-- dump date   	20140618_183904
-- class       	Genbank::misc_feature
-- table       	misc_feature_note
-- id	note
634456000001	Transposase; Region: HTH_Tnp_1; pfam01527
634456000002	UvrD/REP helicase N-terminal domain; Region: UvrD-helicase; pfam00580
634456000003	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
634456000004	Transposase; Region: DEDD_Tnp_IS110; pfam01548
634456000005	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
634456000006	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
634456000007	Transposase; Region: DEDD_Tnp_IS110; pfam01548
634456000008	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
634456000009	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
634456000010	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
634456000011	catalytic residues [active]
634456000012	catalytic nucleophile [active]
634456000013	Presynaptic Site I dimer interface [polypeptide binding]; other site
634456000014	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
634456000015	Synaptic Flat tetramer interface [polypeptide binding]; other site
634456000016	Synaptic Site I dimer interface [polypeptide binding]; other site
634456000017	DDE superfamily endonuclease; Region: DDE_4; cl17710
634456000018	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
634456000019	Mannitol-1-phosphate/altronate dehydrogenases [Carbohydrate transport and metabolism]; Region: MtlD; COG0246
634456000020	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
634456000021	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
634456000022	haloacid dehalogenase-like hydrolase; Region: Hydrolase; pfam00702
634456000023	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
634456000024	motif II; other site
634456000025	Hypothetical protein (DUF2513); Region: DUF2513; pfam10711
634456000026	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
634456000027	Walker A/P-loop; other site
634456000028	ATP binding site [chemical binding]; other site
634456000029	Superfamily I DNA and RNA helicases and helicase subunits [DNA replication, recombination, and repair]; Region: COG1112
634456000030	AAA domain; Region: AAA_12; pfam13087
634456000031	C-terminal domain of Escherichia coli uncharacterized protein yjhR and similar proteins; Region: PLDc_yjhR_C_like; cd09118
634456000032	PLD-like domain; Region: PLDc_2; pfam13091
634456000033	putative active site [active]
634456000034	catalytic site [active]
634456000035	Transposase DDE domain group 1; Region: DDE_Tnp_1_4; pfam13701
634456000036	Transposase DDE domain group 1; Region: DDE_Tnp_1_4; pfam13701
634456000037	Domain Homologous to E6-AP Carboxyl Terminus with; Region: HECTc; smart00119
634456000038	Transposase; Region: HTH_Tnp_1; pfam01527
634456000039	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: Tra5; COG2801
634456000040	HTH-like domain; Region: HTH_21; pfam13276
634456000041	Integrase core domain; Region: rve; pfam00665
634456000042	Integrase core domain; Region: rve_3; pfam13683
634456000043	conjugal transfer/type IV secretion protein DotA/TraY; Region: DotA_TraY; TIGR04346
634456000044	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
634456000045	Transposase DDE domain group 1; Region: DDE_Tnp_1_4; pfam13701
634456000046	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
634456000047	DNA binding site [nucleotide binding]
634456000048	Int/Topo IB signature motif; other site
634456000049	active site
634456000050	Plasmid encoded RepA protein; Region: RepA_C; pfam04796
634456000051	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
634456000052	non-specific DNA binding site [nucleotide binding]; other site
634456000053	salt bridge; other site
634456000054	sequence-specific DNA binding site [nucleotide binding]; other site
634456000055	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
634456000056	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
634456000057	P-loop; other site
634456000058	Magnesium ion binding site [ion binding]; other site
634456000059	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
634456000060	Magnesium ion binding site [ion binding]; other site
634456000061	ParB-like nuclease domain; Region: ParBc; pfam02195
634456000062	KorB domain; Region: KorB; pfam08535
634456000063	Adenine-specific DNA methylase [DNA replication, recombination, and repair]; Region: COG0827
634456000064	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
634456000065	S-adenosylmethionine binding site [chemical binding]; other site
634456000066	DNA methylase [Transcription / DNA replication, recombination, and repair]; Region: COG4646
634456000067	Transposase DDE domain; Region: DDE_Tnp_1_5; pfam13737
634456000068	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
634456000069	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
634456000070	IHF dimer interface [polypeptide binding]; other site
634456000071	IHF - DNA interface [nucleotide binding]; other site
634456000072	TrwC relaxase; Region: TrwC; pfam08751
634456000073	Transposase DDE domain group 1; Region: DDE_Tnp_1_4; pfam13701
634456000074	Transposase DDE domain group 1; Region: DDE_Tnp_1_4; pfam13701
634456000075	Transposase DDE domain group 1; Region: DDE_Tnp_1_4; pfam13701
634456000076	Transposase domain (DUF772); Region: DUF772; pfam05598
634456000077	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
634456000078	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
634456000079	Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family [Energy production and conversion]; Region: COG1979
634456000080	Butanol dehydrogenase catalyzes the conversion of butyraldehyde to butanol with the cofactor NAD(P)H being oxidized in the process; Region: BDH; cd08187
634456000081	dimer interface [polypeptide binding]; other site
634456000082	active site
634456000083	metal binding site [ion binding]; metal-binding site
634456000084	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
634456000085	Mycobacterium tuberculosis succinate-semialdehyde dehydrogenase 1-like; Region: ALDH_SSADH1_GabD1; cd07100
634456000086	NAD(P) binding site [chemical binding]; other site
634456000087	catalytic residues [active]
634456000088	Integrase core domain; Region: rve; pfam00665
634456000089	Winged helix-turn helix; Region: HTH_29; pfam13551
634456000090	Integrase core domain; Region: rve; pfam00665
634456000091	FOG: Transposase [DNA replication, recombination, and repair]; Region: COG5659
634456000092	Outer membrane protein family (DUF1597); Region: DUF1597; pfam07642
634456000093	potassium-transporting ATPase subunit A; Provisional; Region: PRK05482
634456000094	potassium-transporting ATPase subunit B; Provisional; Region: PRK01122
634456000095	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
634456000096	haloacid dehalogenase-like hydrolase; Region: HAD; pfam12710
634456000097	Soluble P-type ATPase [General function prediction only]; Region: COG4087
634456000098	potassium-transporting ATPase subunit C; Provisional; Region: PRK13999
634456000099	Osmosensitive K+ channel histidine kinase [Signal transduction mechanisms]; Region: KdpD; COG2205
634456000100	Osmosensitive K+ channel His kinase sensor domain; Region: KdpD; pfam02702
634456000101	USP domain is located between the N-terminal sensor domain and C-terminal catalytic domain of this Osmosensitive K+ channel histidine kinase family. The family of KdpD sensor kinase proteins regulates the kdpFABC operon responsible for potassium...; Region: USP_OKCHK; cd01987
634456000102	Ligand Binding Site [chemical binding]; other site
634456000103	Domain of unknown function (DUF4118); Region: DUF4118; pfam13493
634456000104	GAF domain; Region: GAF_3; pfam13492
634456000105	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
634456000106	dimer interface [polypeptide binding]; other site
634456000107	phosphorylation site [posttranslational modification]
634456000108	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
634456000109	ATP binding site [chemical binding]; other site
634456000110	Mg2+ binding site [ion binding]; other site
634456000111	G-X-G motif; other site
634456000112	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
634456000113	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
634456000114	active site
634456000115	phosphorylation site [posttranslational modification]
634456000116	intermolecular recognition site; other site
634456000117	dimerization interface [polypeptide binding]; other site
634456000118	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
634456000119	DNA binding site [nucleotide binding]
634456000120	NhaP-type Na+/H+ and K+/H+ antiporters [Inorganic ion transport and metabolism]; Region: NhaP; COG0025
634456000121	Transposase DDE domain group 1; Region: DDE_Tnp_1_4; pfam13701
634456000122	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
634456000123	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
634456000124	Sulfotransferase domain; Region: Sulfotransfer_1; pfam00685
634456000125	Acyltransferase family; Region: Acyl_transf_3; pfam01757
634456000126	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cl17220
634456000127	Fic/DOC family; Region: Fic; cl00960
634456000128	Replication protein C N-terminal domain; Region: RP-C; pfam03428
634456000129	Replication protein C C-terminal region; Region: RP-C_C; pfam11800
634456000130	Transposase DDE domain group 1; Region: DDE_Tnp_1_4; pfam13701
634456000131	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
634456000132	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
634456000133	glycerophosphodiester phosphodiesterase; Provisional; Region: glpQ; PRK11143
634456000134	Catalytic domain of phosphoinositide-specific phospholipase C-like phosphodiesterases superfamily; Region: PI-PLCc_GDPD_SF; cl14615
634456000135	active site
634456000136	catalytic site [active]
634456000137	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
634456000138	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
634456000139	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
634456000140	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
634456000141	CrcB-like protein; Region: CRCB; cl09114
634456000142	Transposase DDE domain group 1; Region: DDE_Tnp_1_4; pfam13701
634456000143	Transposase DDE domain; Region: DDE_Tnp_1_5; pfam13737
634456000144	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
634456000145	Transposase DDE domain group 1; Region: DDE_Tnp_1_4; pfam13701
634456000146	Transposase domain (DUF772); Region: DUF772; pfam05598
634456000147	Antidote-toxin recognition MazE; Region: Antitoxin-MazE; cl00877
634456000148	Regulators of stationary/sporulation gene expression [Transcription]; Region: AbrB; COG2002
634456000149	Toxin with endonuclease activity YhaV; Region: Toxin_YhaV; pfam11663
634456000150	Transposase DDE domain group 1; Region: DDE_Tnp_1_4; pfam13701
634456000151	Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; pfam13340
634456000152	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
634456000153	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
634456000154	manganese transport protein MntH; Reviewed; Region: PRK00701
634456000155	Natural resistance-associated macrophage protein; Region: Nramp; pfam01566
634456000156	manganese transport regulator MntR; Provisional; Region: PRK11050
634456000157	Iron dependent repressor, N-terminal DNA binding domain; Region: Fe_dep_repress; pfam01325
634456000158	Iron dependent repressor, metal binding and dimerisation domain; Region: Fe_dep_repr_C; pfam02742
634456000159	ABC-type uncharacterized transport system, permease and ATPase components [General function prediction only]; Region: COG4178
634456000160	ABC transporter transmembrane region 2; Region: ABC_membrane_2; cl00549
634456000161	ATP-binding cassette domain of peroxisomal transporter, subfamily D; Region: ABCD_peroxisomal_ALDP; cd03223
634456000162	Carbohydrate-selective porin, OprB family; Region: OprB; pfam04966
634456000163	Probable cobalt transporter subunit (CbtB); Region: CbtB; cl09723
634456000164	Probable cobalt transporter subunit (CbtA); Region: CbtA; cl02266
634456000165	Rieske domain; a [2Fe-2S] cluster binding domain commonly found in Rieske non-heme iron oxygenase (RO) systems such as naphthalene and biphenyl dioxygenases, as well as in plant/cyanobacterial chloroplast b6f and mitochondrial cytochrome bc(1) complexes; Region: Rieske; cl00938
634456000166	Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit [Inorganic ion transport and metabolism / General function prediction only]; Region: HcaE; COG4638
634456000167	iron-sulfur cluster [ion binding]; other site
634456000168	[2Fe-2S] cluster binding site [ion binding]; other site
634456000169	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
634456000170	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
634456000171	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
634456000172	Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; pfam13340
634456000173	FOG: Transposase [DNA replication, recombination, and repair]; Region: COG5659
634456000174	Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; pfam13340
634456000175	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
634456000176	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
634456000177	putative transposase OrfB; Reviewed; Region: PHA02517
634456000178	HTH-like domain; Region: HTH_21; pfam13276
634456000179	Integrase core domain; Region: rve; pfam00665
634456000180	Integrase core domain; Region: rve_3; pfam13683
634456000181	Transposase; Region: HTH_Tnp_1; cl17663
634456000182	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cd00312
634456000183	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
634456000184	Transposase domain (DUF772); Region: DUF772; pfam05598
634456000185	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
634456000186	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
634456000187	CRISPR/Cas system-associated protein Cas3'' Region: Cas3''_I; cd09641
634456000188	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
634456000189	CRISPR-associated helicase Cas3; Region: cas3_core; TIGR01587
634456000190	CRISPR/Cas system-associated protein Cse1; Region: Cse1_I-E; cd09729
634456000191	CRISPR-associated protein Cse2 (CRISPR_cse2); Region: CRISPR_Cse2; pfam09485
634456000192	CRISPR/Cas system-associated RAMP superfamily protein Cas7; Region: Cas7_I-E; cl09608
634456000193	CRISPR-associated protein (Cas_Cas5); Region: Cas_Cas5d; pfam09704
634456000194	CRISPR/Cas system-associated RAMP superfamily protein Cas5; Region: Cas5_I; cd09693
634456000195	CRISPR/Cas system-associated RAMP superfamily protein Cas6e; Region: Cas6_I-E; cd09727
634456000196	CRISPR/Cas system-associated protein Cas1; Region: Cas1_I-II-III; cl00656
634456000197	CRISPR/Cas system-associated protein Cas2; Region: Cas2_I-E; cd09648
634456000198	Winged helix-turn helix; Region: HTH_29; pfam13551
634456000199	Integrase core domain; Region: rve; pfam00665
634456000200	Integrase core domain; Region: rve_3; pfam13683
634456000201	Predicted transcriptional regulator [Transcription]; Region: COG4190
634456000202	Abi-like protein; Region: Abi_2; pfam07751
634456000203	putative transposase OrfB; Reviewed; Region: PHA02517
634456000204	HTH-like domain; Region: HTH_21; pfam13276
634456000205	Integrase core domain; Region: rve; pfam00665
634456000206	Integrase core domain; Region: rve_3; pfam13683
634456000207	Transposase; Region: HTH_Tnp_1; cl17663
634456000208	Predicted membrane protein [Function unknown]; Region: COG3431
634456000209	Transposase DDE domain group 1; Region: DDE_Tnp_1_4; pfam13701
634456000210	Truncated hemoglobins (trHbs) are a family of oxygen-binding heme proteins found in cyanobacteria, eubacteria, unicellular eukaryotes, and plants. The truncated hemoglobins have a characteristic two-over-two alpha helical folding pattern that is distinct...; Region: Trunc_globin; cd00454
634456000211	apolar tunnel; other site
634456000212	heme binding site [chemical binding]; other site
634456000213	dimerization interface [polypeptide binding]; other site
634456000214	Domain of unknown function (DUF1971); Region: DUF1971; pfam09313
634456000215	Transposase domain (DUF772); Region: DUF772; pfam05598
634456000216	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
634456000217	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
634456000218	HTH-like domain; Region: HTH_21; pfam13276
634456000219	Integrase core domain; Region: rve; pfam00665
634456000220	Integrase core domain; Region: rve_3; pfam13683
634456000221	Transposase; Region: HTH_Tnp_1; pfam01527
634456000222	bifunctional antitoxin/transcriptional repressor RelB; Provisional; Region: PRK11235
634456000223	Cytotoxic translational repressor of toxin-antitoxin stability system [Translation, ribosomal structure and biogenesis / Cell division and chromosome partitioning]; Region: RelE; COG2026
634456000224	Abi-like protein; Region: Abi_2; cl01988
634456000225	myosin-cross-reactive antigen; Provisional; Region: PRK13977
634456000226	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
634456000227	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
634456000228	Transposase DDE domain group 1; Region: DDE_Tnp_1_4; pfam13701
634456000229	Transposase domain (DUF772); Region: DUF772; pfam05598
634456000230	Phosphate-selective porin O and P; Region: Porin_O_P; pfam07396
634456000231	Transposase DDE domain group 1; Region: DDE_Tnp_1_4; pfam13701
634456000232	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
634456000233	TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; Region: TonB-hemlactrns; TIGR01786
634456000234	DNA polymerase III subunits gamma and tau; Provisional; Region: PRK14971
634456000235	FOG: Transposase [DNA replication, recombination, and repair]; Region: COG5659
634456000236	Transposase domain (DUF772); Region: DUF772; pfam05598
634456000237	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
634456000238	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
634456000239	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
634456000240	IHF dimer interface [polypeptide binding]; other site
634456000241	IHF - DNA interface [nucleotide binding]; other site
634456000242	putative transposase OrfB; Reviewed; Region: PHA02517
634456000243	HTH-like domain; Region: HTH_21; pfam13276
634456000244	Integrase core domain; Region: rve; pfam00665
634456000245	Integrase core domain; Region: rve_3; pfam13683
634456000246	Transposase; Region: HTH_Tnp_1; cl17663
634456000247	PemK-like protein; Region: PemK; cl00995
634456000248	Growth regulator [Signal transduction mechanisms]; Region: MazE; COG2336
634456000249	PIN domain of ribonucleases (toxins), VapC and FitB, of prokaryotic toxin/antitoxin operons, Pyrococcus horikoshii protein PH0500, and other similar bacterial and archaeal homologs; Region: PIN_VapC-FitB; cd09881
634456000250	oligomeric interface; other site
634456000251	putative active site [active]
634456000252	homodimer interface [polypeptide binding]; other site
634456000253	Virulence-associated protein and related proteins [Function unknown]; Region: VagC; COG4456
634456000254	Integrase core domain; Region: rve_3; pfam13683
634456000255	Transposase DDE domain group 1; Region: DDE_Tnp_1_4; pfam13701
634456000256	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
634456000257	DNA-binding interface [nucleotide binding]; DNA binding site
634456000258	hypothetical protein; Provisional; Region: PRK10621
634456000259	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
634456000260	DDE superfamily endonuclease; Region: DDE_5; pfam13546
634456000261	Transposase DDE domain group 1; Region: DDE_Tnp_1_4; pfam13701
634456000262	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
634456000263	active site
634456000264	propionyl-CoA synthetase; Provisional; Region: prpE; PRK10524
634456000265	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
634456000266	acyl-activating enzyme (AAE) consensus motif; other site
634456000267	AMP binding site [chemical binding]; other site
634456000268	active site
634456000269	CoA binding site [chemical binding]; other site
634456000270	flavin-dependent oxidoreductase, MSMEG_0569 family; Region: MSMEG_0569_nitr; TIGR04046
634456000271	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
634456000272	glycosyltransferase, MSMEG_0565 family; Region: MSMEG_0565_glyc; TIGR04047
634456000273	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
634456000274	AIR synthase-related protein, sll0787 family; Region: AIR_rel_sll0787; TIGR04049
634456000275	AIR synthase (PurM) related protein, subgroup 3 of unknown function. The family of PurM related proteins includes Hydrogen expression/formation protein HypE, AIR synthases, FGAM synthase and Selenophosphate synthetase (SelD). They all contain two...; Region: PurM-like3; cd02192
634456000276	dimerization interface [polypeptide binding]; other site
634456000277	putative ATP binding site [chemical binding]; other site
634456000278	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
634456000279	Coenzyme A binding pocket [chemical binding]; other site
634456000280	radical SAM protein, MSMEG_0568 family; Region: rSAM_MSMEG_0568; TIGR04043
634456000281	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
634456000282	FeS/SAM binding site; other site
634456000283	Predicted amidohydrolase [General function prediction only]; Region: COG0388
634456000284	Nitrilases, cyanide hydratase (CH)s, and similar proteins (class 1 nitrilases); Region: nitrilases_CHs; cd07564
634456000285	putative active site [active]
634456000286	catalytic triad [active]
634456000287	putative dimer interface [polypeptide binding]; other site
634456000288	MSMEG_0572 family protein; Region: MSMEG_0572_fam; TIGR04044
634456000289	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
634456000290	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
634456000291	DNA-binding site [nucleotide binding]; DNA binding site
634456000292	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
634456000293	pyridoxal 5'-phosphate binding site [chemical binding]; other site
634456000294	homodimer interface [polypeptide binding]; other site
634456000295	catalytic residue [active]
634456000296	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
634456000297	Transcriptional regulator [Transcription]; Region: LysR; COG0583
634456000298	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
634456000299	The C-terminal substrate binding domain of LysR-type transcriptional regulators involved in the catabolism of aromatic compounds and that of other related regulators, contains type 2 periplasmic binding fold; Region: PBP2_LTTR_aromatics_like; cd08414
634456000300	dimerization interface [polypeptide binding]; other site
634456000301	substrate binding pocket [chemical binding]; other site
634456000302	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
634456000303	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
634456000304	putative substrate translocation pore; other site
634456000305	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
634456000306	Transposase DDE domain group 1; Region: DDE_Tnp_1_4; pfam13701
634456000307	Transposase DDE domain group 1; Region: DDE_Tnp_1_4; pfam13701
634456000308	UvrD-like helicase C-terminal domain; Region: UvrD_C; pfam13361
634456000309	helicase, putative, RecD/TraA family; Region: recD_rel; TIGR01448
634456000310	AAA domain; Region: AAA_30; pfam13604
634456000311	Family description; Region: UvrD_C_2; pfam13538
634456000312	DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182
634456000313	active site
634456000314	catalytic residues [active]
634456000315	DNA binding site [nucleotide binding]
634456000316	Int/Topo IB signature motif; other site
634456000317	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
634456000318	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
634456000319	Transposase DDE domain group 1; Region: DDE_Tnp_1_4; pfam13701
634456000320	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases [Defense mechanisms]; Region: COG0610
634456000321	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; pfam04313
634456000322	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
634456000323	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
634456000324	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
634456000325	Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; pfam13340
634456000326	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
634456000327	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
634456000328	Nucleotidyltransferase (NT) domain of Staphylococcus aureus kanamycin nucleotidyltransferase, and similar proteins; Region: NT_KNTase_like; cd05403
634456000329	active site
634456000330	NTP binding site [chemical binding]; other site
634456000331	metal binding triad [ion binding]; metal-binding site
634456000332	antibiotic binding site [chemical binding]; other site
634456000333	Nucleotidyltransferase substrate binding protein like; Region: NTase_sub_bind; pfam08780
634456000334	HsdM N-terminal domain; Region: HsdM_N; pfam12161
634456000335	N-6 DNA Methylase; Region: N6_Mtase; pfam02384
634456000336	Methyltransferase domain; Region: Methyltransf_26; pfam13659
634456000337	S-adenosylmethionine binding site [chemical binding]; other site
634456000338	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
634456000339	Old yellow enzyme (OYE)-like FMN binding domain. OYE was the first flavin-dependent enzyme identified, however its true physiological role remains elusive to this day. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a...; Region: OYE_like_FMN; cd02933
634456000340	FMN binding site [chemical binding]; other site
634456000341	active site
634456000342	substrate binding site [chemical binding]; other site
634456000343	catalytic residue [active]
634456000344	FOG: Transposase [DNA replication, recombination, and repair]; Region: COG5659
634456000345	Outer membrane protein family (DUF1597); Region: DUF1597; pfam07642
634456000346	Transposase DDE domain group 1; Region: DDE_Tnp_1_4; pfam13701
634456000347	Transcriptional regulator [Transcription]; Region: LysR; COG0583
634456000348	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
634456000349	The C-terminal substrate-binding domain of putative LysR-type transcriptional regulator PAO1-like, a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_PAO1_like; cd08412
634456000350	putative substrate binding pocket [chemical binding]; other site
634456000351	dimerization interface [polypeptide binding]; other site
634456000352	acetylornithine deacetylase; Provisional; Region: PRK07522
634456000353	M20 Peptidase acetylornithine deacetylase; Region: M20_ArgE; cd03894
634456000354	metal binding site [ion binding]; metal-binding site
634456000355	putative dimer interface [polypeptide binding]; other site
634456000356	choline dehydrogenase; Validated; Region: PRK02106
634456000357	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
634456000358	GMC oxidoreductase; Region: GMC_oxred_C; pfam05199
634456000359	Solute carrier families 5 and 6-like; solute binding domain; Region: SLC5-6-like_sbd; cl00456
634456000360	Permease for cytosine/purines, uracil, thiamine, allantoin; Region: Transp_cyt_pur; pfam02133
634456000361	Na binding site [ion binding]; other site
634456000362	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cl10015
634456000363	homotrimer interaction site [polypeptide binding]; other site
634456000364	putative active site [active]
634456000365	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
634456000366	Escherichia coli NADP+-dependent gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase PuuC-like; Region: ALDH_GABALDH-PuuC; cd07112
634456000367	NAD(P) binding site [chemical binding]; other site
634456000368	catalytic residues [active]
634456000369	flavin-dependent oxidoreductase, MSMEG_0569 family; Region: MSMEG_0569_nitr; TIGR04046
634456000370	FAD-NAD(P)-binding; Region: NAD_binding_9; pfam13454
634456000371	Family of unknown function (DUF1028); Region: DUF1028; pfam06267
634456000372	Transposase; Region: HTH_Tnp_1; pfam01527
634456000373	HTH-like domain; Region: HTH_21; pfam13276
634456000374	Integrase core domain; Region: rve; pfam00665
634456000375	Integrase core domain; Region: rve_3; pfam13683
634456000376	ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components [Inorganic ion transport and metabolism]; Region: TauA; COG0715
634456000377	NMT1-like family; Region: NMT1_2; pfam13379
634456000378	Response regulator with putative antiterminator output domain [Signal transduction mechanisms]; Region: AmiR; COG3707
634456000379	cheY-homologous receiver domain; Region: REC; smart00448
634456000380	ANTAR domain; Region: ANTAR; pfam03861
634456000381	Nitrate reductases, NapA (Nitrate-R-NapA), NasA, and NarB catalyze the reduction of nitrate to nitrite. Monomeric Nas is located in the cytoplasm and participates in nitrogen assimilation. Dimeric Nap is located in the periplasm and is coupled to quinol...; Region: MopB_Nitrate-R-NapA-like; cd02754
634456000382	molybdopterin cofactor binding site; other site
634456000383	Nitrate reductases, NapA (Nitrate-R-NapA), NasA, and NarB catalyze the reduction of nitrate to nitrite. Monomeric Nas is located in the cytoplasm and participates in nitrogen assimilation. Dimeric Nap is located in the periplasm and is coupled to quinol...; Region: MopB_CT_Nitrate-R-NapA-like; cd02791
634456000384	molybdopterin cofactor binding site; other site
634456000385	Sulfite reductase, alpha subunit (flavoprotein) [Inorganic ion transport and metabolism]; Region: CysJ; COG0369
634456000386	Flavodoxin; Region: Flavodoxin_1; pfam00258
634456000387	Ferredoxin reductase (FNR), an FAD and NAD(P) binding protein, was intially identified as a chloroplast reductase activity, catalyzing the electron transfer from reduced iron-sulfur protein ferredoxin to NADP+ as the final step in the electron transport...; Region: FNR_like; cl06868
634456000388	FAD binding pocket [chemical binding]; other site
634456000389	conserved FAD binding motif [chemical binding]; other site
634456000390	phosphate binding motif [ion binding]; other site
634456000391	beta-alpha-beta structure motif; other site
634456000392	NAD binding pocket [chemical binding]; other site
634456000393	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
634456000394	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
634456000395	Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; pfam13340
634456000396	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
634456000397	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
634456000398	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
634456000399	Nitrite and sulphite reductase 4Fe-4S domain; Region: NIR_SIR; pfam01077
634456000400	Assimilatory nitrite reductase (NirD) family, Rieske domain; Assimilatory nitrate and nitrite reductases convert nitrate through nitrite to ammonium. Members include bacterial and fungal proteins. The bacterial NirD contains a single Rieske domain while...; Region: Rieske_NirD; cd03529
634456000401	NAD(P)H-nitrite reductase [Energy production and conversion]; Region: NirB; COG1251
634456000402	Domain of unknown function (DUF4104); Region: DUF4104; pfam13372
634456000403	Nitrate/nitrite transporter [Inorganic ion transport and metabolism]; Region: NarK; COG2223
634456000404	Nitrate/nitrite transporter [Inorganic ion transport and metabolism]; Region: NarK; COG2223
634456000405	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
634456000406	Nodulin-21 and CCC1-related protein family; Region: Nodulin-21_like_1; cd02432
634456000407	sensor protein QseC; Provisional; Region: PRK10337
634456000408	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
634456000409	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
634456000410	dimer interface [polypeptide binding]; other site
634456000411	phosphorylation site [posttranslational modification]
634456000412	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
634456000413	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
634456000414	active site
634456000415	phosphorylation site [posttranslational modification]
634456000416	intermolecular recognition site; other site
634456000417	dimerization interface [polypeptide binding]; other site
634456000418	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
634456000419	DNA binding site [nucleotide binding]
634456000420	Putative silver efflux pump [Inorganic ion transport and metabolism]; Region: COG3696
634456000421	HlyD family secretion protein; Region: HlyD_2; pfam12700
634456000422	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
634456000423	HlyD family secretion protein; Region: HlyD_3; pfam13437
634456000424	Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: TolC; COG1538
634456000425	Outer membrane efflux protein; Region: OEP; pfam02321
634456000426	Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or C-terminal to the catalytic domain. These enzymes perform site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining...; Region: Ser_Recombinase; cl02788
634456000427	FOG: Transposase [DNA replication, recombination, and repair]; Region: COG5659
634456000428	Domain of unknown function (DUF1852); Region: DUF1852; pfam08908
634456000429	methionine synthase; Provisional; Region: PRK01207
634456000430	CIMS - Cobalamine-independent methonine synthase, or MetE, C-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_C_terminal_like; cd03311
634456000431	substrate binding site [chemical binding]; other site
634456000432	THF binding site; other site
634456000433	zinc-binding site [ion binding]; other site
634456000434	Transcriptional regulator [Transcription]; Region: LysR; COG0583
634456000435	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
634456000436	The C-terminal substrate binding domain of LysR-type transcriptional regulator metR, which regulates the expression of methionine biosynthetic genes, contains type 2 periplasmic binding fold; Region: PBP2_MetR; cd08441
634456000437	putative dimerization interface [polypeptide binding]; other site
634456000438	Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; pfam13340
634456000439	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
634456000440	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
634456000441	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
634456000442	non-specific DNA binding site [nucleotide binding]; other site
634456000443	salt bridge; other site
634456000444	sequence-specific DNA binding site [nucleotide binding]; other site
634456000445	Protein of unknown function (DUF1044); Region: DUF1044; cl01955
634456000446	Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones]; Region: TrxB; COG0492
634456000447	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox_3; pfam13738
634456000448	arsenical resistance protein ArsH; Region: resist_ArsH; TIGR02690
634456000449	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
634456000450	arsenical pump membrane protein; Provisional; Region: PRK15445
634456000451	Anion permease ArsB.  These permeases have been shown to export arsenate and antimonite in eubacteria and archaea.  A typical ArsB permease contains 8-13 transmembrane helices and can function either independently as a chemiosmotic transporter or as a...; Region: ArsB_permease; cd01118
634456000452	transmembrane helices; other site
634456000453	Arsenate Reductase (ArsC) family, ArsC subfamily; arsenic reductases similar to that encoded by arsC on the R733 plasmid of Escherichia coli. E. coli ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], the first step in the...; Region: ArsC_ArsC; cd03034
634456000454	ArsC family; Region: ArsC; pfam03960
634456000455	catalytic residues [active]
634456000456	Protein of unknown function DUF45; Region: DUF45; pfam01863
634456000457	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases [Defense mechanisms]; Region: COG0610
634456000458	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; pfam04313
634456000459	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
634456000460	ATP binding site [chemical binding]; other site
634456000461	putative Mg++ binding site [ion binding]; other site
634456000462	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
634456000463	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
634456000464	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
634456000465	Type I restriction-modification system methyltransferase subunit [Defense mechanisms]; Region: HsdM; COG0286
634456000466	HsdM N-terminal domain; Region: HsdM_N; pfam12161
634456000467	Methyltransferase domain; Region: Methyltransf_26; pfam13659
634456000468	Eco57I restriction-modification methylase; Region: Eco57I; pfam07669
634456000469	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
634456000470	HTH-like domain; Region: HTH_21; pfam13276
634456000471	Integrase core domain; Region: rve; pfam00665
634456000472	Integrase core domain; Region: rve_3; pfam13683
634456000473	Transposase; Region: HTH_Tnp_1; pfam01527
634456000474	CCC1-related family of proteins; Region: CCC1_like; cl00278
634456000475	Arsenate Reductase (ArsC) family, ArsC subfamily; arsenic reductases similar to that encoded by arsC on the R733 plasmid of Escherichia coli. E. coli ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], the first step in the...; Region: ArsC_ArsC; cd03034
634456000476	ArsC family; Region: ArsC; pfam03960
634456000477	catalytic residues [active]
634456000478	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cl17221
634456000479	Transposase; Region: HTH_Tnp_1; cl17663
634456000480	putative transposase OrfB; Reviewed; Region: PHA02517
634456000481	HTH-like domain; Region: HTH_21; pfam13276
634456000482	Integrase core domain; Region: rve; pfam00665
634456000483	Integrase core domain; Region: rve_3; pfam13683
634456000484	Integrase core domain; Region: rve; pfam00665
634456000485	Integrase core domain; Region: rve_3; pfam13683
634456000486	Transcriptional regulator [Transcription]; Region: LysR; COG0583
634456000487	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
634456000488	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator similar to DntR, which is involved in the catabolism of dinitrotoluene; contains the type 2 periplasmic binding fold; Region: PBP2_DntR_like_1; cd08460
634456000489	putative substrate binding pocket [chemical binding]; other site
634456000490	putative dimerization interface [polypeptide binding]; other site
634456000491	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
634456000492	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
634456000493	Transposase; Region: HTH_Tnp_1; cl17663
634456000494	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
634456000495	HTH-like domain; Region: HTH_21; pfam13276
634456000496	Integrase core domain; Region: rve; pfam00665
634456000497	Integrase core domain; Region: rve_3; pfam13683
634456000498	PIN domain of ribonucleases (toxins), VapC and FitB, of prokaryotic toxin/antitoxin operons, Pyrococcus horikoshii protein PH0500, and other similar bacterial and archaeal homologs; Region: PIN_VapC-FitB; cd09881
634456000499	oligomeric interface; other site
634456000500	putative active site [active]
634456000501	homodimer interface [polypeptide binding]; other site
634456000502	Integrase core domain; Region: rve; pfam00665
634456000503	Winged helix-turn helix; Region: HTH_29; pfam13551
634456000504	Integrase core domain; Region: rve; pfam00665
634456000505	Transposase; Region: HTH_Tnp_1; pfam01527
634456000506	HTH-like domain; Region: HTH_21; pfam13276
634456000507	Integrase core domain; Region: rve; pfam00665
634456000508	Integrase core domain; Region: rve_3; pfam13683
634456000509	K+ potassium transporter; Region: K_trans; pfam02705
634456000510	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: Tra5; COG2801
634456000511	HTH-like domain; Region: HTH_21; pfam13276
634456000512	Integrase core domain; Region: rve; pfam00665
634456000513	Integrase core domain; Region: rve_3; pfam13683
634456000514	Transposase; Region: HTH_Tnp_1; pfam01527
634456000515	K+ potassium transporter; Region: K_trans; cl15781
634456000516	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
634456000517	Walker A motif; other site
634456000518	ATP binding site [chemical binding]; other site
634456000519	Walker B motif; other site
634456000520	arginine finger; other site
634456000521	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG4584
634456000522	Integrase core domain; Region: rve; pfam00665
634456000523	Transposase DDE domain group 1; Region: DDE_Tnp_1_4; pfam13701
634456000524	TrwC relaxase; Region: TrwC; pfam08751
634456000525	Integrase core domain; Region: rve; pfam00665
634456000526	Integrase core domain; Region: rve_3; pfam13683
634456000527	Transposase DDE domain group 1; Region: DDE_Tnp_1_4; pfam13701
634456000528	conjugative coupling factor TraD, SXT/TOL subfamily; Region: SXT_TraD; TIGR03743
634456000529	TraM recognition site of TraD and TraG; Region: TraG-D_C; cl17375
634456000530	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
634456000531	N-acetyl-D-glucosamine binding site [chemical binding]; other site
634456000532	catalytic residue [active]
634456000533	Dot/Icm secretion system ATPase DotB; Region: dot_icm_DotB; TIGR02524
634456000534	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
634456000535	Walker A motif; other site
634456000536	ATP binding site [chemical binding]; other site
634456000537	Walker B motif; other site
634456000538	RelB antitoxin; Region: RelB; cl01171
634456000539	Cytotoxic translational repressor of toxin-antitoxin stability system [Translation, ribosomal structure and biogenesis / Cell division and chromosome partitioning]; Region: RelE; COG2026
634456000540	AAA-like domain; Region: AAA_10; pfam12846
634456000541	Transposase; Region: HTH_Tnp_1; pfam01527
634456000542	HTH-like domain; Region: HTH_21; pfam13276
634456000543	Integrase core domain; Region: rve; pfam00665
634456000544	Integrase core domain; Region: rve_3; pfam13683
634456000545	Protein of unknown function (DUF2859); Region: DUF2859; cl12633
634456000546	Transposase DDE domain group 1; Region: DDE_Tnp_1_4; pfam13701
634456000547	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
634456000548	active site
634456000549	Transposase; Region: HTH_Tnp_1; cl17663
634456000550	HTH-like domain; Region: HTH_21; pfam13276
634456000551	Integrase core domain; Region: rve; pfam00665
634456000552	Integrase core domain; Region: rve_3; pfam13683
634456000553	Hint domain; Region: Hint_2; pfam13403
634456000554	FOG: Transposase [DNA replication, recombination, and repair]; Region: COG5659
634456000555	Transposase DDE domain group 1; Region: DDE_Tnp_1_4; pfam13701
634456000556	PIN (PilT N terminus) domain: Superfamily; Region: PIN_SF; cl14812
634456000557	putative active site [active]
634456000558	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: Tra5; COG2801
634456000559	HTH-like domain; Region: HTH_21; pfam13276
634456000560	Integrase core domain; Region: rve; pfam00665
634456000561	Integrase core domain; Region: rve_3; pfam13683
634456000562	Transposase; Region: HTH_Tnp_1; pfam01527
634456000563	PIN (PilT N terminus) domain: Superfamily; Region: PIN_SF; cl14812
634456000564	Antitoxin of toxin-antitoxin stability system [Cell division and chromosome partitioning]; Region: Phd; COG4118
634456000565	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
634456000566	active site
634456000567	DNA binding site [nucleotide binding]
634456000568	Int/Topo IB signature motif; other site
634456000569	Putative silver efflux pump [Inorganic ion transport and metabolism]; Region: COG3696
634456000570	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
634456000571	Outer membrane efflux protein; Region: OEP; pfam02321
634456000572	Outer membrane efflux protein; Region: OEP; pfam02321
634456000573	Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism]; Region: CzcD; COG1230
634456000574	Helix-Turn-Helix DNA binding domain of the CadR- and PbrR-like transcription regulators; Region: HTH_CadR-PbrR-like; cd04785
634456000575	DNA binding residues [nucleotide binding]
634456000576	Cu(I)-responsive transcriptional regulator; Region: CueR; TIGR02044
634456000577	dimer interface [polypeptide binding]; other site
634456000578	putative metal binding site [ion binding]; other site
634456000579	Outer membrane protein family (DUF1597); Region: DUF1597; pfam07642
634456000580	potassium-transporting ATPase subunit A; Provisional; Region: PRK05482
634456000581	potassium-transporting ATPase subunit B; Provisional; Region: PRK01122
634456000582	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
634456000583	haloacid dehalogenase-like hydrolase; Region: HAD; pfam12710
634456000584	Soluble P-type ATPase [General function prediction only]; Region: COG4087
634456000585	potassium-transporting ATPase subunit C; Provisional; Region: PRK13999
634456000586	Osmosensitive K+ channel histidine kinase [Signal transduction mechanisms]; Region: KdpD; COG2205
634456000587	Osmosensitive K+ channel His kinase sensor domain; Region: KdpD; pfam02702
634456000588	USP domain is located between the N-terminal sensor domain and C-terminal catalytic domain of this Osmosensitive K+ channel histidine kinase family. The family of KdpD sensor kinase proteins regulates the kdpFABC operon responsible for potassium...; Region: USP_OKCHK; cd01987
634456000589	Ligand Binding Site [chemical binding]; other site
634456000590	Domain of unknown function (DUF4118); Region: DUF4118; pfam13493
634456000591	GAF domain; Region: GAF_3; pfam13492
634456000592	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
634456000593	dimer interface [polypeptide binding]; other site
634456000594	phosphorylation site [posttranslational modification]
634456000595	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
634456000596	ATP binding site [chemical binding]; other site
634456000597	Mg2+ binding site [ion binding]; other site
634456000598	G-X-G motif; other site
634456000599	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
634456000600	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
634456000601	active site
634456000602	phosphorylation site [posttranslational modification]
634456000603	intermolecular recognition site; other site
634456000604	dimerization interface [polypeptide binding]; other site
634456000605	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
634456000606	DNA binding site [nucleotide binding]
634456000607	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
634456000608	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
634456000609	short chain dehydrogenase; Provisional; Region: PRK06180
634456000610	17beta hydroxysteroid dehydrogenase-like, classical (c) SDRs; Region: 17beta-HSD-like_SDR_c; cd05374
634456000611	NADP binding site [chemical binding]; other site
634456000612	active site
634456000613	steroid binding site; other site
634456000614	Type 1 glutamine amidotransferase (GATase1)-like domain found in proteins similar to Escherichia coli Hsp31 protein; Region: GATase1_Hsp31_like; cd03141
634456000615	Putative intracellular protease/amidase [General function prediction only]; Region: ThiJ; COG0693
634456000616	potential catalytic triad [active]
634456000617	conserved cys residue [active]
634456000618	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases [Defense mechanisms]; Region: COG0610
634456000619	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; pfam04313
634456000620	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
634456000621	ATP binding site [chemical binding]; other site
634456000622	putative Mg++ binding site [ion binding]; other site
634456000623	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
634456000624	Type I restriction-modification system methyltransferase subunit [Defense mechanisms]; Region: HsdM; COG0286
634456000625	HsdM N-terminal domain; Region: HsdM_N; pfam12161
634456000626	Methyltransferase domain; Region: Methyltransf_26; pfam13659
634456000627	Helix-turn-helix domain; Region: HTH_17; pfam12728
634456000628	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
634456000629	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
634456000630	active site
634456000631	DNA binding site [nucleotide binding]
634456000632	Int/Topo IB signature motif; other site
634456000633	Virulence-associated protein and related proteins [Function unknown]; Region: VagC; COG4456
634456000634	PIN domain of ribonucleases (toxins), VapC and FitB, of prokaryotic toxin/antitoxin operons, Pyrococcus horikoshii protein PH0500, and other similar bacterial and archaeal homologs; Region: PIN_VapC-FitB; cd09881
634456000635	oligomeric interface; other site
634456000636	putative active site [active]
634456000637	homodimer interface [polypeptide binding]; other site
634456000638	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG4584
634456000639	Integrase core domain; Region: rve; pfam00665
634456000640	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
634456000641	Walker A motif; other site
634456000642	ATP binding site [chemical binding]; other site
634456000643	Walker B motif; other site
634456000644	arginine finger; other site
634456000645	Post-segregation antitoxin CcdA; Region: CcdA; pfam07362
634456000646	CcdB protein; Region: CcdB; cl03380
634456000647	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
634456000648	Transposase DDE domain group 1; Region: DDE_Tnp_1_4; pfam13701
634456000649	FOG: Transposase [DNA replication, recombination, and repair]; Region: COG5659
634456000650	Major Facilitator Superfamily; Region: MFS_1; pfam07690
634456000651	melibiose:sodium symporter; Provisional; Region: PRK10429; cl15392
634456000652	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
634456000653	Transposase; Region: HTH_Tnp_1; cl17663
634456000654	Helix-turn-helix domain; Region: HTH_28; pfam13518
634456000655	Winged helix-turn helix; Region: HTH_29; pfam13551
634456000656	Homeodomain-like domain; Region: HTH_32; pfam13565
634456000657	Integrase core domain; Region: rve; pfam00665
634456000658	Integrase core domain; Region: rve_3; pfam13683
634456000659	Stage 0 sporulation protein J (antagonist of Soj) containing ParB-like nuclease domain [Transcription]; Region: Spo0J; COG1475
634456000660	ParB-like nuclease domain; Region: ParBc; pfam02195
634456000661	Adenine-specific DNA methylase [DNA replication, recombination, and repair]; Region: COG0827
634456000662	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
634456000663	S-adenosylmethionine binding site [chemical binding]; other site
634456000664	DNA methylase [Transcription / DNA replication, recombination, and repair]; Region: COG4646
634456000665	DEAD-like helicases superfamily; Region: DEXDc; smart00487
634456000666	DNA methylase [Transcription / DNA replication, recombination, and repair]; Region: COG4646
634456000667	helicase superfamily c-terminal domain; Region: HELICc; smart00490
634456000668	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
634456000669	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
634456000670	Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; pfam13340
634456000671	Plasmid encoded RepA protein; Region: RepA_C; pfam04796
634456000672	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
634456000673	active site
634456000674	DNA binding site [nucleotide binding]
634456000675	Int/Topo IB signature motif; other site
634456000676	FOG: Transposase [DNA replication, recombination, and repair]; Region: COG5659
634456000677	Phosphate-starvation-inducible E; Region: PsiE; pfam06146
634456000678	DDE superfamily endonuclease; Region: DDE_5; cl17874
634456000679	putative transposase OrfB; Reviewed; Region: PHA02517
634456000680	HTH-like domain; Region: HTH_21; pfam13276
634456000681	Integrase core domain; Region: rve; pfam00665
634456000682	Integrase core domain; Region: rve_3; pfam13683
634456000683	Conjugal transfer protein TraD; Region: TraD; pfam06412
634456000684	MobA/MobL family; Region: MobA_MobL; pfam03389
634456000685	Helix-turn-helix domain; Region: HTH_36; pfam13730
634456000686	Endodeoxyribonuclease RusA; Region: RusA; pfam05866
634456000687	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
634456000688	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
634456000689	active site
634456000690	Int/Topo IB signature motif; other site
634456000691	hypothetical protein; Validated; Region: PRK00124
634456000692	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
634456000693	dimer interface [polypeptide binding]; other site
634456000694	bicyclomycin/multidrug efflux system; Provisional; Region: PRK11102
634456000695	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
634456000696	putative substrate translocation pore; other site
634456000697	Uncharacterized conserved protein [Function unknown]; Region: COG2835
634456000698	Uncharacterized protein, similar to the N-terminal domain of Lon protease [General function prediction only]; Region: COG2802
634456000699	Thioredoxin domain-containing protein [Posttranslational modification, protein turnover, chaperones]; Region: COG3118
634456000700	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
634456000701	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
634456000702	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
634456000703	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
634456000704	ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271
634456000705	Creatinine amidohydrolase; Region: Creatininase; pfam02633
634456000706	Uncharacterized conserved protein [Function unknown]; Region: COG3391
634456000707	40-residue YVTN family beta-propeller repeat; Region: beta_rpt_yvtn; TIGR02276
634456000708	AAA ATPase domain; Region: AAA_16; pfam13191
634456000709	Uncharacterized conserved protein (DUF2075); Region: DUF2075; pfam09848
634456000710	Uncharacterized conserved protein [Function unknown]; Region: COG3410
634456000711	Scaffold protein Nfu/NifU N terminal; Region: Nfu_N; pfam08712
634456000712	Thioredoxin-like proteins and domains [Posttranslational modification, protein turnover, chaperones]; Region: COG0694
634456000713	Nitroreductase-like family 5.  A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and...; Region: Nitroreductase_5; cd02148
634456000714	putative FMN binding site [chemical binding]; other site
634456000715	tRNA threonylcarbamoyl adenosine modification protein YeaZ; Region: T6A_YeaZ; TIGR03725
634456000716	Glycoprotease family; Region: Peptidase_M22; pfam00814
634456000717	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
634456000718	Coenzyme A binding pocket [chemical binding]; other site
634456000719	phosphoribosylamine--glycine ligase; Provisional; Region: PRK00885
634456000720	Phosphoribosylglycinamide synthetase, N domain; Region: GARS_N; pfam02844
634456000721	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Region: GARS_A; pfam01071
634456000722	Phosphoribosylglycinamide synthetase, C domain; Region: GARS_C; pfam02843
634456000723	exodeoxyribonuclease VII large subunit; Reviewed; Region: xseA; PRK00286
634456000724	ExoVII_LU_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold domain of Escherichia coli exodeoxyribonuclease VII (ExoVII) large subunit. E. coli ExoVII is composed of two non-identical subunits. E. coli ExoVII is a...; Region: ExoVII_LU_OBF; cd04489
634456000725	generic binding surface II; other site
634456000726	generic binding surface I; other site
634456000727	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cd01494
634456000728	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
634456000729	catalytic residue [active]
634456000730	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
634456000731	Mycobacterium tuberculosis succinate-semialdehyde dehydrogenase 1-like; Region: ALDH_SSADH1_GabD1; cd07100
634456000732	NAD(P) binding site [chemical binding]; other site
634456000733	catalytic residues [active]
634456000734	Zn-dependent alcohol dehydrogenases [General function prediction only]; Region: AdhP; COG1064
634456000735	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD3; cd08297
634456000736	NAD binding site [chemical binding]; other site
634456000737	substrate binding site [chemical binding]; other site
634456000738	catalytic Zn binding site [ion binding]; other site
634456000739	tetramer interface [polypeptide binding]; other site
634456000740	structural Zn binding site [ion binding]; other site
634456000741	NAD/NADP transhydrogenase beta subunit [Energy production and conversion]; Region: PntB; COG1282
634456000742	NAD(P) transhydrogenase beta subunit; Region: PNTB; pfam02233
634456000743	Domain of unknown function (DUF3814); Region: DUF3814; pfam12769
634456000744	Rubrum transdehydrogenase NAD-binding and catalytic domains; Region: Rubrum_tdh; cd05304
634456000745	NAD/NADP transhydrogenase alpha subunit [Energy production and conversion]; Region: PntA; COG3288
634456000746	ligand binding site [chemical binding]; other site
634456000747	homodimer interface [polypeptide binding]; other site
634456000748	NAD(P) binding site [chemical binding]; other site
634456000749	trimer interface B [polypeptide binding]; other site
634456000750	trimer interface A [polypeptide binding]; other site
634456000751	aspartate-semialdehyde dehydrogenase; Provisional; Region: PRK14874
634456000752	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
634456000753	Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase C (SdhC) subunit; composed of bacterial SdhC and eukaryotic large cytochrome b binding (CybL) proteins. SQR catalyzes the oxidation of succinate to fumarate coupled to the...; Region: SQR_TypeC_SdhC; cd03499
634456000754	Iron-sulfur protein interface; other site
634456000755	proximal quinone binding site [chemical binding]; other site
634456000756	SdhD (CybS) interface [polypeptide binding]; other site
634456000757	proximal heme binding site [chemical binding]; other site
634456000758	Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase D (SdhD) subunit-like; composed of predominantly uncharacterized bacterial proteins with similarity to the E. coli SdhD subunit. One characterized protein is the respiratory...; Region: SQR_TypeC_SdhD_like; cd03495
634456000759	putative SdhC subunit interface [polypeptide binding]; other site
634456000760	putative proximal heme binding site [chemical binding]; other site
634456000761	putative Iron-sulfur protein interface [polypeptide binding]; other site
634456000762	putative proximal quinone binding site; other site
634456000763	succinate dehydrogenase flavoprotein subunit; Reviewed; Region: sdhA; PRK09078
634456000764	L-aspartate oxidase; Provisional; Region: PRK06175
634456000765	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
634456000766	succinate dehydrogenase iron-sulfur subunit; Reviewed; Region: sdhB; PRK05950
634456000767	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
634456000768	Putative phosphatase (DUF442); Region: DUF442; cl17385
634456000769	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
634456000770	EamA-like transporter family; Region: EamA; pfam00892
634456000771	Phosphoglycerate kinase; Region: PGK; pfam00162
634456000772	Phosphoglycerate kinase (PGK) is a monomeric enzyme which catalyzes the transfer of the high-energy phosphate group of 1,3-bisphosphoglycerate to ADP, forming ATP and 3-phosphoglycerate. This reaction represents the first of the two substrate-level...; Region: Phosphoglycerate_kinase; cd00318
634456000773	substrate binding site [chemical binding]; other site
634456000774	hinge regions; other site
634456000775	ADP binding site [chemical binding]; other site
634456000776	catalytic site [active]
634456000777	Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase [Carbohydrate transport and metabolism]; Region: GapA; COG0057
634456000778	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
634456000779	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
634456000780	Transketolase [Carbohydrate transport and metabolism]; Region: TktA; COG0021
634456000781	Thiamine pyrophosphate (TPP) enzyme family, TPP-binding module; found in many key metabolic enzymes which use TPP (also known as thiamine diphosphate) as a cofactor. These enzymes include, among others, the E1 components of the pyruvate, the acetoin and...; Region: TPP_enzymes; cl01629
634456000782	TPP-binding site [chemical binding]; other site
634456000783	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
634456000784	PYR/PP interface [polypeptide binding]; other site
634456000785	dimer interface [polypeptide binding]; other site
634456000786	TPP binding site [chemical binding]; other site
634456000787	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
634456000788	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
634456000789	KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS); Region: KBL_like; cd06454
634456000790	substrate-cofactor binding pocket; other site
634456000791	pyridoxal 5'-phosphate binding site [chemical binding]; other site
634456000792	catalytic residue [active]
634456000793	DsbA family, Com1-like subfamily; composed of proteins similar to Com1, a 27-kDa outer membrane-associated immunoreactive protein originally found in both acute and chronic disease strains of the pathogenic bacteria Coxiella burnetti. It contains a CXXC...; Region: DsbA_Com1_like; cd03023
634456000794	DSBA-like thioredoxin domain; Region: DSBA; pfam01323
634456000795	catalytic residues [active]
634456000796	Gamma-glutamyltransferase [Amino acid transport and metabolism]; Region: Ggt; cl08040
634456000797	recombinase A; Provisional; Region: recA; PRK09354
634456000798	RecA is a  bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response.  RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983
634456000799	hexamer interface [polypeptide binding]; other site
634456000800	Walker A motif; other site
634456000801	ATP binding site [chemical binding]; other site
634456000802	Walker B motif; other site
634456000803	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
634456000804	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
634456000805	Coenzyme A binding pocket [chemical binding]; other site
634456000806	N-terminal domain of molybdenum-binding protein [General function prediction only]; Region: ModE; COG2005
634456000807	glucan biosynthesis protein G; Provisional; Region: mdoG; PRK13274
634456000808	glucan biosynthesis protein D; Provisional; Region: mdoD; PRK13273
634456000809	Glucan_BSP_ModH catalyzes the elongation of beta-1,2 polyglucose chains of glucan; Region: Glucan_BSP_ModH; cd04191
634456000810	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
634456000811	Ligand binding site; other site
634456000812	DXD motif; other site
634456000813	N-acetylglucosamine-6-phosphate deacetylase; Region: nagA; TIGR00221
634456000814	N-acetylglucosamine-6-phosphate deacetylase, NagA, catalyzes the hydrolysis of the N-acetyl group of N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to glucosamine 6-phosphate and acetate. This is the first committed step in the biosynthetic pathway to...; Region: NagA; cd00854
634456000815	active site
634456000816	dimer interface [polypeptide binding]; other site
634456000817	Fucose permease [Carbohydrate transport and metabolism]; Region: FucP; COG0738
634456000818	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
634456000819	putative substrate translocation pore; other site
634456000820	DNA polymerase III subunits gamma and tau; Validated; Region: PRK09111
634456000821	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
634456000822	Walker A motif; other site
634456000823	ATP binding site [chemical binding]; other site
634456000824	Walker B motif; other site
634456000825	arginine finger; other site
634456000826	DNA polymerase III subunits gamma and tau domain III; Region: DNA_pol3_gamma3; pfam12169
634456000827	DNA polymerase III gamma and tau subunits C terminal; Region: DUF3646; pfam12362
634456000828	hypothetical protein; Validated; Region: PRK00153
634456000829	recombination protein RecR; Reviewed; Region: recR; PRK00076
634456000830	RecR protein; Region: RecR; pfam02132
634456000831	TOPRIM_recR: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in Escherichia coli RecR.  RecR participates in the RecFOR pathway of homologous recombinational repair in prokaryotes. This pathway provides a...; Region: TOPRIM_recR; cd01025
634456000832	putative active site [active]
634456000833	putative metal-binding site [ion binding]; other site
634456000834	tetramer interface [polypeptide binding]; other site
634456000835	short chain dehydrogenase; Provisional; Region: PRK09134
634456000836	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
634456000837	NAD(P) binding site [chemical binding]; other site
634456000838	active site
634456000839	Dihydroneopterin aldolase; Region: FolB; pfam02152
634456000840	active site
634456000841	TIGR02300 family protein; Region: FYDLN_acid
634456000842	Protein of unknown function (FYDLN_acid); Region: FYDLN_acid; pfam09538
634456000843	3-phosphoshikimate 1-carboxyvinyltransferase; Provisional; Region: PRK02427
634456000844	EPSP synthase domain. 3-phosphoshikimate 1-carboxyvinyltransferase (5-enolpyruvylshikimate-3-phosphate synthase) (EC 2.5.1.19) catalyses the reaction between shikimate-3-phosphate (S3P) and phosphoenolpyruvate (PEP) to form...; Region: EPSP_synthase; cd01556
634456000845	hinge; other site
634456000846	active site
634456000847	cytidylate kinase; Provisional; Region: cmk; PRK00023
634456000848	Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor; Region: CMPK; cd02020
634456000849	CMP-binding site; other site
634456000850	The sites determining sugar specificity; other site
634456000851	30S ribosomal protein S1; Reviewed; Region: rpsA; PRK06299
634456000852	S1_RPS1_repeat_ec1_hs1: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec1_hs1; cd05687
634456000853	RNA binding site [nucleotide binding]; other site
634456000854	S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465
634456000855	RNA binding site [nucleotide binding]; other site
634456000856	S1_RPS1_repeat_ec3: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec3; cd05688
634456000857	RNA binding site [nucleotide binding]; other site
634456000858	S1_RPS1_repeat_ec4: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec4; cd05689
634456000859	RNA binding site [nucleotide binding]; other site
634456000860	S1_RPS1_repeat_ec5: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec5; cd05690
634456000861	RNA binding site [nucleotide binding]; other site
634456000862	S1_RPS1_repeat_ec6: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec6; cd05691
634456000863	RNA binding site [nucleotide binding]; other site
634456000864	Major royal jelly protein; Region: MRJP; pfam03022
634456000865	NTPase/HAM1.  This family consists of the HAM1 protein and pyrophosphate-releasing xanthosine/ inosine triphosphatase. HAM1 protects the cell against mutagenesis by the base analog 6-N-hydroxylaminopurine (HAP) in E. Coli and S. cerevisiae. A...; Region: HAM1; cd00515
634456000866	active site
634456000867	dimerization interface [polypeptide binding]; other site
634456000868	ribonuclease PH; Reviewed; Region: rph; PRK00173
634456000869	Ribonuclease PH; Region: RNase_PH_bact; cd11362
634456000870	hexamer interface [polypeptide binding]; other site
634456000871	active site
634456000872	heat-inducible transcription repressor; Provisional; Region: hrcA; PRK00082
634456000873	Winged helix-turn-helix transcription repressor, HrcA DNA-binding; Region: HrcA_DNA-bdg; pfam03444
634456000874	Membrane carboxypeptidase/penicillin-binding protein [Cell envelope biogenesis, outer membrane]; Region: MrcA; COG5009
634456000875	Transglycosylase; Region: Transgly; pfam00912
634456000876	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
634456000877	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
634456000878	This domain is found in peptide chain release factors; Region: PCRF; smart00937
634456000879	Protein chain release factor B [Translation, ribosomal structure and biogenesis]; Region: PrfB; COG1186
634456000880	RF-1 domain; Region: RF-1; pfam00472
634456000881	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
634456000882	Biopolymer transport proteins [Intracellular trafficking and secretion]; Region: TolQ; COG0811
634456000883	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
634456000884	Biopolymer transport protein ExbD/TolR; Region: ExbD; pfam02472
634456000885	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
634456000886	Biopolymer transport protein ExbD/TolR; Region: ExbD; pfam02472
634456000887	rod shape-determining protein RodA; Region: rodA_shape; TIGR02210
634456000888	penicillin-binding protein 2; Region: pbp2_mrdA; TIGR03423
634456000889	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
634456000890	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
634456000891	rod shape-determining protein MreC; Provisional; Region: PRK13922
634456000892	rod shape-determining protein MreC; Region: MreC; pfam04085
634456000893	rod shape-determining protein MreB; Provisional; Region: PRK13927
634456000894	MreB and similar proteins; Region: MreB_like; cd10225
634456000895	nucleotide binding site [chemical binding]; other site
634456000896	Mg binding site [ion binding]; other site
634456000897	putative protofilament interaction site [polypeptide binding]; other site
634456000898	RodZ interaction site [polypeptide binding]; other site
634456000899	2-isopropylmalate synthase; Validated; Region: PRK00915
634456000900	2-isopropylmalate synthase (IPMS), N-terminal catalytic TIM barrel domain; Region: DRE_TIM_IPMS; cd07940
634456000901	active site
634456000902	catalytic residues [active]
634456000903	metal binding site [ion binding]; metal-binding site
634456000904	LeuA allosteric (dimerisation) domain; Region: LeuA_dimer; smart00917
634456000905	Cytochrome oxidase assembly protein; Region: COX15-CtaA; cl15852
634456000906	Uncharacterized protein required for cytochrome oxidase assembly [Posttranslational modification, protein turnover, chaperones]; Region: CtaA; COG1612
634456000907	Uncharacterized conserved protein [Function unknown]; Region: COG0398
634456000908	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
634456000909	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
634456000910	bicyclomycin/multidrug efflux system; Provisional; Region: PRK11102
634456000911	putative substrate translocation pore; other site
634456000912	PAS fold; Region: PAS_7; pfam12860
634456000913	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
634456000914	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
634456000915	dimer interface [polypeptide binding]; other site
634456000916	phosphorylation site [posttranslational modification]
634456000917	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
634456000918	ATP binding site [chemical binding]; other site
634456000919	Mg2+ binding site [ion binding]; other site
634456000920	G-X-G motif; other site
634456000921	Response regulator receiver domain; Region: Response_reg; pfam00072
634456000922	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
634456000923	active site
634456000924	phosphorylation site [posttranslational modification]
634456000925	intermolecular recognition site; other site
634456000926	dimerization interface [polypeptide binding]; other site
634456000927	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
634456000928	active site
634456000929	Fusaric acid resistance protein family; Region: FUSC; pfam04632
634456000930	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
634456000931	Putative glycerate kinase [Carbohydrate transport and metabolism]; Region: GckA; COG2379
634456000932	Domain of unknown function (DUF4147); Region: DUF4147; pfam13660
634456000933	MOFRL family; Region: MOFRL; pfam05161
634456000934	Uracil-DNA glycosylases (UDG) and related enzymes; Region: UDG_like; cl00483
634456000935	ligand binding site [chemical binding]; other site
634456000936	active site
634456000937	Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010
634456000938	Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010
634456000939	Cytochrome c; Region: Cytochrom_C; pfam00034
634456000940	PQQ-dependent dehydrogenase, methanol/ethanol family; Region: PQQ_enz_alc_DH; TIGR03075
634456000941	PQQ_like domain of the quinohemoprotein alcohol dehydrogenase (type II); Region: PQQ_ADH_II; cd10279
634456000942	Trp docking motif [polypeptide binding]; other site
634456000943	cytochrome domain interface [polypeptide binding]; other site
634456000944	active site
634456000945	Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010
634456000946	Cytochrome c; Region: Cytochrom_C; pfam00034
634456000947	2'-5' RNA ligase; Region: 2_5_ligase; TIGR02258
634456000948	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
634456000949	Bacterial BAX inhibitor (BI)-1/YccA-like proteins; Region: BI-1-like_bacterial; cd10432
634456000950	cytochrome o ubiquinol oxidase subunit II; Provisional; Region: PRK10525
634456000951	Cytochrome C oxidase subunit II, periplasmic domain; Region: COX2; pfam00116
634456000952	COX Aromatic Rich Motif; Region: COX_ARM; pfam06481
634456000953	Heme/copper-type cytochrome/quinol oxidases, subunit 1 [Energy production and conversion]; Region: CyoB; COG0843
634456000954	Ubiquinol oxidase subunit I.  Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane.  It catalyzes the reduction of O2 and simultaneously pumps protons...; Region: Ubiquinol_Oxidase_I; cd01662
634456000955	D-pathway; other site
634456000956	Putative ubiquinol binding site [chemical binding]; other site
634456000957	Low-spin heme (heme b) binding site [chemical binding]; other site
634456000958	Putative water exit pathway; other site
634456000959	Binuclear center (heme o3/CuB) [ion binding]; other site
634456000960	K-pathway; other site
634456000961	Putative proton exit pathway; other site
634456000962	Ubiquinol oxidase subunit III subfamily. Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane.  It catalyzes the reduction of O2 and simultaneously...; Region: Ubiquinol_oxidase_III; cd02863
634456000963	Subunit I/III interface [polypeptide binding]; other site
634456000964	Subunit III/IV interface [polypeptide binding]; other site
634456000965	cytochrome o ubiquinol oxidase subunit IV; Region: CyoD; TIGR02847
634456000966	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
634456000967	4Fe-4S binding domain; Region: Fer4; pfam00037
634456000968	Domain of unknown function (DUF3470); Region: DUF3470; pfam11953
634456000969	Superfamily II DNA and RNA helicases [DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis]; Region: SrmB; COG0513
634456000970	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
634456000971	nucleotide binding region [chemical binding]; other site
634456000972	ATP-binding site [chemical binding]; other site
634456000973	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
634456000974	Leucyl aminopeptidase [Amino acid transport and metabolism]; Region: PepB; COG0260
634456000975	interface (dimer of trimers) [polypeptide binding]; other site
634456000976	Substrate-binding/catalytic site; other site
634456000977	Zn-binding sites [ion binding]; other site
634456000978	MarR family; Region: MarR; pfam01047
634456000979	The members of this subfamily catalyze the formation of a phosphodiester bond between a membrane-associated undecaprenyl-phosphate (Und-P) molecule and N-acetylhexosamine 1-phosphate, which is usually donated by a soluble UDP-N-acetylhexosamine precursor; Region: GT_WbpL_WbcO_like; cd06854
634456000980	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase [Cell envelope biogenesis, outer membrane]; Region: Rfe; COG0472
634456000981	Mg++ binding site [ion binding]; other site
634456000982	putative catalytic motif [active]
634456000983	putative substrate binding site [chemical binding]; other site
634456000984	Predicted nucleoside-diphosphate sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG1086
634456000985	UDP-Glcnac (UDP-linked N-acetylglucosamine) inverting 4,6-dehydratase, extended (e) SDRs; Region: UDP_invert_4-6DH_SDR_e; cd05237
634456000986	NAD(P) binding site [chemical binding]; other site
634456000987	homodimer interface [polypeptide binding]; other site
634456000988	substrate binding site [chemical binding]; other site
634456000989	active site
634456000990	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
634456000991	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
634456000992	inhibitor-cofactor binding pocket; inhibition site
634456000993	pyridoxal 5'-phosphate binding site [chemical binding]; other site
634456000994	catalytic residue [active]
634456000995	dihydroorotase; Validated; Region: PRK09060
634456000996	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
634456000997	Dihydroorotase (DHOase), subgroup IIb; DHOases catalyze the reversible interconversion of carbamoyl aspartate to dihydroorotate, a key reaction in pyrimidine biosynthesis. This group contains the archeal members of the DHOase family; Region: DHOase_IIb; cd01318
634456000998	active site
634456000999	glutathione reductase; Validated; Region: PRK06116
634456001000	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
634456001001	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
634456001002	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
634456001003	Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 [Energy production and conversion]; Region: Hmp; COG1018
634456001004	Ferredoxin-NADP+ (oxido)reductase is an FAD-containing enzyme that catalyzes the reversible electron transfer between NADP(H) and electron carrier proteins such as ferredoxin and flavodoxin. Isoforms of these flavoproteins (i.e. having a non-covalently...; Region: FNR1; cd06195
634456001005	FAD binding pocket [chemical binding]; other site
634456001006	FAD binding motif [chemical binding]; other site
634456001007	phosphate binding motif [ion binding]; other site
634456001008	beta-alpha-beta structure motif; other site
634456001009	NAD binding pocket [chemical binding]; other site
634456001010	DEAD-like helicases superfamily; Region: DEXDc; smart00487
634456001011	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
634456001012	ATP binding site [chemical binding]; other site
634456001013	putative Mg++ binding site [ion binding]; other site
634456001014	Superfamily II DNA and RNA helicases [DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis]; Region: SrmB; COG0513
634456001015	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
634456001016	nucleotide binding region [chemical binding]; other site
634456001017	ATP-binding site [chemical binding]; other site
634456001018	Mitochondrial degradasome RNA helicase subunit C terminal; Region: SUV3_C; pfam12513
634456001019	short chain dehydrogenase; Provisional; Region: PRK06197
634456001020	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
634456001021	NAD(P) binding site [chemical binding]; other site
634456001022	active site
634456001023	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
634456001024	SNARE associated Golgi protein; Region: SNARE_assoc; cl00429
634456001025	Dipeptidyl aminopeptidases/acylaminoacyl-peptidases [Amino acid transport and metabolism]; Region: DAP2; COG1506
634456001026	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
634456001027	malate dehydrogenase; Provisional; Region: PRK13529
634456001028	Malic enzyme, N-terminal domain; Region: malic; pfam00390
634456001029	NAD(P) binding domain of malic enzyme (ME), subgroup 1; Region: NAD_bind_1_malic_enz; cd05312
634456001030	NAD(P) binding site [chemical binding]; other site
634456001031	transcription antitermination protein NusG; Validated; Region: nusG; PRK05609
634456001032	Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1; cd09891
634456001033	putative homodimer interface [polypeptide binding]; other site
634456001034	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
634456001035	heterodimer interface [polypeptide binding]; other site
634456001036	homodimer interface [polypeptide binding]; other site
634456001037	SecE/Sec61-gamma subunits of protein translocation complex; Region: SecE; pfam00584
634456001038	F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein) [Energy production and conversion]; Region: AtpH; COG0712
634456001039	ATP synthase delta (OSCP) subunit; Region: OSCP; pfam00213
634456001040	F0F1 ATP synthase subunit alpha; Validated; Region: PRK09281
634456001041	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
634456001042	F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to...; Region: F1_ATPase_alpha; cd01132
634456001043	beta subunit interaction interface [polypeptide binding]; other site
634456001044	Walker A motif; other site
634456001045	ATP binding site [chemical binding]; other site
634456001046	Walker B motif; other site
634456001047	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
634456001048	mitochondrial ATP synthase gamma subunit; Region: F1-ATPase_gamma; cd12151
634456001049	core domain interface [polypeptide binding]; other site
634456001050	delta subunit interface [polypeptide binding]; other site
634456001051	epsilon subunit interface [polypeptide binding]; other site
634456001052	F0F1 ATP synthase subunit beta; Validated; Region: PRK09280
634456001053	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
634456001054	F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133
634456001055	alpha subunit interaction interface [polypeptide binding]; other site
634456001056	Walker A motif; other site
634456001057	ATP binding site [chemical binding]; other site
634456001058	Walker B motif; other site
634456001059	inhibitor binding site; inhibition site
634456001060	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
634456001061	F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit) [Energy production and conversion]; Region: AtpC; COG0355
634456001062	mitochondrial ATP synthase delta subunit; Region: F1-ATPase_delta; cd12152
634456001063	gamma subunit interface [polypeptide binding]; other site
634456001064	epsilon subunit interface [polypeptide binding]; other site
634456001065	LBP interface [polypeptide binding]; other site
634456001066	7-cyano-7-deazaguanine reductase; Provisional; Region: PRK13258
634456001067	Ribonuclease D [Translation, ribosomal structure and biogenesis]; Region: Rnd; COG0349
634456001068	DEDDy 3'-5' exonuclease domain of Ribonuclease D and similar proteins; Region: RNaseD_exo; cd06142
634456001069	catalytic site [active]
634456001070	putative active site [active]
634456001071	putative substrate binding site [chemical binding]; other site
634456001072	Adenosine kinase (AK) catalyzes the phosphorylation of ribofuranosyl-containing nucleoside analogues at the 5'-hydroxyl using ATP or GTP as the phosphate donor.The physiological function of AK is associated with the regulation of extracellular...; Region: adenosine_kinase; cd01168
634456001073	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
634456001074	substrate binding site [chemical binding]; other site
634456001075	ATP binding site [chemical binding]; other site
634456001076	Polymer-forming cytoskeletal; Region: Bactofilin; pfam04519
634456001077	GcrA cell cycle regulator; Region: GcrA; cl11564
634456001078	GcrA cell cycle regulator; Region: GcrA; cl11564
634456001079	Gamma-aminobutyrate permease and related permeases [Amino acid transport and metabolism]; Region: AnsP; COG1113
634456001080	ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842
634456001081	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
634456001082	Walker A/P-loop; other site
634456001083	ATP binding site [chemical binding]; other site
634456001084	Q-loop/lid; other site
634456001085	ABC transporter signature motif; other site
634456001086	Walker B; other site
634456001087	D-loop; other site
634456001088	H-loop/switch region; other site
634456001089	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
634456001090	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
634456001091	dimer interface [polypeptide binding]; other site
634456001092	conserved gate region; other site
634456001093	putative PBP binding loops; other site
634456001094	ABC-ATPase subunit interface; other site
634456001095	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
634456001096	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
634456001097	dimer interface [polypeptide binding]; other site
634456001098	conserved gate region; other site
634456001099	putative PBP binding loops; other site
634456001100	ABC-ATPase subunit interface; other site
634456001101	Transposase DDE domain group 1; Region: DDE_Tnp_1_4; pfam13701
634456001102	Phosphate-selective porin O and P; Region: Porin_O_P; pfam07396
634456001103	ABC-type sulfate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: Sbp; COG1613
634456001104	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
634456001105	Arabinose-binding domain of AraC transcription regulator, N-term; Region: Arabinose_bd; pfam12625
634456001106	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
634456001107	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
634456001108	ethanolamine ammonia lyase large subunit; Provisional; Region: PRK15067
634456001109	Ethanolamine ammonia lyase large subunit (EutB); Region: EutB; pfam06751
634456001110	ethanolamine ammonia-lyase small subunit; Provisional; Region: PRK05465
634456001111	ethanolamine permease; Region: 2A0305; TIGR00908
634456001112	multidrug efflux system transporter AcrA; Provisional; Region: PRK15030
634456001113	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
634456001114	HlyD family secretion protein; Region: HlyD_3; pfam13437
634456001115	The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Region: 2A0602; TIGR00915
634456001116	Protein export membrane protein; Region: SecD_SecF; cl14618
634456001117	efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family; Region: outer_NodT; TIGR01845
634456001118	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
634456001119	DNA-binding site [nucleotide binding]; DNA binding site
634456001120	RNA-binding motif; other site
634456001121	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
634456001122	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
634456001123	FOG: Transposase [DNA replication, recombination, and repair]; Region: COG5659
634456001124	TonB-dependent siderophore receptor; Region: TonB-siderophor; TIGR01783
634456001125	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
634456001126	N-terminal plug; other site
634456001127	ligand-binding site [chemical binding]; other site
634456001128	hypothetical protein; Provisional; Region: PRK09945
634456001129	Hint domain; Region: Hint_2; pfam13403
634456001130	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
634456001131	formamidase; Provisional; Region: amiF; PRK13287
634456001132	aliphatic amidases (class 2 nitrilases); Region: aliphatic_amidase; cd07565
634456001133	multimer interface [polypeptide binding]; other site
634456001134	active site
634456001135	catalytic triad [active]
634456001136	dimer interface [polypeptide binding]; other site
634456001137	Response regulator receiver domain; Region: Response_reg; pfam00072
634456001138	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
634456001139	active site
634456001140	phosphorylation site [posttranslational modification]
634456001141	intermolecular recognition site; other site
634456001142	dimerization interface [polypeptide binding]; other site
634456001143	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
634456001144	DNA binding residues [nucleotide binding]
634456001145	dimerization interface [polypeptide binding]; other site
634456001146	Solute carrier families 5 and 6-like; solute binding domain; Region: SLC5-6-like_sbd; cl00456
634456001147	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
634456001148	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
634456001149	dimer interface [polypeptide binding]; other site
634456001150	phosphorylation site [posttranslational modification]
634456001151	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
634456001152	ATP binding site [chemical binding]; other site
634456001153	Mg2+ binding site [ion binding]; other site
634456001154	G-X-G motif; other site
634456001155	Response regulator receiver domain; Region: Response_reg; pfam00072
634456001156	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
634456001157	active site
634456001158	phosphorylation site [posttranslational modification]
634456001159	intermolecular recognition site; other site
634456001160	dimerization interface [polypeptide binding]; other site
634456001161	Periplasmic binding protein; Region: Peripla_BP_6; pfam13458
634456001162	Periplasmic component (FmdD) of an active transport system for short-chain amides and urea (FmdDEF); Region: PBP1_FmdD_like; cd06355
634456001163	putative ligand binding site [chemical binding]; other site
634456001164	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
634456001165	Transmembrane subunit (TM) of Escherichia coli LivH and related proteins. LivH is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivH_like; cd06582
634456001166	TM-ABC transporter signature motif; other site
634456001167	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
634456001168	Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivM_like; cd06581
634456001169	TM-ABC transporter signature motif; other site
634456001170	urea ABC transporter, ATP-binding protein UrtD; Region: urea_trans_UrtD; TIGR03411
634456001171	ATP-binding cassette component of branched chain amino acids transport system; Region: ABC_Mj1267_LivG_branched; cd03219
634456001172	Walker A/P-loop; other site
634456001173	ATP binding site [chemical binding]; other site
634456001174	Q-loop/lid; other site
634456001175	ABC transporter signature motif; other site
634456001176	Walker B; other site
634456001177	D-loop; other site
634456001178	H-loop/switch region; other site
634456001179	urea ABC transporter, ATP-binding protein UrtE; Region: urea_trans_UrtE; TIGR03410
634456001180	ATP-binding cassette domain of branched-chain amino acid transporter; Region: ABC_TM1139_LivF_branched; cd03224
634456001181	Walker A/P-loop; other site
634456001182	ATP binding site [chemical binding]; other site
634456001183	Q-loop/lid; other site
634456001184	ABC transporter signature motif; other site
634456001185	Walker B; other site
634456001186	D-loop; other site
634456001187	H-loop/switch region; other site
634456001188	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
634456001189	PD-(D/E)XK nuclease superfamily; Region: PDDEXK_4; pfam14281
634456001190	Predicted transcriptional regulator [Transcription]; Region: COG2378
634456001191	WYL domain; Region: WYL; pfam13280
634456001192	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
634456001193	active site
634456001194	Int/Topo IB signature motif; other site
634456001195	DNA binding site [nucleotide binding]
634456001196	Transposase DDE domain group 1; Region: DDE_Tnp_1_4; pfam13701
634456001197	Bacterial mobilisation protein (MobC); Region: MobC; pfam05713
634456001198	Transposase DDE domain group 1; Region: DDE_Tnp_1_4; pfam13701
634456001199	Serine/threonine protein phosphatase [Signal transduction mechanisms]; Region: PTC1; COG0631
634456001200	active site
634456001201	Catalytic domain of Protein Kinases; Region: PKc; cd00180
634456001202	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
634456001203	active site
634456001204	ATP binding site [chemical binding]; other site
634456001205	substrate binding site [chemical binding]; other site
634456001206	activation loop (A-loop); other site
634456001207	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
634456001208	Catalytic domain of Protein Kinases; Region: PKc; cd00180
634456001209	active site
634456001210	ATP binding site [chemical binding]; other site
634456001211	substrate binding site [chemical binding]; other site
634456001212	activation loop (A-loop); other site
634456001213	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
634456001214	active site
634456001215	Int/Topo IB signature motif; other site
634456001216	DNA binding site [nucleotide binding]
634456001217	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
634456001218	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
634456001219	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
634456001220	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
634456001221	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
634456001222	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
634456001223	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
634456001224	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
634456001225	Transposase; Region: HTH_Tnp_1; pfam01527
634456001226	Protein of unknown function DUF45; Region: DUF45; pfam01863
634456001227	hypothetical protein; Provisional; Region: PRK05170
634456001228	Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416
634456001229	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
634456001230	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
634456001231	ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842
634456001232	Walker A/P-loop; other site
634456001233	ATP binding site [chemical binding]; other site
634456001234	Q-loop/lid; other site
634456001235	ABC transporter signature motif; other site
634456001236	Walker B; other site
634456001237	D-loop; other site
634456001238	H-loop/switch region; other site
634456001239	TOBE domain; Region: TOBE_2; pfam08402
634456001240	Bacterial protein of unknown function (DUF883); Region: DUF883; cl01888
634456001241	Protein of unknown function (DUF1469); Region: DUF1469; pfam07332
634456001242	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
634456001243	Winged helix DNA-binding domain; Region: HTH_27; pfam13463
634456001244	multidrug resistance protein MdtN; Provisional; Region: PRK10476
634456001245	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
634456001246	HlyD family secretion protein; Region: HlyD_3; pfam13437
634456001247	efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family; Region: outer_NodT; TIGR01845
634456001248	hopanoid-associated phosphorylase; Region: HpnG; TIGR03468
634456001249	squalene-hopene cyclase; Region: hopene_cyclase; TIGR01507
634456001250	Squalene cyclase (SQCY) domain subgroup 1; found in class II terpene cyclases that have an alpha 6 - alpha 6 barrel fold. Squalene cyclase (SQCY)  and 2,3-oxidosqualene cyclase (OSQCY) are integral membrane proteins that catalyze a cationic cyclization...; Region: SQCY_1; cd02892
634456001251	Active site cavity [active]
634456001252	catalytic acid [active]
634456001253	squalene-associated FAD-dependent desaturase; Region: HpnE; TIGR03467
634456001254	Trans-Isoprenyl Diphosphate Synthases, head-to-head; Region: Trans_IPPS_HH; cd00683
634456001255	active site lid residues [active]
634456001256	substrate binding pocket [chemical binding]; other site
634456001257	catalytic residues [active]
634456001258	substrate-Mg2+ binding site; other site
634456001259	aspartate-rich region 1; other site
634456001260	aspartate-rich region 2; other site
634456001261	Trans-Isoprenyl Diphosphate Synthases, head-to-head; Region: Trans_IPPS_HH; cd00683
634456001262	active site lid residues [active]
634456001263	substrate binding pocket [chemical binding]; other site
634456001264	catalytic residues [active]
634456001265	substrate-Mg2+ binding site; other site
634456001266	aspartate-rich region 1; other site
634456001267	aspartate-rich region 2; other site
634456001268	hopene-associated glycosyltransferase HpnB; Region: HpnB; TIGR03469
634456001269	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
634456001270	active site
634456001271	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
634456001272	hopanoid-associated sugar epimerase; Region: HpnA; TIGR03466
634456001273	uncharacterized subgroup of aldehyde reductase and flavonoid reductase related proteins, extended (e) SDRs; Region: AR_FR_like_1_SDR_e; cd05228
634456001274	putative NADP binding site [chemical binding]; other site
634456001275	putative substrate binding site [chemical binding]; other site
634456001276	active site
634456001277	Uncharacterized protein family (UPF0104); Region: UPF0104; cl04219
634456001278	cyclohexadienyl dehydrogenase; Validated; Region: PRK07502
634456001279	prephenate dehydrogenase; Validated; Region: PRK08507
634456001280	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
634456001281	TPR motif; other site
634456001282	TPR repeat; Region: TPR_11; pfam13414
634456001283	binding surface
634456001284	Transcriptional regulator [Transcription]; Region: LysR; COG0583
634456001285	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
634456001286	The C-terminal substrate-binding domain of the LysR-type transcriptional regulator OxyR, a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_OxyR; cd08411
634456001287	dimerization interface [polypeptide binding]; other site
634456001288	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
634456001289	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
634456001290	dimer interface [polypeptide binding]; other site
634456001291	decamer (pentamer of dimers) interface [polypeptide binding]; other site
634456001292	catalytic triad [active]
634456001293	peroxidatic and resolving cysteines [active]
634456001294	alkylhydroperoxidase, AhpD family; Region: ahpD; TIGR00777
634456001295	alkylhydroperoxidase AhpD family core domain; Region: ahpD_dom; TIGR00778
634456001296	Uncharacterized conserved protein [Function unknown]; Region: COG2353
634456001297	The Class III extradiol dioxygenase, 4,5-DOPA Dioxygenase, catalyzes the incorporation of both atoms of molecular oxygen into 4,5-dihydroxy-phenylalanine; Region: 45_DOPA_Dioxygenase; cd07363
634456001298	Catalytic LigB subunit of aromatic ring-opening dioxygenase; Region: LigB; pfam02900
634456001299	putative active site [active]
634456001300	metal binding site [ion binding]; metal-binding site
634456001301	Inorganic pyrophosphatase. These enzymes hydrolyze inorganic pyrophosphate (PPi) to two molecules of orthophosphates (Pi). The reaction requires bivalent cations. The enzymes in general exist as homooligomers; Region: pyrophosphatase; cd00412
634456001302	dimer interface [polypeptide binding]; other site
634456001303	substrate binding site [chemical binding]; other site
634456001304	metal binding sites [ion binding]; metal-binding site
634456001305	putative ABC transporter ATP-binding protein; Reviewed; Region: PRK11819
634456001306	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
634456001307	Walker A/P-loop; other site
634456001308	ATP binding site [chemical binding]; other site
634456001309	Q-loop/lid; other site
634456001310	ABC transporter signature motif; other site
634456001311	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
634456001312	ABC transporter; Region: ABC_tran_2; pfam12848
634456001313	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
634456001314	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
634456001315	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
634456001316	Coenzyme A binding pocket [chemical binding]; other site
634456001317	Toluene tolerance, Ttg2; Region: Tol_Tol_Ttg2; pfam05494
634456001318	VacJ like lipoprotein; Region: VacJ; cl01073
634456001319	N-terminal tellurium resistance protein terB-like domain of heat shock DnaJ-like proteins; Region: terB_like_DjlA; cd07316
634456001320	putative metal binding site [ion binding]; other site
634456001321	DnaJ-domain-containing proteins 1 [Posttranslational modification, protein turnover, chaperones]; Region: DjlA; COG1076
634456001322	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
634456001323	HSP70 interaction site [polypeptide binding]; other site
634456001324	Ribbon-helix-helix domain; Region: RHH_4; pfam13467
634456001325	epoxyqueuosine reductase; Region: TIGR00276
634456001326	Domain of unknown function (DUF1730); Region: DUF1730; pfam08331
634456001327	queuine tRNA-ribosyltransferase; Provisional; Region: tgt; PRK00112
634456001328	Queuine/archaeosine tRNA-ribosyltransferase [Translation, ribosomal structure and biogenesis]; Region: Tgt; COG0343
634456001329	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Region: queA; TIGR00113
634456001330	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Provisional; Region: queA; PRK00147
634456001331	PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in bacteria and archaea; Region: PEBP_bact_arch; cd00865
634456001332	substrate binding site [chemical binding]; other site
634456001333	Methylenetetrahydrofolate reductase (MTHFR). 5,10-Methylenetetrahydrofolate is reduced to 5-methyltetrahydrofolate by methylenetetrahydrofolate reductase, a cytoplasmic, NAD(P)-dependent enzyme. 5-methyltetrahydrofolate is utilized by methionine synthase...; Region: MTHFR; cl00246
634456001334	FAD binding site [chemical binding]; other site
634456001335	bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase; Provisional; Region: PRK14188
634456001336	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763
634456001337	NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080
634456001338	homodimer interface [polypeptide binding]; other site
634456001339	NADP binding site [chemical binding]; other site
634456001340	substrate binding site [chemical binding]; other site
634456001341	Acetyltransferase (GNAT) domain; Region: Acetyltransf_6; cl17497
634456001342	Protein of unknown function, DUF482; Region: DUF482; pfam04339
634456001343	This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function.  The conserved domain is similar in structure to chorismate mutase but there is no sequence...; Region: YjgF_YER057c_UK114_like_1; cd02199
634456001344	homotrimer interaction site [polypeptide binding]; other site
634456001345	putative active site [active]
634456001346	TSCPD domain; Region: TSCPD; pfam12637
634456001347	NADH dehydrogenase; Validated; Region: PRK08183
634456001348	ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2C; COG1463
634456001349	mce related protein; Region: MCE; pfam02470
634456001350	Uncharacterized protein conserved in bacteria (DUF2155); Region: DUF2155; cl01970
634456001351	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
634456001352	Trehalose-phosphatase; Region: Trehalose_PPase; pfam02358
634456001353	active site
634456001354	motif I; other site
634456001355	motif II; other site
634456001356	alpha,alpha-trehalose-phosphate synthase [UDP-forming]; Region: trehalose_OtsA; TIGR02400
634456001357	Trehalose-6-Phosphate Synthase (TPS) is a glycosyltransferase that catalyses the synthesis of alpha,alpha-1,1-trehalose-6-phosphate from glucose-6-phosphate using a UDP-glucose donor. It is a key enzyme in the trehalose synthesis pathway. Trehalose is a...; Region: GT1_TPS; cd03788
634456001358	active site
634456001359	homotetramer interface [polypeptide binding]; other site
634456001360	Disulfide bond formation protein DsbB; Region: DsbB; pfam02600
634456001361	Predicted glycosyltransferases [General function prediction only]; Region: COG1216
634456001362	Subfamily of Glycosyltransferase Family GT2 of unknown function; Region: GT_2_like_c; cd04186
634456001363	Probable Catalytic site; other site
634456001364	metal-binding site
634456001365	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
634456001366	Glycosyl transferases group 1; Region: Glyco_trans_1_4; pfam13692
634456001367	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_15; cd04673
634456001368	nudix motif; other site
634456001369	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
634456001370	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
634456001371	active site
634456001372	catalytic tetrad [active]
634456001373	Helix-turn-helix domain; Region: HTH_17; pfam12728
634456001374	excinuclease ABC subunit B; Provisional; Region: PRK05298
634456001375	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
634456001376	ATP binding site [chemical binding]; other site
634456001377	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
634456001378	nucleotide binding region [chemical binding]; other site
634456001379	ATP-binding site [chemical binding]; other site
634456001380	Ultra-violet resistance protein B; Region: UvrB; pfam12344
634456001381	UvrB/uvrC motif; Region: UVR; pfam02151
634456001382	2OG-Fe(II) oxygenase superfamily; Region: 2OG-FeII_Oxy_3; pfam13640
634456001383	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
634456001384	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
634456001385	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
634456001386	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
634456001387	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
634456001388	haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; Region: HAD-SF-IA-v3; TIGR01509
634456001389	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
634456001390	active site
634456001391	motif I; other site
634456001392	motif II; other site
634456001393	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
634456001394	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
634456001395	active site
634456001396	L-asparagine permease; Provisional; Region: PRK15049
634456001397	DNA Polymerase IV/Kappa; Region: PolY_Pol_IV_kappa; cd03586
634456001398	active site
634456001399	DNA polymerase IV; Validated; Region: PRK02406
634456001400	DNA binding site [nucleotide binding]
634456001401	Aspartyl/asparaginyl beta-hydroxylase and related dioxygenases [Posttranslational modification, protein turnover, chaperones]; Region: COG3555
634456001402	dihydroorotate dehydrogenase 2; Reviewed; Region: PRK05286
634456001403	Dihydroorotate dehydrogenase (DHOD) class 2. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine nucleotides. DHOD requires...; Region: DHOD_2_like; cd04738
634456001404	quinone interaction residues [chemical binding]; other site
634456001405	active site
634456001406	catalytic residues [active]
634456001407	FMN binding site [chemical binding]; other site
634456001408	substrate binding site [chemical binding]; other site
634456001409	HAD-superfamily class IIA hydrolase, TIGR01459; Region: HAD-SF-IIA-hyp4
634456001410	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
634456001411	active site
634456001412	motif I; other site
634456001413	motif II; other site
634456001414	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
634456001415	Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cl00447
634456001416	nudix motif; other site
634456001417	Deinococcus radiodurans DR1281 and related proteins, metallophosphatase domain; Region: MPP_DR1281; cd07382
634456001418	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
634456001419	putative active site [active]
634456001420	metal binding site [ion binding]; metal-binding site
634456001421	homodimer binding site [polypeptide binding]; other site
634456001422	5-formyltetrahydrofolate cyclo-ligase family; Region: 5-FTHF_cyc-lig; pfam01812
634456001423	5,10-methenyltetrahydrofolate synthetase; Region: MTHFS_bact; TIGR02727
634456001424	Cell division protein ZapA; Region: ZapA; cl01146
634456001425	fructose-bisphosphate aldolase; Provisional; Region: PRK09250
634456001426	Class I fructose-1,6-bisphosphate (FBP) aldolases of the archaeal type (DhnA homologs); Region: DhnA; cd00958
634456001427	putative active site; other site
634456001428	catalytic residue [active]
634456001429	Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-; Region: TMP_TenI; cd00564
634456001430	thiamine phosphate binding site [chemical binding]; other site
634456001431	active site
634456001432	pyrophosphate binding site [ion binding]; other site
634456001433	Prophage antirepressor [Transcription]; Region: COG3617
634456001434	BRO family, N-terminal domain; Region: Bro-N; smart01040
634456001435	Phage antirepressor protein KilAC domain; Region: ANT; pfam03374
634456001436	Domain of unknown function (DUF4160); Region: DUF4160; pfam13711
634456001437	Protein of unknown function (DUF2442); Region: DUF2442; pfam10387
634456001438	Transposase DDE domain group 1; Region: DDE_Tnp_1_4; pfam13701
634456001439	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3464
634456001440	Transposase; Region: DDE_Tnp_ISL3; pfam01610
634456001441	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
634456001442	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
634456001443	Transposase; Region: DDE_Tnp_ISL3; pfam01610
634456001444	Protein of unknown function (DUF2501); Region: DUF2501; cl08197
634456001445	Fasciclin domain; Region: Fasciclin; cl02663
634456001446	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
634456001447	EF-P lysine aminoacylase GenX; Region: genX; TIGR00462
634456001448	motif 1; other site
634456001449	dimer interface [polypeptide binding]; other site
634456001450	active site
634456001451	motif 2; other site
634456001452	motif 3; other site
634456001453	Radical SAM superfamily; Region: Radical_SAM; pfam04055
634456001454	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
634456001455	FeS/SAM binding site; other site
634456001456	Lysine-2,3-aminomutase; Region: LAM_C; pfam12544
634456001457	Gamma-glutamyltransferase [Amino acid transport and metabolism]; Region: Ggt; COG0405
634456001458	Gamma-glutamyltranspeptidase; Region: G_glu_transpept; pfam01019
634456001459	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
634456001460	active site
634456001461	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
634456001462	D-alanyl-D-alanine carboxypeptidase; Region: Peptidase_S11; pfam00768
634456001463	Uncharacterized conserved protein [Function unknown]; Region: COG2127
634456001464	ATP-dependent Clp protease ATP-binding subunit clpA; Region: ClpA; TIGR02639
634456001465	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
634456001466	Walker A motif; other site
634456001467	ATP binding site [chemical binding]; other site
634456001468	Walker B motif; other site
634456001469	arginine finger; other site
634456001470	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
634456001471	Walker A motif; other site
634456001472	ATP binding site [chemical binding]; other site
634456001473	Walker B motif; other site
634456001474	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
634456001475	Protein of unknown function (DUF3465); Region: DUF3465; pfam11948
634456001476	polyphosphate:nucleotide phosphotransferase, PPK2 family; Region: PPK2_rel_1; TIGR03709
634456001477	Putative transcriptional regulator [Transcription]; Region: COG1678
634456001478	glmZ(sRNA)-inactivating NTPase; Provisional; Region: PRK05416
634456001479	Shikimate kinase; Region: SKI; pfam01202
634456001480	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cl10015
634456001481	homotrimer interaction site [polypeptide binding]; other site
634456001482	putative active site [active]
634456001483	Sensor N-terminal transmembrane domain; Region: Sensor_TM1; pfam13755
634456001484	Stimulus-sensing domain; Region: Stimulus_sens_1; pfam13756
634456001485	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
634456001486	HAMP domain; Region: HAMP; pfam00672
634456001487	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
634456001488	dimer interface [polypeptide binding]; other site
634456001489	phosphorylation site [posttranslational modification]
634456001490	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
634456001491	ATP binding site [chemical binding]; other site
634456001492	Mg2+ binding site [ion binding]; other site
634456001493	G-X-G motif; other site
634456001494	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
634456001495	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
634456001496	active site
634456001497	phosphorylation site [posttranslational modification]
634456001498	intermolecular recognition site; other site
634456001499	dimerization interface [polypeptide binding]; other site
634456001500	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
634456001501	DNA binding site [nucleotide binding]
634456001502	GrpE; Region: GrpE; pfam01025
634456001503	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446
634456001504	dimer interface [polypeptide binding]; other site
634456001505	hsp70 (ATPase domain) interactions [polypeptide binding]; other site
634456001506	molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290
634456001507	Nucleotide-binding domain of human HSPA9, Escherichia coli DnaK, and similar proteins; Region: HSPA9-like_NBD; cd11733
634456001508	nucleotide binding site [chemical binding]; other site
634456001509	NEF interaction site [polypeptide binding]; other site
634456001510	SBD interface [polypeptide binding]; other site
634456001511	chaperone protein DnaJ; Provisional; Region: PRK10767
634456001512	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
634456001513	HSP70 interaction site [polypeptide binding]; other site
634456001514	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
634456001515	Zn binding sites [ion binding]; other site
634456001516	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
634456001517	dimer interface [polypeptide binding]; other site
634456001518	dihydrodipicolinate reductase; Provisional; Region: PRK00048
634456001519	Dihydrodipicolinate reductase, N-terminus; Region: DapB_N; pfam01113
634456001520	Dihydrodipicolinate reductase, C-terminus; Region: DapB_C; pfam05173
634456001521	S-adenosylmethionine synthetase; Validated; Region: PRK05250
634456001522	S-adenosylmethionine synthetase, N-terminal domain; Region: S-AdoMet_synt_N; pfam00438
634456001523	S-adenosylmethionine synthetase, central domain; Region: S-AdoMet_synt_M; pfam02772
634456001524	S-adenosylmethionine synthetase, C-terminal domain; Region: S-AdoMet_synt_C; pfam02773
634456001525	tRNA (guanine-N(7)-)-methyltransferase; Reviewed; Region: trmB; PRK00121
634456001526	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional; Region: purH; PRK00881
634456001527	Inosine monophosphate cyclohydrolase domain. This is the N-terminal domain in the purine biosynthesis pathway protein ATIC (purH). The bifunctional ATIC protein contains a C-terminal  ATIC formylase domain that formylates...; Region: IMPCH; cd01421
634456001528	purine monophosphate binding site [chemical binding]; other site
634456001529	dimer interface [polypeptide binding]; other site
634456001530	putative catalytic residues [active]
634456001531	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; smart00798
634456001532	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
634456001533	EamA-like transporter family; Region: EamA; pfam00892
634456001534	glycyl-tRNA synthetase subunit beta; Validated; Region: glyS; PRK01233
634456001535	DALR anticodon binding domain; Region: DALR_1; pfam05746
634456001536	Class II Glycyl-tRNA synthetase (GlyRS) alpha subunit core catalytic domain. GlyRS functions as a homodimer in eukaryotes, archaea and some bacteria and as a heterotetramer in the remainder of prokaryotes and in arabidopsis. It is responsible for the...; Region: GlyRS_alpha_core; cd00733
634456001537	dimer interface [polypeptide binding]; other site
634456001538	motif 1; other site
634456001539	active site
634456001540	motif 2; other site
634456001541	motif 3; other site
634456001542	Uncharacterized protein conserved in bacteria (DUF2076); Region: DUF2076; pfam09849
634456001543	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
634456001544	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
634456001545	non-specific DNA binding site [nucleotide binding]; other site
634456001546	salt bridge; other site
634456001547	sequence-specific DNA binding site [nucleotide binding]; other site
634456001548	apolipoprotein N-acyltransferase; Region: lnt; TIGR00546
634456001549	Apolipoprotein N-acyl transferase (class 9 nitrilases); Region: ALP_N-acyl_transferase; cd07571
634456001550	putative active site [active]
634456001551	catalytic triad [active]
634456001552	putative dimer interface [polypeptide binding]; other site
634456001553	Acetyltransferase (GNAT) domain; Region: Acetyltransf_5; cl17496
634456001554	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
634456001555	metal binding site 2 [ion binding]; metal-binding site
634456001556	putative DNA binding helix; other site
634456001557	metal binding site 1 [ion binding]; metal-binding site
634456001558	dimer interface [polypeptide binding]; other site
634456001559	structural Zn2+ binding site [ion binding]; other site
634456001560	SirA, YedF, and YeeD. Two-layered alpha/beta sandwich domain.  SirA (also known as UvrY,  and YhhP) belongs to a family of bacterial two-component response regulators that controls secondary metabolism and virulence. The other member of this...; Region: SirA_YedF_YeeD; cd00291
634456001561	CPxP  motif; other site
634456001562	transcription termination factor Rho; Provisional; Region: rho; PRK09376
634456001563	Rho termination factor, N-terminal domain; Region: Rho_N; pfam07498
634456001564	Rho_CSD: Rho protein cold-shock domain (CSD). Rho protein is a transcription termination factor in most bacteria. In bacteria, there are two distinct mechanisms for mRNA transcription termination. In intrinsic termination, RNA polymerase and nascent mRNA...; Region: Rho_CSD; cd04459
634456001565	RNA binding site [nucleotide binding]; other site
634456001566	Transcription termination factor rho is a bacterial ATP-dependent RNA/DNA helicase. It is a homohexamer. Each monomer consists of an N-terminal domain of the OB fold, which is responsible for binding to cysteine rich nucleotides. This alignment is of the...; Region: rho_factor; cd01128
634456001567	multimer interface [polypeptide binding]; other site
634456001568	Walker A motif; other site
634456001569	ATP binding site [chemical binding]; other site
634456001570	Walker B motif; other site
634456001571	uncharacterized subgroup of the Escherichia coli Mg2+ transporter CorA_like subfamily; Region: EcCorA-like_u1; cd12837
634456001572	CorA-like Mg2+ transporter protein; Region: CorA; pfam01544
634456001573	oligomer interface [polypeptide binding]; other site
634456001574	Cl binding site [ion binding]; other site
634456001575	tryptophan synthase, beta subunit; Region: trpB; TIGR00263
634456001576	Tryptophan synthase-beta:  Trptophan synthase is a bifunctional enzyme that catalyses the last two steps in the biosynthesis of L-tryptophan via its alpha and beta reactions. In the alpha reaction, indole 3-glycerol phosphate is cleaved reversibly to...; Region: Trp-synth_B; cd06446
634456001577	pyridoxal 5'-phosphate binding site [chemical binding]; other site
634456001578	catalytic residue [active]
634456001579	Ttryptophan synthase (TRPS) alpha subunit (TSA). TPRS is a bifunctional tetrameric enzyme (2 alpha and 2 beta subunits) that catalyzes the last two steps of L-tryptophan biosynthesis. Alpha and beta subunit catalyze two distinct reactions which are both...; Region: Tryptophan_synthase_alpha; cd04724
634456001580	substrate binding site [chemical binding]; other site
634456001581	active site
634456001582	catalytic residues [active]
634456001583	heterodimer interface [polypeptide binding]; other site
634456001584	uncharacterized flavoprotein, PP_4765 family; Region: flavo_PP4765; TIGR03862
634456001585	HerA helicase [Replication, recombination, and repair]; Region: COG0433
634456001586	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
634456001587	Walker A motif; other site
634456001588	ATP binding site [chemical binding]; other site
634456001589	Walker B motif; other site
634456001590	Histidyl-tRNA synthetase; Region: tRNA-synt_His; pfam13393
634456001591	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
634456001592	dimer interface [polypeptide binding]; other site
634456001593	motif 1; other site
634456001594	active site
634456001595	motif 2; other site
634456001596	motif 3; other site
634456001597	Adenylosuccinate synthetase; Region: Adenylsucc_synt; smart00788
634456001598	Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the...; Region: AdSS; cd03108
634456001599	GDP-binding site [chemical binding]; other site
634456001600	ACT binding site; other site
634456001601	IMP binding site; other site
634456001602	phosphate regulon transcriptional regulatory protein PhoB; Region: PhoB; TIGR02154
634456001603	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
634456001604	active site
634456001605	phosphorylation site [posttranslational modification]
634456001606	intermolecular recognition site; other site
634456001607	dimerization interface [polypeptide binding]; other site
634456001608	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
634456001609	DNA binding site [nucleotide binding]
634456001610	phosphate regulon sensor kinase PhoR; Region: phoR_proteo; TIGR02966
634456001611	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
634456001612	dimer interface [polypeptide binding]; other site
634456001613	phosphorylation site [posttranslational modification]
634456001614	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
634456001615	ATP binding site [chemical binding]; other site
634456001616	Mg2+ binding site [ion binding]; other site
634456001617	G-X-G motif; other site
634456001618	PBP superfamily domain; Region: PBP_like_2; cl17296
634456001619	Phosphate-selective porin O and P; Region: Porin_O_P; pfam07396
634456001620	Glycine-zipper containing OmpA-like membrane domain; Region: Gly-zipper_OmpA; pfam13436
634456001621	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
634456001622	Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction; Region: HP_HAP_like; cd07061
634456001623	catalytic core [active]
634456001624	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
634456001625	Domain of unknown function DUF21; Region: DUF21; pfam01595
634456001626	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
634456001627	Transporter associated domain; Region: CorC_HlyC; smart01091
634456001628	Yhdh putative quinone oxidoreductases; Region: MDR_yhdh; cd08288
634456001629	putative quinone oxidoreductase, YhdH/YhfP family; Region: oxido_YhdH; TIGR02823
634456001630	NADP binding site [chemical binding]; other site
634456001631	dimer interface [polypeptide binding]; other site
634456001632	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms]; Region: SunT; COG2274
634456001633	A sub-family of peptidase family C39. Peptidase family C39 mostly contains bacteriocin-processing endopeptidases from bacteria. The cysteine peptidases in family C39 cleave the "double-glycine" leader peptides from the precursors of various...; Region: Peptidase_C39C; cd02419
634456001634	putative active site [active]
634456001635	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
634456001636	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
634456001637	Walker A/P-loop; other site
634456001638	ATP binding site [chemical binding]; other site
634456001639	Q-loop/lid; other site
634456001640	ABC transporter signature motif; other site
634456001641	Walker B; other site
634456001642	D-loop; other site
634456001643	H-loop/switch region; other site
634456001644	type I secretion membrane fusion protein, HlyD family; Region: type_I_hlyD; TIGR01843
634456001645	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
634456001646	HlyD family secretion protein; Region: HlyD_3; pfam13437
634456001647	Hint domain; Region: Hint_2; pfam13403
634456001648	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557
634456001649	classical (c) SDRs; Region: SDR_c; cd05233
634456001650	NAD(P) binding site [chemical binding]; other site
634456001651	active site
634456001652	N-acetyl-gamma-glutamyl-phosphate reductase; Provisional; Region: PRK11863
634456001653	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
634456001654	nucleoside triphosphate pyrophosphohydrolase; Reviewed; Region: mazG; PRK09562
634456001655	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) N-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs; Region: NTP-PPase_MazG_Nterm; cd11528
634456001656	homodimer interface [polypeptide binding]; other site
634456001657	metal binding site [ion binding]; metal-binding site
634456001658	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) C-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs' Region: NTP-PPase_MazG_Cterm; cd11529
634456001659	homodimer interface [polypeptide binding]; other site
634456001660	active site
634456001661	putative chemical substrate binding site [chemical binding]; other site
634456001662	metal binding site [ion binding]; metal-binding site
634456001663	Protein of unknown function (DUF2501); Region: DUF2501; cl08197
634456001664	heat shock protein 90; Provisional; Region: PRK05218
634456001665	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
634456001666	ATP binding site [chemical binding]; other site
634456001667	Mg2+ binding site [ion binding]; other site
634456001668	G-X-G motif; other site
634456001669	N-formylglutamate amidohydrolase; Region: FGase; pfam05013
634456001670	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
634456001671	DNA binding site [nucleotide binding]
634456001672	active site
634456001673	Int/Topo IB signature motif; other site
634456001674	Chaperone of endosialidase; Region: Peptidase_S74; pfam13884
634456001675	Transposase DDE domain group 1; Region: DDE_Tnp_1_4; pfam13701
634456001676	CotH protein; Region: CotH; pfam08757
634456001677	Putative papain-like cysteine peptidase (DUF1796); Region: DUF1796; pfam08795
634456001678	Glycosyltransferase sugar-binding region containing DXD motif; Region: Gly_transf_sug; pfam04488
634456001679	Predicted acyltransferases [Lipid metabolism]; Region: COG1835
634456001680	DNA/RNA non-specific endonuclease; prokaryotic and eukaryotic double- and single-stranded DNA and RNA endonucleases also present in phosphodiesterases.  They exists as monomers and homodimers; Region: NUC; cd00091
634456001681	DNA/RNA non-specific endonuclease; Region: Endonuclease_NS; smart00892
634456001682	active site
634456001683	substrate binding site [chemical binding]; other site
634456001684	Mg2+ binding site [ion binding]; other site
634456001685	hypothetical protein; Provisional; Region: PRK09272
634456001686	hypothetical protein; Provisional; Region: PRK10316
634456001687	YfdX protein; Region: YfdX; pfam10938
634456001688	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
634456001689	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
634456001690	sequence-specific DNA binding site [nucleotide binding]; other site
634456001691	salt bridge; other site
634456001692	Predicted transcriptional regulator [General function prediction only]; Region: COG3800
634456001693	Domain of unknown function (DUF955); Region: DUF955; pfam06114
634456001694	Predicted transcriptional regulator (DUF2083); Region: DUF2083; pfam09856
634456001695	Uncharacterized protein involved in propionate catabolism [General function prediction only]; Region: PrpD; COG2079
634456001696	Citrate synthase [Energy production and conversion]; Region: GltA; COG0372
634456001697	methylcitrate synthase; Provisional; Region: PRK12351
634456001698	oxalacetate binding site [chemical binding]; other site
634456001699	citrylCoA binding site [chemical binding]; other site
634456001700	coenzyme A binding site [chemical binding]; other site
634456001701	catalytic triad [active]
634456001702	Phosphoenolpyruvate phosphomutase; Region: PEP_mutase; pfam13714
634456001703	Members of the ICL/PEPM enzyme family catalyze either P-C or C-C bond formation/cleavage. Known members are phosphoenolpyruvate mutase (PEPM), phosphonopyruvate hydrolase (PPH), carboxyPEP mutase (CPEP mutase), oxaloacetate hydrolase (OAH), isocitrate...; Region: ICL_PEPM; cd00377
634456001704	tetramer interface [polypeptide binding]; other site
634456001705	active site
634456001706	Mg2+/Mn2+ binding site [ion binding]; other site
634456001707	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
634456001708	acetyl-CoA synthetase; Provisional; Region: PRK00174
634456001709	acyl-activating enzyme (AAE) consensus motif; other site
634456001710	AMP binding site [chemical binding]; other site
634456001711	active site
634456001712	CoA binding site [chemical binding]; other site
634456001713	putative sialic acid transporter; Region: 2A0112; TIGR00891
634456001714	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
634456001715	putative substrate translocation pore; other site
634456001716	Protein of unknown function (DUF1643); Region: DUF1643; pfam07799
634456001717	Thermophilic metalloprotease (M29); Region: Peptidase_M29; pfam02073
634456001718	Leucyl aminopeptidase (aminopeptidase T) [Amino acid transport and metabolism]; Region: AmpS; COG2309
634456001719	Domain of unknown function (DUF1849); Region: DUF1849; pfam08904
634456001720	aspartyl-tRNA synthetase; Validated; Region: aspS; PRK00476
634456001721	EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; Region: EcAspRS_like_N; cd04317
634456001722	dimer interface [polypeptide binding]; other site
634456001723	anticodon binding site; other site
634456001724	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
634456001725	homodimer interface [polypeptide binding]; other site
634456001726	motif 1; other site
634456001727	active site
634456001728	motif 2; other site
634456001729	GAD domain; Region: GAD; pfam02938
634456001730	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
634456001731	active site
634456001732	motif 3; other site
634456001733	Threonine aldolase [Amino acid transport and metabolism]; Region: GLY1; COG2008
634456001734	Low-specificity threonine aldolase (TA). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I).  TA catalyzes the conversion of L-threonine or L-allo-threonine to glycine and acetaldehyde in a...; Region: TA_like; cd06502
634456001735	tetramer interface [polypeptide binding]; other site
634456001736	pyridoxal 5'-phosphate binding site [chemical binding]; other site
634456001737	catalytic residue [active]
634456001738	50S ribosomal protein L25/general stress protein Ctc; Reviewed; Region: PRK05618
634456001739	Ribosomal L25/TL5/CTC N-terminal 5S rRNA binding domain; Region: Ribosomal_L25_TL5_CTC; cd00495
634456001740	5S rRNA interface [nucleotide binding]; other site
634456001741	CTC domain interface [polypeptide binding]; other site
634456001742	L16 interface [polypeptide binding]; other site
634456001743	Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462
634456001744	putative active site [active]
634456001745	catalytic residue [active]
634456001746	GTP-binding protein YchF; Reviewed; Region: PRK09601
634456001747	YchF GTPase; Region: YchF; cd01900
634456001748	G1 box; other site
634456001749	GTP/Mg2+ binding site [chemical binding]; other site
634456001750	Switch I region; other site
634456001751	G2 box; other site
634456001752	Switch II region; other site
634456001753	G3 box; other site
634456001754	G4 box; other site
634456001755	G5 box; other site
634456001756	TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867
634456001757	Gamma-glutamyl phosphate reductase (GPR), aldehyde dehydrogenase families 18 and 19; Region: ALDH_F18-19_ProA-GPR; cd07079
634456001758	gamma-glutamyl phosphate reductase; Region: proA; TIGR00407
634456001759	putative catalytic cysteine [active]
634456001760	Nicotinamide/nicotinate mononucleotide adenylyltransferase; Region: NMNAT; cd02165
634456001761	Cytidylyltransferase; Region: CTP_transf_2; pfam01467
634456001762	active site
634456001763	(T/H)XGH motif; other site
634456001764	iojap-like ribosome-associated protein; Region: iojap_ybeB; TIGR00090
634456001765	rRNA large subunit methyltransferase; Provisional; Region: PRK00103
634456001766	Rhodanese-related sulfurtransferase [Inorganic ion transport and metabolism]; Region: SseA; COG2897
634456001767	Rhodanese-like domain; Region: Rhodanese; pfam00581
634456001768	active site residue [active]
634456001769	Thiosulfate sulfurtransferase (TST), C-terminal, catalytic domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the second repeat. Only the second repeat contains the catalytically active Cys residue; Region: TST_Repeat_2; cd01449
634456001770	active site residue [active]
634456001771	Transcriptional regulator [Transcription]; Region: LysR; COG0583
634456001772	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
634456001773	The C-terminal substrate binding domain of LysR-type transcrptional regulator BudR, which is responsible for activation of the expression of the butanediol operon genes; contains the type 2 periplasmic binding fold; Region: PBP2_BudR; cd08451
634456001774	putative dimerization interface [polypeptide binding]; other site
634456001775	putative substrate binding pocket [chemical binding]; other site
634456001776	Alpha-acetolactate decarboxylase; Region: AAL_decarboxy; pfam03306
634456001777	acetolactate synthase; Reviewed; Region: PRK08617
634456001778	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
634456001779	PYR/PP interface [polypeptide binding]; other site
634456001780	dimer interface [polypeptide binding]; other site
634456001781	TPP binding site [chemical binding]; other site
634456001782	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
634456001783	Thiamine pyrophosphate (TPP) enzyme family, TPP-binding module; found in many key metabolic enzymes which use TPP (also known as thiamine diphosphate) as a cofactor. These enzymes include, among others, the E1 components of the pyruvate, the acetoin and...; Region: TPP_enzymes; cl01629
634456001784	TPP-binding site [chemical binding]; other site
634456001785	benzoylformate decarboxylase; Reviewed; Region: PRK07092
634456001786	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
634456001787	PYR/PP interface [polypeptide binding]; other site
634456001788	dimer interface [polypeptide binding]; other site
634456001789	TPP binding site [chemical binding]; other site
634456001790	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
634456001791	Thiamine pyrophosphate (TPP) family, BFDC subfamily, TPP-binding module; composed of proteins similar to Pseudomonas putida benzoylformate decarboxylase (BFDC). P. putida BFDC plays a role in the mandelate pathway, catalyzing the conversion of...; Region: TPP_BFDC; cd02002
634456001792	TPP-binding site [chemical binding]; other site
634456001793	dimer interface [polypeptide binding]; other site
634456001794	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
634456001795	Cysteine-rich domain; Region: CCG; pfam02754
634456001796	Cysteine-rich domain; Region: CCG; pfam02754
634456001797	Uncharacterized conserved protein containing a ferredoxin-like domain [Energy production and conversion]; Region: COG1139
634456001798	Uncharacterized ACR, YkgG family COG1556; Region: DUF162; pfam02589
634456001799	4Fe-4S binding domain; Region: Fer4; pfam00037
634456001800	Uncharacterized ACR, YkgG family COG1556; Region: DUF162; pfam02589
634456001801	Multidrug resistance efflux transporter; Region: EmrE; pfam13536
634456001802	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
634456001803	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
634456001804	hinge; other site
634456001805	active site
634456001806	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
634456001807	trimer interface [polypeptide binding]; other site
634456001808	active site
634456001809	Carbohydrate-selective porin, OprB family; Region: OprB; pfam04966
634456001810	hopanoid biosynthesis associated protein HpnK and similar proteins; Region: YdjC_HpnK_like; cd10804
634456001811	putative active site [active]
634456001812	YdjC motif; other site
634456001813	Mg binding site [ion binding]; other site
634456001814	putative homodimer interface [polypeptide binding]; other site
634456001815	hopanoid biosynthesis associated radical SAM protein HpnJ; Region: HpnJ; TIGR03471
634456001816	B12 binding domain (B12-BD). Most of the members bind different cobalamid derivates, like B12 (adenosylcobamide) or methylcobalamin or methyl-Co(III) 5-hydroxybenzimidazolylcobamide. This domain is found in several enzymes, such as glutamate mutase; Region: B12-binding_like; cl00293
634456001817	B12 binding site [chemical binding]; other site
634456001818	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
634456001819	FeS/SAM binding site; other site
634456001820	hopanoid biosynthesis associated glycosyl transferase protein HpnI; Region: HpnI; TIGR03472
634456001821	Glucosylceramide synthase catalyzes the first glycosylation step of glycosphingolipid synthesis; Region: Glucosylceramide_synthase; cd02520
634456001822	ligand binding site; other site
634456001823	Toluene tolerance, Ttg2; Region: Tol_Tol_Ttg2; cl01074
634456001824	1-deoxy-D-xylulose-5-phosphate synthase; Provisional; Region: PRK05444
634456001825	Thiamine pyrophosphate (TPP) family, DXS subfamily, TPP-binding module; 1-Deoxy-D-xylulose-5-phosphate synthase (DXS) is a regulatory enzyme of the mevalonate-independent pathway involved in terpenoid biosynthesis. Terpeniods are plant natural products...; Region: TPP_DXS; cd02007
634456001826	TPP-binding site; other site
634456001827	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
634456001828	PYR/PP interface [polypeptide binding]; other site
634456001829	dimer interface [polypeptide binding]; other site
634456001830	TPP binding site [chemical binding]; other site
634456001831	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
634456001832	hopanoid biosynthesis associated radical SAM protein HpnH; Region: HpnH; TIGR03470
634456001833	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
634456001834	FeS/SAM binding site; other site
634456001835	DRE-TIM metallolyase superfamily; Region: DRE_TIM_metallolyase; cl07974
634456001836	Domain of unknown function (DUF3463); Region: DUF3463; pfam11946
634456001837	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
634456001838	Domain of unknown function DUF21; Region: DUF21; pfam01595
634456001839	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
634456001840	Transporter associated domain; Region: CorC_HlyC; smart01091
634456001841	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
634456001842	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
634456001843	N-acetyl-D-glucosamine binding site [chemical binding]; other site
634456001844	catalytic residue [active]
634456001845	Family 4 Uracil-DNA glycosylase (UDG), found exclusively in thermophilic organisms; Region: UDG_F4_TTUDGA_like; cd10030
634456001846	Fe-S cluster binding site [ion binding]; other site
634456001847	active site
634456001848	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
634456001849	binding surface
634456001850	TPR motif; other site
634456001851	Tetratricopeptide repeat; Region: TPR_12; pfam13424
634456001852	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
634456001853	TPR motif; other site
634456001854	TPR repeat; Region: TPR_11; pfam13414
634456001855	binding surface
634456001856	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Provisional; Region: PRK14608
634456001857	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
634456001858	NAD(P) binding site [chemical binding]; other site
634456001859	active site
634456001860	Predicted membrane protein [Function unknown]; Region: COG1238
634456001861	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
634456001862	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
634456001863	ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: TagH; COG1134
634456001864	ATP-binding cassette component of polysaccharide transport system; Region: ABC_KpsT_Wzt; cd03220
634456001865	Walker A/P-loop; other site
634456001866	ATP binding site [chemical binding]; other site
634456001867	Q-loop/lid; other site
634456001868	ABC transporter signature motif; other site
634456001869	Walker B; other site
634456001870	D-loop; other site
634456001871	H-loop/switch region; other site
634456001872	ABC-type polysaccharide/polyol phosphate export systems, permease component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: TagG; COG1682
634456001873	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
634456001874	ribose-phosphate pyrophosphokinase; Provisional; Region: PRK01259
634456001875	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
634456001876	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
634456001877	active site
634456001878	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
634456001879	catalytic core [active]
634456001880	Protein of unknown function (DUF1269); Region: DUF1269; cl01978
634456001881	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
634456001882	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
634456001883	short chain dehydrogenase; Provisional; Region: PRK12744
634456001884	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
634456001885	NAD(P) binding site [chemical binding]; other site
634456001886	active site
634456001887	transcriptional regulator; Provisional; Region: PRK10632
634456001888	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
634456001889	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_3; cd08472
634456001890	putative effector binding pocket; other site
634456001891	putative dimerization interface [polypeptide binding]; other site
634456001892	NhaP-type Na+/H+ and K+/H+ antiporters [Inorganic ion transport and metabolism]; Region: NhaP; COG0025
634456001893	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; cl10482
634456001894	Outer membrane cobalamin receptor protein [Coenzyme metabolism]; Region: BtuB; COG4206
634456001895	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
634456001896	N-terminal plug; other site
634456001897	ligand-binding site [chemical binding]; other site
634456001898	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
634456001899	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
634456001900	intersubunit interface [polypeptide binding]; other site
634456001901	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cl00462
634456001902	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
634456001903	putative PBP binding regions; other site
634456001904	ABC-ATPase subunit  interface; other site
634456001905	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
634456001906	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
634456001907	Walker A/P-loop; other site
634456001908	ATP binding site [chemical binding]; other site
634456001909	Q-loop/lid; other site
634456001910	ABC transporter signature motif; other site
634456001911	Walker B; other site
634456001912	D-loop; other site
634456001913	H-loop/switch region; other site
634456001914	Glycosyl hydrolase family 20, domain 2; Region: Glyco_hydro_20b; pfam02838
634456001915	Beta-N-acetylhexosaminidases of glycosyl hydrolase family 20 (GH20) catalyze the removal of beta-1,4-linked N-acetyl-D-hexosamine residues from the non-reducing ends of N-acetyl-beta-D-hexosaminides including N-acetylglucosides and N-acetylgalactosides; Region: GH20_hexosaminidase; cl02948
634456001916	Glycosyl hydrolase family 20, catalytic domain; Region: Glyco_hydro_20; pfam00728
634456001917	active site
634456001918	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
634456001919	nucleotide binding site [chemical binding]; other site
634456001920	N-acetylmuramic acid-6-phosphate etherase; Reviewed; Region: murQ; PRK05441
634456001921	N-acetylmuramic acid 6-phosphate etherase. Members of this family contain the SIS (Sugar ISomerase) domain. The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. The bacterial cell wall sugar N-acetylmuramic acid...; Region: SIS_Etherase; cd05007
634456001922	putative active site [active]
634456001923	uncharacterized subgroup of the Na(+)/iodide (NIS) cotransporter subfamily; putative solute-binding domain; Region: SLC5sbd_NIS-like_u1; cd11493
634456001924	Na binding site [ion binding]; other site
634456001925	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
634456001926	long tail fiber, proximal subunit; Provisional; Region: 34; PHA02584
634456001927	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
634456001928	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
634456001929	Transposase DDE domain group 1; Region: DDE_Tnp_1_4; pfam13701
634456001930	Hint domain; Region: Hint_2; pfam13403
634456001931	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cl02459
634456001932	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
634456001933	helix_turn_helix, Lux Regulon; Region: HTH_LUXR; smart00421
634456001934	DNA binding residues [nucleotide binding]
634456001935	dimerization interface [polypeptide binding]; other site
634456001936	Hint domain; Region: Hint_2; pfam13403
634456001937	FAD binding domain of DNA photolyase; Region: FAD_binding_7; pfam03441
634456001938	DNA photolyase; Region: DNA_photolyase; pfam00875
634456001939	Conserved domain frequently associated with peptide methionine sulfoxide reductase [Posttranslational modification, protein turnover, chaperones]; Region: COG0229; cl15841
634456001940	SelR domain; Region: SelR; pfam01641
634456001941	Domain of unknown function (DUF4112); Region: DUF4112; pfam13430
634456001942	Domain of unknown function DUF20; Region: UPF0118; pfam01594
634456001943	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
634456001944	aspartate 4-decarboxylase; Region: asp_4_decarbox; TIGR03801
634456001945	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
634456001946	pyridoxal 5'-phosphate binding site [chemical binding]; other site
634456001947	homodimer interface [polypeptide binding]; other site
634456001948	catalytic residue [active]
634456001949	FOG: Transposase [DNA replication, recombination, and repair]; Region: COG5659
634456001950	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
634456001951	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
634456001952	Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; pfam13340
634456001953	Hint domain; Region: Hint_2; pfam13403
634456001954	DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism]; Region: Dps; COG0783
634456001955	DPS protein, ferritin-like diiron-binding domain; Region: DPS; cd01043
634456001956	dimerization interface [polypeptide binding]; other site
634456001957	DPS ferroxidase diiron center [ion binding]; other site
634456001958	ion pore; other site
634456001959	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Validated; Region: gpsA; PRK00094
634456001960	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
634456001961	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479
634456001962	Bacterioferritin-associated ferredoxin [Inorganic ion transport and metabolism]; Region: Bfd; COG2906
634456001963	Bacterial Transmembrane Pair family; Region: BTP; pfam05232
634456001964	Bacterial Transmembrane Pair family; Region: BTP; pfam05232
634456001965	Transcriptional regulator [Transcription]; Region: LysR; COG0583
634456001966	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
634456001967	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
634456001968	dimerization interface [polypeptide binding]; other site
634456001969	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cl15354
634456001970	methylamine dehydrogenase (amicyanin) heavy chain; Region: TTQ_MADH_Hv; TIGR02658
634456001971	Methylamine utilisation protein MauE; Region: MauE; pfam07291
634456001972	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
634456001973	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
634456001974	Methylamine dehydrogenase, L chain; Region: Me-amine-dh_L; cl03812
634456001975	Outer membrane protein family (DUF1597); Region: DUF1597; pfam07642
634456001976	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
634456001977	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
634456001978	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
634456001979	active site
634456001980	catalytic tetrad [active]
634456001981	Transcriptional regulator [Transcription]; Region: LysR; COG0583
634456001982	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
634456001983	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
634456001984	dimerization interface [polypeptide binding]; other site
634456001985	Escherichia coli lactaldehyde dehydrogenase AldA-like; Region: ALDH_LactADH-AldA; cd07088
634456001986	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
634456001987	NAD binding site [chemical binding]; other site
634456001988	catalytic residues [active]
634456001989	substrate binding site [chemical binding]; other site
634456001990	Cytochrome c; Region: Cytochrom_C; cl11414
634456001991	Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010
634456001992	Cytochrome C oxidase, cbb3-type, subunit III; Region: Cytochrome_CBB3; pfam13442
634456001993	Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738
634456001994	Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs [Energy production and conversion]; Region: CoxL; COG1529
634456001995	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Region: Ald_Xan_dh_C; smart01008
634456001996	Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738
634456001997	Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738
634456001998	Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs [Energy production and conversion]; Region: CoxS; COG2080
634456001999	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
634456002000	catalytic loop [active]
634456002001	iron binding site [ion binding]; other site
634456002002	[2Fe-2S] binding domain; Region: Fer2_2; pfam01799
634456002003	Protein of unknown function (DUF563); Region: DUF563; pfam04577
634456002004	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
634456002005	S-adenosylmethionine binding site [chemical binding]; other site
634456002006	Pertactin-like passenger domains (virulence factors) of autotransporter proteins of the type V secretion system. Autotransporters are proteins used by Gram-negative bacteria to transport proteins across their outer membranes. The C-terminal (beta) domain...; Region: PL_Passenger_AT; cl00185
634456002007	Hint domain; Region: Hint_2; pfam13403
634456002008	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
634456002009	putative substrate translocation pore; other site
634456002010	Major Facilitator Superfamily; Region: MFS_1; pfam07690
634456002011	Predicted restriction endonuclease [Defense mechanisms]; Region: COG3183
634456002012	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
634456002013	Predicted integral membrane protein [Function unknown]; Region: COG0762
634456002014	Protein of unknown function (DUF1275); Region: DUF1275; pfam06912
634456002015	Protein of unknown function (DUF805); Region: DUF805; pfam05656
634456002016	CHRD domain; Region: CHRD; pfam07452
634456002017	Predicted membrane protein [Function unknown]; Region: COG3650
634456002018	META domain; Region: META; pfam03724
634456002019	Hint domain; Region: Hint_2; pfam13403
634456002020	T5orf172 domain; Region: T5orf172; pfam10544
634456002021	Invasion associated locus B (IalB) protein; Region: IalB; cl02207
634456002022	TonB-dependent siderophore receptor; Region: TonB-siderophor; TIGR01783
634456002023	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
634456002024	N-terminal plug; other site
634456002025	ligand-binding site [chemical binding]; other site
634456002026	Cytochrome c; Region: Cytochrom_C; pfam00034
634456002027	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
634456002028	FAD dependent oxidoreductase; Region: DAO; pfam01266
634456002029	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
634456002030	NmrA-like family; Region: NmrA; pfam05368
634456002031	NAD(P) binding site [chemical binding]; other site
634456002032	active site
634456002033	Protein of unknown function (DUF1311); Region: DUF1311; cl01530
634456002034	Hint domain; Region: Hint_2; pfam13403
634456002035	Hint domain; Region: Hint_2; pfam13403
634456002036	Putative threonine efflux protein [Amino acid transport and metabolism]; Region: RhtB; COG1280
634456002037	Hint domain; Region: Hint_2; pfam13403
634456002038	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
634456002039	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
634456002040	non-specific DNA binding site [nucleotide binding]; other site
634456002041	salt bridge; other site
634456002042	sequence-specific DNA binding site [nucleotide binding]; other site
634456002043	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
634456002044	Catalytic site [active]
634456002045	Formate/glycerate dehydrogenases, D-specific 2-hydroxy acid dehydrogenases and related dehydrogenases; Region: FDH_GDH_like; cl17240
634456002046	Hint domain; Region: Hint_2; pfam13403
634456002047	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
634456002048	Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or C-terminal to the catalytic domain. These enzymes perform site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining...; Region: Ser_Recombinase; cl02788
634456002049	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
634456002050	DNA-binding interface [nucleotide binding]; DNA binding site
634456002051	Hint domain; Region: Hint_2; pfam13403
634456002052	B12 binding domain_like associated with radical SAM domain. This domain shows similarity with B12 (adenosylcobamide) binding domains found in several enzymes, such as glutamate mutase, methionine synthase and methylmalonyl-CoA mutase, but it lacks the...; Region: radical_SAM_B12_BD; cd02068
634456002053	Elongator protein 3, MiaB family, Radical SAM; Region: Elp3; smart00729
634456002054	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
634456002055	FeS/SAM binding site; other site
634456002056	Predicted acyltransferases [Lipid metabolism]; Region: COG1835
634456002057	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5410
634456002058	Terminase-like family; Region: Terminase_6; pfam03237
634456002059	Phage-related terminase [General function prediction only]; Region: COG5362; cl02216
634456002060	hypothetical protein; Validated; Region: PRK01415
634456002061	Member of the Rhodanese Homology Domain superfamily. This CD includes Escherichia coli YceA, Bacillus subtilis YbfQ, and similar uncharacterized proteins; Region: RHOD_YceA; cd01518
634456002062	active site residue [active]
634456002063	Protein of unknown function (DUF1073); Region: DUF1073; pfam06381
634456002064	phage-related protein, HI1409 family; Region: phge_rel_HI1409; TIGR01555
634456002065	Uncharacterized protein conserved in bacteria (DUF2213); Region: DUF2213; pfam09979
634456002066	Uncharacterized protein conserved in bacteria (DUF2184); Region: DUF2184; pfam09950
634456002067	Protein of unknown function (DUF4054); Region: DUF4054; pfam13262
634456002068	Protein of unknown function (DUF3383); Region: DUF3383; pfam11863
634456002069	Protein of unknown function (DUF3383); Region: DUF3383; pfam11863
634456002070	Transposase DDE domain group 1; Region: DDE_Tnp_1_4; pfam13701
634456002071	phage baseplate assembly protein V; Region: phage_P2_V; TIGR01644
634456002072	Protein of unknown function (DUF2612); Region: DUF2612; pfam11041
634456002073	NhaP-type Na+/H+ and K+/H+ antiporters [Inorganic ion transport and metabolism]; Region: NhaP; COG0025
634456002074	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
634456002075	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
634456002076	Phosphotransferase enzyme family; Region: APH; pfam01636
634456002077	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cl17270
634456002078	substrate binding site [chemical binding]; other site
634456002079	Nicotinamide mononucleotide transporter; Region: NMN_transporter; pfam04973
634456002080	Domain of unknown function (DUF3315); Region: DUF3315; cl02275
634456002081	formyltetrahydrofolate deformylase; Reviewed; Region: purU; PRK06027
634456002082	N-terminal ACT domain of formyltetrahydrofolate deformylase (F4HF-DF; formyltetrahydrofolate hydrolase); Region: ACT_F4HF-DF; cd04875
634456002083	Formyltetrahydrofolate deformylase (Formyl-FH4 hydrolase), C-terminal hydrolase domain; Region: FMT_core_Formyl-FH4-Hydrolase_C; cd08648
634456002084	putative active site [active]
634456002085	putative substrate binding site [chemical binding]; other site
634456002086	putative cosubstrate binding site; other site
634456002087	catalytic site [active]
634456002088	Uncharacterized conserved protein [Function unknown]; Region: COG3189
634456002089	Predicted transcriptional regulator [Transcription]; Region: COG1959
634456002090	Transcriptional regulator; Region: Rrf2; cl17282
634456002091	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
634456002092	malonic semialdehyde reductase; Provisional; Region: PRK10538
634456002093	NAD(P) binding site [chemical binding]; other site
634456002094	active site
634456002095	CrcB-like protein; Region: CRCB; cl09114
634456002096	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_19; cd07262
634456002097	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
634456002098	Ferritin-like superfamily of diiron-containing four-helix-bundle proteins; Region: Ferritin_like; cd00657
634456002099	dinuclear metal binding motif [ion binding]; other site
634456002100	Brown fat-inducible thioesterase (BFIT).  Brain acyl-CoA hydrolase (BACH).  These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis; Region: BFIT_BACH; cd03442
634456002101	Hint domain; Region: Hint_2; pfam13403
634456002102	Periplasmic protein TonB, links inner and outer membranes [Cell envelope biogenesis, outer membrane]; Region: TonB; COG0810
634456002103	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
634456002104	Predicted metalloendopeptidase [Posttranslational modification, protein turnover, chaperones]; Region: PepO; COG3590
634456002105	Peptidase family M13 includes neprilysin, endothelin-converting enzyme I; Region: M13; cd08662
634456002106	active site
634456002107	Zn binding site [ion binding]; other site
634456002108	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
634456002109	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
634456002110	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
634456002111	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
634456002112	Coenzyme A transferase; Region: CoA_trans; smart00882
634456002113	Transposase DDE domain group 1; Region: DDE_Tnp_1_4; pfam13701
634456002114	Transposase DDE domain group 1; Region: DDE_Tnp_1_4; pfam13701
634456002115	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
634456002116	Coenzyme A transferase; Region: CoA_trans; cl17247
634456002117	Putative glycerate kinase [Carbohydrate transport and metabolism]; Region: GckA; COG2379
634456002118	Domain of unknown function (DUF4147); Region: DUF4147; pfam13660
634456002119	MOFRL family; Region: MOFRL; pfam05161
634456002120	Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960
634456002121	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
634456002122	active site
634456002123	3-ketoacyl-(acyl-carrier-protein) reductase; Provisional; Region: PRK12745
634456002124	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
634456002125	NAD(P) binding site [chemical binding]; other site
634456002126	active site
634456002127	Protein of unknown function (DUF993); Region: DUF993; pfam06187
634456002128	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
634456002129	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cl12060
634456002130	DNA interaction; other site
634456002131	Metal-binding active site; metal-binding site
634456002132	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_beta; cd01714
634456002133	Electron transfer flavoprotein domain; Region: ETF; pfam01012
634456002134	Ligand binding site [chemical binding]; other site
634456002135	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
634456002136	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
634456002137	Transposase DDE domain group 1; Region: DDE_Tnp_1_4; pfam13701
634456002138	Electron transfer flavoprotein, alpha subunit [Energy production and conversion]; Region: FixB; COG2025
634456002139	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_alpha; cd01715
634456002140	Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766
634456002141	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
634456002142	Gluconobacter oxydans L-sorbosone dehydrogenase-like; Region: ALDH_SNDH; cd07118
634456002143	NAD(P) binding site [chemical binding]; other site
634456002144	catalytic residues [active]
634456002145	choline dehydrogenase; Validated; Region: PRK02106
634456002146	GMC oxidoreductase; Region: GMC_oxred_C; pfam05199
634456002147	Fucose permease [Carbohydrate transport and metabolism]; Region: FucP; COG0738
634456002148	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
634456002149	putative substrate translocation pore; other site
634456002150	Carbohydrate-selective porin, OprB family; Region: OprB; pfam04966
634456002151	Hint domain; Region: Hint_2; pfam13403
634456002152	Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; pfam13340
634456002153	Transposase DDE domain group 1; Region: DDE_Tnp_1_4; pfam13701
634456002154	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
634456002155	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
634456002156	polyphosphate kinase 2, PA0141 family; Region: PPK2_P_aer; TIGR03707
634456002157	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
634456002158	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
634456002159	Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit [Energy production and conversion]; Region: AcoA; COG1071
634456002160	Thiamine pyrophosphate (TPP) family, E1 of PDC_ADC_BCADC subfamily, TPP-binding module; composed of proteins similar to the E1 components of the human pyruvate dehydrogenase complex (PDC), the acetoin dehydrogenase complex (ADC) and the branched chain...; Region: TPP_E1_PDC_ADC_BCADC; cd02000
634456002161	tetramer interface [polypeptide binding]; other site
634456002162	TPP-binding site [chemical binding]; other site
634456002163	heterodimer interface [polypeptide binding]; other site
634456002164	phosphorylation loop region [posttranslational modification]
634456002165	Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit [Energy production and conversion]; Region: AcoB; COG0022
634456002166	Pyrimidine (PYR) binding domain of the beta subunits of the E1 components of human pyruvate dehydrogenase complex (E1- PDHc) and related proteins; Region: TPP_PYR_E1-PDHc-beta_like; cd07036
634456002167	alpha subunit interface [polypeptide binding]; other site
634456002168	TPP binding site [chemical binding]; other site
634456002169	heterodimer interface [polypeptide binding]; other site
634456002170	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
634456002171	acetoin dehydrogenase E2 subunit dihydrolipoyllysine-residue acetyltransferase; Provisional; Region: PRK14875
634456002172	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
634456002173	E3 interaction surface; other site
634456002174	lipoyl attachment site [posttranslational modification]; other site
634456002175	Novel bacterial esterase that cleaves esters on halogenated cyclic compounds; Region: Esterase_713_like; cl17303
634456002176	catalytic site [active]
634456002177	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
634456002178	Alpha-crystallin domain (ACD) of alpha-crystallin-type small(s) heat shock proteins (Hsps). sHsps are small stress induced proteins with monomeric masses between 12 -43 kDa, whose common feature is the Alpha-crystallin domain  (ACD). sHsps are generally...; Region: ACD_sHsps-like; cd06464
634456002179	putative dimer interface [polypeptide binding]; other site
634456002180	NADH dehydrogenase, FAD-containing subunit [Energy production and conversion]; Region: Ndh; COG1252
634456002181	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
634456002182	FOG: WD40 repeat [General function prediction only]; Region: COG2319
634456002183	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cl02567
634456002184	structural tetrad; other site
634456002185	Putative GTPases (G3E family) [General function prediction only]; Region: COG0523
634456002186	The function of this protein family is unkown. The amino acid sequence of YjiA protein in E. coli contains several conserved motifs that characterizes it as a P-loop GTPase. YijA gene is among the genes significantly induced in response to DNA-damage...; Region: CobW_like; cd03112
634456002187	P-loop, Walker A motif; other site
634456002188	Base recognition motif; other site
634456002189	Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; pfam07683
634456002190	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
634456002191	ClC chloride channel family. These protein sequences, closely related to the ClC Eric family, are putative halogen ion (Cl-, Br- and I-) transport proteins found in eubacteria. They belong to the ClC superfamily of chloride ion channels, which share a...; Region: EriC_like; cd01034
634456002192	putative ion selectivity filter; other site
634456002193	putative pore gating glutamate residue; other site
634456002194	putative H+/Cl- coupling transport residue; other site
634456002195	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
634456002196	cation diffusion facilitator family transporter; Region: CDF; TIGR01297
634456002197	Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism]; Region: CzcD; COG1230
634456002198	Uncharacterized FAD-dependent dehydrogenases [General function prediction only]; Region: COG2509
634456002199	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
634456002200	acyl-CoA esterase; Provisional; Region: PRK10673
634456002201	PGAP1-like protein; Region: PGAP1; pfam07819
634456002202	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
634456002203	Ligand Binding Site [chemical binding]; other site
634456002204	Predicted membrane protein [Function unknown]; Region: COG1297
634456002205	putative oligopeptide transporter, OPT family; Region: TIGR00733
634456002206	Domain of unknown function (DUF4104); Region: DUF4104; pfam13372
634456002207	Protein of unknown function (DUF3126); Region: DUF3126; pfam11324
634456002208	Protein of unknown function (DUF2939); Region: DUF2939; pfam11159
634456002209	molybdopterin biosynthesis protein MoeB; Provisional; Region: PRK05690
634456002210	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
634456002211	ATP binding site [chemical binding]; other site
634456002212	substrate interface [chemical binding]; other site
634456002213	Bacterial SH3 domain; Region: SH3_4; pfam06347
634456002214	Bacterial SH3 domain; Region: SH3_4; pfam06347
634456002215	pyruvate kinase; Provisional; Region: PRK06247
634456002216	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cl17342
634456002217	domain interfaces; other site
634456002218	active site
634456002219	Gluconolactonase [Carbohydrate transport and metabolism]; Region: COG3386
634456002220	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
634456002221	putative substrate translocation pore; other site
634456002222	Major Facilitator Superfamily; Region: MFS_1; pfam07690
634456002223	Predicted membrane GTPase involved in stress response [Signal transduction mechanisms]; Region: TypA; COG1217
634456002224	Tyrosine phosphorylated protein A (TypA)/BipA family belongs to ribosome-binding GTPases; Region: TypA_BipA; cd01891
634456002225	G1 box; other site
634456002226	putative GEF interaction site [polypeptide binding]; other site
634456002227	GTP/Mg2+ binding site [chemical binding]; other site
634456002228	Switch I region; other site
634456002229	G2 box; other site
634456002230	G3 box; other site
634456002231	Switch II region; other site
634456002232	G4 box; other site
634456002233	G5 box; other site
634456002234	BipA_TypA_II: domain II of BipA (also called TypA) having homology to domain II of the elongation factors (EFs) EF-G and EF-Tu.  BipA is a highly conserved protein with global regulatory properties in Escherichia coli. BipA is phosphorylated on a...; Region: BipA_TypA_II; cd03691
634456002235	BipA_TypA_C: a C-terminal portion of BipA or TypA having homology to the C terminal domains of the elongation factors EF-G and EF-2. A member of the ribosome binding GTPase superfamily, BipA is widely distributed in bacteria and plants.  BipA is a highly...; Region: BipA_TypA_C; cd03710
634456002236	D-amino acid dehydrogenase small subunit; Validated; Region: PRK00711
634456002237	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
634456002238	hydroxyglutarate oxidase; Provisional; Region: PRK11728
634456002239	Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones]; Region: TrxB; COG0492
634456002240	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
634456002241	isocitrate dehydrogenase; Validated; Region: PRK08299
634456002242	hypothetical protein; Provisional; Region: PRK08912
634456002243	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
634456002244	pyridoxal 5'-phosphate binding site [chemical binding]; other site
634456002245	homodimer interface [polypeptide binding]; other site
634456002246	catalytic residue [active]
634456002247	Nitrogen regulatory protein P-II; Region: P-II; pfam00543
634456002248	Nitrogen regulatory protein P-II; Region: P-II; smart00938
634456002249	glutamine synthetase; Provisional; Region: glnA; PRK09469
634456002250	Glutamine synthetase, beta-Grasp domain; Region: Gln-synt_N; pfam03951
634456002251	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
634456002252	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
634456002253	membrane-bound PQQ-dependent dehydrogenase, glucose/quinate/shikimate family; Region: PQQ_membr_DH; TIGR03074
634456002254	Membrane-bound PQQ-dependent glucose dehydrogenase; Region: PQQ_mGDH; cd10280
634456002255	Trp docking motif [polypeptide binding]; other site
634456002256	putative active site [active]
634456002257	Predicted transcriptional regulator [Transcription]; Region: COG2932
634456002258	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
634456002259	Catalytic site [active]
634456002260	GTP-binding protein LepA; Provisional; Region: PRK05433
634456002261	LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890
634456002262	G1 box; other site
634456002263	putative GEF interaction site [polypeptide binding]; other site
634456002264	GTP/Mg2+ binding site [chemical binding]; other site
634456002265	Switch I region; other site
634456002266	G2 box; other site
634456002267	G3 box; other site
634456002268	Switch II region; other site
634456002269	G4 box; other site
634456002270	G5 box; other site
634456002271	lepA_II: This subfamily represents the domain II of LepA, a GTP-binding protein localized in the cytoplasmic membrane. The N-terminal domain of LepA shares regions of homology to translation factors. In terms of interaction with the ribosome, EF-G, EF-Tu...; Region: lepA_II; cd03699
634456002272	lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane.   LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709
634456002273	GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421
634456002274	homoserine O-acetyltransferase; Provisional; Region: metX; PRK00175
634456002275	homoserine O-acetyltransferase; Region: homoserO_Ac_trn; TIGR01392
634456002276	Methyltransferase domain; Region: Methyltransf_23; pfam13489
634456002277	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
634456002278	S-adenosylmethionine binding site [chemical binding]; other site
634456002279	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
634456002280	DEAD-like helicases superfamily; Region: DEXDc; smart00487
634456002281	ATP binding site [chemical binding]; other site
634456002282	Mg++ binding site [ion binding]; other site
634456002283	motif III; other site
634456002284	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
634456002285	nucleotide binding region [chemical binding]; other site
634456002286	ATP-binding site [chemical binding]; other site
634456002287	Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily; Region: EEP; cl00490
634456002288	putative catalytic site [active]
634456002289	putative metal binding site [ion binding]; other site
634456002290	putative phosphate binding site [ion binding]; other site
634456002291	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeB; cd00884
634456002292	active site clefts [active]
634456002293	zinc binding site [ion binding]; other site
634456002294	dimer interface [polypeptide binding]; other site
634456002295	LabA_like proteins; Region: LabA; cd10911
634456002296	Uncharacterized conserved protein [Function unknown]; Region: COG1432
634456002297	putative metal binding site [ion binding]; other site
634456002298	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after...; Region: HPPK; cd00483
634456002299	catalytic center binding site [active]
634456002300	ATP binding site [chemical binding]; other site
634456002301	DNA-directed RNA polymerase subunit omega; Reviewed; Region: rpoZ; PRK00392
634456002302	Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription]; Region: SpoT; COG0317
634456002303	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
634456002304	Zn2+ binding site [ion binding]; other site
634456002305	Mg2+ binding site [ion binding]; other site
634456002306	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
634456002307	synthetase active site [active]
634456002308	NTP binding site [chemical binding]; other site
634456002309	metal binding site [ion binding]; metal-binding site
634456002310	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
634456002311	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
634456002312	4'-phosphopantetheinyl transferase; Provisional; Region: acpS; PRK00070
634456002313	signal peptidase I, bacterial type; Region: sigpep_I_bact; TIGR02227
634456002314	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
634456002315	Catalytic site [active]
634456002316	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
634456002317	ribonuclease III; Reviewed; Region: rnc; PRK00102
634456002318	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
634456002319	dimerization interface [polypeptide binding]; other site
634456002320	active site
634456002321	metal binding site [ion binding]; metal-binding site
634456002322	Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048
634456002323	GTPase Era; Reviewed; Region: era; PRK00089
634456002324	E. coli Ras-like protein (Era) is a multifunctional GTPase; Region: Era; cd04163
634456002325	G1 box; other site
634456002326	GTP/Mg2+ binding site [chemical binding]; other site
634456002327	Switch I region; other site
634456002328	G2 box; other site
634456002329	Switch II region; other site
634456002330	G3 box; other site
634456002331	G4 box; other site
634456002332	G5 box; other site
634456002333	KH domain; Region: KH_2; pfam07650
634456002334	UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and...; Region: AAK_UMPK-PyrH-Ec; cd04254
634456002335	putative nucleotide binding site [chemical binding]; other site
634456002336	uridine monophosphate binding site [chemical binding]; other site
634456002337	homohexameric interface [polypeptide binding]; other site
634456002338	ribosome recycling factor; Reviewed; Region: frr; PRK00083
634456002339	Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation.  Thus ribosomes are "recycled" and ready for another...; Region: RRF; cd00520
634456002340	hinge region; other site
634456002341	Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS); homodimers which catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl...; Region: CIS_IPPS; cl00230
634456002342	Putative undecaprenyl diphosphate synthase; Region: Prenyltransf; pfam01255
634456002343	catalytic residue [active]
634456002344	putative FPP diphosphate  binding site; other site
634456002345	putative FPP binding hydrophobic cleft; other site
634456002346	dimer interface [polypeptide binding]; other site
634456002347	putative IPP diphosphate binding site; other site
634456002348	Cytidylyltransferase family; Region: CTP_transf_1; pfam01148
634456002349	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
634456002350	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Provisional; Region: PRK05447
634456002351	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Region: DXP_reductoisom; pfam02670
634456002352	1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal; Region: DXP_redisom_C; pfam08436
634456002353	DXP reductoisomerase C-terminal domain; Region: DXPR_C; pfam13288
634456002354	Predicted membrane-associated Zn-dependent proteases 1 [Cell envelope biogenesis, outer membrane]; Region: COG0750
634456002355	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
634456002356	active site
634456002357	PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated; Region: PDZ; cl00117
634456002358	Site-2 protease (S2P) class of zinc metalloproteases (MEROPS family M50) cleaves transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of this family use proteolytic...; Region: S2P-M50; cl10020
634456002359	putative substrate binding region [chemical binding]; other site
634456002360	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
634456002361	outer membrane protein assembly complex, YaeT protein; Region: OM_YaeT; TIGR03303
634456002362	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
634456002363	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
634456002364	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
634456002365	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
634456002366	Surface antigen; Region: Bac_surface_Ag; pfam01103
634456002367	Outer membrane protein (OmpH-like); Region: OmpH; smart00935
634456002368	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Region: lipid_A_lpxD; TIGR01853
634456002369	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD; Region: LpxD; pfam04613
634456002370	UDP-3-O-acyl-glucosamine N-acyltransferase (LpxD): The enzyme catalyzes the transfer of 3-hydroxymyristic acid or 3-hydroxy-arachidic acid, depending on the organism, from the acyl carrier protein (ACP) to UDP-3-O-acyl-glucosamine to produce UDP-2; Region: LbH_LpxD; cd03352
634456002371	trimer interface [polypeptide binding]; other site
634456002372	active site
634456002373	UDP-GlcNAc binding site [chemical binding]; other site
634456002374	lipid binding site [chemical binding]; lipid-binding site
634456002375	FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid...; Region: FabZ; cd01288
634456002376	UDP-N-acetylglucosamine acyltransferase; Provisional; Region: PRK05289
634456002377	UDP-N-acetylglucosamine O-acyltransferase (UDP-GlcNAc acyltransferase): Proteins in this family catalyze the transfer of (R)-3-hydroxymyristic acid from its acyl carrier protein thioester to UDP-GlcNAc. It is the first enzyme in the lipid A biosynthetic...; Region: LbH_UDP-GlcNAc_AT; cd03351
634456002378	active site
634456002379	Protein of unknown function (DUF1009); Region: DUF1009; pfam06230
634456002380	Glyoxalase I catalyzes the isomerization of the hemithioacetal, formed by a 2-oxoaldehyde and glutathione, to S-D-lactoylglutathione; Region: Glyoxalase_I; cd07233
634456002381	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
634456002382	dimer interface [polypeptide binding]; other site
634456002383	active site
634456002384	metal binding site [ion binding]; metal-binding site
634456002385	glutathione binding site [chemical binding]; other site
634456002386	50S ribosomal protein L34; Reviewed; Region: rpmH; PRK00399
634456002387	Ribonuclease P; Region: Ribonuclease_P; pfam00825
634456002388	membrane protein insertase; Provisional; Region: PRK01318
634456002389	membrane protein insertase, YidC/Oxa1 family, C-terminal domain; Region: yidC_oxa1_cterm; TIGR03592
634456002390	YihA (EngB) GTPase family; Region: YihA_EngB; cd01876
634456002391	G1 box; other site
634456002392	GTP/Mg2+ binding site [chemical binding]; other site
634456002393	Switch I region; other site
634456002394	G2 box; other site
634456002395	G3 box; other site
634456002396	Switch II region; other site
634456002397	G4 box; other site
634456002398	G5 box; other site
634456002399	AAK_NAGK-C: N-Acetyl-L-glutamate kinase - cyclic (NAGK-C) catalyzes the phosphorylation of the gamma-COOH group of N-acetyl-L-glutamate (NAG) by ATP in the second step of arginine biosynthesis found in some bacteria and photosynthetic organisms using the...; Region: AAK_NAGK-C; cd04250
634456002400	homohexameric interface [polypeptide binding]; other site
634456002401	feedback inhibition sensing region; other site
634456002402	nucleotide binding site [chemical binding]; other site
634456002403	N-acetyl-L-glutamate binding site [chemical binding]; other site
634456002404	2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase; Provisional; Region: dapD; PRK11830
634456002405	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate (THDP) N-succinyltransferase (also called THP succinyltransferase): THDP N-succinyltransferase catalyzes the conversion of tetrahydrodipicolinate and succinyl-CoA to N-succinyltetrahydrodipicolinate and CoA; Region: LbH_THP_succinylT; cd03350
634456002406	trimer interface [polypeptide binding]; other site
634456002407	active site
634456002408	substrate binding site [chemical binding]; other site
634456002409	CoA binding site [chemical binding]; other site
634456002410	succinyl-diaminopimelate desuccinylase; Reviewed; Region: PRK13009
634456002411	M20 Peptidase proteobacterial DapE encoded N-succinyl-L,L-diaminopimelic acid desuccinylase; Region: M20_DapE_proteobac; cd03891
634456002412	metal binding site [ion binding]; metal-binding site
634456002413	dimer interface [polypeptide binding]; other site
634456002414	tRNA pseudouridine synthase A; Validated; Region: truA; PRK00021
634456002415	Eukaryotic and bacterial pseudouridine synthases similar to E.  coli TruA; Region: PseudoU_synth_EcTruA; cd02570
634456002416	dimerization interface 3.5A [polypeptide binding]; other site
634456002417	active site
634456002418	methionyl-tRNA formyltransferase; Reviewed; Region: fmt; PRK00005
634456002419	Methionyl-tRNA formyltransferase, N-terminal hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N; cd08646
634456002420	putative active site [active]
634456002421	substrate binding site [chemical binding]; other site
634456002422	putative cosubstrate binding site; other site
634456002423	catalytic site [active]
634456002424	C-terminal domain of Formyltransferase and other enzymes; Region: Met_tRNA_FMT_C; cd08704
634456002425	substrate binding site [chemical binding]; other site
634456002426	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
634456002427	active site
634456002428	catalytic residues [active]
634456002429	metal binding site [ion binding]; metal-binding site
634456002430	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
634456002431	Alpha-crystallin domain (ACD) found in Escherichia coli inclusion body-associated proteins IbpA and IbpB, and similar proteins.  IbpA and IbpB are 16 kDa small heat shock proteins (sHsps). sHsps are molecular chaperones that suppress protein aggregation...; Region: ACD_IbpA-B_like; cd06470
634456002432	putative dimer interface [polypeptide binding]; other site
634456002433	Protein of unknown function (DUF1150); Region: DUF1150; cl11577
634456002434	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
634456002435	30S subunit binding site; other site
634456002436	Uncharacterized Fe-S protein [General function prediction only]; Region: COG3217
634456002437	MOSC N-terminal beta barrel domain; Region: MOSC_N; pfam03476
634456002438	MOSC domain; Region: MOSC; pfam03473
634456002439	ABC-type (unclassified) transport system, ATPase component [General function prediction only]; Region: YhbG; COG1137
634456002440	ATP-binding cassette component of YhbG transport system; Region: ABC_YhbG; cd03218
634456002441	Walker A/P-loop; other site
634456002442	ATP binding site [chemical binding]; other site
634456002443	Q-loop/lid; other site
634456002444	ABC transporter signature motif; other site
634456002445	Walker B; other site
634456002446	D-loop; other site
634456002447	H-loop/switch region; other site
634456002448	OstA-like protein; Region: OstA; cl00844
634456002449	OstA-like protein; Region: OstA; cl00844
634456002450	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5375
634456002451	KpsF/GutQ family protein; Region: kpsF; TIGR00393
634456002452	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
634456002453	putative active site [active]
634456002454	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with KpsF/GutQ domains in the API [A5P (D-arabinose 5-phosphate) isomerase] protein.  These APIs catalyze the conversion of the pentose pathway...; Region: CBS_pair_KpsF_GutQ_assoc; cd04604
634456002455	Ribonuclease D [Translation, ribosomal structure and biogenesis]; Region: Rnd; COG0349
634456002456	DEDDy 3'-5' exonuclease domain of Ribonuclease D and similar proteins; Region: RNaseD_exo; cd06142
634456002457	catalytic site [active]
634456002458	putative active site [active]
634456002459	putative substrate binding site [chemical binding]; other site
634456002460	rRNA methylases [Translation, ribosomal structure and biogenesis]; Region: SpoU; COG0566
634456002461	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; smart00967
634456002462	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
634456002463	Permease for cytosine/purines, uracil, thiamine, allantoin; Region: Transp_cyt_pur; pfam02133
634456002464	Solute carrier families 5 and 6-like; solute binding domain; Region: SLC5-6-like_sbd; cl00456
634456002465	short chain dehydrogenase; Provisional; Region: PRK07024
634456002466	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
634456002467	NAD(P) binding site [chemical binding]; other site
634456002468	active site
634456002469	Guanylate kinase [Nucleotide transport and metabolism]; Region: Gmk; COG0194
634456002470	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
634456002471	catalytic site [active]
634456002472	G-X2-G-X-G-K; other site
634456002473	ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaE; COG2870
634456002474	RfaE encodes a bifunctional ADP-heptose synthase involved in the biosynthesis of the lipopolysaccharide (LPS) core precursor ADP-L-glycero-D-manno-heptose. LPS plays an important role in maintaining the structural integrity of the bacterial outer...; Region: RfaE_like; cd01172
634456002475	putative ribose interaction site [chemical binding]; other site
634456002476	putative ADP binding site [chemical binding]; other site
634456002477	rfaE bifunctional protein, domain II; Region: rfaE_dom_II; TIGR02199
634456002478	active site
634456002479	nucleotide binding site [chemical binding]; other site
634456002480	HIGH motif; other site
634456002481	KMSKS motif; other site
634456002482	AGE domain; N-acyl-D-glucosamine 2-epimerase domain; Responsible for intermediate epimerization during biosynthesis of N-acetylneuraminic acid. Catalytic mechanism is believed to be via nucleotide elimination and readdition and is ATP modulated. AGE is...; Region: AGE; cl00183
634456002483	dimerization interface [polypeptide binding]; other site
634456002484	putative active cleft [active]
634456002485	replicative DNA helicase; Provisional; Region: PRK09165
634456002486	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
634456002487	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
634456002488	Walker A motif; other site
634456002489	ATP binding site [chemical binding]; other site
634456002490	Walker B motif; other site
634456002491	DNA binding loops [nucleotide binding]
634456002492	Nuclease-related domain; Region: NERD; pfam08378
634456002493	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: COG3264
634456002494	Mechanosensitive ion channel; Region: MS_channel; pfam00924
634456002495	outer membrane lipoprotein LolB; Provisional; Region: lolB; PRK00022
634456002496	ABC-type transport system involved in resistance to organic solvents, ATPase component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2A; COG1127
634456002497	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
634456002498	Walker A/P-loop; other site
634456002499	ATP binding site [chemical binding]; other site
634456002500	Q-loop/lid; other site
634456002501	ABC transporter signature motif; other site
634456002502	Walker B; other site
634456002503	D-loop; other site
634456002504	H-loop/switch region; other site
634456002505	ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2B; COG0767
634456002506	Permease; Region: Permease; pfam02405
634456002507	DNA repair protein RadA; Provisional; Region: PRK11823
634456002508	Sms (bacterial radA) DNA repair protein. This protein is not related to archael radA any more than is to other RecA-like NTPases. Sms has a role in recombination and recombinational repair and is responsible for the stabilization or processing of...; Region: Sms; cd01121
634456002509	Walker A motif/ATP binding site; other site
634456002510	ATP binding site [chemical binding]; other site
634456002511	Walker B motif; other site
634456002512	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
634456002513	Gamma-aminobutyrate permease and related permeases [Amino acid transport and metabolism]; Region: AnsP; COG1113
634456002514	Protein of unknown function (DUF1275); Region: DUF1275; pfam06912
634456002515	bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase; Reviewed; Region: PRK11905
634456002516	Proline dehydrogenase; Region: Pro_dh; pfam01619
634456002517	NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961
634456002518	NAD(P) binding site [chemical binding]; other site
634456002519	catalytic residues [active]
634456002520	NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961
634456002521	Transcriptional regulators [Transcription]; Region: GntR; COG1802
634456002522	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
634456002523	DNA-binding site [nucleotide binding]; DNA binding site
634456002524	FCD domain; Region: FCD; pfam07729
634456002525	Protein of unknown function (DUF2501); Region: DUF2501; cl08197
634456002526	acetyl-CoA synthetase; Provisional; Region: PRK00174
634456002527	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
634456002528	acyl-activating enzyme (AAE) consensus motif; other site
634456002529	AMP binding site [chemical binding]; other site
634456002530	active site
634456002531	CoA binding site [chemical binding]; other site
634456002532	Protein of unknown function (DUF1653); Region: DUF1653; pfam07866
634456002533	FtsJ-like methyltransferase; Region: FtsJ; cl17430
634456002534	Protein of unknown function (DUF423); Region: DUF423; pfam04241
634456002535	Cobalamin adenosyltransferase; Region: Cob_adeno_trans; pfam01923
634456002536	hypothetical protein; Validated; Region: PRK09039
634456002537	FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277
634456002538	FAD binding domain; Region: FAD_binding_4; pfam01565
634456002539	Putative translation factor (SUA5) [Translation, ribosomal structure and biogenesis]; Region: SUA5; COG0009
634456002540	Putative GTP-binding controlling metal-binding; Region: SUA5; pfam03481
634456002541	CysQ, a 3'-Phosphoadenosine-5'-phosphosulfate (PAPS) 3'-phosphatase, is a bacterial member of the inositol monophosphatase family. It has been proposed that CysQ helps control intracellular levels of PAPS, which is an intermediate in...; Region: CysQ; cd01638
634456002542	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
634456002543	active site
634456002544	multifunctional aminopeptidase A; Provisional; Region: PRK00913
634456002545	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
634456002546	interface (dimer of trimers) [polypeptide binding]; other site
634456002547	Substrate-binding/catalytic site; other site
634456002548	Zn-binding sites [ion binding]; other site
634456002549	DNA polymerase III subunit chi; Validated; Region: PRK05728
634456002550	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
634456002551	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
634456002552	active site
634456002553	catalytic tetrad [active]
634456002554	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain [Posttranslational modification, protein turnover, chaperones]; Region: DegQ; COG0265
634456002555	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
634456002556	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
634456002557	protein binding site [polypeptide binding]; other site
634456002558	ATP-dependent helicase HrpB; Region: DEAH_box_HrpB; TIGR01970
634456002559	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
634456002560	ATP binding site [chemical binding]; other site
634456002561	putative Mg++ binding site [ion binding]; other site
634456002562	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
634456002563	nucleotide binding region [chemical binding]; other site
634456002564	ATP-dependent helicase C-terminal; Region: HrpB_C; pfam08482
634456002565	Heat shock protein 33 (Hsp33):  Cytosolic protein that acts as a molecular chaperone under oxidative conditions.  In normal (reducing) cytosolic conditions, four conserved Cys residues are coordinated by a Zn ion. Under oxidative stress (such as heat...; Region: Hsp33; cd00498
634456002566	dimerization interface [polypeptide binding]; other site
634456002567	domain crossover interface; other site
634456002568	redox-dependent activation switch; other site
634456002569	ornithine carbamoyltransferase; Provisional; Region: PRK00779
634456002570	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
634456002571	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
634456002572	acetylornithine transaminase protein; Provisional; Region: argD; PRK01278
634456002573	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
634456002574	inhibitor-cofactor binding pocket; inhibition site
634456002575	pyridoxal 5'-phosphate binding site [chemical binding]; other site
634456002576	catalytic residue [active]
634456002577	RecX family; Region: RecX; pfam02631
634456002578	CHAP domain; Region: CHAP; cl17642
634456002579	twin arginine translocase protein A; Provisional; Region: tatA; PRK00720
634456002580	methylthioribulose-1-phosphate dehydratase; Provisional; Region: PRK09220
634456002581	intersubunit interface [polypeptide binding]; other site
634456002582	active site
634456002583	Zn2+ binding site [ion binding]; other site
634456002584	Uncharacterized conserved protein, contains double-stranded beta-helix domain [Function unknown]; Region: COG1791
634456002585	Cupin domain; Region: Cupin_2; cl17218
634456002586	2,3-diketo-5-methylthio-1-phosphopentane phosphatase; Region: enolase-ppase; TIGR01691
634456002587	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cl17915
634456002588	motif II; other site
634456002589	bifunctional riboflavin kinase/FMN adenylyltransferase; Reviewed; Region: PRK05627
634456002590	FAD synthetase, N-terminal domain of the bifunctional enzyme; Region: FAD_synthetase_N; cd02064
634456002591	active site
634456002592	Riboflavin kinase; Region: Flavokinase; smart00904
634456002593	isoleucyl-tRNA synthetase; Reviewed; Region: ileS; PRK05743
634456002594	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
634456002595	active site
634456002596	HIGH motif; other site
634456002597	nucleotide binding site [chemical binding]; other site
634456002598	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
634456002599	active site
634456002600	KMSKS motif; other site
634456002601	Anticodon-binding domain of bacterial and eukaryotic mitochondrial isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_BEm; cd07960
634456002602	tRNA binding surface [nucleotide binding]; other site
634456002603	anticodon binding site; other site
634456002604	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
634456002605	lipoprotein signal peptidase; Provisional; Region: PRK14770
634456002606	Protein of unknown function (DUF3035); Region: DUF3035; pfam11233
634456002607	DNA mismatch repair protein; Reviewed; Region: mutL; PRK00095
634456002608	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
634456002609	ATP binding site [chemical binding]; other site
634456002610	Mg2+ binding site [ion binding]; other site
634456002611	G-X-G motif; other site
634456002612	MutL_Trans: transducer domain, having a ribosomal S5 domain 2-like fold, conserved in the C-terminal domain of DNA mismatch repair (MutL/MLH1/PMS2) family. This transducer domain is homologous to the second domain of the DNA gyrase B subunit, which is...; Region: MutL_Trans; cd00782
634456002613	ATP binding site [chemical binding]; other site
634456002614	MutL C terminal dimerisation domain; Region: MutL_C; pfam08676
634456002615	NADH:ubiquinone oxidoreductase subunit M; Reviewed; Region: PRK05846
634456002616	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
634456002617	Threonine/homoserine efflux transporter [Amino acid transport and metabolism]; Region: rhtA; COG5006
634456002618	EamA-like transporter family; Region: EamA; pfam00892
634456002619	DNA topoisomerase IV subunit B; Reviewed; Region: PRK05559
634456002620	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
634456002621	Mg2+ binding site [ion binding]; other site
634456002622	G-X-G motif; other site
634456002623	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
634456002624	anchoring element; other site
634456002625	dimer interface [polypeptide binding]; other site
634456002626	ATP binding site [chemical binding]; other site
634456002627	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
634456002628	active site
634456002629	putative metal-binding site [ion binding]; other site
634456002630	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
634456002631	Rrf2 family protein; Region: rrf2_super; TIGR00738
634456002632	Transcriptional regulator; Region: Rrf2; pfam02082
634456002633	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
634456002634	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
634456002635	dimer interface [polypeptide binding]; other site
634456002636	pyridoxal 5'-phosphate binding site [chemical binding]; other site
634456002637	catalytic residue [active]
634456002638	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; cl17254
634456002639	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
634456002640	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
634456002641	ligand binding site [chemical binding]; other site
634456002642	Protein of unknown function (DUF1491); Region: DUF1491; pfam07372
634456002643	C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526
634456002644	C-terminal peptidase (prc); Region: prc; TIGR00225
634456002645	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
634456002646	protein binding site [polypeptide binding]; other site
634456002647	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
634456002648	Catalytic dyad [active]
634456002649	Exoribonuclease R [Transcription]; Region: VacB; COG0557
634456002650	RNB domain; Region: RNB; pfam00773
634456002651	DNA topoisomerase I subunit omega; Validated; Region: PRK07561
634456002652	TOPRIM_TopoIA_TopoI: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to Escherichia coli DNA topoisomerase I.   Type IA DNA topoisomerases remove (relax) negative supercoils in the...; Region: TOPRIM_TopoIA_TopoI; cd03363
634456002653	active site
634456002654	interdomain interaction site; other site
634456002655	putative metal-binding site [ion binding]; other site
634456002656	nucleotide binding site [chemical binding]; other site
634456002657	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
634456002658	domain I; other site
634456002659	DNA binding groove [nucleotide binding]
634456002660	phosphate binding site [ion binding]; other site
634456002661	domain II; other site
634456002662	domain III; other site
634456002663	nucleotide binding site [chemical binding]; other site
634456002664	catalytic site [active]
634456002665	domain IV; other site
634456002666	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
634456002667	Topoisomerase C-terminal repeat; Region: Toprim_C_rpt; pfam13368
634456002668	Topoisomerase C-terminal repeat; Region: Toprim_C_rpt; pfam13368
634456002669	Topoisomerase C-terminal repeat; Region: Toprim_C_rpt; pfam13368
634456002670	Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake [DNA replication, recombination, and repair / Intracellular trafficking and secretion]; Region: Smf; COG0758
634456002671	DNA protecting protein DprA; Region: dprA; TIGR00732
634456002672	DDE superfamily endonuclease; Region: DDE_5; pfam13546
634456002673	Transposase DDE domain group 1; Region: DDE_Tnp_1_4; pfam13701
634456002674	FOG: Transposase [DNA replication, recombination, and repair]; Region: COG5659
634456002675	DNA recombination-mediator protein A; Region: DNA_processg_A; pfam02481
634456002676	DNA protecting protein DprA; Region: dprA; TIGR00732
634456002677	putative glycerol-3-phosphate acyltransferase PlsY; Provisional; Region: PRK00220
634456002678	dihydroorotase; Validated; Region: pyrC; PRK09357
634456002679	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
634456002680	Dihydroorotase (DHOase), subgroup IIa; DHOases catalyze the reversible interconversion of carbamoyl aspartate to dihydroorotate, a key reaction in pyrimidine biosynthesis. This subgroup also contains proteins that lack the active site, like unc-33, a C; Region: DHOase_IIa; cd01317
634456002681	active site
634456002682	aspartate carbamoyltransferase catalytic subunit; Provisional; Region: pyrB; PRK00856
634456002683	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
634456002684	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
634456002685	glutamyl-tRNA synthetase; Reviewed; Region: gltX; PRK01406
634456002686	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
634456002687	active site
634456002688	HIGH motif; other site
634456002689	nucleotide binding site [chemical binding]; other site
634456002690	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
634456002691	active site
634456002692	KMSKS motif; other site
634456002693	Domain of unknown function (DUF4131); Region: DUF4131; pfam13567
634456002694	Predicted membrane metal-binding protein [General function prediction only]; Region: ComEC; COG0658
634456002695	Competence protein; Region: Competence; pfam03772
634456002696	Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit [Function unknown]; Region: COG0599
634456002697	Predicted ATPase [General function prediction only]; Region: COG1485
634456002698	2-oxoglutarate dehydrogenase E1 component; Reviewed; Region: sucA; PRK09404
634456002699	Thiamine pyrophosphate (TPP) family, E1 of OGDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the 2-oxoglutarate dehydrogenase multienzyme complex (OGDC). OGDC catalyzes the oxidative decarboxylation of...; Region: TPP_E1_OGDC_like; cd02016
634456002700	TPP-binding site [chemical binding]; other site
634456002701	Transketolase, pyrimidine binding domain; Region: Transket_pyr; pfam02779
634456002702	dihydrolipoamide succinyltransferase; Validated; Region: PRK05704
634456002703	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
634456002704	E3 interaction surface; other site
634456002705	lipoyl attachment site [posttranslational modification]; other site
634456002706	e3 binding domain; Region: E3_binding; pfam02817
634456002707	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
634456002708	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
634456002709	E3 interaction surface; other site
634456002710	lipoyl attachment site [posttranslational modification]; other site
634456002711	dihydrolipoamide dehydrogenase; Validated; Region: PRK06327
634456002712	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
634456002713	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
634456002714	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
634456002715	Domain of unknown function (DUF3597); Region: DUF3597; pfam12200
634456002716	S-adenosyl-L-homocysteine hydrolase; Provisional; Region: PRK05476
634456002717	S-Adenosylhomocysteine Hydrolase, NAD-binding and catalytic domains; Region: SAHH; cd00401
634456002718	homotetramer interface [polypeptide binding]; other site
634456002719	ligand binding site [chemical binding]; other site
634456002720	catalytic site [active]
634456002721	NAD binding site [chemical binding]; other site
634456002722	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
634456002723	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
634456002724	putative acyl-acceptor binding pocket; other site
634456002725	Uncharacterized protein conserved in bacteria (DUF2125); Region: DUF2125; pfam09898
634456002726	hydroxyacylglutathione hydrolase; Region: GSH_gloB; TIGR03413
634456002727	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
634456002728	NADH dehydrogenase subunit D; Validated; Region: PRK06075; cl17338
634456002729	Ni,Fe-hydrogenase III large subunit [Energy production and conversion]; Region: HycE; COG3261
634456002730	NADH ubiquinone oxidoreductase, 20 Kd subunit; Region: Oxidored_q6; cl17194
634456002731	CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; pfam01066
634456002732	Phosphatidylserine synthase [Lipid metabolism]; Region: PssA; COG1183
634456002733	phosphatidylserine decarboxylase; Provisional; Region: PRK05305
634456002734	alanyl-tRNA synthetase; Reviewed; Region: alaS; PRK00252
634456002735	Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: AlaRS_core; cd00673
634456002736	motif 1; other site
634456002737	active site
634456002738	motif 2; other site
634456002739	motif 3; other site
634456002740	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
634456002741	TraB family; Region: TraB; cl12050
634456002742	Predicted membrane protein [Function unknown]; Region: COG2246
634456002743	GtrA-like protein; Region: GtrA; pfam04138
634456002744	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; cl17254
634456002745	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
634456002746	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
634456002747	ligand binding site [chemical binding]; other site
634456002748	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
634456002749	bifunctional shikimate kinase/3-dehydroquinate synthase; Provisional; Region: PRK14021
634456002750	ADP binding site [chemical binding]; other site
634456002751	magnesium binding site [ion binding]; other site
634456002752	putative shikimate binding site; other site
634456002753	Dehydroquinate synthase (DHQS) catalyzes the conversion of DAHP to DHQ in shikimate pathway for aromatic compounds synthesis; Region: DHQS; cd08195
634456002754	active site
634456002755	dimer interface [polypeptide binding]; other site
634456002756	metal binding site [ion binding]; metal-binding site
634456002757	site-specific tyrosine recombinase XerD; Reviewed; Region: xerD; PRK00283
634456002758	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
634456002759	active site
634456002760	DNA binding site [nucleotide binding]
634456002761	Int/Topo IB signature motif; other site
634456002762	acetyl-CoA carboxylase carboxyltransferase subunit alpha; Validated; Region: PRK05724
634456002763	acetyl-CoA carboxylase carboxyltransferase alpha subunit; Provisional; Region: accA; CHL00198
634456002764	Competence-damaged protein. CinA is the first gene in the competence- inducible (cin) operon and is thought to be specifically required at some stage in the process of transformation. This domain is closely related to a domain, found in a variety of...; Region: cinA; cd00885
634456002765	Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA [General function prediction only]; Region: CinA; COG1058
634456002766	putative MPT binding site; other site
634456002767	lysyl-tRNA synthetase; Reviewed; Region: lysK; PRK00750
634456002768	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
634456002769	active site
634456002770	nucleotide binding site [chemical binding]; other site
634456002771	HIGH motif; other site
634456002772	KMSKS motif; other site
634456002773	Predicted integral membrane protein [Function unknown]; Region: COG0392
634456002774	Uncharacterized conserved protein (DUF2156); Region: DUF2156; cl12090
634456002775	Multiple antibiotic transporter [Intracellular trafficking and secretion]; Region: MarC; COG2095
634456002776	Protein involved in catabolism of external DNA [General function prediction only]; Region: ComJ; COG2961
634456002777	UGMP family protein; Validated; Region: PRK09604
634456002778	tRNA threonylcarbamoyl adenosine modification protein YeaZ; Region: T6A_YeaZ; TIGR03725
634456002779	porphobilinogen deaminase; Reviewed; Region: hemC; PRK00072
634456002780	Hydroxymethylbilane synthase (HMBS), also known as porphobilinogen deaminase (PBGD), is an intermediate enzyme in the biosynthetic pathway of tetrapyrrolic ring systems, such as heme, chlorophylls, and vitamin B12. HMBS catalyzes the conversion of...; Region: HMBS; cl17708
634456002781	domain interfaces; other site
634456002782	active site
634456002783	Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in...; Region: HemD; cd06578
634456002784	Uroporphyrinogen-III synthase [Coenzyme metabolism]; Region: HemD; COG1587
634456002785	active site
634456002786	preprotein translocase subunit SecB; Validated; Region: PRK05751
634456002787	SecA binding site; other site
634456002788	Preprotein binding site; other site
634456002789	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
634456002790	catalytic core [active]
634456002791	Tim44-like domain; Region: Tim44; pfam04280
634456002792	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
634456002793	DNA methylase; Region: N6_N4_Mtase; pfam01555
634456002794	Haem-binding domain; Region: Haem_bd; pfam14376
634456002795	Cytochrome c peroxidase [Inorganic ion transport and metabolism]; Region: MauG; COG1858
634456002796	Smr domain; Region: Smr; pfam01713
634456002797	coproporphyrinogen III oxidase; Provisional; Region: PRK05330
634456002798	Coproporphyrinogen III oxidase; Region: Coprogen_oxidas; cl17752
634456002799	Cytochrome b (N-terminus)/b6/petB:  Cytochrome b is a subunit of cytochrome bc1, an 11-subunit mitochondrial respiratory enzyme. Cytochrome b spans the mitochondrial membrane with 8 transmembrane helices (A-H) in eukaryotes. In plants and cyanobacteria; Region: Cytochrome_b_N; cl00859
634456002800	Qi binding site; other site
634456002801	intrachain domain interface; other site
634456002802	interchain domain interface [polypeptide binding]; other site
634456002803	heme bH binding site [chemical binding]; other site
634456002804	heme bL binding site [chemical binding]; other site
634456002805	Qo binding site; other site
634456002806	Cytochrome b(C-terminus)/b6/petD:  Cytochrome b is a subunit of cytochrome bc1, an 11-subunit mitochondrial respiratory enzyme. Cytochrome b spans the mitochondrial membrane with 8 transmembrane helices (A-H) in eukaryotes. In plants and cyanobacteria; Region: cytochrome_b_C; cl00193
634456002807	intrachain domain interface; other site
634456002808	interchain domain interface [polypeptide binding]; other site
634456002809	Qi binding site; other site
634456002810	Qo binding site; other site
634456002811	Cytochrome C1 family; Region: Cytochrom_C1; pfam02167
634456002812	5'-methylthioadenosine phosphorylase; Provisional; Region: PRK08931
634456002813	Protein of unknown function (DUF4232); Region: DUF4232; pfam14016
634456002814	Putative threonine efflux protein [Amino acid transport and metabolism]; Region: RhtB; COG1280
634456002815	NAD(P)H:FMN oxidoreductase family. This domain catalyzes the reduction of flavin, nitrocompound, quinones and azo compounds using NADH or NADPH as an electron donor. The enzyme is a homodimer, and each monomer binds a FMN as co-factor. This family...; Region: NfsB_like_nitroreductase; cd02149
634456002816	FMN binding site [chemical binding]; other site
634456002817	dimer interface [polypeptide binding]; other site
634456002818	ornithine cyclodeaminase; Validated; Region: PRK07340
634456002819	ornithine cyclodeaminase; Validated; Region: PRK06823; cl17400
634456002820	Coniferyl aldehyde dehydrogenase-like; Region: ALDH_CALDH_CalB; cd07133
634456002821	aldehyde dehydrogenase family protein; Provisional; Region: PTZ00381
634456002822	NAD(P) binding site [chemical binding]; other site
634456002823	catalytic residues [active]
634456002824	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
634456002825	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
634456002826	WHG domain; Region: WHG; pfam13305
634456002827	Transposase; Region: HTH_Tnp_1; pfam01527
634456002828	HTH-like domain; Region: HTH_21; pfam13276
634456002829	Integrase core domain; Region: rve; pfam00665
634456002830	Integrase core domain; Region: rve_3; pfam13683
634456002831	Transposase DDE domain group 1; Region: DDE_Tnp_1_4; pfam13701
634456002832	multiple promoter invertase; Provisional; Region: mpi; PRK13413
634456002833	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
634456002834	catalytic residues [active]
634456002835	catalytic nucleophile [active]
634456002836	Presynaptic Site I dimer interface [polypeptide binding]; other site
634456002837	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
634456002838	Synaptic Flat tetramer interface [polypeptide binding]; other site
634456002839	Synaptic Site I dimer interface [polypeptide binding]; other site
634456002840	DNA binding site [nucleotide binding]
634456002841	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
634456002842	DNA-binding interface [nucleotide binding]; DNA binding site
634456002843	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
634456002844	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
634456002845	active site
634456002846	DNA binding site [nucleotide binding]
634456002847	Int/Topo IB signature motif; other site
634456002848	integrase; Provisional; Region: PRK09692
634456002849	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
634456002850	active site
634456002851	Int/Topo IB signature motif; other site
634456002852	Activation domain of S53 peptidases; Region: Pro-peptidase_S53; cl07889
634456002853	Predicted nuclease of the RNAse H fold, HicB family [General    function prediction only]; Region: HicB; COG4226
634456002854	HicB family; Region: HicB; pfam05534
634456002855	Endodeoxyribonuclease RusA; Region: RusA; pfam05866
634456002856	Phage-related minor tail protein; Region: PhageMin_Tail; pfam10145
634456002857	Predicted ATP-binding protein involved in virulence [General function prediction only]; Region: COG3950
634456002858	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
634456002859	Walker A/P-loop; other site
634456002860	ATP binding site [chemical binding]; other site
634456002861	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
634456002862	synthetase active site [active]
634456002863	NTP binding site [chemical binding]; other site
634456002864	metal binding site [ion binding]; metal-binding site
634456002865	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
634456002866	Transposase; Region: HTH_Tnp_1; pfam01527
634456002867	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
634456002868	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
634456002869	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
634456002870	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
634456002871	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
634456002872	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
634456002873	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
634456002874	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: Tra5; COG2801
634456002875	HTH-like domain; Region: HTH_21; pfam13276
634456002876	Integrase core domain; Region: rve; pfam00665
634456002877	Integrase core domain; Region: rve_3; pfam13683
634456002878	Transposase; Region: HTH_Tnp_1; pfam01527
634456002879	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
634456002880	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
634456002881	non-specific DNA binding site [nucleotide binding]; other site
634456002882	salt bridge; other site
634456002883	sequence-specific DNA binding site [nucleotide binding]; other site
634456002884	hypothetical protein; Validated; Region: PRK07078
634456002885	TOPRIM_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of bacterial DnaG-type primases and their homologs. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_primases; cd01029
634456002886	active site
634456002887	metal binding site [ion binding]; metal-binding site
634456002888	interdomain interaction site; other site
634456002889	Topoisomerase-primase domain. This is a nucleotidyl transferase/hydrolase domain found in type IA, type IIA and type IIB topoisomerases, bacterial DnaG-type primases, small primase-like proteins from bacteria and archaea, OLD family nucleases from...; Region: TOPRIM; cl00718
634456002890	Domain of unknown function (DUF927); Region: DUF927; pfam06048
634456002891	Ketopantoate hydroxymethyltransferase (KPHMT) is the first enzyme in the pantothenate biosynthesis pathway. Ketopantoate hydroxymethyltransferase (KPHMT) catalyzes the first committed step in the biosynthesis of pantothenate (vitamin B5), which is a...; Region: KPHMT-like; cd06557
634456002892	active site
634456002893	oligomerization interface [polypeptide binding]; other site
634456002894	metal binding site [ion binding]; metal-binding site
634456002895	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
634456002896	Old yellow enzyme (OYE) YqjM-like FMN binding domain. YqjM is involved in the oxidative stress response of Bacillus subtilis.  Like the other OYE members, each monomer of YqjM contains FMN as a non-covalently bound cofactor and uses NADPH as a reducing...; Region: OYE_YqiM_FMN; cd02932
634456002897	active site
634456002898	FMN binding site [chemical binding]; other site
634456002899	substrate binding site [chemical binding]; other site
634456002900	homotetramer interface [polypeptide binding]; other site
634456002901	catalytic residue [active]
634456002902	Helix-turn-helix domain; Region: HTH_20; pfam12840
634456002903	dimerization interface [polypeptide binding]; other site
634456002904	putative DNA binding site [nucleotide binding]; other site
634456002905	putative Zn2+ binding site [ion binding]; other site
634456002906	Zn-dependent alcohol dehydrogenases [General function prediction only]; Region: AdhP; COG1064
634456002907	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD2; cd08298
634456002908	putative NAD(P) binding site [chemical binding]; other site
634456002909	putative substrate binding site [chemical binding]; other site
634456002910	catalytic Zn binding site [ion binding]; other site
634456002911	structural Zn binding site [ion binding]; other site
634456002912	V8-like Glu-specific endopeptidase [Amino acid transport and metabolism]; Region: COG3591
634456002913	UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs; Region: UDP_G4E_1_SDR_e; cd05247
634456002914	UDP-glucose 4-epimerase [Cell envelope biogenesis, outer membrane]; Region: GalE; COG1087
634456002915	NAD binding site [chemical binding]; other site
634456002916	homodimer interface [polypeptide binding]; other site
634456002917	active site
634456002918	substrate binding site [chemical binding]; other site
634456002919	Domain of unknown function (DUF4175); Region: DUF4175; pfam13779
634456002920	diaminopimelate decarboxylase; Region: lysA; TIGR01048
634456002921	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Diaminopimelate Decarboxylase; Region: PLPDE_III_DapDC; cd06828
634456002922	active site
634456002923	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
634456002924	substrate binding site [chemical binding]; other site
634456002925	catalytic residues [active]
634456002926	dimer interface [polypeptide binding]; other site
634456002927	argininosuccinate lyase; Provisional; Region: PRK00855
634456002928	Argininosuccinate lyase (argininosuccinase, ASAL); Region: Argininosuccinate_lyase; cd01359
634456002929	active sites [active]
634456002930	tetramer interface [polypeptide binding]; other site
634456002931	N-formylglutamate amidohydrolase; Region: FGase; cl01522
634456002932	shikimate 5-dehydrogenase; Reviewed; Region: aroE; PRK00258
634456002933	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
634456002934	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
634456002935	shikimate binding site; other site
634456002936	NAD(P) binding site [chemical binding]; other site
634456002937	Dephospho-CoA kinase [Coenzyme metabolism]; Region: CoaE; COG0237
634456002938	Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022
634456002939	CoA-binding site [chemical binding]; other site
634456002940	ATP-binding [chemical binding]; other site
634456002941	DEDDh 3'-5' exonuclease domain of the epsilon subunit of Escherichia coli DNA polymerase III and similar proteins; Region: DNA_pol_III_epsilon_Ecoli_like; cd06131
634456002942	active site
634456002943	catalytic site [active]
634456002944	substrate binding site [chemical binding]; other site
634456002945	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
634456002946	This family is most closely related to the GT1 family of glycosyltransferases. cap1E in Streptococcus pneumoniae is required for the synthesis of type 1 capsular polysaccharides; Region: GT1_cap1E_like; cd03808
634456002947	putative ADP-binding pocket [chemical binding]; other site
634456002948	Heparinase II/III-like protein; Region: Hepar_II_III; cl15421
634456002949	Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]; Region: Rpe; COG0036
634456002950	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
634456002951	substrate binding site [chemical binding]; other site
634456002952	hexamer interface [polypeptide binding]; other site
634456002953	metal binding site [ion binding]; metal-binding site
634456002954	RNA binding domain of NusB (N protein-Utilization Substance B) and Sun (also known as RrmB or Fmu) proteins. This family includes two orthologous groups exemplified by the transcription termination factor NusB and the N-terminal domain of the...; Region: NusB_Sun; cl00223
634456002955	putative RNA binding site [nucleotide binding]; other site
634456002956	16S rRNA methyltransferase B; Provisional; Region: PRK10901
634456002957	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
634456002958	S-adenosylmethionine binding site [chemical binding]; other site
634456002959	phosphoribosylglycinamide formyltransferase; Reviewed; Region: purN; PRK05647
634456002960	Phosphoribosylglycinamide formyltransferase (GAR transformylase, GART); Region: FMT_core_GART; cd08645
634456002961	active site
634456002962	substrate binding site [chemical binding]; other site
634456002963	cosubstrate binding site; other site
634456002964	catalytic site [active]
634456002965	phosphoribosylaminoimidazole synthetase; Provisional; Region: PRK05385
634456002966	PurM (Aminoimidazole Ribonucleotide [AIR] synthetase), one of eleven enzymes required for purine biosynthesis, catalyzes the conversion of formylglycinamide ribonucleotide (FGAM) and ATP to AIR, ADP, and Pi, the fifth step in de novo purine biosynthesis; Region: PurM; cd02196
634456002967	dimerization interface [polypeptide binding]; other site
634456002968	putative ATP binding site [chemical binding]; other site
634456002969	ATPase involved in DNA replication initiation [DNA replication, recombination, and repair]; Region: DnaA; COG0593
634456002970	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
634456002971	polyphosphate kinase; Provisional; Region: PRK05443
634456002972	Polyphosphate kinase N-terminal domain; Region: PP_kinase_N; pfam13089
634456002973	Polyphosphate kinase middle domain; Region: PP_kinase; pfam02503
634456002974	Catalytic C-terminal domain, first repeat, of Pseudomonas aeruginosa polyphosphate kinase 1 and similar proteins; Region: PLDc_PaPPK1_C1_like; cd09165
634456002975	putative domain interface [polypeptide binding]; other site
634456002976	putative active site [active]
634456002977	catalytic site [active]
634456002978	Catalytic C-terminal domain, second repeat, of Pseudomonas aeruginosa polyphosphate kinase 1 and similar proteins; Region: PLDc_PaPPK1_C2_like; cd09168
634456002979	putative domain interface [polypeptide binding]; other site
634456002980	putative active site [active]
634456002981	catalytic site [active]
634456002982	exopolyphosphatase; Region: exo_poly_only; TIGR03706
634456002983	Ppx/GppA phosphatase family; Region: Ppx-GppA; pfam02541
634456002984	Cache domain; Region: Cache_1; pfam02743
634456002985	cyclase homology domain; Region: CHD; cd07302
634456002986	nucleotidyl binding site; other site
634456002987	metal binding site [ion binding]; metal-binding site
634456002988	dimer interface [polypeptide binding]; other site
634456002989	Permease; Region: Permease; pfam02405
634456002990	lipoprotein releasing system, ATP-binding protein; Region: LolD_lipo_ex; TIGR02211
634456002991	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
634456002992	Q-loop/lid; other site
634456002993	ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2C; COG1463
634456002994	mce related protein; Region: MCE; pfam02470
634456002995	sugar binding site [chemical binding]; other site
634456002996	F5/8 type C domain; Region: F5_F8_type_C; pfam00754
634456002997	Inward rectifier potassium channel; Region: IRK; pfam01007
634456002998	Fusaric acid resistance protein family; Region: FUSC; pfam04632
634456002999	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
634456003000	Fusaric acid resistance protein family; Region: FUSC; pfam04632
634456003001	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
634456003002	Bacterial protein of unknown function (DUF937); Region: DUF937; cl01528
634456003003	Cytochrome c biogenesis factor [Posttranslational modification, protein turnover, chaperones]; Region: COG4235
634456003004	cytochrome c-type biogenesis protein CcmI; Region: cytochro_ccmI; TIGR03142
634456003005	Cytochrome C biogenesis protein; Region: CcmH; pfam03918
634456003006	periplasmic protein thiol:disulfide oxidoreductases, DsbE subfamily; Region: dsbE; TIGR00385
634456003007	TlpA-like family, DsbE (also known as CcmG and CycY) subfamily; DsbE is a membrane-anchored, periplasmic TRX-like reductase containing a CXXC motif that specifically donates reducing equivalents to apocytochrome c via CcmH, another cytochrome c...; Region: TlpA_like_DsbE; cd03010
634456003008	catalytic residues [active]
634456003009	central insert; other site
634456003010	Cytochrome c biogenesis factor [Posttranslational modification, protein turnover, chaperones]; Region: CcmF; COG1138
634456003011	cytochrome c-type biogenesis protein CcmE; Reviewed; Region: PRK13254
634456003012	heme exporter protein CcmC; Region: ccmC; TIGR01191
634456003013	YciI-like protein; Reviewed; Region: PRK12863
634456003014	EVE domain; Region: EVE; pfam01878
634456003015	Putative phosphatase (DUF442); Region: DUF442; cl17385
634456003016	EcsC protein family; Region: EcsC; pfam12787
634456003017	Phosphoglycerate dehydrogenase and related dehydrogenases [Amino acid transport and metabolism]; Region: SerA; COG0111
634456003018	D-glycerate dehydrogenase/hydroxypyruvate reductase (GDH); Region: GDH; cd05301
634456003019	dimerization interface [polypeptide binding]; other site
634456003020	ligand binding site [chemical binding]; other site
634456003021	NADP binding site [chemical binding]; other site
634456003022	catalytic site [active]
634456003023	leucyl/phenylalanyl-tRNA--protein transferase; Reviewed; Region: aat; PRK00301
634456003024	Domain of unknown function (DUF4412); Region: DUF4412; pfam14371
634456003025	Domain of unknown function (DUF4412); Region: DUF4412; pfam14371
634456003026	Protein of unknown function; Region: DUF3971; pfam13116
634456003027	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
634456003028	bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase; Provisional; Region: PRK14108
634456003029	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
634456003030	metal binding triad; other site
634456003031	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
634456003032	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
634456003033	metal binding triad; other site
634456003034	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
634456003035	Peroxiredoxin (PRX) family, Bacterioferritin comigratory protein (BCP) subfamily; composed of thioredoxin-dependent thiol peroxidases, widely expressed in pathogenic bacteria, that protect cells against toxicity from reactive oxygen species by reducing...; Region: PRX_BCP; cd03017
634456003036	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
634456003037	catalytic triad [active]
634456003038	alpha-ketoglutarate transporter; Provisional; Region: PRK10406
634456003039	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
634456003040	putative substrate translocation pore; other site
634456003041	RmuC family; Region: RmuC; pfam02646
634456003042	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
634456003043	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
634456003044	active site
634456003045	phosphorylation site [posttranslational modification]
634456003046	intermolecular recognition site; other site
634456003047	dimerization interface [polypeptide binding]; other site
634456003048	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
634456003049	DNA binding site [nucleotide binding]
634456003050	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
634456003051	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
634456003052	dimerization interface [polypeptide binding]; other site
634456003053	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
634456003054	ATP binding site [chemical binding]; other site
634456003055	Mg2+ binding site [ion binding]; other site
634456003056	G-X-G motif; other site
634456003057	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
634456003058	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
634456003059	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
634456003060	HlyD family secretion protein; Region: HlyD_3; pfam13437
634456003061	efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family; Region: outer_NodT; TIGR01845
634456003062	50S ribosomal protein L11; Validated; Region: rplK; PRK00140
634456003063	Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349
634456003064	23S rRNA interface [nucleotide binding]; other site
634456003065	L7/L12 interface [polypeptide binding]; other site
634456003066	putative thiostrepton binding site; other site
634456003067	L25 interface [polypeptide binding]; other site
634456003068	Ribosomal protein L1.  The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA.  In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403
634456003069	mRNA/rRNA interface [nucleotide binding]; other site
634456003070	Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797
634456003071	23S rRNA interface [nucleotide binding]; other site
634456003072	Interface with L7/L12 ribosomal proteins [polypeptide binding]; other site
634456003073	Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cd00387
634456003074	L11 interface [polypeptide binding]; other site
634456003075	putative EF-Tu interaction site [polypeptide binding]; other site
634456003076	putative EF-G interaction site [polypeptide binding]; other site
634456003077	DNA-directed RNA polymerase subunit beta; Reviewed; Region: rpoB; PRK00405
634456003078	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585
634456003079	RNA polymerase Rpb2, domain 2; Region: RNA_pol_Rpb2_2; pfam04561
634456003080	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
634456003081	RNA polymerase Rpb2, domain 6; Region: RNA_pol_Rpb2_6; pfam00562
634456003082	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
634456003083	RPB1 interaction site [polypeptide binding]; other site
634456003084	RPB11 interaction site [polypeptide binding]; other site
634456003085	RPB10 interaction site [polypeptide binding]; other site
634456003086	RPB3 interaction site [polypeptide binding]; other site
634456003087	RNA polymerase Rpb1, domain 1; Region: RNA_pol_Rpb1_1; pfam04997
634456003088	DNA-directed RNA polymerase, beta' subunit/160 kD subunit [Transcription]; Region: RpoC; COG0086
634456003089	RNA polymerase I subunit A N-terminus; Region: RPOLA_N; smart00663
634456003090	RNA polymerase Rpb1, domain 3; Region: RNA_pol_Rpb1_3; pfam04983
634456003091	RNA polymerase Rpb1, domain 4; Region: RNA_pol_Rpb1_4; pfam05000
634456003092	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
634456003093	Rpb1 - Rpb6 interaction site [polypeptide binding]; other site
634456003094	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
634456003095	DNA binding site [nucleotide binding]
634456003096	Rpb1 (beta') - Rpb2 (beta) interaction site [polypeptide binding]; other site
634456003097	S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; Region: Ribosomal_S12; cd03368
634456003098	S17 interaction site [polypeptide binding]; other site
634456003099	S8 interaction site; other site
634456003100	16S rRNA interaction site [nucleotide binding]; other site
634456003101	streptomycin interaction site [chemical binding]; other site
634456003102	23S rRNA interaction site [nucleotide binding]; other site
634456003103	aminoacyl-tRNA interaction site (A-site) [nucleotide binding]; other site
634456003104	30S ribosomal protein S7; Validated; Region: PRK05302
634456003105	elongation factor Tu; Reviewed; Region: PRK00049
634456003106	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
634456003107	G1 box; other site
634456003108	GEF interaction site [polypeptide binding]; other site
634456003109	GTP/Mg2+ binding site [chemical binding]; other site
634456003110	Switch I region; other site
634456003111	G2 box; other site
634456003112	G3 box; other site
634456003113	Switch II region; other site
634456003114	G4 box; other site
634456003115	G5 box; other site
634456003116	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
634456003117	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
634456003118	Antibiotic Binding Site [chemical binding]; other site
634456003119	30S ribosomal protein S10; Reviewed; Region: rpsJ; PRK00596
634456003120	50S ribosomal protein L3; Validated; Region: rplC; PRK00001
634456003121	50S ribosomal protein L4; Provisional; Region: rplD; PRK05319
634456003122	50S ribosomal protein L23; Reviewed; Region: rplW; PRK05738
634456003123	50S ribosomal protein L2; Validated; Region: rplB; PRK09374
634456003124	Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181
634456003125	Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947
634456003126	30S ribosomal protein S19; Reviewed; Region: rpsS; PRK00357
634456003127	Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cd00336
634456003128	putative translocon binding site; other site
634456003129	protein-rRNA interface [nucleotide binding]; other site
634456003130	30S ribosomal protein S3; Reviewed; Region: rpsC; PRK00310
634456003131	K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3  is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel.  The KH...; Region: 30S_S3_KH; cd02412
634456003132	G-X-X-G motif; other site
634456003133	Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189
634456003134	Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433
634456003135	23S rRNA interface [nucleotide binding]; other site
634456003136	5S rRNA interface [nucleotide binding]; other site
634456003137	putative antibiotic binding site [chemical binding]; other site
634456003138	L25 interface [polypeptide binding]; other site
634456003139	L27 interface [polypeptide binding]; other site
634456003140	Ribosomal L29 protein/HIP.  L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals.  L29 is located on the surface of the large ribosomal subunit, where it...; Region: Ribosomal_L29_HIP; cd00427
634456003141	23S rRNA interface [nucleotide binding]; other site
634456003142	putative translocon interaction site; other site
634456003143	signal recognition particle (SRP54) interaction site; other site
634456003144	L23 interface [polypeptide binding]; other site
634456003145	trigger factor interaction site; other site
634456003146	30S ribosomal protein S17; Reviewed; Region: rpsQ; PRK05610
634456003147	50S ribosomal protein L14; Validated; Region: rplN; PRK05483
634456003148	50S ribosomal protein L24; Reviewed; Region: rplX; PRK00004
634456003149	KOW motif of Ribosomal Protein L26; Region: KOW_RPL26; cd06089
634456003150	RNA binding site [nucleotide binding]; other site
634456003151	50S ribosomal protein L5; Validated; Region: rplE; PRK00010
634456003152	Ribosomal protein L5; Region: Ribosomal_L5; pfam00281
634456003153	ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673
634456003154	30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08881
634456003155	30S ribosomal protein S8; Validated; Region: rpsH; PRK00136
634456003156	50S ribosomal protein L6; Validated; Region: rplF; PRK05498
634456003157	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
634456003158	Ribosomal L18/L5e:  L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432
634456003159	5S rRNA interface [nucleotide binding]; other site
634456003160	23S rRNA interface [nucleotide binding]; other site
634456003161	L5 interface [polypeptide binding]; other site
634456003162	30S ribosomal protein S5; Validated; Region: rpsE; PRK00550
634456003163	Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333
634456003164	Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719
634456003165	Ribosomal protein L30, which is found in eukaryotes and prokaryotes but not in archaea, is one of the smallest ribosomal proteins with a molecular mass of about 7kDa. L30 binds the 23SrRNA as well as the 5S rRNA and is one of five ribosomal proteins that...; Region: Ribosomal_L30; cd01658
634456003166	23S rRNA binding site [nucleotide binding]; other site
634456003167	50S ribosomal protein L15; Reviewed; Region: rplO; PRK05592
634456003168	preprotein translocase subunit SecY; Reviewed; Region: secY; PRK09204
634456003169	SecY translocase; Region: SecY; pfam00344
634456003170	adenylate kinase; Reviewed; Region: adk; PRK00279
634456003171	Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428
634456003172	AMP-binding site [chemical binding]; other site
634456003173	ATP-AMP (Ap5A)-binding site [chemical binding]; other site
634456003174	Ribosomal protein S13 [Translation, ribosomal structure and biogenesis]; Region: RpsM; COG0099
634456003175	30S ribosomal protein S13; Region: bact_S13; TIGR03631
634456003176	30S ribosomal protein S11; Validated; Region: PRK05309
634456003177	DNA-directed RNA polymerase subunit alpha; Provisional; Region: PRK05182
634456003178	N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928
634456003179	alphaNTD - beta interaction site [polypeptide binding]; other site
634456003180	alphaNTD homodimer interface [polypeptide binding]; other site
634456003181	alphaNTD - beta' interaction site [polypeptide binding]; other site
634456003182	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118
634456003183	50S ribosomal protein L17; Validated; Region: rplQ; PRK05591
634456003184	ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components [Inorganic ion transport and metabolism]; Region: TauA; COG0715
634456003185	NMT1-like family; Region: NMT1_2; pfam13379
634456003186	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
634456003187	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
634456003188	dimer interface [polypeptide binding]; other site
634456003189	conserved gate region; other site
634456003190	putative PBP binding loops; other site
634456003191	ABC-ATPase subunit interface; other site
634456003192	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: TauB; COG1116
634456003193	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
634456003194	Walker A/P-loop; other site
634456003195	ATP binding site [chemical binding]; other site
634456003196	Q-loop/lid; other site
634456003197	ABC transporter signature motif; other site
634456003198	Walker B; other site
634456003199	D-loop; other site
634456003200	H-loop/switch region; other site
634456003201	efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family; Region: outer_NodT; TIGR01845
634456003202	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
634456003203	Protein export membrane protein; Region: SecD_SecF; cl14618
634456003204	multidrug efflux system subunit MdtB; Provisional; Region: PRK10503
634456003205	Protein export membrane protein; Region: SecD_SecF; cl14618
634456003206	multidrug efflux system subunit MdtA; Provisional; Region: PRK11556
634456003207	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
634456003208	HlyD family secretion protein; Region: HlyD_3; pfam13437
634456003209	putative transporter; Provisional; Region: PRK10504
634456003210	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
634456003211	putative substrate translocation pore; other site
634456003212	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
634456003213	CsbD-like; Region: CsbD; pfam05532
634456003214	Bacterial protein of unknown function (DUF883); Region: DUF883; cl01888
634456003215	bacterial Ribonuclease HII-like; Region: RNase_HII_bacteria_HII_like; cd07182
634456003216	RNA/DNA hybrid binding site [nucleotide binding]; other site
634456003217	active site
634456003218	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
634456003219	DNA methylase; Region: N6_N4_Mtase; pfam01555
634456003220	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
634456003221	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
634456003222	Protein of unknown function (DUF1355); Region: DUF1355; cl17712
634456003223	A4 beta-galactosidase middle domain: a type 1 glutamine amidotransferase (GATase1)-like domain; Region: A4_beta-galactosidase_middle_domain; cd03143
634456003224	Domain of unknown function (DUF4159); Region: DUF4159; pfam13709
634456003225	Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) [General function prediction only]; Region: COG1721
634456003226	Protein of unknown function DUF58; Region: DUF58; pfam01882
634456003227	MoxR-like ATPases [General function prediction only]; Region: COG0714
634456003228	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
634456003229	Protein of unknown function (DUF1285); Region: DUF1285; pfam06938
634456003230	tRNA nucleotidyltransferase/poly(A) polymerase [Translation, ribosomal structure and biogenesis]; Region: PcnB; COG0617
634456003231	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
634456003232	active site
634456003233	NTP binding site [chemical binding]; other site
634456003234	metal binding triad [ion binding]; metal-binding site
634456003235	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
634456003236	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
634456003237	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
634456003238	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
634456003239	Walker A/P-loop; other site
634456003240	ATP binding site [chemical binding]; other site
634456003241	Q-loop/lid; other site
634456003242	ABC transporter signature motif; other site
634456003243	Walker B; other site
634456003244	D-loop; other site
634456003245	H-loop/switch region; other site
634456003246	Multidrug resistance efflux pump [Defense mechanisms]; Region: EmrA; COG1566
634456003247	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
634456003248	E3 interaction surface; other site
634456003249	lipoyl attachment site [posttranslational modification]; other site
634456003250	HlyD family secretion protein; Region: HlyD_3; pfam13437
634456003251	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
634456003252	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
634456003253	putative substrate translocation pore; other site
634456003254	Diadenosine tetraphosphate (Ap4A) hydrolase is a member of the Nudix hydrolase superfamily. Members of this family are well represented in a variety of prokaryotic and eukaryotic organisms. Phylogenetic analysis reveals two distinct subgroups where plant...; Region: Ap4A_hydrolase_plant_like; cd03671
634456003255	putative active site [active]
634456003256	Ap4A binding site [chemical binding]; other site
634456003257	nudix motif; other site
634456003258	putative metal binding site [ion binding]; other site
634456003259	Putative catalytic domain of family 2 polysaccharide deacetylases (DACs) from bacteria; Region: CE4_DAC2; cd10936
634456003260	NodB motif; other site
634456003261	putative active site [active]
634456003262	putative catalytic site [active]
634456003263	Zn binding site [ion binding]; other site
634456003264	C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526
634456003265	C-terminal peptidase (prc); Region: prc; TIGR00225
634456003266	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
634456003267	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
634456003268	Catalytic dyad [active]
634456003269	Membrane-bound metallopeptidase [Cell division and chromosome partitioning]; Region: COG4942
634456003270	Peptidase family M23; Region: Peptidase_M23; pfam01551
634456003271	Phosphoglyceromutase [Carbohydrate transport and metabolism]; Region: GpmI; COG0696
634456003272	phosphoglyceromutase; Provisional; Region: PRK05434
634456003273	threonine dehydratase; Provisional; Region: PRK07334
634456003274	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
634456003275	tetramer interface [polypeptide binding]; other site
634456003276	pyridoxal 5'-phosphate binding site [chemical binding]; other site
634456003277	catalytic residue [active]
634456003278	C-terminal ACT domain of biodegradative (catabolic) threonine dehydratase II (ThrD-II) and other related ACT domains; Region: ACT_ThrD-II-like; cd04886
634456003279	transcription elongation factor GreA; Reviewed; Region: greA; PRK00226
634456003280	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
634456003281	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
634456003282	carbamoyl phosphate synthase large subunit; Reviewed; Region: carB; PRK05294
634456003283	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
634456003284	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
634456003285	Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; pfam02787
634456003286	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
634456003287	ATP-grasp domain; Region: ATP-grasp_4; cl17255
634456003288	Methylglyoxal synthase-like domain from type II glutamine-dependent carbamoyl phosphate synthetase (CSP). CSP, a CarA and CarB heterodimer, catalyzes the production of carbamoyl phosphate which is subsequently employed in the metabolic pathways...; Region: MGS_CPS_II; cd01424
634456003289	IMP binding site; other site
634456003290	dimer interface [polypeptide binding]; other site
634456003291	partial ornithine binding site; other site
634456003292	carbamoyl phosphate synthase small subunit; Reviewed; Region: PRK12564
634456003293	Carbamoyl-phosphate synthase small chain, CPSase domain; Region: CPSase_sm_chain; smart01097
634456003294	Small chain of the glutamine-dependent form of carbamoyl phosphate synthase, CPSase II; Region: GATase1_CPSase; cd01744
634456003295	catalytic site [active]
634456003296	subunit interface [polypeptide binding]; other site
634456003297	Yqey-like protein; Region: YqeY; pfam09424
634456003298	DNA primase; Validated; Region: dnaG; PRK05667
634456003299	CHC2 zinc finger; Region: zf-CHC2; pfam01807
634456003300	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
634456003301	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
634456003302	active site
634456003303	metal binding site [ion binding]; metal-binding site
634456003304	interdomain interaction site; other site
634456003305	RNA polymerase sigma factor RpoD; Validated; Region: PRK05658
634456003306	Sigma-70 factor, region 1.1; Region: Sigma70_r1_1; pfam03979
634456003307	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
634456003308	Sigma-70, non-essential region; Region: Sigma70_ner; pfam04546
634456003309	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
634456003310	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
634456003311	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
634456003312	DNA binding residues [nucleotide binding]
634456003313	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
634456003314	30S ribosomal protein S6; Reviewed; Region: rpsF; PRK00453
634456003315	30S ribosomal protein S18; Reviewed; Region: rpsR; PRK00391
634456003316	50S ribosomal protein L9; Reviewed; Region: rplI; PRK00137
634456003317	Ribosomal protein L9, N-terminal domain; Region: Ribosomal_L9_N; pfam01281
634456003318	Ribosomal protein L9, C-terminal domain; Region: Ribosomal_L9_C; pfam03948
634456003319	Cyclopropane fatty acid synthase and related methyltransferases [Cell envelope biogenesis, outer membrane]; Region: Cfa; COG2230
634456003320	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
634456003321	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
634456003322	S-adenosylmethionine binding site [chemical binding]; other site
634456003323	Dimethyladenosine transferase (rRNA methylation) [Translation, ribosomal structure and biogenesis]; Region: KsgA; COG0030
634456003324	16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Reviewed; Region: ksgA; PRK00274
634456003325	SurA N-terminal domain; Region: SurA_N; pfam09312
634456003326	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
634456003327	Organic solvent tolerance protein OstA [Cell envelope biogenesis, outer membrane]; Region: Imp; COG1452
634456003328	OstA-like protein; Region: OstA; cl00844
634456003329	Organic solvent tolerance protein; Region: OstA_C; pfam04453
634456003330	Predicted permeases [General function prediction only]; Region: COG0795
634456003331	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
634456003332	Predicted permeases [General function prediction only]; Region: COG0795
634456003333	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
634456003334	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
634456003335	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
634456003336	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
634456003337	Walker A/P-loop; other site
634456003338	ATP binding site [chemical binding]; other site
634456003339	Q-loop/lid; other site
634456003340	ABC transporter signature motif; other site
634456003341	Walker B; other site
634456003342	D-loop; other site
634456003343	H-loop/switch region; other site
634456003344	Transcriptional regulators [Transcription]; Region: GntR; COG1802
634456003345	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
634456003346	DNA-binding site [nucleotide binding]; DNA binding site
634456003347	FCD domain; Region: FCD; pfam07729
634456003348	cell division topological specificity factor MinE; Reviewed; Region: minE; PRK00296
634456003349	Septum formation inhibitor-activating ATPase [Cell division and chromosome partitioning]; Region: MinD; COG2894
634456003350	Bacterial cell division requires the formation of a septum at mid-cell. The site is determined by the min operon products MinC, MinD and MinE. MinC is a nonspecific inhibitor of the septum protein FtsZ. MinE is the supressor of MinC. MinD plays a pivotal...; Region: MinD; cd02036
634456003351	Switch I; other site
634456003352	Switch II; other site
634456003353	septum formation inhibitor; Reviewed; Region: minC; PRK05177
634456003354	Septum formation inhibitor MinC, N-terminal domain; Region: MinC_N; pfam05209
634456003355	Septum formation inhibitor MinC, C-terminal domain; Region: MinC_C; pfam03775
634456003356	Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625
634456003357	Glutathione S-transferase (GST) family, N-terminal domain; a large, diverse group of cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of  glutathione (GSH) with a wide range of endogenous and xenobiotic...; Region: GST_N_family; cd00570
634456003358	C-terminal domain interface [polypeptide binding]; other site
634456003359	GSH binding site (G-site) [chemical binding]; other site
634456003360	dimer interface [polypeptide binding]; other site
634456003361	C-terminal, alpha helical domain of the Glutathione S-transferase family; Region: GST_C_family; cd00299
634456003362	N-terminal domain interface [polypeptide binding]; other site
634456003363	dimer interface [polypeptide binding]; other site
634456003364	substrate binding pocket (H-site) [chemical binding]; other site
634456003365	Predicted flavoproteins [General function prediction only]; Region: COG2081
634456003366	Predicted methyltransferases [General function prediction only]; Region: COG0313
634456003367	Ribosomal RNA small subunit methyltransferase I, also known as rRNA (cytidine-2'-O-)-methyltransferase RsmI; Region: RsmI; cd11648
634456003368	putative SAM binding site [chemical binding]; other site
634456003369	putative homodimer interface [polypeptide binding]; other site
634456003370	Periplasmic binding component of lipoprotein LppC, an immunodominant antigen; Region: PBP1_YraM_LppC_lipoprotein_like; cd06339
634456003371	putative ligand binding site [chemical binding]; other site
634456003372	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
634456003373	TPR motif; other site
634456003374	TPR repeat; Region: TPR_11; pfam13414
634456003375	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
634456003376	TPR motif; other site
634456003377	binding surface
634456003378	TPR repeat; Region: TPR_11; pfam13414
634456003379	CarD-like/TRCF domain; Region: CarD_CdnL_TRCF; cl00588
634456003380	Bestrophin, RFP-TM, chloride channel; Region: Bestrophin; pfam01062
634456003381	S-formylglutathione hydrolase; Region: fghA_ester_D; TIGR02821
634456003382	S-formylglutathione hydrolase; Region: PLN02442
634456003383	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
634456003384	putative active site [active]
634456003385	cell division ABC transporter subunit FtsX; Provisional; Region: ftsX; PRK11026
634456003386	Predicted ATPase involved in cell division [Cell division and chromosome partitioning]; Region: FtsE; COG2884
634456003387	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
634456003388	Walker A/P-loop; other site
634456003389	ATP binding site [chemical binding]; other site
634456003390	Q-loop/lid; other site
634456003391	ABC transporter signature motif; other site
634456003392	Walker B; other site
634456003393	D-loop; other site
634456003394	H-loop/switch region; other site
634456003395	zinc-ribbon domain; Region: zinc_ribbon_4; pfam13717
634456003396	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
634456003397	active site
634456003398	phosphorylation site [posttranslational modification]
634456003399	intermolecular recognition site; other site
634456003400	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
634456003401	active site
634456003402	phosphorylation site [posttranslational modification]
634456003403	intermolecular recognition site; other site
634456003404	dimerization interface [polypeptide binding]; other site
634456003405	Winged helix-turn helix; Region: HTH_29; pfam13551
634456003406	Integrase core domain; Region: rve; pfam00665
634456003407	Integrase core domain; Region: rve_3; pfam13683
634456003408	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
634456003409	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
634456003410	ATP binding site [chemical binding]; other site
634456003411	Mg2+ binding site [ion binding]; other site
634456003412	G-X-G motif; other site
634456003413	Response regulator receiver domain; Region: Response_reg; pfam00072
634456003414	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
634456003415	active site
634456003416	phosphorylation site [posttranslational modification]
634456003417	intermolecular recognition site; other site
634456003418	dimerization interface [polypeptide binding]; other site
634456003419	PAS fold; Region: PAS_4; pfam08448
634456003420	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
634456003421	dimer interface [polypeptide binding]; other site
634456003422	phosphorylation site [posttranslational modification]
634456003423	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
634456003424	ATP binding site [chemical binding]; other site
634456003425	Mg2+ binding site [ion binding]; other site
634456003426	G-X-G motif; other site
634456003427	Response regulator receiver domain; Region: Response_reg; pfam00072
634456003428	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
634456003429	active site
634456003430	phosphorylation site [posttranslational modification]
634456003431	intermolecular recognition site; other site
634456003432	dimerization interface [polypeptide binding]; other site
634456003433	Protease HslV and the ATPase/chaperone HslU are part of an ATP-dependent proteolytic system that is the prokaryotic homolog of the proteasome. HslV is a dimer of hexamers (a dodecamer) that forms a central proteolytic chamber with active sites on the...; Region: protease_HslV; cd01913
634456003434	active site
634456003435	HslU subunit interaction site [polypeptide binding]; other site
634456003436	ATP-dependent protease ATP-binding subunit HslU; Provisional; Region: hslU; PRK05201
634456003437	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
634456003438	Walker A motif; other site
634456003439	ATP binding site [chemical binding]; other site
634456003440	AAA domain (Cdc48 subfamily); Region: AAA_2; pfam07724
634456003441	Walker B motif; other site
634456003442	arginine finger; other site
634456003443	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
634456003444	Cysteine desulfurase SufE subunit [Posttranslational modification, protein turnover, chaperones]; Region: sufE; COG2166
634456003445	Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs [Energy production and conversion]; Region: CoxL; COG1529
634456003446	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Region: Ald_Xan_dh_C; smart01008
634456003447	Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738
634456003448	Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738
634456003449	4-hydroxybenzoyl-CoA reductase, gamma subunit; Region: 4hydroxCoAred; TIGR03193
634456003450	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
634456003451	catalytic loop [active]
634456003452	iron binding site [ion binding]; other site
634456003453	[2Fe-2S] binding domain; Region: Fer2_2; pfam01799
634456003454	Cytochrome c; Region: Cytochrom_C; pfam00034
634456003455	Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010
634456003456	Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010
634456003457	Cytochrome c; Region: Cytochrom_C; pfam00034
634456003458	Mannitol-1-phosphate/altronate dehydrogenases [Carbohydrate transport and metabolism]; Region: MtlD; COG0246
634456003459	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
634456003460	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
634456003461	50S ribosomal protein L35; Reviewed; Region: rpmI; PRK00172
634456003462	Ribosomal protein L20; Region: Ribosomal_L20; cd07026
634456003463	23S rRNA binding site [nucleotide binding]; other site
634456003464	L21 binding site [polypeptide binding]; other site
634456003465	L13 binding site [polypeptide binding]; other site
634456003466	phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488
634456003467	Aminoacyl tRNA synthetase class II, N-terminal domain; Region: Phe_tRNA-synt_N; pfam02912
634456003468	Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496
634456003469	dimer interface [polypeptide binding]; other site
634456003470	motif 1; other site
634456003471	active site
634456003472	motif 2; other site
634456003473	motif 3; other site
634456003474	phenylalanyl-tRNA synthetase subunit beta; Reviewed; Region: pheT; PRK00629
634456003475	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
634456003476	putative tRNA-binding site [nucleotide binding]; other site
634456003477	B3/4 domain; Region: B3_4; pfam03483
634456003478	tRNA synthetase B5 domain; Region: B5; smart00874
634456003479	Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA,  PheRS is an...; Region: PheRS_beta_core; cd00769
634456003480	motif 1; other site
634456003481	dimer interface [polypeptide binding]; other site
634456003482	motif 3; other site
634456003483	motif 2; other site
634456003484	Ferredoxin-fold anticodon binding domain; Region: FDX-ACB; smart00896
634456003485	PBP superfamily domain; Region: PBP_like_2; cl17296
634456003486	The substrate-binding domain of an oligopeptide binding protein (OppA2) from the biosynthesis pathway of the beta-lactamase inhibitor clavulanic acid contains the type 2 periplasmic binding fold; Region: PBP2_clavulanate_OppA2; cd08506
634456003487	peptide binding site [polypeptide binding]; other site
634456003488	Bacterial extracellular solute-binding proteins, family 5 Middle; Region: SBP_bac_5; pfam00496
634456003489	NhaP-type Na+/H+ and K+/H+ antiporters [Inorganic ion transport and metabolism]; Region: NhaP; COG0025
634456003490	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
634456003491	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
634456003492	ligand binding site [chemical binding]; other site
634456003493	flexible hinge region; other site
634456003494	Uncharacterized conserved protein [Function unknown]; Region: HdeD; COG3247
634456003495	30S ribosomal protein S4; Validated; Region: rpsD; PRK05327
634456003496	Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163
634456003497	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
634456003498	RNA binding surface [nucleotide binding]; other site
634456003499	Peptide chain release factor RF-3 [Translation, ribosomal structure and biogenesis]; Region: PrfC; COG4108
634456003500	Release Factor 3 (RF3) protein involved in the terminal step of translocation in bacteria; Region: RF3; cd04169
634456003501	G1 box; other site
634456003502	putative GEF interaction site [polypeptide binding]; other site
634456003503	GTP/Mg2+ binding site [chemical binding]; other site
634456003504	Switch I region; other site
634456003505	G2 box; other site
634456003506	G3 box; other site
634456003507	Switch II region; other site
634456003508	G4 box; other site
634456003509	G5 box; other site
634456003510	RF3_II: this subfamily represents the domain II of bacterial Release Factor 3 (RF3). Termination of protein synthesis by the ribosome requires two release factor (RF) classes. The class II RF3 is a GTPase that removes class I RFs (RF1 or RF2) from the...; Region: RF3_II; cd03689
634456003511	hypothetical protein; Provisional; Region: PRK08999
634456003512	Isocitrate/isopropylmalate dehydrogenase; Region: Iso_dh; cl00445
634456003513	tartrate dehydrogenase; Region: TTC; TIGR02089
634456003514	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
634456003515	Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006
634456003516	X-Prolyl Aminopeptidase 2. E.C. 3.4.11.9. Also known as X-Pro aminopeptidase, proline aminopeptidase, aminopeptidase P, and aminoacylproline aminopeptidase. Catalyses release of any N-terminal amino acid, including proline, that is linked with proline; Region: APP; cd01085
634456003517	active site
634456003518	Ribosomal protein L11 methyltransferase (PrmA); Region: PrmA; pfam06325
634456003519	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
634456003520	S-adenosylmethionine binding site [chemical binding]; other site
634456003521	ATP-dependent DNA helicase PcrA; Region: pcrA; TIGR01073
634456003522	Part of AAA domain; Region: AAA_19; pfam13245
634456003523	Family description; Region: UvrD_C_2; pfam13538
634456003524	DNA repair protein radc; Region: radc; TIGR00608
634456003525	Mpr1p, Pad1p N-terminal (MPN) domains; Region: MPN; cl13996
634456003526	DNA repair protein radc; Region: radc; TIGR00608
634456003527	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
634456003528	MPN+ (JAMM) motif; other site
634456003529	Zinc-binding site [ion binding]; other site
634456003530	phosphoribosylaminoimidazole carboxylase ATPase subunit; Reviewed; Region: PRK06019
634456003531	ATP-grasp domain; Region: ATP-grasp; pfam02222
634456003532	AIR carboxylase; Region: AIRC; pfam00731
634456003533	Protein of unknown function (DUF465); Region: DUF465; cl01070
634456003534	Protein of unknown function (DUF1013); Region: DUF1013; pfam06242
634456003535	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
634456003536	Alpha-crystallin domain (ACD) found in Escherichia coli inclusion body-associated proteins IbpA and IbpB, and similar proteins.  IbpA and IbpB are 16 kDa small heat shock proteins (sHsps). sHsps are molecular chaperones that suppress protein aggregation...; Region: ACD_IbpA-B_like; cd06470
634456003537	putative dimer interface [polypeptide binding]; other site
634456003538	50S ribosomal protein L31; Reviewed; Region: rpmE; PRK00528
634456003539	large-conductance mechanosensitive channel; Provisional; Region: mscL; PRK13952
634456003540	large-conductance mechanosensitive channel; Reviewed; Region: mscL; PRK00567
634456003541	preprotein translocase subunit SecF; Reviewed; Region: secF; PRK13022
634456003542	SecD/SecF GG Motif; Region: Sec_GG; pfam07549
634456003543	Protein export membrane protein; Region: SecD_SecF; pfam02355
634456003544	preprotein translocase subunit SecD; Reviewed; Region: secD; PRK05812
634456003545	SecD/SecF GG Motif; Region: Sec_GG; pfam07549
634456003546	protein-export membrane protein, SecD/SecF family; Region: 2A0604s01; TIGR00916
634456003547	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
634456003548	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
634456003549	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK09102
634456003550	Class I ribonucleotide reductase; Region: RNR_I; cd01679
634456003551	active site
634456003552	dimer interface [polypeptide binding]; other site
634456003553	catalytic residues [active]
634456003554	effector binding site; other site
634456003555	R2 peptide binding site; other site
634456003556	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
634456003557	dimer interface [polypeptide binding]; other site
634456003558	putative radical transfer pathway; other site
634456003559	diiron center [ion binding]; other site
634456003560	tyrosyl radical; other site
634456003561	Predicted O-methyltransferase [General function prediction only]; Region: COG4123
634456003562	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
634456003563	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
634456003564	substrate binding pocket [chemical binding]; other site
634456003565	chain length determination region; other site
634456003566	substrate-Mg2+ binding site; other site
634456003567	catalytic residues [active]
634456003568	aspartate-rich region 1; other site
634456003569	active site lid residues [active]
634456003570	aspartate-rich region 2; other site
634456003571	glutamate racemase; Provisional; Region: PRK00865
634456003572	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
634456003573	active site
634456003574	Escherichia coli (Ec) citrate synthase (CS) GltA_like. CS catalyzes the condensation of acetyl coenzyme A (AcCoA) and oxalacetate (OAA) to form citrate and coenzyme A (CoA), the first step in the citric acid cycle (TCA or Krebs cycle). The overall CS...; Region: EcCS_like; cd06114
634456003575	Citrate synthase [Energy production and conversion]; Region: GltA; COG0372
634456003576	dimer interface [polypeptide binding]; other site
634456003577	active site
634456003578	citrylCoA binding site [chemical binding]; other site
634456003579	NADH binding [chemical binding]; other site
634456003580	cationic pore residues; other site
634456003581	oxalacetate/citrate binding site [chemical binding]; other site
634456003582	coenzyme A binding site [chemical binding]; other site
634456003583	catalytic triad [active]
634456003584	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
634456003585	catalytic core [active]
634456003586	chorismate mutase; Provisional; Region: PRK09239
634456003587	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
634456003588	active site
634456003589	metal binding site [ion binding]; metal-binding site
634456003590	succinate CoA transferase; Region: YgfH_subfam; TIGR03458
634456003591	Acetyl-CoA hydrolase/transferase N-terminal domain; Region: AcetylCoA_hydro; pfam02550
634456003592	Acetyl-CoA hydrolase/transferase C-terminal domain; Region: AcetylCoA_hyd_C; pfam13336
634456003593	Catalytic domain of phosphoinositide-specific phospholipase C-like phosphodiesterases superfamily; Region: PI-PLCc_GDPD_SF; cl14615
634456003594	AAA domain; Region: AAA_23; pfam13476
634456003595	ATP-binding cassette domain of barmotin, a member of the SMC protein family; Region: ABC_SMC_barmotin; cd03278
634456003596	Walker A/P-loop; other site
634456003597	ATP binding site [chemical binding]; other site
634456003598	SMC proteins Flexible Hinge Domain; Region: SMC_hinge; cl05797
634456003599	ATP-binding cassette domain of barmotin, a member of the SMC protein family; Region: ABC_SMC_barmotin; cd03278
634456003600	ABC transporter signature motif; other site
634456003601	Walker B; other site
634456003602	D-loop; other site
634456003603	H-loop/switch region; other site
634456003604	Thioredoxin; Region: Thioredoxin_4; pfam13462
634456003605	Protein-disulfide isomerase [Posttranslational modification, protein turnover, chaperones]; Region: DsbG; COG1651
634456003606	Putative Mg2+ and Co2+ transporter CorC [Inorganic ion transport and metabolism]; Region: CorC; COG4535
634456003607	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
634456003608	Transporter associated domain; Region: CorC_HlyC; smart01091
634456003609	Uncharacterized protein family UPF0054; Region: UPF0054; pfam02130
634456003610	Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702
634456003611	PhoH-like protein; Region: PhoH; pfam02562
634456003612	(dimethylallyl)adenosine tRNA methylthiotransferase; Provisional; Region: PRK14325
634456003613	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
634456003614	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
634456003615	FeS/SAM binding site; other site
634456003616	TRAM domain; Region: TRAM; cl01282
634456003617	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
634456003618	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
634456003619	putative acyl-acceptor binding pocket; other site
634456003620	Outer membrane protein [Cell envelope biogenesis, outer membrane]; Region: COG0729
634456003621	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
634456003622	Surface antigen; Region: Bac_surface_Ag; pfam01103
634456003623	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2911
634456003624	Family of unknown function (DUF490); Region: DUF490; pfam04357
634456003625	Escherichia coli exonuclease III (ExoIII) and Neisseria meningitides NExo-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases; Region: ExoIII-like_AP-endo; cd09086
634456003626	putative catalytic site [active]
634456003627	putative phosphate binding site [ion binding]; other site
634456003628	active site
634456003629	metal binding site A [ion binding]; metal-binding site
634456003630	DNA binding site [nucleotide binding]
634456003631	putative AP binding site [nucleotide binding]; other site
634456003632	putative metal binding site B [ion binding]; other site
634456003633	Zn-dependent dipeptidase, microsomal dipeptidase homolog [Amino acid transport and metabolism]; Region: COG2355
634456003634	renal dipeptidase (rDP), best studied in mammals and also called membrane or microsomal dipeptidase, is a membrane-bound glycoprotein hydrolyzing dipeptides and is involved in hydrolytic metabolism of penem and carbapenem beta-lactam antibiotics; Region: rDP_like; cd01301
634456003635	active site
634456003636	dimer interface [polypeptide binding]; other site
634456003637	excinuclease ABC subunit C; Validated; Region: uvrC; PRK00558
634456003638	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
634456003639	GIY-YIG motif/motif A; other site
634456003640	active site
634456003641	catalytic site [active]
634456003642	putative DNA binding site [nucleotide binding]; other site
634456003643	metal binding site [ion binding]; metal-binding site
634456003644	UvrC Helix-hairpin-helix N-terminal; Region: UvrC_HhH_N; pfam08459
634456003645	CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; cl00453
634456003646	Ubiquitin domain of MoaD-like proteins; Region: MoaD; cd00754
634456003647	MoaE interaction surface [polypeptide binding]; other site
634456003648	MoeB interaction surface [polypeptide binding]; other site
634456003649	thiocarboxylated glycine; other site
634456003650	MoaE family. Members of this family are involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor for a diverse group of redox enzymes. Moco biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoaE; cd00756
634456003651	MoaE homodimer interface [polypeptide binding]; other site
634456003652	MoaD interaction [polypeptide binding]; other site
634456003653	active site residues [active]
634456003654	adenosylmethionine--8-amino-7-oxononanoate transaminase; Provisional; Region: PRK05964
634456003655	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
634456003656	inhibitor-cofactor binding pocket; inhibition site
634456003657	pyridoxal 5'-phosphate binding site [chemical binding]; other site
634456003658	catalytic residue [active]
634456003659	8-amino-7-oxononanoate synthase; Reviewed; Region: PRK05958
634456003660	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
634456003661	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
634456003662	catalytic residue [active]
634456003663	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
634456003664	biotin biosynthesis protein BioC; Region: BioC; TIGR02072
634456003665	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
634456003666	S-adenosylmethionine binding site [chemical binding]; other site
634456003667	AAA domain; Region: AAA_26; pfam13500
634456003668	dithiobiotin synthetase; Reviewed; Region: bioD; PRK00090
634456003669	LexA repressor; Validated; Region: PRK00215
634456003670	LexA DNA binding domain; Region: LexA_DNA_bind; pfam01726
634456003671	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
634456003672	Catalytic site [active]
634456003673	Molybdopterin biosynthesis enzyme [Coenzyme metabolism]; Region: MoeA; COG0303
634456003674	MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoeA; cd00887
634456003675	dimer interface [polypeptide binding]; other site
634456003676	putative functional site; other site
634456003677	putative MPT binding site; other site
634456003678	50S ribosomal protein L33; Validated; Region: rpmG; PRK00595
634456003679	Septum formation initiator; Region: DivIC; cl17659
634456003680	enolase; Provisional; Region: eno; PRK00077
634456003681	Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313
634456003682	dimer interface [polypeptide binding]; other site
634456003683	metal binding site [ion binding]; metal-binding site
634456003684	substrate binding pocket [chemical binding]; other site
634456003685	Protein of unknown function (DUF3429); Region: DUF3429; pfam11911
634456003686	glycine oxidase ThiO; Region: thiamin_ThiO; TIGR02352
634456003687	ThiaminS ubiquitin-like sulfur carrier protein; Region: ThiS; cd00565
634456003688	thiS-thiF/thiG interaction site; other site
634456003689	Thiazole synthase (ThiG) is the tetrameric enzyme that is involved in the formation of the thiazole moiety of thiamin pyrophosphate, an essential ubiquitous cofactor that plays an important role in carbohydrate and amino acid metabolism. ThiG catalyzes...; Region: ThiG; cd04728
634456003690	ThiS interaction site; other site
634456003691	putative active site [active]
634456003692	tetramer interface [polypeptide binding]; other site
634456003693	Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-; Region: TMP_TenI; cd00564
634456003694	thiamine phosphate binding site [chemical binding]; other site
634456003695	active site
634456003696	pyrophosphate binding site [ion binding]; other site
634456003697	ATP-dependent DNA helicase RecG; Provisional; Region: PRK10917
634456003698	RecG_wedge_OBF: A subfamily of OB folds corresponding to the OB fold found in the N-terminal (wedge) domain of Escherichia coli RecG. RecG is a branched-DNA-specific helicase, which catalyzes the interconversion of a DNA replication fork to a...; Region: RecG_wedge_OBF; cd04488
634456003699	generic binding surface II; other site
634456003700	ssDNA binding site; other site
634456003701	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
634456003702	ATP binding site [chemical binding]; other site
634456003703	putative Mg++ binding site [ion binding]; other site
634456003704	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
634456003705	nucleotide binding region [chemical binding]; other site
634456003706	ATP-binding site [chemical binding]; other site
634456003707	Flavinator of succinate dehydrogenase; Region: Sdh5; cl01110
634456003708	Transcription-repair coupling factor (superfamily II helicase) [DNA replication, recombination, and repair / Transcription]; Region: Mfd; COG1197
634456003709	CarD-like/TRCF domain; Region: CarD_TRCF; smart01058
634456003710	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
634456003711	ATP binding site [chemical binding]; other site
634456003712	putative Mg++ binding site [ion binding]; other site
634456003713	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
634456003714	nucleotide binding region [chemical binding]; other site
634456003715	ATP-binding site [chemical binding]; other site
634456003716	This domain is found in proteins necessary for strand-specific repair in DNA such as TRCF in Escherichia coli; Region: TRCF; smart00982
634456003717	Uncharacterized protein conserved in bacteria (DUF2125); Region: DUF2125; pfam09898
634456003718	Predicted Na+-dependent transporter [General function prediction only]; Region: COG0385
634456003719	SBF-like CPA transporter family (DUF4137); Region: DUF4137; pfam13593
634456003720	tyrosine decarboxylase; Region: PLN02880
634456003721	DOPA decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to DOPA/tyrosine decarboxylase (DDC), histidine decarboxylase (HDC), and...; Region: DOPA_deC_like; cd06450
634456003722	pyridoxal 5'-phosphate binding site [chemical binding]; other site
634456003723	catalytic residue [active]
634456003724	Cobalamin biosynthesis protein CobT; Region: CobT; pfam06213
634456003725	cobaltochelatase, CobT subunit; Region: CobT; TIGR01651
634456003726	norD type: Denitrifying bacteria contain both membrane bound and periplasmic nitrate reductases. Denitrification plays a major role  in completing the nitrogen cycle by converting nitrate or nitrite to nitrogen gas. The pathway for microbial...; Region: vWA_norD_type; cd01454
634456003727	metal ion-dependent adhesion site (MIDAS); other site
634456003728	Cobaltochelatase CobS subunit N terminal; Region: CobS_N; pfam12556
634456003729	cobaltochelatase, CobS subunit; Region: PD_CobS; TIGR01650
634456003730	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
634456003731	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
634456003732	HSP70 interaction site [polypeptide binding]; other site
634456003733	Stress-induced morphogen (activity unknown) [Signal transduction mechanisms]; Region: BolA; COG0271
634456003734	Outer membrane lipoprotein carrier protein LolA; Region: LolA; cl17548
634456003735	lipoate-protein ligase B; Provisional; Region: PRK14341
634456003736	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
634456003737	active site
634456003738	tetramer interface; other site
634456003739	The phosphomannomutase/phosphoglucomutase (PMM/PGM) bifunctional enzyme catalyzes the reversible conversion of 1-phospho to 6-phospho-sugars (e.g. between mannose-1-phosphate and mannose-6-phosphate or glucose-1-phosphate and glucose-6-phosphate) via a...; Region: PMM_PGM; cd03089
634456003740	active site
634456003741	Phosphomannomutase [Carbohydrate transport and metabolism]; Region: {ManB}; COG1109
634456003742	substrate binding site [chemical binding]; other site
634456003743	metal binding site [ion binding]; metal-binding site
634456003744	molybdenum cofactor biosynthesis protein A; Reviewed; Region: moaA; PRK00164
634456003745	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
634456003746	FeS/SAM binding site; other site
634456003747	Molybdenum Cofactor Synthesis C; Region: Mob_synth_C; pfam06463
634456003748	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
634456003749	S-adenosylmethionine binding site [chemical binding]; other site
634456003750	Predicted amidophosphoribosyltransferases [General function prediction only]; Region: ComFC; COG1040
634456003751	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
634456003752	active site
634456003753	Glutaredoxin (GRX) family, GRX bacterial class 1 and 3 (b_1_3)-like subfamily; composed of bacterial GRXs, approximately 10 kDa in size, and proteins containing a GRX or GRX-like domain. GRX is a glutathione (GSH) dependent reductase, catalyzing the...; Region: GRX_GRXb_1_3_like; cd03418
634456003754	GSH binding site [chemical binding]; other site
634456003755	catalytic residues [active]
634456003756	Protein of unknown function (DUF1178); Region: DUF1178; pfam06676
634456003757	Uncharacterized protein conserved in bacteria (DUF2147); Region: DUF2147; pfam09917
634456003758	Lactonase, 7-bladed beta-propeller; Region: Lactonase; pfam10282
634456003759	bifunctional 3-demethylubiquinone-9 3-methyltransferase/ 2-octaprenyl-6-hydroxy phenol methylase; Provisional; Region: PRK05134
634456003760	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
634456003761	S-adenosylmethionine binding site [chemical binding]; other site
634456003762	aspartate kinase; Reviewed; Region: PRK06635
634456003763	AAK_AKii-LysC-BS: Amino Acid Kinase Superfamily (AAK), AKii; this CD includes the N-terminal catalytic aspartokinase (AK) domain of the lysine-sensitive aspartokinase isoenzyme AKII of Bacillus subtilis 168, and the lysine plus threonine-sensitive...; Region: AAK_AKii-LysC-BS; cd04261
634456003764	putative nucleotide binding site [chemical binding]; other site
634456003765	putative catalytic residues [active]
634456003766	putative Mg ion binding site [ion binding]; other site
634456003767	putative aspartate binding site [chemical binding]; other site
634456003768	ACT domains of the lysine-sensitive aspartokinase isoenzyme AKII of Bacillus subtilis (BS) strain 168 and related proteins; Region: ACT_AKii-LysC-BS-like_1; cd04913
634456003769	putative allosteric regulatory site; other site
634456003770	ACT domains of the lysine-sensitive, aspartokinase (AK) isoenzyme AKII of Bacillus subtilis (BS) strain 168 and related domains; Region: ACT_AKii-LysC-BS-like_2; cd04936
634456003771	putative enoyl-[acyl-carrier-protein] reductase II; Region: enACPred_II; TIGR03151
634456003772	2-Nitropropane dioxygenase (NPD), one of the nitroalkane oxidizing enzyme families, catalyzes oxidative denitrification of nitroalkanes to their corresponding carbonyl compounds and nitrites. NDP is a member of the NAD(P)H-dependent flavin oxidoreductase...; Region: NPD_like; cd04730
634456003773	FMN binding site [chemical binding]; other site
634456003774	substrate binding site [chemical binding]; other site
634456003775	putative catalytic residue [active]
634456003776	Predicted transcriptional regulator contains Xre-like HTH domain [Function unknown]; Region: COG1426
634456003777	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
634456003778	non-specific DNA binding site [nucleotide binding]; other site
634456003779	salt bridge; other site
634456003780	sequence-specific DNA binding site [nucleotide binding]; other site
634456003781	Domain of unknown function (DUF4115); Region: DUF4115; pfam13464
634456003782	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Reviewed; Region: ispG; PRK00366
634456003783	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
634456003784	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
634456003785	histidyl-tRNA synthetase; Reviewed; Region: hisS; PRK00037
634456003786	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
634456003787	dimer interface [polypeptide binding]; other site
634456003788	motif 1; other site
634456003789	active site
634456003790	motif 2; other site
634456003791	motif 3; other site
634456003792	HisRS Histidyl-anticodon binding domain. HisRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: HisRS_anticodon; cd00859
634456003793	anticodon binding site; other site
634456003794	peptide chain release factor 1; Validated; Region: prfA; PRK00591
634456003795	PCRF domain; Region: PCRF; pfam03462
634456003796	RF-1 domain; Region: RF-1; pfam00472
634456003797	N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional; Region: PRK09328
634456003798	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
634456003799	Domain of unknown function (DUF4167); Region: DUF4167; pfam13763
634456003800	mce related protein; Region: MCE; pfam02470
634456003801	undecaprenyl pyrophosphate phosphatase; Reviewed; Region: PRK00281
634456003802	Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531
634456003803	ATP-grasp domain; Region: ATP-grasp_4; cl17255
634456003804	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
634456003805	Transglycosylase SLT domain; Region: SLT_2; pfam13406
634456003806	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
634456003807	N-acetyl-D-glucosamine binding site [chemical binding]; other site
634456003808	Lipoproteins [Cell envelope biogenesis, outer membrane]; Region: RlpA; COG0797
634456003809	Sporulation related domain; Region: SPOR; cl10051
634456003810	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
634456003811	D-alanyl-D-alanine carboxypeptidase [Cell envelope biogenesis, outer membrane]; Region: DacC; COG1686
634456003812	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; smart00936
634456003813	thymidylate kinase; Validated; Region: tmk; PRK00698
634456003814	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
634456003815	TMP-binding site; other site
634456003816	ATP-binding site [chemical binding]; other site
634456003817	DNA polymerase III subunit delta'; Validated; Region: PRK07471
634456003818	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
634456003819	Walker A motif; other site
634456003820	ATP binding site [chemical binding]; other site
634456003821	Walker B motif; other site
634456003822	arginine finger; other site
634456003823	methionyl-tRNA synthetase; Reviewed; Region: PRK11893
634456003824	catalytic core domain of methioninyl-tRNA synthetases; Region: MetRS_core; cd00814
634456003825	active site
634456003826	HIGH motif; other site
634456003827	KMSKS motif; other site
634456003828	Anticodon-binding domain of methionyl tRNA synthetases; Region: Anticodon_Ia_Met; cd07957
634456003829	tRNA binding surface [nucleotide binding]; other site
634456003830	anticodon binding site; other site
634456003831	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
634456003832	Predicted metal-dependent hydrolases with the TIM-barrel fold [General function prediction only]; Region: COG1099
634456003833	active site
634456003834	Metal-dependent hydrolases of the beta-lactamase superfamily I [General function prediction only]; Region: PhnP; COG1235
634456003835	putative hydrolase; Provisional; Region: PRK02113
634456003836	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
634456003837	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
634456003838	Ligand Binding Site [chemical binding]; other site
634456003839	pyridoxamine 5'-phosphate oxidase; Provisional; Region: PRK05679
634456003840	Pyridoxamine 5'-phosphate oxidase; Region: Pyridox_oxidase; pfam01243
634456003841	Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region; Region: PNPOx_C; pfam10590
634456003842	enoyl-(acyl carrier protein) reductase; Provisional; Region: PRK08159
634456003843	Enoyl acyl carrier protein (ACP) reductase (ENR), divergent SDR; Region: ENR_SDR; cd05372
634456003844	NAD binding site [chemical binding]; other site
634456003845	homotetramer interface [polypeptide binding]; other site
634456003846	homodimer interface [polypeptide binding]; other site
634456003847	substrate binding site [chemical binding]; other site
634456003848	active site
634456003849	Chorismate synthase [Amino acid transport and metabolism]; Region: AroC; COG0082
634456003850	Chorismase synthase, the enzyme catalyzing the final step of the shikimate pathway; Region: Chorismate_synthase; cd07304
634456003851	Tetramer interface [polypeptide binding]; other site
634456003852	active site
634456003853	FMN-binding site [chemical binding]; other site
634456003854	peroxiredoxin, OsmC subfamily; Region: osmo_induc_OsmC; TIGR03562
634456003855	malate:quinone oxidoreductase; Validated; Region: PRK05257
634456003856	malate:quinone-oxidoreductase; Region: mal_quin_oxido; TIGR01320
634456003857	6-pyruvoyl tetrahydropterin synthase; Region: PTPS; pfam01242
634456003858	ExsB is a transcription regulator related protein. It is a subfamily of a Adenosine nucleotide binding superfamily of proteins. This protein family is represented by a single member in nearly every completed large (> 1000 genes) prokaryotic genome. In...; Region: ExsB; cd01995
634456003859	Ligand Binding Site [chemical binding]; other site
634456003860	Organic radical activating enzymes [Posttranslational modification, protein turnover, chaperones]; Region: NrdG; COG0602
634456003861	putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE; Region: rSAM_QueE_Ecoli; TIGR04322
634456003862	biotin synthase; Region: bioB; TIGR00433
634456003863	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
634456003864	FeS/SAM binding site; other site
634456003865	Biotin and Thiamin Synthesis associated domain; Region: BATS; smart00876
634456003866	Putative hemolysin [General function prediction only]; Region: Hlx; COG3042
634456003867	Domain of unknown function (DUF333); Region: DUF333; pfam03891
634456003868	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes [Amino acid transport and metabolism / Coenzyme metabolism]; Region: CysH; COG0175
634456003869	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
634456003870	Active Sites [active]
634456003871	sulfate adenylyltransferase, small subunit; Region: CysD; TIGR02039
634456003872	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
634456003873	Active Sites [active]
634456003874	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
634456003875	bifunctional sulfate adenylyltransferase subunit 1/adenylylsulfate kinase protein; Provisional; Region: PRK05506
634456003876	G1 box; other site
634456003877	GTP/Mg2+ binding site [chemical binding]; other site
634456003878	G2 box; other site
634456003879	Switch I region; other site
634456003880	G3 box; other site
634456003881	Switch II region; other site
634456003882	G4 box; other site
634456003883	G5 box; other site
634456003884	Translation_Factor_II_like: Elongation factor Tu (EF-Tu) domain II-like proteins. Elongation factor Tu consists of three structural domains, this family represents the second domain. Domain II adopts a beta barrel structure and is involved in binding to...; Region: Translation_Factor_II_like; cl02787
634456003885	Domain III of Elongation factor (EF) Tu (EF-TU) and EF-G.  Elongation factors (EF) EF-Tu and EF-G participate in the elongation phase during protein biosynthesis on the ribosome. Their functional cycles depend on GTP binding and its hydrolysis. The EF-Tu...; Region: Translation_factor_III; cl02786
634456003886	Adenosine 5'-phosphosulfate kinase (APSK) catalyzes the phosphorylation of adenosine 5'-phosphosulfate to form 3'-phosphoadenosine 5'-phosphosulfate (PAPS). The end-product PAPS is a biologically "activated" sulfate form...; Region: APSK; cd02027
634456003887	ligand-binding site [chemical binding]; other site
634456003888	Protein of unknown function (DUF2849); Region: DUF2849; pfam11011
634456003889	Sulfite reductase, beta subunit (hemoprotein) [Inorganic ion transport and metabolism]; Region: CysI; COG0155
634456003890	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
634456003891	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
634456003892	Bacterial protein of unknown function (DUF934); Region: DUF934; pfam06073
634456003893	Lysophospholipid acyltransferases (LPLATs) of glycerophospholipid biosynthesis; Region: LPLAT; cl17185
634456003894	putative acyl-acceptor binding pocket; other site
634456003895	3-deoxy-D-manno-octulosonic-acid transferase; Reviewed; Region: PRK05749
634456003896	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase); Region: Glycos_transf_N; pfam04413
634456003897	tetraacyldisaccharide 4'-kinase; Reviewed; Region: lpxK; PRK00652
634456003898	tetraacyldisaccharide 4'-kinase; Region: lpxK; TIGR00682
634456003899	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
634456003900	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
634456003901	putative acyl-acceptor binding pocket; other site
634456003902	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
634456003903	FIG, FBPase/IMPase/glpX-like domain. A superfamily of metal-dependent phosphatases with various substrates. Fructose-1,6-bisphospatase (both the major and the glpX-encoded variant) hydrolyze fructose-1,6,-bisphosphate to fructose-6-phosphate in...; Region: FIG; cl00289
634456003904	active site
634456003905	The SYLF domain (also called DUF500), a novel lipid-binding module; Region: SYLF; cd11524
634456003906	putative amphipathic alpha helix; other site
634456003907	YceG-like family; Region: YceG; pfam02618
634456003908	proteins similar to Escherichia coli yceG; Region: yceG_like; cd08010
634456003909	dimerization interface [polypeptide binding]; other site
634456003910	3-oxoacyl-(acyl carrier protein) synthase II; Reviewed; Region: PRK07314
634456003911	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
634456003912	dimer interface [polypeptide binding]; other site
634456003913	active site
634456003914	acyl carrier protein; Provisional; Region: acpP; PRK00982
634456003915	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
634456003916	3-oxoacyl-(acyl-carrier-protein) reductase; Region: 3oxo_ACP_reduc; TIGR01830
634456003917	NAD(P) binding site [chemical binding]; other site
634456003918	active site
634456003919	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
634456003920	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
634456003921	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
634456003922	putative active site [active]
634456003923	Methyltransferase domain; Region: Methyltransf_31; pfam13847
634456003924	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
634456003925	S-adenosylmethionine binding site [chemical binding]; other site
634456003926	Substrate binding domain of ABC-type glycine betaine transport system; Region: OpuAC; pfam04069
634456003927	The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cl01709
634456003928	multiple promoter invertase; Provisional; Region: mpi; PRK13413
634456003929	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
634456003930	catalytic residues [active]
634456003931	catalytic nucleophile [active]
634456003932	Presynaptic Site I dimer interface [polypeptide binding]; other site
634456003933	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
634456003934	Synaptic Flat tetramer interface [polypeptide binding]; other site
634456003935	Synaptic Site I dimer interface [polypeptide binding]; other site
634456003936	DNA binding site [nucleotide binding]
634456003937	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
634456003938	DNA-binding interface [nucleotide binding]; DNA binding site
634456003939	Winged helix-turn helix; Region: HTH_29; pfam13551
634456003940	Helix-turn-helix domain; Region: HTH_28; pfam13518
634456003941	Homeodomain-like domain; Region: HTH_32; pfam13565
634456003942	Integrase core domain; Region: rve; pfam00665
634456003943	Integrase core domain; Region: rve_3; cl15866
634456003944	Mu transposase, C-terminal; Region: Mu-transpos_C; pfam09299
634456003945	Uncharacterized protein conserved in bacteria (DUF2219); Region: DUF2219; pfam09982
634456003946	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
634456003947	DNA-binding site [nucleotide binding]; DNA binding site
634456003948	RNA-binding motif; other site
634456003949	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
634456003950	DNA-binding site [nucleotide binding]; DNA binding site
634456003951	RNA-binding motif; other site
634456003952	Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294
634456003953	SmpB-tmRNA interface; other site
634456003954	Dihydrodipicolinate synthase/N-acetylneuraminate lyase [Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: DapA; COG0329
634456003955	Dihydrodipicolinate synthase (DHDPS); Region: DHDPS; cd00950
634456003956	dimer interface [polypeptide binding]; other site
634456003957	active site
634456003958	catalytic residue [active]
634456003959	prephenate dehydratase; Provisional; Region: PRK11899
634456003960	Prephenate dehydratase; Region: PDT; pfam00800
634456003961	C-terminal ACT domain of the bifunctional chorismate mutase-prephenate dehydratase (CM-PDT) enzyme and the prephenate dehydratase (PDT) enzyme; Region: ACT_CM-PDT; cd04905
634456003962	putative L-Phe binding site [chemical binding]; other site
634456003963	3-deoxy-manno-octulosonate cytidylyltransferase; Provisional; Region: PRK05450
634456003964	CMP-KDO synthetase catalyzes the activation of KDO which is an essential component of the lipopolysaccharide; Region: CMP-KDO-Synthetase; cd02517
634456003965	Ligand binding site; other site
634456003966	oligomer interface; other site
634456003967	Cytochrome c; Region: Cytochrom_C; cl11414
634456003968	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
634456003969	Predominantly bacterial family of Mg++ dependend phosphatases, related to inositol monophosphatases. These enzymes may dephosphorylate fructose-1,6-bisphosphate, inositol monophospate, 3'-phosphoadenosine-5'-phosphate,  or similar substrates; Region: Bacterial_IMPase_like_1; cd01641
634456003970	active site
634456003971	D-3-phosphoglycerate dehydrogenase; Provisional; Region: PRK11790
634456003972	Phosphoglycerate dehydrogenases, NAD-binding and catalytic domains; Region: PGDH_3; cd12176
634456003973	ligand binding site [chemical binding]; other site
634456003974	NAD binding site [chemical binding]; other site
634456003975	tetramer interface [polypeptide binding]; other site
634456003976	catalytic site [active]
634456003977	C-terminal ACT (regulatory) domain of D-3-Phosphoglycerate Dehydrogenase (3PGDH) found in fungi and bacteria; Region: ACT_3PGDH; cd04901
634456003978	L-serine binding site [chemical binding]; other site
634456003979	ACT domain interface; other site
634456003980	Predicted ATPase with chaperone activity [Posttranslational modification, protein turnover, chaperones]; Region: COG0606
634456003981	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
634456003982	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase; pfam01078
634456003983	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase_2; pfam13335
634456003984	cystathionine beta-lyase; Provisional; Region: PRK05967
634456003985	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
634456003986	homodimer interface [polypeptide binding]; other site
634456003987	substrate-cofactor binding pocket; other site
634456003988	pyridoxal 5'-phosphate binding site [chemical binding]; other site
634456003989	catalytic residue [active]
634456003990	Rhodanese-related sulfurtransferase [Inorganic ion transport and metabolism]; Region: SseA; COG2897
634456003991	Thiosulfate sulfurtransferase (TST), N-terminal, inactive domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the 1st repeat, which does not contain the catalytically active Cys residue. The role of the 1st repeat is uncertain, but it...; Region: TST_Repeat_1; cd01448
634456003992	active site residue [active]
634456003993	Thiosulfate sulfurtransferase (TST), C-terminal, catalytic domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the second repeat. Only the second repeat contains the catalytically active Cys residue; Region: TST_Repeat_2; cd01449
634456003994	active site residue [active]
634456003995	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
634456003996	Domain of unknown function DUF20; Region: UPF0118; pfam01594
634456003997	Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily; Region: EEP; cl00490
634456003998	putative catalytic site [active]
634456003999	putative metal binding site [ion binding]; other site
634456004000	putative phosphate binding site [ion binding]; other site
634456004001	cardiolipin synthetase; Reviewed; Region: cls; PRK01642
634456004002	Phospholipase_D-nuclease N-terminal; Region: PLDc_N; pfam13396
634456004003	Putative catalytic domain, repeat 1, of uncharacterized proteins similar to bacterial cardiolipin synthase; Region: PLDc_CLS_unchar2_1; cd09157
634456004004	putative active site [active]
634456004005	catalytic site [active]
634456004006	Putative catalytic domain, repeat 2, of uncharacterized proteins similar to bacterial cardiolipin synthase; Region: PLDc_CLS_unchar2_2; cd09163
634456004007	putative active site [active]
634456004008	catalytic site [active]
634456004009	hypothetical protein; Reviewed; Region: PRK12497
634456004010	Glutaredoxin (GRX) family, PKC-interacting cousin of TRX (PICOT)-like subfamily; composed of PICOT and GRX-PICOT-like proteins. The non-PICOT members of this family contain only the GRX-like domain, whereas PICOT contains an N-terminal TRX-like domain...; Region: GRX_PICOT_like; cd03028
634456004011	putative GSH binding site [chemical binding]; other site
634456004012	catalytic residues [active]
634456004013	Stress-induced morphogen (activity unknown) [Signal transduction mechanisms]; Region: BolA; COG0271
634456004014	phosphoribosylformylglycinamidine synthase II; Provisional; Region: PRK01213
634456004015	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), first repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat1; cd02203
634456004016	dimerization interface [polypeptide binding]; other site
634456004017	ATP binding site [chemical binding]; other site
634456004018	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), second repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat2; cd02204
634456004019	dimerization interface [polypeptide binding]; other site
634456004020	ATP binding site [chemical binding]; other site
634456004021	phosphoribosylformylglycinamidine synthase I; Provisional; Region: PRK03619
634456004022	Type 1 glutamine amidotransferase (GATase1)-like domain found in Formylglycinamide ribonucleotide amidotransferase; Region: GATase1_FGAR_AT; cd01740
634456004023	putative active site [active]
634456004024	catalytic triad [active]
634456004025	Phosphoribosylformylglycinamidine (FGAM) synthase; Region: PurS; pfam02700
634456004026	phosphoribosylaminoimidazole-succinocarboxamide synthase; Reviewed; Region: PRK09362
634456004027	bacterial and archaeal 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; Region: SAICAR_synt_PurC; cd01415
634456004028	ATP binding site [chemical binding]; other site
634456004029	active site
634456004030	substrate binding site [chemical binding]; other site
634456004031	adenylosuccinate lyase; Provisional; Region: PRK07492
634456004032	Adenylsuccinate lyase (ASL)_subgroup 1; Region: Adenylsuccinate_lyase_1; cd01360
634456004033	tetramer interface [polypeptide binding]; other site
634456004034	active site
634456004035	Adenylosuccinate lyase C-terminus; Region: ADSL_C; smart00998
634456004036	integral membrane protein, YjbE family; Region: R_switched_YjbE; TIGR03717
634456004037	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
634456004038	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
634456004039	N-acetyl-D-glucosamine binding site [chemical binding]; other site
634456004040	catalytic residue [active]
634456004041	Phosphatidylglycerophosphatase A; a bacterial membrane-associated enzyme involved in lipid metabolism; Region: PgpA; cd06971
634456004042	tetramer interfaces [polypeptide binding]; other site
634456004043	binuclear metal-binding site [ion binding]; other site
634456004044	Competence-damaged protein; Region: CinA; pfam02464
634456004045	Coenzyme Q-binding protein COQ10p and similar proteins; Region: COQ10p_like; cd07813
634456004046	putative coenzyme Q binding site [chemical binding]; other site
634456004047	lipoyl synthase; Provisional; Region: PRK05481
634456004048	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
634456004049	FeS/SAM binding site; other site
634456004050	dihydrolipoamide dehydrogenase; Reviewed; Region: PRK06416
634456004051	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
634456004052	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
634456004053	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
634456004054	pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase, long form; Region: PDHac_trf_mito; TIGR01349
634456004055	E3 interaction surface; other site
634456004056	lipoyl attachment site [posttranslational modification]; other site
634456004057	e3 binding domain; Region: E3_binding; pfam02817
634456004058	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
634456004059	pyruvate dehydrogenase subunit beta; Provisional; Region: PRK11892
634456004060	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
634456004061	E3 interaction surface; other site
634456004062	lipoyl attachment site [posttranslational modification]; other site
634456004063	Pyrimidine (PYR) binding domain of the beta subunits of the E1 components of human pyruvate dehydrogenase complex (E1- PDHc) and related proteins; Region: TPP_PYR_E1-PDHc-beta_like; cd07036
634456004064	alpha subunit interface [polypeptide binding]; other site
634456004065	TPP binding site [chemical binding]; other site
634456004066	heterodimer interface [polypeptide binding]; other site
634456004067	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
634456004068	pyruvate dehydrogenase E1 component, alpha subunit; Region: PDH_E1_alph_y; TIGR03182
634456004069	Thiamine pyrophosphate (TPP) family, E1 of PDC_ADC_BCADC subfamily, TPP-binding module; composed of proteins similar to the E1 components of the human pyruvate dehydrogenase complex (PDC), the acetoin dehydrogenase complex (ADC) and the branched chain...; Region: TPP_E1_PDC_ADC_BCADC; cd02000
634456004070	tetramer interface [polypeptide binding]; other site
634456004071	TPP-binding site [chemical binding]; other site
634456004072	heterodimer interface [polypeptide binding]; other site
634456004073	phosphorylation loop region [posttranslational modification]
634456004074	molybdenum cofactor biosynthesis protein MoaC; Provisional; Region: moaC; PRK09364
634456004075	trimer interface [polypeptide binding]; other site
634456004076	dimer interface [polypeptide binding]; other site
634456004077	putative active site [active]
634456004078	Indole-3-glycerol phosphate synthase (IGPS); an enzyme in the tryptophan biosynthetic pathway, catalyzing the ring closure reaction of 1-(o-carboxyphenylamino)-1-deoxyribulose-5-phosphate (CdRP) to indole-3-glycerol phosphate (IGP), accompanied by the...; Region: IGPS; cd00331
634456004079	active site
634456004080	ribulose/triose binding site [chemical binding]; other site
634456004081	phosphate binding site [ion binding]; other site
634456004082	substrate (anthranilate) binding pocket [chemical binding]; other site
634456004083	product (indole) binding pocket [chemical binding]; other site
634456004084	anthranilate phosphoribosyltransferase; Provisional; Region: trpD; PRK00188
634456004085	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
634456004086	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
634456004087	para-aminobenzoate synthase component II; Provisional; Region: PRK08857
634456004088	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
634456004089	glutamine binding [chemical binding]; other site
634456004090	catalytic triad [active]
634456004091	anthranilate synthase component I; Provisional; Region: PRK13573
634456004092	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
634456004093	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
634456004094	SurA N-terminal domain; Region: SurA_N_3; cl07813
634456004095	Parvulin-like peptidyl-prolyl isomerase [Posttranslational modification, protein turnover, chaperones]; Region: SurA; COG0760
634456004096	PPIC-type PPIASE domain; Region: Rotamase_2; pfam13145
634456004097	triosephosphate isomerase; Provisional; Region: PRK14565
634456004098	Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311
634456004099	substrate binding site [chemical binding]; other site
634456004100	dimer interface [polypeptide binding]; other site
634456004101	catalytic triad [active]
634456004102	Preprotein translocase subunit SecG [Intracellular trafficking and secretion]; Region: SecG; COG1314
634456004103	CTP synthetase; Validated; Region: pyrG; PRK05380
634456004104	CTP synthetase (CTPs) is a two-domain protein, which consists of an N-terminal synthetase domain and C-terminal glutaminase domain. The enzymes hydrolyze the amide bond of glutamine to ammonia and glutamate at the glutaminase domains and transfer nascent...; Region: CTGs; cd03113
634456004105	Catalytic site [active]
634456004106	active site
634456004107	UTP binding site [chemical binding]; other site
634456004108	Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; Region: GATase1_CTP_Synthase; cd01746
634456004109	active site
634456004110	putative oxyanion hole; other site
634456004111	catalytic triad [active]
634456004112	2-dehydro-3-deoxyphosphooctonate aldolase; Provisional; Region: PRK05198
634456004113	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
634456004114	DNA gyrase subunit B; Provisional; Region: gyrB; PRK14939
634456004115	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
634456004116	ATP binding site [chemical binding]; other site
634456004117	Mg2+ binding site [ion binding]; other site
634456004118	G-X-G motif; other site
634456004119	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
634456004120	anchoring element; other site
634456004121	dimer interface [polypeptide binding]; other site
634456004122	ATP binding site [chemical binding]; other site
634456004123	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
634456004124	active site
634456004125	putative metal-binding site [ion binding]; other site
634456004126	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
634456004127	recombination protein F; Reviewed; Region: recF; PRK00064
634456004128	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
634456004129	Walker A/P-loop; other site
634456004130	ATP binding site [chemical binding]; other site
634456004131	Q-loop/lid; other site
634456004132	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
634456004133	ABC transporter signature motif; other site
634456004134	Walker B; other site
634456004135	D-loop; other site
634456004136	H-loop/switch region; other site
634456004137	DNA polymerase III subunit beta; Validated; Region: PRK05643
634456004138	Beta clamp domain.  The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria.  The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cd00140
634456004139	putative DNA binding surface [nucleotide binding]; other site
634456004140	dimer interface [polypeptide binding]; other site
634456004141	beta-clamp/clamp loader binding surface; other site
634456004142	beta-clamp/translesion DNA polymerase binding surface; other site
634456004143	DnaA N-terminal domain; Region: DnaA_N; pfam11638
634456004144	chromosomal replication initiator protein DnaA; Region: DnaA; TIGR00362
634456004145	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
634456004146	Walker A motif; other site
634456004147	ATP binding site [chemical binding]; other site
634456004148	Walker B motif; other site
634456004149	arginine finger; other site
634456004150	C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571
634456004151	DnaA box-binding interface [nucleotide binding]; other site
634456004152	30S ribosomal protein S20; Reviewed; Region: rpsT; PRK00239
634456004153	formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA glycosylase; Validated; Region: PRK01103
634456004154	N-terminal domain of Escherichia coli Fpg1/MutM and related bacterial DNA glycosylases; Region: EcFpg-like_N; cd08966
634456004155	DNA binding site [nucleotide binding]
634456004156	catalytic residue [active]
634456004157	H2TH interface [polypeptide binding]; other site
634456004158	putative catalytic residues [active]
634456004159	turnover-facilitating residue; other site
634456004160	intercalation triad [nucleotide binding]; other site
634456004161	8OG recognition residue [nucleotide binding]; other site
634456004162	putative reading head residues; other site
634456004163	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
634456004164	Methylase involved in ubiquinone/menaquinone biosynthesis [Coenzyme metabolism]; Region: UbiE; COG2226
634456004165	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
634456004166	S-adenosylmethionine binding site [chemical binding]; other site
634456004167	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated; Region: PRK05579
634456004168	Flavoprotein; Region: Flavoprotein; pfam02441
634456004169	DNA / pantothenate metabolism flavoprotein; Region: DFP; pfam04127
634456004170	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
634456004171	trimer interface [polypeptide binding]; other site
634456004172	active site
634456004173	ABC-type anion transport system, duplicated permease component [Inorganic ion transport and metabolism]; Region: COG4986
634456004174	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
634456004175	dimer interface [polypeptide binding]; other site
634456004176	conserved gate region; other site
634456004177	putative PBP binding loops; other site
634456004178	ABC-ATPase subunit interface; other site
634456004179	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: TauB; COG1116
634456004180	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
634456004181	Walker A/P-loop; other site
634456004182	ATP binding site [chemical binding]; other site
634456004183	Q-loop/lid; other site
634456004184	ABC transporter signature motif; other site
634456004185	Walker B; other site
634456004186	D-loop; other site
634456004187	H-loop/switch region; other site
634456004188	ABC nitrate/sulfonate/bicarbonate family transporter, ATPase subunit; Region: ABC_transp; pfam09821
634456004189	methionine sulfoxide reductase A; Provisional; Region: PRK14054
634456004190	valyl-tRNA synthetase; Reviewed; Region: valS; PRK05729
634456004191	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
634456004192	HIGH motif; other site
634456004193	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
634456004194	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
634456004195	active site
634456004196	KMSKS motif; other site
634456004197	Anticodon-binding domain of valyl tRNA synthetases; Region: Anticodon_Ia_Val; cd07962
634456004198	tRNA binding surface [nucleotide binding]; other site
634456004199	anticodon binding site; other site
634456004200	Valyl tRNA synthetase tRNA binding arm; Region: Val_tRNA-synt_C; pfam10458
634456004201	Protein of unknown function (DUF2497); Region: DUF2497; pfam10691
634456004202	type I secretion outer membrane protein, TolC family; Region: type_I_sec_TolC; TIGR01844
634456004203	Protein-L-isoaspartate carboxylmethyltransferase [Posttranslational modification, protein turnover, chaperones]; Region: Pcm; COG2518
634456004204	Hint domain; Region: Hint_2; pfam13403
634456004205	Short-chain dehydrogenases of various substrate specificities [General function prediction only]; Region: DltE; COG0300
634456004206	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
634456004207	NAD(P) binding site [chemical binding]; other site
634456004208	active site
634456004209	thiamine monophosphate kinase; Provisional; Region: PRK05731
634456004210	ThiL (Thiamine-monophosphate kinase) plays a dual role in de novo biosynthesis and in salvage of exogenous thiamine. Thiamine salvage occurs in two steps, with thiamine kinase catalyzing the formation of thiamine phosphate, and ThiL catalyzing the...; Region: ThiL; cd02194
634456004211	ATP binding site [chemical binding]; other site
634456004212	dimerization interface [polypeptide binding]; other site
634456004213	transcription antitermination factor NusB; Region: nusB; TIGR01951
634456004214	putative RNA binding site [nucleotide binding]; other site
634456004215	transcriptional regulator NrdR; Validated; Region: nrdR; PRK00464
634456004216	ATP cone domain; Region: ATP-cone; pfam03477
634456004217	Protein of unknown function (DUF461); Region: DUF461; pfam04314
634456004218	Glycerol kinase [Energy production and conversion]; Region: GlpK; COG0554
634456004219	Escherichia coli glycerol kinase-like proteins; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_EcGK_like; cd07786
634456004220	N- and C-terminal domain interface [polypeptide binding]; other site
634456004221	active site
634456004222	MgATP binding site [chemical binding]; other site
634456004223	catalytic site [active]
634456004224	metal binding site [ion binding]; metal-binding site
634456004225	glycerol binding site [chemical binding]; other site
634456004226	homotetramer interface [polypeptide binding]; other site
634456004227	homodimer interface [polypeptide binding]; other site
634456004228	FBP binding site [chemical binding]; other site
634456004229	protein IIAGlc interface [polypeptide binding]; other site
634456004230	Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; Region: MIP; cd00333
634456004231	amphipathic channel; other site
634456004232	Asn-Pro-Ala signature motifs; other site
634456004233	glycerol-3-phosphate dehydrogenase; Reviewed; Region: glpD; PRK12266
634456004234	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
634456004235	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
634456004236	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
634456004237	ATP-dependent DNA helicase RecQ; Region: recQ; TIGR01389
634456004238	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
634456004239	ATP binding site [chemical binding]; other site
634456004240	putative Mg++ binding site [ion binding]; other site
634456004241	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
634456004242	nucleotide binding region [chemical binding]; other site
634456004243	ATP-binding site [chemical binding]; other site
634456004244	This DNA-binding domain is found in the RecQ helicase among others and has a helix-turn-helix structure; Region: RQC; smart00956
634456004245	HRDC domain; Region: HRDC; pfam00570
634456004246	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
634456004247	ligand binding site [chemical binding]; other site
634456004248	thiol reductant ABC exporter, CydD subunit; Region: CydD; TIGR02857
634456004249	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
634456004250	Walker A/P-loop; other site
634456004251	ATP binding site [chemical binding]; other site
634456004252	Q-loop/lid; other site
634456004253	ABC transporter signature motif; other site
634456004254	Walker B; other site
634456004255	D-loop; other site
634456004256	H-loop/switch region; other site
634456004257	thiol reductant ABC exporter, CydD subunit; Region: CydD; TIGR02857
634456004258	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
634456004259	Walker A/P-loop; other site
634456004260	ATP binding site [chemical binding]; other site
634456004261	Q-loop/lid; other site
634456004262	ABC transporter signature motif; other site
634456004263	Walker B; other site
634456004264	D-loop; other site
634456004265	H-loop/switch region; other site
634456004266	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG3920
634456004267	Histidine kinase; Region: HisKA_2; pfam07568
634456004268	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
634456004269	ATP binding site [chemical binding]; other site
634456004270	Mg2+ binding site [ion binding]; other site
634456004271	G-X-G motif; other site
634456004272	RNA polymerase sigma factor; Provisional; Region: PRK12547
634456004273	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
634456004274	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
634456004275	DNA binding residues [nucleotide binding]
634456004276	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
634456004277	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
634456004278	DNA binding residues [nucleotide binding]
634456004279	two-component response regulator; Provisional; Region: PRK09191
634456004280	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
634456004281	active site
634456004282	phosphorylation site [posttranslational modification]
634456004283	intermolecular recognition site; other site
634456004284	dimerization interface [polypeptide binding]; other site
634456004285	ABC transporter ATPase component; Reviewed; Region: PRK11147
634456004286	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
634456004287	ABC transporter; Region: ABC_tran_2; pfam12848
634456004288	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
634456004289	trehalase; Provisional; Region: treF; PRK13270
634456004290	Trehalase; Region: Trehalase; cl17346
634456004291	class III alcohol dehydrogenases; Region: alcohol_DH_class_III; cd08300
634456004292	S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; Region: adh_III_F_hyde; TIGR02818
634456004293	substrate binding site [chemical binding]; other site
634456004294	catalytic Zn binding site [ion binding]; other site
634456004295	NAD binding site [chemical binding]; other site
634456004296	structural Zn binding site [ion binding]; other site
634456004297	dimer interface [polypeptide binding]; other site
634456004298	Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism [Inorganic ion transport and metabolism]; Region: PhnA; COG2824
634456004299	PhnA Zinc-Ribbon; Region: PhnA_Zn_Ribbon; pfam08274
634456004300	PhnA protein; Region: PhnA; pfam03831
634456004301	threonine/serine transporter TdcC; Provisional; Region: PRK13629; cl17672
634456004302	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
634456004303	2-dehydropantoate 2-reductase; Reviewed; Region: PRK06522
634456004304	Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558
634456004305	Ketopantoate reductase PanE/ApbA C terminal; Region: ApbA_C; pfam08546
634456004306	Predicted epimerase, PhzC/PhzF homolog [General function prediction only]; Region: COG0384
634456004307	hydroxyproline-2-epimerase; Provisional; Region: PRK13971
634456004308	amidohydrolase; Provisional; Region: PRK12393
634456004309	TRZ/ATZ family contains enzymes from the atrazine degradation pathway and related hydrolases. Atrazine, a chlorinated herbizide, can be catabolized by a variety of different bacteria. The first three steps of the atrazine dehalogenation pathway are...; Region: ATZ_TRZ_like; cd01298
634456004310	active site
634456004311	putative substrate binding pocket [chemical binding]; other site
634456004312	NMT1/THI5 like; Region: NMT1; pfam09084
634456004313	Predicted small integral membrane protein (DUF2165); Region: DUF2165; pfam09933
634456004314	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: TauB; COG1116
634456004315	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
634456004316	Walker A/P-loop; other site
634456004317	ATP binding site [chemical binding]; other site
634456004318	Q-loop/lid; other site
634456004319	ABC transporter signature motif; other site
634456004320	Walker B; other site
634456004321	D-loop; other site
634456004322	H-loop/switch region; other site
634456004323	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
634456004324	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
634456004325	dimer interface [polypeptide binding]; other site
634456004326	ABC-ATPase subunit interface; other site
634456004327	putative PBP binding loops; other site
634456004328	Isopenicillin N synthase and related dioxygenases [General function prediction only]; Region: PcbC; COG3491
634456004329	non-haem dioxygenase in morphine synthesis N-terminal; Region: DIOX_N; pfam14226
634456004330	2OG-Fe(II) oxygenase superfamily; Region: 2OG-FeII_Oxy; pfam03171
634456004331	hydroxydechloroatrazine ethylaminohydrolase; Reviewed; Region: PRK08203
634456004332	TRZ/ATZ family contains enzymes from the atrazine degradation pathway and related hydrolases. Atrazine, a chlorinated herbizide, can be catabolized by a variety of different bacteria. The first three steps of the atrazine dehalogenation pathway are...; Region: ATZ_TRZ_like; cd01298
634456004333	active site
634456004334	putative substrate binding pocket [chemical binding]; other site
634456004335	TonB-dependent siderophore receptor; Region: TonB-siderophor; TIGR01783
634456004336	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
634456004337	allantoate amidohydrolase; Reviewed; Region: PRK09290
634456004338	M20 Peptidase beta-alanine synthase, an amidohydrolase; Region: M20_bAS; cd03884
634456004339	active site
634456004340	metal binding site [ion binding]; metal-binding site
634456004341	dimer interface [polypeptide binding]; other site
634456004342	Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase [Amino acid transport and metabolism]; Region: COG0075
634456004343	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
634456004344	catalytic residue [active]
634456004345	Protein of unknown function (DUF3225); Region: DUF3225; pfam11533
634456004346	SnoaL-like domain; Region: SnoaL_3; pfam13474
634456004347	Protein of unknown function (DUF4089); Region: DUF4089; pfam13318
634456004348	amidase; Provisional; Region: PRK09201
634456004349	Amidase; Region: Amidase; pfam01425
634456004350	XdhC and CoxI family; Region: XdhC_CoxI; pfam02625
634456004351	xanthine dehydrogenase accessory protein XdhC; Region: xanthine_xdhC; TIGR02964
634456004352	XdhC Rossmann domain; Region: XdhC_C; pfam13478
634456004353	xanthine dehydrogenase, molybdopterin binding subunit; Region: xanthine_xdhB; TIGR02965
634456004354	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Region: Ald_Xan_dh_C; smart01008
634456004355	Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738
634456004356	xanthine dehydrogenase, small subunit; Region: xanthine_xdhA; TIGR02963
634456004357	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
634456004358	catalytic loop [active]
634456004359	iron binding site [ion binding]; other site
634456004360	[2Fe-2S] binding domain; Region: Fer2_2; pfam01799
634456004361	CO dehydrogenase flavoprotein C-terminal domain; Region: CO_deh_flav_C; pfam03450
634456004362	xanthine permease; Region: pbuX; TIGR03173
634456004363	HIUase (5-hydroxyisourate hydrolase) catalyzes the second step in a three-step ureide pathway in which 5-hydroxyisourate (HIU), a product of the uricase (urate oxidase) reaction, is hydrolyzed to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU); Region: TLP_HIUase; cd05822
634456004364	active site
634456004365	homotetramer interface [polypeptide binding]; other site
634456004366	OHCU decarboxylase; Region: OHCU_decarbox; pfam09349
634456004367	putative urate catabolism protein; Region: uraD_N-term-dom; TIGR03212
634456004368	Catalytic domain of bacterial PuuE allantoinases, Schizosaccharomyces pombe chitin deacetylase 1 (SpCDA1), and similar proteins; Region: CE4_PuuE_SpCDA1; cd10977
634456004369	active site
634456004370	catalytic site [active]
634456004371	tetramer interface [polypeptide binding]; other site
634456004372	Predicted flavoprotein involved in K+ transport [Inorganic ion transport and metabolism]; Region: TrkA; COG2072
634456004373	FAD-NAD(P)-binding; Region: NAD_binding_9; pfam13454
634456004374	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
634456004375	Transcriptional regulator [Transcription]; Region: LysR; COG0583
634456004376	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
634456004377	dimerization interface [polypeptide binding]; other site
634456004378	guanine deaminase; Provisional; Region: PRK09228
634456004379	Guanine deaminase (GDEase). Guanine deaminase is an aminohydrolase responsible for the conversion of guanine to xanthine and ammonia, the first step to utilize guanine as a nitrogen source. This reaction also removes the guanine base from the pool and...; Region: GDEase; cd01303
634456004380	active site
634456004381	Gamma-glutamyltransferase [Amino acid transport and metabolism]; Region: Ggt; COG0405
634456004382	Gamma-glutamyltranspeptidase; Region: G_glu_transpept; pfam01019
634456004383	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
634456004384	Biopolymer transport protein ExbD/TolR; Region: ExbD; pfam02472
634456004385	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
634456004386	Biopolymer transport protein ExbD/TolR; Region: ExbD; pfam02472
634456004387	Biopolymer transport proteins [Intracellular trafficking and secretion]; Region: TolQ; COG0811
634456004388	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
634456004389	putative efflux pump membrane fusion protein; Provisional; Region: PRK03598
634456004390	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
634456004391	HlyD family secretion protein; Region: HlyD_3; pfam13437
634456004392	ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only]; Region: COG1123
634456004393	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
634456004394	Walker A/P-loop; other site
634456004395	ATP binding site [chemical binding]; other site
634456004396	Q-loop/lid; other site
634456004397	ABC transporter signature motif; other site
634456004398	Walker B; other site
634456004399	D-loop; other site
634456004400	H-loop/switch region; other site
634456004401	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
634456004402	Walker A/P-loop; other site
634456004403	ATP binding site [chemical binding]; other site
634456004404	Q-loop/lid; other site
634456004405	ABC transporter signature motif; other site
634456004406	Walker B; other site
634456004407	D-loop; other site
634456004408	H-loop/switch region; other site
634456004409	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
634456004410	ABC-2 family transporter protein; Region: ABC2_membrane_2; pfam12679
634456004411	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
634456004412	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
634456004413	Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: TolC; COG1538
634456004414	Transcriptional regulator [Transcription]; Region: LysR; COG0583
634456004415	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
634456004416	C-terminal substrate binding domain of LysR-type transcriptional regulator CysL, which activates the transcription of the cysJI operon encoding sulfite reductase, contains the type 2 periplasmic binding fold; Region: PBP2_CysL_like; cd08420
634456004417	putative dimerization interface [polypeptide binding]; other site
634456004418	Predicted membrane protein [Function unknown]; Region: COG2855
634456004419	squalene-hopene cyclase; Region: hopene_cyclase; TIGR01507
634456004420	Squalene cyclase (SQCY) domain subgroup 1; found in class II terpene cyclases that have an alpha 6 - alpha 6 barrel fold. Squalene cyclase (SQCY)  and 2,3-oxidosqualene cyclase (OSQCY) are integral membrane proteins that catalyze a cationic cyclization...; Region: SQCY_1; cd02892
634456004421	Active site cavity [active]
634456004422	catalytic acid [active]
634456004423	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
634456004424	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
634456004425	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
634456004426	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
634456004427	WHG domain; Region: WHG; pfam13305
634456004428	Secretory lipase; Region: LIP; pfam03583
634456004429	Na+/H+ antiporter 1; Region: Na_H_antiport_1; cl01133
634456004430	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
634456004431	Mycobacterium tuberculosis succinate-semialdehyde dehydrogenase 1-like; Region: ALDH_SSADH1_GabD1; cd07100
634456004432	NAD(P) binding site [chemical binding]; other site
634456004433	catalytic residues [active]
634456004434	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
634456004435	Old yellow enzyme (OYE)-like FMN binding domain. OYE was the first flavin-dependent enzyme identified, however its true physiological role remains elusive to this day. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a...; Region: OYE_like_FMN; cd02933
634456004436	FMN binding site [chemical binding]; other site
634456004437	active site
634456004438	substrate binding site [chemical binding]; other site
634456004439	catalytic residue [active]
634456004440	Predicted transcriptional regulators [Transcription]; Region: COG1733
634456004441	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
634456004442	hydroperoxidase II; Provisional; Region: katE; PRK11249
634456004443	Catalase-like heme-binding proteins and protein domains; Region: catalase_like; cl09506
634456004444	heme binding pocket [chemical binding]; other site
634456004445	Type 1 glutamine amidotransferase (GATase1)-like domain found in at the C-terminal of several large catalases; Region: GATase1_catalase; cd03132
634456004446	domain interactions; other site
634456004447	Protein chain release factor B [Translation, ribosomal structure and biogenesis]; Region: PrfB; COG1186
634456004448	hypothetical protein; Provisional; Region: PRK09256
634456004449	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
634456004450	Putative glucoamylase; Region: Glycoamylase; pfam10091
634456004451	Putative glucoamylase; Region: Glycoamylase; pfam10091
634456004452	Second GH94N domain of cyclic beta 1-2 glucan synthetase and similar domains; Region: GH94N_ChvB_NdvB_2_like; cd11753
634456004453	Cellobiose phosphorylase [Carbohydrate transport and metabolism]; Region: COG3459
634456004454	First GH94N domain of cyclic beta 1-2 glucan synthetase and similar domains; Region: GH94N_ChvB_NdvB_1_like; cd11756
634456004455	Imidazolonepropionase and related amidohydrolases [Secondary metabolites biosynthesis, transport, and catabolism]; Region: HutI; COG1228
634456004456	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
634456004457	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
634456004458	active site
634456004459	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
634456004460	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
634456004461	Coenzyme A binding pocket [chemical binding]; other site
634456004462	4-amino-5-hydroxymethyl-2-methyl-pyrimidine phosphate kinase (HMPP-kinase) catalyzes two consecutive phosphorylation steps in the thiamine phosphate biosynthesis pathway, leading to the synthesis of vitamin B1. The first step is the phosphorylation of...; Region: HMPP_kinase; cd01169
634456004463	dimer interface [polypeptide binding]; other site
634456004464	substrate binding site [chemical binding]; other site
634456004465	ATP binding site [chemical binding]; other site
634456004466	P-loop containing Nucleoside Triphosphate Hydrolases; Region: P-loop_NTPase; cl09099
634456004467	ABC transporter signature motif; other site
634456004468	Walker B; other site
634456004469	D-loop; other site
634456004470	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
634456004471	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
634456004472	ABC-type uncharacterized transport system, permease and ATPase components [General function prediction only]; Region: COG4178
634456004473	ABC transporter transmembrane region 2; Region: ABC_membrane_2; cl00549
634456004474	ATP-binding cassette domain of peroxisomal transporter, subfamily D; Region: ABCD_peroxisomal_ALDP; cd03223
634456004475	Protein of unknown function DUF72; Region: DUF72; pfam01904
634456004476	Uncharacterized conserved protein [Function unknown]; Region: COG2135
634456004477	Escherichia coli YegD, a putative chaperone protein, and related proteins; Region: YegD_like; cd10231
634456004478	putative chaperone; Provisional; Region: PRK11678
634456004479	nucleotide binding site [chemical binding]; other site
634456004480	putative NEF/HSP70 interaction site [polypeptide binding]; other site
634456004481	SBD interface [polypeptide binding]; other site
634456004482	Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: TolC; COG1538
634456004483	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
634456004484	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
634456004485	HlyD family secretion protein; Region: HlyD_3; pfam13437
634456004486	Membrane transporters of cations and cationic drugs [Inorganic ion transport and metabolism]; Region: EmrE; COG2076
634456004487	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
634456004488	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
634456004489	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4320
634456004490	Uncharacterized protein conserved in bacteria (DUF2252); Region: DUF2252; pfam10009
634456004491	Uncharacterized protein involved in outer membrane biogenesis [Cell envelope biogenesis, outer membrane]; Region: AsmA; COG2982
634456004492	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
634456004493	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
634456004494	putative substrate translocation pore; other site
634456004495	Predicted metal-dependent hydrolase of the TIM-barrel fold [General function prediction only]; Region: COG3618
634456004496	2-pyrone-4,6-dicarboxylic acid (PDC) hydrolase hydrolyzes PDC to yield 4-oxalomesaconic acid (OMA) or its tautomer, 4-carboxy-2-hydroxymuconic acid (CHM). This reaction is part of the protocatechuate (PCA) 4,5-cleavage pathway. PCA is one of the most...; Region: PDC_hydrolase; cd01311
634456004497	active site
634456004498	hypothetical protein; Provisional; Region: PRK09945
634456004499	Hint domain; Region: Hint_2; pfam13403
634456004500	SnoaL-like domain; Region: SnoaL_2; pfam12680
634456004501	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
634456004502	Helix-turn-helix domain; Region: HTH_18; pfam12833
634456004503	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
634456004504	This CD, composed mainly of bacterial single-domain proteins, includes the Thermus thermophilus (Tt) YbaK-like protein, a homolog of the trans-acting Escherichia coli YbaK Cys-tRNA(Pro) deacylase and the Agrobacterium tumefaciens  ProX Ala-tRNA(Pro)...; Region: ProX_deacylase; cd04333
634456004505	putative deacylase active site [active]
634456004506	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
634456004507	putative substrate translocation pore; other site
634456004508	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
634456004509	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cl17326
634456004510	metal binding site 2 [ion binding]; metal-binding site
634456004511	putative DNA binding helix; other site
634456004512	metal binding site 1 [ion binding]; metal-binding site
634456004513	dimer interface [polypeptide binding]; other site
634456004514	structural Zn2+ binding site [ion binding]; other site
634456004515	Periplasmic protein TonB, links inner and outer membranes [Cell envelope biogenesis, outer membrane]; Region: TonB; COG0810
634456004516	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
634456004517	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
634456004518	Biopolymer transport protein ExbD/TolR; Region: ExbD; cl00537
634456004519	MotA/TolQ/ExbB proton channel family; Region: MotA_ExbB; cl00568
634456004520	Uncharacterized iron-regulated membrane protein [Function unknown]; Region: PiuB; COG3182
634456004521	Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; pfam13340
634456004522	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
634456004523	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
634456004524	Uncharacterized iron-regulated membrane protein [Function unknown]; Region: PiuB; COG3182
634456004525	PepSY-associated TM helix; Region: PepSY_TM_1; pfam13172
634456004526	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
634456004527	ligand-binding site [chemical binding]; other site
634456004528	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
634456004529	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
634456004530	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
634456004531	Fe2+-dicitrate sensor, membrane component [Inorganic ion transport and metabolism / Signal transduction mechanisms]; Region: FecR; COG3712
634456004532	FecR protein; Region: FecR; pfam04773
634456004533	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
634456004534	extracytoplasmic-function sigma-70 factor; Validated; Region: PRK07037
634456004535	Sigma-70, region 4; Region: Sigma70_r4_2; pfam08281
634456004536	ferrichrome outer membrane transporter; Provisional; Region: PRK10044
634456004537	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
634456004538	N-terminal plug; other site
634456004539	ligand-binding site [chemical binding]; other site
634456004540	Fe2+-dicitrate sensor, membrane component [Inorganic ion transport and metabolism / Signal transduction mechanisms]; Region: FecR; COG3712
634456004541	FecR protein; Region: FecR; pfam04773
634456004542	Transposase DDE domain group 1; Region: DDE_Tnp_1_4; pfam13701
634456004543	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
634456004544	extracytoplasmic-function sigma-70 factor; Validated; Region: PRK07037
634456004545	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
634456004546	DNA binding residues [nucleotide binding]
634456004547	ABC transporter, substrate-binding protein, aliphatic sulfonates family; Region: SsuA_fam; TIGR01728
634456004548	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
634456004549	substrate binding pocket [chemical binding]; other site
634456004550	membrane-bound complex binding site; other site
634456004551	hinge residues; other site
634456004552	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: TauB; COG1116
634456004553	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
634456004554	Walker A/P-loop; other site
634456004555	ATP binding site [chemical binding]; other site
634456004556	Q-loop/lid; other site
634456004557	ABC transporter signature motif; other site
634456004558	Walker B; other site
634456004559	D-loop; other site
634456004560	H-loop/switch region; other site
634456004561	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
634456004562	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
634456004563	dimer interface [polypeptide binding]; other site
634456004564	conserved gate region; other site
634456004565	putative PBP binding loops; other site
634456004566	ABC-ATPase subunit interface; other site
634456004567	Secretory lipase; Region: LIP; pfam03583
634456004568	taurine dioxygenase; Reviewed; Region: tauD; PRK09553
634456004569	Probable taurine catabolism dioxygenase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: TauD; COG2175
634456004570	active site
634456004571	iron coordination sites [ion binding]; other site
634456004572	substrate binding pocket [chemical binding]; other site
634456004573	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
634456004574	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
634456004575	FOG: Transposase [DNA replication, recombination, and repair]; Region: COG5659
634456004576	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
634456004577	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
634456004578	Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; pfam13340
634456004579	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
634456004580	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
634456004581	D-galactonate transporter; Region: 2A0114; TIGR00893
634456004582	putative substrate translocation pore; other site
634456004583	Domain of unknown function (DUF4104); Region: DUF4104; pfam13372
634456004584	Transposase DDE domain group 1; Region: DDE_Tnp_1_4; pfam13701
634456004585	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
634456004586	Transposase DDE domain group 1; Region: DDE_Tnp_1_4; pfam13701
634456004587	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
634456004588	putative substrate translocation pore; other site
634456004589	DNA-binding transcriptional regulator HcaR; Provisional; Region: PRK09906
634456004590	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
634456004591	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator similar to regulators involved in the catabolism of aromatic compounds, contains type 2 periplasmic binding fold; Region: PBP2_LTTR_aromatics_like_1; cd08447
634456004592	putative dimerization interface [polypeptide binding]; other site
634456004593	putative substrate binding pocket [chemical binding]; other site
634456004594	dihydroxy-acid dehydratase; Provisional; Region: PRK13016
634456004595	HpcH/HpaI aldolase/citrate lyase family; Region: HpcH_HpaI; cl17231
634456004596	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
634456004597	Winged helix-turn helix; Region: HTH_29; pfam13551
634456004598	Integrase core domain; Region: rve; pfam00665
634456004599	Integrase core domain; Region: rve_3; pfam13683
634456004600	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
634456004601	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
634456004602	Transcriptional regulator [Transcription]; Region: LysR; COG0583
634456004603	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
634456004604	LysR substrate binding domain; Region: LysR_substrate; pfam03466
634456004605	dimerization interface [polypeptide binding]; other site
634456004606	Alcohol dehydrogenase, class IV [Energy production and conversion]; Region: EutG; COG1454
634456004607	Iron-containing alcohol dehydrogenases-like; Region: Fe-ADH6; cd08194
634456004608	putative active site [active]
634456004609	metal binding site [ion binding]; metal-binding site
634456004610	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
634456004611	metabolite-proton symporter; Region: 2A0106; TIGR00883
634456004612	putative substrate translocation pore; other site
634456004613	Methylmalonate semialdehyde dehydrogenase and ALDH family members 6A1 and 6B2; Region: ALDH_F6_MMSDH; cd07085
634456004614	methylmalonic acid semialdehyde dehydrogenase; Region: MMSDH; TIGR01722
634456004615	tetrameric interface [polypeptide binding]; other site
634456004616	NAD binding site [chemical binding]; other site
634456004617	catalytic residues [active]
634456004618	ABC transporter periplasmic binding protein, urea carboxylase region; Region: ABC_peri_uca; TIGR03427
634456004619	ABC transporter, substrate-binding protein, aliphatic sulfonates family; Region: SsuA_fam; TIGR01728
634456004620	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
634456004621	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
634456004622	dimer interface [polypeptide binding]; other site
634456004623	conserved gate region; other site
634456004624	putative PBP binding loops; other site
634456004625	ABC-ATPase subunit interface; other site
634456004626	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: TauB; COG1116
634456004627	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
634456004628	Walker A/P-loop; other site
634456004629	ATP binding site [chemical binding]; other site
634456004630	Q-loop/lid; other site
634456004631	ABC transporter signature motif; other site
634456004632	Walker B; other site
634456004633	D-loop; other site
634456004634	H-loop/switch region; other site
634456004635	nickel responsive regulator; Provisional; Region: PRK04460
634456004636	NikR C terminal nickel binding domain; Region: NikR_C; pfam08753
634456004637	urea carboxylase-associated protein 2; Region: urea_degr_2; TIGR03425
634456004638	urea carboxylase-associated protein 1; Region: urea_degr_1; TIGR03424
634456004639	urea carboxylase-associated protein 1; Region: urea_degr_1; TIGR03424
634456004640	Domain of unknown function (DUF1989); Region: DUF1989; pfam09347
634456004641	urea carboxylase; Region: urea_carbox; TIGR02712
634456004642	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
634456004643	ATP-grasp domain; Region: ATP-grasp_4; cl17255
634456004644	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; pfam02785
634456004645	Allophanate hydrolase subunit 2; Region: AHS2; smart00797
634456004646	Allophanate hydrolase subunit 1 [Amino acid transport and metabolism]; Region: DUR1; cl00896
634456004647	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
634456004648	carboxyltransferase (CT) interaction site; other site
634456004649	biotinylation site [posttranslational modification]; other site
634456004650	allophanate hydrolase; Provisional; Region: PRK08186
634456004651	Amidase; Region: Amidase; cl11426
634456004652	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cd00312
634456004653	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
634456004654	Protein of unknown function (DUF4011); Region: DUF4011; pfam13195
634456004655	Part of AAA domain; Region: AAA_19; pfam13245
634456004656	Superfamily I DNA and RNA helicases and helicase subunits [DNA replication, recombination, and repair]; Region: COG1112
634456004657	AAA domain; Region: AAA_30; pfam13604
634456004658	AAA domain; Region: AAA_12; pfam13087
634456004659	Superfamily of nucleases including Short Patch Repair (Vsr) Endonucleases, archaeal Holliday junction resolvases, MutH methy-directed DNA mismatch-repair endonucleases, and catalytic domains of many restriction endonucleases, such as EcoRI, BamHI, and...; Region: Restriction_endonuclease_like; cl00277
634456004660	putative active site [active]
634456004661	Protein of unknown function (DUF3320); Region: DUF3320; pfam11784
634456004662	Acyl-CoA dehydrogenase, N-terminal domain; Region: Acyl-CoA_dh_N; pfam02771
634456004663	Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960
634456004664	Acyl-CoA dehydrogenase; Region: ACAD; cd00567
634456004665	active site
634456004666	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
634456004667	ligand-binding site [chemical binding]; other site
634456004668	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
634456004669	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
634456004670	Heme oxygenase catalyzes the rate limiting step in the degradation of heme to bilirubin, it is essential for recycling of iron from heme. Heme is used as a substrate and cofactor for its own degradation to biliverdin, iron, and carbon monoxide. This...; Region: HemeO; cl17299
634456004671	heme ligand [chemical binding]; other site
634456004672	FOG: Transposase [DNA replication, recombination, and repair]; Region: COG5659
634456004673	Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; pfam13340
634456004674	melibiose:sodium symporter; Provisional; Region: PRK10429; cl15392
634456004675	Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism]; Region: MelB; COG2211
634456004676	FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family; Region: FMN_nitrolo; TIGR03860
634456004677	nitrilotriacetate monoxygenase oxidizes nitrilotriacetate utilizing reduced flavin mononucleotide (FMNH2) and oxygen. The FMNH2 is provided by an NADH:flavin mononucleotide (FMN) oxidorductase that uses NADH to reduce FMN to FMNH2; Region: Nitrilotriacetate_monoxgenase; cd01095
634456004678	active site
634456004679	non-prolyl cis peptide bond; other site
634456004680	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
634456004681	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
634456004682	Flavin Reductases; Region: FlaRed; cl00801
634456004683	MFS transporter, sugar porter (SP) family; Region: SP; TIGR00879
634456004684	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
634456004685	putative substrate translocation pore; other site
634456004686	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4529
634456004687	FAD-NAD(P)-binding; Region: NAD_binding_9; pfam13454
634456004688	alkanesulfonate monooxygenase; Provisional; Region: PRK00719
634456004689	Alkanesulfonate monoxygenase is the monoxygenase of a two-component system that catalyzes the conversion of alkanesulfonates to the corresponding aldehyde and sulfite. Alkanesulfonate monoxygenase (SsuD) has an absolute requirement for reduced flavin...; Region: Alkanesulfonate_monoxygenase; cd01094
634456004690	active site
634456004691	dimer interface [polypeptide binding]; other site
634456004692	non-prolyl cis peptide bond; other site
634456004693	insertion regions; other site
634456004694	(2R)-phospho-3-sulfolactate synthase (ComA); Region: ComA; cl00782
634456004695	nitrilotriacetate monoxygenase oxidizes nitrilotriacetate utilizing reduced flavin mononucleotide (FMNH2) and oxygen. The FMNH2 is provided by an NADH:flavin mononucleotide (FMN) oxidorductase that uses NADH to reduce FMN to FMNH2; Region: Nitrilotriacetate_monoxgenase; cd01095
634456004696	FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family; Region: FMN_nitrolo; TIGR03860
634456004697	active site
634456004698	non-prolyl cis peptide bond; other site
634456004699	sulfur acquisition oxidoreductase, SfnB family; Region: sulfur_SfnB; TIGR04022
634456004700	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
634456004701	active site
634456004702	Acyl-CoA dehydrogenase, N-terminal domain; Region: Acyl-CoA_dh_N; pfam02771
634456004703	Nitroreductase-like family 2. A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and...; Region: Nitroreductase_2; cd02138
634456004704	putative FMN binding site [chemical binding]; other site
634456004705	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
634456004706	Transposase DDE domain group 1; Region: DDE_Tnp_1_4; pfam13701
634456004707	Transposase DDE domain group 1; Region: DDE_Tnp_1_4; pfam13701
634456004708	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
634456004709	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
634456004710	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; pfam04313
634456004711	DEAD-like helicases superfamily; Region: DEXDc; smart00487
634456004712	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
634456004713	ATP binding site [chemical binding]; other site
634456004714	putative Mg++ binding site [ion binding]; other site
634456004715	Transposase DDE domain group 1; Region: DDE_Tnp_1_4; pfam13701
634456004716	type I site-specific deoxyribonuclease, HsdR family; Region: hsdR; TIGR00348
634456004717	Protein of unknown function DUF45; Region: DUF45; pfam01863
634456004718	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
634456004719	DNA-binding interface [nucleotide binding]; DNA binding site
634456004720	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
634456004721	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
634456004722	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
634456004723	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
634456004724	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
634456004725	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
634456004726	Transposase DDE domain group 1; Region: DDE_Tnp_1_4; pfam13701
634456004727	HTH-like domain; Region: HTH_21; pfam13276
634456004728	Integrase core domain; Region: rve; pfam00665
634456004729	Integrase core domain; Region: rve_3; pfam13683
634456004730	Transposase; Region: HTH_Tnp_1; pfam01527
634456004731	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
634456004732	Walker A/P-loop; other site
634456004733	ATP binding site [chemical binding]; other site
634456004734	Q-loop/lid; other site
634456004735	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
634456004736	ABC transporter signature motif; other site
634456004737	Walker B; other site
634456004738	D-loop; other site
634456004739	H-loop/switch region; other site
634456004740	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
634456004741	AAA domain; Region: AAA_21; pfam13304
634456004742	Walker A/P-loop; other site
634456004743	ATP binding site [chemical binding]; other site
634456004744	Q-loop/lid; other site
634456004745	ABC transporter signature motif; other site
634456004746	Walker B; other site
634456004747	D-loop; other site
634456004748	H-loop/switch region; other site
634456004749	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
634456004750	Sodium:dicarboxylate symporter family; Region: SDF; pfam00375
634456004751	thiopurine S-methyltransferase, Se/Te detoxification family; Region: TMPT_Se_Te; TIGR03840
634456004752	glutaredoxin 2; Provisional; Region: PRK10387
634456004753	GST_N family, Glutaredoxin 2 (GRX2) subfamily; composed of bacterial proteins similar to E. coli GRX2, an atypical GRX with a molecular mass of about 24kD, compared with other GRXs which are 9-12kD in size. GRX2 adopts a GST fold containing an N-terminal...; Region: GST_N_GRX2; cd03037
634456004754	C-terminal domain interface [polypeptide binding]; other site
634456004755	GSH binding site (G-site) [chemical binding]; other site
634456004756	catalytic residues [active]
634456004757	putative dimer interface [polypeptide binding]; other site
634456004758	C-terminal, alpha helical domain of Glutaredoxin 2; Region: GST_C_GRX2; cd03199
634456004759	N-terminal domain interface [polypeptide binding]; other site
634456004760	polyol permease family; Region: 2A0118; TIGR00897
634456004761	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
634456004762	putative substrate translocation pore; other site
634456004763	cobalt-precorrin-6A synthase; Reviewed; Region: cbiD; PRK00075
634456004764	Precorrin-4 C11-methyltransferase (CbiF/CobM); Region: Precorrin-4_C11-MT; cd11641
634456004765	active site
634456004766	SAM binding site [chemical binding]; other site
634456004767	homodimer interface [polypeptide binding]; other site
634456004768	Cobalamin synthesis G C-terminus; Region: CbiG_C; pfam01890
634456004769	Precorrin-6Y methyltransferase, the cobalamin biosynthesis enzyme CbiE; Region: Precorrin-6Y-methylase; cd11644
634456004770	active site
634456004771	putative homodimer interface [polypeptide binding]; other site
634456004772	SAM binding site [chemical binding]; other site
634456004773	Precorrin-6B methylase 2 [Coenzyme metabolism]; Region: CobL; COG2242
634456004774	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
634456004775	S-adenosylmethionine binding site [chemical binding]; other site
634456004776	Precorrin-6x reductase [Coenzyme metabolism]; Region: CobK; COG2099
634456004777	Precorrin-6x reductase CbiJ/CobK; Region: CbiJ; pfam02571
634456004778	Precorrin-3B C(17)-methyltransferase (CobJ/CbiH); Region: Precorrin_3B_C17_MT; cd11646
634456004779	active site
634456004780	SAM binding site [chemical binding]; other site
634456004781	homodimer interface [polypeptide binding]; other site
634456004782	Precorrin-2 C20-methyltransferase, also named CobI or CbiL; Region: Precorrin_2_C20_MT; cd11645
634456004783	active site
634456004784	SAM binding site [chemical binding]; other site
634456004785	homodimer interface [polypeptide binding]; other site
634456004786	precorrin-8X methylmutase; Reviewed; Region: cobH; PRK08285
634456004787	Precorrin-8X methylmutase; Region: CbiC; pfam02570
634456004788	precorrin-3B synthase; Region: CobG; TIGR02435
634456004789	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
634456004790	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
634456004791	Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GAT_1; cl00020
634456004792	Stress responsive A/B Barrel Domain; Region: Dabb; smart00886
634456004793	fumarate hydratase; Reviewed; Region: fumC; PRK00485
634456004794	Class II fumarases; Region: Fumarase_classII; cd01362
634456004795	active site
634456004796	tetramer interface [polypeptide binding]; other site
634456004797	Membrane-bound metallopeptidase [Cell division and chromosome partitioning]; Region: COG4942
634456004798	GAF domain; Region: GAF; cl17456
634456004799	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
634456004800	Putative MetA-pathway of phenol degradation; Region: Phenol_MetA_deg; pfam13557
634456004801	membrane-bound PQQ-dependent dehydrogenase, glucose/quinate/shikimate family; Region: PQQ_membr_DH; TIGR03074
634456004802	Membrane-bound PQQ-dependent glucose dehydrogenase; Region: PQQ_mGDH; cd10280
634456004803	Trp docking motif [polypeptide binding]; other site
634456004804	putative active site [active]
634456004805	Outer membrane protein family (DUF1597); Region: DUF1597; pfam07642
634456004806	Sodium/hydrogen exchanger family; Region: Na_H_Exchanger; pfam00999
634456004807	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; COG0475
634456004808	PepSY-associated TM helix; Region: PepSY_TM_3; pfam13706
634456004809	Uncharacterized iron-regulated membrane protein [Function unknown]; Region: PiuB; COG3182
634456004810	PepSY-associated TM helix; Region: PepSY_TM_2; pfam13703
634456004811	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; cl00465
634456004812	Domain of unknown function DUF20; Region: UPF0118; pfam01594
634456004813	Uncharacterized protein involved in outer membrane biogenesis [Cell envelope biogenesis, outer membrane]; Region: AsmA; COG2982
634456004814	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
634456004815	Acetate kinase [Energy production and conversion]; Region: ackA; COG0282
634456004816	propionate/acetate kinase; Provisional; Region: PRK12379
634456004817	bifunctional enoyl-CoA hydratase/phosphate acetyltransferase; Validated; Region: PRK08190
634456004818	phosphate acetyltransferase; Provisional; Region: PRK11890
634456004819	dihydroorotate dehydrogenase 2; Reviewed; Region: PRK07565
634456004820	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
634456004821	phosphate binding site [ion binding]; other site
634456004822	pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric; Region: pyruv_ox_red; TIGR02176
634456004823	Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034
634456004824	dimer interface [polypeptide binding]; other site
634456004825	PYR/PP interface [polypeptide binding]; other site
634456004826	TPP binding site [chemical binding]; other site
634456004827	substrate binding site [chemical binding]; other site
634456004828	Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit [Energy production and conversion]; Region: PorG; COG1014
634456004829	Domain of unknown function; Region: EKR; pfam10371
634456004830	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
634456004831	Thiamine pyrophosphate (TPP family), PFOR_PNO subfamily, TPP-binding module; composed of proteins similar to the single subunit pyruvate ferredoxin oxidoreductase (PFOR) of Desulfovibrio Africanus, present in bacteria and amitochondriate eukaryotes. This...; Region: TPP_PFOR_PNO; cd03377
634456004832	TPP-binding site [chemical binding]; other site
634456004833	dimer interface [polypeptide binding]; other site
634456004834	putative glutamate synthase (NADPH) small subunit; Provisional; Region: PRK12771
634456004835	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
634456004836	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
634456004837	EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; Region: EFh; cl17302
634456004838	Ca2+ binding site [ion binding]; other site
634456004839	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
634456004840	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
634456004841	Predicted membrane protein [Function unknown]; Region: COG1971
634456004842	Domain of unknown function DUF; Region: DUF204; pfam02659
634456004843	Domain of unknown function DUF; Region: DUF204; pfam02659
634456004844	glutathionine S-transferase; Provisional; Region: PRK10542
634456004845	GST_N family, Class Beta subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens; Region: GST_N_Beta; cd03057
634456004846	C-terminal domain interface [polypeptide binding]; other site
634456004847	GSH binding site (G-site) [chemical binding]; other site
634456004848	dimer interface [polypeptide binding]; other site
634456004849	C-terminal, alpha helical domain of Class Beta Glutathione S-transferases; Region: GST_C_Beta; cd03188
634456004850	dimer interface [polypeptide binding]; other site
634456004851	N-terminal domain interface [polypeptide binding]; other site
634456004852	substrate binding pocket (H-site) [chemical binding]; other site
634456004853	FdhD/NarQ family; Region: FdhD-NarQ; pfam02634
634456004854	molybdopterin-guanine dinucleotide biosynthesis protein MobA; Reviewed; Region: mobA; PRK00317
634456004855	MobA catalyzes the formation of molybdopterin guanine dinucleotide; Region: MobA; cd02503
634456004856	GTP binding site; other site
634456004857	Molybdenum is an essential trace element in the form of molybdenum cofactor (Moco) which is associated with the metabolism of nitrogen, carbon and sulfur by redox active enzymes. In E. coli, the synthesis of Moco involves genes from several loci: moa; Region: MobB; cd03116
634456004858	Walker A motif; other site
634456004859	Molybdopterin biosynthesis enzyme [Coenzyme metabolism]; Region: MoeA; COG0303
634456004860	MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoeA; cd00887
634456004861	dimer interface [polypeptide binding]; other site
634456004862	putative functional site; other site
634456004863	putative MPT binding site; other site
634456004864	formate dehydrogenase accessory protein FdhE; Region: FdhE; TIGR01562
634456004865	Protein involved in formate dehydrogenase formation; Region: FdhE; pfam04216
634456004866	Cytochrome b (N-terminus)/b6/petB:  Cytochrome b is a subunit of cytochrome bc1, an 11-subunit mitochondrial respiratory enzyme. Cytochrome b spans the mitochondrial membrane with 8 transmembrane helices (A-H) in eukaryotes. In plants and cyanobacteria; Region: Cytochrome_b_N; cl00859
634456004867	formate dehydrogenase, gamma subunit; Region: formate-DH-gamm; TIGR01583
634456004868	formate dehydrogenase, beta subunit, Fe-S containing; Region: FDH-beta; TIGR01582
634456004869	Formate dehydrogenase N, transmembrane; Region: Form-deh_trans; pfam09163
634456004870	formate dehydrogenase, alpha subunit, proteobacterial-type; Region: formate-DH-alph; TIGR01553
634456004871	Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_Formate-Dh-Na-like; cd02752
634456004872	[4Fe-4S] binding site [ion binding]; other site
634456004873	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
634456004874	Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_Formate-Dh-Na-like; cd02752
634456004875	Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_CT_Formate-Dh-Na-like; cd02792
634456004876	molybdopterin cofactor binding site; other site
634456004877	exopolyphosphatase; Region: exo_poly_only; TIGR03706
634456004878	Ppx/GppA phosphatase family; Region: Ppx-GppA; pfam02541
634456004879	23S rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: FtsJ; COG0293
634456004880	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
634456004881	S-adenosylmethionine binding site [chemical binding]; other site
634456004882	fructokinase; Reviewed; Region: PRK09557
634456004883	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
634456004884	nucleotide binding site [chemical binding]; other site
634456004885	SirA, YedF, and YeeD. Two-layered alpha/beta sandwich domain.  SirA (also known as UvrY,  and YhhP) belongs to a family of bacterial two-component response regulators that controls secondary metabolism and virulence. The other member of this...; Region: SirA_YedF_YeeD; cd00291
634456004886	CPxP  motif; other site
634456004887	exodeoxyribonuclease VII small subunit; Provisional; Region: PRK00977
634456004888	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
634456004889	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
634456004890	substrate binding pocket [chemical binding]; other site
634456004891	chain length determination region; other site
634456004892	substrate-Mg2+ binding site; other site
634456004893	catalytic residues [active]
634456004894	aspartate-rich region 1; other site
634456004895	active site lid residues [active]
634456004896	aspartate-rich region 2; other site
634456004897	1-deoxy-D-xylulose-5-phosphate synthase; Provisional; Region: PRK05444
634456004898	Thiamine pyrophosphate (TPP) family, DXS subfamily, TPP-binding module; 1-Deoxy-D-xylulose-5-phosphate synthase (DXS) is a regulatory enzyme of the mevalonate-independent pathway involved in terpenoid biosynthesis. Terpeniods are plant natural products...; Region: TPP_DXS; cd02007
634456004899	TPP-binding site; other site
634456004900	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
634456004901	PYR/PP interface [polypeptide binding]; other site
634456004902	dimer interface [polypeptide binding]; other site
634456004903	TPP binding site [chemical binding]; other site
634456004904	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
634456004905	Predicted rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: COG1189
634456004906	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
634456004907	RNA binding surface [nucleotide binding]; other site
634456004908	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
634456004909	S-adenosylmethionine binding site [chemical binding]; other site
634456004910	Predicted Fe-S-cluster redox enzyme [General function prediction only]; Region: COG0820
634456004911	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
634456004912	FeS/SAM binding site; other site
634456004913	argininosuccinate synthase; Provisional; Region: PRK13820
634456004914	Argininosuccinate synthase. The Argininosuccinate synthase is a urea cycle enzyme that catalyzes the penultimate step in arginine biosynthesis: the ATP-dependent ligation of citrulline to aspartate to form argininosuccinate, AMP and pyrophosphate .  In...; Region: Argininosuccinate_Synthase; cd01999
634456004915	ANP binding site [chemical binding]; other site
634456004916	Substrate Binding Site II [chemical binding]; other site
634456004917	Substrate Binding Site I [chemical binding]; other site
634456004918	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
634456004919	Cytochrome c; Region: Cytochrom_C; pfam00034
634456004920	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
634456004921	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
634456004922	active site
634456004923	HIGH motif; other site
634456004924	dimer interface [polypeptide binding]; other site
634456004925	KMSKS motif; other site
634456004926	Protein of unknown function (DUF1275); Region: DUF1275; pfam06912
634456004927	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
634456004928	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
634456004929	active site
634456004930	phosphorylation site [posttranslational modification]
634456004931	intermolecular recognition site; other site
634456004932	dimerization interface [polypeptide binding]; other site
634456004933	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
634456004934	DNA binding site [nucleotide binding]
634456004935	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3786
634456004936	NhaP-type Na+/H+ and K+/H+ antiporters [Inorganic ion transport and metabolism]; Region: NhaP; COG0025
634456004937	NOL1/NOP2/sun family; Region: Nol1_Nop2_Fmu; pfam01189
634456004938	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
634456004939	S-adenosylmethionine binding site [chemical binding]; other site
634456004940	inosine 5'-monophosphate dehydrogenase; Reviewed; Region: PRK05567
634456004941	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
634456004942	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the inosine 5' monophosphate dehydrogenase (IMPDH) protein.  IMPDH is an essential enzyme that catalyzes the first step unique to GTP synthesis, playing a...; Region: CBS_pair_IMPDH; cd04601
634456004943	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
634456004944	active site
634456004945	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
634456004946	The substrate-binding domain of an oligopeptide binding protein (OppA2) from the biosynthesis pathway of the beta-lactamase inhibitor clavulanic acid contains the type 2 periplasmic binding fold; Region: PBP2_clavulanate_OppA2; cd08506
634456004947	peptide binding site [polypeptide binding]; other site
634456004948	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
634456004949	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
634456004950	dimer interface [polypeptide binding]; other site
634456004951	conserved gate region; other site
634456004952	ABC-ATPase subunit interface; other site
634456004953	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
634456004954	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
634456004955	dimer interface [polypeptide binding]; other site
634456004956	conserved gate region; other site
634456004957	putative PBP binding loops; other site
634456004958	ABC-ATPase subunit interface; other site
634456004959	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppD; COG0444
634456004960	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
634456004961	Walker A/P-loop; other site
634456004962	ATP binding site [chemical binding]; other site
634456004963	Q-loop/lid; other site
634456004964	ABC transporter signature motif; other site
634456004965	Walker B; other site
634456004966	D-loop; other site
634456004967	H-loop/switch region; other site
634456004968	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
634456004969	ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism]; Region: AppF; COG4608
634456004970	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
634456004971	Walker A/P-loop; other site
634456004972	ATP binding site [chemical binding]; other site
634456004973	Q-loop/lid; other site
634456004974	ABC transporter signature motif; other site
634456004975	Walker B; other site
634456004976	D-loop; other site
634456004977	H-loop/switch region; other site
634456004978	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
634456004979	Dioxygenases related to 2-nitropropane dioxygenase [General function prediction only]; Region: COG2070
634456004980	2-Nitropropane dioxygenase (NPD), one of the nitroalkane oxidizing enzyme families, catalyzes oxidative denitrification of nitroalkanes to their corresponding carbonyl compounds and nitrites. NDP is a member of the NAD(P)H-dependent flavin oxidoreductase...; Region: NPD_like; cd04730
634456004981	FMN binding site [chemical binding]; other site
634456004982	substrate binding site [chemical binding]; other site
634456004983	putative catalytic residue [active]
634456004984	PAP2, bacterial acid phosphatase or class A non-specific acid phosphatases. These enzymes catalyze phosphomonoester hydrolysis, with optimal activity in low pH conditions. They are secreted into the periplasmic space, and their physiological role remains...; Region: PAP2_acid_phosphatase; cd03397
634456004985	active site
634456004986	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
634456004987	Ribonuclease T2 (RNase T2) is a widespread family of secreted RNases found in every organism examined thus far.  This family includes RNase Rh, RNase MC1, RNase LE, and self-incompatibility RNases (S-RNases).  Plant T2 RNases are expressed during leaf...; Region: RNase_T2; cl00208
634456004988	CAS motifs; other site
634456004989	active site
634456004990	Purine nucleoside permease (NUP); Region: NUP; pfam06516
634456004991	Phosphoesterase family; Region: Phosphoesterase; pfam04185
634456004992	Phosphoesterase family; Region: Phosphoesterase; pfam04185
634456004993	Domain of unknown function (DUF756); Region: DUF756; pfam05506
634456004994	Domain of unknown function (DUF756); Region: DUF756; pfam05506
634456004995	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
634456004996	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
634456004997	Protein of unknown function (DUF3500); Region: DUF3500; pfam12006
634456004998	Tannase and feruloyl esterase; Region: Tannase; pfam07519
634456004999	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
634456005000	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
634456005001	Major Facilitator Superfamily; Region: MFS_1; pfam07690
634456005002	putative substrate translocation pore; other site
634456005003	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
634456005004	Siderophore-interacting protein [Inorganic ion transport and metabolism]; Region: ViuB; COG2375
634456005005	Siderophore interacting proteins share the domain structure of the ferredoxin reductase like family. Siderophores are produced in various bacteria (and some plants) to extract iron from hosts. Binding constants are high, so iron can be pilfered from...; Region: siderophore_interacting; cd06193
634456005006	FAD binding pocket [chemical binding]; other site
634456005007	FAD binding motif [chemical binding]; other site
634456005008	phosphate binding motif [ion binding]; other site
634456005009	NAD binding pocket [chemical binding]; other site
634456005010	Predicted O-methyltransferase [General function prediction only]; Region: COG4122
634456005011	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
634456005012	S-adenosylmethionine binding site [chemical binding]; other site
634456005013	Predicted transcriptional regulators [Transcription]; Region: COG1695
634456005014	Transcriptional regulator PadR-like family; Region: PadR; pfam03551
634456005015	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
634456005016	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
634456005017	multidrug resistance protein MdtN; Provisional; Region: PRK10476
634456005018	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
634456005019	HlyD family secretion protein; Region: HlyD_3; pfam13437
634456005020	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
634456005021	Outer membrane efflux protein; Region: OEP; pfam02321
634456005022	B12 binding domain (B12-BD). Most of the members bind different cobalamid derivates, like B12 (adenosylcobamide) or methylcobalamin or methyl-Co(III) 5-hydroxybenzimidazolylcobamide. This domain is found in several enzymes, such as glutamate mutase; Region: B12-binding_like; cl00293
634456005023	B12 binding site [chemical binding]; other site
634456005024	Radical SAM superfamily; Region: Radical_SAM; pfam04055
634456005025	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cl15377
634456005026	FeS/SAM binding site; other site
634456005027	Domain of unknown function (DUF4070); Region: DUF4070; pfam13282
634456005028	Domain of unknown function (DUF4142); Region: DUF4142; pfam13628
634456005029	TonB-dependent siderophore receptor; Region: TonB-siderophor; TIGR01783
634456005030	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
634456005031	N-terminal plug; other site
634456005032	ligand-binding site [chemical binding]; other site
634456005033	Conserved TM helix; Region: TM_helix; pfam05552
634456005034	Mechanosensitive ion channel; Region: MS_channel; pfam00924
634456005035	Glucose/sorbosone dehydrogenases [Carbohydrate transport and metabolism]; Region: COG2133
634456005036	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003; cl12219
634456005037	Cytochrome oxidase subunit II; Region: Cyto_ox_2; pfam02322
634456005038	Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; cl00562
634456005039	cytochrome d terminal oxidase subunit 1; Provisional; Region: PRK15097
634456005040	ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion / Posttranslational modification, protein turnover, chaperones]; Region: CydC; COG4987
634456005041	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
634456005042	Walker A/P-loop; other site
634456005043	ATP binding site [chemical binding]; other site
634456005044	Q-loop/lid; other site
634456005045	ABC transporter signature motif; other site
634456005046	Walker B; other site
634456005047	D-loop; other site
634456005048	H-loop/switch region; other site
634456005049	thiol reductant ABC exporter, CydD subunit; Region: CydD; TIGR02857
634456005050	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
634456005051	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
634456005052	Walker A/P-loop; other site
634456005053	ATP binding site [chemical binding]; other site
634456005054	Q-loop/lid; other site
634456005055	ABC transporter signature motif; other site
634456005056	Walker B; other site
634456005057	D-loop; other site
634456005058	H-loop/switch region; other site
634456005059	Fe(II)-dependent oxygenase superfamily protein; Provisional; Region: PRK05467
634456005060	catecholate siderophore receptor Fiu; Provisional; Region: PRK09840
634456005061	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
634456005062	N-terminal plug; other site
634456005063	ligand-binding site [chemical binding]; other site
634456005064	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
634456005065	Sel1-like repeats; Region: SEL1; smart00671
634456005066	Sel1-like repeats; Region: SEL1; smart00671
634456005067	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
634456005068	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
634456005069	Type II (periplasmic) bacterial L-asparaginase; Region: L-asparaginase_II; cd08964
634456005070	active site
634456005071	homotetramer interface [polypeptide binding]; other site
634456005072	homodimer interface [polypeptide binding]; other site
634456005073	aspartate 4-decarboxylase; Region: asp_4_decarbox; TIGR03801
634456005074	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
634456005075	pyridoxal 5'-phosphate binding site [chemical binding]; other site
634456005076	homodimer interface [polypeptide binding]; other site
634456005077	catalytic residue [active]
634456005078	aspartate-alanine antiporter; Region: Asp_Ala_antiprt; TIGR03802
634456005079	Predicted Permease Membrane Region; Region: Asp-Al_Ex; pfam06826
634456005080	TrkA-C domain; Region: TrkA_C; pfam02080
634456005081	Predicted Permease Membrane Region; Region: Asp-Al_Ex; cl06061
634456005082	Glycosyltransferases, probably involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: COG1215
634456005083	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
634456005084	active site
634456005085	GlcNAc-PI de-N-acetylase; Region: PIG-L; pfam02585
634456005086	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
634456005087	Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960
634456005088	Transposase DDE domain group 1; Region: DDE_Tnp_1_4; pfam13701
634456005089	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
634456005090	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
634456005091	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
634456005092	Walker A/P-loop; other site
634456005093	ATP binding site [chemical binding]; other site
634456005094	Q-loop/lid; other site
634456005095	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
634456005096	ABC transporter signature motif; other site
634456005097	Walker B; other site
634456005098	ABC transporter; Region: ABC_tran_2; pfam12848
634456005099	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
634456005100	Transcriptional regulator [Transcription]; Region: LysR; COG0583
634456005101	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
634456005102	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
634456005103	dimerization interface [polypeptide binding]; other site
634456005104	Transposase DDE domain group 1; Region: DDE_Tnp_1_4; pfam13701
634456005105	Pertactin-like passenger domains (virulence factors) of autotransporter proteins of the type V secretion system. Autotransporters are proteins used by Gram-negative bacteria to transport proteins across their outer membranes. The C-terminal (beta) domain...; Region: PL_Passenger_AT; cd00253
634456005106	Hint domain; Region: Hint_2; pfam13403
634456005107	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
634456005108	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
634456005109	N-terminal plug; other site
634456005110	ligand-binding site [chemical binding]; other site
634456005111	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD1; cd05283
634456005112	Zn-dependent alcohol dehydrogenases [General function prediction only]; Region: AdhP; COG1064
634456005113	putative NAD(P) binding site [chemical binding]; other site
634456005114	putative substrate binding site [chemical binding]; other site
634456005115	catalytic Zn binding site [ion binding]; other site
634456005116	structural Zn binding site [ion binding]; other site
634456005117	dimer interface [polypeptide binding]; other site
634456005118	Transposase DDE domain group 1; Region: DDE_Tnp_1_4; pfam13701
634456005119	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3558
634456005120	SnoaL-like domain; Region: SnoaL_2; pfam12680
634456005121	YciF bacterial stress response protein, ferritin-like iron-binding domain; Region: YciF; cd07909
634456005122	dimerization interface [polypeptide binding]; other site
634456005123	metal binding site [ion binding]; metal-binding site
634456005124	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
634456005125	catalytic core [active]
634456005126	MgtC family; Region: MgtC; pfam02308
634456005127	Protein of unknown function (DUF1275); Region: DUF1275; pfam06912
634456005128	putative CoA-transferase; Provisional; Region: PRK11430
634456005129	CoA-transferase family III; Region: CoA_transf_3; pfam02515
634456005130	putative oxalyl-CoA decarboxylase; Validated; Region: PRK09259
634456005131	Transposase DDE domain group 1; Region: DDE_Tnp_1_4; pfam13701
634456005132	oxalyl-CoA decarboxylase; Region: oxalate_oxc; TIGR03254
634456005133	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
634456005134	PYR/PP interface [polypeptide binding]; other site
634456005135	dimer interface [polypeptide binding]; other site
634456005136	TPP binding site [chemical binding]; other site
634456005137	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
634456005138	Thiamine pyrophosphate (TPP) family, BZL_OCoD_HPCL subfamily, TPP-binding module; composed of proteins similar to benzaldehyde lyase (BZL), oxalyl-CoA decarboxylase (OCoD) and 2-hydroxyphytanoyl-CoA lyase (2-HPCL). Pseudomonas fluorescens biovar I BZL...; Region: TPP_BZL_OCoD_HPCL; cd02004
634456005139	TPP-binding site; other site
634456005140	dimer interface [polypeptide binding]; other site
634456005141	formyl-coenzyme A transferase; Provisional; Region: PRK05398
634456005142	CoA-transferase family III; Region: CoA_transf_3; pfam02515
634456005143	oxidoreductase; Provisional; Region: PRK12742
634456005144	classical (c) SDRs; Region: SDR_c; cd05233
634456005145	NAD(P) binding site [chemical binding]; other site
634456005146	active site
634456005147	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
634456005148	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
634456005149	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) [Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only]; Region: FabG; COG1028
634456005150	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
634456005151	NAD(P) binding site [chemical binding]; other site
634456005152	active site
634456005153	Pyrabactin resistance 1 (PYR1), PYR1-like (PYL), regulatory component of abscisic acid receptors (RCARs), and related proteins; Region: PYR_PYL_RCAR_like; cd07821
634456005154	putative hydrophobic ligand binding site [chemical binding]; other site
634456005155	protein interface [polypeptide binding]; other site
634456005156	gate; other site
634456005157	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
634456005158	Major Facilitator Superfamily; Region: MFS_1; pfam07690
634456005159	putative substrate translocation pore; other site
634456005160	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
634456005161	phosphoglucomutase; Validated; Region: PRK07564
634456005162	This bacterial PGM-like (phosphoglucomutase-like) protein of unknown function belongs to the alpha-D-phosphohexomutase superfamily. The alpha-D-phosphohexomutases include several related enzymes that catalyze a reversible intramolecular phosphoryl...; Region: PGM_like3; cd05801
634456005163	active site
634456005164	substrate binding site [chemical binding]; other site
634456005165	metal binding site [ion binding]; metal-binding site
634456005166	maltose O-acetyltransferase; Provisional; Region: PRK10092
634456005167	Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6...; Region: LbH_MAT_GAT; cd03357
634456005168	active site
634456005169	substrate binding site [chemical binding]; other site
634456005170	trimer interface [polypeptide binding]; other site
634456005171	CoA binding site [chemical binding]; other site
634456005172	Protein of unknown function (DUF1349); Region: DUF1349; pfam07081
634456005173	Hint domain; Region: Hint_2; pfam13403
634456005174	HTH-like domain; Region: HTH_21; pfam13276
634456005175	Integrase core domain; Region: rve; pfam00665
634456005176	Integrase core domain; Region: rve_3; pfam13683
634456005177	Transposase; Region: HTH_Tnp_1; pfam01527
634456005178	Fe2+-dicitrate sensor, membrane component [Inorganic ion transport and metabolism / Signal transduction mechanisms]; Region: FecR; COG3712
634456005179	FecR protein; Region: FecR; pfam04773
634456005180	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
634456005181	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
634456005182	DNA binding residues [nucleotide binding]
634456005183	Nodulin-21 and CCC1-related protein family; Region: Nodulin-21_like_1; cd02432
634456005184	sensor protein QseC; Provisional; Region: PRK10337
634456005185	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
634456005186	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
634456005187	dimer interface [polypeptide binding]; other site
634456005188	phosphorylation site [posttranslational modification]
634456005189	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
634456005190	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
634456005191	active site
634456005192	phosphorylation site [posttranslational modification]
634456005193	intermolecular recognition site; other site
634456005194	dimerization interface [polypeptide binding]; other site
634456005195	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
634456005196	DNA binding site [nucleotide binding]
634456005197	Putative silver efflux pump [Inorganic ion transport and metabolism]; Region: COG3696
634456005198	HlyD family secretion protein; Region: HlyD_2; pfam12700
634456005199	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
634456005200	HlyD family secretion protein; Region: HlyD_3; pfam13437
634456005201	Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: TolC; COG1538
634456005202	Outer membrane efflux protein; Region: OEP; pfam02321
634456005203	acyl-CoA synthetase; Validated; Region: PRK09192
634456005204	Fatty acyl-AMP ligase (FAAL); Region: FAAL; cd05931
634456005205	acyl-activating enzyme (AAE) consensus motif; other site
634456005206	active site
634456005207	Acyl carrier protein [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: AcpP; COG0236
634456005208	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
634456005209	Aminotransferase class I and II; Region: Aminotran_1_2; pfam00155
634456005210	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
634456005211	catalytic residue [active]
634456005212	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
634456005213	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
634456005214	active site
634456005215	metal binding site [ion binding]; metal-binding site
634456005216	Predicted permeases [General function prediction only]; Region: COG0795
634456005217	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
634456005218	Predicted permeases [General function prediction only]; Region: COG0795
634456005219	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
634456005220	Fatty acid hydroxylase superfamily; Region: FA_hydroxylase; cl01132
634456005221	active site
634456005222	MobA-like NTP transferase domain; Region: NTP_transf_3; pfam12804
634456005223	phosphoglycolate phosphatase; Provisional; Region: PRK13222
634456005224	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
634456005225	motif II; other site
634456005226	bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase; Provisional; Region: glmU; PRK14353
634456005227	N-terminal domain of bacterial GlmU; Region: GT2_GlmU_N_bac; cd02540
634456005228	Substrate binding site; other site
634456005229	Mg++ binding site; other site
634456005230	N-acetyl-glucosamine-1-phosphate uridyltransferase (GlmU), C-terminal left-handed beta-helix (LbH) acetyltransferase domain: GlmU is also known as UDP-N-acetylglucosamine pyrophosphorylase. It is a bifunctional bacterial enzyme that catalyzes two...; Region: LbH_GlmU_C; cd03353
634456005231	active site
634456005232	substrate binding site [chemical binding]; other site
634456005233	CoA binding site [chemical binding]; other site
634456005234	glucosamine--fructose-6-phosphate aminotransferase; Reviewed; Region: PRK00331
634456005235	Glutamine amidotransferases class-II (Gn-AT)_GFAT-type. This domain is found at the N-terminus of glucosamine-6P synthase (GlmS, or GFAT in humans).  The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the appropriate substrate. In...; Region: GFAT; cd00714
634456005236	glutaminase active site [active]
634456005237	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
634456005238	dimer interface [polypeptide binding]; other site
634456005239	active site
634456005240	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
634456005241	dimer interface [polypeptide binding]; other site
634456005242	active site
634456005243	FOG: Transposase [DNA replication, recombination, and repair]; Region: COG5659
634456005244	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
634456005245	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
634456005246	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
634456005247	Transposase DDE domain group 1; Region: DDE_Tnp_1_4; pfam13701
634456005248	Protein of unknown function (DUF3108); Region: DUF3108; pfam11306
634456005249	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
634456005250	Transcriptional regulator [Transcription]; Region: IclR; COG1414
634456005251	Bacterial transcriptional regulator; Region: IclR; pfam01614
634456005252	Glutathione (GSH) peroxidase family; tetrameric selenoenzymes that catalyze the reduction of a variety of hydroperoxides including lipid peroxidases, using GSH as a specific electron donor substrate. GSH peroxidase contains one selenocysteine residue per...; Region: GSH_Peroxidase; cd00340
634456005253	catalytic residues [active]
634456005254	dimer interface [polypeptide binding]; other site
634456005255	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
634456005256	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
634456005257	Walker A/P-loop; other site
634456005258	ATP binding site [chemical binding]; other site
634456005259	Q-loop/lid; other site
634456005260	ABC transporter signature motif; other site
634456005261	Walker B; other site
634456005262	D-loop; other site
634456005263	H-loop/switch region; other site
634456005264	lipoprotein releasing system, transmembrane protein, LolC/E family; Region: lolCE; TIGR02212
634456005265	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
634456005266	FtsX-like permease family; Region: FtsX; pfam02687
634456005267	prolyl-tRNA synthetase; Provisional; Region: PRK12325
634456005268	Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ProRS_core_prok; cd00779
634456005269	dimer interface [polypeptide binding]; other site
634456005270	motif 1; other site
634456005271	active site
634456005272	motif 2; other site
634456005273	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
634456005274	active site
634456005275	motif 3; other site
634456005276	ProRS Prolyl-anticodon binding domain, short version found predominantly in bacteria. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding; Region: ProRS_anticodon_short; cd00861
634456005277	anticodon binding site; other site
634456005278	mRNA degradation ribonucleases J1/J2 (metallo-beta-lactamase superfamily) [Translation, ribosomal structure and biogenesis; Replication, recombination and repair]; Region: COG0595
634456005279	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
634456005280	RNA-metabolising metallo-beta-lactamase; Region: RMMBL; pfam07521
634456005281	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
634456005282	nucleotide binding site [chemical binding]; other site
634456005283	Type III pantothenate kinase; Region: Pan_kinase; cl17198
634456005284	Biotin-(acetyl-CoA carboxylase) ligase [Coenzyme metabolism]; Region: BirA; COG0340
634456005285	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; pfam03099
634456005286	Biotin protein ligase C terminal domain; Region: BPL_C; pfam02237
634456005287	NADH:ubiquinone oxidoreductase subunit N; Provisional; Region: PRK05777
634456005288	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
634456005289	NADH:ubiquinone oxidoreductase subunit L; Reviewed; Region: PRK06590
634456005290	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus; Region: Oxidored_q1_N; pfam00662
634456005291	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
634456005292	NADH:ubiquinone oxidoreductase subunit K; Validated; Region: PRK05715
634456005293	NADH:ubiquinone oxidoreductase subunit J; Provisional; Region: PRK06638
634456005294	NADH dehydrogenase subunit J; Provisional; Region: PRK06433
634456005295	NADH dehydrogenase subunit I; Provisional; Region: PRK05888
634456005296	4Fe-4S binding domain; Region: Fer4; cl02805
634456005297	4Fe-4S binding domain; Region: Fer4; pfam00037
634456005298	NADH:ubiquinone oxidoreductase subunit H; Provisional; Region: PRK06076
634456005299	Formate hydrogenlyase subunit 4 [Energy production and conversion]; Region: HyfC; COG0650
634456005300	NADH dehydrogenase subunit G; Validated; Region: PRK09130
634456005301	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
634456005302	catalytic loop [active]
634456005303	iron binding site [ion binding]; other site
634456005304	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Region: NADH-G_4Fe-4S_3; pfam10588
634456005305	MopB_Res_Cmplx1_Nad11: The second domain of the Nad11/75-kDa subunit of the NADH-quinone oxidoreductase/respiratory complex I/NADH dehydrogenase-1(NDH-1) of eukaryotes and the Nqo3/G subunit of alphaproteobacteria NDH-1. The NADH-quinone oxidoreductase...; Region: MopB_Res-Cmplx1_Nad11; cd02773
634456005306	Domain of unknown function (DUF1982); Region: DUF1982; pfam09326
634456005307	NADH dehydrogenase I subunit F; Provisional; Region: PRK13596
634456005308	SLBB domain; Region: SLBB; pfam10531
634456005309	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; Region: NADH_4Fe-4S; pfam10589
634456005310	Respiratory-chain NADH dehydrogenase 24 Kd subunit; Region: Complex1_24kDa; pfam01257
634456005311	TRX-like [2Fe-2S] Ferredoxin (Fd) family, NADH:ubiquinone oxidoreductase (Nuo) subunit E subfamily; Nuo, also called respiratory chain Complex 1, is the entry point for electrons into the respiratory chains of bacteria and the mitochondria of eukaryotes; Region: TRX_Fd_NuoE; cd03064
634456005312	putative dimer interface [polypeptide binding]; other site
634456005313	[2Fe-2S] cluster binding site [ion binding]; other site
634456005314	NADH:ubiquinone oxidoreductase 49 kD subunit 7 [Energy production and conversion]; Region: NuoD; COG0649
634456005315	NADH dehydrogenase subunit D; Validated; Region: PRK06075
634456005316	NADH:ubiquinone oxidoreductase 27 kD subunit [Energy production and conversion]; Region: NuoC; COG0852
634456005317	NADH (or F420H2) dehydrogenase, subunit C; Region: NuoC_fam; TIGR01961
634456005318	NADH dehydrogenase subunit B; Validated; Region: PRK06411
634456005319	NADH-ubiquinone/plastoquinone oxidoreductase, chain 3; Region: Oxidored_q4; cl00535
634456005320	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
634456005321	IHF dimer interface [polypeptide binding]; other site
634456005322	IHF - DNA interface [nucleotide binding]; other site
634456005323	Found in ATP-dependent protease La (LON); Region: LON; smart00464
634456005324	ATP-dependent Lon protease, bacterial type [Posttranslational modification, protein turnover, chaperones]; Region: Lon; COG0466
634456005325	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
634456005326	Walker A motif; other site
634456005327	ATP binding site [chemical binding]; other site
634456005328	Walker B motif; other site
634456005329	arginine finger; other site
634456005330	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
634456005331	ATP-dependent protease ATP-binding subunit ClpX; Provisional; Region: clpX; PRK05342
634456005332	ClpX C4-type zinc finger; Region: zf-C4_ClpX; pfam06689
634456005333	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
634456005334	Walker A motif; other site
634456005335	ATP binding site [chemical binding]; other site
634456005336	Walker B motif; other site
634456005337	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
634456005338	Clp protease; Region: CLP_protease; pfam00574
634456005339	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
634456005340	oligomer interface [polypeptide binding]; other site
634456005341	active site residues [active]
634456005342	trigger factor; Provisional; Region: tig; PRK01490
634456005343	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
634456005344	Bacterial trigger factor protein (TF) C-terminus; Region: Trigger_C; pfam05698
634456005345	Uncharacterized conserved protein [Function unknown]; Region: COG0062
634456005346	B.subtilis YXKO protein of unknown function and related proteins. Based on the conservation of the ATP binding site, the substrate binding site and the Mg2+binding site and structural homology this group is a member of the ribokinase-like superfamily; Region: YXKO-related; cd01171
634456005347	putative substrate binding site [chemical binding]; other site
634456005348	putative ATP binding site [chemical binding]; other site
634456005349	Predicted integral membrane protein [Function unknown]; Region: COG5615
634456005350	Superfamily II DNA and RNA helicases [DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis]; Region: SrmB; COG0513
634456005351	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
634456005352	ATP binding site [chemical binding]; other site
634456005353	Mg++ binding site [ion binding]; other site
634456005354	motif III; other site
634456005355	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
634456005356	nucleotide binding region [chemical binding]; other site
634456005357	ATP-binding site [chemical binding]; other site
634456005358	SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase [Translation, ribosomal structure and biogenesis]; Region: TrmA; COG2265
634456005359	Iron-sulfur cluster assembly accessory protein; Region: TIGR00049
634456005360	FeS assembly SUF system protein; Region: SUF_assoc; TIGR02945
634456005361	NifU homolog involved in Fe-S cluster formation [Energy production and conversion]; Region: IscU; COG0822
634456005362	Iron-sulfur cluster scaffold-like proteins; Region: IscU_like; cd06664
634456005363	trimerization site [polypeptide binding]; other site
634456005364	active site
634456005365	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
634456005366	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
634456005367	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
634456005368	catalytic residue [active]
634456005369	FeS assembly protein SufD; Region: sufD; TIGR01981
634456005370	Uncharacterized protein family (UPF0051); Region: UPF0051; pfam01458
634456005371	ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Region: ABC_FeS_Assembly; cd03217
634456005372	FeS assembly ATPase SufC; Region: sufC; TIGR01978
634456005373	Walker A/P-loop; other site
634456005374	ATP binding site [chemical binding]; other site
634456005375	Q-loop/lid; other site
634456005376	ABC transporter signature motif; other site
634456005377	Walker B; other site
634456005378	D-loop; other site
634456005379	H-loop/switch region; other site
634456005380	cysteine desulfurase activator complex subunit SufB; Provisional; Region: PRK11814
634456005381	putative ABC transporter; Region: ycf24; CHL00085
634456005382	FeS assembly SUF system regulator, gammaproteobacterial; Region: suf_reg_Xantho; TIGR02944
634456005383	Transcriptional regulator; Region: Rrf2; pfam02082
634456005384	Transcriptional regulator; Region: Rrf2; cl17282
634456005385	Protein of unknown function (DUF445); Region: DUF445; pfam04286
634456005386	Peroxin-3; Region: Peroxin-3; pfam04882
634456005387	Phosphoenolpyruvate carboxylase; Region: PEPcase; cl17418
634456005388	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
634456005389	elongation factor G; Reviewed; Region: PRK12739
634456005390	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
634456005391	G1 box; other site
634456005392	putative GEF interaction site [polypeptide binding]; other site
634456005393	GTP/Mg2+ binding site [chemical binding]; other site
634456005394	Switch I region; other site
634456005395	G2 box; other site
634456005396	G3 box; other site
634456005397	Switch II region; other site
634456005398	G4 box; other site
634456005399	G5 box; other site
634456005400	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
634456005401	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
634456005402	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
634456005403	50S ribosomal protein L28; Reviewed; Region: rpmB; PRK00359
634456005404	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
634456005405	ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components [Posttranslational modification, protein turnover, chaperones]; Region: ATM1; COG5265
634456005406	ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; Region: ABCC_ATM1_transporter; cd03253
634456005407	Walker A/P-loop; other site
634456005408	ATP binding site [chemical binding]; other site
634456005409	Q-loop/lid; other site
634456005410	ABC transporter signature motif; other site
634456005411	Walker B; other site
634456005412	D-loop; other site
634456005413	H-loop/switch region; other site
634456005414	Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cl00447
634456005415	nudix motif; other site
634456005416	PII uridylyl-transferase; Provisional; Region: PRK05092
634456005417	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
634456005418	metal binding triad; other site
634456005419	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
634456005420	ACT domain family, ACT_UUR-like_1, includes the first of two C-terminal ACT domains of the bacterial signal-transducing uridylyltransferase /uridylyl-removing (UUR) enzyme, GlnD and related domains; Region: ACT_UUR-like_1; cd04900
634456005421	C-terminal ACT domains of the bacterial signal-transducing uridylyltransferase /uridylyl-removing (UUR) enzyme, GlnD and related domains; Region: ACT_ACR-UUR-like_2; cd04899
634456005422	DNA mismatch repair protein MutS; Provisional; Region: PRK05399
634456005423	MutS domain I; Region: MutS_I; pfam01624
634456005424	MutS domain II; Region: MutS_II; pfam05188
634456005425	MutS domain III; Region: MutS_III; pfam05192
634456005426	MutS domain V; Region: MutS_V; pfam00488
634456005427	Walker A/P-loop; other site
634456005428	ATP binding site [chemical binding]; other site
634456005429	Q-loop/lid; other site
634456005430	ABC transporter signature motif; other site
634456005431	Walker B; other site
634456005432	D-loop; other site
634456005433	H-loop/switch region; other site
634456005434	FOG: TPR repeat [General function prediction only]; Region: NrfG; COG0457
634456005435	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
634456005436	binding surface
634456005437	TPR motif; other site
634456005438	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
634456005439	binding surface
634456005440	TPR motif; other site
634456005441	Zn-dependent carboxypeptidase [Amino acid transport and metabolism]; Region: COG2317
634456005442	Peptidase family M32 includes thermostable carboxypeptidases TaqCP and PfuCP; Region: M32_Taq; cd06460
634456005443	active site
634456005444	Zn binding site [ion binding]; other site
634456005445	Major royal jelly protein; Region: MRJP; pfam03022
634456005446	Threonine synthase [Amino acid transport and metabolism]; Region: ThrC; COG0498
634456005447	Threonine synthase catalyzes the final step of threonine biosynthesis. The conversion of O-phosphohomoserine into threonine and inorganic phosphate is pyridoxal 5'-phosphate dependent. The Thr-synth_1 CD includes members from higher plants; Region: Thr-synth_2; cd01560
634456005448	pyridoxal 5'-phosphate binding site [chemical binding]; other site
634456005449	catalytic residue [active]
634456005450	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
634456005451	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
634456005452	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
634456005453	Predicted Zn-dependent proteases and their inactivated homologs [General function prediction only]; Region: TldD; COG0312
634456005454	Tim44-like domain; Region: Tim44; pfam04280
634456005455	protoheme IX farnesyltransferase; Provisional; Region: PRK04375
634456005456	UbiA prenyltransferase family; Region: UbiA; pfam01040
634456005457	cytochrome c oxidase subunit I; Provisional; Region: COX1; MTH00182
634456005458	cytochrome c oxidase subunit I; Provisional; Region: COX1; MTH00182
634456005459	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
634456005460	S-adenosylmethionine binding site [chemical binding]; other site
634456005461	glutathione synthetase; Provisional; Region: PRK05246
634456005462	Prokaryotic glutathione synthetase, N-terminal domain; Region: GSH-S_N; pfam02951
634456005463	Prokaryotic glutathione synthetase, ATP-grasp domain; Region: GSH-S_ATP; pfam02955
634456005464	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; pfam13231
634456005465	dolichyl-phosphate beta-D-mannosyltransferase; Region: PLN02726
634456005466	DPM1_like represents putative enzymes similar to eukaryotic DPM1; Region: DPM1_like; cd06442
634456005467	Ligand binding site; other site
634456005468	Putative Catalytic site; other site
634456005469	DXD motif; other site
634456005470	Predicted membrane protein [Function unknown]; Region: COG2246
634456005471	GtrA-like protein; Region: GtrA; pfam04138
634456005472	Transcriptional regulators [Transcription]; Region: Lrp; COG1522
634456005473	AsnC-type helix-turn-helix domain; Region: HTH_AsnC-type; pfam13404
634456005474	putative Zn2+ binding site [ion binding]; other site
634456005475	AsnC family; Region: AsnC_trans_reg; pfam01037
634456005476	thioredoxin-disulfide reductase; Region: TRX_reduct; TIGR01292
634456005477	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
634456005478	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
634456005479	Transcriptional regulator [Transcription]; Region: LysR; COG0583
634456005480	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
634456005481	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
634456005482	putative effector binding pocket; other site
634456005483	dimerization interface [polypeptide binding]; other site
634456005484	ROS/MUCR transcriptional regulator protein; Region: ROS_MUCR; pfam05443
634456005485	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
634456005486	IHF - DNA interface [nucleotide binding]; other site
634456005487	IHF dimer interface [polypeptide binding]; other site
634456005488	Domain of unknown function (DUF4130; Region: DUF4130; cl14836
634456005489	Family 4 Uracil-DNA glycosylase (UDG), found exclusively in thermophilic organisms; Region: UDG_F4_TTUDGA_like; cd10030
634456005490	Fe-S cluster binding site [ion binding]; other site
634456005491	active site
634456005492	Uncharacterized membrane protein, putative virulence factor [General function prediction only]; Region: MviN; COG0728
634456005493	MurJ/MviN, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_MurJ_like; cd13123
634456005494	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
634456005495	Domain of unknown function DUF20; Region: UPF0118; pfam01594
634456005496	Helix-Turn-Helix DNA binding domain of putative MlrA-like transcription regulators; Region: HTH_MlrA-like_sg2; cd04765
634456005497	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
634456005498	DNA binding residues [nucleotide binding]
634456005499	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
634456005500	IHF - DNA interface [nucleotide binding]; other site
634456005501	IHF dimer interface [polypeptide binding]; other site
634456005502	3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK09352
634456005503	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
634456005504	dimer interface [polypeptide binding]; other site
634456005505	active site
634456005506	CoA binding pocket [chemical binding]; other site
634456005507	putative phosphate acyltransferase; Provisional; Region: PRK05331
634456005508	50S ribosomal protein L32; Reviewed; Region: rpmF; PRK12286
634456005509	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
634456005510	Uncharacterized ACR, COG1399; Region: DUF177; pfam02620
634456005511	Outer membrane lipoprotein OmlA (small protein A) [Cell envelope biogenesis, outer membrane]; Region: OlmA; COG2913
634456005512	SmpA / OmlA family; Region: SmpA_OmlA; pfam04355
634456005513	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
634456005514	dimerization interface [polypeptide binding]; other site
634456005515	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
634456005516	ATP binding site [chemical binding]; other site
634456005517	Mg2+ binding site [ion binding]; other site
634456005518	G-X-G motif; other site
634456005519	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
634456005520	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
634456005521	active site
634456005522	phosphorylation site [posttranslational modification]
634456005523	intermolecular recognition site; other site
634456005524	dimerization interface [polypeptide binding]; other site
634456005525	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
634456005526	DNA binding site [nucleotide binding]
634456005527	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
634456005528	MarR family; Region: MarR_2; pfam12802
634456005529	rpsU-divergently transcribed protein; Region: diverge_rpsU; TIGR02396
634456005530	COQ9; Region: COQ9; pfam08511
634456005531	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
634456005532	active site
634456005533	catalytic residues [active]
634456005534	metal binding site [ion binding]; metal-binding site
634456005535	30S ribosomal protein S21; Reviewed; Region: rpsU; PRK00270
634456005536	3-isopropylmalate dehydrogenase; Provisional; Region: PRK00772
634456005537	tartrate dehydrogenase; Region: TTC; TIGR02089
634456005538	isopropylmalate isomerase small subunit; Provisional; Region: leuD; PRK01641
634456005539	Aconatase-like swivel domain of 3-isopropylmalate dehydratase and related uncharacterized proteins. 3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate...; Region: IPMI_Swivel; cd01577
634456005540	substrate binding site [chemical binding]; other site
634456005541	3-isopropylmalate dehydratase large subunit; Reviewed; Region: PRK00402
634456005542	3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; Region: IPMI; cd01583
634456005543	substrate binding site [chemical binding]; other site
634456005544	ligand binding site [chemical binding]; other site
634456005545	50S ribosomal protein L19; Provisional; Region: rplS; PRK05338
634456005546	tRNA (guanine-N(1)-)-methyltransferase; Reviewed; Region: trmD; PRK00026
634456005547	16S rRNA-processing protein RimM; Provisional; Region: rimM; PRK00122
634456005548	RimM N-terminal domain; Region: RimM; pfam01782
634456005549	30S ribosomal protein S16; Reviewed; Region: rpsP; PRK00040
634456005550	signal recognition particle protein; Provisional; Region: PRK10867
634456005551	SRP54-type protein, helical bundle domain; Region: SRP54_N; smart00963
634456005552	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
634456005553	P loop; other site
634456005554	GTP binding site [chemical binding]; other site
634456005555	Signal peptide binding domain; Region: SRP_SPB; pfam02978
634456005556	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
634456005557	dimer interface [polypeptide binding]; other site
634456005558	ATP12 chaperone protein; Region: ATP12; pfam07542
634456005559	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
634456005560	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
634456005561	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
634456005562	RNA binding surface [nucleotide binding]; other site
634456005563	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
634456005564	active site
634456005565	recombination factor protein RarA; Reviewed; Region: PRK13342
634456005566	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
634456005567	Walker A motif; other site
634456005568	ATP binding site [chemical binding]; other site
634456005569	Walker B motif; other site
634456005570	arginine finger; other site
634456005571	MgsA AAA+ ATPase C terminal; Region: MgsA_C; pfam12002
634456005572	Outer membrane lipoprotein-sorting protein [Cell envelope biogenesis, outer membrane]; Region: LolA; COG2834
634456005573	Outer membrane lipoprotein carrier protein LolA; Region: LolA; pfam03548
634456005574	4-hydroxybenzoate polyprenyltransferase and related prenyltransferases [Coenzyme metabolism]; Region: UbiA; cl00337
634456005575	UbiA prenyltransferase family; Region: UbiA; pfam01040
634456005576	16S ribosomal RNA methyltransferase RsmE; Provisional; Region: PRK11713
634456005577	RNA methyltransferase, RsmE family; Region: TIGR00046
634456005578	glutamate--cysteine ligase; Region: PLN02611
634456005579	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
634456005580	Major Facilitator Superfamily; Region: MFS_1; pfam07690
634456005581	putative substrate translocation pore; other site
634456005582	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
634456005583	GTP-binding protein Der; Reviewed; Region: PRK00093
634456005584	EngA1 GTPase contains the first domain of EngA; Region: EngA1; cd01894
634456005585	G1 box; other site
634456005586	GTP/Mg2+ binding site [chemical binding]; other site
634456005587	Switch I region; other site
634456005588	G2 box; other site
634456005589	Switch II region; other site
634456005590	G3 box; other site
634456005591	G4 box; other site
634456005592	G5 box; other site
634456005593	EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895
634456005594	G1 box; other site
634456005595	GTP/Mg2+ binding site [chemical binding]; other site
634456005596	Switch I region; other site
634456005597	G2 box; other site
634456005598	G3 box; other site
634456005599	Switch II region; other site
634456005600	G4 box; other site
634456005601	G5 box; other site
634456005602	PQQ-dependent dehydrogenases and related proteins; Region: PQQ_DH_like; cl11493
634456005603	Trp docking motif [polypeptide binding]; other site
634456005604	active site
634456005605	PQQ-like domain; Region: PQQ_2; pfam13360
634456005606	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4649
634456005607	Uncharacterized protein conserved in bacteria (DUF2133); Region: DUF2133; pfam09976
634456005608	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
634456005609	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
634456005610	putative active site [active]
634456005611	This family is most closely related to the GT1 family of glycosyltransferases. WabH in Klebsiella pneumoniae has been shown to transfer a GlcNAc residue from UDP-GlcNAc onto the acceptor GalUA residue in the cellular outer core; Region: GT1_WabH_like; cd03811
634456005612	putative ADP-binding pocket [chemical binding]; other site
634456005613	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
634456005614	Glutamine amidotransferases class-II (GATase) asparagine synthase_B type.  Asparagine synthetase B catalyses the ATP-dependent conversion of aspartate to asparagine. This enzyme is a homodimer, with each monomer composed of a  glutaminase domain and a...; Region: AsnB; cd00712
634456005615	active site
634456005616	dimer interface [polypeptide binding]; other site
634456005617	asparagine synthase (glutamine-hydrolyzing); Region: asn_synth_AEB; TIGR01536
634456005618	The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B  catalyzes the...; Region: Asn_Synthase_B_C; cd01991
634456005619	Ligand Binding Site [chemical binding]; other site
634456005620	Molecular Tunnel; other site
634456005621	Predicted aminomethyltransferase related to GcvT [General function prediction only]; Region: COG0354
634456005622	folate-binding protein YgfZ; Region: ygfZ_signature; TIGR03317
634456005623	Glycine cleavage T-protein C-terminal barrel domain; Region: GCV_T_C; pfam08669
634456005624	phosphoribosyl-AMP cyclohydrolase; Reviewed; Region: hisI; PRK00051
634456005625	lipid-A-disaccharide synthase; Reviewed; Region: lpxB; PRK00025
634456005626	ipid-A-disaccharide synthase; Provisional; Region: PRK14089
634456005627	Sulfate permease and related transporters (MFS superfamily) [Inorganic ion transport and metabolism]; Region: SUL1; COG0659
634456005628	Sulfate transporter family; Region: Sulfate_transp; pfam00916
634456005629	Sulphate Transporter and Anti-Sigma factor antagonist domain of SulP-like sulfate transporters, plays a role in the function and regulation of the transport activity, proposed general NTP binding function; Region: STAS_SulP_like_sulfate_transporter; cd07042
634456005630	putative sulfite oxidase subunit YedZ; Reviewed; Region: PRK05419
634456005631	3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases [Lipid metabolism]; Region: MmsB; COG2084
634456005632	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
634456005633	Isoprenoid Biosynthesis enzymes, Class 1; Region: Isoprenoid_Biosyn_C1; cl00210
634456005634	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
634456005635	Superoxide dismutase [Inorganic ion transport and metabolism]; Region: SodA; COG0605
634456005636	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
634456005637	ATP-dependent chaperone ClpB; Region: chaperone_ClpB; TIGR03346
634456005638	Clp amino terminal domain; Region: Clp_N; pfam02861
634456005639	Clp amino terminal domain; Region: Clp_N; pfam02861
634456005640	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
634456005641	Walker A motif; other site
634456005642	ATP binding site [chemical binding]; other site
634456005643	Walker B motif; other site
634456005644	arginine finger; other site
634456005645	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
634456005646	Walker A motif; other site
634456005647	ATP binding site [chemical binding]; other site
634456005648	Walker B motif; other site
634456005649	arginine finger; other site
634456005650	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
634456005651	Hydrolase of X-linked nucleoside diphosphate N terminal; Region: Nudix_N; pfam12535
634456005652	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_14; cd04672
634456005653	nudix motif; other site
634456005654	GTP-binding protein HflX; Region: GTP_HflX; TIGR03156
634456005655	GTP-binding GTPase N-terminal; Region: GTP-bdg_N; pfam13167
634456005656	HflX GTPase family; Region: HflX; cd01878
634456005657	G1 box; other site
634456005658	GTP/Mg2+ binding site [chemical binding]; other site
634456005659	Switch I region; other site
634456005660	G2 box; other site
634456005661	G3 box; other site
634456005662	Switch II region; other site
634456005663	G4 box; other site
634456005664	G5 box; other site
634456005665	bacterial Hfq-like; Region: Hfq; cd01716
634456005666	hexamer interface [polypeptide binding]; other site
634456005667	Sm1 motif; other site
634456005668	RNA binding site [nucleotide binding]; other site
634456005669	Sm2 motif; other site
634456005670	Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms]; Region: AtoC; COG2204
634456005671	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
634456005672	active site
634456005673	phosphorylation site [posttranslational modification]
634456005674	intermolecular recognition site; other site
634456005675	dimerization interface [polypeptide binding]; other site
634456005676	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
634456005677	Walker A motif; other site
634456005678	ATP binding site [chemical binding]; other site
634456005679	Walker B motif; other site
634456005680	arginine finger; other site
634456005681	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
634456005682	Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation [Signal transduction mechanisms]; Region: NtrY; COG5000
634456005683	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
634456005684	dimerization interface [polypeptide binding]; other site
634456005685	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
634456005686	dimer interface [polypeptide binding]; other site
634456005687	phosphorylation site [posttranslational modification]
634456005688	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
634456005689	ATP binding site [chemical binding]; other site
634456005690	Mg2+ binding site [ion binding]; other site
634456005691	G-X-G motif; other site
634456005692	nitrogen regulation protein NR(I); Region: ntrC; TIGR01818
634456005693	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
634456005694	active site
634456005695	phosphorylation site [posttranslational modification]
634456005696	intermolecular recognition site; other site
634456005697	dimerization interface [polypeptide binding]; other site
634456005698	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
634456005699	Walker A motif; other site
634456005700	ATP binding site [chemical binding]; other site
634456005701	Walker B motif; other site
634456005702	Bacterial regulatory protein, Fis family; Region: HTH_8; cl17420
634456005703	Signal transduction histidine kinase, nitrogen specific [Signal transduction mechanisms]; Region: NtrB; COG3852
634456005704	PAS domain; Region: PAS; smart00091
634456005705	putative active site [active]
634456005706	heme pocket [chemical binding]; other site
634456005707	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
634456005708	dimer interface [polypeptide binding]; other site
634456005709	phosphorylation site [posttranslational modification]
634456005710	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
634456005711	ATP binding site [chemical binding]; other site
634456005712	Mg2+ binding site [ion binding]; other site
634456005713	G-X-G motif; other site
634456005714	putative TIM-barrel protein, nifR3 family; Region: nifR3_yhdG; TIGR00737
634456005715	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
634456005716	FMN binding site [chemical binding]; other site
634456005717	active site
634456005718	catalytic residues [active]
634456005719	substrate binding site [chemical binding]; other site
634456005720	bifunctional 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase/2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase protein; Provisional; Region: ispDF; PRK09382
634456005721	CDP-ME synthetase is involved in mevalonate-independent isoprenoid production; Region: CDP-ME_synthetase; cd02516
634456005722	substrate binding site; other site
634456005723	dimer interface; other site
634456005724	MECDP_synthase (2-C-methyl-D-erythritol-2,4-cyclodiphosphate synthase), encoded by the ispF gene, catalyzes the formation of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (MEC) in the non-mevalonate deoxyxylulose (DOXP) pathway for isoprenoid biosynthesis; Region: MECDP_synthase; cd00554
634456005725	homotrimer interaction site [polypeptide binding]; other site
634456005726	zinc binding site [ion binding]; other site
634456005727	CDP-binding sites; other site
634456005728	undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional; Region: PRK10714
634456005729	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
634456005730	Ligand binding site; other site
634456005731	Putative Catalytic site; other site
634456005732	DXD motif; other site
634456005733	Predicted glycosyltransferases [General function prediction only]; Region: COG1216
634456005734	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
634456005735	active site
634456005736	UDP-galactopyranose mutase [Cell envelope biogenesis, outer membrane]; Region: Glf; COG0562
634456005737	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
634456005738	UDP-galactopyranose mutase; Region: GLF; pfam03275
634456005739	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
634456005740	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
634456005741	active site
634456005742	ETC complex I subunit conserved region; Region: ETC_C1_NDUFA4; pfam04800
634456005743	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
634456005744	active site
634456005745	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
634456005746	This family is most closely related to the GT1 family of glycosyltransferases. mtfB (mannosyltransferase B) in E. coli has been shown to direct the growth of the O9-specific polysaccharide chain. It transfers two mannoses into the position 3 of the...; Region: GT1_mtfB_like; cd03809
634456005747	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
634456005748	active site
634456005749	Predicted UDP-glucose 6-dehydrogenase [Cell envelope biogenesis, outer membrane]; Region: Ugd; COG1004
634456005750	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
634456005751	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
634456005752	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
634456005753	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
634456005754	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
634456005755	Probable transposase; Region: OrfB_IS605; pfam01385
634456005756	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
634456005757	Nitrogen regulatory protein PII [Amino acid transport and metabolism]; Region: GlnK; COG0347
634456005758	Nitrogen regulatory protein P-II; Region: P-II; smart00938
634456005759	serine acetyltransferase; Provisional; Region: cysE; PRK11132
634456005760	Serine acetyltransferase, N-terminal; Region: SATase_N; pfam06426
634456005761	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
634456005762	trimer interface [polypeptide binding]; other site
634456005763	active site
634456005764	substrate binding site [chemical binding]; other site
634456005765	CoA binding site [chemical binding]; other site
634456005766	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
634456005767	Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; Region: Ubi-OHases; TIGR01988
634456005768	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
634456005769	SNARE associated Golgi protein; Region: SNARE_assoc; cl00429
634456005770	Predicted protein tyrosine phosphatase [General function prediction only]; Region: COG5350
634456005771	NADH dehydrogenase I subunit F; Provisional; Region: PRK13596
634456005772	DDE superfamily endonuclease; Region: DDE_5; cl17874
634456005773	elongation factor P; Validated; Region: PRK00529
634456005774	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
634456005775	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
634456005776	RNA binding site [nucleotide binding]; other site
634456005777	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
634456005778	RNA binding site [nucleotide binding]; other site
634456005779	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
634456005780	IMPase, inositol monophosphatase and related domains. A family of Mg++ dependent phosphatases, inhibited by lithium, many of which may act on inositol monophosphate substrate. They dephosphorylate inositol phosphate to generate inositol, which may be...; Region: IMPase; cd01639
634456005781	active site
634456005782	dimerization interface [polypeptide binding]; other site
634456005783	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
634456005784	ATP binding site [chemical binding]; other site
634456005785	Rad3-related DNA helicases [Transcription / DNA replication, recombination, and repair]; Region: DinG; COG1199
634456005786	Helicase C-terminal domain; Region: Helicase_C_2; pfam13307
634456005787	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
634456005788	DNA-binding site [nucleotide binding]; DNA binding site
634456005789	RNA-binding motif; other site
634456005790	Dienelactone hydrolase family; Region: DLH; pfam01738
634456005791	Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320
634456005792	oligomerisation interface [polypeptide binding]; other site
634456005793	mobile loop; other site
634456005794	roof hairpin; other site
634456005795	chaperonin GroEL; Reviewed; Region: groEL; PRK12849
634456005796	GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344
634456005797	ring oligomerisation interface [polypeptide binding]; other site
634456005798	ATP/Mg binding site [chemical binding]; other site
634456005799	stacking interactions; other site
634456005800	hinge regions; other site
634456005801	FkbH-like domain; Region: FkbH; TIGR01686
634456005802	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
634456005803	active site
634456005804	motif I; other site
634456005805	motif II; other site
634456005806	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
634456005807	Transposase; Region: HTH_Tnp_1; pfam01527
634456005808	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
634456005809	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
634456005810	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
634456005811	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
634456005812	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
634456005813	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
634456005814	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
634456005815	Transposase domain (DUF772); Region: DUF772; pfam05598
634456005816	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
634456005817	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
634456005818	HTH-like domain; Region: HTH_21; pfam13276
634456005819	Integrase core domain; Region: rve; pfam00665
634456005820	Integrase core domain; Region: rve_3; pfam13683
634456005821	Transposase; Region: HTH_Tnp_1; pfam01527
634456005822	Transposase DDE domain group 1; Region: DDE_Tnp_1_4; pfam13701
634456005823	Transposase domain (DUF772); Region: DUF772; pfam05598
634456005824	GT2_BcbE_like is likely involved in the biosynthesis of the polysaccharide capsule; Region: GT2_BcE_like; cd04183
634456005825	Ligand binding site; other site
634456005826	Phosphotransferase enzyme family; Region: APH; pfam01636
634456005827	capsule biosynthesis phosphatase; Region: EcbF-BcbF; TIGR01689
634456005828	Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; pfam13340
634456005829	Transposase DDE domain group 1; Region: DDE_Tnp_1_4; pfam13701
634456005830	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3293
634456005831	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
634456005832	Dehydroquinate synthase-like (DHQ-like) and iron-containing alcohol dehydrogenases (Fe-ADH); Region: DHQ_Fe-ADH; cl02872
634456005833	Transposase DDE domain group 1; Region: DDE_Tnp_1_4; pfam13701
634456005834	Transposase DDE domain group 1; Region: DDE_Tnp_1_4; pfam13701
634456005835	GDP-fucose protein O-fucosyltransferase and related proteins; Region: O-FucT_like; cl16914
634456005836	GDP-Fucose binding site [chemical binding]; other site
634456005837	G1P_TT_short is the short form of glucose-1-phosphate thymidylyltransferase; Region: G1P_TT_short; cd02538
634456005838	glucose-1-phosphate thymidylyltransferase, short form; Region: rmlA; TIGR01207
634456005839	substrate binding site; other site
634456005840	tetramer interface; other site
634456005841	dTDP-D-glucose 4,6-dehydratase [Cell envelope biogenesis, outer membrane]; Region: RfbB; COG1088
634456005842	dTDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: dTDP_GD_SDR_e; cd05246
634456005843	NAD binding site [chemical binding]; other site
634456005844	substrate binding site [chemical binding]; other site
634456005845	homodimer interface [polypeptide binding]; other site
634456005846	active site
634456005847	Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; pfam13340
634456005848	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3293
634456005849	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
634456005850	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
634456005851	Transposase DDE domain group 1; Region: DDE_Tnp_1_4; pfam13701
634456005852	FOG: Transposase [DNA replication, recombination, and repair]; Region: COG5659
634456005853	Transposase DDE domain group 1; Region: DDE_Tnp_1_4; pfam13701
634456005854	Transposase DDE domain group 1; Region: DDE_Tnp_1_4; pfam13701
634456005855	FOG: Transposase [DNA replication, recombination, and repair]; Region: COG5659
634456005856	Transposase domain (DUF772); Region: DUF772; pfam05598
634456005857	Transposase DDE domain group 1; Region: DDE_Tnp_1_4; pfam13701
634456005858	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
634456005859	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
634456005860	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
634456005861	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
634456005862	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
634456005863	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
634456005864	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
634456005865	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
634456005866	Transposase; Region: HTH_Tnp_1; pfam01527
634456005867	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
634456005868	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cd00229
634456005869	active site
634456005870	catalytic triad [active]
634456005871	oxyanion hole [active]
634456005872	Glycosyltransferase family 17; Region: Glyco_transf_17; pfam04724
634456005873	Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes; Region: FA58C; cl12042
634456005874	Ammonia permease [Inorganic ion transport and metabolism]; Region: AmtB; COG0004
634456005875	Aspartyl protease; Region: Asp_protease_2; pfam13650
634456005876	inhibitor binding site; inhibition site
634456005877	catalytic motif [active]
634456005878	Catalytic residue [active]
634456005879	Active site flap [active]
634456005880	Cellular and retroviral pepsin-like aspartate proteases; Region: pepsin_retropepsin_like; cl11403
634456005881	inhibitor binding site; inhibition site
634456005882	catalytic motif [active]
634456005883	Catalytic residue [active]
634456005884	Active site flap [active]
634456005885	proline iminopeptidase, Neisseria-type subfamily; Region: pro_imino_pep_1; TIGR01249
634456005886	site-specific tyrosine recombinase XerC; Reviewed; Region: xerC; PRK00236
634456005887	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
634456005888	active site
634456005889	DNA binding site [nucleotide binding]
634456005890	Int/Topo IB signature motif; other site
634456005891	primosome assembly protein PriA; Validated; Region: PRK05580
634456005892	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
634456005893	ATP binding site [chemical binding]; other site
634456005894	putative Mg++ binding site [ion binding]; other site
634456005895	Preprotein translocase subunit; Region: YajC; pfam02699
634456005896	Predicted ATPase (AAA+ superfamily) [General function prediction only]; Region: COG2607
634456005897	Protein of unknown function (DUF815); Region: DUF815; pfam05673
634456005898	Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit [Inorganic ion transport and metabolism / General function prediction only]; Region: HcaE; COG4638
634456005899	Rieske non-heme iron oxygenase (RO) family, N-terminal Rieske domain of the oxygenase alpha subunit; The RO family comprise a large class of aromatic ring-hydroxylating dioxygenases found predominantly in microorganisms. These enzymes enable...; Region: Rieske_RO_Alpha_N; cd03469
634456005900	[2Fe-2S] cluster binding site [ion binding]; other site
634456005901	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
634456005902	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
634456005903	Coenzyme A binding pocket [chemical binding]; other site
634456005904	The MutT pyrophosphohydrolase is a prototypical Nudix hydrolase that catalyzes the hydrolysis of nucleoside and deoxynucleoside triphosphates (NTPs and dNTPs) by substitution at a beta-phosphorus to yield a nucleotide monophosphate (NMP) and inorganic...; Region: MutT_pyrophosphohydrolase; cd03425
634456005905	active site
634456005906	8-oxo-dGMP binding site [chemical binding]; other site
634456005907	nudix motif; other site
634456005908	metal binding site [ion binding]; metal-binding site
634456005909	mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; Region: GMP_PMI; TIGR01479
634456005910	GDP-M1P_Guanylyltransferase catalyzes the formation of GDP-Mannose; Region: GDP-M1P_Guanylyltransferase; cd02509
634456005911	Substrate binding site; other site
634456005912	Mannose-6-phosphate isomerase; Region: MannoseP_isomer; pfam01050
634456005913	O-succinylhomoserine sulfhydrylase; Reviewed; Region: PRK07504
634456005914	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
634456005915	homodimer interface [polypeptide binding]; other site
634456005916	substrate-cofactor binding pocket; other site
634456005917	pyridoxal 5'-phosphate binding site [chemical binding]; other site
634456005918	catalytic residue [active]
634456005919	CO2+/MG2+ efflux protein ApaG; Reviewed; Region: apaG; PRK05461
634456005920	GTP cyclohydrolase I; Provisional; Region: folE; PRK09347
634456005921	GTP cyclohydrolase I; Provisional; Region: PLN03044
634456005922	active site
634456005923	intracellular protease, PfpI family; Region: PfpI; TIGR01382
634456005924	Type 1 glutamine amidotransferase (GATase1)-like domain found in a subgroup of proteins similar to PfpI from Pyrococcus furiosus; Region: GATase1_PfpI_1; cd03169
634456005925	conserved cys residue [active]
634456005926	MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea; Region: MogA_MoaB; cd00886
634456005927	MPT binding site; other site
634456005928	trimer interface [polypeptide binding]; other site
634456005929	Carbohydrate-selective porin, OprB family; Region: OprB; pfam04966
634456005930	Uncharacterized conserved protein [Function unknown]; Region: COG4717
634456005931	DNA repair exonuclease [DNA replication, recombination, and repair]; Region: SbcD; COG0420
634456005932	Mre11 nuclease, N-terminal metallophosphatase domain; Region: MPP_Mre11_N; cd00840
634456005933	active site
634456005934	metal binding site [ion binding]; metal-binding site
634456005935	DNA binding site [nucleotide binding]
634456005936	Fusaric acid resistance protein family; Region: FUSC; pfam04632
634456005937	Bacterial protein of unknown function (DUF939); Region: DUF939; pfam06081
634456005938	Protein of unknown function (DUF1656); Region: DUF1656; pfam07869
634456005939	Multidrug resistance efflux pump [Defense mechanisms]; Region: EmrA; COG1566
634456005940	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
634456005941	HlyD family secretion protein; Region: HlyD_3; pfam13437
634456005942	Protein of unknown function (DUF3297); Region: DUF3297; pfam11730
634456005943	Uncharacterized NAD(FAD)-dependent dehydrogenases [General function prediction only]; Region: HcaD; COG0446
634456005944	hopanoid biosynthesis associated RND transporter like protein HpnN; Region: HpnN; TIGR03480
634456005945	Uncharacterized protein family (UPF0104); Region: UPF0104; cl04219
634456005946	lumazine synthase (6,7-dimethyl-8-ribityllumazine synthase, LS), catalyzes the penultimate step in the biosynthesis of riboflavin (vitamin B2); type-I; Region: Lumazine_synthase-I; cd09209
634456005947	homopentamer interface [polypeptide binding]; other site
634456005948	active site
634456005949	bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein; Provisional; Region: PRK09311
634456005950	3,4-dihydroxy-2-butanone 4-phosphate synthase; Region: DHBP_synthase; pfam00926
634456005951	GTP cyclohydrolase II (RibA).  GTP cyclohydrolase II catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5' phosphate, formate, pyrophosphate (APy), and GMP in the biosynthetic pathway of riboflavin. Riboflavin is the...; Region: GTP_cyclohydro2; cd00641
634456005952	dimerization interface [polypeptide binding]; other site
634456005953	active site
634456005954	riboflavin synthase subunit alpha; Provisional; Region: PRK09289
634456005955	Lumazine binding domain; Region: Lum_binding; pfam00677
634456005956	Lumazine binding domain; Region: Lum_binding; pfam00677
634456005957	Riboflavin-specific deaminase. Riboflavin biosynthesis protein RibD (Diaminohydroxyphosphoribosylaminopyrimidine deaminase) catalyzes the deamination of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, which is an intermediate step in the...; Region: Riboflavin_deaminase-reductase; cd01284
634456005958	catalytic motif [active]
634456005959	Zn binding site [ion binding]; other site
634456005960	RibD C-terminal domain; Region: RibD_C; cl17279
634456005961	cytochrome b; Provisional; Region: CYTB; MTH00145
634456005962	Cytochrome b (N-terminus)/b6/petB:  Cytochrome b is a subunit of cytochrome bc1, an 11-subunit mitochondrial respiratory enzyme. Cytochrome b spans the mitochondrial membrane with 8 transmembrane helices (A-H) in eukaryotes. In plants and cyanobacteria; Region: Cytochrome_b_N; cl00859
634456005963	Qi binding site; other site
634456005964	intrachain domain interface; other site
634456005965	interchain domain interface [polypeptide binding]; other site
634456005966	heme bH binding site [chemical binding]; other site
634456005967	heme bL binding site [chemical binding]; other site
634456005968	Qo binding site; other site
634456005969	interchain domain interface [polypeptide binding]; other site
634456005970	intrachain domain interface; other site
634456005971	Qi binding site; other site
634456005972	Cytochrome b(C-terminal)/b6/petD; Region: Cytochrom_B_C; pfam00032
634456005973	Qo binding site; other site
634456005974	Cytochrome C1 family; Region: Cytochrom_C1; pfam02167
634456005975	Cytochrome c; Region: Cytochrom_C; cl11414
634456005976	ubiquinol-cytochrome c reductase, iron-sulfur subunit; Region: Rieske_proteo; TIGR01416
634456005977	Iron-sulfur protein (ISP) component of the bc(1) complex family, Rieske domain; The Rieske domain is a [2Fe-2S] cluster binding domain involved in electron transfer. The bc(1) complex is a multisubunit enzyme found in many different organisms including...; Region: Rieske_cytochrome_bc1; cd03470
634456005978	[2Fe-2S] cluster binding site [ion binding]; other site
634456005979	Multimeric flavodoxin WrbA [General function prediction only]; Region: WrbA; COG0655
634456005980	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
634456005981	Outer membrane protein family (DUF1597); Region: DUF1597; pfam07642
634456005982	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
634456005983	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cd00312
634456005984	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
634456005985	Hint domain; Region: Hint_2; pfam13403
634456005986	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
634456005987	Restriction endonuclease; Region: Mrr_cat_2; pfam13156
634456005988	Transposase DDE domain group 1; Region: DDE_Tnp_1_4; pfam13701
634456005989	Restriction endonuclease; Region: Mrr_cat_2; pfam13156
634456005990	Predicted helicase [General function prediction only]; Region: COG4889
634456005991	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
634456005992	ATP binding site [chemical binding]; other site
634456005993	putative Mg++ binding site [ion binding]; other site
634456005994	Helicase conserved C-terminal domain; Region: Helicase_C; pfam00271
634456005995	ATP-binding site [chemical binding]; other site
634456005996	Protein of unknown function DUF262; Region: DUF262; pfam03235
634456005997	Uncharacterized conserved protein [Function unknown]; Region: COG1479
634456005998	Protein of unknown function DUF262; Region: DUF262; pfam03235
634456005999	Protein of unknown function (DUF1524); Region: DUF1524; pfam07510
634456006000	Topoisomerase-primase domain. This is a nucleotidyl transferase/hydrolase domain found in type IA, type IIA and type IIB topoisomerases, bacterial DnaG-type primases, small primase-like proteins from bacteria and archaea, OLD family nucleases from...; Region: TOPRIM; cl00718
634456006001	HTH-like domain; Region: HTH_21; pfam13276
634456006002	Integrase core domain; Region: rve; pfam00665
634456006003	Integrase core domain; Region: rve_3; pfam13683
634456006004	Transposase; Region: HTH_Tnp_1; pfam01527
634456006005	50S ribosomal protein L21/unknown domain fusion protein; Provisional; Region: PRK12278
634456006006	50S ribosomal protein L21; Validated; Region: rplU; PRK05573
634456006007	50S ribosomal protein L27; Validated; Region: rpmA; PRK05435
634456006008	GTPase CgtA; Reviewed; Region: obgE; PRK12299
634456006009	GTP1/OBG; Region: GTP1_OBG; pfam01018
634456006010	Obg GTPase; Region: Obg; cd01898
634456006011	G1 box; other site
634456006012	GTP/Mg2+ binding site [chemical binding]; other site
634456006013	Switch I region; other site
634456006014	G2 box; other site
634456006015	G3 box; other site
634456006016	Switch II region; other site
634456006017	G4 box; other site
634456006018	G5 box; other site
634456006019	gamma-glutamyl kinase; Provisional; Region: PRK05429
634456006020	AAK_G5K_ProB: Glutamate-5-kinase (G5K) catalyzes glutamate-dependent ATP cleavage; G5K transfers the terminal phosphoryl group of ATP to the gamma-carboxyl group of glutamate, in the first and controlling step of proline (and, in mammals, ornithine)...; Region: AAK_G5K_ProB; cd04242
634456006021	nucleotide binding site [chemical binding]; other site
634456006022	homotetrameric interface [polypeptide binding]; other site
634456006023	putative phosphate binding site [ion binding]; other site
634456006024	putative allosteric binding site; other site
634456006025	PUA domain; Region: PUA; pfam01472
634456006026	Uncharacterized protein conserved in bacteria (DUF2312); Region: DUF2312; pfam10073
634456006027	glucose-6-phosphate 1-dehydrogenase; Validated; Region: PRK05722
634456006028	Glucose-6-phosphate dehydrogenase, NAD binding domain; Region: G6PD_N; pfam00479
634456006029	Glucose-6-phosphate dehydrogenase, C-terminal domain; Region: G6PD_C; pfam02781
634456006030	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cd00312
634456006031	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
634456006032	substrate binding pocket [chemical binding]; other site
634456006033	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
634456006034	cell division protein MraZ; Reviewed; Region: PRK00326
634456006035	MraZ protein; Region: MraZ; pfam02381
634456006036	16S rRNA m(4)C1402 methyltranserfase; Provisional; Region: PRK00050
634456006037	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
634456006038	S-adenosylmethionine binding site [chemical binding]; other site
634456006039	Predicted secreted (periplasmic) protein [Function unknown]; Region: COG5462
634456006040	stage V sporulation protein D; Region: spoVD_pbp; TIGR02214
634456006041	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
634456006042	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
634456006043	UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Provisional; Region: murE; PRK00139
634456006044	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
634456006045	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
634456006046	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
634456006047	UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanine ligase; Provisional; Region: PRK14093
634456006048	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
634456006049	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
634456006050	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
634456006051	phospho-N-acetylmuramoyl-pentapeptide-transferase; Provisional; Region: mraY; PRK00108
634456006052	Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of...; Region: GT_MraY; cd06852
634456006053	Mg++ binding site [ion binding]; other site
634456006054	putative catalytic motif [active]
634456006055	putative substrate binding site [chemical binding]; other site
634456006056	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional; Region: murD; PRK01390
634456006057	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
634456006058	cell division protein FtsW; Region: ftsW; TIGR02614
634456006059	undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Region: murG; TIGR01133
634456006060	MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide...; Region: GT1_MurG; cd03785
634456006061	active site
634456006062	homodimer interface [polypeptide binding]; other site
634456006063	UDP-N-acetylmuramate--L-alanine ligase; Provisional; Region: murC; PRK00421
634456006064	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
634456006065	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
634456006066	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
634456006067	UDP-N-acetylenolpyruvoylglucosamine reductase; Provisional; Region: murB; PRK13905
634456006068	FAD binding domain; Region: FAD_binding_4; pfam01565
634456006069	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873
634456006070	D-alanine--D-alanine ligase; Reviewed; Region: ddl; PRK01372
634456006071	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
634456006072	ATP-grasp domain; Region: ATP-grasp_4; cl17255
634456006073	Cell division septal protein [Cell envelope biogenesis, outer membrane]; Region: FtsQ; COG1589
634456006074	POTRA domain, FtsQ-type; Region: POTRA_1; pfam08478
634456006075	Cell division protein FtsQ; Region: FtsQ; pfam03799
634456006076	Cell division protein FtsA; Region: FtsA; smart00842
634456006077	cell division protein FtsA; Region: ftsA; TIGR01174
634456006078	Cell division protein FtsA; Region: FtsA; pfam14450
634456006079	cell division protein FtsZ; Validated; Region: PRK09330
634456006080	FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes.  FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at...; Region: FtsZ_type1; cd02201
634456006081	nucleotide binding site [chemical binding]; other site
634456006082	SulA interaction site; other site
634456006083	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Reviewed; Region: lpxC; PRK13186
634456006084	UDP-3-O-acyl N-acetylglycosamine deacetylase; Region: LpxC; pfam03331
634456006085	outer membrane assembly lipoprotein YfiO; Region: OM_YfiO; TIGR03302
634456006086	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
634456006087	binding surface
634456006088	TPR motif; other site
634456006089	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
634456006090	Walker A/P-loop; other site
634456006091	ATP binding site [chemical binding]; other site
634456006092	Q-loop/lid; other site
634456006093	ATPase involved in DNA repair [DNA replication, recombination, and repair]; Region: RecN; COG0497
634456006094	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
634456006095	ABC transporter signature motif; other site
634456006096	Walker B; other site
634456006097	D-loop; other site
634456006098	H-loop/switch region; other site
634456006099	NAD-dependent DNA ligase LigA; Validated; Region: ligA; PRK07956
634456006100	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114
634456006101	nucleotide binding pocket [chemical binding]; other site
634456006102	K-X-D-G motif; other site
634456006103	catalytic site [active]
634456006104	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
634456006105	NAD-dependent DNA ligase C4 zinc finger domain; Region: DNA_ligase_ZBD; pfam03119
634456006106	Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027
634456006107	Dimer interface [polypeptide binding]; other site
634456006108	BRCT sequence motif; other site
634456006109	pyruvate phosphate dikinase; Provisional; Region: PRK09279
634456006110	Pyruvate phosphate dikinase, PEP/pyruvate binding domain; Region: PPDK_N; pfam01326
634456006111	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
634456006112	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
634456006113	PEP synthetase regulatory protein; Provisional; Region: PRK05339
634456006114	Uncharacterized conserved protein [Function unknown]; Region: COG1739
634456006115	Uncharacterized protein family UPF0029; Region: UPF0029; pfam01205
634456006116	Domain of unknown function (DUF1949); Region: DUF1949; pfam09186
634456006117	Class-II DAHP synthetase family; Region: DAHP_synth_2; pfam01474
634456006118	Phosphoribosyltransferase (PRTase) type II; This family contains two enzymes that play an important role in NAD production by either allowing quinolinic acid (QA) , quinolinate phosphoribosyl transferase (QAPRTase), or nicotinic acid (NA), nicotinate...; Region: PRTase_typeII; cl17275
634456006119	nicotinate phosphoribosyltransferase; Provisional; Region: PRK07188
634456006120	active site
634456006121	glutamyl-tRNA synthetase; Provisional; Region: PRK12558
634456006122	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
634456006123	active site
634456006124	HIGH motif; other site
634456006125	nucleotide binding site [chemical binding]; other site
634456006126	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
634456006127	active site
634456006128	KMSKS motif; other site
634456006129	Nicotinamidase/pyrazinamidase (PZase). Nicotinamidase, a ubiquitous enzyme in prokaryotes, converts nicotinamide to nicotinic acid (niacin) and ammonia, which in turn can be recycled to make nicotinamide adenine dinucleotide (NAD). The same enzyme is...; Region: nicotinamidase; cd01011
634456006130	Isochorismatase family; Region: Isochorismatase; pfam00857
634456006131	catalytic triad [active]
634456006132	metal binding site [ion binding]; metal-binding site
634456006133	conserved cis-peptide bond; other site
634456006134	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217
634456006135	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
634456006136	metal-binding site [ion binding]
634456006137	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217
634456006138	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
634456006139	metal-binding site [ion binding]
634456006140	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
634456006141	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
634456006142	motif II; other site
634456006143	copper-resistance protein, CopA family; Region: copper_res_A; TIGR01480
634456006144	Multicopper oxidase; Region: Cu-oxidase_3; pfam07732
634456006145	Multicopper oxidase; Region: Cu-oxidase; pfam00394
634456006146	Multicopper oxidase; Region: Cu-oxidase_2; pfam07731
634456006147	Copper resistance protein B precursor (CopB); Region: CopB; pfam05275
634456006148	ketol-acid reductoisomerase; Provisional; Region: PRK05479
634456006149	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvN; pfam07991
634456006150	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
634456006151	acetolactate synthase 3 regulatory subunit; Reviewed; Region: ilvH; PRK11895
634456006152	N-terminal ACT domain of the Escherichia coli IlvH-like regulatory subunit of acetohydroxyacid synthase (AHAS); Region: ACT_AHAS; cd04878
634456006153	putative valine binding site [chemical binding]; other site
634456006154	dimer interface [polypeptide binding]; other site
634456006155	Small subunit of acetolactate synthase; Region: ALS_ss_C; pfam10369
634456006156	acetolactate synthase 3 catalytic subunit; Validated; Region: PRK09107
634456006157	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
634456006158	PYR/PP interface [polypeptide binding]; other site
634456006159	dimer interface [polypeptide binding]; other site
634456006160	TPP binding site [chemical binding]; other site
634456006161	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
634456006162	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
634456006163	TPP-binding site [chemical binding]; other site
634456006164	dimer interface [polypeptide binding]; other site
634456006165	tRNA delta(2)-isopentenylpyrophosphate transferase [Translation, ribosomal structure and biogenesis]; Region: MiaA; COG0324
634456006166	tRNA dimethylallyltransferase; Region: miaA; TIGR00174
634456006167	Phosphoserine phosphatase [Amino acid transport and metabolism]; Region: SerB; COG0560
634456006168	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
634456006169	motif II; other site
634456006170	Mitochondrial fission ELM1; Region: Mito_fiss_Elm1; pfam06258
634456006171	ATP-dependent RNA helicase SrmB; Provisional; Region: PRK11192
634456006172	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
634456006173	ATP binding site [chemical binding]; other site
634456006174	putative Mg++ binding site [ion binding]; other site
634456006175	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
634456006176	nucleotide binding region [chemical binding]; other site
634456006177	ATP-binding site [chemical binding]; other site
634456006178	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
634456006179	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
634456006180	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
634456006181	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
634456006182	M14 family of metallocarboxypeptidases and related proteins; Region: Peptidase_M14_like; cl11393
634456006183	active site
634456006184	Zn binding site [ion binding]; other site
634456006185	serine hydroxymethyltransferase; Reviewed; Region: glyA; PRK00011
634456006186	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
634456006187	dimer interface [polypeptide binding]; other site
634456006188	active site
634456006189	glycine-pyridoxal phosphate binding site [chemical binding]; other site
634456006190	folate binding site [chemical binding]; other site
634456006191	amino acid transporter; Region: 2A0306; TIGR00909
634456006192	C-terminus of AA_permease; Region: AA_permease_C; pfam13906
634456006193	Porphobilinogen synthase (PBGS), which is also called delta-aminolevulinic acid dehydratase (ALAD), catalyzes the condensation of two 5-aminolevulinic acid (ALA) molecules to form the pyrrole porphobilinogen (PBG), which is the second step in the...; Region: ALAD_PBGS_aspartate_rich; cd04823
634456006194	dimer interface [polypeptide binding]; other site
634456006195	allosteric magnesium binding site [ion binding]; other site
634456006196	active site
634456006197	aspartate-rich active site metal binding site; other site
634456006198	Schiff base residues; other site
634456006199	arginyl-tRNA-protein transferase; Provisional; Region: PRK01305
634456006200	Arginine-tRNA-protein transferase, N terminus; Region: ATE_N; pfam04376
634456006201	Arginine-tRNA-protein transferase, C terminus; Region: ATE_C; pfam04377
634456006202	DNA topoisomerase IV subunit A; Validated; Region: PRK05561
634456006203	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
634456006204	CAP-like domain; other site
634456006205	active site
634456006206	primary dimer interface [polypeptide binding]; other site
634456006207	DNA repair protein RecO; Reviewed; Region: recO; PRK00085
634456006208	Recombination protein O N terminal; Region: RecO_N; pfam11967
634456006209	Recombination protein O C terminal; Region: RecO_C; pfam02565
634456006210	elongation factor Ts; Provisional; Region: tsf; PRK09377
634456006211	UBA/TS-N domain; Region: UBA; pfam00627
634456006212	Elongation factor TS; Region: EF_TS; pfam00889
634456006213	Elongation factor TS; Region: EF_TS; pfam00889
634456006214	Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425
634456006215	rRNA interaction site [nucleotide binding]; other site
634456006216	S8 interaction site; other site
634456006217	putative laminin-1 binding site; other site
634456006218	Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit [Inorganic ion transport and metabolism / General function prediction only]; Region: HcaE; COG4638
634456006219	Rieske non-heme iron oxygenase (RO) family, N-terminal Rieske domain of the oxygenase alpha subunit; The RO family comprise a large class of aromatic ring-hydroxylating dioxygenases found predominantly in microorganisms. These enzymes enable...; Region: Rieske_RO_Alpha_N; cd03469
634456006220	[2Fe-2S] cluster binding site [ion binding]; other site
634456006221	Selenoprotein P, N terminal region; Region: SelP_N; pfam04592
634456006222	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
634456006223	PyridoxaL 5'-Phosphate Dependent Enzymes class IV (PLPDE_IV). This D-amino acid superfamily, one of five classes of PLPDE, consists of branched-chain amino acid aminotransferases (BCAT), D-amino acid transferases (DAAT), and...; Region: PLPDE_IV; cl00224
634456006224	homodimer interface [polypeptide binding]; other site
634456006225	substrate-cofactor binding pocket; other site
634456006226	pyridoxal 5'-phosphate binding site [chemical binding]; other site
634456006227	catalytic residue [active]
634456006228	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
634456006229	Anthranilate/para-aminobenzoate synthases component I [Amino acid transport and metabolism / Coenzyme metabolism]; Region: TrpE; COG0147
634456006230	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
634456006231	DNA polymerase III subunit alpha; Validated; Region: dnaE; PRK05673
634456006232	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III DnaE1; Region: PHP_PolIIIA_DnaE1; cd07433
634456006233	putative active site [active]
634456006234	putative PHP Thumb interface [polypeptide binding]; other site
634456006235	DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485
634456006236	generic binding surface II; other site
634456006237	generic binding surface I; other site
634456006238	Pantoate-beta-alanine ligase; Region: PanC; cd00560
634456006239	pantoate--beta-alanine ligase; Region: panC; TIGR00018
634456006240	active site
634456006241	ATP-binding site [chemical binding]; other site
634456006242	pantoate-binding site; other site
634456006243	HXXH motif; other site
634456006244	This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function.  The conserved domain is similar in structure to chorismate mutase but there is no sequence...; Region: YjgF_YER057c_UK114_like_2; cd06150
634456006245	homotrimer interaction site [polypeptide binding]; other site
634456006246	putative active site [active]
634456006247	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cl17432
634456006248	ABC transporter, substrate-binding protein, aliphatic sulfonates family; Region: SsuA_fam; TIGR01728
634456006249	aspartate aminotransferase; Provisional; Region: PRK05764
634456006250	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
634456006251	pyridoxal 5'-phosphate binding site [chemical binding]; other site
634456006252	homodimer interface [polypeptide binding]; other site
634456006253	catalytic residue [active]
634456006254	aspartate aminotransferase; Provisional; Region: PRK05764
634456006255	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
634456006256	pyridoxal 5'-phosphate binding site [chemical binding]; other site
634456006257	homodimer interface [polypeptide binding]; other site
634456006258	catalytic residue [active]
634456006259	glutamyl-Q tRNA(Asp) synthetase; Reviewed; Region: PRK05710
634456006260	active site
634456006261	HIGH motif; other site
634456006262	nucleotide binding site [chemical binding]; other site
634456006263	active site
634456006264	KMSKS motif; other site
634456006265	Restriction endonuclease [Defense mechanisms]; Region: McrA; COG1403
634456006266	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
634456006267	active site
634456006268	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
634456006269	metal-binding site [ion binding]
634456006270	hopanoid C-3 methylase HpnR; Region: HpnR_B12_rSAM; TIGR04367
634456006271	B12 binding domain_like associated with radical SAM domain. This domain shows similarity with B12 (adenosylcobamide) binding domains found in several enzymes, such as glutamate mutase, methionine synthase and methylmalonyl-CoA mutase, but it lacks the...; Region: radical_SAM_B12_BD; cd02068
634456006272	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
634456006273	FeS/SAM binding site; other site
634456006274	Nucleoside diphosphate kinase Group I (NDPk_I)-like: NDP kinase domains are present in a large family of structurally and functionally conserved proteins from bacteria to humans that generally catalyze the transfer of gamma-phosphates of a nucleoside...; Region: NDPk_I; cd04413
634456006275	active site
634456006276	multimer interface [polypeptide binding]; other site
634456006277	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
634456006278	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
634456006279	Walker A/P-loop; other site
634456006280	ATP binding site [chemical binding]; other site
634456006281	Q-loop/lid; other site
634456006282	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
634456006283	ABC transporter; Region: ABC_tran_2; pfam12848
634456006284	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
634456006285	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
634456006286	Domain of unknown function DUF20; Region: UPF0118; pfam01594
634456006287	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
634456006288	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
634456006289	active site
634456006290	phosphorylation site [posttranslational modification]
634456006291	intermolecular recognition site; other site
634456006292	dimerization interface [polypeptide binding]; other site
634456006293	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
634456006294	DNA binding site [nucleotide binding]
634456006295	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
634456006296	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054
634456006297	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cl00080
634456006298	dimer interface [polypeptide binding]; other site
634456006299	phosphorylation site [posttranslational modification]
634456006300	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
634456006301	ATP binding site [chemical binding]; other site
634456006302	Mg2+ binding site [ion binding]; other site
634456006303	G-X-G motif; other site
634456006304	Protein of unknown function (DUF541); Region: SIMPL; pfam04402
634456006305	translation initiation factor IF-3; Reviewed; Region: infC; PRK00028
634456006306	Translation initiation factor IF-3, N-terminal domain; Region: IF3_N; pfam05198
634456006307	Translation initiation factor IF-3, C-terminal domain; Region: IF3_C; pfam00707
634456006308	threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK00413
634456006309	TGS _ThrRS_N:  ThrRS (threonyl-tRNA Synthetase)  is a class II tRNA synthetase that couples threonine to its cognate tRNA.  In addition to its catalytic and anticodon-binding domains, ThrRS has an N-terminal TGS domain, named after the ThrRS, GTPase, and...; Region: TGS_ThrRS_N; cd01667
634456006310	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
634456006311	Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771
634456006312	active site
634456006313	dimer interface [polypeptide binding]; other site
634456006314	motif 1; other site
634456006315	motif 2; other site
634456006316	motif 3; other site
634456006317	ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860
634456006318	anticodon binding site; other site
634456006319	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
634456006320	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
634456006321	putative active site [active]
634456006322	TPR repeat; Region: TPR_11; pfam13414
634456006323	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
634456006324	binding surface
634456006325	TPR motif; other site
634456006326	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
634456006327	This family is most closely related to the GT1 family of glycosyltransferases. WavL in Vibrio cholerae has been shown to be involved in the biosynthesis of the lipopolysaccharide core; Region: GT1_WavL_like; cd03819
634456006328	putative ADP-binding pocket [chemical binding]; other site
634456006329	inorganic polyphosphate/ATP-NAD kinase; Reviewed; Region: ppnK; PRK04761
634456006330	ATP-NAD kinase; Region: NAD_kinase; pfam01513
634456006331	RNase HI family found mainly in prokaryotes; Region: RNase_HI_prokaryote_like; cd09278
634456006332	RNA/DNA hybrid binding site [nucleotide binding]; other site
634456006333	active site
634456006334	Putative homoserine kinase type II (protein kinase fold) [General function prediction only]; Region: COG2334
634456006335	Homoserine Kinase, type II. Homoserine kinase is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs), RIO kinases, actin-fragmin kinase (AFK), and...; Region: HomoserineK_II; cd05153
634456006336	putative active site [active]
634456006337	putative substrate binding site [chemical binding]; other site
634456006338	ATP binding site [chemical binding]; other site
634456006339	4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Reviewed; Region: ispH; PRK01045
634456006340	4-Hydroxy-3-methylbut-2-enyl diphosphate reductase IspH [Lipid metabolism]; Region: lytB; COG0761
634456006341	Predicted unusual protein kinase [General function prediction only]; Region: AarF; COG0661
634456006342	ABC1 family; Region: ABC1; cl17513
634456006343	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cl17270
634456006344	active site
634456006345	substrate binding site [chemical binding]; other site
634456006346	ATP binding site [chemical binding]; other site
634456006347	oligoendopeptidase, pepF/M3 family; Region: M3_fam_3; TIGR02290
634456006348	Peptidase family M3B Oligopeptidase F (PepF); Region: M3B_PepF_5; cd09610
634456006349	active site
634456006350	Zn binding site [ion binding]; other site
634456006351	glutamate synthase subunit alpha; Provisional; Region: gltB; PRK11750
634456006352	Glutamine amidotransferases class-II (Gn-AT), glutamate synthase (GltS)-type. GltS is a homodimer that synthesizes L-glutamate from 2-oxoglutarate and L-glutamine, an important step in ammonia assimilation in bacteria, cyanobacteria and plants. The...; Region: GltS; cd00713
634456006353	active site
634456006354	dimer interface [polypeptide binding]; other site
634456006355	Glutamate synthase central domain; Region: Glu_syn_central; pfam04898
634456006356	Glutamate synthase (GltS) FMN-binding domain.  GltS is a complex iron-sulfur flavoprotein that catalyzes the reductive synthesis of L-glutamate from 2-oxoglutarate and L-glutamine via intramolecular channelling of ammonia, a reaction in the plant, yeast...; Region: GltS_FMN; cd02808
634456006357	active site
634456006358	FMN binding site [chemical binding]; other site
634456006359	substrate binding site [chemical binding]; other site
634456006360	3Fe-4S cluster binding site [ion binding]; other site
634456006361	gltb_C. This domain is found at the C-terminus of the large subunit (gltB) of glutamate synthase (GltS). GltS encodes a complex iron-sulfur flavoprotein that catalyzes the synthesis of L-glutamate from L-glutamine and 2-oxoglutarate. It requires the...; Region: gltB_C; cd00982
634456006362	domain interface; other site
634456006363	dihydropyrimidine dehydrogenase subunit A; Provisional; Region: PRK11749
634456006364	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
634456006365	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
634456006366	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, subunit 9, 39 kDa, (NDUFA9) -like, atypical (a) SDRs; Region: NDUFA9_like_SDR_a; cd05271
634456006367	Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG0702
634456006368	putative NAD(P) binding site [chemical binding]; other site
634456006369	active site
634456006370	EamA-like transporter family; Region: EamA; pfam00892
634456006371	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
634456006372	EamA-like transporter family; Region: EamA; pfam00892
634456006373	N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: AmiC; COG0860
634456006374	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
634456006375	active site
634456006376	metal binding site [ion binding]; metal-binding site
634456006377	S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453
634456006378	Ribonuclease E/G family; Region: RNase_E_G; pfam10150
634456006379	ATP phosphoribosyltransferase [Amino acid transport and metabolism]; Region: HisG; COG0040
634456006380	ATP phosphoribosyltransferase catalytic subunit; Reviewed; Region: hisG; PRK01686
634456006381	Histidinol dehydrogenase, HisD, E.C 1.1.1.23. Histidinol dehydrogenase catalyzes the last two steps in the L-histidine biosynthesis pathway, which is conserved in bacteria, archaea, fungi, and plants. These last two steps are (i) the NAD-dependent...; Region: Histidinol_dh; cd06572
634456006382	histidinol dehydrogenase; Region: hisD; TIGR00069
634456006383	NAD binding site [chemical binding]; other site
634456006384	dimerization interface [polypeptide binding]; other site
634456006385	product binding site; other site
634456006386	substrate binding site [chemical binding]; other site
634456006387	zinc binding site [ion binding]; other site
634456006388	catalytic residues [active]
634456006389	S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451
634456006390	rRNA binding site [nucleotide binding]; other site
634456006391	predicted 30S ribosome binding site; other site
634456006392	Maf-like protein; Region: Maf; pfam02545
634456006393	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
634456006394	active site
634456006395	dimer interface [polypeptide binding]; other site
634456006396	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
634456006397	RNA binding site [nucleotide binding]; other site
634456006398	Ribonuclease E/G family; Region: RNase_E_G; pfam10150
634456006399	Domain of unknown function (DUF329); Region: DUF329; pfam03884
634456006400	Helix-Turn-Helix DNA binding domain of transcription regulators from the MerR superfamily; Region: HTH_MerR-SF; cl02600
634456006401	lysozyme_like domain.  This contains several members including Soluble Lytic Transglycosylases (SLT), Goose Egg-White Lysozymes (GEWL), Hen Egg-White Lysozymes (HEWL), chitinases, bacteriophage lambda lysozymes, endolysins, autolysins, and chitosanases; Region: lysozyme_like; cl00222
634456006402	catalytic residue [active]
634456006403	protease 2; Provisional; Region: PRK10115
634456006404	phage major capsid protein, HK97 family; Region: major_cap_HK97; TIGR01554
634456006405	Phage capsid family; Region: Phage_capsid; pfam05065
634456006406	Caudovirus prohead protease; Region: Peptidase_U35; pfam04586
634456006407	Phage-related protein [Function unknown]; Region: COG4695
634456006408	Phage portal protein; Region: Phage_portal; pfam04860
634456006409	Phage terminase-like protein, large subunit [General function prediction only]; Region: COG4626
634456006410	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
634456006411	active site
634456006412	Protein of unknown function (DUF3164); Region: DUF3164; pfam11363
634456006413	site-specific tyrosine recombinase XerC; Reviewed; Region: xerC; PRK00236
634456006414	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
634456006415	active site
634456006416	DNA binding site [nucleotide binding]
634456006417	Int/Topo IB signature motif; other site
634456006418	Protein of unknown function (DUF2283); Region: DUF2283; pfam10049
634456006419	Prophage antirepressor [Transcription]; Region: COG3617
634456006420	BRO family, N-terminal domain; Region: Bro-N; smart01040
634456006421	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cl17200
634456006422	Predicted transcriptional regulator [Transcription]; Region: COG2932
634456006423	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
634456006424	Catalytic site [active]
634456006425	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
634456006426	DNA polymerase III, epsilon subunit and related 3'-5' exonucleases [DNA replication, recombination, and repair]; Region: DnaQ; COG0847
634456006427	active site
634456006428	catalytic site [active]
634456006429	substrate binding site [chemical binding]; other site
634456006430	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
634456006431	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
634456006432	non-specific DNA binding site [nucleotide binding]; other site
634456006433	salt bridge; other site
634456006434	sequence-specific DNA binding site [nucleotide binding]; other site
634456006435	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
634456006436	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
634456006437	active site
634456006438	DNA binding site [nucleotide binding]
634456006439	Int/Topo IB signature motif; other site
634456006440	Cytochrome c; Region: Cytochrom_C; pfam00034
634456006441	3beta17beta hydroxysteroid dehydrogenase-like, classical (c) SDRs; Region: 3beta-17beta-HSD_like_SDR_c; cd05341
634456006442	homotetramer interface [polypeptide binding]; other site
634456006443	short chain dehydrogenase; Validated; Region: PRK07069
634456006444	NAD binding site [chemical binding]; other site
634456006445	homodimer interface [polypeptide binding]; other site
634456006446	active site
634456006447	Rhodococcus ruber 6-oxolauric acid dehydrogenase-like; Region: ALDH_CddD_SSP0762; cd07138
634456006448	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
634456006449	NAD binding site [chemical binding]; other site
634456006450	catalytic residues [active]
634456006451	D-lactate dehydrogenase; Provisional; Region: PRK11183
634456006452	FAD binding domain; Region: FAD_binding_4; pfam01565
634456006453	D-lactate dehydrogenase, membrane binding; Region: Lact-deh-memb; pfam09330
634456006454	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4307
634456006455	Uncharacterized protein conserved in bacteria (DUF2248); Region: DUF2248; pfam10005
634456006456	Bacterial transglutaminase-like N-terminal region; Region: Bact_transglu_N; pfam08379
634456006457	Transglutaminase-like enzymes, putative cysteine proteases [Amino acid transport and metabolism]; Region: COG1305
634456006458	Transglutaminase-like superfamily; Region: Transglut_core; pfam01841
634456006459	Uncharacterized conserved protein [Function unknown]; Region: COG2308
634456006460	A predicted alpha-helical domain with a conserved ER motif; Region: Alpha-E; pfam04168
634456006461	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2307
634456006462	nicotinate-nucleotide pyrophosphorylase; Provisional; Region: PRK06106
634456006463	Quinolinate phosphoribosyl transferase (QAPRTase or QPRTase), also called nicotinate-nucleotide pyrophosphorylase, is involved in the de novo synthesis of NAD in both prokaryotes and eukaryotes. It catalyses the reaction of quinolinic acid (QA) with...; Region: QPRTase; cd01572
634456006464	dimerization interface [polypeptide binding]; other site
634456006465	active site
634456006466	quinolinate synthetase; Provisional; Region: PRK09375
634456006467	Uncharacterized conserved protein [General function prediction only]; Region: COG4111
634456006468	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
634456006469	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
634456006470	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox_2; pfam07992
634456006471	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
634456006472	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
634456006473	Mycobacterium tuberculosis succinate-semialdehyde dehydrogenase 1-like; Region: ALDH_SSADH1_GabD1; cd07100
634456006474	NAD(P) binding site [chemical binding]; other site
634456006475	catalytic residues [active]
634456006476	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
634456006477	Major Facilitator Superfamily; Region: MFS_1; pfam07690
634456006478	putative substrate translocation pore; other site
634456006479	Domain of unknown function (DUF336); Region: DUF336; pfam03928
634456006480	Predicted flavoprotein [General function prediction only]; Region: COG0431
634456006481	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
634456006482	Pirin-related protein [General function prediction only]; Region: COG1741
634456006483	Pirin; Region: Pirin; pfam02678
634456006484	Pirin C-terminal cupin domain; Region: Pirin_C; pfam05726
634456006485	LysR family transcriptional regulator; Provisional; Region: PRK14997
634456006486	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
634456006487	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_4; cd08473
634456006488	putative effector binding pocket; other site
634456006489	putative dimerization interface [polypeptide binding]; other site
634456006490	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
634456006491	Biopolymer transport protein ExbD/TolR; Region: ExbD; pfam02472
634456006492	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
634456006493	Biopolymer transport protein ExbD/TolR; Region: ExbD; pfam02472
634456006494	Biopolymer transport proteins [Intracellular trafficking and secretion]; Region: TolQ; COG0811
634456006495	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
634456006496	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
634456006497	TonB-dependent siderophore receptor; Region: TonB-siderophor; TIGR01783
634456006498	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
634456006499	D-galactonate transporter; Region: 2A0114; TIGR00893
634456006500	putative substrate translocation pore; other site
634456006501	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
634456006502	EamA-like transporter family; Region: EamA; cl17759
634456006503	EamA-like transporter family; Region: EamA; pfam00892
634456006504	LamB/YcsF family of  lactam utilization protein; Region: LamB_YcsF_like; cd10787
634456006505	putative active site [active]
634456006506	Allophanate hydrolase subunit 2 [Amino acid transport and metabolism]; Region: DUR1; COG1984
634456006507	Allophanate hydrolase subunit 1; Region: AHS1; smart00796
634456006508	Allophanate hydrolase subunit 1 [Amino acid transport and metabolism]; Region: DUR1; COG2049
634456006509	Short-chain alcohol dehydrogenase of unknown specificity [General function prediction only]; Region: COG4221
634456006510	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
634456006511	NAD(P) binding site [chemical binding]; other site
634456006512	active site
634456006513	acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated; Region: PRK06302
634456006514	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
634456006515	carboxyltransferase (CT) interaction site; other site
634456006516	biotinylation site [posttranslational modification]; other site
634456006517	acetyl-CoA carboxylase biotin carboxylase subunit; Validated; Region: PRK08591
634456006518	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
634456006519	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
634456006520	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
634456006521	Biotin carboxyl carrier protein [Lipid metabolism]; Region: AccB; COG0511
634456006522	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
634456006523	carboxyltransferase (CT) interaction site; other site
634456006524	biotinylation site [posttranslational modification]; other site
634456006525	aspartate aminotransferase; Provisional; Region: PRK05764
634456006526	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
634456006527	pyridoxal 5'-phosphate binding site [chemical binding]; other site
634456006528	homodimer interface [polypeptide binding]; other site
634456006529	catalytic residue [active]
634456006530	nitrogen assimilation transcriptional regulator; Provisional; Region: PRK11233
634456006531	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
634456006532	The C-teminal substrate binding domain of LysR-like nitrogen assimilation control (NAC) protein, contains the type 2 periplasmic binding fold; Region: PBP2_Nac; cd08433
634456006533	putative dimerization interface [polypeptide binding]; other site
634456006534	amidase; Provisional; Region: PRK07056
634456006535	Amidase; Region: Amidase; cl11426
634456006536	short chain dehydrogenase; Provisional; Region: PRK09291
634456006537	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
634456006538	NAD(P) binding site [chemical binding]; other site
634456006539	active site
634456006540	maltooligosyl trehalose synthase; Provisional; Region: PRK14511
634456006541	Alpha amylase catalytic domain found in maltooligosyl trehalose synthase (MTSase); Region: AmyAc_MTSase; cd11336
634456006542	active site
634456006543	catalytic site [active]
634456006544	N-terminal Early set domain associated with the catalytic domain of Maltooligosyl trehalose trehalohydrolase (also called Glycosyltrehalose trehalohydrolase) and similar proteins; Region: E_set_MTHase_like_N; cd02853
634456006545	malto-oligosyltrehalose trehalohydrolase; Region: trehalose_TreZ; TIGR02402
634456006546	Alpha amylase catalytic domain found in Glycosyltrehalose trehalohydrolase (also called Maltooligosyl trehalose Trehalohydrolase); Region: AmyAc_GTHase; cd11325
634456006547	catalytic site [active]
634456006548	active site
634456006549	Domain of unknown function (DUF3459); Region: DUF3459; pfam11941
634456006550	glycogen branching enzyme; Provisional; Region: PRK05402
634456006551	Early set domain associated with the catalytic domain of sugar utilizing enzymes at either the N or C terminus; Region: E_set; cl09101
634456006552	N-terminal Early set domain associated with the catalytic domain of prokaryotic glycogen branching enzyme; Region: E_set_GBE_prok_N; cd02855
634456006553	Alpha amylase catalytic domain found in the Glycogen branching enzyme (also called 1,4-alpha-glucan branching enzyme); Region: AmyAc_Glg_BE; cd11322
634456006554	active site
634456006555	catalytic site [active]
634456006556	Alpha amylase, C-terminal all-beta domain; Region: Alpha-amylase_C; pfam02806
634456006557	glycogen synthase; Provisional; Region: glgA; PRK00654
634456006558	This family is most closely related to the GT1 family of glycosyltransferases. Glycogen synthase catalyzes the formation and elongation of the alpha-1,4-glucose backbone using ADP-glucose, the second and key step of glycogen biosynthesis. This family...; Region: GT1_Glycogen_synthase_DULL1_like; cd03791
634456006559	ADP-binding pocket [chemical binding]; other site
634456006560	homodimer interface [polypeptide binding]; other site
634456006561	glycogen debranching enzyme GlgX; Region: glgX_debranch; TIGR02100
634456006562	N-terminal Early set domain associated with the catalytic domain of Glycogen debranching enzyme and bacterial isoamylase (also called glycogen 6-glucanohydrolase); Region: E_set_GDE_Isoamylase_N; cd02856
634456006563	Alpha amylase catalytic domain found in glycogen debranching enzymes; Region: AmyAc_Glg_debranch; cd11326
634456006564	active site
634456006565	catalytic site [active]
634456006566	short chain dehydrogenase; Provisional; Region: PRK06701
634456006567	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
634456006568	NAD(P) binding site [chemical binding]; other site
634456006569	active site
634456006570	thiamine pyrophosphate protein; Provisional; Region: PRK08273
634456006571	Pyrimidine (PYR) binding domain of POX; Region: TPP_PYR_POX; cd07039
634456006572	PYR/PP interface [polypeptide binding]; other site
634456006573	dimer interface [polypeptide binding]; other site
634456006574	tetramer interface [polypeptide binding]; other site
634456006575	TPP binding site [chemical binding]; other site
634456006576	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
634456006577	Thiamine pyrophosphate (TPP) family, Pyruvate oxidase (POX) subfamily, TPP-binding module; composed of proteins similar to Lactobacillus plantarum POX, which plays a key role in controlling acetate production under aerobic conditions. POX decarboxylates...; Region: TPP_POX; cd02014
634456006578	TPP-binding site [chemical binding]; other site
634456006579	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
634456006580	Transposase; Region: HTH_Tnp_1; pfam01527
634456006581	HTH-like domain; Region: HTH_21; pfam13276
634456006582	Integrase core domain; Region: rve; pfam00665
634456006583	Integrase core domain; Region: rve_3; pfam13683
634456006584	FAD binding domain; Region: FAD_binding_3; pfam01494
634456006585	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
634456006586	Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems [General function prediction only]; Region: COG1999
634456006587	SCO (an acronym for Synthesis of Cytochrome c Oxidase) family; composed of proteins similar to Sco1, a membrane-anchored protein possessing a soluble domain with a TRX fold. Members of this family are required for the proper assembly of cytochrome c...; Region: SCO; cd02968
634456006588	Cu(I) binding site [ion binding]; other site
634456006589	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
634456006590	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
634456006591	N-terminal plug; other site
634456006592	ligand-binding site [chemical binding]; other site
634456006593	Hint domain; Region: Hint_2; pfam13403
634456006594	HTH-like domain; Region: HTH_21; pfam13276
634456006595	Integrase core domain; Region: rve; pfam00665
634456006596	Integrase core domain; Region: rve_3; pfam13683
634456006597	Transposase; Region: HTH_Tnp_1; pfam01527
634456006598	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_31; cd04690
634456006599	nudix motif; other site
634456006600	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
634456006601	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
634456006602	dimerization interface [polypeptide binding]; other site
634456006603	Fusaric acid resistance protein family; Region: FUSC; pfam04632
634456006604	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
634456006605	Lysophospholipase [Lipid metabolism]; Region: PldB; COG2267
634456006606	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
634456006607	Zinc-finger domain; Region: zf-CHCC; pfam10276
634456006608	Disulphide bond corrector protein DsbC; Region: DsbC; cl15830
634456006609	Cytochrome C biogenesis protein transmembrane region; Region: DsbD; cl15788
634456006610	DsbD gamma family; DsbD gamma is the C-terminal periplasmic domain of the bacterial protein DsbD. It contains a CXXC motif in a TRX fold and shuttles the reducing potential from the membrane domain (DsbD beta) to the N-terminal periplasmic domain (DsbD...; Region: DsbDgamma; cd02953
634456006611	DsbD alpha interface [polypeptide binding]; other site
634456006612	catalytic residues [active]
634456006613	Small Multidrug Resistance protein; Region: Multi_Drug_Res; cl00910
634456006614	seryl-tRNA synthetase; Provisional; Region: PRK05431
634456006615	Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403
634456006616	Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme...; Region: SerRS_core; cd00770
634456006617	dimer interface [polypeptide binding]; other site
634456006618	active site
634456006619	motif 1; other site
634456006620	motif 2; other site
634456006621	motif 3; other site
634456006622	Sec-independent protein secretion pathway component TatC [Intracellular trafficking and secretion]; Region: TatC; COG0805
634456006623	sec-independent translocase; Provisional; Region: tatB; PRK00182
634456006624	twin arginine-targeting protein translocase TatB; Region: tatB; TIGR01410
634456006625	Putative transcriptional regulators (Ypuh-like); Region: DUF387; pfam04079
634456006626	Rec8/ScpA/Scc1-like protein (kleisin family) [Replication,    recombination, and repair]; Region: scpA; COG1354
634456006627	Sporulation related domain; Region: SPOR; pfam05036
634456006628	Arginyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Region: ArgS; COG0018
634456006629	Arginyl tRNA synthetase N terminal dom; Region: Arg_tRNA_synt_N; smart01016
634456006630	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
634456006631	active site
634456006632	HIGH motif; other site
634456006633	nucleotide binding site [chemical binding]; other site
634456006634	catalytic core domain of arginyl-tRNA synthetases; Region: ArgRS_core; cd00671
634456006635	KMSK motif region; other site
634456006636	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
634456006637	tRNA binding surface [nucleotide binding]; other site
634456006638	anticodon binding site; other site
634456006639	deoxyguanosinetriphosphate triphosphohydrolase-like protein; Provisional; Region: PRK01286
634456006640	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
634456006641	Zn2+ binding site [ion binding]; other site
634456006642	Mg2+ binding site [ion binding]; other site
634456006643	Phosphohydrolase-associated domain; Region: HD_assoc; pfam13286
634456006644	Fe-S cluster assembly scaffold protein [Posttranslational modification, protein turnover, chaperones]; Region: sufA; COG0316
634456006645	Escherichia coli exonuclease III (ExoIII) and Neisseria meningitides NExo-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases; Region: ExoIII-like_AP-endo; cd09086
634456006646	putative catalytic site [active]
634456006647	putative phosphate binding site [ion binding]; other site
634456006648	active site
634456006649	metal binding site A [ion binding]; metal-binding site
634456006650	DNA binding site [nucleotide binding]
634456006651	putative AP binding site [nucleotide binding]; other site
634456006652	putative metal binding site B [ion binding]; other site
634456006653	Predicted glycosyltransferases [General function prediction only]; Region: COG1216
634456006654	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
634456006655	active site
634456006656	Mitochondrial fission ELM1; Region: Mito_fiss_Elm1; pfam06258
634456006657	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
634456006658	Polysaccharide biosynthesis protein; Region: Polysacc_synt; cl10513
634456006659	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
634456006660	coenzyme PQQ synthesis protein PqqA; Provisional; Region: pqqA; PRK00284
634456006661	pyrroloquinoline quinone biosynthesis protein PqqB; Provisional; Region: PRK05184
634456006662	coenzyme PQQ biosynthesis protein B; Region: PQQ_syn_pqqB; TIGR02108
634456006663	pyrroloquinoline quinone biosynthesis protein PqqC; Provisional; Region: PRK05157
634456006664	Coenzyme PQQ synthesis protein D (PqqD); Region: PqqD; pfam05402
634456006665	pyrroloquinoline quinone biosynthesis protein PqqE; Provisional; Region: PRK05301
634456006666	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
634456006667	FeS/SAM binding site; other site
634456006668	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
634456006669	Ferritin-like superfamily of diiron-containing four-helix-bundle proteins; Region: Ferritin_like; cl00264
634456006670	dinuclear metal binding motif [ion binding]; other site
634456006671	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
634456006672	Clp protease; Region: CLP_protease; pfam00574
634456006673	oligomer interface [polypeptide binding]; other site
634456006674	active site residues [active]
634456006675	aminotransferase; Validated; Region: PRK09148
634456006676	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
634456006677	pyridoxal 5'-phosphate binding site [chemical binding]; other site
634456006678	homodimer interface [polypeptide binding]; other site
634456006679	catalytic residue [active]
634456006680	homoserine dehydrogenase; Provisional; Region: PRK06349
634456006681	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
634456006682	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
634456006683	ACT_HSDH_Hom CD includes the C-terminal ACT domain of the NAD(P)H-dependent, homoserine dehydrogenase (HSDH) and related domains; Region: ACT_HSDH-Hom; cd04881
634456006684	Bacterial fructose-1,6-bisphosphatase, glpX-encoded. A dimeric enzyme dependent on Mg(2+). glpX-encoded FPBase (FBPase class II) differs from other members of the inositol-phosphatase superfamily by permutation of secondary structure elements. The core...; Region: FBPase_glpX; cd01516
634456006685	Bacterial fructose-1,6-bisphosphatase, glpX-encoded; Region: FBPase_glpX; pfam03320
634456006686	putative active site [active]
634456006687	single-stranded-DNA-specific exonuclease RecJ; Region: recJ; TIGR00644
634456006688	DHH family; Region: DHH; pfam01368
634456006689	DHHA1 domain; Region: DHHA1; pfam02272
634456006690	RNA polymerase factor sigma-32; Reviewed; Region: PRK06596
634456006691	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
634456006692	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
634456006693	DNA binding residues [nucleotide binding]
634456006694	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
634456006695	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
634456006696	RNA binding surface [nucleotide binding]; other site
634456006697	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
634456006698	active site
634456006699	ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism]; Region: FepG; COG4779
634456006700	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
634456006701	ABC-ATPase subunit  interface; other site
634456006702	dimer interface [polypeptide binding]; other site
634456006703	putative PBP binding regions; other site
634456006704	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
634456006705	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
634456006706	Walker A/P-loop; other site
634456006707	ATP binding site [chemical binding]; other site
634456006708	Q-loop/lid; other site
634456006709	ABC transporter signature motif; other site
634456006710	Walker B; other site
634456006711	D-loop; other site
634456006712	H-loop/switch region; other site
634456006713	Uncharacterized conserved protein [Function unknown]; Region: COG0397
634456006714	hypothetical protein; Validated; Region: PRK00029
634456006715	branched-chain amino acid aminotransferase; Provisional; Region: PRK13357
634456006716	BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids  leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and...; Region: BCAT_beta_family; cd01557
634456006717	homodimer interface [polypeptide binding]; other site
634456006718	substrate-cofactor binding pocket; other site
634456006719	catalytic residue [active]
634456006720	DNA polymerase I; Provisional; Region: PRK05755
634456006721	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
634456006722	active site
634456006723	metal binding site 1 [ion binding]; metal-binding site
634456006724	putative 5' ssDNA interaction site; other site
634456006725	metal binding site 3; metal-binding site
634456006726	metal binding site 2 [ion binding]; metal-binding site
634456006727	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
634456006728	putative DNA binding site [nucleotide binding]; other site
634456006729	putative metal binding site [ion binding]; other site
634456006730	DEDDy 3'-5' exonuclease domain of Escherichia coli DNA polymerase I and similar bacterial family-A DNA polymerases; Region: DNA_polA_I_Ecoli_like_exo; cd06139
634456006731	active site
634456006732	catalytic site [active]
634456006733	substrate binding site [chemical binding]; other site
634456006734	Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A_pol_I_C; cd08637
634456006735	active site
634456006736	DNA binding site [nucleotide binding]
634456006737	catalytic site [active]
634456006738	Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems [General function prediction only]; Region: COG1999
634456006739	SCO (an acronym for Synthesis of Cytochrome c Oxidase) family; composed of proteins similar to Sco1, a membrane-anchored protein possessing a soluble domain with a TRX fold. Members of this family are required for the proper assembly of cytochrome c...; Region: SCO; cd02968
634456006740	Cu(I) binding site [ion binding]; other site
634456006741	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
634456006742	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
634456006743	putative acyl-acceptor binding pocket; other site
634456006744	proline/glycine betaine transporter; Provisional; Region: PRK10642
634456006745	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
634456006746	putative substrate translocation pore; other site
634456006747	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
634456006748	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
634456006749	Cytochrome oxidase subunit II; Region: Cyto_ox_2; pfam02322
634456006750	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003; cl12219
634456006751	Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; pfam01654
634456006752	Dyp-type peroxidase family; Region: Dyp_perox; pfam04261
634456006753	Encapsulating protein for peroxidase; Region: Linocin_M18; pfam04454
634456006754	L-asparagine permease; Provisional; Region: PRK15049
634456006755	membrane-bound PQQ-dependent dehydrogenase, glucose/quinate/shikimate family; Region: PQQ_membr_DH; TIGR03074
634456006756	Membrane-bound PQQ-dependent glucose dehydrogenase; Region: PQQ_mGDH; cd10280
634456006757	Trp docking motif [polypeptide binding]; other site
634456006758	putative active site [active]
634456006759	Hint domain; Region: Hint_2; pfam13403
634456006760	4-Oxalocrotonate Tautomerase:  Catalyzes the isomerization of unsaturated ketones. The structure is a homohexamer that is arranged as a trimer of dimers. The hexamer contains six active sites, each formed by residues from three monomers, two from one...; Region: 4Oxalocrotonate_Tautomerase; cl00235
634456006761	beta alanine--pyruvate transaminase; Provisional; Region: PRK09221
634456006762	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
634456006763	inhibitor-cofactor binding pocket; inhibition site
634456006764	pyridoxal 5'-phosphate binding site [chemical binding]; other site
634456006765	catalytic residue [active]
634456006766	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
634456006767	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
634456006768	DNA-binding site [nucleotide binding]; DNA binding site
634456006769	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
634456006770	pyridoxal 5'-phosphate binding site [chemical binding]; other site
634456006771	homodimer interface [polypeptide binding]; other site
634456006772	catalytic residue [active]
634456006773	allantoate amidohydrolase; Reviewed; Region: PRK09290
634456006774	M20 Peptidase beta-alanine synthase, an amidohydrolase; Region: M20_bAS; cd03884
634456006775	active site
634456006776	metal binding site [ion binding]; metal-binding site
634456006777	dimer interface [polypeptide binding]; other site
634456006778	dihydropyrimidine dehydrogenase subunit B; Validated; Region: PRK08318
634456006779	Dihydropyrimidine dehydrogenase (DHPD) FMN-binding domain.  DHPD catalyzes the first step in pyrimidine degradation: the NADPH-dependent reduction of uracil and thymine to the corresponding 5,6-dihydropyrimidines. DHPD contains two FAD, two FMN, and...; Region: DHPD_FMN; cd02940
634456006780	homodimer interface [polypeptide binding]; other site
634456006781	active site
634456006782	FMN binding site [chemical binding]; other site
634456006783	substrate binding site [chemical binding]; other site
634456006784	4Fe-4S binding domain; Region: Fer4; pfam00037
634456006785	dihydropyrimidine dehydrogenase subunit A; Provisional; Region: PRK11749
634456006786	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
634456006787	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
634456006788	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
634456006789	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
634456006790	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
634456006791	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
634456006792	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
634456006793	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
634456006794	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
634456006795	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
634456006796	Transposase; Region: HTH_Tnp_1; pfam01527
634456006797	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
634456006798	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
634456006799	2OG-Fe(II) oxygenase superfamily; Region: 2OG-FeII_Oxy_3; cl17304
634456006800	phenylhydantoinase; Validated; Region: PRK08323
634456006801	D-hydantoinases (D-HYD) also called dihydropyrimidases (DHPase) and related proteins; DHPases are a family of enzymes that catalyze the reversible hydrolytic ring opening of the amide bond in five- or six-membered cyclic diamides, like dihydropyrimidine...; Region: D-HYD; cd01314
634456006802	tetramer interface [polypeptide binding]; other site
634456006803	active site
634456006804	Solute carrier families 5 and 6-like; solute binding domain; Region: SLC5-6-like_sbd; cl00456
634456006805	uncharacterized nucleobase-cation-symport-1 (NCS1) transporter subfamily; solute-binding domain; Region: SLC-NCS1sbd_u1; cd11555
634456006806	Permease for cytosine/purines, uracil, thiamine, allantoin; Region: Transp_cyt_pur; pfam02133
634456006807	putative substrate binding site [chemical binding]; other site
634456006808	Na binding site [ion binding]; other site
634456006809	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
634456006810	YcdC-like protein, C-terminal region; Region: TetR_C_3; pfam08362
634456006811	Phosphoribosylanthranilate isomerase (PRAI) catalyzes the fourth step of the tryptophan biosynthesis, the conversion of N-(5'- phosphoribosyl)-anthranilate (PRA) to 1-(o-carboxyphenylamino)- 1-deoxyribulose 5-phosphate (CdRP). Most PRAIs are...; Region: PRAI; cd00405
634456006812	active site
634456006813	Orotidine 5'-phosphate decarboxylase (ODCase) is a dimeric enzyme that decarboxylates orotidine 5'-monophosphate (OMP) to form uridine 5'-phosphate (UMP), an essential step in the pyrimidine biosynthetic pathway. In mammals, UMP synthase...; Region: OMP_decarboxylase_like; cd04725
634456006814	active site
634456006815	dimer interface [polypeptide binding]; other site
634456006816	Preprotein translocase subunit SecB; Region: SecB; pfam02556
634456006817	SecA binding site; other site
634456006818	Preprotein binding site; other site
634456006819	4-hydroxythreonine-4-phosphate dehydrogenase; Provisional; Region: pdxA; PRK05312
634456006820	4-hydroxythreonine-4-phosphate dehydrogenase; Validated; Region: pdxA; PRK03743
634456006821	Pyridoxine 5'-phosphate (PNP) synthase domain; pyridoxal 5'-phosphate is the active form of vitamin B6 that acts as an essential, ubiquitous coenzyme in amino acid metabolism. In bacteria, formation of pyridoxine 5'-phosphate is a step in...; Region: PNPsynthase; cd00003
634456006822	active site
634456006823	hydrophilic channel; other site
634456006824	catalytic residues [active]
634456006825	active site lid [active]
634456006826	anhydro-N-acetylmuramic acid kinase; Reviewed; Region: anmK; PRK09585
634456006827	Protein of unknown function (DUF3311); Region: DUF3311; pfam11755
634456006828	Na+/proline symporter [Amino acid transport and metabolism / General function prediction only]; Region: PutP; COG0591
634456006829	Na binding site [ion binding]; other site
634456006830	Predicted nuclease of the RNAse H fold, HicB family [General    function prediction only]; Region: HicB; COG4226
634456006831	alpha-ketoglutarate-dependent dioxygenase AlkB; Provisional; Region: PRK15401
634456006832	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
634456006833	Beta-lactamase; Region: Beta-lactamase; pfam00144
634456006834	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
634456006835	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
634456006836	non-specific DNA binding site [nucleotide binding]; other site
634456006837	salt bridge; other site
634456006838	sequence-specific DNA binding site [nucleotide binding]; other site
634456006839	bifunctional nitric oxide dioxygenase/dihydropteridine reductase 2; Provisional; Region: PRK13289
634456006840	Globins are heme proteins, which bind and transport oxygen. This family summarizes a diverse set of homologous protein domains, including: (1) tetrameric vertebrate hemoglobins, which are the major protein component of erythrocytes and transport oxygen...; Region: globin; cd01040
634456006841	heme-binding site [chemical binding]; other site
634456006842	FAD_NAD(P)H binding domain of flavohemoglobin. Flavohemoglobins have a globin domain containing a B-type heme fused with a ferredoxin reductase-like FAD/NAD-binding domain. Flavohemoglobins detoxify nitric oxide (NO) via an NO dioxygenase reaction. The...; Region: flavohem_like_fad_nad_binding; cd06184
634456006843	FAD binding pocket [chemical binding]; other site
634456006844	FAD binding motif [chemical binding]; other site
634456006845	phosphate binding motif [ion binding]; other site
634456006846	beta-alpha-beta structure motif; other site
634456006847	NAD binding pocket [chemical binding]; other site
634456006848	Heme binding  pocket [chemical binding]; other site
634456006849	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
634456006850	dimer interface [polypeptide binding]; other site
634456006851	conserved gate region; other site
634456006852	putative PBP binding loops; other site
634456006853	ABC-ATPase subunit interface; other site
634456006854	ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258
634456006855	DL-methionine transporter ATP-binding subunit; Provisional; Region: metN; PRK11153
634456006856	Walker A/P-loop; other site
634456006857	ATP binding site [chemical binding]; other site
634456006858	Q-loop/lid; other site
634456006859	ABC transporter signature motif; other site
634456006860	Walker B; other site
634456006861	D-loop; other site
634456006862	H-loop/switch region; other site
634456006863	DL-methionine transporter substrate-binding subunit; Provisional; Region: metQ; PRK11063
634456006864	NLPA lipoprotein; Region: Lipoprotein_9; pfam03180
634456006865	FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277
634456006866	FAD binding domain; Region: FAD_binding_4; pfam01565
634456006867	siroheme synthase; Provisional; Region: cysG; PRK10637
634456006868	Putative NAD(P)-binding; Region: NAD_binding_7; pfam13241
634456006869	Sirohaem synthase dimerisation region; Region: CysG_dimeriser; pfam10414
634456006870	Uroporphyrin-III C-methyltransferase (S-Adenosyl-L-methionine:uroporphyrinogen III methyltransferase, SUMT); Region: SUMT; cd11642
634456006871	active site
634456006872	SAM binding site [chemical binding]; other site
634456006873	homodimer interface [polypeptide binding]; other site
634456006874	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cd00312
634456006875	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
634456006876	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
634456006877	Winged helix DNA-binding domain; Region: HTH_27; pfam13463
634456006878	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases [Translation, ribosomal structure and biogenesis]; Region: GatA; COG0154
634456006879	Amidase; Region: Amidase; cl11426
634456006880	Flavin reductase like domain; Region: Flavin_Reduct; smart00903
634456006881	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cl00214
634456006882	intersubunit interface [polypeptide binding]; other site
634456006883	active site
634456006884	Zn2+ binding site [ion binding]; other site
634456006885	2-dehydropantoate 2-reductase; Reviewed; Region: PRK06522
634456006886	Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558
634456006887	Ketopantoate reductase PanE/ApbA C terminal; Region: ApbA_C; pfam08546
634456006888	Phthalate dioxygenase reductase (PDR) is an FMN-dependent reductase that mediates electron transfer from NADH to FMN to an iron sulfur cluster. PDR has an an N-terminal  ferrredoxin reductase (FNR)-like NAD(H) binding domain and a C-terminal iron-sulfur; Region: PDR_like; cd06185
634456006889	Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 [Energy production and conversion]; Region: Hmp; COG1018
634456006890	FMN-binding pocket [chemical binding]; other site
634456006891	flavin binding motif; other site
634456006892	phosphate binding motif [ion binding]; other site
634456006893	beta-alpha-beta structure motif; other site
634456006894	NAD binding pocket [chemical binding]; other site
634456006895	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
634456006896	catalytic loop [active]
634456006897	iron binding site [ion binding]; other site
634456006898	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557
634456006899	classical (c) SDRs; Region: SDR_c; cd05233
634456006900	NAD(P) binding site [chemical binding]; other site
634456006901	active site
634456006902	Nuclear transport factor 2 (NTF2-like) superfamily. This family includes members of the NTF2 family, Delta-5-3-ketosteroid isomerases, Scytalone Dehydratases, and the beta subunit of Ring hydroxylating dioxygenases. This family is a classic example of...; Region: NTF2_like; cl09109
634456006903	Rieske non-heme iron oxygenase (RO) family, N-terminal Rieske domain of the oxygenase alpha subunit; The RO family comprise a large class of aromatic ring-hydroxylating dioxygenases found predominantly in microorganisms. These enzymes enable...; Region: Rieske_RO_Alpha_N; cd03469
634456006904	[2Fe-2S] cluster binding site [ion binding]; other site
634456006905	C-terminal catalytic domain of the oxygenase alpha subunit of Pseudomonas resinovorans strain CA10 anthranilate 1,2-dioxygenase and related aromatic ring hydroxylating dioxygenases; Region: RHO_alpha_C_AntDO-like; cd08879
634456006906	putative alpha subunit interface [polypeptide binding]; other site
634456006907	putative active site [active]
634456006908	putative substrate binding site [chemical binding]; other site
634456006909	Fe binding site [ion binding]; other site
634456006910	Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960
634456006911	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
634456006912	active site
634456006913	Carbohydrate-selective porin, OprB family; Region: OprB; cl17816
634456006914	NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961
634456006915	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
634456006916	NAD(P) binding site [chemical binding]; other site
634456006917	catalytic residues [active]
634456006918	PQQ-dependent dehydrogenase, methanol/ethanol family; Region: PQQ_enz_alc_DH; TIGR03075
634456006919	PQQ_like domain of the quinohemoprotein alcohol dehydrogenase (type II); Region: PQQ_ADH_II; cd10279
634456006920	Trp docking motif [polypeptide binding]; other site
634456006921	cytochrome domain interface [polypeptide binding]; other site
634456006922	active site
634456006923	Cytochrome C oxidase, cbb3-type, subunit III; Region: Cytochrome_CBB3; pfam13442
634456006924	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
634456006925	putative substrate translocation pore; other site
634456006926	SnoaL-like domain; Region: SnoaL_4; pfam13577
634456006927	Transcriptional regulator [Transcription]; Region: LysR; COG0583
634456006928	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
634456006929	The C-terminal substrate-binding domain of putative LysR-type transcriptional regulator PAO1-like, a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_PAO1_like; cd08412
634456006930	putative substrate binding pocket [chemical binding]; other site
634456006931	dimerization interface [polypeptide binding]; other site
634456006932	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
634456006933	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
634456006934	dimer interface [polypeptide binding]; other site
634456006935	conserved gate region; other site
634456006936	putative PBP binding loops; other site
634456006937	ABC-ATPase subunit interface; other site
634456006938	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
634456006939	ABC-ATPase subunit interface; other site
634456006940	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
634456006941	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
634456006942	Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; pfam13340
634456006943	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cl00427
634456006944	Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416
634456006945	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
634456006946	ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842
634456006947	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
634456006948	Walker A/P-loop; other site
634456006949	ATP binding site [chemical binding]; other site
634456006950	Q-loop/lid; other site
634456006951	ABC transporter signature motif; other site
634456006952	Walker B; other site
634456006953	D-loop; other site
634456006954	H-loop/switch region; other site
634456006955	TOBE domain; Region: TOBE_2; pfam08402
634456006956	gamma-aminobutyraldehyde dehydrogenase; Provisional; Region: PRK13473
634456006957	Escherichia coli NAD+-dependent gamma-aminobutyraldehyde dehydrogenase YdcW-like; Region: ALDH_ABALDH-YdcW; cd07092
634456006958	tetrameric interface [polypeptide binding]; other site
634456006959	NAD binding site [chemical binding]; other site
634456006960	catalytic residues [active]
634456006961	substrate binding site [chemical binding]; other site
634456006962	permease, urea carboxylase system; Region: ureacarb_perm; TIGR03428
634456006963	permease, urea carboxylase system; Region: ureacarb_perm; TIGR03428
634456006964	Outer membrane protein family (DUF1597); Region: DUF1597; pfam07642
634456006965	Fe(II)-dependent oxygenase superfamily protein; Provisional; Region: PRK05467
634456006966	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
634456006967	Sel1-like repeats; Region: SEL1; smart00671
634456006968	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
634456006969	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
634456006970	N-terminal plug; other site
634456006971	ligand-binding site [chemical binding]; other site
634456006972	MotA/TolQ/ExbB proton channel family; Region: MotA_ExbB; cl00568
634456006973	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
634456006974	Biopolymer transport protein ExbD/TolR; Region: ExbD; cl00537
634456006975	Periplasmic protein TonB, links inner and outer membranes [Cell envelope biogenesis, outer membrane]; Region: TonB; COG0810
634456006976	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
634456006977	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
634456006978	Transcriptional regulator [Transcription]; Region: LysR; COG0583
634456006979	LysR substrate binding domain; Region: LysR_substrate; pfam03466
634456006980	dimerization interface [polypeptide binding]; other site
634456006981	Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit [Inorganic ion transport and metabolism / General function prediction only]; Region: HcaE; COG4638
634456006982	Rieske non-heme iron oxygenase (RO) family, N-terminal Rieske domain of the oxygenase alpha subunit; The RO family comprise a large class of aromatic ring-hydroxylating dioxygenases found predominantly in microorganisms. These enzymes enable...; Region: Rieske_RO_Alpha_N; cd03469
634456006983	[2Fe-2S] cluster binding site [ion binding]; other site
634456006984	START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC (SRPBCC) ligand-binding domain superfamily; Region: SRPBCC; cl14643
634456006985	hydrophobic ligand binding site; other site
634456006986	C4-dicarboxylate transporter DctA; Reviewed; Region: PRK01663
634456006987	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
634456006988	Carbohydrate-selective porin, OprB family; Region: OprB; pfam04966
634456006989	Uncharacterized protein conserved in bacteria (DUF2147); Region: DUF2147; pfam09917
634456006990	Membrane bound FAD containing D-sorbitol dehydrogenase; Region: FAD-SLDH; pfam12318
634456006991	Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism]; Region: BetA; COG2303
634456006992	GMC oxidoreductase; Region: GMC_oxred_C; pfam05199
634456006993	Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010
634456006994	Cytochrome C oxidase, cbb3-type, subunit III; Region: Cytochrome_CBB3; pfam13442
634456006995	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
634456006996	Mitochondrial succinate-semialdehyde dehydrogenase and ALDH family members 5A1 and 5F1-like; Region: ALDH_F5_SSADH_GabD; cd07103
634456006997	tetramerization interface [polypeptide binding]; other site
634456006998	NAD(P) binding site [chemical binding]; other site
634456006999	catalytic residues [active]
634456007000	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
634456007001	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
634456007002	putative substrate translocation pore; other site
634456007003	Adenosylcobinamide kinase / adenosylcobinamide phosphate guanyltransferase (CobU). CobU is bifunctional cobalbumin biosynthesis enzymes which display adenosylcobinamide kinase and adenosylcobinamide phosphate guanyltransferase activity. This enzyme is a...; Region: CobU; cd00544
634456007004	homotrimer interface [polypeptide binding]; other site
634456007005	Walker A motif; other site
634456007006	GTP binding site [chemical binding]; other site
634456007007	Walker B motif; other site
634456007008	Phosphoribosyltransferase; Region: DBI_PRT; pfam02277
634456007009	Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase (DMB-PRT), also called CobT; Region: DMB-PRT_CobT; cd02439
634456007010	putative dimer interface [polypeptide binding]; other site
634456007011	active site pocket [active]
634456007012	putative cataytic base [active]
634456007013	cobalamin synthase; Reviewed; Region: cobS; PRK00235
634456007014	L-threonine-O-3-phosphate decarboxylase; Region: L_thr_O3P_dcar; TIGR01140
634456007015	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
634456007016	pyridoxal 5'-phosphate binding site [chemical binding]; other site
634456007017	homodimer interface [polypeptide binding]; other site
634456007018	catalytic residue [active]
634456007019	CobD/Cbib protein; Region: CobD_Cbib; pfam03186
634456007020	Subfamily of the nitroreductase family that includes BluB protein in Rhodobacter capsulatus is involved in the conversion of cobinamide to cobalamin in Cobalamin (vitamin B12) biosynthesis. Nitroreductases typically reduce their substrates by using NAD(P)...; Region: BluB; cd02145
634456007021	putative FMN binding site [chemical binding]; other site
634456007022	cobyric acid synthase; Provisional; Region: PRK00784
634456007023	Dethiobiotin synthetase [Coenzyme metabolism]; Region: BioD; COG0132
634456007024	Type 1 glutamine amidotransferase (GATase1) domain found in Cobyric Acid Synthase (CobQ); Region: GATase1_CobQ; cd01750
634456007025	catalytic triad [active]
634456007026	Cob(I)alamin adenosyltransferase N terminal; Region: Co_AT_N; pfam12557
634456007027	ATP:corrinoid adenosyltransferase [Coenzyme metabolism]; Region: BtuR; COG2109
634456007028	ATP:corrinoid adenosyltransferase BtuR/CobO/CobP. This family consists of the BtuR, CobO, CobP proteins all of which are Cob(I)alamin (vitamin B12) adenosyltransferase, which is involved in cobalamin (vitamin B12) biosynthesis. This enzyme is a homodimer; Region: CobA_CobO_BtuR; cd00561
634456007029	homodimer interface [polypeptide binding]; other site
634456007030	Walker A motif; other site
634456007031	ATP binding site [chemical binding]; other site
634456007032	hydroxycobalamin binding site [chemical binding]; other site
634456007033	Walker B motif; other site
634456007034	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
634456007035	catalytic core [active]
634456007036	cobyrinic acid a,c-diamide synthase; Validated; Region: PRK01077
634456007037	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
634456007038	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
634456007039	Type 1 glutamine amidotransferase (GATase1) domain found in Cobyrinic Acid a,c-Diamide Synthase; Region: GATase1_CobB; cd03130
634456007040	cobaltochelatase subunit CobN; Reviewed; Region: cobN; PRK12321
634456007041	CobN subunit of cobaltochelatase, bchH and chlH subunits of magnesium chelatases, and similar proteins; Region: CobN_like; cd10150
634456007042	cobalamin biosynthesis protein CobW; Region: CobW; TIGR02475
634456007043	CobW/HypB/UreG, nucleotide-binding domain; Region: cobW; pfam02492
634456007044	Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; pfam07683
634456007045	Thioredoxin (TRX)-like [2Fe-2S] Ferredoxin (Fd) family; composed of [2Fe-2S] Fds with a TRX fold (TRX-like Fds) and proteins containing domains similar to TRX-like Fd including formate dehydrogenases, NAD-reducing hydrogenases and the subunit E of NADH:...; Region: TRX_Fd_family; cd02980
634456007046	dimer interface [polypeptide binding]; other site
634456007047	[2Fe-2S] cluster binding site [ion binding]; other site
634456007048	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
634456007049	MarR family; Region: MarR; pfam01047
634456007050	Fusaric acid resistance protein family; Region: FUSC; pfam04632
634456007051	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
634456007052	Protein of unknown function (DUF1385); Region: DUF1385; cl01595
634456007053	GPR1/FUN34/yaaH family; Region: Grp1_Fun34_YaaH; cl00685
634456007054	3-hydroxyisobutyryl-CoA hydrolase; Provisional; Region: PRK05617
634456007055	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
634456007056	substrate binding site [chemical binding]; other site
634456007057	oxyanion hole (OAH) forming residues; other site
634456007058	trimer interface [polypeptide binding]; other site
634456007059	2-enoyl-CoA Hydratase C-terminal region; Region: ECH_C; pfam13766
634456007060	Flavin Reductases; Region: FlaRed; cl00801
634456007061	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
634456007062	dimer interface [polypeptide binding]; other site
634456007063	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cl00462
634456007064	putative PBP binding regions; other site
634456007065	ABC-ATPase subunit  interface; other site
634456007066	ABC-type Mn/Zn transport systems, ATPase component [Inorganic ion transport and metabolism]; Region: ZnuC; COG1121
634456007067	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
634456007068	Walker A/P-loop; other site
634456007069	ATP binding site [chemical binding]; other site
634456007070	Q-loop/lid; other site
634456007071	ABC transporter signature motif; other site
634456007072	Walker B; other site
634456007073	D-loop; other site
634456007074	H-loop/switch region; other site
634456007075	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
634456007076	Periplasmic solute binding protein family; Region: SBP_bac_9; pfam01297
634456007077	intersubunit interface [polypeptide binding]; other site
634456007078	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
634456007079	metal binding site 2 [ion binding]; metal-binding site
634456007080	putative DNA binding helix; other site
634456007081	metal binding site 1 [ion binding]; metal-binding site
634456007082	dimer interface [polypeptide binding]; other site
634456007083	structural Zn2+ binding site [ion binding]; other site
634456007084	methylthioribose-1-phosphate isomerase; Reviewed; Region: mtnA; PRK05720
634456007085	S-methyl-5-thioribose-1-phosphate isomerase; Region: salvage_mtnA; TIGR00512
634456007086	This CD includes cysteinyl-tRNA(Pro) deacylases from Haemophilus influenzae and Escherichia coli and other related bacterial proteins. These trans-acting, single-domain proteins are homologs of ProX and also the cis-acting prolyl-tRNA synthetase (ProRS)...; Region: YbaK_deacylase; cd00002
634456007087	putative deacylase active site [active]
634456007088	Uncharacterized protein conserved in bacteria (DUF2272); Region: DUF2272; pfam10030
634456007089	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
634456007090	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
634456007091	dimer interface [polypeptide binding]; other site
634456007092	pyridoxal 5'-phosphate binding site [chemical binding]; other site
634456007093	catalytic residue [active]
634456007094	GMP synthase; Reviewed; Region: guaA; PRK00074
634456007095	Type 1 glutamine amidotransferase (GATase1) domain found in GMP synthetase; Region: GATase1_GMP_Synthase; cd01742
634456007096	AMP/PPi binding site [chemical binding]; other site
634456007097	candidate oxyanion hole; other site
634456007098	catalytic triad [active]
634456007099	potential glutamine specificity residues [chemical binding]; other site
634456007100	The C-terminal domain of GMP synthetase. It contains two subdomains; the ATP pyrophosphatase domain which closes to the N-termial and the dimerization domain at C-terminal end. The ATP-PPase is a twisted, five-stranded parallel beta-sheet sandwiched...; Region: GMP_synthase_C; cd01997
634456007101	ATP Binding subdomain [chemical binding]; other site
634456007102	Ligand Binding sites [chemical binding]; other site
634456007103	Dimerization subdomain; other site
634456007104	multiple promoter invertase; Provisional; Region: mpi; PRK13413
634456007105	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
634456007106	catalytic residues [active]
634456007107	catalytic nucleophile [active]
634456007108	Presynaptic Site I dimer interface [polypeptide binding]; other site
634456007109	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
634456007110	Synaptic Flat tetramer interface [polypeptide binding]; other site
634456007111	Synaptic Site I dimer interface [polypeptide binding]; other site
634456007112	DNA binding site [nucleotide binding]
634456007113	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
634456007114	DNA-binding interface [nucleotide binding]; DNA binding site
634456007115	Domain of unknown function (DUF927); Region: DUF927; pfam06048
634456007116	Toprim domain; Region: Toprim_3; pfam13362
634456007117	Helix-turn-helix domain; Region: HTH_17; pfam12728
634456007118	Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; pfam13340
634456007119	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
634456007120	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
634456007121	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
634456007122	salt bridge; other site
634456007123	non-specific DNA binding site [nucleotide binding]; other site
634456007124	sequence-specific DNA binding site [nucleotide binding]; other site
634456007125	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
634456007126	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
634456007127	Domain of unknown function (DUF4145); Region: DUF4145; pfam13643
634456007128	Helix-Turn-Helix DNA binding domain of transcription regulators from the MerR superfamily; Region: HTH_MerR-SF; cl02600
634456007129	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
634456007130	DNA binding residues [nucleotide binding]
634456007131	HNH endonuclease; Region: HNH_2; pfam13391
634456007132	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
634456007133	active site
634456007134	DNA binding site [nucleotide binding]
634456007135	Int/Topo IB signature motif; other site
634456007136	MFS transporter, sugar porter (SP) family; Region: SP; TIGR00879
634456007137	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
634456007138	putative substrate translocation pore; other site
634456007139	Phage shock protein B; Region: PspB; cl05946
634456007140	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
634456007141	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
634456007142	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
634456007143	N-acetyl-D-glucosamine binding site [chemical binding]; other site
634456007144	catalytic residue [active]
634456007145	L-lactate permease [Energy production and conversion]; Region: LldP; COG1620
634456007146	L-lactate permease; Region: Lactate_perm; cl00701
634456007147	Uncharacterized conserved protein [Function unknown]; Region: COG1359
634456007148	ADP-L-glycero-D-mannoheptose 6-epimerase (GME), extended (e) SDRs; Region: ADP_GME_SDR_e; cd05248
634456007149	ADP-L-glycero-D-manno-heptose-6-epimerase; Region: heptose_epim; TIGR02197
634456007150	NADP binding site [chemical binding]; other site
634456007151	homopentamer interface [polypeptide binding]; other site
634456007152	substrate binding site [chemical binding]; other site
634456007153	active site
634456007154	prolipoprotein diacylglyceryl transferase; Reviewed; Region: PRK00052
634456007155	Putative S-adenosyl-L-methionine-dependent methyltransferase; Region: Methyltransf_28; pfam02636
634456007156	Multicopper polyphenol oxidase (laccase) [Secondary metabolites biosynthesis, transport and catabolism]; Region: yfiH; COG1496
634456007157	Multi-copper polyphenol oxidoreductase laccase; Region: Cu-oxidase_4; pfam02578
634456007158	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
634456007159	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
634456007160	N-acetyl-D-glucosamine binding site [chemical binding]; other site
634456007161	catalytic residue [active]
634456007162	Cell division protein [Cell division and chromosome partitioning]; Region: FtsN; COG3087
634456007163	Sporulation related domain; Region: SPOR; pfam05036
634456007164	ABC-type polysaccharide/polyol phosphate export systems, permease component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: TagG; COG1682
634456007165	ABC-2 type transporter; Region: ABC2_membrane; cl17235
634456007166	ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: TagH; COG1134
634456007167	ATP-binding cassette component of polysaccharide transport system; Region: ABC_KpsT_Wzt; cd03220
634456007168	Walker A/P-loop; other site
634456007169	ATP binding site [chemical binding]; other site
634456007170	Q-loop/lid; other site
634456007171	ABC transporter signature motif; other site
634456007172	Walker B; other site
634456007173	D-loop; other site
634456007174	H-loop/switch region; other site
634456007175	Uncharacterized conserved protein [Function unknown]; Region: COG1742
634456007176	CorA-like Mg2+ transporter protein; Region: CorA; pfam01544
634456007177	Uncharacterized bacterial subgroup of the Salmonella typhimurium Zn2+ transporter ZntB-like subfamily; Region: ZntB_u1; cd12834
634456007178	Cl binding site [ion binding]; other site
634456007179	oligomer interface [polypeptide binding]; other site
634456007180	Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase [Amino acid transport and metabolism]; Region: HisC; COG0079
634456007181	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
634456007182	pyridoxal 5'-phosphate binding site [chemical binding]; other site
634456007183	homodimer interface [polypeptide binding]; other site
634456007184	catalytic residue [active]
634456007185	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
634456007186	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
634456007187	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
634456007188	Transketolase [Carbohydrate transport and metabolism]; Region: TktA; COG0021
634456007189	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
634456007190	TPP-binding site [chemical binding]; other site
634456007191	dimer interface [polypeptide binding]; other site
634456007192	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
634456007193	PYR/PP interface [polypeptide binding]; other site
634456007194	dimer interface [polypeptide binding]; other site
634456007195	TPP binding site [chemical binding]; other site
634456007196	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
634456007197	bifunctional transaldolase/phosoglucose isomerase; Validated; Region: PRK09533
634456007198	Transaldolase-like proteins from plants and bacteria; Region: Transaldolase_like; cd00955
634456007199	putative active site [active]
634456007200	catalytic residue [active]
634456007201	SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars; Region: SIS; cl00389
634456007202	SIS_TAL_PGI: Transaldolase (TAL)/ Phosphoglucose isomerase (PGI). This group represents the SIS (Sugar ISomerase) PGI domain, of a multifunctional protein (TAL-PGI ) having both TAL and PGI activities. TAL_PGI contains an N-terminal TAL domain and a...; Region: SIS_TAL_PGI; cd05798
634456007203	Predicted 6-phosphogluconate dehydrogenase [Carbohydrate transport and metabolism]; Region: Gnd; COG1023
634456007204	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
634456007205	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
634456007206	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
634456007207	active site
634456007208	motif I; other site
634456007209	motif II; other site
634456007210	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
634456007211	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
634456007212	6PGL: 6-Phosphogluconolactonase (6PGL) subfamily; 6PGL catalyzes the second step of the oxidative phase of the pentose phosphate pathway, the hydrolyzation of 6-phosphoglucono-1,5-lactone (delta form) to 6-phosphogluconate. 6PGL is thought to guard...; Region: 6PGL; cd01400
634456007213	putative active site [active]
634456007214	RPI_A: Ribose 5-phosphate isomerase type A (RPI_A) subfamily; RPI catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate, the first step of the non-oxidative branch of the pentose phosphate pathway. This reaction leads to the...; Region: RPI_A; cd01398
634456007215	tetramer (dimer of dimers) interface [polypeptide binding]; other site
634456007216	active site
634456007217	dimer interface [polypeptide binding]; other site
634456007218	Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting product gluconate-6-phoshate is an important precursor of gluconate metabolism. GntK acts as a dimmer composed of two identical subunits; Region: GntK; cd02021
634456007219	AAA domain; Region: AAA_33; pfam13671
634456007220	ATP-binding site [chemical binding]; other site
634456007221	Gluconate-6-phosphate binding site [chemical binding]; other site
634456007222	ABC-type hemin transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: ChuT; COG4558
634456007223	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
634456007224	intersubunit interface [polypeptide binding]; other site
634456007225	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
634456007226	CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This...; Region: Voltage_gated_ClC; cd00400
634456007227	Cl- selectivity filter; other site
634456007228	Cl- binding residues [ion binding]; other site
634456007229	pore gating glutamate residue; other site
634456007230	dimer interface [polypeptide binding]; other site
634456007231	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cd02205
634456007232	putative NAD(P)H quinone oxidoreductase, PIG3 family; Region: quinone_pig3; TIGR02824
634456007233	PIG3 p53-inducible quinone oxidoreductase; Region: p53_inducible_oxidoreductase; cd05276
634456007234	NAD(P) binding site [chemical binding]; other site
634456007235	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, YBL036c-like proteins; Region: PLPDE_III_YBL036c_like; cd00635
634456007236	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
634456007237	catalytic residue [active]
634456007238	K+ transporter [Inorganic ion transport and metabolism]; Region: Kup; COG3158
634456007239	potassium uptake protein; Region: kup; TIGR00794
634456007240	coproporphyrinogen III oxidase; Provisional; Region: PRK09057
634456007241	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
634456007242	FeS/SAM binding site; other site
634456007243	HemN C-terminal domain; Region: HemN_C; pfam06969
634456007244	Protein of unknown function (DUF1489); Region: DUF1489; pfam07370
634456007245	urea ABC transporter, ATP-binding protein UrtE; Region: urea_trans_UrtE; TIGR03410
634456007246	ATP-binding cassette domain of branched-chain amino acid transporter; Region: ABC_TM1139_LivF_branched; cd03224
634456007247	Walker A/P-loop; other site
634456007248	ATP binding site [chemical binding]; other site
634456007249	Q-loop/lid; other site
634456007250	ABC transporter signature motif; other site
634456007251	Walker B; other site
634456007252	D-loop; other site
634456007253	H-loop/switch region; other site
634456007254	urea ABC transporter, ATP-binding protein UrtD; Region: urea_trans_UrtD; TIGR03411
634456007255	ATP-binding cassette component of branched chain amino acids transport system; Region: ABC_Mj1267_LivG_branched; cd03219
634456007256	Walker A/P-loop; other site
634456007257	ATP binding site [chemical binding]; other site
634456007258	Q-loop/lid; other site
634456007259	ABC transporter signature motif; other site
634456007260	Walker B; other site
634456007261	D-loop; other site
634456007262	H-loop/switch region; other site
634456007263	ABC-type branched-chain amino acid transport system, permease component [Amino acid transport and metabolism]; Region: LivM; COG4177
634456007264	Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivM_like; cd06581
634456007265	TM-ABC transporter signature motif; other site
634456007266	HEAT repeats; Region: HEAT_2; pfam13646
634456007267	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
634456007268	Transmembrane subunit (TM) of Escherichia coli LivH and related proteins. LivH is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivH_like; cd06582
634456007269	TM-ABC transporter signature motif; other site
634456007270	Periplasmic binding protein; Region: Peripla_BP_6; pfam13458
634456007271	Periplasmic component (FmdD) of an active transport system for short-chain amides and urea (FmdDEF); Region: PBP1_FmdD_like; cd06355
634456007272	putative ligand binding site [chemical binding]; other site
634456007273	Solute carrier families 5 and 6-like; solute binding domain; Region: SLC5-6-like_sbd; cl00456
634456007274	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
634456007275	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
634456007276	dimer interface [polypeptide binding]; other site
634456007277	phosphorylation site [posttranslational modification]
634456007278	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
634456007279	ATP binding site [chemical binding]; other site
634456007280	Mg2+ binding site [ion binding]; other site
634456007281	G-X-G motif; other site
634456007282	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
634456007283	Response regulator receiver domain; Region: Response_reg; pfam00072
634456007284	active site
634456007285	phosphorylation site [posttranslational modification]
634456007286	intermolecular recognition site; other site
634456007287	dimerization interface [polypeptide binding]; other site
634456007288	Response regulator receiver domain; Region: Response_reg; pfam00072
634456007289	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
634456007290	active site
634456007291	phosphorylation site [posttranslational modification]
634456007292	intermolecular recognition site; other site
634456007293	dimerization interface [polypeptide binding]; other site
634456007294	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
634456007295	DNA binding residues [nucleotide binding]
634456007296	HTH-like domain; Region: HTH_21; pfam13276
634456007297	Integrase core domain; Region: rve; pfam00665
634456007298	Transposase DDE domain group 1; Region: DDE_Tnp_1_4; pfam13701
634456007299	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
634456007300	Urease accessory protein UreF [Posttranslational modification, protein turnover, chaperones]; Region: UreF; COG0830
634456007301	UreF; Region: UreF; pfam01730
634456007302	Urease accessory protein UreE [Posttranslational modification, protein turnover, chaperones]; Region: UreE; COG2371
634456007303	UreE urease accessory protein. UreE is a metallochaperone assisting the insertion of a Ni2+ ion in the active site of urease, an important step in the in vivo assembly of urease, an enzyme that hydrolyses urea into ammonia and carbamic acid. The...; Region: UreE; cd00571
634456007304	dimer interface [polypeptide binding]; other site
634456007305	catalytic residues [active]
634456007306	urease subunit alpha; Reviewed; Region: ureC; PRK13207
634456007307	Urease alpha-subunit; Urease is a nickel-dependent metalloenzyme that catalyzes the hydrolysis of urea to form ammonia and carbon dioxide. Nickel-dependent ureases are found in bacteria, fungi and plants. Their primary role is to allow the use of...; Region: Urease_alpha; cd00375
634456007308	subunit interactions [polypeptide binding]; other site
634456007309	active site
634456007310	flap region; other site
634456007311	Urease beta-subunit; Urease is a nickel-dependent metalloenzyme that catalyzes the hydrolysis of urea to form ammonia and carbon dioxide. Nickel-dependent ureases are found in bacteria, archaea, fungi and plants. Their primary role is to allow the use of...; Region: Urease_beta; cd00407
634456007312	alpha-beta subunit interface [polypeptide binding]; other site
634456007313	Urease gamma-subunit; Urease is a nickel-dependent metalloenzyme that catalyzes the hydrolysis of urea to form ammonia and carbon dioxide. Nickel-dependent ureases are found in bacteria, archaea, fungi and plants. Their primary role is to allow the use...; Region: Urease_gamma; cd00390
634456007314	alpha-gamma subunit interface [polypeptide binding]; other site
634456007315	beta-gamma subunit interface [polypeptide binding]; other site
634456007316	UreD urease accessory protein; Region: UreD; pfam01774
634456007317	High-affinity nickel-transport protein; Region: NicO; cl00964
634456007318	Pyruvate decarboxylase and related thiamine pyrophosphate-requiring enzymes [Carbohydrate transport and metabolism / Coenzyme metabolism / General function prediction only]; Region: COG3961
634456007319	Pyrimidine (PYR) binding domain of pyruvate decarboxylase (PDC), indolepyruvate decarboxylase (IPDC) and related proteins; Region: TPP_PYR_PDC_IPDC_like; cd07038
634456007320	dimer interface [polypeptide binding]; other site
634456007321	PYR/PP interface [polypeptide binding]; other site
634456007322	TPP binding site [chemical binding]; other site
634456007323	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
634456007324	Thiamine pyrophosphate (TPP) family, PDC_IPDC subfamily, TPP-binding module; composed of proteins similar to pyruvate decarboxylase (PDC) and indolepyruvate decarboxylase (IPDC). PDC, a key enzyme in alcoholic fermentation, catalyzes the conversion of...; Region: TPP_PDC_IPDC; cd02005
634456007325	TPP-binding site [chemical binding]; other site
634456007326	dimer interface [polypeptide binding]; other site
634456007327	Broad specificity phosphatase PhoE and related phosphatases [General function prediction only]; Region: phoE; COG0406
634456007328	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
634456007329	Domain of unknown function (DUF4105); Region: DUF4105; pfam13387
634456007330	Bacterioferritin (cytochrome b1) [Inorganic ion transport and metabolism]; Region: Bfr; COG2193
634456007331	Bacterioferritin, ferritin-like diiron-binding domain; Region: Bacterioferritin; cd00907
634456007332	heme binding site [chemical binding]; other site
634456007333	ferroxidase pore; other site
634456007334	ferroxidase diiron center [ion binding]; other site
634456007335	Arsenate Reductase (ArsC) family, Yffb subfamily; Yffb is an uncharacterized bacterial protein encoded by the yffb gene, related to the thioredoxin-fold arsenic reductases, ArsC. The structure of Yffb and the conservation of the catalytic cysteine...; Region: ArsC_Yffb; cd03035
634456007336	ArsC family; Region: ArsC; pfam03960
634456007337	putative catalytic residues [active]
634456007338	HIT family: HIT (Histidine triad) proteins, named for a motif related to the sequence HxHxH/Qxx (x, a hydrophobic amino acid), are a superfamily of nucleotide hydrolases and transferases, which act on the alpha-phosphate of ribonucleotides. On the basis...; Region: HIT_like; cl00228
634456007339	Methyladenine glycosylase; Region: Adenine_glyco; pfam03352
634456007340	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
634456007341	dimerization interface [polypeptide binding]; other site
634456007342	putative DNA binding site [nucleotide binding]; other site
634456007343	putative Zn2+ binding site [ion binding]; other site
634456007344	peroxiredoxin; Provisional; Region: PRK13189
634456007345	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
634456007346	Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491
634456007347	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
634456007348	Sulfate permease and related transporters (MFS superfamily) [Inorganic ion transport and metabolism]; Region: SUL1; COG0659
634456007349	Sulfate transporter N-terminal domain with GLY motif; Region: Sulfate_tra_GLY; pfam13792
634456007350	Sulfate transporter family; Region: Sulfate_transp; pfam00916
634456007351	Sulphate Transporter and Anti-Sigma factor antagonist domain of SulP-like sulfate transporters, plays a role in the function and regulation of the transport activity, proposed general NTP binding function; Region: STAS_SulP_like_sulfate_transporter; cd07042
634456007352	Arsenate Reductase (ArsC) family, ArsC subfamily; arsenic reductases similar to that encoded by arsC on the R733 plasmid of Escherichia coli. E. coli ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], the first step in the...; Region: ArsC_ArsC; cd03034
634456007353	catalytic residues [active]
634456007354	Transposase DDE domain group 1; Region: DDE_Tnp_1_4; pfam13701
634456007355	Pirin-related protein [General function prediction only]; Region: COG1741
634456007356	efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family; Region: outer_NodT; TIGR01845
634456007357	efflux pump membrane protein (multidrug resistance protein A); Region: 8a0101; TIGR00998
634456007358	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
634456007359	HlyD family secretion protein; Region: HlyD_3; pfam13437
634456007360	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
634456007361	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
634456007362	Transcriptional regulator [Transcription]; Region: LysR; COG0583
634456007363	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
634456007364	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator similar to DntR, which is involved in the catabolism of dinitrotoluene; contains the type 2 periplasmic binding fold; Region: PBP2_DntR_like_1; cd08460
634456007365	putative dimerization interface [polypeptide binding]; other site
634456007366	Transposase DDE domain group 1; Region: DDE_Tnp_1_4; pfam13701
634456007367	Carbohydrate-selective porin, OprB family; Region: OprB; pfam04966
634456007368	4-hydroxyphenylacetate permease; Region: HpaX; TIGR02332
634456007369	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
634456007370	putative substrate translocation pore; other site
634456007371	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
634456007372	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
634456007373	Asp/Glu/Hydantoin racemase; Region: Asp_Glu_race; cl00518
634456007374	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
634456007375	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cl00220
634456007376	Isochorismatase family; Region: Isochorismatase; pfam00857
634456007377	catalytic triad [active]
634456007378	conserved cis-peptide bond; other site
634456007379	Leucyl aminopeptidase (aminopeptidase T) [Amino acid transport and metabolism]; Region: AmpS; COG2309
634456007380	Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738
634456007381	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Region: Ald_Xan_dh_C; smart01008
634456007382	Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738
634456007383	Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs [Energy production and conversion]; Region: CoxL; COG1529
634456007384	Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738
634456007385	Cytochrome c; Region: Cytochrom_C; pfam00034
634456007386	Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010
634456007387	Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010
634456007388	Cytochrome c; Region: Cytochrom_C; pfam00034
634456007389	Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs [Energy production and conversion]; Region: CoxS; COG2080
634456007390	Ferredoxin reductase (FNR), an FAD and NAD(P) binding protein, was intially identified as a chloroplast reductase activity, catalyzing the electron transfer from reduced iron-sulfur protein ferredoxin to NADP+ as the final step in the electron transport...; Region: FNR_like; cl06868
634456007391	[2Fe-2S] binding domain; Region: Fer2_2; pfam01799
634456007392	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
634456007393	Transcriptional regulators [Transcription]; Region: MarR; COG1846
634456007394	MarR family; Region: MarR_2; pfam12802
634456007395	Transposase DDE domain group 1; Region: DDE_Tnp_1_4; pfam13701
634456007396	Peptidase S8 family domain in Subtilisin-like proteins; Region: Peptidases_S8_Subtilisin_like_2; cd04847
634456007397	active site
634456007398	catalytic triad [active]
634456007399	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
634456007400	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
634456007401	Walker A motif; other site
634456007402	ATP binding site [chemical binding]; other site
634456007403	Walker B motif; other site
634456007404	arginine finger; other site
634456007405	Bacterial conjugation TrbI-like protein; Region: TrbI; pfam03743
634456007406	putative transposase OrfB; Reviewed; Region: PHA02517
634456007407	HTH-like domain; Region: HTH_21; pfam13276
634456007408	Integrase core domain; Region: rve; pfam00665
634456007409	Integrase core domain; Region: rve_3; pfam13683
634456007410	Transposase; Region: HTH_Tnp_1; cl17663
634456007411	VirB9/CagX/TrbG, a component of the type IV secretion system; Region: VirB9_CagX_TrbG; cl11423
634456007412	conjugal transfer protein TrbF; Provisional; Region: PRK13872
634456007413	conjugal transfer protein TrbL; Provisional; Region: PRK13875
634456007414	TrbL/VirB6 plasmid conjugal transfer protein; Region: TrbL; cl01503
634456007415	Transposase DDE domain group 1; Region: DDE_Tnp_1_4; pfam13701
634456007416	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
634456007417	Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or C-terminal to the catalytic domain. These enzymes perform site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining...; Region: Ser_Recombinase; cd00338
634456007418	catalytic residues [active]
634456007419	catalytic nucleophile [active]
634456007420	Recombinase; Region: Recombinase; pfam07508
634456007421	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
634456007422	non-specific DNA binding site [nucleotide binding]; other site
634456007423	salt bridge; other site
634456007424	sequence-specific DNA binding site [nucleotide binding]; other site
634456007425	chromosome segregation protein SMC, common bacterial type; Region: SMC_prok_B; TIGR02168
634456007426	Transposase DDE domain group 1; Region: DDE_Tnp_1_4; pfam13701
634456007427	putative transposase OrfB; Reviewed; Region: PHA02517
634456007428	HTH-like domain; Region: HTH_21; pfam13276
634456007429	Integrase core domain; Region: rve; pfam00665
634456007430	Integrase core domain; Region: rve_3; pfam13683
634456007431	Transposase; Region: HTH_Tnp_1; cl17663
634456007432	Uncharacterized conserved protein (DUF2285); Region: DUF2285; pfam10074
634456007433	Replication initiator protein A; Region: RPA; pfam10134
634456007434	putative transposase OrfB; Reviewed; Region: PHA02517
634456007435	HTH-like domain; Region: HTH_21; pfam13276
634456007436	Integrase core domain; Region: rve; pfam00665
634456007437	Integrase core domain; Region: rve_3; pfam13683
634456007438	Transposase DDE domain group 1; Region: DDE_Tnp_1_4; pfam13701
634456007439	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
634456007440	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
634456007441	NAD(P) binding site [chemical binding]; other site
634456007442	active site
634456007443	Uncharacterized ACR, COG1430; Region: DUF192; pfam02643
634456007444	Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491
634456007445	Protein required for attachment to host cells; Region: Host_attach; pfam10116
634456007446	Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family [Posttranslational modification, protein turnover, chaperones]; Region: XdhC; COG1975
634456007447	XdhC and CoxI family; Region: XdhC_CoxI; pfam02625
634456007448	XdhC Rossmann domain; Region: XdhC_C; pfam13478
634456007449	GT_2_like_f is a subfamily of the glycosyltransferase family 2 (GT-2) with unknown function; Region: GT_2_like_f; cd04182
634456007450	Ligand binding site; other site
634456007451	metal-binding site
634456007452	This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function.  The conserved domain is similar in structure to chorismate mutase but there is no sequence...; Region: YjgF_YER057c_UK114_like_2; cd06150
634456007453	homotrimer interaction site [polypeptide binding]; other site
634456007454	putative active site [active]
634456007455	CHAP domain; Region: CHAP; cl17642
634456007456	glycine dehydrogenase; Provisional; Region: PRK05367
634456007457	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
634456007458	tetramer interface [polypeptide binding]; other site
634456007459	pyridoxal 5'-phosphate binding site [chemical binding]; other site
634456007460	catalytic residue [active]
634456007461	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
634456007462	tetramer interface [polypeptide binding]; other site
634456007463	pyridoxal 5'-phosphate binding site [chemical binding]; other site
634456007464	catalytic residue [active]
634456007465	Glycine cleavage H-protein. Glycine cleavage H-proteins are part of the glycine cleavage system (GCS) found in bacteria, archea and the mitochondria of eukaryotes. GCS is a multienzyme complex consisting of 4 different components (P-, H-, T- and...; Region: GCS_H; cd06848
634456007466	lipoyl attachment site [posttranslational modification]; other site
634456007467	glycine cleavage system aminomethyltransferase T; Provisional; Region: gcvT; PRK13579
634456007468	Glycine cleavage T-protein C-terminal barrel domain; Region: GCV_T_C; pfam08669
634456007469	spermidine synthase; Provisional; Region: PRK00811
634456007470	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
634456007471	S-adenosylmethionine binding site [chemical binding]; other site
634456007472	S-adenosylmethionine decarboxylase proenzyme, Bacillus form; Region: SAM_DCase_Bsu; TIGR03330
634456007473	Transcriptional regulator [Transcription]; Region: LysR; COG0583
634456007474	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
634456007475	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
634456007476	putative effector binding pocket; other site
634456007477	dimerization interface [polypeptide binding]; other site
634456007478	cyclophilin: cyclophilin-type peptidylprolyl cis- trans isomerases. This family contains eukaryotic, bacterial and archeal proteins which exhibit a peptidylprolyl cis- trans isomerases activity (PPIase, Rotamase) and in addition bind the...; Region: cyclophilin; cd00317
634456007479	active site
634456007480	phosphopantetheine adenylyltransferase; Provisional; Region: coaD; PRK00168
634456007481	Phosphopantetheine adenylyltransferase; Region: PPAT; cd02163
634456007482	active site
634456007483	(T/H)XGH motif; other site
634456007484	DNA gyrase, A subunit; Region: gyrA; TIGR01063
634456007485	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
634456007486	CAP-like domain; other site
634456007487	active site
634456007488	primary dimer interface [polypeptide binding]; other site
634456007489	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
634456007490	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
634456007491	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
634456007492	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
634456007493	2-Nitropropane dioxygenase (NPD), one of the nitroalkane oxidizing enzyme families, catalyzes oxidative denitrification of nitroalkanes to their corresponding carbonyl compounds and nitrites. NDP is a member of the NAD(P)H-dependent flavin oxidoreductase...; Region: NPD_like; cd04730
634456007494	FMN binding site [chemical binding]; other site
634456007495	substrate binding site [chemical binding]; other site
634456007496	putative catalytic residue [active]
634456007497	polynucleotide phosphorylase/polyadenylase; Provisional; Region: PRK11824
634456007498	Polyribonucleotide nucleotidyltransferase, repeat 1; Region: RNase_PH_PNPase_1; cd11363
634456007499	RNase E interface [polypeptide binding]; other site
634456007500	trimer interface [polypeptide binding]; other site
634456007501	Polyribonucleotide nucleotidyltransferase, RNA binding domain; Region: PNPase; pfam03726
634456007502	Polyribonucleotide nucleotidyltransferase, repeat 2; Region: RNase_PH_PNPase_2; cd11364
634456007503	RNase E interface [polypeptide binding]; other site
634456007504	trimer interface [polypeptide binding]; other site
634456007505	active site
634456007506	Polynucleotide phosphorylase (PNPase) K homology RNA-binding domain (KH). PNPase is a polyribonucleotide nucleotidyl transferase that degrades mRNA in prokaryotes and plant chloroplasts. The C-terminal region of PNPase contains domains homologous to...; Region: PNPase_KH; cd02393
634456007507	putative nucleic acid binding region [nucleotide binding]; other site
634456007508	G-X-X-G motif; other site
634456007509	S1_PNPase: Polynucleotide phosphorylase (PNPase), ), S1-like RNA-binding domain. PNPase  is a polyribonucleotide nucleotidyl transferase that degrades mRNA. It is a trimeric multidomain protein. The C-terminus contains the S1 domain which binds ssRNA; Region: S1_PNPase; cd04472
634456007510	RNA binding site [nucleotide binding]; other site
634456007511	domain interface; other site
634456007512	Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; Region: Ribosomal_S15p_S13e; cd00353
634456007513	16S/18S rRNA binding site [nucleotide binding]; other site
634456007514	S13e-L30e interaction site [polypeptide binding]; other site
634456007515	25S rRNA binding site [nucleotide binding]; other site
634456007516	tRNA pseudouridine synthase B; Provisional; Region: truB; PRK05389
634456007517	Pseudouridine synthase, Escherichia coli TruB like; Region: PseudoU_synth_EcTruB; cd02573
634456007518	RNA binding site [nucleotide binding]; other site
634456007519	active site
634456007520	Pseudouridine synthase II TruB, C-terminal; Region: TruB-C_2; pfam09157
634456007521	Permease; Region: Permease; pfam02405
634456007522	ABC-type transport system involved in resistance to organic solvents, ATPase component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2A; COG1127
634456007523	ATP-binding cassette transport system involved in resistant to organic solvents; Region: ABC_Org_Solvent_Resistant; cd03261
634456007524	Walker A/P-loop; other site
634456007525	ATP binding site [chemical binding]; other site
634456007526	Q-loop/lid; other site
634456007527	ABC transporter signature motif; other site
634456007528	Walker B; other site
634456007529	D-loop; other site
634456007530	H-loop/switch region; other site
634456007531	mce related protein; Region: MCE; pfam02470
634456007532	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3009
634456007533	Protein of unknown function (DUF330); Region: DUF330; pfam03886
634456007534	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
634456007535	This family is most closely related to the GT1 family of glycosyltransferases. ExpC in Rhizobium meliloti has been shown to be involved in the biosynthesis of galactoglucan (exopolysaccharide II); Region: GT1_ExpC_like; cd03818
634456007536	putative ADP-binding pocket [chemical binding]; other site
634456007537	Clostridial hydrophobic W; Region: ChW; cl02763
634456007538	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
634456007539	binding surface
634456007540	TPR motif; other site
634456007541	Predicted glycosyltransferases [General function prediction only]; Region: COG1216
634456007542	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
634456007543	active site
634456007544	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
634456007545	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
634456007546	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
634456007547	Sel1-like repeats; Region: SEL1; smart00671
634456007548	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
634456007549	Sel1-like repeats; Region: SEL1; smart00671
634456007550	Sel1-like repeats; Region: SEL1; smart00671
634456007551	Sel1 repeat; Region: Sel1; cl02723
634456007552	Sel1-like repeats; Region: SEL1; smart00671
634456007553	type I secretion membrane fusion protein, HlyD family; Region: type_I_hlyD; TIGR01843
634456007554	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
634456007555	HlyD family secretion protein; Region: HlyD_3; pfam13437
634456007556	Peptidase family C39 mostly contains bacteriocin-processing endopeptidases from bacteria. The cysteine peptidases in family C39 cleave the "double-glycine" leader peptides from the precursors of various bacteriocins (mostly non-lantibiotic); Region: Peptidase_C39_like; cd02259
634456007557	putative active site [active]
634456007558	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms]; Region: SunT; COG2274
634456007559	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
634456007560	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
634456007561	Walker A/P-loop; other site
634456007562	ATP binding site [chemical binding]; other site
634456007563	Q-loop/lid; other site
634456007564	ABC transporter signature motif; other site
634456007565	Walker B; other site
634456007566	D-loop; other site
634456007567	H-loop/switch region; other site
634456007568	Methionine synthase I (cobalamin-dependent), methyltransferase domain [Amino acid transport and metabolism]; Region: MetH; COG0646
634456007569	5-methyltetrahydrofolate--homocysteine methyltransferase; Region: metH; TIGR02082
634456007570	Pterin binding enzymes. This family includes dihydropteroate synthase (DHPS) and cobalamin-dependent methyltransferases such as methyltetrahydrofolate, corrinoid iron-sulfur protein methyltransferase (MeTr) and methionine synthase (MetH).  DHPS, a...; Region: Pterin_binding; cl00219
634456007571	substrate binding pocket [chemical binding]; other site
634456007572	dimer interface [polypeptide binding]; other site
634456007573	inhibitor binding site; inhibition site
634456007574	B12 binding domain of methionine synthase. This domain binds methylcobalamin, which it uses as an intermediate methyl carrier from methyltetrahydrofolate (CH3H4folate) to homocysteine (Hcy); Region: methionine_synthase_B12_BD; cd02069
634456007575	B12 binding site [chemical binding]; other site
634456007576	cobalt ligand [ion binding]; other site
634456007577	Vitamin B12 dependent methionine synthase, activation domain; Region: Met_synt_B12; pfam02965
634456007578	Colicin V production protein; Region: Colicin_V; pfam02674
634456007579	amidophosphoribosyltransferase; Provisional; Region: PRK09123
634456007580	Glutamine amidotransferases class-II (GN-AT)_GPAT- type. This domain is found at the N-terminus of  glutamine phosphoribosylpyrophosphate (Prpp) amidotransferase (GPATase) . The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the...; Region: GPATase_N; cd00715
634456007581	active site
634456007582	tetramer interface [polypeptide binding]; other site
634456007583	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
634456007584	active site
634456007585	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3009
634456007586	Protein of unknown function (DUF330); Region: DUF330; pfam03886
634456007587	Paraquat-inducible protein B [General function prediction only]; Region: PqiB; COG3008
634456007588	mce related protein; Region: MCE; pfam02470
634456007589	mce related protein; Region: MCE; pfam02470
634456007590	mce related protein; Region: MCE; pfam02470
634456007591	Uncharacterized paraquat-inducible protein A [Function unknown]; Region: PqiA; COG2995
634456007592	Paraquat-inducible protein A; Region: PqiA; pfam04403
634456007593	Paraquat-inducible protein A; Region: PqiA; pfam04403
634456007594	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family [Cell envelope biogenesis, outer membrane]; Region: ArnT; COG1807
634456007595	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; cl17364
634456007596	dolichyl-phosphate beta-D-mannosyltransferase; Region: PLN02726
634456007597	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
634456007598	active site
634456007599	ATP synthase B/B' CF(0); Region: ATP-synt_B; cl17192
634456007600	F0F1-type ATP synthase, subunit b [Energy production and conversion]; Region: AtpF; COG0711
634456007601	ATP synthase subunit C; Region: ATP-synt_C; cl00466
634456007602	F0F1 ATP synthase subunit A; Validated; Region: PRK05815
634456007603	F0F1-type ATP synthase, subunit a [Energy production and conversion]; Region: AtpB; COG0356
634456007604	Putative F0F1-ATPase subunit (ATPase_gene1); Region: ATPase_gene1; pfam09527
634456007605	signal recognition particle-docking protein FtsY; Provisional; Region: PRK10416
634456007606	SRP54-type protein, helical bundle domain; Region: SRP54_N; pfam02881
634456007607	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
634456007608	MiaB-like tRNA modifying enzyme; Region: MiaB-like-C; TIGR01579
634456007609	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
634456007610	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
634456007611	FeS/SAM binding site; other site
634456007612	diaminopimelate epimerase; Provisional; Region: dapF; PRK00450
634456007613	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
634456007614	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
634456007615	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
634456007616	Glyoxalase I catalyzes the isomerization of the hemithioacetal, formed by a 2-oxoaldehyde and glutathione, to S-D-lactoylglutathione; Region: Glyoxalase_I; cd07233
634456007617	dimer interface [polypeptide binding]; other site
634456007618	active site
634456007619	metal binding site [ion binding]; metal-binding site
634456007620	glutathione binding site [chemical binding]; other site
634456007621	DEAD-like helicases superfamily; Region: DEXDc; smart00487
634456007622	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
634456007623	ATP binding site [chemical binding]; other site
634456007624	Mg++ binding site [ion binding]; other site
634456007625	motif III; other site
634456007626	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
634456007627	nucleotide binding region [chemical binding]; other site
634456007628	ATP-binding site [chemical binding]; other site
634456007629	RNA recognition motif in the DbpA subfamily of prokaryotic DEAD-box rRNA helicases; Region: RRM_DbpA; cd12252
634456007630	RNA binding site [nucleotide binding]; other site
634456007631	Carboxypeptidase C (cathepsin A) [Amino acid transport and metabolism]; Region: COG2939
634456007632	Serine carboxypeptidase; Region: Peptidase_S10; cl08270
634456007633	30S ribosomal protein S9; Reviewed; Region: rpsI; PRK00132
634456007634	Ribosomal protein L13.  Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392
634456007635	23S rRNA interface [nucleotide binding]; other site
634456007636	L3 interface [polypeptide binding]; other site
634456007637	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
634456007638	Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG0702
634456007639	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
634456007640	phosphate transport system regulatory protein PhoU; Region: phoU_full; TIGR02135
634456007641	PhoU domain; Region: PhoU; pfam01895
634456007642	PhoU domain; Region: PhoU; pfam01895
634456007643	phosphate transporter ATP-binding protein; Provisional; Region: pstB; PRK10744
634456007644	ATP-binding cassette domain of the phosphate transport system; Region: ABC_PstB_phosphate_transporter; cd03260
634456007645	Walker A/P-loop; other site
634456007646	ATP binding site [chemical binding]; other site
634456007647	Q-loop/lid; other site
634456007648	ABC transporter signature motif; other site
634456007649	Walker B; other site
634456007650	D-loop; other site
634456007651	H-loop/switch region; other site
634456007652	phosphate transporter permease subunit PtsA; Provisional; Region: pstA; PRK11268
634456007653	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
634456007654	dimer interface [polypeptide binding]; other site
634456007655	conserved gate region; other site
634456007656	putative PBP binding loops; other site
634456007657	ABC-ATPase subunit interface; other site
634456007658	ABC-type phosphate transport system, permease component [Inorganic ion transport and metabolism]; Region: PstC; COG0573
634456007659	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
634456007660	dimer interface [polypeptide binding]; other site
634456007661	conserved gate region; other site
634456007662	putative PBP binding loops; other site
634456007663	ABC-ATPase subunit interface; other site
634456007664	dihydroxy-acid dehydratase; Provisional; Region: PRK12448
634456007665	Quinone oxidoreductase (QOR); Region: QOR2; cd05286
634456007666	quinone oxidoreductase, NADPH-dependent; Provisional; Region: PRK10754
634456007667	NADP binding site [chemical binding]; other site
634456007668	dimer interface [polypeptide binding]; other site
634456007669	Predicted membrane protein [Function unknown]; Region: COG1289
634456007670	Bacterial protein of unknown function (DUF939); Region: DUF939; pfam06081
634456007671	periplasmic serine protease, Do/DeqQ family; Region: degP_htrA_DO; TIGR02037
634456007672	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
634456007673	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
634456007674	protein binding site [polypeptide binding]; other site
634456007675	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
634456007676	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cd00229
634456007677	active site
634456007678	catalytic triad [active]
634456007679	oxyanion hole [active]
634456007680	OpgC protein; Region: OpgC_C; pfam10129
634456007681	Acyltransferase family; Region: Acyl_transf_3; pfam01757
634456007682	antiporter inner membrane protein; Provisional; Region: PRK11670
634456007683	Domain of unknown function DUF59; Region: DUF59; pfam01883
634456007684	MRP (Multiple Resistance and pH adaptation) is a homologue of the Fer4_NifH superfamily. Like the other members of the superfamily, MRP contains a ATP-binding domain at the N-termini. It is found in bacteria as a membrane-spanning protein and functions...; Region: MRP-like; cd02037
634456007685	Walker A motif; other site
634456007686	FAD-dependent thymidylate synthase; Reviewed; Region: thyX; PRK00847
634456007687	Stringent starvation protein B; Region: SspB; cl01120
634456007688	fumarate hydratase; Provisional; Region: PRK15389
634456007689	Fumarate hydratase (Fumerase); Region: Fumerase; pfam05681
634456007690	Fumarase C-terminus; Region: Fumerase_C; pfam05683
634456007691	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_2; cd07253
634456007692	dimer interface [polypeptide binding]; other site
634456007693	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
634456007694	metal binding site [ion binding]; metal-binding site
634456007695	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5368
634456007696	AntA/AntB antirepressor; Region: AntA; cl01430
634456007697	Putative glucoamylase; Region: Glycoamylase; pfam10091
634456007698	D-amino acid dehydrogenase small subunit; Validated; Region: PRK00711
634456007699	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
634456007700	hydroxyglutarate oxidase; Provisional; Region: PRK11728
634456007701	Alanine racemase [Cell envelope biogenesis, outer membrane]; Region: Alr; COG0787
634456007702	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Alanine Racemase; Region: PLPDE_III_AR; cd00430
634456007703	active site
634456007704	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
634456007705	dimer interface [polypeptide binding]; other site
634456007706	substrate binding site [chemical binding]; other site
634456007707	catalytic residues [active]
634456007708	Transcriptional regulators [Transcription]; Region: Lrp; COG1522
634456007709	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
634456007710	putative DNA binding site [nucleotide binding]; other site
634456007711	putative Zn2+ binding site [ion binding]; other site
634456007712	AsnC family; Region: AsnC_trans_reg; pfam01037
634456007713	ribosome-binding factor A; Validated; Region: rbfA; PRK00521
634456007714	Bacterial translation initiation factor IF-2 associated region; Region: IF2_assoc; pfam08364
634456007715	translation initiation factor IF-2; Region: IF-2; TIGR00487
634456007716	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
634456007717	Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; Region: IF2_eIF5B; cd01887
634456007718	G1 box; other site
634456007719	putative GEF interaction site [polypeptide binding]; other site
634456007720	GTP/Mg2+ binding site [chemical binding]; other site
634456007721	Switch I region; other site
634456007722	G2 box; other site
634456007723	G3 box; other site
634456007724	Switch II region; other site
634456007725	G4 box; other site
634456007726	G5 box; other site
634456007727	This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; Region: IF2_mtIF2_II; cd03702
634456007728	Translation-initiation factor 2; Region: IF-2; pfam11987
634456007729	mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; Region: mtIF2_IVc; cd03692
634456007730	hypothetical protein; Provisional; Region: PRK09190
634456007731	Protein of unknown function (DUF448); Region: DUF448; pfam04296
634456007732	putative RNA binding cleft [nucleotide binding]; other site
634456007733	Ribosomal protein L7Ae/L30e/S12e/Gadd45 family; Region: Ribosomal_L7Ae; cl00600
634456007734	transcription elongation factor NusA; Validated; Region: nusA; PRK09202
634456007735	NusA N-terminal domain; Region: NusA_N; pfam08529
634456007736	S1_NusA: N-utilizing substance A protein (NusA), S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. NusA is a transcription elongation factor containing an N-terminal catalytic domain and three...; Region: S1_NusA; cd04455
634456007737	RNA binding site [nucleotide binding]; other site
634456007738	homodimer interface [polypeptide binding]; other site
634456007739	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
634456007740	G-X-X-G motif; other site
634456007741	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
634456007742	G-X-X-G motif; other site
634456007743	transcription termination factor NusA, C-terminal duplication; Region: nusA_Cterm_rpt; TIGR01954
634456007744	hypothetical protein; Provisional; Region: PRK14636
634456007745	Sm and related proteins; Region: Sm_like; cl00259
634456007746	Bacillus subtilis YxlS-like, C-terminal domain; Region: YlxS_C; cd01734
634456007747	putative RNA binding site [nucleotide binding]; other site
634456007748	ATP-binding subunits of Clp protease and DnaK/DnaJ chaperones [Posttranslational modification, protein turnover, chaperones]; Region: clpA; COG0542
634456007749	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
634456007750	Walker A motif; other site
634456007751	ATP binding site [chemical binding]; other site
634456007752	Walker B motif; other site
634456007753	arginine finger; other site
634456007754	Transcriptional regulator [Transcription]; Region: LysR; COG0583
634456007755	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
634456007756	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
634456007757	putative effector binding pocket; other site
634456007758	dimerization interface [polypeptide binding]; other site
634456007759	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
634456007760	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
634456007761	substrate binding pocket [chemical binding]; other site
634456007762	membrane-bound complex binding site; other site
634456007763	hinge residues; other site
634456007764	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
634456007765	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
634456007766	dimer interface [polypeptide binding]; other site
634456007767	conserved gate region; other site
634456007768	putative PBP binding loops; other site
634456007769	ABC-ATPase subunit interface; other site
634456007770	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
634456007771	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
634456007772	Walker A/P-loop; other site
634456007773	ATP binding site [chemical binding]; other site
634456007774	Q-loop/lid; other site
634456007775	ABC transporter signature motif; other site
634456007776	Walker B; other site
634456007777	D-loop; other site
634456007778	H-loop/switch region; other site
634456007779	aconitate hydratase; Validated; Region: PRK09277
634456007780	Aconitase A catalytic domain; Region: AcnA_IRP; cd01586
634456007781	substrate binding site [chemical binding]; other site
634456007782	ligand binding site [chemical binding]; other site
634456007783	Aconitase A swivel domain. This is the major form of the TCA cycle enzyme aconitate hydratase, also known as aconitase and citrate hydro-lyase. It includes bacterial and archaeal aconitase A, and the eukaryotic cytosolic form of aconitase. This group...; Region: AcnA_IRP_Swivel; cd01580
634456007784	substrate binding site [chemical binding]; other site
634456007785	cytochrome c biogenesis protein CcmA; Provisional; Region: PRK13539
634456007786	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
634456007787	Walker A/P-loop; other site
634456007788	ATP binding site [chemical binding]; other site
634456007789	Q-loop/lid; other site
634456007790	ABC transporter signature motif; other site
634456007791	Walker B; other site
634456007792	D-loop; other site
634456007793	H-loop/switch region; other site
634456007794	CcmB protein; Region: CcmB; pfam03379
634456007795	hypothetical protein; Provisional; Region: PRK10316
634456007796	YfdX protein; Region: YfdX; pfam10938
634456007797	Diaminopimelate decarboxylase [Amino acid transport and metabolism]; Region: LysA; COG0019
634456007798	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Ornithine Decarboxylase; Region: PLPDE_III_ODC; cd00622
634456007799	dimer interface [polypeptide binding]; other site
634456007800	active site
634456007801	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
634456007802	catalytic residues [active]
634456007803	substrate binding site [chemical binding]; other site
634456007804	Virulence factor BrkB; Region: Virul_fac_BrkB; pfam03631
634456007805	Lipoproteins [Cell envelope biogenesis, outer membrane]; Region: RlpA; COG0797
634456007806	Rare lipoprotein A (RlpA)-like double-psi beta-barrel; Region: DPBB_1; pfam03330
634456007807	Dehydroquinase (DHQase), type II. Dehydroquinase (or 3-dehydroquinate dehydratase) catalyzes the reversible dehydration of 3-dehydroquinate to form 3-dehydroshikimate. This reaction is part of two metabolic pathways: the biosynthetic shikimate pathway...; Region: DHQase_II; cd00466
634456007808	Dehydroquinase class II; Region: DHquinase_II; pfam01220
634456007809	trimer interface [polypeptide binding]; other site
634456007810	active site
634456007811	dimer interface [polypeptide binding]; other site
634456007812	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
634456007813	carboxyltransferase (CT) interaction site; other site
634456007814	biotinylation site [posttranslational modification]; other site
634456007815	acetyl-CoA carboxylase biotin carboxylase subunit; Validated; Region: PRK08591
634456007816	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
634456007817	ATP-grasp domain; Region: ATP-grasp_4; cl17255
634456007818	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
634456007819	MFS transporter, sugar porter (SP) family; Region: SP; TIGR00879
634456007820	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
634456007821	putative substrate translocation pore; other site
634456007822	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
634456007823	thiamine biosynthesis protein ThiC; Provisional; Region: PRK09284
634456007824	ThiC-associated domain; Region: ThiC-associated; pfam13667
634456007825	ThiC family; Region: ThiC; pfam01964
634456007826	Cupredoxin-like domain; Region: Cupredoxin_1; pfam13473
634456007827	Iron permease FTR1 family; Region: FTR1; cl00475
634456007828	Fe2+ transport protein; Region: Iron_transport; cl01377
634456007829	Carbohydrate-selective porin, OprB family; Region: OprB; pfam04966
634456007830	Probable cobalt transporter subunit (CbtA); Region: CbtA; cl02266
634456007831	Probable cobalt transporter subunit (CbtB); Region: CbtB; cl09723
634456007832	Carbohydrate-selective porin, OprB family; Region: OprB; pfam04966
634456007833	DNA-binding transcriptional activator GcvA; Provisional; Region: PRK11139
634456007834	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
634456007835	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
634456007836	dimerization interface [polypeptide binding]; other site
634456007837	4-aminobutyrate aminotransferase; Provisional; Region: PRK07495
634456007838	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
634456007839	inhibitor-cofactor binding pocket; inhibition site
634456007840	pyridoxal 5'-phosphate binding site [chemical binding]; other site
634456007841	catalytic residue [active]
634456007842	Synuclein; Region: Synuclein; pfam01387
634456007843	Uncharacterized protein family (UPF0081); Region: UPF0081; pfam03652
634456007844	aspartyl/glutamyl-tRNA amidotransferase subunit C; Reviewed; Region: gatC; PRK00034
634456007845	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases [Translation, ribosomal structure and biogenesis]; Region: GatA; COG0154
634456007846	aspartyl/glutamyl-tRNA amidotransferase subunit A; Reviewed; Region: gatA; PRK00012
634456007847	aspartyl/glutamyl-tRNA amidotransferase subunit B; Validated; Region: gatB; PRK05477
634456007848	GatB/GatE catalytic domain; Region: GatB_N; pfam02934
634456007849	GatB domain; Region: GatB_Yqey; smart00845
634456007850	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
634456007851	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
634456007852	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
634456007853	Walker A/P-loop; other site
634456007854	ATP binding site [chemical binding]; other site
634456007855	Q-loop/lid; other site
634456007856	ABC transporter signature motif; other site
634456007857	Walker B; other site
634456007858	D-loop; other site
634456007859	H-loop/switch region; other site
634456007860	Predicted EndoIII-related endonuclease [DNA replication, recombination, and repair]; Region: Nth; COG0177
634456007861	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
634456007862	minor groove reading motif; other site
634456007863	helix-hairpin-helix signature motif; other site
634456007864	substrate binding pocket [chemical binding]; other site
634456007865	active site
634456007866	ferrochelatase; Reviewed; Region: hemH; PRK00035
634456007867	Ferrochelatase, N-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_N; cd03411
634456007868	C-terminal domain interface [polypeptide binding]; other site
634456007869	active site
634456007870	Ferrochelatase, C-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_C; cd00419
634456007871	active site
634456007872	N-terminal domain interface [polypeptide binding]; other site
634456007873	A/G-specific DNA glycosylase [DNA replication, recombination, and repair]; Region: MutY; COG1194
634456007874	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
634456007875	minor groove reading motif; other site
634456007876	helix-hairpin-helix signature motif; other site
634456007877	substrate binding pocket [chemical binding]; other site
634456007878	active site
634456007879	Iron-sulfur binding domain of endonuclease III; Region: EndIII_4Fe-2S; cl15304
634456007880	DNA glycosylase (MutY in bacteria and hMYH in humans) is responsible for repairing misread  A*oxoG residues to C*G by removing the inappropriately paired adenine base from the DNA backbone. It belongs to the Nudix hydrolase superfamily and is important...; Region: DNA_Glycosylase_C; cd03431
634456007881	DNA binding and oxoG recognition site [nucleotide binding]
634456007882	Protein of unknown function (DUF721); Region: DUF721; cl02324
634456007883	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
634456007884	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
634456007885	N-acetyl-D-glucosamine binding site [chemical binding]; other site
634456007886	catalytic residue [active]
634456007887	Sporulation related domain; Region: SPOR; cl10051
634456007888	Domain of unknown function (DUF3576); Region: DUF3576; pfam12100
634456007889	leucyl-tRNA synthetase; Validated; Region: leuS; PRK00390
634456007890	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
634456007891	HIGH motif; other site
634456007892	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
634456007893	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
634456007894	active site
634456007895	KMSKS motif; other site
634456007896	Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; Region: Anticodon_Ia_Leu_BEm; cd07958
634456007897	tRNA binding surface [nucleotide binding]; other site
634456007898	Lipopolysaccharide-assembly; Region: LptE; pfam04390
634456007899	DNA polymerase III subunit delta; Reviewed; Region: holA; PRK06585
634456007900	DNA polymerase III, delta subunit; Region: DNA_pol3_delta; pfam06144
634456007901	efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family; Region: outer_NodT; TIGR01845
634456007902	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
634456007903	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
634456007904	AefR-like transcriptional repressor, C-terminal region; Region: TetR_C_7; pfam14246
634456007905	Electron transfer flavoprotein, alpha subunit [Energy production and conversion]; Region: FixB; COG2025
634456007906	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_alpha; cd01715
634456007907	Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766
634456007908	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_beta; cd01714
634456007909	Ligand binding site [chemical binding]; other site
634456007910	Electron transfer flavoprotein domain; Region: ETF; pfam01012
634456007911	Dehydrogenases (flavoproteins) [Energy production and conversion]; Region: FixC; COG0644
634456007912	hydroxyglutarate oxidase; Provisional; Region: PRK11728
634456007913	Electron transfer flavoprotein-ubiquinone oxidoreductase; Region: ETF_QO; pfam05187
634456007914	2OG-Fe(II) oxygenase superfamily; Region: 2OG-FeII_Oxy_3; pfam13640
634456007915	coproporphyrinogen III oxidase; Provisional; Region: PRK09249
634456007916	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
634456007917	FeS/SAM binding site; other site
634456007918	HemN C-terminal domain; Region: HemN_C; pfam06969
634456007919	Outer membrane protein W [Cell envelope biogenesis, outer membrane]; Region: OmpW; COG3047
634456007920	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
634456007921	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
634456007922	ligand binding site [chemical binding]; other site
634456007923	flexible hinge region; other site
634456007924	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
634456007925	putative switch regulator; other site
634456007926	non-specific DNA interactions [nucleotide binding]; other site
634456007927	DNA binding site [nucleotide binding]
634456007928	sequence specific DNA binding site [nucleotide binding]; other site
634456007929	putative cAMP binding site [chemical binding]; other site
634456007930	periplasmic serine protease, Do/DeqQ family; Region: degP_htrA_DO; TIGR02037
634456007931	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
634456007932	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
634456007933	protein binding site [polypeptide binding]; other site
634456007934	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
634456007935	protein binding site [polypeptide binding]; other site
634456007936	Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285
634456007937	nucleoside/Zn binding site; other site
634456007938	dimer interface [polypeptide binding]; other site
634456007939	catalytic motif [active]
634456007940	Predicted glutamine amidotransferases [General function prediction only]; Region: COG2071
634456007941	Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain; Region: GATase1_2; cd01745
634456007942	catalytic triad [active]
634456007943	16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187
634456007944	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
634456007945	RNA binding surface [nucleotide binding]; other site
634456007946	Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi); Region: PseudoU_synth; cl00130
634456007947	active site
634456007948	N6-adenine-specific methylase [DNA replication, recombination, and repair]; Region: COG0742
634456007949	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
634456007950	S-adenosylmethionine binding site [chemical binding]; other site
634456007951	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
634456007952	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
634456007953	dimer interface [polypeptide binding]; other site
634456007954	ssDNA binding site [nucleotide binding]; other site
634456007955	tetramer (dimer of dimers) interface [polypeptide binding]; other site
634456007956	Lipid A core - O-antigen ligase and related enzymes [Cell envelope biogenesis, outer membrane]; Region: RfaL; COG3307
634456007957	O-Antigen ligase; Region: Wzy_C; pfam04932
634456007958	RNA polymerase-binding protein DksA; Region: dksA; TIGR02420
634456007959	DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182
634456007960	active site
634456007961	catalytic residues [active]
634456007962	DNA binding site [nucleotide binding]
634456007963	Int/Topo IB signature motif; other site
634456007964	multiple promoter invertase; Provisional; Region: mpi; PRK13413
634456007965	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
634456007966	catalytic residues [active]
634456007967	catalytic nucleophile [active]
634456007968	Presynaptic Site I dimer interface [polypeptide binding]; other site
634456007969	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
634456007970	Synaptic Flat tetramer interface [polypeptide binding]; other site
634456007971	Synaptic Site I dimer interface [polypeptide binding]; other site
634456007972	DNA binding site [nucleotide binding]
634456007973	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
634456007974	DNA-binding interface [nucleotide binding]; DNA binding site
634456007975	Transposase DDE domain group 1; Region: DDE_Tnp_1_4; pfam13701
634456007976	DEAD-like helicases superfamily; Region: DEXDc; smart00487
634456007977	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
634456007978	ATP binding site [chemical binding]; other site
634456007979	putative Mg++ binding site [ion binding]; other site
634456007980	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
634456007981	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
634456007982	Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; pfam13340
634456007983	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
634456007984	This family is most closely related to the GT1 family of glycosyltransferases. WabH in Klebsiella pneumoniae has been shown to transfer a GlcNAc residue from UDP-GlcNAc onto the acceptor GalUA residue in the cellular outer core; Region: GT1_WabH_like; cd03811
634456007985	putative ADP-binding pocket [chemical binding]; other site
634456007986	tyrosyl-tRNA synthetase; Validated; Region: PRK05912
634456007987	catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805
634456007988	active site
634456007989	HIGH motif; other site
634456007990	dimer interface [polypeptide binding]; other site
634456007991	KMSKS motif; other site
634456007992	protease TldD; Provisional; Region: tldD; PRK10735
634456007993	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
634456007994	catalytic core [active]
634456007995	dTDP-D-glucose 4,6-dehydratase [Cell envelope biogenesis, outer membrane]; Region: RfbB; COG1088
634456007996	dTDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: dTDP_GD_SDR_e; cd05246
634456007997	NAD binding site [chemical binding]; other site
634456007998	substrate binding site [chemical binding]; other site
634456007999	homodimer interface [polypeptide binding]; other site
634456008000	active site
634456008001	G1P_TT_short is the short form of glucose-1-phosphate thymidylyltransferase; Region: G1P_TT_short; cd02538
634456008002	glucose-1-phosphate thymidylyltransferase, short form; Region: rmlA; TIGR01207
634456008003	substrate binding site; other site
634456008004	tetramer interface; other site
634456008005	dTDP-4-dehydrorhamnose 3,5-epimerase; Region: dTDP_sugar_isom; pfam00908
634456008006	RmlD substrate binding domain; Region: RmlD_sub_bind; pfam04321
634456008007	dTDP-6-deoxy-L-lyxo-4-hexulose reductase and related proteins, extended (e) SDRs; Region: dTDP_HR_like_SDR_e; cd05254
634456008008	NADP binding site [chemical binding]; other site
634456008009	active site
634456008010	putative substrate binding site [chemical binding]; other site
634456008011	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
634456008012	Subfamily of Glycosyltransferase Family GT2 of unknown function; Region: GT_2_like_d; cd04196
634456008013	Probable Catalytic site; other site
634456008014	Domain of unknown function (DUF4117); Region: DUF4117; pfam13491
634456008015	DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell division and chromosome partitioning]; Region: FtsK; COG1674
634456008016	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
634456008017	This domain directs oriented DNA translocation and forms a winged helix structure; Region: Ftsk_gamma; smart00843
634456008018	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
634456008019	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
634456008020	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
634456008021	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
634456008022	GST_N family, unknown subfamily 1; composed of uncharacterized proteins, predominantly from bacteria, with similarity to GSTs. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with...; Region: GST_N_1; cd03043
634456008023	Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625
634456008024	putative C-terminal domain interface [polypeptide binding]; other site
634456008025	putative GSH binding site (G-site) [chemical binding]; other site
634456008026	putative dimer interface [polypeptide binding]; other site
634456008027	C-terminal, alpha helical domain of an unknown subfamily 3 of Glutathione S-transferases; Region: GST_C_3; cd03194
634456008028	putative N-terminal domain interface [polypeptide binding]; other site
634456008029	putative dimer interface [polypeptide binding]; other site
634456008030	putative substrate binding pocket (H-site) [chemical binding]; other site
634456008031	Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain [Translation, ribosomal structure and biogenesis]; Region: TrmU; COG0482
634456008032	tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998
634456008033	Ligand Binding Site [chemical binding]; other site
634456008034	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
634456008035	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
634456008036	catalytic loop [active]
634456008037	iron binding site [ion binding]; other site
634456008038	Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism]; Region: NifS; COG1104
634456008039	cysteine desulfurase DndA; Region: DNA_S_dndA; TIGR03235
634456008040	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
634456008041	catalytic residue [active]
634456008042	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
634456008043	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
634456008044	catalytic residue [active]
634456008045	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
634456008046	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2945
634456008047	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
634456008048	rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: LasT; COG0565
634456008049	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
634456008050	cysteinyl-tRNA synthetase; Validated; Region: cysS; PRK00260
634456008051	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
634456008052	active site
634456008053	HIGH motif; other site
634456008054	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
634456008055	KMSKS motif; other site
634456008056	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
634456008057	tRNA binding surface [nucleotide binding]; other site
634456008058	anticodon binding site; other site
634456008059	Folylpolyglutamate synthase [Coenzyme metabolism]; Region: FolC; COG0285
634456008060	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
634456008061	acetyl-CoA carboxylase subunit beta; Validated; Region: PRK05654
634456008062	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682
634456008063	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
634456008064	catalytic residues [active]
634456008065	double-strand break repair helicase AddA, alphaproteobacterial type; Region: addA_alphas; TIGR02784
634456008066	Family description; Region: UvrD_C_2; pfam13538
634456008067	PD-(D/E)XK nuclease superfamily; Region: PDDEXK_1; pfam12705
634456008068	double-strand break repair protein AddB, alphaproteobacterial type; Region: addB_alphas; TIGR02786
634456008069	CRISPR/Cas system-associated protein Cas4; Region: Cas4_I-A_I-B_I-C_I-D_II-B; cl00641
634456008070	Predicted ATPase or kinase [General function prediction only]; Region: COG0802
634456008071	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
634456008072	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
634456008073	active site
634456008074	phosphorylation site [posttranslational modification]
634456008075	intermolecular recognition site; other site
634456008076	dimerization interface [polypeptide binding]; other site
634456008077	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
634456008078	DNA binding site [nucleotide binding]
634456008079	phosphoglucosamine mutase; Provisional; Region: glmM; PRK14315
634456008080	GlmM is a bacterial phosphoglucosamine mutase (PNGM) that belongs to the alpha-D-phosphohexomutase superfamily. It is required for the interconversion of glucosamine-6-phosphate and glucosamine-1-phosphate in the biosynthetic pathway of...; Region: GlmM; cd05802
634456008081	active site
634456008082	substrate binding site [chemical binding]; other site
634456008083	metal binding site [ion binding]; metal-binding site
634456008084	DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and...; Region: DHPS; cd00739
634456008085	dihydropteroate synthase; Region: DHPS; TIGR01496
634456008086	substrate binding pocket [chemical binding]; other site
634456008087	dimer interface [polypeptide binding]; other site
634456008088	inhibitor binding site; inhibition site
634456008089	FtsH Extracellular; Region: FtsH_ext; pfam06480
634456008090	ATP-dependent metalloprotease FtsH; Region: FtsH_fam; TIGR01241
634456008091	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
634456008092	Walker A motif; other site
634456008093	ATP binding site [chemical binding]; other site
634456008094	Walker B motif; other site
634456008095	arginine finger; other site
634456008096	Peptidase family M41; Region: Peptidase_M41; pfam01434
634456008097	N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases...; Region: PP-ATPase; cd01992
634456008098	tRNA(Ile)-lysidine synthase MesJ [Cell cycle control, cell division, chromosome partitioning]; Region: MesJ; COG0037
634456008099	Ligand Binding Site [chemical binding]; other site
634456008100	tol-pal system protein YbgF; Region: tol_pal_ybgF; TIGR02795
634456008101	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
634456008102	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
634456008103	ligand binding site [chemical binding]; other site
634456008104	translocation protein TolB; Provisional; Region: tolB; PRK05137
634456008105	TolB amino-terminal domain; Region: TolB_N; pfam04052
634456008106	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
634456008107	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
634456008108	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
634456008109	TolR protein; Region: tolR; TIGR02801
634456008110	TolQ protein; Region: tolQ; TIGR02796
634456008111	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
634456008112	active site
634456008113	Holliday junction DNA helicase RuvB; Reviewed; Region: ruvB; PRK00080
634456008114	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
634456008115	Walker A motif; other site
634456008116	ATP binding site [chemical binding]; other site
634456008117	Walker B motif; other site
634456008118	arginine finger; other site
634456008119	Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491
634456008120	Holliday junction DNA helicase RuvA; Reviewed; Region: ruvA; PRK00116
634456008121	RuvA N terminal domain; Region: RuvA_N; pfam01330
634456008122	RuvA, C-terminal domain; Region: RuvA_C; pfam07499
634456008123	Holliday junction resolvases (HJRs) are endonucleases that specifically resolve Holliday junction DNA intermediates during homologous recombination. HJR's occur in archaea, bacteria, and in the mitochondria of certain fungi, however this CD...; Region: RuvC_resolvase; cd00529
634456008124	active site
634456008125	putative DNA-binding cleft [nucleotide binding]; other site
634456008126	dimer interface [polypeptide binding]; other site
634456008127	hypothetical protein; Validated; Region: PRK00110
634456008128	preprotein translocase subunit SecA; Reviewed; Region: PRK12904
634456008129	SecA preprotein cross-linking domain; Region: SecA_PP_bind; smart00958
634456008130	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cl17351
634456008131	nucleotide binding region [chemical binding]; other site
634456008132	ATP-binding site [chemical binding]; other site
634456008133	SEC-C motif; Region: SEC-C; pfam02810
634456008134	peptidylprolyl isomerase; Provisional; Region: prsA; PRK00059
634456008135	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
634456008136	Ornithine acetyltransferase (OAT) family; also referred to as ArgJ. OAT catalyzes the first and fifth steps in arginine biosynthesis, coupling acetylation of glutamate with deacetylation of N-acetylornithine, which allows recycling of the acetyl group in...; Region: OAT; cd02152
634456008137	heterotetramer interface [polypeptide binding]; other site
634456008138	active site pocket [active]
634456008139	cleavage site
634456008140	RDD family; Region: RDD; pfam06271
634456008141	putative mechanosensitive channel protein; Provisional; Region: PRK11465
634456008142	Mechanosensitive ion channel; Region: MS_channel; pfam00924
634456008143	Biofilm formation and stress response factor; Region: BsmA; pfam10014
634456008144	chaperone protein DnaJ; Provisional; Region: PRK14299
634456008145	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
634456008146	HSP70 interaction site [polypeptide binding]; other site
634456008147	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
634456008148	substrate binding site [polypeptide binding]; other site
634456008149	dimer interface [polypeptide binding]; other site
634456008150	Membrane fusogenic activity; Region: BMFP; pfam04380
634456008151	Putative bacterial sensory transduction regulator; Region: YbjN; cl15834
634456008152	pyrroline-5-carboxylate reductase; Reviewed; Region: PRK11880
634456008153	NADP oxidoreductase coenzyme F420-dependent; Region: F420_oxidored; cl17232
634456008154	H+ Antiporter protein; Region: 2A0121; TIGR00900
634456008155	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
634456008156	IHF dimer interface [polypeptide binding]; other site
634456008157	IHF - DNA interface [nucleotide binding]; other site
634456008158	Rhamnan synthesis protein F; Region: RgpF; pfam05045
634456008159	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
634456008160	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
634456008161	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
634456008162	This family is most closely related to the GT1 family of glycosyltransferases. ExpE7 in Sinorhizobium meliloti has been shown to be involved in the biosynthesis of galactoglucans (exopolysaccharide II); Region: GT1_ExpE7_like; cd03823
634456008163	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
634456008164	Glycosyl transferases group 1; Region: Glyco_trans_1_4; pfam13692
634456008165	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
634456008166	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
634456008167	active site
634456008168	NAD synthetase; Reviewed; Region: nadE; PRK02628
634456008169	Glutamine aminotransferase (GAT, glutaminase) domain of glutamine-dependent NAD synthetases (class 7 and 8 nitrilases); Region: GAT_Gln-NAD-synth; cd07570
634456008170	multimer interface [polypeptide binding]; other site
634456008171	active site
634456008172	catalytic triad [active]
634456008173	protein interface 1 [polypeptide binding]; other site
634456008174	NAD+ synthase is a homodimer, which catalyzes the final step in de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis, an amide transfer from either ammonia or glutamine to nicotinic acid adenine dinucleotide (NaAD). The conversion of NaAD to NAD...; Region: NAD_synthase; cd00553
634456008175	homodimer interface [polypeptide binding]; other site
634456008176	NAD binding pocket [chemical binding]; other site
634456008177	ATP binding pocket [chemical binding]; other site
634456008178	Mg binding site [ion binding]; other site
634456008179	active-site loop [active]
634456008180	Imidazoleglycerol-phosphate dehydratase; Region: IGPD; cd07914
634456008181	putative active site pocket [active]
634456008182	4-fold oligomerization interface [polypeptide binding]; other site
634456008183	metal binding residues [ion binding]; metal-binding site
634456008184	3-fold/trimer interface [polypeptide binding]; other site
634456008185	imidazole glycerol phosphate synthase subunit HisH; Provisional; Region: hisH; PRK13146
634456008186	Type 1 glutamine amidotransferase (GATase1) domain found in imidazole glycerol phosphate synthase (IGPS); Region: GATase1_IGP_Synthase; cd01748
634456008187	putative active site [active]
634456008188	oxyanion strand; other site
634456008189	catalytic triad [active]
634456008190	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
634456008191	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
634456008192	Coenzyme A binding pocket [chemical binding]; other site
634456008193	HisA.  Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase catalyzes the fourth step in histidine biosynthesis, an isomerisation of the aminoaldose moiety of ProFAR to the aminoketose of PRFAR (N-(5'-phospho-D-1...; Region: HisA; cd04732
634456008194	phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; Region: TIGR00007
634456008195	catalytic residues [active]
634456008196	The cyclase subunit of imidazoleglycerol phosphate synthase (HisF). Imidazole glycerol phosphate synthase (IGPS) catalyzes the fifth step of histidine biosynthesis, the formation of the imidazole ring. IGPS converts N1-(5'-phosphoribulosyl)...; Region: HisF; cd04731
634456008197	Histidine biosynthesis protein; Region: His_biosynth; pfam00977
634456008198	substrate binding site [chemical binding]; other site
634456008199	glutamase interaction surface [polypeptide binding]; other site
634456008200	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in Escherichia coli phosphoribosyl-ATP pyrophosphohydrolase (HisIE or PRATP-PH) and its homologs; Region: NTP-PPase_HisIE_like; cd11534
634456008201	metal binding site [ion binding]; metal-binding site
634456008202	Protein Kinase C Interacting protein related (PKCI): PKCI and related proteins belong to the ubiquitous HIT family of hydrolases that act on alpha-phosphates of ribonucleotides. The members of this subgroup have a conserved HxHxHxx motif (x is a...; Region: PKCI_related; cd01276
634456008203	nucleotide binding site/active site [active]
634456008204	HIT family signature motif; other site
634456008205	catalytic residue [active]
634456008206	Nitroreductase-like family which includes NADH oxidase and arsenite oxidiase. NADH oxidase catalyses the oxidation of NAD(P)H and accepts a wide broad range of compounds as electron acceptors, such as nitrocompound. Arsenite oxidase in a...; Region: Arsenite_oxidase; cd02135
634456008207	putative FMN binding site [chemical binding]; other site
634456008208	hypothetical protein; Provisional; Region: PRK09126
634456008209	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
634456008210	Domain of unknown function (DUF4186); Region: DUF4186; pfam13811
634456008211	Phosphate-starvation-inducible E; Region: PsiE; pfam06146
634456008212	Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625
634456008213	GST_N family, Saccharomyces cerevisiae GTT1-like subfamily; composed of predominantly uncharacterized proteins with similarity to the S. cerevisiae GST protein, GTT1, and the Schizosaccharomyces pombe GST-III. GSTs are cytosolic dimeric proteins involved...; Region: GST_N_GTT1_like; cd03046
634456008214	putative C-terminal domain interface [polypeptide binding]; other site
634456008215	putative GSH binding site (G-site) [chemical binding]; other site
634456008216	putative dimer interface [polypeptide binding]; other site
634456008217	C-terminal, alpha helical domain of GTT1-like Glutathione S-transferases; Region: GST_C_GTT1_like; cd03189
634456008218	putative N-terminal domain interface [polypeptide binding]; other site
634456008219	putative dimer interface [polypeptide binding]; other site
634456008220	putative substrate binding pocket (H-site) [chemical binding]; other site
634456008221	ParB/RepB/Spo0J family partition protein; Region: parB_part; TIGR00180
634456008222	ParB-like nuclease domain; Region: ParB; smart00470
634456008223	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
634456008224	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
634456008225	P-loop; other site
634456008226	Magnesium ion binding site [ion binding]; other site
634456008227	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
634456008228	Magnesium ion binding site [ion binding]; other site
634456008229	Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division [Cell envelope biogenesis, outer membrane]; Region: GidB; COG0357
634456008230	16S rRNA methyltransferase GidB; Reviewed; Region: gidB; PRK00107
634456008231	tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; Validated; Region: PRK05192
634456008232	tRNA (uracil-5-)-methyltransferase Gid; Reviewed; Region: PRK05335
634456008233	GidA associated domain 3; Region: GIDA_assoc_3; pfam13932
634456008234	tRNA modification GTPase TrmE; Reviewed; Region: trmE; PRK05291
634456008235	GTP-binding protein TrmE N-terminus; Region: TrmE_N; pfam10396
634456008236	trmE is a tRNA modification GTPase; Region: trmE; cd04164
634456008237	G1 box; other site
634456008238	GTP/Mg2+ binding site [chemical binding]; other site
634456008239	Switch I region; other site
634456008240	G2 box; other site
634456008241	Switch II region; other site
634456008242	G3 box; other site
634456008243	G4 box; other site
634456008244	G5 box; other site
634456008245	Catalytic cysteine-containing C-terminus of GTPase, MnmE; Region: GTPase_Cys_C; pfam12631
634456008246	Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]; Region: Ada; COG0350
634456008247	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
634456008248	DNA binding site [nucleotide binding]
634456008249	active site
634456008250	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
634456008251	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
634456008252	Possible lysine decarboxylase; Region: Lysine_decarbox; cl00695
634456008253	major facilitator superfamily transporter; Provisional; Region: PRK05122
634456008254	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
634456008255	putative substrate translocation pore; other site
634456008256	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
634456008257	dimer interface [polypeptide binding]; other site
634456008258	ADP-ribose binding site [chemical binding]; other site
634456008259	active site
634456008260	nudix motif; other site
634456008261	metal binding site [ion binding]; metal-binding site
634456008262	Uncharacterized protein family (UPF0093); Region: UPF0093; pfam03653
634456008263	Predicted phosphatases [General function prediction only]; Region: Gph; COG0546
634456008264	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
634456008265	motif II; other site
634456008266	Uroporphyrinogen decarboxylase (URO-D) is a dimeric cytosolic enzyme that decarboxylates the four acetate side chains of uroporphyrinogen III (uro-III) to create coproporphyrinogen III, without requiring any prosthetic groups or cofactors. This reaction...; Region: URO-D; cd00717
634456008267	substrate binding site [chemical binding]; other site
634456008268	active site
634456008269	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
634456008270	active site
634456008271	dimer interface [polypeptide binding]; other site
634456008272	Uncharacterized protein conserved in bacteria (DUF2213); Region: DUF2213; pfam09979
634456008273	Phage Terminase; Region: Terminase_1; pfam03354
634456008274	multiple promoter invertase; Provisional; Region: mpi; PRK13413
634456008275	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
634456008276	catalytic residues [active]
634456008277	catalytic nucleophile [active]
634456008278	Presynaptic Site I dimer interface [polypeptide binding]; other site
634456008279	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
634456008280	Synaptic Flat tetramer interface [polypeptide binding]; other site
634456008281	Synaptic Site I dimer interface [polypeptide binding]; other site
634456008282	DNA binding site [nucleotide binding]
634456008283	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
634456008284	DNA-binding interface [nucleotide binding]; DNA binding site
634456008285	hypothetical protein; Provisional; Region: PRK14709
634456008286	D5 N terminal like; Region: D5_N; smart00885
634456008287	Prim_Pol: Primase-polymerase (primpol) domain of the type found in bifunctional replicases from archaeal plasmids, including ORF904 protein of the crenarchaeal plasmid pRN1 from Sulfolobus islandicus (pRN1 primpol). These primpol domains belong to the...; Region: Prim_Pol; cd04859
634456008288	polymerase nucleotide-binding site; other site
634456008289	DNA-binding residues [nucleotide binding]; DNA binding site
634456008290	nucleotide binding site [chemical binding]; other site
634456008291	primase nucleotide-binding site [nucleotide binding]; other site
634456008292	Primase C terminal 1 (PriCT-1); Region: PriCT_1; cl07362
634456008293	multiple promoter invertase; Provisional; Region: mpi; PRK13413
634456008294	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
634456008295	catalytic residues [active]
634456008296	catalytic nucleophile [active]
634456008297	Presynaptic Site I dimer interface [polypeptide binding]; other site
634456008298	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
634456008299	Synaptic Flat tetramer interface [polypeptide binding]; other site
634456008300	Synaptic Site I dimer interface [polypeptide binding]; other site
634456008301	DNA binding site [nucleotide binding]
634456008302	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
634456008303	DNA-binding interface [nucleotide binding]; DNA binding site
634456008304	Predicted nucleic acid-binding protein, contains PIN domain [General function prediction only]; Region: COG1569
634456008305	Conjugal transfer protein TraD; Region: TraD; pfam06412
634456008306	putative transposase OrfB; Reviewed; Region: PHA02517
634456008307	HTH-like domain; Region: HTH_21; pfam13276
634456008308	Integrase core domain; Region: rve; pfam00665
634456008309	Integrase core domain; Region: rve_3; pfam13683
634456008310	Transposase; Region: HTH_Tnp_1; cl17663
634456008311	Hint domain; Region: Hint_2; pfam13403
634456008312	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
634456008313	Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; pfam13340
634456008314	Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or C-terminal to the catalytic domain. These enzymes perform site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining...; Region: Ser_Recombinase; cl02788
634456008315	HTH-like domain; Region: HTH_21; pfam13276
634456008316	Integrase core domain; Region: rve; pfam00665
634456008317	Integrase core domain; Region: rve_3; pfam13683
634456008318	Transposase; Region: HTH_Tnp_1; pfam01527
634456008319	Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or C-terminal to the catalytic domain. These enzymes perform site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining...; Region: Ser_Recombinase; cl02788
634456008320	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
634456008321	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
634456008322	DNA-binding interface [nucleotide binding]; DNA binding site
634456008323	multiple promoter invertase; Provisional; Region: mpi; PRK13413
634456008324	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
634456008325	catalytic residues [active]
634456008326	catalytic nucleophile [active]
634456008327	Presynaptic Site I dimer interface [polypeptide binding]; other site
634456008328	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
634456008329	Synaptic Flat tetramer interface [polypeptide binding]; other site
634456008330	Synaptic Site I dimer interface [polypeptide binding]; other site
634456008331	DNA binding site [nucleotide binding]
634456008332	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
634456008333	DNA-binding interface [nucleotide binding]; DNA binding site
634456008334	Winged helix-turn helix; Region: HTH_29; pfam13551
634456008335	Helix-turn-helix domain; Region: HTH_28; pfam13518
634456008336	Homeodomain-like domain; Region: HTH_32; pfam13565
634456008337	Integrase core domain; Region: rve; pfam00665
634456008338	Integrase core domain; Region: rve_3; cl15866
634456008339	Mu transposase, C-terminal; Region: Mu-transpos_C; pfam09299
634456008340	Uncharacterized ATPase, putative transposase [General function prediction only]; Region: COG2842
634456008341	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
634456008342	multiple promoter invertase; Provisional; Region: mpi; PRK13413
634456008343	catalytic residues [active]
634456008344	catalytic nucleophile [active]
634456008345	Presynaptic Site I dimer interface [polypeptide binding]; other site
634456008346	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
634456008347	Synaptic Flat tetramer interface [polypeptide binding]; other site
634456008348	Synaptic Site I dimer interface [polypeptide binding]; other site
634456008349	DNA binding site [nucleotide binding]
634456008350	ParA-like protein; Provisional; Region: PHA02518
634456008351	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
634456008352	P-loop; other site
634456008353	Magnesium ion binding site [ion binding]; other site
634456008354	Replication initiator protein A; Region: RPA; pfam10134
634456008355	Protein of unknown function (DUF2442); Region: DUF2442; pfam10387
634456008356	putative addiction module antidote; Region: doc_partner; TIGR02609
634456008357	Prophage maintenance system killer protein [General function prediction only]; Region: Doc; COG3654
634456008358	Antitoxin of toxin-antitoxin stability system N-terminal; Region: RelB_N; pfam12910
634456008359	PIN domain of the VapC-like Sll0205 protein and homologs; Region: PIN_Sll0205; cd09872
634456008360	putative active site [active]
634456008361	Protein of unknown function (DUF3680); Region: DUF3680; pfam12441
634456008362	Conjugal transfer protein TraD; Region: TraD; pfam06412
634456008363	conjugal transfer relaxase TraA; Provisional; Region: PRK13889
634456008364	MobA/MobL family; Region: MobA_MobL; pfam03389
634456008365	AAA domain; Region: AAA_30; pfam13604
634456008366	Family description; Region: UvrD_C_2; pfam13538
634456008367	Plasmid stability protein [General function prediction only]; Region: StbC; COG4691
634456008368	PIN domain of ribonucleases (toxins), VapC and FitB, of prokaryotic toxin/antitoxin operons, Pyrococcus horikoshii protein PH0500, and other similar bacterial and archaeal homologs; Region: PIN_VapC-FitB; cd09881
634456008369	oligomeric interface; other site
634456008370	putative active site [active]
634456008371	homodimer interface [polypeptide binding]; other site
634456008372	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cl14632
634456008373	Transposase DDE domain group 1; Region: DDE_Tnp_1_4; pfam13701
634456008374	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
634456008375	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
634456008376	catalytic residues [active]
634456008377	catalytic nucleophile [active]
634456008378	AAA domain; Region: AAA_31; pfam13614
634456008379	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
634456008380	P-loop; other site
634456008381	Magnesium ion binding site [ion binding]; other site
634456008382	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cl17200
634456008383	non-specific DNA binding site [nucleotide binding]; other site
634456008384	salt bridge; other site
634456008385	sequence-specific DNA binding site [nucleotide binding]; other site
634456008386	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
634456008387	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: Tra5; COG2801
634456008388	HTH-like domain; Region: HTH_21; pfam13276
634456008389	Integrase core domain; Region: rve; pfam00665
634456008390	Integrase core domain; Region: rve_3; pfam13683
634456008391	Transposase; Region: HTH_Tnp_1; pfam01527
634456008392	T5orf172 domain; Region: T5orf172; pfam10544
634456008393	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
634456008394	DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair]; Region: SSL2; COG1061
634456008395	Pseudomurein-binding repeat; Region: PMBR; pfam09373
634456008396	Type II restriction enzyme, methylase subunits [Defense mechanisms]; Region: COG1002
634456008397	Methyltransferase domain; Region: Methyltransf_26; pfam13659
634456008398	Fic family protein [Function unknown]; Region: COG3177
634456008399	Fic/DOC family N-terminal; Region: Fic_N; pfam13784
634456008400	Fic/DOC family; Region: Fic; pfam02661
634456008401	PemK-like protein; Region: PemK; pfam02452
634456008402	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
634456008403	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
634456008404	Presynaptic Site I dimer interface [polypeptide binding]; other site
634456008405	catalytic residues [active]
634456008406	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
634456008407	Synaptic Flat tetramer interface [polypeptide binding]; other site
634456008408	Synaptic Site I dimer interface [polypeptide binding]; other site
634456008409	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
634456008410	DNA-binding interface [nucleotide binding]; DNA binding site
634456008411	Transposase DDE domain group 1; Region: DDE_Tnp_1_4; pfam13701
634456008412	Hint domain; Region: Hint_2; pfam13403
634456008413	Transposase; Region: HTH_Tnp_1; pfam01527
634456008414	HTH-like domain; Region: HTH_21; pfam13276
634456008415	Integrase core domain; Region: rve; pfam00665
634456008416	Integrase core domain; Region: rve_3; pfam13683
634456008417	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cl17200
634456008418	non-specific DNA binding site [nucleotide binding]; other site
634456008419	salt bridge; other site
634456008420	sequence-specific DNA binding site [nucleotide binding]; other site
634456008421	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
634456008422	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
634456008423	P-loop; other site
634456008424	Magnesium ion binding site [ion binding]; other site
634456008425	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cl17220