transport systems, predicted NAD-binding component; putative ion transport integral membrane protein 7656840 17447682 AFR_35065 Actinoplanes friuliensis DSM 7358 putative ion transport integral membrane protein YP_008738322.1 7656358 R 1246995 CDS YP_008738323.1 556569898 17447683 7656879..7657355 1 NC_022657.1 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; putative GCN5-related N-acetyltransferase 7657355 17447683 AFR_35070 Actinoplanes friuliensis DSM 7358 putative GCN5-related N-acetyltransferase YP_008738323.1 7656879 D 1246995 CDS YP_008738324.1 556569899 17447684 complement(7657359..7659590) 1 NC_022657.1 hypothetical protein 7659590 17447684 AFR_35075 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738324.1 7657359 R 1246995 CDS YP_008738325.1 556569900 17447685 complement(7659587..7660261) 1 NC_022657.1 COG1136 ABC-type antimicrobial peptide transport system, ATPase component; ABC transporter-like protein 7660261 17447685 AFR_35080 Actinoplanes friuliensis DSM 7358 ABC transporter-like protein YP_008738325.1 7659587 R 1246995 CDS YP_008738326.1 556569901 17447686 7660456..7661697 1 NC_022657.1 COG4585 Signal transduction histidine kinase; histidine kinase dimerization and phosphoacceptor region 7661697 17447686 AFR_35085 Actinoplanes friuliensis DSM 7358 histidine kinase dimerization and phosphoacceptor region YP_008738326.1 7660456 D 1246995 CDS YP_008738327.1 556569902 17447687 7661694..7662362 1 NC_022657.1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; two component LuxR family transcriptional regulator 7662362 17447687 AFR_35090 Actinoplanes friuliensis DSM 7358 two component LuxR family transcriptional regulator YP_008738327.1 7661694 D 1246995 CDS YP_008738328.1 556569903 17447688 complement(7662320..7663312) 1 NC_022657.1 COG0583 Transcriptional regulator; LysR-family transcriptional regulator 7663312 17447688 AFR_35095 Actinoplanes friuliensis DSM 7358 LysR-family transcriptional regulator YP_008738328.1 7662320 R 1246995 CDS YP_008738329.1 556569904 17447689 7663350..7664348 1 NC_022657.1 COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases; dehydrogenase 7664348 17447689 AFR_35100 Actinoplanes friuliensis DSM 7358 dehydrogenase YP_008738329.1 7663350 D 1246995 CDS YP_008738330.1 556569905 17447690 7664345..7664752 1 NC_022657.1 hypothetical protein 7664752 17447690 AFR_35105 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738330.1 7664345 D 1246995 CDS YP_008738331.1 556569906 17447691 complement(7664882..7665910) 1 NC_022657.1 COG3285 Predicted eukaryotic-type DNA primase; hypothetical protein 7665910 17447691 AFR_35110 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738331.1 7664882 R 1246995 CDS YP_008738332.1 556569907 17447692 complement(7665988..7666485) 1 NC_022657.1 hypothetical protein 7666485 17447692 AFR_35115 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738332.1 7665988 R 1246995 CDS YP_008738333.1 556569908 17447693 complement(7666603..7667076) 1 NC_022657.1 hypothetical protein 7667076 17447693 AFR_35120 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738333.1 7666603 R 1246995 CDS YP_008738334.1 556569909 17447694 7667144..7667548 1 NC_022657.1 COG0229 Conserved domain frequently associated with peptide methionine sulfoxide reductase; putative methionine sulfoxide reductase 7667548 17447694 AFR_35125 Actinoplanes friuliensis DSM 7358 putative methionine sulfoxide reductase YP_008738334.1 7667144 D 1246995 CDS YP_008738335.1 556569910 17447695 complement(7667529..7668011) 1 NC_022657.1 COG0262 Dihydrofolate reductase; putative dihydrofolate reductase 7668011 17447695 AFR_35130 Actinoplanes friuliensis DSM 7358 putative dihydrofolate reductase YP_008738335.1 7667529 R 1246995 CDS YP_008738336.1 556569911 17447696 complement(7668008..7668805) 1 NC_022657.1 COG0207 Thymidylate synthase; thymidylate synthase 7668805 17447696 AFR_35135 Actinoplanes friuliensis DSM 7358 thymidylate synthase YP_008738336.1 7668008 R 1246995 CDS YP_008738337.1 556569912 17447697 complement(7668870..7669124) 1 NC_022657.1 hypothetical protein 7669124 17447697 AFR_35140 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738337.1 7668870 R 1246995 CDS YP_008738338.1 556569913 17447698 complement(7669199..7669414) 1 NC_022657.1 hypothetical protein 7669414 17447698 AFR_35145 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738338.1 7669199 R 1246995 CDS YP_008738339.1 556569914 17447699 complement(7669465..7670070) 1 NC_022657.1 COG0655 Multimeric flavodoxin WrbA; hypothetical protein 7670070 17447699 AFR_35150 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738339.1 7669465 R 1246995 CDS YP_008738340.1 556569915 17447700 complement(7670145..7670420) 1 NC_022657.1 COG0296 1,4-alpha-glucan branching enzyme; hypothetical protein 7670420 17447700 AFR_35155 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738340.1 7670145 R 1246995 CDS YP_008738341.1 556569916 17447701 7670497..7670928 1 NC_022657.1 COG2153 Predicted acyltransferase; putative GCN5-related N-acetyltransferase 7670928 17447701 AFR_35160 Actinoplanes friuliensis DSM 7358 putative GCN5-related N-acetyltransferase YP_008738341.1 7670497 D 1246995 CDS YP_008738342.1 556569917 17447702 complement(7670925..7671632) 1 NC_022657.1 COG3253 Uncharacterized conserved protein; putative chlorite dismutase 7671632 17447702 AFR_35165 Actinoplanes friuliensis DSM 7358 putative chlorite dismutase YP_008738342.1 7670925 R 1246995 CDS YP_008738343.1 556569918 17447703 complement(7671629..7673023) 1 NC_022657.1 COG1232 Protoporphyrinogen oxidase; putative protoporphyrinogen oxidase 7673023 17447703 AFR_35170 Actinoplanes friuliensis DSM 7358 putative protoporphyrinogen oxidase YP_008738343.1 7671629 R 1246995 CDS YP_008738344.1 556569919 17447704 complement(7673090..7674094) 1 NC_022657.1 COG0407 Uroporphyrinogen-III decarboxylase; uroporphyrinogen decarboxylase 7674094 17447704 AFR_35175 Actinoplanes friuliensis DSM 7358 uroporphyrinogen decarboxylase YP_008738344.1 7673090 R 1246995 CDS YP_008738345.1 556569920 17447705 7674205..7674777 1 NC_022657.1 hypothetical protein 7674777 17447705 AFR_35180 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738345.1 7674205 D 1246995 CDS YP_008738346.1 556569921 17447706 complement(7674774..7675772) 1 NC_022657.1 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain; putative serine protease 7675772 17447706 AFR_35185 Actinoplanes friuliensis DSM 7358 putative serine protease YP_008738346.1 7674774 R 1246995 CDS YP_008738347.1 556569922 17447707 7676098..7677291 1 NC_022657.1 COG0349 Ribonuclease D; ribonuclease D 7677291 17447707 AFR_35190 Actinoplanes friuliensis DSM 7358 ribonuclease D YP_008738347.1 7676098 D 1246995 CDS YP_008738348.1 556569923 17447708 7677288..7678235 1 NC_022657.1 COG4034 Uncharacterized protein conserved in archaea; hypothetical protein 7678235 17447708 AFR_35195 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738348.1 7677288 D 1246995 CDS YP_008738349.1 556569924 17447709 7678433..7679629 1 NC_022657.1 COG0183 Acetyl-CoA acetyltransferase; acetyl-CoA acetyltransferase 7679629 17447709 AFR_35200 Actinoplanes friuliensis DSM 7358 acetyl-CoA acetyltransferase YP_008738349.1 7678433 D 1246995 CDS YP_008738350.1 556569925 17447710 7679626..7681695 1 NC_022657.1 COG1024 Enoyl-CoA hydratase/carnithine racemase; putative 3-hydroxyacyl-CoA dehydrogenase 7681695 17447710 AFR_35205 Actinoplanes friuliensis DSM 7358 putative 3-hydroxyacyl-CoA dehydrogenase YP_008738350.1 7679626 D 1246995 CDS YP_008738351.1 556569926 17447711 7681845..7682663 1 NC_022657.1 hypothetical protein 7682663 17447711 AFR_35210 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738351.1 7681845 D 1246995 CDS YP_008738352.1 556569927 17447712 7682783..7683883 1 NC_022657.1 hypothetical protein 7683883 17447712 AFR_35215 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738352.1 7682783 D 1246995 CDS YP_008738353.1 556569928 17447713 7684051..7685244 1 NC_022657.1 hypothetical protein 7685244 17447713 AFR_35220 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738353.1 7684051 D 1246995 CDS YP_008738354.1 556569929 17447714 complement(7685663..7686892) 1 NC_022657.1 COG0642 Signal transduction histidine kinase; putative two-component system sensor kinase 7686892 17447714 AFR_35225 Actinoplanes friuliensis DSM 7358 putative two-component system sensor kinase YP_008738354.1 7685663 R 1246995 CDS YP_008738355.1 556569930 17447715 complement(7686889..7687581) 1 NC_022657.1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; putative two-component system response regulator 7687581 17447715 AFR_35230 Actinoplanes friuliensis DSM 7358 putative two-component system response regulator YP_008738355.1 7686889 R 1246995 CDS YP_008738356.1 556569931 17447716 complement(7687669..7689045) 1 NC_022657.1 hypothetical protein 7689045 17447716 AFR_35235 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738356.1 7687669 R 1246995 CDS YP_008738357.1 556569932 17447717 complement(7689027..7690358) 1 NC_022657.1 hypothetical protein 7690358 17447717 AFR_35240 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738357.1 7689027 R 1246995 CDS YP_008738358.1 556569933 17447718 complement(7690355..7691674) 1 NC_022657.1 hypothetical protein 7691674 17447718 AFR_35245 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738358.1 7690355 R 1246995 CDS YP_008738359.1 556569934 17447719 complement(7691718..7693643) 1 NC_022657.1 COG1154 Deoxyxylulose-5-phosphate synthase; 1-deoxy-D-xylulose-5-phosphate synthase 7693643 17447719 AFR_35250 Actinoplanes friuliensis DSM 7358 1-deoxy-D-xylulose-5-phosphate synthase YP_008738359.1 7691718 R 1246995 CDS YP_008738360.1 556569935 17447720 7693770..7695122 1 NC_022657.1 COG1301 Na+/H+-dicarboxylate symporters; C4-dicarboxylate transport protein 7695122 17447720 AFR_35255 Actinoplanes friuliensis DSM 7358 C4-dicarboxylate transport protein YP_008738360.1 7693770 D 1246995 CDS YP_008738361.1 556569936 17447721 complement(7695102..7696379) 1 NC_022657.1 COG2265 SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase; hypothetical protein 7696379 17447721 AFR_35260 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738361.1 7695102 R 1246995 CDS YP_008738362.1 556569937 17447722 complement(7696376..7698478) 1 NC_022657.1 COG0531 Amino acid transporters; hypothetical protein 7698478 17447722 AFR_35265 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738362.1 7696376 R 1246995 CDS YP_008738363.1 556569938 17447723 7698547..7699206 1 NC_022657.1 COG0569 K+ transport systems, NAD-binding component; Trk system potassium uptake protein trkA 7699206 17447723 AFR_35270 Actinoplanes friuliensis DSM 7358 Trk system potassium uptake protein trkA YP_008738363.1 7698547 D 1246995 CDS YP_008738364.1 556569939 17447724 7699209..7699883 1 NC_022657.1 COG0569 K+ transport systems, NAD-binding component; TrkA-like trk system potassium uptake protein 7699883 17447724 AFR_35275 Actinoplanes friuliensis DSM 7358 TrkA-like trk system potassium uptake protein YP_008738364.1 7699209 D 1246995 CDS YP_008738365.1 556569940 17447725 complement(7699880..7700689) 1 NC_022657.1 hypothetical protein 7700689 17447725 AFR_35280 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738365.1 7699880 R 1246995 CDS YP_008738366.1 556569941 17447726 complement(7700686..7701063) 1 NC_022657.1 hypothetical protein 7701063 17447726 AFR_35285 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738366.1 7700686 R 1246995 CDS YP_008738367.1 556569942 17447727 complement(7701206..7701916) 1 NC_022657.1 hypothetical protein 7701916 17447727 AFR_35290 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738367.1 7701206 R 1246995 CDS YP_008738368.1 556569943 17447728 complement(7701939..7702451) 1 NC_022657.1 COG0756 dUTPase; deoxyuridine 5'-triphosphate nucleotidohydrolase 7702451 dut 17447728 dut Actinoplanes friuliensis DSM 7358 deoxyuridine 5'-triphosphate nucleotidohydrolase YP_008738368.1 7701939 R 1246995 CDS YP_008738369.1 556569944 17447729 7702507..7702989 1 NC_022657.1 hypothetical protein 7702989 17447729 AFR_35300 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738369.1 7702507 D 1246995 CDS YP_008738370.1 556569945 17447730 complement(7702979..7703818) 1 NC_022657.1 hypothetical protein 7703818 17447730 AFR_35305 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738370.1 7702979 R 1246995 CDS YP_008738371.1 556569946 17447731 complement(7703978..7704274) 1 NC_022657.1 hypothetical protein 7704274 17447731 AFR_35310 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738371.1 7703978 R 1246995 CDS YP_008738372.1 556569947 17447732 7704661..7705197 1 NC_022657.1 hypothetical protein 7705197 17447732 AFR_35315 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738372.1 7704661 D 1246995 CDS YP_008738373.1 556569948 17447733 complement(7705203..7706030) 1 NC_022657.1 COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family; putative myo-inositol 1-monophosphatase 7706030 17447733 AFR_35320 Actinoplanes friuliensis DSM 7358 putative myo-inositol 1-monophosphatase YP_008738373.1 7705203 R 1246995 CDS YP_008738374.1 556569949 17447734 7706288..7707859 1 NC_022657.1 COG0568 DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32); RNA polymerase sigma factor 7707859 17447734 AFR_35325 Actinoplanes friuliensis DSM 7358 RNA polymerase sigma factor YP_008738374.1 7706288 D 1246995 CDS YP_008738375.1 556569950 17447735 7708118..7708390 1 NC_022657.1 hypothetical protein 7708390 17447735 AFR_35330 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738375.1 7708118 D 1246995 CDS YP_008738376.1 556569951 17447736 complement(7709851..7711572) 1 NC_022657.1 COG1061 DNA or RNA helicases of superfamily II; hypothetical protein 7711572 17447736 AFR_35335 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738376.1 7709851 R 1246995 CDS YP_008738377.1 556569952 17447737 complement(7711684..7712298) 1 NC_022657.1 COG2860 Predicted membrane protein; hypothetical protein 7712298 17447737 AFR_35340 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738377.1 7711684 R 1246995 CDS YP_008738378.1 556569953 17447738 complement(7712315..7712533) 1 NC_022657.1 hypothetical protein 7712533 17447738 AFR_35345 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738378.1 7712315 R 1246995 CDS YP_008738379.1 556569954 17447739 7712702..7713649 1 NC_022657.1 COG2313 Uncharacterized enzyme involved in pigment biosynthesis; indigoidine synthase A family protein 7713649 17447739 AFR_35350 Actinoplanes friuliensis DSM 7358 indigoidine synthase A family protein YP_008738379.1 7712702 D 1246995 CDS YP_008738380.1 556569955 17447740 7713646..7714629 1 NC_022657.1 COG0524 Sugar kinases, ribokinase family; putative PfkB-family carbohydrate kinase 7714629 17447740 AFR_35355 Actinoplanes friuliensis DSM 7358 putative PfkB-family carbohydrate kinase YP_008738380.1 7713646 D 1246995 CDS YP_008738381.1 556569956 17447741 complement(7714626..7714967) 1 NC_022657.1 hypothetical protein 7714967 17447741 AFR_35360 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738381.1 7714626 R 1246995 CDS YP_008738382.1 556569957 17447742 7715075..7717459 1 NC_022657.1 COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain; hypothetical protein 7717459 17447742 AFR_35365 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738382.1 7715075 D 1246995 CDS YP_008738383.1 556569958 17447743 complement(7717425..7717991) 1 NC_022657.1 COG0177 Predicted EndoIII-related endonuclease; hypothetical protein 7717991 17447743 AFR_35370 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738383.1 7717425 R 1246995 CDS YP_008738384.1 556569959 17447744 7718065..7718790 1 NC_022657.1 COG2188 Transcriptional regulators; GntR family transcriptional regulator 7718790 17447744 AFR_35375 Actinoplanes friuliensis DSM 7358 GntR family transcriptional regulator YP_008738384.1 7718065 D 1246995 CDS YP_008738385.1 556569960 17447745 7718790..7719506 1 NC_022657.1 COG0274 Deoxyribose-phosphate aldolase; deoxyribose-phosphate aldolase 7719506 17447745 AFR_35380 Actinoplanes friuliensis DSM 7358 deoxyribose-phosphate aldolase YP_008738385.1 7718790 D 1246995 CDS YP_008738386.1 556569961 17447746 complement(7719500..7722664) 1 NC_022657.1 hypothetical protein 7722664 17447746 AFR_35385 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738386.1 7719500 R 1246995 CDS YP_008738387.1 556569962 17447747 7722761..7725142 1 NC_022657.1 COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain; PAS/PAC and GAF sensor-containing diguanylate cyclase/phosphodiesterase 7725142 17447747 AFR_35390 Actinoplanes friuliensis DSM 7358 PAS/PAC and GAF sensor-containing diguanylate cyclase/phosphodiesterase YP_008738387.1 7722761 D 1246995 CDS YP_008738388.1 556569963 17447748 7725139..7725423 1 NC_022657.1 hypothetical protein 7725423 17447748 AFR_35395 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738388.1 7725139 D 1246995 CDS YP_008738389.1 556569964 17447749 7725440..7726027 1 NC_022657.1 COG0515 Serine/threonine protein kinase; putative aminoglycoside phosphotransferase 7726027 17447749 AFR_35400 Actinoplanes friuliensis DSM 7358 putative aminoglycoside phosphotransferase YP_008738389.1 7725440 D 1246995 CDS YP_008738390.1 556569965 17447750 7726015..7726437 1 NC_022657.1 COG1490 D-Tyr-tRNAtyr deacylase; D-tyrosyl-tRNA(Tyr) deacylase 7726437 17447750 AFR_35405 Actinoplanes friuliensis DSM 7358 D-tyrosyl-tRNA(Tyr) deacylase YP_008738390.1 7726015 D 1246995 CDS YP_008738391.1 556569966 17447751 complement(7726434..7727219) 1 NC_022657.1 COG4326 Sporulation control protein; hypothetical protein 7727219 17447751 AFR_35410 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738391.1 7726434 R 1246995 CDS YP_008738392.1 556569967 17447752 7727475..7728488 1 NC_022657.1 COG0568 DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32); RNA polymerase principal sigma factor hrdB 7728488 17447752 AFR_35415 Actinoplanes friuliensis DSM 7358 RNA polymerase principal sigma factor hrdB YP_008738392.1 7727475 D 1246995 CDS YP_008738393.1 556569968 17447753 7728582..7728935 1 NC_022657.1 hypothetical protein 7728935 17447753 AFR_35420 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738393.1 7728582 D 1246995 CDS YP_008738394.1 556569969 17447754 complement(7730294..7732822) 1 NC_022657.1 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; putative acyl-CoA synthetase 7732822 17447754 AFR_35425 Actinoplanes friuliensis DSM 7358 putative acyl-CoA synthetase YP_008738394.1 7730294 R 1246995 CDS YP_008738395.1 556569970 17447755 complement(7732855..7734039) 1 NC_022657.1 COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein; hypothetical protein 7734039 17447755 AFR_35430 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738395.1 7732855 R 1246995 CDS YP_008738396.1 556569971 17447756 7734209..7734907 1 NC_022657.1 COG1321 Mn-dependent transcriptional regulator; Iron-dependent repressor ideR 7734907 17447756 AFR_35435 Actinoplanes friuliensis DSM 7358 Iron-dependent repressor ideR YP_008738396.1 7734209 D 1246995 CDS YP_008738397.1 556569972 17447757 complement(7734920..7735474) 1 NC_022657.1 hypothetical protein 7735474 17447757 AFR_35440 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738397.1 7734920 R 1246995 CDS YP_008738398.1 556569973 17447758 complement(7735539..7735772) 1 NC_022657.1 hypothetical protein 7735772 17447758 AFR_35445 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738398.1 7735539 R 1246995 CDS YP_008738399.1 556569974 17447759 7735832..7736287 1 NC_022657.1 hypothetical protein 7736287 17447759 AFR_35450 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738399.1 7735832 D 1246995 CDS YP_008738400.1 556569975 17447760 7736309..7737223 1 NC_022657.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); hypothetical protein 7737223 17447760 AFR_35455 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738400.1 7736309 D 1246995 CDS YP_008738401.1 556569976 17447761 complement(7737233..7738447) 1 NC_022657.1 COG0477 Permeases of the major facilitator superfamily; Inner membrane protein ybjJ 7738447 17447761 AFR_35460 Actinoplanes friuliensis DSM 7358 Inner membrane protein ybjJ YP_008738401.1 7737233 R 1246995 CDS YP_008738402.1 556569977 17447762 complement(7738512..7739573) 1 NC_022657.1 hypothetical protein 7739573 17447762 AFR_35465 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738402.1 7738512 R 1246995 CDS YP_008738403.1 556569978 17447763 7739637..7740143 1 NC_022657.1 hypothetical protein 7740143 17447763 AFR_35470 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738403.1 7739637 D 1246995 CDS YP_008738404.1 556569979 17447764 complement(7740137..7740922) 1 NC_022657.1 COG2207 AraC-type DNA-binding domain-containing proteins; AraC family transcriptional regulator 7740922 17447764 AFR_35475 Actinoplanes friuliensis DSM 7358 AraC family transcriptional regulator YP_008738404.1 7740137 R 1246995 CDS YP_008738405.1 556569980 17447765 7740988..7741542 1 NC_022657.1 hypothetical protein 7741542 17447765 AFR_35480 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738405.1 7740988 D 1246995 CDS YP_008738406.1 556569981 17447766 complement(7741552..7742229) 1 NC_022657.1 hypothetical protein 7742229 17447766 AFR_35485 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738406.1 7741552 R 1246995 CDS YP_008738407.1 556569982 17447767 complement(7742226..7742990) 1 NC_022657.1 hypothetical protein 7742990 17447767 AFR_35490 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738407.1 7742226 R 1246995 CDS YP_008738408.1 556569983 17447768 7743327..7744991 1 NC_022657.1 lipase 7744991 17447768 AFR_35495 Actinoplanes friuliensis DSM 7358 lipase YP_008738408.1 7743327 D 1246995 CDS YP_008738409.1 556569984 17447769 complement(7745008..7745784) 1 NC_022657.1 hypothetical protein 7745784 17447769 AFR_35500 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738409.1 7745008 R 1246995 CDS YP_008738410.1 556569985 17447770 complement(7745986..7748880) 1 NC_022657.1 COG0209 Ribonucleotide reductase, alpha subunit; vitamin B12-dependent ribonucleotide reductase 7748880 17447770 AFR_35505 Actinoplanes friuliensis DSM 7358 vitamin B12-dependent ribonucleotide reductase YP_008738410.1 7745986 R 1246995 CDS YP_008738411.1 556569986 17447771 complement(7748910..7749440) 1 NC_022657.1 COG1327 Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains; putative ATP-binding protein 7749440 17447771 AFR_35510 Actinoplanes friuliensis DSM 7358 putative ATP-binding protein YP_008738411.1 7748910 R 1246995 CDS YP_008738412.1 556569987 17447772 complement(7749752..7750060) 1 NC_022657.1 COG1388 FOG: LysM repeat; hypothetical protein 7750060 17447772 AFR_35515 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738412.1 7749752 R 1246995 CDS YP_008738413.1 556569988 17447773 7750344..7751141 1 NC_022657.1 COG1974 SOS-response transcriptional repressors (RecA-mediated autopeptidases); putative SOS regulatory protein LexA 7751141 17447773 AFR_35520 Actinoplanes friuliensis DSM 7358 putative SOS regulatory protein LexA YP_008738413.1 7750344 D 1246995 CDS YP_008738414.1 556569989 17447774 complement(7751786..7752568) 1 NC_022657.1 transposase is4 family protein 7752568 17447774 AFR_35525 Actinoplanes friuliensis DSM 7358 transposase is4 family protein YP_008738414.1 7751786 R 1246995 CDS YP_008738415.1 556569990 17447775 complement(7753638..7755752) 1 NC_022657.1 hypothetical protein 7755752 17447775 AFR_35530 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738415.1 7753638 R 1246995 CDS YP_008738416.1 556569991 17447776 complement(7755840..7757231) 1 NC_022657.1 COG2262 GTPases; putative ATP/GTP-binding protein 7757231 17447776 AFR_35535 Actinoplanes friuliensis DSM 7358 putative ATP/GTP-binding protein YP_008738416.1 7755840 R 1246995 CDS YP_008738417.1 556569992 17447777 7757407..7758864 1 NC_022657.1 COG0281 Malic enzyme; putative malate dehydrogenase 7758864 17447777 AFR_35540 Actinoplanes friuliensis DSM 7358 putative malate dehydrogenase YP_008738417.1 7757407 D 1246995 CDS YP_008738418.1 556569993 17447778 complement(7759601..7760380) 1 NC_022657.1 COG0584 Glycerophosphoryl diester phosphodiesterase; putative glycerophosphoryl diester phosphodiesterase 7760380 17447778 AFR_35545 Actinoplanes friuliensis DSM 7358 putative glycerophosphoryl diester phosphodiesterase YP_008738418.1 7759601 R 1246995 CDS YP_008738419.1 556569994 17447779 complement(7760380..7761231) 1 NC_022657.1 COG0253 Diaminopimelate epimerase; diaminopimelate epimerase 7761231 dapF 17447779 dapF Actinoplanes friuliensis DSM 7358 diaminopimelate epimerase YP_008738419.1 7760380 R 1246995 CDS YP_008738420.1 556569995 17447780 complement(7761231..7762142) 1 NC_022657.1 COG0324 tRNA delta(2)-isopentenylpyrophosphate transferase; tRNA delta(2)-isopentenylpyrophosphate transferase 7762142 miaA 17447780 miaA Actinoplanes friuliensis DSM 7358 tRNA delta(2)-isopentenylpyrophosphate transferase YP_008738420.1 7761231 R 1246995 CDS YP_008738421.1 556569996 17447781 7762321..7763529 1 NC_022657.1 hypothetical protein 7763529 17447781 AFR_35560 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738421.1 7762321 D 1246995 CDS YP_008738422.1 556569997 17447782 complement(7763610..7764557) 1 NC_022657.1 COG1171 Threonine dehydratase; putative threonine dehydratase 7764557 17447782 AFR_35565 Actinoplanes friuliensis DSM 7358 putative threonine dehydratase YP_008738422.1 7763610 R 1246995 CDS YP_008738423.1 556569998 17447783 complement(7764565..7765026) 1 NC_022657.1 COG2346 Truncated hemoglobins; hypothetical protein 7765026 17447783 AFR_35570 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738423.1 7764565 R 1246995 CDS YP_008738424.1 556569999 17447784 7765082..7765417 1 NC_022657.1 COG1733 Predicted transcriptional regulators; HxlR family transcriptional regulator 7765417 17447784 AFR_35575 Actinoplanes friuliensis DSM 7358 HxlR family transcriptional regulator YP_008738424.1 7765082 D 1246995 CDS YP_008738425.1 556570000 17447785 complement(7765360..7766262) 1 NC_022657.1 COG0583 Transcriptional regulator; LysR family transcriptional regulator 7766262 17447785 AFR_35580 Actinoplanes friuliensis DSM 7358 LysR family transcriptional regulator YP_008738425.1 7765360 R 1246995 CDS YP_008738426.1 556570001 17447786 7766332..7767045 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); 3-oxoacyl-ACP reductase 7767045 17447786 AFR_35585 Actinoplanes friuliensis DSM 7358 3-oxoacyl-ACP reductase YP_008738426.1 7766332 D 1246995 CDS YP_008738427.1 556570002 17447787 complement(7767046..7768467) 1 NC_022657.1 COG2199 FOG: GGDEF domain; response regulator receiver modulated diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s) 7768467 17447787 AFR_35590 Actinoplanes friuliensis DSM 7358 response regulator receiver modulated diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s) YP_008738427.1 7767046 R 1246995 CDS YP_008738428.1 556570003 17447788 complement(7768508..7769998) 1 NC_022657.1 COG0621 2-methylthioadenine synthetase; (dimethylallyl)adenosine tRNA methylthiotransferase 7769998 17447788 AFR_35595 Actinoplanes friuliensis DSM 7358 (dimethylallyl)adenosine tRNA methylthiotransferase YP_008738428.1 7768508 R 1246995 CDS YP_008738429.1 556570004 17447789 complement(7770020..7770400) 1 NC_022657.1 hypothetical protein 7770400 17447789 AFR_35600 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738429.1 7770020 R 1246995 CDS YP_008738430.1 556570005 17447790 7770645..7771391 1 NC_022657.1 COG1126 ABC-type polar amino acid transport system, ATPase component; putative glutamate ABC transporter ATP-binding protein 7771391 17447790 AFR_35605 Actinoplanes friuliensis DSM 7358 putative glutamate ABC transporter ATP-binding protein YP_008738430.1 7770645 D 1246995 CDS YP_008738431.1 556570006 17447791 7771518..7772375 1 NC_022657.1 COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; putative glutamate ABC transporter substrate-binding protein 7772375 17447791 AFR_35610 Actinoplanes friuliensis DSM 7358 putative glutamate ABC transporter substrate-binding protein YP_008738431.1 7771518 D 1246995 CDS YP_008738432.1 556570007 17447792 7772456..7773130 1 NC_022657.1 COG0765 ABC-type amino acid transport system, permease component; putative glutamate ABC transporter permease 7773130 17447792 AFR_35615 Actinoplanes friuliensis DSM 7358 putative glutamate ABC transporter permease YP_008738432.1 7772456 D 1246995 CDS YP_008738433.1 556570008 17447793 7773127..7774005 1 NC_022657.1 COG0765 ABC-type amino acid transport system, permease component; putative glutamate ABC transporter permease 7774005 17447793 AFR_35620 Actinoplanes friuliensis DSM 7358 putative glutamate ABC transporter permease YP_008738433.1 7773127 D 1246995 CDS YP_008738434.1 556570009 17447794 complement(7774051..7774272) 1 NC_022657.1 COG1942 Uncharacterized protein, 4-oxalocrotonate tautomerase homolog; 4-oxalocrotonate tautomerase 7774272 17447794 AFR_35625 Actinoplanes friuliensis DSM 7358 4-oxalocrotonate tautomerase YP_008738434.1 7774051 R 1246995 CDS YP_008738435.1 556570010 17447795 7774384..7775208 1 NC_022657.1 COG1396 Predicted transcriptional regulators; XRE family transcriptional regulator 7775208 17447795 AFR_35630 Actinoplanes friuliensis DSM 7358 XRE family transcriptional regulator YP_008738435.1 7774384 D 1246995 CDS YP_008738436.1 556570011 17447796 complement(7776253..7777977) 1 NC_022657.1 COG1418 Predicted HD superfamily hydrolase; putative metal-dependent phosphohydrolase 7777977 17447796 AFR_35635 Actinoplanes friuliensis DSM 7358 putative metal-dependent phosphohydrolase YP_008738436.1 7776253 R 1246995 CDS YP_008738437.1 556570012 17447797 complement(7778353..7779819) 1 NC_022657.1 hypothetical protein 7779819 17447797 AFR_35640 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738437.1 7778353 R 1246995 CDS YP_008738438.1 556570013 17447798 complement(7780296..7781105) 1 NC_022657.1 extracellular serine protease 7781105 17447798 AFR_35645 Actinoplanes friuliensis DSM 7358 extracellular serine protease YP_008738438.1 7780296 R 1246995 CDS YP_008738439.1 556570014 17447799 complement(7782129..7782554) 1 NC_022657.1 COG2137 Uncharacterized protein conserved in bacteria; regulatory protein RecX 7782554 17447799 AFR_35650 Actinoplanes friuliensis DSM 7358 regulatory protein RecX YP_008738439.1 7782129 R 1246995 CDS YP_008738440.1 556570015 17447800 complement(7783865..7784911) 1 NC_022657.1 COG0468 RecA/RadA recombinase; recombinase A 7784911 recA 17447800 recA Actinoplanes friuliensis DSM 7358 recombinase A YP_008738440.1 7783865 R 1246995 CDS YP_008738441.1 556570016 17447801 complement(7785114..7785314) 1 NC_022657.1 hypothetical protein 7785314 17447801 AFR_35660 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738441.1 7785114 R 1246995 CDS YP_008738442.1 556570017 17447802 7785574..7786089 1 NC_022657.1 regulatory protein 7786089 17447802 AFR_35665 Actinoplanes friuliensis DSM 7358 regulatory protein YP_008738442.1 7785574 D 1246995 CDS YP_008738443.1 556570018 17447803 complement(7786061..7786723) 1 NC_022657.1 COG1573 Uracil-DNA glycosylase; bacteriophage-type DNA polymerase 7786723 17447803 AFR_35670 Actinoplanes friuliensis DSM 7358 bacteriophage-type DNA polymerase YP_008738443.1 7786061 R 1246995 CDS YP_008738444.1 556570019 17447804 7787182..7789575 1 NC_022657.1 COG0209 Ribonucleotide reductase, alpha subunit; ribonucleoside-diphosphate reductase subunit alpha 7789575 17447804 AFR_35675 Actinoplanes friuliensis DSM 7358 ribonucleoside-diphosphate reductase subunit alpha YP_008738444.1 7787182 D 1246995 CDS YP_008738445.1 556570020 17447805 7789594..7790571 1 NC_022657.1 COG0208 Ribonucleotide reductase, beta subunit; ribonucleoside-diphosphate reductase 7790571 17447805 AFR_35680 Actinoplanes friuliensis DSM 7358 ribonucleoside-diphosphate reductase YP_008738445.1 7789594 D 1246995 CDS YP_008738446.1 556570021 17447806 complement(7790652..7791998) 1 NC_022657.1 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs; GntR family transcriptional regulator 7791998 17447806 AFR_35685 Actinoplanes friuliensis DSM 7358 GntR family transcriptional regulator YP_008738446.1 7790652 R 1246995 CDS YP_008738447.1 556570022 17447807 7792046..7793284 1 NC_022657.1 COG3467 Predicted flavin-nucleotide-binding protein; hypothetical protein 7793284 17447807 AFR_35690 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738447.1 7792046 D 1246995 CDS YP_008738448.1 556570023 17447808 complement(7793348..7793833) 1 NC_022657.1 COG2259 Predicted membrane protein; hypothetical protein 7793833 17447808 AFR_35695 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738448.1 7793348 R 1246995 CDS YP_008738449.1 556570024 17447809 7794095..7794748 1 NC_022657.1 COG1280 Putative threonine efflux protein; leucine export protein LeuE 7794748 17447809 AFR_35700 Actinoplanes friuliensis DSM 7358 leucine export protein LeuE YP_008738449.1 7794095 D 1246995 CDS YP_008738450.1 556570025 17447810 complement(7795539..7796300) 1 NC_022657.1 COG4326 Sporulation control protein; hypothetical protein 7796300 17447810 AFR_35705 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738450.1 7795539 R 1246995 CDS YP_008738451.1 556570026 17447811 complement(7796315..7797370) 1 NC_022657.1 COG1253 Hemolysins and related proteins containing CBS domains; hypothetical protein 7797370 17447811 AFR_35710 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738451.1 7796315 R 1246995 CDS YP_008738452.1 556570027 17447812 complement(7797367..7798698) 1 NC_022657.1 COG1253 Hemolysins and related proteins containing CBS domains; hypothetical protein 7798698 17447812 AFR_35715 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738452.1 7797367 R 1246995 CDS YP_008738453.1 556570028 17447813 complement(7798845..7800365) 1 NC_022657.1 COG2234 Predicted aminopeptidases; putative M28-family peptidase 7800365 17447813 AFR_35720 Actinoplanes friuliensis DSM 7358 putative M28-family peptidase YP_008738453.1 7798845 R 1246995 CDS YP_008738454.1 556570029 17447814 complement(7800475..7802229) 1 NC_022657.1 COG0515 Serine/threonine protein kinase; putative serine/threonine protein kinase 7802229 17447814 AFR_35725 Actinoplanes friuliensis DSM 7358 putative serine/threonine protein kinase YP_008738454.1 7800475 R 1246995 CDS YP_008738455.1 556570030 17447815 complement(7802293..7802973) 1 NC_022657.1 COG3764 Sortase (surface protein transpeptidase); peptidase C60 sortase A and B 7802973 17447815 AFR_35730 Actinoplanes friuliensis DSM 7358 peptidase C60 sortase A and B YP_008738455.1 7802293 R 1246995 CDS YP_008738456.1 556570031 17447816 complement(7803033..7803836) 1 NC_022657.1 LPXTG-motif cell wall anchor domain-containing protein 7803836 17447816 AFR_35735 Actinoplanes friuliensis DSM 7358 LPXTG-motif cell wall anchor domain-containing protein YP_008738456.1 7803033 R 1246995 CDS YP_008738457.1 556570032 17447817 7804167..7808699 1 NC_022657.1 COG1201 Lhr-like helicases; putative ATP-dependent DNA helicase 7808699 17447817 AFR_35740 Actinoplanes friuliensis DSM 7358 putative ATP-dependent DNA helicase YP_008738457.1 7804167 D 1246995 CDS YP_008738458.1 556570033 17447818 7808903..7809802 1 NC_022657.1 hypothetical protein 7809802 17447818 AFR_35745 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738458.1 7808903 D 1246995 CDS YP_008738459.1 556570034 17447819 complement(7809786..7810310) 1 NC_022657.1 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins; acetyltransferase 7810310 17447819 AFR_35750 Actinoplanes friuliensis DSM 7358 acetyltransferase YP_008738459.1 7809786 R 1246995 CDS YP_008738460.1 556570035 17447820 complement(7810354..7811283) 1 NC_022657.1 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases; putative luciferase-like monooxygenase 7811283 17447820 AFR_35755 Actinoplanes friuliensis DSM 7358 putative luciferase-like monooxygenase YP_008738460.1 7810354 R 1246995 CDS YP_008738461.1 556570036 17447821 7811366..7812151 1 NC_022657.1 COG1912 Uncharacterized conserved protein; hypothetical protein 7812151 17447821 AFR_35760 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738461.1 7811366 D 1246995 CDS YP_008738462.1 556570037 17447822 complement(7812160..7812897) 1 NC_022657.1 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; hypothetical protein 7812897 17447822 AFR_35765 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738462.1 7812160 R 1246995 CDS YP_008738463.1 556570038 17447823 complement(7812914..7813534) 1 NC_022657.1 hypothetical protein 7813534 17447823 AFR_35770 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738463.1 7812914 R 1246995 CDS YP_008738464.1 556570039 17447824 7813643..7816567 1 NC_022657.1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; winged helix family transcriptional regulator 7816567 17447824 AFR_35775 Actinoplanes friuliensis DSM 7358 winged helix family transcriptional regulator YP_008738464.1 7813643 D 1246995 CDS YP_008738465.1 556570040 17447825 7816554..7817345 1 NC_022657.1 COG0266 Formamidopyrimidine-DNA glycosylase; putative formamidopyrimidine-DNA glycosylase 7817345 17447825 AFR_35780 Actinoplanes friuliensis DSM 7358 putative formamidopyrimidine-DNA glycosylase YP_008738465.1 7816554 D 1246995 CDS YP_008738466.1 556570041 17447826 complement(7817342..7818103) 1 NC_022657.1 hypothetical protein 7818103 17447826 AFR_35785 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738466.1 7817342 R 1246995 CDS YP_008738467.1 556570042 17447827 complement(7818132..7818998) 1 NC_022657.1 COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription; hypothetical protein 7818998 17447827 AFR_35790 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738467.1 7818132 R 1246995 CDS YP_008738468.1 556570043 17447828 complement(7819218..7819688) 1 NC_022657.1 COG1396 Predicted transcriptional regulators; XRE family transcriptional regulator 7819688 17447828 AFR_35795 Actinoplanes friuliensis DSM 7358 XRE family transcriptional regulator YP_008738468.1 7819218 R 1246995 CDS YP_008738469.1 556570044 17447829 complement(7819914..7820375) 1 NC_022657.1 COG1546 Uncharacterized protein (competence- and mitomycin-induced); Putative competence-damage inducible protein 7820375 17447829 AFR_35800 Actinoplanes friuliensis DSM 7358 Putative competence-damage inducible protein YP_008738469.1 7819914 R 1246995 CDS YP_008738470.1 556570045 17447830 complement(7820372..7820959) 1 NC_022657.1 COG0558 Phosphatidylglycerophosphate synthase; CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 7820959 17447830 AFR_35805 Actinoplanes friuliensis DSM 7358 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase YP_008738470.1 7820372 R 1246995 CDS YP_008738471.1 556570046 17447831 complement(7820956..7822353) 1 NC_022657.1 COG0621 2-methylthioadenine synthetase; MiaB-like tRNA modifying enzyme YliG 7822353 17447831 AFR_35810 Actinoplanes friuliensis DSM 7358 MiaB-like tRNA modifying enzyme YliG YP_008738471.1 7820956 R 1246995 CDS YP_008738472.1 556570047 17447832 7822538..7823953 1 NC_022657.1 COG5542 Predicted integral membrane protein; hypothetical protein 7823953 17447832 AFR_35815 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738472.1 7822538 D 1246995 CDS YP_008738473.1 556570048 17447833 complement(7825220..7827526) 1 NC_022657.1 COG1674 DNA segregation ATPase FtsK/SpoIIIE and related proteins; putative DNA translocase FtsK 7827526 17447833 AFR_35820 Actinoplanes friuliensis DSM 7358 putative DNA translocase FtsK YP_008738473.1 7825220 R 1246995 CDS YP_008738474.1 556570049 17447834 7827834..7828247 1 NC_022657.1 hypothetical protein 7828247 17447834 AFR_35825 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738474.1 7827834 D 1246995 CDS YP_008738475.1 556570050 17447835 complement(7828221..7828610) 1 NC_022657.1 hypothetical protein 7828610 17447835 AFR_35830 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738475.1 7828221 R 1246995 CDS YP_008738476.1 556570051 17447836 complement(7828694..7830016) 1 NC_022657.1 putative serine protease 7830016 17447836 AFR_35835 Actinoplanes friuliensis DSM 7358 putative serine protease YP_008738476.1 7828694 R 1246995 CDS YP_008738477.1 556570052 17447837 complement(7830130..7831818) 1 NC_022657.1 COG0595 Predicted hydrolase of the metallo-beta-lactamase superfamily; putative hydrolase 7831818 17447837 AFR_35840 Actinoplanes friuliensis DSM 7358 putative hydrolase YP_008738477.1 7830130 R 1246995 CDS YP_008738478.1 556570053 17447838 complement(7831832..7832737) 1 NC_022657.1 COG0329 Dihydrodipicolinate synthase/N-acetylneuraminate lyase; dihydrodipicolinate synthase 7832737 17447838 AFR_35845 Actinoplanes friuliensis DSM 7358 dihydrodipicolinate synthase YP_008738478.1 7831832 R 1246995 CDS YP_008738479.1 556570054 17447839 complement(7832801..7833322) 1 NC_022657.1 hypothetical protein 7833322 17447839 AFR_35850 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738479.1 7832801 R 1246995 CDS YP_008738480.1 556570055 17447840 complement(7833310..7834551) 1 NC_022657.1 COG3214 Uncharacterized protein conserved in bacteria; hypothetical protein 7834551 17447840 AFR_35855 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738480.1 7833310 R 1246995 CDS YP_008738481.1 556570056 17447841 7834592..7835113 1 NC_022657.1 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; yuaI-like N-acetyltransferase 7835113 17447841 AFR_35860 Actinoplanes friuliensis DSM 7358 yuaI-like N-acetyltransferase YP_008738481.1 7834592 D 1246995 CDS YP_008738482.1 556570057 17447842 7835124..7835678 1 NC_022657.1 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; putative GCN5-related N-acetyltransferase 7835678 17447842 AFR_35865 Actinoplanes friuliensis DSM 7358 putative GCN5-related N-acetyltransferase YP_008738482.1 7835124 D 1246995 CDS YP_008738483.1 556570058 17447843 complement(7835675..7836505) 1 NC_022657.1 COG0395 ABC-type sugar transport system, permease component; sugar transporter permease 7836505 17447843 AFR_35870 Actinoplanes friuliensis DSM 7358 sugar transporter permease YP_008738483.1 7835675 R 1246995 CDS YP_008738484.1 556570059 17447844 complement(7836505..7837530) 1 NC_022657.1 COG1175 ABC-type sugar transport systems, permease components; binding-protein-dependent transporter inner membrane component 7837530 17447844 AFR_35875 Actinoplanes friuliensis DSM 7358 binding-protein-dependent transporter inner membrane component YP_008738484.1 7836505 R 1246995 CDS YP_008738485.1 556570060 17447845 complement(7837533..7838771) 1 NC_022657.1 COG1653 ABC-type sugar transport system, periplasmic component; family 1 extracellular solute-binding protein 7838771 17447845 AFR_35880 Actinoplanes friuliensis DSM 7358 family 1 extracellular solute-binding protein YP_008738485.1 7837533 R 1246995 CDS YP_008738486.1 556570061 17447846 complement(7838781..7839761) 1 NC_022657.1 COG1609 Transcriptional regulators; LacI family transcriptional regulator 7839761 17447846 AFR_35885 Actinoplanes friuliensis DSM 7358 LacI family transcriptional regulator YP_008738486.1 7838781 R 1246995 CDS YP_008738487.1 556570062 17447847 7839888..7841909 1 NC_022657.1 COG3408 Glycogen debranching enzyme; hypothetical protein 7841909 17447847 AFR_35890 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738487.1 7839888 D 1246995 CDS YP_008738488.1 556570063 17447848 complement(7841934..7842638) 1 NC_022657.1 COG0289 Dihydrodipicolinate reductase; dihydrodipicolinate reductase 7842638 17447848 AFR_35895 Actinoplanes friuliensis DSM 7358 dihydrodipicolinate reductase YP_008738488.1 7841934 R 1246995 CDS YP_008738489.1 556570064 17447849 complement(7842697..7843599) 1 NC_022657.1 COG0671 Membrane-associated phospholipid phosphatase; hypothetical protein 7843599 17447849 AFR_35900 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738489.1 7842697 R 1246995 CDS YP_008738490.1 556570065 17447850 complement(7843686..7845158) 1 NC_022657.1 COG0612 Predicted Zn-dependent peptidases; putative M16-family peptidase 7845158 17447850 AFR_35905 Actinoplanes friuliensis DSM 7358 putative M16-family peptidase YP_008738490.1 7843686 R 1246995 CDS YP_008738491.1 556570066 17447851 complement(7845031..7847364) 1 NC_022657.1 COG1185 Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase); polynucleotide phosphorylase/polyadenylase 7847364 17447851 AFR_35910 Actinoplanes friuliensis DSM 7358 polynucleotide phosphorylase/polyadenylase YP_008738491.1 7845031 R 1246995 CDS YP_008738492.1 556570067 17447852 complement(7847558..7847827) 1 NC_022657.1 COG0184 Ribosomal protein S15P/S13E; 30S ribosomal protein S15 7847827 17447852 AFR_35915 Actinoplanes friuliensis DSM 7358 30S ribosomal protein S15 YP_008738492.1 7847558 R 1246995 CDS YP_008738493.1 556570068 17447853 complement(7847963..7848907) 1 NC_022657.1 COG0196 FAD synthase; putative riboflavin kinase 7848907 17447853 AFR_35920 Actinoplanes friuliensis DSM 7358 putative riboflavin kinase YP_008738493.1 7847963 R 1246995 CDS YP_008738494.1 556570069 17447854 7848990..7851641 1 NC_022657.1 COG0642 Signal transduction histidine kinase; integral membrane sensor hybrid histidine kinase 7851641 17447854 AFR_35925 Actinoplanes friuliensis DSM 7358 integral membrane sensor hybrid histidine kinase YP_008738494.1 7848990 D 1246995 CDS YP_008738495.1 556570070 17447855 7851928..7852047 1 NC_022657.1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; response regulator mprA 7852047 17447855 AFR_35930 Actinoplanes friuliensis DSM 7358 response regulator mprA YP_008738495.1 7851928 D 1246995 CDS YP_008738496.1 556570071 17447856 complement(7852034..7852915) 1 NC_022657.1 COG0130 Pseudouridine synthase; tRNA pseudouridine synthase B 7852915 truB 17447856 truB Actinoplanes friuliensis DSM 7358 tRNA pseudouridine synthase B YP_008738496.1 7852034 R 1246995 CDS YP_008738497.1 556570072 17447857 complement(7852951..7853400) 1 NC_022657.1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; hypothetical protein 7853400 17447857 AFR_35940 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738497.1 7852951 R 1246995 CDS YP_008738498.1 556570073 17447858 7853438..7854334 1 NC_022657.1 COG1846 Transcriptional regulators; MarR family transcriptional regulator 7854334 17447858 AFR_35945 Actinoplanes friuliensis DSM 7358 MarR family transcriptional regulator YP_008738498.1 7853438 D 1246995 CDS YP_008738499.1 556570074 17447859 complement(7855022..7856341) 1 NC_022657.1 COG0534 Na+-driven multidrug efflux pump; Multidrug resistance protein mdtK 7856341 17447859 AFR_35950 Actinoplanes friuliensis DSM 7358 Multidrug resistance protein mdtK YP_008738499.1 7855022 R 1246995 CDS YP_008738500.1 556570075 17447860 complement(7856783..7857814) 1 NC_022657.1 COG0618 Exopolyphosphatase-related proteins; hypothetical protein 7857814 17447860 AFR_35955 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738500.1 7856783 R 1246995 CDS YP_008738501.1 556570076 17447861 complement(7857811..7858278) 1 NC_022657.1 COG0858 Ribosome-binding factor A; ribosome-binding factor A 7858278 rbfA 17447861 rbfA Actinoplanes friuliensis DSM 7358 ribosome-binding factor A YP_008738501.1 7857811 R 1246995 CDS YP_008738502.1 556570077 17447862 complement(7858404..7858697) 1 NC_022657.1 COG1550 Uncharacterized protein conserved in bacteria; hypothetical protein 7858697 17447862 AFR_35965 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738502.1 7858404 R 1246995 CDS YP_008738503.1 556570078 17447863 complement(7858731..7859756) 1 NC_022657.1 COG0863 DNA modification methylase; hypothetical protein 7859756 17447863 AFR_35970 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738503.1 7858731 R 1246995 CDS YP_008738504.1 556570079 17447864 complement(7859819..7862887) 1 NC_022657.1 COG0532 Translation initiation factor 2 (IF-2; GTPase); translation initiation factor IF-2 7862887 infB 17447864 infB Actinoplanes friuliensis DSM 7358 translation initiation factor IF-2 YP_008738504.1 7859819 R 1246995 CDS YP_008738505.1 556570080 17447865 complement(7862979..7863317) 1 NC_022657.1 COG2740 Predicted nucleic-acid-binding protein implicated in transcription termination; hypothetical protein 7863317 17447865 AFR_35980 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738505.1 7862979 R 1246995 CDS YP_008738506.1 556570081 17447866 complement(7863358..7864374) 1 NC_022657.1 COG0195 Transcription elongation factor; transcription elongation factor NusA 7864374 nusA 17447866 nusA Actinoplanes friuliensis DSM 7358 transcription elongation factor NusA YP_008738506.1 7863358 R 1246995 CDS YP_008738507.1 556570082 17447867 complement(7864371..7865039) 1 NC_022657.1 COG0779 Uncharacterized protein conserved in bacteria; hypothetical protein 7865039 17447867 AFR_35990 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738507.1 7864371 R 1246995 CDS YP_008738508.1 556570083 17447868 7865255..7865710 1 NC_022657.1 hypothetical protein 7865710 17447868 AFR_35995 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738508.1 7865255 D 1246995 CDS YP_008738509.1 556570084 17447869 7865707..7866129 1 NC_022657.1 hypothetical protein 7866129 17447869 AFR_36000 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738509.1 7865707 D 1246995 CDS YP_008738510.1 556570085 17447870 7866147..7866857 1 NC_022657.1 hypothetical protein 7866857 17447870 AFR_36005 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738510.1 7866147 D 1246995 CDS YP_008738511.1 556570086 17447871 complement(7866861..7867553) 1 NC_022657.1 COG1814 Uncharacterized membrane protein; Fe(2+)/(Mn2+) transporter pcl1 7867553 17447871 AFR_36010 Actinoplanes friuliensis DSM 7358 Fe(2+)/(Mn2+) transporter pcl1 YP_008738511.1 7866861 R 1246995 CDS YP_008738512.1 556570087 17447872 complement(7867550..7868407) 1 NC_022657.1 COG0024 Methionine aminopeptidase; putative methionine aminopeptidase 7868407 17447872 AFR_36015 Actinoplanes friuliensis DSM 7358 putative methionine aminopeptidase YP_008738512.1 7867550 R 1246995 CDS YP_008738513.1 556570088 17447873 7868527..7868850 1 NC_022657.1 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); sulfate transporter/antisigma-factor antagonist 7868850 17447873 AFR_36020 Actinoplanes friuliensis DSM 7358 sulfate transporter/antisigma-factor antagonist YP_008738513.1 7868527 D 1246995 CDS YP_008738514.1 556570089 17447874 complement(7868837..7872502) 1 NC_022657.1 COG2202 FOG: PAS/PAC domain; stage II sporulation protein E 7872502 17447874 AFR_36025 Actinoplanes friuliensis DSM 7358 stage II sporulation protein E YP_008738514.1 7868837 R 1246995 CDS YP_008738515.1 556570090 17447875 7872555..7873124 1 NC_022657.1 hypothetical protein 7873124 17447875 AFR_36030 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738515.1 7872555 D 1246995 CDS YP_008738516.1 556570091 17447876 complement(7873127..7873864) 1 NC_022657.1 COG2071 Predicted glutamine amidotransferases; putative glutamine amidotransferase 7873864 17447876 AFR_36035 Actinoplanes friuliensis DSM 7358 putative glutamine amidotransferase YP_008738516.1 7873127 R 1246995 CDS YP_008738517.1 556570092 17447877 complement(7873927..7874622) 1 NC_022657.1 COG2071 Predicted glutamine amidotransferases; putative glutamine amidotransferase 7874622 17447877 AFR_36040 Actinoplanes friuliensis DSM 7358 putative glutamine amidotransferase YP_008738517.1 7873927 R 1246995 CDS YP_008738518.1 556570093 17447878 complement(7874832..7875596) 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); short chain dehydrogenase 7875596 17447878 AFR_36045 Actinoplanes friuliensis DSM 7358 short chain dehydrogenase YP_008738518.1 7874832 R 1246995 CDS YP_008738519.1 556570094 17447879 complement(7875607..7876968) 1 NC_022657.1 COG1012 NAD-dependent aldehyde dehydrogenases; betaine aldehyde dehydrogenase 7876968 17447879 AFR_36050 Actinoplanes friuliensis DSM 7358 betaine aldehyde dehydrogenase YP_008738519.1 7875607 R 1246995 CDS YP_008738520.1 556570095 17447880 complement(7877004..7878350) 1 NC_022657.1 COG0174 Glutamine synthetase; glutamine synthetase 7878350 17447880 AFR_36055 Actinoplanes friuliensis DSM 7358 glutamine synthetase YP_008738520.1 7877004 R 1246995 CDS YP_008738521.1 556570096 17447881 complement(7878409..7879935) 1 NC_022657.1 COG0531 Amino acid transporters; putative amino acid permease 7879935 17447881 AFR_36060 Actinoplanes friuliensis DSM 7358 putative amino acid permease YP_008738521.1 7878409 R 1246995 CDS YP_008738522.1 556570097 17447882 7880664..7881062 1 NC_022657.1 COG0789 Predicted transcriptional regulators; putative heavy metal-dependent transcriptional regulator 7881062 17447882 AFR_36065 Actinoplanes friuliensis DSM 7358 putative heavy metal-dependent transcriptional regulator YP_008738522.1 7880664 D 1246995 CDS YP_008738523.1 556570098 17447883 complement(7881619..7882458) 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); short-chain dehydrogenase/reductase SDR 7882458 17447883 AFR_36070 Actinoplanes friuliensis DSM 7358 short-chain dehydrogenase/reductase SDR YP_008738523.1 7881619 R 1246995 CDS YP_008738524.1 556570099 17447884 7882604..7883230 1 NC_022657.1 hypothetical protein 7883230 17447884 AFR_36075 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738524.1 7882604 D 1246995 CDS YP_008738525.1 556570100 17447885 7883164..7883688 1 NC_022657.1 COG0640 Predicted transcriptional regulators; hypothetical protein 7883688 17447885 AFR_36080 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738525.1 7883164 D 1246995 CDS YP_008738526.1 556570101 17447886 7883724..7885127 1 NC_022657.1 COG1680 Beta-lactamase class C and other penicillin binding proteins; beta-lactamase class C-like protein 7885127 17447886 AFR_36085 Actinoplanes friuliensis DSM 7358 beta-lactamase class C-like protein YP_008738526.1 7883724 D 1246995 CDS YP_008738527.1 556570102 17447887 7885802..7887157 1 NC_022657.1 COG4585 Signal transduction histidine kinase; putative two-component system sensor kinase 7887157 17447887 AFR_36090 Actinoplanes friuliensis DSM 7358 putative two-component system sensor kinase YP_008738527.1 7885802 D 1246995 CDS YP_008738528.1 556570103 17447888 7887154..7887816 1 NC_022657.1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; Nitrate/nitrite response regulator protein narP 7887816 17447888 AFR_36095 Actinoplanes friuliensis DSM 7358 Nitrate/nitrite response regulator protein narP YP_008738528.1 7887154 D 1246995 CDS YP_008738529.1 556570104 17447889 7887883..7888776 1 NC_022657.1 COG4152 ABC-type uncharacterized transport system, ATPase component; putative ABC transporter ATP-binding protein 7888776 17447889 AFR_36100 Actinoplanes friuliensis DSM 7358 putative ABC transporter ATP-binding protein YP_008738529.1 7887883 D 1246995 CDS YP_008738530.1 556570105 17447890 7888773..7889840 1 NC_022657.1 COG1668 ABC-type Na+ efflux pump, permease component; hypothetical protein 7889840 17447890 AFR_36105 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738530.1 7888773 D 1246995 CDS YP_008738531.1 556570106 17447891 complement(7889851..7890435) 1 NC_022657.1 COG1309 Transcriptional regulator; putative TetR-family transcriptional regulator 7890435 17447891 AFR_36110 Actinoplanes friuliensis DSM 7358 putative TetR-family transcriptional regulator YP_008738531.1 7889851 R 1246995 CDS YP_008738532.1 556570107 17447892 complement(7890441..7892585) 1 NC_022657.1 COG1511 Predicted membrane protein; ABC transporter permease 7892585 17447892 AFR_36115 Actinoplanes friuliensis DSM 7358 ABC transporter permease YP_008738532.1 7890441 R 1246995 CDS YP_008738533.1 556570108 17447893 complement(7892582..7893289) 1 NC_022657.1 COG1121 ABC-type Mn/Zn transport systems, ATPase component; spermidine/putrescine import ATP-binding protein potA 7893289 17447893 AFR_36120 Actinoplanes friuliensis DSM 7358 spermidine/putrescine import ATP-binding protein potA YP_008738533.1 7892582 R 1246995 CDS YP_008738534.1 556570109 17447894 7893350..7894384 1 NC_022657.1 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases; putative luciferase-like monooxygenase 7894384 17447894 AFR_36125 Actinoplanes friuliensis DSM 7358 putative luciferase-like monooxygenase YP_008738534.1 7893350 D 1246995 CDS YP_008738535.1 556570110 17447895 complement(7894381..7895220) 1 NC_022657.1 COG3393 Predicted acetyltransferase; putative GCN5-related N-acetyltransferase 7895220 17447895 AFR_36130 Actinoplanes friuliensis DSM 7358 putative GCN5-related N-acetyltransferase YP_008738535.1 7894381 R 1246995 CDS YP_008738536.1 556570111 17447896 7895360..7895938 1 NC_022657.1 COG1695 Predicted transcriptional regulators; putative PadR-like family transcriptional regulator 7895938 17447896 AFR_36135 Actinoplanes friuliensis DSM 7358 putative PadR-like family transcriptional regulator YP_008738536.1 7895360 D 1246995 CDS YP_008738537.1 556570112 17447897 complement(7897128..7898300) 1 NC_022657.1 COG0821 Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 7898300 ispG 17447897 ispG Actinoplanes friuliensis DSM 7358 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase YP_008738537.1 7897128 R 1246995 CDS YP_008738538.1 556570113 17447898 complement(7898311..7899570) 1 NC_022657.1 COG0750 Predicted membrane-associated Zn-dependent proteases 1; putative M50-family peptidase 7899570 17447898 AFR_36145 Actinoplanes friuliensis DSM 7358 putative M50-family peptidase YP_008738538.1 7898311 R 1246995 CDS YP_008738539.1 556570114 17447899 complement(7899570..7900760) 1 NC_022657.1 COG0743 1-deoxy-D-xylulose 5-phosphate reductoisomerase; putative 1-deoxy-D-xylulose 5-phosphate reductoisomerase 7900760 17447899 AFR_36150 Actinoplanes friuliensis DSM 7358 putative 1-deoxy-D-xylulose 5-phosphate reductoisomerase YP_008738539.1 7899570 R 1246995 CDS YP_008738540.1 556570115 17447900 complement(7900795..7901334) 1 NC_022657.1 hypothetical protein 7901334 17447900 AFR_36155 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738540.1 7900795 R 1246995 CDS YP_008738541.1 556570116 17447901 7901468..7902316 1 NC_022657.1 hypothetical protein 7902316 17447901 AFR_36160 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738541.1 7901468 D 1246995 CDS YP_008738542.1 556570117 17447902 complement(7902189..7904318) 1 NC_022657.1 COG2409 Predicted drug exporters of the RND superfamily; MMPL domain-containing protein 7904318 17447902 AFR_36165 Actinoplanes friuliensis DSM 7358 MMPL domain-containing protein YP_008738542.1 7902189 R 1246995 CDS YP_008738543.1 556570118 17447903 7904425..7905132 1 NC_022657.1 COG1309 Transcriptional regulator; TetR family transcriptional regulator 7905132 17447903 AFR_36170 Actinoplanes friuliensis DSM 7358 TetR family transcriptional regulator YP_008738543.1 7904425 D 1246995 CDS YP_008738544.1 556570119 17447904 7905144..7906739 1 NC_022657.1 COG1233 Phytoene dehydrogenase and related proteins; putative oxidoreductase 7906739 17447904 AFR_36175 Actinoplanes friuliensis DSM 7358 putative oxidoreductase YP_008738544.1 7905144 D 1246995 CDS YP_008738545.1 556570120 17447905 complement(7908383..7909927) 1 NC_022657.1 COG2220 Predicted Zn-dependent hydrolases of the beta-lactamase fold; hypothetical protein 7909927 17447905 AFR_36180 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738545.1 7908383 R 1246995 CDS YP_008738546.1 556570121 17447906 7910060..7910287 1 NC_022657.1 hypothetical protein 7910287 17447906 AFR_36185 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738546.1 7910060 D 1246995 CDS YP_008738547.1 556570122 17447907 complement(7910343..7911407) 1 NC_022657.1 Protein piccolo 7911407 17447907 AFR_36190 Actinoplanes friuliensis DSM 7358 Protein piccolo YP_008738547.1 7910343 R 1246995 CDS YP_008738548.1 556570123 17447908 complement(7911448..7912626) 1 NC_022657.1 COG0820 Predicted Fe-S-cluster redox enzyme; ribosomal RNA large subunit methyltransferase N 7912626 17447908 AFR_36195 Actinoplanes friuliensis DSM 7358 ribosomal RNA large subunit methyltransferase N YP_008738548.1 7911448 R 1246995 CDS YP_008738549.1 556570124 17447909 complement(7912661..7913824) 1 NC_022657.1 COG0575 CDP-diglyceride synthetase; putative phosphatidate cytidylyltransferase 7913824 17447909 AFR_36200 Actinoplanes friuliensis DSM 7358 putative phosphatidate cytidylyltransferase YP_008738549.1 7912661 R 1246995 CDS YP_008738550.1 556570125 17447910 complement(7913824..7914381) 1 NC_022657.1 COG0233 Ribosome recycling factor; ribosome recycling factor 7914381 frr 17447910 frr Actinoplanes friuliensis DSM 7358 ribosome recycling factor YP_008738550.1 7913824 R 1246995 CDS YP_008738551.1 556570126 17447911 complement(7914440..7915204) 1 NC_022657.1 COG0528 Uridylate kinase; putative uridylate kinase 7915204 17447911 AFR_36210 Actinoplanes friuliensis DSM 7358 putative uridylate kinase YP_008738551.1 7914440 R 1246995 CDS YP_008738552.1 556570127 17447912 complement(7915307..7916137) 1 NC_022657.1 COG0264 Translation elongation factor Ts; elongation factor Ts 7916137 tsf 17447912 tsf Actinoplanes friuliensis DSM 7358 elongation factor Ts YP_008738552.1 7915307 R 1246995 CDS YP_008738553.1 556570128 17447913 complement(7916212..7917159) 1 NC_022657.1 COG0052 Ribosomal protein S2; 30S ribosomal protein S2 7917159 rpsB 17447913 rpsB Actinoplanes friuliensis DSM 7358 30S ribosomal protein S2 YP_008738553.1 7916212 R 1246995 CDS YP_008738554.1 556570129 17447914 complement(7917476..7918180) 1 NC_022657.1 hypothetical protein 7918180 17447914 AFR_36225 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738554.1 7917476 R 1246995 CDS YP_008738555.1 556570130 17447915 7918368..7918685 1 NC_022657.1 COG0792 Predicted endonuclease distantly related to archaeal Holliday junction resolvase; hypothetical protein 7918685 17447915 AFR_36230 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738555.1 7918368 D 1246995 CDS YP_008738556.1 556570131 17447916 7918701..7920218 1 NC_022657.1 COG0606 Predicted ATPase with chaperone activity; hypothetical protein 7920218 17447916 AFR_36235 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738556.1 7918701 D 1246995 CDS YP_008738557.1 556570132 17447917 7920202..7921377 1 NC_022657.1 COG0758 Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake; hypothetical protein 7921377 17447917 AFR_36240 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738557.1 7920202 D 1246995 CDS YP_008738558.1 556570133 17447918 complement(7921383..7921568) 1 NC_022657.1 COG3311 Predicted transcriptional regulator; putative regulatory protein 7921568 17447918 AFR_36245 Actinoplanes friuliensis DSM 7358 putative regulatory protein YP_008738558.1 7921383 R 1246995 CDS YP_008738559.1 556570134 17447919 7922740..7922934 1 NC_022657.1 hypothetical protein 7922934 17447919 AFR_36250 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738559.1 7922740 D 1246995 CDS YP_008738560.1 556570135 17447920 7923148..7923552 1 NC_022657.1 COG2188 Transcriptional regulators; Putative transcriptional regulator of 2-aminoethylphosphonate degradation operons 7923552 17447920 AFR_36255 Actinoplanes friuliensis DSM 7358 Putative transcriptional regulator of 2-aminoethylphosphonate degradation operons YP_008738560.1 7923148 D 1246995 CDS YP_008738561.1 556570136 17447921 7924158..7924940 1 NC_022657.1 transposase is4 family protein 7924940 17447921 AFR_36260 Actinoplanes friuliensis DSM 7358 transposase is4 family protein YP_008738561.1 7924158 D 1246995 CDS YP_008738562.1 556570137 17447922 complement(7925760..7926215) 1 NC_022657.1 hypothetical protein 7926215 17447922 AFR_36265 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738562.1 7925760 R 1246995 CDS YP_008738563.1 556570138 17447923 7926248..7927165 1 NC_022657.1 COG0582 Integrase; putative integrase/recombinase 7927165 17447923 AFR_36270 Actinoplanes friuliensis DSM 7358 putative integrase/recombinase YP_008738563.1 7926248 D 1246995 CDS YP_008738564.1 556570139 17447924 7927202..7928389 1 NC_022657.1 COG0520 Selenocysteine lyase; putative aminotransferase 7928389 17447924 AFR_36275 Actinoplanes friuliensis DSM 7358 putative aminotransferase YP_008738564.1 7927202 D 1246995 CDS YP_008738565.1 556570140 17447925 complement(7928398..7928772) 1 NC_022657.1 COG0739 Membrane proteins related to metalloendopeptidases; peptidase M23B 7928772 17447925 AFR_36280 Actinoplanes friuliensis DSM 7358 peptidase M23B YP_008738565.1 7928398 R 1246995 CDS YP_008738566.1 556570141 17447926 complement(7928972..7929298) 1 NC_022657.1 hypothetical protein 7929298 17447926 AFR_36285 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738566.1 7928972 R 1246995 CDS YP_008738567.1 556570142 17447927 complement(7929295..7930113) 1 NC_022657.1 COG0164 Ribonuclease HII; ribonuclease H 7930113 17447927 AFR_36290 Actinoplanes friuliensis DSM 7358 ribonuclease H YP_008738567.1 7929295 R 1246995 CDS YP_008738568.1 556570143 17447928 complement(7930113..7930559) 1 NC_022657.1 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; putative NUDIX hydrolase 7930559 17447928 AFR_36295 Actinoplanes friuliensis DSM 7358 putative NUDIX hydrolase YP_008738568.1 7930113 R 1246995 CDS YP_008738569.1 556570144 17447929 complement(7930601..7931251) 1 NC_022657.1 COG0681 Signal peptidase I; signal peptidase I 7931251 17447929 AFR_36300 Actinoplanes friuliensis DSM 7358 signal peptidase I YP_008738569.1 7930601 R 1246995 CDS YP_008738570.1 556570145 17447930 complement(7931248..7932087) 1 NC_022657.1 COG0681 Signal peptidase I; putative signal peptidase I 7932087 17447930 AFR_36305 Actinoplanes friuliensis DSM 7358 putative signal peptidase I YP_008738570.1 7931248 R 1246995 CDS YP_008738571.1 556570146 17447931 complement(7932358..7932717) 1 NC_022657.1 COG0335 Ribosomal protein L19; 50S ribosomal protein L19 7932717 17447931 AFR_36310 Actinoplanes friuliensis DSM 7358 50S ribosomal protein L19 YP_008738571.1 7932358 R 1246995 CDS YP_008738572.1 556570147 17447932 complement(7932845..7933609) 1 NC_022657.1 COG0336 tRNA-(guanine-N1)-methyltransferase; tRNA (guanine37-N1)-methyltransferase 7933609 trmD 17447932 trmD Actinoplanes friuliensis DSM 7358 tRNA (guanine37-N1)-methyltransferase YP_008738572.1 7932845 R 1246995 CDS YP_008738573.1 556570148 17447933 complement(7933620..7934189) 1 NC_022657.1 COG0806 RimM protein, required for 16S rRNA processing; 16S rRNA-processing protein RimM 7934189 rimM 17447933 rimM Actinoplanes friuliensis DSM 7358 16S rRNA-processing protein RimM YP_008738573.1 7933620 R 1246995 CDS YP_008738574.1 556570149 17447934 complement(7934201..7934458) 1 NC_022657.1 COG1837 Predicted RNA-binding protein (contains KH domain); hypothetical protein 7934458 17447934 AFR_36325 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738574.1 7934201 R 1246995 CDS YP_008738575.1 556570150 17447935 complement(7934436..7934999) 1 NC_022657.1 COG0228 Ribosomal protein S16; 30S ribosomal protein S16 7934999 rpsP 17447935 rpsP Actinoplanes friuliensis DSM 7358 30S ribosomal protein S16 YP_008738575.1 7934436 R 1246995 CDS YP_008738576.1 556570151 17447936 complement(7935357..7935998) 1 NC_022657.1 hypothetical protein 7935998 17447936 AFR_36335 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738576.1 7935357 R 1246995 CDS YP_008738577.1 556570152 17447937 complement(7936044..7936694) 1 NC_022657.1 hypothetical protein 7936694 17447937 AFR_36340 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738577.1 7936044 R 1246995 CDS YP_008738578.1 556570153 17447938 complement(7936697..7938103) 1 NC_022657.1 COG0442 Prolyl-tRNA synthetase; prolyl-tRNA ligase 7938103 17447938 AFR_36345 Actinoplanes friuliensis DSM 7358 prolyl-tRNA ligase YP_008738578.1 7936697 R 1246995 CDS YP_008738579.1 556570154 17447939 7938183..7938686 1 NC_022657.1 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; putative RNA polymerase ECF-subfamily sigma factor 7938686 17447939 AFR_36350 Actinoplanes friuliensis DSM 7358 putative RNA polymerase ECF-subfamily sigma factor YP_008738579.1 7938183 D 1246995 CDS YP_008738580.1 556570155 17447940 7938676..7940082 1 NC_022657.1 COG1520 FOG: WD40-like repeat; hypothetical protein 7940082 17447940 AFR_36355 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738580.1 7938676 D 1246995 CDS YP_008738581.1 556570156 17447941 complement(7940085..7941161) 1 NC_022657.1 COG1228 Imidazolonepropionase and related amidohydrolases; hypothetical protein 7941161 17447941 AFR_36360 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738581.1 7940085 R 1246995 CDS YP_008738582.1 556570157 17447942 complement(7941187..7941807) 1 NC_022657.1 COG4636 Uncharacterized protein conserved in cyanobacteria; hypothetical protein 7941807 17447942 AFR_36365 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738582.1 7941187 R 1246995 CDS YP_008738583.1 556570158 17447943 complement(7941841..7943394) 1 NC_022657.1 COG0541 Signal recognition particle GTPase; signal recognition particle protein 7943394 17447943 AFR_36370 Actinoplanes friuliensis DSM 7358 signal recognition particle protein YP_008738583.1 7941841 R 1246995 CDS YP_008738584.1 556570159 17447944 complement(7943459..7943698) 1 NC_022657.1 hypothetical protein 7943698 17447944 AFR_36375 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738584.1 7943459 R 1246995 CDS YP_008738585.1 556570160 17447945 7944027..7945883 1 NC_022657.1 hypothetical protein 7945883 17447945 AFR_36380 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738585.1 7944027 D 1246995 CDS YP_008738586.1 556570161 17447946 7945912..7947174 1 NC_022657.1 COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase; NDP-N-acetyl-D-galactosaminuronic acid dehydrogenase 7947174 17447946 AFR_36385 Actinoplanes friuliensis DSM 7358 NDP-N-acetyl-D-galactosaminuronic acid dehydrogenase YP_008738586.1 7945912 D 1246995 CDS YP_008738587.1 556570162 17447947 7947171..7949258 1 NC_022657.1 COG1835 Predicted acyltransferases; putative acyltransferase 7949258 17447947 AFR_36390 Actinoplanes friuliensis DSM 7358 putative acyltransferase YP_008738587.1 7947171 D 1246995 CDS YP_008738588.1 556570163 17447948 7949500..7949988 1 NC_022657.1 COG2340 Uncharacterized protein with SCP/PR1 domains; hypothetical protein 7949988 17447948 AFR_36395 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738588.1 7949500 D 1246995 CDS YP_008738589.1 556570164 17447949 complement(7950076..7951113) 1 NC_022657.1 COG4122 Predicted O-methyltransferase; hypothetical protein 7951113 17447949 AFR_36400 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738589.1 7950076 R 1246995 CDS YP_008738590.1 556570165 17447950 complement(7951201..7953708) 1 NC_022657.1 COG0463 Glycosyltransferases involved in cell wall biogenesis; putative glycosyltransferase 7953708 17447950 AFR_36405 Actinoplanes friuliensis DSM 7358 putative glycosyltransferase YP_008738590.1 7951201 R 1246995 CDS YP_008738591.1 556570166 17447951 complement(7953672..7954562) 1 NC_022657.1 COG3739 Uncharacterized integral membrane protein; hypothetical protein 7954562 17447951 AFR_36410 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738591.1 7953672 R 1246995 CDS YP_008738592.1 556570167 17447952 complement(7954559..7956814) 1 NC_022657.1 COG2844 UTP:GlnB (protein PII) uridylyltransferase; PII uridylyl-transferase 7956814 17447952 AFR_36415 Actinoplanes friuliensis DSM 7358 PII uridylyl-transferase YP_008738592.1 7954559 R 1246995 CDS YP_008738593.1 556570168 17447953 complement(7956861..7957199) 1 NC_022657.1 COG0347 Nitrogen regulatory protein PII; putative nitrogen regulatory protein P-II 7957199 17447953 AFR_36420 Actinoplanes friuliensis DSM 7358 putative nitrogen regulatory protein P-II YP_008738593.1 7956861 R 1246995 CDS YP_008738594.1 556570169 17447954 complement(7957233..7958588) 1 NC_022657.1 COG0004 Ammonia permease; Ammonium transporter 1 member 2 7958588 17447954 AFR_36425 Actinoplanes friuliensis DSM 7358 Ammonium transporter 1 member 2 YP_008738594.1 7957233 R 1246995 CDS YP_008738595.1 556570170 17447955 complement(7958834..7959631) 1 NC_022657.1 COG0510 Predicted choline kinase involved in LPS biosynthesis; putative phosphotransferase 7959631 17447955 AFR_36430 Actinoplanes friuliensis DSM 7358 putative phosphotransferase YP_008738595.1 7958834 R 1246995 CDS YP_008738596.1 556570171 17447956 complement(7959683..7960831) 1 NC_022657.1 COG0552 Signal recognition particle GTPase; signal recognition particle-docking protein FtsY 7960831 17447956 AFR_36435 Actinoplanes friuliensis DSM 7358 signal recognition particle-docking protein FtsY YP_008738596.1 7959683 R 1246995 CDS YP_008738597.1 556570172 17447957 7960983..7962674 1 NC_022657.1 COG3540 Phosphodiesterase/alkaline phosphatase D; hypothetical protein 7962674 17447957 AFR_36440 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738597.1 7960983 D 1246995 CDS YP_008738598.1 556570173 17447958 7962706..7963227 1 NC_022657.1 hypothetical protein 7963227 17447958 AFR_36445 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738598.1 7962706 D 1246995 CDS YP_008738599.1 556570174 17447959 7963227..7963532 1 NC_022657.1 hypothetical protein 7963532 17447959 AFR_36450 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738599.1 7963227 D 1246995 CDS YP_008738600.1 556570175 17447960 complement(7963693..7964319) 1 NC_022657.1 hypothetical protein 7964319 17447960 AFR_36455 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738600.1 7963693 R 1246995 CDS YP_008738601.1 556570176 17447961 complement(7964355..7964822) 1 NC_022657.1 hypothetical protein 7964822 17447961 AFR_36460 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738601.1 7964355 R 1246995 CDS YP_008738602.1 556570177 17447962 7964830..7965174 1 NC_022657.1 hypothetical protein 7965174 17447962 AFR_36465 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738602.1 7964830 D 1246995 CDS YP_008738603.1 556570178 17447963 complement(7965141..7966007) 1 NC_022657.1 hypothetical protein 7966007 17447963 AFR_36470 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738603.1 7965141 R 1246995 CDS YP_008738604.1 556570179 17447964 complement(7966000..7966512) 1 NC_022657.1 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; ECF subfamily RNA polymerase sigma-24 subunit 7966512 17447964 AFR_36475 Actinoplanes friuliensis DSM 7358 ECF subfamily RNA polymerase sigma-24 subunit YP_008738604.1 7966000 R 1246995 CDS YP_008738605.1 556570180 17447965 complement(7966674..7967291) 1 NC_022657.1 COG1011 Predicted hydrolase (HAD superfamily); putative haloacid dehalogenase-like hydrolase 7967291 17447965 AFR_36480 Actinoplanes friuliensis DSM 7358 putative haloacid dehalogenase-like hydrolase YP_008738605.1 7966674 R 1246995 CDS YP_008738606.1 556570181 17447966 complement(7967298..7970879) 1 NC_022657.1 COG1196 Chromosome segregation ATPases; Chromosome partition protein smc 7970879 17447966 AFR_36485 Actinoplanes friuliensis DSM 7358 Chromosome partition protein smc YP_008738606.1 7967298 R 1246995 CDS YP_008738607.1 556570182 17447967 complement(7971143..7971337) 1 NC_022657.1 hypothetical protein 7971337 17447967 AFR_36490 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738607.1 7971143 R 1246995 CDS YP_008738608.1 556570183 17447968 7971771..7972508 1 NC_022657.1 COG2340 Uncharacterized protein with SCP/PR1 domains; hypothetical protein 7972508 17447968 AFR_36495 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738608.1 7971771 D 1246995 CDS YP_008738609.1 556570184 17447969 7972600..7974093 1 NC_022657.1 COG0438 Glycosyltransferase; Glycogen synthase 7974093 17447969 AFR_36500 Actinoplanes friuliensis DSM 7358 Glycogen synthase YP_008738609.1 7972600 D 1246995 CDS YP_008738610.1 556570185 17447970 7974090..7975268 1 NC_022657.1 hypothetical protein 7975268 17447970 AFR_36505 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738610.1 7974090 D 1246995 CDS YP_008738611.1 556570186 17447971 7975265..7975852 1 NC_022657.1 Spherulin-4 7975852 17447971 AFR_36510 Actinoplanes friuliensis DSM 7358 Spherulin-4 YP_008738611.1 7975265 D 1246995 CDS YP_008738612.1 556570187 17447972 complement(7975788..7976642) 1 NC_022657.1 COG0266 Formamidopyrimidine-DNA glycosylase; formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA glycosylase 7976642 17447972 AFR_36515 Actinoplanes friuliensis DSM 7358 formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA glycosylase YP_008738612.1 7975788 R 1246995 CDS YP_008738613.1 556570188 17447973 complement(7976665..7977843) 1 NC_022657.1 COG5542 Predicted integral membrane protein; hypothetical protein 7977843 17447973 AFR_36520 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738613.1 7976665 R 1246995 CDS YP_008738614.1 556570189 17447974 complement(7977840..7978625) 1 NC_022657.1 COG0571 dsRNA-specific ribonuclease; putative ribonuclease III 7978625 17447974 AFR_36525 Actinoplanes friuliensis DSM 7358 putative ribonuclease III YP_008738614.1 7977840 R 1246995 CDS YP_008738615.1 556570190 17447975 complement(7978622..7979683) 1 NC_022657.1 COG0416 Fatty acid/phospholipid biosynthesis enzyme; putative fatty acid synthesis protein 7979683 17447975 AFR_36530 Actinoplanes friuliensis DSM 7358 putative fatty acid synthesis protein YP_008738615.1 7978622 R 1246995 CDS YP_008738616.1 556570191 17447976 complement(7979694..7979867) 1 NC_022657.1 COG0333 Ribosomal protein L32; 50S ribosomal protein L32 7979867 rpmF 17447976 rpmF Actinoplanes friuliensis DSM 7358 50S ribosomal protein L32 YP_008738616.1 7979694 R 1246995 CDS YP_008738617.1 556570192 17447977 complement(7979880..7980437) 1 NC_022657.1 COG1399 Predicted metal-binding, possibly nucleic acid-binding protein; hypothetical protein 7980437 17447977 AFR_36540 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738617.1 7979880 R 1246995 CDS YP_008738618.1 556570193 17447978 complement(7980519..7981016) 1 NC_022657.1 COG3599 Cell division initiation protein; hypothetical protein 7981016 17447978 AFR_36545 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738618.1 7980519 R 1246995 CDS YP_008738619.1 556570194 17447979 complement(7981108..7981587) 1 NC_022657.1 COG0669 Phosphopantetheine adenylyltransferase; phosphopantetheine adenylyltransferase 7981587 coaD 17447979 coaD Actinoplanes friuliensis DSM 7358 phosphopantetheine adenylyltransferase YP_008738619.1 7981108 R 1246995 CDS YP_008738620.1 556570195 17447980 complement(7981584..7982159) 1 NC_022657.1 COG0742 N6-adenine-specific methylase; putative methyltransferase 7982159 17447980 AFR_36555 Actinoplanes friuliensis DSM 7358 putative methyltransferase YP_008738620.1 7981584 R 1246995 CDS YP_008738621.1 556570196 17447981 7982512..7983489 1 NC_022657.1 cell wall anchor domain-containing protein 7983489 17447981 AFR_36560 Actinoplanes friuliensis DSM 7358 cell wall anchor domain-containing protein YP_008738621.1 7982512 D 1246995 CDS YP_008738622.1 556570197 17447982 7983819..7985312 1 NC_022657.1 COG0417 DNA polymerase elongation subunit (family B); hypothetical protein 7985312 17447982 AFR_36565 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738622.1 7983819 D 1246995 CDS YP_008738623.1 556570198 17447983 7985398..7986906 1 NC_022657.1 hypothetical protein 7986906 17447983 AFR_36570 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738623.1 7985398 D 1246995 CDS YP_008738624.1 556570199 17447984 complement(7986960..7987301) 1 NC_022657.1 COG3502 Uncharacterized protein conserved in bacteria; hypothetical protein 7987301 17447984 AFR_36575 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738624.1 7986960 R 1246995 CDS YP_008738625.1 556570200 17447985 complement(7987298..7989499) 1 NC_022657.1 COG1200 RecG-like helicase; ATP-dependent DNA helicase RecG 7989499 17447985 AFR_36580 Actinoplanes friuliensis DSM 7358 ATP-dependent DNA helicase RecG YP_008738625.1 7987298 R 1246995 CDS YP_008738626.1 556570201 17447986 complement(7989496..7991310) 1 NC_022657.1 COG1461 Predicted kinase related to dihydroxyacetone kinase; putative phosphatase 7991310 17447986 AFR_36585 Actinoplanes friuliensis DSM 7358 putative phosphatase YP_008738626.1 7989496 R 1246995 CDS YP_008738627.1 556570202 17447987 7991468..7991659 1 NC_022657.1 COG0227 Ribosomal protein L28; 50S ribosomal protein L28 7991659 rpmB 17447987 rpmB Actinoplanes friuliensis DSM 7358 50S ribosomal protein L28 YP_008738627.1 7991468 D 1246995 CDS YP_008738628.1 556570203 17447988 complement(7991721..7992188) 1 NC_022657.1 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; N-acetyltransferase GCN5 7992188 17447988 AFR_36595 Actinoplanes friuliensis DSM 7358 N-acetyltransferase GCN5 YP_008738628.1 7991721 R 1246995 CDS YP_008738629.1 556570204 17447989 complement(7992195..7993133) 1 NC_022657.1 COG0611 Thiamine monophosphate kinase; thiamine monophosphate kinase 7993133 17447989 AFR_36600 Actinoplanes friuliensis DSM 7358 thiamine monophosphate kinase YP_008738629.1 7992195 R 1246995 CDS YP_008738630.1 556570205 17447990 7993244..7993477 1 NC_022657.1 COG1522 Transcriptional regulators; putative HTH-type transcriptional regulator 7993477 17447990 AFR_36605 Actinoplanes friuliensis DSM 7358 putative HTH-type transcriptional regulator YP_008738630.1 7993244 D 1246995 CDS YP_008738631.1 556570206 17447991 7993479..7994120 1 NC_022657.1 hypothetical protein 7994120 17447991 AFR_36610 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738631.1 7993479 D 1246995 CDS YP_008738632.1 556570207 17447992 complement(7994136..7995239) 1 NC_022657.1 COG1181 D-alanine-D-alanine ligase and related ATP-grasp enzymes; D-alanyl-alanine synthetase A 7995239 ddl 17447992 ddl Actinoplanes friuliensis DSM 7358 D-alanyl-alanine synthetase A YP_008738632.1 7994136 R 1246995 CDS YP_008738633.1 556570208 17447993 7995394..7995885 1 NC_022657.1 COG2453 Predicted protein-tyrosine phosphatase; putative tyrosine phosphatase 7995885 17447993 AFR_36620 Actinoplanes friuliensis DSM 7358 putative tyrosine phosphatase YP_008738633.1 7995394 D 1246995 CDS YP_008738634.1 556570209 17447994 complement(7995926..7996621) 1 NC_022657.1 hypothetical protein 7996621 17447994 AFR_36625 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738634.1 7995926 R 1246995 CDS YP_008738635.1 556570210 17447995 complement(7996618..7997514) 1 NC_022657.1 COG1131 ABC-type multidrug transport system, ATPase component; ABC transporter-like protein 7997514 17447995 AFR_36630 Actinoplanes friuliensis DSM 7358 ABC transporter-like protein YP_008738635.1 7996618 R 1246995 CDS YP_008738636.1 556570211 17447996 complement(7997511..7997867) 1 NC_022657.1 COG1725 Predicted transcriptional regulators; GntR family transcriptional regulator 7997867 17447996 AFR_36635 Actinoplanes friuliensis DSM 7358 GntR family transcriptional regulator YP_008738636.1 7997511 R 1246995 CDS YP_008738637.1 556570212 17447997 complement(7997951..7998319) 1 NC_022657.1 hypothetical protein 7998319 17447997 AFR_36640 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738637.1 7997951 R 1246995 CDS YP_008738638.1 556570213 17447998 complement(7998316..7999419) 1 NC_022657.1 COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases; cystathionine gamma-lyase 7999419 17447998 AFR_36645 Actinoplanes friuliensis DSM 7358 cystathionine gamma-lyase YP_008738638.1 7998316 R 1246995 CDS YP_008738639.1 556570214 17447999 complement(7999416..8000396) 1 NC_022657.1 COG0240 Glycerol-3-phosphate dehydrogenase; glycerol-3-phosphate dehydrogenase (NAD(P)+) 8000396 17447999 AFR_36650 Actinoplanes friuliensis DSM 7358 glycerol-3-phosphate dehydrogenase (NAD(P)+) YP_008738639.1 7999416 R 1246995 CDS YP_008738640.1 556570215 17448000 complement(8000408..8001136) 1 NC_022657.1 COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase; putative acyltransferase 8001136 17448000 AFR_36655 Actinoplanes friuliensis DSM 7358 putative acyltransferase YP_008738640.1 8000408 R 1246995 CDS YP_008738641.1 556570216 17448001 8001270..8001941 1 NC_022657.1 COG1920 Uncharacterized conserved protein; hypothetical protein 8001941 17448001 AFR_36660 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738641.1 8001270 D 1246995 CDS YP_008738642.1 556570217 17448002 8001952..8002149 1 NC_022657.1 hypothetical protein 8002149 17448002 AFR_36665 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738642.1 8001952 D 1246995 CDS YP_008738643.1 556570218 17448003 8002192..8004462 1 NC_022657.1 COG0855 Polyphosphate kinase; polyphosphate kinase 8004462 17448003 AFR_36670 Actinoplanes friuliensis DSM 7358 polyphosphate kinase YP_008738643.1 8002192 D 1246995 CDS YP_008738644.1 556570219 17448004 8004465..8005349 1 NC_022657.1 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; NUDIX hydrolase 8005349 17448004 AFR_36675 Actinoplanes friuliensis DSM 7358 NUDIX hydrolase YP_008738644.1 8004465 D 1246995 CDS YP_008738645.1 556570220 17448005 complement(8005353..8005763) 1 NC_022657.1 hypothetical protein 8005763 17448005 AFR_36680 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738645.1 8005353 R 1246995 CDS YP_008738646.1 556570221 17448006 complement(8005885..8006775) 1 NC_022657.1 COG0776 Bacterial nucleoid DNA-binding protein; Integration host factor subunit beta 8006775 17448006 AFR_36685 Actinoplanes friuliensis DSM 7358 Integration host factor subunit beta YP_008738646.1 8005885 R 1246995 CDS YP_008738647.1 556570222 17448007 complement(8006952..8007539) 1 NC_022657.1 COG0066 3-isopropylmalate dehydratase small subunit; isopropylmalate isomerase small subunit 8007539 17448007 AFR_36690 Actinoplanes friuliensis DSM 7358 isopropylmalate isomerase small subunit YP_008738647.1 8006952 R 1246995 CDS YP_008738648.1 556570223 17448008 complement(8007555..8009000) 1 NC_022657.1 COG0065 3-isopropylmalate dehydratase large subunit; isopropylmalate isomerase large subunit 8009000 17448008 AFR_36695 Actinoplanes friuliensis DSM 7358 isopropylmalate isomerase large subunit YP_008738648.1 8007555 R 1246995 CDS YP_008738649.1 556570224 17448009 8009050..8009736 1 NC_022657.1 COG1414 Transcriptional regulator; HTH-type transcriptional repressor allR 8009736 17448009 AFR_36700 Actinoplanes friuliensis DSM 7358 HTH-type transcriptional repressor allR YP_008738649.1 8009050 D 1246995 CDS YP_008738650.1 556570225 17448010 complement(8009733..8010425) 1 NC_022657.1 COG0491 Zn-dependent hydrolases, including glyoxylases; putative hydrolase 8010425 17448010 AFR_36705 Actinoplanes friuliensis DSM 7358 putative hydrolase YP_008738650.1 8009733 R 1246995 CDS YP_008738651.1 556570226 17448013 complement(8010823..8011626) 1 NC_022657.1 COG0702 Predicted nucleoside-diphosphate-sugar epimerases; hypothetical protein 8011626 17448013 AFR_36710 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738651.1 8010823 R 1246995 CDS YP_008738652.1 556570227 17448014 8011683..8012471 1 NC_022657.1 COG1309 Transcriptional regulator; TetR family transcriptional regulator 8012471 17448014 AFR_36715 Actinoplanes friuliensis DSM 7358 TetR family transcriptional regulator YP_008738652.1 8011683 D 1246995 CDS YP_008738653.1 556570228 17448015 complement(8012426..8013229) 1 NC_022657.1 COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway); putative fumarylacetoacetate hydrolase family protein 8013229 17448015 AFR_36720 Actinoplanes friuliensis DSM 7358 putative fumarylacetoacetate hydrolase family protein YP_008738653.1 8012426 R 1246995 CDS YP_008738654.1 556570229 17448016 complement(8013272..8013520) 1 NC_022657.1 COG1476 Predicted transcriptional regulators; putative HTH-type transcriptional regulator 8013520 17448016 AFR_36725 Actinoplanes friuliensis DSM 7358 putative HTH-type transcriptional regulator YP_008738654.1 8013272 R 1246995 CDS YP_008738655.1 556570230 17448017 complement(8013528..8014355) 1 NC_022657.1 COG0842 ABC-type multidrug transport system, permease component; antibiotic transport system permease 8014355 17448017 AFR_36730 Actinoplanes friuliensis DSM 7358 antibiotic transport system permease YP_008738655.1 8013528 R 1246995 CDS YP_008738656.1 556570231 17448018 complement(8014373..8015278) 1 NC_022657.1 COG1131 ABC-type multidrug transport system, ATPase component; spermidine/putrescine import ATP-binding protein potA 8015278 17448018 AFR_36735 Actinoplanes friuliensis DSM 7358 spermidine/putrescine import ATP-binding protein potA YP_008738656.1 8014373 R 1246995 CDS YP_008738657.1 556570232 17448019 8015600..8016538 1 NC_022657.1 hypothetical protein 8016538 17448019 AFR_36740 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738657.1 8015600 D 1246995 CDS YP_008738658.1 556570233 17448020 8016544..8017383 1 NC_022657.1 COG2207 AraC-type DNA-binding domain-containing proteins; AraC family transcriptional regulator 8017383 17448020 AFR_36745 Actinoplanes friuliensis DSM 7358 AraC family transcriptional regulator YP_008738658.1 8016544 D 1246995 CDS YP_008738659.1 556570234 17448021 8017428..8018009 1 NC_022657.1 COG0262 Dihydrofolate reductase; hypothetical protein 8018009 17448021 AFR_36750 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738659.1 8017428 D 1246995 CDS YP_008738660.1 556570235 17448022 complement(8018013..8018450) 1 NC_022657.1 COG1186 Protein chain release factor B; hypothetical protein 8018450 17448022 AFR_36755 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738660.1 8018013 R 1246995 CDS YP_008738661.1 556570236 17448023 complement(8018754..8019653) 1 NC_022657.1 COG5006 Predicted permease, DMT superfamily; putative permease, DMT superfamily protein 8019653 17448023 AFR_36760 Actinoplanes friuliensis DSM 7358 putative permease, DMT superfamily protein YP_008738661.1 8018754 R 1246995 CDS YP_008738662.1 556570237 17448024 8019738..8020634 1 NC_022657.1 COG0583 Transcriptional regulator; LysR family transcriptional regulator 8020634 17448024 AFR_36765 Actinoplanes friuliensis DSM 7358 LysR family transcriptional regulator YP_008738662.1 8019738 D 1246995 CDS YP_008738663.1 556570238 17448025 complement(8020618..8021817) 1 NC_022657.1 COG0642 Signal transduction histidine kinase; histidine kinase 8021817 17448025 AFR_36770 Actinoplanes friuliensis DSM 7358 histidine kinase YP_008738663.1 8020618 R 1246995 CDS YP_008738664.1 556570239 17448026 complement(8021814..8022491) 1 NC_022657.1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; winged helix family two component transcriptional regulator 8022491 17448026 AFR_36775 Actinoplanes friuliensis DSM 7358 winged helix family two component transcriptional regulator YP_008738664.1 8021814 R 1246995 CDS YP_008738665.1 556570240 17448027 complement(8022499..8023359) 1 NC_022657.1 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain; peptidase S1 and S6, chymotrypsin/Hap 8023359 17448027 AFR_36780 Actinoplanes friuliensis DSM 7358 peptidase S1 and S6, chymotrypsin/Hap YP_008738665.1 8022499 R 1246995 CDS YP_008738666.1 556570241 17448028 complement(8023387..8024367) 1 NC_022657.1 COG2304 Uncharacterized protein containing a von Willebrand factor type A (vWA) domain; von willebrand factor type a 8024367 17448028 AFR_36785 Actinoplanes friuliensis DSM 7358 von willebrand factor type a YP_008738666.1 8023387 R 1246995 CDS YP_008738667.1 556570242 17448029 complement(8024364..8025329) 1 NC_022657.1 COG1721 Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain); hypothetical protein 8025329 17448029 AFR_36790 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738667.1 8024364 R 1246995 CDS YP_008738668.1 556570243 17448030 complement(8025391..8026410) 1 NC_022657.1 COG0714 MoxR-like ATPases; ATPase 8026410 17448030 AFR_36795 Actinoplanes friuliensis DSM 7358 ATPase YP_008738668.1 8025391 R 1246995 CDS YP_008738669.1 556570244 17448031 8026611..8027927 1 NC_022657.1 COG0612 Predicted Zn-dependent peptidases; putative M16-family peptidase 8027927 17448031 AFR_36800 Actinoplanes friuliensis DSM 7358 putative M16-family peptidase YP_008738669.1 8026611 D 1246995 CDS YP_008738670.1 556570245 17448032 8027924..8029270 1 NC_022657.1 COG0612 Predicted Zn-dependent peptidases; putative M16-family peptidase 8029270 17448032 AFR_36805 Actinoplanes friuliensis DSM 7358 putative M16-family peptidase YP_008738670.1 8027924 D 1246995 CDS YP_008738671.1 556570246 17448033 8029401..8030858 1 NC_022657.1 hypothetical protein 8030858 17448033 AFR_36810 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738671.1 8029401 D 1246995 CDS YP_008738672.1 556570247 17448034 8030917..8031915 1 NC_022657.1 COG3568 Metal-dependent hydrolase; hypothetical protein 8031915 17448034 AFR_36815 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738672.1 8030917 D 1246995 CDS YP_008738673.1 556570248 17448035 complement(8031896..8032507) 1 NC_022657.1 COG1309 Transcriptional regulator; TetR family transcriptional regulator 8032507 17448035 AFR_36820 Actinoplanes friuliensis DSM 7358 TetR family transcriptional regulator YP_008738673.1 8031896 R 1246995 CDS YP_008738674.1 556570249 17448036 8032590..8033459 1 NC_022657.1 COG1131 ABC-type multidrug transport system, ATPase component; ABC-type multidrug transport system, ATPase component 8033459 17448036 AFR_36825 Actinoplanes friuliensis DSM 7358 ABC-type multidrug transport system, ATPase component YP_008738674.1 8032590 D 1246995 CDS YP_008738675.1 556570250 17448037 8033481..8034221 1 NC_022657.1 COG0842 ABC-type multidrug transport system, permease component; ABC-2 type transporter 8034221 17448037 AFR_36830 Actinoplanes friuliensis DSM 7358 ABC-2 type transporter YP_008738675.1 8033481 D 1246995 CDS YP_008738676.1 556570251 17448038 complement(8034227..8035813) 1 NC_022657.1 COG0119 Isopropylmalate/homocitrate/citramalate synthases; alpha-isopropylmalate/homocitrate synthase family transferase 8035813 17448038 AFR_36835 Actinoplanes friuliensis DSM 7358 alpha-isopropylmalate/homocitrate synthase family transferase YP_008738676.1 8034227 R 1246995 CDS YP_008738677.1 556570252 17448039 8036030..8036767 1 NC_022657.1 COG2365 Protein tyrosine/serine phosphatase; hypothetical protein 8036767 17448039 AFR_36840 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738677.1 8036030 D 1246995 CDS YP_008738678.1 556570253 17448041 complement(8037681..8038778) 1 NC_022657.1 COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase; branched-chain amino acid aminotransferase 8038778 17448041 AFR_36855 Actinoplanes friuliensis DSM 7358 branched-chain amino acid aminotransferase YP_008738678.1 8037681 R 1246995 CDS YP_008738679.1 556570254 17448042 complement(8038933..8039964) 1 NC_022657.1 COG0473 Isocitrate/isopropylmalate dehydrogenase; putative 3-isopropylmalate dehydrogenase 8039964 17448042 AFR_36860 Actinoplanes friuliensis DSM 7358 putative 3-isopropylmalate dehydrogenase YP_008738679.1 8038933 R 1246995 CDS YP_008738680.1 556570255 17448043 8040331..8040693 1 NC_022657.1 hypothetical protein 8040693 17448043 AFR_36865 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738680.1 8040331 D 1246995 CDS YP_008738681.1 556570256 17448044 complement(8040690..8042291) 1 NC_022657.1 COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases; D-3-phosphoglycerate dehydrogenase 8042291 17448044 AFR_36870 Actinoplanes friuliensis DSM 7358 D-3-phosphoglycerate dehydrogenase YP_008738681.1 8040690 R 1246995 CDS YP_008738682.1 556570257 17448045 8042463..8043257 1 NC_022657.1 hypothetical protein 8043257 17448045 AFR_36875 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738682.1 8042463 D 1246995 CDS YP_008738683.1 556570258 17448046 complement(8043301..8044341) 1 NC_022657.1 mannosyl-3-phosphoglycerate synthase 8044341 17448046 AFR_36880 Actinoplanes friuliensis DSM 7358 mannosyl-3-phosphoglycerate synthase YP_008738683.1 8043301 R 1246995 CDS YP_008738684.1 556570259 17448047 complement(8044749..8045762) 1 NC_022657.1 COG0059 Ketol-acid reductoisomerase; ketol-acid reductoisomerase 8045762 17448047 AFR_36885 Actinoplanes friuliensis DSM 7358 ketol-acid reductoisomerase YP_008738684.1 8044749 R 1246995 CDS YP_008738685.1 556570260 17448048 complement(8045842..8046357) 1 NC_022657.1 COG0440 Acetolactate synthase, small (regulatory) subunit; acetolactate synthase 3 regulatory subunit 8046357 ilvH 17448048 ilvH Actinoplanes friuliensis DSM 7358 acetolactate synthase 3 regulatory subunit YP_008738685.1 8045842 R 1246995 CDS YP_008738686.1 556570261 17448049 complement(8046363..8048195) 1 NC_022657.1 COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]; acetolactate synthase 1 catalytic subunit 8048195 17448049 AFR_36895 Actinoplanes friuliensis DSM 7358 acetolactate synthase 1 catalytic subunit YP_008738686.1 8046363 R 1246995 CDS YP_008738687.1 556570262 17448050 complement(8048343..8050727) 1 NC_022657.1 COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain; Signaling protein ykoW 8050727 17448050 AFR_36900 Actinoplanes friuliensis DSM 7358 Signaling protein ykoW YP_008738687.1 8048343 R 1246995 CDS YP_008738688.1 556570263 17448051 8050874..8052721 1 NC_022657.1 COG0129 Dihydroxyacid dehydratase/phosphogluconate dehydratase; dihydroxy-acid dehydratase 8052721 17448051 AFR_36905 Actinoplanes friuliensis DSM 7358 dihydroxy-acid dehydratase YP_008738688.1 8050874 D 1246995 CDS YP_008738689.1 556570264 17448052 complement(8053296..8055701) 1 NC_022657.1 COG3250 Beta-galactosidase/beta-glucuronidase; beta-mannosidase 8055701 17448052 AFR_36910 Actinoplanes friuliensis DSM 7358 beta-mannosidase YP_008738689.1 8053296 R 1246995 CDS YP_008738690.1 556570265 17448053 complement(8055713..8056600) 1 NC_022657.1 COG0395 ABC-type sugar transport system, permease component; cellobiose ABC transporter permease 8056600 17448053 AFR_36915 Actinoplanes friuliensis DSM 7358 cellobiose ABC transporter permease YP_008738690.1 8055713 R 1246995 CDS YP_008738691.1 556570266 17448054 complement(8056597..8057598) 1 NC_022657.1 COG1175 ABC-type sugar transport systems, permease components; cellobiose ABC transporter permease 8057598 17448054 AFR_36920 Actinoplanes friuliensis DSM 7358 cellobiose ABC transporter permease YP_008738691.1 8056597 R 1246995 CDS YP_008738692.1 556570267 17448055 complement(8057661..8058944) 1 NC_022657.1 COG1653 ABC-type sugar transport system, periplasmic component; cellobiose ABC transporter solute-binding protein 8058944 17448055 AFR_36925 Actinoplanes friuliensis DSM 7358 cellobiose ABC transporter solute-binding protein YP_008738692.1 8057661 R 1246995 CDS YP_008738693.1 556570268 17448056 8059248..8060267 1 NC_022657.1 COG1609 Transcriptional regulators; putative LacI-family transcriptional regulator 8060267 17448056 AFR_36930 Actinoplanes friuliensis DSM 7358 putative LacI-family transcriptional regulator YP_008738693.1 8059248 D 1246995 CDS YP_008738694.1 556570269 17448057 complement(8060985..8063597) 1 NC_022657.1 COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain; putative diguanylate cyclase/phosphodiesterase with PAS sensor 8063597 17448057 AFR_36935 Actinoplanes friuliensis DSM 7358 putative diguanylate cyclase/phosphodiesterase with PAS sensor YP_008738694.1 8060985 R 1246995 CDS YP_008738695.1 556570270 17448058 complement(8063793..8064068) 1 NC_022657.1 COG1977 Molybdopterin converting factor, small subunit; putative molybdopterin synthase related protein 8064068 17448058 AFR_36940 Actinoplanes friuliensis DSM 7358 putative molybdopterin synthase related protein YP_008738695.1 8063793 R 1246995 CDS YP_008738696.1 556570271 17448059 complement(8064068..8065144) 1 NC_022657.1 hypothetical protein 8065144 17448059 AFR_36945 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738696.1 8064068 R 1246995 CDS YP_008738697.1 556570272 17448060 8065228..8065620 1 NC_022657.1 hypothetical protein 8065620 17448060 AFR_36950 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738697.1 8065228 D 1246995 CDS YP_008738698.1 556570273 17448061 complement(8065564..8066490) 1 NC_022657.1 COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases; d-isomer specific 2-hydroxyacid dehydrogenase nad-binding protein 8066490 17448061 AFR_36955 Actinoplanes friuliensis DSM 7358 d-isomer specific 2-hydroxyacid dehydrogenase nad-binding protein YP_008738698.1 8065564 R 1246995 CDS YP_008738699.1 556570274 17448062 8066598..8067776 1 NC_022657.1 COG2133 Glucose/sorbosone dehydrogenases; hypothetical protein 8067776 17448062 AFR_36960 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738699.1 8066598 D 1246995 CDS YP_008738700.1 556570275 17448063 8067846..8069426 1 NC_022657.1 COG1408 Predicted phosphohydrolases; putative metallophosphoesterase 8069426 17448063 AFR_36965 Actinoplanes friuliensis DSM 7358 putative metallophosphoesterase YP_008738700.1 8067846 D 1246995 CDS YP_008738701.1 556570276 17448064 complement(8069622..8071115) 1 NC_022657.1 COG0064 Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog); aspartyl/glutamyl-tRNA amidotransferase subunit B 8071115 gatB 17448064 gatB Actinoplanes friuliensis DSM 7358 aspartyl/glutamyl-tRNA amidotransferase subunit B YP_008738701.1 8069622 R 1246995 CDS YP_008738702.1 556570277 17448065 complement(8071112..8072605) 1 NC_022657.1 COG0154 Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases; aspartyl/glutamyl-tRNA amidotransferase subunit A 8072605 gatA 17448065 gatA Actinoplanes friuliensis DSM 7358 aspartyl/glutamyl-tRNA amidotransferase subunit A YP_008738702.1 8071112 R 1246995 CDS YP_008738703.1 556570278 17448066 complement(8072611..8072910) 1 NC_022657.1 COG0721 Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit; aspartyl-tRNA(Asn)/glutamyl-tRNA (Gln) amidotransferase subunit C 8072910 17448066 AFR_36980 Actinoplanes friuliensis DSM 7358 aspartyl-tRNA(Asn)/glutamyl-tRNA (Gln) amidotransferase subunit C YP_008738703.1 8072611 R 1246995 CDS YP_008738704.1 556570279 17448067 complement(8073163..8075292) 1 NC_022657.1 COG2199 FOG: GGDEF domain; Signaling protein ykoW 8075292 17448067 AFR_36985 Actinoplanes friuliensis DSM 7358 Signaling protein ykoW YP_008738704.1 8073163 R 1246995 CDS YP_008738705.1 556570280 17448068 8075311..8075772 1 NC_022657.1 hypothetical protein 8075772 17448068 AFR_36990 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738705.1 8075311 D 1246995 CDS YP_008738706.1 556570281 17448069 complement(8076118..8078352) 1 NC_022657.1 COG0272 NAD-dependent DNA ligase (contains BRCT domain type II); DNA ligase 8078352 17448069 AFR_36995 Actinoplanes friuliensis DSM 7358 DNA ligase YP_008738706.1 8076118 R 1246995 CDS YP_008738707.1 556570282 17448070 8078454..8078849 1 NC_022657.1 PemK family protein 8078849 17448070 AFR_37000 Actinoplanes friuliensis DSM 7358 PemK family protein YP_008738707.1 8078454 D 1246995 CDS YP_008738708.1 556570283 17448071 complement(8078851..8079204) 1 NC_022657.1 COG0346 Lactoylglutathione lyase and related lyases; glyoxalase/bleomycin resistance protein/dioxygenase 8079204 17448071 AFR_37005 Actinoplanes friuliensis DSM 7358 glyoxalase/bleomycin resistance protein/dioxygenase YP_008738708.1 8078851 R 1246995 CDS YP_008738709.1 556570284 17448072 complement(8079249..8080283) 1 NC_022657.1 hypothetical protein 8080283 17448072 AFR_37010 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738709.1 8079249 R 1246995 CDS YP_008738710.1 556570285 17448073 complement(8080240..8081319) 1 NC_022657.1 COG0482 Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain; tRNA-specific 2-thiouridylase MnmA 8081319 mnmA 17448073 mnmA Actinoplanes friuliensis DSM 7358 tRNA-specific 2-thiouridylase MnmA YP_008738710.1 8080240 R 1246995 CDS YP_008738711.1 556570286 17448074 complement(8082336..8083511) 1 NC_022657.1 COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes; putative aminotransferase 8083511 17448074 AFR_37020 Actinoplanes friuliensis DSM 7358 putative aminotransferase YP_008738711.1 8082336 R 1246995 CDS YP_008738712.1 556570287 17448075 complement(8083617..8084576) 1 NC_022657.1 COG2025 Electron transfer flavoprotein, alpha subunit; putative electron transfer flavoprotein subunit alpha 8084576 17448075 AFR_37025 Actinoplanes friuliensis DSM 7358 putative electron transfer flavoprotein subunit alpha YP_008738712.1 8083617 R 1246995 CDS YP_008738713.1 556570288 17448076 complement(8084591..8085370) 1 NC_022657.1 COG2086 Electron transfer flavoprotein, beta subunit; Protein fixA 8085370 17448076 AFR_37030 Actinoplanes friuliensis DSM 7358 Protein fixA YP_008738713.1 8084591 R 1246995 CDS YP_008738714.1 556570289 17448077 8085582..8085959 1 NC_022657.1 COG2149 Predicted membrane protein; Inner membrane protein yidH 8085959 17448077 AFR_37035 Actinoplanes friuliensis DSM 7358 Inner membrane protein yidH YP_008738714.1 8085582 D 1246995 CDS YP_008738715.1 556570290 17448078 8085974..8086276 1 NC_022657.1 hypothetical protein 8086276 17448078 AFR_37040 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738715.1 8085974 D 1246995 CDS YP_008738716.1 556570291 17448079 8086315..8086653 1 NC_022657.1 hypothetical protein 8086653 17448079 AFR_37045 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738716.1 8086315 D 1246995 CDS YP_008738717.1 556570292 17448080 complement(8086657..8088279) 1 NC_022657.1 COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]; hypothetical protein 8088279 17448080 AFR_37050 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738717.1 8086657 R 1246995 CDS YP_008738718.1 556570293 17448081 complement(8088345..8090138) 1 NC_022657.1 COG0443 Molecular chaperone; heat shock protein 70 8090138 17448081 AFR_37055 Actinoplanes friuliensis DSM 7358 heat shock protein 70 YP_008738718.1 8088345 R 1246995 CDS YP_008738719.1 556570294 17448082 complement(8090179..8090730) 1 NC_022657.1 hypothetical protein 8090730 17448082 AFR_37060 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738719.1 8090179 R 1246995 CDS YP_008738720.1 556570295 17448083 complement(8090803..8091576) 1 NC_022657.1 COG1024 Enoyl-CoA hydratase/carnithine racemase; putative enoyl-CoA hydratase/isomerase 8091576 17448083 AFR_37065 Actinoplanes friuliensis DSM 7358 putative enoyl-CoA hydratase/isomerase YP_008738720.1 8090803 R 1246995 CDS YP_008738721.1 556570296 17448084 8091665..8092135 1 NC_022657.1 hypothetical protein 8092135 17448084 AFR_37070 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738721.1 8091665 D 1246995 CDS YP_008738722.1 556570297 17448085 8092132..8092407 1 NC_022657.1 hypothetical protein 8092407 17448085 AFR_37075 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738722.1 8092132 D 1246995 CDS YP_008738723.1 556570298 17448086 8092471..8092809 1 NC_022657.1 COG4270 Predicted membrane protein; hypothetical protein 8092809 17448086 AFR_37080 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738723.1 8092471 D 1246995 CDS YP_008738724.1 556570299 17448087 complement(8092799..8093704) 1 NC_022657.1 COG0524 Sugar kinases, ribokinase family; putative PfkB-family carbohydrate kinase 8093704 17448087 AFR_37085 Actinoplanes friuliensis DSM 7358 putative PfkB-family carbohydrate kinase YP_008738724.1 8092799 R 1246995 CDS YP_008738725.1 556570300 17448088 complement(8093712..8094533) 1 NC_022657.1 COG1119 ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA; iron complex transport system ATP-binding protein 8094533 17448088 AFR_37090 Actinoplanes friuliensis DSM 7358 iron complex transport system ATP-binding protein YP_008738725.1 8093712 R 1246995 CDS YP_008738726.1 556570301 17448089 complement(8094575..8095753) 1 NC_022657.1 COG1940 Transcriptional regulator/sugar kinase; putative ROK-family transcriptional regulator 8095753 17448089 AFR_37095 Actinoplanes friuliensis DSM 7358 putative ROK-family transcriptional regulator YP_008738726.1 8094575 R 1246995 CDS YP_008738727.1 556570302 17448090 8095927..8097384 1 NC_022657.1 COG1472 Beta-glucosidase-related glycosidases; glycoside hydrolase family 3 domain-containing protein 8097384 17448090 AFR_37100 Actinoplanes friuliensis DSM 7358 glycoside hydrolase family 3 domain-containing protein YP_008738727.1 8095927 D 1246995 CDS YP_008738728.1 556570303 17448091 8097526..8098020 1 NC_022657.1 integral membrane protein 8098020 17448091 AFR_37105 Actinoplanes friuliensis DSM 7358 integral membrane protein YP_008738728.1 8097526 D 1246995 CDS YP_008738729.1 556570304 17448092 8098017..8098445 1 NC_022657.1 thiol-disulfide oxidoreductase dcc 8098445 17448092 AFR_37110 Actinoplanes friuliensis DSM 7358 thiol-disulfide oxidoreductase dcc YP_008738729.1 8098017 D 1246995 CDS YP_008738730.1 556570305 17448093 8098426..8099196 1 NC_022657.1 COG1309 Transcriptional regulator; TetR family transcriptional regulator 8099196 17448093 AFR_37115 Actinoplanes friuliensis DSM 7358 TetR family transcriptional regulator YP_008738730.1 8098426 D 1246995 CDS YP_008738731.1 556570306 17448094 complement(8099525..8101663) 1 NC_022657.1 COG2217 Cation transport ATPase; copper-translocating P-type ATPase 8101663 17448094 AFR_37120 Actinoplanes friuliensis DSM 7358 copper-translocating P-type ATPase YP_008738731.1 8099525 R 1246995 CDS YP_008738732.1 556570307 17448095 complement(8101660..8102253) 1 NC_022657.1 COG1309 Transcriptional regulator; TetR family transcriptional regulator 8102253 17448095 AFR_37125 Actinoplanes friuliensis DSM 7358 TetR family transcriptional regulator YP_008738732.1 8101660 R 1246995 CDS YP_008738733.1 556570308 17448096 8102327..8103118 1 NC_022657.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); hypothetical protein 8103118 17448096 AFR_37130 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738733.1 8102327 D 1246995 CDS YP_008738734.1 556570309 17448097 complement(8103152..8108116) 1 NC_022657.1 COG2902 NAD-specific glutamate dehydrogenase; putative NAD-specific glutamate dehydrogenase 8108116 17448097 AFR_37135 Actinoplanes friuliensis DSM 7358 putative NAD-specific glutamate dehydrogenase YP_008738734.1 8103152 R 1246995 CDS YP_008738735.1 556570310 17448098 8108330..8110258 1 NC_022657.1 COG0768 Cell division protein FtsI/penicillin-binding protein 2; putative penicillin-binding protein 8110258 17448098 AFR_37140 Actinoplanes friuliensis DSM 7358 putative penicillin-binding protein YP_008738735.1 8108330 D 1246995 CDS YP_008738736.1 556570311 17448099 complement(8110261..8113110) 1 NC_022657.1 COG0010 Arginase/agmatinase/formimionoglutamate hydrolase, arginase family; arginase 8113110 17448099 AFR_37145 Actinoplanes friuliensis DSM 7358 arginase YP_008738736.1 8110261 R 1246995 CDS YP_008738737.1 556570312 17448100 complement(8113129..8114043) 1 NC_022657.1 COG3118 Thioredoxin domain-containing protein; putative thioredoxin 8114043 17448100 AFR_37150 Actinoplanes friuliensis DSM 7358 putative thioredoxin YP_008738737.1 8113129 R 1246995 CDS YP_008738738.1 556570313 17448101 complement(8114119..8115048) 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); short chain dehydrogenase 8115048 17448101 AFR_37155 Actinoplanes friuliensis DSM 7358 short chain dehydrogenase YP_008738738.1 8114119 R 1246995 CDS YP_008738739.1 556570314 17448102 8115147..8115716 1 NC_022657.1 COG1309 Transcriptional regulator; TetR-type regulator 8115716 17448102 AFR_37160 Actinoplanes friuliensis DSM 7358 TetR-type regulator YP_008738739.1 8115147 D 1246995 CDS YP_008738740.1 556570315 17448103 8115784..8117037 1 NC_022657.1 COG5659 FOG: Transposase; putative transposase 8117037 17448103 AFR_37165 Actinoplanes friuliensis DSM 7358 putative transposase YP_008738740.1 8115784 D 1246995 CDS YP_008738741.1 556570316 17448104 complement(8117276..8118949) 1 NC_022657.1 COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit; putative isobutyryl-CoA mutase chain A 8118949 17448104 AFR_37170 Actinoplanes friuliensis DSM 7358 putative isobutyryl-CoA mutase chain A YP_008738741.1 8117276 R 1246995 CDS YP_008738742.1 556570317 17448105 8119095..8120639 1 NC_022657.1 COG3227 Zinc metalloprotease (elastase); thermolysin 8120639 17448105 AFR_37175 Actinoplanes friuliensis DSM 7358 thermolysin YP_008738742.1 8119095 D 1246995 CDS YP_008738743.1 556570318 17448106 8120695..8121297 1 NC_022657.1 hypothetical protein 8121297 17448106 AFR_37180 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738743.1 8120695 D 1246995 CDS YP_008738744.1 556570319 17448107 complement(8121290..8122402) 1 NC_022657.1 COG4213 ABC-type xylose transport system, periplasmic component; putative ABC transporter substrate-binding protein 8122402 17448107 AFR_37185 Actinoplanes friuliensis DSM 7358 putative ABC transporter substrate-binding protein YP_008738744.1 8121290 R 1246995 CDS YP_008738745.1 556570320 17448108 complement(8122497..8124014) 1 NC_022657.1 COG2199 FOG: GGDEF domain; hypothetical protein 8124014 17448108 AFR_37190 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738745.1 8122497 R 1246995 CDS YP_008738746.1 556570321 17448109 complement(8124101..8125264) 1 NC_022657.1 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases; putative monooxygenase 8125264 17448109 AFR_37195 Actinoplanes friuliensis DSM 7358 putative monooxygenase YP_008738746.1 8124101 R 1246995 CDS YP_008738747.1 556570322 17448110 8125328..8125924 1 NC_022657.1 COG1695 Predicted transcriptional regulators; Negative transcription regulator padR 8125924 17448110 AFR_37200 Actinoplanes friuliensis DSM 7358 Negative transcription regulator padR YP_008738747.1 8125328 D 1246995 CDS YP_008738748.1 556570323 17448111 complement(8125921..8126871) 1 NC_022657.1 COG1703 Putative periplasmic protein kinase ArgK and related GTPases of G3E family; LAO/AO transport system kinase 8126871 17448111 AFR_37205 Actinoplanes friuliensis DSM 7358 LAO/AO transport system kinase YP_008738748.1 8125921 R 1246995 CDS YP_008738749.1 556570324 17448112 complement(8126892..8128076) 1 NC_022657.1 COG0183 Acetyl-CoA acetyltransferase; acyltransferase 8128076 17448112 AFR_37210 Actinoplanes friuliensis DSM 7358 acyltransferase YP_008738749.1 8126892 R 1246995 CDS YP_008738750.1 556570325 17448113 8128178..8128630 1 NC_022657.1 COG0346 Lactoylglutathione lyase and related lyases; putative glyoxalase/bleomycin resistance protein/dioxygenase 8128630 17448113 AFR_37215 Actinoplanes friuliensis DSM 7358 putative glyoxalase/bleomycin resistance protein/dioxygenase YP_008738750.1 8128178 D 1246995 CDS YP_008738751.1 556570326 17448114 8128911..8130209 1 NC_022657.1 COG1492 Cobyric acid synthase; Laminin subunit alpha-3 8130209 17448114 AFR_37220 Actinoplanes friuliensis DSM 7358 Laminin subunit alpha-3 YP_008738751.1 8128911 D 1246995 CDS YP_008738752.1 556570327 17448115 8130441..8131991 1 NC_022657.1 hypothetical protein 8131991 17448115 AFR_37225 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738752.1 8130441 D 1246995 CDS YP_008738753.1 556570328 17448116 8132112..8133272 1 NC_022657.1 COG0628 Predicted permease; hypothetical protein 8133272 17448116 AFR_37230 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738753.1 8132112 D 1246995 CDS YP_008738754.1 556570329 17448117 complement(8133276..8134076) 1 NC_022657.1 COG2945 Predicted hydrolase of the alpha/beta superfamily; hypothetical protein 8134076 17448117 AFR_37235 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738754.1 8133276 R 1246995 CDS YP_008738755.1 556570330 17448118 complement(8134082..8134306) 1 NC_022657.1 hypothetical protein 8134306 17448118 AFR_37240 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738755.1 8134082 R 1246995 CDS YP_008738756.1 556570331 17448119 8134499..8135968 1 NC_022657.1 COG1012 NAD-dependent aldehyde dehydrogenases; putative aldehyde dehydrogenase 8135968 17448119 AFR_37245 Actinoplanes friuliensis DSM 7358 putative aldehyde dehydrogenase YP_008738756.1 8134499 D 1246995 CDS YP_008738757.1 556570332 17448120 8135991..8136638 1 NC_022657.1 COG1126 ABC-type polar amino acid transport system, ATPase component; putative ABC transporter ATP-binding protein 8136638 17448120 AFR_37250 Actinoplanes friuliensis DSM 7358 putative ABC transporter ATP-binding protein YP_008738757.1 8135991 D 1246995 CDS YP_008738758.1 556570333 17448121 8136635..8138143 1 NC_022657.1 hypothetical protein 8138143 17448121 AFR_37255 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738758.1 8136635 D 1246995 CDS YP_008738759.1 556570334 17448122 complement(8138140..8138799) 1 NC_022657.1 COG1637 Predicted nuclease of the RecB family; hypothetical protein 8138799 17448122 AFR_37260 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738759.1 8138140 R 1246995 CDS YP_008738760.1 556570335 17448123 8138858..8139484 1 NC_022657.1 hypothetical protein 8139484 17448123 AFR_37265 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738760.1 8138858 D 1246995 CDS YP_008738761.1 556570336 17448124 8139493..8140848 1 NC_022657.1 hypothetical protein 8140848 17448124 AFR_37270 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738761.1 8139493 D 1246995 CDS YP_008738762.1 556570337 17448125 8140934..8143567 1 NC_022657.1 COG1674 DNA segregation ATPase FtsK/SpoIIIE and related proteins; DNA translocase ftsK 8143567 17448125 AFR_37275 Actinoplanes friuliensis DSM 7358 DNA translocase ftsK YP_008738762.1 8140934 D 1246995 CDS YP_008738763.1 556570338 17448126 8143554..8144291 1 NC_022657.1 hypothetical protein 8144291 17448126 AFR_37280 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738763.1 8143554 D 1246995 CDS YP_008738764.1 556570339 17448127 8144311..8145186 1 NC_022657.1 COG1131 ABC-type multidrug transport system, ATPase component; ABC transporter 8145186 17448127 AFR_37285 Actinoplanes friuliensis DSM 7358 ABC transporter YP_008738764.1 8144311 D 1246995 CDS YP_008738765.1 556570340 17448128 8145183..8145974 1 NC_022657.1 COG0842 ABC-type multidrug transport system, permease component; ABC transporter 8145974 17448128 AFR_37290 Actinoplanes friuliensis DSM 7358 ABC transporter YP_008738765.1 8145183 D 1246995 CDS YP_008738766.1 556570341 17448129 complement(8145983..8146831) 1 NC_022657.1 COG1250 3-hydroxyacyl-CoA dehydrogenase; 3-hydroxybutyryl-CoA dehydrogenase 8146831 17448129 AFR_37295 Actinoplanes friuliensis DSM 7358 3-hydroxybutyryl-CoA dehydrogenase YP_008738766.1 8145983 R 1246995 CDS YP_008738767.1 556570342 17448130 8146952..8147314 1 NC_022657.1 hypothetical protein 8147314 17448130 AFR_37300 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738767.1 8146952 D 1246995 CDS YP_008738768.1 556570343 17448131 8147341..8147967 1 NC_022657.1 COG3506 Uncharacterized conserved protein; hypothetical protein 8147967 17448131 AFR_37305 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738768.1 8147341 D 1246995 CDS YP_008738769.1 556570344 17448132 complement(8147974..8149260) 1 NC_022657.1 COG0766 UDP-N-acetylglucosamine enolpyruvyl transferase; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 8149260 17448132 AFR_37310 Actinoplanes friuliensis DSM 7358 UDP-N-acetylglucosamine 1-carboxyvinyltransferase YP_008738769.1 8147974 R 1246995 CDS YP_008738770.1 556570345 17448133 8149302..8149877 1 NC_022657.1 COG2096 Uncharacterized conserved protein; putative cobalamin adenosyltransferase 8149877 17448133 AFR_37315 Actinoplanes friuliensis DSM 7358 putative cobalamin adenosyltransferase YP_008738770.1 8149302 D 1246995 CDS YP_008738771.1 556570346 17448134 complement(8149871..8150338) 1 NC_022657.1 hypothetical protein 8150338 17448134 AFR_37320 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738771.1 8149871 R 1246995 CDS YP_008738772.1 556570347 17448135 complement(8150347..8150628) 1 NC_022657.1 COG0355 F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit); putative F-type proton-transporting ATPase epsilon chain 8150628 17448135 AFR_37325 Actinoplanes friuliensis DSM 7358 putative F-type proton-transporting ATPase epsilon chain YP_008738772.1 8150347 R 1246995 CDS YP_008738773.1 556570348 17448136 complement(8150726..8151859) 1 NC_022657.1 COG1316 Transcriptional regulator; cell envelope-related transcriptional attenuator 8151859 17448136 AFR_37330 Actinoplanes friuliensis DSM 7358 cell envelope-related transcriptional attenuator YP_008738773.1 8150726 R 1246995 CDS YP_008738774.1 556570349 17448137 complement(8152072..8153514) 1 NC_022657.1 COG0055 F0F1-type ATP synthase, beta subunit; F0F1 ATP synthase subunit beta 8153514 17448137 AFR_37335 Actinoplanes friuliensis DSM 7358 F0F1 ATP synthase subunit beta YP_008738774.1 8152072 R 1246995 CDS YP_008738775.1 556570350 17448138 complement(8153514..8154443) 1 NC_022657.1 COG0224 F0F1-type ATP synthase, gamma subunit; putative F-type proton-transporting ATPase gamma chain 8154443 17448138 AFR_37340 Actinoplanes friuliensis DSM 7358 putative F-type proton-transporting ATPase gamma chain YP_008738775.1 8153514 R 1246995 CDS YP_008738776.1 556570351 17448139 complement(8154447..8156099) 1 NC_022657.1 COG0056 F0F1-type ATP synthase, alpha subunit; F0F1 ATP synthase subunit alpha 8156099 17448139 AFR_37345 Actinoplanes friuliensis DSM 7358 F0F1 ATP synthase subunit alpha YP_008738776.1 8154447 R 1246995 CDS YP_008738777.1 556570352 17448140 complement(8156181..8156999) 1 NC_022657.1 COG0712 F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein); putative F-type proton-transporting ATPase delta chain 8156999 17448140 AFR_37350 Actinoplanes friuliensis DSM 7358 putative F-type proton-transporting ATPase delta chain YP_008738777.1 8156181 R 1246995 CDS YP_008738778.1 556570353 17448141 complement(8156999..8157550) 1 NC_022657.1 COG0711 F0F1-type ATP synthase, subunit b; putative F-type proton-transporting ATPase B chain 8157550 17448141 AFR_37355 Actinoplanes friuliensis DSM 7358 putative F-type proton-transporting ATPase B chain YP_008738778.1 8156999 R 1246995 CDS YP_008738779.1 556570354 17448142 complement(8157581..8157808) 1 NC_022657.1 COG0636 F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K; h+transporting two-sector ATPase c subunit 8157808 17448142 AFR_37360 Actinoplanes friuliensis DSM 7358 h+transporting two-sector ATPase c subunit YP_008738779.1 8157581 R 1246995 CDS YP_008738780.1 556570355 17448143 complement(8157876..8158667) 1 NC_022657.1 COG0356 F0F1-type ATP synthase, subunit a; putative F-type proton-transporting ATPase A chain 8158667 17448143 AFR_37365 Actinoplanes friuliensis DSM 7358 putative F-type proton-transporting ATPase A chain YP_008738780.1 8157876 R 1246995 CDS YP_008738781.1 556570356 17448144 complement(8158683..8158844) 1 NC_022657.1 hypothetical protein 8158844 17448144 AFR_37370 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738781.1 8158683 R 1246995 CDS YP_008738782.1 556570357 17448145 complement(8159126..8159611) 1 NC_022657.1 hypothetical protein 8159611 17448145 AFR_37375 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738782.1 8159126 R 1246995 CDS YP_008738783.1 556570358 17448146 complement(8159608..8160939) 1 NC_022657.1 COG0112 Glycine/serine hydroxymethyltransferase; glycine hydroxymethyltransferase 8160939 17448146 AFR_37380 Actinoplanes friuliensis DSM 7358 glycine hydroxymethyltransferase YP_008738783.1 8159608 R 1246995 CDS YP_008738784.1 556570359 17448147 8160978..8162492 1 NC_022657.1 COG0702 Predicted nucleoside-diphosphate-sugar epimerases; putative oxidoreductase 8162492 17448147 AFR_37385 Actinoplanes friuliensis DSM 7358 putative oxidoreductase YP_008738784.1 8160978 D 1246995 CDS YP_008738785.1 556570360 17448148 complement(8162416..8163378) 1 NC_022657.1 COG0009 Putative translation factor (SUA5); hypothetical protein 8163378 17448148 AFR_37390 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738785.1 8162416 R 1246995 CDS YP_008738786.1 556570361 17448149 complement(8163375..8164004) 1 NC_022657.1 COG0394 Protein-tyrosine-phosphatase; low molecular weight phosphotyrosine protein phosphatase 8164004 17448149 AFR_37395 Actinoplanes friuliensis DSM 7358 low molecular weight phosphotyrosine protein phosphatase YP_008738786.1 8163375 R 1246995 CDS YP_008738787.1 556570362 17448150 complement(8164001..8164648) 1 NC_022657.1 COG0009 Putative translation factor (SUA5); hypothetical protein 8164648 17448150 AFR_37400 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738787.1 8164001 R 1246995 CDS YP_008738788.1 556570363 17448151 complement(8164683..8165501) 1 NC_022657.1 COG2890 Methylase of polypeptide chain release factors; putative methyltransferase 8165501 17448151 AFR_37405 Actinoplanes friuliensis DSM 7358 putative methyltransferase YP_008738788.1 8164683 R 1246995 CDS YP_008738789.1 556570364 17448152 8165657..8167162 1 NC_022657.1 COG2199 FOG: GGDEF domain; diguanylate cyclase 8167162 17448152 AFR_37410 Actinoplanes friuliensis DSM 7358 diguanylate cyclase YP_008738789.1 8165657 D 1246995 CDS YP_008738790.1 556570365 17448153 8167192..8168541 1 NC_022657.1 hypothetical protein 8168541 17448153 AFR_37415 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738790.1 8167192 D 1246995 CDS YP_008738791.1 556570366 17448154 complement(8168525..8169616) 1 NC_022657.1 COG0216 Protein chain release factor A; Peptide chain release factor 1 8169616 17448154 AFR_37420 Actinoplanes friuliensis DSM 7358 Peptide chain release factor 1 YP_008738791.1 8168525 R 1246995 CDS YP_008738792.1 556570367 17448155 complement(8169702..8169926) 1 NC_022657.1 COG0254 Ribosomal protein L31; 50S ribosomal protein L31 8169926 17448155 AFR_37425 Actinoplanes friuliensis DSM 7358 50S ribosomal protein L31 YP_008738792.1 8169702 R 1246995 CDS YP_008738793.1 556570368 17448156 8170146..8171213 1 NC_022657.1 putative RNA ligase 8171213 17448156 AFR_37430 Actinoplanes friuliensis DSM 7358 putative RNA ligase YP_008738793.1 8170146 D 1246995 CDS YP_008738794.1 556570369 17448157 8171217..8172113 1 NC_022657.1 COG4088 Predicted nucleotide kinase; hypothetical protein 8172113 17448157 AFR_37435 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738794.1 8171217 D 1246995 CDS YP_008738795.1 556570370 17448158 8172113..8172745 1 NC_022657.1 hypothetical protein 8172745 17448158 AFR_37440 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738795.1 8172113 D 1246995 CDS YP_008738796.1 556570371 17448159 complement(8172742..8173905) 1 NC_022657.1 COG4362 Nitric oxide synthase, oxygenase domain; nitric-oxide synthase 8173905 17448159 AFR_37445 Actinoplanes friuliensis DSM 7358 nitric-oxide synthase YP_008738796.1 8172742 R 1246995 CDS YP_008738797.1 556570372 17448160 complement(8174040..8176241) 1 NC_022657.1 COG1158 Transcription termination factor; transcription termination factor Rho 8176241 17448160 AFR_37450 Actinoplanes friuliensis DSM 7358 transcription termination factor Rho YP_008738797.1 8174040 R 1246995 CDS YP_008738798.1 556570373 17448161 complement(8176553..8177488) 1 NC_022657.1 COG0083 Homoserine kinase; homoserine kinase 8177488 17448161 AFR_37455 Actinoplanes friuliensis DSM 7358 homoserine kinase YP_008738798.1 8176553 R 1246995 CDS YP_008738799.1 556570374 17448162 complement(8177513..8177875) 1 NC_022657.1 hypothetical protein 8177875 17448162 AFR_37460 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738799.1 8177513 R 1246995 CDS YP_008738800.1 556570375 17448163 complement(8178828..8180171) 1 NC_022657.1 COG0477 Permeases of the major facilitator superfamily; major facilitator transporter 8180171 17448163 AFR_37465 Actinoplanes friuliensis DSM 7358 major facilitator transporter YP_008738800.1 8178828 R 1246995 CDS YP_008738801.1 556570376 17448164 complement(8180246..8183581) 1 NC_022657.1 COG0841 Cation/multidrug efflux pump; putative cation/multidrug efflux protein 8183581 17448164 AFR_37470 Actinoplanes friuliensis DSM 7358 putative cation/multidrug efflux protein YP_008738801.1 8180246 R 1246995 CDS YP_008738802.1 556570377 17448165 8183720..8184202 1 NC_022657.1 COG1846 Transcriptional regulators; putative MarR-family transcriptional regulator 8184202 17448165 AFR_37475 Actinoplanes friuliensis DSM 7358 putative MarR-family transcriptional regulator YP_008738802.1 8183720 D 1246995 CDS YP_008738803.1 556570378 17448166 complement(8184633..8185682) 1 NC_022657.1 COG0498 Threonine synthase; putative threonine synthase 8185682 17448166 AFR_37480 Actinoplanes friuliensis DSM 7358 putative threonine synthase YP_008738803.1 8184633 R 1246995 CDS YP_008738804.1 556570379 17448167 complement(8185761..8187068) 1 NC_022657.1 COG0460 Homoserine dehydrogenase; homoserine dehydrogenase 8187068 17448167 AFR_37485 Actinoplanes friuliensis DSM 7358 homoserine dehydrogenase YP_008738804.1 8185761 R 1246995 CDS YP_008738805.1 556570380 17448168 complement(8187065..8188450) 1 NC_022657.1 COG0019 Diaminopimelate decarboxylase; putative diaminopimelate decarboxylase 8188450 17448168 AFR_37490 Actinoplanes friuliensis DSM 7358 putative diaminopimelate decarboxylase YP_008738805.1 8187065 R 1246995 CDS YP_008738806.1 556570381 17448169 complement(8188453..8190117) 1 NC_022657.1 COG0018 Arginyl-tRNA synthetase; arginyl-tRNA ligase 8190117 argS2 17448169 argS2 Actinoplanes friuliensis DSM 7358 arginyl-tRNA ligase YP_008738806.1 8188453 R 1246995 CDS YP_008738807.1 556570382 17448170 8190220..8191005 1 NC_022657.1 hypothetical protein 8191005 17448170 AFR_37500 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738807.1 8190220 D 1246995 CDS YP_008738808.1 556570383 17448171 8191005..8191670 1 NC_022657.1 COG3544 Uncharacterized protein conserved in bacteria; hypothetical protein 8191670 17448171 AFR_37505 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738808.1 8191005 D 1246995 CDS YP_008738809.1 556570384 17448173 complement(8192160..8192525) 1 NC_022657.1 hypothetical protein 8192525 17448173 AFR_37510 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738809.1 8192160 R 1246995 CDS YP_008738810.1 556570385 17448174 8192650..8193543 1 NC_022657.1 COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases; dehydrogenase 8193543 17448174 AFR_37515 Actinoplanes friuliensis DSM 7358 dehydrogenase YP_008738810.1 8192650 D 1246995 CDS YP_008738811.1 556570386 17448175 complement(8193540..8194106) 1 NC_022657.1 hypothetical protein 8194106 17448175 AFR_37520 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738811.1 8193540 R 1246995 CDS YP_008738812.1 556570387 17448176 8194212..8194883 1 NC_022657.1 COG1024 Enoyl-CoA hydratase/carnithine racemase; hypothetical protein 8194883 17448176 AFR_37525 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738812.1 8194212 D 1246995 CDS YP_008738813.1 556570388 17448177 complement(8194887..8195348) 1 NC_022657.1 hypothetical protein 8195348 17448177 AFR_37530 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738813.1 8194887 R 1246995 CDS YP_008738814.1 556570389 17448178 complement(8195336..8195905) 1 NC_022657.1 COG0113 Delta-aminolevulinic acid dehydratase; hypothetical protein 8195905 17448178 AFR_37535 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738814.1 8195336 R 1246995 CDS YP_008738815.1 556570390 17448179 complement(8195959..8199333) 1 NC_022657.1 COG1572 Uncharacterized conserved protein; hypothetical protein 8199333 17448179 AFR_37540 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738815.1 8195959 R 1246995 CDS YP_008738816.1 556570391 17448180 complement(8199617..8200417) 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); short-chain dehydrogenase/reductase SDR 8200417 17448180 AFR_37545 Actinoplanes friuliensis DSM 7358 short-chain dehydrogenase/reductase SDR YP_008738816.1 8199617 R 1246995 CDS YP_008738817.1 556570392 17448181 8200481..8201257 1 NC_022657.1 COG1396 Predicted transcriptional regulators; XRE family transcriptional regulator 8201257 17448181 AFR_37550 Actinoplanes friuliensis DSM 7358 XRE family transcriptional regulator YP_008738817.1 8200481 D 1246995 CDS YP_008738818.1 556570393 17448182 complement(8201254..8202645) 1 NC_022657.1 COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II; AMP-dependent synthetase and ligase 8202645 17448182 AFR_37555 Actinoplanes friuliensis DSM 7358 AMP-dependent synthetase and ligase YP_008738818.1 8201254 R 1246995 CDS YP_008738819.1 556570394 17448183 complement(8202635..8204179) 1 NC_022657.1 COG2072 Predicted flavoprotein involved in K+ transport; FAD-dependent pyridine nucleotide-disulfide oxidoreductase 8204179 17448183 AFR_37560 Actinoplanes friuliensis DSM 7358 FAD-dependent pyridine nucleotide-disulfide oxidoreductase YP_008738819.1 8202635 R 1246995 CDS YP_008738820.1 556570395 17448184 8204243..8205724 1 NC_022657.1 COG2986 Histidine ammonia-lyase; Histidine ammonia-lyase 8205724 17448184 AFR_37565 Actinoplanes friuliensis DSM 7358 Histidine ammonia-lyase YP_008738820.1 8204243 D 1246995 CDS YP_008738821.1 556570396 17448185 8205748..8207313 1 NC_022657.1 COG2072 Predicted flavoprotein involved in K+ transport; FAD dependent oxidoreductase 8207313 17448185 AFR_37570 Actinoplanes friuliensis DSM 7358 FAD dependent oxidoreductase YP_008738821.1 8205748 D 1246995 CDS YP_008738822.1 556570397 17448186 8207321..8208346 1 NC_022657.1 COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases; FMN-dependent alpha-hydroxy acid dehydrogenase 8208346 17448186 AFR_37575 Actinoplanes friuliensis DSM 7358 FMN-dependent alpha-hydroxy acid dehydrogenase YP_008738822.1 8207321 D 1246995 CDS YP_008738823.1 556570398 17448187 8208343..8209680 1 NC_022657.1 COG2124 Cytochrome P450; cytochrome P450-like protein 8209680 17448187 AFR_37580 Actinoplanes friuliensis DSM 7358 cytochrome P450-like protein YP_008738823.1 8208343 D 1246995 CDS YP_008738824.1 556570399 17448188 8209677..8210930 1 NC_022657.1 COG0475 Kef-type K+ transport systems, membrane components; sodium/hydrogen exchanger 8210930 17448188 AFR_37585 Actinoplanes friuliensis DSM 7358 sodium/hydrogen exchanger YP_008738824.1 8209677 D 1246995 CDS YP_008738825.1 556570400 17448189 8211004..8211648 1 NC_022657.1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; winged helix family two component transcriptional regulator 8211648 17448189 AFR_37590 Actinoplanes friuliensis DSM 7358 winged helix family two component transcriptional regulator YP_008738825.1 8211004 D 1246995 CDS YP_008738826.1 556570401 17448190 8211648..8212901 1 NC_022657.1 COG0642 Signal transduction histidine kinase; integral membrane sensor signal transduction histidine kinase 8212901 17448190 AFR_37595 Actinoplanes friuliensis DSM 7358 integral membrane sensor signal transduction histidine kinase YP_008738826.1 8211648 D 1246995 CDS YP_008738827.1 556570402 17448191 8212894..8213208 1 NC_022657.1 hypothetical protein 8213208 17448191 AFR_37600 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738827.1 8212894 D 1246995 CDS YP_008738828.1 556570403 17448192 complement(8213212..8214666) 1 NC_022657.1 COG0515 Serine/threonine protein kinase; putative serine/threonine protein kinase 8214666 17448192 AFR_37605 Actinoplanes friuliensis DSM 7358 putative serine/threonine protein kinase YP_008738828.1 8213212 R 1246995 CDS YP_008738829.1 556570404 17448193 complement(8214837..8215202) 1 NC_022657.1 hypothetical protein 8215202 17448193 AFR_37610 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738829.1 8214837 R 1246995 CDS YP_008738830.1 556570405 17448194 complement(8215246..8216385) 1 NC_022657.1 COG1680 Beta-lactamase class C and other penicillin binding proteins; putative beta-lactamase 8216385 17448194 AFR_37615 Actinoplanes friuliensis DSM 7358 putative beta-lactamase YP_008738830.1 8215246 R 1246995 CDS YP_008738831.1 556570406 17448195 8216515..8216982 1 NC_022657.1 hypothetical protein 8216982 17448195 AFR_37620 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738831.1 8216515 D 1246995 CDS YP_008738832.1 556570407 17448196 8217064..8217510 1 NC_022657.1 hypothetical protein 8217510 17448196 AFR_37625 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738832.1 8217064 D 1246995 CDS YP_008738833.1 556570408 17448197 8217513..8217797 1 NC_022657.1 hypothetical protein 8217797 17448197 AFR_37630 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738833.1 8217513 D 1246995 CDS YP_008738834.1 556570409 17448198 8219642..8219986 1 NC_022657.1 glyoxalase/bleomycin resistance protein/dioxygenase 8219986 17448198 AFR_37635 Actinoplanes friuliensis DSM 7358 glyoxalase/bleomycin resistance protein/dioxygenase YP_008738834.1 8219642 D 1246995 CDS YP_008738835.1 556570410 17448199 8220050..8220676 1 NC_022657.1 COG2085 Predicted dinucleotide-binding enzymes; NADP oxidoreductase coenzyme F420-dependent 8220676 17448199 AFR_37640 Actinoplanes friuliensis DSM 7358 NADP oxidoreductase coenzyme F420-dependent YP_008738835.1 8220050 D 1246995 CDS YP_008738836.1 556570411 17448200 complement(8220663..8220989) 1 NC_022657.1 COG1733 Predicted transcriptional regulators; ydeP-like transcriptional regulator 8220989 17448200 AFR_37645 Actinoplanes friuliensis DSM 7358 ydeP-like transcriptional regulator YP_008738836.1 8220663 R 1246995 CDS YP_008738837.1 556570412 17448201 8221067..8221969 1 NC_022657.1 COG1073 Hydrolases of the alpha/beta superfamily; hypothetical protein 8221969 17448201 AFR_37650 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738837.1 8221067 D 1246995 CDS YP_008738838.1 556570413 17448202 complement(8221884..8222348) 1 NC_022657.1 hypothetical protein 8222348 17448202 AFR_37655 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738838.1 8221884 R 1246995 CDS YP_008738839.1 556570414 17448203 complement(8222362..8223207) 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); short-chain dehydrogenase/reductase SDR 8223207 17448203 AFR_37660 Actinoplanes friuliensis DSM 7358 short-chain dehydrogenase/reductase SDR YP_008738839.1 8222362 R 1246995 CDS YP_008738840.1 556570415 17448204 8223318..8224181 1 NC_022657.1 COG0583 Transcriptional regulator; LysR family transcriptional regulator 8224181 17448204 AFR_37665 Actinoplanes friuliensis DSM 7358 LysR family transcriptional regulator YP_008738840.1 8223318 D 1246995 CDS YP_008738841.1 556570416 17448205 8224244..8224870 1 NC_022657.1 COG1309 Transcriptional regulator; putative TetR-family transcriptional regulator 8224870 17448205 AFR_37670 Actinoplanes friuliensis DSM 7358 putative TetR-family transcriptional regulator YP_008738841.1 8224244 D 1246995 CDS YP_008738842.1 556570417 17448206 8224870..8226543 1 NC_022657.1 COG0477 Permeases of the major facilitator superfamily; putative MFS transporter 8226543 17448206 AFR_37675 Actinoplanes friuliensis DSM 7358 putative MFS transporter YP_008738842.1 8224870 D 1246995 CDS YP_008738843.1 556570418 17448207 complement(8227312..8227647) 1 NC_022657.1 COG1742 Uncharacterized conserved protein; hypothetical protein 8227647 17448207 AFR_37680 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738843.1 8227312 R 1246995 CDS YP_008738844.1 556570419 17448208 complement(8227673..8228029) 1 NC_022657.1 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); hypothetical protein 8228029 17448208 AFR_37685 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738844.1 8227673 R 1246995 CDS YP_008738845.1 556570420 17448209 8228307..8229311 1 NC_022657.1 COG2207 AraC-type DNA-binding domain-containing proteins; putative AraC-family transcriptional regulator 8229311 17448209 AFR_37690 Actinoplanes friuliensis DSM 7358 putative AraC-family transcriptional regulator YP_008738845.1 8228307 D 1246995 CDS YP_008738846.1 556570421 17448210 complement(8229377..8229715) 1 NC_022657.1 hypothetical protein 8229715 17448210 AFR_37695 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738846.1 8229377 R 1246995 CDS YP_008738847.1 556570422 17448211 8230033..8230323 1 NC_022657.1 hypothetical protein 8230323 17448211 AFR_37700 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738847.1 8230033 D 1246995 CDS YP_008738848.1 556570423 17448212 complement(8230328..8230804) 1 NC_022657.1 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; N-acetyltransferase GCN5 8230804 17448212 AFR_37705 Actinoplanes friuliensis DSM 7358 N-acetyltransferase GCN5 YP_008738848.1 8230328 R 1246995 CDS YP_008738849.1 556570424 17448213 8230857..8231417 1 NC_022657.1 COG1309 Transcriptional regulator; putative TetR-family transcriptional regulator 8231417 17448213 AFR_37710 Actinoplanes friuliensis DSM 7358 putative TetR-family transcriptional regulator YP_008738849.1 8230857 D 1246995 CDS YP_008738850.1 556570425 17448214 complement(8231398..8232897) 1 NC_022657.1 COG2041 Sulfite oxidase and related enzymes; putative membrane-bound oxidoreductase 8232897 17448214 AFR_37715 Actinoplanes friuliensis DSM 7358 putative membrane-bound oxidoreductase YP_008738850.1 8231398 R 1246995 CDS YP_008738851.1 556570426 17448215 complement(8232980..8233612) 1 NC_022657.1 COG2335 Secreted and surface protein containing fasciclin-like repeats; hypothetical protein 8233612 17448215 AFR_37720 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738851.1 8232980 R 1246995 CDS YP_008738852.1 556570427 17448216 complement(8233720..8234094) 1 NC_022657.1 hypothetical protein 8234094 17448216 AFR_37725 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738852.1 8233720 R 1246995 CDS YP_008738853.1 556570428 17448217 complement(8234164..8234919) 1 NC_022657.1 hypothetical protein 8234919 17448217 AFR_37730 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738853.1 8234164 R 1246995 CDS YP_008738854.1 556570429 17448218 complement(8234919..8235539) 1 NC_022657.1 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; RNA polymerase sigma factor sigK 8235539 17448218 AFR_37735 Actinoplanes friuliensis DSM 7358 RNA polymerase sigma factor sigK YP_008738854.1 8234919 R 1246995 CDS YP_008738855.1 556570430 17448219 8235667..8236182 1 NC_022657.1 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; putative RNA polymerase ECF-subfamily sigma factor 8236182 17448219 AFR_37740 Actinoplanes friuliensis DSM 7358 putative RNA polymerase ECF-subfamily sigma factor YP_008738855.1 8235667 D 1246995 CDS YP_008738856.1 556570431 17448220 8236179..8237402 1 NC_022657.1 hypothetical protein 8237402 17448220 AFR_37745 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738856.1 8236179 D 1246995 CDS YP_008738857.1 556570432 17448221 complement(8237399..8238295) 1 NC_022657.1 COG0673 Predicted dehydrogenases and related proteins; Inositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase 8238295 17448221 AFR_37750 Actinoplanes friuliensis DSM 7358 Inositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase YP_008738857.1 8237399 R 1246995 CDS YP_008738858.1 556570433 17448222 8238365..8238739 1 NC_022657.1 hypothetical protein 8238739 17448222 AFR_37755 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738858.1 8238365 D 1246995 CDS YP_008738859.1 556570434 17448223 8238732..8239160 1 NC_022657.1 hypothetical protein 8239160 17448223 AFR_37760 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738859.1 8238732 D 1246995 CDS YP_008738860.1 556570435 17448224 complement(8239157..8240137) 1 NC_022657.1 hypothetical protein 8240137 17448224 AFR_37765 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738860.1 8239157 R 1246995 CDS YP_008738861.1 556570436 17448225 complement(8240149..8240646) 1 NC_022657.1 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; RNA polymerase sigma factor, sigma-70 family/RNA polymerase sigma-70 factor, sigma-E family protein 8240646 17448225 AFR_37770 Actinoplanes friuliensis DSM 7358 RNA polymerase sigma factor, sigma-70 family/RNA polymerase sigma-70 factor, sigma-E family protein YP_008738861.1 8240149 R 1246995 CDS YP_008738862.1 556570437 17448226 complement(8240688..8242151) 1 NC_022657.1 COG0754 Glutathionylspermidine synthase; putative glutathionylspermidine synthase 8242151 17448226 AFR_37775 Actinoplanes friuliensis DSM 7358 putative glutathionylspermidine synthase YP_008738862.1 8240688 R 1246995 CDS YP_008738863.1 556570438 17448227 complement(8242155..8242541) 1 NC_022657.1 hypothetical protein 8242541 17448227 AFR_37780 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738863.1 8242155 R 1246995 CDS YP_008738864.1 556570439 17448228 complement(8242640..8243398) 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); 3-oxoacyl-ACP reductase 8243398 17448228 AFR_37785 Actinoplanes friuliensis DSM 7358 3-oxoacyl-ACP reductase YP_008738864.1 8242640 R 1246995 CDS YP_008738865.1 556570440 17448229 complement(8243533..8245179) 1 NC_022657.1 COG0366 Glycosidases; putative glycosyl hydrolase 8245179 17448229 AFR_37790 Actinoplanes friuliensis DSM 7358 putative glycosyl hydrolase YP_008738865.1 8243533 R 1246995 CDS YP_008738866.1 556570441 17448230 complement(8245160..8246020) 1 NC_022657.1 COG3768 Predicted membrane protein; hypothetical protein 8246020 17448230 AFR_37795 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738866.1 8245160 R 1246995 CDS YP_008738867.1 556570442 17448231 complement(8246017..8246454) 1 NC_022657.1 hypothetical protein 8246454 17448231 AFR_37800 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738867.1 8246017 R 1246995 CDS YP_008738868.1 556570443 17448232 complement(8246519..8247559) 1 NC_022657.1 hypothetical protein 8247559 17448232 AFR_37805 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738868.1 8246519 R 1246995 CDS YP_008738869.1 556570444 17448233 complement(8247624..8247968) 1 NC_022657.1 COG1695 Predicted transcriptional regulators; PadR-like family transcriptional regulator 8247968 17448233 AFR_37810 Actinoplanes friuliensis DSM 7358 PadR-like family transcriptional regulator YP_008738869.1 8247624 R 1246995 CDS YP_008738870.1 556570445 17448234 8248063..8248728 1 NC_022657.1 COG0586 Uncharacterized membrane-associated protein; hypothetical protein 8248728 17448234 AFR_37815 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738870.1 8248063 D 1246995 CDS YP_008738871.1 556570446 17448235 complement(8248754..8249962) 1 NC_022657.1 COG3979 Uncharacterized protein contain chitin-binding domain type 3; putative glycosyl hydrolase 8249962 17448235 AFR_37820 Actinoplanes friuliensis DSM 7358 putative glycosyl hydrolase YP_008738871.1 8248754 R 1246995 CDS YP_008738872.1 556570447 17448236 complement(8249994..8251115) 1 NC_022657.1 COG3979 Uncharacterized protein contain chitin-binding domain type 3; putative glycosyl hydrolase 8251115 17448236 AFR_37825 Actinoplanes friuliensis DSM 7358 putative glycosyl hydrolase YP_008738872.1 8249994 R 1246995 CDS YP_008738873.1 556570448 17448237 complement(8251415..8252071) 1 NC_022657.1 COG0706 Preprotein translocase subunit YidC; Inner membrane protein oxaA 8252071 17448237 AFR_37830 Actinoplanes friuliensis DSM 7358 Inner membrane protein oxaA YP_008738873.1 8251415 R 1246995 CDS YP_008738874.1 556570449 17448238 complement(8252123..8252425) 1 NC_022657.1 hypothetical protein 8252425 17448238 AFR_37835 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738874.1 8252123 R 1246995 CDS YP_008738875.1 556570450 17448239 8252541..8253659 1 NC_022657.1 COG2170 Uncharacterized conserved protein; carboxylate-amine ligase 8253659 17448239 AFR_37840 Actinoplanes friuliensis DSM 7358 carboxylate-amine ligase YP_008738875.1 8252541 D 1246995 CDS YP_008738876.1 556570451 17448240 8253656..8255035 1 NC_022657.1 COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases; fad-dependent pyridine nucleotide-disulfide oxidoreductase 8255035 17448240 AFR_37845 Actinoplanes friuliensis DSM 7358 fad-dependent pyridine nucleotide-disulfide oxidoreductase YP_008738876.1 8253656 D 1246995 CDS YP_008738877.1 556570452 17448241 8255288..8256628 1 NC_022657.1 COG0726 Predicted xylanase/chitin deacetylase; polysaccharide deacetylase 8256628 17448241 AFR_37850 Actinoplanes friuliensis DSM 7358 polysaccharide deacetylase YP_008738877.1 8255288 D 1246995 CDS YP_008738878.1 556570453 17448242 complement(8256614..8257405) 1 NC_022657.1 COG0266 Formamidopyrimidine-DNA glycosylase; endonuclease VIII 8257405 17448242 AFR_37855 Actinoplanes friuliensis DSM 7358 endonuclease VIII YP_008738878.1 8256614 R 1246995 CDS YP_008738879.1 556570454 17448243 8257563..8258171 1 NC_022657.1 COG0740 Protease subunit of ATP-dependent Clp proteases; ATP-dependent Clp protease, protease subunit 8258171 17448243 AFR_37860 Actinoplanes friuliensis DSM 7358 ATP-dependent Clp protease, protease subunit YP_008738879.1 8257563 D 1246995 CDS YP_008738880.1 556570455 17448244 8258277..8258948 1 NC_022657.1 hypothetical protein 8258948 17448244 AFR_37865 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738880.1 8258277 D 1246995 CDS YP_008738881.1 556570456 17448245 8259197..8260003 1 NC_022657.1 COG1834 N-Dimethylarginine dimethylaminohydrolase; putative amidinotransferase 8260003 17448245 AFR_37870 Actinoplanes friuliensis DSM 7358 putative amidinotransferase YP_008738881.1 8259197 D 1246995 CDS YP_008738882.1 556570457 17448246 8260000..8261211 1 NC_022657.1 COG4992 Ornithine/acetylornithine aminotransferase; putative ornithine aminotransferase 8261211 17448246 AFR_37875 Actinoplanes friuliensis DSM 7358 putative ornithine aminotransferase YP_008738882.1 8260000 D 1246995 CDS YP_008738883.1 556570458 17448247 complement(8261208..8262353) 1 NC_022657.1 hypothetical protein 8262353 17448247 AFR_37880 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738883.1 8261208 R 1246995 CDS YP_008738884.1 556570459 17448248 complement(8262433..8262726) 1 NC_022657.1 COG2154 Pterin-4a-carbinolamine dehydratase; transcriptional coactivator/pterin dehydratase 8262726 17448248 AFR_37885 Actinoplanes friuliensis DSM 7358 transcriptional coactivator/pterin dehydratase YP_008738884.1 8262433 R 1246995 CDS YP_008738885.1 556570460 17448249 8262840..8263619 1 NC_022657.1 Putative lipoprotein 8263619 17448249 AFR_37890 Actinoplanes friuliensis DSM 7358 Putative lipoprotein YP_008738885.1 8262840 D 1246995 CDS YP_008738886.1 556570461 17448250 8263719..8264528 1 NC_022657.1 hypothetical protein 8264528 17448250 AFR_37895 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738886.1 8263719 D 1246995 CDS YP_008738887.1 556570462 17448251 complement(8264562..8265617) 1 NC_022657.1 putative phospholipid/glycerol acyltransferase 8265617 17448251 AFR_37900 Actinoplanes friuliensis DSM 7358 putative phospholipid/glycerol acyltransferase YP_008738887.1 8264562 R 1246995 CDS YP_008738888.1 556570463 17448252 complement(8265617..8266441) 1 NC_022657.1 COG1752 Predicted esterase of the alpha-beta hydrolase superfamily; putative Patatin-like phospholipase 8266441 17448252 AFR_37905 Actinoplanes friuliensis DSM 7358 putative Patatin-like phospholipase YP_008738888.1 8265617 R 1246995 CDS YP_008738889.1 556570464 17448253 complement(8267153..8268547) 1 NC_022657.1 COG3979 Uncharacterized protein contain chitin-binding domain type 3; putative glycosyl hydrolase 8268547 17448253 AFR_37910 Actinoplanes friuliensis DSM 7358 putative glycosyl hydrolase YP_008738889.1 8267153 R 1246995 CDS YP_008738890.1 556570465 17448254 complement(8268628..8269833) 1 NC_022657.1 COG3839 ABC-type sugar transport systems, ATPase components; ABC transporter-like protein 8269833 17448254 AFR_37915 Actinoplanes friuliensis DSM 7358 ABC transporter-like protein YP_008738890.1 8268628 R 1246995 CDS YP_008738891.1 556570466 17448255 complement(8269884..8270759) 1 NC_022657.1 hypothetical protein 8270759 17448255 AFR_37920 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738891.1 8269884 R 1246995 CDS YP_008738892.1 556570467 17448256 complement(8270809..8271024) 1 NC_022657.1 hypothetical protein 8271024 17448256 AFR_37925 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738892.1 8270809 R 1246995 CDS YP_008738893.1 556570468 17448257 complement(8271028..8274180) 1 NC_022657.1 COG1994 Zn-dependent proteases; cyclic nucleotide-binding protein 8274180 17448257 AFR_37930 Actinoplanes friuliensis DSM 7358 cyclic nucleotide-binding protein YP_008738893.1 8271028 R 1246995 CDS YP_008738894.1 556570469 17448258 complement(8274389..8275456) 1 NC_022657.1 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain; PepD-like putative serine protease 8275456 17448258 AFR_37935 Actinoplanes friuliensis DSM 7358 PepD-like putative serine protease YP_008738894.1 8274389 R 1246995 CDS YP_008738895.1 556570470 17448259 complement(8276096..8277658) 1 NC_022657.1 COG0642 Signal transduction histidine kinase; putative two-component system sensor kinase 8277658 17448259 AFR_37940 Actinoplanes friuliensis DSM 7358 putative two-component system sensor kinase YP_008738895.1 8276096 R 1246995 CDS YP_008738896.1 556570471 17448260 complement(8277666..8278382) 1 NC_022657.1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; putative two-component system response regulator 8278382 17448260 AFR_37945 Actinoplanes friuliensis DSM 7358 putative two-component system response regulator YP_008738896.1 8277666 R 1246995 CDS YP_008738897.1 556570472 17448261 complement(8278450..8279226) 1 NC_022657.1 COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase; putative acyltransferase 8279226 17448261 AFR_37950 Actinoplanes friuliensis DSM 7358 putative acyltransferase YP_008738897.1 8278450 R 1246995 CDS YP_008738898.1 556570473 17448262 complement(8279223..8279969) 1 NC_022657.1 COG3176 Putative hemolysin; hypothetical protein 8279969 17448262 AFR_37955 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738898.1 8279223 R 1246995 CDS YP_008738899.1 556570474 17448263 8280139..8281056 1 NC_022657.1 COG1131 ABC-type multidrug transport system, ATPase component; ABC transporter 8281056 17448263 AFR_37960 Actinoplanes friuliensis DSM 7358 ABC transporter YP_008738899.1 8280139 D 1246995 CDS YP_008738900.1 556570475 17448264 8281053..8281883 1 NC_022657.1 hypothetical protein 8281883 17448264 AFR_37965 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738900.1 8281053 D 1246995 CDS YP_008738901.1 556570476 17448265 8282042..8285785 1 NC_022657.1 COG0567 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes; alpha-ketoglutarate decarboxylase 8285785 kgd 17448265 kgd Actinoplanes friuliensis DSM 7358 alpha-ketoglutarate decarboxylase YP_008738901.1 8282042 D 1246995 CDS YP_008738902.1 556570477 17448266 8285856..8286035 1 NC_022657.1 hypothetical protein 8286035 17448266 AFR_37975 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738902.1 8285856 D 1246995 CDS YP_008738903.1 556570478 17448267 8286036..8286785 1 NC_022657.1 COG3910 Predicted ATPase; ATPase AAA 8286785 17448267 AFR_37980 Actinoplanes friuliensis DSM 7358 ATPase AAA YP_008738903.1 8286036 D 1246995 CDS YP_008738904.1 556570479 17448268 complement(8286794..8288581) 1 NC_022657.1 COG5265 ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components; ABC transporter ATPase/permease 8288581 17448268 AFR_37985 Actinoplanes friuliensis DSM 7358 ABC transporter ATPase/permease YP_008738904.1 8286794 R 1246995 CDS YP_008738905.1 556570480 17448269 complement(8288749..8290710) 1 NC_022657.1 COG1132 ABC-type multidrug transport system, ATPase and permease components; multidrug ABC transporter ATPase/permease 8290710 17448269 AFR_37990 Actinoplanes friuliensis DSM 7358 multidrug ABC transporter ATPase/permease YP_008738905.1 8288749 R 1246995 CDS YP_008738906.1 556570481 17448270 8290823..8292889 1 NC_022657.1 COG0857 BioD-like N-terminal domain of phosphotransacetylase; phosphate acetyltransferase 8292889 17448270 AFR_37995 Actinoplanes friuliensis DSM 7358 phosphate acetyltransferase YP_008738906.1 8290823 D 1246995 CDS YP_008738907.1 556570482 17448271 8292886..8293986 1 NC_022657.1 COG0282 Acetate kinase; putative acetate kinase 8293986 17448271 AFR_38000 Actinoplanes friuliensis DSM 7358 putative acetate kinase YP_008738907.1 8292886 D 1246995 CDS YP_008738908.1 556570483 17448272 complement(8294645..8294824) 1 NC_022657.1 hypothetical protein 8294824 17448272 AFR_38005 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738908.1 8294645 R 1246995 CDS YP_008738909.1 556570484 17448273 8295441..8296352 1 NC_022657.1 COG0412 Dienelactone hydrolase and related enzymes; chlorophyllase-like protein 8296352 17448273 AFR_38010 Actinoplanes friuliensis DSM 7358 chlorophyllase-like protein YP_008738909.1 8295441 D 1246995 CDS YP_008738910.1 556570485 17448274 complement(8296349..8297248) 1 NC_022657.1 COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases; putative alcohol dehydrogenase 8297248 17448274 AFR_38015 Actinoplanes friuliensis DSM 7358 putative alcohol dehydrogenase YP_008738910.1 8296349 R 1246995 CDS YP_008738911.1 556570486 17448275 complement(8297370..8298629) 1 NC_022657.1 COG0281 Malic enzyme; putative malate dehydrogenase 8298629 17448275 AFR_38020 Actinoplanes friuliensis DSM 7358 putative malate dehydrogenase YP_008738911.1 8297370 R 1246995 CDS YP_008738912.1 556570487 17448276 complement(8298768..8299064) 1 NC_022657.1 COG0681 Signal peptidase I; putative signal peptidase 8299064 17448276 AFR_38025 Actinoplanes friuliensis DSM 7358 putative signal peptidase YP_008738912.1 8298768 R 1246995 CDS YP_008738913.1 556570488 17448277 8299161..8299565 1 NC_022657.1 superoxide dismutase, Ni 8299565 17448277 AFR_38030 Actinoplanes friuliensis DSM 7358 superoxide dismutase, Ni YP_008738913.1 8299161 D 1246995 CDS YP_008738914.1 556570489 17448278 8299562..8300062 1 NC_022657.1 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; GCN5-like N-acetyltransferase 8300062 17448278 AFR_38035 Actinoplanes friuliensis DSM 7358 GCN5-like N-acetyltransferase YP_008738914.1 8299562 D 1246995 CDS YP_008738915.1 556570490 17448279 8300091..8300504 1 NC_022657.1 COG2172 Anti-sigma regulatory factor (Ser/Thr protein kinase); putative anti-sigma regulatory factor 8300504 17448279 AFR_38040 Actinoplanes friuliensis DSM 7358 putative anti-sigma regulatory factor YP_008738915.1 8300091 D 1246995 CDS YP_008738916.1 556570491 17448280 complement(8300512..8301207) 1 NC_022657.1 COG2186 Transcriptional regulators; Uxu operon regulator 8301207 17448280 AFR_38045 Actinoplanes friuliensis DSM 7358 Uxu operon regulator YP_008738916.1 8300512 R 1246995 CDS YP_008738917.1 556570492 17448281 complement(8301272..8301661) 1 NC_022657.1 hypothetical protein 8301661 17448281 AFR_38050 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738917.1 8301272 R 1246995 CDS YP_008738918.1 556570493 17448282 8301775..8302665 1 NC_022657.1 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase; putative lipid kinase yegS-like protein 8302665 17448282 AFR_38055 Actinoplanes friuliensis DSM 7358 putative lipid kinase yegS-like protein YP_008738918.1 8301775 D 1246995 CDS YP_008738919.1 556570494 17448283 8303091..8303345 1 NC_022657.1 transcription factor WhiB 8303345 17448283 AFR_38060 Actinoplanes friuliensis DSM 7358 transcription factor WhiB YP_008738919.1 8303091 D 1246995 CDS YP_008738920.1 556570495 17448284 complement(8304137..8304913) 1 NC_022657.1 COG2138 Uncharacterized conserved protein; cobalamin (vitamin B12) biosynthesis CbiX protein 8304913 17448284 AFR_38065 Actinoplanes friuliensis DSM 7358 cobalamin (vitamin B12) biosynthesis CbiX protein YP_008738920.1 8304137 R 1246995 CDS YP_008738921.1 556570496 17448285 complement(8304895..8305659) 1 NC_022657.1 COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes; phosphoadenosine phosphosulfate reductase 8305659 17448285 AFR_38070 Actinoplanes friuliensis DSM 7358 phosphoadenosine phosphosulfate reductase YP_008738921.1 8304895 R 1246995 CDS YP_008738922.1 556570497 17448286 complement(8305656..8305814) 1 NC_022657.1 hypothetical protein 8305814 17448286 AFR_38075 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738922.1 8305656 R 1246995 CDS YP_008738923.1 556570498 17448287 complement(8305811..8307505) 1 NC_022657.1 COG0155 Sulfite reductase, beta subunit (hemoprotein); putative nitrite/sulfite reductase 8307505 17448287 AFR_38080 Actinoplanes friuliensis DSM 7358 putative nitrite/sulfite reductase YP_008738923.1 8305811 R 1246995 CDS YP_008738924.1 556570499 17448288 8307927..8309399 1 NC_022657.1 COG5305 Predicted membrane protein; hypothetical protein 8309399 17448288 AFR_38085 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738924.1 8307927 D 1246995 CDS YP_008738925.1 556570500 17448289 complement(8309396..8310088) 1 NC_022657.1 hypothetical protein 8310088 17448289 AFR_38090 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738925.1 8309396 R 1246995 CDS YP_008738926.1 556570501 17448290 complement(8310109..8311656) 1 NC_022657.1 COG3920 Signal transduction histidine kinase; Signal transduction histidine kinase 8311656 17448290 AFR_38095 Actinoplanes friuliensis DSM 7358 Signal transduction histidine kinase YP_008738926.1 8310109 R 1246995 CDS YP_008738927.1 556570502 17448291 complement(8311696..8312730) 1 NC_022657.1 COG0449 Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains; putative phosphosugar isomerase 8312730 17448291 AFR_38100 Actinoplanes friuliensis DSM 7358 putative phosphosugar isomerase YP_008738927.1 8311696 R 1246995 CDS YP_008738928.1 556570503 17448292 8312927..8314555 1 NC_022657.1 COG0457 FOG: TPR repeat; Pentatricopeptide repeat-containing protein 8314555 17448292 AFR_38105 Actinoplanes friuliensis DSM 7358 Pentatricopeptide repeat-containing protein YP_008738928.1 8312927 D 1246995 CDS YP_008738929.1 556570504 17448293 complement(8314545..8314760) 1 NC_022657.1 COG0511 Biotin carboxyl carrier protein; biotin/lipoyl attachment domain-containing protein 8314760 17448293 AFR_38110 Actinoplanes friuliensis DSM 7358 biotin/lipoyl attachment domain-containing protein YP_008738929.1 8314545 R 1246995 CDS YP_008738930.1 556570505 17448294 complement(8315045..8315332) 1 NC_022657.1 anti-sigma factor 8315332 17448294 AFR_38115 Actinoplanes friuliensis DSM 7358 anti-sigma factor YP_008738930.1 8315045 R 1246995 CDS YP_008738931.1 556570506 17448295 complement(8315329..8315961) 1 NC_022657.1 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; putative RNA polymerase ECF-subfamily sigma factor 8315961 17448295 AFR_38120 Actinoplanes friuliensis DSM 7358 putative RNA polymerase ECF-subfamily sigma factor YP_008738931.1 8315329 R 1246995 CDS YP_008738932.1 556570507 17448296 complement(8316230..8316832) 1 NC_022657.1 COG3571 Predicted hydrolase of the alpha/beta-hydrolase fold; hypothetical protein 8316832 17448296 AFR_38125 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738932.1 8316230 R 1246995 CDS YP_008738933.1 556570508 17448297 complement(8316844..8316951) 1 NC_022657.1 transcription factor WhiB 8316951 17448297 AFR_38130 Actinoplanes friuliensis DSM 7358 transcription factor WhiB YP_008738933.1 8316844 R 1246995 CDS YP_008738934.1 556570509 17448298 complement(8317469..8318158) 1 NC_022657.1 COG2135 Uncharacterized conserved protein; hypothetical protein 8318158 17448298 AFR_38135 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738934.1 8317469 R 1246995 CDS YP_008738935.1 556570510 17448299 8318237..8319520 1 NC_022657.1 COG0128 5-enolpyruvylshikimate-3-phosphate synthase; 3-phosphoshikimate 1-carboxyvinyltransferase 8319520 17448299 AFR_38140 Actinoplanes friuliensis DSM 7358 3-phosphoshikimate 1-carboxyvinyltransferase YP_008738935.1 8318237 D 1246995 CDS YP_008738936.1 556570511 17448300 8319637..8320575 1 NC_022657.1 COG1162 Predicted GTPases; putative GTPase 8320575 17448300 AFR_38145 Actinoplanes friuliensis DSM 7358 putative GTPase YP_008738936.1 8319637 D 1246995 CDS YP_008738937.1 556570512 17448301 8320628..8321431 1 NC_022657.1 COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family; putative inositol monophosphatase 8321431 17448301 AFR_38150 Actinoplanes friuliensis DSM 7358 putative inositol monophosphatase YP_008738937.1 8320628 D 1246995 CDS YP_008738938.1 556570513 17448302 8321483..8322376 1 NC_022657.1 hypothetical protein 8322376 17448302 AFR_38155 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738938.1 8321483 D 1246995 CDS YP_008738939.1 556570514 17448303 8322518..8323291 1 NC_022657.1 hypothetical protein 8323291 17448303 AFR_38160 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738939.1 8322518 D 1246995 CDS YP_008738940.1 556570515 17448304 8323302..8323862 1 NC_022657.1 hypothetical protein 8323862 17448304 AFR_38165 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738940.1 8323302 D 1246995 CDS YP_008738941.1 556570516 17448305 complement(8323863..8324492) 1 NC_022657.1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; two component LuxR family transcriptional regulator 8324492 17448305 AFR_38170 Actinoplanes friuliensis DSM 7358 two component LuxR family transcriptional regulator YP_008738941.1 8323863 R 1246995 CDS YP_008738942.1 556570517 17448306 complement(8324516..8325652) 1 NC_022657.1 COG4585 Signal transduction histidine kinase; signal transduction histidine kinase 8325652 17448306 AFR_38175 Actinoplanes friuliensis DSM 7358 signal transduction histidine kinase YP_008738942.1 8324516 R 1246995 CDS YP_008738943.1 556570518 17448307 8325640..8326104 1 NC_022657.1 COG2172 Anti-sigma regulatory factor (Ser/Thr protein kinase); ATP-binding protein 8326104 17448307 AFR_38180 Actinoplanes friuliensis DSM 7358 ATP-binding protein YP_008738943.1 8325640 D 1246995 CDS YP_008738944.1 556570519 17448308 8326277..8327281 1 NC_022657.1 COG2273 Beta-glucanase/Beta-glucan synthetase; glycoside hydrolase 8327281 17448308 AFR_38185 Actinoplanes friuliensis DSM 7358 glycoside hydrolase YP_008738944.1 8326277 D 1246995 CDS YP_008738945.1 556570520 17448309 8327393..8328634 1 NC_022657.1 COG2273 Beta-glucanase/Beta-glucan synthetase; putative glycosyl hydrolase 8328634 17448309 AFR_38190 Actinoplanes friuliensis DSM 7358 putative glycosyl hydrolase YP_008738945.1 8327393 D 1246995 CDS YP_008738946.1 556570521 17448310 8328759..8331119 1 NC_022657.1 COG0744 Membrane carboxypeptidase (penicillin-binding protein); putative glycosyltransferase 8331119 17448310 AFR_38195 Actinoplanes friuliensis DSM 7358 putative glycosyltransferase YP_008738946.1 8328759 D 1246995 CDS YP_008738947.1 556570522 17448311 complement(8331116..8332348) 1 NC_022657.1 chitosanase 8332348 17448311 AFR_38200 Actinoplanes friuliensis DSM 7358 chitosanase YP_008738947.1 8331116 R 1246995 CDS YP_008738948.1 556570523 17448312 complement(8332372..8332632) 1 NC_022657.1 hypothetical protein 8332632 17448312 AFR_38205 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738948.1 8332372 R 1246995 CDS YP_008738949.1 556570524 17448313 8332721..8334667 1 NC_022657.1 COG1640 4-alpha-glucanotransferase; putative 4-alpha-glucanotransferase 8334667 17448313 AFR_38210 Actinoplanes friuliensis DSM 7358 putative 4-alpha-glucanotransferase YP_008738949.1 8332721 D 1246995 CDS YP_008738950.1 556570525 17448314 8334664..8334843 1 NC_022657.1 hypothetical protein 8334843 17448314 AFR_38215 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738950.1 8334664 D 1246995 CDS YP_008738951.1 556570526 17448315 8334898..8335077 1 NC_022657.1 hypothetical protein 8335077 17448315 AFR_38220 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738951.1 8334898 D 1246995 CDS YP_008738952.1 556570527 17448316 complement(8335108..8335500) 1 NC_022657.1 hypothetical protein 8335500 17448316 AFR_38225 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738952.1 8335108 R 1246995 CDS YP_008738953.1 556570528 17448317 8335677..8336630 1 NC_022657.1 COG2172 Anti-sigma regulatory factor (Ser/Thr protein kinase); ATP-binding protein 8336630 17448317 AFR_38230 Actinoplanes friuliensis DSM 7358 ATP-binding protein YP_008738953.1 8335677 D 1246995 CDS YP_008738954.1 556570529 17448318 8336738..8339356 1 NC_022657.1 COG3321 Polyketide synthase modules and related proteins; beta keto-acyl synthase 8339356 17448318 AFR_38235 Actinoplanes friuliensis DSM 7358 beta keto-acyl synthase YP_008738954.1 8336738 D 1246995 CDS YP_008738955.1 556570530 17448319 complement(8339319..8340572) 1 NC_022657.1 COG4102 Uncharacterized protein conserved in bacteria; hypothetical protein 8340572 17448319 AFR_38240 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738955.1 8339319 R 1246995 CDS YP_008738956.1 556570531 17448320 complement(8340575..8342074) 1 NC_022657.1 COG5267 Uncharacterized protein conserved in bacteria; hypothetical protein 8342074 17448320 AFR_38245 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738956.1 8340575 R 1246995 CDS YP_008738957.1 556570532 17448321 8342084..8342941 1 NC_022657.1 COG0421 Spermidine synthase; hypothetical protein 8342941 17448321 AFR_38250 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738957.1 8342084 D 1246995 CDS YP_008738958.1 556570533 17448322 8343059..8344651 1 NC_022657.1 translation initiation factor IF-2 8344651 17448322 AFR_38255 Actinoplanes friuliensis DSM 7358 translation initiation factor IF-2 YP_008738958.1 8343059 D 1246995 CDS YP_008738959.1 556570534 17448323 8344740..8346932 1 NC_022657.1 COG2409 Predicted drug exporters of the RND superfamily; MMPL domain-containing protein 8346932 17448323 AFR_38260 Actinoplanes friuliensis DSM 7358 MMPL domain-containing protein YP_008738959.1 8344740 D 1246995 CDS YP_008738960.1 556570535 17448324 complement(8346940..8348145) 1 NC_022657.1 COG0861 Membrane protein TerC, possibly involved in tellurium resistance; putative TerC-family integral membrane protein 8348145 17448324 AFR_38265 Actinoplanes friuliensis DSM 7358 putative TerC-family integral membrane protein YP_008738960.1 8346940 R 1246995 CDS YP_008738961.1 556570536 17448325 8348302..8349057 1 NC_022657.1 hypothetical protein 8349057 17448325 AFR_38270 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738961.1 8348302 D 1246995 CDS YP_008738962.1 556570537 17448326 complement(8349013..8349771) 1 NC_022657.1 COG1357 Uncharacterized low-complexity proteins; pentapeptide repeat-containing protein 8349771 17448326 AFR_38275 Actinoplanes friuliensis DSM 7358 pentapeptide repeat-containing protein YP_008738962.1 8349013 R 1246995 CDS YP_008738963.1 556570538 17448327 8349915..8351012 1 NC_022657.1 hypothetical protein 8351012 17448327 AFR_38280 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738963.1 8349915 D 1246995 CDS YP_008738964.1 556570539 17448328 8351076..8351924 1 NC_022657.1 hypothetical protein 8351924 17448328 AFR_38285 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738964.1 8351076 D 1246995 CDS YP_008738965.1 556570540 17448330 8352159..8352962 1 NC_022657.1 COG0300 Short-chain dehydrogenases of various substrate specificities; short-chain dehydrogenase/reductase SDR 8352962 17448330 AFR_38290 Actinoplanes friuliensis DSM 7358 short-chain dehydrogenase/reductase SDR YP_008738965.1 8352159 D 1246995 CDS YP_008738966.1 556570541 17448331 complement(8352947..8354053) 1 NC_022657.1 hypothetical protein 8354053 17448331 AFR_38295 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738966.1 8352947 R 1246995 CDS YP_008738967.1 556570542 17448332 8354184..8354399 1 NC_022657.1 hypothetical protein 8354399 17448332 AFR_38300 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738967.1 8354184 D 1246995 CDS YP_008738968.1 556570543 17448334 complement(8354650..8357607) 1 NC_022657.1 COG1615 Uncharacterized conserved protein; hypothetical protein 8357607 17448334 AFR_38305 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738968.1 8354650 R 1246995 CDS YP_008738969.1 556570544 17448335 complement(8357743..8358771) 1 NC_022657.1 COG3480 Predicted secreted protein containing a PDZ domain; PDZ domain-containing protein 8358771 17448335 AFR_38310 Actinoplanes friuliensis DSM 7358 PDZ domain-containing protein YP_008738969.1 8357743 R 1246995 CDS YP_008738970.1 556570545 17448336 8358862..8360097 1 NC_022657.1 COG5282 Uncharacterized conserved protein; hypothetical protein 8360097 17448336 AFR_38315 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738970.1 8358862 D 1246995 CDS YP_008738971.1 556570546 17448337 complement(8360325..8360900) 1 NC_022657.1 hypothetical protein 8360900 17448337 AFR_38320 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738971.1 8360325 R 1246995 CDS YP_008738972.1 556570547 17448338 complement(8360928..8361431) 1 NC_022657.1 COG1451 Predicted metal-dependent hydrolase; hypothetical protein 8361431 17448338 AFR_38325 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738972.1 8360928 R 1246995 CDS YP_008738973.1 556570548 17448339 8361925..8362086 1 NC_022657.1 hypothetical protein 8362086 17448339 AFR_38330 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738973.1 8361925 D 1246995 CDS YP_008738974.1 556570549 17448340 8362327..8363478 1 NC_022657.1 hypothetical protein 8363478 17448340 AFR_38335 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738974.1 8362327 D 1246995 CDS YP_008738975.1 556570550 17448341 8363641..8364987 1 NC_022657.1 COG0661 Predicted unusual protein kinase; putative ubiquinone biosynthesis protein ubiB 8364987 17448341 AFR_38340 Actinoplanes friuliensis DSM 7358 putative ubiquinone biosynthesis protein ubiB YP_008738975.1 8363641 D 1246995 CDS YP_008738976.1 556570551 17448342 complement(8366648..8367010) 1 NC_022657.1 putative WhiB-family transcriptional regulator 8367010 17448342 AFR_38345 Actinoplanes friuliensis DSM 7358 putative WhiB-family transcriptional regulator YP_008738976.1 8366648 R 1246995 CDS YP_008738977.1 556570552 17448343 complement(8367150..8367455) 1 NC_022657.1 hypothetical protein 8367455 17448343 AFR_38350 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738977.1 8367150 R 1246995 CDS YP_008738978.1 556570553 17448344 complement(8367570..8369714) 1 NC_022657.1 COG0210 Superfamily I DNA and RNA helicases; putative ATP-dependent DNA helicase 8369714 17448344 AFR_38355 Actinoplanes friuliensis DSM 7358 putative ATP-dependent DNA helicase YP_008738978.1 8367570 R 1246995 CDS YP_008738979.1 556570554 17448345 8369796..8370038 1 NC_022657.1 COG0695 Glutaredoxin and related proteins; glutaredoxin-like protein 8370038 17448345 AFR_38360 Actinoplanes friuliensis DSM 7358 glutaredoxin-like protein YP_008738979.1 8369796 D 1246995 CDS YP_008738980.1 556570555 17448346 complement(8370057..8371001) 1 NC_022657.1 hypothetical protein 8371001 17448346 AFR_38365 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738980.1 8370057 R 1246995 CDS YP_008738981.1 556570556 17448347 complement(8371102..8371755) 1 NC_022657.1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; LuxR family transcriptional regulator 8371755 17448347 AFR_38370 Actinoplanes friuliensis DSM 7358 LuxR family transcriptional regulator YP_008738981.1 8371102 R 1246995 CDS YP_008738982.1 556570557 17448348 complement(8371752..8372969) 1 NC_022657.1 COG4585 Signal transduction histidine kinase; ATP-binding region, ATPase-like protein 8372969 17448348 AFR_38375 Actinoplanes friuliensis DSM 7358 ATP-binding region, ATPase-like protein YP_008738982.1 8371752 R 1246995 CDS YP_008738983.1 556570558 17448349 complement(8372950..8373702) 1 NC_022657.1 hypothetical protein 8373702 17448349 AFR_38380 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738983.1 8372950 R 1246995 CDS YP_008738984.1 556570559 17448350 complement(8374018..8374899) 1 NC_022657.1 COG5285 Protein involved in biosynthesis of mitomycin antibiotics/polyketide fumonisin; Ectoine hydroxylase 8374899 17448350 AFR_38385 Actinoplanes friuliensis DSM 7358 Ectoine hydroxylase YP_008738984.1 8374018 R 1246995 CDS YP_008738985.1 556570560 17448351 complement(8375003..8375983) 1 NC_022657.1 COG2816 NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding; putative NUDIX hydrolase 8375983 17448351 AFR_38390 Actinoplanes friuliensis DSM 7358 putative NUDIX hydrolase YP_008738985.1 8375003 R 1246995 CDS YP_008738986.1 556570561 17448352 complement(8375980..8377296) 1 NC_022657.1 COG0612 Predicted Zn-dependent peptidases; putative M16-family peptidase 8377296 17448352 AFR_38395 Actinoplanes friuliensis DSM 7358 putative M16-family peptidase YP_008738986.1 8375980 R 1246995 CDS YP_008738987.1 556570562 17448353 complement(8377293..8378606) 1 NC_022657.1 COG0612 Predicted Zn-dependent peptidases; peptidase m16 domain-containing protein 8378606 17448353 AFR_38400 Actinoplanes friuliensis DSM 7358 peptidase m16 domain-containing protein YP_008738987.1 8377293 R 1246995 CDS YP_008738988.1 556570563 17448354 8378762..8379115 1 NC_022657.1 hypothetical protein 8379115 17448354 AFR_38405 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738988.1 8378762 D 1246995 CDS YP_008738989.1 556570564 17448355 8379121..8380392 1 NC_022657.1 COG1678 Putative transcriptional regulator; oligopeptide-binding lipoprotein 8380392 17448355 AFR_38410 Actinoplanes friuliensis DSM 7358 oligopeptide-binding lipoprotein YP_008738989.1 8379121 D 1246995 CDS YP_008738990.1 556570565 17448356 8380389..8382464 1 NC_022657.1 hypothetical protein 8382464 17448356 AFR_38415 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738990.1 8380389 D 1246995 CDS YP_008738991.1 556570566 17448357 8382520..8382897 1 NC_022657.1 hypothetical protein 8382897 17448357 AFR_38420 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738991.1 8382520 D 1246995 CDS YP_008738992.1 556570567 17448358 8382966..8383715 1 NC_022657.1 COG0726 Predicted xylanase/chitin deacetylase; putative polysaccharide deacetylase 8383715 17448358 AFR_38425 Actinoplanes friuliensis DSM 7358 putative polysaccharide deacetylase YP_008738992.1 8382966 D 1246995 CDS YP_008738993.1 556570568 17448359 complement(8383712..8384200) 1 NC_022657.1 hypothetical protein 8384200 17448359 AFR_38430 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738993.1 8383712 R 1246995 CDS YP_008738994.1 556570569 17448360 8384340..8384753 1 NC_022657.1 COG1959 Predicted transcriptional regulator; putative transcriptional regulator 8384753 17448360 AFR_38435 Actinoplanes friuliensis DSM 7358 putative transcriptional regulator YP_008738994.1 8384340 D 1246995 CDS YP_008738995.1 556570570 17448361 8384762..8385820 1 NC_022657.1 COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components; putative ABC transporter substrate-binding protein 8385820 17448361 AFR_38440 Actinoplanes friuliensis DSM 7358 putative ABC transporter substrate-binding protein YP_008738995.1 8384762 D 1246995 CDS YP_008738996.1 556570571 17448362 8385878..8386660 1 NC_022657.1 COG1116 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component; sulfonate/nitrate/taurine transport system ATP-binding protein 8386660 17448362 AFR_38445 Actinoplanes friuliensis DSM 7358 sulfonate/nitrate/taurine transport system ATP-binding protein YP_008738996.1 8385878 D 1246995 CDS YP_008738997.1 556570572 17448363 8386650..8387594 1 NC_022657.1 COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component; ABC transporter permease 8387594 17448363 AFR_38450 Actinoplanes friuliensis DSM 7358 ABC transporter permease YP_008738997.1 8386650 D 1246995 CDS YP_008738998.1 556570573 17448364 complement(8387591..8388319) 1 NC_022657.1 hypothetical protein 8388319 17448364 AFR_38455 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008738998.1 8387591 R 1246995 CDS YP_008738999.1 556570574 17448365 8388811..8389542 1 NC_022657.1 COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase; putative phospholipid/glycerol acyltransferase 8389542 17448365 AFR_38460 Actinoplanes friuliensis DSM 7358 putative phospholipid/glycerol acyltransferase YP_008738999.1 8388811 D 1246995 CDS YP_008739000.1 556570575 17448366 complement(8389604..8389807) 1 NC_022657.1 COG1278 Cold shock proteins; cold-shock DNA-binding domain-containing protein 8389807 17448366 AFR_38465 Actinoplanes friuliensis DSM 7358 cold-shock DNA-binding domain-containing protein YP_008739000.1 8389604 R 1246995 CDS YP_008739001.1 556570576 17448367 8390046..8390438 1 NC_022657.1 hypothetical protein 8390438 17448367 AFR_38470 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739001.1 8390046 D 1246995 CDS YP_008739002.1 556570577 17448368 complement(8390439..8393945) 1 NC_022657.1 COG0210 Superfamily I DNA and RNA helicases; putative ATP-dependent DNA helicase 8393945 17448368 AFR_38475 Actinoplanes friuliensis DSM 7358 putative ATP-dependent DNA helicase YP_008739002.1 8390439 R 1246995 CDS YP_008739003.1 556570578 17448369 complement(8393876..8398297) 1 NC_022657.1 COG0210 Superfamily I DNA and RNA helicases; UvrD/REP helicase 8398297 17448369 AFR_38480 Actinoplanes friuliensis DSM 7358 UvrD/REP helicase YP_008739003.1 8393876 R 1246995 CDS YP_008739004.1 556570579 17448370 complement(8398335..8399354) 1 NC_022657.1 COG1609 Transcriptional regulators; LacI family transcriptional regulator 8399354 17448370 AFR_38485 Actinoplanes friuliensis DSM 7358 LacI family transcriptional regulator YP_008739004.1 8398335 R 1246995 CDS YP_008739005.1 556570580 17448371 complement(8399556..8400311) 1 NC_022657.1 COG4312 Uncharacterized protein conserved in bacteria; hypothetical protein 8400311 17448371 AFR_38490 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739005.1 8399556 R 1246995 CDS YP_008739006.1 556570581 17448372 complement(8400352..8400891) 1 NC_022657.1 COG1611 Predicted Rossmann fold nucleotide-binding protein; hypothetical protein 8400891 17448372 AFR_38495 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739006.1 8400352 R 1246995 CDS YP_008739007.1 556570582 17448373 complement(8400893..8401564) 1 NC_022657.1 COG1611 Predicted Rossmann fold nucleotide-binding protein; hypothetical protein 8401564 17448373 AFR_38500 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739007.1 8400893 R 1246995 CDS YP_008739008.1 556570583 17448374 complement(8402042..8403118) 1 NC_022657.1 COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases; succinyl-diaminopimelate desuccinylase 8403118 17448374 AFR_38505 Actinoplanes friuliensis DSM 7358 succinyl-diaminopimelate desuccinylase YP_008739008.1 8402042 R 1246995 CDS YP_008739009.1 556570584 17448375 8403239..8403538 1 NC_022657.1 hypothetical protein 8403538 17448375 AFR_38510 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739009.1 8403239 D 1246995 CDS YP_008739010.1 556570585 17448376 8403535..8405088 1 NC_022657.1 hypothetical protein 8405088 17448376 AFR_38515 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739010.1 8403535 D 1246995 CDS YP_008739011.1 556570586 17448377 8405085..8405441 1 NC_022657.1 hypothetical protein 8405441 17448377 AFR_38520 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739011.1 8405085 D 1246995 CDS YP_008739012.1 556570587 17448378 complement(8405428..8405832) 1 NC_022657.1 hypothetical protein 8405832 17448378 AFR_38525 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739012.1 8405428 R 1246995 CDS YP_008739013.1 556570588 17448379 8405926..8406873 1 NC_022657.1 COG2171 Tetrahydrodipicolinate N-succinyltransferase; putative tetrahydrodipicolinate N-succinyltransferase 8406873 17448379 AFR_38530 Actinoplanes friuliensis DSM 7358 putative tetrahydrodipicolinate N-succinyltransferase YP_008739013.1 8405926 D 1246995 CDS YP_008739014.1 556570589 17448380 complement(8406870..8407724) 1 NC_022657.1 COG0583 Transcriptional regulator; chromosome replication initiation inhibitor protein 8407724 17448380 AFR_38535 Actinoplanes friuliensis DSM 7358 chromosome replication initiation inhibitor protein YP_008739014.1 8406870 R 1246995 CDS YP_008739015.1 556570590 17448381 8407796..8408389 1 NC_022657.1 COG1279 Lysine efflux permease; Arginine exporter protein argO 8408389 17448381 AFR_38540 Actinoplanes friuliensis DSM 7358 Arginine exporter protein argO YP_008739015.1 8407796 D 1246995 CDS YP_008739016.1 556570591 17448382 8408475..8411111 1 NC_022657.1 hypothetical protein 8411111 17448382 AFR_38545 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739016.1 8408475 D 1246995 CDS YP_008739017.1 556570592 17448383 complement(8411166..8411579) 1 NC_022657.1 COG0346 Lactoylglutathione lyase and related lyases; lyase 8411579 17448383 AFR_38550 Actinoplanes friuliensis DSM 7358 lyase YP_008739017.1 8411166 R 1246995 CDS YP_008739018.1 556570593 17448384 complement(8411589..8412002) 1 NC_022657.1 COG2207 AraC-type DNA-binding domain-containing proteins; AraC family transcriptional regulator 8412002 17448384 AFR_38555 Actinoplanes friuliensis DSM 7358 AraC family transcriptional regulator YP_008739018.1 8411589 R 1246995 CDS YP_008739019.1 556570594 17448385 complement(8412005..8412523) 1 NC_022657.1 hypothetical protein 8412523 17448385 AFR_38560 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739019.1 8412005 R 1246995 CDS YP_008739020.1 556570595 17448386 8412597..8413634 1 NC_022657.1 COG0789 Predicted transcriptional regulators; putative MerR-family transcriptional regulator 8413634 17448386 AFR_38565 Actinoplanes friuliensis DSM 7358 putative MerR-family transcriptional regulator YP_008739020.1 8412597 D 1246995 CDS YP_008739021.1 556570596 17448387 8413647..8414708 1 NC_022657.1 COG2008 Threonine aldolase; aromatic amino acid beta-eliminating lyase/threonine aldolase 8414708 17448387 AFR_38570 Actinoplanes friuliensis DSM 7358 aromatic amino acid beta-eliminating lyase/threonine aldolase YP_008739021.1 8413647 D 1246995 CDS YP_008739022.1 556570597 17448388 8414751..8415608 1 NC_022657.1 COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases); Putative oxidoreductase ydbC 8415608 17448388 AFR_38575 Actinoplanes friuliensis DSM 7358 Putative oxidoreductase ydbC YP_008739022.1 8414751 D 1246995 CDS YP_008739023.1 556570598 17448389 complement(8415610..8416470) 1 NC_022657.1 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; RNA polymerase factor sigma-70 8416470 17448389 AFR_38580 Actinoplanes friuliensis DSM 7358 RNA polymerase factor sigma-70 YP_008739023.1 8415610 R 1246995 CDS YP_008739024.1 556570599 17448390 complement(8416470..8417195) 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); short-chain dehydrogenase/reductase SDR 8417195 17448390 AFR_38585 Actinoplanes friuliensis DSM 7358 short-chain dehydrogenase/reductase SDR YP_008739024.1 8416470 R 1246995 CDS YP_008739025.1 556570600 17448391 8417292..8417582 1 NC_022657.1 COG0640 Predicted transcriptional regulators; Transcriptional regulator, ArsR family protein 8417582 17448391 AFR_38590 Actinoplanes friuliensis DSM 7358 Transcriptional regulator, ArsR family protein YP_008739025.1 8417292 D 1246995 CDS YP_008739026.1 556570601 17448392 8417579..8417959 1 NC_022657.1 COG3832 Uncharacterized conserved protein; hypothetical protein 8417959 17448392 AFR_38595 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739026.1 8417579 D 1246995 CDS YP_008739027.1 556570602 17448393 complement(8417931..8418623) 1 NC_022657.1 hypothetical protein 8418623 17448393 AFR_38600 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739027.1 8417931 R 1246995 CDS YP_008739028.1 556570603 17448394 8418703..8419428 1 NC_022657.1 COG0500 SAM-dependent methyltransferases; putative methyltransferase 8419428 17448394 AFR_38605 Actinoplanes friuliensis DSM 7358 putative methyltransferase YP_008739028.1 8418703 D 1246995 CDS YP_008739029.1 556570604 17448395 8419570..8420766 1 NC_022657.1 COG3572 Gamma-glutamylcysteine synthetase; glutamate--cysteine ligase GCS2 8420766 17448395 AFR_38610 Actinoplanes friuliensis DSM 7358 glutamate--cysteine ligase GCS2 YP_008739029.1 8419570 D 1246995 CDS YP_008739030.1 556570605 17448396 8420763..8422067 1 NC_022657.1 COG1262 Uncharacterized conserved protein; hypothetical protein 8422067 17448396 AFR_38615 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739030.1 8420763 D 1246995 CDS YP_008739031.1 556570606 17448397 8422067..8422813 1 NC_022657.1 COG0121 Predicted glutamine amidotransferase; hypothetical protein 8422813 17448397 AFR_38620 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739031.1 8422067 D 1246995 CDS YP_008739032.1 556570607 17448398 8422810..8423775 1 NC_022657.1 COG4301 Uncharacterized conserved protein; hypothetical protein 8423775 17448398 AFR_38625 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739032.1 8422810 D 1246995 CDS YP_008739033.1 556570608 17448399 complement(8423777..8424511) 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); 3-oxoacyl-[acyl-carrier-protein] reductase 8424511 17448399 AFR_38630 Actinoplanes friuliensis DSM 7358 3-oxoacyl-[acyl-carrier-protein] reductase YP_008739033.1 8423777 R 1246995 CDS YP_008739034.1 556570609 17448400 complement(8424568..8425509) 1 NC_022657.1 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; RNA polymerase factor sigma-70 8425509 17448400 AFR_38635 Actinoplanes friuliensis DSM 7358 RNA polymerase factor sigma-70 YP_008739034.1 8424568 R 1246995 CDS YP_008739035.1 556570610 17448401 8425640..8425825 1 NC_022657.1 hypothetical protein 8425825 17448401 AFR_38640 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739035.1 8425640 D 1246995 CDS YP_008739036.1 556570611 17448402 8425835..8426461 1 NC_022657.1 COG0122 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase; HhH-GPD family protein 8426461 17448402 AFR_38645 Actinoplanes friuliensis DSM 7358 HhH-GPD family protein YP_008739036.1 8425835 D 1246995 CDS YP_008739037.1 556570612 17448403 8426539..8427672 1 NC_022657.1 COG1874 Beta-galactosidase; hypothetical protein 8427672 17448403 AFR_38650 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739037.1 8426539 D 1246995 CDS YP_008739038.1 556570613 17448404 complement(8427638..8428768) 1 NC_022657.1 COG0438 Glycosyltransferase; group 1 glycosyl transferase 8428768 17448404 AFR_38655 Actinoplanes friuliensis DSM 7358 group 1 glycosyl transferase YP_008739038.1 8427638 R 1246995 CDS YP_008739039.1 556570614 17448405 complement(8428765..8430162) 1 NC_022657.1 hypothetical protein 8430162 17448405 AFR_38660 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739039.1 8428765 R 1246995 CDS YP_008739040.1 556570615 17448406 complement(8430159..8431835) 1 NC_022657.1 hypothetical protein 8431835 17448406 AFR_38665 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739040.1 8430159 R 1246995 CDS YP_008739041.1 556570616 17448407 complement(8431829..8432587) 1 NC_022657.1 hypothetical protein 8432587 17448407 AFR_38670 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739041.1 8431829 R 1246995 CDS YP_008739042.1 556570617 17448408 complement(8432575..8434068) 1 NC_022657.1 COG0438 Glycosyltransferase; glycosyl transferase group 1 8434068 17448408 AFR_38675 Actinoplanes friuliensis DSM 7358 glycosyl transferase group 1 YP_008739042.1 8432575 R 1246995 CDS YP_008739043.1 556570618 17448409 complement(8434065..8434736) 1 NC_022657.1 COG0463 Glycosyltransferases involved in cell wall biogenesis; family 2 glycosyl transferase 8434736 17448409 AFR_38680 Actinoplanes friuliensis DSM 7358 family 2 glycosyl transferase YP_008739043.1 8434065 R 1246995 CDS YP_008739044.1 556570619 17448410 8434964..8435686 1 NC_022657.1 Seed lectin 8435686 17448410 AFR_38685 Actinoplanes friuliensis DSM 7358 Seed lectin YP_008739044.1 8434964 D 1246995 CDS YP_008739045.1 556570620 17448411 8436235..8436744 1 NC_022657.1 hypothetical protein 8436744 17448411 AFR_38690 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739045.1 8436235 D 1246995 CDS YP_008739046.1 556570621 17448412 8436810..8437295 1 NC_022657.1 hypothetical protein 8437295 17448412 AFR_38695 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739046.1 8436810 D 1246995 CDS YP_008739047.1 556570622 17448413 8438597..8439232 1 NC_022657.1 hypothetical protein 8439232 17448413 AFR_38700 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739047.1 8438597 D 1246995 CDS YP_008739048.1 556570623 17448414 complement(8439189..8439704) 1 NC_022657.1 hypothetical protein 8439704 17448414 AFR_38705 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739048.1 8439189 R 1246995 CDS YP_008739049.1 556570624 17448415 complement(8439870..8441138) 1 NC_022657.1 hypothetical protein 8441138 17448415 AFR_38710 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739049.1 8439870 R 1246995 CDS YP_008739050.1 556570625 17448416 8441262..8442116 1 NC_022657.1 COG0656 Aldo/keto reductases, related to diketogulonate reductase; 2,5-didehydrogluconate reductase 8442116 17448416 AFR_38715 Actinoplanes friuliensis DSM 7358 2,5-didehydrogluconate reductase YP_008739050.1 8441262 D 1246995 CDS YP_008739051.1 556570626 17448417 complement(8442118..8442765) 1 NC_022657.1 COG2968 Uncharacterized conserved protein; hypothetical protein 8442765 17448417 AFR_38720 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739051.1 8442118 R 1246995 CDS YP_008739052.1 556570627 17448418 complement(8442775..8443779) 1 NC_022657.1 COG1404 Subtilisin-like serine proteases; peptidase S8/S53 subtilisin kexin sedolisin 8443779 17448418 AFR_38725 Actinoplanes friuliensis DSM 7358 peptidase S8/S53 subtilisin kexin sedolisin YP_008739052.1 8442775 R 1246995 CDS YP_008739053.1 556570628 17448419 complement(8444070..8445611) 1 NC_022657.1 hypothetical protein 8445611 17448419 AFR_38730 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739053.1 8444070 R 1246995 CDS YP_008739054.1 556570629 17448420 complement(8445608..8446024) 1 NC_022657.1 hypothetical protein 8446024 17448420 AFR_38735 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739054.1 8445608 R 1246995 CDS YP_008739055.1 556570630 17448421 complement(8446107..8447192) 1 NC_022657.1 COG0436 Aspartate/tyrosine/aromatic aminotransferase; N-succinyldiaminopimelate aminotransferase 8447192 17448421 AFR_38740 Actinoplanes friuliensis DSM 7358 N-succinyldiaminopimelate aminotransferase YP_008739055.1 8446107 R 1246995 CDS YP_008739056.1 556570631 17448422 complement(8447197..8447520) 1 NC_022657.1 COG1146 Ferredoxin; Ferredoxin 1 8447520 17448422 AFR_38745 Actinoplanes friuliensis DSM 7358 Ferredoxin 1 YP_008739056.1 8447197 R 1246995 CDS YP_008739057.1 556570632 17448423 8447709..8448575 1 NC_022657.1 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; putative GCN5-related N-acetyltransferase 8448575 17448423 AFR_38750 Actinoplanes friuliensis DSM 7358 putative GCN5-related N-acetyltransferase YP_008739057.1 8447709 D 1246995 CDS YP_008739058.1 556570633 17448424 complement(8448544..8449380) 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); short-chain dehydrogenase/reductase SDR 8449380 17448424 AFR_38755 Actinoplanes friuliensis DSM 7358 short-chain dehydrogenase/reductase SDR YP_008739058.1 8448544 R 1246995 CDS YP_008739059.1 556570634 17448425 8449478..8450338 1 NC_022657.1 COG0583 Transcriptional regulator; LysR family transcriptional regulator 8450338 17448425 AFR_38760 Actinoplanes friuliensis DSM 7358 LysR family transcriptional regulator YP_008739059.1 8449478 D 1246995 CDS YP_008739060.1 556570635 17448426 complement(8450335..8450784) 1 NC_022657.1 hypothetical protein 8450784 17448426 AFR_38765 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739060.1 8450335 R 1246995 CDS YP_008739061.1 556570636 17448427 complement(8450819..8452477) 1 NC_022657.1 COG2720 Uncharacterized vancomycin resistance protein; VanW family protein 8452477 17448427 AFR_38770 Actinoplanes friuliensis DSM 7358 VanW family protein YP_008739061.1 8450819 R 1246995 CDS YP_008739062.1 556570637 17448428 complement(8452560..8453009) 1 NC_022657.1 hypothetical protein 8453009 17448428 AFR_38775 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739062.1 8452560 R 1246995 CDS YP_008739063.1 556570638 17448429 complement(8453006..8453854) 1 NC_022657.1 COG2120 Uncharacterized proteins, LmbE homologs; LmbE family protein 8453854 17448429 AFR_38780 Actinoplanes friuliensis DSM 7358 LmbE family protein YP_008739063.1 8453006 R 1246995 CDS YP_008739064.1 556570639 17448430 8453961..8455718 1 NC_022657.1 COG1506 Dipeptidyl aminopeptidases/acylaminoacyl-peptidases; putative peptidase 8455718 17448430 AFR_38785 Actinoplanes friuliensis DSM 7358 putative peptidase YP_008739064.1 8453961 D 1246995 CDS YP_008739065.1 556570640 17448431 8455792..8456310 1 NC_022657.1 hypothetical protein 8456310 17448431 AFR_38790 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739065.1 8455792 D 1246995 CDS YP_008739066.1 556570641 17448432 complement(8456307..8457854) 1 NC_022657.1 COG2199 FOG: GGDEF domain; Cellulose synthesis regulatory protein 8457854 17448432 AFR_38795 Actinoplanes friuliensis DSM 7358 Cellulose synthesis regulatory protein YP_008739066.1 8456307 R 1246995 CDS YP_008739067.1 556570642 17448433 8457948..8459390 1 NC_022657.1 COG0312 Predicted Zn-dependent proteases and their inactivated homologs; putative modulator of DNA gyrase 8459390 17448433 AFR_38800 Actinoplanes friuliensis DSM 7358 putative modulator of DNA gyrase YP_008739067.1 8457948 D 1246995 CDS YP_008739068.1 556570643 17448434 8459387..8460763 1 NC_022657.1 COG0312 Predicted Zn-dependent proteases and their inactivated homologs; Protein pmbA 8460763 17448434 AFR_38805 Actinoplanes friuliensis DSM 7358 Protein pmbA YP_008739068.1 8459387 D 1246995 CDS YP_008739069.1 556570644 17448435 8461075..8462079 1 NC_022657.1 hypothetical protein 8462079 17448435 AFR_38810 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739069.1 8461075 D 1246995 CDS YP_008739070.1 556570645 17448436 8462215..8463021 1 NC_022657.1 succinate dehydrogenase membrane anchor subunit 8463021 17448436 AFR_38815 Actinoplanes friuliensis DSM 7358 succinate dehydrogenase membrane anchor subunit YP_008739070.1 8462215 D 1246995 CDS YP_008739071.1 556570646 17448437 8463031..8464941 1 NC_022657.1 COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit; succinate dehydrogenase flavoprotein subunit 8464941 sdhA 17448437 sdhA Actinoplanes friuliensis DSM 7358 succinate dehydrogenase flavoprotein subunit YP_008739071.1 8463031 D 1246995 CDS YP_008739072.1 556570647 17448438 8464941..8465963 1 NC_022657.1 COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit; fumarate reductase iron-sulfur subunit 8465963 17448438 AFR_38825 Actinoplanes friuliensis DSM 7358 fumarate reductase iron-sulfur subunit YP_008739072.1 8464941 D 1246995 CDS YP_008739073.1 556570648 17448439 8466082..8467164 1 NC_022657.1 hypothetical protein 8467164 17448439 AFR_38830 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739073.1 8466082 D 1246995 CDS YP_008739074.1 556570649 17448440 8467166..8468221 1 NC_022657.1 hypothetical protein 8468221 17448440 AFR_38835 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739074.1 8467166 D 1246995 CDS YP_008739075.1 556570650 17448441 complement(8468225..8469367) 1 NC_022657.1 COG2339 Predicted membrane protein; hypothetical protein 8469367 17448441 AFR_38840 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739075.1 8468225 R 1246995 CDS YP_008739076.1 556570651 17448442 complement(8469364..8469960) 1 NC_022657.1 hypothetical protein 8469960 17448442 AFR_38845 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739076.1 8469364 R 1246995 CDS YP_008739077.1 556570652 17448443 8470048..8470776 1 NC_022657.1 hypothetical protein 8470776 17448443 AFR_38850 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739077.1 8470048 D 1246995 CDS YP_008739078.1 556570653 17448444 8470853..8471467 1 NC_022657.1 COG3145 Alkylated DNA repair protein; hypothetical protein 8471467 17448444 AFR_38855 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739078.1 8470853 D 1246995 CDS YP_008739079.1 556570654 17448445 8471617..8472342 1 NC_022657.1 COG0411 ABC-type branched-chain amino acid transport systems, ATPase component; putative ABC transporter ATP-binding protein 8472342 17448445 AFR_38860 Actinoplanes friuliensis DSM 7358 putative ABC transporter ATP-binding protein YP_008739079.1 8471617 D 1246995 CDS YP_008739080.1 556570655 17448446 8472339..8473055 1 NC_022657.1 COG0410 ABC-type branched-chain amino acid transport systems, ATPase component; putative ABC transporter ATP-binding protein 8473055 17448446 AFR_38865 Actinoplanes friuliensis DSM 7358 putative ABC transporter ATP-binding protein YP_008739080.1 8472339 D 1246995 CDS YP_008739081.1 556570656 17448447 8473068..8473946 1 NC_022657.1 COG0559 Branched-chain amino acid ABC-type transport system, permease components; putative branched-chain amino acid ABC transporter permease 8473946 17448447 AFR_38870 Actinoplanes friuliensis DSM 7358 putative branched-chain amino acid ABC transporter permease YP_008739081.1 8473068 D 1246995 CDS YP_008739082.1 556570657 17448448 8474024..8474992 1 NC_022657.1 COG4177 ABC-type branched-chain amino acid transport system, permease component; putative branched-chain amino acid ABC transporter permease 8474992 17448448 AFR_38875 Actinoplanes friuliensis DSM 7358 putative branched-chain amino acid ABC transporter permease YP_008739082.1 8474024 D 1246995 CDS YP_008739083.1 556570658 17448449 8474989..8476257 1 NC_022657.1 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component; putative ABC transporter substrate-binding protein 8476257 17448449 AFR_38880 Actinoplanes friuliensis DSM 7358 putative ABC transporter substrate-binding protein YP_008739083.1 8474989 D 1246995 CDS YP_008739084.1 556570659 17448450 8476384..8477139 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); 3-ketoacyl-(acyl-carrier-protein) reductase 8477139 fabG 17448450 fabG Actinoplanes friuliensis DSM 7358 3-ketoacyl-(acyl-carrier-protein) reductase YP_008739084.1 8476384 D 1246995 CDS YP_008739085.1 556570660 17448451 8477136..8477912 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); putative short-chain dehydrogenase 8477912 17448451 AFR_38890 Actinoplanes friuliensis DSM 7358 putative short-chain dehydrogenase YP_008739085.1 8477136 D 1246995 CDS YP_008739086.1 556570661 17448452 8477909..8478916 1 NC_022657.1 COG3173 Predicted aminoglycoside phosphotransferase; putative phosphotransferase 8478916 17448452 AFR_38895 Actinoplanes friuliensis DSM 7358 putative phosphotransferase YP_008739086.1 8477909 D 1246995 CDS YP_008739087.1 556570662 17448453 8478916..8480121 1 NC_022657.1 COG1960 Acyl-CoA dehydrogenases; acyl-CoA dehydrogenase domain-containing protein 8480121 17448453 AFR_38900 Actinoplanes friuliensis DSM 7358 acyl-CoA dehydrogenase domain-containing protein YP_008739087.1 8478916 D 1246995 CDS YP_008739088.1 556570663 17448454 8480121..8480723 1 NC_022657.1 COG1309 Transcriptional regulator; hypothetical protein 8480723 17448454 AFR_38905 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739088.1 8480121 D 1246995 CDS YP_008739089.1 556570664 17448455 8480757..8481434 1 NC_022657.1 hypothetical protein 8481434 17448455 AFR_38910 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739089.1 8480757 D 1246995 CDS YP_008739090.1 556570665 17448456 8481431..8482156 1 NC_022657.1 hypothetical protein 8482156 17448456 AFR_38915 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739090.1 8481431 D 1246995 CDS YP_008739091.1 556570666 17448457 complement(8482223..8483239) 1 NC_022657.1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; erythropoiesis-stimulating protein 8483239 17448457 AFR_38920 Actinoplanes friuliensis DSM 7358 erythropoiesis-stimulating protein YP_008739091.1 8482223 R 1246995 CDS YP_008739092.1 556570667 17448458 8483612..8484232 1 NC_022657.1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; Transcription factor 8484232 17448458 AFR_38925 Actinoplanes friuliensis DSM 7358 Transcription factor YP_008739092.1 8483612 D 1246995 CDS YP_008739093.1 556570668 17448459 8484229..8485212 1 NC_022657.1 COG4585 Signal transduction histidine kinase; two-component system histidine kinase 8485212 17448459 AFR_38930 Actinoplanes friuliensis DSM 7358 two-component system histidine kinase YP_008739093.1 8484229 D 1246995 CDS YP_008739094.1 556570669 17448460 complement(8485209..8486228) 1 NC_022657.1 COG0451 Nucleoside-diphosphate-sugar epimerases; NAD-dependent epimerase/dehydratase 8486228 17448460 AFR_38935 Actinoplanes friuliensis DSM 7358 NAD-dependent epimerase/dehydratase YP_008739094.1 8485209 R 1246995 CDS YP_008739095.1 556570670 17448461 complement(8486225..8487442) 1 NC_022657.1 hypothetical protein 8487442 17448461 AFR_38940 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739095.1 8486225 R 1246995 CDS YP_008739096.1 556570671 17448462 complement(8487435..8488712) 1 NC_022657.1 COG1541 Coenzyme F390 synthetase; AMP-dependent synthetase and ligase 8488712 17448462 AFR_38945 Actinoplanes friuliensis DSM 7358 AMP-dependent synthetase and ligase YP_008739096.1 8487435 R 1246995 CDS YP_008739097.1 556570672 17448463 complement(8488715..8489413) 1 NC_022657.1 hypothetical protein 8489413 17448463 AFR_38950 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739097.1 8488715 R 1246995 CDS YP_008739098.1 556570673 17448464 complement(8489410..8490624) 1 NC_022657.1 COG0439 Biotin carboxylase; biotin carboxylase 8490624 17448464 AFR_38955 Actinoplanes friuliensis DSM 7358 biotin carboxylase YP_008739098.1 8489410 R 1246995 CDS YP_008739099.1 556570674 17448465 complement(8490621..8491610) 1 NC_022657.1 COG0463 Glycosyltransferases involved in cell wall biogenesis; glycosyl transferase 8491610 17448465 AFR_38960 Actinoplanes friuliensis DSM 7358 glycosyl transferase YP_008739099.1 8490621 R 1246995 CDS YP_008739100.1 556570675 17448466 complement(8491603..8492328) 1 NC_022657.1 COG3483 Tryptophan 2,3-dioxygenase (vermilion); tryptophan 2,3-dioxygenase (vermilion) 8492328 17448466 AFR_38965 Actinoplanes friuliensis DSM 7358 tryptophan 2,3-dioxygenase (vermilion) YP_008739100.1 8491603 R 1246995 CDS YP_008739101.1 556570676 17448467 complement(8492459..8493544) 1 NC_022657.1 COG1062 Zn-dependent alcohol dehydrogenases, class III; S-(hydroxymethyl)glutathione dehydrogenase / alcohol dehydrogenase 8493544 17448467 AFR_38970 Actinoplanes friuliensis DSM 7358 S-(hydroxymethyl)glutathione dehydrogenase / alcohol dehydrogenase YP_008739101.1 8492459 R 1246995 CDS YP_008739102.1 556570677 17448468 complement(8493541..8494941) 1 NC_022657.1 COG1012 NAD-dependent aldehyde dehydrogenases; putative aldehyde dehydrogenase 8494941 17448468 AFR_38975 Actinoplanes friuliensis DSM 7358 putative aldehyde dehydrogenase YP_008739102.1 8493541 R 1246995 CDS YP_008739103.1 556570678 17448469 complement(8494938..8495585) 1 NC_022657.1 COG1309 Transcriptional regulator; TetR family transcriptional regulator 8495585 17448469 AFR_38980 Actinoplanes friuliensis DSM 7358 TetR family transcriptional regulator YP_008739103.1 8494938 R 1246995 CDS YP_008739104.1 556570679 17448470 8495640..8496812 1 NC_022657.1 COG1960 Acyl-CoA dehydrogenases; acyl-CoA dehydrogenase 8496812 17448470 AFR_38985 Actinoplanes friuliensis DSM 7358 acyl-CoA dehydrogenase YP_008739104.1 8495640 D 1246995 CDS YP_008739105.1 556570680 17448471 8496809..8498344 1 NC_022657.1 COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II; AMP-dependent synthetase and ligase 8498344 17448471 AFR_38990 Actinoplanes friuliensis DSM 7358 AMP-dependent synthetase and ligase YP_008739105.1 8496809 D 1246995 CDS YP_008739106.1 556570681 17448472 complement(8498321..8498710) 1 NC_022657.1 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; putative NUDIX hydrolase 8498710 17448472 AFR_38995 Actinoplanes friuliensis DSM 7358 putative NUDIX hydrolase YP_008739106.1 8498321 R 1246995 CDS YP_008739107.1 556570682 17448473 8498949..8499260 1 NC_022657.1 hypothetical protein 8499260 17448473 AFR_39000 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739107.1 8498949 D 1246995 CDS YP_008739108.1 556570683 17448474 8499271..8499633 1 NC_022657.1 hypothetical protein 8499633 17448474 AFR_39005 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739108.1 8499271 D 1246995 CDS YP_008739109.1 556570684 17448475 8500248..8500577 1 NC_022657.1 COG3293 Transposase and inactivated derivatives; transposase, IS4 family protein 8500577 17448475 AFR_39010 Actinoplanes friuliensis DSM 7358 transposase, IS4 family protein YP_008739109.1 8500248 D 1246995 CDS YP_008739110.1 556570685 17448476 8501158..8503935 1 NC_022657.1 COG2133 Glucose/sorbosone dehydrogenases; hypothetical protein 8503935 17448476 AFR_39015 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739110.1 8501158 D 1246995 CDS YP_008739111.1 556570686 17448477 8503959..8505617 1 NC_022657.1 COG3828 Uncharacterized protein conserved in bacteria; hypothetical protein 8505617 17448477 AFR_39020 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739111.1 8503959 D 1246995 CDS YP_008739112.1 556570687 17448478 complement(8505614..8506351) 1 NC_022657.1 Peptidase E 8506351 17448478 AFR_39025 Actinoplanes friuliensis DSM 7358 Peptidase E YP_008739112.1 8505614 R 1246995 CDS YP_008739113.1 556570688 17448479 complement(8506348..8507181) 1 NC_022657.1 COG1708 Predicted nucleotidyltransferases; hypothetical protein 8507181 17448479 AFR_39030 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739113.1 8506348 R 1246995 CDS YP_008739114.1 556570689 17448480 complement(8507168..8507974) 1 NC_022657.1 COG0500 SAM-dependent methyltransferases; type 11 methyltransferase 8507974 17448480 AFR_39035 Actinoplanes friuliensis DSM 7358 type 11 methyltransferase YP_008739114.1 8507168 R 1246995 CDS YP_008739115.1 556570690 17448481 complement(8507985..8508914) 1 NC_022657.1 COG3583 Uncharacterized protein conserved in bacteria; hypothetical protein 8508914 17448481 AFR_39040 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739115.1 8507985 R 1246995 CDS YP_008739116.1 556570691 17448482 8509286..8509783 1 NC_022657.1 hypothetical protein 8509783 17448482 AFR_39045 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739116.1 8509286 D 1246995 CDS YP_008739117.1 556570692 17448483 complement(8509851..8510423) 1 NC_022657.1 COG0431 Predicted flavoprotein; NADPH-dependent FMN reductase 8510423 17448483 AFR_39050 Actinoplanes friuliensis DSM 7358 NADPH-dependent FMN reductase YP_008739117.1 8509851 R 1246995 CDS YP_008739118.1 556570693 17448484 8510511..8511011 1 NC_022657.1 COG1846 Transcriptional regulators; putative MarR-family transcriptional regulator 8511011 17448484 AFR_39055 Actinoplanes friuliensis DSM 7358 putative MarR-family transcriptional regulator YP_008739118.1 8510511 D 1246995 CDS YP_008739119.1 556570694 17448485 8511001..8511195 1 NC_022657.1 COG1204 Superfamily II helicase; hypothetical protein 8511195 17448485 AFR_39060 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739119.1 8511001 D 1246995 CDS YP_008739120.1 556570695 17448486 8511192..8511794 1 NC_022657.1 COG1530 Ribonucleases G and E; hypothetical protein 8511794 17448486 AFR_39065 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739120.1 8511192 D 1246995 CDS YP_008739121.1 556570696 17448487 8511826..8512107 1 NC_022657.1 COG0640 Predicted transcriptional regulators; transcriptional regulator 8512107 17448487 AFR_39070 Actinoplanes friuliensis DSM 7358 transcriptional regulator YP_008739121.1 8511826 D 1246995 CDS YP_008739122.1 556570697 17448488 8512128..8512706 1 NC_022657.1 hypothetical protein 8512706 17448488 AFR_39075 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739122.1 8512128 D 1246995 CDS YP_008739123.1 556570698 17448489 complement(8512672..8514018) 1 NC_022657.1 COG0477 Permeases of the major facilitator superfamily; major facilitator superfamily protein 8514018 17448489 AFR_39080 Actinoplanes friuliensis DSM 7358 major facilitator superfamily protein YP_008739123.1 8512672 R 1246995 CDS YP_008739124.1 556570699 17448490 complement(8514058..8514453) 1 NC_022657.1 hypothetical protein 8514453 17448490 AFR_39085 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739124.1 8514058 R 1246995 CDS YP_008739125.1 556570700 17448491 complement(8514469..8514813) 1 NC_022657.1 hypothetical protein 8514813 17448491 AFR_39090 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739125.1 8514469 R 1246995 CDS YP_008739126.1 556570701 17448492 8514937..8515518 1 NC_022657.1 COG4636 Uncharacterized protein conserved in cyanobacteria; hypothetical protein 8515518 17448492 AFR_39095 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739126.1 8514937 D 1246995 CDS YP_008739127.1 556570702 17448493 complement(8515526..8515903) 1 NC_022657.1 hypothetical protein 8515903 17448493 AFR_39100 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739127.1 8515526 R 1246995 CDS YP_008739128.1 556570703 17448494 complement(8515998..8516411) 1 NC_022657.1 hypothetical protein 8516411 17448494 AFR_39105 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739128.1 8515998 R 1246995 CDS YP_008739129.1 556570704 17448495 complement(8516393..8516677) 1 NC_022657.1 hypothetical protein 8516677 17448495 AFR_39110 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739129.1 8516393 R 1246995 CDS YP_008739130.1 556570705 17448496 complement(8516723..8517808) 1 NC_022657.1 COG0012 Predicted GTPase, probable translation factor; GTP-binding protein YchF 8517808 17448496 AFR_39115 Actinoplanes friuliensis DSM 7358 GTP-binding protein YchF YP_008739130.1 8516723 R 1246995 CDS YP_008739131.1 556570706 17448497 complement(8517820..8518941) 1 NC_022657.1 hypothetical protein 8518941 17448497 AFR_39120 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739131.1 8517820 R 1246995 CDS YP_008739132.1 556570707 17448498 complement(8518923..8519996) 1 NC_022657.1 COG1396 Predicted transcriptional regulators; hypothetical protein 8519996 17448498 AFR_39125 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739132.1 8518923 R 1246995 CDS YP_008739133.1 556570708 17448499 8520298..8520537 1 NC_022657.1 hypothetical protein 8520537 17448499 AFR_39130 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739133.1 8520298 D 1246995 CDS YP_008739134.1 556570709 17448500 8520537..8521130 1 NC_022657.1 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; N-acetyltransferase GCN5 8521130 17448500 AFR_39135 Actinoplanes friuliensis DSM 7358 N-acetyltransferase GCN5 YP_008739134.1 8520537 D 1246995 CDS YP_008739135.1 556570710 17448501 complement(8521127..8521756) 1 NC_022657.1 hypothetical protein 8521756 17448501 AFR_39140 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739135.1 8521127 R 1246995 CDS YP_008739136.1 556570711 17448502 8521799..8522605 1 NC_022657.1 COG0500 SAM-dependent methyltransferases; type 11 methyltransferase 8522605 17448502 AFR_39145 Actinoplanes friuliensis DSM 7358 type 11 methyltransferase YP_008739136.1 8521799 D 1246995 CDS YP_008739137.1 556570712 17448503 8522633..8524048 1 NC_022657.1 COG2169 Adenosine deaminase; putative ADA-like regulatory protein 8524048 17448503 AFR_39150 Actinoplanes friuliensis DSM 7358 putative ADA-like regulatory protein YP_008739137.1 8522633 D 1246995 CDS YP_008739138.1 556570713 17448504 8524033..8524605 1 NC_022657.1 COG0350 Methylated DNA-protein cysteine methyltransferase; putative methylated-DNA--protein-cysteine S-methyltransferase 8524605 17448504 AFR_39155 Actinoplanes friuliensis DSM 7358 putative methylated-DNA--protein-cysteine S-methyltransferase YP_008739138.1 8524033 D 1246995 CDS YP_008739139.1 556570714 17448505 complement(8524545..8525045) 1 NC_022657.1 hypothetical protein 8525045 17448505 AFR_39160 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739139.1 8524545 R 1246995 CDS YP_008739140.1 556570715 17448506 complement(8525039..8531761) 1 NC_022657.1 COG3209 Rhs family protein; Rhs family protein-like protein 8531761 17448506 AFR_39165 Actinoplanes friuliensis DSM 7358 Rhs family protein-like protein YP_008739140.1 8525039 R 1246995 CDS YP_008739141.1 556570716 17448507 complement(8531827..8535495) 1 NC_022657.1 hypothetical protein 8535495 17448507 AFR_39170 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739141.1 8531827 R 1246995 CDS YP_008739142.1 556570717 17448508 8535697..8538198 1 NC_022657.1 COG0525 Valyl-tRNA synthetase; valyl-tRNA ligase 8538198 valS 17448508 valS Actinoplanes friuliensis DSM 7358 valyl-tRNA ligase YP_008739142.1 8535697 D 1246995 CDS YP_008739143.1 556570718 17448509 8538253..8538801 1 NC_022657.1 hypothetical protein 8538801 17448509 AFR_39180 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739143.1 8538253 D 1246995 CDS YP_008739144.1 556570719 17448510 complement(8538798..8539514) 1 NC_022657.1 hypothetical protein 8539514 17448510 AFR_39185 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739144.1 8538798 R 1246995 CDS YP_008739145.1 556570720 17448511 8539515..8540735 1 NC_022657.1 COG1322 Uncharacterized protein conserved in bacteria; hypothetical protein 8540735 17448511 AFR_39190 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739145.1 8539515 D 1246995 CDS YP_008739146.1 556570721 17448512 complement(8540732..8541793) 1 NC_022657.1 COG0761 Penicillin tolerance protein; 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 8541793 ispH 17448512 ispH Actinoplanes friuliensis DSM 7358 4-hydroxy-3-methylbut-2-enyl diphosphate reductase YP_008739146.1 8540732 R 1246995 CDS YP_008739147.1 556570722 17448513 8541835..8542341 1 NC_022657.1 hypothetical protein 8542341 17448513 AFR_39200 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739147.1 8541835 D 1246995 CDS YP_008739148.1 556570723 17448514 8542410..8542934 1 NC_022657.1 hypothetical protein 8542934 17448514 AFR_39205 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739148.1 8542410 D 1246995 CDS YP_008739149.1 556570724 17448515 8542955..8544172 1 NC_022657.1 COG1570 Exonuclease VII, large subunit; putative exoribonuclease large subunit 8544172 17448515 AFR_39210 Actinoplanes friuliensis DSM 7358 putative exoribonuclease large subunit YP_008739149.1 8542955 D 1246995 CDS YP_008739150.1 556570725 17448516 8544172..8544375 1 NC_022657.1 COG1722 Exonuclease VII small subunit; putative exoribonuclease small subunit 8544375 17448516 AFR_39215 Actinoplanes friuliensis DSM 7358 putative exoribonuclease small subunit YP_008739150.1 8544172 D 1246995 CDS YP_008739151.1 556570726 17448517 complement(8544372..8544923) 1 NC_022657.1 hypothetical protein 8544923 17448517 AFR_39220 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739151.1 8544372 R 1246995 CDS YP_008739152.1 556570727 17448518 8545020..8546045 1 NC_022657.1 COG1494 Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase and related proteins; fructose 1,6-bisphosphatase II 8546045 glpX 17448518 glpX Actinoplanes friuliensis DSM 7358 fructose 1,6-bisphosphatase II YP_008739152.1 8545020 D 1246995 CDS YP_008739153.1 556570728 17448519 8546042..8547043 1 NC_022657.1 COG3238 Uncharacterized protein conserved in bacteria; hypothetical protein 8547043 17448519 AFR_39230 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739153.1 8546042 D 1246995 CDS YP_008739154.1 556570729 17448520 complement(8547030..8547692) 1 NC_022657.1 COG0705 Uncharacterized membrane protein (homolog of Drosophila rhomboid); hypothetical protein 8547692 17448520 AFR_39235 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739154.1 8547030 R 1246995 CDS YP_008739155.1 556570730 17448521 complement(8547753..8548517) 1 NC_022657.1 COG5640 Secreted trypsin-like serine protease; Anionic trypsin-2 8548517 17448521 AFR_39240 Actinoplanes friuliensis DSM 7358 Anionic trypsin-2 YP_008739155.1 8547753 R 1246995 CDS YP_008739156.1 556570731 17448522 complement(8548623..8549342) 1 NC_022657.1 hypothetical protein 8549342 17448522 AFR_39245 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739156.1 8548623 R 1246995 CDS YP_008739157.1 556570732 17448523 complement(8549728..8551140) 1 NC_022657.1 COG1875 Predicted ATPase related to phosphate starvation-inducible protein PhoH; PhoH-like ATPase 8551140 17448523 AFR_39250 Actinoplanes friuliensis DSM 7358 PhoH-like ATPase YP_008739157.1 8549728 R 1246995 CDS YP_008739158.1 556570733 17448524 8551395..8552228 1 NC_022657.1 COG1877 Trehalose-6-phosphatase; trehalose-phosphatase 8552228 17448524 AFR_39255 Actinoplanes friuliensis DSM 7358 trehalose-phosphatase YP_008739158.1 8551395 D 1246995 CDS YP_008739159.1 556570734 17448525 complement(8552205..8553080) 1 NC_022657.1 COG0583 Transcriptional regulator; putative LysR-family transcriptional regulator 8553080 17448525 AFR_39260 Actinoplanes friuliensis DSM 7358 putative LysR-family transcriptional regulator YP_008739159.1 8552205 R 1246995 CDS YP_008739160.1 556570735 17448526 8553275..8554225 1 NC_022657.1 COG5006 Predicted permease, DMT superfamily; hypothetical protein 8554225 17448526 AFR_39265 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739160.1 8553275 D 1246995 CDS YP_008739161.1 556570736 17448527 complement(8554062..8554832) 1 NC_022657.1 COG0020 Undecaprenyl pyrophosphate synthase; putative undecaprenyl diphosphate synthase 8554832 17448527 AFR_39270 Actinoplanes friuliensis DSM 7358 putative undecaprenyl diphosphate synthase YP_008739161.1 8554062 R 1246995 CDS YP_008739162.1 556570737 17448528 complement(8554864..8555991) 1 NC_022657.1 COG0644 Dehydrogenases (flavoproteins); geranylgeranyl reductase 8555991 17448528 AFR_39275 Actinoplanes friuliensis DSM 7358 geranylgeranyl reductase YP_008739162.1 8554864 R 1246995 CDS YP_008739163.1 556570738 17448529 complement(8555988..8557046) 1 NC_022657.1 YadA domain-containing protein 8557046 17448529 AFR_39280 Actinoplanes friuliensis DSM 7358 YadA domain-containing protein YP_008739163.1 8555988 R 1246995 CDS YP_008739164.1 556570739 17448530 complement(8556995..8557846) 1 NC_022657.1 hypothetical protein 8557846 17448530 AFR_39285 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739164.1 8556995 R 1246995 CDS YP_008739165.1 556570740 17448531 complement(8557902..8559701) 1 NC_022657.1 COG1274 Phosphoenolpyruvate carboxykinase (GTP); phosphoenolpyruvate carboxykinase 8559701 17448531 AFR_39290 Actinoplanes friuliensis DSM 7358 phosphoenolpyruvate carboxykinase YP_008739165.1 8557902 R 1246995 CDS YP_008739166.1 556570741 17448532 8560018..8560809 1 NC_022657.1 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; RNA polymerase sigma factor ylaC 8560809 17448532 AFR_39295 Actinoplanes friuliensis DSM 7358 RNA polymerase sigma factor ylaC YP_008739166.1 8560018 D 1246995 CDS YP_008739167.1 556570742 17448533 8560806..8561396 1 NC_022657.1 COG2246 Predicted membrane protein; putative GtrA-like protein 8561396 17448533 AFR_39300 Actinoplanes friuliensis DSM 7358 putative GtrA-like protein YP_008739167.1 8560806 D 1246995 CDS YP_008739168.1 556570743 17448534 8561459..8562022 1 NC_022657.1 COG2246 Predicted membrane protein; putative GtrA-like protein 8562022 17448534 AFR_39305 Actinoplanes friuliensis DSM 7358 putative GtrA-like protein YP_008739168.1 8561459 D 1246995 CDS YP_008739169.1 556570744 17448535 complement(8561949..8562563) 1 NC_022657.1 COG3428 Predicted membrane protein; hypothetical protein 8562563 17448535 AFR_39310 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739169.1 8561949 R 1246995 CDS YP_008739170.1 556570745 17448536 complement(8562568..8563428) 1 NC_022657.1 COG0340 Biotin-(acetyl-CoA carboxylase) ligase; putative biotin apo-protein ligase 8563428 17448536 AFR_39315 Actinoplanes friuliensis DSM 7358 putative biotin apo-protein ligase YP_008739170.1 8562568 R 1246995 CDS YP_008739171.1 556570746 17448537 complement(8563461..8565152) 1 NC_022657.1 Halomucin 8565152 17448537 AFR_39320 Actinoplanes friuliensis DSM 7358 Halomucin YP_008739171.1 8563461 R 1246995 CDS YP_008739172.1 556570747 17448538 8566368..8567942 1 NC_022657.1 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta); putative acyl-CoA carboxylase subunit beta 8567942 17448538 AFR_39325 Actinoplanes friuliensis DSM 7358 putative acyl-CoA carboxylase subunit beta YP_008739172.1 8566368 D 1246995 CDS YP_008739173.1 556570748 17448539 complement(8567943..8568602) 1 NC_022657.1 hypothetical protein 8568602 17448539 AFR_39330 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739173.1 8567943 R 1246995 CDS YP_008739174.1 556570749 17448540 complement(8568681..8569421) 1 NC_022657.1 hypothetical protein 8569421 17448540 AFR_39335 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739174.1 8568681 R 1246995 CDS YP_008739175.1 556570750 17448541 complement(8569615..8569818) 1 NC_022657.1 hypothetical protein 8569818 17448541 AFR_39340 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739175.1 8569615 R 1246995 CDS YP_008739176.1 556570751 17448542 complement(8569881..8573297) 1 NC_022657.1 COG0515 Serine/threonine protein kinase; Serine/threonine protein kinase 8573297 17448542 AFR_39345 Actinoplanes friuliensis DSM 7358 Serine/threonine protein kinase YP_008739176.1 8569881 R 1246995 CDS YP_008739177.1 556570752 17448543 8573854..8574195 1 NC_022657.1 Duffy receptor gamma form 8574195 17448543 AFR_39350 Actinoplanes friuliensis DSM 7358 Duffy receptor gamma form YP_008739177.1 8573854 D 1246995 CDS YP_008739178.1 556570753 17448544 complement(8574491..8574739) 1 NC_022657.1 hypothetical protein 8574739 17448544 AFR_39355 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739178.1 8574491 R 1246995 CDS YP_008739179.1 556570754 17448545 8575610..8576737 1 NC_022657.1 COG1404 Subtilisin-like serine proteases; peptidase s8 and s53 subtilisin kexin sedolisin 8576737 17448545 AFR_39360 Actinoplanes friuliensis DSM 7358 peptidase s8 and s53 subtilisin kexin sedolisin YP_008739179.1 8575610 D 1246995 CDS YP_008739180.1 556570755 17448546 8576851..8577411 1 NC_022657.1 COG0424 Nucleotide-binding protein implicated in inhibition of septum formation; putative septum formation protein 8577411 17448546 AFR_39365 Actinoplanes friuliensis DSM 7358 putative septum formation protein YP_008739180.1 8576851 D 1246995 CDS YP_008739181.1 556570756 17448547 complement(8577408..8578163) 1 NC_022657.1 COG0842 ABC-type multidrug transport system, permease component; ABC transporter 8578163 17448547 AFR_39370 Actinoplanes friuliensis DSM 7358 ABC transporter YP_008739181.1 8577408 R 1246995 CDS YP_008739182.1 556570757 17448548 complement(8578167..8579117) 1 NC_022657.1 COG1131 ABC-type multidrug transport system, ATPase component; daunorubicin resistance ABC transporter ATPase subunit 8579117 17448548 AFR_39375 Actinoplanes friuliensis DSM 7358 daunorubicin resistance ABC transporter ATPase subunit YP_008739182.1 8578167 R 1246995 CDS YP_008739183.1 556570758 17448549 complement(8579207..8579791) 1 NC_022657.1 COG1695 Predicted transcriptional regulators; PadR family transcriptional regulator 8579791 17448549 AFR_39380 Actinoplanes friuliensis DSM 7358 PadR family transcriptional regulator YP_008739183.1 8579207 R 1246995 CDS YP_008739184.1 556570759 17448550 8579871..8581616 1 NC_022657.1 COG4770 Acetyl/propionyl-CoA carboxylase, alpha subunit; putative acyl-CoA carboxylase subunit alpha 8581616 17448550 AFR_39385 Actinoplanes friuliensis DSM 7358 putative acyl-CoA carboxylase subunit alpha YP_008739184.1 8579871 D 1246995 CDS YP_008739185.1 556570760 17448551 complement(8582407..8582979) 1 NC_022657.1 COG1309 Transcriptional regulator; HTH-type transcriptional regulator betI 8582979 17448551 AFR_39390 Actinoplanes friuliensis DSM 7358 HTH-type transcriptional regulator betI YP_008739185.1 8582407 R 1246995 CDS YP_008739186.1 556570761 17448552 8583056..8583499 1 NC_022657.1 COG4270 Predicted membrane protein; DoxX family protein 8583499 17448552 AFR_39395 Actinoplanes friuliensis DSM 7358 DoxX family protein YP_008739186.1 8583056 D 1246995 CDS YP_008739187.1 556570762 17448553 complement(8584001..8584873) 1 NC_022657.1 COG1305 Transglutaminase-like enzymes, putative cysteine proteases; transglutaminase 8584873 17448553 AFR_39400 Actinoplanes friuliensis DSM 7358 transglutaminase YP_008739187.1 8584001 R 1246995 CDS YP_008739188.1 556570763 17448554 complement(8584870..8585811) 1 NC_022657.1 COG2307 Uncharacterized protein conserved in bacteria; hypothetical protein 8585811 17448554 AFR_39405 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739188.1 8584870 R 1246995 CDS YP_008739189.1 556570764 17448555 complement(8585805..8587388) 1 NC_022657.1 COG2308 Uncharacterized conserved protein; hypothetical protein 8587388 17448555 AFR_39410 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739189.1 8585805 R 1246995 CDS YP_008739190.1 556570765 17448556 8587807..8588523 1 NC_022657.1 COG0586 Uncharacterized membrane-associated protein; hypothetical protein 8588523 17448556 AFR_39415 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739190.1 8587807 D 1246995 CDS YP_008739191.1 556570766 17448557 complement(8588551..8589951) 1 NC_022657.1 COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes; flavoprotein disulfide reductase 8589951 17448557 AFR_39420 Actinoplanes friuliensis DSM 7358 flavoprotein disulfide reductase YP_008739191.1 8588551 R 1246995 CDS YP_008739192.1 556570767 17448558 8590059..8590520 1 NC_022657.1 hypothetical protein 8590520 17448558 AFR_39425 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739192.1 8590059 D 1246995 CDS YP_008739193.1 556570768 17448559 complement(8590484..8591470) 1 NC_022657.1 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; N-acetyltransferase GCN5 8591470 17448559 AFR_39430 Actinoplanes friuliensis DSM 7358 N-acetyltransferase GCN5 YP_008739193.1 8590484 R 1246995 CDS YP_008739194.1 556570769 17448560 complement(8591514..8592251) 1 NC_022657.1 hypothetical protein 8592251 17448560 AFR_39435 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739194.1 8591514 R 1246995 CDS YP_008739195.1 556570770 17448561 complement(8592294..8593211) 1 NC_022657.1 hypothetical protein 8593211 17448561 AFR_39440 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739195.1 8592294 R 1246995 CDS YP_008739196.1 556570771 17448562 complement(8593213..8593848) 1 NC_022657.1 COG2220 Predicted Zn-dependent hydrolases of the beta-lactamase fold; beta-lactamase domain-containing protein 8593848 17448562 AFR_39445 Actinoplanes friuliensis DSM 7358 beta-lactamase domain-containing protein YP_008739196.1 8593213 R 1246995 CDS YP_008739197.1 556570772 17448563 8594009..8595118 1 NC_022657.1 hypothetical protein 8595118 17448563 AFR_39450 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739197.1 8594009 D 1246995 CDS YP_008739198.1 556570773 17448564 complement(8595301..8596548) 1 NC_022657.1 COG1473 Metal-dependent amidase/aminoacylase/carboxypeptidase; amidohydrolase 8596548 17448564 AFR_39455 Actinoplanes friuliensis DSM 7358 amidohydrolase YP_008739198.1 8595301 R 1246995 CDS YP_008739199.1 556570774 17448565 complement(8596789..8598360) 1 NC_022657.1 COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit; putative methylmalonyl-CoA mutase subunit alpha 8598360 17448565 AFR_39460 Actinoplanes friuliensis DSM 7358 putative methylmalonyl-CoA mutase subunit alpha YP_008739199.1 8596789 R 1246995 CDS YP_008739200.1 556570775 17448566 8598659..8600557 1 NC_022657.1 COG0515 Serine/threonine protein kinase; putative serine/threonine protein kinase 8600557 17448566 AFR_39465 Actinoplanes friuliensis DSM 7358 putative serine/threonine protein kinase YP_008739200.1 8598659 D 1246995 CDS YP_008739201.1 556570776 17448567 8600585..8602234 1 NC_022657.1 COG1109 Phosphomannomutase; putative phosphomannomutase 8602234 17448567 AFR_39470 Actinoplanes friuliensis DSM 7358 putative phosphomannomutase YP_008739201.1 8600585 D 1246995 CDS YP_008739202.1 556570777 17448568 complement(8602257..8602940) 1 NC_022657.1 hypothetical protein 8602940 17448568 AFR_39475 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739202.1 8602257 R 1246995 CDS YP_008739203.1 556570778 17448569 complement(8602999..8603970) 1 NC_022657.1 hypothetical protein 8603970 17448569 AFR_39480 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739203.1 8602999 R 1246995 CDS YP_008739204.1 556570779 17448570 complement(8603967..8607464) 1 NC_022657.1 COG0463 Glycosyltransferases involved in cell wall biogenesis; putative CDP-glycerol--polyglycerol phosphate glycero-phosphotransferase 8607464 17448570 AFR_39485 Actinoplanes friuliensis DSM 7358 putative CDP-glycerol--polyglycerol phosphate glycero-phosphotransferase YP_008739204.1 8603967 R 1246995 CDS YP_008739205.1 556570780 17448571 8607551..8608033 1 NC_022657.1 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; putative NUDIX hydrolase 8608033 17448571 AFR_39490 Actinoplanes friuliensis DSM 7358 putative NUDIX hydrolase YP_008739205.1 8607551 D 1246995 CDS YP_008739206.1 556570781 17448572 complement(8608030..8608662) 1 NC_022657.1 COG0035 Uracil phosphoribosyltransferase; uracil phosphoribosyltransferase 8608662 17448572 AFR_39495 Actinoplanes friuliensis DSM 7358 uracil phosphoribosyltransferase YP_008739206.1 8608030 R 1246995 CDS YP_008739207.1 556570782 17448573 8608725..8609675 1 NC_022657.1 COG0274 Deoxyribose-phosphate aldolase; deoxyribose-phosphate aldolase 8609675 17448573 AFR_39500 Actinoplanes friuliensis DSM 7358 deoxyribose-phosphate aldolase YP_008739207.1 8608725 D 1246995 CDS YP_008739208.1 556570783 17448574 8609680..8611107 1 NC_022657.1 COG1012 NAD-dependent aldehyde dehydrogenases; putative aldehyde dehydrogenase 8611107 17448574 AFR_39505 Actinoplanes friuliensis DSM 7358 putative aldehyde dehydrogenase YP_008739208.1 8609680 D 1246995 CDS YP_008739209.1 556570784 17448575 8611100..8611954 1 NC_022657.1 COG1012 NAD-dependent aldehyde dehydrogenases; putative aldehyde dehydrogenase 8611954 17448575 AFR_39510 Actinoplanes friuliensis DSM 7358 putative aldehyde dehydrogenase YP_008739209.1 8611100 D 1246995 CDS YP_008739210.1 556570785 17448576 8612047..8612964 1 NC_022657.1 hypothetical protein 8612964 17448576 AFR_39515 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739210.1 8612047 D 1246995 CDS YP_008739211.1 556570786 17448577 8613028..8615277 1 NC_022657.1 hypothetical protein 8615277 17448577 AFR_39520 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739211.1 8613028 D 1246995 CDS YP_008739212.1 556570787 17448578 complement(8616281..8616799) 1 NC_022657.1 hypothetical protein 8616799 17448578 AFR_39525 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739212.1 8616281 R 1246995 CDS YP_008739213.1 556570788 17448579 complement(8617334..8617921) 1 NC_022657.1 COG2229 Predicted GTPase; putative ATP/GTP-binding protein 8617921 17448579 AFR_39530 Actinoplanes friuliensis DSM 7358 putative ATP/GTP-binding protein YP_008739213.1 8617334 R 1246995 CDS YP_008739214.1 556570789 17448580 complement(8617923..8618303) 1 NC_022657.1 hypothetical protein 8618303 17448580 AFR_39535 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739214.1 8617923 R 1246995 CDS YP_008739215.1 556570790 17448581 complement(8618390..8618794) 1 NC_022657.1 COG2018 Uncharacterized distant relative of homeotic protein bithoraxoid; hypothetical protein 8618794 17448581 AFR_39540 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739215.1 8618390 R 1246995 CDS YP_008739216.1 556570791 17448582 complement(8618791..8622465) 1 NC_022657.1 COG0642 Signal transduction histidine kinase; putative sensor-like histidine kinase 8622465 17448582 AFR_39545 Actinoplanes friuliensis DSM 7358 putative sensor-like histidine kinase YP_008739216.1 8618791 R 1246995 CDS YP_008739217.1 556570792 17448583 complement(8622911..8623978) 1 NC_022657.1 COG1816 Adenosine deaminase; adenosine deaminase 8623978 17448583 AFR_39550 Actinoplanes friuliensis DSM 7358 adenosine deaminase YP_008739217.1 8622911 R 1246995 CDS YP_008739218.1 556570793 17448584 8624005..8624814 1 NC_022657.1 COG0500 SAM-dependent methyltransferases; putative rRNA methyltransferase 8624814 17448584 AFR_39555 Actinoplanes friuliensis DSM 7358 putative rRNA methyltransferase YP_008739218.1 8624005 D 1246995 CDS YP_008739219.1 556570794 17448585 complement(8624916..8625593) 1 NC_022657.1 hypothetical protein 8625593 17448585 AFR_39560 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739219.1 8624916 R 1246995 CDS YP_008739220.1 556570795 17448586 complement(8625600..8626877) 1 NC_022657.1 COG0213 Thymidine phosphorylase; thymidine phosphorylase 8626877 deoA 17448586 deoA Actinoplanes friuliensis DSM 7358 thymidine phosphorylase YP_008739220.1 8625600 R 1246995 CDS YP_008739221.1 556570796 17448587 complement(8626874..8627587) 1 NC_022657.1 COG0295 Cytidine deaminase; cytidine deaminase 8627587 17448587 AFR_39570 Actinoplanes friuliensis DSM 7358 cytidine deaminase YP_008739221.1 8626874 R 1246995 CDS YP_008739222.1 556570797 17448588 complement(8627632..8628909) 1 NC_022657.1 COG1079 Uncharacterized ABC-type transport system, permease component; putative sugar ABC transporter permease 8628909 17448588 AFR_39575 Actinoplanes friuliensis DSM 7358 putative sugar ABC transporter permease YP_008739222.1 8627632 R 1246995 CDS YP_008739223.1 556570798 17448589 complement(8628906..8630198) 1 NC_022657.1 COG4603 ABC-type uncharacterized transport system, permease component; putative sugar ABC transporter permease 8630198 17448589 AFR_39580 Actinoplanes friuliensis DSM 7358 putative sugar ABC transporter permease YP_008739223.1 8628906 R 1246995 CDS YP_008739224.1 556570799 17448590 complement(8630195..8631742) 1 NC_022657.1 COG3845 ABC-type uncharacterized transport systems, ATPase components; ABC transporter 8631742 17448590 AFR_39585 Actinoplanes friuliensis DSM 7358 ABC transporter YP_008739224.1 8630195 R 1246995 CDS YP_008739225.1 556570800 17448591 complement(8631916..8632869) 1 NC_022657.1 COG1744 Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein; putative membrane lipoprotein 8632869 17448591 AFR_39590 Actinoplanes friuliensis DSM 7358 putative membrane lipoprotein YP_008739225.1 8631916 R 1246995 CDS YP_008739226.1 556570801 17448592 complement(8633206..8633520) 1 NC_022657.1 hypothetical protein 8633520 17448592 AFR_39595 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739226.1 8633206 R 1246995 CDS YP_008739227.1 556570802 17448593 complement(8633540..8634514) 1 NC_022657.1 hypothetical protein 8634514 17448593 AFR_39600 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739227.1 8633540 R 1246995 CDS YP_008739228.1 556570803 17448594 8634615..8635199 1 NC_022657.1 COG1309 Transcriptional regulator; HTH-type transcriptional regulator betI 8635199 17448594 AFR_39605 Actinoplanes friuliensis DSM 7358 HTH-type transcriptional regulator betI YP_008739228.1 8634615 D 1246995 CDS YP_008739229.1 556570804 17448595 complement(8635185..8635580) 1 NC_022657.1 hypothetical protein 8635580 17448595 AFR_39610 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739229.1 8635185 R 1246995 CDS YP_008739230.1 556570805 17448596 complement(8635588..8636526) 1 NC_022657.1 COG1295 Predicted membrane protein; hypothetical protein 8636526 17448596 AFR_39615 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739230.1 8635588 R 1246995 CDS YP_008739231.1 556570806 17448597 complement(8636594..8637127) 1 NC_022657.1 COG1514 2'-5' RNA ligase; putative 2',5' RNA ligase 8637127 17448597 AFR_39620 Actinoplanes friuliensis DSM 7358 putative 2',5' RNA ligase YP_008739231.1 8636594 R 1246995 CDS YP_008739232.1 556570807 17448598 complement(8637133..8638158) 1 NC_022657.1 COG0180 Tryptophanyl-tRNA synthetase; tryptophanyl-tRNA ligase 8638158 17448598 AFR_39625 Actinoplanes friuliensis DSM 7358 tryptophanyl-tRNA ligase YP_008739232.1 8637133 R 1246995 CDS YP_008739233.1 556570808 17448599 8638311..8639288 1 NC_022657.1 COG1087 UDP-glucose 4-epimerase; putative UDP-glucose 4-epimerase 8639288 17448599 AFR_39630 Actinoplanes friuliensis DSM 7358 putative UDP-glucose 4-epimerase YP_008739233.1 8638311 D 1246995 CDS YP_008739234.1 556570809 17448600 8639302..8640438 1 NC_022657.1 COG0153 Galactokinase; putative galactokinase 8640438 17448600 AFR_39635 Actinoplanes friuliensis DSM 7358 putative galactokinase YP_008739234.1 8639302 D 1246995 CDS YP_008739235.1 556570810 17448601 complement(8640435..8640914) 1 NC_022657.1 activator of Hsp90 ATPase 1 family protein 8640914 17448601 AFR_39640 Actinoplanes friuliensis DSM 7358 activator of Hsp90 ATPase 1 family protein YP_008739235.1 8640435 R 1246995 CDS YP_008739236.1 556570811 17448602 complement(8640911..8641234) 1 NC_022657.1 COG0640 Predicted transcriptional regulators; ArsR family transcriptional regulator 8641234 17448602 AFR_39645 Actinoplanes friuliensis DSM 7358 ArsR family transcriptional regulator YP_008739236.1 8640911 R 1246995 CDS YP_008739237.1 556570812 17448603 8641289..8641486 1 NC_022657.1 hypothetical protein 8641486 17448603 AFR_39650 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739237.1 8641289 D 1246995 CDS YP_008739238.1 556570813 17448604 complement(8641489..8642400) 1 NC_022657.1 COG3507 Beta-xylosidase; glycoside hydrolase family protein 8642400 17448604 AFR_39655 Actinoplanes friuliensis DSM 7358 glycoside hydrolase family protein YP_008739238.1 8641489 R 1246995 CDS YP_008739239.1 556570814 17448605 complement(8642505..8644640) 1 NC_022657.1 COG3507 Beta-xylosidase; glycoside hydrolase family 43 protein 8644640 17448605 AFR_39660 Actinoplanes friuliensis DSM 7358 glycoside hydrolase family 43 protein YP_008739239.1 8642505 R 1246995 CDS YP_008739240.1 556570815 17448606 complement(8644645..8645472) 1 NC_022657.1 COG0395 ABC-type sugar transport system, permease component; ABC transporter permease 8645472 17448606 AFR_39665 Actinoplanes friuliensis DSM 7358 ABC transporter permease YP_008739240.1 8644645 R 1246995 CDS YP_008739241.1 556570816 17448607 complement(8645475..8646425) 1 NC_022657.1 COG1175 ABC-type sugar transport systems, permease components; ABC transporter permease 8646425 17448607 AFR_39670 Actinoplanes friuliensis DSM 7358 ABC transporter permease YP_008739241.1 8645475 R 1246995 CDS YP_008739242.1 556570817 17448608 complement(8646431..8647765) 1 NC_022657.1 COG1653 ABC-type sugar transport system, periplasmic component; putative ABC transporter substrate-binding protein 8647765 17448608 AFR_39675 Actinoplanes friuliensis DSM 7358 putative ABC transporter substrate-binding protein YP_008739242.1 8646431 R 1246995 CDS YP_008739243.1 556570818 17448609 complement(8647762..8649273) 1 NC_022657.1 COG3534 Alpha-L-arabinofuranosidase; putative alpha-L-arabinofuranosidase 8649273 17448609 AFR_39680 Actinoplanes friuliensis DSM 7358 putative alpha-L-arabinofuranosidase YP_008739243.1 8647762 R 1246995 CDS YP_008739244.1 556570819 17448610 complement(8649390..8650367) 1 NC_022657.1 COG1609 Transcriptional regulators; putative LacI-family transcriptional regulator 8650367 17448610 AFR_39685 Actinoplanes friuliensis DSM 7358 putative LacI-family transcriptional regulator YP_008739244.1 8649390 R 1246995 CDS YP_008739245.1 556570820 17448611 complement(8650525..8651823) 1 NC_022657.1 COG2895 GTPases - Sulfate adenylate transferase subunit 1; putative sulfate adenylyltransferase subunit 1 8651823 17448611 AFR_39690 Actinoplanes friuliensis DSM 7358 putative sulfate adenylyltransferase subunit 1 YP_008739245.1 8650525 R 1246995 CDS YP_008739246.1 556570821 17448612 complement(8651823..8652734) 1 NC_022657.1 COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes; sulfate adenylyltransferase subunit 2 8652734 17448612 AFR_39695 Actinoplanes friuliensis DSM 7358 sulfate adenylyltransferase subunit 2 YP_008739246.1 8651823 R 1246995 CDS YP_008739247.1 556570822 17448613 complement(8652782..8653666) 1 NC_022657.1 COG1218 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase; putative inositol monophosphatase 8653666 17448613 AFR_39700 Actinoplanes friuliensis DSM 7358 putative inositol monophosphatase YP_008739247.1 8652782 R 1246995 CDS YP_008739248.1 556570823 17448614 complement(8653708..8655507) 1 NC_022657.1 COG2148 Sugar transferases involved in lipopolysaccharide synthesis; putative glycosyltransferase 8655507 17448614 AFR_39705 Actinoplanes friuliensis DSM 7358 putative glycosyltransferase YP_008739248.1 8653708 R 1246995 CDS YP_008739249.1 556570824 17448615 complement(8655647..8656234) 1 NC_022657.1 COG0193 Peptidyl-tRNA hydrolase; putative peptidyl-tRNA hydrolase 8656234 17448615 AFR_39710 Actinoplanes friuliensis DSM 7358 putative peptidyl-tRNA hydrolase YP_008739249.1 8655647 R 1246995 CDS YP_008739250.1 556570825 17448616 complement(8656304..8656936) 1 NC_022657.1 COG1825 Ribosomal protein L25 (general stress protein Ctc); 50S ribosomal protein L25/general stress protein Ctc 8656936 17448616 AFR_39715 Actinoplanes friuliensis DSM 7358 50S ribosomal protein L25/general stress protein Ctc YP_008739250.1 8656304 R 1246995 CDS YP_008739251.1 556570826 17448617 complement(8657232..8658212) 1 NC_022657.1 COG0462 Phosphoribosylpyrophosphate synthetase; ribose-phosphate pyrophosphokinase 8658212 17448617 AFR_39720 Actinoplanes friuliensis DSM 7358 ribose-phosphate pyrophosphokinase YP_008739251.1 8657232 R 1246995 CDS YP_008739252.1 556570827 17448618 complement(8658328..8659776) 1 NC_022657.1 COG1207 N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains); putative UDP-N-acetylglucosamine pyrophosphorylase 8659776 17448618 AFR_39725 Actinoplanes friuliensis DSM 7358 putative UDP-N-acetylglucosamine pyrophosphorylase YP_008739252.1 8658328 R 1246995 CDS YP_008739253.1 556570828 17448620 complement(8660101..8661048) 1 NC_022657.1 COG3509 Poly(3-hydroxybutyrate) depolymerase; polyhydroxybutyrate depolymerase 8661048 17448620 AFR_39730 Actinoplanes friuliensis DSM 7358 polyhydroxybutyrate depolymerase YP_008739253.1 8660101 R 1246995 CDS YP_008739254.1 556570829 17448621 complement(8661079..8662746) 1 NC_022657.1 hypothetical protein 8662746 17448621 AFR_39735 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739254.1 8661079 R 1246995 CDS YP_008739255.1 556570830 17448622 complement(8662898..8664571) 1 NC_022657.1 hypothetical protein 8664571 17448622 AFR_39740 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739255.1 8662898 R 1246995 CDS YP_008739256.1 556570831 17448623 complement(8664604..8665533) 1 NC_022657.1 methyltransferase 8665533 17448623 AFR_39745 Actinoplanes friuliensis DSM 7358 methyltransferase YP_008739256.1 8664604 R 1246995 CDS YP_008739257.1 556570832 17448624 complement(8665548..8666312) 1 NC_022657.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); alpha/beta hydrolase 8666312 17448624 AFR_39750 Actinoplanes friuliensis DSM 7358 alpha/beta hydrolase YP_008739257.1 8665548 R 1246995 CDS YP_008739258.1 556570833 17448625 complement(8666309..8666611) 1 NC_022657.1 COG0236 Acyl carrier protein; acyl carrier protein 8666611 17448625 AFR_39755 Actinoplanes friuliensis DSM 7358 acyl carrier protein YP_008739258.1 8666309 R 1246995 CDS YP_008739259.1 556570834 17448626 complement(8666623..8671632) 1 NC_022657.1 COG3321 Polyketide synthase modules and related proteins; beta-ketoacyl synthase 8671632 17448626 AFR_39760 Actinoplanes friuliensis DSM 7358 beta-ketoacyl synthase YP_008739259.1 8666623 R 1246995 CDS YP_008739260.1 556570835 17448627 complement(8671638..8678696) 1 NC_022657.1 COG2070 Dioxygenases related to 2-nitropropane dioxygenase; modular polyketide synthase 8678696 17448627 AFR_39765 Actinoplanes friuliensis DSM 7358 modular polyketide synthase YP_008739260.1 8671638 R 1246995 CDS YP_008739261.1 556570836 17448628 8678979..8679674 1 NC_022657.1 COG1309 Transcriptional regulator; TetR family transcriptional regulator 8679674 17448628 AFR_39770 Actinoplanes friuliensis DSM 7358 TetR family transcriptional regulator YP_008739261.1 8678979 D 1246995 CDS YP_008739262.1 556570837 17448629 complement(8679719..8680177) 1 NC_022657.1 hypothetical protein 8680177 17448629 AFR_39775 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739262.1 8679719 R 1246995 CDS YP_008739263.1 556570838 17448630 complement(8680177..8680644) 1 NC_022657.1 hypothetical protein 8680644 17448630 AFR_39780 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739263.1 8680177 R 1246995 CDS YP_008739264.1 556570839 17448631 complement(8680721..8682526) 1 NC_022657.1 COG0488 ATPase components of ABC transporters with duplicated ATPase domains; ABC transporter 8682526 17448631 AFR_39785 Actinoplanes friuliensis DSM 7358 ABC transporter YP_008739264.1 8680721 R 1246995 CDS YP_008739265.1 556570840 17448632 complement(8682535..8683482) 1 NC_022657.1 COG1947 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase 8683482 17448632 AFR_39790 Actinoplanes friuliensis DSM 7358 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase YP_008739265.1 8682535 R 1246995 CDS YP_008739266.1 556570841 17448633 complement(8683479..8684054) 1 NC_022657.1 COG4636 Uncharacterized protein conserved in cyanobacteria; hypothetical protein 8684054 17448633 AFR_39795 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739266.1 8683479 R 1246995 CDS YP_008739267.1 556570842 17448634 complement(8684051..8685034) 1 NC_022657.1 COG0030 Dimethyladenosine transferase (rRNA methylation); 16S ribosomal RNA methyltransferase KsgA/Dim1 family protein 8685034 ksgA 17448634 ksgA Actinoplanes friuliensis DSM 7358 16S ribosomal RNA methyltransferase KsgA/Dim1 family protein YP_008739267.1 8684051 R 1246995 CDS YP_008739268.1 556570843 17448635 8685033..8685452 1 NC_022657.1 hypothetical protein 8685452 17448635 AFR_39805 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739268.1 8685033 D 1246995 CDS YP_008739269.1 556570844 17448636 complement(8685437..8686345) 1 NC_022657.1 COG0084 Mg-dependent DNase; TatD DNase family protein 8686345 17448636 AFR_39810 Actinoplanes friuliensis DSM 7358 TatD DNase family protein YP_008739269.1 8685437 R 1246995 CDS YP_008739270.1 556570845 17448637 8686448..8687482 1 NC_022657.1 hypothetical protein 8687482 17448637 AFR_39815 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739270.1 8686448 D 1246995 CDS YP_008739271.1 556570846 17448638 complement(8687541..8688848) 1 NC_022657.1 COG3291 FOG: PKD repeat; hypothetical protein 8688848 17448638 AFR_39820 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739271.1 8687541 R 1246995 CDS YP_008739272.1 556570847 17448639 complement(8689032..8690828) 1 NC_022657.1 COG0143 Methionyl-tRNA synthetase; methionyl-tRNA ligase 8690828 17448639 AFR_39825 Actinoplanes friuliensis DSM 7358 methionyl-tRNA ligase YP_008739272.1 8689032 R 1246995 CDS YP_008739273.1 556570848 17448640 8690939..8692204 1 NC_022657.1 hypothetical protein 8692204 17448640 AFR_39830 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739273.1 8690939 D 1246995 CDS YP_008739274.1 556570849 17448641 complement(8692198..8693046) 1 NC_022657.1 COG0313 Predicted methyltransferases; uroporphyrin-III C/tetrapyrrole methyltransferase 8693046 17448641 AFR_39835 Actinoplanes friuliensis DSM 7358 uroporphyrin-III C/tetrapyrrole methyltransferase YP_008739274.1 8692198 R 1246995 CDS YP_008739275.1 556570850 17448642 8693156..8694745 1 NC_022657.1 COG1928 Dolichyl-phosphate-mannose--protein O-mannosyl transferase; hypothetical protein 8694745 17448642 AFR_39840 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739275.1 8693156 D 1246995 CDS YP_008739276.1 556570851 17448643 8695328..8696197 1 NC_022657.1 filamentous hemagglutinin 8696197 17448643 AFR_39845 Actinoplanes friuliensis DSM 7358 filamentous hemagglutinin YP_008739276.1 8695328 D 1246995 CDS YP_008739277.1 556570852 17448644 8696194..8698635 1 NC_022657.1 COG0726 Predicted xylanase/chitin deacetylase; putative bifunctional glycosyltransferase/polysaccharide deacetylase 8698635 17448644 AFR_39850 Actinoplanes friuliensis DSM 7358 putative bifunctional glycosyltransferase/polysaccharide deacetylase YP_008739277.1 8696194 D 1246995 CDS YP_008739278.1 556570853 17448645 complement(8698683..8699906) 1 NC_022657.1 COG2203 FOG: GAF domain; putative GAF-sensor signal transduction histidine kinase 8699906 17448645 AFR_39855 Actinoplanes friuliensis DSM 7358 putative GAF-sensor signal transduction histidine kinase YP_008739278.1 8698683 R 1246995 CDS YP_008739279.1 556570854 17448646 complement(8699988..8700353) 1 NC_022657.1 COG0346 Lactoylglutathione lyase and related lyases; Glyoxalase/bleomycin resistance protein/dioxygenase 8700353 17448646 AFR_39860 Actinoplanes friuliensis DSM 7358 Glyoxalase/bleomycin resistance protein/dioxygenase YP_008739279.1 8699988 R 1246995 CDS YP_008739280.1 556570855 17448647 complement(8700431..8701192) 1 NC_022657.1 COG1409 Predicted phosphohydrolases; metallophosphoesterase 8701192 17448647 AFR_39865 Actinoplanes friuliensis DSM 7358 metallophosphoesterase YP_008739280.1 8700431 R 1246995 CDS YP_008739281.1 556570856 17448648 complement(8701267..8701623) 1 NC_022657.1 hypothetical protein 8701623 17448648 AFR_39870 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739281.1 8701267 R 1246995 CDS YP_008739282.1 556570857 17448649 complement(8701694..8702266) 1 NC_022657.1 COG0262 Dihydrofolate reductase; hypothetical protein 8702266 17448649 AFR_39875 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739282.1 8701694 R 1246995 CDS YP_008739283.1 556570858 17448650 complement(8702279..8702905) 1 NC_022657.1 hypothetical protein 8702905 17448650 AFR_39880 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739283.1 8702279 R 1246995 CDS YP_008739284.1 556570859 17448652 complement(8703086..8703868) 1 NC_022657.1 hypothetical protein 8703868 17448652 AFR_39885 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739284.1 8703086 R 1246995 CDS YP_008739285.1 556570860 17448653 complement(8704010..8704648) 1 NC_022657.1 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins; ribosomal-protein-alanine N-acetyltransferase 8704648 17448653 AFR_39890 Actinoplanes friuliensis DSM 7358 ribosomal-protein-alanine N-acetyltransferase YP_008739285.1 8704010 R 1246995 CDS YP_008739286.1 556570861 17448654 complement(8704648..8705958) 1 NC_022657.1 COG0303 Molybdopterin biosynthesis enzyme; putative molybdopterin biosynthesis protein A 8705958 17448654 AFR_39895 Actinoplanes friuliensis DSM 7358 putative molybdopterin biosynthesis protein A YP_008739286.1 8704648 R 1246995 CDS YP_008739287.1 556570862 17448655 complement(8705955..8706833) 1 NC_022657.1 COG1210 UDP-glucose pyrophosphorylase; UTP-glucose-1-phosphate uridylyltransferase 8706833 17448655 AFR_39900 Actinoplanes friuliensis DSM 7358 UTP-glucose-1-phosphate uridylyltransferase YP_008739287.1 8705955 R 1246995 CDS YP_008739288.1 556570863 17448656 complement(8706921..8708996) 1 NC_022657.1 COG2199 FOG: GGDEF domain; putative diguanylate cyclase with GAF sensor 8708996 17448656 AFR_39905 Actinoplanes friuliensis DSM 7358 putative diguanylate cyclase with GAF sensor YP_008739288.1 8706921 R 1246995 CDS YP_008739289.1 556570864 17448657 8709111..8709716 1 NC_022657.1 COG0212 5-formyltetrahydrofolate cyclo-ligase; 5-formyltetrahydrofolate cyclo-ligase 8709716 17448657 AFR_39910 Actinoplanes friuliensis DSM 7358 5-formyltetrahydrofolate cyclo-ligase YP_008739289.1 8709111 D 1246995 CDS YP_008739290.1 556570865 17448658 8709787..8710149 1 NC_022657.1 COG2331 Uncharacterized protein conserved in bacteria; putative regulatory protein 8710149 17448658 AFR_39915 Actinoplanes friuliensis DSM 7358 putative regulatory protein YP_008739290.1 8709787 D 1246995 CDS YP_008739291.1 556570866 17448659 8710559..8710801 1 NC_022657.1 hypothetical protein 8710801 17448659 AFR_39920 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739291.1 8710559 D 1246995 CDS YP_008739292.1 556570867 17448660 complement(8710808..8710990) 1 NC_022657.1 hypothetical protein 8710990 17448660 AFR_39925 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739292.1 8710808 R 1246995 CDS YP_008739293.1 556570868 17448661 8711049..8711381 1 NC_022657.1 hypothetical protein 8711381 17448661 AFR_39930 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739293.1 8711049 D 1246995 CDS YP_008739294.1 556570869 17448662 complement(8711427..8711906) 1 NC_022657.1 hypothetical protein 8711906 17448662 AFR_39935 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739294.1 8711427 R 1246995 CDS YP_008739295.1 556570870 17448663 8712111..8712545 1 NC_022657.1 COG0735 Fe2+/Zn2+ uptake regulation proteins; ferric uptake regulator family protein 8712545 17448663 AFR_39940 Actinoplanes friuliensis DSM 7358 ferric uptake regulator family protein YP_008739295.1 8712111 D 1246995 CDS YP_008739296.1 556570871 17448664 8712591..8713433 1 NC_022657.1 COG3662 Uncharacterized protein conserved in bacteria; hypothetical protein 8713433 17448664 AFR_39945 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739296.1 8712591 D 1246995 CDS YP_008739297.1 556570872 17448665 complement(8714068..8714850) 1 NC_022657.1 transposase is4 family protein 8714850 17448665 AFR_39950 Actinoplanes friuliensis DSM 7358 transposase is4 family protein YP_008739297.1 8714068 R 1246995 CDS YP_008739298.1 556570873 17448666 complement(8715465..8716355) 1 NC_022657.1 COG2887 RecB family exonuclease; hypothetical protein 8716355 17448666 AFR_39955 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739298.1 8715465 R 1246995 CDS YP_008739299.1 556570874 17448667 complement(8716388..8717005) 1 NC_022657.1 COG2095 Multiple antibiotic transporter; hypothetical protein 8717005 17448667 AFR_39960 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739299.1 8716388 R 1246995 CDS YP_008739300.1 556570875 17448668 complement(8717057..8717908) 1 NC_022657.1 COG0613 Predicted metal-dependent phosphoesterases (PHP family); hypothetical protein 8717908 17448668 AFR_39965 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739300.1 8717057 R 1246995 CDS YP_008739301.1 556570876 17448669 complement(8717953..8718720) 1 NC_022657.1 COG3428 Predicted membrane protein; hypothetical protein 8718720 17448669 AFR_39970 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739301.1 8717953 R 1246995 CDS YP_008739302.1 556570877 17448670 complement(8718853..8719011) 1 NC_022657.1 hypothetical protein 8719011 17448670 AFR_39975 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739302.1 8718853 R 1246995 CDS YP_008739303.1 556570878 17448671 complement(8719142..8719714) 1 NC_022657.1 hypothetical protein 8719714 17448671 AFR_39980 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739303.1 8719142 R 1246995 CDS YP_008739304.1 556570879 17448672 complement(8719903..8720565) 1 NC_022657.1 COG0566 rRNA methylases; putative RNA methyltransferase 8720565 17448672 AFR_39985 Actinoplanes friuliensis DSM 7358 putative RNA methyltransferase YP_008739304.1 8719903 R 1246995 CDS YP_008739305.1 556570880 17448673 8721032..8721394 1 NC_022657.1 COG0526 Thiol-disulfide isomerase and thioredoxins; putative thioredoxin 8721394 17448673 AFR_39990 Actinoplanes friuliensis DSM 7358 putative thioredoxin YP_008739305.1 8721032 D 1246995 CDS YP_008739306.1 556570881 17448674 8721509..8723488 1 NC_022657.1 COG1533 DNA repair photolyase; hypothetical protein 8723488 17448674 AFR_39995 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739306.1 8721509 D 1246995 CDS YP_008739307.1 556570882 17448675 8724789..8725148 1 NC_022657.1 COG1832 Predicted CoA-binding protein; hypothetical protein 8725148 17448675 AFR_40000 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739307.1 8724789 D 1246995 CDS YP_008739308.1 556570883 17448676 8725293..8725799 1 NC_022657.1 hypothetical protein 8725799 17448676 AFR_40005 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739308.1 8725293 D 1246995 CDS YP_008739309.1 556570884 17448677 complement(8725852..8726796) 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); 3-oxoacyl-ACP reductase 8726796 17448677 AFR_40010 Actinoplanes friuliensis DSM 7358 3-oxoacyl-ACP reductase YP_008739309.1 8725852 R 1246995 CDS YP_008739310.1 556570885 17448678 8726926..8727543 1 NC_022657.1 hypothetical protein 8727543 17448678 AFR_40015 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739310.1 8726926 D 1246995 CDS YP_008739311.1 556570886 17448679 complement(8727540..8728175) 1 NC_022657.1 hypothetical protein 8728175 17448679 AFR_40020 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739311.1 8727540 R 1246995 CDS YP_008739312.1 556570887 17448680 complement(8728220..8729137) 1 NC_022657.1 COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily; hypothetical protein 8729137 17448680 AFR_40025 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739312.1 8728220 R 1246995 CDS YP_008739313.1 556570888 17448681 8729288..8729986 1 NC_022657.1 COG1011 Predicted hydrolase (HAD superfamily); putative HAD-hydrolase 8729986 17448681 AFR_40030 Actinoplanes friuliensis DSM 7358 putative HAD-hydrolase YP_008739313.1 8729288 D 1246995 CDS YP_008739314.1 556570889 17448682 8730007..8730507 1 NC_022657.1 hypothetical protein 8730507 17448682 AFR_40035 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739314.1 8730007 D 1246995 CDS YP_008739315.1 556570890 17448683 complement(8730604..8731467) 1 NC_022657.1 COG0384 Predicted epimerase, PhzC/PhzF homolog; phenazine biosynthesis protein phzf family 8731467 17448683 AFR_40040 Actinoplanes friuliensis DSM 7358 phenazine biosynthesis protein phzf family YP_008739315.1 8730604 R 1246995 CDS YP_008739316.1 556570891 17448684 8731510..8732799 1 NC_022657.1 COG2239 Mg/Co/Ni transporter MgtE (contains CBS domain); Magnesium transporter mgtE 8732799 17448684 AFR_40045 Actinoplanes friuliensis DSM 7358 Magnesium transporter mgtE YP_008739316.1 8731510 D 1246995 CDS YP_008739317.1 556570892 17448685 8732796..8733329 1 NC_022657.1 COG4420 Predicted membrane protein; hypothetical protein 8733329 17448685 AFR_40050 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739317.1 8732796 D 1246995 CDS YP_008739318.1 556570893 17448686 8733351..8734502 1 NC_022657.1 COG0489 ATPases involved in chromosome partitioning; Mrp-like protein 8734502 17448686 AFR_40055 Actinoplanes friuliensis DSM 7358 Mrp-like protein YP_008739318.1 8733351 D 1246995 CDS YP_008739319.1 556570894 17448687 complement(8734506..8734946) 1 NC_022657.1 COG1826 Sec-independent protein secretion pathway components; sec-independent protein translocase protein TatB 8734946 17448687 AFR_40060 Actinoplanes friuliensis DSM 7358 sec-independent protein translocase protein TatB YP_008739319.1 8734506 R 1246995 CDS YP_008739320.1 556570895 17448688 complement(8735024..8736202) 1 NC_022657.1 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain; putative trypsin-like serine protease 8736202 17448688 AFR_40065 Actinoplanes friuliensis DSM 7358 putative trypsin-like serine protease YP_008739320.1 8735024 R 1246995 CDS YP_008739321.1 556570896 17448689 8736459..8737160 1 NC_022657.1 COG4122 Predicted O-methyltransferase; putative O-methyltransferase 8737160 17448689 AFR_40070 Actinoplanes friuliensis DSM 7358 putative O-methyltransferase YP_008739321.1 8736459 D 1246995 CDS YP_008739322.1 556570897 17448690 complement(8737305..8738717) 1 NC_022657.1 COG0260 Leucyl aminopeptidase; leucyl aminopeptidase 8738717 17448690 AFR_40075 Actinoplanes friuliensis DSM 7358 leucyl aminopeptidase YP_008739322.1 8737305 R 1246995 CDS YP_008739323.1 556570898 17448691 complement(8738794..8738961) 1 NC_022657.1 hypothetical protein 8738961 17448691 AFR_40080 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739323.1 8738794 R 1246995 CDS YP_008739324.1 556570899 17448692 8739252..8740064 1 NC_022657.1 COG3327 Phenylacetic acid-responsive transcriptional repressor; putative PaaX-like regulatory protein 8740064 17448692 AFR_40085 Actinoplanes friuliensis DSM 7358 putative PaaX-like regulatory protein YP_008739324.1 8739252 D 1246995 CDS YP_008739325.1 556570900 17448693 8740061..8740894 1 NC_022657.1 COG1024 Enoyl-CoA hydratase/carnithine racemase; enoyl-CoA hydratase/isomerase 8740894 17448693 AFR_40090 Actinoplanes friuliensis DSM 7358 enoyl-CoA hydratase/isomerase YP_008739325.1 8740061 D 1246995 CDS YP_008739326.1 556570901 17448694 8740977..8741774 1 NC_022657.1 COG5640 Secreted trypsin-like serine protease; putative trypsin-like serine protease 8741774 17448694 AFR_40095 Actinoplanes friuliensis DSM 7358 putative trypsin-like serine protease YP_008739326.1 8740977 D 1246995 CDS YP_008739327.1 556570902 17448695 complement(8741823..8742380) 1 NC_022657.1 hypothetical protein 8742380 17448695 AFR_40100 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739327.1 8741823 R 1246995 CDS YP_008739328.1 556570903 17448696 complement(8742447..8743073) 1 NC_022657.1 COG2818 3-methyladenine DNA glycosylase; putative DNA-3-methyladenine glycosylase I 8743073 17448696 AFR_40105 Actinoplanes friuliensis DSM 7358 putative DNA-3-methyladenine glycosylase I YP_008739328.1 8742447 R 1246995 CDS YP_008739329.1 556570904 17448697 complement(8743108..8743605) 1 NC_022657.1 hypothetical protein 8743605 17448697 AFR_40110 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739329.1 8743108 R 1246995 CDS YP_008739330.1 556570905 17448698 complement(8743602..8744144) 1 NC_022657.1 hypothetical protein 8744144 17448698 AFR_40115 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739330.1 8743602 R 1246995 CDS YP_008739331.1 556570906 17448699 complement(8744228..8744605) 1 NC_022657.1 COG0838 NADH:ubiquinone oxidoreductase subunit 3 (chain A); NADH dehydrogenase I subunit A 8744605 17448699 AFR_40120 Actinoplanes friuliensis DSM 7358 NADH dehydrogenase I subunit A YP_008739331.1 8744228 R 1246995 CDS YP_008739332.1 556570907 17448700 8744805..8746658 1 NC_022657.1 COG1014 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit; 2-oxoglutarate ferredoxin oxidoreductase subunit alpha 8746658 17448700 AFR_40125 Actinoplanes friuliensis DSM 7358 2-oxoglutarate ferredoxin oxidoreductase subunit alpha YP_008739332.1 8744805 D 1246995 CDS YP_008739333.1 556570908 17448701 8746651..8747697 1 NC_022657.1 COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit; 2-oxoglutarate ferredoxin oxidoreductase subunit beta 8747697 17448701 AFR_40130 Actinoplanes friuliensis DSM 7358 2-oxoglutarate ferredoxin oxidoreductase subunit beta YP_008739333.1 8746651 D 1246995 CDS YP_008739334.1 556570909 17448702 complement(8747694..8748710) 1 NC_022657.1 COG1226 Kef-type K+ transport systems, predicted NAD-binding component; Potassium channel protein 1 8748710 17448702 AFR_40135 Actinoplanes friuliensis DSM 7358 Potassium channel protein 1 YP_008739334.1 8747694 R 1246995 CDS YP_008739335.1 556570910 17448703 8748896..8749432 1 NC_022657.1 phospholipase a2 8749432 17448703 AFR_40140 Actinoplanes friuliensis DSM 7358 phospholipase a2 YP_008739335.1 8748896 D 1246995 CDS YP_008739336.1 556570911 17448704 complement(8749564..8751906) 1 NC_022657.1 COG3903 Predicted ATPase; hypothetical protein 8751906 17448704 AFR_40145 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739336.1 8749564 R 1246995 CDS YP_008739337.1 556570912 17448705 complement(8753757..8753978) 1 NC_022657.1 regulatory protein, fmdb family 8753978 17448705 AFR_40150 Actinoplanes friuliensis DSM 7358 regulatory protein, fmdb family YP_008739337.1 8753757 R 1246995 CDS YP_008739338.1 556570913 17448706 8755811..8756353 1 NC_022657.1 COG2951 Membrane-bound lytic murein transglycosylase B; hypothetical protein 8756353 17448706 AFR_40155 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739338.1 8755811 D 1246995 CDS YP_008739339.1 556570914 17448707 8756492..8757457 1 NC_022657.1 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; putative GCN5-related N-acetyltransferase 8757457 17448707 AFR_40160 Actinoplanes friuliensis DSM 7358 putative GCN5-related N-acetyltransferase YP_008739339.1 8756492 D 1246995 CDS YP_008739340.1 556570915 17448708 complement(8757451..8758440) 1 NC_022657.1 COG0113 Delta-aminolevulinic acid dehydratase; delta-aminolevulinic acid dehydratase 8758440 17448708 AFR_40165 Actinoplanes friuliensis DSM 7358 delta-aminolevulinic acid dehydratase YP_008739340.1 8757451 R 1246995 CDS YP_008739341.1 556570916 17448709 complement(8758498..8760084) 1 NC_022657.1 COG0007 Uroporphyrinogen-III methylase; putative uroporphyrin-III C-methyltransferase/uroporphyrinogen-III synthase 8760084 17448709 AFR_40170 Actinoplanes friuliensis DSM 7358 putative uroporphyrin-III C-methyltransferase/uroporphyrinogen-III synthase YP_008739341.1 8758498 R 1246995 CDS YP_008739342.1 556570917 17448710 complement(8760081..8761010) 1 NC_022657.1 COG0181 Porphobilinogen deaminase; putative porphobilinogen deaminase 8761010 17448710 AFR_40175 Actinoplanes friuliensis DSM 7358 putative porphobilinogen deaminase YP_008739342.1 8760081 R 1246995 CDS YP_008739343.1 556570918 17448711 complement(8761007..8762302) 1 NC_022657.1 COG0373 Glutamyl-tRNA reductase; glutamyl-tRNA reductase 8762302 hemA 17448711 hemA Actinoplanes friuliensis DSM 7358 glutamyl-tRNA reductase YP_008739343.1 8761007 R 1246995 CDS YP_008739344.1 556570919 17448712 complement(8762299..8763039) 1 NC_022657.1 COG2344 AT-rich DNA-binding protein; putative redox-sensing transcriptional repressor Rex 8763039 17448712 AFR_40185 Actinoplanes friuliensis DSM 7358 putative redox-sensing transcriptional repressor Rex YP_008739344.1 8762299 R 1246995 CDS YP_008739345.1 556570920 17448713 complement(8763300..8763941) 1 NC_022657.1 COG0546 Predicted phosphatases; putative haloacid dehalogenase-like hydrolase 8763941 17448713 AFR_40190 Actinoplanes friuliensis DSM 7358 putative haloacid dehalogenase-like hydrolase YP_008739345.1 8763300 R 1246995 CDS YP_008739346.1 556570921 17448714 complement(8763951..8764199) 1 NC_022657.1 COG0526 Thiol-disulfide isomerase and thioredoxins; putative redoxin 8764199 17448714 AFR_40195 Actinoplanes friuliensis DSM 7358 putative redoxin YP_008739346.1 8763951 R 1246995 CDS YP_008739347.1 556570922 17448715 complement(8764196..8765701) 1 NC_022657.1 COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II; AMP-dependent synthetase and ligase 8765701 17448715 AFR_40200 Actinoplanes friuliensis DSM 7358 AMP-dependent synthetase and ligase YP_008739347.1 8764196 R 1246995 CDS YP_008739348.1 556570923 17448716 8766025..8766966 1 NC_022657.1 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; putative RNA polymerase ECF-subfamily sigma factor 8766966 17448716 AFR_40205 Actinoplanes friuliensis DSM 7358 putative RNA polymerase ECF-subfamily sigma factor YP_008739348.1 8766025 D 1246995 CDS YP_008739349.1 556570924 17448717 8767139..8768305 1 NC_022657.1 hypothetical protein 8768305 17448717 AFR_40210 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739349.1 8767139 D 1246995 CDS YP_008739350.1 556570925 17448718 complement(8768384..8769442) 1 NC_022657.1 COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase; putative acyltransferase 8769442 17448718 AFR_40215 Actinoplanes friuliensis DSM 7358 putative acyltransferase YP_008739350.1 8768384 R 1246995 CDS YP_008739351.1 556570926 17448719 complement(8769439..8770524) 1 NC_022657.1 COG0451 Nucleoside-diphosphate-sugar epimerases; putative NAD-dependent epimerase/dehydratase 8770524 17448719 AFR_40220 Actinoplanes friuliensis DSM 7358 putative NAD-dependent epimerase/dehydratase YP_008739351.1 8769439 R 1246995 CDS YP_008739352.1 556570927 17448720 complement(8770923..8771135) 1 NC_022657.1 COG1910 Periplasmic molybdate-binding protein/domain; hypothetical protein 8771135 17448720 AFR_40225 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739352.1 8770923 R 1246995 CDS YP_008739353.1 556570928 17448721 complement(8771324..8772244) 1 NC_022657.1 COG0506 Proline dehydrogenase; proline dehydrogenase 8772244 17448721 AFR_40230 Actinoplanes friuliensis DSM 7358 proline dehydrogenase YP_008739353.1 8771324 R 1246995 CDS YP_008739354.1 556570929 17448722 8772323..8772859 1 NC_022657.1 hypothetical protein 8772859 17448722 AFR_40235 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739354.1 8772323 D 1246995 CDS YP_008739355.1 556570930 17448723 complement(8772846..8773670) 1 NC_022657.1 COG1082 Sugar phosphate isomerases/epimerases; hypothetical protein 8773670 17448723 AFR_40240 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739355.1 8772846 R 1246995 CDS YP_008739356.1 556570931 17448724 8773810..8774655 1 NC_022657.1 hypothetical protein 8774655 17448724 AFR_40245 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739356.1 8773810 D 1246995 CDS YP_008739357.1 556570932 17448725 8774695..8776131 1 NC_022657.1 hypothetical protein 8776131 17448725 AFR_40250 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739357.1 8774695 D 1246995 CDS YP_008739358.1 556570933 17448726 complement(8776121..8776459) 1 NC_022657.1 hypothetical protein 8776459 17448726 AFR_40255 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739358.1 8776121 R 1246995 CDS YP_008739359.1 556570934 17448727 8776561..8777088 1 NC_022657.1 COG1309 Transcriptional regulator; regulatory protein TetR 8777088 17448727 AFR_40260 Actinoplanes friuliensis DSM 7358 regulatory protein TetR YP_008739359.1 8776561 D 1246995 CDS YP_008739360.1 556570935 17448728 8777147..8778040 1 NC_022657.1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); short-chain dehydrogenase/reductase SDR 8778040 17448728 AFR_40265 Actinoplanes friuliensis DSM 7358 short-chain dehydrogenase/reductase SDR YP_008739360.1 8777147 D 1246995 CDS YP_008739361.1 556570936 17448729 complement(8778049..8778732) 1 NC_022657.1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; putative two-component system response regulator PhoP 8778732 17448729 AFR_40270 Actinoplanes friuliensis DSM 7358 putative two-component system response regulator PhoP YP_008739361.1 8778049 R 1246995 CDS YP_008739362.1 556570937 17448730 complement(8778763..8780106) 1 NC_022657.1 COG0642 Signal transduction histidine kinase; putative two-component system sensor kinase PhoR 8780106 17448730 AFR_40275 Actinoplanes friuliensis DSM 7358 putative two-component system sensor kinase PhoR YP_008739362.1 8778763 R 1246995 CDS YP_008739363.1 556570938 17448731 8780315..8780962 1 NC_022657.1 COG0704 Phosphate uptake regulator; PhoU-like phosphate transport system protein 8780962 17448731 AFR_40280 Actinoplanes friuliensis DSM 7358 PhoU-like phosphate transport system protein YP_008739363.1 8780315 D 1246995 CDS YP_008739364.1 556570939 17448732 complement(8781023..8781772) 1 NC_022657.1 COG0588 Phosphoglycerate mutase 1; phosphoglycerate mutase 8781772 17448732 AFR_40285 Actinoplanes friuliensis DSM 7358 phosphoglycerate mutase YP_008739364.1 8781023 R 1246995 CDS YP_008739365.1 556570940 17448733 8781916..8783319 1 NC_022657.1 COG0477 Permeases of the major facilitator superfamily; major facilitator superfamily protein 8783319 17448733 AFR_40290 Actinoplanes friuliensis DSM 7358 major facilitator superfamily protein YP_008739365.1 8781916 D 1246995 CDS YP_008739366.1 556570941 17448734 complement(8783460..8784935) 1 NC_022657.1 COG0835 Chemotaxis signal transduction protein; CheW protein 8784935 17448734 AFR_40295 Actinoplanes friuliensis DSM 7358 CheW protein YP_008739366.1 8783460 R 1246995 CDS YP_008739367.1 556570942 17448735 complement(8784932..8787775) 1 NC_022657.1 COG2202 FOG: PAS/PAC domain; methyl-accepting chemotaxis transducer/sensory box protein 8787775 17448735 AFR_40300 Actinoplanes friuliensis DSM 7358 methyl-accepting chemotaxis transducer/sensory box protein YP_008739367.1 8784932 R 1246995 CDS YP_008739368.1 556570943 17448736 complement(8788158..8789402) 1 NC_022657.1 COG0477 Permeases of the major facilitator superfamily; yhjO-like MFS-type transporter 8789402 17448736 AFR_40305 Actinoplanes friuliensis DSM 7358 yhjO-like MFS-type transporter YP_008739368.1 8788158 R 1246995 CDS YP_008739369.1 556570944 17448737 complement(8789399..8789893) 1 NC_022657.1 COG0144 tRNA and rRNA cytosine-C5-methylases; hypothetical protein 8789893 17448737 AFR_40310 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739369.1 8789399 R 1246995 CDS YP_008739370.1 556570945 17448738 complement(8789887..8791191) 1 NC_022657.1 COG0438 Glycosyltransferase; putative glycosyltransferase (forming 1D-myo-inosityl 2-acetamido-2-deoxy-alpha-D-glucopyranoside) 8791191 17448738 AFR_40315 Actinoplanes friuliensis DSM 7358 putative glycosyltransferase (forming 1D-myo-inosityl 2-acetamido-2-deoxy-alpha-D-glucopyranoside) YP_008739370.1 8789887 R 1246995 CDS YP_008739371.1 556570946 17448739 8791333..8792091 1 NC_022657.1 COG4221 Short-chain alcohol dehydrogenase of unknown specificity; putative short-chain dehydrogenase 8792091 17448739 AFR_40320 Actinoplanes friuliensis DSM 7358 putative short-chain dehydrogenase YP_008739371.1 8791333 D 1246995 CDS YP_008739372.1 556570947 17448740 8792088..8792891 1 NC_022657.1 hypothetical protein 8792891 17448740 AFR_40325 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739372.1 8792088 D 1246995 CDS YP_008739373.1 556570948 17448741 complement(8792895..8794541) 1 NC_022657.1 COG4124 Beta-mannanase; hypothetical protein 8794541 17448741 AFR_40330 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739373.1 8792895 R 1246995 CDS YP_008739374.1 556570949 17448742 complement(8794810..8795211) 1 NC_022657.1 COG0784 FOG: CheY-like receiver; putative transcriptional regulator ycf27 8795211 17448742 AFR_40335 Actinoplanes friuliensis DSM 7358 putative transcriptional regulator ycf27 YP_008739374.1 8794810 R 1246995 CDS YP_008739375.1 556570950 17448743 complement(8795284..8797008) 1 NC_022657.1 COG1404 Subtilisin-like serine proteases; subtilisin-like serine protease 8797008 17448743 AFR_40340 Actinoplanes friuliensis DSM 7358 subtilisin-like serine protease YP_008739375.1 8795284 R 1246995 CDS YP_008739376.1 556570951 17448744 8797238..8797465 1 NC_022657.1 hypothetical protein 8797465 17448744 AFR_40345 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739376.1 8797238 D 1246995 CDS YP_008739377.1 556570952 17448745 8797545..8799365 1 NC_022657.1 COG0642 Signal transduction histidine kinase; putative two-component system sensor kinase 8799365 17448745 AFR_40350 Actinoplanes friuliensis DSM 7358 putative two-component system sensor kinase YP_008739377.1 8797545 D 1246995 CDS YP_008739378.1 556570953 17448746 complement(8799369..8800181) 1 NC_022657.1 COG5637 Predicted integral membrane protein; hypothetical protein 8800181 17448746 AFR_40355 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739378.1 8799369 R 1246995 CDS YP_008739379.1 556570954 17448747 complement(8800262..8800993) 1 NC_022657.1 COG1387 Histidinol phosphatase and related hydrolases of the PHP family; hypothetical protein 8800993 17448747 AFR_40360 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739379.1 8800262 R 1246995 CDS YP_008739380.1 556570955 17448748 complement(8801116..8802663) 1 NC_022657.1 COG0840 Methyl-accepting chemotaxis protein; putative methyl-accepting chemotaxis protein 8802663 17448748 AFR_40365 Actinoplanes friuliensis DSM 7358 putative methyl-accepting chemotaxis protein YP_008739380.1 8801116 R 1246995 CDS YP_008739381.1 556570956 17448749 8802903..8803724 1 NC_022657.1 COG0739 Membrane proteins related to metalloendopeptidases; putative M23-family peptidase 8803724 17448749 AFR_40370 Actinoplanes friuliensis DSM 7358 putative M23-family peptidase YP_008739381.1 8802903 D 1246995 CDS YP_008739382.1 556570957 17448750 complement(8803785..8804036) 1 NC_022657.1 COG1551 Carbon storage regulator (could also regulate swarming and quorum sensing); putative CsrA-like regulator 8804036 csrA 17448750 csrA Actinoplanes friuliensis DSM 7358 putative CsrA-like regulator YP_008739382.1 8803785 R 1246995 CDS YP_008739383.1 556570958 17448751 complement(8804091..8804489) 1 NC_022657.1 COG1699 Uncharacterized protein conserved in bacteria; putative flagellar assembly protein 8804489 fliW 17448751 fliW Actinoplanes friuliensis DSM 7358 putative flagellar assembly protein YP_008739383.1 8804091 R 1246995 CDS YP_008739384.1 556570959 17448752 complement(8804531..8805445) 1 NC_022657.1 COG1344 Flagellin and related hook-associated proteins; putative flagellar hook-associated protein 8805445 flgL 17448752 flgL Actinoplanes friuliensis DSM 7358 putative flagellar hook-associated protein YP_008739384.1 8804531 R 1246995 CDS YP_008739385.1 556570960 17448753 complement(8805455..8806837) 1 NC_022657.1 COG1256 Flagellar hook-associated protein; putative flagellar hook-associated protein 8806837 flgK 17448753 flgK Actinoplanes friuliensis DSM 7358 putative flagellar hook-associated protein YP_008739385.1 8805455 R 1246995 CDS YP_008739386.1 556570961 17448754 complement(8806837..8807322) 1 NC_022657.1 COG1222 ATP-dependent 26S proteasome regulatory subunit; hypothetical protein 8807322 17448754 AFR_40395 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739386.1 8806837 R 1246995 CDS YP_008739387.1 556570962 17448755 8807553..8808398 1 NC_022657.1 COG1344 Flagellin and related hook-associated proteins; flagellin domain-containing protein 8808398 hag 17448755 hag Actinoplanes friuliensis DSM 7358 flagellin domain-containing protein YP_008739387.1 8807553 D 1246995 CDS YP_008739388.1 556570963 17448756 8808521..8809963 1 NC_022657.1 COG1345 Flagellar capping protein; flagellar hook-associated 2 domain-containing protein 8809963 fliD 17448756 fliD Actinoplanes friuliensis DSM 7358 flagellar hook-associated 2 domain-containing protein YP_008739388.1 8808521 D 1246995 CDS YP_008739389.1 556570964 17448757 8810003..8810374 1 NC_022657.1 COG1516 Flagellin-specific chaperone FliS; Flagellar protein fliS 8810374 fliS 17448757 fliS Actinoplanes friuliensis DSM 7358 Flagellar protein fliS YP_008739389.1 8810003 D 1246995 CDS YP_008739390.1 556570965 17448758 8810380..8810703 1 NC_022657.1 hypothetical protein 8810703 17448758 AFR_40415 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739390.1 8810380 D 1246995 CDS YP_008739391.1 556570966 17448759 8810868..8811215 1 NC_022657.1 COG1815 Flagellar basal body protein; putative flagellar basal-body rod protein 8811215 flgB 17448759 flgB Actinoplanes friuliensis DSM 7358 putative flagellar basal-body rod protein YP_008739391.1 8810868 D 1246995 CDS YP_008739392.1 556570967 17448760 8811221..8811616 1 NC_022657.1 COG1558 Flagellar basal body rod protein; flagellar basal-body rod protein FlgC 8811616 flgC 17448760 flgC Actinoplanes friuliensis DSM 7358 flagellar basal-body rod protein FlgC YP_008739392.1 8811221 D 1246995 CDS YP_008739393.1 556570968 17448761 8811619..8811954 1 NC_022657.1 COG1677 Flagellar hook-basal body protein; flagellar hook-basal body complex protein FliE 8811954 fliE 17448761 fliE Actinoplanes friuliensis DSM 7358 flagellar hook-basal body complex protein FliE YP_008739393.1 8811619 D 1246995 CDS YP_008739394.1 556570969 17448762 8811956..8813557 1 NC_022657.1 COG1766 Flagellar biosynthesis/type III secretory pathway lipoprotein; putative flagellar M-ring protein 8813557 fliF 17448762 fliF Actinoplanes friuliensis DSM 7358 putative flagellar M-ring protein YP_008739394.1 8811956 D 1246995 CDS YP_008739395.1 556570970 17448763 8813600..8814625 1 NC_022657.1 COG1536 Flagellar motor switch protein; putative flagellar motor switch protein 8814625 fliG 17448763 fliG Actinoplanes friuliensis DSM 7358 putative flagellar motor switch protein YP_008739395.1 8813600 D 1246995 CDS YP_008739396.1 556570971 17448764 8814609..8815283 1 NC_022657.1 COG1317 Flagellar biosynthesis/type III secretory pathway protein; putative flagellar assembly protein 8815283 fliH 17448764 fliH Actinoplanes friuliensis DSM 7358 putative flagellar assembly protein YP_008739396.1 8814609 D 1246995 CDS YP_008739397.1 556570972 17448765 8815280..8816587 1 NC_022657.1 COG1157 Flagellar biosynthesis/type III secretory pathway ATPase; putative flagellum-specific ATP synthase 8816587 fliI 17448765 fliI Actinoplanes friuliensis DSM 7358 putative flagellum-specific ATP synthase YP_008739397.1 8815280 D 1246995 CDS YP_008739398.1 556570973 17448766 8816691..8817371 1 NC_022657.1 TolA family protein 8817371 fliJ 17448766 fliJ Actinoplanes friuliensis DSM 7358 TolA family protein YP_008739398.1 8816691 D 1246995 CDS YP_008739399.1 556570974 17448767 8817368..8818315 1 NC_022657.1 COG0791 Cell wall-associated hydrolases (invasion-associated proteins); putative lytic transglycosylase 8818315 17448767 AFR_40460 Actinoplanes friuliensis DSM 7358 putative lytic transglycosylase YP_008739399.1 8817368 D 1246995 CDS YP_008739400.1 556570975 17448768 8818345..8820318 1 NC_022657.1 COG3144 Flagellar hook-length control protein; flagellar hook-length control protein 8820318 17448768 AFR_40465 Actinoplanes friuliensis DSM 7358 flagellar hook-length control protein YP_008739400.1 8818345 D 1246995 CDS YP_008739401.1 556570976 17448769 8820403..8820999 1 NC_022657.1 COG1843 Flagellar hook capping protein; putative flagellar hook capping protein 8820999 flgD 17448769 flgD Actinoplanes friuliensis DSM 7358 putative flagellar hook capping protein YP_008739401.1 8820403 D 1246995 CDS YP_008739402.1 556570977 17448770 8821003..8822214 1 NC_022657.1 COG1749 Flagellar hook protein FlgE; putative flagellar hook rod protein 8822214 flgE 17448770 flgE Actinoplanes friuliensis DSM 7358 putative flagellar hook rod protein YP_008739402.1 8821003 D 1246995 CDS YP_008739403.1 556570978 17448771 8822396..8822683 1 NC_022657.1 COG1582 Uncharacterized protein, possibly involved in motility; flagellar protein FlbD 8822683 flbD 17448771 flbD Actinoplanes friuliensis DSM 7358 flagellar protein FlbD YP_008739403.1 8822396 D 1246995 CDS YP_008739404.1 556570979 17448772 8822683..8823471 1 NC_022657.1 COG1291 Flagellar motor component; putative proton conductor component of motor 8823471 motA 17448772 motA Actinoplanes friuliensis DSM 7358 putative proton conductor component of motor YP_008739404.1 8822683 D 1246995 CDS YP_008739405.1 556570980 17448773 8823474..8824496 1 NC_022657.1 COG1360 Flagellar motor protein; putative flagellar motor protein 8824496 motB 17448773 motB Actinoplanes friuliensis DSM 7358 putative flagellar motor protein YP_008739405.1 8823474 D 1246995 CDS YP_008739406.1 556570981 17448774 8824517..8824984 1 NC_022657.1 COG1580 Flagellar basal body-associated protein; putative flagellar basal body-associated protein 8824984 fliL 17448774 fliL Actinoplanes friuliensis DSM 7358 putative flagellar basal body-associated protein YP_008739406.1 8824517 D 1246995 CDS YP_008739407.1 556570982 17448775 8825100..8826035 1 NC_022657.1 COG1868 Flagellar motor switch protein; Flagellar motor switch protein FliM 8826035 fliM 17448775 fliM Actinoplanes friuliensis DSM 7358 Flagellar motor switch protein FliM YP_008739407.1 8825100 D 1246995 CDS YP_008739408.1 556570983 17448776 8826032..8826778 1 NC_022657.1 COG1886 Flagellar motor switch/type III secretory pathway protein; Flagellar motor switch protein FliN 8826778 fliN 17448776 fliN Actinoplanes friuliensis DSM 7358 Flagellar motor switch protein FliN YP_008739408.1 8826032 D 1246995 CDS YP_008739409.1 556570984 17448777 8826782..8827216 1 NC_022657.1 flagellar protein FliO/FliZ 8827216 fliO 17448777 fliO Actinoplanes friuliensis DSM 7358 flagellar protein FliO/FliZ YP_008739409.1 8826782 D 1246995 CDS YP_008739410.1 556570985 17448778 8827218..8828069 1 NC_022657.1 COG1338 Flagellar biosynthesis pathway, component FliP; flagellar biosynthetic protein FliP 8828069 fliP 17448778 fliP Actinoplanes friuliensis DSM 7358 flagellar biosynthetic protein FliP YP_008739410.1 8827218 D 1246995 CDS YP_008739411.1 556570986 17448779 8828077..8828841 1 NC_022657.1 COG1684 Flagellar biosynthesis pathway, component FliR; flagellar biosynthetic protein FliR 8828841 fliR 17448779 fliR Actinoplanes friuliensis DSM 7358 flagellar biosynthetic protein FliR YP_008739411.1 8828077 D 1246995 CDS YP_008739412.1 556570987 17448780 8828845..8829936 1 NC_022657.1 COG1377 Flagellar biosynthesis pathway, component FlhB; putative flagellar biosynthesis protein 8829936 flhB 17448780 flhB Actinoplanes friuliensis DSM 7358 putative flagellar biosynthesis protein YP_008739412.1 8828845 D 1246995 CDS YP_008739413.1 556570988 17448781 8830006..8832048 1 NC_022657.1 COG1298 Flagellar biosynthesis pathway, component FlhA; Flagellar biosynthesis protein flhA 8832048 flhA 17448781 flhA Actinoplanes friuliensis DSM 7358 Flagellar biosynthesis protein flhA YP_008739413.1 8830006 D 1246995 CDS YP_008739414.1 556570989 17448782 8832038..8833621 1 NC_022657.1 COG1419 Flagellar GTP-binding protein; flagellar GTP-binding protein 8833621 flhF 17448782 flhF Actinoplanes friuliensis DSM 7358 flagellar GTP-binding protein YP_008739414.1 8832038 D 1246995 CDS YP_008739415.1 556570990 17448783 8833624..8833860 1 NC_022657.1 hypothetical protein 8833860 17448783 AFR_40540 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739415.1 8833624 D 1246995 CDS YP_008739416.1 556570991 17448784 8833910..8835004 1 NC_022657.1 COG0628 Predicted permease; hypothetical protein 8835004 17448784 AFR_40545 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739416.1 8833910 D 1246995 CDS YP_008739417.1 556570992 17448785 8835120..8836109 1 NC_022657.1 hypothetical protein 8836109 17448785 AFR_40550 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739417.1 8835120 D 1246995 CDS YP_008739418.1 556570993 17448786 complement(8836250..8836735) 1 NC_022657.1 hypothetical protein 8836735 17448786 AFR_40555 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739418.1 8836250 R 1246995 CDS YP_008739419.1 556570994 17448787 complement(8836743..8837105) 1 NC_022657.1 COG0784 FOG: CheY-like receiver; Ycf27-liketranscriptional regulator 8837105 17448787 AFR_40560 Actinoplanes friuliensis DSM 7358 Ycf27-liketranscriptional regulator YP_008739419.1 8836743 R 1246995 CDS YP_008739420.1 556570995 17448788 complement(8837102..8837581) 1 NC_022657.1 hypothetical protein 8837581 17448788 AFR_40565 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739420.1 8837102 R 1246995 CDS YP_008739421.1 556570996 17448789 complement(8837578..8837964) 1 NC_022657.1 COG0784 FOG: CheY-like receiver; putative response regulator receiver domain protein CheY 8837964 17448789 AFR_40570 Actinoplanes friuliensis DSM 7358 putative response regulator receiver domain protein CheY YP_008739421.1 8837578 R 1246995 CDS YP_008739422.1 556570997 17448790 complement(8837971..8838816) 1 NC_022657.1 COG1352 Methylase of chemotaxis methyl-accepting proteins; chemotaxis protein methyltransferase CheR 8838816 17448790 AFR_40575 Actinoplanes friuliensis DSM 7358 chemotaxis protein methyltransferase CheR YP_008739422.1 8837971 R 1246995 CDS YP_008739423.1 556570998 17448791 complement(8838813..8840006) 1 NC_022657.1 COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain; putative response regulator receiver modulated methylesterase CheB 8840006 17448791 AFR_40580 Actinoplanes friuliensis DSM 7358 putative response regulator receiver modulated methylesterase CheB YP_008739423.1 8838813 R 1246995 CDS YP_008739424.1 556570999 17448792 complement(8840022..8840894) 1 NC_022657.1 COG0056 F0F1-type ATP synthase, alpha subunit; hypothetical protein 8840894 17448792 AFR_40585 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739424.1 8840022 R 1246995 CDS YP_008739425.1 556571000 17448793 complement(8840894..8841331) 1 NC_022657.1 COG0835 Chemotaxis signal transduction protein; Chemotaxis protein cheW 8841331 17448793 AFR_40590 Actinoplanes friuliensis DSM 7358 Chemotaxis protein cheW YP_008739425.1 8840894 R 1246995 CDS YP_008739426.1 556571001 17448794 complement(8841333..8843672) 1 NC_022657.1 COG0643 Chemotaxis protein histidine kinase and related kinases; two-component system, chemotaxis family, sensor kinase CheA 8843672 17448794 AFR_40595 Actinoplanes friuliensis DSM 7358 two-component system, chemotaxis family, sensor kinase CheA YP_008739426.1 8841333 R 1246995 CDS YP_008739427.1 556571002 17448795 complement(8843758..8844456) 1 NC_022657.1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Transcriptional regulatory protein yycF 8844456 17448795 AFR_40600 Actinoplanes friuliensis DSM 7358 Transcriptional regulatory protein yycF YP_008739427.1 8843758 R 1246995 CDS YP_008739428.1 556571003 17448796 8844644..8845351 1 NC_022657.1 COG0642 Signal transduction histidine kinase; integral membrane sensor signal transduction histidine kinase 8845351 17448796 AFR_40605 Actinoplanes friuliensis DSM 7358 integral membrane sensor signal transduction histidine kinase YP_008739428.1 8844644 D 1246995 CDS YP_008739429.1 556571004 17448797 8845466..8845975 1 NC_022657.1 COG2340 Uncharacterized protein with SCP/PR1 domains; hypothetical protein 8845975 17448797 AFR_40610 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739429.1 8845466 D 1246995 CDS YP_008739430.1 556571005 17448798 complement(8845984..8846901) 1 NC_022657.1 COG0812 UDP-N-acetylmuramate dehydrogenase; UDP-N-acetylenolpyruvoylglucosamine reductase 8846901 murB 17448798 murB Actinoplanes friuliensis DSM 7358 UDP-N-acetylenolpyruvoylglucosamine reductase YP_008739430.1 8845984 R 1246995 CDS YP_008739431.1 556571006 17448799 8847139..8847900 1 NC_022657.1 hypothetical protein 8847900 17448799 AFR_40620 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739431.1 8847139 D 1246995 CDS YP_008739432.1 556571007 17448800 8848082..8849509 1 NC_022657.1 COG2723 Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase; putative beta-glucosidase 8849509 17448800 AFR_40625 Actinoplanes friuliensis DSM 7358 putative beta-glucosidase YP_008739432.1 8848082 D 1246995 CDS YP_008739433.1 556571008 17448801 8849514..8850530 1 NC_022657.1 COG1609 Transcriptional regulators; HTH-type transcriptional repressor purR 8850530 17448801 AFR_40630 Actinoplanes friuliensis DSM 7358 HTH-type transcriptional repressor purR YP_008739433.1 8849514 D 1246995 CDS YP_008739434.1 556571009 17448802 complement(8850627..8851163) 1 NC_022657.1 COG2110 Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1; hypothetical protein 8851163 17448802 AFR_40635 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739434.1 8850627 R 1246995 CDS YP_008739435.1 556571010 17448803 complement(8851163..8851975) 1 NC_022657.1 COG2981 Uncharacterized protein involved in cysteine biosynthesis; hypothetical protein 8851975 17448803 AFR_40640 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739435.1 8851163 R 1246995 CDS YP_008739436.1 556571011 17448804 8852027..8852443 1 NC_022657.1 hypothetical protein 8852443 17448804 AFR_40645 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739436.1 8852027 D 1246995 CDS YP_008739437.1 556571012 17448805 8852570..8853601 1 NC_022657.1 COG3291 FOG: PKD repeat; putative 5'-nucleotidase 8853601 17448805 AFR_40650 Actinoplanes friuliensis DSM 7358 putative 5'-nucleotidase YP_008739437.1 8852570 D 1246995 CDS YP_008739438.1 556571013 17448806 complement(8853638..8854528) 1 NC_022657.1 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); hypothetical protein 8854528 17448806 AFR_40655 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739438.1 8853638 R 1246995 CDS YP_008739439.1 556571014 17448807 complement(8854525..8854848) 1 NC_022657.1 hypothetical protein 8854848 17448807 AFR_40660 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739439.1 8854525 R 1246995 CDS YP_008739440.1 556571015 17448808 complement(8854919..8855374) 1 NC_022657.1 hypothetical protein 8855374 17448808 AFR_40665 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739440.1 8854919 R 1246995 CDS YP_008739441.1 556571016 17448809 complement(8855371..8855853) 1 NC_022657.1 COG1396 Predicted transcriptional regulators; XRE family transcriptional regulator 8855853 17448809 AFR_40670 Actinoplanes friuliensis DSM 7358 XRE family transcriptional regulator YP_008739441.1 8855371 R 1246995 CDS YP_008739442.1 556571017 17448810 complement(8855923..8856858) 1 NC_022657.1 COG4448 L-asparaginase II; L-asparaginase II 8856858 17448810 AFR_40675 Actinoplanes friuliensis DSM 7358 L-asparaginase II YP_008739442.1 8855923 R 1246995 CDS YP_008739443.1 556571018 17448811 complement(8856855..8857688) 1 NC_022657.1 COG3246 Uncharacterized conserved protein; hypothetical protein 8857688 17448811 AFR_40680 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739443.1 8856855 R 1246995 CDS YP_008739444.1 556571019 17448812 complement(8857717..8858778) 1 NC_022657.1 COG0354 Predicted aminomethyltransferase related to GcvT; aminomethyltransferase 8858778 17448812 AFR_40685 Actinoplanes friuliensis DSM 7358 aminomethyltransferase YP_008739444.1 8857717 R 1246995 CDS YP_008739445.1 556571020 17448813 complement(8858775..8859200) 1 NC_022657.1 COG0735 Fe2+/Zn2+ uptake regulation proteins; putative Fur-family transcriptional regulator 8859200 17448813 AFR_40690 Actinoplanes friuliensis DSM 7358 putative Fur-family transcriptional regulator YP_008739445.1 8858775 R 1246995 CDS YP_008739446.1 556571021 17448814 8859287..8860027 1 NC_022657.1 COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase; putative aminotransferase 8860027 17448814 AFR_40695 Actinoplanes friuliensis DSM 7358 putative aminotransferase YP_008739446.1 8859287 D 1246995 CDS YP_008739447.1 556571022 17448815 complement(8860117..8860713) 1 NC_022657.1 COG2967 Uncharacterized protein affecting Mg2+/Co2+ transport; fatty acid-binding protein-like protein 8860713 17448815 AFR_40700 Actinoplanes friuliensis DSM 7358 fatty acid-binding protein-like protein YP_008739447.1 8860117 R 1246995 CDS YP_008739448.1 556571023 17448816 8860841..8861203 1 NC_022657.1 COG2044 Predicted peroxiredoxins; dsre family protein 8861203 17448816 AFR_40705 Actinoplanes friuliensis DSM 7358 dsre family protein YP_008739448.1 8860841 D 1246995 CDS YP_008739449.1 556571024 17448817 8861240..8861377 1 NC_022657.1 putative RNA polymerase ECF-subfamily sigma factor 8861377 17448817 AFR_40710 Actinoplanes friuliensis DSM 7358 putative RNA polymerase ECF-subfamily sigma factor YP_008739449.1 8861240 D 1246995 CDS YP_008739450.1 556571025 17448818 8861558..8861935 1 NC_022657.1 hypothetical protein 8861935 17448818 AFR_40715 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739450.1 8861558 D 1246995 CDS YP_008739451.1 556571026 17448819 complement(8861947..8862774) 1 NC_022657.1 hypothetical protein 8862774 17448819 AFR_40720 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739451.1 8861947 R 1246995 CDS YP_008739452.1 556571027 17448820 complement(8863208..8863543) 1 NC_022657.1 hypothetical protein 8863543 17448820 AFR_40725 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739452.1 8863208 R 1246995 CDS YP_008739453.1 556571028 17448821 complement(8863540..8864388) 1 NC_022657.1 COG2897 Rhodanese-related sulfurtransferase; putative thiosulfate sulfurtransferase 8864388 17448821 AFR_40730 Actinoplanes friuliensis DSM 7358 putative thiosulfate sulfurtransferase YP_008739453.1 8863540 R 1246995 CDS YP_008739454.1 556571029 17448822 complement(8864699..8865487) 1 NC_022657.1 hypothetical protein 8865487 17448822 AFR_40735 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739454.1 8864699 R 1246995 CDS YP_008739455.1 556571030 17448823 complement(8865554..8866567) 1 NC_022657.1 hypothetical protein 8866567 17448823 AFR_40740 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739455.1 8865554 R 1246995 CDS YP_008739456.1 556571031 17448824 8866946..8867614 1 NC_022657.1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Transcriptional regulatory protein glnR 8867614 17448824 AFR_40745 Actinoplanes friuliensis DSM 7358 Transcriptional regulatory protein glnR YP_008739456.1 8866946 D 1246995 CDS YP_008739457.1 556571032 17448825 8867626..8868489 1 NC_022657.1 COG0456 Acetyltransferases; putative N-cysteinyl-1-D-myo-inosityl-2-amino-2-deoxy-alpha-D- glucopyranoside acetyltransferase 8868489 17448825 AFR_40750 Actinoplanes friuliensis DSM 7358 putative N-cysteinyl-1-D-myo-inosityl-2-amino-2-deoxy-alpha-D- glucopyranoside acetyltransferase YP_008739457.1 8867626 D 1246995 CDS YP_008739458.1 556571033 17448826 complement(8868648..8869103) 1 NC_022657.1 hypothetical protein 8869103 17448826 AFR_40755 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739458.1 8868648 R 1246995 CDS YP_008739459.1 556571034 17448827 complement(8869103..8870737) 1 NC_022657.1 COG0477 Permeases of the major facilitator superfamily; major facilitator superfamily protein 8870737 17448827 AFR_40760 Actinoplanes friuliensis DSM 7358 major facilitator superfamily protein YP_008739459.1 8869103 R 1246995 CDS YP_008739460.1 556571035 17448828 8871113..8872204 1 NC_022657.1 COG0226 ABC-type phosphate transport system, periplasmic component; putative phosphate ABC transporter substrate-binding protein 8872204 17448828 AFR_40765 Actinoplanes friuliensis DSM 7358 putative phosphate ABC transporter substrate-binding protein YP_008739460.1 8871113 D 1246995 CDS YP_008739461.1 556571036 17448829 8872245..8873330 1 NC_022657.1 COG0573 ABC-type phosphate transport system, permease component; phosphate ABC transporter permease 8873330 17448829 AFR_40770 Actinoplanes friuliensis DSM 7358 phosphate ABC transporter permease YP_008739461.1 8872245 D 1246995 CDS YP_008739462.1 556571037 17448830 8873363..8874409 1 NC_022657.1 COG0581 ABC-type phosphate transport system, permease component; phosphate ABC transporter permease 8874409 17448830 AFR_40775 Actinoplanes friuliensis DSM 7358 phosphate ABC transporter permease YP_008739462.1 8873363 D 1246995 CDS YP_008739463.1 556571038 17448831 8874422..8875198 1 NC_022657.1 COG1117 ABC-type phosphate transport system, ATPase component; phosphate transporter ATP-binding protein 8875198 17448831 AFR_40780 Actinoplanes friuliensis DSM 7358 phosphate transporter ATP-binding protein YP_008739463.1 8874422 D 1246995 CDS YP_008739464.1 556571039 17448832 complement(8875195..8875980) 1 NC_022657.1 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; hypothetical protein 8875980 17448832 AFR_40785 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739464.1 8875195 R 1246995 CDS YP_008739465.1 556571040 17448833 8876019..8877005 1 NC_022657.1 COG0673 Predicted dehydrogenases and related proteins; putative oxidoreductase 8877005 17448833 AFR_40790 Actinoplanes friuliensis DSM 7358 putative oxidoreductase YP_008739465.1 8876019 D 1246995 CDS YP_008739466.1 556571041 17448834 complement(8878275..8879282) 1 NC_022657.1 COG0306 Phosphate/sulphate permeases; putative low-affinity phosphate transporter 8879282 17448834 AFR_40795 Actinoplanes friuliensis DSM 7358 putative low-affinity phosphate transporter YP_008739466.1 8878275 R 1246995 CDS YP_008739467.1 556571042 17448835 complement(8879286..8879912) 1 NC_022657.1 COG1392 Phosphate transport regulator (distant homolog of PhoU); putative Pit accessory protein 8879912 17448835 AFR_40800 Actinoplanes friuliensis DSM 7358 putative Pit accessory protein YP_008739467.1 8879286 R 1246995 CDS YP_008739468.1 556571043 17448836 complement(8880060..8881019) 1 NC_022657.1 hypothetical protein 8881019 17448836 AFR_40805 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739468.1 8880060 R 1246995 CDS YP_008739469.1 556571044 17448837 8881142..8882026 1 NC_022657.1 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; putative RNA polymerase ECF-subfamily sigma factor 8882026 17448837 AFR_40810 Actinoplanes friuliensis DSM 7358 putative RNA polymerase ECF-subfamily sigma factor YP_008739469.1 8881142 D 1246995 CDS YP_008739470.1 556571045 17448838 complement(8882009..8882515) 1 NC_022657.1 COG3557 Uncharacterized domain/protein associated with RNAses G and E; hypothetical protein 8882515 17448838 AFR_40815 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739470.1 8882009 R 1246995 CDS YP_008739471.1 556571046 17448839 8882536..8884590 1 NC_022657.1 COG1199 Rad3-related DNA helicases; putative ATP-dependent helicase 8884590 17448839 AFR_40820 Actinoplanes friuliensis DSM 7358 putative ATP-dependent helicase YP_008739471.1 8882536 D 1246995 CDS YP_008739472.1 556571047 17448840 complement(8885097..8886350) 1 NC_022657.1 COG0628 Predicted permease; hypothetical protein 8886350 17448840 AFR_40825 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739472.1 8885097 R 1246995 CDS YP_008739473.1 556571048 17448841 8886449..8886787 1 NC_022657.1 COG0234 Co-chaperonin GroES (HSP10); putative GroES-family molecular chaperone 8886787 17448841 AFR_40830 Actinoplanes friuliensis DSM 7358 putative GroES-family molecular chaperone YP_008739473.1 8886449 D 1246995 CDS YP_008739474.1 556571049 17448842 complement(8886788..8887534) 1 NC_022657.1 COG0500 SAM-dependent methyltransferases; type 11 methyltransferase 8887534 17448842 AFR_40835 Actinoplanes friuliensis DSM 7358 type 11 methyltransferase YP_008739474.1 8886788 R 1246995 CDS YP_008739475.1 556571050 17448843 complement(8887678..8890179) 1 NC_022657.1 COG2339 Predicted membrane protein; hypothetical protein 8890179 17448843 AFR_40840 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739475.1 8887678 R 1246995 CDS YP_008739476.1 556571051 17448844 complement(8890403..8891608) 1 NC_022657.1 COG4129 Predicted membrane protein; hypothetical protein 8891608 17448844 AFR_40845 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739476.1 8890403 R 1246995 CDS YP_008739477.1 556571052 17448845 8891641..8892279 1 NC_022657.1 COG4339 Uncharacterized protein conserved in bacteria; hypothetical protein 8892279 17448845 AFR_40850 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739477.1 8891641 D 1246995 CDS YP_008739478.1 556571053 17448846 complement(8892263..8892532) 1 NC_022657.1 hypothetical protein 8892532 17448846 AFR_40855 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739478.1 8892263 R 1246995 CDS YP_008739479.1 556571054 17448847 complement(8892529..8894328) 1 NC_022657.1 COG0578 Glycerol-3-phosphate dehydrogenase; glycerol-3-phosphate dehydrogenase 8894328 17448847 AFR_40860 Actinoplanes friuliensis DSM 7358 glycerol-3-phosphate dehydrogenase YP_008739479.1 8892529 R 1246995 CDS YP_008739480.1 556571055 17448848 complement(8894424..8895305) 1 NC_022657.1 COG1733 Predicted transcriptional regulators; putative HXlR-family transcriptional regulator 8895305 17448848 AFR_40865 Actinoplanes friuliensis DSM 7358 putative HXlR-family transcriptional regulator YP_008739480.1 8894424 R 1246995 CDS YP_008739481.1 556571056 17448849 8895361..8896587 1 NC_022657.1 COG0477 Permeases of the major facilitator superfamily; putative MFS transporter 8896587 17448849 AFR_40870 Actinoplanes friuliensis DSM 7358 putative MFS transporter YP_008739481.1 8895361 D 1246995 CDS YP_008739482.1 556571057 17448850 8896599..8897600 1 NC_022657.1 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; GCN5-like N-acetyltransferase 8897600 17448850 AFR_40875 Actinoplanes friuliensis DSM 7358 GCN5-like N-acetyltransferase YP_008739482.1 8896599 D 1246995 CDS YP_008739483.1 556571058 17448851 8897708..8903086 1 NC_022657.1 hypothetical protein 8903086 17448851 AFR_40880 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739483.1 8897708 D 1246995 CDS YP_008739484.1 556571059 17448852 complement(8903243..8904865) 1 NC_022657.1 COG0459 Chaperonin GroEL (HSP60 family); chaperonin GroEL 8904865 groEL 17448852 groEL Actinoplanes friuliensis DSM 7358 chaperonin GroEL YP_008739484.1 8903243 R 1246995 CDS YP_008739485.1 556571060 17448853 8905204..8905728 1 NC_022657.1 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; putative acetyltransferase 8905728 17448853 AFR_40890 Actinoplanes friuliensis DSM 7358 putative acetyltransferase YP_008739485.1 8905204 D 1246995 CDS YP_008739486.1 556571061 17448854 8905725..8906210 1 NC_022657.1 hypothetical protein 8906210 17448854 AFR_40895 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739486.1 8905725 D 1246995 CDS YP_008739487.1 556571062 17448855 complement(8906149..8907096) 1 NC_022657.1 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; N-acetyltransferase GCN5 8907096 17448855 AFR_40900 Actinoplanes friuliensis DSM 7358 N-acetyltransferase GCN5 YP_008739487.1 8906149 R 1246995 CDS YP_008739488.1 556571063 17448856 complement(8907377..8908528) 1 NC_022657.1 COG0498 Threonine synthase; threonine synthase 8908528 17448856 AFR_40905 Actinoplanes friuliensis DSM 7358 threonine synthase YP_008739488.1 8907377 R 1246995 CDS YP_008739489.1 556571064 17448857 8909171..8910163 1 NC_022657.1 COG1131 ABC-type multidrug transport system, ATPase component; putative ABC transporter ATP-binding protein 8910163 17448857 AFR_40910 Actinoplanes friuliensis DSM 7358 putative ABC transporter ATP-binding protein YP_008739489.1 8909171 D 1246995 CDS YP_008739490.1 556571065 17448858 8910160..8911170 1 NC_022657.1 hypothetical protein 8911170 17448858 AFR_40915 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739490.1 8910160 D 1246995 CDS YP_008739491.1 556571066 17448859 8911280..8911591 1 NC_022657.1 hypothetical protein 8911591 17448859 AFR_40920 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739491.1 8911280 D 1246995 CDS YP_008739492.1 556571067 17448860 complement(8911599..8913812) 1 NC_022657.1 COG0464 ATPases of the AAA+ class; putative microtubule-severing ATPase 8913812 17448860 AFR_40925 Actinoplanes friuliensis DSM 7358 putative microtubule-severing ATPase YP_008739492.1 8911599 R 1246995 CDS YP_008739493.1 556571068 17448861 8913891..8914166 1 NC_022657.1 hypothetical protein 8914166 17448861 AFR_40930 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739493.1 8913891 D 1246995 CDS YP_008739494.1 556571069 17448862 8914277..8917000 1 NC_022657.1 COG1131 ABC-type multidrug transport system, ATPase component; putative ABC transporter ATP-binding protein with X-Pro dipeptidyl-peptidase domain 8917000 17448862 AFR_40935 Actinoplanes friuliensis DSM 7358 putative ABC transporter ATP-binding protein with X-Pro dipeptidyl-peptidase domain YP_008739494.1 8914277 D 1246995 CDS YP_008739495.1 556571070 17448863 8916997..8917851 1 NC_022657.1 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component; hypothetical protein 8917851 17448863 AFR_40940 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739495.1 8916997 D 1246995 CDS YP_008739496.1 556571071 17448864 8918163..8918621 1 NC_022657.1 hypothetical protein 8918621 17448864 AFR_40945 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739496.1 8918163 D 1246995 CDS YP_008739497.1 556571072 17448865 8918632..8919105 1 NC_022657.1 hypothetical protein 8919105 17448865 AFR_40950 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739497.1 8918632 D 1246995 CDS YP_008739498.1 556571073 17448866 8919128..8919547 1 NC_022657.1 hypothetical protein 8919547 17448866 AFR_40955 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739498.1 8919128 D 1246995 CDS YP_008739499.1 556571074 17448867 8919540..8919860 1 NC_022657.1 hypothetical protein 8919860 17448867 AFR_40960 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739499.1 8919540 D 1246995 CDS YP_008739500.1 556571075 17448868 8919867..8920568 1 NC_022657.1 hypothetical protein 8920568 17448868 AFR_40965 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739500.1 8919867 D 1246995 CDS YP_008739501.1 556571076 17448869 complement(8920630..8921208) 1 NC_022657.1 COG3544 Uncharacterized protein conserved in bacteria; hypothetical protein 8921208 17448869 AFR_40970 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739501.1 8920630 R 1246995 CDS YP_008739502.1 556571077 17448870 complement(8921205..8922026) 1 NC_022657.1 COG3397 Uncharacterized protein conserved in bacteria; putative secreted chitin-binding protein 8922026 17448870 AFR_40975 Actinoplanes friuliensis DSM 7358 putative secreted chitin-binding protein YP_008739502.1 8921205 R 1246995 CDS YP_008739503.1 556571078 17448871 complement(8922119..8923447) 1 NC_022657.1 COG0642 Signal transduction histidine kinase; putative two-component system sensor kinase 8923447 17448871 AFR_40980 Actinoplanes friuliensis DSM 7358 putative two-component system sensor kinase YP_008739503.1 8922119 R 1246995 CDS YP_008739504.1 556571079 17448872 complement(8923444..8924130) 1 NC_022657.1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; putative transcriptional regulator ycf27 8924130 17448872 AFR_40985 Actinoplanes friuliensis DSM 7358 putative transcriptional regulator ycf27 YP_008739504.1 8923444 R 1246995 CDS YP_008739505.1 556571080 17448873 8924193..8924786 1 NC_022657.1 hypothetical protein 8924786 17448873 AFR_40990 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739505.1 8924193 D 1246995 CDS YP_008739506.1 556571081 17448874 8924879..8925796 1 NC_022657.1 COG0463 Glycosyltransferases involved in cell wall biogenesis; Amylovoran biosynthesis glycosyltransferase amsB 8925796 17448874 AFR_40995 Actinoplanes friuliensis DSM 7358 Amylovoran biosynthesis glycosyltransferase amsB YP_008739506.1 8924879 D 1246995 CDS YP_008739507.1 556571082 17448875 8925786..8926925 1 NC_022657.1 COG0438 Glycosyltransferase; putative glycosyltransferase 8926925 17448875 AFR_41000 Actinoplanes friuliensis DSM 7358 putative glycosyltransferase YP_008739507.1 8925786 D 1246995 CDS YP_008739508.1 556571083 17448876 complement(8926873..8928192) 1 NC_022657.1 hypothetical protein 8928192 17448876 AFR_41005 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739508.1 8926873 R 1246995 CDS YP_008739509.1 556571084 17448877 complement(8928189..8929007) 1 NC_022657.1 hypothetical protein 8929007 17448877 AFR_41010 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739509.1 8928189 R 1246995 CDS YP_008739510.1 556571085 17448878 complement(8929066..8929851) 1 NC_022657.1 COG1349 Transcriptional regulators of sugar metabolism; DeoR family transcriptional regulator 8929851 17448878 AFR_41015 Actinoplanes friuliensis DSM 7358 DeoR family transcriptional regulator YP_008739510.1 8929066 R 1246995 CDS YP_008739511.1 556571086 17448879 8930039..8930962 1 NC_022657.1 COG2222 Predicted phosphosugar isomerases; putative phosphosugar isomerase 8930962 17448879 AFR_41020 Actinoplanes friuliensis DSM 7358 putative phosphosugar isomerase YP_008739511.1 8930039 D 1246995 CDS YP_008739512.1 556571087 17448880 8931032..8931958 1 NC_022657.1 COG1940 Transcriptional regulator/sugar kinase; glucokinase 8931958 17448880 AFR_41025 Actinoplanes friuliensis DSM 7358 glucokinase YP_008739512.1 8931032 D 1246995 CDS YP_008739513.1 556571088 17448881 8931955..8933082 1 NC_022657.1 COG1820 N-acetylglucosamine-6-phosphate deacetylase; putative N-acetylglucosamine-6-phosphate deacetylase 8933082 17448881 AFR_41030 Actinoplanes friuliensis DSM 7358 putative N-acetylglucosamine-6-phosphate deacetylase YP_008739513.1 8931955 D 1246995 CDS YP_008739514.1 556571089 17448882 complement(8933051..8933452) 1 NC_022657.1 hypothetical protein 8933452 17448882 AFR_41035 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739514.1 8933051 R 1246995 CDS YP_008739515.1 556571090 17448883 complement(8933462..8934199) 1 NC_022657.1 COG0671 Membrane-associated phospholipid phosphatase; putative phosphatase 8934199 17448883 AFR_41040 Actinoplanes friuliensis DSM 7358 putative phosphatase YP_008739515.1 8933462 R 1246995 CDS YP_008739516.1 556571091 17448884 complement(8934215..8935606) 1 NC_022657.1 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain; Glutamyl endopeptidase 8935606 17448884 AFR_41045 Actinoplanes friuliensis DSM 7358 Glutamyl endopeptidase YP_008739516.1 8934215 R 1246995 CDS YP_008739517.1 556571092 17448885 8935695..8936942 1 NC_022657.1 hypothetical protein 8936942 17448885 AFR_41050 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739517.1 8935695 D 1246995 CDS YP_008739518.1 556571093 17448886 complement(8936939..8938723) 1 NC_022657.1 COG1226 Kef-type K+ transport systems, predicted NAD-binding component; hypothetical protein 8938723 17448886 AFR_41055 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739518.1 8936939 R 1246995 CDS YP_008739519.1 556571094 17448887 8938842..8939780 1 NC_022657.1 hypothetical protein 8939780 17448887 AFR_41060 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739519.1 8938842 D 1246995 CDS YP_008739520.1 556571095 17448888 complement(8939840..8943049) 1 NC_022657.1 COG1404 Subtilisin-like serine proteases; putative subtilase-family protease 8943049 17448888 AFR_41065 Actinoplanes friuliensis DSM 7358 putative subtilase-family protease YP_008739520.1 8939840 R 1246995 CDS YP_008739521.1 556571096 17448889 8943337..8943816 1 NC_022657.1 hypothetical protein 8943816 17448889 AFR_41070 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739521.1 8943337 D 1246995 CDS YP_008739522.1 556571097 17448890 complement(8943805..8944992) 1 NC_022657.1 COG4292 Predicted membrane protein; hypothetical protein 8944992 17448890 AFR_41075 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739522.1 8943805 R 1246995 CDS YP_008739523.1 556571098 17448891 complement(8944989..8945417) 1 NC_022657.1 COG0456 Acetyltransferases; hypothetical protein 8945417 17448891 AFR_41080 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739523.1 8944989 R 1246995 CDS YP_008739524.1 556571099 17448893 8945719..8946804 1 NC_022657.1 COG3839 ABC-type sugar transport systems, ATPase components; spermidine/putrescine import ATP-binding protein potA 8946804 17448893 AFR_41085 Actinoplanes friuliensis DSM 7358 spermidine/putrescine import ATP-binding protein potA YP_008739524.1 8945719 D 1246995 CDS YP_008739525.1 556571100 17448894 complement(8946862..8949744) 1 NC_022657.1 COG0443 Molecular chaperone; heat shock protein 70 8949744 17448894 AFR_41090 Actinoplanes friuliensis DSM 7358 heat shock protein 70 YP_008739525.1 8946862 R 1246995 CDS YP_008739526.1 556571101 17448895 complement(8949802..8950920) 1 NC_022657.1 COG0566 rRNA methylases; TrmH family RNA methyltransferase 8950920 17448895 AFR_41095 Actinoplanes friuliensis DSM 7358 TrmH family RNA methyltransferase YP_008739526.1 8949802 R 1246995 CDS YP_008739527.1 556571102 17448896 complement(8950920..8952335) 1 NC_022657.1 COG0215 Cysteinyl-tRNA synthetase; cysteinyl-tRNA ligase 8952335 cysS 17448896 cysS Actinoplanes friuliensis DSM 7358 cysteinyl-tRNA ligase YP_008739527.1 8950920 R 1246995 CDS YP_008739528.1 556571103 17448897 8952450..8953361 1 NC_022657.1 COG2852 Uncharacterized protein conserved in bacteria; hypothetical protein 8953361 17448897 AFR_41105 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739528.1 8952450 D 1246995 CDS YP_008739529.1 556571104 17448898 complement(8954110..8955750) 1 NC_022657.1 COG1404 Subtilisin-like serine proteases; putative secreted subtilisin-like serine protease 8955750 17448898 AFR_41110 Actinoplanes friuliensis DSM 7358 putative secreted subtilisin-like serine protease YP_008739529.1 8954110 R 1246995 CDS YP_008739530.1 556571105 17448899 complement(8955793..8957193) 1 NC_022657.1 COG0114 Fumarase; fumarate hydratase 8957193 fumC2 17448899 fumC2 Actinoplanes friuliensis DSM 7358 fumarate hydratase YP_008739530.1 8955793 R 1246995 CDS YP_008739531.1 556571106 17448900 8957340..8957855 1 NC_022657.1 COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; hypothetical protein 8957855 17448900 AFR_41120 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739531.1 8957340 D 1246995 CDS YP_008739532.1 556571107 17448901 8957946..8960057 1 NC_022657.1 hypothetical protein 8960057 17448901 AFR_41125 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739532.1 8957946 D 1246995 CDS YP_008739533.1 556571108 17448902 8960175..8962253 1 NC_022657.1 hypothetical protein 8962253 17448902 AFR_41130 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739533.1 8960175 D 1246995 CDS YP_008739534.1 556571109 17448903 complement(8962391..8964058) 1 NC_022657.1 COG1951 Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain; fumarate hydratase 8964058 17448903 AFR_41135 Actinoplanes friuliensis DSM 7358 fumarate hydratase YP_008739534.1 8962391 R 1246995 CDS YP_008739535.1 556571110 17448904 complement(8964129..8965445) 1 NC_022657.1 hypothetical protein 8965445 17448904 AFR_41140 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739535.1 8964129 R 1246995 CDS YP_008739536.1 556571111 17448905 complement(8965508..8965993) 1 NC_022657.1 COG1522 Transcriptional regulators; putative HTH-type transcriptional regulator 8965993 17448905 AFR_41145 Actinoplanes friuliensis DSM 7358 putative HTH-type transcriptional regulator YP_008739536.1 8965508 R 1246995 CDS YP_008739537.1 556571112 17448906 8966082..8967236 1 NC_022657.1 COG3185 4-hydroxyphenylpyruvate dioxygenase and related hemolysins; 4-hydroxyphenylpyruvate dioxygenase 8967236 17448906 AFR_41150 Actinoplanes friuliensis DSM 7358 4-hydroxyphenylpyruvate dioxygenase YP_008739537.1 8966082 D 1246995 CDS YP_008739538.1 556571113 17448907 8967442..8968098 1 NC_022657.1 COG1714 Predicted membrane protein/domain; RDD domain-containing protein 8968098 17448907 AFR_41155 Actinoplanes friuliensis DSM 7358 RDD domain-containing protein YP_008739538.1 8967442 D 1246995 CDS YP_008739539.1 556571114 17448908 8968824..8969345 1 NC_022657.1 COG1714 Predicted membrane protein/domain; Protein piccolo 8969345 17448908 AFR_41160 Actinoplanes friuliensis DSM 7358 Protein piccolo YP_008739539.1 8968824 D 1246995 CDS YP_008739540.1 556571115 17448909 8969342..8970424 1 NC_022657.1 COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; histidinol-phosphate aminotransferase 8970424 17448909 AFR_41165 Actinoplanes friuliensis DSM 7358 histidinol-phosphate aminotransferase YP_008739540.1 8969342 D 1246995 CDS YP_008739541.1 556571116 17448910 complement(8970582..8972813) 1 NC_022657.1 COG0577 ABC-type antimicrobial peptide transport system, permease component; hypothetical protein 8972813 17448910 AFR_41170 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739541.1 8970582 R 1246995 CDS YP_008739542.1 556571117 17448911 complement(8972807..8973532) 1 NC_022657.1 COG1136 ABC-type antimicrobial peptide transport system, ATPase component; ABC transporter ATP-binding protein 8973532 17448911 AFR_41175 Actinoplanes friuliensis DSM 7358 ABC transporter ATP-binding protein YP_008739542.1 8972807 R 1246995 CDS YP_008739543.1 556571118 17448912 8973625..8974818 1 NC_022657.1 COG4585 Signal transduction histidine kinase; histidine kinase 8974818 17448912 AFR_41180 Actinoplanes friuliensis DSM 7358 histidine kinase YP_008739543.1 8973625 D 1246995 CDS YP_008739544.1 556571119 17448913 8974845..8975567 1 NC_022657.1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; response regulator receiver protein 8975567 17448913 AFR_41185 Actinoplanes friuliensis DSM 7358 response regulator receiver protein YP_008739544.1 8974845 D 1246995 CDS YP_008739545.1 556571120 17448914 complement(8975488..8976684) 1 NC_022657.1 COG2814 Arabinose efflux permease; putative sugar efflux transporter 8976684 17448914 AFR_41190 Actinoplanes friuliensis DSM 7358 putative sugar efflux transporter YP_008739545.1 8975488 R 1246995 CDS YP_008739546.1 556571121 17448915 8976728..8977840 1 NC_022657.1 COG1940 Transcriptional regulator/sugar kinase; putative ROK-family protein 8977840 17448915 AFR_41195 Actinoplanes friuliensis DSM 7358 putative ROK-family protein YP_008739546.1 8976728 D 1246995 CDS YP_008739547.1 556571122 17448916 complement(8978186..8979289) 1 NC_022657.1 COG1520 FOG: WD40-like repeat; hypothetical protein 8979289 17448916 AFR_41200 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739547.1 8978186 R 1246995 CDS YP_008739548.1 556571123 17448917 complement(8979304..8979762) 1 NC_022657.1 COG3832 Uncharacterized conserved protein; polyketide cyclase/dehydrase 8979762 17448917 AFR_41205 Actinoplanes friuliensis DSM 7358 polyketide cyclase/dehydrase YP_008739548.1 8979304 R 1246995 CDS YP_008739549.1 556571124 17448918 complement(8979802..8980926) 1 NC_022657.1 COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway); fumarylacetoacetase 8980926 17448918 AFR_41210 Actinoplanes friuliensis DSM 7358 fumarylacetoacetase YP_008739549.1 8979802 R 1246995 CDS YP_008739550.1 556571125 17448919 complement(8980923..8981768) 1 NC_022657.1 hypothetical protein 8981768 17448919 AFR_41215 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739550.1 8980923 R 1246995 CDS YP_008739551.1 556571126 17448920 8981847..8983001 1 NC_022657.1 COG3508 Homogentisate 1,2-dioxygenase; homogentisate 1,2-dioxygenase 8983001 17448920 AFR_41220 Actinoplanes friuliensis DSM 7358 homogentisate 1,2-dioxygenase YP_008739551.1 8981847 D 1246995 CDS YP_008739552.1 556571127 17448921 complement(8983057..8984292) 1 NC_022657.1 putative glycosyl hydrolase 8984292 17448921 AFR_41225 Actinoplanes friuliensis DSM 7358 putative glycosyl hydrolase YP_008739552.1 8983057 R 1246995 CDS YP_008739553.1 556571128 17448922 8984627..8985775 1 NC_022657.1 COG1940 Transcriptional regulator/sugar kinase; Putative xylose repressor 8985775 17448922 AFR_41230 Actinoplanes friuliensis DSM 7358 Putative xylose repressor YP_008739553.1 8984627 D 1246995 CDS YP_008739554.1 556571129 17448923 8985845..8987137 1 NC_022657.1 COG2182 Maltose-binding periplasmic proteins/domains; Maltotriose-binding protein 8987137 17448923 AFR_41235 Actinoplanes friuliensis DSM 7358 Maltotriose-binding protein YP_008739554.1 8985845 D 1246995 CDS YP_008739555.1 556571130 17448924 8987140..8988057 1 NC_022657.1 COG1175 ABC-type sugar transport systems, permease components; sn-glycerol-3-phosphate transport system permease protein ugpA 8988057 17448924 AFR_41240 Actinoplanes friuliensis DSM 7358 sn-glycerol-3-phosphate transport system permease protein ugpA YP_008739555.1 8987140 D 1246995 CDS YP_008739556.1 556571131 17448925 8988054..8988935 1 NC_022657.1 COG0395 ABC-type sugar transport system, permease component; sugar ABC transporter permease 8988935 17448925 AFR_41245 Actinoplanes friuliensis DSM 7358 sugar ABC transporter permease YP_008739556.1 8988054 D 1246995 CDS YP_008739557.1 556571132 17448926 8988932..8990188 1 NC_022657.1 COG1486 Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases; 6-phospho-beta-glucosidase 8990188 17448926 AFR_41250 Actinoplanes friuliensis DSM 7358 6-phospho-beta-glucosidase YP_008739557.1 8988932 D 1246995 CDS YP_008739558.1 556571133 17448927 8990176..8991204 1 NC_022657.1 COG2971 Predicted N-acetylglucosamine kinase; BadF/BadG/BcrA/BcrD type ATPase 8991204 17448927 AFR_41255 Actinoplanes friuliensis DSM 7358 BadF/BadG/BcrA/BcrD type ATPase YP_008739558.1 8990176 D 1246995 CDS YP_008739559.1 556571134 17448928 complement(8991188..8992264) 1 NC_022657.1 hypothetical protein 8992264 17448928 AFR_41260 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739559.1 8991188 R 1246995 CDS YP_008739560.1 556571135 17448929 complement(8992283..8992672) 1 NC_022657.1 COG0259 Pyridoxamine-phosphate oxidase; putative pyridoxamine 5'-phosphate oxidase-related protein 8992672 17448929 AFR_41265 Actinoplanes friuliensis DSM 7358 putative pyridoxamine 5'-phosphate oxidase-related protein YP_008739560.1 8992283 R 1246995 CDS YP_008739561.1 556571136 17448930 complement(8992669..8993160) 1 NC_022657.1 COG0245 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; 2-C-methyl-D-erythritol 2, 4-cyclodiphosphate synthase 8993160 17448930 AFR_41270 Actinoplanes friuliensis DSM 7358 2-C-methyl-D-erythritol 2, 4-cyclodiphosphate synthase YP_008739561.1 8992669 R 1246995 CDS YP_008739562.1 556571137 17448931 complement(8993165..8993857) 1 NC_022657.1 COG1211 4-diphosphocytidyl-2-methyl-D-erithritol synthase; 2-c-methyl-d-erythritol 4-phosphate cytidylyltransferase 8993857 17448931 AFR_41275 Actinoplanes friuliensis DSM 7358 2-c-methyl-d-erythritol 4-phosphate cytidylyltransferase YP_008739562.1 8993165 R 1246995 CDS YP_008739563.1 556571138 17448932 complement(8993915..8994400) 1 NC_022657.1 COG1329 Transcriptional regulators, similar to M. xanthus CarD; CarD family transcriptional regulator 8994400 17448932 AFR_41280 Actinoplanes friuliensis DSM 7358 CarD family transcriptional regulator YP_008739563.1 8993915 R 1246995 CDS YP_008739564.1 556571139 17448933 8994733..8995506 1 NC_022657.1 hypothetical protein 8995506 17448933 AFR_41285 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739564.1 8994733 D 1246995 CDS YP_008739565.1 556571140 17448934 complement(8995535..8995996) 1 NC_022657.1 hypothetical protein 8995996 17448934 AFR_41290 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739565.1 8995535 R 1246995 CDS YP_008739566.1 556571141 17448935 complement(8996006..8997067) 1 NC_022657.1 COG3424 Predicted naringenin-chalcone synthase; putative type-III polyketide synthase 8997067 17448935 AFR_41295 Actinoplanes friuliensis DSM 7358 putative type-III polyketide synthase YP_008739566.1 8996006 R 1246995 CDS YP_008739567.1 556571142 17448936 complement(8997120..8998277) 1 NC_022657.1 COG1960 Acyl-CoA dehydrogenases; acyl-CoA dehydrogenase type 2 8998277 17448936 AFR_41300 Actinoplanes friuliensis DSM 7358 acyl-CoA dehydrogenase type 2 YP_008739567.1 8997120 R 1246995 CDS YP_008739568.1 556571143 17448937 complement(8998274..8998993) 1 NC_022657.1 COG2227 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase; 3-demethylubiquinone-9 3-methyltransferase 8998993 17448937 AFR_41305 Actinoplanes friuliensis DSM 7358 3-demethylubiquinone-9 3-methyltransferase YP_008739568.1 8998274 R 1246995 CDS YP_008739569.1 556571144 17448938 8999046..8999882 1 NC_022657.1 COG0382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases; 6-alkyl-2-methoxyhydroquinones prenyltransferase 8999882 17448938 AFR_41310 Actinoplanes friuliensis DSM 7358 6-alkyl-2-methoxyhydroquinones prenyltransferase YP_008739569.1 8999046 D 1246995 CDS YP_008739570.1 556571145 17448939 8999971..9000717 1 NC_022657.1 Regulator of G-protein signaling 12 9000717 17448939 AFR_41315 Actinoplanes friuliensis DSM 7358 Regulator of G-protein signaling 12 YP_008739570.1 8999971 D 1246995 CDS YP_008739571.1 556571146 17448940 9000897..9002177 1 NC_022657.1 COG1066 Predicted ATP-dependent serine protease; DNA repair protein RadA 9002177 17448940 AFR_41320 Actinoplanes friuliensis DSM 7358 DNA repair protein RadA YP_008739571.1 9000897 D 1246995 CDS YP_008739572.1 556571147 17448941 9002278..9003462 1 NC_022657.1 COG1623 Predicted nucleic-acid-binding protein (contains the HHH domain); DNA integrity scanning protein DisA 9003462 17448941 AFR_41325 Actinoplanes friuliensis DSM 7358 DNA integrity scanning protein DisA YP_008739572.1 9002278 D 1246995 CDS YP_008739573.1 556571148 17448942 complement(9003624..9004361) 1 NC_022657.1 hypothetical protein 9004361 17448942 AFR_41330 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739573.1 9003624 R 1246995 CDS YP_008739574.1 556571149 17448943 complement(9004476..9005027) 1 NC_022657.1 COG0242 N-formylmethionyl-tRNA deformylase; putative polypeptide deformylase 9005027 17448943 AFR_41335 Actinoplanes friuliensis DSM 7358 putative polypeptide deformylase YP_008739574.1 9004476 R 1246995 CDS YP_008739575.1 556571150 17448944 complement(9005024..9005527) 1 NC_022657.1 COG3830 ACT domain-containing protein; putative amino acid-binding protein 9005527 17448944 AFR_41340 Actinoplanes friuliensis DSM 7358 putative amino acid-binding protein YP_008739575.1 9005024 R 1246995 CDS YP_008739576.1 556571151 17448945 9005553..9006455 1 NC_022657.1 COG1194 A/G-specific DNA glycosylase; putative adenine glycosylase 9006455 17448945 AFR_41345 Actinoplanes friuliensis DSM 7358 putative adenine glycosylase YP_008739576.1 9005553 D 1246995 CDS YP_008739577.1 556571152 17448946 complement(9006448..9007023) 1 NC_022657.1 hypothetical protein 9007023 17448946 AFR_41350 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739577.1 9006448 R 1246995 CDS YP_008739578.1 556571153 17448947 complement(9007111..9009633) 1 NC_022657.1 COG0542 ATPases with chaperone activity, ATP-binding subunit; Chaperone protein clpB 9009633 17448947 AFR_41355 Actinoplanes friuliensis DSM 7358 Chaperone protein clpB YP_008739578.1 9007111 R 1246995 CDS YP_008739579.1 556571154 17448948 complement(9009990..9010343) 1 NC_022657.1 hypothetical protein 9010343 17448948 AFR_41360 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739579.1 9009990 R 1246995 CDS YP_008739580.1 556571155 17448949 complement(9010477..9011988) 1 NC_022657.1 COG1190 Lysyl-tRNA synthetase (class II); putative lysyl-tRNA synthetase 9011988 17448949 AFR_41365 Actinoplanes friuliensis DSM 7358 putative lysyl-tRNA synthetase YP_008739580.1 9010477 R 1246995 CDS YP_008739581.1 556571156 17448950 complement(9012047..9012808) 1 NC_022657.1 COG1521 Putative transcriptional regulator, homolog of Bvg accessory factor; type III pantothenate kinase 9012808 17448950 AFR_41370 Actinoplanes friuliensis DSM 7358 type III pantothenate kinase YP_008739581.1 9012047 R 1246995 CDS YP_008739582.1 556571157 17448951 complement(9012931..9013791) 1 NC_022657.1 COG0157 Nicotinate-nucleotide pyrophosphorylase; putative quinolinate phosphoribosyltransferase 9013791 17448951 AFR_41375 Actinoplanes friuliensis DSM 7358 putative quinolinate phosphoribosyltransferase YP_008739582.1 9012931 R 1246995 CDS YP_008739583.1 556571158 17448952 complement(9013788..9015434) 1 NC_022657.1 COG0029 Aspartate oxidase; L-aspartate oxidase 9015434 17448952 AFR_41380 Actinoplanes friuliensis DSM 7358 L-aspartate oxidase YP_008739583.1 9013788 R 1246995 CDS YP_008739584.1 556571159 17448953 complement(9015497..9016411) 1 NC_022657.1 hypothetical protein 9016411 17448953 AFR_41385 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739584.1 9015497 R 1246995 CDS YP_008739585.1 556571160 17448954 complement(9016518..9017351) 1 NC_022657.1 COG0414 Panthothenate synthetase; putative pantoate-amino acid ligase 9017351 17448954 AFR_41390 Actinoplanes friuliensis DSM 7358 putative pantoate-amino acid ligase YP_008739585.1 9016518 R 1246995 CDS YP_008739586.1 556571161 17448955 complement(9017348..9018235) 1 NC_022657.1 COG5495 Uncharacterized conserved protein; hypothetical protein 9018235 17448955 AFR_41395 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739586.1 9017348 R 1246995 CDS YP_008739587.1 556571162 17448956 9018316..9019335 1 NC_022657.1 COG1565 Uncharacterized conserved protein; hypothetical protein 9019335 17448956 AFR_41400 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739587.1 9018316 D 1246995 CDS YP_008739588.1 556571163 17448957 9019356..9020480 1 NC_022657.1 COG0649 NADH:ubiquinone oxidoreductase 49 kD subunit 7; NADH dehydrogenase I subunit D 9020480 17448957 AFR_41405 Actinoplanes friuliensis DSM 7358 NADH dehydrogenase I subunit D YP_008739588.1 9019356 D 1246995 CDS YP_008739589.1 556571164 17448958 complement(9020489..9021385) 1 NC_022657.1 hypothetical protein 9021385 17448958 AFR_41410 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739589.1 9020489 R 1246995 CDS YP_008739590.1 556571165 17448959 9022799..9023230 1 NC_022657.1 hypothetical protein 9023230 17448959 AFR_41415 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739590.1 9022799 D 1246995 CDS YP_008739591.1 556571166 17448960 complement(9023199..9024200) 1 NC_022657.1 COG1732 Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein); Glycine betaine/carnitine/choline-binding protein 9024200 17448960 AFR_41420 Actinoplanes friuliensis DSM 7358 Glycine betaine/carnitine/choline-binding protein YP_008739591.1 9023199 R 1246995 CDS YP_008739592.1 556571167 17448961 complement(9024364..9025080) 1 NC_022657.1 COG1174 ABC-type proline/glycine betaine transport systems, permease component; binding-protein-dependent transport systems inner membrane component 9025080 17448961 AFR_41425 Actinoplanes friuliensis DSM 7358 binding-protein-dependent transport systems inner membrane component YP_008739592.1 9024364 R 1246995 CDS YP_008739593.1 556571168 17448962 complement(9025077..9025799) 1 NC_022657.1 COG1174 ABC-type proline/glycine betaine transport systems, permease component; binding-protein-dependent transport system inner membrane protein 9025799 17448962 AFR_41430 Actinoplanes friuliensis DSM 7358 binding-protein-dependent transport system inner membrane protein YP_008739593.1 9025077 R 1246995 CDS YP_008739594.1 556571169 17448963 9025802..9026818 1 NC_022657.1 COG1125 ABC-type proline/glycine betaine transport systems, ATPase components; spermidine/putrescine import ATP-binding protein potA 9026818 17448963 AFR_41435 Actinoplanes friuliensis DSM 7358 spermidine/putrescine import ATP-binding protein potA YP_008739594.1 9025802 D 1246995 CDS YP_008739595.1 556571170 17448964 complement(9026960..9027451) 1 NC_022657.1 hypothetical protein 9027451 17448964 AFR_41440 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739595.1 9026960 R 1246995 CDS YP_008739596.1 556571171 17448965 complement(9027530..9027814) 1 NC_022657.1 hypothetical protein 9027814 17448965 AFR_41445 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739596.1 9027530 R 1246995 CDS YP_008739597.1 556571172 17448966 complement(9027845..9029131) 1 NC_022657.1 hypothetical protein 9029131 17448966 AFR_41450 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739597.1 9027845 R 1246995 CDS YP_008739598.1 556571173 17448967 complement(9029177..9029695) 1 NC_022657.1 hypothetical protein 9029695 17448967 AFR_41455 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739598.1 9029177 R 1246995 CDS YP_008739599.1 556571174 17448968 complement(9029692..9030219) 1 NC_022657.1 COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase; putative 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase 9030219 17448968 AFR_41460 Actinoplanes friuliensis DSM 7358 putative 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase YP_008739599.1 9029692 R 1246995 CDS YP_008739600.1 556571175 17448969 complement(9030216..9030575) 1 NC_022657.1 COG1539 Dihydroneopterin aldolase; putative dihydroneopterin aldolase 9030575 17448969 AFR_41465 Actinoplanes friuliensis DSM 7358 putative dihydroneopterin aldolase YP_008739600.1 9030216 R 1246995 CDS YP_008739601.1 556571176 17448970 complement(9030572..9031477) 1 NC_022657.1 COG0294 Dihydropteroate synthase and related enzymes; putative dihydropteroate synthase 9031477 17448970 AFR_41470 Actinoplanes friuliensis DSM 7358 putative dihydropteroate synthase YP_008739601.1 9030572 R 1246995 CDS YP_008739602.1 556571177 17448971 9031789..9032082 1 NC_022657.1 hypothetical protein 9032082 17448971 AFR_41475 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739602.1 9031789 D 1246995 CDS YP_008739603.1 556571178 17448972 9032099..9032461 1 NC_022657.1 hypothetical protein 9032461 17448972 AFR_41480 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739603.1 9032099 D 1246995 CDS YP_008739604.1 556571179 17448973 9032574..9036020 1 NC_022657.1 COG0433 Predicted ATPase; hypothetical protein 9036020 17448973 AFR_41485 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739604.1 9032574 D 1246995 CDS YP_008739605.1 556571180 17448974 9036043..9037983 1 NC_022657.1 hypothetical protein 9037983 17448974 AFR_41490 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739605.1 9036043 D 1246995 CDS YP_008739606.1 556571181 17448975 9037990..9038541 1 NC_022657.1 hypothetical protein 9038541 17448975 AFR_41495 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739606.1 9037990 D 1246995 CDS YP_008739607.1 556571182 17448976 9038562..9039677 1 NC_022657.1 COG0739 Membrane proteins related to metalloendopeptidases; Morphogenesis protein 1 9039677 17448976 AFR_41500 Actinoplanes friuliensis DSM 7358 Morphogenesis protein 1 YP_008739607.1 9038562 D 1246995 CDS YP_008739608.1 556571183 17448977 9039800..9040276 1 NC_022657.1 hypothetical protein 9040276 17448977 AFR_41505 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739608.1 9039800 D 1246995 CDS YP_008739609.1 556571184 17448978 complement(9040281..9040703) 1 NC_022657.1 hypothetical protein 9040703 17448978 AFR_41510 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739609.1 9040281 R 1246995 CDS YP_008739610.1 556571185 17448979 9040975..9043560 1 NC_022657.1 COG1674 DNA segregation ATPase FtsK/SpoIIIE and related proteins; putative FtsK/SpoIIIE family protein 9043560 17448979 AFR_41515 Actinoplanes friuliensis DSM 7358 putative FtsK/SpoIIIE family protein YP_008739610.1 9040975 D 1246995 CDS YP_008739611.1 556571186 17448980 9043557..9044195 1 NC_022657.1 hypothetical protein 9044195 17448980 AFR_41520 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739611.1 9043557 D 1246995 CDS YP_008739612.1 556571187 17448981 9044211..9044471 1 NC_022657.1 hypothetical protein 9044471 17448981 AFR_41525 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739612.1 9044211 D 1246995 CDS YP_008739613.1 556571188 17448982 complement(9044468..9044878) 1 NC_022657.1 COG0251 Putative translation initiation inhibitor, yjgF family; hypothetical protein 9044878 17448982 AFR_41530 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739613.1 9044468 R 1246995 CDS YP_008739614.1 556571189 17448983 complement(9044907..9045353) 1 NC_022657.1 COG0302 GTP cyclohydrolase I; putative GTP cyclohydrolase I 9045353 17448983 AFR_41535 Actinoplanes friuliensis DSM 7358 putative GTP cyclohydrolase I YP_008739614.1 9044907 R 1246995 CDS YP_008739615.1 556571190 17448984 complement(9045575..9047608) 1 NC_022657.1 COG0465 ATP-dependent Zn proteases; cell division protease FtsH 9047608 17448984 AFR_41540 Actinoplanes friuliensis DSM 7358 cell division protease FtsH YP_008739615.1 9045575 R 1246995 CDS YP_008739616.1 556571191 17448985 complement(9047990..9048565) 1 NC_022657.1 COG0634 Hypoxanthine-guanine phosphoribosyltransferase; putative hypoxanthine phosphoribosyltransferase 9048565 17448985 AFR_41545 Actinoplanes friuliensis DSM 7358 putative hypoxanthine phosphoribosyltransferase YP_008739616.1 9047990 R 1246995 CDS YP_008739617.1 556571192 17448986 complement(9048693..9049616) 1 NC_022657.1 COG0037 Predicted ATPase of the PP-loop superfamily implicated in cell cycle control; hypothetical protein 9049616 17448986 AFR_41550 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739617.1 9048693 R 1246995 CDS YP_008739618.1 556571193 17448987 complement(9049668..9050726) 1 NC_022657.1 COG5282 Uncharacterized conserved protein; hypothetical protein 9050726 17448987 AFR_41555 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739618.1 9049668 R 1246995 CDS YP_008739619.1 556571194 17448988 complement(9050776..9052140) 1 NC_022657.1 COG2027 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4); D-alanyl-D-alanine carboxypeptidase / D-alanyl-D-alanine-endopeptidase (penicillin-binding protein 4) 9052140 17448988 AFR_41560 Actinoplanes friuliensis DSM 7358 D-alanyl-D-alanine carboxypeptidase / D-alanyl-D-alanine-endopeptidase (penicillin-binding protein 4) YP_008739619.1 9050776 R 1246995 CDS YP_008739620.1 556571195 17448989 9052714..9053217 1 NC_022657.1 COG0221 Inorganic pyrophosphatase; inorganic pyrophosphatase 9053217 17448989 AFR_41565 Actinoplanes friuliensis DSM 7358 inorganic pyrophosphatase YP_008739620.1 9052714 D 1246995 CDS YP_008739621.1 556571196 17448990 complement(9053274..9054704) 1 NC_022657.1 secretion protein snm4 9054704 17448990 AFR_41570 Actinoplanes friuliensis DSM 7358 secretion protein snm4 YP_008739621.1 9053274 R 1246995 CDS YP_008739622.1 556571197 17448991 9054908..9058888 1 NC_022657.1 COG1674 DNA segregation ATPase FtsK/SpoIIIE and related proteins; cell division protein ftsk/spoiiie 9058888 17448991 AFR_41575 Actinoplanes friuliensis DSM 7358 cell division protein ftsk/spoiiie YP_008739622.1 9054908 D 1246995 CDS YP_008739623.1 556571198 17448992 9059100..9060407 1 NC_022657.1 COG1404 Subtilisin-like serine proteases; peptidase S8/S53 subtilisin kexin sedolisin 9060407 17448992 AFR_41580 Actinoplanes friuliensis DSM 7358 peptidase S8/S53 subtilisin kexin sedolisin YP_008739623.1 9059100 D 1246995 CDS YP_008739624.1 556571199 17448993 complement(9061304..9062476) 1 NC_022657.1 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain; putative serine protease 9062476 17448993 AFR_41585 Actinoplanes friuliensis DSM 7358 putative serine protease YP_008739624.1 9061304 R 1246995 CDS YP_008739625.1 556571200 17448994 complement(9062505..9063188) 1 NC_022657.1 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; hypothetical protein 9063188 17448994 AFR_41590 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739625.1 9062505 R 1246995 CDS YP_008739626.1 556571201 17448995 complement(9063185..9063898) 1 NC_022657.1 COG0526 Thiol-disulfide isomerase and thioredoxins; Thiol:disulfide interchange protein dsbE 9063898 17448995 AFR_41595 Actinoplanes friuliensis DSM 7358 Thiol:disulfide interchange protein dsbE YP_008739626.1 9063185 R 1246995 CDS YP_008739627.1 556571202 17448996 complement(9063952..9064788) 1 NC_022657.1 COG0177 Predicted EndoIII-related endonuclease; endonuclease III 9064788 17448996 AFR_41600 Actinoplanes friuliensis DSM 7358 endonuclease III YP_008739627.1 9063952 R 1246995 CDS YP_008739628.1 556571203 17448997 complement(9064837..9066069) 1 NC_022657.1 COG2843 Putative enzyme of poly-gamma-glutamate biosynthesis (capsule formation); putative capsule synthesis protein 9066069 17448997 AFR_41605 Actinoplanes friuliensis DSM 7358 putative capsule synthesis protein YP_008739628.1 9064837 R 1246995 CDS YP_008739629.1 556571204 17448998 9066216..9066893 1 NC_022657.1 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases; Regulatory protein hlyX 9066893 17448998 AFR_41610 Actinoplanes friuliensis DSM 7358 Regulatory protein hlyX YP_008739629.1 9066216 D 1246995 CDS YP_008739630.1 556571205 17448999 9067109..9068560 1 NC_022657.1 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta); putative acetyl/propionyl-CoA carboxylase beta subunit 9068560 17448999 AFR_41615 Actinoplanes friuliensis DSM 7358 putative acetyl/propionyl-CoA carboxylase beta subunit YP_008739630.1 9067109 D 1246995 CDS YP_008739631.1 556571206 17449000 9068581..9070587 1 NC_022657.1 COG0439 Biotin carboxylase; propionyl-CoA carboxylase subunit alpha 9070587 17449000 AFR_41620 Actinoplanes friuliensis DSM 7358 propionyl-CoA carboxylase subunit alpha YP_008739631.1 9068581 D 1246995 CDS YP_008739632.1 556571207 17449001 complement(9070588..9072051) 1 NC_022657.1 COG0515 Serine/threonine protein kinase; protein kinase 9072051 17449001 AFR_41625 Actinoplanes friuliensis DSM 7358 protein kinase YP_008739632.1 9070588 R 1246995 CDS YP_008739633.1 556571208 17449002 complement(9072131..9075763) 1 NC_022657.1 COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain); putative adenylate/guanylate cyclase 9075763 17449002 AFR_41630 Actinoplanes friuliensis DSM 7358 putative adenylate/guanylate cyclase YP_008739633.1 9072131 R 1246995 CDS YP_008739634.1 556571209 17449003 complement(9075772..9076575) 1 NC_022657.1 COG0491 Zn-dependent hydrolases, including glyoxylases; beta-lactamase 9076575 17449003 AFR_41635 Actinoplanes friuliensis DSM 7358 beta-lactamase YP_008739634.1 9075772 R 1246995 CDS YP_008739635.1 556571210 17449004 complement(9076681..9077172) 1 NC_022657.1 COG0251 Putative translation initiation inhibitor, yjgF family; hypothetical protein 9077172 17449004 AFR_41640 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739635.1 9076681 R 1246995 CDS YP_008739636.1 556571211 17449005 complement(9077169..9077324) 1 NC_022657.1 hypothetical protein 9077324 17449005 AFR_41645 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739636.1 9077169 R 1246995 CDS YP_008739637.1 556571212 17449006 9077481..9078359 1 NC_022657.1 hypothetical protein 9078359 17449006 AFR_41650 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739637.1 9077481 D 1246995 CDS YP_008739638.1 556571213 17449007 9078419..9079333 1 NC_022657.1 COG0003 Oxyanion-translocating ATPase; anion-transporting ATPase 9079333 17449007 AFR_41655 Actinoplanes friuliensis DSM 7358 anion-transporting ATPase YP_008739638.1 9078419 D 1246995 CDS YP_008739639.1 556571214 17449008 9079395..9080534 1 NC_022657.1 COG0003 Oxyanion-translocating ATPase; putative anion-transporting ATPase 9080534 17449008 AFR_41660 Actinoplanes friuliensis DSM 7358 putative anion-transporting ATPase YP_008739639.1 9079395 D 1246995 CDS YP_008739640.1 556571215 17449009 complement(9080542..9080838) 1 NC_022657.1 transcription factor WhiB 9080838 17449009 AFR_41665 Actinoplanes friuliensis DSM 7358 transcription factor WhiB YP_008739640.1 9080542 R 1246995 CDS YP_008739641.1 556571216 17449010 9081157..9083556 1 NC_022657.1 COG0744 Membrane carboxypeptidase (penicillin-binding protein); putative glycosyltransferase 9083556 17449010 AFR_41670 Actinoplanes friuliensis DSM 7358 putative glycosyltransferase YP_008739641.1 9081157 D 1246995 CDS YP_008739642.1 556571217 17449011 complement(9083604..9084056) 1 NC_022657.1 COG1610 Uncharacterized conserved protein; GatB/YqeY domain-containing protein 9084056 17449011 AFR_41675 Actinoplanes friuliensis DSM 7358 GatB/YqeY domain-containing protein YP_008739642.1 9083604 R 1246995 CDS YP_008739643.1 556571218 17449012 9084082..9084975 1 NC_022657.1 COG1408 Predicted phosphohydrolases; putative metallophosphoesterase 9084975 17449012 AFR_41680 Actinoplanes friuliensis DSM 7358 putative metallophosphoesterase YP_008739643.1 9084082 D 1246995 CDS YP_008739644.1 556571219 17449014 complement(9085522..9085740) 1 NC_022657.1 hypothetical protein 9085740 17449014 AFR_41685 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739644.1 9085522 R 1246995 CDS YP_008739645.1 556571220 17449015 complement(9085932..9086270) 1 NC_022657.1 hypothetical protein 9086270 17449015 AFR_41690 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739645.1 9085932 R 1246995 CDS YP_008739646.1 556571221 17449016 complement(9086306..9087505) 1 NC_022657.1 COG0477 Permeases of the major facilitator superfamily; putative MFS transporter 9087505 17449016 AFR_41695 Actinoplanes friuliensis DSM 7358 putative MFS transporter YP_008739646.1 9086306 R 1246995 CDS YP_008739647.1 556571222 17449017 complement(9087502..9088050) 1 NC_022657.1 COG0640 Predicted transcriptional regulators; ArsR family transcriptional regulator 9088050 17449017 AFR_41700 Actinoplanes friuliensis DSM 7358 ArsR family transcriptional regulator YP_008739647.1 9087502 R 1246995 CDS YP_008739648.1 556571223 17449018 complement(9088147..9088626) 1 NC_022657.1 COG0461 Orotate phosphoribosyltransferase; orotate phosphoribosyltransferase 9088626 17449018 AFR_41705 Actinoplanes friuliensis DSM 7358 orotate phosphoribosyltransferase YP_008739648.1 9088147 R 1246995 CDS YP_008739649.1 556571224 17449019 9088736..9089896 1 NC_022657.1 COG3287 Uncharacterized conserved protein; hypothetical protein 9089896 17449019 AFR_41710 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739649.1 9088736 D 1246995 CDS YP_008739650.1 556571225 17449020 9089899..9092133 1 NC_022657.1 COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain; putative diguanylate cyclase/phosphodiesterase with GAF sensor 9092133 17449020 AFR_41715 Actinoplanes friuliensis DSM 7358 putative diguanylate cyclase/phosphodiesterase with GAF sensor YP_008739650.1 9089899 D 1246995 CDS YP_008739651.1 556571226 17449021 9092239..9092535 1 NC_022657.1 hypothetical protein 9092535 17449021 AFR_41720 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739651.1 9092239 D 1246995 CDS YP_008739652.1 556571227 17449022 complement(9092588..9093697) 1 NC_022657.1 COG3979 Uncharacterized protein contain chitin-binding domain type 3; putative chitinase 9093697 17449022 AFR_41725 Actinoplanes friuliensis DSM 7358 putative chitinase YP_008739652.1 9092588 R 1246995 CDS YP_008739653.1 556571228 17449023 9093898..9095199 1 NC_022657.1 COG0840 Methyl-accepting chemotaxis protein; Methyl-accepting chemotaxis protein 4 9095199 17449023 AFR_41730 Actinoplanes friuliensis DSM 7358 Methyl-accepting chemotaxis protein 4 YP_008739653.1 9093898 D 1246995 CDS YP_008739654.1 556571229 17449024 9095800..9096537 1 NC_022657.1 hypothetical protein 9096537 17449024 AFR_41735 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739654.1 9095800 D 1246995 CDS YP_008739655.1 556571230 17449025 complement(9096643..9097713) 1 NC_022657.1 COG0136 Aspartate-semialdehyde dehydrogenase; aspartate-semialdehyde dehydrogenase 9097713 17449025 AFR_41740 Actinoplanes friuliensis DSM 7358 aspartate-semialdehyde dehydrogenase YP_008739655.1 9096643 R 1246995 CDS YP_008739656.1 556571231 17449026 complement(9097721..9098986) 1 NC_022657.1 COG0527 Aspartokinases; aspartate kinase 9098986 17449026 AFR_41745 Actinoplanes friuliensis DSM 7358 aspartate kinase YP_008739656.1 9097721 R 1246995 CDS YP_008739657.1 556571232 17449027 9099210..9100019 1 NC_022657.1 hypothetical protein 9100019 17449027 AFR_41750 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739657.1 9099210 D 1246995 CDS YP_008739658.1 556571233 17449028 9100275..9101963 1 NC_022657.1 COG0119 Isopropylmalate/homocitrate/citramalate synthases; 2-isopropylmalate synthase 9101963 17449028 AFR_41755 Actinoplanes friuliensis DSM 7358 2-isopropylmalate synthase YP_008739658.1 9100275 D 1246995 CDS YP_008739659.1 556571234 17449029 9102070..9102732 1 NC_022657.1 COG3513 Uncharacterized protein conserved in bacteria; hypothetical protein 9102732 17449029 AFR_41760 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739659.1 9102070 D 1246995 CDS YP_008739660.1 556571235 17449030 9102981..9103184 1 NC_022657.1 hypothetical protein 9103184 17449030 AFR_41765 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739660.1 9102981 D 1246995 CDS YP_008739661.1 556571236 17449031 9103258..9104832 1 NC_022657.1 COG3525 N-acetyl-beta-hexosaminidase; N-acetyl-beta-hexosaminidase 9104832 17449031 AFR_41770 Actinoplanes friuliensis DSM 7358 N-acetyl-beta-hexosaminidase YP_008739661.1 9103258 D 1246995 CDS YP_008739662.1 556571237 17449032 complement(9105525..9106562) 1 NC_022657.1 COG4608 ABC-type oligopeptide transport system, ATPase component; putative peptide ABC transporter ATP-binding protein 9106562 17449032 AFR_41775 Actinoplanes friuliensis DSM 7358 putative peptide ABC transporter ATP-binding protein YP_008739662.1 9105525 R 1246995 CDS YP_008739663.1 556571238 17449033 complement(9106580..9107644) 1 NC_022657.1 COG0444 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component; phosphate import ATP-binding protein pstB 9107644 17449033 AFR_41780 Actinoplanes friuliensis DSM 7358 phosphate import ATP-binding protein pstB YP_008739663.1 9106580 R 1246995 CDS YP_008739664.1 556571239 17449034 complement(9107657..9108655) 1 NC_022657.1 COG0601 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components; ABC transporter permease 9108655 17449034 AFR_41785 Actinoplanes friuliensis DSM 7358 ABC transporter permease YP_008739664.1 9107657 R 1246995 CDS YP_008739665.1 556571240 17449035 complement(9108778..9110553) 1 NC_022657.1 COG0747 ABC-type dipeptide transport system, periplasmic component; putative ABC transporter substrate-binding protein 9110553 17449035 AFR_41790 Actinoplanes friuliensis DSM 7358 putative ABC transporter substrate-binding protein YP_008739665.1 9108778 R 1246995 CDS YP_008739666.1 556571241 17449036 complement(9110635..9111642) 1 NC_022657.1 COG1173 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components; ABC transporter permease 9111642 17449036 AFR_41795 Actinoplanes friuliensis DSM 7358 ABC transporter permease YP_008739666.1 9110635 R 1246995 CDS YP_008739667.1 556571242 17449037 complement(9112002..9112595) 1 NC_022657.1 COG0353 Recombinational DNA repair protein (RecF pathway); putative recombination and repair protein 9112595 17449037 AFR_41800 Actinoplanes friuliensis DSM 7358 putative recombination and repair protein YP_008739667.1 9112002 R 1246995 CDS YP_008739668.1 556571243 17449038 complement(9112600..9112932) 1 NC_022657.1 COG0718 Uncharacterized protein conserved in bacteria; hypothetical protein 9112932 17449038 AFR_41805 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739668.1 9112600 R 1246995 CDS YP_008739669.1 556571244 17449039 complement(9113004..9116552) 1 NC_022657.1 COG2812 DNA polymerase III, gamma/tau subunits; DNA polymerase III subunits gamma and tau 9116552 17449039 AFR_41810 Actinoplanes friuliensis DSM 7358 DNA polymerase III subunits gamma and tau YP_008739669.1 9113004 R 1246995 CDS YP_008739670.1 556571245 17449041 complement(9116962..9117807) 1 NC_022657.1 hypothetical protein 9117807 17449041 AFR_41815 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739670.1 9116962 R 1246995 CDS YP_008739671.1 556571246 17449042 9117891..9118121 1 NC_022657.1 hypothetical protein 9118121 17449042 AFR_41820 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739671.1 9117891 D 1246995 CDS YP_008739672.1 556571247 17449043 complement(9118129..9118653) 1 NC_022657.1 hypothetical protein 9118653 17449043 AFR_41825 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739672.1 9118129 R 1246995 CDS YP_008739673.1 556571248 17449044 complement(9118650..9119852) 1 NC_022657.1 COG0477 Permeases of the major facilitator superfamily; major facilitator superfamily protein 9119852 17449044 AFR_41830 Actinoplanes friuliensis DSM 7358 major facilitator superfamily protein YP_008739673.1 9118650 R 1246995 CDS YP_008739674.1 556571249 17449045 complement(9119849..9120451) 1 NC_022657.1 COG0640 Predicted transcriptional regulators; ArsR family transcriptional regulator 9120451 17449045 AFR_41835 Actinoplanes friuliensis DSM 7358 ArsR family transcriptional regulator YP_008739674.1 9119849 R 1246995 CDS YP_008739675.1 556571250 17449046 complement(9120496..9120837) 1 NC_022657.1 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); hypothetical protein 9120837 17449046 AFR_41840 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739675.1 9120496 R 1246995 CDS YP_008739676.1 556571251 17449047 complement(9120922..9121446) 1 NC_022657.1 hypothetical protein 9121446 17449047 AFR_41845 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739676.1 9120922 R 1246995 CDS YP_008739677.1 556571252 17449048 complement(9121556..9121765) 1 NC_022657.1 hypothetical protein 9121765 17449048 AFR_41850 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739677.1 9121556 R 1246995 CDS YP_008739678.1 556571253 17449049 complement(9121994..9122467) 1 NC_022657.1 UspA domain-containing protein 9122467 17449049 AFR_41855 Actinoplanes friuliensis DSM 7358 UspA domain-containing protein YP_008739678.1 9121994 R 1246995 CDS YP_008739679.1 556571254 17449050 complement(9122464..9123690) 1 NC_022657.1 COG1055 Na+/H+ antiporter NhaD and related arsenite permeases; arsenical pump membrane protein 9123690 17449050 AFR_41860 Actinoplanes friuliensis DSM 7358 arsenical pump membrane protein YP_008739679.1 9122464 R 1246995 CDS YP_008739680.1 556571255 17449051 9123832..9124140 1 NC_022657.1 COG0695 Glutaredoxin and related proteins; integral membrane protein 9124140 17449051 AFR_41865 Actinoplanes friuliensis DSM 7358 integral membrane protein YP_008739680.1 9123832 D 1246995 CDS YP_008739681.1 556571256 17449052 complement(9124070..9124408) 1 NC_022657.1 hypothetical protein 9124408 17449052 AFR_41870 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739681.1 9124070 R 1246995 CDS YP_008739682.1 556571257 17449053 9124540..9124860 1 NC_022657.1 hypothetical protein 9124860 17449053 AFR_41875 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739682.1 9124540 D 1246995 CDS YP_008739683.1 556571258 17449055 9125176..9125883 1 NC_022657.1 COG0813 Purine-nucleoside phosphorylase; purine nucleoside phosphorylase 9125883 deoD 17449055 deoD Actinoplanes friuliensis DSM 7358 purine nucleoside phosphorylase YP_008739683.1 9125176 D 1246995 CDS YP_008739684.1 556571259 17449056 complement(9125876..9126325) 1 NC_022657.1 COG0590 Cytosine/adenosine deaminases; putative cytidine/deoxycytidine deaminase 9126325 17449056 AFR_41885 Actinoplanes friuliensis DSM 7358 putative cytidine/deoxycytidine deaminase YP_008739684.1 9125876 R 1246995 CDS YP_008739685.1 556571260 17449057 complement(9126325..9126849) 1 NC_022657.1 hypothetical protein 9126849 17449057 AFR_41890 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739685.1 9126325 R 1246995 CDS YP_008739686.1 556571261 17449058 complement(9126950..9127153) 1 NC_022657.1 hypothetical protein 9127153 17449058 AFR_41895 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739686.1 9126950 R 1246995 CDS YP_008739687.1 556571262 17449059 complement(9127221..9127631) 1 NC_022657.1 hypothetical protein 9127631 17449059 AFR_41900 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739687.1 9127221 R 1246995 CDS YP_008739688.1 556571263 17449060 9127686..9128462 1 NC_022657.1 COG0739 Membrane proteins related to metalloendopeptidases; putative M23-family peptidase 9128462 17449060 AFR_41905 Actinoplanes friuliensis DSM 7358 putative M23-family peptidase YP_008739688.1 9127686 D 1246995 CDS YP_008739689.1 556571264 17449061 complement(9128524..9129666) 1 NC_022657.1 hypothetical protein 9129666 17449061 AFR_41910 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739689.1 9128524 R 1246995 CDS YP_008739690.1 556571265 17449062 9129771..9130763 1 NC_022657.1 COG0287 Prephenate dehydrogenase; prephenate dehydrogenase 9130763 17449062 AFR_41915 Actinoplanes friuliensis DSM 7358 prephenate dehydrogenase YP_008739690.1 9129771 D 1246995 CDS YP_008739691.1 556571266 17449063 9130822..9131394 1 NC_022657.1 hypothetical protein 9131394 17449063 AFR_41920 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739691.1 9130822 D 1246995 CDS YP_008739692.1 556571267 17449064 complement(9131391..9132353) 1 NC_022657.1 COG0182 Predicted translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family; putative initiation factor eIF-2B alpha subunit 9132353 17449064 AFR_41925 Actinoplanes friuliensis DSM 7358 putative initiation factor eIF-2B alpha subunit YP_008739692.1 9131391 R 1246995 CDS YP_008739693.1 556571268 17449065 9132426..9133502 1 NC_022657.1 COG1387 Histidinol phosphatase and related hydrolases of the PHP family; hypothetical protein 9133502 17449065 AFR_41930 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739693.1 9132426 D 1246995 CDS YP_008739694.1 556571269 17449066 9133512..9135182 1 NC_022657.1 COG4805 Uncharacterized protein conserved in bacteria; hypothetical protein 9135182 17449066 AFR_41935 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739694.1 9133512 D 1246995 CDS YP_008739695.1 556571270 17449067 9135678..9136820 1 NC_022657.1 hypothetical protein 9136820 17449067 AFR_41940 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739695.1 9135678 D 1246995 CDS YP_008739696.1 556571271 17449068 9136807..9139584 1 NC_022657.1 COG0642 Signal transduction histidine kinase; putative sensor-like histidine kinase 9139584 17449068 AFR_41945 Actinoplanes friuliensis DSM 7358 putative sensor-like histidine kinase YP_008739696.1 9136807 D 1246995 CDS YP_008739697.1 556571272 17449069 9139581..9140051 1 NC_022657.1 COG2018 Uncharacterized distant relative of homeotic protein bithoraxoid; hypothetical protein 9140051 17449069 AFR_41950 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739697.1 9139581 D 1246995 CDS YP_008739698.1 556571273 17449070 9140048..9140515 1 NC_022657.1 COG1064 Zn-dependent alcohol dehydrogenases; hypothetical protein 9140515 17449070 AFR_41955 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739698.1 9140048 D 1246995 CDS YP_008739699.1 556571274 17449071 9140574..9141125 1 NC_022657.1 COG2229 Predicted GTPase; putative ATP/GTP-binding protein 9141125 17449071 AFR_41960 Actinoplanes friuliensis DSM 7358 putative ATP/GTP-binding protein YP_008739699.1 9140574 D 1246995 CDS YP_008739700.1 556571275 17449072 9141221..9141949 1 NC_022657.1 hypothetical protein 9141949 17449072 AFR_41965 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739700.1 9141221 D 1246995 CDS YP_008739701.1 556571276 17449073 complement(9142555..9147426) 1 NC_022657.1 COG1222 ATP-dependent 26S proteasome regulatory subunit; hypothetical protein 9147426 17449073 AFR_41970 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739701.1 9142555 R 1246995 CDS YP_008739702.1 556571277 17449074 complement(9147423..9149462) 1 NC_022657.1 COG2268 Uncharacterized protein conserved in bacteria; hypothetical protein 9149462 17449074 AFR_41975 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739702.1 9147423 R 1246995 CDS YP_008739703.1 556571278 17449075 complement(9149483..9150073) 1 NC_022657.1 hypothetical protein 9150073 17449075 AFR_41980 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739703.1 9149483 R 1246995 CDS YP_008739704.1 556571279 17449076 9150530..9151876 1 NC_022657.1 COG1215 Glycosyltransferases, probably involved in cell wall biogenesis; N-acetyl-glucosamine transferase 9151876 17449076 AFR_41985 Actinoplanes friuliensis DSM 7358 N-acetyl-glucosamine transferase YP_008739704.1 9150530 D 1246995 CDS YP_008739705.1 556571280 17449077 9151909..9153105 1 NC_022657.1 COG0381 UDP-N-acetylglucosamine 2-epimerase; UDP-N-acetylglucosamine 2-epimerase 9153105 17449077 AFR_41990 Actinoplanes friuliensis DSM 7358 UDP-N-acetylglucosamine 2-epimerase YP_008739705.1 9151909 D 1246995 CDS YP_008739706.1 556571281 17449078 9153105..9154742 1 NC_022657.1 COG5298 Uncharacterized protein conserved in bacteria; hypothetical protein 9154742 17449078 AFR_41995 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739706.1 9153105 D 1246995 CDS YP_008739707.1 556571282 17449079 9154810..9155175 1 NC_022657.1 hypothetical protein 9155175 17449079 AFR_42000 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739707.1 9154810 D 1246995 CDS YP_008739708.1 556571283 17449080 complement(9155177..9156925) 1 NC_022657.1 Beta-galactoside-specific lectin 3 9156925 17449080 AFR_42005 Actinoplanes friuliensis DSM 7358 Beta-galactoside-specific lectin 3 YP_008739708.1 9155177 R 1246995 CDS YP_008739709.1 556571284 17449081 complement(9157004..9157756) 1 NC_022657.1 COG0412 Dienelactone hydrolase and related enzymes; carboxymethylenebutenolidase 9157756 17449081 AFR_42010 Actinoplanes friuliensis DSM 7358 carboxymethylenebutenolidase YP_008739709.1 9157004 R 1246995 CDS YP_008739710.1 556571285 17449082 9157932..9159347 1 NC_022657.1 cellulose-binding family II protein 9159347 17449082 AFR_42015 Actinoplanes friuliensis DSM 7358 cellulose-binding family II protein YP_008739710.1 9157932 D 1246995 CDS YP_008739711.1 556571286 17449083 complement(9159436..9160017) 1 NC_022657.1 COG1309 Transcriptional regulator; putative TetR-family transcriptional regulator 9160017 17449083 AFR_42020 Actinoplanes friuliensis DSM 7358 putative TetR-family transcriptional regulator YP_008739711.1 9159436 R 1246995 CDS YP_008739712.1 556571287 17449084 9160144..9160611 1 NC_022657.1 COG1846 Transcriptional regulators; putative MarR-family transcriptional regulator 9160611 17449084 AFR_42025 Actinoplanes friuliensis DSM 7358 putative MarR-family transcriptional regulator YP_008739712.1 9160144 D 1246995 CDS YP_008739713.1 556571288 17449085 9160647..9162206 1 NC_022657.1 COG0477 Permeases of the major facilitator superfamily; putative MFS transporter 9162206 17449085 AFR_42030 Actinoplanes friuliensis DSM 7358 putative MFS transporter YP_008739713.1 9160647 D 1246995 CDS YP_008739714.1 556571289 17449086 complement(9162653..9163126) 1 NC_022657.1 COG0645 Predicted kinase; hypothetical protein 9163126 17449086 AFR_42035 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739714.1 9162653 R 1246995 CDS YP_008739715.1 556571290 17449087 complement(9163701..9165170) 1 NC_022657.1 COG0477 Permeases of the major facilitator superfamily; EmrB/QacA subfamily drug resistance transporter 9165170 17449087 AFR_42040 Actinoplanes friuliensis DSM 7358 EmrB/QacA subfamily drug resistance transporter YP_008739715.1 9163701 R 1246995 CDS YP_008739716.1 556571291 17449088 complement(9165231..9165968) 1 NC_022657.1 COG1309 Transcriptional regulator; TetR family transcriptional regulator 9165968 17449088 AFR_42045 Actinoplanes friuliensis DSM 7358 TetR family transcriptional regulator YP_008739716.1 9165231 R 1246995 CDS YP_008739717.1 556571292 17449089 9166098..9167690 1 NC_022657.1 COG2199 FOG: GGDEF domain; putative diguanylate cyclase 9167690 17449089 AFR_42050 Actinoplanes friuliensis DSM 7358 putative diguanylate cyclase YP_008739717.1 9166098 D 1246995 CDS YP_008739718.1 556571293 17449090 9167800..9168612 1 NC_022657.1 hypothetical protein 9168612 17449090 AFR_42055 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739718.1 9167800 D 1246995 CDS YP_008739719.1 556571294 17449091 complement(9169047..9169409) 1 NC_022657.1 hypothetical protein 9169409 17449091 AFR_42060 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739719.1 9169047 R 1246995 CDS YP_008739720.1 556571295 17449092 complement(9169387..9169617) 1 NC_022657.1 hypothetical protein 9169617 17449092 AFR_42065 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739720.1 9169387 R 1246995 CDS YP_008739721.1 556571296 17449093 9169868..9170104 1 NC_022657.1 hypothetical protein 9170104 17449093 AFR_42070 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739721.1 9169868 D 1246995 CDS YP_008739722.1 556571297 17449094 complement(9170155..9171045) 1 NC_022657.1 putative DNA-binding protein 9171045 17449094 AFR_42075 Actinoplanes friuliensis DSM 7358 putative DNA-binding protein YP_008739722.1 9170155 R 1246995 CDS YP_008739723.1 556571298 17449095 9171317..9171640 1 NC_022657.1 hypothetical protein 9171640 17449095 AFR_42080 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739723.1 9171317 D 1246995 CDS YP_008739724.1 556571299 17449096 9171637..9171825 1 NC_022657.1 hypothetical protein 9171825 17449096 AFR_42085 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739724.1 9171637 D 1246995 CDS YP_008739725.1 556571300 17449097 complement(9171822..9172214) 1 NC_022657.1 COG0251 Putative translation initiation inhibitor, yjgF family; endoribonuclease L-PSP 9172214 17449097 AFR_42090 Actinoplanes friuliensis DSM 7358 endoribonuclease L-PSP YP_008739725.1 9171822 R 1246995 CDS YP_008739726.1 556571301 17449098 complement(9172211..9172945) 1 NC_022657.1 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases; 2-hydroxy-3-oxopropionate reductase 9172945 17449098 AFR_42095 Actinoplanes friuliensis DSM 7358 2-hydroxy-3-oxopropionate reductase YP_008739726.1 9172211 R 1246995 CDS YP_008739727.1 556571302 17449099 9173058..9173945 1 NC_022657.1 COG0583 Transcriptional regulator; putative RuBisCO transcriptional regulator 9173945 17449099 AFR_42100 Actinoplanes friuliensis DSM 7358 putative RuBisCO transcriptional regulator YP_008739727.1 9173058 D 1246995 CDS YP_008739728.1 556571303 17449100 9174002..9174547 1 NC_022657.1 hypothetical protein 9174547 17449100 AFR_42105 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739728.1 9174002 D 1246995 CDS YP_008739729.1 556571304 17449101 complement(9174551..9175387) 1 NC_022657.1 COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; phosphoribosylaminoimidazole-succinocarboxamide synthase 9175387 17449101 AFR_42110 Actinoplanes friuliensis DSM 7358 phosphoribosylaminoimidazole-succinocarboxamide synthase YP_008739729.1 9174551 R 1246995 CDS YP_008739730.1 556571305 17449102 9175506..9178583 1 NC_022657.1 COG3886 Predicted HKD family nuclease; type III restriction protein res subunit 9178583 17449102 AFR_42115 Actinoplanes friuliensis DSM 7358 type III restriction protein res subunit YP_008739730.1 9175506 D 1246995 CDS YP_008739731.1 556571306 17449103 complement(9178587..9179693) 1 NC_022657.1 COG1520 FOG: WD40-like repeat; hypothetical protein 9179693 17449103 AFR_42120 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739731.1 9178587 R 1246995 CDS YP_008739732.1 556571307 17449104 9179913..9184736 1 NC_022657.1 COG2374 Predicted extracellular nuclease; putative 5'-nucleotidase 9184736 17449104 AFR_42125 Actinoplanes friuliensis DSM 7358 putative 5'-nucleotidase YP_008739732.1 9179913 D 1246995 CDS YP_008739733.1 556571308 17449105 9184817..9185641 1 NC_022657.1 hypothetical protein 9185641 17449105 AFR_42130 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739733.1 9184817 D 1246995 CDS YP_008739734.1 556571309 17449106 complement(9185626..9186063) 1 NC_022657.1 hypothetical protein 9186063 17449106 AFR_42135 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739734.1 9185626 R 1246995 CDS YP_008739735.1 556571310 17449107 complement(9186072..9187232) 1 NC_022657.1 coagulation factor 5/8 type domain-containing protein 9187232 17449107 AFR_42140 Actinoplanes friuliensis DSM 7358 coagulation factor 5/8 type domain-containing protein YP_008739735.1 9186072 R 1246995 CDS YP_008739736.1 556571311 17449108 complement(9187377..9188393) 1 NC_022657.1 hypothetical protein 9188393 17449108 AFR_42145 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739736.1 9187377 R 1246995 CDS YP_008739737.1 556571312 17449109 complement(9188390..9189271) 1 NC_022657.1 COG1131 ABC-type multidrug transport system, ATPase component; ABC transporter ATP-binding protein 9189271 17449109 AFR_42150 Actinoplanes friuliensis DSM 7358 ABC transporter ATP-binding protein YP_008739737.1 9188390 R 1246995 CDS YP_008739738.1 556571313 17449110 complement(9189268..9189675) 1 NC_022657.1 COG1725 Predicted transcriptional regulators; GntR family transcriptional regulator 9189675 17449110 AFR_42155 Actinoplanes friuliensis DSM 7358 GntR family transcriptional regulator YP_008739738.1 9189268 R 1246995 CDS YP_008739739.1 556571314 17449111 complement(9189810..9190193) 1 NC_022657.1 regulatory protein merr 9190193 17449111 AFR_42160 Actinoplanes friuliensis DSM 7358 regulatory protein merr YP_008739739.1 9189810 R 1246995 CDS YP_008739740.1 556571315 17449112 9190775..9191425 1 NC_022657.1 hypothetical protein 9191425 17449112 AFR_42165 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739740.1 9190775 D 1246995 CDS YP_008739741.1 556571316 17449114 complement(9191712..9194033) 1 NC_022657.1 COG1396 Predicted transcriptional regulators; XRE family transcriptional regulator 9194033 17449114 AFR_42170 Actinoplanes friuliensis DSM 7358 XRE family transcriptional regulator YP_008739741.1 9191712 R 1246995 CDS YP_008739742.1 556571317 17449116 9195190..9195840 1 NC_022657.1 hypothetical protein 9195840 17449116 AFR_42175 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739742.1 9195190 D 1246995 CDS YP_008739743.1 556571318 17449117 complement(9195827..9196600) 1 NC_022657.1 COG1266 Predicted metal-dependent membrane protease; hypothetical protein 9196600 17449117 AFR_42180 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739743.1 9195827 R 1246995 CDS YP_008739744.1 556571319 17449118 9196758..9197864 1 NC_022657.1 COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases; putative oxidoreductase 9197864 17449118 AFR_42185 Actinoplanes friuliensis DSM 7358 putative oxidoreductase YP_008739744.1 9196758 D 1246995 CDS YP_008739745.1 556571320 17449119 complement(9197861..9199402) 1 NC_022657.1 COG1396 Predicted transcriptional regulators; putative polypeptide deformylase 9199402 17449119 AFR_42190 Actinoplanes friuliensis DSM 7358 putative polypeptide deformylase YP_008739745.1 9197861 R 1246995 CDS YP_008739746.1 556571321 17449120 9199717..9200517 1 NC_022657.1 hypothetical protein 9200517 17449120 AFR_42195 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739746.1 9199717 D 1246995 CDS YP_008739747.1 556571322 17449121 complement(9200528..9202156) 1 NC_022657.1 hypothetical protein 9202156 17449121 AFR_42200 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739747.1 9200528 R 1246995 CDS YP_008739748.1 556571323 17449122 9202761..9203474 1 NC_022657.1 COG0500 SAM-dependent methyltransferases; type 12 methyltransferase 9203474 17449122 AFR_42205 Actinoplanes friuliensis DSM 7358 type 12 methyltransferase YP_008739748.1 9202761 D 1246995 CDS YP_008739749.1 556571324 17449123 complement(9203545..9204075) 1 NC_022657.1 COG1881 Phospholipid-binding protein; putative phospholipid-binding protein 9204075 17449123 AFR_42210 Actinoplanes friuliensis DSM 7358 putative phospholipid-binding protein YP_008739749.1 9203545 R 1246995 CDS YP_008739750.1 556571325 17449124 9204439..9205641 1 NC_022657.1 COG2203 FOG: GAF domain; sensor histidine kinase and response regulator of a two component complex 9205641 17449124 AFR_42215 Actinoplanes friuliensis DSM 7358 sensor histidine kinase and response regulator of a two component complex YP_008739750.1 9204439 D 1246995 CDS YP_008739751.1 556571326 17449125 complement(9205638..9206180) 1 NC_022657.1 hypothetical protein 9206180 17449125 AFR_42220 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739751.1 9205638 R 1246995 CDS YP_008739752.1 556571327 17449126 complement(9206220..9206861) 1 NC_022657.1 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins; GCN5-like N-acetyltransferase 9206861 17449126 AFR_42225 Actinoplanes friuliensis DSM 7358 GCN5-like N-acetyltransferase YP_008739752.1 9206220 R 1246995 CDS YP_008739753.1 556571328 17449127 complement(9206907..9207611) 1 NC_022657.1 COG0791 Cell wall-associated hydrolases (invasion-associated proteins); Gamma-DL-glutamyl hydrolase 9207611 17449127 AFR_42230 Actinoplanes friuliensis DSM 7358 Gamma-DL-glutamyl hydrolase YP_008739753.1 9206907 R 1246995 CDS YP_008739754.1 556571329 17449128 9207949..9208290 1 NC_022657.1 COG3795 Uncharacterized protein conserved in bacteria; DGPFAETKE family protein 9208290 17449128 AFR_42235 Actinoplanes friuliensis DSM 7358 DGPFAETKE family protein YP_008739754.1 9207949 D 1246995 CDS YP_008739755.1 556571330 17449129 9208323..9209468 1 NC_022657.1 COG4941 Predicted RNA polymerase sigma factor containing a TPR repeat domain; putative ECF subfamily RNA polymerase sigma-24 subunit 9209468 17449129 AFR_42240 Actinoplanes friuliensis DSM 7358 putative ECF subfamily RNA polymerase sigma-24 subunit YP_008739755.1 9208323 D 1246995 CDS YP_008739756.1 556571331 17449130 complement(9209452..9210207) 1 NC_022657.1 COG4295 Uncharacterized protein conserved in bacteria; hypothetical protein 9210207 17449130 AFR_42245 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739756.1 9209452 R 1246995 CDS YP_008739757.1 556571332 17449131 9210275..9211369 1 NC_022657.1 COG1960 Acyl-CoA dehydrogenases; hydroxylase 9211369 17449131 AFR_42250 Actinoplanes friuliensis DSM 7358 hydroxylase YP_008739757.1 9210275 D 1246995 CDS YP_008739758.1 556571333 17449132 complement(9211366..9211959) 1 NC_022657.1 hypothetical protein 9211959 17449132 AFR_42255 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739758.1 9211366 R 1246995 CDS YP_008739759.1 556571334 17449133 complement(9211971..9212483) 1 NC_022657.1 COG0431 Predicted flavoprotein; NADPH-dependent FMN reductase 9212483 17449133 AFR_42260 Actinoplanes friuliensis DSM 7358 NADPH-dependent FMN reductase YP_008739759.1 9211971 R 1246995 CDS YP_008739760.1 556571335 17449134 9212583..9213011 1 NC_022657.1 COG0789 Predicted transcriptional regulators; MerR family transcriptional regulator 9213011 17449134 AFR_42265 Actinoplanes friuliensis DSM 7358 MerR family transcriptional regulator YP_008739760.1 9212583 D 1246995 CDS YP_008739761.1 556571336 17449135 9213040..9213357 1 NC_022657.1 COG1695 Predicted transcriptional regulators; PadR-like family transcriptional regulator 9213357 17449135 AFR_42270 Actinoplanes friuliensis DSM 7358 PadR-like family transcriptional regulator YP_008739761.1 9213040 D 1246995 CDS YP_008739762.1 556571337 17449136 9213354..9214214 1 NC_022657.1 hypothetical protein 9214214 17449136 AFR_42275 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739762.1 9213354 D 1246995 CDS YP_008739763.1 556571338 17449137 9214259..9214606 1 NC_022657.1 COG1695 Predicted transcriptional regulators; hypothetical protein 9214606 17449137 AFR_42280 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739763.1 9214259 D 1246995 CDS YP_008739764.1 556571339 17449138 9214603..9215136 1 NC_022657.1 COG0103 Ribosomal protein S9; hypothetical protein 9215136 17449138 AFR_42285 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739764.1 9214603 D 1246995 CDS YP_008739765.1 556571340 17449139 complement(9215436..9217013) 1 NC_022657.1 COG3593 Predicted ATP-dependent endonuclease of the OLD family; hypothetical protein 9217013 17449139 AFR_42290 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739765.1 9215436 R 1246995 CDS YP_008739766.1 556571341 17449141 complement(9217583..9218443) 1 NC_022657.1 hypothetical protein 9218443 17449141 AFR_42295 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739766.1 9217583 R 1246995 CDS YP_008739767.1 556571342 17449144 9219036..9220889 1 NC_022657.1 COG5520 O-Glycosyl hydrolase; glycosyl hydrolase 9220889 17449144 AFR_42300 Actinoplanes friuliensis DSM 7358 glycosyl hydrolase YP_008739767.1 9219036 D 1246995 CDS YP_008739768.1 556571343 17449145 9220922..9222274 1 NC_022657.1 COG3469 Chitinase; cellulose-binding family II protein 9222274 17449145 AFR_42305 Actinoplanes friuliensis DSM 7358 cellulose-binding family II protein YP_008739768.1 9220922 D 1246995 CDS YP_008739769.1 556571344 17449146 9222366..9223331 1 NC_022657.1 COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases; putative alcohol dehydrogenase 9223331 17449146 AFR_42310 Actinoplanes friuliensis DSM 7358 putative alcohol dehydrogenase YP_008739769.1 9222366 D 1246995 CDS YP_008739770.1 556571345 17449147 9223449..9224108 1 NC_022657.1 hypothetical protein 9224108 17449147 AFR_42315 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739770.1 9223449 D 1246995 CDS YP_008739771.1 556571346 17449148 9224520..9224969 1 NC_022657.1 hypothetical protein 9224969 17449148 AFR_42320 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739771.1 9224520 D 1246995 CDS YP_008739772.1 556571347 17449149 complement(9225031..9225261) 1 NC_022657.1 hypothetical protein 9225261 17449149 AFR_42325 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739772.1 9225031 R 1246995 CDS YP_008739773.1 556571348 17449150 complement(9225258..9225698) 1 NC_022657.1 COG0789 Predicted transcriptional regulators; Redox-sensitive transcriptional activator SoxR 9225698 17449150 AFR_42330 Actinoplanes friuliensis DSM 7358 Redox-sensitive transcriptional activator SoxR YP_008739773.1 9225258 R 1246995 CDS YP_008739774.1 556571349 17449151 9225732..9226427 1 NC_022657.1 COG3959 Transketolase, N-terminal subunit; putative transketolase 9226427 17449151 AFR_42335 Actinoplanes friuliensis DSM 7358 putative transketolase YP_008739774.1 9225732 D 1246995 CDS YP_008739775.1 556571350 17449152 9226433..9227311 1 NC_022657.1 COG3958 Transketolase, C-terminal subunit; transketolase 9227311 17449152 AFR_42340 Actinoplanes friuliensis DSM 7358 transketolase YP_008739775.1 9226433 D 1246995 CDS YP_008739776.1 556571351 17449153 9227503..9228387 1 NC_022657.1 COG2801 Transposase and inactivated derivatives; Integrase catalytic domain-containing protein 9228387 17449153 AFR_42345 Actinoplanes friuliensis DSM 7358 Integrase catalytic domain-containing protein YP_008739776.1 9227503 D 1246995 CDS YP_008739777.1 556571352 17449154 complement(9228384..9228833) 1 NC_022657.1 hypothetical protein 9228833 17449154 AFR_42350 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739777.1 9228384 R 1246995 CDS YP_008739778.1 556571353 17449155 complement(9228892..9230022) 1 NC_022657.1 COG0183 Acetyl-CoA acetyltransferase; acetyl-CoA acetyltransferase 9230022 17449155 AFR_42355 Actinoplanes friuliensis DSM 7358 acetyl-CoA acetyltransferase YP_008739778.1 9228892 R 1246995 CDS YP_008739779.1 556571354 17449156 9230081..9230482 1 NC_022657.1 hypothetical protein 9230482 17449156 AFR_42360 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739779.1 9230081 D 1246995 CDS YP_008739780.1 556571355 17449157 complement(9230489..9231385) 1 NC_022657.1 COG0705 Uncharacterized membrane protein (homolog of Drosophila rhomboid); rhomboid family protein 9231385 17449157 AFR_42365 Actinoplanes friuliensis DSM 7358 rhomboid family protein YP_008739780.1 9230489 R 1246995 CDS YP_008739781.1 556571356 17449158 complement(9231427..9231957) 1 NC_022657.1 COG0652 Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family; peptidyl-prolyl cis-trans isomerase A 9231957 17449158 AFR_42370 Actinoplanes friuliensis DSM 7358 peptidyl-prolyl cis-trans isomerase A YP_008739781.1 9231427 R 1246995 CDS YP_008739782.1 556571357 17449159 9232126..9232803 1 NC_022657.1 hypothetical protein 9232803 17449159 AFR_42375 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739782.1 9232126 D 1246995 CDS YP_008739783.1 556571358 17449160 complement(9232858..9234303) 1 NC_022657.1 hypothetical protein 9234303 17449160 AFR_42380 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739783.1 9232858 R 1246995 CDS YP_008739784.1 556571359 17449161 complement(9234368..9235426) 1 NC_022657.1 COG0598 Mg2+ and Co2+ transporters; putative metal ion transport protein 9235426 17449161 AFR_42385 Actinoplanes friuliensis DSM 7358 putative metal ion transport protein YP_008739784.1 9234368 R 1246995 CDS YP_008739785.1 556571360 17449162 complement(9235818..9236912) 1 NC_022657.1 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs; GntR family transcriptional regulator 9236912 17449162 AFR_42390 Actinoplanes friuliensis DSM 7358 GntR family transcriptional regulator YP_008739785.1 9235818 R 1246995 CDS YP_008739786.1 556571361 17449163 9237133..9237864 1 NC_022657.1 COG1213 Predicted sugar nucleotidyltransferases; putative nucleotide sugar-1-phosphate transferase 9237864 17449163 AFR_42395 Actinoplanes friuliensis DSM 7358 putative nucleotide sugar-1-phosphate transferase YP_008739786.1 9237133 D 1246995 CDS YP_008739787.1 556571362 17449164 9237852..9238913 1 NC_022657.1 COG0371 Glycerol dehydrogenase and related enzymes; putative glycerol 1-phosphate dehydrogenase 9238913 17449164 AFR_42400 Actinoplanes friuliensis DSM 7358 putative glycerol 1-phosphate dehydrogenase YP_008739787.1 9237852 D 1246995 CDS YP_008739788.1 556571363 17449165 9238888..9239625 1 NC_022657.1 COG0558 Phosphatidylglycerophosphate synthase; putative CDP-alcohol phosphatidyltransferase 9239625 17449165 AFR_42405 Actinoplanes friuliensis DSM 7358 putative CDP-alcohol phosphatidyltransferase YP_008739788.1 9238888 D 1246995 CDS YP_008739789.1 556571364 17449166 complement(9240616..9242136) 1 NC_022657.1 hypothetical protein 9242136 17449166 AFR_42410 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739789.1 9240616 R 1246995 CDS YP_008739790.1 556571365 17449167 complement(9242167..9243444) 1 NC_022657.1 COG0438 Glycosyltransferase; Glycogen synthase 9243444 17449167 AFR_42415 Actinoplanes friuliensis DSM 7358 Glycogen synthase YP_008739790.1 9242167 R 1246995 CDS YP_008739791.1 556571366 17449168 9243382..9244242 1 NC_022657.1 COG0266 Formamidopyrimidine-DNA glycosylase; DNA-formamidopyrimidine glycosylase 9244242 17449168 AFR_42420 Actinoplanes friuliensis DSM 7358 DNA-formamidopyrimidine glycosylase YP_008739791.1 9243382 D 1246995 CDS YP_008739792.1 556571367 17449169 9244497..9245996 1 NC_022657.1 COG2148 Sugar transferases involved in lipopolysaccharide synthesis; undecaprenyl-phosphate galactose phosphotransferase 9245996 17449169 AFR_42425 Actinoplanes friuliensis DSM 7358 undecaprenyl-phosphate galactose phosphotransferase YP_008739792.1 9244497 D 1246995 CDS YP_008739793.1 556571368 17449170 9247098..9248309 1 NC_022657.1 COG3275 Putative regulator of cell autolysis; histidine kinase internal region 9248309 17449170 AFR_42430 Actinoplanes friuliensis DSM 7358 histidine kinase internal region YP_008739793.1 9247098 D 1246995 CDS YP_008739794.1 556571369 17449171 9248306..9249049 1 NC_022657.1 COG3279 Response regulator of the LytR/AlgR family; Chemotaxis response regulator protein-glutamate methylesterase 9249049 17449171 AFR_42435 Actinoplanes friuliensis DSM 7358 Chemotaxis response regulator protein-glutamate methylesterase YP_008739794.1 9248306 D 1246995 CDS YP_008739795.1 556571370 17449172 9249194..9249901 1 NC_022657.1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; putative two-component system response regulator 9249901 17449172 AFR_42440 Actinoplanes friuliensis DSM 7358 putative two-component system response regulator YP_008739795.1 9249194 D 1246995 CDS YP_008739796.1 556571371 17449173 9249898..9250962 1 NC_022657.1 COG0642 Signal transduction histidine kinase; putative two-component system sensor kinase 9250962 17449173 AFR_42445 Actinoplanes friuliensis DSM 7358 putative two-component system sensor kinase YP_008739796.1 9249898 D 1246995 CDS YP_008739797.1 556571372 17449174 9251123..9252724 1 NC_022657.1 hypothetical protein 9252724 17449174 AFR_42450 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739797.1 9251123 D 1246995 CDS YP_008739798.1 556571373 17449175 9252925..9253263 1 NC_022657.1 hypothetical protein 9253263 17449175 AFR_42455 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739798.1 9252925 D 1246995 CDS YP_008739799.1 556571374 17449176 9253260..9254897 1 NC_022657.1 COG4147 Predicted symporter; Sodium/glucose cotransporter 1 9254897 17449176 AFR_42460 Actinoplanes friuliensis DSM 7358 Sodium/glucose cotransporter 1 YP_008739799.1 9253260 D 1246995 CDS YP_008739800.1 556571375 17449177 9254992..9255630 1 NC_022657.1 COG0797 Lipoproteins; putative 23.9 kDa protein in glnII region 9255630 17449177 AFR_42465 Actinoplanes friuliensis DSM 7358 putative 23.9 kDa protein in glnII region YP_008739800.1 9254992 D 1246995 CDS YP_008739801.1 556571376 17449178 9255721..9256497 1 NC_022657.1 COG1131 ABC-type multidrug transport system, ATPase component; ABC transporter-like protein 9256497 17449178 AFR_42470 Actinoplanes friuliensis DSM 7358 ABC transporter-like protein YP_008739801.1 9255721 D 1246995 CDS YP_008739802.1 556571377 17449179 9256488..9258086 1 NC_022657.1 ABC transporter permease 9258086 17449179 AFR_42475 Actinoplanes friuliensis DSM 7358 ABC transporter permease YP_008739802.1 9256488 D 1246995 CDS YP_008739803.1 556571378 17449180 complement(9258080..9259105) 1 NC_022657.1 COG0180 Tryptophanyl-tRNA synthetase; tryptophanyl-tRNA synthetase 9259105 17449180 AFR_42480 Actinoplanes friuliensis DSM 7358 tryptophanyl-tRNA synthetase YP_008739803.1 9258080 R 1246995 CDS YP_008739804.1 556571379 17449181 9259272..9259802 1 NC_022657.1 COG1853 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family; putative flavin reductase 9259802 17449181 AFR_42485 Actinoplanes friuliensis DSM 7358 putative flavin reductase YP_008739804.1 9259272 D 1246995 CDS YP_008739805.1 556571380 17449182 9259913..9260329 1 NC_022657.1 COG3162 Predicted membrane protein; hypothetical protein 9260329 17449182 AFR_42490 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739805.1 9259913 D 1246995 CDS YP_008739806.1 556571381 17449183 9260329..9262008 1 NC_022657.1 COG4147 Predicted symporter; putative sodium:solute symporter 9262008 17449183 AFR_42495 Actinoplanes friuliensis DSM 7358 putative sodium:solute symporter YP_008739806.1 9260329 D 1246995 CDS YP_008739807.1 556571382 17449184 9262080..9263045 1 NC_022657.1 COG0451 Nucleoside-diphosphate-sugar epimerases; nad-dependent epimerase/dehydratase 9263045 17449184 AFR_42500 Actinoplanes friuliensis DSM 7358 nad-dependent epimerase/dehydratase YP_008739807.1 9262080 D 1246995 CDS YP_008739808.1 556571383 17449185 9263234..9264445 1 NC_022657.1 COG1316 Transcriptional regulator; putative cell envelope-related transcriptional attenuator 9264445 17449185 AFR_42505 Actinoplanes friuliensis DSM 7358 putative cell envelope-related transcriptional attenuator YP_008739808.1 9263234 D 1246995 CDS YP_008739809.1 556571384 17449186 9264607..9265788 1 NC_022657.1 COG1316 Transcriptional regulator; LytR/CpsA family cell envelope-related function transcriptional attenuator 9265788 17449186 AFR_42510 Actinoplanes friuliensis DSM 7358 LytR/CpsA family cell envelope-related function transcriptional attenuator YP_008739809.1 9264607 D 1246995 CDS YP_008739810.1 556571385 17449187 9265804..9266139 1 NC_022657.1 COG0607 Rhodanese-related sulfurtransferase; hypothetical protein 9266139 17449187 AFR_42515 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739810.1 9265804 D 1246995 CDS YP_008739811.1 556571386 17449188 9266136..9266924 1 NC_022657.1 COG0584 Glycerophosphoryl diester phosphodiesterase; putative glycerophosphoryl diester phosphodiesterase 9266924 17449188 AFR_42520 Actinoplanes friuliensis DSM 7358 putative glycerophosphoryl diester phosphodiesterase YP_008739811.1 9266136 D 1246995 CDS YP_008739812.1 556571387 17449189 9267010..9268464 1 NC_022657.1 COG0642 Signal transduction histidine kinase; pas/pac sensor signal transduction histidine kinase 9268464 17449189 AFR_42525 Actinoplanes friuliensis DSM 7358 pas/pac sensor signal transduction histidine kinase YP_008739812.1 9267010 D 1246995 CDS YP_008739813.1 556571388 17449190 9268538..9269422 1 NC_022657.1 hypothetical protein 9269422 17449190 AFR_42530 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739813.1 9268538 D 1246995 CDS YP_008739814.1 556571389 17449191 9269422..9270168 1 NC_022657.1 COG2273 Beta-glucanase/Beta-glucan synthetase; glycoside hydrolase family 16 9270168 17449191 AFR_42535 Actinoplanes friuliensis DSM 7358 glycoside hydrolase family 16 YP_008739814.1 9269422 D 1246995 CDS YP_008739815.1 556571390 17449192 complement(9270300..9271457) 1 NC_022657.1 COG2235 Arginine deiminase; arginine deiminase 9271457 17449192 AFR_42540 Actinoplanes friuliensis DSM 7358 arginine deiminase YP_008739815.1 9270300 R 1246995 CDS YP_008739816.1 556571391 17449193 9271774..9272532 1 NC_022657.1 hypothetical protein 9272532 17449193 AFR_42545 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739816.1 9271774 D 1246995 CDS YP_008739817.1 556571392 17449194 9272680..9273156 1 NC_022657.1 hypothetical protein 9273156 17449194 AFR_42550 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739817.1 9272680 D 1246995 CDS YP_008739818.1 556571393 17449195 9273268..9273621 1 NC_022657.1 COG3603 Uncharacterized conserved protein; hypothetical protein 9273621 17449195 AFR_42555 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739818.1 9273268 D 1246995 CDS YP_008739819.1 556571394 17449196 9273696..9274292 1 NC_022657.1 putative global transcription activator SNF2L2 9274292 17449196 AFR_42560 Actinoplanes friuliensis DSM 7358 putative global transcription activator SNF2L2 YP_008739819.1 9273696 D 1246995 CDS YP_008739820.1 556571395 17449197 9274320..9275276 1 NC_022657.1 COG0077 Prephenate dehydratase; putative prephenate dehydratase 9275276 17449197 AFR_42565 Actinoplanes friuliensis DSM 7358 putative prephenate dehydratase YP_008739820.1 9274320 D 1246995 CDS YP_008739821.1 556571396 17449198 complement(9275332..9276066) 1 NC_022657.1 COG2013 Uncharacterized conserved protein; hypothetical protein 9276066 17449198 AFR_42570 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739821.1 9275332 R 1246995 CDS YP_008739822.1 556571397 17449199 complement(9276132..9276485) 1 NC_022657.1 COG3824 Uncharacterized protein conserved in bacteria; hypothetical protein 9276485 17449199 AFR_42575 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739822.1 9276132 R 1246995 CDS YP_008739823.1 556571398 17449200 complement(9276538..9276966) 1 NC_022657.1 COG1764 Predicted redox protein, regulator of disulfide bond formation; osmotically inducible protein OsmC 9276966 17449200 AFR_42580 Actinoplanes friuliensis DSM 7358 osmotically inducible protein OsmC YP_008739823.1 9276538 R 1246995 CDS YP_008739824.1 556571399 17449201 9277034..9277795 1 NC_022657.1 hypothetical protein 9277795 17449201 AFR_42585 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739824.1 9277034 D 1246995 CDS YP_008739825.1 556571400 17449202 9277829..9279091 1 NC_022657.1 COG0172 Seryl-tRNA synthetase; seryl-tRNA ligase 9279091 17449202 AFR_42590 Actinoplanes friuliensis DSM 7358 seryl-tRNA ligase YP_008739825.1 9277829 D 1246995 CDS YP_008739826.1 556571401 17449203 9279200..9280012 1 NC_022657.1 COG0561 Predicted hydrolases of the HAD superfamily; HMP-PP phosphatase 9280012 17449203 AFR_42595 Actinoplanes friuliensis DSM 7358 HMP-PP phosphatase YP_008739826.1 9279200 D 1246995 CDS YP_008739827.1 556571402 17449204 9280012..9280818 1 NC_022657.1 COG0561 Predicted hydrolases of the HAD superfamily; putative haloacid dehalogenase-like hydrolase 9280818 17449204 AFR_42600 Actinoplanes friuliensis DSM 7358 putative haloacid dehalogenase-like hydrolase YP_008739827.1 9280012 D 1246995 CDS YP_008739828.1 556571403 17449205 complement(9280815..9281390) 1 NC_022657.1 hypothetical protein 9281390 17449205 AFR_42605 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739828.1 9280815 R 1246995 CDS YP_008739829.1 556571404 17449206 complement(9281426..9282211) 1 NC_022657.1 COG1834 N-Dimethylarginine dimethylaminohydrolase; hypothetical protein 9282211 17449206 AFR_42610 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739829.1 9281426 R 1246995 CDS YP_008739830.1 556571405 17449207 9282321..9282779 1 NC_022657.1 COG1522 Transcriptional regulators; putative AsnC-family transcriptional regulator 9282779 17449207 AFR_42615 Actinoplanes friuliensis DSM 7358 putative AsnC-family transcriptional regulator YP_008739830.1 9282321 D 1246995 CDS YP_008739831.1 556571406 17449208 9282818..9284713 1 NC_022657.1 COG4880 Secreted protein containing C-terminal beta-propeller domain distantly related to WD-40 repeats; hypothetical protein 9284713 17449208 AFR_42620 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739831.1 9282818 D 1246995 CDS YP_008739832.1 556571407 17449209 complement(9284710..9285807) 1 NC_022657.1 hypothetical protein 9285807 17449209 AFR_42625 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739832.1 9284710 R 1246995 CDS YP_008739833.1 556571408 17449210 complement(9285857..9286099) 1 NC_022657.1 hypothetical protein 9286099 17449210 AFR_42630 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739833.1 9285857 R 1246995 CDS YP_008739834.1 556571409 17449211 complement(9286096..9286677) 1 NC_022657.1 hypothetical protein 9286677 17449211 AFR_42635 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739834.1 9286096 R 1246995 CDS YP_008739835.1 556571410 17449212 9286834..9287634 1 NC_022657.1 COG1526 Uncharacterized protein required for formate dehydrogenase activity; Protein fdhD 9287634 17449212 AFR_42640 Actinoplanes friuliensis DSM 7358 Protein fdhD YP_008739835.1 9286834 D 1246995 CDS YP_008739836.1 556571411 17449213 9287738..9289387 1 NC_022657.1 COG3540 Phosphodiesterase/alkaline phosphatase D; alkaline phosphatase 9289387 17449213 AFR_42645 Actinoplanes friuliensis DSM 7358 alkaline phosphatase YP_008739836.1 9287738 D 1246995 CDS YP_008739837.1 556571412 17449214 complement(9289400..9290875) 1 NC_022657.1 hypothetical protein 9290875 17449214 AFR_42650 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739837.1 9289400 R 1246995 CDS YP_008739838.1 556571413 17449215 complement(9290931..9291434) 1 NC_022657.1 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; putative acetyltransferase 9291434 17449215 AFR_42655 Actinoplanes friuliensis DSM 7358 putative acetyltransferase YP_008739838.1 9290931 R 1246995 CDS YP_008739839.1 556571414 17449216 9291491..9292372 1 NC_022657.1 COG3001 Fructosamine-3-kinase; aminoglycoside phosphotransferase 9292372 17449216 AFR_42660 Actinoplanes friuliensis DSM 7358 aminoglycoside phosphotransferase YP_008739839.1 9291491 D 1246995 CDS YP_008739840.1 556571415 17449217 9292509..9293510 1 NC_022657.1 COG2896 Molybdenum cofactor biosynthesis enzyme; molybdenum cofactor biosynthesis protein A 9293510 moaA 17449217 moaA Actinoplanes friuliensis DSM 7358 molybdenum cofactor biosynthesis protein A YP_008739840.1 9292509 D 1246995 CDS YP_008739841.1 556571416 17449218 9293572..9293820 1 NC_022657.1 putative molybdopterin converting factor 9293820 17449218 AFR_42670 Actinoplanes friuliensis DSM 7358 putative molybdopterin converting factor YP_008739841.1 9293572 D 1246995 CDS YP_008739842.1 556571417 17449219 9293826..9295589 1 NC_022657.1 COG1408 Predicted phosphohydrolases; putative metallophosphoesterase 9295589 17449219 AFR_42675 Actinoplanes friuliensis DSM 7358 putative metallophosphoesterase YP_008739842.1 9293826 D 1246995 CDS YP_008739843.1 556571418 17449220 9295714..9298875 1 NC_022657.1 COG1379 Uncharacterized conserved protein; putative UvrD/REP helicase 9298875 17449220 AFR_42680 Actinoplanes friuliensis DSM 7358 putative UvrD/REP helicase YP_008739843.1 9295714 D 1246995 CDS YP_008739844.1 556571419 17449221 complement(9299028..9299372) 1 NC_022657.1 hypothetical protein 9299372 17449221 AFR_42685 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739844.1 9299028 R 1246995 CDS YP_008739845.1 556571420 17449222 complement(9299473..9299988) 1 NC_022657.1 hypothetical protein 9299988 17449222 AFR_42690 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739845.1 9299473 R 1246995 CDS YP_008739846.1 556571421 17449223 9300348..9301049 1 NC_022657.1 hypothetical protein 9301049 17449223 AFR_42695 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739846.1 9300348 D 1246995 CDS YP_008739847.1 556571422 17449224 9301140..9302342 1 NC_022657.1 COG3899 Predicted ATPase; hypothetical protein 9302342 17449224 AFR_42700 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739847.1 9301140 D 1246995 CDS YP_008739848.1 556571423 17449225 complement(9302339..9302821) 1 NC_022657.1 COG3153 Predicted acetyltransferase; GCN5-like N-acetyltransferase 9302821 17449225 AFR_42705 Actinoplanes friuliensis DSM 7358 GCN5-like N-acetyltransferase YP_008739848.1 9302339 R 1246995 CDS YP_008739849.1 556571424 17449226 9303071..9303583 1 NC_022657.1 DoxX family protein 9303583 17449226 AFR_42710 Actinoplanes friuliensis DSM 7358 DoxX family protein YP_008739849.1 9303071 D 1246995 CDS YP_008739850.1 556571425 17449227 9303666..9305183 1 NC_022657.1 hypothetical protein 9305183 17449227 AFR_42715 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739850.1 9303666 D 1246995 CDS YP_008739851.1 556571426 17449228 complement(9305251..9305682) 1 NC_022657.1 COG0314 Molybdopterin converting factor, large subunit; putative molybdopterin biosynthesis protein E 9305682 17449228 AFR_42720 Actinoplanes friuliensis DSM 7358 putative molybdopterin biosynthesis protein E YP_008739851.1 9305251 R 1246995 CDS YP_008739852.1 556571427 17449229 complement(9305679..9306905) 1 NC_022657.1 COG0303 Molybdopterin biosynthesis enzyme; putative molybdopterin biosynthesis protein A 9306905 17449229 AFR_42725 Actinoplanes friuliensis DSM 7358 putative molybdopterin biosynthesis protein A YP_008739852.1 9305679 R 1246995 CDS YP_008739853.1 556571428 17449230 complement(9306902..9307387) 1 NC_022657.1 COG0521 Molybdopterin biosynthesis enzymes; Putative competence-damage inducible protein 9307387 17449230 AFR_42730 Actinoplanes friuliensis DSM 7358 Putative competence-damage inducible protein YP_008739853.1 9306902 R 1246995 CDS YP_008739854.1 556571429 17449231 complement(9307384..9307857) 1 NC_022657.1 COG0315 Molybdenum cofactor biosynthesis enzyme; molybdenum cofactor biosynthesis protein C 9307857 17449231 AFR_42735 Actinoplanes friuliensis DSM 7358 molybdenum cofactor biosynthesis protein C YP_008739854.1 9307384 R 1246995 CDS YP_008739855.1 556571430 17449232 9308458..9310974 1 NC_022657.1 COG2199 FOG: GGDEF domain; diguanylate cyclase/phosphodiesterase 9310974 17449232 AFR_42740 Actinoplanes friuliensis DSM 7358 diguanylate cyclase/phosphodiesterase YP_008739855.1 9308458 D 1246995 CDS YP_008739856.1 556571431 17449233 9310971..9312206 1 NC_022657.1 hypothetical protein 9312206 17449233 AFR_42745 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739856.1 9310971 D 1246995 CDS YP_008739857.1 556571432 17449234 9312241..9312618 1 NC_022657.1 COG3809 Uncharacterized protein conserved in bacteria; hypothetical protein 9312618 17449234 AFR_42750 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739857.1 9312241 D 1246995 CDS YP_008739858.1 556571433 17449235 9312658..9313332 1 NC_022657.1 hypothetical protein 9313332 17449235 AFR_42755 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739858.1 9312658 D 1246995 CDS YP_008739859.1 556571434 17449236 complement(9313341..9314573) 1 NC_022657.1 hypothetical protein 9314573 17449236 AFR_42760 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739859.1 9313341 R 1246995 CDS YP_008739860.1 556571435 17449237 9314697..9315110 1 NC_022657.1 hypothetical protein 9315110 17449237 AFR_42765 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739860.1 9314697 D 1246995 CDS YP_008739861.1 556571436 17449238 9315088..9315438 1 NC_022657.1 hypothetical protein 9315438 17449238 AFR_42770 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739861.1 9315088 D 1246995 CDS YP_008739862.1 556571437 17449239 complement(9315698..9316018) 1 NC_022657.1 hypothetical protein 9316018 17449239 AFR_42775 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739862.1 9315698 R 1246995 CDS YP_008739863.1 556571438 17449240 complement(9320580..9320984) 1 NC_022657.1 hypothetical protein 9320984 17449240 AFR_42780 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739863.1 9320580 R 1246995 CDS YP_008739864.1 556571439 17449241 9322528..9322875 1 NC_022657.1 hypothetical protein 9322875 17449241 AFR_42785 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739864.1 9322528 D 1246995 CDS YP_008739865.1 556571440 17449242 9323008..9323343 1 NC_022657.1 hypothetical protein 9323343 17449242 AFR_42790 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739865.1 9323008 D 1246995 CDS YP_008739866.1 556571441 17449243 9323547..9324356 1 NC_022657.1 COG2357 Uncharacterized protein conserved in bacteria; hypothetical protein 9324356 17449243 AFR_42795 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739866.1 9323547 D 1246995 CDS YP_008739867.1 556571442 17449244 9324340..9325080 1 NC_022657.1 hypothetical protein 9325080 17449244 AFR_42800 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739867.1 9324340 D 1246995 CDS YP_008739868.1 556571443 17449245 complement(9325077..9326519) 1 NC_022657.1 COG0305 Replicative DNA helicase; replicative DNA helicase 9326519 17449245 AFR_42805 Actinoplanes friuliensis DSM 7358 replicative DNA helicase YP_008739868.1 9325077 R 1246995 CDS YP_008739869.1 556571444 17449246 9327094..9331188 1 NC_022657.1 Polycystic kidney disease protein 1-like 3 9331188 17449246 AFR_42810 Actinoplanes friuliensis DSM 7358 Polycystic kidney disease protein 1-like 3 YP_008739869.1 9327094 D 1246995 CDS YP_008739870.1 556571445 17449247 complement(9331270..9331719) 1 NC_022657.1 COG0359 Ribosomal protein L9; 50S ribosomal protein L9 9331719 rplI 17449247 rplI Actinoplanes friuliensis DSM 7358 50S ribosomal protein L9 YP_008739870.1 9331270 R 1246995 CDS YP_008739871.1 556571446 17449248 complement(9331734..9331973) 1 NC_022657.1 COG0238 Ribosomal protein S18; 30S ribosomal protein S18 9331973 rpsR 17449248 rpsR Actinoplanes friuliensis DSM 7358 30S ribosomal protein S18 YP_008739871.1 9331734 R 1246995 CDS YP_008739872.1 556571447 17449249 complement(9332012..9332578) 1 NC_022657.1 COG0629 Single-stranded DNA-binding protein; putative single-stranded DNA-binding protein 9332578 17449249 AFR_42825 Actinoplanes friuliensis DSM 7358 putative single-stranded DNA-binding protein YP_008739872.1 9332012 R 1246995 CDS YP_008739873.1 556571448 17449250 complement(9332648..9332938) 1 NC_022657.1 COG0360 Ribosomal protein S6; 30S ribosomal protein S6 9332938 17449250 AFR_42830 Actinoplanes friuliensis DSM 7358 30S ribosomal protein S6 YP_008739873.1 9332648 R 1246995 CDS YP_008739874.1 556571449 17449251 complement(9333229..9334200) 1 NC_022657.1 Myosin light chain kinase 2, skeletal/cardiac muscle 9334200 17449251 AFR_42835 Actinoplanes friuliensis DSM 7358 Myosin light chain kinase 2, skeletal/cardiac muscle YP_008739874.1 9333229 R 1246995 CDS YP_008739875.1 556571450 17449252 9334374..9335150 1 NC_022657.1 COG0648 Endonuclease IV; endonuclease IV 9335150 17449252 AFR_42840 Actinoplanes friuliensis DSM 7358 endonuclease IV YP_008739875.1 9334374 D 1246995 CDS YP_008739876.1 556571451 17449253 complement(9335999..9336250) 1 NC_022657.1 hypothetical protein 9336250 17449253 AFR_42845 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739876.1 9335999 R 1246995 CDS YP_008739877.1 556571452 17449254 9336414..9338213 1 NC_022657.1 hypothetical protein 9338213 17449254 AFR_42850 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739877.1 9336414 D 1246995 CDS YP_008739878.1 556571453 17449255 complement(9338333..9339877) 1 NC_022657.1 COG5650 Predicted integral membrane protein; hypothetical protein 9339877 17449255 AFR_42855 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739878.1 9338333 R 1246995 CDS YP_008739879.1 556571454 17449256 complement(9340008..9342698) 1 NC_022657.1 COG0744 Membrane carboxypeptidase (penicillin-binding protein); putative transglycosylase 9342698 17449256 AFR_42860 Actinoplanes friuliensis DSM 7358 putative transglycosylase YP_008739879.1 9340008 R 1246995 CDS YP_008739880.1 556571455 17449257 complement(9343050..9343517) 1 NC_022657.1 hypothetical protein 9343517 17449257 AFR_42865 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739880.1 9343050 R 1246995 CDS YP_008739881.1 556571456 17449258 9343673..9344278 1 NC_022657.1 COG1695 Predicted transcriptional regulators; Negative transcription regulator padR 9344278 17449258 AFR_42870 Actinoplanes friuliensis DSM 7358 Negative transcription regulator padR YP_008739881.1 9343673 D 1246995 CDS YP_008739882.1 556571457 17449259 9344299..9345378 1 NC_022657.1 COG1260 Myo-inositol-1-phosphate synthase; putative 1L-myo-inositol-1-phosphate synthase 9345378 17449259 AFR_42875 Actinoplanes friuliensis DSM 7358 putative 1L-myo-inositol-1-phosphate synthase YP_008739882.1 9344299 D 1246995 CDS YP_008739883.1 556571458 17449260 9345596..9346024 1 NC_022657.1 hypothetical protein 9346024 17449260 AFR_42880 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739883.1 9345596 D 1246995 CDS YP_008739884.1 556571459 17449261 complement(9346021..9346479) 1 NC_022657.1 COG0350 Methylated DNA-protein cysteine methyltransferase; methylated-DNA-[protein]-cysteine S-methyltransferase 9346479 17449261 AFR_42885 Actinoplanes friuliensis DSM 7358 methylated-DNA-[protein]-cysteine S-methyltransferase YP_008739884.1 9346021 R 1246995 CDS YP_008739885.1 556571460 17449262 9346580..9347101 1 NC_022657.1 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; putative RNA polymerase ECF-subfamily sigma factor 9347101 17449262 AFR_42890 Actinoplanes friuliensis DSM 7358 putative RNA polymerase ECF-subfamily sigma factor YP_008739885.1 9346580 D 1246995 CDS YP_008739886.1 556571461 17449263 9347110..9348186 1 NC_022657.1 COG0823 Periplasmic component of the Tol biopolymer transport system; putative WD repeat-containing protein 9348186 17449263 AFR_42895 Actinoplanes friuliensis DSM 7358 putative WD repeat-containing protein YP_008739886.1 9347110 D 1246995 CDS YP_008739887.1 556571462 17449264 complement(9348239..9349669) 1 NC_022657.1 COG0617 tRNA nucleotidyltransferase/poly(A) polymerase; polynucleotide adenylyltransferase/metal dependent phosphohydrolase 9349669 17449264 AFR_42900 Actinoplanes friuliensis DSM 7358 polynucleotide adenylyltransferase/metal dependent phosphohydrolase YP_008739887.1 9348239 R 1246995 CDS YP_008739888.1 556571463 17449265 9349764..9350663 1 NC_022657.1 hypothetical protein 9350663 17449265 AFR_42905 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739888.1 9349764 D 1246995 CDS YP_008739889.1 556571464 17449266 9350715..9352484 1 NC_022657.1 COG0728 Uncharacterized membrane protein, putative virulence factor; putative transmembrane protein 9352484 17449266 AFR_42910 Actinoplanes friuliensis DSM 7358 putative transmembrane protein YP_008739889.1 9350715 D 1246995 CDS YP_008739890.1 556571465 17449267 9352663..9354207 1 NC_022657.1 COG0515 Serine/threonine protein kinase; hypothetical protein 9354207 17449267 AFR_42915 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739890.1 9352663 D 1246995 CDS YP_008739891.1 556571466 17449268 9354254..9354985 1 NC_022657.1 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; ECF subfamily RNA polymerase sigma-24 subunit 9354985 17449268 AFR_42920 Actinoplanes friuliensis DSM 7358 ECF subfamily RNA polymerase sigma-24 subunit YP_008739891.1 9354254 D 1246995 CDS YP_008739892.1 556571467 17449269 9354982..9355953 1 NC_022657.1 hypothetical protein 9355953 17449269 AFR_42925 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739892.1 9354982 D 1246995 CDS YP_008739893.1 556571468 17449270 9356098..9357057 1 NC_022657.1 COG0492 Thioredoxin reductase; putative thioredoxin reductase 9357057 17449270 AFR_42930 Actinoplanes friuliensis DSM 7358 putative thioredoxin reductase YP_008739893.1 9356098 D 1246995 CDS YP_008739894.1 556571469 17449271 9357074..9357397 1 NC_022657.1 COG0526 Thiol-disulfide isomerase and thioredoxins; thioredoxin 9357397 17449271 AFR_42935 Actinoplanes friuliensis DSM 7358 thioredoxin YP_008739894.1 9357074 D 1246995 CDS YP_008739895.1 556571470 17449272 9357582..9358733 1 NC_022657.1 COG3409 Putative peptidoglycan-binding domain-containing protein; putative N-acetylmuramoyl-L-alanine amidase 9358733 17449272 AFR_42940 Actinoplanes friuliensis DSM 7358 putative N-acetylmuramoyl-L-alanine amidase YP_008739895.1 9357582 D 1246995 CDS YP_008739896.1 556571471 17449273 complement(9358872..9359537) 1 NC_022657.1 hypothetical protein 9359537 17449273 AFR_42945 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739896.1 9358872 R 1246995 CDS YP_008739897.1 556571472 17449274 9359738..9361030 1 NC_022657.1 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs; GntR family transcriptional regulator 9361030 17449274 AFR_42950 Actinoplanes friuliensis DSM 7358 GntR family transcriptional regulator YP_008739897.1 9359738 D 1246995 CDS YP_008739898.1 556571473 17449275 9361039..9362001 1 NC_022657.1 COG1181 D-alanine-D-alanine ligase and related ATP-grasp enzymes; D-alanine--D-alanine ligase 9362001 17449275 AFR_42955 Actinoplanes friuliensis DSM 7358 D-alanine--D-alanine ligase YP_008739898.1 9361039 D 1246995 CDS YP_008739899.1 556571474 17449276 complement(9362910..9364010) 1 NC_022657.1 hypothetical protein 9364010 17449276 AFR_42960 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739899.1 9362910 R 1246995 CDS YP_008739900.1 556571475 17449277 complement(9368615..9369682) 1 NC_022657.1 COG1475 Predicted transcriptional regulators; putative parB-like partition protein 9369682 17449277 AFR_42965 Actinoplanes friuliensis DSM 7358 putative parB-like partition protein YP_008739900.1 9368615 R 1246995 CDS YP_008739901.1 556571476 17449278 complement(9369679..9370530) 1 NC_022657.1 COG1192 ATPases involved in chromosome partitioning; formate-tetrahydrofolate ligase 9370530 17449278 AFR_42970 Actinoplanes friuliensis DSM 7358 formate-tetrahydrofolate ligase YP_008739901.1 9369679 R 1246995 CDS YP_008739902.1 556571477 17449279 complement(9371572..9372282) 1 NC_022657.1 COG0357 Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division; 16S rRNA methyltransferase GidB 9372282 gidB 17449279 gidB Actinoplanes friuliensis DSM 7358 16S rRNA methyltransferase GidB YP_008739902.1 9371572 R 1246995 CDS YP_008739903.1 556571478 17449280 complement(9372868..9373443) 1 NC_022657.1 COG1847 Predicted RNA-binding protein; Protein jag 9373443 17449280 AFR_42980 Actinoplanes friuliensis DSM 7358 Protein jag YP_008739903.1 9372868 R 1246995 CDS YP_008739904.1 556571479 17449281 complement(9373596..9374636) 1 NC_022657.1 COG0706 Preprotein translocase subunit YidC; preprotein translocase subunit YidC 9374636 17449281 AFR_42985 Actinoplanes friuliensis DSM 7358 preprotein translocase subunit YidC YP_008739904.1 9373596 R 1246995 CDS YP_008739905.1 556571480 17449282 complement(9374638..9374877) 1 NC_022657.1 COG0759 Uncharacterized conserved protein; hypothetical protein 9374877 17449282 AFR_42990 Actinoplanes friuliensis DSM 7358 hypothetical protein YP_008739905.1 9374638 R 1246995 CDS YP_008739906.1 556571481 17449283 complement(9374913..9375143) 1 NC_022657.1 Ribonuclease P protein component 9375143 17449283 AFR_42995 Actinoplanes friuliensis DSM 7358 Ribonuclease P protein component YP_008739906.1 9374913 R 1246995 CDS YP_008739907.1 556571482 17449284 complement(9375304..9375441) 1 NC_022657.1 COG0230 Ribosomal protein L34; putative ribosomal protein L34 9375441 17449284 AFR_43000 Actinoplanes friuliensis DSM 7358 putative ribosomal protein L34 YP_008739907.1 9375304 R 1246995 CDS