-- dump date 20140620_073927 -- class Genbank::CDS -- table cds_note -- id note YP_005743406.1 Required for DNA replication; binds preferentially to single-stranded, linear DNA YP_005743407.1 TIGRFAM: DNA gyrase, B subunit PFAM: DNA gyrase, subunit B domain protein; ATP-binding region, ATPase domain protein domain protein; TOPRIM domain protein; DNA topoisomerase, type IIA, subunit B, region 2 domain protein SMART: DNA topoisomerase II YP_005743410.1 catalyzes the degradation of histidine to urocanate and ammmonia YP_005743416.1 Contains a modified GGDEF domain and a DHH domainPossibly involved in signal transduction mechanisms YP_005743420.1 also known as vicR and yycF YP_005743421.1 Also known as VicK and YycG YP_005743423.1 Possible negative regulator of walKR two-component response regulator YP_005743426.1 Orthologs present in other SA genomes with alternative initiation codon. YP_005743437.1 PFAM: glycerophosphoryl diester phosphodiesterase KEGG: sha:SH0089 hypothetical protein YP_005743442.1 Contains a XylR carbohydrate kinase domain YP_005743451.1 possible remnant of radC-like protein YP_005743452.1 ortholog of Staphylococcus epidermidis hypothetical protein YP_005743477.1 PFAM: helix-turn-helix- domain containing protein AraC type KEGG: sav:SAV0101 hypothetical protein YP_005743483.1 TIGRFAM: L-lactate transport PFAM: L-lactate permease KEGG: sab:SAB0049 L-lactate permease YP_005743485.1 TIGRFAM: staphylococcal accessory regulator family PFAM: regulatory protein, MarR YP_005743489.1 identified by match to protein family HMM PF00291 YP_005743494.1 PFAM: IucA/IucC family protein KEGG: sav:SAV0121 similar to siderophore biosynthesis protein YP_005743500.1 PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase; Male sterility domain KEGG: sab:SAB0067 probable UDP-glucose 4-epimerase YP_005743502.1 PFAM: glycosyl transferase group 1 KEGG: sav:SAV0130 hypothetical protein YP_005743503.1 PFAM: O-antigen ligase KEGG: sav:SAV0131 hypothetical protein YP_005743512.1 TIGRFAM: phosphonate ABC transporter, inner membrane subunit PFAM: binding-protein-dependent transport systems inner membrane component KEGG: sao:SAOUHSC_00102 phosphonates ABC transporter, permease protein CC0363, putative YP_005743513.1 TIGRFAM: phosphonate ABC transporter, inner membrane subunit PFAM: binding-protein-dependent transport systems inner membrane component YP_005743519.1 Contains Zn binding and helix-turn-helix domains YP_005743523.1 identified by match to protein family HMM PF02811 YP_005743525.1 PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; Male sterility domain; Polysaccharide biosynthesis domain protein KEGG: sas:SAS0128 capsular polysaccharide synthesis enzyme YP_005743526.1 PFAM: NAD-dependent epimerase/dehydratase; Male sterility domain KEGG: sav:SAV0154 capsular polysaccharide synthesis enzyme Cap5F YP_005743527.1 identified by match to protein family HMM PF02350; match to protein family HMM TIGR00236 YP_005743533.1 PFAM: sugar transferase KEGG: sao:SAOUHSC_00126 capsular polysaccharide biosynthesis protein Cap8M YP_005743534.1 PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase; Male sterility C-terminal domain YP_005743535.1 PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase, dimerisation; UDP-glucose/GDP-mannose dehydrogenase-like YP_005743536.1 PFAM: UDP-N-acetylglucosamine 2-epimerase KEGG: sav:SAV0164 capsular polysaccharide synthesis enzyme Cap5P YP_005743539.1 PFAM: aldehyde dehydrogenase KEGG: sam:MW0142 aldehyde dehydrogenase homologue YP_005743546.1 similar to acyl-CoA dehydrogenase family protein YP_005743557.1 PFAM: isochorismatase hydrolase KEGG: sas:SAS0162 putative isochorismatase YP_005743562.1 similar to PTS system sucrose-specific IIBC component YP_005743563.1 identified by match to protein family HMM PF01380; match to protein family HMM PF01418 YP_005743566.1 PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein SMART: AAA ATPase KEGG: sav:SAV0205 oligopeptide transport ATP-binding protein YP_005743570.1 TIGRFAM: gamma-glutamyltransferase PFAM: gamma-glutamyltranspeptidase KEGG: sav:SAV0209 gamma-glutamyltranspeptidase YP_005743571.1 PFAM: NAD(P)H dehydrogenase (quinone) KEGG: sao:SAOUHSC_00173 acyl carrier phosphodiesterase YP_005743577.1 PFAM: oxidoreductase domain protein; Oxidoreductase domain KEGG: sau:SA0210 hypothetical protein YP_005743583.1 PFAM: histidine kinase internal region KEGG: sav:SAV0224 similar to two-component sensor histidine kinase YP_005743594.1 PFAM: AMP-dependent synthetase and ligase KEGG: sav:SAV0234 long-chain fatty-acid-CoA ligase YP_005743606.1 PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; M trans-acting positive regulator; PRD domain protein; Helix-turn-helix type 11 domain protein KEGG: sav:SAV0244 similar to transcription antiterminator (BglG family) homolog YP_005743613.1 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesi YP_005743615.1 PFAM: CDP-glycerol:poly(glycerophosphate) glycerophosphotransferase KEGG: sav:SAV0253 similar to teichoic acid biosynthesis protein B YP_005743616.1 Sequence at least partially present in other S. aureues genomes but not annotated as CDS YP_005743618.1 involved in isoprenoid and isopentenyl-PP biosynthesis YP_005743620.1 PFAM: CDP-glycerol:poly(glycerophosphate) glycerophosphotransferase KEGG: sav:SAV0253 similar to teichoic acid biosynthesis protein B YP_005743624.1 PFAM: response regulator receiver; LytTr DNA-binding region-containing protein KEGG: sao:SAOUHSC_00231 two-component response regulator, putative YP_005743625.1 negatively regulates murein hydrolase activity YP_005743635.1 PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator KEGG: sao:SAOUHSC_00242 hypothetical protein YP_005743637.1 PFAM: major facilitator superfamily MFS_1 KEGG: sav:SAV0274 similar to transmembrane efflux pump protein YP_005743638.1 member of linear amide C-N hydrolase / choloylglycine hydrolase family YP_005743639.1 also called lysostaphin YP_005743650.1 PFAM: cell division protein FtsK/SpoIIIE KEGG: sav:SAV0287 similar to DNA segregation ATPase and related proteins YP_005743660.1 part of tandem array of 10 proteins in Staphylococcus aureus YP_005743662.1 Ortholog of SERP0504 from S. epidermidis YP_005743663.1 Ortholog of SERP0505 from S. epidermidis YP_005743672.1 contains phosphotransferase system fructose-specific IIC component domain YP_005743673.1 PFAM: PfkB domain protein KEGG: sar:SAR0308 PfkB family carbohydrate kinase YP_005743675.1 PFAM: Na dependent nucleoside transporter; nucleoside recognition domain protein; Na dependent nucleoside transporter domain protein KEGG: sav:SAV0313 probable pyrimidine nucleoside transport protein YP_005743676.1 TIGRFAM: SSS sodium solute transporter superfamily PFAM: Na+? symporter KEGG: sav:SAV0314 solute:Na+ symporter, SSS family YP_005743684.1 some domain similarity with lipase, esterase, hydrolase YP_005743689.1 some similarity to NAD-dependent protein deacetylases, SIR2 family YP_005743696.1 MepR represses expression of MepA and MepB as well as autoregulating its own expression YP_005743697.1 part of mepABR system YP_005743698.1 The mepRAB gene cluster of Staphylococcus aureus encodes a MarR family repressor (MepR; known to repress mepA expression), a MATE family multidrug efflux pump (MepA), and a protein of unknown function (MepB). YP_005743705.1 PFAM: GCN5-related N-acetyltransferase KEGG: sav:SAV0342 similar to ribosomal-protein-serine N-acetyltransferase YP_005743718.1 potentially involved in antibiotic synthesis YP_005743738.1 Staphylococcus aureus pathogenicity island; identified by similarity to GB:AAG29614.1 YP_005743740.1 Ortholog hypothetical protein SH2094. Contains a primase domain. YP_005743742.1 ortholog of hypothetical protein SH2092. Putative phage-associated protein. YP_005743743.1 Ortholog of hypothetical protein SAV0793 YP_005743752.1 Homology to bovine pathogenicity island protein Orf3 YP_005743754.1 putative staphylococcal enterotoxin YP_005743765.1 PFAM: nitroreductase KEGG: sav:SAV0382 hypothetical protein, similar to nitro/flavin reductase YP_005743775.1 ortholog (SAV0395) in Staphylococcus aureus subsp. aureus Mu50 YP_005743776.1 Present in Mu50 and Mu3, hypothetical protein SAHV_0394 [Staphylococcus aureus subsp. aureus Mu3] YP_005743777.1 orthologs in Mu3 and Mu50, tetracycline resistance protein [Staphylococcus aureus subsp. aureus Mu50] YP_005743778.1 orthologs present in Mu3 and Mu50 YP_005743779.1 orthologs present Mu3 and Mu50, similar to lipoprotein, NLP/P60 family YP_005743780.1 Contains weak transmembrane amino acid transporter protein domain YP_005743797.1 Similar to USA300HOU_0415 YP_005743806.1 these proteins share structural homology to known superantigen proteins but do not exhibit any of the properties expected such as histocompatibility complex class II binding or broad T-cell activation YP_005743810.1 these proteins share structural homology to known superantigen proteins but do not exhibit any of the properties expected such as histocompatibility complex class II binding or broad T-cell activation YP_005743812.1 Pathogenicity island SaPIn2 YP_005743813.1 Pathogenicity island SaPIn2 YP_005743819.1 identified by match to protein family HMM PF04507; match to protein family HMM TIGR01742 YP_005743821.1 identified by match to protein family HMM PF04507; match to protein family HMM TIGR01742 YP_005743822.1 TIGRFAM: putative lipoprotein PFAM: protein of unknown function DUF576 YP_005743823.1 identified by match to protein family HMM PF04507; match to protein family HMM TIGR01742 YP_005743829.1 PFAM: cobalamin synthesis protein P47K; cobalamin synthesis CobW domain protein KEGG: sav:SAV0450 putative cobalamin synthesis protein YP_005743847.1 identified by match to protein family HMM PF01476; match to protein family HMM PF05257 YP_005743849.1 PFAM: NUDIX hydrolase KEGG: sab:SAB0416 hypothetical protein YP_005743852.1 PFAM: YibE/F family protein KEGG: sao:SAOUHSC_00433 hypothetical protein YP_005743857.1 TIGRFAM: trehalose operon repressor PFAM: regulatory protein GntR HTH; UbiC transcription regulator-associated domain protein KEGG: sao:SAOUHSC_00439 hypothetical protein YP_005743865.1 KEGG: sav:SAV0484 probable DNA polymerase III delta prime subunit YP_005743875.1 PFAM: protein of unknown function DUF1021 YP_005743878.1 may also be involved in the regulation of purine biosynthesis YP_005743883.1 the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress respon YP_005743887.1 PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; MazG nucleotide pyrophosphohydrolase KEGG: sav:SAV0505 nucleoside triphosphate pyrophosphohydrolase-like protein YP_005743889.1 identified by similarity to EGAD:12437; match to protein family HMM PF04977 YP_005743895.1 TIGRFAM: cysteine synthase; cysteine synthase A PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit KEGG: sao:SAOUHSC_00488 hypothetical protein YP_005743902.1 PFAM: SNO glutamine amidotransferase KEGG: sao:SAOUHSC_00500 glutamine amidotransferase YP_005743905.1 Other SA genomes have given this protein a gene name 'ssaA'.It is a putative UvrB/uvrC motif domain protein. YP_005743907.1 PFAM: UvrB/UvrC protein; AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein SMART: AAA ATPase KEGG: sao:SAOUHSC_00505 endopeptidase, putative YP_005743915.1 identified by similarity to EGAD:14028; match to protein family HMM PF05991 YP_005743917.1 forms a complex with SecY and SecG; SecYEG forms a putative protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force YP_005743922.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulat YP_005743924.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme YP_005743934.1 Catalyzes the phosphorylation of ribulose to ribulose 5-phosphate. Potential pseudogene, missing several aa from N-term, premature stop codon YP_005743946.1 PFAM: glycosyl transferase group 1; Protein of unknown function DUF1975 KEGG: sav:SAV0564 similar to poly (glycerol-phosphate) alpha-glucosyltransferase YP_005743947.1 PFAM: glycosyl transferase group 1; Protein of unknown function DUF1975 KEGG: sav:SAV0565 similar to poly (glycerol-phosphate) alpha-glucosyltransferase YP_005743952.1 involved in the final step of pyrimidine biosynthesis YP_005743956.1 PFAM: AMP-dependent synthetase and ligase. Identified by match to protein family HMM PF00501 YP_005743958.1 KEGG: sao:SAOUHSC_00559 hypothetical protein. Called vraC in Saa_SO385 YP_005743977.1 some homology to a putative Bacillus transposase YP_005743982.1 Present in USA300 YP_005743994.1 contains a HD sub domain YP_005743995.1 YwhD familly protein YP_005744009.1 protein conserved in S.aureus but unannotated YP_005744012.1 phage integrase family protein YP_005744013.1 subunit A of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali YP_005744014.1 subunit B of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali YP_005744015.1 subunit C of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali YP_005744016.1 subunit D of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; contains an oxidoreductase domain; catalyzes the transfer of electrons from NADH to ubiquinone; in S. meliloti it is known to be involved specifica YP_005744017.1 subunit E of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; in S. meliloti it is known to be involved specifically with K+ transport YP_005744018.1 subunit F of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali YP_005744019.1 subunit G of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali YP_005744024.1 identified by similarity to GP:1617434; match to protein family HMM PF01325; match to protein family HMM PF02742; match to protein family HMM PF04023 YP_005744027.1 PFAM: ABC transporter related SMART: AAA ATPase YP_005744044.1 PFAM: Alpha/beta hydrolase fold-3 domain protein KEGG: sau:SA0610 hypothetical protein YP_005744050.1 PFAM: ABC transporter related SMART: AAA ATPase YP_005744073.1 BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell YP_005744076.1 identified by match to protein family HMM PF01047 YP_005744077.1 PFAM: cobalamin synthesis protein, P47K; cobalamin synthesis CobW domain protein YP_005744078.1 PFAM: aldo/keto reductase KEGG: sav:SAV0688 similar to oxidoreductase, aldo/keto reductase family YP_005744081.1 PFAM: DNA photolyase FAD-binding KEGG: sav:SAV0691 putative deoxyribodipyrimidine photolyase YP_005744083.1 PFAM: protein of unknown function DUF296 KEGG: sao:SAOUHSC_00702 hypothetical protein YP_005744091.1 PFAM: CBS domain containing protein; protein of unknown function DUF21; transporter-associated region KEGG: sao:SAOUHSC_00711 hypothetical protein YP_005744092.1 PFAM: aldo/keto reductase KEGG: sav:SAV0703 similar to oxidoreductase, aldo/keto reductase family YP_005744097.1 contains signal peptide sequence YP_005744109.1 TIGRFAM: ATP-dependent DNA helicase, RecQ family; ATP-dependent DNA helicase RecQ PFAM: helicase domain protein; HRDC domain protein; DEAD/DEAH box helicase domain protein SMART: DEAD-like helicases-like YP_005744111.1 PFAM: binding-protein-dependent transport systems inner membrane component; Substrate-binding region of ABC-type glycine betaine transport system KEGG: sao:SAOUHSC_00732 amino acid ABC transporter, permease protein, putative YP_005744112.1 TIGRFAM: histidinol-phosphate aminotransferase PFAM: aminotransferase class I and II KEGG: sao:SAOUHSC_00733 histidinol-phosphate aminotransferase YP_005744113.1 identified by similarity to EGAD:107442; match to protein family HMM PF06941 YP_005744114.1 identified by match to protein family HMM PF00781; match to protein family HMM TIGR00147 YP_005744124.1 lipoprotein, similar to ferrichrome ABC transporter YP_005744135.1 PFAM: glycosyl transferase family 4 KEGG: sav:SAV0747 lipophilic protein affecting bacterial lysis rate and methicillin resistance level YP_005744137.1 identified by match to protein family HMM PF02645; match to protein family HMM TIGR00762 YP_005744143.1 Some domain similarity with CHAP and PRK08581 (amidase) and, lysM (lysin motif). YP_005744154.1 2-phospho-L-lactate transferase (CofD) related protein YP_005744166.1 SecG forms a complex with SecY and SecE. SecA then recruits the SecYEG complex to form an active protein translocation channel. YP_005744177.1 KEGG: sav:SAV0814 hypothetical protein YP_005744178.1 PFAM: nuclease (SNase domain protein) YP_005744179.1 identified by match to protein family HMM PF00313 YP_005744199.1 KEGG: ser:SERP2508 transposase C YP_005744201.1 PFAM: ribosomal RNA adenine methylase transferase; putative methyltransferase KEGG: ser:SERP2510 rRNA adenine N-6-methyltransferase YP_005744202.1 PFAM: Cyclopropane-fatty-acyl-phospholipid synthase; methyltransferase small; Methyltransferase type 11; Methyltransferase type 12 YP_005744206.1 identified by match to protein family HMM PF00005 YP_005744213.1 Similar to SaPI1 Orf21 YP_005744231.1 PFAM: protein of unknown function DUF368 KEGG: sav:SAV0841 similar to integral membrane protein YP_005744242.1 identified by similarity to GP:10176077; match to protein family HMM PF01925 YP_005744244.1 catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group YP_005744271.1 subunit A of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali YP_005744278.1 PFAM: glycerophosphoryl diester phosphodiesterase KEGG: sao:SAOUHSC_00897 hypothetical protein YP_005744282.1 PFAM: SNARE associated Golgi protein YP_005744283.1 TIGRFAM: signal peptidase I PFAM: peptidase S24 S26A and S26B KEGG: sas:SAS0834 putative signal peptidase Ia YP_005744284.1 TIGRFAM: signal peptidase I PFAM: peptidase S24 S26A and S26B KEGG: sas:SAS0835 signal peptidase Ib YP_005744292.1 PFAM: acyltransferase 3 KEGG: sas:SAS0844 hypothetical protein YP_005744293.1 PFAM: AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein SMART: AAA ATPase KEGG: sav:SAV0975 ClpB chaperone homologue YP_005744300.1 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters YP_005744309.1 TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein SMART: AAA ATPase KEGG: sav:SAV0992 oligopeptide ABC transporter ATP-binding protein homologue YP_005744310.1 TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein SMART: AAA ATPase KEGG: sav:SAV0993 oligopeptide transport system ATP-binding protein AppF homologue YP_005744312.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_005744316.1 TIGRFAM: oligoendopeptidase F PFAM: peptidase M3A and M3B thimet/oligopeptidase F; Oligopeptidase F KEGG: sas:SAS0870 putative oligopeptidase YP_005744322.1 catalyzes the phosphorylation of NAD to NADP YP_005744327.1 Catalyzes a key regulatory step in fatty acid biosynthesis YP_005744328.1 member of the PurR regulon YP_005744331.1 Some domain similarity with 2'-5' RNA ligase (Translation, ribosomal structure and biogenesis) YP_005744338.1 PFAM: peptidase S1 and S6 chymotrypsin/Hap SMART: PDZ/DHR/GLGF domain protein KEGG, DegP/HtrA, do-like protein YP_005744341.1 identified by match to protein family HMM PF06338 YP_005744342.1 contains and IDEAL PFAM doman YP_005744347.1 contains an N-terminal signal sequence YP_005744348.1 PFAM: ABC transporter related SMART: AAA ATPase KEGG: sav:SAV1035 conserved hypothetical protein YP_005744353.1 conatins a iron-dicitrate transporter substrate-binding subunit domain, identified by match to protein family HMM PF01497 YP_005744357.1 systematic name is 1,4-dihydroxy-2-naphthoate octaprenyltransferase YP_005744367.1 Identified by match to protein family HMM PF01047. Domain similarity with Mar proteins (multiple antibiotic resistance, a non-specific resistance system). YP_005744368.1 PFAM: N-acetylmuramoyl-L-alanine amidase, family 2; Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase SMART: Lysozyme subfamily 2 YP_005744372.1 TIGRFAM: cell envelope-related function transcriptional attenuator, LytR/CpsA family PFAM: cell envelope-related transcriptional attenuator KEGG: sas:SAS0991 hypothetical protein YP_005744373.1 identified by match to protein family HMM PF00144 YP_005744379.1 PFAM: tetrahydrofolate dehydrogenase/cyclohydrolase KEGG: sav:SAV1063 FolD bifunctional protein YP_005744398.1 part of PTS system YP_005744401.1 identified by match to protein family HMM PF01654 YP_005744413.1 PFAM: helix-turn-helix domain protein; Cupin 2 conserved barrel domain protein KEGG: sao:SAOUHSC_01045 hypothetical protein YP_005744435.1 PFAM: glycerophosphoryl diester phosphodiesterase YP_005744441.1 PFAM: protein of unknown function DUF177 KEGG: sao:SAOUHSC_01077 hypothetical protein YP_005744454.1 an endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids YP_005744457.1 contains a putative phosphoesterase domain YP_005744458.1 MutS2; MutS-II; involved in blocking homologous and homeologous recombination; has ATPase activity stimulated by recombination intermediates; inhibits DNA strand exchange YP_005744465.1 TIGRFAM: non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family PFAM: Ham1 family protein KEGG: sav:SAV1152 HAM1 protein YP_005744482.1 catalyzes the reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP YP_005744511.1 regulates pyrimidine biosynthesis by binding to the mRNA of the pyr genes, also has been shown to have uracil phosphoribosyltransferase activity YP_005744520.1 PFAM: 3-demethylubiquinone-9 3-methyltransferase YP_005744539.1 PFAM: protein of unknown function DUF322 KEGG: sao:SAOUHSC_01192 hypothetical protein YP_005744543.1 poorly understood protein involved in fatty acid and phospholipid biosynthesis YP_005744564.1 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity YP_005744582.1 PFAM: ribosomal protein L7Ae/L30e/S12e/Gadd45 KEGG: sao:SAOUHSC_01245 hypothetical protein YP_005744590.1 PFAM: cell division protein FtsK/SpoIIIE SMART: AAA ATPase KEGG: sav:SAV1276 sporulation-related protein SpoIIIE homologue YP_005744591.1 PFAM: peptidase M16 domain protein KEGG: sao:SAOUHSC_01255 hypothetical protein YP_005744610.1 PFAM: glycerol-3-phosphate responsive antiterminator KEGG: sao:SAOUHSC_01274 glycerol uptake operon antiterminator regulatory protein, putative YP_005744618.1 contains a Restriction endonuclease domain (PFAM:PF04471.5) also YP_005744645.1 contains two transmembrane domains and possible signal peptide YP_005744658.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the YP_005744659.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are presen YP_005744660.1 guanosine 5'-monophosphate oxidoreductase YP_005744675.1 identified by match to protein family HMM PF02660; match to protein family HMM TIGR00023 YP_005744676.1 TIGRFAM: DNA gyrase, B subunit PFAM: DNA gyrase, subunit B domain protein; ATP-binding region, ATPase domain protein domain protein; TOPRIM domain protein; DNA topoisomerase, type IIA, subunit B, region 2 domain protein SMART: DNA topoisomerase II YP_005744678.1 TIGRFAM: amino acid carrier protein PFAM: sodium:alanine symporter KEGG: sao:SAOUHSC_01354 sodium:alanine symporter family protein, putative YP_005744680.1 PFAM: CAT RNA-binding domain protein; PRD domain protein KEGG: sao:SAOUHSC_01356 transcriptional antiterminator YP_005744683.1 this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress YP_005744694.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate YP_005744696.1 considered essential for expression of methicillin resistance YP_005744697.1 considered essential for expression of methicillin resistance YP_005744705.1 TIGRFAM: oligoendopeptidase F PFAM: peptidase M3A and M3B thimet/oligopeptidase F; Oligopeptidase F KEGG: sao:SAOUHSC_01383 hypothetical protein YP_005744726.1 This family consists of several prokaryotic TelA like proteins. TelA and KlA are associated with tellurite resistance and plasmid fertility inhibition. YP_005744728.1 PFAM: branched-chain amino acid transport system II carrier protein KEGG: sao:SAOUHSC_01411 branched-chain amino acid transport system II carrier protein YP_005744739.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis YP_005744741.1 TIGRFAM: carboxyl-terminal protease PFAM: PDZ/DHR/GLGF domain protein; Peptidoglycan-binding domain 1 protein; peptidase S41 KEGG: sav:SAV1420 probable carboxy-terminal processing proteinase YP_005744745.1 this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress YP_005744746.1 identified by match to protein family HMM PF02645; match to protein family HMM TIGR00762 YP_005744758.1 PFAM: amino acid permease-associated region YP_005744761.1 PFAM: 5'-3' exonuclease SMART: Helix-hairpin-helix domain protein class 2 KEGG: sab:SAB1305c probable 5'-3' exonuclease YP_005744771.1 functions in homologous recombination, DNA repair, and chromosome segregation; binds preferentially to three- and four-stranded DNA intermediates; introduces specific nick sites in four-stranded DNA substrates; functions similarly to Escherichia coli RuvC YP_005744775.1 TIGRFAM: primosome, DnaD subunit PFAM: DnaD and phage-associated region KEGG: sam:MW1343 hypothetical protein, similar to chromosome replication initiation protein dnaD YP_005744786.1 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis YP_005744792.1 Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone YP_005744793.1 pfam07307: component A of hexaprenyl diphosphate synthase YP_005744806.1 KEGG: sao:SAOUHSC_01505 hypothetical protein YP_005744819.1 PFAM: protein of unknown function DUF309 KEGG: sao:SAOUHSC_01590 hypothetical protein YP_005744821.1 identified by similarity to EGAD:14407; match to protein family HMM PF01475 YP_005744822.1 PFAM: NUDIX hydrolase KEGG: sav:SAV1499 ADP-ribose pyrophosphatase YP_005744826.1 identified by match to protein family HMM TIGR02651 YP_005744829.1 PFAM: helix-turn-helix- domain containing protein AraC type; transcription activator effector binding KEGG: sao:SAOUHSC_01600 hypothetical protein YP_005744852.1 PFAM: creatinase; peptidase M24 KEGG: sav:SAV1529 Xaa-Pro dipeptidase YP_005744860.1 PFAM: shikimate kinase KEGG: sab:SAB1410c hypothetical protein YP_005744867.1 PFAM: type II secretion system protein E KEGG: sas:SAS1482 competence protein ComGA YP_005744868.1 PFAM: beta-lactamase domain protein KEGG: sao:SAOUHSC_01644 hypothetical protein YP_005744876.1 identified by match to protein family HMM PF01475, ferric-uptake regulator YP_005744890.1 PFAM: diacylglycerol kinase KEGG: sao:SAOUHSC_01671 diacylglycerol kinase, putative YP_005744895.1 PFAM: protein of unknown function DUF107 KEGG: sab:SAB1446c probable membrane protein YP_005744915.1 involved in late steps of large ribosomal assembly YP_005744917.1 PFAM: GTP-binding protein HSR1-related KEGG: sav:SAV1597 similar to GTPase family protein YP_005744922.1 identified by match to protein family HMM PF01123; match to protein family HMM PF02876 YP_005744926.1 PFAM: PF02786.10 Carbamoyl-phosphate synthase L chain, ATP binding domain YP_005744927.1 PFAM: biotin/lipoyl attachment domain-containing protein KEGG: sas:SAS1543 putative biotin carboxyl carrier protein of acetyl-CoA carboxylase YP_005744934.1 PFAM: O-methyltransferase family 3 KEGG: sav:SAV1614 similar to caffeoyl-CoA O-methyltransferase YP_005744942.1 identified by match to protein family HMM PF00266, PFAM: aminotransferase class V; Pyridoxal-dependent decarboxylase KEGG: sav:SAV1622 iron-sulfur cofactor synthesis protein homolog YP_005744953.1 TIGRFAM: RelA/SpoT family protein PFAM: amino acid-binding ACT domain protein; TGS domain protein; metal-dependent phosphohydrolase, HD sub domain; RelA/SpoT domain protein SMART: metal-dependent phosphohydrolase, HD region YP_005744965.1 PFAM: protein of unknown function DUF464 KEGG: sao:SAOUHSC_01756 hypothetical protein YP_005744972.1 PFAM: Cyclopropane-fatty-acyl-phospholipid synthase; methyltransferase small; Methyltransferase type 11; Methyltransferase type 12 YP_005744973.1 PFAM: ribosomal RNA adenine methylase transferase; putative methyltransferase KEGG: ser:SERP2510 rRNA adenine N-6-methyltransferase YP_005744975.1 KEGG: ser:SERP2508 transposase C YP_005744979.1 PFAM: peptidase A24A prepilin type IV; peptidase A24A domain protein KEGG: sao:SAOUHSC_01764 hypothetical protein YP_005745006.1 TIGRFAM: formamidopyrimidine-DNA glycosylase PFAM: Formamidopyrimidine-DNA glycolase KEGG: sar:SAR1768 formamidopyrimidine-DNA glycosylase YP_005745022.1 identified by match to protein family HMM PF00571; match to protein family HMM PF03061; match to protein family HMM PF07085 YP_005745025.1 PFAM: creatinase; peptidase M24 KEGG: sas:SAS1635 putative metallopeptidase YP_005745027.1 UspA is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. UspA enhances the rate of cell survival during prolonged exposure to such conditions, and may provide a general 'stress endurance' activity. YP_005745028.1 AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA YP_005745033.1 aminotransferase class-V protein YP_005745035.1 acts to negatively regulates ftsZ ring formation by modulating the frequency and position of the ftsZ ring formation YP_005745038.1 PFAM: glycerophosphoryl diester phosphodiesterase YP_005745039.1 related to the OsmC family of osmotically/stress induced proteins YP_005745045.1 PFAM: peptidase S1 and S6 chymotrypsin/Hap SMART: PDZ/DHR/GLGF domain protein KEGG: sao:SAOUHSC_01838 hypothetical protein YP_005745047.1 identified by match to protein family HMM PF04650; match to protein family HMM PF05031; match to protein family HMM TIGR01167; match to protein family HMM TIGR01168 YP_005745053.1 catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate YP_005745066.1 TIGRFAM: tRNA (guanine-N(7)-)-methyltransferase PFAM: putative methyltransferase KEGG: sao:SAOUHSC_01865 hypothetical protein YP_005745067.1 PFAM: aminoglycoside phosphotransferase KEGG: sac:SACOL1799 hypothetical protein YP_005745074.1 TIGRFAM: LPXTG-motif cell wall anchor domain PFAM: YSIRK Gram-positive signal peptide; protein of unknown function DUF1542; sugar-binding domain protein KEGG: sau:SA1577 hypothetical protein YP_005745078.1 contains a radical SAM superfamily domain YP_005745080.1 TIGRFAM: staphylococcal accessory regulator family PFAM: regulatory protein, MarR YP_005745096.1 N-term is truncated by 23aa compared to its orthologs YP_005745102.1 TIGRFAM: RNA polymerase sigma-70 PFAM: sigma-70 region 2 domain protein KEGG: saa:SAUSA300_1722 hypothetical protein YP_005745103.1 Some domain similarity with ComK, Genetic competence transcription factor YP_005745109.1 catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase YP_005745110.1 PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP YP_005745119.1 low complexity sequence YP_005745131.1 predicted esterase of the alpha/beta hydrolase fold YP_005745132.1 catalyzes the formation of protoporphyrin IX from protoporphyrinogen IX YP_005745133.1 protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic YP_005745134.1 catalyzes the formation of coproporphyrinogen from uroporphyrinogen III YP_005745138.1 involved in cell-cycle regulation YP_005745154.1 KEGG: sao:SAOUHSC_01987 hypothetical protein YP_005745156.1 TIGRFAM: putative iron-sulfur cluster binding protein PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; domain of unknown function DUF1730 KEGG: sar:SAR1947 putative iron-sulphur protein YP_005745159.1 PFAM: phosphotransferase system EIIC KEGG: sao:SAOUHSC_01992 phosphotransferase system, EIIC domain protein YP_005745165.1 PFAM: protein of unknown function DUF939 KEGG: sab:SAB1798 probable membrane protein YP_005745169.1 PFAM: membrane-bound metal-dependent hydrolase KEGG: sao:SAOUHSC_02006 hypothetical protein YP_005745205.1 PFAM: transcriptional activator RinB KEGG: sao:SAOUHSC_02053 transcriptional activator RinB-related protein YP_005745210.1 similar to ORF31 of bacteriophage phi ETA [Bacteriophage phiNM1] YP_005745213.1 potential pseudogene, truncated compared to orthologs YP_005745219.1 identified by similarity to EGAD:21924; match to protein family HMM PF03796 YP_005745224.1 DNA single-strand annealing protein YP_005745240.1 PFAM: Radical SAM domain protein; YfkB-like domain protein KEGG: sav:SAV1877 similar to thioredoxin-like oxidoreductase YP_005745244.1 PFAM: low molecular weight phosphotyrosine protein phosphatase, identified by match to protein family HMM PF01451 YP_005745251.1 Identified by match to protein family HMM PF00557; match to protein family HMM TIGR00500. Catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn YP_005745265.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes plac YP_005745267.1 PFAM: CamS sex pheromone cAM373 family protein KEGG: sav:SAV1903 sex pheromone staph-cAM373 precursor YP_005745271.1 this protein binds to tryptophan and represses transcription of the Trp operon YP_005745300.1 PFAM: MAP domain protein, Originally encoded a novel 72-kDa surface protein of S. aureus capable of binding to several extracellular matrix proteins, including fibronectin, fibrinogen, vitronectin, bone sialoprotein, and thrombospondin. May undergo programmed frameshifting. YP_005745301.1 Originally encoded a novel 72-kDa surface protein of S. aureus capable of binding to several extracellular matrix proteins, including fibronectin, fibrinogen, vitronectin, bone sialoprotein, and thrombospondin. May undergo programmed frameshifting. YP_005745316.1 ortholog (SE_p514) in Staphylococcus epidermidis ATCC 12228 YP_005745330.1 PFAM: GCN5-related N-acetyltransferase; aminoglycoside phosphotransferase KEGG: efa:EFA0061 6'-aminoglycoside N-acetyltransferase YP_005745332.1 Part of a ME YP_005745347.1 similarity with Bacterial Ig-like domain YP_005745355.1 PFAM: peptidase S14 ClpP KEGG: saa:SAUSA300_1939 phi77 ORF015-like protein, putative protease YP_005745362.1 PFAM: transcriptional activator RinB KEGG: sao:SAOUHSC_02202 hypothetical protein YP_005745384.1 Some Domain similarity with HTH_XRE (Helix-turn-helix XRE-family like proteins) YP_005745385.1 PFAM: helix-turn-helix domain protein; peptidase S24 S26A and S26B KEGG: sav:SAV1998 repressor homolog YP_005745390.1 PFAM: phage integrase family protein KEGG: sau:SA1810 integrase YP_005745391.1 PFAM: Endonuclease/exonuclease/phosphatase YP_005745395.1 possible polyketide biosynthesis O-methyltransferase YP_005745401.1 GroEL is the larger subunit of the GroEL/GroES cytosolic chaperonin YP_005745402.1 GroES is the smaller subunit of the GroEL/GroES cytosolic chaperonin YP_005745403.1 some identity with putative membrane peptidase ydiL YP_005745407.1 Delta-lysin is a 26 amino acid, hemolytic peptide toxin secreted by Staphylococcus aureus YP_005745412.1 identified by similarity to EGAD:129878; match to protein family HMM PF00294 YP_005745416.1 Some domain similarity with SirA-like protein YP_005745424.1 predicted to have essential role in cell wall biosynthesis YP_005745428.1 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis YP_005745433.1 catalyzes the formation of 2-oxobutanoate from L-threonine; biosynthetic YP_005745435.1 Domain similarity with SprT (predicted to have roles in transcription elongation). Contains a conserved HExxH motif, indicating a metalloprotease function. YP_005745436.1 contains an S1 RNA binding domain at C-terminal YP_005745441.1 PFAM: PemK family protein YP_005745456.1 identified by match to protein family HMM PF01098, similar to rod shape determining protein RodA FtsW YP_005745464.1 catalyzes the formation of 4-methyl-5-(2-phosphoethyl)-thiazole and ADP from 4-methyl-5-(2-hydroxyethyl)-thiazole and ATP YP_005745469.1 TIGRFAM: single-strand binding protein PFAM: single-strand binding protein/Primosomal replication protein n KEGG: sao:SAOUHSC_02334 bacteriophage L54a, single-stranded DNA binding protein YP_005745474.1 TIGRFAM: ATP synthase F1, epsilon subunit PFAM: H+transporting two-sector ATPase delta/epsilon subunit KEGG: sao:SAOUHSC_02340 ATP synthase F1, epsilon subunit YP_005745475.1 produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit YP_005745476.1 produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit YP_005745477.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit YP_005745478.1 TIGRFAM: ATP synthase F1, delta subunit PFAM: H+transporting two-sector ATPase delta (OSCP) subunit KEGG: sas:SAS2009 putative ATP synthase delta chain YP_005745479.1 TIGRFAM: ATP synthase F0, B subunit PFAM: H+transporting two-sector ATPase B/B' subunit KEGG: sao:SAOUHSC_02347 ATP synthase F0, B subunit YP_005745480.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0 YP_005745481.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0 YP_005745489.1 TIGRFAM: modification methylase, HemK family PFAM: methyltransferase small KEGG: sav:SAV2117 hemK protein YP_005745495.1 contains HxlR-like helix-turn-helix N-terminal domain YP_005745500.1 participates in both the initiation and recycling phases of transcription; in the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis b YP_005745501.1 PFAM: GCN5-related N-acetyltransferase KEGG: sav:SAV2129 similar to spermine/spermidine acetyltransferase blt YP_005745502.1 catalyzes the formation of (R)-4'-phosphopantothenate from (R)-pantothenate in coenzyme A biosynthesis; type II pantothenate kinases are not regulated by feedback inhibition by coenzyme A YP_005745514.1 TIGRFAM: mannose-6-phosphate isomerase, class I PFAM: mannose-6-phosphate isomerase type I KEGG: saa:SAUSA300_2096 mannose-6-phosphate isomerase YP_005745523.1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6Pusing glutamine as a nitrogen source YP_005745524.1 TIGRFAM: PTS system, mannitol-specific IIC subunit PFAM: phosphotransferase system EIIC; phosphotransferase system lactose/cellobiose-specific IIB subunit KEGG: sao:SAOUHSC_02400 PTS system, mannitol-specific component, putative YP_005745526.1 PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2 KEGG: sao:SAOUHSC_02402 PTS system, mannitol-specific IIa component, putative YP_005745540.1 contains a nucleoside recognition domain YP_005745543.1 PFAM: periplasmic binding protein KEGG: sao:SAOUHSC_02430 ABC transporter periplasmic binding protein, putative YP_005745545.1 PFAM: IucA/IucC family protein KEGG: sao:SAOUHSC_02434 hypothetical protein YP_005745568.1 PFAM: aldo/keto reductase KEGG: sao:SAOUHSC_02460 hypothetical protein YP_005745571.1 PFAM: polysaccharide lyase family 8; polysaccharide lyase family 8 domain protein; polysaccharide lyase 8 alpha-helical KEGG: sav:SAV2202 hyaluronate lyase precursor YP_005745573.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IIB PFAM: sucrose-6F-phosphate phosphohydrolase; Haloacid dehalogenase domain protein hydrolase type 3 KEGG: sav:SAV2204 hypothetical protein YP_005745580.1 possible gene remnant, similar to C-term helicase. YP_005745585.1 PFAM: ABC transporter related SMART: AAA ATPase KEGG: ABC transporter, ATP-binding protein, putative YP_005745594.1 identified by match to protein family HMM PF00344; match to protein family HMM TIGR00967 YP_005745626.1 this protein is considered a factor influencing the level of methicillin resistance YP_005745629.1 identified by match to protein family HMM PF01047 YP_005745635.1 PFAM: molybdopterin biosynthesis MoaE protein KEGG: sav:SAV2271 molybdopterin converting factor YP_005745644.1 involved in the production or activity of formate dehydrogenase-H which is active when nitrate is not present during anaerobic growth YP_005745650.1 involved in urea transport, promoting its entry into the cell , which can can be advantageous for bacteria as its hydrolysis by urease generates ammonium which is an efficient source of nitrogen and, through its buffering capacity, can also provide resistance to acidic conditions YP_005745658.1 TIGRFAM: staphylococcal accessory regulator family KEGG: sao:SAOUHSC_02566 hypothetical protein YP_005745662.1 identified by match to protein family HMM PF05257 YP_005745675.1 weak CAAX amino terminal protease family domain YP_005745692.1 TIGRFAM: amidohydrolase PFAM: peptidase M20; peptidase dimerisation domain protein KEGG: sav:SAV2329 similar to amino acid amidohydrolase YP_005745695.1 PFAM: regulatory protein LysR; LysR substrate-binding KEGG: sao:SAOUHSC_02608 hypothetical protein YP_005745698.1 identified by match to protein family HMM PF02517, membrane associated protease YP_005745699.1 TIGRFAM: ribose 5-phosphate isomerase PFAM: Ribose 5-phosphate isomerase KEGG: sao:SAOUHSC_02612 ribose 5-phosphate isomerase, putative YP_005745700.1 contains a MOSC domain identified in the molybdenum cofactor sulfurase YP_005745720.1 identified by match to protein family HMM PF02698 YP_005745722.1 PFAM: ABC transporter related SMART: AAA ATPase, sometimes referred to as hemin import ATP-binding protein hrtA YP_005745723.1 PFAM: protein of unknown function DUF214 KEGG: sao:SAOUHSC_02641 permease, putative domain protein YP_005745729.1 TIGRFAM: L-lactate transport PFAM: L-lactate permease KEGG: sab:SAB0049 L-lactate permease YP_005745732.1 PFAM: GCN5-related N-acetyltransferase KEGG: sao:SAOUHSC_02651 hypothetical protein, similar to transcription repressor of sporulation, septation and degradation paiA YP_005745734.1 PFAM: GCN5-related N-acetyltransferase KEGG: sav:SAV2371 similar to attachment to host cells and virulence YP_005745744.1 has been referred to as general stress protein 26 YP_005745752.1 PFAM: regulatory protein MerR; TipAS antibiotic-recognition domain protein KEGG: sao:SAOUHSC_02674 hypothetical protein YP_005745771.1 contains a weak DSBA-like thioredoxin domain YP_005745781.1 TIGRFAM: beta-channel forming cytolysin PFAM: Combined Leucocidin/ASH4 hemolysin KEGG: sao:SAOUHSC_02708 gamma-hemolysin h-gamma-II subunit, putative YP_005745782.1 TIGRFAM: beta-channel forming cytolysin PFAM: Combined Leucocidin/ASH4 hemolysin KEGG: sam:MW2343 gamma-hemolysin component C YP_005745783.1 TIGRFAM: beta-channel forming cytolysin PFAM: Combined Leucocidin/ASH4 hemolysin KEGG: sao:SAOUHSC_02710 leukocidin F subunit precursor YP_005745792.1 PFAM: glycerate kinase KEGG: sao:SAOUHSC_02723 glycerate kinase, putative YP_005745797.1 Domain similarity with Icc (phosphohydrolases), SbcD (DNA repair exonuclease) and, Calcineurin-like phosphoesterase YP_005745801.1 drug resistance-involved membrane protein YP_005745804.1 ketopantoate reductase; catalyzes the NADPH reduction of ketopantoate to pantoate; functions in pantothenate (vitamin B5) biosynthesis YP_005745810.1 PFAM: Domain of unknown function DUF1801 YP_005745812.1 PFAM: Carboxylesterase type B KEGG: sav:SAV2451 similar to para-nitrobenzyl esterase chain A YP_005745819.1 PFAM: protein of unknown function DUF1307 YP_005745832.1 PFAM: C4-dicarboxylate anaerobic carrier; AbgT putative transporter KEGG: sav:SAV2473 similar to aminobenzoyl-glutamate transport protein YP_005745837.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR domain protein KEGG: sav:SAV2478 similar to oxidoreductase YP_005745842.1 PFAM: helicase domain protein; type III restriction protein res subunit; DEAD/DEAH box helicase domain protein SMART: DEAD-like helicases KEGG: sas:SAS2376 putative helicase YP_005745844.1 may be bifunctional as phosphoglucomutase YP_005745848.1 TIGRFAM: staphylococcal accessory regulator family KEGG: sas:SAS2384 putative staphylococcal accessory regulator YP_005745849.1 TIGRFAM: staphylococcal accessory regulator family PFAM: regulatory protein, MarR. This gene has multiple paralogs including a regular form and a tandem-repeat version YP_005745851.1 TIGRFAM: LPXTG-motif cell wall anchor domain PFAM: surface protein from Gram-positive cocci anchor region; Fibronectin binding repeat; YSIRK Gram-positive signal peptide KEGG: sav:SAV2502 fibronectin-binding protein homolog YP_005745853.1 TIGRFAM: LPXTG-motif cell wall anchor domain PFAM: surface protein from Gram-positive cocci anchor region; Fibronectin binding repeat; YSIRK Gram-positive signal peptide KEGG: sav:SAV2502 fibronectin-binding protein homolog YP_005745859.1 PFAM: RelA/SpoT domain protein KEGG: sao:SAOUHSC_02811 hypothetical protein YP_005745875.1 catalyzes the formation of pyruvate from lactate YP_005745883.1 some similarity to phosphotransferase system, fructose-specific IIC component YP_005745890.1 identified by match to protein family HMM PF04172. The two products of the lrgAB operon are potential membrane proteins, and LrgA and LrgB are both thought to control of murein hydrolase activity and penicillin tolerance YP_005745891.1 PFAM: LrgA family protein. The two products of the lrgAB operon are potential membrane proteins, and LrgA and LrgB are both thought to control of murein hydrolase activity and penicillin tolerance. YP_005745892.1 PFAM: regulatory protein LysR; LysR substrate-binding KEGG: saa:SAUSA300_2480 transcriptional regulator, LysR family YP_005745893.1 PFAM: CHAP domain containing protein KEGG: sao:SAOUHSC_02855 LysM domain protein YP_005745898.1 PFAM: UvrB/UvrC protein; AAA ATPase central domain protein; ATPase AAA-2 domain protein SMART: AAA ATPase KEGG: sav:SAV2548 ATP-dependent Clp proteinase chain YP_005745900.1 TIGRFAM: ferrous iron transport protein B; small GTP-binding protein PFAM: GTP-binding protein, HSR1-related; Ferrous iron transport protein B domain protein; Ferrous iron transport B domain protein; nucleoside recognition domain protein YP_005745905.1 catalyzes the conversion of 1-proline-5-carboxylate dehydrogenase to L-glutamate YP_005745918.1 PFAM: acyltransferase 3 KEGG: sas:SAS0844 hypothetical protein YP_005745920.1 similar to regulatory protein (pfoS/R) YP_005745932.1 PFAM: cobalamin synthesis protein P47K; cobalamin synthesis CobW domain protein KEGG: sav:SAV2582 similar to cobalamin synthesis related protein CobW YP_005745938.1 PFAM: Penicillinase repressor KEGG: sau:SAP012 penicillinase repressor YP_005745940.1 PFAM: beta-lactamase KEGG: sau:SAP010 beta-lactamase YP_005745960.1 PFAM: protein of unknown function DUF208 YP_005745968.1 PFAM: alpha-acetolactate decarboxylase KEGG: sao:SAOUHSC_02921 alpha-acetolactate decarboxylase YP_005745971.1 catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate YP_005745976.1 possibly involved in biosynthesis of extracellular polysaccharides YP_005745986.1 catlayzes the formation of siroheme from precorrin-2 YP_005745991.1 PFAM: ABC transporter related SMART: AAA ATPase YP_005745996.1 contains a MarR-family domain YP_005745998.1 fibrinogen and keratin-10 binding surface anchored protein YP_005746008.1 PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; PRD domain protein; Helix-turn-helix type 11 domain protein; Helix-turn-helix Mga DNA-binding trans-acting positive regulator KEGG: sav:SAV2640 similar to transcription antiterminator BglG family YP_005746016.1 TIGRFAM: Conserved hypothetical protein CHP02918 PFAM: glycosyl transferase group 1; Protein of unknown function DUF1975 KEGG: sav:SAV2648 similar to lipopolysaccharide biosynthesis protein YP_005746027.1 this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; a fusion protein of this enzyme with MsrB provides protection against oxidative stress in Neisseria gonorrhoeae YP_005746030.1 CobQ/CobB/MinD/ParA nucleotide binding domain YP_005746033.1 predicted polysaccharide polymerase involved in biofilm formation; required for the synthesis of the beta-1,6-N-acetylglucosamine polysaccharide YP_005746035.1 involved in polysaccharide intercellular adhesin (PIA) synthesis/biofilm formation-like protein YP_005746043.1 PFAM: aminotransferase class I and II KEGG: sav:SAV2677 histidinol-phosphate aminotransferase YP_005746046.1 may allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine YP_005746050.1 PFAM: ABC transporter related SMART: AAA ATPase KEGG: sac:SACOL2708 ABC transporter, ATP-binding protein YP_005746051.1 PFAM: protein of unknown function DUF1393 KEGG: sav:SAV2685 similar to integral membrane protein, Annotated as Substrate-specific component MtsA of methionine-regulated ECF transporter in Saa_2981 YP_005746063.1 PFAM: N-acetyltransferase KEGG: sav:SAV2699 similar to N-hydroxyarylamine O-acetyltransferase YP_005746067.1 follows the vraDE vancomycin resistance locus