-- dump date 20140618_184754 -- class Genbank::CDS -- table cds_note -- id note YP_001219877.1 TIGRFAM: heavy metal response regulator; PFAM: response regulator receiver; transcriptional regulator domain protein YP_001219878.1 TIGRFAM: heavy metal sensor kinase; PFAM: ATP-binding region, ATPase domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein YP_001219879.1 PFAM: outer membrane efflux protein YP_001219881.1 PFAM: acriflavin resistance protein YP_001219882.1 PFAM: transposase IS116/IS110/IS902 family protein YP_001219887.1 PFAM: transposase, IS111A/IS1328/IS1533; transposase IS116/IS110/IS902 family protein YP_001219888.1 PFAM: transposase IS116/IS110/IS902 family protein YP_001219892.1 PFAM: Na+/H+ antiporter NhaA YP_001219894.1 PFAM: transposase, IS4 family protein YP_001219895.1 PFAM: transposase, mutator type YP_001219897.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase YP_001219899.1 PFAM: DoxX family protein YP_001219901.1 Enables the enzymatic reduction of mercuric ions to elemental mercury YP_001219903.1 PFAM: glycoside hydrolase, family 39 YP_001219904.1 PFAM: glucose-methanol-choline oxidoreductase; FAD dependent oxidoreductase; GMC oxidoreductase YP_001219905.1 PFAM: short-chain dehydrogenase/reductase SDR; KR YP_001219908.1 PFAM: putative carbohydrate binding; glycosyltransferase 36; glycosyltransferase 36 associated YP_001219909.1 PFAM: transposase, IS4 family protein YP_001219911.1 PFAM: Cyclopropane-fatty-acyl-phospholipid synthase; Methyltransferase type 11; Methyltransferase type 12 YP_001219912.1 PFAM: protein of unknown function UPF0118 YP_001219913.1 TIGRFAM: esterase, PHB depolymerase family YP_001219914.1 PFAM: CsbD family protein YP_001219915.1 PFAM: helix-turn-helix domain protein YP_001219922.1 PFAM: transposase, IS111A/IS1328/IS1533; transposase IS116/IS110/IS902 family protein YP_001219923.1 PFAM: transposase, IS111A/IS1328/IS1533; transposase IS116/IS110/IS902 family protein YP_001219924.1 FOG: Transposase-like protein YP_001219926.1 PFAM: Na+/H+ antiporter NhaA YP_001219927.1 PFAM: transposase, IS4 family protein YP_001219928.1 PFAM: Na+/H+ antiporter NhaA YP_001219930.1 PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase YP_001219931.1 PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase YP_001219932.1 PFAM: Integrase, catalytic region YP_001219934.1 PFAM: CheB methylesterase; MCP methyltransferase, CheR-type; regulatory protein, LuxR; response regulator receiver; ATP-binding region, ATPase domain protein; histidine kinase A domain protein; Sigma-70, region 4 type 2; PAS fold-4 domain protein YP_001219935.1 PFAM: transposase, IS111A/IS1328/IS1533; transposase IS116/IS110/IS902 family protein YP_001219936.1 PFAM: regulatory protein GntR, HTH YP_001219937.1 PFAM: transposase, mutator type YP_001219939.1 PFAM: plasmid stabilization system YP_001219943.1 PFAM: WGR domain protein YP_001219945.1 PFAM: PilT protein domain protein YP_001219949.1 PFAM: transposase, mutator type YP_001219957.1 PFAM: helix-turn-helix domain protein YP_001219958.1 PFAM: CsbD family protein YP_001219959.1 TIGRFAM: esterase, PHB depolymerase family YP_001219960.1 PFAM: protein of unknown function UPF0118 YP_001219964.1 PFAM: band 7 protein YP_001219965.1 FOG: Transposase-like protein YP_001219966.1 PFAM: transposase, IS4 family protein YP_001219970.1 TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; plasma-membrane proton-efflux P-type ATPase; PFAM: cation transporting ATPase domain protein; Haloacid dehalogenase domain protein hydrolase; E1-E2 ATPase-associated domain protein YP_001219971.1 PFAM: transposase, IS111A/IS1328/IS1533; transposase IS116/IS110/IS902 family protein YP_001219972.1 PFAM: transposase, IS4 family protein YP_001219975.1 PFAM: transposase, mutator type YP_001219976.1 PFAM: transposase, IS4 family protein YP_001219977.1 PFAM: cyclic nucleotide-binding; regulatory protein, Crp YP_001219978.1 PFAM: Na+/H+ antiporter NhaA YP_001219979.1 PFAM: UbiE/COQ5 methyltransferase; Methyltransferase type 11; Methyltransferase type 12 YP_001219982.1 PFAM: transposase, mutator type YP_001219983.1 PFAM: Integrase, catalytic region YP_001219984.1 PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase YP_001219985.1 PFAM: transposase, IS4 family protein YP_001219988.1 PFAM: aldehyde dehydrogenase YP_001219995.1 TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: Haloacid dehalogenase domain protein hydrolase YP_001219996.1 PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase YP_001219997.1 PFAM: Integrase, catalytic region YP_001219998.1 PFAM: Heavy metal transport/detoxification protein; E1-E2 ATPase-associated domain protein YP_001219999.1 PFAM: regulatory protein, MerR YP_001220000.1 PFAM: major facilitator superfamily MFS_1 YP_001220001.1 PFAM: beta-lactamase domain protein YP_001220002.1 PFAM: Rhodanese domain protein; regulatory protein, ArsR YP_001220003.1 TIGRFAM: addiction module antidote protein, HigA family YP_001220004.1 PFAM: plasmid maintenance system killer YP_001220005.1 PFAM: phage integrase domain protein SAM domain protein YP_001220006.1 PFAM: transposase, mutator type YP_001220009.1 PFAM: plasmid stabilization system YP_001220010.1 PFAM: Heme NO binding domain protein YP_001220011.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein YP_001220012.1 PFAM: transposase, IS204/IS1001/IS1096/IS1165 family protein YP_001220013.1 PFAM: helix-turn-helix, Fis-type; Resolvase helix-turn-helix domain protein YP_001220014.1 PFAM: Rhodanese domain protein; regulatory protein, ArsR YP_001220015.1 PFAM: beta-lactamase domain protein YP_001220016.1 PFAM: major facilitator superfamily MFS_1 YP_001220021.1 PFAM: phage integrase family protein YP_001220022.1 PFAM: phage integrase family protein YP_001220023.1 PFAM: phage integrase family protein; phage integrase domain protein SAM domain protein YP_001220024.1 PFAM: domain of unknown function DUF1738 YP_001220025.1 PFAM: PilT protein domain protein YP_001220026.1 PFAM: Rv0623 family protein transcription factor YP_001220027.1 PFAM: GCN5-related N-acetyltransferase YP_001220029.1 PFAM: WGR domain protein YP_001220030.1 TIGRFAM: helicase, RecD/TraA family; SMART: Helix-hairpin-helix DNA-binding, class 1; AAA ATPase YP_001220031.1 PFAM: replication protein C YP_001220032.1 TIGRFAM: parB-like partition protein; PFAM: ParB domain protein nuclease; RepB plasmid partition YP_001220033.1 PFAM: regulatory protein, MerR; Cobyrinic acid a,c-diamide synthase YP_001220034.1 PFAM: phage integrase family protein; phage integrase domain protein SAM domain protein YP_001220036.1 TIGRFAM: DNA binding domain, excisionase family YP_001220041.1 PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; BFD domain protein [2Fe-2S]-binding domain protein YP_001220042.1 TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase YP_001220047.1 TIGRFAM: DNA polymerase III, alpha subunit; PFAM: PHP C-terminal domain protein; nucleic acid binding, OB-fold, tRNA/helicase-type; SMART: phosphoesterase PHP domain protein YP_001220049.1 PFAM: UvrD/REP helicase YP_001220050.1 PFAM: protein of unknown function DUF159 YP_001220051.1 PFAM: putative transposase, IS891/IS1136/IS1341 family YP_001220052.1 PFAM: Integrase, catalytic region YP_001220053.1 PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase YP_001220055.1 PFAM: transposase IS200-family protein YP_001220057.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein YP_001220058.1 PFAM: protein of unknown function DUF214 YP_001220059.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001220061.1 PFAM: replication protein C YP_001220062.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001220063.1 PFAM: protein of unknown function DUF1228; major facilitator superfamily MFS_1 YP_001220064.1 PFAM: 2-nitropropane dioxygenase, NPD YP_001220068.1 TIGRFAM: CRISPR-associated helicase Cas3; PFAM: helicase domain protein YP_001220069.1 TIGRFAM: CRISPR-associated protein, Cse1 family YP_001220071.1 TIGRFAM: CRISPR-associated protein, Cse4 family YP_001220072.1 TIGRFAM: CRISPR-associated protein Cas5 family; CRISPR-associated protein Cas5 YP_001220073.1 TIGRFAM: CRISPR-associated protein, Cse3 family; PFAM: CRISPR-associated protein, CT1974 YP_001220074.1 TIGRFAM: CRISPR-associated protein Cas1 YP_001220078.1 PFAM: regulatory protein, MerR; Resolvase, N-terminal domain YP_001220079.1 TIGRFAM: transposase, IS605 OrfB family; PFAM: putative transposase, IS891/IS1136/IS1341 family; transposase, IS605 OrfB YP_001220080.1 PFAM: DNA recombination protein RuvA, domain I; SMART: Helix-hairpin-helix DNA-binding, class 1 YP_001220081.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration YP_001220085.1 PFAM: YceI family protein YP_001220086.1 PFAM: cytochrome B561 YP_001220088.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein YP_001220091.1 PFAM: protein of unknown function DUF6, transmembrane YP_001220092.1 PFAM: Resolvase, N-terminal domain; Resolvase helix-turn-helix domain protein YP_001220093.1 PFAM: transposase IS3/IS911 family protein YP_001220096.1 PFAM: metallophosphoesterase YP_001220097.1 PFAM: metallophosphoesterase YP_001220099.1 PFAM: regulatory protein, IclR YP_001220100.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001220101.1 catalyzes the formation of L-ornithine from N(2)-acetyl-L-ornithine YP_001220102.1 PFAM: NUDIX hydrolase YP_001220103.1 PFAM: Na+/solute symporter YP_001220105.1 PFAM: restriction endonuclease YP_001220106.1 PFAM: helix-turn-helix domain protein YP_001220111.1 PFAM: filamentation induced by cAMP protein Fic YP_001220116.1 PFAM: nucleoside 2-deoxyribosyltransferase YP_001220117.1 PFAM: Radical SAM domain protein YP_001220118.1 PFAM: Radical SAM domain protein YP_001220119.1 PFAM: AAA ATPase, central domain protein; ATPase associated with various cellular activities, AAA_5 YP_001220122.1 PFAM: sigma-70 region 4 domain protein YP_001220124.1 PFAM: helix-turn-helix domain protein YP_001220125.1 PFAM: HipA domain protein YP_001220126.1 PFAM: IstB domain protein ATP-binding protein YP_001220128.1 PFAM: D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase YP_001220131.1 PFAM: transposase, IS4 family protein YP_001220134.1 PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; thiamine pyrophosphate enzyme, central region; thiamine pyrophosphate enzyme TPP binding domain protein YP_001220135.1 PFAM: ferredoxin-dependent glutamate synthase YP_001220136.1 PFAM: MltA-interacting MipA family protein YP_001220138.1 PFAM: transposase, mutator type YP_001220141.1 PFAM: Resolvase, N-terminal domain; Recombinase YP_001220142.1 PFAM: Integrase, catalytic region YP_001220143.1 PFAM: transposase, IS111A/IS1328/IS1533; transposase IS116/IS110/IS902 family protein YP_001220144.1 PFAM: transposase IS3/IS911 family protein YP_001220145.1 PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; Male sterility C-terminal domain YP_001220146.1 PFAM: regulatory protein, MerR YP_001220148.1 PFAM: Integrase, catalytic region YP_001220149.1 PFAM: IstB domain protein ATP-binding protein; IstB ATP binding N-terminal domain protein; SMART: AAA ATPase YP_001220151.1 PFAM: helix-turn-helix- domain containing protein, AraC type; AraC protein, arabinose-binding/dimerisation YP_001220152.1 PFAM: regulatory protein GntR, HTH; GntR domain protein YP_001220153.1 PFAM: Carboxymuconolactone decarboxylase YP_001220154.1 PFAM: NADP oxidoreductase, coenzyme F420-dependent; 6-phosphogluconate dehydrogenase, NAD-binding YP_001220155.1 PFAM: General substrate transporter; major facilitator superfamily MFS_1 YP_001220156.1 PFAM: beta-lactamase domain protein YP_001220157.1 PFAM: short-chain dehydrogenase/reductase SDR; KR YP_001220158.1 PFAM: NADP oxidoreductase, coenzyme F420-dependent; 6-phosphogluconate dehydrogenase, NAD-binding YP_001220159.1 PFAM: Cupin 2, conserved barrel domain protein YP_001220160.1 PFAM: Carboxymuconolactone decarboxylase YP_001220161.1 PFAM: NIPSNAP family containing protein YP_001220163.1 PFAM: transposase IS3/IS911 family protein YP_001220164.1 PFAM: Integrase, catalytic region YP_001220165.1 PFAM: transposase IS116/IS110/IS902 family protein YP_001220167.1 PFAM: aminotransferase, class V YP_001220168.1 PFAM: Bile acid:sodium symporter YP_001220169.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA YP_001220170.1 PFAM: L-carnitine dehydratase/bile acid-inducible protein F YP_001220171.1 PFAM: regulatory protein GntR, HTH; GntR domain protein YP_001220172.1 PFAM: cytochrome B561 YP_001220173.1 PFAM: transposase, IS4 family protein YP_001220176.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001220177.1 PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; NmrA family protein; Male sterility C-terminal domain YP_001220181.1 PFAM: phage integrase family protein; phage integrase domain protein SAM domain protein YP_001220185.1 PFAM: Cobyrinic acid a,c-diamide synthase YP_001220186.1 PFAM: plasmid encoded RepA protein YP_001220192.1 PFAM: HipA domain protein YP_001220198.1 PFAM: helix-turn-helix domain protein YP_001220200.1 TIGRFAM: prevent-host-death family protein YP_001220201.1 PFAM: protein of unknown function DUF805 YP_001220202.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001220203.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001220204.1 PFAM: inner-membrane translocator YP_001220205.1 PFAM: inner-membrane translocator YP_001220206.1 PFAM: Extracellular ligand-binding receptor YP_001220207.1 PFAM: Cyclopropane-fatty-acyl-phospholipid synthase; Methyltransferase type 11; Methyltransferase type 12 YP_001220208.1 PFAM: CBS domain containing protein; Cl- channel, voltage-gated family protein YP_001220211.1 PFAM: major facilitator superfamily MFS_1 YP_001220212.1 PFAM: beta-lactamase domain protein YP_001220213.1 PFAM: Rhodanese domain protein; regulatory protein, ArsR YP_001220214.1 PFAM: putative transposase YP_001220215.1 PFAM: phage integrase family protein; phage integrase domain protein SAM domain protein YP_001220216.1 PFAM: cytochrome c, class I YP_001220220.1 PFAM: peptidase U32 YP_001220221.1 PFAM: peptidase U32 YP_001220222.1 PFAM: Endoribonuclease L-PSP YP_001220223.1 with PdxT forms pyridoxal 5'-phosphate from glutamine, either ribose 5-phosphate or ribulose 5-phosphate, and either glyceraldehyde 3-phosphate or dihydroxyacetone phosphate YP_001220224.1 with PdxST is involved in the biosynthesis of pyridoxal 5'-phosphate; PdxT catalyzes the hydrolysis of glutamine to glutamate and ammonia; PdxS utilizes the ammonia to synthesize pyridoxal 5'-phosphate YP_001220225.1 Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates YP_001220226.1 TIGRFAM: anaerobic ribonucleoside-triphosphate reductase activating protein; PFAM: Radical SAM domain protein YP_001220227.1 PFAM: transposase, IS4 family protein YP_001220228.1 PFAM: transposase, IS4 family protein YP_001220229.1 PFAM: IstB domain protein ATP-binding protein; IstB ATP binding N-terminal domain protein; SMART: AAA ATPase YP_001220230.1 PFAM: Integrase, catalytic region YP_001220231.1 PFAM: transposase, IS204/IS1001/IS1096/IS1165 family protein YP_001220232.1 TIGRFAM: potassium-transporting ATPase, A subunit; PFAM: K+ transporting ATPase, A subunit YP_001220233.1 TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; K+-transporting ATPase, B subunit; PFAM: Haloacid dehalogenase domain protein hydrolase; E1-E2 ATPase-associated domain protein YP_001220234.1 TIGRFAM: potassium-transporting ATPase, C subunit; PFAM: K+ transporting ATPase, KdpC subunit YP_001220237.1 PFAM: ATP-binding region, ATPase domain protein; histidine kinase A domain protein; Osmosensitive K+ channel His kinase sensor; UspA domain protein YP_001220238.1 PFAM: response regulator receiver; transcriptional regulator domain protein YP_001220240.1 PFAM: transposase Tn3 family protein YP_001220241.1 PFAM: Resolvase, N-terminal domain YP_001220244.1 PFAM: Resolvase, N-terminal domain YP_001220245.1 PFAM: transposase, IS4 family protein YP_001220247.1 PFAM: phage integrase family protein; phage integrase domain protein SAM domain protein YP_001220248.1 PFAM: phage integrase family protein YP_001220249.1 PFAM: phage integrase family protein YP_001220250.1 PFAM: domain of unknown function DUF1738 YP_001220251.1 PFAM: Integrase, catalytic region YP_001220252.1 PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase YP_001220253.1 PFAM: PilT protein domain protein YP_001220254.1 PFAM: Rv0623 family protein transcription factor YP_001220255.1 PFAM: NERD domain protein YP_001220257.1 PFAM: Cobyrinic acid a,c-diamide synthase YP_001220258.1 PFAM: protein of unknown function DUF891 YP_001220259.1 PFAM: helix-turn-helix domain protein YP_001220260.1 PFAM: replication protein C YP_001220262.1 PFAM: Lytic transglycosylase, catalytic YP_001220263.1 PFAM: VIRB2 type IV secretion fmaily protein YP_001220264.1 PFAM: type IV secretory pathway, VirB3 family protein YP_001220265.1 TIGRFAM: type IV secretion/conjugal transfer ATPase, VirB4 family; PFAM: CagE, TrbE, VirB component of type IV transporter system YP_001220266.1 PFAM: type IV secretion system family protein YP_001220267.1 PFAM: TrbL/VirB6 plasmid conjugal transfer protein YP_001220268.1 PFAM: VirB8 family protein YP_001220269.1 PFAM: Conjugal transfer protein TrbG/VirB9/CagX YP_001220270.1 PFAM: conjugation TrbI family protein YP_001220272.1 ATPase YP_001220273.1 VirD4 family YP_001220274.1 PFAM: regulatory protein, AsnC/Lrp family YP_001220275.1 PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit YP_001220276.1 TIGRFAM: amidohydrolase; PFAM: peptidase M20 YP_001220277.1 allantoate amidohydrolase and N-carbamoyl-L-amino acid amidohydrolase are very similar; the allantoate amidohydrolase from Escherichia coli forms a dimer and binds zinc ions for catalytic activity and catalyzes the conversion of allantoate to (S)-ureidoglycolate and ammonia; carbamoyl amidohydrolase from Bacillus sp. converts N-carbamoyl amino acids to amino acids, ammonia, and carbon dioxide YP_001220278.1 PFAM: UMUC domain protein DNA-repair protein YP_001220280.1 PFAM: protein of unknown function DUF159 YP_001220283.1 TIGRFAM: helicase, RecD/TraA family; SMART: Helix-hairpin-helix DNA-binding, class 1; AAA ATPase YP_001220284.1 PFAM: aldehyde dehydrogenase YP_001220292.1 TIGRFAM: CitB domain protein YP_001220293.1 PFAM: Resolvase, N-terminal domain; Resolvase helix-turn-helix domain protein YP_001220295.1 PFAM: GCN5-related N-acetyltransferase YP_001220297.1 PFAM: Relaxase/mobilization nuclease family protein YP_001220302.1 PFAM: Resolvase, N-terminal domain YP_001220303.1 PFAM: protein of unknown function DUF156 YP_001220304.1 PFAM: natural resistance-associated macrophage protein YP_001220306.1 PFAM: MgtC/SapB transporter YP_001220307.1 PFAM: transposase Tn3 family protein YP_001220308.1 PFAM: transposase Tn3 family protein YP_001220309.1 PFAM: transposase, mutator type YP_001220310.1 PFAM: Resolvase, N-terminal domain YP_001220314.1 TIGRFAM: transposase, IS605 OrfB family; PFAM: putative transposase, IS891/IS1136/IS1341 family; transposase, IS605 OrfB YP_001220317.1 PFAM: replication protein C YP_001220321.1 PFAM: DNA mismatch endonuclease vsr YP_001220322.1 TIGRFAM: DNA-cytosine methyltransferase; PFAM: C-5 cytosine-specific DNA methylase YP_001220328.1 PFAM: plasmid stabilization system YP_001220329.1 PFAM: protein of unknown function DUF1555 YP_001220331.1 PFAM: Integrase, catalytic region YP_001220332.1 PFAM: IstB domain protein ATP-binding protein; IstB ATP binding N-terminal domain protein; SMART: AAA ATPase YP_001220333.1 PFAM: transposase, IS111A/IS1328/IS1533; transposase IS116/IS110/IS902 family protein YP_001220336.1 PFAM: PemK family protein YP_001220337.1 PFAM: SpoVT/AbrB domain protein YP_001220341.1 PFAM: transposase Tn3 family protein YP_001220342.1 PFAM: Resolvase, N-terminal domain YP_001220343.1 PFAM: General substrate transporter; major facilitator superfamily MFS_1 YP_001220344.1 PFAM: TonB-dependent receptor YP_001220345.1 PFAM: MotA/TolQ/ExbB proton channel YP_001220347.1 PFAM: transposase, mutator type YP_001220348.1 PFAM: transposase, mutator type YP_001220350.1 PFAM: transposase, mutator type YP_001220359.1 PFAM: protein of unknown function DUF29 YP_001220361.1 PFAM: plasmid stabilization system YP_001220364.1 PFAM: MobA/MobL protein YP_001220369.1 PFAM: protein of unknown function DUF29 YP_001233149.1 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself. YP_001233150.1 PFAM: putative esterase YP_001233151.1 PFAM: Cold-shock protein, DNA-binding; SMART: Cold shock protein YP_001233152.1 PFAM: regulatory protein, MerR YP_001233153.1 TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase YP_001233154.1 PFAM: Enoyl-CoA hydratase/isomerase; 3-hydroxyacyl-CoA dehydrogenase domain protein; 3-hydroxyacyl-CoA dehydrogenase, NAD-binding YP_001233155.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain YP_001233156.1 PFAM: PEBP family protein YP_001233157.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001233159.1 PFAM: regulatory protein, LysR YP_001233160.1 PFAM: TspO/MBR family protein YP_001233162.1 PFAM: GPR1/FUN34/yaaH family protein YP_001233163.1 TIGRFAM: twin-arginine translocation protein, TatA/E family subunit; PFAM: sec-independent translocation protein mttA/Hcf106 YP_001233164.1 TIGRFAM: twin-arginine translocation protein, TatA/E family subunit; PFAM: sec-independent translocation protein mttA/Hcf106 YP_001233165.1 catalyzes the formation of diketo methylthiopentyl phosphate from methylribulose phosphate in the methionine salvage pathway YP_001233166.1 PFAM: Acireductone dioxygenase, ARD YP_001233167.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; 2,3-diketo-5-methylthio-1-phosphopentane phosphatase; PFAM: Haloacid dehalogenase domain protein hydrolase YP_001233168.1 TIGRFAM: apolipoprotein N-acyltransferase; PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase YP_001233169.1 PFAM: helix-turn-helix domain protein YP_001233170.1 PFAM: ribulose-phosphate 3-epimerase YP_001233171.1 PFAM: Heparinase II/III family protein YP_001233172.1 TIGRFAM: UDP-glucose 4-epimerase; PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; NmrA family protein; Male sterility C-terminal domain; KR YP_001233173.1 PFAM: glycosyl transferase, group 1 YP_001233174.1 PFAM: CreA family protein YP_001233175.1 involved in de novo purine biosynthesis YP_001233176.1 PFAM: Carboxymuconolactone decarboxylase YP_001233177.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling YP_001233178.1 Catalyzes the formation of (d)CDP from ATP and (d)CMP YP_001233179.1 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis YP_001233182.1 PFAM: L-carnitine dehydratase/bile acid-inducible protein F YP_001233184.1 TIGRFAM: putative ribonuclease BN; PFAM: ribonuclease BN YP_001233185.1 TIGRFAM: VacB and RNase II family 3'-5' exoribonuclease; ribonuclease R; PFAM: ribonuclease II; SMART: RNA binding S1 domain protein YP_001233186.1 PFAM: PDZ/DHR/GLGF domain protein; peptidase S41 YP_001233187.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif YP_001233188.1 TIGRFAM: lipid-A-disaccharide synthase; PFAM: glycosyl transferase, family 19 YP_001233189.1 PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase YP_001233191.1 PFAM: cytochrome c, class I YP_001233192.1 catalyzes the formation of 5-aminolevulinate from succinyl-CoA and glycine YP_001233193.1 flavin dependent thymidylate synthase; ThyX; thymidylate synthase complementing protein; catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate; the enzyme from Mycobacterium tuberculosis forms homotetramers; uses FAD as a cofactor YP_001233195.1 PFAM: Cobyrinic acid a,c-diamide synthase YP_001233196.1 TIGRFAM: carbohydrate kinase, YjeF related protein; PFAM: protein of unknown function UPF0031; YjeF-family N-terminal domain protein YP_001233197.1 TIGRFAM: glycine cleavage system T protein; PFAM: glycine cleavage T protein (aminomethyl transferase); Glycine cleavage T-protein, C-terminal barrel YP_001233198.1 TIGRFAM: glycine cleavage system H protein; PFAM: glycine cleavage H-protein YP_001233199.1 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine YP_001233200.1 PFAM: Lipocalin family protein YP_001233201.1 PFAM: peptidase S49 YP_001233202.1 MraZ; UPF0040; crystal structure shows similarity to AbrB YP_001233203.1 TIGRFAM: S-adenosyl-methyltransferase MraW; PFAM: methyltransferase YP_001233205.1 PFAM: penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain YP_001233206.1 involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate YP_001233207.1 TIGRFAM: UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase, middle domain protein YP_001233208.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan YP_001233209.1 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation YP_001233210.1 PFAM: cell cycle protein YP_001233211.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis YP_001233212.1 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis YP_001233213.1 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis YP_001233214.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli YP_001233215.1 PFAM: cell division protein FtsQ; Polypeptide-transport-associated domain protein, FtsQ-type YP_001233216.1 PFAM: cell division protein FtsA YP_001233217.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function YP_001233219.1 PFAM: ComEC/Rec2-related protein YP_001233220.1 PFAM: glycosyl transferase, family 2 YP_001233221.1 PFAM: sugar transferase YP_001233222.1 PFAM: GtrA family protein YP_001233223.1 PFAM: ferredoxin; [2Fe-2S]-binding domain protein YP_001233224.1 PFAM: aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead; aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding YP_001233225.1 PFAM: molybdopterin dehydrogenase, FAD-binding YP_001233226.1 possibly involved in transport of pyrroloquinoline quinone transport YP_001233227.1 Required in the synthesis of PPQ, but its exact function is unknown YP_001233228.1 PFAM: coenzyme PQQ synthesis D YP_001233229.1 TIGRFAM: coenzyme PQQ biosynthesis protein E; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB YP_001233230.1 TIGRFAM: RNA methyltransferase, TrmH family, group 3; PFAM: tRNA/rRNA methyltransferase (SpoU); RNA 2-O ribose methyltransferase, substrate binding YP_001233233.1 PFAM: isochorismatase hydrolase YP_001233234.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR YP_001233235.1 catalyzes the formation of 3-methyl-2-oxobutanoate from 2,3,-dihydroxy-3-methylbutanoate YP_001233237.1 TIGRFAM: Cu(I)-responsive transcriptional regulator; PFAM: regulatory protein, MerR YP_001233238.1 PFAM: acriflavin resistance protein YP_001233239.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein YP_001233240.1 TIGRFAM: RND efflux system, outer membrane lipoprotein, NodT family; PFAM: outer membrane efflux protein YP_001233241.1 PFAM: regulatory protein, TetR YP_001233242.1 PFAM: PaaX domain protein; PaaX domain protein, C-terminal domain YP_001233243.1 PFAM: transposase, IS4 family protein YP_001233245.1 PFAM: transposase, IS4 family protein YP_001233248.1 PFAM: transposase, IS4 family protein YP_001233249.1 PFAM: aminotransferase, class I and II YP_001233250.1 PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein YP_001233251.1 PFAM: Tetratricopeptide TPR_2 repeat protein YP_001233252.1 PFAM: protein of unknown function DUF1217 YP_001233255.1 PFAM: flagellin domain protein YP_001233256.1 TIGRFAM: flagellar hook-associated protein FlgK; PFAM: flagellar basal body rod protein; protein of unknown function DUF1078 domain protein YP_001233257.1 the hook connects flagellar basal body to the flagellar filament YP_001233260.1 PFAM: flagellar hook capping protein YP_001233262.1 PFAM: transposase, IS204/IS1001/IS1096/IS1165 family protein YP_001233263.1 PFAM: ROK family protein YP_001233264.1 PFAM: amine oxidase YP_001233265.1 PFAM: Squalene/phytoene synthase YP_001233266.1 PFAM: Squalene/phytoene synthase YP_001233267.1 PFAM: glycosyl transferase, family 2 YP_001233268.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; NmrA family protein; Male sterility C-terminal domain YP_001233270.1 PFAM: Transglycosylase-associated protein YP_001233271.1 PFAM: acyltransferase 3 YP_001233272.1 PFAM: HemY domain protein YP_001233274.1 PFAM: Uroporphyrinogen III synthase HEM4 YP_001233275.1 TIGRFAM: porphobilinogen deaminase; PFAM: Porphobilinogen deaminase YP_001233276.1 TIGRFAM: putative metalloendopeptidase, glycoprotease family; PFAM: peptidase M22, glycoprotease YP_001233277.1 TIGRFAM: glycogen/starch/alpha-glucan phosphorylase; PFAM: glycosyl transferase, family 35 YP_001233278.1 catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate YP_001233279.1 catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose YP_001233280.1 PFAM: acriflavin resistance protein YP_001233281.1 PFAM: acriflavin resistance protein YP_001233282.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein YP_001233283.1 TIGRFAM: RND efflux system, outer membrane lipoprotein, NodT family; PFAM: outer membrane efflux protein YP_001233284.1 PFAM: Phosphoglycerate mutase YP_001233285.1 PFAM: import inner membrane translocase, subunit Tim44 YP_001233286.1 PFAM: MltA domain protein; 3D domain protein YP_001233287.1 PFAM: protein of unknown function DUF224, cysteine-rich region domain protein YP_001233288.1 PFAM: K+ potassium transporter YP_001233291.1 PFAM: GCN5-related N-acetyltransferase YP_001233292.1 PFAM: protein of unknown function DUF6, transmembrane YP_001233293.1 PFAM: 3-hydroxyacyl-CoA dehydrogenase domain protein; 3-hydroxyacyl-CoA dehydrogenase, NAD-binding YP_001233294.1 PFAM: electron transfer flavoprotein beta-subunit; electron transfer flavoprotein, alpha subunit YP_001233295.1 PFAM: electron transfer flavoprotein beta-subunit YP_001233297.1 PFAM: glutamate-ammonia ligase adenylyltransferase YP_001233298.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein YP_001233299.1 PFAM: Disulphide bond formation protein DsbB YP_001233300.1 PFAM: Ubiquinone biosynthesis protein COQ7 YP_001233302.1 TIGRFAM: phasin family protein YP_001233303.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion YP_001233308.1 isomerizes methylthioribose-1-phosphate into methylthioribulose-1-phosphate; involved in methionine salvage pathway YP_001233310.1 PFAM: AAA ATPase, central domain protein; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase YP_001233311.1 TIGRFAM: pseudouridine synthase, RluA family; PFAM: RNA-binding S4 domain protein; pseudouridine synthase YP_001233312.1 PFAM: surface antigen (D15); surface antigen variable number repeat protein YP_001233313.1 PFAM: protein of unknown function DUF490 YP_001233314.1 PFAM: enolase YP_001233315.1 PFAM: Endoribonuclease L-PSP YP_001233317.1 PFAM: NADH:ubiquinone oxidoreductase 17.2 kD subunit YP_001233318.1 PFAM: Mammalian cell entry related domain protein YP_001233320.1 PFAM: OmpA/MotB domain protein YP_001233321.1 PFAM: surface antigen msp4 family protein; OmpA/MotB domain protein YP_001233324.1 PFAM: Ethyl tert-butyl ether degradation EthD YP_001233325.1 PFAM: pyruvate kinase YP_001233326.1 PFAM: protein of unknown function DUF1244 YP_001233328.1 catalyzes the formation of porphobilinogen from 5-aminolevulinate YP_001233329.1 TIGRFAM: tartrate dehydrogenase; PFAM: isocitrate/isopropylmalate dehydrogenase YP_001233331.1 PFAM: CHAD domain containing protein YP_001233332.1 TIGRFAM: ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; PFAM: ribonucleotide reductase large subunit; Ribonucleotide reductase large subunit, N terminal domain protein YP_001233333.1 PFAM: regulatory protein, LacI; periplasmic binding protein/LacI transcriptional regulator YP_001233334.1 TIGRFAM: phosphoenolpyruvate-protein phosphotransferase; PFAM: phosphocarrier HPr protein; PEP-utilizing enzyme; phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; PEP-utilising enzyme, mobile region; PEP-utilising enzyme domain protein YP_001233335.1 PFAM: PfkB domain protein YP_001233336.1 TIGRFAM: PTS system, fructose-specific, IIB subunnit; PTS system, fructose subfamily, IIC subunit; PFAM: phosphotransferase system, EIIC; phosphotransferase system PTS, fructose-specific IIB subunit YP_001233337.1 PFAM: thioesterase superfamily protein YP_001233338.1 TIGRFAM: 2-dehydropantoate 2-reductase; PFAM: Ketopantoate reductase ApbA/PanE, N-terminal domain protein; Ketopantoate reductase ApbA/PanE, C-terminal domain protein YP_001233340.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; pyridine nucleotide-disulphide oxidoreductase dimerisation region YP_001233341.1 PFAM: metallophosphoesterase; Radical SAM domain protein YP_001233342.1 PFAM: General substrate transporter; major facilitator superfamily MFS_1 YP_001233343.1 PFAM: dihydrodipicolinate synthetase YP_001233344.1 PFAM: aldehyde dehydrogenase YP_001233345.1 PFAM: Dimethylmenaquinone methyltransferase YP_001233346.1 PFAM: peptidase M48, Ste24p YP_001233347.1 PFAM: heat shock protein Hsp20 YP_001233352.1 PFAM: glycosyl transferase, group 1 YP_001233353.1 PFAM: glycosyl transferase, group 1 YP_001233354.1 PFAM: ABC transporter, transmembrane region; ABC transporter related; SMART: AAA ATPase YP_001233356.1 PFAM: Phosphoglycerate mutase YP_001233357.1 PFAM: UDP-glucose/GDP-mannose dehydrogenase YP_001233358.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR YP_001233359.1 Catalyzes the conversion of citrate to isocitrate YP_001233360.1 TIGRFAM: heme exporter protein CcmA; PFAM: ABC transporter related; SMART: AAA ATPase YP_001233361.1 PFAM: cytochrome c-type biogenesis protein CcmB YP_001233362.1 PFAM: creatinase; peptidase M24 YP_001233363.1 PFAM: protein of unknown function DUF1127 YP_001233364.1 PFAM: methyltransferase small; ribosomal L11 methyltransferase YP_001233365.1 PFAM: UvrD/REP helicase YP_001233366.1 TIGRFAM: 5,10-methylenetetrahydrofolate reductase; PFAM: methylenetetrahydrofolate reductase YP_001233367.1 PFAM: VacJ family lipoprotein YP_001233368.1 PFAM: toluene tolerance family protein YP_001233369.1 PFAM: protein of unknown function DUF150 YP_001233370.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination YP_001233371.1 PFAM: protein of unknown function DUF448 YP_001233372.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex YP_001233373.1 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock YP_001233374.1 TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; PFAM: SUA5 domain protein; SUA5/yciO/yrdC, N-terminal domain YP_001233375.1 PFAM: glycosyl transferase, group 1 YP_001233376.1 TIGRFAM: methyltransferase FkbM family YP_001233378.1 PFAM: ribosomal protein L21 YP_001233379.1 involved in the peptidyltransferase reaction during translation YP_001233380.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication YP_001233381.1 catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis YP_001233382.1 PFAM: MscS Mechanosensitive ion channel YP_001233384.1 Conjugates Arg from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate YP_001233385.1 PFAM: RDD domain containing protein YP_001233386.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP YP_001233387.1 PFAM: Glutathione S-transferase, N-terminal domain; Glutathione S-transferase, C-terminal domain YP_001233388.1 PFAM: Phosphoglycerate mutase YP_001233389.1 PFAM: iron-containing alcohol dehydrogenase YP_001233390.1 PFAM: Amidase YP_001233392.1 PFAM: UbiE/COQ5 methyltransferase; Methyltransferase type 11; Methyltransferase type 12 YP_001233393.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene YP_001233395.1 PFAM: peptidase S11, D-alanyl-D-alanine carboxypeptidase 1; Penicillin-binding protein 5 domain protein YP_001233396.1 TIGRFAM: signal peptidase I; PFAM: peptidase S24, S26A and S26B YP_001233397.1 PFAM: ribonuclease III; double-stranded RNA binding domain protein YP_001233398.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome YP_001233399.1 PFAM: acyl-CoA dehydrogenase domain protein YP_001233400.1 PFAM: acyl-CoA dehydrogenase domain protein YP_001233401.1 PFAM: AMP-dependent synthetase and ligase YP_001233402.1 PFAM: Enoyl-CoA hydratase/isomerase; 3-hydroxyacyl-CoA dehydrogenase domain protein; 3-hydroxyacyl-CoA dehydrogenase, NAD-binding YP_001233404.1 PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein YP_001233405.1 PFAM: sulfotransferase; Tetratricopeptide TPR_4 YP_001233406.1 PFAM: Rubrerythrin; protein of unknown function DUF125, transmembrane YP_001233407.1 PFAM: 2-nitropropane dioxygenase, NPD YP_001233408.1 PFAM: Glutathione S-transferase, N-terminal domain YP_001233409.1 PFAM: glycine cleavage T protein (aminomethyl transferase); Glycine cleavage T-protein, C-terminal barrel YP_001233410.1 PFAM: glycosyl transferase, family 9 YP_001233411.1 PFAM: glycosyl transferase, group 1 YP_001233412.1 TIGRFAM: asparagine synthase (glutamine-hydrolyzing); PFAM: glutamine amidotransferase, class-II; asparagine synthase YP_001233413.1 Catalyzes the reversible hydrolysis of the amide bond within dihydroorotate. This metabolic intermediate is required for the biosynthesis of pyrimidine nucleotides YP_001233414.1 PFAM: regulatory protein, MerR YP_001233415.1 TIGRFAM: integration host factor, alpha subunit; PFAM: histone family protein DNA-binding protein YP_001233416.1 TIGRFAM: 3-oxoacyl-(acyl-carrier-protein) synthase III; PFAM: 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal domain protein; 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III YP_001233417.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY YP_001233418.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not YP_001233419.1 PFAM: SmpA/OmlA domain protein YP_001233421.1 TIGRFAM: succinic semialdehyde dehydrogenase; PFAM: aldehyde dehydrogenase YP_001233422.1 PFAM: phage integrase family protein YP_001233424.1 TIGRFAM: DNA binding domain, excisionase family YP_001233425.1 PFAM: phage integrase family protein YP_001233426.1 PFAM: phage integrase family protein YP_001233428.1 PFAM: GCN5-related N-acetyltransferase YP_001233429.1 PFAM: IstB domain protein ATP-binding protein; IstB ATP binding N-terminal domain protein; SMART: AAA ATPase YP_001233430.1 PFAM: Integrase, catalytic region YP_001233432.1 PFAM: transposase IS116/IS110/IS902 family protein YP_001233434.1 PFAM: transposase, mutator type YP_001233435.1 PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes; DegT/DnrJ/EryC1/StrS aminotransferase; aromatic amino acid beta-eliminating lyase/threonine aldolase YP_001233436.1 PFAM: glycosyl transferase, group 1 YP_001233437.1 PFAM: glycosyl transferase, group 1 YP_001233438.1 PFAM: glycosyl transferase, group 1 YP_001233440.1 TIGRFAM: methyltransferase FkbM family YP_001233441.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug YP_001233442.1 TIGRFAM: TonB family protein YP_001233445.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001233446.1 TIGRFAM: efflux transporter, RND family, MFP subunit YP_001233447.1 PFAM: protein of unknown function DUF214 YP_001233448.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001233449.1 PFAM: protein of unknown function DUF190 YP_001233450.1 TIGRFAM: CrcB protein; PFAM: Camphor resistance CrcB protein YP_001233451.1 PFAM: Arsenical pump membrane protein; Citrate transporter YP_001233452.1 PFAM: ABC transporter related; protein of unknown function DUF214; SMART: AAA ATPase YP_001233453.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein YP_001233454.1 PFAM: acriflavin resistance protein YP_001233455.1 TIGRFAM: efflux transporter, RND family, MFP subunit YP_001233456.1 PFAM: outer membrane efflux protein YP_001233457.1 PFAM: response regulator receiver; transcriptional regulator domain protein YP_001233458.1 PFAM: ATP-binding region, ATPase domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein YP_001233459.1 SMART: helix-turn-helix domain protein YP_001233460.1 PFAM: regulatory protein, MarR YP_001233461.1 PFAM: CBS domain containing protein; Cl- channel, voltage-gated family protein YP_001233462.1 catalyzes the formation of pyruvate from 2,3-diaminopropionate YP_001233464.1 PFAM: inner-membrane translocator YP_001233465.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001233466.1 PFAM: protein of unknown function DUF861, cupin_3; Cupin 2, conserved barrel domain protein YP_001233467.1 PFAM: monooxygenase, FAD-binding YP_001233469.1 Required in the synthesis of PPQ, but its exact function is unknown YP_001233470.1 PFAM: NUDIX hydrolase YP_001233471.1 TIGRFAM: phenazine biosynthesis protein PhzF family; PFAM: Phenazine biosynthesis PhzC/PhzF protein YP_001233472.1 TIGRFAM: hydrogenase assembly chaperone hypC/hupF; PFAM: hydrogenase expression/formation protein (HUPF/HYPC) YP_001233473.1 PFAM: hydrogenase formation HypD protein YP_001233474.1 TIGRFAM: [NiFe] hydrogenase maturation protein HypF; PFAM: acylphosphatase; SUA5/yciO/yrdC, N-terminal domain; zinc finger, HypF domain protein YP_001233475.1 TIGRFAM: hydrogenase expression/formation protein HypE; PFAM: AIR synthase related protein; AIR synthase related protein domain protein YP_001233476.1 TIGRFAM: hydrogenase accessory protein HypB; PFAM: cobalamin synthesis protein, P47K YP_001233477.1 TIGRFAM: hydrogenase nickel insertion protein HypA; PFAM: hydrogenase expression/synthesis, HypA YP_001233478.1 PFAM: Rubredoxin-type Fe(Cys)4 protein YP_001233479.1 PFAM: HupH hydrogenase expression protein YP_001233480.1 PFAM: hydrogenase-1 expression HyaE YP_001233481.1 TIGRFAM: hydrogenase maturation protease; hydrogenase expression/formation protein; PFAM: peptidase M52, hydrogen uptake protein YP_001233482.1 TIGRFAM: Ni/Fe-hydrogenase, b-type cytochrome subunit; PFAM: cytochrome B561 YP_001233483.1 PFAM: nickel-dependent hydrogenase, large subunit YP_001233484.1 TIGRFAM: hydrogenase (NiFe) small subunit HydA; PFAM: NADH ubiquinone oxidoreductase, 20 kDa subunit; Nickel-iron dehydrogenase small subunit, N-terminal domain protein YP_001233485.1 PFAM: protein of unknown function DUF1486 YP_001233486.1 PFAM: cyclase/dehydrase YP_001233487.1 PFAM: UbiA prenyltransferase YP_001233488.1 PFAM: Rhodanese domain protein YP_001233489.1 PFAM: Polysulphide reductase, NrfD YP_001233490.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001233491.1 PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region YP_001233492.1 PFAM: Rhodanese domain protein YP_001233494.1 PFAM: high-affinity nickel-transporter YP_001233497.1 PFAM: Hsp33 protein YP_001233498.1 TIGRFAM: cytidyltransferase-related domain; rfaE bifunctional protein; PFAM: cytidylyltransferase; PfkB domain protein YP_001233499.1 PFAM: protein of unknown function DUF344 YP_001233500.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001233501.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001233502.1 PFAM: inner-membrane translocator YP_001233503.1 PFAM: inner-membrane translocator YP_001233504.1 PFAM: Extracellular ligand-binding receptor YP_001233505.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily YP_001233506.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily YP_001233507.1 PFAM: OmpA/MotB domain protein YP_001233509.1 TIGRFAM: tRNA(Ile)-lysidine synthetase; PFAM: PP-loop domain protein YP_001233510.1 TIGRFAM: ATP-dependent metalloprotease FtsH; PFAM: peptidase M41; AAA ATPase, central domain protein; peptidase M41, FtsH extracellular; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase YP_001233511.1 PFAM: NADP oxidoreductase, coenzyme F420-dependent; 6-phosphogluconate dehydrogenase, NAD-binding YP_001233512.1 PFAM: Enoyl-CoA hydratase/isomerase YP_001233513.1 PFAM: 3' exoribonuclease; RNA binding S1 domain protein; KH, type 1, domain protein; SMART: KH domain protein YP_001233514.1 PFAM: major facilitator superfamily MFS_1 YP_001233516.1 PFAM: DoxX family protein YP_001233517.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA YP_001233518.1 TIGRFAM: peptide deformylase; PFAM: formylmethionine deformylase YP_001233519.1 TIGRFAM: rpsU-divergently transcribed protein; PFAM: COQ9 domain protein YP_001233520.1 TIGRFAM: Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; PFAM: monooxygenase, FAD-binding; FAD dependent oxidoreductase YP_001233521.1 TIGRFAM: ammonium transporter; PFAM: Rh family protein/ammonium transporter YP_001233522.1 PFAM: cell divisionFtsK/SpoIIIE YP_001233524.1 catalyzes the formation of glycerone phosphate and D-glyceraldehyde 3-phosphate from D-fructose 1,6-bisphosphate YP_001233525.1 TIGRFAM: thiamine-phosphate pyrophosphorylase; PFAM: thiamine monophosphate synthase YP_001233527.1 PFAM: glycosyl transferase, family 2 YP_001233530.1 SMART: Fucolectin tachylectin-4 pentraxin-1 YP_001233531.1 PFAM: glycosyltransferase sugar-binding region containing DXD motif YP_001233532.1 TIGRFAM: ribonuclease, Rne/Rng family YP_001233534.1 FOG: Transposase-like protein YP_001233535.1 PFAM: TrkA-N domain protein; Ion transport protein; Ion transport 2 domain protein YP_001233536.1 TIGRFAM: phosphoribosylformylglycinamidine synthase, purS; PFAM: phosphoribosylformylglycinamidine synthetase PurS YP_001233537.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase YP_001233538.1 PFAM: H+-transporting two-sector ATPase, B/B' subunit YP_001233539.1 PFAM: H+-transporting two-sector ATPase, B/B' subunit YP_001233540.1 PFAM: H+-transporting two-sector ATPase, C subunit YP_001233541.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0 YP_001233543.1 TIGRFAM: chromosome segregation protein SMC; PFAM: SMC domain protein YP_001233545.1 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis YP_001233547.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents YP_001233548.1 PFAM: Colicin V production protein YP_001233549.1 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway YP_001233550.1 TIGRFAM: peptide methionine sulfoxide reductase; PFAM: Methionine sulfoxide reductase A YP_001233551.1 PFAM: protein of unknown function DUF1150 YP_001233552.1 PFAM: heat shock protein Hsp20 YP_001233553.1 TIGRFAM: peptide deformylase; PFAM: formylmethionine deformylase YP_001233554.1 TIGRFAM: methionyl-tRNA formyltransferase; PFAM: formyl transferase domain protein YP_001233555.1 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability YP_001233556.1 TIGRFAM: translation initiation factor IF-3; PFAM: initiation factor 3 YP_001233558.1 TIGRFAM: exodeoxyribonuclease III Xth; PFAM: Endonuclease/exonuclease/phosphatase YP_001233559.1 PFAM: fumarylacetoacetate (FAA) hydrolase YP_001233560.1 PFAM: peptidase C26 YP_001233561.1 PFAM: outer membrane lipoprotein carrier protein LolA YP_001233562.1 PFAM: regulatory protein, MarR YP_001233563.1 PFAM: peptidase M17, leucyl aminopeptidase domain protein YP_001233564.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision YP_001233567.1 PFAM: protein of unknown function DUF152 YP_001233568.1 PFAM: protein of unknown function DUF185 YP_001233569.1 PFAM: prolipoprotein diacylglyceryl transferase YP_001233570.1 TIGRFAM: ADP-L-glycero-D-manno-heptose-6-epimerase; PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase YP_001233571.1 PFAM: protein of unknown function DUF526 YP_001233572.1 TIGRFAM: maf protein; PFAM: Maf family protein YP_001233573.1 PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein YP_001233574.1 PFAM: protein of unknown function DUF45 YP_001233575.1 PFAM: protein of unknown function UPF0153 YP_001233576.1 PFAM: protein of unknown function DUF500 YP_001233577.1 PFAM: Phosphoglycerate mutase YP_001233578.1 PFAM: ABC-2 type transporter YP_001233579.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001233580.1 TIGRFAM: methionine biosynthesis protein MetW; PFAM: Methionine biosynthesis MetW protein; Methyltransferase type 11; Methyltransferase type 12 YP_001233581.1 Catalyzes the conversion of acetyl-CoA and L-homoserine to CoA and O-acetyl-L-homoserine YP_001233582.1 TIGRFAM: chorismate mutase; PFAM: Chorismate mutase YP_001233583.1 catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis YP_001233584.1 PFAM: Prephenate dehydrogenase; NADP oxidoreductase, coenzyme F420-dependent YP_001233585.1 catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs YP_001233586.1 PFAM: ribosomal protein S15 YP_001233587.1 PFAM: protein of unknown function UPF0005 YP_001233588.1 TIGRFAM: phosphocarrier, HPr family; PFAM: phosphocarrier HPr protein YP_001233589.1 PFAM: PTS system fructose subfamily IIA component YP_001233590.1 PFAM: uncharacterised P-loop ATPase protein UPF0042 YP_001233594.1 PFAM: response regulator receiver; transcriptional regulator domain protein YP_001233595.1 PFAM: ATP-binding region, ATPase domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein YP_001233596.1 PFAM: General substrate transporter; major facilitator superfamily MFS_1 YP_001233597.1 TIGRFAM: outer membrane autotransporter barrel domain; PFAM: peptidase S8 and S53, subtilisin, kexin, sedolisin; Autotransporter beta- domain protein YP_001233598.1 PFAM: protein of unknown function DUF1345 YP_001233599.1 TIGRFAM: FGGY-family pentulose kinase; PFAM: carbohydrate kinase, FGGY YP_001233600.1 PFAM: PfkB domain protein YP_001233601.1 PFAM: regulatory protein, DeoR; Helix-turn-helix, type 11 domain protein YP_001233602.1 PFAM: extracellular solute-binding protein, family 1 YP_001233603.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001233604.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001233605.1 PFAM: ABC transporter related; TOBE domain protein; Transport-associated OB domain protein; SMART: AAA ATPase YP_001233606.1 PFAM: short-chain dehydrogenase/reductase SDR; KR YP_001233607.1 PFAM: short-chain dehydrogenase/reductase SDR; KR YP_001233608.1 TIGRFAM: glucose-6-phosphate 1-dehydrogenase; PFAM: glucose-6-phosphate dehydrogenase YP_001233609.1 catalyzes the formation of 2-dehydro-3-deoxy-6-phospho-D-gluconate from 6-phospho-D-gluconate YP_001233610.1 TIGRFAM: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; PFAM: KDPG and KHG aldolase YP_001233611.1 TIGRFAM: sugar transporter; PFAM: General substrate transporter; major facilitator superfamily MFS_1 YP_001233613.1 PFAM: cyclase/dehydrase; carbon monoxide dehydrogenase subunit G YP_001233614.1 PFAM: ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase YP_001233615.1 PFAM: VWA containing CoxE family protein; SMART: von Willebrand factor, type A YP_001233616.1 PFAM: protein of unknown function DUF182 YP_001233619.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding YP_001233620.1 TIGRFAM: phenylacetate-CoA ligase YP_001233621.1 TIGRFAM: phenylacetic acid degradation protein PaaD; PFAM: thioesterase superfamily protein YP_001233622.1 PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein YP_001233624.1 PFAM: type II and III secretion system protein YP_001233625.1 PFAM: Extracellular ligand-binding receptor YP_001233626.1 PFAM: inner-membrane translocator YP_001233627.1 PFAM: inner-membrane translocator YP_001233628.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001233630.1 PFAM: transposase, IS204/IS1001/IS1096/IS1165 family protein YP_001233633.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; CHASE4 domain protein YP_001233635.1 PFAM: ThiJ/PfpI domain protein YP_001233636.1 PFAM: helix-turn-helix- domain containing protein, AraC type; ThiJ/PfpI domain protein YP_001233637.1 catalyzes the formation of acetoacetate from 3-hydroxybutyrate YP_001233638.1 converts acetoacetate to acetone and carbon dioxide YP_001233639.1 PFAM: Patatin YP_001233640.1 PFAM: penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain YP_001233642.1 PFAM: protein of unknown function DUF395, YeeE/YedE YP_001233643.1 PFAM: Rhodanese domain protein YP_001233644.1 PFAM: regulatory protein, LacI; periplasmic binding protein/LacI transcriptional regulator YP_001233645.1 TIGRFAM: xylulokinase; PFAM: carbohydrate kinase, FGGY YP_001233646.1 PFAM: periplasmic binding protein/LacI transcriptional regulator YP_001233647.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001233648.1 PFAM: inner-membrane translocator YP_001233649.1 PFAM: histone family protein DNA-binding protein YP_001233650.1 PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility C-terminal domain YP_001233651.1 TIGRFAM: GDP-mannose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; dTDP-4-dehydrorhamnose reductase YP_001233652.1 PFAM: aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead; aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding YP_001233653.1 PFAM: molybdopterin dehydrogenase, FAD-binding YP_001233654.1 PFAM: ferredoxin; [2Fe-2S]-binding domain protein YP_001233655.1 PFAM: regulatory protein, TetR YP_001233656.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase YP_001233657.1 PFAM: alpha/beta hydrolase fold YP_001233658.1 TIGRFAM: rare lipoprotein A; PFAM: Rare lipoprotein A YP_001233659.1 PFAM: protein of unknown function DUF1130 YP_001233660.1 PFAM: sulfotransferase YP_001233662.1 PFAM: flavin reductase domain protein, FMN-binding YP_001233663.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; Cache, type 2 domain protein YP_001233665.1 TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; GAF domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; SMART: PAC repeat-containing protein YP_001233669.1 SMART: helicase c2 YP_001233670.1 PFAM: Uracil-DNA glycosylase superfamily YP_001233671.1 PFAM: protein of unknown function DUF88 YP_001233672.1 TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK YP_001233673.1 Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits YP_001233674.1 TIGRFAM: RelA/SpoT family protein; PFAM: TGS domain protein; metal-dependent phosphohydrolase, HD sub domain; RelA/SpoT domain protein; SMART: metal-dependent phosphohydrolase, HD region YP_001233675.1 TIGRFAM: holo-acyl-carrier-protein synthase; PFAM: 4'-phosphopantetheinyl transferase YP_001233676.1 PFAM: (Uracil-5)-methyltransferase YP_001233677.1 catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis YP_001233678.1 PFAM: alpha/beta hydrolase fold YP_001233680.1 PFAM: FAD dependent oxidoreductase YP_001233681.1 PFAM: glutamine synthetase, catalytic region YP_001233682.1 PFAM: extracellular solute-binding protein, family 1 YP_001233683.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001233684.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001233685.1 TIGRFAM: spermidine/putrescine ABC transporter ATPase subunit; PFAM: ABC transporter related; TOBE domain protein; Transport-associated OB domain protein; SMART: AAA ATPase YP_001233686.1 TIGRFAM: alanine dehydrogenase; PFAM: alanine dehydrogenase/PNT domain protein YP_001233687.1 PFAM: helix-turn-helix domain protein; Cupin 2, conserved barrel domain protein YP_001233688.1 PFAM: aminotransferase class-III YP_001233689.1 PFAM: glutamine synthetase, catalytic region YP_001233690.1 PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB YP_001233691.1 TIGRFAM: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; PFAM: mannose-6-phosphate isomerase, type II; Nucleotidyl transferase; Cupin 2, conserved barrel domain protein YP_001233694.1 TIGRFAM: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; PFAM: 4-diphosphocytidyl-2C-methyl-D-erythritol synthase YP_001233695.1 zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis YP_001233696.1 TIGRFAM: ABC transporter, transmembrane region, type 1; PFAM: ABC transporter related; SMART: AAA ATPase YP_001233697.1 TIGRFAM: ABC transporter, transmembrane region, type 1; PFAM: ABC transporter related; SMART: AAA ATPase YP_001233698.1 TIGRFAM: pantoate--beta-alanine ligase; PFAM: Pantoate-beta-alanine ligase YP_001233699.1 PFAM: EAL domain protein YP_001233702.1 PFAM: ABC transporter related; SbmABacA family protein; ABC transporter domain protein; SMART: AAA ATPase YP_001233703.1 PFAM: glycerophosphoryl diester phosphodiesterase YP_001233704.1 PFAM: secretion protein HlyD family protein YP_001233705.1 TIGRFAM: drug resistance transporter, EmrB/QacA subfamily; PFAM: major facilitator superfamily MFS_1 YP_001233706.1 TIGRFAM: RND efflux system, outer membrane lipoprotein, NodT family; PFAM: outer membrane efflux protein YP_001233707.1 PFAM: luciferase family protein YP_001233708.1 Converts isocitrate to alpha ketoglutarate YP_001233709.1 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate YP_001233710.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein YP_001233711.1 PFAM: glycoside hydrolase, family 3 domain protein YP_001233712.1 PFAM: glycosyl transferase, family 2; type IV pilus assembly PilZ YP_001233713.1 catalyzes the hydrolysis of 1,4-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans YP_001233717.1 PFAM: transcriptional regulator domain protein YP_001233719.1 PFAM: cyclic nucleotide-binding; regulatory protein, Crp YP_001233720.1 PFAM: response regulator receiver; transcriptional regulator domain protein YP_001233721.1 TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001233722.1 PFAM: membrane-flanked domain YP_001233724.1 PFAM: helix-turn-helix domain protein; protein of unknown function DUF955 YP_001233725.1 Required for DNA replication; binds preferentially to single-stranded, linear DNA YP_001233726.1 TIGRFAM: riboflavin biosynthesis protein RibF; PFAM: Riboflavin kinase / FAD synthetase YP_001233727.1 PFAM: MaoC domain protein dehydratase YP_001233728.1 PFAM: glycosyl transferase, family 2 YP_001233730.1 PFAM: major facilitator superfamily MFS_1 YP_001233731.1 PFAM: ABC transporter, transmembrane region; ABC transporter related; SMART: AAA ATPase YP_001233733.1 PFAM: glycosyl transferase, group 1 YP_001233734.1 TIGRFAM: glucose-1-phosphate cytidylyltransferase; PFAM: Nucleotidyl transferase YP_001233735.1 TIGRFAM: CDP-glucose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility C-terminal domain YP_001233736.1 TIGRFAM: dTDP-4-dehydrorhamnose 3,5-epimerase; PFAM: dTDP-4-dehydrorhamnose 3,5-epimerase related YP_001233737.1 PFAM: Methyltransferase type 12; Methyltransferase domain protein; C-methyltransferase YP_001233739.1 PFAM: NAD-dependent epimerase/dehydratase; Male sterility C-terminal domain YP_001233740.1 PFAM: Cephalosporin hydroxylase YP_001233741.1 PFAM: chemotaxis sensory transducer; SMART: histidine kinase, HAMP region domain protein YP_001233742.1 PFAM: electron transport protein SCO1/SenC YP_001233746.1 PFAM: NADH/Ubiquinone/plastoquinone (complex I) YP_001233747.1 PFAM: NADH-ubiquinone oxidoreductase, chain 49kDa YP_001233748.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; NADH ubiquinone oxidoreductase, 20 kDa subunit YP_001233749.1 PFAM: NADH/Ubiquinone/plastoquinone (complex I) YP_001233750.1 PFAM: protein of unknown function DUF190 YP_001233751.1 PFAM: protein of unknown function DUF190 YP_001233752.1 PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase; Male sterility C-terminal domain YP_001233753.1 TIGRFAM: dTDP-4-dehydrorhamnose 3,5-epimerase; PFAM: dTDP-4-dehydrorhamnose 3,5-epimerase related YP_001233754.1 TIGRFAM: glucose-1-phosphate thymidylyltransferase; PFAM: Nucleotidyl transferase YP_001233755.1 TIGRFAM: dTDP-glucose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility C-terminal domain YP_001233756.1 PFAM: glycosyl transferase, family 2; glycosyl transferase, group 1 YP_001233757.1 PFAM: Amidase YP_001233759.1 PFAM: short-chain dehydrogenase/reductase SDR; KR YP_001233760.1 PFAM: AMP-dependent synthetase and ligase YP_001233761.1 PFAM: MmgE/PrpD family protein YP_001233762.1 catalyzes the synthesis of 2-methylcitrate from propionyl-CoA and oxaloacetate; also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity YP_001233763.1 TIGRFAM: methylisocitrate lyase YP_001233764.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain YP_001233765.1 PFAM: Enoyl-CoA hydratase/isomerase YP_001233766.1 TIGRFAM: 3-hydroxyisobutyrate dehydrogenase; PFAM: NADP oxidoreductase, coenzyme F420-dependent; 6-phosphogluconate dehydrogenase, NAD-binding YP_001233767.1 PFAM: AMP-dependent synthetase and ligase YP_001233768.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR YP_001233769.1 TIGRFAM: DNA mismatch repair protein MutL; PFAM: ATP-binding region, ATPase domain protein; DNA mismatch repair protein, C-terminal domain protein YP_001233770.1 PFAM: Alpha/beta hydrolase fold-3 domain protein YP_001233771.1 PFAM: major facilitator superfamily MFS_1 YP_001233773.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis YP_001233774.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme YP_001233778.1 PFAM: NADH ubiquinone oxidoreductase, 20 kDa subunit YP_001233779.1 PFAM: ribonuclease HII/HIII YP_001233782.1 catalyzes the formation of phenylpyruvate from prephenate in phenylalanine biosynthesis YP_001233783.1 CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS YP_001233784.1 PFAM: cytochrome c, class I YP_001233785.1 PFAM: inositol monophosphatase YP_001233786.1 PFAM: GCN5-related N-acetyltransferase YP_001233787.1 TIGRFAM: tartrate dehydrogenase; PFAM: isocitrate/isopropylmalate dehydrogenase YP_001233788.1 PFAM: amino acid permease-associated region YP_001233789.1 PFAM: lipid A biosynthesis acyltransferase YP_001233790.1 TIGRFAM: tetraacyldisaccharide 4'-kinase; PFAM: Tetraacyldisaccharide-1-P 4'-kinase YP_001233791.1 PFAM: Three-deoxy-D-manno-octulosonic-acid transferase domain protein YP_001233792.1 PFAM: protein of unknown function DUF374 YP_001233793.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001233796.1 in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall YP_001233798.1 PFAM: penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain YP_001233799.1 TIGRFAM: rod shape-determining protein RodA; PFAM: cell cycle protein YP_001233800.1 flavohemoprotein; catalyzes the formation of nitrate from nitric oxide; can also catalyze the reduction of dihydropteridine YP_001233802.1 PFAM: AMP-dependent synthetase and ligase YP_001233804.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination YP_001233805.1 TIGRFAM: 3-methyl-2-oxobutanoate hydroxymethyltransferase; PFAM: Ketopantoate hydroxymethyltransferase YP_001233806.1 PFAM: carbonic anhydrase YP_001233807.1 SMART: helix-turn-helix- domain containing protein, AraC type YP_001233808.1 PFAM: aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead; cyclase/dehydrase; aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding; carbon monoxide dehydrogenase subunit G YP_001233809.1 PFAM: molybdopterin dehydrogenase, FAD-binding YP_001233810.1 PFAM: ferredoxin; [2Fe-2S]-binding domain protein YP_001233811.1 PFAM: AMP-dependent synthetase and ligase YP_001233812.1 PFAM: Enoyl-CoA hydratase/isomerase YP_001233813.1 PFAM: OmpA/MotB domain protein YP_001233814.1 PFAM: Antibiotic biosynthesis monooxygenase YP_001233815.1 PFAM: protein of unknown function DUF1348 YP_001233816.1 PFAM: regulatory protein, TetR YP_001233817.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001233818.1 PFAM: regulatory protein GntR, HTH; aminotransferase, class I and II YP_001233819.1 PFAM: protein of unknown function DUF983 YP_001233821.1 TIGRFAM: PAS sensor protein; PFAM: chemotaxis sensory transducer; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein YP_001233822.1 leucyltransferase; phenylalanyltransferse; functions in the N-end rule pathway; transfers Leu, Phe, Met, from aminoacyl-tRNAs to N-terminal of proteins with Arg or Lys YP_001233823.1 PFAM: extracellular solute-binding protein, family 3; SMART: ionotropic glutamate receptor YP_001233824.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component YP_001233825.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001233826.1 PFAM: PfkB domain protein YP_001233830.1 PFAM: Substrate-binding region of ABC-type glycine betaine transport system YP_001233835.1 PFAM: ETC complex I subunit conserved region YP_001233836.1 PFAM: protein of unknown function DUF192 YP_001233837.1 PFAM: histone deacetylase superfamily YP_001233838.1 TIGRFAM: peptide chain release factor 3; small GTP-binding protein; PFAM: protein synthesis factor, GTP-binding; elongation factor Tu, domain 2 protein YP_001233844.1 PFAM: transposase, IS4 family protein YP_001233847.1 class I; LysRS1; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri this enzyme charges both tRNA molecules for lysine that exist in this organism (but the tRNALysUUU very poorly) and in the presence of LysRS2 can charge tRNAPyl with lysine YP_001233848.1 TIGRFAM: potassium-transporting ATPase, A subunit; PFAM: K+ transporting ATPase, A subunit YP_001233849.1 TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; K+-transporting ATPase, B subunit; PFAM: Haloacid dehalogenase domain protein hydrolase; E1-E2 ATPase-associated domain protein YP_001233850.1 TIGRFAM: potassium-transporting ATPase, C subunit; PFAM: K+ transporting ATPase, KdpC subunit YP_001233853.1 PFAM: ATP-binding region, ATPase domain protein; histidine kinase A domain protein; Osmosensitive K+ channel His kinase sensor; UspA domain protein YP_001233854.1 PFAM: response regulator receiver; transcriptional regulator domain protein YP_001233855.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001233856.1 PFAM: short-chain dehydrogenase/reductase SDR; KR YP_001233857.1 PFAM: Transketolase domain protein YP_001233858.1 PFAM: Transketolase, central region; Transketolase domain protein YP_001233859.1 TIGRFAM: TRAP dicarboxylate transporter, DctP subunit; PFAM: TRAP dicarboxylate transporter- DctP subunit YP_001233860.1 PFAM: Tripartite ATP-independent periplasmic transporter, DctQ component; TRAP C4-dicarboxylate transport system permease DctM subunit YP_001233862.1 PFAM: major facilitator superfamily MFS_1 YP_001233863.1 BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell YP_001233864.1 PFAM: glycosyl transferase, family 2 YP_001233865.1 PFAM: Fe-S metabolism associated SufE YP_001233866.1 TIGRFAM: tyrosyl-tRNA synthetase; PFAM: aminoacyl-tRNA synthetase, class Ib; RNA-binding S4 domain protein YP_001233868.1 catalyzes hydrolysis of 1,6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate; involved in murein recycling YP_001233869.1 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity YP_001233870.1 TIGRFAM: DNA protecting protein DprA; PFAM: SMF family protein YP_001233871.1 TIGRFAM: dihydroorotase, multifunctional complex type; PFAM: amidohydrolase YP_001233872.1 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis YP_001233873.1 PFAM: peptidase S24, S26A and S26B YP_001233875.1 PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase YP_001233877.1 B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE YP_001233878.1 Catalyzes the rate-limiting step in dNTP synthesis YP_001233879.1 PFAM: aminotransferase, class I and II YP_001233880.1 PFAM: ABC-2 type transporter YP_001233881.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001233883.1 TIGRFAM: diaminopimelate decarboxylase; PFAM: Orn/DAP/Arg decarboxylase 2 YP_001233884.1 catalyzes the formation of arginine from (N-L-arginino)succinate YP_001233885.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein YP_001233886.1 catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming YP_001233887.1 TIGRFAM: TonB family protein YP_001233889.1 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains YP_001233890.1 PFAM: Pyrrolo-quinoline quinone YP_001233893.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins YP_001233895.1 TIGRFAM: DNA repair protein RecN; PFAM: SMC domain protein YP_001233896.1 TIGRFAM: DNA ligase, NAD-dependent; PFAM: BRCT domain protein; zinc-finger, NAD-dependent DNA ligase C4-type; NAD-dependent DNA ligase, OB-fold; NAD-dependent DNA ligase, adenylation; SMART: NAD-dependent DNA ligase-like YP_001233897.1 TIGRFAM: RNA polymerase-binding protein DksA; PFAM: zinc finger, DksA/TraR C4-type YP_001233899.1 part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum YP_001233902.1 PFAM: glycosyl transferase, group 1 YP_001233903.1 PFAM: response regulator receiver; ATP-binding region, ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein YP_001233905.1 PFAM: peptidase S15; peptidase S9, prolyl oligopeptidase active site domain protein; dienelactone hydrolase YP_001233906.1 PFAM: conserved hypothetical protein 245 YP_001233907.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001233908.1 PFAM: peptidase M20; peptidase dimerisation domain protein YP_001233909.1 4-alpha-hydroxytetrahydrobiopterin dehydratase activity; catalyzes the formation of (6R)-6-(L-erythro-1,2-dihydroxypropyl)-7, 8-dihydro-6H-pterin from (6R)-6-(L-erythro-1,2-dihydroxypropyl)-5,6,7, 8-tetrahydro-4a-hydroxypterin; functions in recycling tetrahydrobiopterin (BH4) in phenylalanine hydroxylase reaction YP_001233915.1 PFAM: transposase, mutator type YP_001233923.1 PFAM: transposase IS66 YP_001233924.1 PFAM: IS66 Orf2 family protein YP_001233925.1 PFAM: transposase IS3/IS911 family protein YP_001233927.1 PFAM: protein of unknown function DUF262 YP_001233928.1 PFAM: transposase, mutator type YP_001233929.1 PFAM: CopG domain protein DNA-binding domain protein YP_001233931.1 PFAM: BsuBIPstI restriction endonuclease domain protein YP_001233933.1 PFAM: UvrD/REP helicase YP_001233935.1 PFAM: transposase, IS204/IS1001/IS1096/IS1165 family protein YP_001233936.1 PFAM: transposase, mutator type YP_001233943.1 PFAM: transposase, mutator type YP_001233945.1 PFAM: transposase, IS111A/IS1328/IS1533; transposase IS116/IS110/IS902 family protein YP_001233949.1 PFAM: phage integrase family protein YP_001233951.1 PFAM: Glutathione S-transferase, N-terminal domain YP_001233952.1 PFAM: Alpha/beta hydrolase fold-3 domain protein YP_001233954.1 TIGRFAM: dihydropteroate synthase; PFAM: dihydropteroate synthase, DHPS YP_001233955.1 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate YP_001233956.1 TIGRFAM: phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1 YP_001233957.1 PFAM: OsmC family protein YP_001233959.1 PFAM: Inositol phosphatase/fructose-1,6-bisphosphatase YP_001233960.1 PFAM: phosphoribulokinase/uridine kinase YP_001233961.1 TIGRFAM: ketose-bisphosphate aldolase; fructose-bisphosphate aldolase, class II, Calvin cycle subtype; PFAM: ketose-bisphosphate aldolase, class-II YP_001233962.1 type III RuBisCO; involved in carbon fixation YP_001233963.1 PFAM: ribulose bisphosphate carboxylase, small chain YP_001233964.1 PFAM: AAA ATPase, central domain protein; SMART: AAA ATPase YP_001233965.1 PFAM: ribulose-phosphate 3-epimerase YP_001233966.1 Catalyzes the deamination of cytosine to uracil and ammonia YP_001233967.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate YP_001233968.1 PFAM: short-chain dehydrogenase/reductase SDR YP_001233970.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001233971.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001233973.1 PFAM: protein of unknown function DUF1491 YP_001233974.1 PFAM: formate/nitrite transporter YP_001233976.1 TIGRFAM: formate dehydrogenase family accessory protein FdhD; PFAM: formate dehydrogenase, subunit FdhD YP_001233977.1 TIGRFAM: formate dehydrogenase, alpha subunit; PFAM: ferredoxin; 4Fe-4S ferredoxin, iron-sulfur binding domain protein; molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region YP_001233978.1 PFAM: Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit YP_001233979.1 PFAM: NADH dehydrogenase (ubiquinone), 24 kDa subunit YP_001233980.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001233981.1 PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein YP_001233982.1 TIGRFAM: FolC bifunctional protein; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase, middle domain protein YP_001233983.1 TIGRFAM: acetyl-CoA carboxylase, carboxyl transferase, beta subunit YP_001233985.1 PFAM: glutamine amidotransferase class-I; peptidase C26 YP_001233986.1 TIGRFAM: drug resistance transporter, Bcr/CflA subfamily; PFAM: major facilitator superfamily MFS_1 YP_001233987.1 PFAM: protein of unknown function DUF202 YP_001233988.1 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids YP_001233989.1 PFAM: regulatory protein, MarR YP_001233990.1 PFAM: response regulator receiver; transcriptional regulator domain protein YP_001233991.1 PFAM: ATP-binding region, ATPase domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein YP_001233992.1 PFAM: glycosyl transferase, group 1 YP_001233993.1 PFAM: protein of unknown function DUF541 YP_001233994.1 PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like YP_001233995.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain YP_001233997.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein YP_001233998.1 PFAM: GatB/Yqey domain protein YP_001233999.1 TIGRFAM: DNA primase; PFAM: zinc finger, CHC2-family protein; TOPRIM domain protein; DNA primase catalytic core, N-terminal domain; SMART: Toprim sub domain protein YP_001234000.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this is the primary sigma factor of bacteria YP_001234001.1 PFAM: GCN5-related N-acetyltransferase YP_001234002.1 PFAM: pseudouridine synthase YP_001234003.1 PFAM: glycosyl transferase, family 20 YP_001234004.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IIB; PFAM: trehalose-phosphatase YP_001234005.1 PFAM: glycosyl transferase, family 39 YP_001234006.1 PFAM: protein of unknown function DUF461 YP_001234007.1 PFAM: electron transport protein SCO1/SenC YP_001234008.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA YP_001234009.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA YP_001234010.1 TIGRFAM: glutamyl-tRNA(Gln) amidotransferase, C subunit; PFAM: Glu-tRNAGln amidotransferase, C subunit YP_001234011.1 PFAM: Holliday junction resolvase YqgF; SMART: Resolvase, RNase H domain protein fold YP_001234013.1 PFAM: glycoside hydrolase, family 24 YP_001234019.1 PFAM: phosphoesterase YP_001234020.1 PFAM: Lytic transglycosylase, catalytic YP_001234021.1 TIGRFAM: general secretion pathway protein G; PFAM: type II secretion system protein G YP_001234023.1 TIGRFAM: general secretion pathway protein D; PFAM: type II and III secretion system protein; NolW domain protein YP_001234026.1 PFAM: Fimbrial assembly family protein YP_001234030.1 PFAM: type II secretion system protein YP_001234031.1 PFAM: type II secretion system protein E; General secretory system II, protein E domain protein; SMART: AAA ATPase YP_001234032.1 PFAM: peptidase A24A, prepilin type IV; peptidase A24A domain protein YP_001234034.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug YP_001234037.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway YP_001234038.1 PFAM: dienelactone hydrolase YP_001234039.1 hydrolyzes diadenosine polyphosphate YP_001234040.1 PFAM: protein of unknown function DUF610, YibQ YP_001234041.1 TIGRFAM: carboxyl-terminal protease; PFAM: PDZ/DHR/GLGF domain protein; peptidase S41 YP_001234042.1 PFAM: peptidase M23B YP_001234043.1 catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate YP_001234044.1 TIGRFAM: hydrolase, TatD family; PFAM: TatD-related deoxyribonuclease YP_001234045.1 PFAM: beta-lactamase domain protein YP_001234046.1 PFAM: peptidase M29, aminopeptidase II YP_001234047.1 catalyzes the formation of 2-oxobutanoate from L-threonine YP_001234048.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus YP_001234049.1 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity YP_001234050.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers YP_001234051.1 This protein performs the mismatch recognition step during the DNA repair process YP_001234052.1 catalyzes the uridylylation or deuridylylation of the PII nitrogen regulatory protein YP_001234053.1 TIGRFAM: outer membrane autotransporter barrel domain; PFAM: lipolytic enzyme, G-D-S-L family; Autotransporter beta- domain protein YP_001234054.1 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer YP_001234055.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates YP_001234056.1 binds and unfolds substrates as part of the ClpXP protease YP_001234057.1 TIGRFAM: ATP-dependent protease La; PFAM: peptidase S16, lon domain protein; AAA ATPase, central domain protein; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase YP_001234058.1 PFAM: histone family protein DNA-binding protein YP_001234059.1 PFAM: NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 YP_001234060.1 The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen YP_001234061.1 TIGRFAM: NADH (or F420H2) dehydrogenase, subunit C; PFAM: NADH dehydrogenase (ubiquinone), 30 kDa subunit YP_001234062.1 Catalyzes the transfer of electrons from NADH to quinone YP_001234063.1 TIGRFAM: NADH-quinone oxidoreductase, E subunit; PFAM: NADH dehydrogenase (ubiquinone), 24 kDa subunit YP_001234064.1 part of NADH-ubiquinone oxidoreductase complex I; shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; NuoF is part of the soluble NADH dehydrogenase fragment, which represents the electron input part of NADH dehydrogenase YP_001234065.1 Catalyzes the transfer of electrons from NADH to quinone YP_001234066.1 PFAM: respiratory-chain NADH dehydrogenase, subunit 1 YP_001234067.1 Catalyzes the transfer of electrons from NADH to quinone YP_001234068.1 PFAM: NADH-ubiquinone/plastoquinone oxidoreductase, chain 6 YP_001234069.1 PFAM: NADH-ubiquinone oxidoreductase, chain 4L YP_001234070.1 TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain L; PFAM: NADH-Ubiquinone oxidoreductase (complex I), chain 5/L domain protein; NADH/Ubiquinone/plastoquinone (complex I) YP_001234071.1 TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain M; PFAM: NADH/Ubiquinone/plastoquinone (complex I) YP_001234072.1 TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain N; PFAM: NADH/Ubiquinone/plastoquinone (complex I) YP_001234073.1 TIGRFAM: biotin--acetyl-CoA-carboxylase ligase; PFAM: biotin/lipoate A/B protein ligase YP_001234074.1 type III; catalyzes the formation of (R)-4'-phosphopantothenate from (R)-pantothenate in coenzyme A biosynthesis; type III pantothenate kinases are not subject to feedback inhibition from coenzyme A and have a high Km for ATP YP_001234075.1 PFAM: beta-lactamase domain protein; RNA-metabolising metallo-beta-lactamase YP_001234076.1 PFAM: acyltransferase 3 YP_001234077.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro) YP_001234078.1 TIGRFAM: lipoprotein releasing system, transmembrane protein, LolC/E family; PFAM: protein of unknown function DUF214 YP_001234079.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001234080.1 PFAM: Alpha/beta hydrolase fold-3 domain protein YP_001234082.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001234083.1 PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase YP_001234084.1 TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III Xth; PFAM: Endonuclease/exonuclease/phosphatase YP_001234085.1 TIGRFAM: putative deoxyguanosinetriphosphate triphosphohydrolase; PFAM: metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region YP_001234086.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase YP_001234087.1 PFAM: Sporulation domain protein YP_001234088.1 PFAM: glycoside hydrolase, family 3 domain protein YP_001234089.1 PFAM: peptidase M50 YP_001234090.1 PFAM: chromosome segregation and condensation protein ScpA YP_001234091.1 TIGRFAM: segregation and condensation protein B; PFAM: chromosome segregation and condensation protein ScpB YP_001234093.1 TIGRFAM: Sec-independent protein translocase, TatC subunit; PFAM: Sec-independent periplasmic protein translocase YP_001234094.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001234095.1 PFAM: beta-lactamase domain protein YP_001234096.1 PFAM: protein of unknown function DUF395, YeeE/YedE YP_001234097.1 PFAM: protein of unknown function DUF395, YeeE/YedE YP_001234098.1 PFAM: regulatory protein, ArsR YP_001234099.1 PFAM: thiazole biosynthesis family protein YP_001234100.1 TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein YP_001234101.1 TIGRFAM: glycine oxidase ThiO; PFAM: FAD dependent oxidoreductase YP_001234102.1 required for the synthesis of the hydromethylpyrimidine moiety of thiamine YP_001234103.1 TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; PAS fold-3 domain protein YP_001234104.1 PFAM: DSBA oxidoreductase YP_001234105.1 TIGRFAM: lytic murein transglycosylase YP_001234106.1 PFAM: Rare lipoprotein A; Sporulation domain protein YP_001234107.1 PFAM: thymidylate kinase YP_001234108.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA YP_001234109.1 TIGRFAM: methionyl-tRNA synthetase; PFAM: methionyl-tRNA synthetase, class Ia YP_001234110.1 with FliG and FliN makes up the switch complex which is involved in switching the direction of the flagella rotation; Bradyrhizobium has one thick flagellum and several thin flagella; the protein in this cluster is associated with the thick flagellum YP_001234113.1 PFAM: glycosyl transferase, family 2 YP_001234114.1 PFAM: Collagen triple helix repeat YP_001234115.1 PFAM: GCN5-related N-acetyltransferase; regulatory protein, MarR; transcriptional regulator PadR family protein YP_001234116.1 PFAM: metallophosphoesterase YP_001234117.1 PFAM: inositol monophosphatase YP_001234118.1 PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase YP_001234119.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001234120.1 PFAM: extracellular solute-binding protein, family 1 YP_001234122.1 PFAM: small multidrug resistance protein YP_001234123.1 PFAM: Substrate-binding region of ABC-type glycine betaine transport system YP_001234124.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001234125.1 TIGRFAM: glycine betaine/L-proline ABC transporter, ATPase subunit; PFAM: ABC transporter related; SMART: AAA ATPase YP_001234126.1 catalyzes the formation of betaine from betaine aldehyde YP_001234127.1 TIGRFAM: choline dehydrogenase; PFAM: glucose-methanol-choline oxidoreductase; GMC oxidoreductase YP_001234128.1 TIGRFAM: sarcosine oxidase, beta subunit family; PFAM: FAD dependent oxidoreductase YP_001234129.1 PFAM: Sarcosine oxidase, delta subunit, heterotetrameric YP_001234130.1 TIGRFAM: sarcosine oxidase, alpha subunit family; PFAM: glucose-inhibited division protein A; glycine cleavage T protein (aminomethyl transferase); Glycine cleavage T-protein, C-terminal barrel YP_001234131.1 PFAM: Sarcosine oxidase, gamma subunit YP_001234132.1 TIGRFAM: L-serine dehydratase 1; PFAM: serine dehydratase alpha chain; serine dehydratase beta chain YP_001234133.1 PFAM: electron transfer flavoprotein beta-subunit YP_001234134.1 PFAM: electron transfer flavoprotein beta-subunit; electron transfer flavoprotein, alpha subunit YP_001234135.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; protein of unknown function DUF224, cysteine-rich region domain protein YP_001234136.1 PFAM: NADH:flavin oxidoreductase/NADH oxidase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; UDP-glucose/GDP-mannose dehydrogenase YP_001234137.1 PFAM: helix-turn-helix- domain containing protein, AraC type; ThiJ/PfpI domain protein YP_001234138.1 PFAM: ferredoxin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein YP_001234139.1 PFAM: Rieske [2Fe-2S] domain protein YP_001234140.1 PFAM: helix-turn-helix- domain containing protein, AraC type; ThiJ/PfpI domain protein YP_001234141.1 PFAM: sulfatase YP_001234142.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001234143.1 TIGRFAM: ubiquinone biosynthesis O-methyltransferase; PFAM: UbiE/COQ5 methyltransferase; methyltransferase small; NodS family protein; Methyltransferase type 11; Methyltransferase type 12 YP_001234144.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP, in Bacillus, lysine sensitive; regulated by response to starvation. YP_001234145.1 PFAM: 2-nitropropane dioxygenase, NPD YP_001234146.1 TIGRFAM: phosphoenolpyruvate-protein phosphotransferase; PFAM: PEP-utilizing enzyme; GAF domain protein; PEP-utilising enzyme, mobile region; PEP-utilising enzyme domain protein YP_001234148.1 catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis YP_001234149.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG YP_001234150.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2 YP_001234151.1 TIGRFAM: modification methylase, HemK family; PFAM: methyltransferase small; Methyltransferase type 11 YP_001234154.1 PFAM: CHAP domain containing protein YP_001234155.1 TIGRFAM: integral membrane protein MviN; PFAM: multi antimicrobial extrusion protein MatE; virulence factor MVIN family protein YP_001234156.1 TIGRFAM: tryptophanyl-tRNA synthetase; PFAM: aminoacyl-tRNA synthetase, class Ib YP_001234157.1 PFAM: phosphoglucomutase/phosphomannomutase C terminal; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III YP_001234158.1 TIGRFAM: UTP-glucose-1-phosphate uridylyltransferase; PFAM: Nucleotidyl transferase YP_001234159.1 PFAM: MaoC domain protein dehydratase YP_001234160.1 PFAM: alpha/beta hydrolase fold YP_001234161.1 Modulates Rho-dependent transcription termination YP_001234162.1 TIGRFAM: preprotein translocase, SecE subunit; PFAM: protein secE/sec61-gamma protein YP_001234166.1 TIGRFAM: outer membrane autotransporter barrel domain; autotransporter-associated beta strand repeat protein; PFAM: Autotransporter beta- domain protein YP_001234167.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain YP_001234168.1 PFAM: Aldose 1-epimerase YP_001234169.1 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs YP_001234173.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001234174.1 TIGRFAM: delta-1-pyrroline-5-carboxylate dehydrogenase; PFAM: aldehyde dehydrogenase; CopG domain protein DNA-binding domain protein; Proline dehydrogenase YP_001234175.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility C-terminal domain; KR YP_001234176.1 PFAM: DegT/DnrJ/EryC1/StrS aminotransferase YP_001234177.1 TIGRFAM: proline iminopeptidase; PFAM: alpha/beta hydrolase fold YP_001234178.1 TIGRFAM: TRAP transporter solute receptor, TAXI family YP_001234180.1 related to arylsulfate sulfotransferase involved in siderophore biosynthesis-like protein YP_001234181.1 TIGRFAM: dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase YP_001234182.1 PFAM: protein of unknown function DUF1228; major facilitator superfamily MFS_1 YP_001234183.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001234184.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001234185.1 PFAM: inner-membrane translocator YP_001234186.1 PFAM: inner-membrane translocator YP_001234187.1 PFAM: Extracellular ligand-binding receptor YP_001234188.1 PFAM: putative methyltransferase YP_001234189.1 catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase YP_001234190.1 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis YP_001234191.1 PFAM: GCN5-related N-acetyltransferase YP_001234192.1 PFAM: FAD dependent oxidoreductase; electron transfer flavoprotein-ubiquinone oxidoreductase YP_001234193.1 TIGRFAM: phage SPO1 DNA polymerase-related protein; PFAM: Uracil-DNA glycosylase superfamily YP_001234194.1 PFAM: Lytic transglycosylase, catalytic YP_001234195.1 PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein YP_001234196.1 PFAM: oxidoreductase domain protein; Oxidoreductase, C-terminal domain YP_001234197.1 PFAM: periplasmic binding protein/LacI transcriptional regulator YP_001234198.1 PFAM: inner-membrane translocator YP_001234199.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001234201.1 Transcriptional repressor of the nan operon that encodes proteins involved in sialic acid utilization YP_001234202.1 PFAM: ribulose bisphosphate carboxylase, large chain YP_001234203.1 PFAM: type III effector Hrp-dependent outers YP_001234206.1 PFAM: inner-membrane translocator; ABC transporter related; SMART: AAA ATPase YP_001234207.1 PFAM: inner-membrane translocator YP_001234208.1 PFAM: NADPH-dependent FMN reductase YP_001234209.1 PFAM: phosphate transporter YP_001234210.1 PFAM: MscS Mechanosensitive ion channel YP_001234211.1 PFAM: Nitrile hydratase alpha chain YP_001234214.1 PFAM: General substrate transporter; major facilitator superfamily MFS_1 YP_001234215.1 TIGRFAM: fumarylacetoacetase; PFAM: fumarylacetoacetate (FAA) hydrolase YP_001234220.1 PFAM: Alpha/beta hydrolase fold-3 domain protein YP_001234221.1 PFAM: short-chain dehydrogenase/reductase SDR; KR YP_001234223.1 PFAM: regulatory protein, TetR YP_001234224.1 Catalyzes the first step in the glyoxalate cycle, which converts lipids to carbohydrates YP_001234226.1 PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70, region 4 type 2 YP_001234229.1 PFAM: cytochrome c oxidase, subunit I YP_001234230.1 PFAM: cytochrome c oxidase, subunit II YP_001234232.1 PFAM: Bile acid:sodium symporter YP_001234233.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001234234.1 PFAM: Methyltransferase type 11; Methyltransferase type 12 YP_001234236.1 PFAM: Resolvase, N-terminal domain YP_001234237.1 PFAM: transposase Tn3 family protein YP_001234238.1 PFAM: CBS domain containing protein YP_001234239.1 TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain N; PFAM: NADH/Ubiquinone/plastoquinone (complex I) YP_001234240.1 TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain M; PFAM: NADH/Ubiquinone/plastoquinone (complex I) YP_001234241.1 TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain L; PFAM: NADH-Ubiquinone oxidoreductase (complex I), chain 5/L domain protein; NADH/Ubiquinone/plastoquinone (complex I) YP_001234242.1 PFAM: NADH-ubiquinone oxidoreductase, chain 4L YP_001234243.1 PFAM: NADH-ubiquinone/plastoquinone oxidoreductase, chain 6 YP_001234244.1 TIGRFAM: NADH-quinone oxidoreductase, chain I; PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001234245.1 Catalyzes the transfer of electrons from NADH to quinone YP_001234246.1 TIGRFAM: NADH-quinone oxidoreductase, chain G; PFAM: ferredoxin; molybdopterin oxidoreductase Fe4S4 region YP_001234247.1 PFAM: Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit YP_001234248.1 TIGRFAM: NADH-quinone oxidoreductase, E subunit; PFAM: NADH dehydrogenase (ubiquinone), 24 kDa subunit YP_001234249.1 NuoCD; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; subunits NuoCD, E, F, and G constitute the peripheral sector of the complex; in Escherichia coli this gene encodes a fusion protein of NuoC and NuoD that are found separate in other organisms YP_001234250.1 TIGRFAM: NADH-quinone oxidoreductase, B subunit; PFAM: NADH ubiquinone oxidoreductase, 20 kDa subunit YP_001234251.1 PFAM: NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 YP_001234252.1 TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: cation transporting ATPase domain protein; Haloacid dehalogenase domain protein hydrolase; cation transporting ATPase domain protein; E1-E2 ATPase-associated domain protein YP_001234253.1 PFAM: sodium/calcium exchanger membrane region YP_001234254.1 PFAM: Semialdehyde dehydrogenase, NAD - binding; oxidoreductase domain protein; Oxidoreductase, C-terminal domain; homoserine dehydrogenase, NAD-binding YP_001234255.1 PFAM: molybdopterin dehydrogenase, FAD-binding; CO dehydrogenase flavoprotein domain protein YP_001234256.1 PFAM: aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead; aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding YP_001234258.1 PFAM: protein of unknown function DUF156 YP_001234259.1 TIGRFAM: cation diffusion facilitator family transporter; PFAM: cation efflux protein YP_001234260.1 PFAM: regulatory protein, MerR YP_001234262.1 TIGRFAM: cation diffusion facilitator family transporter; PFAM: cation efflux protein YP_001234263.1 PFAM: multicopper oxidase, type 1; multicopper oxidase, type 2; multicopper oxidase, type 3 YP_001234265.1 PFAM: acyltransferase 3 YP_001234266.1 PFAM: extracellular solute-binding protein, family 3 YP_001234267.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component YP_001234268.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001234269.1 PFAM: inner-membrane translocator YP_001234270.1 PFAM: inner-membrane translocator YP_001234271.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001234273.1 TIGRFAM: 4-hydroxythreonine-4-phosphate dehydrogenase; PFAM: Pyridoxal phosphate biosynthetic protein PdxA YP_001234275.1 PFAM: regulatory protein, DeoR YP_001234276.1 PFAM: helix-turn-helix- domain containing protein, AraC type; ThiJ/PfpI domain protein YP_001234277.1 PFAM: metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region YP_001234278.1 PFAM: Catalase domain protein YP_001234279.1 PFAM: amidohydrolase; Amidohydrolase 3 YP_001234280.1 PFAM: permease for cytosine/purines, uracil, thiamine, allantoin YP_001234282.1 PFAM: protein of unknown function DUF989 YP_001234283.1 PFAM: Transthyretin YP_001234284.1 PFAM: protein of unknown function DUF182 YP_001234285.1 PFAM: aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead; aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding YP_001234286.1 PFAM: molybdopterin dehydrogenase, FAD-binding; [2Fe-2S]-binding domain protein; CO dehydrogenase flavoprotein domain protein YP_001234287.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001234288.1 catalyzes the formation of 2-hydroxy-3-oxopropanoate (tartronate semialdehyde) from two molecules of glyoxylate YP_001234289.1 PFAM: Xylose isomerase domain protein TIM barrel YP_001234290.1 TIGRFAM: 2-hydroxy-3-oxopropionate reductase; PFAM: 6-phosphogluconate dehydrogenase, NAD-binding YP_001234291.1 PFAM: MOFRL domain protein YP_001234292.1 TIGRFAM: amidase, hydantoinase/carbamoylase family; PFAM: peptidase M20; peptidase dimerisation domain protein YP_001234293.1 PFAM: peptidase M20; peptidase dimerisation domain protein YP_001234294.1 PFAM: polysaccharide deacetylase YP_001234295.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001234297.1 PFAM: Collagen triple helix repeat YP_001234301.1 PFAM: phage integrase family protein YP_001234308.1 PFAM: peptidyl-prolyl cis-trans isomerase, cyclophilin type YP_001234309.1 TIGRFAM: pantetheine-phosphate adenylyltransferase; cytidyltransferase-related domain; PFAM: cytidylyltransferase YP_001234310.1 negatively supercoils closed circular double-stranded DNA YP_001234312.1 PFAM: manganese and iron superoxide dismutase YP_001234313.1 TIGRFAM: preprotein translocase, YajC subunit; PFAM: YajC family protein YP_001234314.1 PFAM: protein of unknown function DUF815 YP_001234315.1 TIGRFAM: TonB family protein YP_001234316.1 PFAM: extracellular solute-binding protein, family 5 YP_001234317.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001234318.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001234319.1 TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter, C-terminal domain protein; SMART: AAA ATPase YP_001234320.1 PFAM: MotA/TolQ/ExbB proton channel YP_001234321.1 PFAM: Biopolymer transport protein ExbD/TolR YP_001234322.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs YP_001234323.1 PFAM: GCN5-related N-acetyltransferase YP_001234324.1 PFAM: Fmu (Sun) domain protein YP_001234325.1 TIGRFAM: inosine-5'-monophosphate dehydrogenase; PFAM: CBS domain containing protein; IMP dehydrogenase/GMP reductase YP_001234326.1 PFAM: AMP-dependent synthetase and ligase YP_001234327.1 PFAM: protein of unknown function DUF1211 YP_001234329.1 PFAM: Polyprenyl synthetase YP_001234330.1 TIGRFAM: exodeoxyribonuclease VII, small subunit; PFAM: Exonuclease VII, small subunit YP_001234331.1 PFAM: histone deacetylase superfamily YP_001234332.1 PFAM: SirA family protein YP_001234333.1 PFAM: ROK family protein YP_001234334.1 TIGRFAM: 3'(2'),5'-bisphosphate nucleotidase; PFAM: inositol monophosphatase YP_001234335.1 catalyzes the removal of N-terminal amino acids preferably leucine from various peptides YP_001234337.1 PFAM: Uncharacterized protein UPF0114 YP_001234338.1 PFAM: protein of unknown function DUF893, YccS/YhfK YP_001234339.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling YP_001234340.1 TIGRFAM: DNA repair protein RecO YP_001234342.1 TIGRFAM: amidohydrolase; PFAM: peptidase M20; peptidase dimerisation domain protein YP_001234344.1 TIGRFAM: dTDP-glucose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility C-terminal domain YP_001234345.1 TIGRFAM: glucose-1-phosphate thymidylyltransferase; PFAM: Nucleotidyl transferase YP_001234346.1 TIGRFAM: dTDP-4-dehydrorhamnose 3,5-epimerase; PFAM: dTDP-4-dehydrorhamnose 3,5-epimerase related YP_001234347.1 PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase; Male sterility C-terminal domain YP_001234348.1 PFAM: glycosyl transferase, family 2 YP_001234349.1 PFAM: ABC transporter related; SbmABacA family protein; ABC transporter domain protein; SMART: AAA ATPase YP_001234350.1 TIGRFAM: transketolase; PFAM: Transketolase domain protein; Transketolase, central region YP_001234351.1 TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: glyceraldehyde 3-phosphate dehydrogenase YP_001234352.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway YP_001234353.1 PFAM: peptidase U62, modulator of DNA gyrase YP_001234354.1 PFAM: cytochrome oxidase assembly YP_001234355.1 PFAM: cytochrome oxidase assembly YP_001234356.1 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes YP_001234357.1 PFAM: Lysine exporter protein (LYSE/YGGA) YP_001234358.1 catalyzes the formation of L-homocysteine from S-adenosyl-L-homocysteine YP_001234360.1 TIGRFAM: molybdenum cofactor synthesis domain; PFAM: molybdopterin binding domain; MoeA domain protein, domain I and II; MoeA domain protein, domain IV YP_001234361.1 TIGRFAM: molybdenum cofactor biosynthesis protein C; PFAM: molybdopterin cofactor biosynthesis MoaC region YP_001234362.1 involved in tryptophan biosynthesis; amino acid biosynthesis; converts 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate to C(1)-(3-indolyl)-glycerol 3-phosphate and carbon dioxide and water YP_001234363.1 bifunctional anthranilate synthase II/anthranilate phosphoribosyltransferase; TrpD; forms a heterotetramer with Trp E and the complex catalyzes the formation of anthranilate from chorismate and glutamine; also catalyzes the formation of N-(5-phospho-D-ribosyl)-anthranilate from athranilate and 5-phospho-alpha-D-ribose 1-diphosphate; functions in tryptophan biosynthesis YP_001234364.1 TIGRFAM: anthranilate synthase component I; PFAM: Anthranilate synthase component I and chorismate binding protein; Anthranilate synthase component I domain protein YP_001234366.1 PFAM: triosephosphate isomerase YP_001234367.1 TIGRFAM: preprotein translocase, SecG subunit; PFAM: Preprotein translocase SecG subunit YP_001234368.1 CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer YP_001234369.1 catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis YP_001234372.1 PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein YP_001234373.1 catalyzes the formation of malate from glyoxylate and acetyl-CoA YP_001234374.1 PFAM: EAL domain protein YP_001234378.1 PFAM: Polypeptide-transport-associated domain protein, ShlB-type YP_001234382.1 PFAM: membrane protein involved in aromatic hydrocarbon degradation YP_001234383.1 PFAM: glucose-methanol-choline oxidoreductase; GMC oxidoreductase YP_001234384.1 PFAM: aldehyde dehydrogenase YP_001234386.1 PFAM: AMP-dependent synthetase and ligase YP_001234387.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation YP_001234388.1 PFAM: MaoC domain protein dehydratase YP_001234389.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis YP_001234390.1 functions in fatty acid oxidation; converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA YP_001234391.1 PFAM: ferredoxin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein YP_001234392.1 PFAM: fatty acid desaturase YP_001234396.1 PFAM: protein of unknown function DUF453 YP_001234397.1 PFAM: regulatory protein GntR, HTH; GntR domain protein; Helix-turn-helix, type 11 domain protein YP_001234398.1 PFAM: MmgE/PrpD family protein YP_001234399.1 PFAM: General substrate transporter; major facilitator superfamily MFS_1 YP_001234400.1 PFAM: isocitrate/isopropylmalate dehydrogenase YP_001234401.1 PFAM: glycoside hydrolase 15-related YP_001234402.1 TIGRFAM: ribose 5-phosphate isomerase; carbohydrate kinase, thermoresistant glucokinase family; PFAM: shikimate kinase; Ribose 5-phosphate isomerase YP_001234403.1 TIGRFAM: 6-phosphogluconolactonase YP_001234404.1 TIGRFAM: Cof-like hydrolase; HAD-superfamily hydrolase, subfamily IIB; PFAM: Haloacid dehalogenase domain protein hydrolase; sucrose-6F-phosphate phosphohydrolase; Haloacid dehalogenase domain protein hydrolase, type 3 YP_001234405.1 TIGRFAM: glucose-6-phosphate 1-dehydrogenase; PFAM: glucose-6-phosphate dehydrogenase YP_001234406.1 similar to full-length Gnd, these proteins seems to have a truncated C-terminal 6PGD domainin; in Methylobacillus flagellatus this gene is essential for NAD+-dependent oxidation of 6-phosphogluconate YP_001234407.1 catalyzes the reversible formation of D-erythrose 4-phosphate and D-fructose 6-phosphate from sedoheptulose 7-phosphate and D-glyceraldehyde 3-phosphate; catalyzes isomerization of glucose 6-phosphate and fructose 6-phosphate YP_001234408.1 binds to the ribosome on the universally-conserved alpha-sarcin loop YP_001234409.1 PFAM: protein of unknown function DUF195 YP_001234412.1 PFAM: transposase, IS4 family protein YP_001234413.1 PFAM: DoxX family protein YP_001234414.1 PFAM: regulatory protein, LysR; helix-turn-helix, Fis-type; LysR, substrate-binding YP_001234415.1 PFAM: transposase IS3/IS911 family protein YP_001234418.1 TIGRFAM: PAS sensor protein; PFAM: chemotaxis sensory transducer; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001234422.1 PFAM: glycosyl transferase, family 2; General secretory system II, protein E domain protein YP_001234424.1 PFAM: glycosyl transferase, family 2 YP_001234426.1 TIGRFAM: single-stranded-DNA-specific exonuclease RecJ; PFAM: phosphoesterase, RecJ domain protein; phosphoesterase, DHHA1 YP_001234427.1 type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese YP_001234428.1 catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine YP_001234429.1 PFAM: aminotransferase, class I and II YP_001234431.1 TIGRFAM: poly(R)-hydroxyalkanoic acid synthase, class I; PFAM: alpha/beta hydrolase fold; Poly-beta-hydroxybutyrate polymerase domain protein YP_001234432.1 PFAM: glycosyl transferase, group 1 YP_001234434.1 PFAM: cobalamin synthesis protein, P47K; cobalamin synthesis CobW domain protein YP_001234435.1 SMART: WD-40 repeat protein YP_001234436.1 PFAM: aldo/keto reductase YP_001234437.1 TIGRFAM: small GTP-binding protein; GTP-binding protein TypA; PFAM: elongation factor G domain protein; protein synthesis factor, GTP-binding; elongation factor Tu, domain 2 protein YP_001234439.1 PFAM: major facilitator superfamily MFS_1 YP_001234440.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001234441.1 PFAM: nucleoside diphosphate kinase YP_001234443.1 TIGRFAM: cell shape determining protein, MreB/Mrl family; PFAM: cell division protein FtsA; cell shape determining protein MreB/Mrl YP_001234444.1 PFAM: UspA domain protein YP_001234445.1 PFAM: regulatory protein, MarR YP_001234446.1 PFAM: Pirin domain protein YP_001234447.1 TIGRFAM: protease Do; PFAM: peptidase S1 and S6, chymotrypsin/Hap; PDZ/DHR/GLGF domain protein YP_001234448.1 with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP YP_001234449.1 TIGRFAM: sulfate adenylyltransferase, large subunit; PFAM: protein synthesis factor, GTP-binding; adenylylsulfate kinase; elongation factor Tu, domain 2 protein YP_001234450.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis YP_001234452.1 PFAM: Extracellular ligand-binding receptor YP_001234453.1 PFAM: protein of unknown function DUF336 YP_001234454.1 PFAM: peptidase S1 and S6, chymotrypsin/Hap; PDZ/DHR/GLGF domain protein YP_001234455.1 PFAM: glutamyl-tRNA synthetase, class Ic YP_001234456.1 PFAM: phospholipase/Carboxylesterase YP_001234457.1 PFAM: HNH endonuclease; SMART: HNH nuclease YP_001234458.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate YP_001234459.1 catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis YP_001234460.1 TIGRFAM: phosphoribosylamine--glycine ligase; PFAM: phosphoribosylglycinamide synthetase YP_001234461.1 TIGRFAM: exodeoxyribonuclease VII, large subunit; PFAM: Exonuclease VII, large subunit; nucleic acid binding, OB-fold, tRNA/helicase-type YP_001234463.1 PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70, region 4 type 2 YP_001234464.1 PFAM: ferric-uptake regulator YP_001234466.1 PFAM: protein of unknown function DUF1321 YP_001234467.1 TIGRFAM: hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit; hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit; PFAM: Fe-S type hydro-lyase tartrate/fumarate alpha region; Fe-S type hydro-lyase tartrate/fumarate beta region YP_001234468.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase YP_001234469.1 Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step YP_001234470.1 TIGRFAM: tRNA-guanine transglycosylase, various specificities; queuine tRNA-ribosyltransferase; PFAM: Queuine/other tRNA-ribosyltransferase YP_001234471.1 NADPH-dependent; catalyzes the reduction of 7-cyano-7-deazaguanine to 7-aminomethyl-7-deazaguanine in queuosine biosynthesis YP_001234472.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; domain of unknown function DUF1730 YP_001234473.1 TIGRFAM: large conductance mechanosensitive channel protein; PFAM: large-conductance mechanosensitive channel YP_001234475.1 PFAM: LrgB family protein YP_001234476.1 PFAM: LrgA family protein YP_001234477.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001234478.1 PFAM: UDP-glucose/GDP-mannose dehydrogenase; 3-hydroxyacyl-CoA dehydrogenase, NAD-binding YP_001234479.1 PFAM: Methyltransferase type 11; Methyltransferase type 12 YP_001234480.1 PFAM: Tetratricopeptide TPR_4; Methyltransferase type 11; Methyltransferase type 12 YP_001234482.1 PFAM: phospholipid/glycerol acyltransferase YP_001234483.1 TIGRFAM: RNA modification enzyme, MiaB family; tRNA-i(6)A37 thiotransferase enzyme MiaB; PFAM: deoxyribonuclease/rho motif-related TRAM; Radical SAM domain protein; Protein of unknown function UPF0004-like; SMART: Elongator protein 3/MiaB/NifB YP_001234484.1 PFAM: PhoH family protein; KH, type 1, domain protein YP_001234485.1 PFAM: protein of unknown function UPF0054 YP_001234486.1 PFAM: CBS domain containing protein; transporter-associated region YP_001234489.1 PFAM: protein of unknown function DUF1330 YP_001234492.1 PFAM: ABC transporter, transmembrane region; ABC transporter related; SMART: AAA ATPase YP_001234493.1 PFAM: glycosyl transferase, group 1 YP_001234494.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001234495.1 PFAM: inner-membrane translocator YP_001234496.1 PFAM: periplasmic binding protein/LacI transcriptional regulator YP_001234497.1 PFAM: helix-turn-helix- domain containing protein, AraC type; HhH-GPD family protein; Ada, metal-binding domain protein; AlkA domain protein YP_001234498.1 TIGRFAM: methylated-DNA--protein-cysteine methyltransferase; PFAM: methylated-DNA-[protein]-cysteine S-methyltransferase YP_001234499.1 PFAM: aminotransferase, class V; aromatic amino acid beta-eliminating lyase/threonine aldolase YP_001234505.1 PFAM: sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; GAF domain protein; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase YP_001234506.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is not essential for growth YP_001234507.1 PFAM: amidohydrolase 2 YP_001234508.1 PFAM: monooxygenase component MmoB/DmpM YP_001234509.1 PFAM: methane/phenol/toluene hydroxylase YP_001234510.1 PFAM: ferredoxin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein YP_001234511.1 PFAM: methane/phenol/toluene hydroxylase YP_001234516.1 related to arylsulfate sulfotransferase involved in siderophore biosynthesis-like protein YP_001234517.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase YP_001234519.1 PFAM: Thioredoxin domain YP_001234520.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase YP_001234521.1 PFAM: Rhodanese domain protein YP_001234522.1 TIGRFAM: efflux transporter, RND family, MFP subunit YP_001234523.1 PFAM: acriflavin resistance protein YP_001234524.1 PFAM: helix-turn-helix domain protein YP_001234525.1 PFAM: NADH/Ubiquinone/plastoquinone (complex I) YP_001234528.1 PFAM: NADH/Ubiquinone/plastoquinone (complex I) YP_001234529.1 PFAM: NADH-ubiquinone oxidoreductase, chain 49kDa YP_001234530.1 PFAM: NADH ubiquinone oxidoreductase, 20 kDa subunit YP_001234531.1 PFAM: Ferritin, Dps family protein YP_001234532.1 PFAM: tRNA/rRNA methyltransferase (SpoU) YP_001234533.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA YP_001234534.1 PFAM: natural resistance-associated macrophage protein YP_001234535.1 catalyzes the formation of L-ornithine from N(2)-acetyl-L-ornithine YP_001234536.1 catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia YP_001234538.1 heat shock protein involved in degradation of misfolded proteins YP_001234539.1 heat shock protein involved in degradation of misfolded proteins YP_001234541.1 PFAM: General substrate transporter; major facilitator superfamily MFS_1 YP_001234542.1 PFAM: imidazoleglycerol-phosphate dehydratase YP_001234543.1 with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide YP_001234544.1 PFAM: GCN5-related N-acetyltransferase YP_001234545.1 catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide YP_001234546.1 catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase YP_001234547.1 catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribolsyl)-ATP in histidine biosynthesis YP_001234548.1 TIGRFAM: N-acetylglucosamine-6-phosphate deacetylase; PFAM: amidohydrolase YP_001234549.1 PFAM: iron-containing alcohol dehydrogenase YP_001234550.1 PFAM: beta-lactamase domain protein YP_001234551.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR YP_001234552.1 PFAM: Acetamidase/Formamidase YP_001234553.1 PFAM: short-chain dehydrogenase/reductase SDR; KR YP_001234554.1 PFAM: short-chain dehydrogenase/reductase SDR YP_001234555.1 PFAM: AMP-dependent synthetase and ligase YP_001234556.1 PFAM: NAD-glutamate dehydrogenase YP_001234557.1 TIGRFAM: ATP-dependent metalloprotease FtsH; PFAM: peptidase M41; AAA ATPase, central domain protein; peptidase M41, FtsH extracellular; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase YP_001234558.1 PFAM: Endonuclease/exonuclease/phosphatase YP_001234559.1 PFAM: phospholipase D/Transphosphatidylase YP_001234561.1 PFAM: Polyprenyl synthetase YP_001234564.1 PFAM: acetyl-CoA hydrolase/transferase YP_001234565.1 binds the polymerase to DNA and acts as a sliding clamp YP_001234566.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001234567.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001234568.1 PFAM: fumarate lyase YP_001234569.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001234570.1 PFAM: DoxX family protein YP_001234571.1 PFAM: Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B YP_001234572.1 PFAM: major facilitator superfamily MFS_1 YP_001234573.1 PFAM: Na+/solute symporter YP_001234575.1 PFAM: guanylate kinase; SMART: guanylate kinase/L-type calcium channel region YP_001234576.1 PFAM: YicC N-terminal domain protein; domain of unknown function DUF1732 YP_001234577.1 PFAM: DNA methylase N-4/N-6 domain protein YP_001234578.1 PFAM: Enoyl-CoA hydratase/isomerase YP_001234579.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase YP_001234580.1 PFAM: protein of unknown function UPF0079 YP_001234582.1 TIGRFAM: UvrD-like DNA helicase, C terminal; PFAM: UvrD/REP helicase YP_001234583.1 TIGRFAM: thioredoxin; PFAM: Thioredoxin domain YP_001234584.1 PFAM: thioesterase superfamily protein YP_001234585.1 PFAM: General substrate transporter; major facilitator superfamily MFS_1 YP_001234586.1 PFAM: aldo/keto reductase YP_001234587.1 PFAM: MotA/TolQ/ExbB proton channel YP_001234588.1 PFAM: Biopolymer transport protein ExbD/TolR YP_001234589.1 PFAM: FAD linked oxidase domain protein YP_001234590.1 PFAM: metallophosphoesterase YP_001234591.1 PFAM: cytochrome B561 YP_001234593.1 PFAM: Negative transcriptional regulator YP_001234594.1 PFAM: shikimate kinase; 3-dehydroquinate synthase YP_001234595.1 PFAM: phage integrase family protein; phage integrase domain protein SAM domain protein YP_001234596.1 PFAM: Cobyrinic acid a,c-diamide synthase YP_001234597.1 PFAM: GTP-binding signal recognition particle SRP54, G- domain YP_001234598.1 membrane protein involved in the flagellar export apparatus YP_001234599.1 PFAM: response regulator receiver; sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; SMART: AAA ATPase YP_001234600.1 TIGRFAM: flagellar motor switch protein FliN; PFAM: surface presentation of antigens (SPOA) protein YP_001234601.1 One of three proteins involved in switching the direction of the flagellar rotation YP_001234602.1 TIGRFAM: flagellar M-ring protein FliF; PFAM: secretory protein YscJ/FliF family protein; Flagellar M-ring C-terminal domain protein YP_001234603.1 PFAM: CMP/dCMP deaminase, zinc-binding YP_001234604.1 PFAM: glutamine amidotransferase class-I; peptidase C26 YP_001234605.1 PFAM: RNA-binding S4 domain protein; pseudouridine synthase YP_001234606.1 TIGRFAM: putative methyltransferase; PFAM: conserved hypothetical protein 95 YP_001234608.1 PFAM: ABC-1 domain protein YP_001234609.1 TIGRFAM: oligoendopeptidase, pepF/M3 family; PFAM: peptidase M3A and M3B, thimet/oligopeptidase F; Oligopeptidase F YP_001234610.1 PFAM: protein of unknown function DUF519 YP_001234611.1 PFAM: NADP oxidoreductase, coenzyme F420-dependent; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein YP_001234612.1 TIGRFAM: haloacid dehalogenase, type II; HAD-superfamily hydrolase, subfamily IA, variant 2 (HAD-like); PFAM: Haloacid dehalogenase domain protein hydrolase YP_001234614.1 PFAM: MscS Mechanosensitive ion channel YP_001234616.1 CysK; forms a complex with serine acetyltransferase CysE; functions in cysteine biosynthesis YP_001234617.1 SMART: Rhodanese domain protein YP_001234618.1 PFAM: major facilitator superfamily MFS_1 YP_001234619.1 TIGRFAM: methionine aminopeptidase, type I; PFAM: peptidase M24 YP_001234620.1 PFAM: DNA repair protein RadC YP_001234621.1 PFAM: Methyltransferase type 11; Methyltransferase type 12 YP_001234622.1 PFAM: phosphoribosyltransferase YP_001234623.1 TIGRFAM: glutaredoxin 3; PFAM: glutaredoxin YP_001234624.1 PFAM: protein of unknown function DUF1178 YP_001234627.1 PFAM: helix-turn-helix domain protein; protein of unknown function DUF955 YP_001234628.1 TIGRFAM: isocitrate lyase; PFAM: isocitrate lyase and phosphorylmutase YP_001234629.1 PFAM: helix-hairpin-helix motif; HhH-GPD family protein YP_001234631.1 TIGRFAM: DNA polymerase I; PFAM: DNA-directed DNA polymerase; 5'-3' exonuclease; 3'-5' exonuclease; SMART: Helix-hairpin-helix domain protein, class 2 YP_001234634.1 Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis YP_001234635.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active YP_001234636.1 PFAM: Cyclopropane-fatty-acyl-phospholipid synthase; Methyltransferase type 11; Methyltransferase type 12 YP_001234637.1 PFAM: ribosomal protein L9 YP_001234638.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit YP_001234639.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21 YP_001234640.1 PFAM: Antibiotic biosynthesis monooxygenase YP_001234641.1 PFAM: biotin/lipoyl attachment domain-containing protein; phosphoribosylglycinamide synthetase; ATP-dependent carboxylate-amine ligase domain protein, ATP-grasp; Carbamoyl-phosphate synthase L chain, ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein YP_001234642.1 PFAM: Enoyl-CoA hydratase/isomerase YP_001234643.1 PFAM: carboxyl transferase YP_001234644.1 PFAM: glycosyl transferase WecB/TagA/CpsF YP_001234646.1 PFAM: glycosyl transferase, family 2 YP_001234647.1 PFAM: acyltransferase 3 YP_001234650.1 PFAM: lipopolysaccharide biosynthesis protein YP_001234651.1 PFAM: polysaccharide export protein YP_001234652.1 TIGRFAM: malonyl CoA-acyl carrier protein transacylase; PFAM: acyl transferase domain protein YP_001234653.1 TIGRFAM: 3-oxoacyl-(acyl-carrier-protein) reductase; PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR YP_001234654.1 carries the fatty acid chain in fatty acid biosynthesis YP_001234655.1 FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP YP_001234656.1 PFAM: aminodeoxychorismate lyase YP_001234657.1 TIGRFAM: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase YP_001234658.1 dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica. YP_001234660.1 PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase YP_001234662.1 PFAM: ATP-binding region, ATPase domain protein; histidine kinase A domain protein YP_001234663.1 TIGRFAM: cation diffusion facilitator family transporter; PFAM: cation efflux protein YP_001234664.1 TIGRFAM: ATP--cobalamin adenosyltransferase; PFAM: cobalamin adenosyltransferase YP_001234666.1 PFAM: short-chain dehydrogenase/reductase SDR YP_001234668.1 TIGRFAM: quinolinate synthetase complex, A subunit; PFAM: Quinolinate synthetase A YP_001234669.1 PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD-dependent pyridine nucleotide-disulphide oxidoreductase YP_001234670.1 catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide YP_001234673.1 PFAM: molybdopterin binding domain YP_001234674.1 PFAM: NUDIX hydrolase; GCN5-related N-acetyltransferase YP_001234675.1 Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway YP_001234676.1 PFAM: protein of unknown function DUF163 YP_001234677.1 TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001234678.1 TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein YP_001234681.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain YP_001234682.1 PFAM: regulatory protein GntR, HTH; GntR domain protein YP_001234683.1 PFAM: Phytanoyl-CoA dioxygenase YP_001234684.1 PFAM: oxidoreductase domain protein; SAF domain YP_001234685.1 TIGRFAM: oxygen-independent coproporphyrinogen III oxidase; PFAM: Radical SAM domain protein; HemN domain protein; SMART: Elongator protein 3/MiaB/NifB YP_001234686.1 PFAM: aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead; aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding YP_001234687.1 PFAM: DinB family protein YP_001234692.1 TIGRFAM: methyltransferase FkbM family YP_001234693.1 PFAM: short-chain dehydrogenase/reductase SDR YP_001234694.1 PFAM: cytochrome c, class I YP_001234695.1 PFAM: Pyrrolo-quinoline quinone YP_001234697.1 PFAM: acyltransferase 3 YP_001234698.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain YP_001234699.1 PFAM: regulatory protein, TetR YP_001234700.1 PFAM: short-chain dehydrogenase/reductase SDR; KR YP_001234701.1 TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase YP_001234702.1 PFAM: MaoC domain protein dehydratase YP_001234703.1 PFAM: aldo/keto reductase YP_001234705.1 PFAM: cyclic nucleotide-binding; SMART: regulatory protein, Crp YP_001234706.1 TIGRFAM: nitrate reductase, alpha subunit; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region YP_001234707.1 TIGRFAM: nitrate reductase, beta subunit; PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001234708.1 TIGRFAM: nitrate reductase molybdenum cofactor assembly chaperone; PFAM: Nitrate reductase, delta subunit YP_001234709.1 TIGRFAM: respiratory nitrate reductase, gamma subunit; PFAM: Nitrate reductase, gamma subunit YP_001234710.1 PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase YP_001234711.1 PFAM: major facilitator superfamily MFS_1 YP_001234713.1 TIGRFAM: PAS sensor protein; PFAM: chemotaxis sensory transducer; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001234714.1 PFAM: regulatory protein, LacI; periplasmic binding protein/LacI transcriptional regulator YP_001234715.1 PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein YP_001234716.1 PFAM: short-chain dehydrogenase/reductase SDR; KR YP_001234717.1 PFAM: NADP oxidoreductase, coenzyme F420-dependent; 6-phosphogluconate dehydrogenase, NAD-binding YP_001234718.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001234719.1 PFAM: inner-membrane translocator YP_001234722.1 PFAM: Carbohydrate-selective porin OprB YP_001234723.1 PFAM: General substrate transporter; major facilitator superfamily MFS_1 YP_001234724.1 PFAM: metallophosphoesterase YP_001234725.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001234727.1 PFAM: inner-membrane translocator YP_001234729.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein YP_001234730.1 TIGRFAM: molybdenum cofactor biosynthesis protein A; PFAM: Radical SAM domain protein; molybdenum cofactor synthesis domain protein; SMART: Elongator protein 3/MiaB/NifB YP_001234731.1 PFAM: protein of unknown function DUF1013 YP_001234732.1 PFAM: protein of unknown function DUF465 YP_001234733.1 PFAM: protein of unknown function DUF465 YP_001234734.1 TIGRFAM: phosphoribosylaminoimidazole carboxylase, catalytic subunit; PFAM: 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase YP_001234735.1 With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway YP_001234736.1 PFAM: ATP dependent DNA ligase domain protein; ATP dependent DNA ligase YP_001234738.1 PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; DEAD/H associated domain protein; SMART: DEAD-like helicases-like YP_001234740.1 PFAM: DNA photolyase, FAD-binding; DNA photolyase domain protein YP_001234741.1 PFAM: amine oxidase; FAD dependent oxidoreductase YP_001234742.1 PFAM: protein of unknown function DUF1365 YP_001234743.1 PFAM: Cyclopropane-fatty-acyl-phospholipid synthase; Methyltransferase type 11; Methyltransferase type 12 YP_001234745.1 PFAM: metallophosphoesterase YP_001234746.1 TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; pyridine nucleotide-disulphide oxidoreductase dimerisation region; HI0933 family protein; FAD dependent oxidoreductase YP_001234747.1 TIGRFAM: 2-oxoglutarate dehydrogenase, E2 subunit, dihydrolipoamide succinyltransferase; PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein YP_001234748.1 TIGRFAM: 2-oxoglutarate dehydrogenase, E1 subunit; PFAM: dehydrogenase, E1 component; Transketolase, central region YP_001234749.1 TIGRFAM: succinyl-CoA synthetase, alpha subunit; PFAM: CoA-binding domain protein; ATP-citrate lyase/succinyl-CoA ligase YP_001234750.1 TIGRFAM: succinyl-CoA synthetase, beta subunit; PFAM: ATP-citrate lyase/succinyl-CoA ligase; ATP-grasp domain protein YP_001234751.1 PFAM: AFG1-family ATPase YP_001234753.1 PFAM: gamma-glutamyltranspeptidase YP_001234754.1 PFAM: aminotransferase, class I and II YP_001234755.1 PFAM: CBS domain containing protein; transport-associated; SMART: Transport-associated and nodulation region, bacteria YP_001234756.1 PFAM: cyclic nucleotide-binding; regulatory protein, Crp YP_001234759.1 TIGRFAM: cytochrome d ubiquinol oxidase, subunit II; PFAM: cytochrome bd ubiquinol oxidase, subunit II YP_001234760.1 PFAM: cytochrome bd ubiquinol oxidase, subunit I YP_001234761.1 TIGRFAM: Beta tubulin, autoregulation binding site; PFAM: ABC transporter related; SMART: AAA ATPase YP_001234762.1 TIGRFAM: ABC transporter, transmembrane region, type 1; PFAM: ABC transporter, transmembrane region; ABC transporter related; SMART: AAA ATPase YP_001234763.1 PFAM: Cl- channel, voltage-gated family protein YP_001234764.1 PFAM: OsmC family protein YP_001234766.1 PFAM: short-chain dehydrogenase/reductase SDR; KR YP_001234767.1 PFAM: L-carnitine dehydratase/bile acid-inducible protein F YP_001234768.1 TIGRFAM: TonB family protein; PFAM: Gram-negative tonB protein YP_001234769.1 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion YP_001234770.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria YP_001234771.1 PFAM: GrpE protein YP_001234773.1 PFAM: short-chain dehydrogenase/reductase SDR; KR YP_001234776.1 catalyzes the formation of O-phospho-L-homoserine from L-homoserine YP_001234777.1 An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids YP_001234778.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR YP_001234779.1 PFAM: ABC transporter related; TOBE domain protein; Transport-associated OB domain protein; SMART: AAA ATPase YP_001234780.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001234781.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001234782.1 PFAM: extracellular solute-binding protein, family 1 YP_001234783.1 PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein YP_001234784.1 PFAM: carbohydrate kinase, FGGY YP_001234785.1 PFAM: putative sugar-binding domain protein YP_001234786.1 PFAM: MaoC domain protein dehydratase YP_001234787.1 Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons YP_001234788.1 TIGRFAM: ribonuclease PH; PFAM: 3' exoribonuclease YP_001234789.1 TIGRFAM: non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; PFAM: Ham1 family protein YP_001234790.1 PFAM: glutamine amidotransferase, class-II; glutamate synthase, alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase YP_001234791.1 function undetermined; similar to glutamate synthase beta subunit and related oxidoreductases which transfer electrons from NADPH to an acceptor protein or protein domain YP_001234792.1 PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase; NmrA family protein; Male sterility C-terminal domain YP_001234793.1 PFAM: 3'-5' exonuclease YP_001234794.1 TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS) YP_001234795.1 PFAM: protein of unknown function DUF1239 YP_001234796.1 PFAM: OstA family protein YP_001234797.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001234798.1 the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response YP_001234799.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation YP_001234800.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1 YP_001234801.1 binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity YP_001234802.1 TIGRFAM: ATP synthase F1, delta subunit; PFAM: H+-transporting two-sector ATPase, delta (OSCP) subunit YP_001234803.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit YP_001234804.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit YP_001234805.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit YP_001234806.1 TIGRFAM: ATP synthase F1, epsilon subunit; PFAM: H+-transporting two-sector ATPase, delta/epsilon subunit YP_001234807.1 PFAM: Malonyl-CoA decarboxylase YP_001234808.1 PFAM: General substrate transporter; major facilitator superfamily MFS_1 YP_001234809.1 TIGRFAM: squalene/oxidosqualene cyclase; squalene-hopene cyclase; PFAM: Prenyltransferase/squalene oxidase YP_001234810.1 TIGRFAM: peptide chain release factor 2; PFAM: Class I peptide chain release factor; PCRF domain protein YP_001234811.1 TIGRFAM: penicillin-binding protein, 1A family; PFAM: glycosyl transferase, family 51; penicillin-binding protein, transpeptidase YP_001234812.1 TIGRFAM: methyltransferase FkbM family YP_001234813.1 PFAM: HpcH/HpaI aldolase YP_001234814.1 TIGRFAM: TRAP dicarboxylate transporter, DctP subunit; PFAM: TRAP dicarboxylate transporter- DctP subunit YP_001234815.1 TIGRFAM: TRAP dicarboxylate transporter, DctM subunit; PFAM: Tripartite ATP-independent periplasmic transporter, DctQ component; TRAP C4-dicarboxylate transport system permease DctM subunit YP_001234816.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR YP_001234817.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III YP_001234818.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit YP_001234819.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu YP_001234820.1 TIGRFAM: PAS sensor protein; PFAM: chemotaxis sensory transducer; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001234821.1 PFAM: glutathione-dependent formaldehyde-activating, GFA YP_001234823.1 TIGRFAM: methionine synthase; PFAM: dihydropteroate synthase, DHPS; homocysteine S-methyltransferase; Methionine synthase, B12-binding module, cap domain protein; Vitamin B12 dependent methionine synthase, activation region; cobalamin B12-binding domain protein YP_001234824.1 PFAM: protein of unknown function DUF6, transmembrane YP_001234825.1 PFAM: protein of unknown function DUF81 YP_001234829.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA YP_001234830.1 PFAM: inositol monophosphatase YP_001234833.1 PFAM: OmpA/MotB domain protein YP_001234834.1 TIGRFAM: cobalt chelatase, pCobT subunit; PFAM: Cobalt chelatase, CobT subunit YP_001234835.1 TIGRFAM: cobalt chelatase, pCobS small subunit; PFAM: ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase YP_001234836.1 PFAM: heat shock protein DnaJ domain protein YP_001234837.1 PFAM: major facilitator superfamily MFS_1 YP_001234838.1 PFAM: Enoyl-CoA hydratase/isomerase YP_001234839.1 PFAM: peptidase T2, asparaginase 2 YP_001234840.1 catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde YP_001234841.1 TIGRFAM: molybdopterin-guanine dinucleotide biosynthesis protein A YP_001234842.1 PFAM: multiple antibiotic resistance (MarC)-related protein YP_001234843.1 TIGRFAM: integration host factor, beta subunit; PFAM: histone family protein DNA-binding protein YP_001234844.1 TIGRFAM: orotidine 5'-phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase YP_001234845.1 PFAM: N-(5'phosphoribosyl)anthranilate isomerase (PRAI) YP_001234846.1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases YP_001234847.1 TIGRFAM: ubiquinone/menaquinone biosynthesis methyltransferase; PFAM: UbiE/COQ5 methyltransferase; Methyltransferase type 11; Methyltransferase type 12 YP_001234848.1 TIGRFAM: phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; PFAM: flavoprotein; DNA/pantothenate metabolism flavoprotein domain protein YP_001234849.1 catalyzes the formation of dUMP from dUTP YP_001234850.1 PFAM: short-chain dehydrogenase/reductase SDR; KR YP_001234851.1 PFAM: deoxyribodipyrimidine photolyase-related protein YP_001234853.1 PFAM: Phosphoglycerate mutase YP_001234854.1 TIGRFAM: citrate synthase I; PFAM: Citrate synthase YP_001234855.1 PFAM: regulatory protein, ArsR YP_001234856.1 PFAM: NADH:flavin oxidoreductase/NADH oxidase YP_001234857.1 PFAM: short-chain dehydrogenase/reductase SDR YP_001234858.1 PFAM: protein of unknown function DUF1555 YP_001234861.1 PFAM: regulatory protein, LuxR YP_001234862.1 PFAM: cytochrome c, class I YP_001234864.1 PFAM: Pyrrolo-quinoline quinone YP_001234865.1 PFAM: protein of unknown function DUF779 YP_001234866.1 PFAM: aldehyde dehydrogenase YP_001234867.1 PFAM: sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; GAF domain protein; SMART: AAA ATPase YP_001234868.1 catalyzes the deimination of N-formimino-L-glutamate to ammonia and N-formyl-L-glutamate YP_001234869.1 TIGRFAM: imidazolonepropionase; PFAM: amidohydrolase; Amidohydrolase 3 YP_001234870.1 catalyzes the degradation of histidine to urocanate and ammmonia YP_001234871.1 PFAM: N-formylglutamate amidohydrolase YP_001234872.1 catalyzes the formation of 4-imidazolone-5-propanoate from urocanate during histidine metabolism YP_001234873.1 TIGRFAM: histidine utilization repressor; PFAM: regulatory protein GntR, HTH; UbiC transcription regulator-associated domain protein YP_001234874.1 PFAM: N-formylglutamate amidohydrolase YP_001234875.1 PFAM: protein of unknown function DUF74 YP_001234877.1 TIGRFAM: transcription-repair coupling factor; PFAM: helicase domain protein; transcription factor CarD; TRCF domain protein; type III restriction enzyme, res subunit; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like YP_001234878.1 PFAM: helicase domain protein; nucleic acid binding, OB-fold, tRNA/helicase-type; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like YP_001234879.1 PFAM: NUDIX hydrolase YP_001234880.1 in Escherichia coli this periplasmic enzyme was found to encode the periplasmic catalytic subunit of an oxidoreductase; sulfite oxidase activity not demonstrated; requires inner membrane anchor protein YedZ YP_001234881.1 functions in degradation of stringent response intracellular messenger ppGpp; in Escherichia coli this gene is co-transcribed with the toxin/antitoxin genes mazEF; activity of MazG is inhibited by MazEF in vitro; ppGpp inhibits mazEF expression; MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation; MazG also interacts with the GTPase protein Era YP_001234882.1 PFAM: inositol monophosphatase YP_001234883.1 PFAM: GTP-binding protein, HSR1-related YP_001234884.1 TIGRFAM: RNA chaperone Hfq; PFAM: Like-Sm ribonucleoprotein, core YP_001234886.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs YP_001234887.1 PFAM: ferredoxin YP_001234888.1 PFAM: aminotransferase, class V YP_001234889.1 TIGRFAM: serine O-acetyltransferase YP_001234891.1 PFAM: regulatory protein, DeoR; Helix-turn-helix, type 11 domain protein YP_001234892.1 PFAM: ROSMUCR transcriptional regulator YP_001234893.1 PFAM: SirA family protein YP_001234894.1 TIGRFAM: ribosomal-protein-alanine acetyltransferase; PFAM: GCN5-related N-acetyltransferase YP_001234895.1 PFAM: peptidase M22, glycoprotease YP_001234896.1 PFAM: nitroreductase YP_001234897.1 PFAM: nitrogen-fixing NifU domain protein YP_001234899.1 PFAM: Methyltransferase type 11 YP_001234900.1 PFAM: beta-lactamase domain protein YP_001234901.1 PFAM: AMP-dependent synthetase and ligase YP_001234902.1 PFAM: protein-L-isoaspartate(D-aspartate) O-methyltransferase YP_001234903.1 TIGRFAM: type I secretion outer membrane protein, TolC family; PFAM: outer membrane efflux protein YP_001234905.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain YP_001234906.1 PFAM: band 7 protein YP_001234907.1 PFAM: peptidase U62, modulator of DNA gyrase YP_001234908.1 PFAM: peptidase M16 domain protein YP_001234909.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine YP_001234910.1 molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA YP_001234911.1 catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis YP_001234912.1 TIGRFAM: 2'-5' RNA ligase; PFAM: 2',5' RNA ligase YP_001234913.1 TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: aldehyde dehydrogenase YP_001234914.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001234916.1 PFAM: secretion protein HlyD family protein YP_001234917.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001234918.1 PFAM: ABC-2 type transporter YP_001234919.1 PFAM: ABC-2 type transporter YP_001234920.1 catalyzes the reduction of hydroxylamine to ammonia and water YP_001234921.1 PFAM: ferredoxin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein YP_001234922.1 TIGRFAM: putative transcriptional regulator, Rrf2 family; PFAM: protein of unknown function UPF0074 YP_001234925.1 PFAM: glycosyl transferase, group 1 YP_001234927.1 PFAM: glycosyl transferase, group 1 YP_001234929.1 TIGRFAM: CRISPR-associated protein Cas1 YP_001234930.1 TIGRFAM: CRISPR-associated protein, Cse3 family; PFAM: CRISPR-associated protein, CT1974 YP_001234931.1 TIGRFAM: CRISPR-associated protein Cas5 family; CRISPR-associated protein Cas5 YP_001234932.1 TIGRFAM: CRISPR-associated protein, Cse4 family YP_001234934.1 TIGRFAM: CRISPR-associated protein, Cse1 family YP_001234935.1 TIGRFAM: CRISPR-associated helicase Cas3; PFAM: helicase domain protein YP_001234937.1 PFAM: peptidase M41; AAA ATPase, central domain protein; SMART: AAA ATPase YP_001234942.1 PFAM: NIPSNAP family containing protein YP_001234943.1 PFAM: Resolvase, N-terminal domain; Recombinase YP_001234944.1 PFAM: AAA ATPase, central domain protein; Clp N terminal domain protein; ATPase associated with various cellular activities, AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase YP_001234945.1 PFAM: MOSC domain containing protein YP_001234946.1 TIGRFAM: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase YP_001234947.1 TIGRFAM: molybdopterin-guanine dinucleotide biosynthesis protein B; PFAM: molybdopterin-guanine dinucleotide biosynthesis MobB region YP_001234949.1 TIGRFAM: molybdopterin converting factor, subunit 1; PFAM: thiamineS protein YP_001234950.1 PFAM: molybdopterin biosynthesis MoaE protein YP_001234951.1 PFAM: response regulator receiver; transcriptional regulator domain protein YP_001234952.1 PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB YP_001234953.1 TIGRFAM: hydroxymethylbutenyl pyrophosphate reductase; PFAM: LytB protein YP_001234954.1 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate YP_001234955.1 PFAM: toluene tolerance family protein YP_001234957.1 PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB YP_001234958.1 PFAM: YdjC family protein YP_001234960.1 PFAM: conserved hypothetical protein 701 YP_001234961.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001234962.1 PFAM: protein of unknown function DUF542, ScdA domain protein; Hemerythrin HHE cation binding domain protein YP_001234964.1 TIGRFAM: putative transcriptional regulator, Rrf2 family; PFAM: protein of unknown function UPF0074 YP_001234965.1 PFAM: helicase domain protein; DbpA, RNA-binding domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like YP_001234966.1 TIGRFAM: 3-oxoacid CoA-transferase, B subunit; PFAM: coenzyme A transferase YP_001234967.1 TIGRFAM: 3-oxoacid CoA-transferase, A subunit; PFAM: coenzyme A transferase YP_001234968.1 TIGRFAM: acetyl-CoA acetyltransferase; beta-ketoadipyl CoA thiolase; PFAM: Thiolase YP_001234969.1 TIGRFAM: protocatechuate 3,4-dioxygenase, alpha subunit; PFAM: intradiol ring-cleavage dioxygenase YP_001234970.1 TIGRFAM: protocatechuate 3,4-dioxygenase, beta subunit; PFAM: intradiol ring-cleavage dioxygenase YP_001234971.1 catalyzes the formation of protocatechuate from 4-hydroxybenzoate YP_001234972.1 TIGRFAM: catalase/peroxidase HPI; PFAM: Haem peroxidase YP_001234973.1 PFAM: inner-membrane translocator YP_001234974.1 PFAM: periplasmic binding protein/LacI transcriptional regulator YP_001234975.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001234976.1 PFAM: short-chain dehydrogenase/reductase SDR; KR YP_001234977.1 PFAM: amidohydrolase 2 YP_001234978.1 PFAM: PfkB domain protein YP_001234979.1 catalyzes the formation of 2-dehydro-3-deoxy-D-gluconate from mannonate YP_001234980.1 PFAM: Mannitol dehydrogenase, C-terminal domain; Mannitol dehydrogenase rossman, N-terminal domain YP_001234981.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR YP_001234982.1 PFAM: regulatory protein GntR, HTH; GntR domain protein YP_001234983.1 PFAM: D-galactarate dehydratase/Altronate hydrolase domain protein; SAF domain YP_001234984.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001234985.1 PFAM: inner-membrane translocator; ABC transporter related; SMART: AAA ATPase YP_001234986.1 PFAM: inner-membrane translocator YP_001234987.1 PFAM: Extracellular ligand-binding receptor YP_001234988.1 TIGRFAM: dethiobiotin synthase YP_001234989.1 TIGRFAM: 8-amino-7-oxononanoate synthase; PFAM: aminotransferase, class I and II YP_001234990.1 TIGRFAM: biotin synthase; PFAM: Radical SAM domain protein; biotin and thiamin synthesis associated; SMART: Elongator protein 3/MiaB/NifB YP_001234991.1 catalyzes the formation of S-adenosyl-4-methylthionine-2-oxobutanoate and 7,8-diaminononanoate from S-adenosyl-L-methionine and 8-amino-7-oxononanoate YP_001234993.1 PFAM: protein of unknown function DUF125, transmembrane YP_001234995.1 PFAM: cytochrome B561 YP_001234996.1 TIGRFAM: glutamate--cysteine ligase; PFAM: glutamate--cysteine ligase, GCS2 YP_001234997.1 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase YP_001234998.1 TIGRFAM: 4-hydroxybenzoate polyprenyl transferase; PFAM: UbiA prenyltransferase YP_001235000.1 PFAM: succinate dehydrogenase, cytochrome b subunit YP_001235001.1 PFAM: succinate dehydrogenase, cytochrome b subunit YP_001235002.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol YP_001235003.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase YP_001235004.1 PFAM: ATP-binding region, ATPase domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein YP_001235005.1 PFAM: response regulator receiver; transcriptional regulator domain protein YP_001235006.1 PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP YP_001235007.1 TIGRFAM: amidohydrolase; PFAM: peptidase M20; peptidase dimerisation domain protein YP_001235008.1 PFAM: multiple antibiotic resistance (MarC)-related protein YP_001235009.1 PFAM: regulatory protein, MarR YP_001235010.1 PFAM: secretion protein HlyD family protein YP_001235011.1 TIGRFAM: drug resistance transporter, EmrB/QacA subfamily; PFAM: major facilitator superfamily MFS_1 YP_001235012.1 TIGRFAM: uracil phosphoribosyltransferase; PFAM: phosphoribosyltransferase YP_001235013.1 PFAM: glycosyl transferase, group 1 YP_001235015.1 PFAM: glycosyl transferase, family 2; Tetratricopeptide TPR_2 repeat protein YP_001235016.1 PFAM: Sel1 domain protein repeat-containing protein YP_001235017.1 TIGRFAM: type I secretion membrane fusion protein, HlyD family; PFAM: secretion protein HlyD family protein YP_001235018.1 PFAM: ABC transporter, transmembrane region; ABC transporter related; SMART: AAA ATPase YP_001235019.1 PFAM: GCN5-related N-acetyltransferase YP_001235020.1 With MotB forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine YP_001235021.1 PFAM: OmpA/MotB domain protein YP_001235022.1 PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit YP_001235023.1 PFAM: glycosyl transferase, family 39 YP_001235024.1 PFAM: glycosyl transferase, family 2; GtrA family protein YP_001235025.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein YP_001235026.1 PFAM: oxidoreductase, molybdopterin binding YP_001235027.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation YP_001235028.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis YP_001235029.1 PFAM: Lytic transglycosylase, catalytic YP_001235030.1 PFAM: phosphatidylglycerophosphatase A YP_001235031.1 PFAM: CinA domain protein YP_001235032.1 PFAM: EAL domain protein; SMART: PAS domain containing protein YP_001235033.1 PFAM: Chromate transporter YP_001235034.1 PFAM: Chromate transporter YP_001235035.1 TIGRFAM: phosphate ABC transporter, periplasmic phosphate-binding protein; PFAM: extracellular solute-binding protein, family 1 YP_001235036.1 TIGRFAM: phosphate ABC transporter, inner membrane subunit PstC; PFAM: binding-protein-dependent transport systems inner membrane component YP_001235037.1 TIGRFAM: phosphate ABC transporter, inner membrane subunit PstA; PFAM: binding-protein-dependent transport systems inner membrane component YP_001235038.1 PFAM: YbaK/prolyl-tRNA synthetase associated region YP_001235040.1 TIGRFAM: oligoendopeptidase, M3 family; PFAM: peptidase M3A and M3B, thimet/oligopeptidase F YP_001235041.1 is a component of the macrolide binding site in the peptidyl transferase center YP_001235042.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme YP_001235043.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3 YP_001235044.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA YP_001235045.1 PFAM: adenylate kinase; adenylate kinase, lid domain protein YP_001235046.1 TIGRFAM: preprotein translocase, SecY subunit; PFAM: SecY protein YP_001235047.1 late assembly protein YP_001235048.1 PFAM: ribosomal protein L30 YP_001235049.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance YP_001235050.1 TIGRFAM: ribosomal protein L18; PFAM: ribosomal protein L18P/L5E YP_001235051.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance YP_001235052.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit YP_001235053.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif YP_001235054.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13 YP_001235055.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel YP_001235056.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase YP_001235057.1 primary binding protein; helps mediate assembly; involved in translation fidelity YP_001235058.1 one of the stabilizing components for the large ribosomal subunit YP_001235059.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e YP_001235060.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation YP_001235061.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center YP_001235062.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA YP_001235063.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation YP_001235064.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel YP_001235065.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA YP_001235066.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin YP_001235067.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex YP_001235068.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu YP_001235069.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit YP_001235070.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance YP_001235071.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter YP_001235072.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme YP_001235073.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors YP_001235074.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit YP_001235075.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA YP_001235076.1 binds directly to 23S ribosomal RNA YP_001235077.1 PFAM: OmpW family protein YP_001235078.1 PFAM: aldo/keto reductase YP_001235079.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation YP_001235080.1 TIGRFAM: HAD-superfamily subfamily IIA hydrolase like protein; HAD-superfamily hydrolase, subfamily IIA; PFAM: Haloacid dehalogenase domain protein hydrolase YP_001235081.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors YP_001235083.1 PFAM: fumarylacetoacetate (FAA) hydrolase YP_001235084.1 catalyzes the formation of pyruvate and beta-alanine from L-alanine and 3-oxopropanoate YP_001235085.1 PFAM: aldehyde dehydrogenase YP_001235086.1 PFAM: peptidase S49 YP_001235087.1 PFAM: uncharacterised conserved protein UCP032025 YP_001235088.1 PFAM: aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead; aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding YP_001235090.1 PFAM: amine oxidase; FAD dependent oxidoreductase YP_001235091.1 PFAM: inner-membrane translocator YP_001235092.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001235093.1 PFAM: periplasmic binding protein/LacI transcriptional regulator YP_001235095.1 PFAM: ABC transporter, transmembrane region; ABC transporter related; SMART: AAA ATPase YP_001235096.1 PFAM: NUDIX hydrolase YP_001235097.1 PFAM: Glutathione S-transferase, N-terminal domain YP_001235098.1 PFAM: oxidoreductase, molybdopterin binding; Mo-co oxidoreductase dimerisation domain YP_001235100.1 PFAM: TrkA-N domain protein; sodium/hydrogen exchanger YP_001235101.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region YP_001235102.1 TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase; PFAM: DAHP synthetase, class II YP_001235104.1 PFAM: protein of unknown function DUF937 YP_001235106.1 NH(3)-dependent; catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers YP_001235108.1 PFAM: histone family protein DNA-binding protein YP_001235110.1 TIGRFAM: cell division topological specificity factor MinE; PFAM: Septum formation topological specificity factor MinE YP_001235111.1 TIGRFAM: septum site-determining protein MinD; PFAM: Cobyrinic acid a,c-diamide synthase YP_001235112.1 blocks the formation of polar Z-ring septums YP_001235113.1 PFAM: oxidoreductase domain protein YP_001235115.1 PFAM: lipolytic enzyme, G-D-S-L family YP_001235117.1 TIGRFAM: recombination protein RecR; PFAM: RecR protein YP_001235118.1 PFAM: conserved hypothetical protein 103 YP_001235119.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA YP_001235120.1 PFAM: NUDIX hydrolase YP_001235121.1 stationary phase protein that binds TrpR repressor YP_001235122.1 PFAM: metallophosphoesterase YP_001235124.1 TIGRFAM: conserved hypothetical membrane protein YP_001235126.1 PFAM: ATPase associated with various cellular activities, AAA_3; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase YP_001235127.1 PFAM: protein of unknown function DUF1285 YP_001235128.1 PFAM: NUDIX hydrolase YP_001235129.1 PFAM: Polynucleotide adenylyltransferase region YP_001235130.1 PFAM: ribosomal RNA methyltransferase RrmJ/FtsJ YP_001235131.1 PFAM: Ppx/GppA phosphatase YP_001235132.1 PFAM: Transketolase, central region YP_001235133.1 TIGRFAM: ribosomal subunit interface protein; PFAM: sigma 54 modulation protein/ribosomal protein S30EA YP_001235134.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma 54 factor is responsible for the expression of enzymes involved in nitrogen assimilation and metabolism; the rhizobia often have 2 copies of this sigma factor; in Rhizobium etli RpoN1 shown to be involved in the assimilation of several nitrogen and carbon sources during free-living aerobic growth and RpoN2 is involved in symbiotic nitrogen fixation; in Bradyrhizobium both RpoN1 and N2 are functional in free-living and symbiotic conditions, rpoN1 gene was regulated in response to oxygen YP_001235135.1 PFAM: type II secretion system protein YP_001235136.1 PFAM: type II secretion system protein YP_001235137.1 PFAM: type II secretion system protein E YP_001235139.1 PFAM: SAF domain YP_001235140.1 PFAM: Flp/Fap pilin component YP_001235141.1 PFAM: PfkB domain protein YP_001235142.1 PFAM: protein of unknown function DUF583 YP_001235144.1 catalyzes the second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione YP_001235146.1 PFAM: cell wall hydrolase/autolysin YP_001235148.1 catalyzes the formation of 2-oxoglutarate from isocitrate YP_001235149.1 TIGRFAM: drug resistance transporter, EmrB/QacA subfamily; PFAM: major facilitator superfamily MFS_1 YP_001235150.1 TIGRFAM: 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; PFAM: MECDP-synthase YP_001235151.1 TIGRFAM: putative TIM-barrel protein, nifR3 family; PFAM: dihydrouridine synthase, DuS YP_001235152.1 TIGRFAM: PAS sensor protein; PFAM: ATP-binding region, ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein YP_001235153.1 TIGRFAM: nitrogen regulation protein NR(I); PFAM: response regulator receiver; sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase YP_001235154.1 TIGRFAM: PAS sensor protein; PFAM: ATP-binding region, ATPase domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein YP_001235155.1 PFAM: response regulator receiver; sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; SMART: AAA ATPase YP_001235156.1 PFAM: TonB-dependent receptor YP_001235157.1 TIGRFAM: single-strand binding protein; PFAM: single-strand binding protein/Primosomal replication protein n YP_001235158.1 TIGRFAM: cytochrome d ubiquinol oxidase, subunit II; PFAM: cytochrome bd ubiquinol oxidase, subunit II YP_001235159.1 PFAM: cytochrome bd ubiquinol oxidase, subunit I YP_001235161.1 PFAM: protein of unknown function UPF0187 YP_001235162.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001235163.1 TIGRFAM: oxidoreductase alpha (molybdopterin) subunit; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region YP_001235164.1 PFAM: Methyltransferase type 11; Methyltransferase type 12 YP_001235165.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate YP_001235167.1 required for the assembly and function of the DNAX complex which are required for the assembly of the beta subunit onto primed DNA YP_001235169.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase YP_001235172.1 PFAM: thiamine monophosphate synthase YP_001235173.1 PFAM: alanine racemase domain protein YP_001235174.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding YP_001235175.1 PFAM: protein of unknown function DUF445 YP_001235176.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-diphosphate and nicotinate from nicotinate D-ribonucleotide and diphosphate YP_001235178.1 TIGRFAM: ribose-phosphate pyrophosphokinase; PFAM: phosphoribosyltransferase YP_001235180.1 PFAM: phosphoribosyltransferase YP_001235182.1 PFAM: Patatin YP_001235183.1 PFAM: major facilitator superfamily MFS_1 YP_001235184.1 PFAM: Transketolase, central region YP_001235185.1 PFAM: regulatory protein, AsnC/Lrp family YP_001235186.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein YP_001235187.1 PFAM: major facilitator superfamily MFS_1 YP_001235188.1 PFAM: Rieske [2Fe-2S] domain protein YP_001235189.1 PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes; aromatic amino acid beta-eliminating lyase/threonine aldolase YP_001235190.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase YP_001235191.1 PFAM: FAD dependent oxidoreductase YP_001235192.1 PFAM: FAD dependent oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase YP_001235193.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001235194.1 TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter, C-terminal domain protein; SMART: AAA ATPase YP_001235195.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001235196.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001235197.1 PFAM: extracellular solute-binding protein, family 5 YP_001235198.1 PFAM: alpha/beta hydrolase fold YP_001235199.1 PFAM: phospholipid/glycerol acyltransferase YP_001235200.1 PFAM: Lysine exporter protein (LYSE/YGGA) YP_001235201.1 PFAM: Paraquat-inducible protein A YP_001235202.1 PFAM: Mammalian cell entry related domain protein YP_001235203.1 PFAM: protein of unknown function DUF330 YP_001235204.1 PFAM: protein phosphatase 2C domain protein YP_001235206.1 PFAM: ImcF domain protein; protein of unknown function DUF1215 YP_001235207.1 PFAM: OmpA/MotB domain protein YP_001235208.1 PFAM: protein of unknown function DUF876 YP_001235210.1 PFAM: Forkhead-associated protein YP_001235212.1 PFAM: Rhs element Vgr protein; Gp5 domain protein YP_001235213.1 PFAM: surface antigen variable number repeat protein; Polypeptide-transport-associated domain protein, ShlB-type YP_001235214.1 TIGRFAM: filamentous haemagglutinin family outer membrane protein; PFAM: Haemagluttinin repeat-containing protein; filamentous haemagglutinin domain protein YP_001235216.1 PFAM: protein kinase; SMART: tyrosine protein kinase; serine/threonine protein kinase YP_001235217.1 PFAM: cytochrome c, class I YP_001235219.1 TIGRFAM: ATP-dependent DNA helicase, RecQ family; ATP-dependent DNA helicase RecQ; PFAM: helicase domain protein; HRDC domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like YP_001235220.1 PFAM: cyclic nucleotide-binding; regulatory protein, Crp YP_001235221.1 TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes YP_001235222.1 TIGRFAM: aminopeptidase N; PFAM: peptidase M1, membrane alanine aminopeptidase; peptidase M61 domain protein YP_001235223.1 PFAM: protein of unknown function DUF482 YP_001235224.1 PFAM: protein of unknown function DUF6, transmembrane YP_001235225.1 PFAM: CsbD family protein YP_001235226.1 PFAM: transposase, mutator type YP_001235227.1 PFAM: amino acid permease-associated region YP_001235228.1 PFAM: pyridoxamine 5'-phosphate oxidase-related, FMN-binding YP_001235229.1 PFAM: Glutathione S-transferase, N-terminal domain YP_001235230.1 PFAM: aminoglycoside phosphotransferase YP_001235231.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain YP_001235232.1 PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein YP_001235233.1 probable dehydrogenase YP_001235234.1 TIGRFAM: thiamine-monophosphate kinase; PFAM: AIR synthase related protein domain protein YP_001235235.1 TIGRFAM: transcription antitermination factor NusB; PFAM: NusB/RsmB/TIM44 YP_001235236.1 PFAM: 6,7-dimethyl-8-ribityllumazine synthase YP_001235237.1 PFAM: 3,4-dihydroxy-2-butanone 4-phosphate synthase; GTP cyclohydrolase II YP_001235238.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine YP_001235239.1 TIGRFAM: riboflavin biosynthesis protein RibD; PFAM: CMP/dCMP deaminase, zinc-binding; bifunctional deaminase-reductase domain protein YP_001235240.1 PFAM: ATP-cone domain protein YP_001235241.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate YP_001235242.1 TIGRFAM: sugar-phosphate isomerase, RpiB/LacA/LacB family; ribose 5-phosphate isomerase B; PFAM: Ribose/galactose isomerase YP_001235243.1 PFAM: protein of unknown function DUF343 YP_001235244.1 PFAM: protein of unknown function DUF971 YP_001235245.1 PFAM: Thioredoxin domain YP_001235246.1 PFAM: peptidase S16, lon domain protein YP_001235247.1 PFAM: type III secretion exporter YP_001235248.1 PFAM: type III secretion system inner membrane R protein YP_001235249.1 PFAM: export protein FliQ, family 3 YP_001235250.1 PFAM: flagellar hook-basal body complex protein FliE YP_001235251.1 with FlgF and B makes up the proximal portion of the flagellar basal body rod YP_001235253.1 FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus YP_001235254.1 PFAM: ATP-binding region, ATPase domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein YP_001235255.1 PFAM: Patatin YP_001235256.1 PFAM: ribosomal protein L34 YP_001235257.1 TIGRFAM: ribonuclease P protein component; PFAM: ribonuclease P protein YP_001235258.1 PFAM: protein of unknown function DUF37 YP_001235259.1 PFAM: 60 kDa inner membrane insertion protein YP_001235260.1 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential YP_001235261.1 catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate YP_001235262.1 PFAM: chemotaxis sensory transducer YP_001235263.1 PFAM: CBS domain containing protein; protein of unknown function DUF21; transporter-associated region YP_001235264.1 PFAM: glycosyl transferase, family 2 YP_001235265.1 catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis YP_001235266.1 TIGRFAM: 3-isopropylmalate dehydratase, small subunit; PFAM: aconitate hydratase domain protein YP_001235267.1 dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate YP_001235268.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site YP_001235269.1 TIGRFAM: tRNA (guanine-N1)-methyltransferase; PFAM: tRNA (guanine-N1-)-methyltransferase YP_001235270.1 TIGRFAM: 16S rRNA processing protein RimM; PFAM: PRC-barrel domain protein YP_001235271.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity YP_001235272.1 TIGRFAM: signal recognition particle protein; PFAM: GTP-binding signal recognition particle SRP54, G- domain; Signal peptide binding (SRP54) M- domain protein; GTP-binding signal recognition particle SRP54, helical bundle; SMART: AAA ATPase YP_001235273.1 PFAM: NAD(P) transhydrogenase, beta subunit YP_001235275.1 PFAM: alanine dehydrogenase/PNT domain protein YP_001235276.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates YP_001235277.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001235279.1 PFAM: GntR domain protein YP_001235280.1 PFAM: peptidase M32, carboxypeptidase Taq metallopeptidase YP_001235282.1 PFAM: cytochrome c oxidase, subunit III YP_001235283.1 converts protoheme IX and farnesyl diphosphate to heme O YP_001235284.1 PFAM: cytochrome c oxidase, subunit I YP_001235285.1 PFAM: cytochrome c oxidase, subunit II; cytochrome C oxidase subunit II, transmembrane region YP_001235286.1 PFAM: Methionine biosynthesis MetW protein; Methyltransferase type 11; Methyltransferase type 12 YP_001235287.1 PFAM: GcrA cell cycle regulator YP_001235288.1 PFAM: protein of unknown function DUF1058 YP_001235289.1 PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein YP_001235291.1 PFAM: aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead; aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding YP_001235292.1 PFAM: ferredoxin; [2Fe-2S]-binding domain protein YP_001235293.1 PFAM: molybdopterin dehydrogenase, FAD-binding YP_001235294.1 PFAM: General substrate transporter; major facilitator superfamily MFS_1 YP_001235295.1 PFAM: ATP-binding region, ATPase domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein YP_001235296.1 PFAM: response regulator receiver; transcriptional regulator domain protein YP_001235297.1 PFAM: Orn/DAP/Arg decarboxylase 2 YP_001235298.1 PFAM: dienelactone hydrolase YP_001235300.1 PFAM: glycosyl transferase, family 2 YP_001235301.1 catalyzes the formation of phosphoenolpyruvate from pyruvate YP_001235303.1 glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_001235305.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain YP_001235306.1 TIGRFAM: acetyl-CoA carboxylase, carboxyl transferase, alpha subunit; PFAM: acetyl-CoA carboxylase, alpha subunit YP_001235308.1 catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine YP_001235309.1 PFAM: S-adenosylmethionine decarboxylase related YP_001235311.1 PFAM: glycosyl transferase, group 1 YP_001235312.1 PFAM: glycosyl transferase, family 9 YP_001235313.1 catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr) YP_001235316.1 TIGRFAM: beta-ketoadipate pathway transcriptional regulators, PcaR/PcaU/PobR family; PFAM: regulatory protein, IclR; beta-ketoadipate transcriptional regulator, PcaR/PcaU/PobR YP_001235317.1 PFAM: OsmC family protein YP_001235318.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001235319.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001235320.1 PFAM: inner-membrane translocator YP_001235321.1 PFAM: inner-membrane translocator YP_001235322.1 PFAM: Extracellular ligand-binding receptor YP_001235325.1 catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine YP_001235326.1 PFAM: major facilitator superfamily MFS_1 YP_001235327.1 catalyzes the formation of 3-methyl-2-oxobutanoate from 2,3,-dihydroxy-3-methylbutanoate YP_001235328.1 PFAM: aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead; aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding YP_001235329.1 PFAM: glycosyl transferase, family 2 YP_001235330.1 PFAM: inner-membrane translocator YP_001235331.1 PFAM: inner-membrane translocator YP_001235332.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001235333.1 PFAM: periplasmic binding protein/LacI transcriptional regulator YP_001235335.1 PFAM: transcriptional regulator PadR family protein YP_001235342.1 PFAM: transposase, IS4 family protein YP_001235343.1 PFAM: peptidase M20; peptidase dimerisation domain protein YP_001235344.1 TIGRFAM: amidohydrolase; PFAM: peptidase M20; peptidase dimerisation domain protein YP_001235346.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001235347.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR YP_001235348.1 PFAM: Asp/Glu racemase YP_001235349.1 catalyzes the formation of 2-oxobutanoate from L-threonine YP_001235350.1 PFAM: inner-membrane translocator YP_001235351.1 PFAM: inner-membrane translocator YP_001235352.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001235353.1 PFAM: periplasmic binding protein/LacI transcriptional regulator YP_001235354.1 PFAM: regulatory protein, IclR YP_001235355.1 PFAM: penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain YP_001235356.1 PFAM: regulatory protein GntR, HTH; GntR domain protein YP_001235357.1 PFAM: beta-Ig-H3/fasciclin YP_001235358.1 bifunctional arginine biosynthesis protein ArgJ; functions at the 1st and 5th steps in arginine biosynthesis; involved in synthesis of acetylglutamate from glutamate and acetyl-CoA and ornithine by transacetylation between acetylornithine and glutmate YP_001235359.1 PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase YP_001235360.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins YP_001235362.1 PFAM: regulatory protein, MarR; transcriptional regulator TrmB YP_001235363.1 forms a direct contact with the tRNA during translation YP_001235364.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit YP_001235365.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility C-terminal domain YP_001235366.1 TIGRFAM: polyhydroxyalkanoate synthesis repressor PhaR; PFAM: PHB accumulation regulatory domain protein; PHA accumulation regulator DNA-binding protein YP_001235367.1 PFAM: protein of unknown function DUF81 YP_001235369.1 PFAM: alpha/beta hydrolase fold YP_001235370.1 TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase YP_001235371.1 TIGRFAM: 3-oxoacid CoA-transferase, A subunit; PFAM: coenzyme A transferase YP_001235372.1 TIGRFAM: 3-oxoacid CoA-transferase, B subunit; PFAM: coenzyme A transferase YP_001235373.1 TIGRFAM: 4-aminobutyrate aminotransferase; PFAM: aminotransferase, class I and II; aminotransferase class-III YP_001235375.1 PFAM: protein of unknown function UPF0102 YP_001235376.1 PFAM: helix-turn-helix domain protein YP_001235377.1 PFAM: Rhodanese domain protein YP_001235378.1 TIGRFAM: cystathionine beta-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes YP_001235379.1 PFAM: phosphoribosyl-AMP cyclohydrolase YP_001235380.1 TIGRFAM: iron-sulfur cluster assembly accessory protein; PFAM: HesB/YadR/YfhF-family protein YP_001235381.1 PFAM: protein of unknown function DUF59 YP_001235382.1 TIGRFAM: SUF system FeS assembly protein, NifU family; PFAM: nitrogen-fixing NifU domain protein YP_001235383.1 TIGRFAM: cysteine desulfurase, SufS subfamily; PFAM: aminotransferase, class V; aromatic amino acid beta-eliminating lyase/threonine aldolase YP_001235384.1 TIGRFAM: FeS assembly protein SufD; PFAM: SufBD protein YP_001235385.1 TIGRFAM: FeS assembly ATPase SufC; PFAM: ABC transporter related; SMART: AAA ATPase YP_001235386.1 with SufCD activates cysteine desulfurase SufS YP_001235387.1 PFAM: protein of unknown function UPF0074 YP_001235388.1 TIGRFAM: phosphoglycolate phosphatase ; HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase YP_001235389.1 forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis YP_001235390.1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source YP_001235394.1 TIGRFAM: bacteriochlorophyll 4-vinyl reductase; PFAM: 4-vinyl reductase, 4VR YP_001235395.1 TIGRFAM: magnesium-protoporphyrin IX monomethyl ester anaerobic oxidative cyclase; PFAM: cobalamin B12-binding domain protein; Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB YP_001235399.1 PFAM: HpcH/HpaI aldolase YP_001235400.1 TIGRFAM: pyrrolidone-carboxylate peptidase; PFAM: peptidase C15, pyroglutamyl peptidase I YP_001235401.1 PFAM: alpha/beta hydrolase fold YP_001235402.1 TIGRFAM: acetate--CoA ligase; PFAM: AMP-dependent synthetase and ligase YP_001235403.1 NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate YP_001235404.1 lipoyl/octanoyltransferase; catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system H protein YP_001235405.1 PFAM: polysaccharide biosynthesis protein YP_001235416.1 PFAM: IstB domain protein ATP-binding protein; IstB ATP binding N-terminal domain protein; SMART: AAA ATPase YP_001235417.1 PFAM: Integrase, catalytic region YP_001235423.1 PFAM: phage integrase family protein YP_001235426.1 PFAM: Myo-inositol catabolism IolB domain protein YP_001235427.1 PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; thiamine pyrophosphate enzyme, central region; thiamine pyrophosphate enzyme TPP binding domain protein YP_001235428.1 PFAM: PfkB domain protein YP_001235429.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001235430.1 PFAM: inner-membrane translocator YP_001235432.1 PFAM: Xylose isomerase domain protein TIM barrel YP_001235433.1 PFAM: oxidoreductase domain protein; Oxidoreductase, C-terminal domain YP_001235434.1 PFAM: Xylose isomerase domain protein TIM barrel YP_001235435.1 PFAM: regulatory protein, LacI YP_001235437.1 PFAM: short-chain dehydrogenase/reductase SDR; KR YP_001235438.1 PFAM: Xylose isomerase domain protein TIM barrel YP_001235439.1 PFAM: helix-turn-helix protein RpiR; sugar isomerase (SIS) YP_001235440.1 PFAM: HpcH/HpaI aldolase YP_001235441.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding YP_001235442.1 PFAM: oxidoreductase domain protein; Oxidoreductase, C-terminal domain YP_001235443.1 PFAM: oxidoreductase domain protein; Oxidoreductase, C-terminal domain YP_001235446.1 PFAM: NADH/Ubiquinone/plastoquinone (complex I) YP_001235447.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001235449.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription YP_001235453.1 PFAM: protein of unknown function DUF1501 YP_001235454.1 PFAM: DNA photolyase domain protein YP_001235455.1 PFAM: transposase, IS204/IS1001/IS1096/IS1165 family protein YP_001235456.1 PFAM: DNA photolyase, FAD-binding YP_001235461.1 PFAM: phage integrase family protein; phage integrase domain protein SAM domain protein YP_001235462.1 PFAM: putative transposase YP_001235463.1 PFAM: globin YP_001235465.1 PFAM: Resolvase, N-terminal domain; Recombinase YP_001235466.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase; Male sterility C-terminal domain YP_001235467.1 TIGRFAM: phosphoheptose isomerase YP_001235468.1 TIGRFAM: 3-hydroxybutyrate dehydrogenase; PFAM: short-chain dehydrogenase/reductase SDR; KR YP_001235470.1 PFAM: SOUL heme-binding protein YP_001235471.1 PFAM: transposase, IS4 family protein YP_001235473.1 PFAM: ferric-uptake regulator YP_001235474.1 PFAM: AMP-dependent synthetase and ligase YP_001235475.1 PFAM: major facilitator superfamily MFS_1 YP_001235476.1 PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein YP_001235477.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes YP_001235478.1 TIGRFAM: ribonuclease D; PFAM: HRDC domain protein; 3'-5' exonuclease YP_001235479.1 PFAM: ABC-3 protein YP_001235480.1 PFAM: ABC-3 protein YP_001235481.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001235482.1 PFAM: periplasmic solute binding protein YP_001235483.1 PFAM: 4-oxalocrotonate tautomerase YP_001235485.1 PFAM: MOFRL domain protein YP_001235488.1 PFAM: tRNA synthetase, class II (D, K and N) YP_001235489.1 TIGRFAM: lysine 2,3-aminomutase YodO family protein; PFAM: Radical SAM domain protein YP_001235490.1 catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis YP_001235491.1 TIGRFAM: acetyl-CoA carboxylase, biotin carboxyl carrier protein; PFAM: biotin/lipoyl attachment domain-containing protein YP_001235492.1 an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism YP_001235494.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein YP_001235495.1 TIGRFAM: oxidoreductase alpha (molybdopterin) subunit; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region YP_001235496.1 PFAM: major intrinsic protein YP_001235497.1 TIGRFAM: glycerol kinase; PFAM: carbohydrate kinase, FGGY YP_001235498.1 in Escherichia coli this homodimeric enzyme is expressed under aerobic conditions; anaerobic expression is repressed by the arcAB system; converts sn-glycerol-3-phosphate and ubiquinone-8 to dihydroxy acetone phosphate and ubiquinol-8; associates with the cytoplasmic membrane YP_001235499.1 PFAM: regulatory protein, DeoR; Helix-turn-helix, type 11 domain protein YP_001235500.1 PFAM: chemotaxis sensory transducer YP_001235501.1 PFAM: Glutathione S-transferase, N-terminal domain YP_001235502.1 PFAM: aldehyde dehydrogenase YP_001235503.1 catalyzes the formation of 4-aminobutanoate from 4-aminobutanal; involved in putrescine degradation YP_001235504.1 PFAM: amino acid permease-associated region YP_001235505.1 PFAM: helix-turn-helix- domain containing protein, AraC type YP_001235506.1 PFAM: glutamine synthetase, catalytic region YP_001235507.1 PFAM: iron-containing alcohol dehydrogenase YP_001235508.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein YP_001235509.1 catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase YP_001235510.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation YP_001235511.1 PFAM: short-chain dehydrogenase/reductase SDR; KR YP_001235512.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase; Male sterility C-terminal domain YP_001235513.1 PFAM: Cupin 2, conserved barrel domain protein YP_001235514.1 PFAM: Methyltransferase type 11; Methyltransferase type 12 YP_001235515.1 PFAM: Amidase YP_001235516.1 TIGRFAM: parB-like partition protein; PFAM: ParB domain protein nuclease YP_001235517.1 PFAM: Cobyrinic acid a,c-diamide synthase YP_001235518.1 TIGRFAM: methyltransferase GidB; PFAM: glucose inhibited division protein YP_001235519.1 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs YP_001235520.1 TIGRFAM: tRNA modification GTPase TrmE; small GTP-binding protein; PFAM: GTP-binding protein, HSR1-related YP_001235522.1 PFAM: protein of unknown function DUF255 YP_001235524.1 binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB YP_001235525.1 PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein YP_001235526.1 PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; HI0933 family protein; FAD dependent oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase YP_001235527.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001235528.1 PFAM: glycosyl transferase, family 4 YP_001235530.1 PFAM: glycosyl transferase, family 2 YP_001235535.1 PFAM: Eco57I restriction endonuclease YP_001235540.1 PFAM: phage integrase family protein YP_001235541.1 PFAM: type III effector Hrp-dependent outers YP_001235542.1 PFAM: Xylose isomerase domain protein TIM barrel YP_001235543.1 PFAM: 6-phosphogluconate dehydrogenase, NAD-binding; 3-hydroxyacyl-CoA dehydrogenase, NAD-binding YP_001235544.1 PFAM: regulatory protein, LacI; periplasmic binding protein/LacI transcriptional regulator YP_001235545.1 PFAM: 6-phosphogluconate dehydrogenase, NAD-binding YP_001235546.1 PFAM: class II aldolase/adducin family protein YP_001235547.1 PFAM: Antibiotic biosynthesis monooxygenase YP_001235549.1 PFAM: major facilitator superfamily MFS_1 YP_001235550.1 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates YP_001235551.1 PFAM: putative ammonia monooxygenase YP_001235552.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001235553.1 TIGRFAM: thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A YP_001235554.1 PFAM: regulatory protein, AsnC/Lrp family YP_001235556.1 PFAM: surface antigen (D15); surface antigen variable number repeat protein YP_001235557.1 PFAM: outer membrane chaperone Skp (OmpH) YP_001235558.1 adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis YP_001235559.1 TIGRFAM: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ; PFAM: Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase, FabA/FabZ YP_001235560.1 catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis YP_001235561.1 PFAM: protein of unknown function DUF1009 YP_001235562.1 TIGRFAM: lactoylglutathione lyase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase YP_001235568.1 PFAM: transposase, IS204/IS1001/IS1096/IS1165 family protein YP_001235571.1 ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence YP_001235573.1 TIGRFAM: 2-dehydropantoate 2-reductase; PFAM: NADP oxidoreductase, coenzyme F420-dependent; Ketopantoate reductase ApbA/PanE, N-terminal domain protein; Ketopantoate reductase ApbA/PanE, C-terminal domain protein YP_001235574.1 PFAM: AMP-dependent synthetase and ligase YP_001235575.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase YP_001235576.1 PFAM: Heavy metal transport/detoxification protein YP_001235577.1 TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; copper-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: Haloacid dehalogenase domain protein hydrolase; Heavy metal transport/detoxification protein; E1-E2 ATPase-associated domain protein YP_001235578.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR YP_001235579.1 PFAM: dihydrodipicolinate synthetase YP_001235580.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding YP_001235581.1 catalyzes the formation of 3-methyl-2-oxobutanoate from 2,3,-dihydroxy-3-methylbutanoate YP_001235582.1 PFAM: Dimethylmenaquinone methyltransferase YP_001235583.1 PFAM: conserved hypothetical protein 701 YP_001235584.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase domain protein hydrolase YP_001235585.1 PFAM: ferrochelatase YP_001235586.1 catalyzes the formation of coproporphyrinogen from uroporphyrinogen III YP_001235587.1 PFAM: protein of unknown function DUF299 YP_001235588.1 TIGRFAM: methylated-DNA--protein-cysteine methyltransferase; PFAM: methylated-DNA-[protein]-cysteine S-methyltransferase YP_001235589.1 PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein YP_001235591.1 PFAM: CHRD domain containing protein YP_001235592.1 TIGRFAM: dihydroneopterin aldolase YP_001235593.1 PFAM: natural resistance-associated macrophage protein YP_001235594.1 TIGRFAM: 3-carboxy-cis,cis-muconate cycloisomerase; PFAM: fumarate lyase YP_001235595.1 PFAM: permease for cytosine/purines, uracil, thiamine, allantoin YP_001235596.1 PFAM: Sel1 domain protein repeat-containing protein YP_001235599.1 catalyzes the hydrolysis of pyrophosphate to phosphate YP_001235600.1 PFAM: NAD-dependent epimerase/dehydratase YP_001235603.1 PFAM: protein of unknown function DUF710 YP_001235604.1 PFAM: 5-formyltetrahydrofolate cyclo-ligase YP_001235605.1 PFAM: aminotransferase, class I and II YP_001235606.1 TIGRFAM: signal recognition particle-docking protein FtsY; PFAM: GTP-binding signal recognition particle SRP54, G- domain; GTP-binding signal recognition particle SRP54, helical bundle; SMART: AAA ATPase YP_001235607.1 TIGRFAM: RNA modification enzyme, MiaB family; MiaB-like tRNA modifying enzyme; PFAM: Radical SAM domain protein; Protein of unknown function UPF0004-like; SMART: Elongator protein 3/MiaB/NifB YP_001235608.1 PFAM: diaminopimelate epimerase YP_001235609.1 PFAM: amino acid permease-associated region YP_001235610.1 TIGRFAM: endonuclease III; PFAM: helix-hairpin-helix motif; HhH-GPD family protein YP_001235612.1 PFAM: General substrate transporter; major facilitator superfamily MFS_1 YP_001235613.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth YP_001235614.1 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring YP_001235615.1 PFAM: Usg family protein YP_001235617.1 TIGRFAM: phage uncharacterized protein; PFAM: protein of unknown function DUF264 YP_001235632.1 TIGRFAM: phage baseplate assembly protein V YP_001235634.1 PFAM: Baseplate J family protein YP_001235637.1 SMART: Parallel beta-helix repeat YP_001235644.1 catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate YP_001235646.1 PFAM: protein of unknown function UPF0118 YP_001235647.1 TIGRFAM: phosphoribosylformylglycinamidine cyclo-ligase; PFAM: AIR synthase related protein; AIR synthase related protein domain protein YP_001235648.1 glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate YP_001235649.1 PFAM: protein of unknown function DUF6, transmembrane YP_001235650.1 catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation YP_001235651.1 DapATase; functions in arginine biosynthetic pathway; catalyzes the formation of N-acetyl-L-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine YP_001235652.1 PFAM: Ppx/GppA phosphatase YP_001235655.1 involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation; binds to the N-terminal domain of the chaperone ClpA YP_001235656.1 TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: AAA ATPase, central domain protein; Clp N terminal domain protein; ATPase associated with various cellular activities, AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase YP_001235658.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; protein of unknown function DUF224, cysteine-rich region domain protein YP_001235659.1 PFAM: FAD linked oxidase domain protein YP_001235660.1 PFAM: FAD linked oxidase domain protein YP_001235661.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group do not have the motif YP_001235662.1 PFAM: aminotransferase, class IV YP_001235663.1 Catalyzes the phosphorylation of UMP to UDP YP_001235664.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs YP_001235665.1 TIGRFAM: undecaprenyl diphosphate synthase; PFAM: Di-trans-poly-cis-decaprenylcistransferase YP_001235666.1 PFAM: phosphatidate cytidylyltransferase YP_001235667.1 catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate YP_001235668.1 TIGRFAM: putative membrane-associated zinc metalloprotease; PFAM: PDZ/DHR/GLGF domain protein; peptidase M50 YP_001235669.1 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis YP_001235670.1 TIGRFAM: cysteine synthase; cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit YP_001235673.1 TIGRFAM: HAD-superfamily subfamily IIA hydrolase like protein; HAD-superfamily hydrolase, subfamily IIA; PFAM: Haloacid dehalogenase domain protein hydrolase YP_001235674.1 PFAM: carbohydrate kinase, FGGY YP_001235675.1 PFAM: putative sugar-binding domain protein YP_001235676.1 PFAM: extracellular solute-binding protein, family 1 YP_001235677.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001235678.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001235679.1 PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase YP_001235680.1 PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase YP_001235681.1 PFAM: carbohydrate kinase, FGGY YP_001235682.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding YP_001235683.1 PFAM: class II aldolase/adducin family protein YP_001235684.1 in Escherichia coli this homodimeric enzyme is expressed under aerobic conditions; anaerobic expression is repressed by the arcAB system; converts sn-glycerol-3-phosphate and ubiquinone-8 to dihydroxy acetone phosphate and ubiquinol-8; associates with the cytoplasmic membrane YP_001235686.1 PFAM: protein of unknown function UPF0126 YP_001235687.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain YP_001235688.1 PFAM: L-carnitine dehydratase/bile acid-inducible protein F YP_001235690.1 PFAM: MaoC domain protein dehydratase YP_001235691.1 PFAM: short-chain dehydrogenase/reductase SDR; KR YP_001235694.1 PFAM: peptidase C39, bacteriocin processing YP_001235698.1 PFAM: sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; SMART: AAA ATPase YP_001235700.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; Cache, type 2 domain protein YP_001235701.1 PFAM: SMP-30/Gluconolaconase/LRE domain protein YP_001235702.1 PFAM: inner-membrane translocator YP_001235703.1 PFAM: inner-membrane translocator YP_001235704.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001235706.1 PFAM: SMP-30/Gluconolaconase/LRE domain protein YP_001235707.1 PFAM: KDPG and KHG aldolase YP_001235708.1 PFAM: 2-keto-3-deoxy-galactonokinase YP_001235709.1 PFAM: short-chain dehydrogenase/reductase SDR YP_001235710.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001235711.1 PFAM: inner-membrane translocator YP_001235713.1 PFAM: short-chain dehydrogenase/reductase SDR; KR YP_001235715.1 PFAM: periplasmic binding protein/LacI transcriptional regulator YP_001235716.1 PFAM: inner-membrane translocator YP_001235717.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001235718.1 with PaaBCDE catalyzes the hydroxylation of phenylacetyl-CoA YP_001235719.1 with PaaBCDE catalyzes the hydroxylation of phenylacetyl-CoA; involved in phenylacetate degradation YP_001235720.1 TIGRFAM: phenylacetate-CoA oxygenase, PaaI subunit; PFAM: phenylacetic acid catabolic family protein YP_001235721.1 TIGRFAM: phenylacetate-CoA oxygenase, PaaJ subunit; PFAM: protein of unknown function DUF59 YP_001235722.1 TIGRFAM: phenylacetate-CoA oxygenase/reductase, PaaK subunit; PFAM: ferredoxin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein YP_001235725.1 PFAM: C4-dicarboxylate transporter/malic acid transport protein YP_001235726.1 with DhaL and DhaM forms dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone; DhaK is the dihydroxyacetone binding subunit of the dihydroxyacetone kinase YP_001235727.1 TIGRFAM: dihydroxyacetone kinase, L subunit; PFAM: Dak phosphatase YP_001235728.1 TIGRFAM: phosphocarrier, HPr family; dihydroxyacetone kinase, phosphotransfer subunit; PFAM: phosphocarrier HPr protein; PEP-utilizing enzyme; PTS system fructose subfamily IIA component; PEP-utilising enzyme, mobile region; PEP-utilising enzyme domain protein YP_001235730.1 TIGRFAM: Mg chelatase, subunit ChlI; PFAM: magnesium chelatase, ChlI subunit; SMART: AAA ATPase YP_001235731.1 PFAM: DNA repair protein RadC YP_001235732.1 PFAM: Endoribonuclease L-PSP YP_001235733.1 PFAM: CHAP domain containing protein YP_001235734.1 TIGRFAM: dimethyladenosine transferase; PFAM: ribosomal RNA adenine methylase transferase YP_001235735.1 PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase YP_001235736.1 PFAM: OstA family protein; Organic solvent tolerance protein YP_001235737.1 PFAM: permease YjgP/YjgQ family protein YP_001235738.1 PFAM: permease YjgP/YjgQ family protein YP_001235739.1 involved in the de novo synthesis of pyridoxine (Vitamin B6) YP_001235740.1 TIGRFAM: 4-hydroxythreonine-4-phosphate dehydrogenase; PFAM: Pyridoxal phosphate biosynthetic protein PdxA YP_001235742.1 PFAM: heat shock protein Hsp20 YP_001235743.1 RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome YP_001235744.1 PFAM: Methyltransferase type 11; Methyltransferase type 12 YP_001235745.1 PFAM: HhH-GPD family protein YP_001235749.1 PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like YP_001235750.1 PFAM: sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; GAF domain protein; SMART: AAA ATPase YP_001235751.1 PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein YP_001235752.1 PFAM: amidohydrolase 2 YP_001235753.1 PFAM: protein of unknown function DUF59 YP_001235754.1 PFAM: DMSO reductase anchor subunit (DmsC) YP_001235755.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001235756.1 PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region YP_001235757.1 PFAM: Pyridoxal-dependent decarboxylase YP_001235758.1 TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein YP_001235759.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein YP_001235760.1 catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate YP_001235761.1 catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate YP_001235762.1 TIGRFAM: hemolysin A; PFAM: ribosomal RNA methyltransferase RrmJ/FtsJ; RNA-binding S4 domain protein YP_001235763.1 PFAM: helix-turn-helix domain protein YP_001235764.1 PFAM: Fmu (Sun) domain protein; NusB/RsmB/TIM44; methyltransferase small YP_001235765.1 PFAM: protein of unknown function YGGT YP_001235766.1 PFAM: tetrahydrofolate dehydrogenase/cyclohydrolase YP_001235767.1 PFAM: Sporulation domain protein; Lytic transglycosylase, catalytic YP_001235769.1 PFAM: aldo/keto reductase YP_001235770.1 PFAM: GTP cyclohydrolase I YP_001235771.1 protein associated with Co2+ and Mg2+ efflux YP_001235772.1 SMART: Tetratricopeptide domain protein YP_001235773.1 TIGRFAM: 4-diphosphocytidyl-2C-methyl-D-erythritol kinase; PFAM: GHMP kinase; GHMP kinase, C terminal domain protein YP_001235774.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis YP_001235775.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis YP_001235776.1 PFAM: BolA family protein YP_001235777.1 TIGRFAM: glutaredoxin-like protein; PFAM: glutaredoxin YP_001235779.1 biotin-containing enzyme that catalyzes a two step carboxylation of pyruvate to oxaloacetate YP_001235780.1 PFAM: amine oxidase YP_001235781.1 PFAM: multiple antibiotic resistance (MarC)-related protein YP_001235785.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation YP_001235786.1 PFAM: major facilitator superfamily MFS_1 YP_001235787.1 Transcriptional regulator that represses the manganese transporter MntH when manganese is present YP_001235789.1 PFAM: protein of unknown function UPF0118 YP_001235790.1 PFAM: acylphosphatase YP_001235791.1 PFAM: ATP12 ATPase YP_001235792.1 PFAM: AsmA family protein YP_001235794.1 PFAM: protein of unknown function DUF1022 YP_001235795.1 PFAM: Succinylglutamate desuccinylase/aspartoacylase YP_001235796.1 PFAM: CDP-alcohol phosphatidyltransferase YP_001235797.1 catalyzes the decarboxylaton of phospatidyl-L-sering to phosphatidylethanolamine YP_001235798.1 PFAM: Peptidoglycan-binding LysM YP_001235799.1 PFAM: conserved hypothetical protein 730 YP_001235801.1 TIGRFAM: maf protein; PFAM: Maf family protein YP_001235802.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3 YP_001235803.1 PFAM: histidinol dehydrogenase YP_001235804.1 short form of enzyme; requires HisZ for function; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms heteromultimer of HisG and HisZ YP_001235805.1 PFAM: pyruvate carboxyltransferase YP_001235806.1 PFAM: L-carnitine dehydratase/bile acid-inducible protein F YP_001235807.1 PFAM: 6-phosphogluconate dehydrogenase, NAD-binding YP_001235810.1 TIGRFAM: radical SAM enzyme, Cfr family; PFAM: Radical SAM domain protein YP_001235811.1 PFAM: short-chain dehydrogenase/reductase SDR; KR YP_001235812.1 required for 70S ribosome assembly YP_001235814.1 TIGRFAM: pyrroline-5-carboxylate reductase; PFAM: NADP oxidoreductase, coenzyme F420-dependent YP_001235815.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer YP_001235817.1 PFAM: response regulator receiver YP_001235818.1 PFAM: CheW domain protein; ATP-binding region, ATPase domain protein; Signal transducing histidine kinase, homodimeric; Hpt domain protein YP_001235819.1 PFAM: CheW domain protein YP_001235820.1 PFAM: MCP methyltransferase, CheR-type YP_001235821.1 regulates chemotaxis by demethylation of methyl-accepting chemotaxis proteins YP_001235822.1 PFAM: response regulator receiver YP_001235823.1 PFAM: CheD family protein YP_001235826.1 PFAM: protein of unknown function DUF1486 YP_001235827.1 PFAM: beta-lactamase domain protein YP_001235828.1 binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters YP_001235829.1 TIGRFAM: pseudouridine synthase, RluA family; PFAM: RNA-binding S4 domain protein; pseudouridine synthase YP_001235831.1 PFAM: protein of unknown function DUF1555 YP_001235832.1 catalyzes the oxidation of tricarballylate to cis-aconitate; FAD-dependent; required for the utilization of tricarballylate as a carbon and energy source by S. enterica YP_001235833.1 TIGRFAM: CitB domain protein; PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001235834.1 PFAM: General substrate transporter; major facilitator superfamily MFS_1 YP_001235836.1 PFAM: Amidase YP_001235837.1 TIGRFAM: urea amidolyase related protein; biotin carboxylation domain protein; PFAM: biotin/lipoyl attachment domain-containing protein; Allophanate hydrolase subunit 2; Allophanate hydrolase subunit 1; Carbamoyl-phosphate synthase L chain, ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein YP_001235840.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001235841.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001235845.1 PFAM: acriflavin resistance protein YP_001235847.1 PFAM: outer membrane efflux protein YP_001235848.1 PFAM: dihydrodipicolinate synthetase YP_001235849.1 PFAM: protein of unknown function DUF347 YP_001235850.1 TIGRFAM: undecaprenyl diphosphate synthase; PFAM: Di-trans-poly-cis-decaprenylcistransferase YP_001235851.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001235853.1 PFAM: extracellular solute-binding protein, family 3 YP_001235854.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component YP_001235855.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001235856.1 PFAM: fumarate lyase YP_001235857.1 catalyzes the conversion of guanine, xanthine and, to a lesser extent, hypoxanthine to GMP, XMP and IMP, respectively YP_001235858.1 TIGRFAM: export-related chaperone CsaA; PFAM: t-RNA-binding domain protein YP_001235859.1 PFAM: gamma-glutamyltranspeptidase YP_001235861.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene YP_001235862.1 PFAM: Enoyl-CoA hydratase/isomerase YP_001235863.1 TIGRFAM: acetoacetyl-CoA reductase; PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR YP_001235864.1 PFAM: GCN5-related N-acetyltransferase YP_001235865.1 PFAM: OsmC family protein YP_001235866.1 PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein YP_001235869.1 TIGRFAM: polyhydroxyalkanoate depolymerase, intracellular; PFAM: PHB de-polymerase domain protein YP_001235870.1 TIGRFAM: dephospho-CoA kinase; PFAM: Dephospho-CoA kinase YP_001235871.1 TIGRFAM: shikimate 5-dehydrogenase; PFAM: Shikimate/quinate 5-dehydrogenase; Shikimate dehydrogenase substrate binding, N-terminal domain protein YP_001235872.1 PFAM: short-chain dehydrogenase/reductase SDR YP_001235873.1 PFAM: DSBA oxidoreductase YP_001235874.1 produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine YP_001235875.1 TIGRFAM: DNA polymerase III, epsilon subunit; PFAM: Exonuclease, RNase T and DNA polymerase III; SMART: Exonuclease YP_001235876.1 PFAM: peptidase S9, prolyl oligopeptidase active site domain protein; peptidase S9A, prolyl oligopeptidase domain protein beta-propeller YP_001235877.1 PFAM: formate-tetrahydrofolate ligase, FTHFS YP_001235879.1 TIGRFAM: putative agmatinase; PFAM: Arginase/agmatinase/formiminoglutamase YP_001235881.1 catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia YP_001235883.1 PFAM: Lysine exporter protein (LYSE/YGGA) YP_001235884.1 specific inhibitor of chromosomal initiation of replication in vitro; binds the three 13-mers in the origin (oriC) to block initiation of replication; also controls genes involved in arginine transport YP_001235886.1 PFAM: aldo/keto reductase YP_001235887.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001235888.1 PFAM: protein of unknown function DUF849 YP_001235889.1 Converts (S)-3-hydroxyactk-CoA to 3-oxoayl-CoA YP_001235891.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001235892.1 PFAM: inner-membrane translocator YP_001235893.1 PFAM: inner-membrane translocator YP_001235894.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis YP_001235895.1 PFAM: tRNA synthetase, class II (G, H, P and S) YP_001235896.1 PFAM: membrane bound O-acyl transferase, MBOAT family protein YP_001235898.1 PFAM: nucleoside 2-deoxyribosyltransferase YP_001235899.1 PFAM: sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; GAF domain protein; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase YP_001235900.1 PFAM: Pyrrolo-quinoline quinone YP_001235901.1 SMART: extracellular solute-binding protein, family 3 YP_001235902.1 PFAM: cytochrome c, class I YP_001235903.1 catalyzes the reaction of formaldehyde with glutathione to form S-hydroxymethylglutathione YP_001235904.1 PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein YP_001235905.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug YP_001235906.1 PFAM: FAD linked oxidase domain protein YP_001235907.1 PFAM: Pyrrolo-quinoline quinone YP_001235908.1 PFAM: cytochrome c, class I YP_001235909.1 hemoprotein; NADPH dependent; with the alpha subunit (a flavoprotein) catalyzes the reduction of sulfite to sulfide YP_001235910.1 PFAM: phosphoadenosine phosphosulfate reductase YP_001235911.1 PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; FAD-binding domain protein; flavodoxin/nitric oxide synthase YP_001235912.1 TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase YP_001235913.1 TIGRFAM: siroheme synthase YP_001235914.1 PFAM: regulatory protein, AsnC/Lrp family YP_001235915.1 TIGRFAM: molybdenum cofactor synthesis domain; molybdenum cofactor biosynthesis protein B; PFAM: molybdopterin binding domain YP_001235916.1 PFAM: protein of unknown function DUF1295 YP_001235917.1 PFAM: Cyclopropane-fatty-acyl-phospholipid synthase; Methyltransferase type 11; Methyltransferase type 12 YP_001235919.1 PFAM: EAL domain protein YP_001235920.1 SMART: regulatory protein, ArsR YP_001235921.1 TIGRFAM: arsenate reductase; PFAM: arsenate reductase and related YP_001235922.1 TIGRFAM: arsenical pump membrane protein; PFAM: Arsenical pump membrane protein; Citrate transporter YP_001235923.1 PFAM: response regulator receiver; transcriptional regulator domain protein YP_001235924.1 PFAM: GTP cyclohydrolase II YP_001235927.1 PFAM: Septum formation initiator YP_001235928.1 PFAM: dehydrogenase, E1 component YP_001235929.1 catalyzes the oxidative decarboxylation of pyruvate with concomitant acetylation of a lipoic acid-containing dihydrolipoamide acetyltransferase within the complex. The E1 component of the pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase(E2) and lipoamide dehydrogenase YP_001235930.1 TIGRFAM: pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein YP_001235931.1 PFAM: GCN5-related N-acetyltransferase YP_001235932.1 TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; FAD dependent oxidoreductase YP_001235933.1 catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group YP_001235934.1 PFAM: cyclase/dehydrase YP_001235935.1 PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase YP_001235936.1 PFAM: Di-haem cytochrome c peroxidase YP_001235937.1 PFAM: NADPH-dependent FMN reductase YP_001235938.1 PFAM: aldo/keto reductase YP_001235939.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001235941.1 with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit YP_001235942.1 TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; thiamine pyrophosphate enzyme, central region; thiamine pyrophosphate enzyme TPP binding domain protein YP_001235943.1 PFAM: tRNA isopentenyltransferase YP_001235944.1 TIGRFAM: phosphoserine phosphatase SerB; HAD-superfamily hydrolase, subfamily IB (PSPase-like); PFAM: Haloacid dehalogenase domain protein hydrolase YP_001235945.1 PFAM: CoA-binding domain protein YP_001235946.1 PFAM: glycoside hydrolase, family 17 YP_001235947.1 PFAM: peptidase S11, D-alanyl-D-alanine carboxypeptidase 1 YP_001235948.1 TIGRFAM: phasin family protein YP_001235949.1 PFAM: ATP-dependent Clp protease adaptor protein ClpS YP_001235950.1 PFAM: GCN5-related N-acetyltransferase YP_001235951.1 PFAM: Cold-shock protein, DNA-binding; Ribonuclease B, OB region N-terminal domain; SMART: Cold shock protein YP_001235953.1 involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function YP_001235955.1 TIGRFAM: 40-residue YVTN family beta-propeller repeat protein YP_001235956.1 PFAM: O-antigen polymerase YP_001235957.1 PFAM: Methyltransferase type 11; Methyltransferase type 12 YP_001235958.1 PFAM: alpha/beta hydrolase fold; PGAP1 family protein YP_001235959.1 PFAM: protein of unknown function DUF55 YP_001235960.1 PFAM: YCII-related YP_001235961.1 TIGRFAM: heme exporter protein CcmC; PFAM: cytochrome c assembly protein YP_001235962.1 CycJ; periplasmic heme chaperone that binds heme transiently via a histidine residue and delivers it to newly synthesized and exported c-type cytochromes; requires the ATP hydrolysis activity of the CcmA protein in order to transfer the heme to the apocytochrome; part of the cytochrome c maturation system; periplasmic protein anchored to the inner membrane YP_001235963.1 PFAM: cytochrome c assembly protein YP_001235964.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; Thioredoxin domain YP_001235965.1 PFAM: cytochrome C biogenesis protein YP_001235967.1 PFAM: protein of unknown function DUF1674 YP_001235968.1 PFAM: Cl- channel, voltage-gated family protein YP_001235969.1 thiamine-pyrophosphate requiring enzyme YP_001235971.1 PFAM: OmpA/MotB domain protein YP_001235972.1 TIGRFAM: ATP-dependent helicase HrpB; PFAM: helicase domain protein; helicase-associated domain protein; Helicase ATP-dependent, C-terminal domain protein; SMART: DEAD-like helicases-like YP_001235973.1 PFAM: cytochrome c biogenesis protein, transmembrane region YP_001235974.1 PFAM: cytochrome c, class I YP_001235976.1 PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein YP_001235978.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001235979.1 PFAM: protein of unknown function DUF140 YP_001235980.1 TIGRFAM: alanine racemase; PFAM: alanine racemase domain protein YP_001235982.1 unwinds double stranded DNA YP_001235985.1 PFAM: RbsD or FucU transport YP_001235986.1 PFAM: PfkB domain protein YP_001235987.1 TIGRFAM: ammonium transporter; PFAM: Rh family protein/ammonium transporter YP_001235989.1 PFAM: CBS domain containing protein YP_001235990.1 TIGRFAM: pyridoxal kinase; PFAM: Phosphomethylpyrimidine kinase type-1 YP_001235991.1 PFAM: NADH:flavin oxidoreductase/NADH oxidase YP_001235992.1 Represses a number of genes involved in the response to DNA damage YP_001235993.1 PFAM: heat shock protein DnaJ domain protein YP_001235994.1 PFAM: Peptidoglycan-binding domain 1 protein; N-acetylmuramoyl-L-alanine amidase, family 2 YP_001235995.1 TIGRFAM: DNA gyrase, B subunit; PFAM: DNA gyrase, subunit B domain protein; ATP-binding region, ATPase domain protein; TOPRIM domain protein; DNA topoisomerase, type IIA, subunit B, region 2 domain protein; SMART: DNA topoisomerase II YP_001235997.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001235998.1 PFAM: Auxin Efflux Carrier YP_001235999.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein YP_001236001.1 PFAM: glutathione-dependent formaldehyde-activating, GFA YP_001236003.1 PFAM: helix-turn-helix domain protein YP_001236004.1 PFAM: Smr protein/MutS2 YP_001236005.1 PFAM: protein of unknown function DUF162 YP_001236006.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; protein of unknown function DUF162 YP_001236007.1 PFAM: Lytic transglycosylase, catalytic YP_001236008.1 PFAM: TolB, N-terminal domain protein; WD40 domain protein beta Propeller YP_001236010.1 PFAM: Biopolymer transport protein ExbD/TolR YP_001236011.1 PFAM: MotA/TolQ/ExbB proton channel YP_001236012.1 PFAM: thioesterase superfamily protein YP_001236013.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration YP_001236014.1 plays an essential role in ATP-dependent branch migration of the Holliday junction YP_001236015.1 endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity YP_001236016.1 PFAM: protein of unknown function DUF28 YP_001236017.1 PFAM: glycosyl transferase, group 1 YP_001236018.1 PFAM: glycosyl transferase, group 1 YP_001236019.1 PFAM: major facilitator superfamily MFS_1 YP_001236021.1 PFAM: phosphonate metabolism YP_001236022.1 PFAM: phosphonate metabolism YP_001236023.1 PFAM: phosphonate metabolism PhnJ YP_001236024.1 TIGRFAM: phosphonate C-P lyase system protein PhnK; PFAM: ABC transporter related; SMART: AAA ATPase YP_001236025.1 TIGRFAM: phosphonate C-P lyase system protein PhnL; PFAM: ABC transporter related; SMART: AAA ATPase YP_001236026.1 TIGRFAM: phosphonate metabolism protein PhnM; PFAM: amidohydrolase; Amidohydrolase 3 YP_001236027.1 PFAM: protein of unknown function DUF1045 YP_001236028.1 TIGRFAM: phosphonate metabolism protein/1,5-bisphosphokinase (PRPP-forming) PhnN; SMART: guanylate kinase/L-type calcium channel region YP_001236029.1 TIGRFAM: phosphonates metabolism transcriptional regulator PhnF; PFAM: regulatory protein GntR, HTH; UbiC transcription regulator-associated domain protein YP_001236030.1 PFAM: glycosyl transferase, family 2 YP_001236031.1 PFAM: ribosomal protein L35 YP_001236032.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit YP_001236033.1 PFAM: glycosyl transferase, group 1 YP_001236034.1 PFAM: metallophosphoesterase YP_001236035.1 PFAM: protein of unknown function DUF1486 YP_001236036.1 PFAM: Alcohol dehydrogenase, zinc-binding domain protein YP_001236037.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001236038.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001236040.1 PFAM: inner-membrane translocator YP_001236041.1 PFAM: inner-membrane translocator YP_001236042.1 PFAM: Amidase YP_001236043.1 PFAM: alpha amylase, catalytic region; SMART: alpha amylase, catalytic sub domain YP_001236044.1 TIGRFAM: trehalose synthase; trehalose synthase-fused possible maltokinase; PFAM: alpha amylase, catalytic region; SMART: alpha amylase, catalytic sub domain YP_001236045.1 TIGRFAM: 1,4-alpha-glucan branching enzyme; PFAM: glycoside hydrolase, family 13 domain protein; alpha amylase, catalytic region; alpha amylase, C-terminal all-beta; SMART: alpha amylase, catalytic sub domain YP_001236046.1 TIGRFAM: glycogen debranching enzyme GlgX; PFAM: glycoside hydrolase, family 13 domain protein; alpha amylase, catalytic region; SMART: alpha amylase, catalytic sub domain YP_001236047.1 TIGRFAM: 4-alpha-glucanotransferase; PFAM: glycoside hydrolase, family 77 YP_001236049.1 PFAM: glycosyl transferase, family 2 YP_001236050.1 PFAM: glycosyl transferase, group 1 YP_001236051.1 TIGRFAM: methyltransferase FkbM family YP_001236053.1 catalyzes the conversion of the propionic acid groups of rings I and III to vinyl groups during heme synthesis YP_001236054.1 PFAM: Cytochrome b/b6, N-terminal domain YP_001236055.1 PFAM: cytochrome c1 YP_001236056.1 Catalyzes the reversible phosphorolysis of 5'-deoxy-5'- methylthioadenosine (MTA) to adenine and 5-methylthio-D-ribose-1- phosphate YP_001236057.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein YP_001236058.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation YP_001236059.1 TIGRFAM: phosphate transport system regulatory protein PhoU; PFAM: PhoU family protein YP_001236060.1 TIGRFAM: phosphate regulon transcriptional regulatory protein PhoB; PFAM: response regulator receiver; transcriptional regulator domain protein YP_001236062.1 PFAM: Na+/solute symporter YP_001236063.1 PFAM: protein of unknown function DUF1275 YP_001236065.1 PFAM: sugar transferase YP_001236066.1 TIGRFAM: histidine kinase; PFAM: ATP-binding region, ATPase domain protein; histidine kinase A domain protein YP_001236067.1 PFAM: response regulator receiver; sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; SMART: AAA ATPase YP_001236068.1 PFAM: Tetratricopeptide TPR_4; SMART: Tetratricopeptide domain protein YP_001236069.1 PFAM: O-antigen polymerase YP_001236071.1 PFAM: glycosyl transferase, group 1 YP_001236072.1 PFAM: polysaccharide export protein YP_001236073.1 PFAM: lipopolysaccharide biosynthesis protein YP_001236076.1 SMART: AAA ATPase YP_001236077.1 PFAM: polysaccharide deacetylase YP_001236080.1 TIGRFAM: eight transmembrane protein EpsH YP_001236083.1 PFAM: Cupin 2, conserved barrel domain protein YP_001236084.1 PFAM: sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; GAF domain protein; SMART: AAA ATPase YP_001236085.1 PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein YP_001236087.1 PFAM: TadE family protein YP_001236088.1 PFAM: TadE family protein YP_001236090.1 TIGRFAM: L-rhamnose 1-epimerase; PFAM: protein of unknown function DUF718 YP_001236091.1 PFAM: inner-membrane translocator YP_001236092.1 PFAM: inner-membrane translocator YP_001236093.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001236095.1 PFAM: regulatory protein, DeoR YP_001236096.1 TIGRFAM: L-rhamnose isomerase; PFAM: Xylose isomerase domain protein TIM barrel YP_001236097.1 TIGRFAM: rhamnulose-1-phosphate aldolase/alcohol dehydrogenase; PFAM: class II aldolase/adducin family protein; short-chain dehydrogenase/reductase SDR; KR YP_001236098.1 PFAM: carbohydrate kinase, FGGY YP_001236099.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; Cache, type 2 domain protein YP_001236100.1 PFAM: Cold-shock protein, DNA-binding; SMART: Cold shock protein YP_001236101.1 PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein YP_001236103.1 PFAM: oxidoreductase, molybdopterin binding YP_001236106.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein YP_001236107.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001236108.1 TIGRFAM: alkylhydroperoxidase like protein, AhpD family; uncharacterized peroxidase-related enzyme; PFAM: Carboxymuconolactone decarboxylase YP_001236109.1 PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase YP_001236110.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001236111.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001236112.1 PFAM: extracellular solute-binding protein, family 1 YP_001236113.1 TIGRFAM: 4-carboxymuconolactone decarboxylase; 3-oxoadipate enol-lactonase; PFAM: alpha/beta hydrolase fold; Carboxymuconolactone decarboxylase; Ndr family protein YP_001236114.1 PFAM: aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding YP_001236115.1 PFAM: ferredoxin; [2Fe-2S]-binding domain protein YP_001236116.1 PFAM: regulatory protein, MarR YP_001236117.1 TIGRFAM: L-2,4-diaminobutyric acid acetyltransferase; PFAM: GCN5-related N-acetyltransferase YP_001236118.1 catalyzes the reversible formation of diaminobutyrate and 2-oxoglutarate from glutamate and L-aspartic beta-semialdehyde YP_001236119.1 N-acetyldiaminobutyrate dehydratase; catalyzes the formation of the osmoprotectant ecotoine from gamma-N-acetyl-alpha,gamma-diaminobutyric acid YP_001236120.1 TIGRFAM: ectoine hydroxylase; PFAM: Phytanoyl-CoA dioxygenase YP_001236121.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP YP_001236122.1 PFAM: major facilitator superfamily MFS_1 YP_001236124.1 PFAM: Mammalian cell entry related domain protein YP_001236125.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001236126.1 PFAM: protein of unknown function DUF140 YP_001236127.1 PFAM: Integral membrane protein TerC YP_001236128.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide YP_001236129.1 PFAM: protein of unknown function DUF833 YP_001236130.1 TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: aldehyde dehydrogenase YP_001236131.1 TIGRFAM: amidase, hydantoinase/carbamoylase family; PFAM: peptidase M20; peptidase dimerisation domain protein YP_001236136.1 TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; cadmium-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: Haloacid dehalogenase domain protein hydrolase; E1-E2 ATPase-associated domain protein YP_001236139.1 PFAM: alpha/beta hydrolase fold; Poly-beta-hydroxybutyrate polymerase domain protein YP_001236140.1 PFAM: phosphate acetyl/butaryl transferase; MaoC domain protein dehydratase YP_001236141.1 TIGRFAM: alkylhydroperoxidase like protein, AhpD family; PFAM: Carboxymuconolactone decarboxylase YP_001236142.1 PFAM: peptidase A24A, prepilin type IV YP_001236143.1 PFAM: permease for cytosine/purines, uracil, thiamine, allantoin YP_001236146.1 PFAM: regulatory protein, TetR YP_001236147.1 PFAM: class II aldolase/adducin family protein YP_001236149.1 PFAM: oxidoreductase, molybdopterin binding; Mo-co oxidoreductase dimerisation domain YP_001236150.1 PFAM: cytochrome c, class I YP_001236151.1 PFAM: cytochrome c, class I YP_001236156.1 PFAM: metallophosphoesterase; 5'-Nucleotidase domain protein YP_001236158.1 PFAM: protein of unknown function DUF81 YP_001236159.1 PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_4 YP_001236161.1 PFAM: protein of unknown function DUF302 YP_001236162.1 PFAM: phosphoesterase YP_001236163.1 TIGRFAM: acetate kinase; PFAM: acetate and butyrate kinase YP_001236164.1 PFAM: Forkhead-associated protein YP_001236165.1 TIGRFAM: glutamine synthetase, type I; PFAM: glutamine synthetase, catalytic region; glutamine synthetase, beta-Grasp YP_001236166.1 PFAM: nitrogen regulatory protein P-II YP_001236167.1 PFAM: aminotransferase, class V; aminotransferase, class I and II YP_001236168.1 PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase YP_001236169.1 PFAM: ATP-NAD/AcoX kinase YP_001236170.1 PFAM: protein of unknown function UPF0157 YP_001236171.1 catalyzes the oxidation of malate to oxaloacetate YP_001236174.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001236175.1 PFAM: protein of unknown function DUF796 YP_001236176.1 PFAM: AAA ATPase, central domain protein; Clp N terminal domain protein; ATPase associated with various cellular activities, AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase YP_001236177.1 PFAM: ImpA domain protein YP_001236178.1 PFAM: protein of unknown function DUF877 YP_001236179.1 PFAM: protein of unknown function DUF877 YP_001236180.1 PFAM: uncharacterised conserved protein UCP028301 YP_001236181.1 PFAM: virulence protein, SciE type YP_001236182.1 PFAM: GPW/gp25 family protein YP_001236183.1 PFAM: protein of unknown function DUF879 YP_001236184.1 PFAM: protein of unknown function DUF1305 YP_001236185.1 PFAM: Methyltransferase type 11; Methyltransferase type 12 YP_001236188.1 PFAM: phospholipid/glycerol acyltransferase YP_001236189.1 PFAM: protein of unknown function DUF218 YP_001236190.1 PFAM: protein of unknown function DUF214 YP_001236191.1 TIGRFAM: cell division ATP-binding protein FtsE; PFAM: ABC transporter related; SMART: AAA ATPase YP_001236192.1 TIGRFAM: MJ0042 family finger-like protein YP_001236193.1 PFAM: peptidase M19, renal dipeptidase YP_001236194.1 molecular chaperone YP_001236195.1 PFAM: helicase domain protein YP_001236196.1 PFAM: RNA-binding S4 domain protein YP_001236197.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001236198.1 PFAM: transcription factor CarD YP_001236199.1 TIGRFAM: Mn2+/Fe2+ transporter, NRAMP family; PFAM: natural resistance-associated macrophage protein YP_001236200.1 PFAM: ABC transporter related YP_001236201.1 PFAM: inner-membrane translocator; ABC transporter related; SMART: AAA ATPase YP_001236202.1 PFAM: inner-membrane translocator YP_001236203.1 PFAM: Extracellular ligand-binding receptor YP_001236204.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug YP_001236205.1 TIGRFAM: haloacid dehalogenase, type II; HAD-superfamily hydrolase, subfamily IA, variant 2 (HAD-like); PFAM: Haloacid dehalogenase domain protein hydrolase YP_001236206.1 PFAM: Glutathione S-transferase, N-terminal domain YP_001236208.1 PFAM: regulatory protein, TetR YP_001236210.1 TIGRFAM: O-succinylhomoserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes; aromatic amino acid beta-eliminating lyase/threonine aldolase YP_001236211.1 PFAM: ribosomal protein S20